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- Antibody Data
- Antigen structure
- References [270]
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- Product number
- 28674-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- Claudin 1 antibody
- Antibody type
- Polyclonal
- Description
- Claudin 1 antibody (Cat. #28674-1-AP) is a rabbit polyclonal antibody that shows reactivity with Human, Mouse, Rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Periplaneta americana extract ameliorates recurrent oral ulcers in rats by enhancing the intestinal epithelial barrier and regulating gut microbiota.
Integrating bioinformatic prediction and the "gut microbiota-inflammation-skin axis" to decipher the mechanisms of quercetin (from Evodia rutaecarpa) in diabetic wound healing.
Lactobacillus rhamnosus confers protection against enteropathogenic bacteria by enhancing mucosal immunity and epithelial barrier function.
Identification of Key Genes Associated With Epithelial Barrier Dysfunction by Comprehensive Analysis and Experimental Validation.
Puerarin Improves Glucose and Lipid Metabolism in Type 2 Diabetes by Regulating Gut Microbiota Homeostasis and Promoting Adipose Tissue Thermogenesis.
Yeast β-glucan alleviates alcohol-related brain injury by restoring gut-brain axis homeostasis.
Glucuronolactone Promotes Mucin Sulfation to Alleviate Deoxynivalenol-Induced Intestinal Injury via Microbiota-Dependent and -Independent AHR Activation.
Effect of Dietary Electrolyte Balance in Low-Protein Diet on Intestinal Barrier, Mitochondrial Function and Carcass Quality of Growing Pigs.
Therapeutic potential of Isatidis Radix alkaloids in RSV pneumonia: A focus on AhR-mediated pulmonary barrier repair.
Fermented grape pomace alleviates Salmonella typhimurium-induced Hepatointestinal inflammation: FXR mediates protection by orchestrating bile acid homeostasis and suppressing the colonic NLRP3 Inflammasome.
Scutellaria baicalensis extract prevents metabolic dysfunction-associated steatotic liver disease by modulating the gut-liver axis in high-fat diet mice.
Engineered Bacillus subtilis WB600/ZD reduces post-weaning diarrhea in piglets by modulating gut microbiota and aryl hydrocarbon receptor (AHR) signaling.
RAB3B regulates vesicle uptake and tight junction integrity in amniotic epithelial cells and is downregulated in premature rupture of membranes.
Ketogenic diet alleviates septic lung injury via microbial gut-lung axis.
Research based on serine metabolism indicates mesenchymal stem cells alleviate psoriasis by regulating the PSPH-PINK1-Parkin-NLRP3 pathway in HaCaT.
Maternal β-hydroxybutyrate during the dry period is associated with altered epithelial cell regulation and rumen morphology of offspring as calves.
Shenqi funeng xingnao prescription regulated the TNF/NOD‒like receptor signaling pathway and brain-gut axis dysfunction caused by exercise-induced fatigue.
High fluoride exposure disrupts gut microbiota and induces intestinal barrier damage via RhoA/ROCK-mediated cytoskeletal remodeling.
Rutin targets PD-L1 for the treatment of atopic dermatitis: network pharmacological analysis and experimental evidence.
Unraveling the active ingredients and molecular mechanisms of Qinghua Changyan granule against irritable bowel syndrome with diarrhea: Effects on gut microbiota and glutamine transport via an integrative approach combining UHPLC-MS/MS and experimental verification.
Limosilactobacillus reuteri DSM17938 Attenuates Neuroinflammatory Responses After Spinal Cord Injury by Modulating Tryptophan Metabolism.
Chrysophanein of Rhubarb rescues ILC3-Derived IL-22 by blocking CCDC25/ILK/HIF-1α for mucosal healing in ulcerative colitis mice.
Ameloblastin Amphipathic Helix Motif mediates Ameloblast Polarization and Prismatic Enamel Formation via a RhoA Signaling Pathway.
Strategically isolated bacteriophages targeting ETEC K88 (F4) alleviate post-weaning diarrhea in piglets via modulation of gut microbiota and inflammatory responses.
Time-dependent Lactiplantibacillus plantarum (LP) AS21 intervention enhances mesalazine efficacy by modulating gut microbiota and host immunometabolic responses in DSS-induced colitis.
Effects of Modified Xuanbai Chengqi Decoction against secondary Streptococcus pneumoniae infection following influenza virus infection: A multi-omics analysis.
Combined metabolomics and gut microbiota analysis reveals the protective effects of α-monoglucosyl rutin against cyclophosphamide-induced intestinal injury.
Gegen Qinlian decoction ameliorates experimental colitis in miceferroptosis pathway.
Cutibacterium acnes-macrophage fusion membrane coating Cu/Zn-MOF for psoriasis treatment via pathological innate lymphoid cells inhibition.
Genome-wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer.
DLGAP5 regulates malignancy and lenvatinib sensitivity of hepatocellular carcinoma through AKT/mTOR/NF-κB pathway.
Anti-Inflammatory Effects of Marine-Derived Resorcylic Acid Lactone Derivatives in Ulcerative Colitis via the MAPK/ERK Pathway.
A novel role of Dermatophagoides farinae-derived miR-276-3p in aggravating mite-induced allergic airway inflammation.
Butyrate ameliorates doxorubicin-induced heart failure by inhibiting cardiomyocyte ferroptosis through the gut-heart axis.
Integrating serum pharmacochemistry, network pharmacology, gut microbiota and transcriptomic strategies to reveal the active ingredients and mechanism of Changma Xifeng tablet in the treatment of tourette syndrome.
Atractylenolide III Alleviates the Lipid Metabolic Disorders in Ovariectomy-Induced Estrogen-Deficient Mice Through Repairing Intestinal Inflammation and Microenvironment.
Brucea javanica oil emulsion ameliorates ulcerative colitis by upregulating Deoxyribonuclease 2 to suppress cytosolic DNA-sensing signaling.
Diabetes Mellitus Facilitates Gallstone Formation Through CXCR2-NETs-Mediated Liver-Bile Barrier Damage.
Neuroprotective Effects of Time-Restricted Feeding Combined With Different Protein Sources in MPTP-Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism.
Oral Exposure to Polypropylene Microplastics Exacerbates Cow's Milk Allergy in a Murine Model by Skewing the DCs/T-Cell Response toward Th2 Polarization.
Fucoidan alleviates chemotherapy-induced steatohepatitis by regulating the gut-liver axis.
Palladium nanozyme loaded metal-organic framework eyedrops alleviate oxidative stress for dry eye treatment.
HMGB1 Exacerbates Intestinal Barrier Damage by Inducing Ferroptosis Through the TLR4/NF-κB/GPX4 Pathway in Ulcerative Colitis.
Curcumin modulated gut microbiota and alleviated renal fibrosis in 5/6 nephrectomy-induced chronic kidney disease rats.
SIGIRR Alleviates Intestinal Mucosal Damage in Severe Acute Pancreatitis via the TLR4 Signaling Pathway.
Ginsenoside Reshapes Intestinal Microecology to Alleviate Microgravity Stress.
Network pharmacology-guided investigation of Fuzheng Yanggan Huaxian decoction in a CCL(4)-induced hepatic fibrosis mouse model: involvement of the TLR4-MAPK/NF-κB signaling axis and intestinal barrier.
Deciphering immune cell interaction aberrations in necrotizing enterocolitis: the regulatory role of DHRS7.
Berberine-taxifolin co-administration attenuates inflammatory response and intestinal barrier injury via nf-κB/NLRP3 suppression in colitis.
Modulation of gut microbiota by Gardeniae Fructus oil exerts TLR4/NF-κB/NLRP3 pathway-mediated antidepressant effects based on transcriptomics and fecal transplantation.
Unveiling the neutrophil-Notch2-ISC axis: asiatic acid's therapeutic strategy in infectious colitis.
Lactobacillus rhamnosus GG attenuates MASLD/MASH progression by modulating gut microbiota and metabolic pathways.
Vespa orientalis pupae peptide hydrolysates modulate NF-κB signaling in LTA-induced pneumonia from clinical Enterococcus faecalis isolates: implications for gut microbiota.
Effect of four traditional Chinese medicine monomers on mechanical barrier damage and inflammation response of IPEC-J2 cells caused by soybean 7S globulin.
Wendan Decoction exerts therapeutic effects on insomnia by regulating gut microbiota and tryptophan metabolism.
Zinc Alleviates Gut Barrier Dysfunction by Promoting the Methylation of AKT.
Cardamonin alleviates intestinal inflammation in LPS-induced weaned piglets through the AhR/Nrf2/NLRP3 signaling pathway.
The deubiquitinase USP2 preserves intestinal barrier through the TRAF6/NF-κB/MLCK/MLC signaling in ulcerative colitis.
Sweroside ameliorates intestinal mucosal microcirculatory disturbances in ulcerative colitis mice by modulating the VEGF and Hippo signaling pathways.
Lactobacillus plantarum CCFM639 ameliorates vascular dysfunction in mice with Kawasaki disease involving eNOS/NO pathway.
Butyrate enhances recovery of chemotherapy-induced oral mucositis by enhancing tight junction protein expression and inhibiting inflammatory responses.
Dendrobium officinale polysaccharide relieves hepatointestinal damage induced by chronic arsenic exposure in chickens by regulating gut microbiota.
TSP50 in Neural Stem Cells Regulates Aging-Related Cognitive Decline and Neuroinflammation by Altering the Gut Microbiota.
Genetical TRPV4 deletion-associated gut microbiota alleviates cardiac dysfunction in mice with diabetic cardiomyopathy.
Intestinal Epithelial-Derived USP13 Alleviates Colonic Inflammation by Suppressing GRP78-mediated Endoplasmic Reticulum Stress.
Nuclear receptor Nr1d1 links sleep deprivation to intestinal homeostasis via microbiota-derived taurine.
Psoralen alleviates ulcerative colitis by suppressing inflammation, modulating oxidative stress, and regulating ferroptosis.
Echinacoside: A potential therapeutic approach for alcohol-related liver disease by alleviating intestinal microbial dysbiosis, intestinal barrier dysfunction, and liver inflammation mediated by the endotoxin-TLR4/NF-κB pathway.
Oral absorption mechanisms of Astragalus polysaccharides and potential as an excipient to increase the absorption of flavonoids.
The effect of anthocyanin extract from Lycium ruthenicum Murray on intestinal barrier function in Bamei ternary pigs.
Co-administration of berberine and evodiamine: Mitigating evodiamine-induced hepatotoxicity and potentiating colitis treatment.
Bavachinin alleviates allergic rhinitis by modulating gut microbiota and inhibiting NLRP3-mediated epithelial pyroptosis through PI3K/AKT/NF-κB signaling pathway.
Autism-Associated Gut Microbiota-Derived Enterococcus facium Modulates Gut-Brain Axis Function and Behavior in Mice.
Engineering Escherichia coli nissle 1917 with lactonase ZHD101 alleviates zearalenone-induced intestinal disruption and reproductive toxicity in rat.
HIF-1α Enhances Intestinal Injury and Inflammation in Severe Acute Pancreatitis Through NLRP3 Inflammasome Activation.
Gut commensal Lachnospiraceae bacteria contribute to anti-colitis effects of Lactiplantibacillus plantarum exopolysaccharides.
Puerarin improves MASLD by remodeling intestinal microenvironment to promote mitochondrial fusion and autophagy.
Extracellular Vesicles From Lactobacillus fermentum Enhance Intestinal Barrier Integrity and Restore Gut Microbial Homeostasis in Experimental Murine Colitis.
Drinking Water Temperature Impacts the Pathogenesis of DSS-Induced Ulcerative Colitis by Regulating Intestinal Barrier Function and Remodeling the Gut Microbiota Composition.
Uncovering the molecular mechanisms of tonifying kidney and activating blood Decoction against myocardial fibrosis using network Pharmacology and experimental validation.
Atractylenolide-1 Alleviates Ulcerative Colitis via Restraining RhoA/ROCK/MLC Pathway-Mediated Intestinal Barrier Dysfunction.
Enhanced alleviation of the selenite-grafted soluble and nondigestive Chinese Yam polysaccharides on nonylphenol-induced cytotoxicity and barrier damage in intestinal epithelial cells.
Garlic-Derived Exosome-Like Nanoparticles Enhance Gut Homeostasis in Stressed Piglets: Involvement of Lactobacillus reuteri Modulation and Indole-3-propionic Acid Induction.
Fisetin alleviates Salmonella typhimurium-induced colitis through the TLR2/TLR4-NF-κB pathway, regulating microbiota, and repressing intracellular bacterial proliferation by focal adhesion kinase.
Supplementary Hesperidin Alleviated CPT-11-Induced Diarrhea by Modulating Gut Microbiota and Inhibiting the IL-17 Signaling Pathway.
Why do microplastics aggravate cholestatic liver disease? The NLRP3-mediated intestinal barrier integrity damage matter.
Ginsenoside Rh4 inhibits colorectal cancer via the modulation of gut microbiota-mediated bile acid metabolism.
Interaction of osteopontin with α-lactalbumin and their synergistic effects in protecting intestinal barrier injury.
Oleic acid regulates CD4+ T cells differentiation by targeting ODC1-mediated STAT5A phosphorylation in Vogt-Koyanagi-Harada disease.
Probiotic Combination of Limosilactobacillus fermentum HF07 and Lactococcus lactis HF08 Targeting Gut Microbiota-Secondary Bile Acid Metabolism Ameliorates Inflammation and Intestinal Barrier Dysfunction in Aging Colitis.
Enhancing intestinal epithelial microtubule stability could alleviate IBD symptoms.
TSP50 deficiency in neural stem cells aggravates colitis in mice by altering intestinal microbiome.
Flos lonicerae polysaccharide alleviates inflammatory bowel disease by improving intestinal microbiota and inhibiting oxidative stress and the NF-κB pathway.
Betulinic Acid Reduces Intestinal Inflammation and Enhances Intestinal Tight Junctions by Modulating the PPAR-γ/NF-κB Signaling Pathway in Intestinal Cells and Organoids.
HucMSC-Ex alleviates inflammatory bowel disease by regulating O-GlcNAcylation modification of RACK1 in intestinal epithelial cells.
The critical role of Id2 gene in mesenchymal stem cell therapy for colitis through regulating immune response and microbiota.
An engineered antimicrobial peptide Z-FV7 demonstrates bactericidal efficacy against multidrug-resistant Escherichia coli in a murine model of endometritis.
Gentiopicroside improves DSS-induced ulcerative colitis and secondary liver injury in mice by enhancing the intestinal barrier and regulating the gut microbiome.
Protective effect of a novel nonsteroidal organoselenium compound SLL-1-43 on ulcerative colitis through down-regulating NOX2 signaling pathway in vitro and in vivo.
Terrestrosin D promotes autophagy and apoptosis of breast cancer cells through PSMD1-dependent activation of P53 pathway.
Changdiqing decoction (CDQD) ameliorates colitis via suppressing inflammatory macrophage activation and modulating gut microbiota.
Exploring the Mechanism of Kidney Injury in Mice Induced by High-Fat Diet and Polystyrene Nanoplastics Co-Exposure Through the Kidney-Gut Axis.
Tryptophan-Rich Diet Improves High-Fat Diet-Induced Cognitive Dysfunction and Blood-Brain Barrier Disruption in C57BL/6 Mice through FFAR3 Activation.
Biological and metabolomic insights into RACGAP1-mediated growth and progression of clear cell renal cell carcinoma.
Maternal lead exposure impairs offspring growth and intestinal microbiota via AMPK/ULK1 pathway activation.
Luteolin Alleviates Ulcerative Colitis in Mice by Modulating Gut Microbiota and Plasma Metabolism.
The effects of rosmarinic acid and antibiotics on the intestinal morphology, function, and cecal microbiota of broiler chickens.
Cimicifuga heracleifolia kom. Attenuates ulcerative colitis through the PI3K/AKT/NF-κB signaling pathway.
A comparative study on in vitro models of necrotizing enterocolitis induced by single and combined stimulation.
Engineered Bacillus subtilis WB600/ZD prevents Salmonella Infantis-induced intestinal inflammation and alters the colon microbiota in a mouse model.
Notch/IL33/ST2 signaling was involved in the maintenance of intestinal epithelial barrier through regulating tight junction after LPS stimulation.
Brown Algae Polysaccharides Alleviate Diquat-Induced Oxidative Stress in Piglets and IPEC-J2 Cells via Nrf2/ARE Signaling Pathway.
Dihydromyricetin/montmorillonite intercalation compounds ameliorates DSS-induced colitis: Role of intestinal epithelial barrier, NLRP3 inflammasome pathway and gut microbiota.
Berberine Prevents NSAID-Induced Small Intestinal Injury by Protecting Intestinal Barrier and Inhibiting Inflammasome-Associated Activation.
EUK nanozyme-loaded PL&GA coacervate droplets attenuate ulcerative colitis through restoring gut homeostasis and restricting intestinal cell ferroptosis.
Probiotic-based self-crosslinking bio-coating for the treatment of colitis by increasing probiotic colonization.
Co-fermentation of honeysuckle-Cassia seeds by Lactobacillus acidophilus and Bacillus subtilis: A new approach to attenuate alcohol-induced acute gastric mucosal damage and modulate immune response.
Physical prehabilitation improves colonic anastomosis healing in a malnourished rat model only if attached to effective nutritional prehabilitation - Experimental study.
Formononetin and daidzein from Huoxiangzhengqi formula ameliorate Salmonella Typhimurium-induced intestinal flora dysbiosis and barrier dysfunction.
Secondary Bile Acids Modified by Odoribacter Splanchnicus Alleviate Colitis by Suppressing Neutrophil Extracellular Trap Formation.
Qula-derived Limosilactobacillus fermentum TD-3 and Lactococcus lactis MQ1-1 alleviate aging-related intestinal barrier dysfunction via microbiota-short-chain fatty acid-AMPK/MLCK-tight junction axis.
Nanozymes modulate probiotic tryptophan metabolism to prevent Salmonella infection in mammalian models.
Pharmacokinetic and Pharmacodynamic Evaluation of PZ-2891, an Anti-Alzheimer's Disease Agonist of PANK2.
Nicotine exacerbates MASH via inducing intestinal dysbiosis and barrier dysfunction.
The Effect of 2'-Fucosyllactose on Gut Health in Aged Mice.
Quercetin alleviates ulcerative colitis via regulating gut microbiota and tryptophan metabolism.
Nano-functionalized probiotic treats atherosclerosis via inhibiting intestinal microbiota-TMA-TMAO axis.
The Hormonal Effect of Fibroblast Growth Factor 19 on the Intestinal Adaptation in Pediatric Short Bowel Syndrome: An in Vitro Study Using Patients-Derived Enteroids.
Chronic Arsenic Exposure Causes Alzheimer's Disease Characteristic Effects and the Intervention of Fecal Microbiota Transplantation in Rats.
Apigenin mitigates intestinal barrier dysfunction in sepsis by modulating the AKT signaling pathway.
β-Nicotinamide mononucleotide alleviates Alcohol-Induced liver injury in a mouse model through activation of NAD(+)/SIRT1 signaling pathways.
Flavonoid Extract of Senecio scandens Buch.-Ham. Ameliorates CTX-Induced Immunosuppression and Intestinal Damage via Activating the MyD88-Mediated Nuclear Factor-κB Signaling Pathway.
Modulation of Intestinal Barrier Function and Wnt/β- Catenin Pathway by Sanzi Formula in Colorectal Adenoma Development.
Covalent Grafting of Inorganic Selenium to the Water-Soluble and Nondigestive Chinese Yam Polysaccharides Causes Greater Protection of IEC-6 Cells with Acrylamide Injury.
Card9 deficiency exacerbates vulvovaginal candidiasis by impairing the IL-17 production and vaginal epithelial barrier.
Green Tea Ameliorates Depression-Like Behavior and Cognitive Impairment Induced by High-Fat Diet and Chronic Mild Stress.
Statin therapy associated Lactobacillus intestinalis attenuates pancreatic fibrosis through remodeling intestinal homeostasis.
Overexpression of Plakophilin2 Mitigates Capillary Leak Syndrome in Severe Acute Pancreatitis by Activating the p38/MAPK Signaling Pathway.
Effects of hydroxychloroquine on the mucosal barrier and gut microbiota during healing of mice colitis.
HucMSC-Ex alleviates DSS-induced colitis in mice by decreasing mast cell activation via the IL-33/ST2 axis.
Human umbilical cord mesenchymal stem cells derived-exosomes alleviate LPS-induced cervical inflammation and epithelial-mesenchymal transition.
Bacteroides fragilis capsular polysaccharide A ameliorates ulcerative colitis in rat by recovering intestinal barrier integrity and restoring gut microbiota.
Circadian rhythm disruption-mediated downregulation of Bmal1 exacerbates DSS-induced colitis by impairing intestinal barrier.
Hinesol attenuates DSS-induced ulcerative colitis through the suppression of Src-mediated NF-κB and chemokine signaling pathway.
Carbon monoxide-releasing molecule-3 exerts neuroprotection effects after cardiac arrest in mice: A randomized controlled study.
Dihydroartemisinin Modulates Enteric Glial Cell Heterogeneity to Alleviate Colitis.
miR-155 induces sepsis-associated damage to the intestinal mucosal barrier via sirtuin 1/nuclear factor-κB-mediated intestinal pyroptosis.
Exploring the efficacy and mechanism of Bailing capsule to improve polycystic ovary syndrome in mice based on intestinal-derived LPS-TLR4 pathway.
Integrating metagenomics with metabolomics for gut microbiota and metabolites profiling in acute pancreatitis.
Anemarrhena asphodeloides Bunge polysaccharides alleviate lipoteichoic acid-induced lung inflammation and modulate gut microbiota in mice.
DHA-enriched phosphatidylserine ameliorates cyclophosphamide-induced liver injury via regulating the gut-liver axis.
Involvement of gut microbiota recovery and autophagy induction in Youhua Kuijie formula's protection against experimental ulcerative colitis.
Goat Milk Exosomes Ameliorate Ulcerative Colitis in Mice through Modulation of the Intestinal Barrier, Gut Microbiota, and Metabolites.
Ferulic Acid Inhibits Arsenic-Induced Colon Injury by Improving Intestinal Barrier Function.
Goat milk derived small extracellular vesicles ameliorate LPS-induced intestinal epithelial barrier dysfunction, oxidative stress, and apoptosis by inhibiting the MAPK signaling pathway.
Ginsenoside Rg1 Alleviates Blood-Milk Barrier Disruption in Subclinical Bovine Mastitis by Regulating Oxidative Stress-Induced Excessive Autophagy.
Multiomics profiling uncovers curdione-induced reproductive toxicity in HTR-8/SVneo cells.
TIPE2 aggravates experimental colitis and disrupts intestinal epithelial barrier integrity by activating JAK2/STAT3/SOCS3 signal pathway.
Dapagliflozin ameliorates hepatic steatosis via suppressing LXRα-mediated synthesis of lipids and bile acids.
Inhibition of piezo1 prevents chronic cerebral hypoperfusion-induced cognitive impairment and blood brain barrier disruption.
Integrating Epigenetics, Proteomics, and Metabolomics to Reveal the Involvement of Wnt/β-Catenin Signaling Pathway in Oridonin-Induced Reproductive Toxicity.
Lycium barbarum polysaccharide remodels colon inflammatory microenvironment and improves gut health.
Chaihu Guizhi Ganjiang Decoction attenuates nonalcoholic steatohepatitis by enhancing intestinal barrier integrity and ameliorating PPARα mediated lipotoxicity.
Both live and heat killed Lactiplantibacillus plantarum DPUL-F232 alleviate whey protein-induced food allergy by regulating cellular immunity and repairing the intestinal barrier.
L-Citrulline Ameliorates Iron Metabolism and Mitochondrial Quality Control via Activating AMPK Pathway in Intestine and Improves Microbiota in Mice with Iron Overload.
Oral infection with Porphyromonas gingivalis augmented gingival epithelial barrier molecules alteration with aging.
Zinc lactate alleviates oxidative stress by modulating crosstalk between constitutive androstane receptor signaling pathway and gut microbiota profile in weaned piglets.
Fecal Microbiota Transplantation Attenuates Frailty via Gut-Muscle Axis in Old Mice.
Saccharomyces boulardii alleviates allergic asthma by restoring gut microbiota and metabolic homeostasis via up-regulation of METTL3 in an m6A-dependent manner.
Oat β-glucan repairs the epidermal barrier by upregulating the levels of epidermal differentiation, cell-cell junctions and lipids via Dectin-1.
Effects of electrolyte balance on intestinal barrier, amino acid metabolism, and mTORC1 signaling pathway in piglets fed low-protein diets.
Tedizolid phosphate alleviates DSS-induced ulcerative colitis by inhibiting senescence of cell and colon tissue through activating AMPK signaling pathway.
Elucidating the modulatory role of dietary hydroxyproline on the integrity and functional performance of the intestinal barrier in early-weaned piglets: A comprehensive analysis of its interplay with the gut microbiota and metabolites.
pH Sensitive Quercetin Nanoparticles Ameliorate DSS-Induced Colitis in Mice by Colon-Specific Delivery.
The gut-liver axis perspective: Exploring the protective potential of polysaccharides from Cistanche deserticola against alcoholic liver disease.
Study on the Anti-Ulcerative Colitis Effect of Pseudo-Ginsenoside RT4 Based on Gut Microbiota, Pharmacokinetics, and Tissue Distribution.
Potential effects of sodium hyaluronate on constipation-predominant irritable bowel syndrome.
Splenectomy ameliorates liver cirrhosis by restoring the gut microbiota balance.
Baitouweng decoction repairs the intestinal barrier in DSS-induced colitis mice via regulation of AMPK/mTOR-mediated autophagy.
Gut microbiota dysbiosis and intestinal barrier impairment in diarrhea caused by cold drink and high-fat diet.
Ephrin B3 exacerbates colitis and colitis-associated colorectal cancer.
Ginsenoside Rk3 modulates gut microbiota and regulates immune response of group 3 innate lymphoid cells to against colorectal tumorigenesis.
(-)-Syringaresinol attenuates ulcerative colitis by improving intestinal epithelial barrier function and inhibiting inflammatory responses.
Solobacterium moorei promotes the progression of adenomatous polyps by causing inflammation and disrupting the intestinal barrier.
CAMSAP3, a microtubule orientation regulator, plays a vital role in manifesting differentiation-dependent characteristics in keratinocytes.
Therapeutic potential of Lacticaseibacillus rhamnosus grx10 and its derived postbiotic through gut microbiota and MAPK/MLCK/MLC pathway-mediated intestinal barrier repairment in ulcerative colitis.
Temporal dynamics of neutrophil functions in multiple sclerosis.
Licorice-regulated gut-joint axis for alleviating collagen-induced rheumatoid arthritis.
Paeoniae radix alba improved intestinal mucosal microcirculation disturbance by regulating lncRNA MALAT1/HIF-1α pathway in the treatment of ulcerative colitis.
Silk fibroin microneedles loaded with epigallocatechin gallate mitigate atrazine-induced testicular toxicity.
Xiaoyaosan against depression through suppressing LPS mediated TLR4/NLRP3 signaling pathway in "microbiota-gut-brain" axis.
Polysaccharides, the active component of Dendrobiumofficinale flower, ameliorates chronic pharyngitis in rats via TLR4/NF-κb pathway regulation.
Formononetin ameliorates dextran sulfate sodium-induced colitis via enhancing antioxidant capacity, promoting tight junction protein expression and reshaping M1/M2 macrophage polarization balance.
Efficacy of DHA-enriched phosphatidylserine and its underlying mechanism in alleviating polystyrene nanoplastics-induced hepatotoxicity in mice.
Fructo-oligosaccharides Alleviated Ulcerative Colitis via Gut Microbiota-Dependent Tryptophan Metabolism in Association with Aromatic Hydrocarbon Receptor Activation in Mice.
Chitosan-alginate/R8 ternary polyelectrolyte complex as an oral protein-based vaccine candidate induce effective mucosal immune responses.
Innate lymphoid cell-based immunomodulatory hydrogel microspheres containing Cutibacterium acnes extracellular vesicles for the treatment of psoriasis.
STC2 suppresses triple-negative breast cancer migration and invasion by inhibition on EMT and promotion on cell apoptosis.
Capsaicin combined with cisplatin inhibits TGF-β1-induced EMT and TSCC cells migration via the Claudin-1/PI3K/AKT/mTOR signaling pathway.
Lactobacillus-derived indole derivatives ameliorate intestinal barrier damage in rat pups with complementary food administration.
Integrated Multi-Omics Analysis Reveals Mountain-Cultivated Ginseng Ameliorates Cold-Stimulated Steroid-Resistant Asthma by Regulating Interactions among Microbiota, Genes, and Metabolites.
Dietary rutin improves the antidiarrheal capacity of weaned piglets by improving intestinal barrier function, antioxidant capacity and cecal microbiota composition.
l-Theanine Prevents Colonic Damage via NF-κB/MAPK Signaling Pathways Induced by a High-Fat Diet in Rats.
Anionic polysaccharides benefit the bioavailability of pork myofibrillar protein gels: Evidence from a perspective of protein absorption and metabolism.
L-theanine attenuates H(2)O(2)-induced inflammation and apoptosis in IPEC-J2 cells via inhibiting p38 MAPK signaling pathway.
Lactiplantibacillus plantarum-Derived Indole-3-lactic Acid Ameliorates Intestinal Barrier Integrity through the AhR/Nrf2/NF-κB Axis.
Coptis chinensis and Berberine Ameliorate Chronic Ulcerative Colitis: An Integrated Microbiome-Metabolomics Study.
Indole-3-Aldehyde Reduces Inflammatory Responses and Restores Intestinal Epithelial Barrier Function Partially via Aryl Hydrocarbon Receptor (AhR) in Experimental Colitis Models.
Hazara orthonairovirus nucleoprotein facilitates viral cell-to-cell spread by modulating tight junction protein, claudin-1.
Wnt4 increases the thickness of the epidermis in burn wounds by activating canonical Wnt signalling and decreasing the cell junctions between epidermal cells.
Mitigation of maternal fecal microbiota transplantation on neurobehavioral deficits of offspring rats prenatally exposed to arsenic: Role of microbiota-gut-brain axis.
DUOX2-Induced Oxidative Stress Inhibits Intestinal Angiogenesis through MMP3 in a Low-Birth-Weight Piglet Model.
Resveratrol alleviates DSS-induced IBD in mice by regulating the intestinal microbiota-macrophage-arginine metabolism axis.
Auricularia auricula polysaccharides attenuate obesity in mice through gut commensal Papillibacter cinnamivorans.
Transcriptional Analysis of lncRNA and Target Genes Induced by Influenza A Virus Infection in MDCK Cells.
Role of SIRT2 in intestinal barrier under cold exposure.
Quercetin Attenuates the Combined Effects of Zearalenone and Lipopolysaccharide on IPEC-J2 Cell Injury through Activating the Nrf2 Signaling Pathway.
Green Pea (Pisum sativum L.) Hull Polyphenol Extract Alleviates NAFLD through VB6/TLR4/NF-κB and PPAR Pathways.
Adherent-invasive Escherichia coli LF82 aggravated intestinal inflammation in colitis mice by affecting the gut microbiota and Th17/Treg cell differentiation balance.
The mediation of the AHR/IL-22/STAT3/IL-6 axis by soft-shelled turtle (Pelodiscus sinensis) peptide and Chinese pond turtle (Chinemys reevesii) peptide contributed to their amelioration effects on intestinal mucosal immunity in immunosuppressed mice.
Transcription factor Dmrt1 triggers the SPRY1-NF-κB pathway to maintain testicular immune homeostasis and male fertility.
Polygonum tinctorium leaf extract ameliorates high-fat diet-induced intestinal epithelial damage in mice.
Calcitonin gene-related peptide ameliorates sepsis-induced intestinal injury by suppressing NLRP3 inflammasome activation.
IGFBP2 derived from PO-MSCs promote epithelial barrier destruction by activating FAK signaling in nasal polyps.
Compatibility between cold-natured medicine CP and hot-natured medicine AZ synergistically mitigates colitis mice through attenuating inflammation and restoring gut barrier.
Rabeprazole destroyed gastric epithelial barrier function through FOXF1/STAT3-mediated ZO-1 expression.
Diosmetin Maintains Barrier Integrity by Reducing the Expression of ABCG2 in Colonic Epithelial Cells.
Human umbilical cord mesenchymal stem cells derived exosome shuttling mir-129-5p attenuates inflammatory bowel disease by inhibiting ferroptosis.
Hederacoside C ameliorates colitis via restoring impaired intestinal barrier through moderating S100A9/MAPK and neutrophil recruitment inactivation.
Polysaccharide-rich fractions from Enteromorpha prolifera improve hepatic steatosis and gut barrier integrity in high-fat diet-induced obese mice linking to modulation of gut microbiota.
Subacute Ruminal Acidosis as a Potential Factor that Induces Endometrium Injury in Sheep.
Fecal microbiota transplantation attenuates Escherichia coli infected outgrowth by modulating the intestinal microbiome.
Gegen Qinlian decoction activates AhR/IL-22 to repair intestinal barrier by modulating gut microbiota-related tryptophan metabolism in ulcerative colitis mice.
Dietary pectin attenuates Salmonella typhimurium-induced colitis by modulating the TLR2-NF-κB pathway and intestinal microbiota in mice.
Continuous oral exposure to micro- and nanoplastics induced gut microbiota dysbiosis, intestinal barrier and immune dysfunction in adult mice.
Dual-Targeted Nanoparticle-in-Microparticle System for Ulcerative Colitis Therapy.
Bioconversion of feather waste into bioactive nutrients in water by Bacillus licheniformis WHU.
Potential Toxicity and Mechanisms of T-2 and HT-2 Individually or in Combination on the Intestinal Barrier Function of Porcine Small Intestinal Epithelial Cells.
Bacterial butyrate mediates the anti-atherosclerotic effect of silybin.
Succinate signaling attenuates high-fat diet-induced metabolic disturbance and intestinal barrier dysfunction.
Arula-7 powder improves diarrhea and intestinal epithelial tight junction function associated with its regulation of intestinal flora in calves infected with pathogenic Escherichia coli O(1).
Mechanisms of Lung and Intestinal Microbiota and Innate Immune Changes Caused by Pathogenic Enterococcus Faecalis Promoting the Development of Pediatric Pneumonia.
PA-MSHA Regulates PD-L1 Expression in Hepatoma Cells.
Astragalus polysaccharides alleviate type 1 diabetes via modulating gut microbiota in mice.
Subchronic Microcystin-LR Aggravates Colorectal Inflammatory Response and Barrier Disruption via Raf/ERK Signaling Pathway in Obese Mice.
Morchella esculenta mushroom polysaccharide attenuates diabetes and modulates intestinal permeability and gut microbiota in a type 2 diabetic mice model.
The Protective Effect of Sulforaphane on Dextran Sulfate Sodium-Induced Colitis Depends on Gut Microbial and Nrf2-Related Mechanism.
Honokiol Ameliorates DSS-Induced Mouse Colitis by Inhibiting Inflammation and Oxidative Stress and Improving the Intestinal Barrier.
Knockout of IL-6 mitigates cold water-immersion restraint stress-induced intestinal epithelial injury and apoptosis.
Cassane diterpenoid ameliorates dextran sulfate sodium-induced experimental colitis by regulating gut microbiota and suppressing tryptophan metabolism.
Comprehensive analysis of cuproptosis-related genes in immune infiltration and diagnosis in ulcerative colitis.
Morchella esculenta polysaccharide attenuate obesity, inflammation and modulate gut microbiota.
The Barrier-Enhancing Function of Soluble Yam (Dioscorea opposita Thunb.) Polysaccharides in Rat Intestinal Epithelial Cells as Affected by the Covalent Se Conjugation.
Yajieshaba prevents lipopolysaccharide-induced intestinal barrier injuryanti-inflammatory and anti-apoptosis.
Bisdemethoxycurcumin Alleviates Dextran Sodium Sulfate-Induced Colitis via Inhibiting NLRP3 Inflammasome Activation and Modulating the Gut Microbiota in Mice.
The beneficial effects of Polygonatum sibiricum Red. superfine powder on metabolic hypertensive rats via gut-derived LPS/TLR4 pathway inhibition.
Strains producing different short-chain fatty acids alleviate DSS-induced ulcerative colitis by regulating intestinal microecology.
Apple Polyphenols Improve Intestinal Antioxidant Capacity and Barrier Function by Activating the Nrf2/Keap1 Signaling Pathway in a Pig Model.
Ameloblastin promotes polarization of ameloblast cell lines in a 3-D cell culture system.
The effect of Porphyromonas gingivalis on the gut microbiome of mice in relation to aging.
Effects of betaine on viability, apoptosis, function protein expression and oxidative status in heat-stressed IEC-6 cells.
Glutathione Protects against Paraquat-Induced Oxidative Stress by Regulating Intestinal Barrier, Antioxidant Capacity, and CAR Signaling Pathway in Weaned Piglets.
Aerobic exercise improves intestinal mucosal barrier dysfunction through TLR4/MyD88/NF-κB signaling pathway in diabetic rats.
Fucoidan ameliorates LPS-induced neuronal cell damage and cognitive impairment in mice.
Oxycodone protects cardiac microvascular endothelial cells against ischemia/reperfusion injury by binding to Sigma-1 Receptor.
Postconditioning of stellate ganglion block improves intestinal barrier function by inhibiting autophagy in conscious rats following hemorrhagic shock and resuscitation.
The effects of PIKfyve inhibitor YM201636 on claudins and malignancy potential of nonsmall cell cancer cells.
Gut Microbiota Was Involved in the Process of Liver Injury During Intra-Abdominal Hypertension.
Inhibitor of Differentiation-2 Protein Ameliorates DSS-Induced Ulcerative Colitis by Inhibiting NF-κB Activation in Neutrophils.
Gastrodia remodels intestinal microflora to suppress inflammation in mice with early atherosclerosis.
Li K, Yuan L, Zhang J, Li W, Zhao G, Chen Z, Yang Y, He Z, Xiao P
PloS one 2026;21(1):e0340453
PloS one 2026;21(1):e0340453
Integrating bioinformatic prediction and the "gut microbiota-inflammation-skin axis" to decipher the mechanisms of quercetin (from Evodia rutaecarpa) in diabetic wound healing.
Huang Z, Liu J, Zheng X, Geng X, Tan J, Ai Y, Li H, Zhou D
Frontiers in immunology 2026;17:1755280
Frontiers in immunology 2026;17:1755280
Lactobacillus rhamnosus confers protection against enteropathogenic bacteria by enhancing mucosal immunity and epithelial barrier function.
Gao X, Zhou J, Yan K, Guan Y, Xiang J, Liu Y, Yu H, Wang J, Li Y, Xu Y
Frontiers in cellular and infection microbiology 2026;16:1769889
Frontiers in cellular and infection microbiology 2026;16:1769889
Identification of Key Genes Associated With Epithelial Barrier Dysfunction by Comprehensive Analysis and Experimental Validation.
Liang S, Dong M, Zhu X, Wang S, Lin S, Li Y, Yi S, Wu D, Yang Z, Chen Y, Li J
Allergy 2026 May;81(5):1813-1832
Allergy 2026 May;81(5):1813-1832
Puerarin Improves Glucose and Lipid Metabolism in Type 2 Diabetes by Regulating Gut Microbiota Homeostasis and Promoting Adipose Tissue Thermogenesis.
Cheng L, Gan M, Wang H, Song Y, Bai Y, Zhang D
Phytotherapy research : PTR 2026 May;40(5):2397-2416
Phytotherapy research : PTR 2026 May;40(5):2397-2416
Yeast β-glucan alleviates alcohol-related brain injury by restoring gut-brain axis homeostasis.
Li H, Ouyang Z, Li B, Gong D, Bai J, Li J, Zhang S, Liang Z, Long D
International journal of biological macromolecules 2026 May;360:151880
International journal of biological macromolecules 2026 May;360:151880
Glucuronolactone Promotes Mucin Sulfation to Alleviate Deoxynivalenol-Induced Intestinal Injury via Microbiota-Dependent and -Independent AHR Activation.
Cui C, Zhang B, Tang J, Hou J, Qiu Y, Gao K, Wang L, Jiang Z, Yang X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(25):e22912
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(25):e22912
Effect of Dietary Electrolyte Balance in Low-Protein Diet on Intestinal Barrier, Mitochondrial Function and Carcass Quality of Growing Pigs.
Hao J, Li L, Lin Q, Tu X, Feng J, Ying Y, Ding L, Li J, Hu C
Journal of animal physiology and animal nutrition 2026 May;110(3):388-397
Journal of animal physiology and animal nutrition 2026 May;110(3):388-397
Therapeutic potential of Isatidis Radix alkaloids in RSV pneumonia: A focus on AhR-mediated pulmonary barrier repair.
Xu S, Hou X, Xu Y, Wang X, Xu L, He L
Journal of ethnopharmacology 2026 May 10;362:121387
Journal of ethnopharmacology 2026 May 10;362:121387
Fermented grape pomace alleviates Salmonella typhimurium-induced Hepatointestinal inflammation: FXR mediates protection by orchestrating bile acid homeostasis and suppressing the colonic NLRP3 Inflammasome.
Zhang J, Jiang D, Zhang X, Yang Y, Wu Z
Food research international (Ottawa, Ont.) 2026 May 1;231(Pt 2):118797
Food research international (Ottawa, Ont.) 2026 May 1;231(Pt 2):118797
Scutellaria baicalensis extract prevents metabolic dysfunction-associated steatotic liver disease by modulating the gut-liver axis in high-fat diet mice.
Ma L, Wang Y, Ren T, Pan L, Li X, Wang S, Li D, Zhang M, Li F, Zheng F, Yue H
Phytochemistry 2026 Mar;243:114720
Phytochemistry 2026 Mar;243:114720
Engineered Bacillus subtilis WB600/ZD reduces post-weaning diarrhea in piglets by modulating gut microbiota and aryl hydrocarbon receptor (AHR) signaling.
Li W, Wang X, Zhang Y, Yang H, Wang X, Meng W, Hu T, Zhang W, Zhu Y, Wang J, Yang G
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2026 Mar;24:46-60
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2026 Mar;24:46-60
RAB3B regulates vesicle uptake and tight junction integrity in amniotic epithelial cells and is downregulated in premature rupture of membranes.
Su S, Ye Q, Chen F, Tian Q, Gan C, Li Y
Biology of reproduction 2026 Mar 7;
Biology of reproduction 2026 Mar 7;
Ketogenic diet alleviates septic lung injury via microbial gut-lung axis.
Wei M, Yi X, Lin Z, Cai J, Chen S, Zhou F, Cai H, Lu X, Tang J, Shi Y, Cui L, Yang L, Jing X, Zeng Y, Wu R, Shu T, Li Y, Yang F, He Y, Zhao Z, Yang Y, Zhu W, Jiang Q, Zhang W, Tan X, Ma Z, Fan X, Ma W, Li S, Shu W, Wei H, Xiang Z, Gilbert JA, Gong S, Wang Z
Cell metabolism 2026 Mar 3;38(3):493-511.e12
Cell metabolism 2026 Mar 3;38(3):493-511.e12
Research based on serine metabolism indicates mesenchymal stem cells alleviate psoriasis by regulating the PSPH-PINK1-Parkin-NLRP3 pathway in HaCaT.
Lin Q, Ji Y, Yang B, Zhu R, Song P, Zhao RC
Stem cell research & therapy 2026 Mar 28;17(1)
Stem cell research & therapy 2026 Mar 28;17(1)
Maternal β-hydroxybutyrate during the dry period is associated with altered epithelial cell regulation and rumen morphology of offspring as calves.
Zheng J, Zhang Y, Zhao X, Gai Y, Luo F, Gu Z, Mao S, Ma G, Ghaffari MH, Chen Y
Journal of dairy science 2026 Mar 16;
Journal of dairy science 2026 Mar 16;
Shenqi funeng xingnao prescription regulated the TNF/NOD‒like receptor signaling pathway and brain-gut axis dysfunction caused by exercise-induced fatigue.
Xu D, Zhang W, Tao XR, Gao K, Zhao MN, Wang JW
Journal of ethnopharmacology 2026 Mar 1;358:121035
Journal of ethnopharmacology 2026 Mar 1;358:121035
High fluoride exposure disrupts gut microbiota and induces intestinal barrier damage via RhoA/ROCK-mediated cytoskeletal remodeling.
Wang D, Xin J, Lai C, Sun N, Yang Y, He Y, Duan L, Luo J, He Y, Zhang Y, Zhang Y, Wang H, Zeng D, Bai Y, Ni X
Ecotoxicology and environmental safety 2026 Mar 1;312:119898
Ecotoxicology and environmental safety 2026 Mar 1;312:119898
Rutin targets PD-L1 for the treatment of atopic dermatitis: network pharmacological analysis and experimental evidence.
Wang M, Cheng G, Ma X, Xu H, Sun S, Zhang Y, Jiang W, Chen Q, Li B, Li D, Ma X, Song J
International immunopharmacology 2026 Jun 15;179:116570
International immunopharmacology 2026 Jun 15;179:116570
Unraveling the active ingredients and molecular mechanisms of Qinghua Changyan granule against irritable bowel syndrome with diarrhea: Effects on gut microbiota and glutamine transport via an integrative approach combining UHPLC-MS/MS and experimental verification.
Yang J, Wang Y, Wang S, Liu Z, Chen X, Jia R, Wang J, Wang F, Yang Q, Tang L, Miao W
Fitoterapia 2026 Jan;188:106960
Fitoterapia 2026 Jan;188:106960
Limosilactobacillus reuteri DSM17938 Attenuates Neuroinflammatory Responses After Spinal Cord Injury by Modulating Tryptophan Metabolism.
Cen Q, Cui Y, Feng J, Zhu L, Wei J, Wang L, Chang C, Pang R, Wang J, Zhang A
Probiotics and antimicrobial proteins 2026 Jan;18(1):583-601
Probiotics and antimicrobial proteins 2026 Jan;18(1):583-601
Chrysophanein of Rhubarb rescues ILC3-Derived IL-22 by blocking CCDC25/ILK/HIF-1α for mucosal healing in ulcerative colitis mice.
Xu B, Cao S, Li C, Zhao M, Wang Q, Xie X, Chen H, Xu R, Yi Q, Ke X, Zhu Y, Zhou L, Luo X
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120628
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120628
Ameloblastin Amphipathic Helix Motif mediates Ameloblast Polarization and Prismatic Enamel Formation via a RhoA Signaling Pathway.
Visakan G, Bapat RA, Cai J, Suwandi ET, Joester D, Kegulian NC, Sarkisians E, Aghazadeh M, Webster S, Moradian-Oldak J
Research square 2026 Jan 28;
Research square 2026 Jan 28;
Strategically isolated bacteriophages targeting ETEC K88 (F4) alleviate post-weaning diarrhea in piglets via modulation of gut microbiota and inflammatory responses.
Chen Y, Ding M, Chen X, Zou T, Liu Y, Chen J, You J
Journal of animal science and biotechnology 2026 Jan 18;17(1):11
Journal of animal science and biotechnology 2026 Jan 18;17(1):11
Time-dependent Lactiplantibacillus plantarum (LP) AS21 intervention enhances mesalazine efficacy by modulating gut microbiota and host immunometabolic responses in DSS-induced colitis.
Bacha AS, Ding Z, Li W, Khan I, Ishaq M, Jan AU, Khan A, Chen M, Hanif A, Guo X
Journal of translational medicine 2026 Jan 13;24(1):163
Journal of translational medicine 2026 Jan 13;24(1):163
Effects of Modified Xuanbai Chengqi Decoction against secondary Streptococcus pneumoniae infection following influenza virus infection: A multi-omics analysis.
Yang J, Shi J, Xu W, Mu J, Chang Y, Zhang X, Wang X
Journal of ethnopharmacology 2026 Jan 10;354:120458
Journal of ethnopharmacology 2026 Jan 10;354:120458
Combined metabolomics and gut microbiota analysis reveals the protective effects of α-monoglucosyl rutin against cyclophosphamide-induced intestinal injury.
Tian J, Xiao F, Xu Y, Chen Y, He C, Jiang S, Tang Y
International immunopharmacology 2026 Jan 1;168(Pt 2):115887
International immunopharmacology 2026 Jan 1;168(Pt 2):115887
Gegen Qinlian decoction ameliorates experimental colitis in miceferroptosis pathway.
Jinke H, Jiaqi Z, Zhihong L, Jing MA, Fengyun W, Xudong T
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2026 Feb;46(1):34-38
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2026 Feb;46(1):34-38
Cutibacterium acnes-macrophage fusion membrane coating Cu/Zn-MOF for psoriasis treatment via pathological innate lymphoid cells inhibition.
Zhang J, Gao Y, Le D, Peng Y, Wang H, Lu X, Liu L, Li Y, Wang J, Fan Z, Hu Z, Cheng B, Gan Y, Du L
Materials today. Bio 2026 Feb;36:102731
Materials today. Bio 2026 Feb;36:102731
Genome-wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer.
Wang X, Mi B, Lv J, Tang X, Huang J, Liu F, Xing Y, Wen X, Wang Y, Zhong Y
Oncology letters 2026 Feb;31(2):62
Oncology letters 2026 Feb;31(2):62
DLGAP5 regulates malignancy and lenvatinib sensitivity of hepatocellular carcinoma through AKT/mTOR/NF-κB pathway.
He B, Deng M, Guan R, Mei J, Zou H, Tang Y, Yang Z, Zheng Z, Lin W, Li S, Guo R, Zhao R, Wei W
European journal of medical research 2026 Feb 9;
European journal of medical research 2026 Feb 9;
Anti-Inflammatory Effects of Marine-Derived Resorcylic Acid Lactone Derivatives in Ulcerative Colitis via the MAPK/ERK Pathway.
Zhang X, Mo T, Qin Y, Le M, Tang L, Zhang Z, Yi J, Cen F, Li W, Chen G
Marine drugs 2026 Feb 5;24(2)
Marine drugs 2026 Feb 5;24(2)
A novel role of Dermatophagoides farinae-derived miR-276-3p in aggravating mite-induced allergic airway inflammation.
Zang X, Jiang S, Yu J, Ma L, Mei W, Hong S, Wang W
Microbiology spectrum 2026 Feb 3;14(2):e0192325
Microbiology spectrum 2026 Feb 3;14(2):e0192325
Butyrate ameliorates doxorubicin-induced heart failure by inhibiting cardiomyocyte ferroptosis through the gut-heart axis.
Zeng S, Xie Q, Zhang R, Yang T, Liu D, Zhang J, Ma S, Qiu X
iScience 2026 Feb 20;29(2):114754
iScience 2026 Feb 20;29(2):114754
Integrating serum pharmacochemistry, network pharmacology, gut microbiota and transcriptomic strategies to reveal the active ingredients and mechanism of Changma Xifeng tablet in the treatment of tourette syndrome.
Zhu C, Shi Y, Zhou Z, Shao Y, Wang J, Sun Z, Bian M
Journal of ethnopharmacology 2026 Feb 10;356:120830
Journal of ethnopharmacology 2026 Feb 10;356:120830
Atractylenolide III Alleviates the Lipid Metabolic Disorders in Ovariectomy-Induced Estrogen-Deficient Mice Through Repairing Intestinal Inflammation and Microenvironment.
Yanyan X, Yanyu Q, Qiao G, Jiabo G, Desong K, Heiying J
The journal of obstetrics and gynaecology research 2026 Apr;52(4):e70272
The journal of obstetrics and gynaecology research 2026 Apr;52(4):e70272
Brucea javanica oil emulsion ameliorates ulcerative colitis by upregulating Deoxyribonuclease 2 to suppress cytosolic DNA-sensing signaling.
Ren M, Liu C, Lai J, Huang W, Wang J, Tu J, Yang B, Su Z, Han Q, Lai Z, Chen J, Liang Q, Xie Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157980
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157980
Diabetes Mellitus Facilitates Gallstone Formation Through CXCR2-NETs-Mediated Liver-Bile Barrier Damage.
Shi C, Feng S, Liu T, Meng Z, Zheng Y, Huang Z, Wang T, Zhang B, Xue D, Ma B, Meng X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(24):e19500
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(24):e19500
Neuroprotective Effects of Time-Restricted Feeding Combined With Different Protein Sources in MPTP-Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism.
Li T, Wu J, Zhou SY, Li MA, Zhao LP, Wang A, Song YZ, Huang WY, Tan LL, Qiao CM, Zhao WJ, Cui C, Shen YQ
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(19):e16502
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(19):e16502
Oral Exposure to Polypropylene Microplastics Exacerbates Cow's Milk Allergy in a Murine Model by Skewing the DCs/T-Cell Response toward Th2 Polarization.
Shi Q, Wang Z, Luo H, Chen C, Chen Y, Li X, Xie Y, Zheng S, Meng X, Wu Y, Gao J, Chen H
Journal of agricultural and food chemistry 2026 Apr 22;74(15):12461-12474
Journal of agricultural and food chemistry 2026 Apr 22;74(15):12461-12474
Fucoidan alleviates chemotherapy-induced steatohepatitis by regulating the gut-liver axis.
Cai Y, Chen Y, Bian X, Sun C, Cheng J, Liu H, Jin L, Ma J, Liu W
International immunopharmacology 2026 Apr 15;175:116390
International immunopharmacology 2026 Apr 15;175:116390
Palladium nanozyme loaded metal-organic framework eyedrops alleviate oxidative stress for dry eye treatment.
Wang Y, Chen J, Zhang R, Weng C, Hu D, Jiang W, Zhou Y, Lin Q
Journal of nanobiotechnology 2026 Apr 10;
Journal of nanobiotechnology 2026 Apr 10;
HMGB1 Exacerbates Intestinal Barrier Damage by Inducing Ferroptosis Through the TLR4/NF-κB/GPX4 Pathway in Ulcerative Colitis.
Zhu N, Ge X, Zhang L, Chen X, Xiang W, Mei Q
Mediators of inflammation 2025;2025:2395557
Mediators of inflammation 2025;2025:2395557
Curcumin modulated gut microbiota and alleviated renal fibrosis in 5/6 nephrectomy-induced chronic kidney disease rats.
Li C, Chen X, Yao J, Zha W, Li M, Shen J, Jiang H, Tian P
PloS one 2025;20(1):e0314029
PloS one 2025;20(1):e0314029
SIGIRR Alleviates Intestinal Mucosal Damage in Severe Acute Pancreatitis via the TLR4 Signaling Pathway.
Liu Y, Zhou F, Song Y, Wei S, Cheng B, Liu D, Xiong H, Xie Y, Zhou X
Cellular and molecular gastroenterology and hepatology 2025;19(12):101608
Cellular and molecular gastroenterology and hepatology 2025;19(12):101608
Ginsenoside Reshapes Intestinal Microecology to Alleviate Microgravity Stress.
Wang Y, Chen T, Shi Z, Dong L, Li M, Peng B, Li Q, Pan R, Xiao S, Yang Q, Jiang N, Liu X, Hu Q, Chen Y
Drug design, development and therapy 2025;19:1289-1303
Drug design, development and therapy 2025;19:1289-1303
Network pharmacology-guided investigation of Fuzheng Yanggan Huaxian decoction in a CCL(4)-induced hepatic fibrosis mouse model: involvement of the TLR4-MAPK/NF-κB signaling axis and intestinal barrier.
Ma J, Zang X, Li X, Xu M, Zhang S, Chen X, Zhu T, Luan Y, Chen X, Qiu Y
American journal of translational research 2025;17(9):6795-6810
American journal of translational research 2025;17(9):6795-6810
Deciphering immune cell interaction aberrations in necrotizing enterocolitis: the regulatory role of DHRS7.
Gao K, Chen Y, Lu J, Ge W, Yin Q
Frontiers in immunology 2025;16:1743878
Frontiers in immunology 2025;16:1743878
Berberine-taxifolin co-administration attenuates inflammatory response and intestinal barrier injury via nf-κB/NLRP3 suppression in colitis.
Miao G, Zhang D, Sui Z, Leng J, Deng Y, Gu X, Cao H
Frontiers in immunology 2025;16:1725084
Frontiers in immunology 2025;16:1725084
Modulation of gut microbiota by Gardeniae Fructus oil exerts TLR4/NF-κB/NLRP3 pathway-mediated antidepressant effects based on transcriptomics and fecal transplantation.
Han M, Zhou Y, Gao X, Cheng X, Deng L, Ji S, Li Z, Cai Y, Yan C, Chen Y
Frontiers in pharmacology 2025;16:1635897
Frontiers in pharmacology 2025;16:1635897
Unveiling the neutrophil-Notch2-ISC axis: asiatic acid's therapeutic strategy in infectious colitis.
Zou W, Zhong M, Pei Z, Chen Y, Deng W, Li H
Frontiers in immunology 2025;16:1634063
Frontiers in immunology 2025;16:1634063
Lactobacillus rhamnosus GG attenuates MASLD/MASH progression by modulating gut microbiota and metabolic pathways.
Wang SL, Liang S, Li SY, Fu JW, Wang ZY, Zhu DQ, Chen N
Frontiers in microbiology 2025;16:1586678
Frontiers in microbiology 2025;16:1586678
Vespa orientalis pupae peptide hydrolysates modulate NF-κB signaling in LTA-induced pneumonia from clinical Enterococcus faecalis isolates: implications for gut microbiota.
Rahman MU, Ilyas M, Atta A, Alioui Y, Ali S, Ullah H, Ali M, Deng T, Farooqui NA, Ma R, Abusidu M, Wang J, Wang L, Xin Y
Frontiers in nutrition 2025;12:1651499
Frontiers in nutrition 2025;12:1651499
Effect of four traditional Chinese medicine monomers on mechanical barrier damage and inflammation response of IPEC-J2 cells caused by soybean 7S globulin.
Deng Y, Wu X, Wan Y, Deng J, Deng H
Frontiers in veterinary science 2025;12:1548866
Frontiers in veterinary science 2025;12:1548866
Wendan Decoction exerts therapeutic effects on insomnia by regulating gut microbiota and tryptophan metabolism.
Tian Y, Meng J, Zhang D, Zhai B, Cheng J, Zou J, Shi Y, Guo D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157028
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157028
Zinc Alleviates Gut Barrier Dysfunction by Promoting the Methylation of AKT.
Cai C, Zheng Y, Sun B, Wang G, Li P, Geng H, Li R, Zhu M, Zhu Y, Feng D, Chen L, Chu G, Deng L, Qiao S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(33):e08280
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(33):e08280
Cardamonin alleviates intestinal inflammation in LPS-induced weaned piglets through the AhR/Nrf2/NLRP3 signaling pathway.
Hu X, Fang Y, Zhang Y, Deng T, Ji M, Yang W, Shi L, Xun W
International immunopharmacology 2025 Sep 23;162:115144
International immunopharmacology 2025 Sep 23;162:115144
The deubiquitinase USP2 preserves intestinal barrier through the TRAF6/NF-κB/MLCK/MLC signaling in ulcerative colitis.
Zhou R, Cui Y, Wang W, Qu Y, Zhang G, Wang X, Sun Y, Li J
International immunopharmacology 2025 Sep 23;162:115099
International immunopharmacology 2025 Sep 23;162:115099
Sweroside ameliorates intestinal mucosal microcirculatory disturbances in ulcerative colitis mice by modulating the VEGF and Hippo signaling pathways.
Li D, Chen J, An J, Gu Y, Dong Z, Gao X, Zhang X, Zhang Y
International immunopharmacology 2025 Sep 23;162:115079
International immunopharmacology 2025 Sep 23;162:115079
Lactobacillus plantarum CCFM639 ameliorates vascular dysfunction in mice with Kawasaki disease involving eNOS/NO pathway.
Yu F, Yang T, Zhou Y, Gan T, Zhu Y, Zheng S, Zhou T, Li W, Zhou T
European journal of pharmacology 2025 Sep 15;1003:177877
European journal of pharmacology 2025 Sep 15;1003:177877
Butyrate enhances recovery of chemotherapy-induced oral mucositis by enhancing tight junction protein expression and inhibiting inflammatory responses.
Zeng J, Tan Z, Zhang K, Han Q, Ou S, Wang Z, Liu J, Wang F, Huang Y, Wu L
Medicina oral, patologia oral y cirugia bucal 2025 Sep 1;30(5):e657-e663
Medicina oral, patologia oral y cirugia bucal 2025 Sep 1;30(5):e657-e663
Dendrobium officinale polysaccharide relieves hepatointestinal damage induced by chronic arsenic exposure in chickens by regulating gut microbiota.
Liu Y, Geng H, Han B, Song K, Li J, Ji S, Xue J, Zhang Z
International journal of biological macromolecules 2025 Oct;327(Pt 1):147096
International journal of biological macromolecules 2025 Oct;327(Pt 1):147096
TSP50 in Neural Stem Cells Regulates Aging-Related Cognitive Decline and Neuroinflammation by Altering the Gut Microbiota.
Li X, Chen Y, Gao Z, Liu X, Song Z, Gao F, Wang S, Yu C, Sun L, Huang Y, Zheng L, Wang G, Sun Y, Li J, Yang X, Bao Y
Aging cell 2025 Oct;24(10):e70188
Aging cell 2025 Oct;24(10):e70188
Genetical TRPV4 deletion-associated gut microbiota alleviates cardiac dysfunction in mice with diabetic cardiomyopathy.
Zhou Y, Yang T, Zheng S, Gan T, Yu F, Liu G, Zhou T
Journal of molecular and cellular cardiology 2025 Oct;207:37-50
Journal of molecular and cellular cardiology 2025 Oct;207:37-50
Intestinal Epithelial-Derived USP13 Alleviates Colonic Inflammation by Suppressing GRP78-mediated Endoplasmic Reticulum Stress.
Qian C, Hu C, Xu Y, Xu W, Wang Z, Gan W, Tang W, Huang L, Samorodov AV, Wang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(38):e00741
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(38):e00741
Nuclear receptor Nr1d1 links sleep deprivation to intestinal homeostasis via microbiota-derived taurine.
Wang Z, Zhou L, Zheng Y, Zhong X, Huang R, Sun W, Wang S, Li W
Journal of translational medicine 2025 Oct 15;23(1):1106
Journal of translational medicine 2025 Oct 15;23(1):1106
Psoralen alleviates ulcerative colitis by suppressing inflammation, modulating oxidative stress, and regulating ferroptosis.
Cao L, Tang X, Wang X, Wang Y, Dai W
European journal of pharmacology 2025 Oct 15;1005:178081
European journal of pharmacology 2025 Oct 15;1005:178081
Echinacoside: A potential therapeutic approach for alcohol-related liver disease by alleviating intestinal microbial dysbiosis, intestinal barrier dysfunction, and liver inflammation mediated by the endotoxin-TLR4/NF-κB pathway.
Wang H, Bian Y, Li Y, Yuan Y, Li X, Liu Y, Wang X
European journal of pharmacology 2025 Oct 15;1005:178027
European journal of pharmacology 2025 Oct 15;1005:178027
Oral absorption mechanisms of Astragalus polysaccharides and potential as an excipient to increase the absorption of flavonoids.
Wu X, Xu Y, Zhu D, Zhang W, Yang Y, Feng L, Yang B, Jia X
International journal of biological macromolecules 2025 Nov;330(Pt 2):147977
International journal of biological macromolecules 2025 Nov;330(Pt 2):147977
The effect of anthocyanin extract from Lycium ruthenicum Murray on intestinal barrier function in Bamei ternary pigs.
Wang W, Wu H, Li J, Chen Z, Liu J, Xu E, Hassanin AA, Rahman SU, Chen L, Zheng R
Protoplasma 2025 Nov;262(6):1451-1468
Protoplasma 2025 Nov;262(6):1451-1468
Co-administration of berberine and evodiamine: Mitigating evodiamine-induced hepatotoxicity and potentiating colitis treatment.
Tao X, Gao Y, Jin Z, Lu S, Li Z, Guo S, Fan Q, Li J, Qiao C, Lei H, Zhang Z, Zhao C, Wu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157185
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157185
Bavachinin alleviates allergic rhinitis by modulating gut microbiota and inhibiting NLRP3-mediated epithelial pyroptosis through PI3K/AKT/NF-κB signaling pathway.
Chen T, Dong L, Wu Y, Shen T, Deng Y, Li F, Tao Z
Cellular signalling 2025 Nov;135:112026
Cellular signalling 2025 Nov;135:112026
Autism-Associated Gut Microbiota-Derived Enterococcus facium Modulates Gut-Brain Axis Function and Behavior in Mice.
Ma R, Ullah H, Bohlooli FS, Wen Y, Xin Y, Wang J, Lu S, Wang L
Pathogens (Basel, Switzerland) 2025 Nov 21;14(12)
Pathogens (Basel, Switzerland) 2025 Nov 21;14(12)
Engineering Escherichia coli nissle 1917 with lactonase ZHD101 alleviates zearalenone-induced intestinal disruption and reproductive toxicity in rat.
Dai M, Liu S, Cai R, Li D, Wen Y, Jiang J, Hao N, Wang Q, Gao X
World journal of microbiology & biotechnology 2025 Nov 19;41(12):463
World journal of microbiology & biotechnology 2025 Nov 19;41(12):463
HIF-1α Enhances Intestinal Injury and Inflammation in Severe Acute Pancreatitis Through NLRP3 Inflammasome Activation.
Gao T, Zhang H, Xu Y, He G, Ma H, Zheng C, Li L, Cheng F, Dou H, Zhang F, Zhao H, Qiu Z
Digestive diseases and sciences 2025 May;70(5):1813-1823
Digestive diseases and sciences 2025 May;70(5):1813-1823
Gut commensal Lachnospiraceae bacteria contribute to anti-colitis effects of Lactiplantibacillus plantarum exopolysaccharides.
Yang J, Ren H, Cao J, Fu J, Wang J, Su Z, Lu S, Sheng K, Wang Y
International journal of biological macromolecules 2025 May;309(Pt 1):142815
International journal of biological macromolecules 2025 May;309(Pt 1):142815
Puerarin improves MASLD by remodeling intestinal microenvironment to promote mitochondrial fusion and autophagy.
Sun C, Du M, Sha S, Wang S, Li L, Hou J, Li L, Yuan J, Yan J, Yang Z
Journal of pharmacological sciences 2025 May;158(1):27-41
Journal of pharmacological sciences 2025 May;158(1):27-41
Extracellular Vesicles From Lactobacillus fermentum Enhance Intestinal Barrier Integrity and Restore Gut Microbial Homeostasis in Experimental Murine Colitis.
Wang Y, Li T, Dong Z, Zhang Q, Mi J, Wang Q, Lin G, Ma Q, Jia R, Huang S
The Journal of nutrition 2025 May;155(5):1311-1323
The Journal of nutrition 2025 May;155(5):1311-1323
Drinking Water Temperature Impacts the Pathogenesis of DSS-Induced Ulcerative Colitis by Regulating Intestinal Barrier Function and Remodeling the Gut Microbiota Composition.
Wang H, Yang Y, Li T, Chang S, Zhu Y, Liu C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70645
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70645
Uncovering the molecular mechanisms of tonifying kidney and activating blood Decoction against myocardial fibrosis using network Pharmacology and experimental validation.
Xu R, Bi Y, Ju Y, Yin W, Zhao S, Zhang Y, Zhao X
Scientific reports 2025 May 29;15(1):18912
Scientific reports 2025 May 29;15(1):18912
Atractylenolide-1 Alleviates Ulcerative Colitis via Restraining RhoA/ROCK/MLC Pathway-Mediated Intestinal Barrier Dysfunction.
Gao Z, Yu X, Su W, Huang P, Li Z, Lin Y, Chen LL, Cao Y, Liu Y, Chen J, Yang D, Cao G
Journal of agricultural and food chemistry 2025 May 28;73(21):12690-12701
Journal of agricultural and food chemistry 2025 May 28;73(21):12690-12701
Enhanced alleviation of the selenite-grafted soluble and nondigestive Chinese Yam polysaccharides on nonylphenol-induced cytotoxicity and barrier damage in intestinal epithelial cells.
Wang ZX, Zhang LL, Zhao XH
Scientific reports 2025 May 23;15(1):17970
Scientific reports 2025 May 23;15(1):17970
Garlic-Derived Exosome-Like Nanoparticles Enhance Gut Homeostasis in Stressed Piglets: Involvement of Lactobacillus reuteri Modulation and Indole-3-propionic Acid Induction.
Liu X, Zhang X, Liu H, Fu H, Liu Y, Ge Y, Deng S, Tang Z, Mei L, Wang J, Liu X, Yang Y, Wu Z, Ji Y
Journal of agricultural and food chemistry 2025 Mar 26;73(12):7228-7243
Journal of agricultural and food chemistry 2025 Mar 26;73(12):7228-7243
Fisetin alleviates Salmonella typhimurium-induced colitis through the TLR2/TLR4-NF-κB pathway, regulating microbiota, and repressing intracellular bacterial proliferation by focal adhesion kinase.
Li J, Yang Y, Zhang X, Yang Y, Wu Z
European journal of nutrition 2025 Mar 19;64(3):128
European journal of nutrition 2025 Mar 19;64(3):128
Supplementary Hesperidin Alleviated CPT-11-Induced Diarrhea by Modulating Gut Microbiota and Inhibiting the IL-17 Signaling Pathway.
Zhang X, Yang Y, Wen M, Zhong F, Shu X, Xu R, Xiong P, Zhou Z, He X, Tang X, Wang B, Zhou L, Shen T
Journal of agricultural and food chemistry 2025 Mar 12;73(10):5915-5930
Journal of agricultural and food chemistry 2025 Mar 12;73(10):5915-5930
Why do microplastics aggravate cholestatic liver disease? The NLRP3-mediated intestinal barrier integrity damage matter.
Li S, Yuan Y, Zeng Y, Fang P, Wang J, Liu Y, Xiao F
Environmental pollution (Barking, Essex : 1987) 2025 Mar 1;368:125753
Environmental pollution (Barking, Essex : 1987) 2025 Mar 1;368:125753
Ginsenoside Rh4 inhibits colorectal cancer via the modulation of gut microbiota-mediated bile acid metabolism.
Bai X, Duan Z, Deng J, Zhang Z, Fu R, Zhu C, Fan D
Journal of advanced research 2025 Jun;72:37-52
Journal of advanced research 2025 Jun;72:37-52
Interaction of osteopontin with α-lactalbumin and their synergistic effects in protecting intestinal barrier injury.
He W, Wang X, Zhang J, Cao H, Ren S, Sun X, Yu H, Zhang G, Li C, Liu L, Wang C, He J
Food research international (Ottawa, Ont.) 2025 Jun;211:116513
Food research international (Ottawa, Ont.) 2025 Jun;211:116513
Oleic acid regulates CD4+ T cells differentiation by targeting ODC1-mediated STAT5A phosphorylation in Vogt-Koyanagi-Harada disease.
Liao W, Hu R, Ji Y, Zhong Z, Huang X, Cai T, Zhou C, Wang Y, Ye Z, Yang P
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156660
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156660
Probiotic Combination of Limosilactobacillus fermentum HF07 and Lactococcus lactis HF08 Targeting Gut Microbiota-Secondary Bile Acid Metabolism Ameliorates Inflammation and Intestinal Barrier Dysfunction in Aging Colitis.
Liu X, Guan K, Ma Y, Jiang L, Li Q, Liu Y, Mao K, Wang R
Journal of agricultural and food chemistry 2025 Jun 4;73(22):13439-13454
Journal of agricultural and food chemistry 2025 Jun 4;73(22):13439-13454
Enhancing intestinal epithelial microtubule stability could alleviate IBD symptoms.
Yang F, He Z, Pan X, Xie S, Liang X, Geng L, Xu W, Gong S
Cell communication and signaling : CCS 2025 Jun 4;23(1):263
Cell communication and signaling : CCS 2025 Jun 4;23(1):263
TSP50 deficiency in neural stem cells aggravates colitis in mice by altering intestinal microbiome.
Li X, Jin R, Wang Z, Niu C, Song Z, Liu X, Huang J, Zhang H, Qian X, Gao F, Wang S, Yu C, Sun L, Huang Y, Zheng L, Wang G, Sun Y, Yang X, Bao Y, Li J
NPJ biofilms and microbiomes 2025 Jun 3;11(1):93
NPJ biofilms and microbiomes 2025 Jun 3;11(1):93
Flos lonicerae polysaccharide alleviates inflammatory bowel disease by improving intestinal microbiota and inhibiting oxidative stress and the NF-κB pathway.
Xia Y, Zhou X, Cai P, Yan R, Ocansey DKW, Mao F
International immunopharmacology 2025 Jun 26;159:114956
International immunopharmacology 2025 Jun 26;159:114956
Betulinic Acid Reduces Intestinal Inflammation and Enhances Intestinal Tight Junctions by Modulating the PPAR-γ/NF-κB Signaling Pathway in Intestinal Cells and Organoids.
Zheng X, Cao Z, Wang M, Yuan R, Han Y, Li A, Wang X
Nutrients 2025 Jun 20;17(13)
Nutrients 2025 Jun 20;17(13)
HucMSC-Ex alleviates inflammatory bowel disease by regulating O-GlcNAcylation modification of RACK1 in intestinal epithelial cells.
Liu Z, Yuan J, Din MA, Tian Y, Mao F
Colloids and surfaces. B, Biointerfaces 2025 Jul;251:114606
Colloids and surfaces. B, Biointerfaces 2025 Jul;251:114606
The critical role of Id2 gene in mesenchymal stem cell therapy for colitis through regulating immune response and microbiota.
Wu M, Wang Y, Wei X, Han X, Xu L, Yan D, Li M, Zhong G, Liu Y, Lin J
International immunopharmacology 2025 Jul 28;160:114974
International immunopharmacology 2025 Jul 28;160:114974
An engineered antimicrobial peptide Z-FV7 demonstrates bactericidal efficacy against multidrug-resistant Escherichia coli in a murine model of endometritis.
Su J, Yang H, Wang S, Wang X, Li W, Meng W, Sun J, Zhu Y
Veterinary research 2025 Jul 25;56(1):159
Veterinary research 2025 Jul 25;56(1):159
Gentiopicroside improves DSS-induced ulcerative colitis and secondary liver injury in mice by enhancing the intestinal barrier and regulating the gut microbiome.
Cao L, Niu M, Tang X, Wang Y, Hu X, Dai W
Scientific reports 2025 Jul 25;15(1):27159
Scientific reports 2025 Jul 25;15(1):27159
Protective effect of a novel nonsteroidal organoselenium compound SLL-1-43 on ulcerative colitis through down-regulating NOX2 signaling pathway in vitro and in vivo.
Chen L, Pang W, Luo X, Li T, Ju Q, Yang Z, He X, Li X, Ge Y, Bi X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156899
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156899
Terrestrosin D promotes autophagy and apoptosis of breast cancer cells through PSMD1-dependent activation of P53 pathway.
Jia LL, Wu CJ, Ye PW, Zhang Q, Liu H, Li TP, Hu XL
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156883
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156883
Changdiqing decoction (CDQD) ameliorates colitis via suppressing inflammatory macrophage activation and modulating gut microbiota.
Lin Z, Wang J, Luo H, Huang L, Pan Z, Yang S, Zhong C, Shan NC, Ye Z, Tan H, Yang X, Zhang B, Huang C, Zhang H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156856
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156856
Exploring the Mechanism of Kidney Injury in Mice Induced by High-Fat Diet and Polystyrene Nanoplastics Co-Exposure Through the Kidney-Gut Axis.
Dong J, Yang F, Xu Y, Zhao Q, Li X, Liu T, Tang Y
Journal of agricultural and food chemistry 2025 Jul 16;73(28):17956-17966
Journal of agricultural and food chemistry 2025 Jul 16;73(28):17956-17966
Tryptophan-Rich Diet Improves High-Fat Diet-Induced Cognitive Dysfunction and Blood-Brain Barrier Disruption in C57BL/6 Mice through FFAR3 Activation.
Pan C, Wang J, Mao Z, Jiang X, Xu Y, Zhang Y, Chen L, Zhang ZY, Wang X
Journal of agricultural and food chemistry 2025 Jul 16;73(28):17696-17712
Journal of agricultural and food chemistry 2025 Jul 16;73(28):17696-17712
Biological and metabolomic insights into RACGAP1-mediated growth and progression of clear cell renal cell carcinoma.
Li W, Gan L, Zang W, Chen Y, Xu B
American journal of physiology. Cell physiology 2025 Jul 1;329(1):C283-C297
American journal of physiology. Cell physiology 2025 Jul 1;329(1):C283-C297
Maternal lead exposure impairs offspring growth and intestinal microbiota via AMPK/ULK1 pathway activation.
He Y, Wang M, An M, Kulyar MF, Li M, Xu H, Wang Y
Ecotoxicology and environmental safety 2025 Jul 1;299:118345
Ecotoxicology and environmental safety 2025 Jul 1;299:118345
Luteolin Alleviates Ulcerative Colitis in Mice by Modulating Gut Microbiota and Plasma Metabolism.
Yang S, Duan H, Yan Z, Xue C, Niu T, Cheng W, Zhang Y, Zhao X, Hu J, Zhang L
Nutrients 2025 Jan 7;17(2)
Nutrients 2025 Jan 7;17(2)
The effects of rosmarinic acid and antibiotics on the intestinal morphology, function, and cecal microbiota of broiler chickens.
Ding X, Wang J, Zhu W
Journal of animal science 2025 Jan 4;103
Journal of animal science 2025 Jan 4;103
Cimicifuga heracleifolia kom. Attenuates ulcerative colitis through the PI3K/AKT/NF-κB signaling pathway.
Wu XY, Dong QW, Zhang YB, Li JX, Zhang MQ, Zhang DQ, Cui YL
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):118892
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):118892
A comparative study on in vitro models of necrotizing enterocolitis induced by single and combined stimulation.
Gao C, Feng Z, Wang L, Fu K, Yang Z, Wang S, Yu S
Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology 2025 Feb;26(1):62-66
Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology 2025 Feb;26(1):62-66
Engineered Bacillus subtilis WB600/ZD prevents Salmonella Infantis-induced intestinal inflammation and alters the colon microbiota in a mouse model.
Li W, Wang X, Chen K, Zhu Y, Yang G, Jin Y, Wang J
Veterinary research 2025 Feb 8;56(1):35
Veterinary research 2025 Feb 8;56(1):35
Notch/IL33/ST2 signaling was involved in the maintenance of intestinal epithelial barrier through regulating tight junction after LPS stimulation.
Zhang Y, Xu C, Li F, Chen G
Cellular and molecular biology (Noisy-le-Grand, France) 2025 Feb 20;71(2):36-42
Cellular and molecular biology (Noisy-le-Grand, France) 2025 Feb 20;71(2):36-42
Brown Algae Polysaccharides Alleviate Diquat-Induced Oxidative Stress in Piglets and IPEC-J2 Cells via Nrf2/ARE Signaling Pathway.
Hou C, Yu Z, Shi C, Huang Y, Liu H
Animals : an open access journal from MDPI 2025 Feb 14;15(4)
Animals : an open access journal from MDPI 2025 Feb 14;15(4)
Dihydromyricetin/montmorillonite intercalation compounds ameliorates DSS-induced colitis: Role of intestinal epithelial barrier, NLRP3 inflammasome pathway and gut microbiota.
Jiang L, Ma X, Yan Q, Pu D, Fu X, Zhang D
International journal of pharmaceutics 2025 Feb 10;670:125155
International journal of pharmaceutics 2025 Feb 10;670:125155
Berberine Prevents NSAID-Induced Small Intestinal Injury by Protecting Intestinal Barrier and Inhibiting Inflammasome-Associated Activation.
Ishiguro M, Takahara M, Takaki A, Hiraoka S, Toyosawa J, Aoyama Y, Igawa S, Yamasaki Y, Inokuchi T, Kinugasa H, Otsuka M
Digestive diseases and sciences 2025 Dec;70(12):4140-4151
Digestive diseases and sciences 2025 Dec;70(12):4140-4151
EUK nanozyme-loaded PL&GA coacervate droplets attenuate ulcerative colitis through restoring gut homeostasis and restricting intestinal cell ferroptosis.
Zhou M, Lu L, Xu X, Zhou Y, Fang H, Wang X, Li D, Li X, Hua J, Liu J, Li Y, Jiang L, Miao Q, Wen H, He J, Yang S
Materials today. Bio 2025 Dec;35:102466
Materials today. Bio 2025 Dec;35:102466
Probiotic-based self-crosslinking bio-coating for the treatment of colitis by increasing probiotic colonization.
Shi S, Li B, Zhang Y, Li Z, Cui Y, Ma C, Zhang X, Liu S, Zhou B
Materials today. Bio 2025 Dec;35:102447
Materials today. Bio 2025 Dec;35:102447
Co-fermentation of honeysuckle-Cassia seeds by Lactobacillus acidophilus and Bacillus subtilis: A new approach to attenuate alcohol-induced acute gastric mucosal damage and modulate immune response.
Zhou M, Cao X, Ji H, Liu Z, Guo H, Zhang Y, Huang Y, Wang F, Pang M, Wei Y
Food research international (Ottawa, Ont.) 2025 Dec;222(Pt 1):117639
Food research international (Ottawa, Ont.) 2025 Dec;222(Pt 1):117639
Physical prehabilitation improves colonic anastomosis healing in a malnourished rat model only if attached to effective nutritional prehabilitation - Experimental study.
Lévay K, Kovács S, Budai A, Horváth I, Kovács N, Máthé D, Szigeti K, Dunai Z, Makra N, Juhász J, Ostorházi E, Bánky B, Szijártó A, Fülöp A
Surgery 2025 Dec;188:109677
Surgery 2025 Dec;188:109677
Formononetin and daidzein from Huoxiangzhengqi formula ameliorate Salmonella Typhimurium-induced intestinal flora dysbiosis and barrier dysfunction.
Li Z, Wan F, Zhang N, Xiong H, Song T, Mei Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157465
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157465
Secondary Bile Acids Modified by Odoribacter Splanchnicus Alleviate Colitis by Suppressing Neutrophil Extracellular Trap Formation.
Xu J, Li J, Guo X, Huang C, Peng Y, Xu H, Li Y, Xu J, Hu J, Liao Y, Nie Y, Zhou Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e09073
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e09073
Qula-derived Limosilactobacillus fermentum TD-3 and Lactococcus lactis MQ1-1 alleviate aging-related intestinal barrier dysfunction via microbiota-short-chain fatty acid-AMPK/MLCK-tight junction axis.
Liu X, Guan K, Liu C, Sun Y, Ma Y, Mao K, Li Q, Wang R, Lu W
Journal of dairy science 2025 Dec;108(12):12949-12969
Journal of dairy science 2025 Dec;108(12):12949-12969
Nanozymes modulate probiotic tryptophan metabolism to prevent Salmonella infection in mammalian models.
Lin Z, Feng Y, Chen L, Wang J, Wang Q, Cao H, Gao Y, Wang L, Zhang Y, Jiang J, Gao L, Dong B
Nature microbiology 2025 Dec;10(12):3272-3289
Nature microbiology 2025 Dec;10(12):3272-3289
Pharmacokinetic and Pharmacodynamic Evaluation of PZ-2891, an Anti-Alzheimer's Disease Agonist of PANK2.
Chen Y, Ma H, Jin M, Zhang S, Qu S, Wang G, Aa J
Pharmaceuticals (Basel, Switzerland) 2025 Dec 9;18(12)
Pharmaceuticals (Basel, Switzerland) 2025 Dec 9;18(12)
Nicotine exacerbates MASH via inducing intestinal dysbiosis and barrier dysfunction.
Yi F, Wang J, Chen Y, Xia Y, Zhou H, Huang Y, Shen Y, Fang S, Wang X, Zhang Y, Chen Y, Chen D
Communications biology 2025 Dec 5;8(1):1748
Communications biology 2025 Dec 5;8(1):1748
The Effect of 2'-Fucosyllactose on Gut Health in Aged Mice.
Jiang S, Li Y, Luo T, Huang Y, Che H, Pang J, Meng X
Foods (Basel, Switzerland) 2025 Dec 5;14(24)
Foods (Basel, Switzerland) 2025 Dec 5;14(24)
Quercetin alleviates ulcerative colitis via regulating gut microbiota and tryptophan metabolism.
Xiong M, Kuang W, Liu Z, Tong R, Deng X, Wang N, Wan X, Feng M, Luo Y, Zhang B, Zhang Z, Zheng F
mSystems 2025 Dec 17;10(12):e0070325
mSystems 2025 Dec 17;10(12):e0070325
Nano-functionalized probiotic treats atherosclerosis via inhibiting intestinal microbiota-TMA-TMAO axis.
Chen Z, Zhu Q, Xu H, Hu Y, Wang Y, Chen Z, Wang Y, Huang X, Fu G, Ma B, Zhang W
Nature communications 2025 Dec 13;16(1):11294
Nature communications 2025 Dec 13;16(1):11294
The Hormonal Effect of Fibroblast Growth Factor 19 on the Intestinal Adaptation in Pediatric Short Bowel Syndrome: An in Vitro Study Using Patients-Derived Enteroids.
Gong Y, Wang Y, Zhao Y, Yan J, Zhang T
Journal of pediatric surgery 2025 Aug;60(8):162387
Journal of pediatric surgery 2025 Aug;60(8):162387
Chronic Arsenic Exposure Causes Alzheimer's Disease Characteristic Effects and the Intervention of Fecal Microbiota Transplantation in Rats.
Li S, Li J, Chen K, Wang J, Wang L, Feng C, Wang K, Xu Y, Gao Y, Yan X, Zhao Q, Li B, Qiu Y
Journal of applied toxicology : JAT 2025 Aug;45(8):1476-1486
Journal of applied toxicology : JAT 2025 Aug;45(8):1476-1486
Apigenin mitigates intestinal barrier dysfunction in sepsis by modulating the AKT signaling pathway.
Lijun Z, Liping W, Dandan Z, Wenjie Z, Renjie X, Xueyan J, Wenqing C, Chen L, Lu Z
BMC gastroenterology 2025 Aug 30;25(1):626
BMC gastroenterology 2025 Aug 30;25(1):626
β-Nicotinamide mononucleotide alleviates Alcohol-Induced liver injury in a mouse model through activation of NAD(+)/SIRT1 signaling pathways.
Yang X, Zheng E, Lin Y, Sun H, Zhang J, Yu Y
Hereditas 2025 Aug 16;162(1):161
Hereditas 2025 Aug 16;162(1):161
Flavonoid Extract of Senecio scandens Buch.-Ham. Ameliorates CTX-Induced Immunosuppression and Intestinal Damage via Activating the MyD88-Mediated Nuclear Factor-κB Signaling Pathway.
Zhu X, Zhang L, Ni X, Guo J, Fang Y, Xu J, Chen Z, Hao Z
Nutrients 2025 Aug 1;17(15)
Nutrients 2025 Aug 1;17(15)
Modulation of Intestinal Barrier Function and Wnt/β- Catenin Pathway by Sanzi Formula in Colorectal Adenoma Development.
Peng W, Li Z, Zou S, Li H, Tian Y, Hua Y, Wei L, Zhang Z, Gu Y, Xu T
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 2025 Apr 7;36(9):547-555
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 2025 Apr 7;36(9):547-555
Covalent Grafting of Inorganic Selenium to the Water-Soluble and Nondigestive Chinese Yam Polysaccharides Causes Greater Protection of IEC-6 Cells with Acrylamide Injury.
Wang ZX, Zhang LL, Zhao XH
Foods (Basel, Switzerland) 2025 Apr 29;14(9)
Foods (Basel, Switzerland) 2025 Apr 29;14(9)
Card9 deficiency exacerbates vulvovaginal candidiasis by impairing the IL-17 production and vaginal epithelial barrier.
Liu W, Song Y, Wang R, Wan Z, Li R, Wang X
Medical mycology 2025 Apr 2;63(4)
Medical mycology 2025 Apr 2;63(4)
Green Tea Ameliorates Depression-Like Behavior and Cognitive Impairment Induced by High-Fat Diet and Chronic Mild Stress.
Fan M, Jiang Y, Cai C, Wang Z, Chen L, Hu S, Zhang X, Yin H, Qian Z, Huang S, Yang J
Phytotherapy research : PTR 2025 Apr 17;
Phytotherapy research : PTR 2025 Apr 17;
Statin therapy associated Lactobacillus intestinalis attenuates pancreatic fibrosis through remodeling intestinal homeostasis.
Sui Y, Zhang T, Ou S, Li G, Liu L, Lu T, Zhang C, Cao Y, Bai R, Zhou H, Zhao X, Yuan Y, Wang G, Chen H, Kong R, Sun B, Li L
NPJ biofilms and microbiomes 2025 Apr 15;11(1):59
NPJ biofilms and microbiomes 2025 Apr 15;11(1):59
Overexpression of Plakophilin2 Mitigates Capillary Leak Syndrome in Severe Acute Pancreatitis by Activating the p38/MAPK Signaling Pathway.
Liu H, Xu X, Li J, Liu Z, Xiong Y, Yue M, Liu P
Journal of inflammation research 2024;17:4129-4149
Journal of inflammation research 2024;17:4129-4149
Effects of hydroxychloroquine on the mucosal barrier and gut microbiota during healing of mice colitis.
Huang P, Zhou Y, Wang S, Qian X, Ren C, Zhou Z
American journal of translational research 2024;16(8):4144-4153
American journal of translational research 2024;16(8):4144-4153
HucMSC-Ex alleviates DSS-induced colitis in mice by decreasing mast cell activation via the IL-33/ST2 axis.
Wei Z, Tang X, Yi C, Ocansey DKW, Mao F, Mao Z
American journal of translational research 2024;16(6):2727-2744
American journal of translational research 2024;16(6):2727-2744
Human umbilical cord mesenchymal stem cells derived-exosomes alleviate LPS-induced cervical inflammation and epithelial-mesenchymal transition.
Yi C, Wang H, Din MAU, Xia Y, Akanyibah FA, Mao F
American journal of translational research 2024;16(11):6903-6913
American journal of translational research 2024;16(11):6903-6913
Bacteroides fragilis capsular polysaccharide A ameliorates ulcerative colitis in rat by recovering intestinal barrier integrity and restoring gut microbiota.
Zhong Y, Chang X, Zhao Z, Zheng L, Kuang G, Li P, Liu C, Fan Y, Liang Z, Zhuang K, Xie Q, Liu Y
Frontiers in pharmacology 2024;15:1402465
Frontiers in pharmacology 2024;15:1402465
Circadian rhythm disruption-mediated downregulation of Bmal1 exacerbates DSS-induced colitis by impairing intestinal barrier.
Zhang Z, Li W, Han X, Tian D, Yan W, Liu M, Cao L
Frontiers in immunology 2024;15:1402395
Frontiers in immunology 2024;15:1402395
Hinesol attenuates DSS-induced ulcerative colitis through the suppression of Src-mediated NF-κB and chemokine signaling pathway.
Li YX, Liu J, Li F
Cell biochemistry and biophysics 2024 Sep;82(3):2747-2757
Cell biochemistry and biophysics 2024 Sep;82(3):2747-2757
Carbon monoxide-releasing molecule-3 exerts neuroprotection effects after cardiac arrest in mice: A randomized controlled study.
Zhao Y, Yao Z, Lu L, Xu S, Sun J, Zhu Y, Wu Y, Yu Z
Resuscitation plus 2024 Sep;19:100703
Resuscitation plus 2024 Sep;19:100703
Dihydroartemisinin Modulates Enteric Glial Cell Heterogeneity to Alleviate Colitis.
Qiu P, Chang Y, Chen X, Wang S, Nie H, Hong Y, Zhang M, Wang H, Xiao C, Chen Y, Liu L, Zhao Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(35):e2403461
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(35):e2403461
miR-155 induces sepsis-associated damage to the intestinal mucosal barrier via sirtuin 1/nuclear factor-κB-mediated intestinal pyroptosis.
Li Z, Wang Y, Huang W, Shi X, Ma T, Yu X
Acta biochimica et biophysica Sinica 2024 Sep 9;56(11):1618-1632
Acta biochimica et biophysica Sinica 2024 Sep 9;56(11):1618-1632
Exploring the efficacy and mechanism of Bailing capsule to improve polycystic ovary syndrome in mice based on intestinal-derived LPS-TLR4 pathway.
Guan HR, Li B, Zhang ZH, Wu HS, Wang N, Chen XF, Zhou CL, Bian XR, Li L, Xu WF, He XL, Dong YJ, Jiang NH, Su J, Lv GY, Chen SH
Journal of ethnopharmacology 2024 Sep 15;331:118274
Journal of ethnopharmacology 2024 Sep 15;331:118274
Integrating metagenomics with metabolomics for gut microbiota and metabolites profiling in acute pancreatitis.
Jia Y, Shi Y, Wang J, Liu H, Huang Y, Wang H, Liu Y, Peng J
Scientific reports 2024 Sep 14;14(1):21491
Scientific reports 2024 Sep 14;14(1):21491
Anemarrhena asphodeloides Bunge polysaccharides alleviate lipoteichoic acid-induced lung inflammation and modulate gut microbiota in mice.
Wen Y, Ullah H, Ma R, Farooqui NA, Li J, Alioui Y, Qiu J
Heliyon 2024 Oct 30;10(20):e39390
Heliyon 2024 Oct 30;10(20):e39390
DHA-enriched phosphatidylserine ameliorates cyclophosphamide-induced liver injury via regulating the gut-liver axis.
Zhang H, Lu Y, Zhang Y, Dong J, Jiang S, Tang Y
International immunopharmacology 2024 Oct 25;140:112895
International immunopharmacology 2024 Oct 25;140:112895
Involvement of gut microbiota recovery and autophagy induction in Youhua Kuijie formula's protection against experimental ulcerative colitis.
Sheng T, Wang L, Yan S, Wei Q, Geng X, Lan W, Chen Y, Liu Y, Li N
Experimental animals 2024 Oct 23;73(4):357-369
Experimental animals 2024 Oct 23;73(4):357-369
Goat Milk Exosomes Ameliorate Ulcerative Colitis in Mice through Modulation of the Intestinal Barrier, Gut Microbiota, and Metabolites.
Gao F, Wu S, Zhang K, Xu Z, Zhang X, Zhu Z, Quan F
Journal of agricultural and food chemistry 2024 Oct 23;72(42):23196-23210
Journal of agricultural and food chemistry 2024 Oct 23;72(42):23196-23210
Ferulic Acid Inhibits Arsenic-Induced Colon Injury by Improving Intestinal Barrier Function.
Wang S, Hong Y, Li Y, Zhang Z, Han J, Yang Z, Yang Y, Ma Z, Wang Q
Environmental toxicology 2024 Nov;39(11):4821-4831
Environmental toxicology 2024 Nov;39(11):4821-4831
Goat milk derived small extracellular vesicles ameliorate LPS-induced intestinal epithelial barrier dysfunction, oxidative stress, and apoptosis by inhibiting the MAPK signaling pathway.
Gao F, Zhang X, Xu Z, Zhang K, Quan F
Food & function 2024 Nov 25;15(23):11590-11607
Food & function 2024 Nov 25;15(23):11590-11607
Ginsenoside Rg1 Alleviates Blood-Milk Barrier Disruption in Subclinical Bovine Mastitis by Regulating Oxidative Stress-Induced Excessive Autophagy.
Yang S, Fang Z, Duan H, Dong W, Xiao L
Antioxidants (Basel, Switzerland) 2024 Nov 24;13(12)
Antioxidants (Basel, Switzerland) 2024 Nov 24;13(12)
Multiomics profiling uncovers curdione-induced reproductive toxicity in HTR-8/SVneo cells.
Wu Q, Chen M, Lin Y, Zhang J, Gao X, Wu Y, Wu C, Wen J, Li J, Li C, Bao W, Zhang D, Zheng M, Zhu A
Heliyon 2024 Nov 15;10(21):e38650
Heliyon 2024 Nov 15;10(21):e38650
TIPE2 aggravates experimental colitis and disrupts intestinal epithelial barrier integrity by activating JAK2/STAT3/SOCS3 signal pathway.
Zeng L, Wang Y, Shen J, Wei X, Wu Y, Chi X, Zheng X, Yu X, Shi Y, Liu W
Experimental cell research 2024 Nov 1;443(1):114287
Experimental cell research 2024 Nov 1;443(1):114287
Dapagliflozin ameliorates hepatic steatosis via suppressing LXRα-mediated synthesis of lipids and bile acids.
Jin Z, Yin R, Yuan Y, Zheng C, Zhang P, Wang Y, Weng H
Biochemical pharmacology 2024 May;223:116167
Biochemical pharmacology 2024 May;223:116167
Inhibition of piezo1 prevents chronic cerebral hypoperfusion-induced cognitive impairment and blood brain barrier disruption.
Xu F, Xin Q, Ren M, Shi P, Wang B
Neurochemistry international 2024 May;175:105702
Neurochemistry international 2024 May;175:105702
Integrating Epigenetics, Proteomics, and Metabolomics to Reveal the Involvement of Wnt/β-Catenin Signaling Pathway in Oridonin-Induced Reproductive Toxicity.
Wu Q, Gao X, Lin Y, Wu C, Zhang J, Chen M, Wen J, Wu Y, Tian K, Bao W, Sun P, Zhu A
Toxics 2024 May 7;12(5)
Toxics 2024 May 7;12(5)
Lycium barbarum polysaccharide remodels colon inflammatory microenvironment and improves gut health.
Li R, Yang P, Liu B, Ye Z, Zhang P, Li M, Gong Y, Huang Y, Yang L, Li M
Heliyon 2024 May 30;10(10):e30594
Heliyon 2024 May 30;10(10):e30594
Chaihu Guizhi Ganjiang Decoction attenuates nonalcoholic steatohepatitis by enhancing intestinal barrier integrity and ameliorating PPARα mediated lipotoxicity.
Wu H, Lou T, Pan M, Wei Z, Yang X, Liu L, Feng M, Shi L, Qu B, Cong S, Chen K, Yang H, Liu J, Li Y, Jia Z, Xiao H
Journal of ethnopharmacology 2024 May 23;326:117841
Journal of ethnopharmacology 2024 May 23;326:117841
Both live and heat killed Lactiplantibacillus plantarum DPUL-F232 alleviate whey protein-induced food allergy by regulating cellular immunity and repairing the intestinal barrier.
Feng L, Chen G, Guo Z, Yao W, Li X, Mu G, Zhu X
Food & function 2024 May 20;15(10):5496-5509
Food & function 2024 May 20;15(10):5496-5509
L-Citrulline Ameliorates Iron Metabolism and Mitochondrial Quality Control via Activating AMPK Pathway in Intestine and Improves Microbiota in Mice with Iron Overload.
Zhao D, Gao Y, Chen Y, Zhang Y, Deng Y, Niu S, Dai H
Molecular nutrition & food research 2024 Mar;68(6):e2300723
Molecular nutrition & food research 2024 Mar;68(6):e2300723
Oral infection with Porphyromonas gingivalis augmented gingival epithelial barrier molecules alteration with aging.
Giri S, Takada A, Paudel D, Uehara O, Kurashige Y, Kuramitsu Y, Furukawa M, Matsushita K, Arakawa T, Nagasawa T, Abiko Y, Furuichi Y
Journal of oral biosciences 2024 Mar;66(1):126-133
Journal of oral biosciences 2024 Mar;66(1):126-133
Zinc lactate alleviates oxidative stress by modulating crosstalk between constitutive androstane receptor signaling pathway and gut microbiota profile in weaned piglets.
Tang W, Xiang X, Wang H, Zhou W, He L, Yin Y, Li T
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2024 Mar;16:23-33
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2024 Mar;16:23-33
Fecal Microbiota Transplantation Attenuates Frailty via Gut-Muscle Axis in Old Mice.
Zhu M, Huang Y, Wang Z, Jin Z, Cao J, Zhong Q, Xiong Z
Aging and disease 2024 Mar 21;16(2):1180-1198
Aging and disease 2024 Mar 21;16(2):1180-1198
Saccharomyces boulardii alleviates allergic asthma by restoring gut microbiota and metabolic homeostasis via up-regulation of METTL3 in an m6A-dependent manner.
Liu D, Hu L, Yang Y, Wang Y, Li Y, Su J, Wang G, Gong S
Immunology letters 2024 Jun;267:106853
Immunology letters 2024 Jun;267:106853
Oat β-glucan repairs the epidermal barrier by upregulating the levels of epidermal differentiation, cell-cell junctions and lipids via Dectin-1.
Jing R, Fu M, Huang Y, Zhang K, Ye J, Gong F, Jihea Ali Naji Nasser AB, Xu X, Xiao J, Yu G, Lin S, Zhao W, Xu N, Li X, Li Z, Gao S
British journal of pharmacology 2024 Jun;181(11):1596-1613
British journal of pharmacology 2024 Jun;181(11):1596-1613
Effects of electrolyte balance on intestinal barrier, amino acid metabolism, and mTORC1 signaling pathway in piglets fed low-protein diets.
Lin Q, Tu X, Li X, Gou F, Ding L, Lu Z, Feng J, Ying Y, Hu C
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2024 Jun;17:408-417
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2024 Jun;17:408-417
Tedizolid phosphate alleviates DSS-induced ulcerative colitis by inhibiting senescence of cell and colon tissue through activating AMPK signaling pathway.
Zhou M, Liu ZL, Liu JY, Wang XB
International immunopharmacology 2024 Jun 30;135:112286
International immunopharmacology 2024 Jun 30;135:112286
Elucidating the modulatory role of dietary hydroxyproline on the integrity and functional performance of the intestinal barrier in early-weaned piglets: A comprehensive analysis of its interplay with the gut microbiota and metabolites.
Tang Z, Yang Y, Yang M, Jiang D, Ge Y, Zhang X, Liu H, Fu Q, Liu X, Yang Y, Wu Z, Ji Y
International immunopharmacology 2024 Jun 15;134:112268
International immunopharmacology 2024 Jun 15;134:112268
pH Sensitive Quercetin Nanoparticles Ameliorate DSS-Induced Colitis in Mice by Colon-Specific Delivery.
Wang L, Fu R, Meng Y, Liang J, Xue W, Hu H, Meng J, Zhang M
Molecular nutrition & food research 2024 Jan;68(2):e2300051
Molecular nutrition & food research 2024 Jan;68(2):e2300051
The gut-liver axis perspective: Exploring the protective potential of polysaccharides from Cistanche deserticola against alcoholic liver disease.
Wang H, Yan J, Wang K, Liu Y, Liu S, Wu K, Wang X, Haider A, Liu Y, Zhou Q, Wang X
International journal of biological macromolecules 2024 Jan;256(Pt 1):128394
International journal of biological macromolecules 2024 Jan;256(Pt 1):128394
Study on the Anti-Ulcerative Colitis Effect of Pseudo-Ginsenoside RT4 Based on Gut Microbiota, Pharmacokinetics, and Tissue Distribution.
Yu H, Wang C, Wu J, Wang Q, Liu H, Li Z, He S, Wang C, Liu J
International journal of molecular sciences 2024 Jan 9;25(2)
International journal of molecular sciences 2024 Jan 9;25(2)
Potential effects of sodium hyaluronate on constipation-predominant irritable bowel syndrome.
Cui L, Zou S, Liu J, Lv H, Li H, Zhang Z
International immunopharmacology 2024 Jan 25;127:111404
International immunopharmacology 2024 Jan 25;127:111404
Splenectomy ameliorates liver cirrhosis by restoring the gut microbiota balance.
Jin Y, Shi M, Feng J, Zhang Z, Zhao B, Li Q, Yu L, Lu Z
Cellular and molecular life sciences : CMLS 2024 Jan 12;81(1):32
Cellular and molecular life sciences : CMLS 2024 Jan 12;81(1):32
Baitouweng decoction repairs the intestinal barrier in DSS-induced colitis mice via regulation of AMPK/mTOR-mediated autophagy.
Pan SM, Wang CL, Hu ZF, Zhang ML, Pan ZF, Zhou RY, Wang XJ, Huang SW, Li YY, Wang Q, Luo X, Zhou L, Hou JT, Chen B
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116888
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116888
Gut microbiota dysbiosis and intestinal barrier impairment in diarrhea caused by cold drink and high-fat diet.
Tian Y, Fu M, Su J, Yan M, Yu J, Wang C, Niu Z, Du Y, Hu X, Zheng J, Tao B, Gao Z, Chen J, Chen S, Lv G
Toxicology 2024 Feb;502:153728
Toxicology 2024 Feb;502:153728
Ephrin B3 exacerbates colitis and colitis-associated colorectal cancer.
Qiao Z, Liao M, Xiao M, Luo S, Wang K, Niu M, Jiang H, Sun S, Xu G, Xu N, Xu Q, Liu Y
Biochemical pharmacology 2024 Feb;220:116004
Biochemical pharmacology 2024 Feb;220:116004
Ginsenoside Rk3 modulates gut microbiota and regulates immune response of group 3 innate lymphoid cells to against colorectal tumorigenesis.
Bai X, Fu R, Liu Y, Deng J, Fei Q, Duan Z, Zhu C, Fan D
Journal of pharmaceutical analysis 2024 Feb;14(2):259-275
Journal of pharmaceutical analysis 2024 Feb;14(2):259-275
(-)-Syringaresinol attenuates ulcerative colitis by improving intestinal epithelial barrier function and inhibiting inflammatory responses.
Liu Y, Wu J, Tan L, Li Z, Gao P, He S, Wang Q, Tang D, Wang C, Wang F, Li P, Liu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155292
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155292
Solobacterium moorei promotes the progression of adenomatous polyps by causing inflammation and disrupting the intestinal barrier.
Yu S, Wang X, Li Z, Jin D, Yu M, Li J, Li Y, Liu X, Zhang Q, Liu Y, Liu R, Wang X, Fang B, Zhang C, Wang R, Ren F
Journal of translational medicine 2024 Feb 17;22(1):169
Journal of translational medicine 2024 Feb 17;22(1):169
CAMSAP3, a microtubule orientation regulator, plays a vital role in manifesting differentiation-dependent characteristics in keratinocytes.
Kobori M, Abe J, Saito R, Hirai Y
Experimental cell research 2024 Feb 1;435(1):113927
Experimental cell research 2024 Feb 1;435(1):113927
Therapeutic potential of Lacticaseibacillus rhamnosus grx10 and its derived postbiotic through gut microbiota and MAPK/MLCK/MLC pathway-mediated intestinal barrier repairment in ulcerative colitis.
Ye H, Liu X, Guan K, Ma Y, Liu R, Liu Y, Lv X, Wang R, Li Q
Journal of food science 2024 Dec;89(12):10035-10052
Journal of food science 2024 Dec;89(12):10035-10052
Temporal dynamics of neutrophil functions in multiple sclerosis.
Shen S, Wu S, Wang Y, Xiao L, Sun X, Sun W, Zhao Y, Li R, Zhang J, Wang Z, Zhou S, Huang S, Chang Y, Shu Y, Chen C, Lu Z, Cai W, Qiu W
Neurobiology of disease 2024 Dec;203:106744
Neurobiology of disease 2024 Dec;203:106744
Licorice-regulated gut-joint axis for alleviating collagen-induced rheumatoid arthritis.
Yang D, Lv G, Wu Y, Guo W, Wang Y, Hu J, Li N, Zheng F, Dai Y, Pi Z, Yue H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156203
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156203
Paeoniae radix alba improved intestinal mucosal microcirculation disturbance by regulating lncRNA MALAT1/HIF-1α pathway in the treatment of ulcerative colitis.
Gu Y, Dong Z, Gu Y, Gao Y, Li D, Zhang Y, Zhang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156037
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156037
Silk fibroin microneedles loaded with epigallocatechin gallate mitigate atrazine-induced testicular toxicity.
Fang C, Li Y, He G, Gan RY, Luo F, Lei L, Hou X, Ye Y
Journal of hazardous materials 2024 Dec 5;480:136252
Journal of hazardous materials 2024 Dec 5;480:136252
Xiaoyaosan against depression through suppressing LPS mediated TLR4/NLRP3 signaling pathway in "microbiota-gut-brain" axis.
Liu X, Liu H, Wu X, Zhao Z, Wang S, Wang H, Qin X
Journal of ethnopharmacology 2024 Dec 5;335:118683
Journal of ethnopharmacology 2024 Dec 5;335:118683
Polysaccharides, the active component of Dendrobiumofficinale flower, ameliorates chronic pharyngitis in rats via TLR4/NF-κb pathway regulation.
Yan M, Tian Y, Fu M, Zhou H, Yu J, Su J, Chen Z, Tao Z, Zhu Y, Hu X, Zheng J, Chen S, Chen J, Lv G
Journal of ethnopharmacology 2024 Dec 5;335:118620
Journal of ethnopharmacology 2024 Dec 5;335:118620
Formononetin ameliorates dextran sulfate sodium-induced colitis via enhancing antioxidant capacity, promoting tight junction protein expression and reshaping M1/M2 macrophage polarization balance.
Xiao Q, Huang J, Zhu X, Shi M, Chen L, Chen L, Liu X, Liu R, Zhong Y
International immunopharmacology 2024 Dec 5;142(Pt B):113174
International immunopharmacology 2024 Dec 5;142(Pt B):113174
Efficacy of DHA-enriched phosphatidylserine and its underlying mechanism in alleviating polystyrene nanoplastics-induced hepatotoxicity in mice.
Zhang Y, Zhao Q, Zhao R, Lu Y, Jiang S, Tang Y
International immunopharmacology 2024 Dec 5;142(Pt A):113154
International immunopharmacology 2024 Dec 5;142(Pt A):113154
Fructo-oligosaccharides Alleviated Ulcerative Colitis via Gut Microbiota-Dependent Tryptophan Metabolism in Association with Aromatic Hydrocarbon Receptor Activation in Mice.
Yang C, Du Y, Li Q, Liu L, Zhao L, Gao C, Tang Z, Zhang X, Zhao Y, Yang X
Journal of agricultural and food chemistry 2024 Dec 18;72(50):27912-27922
Journal of agricultural and food chemistry 2024 Dec 18;72(50):27912-27922
Chitosan-alginate/R8 ternary polyelectrolyte complex as an oral protein-based vaccine candidate induce effective mucosal immune responses.
Liu Y, Long M, Wang Y, Liang Z, Dong Y, Qu M, Ge X, Nan Y, Chen Y, Zhou X
International journal of biological macromolecules 2024 Aug;275(Pt 2):133671
International journal of biological macromolecules 2024 Aug;275(Pt 2):133671
Innate lymphoid cell-based immunomodulatory hydrogel microspheres containing Cutibacterium acnes extracellular vesicles for the treatment of psoriasis.
Xu Y, Gan Y, Qi F, Lu X, Zhang X, Zhang J, Wang H, Li Y, Zhou Z, Wang X, Zeng D, Lu F, Zhang C, Cheng B, Hu Z, Wang G
Acta biomaterialia 2024 Aug;184:296-312
Acta biomaterialia 2024 Aug;184:296-312
STC2 suppresses triple-negative breast cancer migration and invasion by inhibition on EMT and promotion on cell apoptosis.
Lei R, Yao C, Huang R, Wu W, Ou L, Yang C
Discover oncology 2024 Aug 9;15(1):339
Discover oncology 2024 Aug 9;15(1):339
Capsaicin combined with cisplatin inhibits TGF-β1-induced EMT and TSCC cells migration via the Claudin-1/PI3K/AKT/mTOR signaling pathway.
Li Z, Zhao Q, Liu X, Zhou X, Wang Y, Zhao M, Wu F, Zhao G, Guo X
Cancer cell international 2024 Aug 28;24(1):300
Cancer cell international 2024 Aug 28;24(1):300
Lactobacillus-derived indole derivatives ameliorate intestinal barrier damage in rat pups with complementary food administration.
Wang A, Guan C, Wang T, Mu G, Tuo Y
Food & function 2024 Aug 27;15(17):8775-8787
Food & function 2024 Aug 27;15(17):8775-8787
Integrated Multi-Omics Analysis Reveals Mountain-Cultivated Ginseng Ameliorates Cold-Stimulated Steroid-Resistant Asthma by Regulating Interactions among Microbiota, Genes, and Metabolites.
Tang D, Wang C, Liu H, Wu J, Tan L, Liu S, Lv H, Wang C, Wang F, Liu J
International journal of molecular sciences 2024 Aug 22;25(16)
International journal of molecular sciences 2024 Aug 22;25(16)
Dietary rutin improves the antidiarrheal capacity of weaned piglets by improving intestinal barrier function, antioxidant capacity and cecal microbiota composition.
Ma L, Zhou B, Liu H, Chen S, Zhang J, Wang T, Wang C
Journal of the science of food and agriculture 2024 Aug 15;104(10):6262-6275
Journal of the science of food and agriculture 2024 Aug 15;104(10):6262-6275
l-Theanine Prevents Colonic Damage via NF-κB/MAPK Signaling Pathways Induced by a High-Fat Diet in Rats.
Fang C, Shen Y, Ma Z, Li Y, Zhang J, Liu C, Ye Y
Molecular nutrition & food research 2024 Apr;68(8):e2300797
Molecular nutrition & food research 2024 Apr;68(8):e2300797
Anionic polysaccharides benefit the bioavailability of pork myofibrillar protein gels: Evidence from a perspective of protein absorption and metabolism.
Yu X, Nie W, Chen X, Zou LF, Xu BC, Chen CG
International journal of biological macromolecules 2024 Apr;263(Pt 1):130246
International journal of biological macromolecules 2024 Apr;263(Pt 1):130246
L-theanine attenuates H(2)O(2)-induced inflammation and apoptosis in IPEC-J2 cells via inhibiting p38 MAPK signaling pathway.
Li Z, Huang Z, Jia G, Zhao H, Liu G, Chen X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114561
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114561
Lactiplantibacillus plantarum-Derived Indole-3-lactic Acid Ameliorates Intestinal Barrier Integrity through the AhR/Nrf2/NF-κB Axis.
Wang A, Guan C, Wang T, Mu G, Tuo Y
Journal of agricultural and food chemistry 2024 Apr 10;
Journal of agricultural and food chemistry 2024 Apr 10;
Coptis chinensis and Berberine Ameliorate Chronic Ulcerative Colitis: An Integrated Microbiome-Metabolomics Study.
Zhou R, Huang Y, Tian C, Yang Y, Zhang Z, He K
The American journal of Chinese medicine 2023;51(8):2195-2220
The American journal of Chinese medicine 2023;51(8):2195-2220
Indole-3-Aldehyde Reduces Inflammatory Responses and Restores Intestinal Epithelial Barrier Function Partially via Aryl Hydrocarbon Receptor (AhR) in Experimental Colitis Models.
Wang M, Guo J, Hart AL, Li JV
Journal of inflammation research 2023;16:5845-5864
Journal of inflammation research 2023;16:5845-5864
Hazara orthonairovirus nucleoprotein facilitates viral cell-to-cell spread by modulating tight junction protein, claudin-1.
Ohta K, Saka N, Fukasawa M, Nishio M
Frontiers in microbiology 2023;14:1192956
Frontiers in microbiology 2023;14:1192956
Wnt4 increases the thickness of the epidermis in burn wounds by activating canonical Wnt signalling and decreasing the cell junctions between epidermal cells.
Xiang F, Wang P, Gong H, Luo J, Zhou X, Zhan C, Hu T, Wang M, Xing Y, Guo H, Luo G, Li Y
Burns & trauma 2023;11:tkac053
Burns & trauma 2023;11:tkac053
Mitigation of maternal fecal microbiota transplantation on neurobehavioral deficits of offspring rats prenatally exposed to arsenic: Role of microbiota-gut-brain axis.
Zhao Q, Hao Y, Yang X, Mao J, Tian F, Gao Y, Tian X, Yan X, Qiu Y
Journal of hazardous materials 2023 Sep 5;457:131816
Journal of hazardous materials 2023 Sep 5;457:131816
DUOX2-Induced Oxidative Stress Inhibits Intestinal Angiogenesis through MMP3 in a Low-Birth-Weight Piglet Model.
Zou D, Yang Y, Ji F, Lv R, Xu T, Hu C
Antioxidants (Basel, Switzerland) 2023 Sep 25;12(10)
Antioxidants (Basel, Switzerland) 2023 Sep 25;12(10)
Resveratrol alleviates DSS-induced IBD in mice by regulating the intestinal microbiota-macrophage-arginine metabolism axis.
Xu X, Ocansey DKW, Pei B, Zhang Y, Wang N, Wang Z, Mao F
European journal of medical research 2023 Sep 2;28(1):319
European journal of medical research 2023 Sep 2;28(1):319
Auricularia auricula polysaccharides attenuate obesity in mice through gut commensal Papillibacter cinnamivorans.
Zong X, Zhang H, Zhu L, Deehan EC, Fu J, Wang Y, Jin M
Journal of advanced research 2023 Oct;52:203-218
Journal of advanced research 2023 Oct;52:203-218
Transcriptional Analysis of lncRNA and Target Genes Induced by Influenza A Virus Infection in MDCK Cells.
Liu G, Pei M, Wang S, Qiu Z, Li X, Ma H, Ma Y, Wang J, Qiao Z, Ma Z, Liu Z
Vaccines 2023 Oct 14;11(10)
Vaccines 2023 Oct 14;11(10)
Role of SIRT2 in intestinal barrier under cold exposure.
Guo J, Xu J, Chen L, Chen Z, Hu H, Nie J, Yuan J, Ma L, Lu J, Ji H, Xu B
Life sciences 2023 Oct 1;330:121949
Life sciences 2023 Oct 1;330:121949
Quercetin Attenuates the Combined Effects of Zearalenone and Lipopolysaccharide on IPEC-J2 Cell Injury through Activating the Nrf2 Signaling Pathway.
Wang C, Fu Y, Wang R, Wang Q, Yu H, Zhang J
Toxins 2023 Nov 30;15(12)
Toxins 2023 Nov 30;15(12)
Green Pea (Pisum sativum L.) Hull Polyphenol Extract Alleviates NAFLD through VB6/TLR4/NF-κB and PPAR Pathways.
Guo F, Xiong H, Tsao R, Shahidi F, Wen X, Liu J, Jiang L, Sun Y
Journal of agricultural and food chemistry 2023 Nov 1;71(43):16067-16078
Journal of agricultural and food chemistry 2023 Nov 1;71(43):16067-16078
Adherent-invasive Escherichia coli LF82 aggravated intestinal inflammation in colitis mice by affecting the gut microbiota and Th17/Treg cell differentiation balance.
Sha S, Zeng H, Gao H, Shi H, Quan X, Chen F, Liu M, Xu B, Liu X
Archives of microbiology 2023 May 5;205(6):218
Archives of microbiology 2023 May 5;205(6):218
The mediation of the AHR/IL-22/STAT3/IL-6 axis by soft-shelled turtle (Pelodiscus sinensis) peptide and Chinese pond turtle (Chinemys reevesii) peptide contributed to their amelioration effects on intestinal mucosal immunity in immunosuppressed mice.
Zhuang J, Wang Q, Shen F, Wang J, Du J, Yu P, Feng F, Zhao M
Food & function 2023 May 22;14(10):4681-4695
Food & function 2023 May 22;14(10):4681-4695
Transcription factor Dmrt1 triggers the SPRY1-NF-κB pathway to maintain testicular immune homeostasis and male fertility.
Zhang MF, Wan SC, Chen WB, Yang DH, Liu WQ, Li BL, Aierken A, Du XM, Li YX, Wu WP, Yang XC, Wei YD, Li N, Peng S, Li XL, Li GP, Hua JL
Zoological research 2023 May 18;44(3):505-521
Zoological research 2023 May 18;44(3):505-521
Polygonum tinctorium leaf extract ameliorates high-fat diet-induced intestinal epithelial damage in mice.
Kawaguchi S, Sakuraba H, Kikuchi H, Matsuki K, Hayashi Y, Ding J, Tanaka Y, Seya K, Matsumiya T, Hiraga H, Fukuda S, Sasaki K, Imaizumi T
Experimental and therapeutic medicine 2023 Mar;25(3):112
Experimental and therapeutic medicine 2023 Mar;25(3):112
Calcitonin gene-related peptide ameliorates sepsis-induced intestinal injury by suppressing NLRP3 inflammasome activation.
Ning W, Gao G, Zhou Y, Li WQ, Yang HH, Duan XB, Li X, Gong YB, Li D, Guo R
International immunopharmacology 2023 Mar;116:109747
International immunopharmacology 2023 Mar;116:109747
IGFBP2 derived from PO-MSCs promote epithelial barrier destruction by activating FAK signaling in nasal polyps.
You B, Zhang T, Zhang W, Pei Y, Huang D, Lei Y, Zhang S, Qiu C, Zhang J, Gu Z, Cheng L, Chen J
iScience 2023 Mar 17;26(3):106151
iScience 2023 Mar 17;26(3):106151
Compatibility between cold-natured medicine CP and hot-natured medicine AZ synergistically mitigates colitis mice through attenuating inflammation and restoring gut barrier.
Li YY, He YX, Wu YQ, Liu C, Ren LZ, Lu XY, Wang YM, Yu Y
Journal of ethnopharmacology 2023 Mar 1;303:115902
Journal of ethnopharmacology 2023 Mar 1;303:115902
Rabeprazole destroyed gastric epithelial barrier function through FOXF1/STAT3-mediated ZO-1 expression.
Yang F, Li L, Zhou Y, Pan W, Liang X, Huang L, Huang J, Cheng Y, Geng L, Xu W, Gong S
Clinical and experimental pharmacology & physiology 2023 Jun;50(6):516-526
Clinical and experimental pharmacology & physiology 2023 Jun;50(6):516-526
Diosmetin Maintains Barrier Integrity by Reducing the Expression of ABCG2 in Colonic Epithelial Cells.
Liu J, Fu L, Yin F, Yin L, Song X, Guo H, Liu J
Journal of agricultural and food chemistry 2023 Jun 14;71(23):8931-8940
Journal of agricultural and food chemistry 2023 Jun 14;71(23):8931-8940
Human umbilical cord mesenchymal stem cells derived exosome shuttling mir-129-5p attenuates inflammatory bowel disease by inhibiting ferroptosis.
Wei Z, Hang S, Wiredu Ocansey DK, Zhang Z, Wang B, Zhang X, Mao F
Journal of nanobiotechnology 2023 Jun 12;21(1):188
Journal of nanobiotechnology 2023 Jun 12;21(1):188
Hederacoside C ameliorates colitis via restoring impaired intestinal barrier through moderating S100A9/MAPK and neutrophil recruitment inactivation.
Zha ZX, Lin Y, Wang KX, Zhang YL, Li D, Xu GQ, Xu QM, Liu YL
Acta pharmacologica Sinica 2023 Jan;44(1):105-119
Acta pharmacologica Sinica 2023 Jan;44(1):105-119
Polysaccharide-rich fractions from Enteromorpha prolifera improve hepatic steatosis and gut barrier integrity in high-fat diet-induced obese mice linking to modulation of gut microbiota.
Zou T, Xie F, Liang P, Chen J, Wang Z, Du M, You J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jan;157:114034
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jan;157:114034
Subacute Ruminal Acidosis as a Potential Factor that Induces Endometrium Injury in Sheep.
Zeng J, Lv J, Duan H, Yang S, Wu J, Yan Z, Zhang R, Hu J, Zhang Y
International journal of molecular sciences 2023 Jan 7;24(2)
International journal of molecular sciences 2023 Jan 7;24(2)
Fecal microbiota transplantation attenuates Escherichia coli infected outgrowth by modulating the intestinal microbiome.
Wang Y, He Y, Liang Y, Liu H, Chen X, Kulyar MF, Shahzad A, Wei K, Li K
Microbial cell factories 2023 Feb 17;22(1):30
Microbial cell factories 2023 Feb 17;22(1):30
Gegen Qinlian decoction activates AhR/IL-22 to repair intestinal barrier by modulating gut microbiota-related tryptophan metabolism in ulcerative colitis mice.
Wang X, Huang S, Zhang M, Su Y, Pan Z, Liang J, Xie X, Wang Q, Chen J, Zhou L, Luo X
Journal of ethnopharmacology 2023 Feb 10;302(Pt B):115919
Journal of ethnopharmacology 2023 Feb 10;302(Pt B):115919
Dietary pectin attenuates Salmonella typhimurium-induced colitis by modulating the TLR2-NF-κB pathway and intestinal microbiota in mice.
Li J, Bai J, Song Z, Ji Y, Chen Z, Yang Y, Wu Z
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Dec;182:114100
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Dec;182:114100
Continuous oral exposure to micro- and nanoplastics induced gut microbiota dysbiosis, intestinal barrier and immune dysfunction in adult mice.
Zhang Z, Xu M, Wang L, Gu W, Li X, Han Z, Fu X, Wang X, Li X, Su Z
Environment international 2023 Dec;182:108353
Environment international 2023 Dec;182:108353
Dual-Targeted Nanoparticle-in-Microparticle System for Ulcerative Colitis Therapy.
Zhang Y, Wu Y, Yan Y, Ma Y, Tu L, Shao J, Tang X, Chen L, Liang G, Yin L
Advanced healthcare materials 2023 Dec;12(31):e2301518
Advanced healthcare materials 2023 Dec;12(31):e2301518
Bioconversion of feather waste into bioactive nutrients in water by Bacillus licheniformis WHU.
Zhang J, Liang M, Wu L, Yang Y, Sun Y, Wang Q, Gao X
Applied microbiology and biotechnology 2023 Dec;107(23):7055-7070
Applied microbiology and biotechnology 2023 Dec;107(23):7055-7070
Potential Toxicity and Mechanisms of T-2 and HT-2 Individually or in Combination on the Intestinal Barrier Function of Porcine Small Intestinal Epithelial Cells.
He W, Wang J, Han M, Wang L, Li L, Zhang J, Chen S, Guo J, Zhai X, Yang J
Toxins 2023 Dec 4;15(12)
Toxins 2023 Dec 4;15(12)
Bacterial butyrate mediates the anti-atherosclerotic effect of silybin.
Shen HR, Wang ZY, Shen Z, Liu TT, Guo YD, Gao TL, Guo HH, Han YX, Jiang JD
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115916
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115916
Succinate signaling attenuates high-fat diet-induced metabolic disturbance and intestinal barrier dysfunction.
Li X, Huang G, Zhang Y, Ren Y, Zhang R, Zhu W, Yu K
Pharmacological research 2023 Aug;194:106865
Pharmacological research 2023 Aug;194:106865
Arula-7 powder improves diarrhea and intestinal epithelial tight junction function associated with its regulation of intestinal flora in calves infected with pathogenic Escherichia coli O(1).
Chen H, Jia Z, He M, Chen A, Zhang X, Xu J, Wang C
Microbiome 2023 Aug 5;11(1):172
Microbiome 2023 Aug 5;11(1):172
Mechanisms of Lung and Intestinal Microbiota and Innate Immune Changes Caused by Pathogenic Enterococcus Faecalis Promoting the Development of Pediatric Pneumonia.
Tian Z, Deng T, Gui X, Wang L, Yan Q, Wang L
Microorganisms 2023 Aug 31;11(9)
Microorganisms 2023 Aug 31;11(9)
PA-MSHA Regulates PD-L1 Expression in Hepatoma Cells.
Wei H, Mao Y, Zhang H, Wu F, Zhang Y
Immunological investigations 2023 Apr;52(3):343-363
Immunological investigations 2023 Apr;52(3):343-363
Astragalus polysaccharides alleviate type 1 diabetes via modulating gut microbiota in mice.
Yang B, Xiong Z, Lin M, Yang Y, Chen Y, Zeng J, Jia X, Feng L
International journal of biological macromolecules 2023 Apr 15;234:123767
International journal of biological macromolecules 2023 Apr 15;234:123767
Subchronic Microcystin-LR Aggravates Colorectal Inflammatory Response and Barrier Disruption via Raf/ERK Signaling Pathway in Obese Mice.
Yang Y, Zheng S, Chu H, Du C, Chen M, Emran MY, Chen J, Yang F, Tian L
Toxins 2023 Apr 1;15(4)
Toxins 2023 Apr 1;15(4)
Morchella esculenta mushroom polysaccharide attenuates diabetes and modulates intestinal permeability and gut microbiota in a type 2 diabetic mice model.
Rehman AU, Siddiqui NZ, Farooqui NA, Alam G, Gul A, Ahmad B, Asim M, Khan AI, Xin Y, Zexu W, Song Ju H, Xin W, Lei S, Wang L
Frontiers in nutrition 2022;9:984695
Frontiers in nutrition 2022;9:984695
The Protective Effect of Sulforaphane on Dextran Sulfate Sodium-Induced Colitis Depends on Gut Microbial and Nrf2-Related Mechanism.
He C, Gao M, Zhang X, Lei P, Yang H, Qing Y, Zhang L
Frontiers in nutrition 2022;9:893344
Frontiers in nutrition 2022;9:893344
Honokiol Ameliorates DSS-Induced Mouse Colitis by Inhibiting Inflammation and Oxidative Stress and Improving the Intestinal Barrier.
Wang L, Wang J
Oxidative medicine and cellular longevity 2022;2022:1755608
Oxidative medicine and cellular longevity 2022;2022:1755608
Knockout of IL-6 mitigates cold water-immersion restraint stress-induced intestinal epithelial injury and apoptosis.
Zhang Y, Duan C, Wu S, Ma J, Liu Y, Li W, Wang T, Yang L, Cheng K, Zhuang R
Frontiers in immunology 2022;13:936689
Frontiers in immunology 2022;13:936689
Cassane diterpenoid ameliorates dextran sulfate sodium-induced experimental colitis by regulating gut microbiota and suppressing tryptophan metabolism.
Liu T, Ning Z, Liu P, Gao H
Frontiers in immunology 2022;13:1045901
Frontiers in immunology 2022;13:1045901
Comprehensive analysis of cuproptosis-related genes in immune infiltration and diagnosis in ulcerative colitis.
Huang J, Zhang J, Wang F, Zhang B, Tang X
Frontiers in immunology 2022;13:1008146
Frontiers in immunology 2022;13:1008146
Morchella esculenta polysaccharide attenuate obesity, inflammation and modulate gut microbiota.
Rehman AU, Khan AI, Xin Y, Liang W
AMB Express 2022 Sep 3;12(1):114
AMB Express 2022 Sep 3;12(1):114
The Barrier-Enhancing Function of Soluble Yam (Dioscorea opposita Thunb.) Polysaccharides in Rat Intestinal Epithelial Cells as Affected by the Covalent Se Conjugation.
Wang ZX, Zhao XH
Nutrients 2022 Sep 23;14(19)
Nutrients 2022 Sep 23;14(19)
Yajieshaba prevents lipopolysaccharide-induced intestinal barrier injuryanti-inflammatory and anti-apoptosis.
Liping Y, Xinglin YU, Chao Z, Pu C, Xiaohua D
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Oct;42(5):707-714
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Oct;42(5):707-714
Bisdemethoxycurcumin Alleviates Dextran Sodium Sulfate-Induced Colitis via Inhibiting NLRP3 Inflammasome Activation and Modulating the Gut Microbiota in Mice.
Zhang J, Li Q, Zhang X, Chen Y, Lu Y, Wang X, Zhang L, Wang T
Antioxidants (Basel, Switzerland) 2022 Oct 7;11(10)
Antioxidants (Basel, Switzerland) 2022 Oct 7;11(10)
The beneficial effects of Polygonatum sibiricum Red. superfine powder on metabolic hypertensive rats via gut-derived LPS/TLR4 pathway inhibition.
Su J, Wang Y, Yan M, He Z, Zhou Y, Xu J, Li B, Xu W, Yu J, Chen S, Lv G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Nov;106:154404
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Nov;106:154404
Strains producing different short-chain fatty acids alleviate DSS-induced ulcerative colitis by regulating intestinal microecology.
Yang S, Shang J, Liu L, Tang Z, Meng X
Food & function 2022 Nov 28;13(23):12156-12169
Food & function 2022 Nov 28;13(23):12156-12169
Apple Polyphenols Improve Intestinal Antioxidant Capacity and Barrier Function by Activating the Nrf2/Keap1 Signaling Pathway in a Pig Model.
Huang T, Che Q, Chen X, Chen D, Yu B, He J, Chen H, Yan H, Zheng P, Luo Y, Huang Z
Journal of agricultural and food chemistry 2022 Jun 22;70(24):7576-7585
Journal of agricultural and food chemistry 2022 Jun 22;70(24):7576-7585
Ameloblastin promotes polarization of ameloblast cell lines in a 3-D cell culture system.
Visakan G, Su J, Moradian-Oldak J
Matrix biology : journal of the International Society for Matrix Biology 2022 Jan;105:72-86
Matrix biology : journal of the International Society for Matrix Biology 2022 Jan;105:72-86
The effect of Porphyromonas gingivalis on the gut microbiome of mice in relation to aging.
Giri S, Uehara O, Takada A, Paudel D, Morikawa T, Arakawa T, Nagasawa T, Abiko Y, Furuichi Y
Journal of periodontal research 2022 Dec;57(6):1256-1266
Journal of periodontal research 2022 Dec;57(6):1256-1266
Effects of betaine on viability, apoptosis, function protein expression and oxidative status in heat-stressed IEC-6 cells.
Sun S, Yin Q, Li B, Deng Y, Li J, Xiong Y, Shaojun H
Journal of thermal biology 2022 Dec;110:103348
Journal of thermal biology 2022 Dec;110:103348
Glutathione Protects against Paraquat-Induced Oxidative Stress by Regulating Intestinal Barrier, Antioxidant Capacity, and CAR Signaling Pathway in Weaned Piglets.
Xiang X, Wang H, Zhou W, Wang C, Guan P, Xu G, Zhao Q, He L, Yin Y, Li T
Nutrients 2022 Dec 30;15(1)
Nutrients 2022 Dec 30;15(1)
Aerobic exercise improves intestinal mucosal barrier dysfunction through TLR4/MyD88/NF-κB signaling pathway in diabetic rats.
Li J, Liu X, Wu Y, Ji W, Tian Q, Li S
Biochemical and biophysical research communications 2022 Dec 17;634:75-82
Biochemical and biophysical research communications 2022 Dec 17;634:75-82
Fucoidan ameliorates LPS-induced neuronal cell damage and cognitive impairment in mice.
Wang Y, Wang Q, Duan L, Li X, Yang W, Huang T, Kong M, Guan F, Ma S
International journal of biological macromolecules 2022 Dec 1;222(Pt A):759-771
International journal of biological macromolecules 2022 Dec 1;222(Pt A):759-771
Oxycodone protects cardiac microvascular endothelial cells against ischemia/reperfusion injury by binding to Sigma-1 Receptor.
Ji M, Cheng J, Zhang D
Bioengineered 2022 Apr;13(4):9628-9644
Bioengineered 2022 Apr;13(4):9628-9644
Postconditioning of stellate ganglion block improves intestinal barrier function by inhibiting autophagy in conscious rats following hemorrhagic shock and resuscitation.
Li Z, Wang W, Sun Q, Suo T, Zhai J, Du H, Zhao Z, Li F, Niu C, Zhao Z
Chinese medical journal 2022 Apr 20;135(8):1003-1005
Chinese medical journal 2022 Apr 20;135(8):1003-1005
The effects of PIKfyve inhibitor YM201636 on claudins and malignancy potential of nonsmall cell cancer cells.
DoĞan E, DÜzgÜn Z, Yildirim Z, Özdİl B, AktuĞ H, Bozok ÇetİntaŞ V
Turkish journal of biology = Turk biyoloji dergisi 2021;45(1):26-34
Turkish journal of biology = Turk biyoloji dergisi 2021;45(1):26-34
Gut Microbiota Was Involved in the Process of Liver Injury During Intra-Abdominal Hypertension.
Zhao Z, Guo Z, Yin Z, Qiu Y, Zhou B
Frontiers in physiology 2021;12:790182
Frontiers in physiology 2021;12:790182
Inhibitor of Differentiation-2 Protein Ameliorates DSS-Induced Ulcerative Colitis by Inhibiting NF-κB Activation in Neutrophils.
Ren J, Yan D, Wang Y, Zhang J, Li M, Xiong W, Jing X, Li P, Zhao W, Xiong X, Wu M, Zhong G
Frontiers in immunology 2021;12:760999
Frontiers in immunology 2021;12:760999
Gastrodia remodels intestinal microflora to suppress inflammation in mice with early atherosclerosis.
Liu FY, Wen J, Hou J, Zhang SQ, Sun CB, Zhou LC, Yin W, Pang WL, Wang C, Ying Y, Han SS, Yan JY, Li CX, Yuan JL, Xing HJ, Yang ZS
International immunopharmacology 2021 Jul;96:107758
International immunopharmacology 2021 Jul;96:107758
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