orb385726

antibody from Biorbyt

Targeting: MAGEA1 CT1.1, MAGE1, MGC9326

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

orb385726

Provider

Biorbyt

Product name

MAGE-1 Antibody

Antibody type

Monoclonal

Description

Recognizes a protein of 42-46kDa, identified as MAGE-1. This mAb does not cross-react with MAGE-2, -3, -4, -6 -9, -10, or -12 protein. Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). The MAGE family of genes codes an important group of antigens. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.

Reactivity

Human, Rat

Host

Mouse

Conjugate

Unconjugated

Antibody clone number

MA454

Vial size

20 ug

Storage

Store the MAGE-1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).