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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB1861 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB1861, RRID:AB_1571710
- Product name
- BCL2L11 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of BCL2L11.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Caspase cleavage of BimEL triggers a positive feedback amplification of apoptotic signaling.
Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function.
FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines.
Chen D, Zhou Q
Proceedings of the National Academy of Sciences of the United States of America 2004 Feb 3;101(5):1235-40
Proceedings of the National Academy of Sciences of the United States of America 2004 Feb 3;101(5):1235-40
Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function.
Luciano F, Jacquel A, Colosetti P, Herrant M, Cagnol S, Pages G, Auberger P
Oncogene 2003 Oct 2;22(43):6785-93
Oncogene 2003 Oct 2;22(43):6785-93
FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines.
Sunters A, Fernández de Mattos S, Stahl M, Brosens JJ, Zoumpoulidou G, Saunders CA, Coffer PJ, Medema RH, Coombes RC, Lam EW
The Journal of biological chemistry 2003 Dec 12;278(50):49795-805
The Journal of biological chemistry 2003 Dec 12;278(50):49795-805
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- The BCL2L11 polyclonal antibody (Cat # PAB1861) is used in Western blot to detect BCL2L11 in HL-60 cell lysate.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with BCL2L11 polyclonal antibody (Cat # PAB1861), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
