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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Immunohistochemistry [1]
- Other assay [1]
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- Product number
- PA5-16875 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Claudin 4 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- PA5-16875 targets Claudin 4 in IHC (P) applications and shows reactivity with Human and mouse samples.
- Concentration
- 2 mg/mL
Submitted references Alpha-Melanocyte Stimulating Hormone Protects against Cytokine-Induced Barrier Damage in Caco-2 Intestinal Epithelial Monolayers.
Profile of skin barrier proteins (filaggrin, claudins 1 and 4) and Th1/Th2/Th17 cytokines in adults with atopic dermatitis.
Detection of claudin-4 in salivary gland neoplasms (a study utilizing RT-PCR and immunohistochemistry).
Váradi J, Harazin A, Fenyvesi F, Réti-Nagy K, Gogolák P, Vámosi G, Bácskay I, Fehér P, Ujhelyi Z, Vasvári G, Róka E, Haines D, Deli MA, Vecsernyés M
PloS one 2017;12(1):e0170537
PloS one 2017;12(1):e0170537
Profile of skin barrier proteins (filaggrin, claudins 1 and 4) and Th1/Th2/Th17 cytokines in adults with atopic dermatitis.
Batista DI, Perez L, Orfali RL, Zaniboni MC, Samorano LP, Pereira NV, Sotto MN, Ishizaki AS, Oliveira LM, Sato MN, Aoki V
Journal of the European Academy of Dermatology and Venereology : JEADV 2015 Jun;29(6):1091-5
Journal of the European Academy of Dermatology and Venereology : JEADV 2015 Jun;29(6):1091-5
Detection of claudin-4 in salivary gland neoplasms (a study utilizing RT-PCR and immunohistochemistry).
Abd El-Ghani SF, Kasem RF, Ghallab NA, Shaker OG
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2013 Nov;42(10):781-7
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2013 Nov;42(10):781-7
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Formalin-fixed, paraffin-embedded human ovarian ca stained with Claudin 4 antibody using peroxidase-conjugate and AEC. Note membrane staining of tumor cells
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Fig 4 The effect of alpha-MSH treatment on the immunostaining of tight juntion proteins claudin-4 and ZO-1 in cytokine treated Caco-2 cells. Caco-2 cells were treated with cytokines (CK; 50 ng/ml TNF-alpha and 25 ng/ml IL-1beta) without or with 10 -8 M alpha-MSH (CK+MSH) for 24 hours, then immunostained for integral membrane tight junction protein claudin-4 and cytoplasmic linker protein ZO-1. The control group (C) received culture medium. The fluorescent microscopy images demonstrate the expression and organization of the junctional proteins. Scale bar: 10 mum.
