AGTO-G048A

antibody from Creative Biolabs

Targeting: MAGEA1 CT1.1, MAGE1, MGC9326

Functional assay (Recommended by provider)

Antibody Data

Product number

AGTO-G048A

Provider

Creative Biolabs

Product name

Anti-MAGEA1 immunotoxin (scFv)-ABR

Antibody type

Monoclonal

Description

This immunotoxin was achieved by conjugating/fusing the Anti-MAGEA1 scFv to Abrin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to tumor cells. Once bind, the abrin is subsequently engulfed and enters the inner parts of the cell where it reacts with a ribosomal subunit. It interferes with the normal protein synthesis process of the cell and then inhibits cell protein synthesis. It was designed for treatment of hepatocellular carcinoma.

Reactivity

Human

Host

Mouse