Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB18276 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB18276, RRID:AB_10716926
- Product name
- GAB1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of GAB1.
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references The scaffolding adapter Gab1 mediates vascular endothelial growth factor signaling and is required for endothelial cell migration and capillary formation.
Gab1 contributes to cytoskeletal reorganization and chemotaxis in response to platelet-derived growth factor.
Distinct recruitment and function of Gab1 and Gab2 in Met receptor-mediated epithelial morphogenesis.
Laramée M, Chabot C, Cloutier M, Stenne R, Holgado-Madruga M, Wong AJ, Royal I
The Journal of biological chemistry 2007 Mar 16;282(11):7758-69
The Journal of biological chemistry 2007 Mar 16;282(11):7758-69
Gab1 contributes to cytoskeletal reorganization and chemotaxis in response to platelet-derived growth factor.
Kallin A, Demoulin JB, Nishida K, Hirano T, Rönnstrand L, Heldin CH
The Journal of biological chemistry 2004 Apr 23;279(17):17897-904
The Journal of biological chemistry 2004 Apr 23;279(17):17897-904
Distinct recruitment and function of Gab1 and Gab2 in Met receptor-mediated epithelial morphogenesis.
Lock LS, Maroun CR, Naujokas MA, Park M
Molecular biology of the cell 2002 Jun;13(6):2132-46
Molecular biology of the cell 2002 Jun;13(6):2132-46
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of extracts from NIH/3T3 cells, using GAB1 polyclonal antibody (Cat # PAB18276).Peptide "+" means "peptide blocking".
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunofluorescence analysis of HepG2 cells, using GAB1 polyclonal antibody (Cat # PAB18276).Peptide "+" means "peptide blocking".
- Validation comment
- Immunofluorescence
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using GAB1 polyclonal antibody (Cat # PAB18276).Peptide "+" means "peptide blocking".
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)