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- Antibody Data
- Antigen structure
- References [8]
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- Validations
- Western blot [1]
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- Product number
- 4970 - Provider product page
- Provider
- Cell Signaling Technology, Inc
- Proper citation
- Cell Signaling Technology Cat#4970, RRID:AB_2223172
- Product name
- β-Actin (13E5) Rabbit mAb
- Antibody type
- Monoclonal
- Reactivity
- Human, Mouse, Rat, Bovine, Porcine, Simian
- Host
- Rabbit
- Storage
- -20°C
Submitted references MiR-100 regulates cell differentiation and survival by targeting RBSP3, a phosphatase-like tumor suppressor in acute myeloid leukemia.
The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization.
Heightened induction of proapoptotic signals in response to endoplasmic reticulum stress in primary fibroblasts from a mouse model of longevity.
TWEAK induces apoptosis through a death-signaling complex comprising receptor-interacting protein 1 (RIP1), Fas-associated death domain (FADD), and caspase-8.
Cdk2 and Cdk4 regulate the centrosome cycle and are critical mediators of centrosome amplification in p53-null cells.
Angiotensin II upregulates hypothalamic AT1 receptor expression in rats via the mitogen-activated protein kinase pathway.
TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition.
RhoA regulates G1-S progression of gastric cancer cells by modulation of multiple INK4 family tumor suppressors.
Zheng YS, Zhang H, Zhang XJ, Feng DD, Luo XQ, Zeng CW, Lin KY, Zhou H, Qu LH, Zhang P, Chen YQ
Oncogene 2012 Jan 5;31(1):80-92
Oncogene 2012 Jan 5;31(1):80-92
The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization.
Ippagunta SK, Malireddi RK, Shaw PJ, Neale GA, Vande Walle L, Green DR, Fukui Y, Lamkanfi M, Kanneganti TD
Nature immunology 2011 Sep 4;12(10):1010-6
Nature immunology 2011 Sep 4;12(10):1010-6
Heightened induction of proapoptotic signals in response to endoplasmic reticulum stress in primary fibroblasts from a mouse model of longevity.
Sadighi Akha AA, Harper JM, Salmon AB, Schroeder BA, Tyra HM, Rutkowski DT, Miller RA
The Journal of biological chemistry 2011 Sep 2;286(35):30344-51
The Journal of biological chemistry 2011 Sep 2;286(35):30344-51
TWEAK induces apoptosis through a death-signaling complex comprising receptor-interacting protein 1 (RIP1), Fas-associated death domain (FADD), and caspase-8.
Ikner A, Ashkenazi A
The Journal of biological chemistry 2011 Jun 17;286(24):21546-54
The Journal of biological chemistry 2011 Jun 17;286(24):21546-54
Cdk2 and Cdk4 regulate the centrosome cycle and are critical mediators of centrosome amplification in p53-null cells.
Adon AM, Zeng X, Harrison MK, Sannem S, Kiyokawa H, Kaldis P, Saavedra HI
Molecular and cellular biology 2010 Feb;30(3):694-710
Molecular and cellular biology 2010 Feb;30(3):694-710
Angiotensin II upregulates hypothalamic AT1 receptor expression in rats via the mitogen-activated protein kinase pathway.
Wei SG, Yu Y, Zhang ZH, Felder RB
American journal of physiology. Heart and circulatory physiology 2009 May;296(5):H1425-33
American journal of physiology. Heart and circulatory physiology 2009 May;296(5):H1425-33
TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition.
Zhang H, Liu CY, Zha ZY, Zhao B, Yao J, Zhao S, Xiong Y, Lei QY, Guan KL
The Journal of biological chemistry 2009 May 15;284(20):13355-62
The Journal of biological chemistry 2009 May 15;284(20):13355-62
RhoA regulates G1-S progression of gastric cancer cells by modulation of multiple INK4 family tumor suppressors.
Zhang S, Tang Q, Xu F, Xue Y, Zhen Z, Deng Y, Liu M, Chen J, Liu S, Qiu M, Liao Z, Li Z, Luo D, Shi F, Zheng Y, Bi F
Molecular cancer research : MCR 2009 Apr;7(4):570-80
Molecular cancer research : MCR 2009 Apr;7(4):570-80
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Supportive validation
- Submitted by
- kwokscm
- Main image
- Experimental details
- Top: Blot was incubated with beta-actin (13E5) rabbit mAb (Cell Signaling, #4970) and HO-1 (P249) antibody (Cell Signaling, #5061). Bottom: Same blot was reprobed (without stripping) with HO-1 (Hsp32) polyclonal antibody (Enzo #SPA-894) Dilution for all antibodies is 1:1000
- Sample type
- MCF-7 and PC-3 human cancer cell lines, untreated and atorvastatin-treated
- Primary Ab dilution
- 1:1000
