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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations [0]
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- Product number
- ABIN965669 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) antibody
- Antibody type
- Polyclonal
- Antigen
- The antiserum was produced against synthesized non-phosphopeptide derived from mouse BIM around the phosphorylation site of serine 69 (P-A-SP-P-G).
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 100 μg
- Concentration
- 100ug/100ul.
- Storage
- -20°C
Submitted references BimEL is an important determinant for induction of anoikis sensitivity by mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitors.
Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function.
Fukazawa H, Noguchi K, Masumi A, Murakami Y, Uehara Y
Molecular cancer therapeutics 2004 Oct;3(10):1281-8
Molecular cancer therapeutics 2004 Oct;3(10):1281-8
Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function.
Luciano F, Jacquel A, Colosetti P, Herrant M, Cagnol S, Pages G, Auberger P
Oncogene 2003 Oct 2;22(43):6785-93
Oncogene 2003 Oct 2;22(43):6785-93
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