Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 16195-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16195-1-AP, RRID:AB_2082969
- Product name
- Claudin 4-specific antibody
- Antibody type
- Polyclonal
- Description
- Claudin 4-specific antibody (Cat. #16195-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Protective Effect of Xiao-Xu-Ming Decoction-Mediated Inhibition of ROS/NLRP3 Axis on Lipopolysaccharide-Induced Acute Lung Injury In Vitro and In Vivo.
Matrine treatment induced an A2 astrocyte phenotype and protected the blood-brain barrier in CNS autoimmunity.
Targeting PVT1 Exon 9 Re-Expresses Claudin 4 Protein and Inhibits Migration by Claudin-Low Triple Negative Breast Cancer Cells.
Expression of Grainyhead-like 2 in the Process of Ductal Development of Mouse Mammary Gland.
Long noncoding RNA AFAP1-AS1 promotes tumor progression and invasion by regulating the miR-2110/Sp1 axis in triple-negative breast cancer.
Prenylated xanthones from mangosteen (Garcinia mangostana) activate the AhR and Nrf2 pathways and protect intestinal barrier integrity in HT-29 cells.
A proteomic atlas of ligand-receptor interactions at the ovine maternal-fetal interface reveals the role of histone lactylation in uterine remodeling.
Kaempferol attenuates diquat-induced oxidative damage and apoptosis in intestinal porcine epithelial cells.
ROS Plays a Role in the Neonatal Rat Intestinal Barrier Damages Induced by Hyperoxia.
Dual effects of JNK activation in blood-milk barrier damage induced by zinc oxide nanoparticles.
Targeting claudin-4 enhances chemosensitivity in breast cancer.
Effects of applying amoxicillin in juvenile mice on enamel mineralization and the expression of kallikrein‑related peptidase 4 and tight junction proteins in ameloblasts.
Persistence of a regeneration-associated, transitional alveolar epithelial cell state in pulmonary fibrosis.
The chromatin remodeling protein BRM regulates the transcription of tight junction proteins: Implication in breast cancer metastasis.
Endotoxemia alters tight junction gene and protein expression in the kidney.
Xiang Y, Cai M, Li X, Bao X, Cai D
Evidence-based complementary and alternative medicine : eCAM 2021;2021:8257495
Evidence-based complementary and alternative medicine : eCAM 2021;2021:8257495
Matrine treatment induced an A2 astrocyte phenotype and protected the blood-brain barrier in CNS autoimmunity.
Jing Y, Ma R, Chu Y, Dou M, Wang M, Li X, Zhu L
Journal of chemical neuroanatomy 2021 Nov;117:102004
Journal of chemical neuroanatomy 2021 Nov;117:102004
Targeting PVT1 Exon 9 Re-Expresses Claudin 4 Protein and Inhibits Migration by Claudin-Low Triple Negative Breast Cancer Cells.
Levine F, Ogunwobi OO
Cancers 2021 Mar 2;13(5)
Cancers 2021 Mar 2;13(5)
Expression of Grainyhead-like 2 in the Process of Ductal Development of Mouse Mammary Gland.
Matsuoka S, Suzuki H, Kato C, Kamikawa-Tokai M, Kamikawa A, Okamatsu-Ogura Y, Kimura K
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2021 Jun;69(6):373-388
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2021 Jun;69(6):373-388
Long noncoding RNA AFAP1-AS1 promotes tumor progression and invasion by regulating the miR-2110/Sp1 axis in triple-negative breast cancer.
Zhang X, Li F, Zhou Y, Mao F, Lin Y, Shen S, Li Y, Zhang S, Sun Q
Cell death & disease 2021 Jun 18;12(7):627
Cell death & disease 2021 Jun 18;12(7):627
Prenylated xanthones from mangosteen (Garcinia mangostana) activate the AhR and Nrf2 pathways and protect intestinal barrier integrity in HT-29 cells.
Tocmo R, Le B, Heun A, van Pijkeren JP, Parkin K, Johnson JJ
Free radical biology & medicine 2021 Feb 1;163:102-115
Free radical biology & medicine 2021 Feb 1;163:102-115
A proteomic atlas of ligand-receptor interactions at the ovine maternal-fetal interface reveals the role of histone lactylation in uterine remodeling.
Yang Q, Liu J, Wang Y, Zhao W, Wang W, Cui J, Yang J, Yue Y, Zhang S, Chu M, Lyu Q, Ma L, Tang Y, Hu Y, Miao K, Zhao H, Tian J, An L
The Journal of biological chemistry 2021 Dec 1;298(1):101456
The Journal of biological chemistry 2021 Dec 1;298(1):101456
Kaempferol attenuates diquat-induced oxidative damage and apoptosis in intestinal porcine epithelial cells.
Jin Y, Zhai Z, Jia H, Lai J, Si X, Wu Z
Food & function 2021 Aug 2;12(15):6889-6899
Food & function 2021 Aug 2;12(15):6889-6899
ROS Plays a Role in the Neonatal Rat Intestinal Barrier Damages Induced by Hyperoxia.
Liu DY, Lou WJ, Zhang DY, Sun SY
BioMed research international 2020;2020:8819195
BioMed research international 2020;2020:8819195
Dual effects of JNK activation in blood-milk barrier damage induced by zinc oxide nanoparticles.
Wu J, Lai X, Cui G, Chen Q, Liu J, Kang Y, Zhang Y, Feng X, Hu C, Shao L
Journal of hazardous materials 2020 Nov 15;399:122809
Journal of hazardous materials 2020 Nov 15;399:122809
Targeting claudin-4 enhances chemosensitivity in breast cancer.
Luo Y, Kishi S, Sasaki T, Ohmori H, Fujiwara-Tani R, Mori S, Goto K, Nishiguchi Y, Mori T, Kawahara I, Kondoh M, Kuniyasu H
Cancer science 2020 May;111(5):1840-1850
Cancer science 2020 May;111(5):1840-1850
Effects of applying amoxicillin in juvenile mice on enamel mineralization and the expression of kallikrein‑related peptidase 4 and tight junction proteins in ameloblasts.
Gao J, Li X, Gao L, Chen H, Baras BH, Liu X, Liu H, Rana A, Gao M, Ruan J
International journal of molecular medicine 2020 Jul;46(1):179-190
International journal of molecular medicine 2020 Jul;46(1):179-190
Persistence of a regeneration-associated, transitional alveolar epithelial cell state in pulmonary fibrosis.
Kobayashi Y, Tata A, Konkimalla A, Katsura H, Lee RF, Ou J, Banovich NE, Kropski JA, Tata PR
Nature cell biology 2020 Aug;22(8):934-946
Nature cell biology 2020 Aug;22(8):934-946
The chromatin remodeling protein BRM regulates the transcription of tight junction proteins: Implication in breast cancer metastasis.
Yang Y, Liu L, Fang M, Bai H, Xu Y
Biochimica et biophysica acta. Gene regulatory mechanisms 2019 May;1862(5):547-556
Biochimica et biophysica acta. Gene regulatory mechanisms 2019 May;1862(5):547-556
Endotoxemia alters tight junction gene and protein expression in the kidney.
Eadon MT, Hack BK, Xu C, Ko B, Toback FG, Cunningham PN
American journal of physiology. Renal physiology 2012 Sep 15;303(6):F821-30
American journal of physiology. Renal physiology 2012 Sep 15;303(6):F821-30
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse small intestine tissue were subjected to SDS PAGE followed by western blot with 16195-1-AP(CLDN4-specific antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Claudin 4-specific antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human Claudin 4-specific. This antibody recognizes human,mouse,rat antigen. The Claudin 4-specific antibody has been validated for the following applications: ELISA, WB, IHC analysis.