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- Product number
- 20536-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20536-1-AP, RRID:AB_10700003
- Product name
- beta actin antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Beta Actin antibody (Cat. #20536-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, monkey, canine and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Canine, Simian
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 150ul
Submitted references Hypoxic Reprogramming of ACOX1-Driven HSP90AB1 Crotonylation Stabilizes Thioredoxin to Orchestrate Redox Homeostasis in Oral Squamous Cell Carcinoma.
RBM15 Enhances 5-Fluorouracil Drug Sensitivity and Suppresses Gastric Cancer Progression by Modulating N6-Methyladenosine Modification of ECT2-Dependent IGF2BP3.
A Novel Autophagy Inhibitor p-Hydroxylcinnamaldehyde Suppresses Esophageal Squamous Cell Carcinoma by Targeting LDHA Phosphorylation-Mediated Metabolic Reprogramming.
Response surface methodology optimization extraction of polysaccharide from Lilium brownii F.E. Brown var. viridulum Baker/Longya Baihe and its biological activities.
A novel Nilotinib derivative N-12 inhibits the proliferation and migration of colon cancer cells through the EMT signaling pathway.
Triptonide-mediated PTGS2 Inhibition Induces Autophagic Cell Death to Suppress the Progression of Triple-negative Breast Cancer and Epithelial Ovarian Cancer.
NAT10 Promotes Tubular Epithelial Cell Senescence in Cisplatin-Induced Acute Kidney Injury by Regulating DDX17.
Targeting the LHX1-LDB1 Complex Restores STING-dependent Senescence Surveillance and Inhibits Head and Neck Cancer Progression.
DJ-1 alleviates high glucose-induced podocyte injury via activating ERK1/2 signaling.
A novel SLC20A2 nonsense variant and mechanistic studies of primary brain calcification.
Knockdown of miR-21-5P targets and regulates PDCD4-induced apoptosis in ovarian granulosa cells and ameliorates in sulin resistance in polycystic ovary syndrom.
Spatholobus suberectus Stem-Derived Extracellular Vesicle-Like Particles Attenuate Glucocorticoid-Induced Osteoporosis via NRF2/HO-1 Signaling.
Hsa_circ_0000313/miR-1224-3p/MKNK2 Axis Modulates CD4(+) T Cells by Activating p38 MAPK Signaling in Myasthenia Gravis.
Dexrazoxane Protects Against Hand-Foot Syndrome-Like Skin Damage in Pegylated Liposomal Doxorubicin-Treated Mice.
Cordycepin Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice by Inhibiting IL-6/IL-6R-Mediated p38 MAPK and NF-κB Activation Through Adenosine A(2A) Receptor Stimulation.
Lactoferrin inhibits anoikis-resistance and metastasis of nasopharyngeal carcinoma cells via the AKT signaling pathway.
Integrating Single-Cell and Microarray Data to Explore the Role of Autophagy-Related Gene Atg7 in Osteoporosis.
FGF7-FGFR2 Signaling Enhances Contractile Activation of CAFs in Ovarian Cancer: Integrative Single-Cell and Spatial Transcriptomics.
Gan-Pi-Tong-Zhi Decoction Ameliorates OVA-Induced Asthma Through MAPK and Nrf2 Signaling Pathways and Regulating Gut Microbiota.
Targeting NLRP3 Inflammasome and Metabolic Dysregulation by Electroacupuncture: A Novel Therapeutic Strategy for Methamphetamine Withdrawal-Induced Depression.
The mechanism of Vicenin-2 in ameliorating skin photoaging: involvement of m6A-modified macrophage polarization.
Integrated multi-omics mapping of the causal landscape of gout across the circulating-tissue axis.
Electroacupuncture may improve endometrial receptivity in controlled ovarian hyperstimulation mice by activating AVP neurons.
Licoisoflavone B alleviates psoriasis via SCD1-targeted lipid metabolism reprogramming and suppression of Th17/IL-17-mediated inflammation.
Akkermansia muciniphila alleviates antibiotic- and LPS-induced oxidative stress via the p38α MAPK-Nrf2 signaling axis.
Ebselen, a promising host-directed therapeutic option against Yersinia pseudotuberculosis infection.
M2 macrophage-derived exosomes mitigate acute inflammation following ischemic stroke.
Novel prognostic signature unveils PSEN1 contributes to depression-induced lung adenocarcinoma progression.
CD146(+) pericyte-like lung cancer brain metastatic stem cells promote tumor angiogenesis through dual regulatory effects on the VEGF/VEGFR axis.
The D826V point mutation in IREB2 induces lipogenesis in adipose tissues.
SNX1 inhibits human ovarian cancer progression via regulation of the cell cycle, apoptosis and migration.
ESRP1 drives epithelial-mesenchymal transition by activating EPAC-RAP1A signaling axis.
The NLRP3 inhibitor, MCC950, attenuates environmental pollutant PM(2.5)-induced acute lung injury by inhibiting alveolar macrophage pyroptosis.
Elevated lactate production exacerbates PM2.5-induced pulmonary fibrosis by stabilizing TGF-β1.
Neural stem cell transplantation attenuates cognitive decline and neuroinflammation in a mouse model of Alzheimer's disease with chronic cerebral hypoperfusion.
β-Sitosterol Suppresses Osteoclastogenesis and Alleviates Bone Loss by Targeting Tmed10 to Inhibit RANKL-Induced Hedgehog/MAPK Signaling and ROS.
Dehydrocorydaline Promotes STAT3/Bcl-2 Axis-Mediated Macrophage Efferocytosis to Attenuate Apoptosis in Atherosclerotic Plaques.
Influence of Adipose Mesenchymal Stem Cell-Derived Exosomes on the Th2/Treg Cells in Peripheral Blood of the Patients with Allergic Rhinitis and its Mechanism.
Yeast β-glucan alleviates alcohol-related brain injury by restoring gut-brain axis homeostasis.
Integrated machine learning and experimental validation reveal S6K2 as a key target of 6PPD-quinone in bladder cancer.
Peroxiredoxin 4 suppresses ferroptosis in esophageal squamous cell carcinoma by activating the phosphoinositide 3-kinase signaling pathway.
CYR61 promotes obesity-induced kidney injury by activating endoplasmic reticulum stress.
Sihe Tufuling formula alleviates imiquimod-induced psoriasis-like skin lesions in mice by modulating the HIF-1 signaling pathway.
Ubiquitin-Specific Protease 45 Inhibits Lung Adenocarcinoma Ferroptosis by Regulating Ubiquitination and Stability of Glutathione Peroxidase 4.
Decoding the spatiotemporal development of the blood-brain barrier in human cortex.
Emerging roles for SNRPB2 in governing the cell cycle and steering tumor immune modulation in breast cancer.
Swine GBP1 restricts PDCoV replication via disrupting the replication and transcription complex formation.
Cytoskeletal protein integrity and its relationship with texture formation and rehydration property of dried fish: biochemical and microstructural evidence.
Unleashing T cell surveillance for the eradication of quiescent persister tumor cells resistant to neoadjuvant chemotherapy.
Proteome Profiling Reveals Inflammation and Fibrosis Biomarkers in Urinary Migrasomes of Patients with Diabetic Kidney Disease.
Iron overload reprogramming lipid metabolism through the IRP1-SCAP axis in fibroblast-like synoviocytes aggravates bone destruction in rheumatoid arthritis.
Prenylterphenyllin, a regulator of P53, inhibits colorectal cancer progression through oxidative stress and energy metabolism pathway.
S100B induces angiogenesis via the clathrin/FOXO1/β-catenin signaling pathway and contributes to Bevacizumab resistance in epithelial ovarian cancer.
Voxtalisib inhibits enterovirus 71 replication by downregulating host RAN and restoring IFN-STAT signaling.
Targeted knockdown of Piezo1 in synovial macrophages attenuates osteoarthritis development.
The role of nGPx4 in resisting DEHP-induced DNA damage and reducing caspase-independent cell death in male germ cells.
ANXA1 overexpression promotes B cell acute lymphoblastic leukemia progression and resistance by regulating fatty acid metabolism through PI3K/Akt signaling.
Nobiletin and polydatin synergistically alleviate triple-negative breast cancer liver metastasis via suppressing ECM1a-mediated fatty acid biosynthesis.
SAR317461 Inhibit JAK2/STAT3 Phosphorylation for Enhanced Anti-leukemia Activity.
Ginsenoside Rb1 Targets the HRD1-STING Axis to Mitigate Cholesterol-Induced VSMC Senescence.
Rhein attenuates oxidative stress-induced injury in human ovarian granulosa cells by inhibiting the NF-κB-TNF-α/IL-6/PTGS2 inflammatory axis.
Unraveling the Therapeutic Mechanisms of Shanzhen Mingmu Pill in Diabetic Retinopathy: An Integration of Serum Pharmacochemistry, Network Pharmacology, and Experimental Validation.
PDK4-driven lactate accumulation facilitates LPCAT2 lactylation to exacerbate sepsis-induced acute lung injury.
Acceleration of Lactate Uptake and Utilization Contributes to Neuroprotective Action of FGF21 Involved in Naturally Aging Mice.
Scutellaria baicalensis extract prevents metabolic dysfunction-associated steatotic liver disease by modulating the gut-liver axis in high-fat diet mice.
Anatid herpesvirus 1 UL51 protein is palmitoylated by DHHC9 and DHHC18 for viral replication and virulence.
Vitexin targets USP49-GRPR deubiquitination axis in medullary thyroid carcinoma therapy.
Selenium-Enriched Akkermansia muciniphila: A Novel Probiotic Bacterium for Se Supplementation.
Betaine supplementation attenuates high-Se induced insulin resistance in C57BL/6 mice.
XIAP Stabilizes DDRGK1 to Promote ER-Phagy and Protects Against Noise-Induced Hearing Loss.
Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells.
Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles.
FA-2-b-β modulates HMGB1/NF-κB/NLRP3 signaling to alleviate neuroinflammation in Alzheimer's disease.
Multi-omics mapping identifies CYBA-mediated mitochondrial dysfunction driving macrophage polarization and ferroptosis via Nrf2 pathway in atherosclerosis.
Dendritic Cell-Associated MARCKSL1 Regulates Fibroblast Differentiation During Wound Healing.
Study on the Mechanism of Paeoniflorin, an Active Component of Paeonia lactiflora Pall., in Improving Skin Pigmentation by Inhibiting the TNF-α Signaling Pathway.
β-catenin mutation reprograms ketone body metabolism to drive hepatocellular carcinoma metastasis and resistance to ketogenic therapy via transcriptional activation of OXCT1.
Rosmarinic Acid Targets AKR1B1 to Ameliorate Atherosclerosis via Vascular Endothelial Cell Energy Metabolism Regulation.
Hyaluronic acid-based reduction responsive nanoparticles for Improved anti-psoriasis effects of traditional Chinese herb monomer oleanolic acid via blocking YAP-AREG axis.
Study on the Role of the AMPK/PGC-1α Pathway in Cold-Induced Vascular Endothelial Cell Apoptosis and Uterine Damage.
Genetic variations interact with polybrominated diphenyl ether exposure to alter lipid homeostasis.
Unraveling the Molecular Mechanisms Linking Cigarette Smoke Exposure to Skin Damage.
Dendrobium officinale polysaccharide ameliorate hyperlipidemia through LKB1/AMPK and CD36/PGC-1α/UCP1 activation and gut microbiota modulation.
Natural photosynthetic system for restoring homeostasis of animal organelle interaction network.
Mechanism of platelet-rich plasma inhibiting inflammatory response, oxidative stress, and senescence in synovial fibroblasts of patients with knee osteoarthritis via UBE2C based on transcriptome sequencing analysis.
Family single-cell atlases reveal pig pregnancy and fetal growth restriction critical cell types.
Meningeal lymphatic dysfunction mediates postoperative sleep deprivation-induced cognitive decline via impaired neuroinflammatory clearance.
METTL3-regulated m6A modification modulates autophagy of placental mesenchymal stem/stromal cell by YTHDF3-mediated degradation of LncRNA GAS5 in preeclampsia.
A new candidate tumor suppressor tRF-Ser inhibits gastric cancer progression by regulating the CNBP/HSPA8 axis.
GALNT1 emerges as a potential therapeutic target in breast cancer.
FASN inactivation-induced progranulin (GRN) expression promotes lysosome-dependent cell death to suppress leukemogenesis.
Matrix Stiffness Modulates Fibroblast Paracrine Signaling to Enhance Autophagy in Keratinocytes: Implications for Wound Healing.
Phytosterol alleviates cholesterol accumulation by influencing intestinal esterification rather than competitive solubilization under dietary MUFA.
High-Intensity Interval Training Outperforms Moderate-Intensity Exercise in Hyperlipidemic ApoE⁻/⁻ Mice: A Molecular and Histological Comparison.
CCT3-mediated regulation of XPO1/RB1 axis stability promotes cellular senescence and tumor progression in clear cell renal carcinoma.
PCMTD1-127aa suppresses osteosarcoma progression by competitively binding to USP10 to promote c-MYC degradation.
Ferulic Acid Alleviates Chemotherapy-Induced POI by Targeting the Grp78 and Perk-eIF2α-ATF4-CHOP Pathway to Attenuate Endoplasmic Reticulum Stress.
Pathological Characteristics of the Lung and Brain in Cotton Rats and BALB/c Mice Infected with Respiratory Syncytial Virus.
Hijacking Actin-Pre-Liquid-Liquid Phase Separation Suppresses Malignant Tumor Invasion and Growth.
LINC01996 suppresses non-small cell lung cancer proliferation and metastasis by orchestrating the miR-12115/CNRIP1/Ras signaling axis.
Charge-Adaptive Nanoparticle Attenuates Inflammation via Targeting Neutrophil Extracellular Traps (NETs) and Breaking NETs-Macrophage Crosstalk.
Ezrin, radixin, and moesin are novel citrullinated proteins in the decidua during pregnancy†.
Programmable RNA N(6),2´-O-Dimethyladenosine Editing.
Endogenous Ceramide 24:1 Constrains Th17-Driven Neutrophilic Inflammation by Antagonizing EP2 Signaling.
Protective Effect of Paeoniae Radix Alba Carbonisata on Hepatic Amyloidosis by Regulating Calcium Homeostasis.
Acrylamide exposure induces neurotoxicity via the PI3K/Akt/NF-κB pathway: Evidence from network toxicology and experimental validation.
Polystyrene nanoplastics trigger mitochondrial and metabolic reprogramming in cardiomyocytes: Evidence from integrated transcriptomic and metabolomic analysis.
Therapeutic effects of low-intensity transcranial focused ultrasound stimulation on ischemic stroke in rats: An in vivo evaluation using electrical impedance tomography.
USP52 promotes clear cell renal carcinoma progression by deubiquitinating and stabilizing CORO6.
Melanocyte proliferation gene 1 regulated metabolic reprogramming in acute myocardial infarction based on the AMPK/mTOR pathway.
Hyperoside impairs mitochondrial respiration in chronic myeloid leukemia by promoting STUB1-mediated ubiquitination and degradation of NOX4.
Nicotine Activates PI3K/AKT Pathway to Induce Cellular Proliferation, Invasion, and Migration in HPV-16 Positive Cervical Cancer SiHa Cells.
Haizao Yuhu Decoction Inhibits Goiter via p53 Pathway-Induced Apoptosis: Metabolomic and Cellular Assay Analysis.
Untargeted Metabolomic Study of the Anti-HBV Effects of Erythrocentaurin In Vitro and In Vivo Using UPLC-Q-TOF/MS.
Unveiling the prognostic and immunotherapeutic role of Tregs in lung cancer using integrated analysis of single-cell and bulk RNA-sequencing.
Aldh3a1-mediated detoxification of reactive aldehydes contributes to distinct muscle responses to amyotrophic lateral sclerosis progression.
Glutathione-depleting mitochondria-targeting nanodrugs for stress amplification and immune activation via synergistic photodynamic therapy and cuproptosis.
Urinary exosomes aggravate diabetic kidney disease by inducing podocyte ferroptosis via the miR-217/SIRT1/Nrf2 pathway.
Atractylenolide I ameliorates acute-on-chronic liver failure (ACLF) by promoting autophagy and preserving mitochondrial function through mTOR inhibition.
Tannic acid inhibits viral replication by disrupting nucleocapsid condensation.
Scutellarin modulates Nrf2 to alleviate inflammation, pyroptosis, and ferroptosis in acetaminophen-induced hepatotoxicity.
Echinacoside modulates PARP14-GLUD1 axis to mediate energy metabolism reprogramming and mitochondrial function in diminished ovarian reserve.
Astragaloside IV alleviates post-traumatic cytotoxic edema via inhibition of AQP4 expression and subcellular localization.
XIAOSHUI formula inhibits malignant pleural effusion by targeting the STC1/p65/CXCL5 axis to reprogram tumor-associated macrophages.
Paeonol inhibits the progression of endometrial cancer by affecting TRIM26-mediated LDHA ubiquitination modification.
Salvianolic acid C, a novel pyroptosis inhibitor, attenuates podocyte injury in diabetic kidney disease through regulating miRNA-21/A20 pathway.
Design, synthesis, and pharmacological evaluation of novel PROTAC degraders targeting 11β-HSD1 for metabolic disease intervention.
Integrated network pharmacology and AlphaFold modeling reveal ESR1 as a key target of Huanglian Jiedu decoction for ameliorating sepsis-induced coagulopathy.
Tibetan medicine Bawei Chenxiang Wan attenuates chronic mountain sickness by targeting the AKT/FOXO3a/CAT axis to inhibit oxidative stress.
Role of PTP1B in coordinating synaptic plasticity and ferroptosis: A mechanism underlying the antidepressant effect of spinosin from Ziziphus jujuba Mill. var. spinosa (Bunge) Hu ex H. F. Chou.
ACOT8-mediated palmitate accumulation promotes M1 macrophage polarization in renal ischemia-reperfusion injury via activation of the cGAS-STING pathway.
Neferine ameliorates psoriasis through inducing oxidative stress-mediated keratinocyte apoptosis and suppressing inflammatory response via the Keap1-Nrf2 pathway.
Propyl gallate mitigates diabetic liver injury via suppressing SLC7A11/GPX4-mediated hepatic ferroptosis and modulating gut-liver axis.
Endothelial Foxp1 overexpression inhibits endothelial-to-mesenchymal transition via suppressing Notch pathway activation to attenuate valvular calcification in chronic kidney disease.
Primase subunit 2 regulates the proliferation and apoptosis of gastric cancer cells via MCM7/CDK4 and Bax/Bcl-2 pathways.
Design, synthesis and biological evaluation of testosterone derivatives as potential anti-tumor and anti-inflammatory agents.
Microglial efferocytosis dysfunction contributes to depression-like behaviors and cognitive impairment in aged mice following chronic sleep deprivation.
Abnormal FKN-CX3CR1-NR signal triggers hippocampal synaptic dysfunction in rheumatoid arthritis-related depression.
Pyrimethamine regulates m6A modification of CCND1 via METTL14/YTHDF2 to inhibit hepatocellular carcinoma.
Characterization of a polysaccharide from Rhodobryum giganteum and its activation effects on TLR4/PI3K-Akt/IκBα pathway.
Role of AQP1 in the Ameliorating Effect of Electroacupuncture in a Rodent Model of Visceral Hypersensitivity.
6-Gingerol alleviates NNK-induced lung carcinogenesis by boosting antioxidation and reducing inflammation.
Disruption of the nucleocapsid-RNA condensation by punicalagin is a broad-spectrum antiviral approach.
Exploring the role of metformin in high fluoride ingestion-induced bone lesions.
LRRC8A Mediates Ischemic Neuronal Injury by Potentiating NMDA Receptor Activity and Activating Mitochondrial Apoptotic Pathway.
Cyprinid Herpesvirus 2 Infection Activates IL-17C/NF-κB/IFNγ Antiviral Signalling Axis in Caudal Fin Cells of Carassius auratus Gibelio.
Aspirin's therapeutic mechanism against diesel particulate matter-induced lung injury revealed by network pharmacology and experimental models.
USP28 Promotes Osimertinib Resistance in H1975 NSCLC Cells by Deubiquitinating and Stabilizing SIRT1.
m6A-Modified BASP1 Regulates IL6 Expression to Induce TAM Infiltration to Promote Gastric Cancer Progression.
Metformin alleviates presbycusis by activating the SIRT1/PINK1/GPX4 pathway in vitro and in vivo.
Targeting aldose reductase in pulmonary fibrosis: Blocking de novo fatty acid synthesis halts pro-fibrotic M2 polarization.
Glutamine modified lipid nanoparticles loaded with GPX4 siRNA for cervical cancer targeting.
Intermittent Fasting Alleviates Anesthesia/Surgery-Induced Delirium-Like Behavior in Aged Mice by Remodeling Gut Microbiota.
Kaempferol Mitigates CSE-Induced Lung Injury and Epithelial Cell Ferroptosis via Modulating Nrf2/NCOA4/GPx4 Axis.
ATF4 transcriptional regulation of OMD and STC2 drives vascular calcification progression via the PI3K/AKT pathway.
Transcriptomic profiling reveals the role of Hedgehog signaling as a biomarker and in the pathogenesis of Ménétrier's disease.
Systemic LINE-1 RNA in Plasma Extracellular Vesicles Drives Neuroinflammation and Cognitive Dysfunction via cGAS-STING Pathway in Aging.
CDX2 Promotes Hepatic Specification of hiPSC-derived Endoderm Through the PI3K-Akt-GSK3β Pathway for Improved Therapeutic Efficacy.
Thallium exposure disturbs gut microbiota composition, metabolic function, and host gut energy metabolism in aged mice.
Zinc Deficiency Aggravates High-Fat Diet-Induced Renal Injury by Regulating Oxidative Stress and Inflammation via the Nrf2/HO-1 Pathway.
Verticinone inhibits cell growth and induces pyroptosis via regulating AKT pathway in papillary thyroid cancer.
Unraveling the active ingredients and molecular mechanisms of Qinghua Changyan granule against irritable bowel syndrome with diarrhea: Effects on gut microbiota and glutamine transport via an integrative approach combining UHPLC-MS/MS and experimental verification.
Isomeranzin activates Gnas-AMPK signaling to drive white adipose browning and curb obesity in mice.
Pharmacological inhibition of PGK1 by genipin reduces inflammation and oxidative damage in osteoarthritis.
Ononin promotes bone marrow-derived mesenchymal stem cells survival via SIRT6/Nrf2 signaling for myocardial infarction repair.
Qingqi Liangying formula inhibits brain endothelial cell pyroptosis via NLRP3/caspase-1/GSDMD in sepsis-associated encephalopathy.
Carnosic Acid Mediates Production of Reactive Oxygen Species to Regulate Mitogen-Activated Protein Kinase Pathway Phosphorylation and Induce Apoptosis in Human Breast Cancer Cells.
Batatasin III alleviates slow transit constipation by regulating gut microbiota and inhibiting the NLRP3-IL-1β pathway.
REEP1 Accumulation Disrupts ER Integrity and Drives Spinal Motoneuron Degeneration in Distal Hereditary Motor Neuropathy.
Inhibiting Liver-Derived C3 Protein Rescues Anesthesia/Surgery-Induced Cognitive Impairment, Synaptic Disorders, and Microglial Phagocytosis.
ZDHHC2-Dependent Palmitoylation Dictates Ferroptosis and Castration Sensitivity in Prostate Cancer via Controlling ACSL4 Degradation and Lipid Peroxidation.
Renal-targeted exosomes inhibiting miR-182-5p for treatment of renal ischemia-reperfusion injury.
Rhapontigenin alleviates cellular senescence and physiological aging by upregulating sirt1 and promoting autophagy.
RNA-coupled CRISPR screens reveal ZNF207 as a regulator of LMNA aberrant splicing in progeria.
Acupuncture ameliorates diet-induced obesity via the vagal-GLP-1-ARC circuit: neural mechanism of anorexigenic action.
Time-resolved multiomics profiling reveals chromatin O-GlcNAc modification promotes senescence-associated transcriptional program.
GPR40 Attenuates Age-Related Macular Degeneration by Suppressing Retinal Microglial NLRP3 Inflammasome Activation Via ERK Signaling.
CGRP/TSP1 Signaling Dampens Corneal Inflammation and Fibrosis by Targeting A2M During Corneal Stromal Wound Healing.
Low-dose ciprofol attenuates motor dysfunction in PD mice by inhibiting NLRP3 inflammasome activation.
Effects of Blue Light Exposure on Hepatic Inflammation and Gut Microbiota in Mice Consuming a High-Fat, High-Fructose Diet.
ZM-306416 prevents ovariectomy-induced bone loss by promoting osteoblastogenesis and inhibiting osteoclastogenesis.
Decoding Gujin Luyan Xuming decoction: How ancient wisdom meets modern science in promoting angiogenesis to ameliorate cerebral infarction.
Cornuside ameliorates LPS induced cognitive dysfunction and microglial NLRP3 inflammasome activation by enhancing Sirt1-mediated autophagy.
Dictamnine inhibited keratinocyte hyperproliferation and alleviated psoriasis-like dermatitis via blocking HIF1A-mediated ferroptotic pathway.
Network pharmacology approach and experimental validation of Lamei pills in treating ischemic stroke based on UHPLC-QE-MS.
Buyang Huanwu decoction promotes post-stroke white matter repair via TREM2-Dependent microglial phagocytosis and IGF1 secretion.
Cldn11 deficiency aggravates osteoarthritis by inhibiting Notch signalling in a Tspan5-dependent manner.
Indirect ubiquitination independent of endogenous ubiquitination machinery for targeted protein degradation.
Muscle RING finger-1 facilitates skeletal muscle regeneration via regulating myoblast proliferation and differentiation.
Tanshinone IIA accelerates diabetic wound healing via suppression of macrophage NLRP3 inflammasome activity.
Hypoxic glycolysis-driven histone lactylation activates NHE7 to promote endometrial cancer progression via COX6C-mediated endoplasmic reticulum stress.
Multi-omics analysis identifies TBCB as a therapeutic target in sepsis-induced liver injury.
Thrombomodulin protects against acute vascular and multiorgan injury in sickle cell disease.
SPIB suppresses protective autophagy via the IFIT2/PINK1/Parkin axis to promote anoikis in colorectal cancer.
UTY coordinates with UTX to repress NK cell development and maturation in males.
Positive feedback regulation between USP8 and Hippo/YAP axis drives triple-negative breast cancer progression.
Betaine Inhibits Ferroptosis After Intracerebral Hemorrhage by Activating the Nrf2/HO-1 Pathway.
Revealing the anti-tumor mechanisms of aromatic oil from Amomum villosum through integrated network pharmacology, bioinformatics, machine learning, single-cell sequencing, and cell experiments.
Strategically isolated bacteriophages targeting ETEC K88 (F4) alleviate post-weaning diarrhea in piglets via modulation of gut microbiota and inflammatory responses.
Comprehensive pan-cancer analysis reveals SH3GLB1 is a novel prognostic biomarker with immunomodulatory potential.
Ginseng Polysaccharides Protect Against Endoplasmic Reticulum Stress-Induced Damage via PI3K/Akt Signalling Pathway in Bovine Ovarian Granulosa Cells.
Liraglutide Ameliorates Injury-Related Vascular Repair by Activating Autophagy Through Modulation of the PI3K-mTOR Signaling Pathway.
Role of gut microbiota in lead-induced neural damage in diabetic mice.
Neutrophil extracellular traps induce hepatocyte pyroptosis via CCDC25 in sepsis-associated liver injury.
FDCA Attenuates Neuronal Ferroptosis and Reduces Hemorrhagic Transformation After Ischemic Stroke with High Glucose.
Dunaliella salina-Loaded Diosmetin Carriers Alleviate Oxidative Stress and Inflammation in Cisplatin-Induced Acute Kidney Injury via PI3K/AKT Pathway.
Investigation of BECN1-Mediated Autophagy Mechanisms Triggered by External Stimuli in Clinical Mastitis of Dairy Cows.
Huazhuo Sanjie Chubi Decoction attenuates gouty arthritis and kidney fibrosis by regulating urate transporters and JAK2/STAT3 pathway.
7-dehydrocholesterol promotes CCL2-secretion from porcine skeletal muscle satellite cells, enhancing the migration of preadipocytes.
Curzerene Ameliorates Depression-Like Behaviors and Cognitive Impairment by Modulating the Gut Microbiota and HMGB1/RAGE/TLR4 Pathway.
Contribution of ferroptosis and SLC7A11 to light-induced photoreceptor degeneration.
Jubang Huashi Yin and its active component cynaroside alleviate excessive inflammation in COVID-19 by inhibiting IKKβ activity.
Lycium barbarum polysaccharide LBP3 alleviates 5-Fluorouracil-induced intestinal injury via a mechanism associated with activating Nrf2 and improving mitochondrial function.
STING deficiency alleviates ischemia-reperfusion injury via JAK2/STAT3-mediated macrophage polarization and autophagy.
Celastrol nanomedicine eye drops restore redox homeostasis and prevents keratoconus progression via PI3K/AKT/AP-1 signaling.
PHGDH-dependent serine metabolism in astrocytes: A key regulator of oxidative stress and pyroptosis in cerebral ischemia-reperfusion injury.
Atomic-level regulation of the coordination structure in single-atom Fe nanozymes for tumor catalytic therapy.
Tryptophan and polyamine metabolism dysregulation serves as an early marker of high-fat diet-induced glucose intolerance.
Selective autophagic degradation of glycolytic activator PFKFB3 contributes to maintaining intestinal epithelial barrier in inflammatory bowel disease.
BACH1 is stabilized by vitamin E and attenuates the formation of hypertrophic scar through the Wnt/β-catenin pathway.
Shionone ameliorates pulmonary fibrosis by activating mitophagy via PINK1-Parkin pathway.
Diagnostic potential of neutrophil extracellular traps in ulcerative colitis: a gene-based predictive model.
Long non-coding RNA STMN1P2 promotes breast cancer doxorubicin resistance by inhibiting pyroptosis through the hnRNPU-EZH2-TARF6-MALT1-caspase-1 pathway.
BMP1 inhibitor UK383367 improves MI-induced cardiac remodeling and fibrosis in mice via ameliorating macrophage polarization and mitochondrial dysfunction.
Neuroprotective Effects of Salvia Miltiorrhiza-Derived Extracellular Nanovesicles in Traumatic Brain Injury.
Therapeutic Potential of Curcumin in Diabetic Cardiomyopathy: Modulation of Pyroptosis Pathways.
Glycyrrhizic acid-loaded biomimetic hybrid liposomes targeting inflammatory cascades and PD-1/PD-L1 pathway to reverse neuroinflammation-driven cognitive decline.
Dynamin-Related Protein 1-Dependent Disruption of Mitochondrial Homeostasis Drives Blue Light-Induced Epithelial-Mesenchymal Transition in Retinal Aging.
NMNAT1 Activates Autophagy to Delay D-Galactose-Induced Aging in Cochlear Hair Cells.
3-Deoxy-3β-syringoylamino-betulinic acid Reduces Breast Tumor Growth and Lung Colonization, With Associated Downregulation of the RAS/RAF/MEK/ERK Pathway.
Health risk assessment of emerging PFOS substitute 8:2 Cl-PFESA: evidence from mouse spermatogenesis and derivation of a safe exposure threshold.
Differentiating Damp-Heat and Cold-Damp Diarrhea in Rat Models via Gut Microbiota Dysbiosis and Short-Chain Fatty Acid Profiling.
Liquiritigenin alleviates high-salt diet-induced heart damage by inhibiting TGF-β1/Smad signaling and reducing inflammation and fibrosis.
HMMR is a novel prognostic marker and a potential therapeutic target for colon cancer.
Brd4 BD1 Domain Antagonism of MS436 Preserves Blood-Brain Barrier Integrity via Rnf43/β-Catenin Signaling Pathway.
Genome-Wide CRISPR Screen Reveals PIK3CA Inhibition Enhances Lipid Nanoparticle-Mediated siRNA Delivery.
CRISPRi Screening Identifies Essential E. coli Virulence Factors for Placental Barrier Breach in a Maternal-Fetal Infection Model.
Unraveling the Cold Property of Gardeniae Fructus: Material Basis and Biological Mechanisms.
Grass carp reovirus VP35 hijacks DHX15 into phase-separated inclusion bodies to evade host antiviral immunity.
SERPINE1-Driven MAPK Activation Enhances Cuproptosis Resistance and Angiogenic Potential in Colorectal Cancer.
Citrate-coated Prussian blue nanozyme hitchhikes neutrophils to ameliorate calcium oxalate crystal-induced kidney injury via inhibiting pyroptosis and NETosis.
Ginsenoside Rg5 Targets PRDX1 to Disrupt Redox Homeostasis and Induce Mitochondria-Dependent Apoptosis in Human Hepatocellular Carcinoma HepG2 Cells.
Chicory Extract Alleviates Anthracycline-Induced Cardiotoxicity by Inhibiting Mitochondrial Damage via the UCP2/NLRP3 Pathway.
Integrated metabolomics and 16S rRNA sequencing reveal the mechanism of total flavones of Abelmoschus manihot (L.) Medic against liver fibrosis.
DCC-2036 induces repolarization of TAMs to M1 type and enhances CD8(+) T cell immunity in TNBC.
Macrophage-Mimicking Biomimetic Microbubbles for Early Ultrasound Molecular Imaging of Acute Rejection in Heart Transplantation.
Targeting TFAM K76 acetylation attenuates mitochondrial dysfunction and kidney injury in diabetic kidney disease.
ROS-Scavenging Bamboo-Derived Carbon Dot-Methotrexate Nanocomposite Ameliorates Rheumatoid Arthritis through Dual Therapeutic Mechanisms.
A TRIM21-UCHL3-ITCH-SIPA1 axis promotes colorectal cancer growth and metastasis.
Integrative analysis of single-cell RNA sequencing, bulk RNA sequencing, and proteomic data identified NOTCH3 as a hub gene contributing to human intervertebral disc fibrosis.
NEAT1 drives SARS-CoV-2 N protein-induced inflammation, metabolic reprogramming, and mitochondria-ER stress crosstalk.
Triptonide Suppresses AML via PI3K/AKT Signaling: A Network Pharmacology Approach Validated by Molecular Docking and Experimental Studies.
FGF4 activates FGFR1 - PI3K/AKT signaling to enhance Clec10a-mediated intracellular myelin debris processing and promote spinal cord repair.
Psoralen Promotes Direct Chemical Reprogramming of Mouse Embryonic Fibroblasts into Osteoblast-like Cells.
Integration of Bulk and Single-Cell Transcriptomics Reveals Prognostic and Immunological Roles of MTHFD2 in Clear Cell Renal Cell Carcinoma.
Monocyte-macrophage SAMHD1 alleviates EAMG by modulating the cGAS-STING pathway.
Foodborne PET Microplastic Contamination Compromises Intestinal Barrier through a Mitochondrial-AMPK-DNA Damage Pathway.
Supramolecular delivery of senolytics enables targeted anti-senescence therapy and accelerated fracture healing.
Fascin-1 Limits Secondary Damage by Preventing Oxidative‑Stress‑Induced Microglial Death After Spinal Cord Injury.
LL37-induced mitochondrial stress activates the mtDNA/cGAS/STING pathway to promote mast cell-mediated rosacea inflammation.
Mitochondrial uncoupling sensitizes gastric cancer cells to elesclomol-induced cuproptosis via FDX1/DLAT upregulation.
LBPs NPs suppress breast cancer progression by inhibiting YAP1 expression to induce ferroptosis and alter energy metabolism.
Asporin regulates glycolysis and stemness of gastric cancer cells.
Integrated bioinformatics and experimental validation identify CCDC78 as a prognostic biomarker in colon adenocarcinoma.
ZIKV envelope protein is a strong blocker of early directional differentiation in the neural lineage.
Circadian disruption induces cognitive impairment through tryptophan-5-HT metabolic pathway dysregulation.
Zhichuanling oral liquid attenuates airway inflammation in asthma by targeting the STIM1/CHOP/JNK axis.
Yinhuo Tang alleviates ionizing radiation injury via modulating PI3K-Akt signaling and metabolomics in mice.
Qingyu Yangjing formula ameliorates cyclophosphamide-induced oligoasthenospermia by regulating the hypothalamic-pituitary-gonadal axis and inhibiting testicular oxidative stress and apoptosis in rats.
Prebiotic augmented nanozyme-armored probiotics reprogramme the gut microenvironment for synchronous treatment of colitis and sepsis via antioxidant defense.
Trimethylamine-N-oxide disrupts spermatogenesis by inducing mitochondrial oxidative stress injury through Hippo signaling.
An intrabody targeting PHD2 protects mice against acetaminophen-induced liver injury by attenuating ferroptosis.
Charge-flip nanoparticles loaded with TAK1 inhibitors inhibit retinal neovascularization.
Bromodomain-containing protein 4 knockdown promotes neuronal ferroptosis in a mouse model of subarachnoid hemorrhage.
Overconsumption of fructose aggravates acute GVHD by inducing gut dysbiosis and promoting macrophage-mediated inflammatory response.
Gut-confined fullerene reprograms lactate metabolism to Rescue hypoxia-induced exercise intolerance.
Organelle stress in pyometra: Molecular evidence of endoplasmic reticulum stress and mitochondrial dysfunction.
KLK8 promotes cartilage degradation and pyroptosis in osteoarthritis by activating the NF-κB and NLRP3 inflammasome pathways.
P2Y2 receptor as a favorable predictor of gastric cancer.
Tussilagone attenuated cigarette smoke-induced chronic obstructive pulmonary disease through regulating Nrf2 and NF-κB/NLRP3 inflammasome via directly targeting cysteine 434 of KEAP1.
Inhibition of GPR75 Alleviates Lipid Metabolism by Activating the AMPK-SIRT1 Signaling Pathway In Vitro and In Vivo.
Identification of a Novel Mitochondrial-Related Gene Signature for BMSCs in Osteoporosis Combining Single-Cell and Bulk Transcriptome Data.
Serine Promotes Inflammatory Macrophage Polarisation in Periodontitis via NAD(+) Signalling.
Ginkgetin inhibits non-small cell lung cancer via the HSP90-AKT signaling pathway.
An alkaline nanosized platelet vesicle-based hydrogel for the treatment of osteoporotic bone defects.
Transdermal siRNA delivery via biomineralized nanoparticle-incorporated microneedles modulates cuproptosis-ferroptosis interaction for psoriasis therapy.
Dual-responsive PDA-HP hydrogel enables mitochondria-targeted mild photothermal therapy for spinal cord repair.
Panax notoginseng saponins protect the blood-brain barrier against oxidative stress by activating the Akap12-PI3K/AKT-AQP1 signaling axis.
Laminarin attenuates neuroinflammation in MPTP-induced Parkinson's disease mouse model via inhibiting dectin-1/Syk/NF-κB signaling.
Hydrogen-releasing electroactive nerve guidance conduits promote peripheral nerve regeneration by remodeling the microenvironment.
The Dual Role of Gastrodin in Spinal Cord Injury: Microglial Phenotype Switching and Neuronal Survival via PI3K/AKT Activation.
PUM2 knockdown regulates the expression and alternative splicing of genes associated with myocardial fibrosis in H9C2 cells.
Senescence-Driven Remodeling Defines an Aggressive and Immunomodulatory Subtype of Endometriosis.
Tartrate-Resistant Acid Phosphatase 5 (TRAP/ACP5) aggravates atherosclerosis by regulating macrophage polarization and promoting ferroptosis.
Therapeutic potential of Cistanche against Parkinson's disease via regulating circulating inflammation: Insights from Mendelian randomization, molecular docking, and in vivo studies.
The regulatory role of circGDI2 in hepatocellular carcinoma proliferation and glycolysis with the involvement of m6A modification.
Neuroprotective effects of DPP-4 inhibitors sitagliptin and vildagliptin in Parkinson's disease via autophagy modulation.
Celastrol disrupts the inflammatory feedback loop driven by Tenascin-C⁺ fibroblast subtype in psoriasis: Insights from single-cell RNA sequencing and experimental validation.
Geum japonicum Thunb. var. Chinese-P.decorata H.Andres herbal pair ameliorates CIRI-induced neuronal injury by facilitating mitochondrial transfer via the CD38/Miro1 signaling pathway.
Diosmetin alleviates hyperuricemic nephropathy by activating the BNIP3/Nrf2/GPX4 pathway to inhibit ferroptosis of renal tubular epithelial cells induced by monosodium urate crystals.
Diabetes Mellitus Facilitates Gallstone Formation Through CXCR2-NETs-Mediated Liver-Bile Barrier Damage.
Structure-Based Discovery of Novel, Highly Potent VEGFR2 Inhibitors with a Naphthalene Scaffold against a Broad Range of Solid Tumors.
Discovery, Optimization, and Biological Evaluation of 2-Cyano-2-(9H-xanthen-9-ylidene)acetamide Derivatives as ZNF207 Inhibitors for Anti-Glioma Therapy.
Integrated multi-omics and experimental validation for identifying novel biomarkers of acute myocardial infarction.
Comprehensive pan-cancer analysis of AARS1, a newly identified lactyltransferase in human cancers.
Pan-Cancer Analysis and Functional Characterization Identify SLC15A4 as a Novel Prognostic Biomarker and Therapeutic Target.
Hyperglycemia impairs cognitive function by inducing mitochondrial damage through lactylation of LRPPRC at K223.
AnnoNet-TCMs: An annotation network-driven discovery of novel active compounds and mechanisms in traditional Chinese medicine.
Gordonibacter-associated regulatory T cell dysfunction and S100A11-mediated neural impairment in Hirschsprung's disease: a microbiota-immune-neural axis.
YWHAZ downregulated innate immune responses to RNA viruses by inhibiting the IRF3 signaling pathway.
Berberine Ameliorates Atherosclerosis by Promoting Mitochondrial Biogenesis via SIRT1/PGC-1α Signaling Pathway.
Neudesin modulates IGF1 and insulin signaling pathways by regulating the surface expression of IGF1R through a conserved WPE motif.
Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems.
Ameliorative Effect of Luteolin on H2O2-Induced Mitophagy and Apoptosis in Cardiomyocytes Through Modulation of the AMPK/mTOR Pathway.
Triggering Receptor Expressed on Myeloid Cells-2 Regulates Innate Lymphoid Cell Levels in Bleomycin-Induced Pulmonary Fibrosis.
Formation of the pre-metastatic niche by COL9A1 + cancer-associated fibroblasts via SDC4 engagement promotes multi-organ metastasis in gastric cancer.
RBM11 drives malignant progression of bladder cancer by regulating GNPDA1-PKM2 axis.
TRIM36 and CAMK2N2 regulate ferroptosis and antigen presentation in small cell lung cancer.
Alpha-ketoglutarate alleviates Cadmium-induced ferroptosis in association with enhanced mitochondrial function in testes.
BMSC-derived exosomal ANTXR1 inhibits erythroid differentiation by suppressing the TLR4/MyD88/NF-κB signaling pathway.
Pellino1 Exacerbates Diabetic Kidney Disease Through NLRP3 Inflammasome Driven Pyroptosis in Renal Tubular Epithelial Cells.
Uridine metabolism promotes lung adenocarcinoma progression by activating FBL transcription via YBX1.
Ginsenoside Rg3 synergizes with near-infrared photothermal therapy to suppress prostate cancer progression by inhibiting RAS signaling and enhancing ARL11-mediated macrophage reprogramming.
Quercetin alleviates imatinib-induced premature ovarian insufficiency by regulating mitophagy via the ROS/JNK/c-JUN pathway.
Persistent testicular glycogenolysis and active lipid metabolism during torpor in hibernating Siberian chipmunks.
Methylation of tenascin XB mediated by methyltransferase-like 3 can effectively suppress neural injury and cellular apoptosis induced by ischemic stroke.
Mosaic Inverted Hemagglutinin Extracellular Vesicle Vaccines Elicit Protective Systemic and Mucosal Immunity against Heterosubtypic Influenza Infection.
NT5DC2 inhibits ferroptosis by stabilizing ACSL3 in bladder cancer.
MELK is Required for G2/M Phase Progression in Cortical Progenitors: Insights from Rare ASD-Associated Variants.
Heme oxygenase-1-enriched tolerogenic dendritic cell-derived exosomes attenuate lupus nephritis by restoring immune balance and iron homeostasis.
PIM1 Inhibition Alleviates Aspergillus fumigatus Keratitis by Regulating DDX41-Mediated STING Signaling Pathway.
An indoloquinolinone 3a alleviates lipopolysaccharide-induced acute lung injury by modulating the NF-κB and AMPK/Nrf2 signaling pathways.
Targeting HSPB1 inhibits tumor growth and abrogates Treg-mediated tumor immunosuppression.
Di-(2-ethylhexyl) phthalate induces endometriosis by modulating IGF-1 m6A methylation via the intestinal Odoribacter-butyric acid axis in female rats.
Na(+)/K(+)-ATPase Modulates Purinergic P2X3 Receptor Function to Drive Bone Cancer Pain.
Silencing of MiR-329-3p Protects against Myocardial Ischemia-Reperfusion Injury by Regulating the Wnt/β-catenin Pathway via Nemo-Like Kinase.
Carrier-Free Peptide-Daunorubicin-Small Interfering RNA Nanoassembly for Targeted Therapy of Acute Myeloid Leukemia.
A Hepatic Oxidative Metabolite of Palmatine Ameliorates DSS-Induced Ulcerative Colitis by Regulating Macrophage Polarization Through AMPK/NF-κB Pathway.
Quercetin, a Natural Dietary Flavonoid, Emerges a Novel USP7 Inhibitor with Anti-colorectal Cancer Effects.
Mycobacterial antigen Ag85B restrains Hodgkin lymphoma tumor growth by inhibiting autophagy.
Splicing factor PTBP1 promotes hepatocarcinogenesis via oncogenic splice-switching of MAPT.
Qizhi Kebitong Formula Ameliorates Sciatic Nerve Injury in Streptozocin-induced Diabetic Mice through PERK/ATF4/CHOP Endoplasmic Reticulum Stress Signaling Pathway.
Hsa_piR_016975 Is a Novel Target of Nanotherapy that Boosts Hepatoma Progression and Sorafenib Resistance by Abating Maspin/GPX4-Mediated Ferroptosis.
Ginsenoside Rh2-Pretreated Mesenchymal Stem Cell Exosomes Ameliorate Collagen-Induced Arthritis via N6-Methyladenosine Methylation.
A Novel Hypoxia-related lncRNA Risk Score Model for Prognosis Evaluation of Clear Cell Renal Cell Carcinoma.
A method for isolating and cryopreserving intact mitochondria with improved integrity and functionality.
Roxadustat: A catalyst for diabetic wound healing through re-epithelialization and angiogenesis.
DARS2 Promotes Bladder Cancer Progression by Enhancing PINK1-Mediated Mitophagy.
Linking Cellular Senescence to Vascular Pathology: The Diagnostic Potential of Superoxide Dismutase 2 in Aortic Dissection.
Dietary DHA Regulated the Androgen Production in Male Chinese Tongue Sole Cynoglossus semilaevis.
Multiomics Identifies Potential Biomarkers in Ankylosing Spondylitis Bone Formation.
Imbalance of Bone Homeostasis Caused by Nrf2 Deficiency Leads to Bone Loss in OVX Rats.
Systematic Analysis of an Immune-Related Gene Signature for Predicting Prognosis and Immune Characteristics in Primary Lower Grade Glioma.
Elucidating the Therapeutic Mechanism of Danggui Liuhuang Decoction in Hyperthyroid Kidney Disease: An Integration of Network Pharmacology and Metabolomics.
Astaxanthin Mitigates Dextran Sulfate Sodium-Induced Colitis in Mice by Repairing the Intestinal Barrier, Regulating Specific Intestinal Flora, and Reducing Inflammatory Cell Infiltration.
Identification of Core Senescence-Related Genes and Characterization of Comprehensive Immune Landscape in Intervertebral Disc Degeneration.
Active peptides of TSP-1 inhibit retinal angiogenesis through the CD36 pathway in a rat model of choroidal neovascularization.
The up-regulation of TGF-β1 by miRNA-132-3p/WT1 is involved in inducing leukemia cells to differentiate into macrophages.
RETRACTED: Short communication: Upregulation of hypoxia/reoxygenation-induced Shc3 by downregulated miR-455-5p, suppresses trophoblast invasion and is associated with placental inflammation and angiogenesis in preeclampsia.
ADH5 inhibits proliferation but promotes EMT in non-small cell lung cancer cell through activating Smad2/Smad3.
Convallatoxin inhibits proliferation and angiogenesis of glioma cells via regulating JAK/STAT3 pathway.
Gelatin/Poly (Lactic-Co-Glycolic Acid)/Attapulgite Composite Scaffold Equipped with Teriparatide Microspheres for Osteogenesis in vitro and in vivo.
Layered Double Hydroxide Nanoparticles Loaded with Resveratrol Inhibit Glycolysis and Show Efficacy in the Treatment of Breast Cancer.
TET1 Alleviates Cigarette Smoke Induced Bronchial Epithelial Cell Apoptosis Through Upregulating Nrf2.
Quercetin-Loaded Nanoparticle-Modified Decellularized Tissue-Engineered Vascular Graft Regulates Macrophage Polarization and Promotes In Vivo Graft Remodeling.
Honeysuckle-Derived Exosome-Like Nanovesicles Protect Against Acute Liver Failure by Modulating Gut Microbiota.
MXene-Mediated Nanocarrier Delivery Enhances the Chondroprotective Effects of Quercetin in Experimental Osteoarthritis.
Over-expressed Phospholamban in Cancer-associated Fibroblasts Is a Driver for CMS4 Subtype Colorectal Cancer Formation.
Hepatic Stellate Cell TM4SF1 Accelerates Hepatic Fibrosis Progression via Interacting With the Tyrosine Kinase c-Src.
Integrating Clinical Multi-Omics, Machine Learning, and Molecular Docking Strategies to Reveal the Mechanism of Yiqi Huoxue Prescription in the Treatment of Ischemic Heart Failure.
Allicin Aplealleviates Gouty Arthritis by Regulating the Gut-Joint Axis, Reducing XOD Activity, Inhibiting Oxidative Stress, and Suppressing NLRP3 Inflammasome Activation.
Puerarin Ameliorates the Ferroptosis in Diabetic Liver Injure Through the JAK2/STAT3 Pathway Inhibition Based on Network Pharmacology and Experimental Validation.
Magnesium Isoglycyrrhizinate Alleviates Alectinib-Induced Hepatotoxicity by Inhibiting Mitochondrial Damage-Mediated Pyroptosis.
Mechanism of the Traditional Chinese Medicine Simiao Biejia Decoction Improves the Diabetes Mellitus-Induced Erectile Dysfunction in Rats.
TRAP1 Improves Diabetic Retinopathy by Preserving Mitochondrial Function.
Research on the correlation between gut microbiota and brain cognitive function under chronic hypoxia at high altitude.
Disulfidptosis-Related Genes as Novel Biomarkers and Therapeutic Targets in Dilated Cardiomyopathy.
Xuebijing Injection Alleviates Sepsis-Induced Acute Lung Injury by Inhibition of Cell Apoptosis and Inflammation Through the Hippo Pathway.
AIM2-Driven Inflammation in Periodontitis: Mechanisms and Systemic Implications.
COMMD1 Regulates Osteoclast Differentiation in Talaromyces marneffei-Induced Osteomyelitis via the NF-κB Pathway.
Modified Xi-Jiao-Di-Huang Decoction Alleviates Sepsis via Regulating Macrophage Polarization by Inhibiting the PIM2/NF-κB Pathway.
Astragaloside IV Improves Cognitive Impairment by Reducing β-Amyloid and Tau Protein Deposition in Hippocampal Tissue of db/db Mice: A PET/CT Imaging-Based Study.
Association Between Proteasome 26S Subunit, Non-ATPase 3 Methylation and Insulin β Cell Apoptosis in Type 2 Diabetic Mellitus.
MCC950 Alleviates Experimental Autoimmune Neuritis by Inhibiting NLRP3 Inflammasome Activity and Down-Regulating Interleukin-23/Interleukin-17 Axis Expression.
Angiotensin-(1-7) Inhibits Angiogenesis and Alleviates Joint Damage in CIA Mice via the Hippo-YAP Pathway.
Low-Frequency (1 Hz) Repetitive Trans-Spinal Magnetic Stimulation Attenuates NLRP3-Driven Neuroinflammation and Enhances Motor Recovery in Spinal Cord-Injured Mice.
Comprehensive Analysis of Ferroptosis Markers in Lupus Nephritis Based on Bioinformatics Analysis and Experimental Validation.
VOPP1 as a Novel Susceptibility Gene in Rheumatoid Arthritis: Insights Into Its Mechanisms From Mendelian Randomization and Experimental Validation.
Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis.
Baicalein ameliorates cognitive decline induced by chronic cerebral hypoperfusion through the SIRT1-mediated Notch1 pathway to improve angiogenesis and suppress neuroinflammation.
Network Pharmacology and Experimental Validation-based Investigation of the Underlying Mechanism of Yi-Yi-Fu-Zi-Bai-Jiang-San of Nasopharyngeal Carcinoma.
Implication of CDKN2A in cuproptosis through defining cuproptosis-related gene signature in ovarian cancer.
Machine learning-derived cellular senescence index for predicting prognosis and drug sensitivity in patients with renal cell carcinoma.
A stage specific NETs-related signature in alcoholic steatohepatitis: from molecular subtyping to therapeutic vulnerabilities.
Xiaoyao Pill alleviates ulcerative colitis by inhibiting ferroptosis of enterocytes via activating Nrf2/Gpx4 signaling pathway.
Association of genetically instrumented HMGCR inhibition with the therapeutic role of prostate cancer: a Mendelian randomization study and supporting in vitro experiments.
Effect of gentiopicroside on endogenous formaldehyde homocysteine-pathway related proteins in rats with non-alcoholic steatohepatitis.
Pan-cancer analysis and experimental verification of its roles and clinical significance of SLC2A3 in kidney renal clear cell carcinoma.
Coreopsis tinctoria Nutt. attenuates ultraviolet A photodamage by suppressing endoplasmic reticulum stress-induced apoptosis via Nrf2 crosstalk.
Thymoquinone and aerobic exercise mitigate HFpEF-induced cardiac injury via Apaf1/Cycs axis regulation.
CGRP restrains CD4(+) T cell responses and allergic sensitization.
Sancai Lianmei granules ameliorate neuron injury in diabetic ischemic stroke rats by inhibiting oxidative stress and inflammation.
circWWC3 enhances the progression of triple-negative breast cancer by interacting with vimentin to regulate the secretion of CSF2.
Exploring the mechanism of Qingre Yishen Xiaozheng formula in treating diabetic kidney disease via the HIF-1α/HO-1 signaling pathway: an integrated network pharmacology and experimental study.
Single-cell profiling uncovers PTPRG-driven stemness in malignant plasma cells and signatures of treatment failure in multiple myeloma.
Integrative bioinformatic and experimental analysis reveals prognostic and immunological roles of MEX3 family genes in glioma.
Inhibition of HMGB1/NF-κB signaling restores Th17/Treg balance via dendritic cell modulation in liver transplant rejection.
Isorhamnetin attenuates renal interstitial fibrosis by targeting TWEAK/Fn14-mediated epithelial-mesenchymal transition.
Zuoqing granules attenuate ulcerative colitis via macrophage polarization modulation: involvement of the PPAR-γ/NF-κB/STAT1 signaling axis.
Sarsasapogenin protects hair cells from cisplatin-induced ototoxicity by attenuating apoptosis and ferroptosis via alleviating oxidative stress.
Ailanthone induces apoptosis in U-2OS cells through the endoplasmic reticulum stress.
Comprehensive analysis of metabolic patterns in renal cell carcinoma: implications for prognosis and treatment.
Reciprocal activation between M1 macrophages and trophoblasts through CXCL9/STAT1/ZEB1/CCL2 axis promotes recurrent spontaneous abortion.
Vitamin D ameliorates prediabetic cardiac injure via modulation of the ErbB4/ferroptosis signaling axis.
Bifidobacterium depletion promotes goiter via gut-thyroid axis: evidence from Mendelian randomization and experimental validation.
Inhibition of CYP450 family 1 subfamily B member 1 (CYP1B1) expression in macrophage reduces the inflammatory response in type 2 diabetes mellitus combined with tuberculosis.
Fucoidan from Fucus vesiculosus alleviates MetALD via promoting HIF-1α ubiquitination to suppress peripheral monocyte infiltration.
Risk scoring model for lung adenocarcinoma based on PD-L1 related signature reveals prognostic predictability and correlation with tumor immune microenvironment genes was constructed.
The function of CD164 in breast cancer and its possibility as a molecular biomarker: bioinformatics analysis and experimental validation.
T cell-mediated immune surveillance conferred by latent Epstein-Barr virus genes suppresses a broad spectrum of tumor formation through NKG2D-NKG2DL interactions.
Tetramethylpyrazine enhances neuroprotection and plasticity in cerebral ischemia-reperfusion injury via RhoA/ROCK2 pathway inhibition.
Identification of mitophagy-related biomarkers in severe acute pancreatitis: integration of WGCNA, machine learning algorithms and scRNA-seq.
Enrichment of short-chain fatty acid-producing bacteria by pH-responsive sodium alginate and chitosan-encapsulated quercetin.
Toll-like receptor 3 activation enhances antitumor immune response in lung adenocarcinoma through NF-κB signaling pathway.
Lactylation prognostic signature identifies DHCR7 as a modulator of chemoresistance and immunotherapy efficacy in bladder cancer.
Identification and evaluation of a pinocembrin analog as a TRPV1 inhibitor with analgesic properties in murine pain models.
Identification of CTSC-driven progression in ESCC by single-cell sequencing and experimental validation.
Investigating the regulation of the miR-199a-3p/TGF-β/Smad signaling pathway by BSHXF drug-containing serum combined with ADSCs for delaying intervertebral disc degeneration.
In vitro study: HIF-1α-dependent glycolysis enhances NETosis in hypoxic conditions.
SIRT2-dependent CPT1A deacetylation in macrophages inhibits periodontitis.
Investigation of Fructus sophorae extract's therapeutic mechanism in atrophic vaginitis based on network pharmacology and experimental validation.
Molecular characteristics and cancer immunity of LRP1B and its relationship with the Hedgehog signaling pathway in colorectal cancer.
Trapidil attenuates diabetic cardiomyopathy via GPX3/Nrf2-mediated inhibition of myocardial pyroptosis.
Wuling capsule alleviates hyperuricaemia and protects UA- injured HK-2 cells by regulating uric acid transporter proteins.
Integrative analysis of single-cell and bulk RNA sequencing reveals the oncogenic role of ANXA5 in gastric cancer and its association with drug resistance.
Acetylcholine from tuft cells promotes M2 macrophages polarization in Hirschsprung-associated enterocolitis.
Licorice attenuates cisplatin-induced hepatotoxicity by alleviating endoplasmic reticulum stress and apoptosis.
IGFBP5 mediates the therapeutic effect of isoliquiritigenin in myocardial ischemia-reperfusion injury via AKT/GLUT4 regulated insulin resistance.
Wharton's jelly-derived mesenchymal stem cells ameliorate high altitude-induced heart injury by promoting type 2 macrophage polarization via COX2-PGE2 pathway.
Clusterin ameliorates diabetic atherosclerosis by suppressing macrophage pyroptosis and activation.
Therapeutic potential of isochlorogenic acid A from Taraxacum officinale in improving immune response and enhancing the efficacy of PD-1/PD-L1 blockade in triple-negative breast cancer.
Targeted inhibitors of S100A9 alleviate chronic pancreatitis by inhibiting M2 macrophage polarization via the TAOK3-JNK signaling pathway.
Bletilla oligosaccharides improved 5-fluorouracil-induced intestinal mucositis in mice by activating NF-κB signalling pathway and regulating intestinal microbiota.
An integrative pharmacology-based study on the pharmacological activity and mechanism of xiaoji-chenpi formula (XCF) against MAFLD.
Regulatory mechanism of ABCB1 transcriptional repression by HDAC5 in rat hepatocytes under hypoxic environment.
Hydrogen sulfide alleviates high-salt-stimulated myocardial fibrosis through inhibiting hypoxia-inducible factor-1α.
Molecular mechanism underlying cardioprotective effect of dehydroepiandrosterone on endoplasmic reticulum stress induced apoptosis in human vascular smooth muscle cells and human umbilical vein endothelial cells.
Identification and validation of neutrophil-related biomarkers in acute-on-chronic liver failure.
Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.
A strategy targeting ferroptosis for mitochondrial reprogramming and intervertebral disc degeneration therapy.
Calcium dysregulation disrupts mitochondrial homeostasis by interfering AMPK/Drp1 pathway to aggravate plaque progression and instability.
Autophagy inhibitor-sensitized artificially activated neutrophils against hepatocellular carcinoma.
Human fibrosarcoma cells selected for ultra-high doxorubicin resistance, acquire trabectedin cross-resistance, remain sensitive to recombinant methioninase, and have increased c-MYC expression.
M2-type macrophage nanovesicles regulate the inflammatory response after necrotizing enterocolitis by inducing M1 to M2-like macrophage polarization.
CDK1-driven phosphorylation networks promote glioblastoma progression via MAP1B-mediated microtubule destabilization.
Construction of a glycosylation-related prognostic signature for predicting prognosis, tumor microenvironment, and immune response in soft tissue sarcoma.
LILRA5(+) macrophages drive early oxidative stress surge in sepsis: a single-cell transcriptomic landscape with therapeutic implications.
Upregulation of stomatin is associated with poor prognosis and promotes tumor progression of orbital diffuse large B-cell lymphoma.
The anti-inflammatory effects of oridonin in resisting esophageal cancer.
SATB2 promotes radiation resistance of esophageal squamous cell carcinoma by regulating epithelial-to-mesenchymal transition via the Wnt/β-catenin pathway.
To explore the prognostic efficacy and mechanism of ABCC5 clinical scoring model in hepatocellular carcinoma.
The 12-LOX/12-HETE/GPR31 metabolic pathway promotes tumor-associated macrophage M2 polarization mediated pancreatic cancer development.
Integrative pan-cancer analysis of UCP family and experimental validation identifies UCP2 as a potential therapeutic target for glioma.
Aquaporin 2 is differentially expressed in granulosa cells of various stages of human follicles and is regulated by luteinizing hormone.
Induced neural stem cells ameliorate blood-brain barrier injury by modulating the calcium signaling pathway of astrocyte in cerebral ischemia-reperfusion rats.
Linoleic acid metabolite 13-Hydroxyoctadecadienoic acid as a biphasic ferroptosis modulator in granulosa cells: multi-omics analysis of ovine atretic follicles.
SNHG12 downregulation induces follicular dysplasia by modulating the glycolysis of granulosa cell in polycystic ovary syndrome.
Exploring the therapeutic mechanism of curcumin in spinal cord injury treatment based on network pharmacology, molecular dynamics simulation, and experimental validation.
Shockwave-driven activation of endoplasmic reticulum stress in osteoblasts to enhance bone formation under osteoporotic conditions.
JAK-centric explainable few-shot gene-expression diagnosis framework for alopecia via MultiPLIER priors and relation-style set-to-set comparison.
1-Deoxynojirimycin with theaflavins ameliorates high-fat diet-induced insulin resistance in mice by modulating the gut microbiota.
Multi-targeted inhibition of NF-κB signaling underlies the anti-osteoarthritic effects of BGJXF and its key component dehydrocorydaline.
Bioinformatics and experimental validation of ferroptosis-related genes in steroid-induced osteonecrosis of the femoral head.
Aqueous extract of Solanum americanum Mill. relieves functional constipation by modulating the enteric nervous system and gut micro-ecosystems.
Case Report: A FBN1 frameshift-and-nonsense mutation and aortic dissection in Marfan syndrome.
A pectic polysaccharide from Lycium ruthenicum Murray alleviates dextran sulfate sodium-induced colitis in mice.
Sestrin2 Regulates Mitochondrial Function and Autophagy via Nrf2/SIRT3 Signaling to Ameliorate Hypoxia/Reoxygenation-Induced Rat's Cardiomyocyte Injury.
STAT1-IFITM3 promotes autophagy in epithelial cells to control Cryptosporidium parvum infection.
Neural and molecular investigation into the paraventricular thalamus for chronic restraint stress induced depressive-like behaviors.
Knockdown of ACC1 promotes migration and invasion of U251 glioma cells by epigenetically suppressing SDH.
MAZ Coordinates With HDAC1 to Promote Hepatocarcinoma Proliferation and Metastasis Through Transcriptional Repression of CSK.
The role and mechanism of PGC-1α in oxLDL-induced ferroptosis of vascular endothelial cells.
Integrated multi‑omics analysis of liver metabolic dysregulation in ACE2 knockout mice.
Nucleotide-binding domain-like receptor protein 3 inflammasome contributes to vascular endothelial barrier dysfunction and shock after burn injury.
Activation of Sig-1R by afobazole attenuates Tollip/HMGB1-mediaded CCN2 autophagic degradation and NETs formation in sunitinib-induced cardiotoxicity in mice: Involvement of IRE 1α/ASK1/JNK/ AP-1 trajectory.
Ginsenoside Rg5 enhances Abemaciclib sensitivity in ER+ breast cancer by modulating cell cycle proteins via transcriptional and post-translational levels.
Introduced paeoniflorin reduces the main toxicity induced by diosbulbin B, the major toxic compound of Dioscorea bulbifera L.: involved inhibiting inflammation and ferroptosis.
NCOA4 inhibits glioma progression by suppressing the Sonic Hedgehog pathway and its overexpression indicates a better glioma prognosis.
Leukemia Inhibitory Factor via JAK-STAT Signaling Drives Beryllium Sulfate-Induced Epithelial-Mesenchymal Transition in 16HBE Cells.
WNK1 Alleviates Chloride Efflux-Induced NLRP3 Inflammasome Activation and Subsequent Neuroinflammation in Early Brain Injury Following Subarachnoid Hemorrhage.
Autologous Serum from Sjögren's Syndrome Patients Mitigates Ferroptosis in Hyperosmolarity-Induced Corneal Epitheliopathy.
Endoplasmic Reticulum Stress Inhibition Alleviates Tourniquet-Induced Limb Ischemia-Reperfusion Injury.
Discovery of Baicalein as a Novel Ubiquitin-Specific Protease 21 Inhibitor for the Treatment of Hepatocellular Carcinoma.
Targeted energy metabolomics analysis-based mitochondrial restoration: Nutritional intervention of dairy-derived MFG-E8 synergistic with egg yolk phosphatidylcholine in skeletal muscle regeneration.
EgG1Y162 protein from Echinococcus granulosus modulates the immune functions of mouse splenic lymphocytes and regulates Th9 cells.
PD-L1/PD-1 checkpoint pathway regulates astrocyte morphogenesis and myelination during brain development.
circEFR3A promotes breast cancer progression by sponging miR-590-3p to upregulate androgen receptor expression.
Puerarin Attenuates Osteoarthritis via Multi-Target Regulation of Inflammation, Apoptosis, and ECM Degradation.
The m6A transferase METTL3 regulates high glucose-induced proliferation and apoptosis of human lens epithelial cells through the lncRNA TUG1/KHSRP/p38MAPK signaling axis.
Benserazide‑mediated targeting hexokinase 2 enhances the cytotoxicity of cisplatin in non-small cell lung cancer cell models.
Cuproptosis involvement in neonatal ischemic-hypoxic encephalopathy through the COMMD1/ATP7A signaling axis.
Mito-tempo ameliorates tubular injury of diabetic nephropathy via inhibiting mt-dsRNA release and PKR/eIF2α pathway activation.
Active compounds of licorice ameliorate microplastics-induced intestinal damage by targeting FADD.
Chlorogenic acid counteracts mycophenolate mofetil-induced neurotoxicity in zebrafish and PC12 cells: A potential bioremediation strategy for aquatic pharmaceuticals.
Bioactive ROS-responsive nanotherapeutics attenuate intermittent hypoxia-induced cognitive impairment via NRF2/KEAP1/HO-1 signaling.
Phytochemistry analysis of the above-ground parts of Sanguisorba officinalis L. and its effects on myocardial cell metabolism.
Association of elevated ACSL4 expression with impaired endometrial receptivity in endometriosis and restoration by ACSL4 inhibitor PRGL493.
Optimized synthesis of 5N-D and the exploration of its role as a promising anti-aging agent via AKR1B1 inhibition and PI3K/Akt/Nrf2 regulation.
Design, synthesis and anti-gastric cancer activity of stable Bisamide curcumin analogues.
DDIT4 knockdown suppresses venous malformation progression by inhibiting NF-κB signaling as a potential therapeutic target.
Tectorigenin attenuates myocardial damage by doxorubicin-induced ferroptosis by activating the p62-Keap1-Nrf2/HO-1/GPX4 axis.
Brusatol ameliorates irinotecan-induced delayed diarrhea via inhibition of the cGAS-STING pathway and modulation of intestinal flora.
Shenling Tongqiao powder targets TGF-β1/Smad-Wnt/β-catenin axis to suppress epithelial-mesenchymal transition in chronic rhinosinusitis.
Alpha-Heredin targets CAMKⅡ/DRP1-Mediated mitochondrial fission to trigger ferroptosis in pancreatic ductal adenocarcinoma.
Breviscapine injection and its main component scutellarin prevents lethal enterovirus infection by inhibiting neuroinflammation and oxidative stress in newborn mice.
Dihydrotanshinone I inhibits ovarian tumor growth by suppressing ITGB1/FAK-mediated extracellular matrix signaling.
Rhizoma Panacis Majoris ameliorates rheumatoid arthritis by restoring apoptosis and autophagy dysregulation through reducing HMGB1 expression.
Lactate induces oxidative phosphorylation in osteoblasts via Gpr81-Stat3 signaling.
Identification of ferroptosis-related genes in periodontitis through bioinformatics analysis and experimental validation.
Coactosin-Like Protein Reduces Prostaglandin D(2) Production in Alveolar Macrophages and Alleviates Allergic Airway Inflammation.
Duck plague virus UL13 hijacks an RNA-binding protein, interferon induced protein with tetratricopeptide repeats 5, to promote replication.
Exploring testosterone's impact on pulmonary health in a rat model of COPD: Investigating MMP-9 and FGF-23.
A TP53 Intron-Derived Peptide Promotes Tumor Survival.
Hsp60 lactylation promotes mitochondrial dysfunction and trophoblast apoptosis in preeclampsia.
Study on the role of FN1 in chronic obstructive pulmonary disease.
α-Cyperone safeguards against cerebral ischaemia‒reperfusion injury through the activation of the Nrf2 signalling pathway.
Timosaponin A3 Ameliorates Prostate Cancer Progression via Upregulating STARD4 Mediated Cholesterol Metabolism.
Natural Polyphenol Pentagalloyl Glucose as a Potent Xanthine Oxidase Inhibitor for Hyperuricemia Treatment.
Isoacteoside alleviates LPS-induced depressive-like behaviors in mice by inhibiting neuroinflammation through regulating microglial polarization and oxidative stress.
Yak milk ameliorates chronic alcohol-induced brain injury in mice by modulating the gut microbiota and suppressing the TLR4/NF-κB pathway.
S-ketamine relieves neuropathic pain by inhibiting microglia phagocytosis of the perineuronal nets.
Salecan Suppresses Pancreatic Cancer Progression by Promoting Necroptosis via the RIPK1/MLKL Pathway.
Comparison of Quercetin and Isoquercitrin's Anti-Heart Failure Activity via MAPK Inflammatory Pathway and Caspase Apoptosis Pathway.
Overexpression of alcohol dehydrogenase 1 A inhibits the progress of triple negative breast cancer via Wnt/β-catenin signaling.
Resveratrol Alleviated Oxidative Damage of Bovine Mammary Epithelial Cells via Activating SIRT5-IDH2 Axis.
The synergistic administration of sanguinarine and curcumin ameliorates indomethacin-induced small intestinal injury in rats through the modulation of Nrf2 and NF-κB signaling pathways.
NIR-II Light-Controlled Photosynthetic Activation via an Upconversion Nanoplatform for Targeted Bioenergetic Therapy in Acute Kidney Injury.
An integrated research strategy based on "compound exogenous chemical substances-endogenous metabolites in disease": To explore the scientific basis of Modified Bazhen Yimu Gao in the treatment of primary dysmenorrhea.
Mechanism of xihuang pill inhibition of SLC7A11 deubiquitination through downregulation of the OTUB1 to promote ferroptosis in triple-negative breast cancer.
Ginsenoside Rh2 ameliorates pulmonary fibrosis via HSP70-dependent autophagic flux regulation and senescence arrest.
Danggui Buxue Decoction inhibits pulmonary fibrosis by alleviating TGF-β1-induced proliferation and apoptosis in EBL cells via PI3K/AKT/FOXO1 pathway.
Xuebijing alleviates sepsis-induced acute lung injury by inhibiting alveolar epithelial cell apoptosis via cAMP/PKA signaling pathway.
Integration of network pharmacology and transcriptomics to reveal the mechanism of Paeoniae Radix Alba Polysaccharide in alleviating hepatic fibrosis.
Enzyme kinetic and in silico characterization of cytochrome P450 2E1 inhibition by hydro-ethanolic extract of Entada africana and its protective role in acetaminophen-induced hepatotoxicity.
Protective effect and mechanism of Zhuang medicine Tinosporae Radix on LPS-induced neuroinflammation.
α-lipoic acid attenuates duodenal non-heme iron absorption via microRNA-mediated regulation of divalent metal transporter 1 in iron overloaded rats.
Mechanism of Piezo1 regulating chondrocyte mitochondrial function and promoting fracture healing through β-catenin/LARS2 signaling pathway.
GP2a I118 and GP4 D43 play critical roles in the attachment of PRRSV to the CD163 receptor: implications for anti-PRRSV infection targets.
Inhalation of Mesenchymal-Stem-Cell-Derived Nanovesicles Delivering Catalase Enhances the Treatment for Acute Lung Injury.
YTHDF1-mediated mitochondrial dysfunction and allergic airway inflammation by interaction with β-catenin/TCF4 signaling.
Network pharmacology analysis and experimental validation of EGCG's therapeutic effects against acute lung injury in sepsis.
Elevated ESM1 facilitates peripheral nerve regeneration via enhancing Schwann cell activity and developing a pro-regenerative microenvironment.
Cardiomyocyte pyroptosis inhibited by dental pulp-derived mesenchymal stem cells via the miR-19a-3p/IRF-8/MAPK pathway in ischemia-reperfusion.
BACH1 recruits STAT3 to enhance leukemia inhibitory factor receptor activity and augments the self-renewal capacity of mouse embryonic stem cells.
A novel chronic hepatitis B mouse model with immune activation and liver fibrosis.
FGL2-induced metabolic dysregulation in enteric neural crest cells provides insight into Hirschsprung disease pathogenesis.
Integrative multi-omics analysis decodes HOXC9-driven malignant transformation and metastasis in OSCC.
Novel pH-Responsive PSS-Loaded Chitosan Matrix Nanoparticles Ameliorate Pressure Overload-Induced Cardiac Hypertrophy.
Cu-Mn Bimetallic Mesoporous Silica Nanosonosensitizers Enable Oxeiptosis-Mediated Sonodynamic Therapy for Ultra-Minimally Invasive Treatment of Benign Prostatic Hyperplasia.
Dynamic negative pressure enhances MSC-derived exosomes treatment for vessel injury-related erectile dysfunction by facilitating cavernous diffusion.
Gremlin 1 regulates granulosa cell apoptosis through the TGF-β/SMAD signaling pathway during bovine follicular atresia.
Excessive mitochondrial stress response triggers neuronal injury through the persistent eIF2α phosphorylation in mice exposed to manganese.
Enhanced bioactivity of honeysuckle-Cassia seeds extracts through Lactobacillus acidophilus and Bacillus subtilis co-fermentation: Impact on alcoholic liver disease and gut microbiota.
Region-Specific Metabolic Alterations in the Tryptophan Pathway in Cisplatin-Induced Acute Kidney Injury.
Blue light induces corneal epithelial damage by activating the NLRP3 inflammasome pathway.
Protective effects of total flavonoids of Astragalus membranaceus Bunge combined with selenium-enriched yeast against zearalenone-induced reproductive injury in male mice.
Exploring the potential mechanisms of Jinglinzi powder in treating hepatocellular carcinoma based on LC-MS, network pharmacology, molecular docking, and experimental validation.
Unraveling Laser-Induced peripheral Pain: Proteomic profiling and electrophysiological Dynamics in mice.
The Outer Membrane Protein Tp92 of Treponema pallidum Induces BeWo Cells Apoptosis and Oxidative Stress via the Nrf2/keap1 Pathway.
Novel Indoline Derivatives as Ferroptosis Inhibitors: Synthesis, Biological Evaluation, and Mechanistic Investigation.
Light-Activated CD36-Targeted Cuproptosis Triggers Metabolic-Immune Synergy for Precision Breast Cancer Therapy.
DAZAP2 functions as a pan-coronavirus restriction factor by inhibiting viral entry and genomic replication.
SLC25A40 promotes NSCLC growth by enhancing NADPH-mediated lipid synthesis and suppressing ROS accumulation-induced ferroptosis.
Polyethylene terephthalate (PET) microplastics induced male reproductive toxicity in mice by activating the p38-MAPK pathway.
Gestational zearalenone causes fetal intrauterine growth restriction partially through deriving ROS-Drp1 mediated placental PANoptosis.
YAP/Nrf2 suppresses ferroptosis to alleviate acute lung injury induced by intestinal ischemia/reperfusion.
Arylsulfatase K attenuates airway epithelial cell senescence in COPD by regulating parkin-mediated mitophagy.
MicroRNA-130 as a critical modulator of cardiac remodeling: interplay between autophagic flux and ferroptotic pathways in acute myocardial infarction.
Transplanting neural stem cells overexpressing miRNA-21 can promote neural recovery after cerebral hemorrhage through the SOX2/LIN28-let-7 signaling pathway.
Multilevel Analysis Reveals the Critical Role of Cell Death-Related Molecules and Drugs in Temporomandibular Disorders.
Liver sinusoidal endothelial cells secret C-X-C motif chemokine ligand 10 to promote the recruitment of invariant NKT cells in acetaminophen-induced liver injury.
Neuroprotective Effect of Salvianolic Acid C in Neonatal Rats Following Hypoxic-ischemic Brain Damage.
Knockdown of the CALHM1 Gene Alleviates Allodynia in Rats With Trigeminal Neuralgia.
Magnesium ions attenuate tendon graft fibrosis during its ligamentization after ACL reconstruction through modulation of fibroblast to myofibroblast trans-differentiation by promoting PGE2 secretion.
Baicalin inhibits LPS-induced apoptosis and inflammation in WI- 38 cells by promoting FOXA2/TRIM27 Interaction: Implications for pediatric pneumonia mechanisms.
Diweng Zhixie Power Ameliorates Dampness-Heat Diarrhea by Restoring Intestinal Microbiota Dysbiosis and Short-Chain Fatty Acids.
On-Demand ER Stress Modulation in Tumor Cells and TAMs via an Adaptively Transformable Nanoplatform Enhances Photodynamic Immunotherapy.
Single amino acid substitution at position 614 in SARS-CoV-2 Spike Protein alters viral assembly and infectivity.
Dual-Functional Silicon-Based Nanofluorescent Platform for Iron Detection and Capecitabine Delivery in Colorectal Cancer Treatment.
3D printing-biomimetic local stiff niche enhances glycolysis to boost PDAC cell stem-like phenotype via N6-methyladenosine-suppressed YAP1 mRNA decay.
Role of cellular prion protein in mouse granulosa cells and its effects on ovarian function in knockout mice.
Vitamin C reduces the loss of retinal ganglion cells in chronic glaucoma by inhibiting neuroinflammation.
METTL1 drives glioma progression by promoting N7-methylguanosine (m7G) modification of glycolysis-related enzyme PGK1.
USP32 stabilizes SEMA4C to promote malignant behavior of colon cancer cells.
Magnoflorine ameliorates cartilage degradation in osteoarthritis through inhibition of mitochondrial reactive oxygen species-mediated activation of the NLRP3 inflammasome.
Impact of tertiary lymphoid structure scores and their stage of maturation on prognosis of colorectal cancer patients.
Synergistic anti-tumor effects of mRNA vaccine and PERK inhibitor combination in melanoma treatment.
Increased urea nitrogen salvaging by a remodeled gut microbiota helps nonhibernating pikas maintain protein homeostasis during winter.
Glia maturation factor-β deficiency improves insulin resistance by promoting CARM1-mediated lipid turnover.
Profibrotic impact of PAD4-driven macrophage extracellular traps in ulcerative colitis.
miR-204-5p Mitigates Disc Degeneration via SKI-Mediated Modulation of Apoptotic Signaling and Matrix Remodeling in Nucleus Pulposus.
Echinacoside suppresses macrophage lipid accumulation and attenuates atherosclerosis via the MDM2/PPARγ/ABCA1 signaling axis.
Prunella vulgaris polyphenols alleviate atherosclerosis by regulating lipid metabolism via suppressing STAT3 and activating the PI3K-Akt pathway.
Galangin alleviates vitiligo by targeting ANXA2 degradation in macrophages.
Anti-β2GPI antibodies induce trophoblast pyroptosis and placental inflammation through TLR4/NLRP3/GSDMD axis.
Brusatol suppresses malignant progression of glioma via modulating the miR-574-5p/USP10/PLK1 axis.
Network pharmacology and transcriptomics reveal complanatoside A regulates lipid metabolism in hyperlipidemia and nonalcoholic fatty liver disease via the AMPK pathway.
NSUN2-mediated m5C hypermethylation of hsa_circ_0004516 promotes breast cancer brain metastasis by activating AKT signaling.
Silibinin attenuates 3-nitropropionic acid-induced ovarian toxicity by alleviating oxidative stress and granulosa cell apoptosis.
LARS1 lactylation inhibits autophagy by activating mTORC1 to promote podocytes injury in diabetic kidney disease.
Overexpression of Rap1B alleviate central precocious puberty and neurodevelopmental damage.
PPP1CA promotes hepatocellular carcinoma progression in a YAP1-dependent way.
Wnt/ERK/CDK4/6 activation in the partial EMT state coordinates mammary cancer stemness with self-renewal and inhibition of differentiation.
Activated Peripheral CD8 + T Lymphocytes Inhibit the Proliferation of Hippocampal Neural Stem Cells via the IFN-γ/JAK/STAT Signaling Pathway.
Upadacitinib regulates pain-related pathways and BDNF expression in human monocyte-derived microglial-like cells.
Enhanced Adeno-Associated Virus Production in HEK293 Cells via Dual Inducible Control of Cap and Rep Proteins.
ZDHHC12 Palmitoylates HDAC8 to Promote the Progression of Hepatocellular Carcinoma Associated with a Diet High in Saturated Fatty Acids.
Inhibition of the 4-hydroxynonenal-regulated JNK/c-Jun pathway improves bleomycin-induced lung fibrosis.
Loss of non-canonical translation initiation factors impairs perinatal cardiac function in mice.
The Interventional Effects and Mechanisms of Lonidamine in Combination with Apigenin on Colorectal Cancer.
Soluble MFGE8 mediates cell entry of Crimean-Congo hemorrhagic fever virus.
Fosl2 facilitates chromatin accessibility to determine developmental events during follicular maturation.
cGAS-STING pathway mediates TiO(2) nanoparticle-induced TM4 cell apoptosis via MCUb downregulation and calcium overload.
ATG16L1 controls mammalian vacuolar proton ATPase.
SIRT3 mediates Tubeimoside I's inhibition on pulmonary artery smooth muscle cell proliferation and oxidative stress in pulmonary arterial hypertension.
ZWINT down-regulated by miR-495-3p inhibited lung metastasis of breast cancer by blocking p38 MAPK signaling pathway activation.
ATP citrate lyase (ACLY) promotes the occurrence of gastric cancer through regulating lipid metabolism.
Epigallocatechin gallate improves insulin sensitivity in rats experiencing catch-up growth after being small for gestational age by upregulating PDX1 expression.
Temporally increased 4-sulfated chondroitin sulfate promotes proper progression of bone morphogenetic protein 4-mediated chondrogenic differentiation.
ANK3 Is Regulated by Recursive Splicing and Inhibits Hepatocellular Carcinoma Metastasis by Inhibiting E-Cadherin Protein Degradation.
Lactate-binding protein DNMT3A in HRMECs promotes angiogenesis by upregulating VEGFA through HIF-1α lactylation.
Notoginsenoside R1 attenuates idiopathic pulmonary fibrosis through neuropilin-1/type 2 innate lymphoid cells pathway.
Arginyl-fructosyl-glucose (AFG), a major Maillard reaction product of red ginseng, improved kidney and pancreatic injury in vitro and in vivo in type 2 diabetes mellitus.
RECQL1 as a potential therapeutic target for PARP inhibitor-resistant ovarian cancer.
Chidamide impedes glycolysis but increases ferroptosis and cisplatin sensitivity of lung cancer cells through downregulating USP35.
Synergistic potential of Berberine and Wogonin improved adipose inflammation and insulin resistance associated with obesity through HIF-α axis.
STBD1 mediates the crosstalk between glycogen and lipid droplets in clear cell renal cell carcinoma.
Mycobacterium bovis induces macrophage mitochondrial release of hexokinase 2 to enhance intracellular survival.
The activation of hippocampus microglia in the occurrence of airway hyperresponsiveness comorbidity anxiety.
Villin like suppresses nasopharyngeal carcinoma proliferation by downregulating MYC.
Iron overload-induced ferroptosis in CD8(+) T cells leads to functional abnormalities that promote endometriosis progression.
Neuroprotective Effects and Mechanisms of Arecoline Against H(2)O(2)-Induced Damage in SH-SY5Y Cells.
Steamed Panax notoginseng Saponins Ameliorate Cyclophosphamide-Induced Anemia by Attenuating Gut-Liver Injury and Activating the cAMP/PI3K/AKT Signaling Pathway.
Bioinformatics analysis of IFI6 as a novel prognostic biomarker and its correlation with immune infiltration in breast cancer.
O-GlcNAc transferase influences the progression of degenerative cartilage disease in lumbar facet joint osteoarthritis through FoxO1 and EGR1.
OPA1 modulates NLRP3 inflammasome activation and microglial-mediated neuroinflammation in neonatal hypoxic-ischemic brain injury.
Notch activation downregulates EZH2 to thereby attenuate endothelial cell proliferation and angiogenesis via MYC destabilization.
Whole-transcriptome sequencing analysis of spinal neuronal ferroptosis in aggravating neuropathic pain.
CXCL10 modulates airway inflammation in asthma via Sirt3-dependent macrophage homeostasis.
Structural elucidation of an unusual acid heteropolysaccharide with moieties of glucuronogalactoarabinan and glucuronoarabinogalactan from young shoots of Aralia elata (Miq.) Seem.
Epigenetic regulation by WTAPP1 promotes trophoblast dysfunction in gestational diabetes via CNR1/NF-κB activation.
Functional metabolomics revealed pyroglutamic acid may play a key role in idiopathic pulmonary fibrosis.
Tssk6 is essential for the regulation of male zebrafish fertility.
Histone H3 lysine 18 lactylation attenuates neuroinflammation and neurological damage by regulating microglial plxnb2 after ischemic stroke.
Oxyberberine alleviates fructose-induced hyperuricemia by modulating purine metabolism and gut microbiota.
Aβ-damaged neural stem cells migration and differentiation through Wnt3a/β-catenin pathway: Protective effects of 17β-E2.
miR-423-3p inhibits CTNNBIP1/WNT preventing hyperandrogenic polycystic ovary syndrome†.
RAPGEF6 is a key biomarker with temporal characteristics in sepsis and exacerbates inflammation and oxidative stress by NF-κB-mediated necroptosis.
Betulinic acid protects against LPS-induced intestinal inflammatory damage via inhibiting Nrf2/TXNIP/NLRP3 signaling pathways in mice.
Research on the Protective Effects and Mechanisms of Gallic Acid Against Cognitive Impairment Induced by Chronic Sleep Deprivation.
Preventive and Therapeutic Effects of Hydrogen-Generating Si-Based Agent on Pressure Ulcers in Mice.
Lipin3 deficiency promotes hepatocyte ferroptosis and pyroptosis via activating JAK1-STAT3 pathway during acetaminophen induced acute liver injury.
EDC4 enhances multi-drug chemosensitivity in pancreatic cancer via GR50-based profiling.
NEK7 mediates ESRD-associated endothelial injury by activating the NLRP3 inflammasome.
Andrographolide attenuates oxidative stress and apoptosis in osteoporosis rats via MEK/ERK and Beclin-1/ATG-5-mediated autophagy pathway.
A hydrogel tissue adhesive incorporating basic fibroblast growth factor-loaded liposomes accelerates cutaneous wound healing by enhancing cell proliferation, collagen synthesis and angiogenesis.
A Phototherapy Nanosensitizer-Unlocked Multihit Strategy to Inhibit Tumor Stemness and Potentiate Sorafenib Response in Hepatocellular Carcinoma.
Bioinspired Multifunctional Hydrogel Loaded with Netrin-1 for Diabetic Wound Healing.
Rutin Enhances Intestinal Barrier Function and Protects Against X-Ray Radiation-Induced Barrier Dysfunction in Human Epithelial Caco-2 Cells.
FAM111B enhances glycolysis and promotes metastasis of prostate cancer by upregulating LDHA.
SELENBP1 protects against kidney fibrosis in chronic kidney disease as a methanethiol oxidase.
Generation of Ext1 Gene-Edited Mice Model Via Dual sgRNAs/Cas9 System and Phenotypic Analyses.
SP1-Mediated upregulation of CLEC18B promotes the proliferation and metastasis of glioma through regulation of the Wnt/β-Catenin/EMT Pathway.
Gut microbiome contributes to 6PPD-quinone induced cognitive impairment through PI3K/Akt signaling.
Lactate Prevents Glucose Deprivation-Induced Parthanatos in Gastric Cancer Cells Through Alleviating Intracellular Reactive Oxygen Species.
Low Wall Shear Stress Promotes Atheroma via Arterial Iron Accumulation.
Preprotective Effects of Cardamomin From Amomum villosum Lour. on H(2)O(2) -Induced Oxidative Damage In Vitro and Cerebral Ischemic Stroke In Vivo.
Icariside II Ameliorates Depression Induced by High-Fat Diet via the Microbiota-Gut-Brain Axis in Mice.
PSAT1 knockdown mediated VDAC1 oligomerization promotes ferroptosis and suppresses cell proliferation in esophageal squamous cell carcinoma.
The β-glucan from Lentinus alleviates UVB-induced dermal fibroblasts senescence and skin photoaging.
Fingolimod Exerts Therapeutic Effects on Autistic Mice via Improving the Structure and Function of Meningeal Lymphatics.
FXR suppress Müller cell activation by regulating cGAS/STING pathway in diabetic retinopathy.
Ginsenoside Compound K Inhibits Wnt/β-Catenin Signaling and Anti-Angiogenesis, Alleviating Joint Injury in Rats With Adjuvant Arthritis.
The integrated treatment of photodynamic therapy and oncolytic Virotherapy: A dual-modal paradigm for breast Cancer.
MTHFD2 drives retinoblastoma progression via Notch signaling activation: Implications for targeted pediatric ocular cancer therapy.
Very high-dose vitamin D₃ supplementation reduces the expression of genes and proteins engaged in β-oxidation in healthy pigs.
TBRG4 regulates ubiquitination of Beclin1 and participates in autophagy pathway to inhibit intervertebral disc degeneration.
Astragalin induces immunogenic cell death in liver cancer by targeting NQO2 to promote ROS-mediated endoplasmic reticulum stress pathway.
Treadmill exercise alleviates STING-mediated microglia pyroptosis and polarization via activating mitophagy post-TBI.
Role of IL33/HIF1α/VEGF in intermittent hypoxia-induced lung injury.
Study on the Specifications of Scutellariae Radix in Da-Chai-Hu-Tang Based on Efficacy in a Rat Model of Large Intestine Damp-Heat Syndrome and Chemical Composition Differences.
Collagen peptides from Skipjack tuna (Katsuwonus pelamis) bones: Composition, characterization, and mechanism of high-fat diet-induced NAFLD amelioration.
BMAL1 modulates respiratory syncytial virus-induced inflammation through p38 mitogen-activated protein kinase pathway: insights into circadian regulation.
Subacute exposure to thallium disrupts renal energy metabolism by impairing the function of subcellular organelles in aged mice of both sexes.
Elafin inhibits macrophage activation by blocking a chloride channel.
Mechanism and marker of voriconazole-induced liver injury: insights from a quantitative systems toxicology approach.
Protective Effect of Vinegar Powder on (60)Coγ Radiation-Injured Mice and Its Potential Mechanism.
ZC3H13 facilitates the progression of acute myeloid leukemia through m6A-FOXP1-mediated metabolic reprogramming.
High glucose induces hippocampal neuron impairment through the SKP1/COX7C pathway: A potential mechanism for perimenopausal depression.
Mechanistic insights into baicalein's anti-inflammatory effects in COPD: Targeting oxidative stress and CD8⁺ T cell cytotoxicity.
The total xanthones from Gentianella acuta alleviate acute myocardial infarction by targeting BRD4-mediated cardiomyocyte pyroptosis and inflammation.
PDCD4 exacerbates myocardial ischemia-reperfusion injury via AKT-mediated apoptosis.
Regulation of melanogenesis via ubiquitin-proteasome system and autophagy by 3,3,5-trimethylcyclohexyl succinate dimethylamide and tranexamic acid.
RPS27L Enhances Myogenesis and Muscle Mass by Targeting IGF1 Through Liquid-Liquid Phase Separation.
APOL2 Stabilizes Ku80 to Confer NHEJ-Mediated Radioresistance in Gastric Cancer.
FOXQ1 Regulates Brain Endothelial Mitochondrial Function by Orchestrating Calcium Signaling and Cristae Morphology.
Microwave-Activated Bacterial Biorobot for Multimodal Cancer Therapy.
The duck plague virus UL7 protein mediates RIG-I degradation to block host antiviral responses and promote viral pathogenesis.
Hydrogen activated the Nrf2/HO pathway to alleviate the cognitive decline in PD Drosophila after long-term sevoflurane exposure.
Metabolic syndrome-related gene signature for prognosis and immune microenvironment prediction in hepatocellular carcinoma.
Leucine Attenuates Osteoarthritis via mTORC1/LXRα-Mediated Macrophage Reprogramming and Rspo2/β-Catenin Axis Suppression.
Discovery of novel covalent PI3Kδ inhibitors bearing alaninamide moiety by lysine-targeted covalent strategy.
Lactobacillus reuteri attenuates methotrexate-induced liver injury via modulation of oxidative stress and inflammation through HO-1/GPX4 and NF-κB/NLRP3 pathways.
Icariside II ameliorates slow transit constipation by inhibiting macrophage polarization and suppressing the cGAS-STING pathway.
DDX1 facilitates lenvatinib resistance in hepatocellular carcinoma through regulating ephrin-A3 and activating the Wnt/β-catenin signaling pathway.
The relationship between high serum UA levels and decidualization and angiogenesis in endometrium.
TP53-dependent antitumor effects of DHODH Inhibition in nasopharyngeal carcinoma.
Lipidomic and transcriptomic analysis and its therapeutic implications in Chinese Kazakh patients with esophageal squamous cell carcinoma.
Dapagliflozin ameliorates high glucose-induced peritoneal fibrosis through downregulation of ENKUR/PI3K/AKT signaling pathway.
Parthenolide Exerts Protection against Hypoxic-Ischemic Brain Damage in Neonatal Rats by Inhibiting Perk-Mediated Endoplasmic Reticulum Stress.
Integrating Functional Genomic Screens and Multi-Omics Data to Construct a Prognostic Model for Lung Adenocarcinoma and Validating SPC25.
SKP2 protein as a prognostic biomarker for glioma and promotes tumor progression by regulating the cell cycle.
5-HEPE Ameliorates Aging of Duck Ovarian Granulosa Cells by Targeting FOXM1 and Suppressing Oxidative Stress.
CaMKII Drives Synaptic Maturation by Coordinating Spine Remodeling and Receptor Segregation via Liquid-Liquid Phase Separation.
Hsa-miR-423-5p selectively loaded in hypoxic exosomes reduces the sensitivity of normoxic hepatocellular carcinoma to sorafenib via autophagy.
Evolutionary dampening of Wnt signaling may contribute to naturally ascrotal testes in mammals: Dampened Wnt pathway under ascrotal testes.
Sagittaria Sagittifolia Polysaccharide Ameliorates Diabetic Retinopathy in Mice via Inhibiting TLR4-Mediated Microglial Activation.
Enoxaparin alleviates preeclampsia by enhancing trophoblast function via the NSUN2-mediated m(5)C methylation of PAX3 mRNA.
Lineage plasticity and signal dysregulation define the cellular trajectory of osteoarthritis progression.
Identification of a Treg-related gene signature for predicting prognosis and immunosuppression in skin cutaneous melanoma.
Deferoxamine improves femoral trochlear dysplasia following patellar dislocation through HIF-1α/VEGF-mediated angiogenesis-osteogenesis coupling.
Kaempferol attenuated LPS-induced microglial neurotoxicity by promoting mitophagy to inhibit mtDNA-mediated NLRP3 inflammasome activation.
Pulchinenoside E2: A dual-functional STAT3 and autophagy inhibitor with potent anti-metastatic activity in triple-negative breast cancer.
Syringin attenuates Alzheimer's disease-associated neuroinflammation by inhibiting NLRP3 inflammasome activation.
Kang Shuai Lao Pian exerts anti-aging effects by enhancing mitochondrial oxidative metabolism.
Combined transcriptomics and network pharmacology to elucidate the mechanisms of rutin in treating ischemic stroke rat.
Germacrone Ameliorates Diabetic Kidney Disease by Activating TFEB to Promote Autophagy and Inhibit Inflammation.
MiR-503-5p mediates cell cycle arrest and fibrosis of peritoneal mesothelial cells with a high peritoneal solute transport status.
Quercetin's regulation of glucose and lipid metabolism in gestational diabetes mellitus: role of the PCSK9/LDLR axis.
Exploring targeted therapies against RFPL3 for non-small cell lung cancer with lymph node metastasis.
Vasostatin-2 attenuates injury-induced neointimal hyperplasia through the ACE2/MasR/PPARγ/NR1D1/Gas1 axis.
Autism-Associated Gut Microbiota-Derived Enterococcus facium Modulates Gut-Brain Axis Function and Behavior in Mice.
IGFBP7 and CCT2 are novel lactylation-driven mediators of endothelial-to-mesenchymal transition in idiopathic pulmonary fibrosis.
Oligoclonal tumor-specific CD8 T-cell revival and IRE1α/XBP1-GDF15-mediated immunosuppressive niches determine neoadjuvant chemoimmunotherapy efficacy in cervical cancer.
Resveratrol-Supported Bioenergetics Leads to Higher Productivity and Accompanying Endoplasmic Reticulum Stress in a mAb-Producing CHO Cell Line.
Up-regulation of Ifi27l2a expression in bone marrow monocytes contributes to glucocorticoid-induced bone loss.
Circ_0000756 Mediates Oxidative Stress and Metabolic Memory in Diabetic Neuropathy via miR-7b Suppression of NRF2/ARE Pathway.
Umbilical Cord Mesenchymal Stromal Cell-Derived Extracellular Vesicles Transfer CD59 to Astrocytes to Alleviate Complement-Dependent Cytotoxicity.
Empagliflozin alleviates hepatic ischemia-reperfusion injury by inhibiting c-Myc through the JAK1-STAT3 signaling pathway.
RNF180 suppressed aggressiveness by degrading NOTCH1, TRIM24 and FOXC1, and chemoresistance by degrading ACC1 and ACLY in colorectal cancer.
Dual-Targeted Biomimetic Nanoparticles for Enhanced Delivery of Polyphyllin B Synergistically Induce Ferroptosis and Immunogenic Cell Death in Gastric Cancer.
Unravelling butyrate metabolism in sepsis: identification of key genes.
Sex-Specific Involvement of Gut Microbiota in Behavioral and Endocrine Responses to Chronic Predator Odor in Brandt's Voles.
CARMN loss promotes VSMC-derived foam cell formation and atherosclerosis through transcriptional downregulation of autophagy.
Application of Dental Pulp Stem Cell-Derived Intracellular Vesicles for Diabetic Wound Healing.
Oocyte-specific Ahr deletion disrupts folliculogenesis and female fertility in mice.
Formoterol, a clinically approved drug, inhibits ferroptosis by suppressing lipid peroxidation and attenuates APAP-induced acute liver injury.
Paraquat induced neuro-immunotoxicity: Dysregulated microglial antigen processing and mitochondrial activated mechanisms.
Gut flora-derived succinate exacerbates Allergic Airway Inflammation by promoting protein succinylation.
Molecular biomarkers for the prognosis of breast cancer: role of amino acid metabolism genes.
Quercetin Induces Apoptosis Through Downregulating P4HA2 and Inhibiting the PI3K/Akt/mTOR Axis in Hepatocellular Carcinoma Cells: An In Vitro Study.
Insight of action mechanism of Astragaloside IV for relieving of cerebral ischemic injury in a rat model of middle cerebral artery occlusion reperfusion via proteomics and network pharmacology.
Exogenous α-Synuclein Induces Oxidative Damage to Dopaminergic Neurons Through p-NMDAR2B/Nur77.
Next-generation sequencing in early-stage multiple primary lung cancer: The prognostic significance of genomic accumulation status and BCL2L11(del).
m6A-induced DEAD-box RNA helicase 21 enhances lipid metabolism via 3‑hydroxy-3-methylglutaryl-CoA synthases 1 in colorectal cancer.
Dihydroartemisinin ameliorates hemarthrosis-induced cartilage degeneration by suppressing chondrocyte senescence via activation of Keap1-Nrf2 signaling pathway.
Ferulic acid protects against stress-induced myocardial injury in mice.
Sulfasalazine improves neuronal function in mice with ischemic stroke by inhibiting the STING/NF-κB pathway.
Daidzein Attenuates Cadmium-Induced Neurotoxicity via Inhibiting Apoptosis and Mitophagy in the Cerebral Cortex of Sprague-Dawley Rats.
Macelignan Improves Functional Recovery After Spinal Cord Injury by Augmenting Autophagy via the AKT-mTOR-TFEB Signaling Pathway.
HBCOC attenuates cerebral ischemia-reperfusion injury in mice by inhibiting the inflammatory response and autophagy via TREM-1/ERK/NF-κB.
NAE1 protein: a prognostic, immunomodulatory, and therapeutic biomarker associated with neddylation in hepatocellular carcinoma.
Protective effects of jiawei yupingfeng polysaccharides on cyclophosphamide-induced intestinal injury in mice.
Poly-IC Alleviates Nitroglycerin-Induced Migraine by Inhibiting Neuroinflammation via TLR3/TRIF Signaling Pathway.
miR-278-3p targets ATG16L1 to modulate autophagy and suppresses CLas proliferation in Diaphorina citri.
Genome-wide identification of glutathione S-transferase (GST) gene family and its regulating characteristics responding to sperm capacitation in Eriocheir sinensis.
A novel 5-differentially expressed gene (DEG) signature predicting the prognosis in patients with metastatic liver malignancies and the prognostic and therapeutic potential of SPP1.
RNA binding motif protein 25 is a negative prognostic biomarker and promotes cell proliferation via alternative splicing in hepatocellular carcinoma.
METTL3 enhances esophageal squamous cell carcinoma progression by suppressing ferroptosis through the PBX3/CA9 cascade.
Novel progressive rod-cone degeneration mutation causes retinitis pigmentosa.
Empagliflozin attenuates renal damage in diabetic nephropathy by modulating mitochondrial quality control via Prdx3-PINK1 pathway.
Adipose stem cells ameliorate erectile dysfunction in diabetes mellitus rats by attenuating ferroptosis through NRP1 with SLC7A11 interaction.
EPIC-1042 alleviates cerebral ischemic/reperfusion injury through TAX1BP1-induced mitophagy.
Unveiling the Role of Oligosaccharyltransferase STT3B in Colorectal Cancer Tissues: Clinical significance and Molecular Mechanisms Driving the Formation of Tertiary Lymphoid Structures.
Breaking the synergism of iron overload and miR-122 to rescue lipid accumulation and peroxidation in MASLD.
The ER protein CANX (calnexin)-mediated autophagy protects against alzheimer disease.
The ROS Mediates MCUb in Mitochondria-Regulated Apoptosis of TM4 Cells Induced by Titanium Dioxide Nanoparticles.
METTL7B-induced histone lactylation prevents heart failure by ameliorating cardiac remodelling.
Hydrogen sulfide improves depression-like behaviors in CUMS-induced mice by regulating autophagy.
Experimental Autoimmune Neuritis Nerve Demyelination Is Attenuated by Blocking JAK2/STAT3 Signaling Pathway in Rats.
Liquiritin improves macrophage degradation of engulfed tumour cells by promoting the formation of phagolysosomes via NOX2/gp91phox.
Effective-compounds of Jinshui Huanxian Formula acts as an SRC inhibitor to inhibit HK2-mediated H3K18 lactation and improve pulmonary fibrosis.
Deoxyshikonin from Arnebiae Radix promotes hair growth by targeting the Wnt/β-catenin signaling pathway.
Apigenin ameliorates inflamed ulcerative colitis by regulating mast cell degranulation via the PAMP-MRGPRX2 feedback loop.
Procyanidins inhibit alphacoronavirus infection by reducing interferon antagonism.
10-Hydroxydec-2-enoic acid reduces vascular smooth muscle cell inflammation via interacting with Toll-like receptor 4.
GRB2 Promotes Malignant Behaviors of Breast Cancer by Modulating the Global Expression and Alternative Splicing Profiles in SK-BR-3 Cells Through Binding mRNA.
The Immune Regulation of Melanin From Gallus gallus domesticus Brisson Against Cyclophosphamide-Induced Immunosuppression.
Trehalose attenuates testicular aging by activating autophagy and improving mitochondrial quality.
EHF promotes liver cancer progression by meditating IL-6 secretion through transcription regulation of KDM2B in TAMs.
Dectin-1 participates in neuroinflammation and dopaminergic neurodegeneration through synergistic signaling crosstalk with TLR4.
IFITM2 Modulates Endocytosis Maintaining Neural Stem Cells in Developing Neocortex.
Enhancing Prime Editing Efficiency Through Modulation of Methylation on the Newly Synthesized DNA Strand and Prolonged Expression.
Mitigating Doxorubicin-Induced Cardiotoxicity and Enhancing Anti-Tumor Efficacy with a Metformin-Integrated Self-Assembled Nanomedicine.
MARVELD1 inhibits Neuro2a cell migration and tumorigenesis via regulating the transcriptional coactivators and protein methylation.
Aged mice-derived bronchial epithelial cells regulate Th17 cell differentiation in asthma via the MBD2-sICOSL axis.
Subchondral injection of human umbilical cord mesenchymal stem cells ameliorates knee osteoarthritis by inhibiting osteoblast apoptosis and TGF-beta activity.
Mechanistic Insights into the Anti-Hepatocellular Carcinoma Effects of ACY-1215: p53 Acetylation and Ubiquitination Regulation.
Metabolic-associated fatty liver disease (MAFLD) promotes the progression of hepatocellular carcinoma by enhancing KIF20A expression.
GTS-21 alleviates sepsis-induced atrial fibrillation susceptibility by modulating macrophage polarization and Neuregulin-1 secretion.
Immunodynamic axis of fibroblast-driven neutrophil infiltration in acute pancreatitis: NF-κB-HIF-1α-CXCL1.
Pterostilbene attenuates intestinal barrier damage and secondary liver oxidative stress in a murine model of Clostridium difficile infection by regulating the gut microbiota.
Prostaglandin E2 receptor EP4 activation induces tolerogenic dendritic cells to mitigate ischemic acute kidney injury.
RBAP48 facilitates the oral squamous cell carcinoma process in an androgen receptor-dependent and independent manners.
Neutrophil Extracellular Traps Promote AIM2-Dependent Microglial Pyroptosis Following Stroke.
Single-cell and spatial transcriptome analyses reveal tumor heterogeneity and immune remodeling involved in pituitary neuroendocrine tumor progression.
Obacunone acts as a histone deacetylase 1 inhibitor to limit p38MAPK signaling and alleviate osteoarthritis progression.
AMH regulates granulosa cell function via ESR2/ p38-MAPK signaling pathway in sheep.
Multi-omics analyses, cell experiments, and network pharmacology tools identified key proteins and candidate drugs for alopecia areata treatment.
Metabolites from the Dendrobium Endophyte Pseudomonas protegens CM-YJ44 Alleviate Insulin Resistance in HepG2 Cells via the IRS1/PI3K/Akt/GSK3β/GLUT4 Pathway.
Enhanced SIRT1-TFEB Interaction Promotes Lysosome Biogenesis and Autophagy by Reducing TFEB Acetylation: Revealing the Enterotoxicity Disparity of Deoxynivalenol and T-2 Toxin.
Atractylenolide-1 Alleviates Ulcerative Colitis via Restraining RhoA/ROCK/MLC Pathway-Mediated Intestinal Barrier Dysfunction.
Ethanol extract of Moschus attenuates glutamate-induced cytotoxicity in HT22 cells by regulating the Nrf2 and MAPK pathways.
Huatanhuoxue decoction alleviates airway inflammation by regulating IL-17A signaling pathway in obese asthmatic mice.
TiO(2) Nanotube Implants Modified with Silk Fibroin and Mesoporous Silica Nanocomposite Coatings Enable Efficient Drug Release to Promote Osteogenesis.
IGFBP5 promotes EndoMT and renal fibrosis through H3K18 lactylation in diabetic nephropathy.
Icariin alleviates cardiomyocyte pyroptosis through AMPK-NLRP3 pathway to ameliorates diabetic cardiomyopathy.
Inhibition of CDK5 signaling mediated inflammation in macrophages promotes cutaneous wound healing.
Long non-coding RNA HOXA11-AS inhibits apoptosis, induces proliferation, and promotes autophagy via the miR-214-3p/ATG12 axis in acute T lymphoblastic leukemia.
Comprehensive analysis of FAM83B in pan-cancer and preliminary exploration in esophageal squamous cell carcinoma.
Carboxylesterase 1 regulates peroxisome proliferator-activated receptor gamma to inhibit the growth and metastasis of breast cancer cells.
Macrophage Notch1 drives septic cardiac dysfunction by impairing mitophagy and promoting NLRP3 activation.
Identification and validation of USP15 and CUL2 as ubiquitination related biomarker in chronic obstructive pulmonary disease.
MiR-493-5p functions as a tumour suppressor in head and neck squamous cell carcinoma progression by targeting HIF-1α.
Metformin ameliorates trophoblastic immunometabolic disorders via attenuating TLR4/NF-κB signaling through ATXN7L3-mediated histone H2B monoubiquitination.
Mechanical signal modulates prostate cancer immune escape by USP8-mediated ubiquitination-dependent degradation of PD-L1 and MHC-1.
Controlled reversible methionine-selective sulfimidation of peptides.
Immunopeptidomics-guided discovery and characterization of neoantigens for personalized cancer immunotherapy.
Structural Optimization of Pyrazole Compounds as Hsp90 Regulators with Enhanced Antitumor Activity.
Repetitive Compressive Loading Downregulates Mitochondria Function and Upregulates the Cartilage Matrix Degrading Enzyme MMP-13 Through the Coactivation of NAD-Dependent Sirtuin 1 and Runx2 in Osteoarthritic Chondrocytes.
Osteocyte-derived extracellular vesicles mediate the bone-to-cartilage crosstalk and promote osteoarthritis progression.
Single-cell sequencing and transcriptomic data reveal that P65 activation significantly promotes microglia-mediated neuroinflammation after ischemic stroke.
Co-encapsulation of norcantharidin prodrugs and lomitapide in nanoparticles to regulate CCL4 expression by inhibiting Wnt/β-catenin pathway for improved anti-tumor immunotherapy.
Iron Replacement Attenuates Hypoxic Pulmonary Hypertension by Remodeling Energy Metabolism via Regulating the HIF2α/Mitochondrial Complex I, III/ROS Axis.
miR-139-5p activates ferroptosis by inhibiting the expression of HMG-CoA reductase to inhibit the progression of glioma.
A dual-targeting bio-liposomes nanodrug repair endothelial cell dysfunction and restore macrophage cholesterol flow homeostasis to treat early atherosclerosis.
LONP1 facilitates pulmonary artery smooth muscle cell glycolytic reprogramming by degrading MPC1 in pulmonary hypertension.
SIRT2 inhibition enhances mitochondrial apoptosis in Brucella-infected bovine placental trophoblast cells.
USP14 inhibits mitophagy and promotes tumorigenesis and chemosensitivity through deubiquitinating BAG4 in microsatellite instability-high colorectal cancer.
Retroviral foamy virus gag induces parkin-dependent mitophagy.
DNA dioxygenase TET2 deficiency aggravates sepsis-induced acute lung injury by targeting ITGA10 via the PI3K/AKT signaling pathway.
Identification and verification of a polyamine metabolism-related gene signature for predicting prognosis and immune infiltration in osteosarcoma.
Gut microbial conversion of dietary elderberry extract to hydrocinnamic acid improves obesity-associated metabolic disorders.
Tong-Qiao-Huo-Xue Decoction mitigates post-stroke inflammatory response via suppression of the FIB-NLRP3 signaling pathway.
ClC-3-depedent polarization of microglia protects against cerebral ischemic injury in mice.
Inhibition of diacylglycerol O-acyltransferase 1 provides neuroprotection by inhibiting ferroptosis in ischemic stroke.
Comprehensive bioinformatics analysis of MEX3 family genes in hepatocellular carcinoma.
miR-370-3p Inhibited the Proliferation of Sheep Dermal Papilla Cells by Inhibiting the Expression of SMAD4.
Network pharmacology and experimental verification to explore the molecular mechanisms of Astragaloside IV against diabetic encephalopathy.
Copper's new role in cancer: how cuproptosis-related genes could revolutionize glioma treatment.
A Novel Hybrid Peptide VLP-Aβ Exhibits Antioxidant Activity In Vitro and In Vivo via KEAP1-NRF2-ARE Signaling Pathway.
Multiomics analysis revealed the effects of polystyrene nanoplastics at different environmentally relevant concentrations on intestinal homeostasis.
SNORD9 promotes ovarian cancer tumorigenesis via METTL3/IGF2BP2-mediated NFYA m6A modification and is a potential target for antisense oligonucleotide therapy.
Inhibition of microRNA-139-5p by glucagon-like peptide-1 ameliorates oxidative stress-induced vascular endothelial cell damage via targeting SOD1/GCLc.
SIRT1 Alleviates Mitochondrial Fission and Necroptosis in Cerebral Ischemia/Reperfusion Injury via SIRT1-RIP1 Signaling Pathway.
FABP3 promotes cell apoptosis and oxidative stress by regulating ferroptosis in lens epithelial cells.
Curcumin attenuates myocardial ischemia‑reperfusion‑induced autophagy‑dependent ferroptosis via Sirt1/AKT/FoxO3a signaling.
Cellular heterogeneity and communication networks in gastric cancer: Single-cell analysis reveals β-hydroxybutyrylation-associated genes and immune infiltration characteristics.
Inhibition of the cGAS‑STING Pathway Reduces Cisplatin-Induced Inner Ear Hair Cell Damage.
Exploring the Role of Gut Vascular Barrier Proteins in HIV-Induced Mucosal Damage: A Comparative Study.
Astragaloside IV Relieves Central Sensitization by Regulating Astrocytic ROS/NF-κB Nuclear Translocation Signaling in Chronic Migraine Male Rats.
Aloe-Emodin Improves Mitophagy in Alzheimer's Disease via Activating the AMPK/PGC-1α/SIRT3 Signaling Pathway.
DNLA Delayed the Appearance of Learning and Memory Impairment of APP/PS1 Mice: Involvement of mTOR/TFEB/v-ATPase Signaling Pathway.
NGR1 reduces neuronal apoptosis through regulation of ITGA11 following subarachnoid hemorrhage.
SIRT5 desuccinylating IDH2 to alleviate oxidative stress in bovine mammary epithelial cells induced by ammonia.
A glucomannan from defatted Ganoderma lucidum spores: structural characterization and immunomodulatory activity via activating TLR4/MyD88/NF-κB signaling pathway.
Adiponectin facilitates the cell cycle, inhibits cell apoptosis and induces temozolomide resistance in glioblastoma via the Akt/mTOR pathway.
Exercise Training After Myocardial Infarction Enhances Endothelial Progenitor Cells Function via NRG-1 Signaling.
Anti-inflammatory Fatty Acid Derivatives From Mangrove-derived Actinomycetes Streptomyces sp.
Metformin delays the decline in thermogenic function of brown adipose tissue in a mouse model of Hutchinson-Gilford progeria syndrome.
SERCA2 dysfunction accelerates angiotensin II-induced aortic aneurysm and atherosclerosis by induction of oxidative stress in aortic smooth muscle cells.
The Effects of different forms of exercise during the early life on the bone microstructure of ovariectomized mice.
GPSM1 interacts and cooperates with MMP19 to promote proliferation and EMT in colorectal cancer cells.
Early intervention with pericyte Fli-1 post-TBI attenuates hippocampal BBB disruption and subsequent neuroinflammation with neurological deficits.
1-benzyl-6-nitro-4-phenyl-4-(methoxycarbonyl)-2(1H)-pyridinone, a novel pirfenidone derivative, alleviate hepatic fibrosis through T cells.
Vagus nerve stimulation inhibits PANoptosis and promotes neurofunctional recovery of cerebral ischemic stroke in a Sirt1-dependent manner.
Concoctive principles of detoxification and retention of the main toxicity of Tripterygium wilfordii and its anti-inflammatory efficacy by concocting with the medicinal excipient Spatholobi Caulis juice.
Zhuyu pill attenuates metabolic-associated fatty liver disease by regulating macrophage polarization through TLR4 signaling pathway.
Targeting the NF-κB p65-MMP28 axis: Wogonoside as a novel therapeutic agent for attenuating podocyte injury in diabetic nephropathy.
ANXA2 promotes chondrocyte differentiation and fracture healing by regulating the phosphorylation of STAT3 and PI3K/AKT signaling pathways.
Disulfiram/Cu targeting FOXO6 modulates sensitivity of hepatocellular carcinoma to lenvatinib via disrupt choline metabolic.
FABP4 Mediates Inflammation to Regulate Endometrial Epithelial Cell Function During Early Gestation in Sheep.
Antagonizing Il10 and Il4 signaling via intracerebral decoy receptor expression attenuates Aβ accumulation.
The RNA-binding protein LARP6 regulates the alternative splicing of related genes in MDA-MB-231 cells.
Reticulophagy promotes EMT-induced fibrosis in offspring's lung tissue after maternal exposure to carbon black nanoparticles during gestation by a m(5)C-dependent manner.
TRAF1 promotes osteoclastogenesis by enhancing metabolic adaptation to oxidative phosphorylation in an AKT-dependent manner.
CD47 Contributes to the Proliferation of Breast Cancer.
Dual GLP-1 and GIP Agonist Tirzepatide Exerted Neuroprotective Action in a Parkinson's Disease Rat Model.
Inhibition of NLRP3 alleviates calcium oxalate crystal-induced renal fibrosis and crystal adhesion.
VHL ameliorates arecoline-induced oral submucosal fibrosis by promoting HDAC6 ubiquitination and blocking NF-κB pathway.
Human Cytomegalovirus Infection Reduces an Endogenous Antiviral Fatty Acid by Promoting Host Metabolism.
Klotho alleviates oxidative stress and mitochondrial dysfunction through the Nrf2/HO-1 pathway, thereby reducing renal senescence induced by calcium oxalate crystals.
Yinchenhao decoction alleviates obstructive jaundice liver injury by modulating epidermal growth factor receptor and constitutive androstane receptor signaling.
The Frmpd3 Protein Regulates Susceptibility to Epilepsy by Combining with GRIP and GluA2.
Reprogramming Macrophage Phenotype Using a Reactive Oxygen Species-Responsive Liposome Delivery System for Inflammation Microenvironment Remodeling and Osteoarthritis Treatment.
Apabetalone alleviates ligature-induced periodontitis by inhibiting M1 macrophage polarization via an immunometabolic shift.
Umbelliferone attenuates calcium oxalate crystal-induced renal injury and inflammation by attenuating autophagy through the PI3K/AKT pathway.
Circ_RUSC2 Sequesters miR-661 and Elevates TUSC2 Expression to Suppress Colorectal Cancer Progression.
Protective Effects of a Polyherbal Mixture on Intestinal Injury via the NF-κB Signaling Pathway and Gut Microbiota Modulation in Hyperuricemic Mice.
ZDHHC9-mediated CD38 palmitoylation stabilizes CD38 expression and promotes pancreatic cancer growth.
Deletion of ENO1 sensitizes pancreatic cancer cells to gemcitabine via MYC/RRM1-mediated glycolysis.
Seminal plasma proteomics of asymptomatic COVID-19 patients reveals disruption of male reproductive function.
miRNA let-7f-5p-encapsulated labial gland MSC-derived EVs ameliorate experimental Sjögren's syndrome by suppressing Th17 cells via targeting RORC/IL-17A signaling axis.
IFI16 recruits HDAC1 and HDAC2 to deacetylate the Kaposi's sarcoma-associated herpesvirus (KSHV) latency-associated nuclear antigen (LANA), facilitating latency.
MiR-222-3p loaded stem cell nanovesicles repair myocardial ischemia damage via inhibiting mitochondrial oxidative stress.
A New Human SCARB2 Knock-In Mouse Model for Studying Coxsackievirus A16 and Its Neurotoxicity.
Oleanolic Acid Alleviates Hyperuricemia via Gut Microbiota Control the Integrity of Gut Barrier and the Expressions of Urate Transporter in Mice.
Microneedles Loaded with Nitric-Oxide Driven Nanomotors Improve Force-Induced Efferocytosis Impairment and Sterile Inflammation by Revitalizing Macrophage Energy Metabolism.
Platelet hitchhiking vascular-disrupting agents for self-amplified tumor-targeting therapy.
Correlation of IGF2 levels with sperm quality, inflammation, and DNA damage in infertile patients.
Intranasal oxytocin alleviates postsurgical pain and comorbid anxiety in mice: Participation of BK(Ca) channels in the hippocampus.
Bronchopulmonary dysplasia demonstrates dysregulated autotaxin/lysophosphatidic acid signaling in a neonatal mouse model.
Topical transdermal administration of lenalidomide nanosuspensions-based hydrogels against melanoma: In vitro and in vivo studies.
Gastrodin Alleviates Lumbar Intervertebral Disc Degeneration by Suppressing the NF-κB and MAPK Pathways.
USP5 Stabilizes IKBKG Through Deubiquitination to Suppress Ferroptosis and Promote Growth in Non-small Cell Lung Cancer.
GLA deficiency causes cardiac hypertrophy via enhanced autophagy.
Inhibition Peroxiredoxin-2 by Capsaicin Ameliorates Rheumatoid Arthritis via ROS-Mediated Apoptosis in Fibroblast-Like Synoviocytes.
Copper oxide nanoparticles induce pulmonary inflammation via triggering cellular cuproptosis.
H3K18 lactylation-mediated SIX1 upregulation contributes to silica-induced epithelial-mesenchymal transition in airway epithelial cells.
Intervention and mechanism of Xiaoyin Anshen Yin in treatment of psoriasis combined with sleep disorders.
LRRK2 reduces the sensitivity to TKI and PD-1 blockade in ccRCC via activating LPCAT1.
Exosomal miR-196a-5p Secreted by Bone Marrow Mesenchymal Stem Cells Inhibits Ferroptosis and Promotes Drug Resistance of Acute Myeloid Leukemia.
Astaxanthin Alleviates Lung Injury by Regulating Oxidative Stress, Inflammatory Response, P2X7 Receptor, NF-κB, Bcl-2, and Caspase-3 in LPS-Induced Endotoxemia.
Membrane biomimetic nanoenzyme-incorporated hybrid glycyrrhizic acid hydrogel for precise mitochondrial ROS scavenging for osteoarthritis treatment.
Endoscopic nasal delivery of engineered endothelial progenitor cell-derived exosomes improves angiogenesis and neurological deficits in rats with intracerebral hemorrhage.
A pectic polysaccharide from wax gourd peel improves ethanol-induced gastric ulcer injury in mice via the PI3K/AKT signaling pathway.
Environmental responsive dual-drug synergistic and dual-targeted polymer micelles based on chondroitin sulfate for treatment of breast cancer.
Downregulation of forkhead box O1 (FOXO1) acetylation ameliorates cognitive dysfunction by inhibiting endoplasmic reticulum stress-regulated neuronal apoptosis in APP/PS1 transgenic mice.
Mechanistic study of Liquiritigenin inhibiting bladder cancer cell proliferation and migration by regulating STING1.
Human transmembrane protein 68 links triacylglycerol synthesis to membrane lipid homeostasis.
Comprehensive analysis indicates DDX46 as a novel biomarker for the prognosis of lung adenocarcinoma.
Monoclonal Antibodies to Thyrotropin Receptor With Thyroid-Stimulating Activity Activate the NF-κB Pathway to Induce Chemokine Expression.
MiR214-3p Ameliorates Diabetic Cardiomyopathy by Inhibiting Ferroptosis.
Senescent cartilage endplate stem cells-derived exosomes induce oxidative stress injury in nucleus pulposus cells and aggravate intervertebral disc degeneration by regulating FOXO3.
Resveratrol ameliorates high‑fat diet‑induced insulin resistance via the DDIT4/mTOR pathway in skeletal muscle.
Interaction of osteopontin with α-lactalbumin and their synergistic effects in protecting intestinal barrier injury.
Echinococcus granulosus antigen B regulates T-cell function through inhibition of signal transducer and activator of transcription 3 in experimental immune thrombocytopenia.
Extracellular pH is a critical regulator of osteoclast fusion, size and activation.
OTUD7B controls oxLDL uptake by stabilizing Lox-1 in THP-1 and U937 cells.
LACC1 Enhances Polyamine Immunometabolism in Inflammatory Macrophages to Inhibit Atherosclerosis Progression.
Toxoplasma TgCtwh3 Δrop16 (Ⅰ/Ⅲ) accelerates neuronal apoptosis and APP production in mouse with acute infection.
Full-length Chd1 of Coprinopsis cinerea is expressed after the dark period required for fruiting body maturation and impacts meiotic progression.
SRSF7 promotes pulmonary fibrosis through regulating PKM alternative splicing in lung fibroblasts.
Ethyl caffeate alleviates inflammatory response and promotes recovery in septic-acute lung injury via the TNF-α/NF-κB/MMP9 Axis.
Glycoside components promote endothelial progenitor cell-derived exosomes repairing damaged vascular endothelium via the PI3K/AKT signaling pathway.
Huang-Lian-Jie-Du decoction inhibits CD4+ T cell infiltration into CNS in MCAO rats by regulating BBB.
Influence of α-Linolenic Acid on the Intestinal Barrier Integrity and Intestinal Antioxidant Status in Broilers.
Dimethyl Itaconate Alleviates Escherichia coli-Induced Endometritis Through the Guanosine-CXCL14 Axis via Increasing the Abundance of norank_f_Muribaculaceae.
Anti-Osteoporosis Activity of Lycopene Through ESR1: Network Pharmacology, Molecular Docking, Imaging Technology, and Experimental Validation.
Transient pharmacological inhibition of SUMOylation during pregnancy induces craniofacial malformations in offspring mice.
Rhein induces apoptosis of AGS and MGC803 cells by regulating the Ras/PI3K/AKT and p38/MAPK signaling pathway.
SMARCB1 orchestrates cellular plasticity and oncogenic pathways in typical and chondroid chordomas.
Microglia modulate integrity of myelin and proliferation of oligodendrocyte precursor cells in murine model of bone cancer pain.
miR-210 Regulates Autophagy Through the AMPK/mTOR Signaling Pathway, Reduces Neuronal Cell Death and Inflammatory Responses, and Enhances Functional Recovery Following Cerebral Hemorrhage in Mice.
Metformin attenuated sepsis-related liver injury by modulating the DNA methylation and hydroxymethylation landscape.
RBM15 promotes m6A methylation and stability of KLF6 mRNA to accelerate pyroptosis of retinal ganglion cells in early-stage diabetic retinopathy.
Effects of electroacupuncture on neural function and the expression of inflammation-related proteins NLRP3/caspase-1 in rats with ischemic stroke.
In Situ Delivery of Gasdermin E mRNA Promotes Antitumor Immunity via Creatine-Elicited Type I Interferon Signaling in Monocytes.
Identification of molecular subtypes and a prognostic risk model based on mitochondrial dynamic related genes in clear cell renal cell carcinoma.
CRM1 mediates the nuclear export of YTHDF2.
Propofol Modulates Microglial Glucose Metabolism Via the AMPK/HIF-1α Signaling Pathway To Ameliorate ECS-induced Cognitive Deficits in Depressive-like Rats.
NR5A1 Deficiency Leads to Decidualization Dysregulation of Stromal Cells and Recurrent Spontaneous Abortion During Early Pregnancy.
Mitigation of Ferroptosis in Diabetic Kidney Disease Through Mesenchymal Stem Cell Intervention via the Smad2/3/METTL3/S1PR1 Axis.
Deficiency of LPCAT3 Compromises Endometrial Stromal Cell Decidualization in Polycystic Ovary Syndrome.
Indigenous Wild Edible Mushrooms: Unveiling the Chemical Compositions and Health Impacts.
Sesamin improved growth and overall health in young animals by enhancing gut-liver axis function.
Up-regulated vitronectin in Kawasaki disease shock syndrome serves as a potential biomarker.
Saroglitazar Ameliorates Pulmonary Fibrosis Progression in Mice by Suppressing NF-κB Activation and Attenuating Macrophage M1 Polarization.
Reduced NRF2/Mfn2 activity promotes endoplasmic reticulum stress and senescence in adipose-derived mesenchymal stem cells in hypertrophic obese mice.
Flos lonicerae polysaccharide alleviates inflammatory bowel disease by improving intestinal microbiota and inhibiting oxidative stress and the NF-κB pathway.
Narirutin attenuates LPS-induced neuroinflammatory responses in both microglial cells and wild-type mice.
The matrix of exosomes: Decoding the role of miRNA in macrophage polarization and oxidative stress.
GDF15 suppresses abdominal aortic aneurysm by upregulating AREG expression to adjust macrophage polarization.
IL-33 alleviates corneal nerve damage in herpes simplex keratitis.
Rebastinib attenuates acute lung injury by promoting NLRP3 ubiquitination and blocking NLRP3/GSDMD signaling pathway in macrophages and protecting alveolar epithelial cells.
NOX2/NLRP3-Inflammasome-Dependent Microglia Activation Promotes As(III)-Induced Learning and Memory Impairments in Developmental Rats.
Upregulated BAP31 Links to Poor Prognosis and Tumor Immune Microenvironment in Breast Cancer.
Betulinic Acid Reduces Intestinal Inflammation and Enhances Intestinal Tight Junctions by Modulating the PPAR-γ/NF-κB Signaling Pathway in Intestinal Cells and Organoids.
Pretreatment with Citrus reticulata 'Chachi' Polysaccharide Alleviates Alcohol-Induced Gastric Ulcer by Inhibiting NLRP3/ASC/Caspase-1 and Nrf2/HO-1 Signaling Pathways.
ESRP1 exerts anti-tumor role by promoting ferroptosis in diffuse-type gastric cancer.
Spatiotemporal Circadian Oscillator Manipulation for Enhanced Ovarian Cancer Therapy Using a Versatile Nanoplatform.
NR4A3 suppresses bladder cancer progression by modulating autophagy via the PI3K/AKT/mTOR pathway.
Promotion of sleep by cinnamic acid in parachlorophenylalanine-induced insomnia in rats.
Modulating systemic anti-inflammatory response mitigates osteoarthritis progression and associated pain after low-dose radiotherapy.
Halicin Reduces the Warburg Effect and Overcomes Drug Resistance by Activating the Pyruvate Kinase M2 Pathway for Triple-Negative Breast Cancer Treatment.
Hypothalamic kisspeptin alleviates myasthenia gravis by regulating Th1/Th17/Treg balance through Inhibition of NF-κB signaling pathway.
Alternative splicing of uromodulin enhances mitochondrial metabolism for adaptation to stress in kidney epithelial cells.
Tiliroside induces ferroptosis and suppresses tumor growth by synergistically targeting AKR1B1 and modulating iron metabolism in ovarian cancer cells.
Human Amniotic Fluid-Derived Exosomes Alleviate Neuropathic Pain by Inducing an Anti-Inflammatory Transition in Microglia.
Luteolin Potentially Alleviates Methamphetamine Withdrawal-Induced Negative Emotions and Cognitive Deficits Through the AKT/FOXO1/HO-1 Signaling Pathway in the Prefrontal Cortex and Caudate Putamen.
Excitation-inhibition imbalance in the auditory cortex causes sound recognition impairment in noisy environment in hidden hearing loss mice.
Adipose-derived stem cells extracellular vesicles enhance diabetic wound healing via CCN2/PI3K/AKT pathway: therapeutic potential and mechanistic insights.
Overexpression of the circadian gene Bmal1 regulates the Nrf2/HO-1 oxidative stress pathway to alleviate inflammation and apoptosis in PC12 cells following cerebral ischemia-reperfusion injury.
Lysine-Targeted Covalent Strategy Leading to the Discovery of Novel Potent PROTAC-Based PI3Kδ Degraders.
Discovery of Highly Potent, Selective, and Liver-Targeting HSD17B13 Inhibitor with Robust In Vivo Anti-MASH Activity.
Psoraleae Fructus affects the livers of normal and ulcerative colitis rats differently by altering bile acid metabolism.
FOXO1 contributes to cigarette smoke condensate-induced cellular senescence and fibrosis in lung fibroblasts through activating the TGF-β1/Smad2/3 signaling pathway.
A Dual-Factor Scaffold for Spinal Cord Injury Repair Targeting Inflammation and Ferroptosis.
Potential targets for synergistic bipolar irreversible electroporation in tumor suppression through transcriptomics and proteomics analysis.
Durable HTT silencing using non-evolved dCas9 epigenome editors in patient-derived cells.
The gut microbiota-mediated ferroptosis pathway: a key mechanism of ginsenoside Rd against metabolism-associated fatty liver disease.
Mesenchymal Stem Cell-Derived Mitochondrial Transfer Promotes Tip Cell Phenotype via Glutathione Metabolic Reprogramming in Stroke Mice.
Discovery and characterization of novel FAK inhibitors for breast cancer therapy via hybrid virtual screening, biological evaluation and molecular dynamics simulations.
A novel MMP-9 inhibitor exhibits selective inhibition in non-small-cell lung cancer harboring EGFR T790M mutation by blocking EGFR/STAT3 signaling pathway.
Tarm1 may affect colitis by regulating macrophage M1 polarization in a mouse colitis model.
UGDH promotes 5-fluorouracil resistance in colorectal cancer via the ROS-activated PI3K/AKT-EEF1A2-PRDX1 pathway.
Pharmacological inhibition of Septins with Forchlorfenuron attenuates thrombus formation in experimental thrombotic mice models with modulating multiple signaling pathways in platelets.
Potential of Ginger Oil to Prevent 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone-Induced Lung Cancer Through Gut Microbiota Modulation and Inflammatory Response Inhibition.
PELI1 silencing delays intervertebral disc degeneration by impeding nucleus pulposus cell death.
SERP1 Alleviates Cerebral Ischemia/Reperfusion Injury by Inhibiting ER Stress-Mediated Apoptosis.
Deubiquitinase TRIM44 Promotes Autophagy-Mediated Chemoresistance in Diffuse Large B Cell Lymphoma.
Advanced N-glycoproteomics and proteomics approach revealed sexually dimorphic molecular signatures in primary mouse hepatocyte.
Modulation of SUMO1-TOP1 DNA damage repair by TOPORS following ovalbumin-induced oxidative stress in macrophages.
Inhibition of circ_0127646 Enhanced the Cisplatin Sensitivity in Osteosarcoma Cells via miR-22/KAT6B Axis.
Small extracellular vesicles from adipose derived stem cells alleviate microglia activation and improve motor deficit of Parkinson's disease via miR-100-5p/DTX3L/STAT1 signaling axis.
Methacrylated sericin/methacrylated hyaluronic acid composite microneedles with exosomes for diabetic wound healing.
Targeting PD-L1 for Ischemic Stroke Recovery: Age-Dependent Modulation of Immune and BBB Pathways.
Xuefu Zhuyu Decoction Improves Blood-Brain Barrier Integrity in Acute Traumatic Brain Injury Rats via Regulating Adenosine.
Porcine reproductive and respiratory syndrome virus nsp2-related proteins induce host translational arrest by specifically impairing the mTOR signaling cascade.
Transthyretin, a novel prognostic marker of POCD revealed by time-series RNA-sequencing analysis.
Melatonin ameliorates heat stress-induced oxidative apoptosis in mouse spermatocytes via autophagy and ferroptosis pathways.
Protein succinylome analysis identifies citrate synthase as a central regulator of osteoclast metabolic activity.
A novel IgD-FcδR blocker, IgD-Fc-Ig fusion protein, effectively alleviates abnormal activation of T cells the disease progression in systemic lupus erythematosus.
Vascular cellular senescence in human atherosclerosis: The critical modulating roles of CDKN2A and CDK4/6 signaling pathways.
Nicotinamide mononucleotide mitigates hyperoxia-aggravated septic lung injury via the GPx4-mediated anti-ferroptosis signaling pathway in alveolar epithelial cells.
Identification of cytochrome P450 2E1 as a novel target in neuroinflammation and development of its inhibitor Q11 as a treatment strategy.
Liyan Kaiyin Formula relieves reflux pharyngitis by regulating M1 macrophage polarization via the NF-κB/NLRP3 pathway.
Phellodendrine chloride alleviates gouty arthritis through IL-6/STAT3 signaling pathway.
Therapeutic time window of sodium of Danshensu on cerebral ischemia and its mechanism of inhibiting oxidative stress and ferroptosis through Nrf2 pathway.
Curcumin modulates the PTEN/PI3K/AKT pathway to alleviate inflammation and oxidative stress in PM2.5-Induced chronic obstructive pulmonary disease.
cba-miR-222-3p involved in photoperiod-induced apoptosis in testes of striped hamsters by targeting TRAF7.
Thermo-responsive nano-hydrogel-based delivery of Saikosaponin a to enhance anti-PD-1 therapy in osteosarcoma.
Integrating LC-MS and molecular docking technology to investigate the effect of Spatholobi caulis flavonoids in alleviating primary dysmenorrhea via regulating the RhoA/ROCK pathway.
Anti-inflammatory mechanism of Achyranthes longifolia extract and its component chikusetsusaponin IVa by modulating Nrf2/NF-κB pathways in vitro and in vivo.
Guaiane sesquiterpenoid-Glucozaluzanin C from Ainsliaea fragrans Champ. targets TLR4/p65 to regulate NF-κB/MAPK pathway, alleviating sepsis-induced acute liver injury.
NRF2 modulates WNT signaling pathway to enhance photodynamic therapy resistance in oral leukoplakia.
Role of UBC9 in the inflammatory response and pathogen susceptibility in zebrafish.
Proteomics suggests the role of Cxcl12 secreted by hucMSCs in the treatment of lipopolysaccharide-acute lung injury.
Design, synthesis, and antitumor activity of novel thioheterocyclic nucleoside derivatives by suppressing the c-MYC pathway.
Diosmetin attenuates the ubiquitination of epidermal hypoxia-inducible factor 1 alpha by diminishing the formation of RhoBTB3/PHD2 complex in ultraviolet radiation-induced sunburn in mice.
Refined qingkailing attenuates reactive astrocytes and glial scar formation after ischemia stroke via the EGFR/PLCγ pathway.
Peiyuan Ningshen-ointment alleviates learning and memory impairment induced by sleep deprivation through activating the cAMP/PKA signaling pathway.
Catharanthine tartrate ameliorates osteoclastogenesis by destabilizing HIF-1α.
Analysis of the Aerial Parts of Millettia speciosa Champ. and Mechanistic Study of Its Active Ingredient Formononetin in Improving Metabolic Syndrome.
Mechanism of antithrombin deficiency due to the novel variant C32W in the C-terminus of the signal peptide.
CNS Mitochondria-Derived Vesicle in Blood: Potential Biomarkers for Brain Mitochondria Dysfunction.
Genetic Regulation of Alternative Polyadenylation Provides Novel Insights into Molecular Mechanisms Underlying Non-small Cell Lung Cancer.
Lactate production by tumor-resident Staphylococcus promotes metastatic colonization in lung adenocarcinoma.
ELAVL1-mediated USP29 mRNA degradation activates TAK1 driving M1 microglial polarization and neural stem cell differentiation dysregulation in spinal cord injury.
Acevaltrate as a novel ferroptosis inducer with dual targets of PCBP1/2 and GPX4 in colorectal cancer.
Hydroxychloroquine improves manifestation of PE rats under oxidative stress by regulating the PI3K/AKT/mTOR signaling pathway to inhibit autophagy.
FGF13 prevents age-related hearing loss by protecting spiral ganglion neurons and ribbon synapses from injury.
Adipocytes-induced ANGPTL4/KLF4 axis drives glycolysis and metastasis in triple-negative breast cancer.
Cholesterol confers resistance to Apatinib-mediated ferroptosis in gastric cancer.
Aerobic exercise alleviates cognitive impairment in T2DM mice through gut microbiota.
Nanosilicates promote angiogenesis through activation of ROS-mediated WNT/β-catenin pathway.
An Integrated Analysis of Transcriptomics and Metabolomics Elucidates the Role and Mechanism of TRPV4 in Blunt Cardiac Injury.
Exercise-induced lactate suppresses ccRCC via CNDP2-mediated depletion of intracellular amino acids.
GPR146 regulates CYP7A1 transcription in cells and in vivo of mice.
miR-708-5p Attenuates Osteoarthritis Progression via Multi-Target Modulation of the NOX4/NF-κB Axis and Cartilage Homeostasis.
Mefunidone treats pulmonary fibrosis by targeting SDH to regulate fibro-promoting macrophages.
Dual Role of Quercetin in Promoting Early Wound Healing via Inhibiting Inflammatory Factors and Attenuating Scar Formation by Suppressing Myofibroblast Differentiation.
Dysfunction of Autophagy in Adipose Tissue Macrophages Regulated via FoxO1 in Obesity-Related Severe Acute Pancreatitis.
The promoting effect of high-fat diet-induced trained immunity on ulcerative colitis and the mechanism of the therapeutic effect of Dahuang Mudan Decoction.
Dahuang Huanglian Decoction alleviates dysbiosis by inhibiting GBP5/NLRP3 signaling pathway-mediated pyroptosis of colonic epithelial cells.
Exploring the mechanism of feiyanning formula and its extract apigenin against EGFR-TKIs resistance in non-small cell lung cancer based on UPLC-HRMS and experimental validation.
Cornus officinalis loganin attenuates acute lung injury in mice via regulating the PI3K/AKT/NLRP3 axis.
Lichong Decoction represses colorectal cancer progression via inhibiting the PINK1/Parkin pathway regulated by Rab27B.
KRAS amplification in colorectal cancer: correlations with clinicopathological features and prognosis in patients and prediction of response to targeted therapy.
1,6-Digalloyl glucose in Emblica officinalis increases the proliferation of human keratinocytes and fibroblasts with upregulated expression of periostin.
DSS1 inhibits autophagy to activate epithelial-mesenchymal transition in a pro-metastatic niche of renal cell carcinoma.
METTL3 regulates PRRSV replication by suppressing interferon beta through autophagy-mediated IKKε degradation.
TGF-β/snail-mediated epithelial-to-mesenchymal transition disrupts estradiol metabolism through suppressing the HSD17B2 expression in endometriotic epithelial cells.
Investigation of the molecular mechanism of Xiaoluo Wan in thyroid-associated ophthalmopathy: network analysis and in vivo study.
The MFGE8/integrin β3 axis mitigates experimental neutrophilic asthma by suppressing NLRP3-Caspase-1 pathway-mediated NETosis.
High-Fat Diet-Induced Diabetic Cardiomyopathy in Female Zebrafish: Cardiac Pathology and Functional Decline Mediated by Type 2 Diabetes.
Non-invasive assessment of stem cell DNA integrity in response to environmental stressors.
Macrophage migration inhibitory factor mediates joint capsule fibrosis via facilitating phospholipid metabolite PGE2 production in fibroblasts.
Reactive oxygen species regulate adipose-osteogenic lineage commitment of human mesenchymal stem cells by modulating gene expression of C/EBP homology protein and aldo-keto reductase family 1 member A1.
Secreted phosphoprotein 1 promotes the activation of keloid fibroblasts via the CD44/TGF-β1/Smad pathway.
MS275 Inhibits Neuroblastoma Cell Growth by Mediating H3K27ac/PROX1 Axis In Silico and In Vitro.
Peptide Cy(RL-QN15) alleviates UVB-induced skin aging by promoting the repair of barrier.
S-COS-Se mitigates cadmium-induced oxidative stress, inflammation, and immunotoxicity by restoring immune balance and inhibiting mitochondria-pyroptosis crosstalk.
Exosomes derived from ALR-modified adipose mesenchymal stem cells mediate hepatoprotective effects on hepatic ischemia-reperfusion injury by promoting regeneration and protecting mitochondria.
Kushenol I combats ulcerative colitis via intestinal barrier preservation and gut microbiota optimization.
Negative Air Ions Attenuate Nicotine-Induced Vascular Endothelial Dysfunction by Suppressing AP1-Mediated FN1 and SPP1.
Selenium binding protein 1 (SBP1) suppresses fructose-induced metabolic dysfunction-associated steatotic liver disease.
Alleviation of fibrosis and oxidative stress in pressure overload-induced cardiac remodeling and heart failure via SIRT3 activation by colchicine.
The Antidiabetic Mechanisms of Cinnamon Extract: Insights from Network Pharmacology, Gut Microbiota, and Metabolites.
Construction of a macrophage-related prognostic signature and assessment of immune checkpoint inhibitor efficacy of HCC.
Beta sitosterol inhibits the proliferation and migration of synoviocytes in rheumatoid arthritis via lactylation of GPI.
Tanshinone IIA induces oxidative stress in trophoblast cells and enhances copper dependent death.
Pharmacological evaluation of physcion as a TRPV1 inhibitor with multimodal analgesic efficacy in experimental pain models.
Transformable albumin-based nanocapsules selectively amplify tumor starvation and disulfidptosis through metabolic deception.
Mesenchymal stem cell-secreted KGF ameliorates acute lung injury via the Gab1/ERK/NF-κB signaling axis.
MTMR14 depletion aggravates intrapulmonary inflammation and emphysema in experimental COPD through activating macrophage M1 polarization.
Neutrophil membrane-coated circular RNA nanoparticles for targeted immunotherapy in HER2-positive breast cancer brain metastasis.
In vivo CRISPR screening identifies POU3F3 as a novel regulator of ferroptosis resistance in hepatocellular carcinoma via retinoic acid signaling.
TRIM29 alleviates intervertebral disc degeneration through the PI3K/AKT/mTOR pathway.
Taurine Attenuates Disuse Muscle Atrophy Through Modulation of the xCT-GSH-GPX4 and AMPK-ACC-ACSL4 Pathways.
Fragaria orientalis attenuates hepatic fibrosis through modulation of FXR/CYP7A1, ERK/p38 MAPK, and TLR4/MyD88/NF-κB signaling in rats.
miR-92a-1-5p targets MEF2A to induce insulin resistance in myocardial ischemia/reperfusion injury.
Trim65 mitigates doxorubicin-induced myocardial injury by reducing ferroptosis.
TFE3-mediated lysosomal biogenesis and homeostasis alleviates arsenic-induced lysosomal and immune dysfunction in macrophages.
Maternal lead exposure impairs offspring growth and intestinal microbiota via AMPK/ULK1 pathway activation.
Bioinformatics identification of key microRNA-correlated genes associated with hepatocellular carcinoma heterogeneity and prognosis.
Self-reinforced piezoelectric chip for scaffold-free repair of critical-sized bone defects.
Prominin-2/FBXO22/BACH1 axis protects bone marrow mesenchymal stem cells against TBHP-induced ferroptosis and ameliorates intervertebral disc degeneration.
Identification of a ferroptosis related genes signature and GDF15 contributing to a new perspective for the diagnosis of CRPC.
Phochinenin I, a Bioactive Constituent from Pholidota chinensis, Attenuates Inflammatory Response and Oxidative Stress In Vitro and In Vivo.
Excessive accumulation of thioredoxin promotes osteogenic differentiation of mesenchymal stem cells of ligament in ankylosing spondylitis by upregulating autophagy levels.
LASP1 inhibits the formation of NETs and alleviates acute pancreatitis by stabilizing F-actin polymerization in neutrophils.
PCSK9 promotes vascular neointimal hyperplasia through non-lipid regulation of vascular smooth muscle cell proliferation, migration, and autophagy.
Astrocytes-Secreted WNT5B Disrupts the Blood-Brain Barrier Via ROR1/JNK/c-JUN Cascade During Meningitic Escherichia Coli Infection.
Wnt5a promotes VM formation by modulating the stemness and EMT progression of prostate cancer cell.
Characteristics of polycystic ovary syndrome rat models induced by letrozole, testosterone propionate and high-fat diets.
Bromocriptine sensitivity in bromocriptine-induced drug-resistant prolactinomas is restored by inhibiting FGF19/FGFR4/PRL.
ARC protects cochlear hair cells from neomycin-induced ototoxicity via the Ras/JNK signaling pathway.
Tumor-Specific Protein Induced in Situ Self-Assembly of Peptide Drugs for Synergistic Mitochondria Disruption.
Huanglian-Renshen-Decoction Maintains Islet β-Cell Identity in T2DM Mice through Regulating GLP-1 and GLP-1R in Both Islet and Intestine.
Inhibiting UGCG prevents PRV infection by decreasing lysosome-associated autophage.
Tumor-Derived GDF15 Induces Tumor Associated Fibroblast Transformation From BMSCs and Fibroblasts in Oral Squamous Cell Carcinoma.
ROS Responsive Cerium Oxide Biomimetic Nanoparticles Alleviates Calcium Oxalate Crystals Induced Kidney Injury via Suppressing Oxidative Stress and M1 Macrophage Polarization.
Macrophage autophagy protects against acute kidney injury by inhibiting renal inflammation through the degradation of TARM1.
Macrophage-derived amphiregulin promoted the osteogenic differentiation of chondrocytes through EGFR/Yap axis and TGF-β activation.
PIEZO1 mediates matrix stiffness-induced tumor progression in kidney renal clear cell carcinoma by activating the Ca(2+)/Calpain/YAP pathway.
Ingenane diterpenoids with anti-inflammatory activity from Euphorbia antiquorum.
EHMT2-mediated R-loop formation promotes the malignant progression of prostate cancer via activating Aurora B.
Free fatty acid receptor-4 regulates T-cell-mediated allogeneic reaction through activating an aryl hydrocarbon receptor pathway.
Sappanone A alleviates metabolic dysfunction-associated steatohepatitis by decreasing hepatocyte lipotoxicity via targeting Mup3 in mice.
Downregulation of cardiac inflammation via the CaMKII δ/NF-κB pathway in heart failure by Lonicerae Japonicae Flos and Angelicae Sinensis Radix.
Asiaticoside alleviated NAFLD by activating Nrf2 and inhibiting the NF-κB pathway.
Ginsenoside RK3 inhibits glioblastoma by modulating macrophage M2 polarization via the PPARG/CCL2 axis.
Multi-omics analysis reveals the protective effects of Chinese yam polysaccharide against cisplatin-induced renal interstitial fibrosis.
The double face of licorice-kansui herb pair: Cure or curse, depending on the combining ratio and mediated by hydrogen sulfide.
Phlorizin ameliorates cognitive and behavioral impairments via the microbiota-gut-brain axis in high-fat and high-fructose diet-induced obese male mice.
Nanodrug-Engineered Exosomes Achieve a Jointly Dual-Pathway Inhibition on Cuproptosis.
Cupric Doping Hollow Prussian Blue Nanoplatform for Enhanced Cholesterol Depletion: a Promising Strategy for Breast Cancer Therapy and Metastasis Inhibition.
Knockdown of integrin β1 inhibits proliferation and promotes apoptosis in bladder cancer cells.
Elevated-c-MYC-expressing Fibrosarcoma Cells With Acquired Gemcitabine Resistance Remain Sensitive to Recombinant Methioninase: A Potential Clinical Strategy for a Recalcitrant Disease.
Gboxin Induced Apoptosis and Ferroptosis of Cervical Cancer Cells by Promoting Autophagy-Mediated Inhibition of Nrf2 Signaling Under Low-Glucose Conditions.
Network pharmacology uncovers that secoisolariciresinol diglucoside ameliorate premature ovarian insufficiency via PI3K/Akt pathway.
Chemerin-9 is neuroprotective in APP/PS1 transgenic mice by inhibiting NLRP3 inflammasome and promoting microglial clearance of Aβ.
Alantolactone mitigates the elevation of blood pressure in mice induced by angiotensin II by inhibiting calcium channel activation.
Neutrophil membrane-coated nanoparticles for targeted delivery of toll-like receptor 4 siRNA ameliorate LPS-induced acute lung injury.
Astragaloside IV plays a neuroprotective role by promoting PPARγ in cerebral ischemia-reperfusion rats.
Puerarin pretreatment provides protection against myocardial ischemia/reperfusion injury via inhibiting excessive autophagy and apoptosis by modulation of HES1.
Astragali Radix-Angelicae Sinensis Radix inhibits the activation of vascular adventitial fibroblasts and vascular intimal proliferation by regulating the TGF-β1/Smad2/3 pathway.
Saffron extract alleviates D-gal-induced late-onset hypogonadism by activating the PI3K-Akt-Nrf2 signaling pathway.
6-Shogaol attenuates cisplatin induced emesis by inhibiting the mtDNA-cGAS-STING signaling pathway in a rat pica model.
Nociceptor-localized KCC2 suppresses brachial plexus avulsion-induced neuropathic pain and related central sensitization.
Mechanistic insights into Suanzaoren Decoction's improvement of cardiac contractile function in anxiety-induced cardiac insufficiency.
Dehydrocorydaline attenuates myocardial ischemia-reperfusion injury via the FoXO signalling pathway: A multimodal study based on network pharmacology, molecular docking, and experimental study.
Therapeutic potential of Rosa roxburghii folium extract in insomnia treatment: a comprehensive evaluation of behavioral and neurochemical effects in a PCPA-induced mouse model.
The histone demethylase KDM5C enhances the sensitivity of acute myeloid leukemia cells to lenalidomide by stabilizing cereblon.
Dual-mode-driven nanomotors targeting inflammatory macrophages for the MRI and synergistic treatment of atherosclerosis.
Transketolase attenuates the chemotherapy sensitivity of glioma cells by modulating R-loop formation.
The regulatory role of the Netrin-1/UNC5H3 pathway in neuronal pyroptosis after stroke.
Interleukin 8 exacerbates age-related hearing loss through regulating perivascular-resident macrophage-like melanocytes viability and the permeability of the endothelial cells.
Dihydromyricetin ameliorates neurotoxicity induced by high glucose through restraining ferroptosis by inhibiting JNK-inflammation pathway in HT22 cells.
The RNA Demethyltransferase FTO Regulates Ferroptosis in Major Depressive Disorder.
MC-LR induces and exacerbates Colitis in mice through the JAK1/STAT3 pathway.
Antigen B from Echinococcus granulosus regulates macrophage phagocytosis by controlling TLR4 endocytosis in immune thrombocytopenia.
Icaritin alleviates motor impairment and osteoporosis in Parkinson's disease mice via the ER-PI3K/Akt pathway.
Intermittent Fasting Improves Sevoflurane-Induced Cognitive Dysfunction in Rats Through SIRT1-Mediated Autophagy.
Idebenone Protects Photoreceptors Impaired by Oxidative Phosphorylation Disorder in Retinal Detachment.
Bifidobacterium breve synergizes with Akkermansia muciniphila and Bacteroides ovatus to antagonize Clostridioides difficile.
L3MBTL3 and STAT3 collaboratively upregulate SNAIL expression to promote metastasis in female breast cancer.
Bi-allelic variants in DAP3 result in reduced assembly of the mitoribosomal small subunit with altered apoptosis and a Perrault-syndrome-spectrum phenotype.
Clinical significance and pro-oncogenic function of DBF4 in clear cell renal cell carcinoma.
IFNγ regulates ferroptosis in KFs by inhibiting the expression of SPOCD1 through DNMT3A.
The therapeutic potential of Osmundacetone for rheumatoid arthritis: Effects and mechanisms on osteoclastogenesis.
RFWD2 increases proliferation and CDDP resistance of osteosarcoma cells.
Targeting METTL8 with Rabdosiin overcomes lenvatinib resistance in hepatocellular carcinoma.
Prolonged tamoxifen treatment induces iron deposition and ferroptosis in the liver.
A multidimensional pan-cancer analysis of NDUFA4L2 and verification of the oncogenic value in colon cancer.
Cardiotoxicity of polystyrene nanoplastics and associated mechanism of myocardial cell injury in mice.
Protective effects of Notoginsenoside R2 on reducing lipid accumulation and mitochondrial dysfunction in diabetic nephropathy through regulation of c-Src.
Two Small Peptides from Buthus martensii Hydrolysates Exhibit Antitumor Activity Through Inhibition of TNF-α-Mediated Signal Transduction Pathways.
EIF4A3-Mediated circ_0008126 Inhibits the Progression and Metastasis of Gastric Cancer by Modulating the APC/β-Catenin Pathway.
Deapioplatycodin D inhibits glioblastoma cell proliferation by inducing BNIP3L-mediated incomplete mitophagy.
Blockade of TIPE2-Mediated Ferroptosis of Myeloid-Derived Suppressor Cells Achieves the Full Potential of Combinatory Ferroptosis and Anti-PD-L1 Cancer Immunotherapy.
Identification of Novel 58-5p and SREBF1 Interaction and Effects on Apoptosis of Ovine Ovarian Granulosa Cell.
Molecule interacting with CasL-2 enhances tumor progression and alters radiosensitivity in cervical cancer.
Dentin tubules as a long-term sustained release carrier to accelerate bone repair by loading FTY720.
Pluripotent polysaccharide coordinated hydrogels remodel inflammation, neovascularization and reepithelization for efficient diabetic wound prohealing.
Semen Strychni Pulveratum and vomicine alleviate neuroinflammation in amyotrophic lateral sclerosis through cGAS-STING-TBK1 pathway.
Human leukocyte antigen DR alpha inhibits renal cell carcinoma progression by promoting the polarization of M2 macrophages to M1 via the NF-κB pathway.
The protective roles of eugenol on type 1 diabetes mellitus through NRF2-mediated oxidative stress pathway.
Selenoprotein M protects cardiac endothelial cell integrity against high-glucose stress via enhancing Parkin-mediated mitophagy.
Using chondroitin sulfate lithium hydrogel for diabetic bone regeneration via regulation of macrophage polarization.
Bleomycin pollution and lung health: The therapeutic potential of peimine in bleomycin-induced pulmonary fibrosis by inhibiting glycolysis.
Synthesis and anti-tumor activity of menthylamine derivatives: Focusing on the potent inhibitory effect of compound W8 on glioma growth.
Therapeutic Potential of Vanillic Acid in Ulcerative Colitis Through Microbiota and Macrophage Modulation.
Integrating Network Pharmacology and In Vitro Experimental Verification Revealing Bushenhuoxue Recipe Against Intrauterine Adhesions via PI3K-AKT Signaling Pathway.
USP2 Promotes the Proliferation and Inflammation of Fibroblast-Like Synovial Cells in Rheumatoid Arthritis Through Deubiquitination of TRAF2.
Involvement of Histone Acetyltransferase 1 (HAT1) in the Spermatogenesis of Non-Condensed Nuclear Sperm in Chinese Mitten Crab, Eriocheir sinensis.
Rosiglitazone Promotes Oligodendrocyte Development and Myelin Formation of Repeated Neonatal Sevoflurane Exposure via PPARγ Signaling.
Jinlida granules alleviate podocyte apoptosis and mitochondrial dysfunction via the AMPK/PGC‑1α pathway in diabetic nephropathy.
Inhibition of DNA Methyltransferase DNMT1 Reverses Th2 Response Polarisation and Alleviates Allergic Rhinitis.
T-2 toxin triggers immunotoxic effects in goats by inducing ferroptosis and neutrophil extracellular traps.
Neuregulin 1 improved gastric motility and reduced gastric inflammation by activating the α7nAChR through the cholinergic anti-inflammatory pathway in diabetic rats.
ATP6V1B1 regulates ovarian cancer progression and cisplatin sensitivity through the mTOR/autophagy pathway.
Low-dose SAHA enhances CD8(+) T cell-mediated antitumor immunity by boosting MHC I expression in non-small cell lung cancer.
Bile duct ligation impairs visual acuity in rats by ammonia- and bilirubin-induced retinal degeneration.
Network pharmacology and animal experiments revealed the protective effects of Guilong prescription on chronic prostatitis and its possible mechanisms.
Involvement of mitochondrial dysfunction and oxidative stress in the nephrotoxicity induced by high-fat diet in Sprague-Dawley rats.
Se-Methylselenocysteine Ameliorates DEHP-Induced Ferroptosis in Testicular Sertoli Cells via the Nrf2/GPX4 Axis.
Isoliquiritigenin Exhibits Anti-Inflammatory Responses in Acute Lung Injury by Covalently Binding to the Myeloid Differentiation Protein-2 Domain.
PGAM5 promotes RIPK1-PANoptosome activity by phosphorylating and activating RIPK1 to mediate PANoptosis after subarachnoid hemorrhage in rats.
Activation of PAR1 contributes to ferroptosis of Schwann cells and inhibits regeneration of myelin sheath after sciatic nerve crush injury in rats via Hippo-YAP/ACSL4 pathway.
HSP90 stabilizes visual cycle retinol dehydrogenase 5 in the endoplasmic reticulum by inhibiting its degradation during autophagy.
Multifunctional drug delivery nanoparticles for combined chemotherapy/chemodynamic/photothermal therapy against colorectal cancer through synergistic cuproptosis/ferroptosis/apoptosis.
Geniposide Protects Against Myocardial Infarction Injury via the Restoration in Gut Microbiota and Gut-Brain Axis.
Taurine mechanism in preventing retinal cell damage from acute ocular hypertension through GTPBP3 regulation.
Effects of atropine on choroidal hemodynamics and VEGFA and HIF-1α expression in form-deprivation myopia guinea pigs.
Microglia-derived Galectin-9 drives amyloid-β pathology in Alzheimer's disease.
DHA Improves neurodevelopmental abnormalities in offspring of gestational diabetes mellitus patients via the PPAR-γ/FATP4 pathway.
The effects of luteolin on orthodontic tooth movement and relapse.
Placental extracellular vesicles induce ovarian tumour cell death in an ex vivo explant model: Possible therapeutic potential.
Supramolecular prodrug inspiried by the Rhizoma Coptidis - Fructus Mume herbal pair alleviated inflammatory diseases by inhibiting pyroptosis.
Trans 10, cis 12-conjugated linoleic acid in low concentration reduces while in high concentration enhances adipocyte metabolism but effectively improves hepatic steatosis of obese mice.
Hspa13 Deficiency Impaired Marginal Zone B Cells Regulatory Function and Contributed to Lupus Pathogenesis.
Primary Cilia Formation Mediated by Hsa_Circ_0005185/OTUB1/RAB8A Complex Inhibits Prostate Cancer Progression by Suppressing Hedgehog Signaling Pathway.
In Situ Transformable Nanoparticle Effectively Suppresses Bladder Cancer by Damaging Mitochondria and Blocking Mitochondrial Autophagy Flux.
Cannabidiol alleviates the inflammatory response in rats with traumatic brain injury through the PGE (2)-EP2-cAMP-PKA signaling pathway.
Roxadustat improves diabetic myocardial injury by upregulating HIF-1α/UCP2 against oxidative stress.
Hypothermia regulates mitophagy and apoptosis via PINK1/Parkin-VDAC 3 signaling pathway during oxygen-glucose deprivation/recovery injury.
Identification of potential targets regulating neutrophil extracellular traps in acute rejection of kidney transplantation based on transcriptomics and animal experiments.
The phosphodiesterase-4 inhibitor Zl-n-91 suppresses glioblastoma growth via EGR1/PTEN/AKT pathway.
Loss of Type 2 Bone Morphogenetic Protein Receptor Activates NOD-Like Receptor Family Protein 3/Gasdermin E-Mediated Pyroptosis in Pulmonary Arterial Hypertension.
Global MicroRNA Profiling of HSV-1 Infected Cornea Identifies miR-329 as a Novel Regulator of Virus Infection.
Inhibition of LRRK2 Ameliorates Aspergillus fumigatus Keratitis by Regulating STING Signaling Pathways.
Host factor PLAC8 is required for pancreas infection by SARS-CoV-2.
Activity-based chemical proteomics reveals caffeic acid ameliorates pentylenetetrazol-induced seizures by covalently targeting aconitate decarboxylase 1.
LDHA-mediated glycolysis in stria vascularis endothelial cells regulates macrophages function through CX3CL1-CX3CR1 pathway in noise-induced oxidative stress.
Pestones A and B from a Fungus Pestalotiopsis sp. Bound to Mutant p53 and Changed Its Conformation.
Molecular Mechanism of Vine Tea Dihydromyricetin Extract on Alleviating Glucolipid Metabolism Disorder in db/db Mice: Based on Liver RNA-Seq and TLR4/MyD88/NF-κB Pathway.
Diagnostics and immunological function of CENPN in human tumors: from pan-cancer analysis to validation in breast cancer.
Hypoxia Promotes Gluconeogenesis Through PGC-1α in the Liver of Lasiopodomys brandtii.
Discovery of Novel Aromatic Urea-Imidazole Salt Derivatives for Cancer Therapy via Targeting ERK1/2.
Deletion of Xist repeat B disrupts cell cycle and asymmetric cell division through Usp9x hyperactivation in mice.
Harnessing TAGAP to improve immunotherapy for lung squamous carcinoma treatment by targeting c-Rel in CD4+ T cells.
Methionine regulates maternal-fetal immune tolerance and endometrial receptivity by enhancing embryonic IL-5 secretion.
ITIH5-mediated fibroblast/macrophage crosstalk exacerbates cardiac remodelling after myocardial infarction.
Hepatic Lamp2a deficiency promotes inflammation of murine autoimmune cholangitis via affecting bile acid metabolism.
12/15-Lipoxygenase-Derived Electrophilic Lipid Modifications in Phagocytic Macrophages.
Hypoxia-Induced VGF Promotes Cell Migration and Invasion in Prostate Cancer via the PI3K/Akt Axis.
Hesperetin alleviates PM2.5-induced lung injury by inhibiting ferroptosis in an Nrf2-dependent manner.
Paroxetine alleviates dendritic cell and T lymphocyte activation via GRK2-mediated PI3K-AKT signaling in rheumatoid arthritis.
Cornuside alleviates cognitive impairments induced by Aβ(1-42) through attenuating NLRP3-mediated neurotoxicity by promoting mitophagy.
Autism-associated ASPM variant causes macrocephaly and social-cognitive deficits in mice.
A glucose-enriched lung pre-metastatic niche triggered by matrix stiffness-tuned exosomal miRNAs in hepatocellular carcinoma.
ERS regulates endometrial epithelial cell autophagy through XBP1s-mediated activation of the PI3K/AKT pathway.
HSPB1 Orchestrates the Inflammation-Associated Transcriptome Profile of Atherosclerosis in HUVECs.
A novel piperine derivative HJJ_3_5 inhibits colorectal cancer progression by modulating EMT signaling pathways.
CircMETTL9 targets CCAR2 to induce neuronal oxidative stress and apoptosis via mitochondria-mediated pathways following traumatic brain injury.
Sulfonated albumin from hepatocytes accelerates liver fibrosis in nonalcoholic fatty liver disease through endoplasmic reticulum stress.
FADS1 inhibition protects retinal pigment epithelium cells from ferroptosis in age related macular degeneration.
Gestational diabetes mellitus-derived miR-7-19488 targets PIK3R2 mRNA to stimulate the abnormal development and maturation of offspring-islets.
Effects of electroacupuncture on microglia phenotype and epigenetic modulation of C/EBPβ in SAMP8 mice.
Micheliolide attenuates sepsis-induced acute lung injury by suppressing mitochondrial oxidative stress and PFKFB3-driven glycolysis.
HIF2α drives ccRCC metastasis through transcriptional activation of methylation-controlled J protein and enhanced prolegumain secretion.
Multi-dimensional bio mass cytometry: simultaneous analysis of cytoplasmic proteins and metabolites on single cells.
NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer's disease progression.
Mechanism of Yinxu Weitong Capsule in the treatment of precancerous lesions of gastric cancer based on network pharmacology and experimental validation.
Nano-alkaline ion-excited NETs ablative eye drops promote ocular surface recovery.
Effect of Rhei Radix Et Rhizome on treatment of polycystic ovary syndrome by regulating PI3K/AKT pathway and targeting EGFR/ALB in rats.
The chromatin remodeler Brg1 is essential for cochlear sensory epithelium differentiation and patterning.
Preliminary exploration of the C-3 galloyl group and the B-5' hydroxyl group enhance the biological activity of catechins in alleviating obesity induced by high-fat diet in mice.
Transcranial alternating current stimulation inhibits ferroptosis and promotes functional recovery in spinal cord injury via the cGMP-PKG signalling pathway.
Antibacterial chitosan/organic rectorite nanocomposite-conjugated gelatin/β-cyclodextrin hydrogels with improved hemostasis performance for wound repair.
Crucial roles of asprosin in cisplatin-induced ferroptosis and acute kidney injury.
β-Hydroxybutyrate-induced mitochondrial DNA (mtDNA) release mediated innate inflammatory response in bovine mammary epithelial cells by inhibiting autophagy.
Ginsenoside Rg1 Alleviates Hydrogen Peroxide-Induced Autophagy and Apoptosis in Ovarian Granulosa Cells.
Effect of the Deubiquitinating Peptidase 7 (USP7) on Hepatitis B Virus (HBV) Replication and the Antiviral Efficacy of Entecavir (ETV).
High glucose mediates diabetic peripheral neuropathy by inducing Schwann cells apoptosis through the Dgkh/PKC-α signaling pathway.
Expression of ORMDL1 in esophageal squamous cell carcinoma and its effect on patient outcomes: A potential biomarker and treatment target.
Integrative single-cell and spatial transcriptome analysis reveals the functions of TREM2(high) macrophages and infarct border dynamics post-myocardial infarction.
HNRNPC-Mediated m6A Epitranscriptomics Drives CD80-Dependent Tubular Dysfunction in Sepsis-Induced AKI.
Stimulator of Interferon Genes Regulates Ferroptosis and Airway Inflammation via acyl-CoA Synthetase Long-Chain Family Member 4 in Asthmatic Mice.
Pharmacological Activation of GPR68 Attenuates Ferroptosis in Spinal Cord Ischemia/Reperfusion Injury Through PI3K/Akt-Mediated Nrf2 Antioxidant Pathway.
LARS1 Promotes Tubular Epithelial Cells Epithelial Mesenchymal Transition in Chronic Kidney Disease by Inhibiting Lipophagy.
Panaxatriol saponins exert anti-renal fibrosis by suppressing TNF-α mediated inflammation and TGF-β1/Smad3 signaling pathway.
Investigation of the mechanism of Yijing Decoction in the treatment of premature ovarian insufficiency: A network pharmacology study.
Endoplasmic Reticulum Stress Exacerbates Nucleus Pulposus Cell Pyroptosis via PERK-Dependent Activation of JAK1-STAT3 Signaling.
A dual-drug sequential delivery hydrogel for programmatic microglia/macrophage polarization and function recovery in spinal cord injury.
Vitamin C-functionalized copper nanozymes for treating drug-resistant intracellular infections and hyperinflammation.
Cholesterol modified defense peptide as an EMP2-siRNA delivery system for synergistic immunogene therapy against breast cancer.
ANGPTL3 nanobody-FGF21 fusion protein ameliorates metabolic dysfunction-associated fatty liver disease via regulation of lipid and glucose metabolism and attenuation of oxidative stress.
ASIC1a Promotes nucleus pulposus derived stem cells apoptosis through modulation of SIRT3-dependent mitochondrial redox homeostasis in intervertebral disc degeneration.
Norepinephrine promotes oxidative stress in vascular adventitial fibroblasts via PKC/NFκB-mediated NOX2 upregulation.
Flavonoids from Polypodium hastatum as neuroprotective agents attenuate cerebral ischemia/reperfusion injury in vitro and in vivo via activating Nrf2.
WDR4 drives tumour-associated macrophage reprogramming and tumour progression via selective translation and membrane cholesterol efflux.
SLX1 silencing overcomes Olaparib resistance in metastatic castration-resistant prostate cancer by disrupting SLX4-mediated DNA repair complexes.
Knockdown of NDUFAF6 inhibits breast cancer progression via promoting mitophagy and apoptosis.
UHRF1 ameliorates liver cirrhosis through suppressing macrophage M1 polarization by catalyzing HMGA2 promoter methylation.
Sappanone A, a potential natural inhibitor of PI3K, alleviates metabolic dysfunction-associated steatohepatitis in experimental models.
Targeting TRAF6 inhibits cystogenesis in autosomal dominant polycystic kidney disease.
1275-nm Photobiomodulation Alleviates Brain Drainage Impairment as a Promising Therapeutic Strategy for Aging-Related Neurological Decline.
Morin alleviates sepsis-associated encephalopathy through inhibiting ferroptosis via SIRT1.
Cross-kingdom delivery and putative gene modulation of androgen pathways by plant-derived exosome-like nanoparticles from polygoni multiflori radix promotes hair growth via miRNA cargo.
Mdivi-1 promotes lipid droplets-mitochondria contact and ameliorates cardiac lipotoxicity in high-fat diet-fed mice.
Duhuo Jisheng Decoction mitigates postmenopausal rheumatoid arthritis by suppressing eEF2K-mediated cellular senescence.
Activation of endogenous PRKN by structural derepression is linked to increased turnover of the E3 ubiquitin ligase.
A study on the establishment of a traumatic brain injury model of tree shrews and the observation of neuroinflammatory responses.
Matrix stiffness-sensitive LDHA drives autophagy of pancreatic ductal adenocarcinoma via inducing FOXO3 expression and lactylation.
miR-196a-5p suppresses the MAPK/ERK pathway by targeting HOXA7 to regulate the proliferation and apoptosis of placental trophoblasts in gestational diabetes.
Lactobacillus delbrueckii Alleviate Oxidative Stress and Intestinal Injuries by Activating TLR2 and TLR4 Expressions in IPEC-J2 Cells.
Time-restricted feeding promotes glucagon-like peptide-1 secretion and regulates appetite via tryptophan metabolism of gut Lactobacillus in pigs.
Gut dysbiosis-induced vitamin B6 metabolic disorder contributes to chronic stress-related abnormal behaviors in a cortisol-independent manner.
LPS disrupts erythroid-myeloid balance in zebrafish via Jak2/Stat3-Hif1a signaling.
Genome-scale CRISPR screen identifies host factors associated with bovine parainfluenza virus 3 infection.
MicroRNA-3473b regulates corticosterone-induced microglial polarization and inflammation through TREM2.
Hypoxia-induced secretory autophagy in cancer-associated fibroblasts promotes ECM remodelling through serglycin secretion in oral squamous cell carcinoma.
Formononetin and daidzein from Huoxiangzhengqi formula ameliorate Salmonella Typhimurium-induced intestinal flora dysbiosis and barrier dysfunction.
Dietary urolithin A suppresses lung cancer via gut microbiota-mediated autophagy activation.
Adipose-derived mesenchymal stem cell exosomes protect keratinocytes from high-glucose injury by modulating KEAP1/NRF2/HO-1 axis.
Melatonin attenuates lipopolysaccharide-induced acute myocardial injury by regulating KLF4 expression.
Breast cancer cell-derived adrenomedullin confers cancer-associated adipose remodeling through the cAMP/Creb1/Zeb1 axis.
Potentiating Cerebral Perfusion Normalizes Glymphatic Dynamics in Systemic Inflammation.
Qula-derived Limosilactobacillus fermentum TD-3 and Lactococcus lactis MQ1-1 alleviate aging-related intestinal barrier dysfunction via microbiota-short-chain fatty acid-AMPK/MLCK-tight junction axis.
Intracellular interaction between FcRY receptor and IgY in ovarian vascular endothelial cells during avian maternal IgY transfer.
Genetic and functional analysis of ZMIZ1 in neurodevelopmental disorder with dysmorphic facies and distal skeletal anomalies (NEDDFSA): insights from muscle cells and signaling pathways.
A CCL5(+)CD20(+)CD8(+) T cell subset drives pathogenic transformation of synoviocytes in rheumatoid arthritis via JAK-STAT signaling.
Perfluorooctanoic acid and perfluorooctanesulfonic acid induce resistance to chemotherapy in colorectal cancer.
A shape complementarity strategy based on NCA029 enables potent HsClpP agonists for the treatment of small cell lung carcinoma.
The NAWG combinatorial strategy activates MAPK signaling to restore extracellular matrix architecture in aging skin.
Targeting FoxO1-STX17-mediated autophagic flux: Quercetin's therapeutic mechanism in diabetic nephropathy.
SMARCA5 Cooperates With RSF1 to Promote Pathological Glycolysis and Chondrocyte Dysfunction in Osteoarthritis Through ATPase-Dependent Chromatin Regulation.
Mild microwave hyperthermia promotes mitotic catastrophe, induces time-delayed cGAS-STING activation and restores sensitivity to anti-PDL1 therapy in Pan02 pancreatic cancer model.
Cigarette smoke-induced lung-brain barrier dysfunction drives neurocognitive impairment via inflammatory spill-over.
TAT-PBX1 fusion protein alleviates LPS-induced acute lung injury via AMPK-TFAM signaling activation.
Mitochondrial protease ClpP deficiency protects against tubulointerstitial damage in diabetic kidney disease.
Neutrophil extracellular traps promote bone loss in type 1 diabetes via suppression of the FN1-PI3K/Akt signaling axis.
Kaempferol inhibits atherosclerotic plaque development via dual-targeting of p53-p21-p16 senescence pathway and Nrf2/HO-1/NQO1 antioxidant mechanism: Insights from combined in vivo and in vitro research.
Selenium improves behavioral performance in a rat model of autism spectrum disorder by mitigating oxidative stress and modulating the Sirt1/Keap1/Nrf2/HO-1 signaling pathway.
Targeting TDP1 phosphorylation by the natural product imperatorin promotes DNA repair and cardiac regeneration.
Shikonin alleviates rotenone-induced Parkinson's disease neuroinflammation by targeting PKM2-mediated glycolytic MG-Hs production.
EXOSC3 knockdown induces G1/S phase arrest to suppress hepatocellular carcinoma cell proliferation.
Toxoplasma gondii-induced ferroptosis contributes to acute lung injury in mice.
ENO1-mediated deoxycytidine synthesis and gemcitabine resistance by stabilizing RRM2 in pancreatic cancer.
Butin inhibits osteoarthritis progression by modulating the Nrf2/HO-1 signaling pathway and inhibiting NF-κB signaling.
Engineered vesicles enhance oral antibiotic absorption in proximal small intestine and mitigate gut dysbiosis.
Elevated Flotillin-1 in Saliva and Salivary Glands: A Novel Non-Invasive Biomarker in an Alzheimer's Disease Mouse Model.
Cold Exposure Exacerbates Allergic Airway Inflammation via Ferroptosis: Evidence from a Murine Model.
Glutamine synthetase modulates YAP activation by stabilizing LATS under glutamine homeostasis.
GPX8 is transcriptionally regulated by KLF16 and promotes osteosarcoma progression.
Honokiol attenuates diabetic nephropathy by targeting SIRT3 to suppress mitochondrial ROS-induced pyroptosis.
Single-cell transcriptomic analysis of the heterogeneity of mesenchymal and stromal cells and their regulon alteration during airway remodeling in asthma.
Identifying CTSF and GSTM3 as chemoresistance therapeutic targets in breast cancer through multi-omics MR analysis.
Vitisin A inhibits liver fibrosis by promoting Nrf2/HO-1 pathway and inhibiting Cuproptosis.
Loss of the miR-221/222 Cluster Promotes the Pathogenesis of Osteoarthritis in Inflamed Mouse Chondrocytes and Osteoarthritis Models.
Ginkgolide B Promotes Angiogenesis After Oxygen-Glucose Deprivation by Regulating AKT1 in bEnd.3 Cells.
Semi-inductive dataset construction and framework optimization for practical drug target interaction prediction with ScopeDTI.
Deoxycholic acid derived from the gut microbiota involved in the regulation of adaptive thermogenesis in response to dietary protein restriction in plateau pika.
Haematococcus pluvialis ameliorates renal fibrosis by restoring mitophagy via PINK1-Parkin-p62-LC3 signaling.
Targeting polyamine metabolism induces oxidative/carbonyl stress to reinvigorate antitumor immunity in prostate cancer.
Fennel essential oil and its nanoemulsion modulate macrophage-mediated inflammatory responses and promote pressure ulcer healing.
Effect of Limosilactobacillus reuteri SBC5-3 Cell-free Supernatant on Growth Performance, Intestinal Inflammation, and Microbiota in Weaned Piglets Challenged With Enterotoxigenic Escherichia coli K88.
The 3D Genome Structure of a Blcap-Linked Silencer Loop Regulates Terminal Differentiation During Lens Fiber Cell Denucleation.
Allele-Specific Methylation Links Non-coding Variant of rs2280906 to MYOM2 Regulation in Schizophrenia.
FERMT1 suppresses the ferroptosis of glioma cells by interacting with MBOAT2.
MicroRNA-29b-3p promotes endothelial cell inflammation via NTRK2/PI3K/NLRP3 pathway in Moyamoya disease.
HIC2 suppresses glioblastoma progression via transcriptional repression of SEMA3A and inhibition of TGF-β signaling.
Epimedin B attenuates ovariectomy-induced bone loss by suppressing osteoclastogenesis through decreasing ROS production and targeting ESR1.
Inhibition of ALOX5-dependent ferroptosis by 6-C-methylquercetin: a potential therapeutic approach for alleviating rheumatoid arthritis.
Ezh2 Regulates Early Astrocyte Morphogenesis and Influences the Coverage of Astrocytic Endfeet on the Vasculature.
Stroke-Homing Peptide-DNase1 Alleviates Intestinal Ischemia Reperfusion Injury by Selectively Degrading Neutrophil Extracellular Traps.
Ferroptosis promotes 5-aminolevulinate acid-based photodynamic therapy in cervical cancer.
Sequential simulation of regeneration-specific microenvironments using scaffolds loaded with nanoplatelet vesicles enhances bone regeneration.
ASPM Induces Radiotherapy Resistance by Disrupting Microtubule Stability Leading to Chromosome Malsegregation in Non-Small Cell Lung Cancer.
Berberine Enhances the Sensitivity of Colorectal Cancer Cells to 5-FU Through Smoothing Endoplasmic Reticulum Stress-Mediated Autophagic Flux.
Andrographolide Attenuates Myocardial Ischemia-Reperfusion Injury in Mice by Up-Regulating PPAR-α.
Inhibition of GDNF-Driven Macrophage-to-Myofibroblast Transition Protects Against Colitis-Associated Intestinal Fibrosis.
Quorum Sensing Molecule Autoinducer-2 Promotes Macrophage Classical Polarization and Exacerbates Periodontal Inflammation Via Nf-Κb Signalling.
Inhibition of FKBP5 Alleviates Inflammation and Intestinal Barrier Dysfunction in Sepsis.
Combining network pharmacology and RNA sequencing to reveal the mechanism of emodin for the treatment of human neuroblastoma.
Protection of Dipsacoside B Against Cerebral Ischemia/Reperfusion Injury via Activating PINK1/Parkin-Mediated Mitophagy.
A multifunctional hydrogel system with synergistic effects against Staphylococcus aureus infections and inflammation in perioperative cataract surgery.
BMSCs-targeting piezoelectric stimulation and immunomodulatory dual-functional hydrogel for promoting diabetic bone regeneration.
Dissolvable microneedle-assisted transdermal administration of diacerein nanoparticles achieved satisfactory therapeutic effects in tendon-bone insertion repair by reducing oxidative stress and inflammation.
Homeobox C6 is Up-Regulated and Affects the Pathogenesis of Endometriosis.
Zika virus capsid protein impairs neural differentiation.
A Decoy Oligodeoxynucleotides Disturbing Forkhead Box O3 Mediated ctnna2 Transcriptional Repression Prevents Postoperative Neurocognitive Disorder in Mice.
Multifunctional targeted nanosystem based on aggregation-induced emission: Enhanced synergistic mild-photothermal chemotherapy of prostate cancer via downregulation of heat shock protein 70 under NIR-II imaging.
Schwann cells transplantation improves nerve injury and alleviates neuropathic pain in rats.
A tumor microenvironment-responsive nanocomposite for enhanced copper retention and hypoxia reversal to promote cuproptosis in tumor treatment.
Hypoxia-induced phenotypic transformation of scleral fibroblasts promotes activation of the adhesion patch pathway through paracrine effects leading to choroidal damage.
Proprotein convertase subtilisin/kexin type 9 contributes to cisplatin-induced acute kidney injury by interacting with cyclase-associated protein 1 to promote megalin lysosomal degradation.
Protective effect of micheliolide against inflammation and oxidative stress in asthma through the MAPK/NF-κB signalling pathway.
Cold exposure promotes the progression of osteoarthritis through downregulating APOE in cartilage.
Single cell RNA-sequencing reveals BHLHE40 and NDRG1 as key regulatory molecules modulating the trophoblastic senescence in preeclampsia.
Short-Chain Fatty Acids Promote Follicular Development by Alleviating Oxidative Stress-Induced Granulosa Cells Apoptosis in Sows.
Curcumin Promotes the Recovery of Motor Function After Brachial Plexus Avulsion Injury in Rats.
Rapid discovery of drug-introduced multiple organ dysfunction via NIR-II fluorescent imaging.
Suppressing neuroinflammation by Shenfu injection against ischemic stroke in mice via inhibiting RAGE-PI3K-Akt pathway.
Naringenin Accelerates Diabetic Wound Healing via Regulating Macrophage M2 Polarization and Efferocytosis.
The mechanism by which MALAT1/CREG1 regulates premature rupture of fetal membrane through autophagy mediated differentiation of amniotic fibroblasts.
Multiple omics-based machine learning reveals specific macrophage sub-clusters in renal ischemia-reperfusion injury and constructs predictive models for transplant outcomes.
Newcastle disease virus induces degradation of folliculin to regulate host cell energy metabolism and facilitate viral replication.
Macrophagic Ym1 orchestrates γδT cell-derived IL-17 production and keratinocyte functionality to mediate psoriasis-like skin inflammation.
SD49-7 attenuates cardiac hypertrophy by upregulation of S100B through KDM4A inhibition.
ZC3H13 mediates N6-methyladenosine modification of SNTB1 to promote epithelial-mesenchymal transition in gastric cancer.
Camellia japonica Flower Extract and the Active Constituent Hyperoside Repair DNA Damage Through FUNDC1-Mediated Mitophagy Pathway for Skin Anti-Aging.
Integrating network pharmacology and experimental validation to explore the mechanism of Yiqi Ziyin in treating immune thrombocytopenia.
Inhibition of UCH-L1 enhances immunotherapy efficacy in triple-negative breast cancer by stabilizing PD-L1.
Garlic-Derived Allicin Attenuates Parkinson's Disease via PKA/p-CREB/BDNF/DAT Pathway Activation and Apoptotic Inhibition.
RPN1 Is Associated With Immunosuppression in Pan-Cancer and Affects the Malignant Phenotype of Tumor.
Inflammation Inhibits HECTD1-Mediated AURKA Ubiquitination to Cause Extracellular Matrix Degradation in Osteoarthritis via Enhancing Cap-Dependent mRNA Translation of ADAMTS12.
USP44 Regulates Chemoresistance Induced by ROS and the MAPK/NF-κB Pathway Through the Stabilization of ITGB4 in Gastric Cancer.
Galnt4 Knockdown Modulates Lysosomal Function to Reduce Foam Cell Formation and Attenuate Atherosclerotic Plaque Progression.
METTL11A serves as a novel therapeutic target for acute myeloid leukemia through regulation of the p38-MAPK pathway.
PPARα deletion induces depressive-like behaviors by impairing neuronal synaptic plasticity and transmission.
Non-SMC condensin I complex subunit H promotes cell proliferation and inhibits cell apoptosis of clear cell renal cell carcinoma by activating the PI3K/AKT pathway.
Production of Fc-fused receptor agonists for glucagon-like peptide-1/glucose-dependent insulinotropic polypeptide (GLP-1/GIP) in the milk of transgenic mice.
Shaoyao Gancao decoction promotes splenic immune homeostasis mediating cGAS-STING signaling pathway to delay autoimmune hepatitis progression.
Qingxie Fuzheng granules attenuate cancer cachexia by restoring gut microbiota homeostasis and suppressing IL-6/NF-κB signaling in colorectal adenocarcinoma.
Exosomes derived from umbilical cord mesenchymal stem cells alleviate jaw bone marrow mesenchymal stem cells senescence and restore osteogenic differentiation potential.
5-HT(2a)R contributes to pulmonary arterial hypertension by modulating the AHR pathway.
Effect of the DPP4 Inhibitor Sitagliptin on Ferroptosis in Epilepsy.
MS4A6A/Ms4a6d deficiency disrupts neuroprotective microglia functions and promotes inflammation in Alzheimer's disease model.
Bleomycin promotes cellular senescence and activation of the cGAS-STING pathway without direct effect on fibrosis in an idiopathic pulmonary fibrosis model.
A novel SOX6 + melanoma cell subtype promotes early microsatellite invasion in Asian acral melanoma through fatty acid transport disorder.
The study of JAZF1-mediated apoptosis of decidual stromal cells by activating the NF-κB signaling pathway in spontaneous preterm birth.
CircCRIM1 promotes the translation of HIF-1α protein through its interaction with PTBP3 and enhances malignant progression and angiogenesis in glioblastoma.
Hybrid-Ligand Metal-Organic Frameworks Enabling Radio-Radiodynamic-Chemodynamic Therapy Primes Checkpoint Blockade Immunotherapy in Hypoxic Tumors.
L-arginine synergistic with 5-fluorouracil intervenes in DNA damage repair via the DNA-PKcs/ATM/ATR pathway in hepatocellular carcinoma cells.
Advanced glycation end products induce inflammaging in periodontal ligament fibroblasts through RAGE/AKT/mTOR/glycolysis pathway.
LncRNA938/ TAF9/TTK axis promotes EMT and serves as a therapeutic target in hepatoblastoma.
Targeting TSPAN1 promotes ferroptosis in endometrial cancer cells, reduces energy metabolism and inhibits malignant behavior.
Erianin induces GSDMD-dependent pyroptosis and synergistically enhances doxorubicin efficacy via the PI3K/AKT signaling pathway in diffuse large B-cell lymphoma.
Gut-resident Phascolarctobacterium succinatutens decreases fat accumulation via MYC-driven epigenetic regulation of arginine biosynthesis.
Structure-based drug design of small molecule AKT1 inhibitors to treat glioma.
CX26 promotes pancreatic cancer progression by competitively inhibiting interaction of c-Myc with PSMD2 and enhancing c-Myc stability.
Targeting ATF4-DDIT4/TXNIP induced mitochondrial dysfunction and ferroptosis: ISRIB as novel therapy for septic cardiomyopathy.
HIIT and MICT mitigate endothelial dysfunction in early atherosclerotic mice via PCSK9 inhibition.
WDR26-related Skraban-Deardorff syndrome: clinical, genetic and pathomechanistic insights.
Targeting HMGCS2: Ketogenesis Suppression Accelerates NAFLD Progression in T2DM Comorbidity, While Cynaroside Ameliorates NASH in Concomitant T2DM.
NDUFB9 ameliorates CUMS-induced depression-like behavior by promoting mitophagy.
Comparisons of miRNA profiles of exosomes derived from human iPSCs, ADSCs, and BMSCs and effects on chondrocyte function.
Selenoprotein K-dependent MyD88 palmitoylation promotes hepatic metaflammation in high-fat diet fed mice.
A novel prognostic risk score associated with resistance to docetaxel chemotherapy for predicting biochemical recurrence-free survival in patients with prostate cancer.
Proteomics profiling reveals the potential targets of Apatinib inhibiting the proliferation of glioma U251 cell.
Succinate accumulation induces pyroptosis and mitochondrial damage via the inhibition of ATP5F1D in HUVECs.
RIPK3-MLKL dependent necroptosis mediates depressive-like behavior by facilitating neuroinflammation.
Oroxin A suppresses colorectal tumor growth by regulating the TRIM24-mediated ferroptosis and TSPO pathway.
Cancer cell SPOCD1 promotes colorectal cancer liver metastasis by activating the CXCL12/CXCR4 signaling pathway in cancer-associated fibroblasts.
Indoleamine 2,3-dioxygenase can improve ovarian function in premature ovarian insufficiency via aromatic hydrocarbon receptor and regulatory T cells†.
NAT10 Mediates Cardiac Fibrosis Induced by Myocardial Infarction Through ac4C Modification of TGFBR1 mRNA.
Cathepsin D promotes acute myeloid leukemia progression through stabilization of the anti-apoptotic proteins.
miRNA-204-5p acts as a tumor suppressor in gastric cancer by inhibiting cell migration, invasion, and glycolysis via the RAB22A/PI3K/AKT axis.
Ergosterol from edible fungi: Enhancing fatty acid oxidation via CPT1A to protect against diabetic kidney disease.
Effects of Cholesterol Metabolism on Corneal Endothelial Dysfunction in Patients With Type 1 Diabetes.
Celastrol Activates SIRT1/PGC-1α/Nrf2 Axis to Inhibit Oxidative Damage for Subconjunctival Fibrosis Alleviation.
hUC-MSC-derived extracellular vesicles protect lung tissue from cigarette smoke-induced injury by upregulating the METTL3-mediated m(6)A modification.
Excision repair cross complementation group 1 gene exon 3 skipping isoform presents selective cGAS-STING activation in platinum-sensitive lung adenocarcinoma.
MSC-derived exosomes alleviate oxidative stress-induced lysosomal membrane permeabilization damage in degenerated nucleus pulposus cells via promoting m6A demethylation of Nrf2.
MOSPD1 facilitates fatty acid metabolism and gastric cancer progression by promoting the MAPK pathway.
Dental pulp stem cells derived exosomes inhibit ferroptosis via regulating the Nrf2-keap1/GPX4 signaling pathway to ameliorate chronic kidney disease injury.
Functional anti-inflammatory mesoporous silica nanoplatform for Synergistic and Targeted abdominal aortic aneurysm treatment.
Mechanisms of Differential Sensitivity to Ethanol-Induced Apoptosis in Mouse Spinal Cord at Different Developmental Stages-Akt/GSK Signaling and BAX.
Porcine epidemic diarrhea virus nsp14 inhibited IFN-Ⅰ production by targeting RIG-I for degradation.
Engineered brain-targeting exosome for reprogramming immunosuppressive microenvironment of glioblastoma.
Autophagy Regulation Attenuates Neuroinflammation and Cognitive Decline in an Alzheimer's Disease Mouse Model with Chronic Cerebral Hypoperfusion.
Copper doped bioactive glass promotes matrix vesicles-mediated biomineralization via osteoblast mitophagy and mitochondrial dynamics during bone regeneration.
Electroacupuncture at 5/100 Hz alleviates neuropathic pain in rats by inhibiting the CCL3/CCR5 axis in the spinal cord.
Olfactory mucosa mesenchymal stem cell-derived exosomes protect against neuroinflammation after subarachnoid hemorrhage by activating mitophagy.
Inhibition of Lactate Accumulation via USP38-Mediated MCT1 Deubiquitination Activates AKT/mTOR Signaling to Mitigate PM2.5-Induced Lung Injury.
Exploring the Mechanism of Kai-Xin-San to Improve Cognitive Deficits in AD Rats Induced by D-Gal and Aβ(25-35) Based on Multi-Omics and Network Analysis.
Heliox alleviates ischemia-reperfusion-induced damage to neuronal cells by repressing the USP46-SNX5 Axis-triggered ferroptosis.
miR-484 as an "OncomiR" in Breast Cancer Promotes Tumorigenesis by Suppressing Apoptosis Genes.
Self-propelling intelligent nanomotor: A dual-action photothermal and starvation strategy for targeted deep tumor destruction.
Functional poly(ether-ketone-ketone) composite scaffold with enhanced cell-material interaction, anti-inflammatory and osteogenesis for facilitating osteointegration and bone regeneration.
Molecular characterization of AMP-activated protein kinase (AMPK) α1/α2 from Cyprinus carpio and its roles in glucolipid metabolism and immune response.
Hyaluronic acid-functionalized nanoparticles enable enhanced chemo/chemodynamic therapy for the targeted treatment of colon cancer.
Sagittaria sagittifolia polysaccharide extract regulates Nrf2 to improve endoplasmic reticulum stress-mediated apoptosis in rat cataracts and HLEB3 cells.
Molecular mechanisms of antiproliferative and pro-apoptotic effects of essential oil active constituents in MCF7 and T24 cancer cell lines: in vitro insights and in silico modelling of proapoptotic gene product-compound interactions.
TNFAIP3-interacting protein 1 (ABIN-1) negatively regulates caspase-8/FADD-dependent pyroptosis.
IRX5 Promoted SREBP1-Mediated de Novo Fatty Acid Synthesis via HMGN4 in Hepatocellular Carcinoma.
Integrating network pharmacology and experimental validation to explore the potential mechanism by which resveratrol acts on osimertinib resistance in lung cancer.
Multifunctional porous organic polymer-based hybrid nanoparticles for sonodynamically enhanced cuproptosis and synergistic tumor therapy.
Cardiomyocyte-specific long noncoding RNA Trdn-as induces mitochondrial calcium overload by promoting the m(6)A modification of calsequestrin 2 in diabetic cardiomyopathy.
Screening bioactive compounds from Qianghuo (Notopterygium incisum) volatile oil via COX-2 magnetic ligand fishing.
Banxia Xiexin Decoction inhibits colitis-associated colorectal cancer development by modulating STAT3 signaling and gut microbiota.
Design, synthesis and antitumor activity evaluation of novel modified 18β-glycyrrhetinate derivatives as PPARγ agonists.
EGCG inhibits tobacco smoke-promoted proliferation of lung cancer cells through targeting CCL5.
5-hydroxymethylfurfural attenuates osteoarthritis by upregulating of glucose metabolism in chondrocytes.
Dual role of Baimao-Longdan-Congrong-Fang in inhibiting Staphylococcus aureus virulence factors and regulating TNF-α/TNFR1/NF-κB/MMP9 axis.
3-Hydroxypropionaldehyde modulates tryptophan metabolism to activate AhR signaling and alleviate ethanol-induced liver injury.
Bovine fecal extracellular vesicles: A novel noninvasive tool for understanding gut physiology and pathophysiology in calves.
WIPF1 regulates stemness in small cell lung cancer.
Fermented Cordyceps Powder alleviates silica-induced inflammation and fibrosis by inhibiting M1 macrophage polarization via the HMGB1-TLR4-NF-κB pathway.
Shuxuetong injection inhibits pyroptosis in acute ischemic stroke via CD44/NLRP3/GSDMD signal.
Ethyl acetate extract from Herpetospermun cardigerum wall. Ameliorated concanavalin A-induced autoimmune hepatitis in mice by reprofiling gut microenvironment to modulate IDO1/KYN and PI3K/AKT/NF-κB pathways.
Dihydromyricetin alleviates ETEC K88-induced intestinal inflammatory injury by inhibiting quorum sensing-related virulence factors.
ELK4 induced upregulation of HOMER3 promotes the proliferation and metastasis in glioma via Wnt/β-catenin/EMT signaling pathway.
The Antioxidant Effect of Selenium Is Enhanced by Cortisol Through Nrf2 Pathway in Bovine Endometrial Epithelial Cells.
Inhibition of Hepatoblastoma by Ganoderma Lucidum Polysaccharide via the Induction of HDAC4-p16-RB Axis-Mediated Cellular Senescence.
Targeting the liquid-liquid phase separation of nucleocapsid broadly inhibits the replication of SARS-CoV-2 strains.
Targeting UAF1 Alleviate Neurotoxicity by Inhibiting APP/NLRP3 Axis-Mediated Pyroptosis and Apoptosis.
Analysis of Stratifin Expression and Proteome Variation in a Rat Model of Acute Lung Injury.
Acoustic Enrichment Prevents Early Life Stress-Induced Disruptions in Sound Azimuth Processing.
F-box protein FBXO32 ubiquitinates and stabilizes D-type cyclins to drive cancer progression.
LncRNA-5829: a novel inhibitor of cardiac fibrosis.
Hydrogen Sulfide (H(2)S) Mitigates Sepsis-Induced Adrenal Dysfunction via Inhibition of TNFα-Mediated Necroptosis.
Enterohemorrhagic Escherichia coli O157:H7 Infection Inhibits Host Endoplasmic Reticulum Stress in Intestinal Epithelial Cells via the PERK Pathway.
Ginsenoside CK modulates glucose metabolism via PPARγ to ameliorate SCOP-induced cognitive dysfunction.
The IL-6 autocrine loop promoting IFN-γ-induced fibroblast senescence is involved in psychological stress-mediated exacerbation of vitiligo.
PKA plays a conserved role in regulating gene expression and metabolic adaptation by phosphorylating Rpd3/HDAC1.
Targeting prominin-2/BACH1/GLS pathway to inhibit oxidative stress-induced ferroptosis of bone mesenchymal stem cells.
Streptococcus mutans-derived extracellular vesicles promote skin wound healing via tRNA cargo.
PYK2 promotes cell proliferation and epithelial-mesenchymal transition in endometriosis by phosphorylating Snail1.
Synergistic Antioxidant and Anti-Ferroptosis Therapy via BPNS-Encapsulated Thermoresponsive Chitosan Hydrogel for Spinal Cord Injury Regeneration.
RNA-coupled CRISPR Screens Reveal ZNF207 as a Regulator of LMNA Aberrant Splicing in Progeria.
Unveiling the multifaceted benefits of Simiao Pill in ulcerative colitis: Integrative analysis of signaling pathways, gut microbiota, and lipid metabolism.
Regulation of monocyte polarization through nuclear factor Kappa B /inhibitor of Kappa B Alpha pathway by Cuscuta chinensis Lam. In postmenopausal osteoporosis.
TAK-242 attenuates NLRP3-ASC inflammasome-mediated neuroinflammation via TLR4/NF-κB pathway in rat experimental autoimmune neuritis.
Kanglexin attenuates spinal cord injury by modulating pyroptosis and polarization via the PKA/NF-κB signaling pathway.
Ilex latifolia Improves the Anti-Tumor Effectiveness of Rapamycin Against Breast Cancer In Vitro and In Vivo.
Antiviral Activity of 1-Deoxynojirimycin Extracts of Mulberry Leaves Against Porcine Epidemic Diarrhea Virus.
SWI/SNF complex-mediated ZNF410 cooperative binding maintains chromatin accessibility and enhancer activity.
Dual Disruption of EGFR/PI3K Signaling: IGF2BP2 Targeting Reverses Anti-EGFR Resistance in CAFs-Infiltrated Oral Squamous Cell Carcinoma.
Orthodontic treatment after occlusal intervention balances osteoblast and osteoclast differentiation via SIRT1 beta catenin signaling in rats with hypofunctional occlusion.
MicroRNA-30a-3p Influences Milk Fat Metabolism by Targeting PTEN in Mammary Epithelial Cells of Sheep.
CD147 regulates the Rap1 signaling pathway to promote proliferation, migration, and invasion, and inhibit apoptosis in colorectal cancer cells.
S100A9 as a promising therapeutic target for diabetic foot ulcers.
Hydrogen sulfide improves poststroke depression-induced inflammation in microglial cells by enhancing endoplasmic reticulum autophagy and inhibiting the cGAS-STING pathway.
Y4 RNA fragment alleviates myocardial injury in heart transplantation via SNRNP200 to enhance IL-10 mRNA splicing.
P4HA1 is highly expressed in gastric cancer and promotes proliferation and metastasis of gastric cancer cells.
PDZK1 inhibits MRP2-mediated oxaliplatin chemosensitivity in hepatocellular carcinoma.
RAGE deficiency ameliorates abdominal aortic aneurysm progression.
PRC1 as an independent adverse prognostic factor in Wilms tumor via integrated bioinformatics and experimental validation.
Green Tea Ameliorates Depression-Like Behavior and Cognitive Impairment Induced by High-Fat Diet and Chronic Mild Stress.
Wogonoside ameliorates oxidative damage in tubular epithelial cells of diabetic nephropathy by modulating the HNF4A-NRF2 axis.
Oleanolic acid inhibits mesangial cell proliferation and inflammatory response in mesangial proliferative glomerulonephritis through IL-17/ERK/AKT pathway.
UBTF facilitates acute myeloid leukemia development and immune escape via PD-L1 regulation.
TLR4-mediated endoplasmic reticulum stress regulates pyroptosis in macrophages infected with the Bacillus Calmette-Guérin mycobacterial.
The interaction between IL-33 and TRIM28 in the regulation of macrophage polarization in an ST2-independent manner.
GPR37L1 identifies spinal cord astrocytes and protects neuropathic pain after nerve injury.
Discovery of Airway-Administered Ionophores for Mn(2+) to Mitigate Lung Metastasis by Targeting Disseminated Tumor Cell.
Total ginsenosides from wild ginseng improve immune regulation in a rat model of spleen qi deficiency by modulating fecal-bacteria-associated short-chain fatty acids and intestinal barrier integrity.
Aberrant expression of TRIM44, transcriptionally regulated by KLF9, contributes to the process of diabetic retinopathy.
CDC25A inhibition sensitizes melanoma cells to doxorubicin and NK cell therapy.
Silicate-based therapy for inflammatory dilated cardiomyopathy by inhibiting the vicious cycle of immune inflammation via FOXO signaling.
Tannic acid‑cerium nanoenzymes serve as broad-spectrum antioxidants to alleviate acute kidney injury by modulating macrophage polarization, mitophagy and endoplasmic reticulum stress.
5-Aminolevulinic Acid: A Novel Approach to Improving Radioresistance in Prostate Cancer.
Expression Distribution of Keratins in Normal and Pathological Corneas and the Regulatory Role of Krt17 on Limbal Stem Cells.
Triclosan exposure induces liver fibrosis in mice: The heterogeneous nuclear ribonucleoprotein A1/pyruvate kinase M2 axis drives hepatic stellate cell activation.
REGγ deficiency ameliorates hepatic ischemia and reperfusion injury in a mitochondrial p66shc dependent manner in mice.
Tanshinone IIA alleviates IL-1β-induced chondrocyte apoptosis and inflammation by regulating FBXO11 expression.
Activable Photodynamic DNA Probe with an "AND" Logic Gate for Precision Skin Cancer Therapy.
B-Type Natriuretic Peptide Inhibits the Expression and Function of SERCA2a in Heart Failure.
Deoxycholic acid aggravates necrotizing enterocolitis through downregulation of mesenchymal-epithelial transition factor expression.
Isoliquiritigenin Suppresses Breast Tumor Development by Enhancing Host Antitumor Immunity.
Astragaloside I from Astragalus Attenuates Diabetic Kidney Disease by Regulating HDAC3/Klotho/TGF-β1 Loop.
Therapeutic Potential of Danyankang Capsule in High-Fat Diet-Induced Cholelithiasis and Its Impact on Liver FXR Signaling and Gut Microbiota.
IL13RA2 promotes progression of infantile haemangioma by activating glycolysis and the Wnt/β-catenin signaling pathway.
Integrative bioinformatics and in vitro exploration of EVI2A expression: unraveling its immunological and prognostic implications in kidney renal clear cell carcinoma.
Leukemia Inhibitory Factor Protects against Degeneration of Cone Photoreceptors Caused by RPE65 Deficiency.
Custom-Made Ce-Mn Bimetallic Nanozyme for the Treatment of Intervertebral Disc Degeneration by Inhibiting Oxidative Stress and Modulating Macrophage M1/M2 Polarization.
Cadmium-induced annulus fibrosus cell senescence contributes to intervertebral disc degeneration via the JNK/p53 signaling pathway.
The Mechanism of Action and Experimental Verification of Narenmandula in the Treatment of Postmenopausal Osteoporosis.
mirna-383-5p Functions as an Anti-oncogene in Glioma through the Akt/mTOR Signaling Pathway by Targeting VEGFA.
CAPN5 attenuates cigarette smoke extract-induced apoptosis and inflammation in BEAS-2B cells.
N-cadherin Alleviates Apoptosis and Senescence of Nucleus Pulposus Cells via Suppressing ROS-dependent ERS in the Hyper-osmolarity Microenvironment.
Aortic calcification accelerates cardiac dysfunction via inducing apoptosis of cardiomyocytes.
Resveratrol Mitigates Uremic Toxin-Induced Intestinal Barrier Dysfunction in Chronic Kidney Disease by Promoting Mitophagy and Inhibiting Apoptosis Pathways.
Attenuation of palmitic acid-induced lysyl oxidase overexpression in the ovary contributes to the improvement of ovulation in obesity by metformin.
Shikonin Induces Autophagy and Apoptosis in Esophageal Cancer EC9706 Cells by Regulating the AMPK/mTOR/ULK Axis.
Role of the NOD1/Rip2 Signaling Pathway in Macrophage Inflammatory Activation Induced by ox-LDL.
Dietary Fiber-Derived Microbial Butyrate Suppresses ILC2-Dependent Airway Inflammation in COPD.
Mesenchymal Stem Cells Accelerate Recovery of Acetic Acid-Induced Chronic Gastric Ulcer by Regulating Ekt/Akt/TRIM29 Axis.
ITGA1 Promotes Glioma Cell Proliferation and Affects Immune Cell Infiltration in Low-Grade Glioma.
Exploring the Analgesic Initiation Mechanism of Tuina in the Dorsal Root Ganglion of Minor CCI Rats via the TRPV1/TRPA1-cGMP Pathway.
HMGB1 Modulates High Glucose-Induced Erroneous Differentiation of Tendon Stem/Progenitor Cells through RAGE/β-Catenin Pathway.
The m6A modification-mediated positive feedback between glycolytic lncRNA SLC2A1-DT and c-Myc promotes tumorigenesis of hepatocellular carcinoma.
Sirtuin 4 (Sirt4) downregulation contributes to chondrocyte senescence and osteoarthritis via mediating mitochondrial dysfunction.
IKBKE regulates renal cell carcinoma progression and sunitinib resistance through the RRM2-AKT pathway.
HSPD1 Supports Osteosarcoma Progression through Stabilizing ATP5A1 and thus Activation of AKT/mTOR Signaling.
KIF15 promotes human glioblastoma progression under the synergistic transactivation of REST and P300.
Dual role of CD73 as a signaling molecule and adenosine-generating enzyme in colorectal cancer progression and immune evasion.
RETRACTED: Curcumin alleviates osteoarthritis in mice by suppressing osteoclastogenesis in subchondral bone via inhibiting NF-κB/JNK signaling pathway.
Mesoporous zinc-polyphenol nanozyme for attenuating renal ischemia-reperfusion injury.
miR-328-3p targets TLR2 to ameliorate oxygen-glucose deprivation injury and neutrophil extracellular trap formation in HUVECs via inhibition of the NF-κB signaling pathway.
Circular RNA circ-CARD8 regulates alveolar macrophage pyroptosis through the miR-580-3p/CARD8 pathway in acute lung injury.
GLP-1RA improves diabetic renal injury by alleviating glomerular endothelial cells pyrotosis via RXRα/circ8411/miR-23a-5p/ABCA1 pathway.
ADAR1 plays a protective role in proximal tubular cells under high glucose conditions by attenuating the PI3K/AKT/mTOR signaling pathway.
Therapeutic Effects of Lifei Decoction in a Murine Model of COPD Induced by LPS and Cigarette Smoke.
Novel L-(CaP-ZnP)/SA Nanocomposite Hydrogel with Dual Anti-Inflammatory and Mineralization Effects for Efficient Vital Pulp Therapy.
Localized Administration of Bcar3 siRNA via Nano-Self-Assembly to Treat Idiopathic Pulmonary Fibrosis by Disrupting Macrophage-Fibroblast Crosstalk.
Cigarette Smoke Extract Induces MUC5AC Expression Through the ROS/ IP3R/Ca(2+) Pathway in Calu-3 Cells.
Pretreatment of Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes with Quercetin Enhances the Healing of Diabetic Skin Wounds by Modulating Host-Microbiota Interactions.
16S rRNA Gene Sequencing Combined with Metabolomics to Explore Intestinal Flora and Metabolic Changes in Young Febrile Rats and the Mechanism of Xiangqin Jiere Granules.
Imperatorin Suppresses Aberrant Hedgehog Pathway and Overcomes Smoothened Antagonist Resistance via STAT3 Inhibition.
Obacunone Alleviates Inflammatory Pain by Promoting M2 Microglial Polarization and by Activating Nrf2/HO-1 Signaling Pathway.
Cholinergic Anti-inflammatory Pathway Attenuates Acute Liver Failure Through Inhibiting MAdCAM1/α4β7-mediated Gut-derived Proinflammatory Lymphocytes Accumulation.
Ube2L6 Promotes M1 Macrophage Polarization in High-Fat Diet-Fed Obese Mice via ISGylation of STAT1 to Trigger STAT1 Activation.
Regulation of Inflammation, Lipid Metabolism, and Liver Fibrosis by Core Genes of M1 Macrophages in NASH.
A Neutrophil Extracellular Traps-Related Gene Trait Revealed the Prospective Therapy Strategy of Coronary Atherosclerosis.
Arctiin Alleviates Atopic Dermatitis Against Inflammation and Pyroptosis Through Suppressing TLR4/MyD88/NF-κB and NLRP3/Caspase-1/GSDMD Signaling Pathways.
MicroRNA-204-5p Ameliorates Renal Injury via Regulating Keap1/Nrf2 Pathway in Diabetic Kidney Disease.
Claudin-2 Mediates the Proximal Tubular Epithelial Cell-Fibroblast Crosstalk via Paracrine CTGF.
Angiotensin-(1-7) Modulates the Warburg Effect to Alleviate Inflammation in LPS-Induced Macrophages and Septic Mice.
Network Pharmacology-Based Strategy to Explore the Effect and Mechanism of Zhizhu Granule Improving Glucose-Lipid Metabolism in Rats with Metabolic Syndrome.
Expression Analysis of VPS72 and Associated Biological Behaviors in Colon Cancer.
High expression of COPZ2 is associated with poor prognosis and cancer progression in glioma.
Quercetin Protects Against Global Cerebral ischemia‒reperfusion Injury by Inhibiting Microglial Activation and Polarization.
Methyl Cinnamate (MC) Alleviates Free Fatty Acids (FFAs) Induced Lipid Accumulation Through the AMPK Pathway in HepG2 Cells.
Identification of Macrophage-Related Biomarkers for Abdominal Aortic Aneurysm Through Combined Single-Cell Sequencing and Machine Learning.
Cistanche deserticola polysaccharide alleviates constipation by regulating intestinal barrier function and intestinal microbiota and their metabolites.
THSR Mediated MiR374b Targeting C/EBP β/FOXO1 to Accelerate Thyroid Stimulating Hormone-Induced Hepatic Steatosis.
Identification and experimental validation of ferroptosis-related gene lactotransferrin in age-related hearing loss.
SP1 Mediated PIK3CB Upregulation Promotes Gastric Carcinogenesis.
Synergistic Anti-Tumor Efficacy Achieved by Reversing Drug Resistance through the Regulation of the Tumor Immune Microenvironment with IL-12 and Osimertinib Combination Therapy.
ACOX2 Serves as a Favorable Indicator Related to Lipid Metabolism and Oxidative Stress for Biochemical Recurrence in Prostate Cancer.
High expression of malic enzyme 1 predicts adverse prognosis in patients with cytogenetically normal acute myeloid leukaemia and promotes leukaemogenesis through the IL-6/JAK2/STAT3 pathways.
Inhibition of the MyD88 signaling pathway could upregulates Ghrelin expression to synergistically regulate hepatic Echinococcus multilocularis-infected progression.
Yishen paidu pills attenuates 5/6 nephrectomy induced kidney disease via inhibiting the PI3K/AKT/mTOR signaling pathway.
ATP5J regulates microglial activation via mitochondrial dysfunction, exacerbating neuroinflammation in intracerebral hemorrhage.
Green carbon dots derived from Zingiberis Rhizoma Carbonisatum alleviate ovalbumin-induced allergic rhinitis.
Shikonin suppresses proliferation of osteosarcoma cells by inducing ferroptosis through promoting Nrf2 ubiquitination and inhibiting the xCT/GPX4 regulatory axis.
Molecular targets and mechanisms of Sijunzi decoction in the treatment of Parkinson's disease: evidence from network pharmacology, molecular docking, molecular dynamics simulation, and experimental validation.
MiR-130c-5p targets the SHVV n gene and upregulates immune cytokines (IL-6, IL-22, IL-1β) to inhibit viral replication.
Hyperbaric oxygen-induced acute lung injury: A mouse model study on pathogenic characteristics and recovery dynamics.
KAE ameliorates LPS-mediated acute lung injury by inhibiting PANoptosis through the intracellular DNA-cGAS-STING axis.
Astrocyte-derived exosomal miR-378a-5p mitigates cerebral ischemic neuroinflammation by modulating NLRP3-mediated pyroptosis.
Comprehensive analysis of lactylation-related gene sets and mitochondrial functions in gastric adenocarcinoma: implications for prognosis and therapeutic strategies.
Gasdermin D could be lost in the brain parenchyma infarct core and a pyroptosis-autophagy inhibition effect of Jie-Du-Huo-Xue decoction after stroke.
RAB42 overexpression correlates with poor prognosis, immune cell infiltration and chemoresistance.
The clinical significance and anti-tumor role of PRKG1 in bladder cancer.
YTHDC1 Regulates the Migration, Invasion, Proliferation, and Apoptosis of Rheumatoid Fibroblast-Like Synoviocytes.
Integrated bioinformatics analysis of nucleotide metabolism based molecular subtyping and biomarkers in lung adenocarcinoma.
Kumujan B suppresses TNF-α-induced inflammatory response and alleviates experimental colitis in mice.
Identification of potential nucleomodulins of Mycoplasma bovis by direct biotinylation and proximity-based biotinylation approaches.
A dicoumarol-graphene oxide quantum dot polymer inhibits porcine reproductive and respiratory syndrome virus through the JAK-STAT signaling pathway.
Pulsatilla decoction alleviates DSS-induced UC by activating FXR-ASBT pathways to ameliorate disordered bile acids homeostasis.
Exhausted signature and regulatory network of NK cells in myasthenia gravis.
The mechanism of low molecular weight fucoidan-incorporated nanofiber scaffolds inhibiting oral leukoplakia via SR-A/Wnt signal axis.
Involvement of autophagy in mesaconitine-induced neurotoxicity in HT22 cells revealed through integrated transcriptomic, proteomic, and m6A epitranscriptomic profiling.
L-arginine combination with 5-fluorouracil inhibit hepatocellular carcinoma cells through suppressing iNOS/NO/AKT-mediated glycolysis.
FTO diversely influences sensitivity of neuroblastoma cells to various chemotherapeutic drugs.
Anti-neuroinflammatory effect of hydroxytyrosol: a potential strategy for anti-depressant development.
Lithocarpus polystachyus Rehd. ameliorates cerebral ischemia/reperfusion injury through inhibiting PI3K/AKT/NF-κB pathway and regulating NLRP3-mediated pyroptosis.
Celastrol alleviates diabetic vascular injury via Keap1/Nrf2-mediated anti-inflammation.
Alteration in the number, morphology, function, and metabolism of erythrocytes in high-altitude polycythemia.
Dl-3-n-butylphthalide attenuates cerebral ischemia/reperfusion injury in mice through AMPK-mediated mitochondrial fusion.
Identification of immune-related endoplasmic reticulum stress genes in proliferative diabetic retinopathy using bioinformatics analysis.
PCMT1 confirmed as a pan-cancer immune biomarker and a contributor to breast cancer metastasis.
Evaluation of specific binding of [(11)C]TZ7774 to the receptor-interacting protein kinase 1 (RIPK1) in the brain.
Construction of gastric cancer prognostic signature based on the E26 transcription factor and the identification of novel oncogene ELK3.
Integrated analysis of lactate-related genes identifies POLRMT as a novel marker promoting the proliferation, migration and energy metabolism of hepatocellular carcinoma via Wnt/β-Catenin signaling.
A multidimensional analysis of ZW10 interacting kinetochore protein in human tumors.
Targeting NANOS1 in triple-negative breast cancer: synergistic effects of digoxin and PD-1 inhibitors in modulating the tumor immune microenvironment.
Identification of key programmed cell death genes for predicting prognosis and treatment sensitivity in colorectal cancer.
TurboID-mediated proximity labeling technologies to identify virus co-receptors.
Identification and validation of three diagnostic autophagy-related genes associated with advanced plaques and immune cell infiltration in carotid atherosclerosis based on integrated bioinformatics analyses.
Lysyl oxidase-like 1 predicts the prognosis of patients with primary glioblastoma and promotes tumor invasion via EMT pathway.
Molecular dynamics of chemotactic signalling orchestrates dental pulp stem cell fibrosis during aging.
Formononetin promotes porcine oocytes maturation and improves embryonic development by reducing oxidative stress.
Antibacterial and antioxidant phlorizin-loaded nanofiber film effectively promotes the healing of burn wounds.
PRNP is a pan-cancer prognostic and immunity-related to EMT in colorectal cancer.
PCSK9 inhibitor alleviates experimental pulmonary fibrosis-induced pulmonary hypertension via attenuating epithelial-mesenchymal transition by suppressing Wnt/β-catenin signaling in vivo and in vitro.
High-fat diet mouse model receiving L-glucose supplementations propagates liver injury.
Resveratrol promotes cholesterol efflux from dendritic cells and controls costimulation and T-cell activation in high-fat and lipopolysaccharide-driven atherosclerotic mice.
Supplementation of Ampelopsis grossedentata extract contributes to the improvement of intestinal health in swine.
Do extracellular vesicles have specific target cells?; Extracellular vesicle mediated embryo maternal communication.
Clcn3 deficiency ameliorates high-fat diet-induced obesity and improves metabolism in mice.
Stauntonia chinensis injection relieves neuropathic pain by increasing the expression of PSD-95 and reducing the proliferation of phagocytic microglia.
Expression Characteristics, Immune Signature, and Prognostic Value of the SOCS Family Identified by Multiomics Integrative Analysis in Liver Cancer.
The mechanical regulatory role of ATP13a3 in osteogenic differentiation of pre-osteoblasts.
ASIC1/RIP1 accelerates atherosclerosis via disrupting lipophagy.
Study on the mechanisms of defective spermatogenesis induced by TiO(2) NPs based on 3D blood-testis barrier microfluidic chip.
Intervention of Asprosin Attenuates Oxidative Stress and Neointima Formation in Vascular Injury.
PFKP is upregulated in 5-fluorouracil-resistant patients and suppresses the antitumor activity of 5-fluorouracil in colorectal cancer in vitro and in vivo.
Shikonin and chitosan-silver nanoparticles synergize against triple-negative breast cancer through RIPK3-triggered necroptotic immunogenic cell death.
HSPB8 attenuates lipopolysaccharide‑mediated acute lung injury in A549 cells by activating mitophagy.
Netrin‑4 promotes VE‑cadherin expression in endothelial cells through the NF‑κB signaling pathway.
UBE2C regulates the KEAP1/NRF2 signaling pathway to promote the growth of gastric cancer by inhibiting autophagy.
Fucoidan alleviates doxorubicin-induced cardiotoxicity by inhibiting ferroptosis via Nrf2/GPX4 pathway.
A proton channel, Otopetrin 1 (OTOP1) is N-glycosylated at two asparagine residues in third extracellular loop.
STING1-accelerated vascular smooth muscle cell senescence-associated vascular calcification in diabetes is ameliorated by oleoylethanolamide via improved mitochondrial DNA oxidative damage.
A new insight into the mechanism of dichlorodiphenyltrichloroethane-induced hepatotoxicity based on GSDME-mediated pyroptosis.
Lactobacillus gasseri ATCC33323 affects the intestinal mucosal barrier to ameliorate DSS-induced colitis through the NR1I3-mediated regulation of E-cadherin.
Identification of inflammatory response-related molecular mechanisms based on the ATM/ATR/p53 pathway in tumor cells.
Cinnamaldehyde protects SH-SY5Y cells against advanced glycation end-products induced ectopic cell cycle re-entry.
Nasal solitary chemosensory cells govern daily rhythm in mouse model of allergic rhinitis.
Repression of BRD4 mitigates NLRP3 inflammasome-mediated pyroptosis in Mycobacterium-infected macrophages by repressing endoplasmic reticulum stress.
Involucrasin B suppresses airway inflammation in obese asthma by inhibiting the TLR4-NF-κB-NLRP3 pathway.
The role of α7nAchR and PD-L1 in neuroimmune regulation of keloid treatment.
HDAC8 Enhances the Function of HIF-2α by Deacetylating ETS1 to Decrease the Sensitivity of TKIs in ccRCC.
The interlacing anticancer effect of pharmacologic ascorbate, chloroquine, and resveratrol.
Exosomes derived from mesenchymal stem cells ameliorate impaired glucose metabolism in myocardial Ischemia/reperfusion injury through miR-132-3p/PTEN/AKT pathway.
miR-155 induces sepsis-associated damage to the intestinal mucosal barrier via sirtuin 1/nuclear factor-κB-mediated intestinal pyroptosis.
Rab8a/SNARE complex activation promotes vesicle anchoring and transport in spinal astrocytes to drive neuropathic pain.
Mechanistic investigation of wogonin in delaying the progression of endothelial mesenchymal transition by targeting the TGF-β1 pathway in pulmonary hypertension.
Forskolin is an effective therapeutic small molecule for the treatment of hypertrophic cardiomyopathy through ADCY6/cAMP/PKA pathway.
Fluoride induces immunotoxicity by regulating riboflavin transport and metabolism partly through IL-17A in the spleen.
Sortilin-mediated translocation of mitochondrial ACSL1 impairs adipocyte thermogenesis and energy expenditure in male mice.
Vitamin D receptor alleviates lipid peroxidation in diabetic nephropathy by regulating ACLY/Nrf2/Keap1 pathway.
LncRNA PVT1 induces mitochondrial dysfunction of podocytes via TRIM56 in diabetic kidney disease.
Targeting G6PD to mitigate cartilage inflammation in TMJOA: The NOX4-ROS-MAPK axis as a therapeutic avenue.
Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation.
SOST/Sclerostin impairs the osteogenesis and angiogesis in glucocorticoid-associated osteonecrosis of femoral head.
Diminished expression of the ubiquitin-proteasome system in early treatment-naïve patients with rheumatoid arthritis and concomitant type 2 diabetes may be linked to IL-1 pathway hyper-activity; results from PEAC cohort.
Role of β-adrenergic signaling and the NLRP3 inflammasome in chronic intermittent hypoxia-induced murine lung cancer progression.
Exercise training upregulates CD55 to suppress complement-mediated synaptic phagocytosis in Parkinson's disease.
Adaptive Differences in Cellular and Behavioral Responses to Circadian Disruption between C57BL/6 and BALB/c Strains.
LncRNA lncLLM Facilitates Lipid Deposition by Promoting the Ubiquitination of MYH9 in Chicken LMH Cells.
Single-cell dissection of the human blood-brain barrier and glioma blood-tumor barrier.
Rice Husk Silica Liquid Enhances Autophagy and Reduces Overactive Immune Responses via TLR-7 Signaling in Lupus-Prone Models.
CircPOLA2 sensitizes non-small cell lung cancer cells to ferroptosis and suppresses tumorigenesis via the Merlin-YAP signaling pathway.
Mesenchymal stem cells in tumor microenvironment: drivers of bladder cancer progression through mitochondrial dynamics and energy production.
Duck hepatitis A virus utilizes PCBP2 to facilitate viral translation and replication.
Mandarin fish von Hippel-Lindau protein regulates the NF-κB signaling pathway via interaction with IκB to promote fish ranavirus replication.
Palliative effect of rotating magnetic field on glucocorticoid-induced osteonecrosis of the femoral head in rats by regulating osteoblast differentiation.
Glucose attenuates the long-term adverse neurodevelopment effect of neonate pain stimulus via CRF/GR in rats.
HSV-1 immune escapes in microglia by down-regulating GM130 to inhibit TLR3-mediated innate immune responses.
Inhibiting Soluble Epoxide Hydrolase Suppresses NF-κB p65 Signaling and Reduces CXCL10 Expression as a Potential Therapeutic Target in Hashimoto's Thyroiditis.
Exosome miRNA profile and mitigating effect of miR-23a-3p/Cul3 axis on apoptosis in the pathogenesis of SiO(2) dust-induced lung fibrosis.
Mitigating lead-induced osteoporosis: The role of butyrate in gut-bone axis restoration.
Integrating metagenomics with metabolomics for gut microbiota and metabolites profiling in acute pancreatitis.
DMDD, isolated from Averrhoa carambola L., ameliorates diabetic nephropathy by regulating endoplasmic reticulum stress-autophagy crosstalk.
Alkaloids of Aconiti Lateralis Radix Praeparata inhibit growth of non-small cell lung cancer by regulating PI3K/Akt-mTOR signaling and glycolysis.
Kidney targeting and modulating macrophage polarization through AMPK signaling: Therapeutic mechanism of berberine in uric acid nephropathy.
Alleviation effects of dexmedetomidine on myocardial ischemia/reperfusion injury through fatty acid metabolism pathway via Elovl6.
Neuronal ferroptosis and ferroptosis-mediated endoplasmic reticulum stress: Implications in cognitive dysfunction induced by chronic intermittent hypoxia in mice.
β-Caryophyllene mitigates ischemic stroke-induced white matter lesions by inhibiting pyroptosis.
Glucose influences endometrial receptivity to embryo implantation through O-GlcNAcylation-mediated regulation of the cytoskeleton.
LRP1 facilitates hepatic glycogenesis by improving the insulin signaling pathway in HFD-fed mice.
Promotion of DNA end resection by BRCA1-BARD1 in homologous recombination.
Angelica sinensis polysaccharides promote extramedullary stress erythropoiesis via ameliorating splenic glycolysis and EPO/STAT5 signaling-regulated macrophages.
Mechanism of Treadmill Exercise Combined with Rich Environmental Stimulation to Improve Depression in Post-stroke Depression Model Rats.
Ellagic acid improves osteoarthritis by inhibiting PGE2 production in M1 macrophages via targeting PTGS2.
Golgi protein ACBD3 downregulation sensitizes cells to ferroptosis.
Groenlandicine enhances cisplatin sensitivity in cisplatin-resistant osteosarcoma cells through the BAX/Bcl-2/Caspase-9/Caspase-3 pathway.
Quercetin Regulates Microglia M1/M2 Polarization and Alleviates Retinal Inflammation via ERK/STAT3 Pathway.
A novel small-molecule PCSK9 inhibitor E28362 ameliorates hyperlipidemia and atherosclerosis.
GFPT2 expression is induced by gemcitabine administration and enhances invasion by activating the hexosamine biosynthetic pathway in pancreatic cancer.
ADSC-derived exosomes provide neuroprotection in sepsis-associated encephalopathy by regulating hippocampal pyroptosis.
USP14 promotes the cancer stem-like cell properties of OSCC via promoting SOX2 deubiquitination.
Duck plague virus-encoded microRNA dev-miR-D28-3p inhibits viral replication via targeting UL27.
Emodin induces ferroptosis in colorectal cancer through NCOA4-mediated ferritinophagy and NF-κb pathway inactivation.
Vitamin D inhibits ferroptosis and mitigates the kidney injury of prediabetic mice by activating the Klotho/p53 signaling pathway.
Validation of quercetin in the treatment of colon cancer with diabetes via network pharmacology, molecular dynamics simulations, and in vitro experiments.
Dihydroartemisinin inhibits ATP6 activity, reduces energy metabolism of hepatocellular carcinoma cells, promotes apoptosis and inhibits metastasis via CANX.
Mitogen-activated protein kinase kinase kinase 1 facilitates the temozolomide resistance and migration of GBM via the MEK/ERK signalling.
Small nucleolar RNA host gene 5 plays a role in orthodontic tooth movement by inhibiting osteoclast differentiation.
Identification and Verification of Key Genes Associated with Temozolomide Resistance in Glioblastoma Based on Comprehensive Bioinformatics Analysis.
Oncoprotein-induced transcript 3 protein-enriched extracellular vesicles promotes NLRP3 ubiquitination to alleviate acute lung injury after cardiac surgery.
The protective role of quercetin against copper-induced female reproductive toxicity: Insights from transcriptome analysis.
Combined effects of TiO(2) nanoparticle and fipronil co-exposure on microbiota in mouse intestine.
Procyanidine alleviates bisphenol A-induced apoptosis in TM3 cells via the Nrf2 signaling pathway.
AMPK induces PIAS3 mediated SUMOylation of E3 ubiquitin ligase Smurf1 impairing osteogenic differentiation and traumatic heterotopic ossification.
EREG silencing inhibits tumorigenesis via inactivating ERK/p38 MAPK pathway in pancreatic ductal adenocarcinoma.
HIF-1 induced tiRNA-Lys-CTT-003 is protective against cisplatin induced ferroptosis of renal tubular cells in mouse AKI model.
Ghrelin is involved in regulating the progression of Echinococcus Granulosus-infected liver lesions through suppression of immunoinflammation and fibrosis.
Seno-antigen-pulsed dendritic cell vaccine induce anti-aging immunity to improve adipose tissue senescence and metabolic abnormalities.
Effects of exogenous hydrogen sulfide and honokiol intervention on the proliferation, apoptosis, and calcium signaling pathway of rat enteric glial cells.
Mechanisms of Shufeng Jiedu Capsule in treating bacterial pneumonia based on network pharmacology and experimental verification.
Xianling Lianxia formula improves the efficacy of trastuzumab by enhancing NK cell-mediated ADCC in HER2-positive BC.
Jiawei Buzhong Yiqi Decoction attenuates polycystic ovary syndrome through regulating kisspeptin-GPR54-AKT-SHBG system.
Gastrodin exerts perioperative myocardial protection by improving mitophagy through the PINK1/Parkin pathway to reduce myocardial ischemia-reperfusion injury.
The MEF2A/SNHG16/miR-425-5p/NOTCH2 axis induces gemcitabine resistance by inhibiting ferroptosis in the starving bladder tumor microenvironment.
Endothelial Cells Mediated by STING Regulate Oligodendrogenesis and Myelination During Brain Development.
Single-cell dissection reveals promotive role of ENO1 in leukemia stem cell self-renewal and chemoresistance in acute myeloid leukemia.
Aldo-keto reductase family 1 member C3 mediates radioresistance of esophageal cancer cells through suppressing MAPK and AKT signaling.
Characterizations of Protein Arginine Deiminase 1 as a Substrate of NTMT1: Implications of Nα-Methylation in Protein Stability and Interaction.
Characteristics of Myocardial Structure and Central Carbon Metabolism during the Early and Compensatory Stages of Cardiac Hypertrophy.
Advanced paternal age exacerbates neuroinflammation in offspring via m6A modification-mediated intergenerational inheritance.
PYGL regulation of glycolysis and apoptosis in glioma cells under hypoxic conditions via HIF1α-dependent mechanisms.
Bioinformatics analysis reveals SOD1 is a prognostic factor in lung adenocarcinoma.
PAIP1 binds to pre-mRNA and regulates alternative splicing of cancer pathway genes including VEGFA.
Diagnostic and prognostic significance of tetraspanin 6 and its role in facilitating glioma progression.
Rapid increase of MFGE8 secretion from endometrial epithelial cells is an indicator of extracellular vesicle mediated embryo maternal dialogue.
Erjingpill bionic cerebrospinal fluid alleviates LPS-induced inflammatory response in BV2 cells by inhibiting glycolysis via mTOR.
The pro-tumor activity of INTS7 on lung adenocarcinoma via inhibiting immune infiltration and activating p38MAPK pathway.
Morin alleviates DSS-induced ulcerative colitis in mice via inhibition of inflammation and modulation of intestinal microbiota.
Virtual Screening, Molecular Dynamics, and Mechanism Study of Homeodomain-Interacting Protein Kinase 2 Inhibitor in Renal Fibroblasts.
Macrophage NRF1 promotes mitochondrial protein turnover via the ubiquitin proteasome system to limit mitochondrial stress and inflammation.
Ketone Esters Partially and Selectively Rescue Mitochondrial Bioenergetics After Acute Cervical Spinal Cord Injury in Rats: A Time-Course.
GLP-1R activation attenuates the progression of pulmonary fibrosis via disrupting NLRP3 inflammasome/PFKFB3-driven glycolysis interaction and histone lactylation.
Tetramethylpyrazine Analogue T-006 Protects Neuronal and Endothelial Cells Against Oxidative Stress via PI3K/AKT/mTOR and Nrf2 Signaling.
Impact of polystyrene nanoplastics on apoptosis and inflammation in zebrafish larvae: Insights from reactive oxygen species perspective.
Nasal instillation of polystyrene nanoplastics induce lung injury via mitochondrial DNA release and activation of the cyclic GMP-AMP synthase-stimulator of interferon genes-signaling cascade.
Astragaloside I Promotes Lipophagy and Mitochondrial Biogenesis to Improve Hyperlipidemia by Regulating Akt/mTOR/TFEB Pathway.
Regorafenib promotes antitumor progression in melanoma by reducing RRM2.
MIR194-2HG, a miRNA host gene activated by HNF4A, inhibits gastric cancer by regulating microRNA biogenesis.
Neutrophil N1 polarization induced by cardiomyocyte-derived extracellular vesicle miR-9-5p aggravates myocardial ischemia/reperfusion injury.
Micro RNA-175 Targets Claudin-1 to Inhibit Madin-Darby Canine Kidney Cell Adhesion.
Overexpression of USP35 enhances the protective effect of hUC-MSCs and their extracellular vesicles in oxygen-glucose deprivation/reperfusion-induced SH-SY5Y cells via stabilizing FUNDC1.
Potential involvement of connective tissue growth factor in chondrocytes apoptosis of Kashin-Beck disease.
The Application of Duck Embryonic Fibroblasts CCL-141 as a Cell Model for Adipogenesis.
Daucosterol alleviates heart failure with preserved ejection fraction through activating PPARα pathway.
NF-κB pathway activation by Octopus peptide hydrolysate ameliorates gut dysbiosis and enhances immune response in cyclophosphamide-induced mice.
zMAP toolset: model-based analysis of large-scale proteomic data via a variance stabilizing z-transformation.
Preliminary study of the role of histone deacetylase (HDAC) in steroid-induced avascular necrosis of the femoral head induced by BMSC adipogenic differentiation.
Chromatin Licensing and DNA Replication Factor 1 (CDT1) Is a Potential Prognostic Biomarker Involved in the Malignant Biological Behavior of Glioma.
Investigating PPT2's role in ovarian cancer prognosis and immunotherapy outcomes.
Enhanced interactions within microenvironment accelerates dismal prognosis in HBV-related HCC after TACE.
The reduction of imidazole propionate induced by intermittent fasting promotes recovery of peripheral nerve injury by enhancing migration of Schwann cells.
Lipoxin A4 modulates the PKA/CREB and NF-κB signaling pathway to mitigate chondrocyte catabolism and apoptosis in temporomandibular joint osteoarthritis.
The role of ALDH1A1 in glioblastoma proliferation and invasion.
Peripheral dopamine suppression and elevated cystatin C in early diabetic nephropathy in spontaneously diabetic rats.
Endoplasmic reticulum stress promotes oxidative stress, inflammation, and apoptosis: A novel mechanism of citrinin-induced renal injury and dysfunction.
Apoptosis mediated by crosstalk between mitochondria and endoplasmic reticulum: A possible cause of citrinin disruption of the intestinal barrier.
Modulation of choline and lactate metabolism by basic fibroblast growth factor mitigates neuroinflammation in type 2 diabetes: Insights from (1)H-NMR metabolomics analysis.
Mitochondrial calcium uniporter knockdown in hippocampal neurons alleviates anxious and depressive behavior in the 3XTG Alzheimer's disease mouse model.
Isoliquiritigenin alleviates cerebral ischemia-reperfusion injury by reducing oxidative stress and ameliorating mitochondrial dysfunction via activating the Nrf2 pathway.
Serum exosomal miRNA promote glioma progression by targeting SOS1 via abscopal effect of radiation.
Stratifin (SFN) Regulates Cervical Cancer Cell Proliferation, Apoptosis, and Cytoskeletal Remodeling and Metastasis Progression Through LIMK2/Cofilin Signaling.
Hyperoxia can Induce Lung Injury by Upregulating AECII Autophagy and Apoptosis Via the mTOR Pathway.
An interpretable artificial intelligence framework for designing synthetic lethality-based anti-cancer combination therapies.
Quercetin inhibits endothelial & hepatocellular carcinoma cell crosstalk via reducing extracellular vesicle-mediated VEGFR2 mRNA transfer.
ELMO1 regulates macrophage directed migration and attenuates inflammation via NF-κB signaling pathway in primary biliary cholangitis.
PM(10) dysregulates epithelial barrier function in human corneal epithelial cells that is restored by antioxidant SKQ1.
Inhibition of BCAT1 expression improves recurrent miscarriage by regulating cellular dysfunction and inflammation of trophoblasts.
SPAG4 enhances mitochondrial respiration and aerobic glycolysis in colorectal cancer cells by activating the PI3K/Akt signaling pathway.
Ruscogenin Exerts Anxiolytic-Like Effect via Microglial NF-κB/MAPKs/NLRP3 Signaling Pathways in Mouse Model of Chronic Inflammatory Pain.
Albumin-based co-loaded sonosensitizer and STING agonist nanodelivery system for enhanced sonodynamic and immune combination antitumor therapy.
PI3K/AKT/mTORC1 signalling pathway regulates MMP9 gene activation via transcription factor NF-κB in mammary epithelial cells of dairy cows.
N6-methyladenosine RNA methylation modification regulates the transcription of viral-derived E (XSR) miRNAs to promote ALV-J replication.
Data-mining-based biomarker evaluation and experimental validation of SHTN1 for bladder cancer.
PI4KB is an essential host factor for duck hepatitis a virus 1 replication and translation.
Methacrylated hyaluronic acid/laponite photosensitive, sustained-release hydrogel loaded with bilobalide for enhancing random flap survival through mitigation of endoplasmic reticulum stress.
Intra-articular injection of platinum nanozyme-loaded silk fibroin/pullulan hydrogels relieves osteoarthritis through ROS scavenging and ferroptosis suppression.
Structural insights into human zinc transporter ZnT1 mediated Zn(2+) efflux.
Activation of BK channels prevents diabetes-induced osteopenia by regulating mitochondrial Ca(2+) and SLC25A5/ANT2-PINK1-PRKN-mediated mitophagy.
Mechanism of Gastrodin against neurotoxicity based on network pharmacology, molecular docking and experimental verification.
TMT-based proteomics reveals methylprotodioscin alleviates oxidative stress and inflammation via COX6C in myocardial infraction.
Vitamin U alleviates AFB(1)-induced hepatotoxicity in pregnant and lactating mice by regulating the Nrf2/Hmox1 pathway.
Akt inhibitors prevent CyHV-2 infection in vitro.
A comparative study on the immune response in the head and trunk kidney of yellow catfish infected with Edwardsiella ictaluri.
Melanin resistance of heat-processed ginsenosides from Panax ginseng berry treated with citric acid through autophagy pathway.
GBF1 deficiency causes cataracts in human and mouse.
Matrix metalloproteinase-11 regulates inverted papilloma epithelial cell migration and invasion.
Tetrahedral Framework Nucleic Acid-Based Delivery of Astaxanthin Suppresses Chondrocyte Pyroptosis and Modulates Oxidative Stress for the Treatment of Osteoarthritis.
Erbin alleviates sepsis-induced cardiomyopathy by inhibiting RIPK1-dependent necroptosis through activating PKA/CREB pathway.
METTL3 -mediated m6A modification of circ_0000620 regulates cisplatin sensitivity and apoptosis in lung adenocarcinoma via the MiR-216b-5p/KRAS axis.
Bifidobacterium pseudolongum-Derived Bile Acid from Dietary Carvacrol and Thymol Supplementation Attenuates Colitis via cGMP-PKG-mTORC1 Pathway.
The gut microbial metabolite indole-3-aldehyde alleviates impaired intestinal development by promoting intestinal stem cell expansion in weaned piglets.
Engineered Hybrid Lantibiotic that Selectively Combats Infections Caused by Staphylococcus aureus.
S-ketamine alleviates depression-like behavior and hippocampal neuroplasticity in the offspring of mice that experience prenatal stress.
Sensing steroid hormone 17α-hydroxypregnenolone by GPR56 enables protection from ferroptosis-induced liver injury.
The ZNF263/CPT1B axis regulates fatty acid β-oxidation to affect cisplatin resistance in lung adenocarcinoma.
Naringin Alleviates Intestinal Fibrosis by Inhibiting ER Stress-Induced PAR2 Activation.
GATA1-activated lncRNA OIP5-AS1 and GAS5 promote pyroptosis to exacerbate asthma through regulating miR-136-5p/LIFR axis.
Tumor Protein D53 (TPD53): Involvement in Malignant Transformation of Low-Malignant Oral Squamous Cell Carcinoma Cells.
CAFs-derived lactate enhances the cancer stemness through inhibiting the MST1 ubiquitination degradation in OSCC.
Spatially organized tumor-stroma boundary determines the efficacy of immunotherapy in colorectal cancer patients.
Trehalose Alleviates D-Galactose-Induced Aging-Related Granulosa Cell Death in Ovaries.
Bovine NMRAL2 Protein Blunts Nitric Oxide Production and Inflammatory Response in Mycobacterium bovis Infected Bovine Lung Epithelial Cells.
Gastrodin attenuates diabetic cardiomyopathy characterized by myocardial fibrosis by inhibiting the KLK8-PAR1 signaling axis.
Hyperoside induces ferroptosis in chronic myeloid leukemia cells by targeting NRF2.
Ficolin-1 ameliorates pulmonary fibrosis via directly binding to TGF-β1.
The Hydrophobic Amino Acid-Rich Fish Collagen Peptide Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice via Repairing the Intestinal Barrier, Regulating Intestinal Flora and AA Metabolism.
The effect of paeoniflorin on the rewarding effect of methamphetamine and the associated cognitive impairment in mice.
The Regulatory Effect of Insulin-Like Growth Factor-2 on Hypothalamic Gonadotropin-Releasing Hormone Neurons during the Pubertal Period.
Identifying genetic targets in clinical subtypes of Parkinson's disease for optimizing pharmacological treatment strategies.
Lentivirus-mediated Knockdown of Ski Improves Neurological Function After Spinal Cord Injury in Rats.
Investigating the mechanism of ferroptosis induction by sappanone A in hepatocellular carcinoma: NRF2/xCT/GPX4 axis.
EHD1 promotes breast cancer metastasis through upregulating HIF2a expression via activating mTOR pathway.
Single-cell sequencing combined with transcriptomics and in vivo and in vitro analysis reveals the landscape of ferroptosis in myocardial ischemia-reperfusion injury.
Hippocampal cannabinoid type 2 receptor alleviates chronic neuropathic pain-induced cognitive impairment via microglial DUSP6 pathway in rats.
D-glucaro-1,4-lactone improves Diethylnitrosamine induced hepatocellular carcinoma in rats via the uric acid-ROS pathway.
The protective role of Cordyceps cicadae and its active ingredient myriocin against sodium iodate-induced age-related macular degeneration via an anti-necroptotic TNF-RIPK1/3 pathway.
Human monocyte-derived macrophages shift subcellular metalloprotease activity depending on their activation state.
Effect of exercise during pregnancy on offspring development through ameliorating high glucose and hypoxia in gestational diabetes mellitus.
Gastrodin against oxidative stress-inflammation crosstalk via inhibiting mtDNA/TLR9 and JAK2/STAT3 signaling to ameliorate ischemic stroke injury.
HIF-1α knockdown attenuates phenotypic transformation and oxidative stress induced by high salt in human aortic vascular smooth muscle cells.
High-intensity interval training and moderate-intensity continuous training alleviate vascular dysfunction in spontaneously hypertensive rats through the inhibition of pyroptosis.
Taraxerone inhibits M1 polarization and alleviates sepsis-induced acute lung injury by activating SIRT1.
Glial maturation factor-β deficiency prevents oestrogen deficiency-induced bone loss by remodelling the actin network to suppress adipogenesis of bone marrow mesenchymal stem cells.
FXR deficiency induced ferroptosis via modulation of the CBP-dependent p53 acetylation to suppress breast cancer growth and metastasis.
The role of CISD1 reduction in macrophages in promoting COPD development through M1 polarization and mitochondrial dysfunction.
Improvement of osteogenic differentiation potential of placenta-derived mesenchymal stem cells by metformin via AMPK pathway activation.
LncRNA GClnc1 promotes osteosarcoma progression by stabilizing NONO and blocking FBXW7-mediated ubiquitination.
TIPE2 aggravates experimental colitis and disrupts intestinal epithelial barrier integrity by activating JAK2/STAT3/SOCS3 signal pathway.
Aerobic exercise modulates RIPK1-mediated MAP3K5/JNK and NF-κB pathways to suppress microglia activation and neuroinflammation in the hippocampus of D-gal-induced accelerated aging mice.
Hepatocyte-derived Fetuin-A promotes alcohol-associated liver disease in mice by inhibiting autophagy-lysosome degradation of TLR and M2 macrophage polarization.
Protective effects of a novel bicyclic γ-butyrolactone compound against H(2)O(2) or corticosterone-induced neural cell apoptosis.
Hydrogen sulfide upregulates SIRT1 to inhibit ox-HDL-induced endothelial cell damage and mitochondrial dysfunction.
Luteolin prevents cadmium-induced PC12 cell death by suppressing the Akt/mTOR signaling pathway.
Itaconate inhibits corticosterone-induced necroptosis and neuroinflammation via up-regulating menin in HT22 cells.
TRIM29 facilitates gemcitabine resistance via MEK/ERK pathway and is modulated by circRPS29/miR-770-5p axis in PDAC.
Stevioside Ameliorates Palmitic Acid-Induced Abnormal Glucose Uptake via the PDK4/AMPK/TBC1D1 Pathway in C2C12 Myotubes.
Glutaminase potentiates the glycolysis in esophageal squamous cell carcinoma by interacting with PDK1.
Elevated serum levels of leukocyte cell-derived chemotaxin 2 are associated with the prevalence of metabolic syndrome.
Mogroside Ⅴ Inhibits M1 Polarization and Inflammation of Diabetic Mouse Macrophages via p38 MAPK/NF-Κb Signaling Pathway.
Tetrahydrobiopterin (BH(4)) treatment stabilizes tyrosine hydroxylase: Rescue of tyrosine hydroxylase deficiency phenotypes in human neurons and in a knock-in mouse model.
Epigallocatechin gallate alleviated the in vivo toxicity of ZnO nanoparticles to mouse intestine.
Exosomal lncRNA XIST promotes perineural invasion of pancreatic cancer cells via miR-211-5p/GDNF.
Bakuchiol regulates TLR4/MyD88/NF-κB and Keap1/Nrf2/HO-1 pathways to protect against LPS-induced acute lung injury in vitro and in vivo.
Suppression of long noncoding RNA SNHG6 alleviates cigarette smoke-induced lung inflammation by modulating NF-κB signaling.
Compensatory upregulation of MT2A alleviates neurogenic intermittent claudication through inhibiting activated p38 MAPK-mediated neuronal apoptosis.
Lacosamide alleviates bilateral cavernous nerve injury-induced erectile dysfunction in the rat model by ameliorating pathological changes in the corpus cavernosum.
Joint Analysis of Genome-wide DNA Methylation and Transcription Sequencing Identifies the Role of BAX Gene in Heat Stress-Induced-Sertoli Cells Apoptosis.
Synaptic vesicle protein 2A mitigates parthanatos via apoptosis-inducing factor in a rat model of pharmacoresistant epilepsy.
Macrophage M2 polarization promotes pulpal inflammation resolution during orthodontic tooth movement.
Prognostic and immunotherapeutic implications of bilirubin metabolism-associated genes in lung adenocarcinoma.
Transcriptome analysis and functional verification reveal the roles of copper in resistance to potato virus Y infection in tobacco.
Regulation of Glucose Metabolism for Cell Energy Supply In Situ via High-Energy Intermediate Fructose Hydrogels.
Metal-Organic Framework-Mediated Synergistic Hypoxia-Activated Chemo-Immunotherapy Induced by High Intensity Focused Ultrasound for Enhanced Cancer Theranostics.
Endoplasmic reticulum stress-induced necroptosis promotes cochlear inflammation: Implications for age-related hearing loss.
Inhibition of piezo1 prevents chronic cerebral hypoperfusion-induced cognitive impairment and blood brain barrier disruption.
Iguratimod inhibits protein citrullination and inflammation by downregulating NBCe2 in patients with rheumatoid arthritis.
Epigallocatechin-3-gallate confers protection against myocardial ischemia/reperfusion injury by inhibiting ferroptosis, apoptosis, and autophagy via modulation of 14-3-3η.
Vascular endothelial glycocalyx shedding in ventilator-induced lung injury in rats.
Single cell RNA-sequencing reveals the cellular senescence of placental mesenchymal stem/stromal cell in preeclampsia.
Tiliroside disrupted iron homeostasis and induced ferroptosis via directly targeting calpain-2 in pancreatic cancer cells.
Development and Application of the CRISPR-dcas13d-eIF4G Translational Regulatory System to Inhibit Ferroptosis in Calcium Oxalate Crystal-Induced Kidney Injury.
Protective effects of sodium humate and its zinc and selenium chelate on the oxidative stress, inflammatory, and intestinal barrier damage of Salmonella Typhimurium-challenged broiler chickens.
MKP1 may be involved in the occurrence of depression by regulating hippocampal autophagy in rats.
D-mannose alleviates intervertebral disc degeneration through glutamine metabolism.
Blocking of FGFR4 signaling by F30 inhibits hepatocellular carcinoma cell proliferation through HMOX1-dependent ferroptosis pathway.
Naringenin reduces oxidative stress and necroptosis, apoptosis, and pyroptosis in random-pattern skin flaps by enhancing autophagy.
Ovarian PERK/NRF2/CX43/StAR/progesterone pathway activation mediates female reproductive dysfunction induced by cold exposure.
miR-4645-3p attenuates podocyte injury and mitochondrial dysfunction in diabetic kidney disease by targeting Cdk5.
FGF13 enhances the function of TRPV1 by stabilizing microtubules and regulates acute and chronic itch.
Transgenic female mice producing trans 10, cis 12-conjugated linoleic acid present excessive prostaglandin E2, adrenaline, corticosterone, glucagon, and FGF21.
EGCG suppresses PD-1 expression of T cells via inhibiting NF-κB phosphorylation and nuclear translocation.
Icariside I reduces breast cancer proliferation, apoptosis, invasion, and metastasis probably through inhibiting IL-6/STAT3 signaling pathway.
Comparative Proteomics Elucidates the Potential Mechanism of Sperm Capacitation of Chinese Mitten Crabs (Eriocheir sinensis).
Contrasting Impacts of Ubiquitin Overexpression on Arabidopsis Growth and Development.
Inhibition of lysosomal TRPML1 channel eliminates breast cancer stem cells by triggering ferroptosis.
Investigation of Uterine Fluid Extracellular Vesicles' Proteomic Profiles Provides Novel Diagnostic Biomarkers of Bovine Endometritis.
Improved Immunotherapy Outcomes via Cuproptosis Upregulation of HLA-DRA Expression: Promoting the Aggregation of CD4(+) and CD8(+)T Lymphocytes in Clear Cell Renal Cell Carcinoma.
Activation of Nrf2/HO-1 signaling pathway exacerbates cholestatic liver injury.
Water extract of moschus alleviates erastin-induced ferroptosis by regulating the Keap1/Nrf2 pathway in HT22 cells.
Integration of serum pharmacochemistry and metabolomics to reveal the underlying mechanism of shaoyao-gancao-fuzi decoction to ameliorate rheumatoid arthritis.
Shaoyao decoction improves damp-heat colitis by activating the AHR/IL-22/STAT3 pathway through tryptophan metabolism driven by gut microbiota.
Free total rhubarb anthraquinones protect intestinal mucosal barrier of SAP rats via inhibiting the NLRP3/caspase-1/GSDMD pyroptotic pathway.
An integrated network pharmacology, molecular docking and experiment validation study to investigate the potential mechanism of Isobavachalcone in the treatment of osteoarthritis.
HIV-1 with gag processing defects activates cGAS sensing.
Microglial CMPK2 promotes neuroinflammation and brain injury after ischemic stroke.
Targeting osteopontin alleviates endometriosis and inflammation by inhibiting the RhoA/ROS axis and achieves non-invasive in vitro detection via menstrual blood.
Effect of Akkermansia muciniphila on pancreatic islet β-cell function in rats with prediabetes mellitus induced by a high-fat diet.
Effect of total flavonoids of Dracocephalum moldavica L. On neuroinflammation in Alzheimer's disease model amyloid-β (Aβ1-42)-peptide-induced astrocyte activation.
HSP70 positively regulates translation by interacting with the IRES and stabilizes the viral structural proteins VP1 and VP3 to facilitate duck hepatitis A virus type 1 replication.
The acetylation of MDH1 and IDH1 is associated with energy metabolism in acute liver failure.
Resveratrol protects cardiomyocytes against ischemia/reperfusion-induced ferroptosis via inhibition of the VDAC1/GPX4 pathway.
Puerarin Delays Mammary Gland Aging by Regulating Gut Microbiota and Inhibiting the p38MAPK Signaling Pathway.
Cadmium exposure induced neuronal ferroptosis and cognitive deficits via the mtROS-ferritinophagy pathway.
Microcystin-RR promote lipid accumulation through CD36 mediated signal pathway and fatty acid uptake in HepG2 cells.
Pharmacodynamics and mechanism of Erigeron breviscapus granules in the treatment of ischemic stroke in mice by regulating sphingolipid metabolism based on metabolomics.
The changes of neurogenesis in the hippocampal dentate gyrus of SAMP8 mice and the effects of acupuncture and moxibustion.
Activin and Hepatocyte Growth Factor Promotes Colorectal Cancer Stemness and Metastasis through FOXM1/SOX2/CXCR4 Signaling.
High expression of SRSF1 facilitates osteosarcoma progression and unveils its potential mechanisms.
Regulation of cerebral blood flow boosts precise brain targeting of vinpocetine-derived ionizable-lipidoid nanoparticles.
Palmatine inhibits expression fat mass and obesity associated protein (FTO) and exhibits a curative effect in dextran sulfate sodium (DSS)-induced experimental colitis.
The Role of SLIT3-ROBO4 Signaling in Endoplasmic Reticulum Stress-Induced Delayed Corneal Epithelial and Nerve Regeneration.
DDX18 Facilitates the Tumorigenesis of Lung Adenocarcinoma by Promoting Cell Cycle Progression through the Upregulation of CDK4.
Cubic liquid crystals containing propolis flavonoids as in situ thermo-sensitive hydrogel depots for periodontitis treatment: Preparation, pharmacodynamics and therapeutic mechanisms.
Design, synthesis, and evaluation of formylpiperazine analogs of Ferrostatin-1 as novel improved ferroptosis inhibitors.
Mammalian STE20-like kinase 1 inhibits synoviocytes activation in rheumatoid arthritis through mitochondrial dysfunction mediated by SIRT3/mTOR axis.
Enhanced VEGF secretion and blood-brain barrier disruption: Radiation-mediated inhibition of astrocyte autophagy via PI3K-AKT pathway activation.
Knockdown of ANGPTL4 inhibits adipogenesis of preadipocyte via autophagy.
NLRP3 inflammasome mediates abnormal epithelial regeneration and distal lung remodeling in silica‑induced lung fibrosis.
14-3-3-η interacts with BCL-2 to protect human endothelial progenitor cells from ox-LDL-triggered damage.
BRMS1L confers anticancer activity in non-small cell lung cancer by transcriptionally inducing a redox imbalance in the GPX2-ROS pathway.
A potential mechanism clue to the periodic storm from microglia activation and progressive neuron damage induced by paraquat exposure.
D-pinitol alleviates diabetic cardiomyopathy by inhibiting the optineurin-mediated endoplasmic reticulum stress and glycophagy signaling pathway.
A combination of PD-L1-targeted IL-15 mRNA nanotherapy and ultrasound-targeted microbubble destruction for tumor immunotherapy.
Skin derived precursors induced Schwann cells mediated tissue engineering-aided neuroregeneration across sciatic nerve defect.
SADS-CoV nsp1 inhibits the STAT1 phosphorylation by promoting K11/K48-linked polyubiquitination of JAK1 and blocks the STAT1 acetylation by degrading CBP.
CD74-ROS1 L2026M mutant enhances autophagy through the MEK/ERK pathway to promote invasion, metastasis and crizotinib resistance in non-small cell lung cancer cells.
NDRG2 alleviates photoreceptor apoptosis by regulating the STAT3/TIMP3/MMP pathway in mice with retinal degenerative disease.
SIRT2-mediated deacetylation of ACLY promotes the progression of oesophageal squamous cell carcinoma.
OTUD7B knockdown inhibits the proliferation and stemness of breast cancer cells by destabilizing FOXM1.
Integrin β8 prevents pericyte-myofibroblast transition and renal fibrosis through inhibiting the TGF-β1/TGFBR1/Smad3 pathway in diabetic kidney disease.
Human RNA-binding protein HNRNPD interacts with and regulates the repair of deoxyribouridine in DNA.
VSIG4 inhibits RANKL-induced osteoclastogenesis by enhancing Nrf2-dependent antioxidant response against reactive oxygen species production.
Purification and structural characterization of two polysaccharides with anti-inflammatory activities from Plumbago zeylanica L.
Homoharringtonine induces apoptosis of mammary carcinoma cells by inhibiting the AKT/mTOR signaling pathway.
Bioactive monoterpenoids and acetophenones from the aerial parts of Eupatorium fortunei.
Alpha-ketoglutaric acid attenuates oxidative stress and modulates mitochondrial dynamics and autophagy of spleen in a piglet model of lipopolysaccharide-induced sepsis.
β-Sitosterol targets ASS1 for Nrf2 ubiquitin-dependent degradation, inducing ROS-mediated apoptosis via the PTEN/PI3K/AKT signaling pathway in ovarian cancer.
Baicalein ameliorates cognitive impairment of vascular dementia rats via suppressing neuroinflammation and regulating intestinal microbiota.
Luteolin ameliorates pentetrazole-induced seizures through the inhibition of the TLR4/NF-κB signaling pathway.
IGF2BP3-stabilized CAMK1 regulates the mitochondrial dynamics of renal tubule to alleviate diabetic nephropathy.
USP46 enhances tamoxifen resistance in breast cancer cells by stabilizing PTBP1 to facilitate glycolysis.
B-GOS alleviates olanzapine-induced lipid disturbances in mice by enriching Akkermansia and upregulation of PGRMC1-Wnt signaling.
Extracellular vesicle mediated targeting delivery of growth differentiation factor-15 improves myocardial repair by reprogramming macrophages post myocardial injury.
Possible pharmacological targets and mechanisms of sivelestat in protecting acute lung injury.
SETDB2 interacts with BUBR1 to induce accurate chromosome segregation independently of its histone methyltransferase activity.
Qingguang'an-induced autophagy in TFs inhibits scar formation: A follow-up in vivo mechanistic investigation.
EGLN3 attenuates gastric cancer cell malignant characteristics by inhibiting JMJD8/NF-κB signalling activation independent of hydroxylase activity.
Light-Enhanced Hypoxia-Responsive Gene Editing for Hypoxia-Resistant Photodynamic and Immunotherapy.
Endothelial cell-derived extracellular vesicles expressing surface VCAM1 promote sepsis-related acute lung injury by targeting and reprogramming monocytes.
METTL3-mediated m(6)A modification of SOX4 regulates osteoblast proliferation and differentiation via YTHDF3 recognition.
CAR-Aptamers Enable Traceless Enrichment and Monitoring of CAR-Positive Cells and Overcome Tumor Immune Escape.
PM(2.5) induces cardiac defects via AHR-SIRT1-PGC-1α mediated mitochondrial damage.
Artemisinin ameliorates cognitive decline by inhibiting hippocampal neuronal ferroptosis via Nrf2 activation in T2DM mice.
Macrophage-derived exosomal HMGB3 regulates silica-induced pulmonary inflammation by promoting M1 macrophage polarization and recruitment.
Apurinic/apyrimidinic endodeoxyribonuclease 1 (APE1) promotes stress granule formation via YBX1 phosphorylation in ovarian cancer.
Rutaecarpine protects podocytes in diabetic kidney disease by targeting VEGFR2/NLRP3-mediated pyroptosis.
Anti-diabetic mechanism and potential bioactive peptides of casein hydrolysates in STZ/HFD-induced diabetic rats.
Abscisic acid ameliorates d-galactose -induced aging in mice by modulating AMPK-SIRT1-p53 pathway and intestinal flora.
TXNIP/NLRP3 aggravates global cerebral ischemia-reperfusion injury-induced cognitive decline in mice.
Progesterone inhibits endometrial cancer growth by inhibiting glutamine metabolism through ASCT2.
Human Seminal Extracellular Vesicles Enhance Endometrial Receptivity Through Leukemia Inhibitory Factor.
Resveratrol ameliorates glioblastoma inflammatory response by reducing NLRP3 inflammasome activation through inhibition of the JAK2/STAT3 pathway.
Volatile oil of Angelica sinensis Radix improves cognitive function by inhibiting miR-301a-3p targeting Ppp2ca in cerebral ischemia mice.
Integrating transcriptomics and network pharmacology to reveal the mechanisms of total Rhizoma Coptidis alkaloids against nonalcoholic steatohepatitis.
The mechanism of Chebulae Fructus Immaturus promote diabetic wound healing based on network pharmacology and experimental verification.
Synergistic dual cell therapy for atherosclerosis regression: ROS-responsive Bio-liposomes co-loaded with Geniposide and Emodin.
Air-Liquid Interface Microfluidic Monitoring Sensor Platform for Studying Autophagy Regulation after PM2.5 Exposure.
The Effectiveness of Four Nicotinamide Adenine Dinucleotide (NAD(+)) Precursors in Alleviating the High-Glucose-Induced Damage to Hepatocytes in Megalobrama amblycephala: Evidence in NAD(+) Homeostasis, Sirt1/3 Activation, Redox Defense, Inflammatory Response, Apoptosis, and Glucose Metabolism.
Melatonin-Derived Carbon Dots with Free Radical Scavenging Property for Effective Periodontitis Treatment via the Nrf2/HO-1 Pathway.
Effects of latroeggtoxin-VI on dopamine and α-synuclein in PC12 cells and the implications for Parkinson's disease.
Construction of recombinant fluorescent LSDV for high-throughput screening of antiviral drugs.
Selenomethionine Alleviates Deoxynivalenol-Induced Oxidative Injury in Porcine Intestinal Epithelial Cells Independent of MAPK Pathway Regulation.
Glycyrrhizic acid restores the downregulated hepatic ACE2 signaling in the attenuation of mouse steatohepatitis.
ICBP90, an epigenetic regulator, induces DKK3 promoter methylation, promotes glioma progression, and reduces sensitivity to cis-platinum.
CircFOXO3 mediates hypoxia-induced autophagy of endometrial stromal cells in endometriosis.
Proteomic and molecular analyses to understand the promotive effect of safranal on soybean growth under salt stress.
NOP14 as a Potential Predictor of Adult-Type Diffuse Glioma Prognosis and Immunotherapy, is Related to Cell Migration, Proliferation, and CD8(+)T Cell Infiltration.
Rh proteins and H(+) transporters involved in ammonia excretion in Amur Ide (Leuciscus waleckii) under high alkali exposure.
Rare flavanone-diarylheptanoid hybrids from Typha angustifolia shows anti breast cancer activity via activating TGF-β1/Smad signaling pathway.
Cancer-associated fibroblast-secreted FGF7 as an ovarian cancer progression promoter.
Mitochondrial carrier homolog 2 increases malignant phenotype of human gastric epithelial cells and promotes proliferation, invasion, and migration of gastric cancer cells.
Epigallocatechin-3-gallate protects sepsis-induced myocardial dysfunction by inhibiting the nuclear factor-κB signaling pathway.
Targeting DEP domain containing 1 in anaplastic thyroid carcinoma: Implications for stemness regulation and malignant phenotype suppression.
Glutaredoxin-1 modulates the NF-κB signaling pathway to activate inducible nitric oxide synthase in experimental necrotizing enterocolitis.
MRE11A: a novel negative regulator of human DNA mismatch repair.
Obesity-induced downregulation of miR-192 exacerbates lipopolysaccharide-induced acute lung injury by promoting macrophage activation.
UCHL1 contributes to insensitivity to endocrine therapy in triple-negative breast cancer by deubiquitinating and stabilizing KLF5.
PSMB2 plays an oncogenic role in glioma and correlates to the immune microenvironment.
Solute carrier family 35 member A2 regulates mitophagy through the PI3K/AKT/mTOR axis, promoting the proliferation, migration, and invasion of osteosarcoma cells.
Proteomic analysis of mitochondria associated membranes in renal ischemic reperfusion injury.
Melatonin alleviates T-2 toxin-induced oxidative damage, inflammatory response, and apoptosis in piglet spleen and thymus.
Canagliflozin improves fatty acid oxidation and ferroptosis of renal tubular epithelial cells via FOXA1-CPT1A axis in diabetic kidney disease.
f25, a novel synthetic quinoline derivative, inhibits tongue cancer cell invasion and survival by the PPAR pathway in vitro and vivo.
Cannabinoid type 2 receptors play a crucial role in social defeat-induced depression.
Elucidation of the anti-β-cell dedifferentiation mechanism of a modified Da Chaihu Decoction by an integrative approach of network pharmacology and experimental verification.
The circRNA hsa-circ-0013561 regulates head and neck squamous cell carcinoma development via the miR-7-5p/PDK3 axis.
Promoting collateral formation in type 2 diabetes mellitus using ultra-small nanodots with autophagy activation and ROS scavenging.
Ssc-miR-429 expression proliles and functions on inducing Leydig cells apoptosis.
Acupuncture alleviates CUMS-induced depression-like behaviors of rats by regulating oxidative stress, neuroinflammation and ferroptosis.
RAB22A as a predictor of exosome secretion in the progression and relapse of multiple myeloma.
TBBPS caused necroptosis and inflammation in hepatocytes by blocking PINK1-PARKIN-mediated mitochondrial autophagy.
Gastrodin Suppresses the Progression of Atherosclerosis and Vascular Inflammation by Regulating TLR4/NF-κB Pathway.
Alpha-lipoic Acid Prevents Bone Loss in Type 2 Diabetes and Postmenopausal Osteoporosis Coexisting Conditions by Modulating the YAP/Glut4 Pathway.
Integrating network pharmacology and experimental models to identify notoginsenoside R1 ameliorates atherosclerosis by inhibiting macrophage NLRP3 inflammasome activation.
Selenite selectively kills lung fibroblasts to treat bleomycin-induced pulmonary fibrosis.
Disruption of PABPN1 phase separation by SNRPD2 drives colorectal cancer cell proliferation and migration through promoting alternative polyadenylation of CTNNBIP1.
The small nucleolar RNA SNORA51 enhances breast cancer stem cell-like properties via the RPL3/NPM1/c-MYC pathway.
Hsa_circ_0001402 alleviates vascular neointimal hyperplasia through a miR-183-5p-dependent regulation of vascular smooth muscle cell proliferation, migration, and autophagy.
The components of the AhR-molecular chaperone complex differ depending on whether the ligands are toxic or non-toxic.
Combined BRAF and PIM1 inhibitory therapy for papillary thyroid carcinoma based on BRAFV600E regulation of PIM1: Synergistic effect and metabolic mechanisms.
Sodium Butyrate Ameliorates Atopic Dermatitis-Induced Inflammation by Inhibiting HDAC3-Mediated STAT1 and NF-κB Pathway.
4-Octyl Itaconate Inhibits Proinflammatory Cytokine Production in Behcet's Uveitis and Experimental Autoimmune Uveitis.
Photodynamic therapy inhibits cancer progression and induces ferroptosis and apoptosis by targeting P53/GPX4/SLC7A11 signaling pathways in cholangiocarcinoma.
In vitro modeling of recurrent Dermatofibrosarcoma Protuberans: Assessment of 5-aminolevulinic acid photodynamic therapy efficacy.
Reversine inhibits proliferation and induces apoptosis of human osteosarcoma cells through targeting MEK1.
Antitumor Effect of Apcin on Endometrial Carcinoma via p21-Mediated Cell Cycle Arrest and Apoptosis.
Insights into the role of the N6-methyladenosine reader IGF2BP3 in the progression of oral squamous cell carcinoma and its connection to cell-cycle control.
Licochalcone A alleviates ferroptosis in doxorubicin-induced cardiotoxicity via the PI3K/AKT/MDM2/p53 pathway.
Down-regulation of O-GlcNAcylation alleviates insulin signaling pathway impairment following arsenic exposure via suppressing the AMPK/mTOR-autophagy pathway.
Pseudorabies virus manipulates mitochondrial tryptophanyl-tRNA synthetase 2 for viral replication.
Germacrone alleviates breast cancer-associated osteolysis by inhibiting osteoclastogenesis via inhibition of MAPK/NF-κB signaling pathways.
Myricanol attenuates sepsis-induced inflammatory responses by nuclear factor erythroid 2-related factor 2 signaling and nuclear factor kappa B/mitogen-activated protein kinase pathway via upregulating Sirtuin 1.
MDSC-targeting gold nanoparticles enhance PD-1 tumor immunotherapy by inhibiting NLRP3 inflammasomes.
An ATPase-Mimicking MXene nanozyme pharmacologically breaks the ironclad defense system for ferroptosis cancer therapy.
Clinical features and molecular landscape of cuproptosis signature-related molecular subtype in gastric cancer.
MST1 knockdown inhibits osteoarthritis progression through Parkin-mediated mitophagy and Nrf2/NF-κB signalling pathway.
Fibroblast growth factor 21 enhances learning and memory performance in mice by regulating hippocampal L-lactate homeostasis.
LAGE3 promotes angiogenesis on hepatocellular carcinoma by stabilizing VEGFA mRNA.
Total flavonoids of Broussonetia papyrifera alleviate non-alcohol fatty liver disease via regulating Nrf2/AMPK/mTOR signaling pathways.
12-O-deacetyl-phomoxanthone A inhibits ovarian tumor growth and metastasis by downregulating PDK4.
Protective role of hydrogen sulfide against diabetic cardiomyopathy by inhibiting pyroptosis and myocardial fibrosis.
Synergistic effects of photodynamic therapy and chemotherapy: Activating the intrinsic/extrinsic apoptotic pathway of anoikis for triple-negative breast cancer treatment.
Stanniocalcin 2 Regulates Autophagy and Ferroptosis in Mammary Epithelial Cells of Dairy Cows Through the Mechanistic Target of Rapamycin Complex 1 Pathway.
Lack of vitamin D signalling in mesenchymal progenitors causes fatty infiltration in muscle.
Enhancement of autophagy can alleviate oxidative stress, inflammation, and apoptosis induced by ammonia stress in yellow catfish Pelteobagrus fulvidraco.
Fe(3)O(4)-Incorporated Metal-Organic Framework for Chemo/Ferroptosis Synergistic Anti-Tumor via the Enhanced Chemodynamic Therapy.
Elimination of radiation-induced senescent cancer cells and stromal cells in vitro by near-infrared photoimmunotherapy.
Ginsenoside Rh4 alleviates gastrointestinal mucositis and enhances chemotherapy efficacy through modulating gut microbiota.
Americanin B inhibits pyroptosis in lipopolysaccharide-induced septic encephalopathy mice through targeting NLRP3 protein.
Strictosamide alleviates acute lung injury via regulating T helper 17 cells, regulatory T cells, and gut microbiota.
Glucose regulates the HMGB1 signaling pathway through SIRT1 in glioma.
Mortalin promotes the evolution of androgen-independent prostate cancer through Wnt/β-catenin signaling pathway.
Identification of subclusters and prognostic genes based on GLS-associated molecular signature in ulcerative colitis.
Prognostic implications of TOR1B expression across cancer types: a focus on basal-like breast cancer and cellular adaptations to hypoxia.
Bile acid metabolism is altered in learning and memory impairment induced by chronic lead exposure.
FBP1 orchestrates keratinocyte proliferation/differentiation and suppresses psoriasis through metabolic control of histone acetylation.
Integrating network pharmacology and experimental validation reveals therapeutic effects of D-mannose on NAFLD through mTOR suppression.
Proteomics coupled transcriptomics reveals Slc34a1 and Slc34a3 downregulation as potential features of nephrotoxin-induced acute kidney injury.
Defective interferon signaling in the circulating monocytes of type 2 diabetic mice.
Cordycepin Enhances the Therapeutic Efficacy of Doxorubicin in Treating Triple-Negative Breast Cancer.
Nicotinate-curcumin improves NASH by inhibiting the AKR1B10/ACCα-mediated triglyceride synthesis.
Activation of aryl hydrocarbon receptor (AhR) alleviates depressive-like behaviors in LPS-induced mice.
A drug repurposing study identifies novel FOXM1 inhibitors with in vitro activity against breast cancer cells.
Expression Regulation of Gluconeogenesis Related Genes in Ovine Skeletal Muscle Cells.
Expression of VISTA regulated via IFN-γ governs endogenous T-cell function and exhibits correlation with the efficacy of CD19 CAR-T cell treated B-malignant mice.
Cytoplasmic TP53INP2 acts as an apoptosis partner in TRAIL treatment: the synergistic effect of TRAIL with venetoclax in TP53INP2-positive acute myeloid leukemia.
Renal inflammation combined with renal function reserve reduction accelerate kidney aging via pentose phosphate pathway.
Inhibiting Pink1/Parkin-mediated mitophagy enhances the anticancer effects of quercetin in hepatocellular carcinomaf.
Low PDE4A expression promoted the progression of ovarian cancer by inducing Snail nuclear translocation.
Asprosin promotes vascular inflammation via TLR4-NFκB-mediated NLRP3 inflammasome activation in hypertension.
Pseudolaric Acid B Targets CD147 to Selectively Kill Acute Myeloid Leukemia Cells.
ZFHX3 acts as a tumor suppressor in prostate cancer by targeting FTO-mediated m(6)A demethylation.
Yunvjian decoction mitigates hyperglycemia in rats induced by a high-fat diet and streptozotocin via reducing oxidative stress in pancreatic beta cells.
Integration of Proteomic and Metabolomic Data Reveals the Lipid Metabolism Disorder in the Liver of Rats Exposed to Simulated Microgravity.
Inefficacy of anti-VEGF therapy reflected in VEGF-mediated photoreceptor degeneration.
Lycorine attenuated proliferation and induced apoptosis on imatinib-resistant K562 cell by inhibiting autophagy.
Sodium-glucose cotransporter 1 promotes the biofunctions of perivascular preadipocytes mediated by Akt/mTOR/p70S6K signaling pathway.
Docosahexaenoic Acid Coordinating with Sodium Selenite Promotes Paraptosis in Colorectal Cancer Cells by Disrupting the Redox Homeostasis and Activating the MAPK Pathway.
Examining the molecular mechanisms of topiramate in alleviating insulin resistance: A study on C2C12 myocytes and 3T3L-1 adipocytes.
A Novel lncRNA lncRNA-4045 Promotes the Progression of Hepatocellular Carcinoma by Affecting the Expression of AKR1B10.
Postbiotics Prepared Using Lactobacillus reuteri Ameliorates Ethanol-Induced Liver Injury by Regulating the FXR/SHP/SREBP-1c Axis.
Hypoxia-mediated attenuation of EGLN2 inhibition of the NF-κB signaling pathway leads to the formation of a loop between HIF-1α and MUC1-C promoting chemoresistance in bladder cancer.
HHLA2 promotes hepatoma cell proliferation, migration, and invasion via SPP1/PI3K/AKT signaling pathway.
Circadian disruption reduces MUC4 expression via the clock molecule BMAL1 during dry eye development.
Reduced Malignancy of Super Methotrexate-resistant Osteosarcoma Cells With Dihydrofolate Reductase Amplification Despite Paradoxical Gain of Oncogenic PI3K/AKT/mTOR and c-MYC expression.
Major Facilitator Superfamily Domain Containing 12 Is Overexpressed in Lung Cancer and Exhibits an Oncogenic Role in Lung Adenocarcinoma Cells.
p97 inhibits integrated stress response-induced neuronal apoptosis after subarachnoid hemorrhage in mice by enhancing proteasome function.
A crucial role of adenosine deaminase in regulating gluconeogenesis in mice.
Mitochondria-targeted ruthenium complexes can be generated in vitro and in living cells to target triple-negative breast cancer cells by autophagy inhibition.
Calcitriol attenuates lipopolysaccharide-induced neuroinflammation and depressive-like behaviors by suppressing the P2X7R/NLRP3/caspase-1 pathway.
Isoprenylcysteine carboxyl methyltransferase (ICMT) promotes invadopodia formation and metastasis in cancer cells.
Grifolin Induces Cell Death of Human Lung Cancer A549 Cell Line via Inhibiting KRAS-Mediated Multiple Signaling Pathways.
SH-Alb inhibits phenotype remodeling of pro-fibrotic macrophage to attenuate liver fibrosis through SIRT3-SOD2 axis.
GRP78 Downregulation in Keratinocytes Promotes Skin Inflammation through the Recruitment and Activation of CCR6(+) IL-17A-Producing γδ T Cells.
HELQ deficiency impairs the induction of primordial germ cell-like cells.
The dual role of 20(S)-protopanaxadiol in alleviating pulmonary fibrosis through the gut-lung axis.
Celastrol mediates CAV1 to attenuate pro-tumorigenic effects of senescent cells.
IRAK1 deficiency potentiates the efficacy of radiotherapy in repressing cervical cancer development.
CircUGGT2 facilitates progression and cisplatin resistance of bladder cancer through nonhomologous end-joining pathway.
CD44v5 domain regulates crosstalk between TNBC cells and tumor-associated macrophages by enhancing the IL-4R/STAT3 axis.
Hypoxia-inducible factor-1α attenuates renal podocyte injury in male rats in a simulated high-altitude environment by upregulating Krüppel-like factor 4 expression.
Development of an integrated and project-based laboratory course in upper-level biochemistry and molecular biology.
Expression of PD-L1 Is Increased by Methionine Restriction Using Recombinant Methioninase in Human Colorectal Cancer Cells.
The impact of Nrf2 knockout on the neuroprotective effects of dexmedetomidine in a mice model of cognitive impairment.
Emodin alleviates intestinal ischemia-reperfusion injury through antioxidant stress, anti-inflammatory responses and anti-apoptosis effects via Akt-mediated HO-1 upregulation.
HOXC4 promotes proliferation of pancreatic cancer cells by increasing LDHA-mediated glycolysis.
Targeting the PI3K/AKT/mTOR pathway offer a promising therapeutic strategy for cholangiocarcinoma patients with high doublecortin-like kinase 1 expression.
Acetyl-11-keto-β-boswellic acid restrains the progression of synovitis in osteoarthritis via the Nrf2/HO-1 pathway.
Biomimetic NO Scavenging Hyaluronic Acid Nanoparticles Enable Targeted Delivery of MTX and Integrated Management of Rheumatoid Arthritis.
FERMT1 suppression induces anti-tumor effects and reduces stemness in glioma cancer cells.
Peptide PDRPS6 attenuates myocardial ischemia injury by improving mitochondrial function.
Dulaglutide restores endothelial progenitor cell levels in diabetic mice and mitigates high glucose-induced endothelial injury through SIRT1-mediated mitochondrial fission.
Targeted delivery of CEBPA-saRNA for the treatment of pancreatic ductal adenocarcinoma by transferrin receptor aptamer decorated tetrahedral framework nucleic acid.
A black phosphorus nanosheet-based RNA delivery system for prostate cancer therapy by increasing the expression level of tumor suppressor gene PTEN via CeRNA mechanism.
Paeoniflorin Promotes Ovarian Development in Mice by Activating Mitophagy and Preventing Oxidative Stress.
Metabolic reprogramming and heterogeneity during the decidualization process of endometrial stromal cells.
Lactylation of histone by BRD4 regulates astrocyte polarization after experimental subarachnoid hemorrhage.
Andrographolide sulfonate downregulation of TLR3-TRIF and amelioration of airway inflammation caused by respiratory syncytial virus infection.
The Coptidis Rhizoma and Bovis Calculus herb pair attenuates NASH and inhibits the NLRP3 inflammasome activation.
AP-1 inhibitor induces ferroptosis via the PI3K/AKT pathway in multiple myeloma cells.
Pathological polarizations from microglia to astrocyte contributes to spatial memory deficit in methamphetamine abstinence mice.
USP9X regulates the proliferation, survival, migration and invasion of gastric cancer cells by stabilizing MTH1.
Deciphering the Effects of the PYCR Family on Cell Function, Prognostic Value, Immune Infiltration in ccRCC and Pan-Cancer.
Bacillus coagulans restores pathogen-induced intestinal dysfunction via acetate-FFAR2-NF-κB-MLCK-MLC axis in Apostichopus japonicus.
Lipid-associated macrophages reshape BAT cell identity in obesity.
Molecular characterization and clinical relevance of metabolic signature subtypes in gastric cancer.
[ZIF-8@Pt Nanozyme Used for Scavenging Reactive Oxygen Species in the Treatment of Rheumatoid Arthritis].
Activation of PPAR-α attenuates myocardial ischemia/reperfusion injury by inhibiting ferroptosis and mitochondrial injury via upregulating 14-3-3η.
Type III adenylyl cyclase is essential for follicular development in female mice and their reproductive lifespan.
Mitochondrial miR-12294-5p-Regulated Copper Exposure-Caused Mitochondrial-Dependent Ferroptosis by Targeted Inhibition of CISD1 in Chicken Hepatocytes.
Morphine timing-dependent modulation of TRPV1 phosphorylation correlates with differential morphine effects on myocardial ischemia/reperfusion injury.
Bmal1 regulates female reproduction in mice via the hypothalamic-pituitary-ovarian axis.
Diquat causes mouse testis injury through inducing heme oxygenase-1-mediated ferroptosis in spermatogonia.
Glutamate rescues heat stress-induced apoptosis of Sertoli cells by enhancing the activity of antioxidant enzymes and activating the Trx1-Akt pathway in vitro.
Discovery of 5-(Piperidin-4-yl)-1,2,4-oxadiazole Derivatives as a New Class of Human Caseinolytic Protease P Agonists for the Treatment of Hepatocellular Carcinoma.
Melanoma-Derived Extracellular Vesicles Induce CD36-Mediated Pre-Metastatic Niche.
CD24 promotes metastasis and chemoresistance by directly targeting Arf6-ERK pathway in esophageal squamous cell carcinoma.
NAD(+) supplementation improves mitochondrial functions and normalizes glaucomatous trabecular meshwork features.
Pramipexole improves depression-like behavior in diabetes mellitus with depression rats by inhibiting NLRP3 inflammasome-mediated neuroinflammation and preventing impaired neuroplasticity.
Melatonin improves synapse development by PI3K/Akt signaling in a mouse model of autism spectrum disorder.
Pleiotropic effects of nitric oxide sustained-release system for peripheral nerve repair.
Disorder of neuroplasticity aggravates cognitive impairment via neuroinflammation associated with intestinal flora dysbiosis in chronic heart failure.
Mitofusin2 Ameliorated Endoplasmic Reticulum Stress and Mitochondrial Reactive Oxygen Species Through Maintaining Mitochondria-Associated Endoplasmic Reticulum Membrane Integrity in Cisplatin-Induced Acute Kidney Injury.
Activation of immune evasion machinery is a part of the process of malignant transformation of human cells.
miRNA-211-5p inhibition enhances the protective effect of hucMSC-derived exosome in Aβ(1-40) -induced SH-SY5Y cells by increasing NEP expression.
Endoplasmic reticulum stress-mediated autophagy alleviates lipopolysaccharide-induced nucleus pulposus cell pyroptosis by inhibiting CHOP signaling in vitro.
Integrating network pharmacology and transcriptomic omics reveals that akebia saponin D attenuates neutrophil extracellular traps-induced neuroinflammation via NTSR1/PKAc/PAD4 pathway after intracerebral hemorrhage.
IL-21 promoting angiogenesis contributes to the development of psoriasis.
A responsive hydrogel modulates innate immune cascade fibrosis to promote ocular surface reconstruction after chemical injury.
PVT1 promotes proliferation and macrophage immunosuppressive polarization through STAT1 and CX3CL1 regulation in glioblastoma multiforme.
USP11 promotes glycolysis by regulating HIF-1α stability in hepatocellular carcinoma.
ER-α36 is involved in calycosin inhibition of IL-6 production in macrophages.
Berberine alleviates contrast-induced nephropathy by activating Akt/Foxo3a/Nrf2 signalling pathway.
Localization and expression of phospholipase A(2) and polyunsaturated fatty acid profile in the testis tissues of Hu sheep.
pH-driven preparation of pea protein isolate-curcumin nanoparticles effectively enhances antitumor activity.
Angiotensin-converting enzyme inhibitory peptide IVGFPAYGH protects against liver injury in mice fed a high‑sodium diet by inhibiting the RAS and remodeling gut microbial communities.
A hyaluronic acid / chitosan composite functionalized hydrogel based on enzyme-catalyzed and Schiff base reaction for promoting wound healing.
Suppression of the SLC7A11/glutathione axis causes ferroptosis and apoptosis and alters the mitogen-activated protein kinase pathway in nasopharyngeal carcinoma.
Valine promotes milk synthesis by regulating PKM2 nuclear accumulation and histone H3 acetylation through the TAS1R1-mTOR-DDX39B signaling pathway.
A novel lncRNA GM15416 regulates osteoblast apoptosis and differentiation through the c-Fos/Fas axis and mitigates osteoporosis.
Fibroblast growth factor-21 alleviates proteasome injury via activation of autophagy flux in Parkinson's disease.
Crocetin inhibits choroidal neovascularization in both in vitro and in vivo models.
Driver gene KRAS aggravates cancer-associated stroke outcomes.
Carrier-free nanodrug targeting glucose metabolism for enhanced rheumatoid arthritis treatment.
MiR-548t-5p regulates pancreatic ductal adenocarcinoma metastasis through an IL-33-dependent crosstalk between cancer cells and M2 macrophages.
KAN0438757, a novel PFKFB3 inhibitor, prevent the progression of severe acute pancreatitis via the Nrf2/HO-1 pathway in infiltrated macrophage.
Electroacupuncture ameliorates chronic unpredictable mild stress-induced depression-like behavior and cognitive impairment through suppressing oxidative stress and neuroinflammation in rats.
Pseudorabies virus inhibits progesterone-induced inactivation of TRPML1 to facilitate viral entry.
CENPL accelerates cell proliferation, cell cycle, apoptosis, and glycolysis via the MEK1/2-ERK1/2 pathway in hepatocellular carcinoma.
IFN-γ enhances the therapeutic efficacy of MSCs-derived exosome via miR-126-3p in diabetic wound healing by targeting SPRED1.
Costunolide ameliorates angiotensin II-induced atrial inflammation and fibrosis by regulating mitochondrial function and oxidative stress in mice: A possible therapeutic approach for atrial fibrillation.
Bushen Antai recipe alleviates embryo absorption by enhancing immune tolerance and angiogenesis at the maternal-fetal interface via mobilizing MDSCs in abortion-prone mice.
Liproxstatin-1 alleviates cartilage degradation by inhibiting chondrocyte ferroptosis in the temporomandibular joint.
Decreased FoxO1 expression contributes to facet joint osteoarthritis pathogenesis by impairing chondrocyte migration and extracellular matrix synthesis.
Chrysophanol induces apoptosis and ferroptosis of gastric cancer cells by targeted regulation of mTOR.
Discovery of small molecule c-Maf inhibitors using molecular docking-based virtual screening, molecular dynamics simulation, and biological evaluation.
Hsa_circ_0013561 promotes progression of nasopharyngeal carcinoma by activating JAK2/STAT3 signaling pathway.
Polyphyllin II (PPII) Enhances the Sensitivity of Multidrug-resistant A549/DDP Cells to Cisplatin by Modulating Mitochondrial Energy Metabolism.
Protective effects of sodium humate on the intestinal barrier damage of Salmonella Typhimurium-challenged broilers.
The Herbal Combination Shu Gan Jie Yu Regulates the SNCG/ER-a/AKT-ERK Pathway in DMBA-Induced Breast Cancer and Breast Cancer Cell Lines Based on RNA-Seq and IPA Analysis.
Systematic Characterization of DNA Methyltransferases Family in Tumor Progression and Antitumor Immunity.
CRYL1 is a Potential Prognostic Biomarker of Clear Cell Renal Cell Carcinoma Correlated with Immune Infiltration and Cuproptosis.
Vancomycin relieves tacrolimus-induced hyperglycemia by eliminating gut bacterial beta-glucuronidase enzyme activity.
Lysosomal dynamics regulate mammalian cortical neurogenesis.
BACH1 changes microglial metabolism and affects astrogenesis during mouse brain development.
Aureusidin ameliorates 6-OHDA-induced neurotoxicity via activating Nrf2/HO-1 signaling pathway and preventing mitochondria-dependent apoptosis pathway in SH-SY5Y cells and Caenorhabditis elegans.
Autophagy induces hair follicle stem cell activation and hair follicle regeneration by regulating glycolysis.
miR-99b-3p/Mmp13 axis regulates NLRP3 inflammasome-dependent microglial pyroptosis and alleviates neuropathic pain via the promotion of autophagy.
Unlocking the role of EIF5A: A potential diagnostic marker regulating the cell cycle and showing negative correlation with immune infiltration in lung adenocarcinoma.
Protective Effect of Artocarpus heterophyllus Lam. (Jackfruit) Polysaccharides on Liver Injury Induced by Cyclophosphamide in Mice.
MiR-199a-5p inhibits dermal papilla cells proliferation by regulating VEGFA expression in cashmere goat.
Texture maintenance and degradation mechanism of ice-stored grass carp (Ctenopharyngodon idella): A scope of intramuscular connective tissue.
Investigation of the principle of concoction by using the processing excipient Glycyrrhiza uralensis Fisch. juice to reduce the main toxicity of Dioscorea bulbifera L. and enhance its main efficacy as expectorant and cough suppressant.
Flavonoid extract from propolis alleviates periodontitis by boosting periodontium regeneration and inflammation resolution via regulating TLR4/MyD88/NF-κB and RANK/NF-κB pathway.
Xingbei antitussive granules ameliorate cough hypersensitivity in post-infectious cough guinea pigs by regulating tryptase/PAR2/TRPV1 pathway.
Rescuing SERCA2 pump deficiency improves bone mechano-responsiveness in type 2 diabetes by shaping osteocyte calcium dynamics.
HIF-1A as a prognostic biomarker related to invasion, migration and immunosuppression of cervical cancer.
The Tautomerase Activity of Tumor Exosomal MIF Promotes Pancreatic Cancer Progression by Modulating MDSC Differentiation.
The inflammatory injury of porcine small intestinal epithelial cells induced by deoxynivalenol is related to the decrease in glucose transport.
Real-time monitoring of glucose metabolism and effects of metformin on HepG2 cells using (13)C in-cell NMR spectroscopy.
Visualization of the membrane surface and cytoskeleton of oligodendrocyte progenitor cell growth cones using a combination of scanning ion conductance and four times expansion microscopy.
Construction and Identification of a Breast Bioreactor for Human-Derived Hypoglycemic Protein Amylin.
κ-Opioid receptor activation attenuates osteoarthritis synovitis by regulating macrophage polarization through the NF-κB pathway.
Sodium humate ameliorates LPS-induced liver injury in mice by inhibiting TLR4/NF-κB and activating NRF2/HO-1 signaling pathways.
LGK974 suppresses the formation of deep vein thrombosis in mice with sepsis.
Monotropein induces autophagy through activation of the NRF2/PINK axis, thereby alleviating sepsis-induced colonic injury.
CXCL16 exacerbates Pseudomonas aeruginosa keratitis by promoting neutrophil activation.
Regulation of tumor metastasis and CD8(+) T cells infiltration by circRNF216/miR-576-5p/ZC3H12C axis in colorectal cancer.
Veratramine inhibits porcine epidemic diarrhea virus entry through macropinocytosis by suppressing PI3K/Akt pathway.
Tetrandrine (TET) inhibits African swine fever virus entry into cells by blocking the PI3K/Akt pathway.
LncRNA FOXD1-AS1 regulates pancreatic cancer stem cell properties and 5-FU resistance by regulating the miR-570-3p/SPP1 axis as a ceRNA.
Perfluorocarbon Nanoparticles Incorporating Ginkgolide B: Artificial O(2) Carriers with Antioxidant Activity and Antithrombotic Effect.
Proteomic analysis identifies PFKP lactylation in SW480 colon cancer cells.
Identification of key ferroptosis genes and mechanisms associated with breast cancer using bioinformatics, machine learning, and experimental validation.
Macrophage-expressed SRA ameliorates alcohol-induced liver injury by suppressing S-glutathionylation of Notch1 via recruiting thioredoxin.
Hypoxia-induced P4HA1 overexpression promotes post-ischemic angiogenesis by enhancing endothelial glycolysis through downregulating FBP1.
SLC7A8 overexpression inhibits the growth and metastasis of lung adenocarcinoma and is correlated with a dismal prognosis.
The mitochondrial ATP-dependent potassium channel (mitoK(ATP)) controls skeletal muscle structure and function.
Neutrophil extracellular trap-related mechanisms in acne vulgaris inspire a novel treatment strategy with adipose-derived stem cells.
Activation of TAZ by XMU-MP-1 inhibits osteoclastogenesis and attenuates ovariectomy-induced cancellous bone loss.
Mechanism through which the hsa-circ_0000992- hsa- miR- 936-AKT3 regulatory network promotes the PM(2.5)-induced inflammatory response in human bronchial epithelial cells.
Fluorochloridone induces mitochondrial dysfunction and apoptosis in primary goat Sertoli cells.
Resveratrol-βcd inhibited premature ovarian insufficiency progression by regulating granulosa cell autophagy.
Analysis of the effects of importin α1 on the nuclear translocation of IL-1α in HeLa cells.
The tertiary lymphoid structure-related signature identified PTGDS in regulating PD-L1 and promoting the proliferation and migration of glioblastoma.
Dictamnine Ameliorates DNFB-Induced Atopic Dermatitis Like Skin Lesions in Mice by Inhibiting M1 Macrophage Polarization and Promoting Autophagy.
Metabolic reprogramming based on RNA sequencing of gemcitabine-resistant cells reveals the FASN gene as a therapeutic for bladder cancer.
Molecular and functional characterization of porcine poly C binding protein 1 (PCBP1).
FBXO31 is upregulated by METTL3 to promote pancreatic cancer progression via regulating SIRT2 ubiquitination and degradation.
SLMO2 is a potential prognostic and immunological biomarker in human pan-cancer.
Phosphoproteomic landscape of pseudorabies virus infection reveals multiple potential antiviral targets.
Jianghu decoction and its active component polydatin inhibit inflammation and fibrotic lesions in the lungs of ILD mice via the AMPK signaling pathway.
Neuroprotective effects of Jie-du-huo-xue decoction on microglia pyroptosis after cerebral ischemia and reperfusion--From the perspective of glial-vascular unit.
Therapeutic effect of Hosta plantaginea (Lam.) Aschers flowers on acute pharyngitis through inhibition of multi-inflammatory pathways in rats.
Bushen Antai recipe ameliorates immune microenvironment and maternal-fetal vascularization in STAT3-deficient abortion-prone mice.
Network pharmacology, molecular docking and experimental verification of the mechanism of huangqi-jixuecao herb pair in treatment of peritoneal fibrosis.
Qinzhizhudan formula dampens inflammation in microglia polarization of vascular dementia rats by blocking MyD88/NF-κB signaling pathway: Through integrating network pharmacology and experimental validation.
A novel upregulated hsa_circ_0032746 regulates the oncogenesis of esophageal squamous cell carcinoma by regulating miR-4270/MCM3 axis.
MitomiR-1736-3p regulates copper-induced mitochondrial pathway apoptosis by inhibiting AATF in chicken hepatocytes.
miR-130b regulates B cell proliferation via CYLD-mediated NF-κB signaling.
Mechanistic study of the Aldo-keto reductase family 1 member A1 in regulating mesenchymal stem cell fate decision toward adipogenesis and osteogenesis.
Fenofibrate inhibits MOXD1 and PDZK1IP1 expression and improves lipid deposition and inflammation in mice with alcoholic fatty liver.
Anticancer effect of covalent purine-containing EGFR TKI, ZZC4 and its mechanism of action through network pharmacology.
Patulin induces ROS-dependent cardiac cell toxicity by inducing DNA damage and activating endoplasmic reticulum stress apoptotic pathway.
2-Deoxy-D-glucose ameliorates inflammation and fibrosis in a silicosis mouse model by inhibiting hypoxia-inducible factor-1α in alveolar macrophages.
SARS-CoV-2 nucleocapsid protein promotes TMAO-induced NLRP3 inflammasome activation by SCAP-SREBP signaling pathway.
Heterogeneous ferroptosis susceptibility of macrophages caused by focal iron overload exacerbates rheumatoid arthritis.
Enhancing HIF-1α-P2X2 signaling in dorsal raphe serotonergic neurons promotes psychological resilience.
Lead aggravates Alzheimer's disease pathology via mitochondrial copper accumulation regulated by COX17.
Partial Replacement of NaCl with KCl in Cooked Meat Could Reduce the Liver Damage Through Renin-Angiotensin System in Mice.
SENP1 inhibits ferroptosis and promotes head and neck squamous cell carcinoma by regulating ACSL4 protein stability via SUMO1.
Prenylated flavonoid fractions from Glycyrrhiza glabra alleviate insulin resistance in HepG2 cells by regulating the ERK/IRS-1 and PI3K/Akt signaling pathways.
FPR1 Antagonist (BOC-MLF) Inhibits Amniotic Epithelial-mesenchymal Transition.
SENP3 Promotes Mantle Cell Lymphoma Development through Regulating Wnt10a Expression.
Liver ACSM3 deficiency mediates metabolic syndrome via a lauric acid-HNF4α-p38 MAPK axis.
miR-1182-mediated ALDH3A2 inhibition affects lipid metabolism and progression in ccRCC by activating the PI3K-AKT pathway.
USP14 promotes the proliferation of cervical cancer via upregulating β-catenin.
Exosomal circ_0037104 derived from Hu-MSCs inhibits cholangiocarcinoma progression by sponging miR-620 and targeting AFAP1.
Manganese@Albumin Nanocomplex and Its Assembled Nanowire Activate TLR4-Dependent Signaling Cascades of Macrophages.
Genetically engineered M2-like macrophage-derived exosomes for P. gingivalis-suppressed cementum regeneration: From mechanism to therapy.
Leveraging synthetic lethality to uncover potential therapeutic target in gastric cancer.
KLF6 activates Sp1-mediated prolidase transcription during TGF-β(1) signaling.
Identification and validation of a glycolysis-related taxonomy for improving outcomes in glioma.
Infection of PRRSV inhibits CSFV C-strain replication by inducing macrophages polarization to M1.
Anthocyanin Extracted from Purple Sweet Potato Alleviates Dextran Sulfate Sodium-Induced Colitis in Mice by Suppressing Pyroptosis and Altering Intestinal Flora Structure.
Aurora kinase B disruption suppresses pathological retinal angiogenesis by affecting cell cycle progression.
Discovery of common molecular signatures and drug repurposing for COVID-19/Asthma comorbidity: ACE2 and multi-partite networks.
Dimerized sesquiterpenoid [4 + 2] adducts with ferroptosis-promoting activity from Inula britannica Linn.
The PTB and PRR domains of numb regulate neurite outgrowth by influencing voltage-gated calcium channel expression and kinetics.
Palbociclib sensitizes ER-positive breast cancer cells to fulvestrant by promoting the ubiquitin-mediated degradation of ER-α via SNHG17/Hippo-YAP axis.
Cholesterol-induced HRD1 reduction accelerates vascular smooth muscle cell senescence via stimulation of endoplasmic reticulum stress-induced reactive oxygen species.
Haploinsufficiency of Lipin3 leads to hypertriglyceridemia and obesity by disrupting the expression and nucleocytoplasmic localization of Lipin1.
Photobiomodulation therapy alleviates repeated closed head injury-induced anxiety-like behaviors.
Downregulation of KCNMA1 in mice accelerates auditory hair cells senescence via ferroptosis.
Data mining-guided alleviation of hyperuricemia by Paeonia veitchii Lynch through inhibition of xanthine oxidase and regulation of renal urate transporters.
Protective effect of TNFAIP3 on testosterone production in Leydig cells under an aging inflammatory microenvironment.
CpxAR two-component system contributes to virulence properties of Cronobacter sakazakii.
Astrocyte-Derived Extracellular Vesicular miR-143-3p Dampens Autophagic Degradation of Endothelial Adhesion Molecules and Promotes Neutrophil Transendothelial Migration after Acute Brain Injury.
USF2 promotes autophagy and proliferation in chronic lymphocytic leukemia by inhibiting STUB1-induced NFAT5 ubiquitination.
Chlamydia trachomatis upregulates lncRNA CYTOR to mediate autophagy through miR-206/MAPK1 axis.
The Ameliorative Role of Lico A on Aflatoxin B(1)-Triggered Hepatotoxicity Partially by Activating Nrf2 Signal Pathway.
Suppression of HCN channels in the spinal dorsal horn restores KCC2 expression and attenuates diabetic neuropathic pain.
Methionine restriction of glioma does not induce MGMT and greatly improves temozolomide efficacy in an orthotopic nude-mouse model: A potential curable approach to a clinically-incurable disease.
Design, synthesis and antitumor activity of 4-arylamine substituted pyrimidine derivatives as noncovalent EGFR inhibitors overcoming C797S mutation.
Epigenetic drug screening for trophoblast syncytialization reveals a novel role for MLL1 in regulating fetoplacental growth.
Wnt/β-catenin signalling activates IMPDH2-mediated purine metabolism to facilitate oxaliplatin resistance by inhibiting caspase-dependent apoptosis in colorectal cancer.
Loss of Slc39a12 in hippocampal neurons is responsible for anxiety-like behavior caused by temporomandibular joint osteoarthritis.
Analysis of the role of PANoptosis in seizures via integrated bioinformatics analysis and experimental validation.
TsMS combined with EA promotes functional recovery and axonal regeneration via mediating the miR-539-5p/Sema3A/PlexinA1 signalling axis in sciatic nerve-injured rats.
Dendrobine Ameliorates Alzheimer's Disease-like Pathology and Cognitive Decline in 3 × Tg-AD Mice.
An Inulin-Type Fructan CP-A from Codonopsis pilosula Alleviated 5-Fluorouracil-Induced Intestinal Mucositis via the ERK/MLCK/MLC2 Pathway and Regulation of Gut Microbiota.
VX-509 attenuates the stemness characteristics of colorectal cancer stem-like cells by regulating the epithelial-mesenchymal transition through Nodal/Smad2/3 signaling.
SLC25A17 inhibits autophagy to promote triple-negative breast cancer tumorigenesis by ROS-mediated JAK2/STAT3 signaling pathway.
ACACA reduces lipid accumulation through dual regulation of lipid metabolism and mitochondrial function via AMPK- PPARα- CPT1A axis.
Discovery of a Novel Series of Homo sapiens Caseinolytic Protease P Agonists for Colorectal Adenocarcinoma Treatment via ATF3-Dependent Integrated Stress Response.
The Parkinson's disease related mutant VPS35 (D620N) amplifies the LRRK2 response to endolysosomal stress.
Long noncoding RNA TMPO-AS1 accelerates glycolysis by regulating the miR-1270/PKM2 axis in colorectal cancer.
Prognosis and biological function of SGOL1 in clear cell renal cell carcinoma: a multiomics analysis.
Endothelial Robo4 suppresses endothelial-to-mesenchymal transition induced by irradiation and improves hematopoietic reconstitution.
The microbial metabolite urolithin A reduces Clostridioides difficile toxin expression and toxin-induced epithelial damage.
Complement components regulates ferroptosis in CVB3 viral myocarditis by interatction with TFRC.
AURKA Enhances the Glycolysis and Development of Ovarian Endometriosis Through ERβ.
Galectin-3 is involved in inflammation and fibrosis in arteriogenic erectile dysfunction via the TLR4/MyD88/NF-κB pathway.
LncRNA RPARP-AS1 promotes the progression of osteosarcoma cells through regulating lipid metabolism.
KIF18A inactivates hepatic stellate cells and alleviates liver fibrosis through the TTC3/Akt/mTOR pathway.
In Vitro Insights into the Role of 7,8-Epoxy-11-Sinulariolide Acetate Isolated from Soft Coral Sinularia siaesensis in the Potential Attenuation of Inflammation and Osteoclastogenesis.
A Mixture of Formic Acid, Benzoic Acid, and Essential Oils Enhanced Growth Performance via Modulating Nutrient Uptake, Mitochondrion Metabolism, and Immunomodulation in Weaned Piglets.
Solobacterium moorei promotes the progression of adenomatous polyps by causing inflammation and disrupting the intestinal barrier.
The neuroprotective effect of LCZ696 on methamphetamine-induced cognitive impairment in mice.
NLRP3-GSDMD-dependent IL-1β Secretion from Microglia Mediates Learning and Memory Impairment in a Chronic Intermittent Hypoxia-induced Mouse Model.
Protein phosphatase 1 regulatory subunit 15 A promotes translation initiation and induces G2M phase arrest during cuproptosis in cancers.
Potential Therapeutic Effects of Bifidobacterium breve MCC1274 on Alzheimer's Disease Pathologies in App(NL-G-F) Mice.
Exploring the therapeutic mechanisms and prognostic targets of Biochanin A in glioblastoma via integrated computational analysis and in vitro experiments.
Potential effects of different cell death inhibitors in protecting against ischemia-reperfusion injury in steatotic liver.
E. Coli LPS-induced calcium signaling regulates the expression of hypoxia-inducible factor 1α in periodontal ligament fibroblasts in a non-hypoxia-dependent manner.
Severe inflammation in C57/BL6 mice leads to prolonged cognitive impairment by initiating the IL-1β/TRPM2 pathway.
Intermittent Hypobaric Hypoxia Ameliorates Autistic-Like Phenotypes in Mice.
High expression of TBRG4 in relation to unfavorable outcome and cell ferroptosis in hepatocellular carcinoma.
Pharmacological effects and mechanism of Maxing Shigan decoction in the treatment of Pseudomonas aeruginosa pneumonia.
Sasanquasaponin from Camellia oleifera Abel Exerts an Anti-Inflammatory Effect in RAW 264.7 Cells via Inhibition of the NF-κB/MAPK Signaling Pathways.
AAA237, an SKP2 inhibitor, suppresses glioblastoma by inducing BNIP3-dependent autophagy through the mTOR pathway.
Antitumoral Potential of the Histone Demethylase Inhibitor GSK-J4 in Retinoblastoma.
β-Lapachone induces ferroptosis of colorectal cancer cells via NCOA4-mediated ferritinophagy by activating JNK pathway.
Systematic pan-cancer analysis of RNF186 with potential implications in progression and prognosis in human cancer.
Testosterone reduces hippocampal synaptic damage in an androgen receptor-independent manner.
Identification of DNA methylation biomarkers for evaluating cardiovascular disease risk from epigenome profiles altered by low-dose ionizing radiation.
Therapeutic potential of Lacticaseibacillus rhamnosus grx10 and its derived postbiotic through gut microbiota and MAPK/MLCK/MLC pathway-mediated intestinal barrier repairment in ulcerative colitis.
ALDH2 attenuates radiation-induced lung injury by inhibiting ROS and epithelial-mesenchymal transition mediated by the TGF-β1/Smad pathway.
Compromised cell competition exhausts neural stem cells pool.
MiR-143-5p regulates the proangiogenic potential of human dental pulp stem cells by targeting HIF-1α/RORA under hypoxia: A laboratory investigation in pulp regeneration.
Astrocyte-neuron crosstalk through extracellular vesicle-shuttled miRNA-382-5p promotes traumatic brain injury.
Multi-omics profiling highlights karyopherin subunit alpha 2 as a promising biomarker for prognosis and immunotherapy respond in pediatric and adult adrenocortical carcinoma.
Shikonin from lithospermum erythrorhizon induces pyroptosis in trophoblast cells by activating the CTSB-NLRP3 inflammasome.
Curcumin pretreatment attenuates myocardial ischemia/reperfusion injury by inhibiting ferroptosis, autophagy and apoptosis via HES1.
Regulation of lipid metabolism in grass carp primary hepatocytes by exosomes derived from fatty hepatocytes though GRP78.
Tripartite-motif 3 represses ovarian cancer progression by downregulating lactate dehydrogenase A and inhibiting AKT signaling.
Melatonin antagonizes oxidative stress-induced apoptosis in retinal ganglion cells through activating the thioredoxin-1 pathway.
Targeting CA9 restricts pancreatic cancer progression through pH regulation and ROS production.
USP28 promotes tumor progression and glycolysis by stabilizing PKM2/Hif1-α in cholangiocarcinoma.
TXNIP deficiency attenuates renal fibrosis by modulating mTORC1/TFEB-mediated autophagy in diabetic kidney disease.
Decoction of Yougui Wan combined with Wuzi Yanzong Wan ameliorates thin endometrium in a mouse model.
Metformin enhances epithelial cell growth inhibition via the protein kinase-insulin-like growth factor binding protein-1 pathway.
Mesenchymal stem cells may alleviate angiotensin II-induced myocardial fibrosis and hypertrophy by upregulating SFRS3 expression.
Intraoperative blood auto-transfusion restrained the malignancy of Liver Cancer via regulating functions of tumor cells and Kuffer cells.
Efficient and robust reverse genetics system for bovine rotavirus generation and its application for antiviral screening.
Pachymic acid ameliorates bleomycin-induced pulmonary fibrosis through inhibiting endoplasmic reticulum stress in rats.
Design, synthesis, and evaluation of cyclic C7-bridged monocarbonyl curcumin analogs containing an o-methoxy phenyl group as potential agents against gastric cancer.
Mesenchymal stem cell-loaded hydrogel to inhibit inflammatory reaction in surgical brain injury via mitochondria transfer.
Novel benzothiazole/benzothiazole thiazolidine-2,4-dione derivatives as potential FOXM1 inhibitors: In silico, synthesis, and in vitro studies.
In situ customized apolipoprotein B48-enriched protein corona enhances oral gene delivery of chitosan-based nanoparticles.
A Novel Compound Ligusticum Cycloprolactam Alleviates Neuroinflammation After Ischemic Stroke via the FPR1/NLRP3 Signaling Axis.
The effects of Cordyceps polysaccharides on ischemic brain injury in rats via intervening with IL-23/IL-17 axis and the intestinal barrier.
miR-221-5p_R-4 regulates internalized trehalose-induced autophagy by targeting NRBF2 in porcine granulosa cells.
RVG-peptide-camouflaged iron-coordinated engineered polydopamine nanoenzyme with ROS scavenging and inhibiting inflammatory response for ischemic stroke therapy.
Indole-3-Carboxaldehyde Inhibits Inflammatory Response and Lipid Accumulation in Macrophages Through the miR-1271-5p/HDAC9 Pathway.
Benzaldehyde stimulates autophagy via the sonic hedgehog signaling pathway in mouse brain astrocytes after treatment with Angiostrongylus cantonensis excretory-secretory products.
Glycogenesis and glyconeogenesis from glutamine, lactate and glycerol support human macrophage functions.
Tanshinone IIA Exerts Cardioprotective Effects Through Improving Gut-Brain Axis Post-Myocardial Infarction.
Activation of ferritin light chain (FTL) by transcription factor salmonella pathogenicity island 1 modulates glycolysis to drive metastasis of ovarian cancer cells.
Activation of the γ-secretase/NICD-PXR/Notch pathway induces Taxol resistance in triple-negative breast cancer.
Skin as outermost immune organ of vertebrates that elicits robust early immune responses after immunization with glycoprotein of spring viraemia of carp virus.
Dual-activity nanozyme as an oxygen pump to alleviate tumor hypoxia and enhance photodynamic/ NIR-II photothermal therapy for sniping oral squamous cell carcinoma.
Molecular mechanism through which Tripterygium hypoglaucum (Lévl.) Hutch alleviates psoriasis.
Deciphering the therapeutic potential of Myeloid-Specific JAK2 inhibition in acute respiratory distress syndrome.
Integrin αVβ3 mediates porcine deltacoronavirus infection and inflammatory response through activation of the FAK-PI3K-AKT-nf-κB signalling pathway.
Green tea polyphenol alleviates silica particle-induced lung injury by suppressing IL-17/NF-κB p65 signaling-driven inflammation.
Icariin ameliorates Coxsackievirus B3-induced viral myocarditis by modulating the S100 calcium binding protein A6/β-catenin/c-Myc signaling pathway.
Huangqi-Danshen decoction improves heart failure by regulating pericardial adipose tissue derived extracellular vesicular miR-27a-3p to activate AMPKα2 mediated mitophagy.
4-Hydroxydictyolactone alleviates cerebral ischemia injury by regulating neuroinflammation and autophagy via AMPK signaling pathway.
Hesperidin alleviated dendritic spines through inhibiting ferritinophagy via HERC2-NCOA4 ubiquitination in CUMS mice.
New finding based on Comparative Toxicogenomics Database: Hepatic YY1 mediates drug-induced liver injury.
A multi-omic analysis reveals that Gamabufotalin exerts anti-hepatocellular carcinoma effects by regulating amino acid metabolism through targeting STAMBPL1.
Investigating the effects of COVID-19 on sperm in male smokers: A prospective integrated proteomic and metabolomic study.
Identification of cepharanthine as an effective inhibitor of African swine fever virus replication.
MEK inhibitor trametinib combined with PI3K/mTOR inhibitor BEZ-235 as an effective strategy against NSCLC through impairment of glucose metabolism.
Design and characterization of defined alpha-helix mini-proteins with intrinsic cell permeability.
Parkinson Disease -Targeted Nanocapsules for Synergistic Treatment: Combining Dopamine Replacement and Neuroinflammation Mitigation.
Proteogenomic Landscape of Breast Ductal Carcinoma Reveals Tumor Progression Characteristics and Therapeutic Targets.
Up-regulated Lnc BTU promotes the production of duck plague virus DNA polymerase and inhibits the activation of JAK-STAT pathway to facilitate duck plague virus replication.
Adropin regulates macrophage phenotype via PPARγ signalling: A preliminary study of adropin and Crohn's disease.
Pericancerous cross-presentation to cytotoxic T lymphocytes impairs immunotherapeutic efficacy in hepatocellular carcinoma.
Targeting the immune privilege of tumor-initiating cells to enhance cancer immunotherapy.
Magnesium-Based Composite Calcium Phosphate Cement Promotes Osteogenesis and Angiogenesis for Minipig Vertebral Defect Regeneration.
Exercise preconditioning mitigates Ischemia-Reperfusion injury in rats by enhancing mitochondrial respiration.
Gypenoside A-loaded mPEG-PLGA nanoparticles ameliorate high-glucose-induced retinal microvasculopathy by inhibiting ferroptosis.
A tiered toxicity testing strategy for assessing early life stage toxicity in estuarine fish (Mugilogobius chulae): A case study on tris (1-chloro-2-propyl) phosphate ester.
Investigating the potential risk of cadmium exposure on seizure severity and anxiety-like behaviors through the ferroptosis pathway in epileptic mice: An integrated multi-omics approach.
Discovery of non-antiproliferative selective estrogen receptor degraders (SERDs) based on scaffold optimization of elacestrant.
Allosteric site identification, virtual screening and discovery of a sulfonamide Hsp110-STAT3 interaction inhibitor for the treatment of hypoxic pulmonary arterial hypertension.
SENP3-FIS1 axis promotes mitophagy and cell survival under hypoxia.
RG108 attenuates acute kidney injury by inhibiting P38 MAPK/FOS and JNK/JUN pathways.
Evaluation of ALKBH2 and ALKBH3 gene regulation in patients with adult T-cell leukemia/lymphoma.
Uric acid mediates kidney tubular inflammation through the LDHA/ROS/NLRP3 pathway.
Epigenetic silencing ZSCAN23 promotes pancreatic cancer growth by activating Wnt signaling.
hnRNPLL regulates MYOF alternative splicing and correlates with early metastasis in pancreatic ductal adenocarcinoma.
SLC15A2 Serves as a Novel Prognostic Biomarker and Target for Prostate Cancer.
MicroRNA-668 alleviates renal fibrosis through PPARα/PGC-1α pathway.
Identification and validation of up-regulated TNFAIP6 in osteoarthritis with type 2 diabetes mellitus.
Identification of a novel immune checkpoint-related gene signature predicts prognosis and immunotherapy in breast cancer and experiment verification.
Acetyl-11-keto-β-boswellia acid attenuates Ti particle-induced osteoblastic oxidative stress and osteolysis through the Foxo3 signaling pathway.
Isoliquiritigenin alleviates neuropathic pain by reducing microglia inflammation through inhibition of the ERK signaling pathway and decreasing CEBPB transcription expression.
SUCNR 1 promotes atherosclerosis by inducing endoplasmic reticulum stress mediated ER-mito crosstalk.
Ibuprofen modulates macrophage polarization by downregulating poly (ADP-ribose) polymerase 1.
Micheliolide ameliorates severe acute pancreatitis in mice through potentiating Nrf2-mediated anti-inflammation and anti-oxidation effects.
-RAMP3 promotes hepatocellular carcinoma tumor cell-mediated CCL2 degradation by supporting membrane distribution of ACKR2.
Asiaticoside protects against lung injury induced by intestinal ischemia/reperfusion via the upregulation of FoxM1.
N1-methyladenosine RNA methylation patterns are associated with an increased risk to biochemical recurrence in prostate cancer and serve as a potential novel biomarker for patient stratification.
Sulforaphane potentiates the efficacy of chemoradiotherapy in glioblastoma by selectively targeting thioredoxin reductase 1.
Macrophage-derived cathepsin L promotes epithelial-mesenchymal transition and M2 polarization in gastric cancer.
SNRNP70 regulates the splicing of CD55 to promote osteosarcoma progression.
Nrf2/NRF1 signaling activation and crosstalk amplify mitochondrial biogenesis in the treatment of triptolide-induced cardiotoxicity using calycosin.
ANGPTL4 mediated mesothelial-mesenchymal transition in pulmonary fibrosis: a potential therapeutic target.
Inhibition of TFAM-Mediated Mitophagy by Oroxylin A Restored Sorafenib Sensitivity Under Hypoxia Conditions in HepG2 Cells.
Homoharringtonine promotes non-small-cell lung cancer cell death via modulating HIF-1α/ERβ/E2F1 feedforward loop.
Comparison of biocompatibility of epoxy resin and bioceramic-based root canal sealers.
TRAIP enhances progression of tongue squamous cell carcinoma through EMT and Wnt/β-catenin signaling by interacting with DDX39A.
NCAM1 modulates the proliferation and migration of pulmonary arterial smooth muscle cells in pulmonary hypertension.
17β-estradiol alleviated ferroptotic neuroinflammation by suppressing ATF4 in mouse model of Parkinson's disease.
Integrated network pharmacology and transcriptomics to explore the mechanism of compound Dihuang granule (CDG) protects dopaminergic neurons by regulating the Nrf2/HMOX1 pathway in the 6-OHDA/MPP(+)-induced model of Parkinson's disease.
IGF2BP2 promotes lung adenocarcinoma progression by regulating LOX1 and tumor-associated neutrophils.
Role of AhR-Hsp90-MDM2-mediated VDR ubiquitination in PM2.5-induced renal toxicity.
Chronic microcystin-leucine-arginine exposure induces osteoporosis by breaking the balance of osteoblasts and osteoclasts.
Matrine promotes colorectal cancer apoptosis by downregulating shank-associated RH domain interactor expression.
GS-4997 halts the progression of tubulointerstitial injury in lupus nephritis.
Overexpression of miR-133a-3p reduces microglia activation by binding to GCH1, alleviating neuroinflammation and neuropathic pain.
Endosome maturation is orchestrated by inside-out proton signaling through a Na+/H+ exchanger and pH-dependent Rab GTPase cycling.
Mycoplasma synoviae Induces Apoptosis in Chicken Oviduct Cells.
TRIM24-DTNBP1-ATP7A mediated astrocyte cuproptosis in cognition and memory dysfunction caused by Y(2)O(3) NPs.
Ion channel Piezo1 induces ferroptosis of trabecular meshwork cells: a novel observation in the pathogenesis in primary open angle glaucoma.
Integrated Analysis of Single-Cell and Bulk RNA Sequencing Reveals HSD3B7 as a Prognostic Biomarker and Potential Therapeutic Target in ccRCC.
TRPM7 contributes to pyroptosis and its involvement in status epilepticus.
O-GlcNAc participates in the meiosis of aging oocytes by mediating mitochondrial function.
Enhancing therapeutic efficacy in homologous recombination-proficient pancreatic cancer via the combination of PARP1-PROTAC and a BRD4 inhibitor.
Zishen Qingre Lishi Huayu Recipe May Ameliorate the Symptoms of PCOS Model Rats via Alleviating Systemic and Ovarian Inflammation.
Sweroside alleviates pressure overload-induced heart failure through targeting CaMKⅡδ to inhibit ROS-mediated NF-κB/NLRP3 in cardiomyocytes.
Cellular Retinoic Acid Binding Protein 2 (CRABP2), Up-regulated by HPV E6/E7, Leads to Aberrant Activation of the Integrin β1/FAK/ERK Signaling Pathway and Aggravates the Malignant Phenotypes of Cervical Cancer.
Anti-adipogenesis effect of indole-3-acrylic acid on human preadipocytes and HFD-induced zebrafish.
Methylene Blue Pretreatment Protects Against Repeated Neonatal Isoflurane Exposure-Induced Brain Injury and Memory Loss.
CCL2 Potentiates Inflammation Pain and Related Anxiety-Like Behavior Through NMDA Signaling in Anterior Cingulate Cortex.
Capsaicin attenuates Porphyromonas gingivalis-suppressed osteogenesis of periodontal ligament stem cells via regulating mitochondrial function and activating PI3K/AKT/mTOR pathway.
SNX14 inhibits autophagy via the PI3K/AKT/mTOR signaling cascade in breast cancer cells.
Toxicity mechanism of acrolein on energy metabolism disorder and apoptosis in human ovarian granulosa cells.
GOLPH3 inhibits erastin-induced ferroptosis in colorectal cancer cells.
The salt sensitivity of Drd4-null mice is associated with the upregulations of sodium transporters in kidneys.
Effect of Jiedu Huayu decoction on oral mucosal Axin and β-catenin expression in oral submucosal fibrosis model rats.
Ezetimibe ketone protects against renal ischemia-reperfusion injury and attenuates oxidative stress via activation of the Nrf2/HO-1 signaling pathway.
Exosomal miR-130b-3p suppresses metastasis of non-small cell lung cancer cells by targeting DEPDC1 via TGF-β signaling pathway.
A gelatin methacryloyl (GelMA) treated with gallic acid and coated with specially designed nanoparticles derived from ginseng enhances the healing of wounds in diabetic rats.
EYA4 reduces chemosensitivity of osteosarcoma to doxorubicin through DNA damage repair.
The Role of Histone H2B Acetylation Modification in Aluminum-Induced Cognitive Dysfunction.
Celastrol alleviates subconjunctival fibrosis induced by silicone implants mimicking glaucoma surgery.
NAMPT Overexpression Drives Cell Growth in Polycystic Liver Disease through Mitochondrial Metabolism Regulation.
Changes in PI3K/AKT and NRF2/HO-1 signaling expression and intestinal microbiota in bleomycin-induced pulmonary fibrosis.
PGC-1α/LDHA signaling facilitates glycolysis initiation to regulate mechanically induced bone remodeling under inflammatory microenvironment.
Novel meroterpene-like compounds inhibit ferroptosis through Fe(2+) chelation.
Gain-of-function variants in GSDME cause pyroptosis and apoptosis associated with post-lingual hearing loss.
Pharmacological control of angiogenesis by regulating phosphorylation of myosin light chain 2.
Degrasyn alleviates osteoarthritis by blocking macrophagic pyroptosis via suppressing NLRP3/GSDMD signaling pathway and protecting chondrocytes.
Extracellular vesicles derived from stored red blood cell suspensions enhance invasion and migration of lung cancer cells by miR1246 and miR150-3p.
CKB Promotes Mitochondrial ATP Production by Suppressing Permeability Transition Pore.
Inhibitory effects of Belamcanda extract on inflammatory response and antiviral mechanism in H9N2 Avian influenza virus: insights from in vitro and in vivo studies.
CircHIPK3/miR-124 affects angiogenesis in early-onset preeclampsia via CPT1A-mediated fatty acid oxidation.
A metabolic reprogramming-related gene signature correlates with prognosis and proliferation of BLCA.
PDIA3 orchestrates effector T cell program by serving as a chaperone to facilitate the non-canonical nuclear import of STAT1 and PKM2.
GelMA loaded with platelet lysate promotes skin regeneration and angiogenesis in pressure ulcers by activating STAT3.
Vasorin (VASN) overexpression promotes pulmonary metastasis and resistance to adjuvant chemotherapy in patients with locally advanced rectal cancer.
Identification of ferroptosis-related key genes associated with immune infiltration in sepsis by bioinformatics analysis and in vivo validation.
Inhibition of TFEB deacetylation in proximal tubular epithelial cells (TECs) promotes TFEB activation and alleviates TEC damage in diabetic kidney disease.
Bergenin protects against osteoarthritis by inhibiting STAT3, NF-κB and Jun pathways and suppressing osteoclastogenesis.
Inhibition of cGAS attenuates neonatal hypoxic-ischemic encephalopathy via regulating microglia polarization and pyroptosis.
Bacillus subtilis alleviates excessive apoptosis of intestinal epithelial cells in intrauterine growth restriction suckling piglets via the members of Bcl-2 and caspase families.
Combined bacterial translocation and cholestasis aggravates liver injury by activation pyroptosis in obstructive jaundice.
Indole-3-aldehyde Alleviates High-Fat Diet-Induced Gut Barrier Disruption by Increasing Intestinal Stem Cell Expansion.
Pterostilbene improves neurological dysfunction and neuroinflammation after ischaemic stroke via HDAC3/Nrf1-mediated microglial activation.
Regulatory effect of β-glucan secreted by Rhizobium pusense on triglyceride metabolism and their relationships with the modulation of intestinal microbiota in mice fed a high-fat diet.
NLRP4 renders pancreatic cancer resistant to olaparib through promotion of the DNA damage response and ROS-induced autophagy.
circNDUFA13 stimulates adipogenesis of bone marrow-derived mesenchymal stem cells via interaction with STAT3.
Tert promotes cardiac regenerative repair after MI through alleviating ROS-induced DNA damage response in cardiomyocyte.
MYH6 suppresses tumor progression by downregulating KIT expression in human prostate cancer.
Biallelic variants in DAP3 result in reduced assembly of the mitoribosomal small subunit with altered intrinsic and extrinsic apoptosis and a Perrault syndrome-spectrum phenotype.
ISIR and its human homolog gene AK131315 strengthen LPS-induced inflammation and acute lung injury by promoting TAK1-dependent NF-κB and MAPK signaling.
MiR-625-5p is a potential therapeutic target in sepsis by regulating CXCL16/CXCR6 axis and endothelial barrier.
Toll-like receptor 4 deficiency affects the balance of osteoclastogenesis and osteoblastogenesis in periodontitis.
Wedelolactone suppresses breast cancer growth and metastasis via regulating TGF-β1/Smad signaling pathway.
Taurine Alleviates Ferroptosis-Induced Metabolic Impairments in C2C12 Myoblasts by Stabilizing the Labile Iron Pool and Improving Redox Homeostasis.
miR-450a-2-3p targets ERK(1/2) to ameliorate ISO-induced cardiac fibrosis in mice.
Inhibiting PRMT1 protects against CoNV by regulating macrophages through the FGF2/PI3K/Akt pathway.
Potential mechanisms of aortic medial degeneration promoted by co-exposure to microplastics and lead.
The antihypertensive effect of Alizarin is achieved by activating VEGFR2/eNOS pathway, attenuating oxidative stress-induced mitochondrial damage and premature senescence.
Atorvastatin improved ulcerative colitis in association with gut microbiota-derived tryptophan metabolism.
Dietary rutin improves the antidiarrheal capacity of weaned piglets by improving intestinal barrier function, antioxidant capacity and cecal microbiota composition.
MicroRNA-486-3p affects cisplatin resistance in high-grade serous ovarian cancer by regulating TMIGD2: An experimental study.
Zhiqiao Gancao decoction regulated JAK2/STAT3/ macrophage M1 polarization to ameliorate intervertebral disc degeneration.
Butyrate promotes visceral hypersensitivity in IBS model via mast cell-derived DRG neuron lincRNA-01028-PKC-TRPV1 pathway.
Lys-63-specific deubiquitinase BRCC36 enhances the sensitivity of multiple myeloma cells to lenalidomide by inhibiting lysosomal degradation of cereblon.
Halting multiple myeloma with MALT1 inhibition: suppressing BCMA-induced NF-κB and inducing immunogenic cell death.
Mitochondrial dysfunction in kidney stones and relief of kidney stones after reducing mtROS.
Orai1 and Orai3 act through distinct signalling axes to promote stemness and tumorigenicity of breast cancer stem cells.
Effects of Ginsenoside Rb1 on the Crosstalk between Intestinal Stem Cells and Microbiota in a Simulated Weightlessness Mouse Model.
Comprehensive analysis identifies ubiquitin ligase FBXO42 as a tumor-promoting factor in neuroblastoma.
Exploration of the underlying mechanism of Astragaloside III in attenuating immunosuppression via network pharmacology and vitro/vivo pharmacological validation.
A novel PDGFR inhibitor WQ-C-401 prevents pulmonary vascular remodeling in rats with monocrotaline-induced pulmonary arterial hypertension.
Asprosin contributes to vascular remodeling in hypertensive rats via superoxide signaling.
Gut dysbiosis contributes to SCFAs reduction-associated adipose tissue macrophage polarization in gestational diabetes mellitus.
PARP1 inhibition prevents oxidative stress in age-related hearing loss via PAR-Ca(2+)-AIF axis in cochlear strial marginal cells.
Atorvastatin combined with imipenem alleviates lung injury in sepsis by inhibiting neutrophil extracellular trap formation via the ERK/NOX2 signaling pathway.
HSK3486 Inhibits Colorectal Cancer Growth by Promoting Oxidative Stress and ATPase Inhibitory Factor 1 Activation.
Disturbance of mitochondrial dynamics in myocardium of broilers with pulmonary hypertension syndrome.
Toll-like receptor 3 signaling drives enteric glial cells against dextran sulfate sodium-induced colitis in mice.
Botulinum Toxin Type A Alleviates Androgenetic Alopecia by Inhibiting Apoptosis of Dermal Papilla Cells via Targeting circ_0135062/miR-506-3p/Bax Axis.
A novel 2-iminobenzimidazole compound, XYA1353, displays in vitro and in vivo anti-myeloma activity via targeting NF-κB signaling.
Emodin suppresses alkali burn-induced corneal inflammation and neovascularization by the vascular endothelial growth factor receptor 2 signaling pathway.
Inflammatory Factor IL1α Induces Aberrant Astrocyte Proliferation in Spinal Cord Injury Through the Grin2c/Ca(2+)/CaMK2b Pathway.
Blood RNA-sequencing analysis in acrylamide-induced neurotoxicity and depressive symptoms in rats.
Manganese induces oxidative damage in the hippocampus by regulating the expression of oxidative stress-related genes via modulation of H3K18 acetylation.
Identification of fangchinoline as a broad-spectrum enterovirus inhibitor through reporter virus based high-content screening.
Pimpinellin ameliorates macrophage inflammation by promoting RNF146-mediated PARP1 ubiquitination.
Berberine ameliorates contrast-induced acute kidney injury by regulating HDAC4-FoxO3a axis-induced autophagy: In vivo and in vitro.
Integrated network pharmacology, molecular docking and pharmacodynamic study reveals protective effects and mechanisms of corilagin against cerebral ischemia-induced injury.
Sulfasalazine promotes ferroptosis through AKT-ERK1/2 and P53-SLC7A11 in rheumatoid arthritis.
BDE-47-induced damage prevented by melatonin in grass carp hepatocytes (L8824).
Astragaloside IV combined with ligustrazine ameliorates abnormal mitochondrial dynamics via Drp1 SUMO/deSUMOylation in cerebral ischemia-reperfusion injury.
GPX4-mediated bone ferroptosis under mechanical stress decreased bone formation via the YAP-TEAD signalling pathway.
Anionic polysaccharides benefit the bioavailability of pork myofibrillar protein gels: Evidence from a perspective of protein absorption and metabolism.
SARS-CoV-2 virus-like particle variants alpha and delta mimic the native viruses in their differential inflammasome activating potential.
Hydrogen sulfide improves endothelial barrier function by modulating the ubiquitination degradation of KLF4 through TRAF7 S-sulfhydration in diabetic aorta.
Tris-Functionalized Polyoxotungstovanadate-Mediated Antitumor Efficacy Involves Multiple Cell Death Pathways.
Mitigation effect of hesperidin on X-ray radiation-induced intestinal barrier dysfunction in Caco-2 cell monolayers.
Synergistic effect of cannabidiol with dasatinib on lung cancer by SRC/PI3K/AKT signal pathway.
Inhibition of PTPRE suppresses tumor progression and improves sorafenib response in hepatocellular carcinoma.
The bone-protective benefits of kaempferol combined with metformin by regulation of osteogenesis-angiogenesis coupling in OVX rats.
Koumine inhibits IL-1β-induced chondrocyte inflammation and ameliorates extracellular matrix degradation in osteoarthritic cartilage through activation of PINK1/Parkin-mediated mitochondrial autophagy.
Deficiency of immunoglobulin IgSF6 enhances antibacterial effects by promoting endoplasmic reticulum stress and the inflammatory response in intestinal macrophages.
Herb pair of Rhubarb-Astragalus mitigates renal interstitial fibrosis through downregulation of autophagy via p38-MAPK/TGF-β1 and p38-MAPK/smad2/3 pathways.
CyHV-2 infection triggers mitochondrial-mediated apoptosis in GiCF cells by upregulating the pro-apoptotic gene ccBAX.
New daphnane diterpenoidal 1,3,4-oxdiazole derivatives as potential anti-hepatoma agents: Synthesis, biological evaluation and molecular modeling studies.
Phenolics and terpenoids with good anti-inflammatory activity from the fruits of Amomum villosum and the anti-inflammatory mechanism of active diterpene.
Co-catalpol alleviates fluoxetine-induced main toxicity: Involvement of ATF3/FSP1 signaling-mediated inhibition of ferroptosis.
Neonatal resveratrol administration promotes skeletal muscle growth and insulin sensitivity in intrauterine growth-retarded suckling piglets associated with activation of FGF21-AMPKα pathway.
Effect of immunization against OPN5 on the reproductive performance in Shan Partridge ducks under different photoperiods.
Enterohemorrhagic Escherichia coli effector EspF triggers oxidative DNA lesions in intestinal epithelial cells.
UBA2 as a Prognostic Biomarker and Potential Therapeutic Target in Glioma.
Excessive fat expenditure in MCT-induced heart failure rats is associated with BMAL1/REV-ERBα circadian rhythmic loop disruption.
Jiawei Buzhong Yiqi decoction ameliorates polycystic ovary syndrome via oocyte-granulosa cell communication.
Tetrahydroberberine alleviates high-fat diet-induced hyperlipidemia in mice via augmenting lipoprotein assembly-induced clearance of low-density lipoprotein and intermediate-density lipoprotein.
Ginsenoside Rg1 promotes fetal hemoglobin production in vitro: A potential therapeutic avenue for β-thalassemia.
Senescent-like macrophages mediate angiogenesis for endplate sclerosis via IL-10 secretion in male mice.
Targeting hepatic ceruloplasmin mitigates nonalcoholic steatohepatitis by modulating bile acid metabolism.
POLQ inhibition attenuates the stemness and ferroptosis resistance in gastric cancer cells via downregulation of dihydroorotate dehydrogenase.
Blockade of PI3K/AKT signaling pathway by Astragaloside IV attenuates ulcerative colitis via improving the intestinal epithelial barrier.
Neuroprotective effects of takinib on an experimental traumatic brain injury rat model via inhibition of transforming growth factor beta-activated kinase 1.
Naringenin Inhibits Acid Sphingomyelinase-Mediated Membrane Raft Clustering to Reduce NADPH Oxidase Activation and Vascular Inflammation.
Electroacupuncture promotes macrophage/microglial M2 polarization and suppresses inflammatory pain through AMPK.
The Lipophilic Extract from Ginkgo biloba L. Leaves Promotes Glucose Uptake and Alleviates Palmitate-Induced Insulin Resistance in C2C12 Myotubes.
Induction of IFIT1/IFIT3 and inhibition of Bcl-2 orchestrate the treatment of myeloma and leukemia via pyroptosis.
Histone Lactylation Is Involved in Mouse Oocyte Maturation and Embryo Development.
Ginsenoside Rh2 shifts tumor metabolism from aerobic glycolysis to oxidative phosphorylation through regulating the HIF1-α/PDK4 axis in non-small cell lung cancer.
Rational Design of a Novel Class of Human ClpP Agonists through a Ring-Opening Strategy with Enhanced Antileukemia Activity.
Selenium binding protein 1 protects renal tubular epithelial cells from ferroptosis by upregulating glutathione peroxidase 4.
Neuroprotective effect of acetoxypachydiol against oxidative stress through activation of the Keap1-Nrf2/HO-1 pathway.
Exploration the mechanism of Shenling Baizhu San in the treatment of chronic obstructive pulmonary disease based on UPLC-Q-TOF-MS/MS, network pharmacology and in vitro experimental verification.
Oxymatrine Modulation of TLR3 Signaling: A Dual-Action Mechanism for H9N2 Avian Influenza Virus Defense and Immune Regulation.
Design, synthesis, and evaluation of novel ferrostatin derivatives for the prevention of HG-induced VEC ferroptosis.
The anti-apoptotic role of Ginkgolide B via mitochondrial permeability transition pore inhibition in retinal ischemia-reperfusion.
Baicalein alleviates intrahepatic cholestasis by regulating bile acid metabolism via an FXR-dependent manner.
Polar lipids modify Alzheimer's Disease pathology by reducing astrocyte pro-inflammatory signaling through platelet-activating factor receptor (PTAFR) modulation.
Up-regulation of HSP90α in HDM-induced asthma causes pyroptosis of airway epithelial cells by activating the cGAS-STING-ER stress pathway.
Protective effects of pulsed electromagnetic field therapy attenuates autophagy and apoptosis in osteoporotic osteoarthritis model rats by activating PPARγ.
Unveiling the therapeutic potential of Dl-3-n-butylphthalide in NTG-induced migraine mouse: activating the Nrf2 pathway to alleviate oxidative stress and neuroinflammation.
Necl-1/CADM3 regulates cone synapse formation in the mouse retina.
Identification and verification of the role of key metabolites and metabolic pathways on ASFV replication.
An LRPPRC-HAPSTR1-PSMD14 interaction regulates tumor progression in ovarian cancer.
Noninvasive Monitoring of Early Cardiac Fibrosis in Diabetic Mice by [(68)Ga]Ga-DOTA-FAPI-04 PET/CT Imaging.
Intratumor microbiome-derived butyrate promotes lung cancer metastasis.
Suppression of hypoxia-induced CAV1 autophagic degradation enhances nanoalbumin-paclitaxel transcytosis and improves therapeutic activity in pancreatic cancer.
Human Umbilical Cord Mesenchymal Stromal Cell-Derived Exosomes Alleviate Hypoxia-Induced Pulmonary Arterial Hypertension in Mice Via Macrophages.
Liquiritin reduces chondrocyte apoptosis through P53/PUMA signaling pathway to alleviate osteoarthritis.
13-oxyingenol dodecanoate derivatives induce mitophagy and ferroptosis through targeting TMBIM6 as potential anti-NSCLC agents.
Dapagliflozin ameliorates myocardial infarction injury through AMPKα-dependent regulation of oxidative stress and apoptosis.
Acupoints catgut embedding recovers leptin resistance via improving autophagy progress mediated by AMPK-mTOR signaling in obese mice.
METTL3 mediates SOX5 m6A methylation in bronchial epithelial cells to attenuate Th2 cell differentiation in T2 asthma.
Phosphoglycerate mutase 5 exacerbates liver ischemia-reperfusion injury by activating mitochondrial fission.
Rat Hepatocytes Protect against Lead-Cadmium-Triggered Apoptosis Based on Autophagy Activation.
Zearalenone Decreases Food Intake by Disrupting the Gut-Liver-Hypothalamus Axis Signaling via Bile Acids.
Icaritin with autophagy/mitophagy inhibitors synergistically enhances anticancer efficacy and apoptotic effects through PINK1/Parkin-mediated mitophagy in hepatocellular carcinoma.
CGRP Released by Corneal Sensory Nerve Maintains Tear Secretion of the Lacrimal Gland.
PARP inhibitor plus radiotherapy reshape the immune suppressive microenvironment and potentiate the efficacy of immune checkpoint inhibitors in tumors with IDH1 mutation.
High level 27-HC impairs trophoblast cell invasion and migration via LXR in pre-eclampsia.
Human gestational diabetes mellitus-derived exosomes impair glucose homeostasis in pregnant mice and stimulate functional maturation of offspring-islets.
A chemo/chemodynamic nanoparticle based on hyaluronic acid induces ferroptosis and apoptosis for triple-negative breast cancer therapy.
Adhesive hydrogel releases protocatechualdehyde-Fe(3+) complex to promote three healing stages for accelerated therapy of oral ulcers.
Senktide blocks aberrant RTN3 interactome to retard memory decline and tau pathology in social isolated Alzheimer's disease mice.
LncRNA GAS5 restrains ISO-induced cardiac fibrosis by modulating mir-217 regulation of SIRT1.
Liquiritigenin Attenuated Collagen-Induced Arthritis and Cardiac Complication via Inflammation and Fibrosis Inhibition in Mice.
Lin28B overexpression decreases let-7b and let-7g levels and increases proliferation and estrogen secretion in Dolang sheep ovarian granulosa cells.
Nanoengineered Gallium Ion Incorporated Formulation for Safe and Efficient Reversal of PARP Inhibition and Platinum Resistance in Ovarian Cancer.
Mechanisms of resveratrol against diabetic wound by network pharmacology and experimental validation.
Maslinic Acid Ameliorates Myocardial Ischemia Reperfusion Injury-Induced Oxidative Stress via Activating Nrf2 and Inhibiting NF-[Formula: see text]B Pathways.
MiR-328-3p promotes TGF-β1-induced proliferation, migration, and inflammation of airway smooth muscle cells by regulating the PTEN/Akt pathway.
Inhibition of cGAS aggravated the host inflammatory response to Aspergillus fumigatus.
The mechanism of monobutyl phthalate -induced ferroptosis via TNF/IL6/STAT3 signal pathway in TM-3 cells.
A Novel Myricetin Derivative with Anti-cancer Properties Induces Cell Cycle Arrest and Apoptosis in A549 Cells.
Absent in melanoma 2 attenuates proliferation and migration and promotes apoptosis of human colorectal cancer cells by activating P38MAPK signaling pathway.
MiR-124 Reduced Neuroinflammation after Traumatic Brain Injury by Inhibiting TRAF6.
Inhibition of Galectin-3 in a Rat Model of Epilepsy and Kainate-Activated BV2 Cells Limits Microglial Activation Through the NLRP3/Pyroptosis Pathway.
Considering the protective effect of exendin-4 against oxidative stress in spiral ganglion neurons.
Persistent Müllerian duct syndrome in an assisted reproductive patient: a novel variant impairs the biosynthesis and secretion of anti-Müllerian hormone (AMH).
Exosomes derived from BMSCs ameliorate cyclophosphamide-induced testosterone deficiency by enhancing the autophagy of Leydig cells via the AMPK-mTOR signaling pathway.
Montelukast Inhibits Lung Cancer Cell Migration by Suppressing Cysteinyl Leukotriene Receptor 1 Expression In vitro.
Static Magnetic Field Promotes Proliferation, Migration, Differentiation, and AKT Activation of Periodontal Ligament Stem Cells.
OL-FS13 Alleviates Cerebral Ischemia-reperfusion Injury by Inhibiting miR-21-3p Expression.
Up-regulated SPP1 increases the risk from IPF to lung cancer via activating the pro-tumor macrophages.
RRP Regulates Autophagy through the AMPK Pathway to Alleviate the Effect of Cell Senescence on Atherosclerosis.
miR-145 Alleviates Smooth Muscle Cell Phenotype Transition via ADAM17-Mediated ACE2 Shedding.
Diet Control and Swimming Exercise Ameliorate HFD-Induced Cognitive Impairment Related to the SIRT1-NF-κB/PGC-1α Pathways in ApoE-/- Mice.
A Water-Soluble Hydrogen Sulfide Donor Suppresses the Growth of Hepatocellular Carcinoma via Inhibiting the AKT/GSK-3β/β-Catenin and TGF-β/Smad2/3 Signaling Pathways.
Plumbagin Enhances the Anticancer Effects of PF Chemotherapy via Downregulation of the PI3K/AKT/mTOR/p70S6K Pathway in Human Tongue Squamous Cell Carcinoma.
Jia-Wei-Kai-Xin-San Treatment Alleviated Mild Cognitive Impairment through Anti-Inflammatory and Antiapoptotic Mechanisms in SAMP8 Mice.
Empagliflozin-Pretreated Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Attenuated Heart Injury.
Cartilage Damage Pathological Characteristics of Diabetic Neuropathic Osteoarthropathy.
IFN-α-2b Reduces Postoperative Arthrofibrosis in Rats by Inhibiting Fibroblast Proliferation and Migration through STAT1/p21 Signaling Pathway.
Adjuvant Efficacy of the ECMS-Oil on Immune Responses against Bordetella bronchiseptica in Mice through the TLR2/MyD88/NF-κB Pathway.
TRPM2 facilitates tumor progression of clear cell renal cell carcinoma by relieving Endoplasmic Reticulum Stress.
Quantitative Measurement of Transthyretin Mistargeting by Proximity Labeling and Parallel Reaction Monitoring.
Sphingosine-1-Phosphate Receptor 4 Attenuates Neutrophilic Airway Inflammation in Experimental Asthma via Repressing Proinflammatory Macrophage Activation.
Antioxioxidant and antiapoptotic effects of Thymosin β4 in Aβ-induced SH-SY5Y cells via the 5-HTR1A/ERK axis.
Thalidomide Alleviates Apoptosis, Oxidative Damage and Inflammation Induced by Pemphigus Vulgaris IgG in HaCat Cells and Neonatal Mice Through MyD88.
Zhiqiao Gancao Decoction Ameliorates Hyperalgesia in Lumbar Disc Herniation via the CCL2/CCR2 Signaling Pathway.
ZEB1 Transcriptionally Activates PHGDH to Facilitate Carcinogenesis and Progression of HCC.
GW4869 Can Inhibit Epithelial-Mesenchymal Transition and Extracellular HSP90α in Gefitinib-Sensitive NSCLC Cells.
18β-Glycyrrhetinic Acid Alleviates P. multocida-Induced Vascular Endothelial Inflammation by PARP1-Mediated NF-κB and HMGB1 Signalling Suppression in PIEC Cells.
Profilin1 Promotes Renal Tubular Epithelial Cell Apoptosis in Diabetic Nephropathy Through the Hedgehog Signaling Pathway.
Exogenous Hydrogen Sulfide Induces A375 Melanoma Cell Apoptosis Through Overactivation of the Unfolded Protein Response.
Dysfunction of inhibitory interneurons contributes to synaptic plasticity via GABABR-pNR2B signaling in a chronic migraine rat model.
Resveratrol suppresses neuroinflammation to alleviate mechanical allodynia by inhibiting Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway in a rat model of spinal cord injury.
Irisin Ameliorates PM2.5-Induced Acute Lung Injury by Regulation of Autophagy Through AMPK/mTOR Pathway.
Increasing autophagy ameliorates all-trans-retinal-activated NLRP3 inflammasomes in human THP-1 macrophages.
Long non-coding RNA LINC00707, a prognostic marker, regulates cell proliferation, apoptosis, and EMT in esophageal squamous cell carcinoma.
Inhibition of Piezo1 Ameliorates Intestinal Inflammation and Limits the Activation of Group 3 Innate Lymphoid Cells in Experimental Colitis.
Large-Scale Identification of Lysine Crotonylation Reveals Its Potential Role in Oral Squamous Cell Carcinoma.
A Y374X TDP43 truncation leads to an altered metabolic profile in amyotrophic lateral sclerosis fibroblasts driven by pyruvate and TCA cycle intermediate alterations.
APEX1 predicts poor prognosis of gallbladder cancer and affects biological properties of CD133(+) GBC-SD cells via upregulating Jagged1.
MUC15 is an independent prognostic factor that promotes metastases of MYCN non-amplified neuroblastoma.
Cyclin dependent kinase 14 as a paclitaxel-resistant marker regulated by the TGF-β signaling pathway in human ovarian cancer.
Leveraging a gene signature associated with disulfidptosis identified by machine learning to forecast clinical outcomes, immunological heterogeneities, and potential therapeutic targets within lower-grade glioma.
Design, synthesis, and evaluation of 4-(3-(3,5-dimethylisoxazol-4-yl)benzyl)phthalazin-1(2H)-one derivatives: potent BRD4 inhibitors with anti-breast cancer activity.
Shikimic acid (SA) inhibits neuro-inflammation and exerts neuroprotective effects in an LPS-induced in vitro and in vivo model.
High expression of P-selectin induces neutrophil extracellular traps via the PSGL-1/Syk/Ca(2+)/PAD4 pathway to exacerbate acute pancreatitis.
Design and synthesis of cabotegravir derivatives bearing 1,2,3-triazole and evaluation of anti-liver cancer activity.
Midgut microbiota affects the intestinal barrier by producing short-chain fatty acids in Apostichopus japonicus.
Unveiling the role of hypoxic macrophage-derived exosomes in driving colorectal cancer progression.
METTL3 promotes drug resistance to oxaliplatin in gastric cancer cells through DNA repair pathway.
Anti-inflammatory and analgesic effects of Streblus indicus.
Porcine epidemic diarrhea virus causes diarrhea by activating EGFR to regulates NHE3 activity and mobility on plasma membrane.
18-α-glycyrrhetinic acid alleviates oxidative damage in periodontal tissue by modulating the interaction of Cx43 and JNK/NF-κB pathways.
Glucosyl hesperidin exhibits more potent anxiolytic activity than hesperidin accompanied by the attenuation of noradrenaline induction in a zebrafish model.
Effect of arsenic stress on the intestinal structural integrity and intestinal flora abundance of Cyprinus carpio.
A new acid isolated from V. negundo L. inhibits NLRP3 inflammasome activation and protects against inflammatory diseases.
Transcriptomic and functional analyses reveal the molecular mechanisms underlying Fe-mediated tobacco resistance to potato virus Y infection.
Integrated analysis of cell-specific gene expression in peripheral blood using ISG15 as a marker of rejection in kidney transplantation.
NADPH-dependent ROS accumulation contributes to the impaired osteogenic differentiation of periodontal ligament stem cells under high glucose conditions.
Wogonin induces ferroptosis in pancreatic cancer cells by inhibiting the Nrf2/GPX4 axis.
Effect of botanical drugs in improving symptoms of hypertensive nephropathy: Analysis of real-world data, retrospective cohort, network, and experimental assessment.
GPR35 antagonist CID-2745687 attenuates anchorage-independent cell growth by inhibiting YAP/TAZ activity in colorectal cancer cells.
Adjuvant therapy with Huatan Sanjie Granules improves the prognosis of patients with primary liver cancer: a cohort study and the investigation of its mechanism of action based on network pharmacology.
Vitamin D-VDR (vitamin D receptor) alleviates glucose metabolism reprogramming in lipopolysaccharide-induced acute kidney injury.
CENPH overexpression promotes the progression, cisplatin resistance, and poor prognosis of lung adenocarcinoma via the AKT and ERK/P38 pathways.
Metabolic genes, a potential predictor of prognosis and immunogenicity of clear cell renal cell carcinoma.
MOGS promotes stemness acquisition and invasion via enhancing NOTCH1-glycosylation dependent NOTCH pathway in colorectal cancer.
Japanese encephalitis virus perturbs PML-nuclear bodies by engaging in interactions with distinct porcine PML isoforms.
Crosstalk between septic shock and venous thromboembolism: a bioinformatics and immunoassay analysis.
Afatinib combined with anti-PD1 enhances immunotherapy of hepatocellular carcinoma via ERBB2/STAT3/PD-L1 signaling.
Identification of a chemoresistance-related prognostic gene signature by comprehensive analysis and experimental validation in pancreatic cancer.
ITGB1-mediated molecular landscape and cuproptosis phenotype induced the worse prognosis in diffuse gastric cancer.
Methylation-mediated silencing of EDN3 promotes cervical cancer proliferation, migration and invasion.
L-Kynurenine participates in cancer immune evasion by downregulating hypoxic signaling in T lymphocytes.
MK8617 inhibits M1 macrophage polarization and inflammation via the HIF-1α/GYS1/UDPG/P2Y(14) pathway.
Downregulation of lncRNA SLC7A11-AS1 decreased the NRF2/SLC7A11 expression and inhibited the progression of colorectal cancer cells.
FBXO5 acts as a novel prognostic biomarker for patients with cervical cancer.
KLF2 is a clinical diagnostic and treatment biomarker of breast cancer.
Effect of stem cell conditional medium-loading adhesive hydrogel on TGF-β1-induced endometrial stromal cell fibrosis.
Comprehensive Genomic Profiling Identifies FAT1 as a Negative Regulator of EMT, CTCs, and Metastasis of Hepatocellular Carcinoma.
Identification of novel candidate targets for suppressing ovarian cancer progression through IL-33/ST2 axis components using the system biology approach.
The effect of allyl isothiocyanate on chondrocyte phenotype is matrix stiffness-dependent: Possible involvement of TRPA1 activation.
Single-cell data analysis of malignant epithelial cell heterogeneity in lung adenocarcinoma for patient classification and prognosis prediction.
High-expressed PTPN1 promotes tumor proliferation signature in human hepatocellular carcinoma.
Role of iron in host-microbiota interaction and its effects on intestinal mucosal growth and immune plasticity in a piglet model.
Targeting ARF1-IQGAP1 interaction to suppress colorectal cancer metastasis and vemurafenib resistance.
TGF-β3 Protects Neurons Against Intermittent Hypoxia-Induced Oxidative Stress and Apoptosis Through Activation of the Nrf-2/KEAP1/HO-1 Pathway via Binding to TGF-βRI.
Antitumor Effects of β-Elemene Through Inducing Autophagy-Mediated Apoptosis in Ewing Sarcoma Family Tumor Cells.
HIV-1 Infection Promotes Cholesterol Aggregation by Inducing miR-33b-5p to Suppress ABCA1 Expression.
ANRIL regulating the secretion of Muc5ac induced by atmospheric PM(2.5) via NF-κB pathway in Beas-2B cells.
STAMBPL1 promotes the progression of lung adenocarcinoma by inhibiting DHRS2 expression.
Apelin-Overexpressing Neural Stem Cells in Conjunction with a Silk Fibroin Nanofiber Scaffold for the Treatment of Traumatic Brain Injury.
rhFGF-21 accelerates corneal epithelial wound healing through the attenuation of oxidative stress and inflammatory mediators in diabetic mice.
Pancreatic stellate cell-derived exosomal tRF-19-PNR8YPJZ promotes proliferation and mobility of pancreatic cancer through AXIN2.
ZBTB7C m6A modification incurred by METTL3 aberration promotes osteosarcoma progression.
Potential antidepressant-like effects of N-3 polyunsaturated fatty acids through inhibition of endoplasmic reticulum stress.
Neuroprotective effect of salidroside on hippocampal neurons in diabetic mice via PI3K/Akt/GSK-3β signaling pathway.
SIRT3 regulates mitophagy in liver fibrosis through deacetylation of PINK1/NIPSNAP1.
ENPP2 inhibitor improves proliferation in AOM/DSS-induced colorectal cancer mice via remodeling the gut barrier function and gut microbiota composition.
Arsenic induced autophagy-dependent apoptosis in hippocampal neurons via AMPK/mTOR signaling pathway.
Xianlinglianxiafang Inhibited the growth and metastasis of triple-negative breast cancer via activating PPARγ/AMPK signaling pathway.
Caffeoylquinic acids isolated from Lonicera japonica Thunb. as TAK1 inhibitors protects against LPS plus IFN-γ-stimulated inflammation by interacting with KEAP1-regulated NRF2 activation.
Effect of 2-deoxyglucose-mediated inhibition of glycolysis on migration and invasion of HTR-8/SVneo trophoblast cells.
miR-656-3p inhibits melanomas in vitro and in vivo by inducing senescence via inhibiting LMNB2.
Discovery of potent and selective PI3Kδ inhibitors bearing amino acid fragments.
Antitumor synergism between PAK4 silencing and immunogenic phototherapy of engineered extracellular vesicles.
Milk-derived exosomes carrying siRNA-KEAP1 promote diabetic wound healing by improving oxidative stress.
Elsinochrome A induces cell apoptosis and autophagy in photodynamic therapy.
Early depletion of M1 macrophages retards the progression of glucocorticoid-associated osteonecrosis of the femoral head.
FTZ polysaccharides ameliorate kidney injury in diabetic mice by regulating gut-kidney axis.
LINC00346 regulates NLRP1-mediated pyroptosis and autophagy via binding to microRNA-637 in vascular endothelium injury.
Suppression of PGE2/EP2 signaling alleviates Hirschsprung disease by upregulating p38 mitogen-activated protein kinase activity.
FTO-mediated m6A modification alleviates autoimmune uveitis by regulating microglia phenotypes via the GPC4/TLR4/NF-κB signaling axis.
Targeting Squalene Epoxidase Confers Metabolic Vulnerability and Overcomes Chemoresistance in HNSCC.
NDUFC2 deficiency exacerbates endothelial mesenchymal transformation during ischemia-reperfusion via NLRP3.
The panda-derived Lactiplantibacillus plantarum BSG201683 improves LPS-induced intestinal inflammation and epithelial barrier disruption in vitro.
Bioengineered "Molecular Glue"-Mediated Tumor-Specific Cascade Nanoreactors with Self-Destruction Ability for Enhanced Precise Starvation/Chemosynergistic Tumor Therapy.
Oridonin inhibits the occurrence and development of colorectal cancer by reversing the Warburg effect via reducing PKM2 dimer formation and preventing its entry into the nucleus.
Site-specific Atg13 methylation-mediated autophagy regulates epithelial inflammation in PM2.5-induced pulmonary fibrosis.
Comprehensive analysis and experimental validation reveal elevated CLCN4 is a promising biomarker in endometrial cancer.
The effects of Shikonin on the hypertrophic scar of rabbit ears via the TLR4/NF-κB signaling pathway.
Oat β-D-glucan ameliorates type II diabetes through TLR4/PI3K/AKT mediated metabolic axis.
A phellinus igniarius polysaccharide/chitosan-arginine hydrogel for promoting diabetic wound healing.
Selective Impact of Selenium Compounds on Two Cytokine Storm Players.
Omentin-1 induces mechanically activated fibroblasts lipogenic differentiation through pkm2/yap/pparγ pathway to promote lung fibrosis resolution.
Type I/type III IFN and related factors regulate JEV infection and BBB endothelial integrity.
Mechanical stiffness promotes skin fibrosis through Piezo1-mediated arginine and proline metabolism.
STING signaling promotes NK cell antitumor immunity and maintains a reservoir of TCF-1(+) NK cells.
Fatty acid synthesis and oxidation regulate human endoderm differentiation by mediating SMAD3 nuclear localization via acetylation.
Metformin induces ferroptosis through the Nrf2/HO-1 signaling in lung cancer.
Activation of CTNNB1 by deubiquitinase UCHL3-mediated stabilization facilitates bladder cancer progression.
Human umbilical cord-derived mesenchymal stem cells ameliorate perioperative neurocognitive disorder by inhibiting inflammatory responses and activating BDNF/TrkB/CREB signaling pathway in aged mice.
Bisphenol P and bisphenol M promote triple-negative breast cancer metastasis through activation of AKT pathways.
[Isodopharicin C inhibits NLRP3 inflammasome activation and alleviates septic shock in mice].
FGF2 Rescued Cisplatin-Injured Granulosa Cells through the NRF2-Autophagy Pathway.
VprBP/DCAF1 Triggers Melanomagenic Gene Silencing through Histone H2A Phosphorylation.
3,5,6-Trichloro-2-pyridinol confirms ototoxicity in mouse cochlear organotypic cultures and induces cytotoxicity in HEI-OC1 cells.
Mitochondrial miR-12294-5p regulated copper-induced mitochondrial oxidative stress and mitochondrial quality control imbalance by targeted inhibition of CISD1 in chicken livers.
Systems pharmacology reveals the mechanism of Astragaloside IV in improving immune activity on cyclophosphamide-induced immunosuppressed mice.
FDX1 regulates leydig cell ferroptosis mediates PM(2.5)-induced testicular dysfunction of mice.
Noradrenaline transporter PET reflects neurotoxin-induced noradrenaline level decrease in the rat hippocampus.
Sea Cucumber Peptide Alleviates Ulcerative Colitis Induced by Dextran Sulfate Sodium by Alleviating Gut Microbiota Imbalance and Regulating miR-155/SOCS1 Axis in Mice.
MicroRNA miR-223 modulates NLRP3 and Keap1, mitigating lipopolysaccharide-induced inflammation and oxidative stress in bovine mammary epithelial cells and murine mammary glands.
Inhibition of TLR4 Signaling by Isorhapontigenin Targeting of the AHR Alleviates Cerebral Ischemia/Reperfusion Injury.
Celastrol attenuates streptozotocin-induced diabetic cardiomyopathy in mice by inhibiting the ACE / Ang II / AGTR1 signaling pathway.
FUNDC1 modulates mitochondrial defects and pancreatic β-cell dysfunction under lipotoxicity.
FAT4 overexpression promotes antitumor immunity by regulating the β-catenin/STT3/PD-L1 axis in cervical cancer.
Loganin reduces diabetic kidney injury by inhibiting the activation of NLRP3 inflammasome-mediated pyroptosis.
Shikonin suppresses small cell lung cancer growth via inducing ATF3-mediated ferroptosis to promote ROS accumulation.
Chimeric antigen receptor macrophages activated through TLR4 or IFN-γ receptors suppress breast cancer growth by targeting VEGFR2.
Ferroptosis triggered by STAT1- IRF1-ACSL4 pathway was involved in radiation-induced intestinal injury.
Lnc‑RGS5 sponges miR‑542‑5p to promote FoxM1/VEGFA signaling and breast cancer cell proliferation.
Constitutively activated AMPKα1 protects against skeletal aging in mice by promoting bone-derived IGF-1 secretion.
Edaravone Dexborneol Alleviates Neuroinflammation by Reducing Neuroglial Cell Proliferation and Suppresses Neuronal Apoptosis/Autophagy in Vascular Dementia Rats.
Intrathecal Injection of Botulinum Toxin Type A has an Analgesic Effect in Male Rats CCI Model by Inhibiting the Activation of Spinal P2X4R.
The PRMT5 inhibitor C9 mitigates hypoxia-induced carboplatin resistance in lung cancer by inducing autophagy.
Bavachinin Ameliorates Rheumatoid Arthritis Inflammation via PPARG/PI3K/AKT Signaling Pathway.
Integrated Machine Learning and Bioinformatic Analyses Constructed a Network Between Mitochondrial Dysfunction and Immune Microenvironment of Periodontitis.
Decreasing REDD1 expression protects against high glucose-induced apoptosis, oxidative stress and inflammatory injury in podocytes through regulation of the AKT/GSK-3β/Nrf2 pathway.
Spinosin protects Neuro-2a/APP695 cells from oxidative stress damage by inactivating p38.
Brexpiprazole suppresses cell proliferation and de novo lipogenesis through AMPK/SREBP1 pathway in colorectal cancer.
PDK4 facilitates fibroblast functions and diabetic wound healing through regulation of HIF-1α protein stability and gene expression.
Placental DNA methylation analysis of selective fetal growth restriction in monochorionic twins reveals aberrant methylated CYP11A1 gene for fetal growth restriction.
Protective effect of evolocumab on Müller cells in the rat retina under hyperglycaemic and hypoxic conditions.
PM2.5 mediates mouse testis Sertoli TM4 cell damage by reducing cellular NAD().
6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio) Hexanol Inhibits Proliferation and Induces Apoptosis of Endometriosis by Regulating Glutathione S-Transferase Mu Class 4.
Metabolic reprogramming contributes to radioprotection by protein kinase Cδ.
Oocytes orchestrate protein prenylation for mitochondrial function through selective inactivation of cholesterol biosynthesis in murine species.
Resveratrol improves palmitic acid‑induced insulin resistance via the DDIT4/mTOR pathway in C2C12 cells.
Hsa_circ_0001535 inhibits the proliferation and migration of ovarian cancer by sponging miR-593-3p, upregulating PTEN expression.
SARS-COV-2 spike protein promotes RPE cell senescence via the ROS/P53/P21 pathway.
cFLIP(S) regulates alternative NLRP3 inflammasome activation in human monocytes.
Proliferation-associated 2G4 P48 is stabilized by malignant T-cell amplified sequence 1 and promotes the proliferation of head and neck squamous cell carcinoma.
The circular RNA Rap1b promotes Hoxa5 transcription by recruiting Kat7 and leading to increased Fam3a expression, which inhibits neuronal apoptosis in acute ischemic stroke.
High frequency of alternative splicing variants of the oncogene Focal Adhesion Kinase in neuroendocrine tumors of the pancreas and breast.
The protective role of shenqi compound in type 2 diabetes: A comprehensive investigation of pancreatic β-cell function and mass.
Neuroprotection of NSC Therapy is Superior to Glibenclamide in Cardiac Arrest-Induced Brain Injury via Neuroinflammation Regulation.
Discovery of small molecule β-catenin suppressors that enhance immunotherapy.
Transgenic mice producing the trans 10, cis 12-conjugated linoleic acid present reduced adiposity and increased thermogenesis and fibroblast growth factor 21 (FGF21).
Pterostilbene participates in TLR4- mediated inflammatory response and autophagy-dependent Aβ(1-42) endocytosis in Alzheimer's disease.
TCFL5 knockdown sensitizes DLBCL to doxorubicin treatment via regulation of GPX4.
LGR4 promotes tumorigenesis by activating TGF-β1/Smad signaling pathway in multiple myeloma.
Mechanism of the HIF-1α/VEGF/VEGFR-2 pathway in the proliferation and apoptosis of human haemangioma endothelial cells.
The polyA tail facilitates splicing of last introns with weak 3' splice sites via PABPN1.
The GLI2/CDH6 axis enhances migration, invasion and mitochondrial fission of stomach adenocarcinoma cells.
Clinical significance and immune infiltration analyses of a novel coagulation-related signature in ovarian cancer.
A network pharmacology approach to investigate dehydrocostus lactone inhibits the proliferation and epithelial-mesenchymal transition of human gastric cancer cells via regulating the PI3K/Akt and extracellular signal-regulated kinases/mitogen-activated protein kinase signalling pathways.
Discovery of tetrahydroisoquinolineindole derivatives as first dual PRMT5 inhibitors/hnRNP E1 upregulators: Design, synthesis and biological evaluation.
GSDMD promotes neutrophil extracellular traps via mtDNA-cGAS-STING pathway during lung ischemia/reperfusion.
Broad-spectrum vaccine via combined immunization routes triggers potent immunity to SARS-CoV-2 and its variants.
Primary cilia control oligodendrocyte precursor cell proliferation in white matter injury via Hedgehog-independent CREB signaling.
Virus-induced lncRNA-BTX allows viral replication by regulating intracellular translocation of DHX9 and ILF3 to induce innate escape.
NLRP3 Inflammasome Activates Endothelial-to-Mesenchymal Transition via Focal Adhesion Kinase Pathway in Bleomycin-Induced Pulmonary Fibrosis.
Activation of NLRP3 Inflammasome via Drp1 Overexpression in Kupffer Cells Aggravates Ischemia-reperfusion Injury in Hepatic Steatosis.
TiO(2) nanoparticles promote tumor metastasis by eliciting pro-metastatic extracellular vesicles.
Metabolism-associated molecular classification of cervical cancer.
Circular RNA P4HB promotes glycolysis and tumor progression by binding with PKM2 in lung adenocarcinoma.
Identification of Novel Targeting Sites of Calcineurin and CaMKII in Human Ca(V)3.2 T-Type Calcium Channel.
The Dual-Mode Transition of Myofibroblasts Derived from Hepatic Stellate Cells in Liver Fibrosis.
Acteoside protects podocyte against apoptosis through regulating AKT/GSK-3β signaling pathway in db/db mice.
Global lactylome reveals lactylation-dependent mechanisms underlying T(H)17 differentiation in experimental autoimmune uveitis.
TCAF2 is associated with the immune microenvironment, promotes pathogenesis, and impairs prognosis in glioma.
Butyrate prevents visceral adipose tissue inflammation and metabolic alterations in a Friedreich's ataxia mouse model.
ER-associated degradation in cystinosis pathogenesis and the prospects of precision medicine.
The effect of acupuncture on lateral habenular nucleus and intestinal microflora in depression model rats.
FDCA Attenuates Neuroinflammation and Brain Injury after Cerebral Ischemic Stroke.
A Study of Gentianae Radix et Rhizoma Class Differences Based on Chemical Composition and Core Efficacy.
The mitochondrial fusion-associated protein MFN2 can be used as a novel prognostic molecule for clear cell renal cell carcinoma.
Integrated single-cell and bulk RNA sequencing in pancreatic cancer identifies disulfidptosis-associated molecular subtypes and prognostic signature.
Afzelin protects against doxorubicin-induced cardiotoxicity by promoting the AMPKα/SIRT1 signaling pathway.
Dendrobium officinale polysaccharide Converts M2 into M1 Subtype Macrophage Polarization via the STAT6/PPAR-r and JAGGED1/NOTCH1 Signaling Pathways to Inhibit Gastric Cancer.
Fermented cordyceps powder alleviates silica-induced pulmonary inflammation and fibrosis in rats by regulating the Th immune response.
RFC2 promotes aerobic glycolysis and progression of colorectal cancer.
miR-379-5P INHIBITION ENHANCES INTESTINAL EPITHELIAL PROLIFERATION AND BARRIER FUNCTION RECOVERY AFTER ISCHEMIA/REPERFUSION BY TARGETING EIF4G2.
ANNEXIN A2 FACILITATES NEOVASCULARIZATION TO PROTECT AGAINST MYOCARDIAL INFARCTION INJURY VIA INTERACTING WITH MACROPHAGE YAP AND ENDOTHELIAL INTEGRIN Β3.
Inhibition of miR-543 alleviates cardiac fibroblast-to-myofibroblast transformation and collagen expression in insulin resistance via targeting PTEN.
Oral administration of sophoricoside (SOP) inhibits neuronal damage and neuroinflammation to curb neurodegeneration in Parkinson's disease.
MiR-21-3p in extracellular vesicles from vascular fibroblasts of spontaneously hypertensive rat promotes proliferation and migration of vascular smooth muscle cells.
Generation and application of a novel transgenic zebrafish line Tg(GAcyp1a:eGFP/Luc) as an in vivo assay to sensitive and specific monitoring of DLCs in the environment.
Polydopamine-loaded prunetin nanomaterials activate DRD2 to reduce UV-induced inflammation by stabilizing and promoting Nrf2 nuclear translocation.
FUT8-Mediated Core Fucosylation Promotes the Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension.
Clearance of Stress-Induced Premature Senescent Cells Alleviates the Formation of Abdominal Aortic Aneurysms.
Overexpression of RACGAP1 by E2F1 Promotes Neuroendocrine Differentiation of Prostate Cancer by Stabilizing EZH2 Expression.
Protective effect of GLP-1 analog liraglutide on podocytes in mice with diabetic nephropathy.
Paternal lipopolysaccharide exposure induced intrauterine growth restriction via the inactivation of placental MEST/PI3K/AKT pathway in mice.
Mannan-binding lectin ameliorates renal fibrosis by suppressing macrophage-to-myofibroblast transition.
Network pharmacology and in vivo studies reveal the neuroprotective effects of paeoniflorin on Alzheimer's disease.
Nicotine plays a protective role in rats with induced viral pneumonia with polyinosinic-polycytidylic acid through α7nAChR.
Global m6A methylation and gene expression patterns in human microglial HMC3 cells infected with HIV-1.
BTK inhibition potentiates anti-PD-L1 treatment in murine melanoma: potential role for MDSC modulation in immunotherapy.
Local administration of liposomal-based Plekhf1 gene therapy attenuates pulmonary fibrosis by modulating macrophage polarization.
Protective effect of benzaldehyde combined with albendazole against brain injury induced by Angiostrongylus cantonensis infection in mice.
Catalpol Alleviates Ischemic Stroke Through Promoting Angiogenesis and Facilitating Proliferation and Differentiation of Neural Stem Cells via the VEGF-A/KDR Pathway.
Tanshinone IIA confers protection against myocardial ischemia/reperfusion injury by inhibiting ferroptosis and apoptosis via VDAC1.
Ligustrazine and liguzinediol protect against doxorubicin-induced cardiomyocytes injury by inhibiting mitochondrial apoptosis and autophagy.
Aucubin alleviates methotrexate-induced enteritis in rats by inducing autophagy.
Influences of lysine-specific demethylase 1 inhibitors on NO synthase-Kruppel-like factor pathways in human endothelial cells in vitro and zebrafish (Danio rerio) larvae in vivo.
The ASH1L-AS1-ASH1L axis controls NME1-mediated activation of the RAS signaling in gastric cancer.
mTOR/ULK1 signaling axis mediated ultrashort wave regulation of autophagy to alleviate diabetic kidney disease.
Integrated network pharmacology to investigate the mechanism of Salvia miltiorrhiza Bunge in the treatment of myocardial infarction.
Avicularin alleviates acute liver failure by regulation of the TLR4/MyD88/NF-κB and Nrf2/HO-1/GPX4 pathways to reduce inflammation and ferroptosis.
Macrophage-derived inflammation promotes pulmonary vascular remodeling in hypoxia-induced pulmonary arterial hypertension mice.
PCSK9 promotes tumor cell proliferation and migration by facilitating CCL25 secretion in esophageal squamous cell carcinoma.
FOXO1 promotes endothelial cell elongation and angiogenesis by up-regulating the phosphorylation of myosin light chain 2.
Uterine Fluid Extracellular Vesicles Proteome Is Altered During the Estrous Cycle.
Cucurbitacin C suppresses the progression of pancreatic ductal adenocarcinoma via inhibition of the cGMP-PKG-VASP axis.
Molecular basis of inherited protein C deficiency results from genetic variations in the signal peptide and propeptide regions.
Antidepressant effects of 70% ethanolic extract of Lonicerae japonicae flos and it contained chlorogenic acid via upregulation of BDNF-TrkB pathway in the hippocampus of mice.
Hyaluronan-CD44 Interaction Regulates Mouse Retinal Progenitor Cells Migration, Proliferation and Neuronal Differentiation.
A Responsive Nanorobot Modulates Intracellular Zinc Homeostasis to Amplify Mitochondria-Targeted Phototherapy.
CDN1163, an activator of sarco/endoplasmic reticulum Ca(2+) ATPase, up-regulates mitochondrial functions and protects against lipotoxicity in pancreatic β-cells.
Peanut skin procyanidins reduce intestinal glucose transport protein expression, regulate serum metabolites and ameliorate hyperglycemia in diabetic mice.
Effects of HMGB1/RAGE/cathespin B inhibitors on alleviating hippocampal injury by regulating microglial pyroptosis and caspase activation in neonatal hypoxic-ischemic brain damage.
Ginkgolic acid inhibits the replication of pseudorabies virus in vitro and in vivo by suppressing the transcription of viral late genes.
Anti-resorption role of low-intensity pulsed ultrasound (LIPUS) during large-scale bone reconstruction using porous titanium alloy scaffolds through inhibiting osteoclast differentiation.
A positive feedback loop between miR-574-3p and HIF-1α in promoting angiogenesis under hypoxia.
New insights into the effect of VMP1 on the treatment of pressure overload-induced pathological cardiac hypertrophy: Involving SERCA-regulated autophagic flux.
Characterization of STING from common carp (Cyprinus carpio L.) involved in spring viremia of carp virus infection.
Design, synthesis and biological evaluation of 4-arylamino-pyrimidine derivatives as focal adhesion kinase inhibitors.
Chitosan biomaterial enhances the effect of OECs on the inhibition of sciatic nerve injury-induced neuropathic pain.
A natural sesquiterpene lactone isolinderalactone attenuates lipopolysaccharide-induced inflammatory response and acute lung injury through inhibition of NF-κB pathway and activation Nrf2 pathway in macrophages.
CTRP6 regulates M1 macrophage polarization via the PPAR-γ/NF-κB pathway and reprogramming glycolysis in recurrent spontaneous abortion.
Escin avoids hemorrhagic transformation in ischemic stroke by protecting BBB through the AMPK/Cav-1/MMP-9 pathway.
Kaempferol ameliorated alcoholic liver disease through inhibiting hepatic bile acid synthesis by targeting intestinal FXR-FGF15 signaling.
Engineering high-affinity dual targeting cellular nanovesicles for optimised cancer immunotherapy.
Oxytocin alleviates cognitive and memory impairments by decreasing hippocampal microglial activation and synaptic defects via OXTR/ERK/STAT3 pathway in a mouse model of sepsis-associated encephalopathy.
Whey protein peptides PEW and LLW synergistically ameliorate hyperuricemia and modulate gut microbiota in potassium oxonate and hypoxanthine-induced hyperuricemic rats.
Aryl hydrocarbon receptor regulates IL-22 receptor expression on thymic epithelial cell and accelerates thymus regeneration.
Transcriptomic Profiling Reveals Claudin 18.2 as a Diagnostic Biomarker of Ménétrier's Disease and the Role of Hedgehog Signaling in Pathogenesis.
Platycodin D inhibits glioblastoma cell proliferation, migration, and invasion by regulating DEPDC1B-mediated epithelial-to-mesenchymal transition.
Quercetin Attenuates the Combined Effects of Zearalenone and Lipopolysaccharide on IPEC-J2 Cell Injury through Activating the Nrf2 Signaling Pathway.
Plumbagin has an inhibitory effect on the growth of TSCC PDX model and it enhances the anticancer efficacy of cisplatin.
Porcine promyelocytic leukemia protein isoforms suppress Japanese encephalitis virus replication in PK15 cells.
Inhibiting G6PD by quercetin promotes degradation of EGFR T790M mutation.
Osteopontin enhances the effect of treadmill training and promotes functional recovery after spinal cord injury.
Dopaminergic Projections from the Hypothalamic A11 Nucleus to the Spinal Trigeminal Nucleus Are Involved in Bidirectional Migraine Modulation.
Schwann Cell-Derived Exosomes and Methylprednisolone Composite Patch for Spinal Cord Injury Repair.
miR-196a Promotes Proliferation of Mammary Epithelial Cells by Targeting CDKN1B.
PDK4 rescues high-glucose-induced senescent fibroblasts and promotes diabetic wound healing through enhancing glycolysis and regulating YAP and JNK pathway.
ACO2 deficiency increases vulnerability to Parkinson's disease via dysregulating mitochondrial function and histone acetylation-mediated transcription of autophagy genes.
Role of DCLK1/Hippo pathway in type II alveolar epithelial cells differentiation in acute respiratory distress syndrome.
Circular RNA ZBTB46 depletion alleviates the progression of Atherosclerosis by regulating the ubiquitination and degradation of hnRNPA2B1 via the AKT/mTOR pathway.
DJ1 Ameliorates AD-like Pathology in the Hippocampus of APP/PS1 Mice.
Role of the p38/AKT Pathway in the Promotion of Cell Proliferation by Serum Heat Inactivation.
BCAS2 Participates in Insulin Synthesis and Secretion via mRNA Alternative Splicing in Mice.
Attenuation of estrogen and its receptors in the post-menopausal stage exacerbates dyslipidemia and leads to cognitive impairment.
PHB2 Alleviates Neurotoxicity of Prion Peptide PrP(106-126) via PINK1/Parkin-Dependent Mitophagy.
TRPV4 enhances the synthesis of fatty acids to drive the progression of ovarian cancer through the calcium-mTORC1/SREBP1 signaling pathway.
Inhibition of Hsp110-STAT3 interaction in endothelial cells alleviates vascular remodeling in hypoxic pulmonary arterial Hypertension model.
WGX50 mitigates doxorubicin-induced cardiotoxicity through inhibition of mitochondrial ROS and ferroptosis.
Crucial role of hsa-mir-503, hsa-mir-1247, and their validation in prostate cancer.
LCMR1 Promotes Large-Cell Lung Cancer Proliferation and Metastasis by Downregulating HLA-Encoding Genes.
Tripartite motif 31 drives gastric cancer cell proliferation and invasion through activating the Wnt/β-catenin pathway by regulating Axin1 protein stability.
The protective effects of uric acid against myocardial ischemia via the Nrf2 pathway.
Genetic Ablation of GIGYF1, Associated With Autism, Causes Behavioral and Neurodevelopmental Defects in Zebrafish and Mice.
BSHXF-medicated serum combined with ADSCs regulates the TGF-β1/Smad pathway to repair oxidatively damaged NPCs and its component analysis.
Discovery of novel flavonoid-based CDK9 degraders for prostate cancer treatment via a PROTAC strategy.
Curcumin enhances elvitegravir concentration and alleviates oxidative stress and inflammatory response.
Pathological roles of bone marrow adipocyte-derived monocyte chemotactic protein-1 in type 2 diabetic mice.
GSK2656157, a PERK Inhibitor, Alleviates Pyroptosis of Macrophages Induced by Mycobacterium Bacillus Calmette-Guerin Infection.
Circ_16601 facilitates Hippo pathway signaling via the miR-5580-5p/FGB axis to promote my-CAF recruitment in the TME and LUAD progression.
High expression of CDKN2A is associated with poor prognosis in colorectal cancer and may guide PD-1-mediated immunotherapy.
Peptidome analysis reveals critical roles for peptides in a rat model of intestinal ischemia/reperfusion injury.
Green Pea (Pisum sativum L.) Hull Polyphenol Extract Alleviates NAFLD through VB6/TLR4/NF-κB and PPAR Pathways.
NF-κB c-Rel Is a Potential Therapeutic Target for Acute Corneal Transplant Rejection.
Cholesterol mediated ferroptosis suppression reveals essential roles of Coenzyme Q and squalene.
The HDAC inhibitor HFY-4A improves TUSC2 transcription to induce immunogenic cell death in breast cancer.
ADAR1 affects gastric cancer cell metastasis and reverses cisplatin resistance through AZIN1.
Tert-butyl hydroperoxide induces ferroptosis of bone mesenchymal stem cells by repressing the prominin2/BACH1/ROS axis.
CAB39 promotes cisplatin resistance in bladder cancer via the LKB1-AMPK-LC3 pathway.
5-(3',4'-dihydroxyphenyl)-γ-valerolactone, a microbiota metabolite of flavan-3-ols, activates SIRT1-mediated autophagy to attenuate H₂O₂-induced inhibition of osteoblast differentiation in MC3T3-E1 cells.
A phosphoglycerate mutase 1 allosteric inhibitor overcomes drug resistance to EGFR-targeted therapy via disrupting IL-6/JAK2/STAT3 signaling pathway in lung adenocarcinoma.
TREM2 Inhibits Tau Hyperphosphorylation and Neuronal Apoptosis via the PI3K/Akt/GSK-3β Signaling Pathway In vivo and In vitro.
Zika virus replication on endothelial cells and invasion into the central nervous system by inhibiting interferon β translation.
Endothelial Arid1a deletion disrupts the balance among angiogenesis, neurogenesis and gliogenesis in the developing brain.
Suprabasin enhances the invasion, migration, and angiogenic ability of oral squamous cell carcinoma cells under hypoxic conditions.
HSF4 promotes tumor progression of colorectal cancer by transactivating c-MET.
Remote Ischemic Conditioning Relieves Necrotizing Enterocolitis Through Regulation of Redox and Inflammation.
Sirt1 protects against intervertebral disc degeneration induced by 1,25-dihydroxyvitamin D insufficiency in mice by inhibiting the NF-κB inflammatory pathway.
Mesenchymal stem cells ameliorate cisplatin-induced acute kidney injury via let-7b-5p.
Thalamocortical Circuit Controls Neuropathic Pain via Up-regulation of HCN2 in the Ventral Posterolateral Thalamus.
AdipoRon mitigates tau pathology and restores mitochondrial dynamics via AMPK-related pathway in a mouse model of Alzheimer's disease.
CircRNA_0017076 acts as a sponge for miR-185-5p in the control of epithelial-to-mesenchymal transition of tubular epithelial cells during renal interstitial fibrosis.
BAP18 facilitates CTCF-mediated chromatin accessible to regulate enhancer activity in breast cancer.
miR-27a-3p relieves heat stress-induced mitochondrial damage and aberrant milk protein synthesis through MEK/ERK pathway in BMECs.
Methionine alleviates heat stress-induced ferroptosis in bovine mammary epithelial cells through the Nrf2 pathway.
SEL1L-HRD1 endoplasmic reticulum-associated degradation controls STING-mediated innate immunity by limiting the size of the activable STING pool.
Neutrophil membrane-camouflaged nanoparticles alleviate inflammation and promote angiogenesis in ischemic myocardial injury.
Irisin attenuates fine particulate matter induced acute lung injury by regulating Nod2/NF-κB signaling pathway.
Lyn attenuates sepsis-associated acute kidney injury by inhibition of phospho-STAT3 and apoptosis.
The Bcr-Abl inhibitor DCC-2036 inhibits necroptosis and ameliorates osteoarthritis by targeting RIPK1 and RIPK3 kinases.
Identification of MAP Kinase Kinase 3 as a protein target of myricetin in non-small cell lung cancer cells.
Ribosomal protein L32 enhances hepatocellular carcinoma progression.
Hypoxia disrupts the nasal epithelial barrier by inhibiting PTPN2 in chronic rhinosinusitis with nasal polyps.
Lipin2 ameliorates diabetic encephalopathy via suppressing JNK/ERK-mediated NLRP3 inflammasome overactivation.
Aescin can alleviate NAFLD through Keap1-Nrf2 by activating antioxidant and autophagy.
Jiang-Tang-San-Huang pill alleviates type 2 diabetes mellitus through modulating the gut microbiota and bile acids metabolism.
P4HA1 activates HMGCS1 to promote nasopharyngeal carcinoma ferroptosis resistance and progression.
Autophagy ameliorates Pseudomonas aeruginosa-infected diabetic wounds by regulating the toll-like receptor 4/myeloid differentiation factor 88 pathway.
MC1R Peptide Agonist Self-Assembles into a Hydrogel That Promotes Skin Pigmentation for Treating Vitiligo.
RNA N6-methyladenosine reader IGF2BP3 interacts with MYCN and facilitates neuroblastoma cell proliferation.
Sp1 promotes tumour progression by remodelling the mitochondrial network in cervical cancer.
Nicaraven protects against endotoxemia-induced inflammation and organ injury through modulation of AMPK/Sirt1 signaling in macrophages.
Colocalization of Chikungunya Virus with Its Receptor MXRA8 during Cell Attachment, Internalization, and Membrane Fusion.
Lactoferrin Relieves Deoxynivalenol-Induced Oxidative Stress and Inflammatory Response by Modulating the Nrf2/MAPK Pathways in the Liver.
The effect of epigenetic reprogramming using MI192 HDAC inhibitor on enhancing the osteogenesis of human adipose-derived stem cells in vitro.
E7050 Suppresses the Growth of Multidrug-Resistant Human Uterine Sarcoma by Inhibiting Angiogenesis via Targeting of VEGFR2-Mediated Signaling Pathways.
Gasdermin D Plays an Oncogenic Role in Glioma and Correlates to an Immunosuppressive Microenvironment.
Identification of an LDLR variant in a Chinese familial hypercholesterolemia and its relation to ROS/NLRP3-Mediated pyroptosis in hepatic cells.
LEM Domain Containing 1 Acts as a Novel Oncogene and Therapeutic Target for Triple-Negative Breast Cancer.
QiShenYiQi dripping pill alleviates myocardial ischemia-induced ferroptosis via improving mitochondrial dynamical homeostasis and biogenesis.
Wei-Tong-Xin ameliorated cisplatin-induced mitophagy and apoptosis in gastric antral mucosa by activating the Nrf2/HO-1 pathway.
Benzothiazole Substitution Analogs of Rhodacyanine Hsp70 Inhibitors Modulate Tau Accumulation.
Role of Protein Tyrosine Phosphatase 1B Inhibitor in Early Brain Injury of Subarachnoid Hemorrhage in Mice.
Mitophagy associated self-degradation of phosphorylated MAP4 guarantees the migration and proliferation responses of keratinocytes to hypoxia.
A New Method for Programmable RNA Editing Using CRISPR Effector Cas13X.1.
Impact of age on the rotenone-induced sporadic Parkinson's disease model using Drosophila melanogaster.
Knock-down of PGM1 inhibits cell viability, glycolysis, and oxidative phosphorylation in glioma under low glucose condition via the Myc signaling pathway.
Mutation-Driven S100A8 Overexpression Confers Aberrant Phenotypes in Type 1 CALR-Mutated MPN.
Vitamin D receptor attenuate ischemia-reperfusion kidney injury via inhibiting ATF4.
Yishen Tongluo formula alleviates diabetic kidney disease through regulating Sirt6/TGF-β1/Smad2/3 pathway and promoting degradation of TGF-β1.
Mitochondria-Targeted Nanosystem Enhances Radio-Radiodynamic-Chemodynamic Therapy on Triple Negative Breast Cancer.
JNK-JUN-NCOA4 axis contributes to chondrocyte ferroptosis and aggravates osteoarthritis via ferritinophagy.
A novel candidate gene CLN8 regulates fat deposition in avian.
The circadian rhythm gene Bmal1 ameliorates acute deoxynivalenol-induced liver damage.
Danlou tablet inhibits high-glucose-induced cardiomyocyte apoptosis via the miR-34a-SIRT1 axis.
Electroacupuncture alleviates early brain injury via modulating microglia polarization and suppressing neuroinflammation in a rat model of subarachnoid hemorrhage.
Farnesoid X Receptor (FXR) Regulates mTORC1 Signaling and Autophagy by Inhibiting SESN2 Expression.
Regulation of telomere silencing by the core histones-autophagy-Sir2 axis.
Trans-gnetin H isolated from the seeds of Paeonia species induces autophagy via inhibiting mTORC1 signalling through AMPK activation.
Myricetin improves apoptosis after ischemic stroke via inhibiting MAPK-ERK pathway.
Progressive degeneration of the retina in Loxl3 mutant mouse model of Stickler syndrome.
TGF-β Signaling Activation Confers Anlotinib Resistance in Gastric Cancer.
BNIP3-mediated autophagy via the mTOR/ULK1 pathway induces primordial follicle loss after ovarian tissue transplantation.
PbO nanoparticles increase the expression of ICAM-1 and VCAM-1 by increasing reactive oxygen species production in choroid plexus.
The role of selenoprotein M in nickel-induced pyroptosis in mice spleen tissue via oxidative stress.
The Rab GTPase-binding protein EHBP1L1 and its interactors CD2AP/CIN85 negatively regulate the length of primary cilia via actin remodeling.
The well-developed actin cytoskeleton and Cthrc1 expression by actin-binding protein drebrin in myofibroblasts promote cardiac and hepatic fibrosis.
Zebrafish Galectin 3 binding protein is the target antigen of the microglial 4C4 monoclonal antibody.
LncRNA FRMD6-AS1 promotes hepatocellular carcinoma cell migration and stemness by regulating SENP1/HIF-1α axis.
Decreased AGGF1 facilitates the progression of placenta accreta spectrum via mediating the P53 signaling pathway under the regulation of miR-1296-5p.
CEMIP promotes small cell lung cancer proliferation by activation of glutamine metabolism via FBXW7/c-Myc-dependent axis.
Sirt3-dependent regulation of mitochondrial oxidative stress and apoptosis contributes to the dysfunction of pancreatic islets after severe burns.
Porcine reproductive and respiratory syndrome virus infection triggers autophagy via ER stress-induced calcium signaling to facilitate virus replication.
Neuroprotective effects of neural stem cells pretreated with neuregulin1β on PC12 cells exposed to oxygen-glucose deprivation/reoxygenation.
Myocardial ischemia-reperfusion injury is probably due to the excessive production of mitochondrial ROS caused by the activation of 5-HT degradation system mediated by PAF receptor.
LncRNA UCA1 promoted cisplatin resistance in lung adenocarcinoma with HO1 targets NRF2/HO1 pathway.
Immunity-related long noncoding RNA WDFY3-AS2 inhibited cell proliferation and metastasis through Wnt/β-catenin signaling in oral squamous cell carcinoma.
Decreasing GDF15 Promotes Inflammatory Signals and Neutrophil Infiltration in Psoriasis Models.
Neuroprotective effect of a Keap1-Nrf2 Protein-Protein Inter-action inhibitor on cerebral Ischemia/Reperfusion injury.
Determination of the optimal concentration and duration of C5aR antagonist application in an inflammatory model of human dental pulp cells.
ROS-activated MAPK/ERK pathway regulates crosstalk between Nrf2 and Hif-1α to promote IL-17D expression protecting the intestinal epithelial barrier under hyperoxia.
Tiliroside targets TBK1 to induce ferroptosis and sensitize hepatocellular carcinoma to sorafenib.
CHD1 deletion stabilizes HIF1α to promote angiogenesis and glycolysis in prostate cancer.
iPSC-based modeling of THD recapitulates disease phenotypes and reveals neuronal malformation.
Long-term Pu-erh tea consumption improves blue light-induced depression-like behaviors.
Semaglutide inhibits ischemia/reperfusion-induced cardiomyocyte apoptosis through activating PKG/PKCε/ERK1/2 pathway.
DNA replication initiation factor RECQ4 possesses a role in antagonizing DNA replication initiation.
Deletion of LCMR1 in alveolar type II cells induces lethal impairment of lung structure and function in adult mice.
LncRNA SLC25A21-AS1 increases the chemosensitivity and inhibits the progression of ovarian cancer by upregulating the expression of KCNK4.
The RNA-binding protein hnRNP F is required for the germinal center B cell response.
The NLRP3 inflammasome recognizes alpha-2 and alpha-7.3 giardins and decreases the pathogenicity of Giardia duodenalis in mice.
NPAS2 promotes aerobic glycolysis and tumor growth in prostate cancer through HIF-1A signaling.
Pseurotin A Validation as a Metastatic Castration-Resistant Prostate Cancer Recurrence-Suppressing Lead via PCSK9-LDLR Axis Modulation.
Cuproptosis is involved in copper-induced hepatotoxicity in chickens.
SP1 transcriptionally regulates UBE2N expression to promote lung adenocarcinoma progression.
A novel feedback regulated loop of circRRM2-IGF2BP1-MYC promotes breast cancer metastasis.
Inhibition of miR-4640-5p alleviates pulmonary hypertension in chronic obstructive pulmonary disease patients by regulating nitric oxide synthase 1.
Isoginkgetin-loaded reactive oxygen species scavenging nanoparticles ameliorate intervertebral disc degeneration via enhancing autophagy in nucleus pulposus cells.
PPARα Inhibits Astrocyte Inflammation Activation by Restoring Autophagic Flux after Transient Brain Ischemia.
PDCD6 Promotes Hepatocellular Carcinoma Cell Proliferation and Metastasis through the AKT/GSK3β/β-catenin Pathway.
Chlorogenic acid combined with epigallocatechin-3-gallate mitigates D-galactose-induced gut aging in mice.
Human umbilical cord mesenchymal stem cells conditioned medium exerts anti-tumor effects on KGN cells in a cell density-dependent manner through activation of the Hippo pathway.
Swimming training combined with fecal microbial transplantation protects motor functions in rats with spinal cord injury by improving the intestinal system.
Possible mechanisms associated with immune escape and apoptosis on anti-hepatocellular carcinoma effect of Mu Ji Fang granules.
Curcumin-dependent phenotypic transformation of microglia mediates resistance to pseudorabies-induced encephalitis.
Atf4 regulates angiogenic differences between alveolar bone and long bone macrophages by regulating M1 polarization, based on single-cell RNA sequencing, RNA-seq and ATAC-seq analysis.
Near-Infrared Phototheranostic Iron Pyrite Nanocrystals Simultaneously Induce Dual Cell Death Pathways via Enhanced Fenton Reactions in Triple-Negative Breast Cancer.
Supplemental Clostridium butyricum modulates lipid metabolism by reshaping the gut microbiota composition and bile acid profile in IUGR suckling piglets.
Phosphoglycerate dehydrogenase activates PKM2 to phosphorylate histone H3T11 and attenuate cellular senescence.
IFN-γ Facilitates Corneal Epithelial Cell Pyroptosis Through the JAK2/STAT1 Pathway in Dry Eye.
m(6)A reader HNRNPA2B1 destabilization of ATG4B regulates autophagic activity, proliferation and olaparib sensitivity in breast cancer.
A network pharmacology approach and experimental validation to investigate the anticancer mechanism and potential active targets of ethanol extract of Wei-Tong-Xin against colorectal cancer through induction of apoptosis via PI3K/AKT signaling pathway.
Zearalenone induces oxidative stress and autophagy in goat Sertoli cells.
Lysosome-related exosome secretion mediated by miR-26b / Rab31 pathway was associated with the proliferation and migration of MCF-7 cells treated with BPA.
A novel circular RNA circNLRP3 alleviated ricin toxin-induced TNF-α production through sponging miR-221-5p.
ROS-responsive magnesium-containing microspheres for antioxidative treatment of intervertebral disc degeneration.
25-hydroxycholesterol inhibits human papillomavirus infection in cervical epithelial cells by perturbing cytoskeletal remodeling.
Histone mRNA polyadenylation-mediated inflammation underlies various virus infections and cancers.
HTRA1 from OVX rat osteoclasts causes detrimental effects on endplate chondrocytes through NF-κB.
AQP8 may affect glioma proliferation and growth by regulating GSK-3β phosphorylation and nuclear transport of β-catenin.
miR-484 mediates oxidative stress-induced ovarian dysfunction and promotes granulosa cell apoptosis via SESN2 downregulation.
Targeting hexokinase 1 alleviates NLRP3-mediated inflammation in apical periodontitis: A laboratory investigation.
The role of CNPY2 in endothelial injury and inflammation during the progress of atherosclerosis.
Bach1 modulates AKT3 transcription to participate in hyperglycaemia-mediated EndMT in vascular endothelial cells.
Effects of long-term resveratrol treatment in hypothalamic astrocyte cultures from aged rats.
Efficacy of Danggui Buxue decoction on diabetic nephropathy-induced renal fibrosis in rats and possible mechanism.
Photodynamic therapy enhances the cytotoxicity of temozolomide against glioblastoma via reprogramming anaerobic glycolysis.
ARHGAP44 expression is associated with the metastasis of osteosarcoma and is a promising prognostic biomarker.
Glycoside combinations of Buyang Huanwu decoction ameliorate atherosclerosis via STAT3, HIF-1, and VEGF.
Naringin regulates endoplasmic reticulum stress and mitophagy through the ATF3/PINK1 signaling axis to alleviate pulmonary fibrosis.
Resveratrol and Dulaglutide ameliorate adiposity and liver dysfunction in rats with diet-induced metabolic syndrome: Role of SIRT-1 / adipokines / PPARγ and IGF-1.
Combined Application of Exosomes and FPR2 Agonist LXA4 in Controlling Fetal Membrane Inflammation and Promoting Fetal Membrane Tissue Repair.
Developmental growth plate cartilage formation suppressed by artificial light at night via inhibiting BMAL1-driven collagen hydroxylation.
TRIM7 inhibits encephalomyocarditis virus replication by activating interferon-β signaling pathway.
The molecular mechanism of miR-96-5p in the pathogenesis and treatment of polycystic ovary syndrome.
Promotion of intestinal epithelial cell apoptosis by enterotoxigenic Escherichia coli via PKA-mediated inhibition of mTORC1 activation.
Bone microenvironment regulative hydrogels with ROS scavenging and prolonged oxygen-generating for enhancing bone repair.
Anti-inflammatory labdane diterpenoids from the aerial parts of Leonurus japonicus.
Jinyinqingre Oral Liquid alleviates LPS-induced acute lung injury by inhibiting the NF-κB/NLRP3/GSDMD pathway.
Toosendanin-induced apoptosis of CMT-U27 is mediated through the mitochondrial apoptotic pathway.
Schisandrin B Improves the Hypothermic Preservation of Celsior Solution in Human Umbilical Cord Mesenchymal Stem Cells.
Chromatin remodeling and nucleoskeleton synergistically control osteogenic differentiation in different matrix stiffnesses.
Synergistic effects of combined treatment of 1,2-dichloroethane and high-dose ethanol on liver damage in mice and the related mechanisms.
Comprehensive analysis of lncRNA-mRNA co-expression networks in HPV-driven cervical cancer reveals the pivotal function of LINC00511-PGK1 in tumorigenesis.
Alleviating experimental pulmonary hypertension via co-delivering FoxO1 stimulus and apoptosis activator to hyperproliferating pulmonary arteries.
The role of 14-3-3 in the progression of vascular inflammation induced by lipopolysaccharide.
MED27 plays a tumor-promoting role in breast cancer progression by targeting KLF4.
Deciphering the molecular mechanism of the THBS1 gene in the TNF signaling axis in glioma stem cells.
Visceral adipose tissue-directed human kallistatin gene therapy improves adipose tissue remodeling and metabolic health in obese mice.
Targeting lncRNA DDIT4-AS1 Sensitizes Triple Negative Breast Cancer to Chemotherapy via Suppressing of Autophagy.
Role of FLCN Phosphorylation in Insulin-Mediated mTORC1 Activation and Tumorigenesis.
ERK Inhibition Promotes Engraftment of Allografts by Reprogramming T-Cell Metabolism.
Autonomous metal-organic framework nanorobots for active mitochondria-targeted cancer therapy.
Construction and Characterization of Immortalized Fibroblast Cell Line from Bactrian Camel.
MiR-145 regulates steroidogenesis in mouse primary granulosa cells by targeting Arpc5 and subsequent cytoskeleton remodeling.
Potential Mechanisms of Metformin-Induced Apoptosis in HeLa Cells.
Platycodin D suppresses proliferation, migration, and invasion of human glioblastoma cells through regulation of Skp2.
Exercise reduces hyperlipidemia-induced cardiac damage in apolipoprotein E-deficient mice via its effects against inflammation and oxidative stress.
The p23 co-chaperone is a succinate-activated COX-2 transcription factor in lung adenocarcinoma tumorigenesis.
Silencing of AJAP1 expression by promoter methylation activates the Wnt/β-catenin signaling pathway to promote tumor proliferation and metastasis in salivary adenoid cystic carcinoma.
Mechanism of Yiqi Huoxue Huatan recipe in the treatment of coronary atherosclerotic disease through network pharmacology and experiments.
TMEM41B Is an Interferon-Stimulated Gene That Promotes Pseudorabies Virus Replication.
Peptidomics Analysis Reveals the Buccal Gland of Jawless Vertebrate Lamprey as a Source of Multiple Bioactive Peptides.
Annao Pingchong decoction alleviate the neurological impairment by attenuating neuroinflammation and apoptosis in intracerebral hemorrhage rats.
Alr Gene in Brucella suis S2: Its Role in Lipopolysaccharide Biosynthesis and Bacterial Virulence in RAW264.7.
LCK facilitates DNA damage repair by stabilizing RAD51 and BRCA1 in the nucleus of chemoresistant ovarian cancer.
EZH2 Gene Knockdown Inhibits Sheep Pituitary Cell Proliferation via Downregulating the AKT/ERK Signaling Pathway.
Protective Effect and Mechanisms of Eckol on Chronic Ulcerative Colitis Induced by Dextran Sulfate Sodium in Mice.
The Cytotoxic Cardiac Glycoside (-)-Cryptanoside A from the Stems of Cryptolepis dubia and Its Molecular Targets.
Persistent Coxsackievirus B3 Infection in Pancreatic Ductal Cells In Vitro Downregulates Cellular Polyamine Metabolism.
Bis-Benzylisoquinoline Alkaloids Inhibit Porcine Epidemic Diarrhea Virus by Disrupting Virus Entry.
Supplementing a specific synbiotic suppressed the incidence of AOM/DSS-induced colorectal cancer in mice.
SETD7 promotes lateral plate mesoderm formation by modulating the Wnt/β-catenin signaling pathway.
Mettl3-mediated m(6)A modification plays a role in lipid metabolism disorders and progressive liver damage in mice by regulating lipid metabolism-related gene expression.
Necroptosis-Related Prognostic Model for Pancreatic Carcinoma Reveals Its Invasion and Metastasis Potential through Hybrid EMT and Immune Escape.
Endothelial progenitor cell-derived exosomes inhibit pulmonary artery smooth muscle cell in vitro proliferation and resistance to apoptosis by modulating the Mitofusin-2 and Ras-Raf-ERK1/2 signaling pathway.
Kinsenoside alleviates oxidative stress-induced blood-brain barrier dysfunction via promoting Nrf2/HO-1 pathway in ischemic stroke.
Comparative analysis of two new zebrafish models: The cyp1a low-expression line and cyp1a knockout line under PAHs exposure.
Gut Microbiota Taxon-Dependent Transformation of Microglial M1/M2 Phenotypes Underlying Mechanisms of Spatial Learning and Memory Impairment after Chronic Methamphetamine Exposure.
Diosmetin Maintains Barrier Integrity by Reducing the Expression of ABCG2 in Colonic Epithelial Cells.
miR-342-5p downstream to Notch enhances arterialization of endothelial cells in response to shear stress by repressing MYC.
Acupuncture regulates the apoptosis of ovarian granulosa cells in polycystic ovarian syndrome-related abnormal follicular development through LncMEG3-mediated inhibition of miR-21-3p.
Patrinia villosa treat colorectal cancer by activating PI3K/Akt signaling pathway.
Insight into mitochondrial dysfunction mediated by clozapine-induced inhibition of PGRMC1 in PC12 cells.
Role of SIRT5 in the analgesic effectiveness of moxibustion at ST36 in mice with inflammatory pain.
Extracts from Seseli mairei Wolff attenuate imiquimod-induced psoriasis-like inflammation by inhibiting Th17 cells.
Staphylococci planktonic and biofilm environments differentially affect osteoclast formation.
Karyopherin Subunit Alpha 1 Enhances the Malignant Behaviors of Colon Cancer Cells via Promoting Nuclear Factor-κB p65 Nuclear Translocation.
Targeting the mitochondrial calcium uniporter inhibits cancer progression and alleviates cisplatin resistance in esophageal squamous cell carcinoma.
Lipophagy-mediated cholesterol synthesis inhibition is required for the survival of hepatocellular carcinoma under glutamine deprivation.
Ubiquitin ligase MARCH8 promotes the malignant progression of hepatocellular carcinoma through PTEN ubiquitination and degradation.
The histone H2B ubiquitination regulator Wac is essential for plasma cell differentiation.
Inhibition of STEAP1 ameliorates inflammation and ferroptosis of acute lung injury caused by sepsis in LPS-induced human pulmonary microvascular endothelial cells.
Aprepitant inhibits the progression of esophageal squamous cancer by blocking the truncated neurokinin‑1 receptor.
Venoarterial extracorporeal membrane oxygenation improves survival in a rat model of acute myocardial infarction.
Ginseng saponin metabolite 20(S)-protopanaxadiol relieves pulmonary fibrosis by multiple-targets signaling pathways.
Proteasomal inhibitors induce myeloma cell pyroptosis via the BAX/GSDME pathway.
PM(2.5) induces autophagy-dependent ferroptosis by endoplasmic reticulum stress in SH-SY5Y cells.
Carnitine o-octanoyltransferase is a p53 target that promotes oxidative metabolism and cell survival following nutrient starvation.
MAP2 caps tau fibrils and inhibits aggregation.
Hydrogen sulfide attenuates TMAO‑induced macrophage inflammation through increased SIRT1 sulfhydration.
Dach1 deficiency drives alveolar epithelium apoptosis in pulmonary fibrosis via modulating C-Jun/Bim activity.
Activation of pyroptosis by specific organelle-targeting photodynamic therapy to amplify immunogenic cell death for anti-tumor immunotherapy.
SIRT3-mediated autophagy contributes to ferroptosis-induced anticancer by inducing the formation of BECN1-SLC7A11 complex.
Circular RNA circ-TNRC6B inhibits the proliferation and invasion of esophageal squamous cell carcinoma cells by regulating the miR-452-5p/DAG1 axis.
Ceftriaxone improves impairments in synaptic plasticity and cognitive behavior in APP/PS1 mouse model of Alzheimer's disease by inhibiting extrasynaptic NMDAR-STEP(61) signaling.
Engineered Salmonella inhibits GPX4 expression and induces ferroptosis to suppress glioma growth in vitro and in vivo.
Diagnostic value and underlying mechanism of nasal nitric oxide in eosinophilic chronic rhinosinusitis with nasal polyps.
Effects of chronic sleep restriction on the neuro-phenotypes of Ctnnd2 knockout mice.
Glucocorticoids improve the balance of M1/M2 macrophage polarization in experimental autoimmune uveitis through the P38MAPK-MEF2C axis.
Ginkgo biloba extract attenuates cisplatin-induced renal interstitial fibrosis by inhibiting the activation of renal fibroblasts through down-regulating the HIF-1α/STAT3/IL-6 pathway in renal tubular epithelial cells.
Cannabidiol alleviates neuroinflammation and attenuates neuropathic pain via targeting FKBP5.
A Bioinspired Manganese-Organic Framework Ameliorates Ischemic Stroke through its Intrinsic Nanozyme Activity and Upregulating Endogenous Antioxidant Enzymes.
Potential effects of brain lipid binding protein in the pathogenesis of amyotrophic lateral sclerosis.
USP51 promotes non-small cell lung carcinoma cell stemness by deubiquitinating TWIST1.
Transcription Factor Nrf2 Modulates Lipopolysaccharide-Induced Injury in Bovine Endometrial Epithelial Cells.
Higher expression of pseudouridine synthase 7 promotes non-small cell lung cancer progression and suggests a poor prognosis.
Polyphyllin D punctures hypertrophic lysosomes to reverse drug resistance of hepatocellular carcinoma by targeting acid sphingomyelinase.
CircGNB1 facilitates the malignant phenotype of GSCs by regulating miR-515-5p/miR-582-3p-XPR1 axis.
KRT17 Promotes T-lymphocyte Infiltration Through the YTHDF2-CXCL10 Axis in Colorectal Cancer.
The promoting effect and mechanism of Nrf2 on cell metastasis in cervical cancer.
Sodium Propionate Relieves LPS-Induced Inflammation by Suppressing the NF-ĸB and MAPK Signaling Pathways in Rumen Epithelial Cells of Holstein Cows.
Exosomes promote hFOB1.19 proliferation and differentiation via LINC00520.
Oxygen-Sensing Protein Cysteamine Dioxygenase from Mandarin Fish Involved in the Arg/N-Degron Pathway and Siniperca chuatsi Rhabdovirus Infection.
Discovery of a Novel Bifunctional Steroid Analog, YXG-158, as an Androgen Receptor Degrader and CYP17A1 Inhibitor for the Treatment of Enzalutamide-Resistant Prostate Cancer.
Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice.
Disruption of neuronal RHEB signaling impairs oligodendrocyte differentiation and myelination through mTORC1-DLK1 axis.
Targeting CXCR1 alleviates hyperoxia-induced lung injury through promoting glutamine metabolism.
Neobavaisoflavone induces pyroptosis of liver cancer cells via Tom20 sensing the activated ROS signal.
The microbial metabolite Urolithin A reduces C. difficile toxin expression and repairs toxin-induced epithelial damage.
Mechanical force induces mitophagy-mediated anaerobic oxidation in periodontal ligament stem cells.
Induced neural stem cells suppressed neuroinflammation by inhibiting the microglial pyroptotic pathway in intracerebral hemorrhage rats.
Recombinant protein EBI3 attenuates Clonorchis sinensis-induced liver fibrosis by inhibiting hepatic stellate cell activation in mice.
Endoplasmic Reticulum Stress Mediated NLRP3 Inflammasome Activation and Pyroptosis in THP-1 Macrophages Infected with Bacillus Calmette-Guérin.
Quantitative Measurement of Secretory Protein Mistargeting by Proximity Labeling and Parallel Reaction Monitoring.
Single-cell transcriptome sequencing-based analysis: probing the mechanisms of glycoprotein NMB regulation of epithelial cells involved in silicosis.
Cold exposure protects against medial arterial calcification development via autophagy.
Protective effect of total flavonoids of Engelhardia roxburghiana Wall. leaves against radiation-induced intestinal injury in mice and its mechanism.
Mulberry leaves attenuate D-galactose-induced aging in vivo and in vitro.
Open source board based acoustofluidic transwells for reversible disruption of the blood-brain barrier for therapeutic delivery.
Recombinant humanized collagen type III with high antitumor activity inhibits breast cancer cells autophagy, proliferation, and migration through DDR1.
Transcriptome-Based Identification of the Muscle Tissue-Specific Expression Gene CKM and Its Regulation of Proliferation, Apoptosis and Differentiation in Chicken Primary Myoblasts.
VprBP/DCAF1 triggers melanomagenic gene silencing through histone H2A phosphorylation.
Glc7/PP1 dephosphorylates histone H3T11 to regulate autophagy and telomere silencing in response to nutrient availability.
Confirmation of the predictive function of cuproptosis-related gene FDX1 in clear cell renal carcinoma using qRT-PCR and western blotting.
TATA-box-binding protein promotes hepatocellular carcinoma metastasis through epithelial-mesenchymal transition.
Elevated FBXL18 promotes RPS15A ubiquitination and SMAD3 activation to drive HCC.
Tartary buckwheat flavonoids alleviates high-fat diet induced kidney fibrosis in mice by inhibiting MAPK and TGF-β1/Smad signaling pathway.
Enhanced autophagy reversed aflatoxin B1-induced decrease in lactate secretion of dairy goat Sertoli cells.
Microcystin‑leucine arginine promotes colorectal cancer cell proliferation by activating the PI3K/Akt/Wnt/β‑catenin pathway.
Ginsenoside Rg1 ameliorates chronic intermittent hypoxia-induced vascular endothelial dysfunction by suppressing the formation of mitochondrial reactive oxygen species through the calpain-1 pathway.
An in vivo and in vitro model on the protective effect of cilnidipine on contrast-induced nephropathy via regulation of apoptosis and CaMKⅡ/mPTP pathway.
Anti-Postmenopausal osteoporosis effects of Isopsoralen: A bioinformatics-integrated experimental study.
Silencing TRAIP suppresses cell proliferation and migration/invasion of triple negative breast cancer via RB-E2F signaling and EMT.
Nuclear factor Nrf2 promotes glycosidase OGG1 expression by activating the AKT pathway to enhance leukemia cell resistance to cytarabine.
Metabolomic and transcriptomic studies of improvements in myocardial infarction due to Pycr1 deletion.
Effect of transmembrane protein 100 on prostate cancer progression by regulating SCNN1D through the FAK/PI3K/AKT pathway.
CD166-specific CAR-T cells potently target colorectal cancer cells.
Spinal Cord Stimulation Attenuates Neural Remodeling, Inflammation, and Fibrosis After Myocardial Infarction.
Expression of group II metabotropic glutamate receptors in rat superior cervical ganglion.
Neuroprotective effect of histamine H3 receptor blockade on methamphetamine-induced cognitive impairment in mice.
ML390 inhibits enterovirus 71 replication by targeting de novo pyrimidine biosynthesis pathway.
Inhibition of deubiquitinase USP28 attenuates cyst growth in autosomal dominant polycystic kidney disease.
Protective Mechanism of Ethyl Gallate against Intestinal Ischemia-Reperfusion Injury in Mice by in Vivo and in Vitro Studies Based on Transcriptomics.
Translational control of murine adiponectin expression by an upstream open reading frame element.
Critical role of caveolin-1 in intestinal ischemia reperfusion by inhibiting protein kinase C βII.
Fluvoxamine alleviates bleomycin-induced lung fibrosis via regulating the cGAS-STING pathway.
Pine pollen extract alleviates ethanol-induced oxidative stress and apoptosis in HepG2 cells via MAPK signaling.
Polysaccharide-rich fractions from Enteromorpha prolifera improve hepatic steatosis and gut barrier integrity in high-fat diet-induced obese mice linking to modulation of gut microbiota.
Knockdown of Brg1 reduced mucus secretion in HDM stimulated airway inflammation.
Multiomics analyses and machine learning of nuclear receptor coactivator 6 reveal its essential role in hepatocellular carcinoma.
PLD2 deletion alleviates disruption of tight junctions in sepsis-induced ALI by regulating PA/STAT3 phosphorylation pathway.
Huc-MSCs-derived exosomes attenuate neuropathic pain by inhibiting activation of the TLR2/MyD88/NF-κB signaling pathway in the spinal microglia by targeting Rsad2.
Methyl gallate prevents oxidative stress induced apoptosis and ECM degradation in chondrocytes via restoring Sirt3 mediated autophagy and ameliorates osteoarthritis progression.
Chinese herbal medicine alleviates the pathogenesis of polycystic ovary syndrome by improving oxidative stress and glucose metabolism via mitochondrial Sirtuin 3 signaling.
Yishen-Qingli-Huoxue formula attenuates renal fibrosis by inhibiting indoxyl sulfate via AhR/snai1 signaling.
Involvement of Galectin-3 in neurocognitive impairment in obstructive sleep apnea via regulating inflammation and oxidative stress through NLRP3.
Disruption of COMMD1 accelerates diabetic atherosclerosis by promoting glycolysis.
Heat enhances the inhibitory effect of lipopolysaccharide on duck granulosa cell proliferation and steroid biosynthesis in vitro.
Caveolae-associated protein 3 promotes adipogenic differentiation of porcine preadipocytes by promoting extracellular signal-regulated kinase phosphorylation.
Cancer susceptibility 18 positively regulates NUAK Family Kinase 1 expression to promote migration and invasion via sponging of miR-5586-5p in cervical cancer cells.
Human Umbilical Cord Mesenchymal Stem Cells Improve the Status of Hypoxic/Ischemic Cerebral Palsy Rats by Downregulating NogoA/NgR/Rho Pathway.
Pomegranate Peel Extract Sensitizes Hepatocellular Carcinoma Cells to Ionizing Radiation, Induces Apoptosis and Inhibits MAPK, JAK/STAT3, β-Catenin/NOTCH, and SOCS3 Signaling.
Dehydrocorydaline alleviates sleep deprivation-induced persistent postoperative pain in adolescent mice through inhibiting microglial P2Y(12) receptor expression in the spinal cord.
YAP and β-catenin cooperate to drive H. pylori-induced gastric tumorigenesis.
Cryptotanshinone modulates proliferation, apoptosis, and fibrosis through inhibiting AR and EGFR/STAT3 axis to ameliorate benign prostatic hyperplasia progression.
Ring domains are essential for GATOR2-dependent mTORC1 activation.
NAMPT inhibition reduces macrophage inflammation through the NAD+/PARP1 pathway to attenuate liver ischemia-reperfusion injury.
Multimodal rehabilitation promotes axonal sprouting and functional recovery in a murine model of spinal cord injury (SCI).
NLRP3 activation in microglia contributes to learning and memory impairment induced by chronic lead exposure in mice.
E2F1 combined with LINC01004 super-enhancer to promote hepatocellular carcinoma cell proliferation and metastasis.
GPR109A controls neutrophil extracellular traps formation and improve early sepsis by regulating ROS/PAD4/Cit-H3 signal axis.
S-Doped carbonized polymer dots inhibit early myocardial fibrosis by regulating mitochondrial function.
Inhibition of Checkpoint Kinase 1 (CHK1) Upregulates Interferon Regulatory Factor 1 (IRF1) to Promote Apoptosis and Activate Anti-Tumor Immunity via MICA in Hepatocellular Carcinoma (HCC).
Dietary alpha-ketoglutarate enhances intestinal immunity by Th17/Treg immune response in piglets after lipopolysaccharide challenge.
Lipopolysaccharide promotes apoptosis and oxidative injury of porcine small intestinal epithelial cells by down-regulating the expression of glutamine transporter ASCT2.
Activation of autophagy inhibits the activation of NLRP3 inflammasome and alleviates sevoflurane-induced cognitive dysfunction in elderly rats.
ANXA10 is a prognostic biomarker and suppressor of hepatocellular carcinoma: a bioinformatics analysis and experimental validation.
DHAV 3CD targets IRF7 and RIG-I proteins to block the type I interferon upstream signaling pathway.
Ginsenoside Compound K Ameliorates Osteoarthritis by Inhibiting the Chondrocyte Endoplasmic Reticulum Stress-Mediated IRE1α-TXNIP-NLRP3 Axis and Pyroptosis.
Dendrobine Alleviates Cellular Senescence and Osteoarthritis via the ROS/NF-κB Axis.
The m(6)A Reader YTHDF1 Promotes Lung Carcinoma Progression via Regulating Ferritin Mediate Ferroptosis in an m(6)A-Dependent Manner.
Proteome-Wide Analysis Reveals TFEB Targets for Establishment of a Prognostic Signature to Predict Clinical Outcomes of Colorectal Cancer.
Silencing SOX11 Alleviates Allergic Rhinitis by Inhibiting Epithelial-Derived Cytokines.
NFYAv1 is a Tumor-Promoting Transcript Associated with Poor Prognosis of Hepatocellular Carcinoma.
SLC17A9-PTHLH-EMT axis promotes proliferation and invasion of clear renal cell carcinoma.
Synthesis of Novel Pentacyclic Triterpenoid Derivatives that Induce Apoptosis in Cancer Cells through a ROS-dependent, Mitochondrial-Mediated Pathway.
Increased endogenous PKG I activity attenuates EGF-induced proliferation and migration of epithelial ovarian cancer via the MAPK/ERK pathway.
Construction and Rescue of a DNA-Launched DENV2 Infectious Clone.
Inhibition of Klf10 Attenuates Oxidative Stress-Induced Senescence of Chondrocytes via Modulating Mitophagy.
Robo4 inhibits gamma radiation-induced permeability of a murine microvascular endothelial cell by regulating the junctions.
Analysis of Promoter Methylation of the Bovine FOXO1 Gene and Its Effect on Proliferation and Differentiation of Myoblasts.
N-acetyl-L-cysteine alleviates FUNDC1-mediated mitophagy by regulating mitochondrial dynamics in type 1 diabetic nephropathy canine.
Molecular mechanism of the miR-7/BCL2L1/P53 signaling axis regulating the progression of hepatocellular carcinoma.
Exogenous H(2)S Attenuates Hypertension by Regulating Renin Exocytosis under Hyperglycaemic and Hyperlipidaemic Conditions.
The Effect of an Essential Oil Blend on Growth Performance, Intestinal Health, and Microbiota in Early-Weaned Piglets.
Glioma-derived LRIG3 interacts with NETO2 in tumor-associated macrophages to modulate microenvironment and suppress tumor growth.
Oncolytic Hairpin DNA Pair: Selective Cytotoxic Inducer through MicroRNA-Triggered DNA Self-Assembly.
Pulsatilla decoction improves DSS-induced colitis via modulation of fecal-bacteria-related short-chain fatty acids and intestinal barrier integrity.
The main e-cigarette component vegetable glycerin enhances neutrophil migration and fibrosis in endotoxin-induced lung injury via p38 MAPK activation.
CMTM6 overexpression confers trastuzumab resistance in HER2-positive breast cancer.
Organic extracts in PM2.5 are the major triggers to induce ferroptosis in SH-SY5Y cells.
FSH-inhibited autophagy protects against oxidative stress in goat Sertoli cells through p62-Nrf2 pathway.
Proximal tubular Bmal1 protects against chronic kidney injury and renal fibrosis by maintaining of cellular metabolic homeostasis.
Daucosterol Alleviates Alcohol-Induced Hepatic Injury and Inflammation through P38/NF-κB/NLRP3 Inflammasome Pathway.
An interventional study of baicalin on neuronal pentraxin-1, neuronal pentraxin-2, and C-reactive protein in Alzheimer's disease rat model.
Long noncoding RNA SNHG1 alleviates high glucose-induced vascular smooth muscle cells calcification/senescence by post-transcriptionally regulating Bhlhe40 and autophagy via Atg10.
GOLM1 facilitates human colorectal cancer progression and metastasis via activating the AKT/GSK3β/EMT axis.
Elevated PGT promotes proliferation and inhibits cell apoptosis in preeclampsia by Erk signaling pathway.
The antiviral activity of tripartite motif protein 38 in hepatitis B virus replication and gene expression and its association with treatment responses during PEG-IFN-α antiviral therapy.
Huntingtin-associated protein 1 is a potential tumor suppressor for gastric cancer.
Dual Antioxidant DH-217 Mitigated Cerebral Ischemia-Reperfusion Injury by Targeting IKKβ/Nrf2/HO-1 Signal Axis.
MiR-29c Inhibits TNF-α-Induced ROS Production and Apoptosis in Mouse Hippocampal HT22 Cell Line.
cPKCγ Inhibits Caspase-9-Initiated Neuronal Apoptosis in an Ischemia Reperfusion Model In Vitro Through p38 MAPK-p90RSK-Bad Pathway.
PCSK9 Promotes Endothelial Dysfunction During Sepsis Via the TLR4/MyD88/NF-κB and NLRP3 Pathways.
Synergistic anticancer effect of flavonoids from Sophora alopecuroides with Sorafenib against hepatocellular carcinoma.
VEZF1, destabilized by STUB1, affects cellular growth and metastasis of hepatocellular carcinoma by transcriptionally regulating PAQR4.
S100A1 expression is increased in spinal cord injury and promotes inflammation, oxidative stress and apoptosis of PC12 cells induced by LPS via ERK signaling.
Turnip crinkle virus-encoded suppressor of RNA silencing interacts with Arabidopsis SGS3 to enhance virus infection.
Cyasterone inhibits IL-1β-mediated apoptosis and inflammation via the NF-κB and MAPK signaling pathways in rat chondrocytes and ameliorates osteoarthritisin vivo.
Oleoylethanolamide alleviates hyperlipidaemia-mediated vascular calcification via attenuating mitochondrial DNA stress triggered autophagy-dependent ferroptosis by activating PPARα.
Pharmacological vitamin C inhibits mTOR signaling and tumor growth by degrading Rictor and inducing HMOX1 expression.
Neural stem cell-derived exosome as a nano-sized carrier for BDNF delivery to a rat model of ischemic stroke.
Platelet-derived extracellular vesicles ameliorate intervertebral disc degeneration by alleviating mitochondrial dysfunction.
Plasma microRNA expression profiles associated with zinc exposure and type 2 diabetes mellitus: Exploring potential role of miR-144-3p in zinc-induced insulin resistance.
CXCL11 negatively regulated by MED19 favours antitumour immune infiltration in breast cancer.
Exosomes Derived from AT2R-Overexpressing BMSC Prevent Restenosis After Carotid Artery Injury by Attenuating the Injury-Induced Neointimal Hyperplasia.
Exercise induced meteorin-like protects chondrocytes against inflammation and pyroptosis in osteoarthritis by inhibiting PI3K/Akt/NF-κB and NLRP3/caspase-1/GSDMD signaling.
Porous composite hydrogels with improved MSC survival for robust epithelial sealing around implants and M2 macrophage polarization.
Effects of lactate on metabolism and differentiation of CD4(+)T cells.
Heliangin acts as a covalent ligand of RPS2 that disrupts pre-rRNA metabolic processes in NPM1-mutated acute myeloid leukemia.
PKM2-mediated neuronal hyperglycolysis enhances the risk of Parkinson's disease in diabetic rats.
Low dose TGF-β1 can improve vohwinkel syndrome by promoting the proliferation of keratinocytes.
Tumor-derived endomucin promotes colorectal cancer proliferation and metastasis.
α-Cyperone protects dopaminergic neurons and inhibits neuroinflammation in LPS-induced Parkinson's disease rat model via activating Nrf2/HO-1 and suppressing NF-κB signaling pathway.
Mesenchymal stem cell-derived extracellular vesicles carrying miR-99b-3p restrain microglial activation and neuropathic pain by stimulating autophagy.
Stevioside targets the NF-κB and MAPK pathways for inhibiting inflammation and apoptosis of chondrocytes and ameliorates osteoarthritis in vivo.
Ferroptosis is involved in PM2.5-induced acute nasal epithelial injury via AMPK-mediated autophagy.
IL-33/ST2 mediating systemic inflammation and neuroinflammation through NF-kB participated in the neurocognitive impairment in obstructive sleep apnea.
Citrus peel ameliorates mucus barrier damage in HFD-fed mice.
Preventive effect of salmon sperm DNA on acute carbon tetrachloride-induced liver injury in mice through Nrf2/ARE and mitochondrial apoptosis pathway.
Folate inhibits lipid deposition via the autophagy pathway in chicken hepatocytes.
Research Note: Duck plague virus pUL48 is a late protein that plays an important role in viral replication.
Tryptophan Metabolism Acts as a New Anti-Ferroptotic Pathway to Mediate Tumor Growth.
Cholesterol-Lowering Activity of Vitisin A Is Mediated by Inhibiting Cholesterol Biosynthesis and Enhancing LDL Uptake in HepG2 Cells.
Blockage of glycolysis by targeting PFKFB3 suppresses the development of infantile hemangioma.
Application of neural network-based image analysis to detect sister chromatid cohesion defects.
Ginsenoside Rh2 inhibits CBP/p300-mediated FOXO3a acetylation and epilepsy-induced oxidative damage via the FOXO3a-KEAP1-NRF2 pathway.
Novel ELAC2 Mutations in Individuals Presenting with Variably Severe Neurological Disease in the Presence or Absence of Cardiomyopathy.
Depletion of SOD2 enhances nasopharyngeal carcinoma cell radiosensitivity via ferroptosis induction modulated by DHODH inhibition.
Glycolysis-related lncRNA TMEM105 upregulates LDHA to facilitate breast cancer liver metastasis via sponging miR-1208.
The Protective Role of Scorias spongiosa Polysaccharide-Based Microcapsules on Intestinal Barrier Integrity in DSS-Induced Colitis in Mice.
African Swine Fever Virus L83L Negatively Regulates the cGAS-STING-Mediated IFN-I Pathway by Recruiting Tollip To Promote STING Autophagic Degradation.
DDX3X Is Hijacked by Snakehead Vesiculovirus Phosphoprotein To Facilitate Virus Replication via Stabilization of the Phosphoprotein.
Transcytosable Peptide-Paclitaxel Prodrug Nanoparticle for Targeted Treatment of Triple-Negative Breast Cancer.
CENPF promotes the proliferation of renal cell carcinoma in vitro.
Protective effects of pentoxifylline against chlorine-induced acute lung injury in rats.
ADSC-derived exosomes attenuate myocardial infarction injury by promoting miR-205-mediated cardiac angiogenesis.
Acupuncture exerts preventive effects in rats of chronic unpredictable mild stress: The involvement of inflammation in amygdala and brain-spleen axis.
SERPINF1 Mediates Tumor Progression and Stemness in Glioma.
The total polyphenolic glycoside extract of Lamiophlomis rotata ameliorates hepatic fibrosis through apoptosis by TGF-β/Smad signaling pathway.
1α,25(OH)(2)D(3) Promotes the Autophagy of Porcine Ovarian Granulosa Cells as a Protective Mechanism against ROS through the BNIP3/PINK1 Pathway.
Anti-tumor effect of infant-derived Enterococcus via the inhibition of proliferation and inflammation as well as the promotion of apoptosis.
Anti-glycation and anti-inflammatory activities of anthocyanins from purple vegetables.
Glioblastoma upregulates SUMOylation of hnRNP A2/B1 to eliminate the tumor suppressor miR-204-3p, accelerating angiogenesis under hypoxia.
A novel Hoxd13 mutation causes synpolydactyly and promotes osteoclast differentiation by regulating pSmad5/p65/c-Fos/Rank axis.
Alpha-kinase1 promotes tubular injury and interstitial inflammation in diabetic nephropathy by canonical pyroptosis pathway.
Exendin-4 alleviates myocardial ischemia reperfusion injury by enhancing autophagy through promoting nuclear translocation of TFEB.
Prognosis, immune microenvironment, and personalized treatment prediction in Rho GTPase-activating protein 4-mutant cervical cancer: Computer strategies for precision oncology.
Design, synthesis and anti-AD effects of dual inhibitor targeting glutaminyl cyclase/GSK-3β.
Caspase-11 contributes to pain hypersensitivity in the later phase of CFA-induced pain of mice.
Neuroprotective Effects of Sodium Butyrate by Restoring Gut Microbiota and Inhibiting TLR4 Signaling in Mice with MPTP-Induced Parkinson's Disease.
Rho A/ROCK1 signaling-mediated metabolic reprogramming of valvular interstitial cells toward Warburg effect accelerates aortic valve calcification via AMPK/RUNX2 axis.
Degradation of Perineuronal Nets in the Cerebellar Interpositus Nucleus Ameliorated Social Deficits in Shank3-deficient Mice.
UBE2E2 enhances Snail-mediated epithelial-mesenchymal transition and Nrf2-mediated antioxidant activity in ovarian cancer.
Silica nanoparticles suppressed the spermatogenesis via downregulation of miR-450b-3p by targeting Layilin in spermatocyte of mouse.
The Activation of Reticulophagy by ER Stress through the ATF4-MAP1LC3A-CCPG1 Pathway in Ovarian Granulosa Cells Is Linked to Apoptosis and Necroptosis.
Hypoxia Inhibits Cell Cycle Progression and Cell Proliferation in Brain Microvascular Endothelial Cells via the miR-212-3p/MCM2 Axis.
2-Undecanone alleviates asthma by inhibiting NF-κB pathway.
Estrogen inhibits the differentiation of fibroblasts induced by high stiffness matrix by enhancing DNMT1 expression.
Discovery of novel pyrido[3,2-d]pyrimidine derivatives as selective and potent PI3Kδ inhibitors.
The SIRT3 activator ganoderic acid D regulates airway mucin MUC5AC expression via the NRF2/GPX4 pathway.
AKAP12 inhibits esophageal squamous carcinoma cell proliferation, migration, and cell cycle via the PI3K/AKT signaling pathway.
Vitamin D Receptor Activation Attenuates Olanzapine-Induced Dyslipidemia in Mice Through Alleviating Hepatic Endoplasmic Reticulum Stress.
Dimethyl fumarate ameliorates erectile dysfunction in bilateral cavernous nerve injury rats by inhibiting oxidative stress and NLRP3 inflammasome-mediated pyroptosis of nerve via activation of Nrf2/HO-1 signaling pathway.
Schisandrin B promotes senescence of activated hepatic stellate cell via NCOA4-mediated ferritinophagy.
(-)-Epigallocatechin-3-gallate promotes intestinal epithelial proliferation and barrier function after ischemia/reperfusion injury via activation of Nurr1.
Glucocorticoid receptors involved in ginsenoside compound K ameliorate adjuvant arthritis by inhibiting the glycolysis of fibroblast-like synoviocytes via the NF-κB/HIF-1α pathway.
Mechanisms of dihydromyricetin against hepatocellular carcinoma elucidated by network pharmacology combined with experimental validation.
Intracerebral Hemorrhage-Induced Brain Injury: the Role of Lysosomal-Associated Transmembrane Protein 5.
USP10 promotes intrahepatic cholangiocarcinoma cell survival and stemness via SNAI1 deubiquitination.
Compound Dihuang Granule Changes Gut Microbiota of MPTP-Induced Parkinson's Disease Mice via Inhibiting TLR4/NF-κB Signaling.
Apelin-13 alleviates contrast-induced acute kidney injury by inhibiting endoplasmic reticulum stress.
Targeting proteasomal deubiquitinases USP14 and UCHL5 with b-AP15 reduces 5-fluorouracil resistance in colorectal cancer cells.
Protein Disulfide Isomerase A2 Is Correlated with Immune Infiltrates and Is a Novel Prognostic Biomarker in Glioma Patients.
Rhein protects retinal Müller cells from high glucose-induced injury via activating the AMPK/Sirt1/PGC-1α pathway.
Peripheral BDNF Regulates Somatosensory-Sympathetic Coupling in Brachial Plexus Avulsion-Induced Neuropathic Pain.
Induction of heme oxygenase-1 antagonizes PM2.5-induced pulmonary VEGFA expression through regulating HIF-1α.
Artificially reprogrammed stem cells deliver transcytosable nanocomplexes for improved spinal cord repair.
Curcumin Alleviates Hepatic Ischemia-Reperfusion Injury by Inhibiting Neutrophil Extracellular Traps Formation.
miRNA-381 regulates renal cancer stem cell properties and sunitinib resistance via targeting SOX4.
Effects of heat shock protein 90 on complement activation in myocardial ischemia/reperfusion injury after pioglitazone preconditioning.
The nanoprodrug of polytemozolomide combines with MGMT siRNA to enhance the effect of temozolomide in glioma.
HIF-1α promotes astrocytic production of macrophage migration inhibitory factor following spinal cord injury.
Vitamin D3 alleviates lung fibrosis of type 2 diabetic rats via SIRT3 mediated suppression of pyroptosis.
BNIP3 overexpression may promote myeloma cell apoptosis by enhancing sensitivity to bortezomib via the p38 MAPK pathway.
Brusatol enhances MEF2A expression to inhibit RCC progression through the Wnt signalling pathway in renal cell carcinoma.
Dihydroartemisinin inhibits liver cancer cell migration and invasion by reducing ATP synthase production through CaMKK2/NCLX.
Hsa_circ_0003596 enhances the development of cell renal clear cell carcinoma through the miR-502-5p/IGF1/PI3K/AKT axis.
20-Deoxyingenol alleviates intervertebral disc degeneration by activating TFEB in nucleus pulposus cells.
The Combination of Methioninase and Ethionine Exploits Methionine Addiction to Selectively Eradicate Osteosarcoma Cells and Not Normal Cells and Synergistically Down-regulates the Expression of C-MYC.
Identification of antioxidant peptides targeting Keap1-Nrf2-ARE pathway from in vitro digestion of pork sausage with partial substitution of NaCl by KCl.
Enzyme-responsive nanospheres target senescent cells for diabetic wound healing by employing chemodynamic therapy.
Chemical constituents from Eupatorium fortunei and their anti-inflammatory evaluation by in silico and experimental approaches.
Bioinformatics analysis identifies the protective targets of omentin in mice with focal cerebral ischemia injury.
Fibroblast growth factor 21 protects the liver from apoptosis in a type 1 diabetes mouse model via regulating L-lactate homeostasis.
The JAK/STAT/NF-κB signaling pathway can be regulated by rosemary essential oil, thereby providing a potential treatment for DNCB-induced in mice.
Antinociceptive and neuroprotective effect of echinacoside on peripheral neuropathic pain in mice through inhibiting P2X7R/FKN/CX3CR1 pathway.
Allantoin Derived From Dioscorea opposita Thunb Ameliorates Cyclophosphamide-Induced Premature Ovarian Failure in Female Rats by Attenuating Apoptosis, Autophagy and Pyroptosis.
Constitutive photomorphogenic protein 1 ubiquitinates interleukin-1 receptor accessory protein in human liver cancer.
Discovery of selective and potent USP22 inhibitors via structure-based virtual screening and bioassays exerting anti-tumor activity.
Flanking N- and C-terminal domains of PrsA in Streptococcus suis type 2 are crucial for inducing cell death independent of TLR2 recognition.
Activation of cGAS-STING signaling pathway promotes liver fibrosis and hepatic sinusoidal microthrombosis.
Pemetrexed ameliorates Con A-induced hepatic injury by restricting M1 macrophage activation.
Zinc regulates a specific subpopulation of VEGFA + microglia to improve the hypoxic microenvironment for functional recovery after spinal cord injury.
In vitro validation: GLY alleviates UV-induced corneal epithelial damage through the HMGB1-TLR/MyD88-NF-κB signaling pathway.
Isovitexin alleviates hepatic fibrosis by regulating miR-21-mediated PI3K/Akt signaling and glutathione metabolic pathway: based on transcriptomics and metabolomics.
The effects of astragaloside IV on gut microbiota and serum metabolism in a mice model of intracerebral hemorrhage.
Phosphorylated Hsp27 promotes adriamycin resistance in breast cancer cells through regulating dual phosphorylation of c-Myc.
Activation of AHR by ITE improves cardiac remodelling and function in rats after myocardial infarction.
LincRNA01703 Facilitates CD81(+) Exosome Secretion to Inhibit Lung Adenocarcinoma Metastasis via the Rab27a/SYTL1/CD81 Complex.
Styrax (Liquidambar orientalis Mill.) promotes mitochondrial function and reduces cardiac damage following myocardial ischemic injury: the role of the AMPK-PGC1α signaling pathway.
Molecular Targets and Mechanisms of Casein-Derived Tripeptides Ile-Pro-Pro and Val-Pro-Pro on Hepatic Glucose Metabolism.
Phenolic Constituents from Black Quinoa Alleviate Insulin Resistance in HepG2 Cells via Regulating IRS1/PI3K/Akt/GLUTs Signaling Pathways.
Recombinant human erythropoietin protects against immature brain damage induced by hypoxic/ischemia insult.
RUNX1 knockdown induced apoptosis and impaired EMT in high-grade serous ovarian cancer cells.
Circular RNA circATP9A promotes non-small cell lung cancer progression by interacting with HuR and by promoting extracellular vesicles-mediated macrophage M2 polarization.
Exploring the pharmacological mechanisms and key active ingredients of total flavonoids from Lamiophlomis rotata (Benth.) Kudo against rheumatoid arthritis based on multi-technology integrated network pharmacology.
Modification of osimertinib to discover new potent EGFR(C797S)-TK inhibitors.
Discovery of highly potent and selective KRAS(G12C) degraders by VHL-recruiting PROTACs for the treatment of tumors with KRAS(G12C)-Mutation.
Ethanol extract of Paridis rhizoma attenuates carrageenan-induced paw swelling in rats by inhibiting the production of inflammatory factors.
Canagliflozin ameliorates hypobaric hypoxia-induced pulmonary arterial hypertension by inhibiting pulmonary arterial smooth muscle cell proliferation.
A20 ameliorates Aspergillus fumigatus keratitis by promoting autophagy and inhibiting NF-κB signaling.
Mesenchymal stem cell conditioned medium alleviates acute lung injury through KGF-mediated regulation of epithelial sodium channels.
Ramelteon attenuates renal ischemia and reperfusion injury through reducing mitochondrial fission and fusion and inflammation.
MicroRNA miR-212-5p Regulates the MEK/ERK Signaling Pathway by Targeting A-Raf proto-oncogene serine/threonine-protein kinase (ARAF) to Regulate Cowshed PM(2.5)-Induced NR8383 Apoptosis.
Exosome-Related FTCD Facilitates M1 Macrophage Polarization and Impacts the Prognosis of Hepatocellular Carcinoma.
Isoliquiritigenin Inhibits the Growth of Colorectal Cancer Cells through the ESR2/PI3K/AKT Signalling Pathway.
Fucoxanthin diminishes oxidative stress damage in human placenta-derived mesenchymal stem cells through the PI3K/Akt/Nrf-2 pathway.
LINC00921 reduces lung cancer radiosensitivity by destabilizing NUDT21 and driving aberrant MED23 alternative polyadenylation.
Exploration of the Pharmacological Mechanism of Vitexicarpin against Triple-Negative Breast Cancer in Network Pharmacology.
Y-box protein-1 modulates circSPECC1 to promote glioma tumorigenesis via miR-615-5p/HIP1/AKT axis.
Elevated FBXL6 activates both wild-type KRAS and mutant KRAS(G12D) and drives HCC tumorigenesis via the ERK/mTOR/PRELID2/ROS axis in mice.
ER Stress-Perturbed Intracellular Protein O-GlcNAcylation Aggravates Podocyte Injury in Diabetes Nephropathy.
Hypoxia promotes the growth and metastasis of ovarian cancer cells by suppressing ferroptosis via upregulating SLC2A12.
Identification of the role of MCM6 in bladder cancer prognosis, immunotherapy response, and in vitro experimental investigation using multi-omics analysis.
Depletion of gut microbiota facilitates fibroblast growth factor 21-mediated protection against acute pancreatitis in diabetic mice.
Transcriptome-wide N(6)-methyladenosine methylation profile of atherosclerosis in mice.
Anti-VEGFR2 F(ab')(2) drug conjugate promotes renal accumulation and glomerular repair in diabetic nephropathy.
Cirsiliol induces autophagy and mitochondrial apoptosis through the AKT/FOXO1 axis and influences methotrexate resistance in osteosarcoma.
Silk Fibroin-Modified Liposome/Gene Editing System Knocks out the PLK1 Gene to Suppress the Growth of Lung Cancer Cells.
Therapeutic protein PAK restrains the progression of triple negative breast cancer through degrading SREBP-1 mRNA.
Decreased intracellular chloride enhances cell migration and invasion via activation of the ERK1/2 signaling pathway in DU145 human prostate carcinoma cells.
Corilagin attenuates intestinal ischemia/reperfusion injury in mice by inhibiting ferritinophagy-mediated ferroptosis through disrupting NCOA4-ferritin interaction.
A comprehensive multiomics approach reveals that high levels of sphingolipids in cardiac cachexia adipose tissue are associated with inflammatory and fibrotic changes.
An HBV susceptibility variant of KNG1 modulates the therapeutic effects of interferons α and λ1 in HBV infection by promoting MAVS lysosomal degradation.
Dapagliflozin impedes endothelial cell senescence by activating the SIRT1 signaling pathway in type 2 diabetes.
XBP1s gene of endoplasmic reticulum stress enhances proliferation and osteogenesis of human periodontal ligament cells.
Salt-inducible kinase inhibition promotes the adipocyte thermogenic program and adipose tissue browning.
α-Lactalbumin Peptide Asp-Gln-Trp Ameliorates Hepatic Steatosis and Oxidative Stress in Free Fatty Acids-Treated HepG2 Cells and High-Fat Diet-Induced NAFLD Mice by Activating the PPARα Pathway.
Title: Bioinformatic Identification of Genes Involved in Diabetic Nephropathy Fibrosis and their Clinical Relevance.
Sirt1 Overexpression Inhibits Fibrous Scar Formation and Improves Functional Recovery After Cerebral Ischemic Injury Through the Deacetylation of 14-3-3ζ.
DNA damage-inducible transcript 3 deficiency promotes bone resorption in murine periodontitis models.
Knockdown of CENPN Inhibits Glucose Metabolism and Induces G1 Arrest in Esophageal Cancer Cells by Regulating PI3K/AKT Signaling Pathway.
Natural killer cells strengthen antitumor activity of cisplatin by immunomodulation and ameliorate cisplatin-induced side effects.
Repetitive transcranial magnetic stimulation alleviates glial activation through suppressing HMGB1/TLR4 pathway in a rat model of Parkinson's disease.
Significance of UGT1A6, UGT1A9, and UGT2B7 genetic variants and their mRNA expression in the clinical outcome of renal cell carcinoma.
USP33 enhances cell survival and stemness by deubiquitinating CTNNB1 in BXPC-3 and SW1990 cells.
Hydrogen sulfide alleviates beryllium sulfate-induced ferroptosis and ferritinophagy in 16HBE cells.
An early-onset SLE patient with a novel paternal inherited BACH2 mutation.
Catalpol Prevents Glomerular Angiogenesis Induced by Advanced Glycation End Products via Inhibiting Galectin-3.
Naringin protects against inflammation and apoptosis induced by intestinal ischemia-reperfusion injury through deactivation of cGAS-STING signaling pathway.
Klotho gene might antagonize ischemic injury in stroke rats by reducing the expression of AQP4 via P38MAPK pathway.
Diosmetin alleviates acute lung injury caused by lipopolysaccharide by targeting barrier function.
Extracellular vesicles released by glioma cells are decorated by Annexin A2 allowing for cellular uptake via heparan sulfate.
The role of ROS/p38 MAPK/NLRP3 inflammasome cascade in arsenic-induced depression-/anxiety-like behaviors of mice.
Ginsenoside compound K alleviates osteoarthritis by inhibiting NLRP3‑mediated pyroptosis.
SOX9/NFIA promotes human ovarian cancer metastasis through the Wnt/β-catenin signaling pathway.
SlMYB99-mediated auxin and abscisic acid antagonistically regulate ascorbic acids biosynthesis in tomato.
Rapamycin inhibits corneal inflammatory response and neovascularization in a mouse model of corneal alkali burn.
Induction of SGK1 via glucocorticoid-influenced clinical outcome of triple-negative breast cancer patients.
Exosomes from Human Umbilical Cord Mesenchymal Stem Cells Facilitates Injured Endometrial Restoring in Early Repair Period through miR-202-3p Mediating Formation of ECM.
M2 Macrophage Membrane-Mediated Biomimetic-Nanoparticle Carrying COX-siRNA Targeted Delivery for Prevention of Tendon Adhesions by Inhibiting Inflammation.
NRF2 activation suppresses motor neuron ferroptosis induced by the SOD1(G93A) mutation and exerts neuroprotection in amyotrophic lateral sclerosis.
Macrophage migration inhibitory factor facilitates astrocytic production of the CCL2 chemokine following spinal cord injury.
Environmentally relevant exposure to cypermethrin aggravates diet-induced diabetic symptoms in mice: The interaction between environmental chemicals and diet.
Sodium houttuyfonate plays a protective role in the asthmatic airway by alleviating the NLRP3-related pyroptosis and Th1/Th2 immune imbalance.
Long non-coding RNA ENST00000503625 is a potential prognostic biomarker and metastasis suppressor gene in prostate cancer.
Genetic and pharmacological inhibition of METTL3 alleviates renal fibrosis by reducing EVL m6A modification through an IGF2BP2-dependent mechanism.
Hypoxia induces the production of epithelial-derived cytokines in eosinophilic chronic rhinosinusitis with nasal polyps.
Neutrophils regulate tumor angiogenesis in oral squamous cell carcinoma and the role of Chemerin.
ABCG2 plays a central role in the dysregulation of 25-hydrovitamin D in Crohn's disease.
Ketogenic diet alleviates renal interstitial fibrosis in UUO mice by regulating macrophage proliferation.
Nervonic acid improves liver inflammation in a mouse model of Parkinson's disease by inhibiting proinflammatory signaling pathways and regulating metabolic pathways.
O-GlcNAcylation enhances Reticulon 2 protein stability and its promotive effects on gastric cancer progression.
NQO1 alleviates renal fibrosis by inhibiting the TLR4/NF-κB and TGF-β/Smad signaling pathways in diabetic nephropathy.
A Recombinant Parathyroid Hormone-Related Peptide Locally Applied in Osteoporotic Bone Defect.
Curcumin enhances elvitegravir concentration and alleviates oxidative stress and inflammatory response.
Diosgenin attenuates nonalcoholic hepatic steatosis through the hepatic FXR-SHP-SREBP1C/PPARα/CD36 pathway.
The effects of acupuncture on depression by regulating BDNF-related balance via lateral habenular nucleus BDNF/TrkB/CREB signaling pathway in rats.
Cordycepin inhibits ERK pathway to suppress FGF9-induced tumorigenesis with MA-10 mouse Leydig tumor cells.
SUMOylation of SMAD4 by PIAS1 in Conjunction with Vimentin Upregulation Promotes Migration Potential in Non-Small Cell Lung Cancer.
The cellular uptake of Cordyceps sinensis exopolysaccharide‑selenium nanoparticles and their induced apoptosis of HepG2 cells via mitochondria- and death receptor-mediated pathways.
Microglial NLRP3 inflammasome activation mediates diabetes-induced depression-like behavior via triggering neuroinflammation.
Antioxidant Behavioural Phenotype in the Immp2l Gene Knock-Out Mouse.
The circadian rhythm regulates branched-chain amino acids metabolism in fast muscle of Chinese perch (Siniperca chuatsi) during short-term fasting by Clock-KLF15-Bcat2 pathway.
Identification of Ecdysteroid Sinapate Esters with COX-2 Inhibitory Effects from Fibraurea recisa Using Molecular Networking and MS2LDA.
Berberine-loaded MSC-derived sEVs encapsulated in injectable GelMA hydrogel for spinal cord injury repair.
CXCL8 Promotes Endothelial-to-Mesenchymal Transition of Endothelial Cells and Protects Cells from Erastin-Induced Ferroptosis via CXCR2-Mediated Activation of the NF-κB Signaling Pathway.
α-Synuclein-carrying astrocytic extracellular vesicles in Parkinson pathogenesis and diagnosis.
SYNJ1 rescues motor functions in hereditary and sporadic Parkinson's disease mice by upregulating TSP-1 expression.
LncRNA SOCS2-AS1 promotes the progression of papillary thyroid cancer by destabilizing p53 protein.
WITHDRAWN: Expression of Tmem41b and MMP13 associated with poor outcome in osteosarcomas.
Hypermethylation of RNF125 promotes autophagy-induced oxidative stress in asthma by increasing HMGB1 stability.
GM-CSF receptor/SYK/JNK/FOXO1/CD11c signaling promotes atherosclerosis.
Transcriptomics Reveals Molecular Features of the Bilateral Pelvic Nerve Injury Rat Model of Detrusor Underactivity.
Lactate dehydrogenase D serves as a novel biomarker for prognosis and immune infiltration in lung adenocarcinoma.
Immunogenic cell death-based prognostic model for predicting the response to immunotherapy and common therapy in lung adenocarcinoma.
Effects of proanthocyanidins and dialdehyde chitosan on the proliferation and differentiation of bovine myoblast for cultured meat production.
TNFSF14/LIGHT promotes cardiac fibrosis and atrial fibrillation vulnerability via PI3Kγ/SGK1 pathway-dependent M2 macrophage polarisation.
Inhibition of Cxcr4 Disrupts Mouse Embryonic Palatal Mesenchymal Cell Migration and Induces Cleft Palate Occurrence.
S100A4 Promotes BCG-Induced Pyroptosis of Macrophages by Activating the NF-κB/NLRP3 Inflammasome Signaling Pathway.
Shoutai Wan regulates glycolysis imbalance at the maternal-fetal interface in threatened abortion mice.
Ubiquitin-specific protease 7 prevents recurrent spontaneous abortion by targeting enhancer of zeste homolog 2 to regulate trophoblast proliferation, apoptosis, migration, and invasion through the Wnt/β-catenin pathway†.
USP5 promotes lipopolysaccharide-induced apoptosis and inflammatory response by stabilizing the TXNIP protein.
Tumor cells-derived exosomal PD-L1 promotes the growth and invasion of lung cancer cells in vitro via mediating macrophages M2 polarization.
The involvement of let-7 in hCG-induced progesterone synthesis via regulating p27(Kip1) and p21(Cip1) expression.
Apolipoprotein E Polymorphism Impacts White Matter Injury Through Microglial Phagocytosis After Experimental Subarachnoid Hemorrhage.
Preoperative Pain Facilitates Postoperative Cognitive Dysfunction via Periaqueductal Gray Matter-Dorsal Raphe Circuit.
Upregulation of postsynaptic cAMP/PKA/CREB signaling alleviates copper(Ⅱ)-induced oxidative stress and pyroptosis in MN9D cells.
BDE209-promoted Dio2 degradation in H4 glioma cells through the autophagy pathway, resulting in hypothyroidism and leading to neurotoxicity.
Mechanism of aconitine mediated neuronal apoptosis induced by mitochondrial calcium overload caused by MCU.
Ginsenoside Rg1 protects cardiac mitochondrial function via targeting GSTP1 to block S-glutathionylation of optic atrophy 1.
Combination with vorinostat enhances the antitumor activity of cisplatin in castration-resistant prostate cancer by inhibiting DNA damage repair pathway and detoxification of GSH.
BST2 regulated by the transcription factor STAT1 can promote metastasis, invasion and proliferation of oral squamous cell carcinoma via the AKT/ERK1/2 signaling pathway.
Astaxanthin promotes mitochondrial biogenesis and antioxidant capacity in chronic high-intensity interval training.
Bacillus Calmette-Guérin-induced interleukin-10 inhibits S100A8/A9 production and hinders development of T helper type 1 memory in mice.
Irisin attenuates acute lung injury by suppressing the pyroptosis of alveolar macrophages.
Atractylenolide III suppresses senescence-associated secretome via inhibiting cGAS/NF-κB pathway in hepatic stellate cells.
Sufentanil combined with parecoxib sodium inhibits proliferation and metastasis of HER2-positive breast cancer cells and regulates epithelial-mesenchymal transition.
Allogeneic gene-edited HIV-specific CAR-T cells secreting PD-1 blocking scFv enhance specific cytotoxic activity against HIV Env(+) cells invivo.
Parecoxib attenuates inflammation injury in septic H9c2 cells by regulating the MAPK signaling pathway.
Polyamines and eIF5A hypusination facilitate SREBP2 synthesis and cholesterol production leading to enhanced enterovirus attachment and infection.
Exosomes incorporated with black phosphorus quantum dots attenuate retinal angiogenesis via disrupting glucose metabolism.
Ameliorative effects of different doses of selenium against fluoride-triggered apoptosis and oxidative stress-mediated renal injury in rats through the activation of Nrf2/HO-1/NQO1 signaling pathway.
Protective effects of berberine against β-amyloid-induced neurotoxicity in HT22 cells via the Nrf2/HO-1 pathway.
Protective efficacy of Schizandrin B on ameliorating nephrolithiasis via regulating GSK3β/Nrf2 signaling-mediated ferroptosis in vivo and in vitro.
Exploring the effect of polyamines on NK cell function in colorectal cancer process based on glycolysis.
Blockade of neutrophil extracellular traps ameliorates toluene diisocyanate-induced steroid-resistant asthma.
Silencing of OGDHL promotes liver cancer metastasis by enhancing hypoxia inducible factor 1 α protein stability.
Garlic-derived exosomes regulate PFKFB3 expression to relieve liver dysfunction in high-fat diet-fed mice via macrophage-hepatocyte crosstalk.
Tandem mass tag-based quantitative proteomics analysis reveals the effects of the α-lactalbumin peptides GINY and DQW on lipid deposition and oxidative stress in HepG2 cells.
Ccdc25 regulates neurogenesis during the brain development.
Evaluation of Brown Micro-Algae Synergies With Low Dose γ-Radiation Against Chronic Hepatitis Induced by D-Galactosamine in Rats.
Hydrogen peroxide and iron ions can modulate lipid peroxidation, apoptosis, and the cell cycle, but do not have a significant effect on DNA double-strand break.
SCAP contributes to embryonic angiogenesis by negatively regulating KISS-1 expression in mice.
Combination treatment with FAAH inhibitors/URB597 and ferroptosis inducers significantly decreases the growth and metastasis of renal cell carcinoma cells via the PI3K-AKT signaling pathway.
Activation of PPARγ prevents ferroptosis-induced damage through Nrf2/Gpx4 signaling pathway in rat hippocampus following epilepsy.
PGC1α Degradation Suppresses Mitochondrial Biogenesis to Confer Radiation Resistance in Glioma.
Scutellarin Alleviates Ischemic Brain Injury in the Acute Phase by Affecting the Activity of Neurotransmitters in Neurons.
Lovastatin inhibits erythroleukemia progression through KLF2-mediated suppression of MAPK/ERK signaling.
Epitranscriptic regulation of HRAS by N(6)-methyladenosine drives tumor progression.
NMR-Based Metabolic Profiling of the Effects of α-Ketoglutarate Supplementation on Energy-Deficient C2C12 Myotubes.
The Role of LincRNA-EPS/Sirt1/Autophagy Pathway in the Neuroprotection Process by Hydrogen against OGD/R-Induced Hippocampal HT22 Cells Injury.
A novel autophagy-related gene signature associated with prognosis and immune microenvironment in ovarian cancer.
NCAPG is transcriptionally regulated by CBX3 and activates the Wnt/β-catenin signaling pathway to promote proliferation and the cell cycle and inhibit apoptosis in colorectal cancer.
Study on the pharmacological mechanisms of sodium-glucose co-transporter 2 inhibitors in obesity-related atrial fibrillation based on network pharmacology and experimental verification.
RNF123 Mediates Ubiquitination and Degradation of SOCS1 To Regulate Type I Interferon Production during Duck Tembusu Virus Infection.
Single-cell sequencing reveals the immune microenvironment landscape related to anti-PD-1 resistance in metastatic colorectal cancer with high microsatellite instability.
Two-Pore-Domain Potassium Channel TREK-1 Mediates Pulmonary Fibrosis through Macrophage M2 Polarization and by Direct Promotion of Fibroblast Differentiation.
SATB1 regulates 3D genome architecture in T cells by constraining chromatin interactions surrounding CTCF-binding sites.
Butyrate dictates ferroptosis sensitivity through FFAR2-mTOR signaling.
4-Octyl itaconate attenuates LPS-induced acute kidney injury by activating Nrf2 and inhibiting STAT3 signaling.
ATF5 regulates tubulointerstitial injury in diabetic kidney disease via mitochondrial unfolded protein response.
Submersion and hypoxia inhibit alveolar epithelial Na(+) transport through ERK/NF-κB signaling pathway.
Inhibition of mGluR5 ameliorates lipid accumulation and inflammation in HepG2 cells.
High-Dosage NMN Promotes Ferroptosis to Suppress Lung Adenocarcinoma Growth through the NAM-Mediated SIRT1-AMPK-ACC Pathway.
Glucose Starvation Inhibits Ferroptosis by Activating the LKB1/AMPK Signaling Pathway and Promotes the High Speed Linear Motility of Dairy Goat Sperm.
YY1 lactylation in microglia promotes angiogenesis through transcription activation-mediated upregulation of FGF2.
Dose-Dependent Effects in Plasma Oncotherapy: Critical In Vivo Immune Responses Missed by In Vitro Studies.
The emerging role of lysine succinylation in ovarian aging.
Apurinic/apyrimidinic endonuclease 1 regulates palmitic acid-mediated apoptosis in cardiomyocytes via endoplasmic reticulum stress.
Polystyrene Microplastics Induce Oxidative Stress in Mouse Hepatocytes in Relation to Their Size.
Puerarin protects against sepsis-associated encephalopathy by inhibiting NLRP3/Caspase-1/GSDMD pyroptosis pathway and reducing blood-brain barrier damage.
Selenium supplementation enhanced the expression of selenoproteins in hippocampus and played a neuroprotective role in LPS-induced neuroinflammation.
AKR1B1 Represses Glioma Cell Proliferation through p38 MAPK-Mediated Bcl-2/BAX/Caspase-3 Apoptotic Signaling Pathways.
Two Resveratrol Oligomers Inhibit Cathepsin L Activity to Suppress SARS-CoV-2 Entry.
Cytotoxic Steroidal Saponins Containing a Rare Fructosyl from the Rhizomes of Paris polyphylla var. latifolia.
SLC27A2 mediates FAO in colorectal cancer through nongenic crosstalk regulation of the PPARs pathway.
Metformin Collaborates with PINK1/Mfn2 Overexpression to Prevent Cardiac Injury by Improving Mitochondrial Function.
Effects of a ketogenic diet on reproductive and metabolic phenotypes in mice with polycystic ovary syndrome†.
Sea Cucumber Hydrolysate Alleviates Immunosuppression and Gut Microbiota Imbalance Induced by Cyclophosphamide in Balb/c Mice through the NF-κB Pathway.
Proteomic analysis of DZIP3 interactome and its role in proliferation and metastasis in gastric cancer cells.
LINC00365 functions as a tumor suppressor by inhibiting HIF-1α-mediated glucose metabolism reprogramming in breast cancer.
Role of SESTRIN2/AMPK/ULK1 pathway activation and lysosomes dysfunction in NaAsO(2)-induced liver injury under oxidative stress.
Oroxin A ameliorates the oleic acid-induced A549 cell injury through the suppression of pyroptosis and degradation of alveolar surfactant.
Morchella esculenta mushroom polysaccharide attenuates diabetes and modulates intestinal permeability and gut microbiota in a type 2 diabetic mice model.
Deficiency of a novel lncRNA-HRAT protects against myocardial ischemia reperfusion injury by targeting miR-370-3p/RNF41 pathway.
Differential expression pattern, bioinformatics analysis, and validation of circRNA and mRNA in patients with arteriosclerosis.
Gypenosides ameliorate high-fat diet-induced non-alcoholic steatohepatitis via farnesoid X receptor activation.
Effects of Dietary Indole-3-carboxaldehyde Supplementation on Growth Performance, Intestinal Epithelial Function, and Intestinal Microbial Composition in Weaned Piglets.
Integrated Bioinformatic Analysis Reveals TXNRD1 as a Novel Biomarker and Potential Therapeutic Target in Idiopathic Pulmonary Arterial Hypertension.
Deoxythymidylate Kinase as a Promising Marker for Predicting Prognosis and Immune Cell Infiltration of Pan-cancer.
Trans-anethole Ameliorates Intestinal Injury Through Activation of Nrf2 Signaling Pathway in Subclinical Necrotic Enteritis-Induced Broilers.
Human Amnion Epithelial Cells and Their Derived Exosomes Alleviate Sepsis-Associated Acute Kidney Injury via Mitigating Endothelial Dysfunction.
Development and Validation of Novel Prognostic Models for Immune-Related Genes in Osteosarcoma.
Integrated Strategies of Diverse Feature Selection Methods Identify Aging-Based Reliable Gene Signatures for Ischemic Cardiomyopathy.
Identification of Down-Regulated ADH1C is Associated With Poor Prognosis in Colorectal Cancer Using Bioinformatics Analysis.
1α,25-Dihydroxyvitamin D3 Promotes Angiogenesis After Cerebral Ischemia Injury in Rats by Upregulating the TGF-β/Smad2/3 Signaling Pathway.
Senescent renal tubular epithelial cells activate fibroblasts by secreting Shh to promote the progression of diabetic kidney disease.
Dendrobium nobile Lindl. Alkaloids Ameliorate Aβ25-35-Induced Synaptic Deficits by Targeting Wnt/β-Catenin Pathway in Alzheimer's Disease Models.
TRIM47 promotes ovarian cancer cell proliferation, migration, and invasion by activating STAT3 signaling.
Correlation between CDK1 protein and CDK1 mRNA during oocyte maturation in mouse.
Wheat oligopeptides enhance the intestinal mucosal barrier and alleviate inflammation via the TLR4/Myd88/MAPK signaling pathway in aged mice.
MiR-328-5p inhibits the adipogenic differentiation of hMSCs by targeting fatty acid synthase.
Tooth Loss Induces Memory Impairment and Glial Activation in Young Wild-Type Mice.
Naringin regulates mitochondrial dynamics to protect against acetaminophen-induced hepatotoxicity by activating the AMPK/Nrf2 signaling pathway in vitro.
Benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide induces ferroptosis in neuroblastoma cells through redox imbalance.
Evacetrapib Elicits Antitumor Effects on Colorectal Cancer by Inhibiting the Wnt/β-Catenin Signaling Pathway and Activating the JNK Signaling Pathway.
KIAA1199 Correlates With Tumor Microenvironment and Immune Infiltration in Lung Adenocarcinoma as a Potential Prognostic Biomarker.
Corrigendum to "Berberine Reduces Renal Cell Pyroptosis in Golden Hamsters with Diabetic Nephropathy through the Nrf2-NLRP3-Caspase-1-GSDMD Pathway".
IL-22 Protects against Biliary Ischemia-Reperfusion Injury after Liver Transplantation via Activating STAT3 and Reducing Apoptosis and Oxidative Stress Levels In Vitro and In Vivo.
The Effective Analysis for Blue Honeysuckle Extract in the Treatment of Hepatocellular Carcinoma.
Actin-Binding LIM 1 (ABLIM1) Inhibits Glioblastoma Progression and Serves as a Novel Prognostic Biomarker.
DNA Methyltransferase Inhibitor 5-AZA-DC Regulates TGFβ1-Mediated Alteration of Neuroglial Cell Functions after Oxidative Stress.
Artesunate Suppresses the Growth of Lung Cancer Cells by Downregulating the AKT/Survivin Signaling Pathway.
HBO Alleviates Neural Stem Cell Pyroptosis via lncRNA-H19/miR-423-5p/NLRP3 Axis and Improves Neurogenesis after Oxygen Glucose Deprivation.
Ginsenoside Rg1 Inhibits STAT3 Expression by miR-15b-5p to Attenuate Lung Injury in Mice with Type 2 Diabetes Mellitus-Associated Pulmonary Tuberculosis.
Inhibitory Effects of Parachlorella Beijerinckii Extracts on the Formation of Advanced Glycation End Products and Glycative Stress-Induced Inflammation in an In Vitro Skin Dermis-Like Model.
Cystathionine β-Synthase Regulates the Proliferation, Migration, and Invasion of Thyroid Carcinoma Cells.
Loureirin A Exerts Antikeloid Activity by Antagonizing the TGF-β1/Smad Signalling Pathway.
Dl-3-n-Butylphthalide Improves Neuroinflammation in Mice with Repeated Cerebral Ischemia-Reperfusion Injury through the Nrf2-Mediated Antioxidant Response and TLR4/MyD88/NF-κB Signaling Pathway.
Preliminary Evaluation of Artificial Intelligence-Based Anti-Hepatocellular Carcinoma Molecular Target Study in Hepatocellular Carcinoma Diagnosis Research.
Activation of PPARγ Protects Obese Mice from Acute Lung Injury by Inhibiting Endoplasmic Reticulum Stress and Promoting Mitochondrial Biogenesis.
Recurrent Hypoglycemia Impaired Vascular Function in Advanced T2DM Rats by Inducing Pyroptosis.
Hypoxia-Induced miR-210 Promotes Endothelial Cell Permeability and Angiogenesis via Exosomes in Pancreatic Ductal Adenocarcinoma.
Effect of Thymoquinone on Renal Damage Induced by Hyperlipidemia in LDL Receptor-Deficient (LDL-R(-)/(-)) Mice.
Astragali Radix-Coptis Rhizoma Herb Pair Attenuates Atherosclerosis in ApoE-/- Mice by Regulating the M1/M2 and Th1/Th2 Immune Balance and Activating the STAT6 Signaling Pathway.
TLR4 Modulates Senescence and Paracrine Action in Placental Mesenchymal Stem Cells via Inhibiting Hedgehog Signaling Pathway in Preeclampsia.
Rhein Inhibits the Progression of Chemoresistant Lung Cancer Cell Lines via the Stat3/Snail/MMP2/MMP9 Pathway.
Transmissible Endoplasmic Reticulum Stress Mediated by Extracellular Vesicles from Adipocyte Promoting the Senescence of Adipose-Derived Mesenchymal Stem Cells in Hypertrophic Obesity.
Silencing CAMK2D Promotes the Proliferation of Spermatogonia in the Testis of Experimental Varicocele Rats.
EGCG Enhances the Chemosensitivity of Colorectal Cancer to Irinotecan through GRP78-MediatedEndoplasmic Reticulum Stress.
Protection of Human Lens Epithelial Cells from Oxidative Stress Damage and Cell Apoptosis by KGF-2 through the Akt/Nrf2/HO-1 Pathway.
Inhibition of Bruton's Tyrosine Kinase Alleviates Monocrotaline-Induced Pulmonary Arterial Hypertension by Modulating Macrophage Polarization.
Multifunctional Drug-Loaded Phase-Change Nanoparticles Inhibit the Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma by Affecting the Activity of Activated Hepatic Stellate Cells.
Therapeutic Potential of Synthetic Human β-Defensin 1 Short Motif Pep-B on Lipopolysaccharide-Stimulated Human Dental Pulp Stem Cells.
ProNGF/NGF Modulates Autophagy and Apoptosis through PI3K/Akt/mTOR and ERK Signaling Pathways following Cerebral Ischemia-Reperfusion in Rats.
Inhibition of APE1 Expression Enhances the Antitumor Activity of Olaparib in Triple-Negative Breast Cancer.
Magnesium Hydride Ameliorates Endotoxin-Induced Acute Respiratory Distress Syndrome by Inhibiting Inflammation, Oxidative Stress, and Cell Apoptosis.
Saikosaponin D Inducing Apoptosis and Autophagy through the Activation of Endoplasmic Reticulum Stress in Glioblastoma.
The Effects of Hedgehog Signaling Pathway on the Proliferation and Apoptosis of Melanoma Cells.
Downregulation of FXYD2 Is Associated with Poor Prognosis and Increased Regulatory T Cell Infiltration in Clear Cell Renal Cell Carcinoma.
Melatonin Alleviates Acute Kidney Injury by Inhibiting NRF2/Slc7a11 Axis-Mediated Ferroptosis.
Sodium Butyrate Attenuated Diabetes-Induced Intestinal Inflammation by Modulating Gut Microbiota.
Evodiamine as the Active Compound of Evodiae fructus to Inhibit Proliferation and Migration of Prostate Cancer through PI3K/AKT/NF-κB Signaling Pathway.
IL6 Induces mtDNA Leakage to Affect the Immune Escape of Endometrial Carcinoma via cGAS-STING.
Molecular Hydrogen Reduces Electromagnetic Pulse-Induced Male Rat Reproductive System Damage in a Rodent Model.
Mulberry Leaf Flavonoids Inhibit Liver Inflammation in Type 2 Diabetes Rats by Regulating TLR4/MyD88/NF-κB Signaling Pathway.
Theaflavin-3,3'-Digallate Protects Cartilage from Degradation by Modulating Inflammation and Antioxidant Pathways.
San-Huang-Yi-Shen Capsule Ameliorates Diabetic Kidney Disease through Inducing PINK1/Parkin-Mediated Mitophagy and Inhibiting the Activation of NLRP3 Signaling Pathway.
Grape Seed Proanthocyanidins Exert a Neuroprotective Effect by Regulating Microglial M1/M2 Polarisation in Rats with Spinal Cord Injury.
β-Carotene Attenuates Apoptosis and Autophagy via PI3K/AKT/mTOR Signaling Pathway in Necrotizing Enterocolitis Model Cells IEC-6.
Geraniin Protects against Cerebral Ischemia/Reperfusion Injury by Suppressing Oxidative Stress and Neuronal Apoptosis via Regulation of the Nrf2/HO-1 Pathway.
Identification and Validation of a Prognostic Signature Based on Methylation Profiles and Methylation-Driven Gene DAB2 as a Prognostic Biomarker in Differentiated Thyroid Carcinoma.
Diet-Induced High Serum Levels of Trimethylamine-N-oxide Enhance the Cellular Inflammatory Response without Exacerbating Acute Intracerebral Hemorrhage Injury in Mice.
Maternal Inflammation Exaggerates Offspring Susceptibility to Cerebral Ischemia-Reperfusion Injury via the COX-2/PGD2/DP(2) Pathway Activation.
Liensinine Inhibits Cell Growth and Blocks Autophagic Flux in Nonsmall-Cell Lung Cancer.
Acupuncture Effect Assessment in APP/PS1 Transgenic Mice: On Regulating Learning-Memory Abilities, Gut Microbiota, and Microbial Metabolites.
Maltol Promotes Mitophagy and Inhibits Oxidative Stress via the Nrf2/PINK1/Parkin Pathway after Spinal Cord Injury.
Xiao-Chai-Hu Decoction Ameliorates Poly (I:C)-Induced Viral Pneumonia through Inhibiting Inflammatory Response and Modulating Serum Metabolism.
Altered gene expression in human brain microvascular endothelial cells in response to the infection of influenza H1N1 virus.
High-mobility Group Box 1 Contributes to Hypoxic-Ischemic Brain Damage by Facilitating Imbalance of Microglial Polarization through RAGE-PI3K/Akt Pathway in Neonatal Rats.
A marine-derived small molecule induces immunogenic cell death against triple-negative breast cancer through ER stress-CHOP pathway.
BMAL1 regulates Propionibacterium acnes-induced skin inflammation via REV-ERBα in mice.
Low expression of microRNA-125b enhances the expression of STAT3 and contributes to cholesteatoma growth.
RBMS2 Chemosensitizes Breast Cancer Cells to Doxorubicin by Regulating BMF Expression.
The lncRNA BDNF-AS/WDR5/FBXW7 axis mediates ferroptosis in gastric cancer peritoneal metastasis by regulating VDAC3 ubiquitination.
HJURP Promotes Malignant Progression and Mediates Sensitivity to Cisplatin and WEE1-inhibitor in Serous Ovarian Cancer.
HNRNPK/CLCN3 axis facilitates the progression of LUAD through CAF-tumor interaction.
Anp32e promotes renal interstitial fibrosis by upregulating the expression of fibrosis-related proteins.
Psychosocial stress and cannabinoid drugs affect acetylation of α-tubulin (K40) and gene expression in the prefrontal cortex of adult mice.
Decitabine attenuates ischemic stroke by reducing astrocytes proliferation in rats.
RETRACTED: Zoledronic acid generates a spatiotemporal effect to attenuate osteoarthritis by inhibiting potential Wnt5a-associated abnormal subchondral bone resorption.
Concomitant pyroptotic and apoptotic cell death triggered in macrophages infected by Zika virus.
Gut microbiota and butyrate contribute to nonalcoholic fatty liver disease in premenopause due to estrogen deficiency.
Alzheimer's risk factor FERMT2 promotes the progression of colorectal carcinoma via Wnt/β-catenin signaling pathway and contributes to the negative correlation between Alzheimer and cancer.
miR-186-5p Dysregulation in Serum Exosomes from Patients with AMI Aggravates Atherosclerosis via Targeting LOX-1.
The neural stem cell properties of Pkd2l1(+) cerebrospinal fluid-contacting neurons in vivo.
Decreased tubulin-binding cofactor B was involved in the formation disorder of nascent astrocyte processes by regulating microtubule plus-end growth through binding with end-binding proteins 1 and 3 after chronic alcohol exposure.
Identification of key genes and pathways revealing the central regulatory mechanism of brain-derived glucagon-like peptide-1 on obesity using bioinformatics analysis.
Ketamine Attenuates Airway Inflammation via Inducing Inflammatory Cells Apoptosis and Activating Nrf2 Pathway in a Mixed-Granulocytic Murine Asthma Model.
Canagliflozin Attenuates Hepatic Steatosis and Atherosclerosis Progression in Western Diet-Fed ApoE-Knockout Mice.
Feasibility of Catalpol Intranasal Administration and Its Protective Effect on Acute Cerebral Ischemia in Rats via Anti-Oxidative and Anti-Apoptotic Mechanisms.
Analysis of the expression and distribution of protein O-linked mannose β1,2-N-acetylglucosaminyltransferase 1 in the normal adult mouse brain.
The Effect and Mechanism of Duodenal-Jejunal Bypass to Treat Type 2 Diabetes Mellitus in a Rat Model.
Ras-related protein Rab-20 inhibition alleviates cerebral ischemia/reperfusion injury by inhibiting mitochondrial fission and dysfunction.
Genetic Deficiency of p53 Leads to Structural, Functional, and Synaptic Deficits in Primary Somatosensory Cortical Neurons of Adult Mice.
Receptor-Interacting Protein Kinase 3 Inhibition Relieves Mechanical Allodynia and Suppresses NLRP3 Inflammasome and NF-κB in a Rat Model of Spinal Cord Injury.
NF-κB and AP-1 are required for the lipopolysaccharide-induced expression of MCP-1, CXCL1, and Cx43 in cultured rat dorsal spinal cord astrocytes.
Apelin-13 Attenuates Lipopolysaccharide-Induced Inflammatory Responses and Acute Lung Injury by Regulating PFKFB3-Driven Glycolysis Induced by NOX4-Dependent ROS.
The inhibition of PGAM5 suppresses seizures in a kainate-induced epilepsy model via mitophagy reduction.
Involvement of hedgehog signaling in all-trans retinoic acid-mediated suppression of colon cancer.
miR-153-3p inhibits osteogenic differentiation of BMSCs by down-regulating the expression of RUNX2 in a high glucose environment.
Macrophage SCAP Contributes to Metaflammation and Lean NAFLD by Activating STING-NF-κB Signaling Pathway.
KLF16 Downregulates the Expression of Tumor Suppressor Gene TGFBR3 to Promote Bladder Cancer Proliferation and Migration.
Effect of β-hydroxybutyrate on behavioral alterations, molecular and morphological changes in CNS of multiple sclerosis mouse model.
1,25-D3 attenuates cerebral ischemia injury by regulating mitochondrial metabolism via the AMPK/AKT/GSK3β pathway.
Impact prediction of translocation of the mitochondrial outer membrane 70 as biomarker in Alzheimer's disease.
Transcriptional and H3K27ac related genome profiles in oral squamous cell carcinoma cells treated with metformin.
Silencing LINC00491 Inhibits Pancreatic Cancer Progression through MiR-188-5p-induced Inhibition of ZFP91.
Sinapine Thiocyanate Inhibits the Proliferation and Mobility of Pancreatic Cancer Cells by Up-Regulating GADD45A.
Niban apoptosis regulator 1 promotes gemcitabine resistance by activating the focal adhesion kinase signaling pathway in bladder cancer.
PERK Regulates the Sensitivity of Hepatocellular Carcinoma Cells to High-LET Carbon Ions via either Apoptosis or Ferroptosis.
LHPP suppresses gastric cancer progression via the PI3K/AKT/mTOR signaling pathway.
Analysis of the absorbed constituents and mechanism of liquidambaris fructus extract on hepatocellular carcinoma.
CaM/CaMKII mediates activation and proliferation of hepatic stellate cells regulated by ASIC1a.
A prognostic signature consisting of metabolism-related genes and SLC17A4 serves as a potential biomarker of immunotherapeutic prediction in prostate cancer.
Bu-Gu-Sheng-Sui decoction promotes osteogenesis via activating the ERK/Smad signaling pathways.
Alleviating effect of quercetin on cadmium-induced oxidative damage and apoptosis by activating the Nrf2-keap1 pathway in BRL-3A cells.
Paeoniflorin directly binds to TNFR1 to regulate podocyte necroptosis in diabetic kidney disease.
Inhibition of calpain9 attenuates peritoneal dialysis-related peritoneal fibrosis.
Reduced binding activity of vaccine serum to omicron receptor-binding domain.
Sanguinarine protects against indomethacin-induced small intestine injury in rats by regulating the Nrf2/NF-κB pathways.
Poldip2 knockdown protects against lipopolysaccharide-induced acute lung injury via Nox4/Nrf2/NF-κB signaling pathway.
Construction, bioinformatics analysis, and validation of competitive endogenous RNA networks in ulcerative colitis.
Puffball spores improve wound healing in a diabetic rat model.
Identifying potential prognosis markers in hepatocellular carcinoma via integrated bioinformatics analysis and biological experiments.
Melatonin promotes sirtuin 1 expression and inhibits IRE1α-XBP1S-CHOP to reduce endoplasmic reticulum stress-mediated apoptosis in chondrocytes.
Ferredoxin 1 is a cuproptosis-key gene responsible for tumor immunity and drug sensitivity: A pan-cancer analysis.
Polysaccharide, the Active Component of Dendrobium officinale, Ameliorates Metabolic Hypertension in Rats via Regulating Intestinal Flora-SCFAs-Vascular Axis.
Identification of oncogenes and tumor-suppressor genes with hepatocellular carcinoma: A comprehensive analysis based on TCGA and GEO datasets.
D-tagatose protects against oleic acid-induced acute respiratory distress syndrome in rats by activating PTEN/PI3K/AKT pathway.
Acetyl-11-Keto-Beta Boswellic Acid (AKBA) Protects Lens Epithelial Cells Against H(2)O(2)-Induced Oxidative Injury and Attenuates Cataract Progression by Activating Keap1/Nrf2/HO-1 Signaling.
Protective effect of Astragaloside IV on chronic intermittent hypoxia-induced vascular endothelial dysfunction through the calpain-1/SIRT1/AMPK signaling pathway.
β-elemene Isopropanolamine Derivative LXX-8250 Induces Apoptosis Through Impairing Autophagic Flux via PFKFB4 Repression in Melanoma Cells.
EspF of Enterohemorrhagic Escherichia coli Enhances Apoptosis via Endoplasmic Reticulum Stress in Intestinal Epithelial Cells: An Isobaric Tags for Relative and Absolute Quantitation-Based Comparative Proteomic Analysis.
Chronic constant light exposure aggravates high fat diet-induced renal injury in rats.
Evaluation of decompressive craniectomy in mice after severe traumatic brain injury.
Olanzapine-induced lipid disturbances: A potential mechanism through the gut microbiota-brain axis.
Interleukin-6-derived cancer-associated fibroblasts activate STAT3 pathway contributing to gemcitabine resistance in cholangiocarcinoma.
Melatonin prevents cyclophosphamide-induced primordial follicle loss by inhibiting ovarian granulosa cell apoptosis and maintaining AMH expression.
Optineurin-mediated mitophagy as a potential therapeutic target for intervertebral disc degeneration.
Phyllanthus Niruri L. Exerts Protective Effects Against the Calcium Oxalate-Induced Renal Injury via Ellgic Acid.
High expression of B4GALT1 is associated with poor prognosis in acute myeloid leukemia.
Pan-Cancer Analysis of the Immunological Role of PDIA5: A Potential Target for Immunotherapy.
Novel Antiviral Activity of Ethyl 3-Hydroxyhexanoate Against Coxsackievirus B Infection.
Liraglutide Attenuates Hepatic Ischemia-Reperfusion Injury by Modulating Macrophage Polarization.
Arachidonic Acid in Follicular Fluid of PCOS Induces Oxidative Stress in a Human Ovarian Granulosa Tumor Cell Line (KGN) and Upregulates GDF15 Expression as a Response.
Effects of Xiao Chengqi Formula on Slow Transit Constipation by Assessing Gut Microbiota and Metabolomics Analysis in vitro and in vivo.
MiR-103a-3p Promotes Zika Virus Replication by Targeting OTU Deubiquitinase 4 to Activate p38 Mitogen-Activated Protein Kinase Signaling Pathway.
Identification of cytochrome c oxidase subunit 4 isoform 1 as a positive regulator of influenza virus replication.
Comprehensive Analysis of the Potential Immune-Related Biomarker ATG101 that Regulates Apoptosis of Cholangiocarcinoma Cells After Photodynamic Therapy.
Kaempferol From Penthorum chinense Pursh Attenuates Hepatic Ischemia/Reperfusion Injury by Suppressing Oxidative Stress and Inflammation Through Activation of the Nrf2/HO-1 Signaling Pathway.
Munronoid I Ameliorates DSS-Induced Mouse Colitis by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis Via Modulation of NLRP3.
Quercetin Attenuates Osteoporosis in Orchiectomy Mice by Regulating Glucose and Lipid Metabolism via the GPRC6A/AMPK/mTOR Signaling Pathway.
Vitamin D Deficiency Impacts Exposure and Response of Pravastatin in Male Rats by Altering Hepatic OATPs.
Heat Stress Modulates a Placental Immune Response Associated With Alterations in the Development of the Fetal Intestine and Its Innate Immune System in Late Pregnant Mouse.
Identification of an autophagy-related 12-lncRNA signature and evaluation of NFYC-AS1 as a pro-cancer factor in lung adenocarcinoma.
Trans-Anethole Alleviates Subclinical Necro-Haemorrhagic Enteritis-Induced Intestinal Barrier Dysfunction and Intestinal Inflammation in Broilers.
Dehydrocostus Lactone Suppresses Dextran Sulfate Sodium-Induced Colitis by Targeting the IKKα/β-NF-κB and Keap1-Nrf2 Signalling Pathways.
Didymin Suppresses Microglia Pyroptosis and Neuroinflammation Through the Asc/Caspase-1/GSDMD Pathway Following Experimental Intracerebral Hemorrhage.
Avasimibe Alleviates Disruption of the Airway Epithelial Barrier by Suppressing the Wnt/β-Catenin Signaling Pathway.
Long Noncoding RNA Metastasis-Associated Lung Adenocarcinoma Transcript 1 in Extracellular Vesicles Promotes Hepatic Stellate Cell Activation, Liver Fibrosis and β-Catenin Signaling Pathway.
Chemerin Regulates the Proliferation and Migration of Pulmonary Arterial Smooth Muscle Cells via the ERK1/2 Signaling Pathway.
Alpha-Asaronol Alleviates Dysmyelination by Enhancing Glutamate Transport Through the Activation of PPARγ-GLT-1 Signaling in Hypoxia-Ischemia Neonatal Rats.
Pectin supplement alleviates gut injury potentially through improving gut microbiota community in piglets.
A positive feedback loop of the TAZ/β-catenin axis promotes Helicobacter pylori-associated gastric carcinogenesis.
Corilagin alleviates intestinal ischemia/reperfusion-induced intestinal and lung injury in mice via inhibiting NLRP3 inflammasome activation and pyroptosis.
Vam6 reduces iNKT cell function in tumor via modulating AMPK/mTOR pathways.
Systematic pan-cancer analysis identifies RALA as a tumor targeting immune therapeutic and prognostic marker.
P53 maintains gallid alpha herpesvirus 1 replication by direct regulation of nucleotide metabolism and ATP synthesis through its target genes.
Oxaloacetate acid ameliorates paraquat-induced acute lung injury by alleviating oxidative stress and mitochondrial dysfunction.
Berberine prevents lethal EV71 neurological infection in newborn mice.
Matrine, a potential c-Myc inhibitor, suppresses ribosome biogenesis and nucleotide metabolism in myeloid leukemia.
Acute hypoxia induced dysregulation of clock-controlled ovary functions.
Shuangyu Tiaozhi decoction alleviates non-alcoholic fatty liver disease by improving lipid deposition, insulin resistance, and inflammation in vitro and in vivo.
Network pharmacology-based and experimental identification of the effects of Renshen Yangrong decoction on myocardial infarction.
Effect of transferrin glycation induced by high glucose on HK-2 cells in vitro.
Salvianolic acid A regulates pyroptosis of endothelial cells via directly targeting PKM2 and ameliorates diabetic atherosclerosis.
Optimized mobilization of MHC class I- and II- restricted immunity by dendritic cell vaccine potentiates cancer therapy.
Non-invasive photobiomodulation treatment in an Alzheimer Disease-like transgenic rat model.
Lgr5 (+) cell fate regulation by coordination of metabolic nuclear receptors during liver repair.
Continuous theta-burst stimulation enhances and sustains neurogenesis following ischemic stroke.
POLD2 is activated by E2F1 to promote triple-negative breast cancer proliferation.
Novel LncRNA ZFHX4-AS1 as a Potential Prognostic Biomarker That Affects the Immune Microenvironment in Ovarian Cancer.
GPR12 Inhibits Apoptosis in Epithelial Ovarian Cancer via the Activation of ERK1/2 Signaling.
Reduction of H3K27cr Modification During DNA Damage in Colon Cancer.
Isolation, characterization, and functional study of extracellular vesicles derived from Leishmania tarentolae.
Glia Maturation Factor β as a Novel Independent Prognostic Biomarker and Potential Therapeutic Target of Kidney Renal Clear Cell Carcinoma.
Nrf2 Overexpression Decreases Vincristine Chemotherapy Sensitivity Through the PI3K-AKT Pathway in Adult B-Cell Acute Lymphoblastic Leukemia.
OCT4 induces EMT and promotes ovarian cancer progression by regulating the PI3K/AKT/mTOR pathway.
Integrated Network Pharmacology and Experimental Verification to Explore the Molecular Mechanism of Hedysarum Multijugum Maxim-Curcumae Rhizoma Herb Pair for Treating Non-Small Cell Lung Cancer.
The hnRNPK/A1/R/U Complex Regulates Gene Transcription and Translation and is a Favorable Prognostic Biomarker for Human Colorectal Adenocarcinoma.
The Long Non-Coding RNA HOXC-AS3 Promotes Glioma Progression by Sponging miR-216 to Regulate F11R Expression.
CD147 Mediates 5-Fluorouracil Resistance in Colorectal Cancer by Reprogramming Glycolipid Metabolism.
Neutrophils Promote Tumor Progression in Oral Squamous Cell Carcinoma by Regulating EMT and JAK2/STAT3 Signaling Through Chemerin.
Ciclopirox Olamine Exerts Tumor-Suppressor Effects via Topoisomerase II Alpha in Lung Adenocarcinoma.
The oral microbiome in young women at different stages of periodontitis: Prevotella dominant in stage III periodontitis.
Dual-fluorescent reporter for live-cell imaging of the ER during DENV infection.
Genome-wide association studies identify miRNA-194 as a prognostic biomarker for gastrointestinal cancer by targeting ATP6V1F, PPP1R14B, BTF3L4 and SLC7A5.
Consistent downregulation of the cleft lip/palate-associated genes IRF6 and GRHL3 in carcinomas.
Reversion of methionine addiction of osteosarcoma cells to methionine independence results in loss of malignancy, modulation of the epithelial-mesenchymal phenotype and alteration of histone-H3 lysine-methylation.
Cinnamic Acid Improved Lipopolysaccharide-Induced Depressive-Like Behaviors by Inhibiting Neuroinflammation and Oxidative Stress in Mice.
PIN1 protects auditory hair cells from senescence via autophagy.
Overexpression of LINC00551 promotes autophagy-dependent ferroptosis of lung adenocarcinoma via upregulating DDIT4 by sponging miR-4328.
G3BP2, a stress granule assembly factor, is dispensable for spermatogenesis in mice.
Ferulic acid attenuates high glucose-induced apoptosis in retinal pigment epithelium cells and protects retina in db/db mice.
Icaritin attenuates 6-OHDA-induced MN9D cell damage by inhibiting oxidative stress.
Dexamethasone Alleviates Myocardial Injury in a Rat Model of Acute Myocardial Infarction Supported by Venoarterial Extracorporeal Membrane Oxygenation.
CircFGGY Inhibits Cell Growth, Invasion and Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma via Regulating the miR-545-3p/Smad7 Axis.
Poloxamer 407 and Hyaluronic Acid Thermosensitive Hydrogel-Encapsulated Ginsenoside Rg3 to Promote Skin Wound Healing.
Mechanical Stimulation Protects Against Chondrocyte Pyroptosis Through Irisin-Induced Suppression of PI3K/Akt/NF-κB Signal Pathway in Osteoarthritis.
Effect of condylar chondrocyte exosomes on condylar cartilage osteogenesis in rats under tensile stress.
The single-atom iron nanozyme mimicking peroxidase remodels energy metabolism and tumor immune landscape for synergistic chemodynamic therapy and photothermal therapy of triple-negative breast cancer.
Influenza virus NS1 interacts with 14-3-3ε to antagonize the production of RIG-I-mediated type I interferons.
Calycosin suppresses colorectal cancer progression by targeting ERβ, upregulating PTEN, and inhibiting PI3K/Akt signal pathway.
Ginsenoside Rg3 increases gemcitabine sensitivity of pancreatic adenocarcinoma via reducing ZFP91 mediated TSPYL2 destabilization.
Puerarin-V prevents the progression of hypoxia- and monocrotaline-induced pulmonary hypertension in rodent models.
Analgesic effect of nobiletin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
Interleukin 32 participates in cardiomyocyte-induced oxidative stress, inflammation and apoptosis during hypoxia/reoxygenation via the NOD2/NOX2/MAPK signaling pathway.
Grifola frondosa Polysaccharide Ameliorates Early Diabetic Nephropathy by Suppressing the TLR4/NF-κB Pathway.
Hydrogen gas promotes apoptosis of lung adenocarcinoma A549 cells through X-linked inhibitor of apoptosis and baculoviral inhibitor of apoptosis protein repeat-containing 3.
Substitution of SERCA2 Cys(674) accelerates aortic aneurysm by inducing endoplasmic reticulum stress and promoting cell apoptosis.
Tubuloside B, isolated from Cistanche tubulosa, a promising agent against M1 macrophage activation via synergistically targeting Mob1 and ERK1/2.
LARP6 Regulates Keloid Fibroblast Proliferation, Invasion, and Ability to Synthesize Collagen.
Anti-inflammatory effect of Bifidobacterium animalis subsp. lactis A6 on DSS-induced colitis in mice.
MiR-1306-5p promotes cell proliferation and inhibits cell apoptosis in acute myeloid leukemia by downregulating PHF6 expression.
Magnoflorine attenuates inflammatory responses in RA by regulating the PI3K/Akt/NF-κB and Keap1-Nrf2/HO-1 signalling pathways in vivo and in vitro.
BRD7 restrains TNF-α-induced proliferation and migration of airway smooth muscle cells by inhibiting notch signaling.
A deafness-associated mitochondrial DNA mutation caused pleiotropic effects on DNA replication and tRNA metabolism.
Proteomic and Biochemical Approaches Elucidate the Role of Millimeter-Wave Irradiation in Wheat Growth under Flooding Stress.
Discovery and characterization of heterogeneous and multipotent fibroblast populations isolated from excised cleft lip tissue.
Down-Regulation of Double C2 Domain Alpha Promotes the Formation of Hyperplastic Nerve Fibers in Aganglionic Segments of Hirschsprung's Disease.
TRIM36 inhibits tumorigenesis through the Wnt/β-catenin pathway and promotes caspase-dependent apoptosis in hepatocellular carcinoma.
LINC00839 promotes colorectal cancer progression by recruiting RUVBL1/Tip60 complexes to activate NRF1.
Zika virus alters centrosome organization to suppress the innate immune response.
A 3D-printed molybdenum-containing scaffold exerts dual pro-osteogenic and anti-osteoclastogenic effects to facilitate alveolar bone repair.
Spermidine protects against acute kidney injury by modulating macrophage NLRP3 inflammasome activation and mitochondrial respiration in an eIF5A hypusination-related pathway.
Gasdermin D is involved in switching from apoptosis to pyroptosis in TLR4-mediated renal tubular epithelial cells injury in diabetic kidney disease.
Combinatorial approaches for mitigating resistance to KRAS-targeted therapies.
Disulfiram alleviates pristane-induced lupus via inhibiting GSDMD-mediated pyroptosis.
Morchella esculenta polysaccharide attenuate obesity, inflammation and modulate gut microbiota.
Moxidectin induces autophagy arrest in colorectal cancer.
A New Long Noncoding RNA, MAHAT, Inhibits Replication of Porcine Reproductive and Respiratory Syndrome Virus by Recruiting DDX6 To Bind to ZNF34 and Promote an Innate Immune Response.
Duck Tembusu Virus Inhibits Type I Interferon Production through the JOSD1-SOCS1-IRF7 Negative-Feedback Regulation Pathway.
Apelin-13 reduces lipopolysaccharide-induced neuroinflammation and cognitive impairment via promoting glucocorticoid receptor expression and nuclear translocation.
Downregulation of miR-30b-5p Facilitates Chondrocyte Hypertrophy and Apoptosis via Targeting Runx2 in Steroid-Induced Osteonecrosis of the Femoral Head.
A homozygous PIWIL2 frameshift variant affects the formation and maintenance of human-induced pluripotent stem cell-derived spermatogonial stem cells and causes Sertoli cell-only syndrome.
Realgar Alleviated Neuroinflammation Induced by High Protein and High Calorie Diet in Rats via the Microbiota-Gut-Brain Axis.
Probing the Potential Mechanism of Quercetin and Kaempferol against Heat Stress-Induced Sertoli Cell Injury: Through Integrating Network Pharmacology and Experimental Validation.
Daidzein alleviates doxorubicin-induced heart failure via the SIRT3/FOXO3a signaling pathway.
Genistein Restricts the Epithelial Mesenchymal Transformation (EMT) and Stemness of Hepatocellular Carcinoma via Upregulating miR-1275 to Inhibit the EIF5A2/PI3K/Akt Pathway.
Inhibition of cannabinoid receptor type 1 sensitizes triple-negative breast cancer cells to ferroptosis via regulating fatty acid metabolism.
Colletofragarone A2 Inhibits Cancer Cell Growth In Vivo and Leads to the Degradation and Aggregation of Mutant p53.
Effect of crude polysaccharide from seaweed, Dictyopteris divaricata (CDDP) on gut microbiota restoration and anti-diabetic activity in streptozotocin (STZ)-induced T1DM mice.
Curcumin regulates anti-inflammatory responses by AXL/JAK2/STAT3 signaling pathway in experimental autoimmune encephalomyelitis.
Endothelial cells regulated by RNF20 orchestrate the proliferation and differentiation of neural precursor cells during embryonic development.
Senescent Phenotype of Astrocytes Leads to Activation of BV2 Microglia and N2a Neuronal Cells Death.
Placental expression of estrogen-related receptor gamma is reduced in fetal growth restriction pregnancies and is mediated by hypoxia†.
Glycogen metabolism reprogramming promotes inflammation in coal dust-exposed lung.
Phellinus linteus polysaccharides mediates acetaminophen-induced hepatotoxicity via activating AMPK/Nrf2 signaling pathways.
FTO-dependent N(6)-Methyladenosine regulates the progression of endometriosis via the ATG5/PKM2 Axis.
New Deferric Amine Compounds Efficiently Chelate Excess Iron to Treat Iron Overload Disorders and to Prevent Ferroptosis.
Palmitoylation of MDH2 by ZDHHC18 activates mitochondrial respiration and accelerates ovarian cancer growth.
High expression of eIF4A1 predicts unfavorable prognosis in clear cell renal cell carcinoma.
Glibenclamide Directly Prevents Neuroinflammation by Targeting SUR1-TRPM4-Mediated NLRP3 Inflammasome Activation In Microglia.
HDAC6 Inhibition Alleviates Anesthesia and Surgery-Induced Less Medial Prefrontal-Dorsal Hippocampus Connectivity and Cognitive Impairment in Aged Rats.
High expression of Sam68 contributes to metastasis by regulating vimentin expression and a motile phenotype in oral squamous cell carcinoma.
Exogenous TIPE2 Inhibit TAK1 to Improve Inflammation and Neuropathic Pain Induced by Sciatic Nerve Injury Through Inactivating NF-κB and JNK.
Yajieshaba prevents lipopolysaccharide-induced intestinal barrier injuryanti-inflammatory and anti-apoptosis.
Identification of Trovafloxacin, Ozanimod, and Ozenoxacin as Potent c-Myc G-Quadruplex Stabilizers to Suppress c-Myc Transcription and Myeloma Growth.
CDGSH iron sulfur domain 2 mitigates apoptosis, oxidative stress and inflammatory response caused by oxygen-glucose deprivation/reoxygenation in HT22 hippocampal neurons by Akt-Nrf2-activated pathway.
Pirh2 restricts influenza A virus replication by modulating short-chain ubiquitination of its nucleoprotein.
A single-beam of light priming the immune responses and boosting cancer photoimmunotherapy.
Organophosphate flame retardant TDCPP: A risk factor for renal cancer?
Upregulation of Wilms' Tumor 1 in epicardial cells increases cardiac fibrosis in dystrophic mice.
Effects of intraperitoneal injection of lipopolysaccharide-induced peripheral inflammation on dopamine neuron damage in rat midbrain.
SNORA70E promotes the occurrence and development of ovarian cancer through pseudouridylation modification of RAP1B and alternative splicing of PARPBP.
IMP075 targeting ClpP for colon cancer therapy in vivo and in vitro.
Angiotensin II type-2 receptor activation in alveolar macrophages mediates protection against cigarette smoke-induced chronic obstructive pulmonary disease.
Substitution of the SERCA2 Cys(674) reactive thiol accelerates atherosclerosis by inducing endoplasmic reticulum stress and inflammation.
CD137 Signal Mediates Cardiac Ischemia-Reperfusion Injury by Regulating the Necrosis of Cardiomyocytes.
OAS1, OAS2, and OAS3 Contribute to Epidermal Keratinocyte Proliferation by Regulating Cell Cycle and Augmenting IFN-1‒Induced Jak1‒Signal Transducer and Activator of Transcription 1 Phosphorylation in Psoriasis.
Prenatal hypothyroidism diminished exogenous NO-mediated diastolic effects in fetal rat thoracic aorta smooth muscle via increased oxidative stress.
LipoxinA(4) analog BML-111 protects podocytes cultured in high-glucose medium against oxidative injury via activating Nrf2 pathway.
Aucubin promoted neuron functional recovery by suppressing inflammation and neuronal apoptosis in a spinal cord injury model.
Tumor-associated macrophages promote migration and invasion via modulating IL-6/STAT3 signaling in renal cell carcinoma.
Chicoric acid attenuates tumor necrosis factor-α-induced inflammation and apoptosis via the Nrf2/HO-1, PI3K/AKT and NF-κB signaling pathways in C28/I2 cells and ameliorates the progression of osteoarthritis in a rat model.
The role of AMPK-Sirt1-autophagy pathway in the intestinal protection process by propofol against regional ischemia/reperfusion injury in rats.
Parthenolide modulates cerebral ischemia-induced microglial polarization and alleviates neuroinflammatory injury via the RhoA/ROCK pathway.
Involvement of Rab11 in osteoblastic differentiation: Its up-regulation during the differentiation and by tensile stress.
Tension of plus-end tracking protein Clip170 confers directionality and aggressiveness during breast cancer migration.
Relationship between the expression of ARHGAP25 and RhoA in non-small cell lung cancer and vasculogenic mimicry.
Bisdemethoxycurcumin Alleviates Dextran Sodium Sulfate-Induced Colitis via Inhibiting NLRP3 Inflammasome Activation and Modulating the Gut Microbiota in Mice.
NCAPG Promotes Pulmonary Artery Smooth Muscle Cell Proliferation as a Promising Therapeutic Target of Idiopathic Pulmonary Hypertension: Bioinformatics Analysis and Experiment Verification.
Stratifin as a novel diagnostic biomarker in serum for diffuse alveolar damage.
Succinate communicates pro-inflammatory signals to the host and regulates bile acid enterohepatic metabolism in a pig model.
Circular RNA circBNC2 inhibits epithelial cell G2-M arrest to prevent fibrotic maladaptive repair.
RNA-seq transcriptome profiling of liver regeneration in mice identifies the miR-34b-5p/phosphoinositide-dependent protein kinase 1 axis as a potential target for hepatocyte proliferation.
Sinensetin attenuates IL-1β-induced cartilage damage and ameliorates osteoarthritis by regulating SERPINA3.
Naringenin activates beige adipocyte browning in high fat diet-fed C57BL/6 mice by shaping the gut microbiota.
Lipid-lowering activity of metformin-soluble soybean polysaccharide nanoparticles.
The Translational Landscape Revealed the Sequential Treatment Containing ATRA plus PI3K/AKT Inhibitors as an Efficient Strategy for AML Therapy.
Paclitaxel Induces the Apoptosis of Prostate Cancer Cells via ROS-Mediated HIF-1α Expression.
Cytomegalovirus-specific neutralizing antibodies effectively prevent uncontrolled infection after allogeneic hematopoietic stem cell transplantation.
NUPR1 contributes to radiation resistance by maintaining ROS homeostasis via AhR/CYP signal axis in hepatocellular carcinoma.
Tumor microenvironment-related gene selenium-binding protein 1 (SELENBP1) is associated with immunotherapy efficacy and survival in colorectal cancer.
Cellular PSMB4 Protein Suppresses Influenza A Virus Replication through Targeting NS1 Protein.
7-Methoxyisoflavone suppresses vascular endothelial inflammation by inhibiting the expression of endothelial adhesion molecules.
Hypoxia-inducible Factor Regulates Ten-eleven Translocated Methylcytosine Dioxygenase 1-c-Myc Binding Involved in Depression-like Behavior in Prenatal Hypoxia Offspring.
MicroRNA-122a aggravates intestinal ischemia/reperfusion injury by promoting pyroptosis via targeting EGFR-NLRP3 signaling pathway.
Embryonic Deletion of TXNIP in GABAergic Neurons Enhanced Oxidative Stress in PV+ Interneurons in Primary Somatosensory Cortex of Aging Mice: Relevance to Schizophrenia.
Osteoclast-Driven Osteogenesis, Bone Remodeling and Biomaterial Resorption: A New Profile of BMP2-CPC-Induced Alveolar Bone Regeneration.
Immunity of two novel hepatitis C virus polyepitope vaccines.
The Effect of Circumscribed Exposure to the Pan-Aurora Kinase Inhibitor VX-680 on Proliferating Euploid Cells.
Loss of BAF (mSWI/SNF) chromatin-remodeling ATPase Brg1 causes multiple malformations of cortical development in mice.
Melanoma stem cells promote metastasis via exosomal miR-1268a inactivation of autophagy.
Geniposide attenuates spermatogenic dysfunction via inhibiting endoplasmic reticulum stress in male mice.
The Role and Mechanism of CREBH Regulating SIRT3 in Metabolic Associated Fatty Liver Disease.
Promotion of tumor progression induced by continuous low-dose administration of antineoplastic agent gemcitabine or gemcitabine combined with cisplatin.
Role of non-neuronal cholinergic system in the early stage response of epithelial-mesenchymal transformation related markers in A549 cells induced by coal particles.
RNF2 mediates pulmonary fibroblasts activation and proliferation by regulating mTOR and p16-CDK4-Rb1 signaling pathway.
Selenoprotein K contributes to CD36 subcellular trafficking in hepatocytes by accelerating nascent COPII vesicle formation and aggravates hepatic steatosis.
Gomisin A enhances the antitumor effect of paclitaxel by suppressing oxidative stress in ovarian cancer.
Basolateral Amygdala Reactive Microglia May Contribute to Synaptic Impairment and Depressive-Like Behavior in Mice with Bone Cancer Pain.
An oleanolic acid derivative, K73-03, inhibits pancreatic cancer cells proliferation in vitro and in vivo via blocking EGFR/Akt pathway.
Acyl-CoA thioesterase 9 promotes tumour growth and metastasis through reprogramming of fatty acid metabolism in hepatocellular carcinoma.
Roles of C/EBP-homologous protein and histone H3 lysine 4 methylation in arsenic-induced mitochondrial apoptosis in hepatocytes.
OL-FS13 alleviates experimental cerebral ischemia-reperfusion injury.
S100A8 regulates autophagy-dependent ferroptosis in microglia after experimental subarachnoid hemorrhage.
A Novel Mouse Model of Idiopathic Nephrotic Syndrome Induced by Immunization with the Podocyte Protein Crb2.
Channel HCN4 mutation R666Q associated with sporadic arrhythmia decreases channel electrophysiological function and increases protein degradation.
A critical ETV4/Twist1/Vimentin axis in Ha-RAS-induced aggressive breast cancer.
A novel synthetic chalcone derivative, 2,4,6-trimethoxy-4'-nitrochalcone (Ch-19), exerted anti-tumor effects through stimulating ROS accumulation and inducing apoptosis in esophageal cancer cells.
Phosphorylation-mediated PI3K-Art signalling pathway as a therapeutic mechanism in the hydrogen-induced alleviation of brain injury in septic mice.
Genistein Alleviates Oxidative Stress and Inflammation in the Hypothalamic Paraventricular Nucleus by Activating the Sirt1/Nrf2 Pathway in High Salt-Induced Hypertension.
Effect of Astragalus polysaccharides on the cryopreservation of goat semen.
Ellagic Acid Alleviates Mice Intestinal Ischemia-Reperfusion Injury: A Study Based on Transcriptomics Combined with Functional Experiments.
Cognitive-exercise dual-task intervention ameliorates cognitive decline in natural aging rats through reducing oxidative stress and enhancing synaptic plasticity.
Mettl3 regulates hypertrophic differentiation of chondrocytes through modulating Dmp1 mRNA via Ythdf1-mediated m(6)A modification.
Acetyl-Coenzyme A Synthetase 2 Potentiates Macropinocytosis and Muscle Wasting Through Metabolic Reprogramming in Pancreatic Cancer.
Tnfaip2 promotes atherogenesis by enhancing oxidative stress induced inflammation.
Transglutaminase 3 Attenuates Skin Inflammation in Psoriasis by Inhibiting NF-κB Activation through Phosphorylated STAT3-TET3 Signaling.
Functional analyses of two interferon-stimulated gene 15 (ISG15) copies in large yellow croaker, Larimichthys crocea.
Diterpenoids from the whole plant of Euphorbia wallichii and their protective effects on H(2)O(2)-induced BV-2 microglial cells injury.
Capsaicin suppresses hepatocarcinogenesis by inhibiting the stemness of hepatic progenitor cells via SIRT1/SOX2 signaling pathway.
Pectin supplementation ameliorates intestinal epithelial barrier function damage by modulating intestinal microbiota in lipopolysaccharide-challenged piglets.
Myo1b promotes tumor progression and angiogenesis by inhibiting autophagic degradation of HIF-1α in colorectal cancer.
A dynamic fluorescence probed glycolysis suppression process in HeLa cells treated with trichostatin A.
Kruppel-like factor 13 inhibits cell proliferation of gastric cancer by inducing autophagic degradation of β-catenin.
Placenta-Targeted Nanoparticles Loaded with PFKFB3 Overexpression Plasmids Enhance Angiogenesis and Placental Function.
Trichostatin D as a Novel KLF2 Activator Attenuates TNFα-Induced Endothelial Inflammation.
Carbon dots derived from folic acid attenuates osteoarthritis by protecting chondrocytes through NF-κB/MAPK pathway and reprogramming macrophages.
Identification of circular RNA BTBD7_hsa_circ_0000563 as a novel biomarker for coronary artery disease and the functional discovery of BTBD7_hsa_circ_0000563 based on peripheral blood mononuclear cells: a case control study.
GRP75 Modulates Endoplasmic Reticulum-Mitochondria Coupling and Accelerates Ca(2+)-Dependent Endothelial Cell Apoptosis in Diabetic Retinopathy.
A Class I HDAC Inhibitor BG45 Alleviates Cognitive Impairment through the CaMKII/ITPKA/Ca(2+) Signaling Pathway.
MiR-145 inhibits the differentiation and proliferation of bone marrow stromal mesenchymal stem cells by GABARAPL1 in steroid-induced femoral head necrosis.
A Novel High-Throughput Screening Method for a Human Multicentric Osteosarcoma-Specific Antibody and Biomarker Using a Phage Display-Derived Monoclonal Antibody.
The Aurora Kinase Inhibitor TAK901 Inhibits Glioblastoma Growth by Blocking SREBP1-Mediated Lipid Metabolism.
Suffruticosol C-Mediated Autophagy and Cell Cycle Arrest via Inhibition of mTORC1 Signaling.
Transmissible Gastroenteritis Virus Nucleocapsid Protein Interacts with Na(+)/H(+) Exchanger 3 To Reduce Na(+)/H(+) Exchanger Activity and Promote Piglet Diarrhea.
PSMA1 mediates tumor progression and poor prognosis of gastric carcinoma by deubiquitinating and stabilizing TAZ.
JMJD1C Regulates Megakaryopoiesis in In Vitro Models through the Actin Network.
mTOR inhibition attenuates chemosensitivity through the induction of chemotherapy resistant persisters.
Autophagy Mediates Escherichia Coli-Induced Cellular Inflammatory Injury by Regulating Calcium Mobilization, Mitochondrial Dysfunction, and Endoplasmic Reticulum Stress.
NNMT-DNMT1 Axis is Essential for Maintaining Cancer Cell Sensitivity to Oxidative Phosphorylation Inhibition.
Inhibition of human peptide deformylase by actinonin sensitizes glioblastoma cells to temozolomide chemotherapy.
Pu-erh tea increases the metabolite Cinnabarinic acid to improve circadian rhythm disorder-induced obesity.
Qingfei oral liquid alleviates RSV-induced lung inflammation by promoting fatty-acid-dependent M1/M2 macrophage polarization via the Akt signaling pathway.
A multi-target directed ligands strategy for the treatment of Alzheimer's disease: Dimethyl fumarate plus Tranilast modified Dithiocarbate as AChE inhibitor and Nrf2 activator.
Salecan ameliorates liver injury by regulating gut microbiota and its metabolites.
Targeting glutamine metabolism in hepatic stellate cells alleviates liver fibrosis.
Protective Effect of Flavonoids against Methylglyoxal-Induced Oxidative Stress in PC-12 Neuroblastoma Cells and Its Structure-Activity Relationships.
Circular RNA hsa_circ_0051040 Promotes Hepatocellular Carcinoma Progression by Sponging miR-569 and Regulating ITGAV Expression.
Rhodiola activates macrophage migration inhibitory factor to alleviate non-alcoholic fatty liver disease.
Molecular and functional characterization of teleost-specific Interleukin-17N in yellow catfish (Pelteobagrus fulvidraco).
Altered Liver Metabolism, Mitochondrial Function, Oxidative Status, and Inflammatory Response in Intrauterine Growth Restriction Piglets with Different Growth Patterns before Weaning.
Silibinin improves L-cell mass and function through an estrogen receptor-mediated antioxidative mechanism.
Unveiling the anti-senescence effects and senescence-associated secretory phenotype (SASP) inhibitory mechanisms of Scutellaria baicalensis Georgi in low glucose-induced astrocytes based on boolean network.
Jumonji-C domain-containing protein 5 suppresses proliferation and aerobic glycolysis in pancreatic cancer cells in a c-Myc-dependent manner.
Astrocytic p75(NTR) expression provoked by ischemic stroke exacerbates the blood-brain barrier disruption.
Macamide B Pretreatment Attenuates Neonatal Hypoxic-Ischemic Brain Damage of Mice Induced Apoptosis and Regulates Autophagy via the PI3K/AKT Signaling Pathway.
Candida albicans induces upregulation of programmed death ligand 1 in oral squamous cell carcinoma.
Transcriptome Profiling Analysis Identifies LCP1 as a Contributor for Chidamide Resistance in Gastric Cancer.
Nrf2 improves hippocampal synaptic plasticity, learning and memory through the circ-Vps41/miR-26a-5p/CaMKIV regulatory network.
Minocycline Pretreatment Prevents Blood-Brain Barrier Disruption in Septic Rats.
Venetoclax enhances DNA damage induced by XPO1 inhibitors: A novel mechanism underlying the synergistic antileukaemic effect in acute myeloid leukaemia.
NEDD4 attenuates phosgene-induced acute lung injury through the inhibition of Notch1 activation.
Calpain-1 mediates vascular remodelling and fibrosis via HIF-1α in hypoxia-induced pulmonary hypertension.
ANKRD37 inhibits trophoblast migration and invasion by regulating the NF-κB pathway in preeclampsia.
Long noncoding RNA GAS5 inhibits proliferation and metastasis in papillary thyroid carcinoma through the IFN/STAT1 signaling pathway.
MicroRNA-20a promotes non-small cell lung cancer proliferation by upregulating PD-L1 by targeting PTEN.
PM(2.5) induced lung injury through upregulating ROS-dependent NLRP3 Inflammasome-Mediated Pyroptosis.
Zinc Alleviates Arsenic-Induced Inflammation and Apoptosis in the Head Kidney of Common Carp by Inhibiting Oxidative Stress and Endoplasmic Reticulum Stress.
Sodium tanshinone IIA sulfonate enhances the BMP9-BMPR2-Smad1/5/9 signaling pathway in rat pulmonary microvascular endothelial cells and human embryonic stem cell-derived endothelial cells.
Ghrelin ameliorates diabetes-associated behavioral deficits and NLRP3 inflammasome activation via autophagic flux enhancement.
Angiotensin-(1-7) improves diabetes mellitus-induced erectile dysfunction in rats by regulating nitric oxide synthase levels.
Mitochondrial transcription factor B2 overexpression increases M2 macrophage infiltration via cytosolic mitochondrial DNA-stimulated Interleukin-6 secretion in ovarian cancer.
A novel hypoxia-driven gene signature that can predict the prognosis of hepatocellular carcinoma.
Circular RNA CircSHKBP1 accelerates the proliferation, invasion, angiogenesis, and stem cell-like properties via modulation of microR-766-5p/high mobility group AT-hook 2 axis in laryngeal squamous cell carcinoma.
Extracellular vesicles rich in HAX1 promote angiogenesis by modulating ITGB6 translation.
SIRT3-AMPK signaling pathway as a protective target in endothelial dysfunction of early sepsis.
HIF-1α inhibition attenuates severity of Achilles tendinopathy by blocking NF-κB and MAPK pathways.
Deletion of MTAP Highly Sensitizes Osteosarcoma Cells to Methionine Restriction With Recombinant Methioninase.
Glucolipotoxicity induces endothelial cell dysfunction by activating autophagy and inhibiting autophagic flow.
A High-Fat Diet Induces Muscle Mitochondrial Dysfunction and Impairs Swimming Capacity in Zebrafish: A New Model of Sarcopenic Obesity.
Hypoxic mesenchymal stem cell-derived extracellular vesicles ameliorate renal fibrosis after ischemia-reperfusion injure by restoring CPT1A mediated fatty acid oxidation.
GLUT5-KHK axis-mediated fructose metabolism drives proliferation and chemotherapy resistance of colorectal cancer.
Therapeutic targeting m6A-guided miR-146a-5p signaling contributes to the melittin-induced selective suppression of bladder cancer.
Resveratrol pretreatment protects neurons from oxygen-glucose deprivation/reoxygenation and ischemic injury through inhibiting ferroptosis.
Impact of Selective Renal Afferent Denervation on Oxidative Stress and Vascular Remodeling in Spontaneously Hypertensive Rats.
Iron-dependent epigenetic modulation promotes pathogenic T cell differentiation in lupus.
Triad3A-Dependent TLR4 Ubiquitination and Degradation Contributes to the Anti-Inflammatory Effects of Pterostilbene on Vascular Dementia.
Characterization of two novel knock-in mouse models of syndromic retinal ciliopathy carrying hypomorphic Sdccag8 mutations.
A novel protein encoded by ZCRB1-induced circHEATR5B suppresses aerobic glycolysis of GBM through phosphorylation of JMJD5.
The underlying rationality of Chinese medicine herb pair Coptis chinensis and Dolomiaea souliei: From the perspective of metabolomics and intestinal function.
Old targets, new strategy: Apigenin-7-O-β-d-(-6″-p-coumaroyl)-glucopyranoside prevents endothelial ferroptosis and alleviates intestinal ischemia-reperfusion injury through HO-1 and MAO-B inhibition.
ATRX-dependent SVCT2 mediates macrophage infiltration in the glioblastoma xenograft model.
Sheng Mai San ameliorated heat stress-induced liver injury via regulating energy metabolism and AMPK/Drp1-dependent autophagy process.
Integrated multi-omics analysis reveals miR-20a as a regulator for metabolic colorectal cancer.
Heat stress-induced mucosal barrier dysfunction is potentially associated with gut microbiota dysbiosis in pigs.
NCAPH regulates gastric cancer progression through DNA damage response.
Ferroptosis promotes microtubule-associated protein tau aggregation via GSK-3β activation and proteasome inhibition.
Cytosine-phosphate-guanine oligodeoxynucleotides regulate the cell cycle, apoptosis, and steroidogenesis of mouse ovarian granulosa cells by targeting inhibin alpha (1 ~ 32) fragments.
Effects of 4-vinylcyclohexene diepoxide on the cell cycle, apoptosis, and steroid hormone secretion of goat ovarian granulosa cells.
NLRP3 Inflammasome Activation Enhances ADK Expression to Accelerate Epilepsy in Mice.
HPV16 E6/E7 stabilize PGK1 protein by reducing its poly-ubiquitination in cervical cancer.
DNA damage-induced translocation of mitochondrial factor HIGD1A into the nucleus regulates homologous recombination and radio/chemo-sensitivity.
O-GlcNAc modification mediates aquaporin 3 to coordinate endometrial cell glycolysis and affects embryo implantation.
A positive feedback circuit comprising p21 and HIF-1α aggravates hypoxia-induced radioresistance of glioblastoma by promoting Glut1/LDHA-mediated glycolysis.
Pseudorabies virus kinase UL13 phosphorylates H2AX to foster viral replication.
Costunolide protects against alcohol-induced liver injury by regulating gut microbiota, oxidative stress and attenuating inflammation in vivo and in vitro.
Injectable hydrogel with nucleus pulposus-matched viscoelastic property prevents intervertebral disc degeneration.
Arsenic exposure via drinking water during pregnancy and lactation induces autism-like behaviors in male offspring mice.
Moxibustion alleviates decreased ovarian reserve in rats by restoring the PI3K/AKT signaling pathway.
HMGB2 causes photoreceptor death via down-regulating Nrf2/HO-1 and up-regulating NF-κB/NLRP3 signaling pathways in light-induced retinal degeneration model.
Alterations in the expression level of visfatin in the lungs of piglets infected with PRRSV and its effect on PRRSV replication.
SiRNA-circFARSA-loaded porous silicon nanomaterials for pancreatic cancer treatment via inhibition of CircFARSA expression.
Improvement of tube formation model of cell: Application for acute hypoxia in in vitro study of angiogenesis.
Injectable multifunctional CMC/HA-DA hydrogel for repairing skin injury.
Shikonin induces apoptosis and autophagy via downregulation of pyrroline-5-carboxylate reductase1 in hepatocellular carcinoma cells.
The protective effects of butorphanol tartrate against homocysteine-induced blood-brain barrier dysfunction.
MYB proto-oncogene like 2 promotes hepatocellular carcinoma growth and glycolysis via binding to the Optic atrophy 3 promoter and activating its expression.
Klotho alleviates NLRP3 inflammasome-mediated neuroinflammation in a temporal lobe epilepsy rat model by activating the Nrf2 signaling pathway.
Downregulation of NCL attenuates tumor formation and growth in HeLa cells by targeting the PI3K/AKT pathway.
Venetoclax enhances NK cell killing sensitivity of AML cells through the NKG2D/NKG2DL activation pathway.
Sphingomyelin-Sequestered Cholesterol Domain Recruits Formin-Binding Protein 17 for Constricting Clathrin-Coated Pits in Influenza Virus Entry.
The effects of angiotensin I-converting enzyme inhibitory peptide VGINYW and the hydrolysate of α-lactalbumin on blood pressure, oxidative stress and gut microbiota of spontaneously hypertensive rats.
Fucoidan protects the pancreas and improves glucose metabolism through inhibiting inflammation and endoplasmic reticulum stress in T2DM rats.
Multifunctional photodynamic/photothermal nano-agents for the treatment of oral leukoplakia.
N-myristoyltransferase-1 deficiency blocks myristoylation of LAMTOR1 and inhibits bladder cancer progression.
Nuciferine Inhibits TMEM16A in Dietary Adjuvant Therapy for Lung Cancer.
Thermosensitive Hydrogel Incorporating Prussian Blue Nanoparticles Promotes Diabetic Wound Healing via ROS Scavenging and Mitochondrial Function Restoration.
Pseudorabies Virus Inhibits Expression of Liver X Receptors to Assist Viral Infection.
Discovery of Potent PROTACs Targeting EGFR Mutants through the Optimization of Covalent EGFR Ligands.
Inhibition of Metastatic Hepatocarcinoma by Combined Chemotherapy with Silencing VEGF/VEGFR2 Genes through a GalNAc-Modified Integrated Therapeutic System.
The "LLQY" Motif on SARS-CoV-2 Spike Protein Affects S Incorporation into Virus Particles.
A Dual Anti-Inflammatory and Anti-Proliferative 3-Styrylchromone Derivative Synergistically Enhances the Anti-Cancer Effects of DNA-Damaging Agents on Colon Cancer Cells by Targeting HMGB1-RAGE-ERK1/2 Signaling.
Progranulin improves neural development via the PI3K/Akt/GSK-3β pathway in the cerebellum of a VPA-induced rat model of ASD.
Dioscin relieves diabetic nephropathy via suppressing oxidative stress and apoptosis, and improving mitochondrial quality and quantity control.
BMP-7 ameliorates partial epithelial-mesenchymal transition by restoring SnoN protein level via Smad1/5 pathway in diabetic kidney disease.
Effects of iron oxide nanoparticles as T(2)-MRI contrast agents on reproductive system in male mice.
p62 Promotes the Mitochondrial Localization of p53 through Its UBA Domain and Participates in Regulating the Sensitivity of Ovarian Cancer Cells to Cisplatin.
lncRNA SNHG26 promoted the growth, metastasis, and cisplatin resistance of tongue squamous cell carcinoma through PGK1/Akt/mTOR signal pathway.
Long noncoding RNA H19 mediates neural stem/progenitor cells proliferation, differentiation and apoptosis through the p53 signaling pathway after ischemic stroke.
Chelerythrine inhibits the progression of glioblastoma by suppressing the TGFB1-ERK1/2/Smad2/3-Snail/ZEB1 signaling pathway.
Fucoidan ameliorates glucose metabolism by the improvement of intestinal barrier and inflammatory damage in type 2 diabetic rats.
DL-3-n-butylphthalide imparts neuroprotection via Nrf2/SIRT3 pathway in a mouse model of vascular dementia.
The Effects and Mechanisms of the Rapamycin-eluting Stent in Urethral Stricture Prevention in Rabbits.
The Novel Competing Endogenous Long Noncoding RNA SM2 Regulates Gonadotropin Secretion in the Hu Sheep Anterior Pituitary by Targeting the Oar-miR-16b/TGF-β/SMAD2 Signaling Pathway.
Delivery of nVEGFi using AAV8 for the treatment of neovascular age-related macular degeneration.
Transplantation of Human Umbilical Cord Mesenchymal Stem Cells-Derived Neural Stem Cells Pretreated with Neuregulin1β Ameliorate Cerebral Ischemic Reperfusion Injury in Rats.
Autophagy and mitochondrial dynamics contribute to the protective effect of diosgenin against 3-MCPD induced kidney injury.
Systematic characterization of the metabolites of defatted walnut powder extract in vivo and screening of the mechanisms against NAFLD by UPLC-Q-Exactive Orbitrap MS combined with network pharmacology.
Panax notoginseng saponins protect PC12 cells against Aβ induced injury via promoting parkin-mediated mitophagy.
Oxidative stress activates Ryr2-Ca(2+) and apoptosis to promote PM(2.5)-induced heart injury of hyperlipidemia mice.
Endothelial Cells Mediated by UCP2 Control the Neurogenic-to-Astrogenic Neural Stem Cells Fate Switch During Brain Development.
LINC01534/miR-135b-5p/PTPRT axis regulates inflammatory response in loosening total hip replacement via modulating NF-κB signaling pathway.
Detection of netrin-1 as a novel biomarker for diagnosis and chemotherapeutic monitoring of lung cancer.
MCTS1 promotes laryngeal squamous cell carcinoma cell growth via enhancing LARP7 stability.
Serine 727 phosphorylation is necessary to induce the STAT3-mediated transcription of LINC00184 in oesophageal squamous cell carcinoma.
Retracted Article: LncRNA KCNQ1OT1 Promotes Apoptosis and Oxidative Stress of Human Lens Epithelial Cells through Epigenetic Regulation of WRN.
Protection of CAPE-pNO(2) Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro.
Identification of HMGCR as the anticancer target of physapubenolide against melanoma cells by in silico target prediction.
Inhibition of Fatty Acid Translocase (FAT/CD36) Palmitoylation Enhances Hepatic Fatty Acid β-Oxidation by Increasing Its Localization to Mitochondria and Interaction with Long-Chain Acyl-CoA Synthetase 1.
LncRNA SENCR overexpression attenuated the proliferation, migration and phenotypic switching of vascular smooth muscle cells in aortic dissection via the miR-206/myocardin axis.
DDX47 promotes cell proliferation and migration in lung adenocarcinoma.
Amelioration of DSS-Induced Acute Colitis in Mice by Recombinant Monomeric Human Interleukin-22.
Gli(ko) BMSC: A potential strategy of treatment for renal fibrosis.
In situ forming and biocompatible hyaluronic acid hydrogel with reactive oxygen species-scavenging activity to improve traumatic brain injury repair by suppressing oxidative stress and neuroinflammation.
Long noncoding RNA lnc-H2AFV-1 promotes cell growth by regulating aberrant m6A RNA modification in head and neck squamous cell carcinoma.
Exosomal circGSE1 promotes immune escape of hepatocellular carcinoma by inducing the expansion of regulatory T cells.
α(1) -Adrenoceptors activate the NLRP3 inflammasome through downregulation of Kir2.1 in cardiac inflammation.
Proteomic and functional analyses of the periodic membrane skeleton in neurons.
Neonatal gene therapy achieves sustained disease rescue of maple syrup urine disease in mice.
Systematic analyses identify the anti-fibrotic role of lncRNA TP53TG1 in IPF.
mascRNA promotes macrophage apoptosis, inhibits osteoclast differentiation and attenuates disease progression in a murine model of arthritis.
Facilitating Mitophagy via Pink1/Parkin2 Signaling Is Essential for the Neuroprotective Effect of β-Caryophyllene against CIR-Induced Neuronal Injury.
EPLINβ Is Involved in the Assembly of Cadherin-catenin Complexes in Osteoblasts and Affects Bone Formation.
Thymoquinone upregulates IL17RD in controlling the growth and metastasis of triple negative breast cancer cells in vitro.
A DNA damage nanoamplifier for the chemotherapy of triple-negative breast cancer via DNA damage induction and repair blocking.
Effect and mechanism of TFEB on pyroptosis in HK-2 cells induced by high glucose.
Design, Synthesis, and Biological Evaluation of N14-Amino Acid-Substituted Tetrandrine Derivatives as Potential Antitumor Agents against Human Colorectal Cancer.
Deciphering the tumor microenvironment cell-infiltrating landscape reveals microenvironment subtypes and therapeutic potentials for nonsquamous NSCLC.
ERK1/2 Signalling Pathway Regulates Tubulin-Binding Cofactor B Expression and Affects Astrocyte Process Formation after Acute Foetal Alcohol Exposure.
Isolation of five different primary cell types from a single sample of human skin.
FUNDC2 promotes liver tumorigenesis by inhibiting MFN1-mediated mitochondrial fusion.
The hsa-miR-214-3p/ATGL axis regulates aberrant lipolysis to promote acute myeloid leukemia progression via PPARα in vitro.
Long non-coding RNA BBOX1-AS1 exacerbates esophageal squamous cell carcinoma development by regulating HOXB7/β-catenin axis.
Inhibition of HIF-1α Attenuates Silica-Induced Pulmonary Fibrosis.
Protective effect of active components of Eucommia ulmoides leaves on gastric ulcers in rats: Involvement of the PI3K/Akt/NF-κB pathway.
Methylation-mediated expression of SPARC is correlated with tumor progression and poor prognosis of breast cancer.
LncRNA BIRF Promotes Brain Ischemic Tolerance Induced By Cerebral Ischemic Preconditioning Through Upregulating GLT-1 via Sponging miR-330-5p.
Circ_0076305 facilitates prostate cancer development via sponging miR-411-5p and regulating PGK1.
MG53 protein rejuvenates hUC-MSCs and facilitates their therapeutic effects in AD mice by activating Nrf2 signaling pathway.
The combination of decitabine and aspirin inhibits tumor growth and metastasis in non-small cell lung cancer.
Long Non-coding RNA ANRIL Downregulation Alleviates Neuroinflammation in an Ischemia Stroke Model via Modulation of the miR-671-5p/NF-κB Pathway.
Rosa centifolia petal extract induces endothelium-dependent and endothelium-independent vasorelaxation in rat aorta and prevents accumulation of inflammatory factors in human umbilical vein endothelial cells.
Gamma-oryzanol protects human liver cell (L02) from hydrogen peroxide-induced oxidative damage through regulation of the MAPK/Nrf2 signaling pathways.
The involvement of TRPM2 on the MPP(+)-induced oxidative neurotoxicity and apoptosis in hippocampal neurons from neonatal mice: protective role of resveratrol.
Downregulation of HINFP induces senescence-associated secretory phenotype to promote metastasis in a non-cell-autonomous manner in bladder cancer.
SPATA33 affects the formation of cell adhesion complex by interacting with CTNNA3 in TM4 cells.
Indole-3-propionic acid alleviates ischemic brain injury in a mouse middle cerebral artery occlusion model.
Mitochondrial and glucose metabolic dysfunctions in granulosa cells induce impaired oocytes of polycystic ovary syndrome through Sirtuin 3.
The BDNF-TrkB signaling pathway in the rostral anterior cingulate cortex is involved in the development of pain aversion in rats with bone cancer via NR2B and ERK-CREB signaling.
A specific EMC subunit supports Dengue virus infection by promoting virus membrane fusion essential for cytosolic genome delivery.
Parkin-mediated mitophagy protects against TNF-α-induced stress in bone marrow mesenchymal stem cells.
Paeoniflorin-6'-o-benzene sulfonate ameliorates the progression of adjuvant-induced arthritis by inhibiting the interaction between Ahr and GRK2 of fibroblast-like synoviocytes.
Acetyl-L-carnitine improves erectile function in bilateral cavernous nerve injury rats via promoting cavernous nerve regeneration.
LGALS3BP in Microglia Promotes Retinal Angiogenesis Through PI3K/AKT Pathway During Hypoxia.
Identification of PDCD2 as a Candidate Target of Andrographolide That Arrests the Tumor Cell Cycle by Human Proteome-Scale Screening.
KDM4C Contributes to Trophoblast-like Stem Cell Conversion from Porcine-Induced Pluripotent Stem Cells (piPSCs) via Regulating CDX2.
Stabilization of SAMHD1 by NONO is crucial for Ara-C resistance in AML.
Mitochondrial fission induces immunoescape in solid tumors through decreasing MHC-I surface expression.
Cyclosporin A up-regulated thromboxane A(2) receptor through activation of MAPK and NF-κB pathways in rat mesenteric artery.
Sestrin2 remedies podocyte injury via orchestrating TSP-1/TGF-β1/Smad3 axis in diabetic kidney disease.
Dysregulation of SIRT3 SUMOylation Confers AML Chemoresistance via Controlling HES1-Dependent Fatty Acid Oxidation.
Severe inflammation in new-borns induces long-term cognitive impairment by activation of IL-1β/KCC2 signaling during early development.
DSF/Cu induces antitumor effect against diffuse large B-cell lymphoma through suppressing NF-κB/BCL6 pathways.
Mitochondria-Targeting Polymer Micelle of Dichloroacetate Induced Pyroptosis to Enhance Osteosarcoma Immunotherapy.
Muscone and (+)-Borneol Cooperatively Strengthen CREB Induction of Claudin 5 in IL-1β-Induced Endothelium Injury.
miR-335-5p regulates the proliferation, migration and phenotypic switching of vascular smooth muscle cells in aortic dissection by directly regulating SP1.
Nintedanib Inhibits Endothelial Mesenchymal Transition in Bleomycin-Induced Pulmonary Fibrosis via Focal Adhesion Kinase Activity Reduction.
The BDNF-TrkB-CREB Signalling Pathway Is Involved in Bisphenol S-Induced Neurotoxicity in Male Mice by Regulating Methylation.
CTNND1 variants cause familial exudative vitreoretinopathy through the Wnt/cadherin axis.
Ventilator-induced lung injury results in oxidative stress response and mitochondrial swelling in a mouse model.
Mitotic SENP3 activation couples with cGAS signaling in tumor cells to stimulate anti-tumor immunity.
Salidroside Ameliorates Radiation Damage by Reducing Mitochondrial Oxidative Stress in the Submandibular Gland.
Ssc-MiR-21-5p and Ssc-MiR-615 Regulates the Proliferation and Apoptosis of Leydig Cells by Targeting SOX5.
Self-Assembly of a Multifunction DNA Tetrahedron for Effective Delivery of Aptamer PL1 and Pcsk9 siRNA Potentiate Immune Checkpoint Therapy for Colorectal Cancer.
Spiropachysine A suppresses hepatocellular carcinoma proliferation by inducing methuosis in vitro and in vivo.
P2X7R/NLRP3 signaling pathway-mediated pyroptosis and neuroinflammation contributed to cognitive impairment in a mouse model of migraine.
Self-construction of actin networks through phase separation-induced abLIM1 condensates.
TTK Protein Kinase promotes temozolomide resistance through inducing autophagy in glioblastoma.
High glucose and palmitic acid induces neuronal senescence by NRSF/REST elevation and the subsequent mTOR-related autophagy suppression.
Chitosan Oligosaccharide Attenuates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction through Suppressing the Inflammatory Response and Oxidative Stress in Mice.
Protective role of small extracellular vesicles derived from HUVECs treated with AGEs in diabetic vascular calcification.
Adrenomedullin is an Important Pathological Mediator in Progression of Chronic Neuropathic Pain.
Bile Duct Ligation Impairs Function and Expression of Mrp1 at Rat Blood-Retinal Barrier via Bilirubin-Induced P38 MAPK Pathway Activations.
Mitochondrial PKM2 deacetylation by procyanidin B2-induced SIRT3 upregulation alleviates lung ischemia/reperfusion injury.
TFRC upregulation promotes ferroptosis in CVB3 infection via nucleus recruitment of Sp1.
Effects of bamboo leaf extract intervention on the growth performance, antioxidant capacity, and hepatic apoptosis in suckling piglets.
A novel regulatory mechanism of geniposide for improving glucose homeostasis mediated by circulating RBP4.
Protocatechuic aldehyde prevents ischemic injury by attenuating brain microvascular endothelial cell pyroptosis via lncRNA Xist.
Hydrogen sulphide attenuates neuronal apoptosis of substantia nigra by re-establishing autophagic flux via promoting leptin signalling in a 6-hydroxydopamine rat model of Parkinson's disease.
Dihydroartemisinin attenuates osteoclast formation and bone resorption via inhibiting the NF‑κB, MAPK and NFATc1 signaling pathways and alleviates osteoarthritis.
DR1 activation promotes vascular smooth muscle cell apoptosis via up-regulation of CSE/H(2) S pathway in diabetic mice.
Corilagin induces apoptosis and inhibits autophagy of HL‑60 cells by regulating miR‑451/HMGB1 axis.
Identification of a novel native peptide derived from 60S ribosomal protein L23a that translationally regulates p53 to reduce myocardial ischemia-reperfusion.
Jujuboside A ameliorates high fat diet and streptozotocin induced diabetic nephropathy via suppressing oxidative stress, apoptosis, and enhancing autophagy.
Adaptation to partial urethral obstruction in healthy aging LOU rats and the role of nerve growth factor signaling pathway in the bladder.
Overexpression of sFlt-1 represses ox-LDL-induced injury of HUVECs by activating autophagy via PI3K/AKT/mTOR pathway.
Dihydroartemisinin represses oral squamous cell carcinoma progression through downregulating mitochondrial calcium uniporter.
Drp1 knockdown represses apoptosis of rat retinal endothelial cells by inhibiting mitophagy.
Inhibition of CDK1 attenuates neuronal apoptosis and autophagy and confers neuroprotection after chronic spinal cord injury in vivo.
An in vitro senescence model of gingival epithelial cell induced by hydrogen peroxide treatment.
Inhibition of the proliferation, invasion, migration, and epithelial-mesenchymal transition of prostate cancer cells through the action of ATP1A2 on the TGF-β/Smad pathway.
Antitumor and Antibacterial Efficacy of Gallium Nanoparticles Coated by Ellagic Acid.
Molecular imaging and treatment of PSMA-positive prostate cancer with (99m)Tc radiolabeled aptamer-siRNA chimeras.
Gestational bisphenol A exposure impairs hepatic lipid metabolism by altering mTOR/CRTC2/SREBP1 in male rat offspring.
Effects of butein on human osteosarcoma cell proliferation, apoptosis, and autophagy through oxidative stress.
Evodiamine suppresses the progression of non-small cell lung carcinoma via endoplasmic reticulum stress-mediated apoptosis pathway in vivo and in vitro.
Effects of Low-Intensity Pulsed Ultrasound on the Migration and Homing of Human Amnion-Derived Mesenchymal Stem Cells to Ovaries in Rats With Premature Ovarian Insufficiency.
The role of regulatory T cells on the activation of astrocytes in the brain of high-fat diet mice following lead exposure.
Circular RNA circCCDC85A inhibits breast cancer progression via acting as a miR-550a-5p sponge to enhance MOB1A expression.
Ceria nanoparticles ameliorate renal fibrosis by modulating the balance between oxidative phosphorylation and aerobic glycolysis.
Increased expression of osteopontin in subchondral bone promotes bone turnover and remodeling, and accelerates the progression of OA in a mouse model.
A comprehensive analysis of age-related metabolomics and transcriptomics reveals metabolic alterations in rat bone marrow mesenchymal stem cells.
Leptin relieves ischemia/reperfusion induced acute kidney injury through inhibiting apoptosis and autophagy.
NAD(P)H: quinone oxidoreductase 1 attenuates oxidative stress and apoptosis by regulating Sirt1 in diabetic nephropathy.
Mitigation Effects of Selenium Nanoparticles on Depression-Like Behavior Induced by Fluoride in Mice via the JAK2-STAT3 Pathway.
Structural Variability of Lipoarabinomannan Modulates Innate Immune Responses within Infected Alveolar Epithelial Cells.
FSH inhibits autophagy and lysosomal biogenesis to regulate protein degradation in cultured goat Sertoli cells.
In vitro and in silico anti-osteoporosis activities and underlying mechanisms of a fructan, ABW90-1, from Achyranthes bidentate.
Exosomal circRELL1 serves as a miR-637 sponge to modulate gastric cancer progression via regulating autophagy activation.
Phosphorylation-Induced Ubiquitination and Degradation of PXR through CDK2-TRIM21 Axis.
Xiaoyao powder improves endometrial receptivity via VEGFR-2-mediated angiogenesis through the activation of the JNK and P38 signaling pathways.
(125)I seeds inhibit proliferation and promote apoptosis in cholangiocarcinoma cells by regulating the AGR2-mediated p38 MAPK pathway.
Eurycomanol alleviates hyperuricemia by promoting uric acid excretion and reducing purine synthesis.
Isoliquiritigenin-mediated miR-23a-3p inhibition activates PGC-1α to alleviate alcoholic liver injury.
Activation of the NLRP3 inflammasome by RAC1 mediates a new mechanism in diabetic nephropathy.
Single Treatment of Vitamin D3 Ameliorates LPS-Induced Acute Lung Injury through Changing Lung Rodentibacter abundance.
Mesenchymal-to-epithelial transition of osteoblasts induced by Fam20c knockout.
Hydrogen sulfide alleviates apoptosis and autophagy induced by beryllium sulfate in 16HBE cells.
1H-NMR-based metabolomics reveals the biomarker panel and molecular mechanism of hepatocellular carcinoma progression.
Inhibition of MAT2A suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss.
STING-mediated inflammation contributes to Gao binge ethanol feeding model.
Cardiotoxicity of patulin was found in H9c2 cells.
HMGB1 downregulation in retinal pigment epithelial cells protects against diabetic retinopathy through the autophagy-lysosome pathway.
Activation of RIPK2-mediated NOD1 signaling promotes proliferation and invasion of ovarian cancer cells via NF-κB pathway.
Prunella vulgaris can improve the pregnancy outcomes of experimental autoimmune thyroiditis rats by inhibiting Th1/Th17 immune responses.
Enhancement of anti-inflammatory effect of cattle bile by fermentation and its inhibition of neuroinflammation on microglia by inhibiting NLRP3 inflammasome.
Polygonum cuspidatum inhibits the growth of osteosarcoma cells via impeding Akt/ERK/EGFR signaling pathways.
Hyperglycemia induces miR-26-5p down-regulation to overexpress PFKFB3 and accelerate epithelial-mesenchymal transition in gastric cancer.
Dye-Sensitized Rare Earth Nanoparticles with Up/Down Conversion Luminescence for On-Demand Gas Therapy of Glioblastoma Guided by NIR-II Fluorescence Imaging.
The synergistic anticancer effect of the bromodomain inhibitor OTX015 and histone deacetylase 6 inhibitor WT-161 in osteosarcoma.
The human FOXM1 homolog promotes basal progenitor cell proliferation and cortical folding in mouse.
Developing a Mathematical Model of Intracellular Calcium Dynamics for Evaluating Combined Anticancer Effects of Afatinib and RP4010 in Esophageal Cancer.
HDAC9 Contributes to Serous Ovarian Cancer Progression through Regulating Epithelial-Mesenchymal Transition.
The anti-MDR efficacy of YAN against A549/Taxol cells is associated with its inhibition on glycolysis and is further enhanced by 2-deoxy-d-glucose.
Carrier-free multifunctional nanomedicine for intraperitoneal disseminated ovarian cancer therapy.
Ginkgo biloba leaf extract mitigates cisplatin-induced chronic renal interstitial fibrosis by inhibiting the epithelial-mesenchymal transition of renal tubular epithelial cells mediated by the Smad3/TGF-β1 and Smad3/p38 MAPK pathways.
Transketolase promotes colorectal cancer metastasis through regulating AKT phosphorylation.
Mitochondrial homeostasis regulates definitive endoderm differentiation of human pluripotent stem cells.
Preparation, Characterization, Evaluation of Neuroprotective Effect, and Related Mechanisms of Phosphatidylserine Emulsion in 5- and 12-Week Old Mice.
Isovitexin protects against acute liver injury by targeting PTEN, PI3K and BiP via modification of m6A.
TiO(2) nanosheets promote the transformation of vascular smooth muscle cells into foam cells in vitro and in vivo through the up-regulation of nuclear factor kappa B subunit 2.
Blockage of citrate export prevents TCA cycle fragmentation via Irg1 inactivation.
Liver fibrosis alters the molecular structures of hepatic glycogen.
The expression of m6A enzymes in the hippocampus of diabetic cognitive impairment mice and the possible improvement of YTHDF1.
African Swine Fever Virus K205R Induces ER Stress and Consequently Activates Autophagy and the NF-κB Signaling Pathway.
Ergosterol Peroxide Inhibits Porcine Epidemic Diarrhea Virus Infection in Vero Cells by Suppressing ROS Generation and p53 Activation.
Genetic Deletion of HLJ1 Does Not Affect Blood Coagulation in Mice.
Intake of flavonoids from Astragalus membranaceus ameliorated brain impairment in diabetic mice via modulating brain-gut axis.
Sestrin2 reduces cancer stemness via Wnt/β-catenin signaling in colorectal cancer.
Pt(II)-NHC Complex Induces ROS-ERS-Related DAMP Balance to Harness Immunogenic Cell Death in Hepatocellular Carcinoma.
Exploring the pharmacological mechanism of calculus bovis in cerebral ischaemic stroke using a network pharmacology approach.
Immobilization of peroxisome proliferator-activated receptor gamma and the application in screening modulators of the receptor from herbal medicine.
Effects of STAT3 Inhibitor BP-1-102 on The Proliferation, Invasiveness, Apoptosis and Neurosphere Formation of Glioma Cells in Vitro.
Cystine Induced-mTORC2 Activation through Promoting Sin1 Phosphorylation to Suppress Cancer Cell Ferroptosis.
A plant-derived natural photosynthetic system for improving cell anabolism.
Cinobufagin induces acute promyelocytic leukaemia cell apoptosis and PML-RARA degradation in a caspase-dependent manner by inhibiting the β-catenin signalling pathway.
Antidepressant effects of total alkaloids of Fibraurea recisa on improving corticosterone-induced apoptosis of HT-22 cells and chronic unpredictable mild stress-induced depressive-like behaviour in mice.
ChemR23 signaling ameliorates cognitive impairments in diabetic mice via dampening oxidative stress and NLRP3 inflammasome activation.
Taurine protects R28 cells from hypoxia/re-oxygenation-induced damage via regulation of mitochondrial energy metabolism.
Holothuria Leucospilota polysaccharides alleviate hyperlipidemia via alteration of lipid metabolism and inflammation-related gene expression.
Resveratrol inhibits the progression of premature senescence partially by regulating v-rel avian reticuloendotheliosis viral oncogene homolog A (RELA) and sirtuin 1 (SIRT1).
Salidroside inhibited cerebral ischemia/reperfusion-induced oxidative stress and apoptosis via Nrf2/Trx1 signaling pathway.
Loureirin C ameliorates ischemia and reperfusion injury in rats by inhibiting the activation of the TLR4/NF-κB pathway and promoting TLR4 degradation.
A comprehensive analysis on the relationship between BDE-209 exposure and erectile dysfunction.
CEND1 deficiency induces mitochondrial dysfunction and cognitive impairment in Alzheimer's disease.
Anti-photoaging effects of flexible nanoliposomes encapsulated Moringa oleifera Lam. isothiocyanate in UVB-induced cell damage in HaCaT cells.
Sevelamer arsenite nanoparticle as a Pi-responsive drug carrier and embolic agent for chemoembolization.
Hypoxia-Inducible Factor 1α Stability Modified by Glutaredoxin-1 in Necrotizing Enterocolitis.
Mild hypothermia ameliorates hepatic ischemia reperfusion injury by inducing RBM3 expression.
Orientin downregulating oxidative stress-mediated endoplasmic reticulum stress and mitochondrial dysfunction through AMPK/SIRT1 pathway in rat nucleus pulposus cells in vitro and attenuated intervertebral disc degeneration in vivo.
Tetrandrine overcomes drug resistance mediated by bone marrow microenvironment by regulating the expression of P-glycoprotein in acute leukemia.
SREBP2/Rab11s/GLUT1/6 network regulates proliferation and migration of glioblastoma.
Global Phosphoproteomics Unveils Kinase-Regulated Networks in Systemic Lupus Erythematosus.
Study on the mechanism of scutellarin's protective effect against ZEA-induced mouse ovarian granulosa cells injury.
Enhancement of the functionality of attenuating acute lung injury by a microemulsion formulation with volatile oil of Angelicae Sinensis Radix and Ligusticum Chuanxiong Rhizoma encapsulated.
Hyperoside protects against cyclophosphamide induced ovarian damage and reduced fertility by suppressing HIF-1α/BNIP3-mediated autophagy.
miR-141-3p affects β-catenin signaling and apoptosis by targeting Ubtd2 in rats with anorectal malformations.
Bioelectric fields coordinate wound contraction and re-epithelialization process to accelerate wound healing via promoting myofibroblast transformation.
1,25(OH)(2)D(3) alleviates LPS-induced preeclampsia-like rats impairment in the protective effect by TLR4/NF-kB pathway.
Activation of RKIP Binding ASC Attenuates Neuronal Pyroptosis and Brain Injury via Caspase-1/GSDMD Signaling Pathway After Intracerebral Hemorrhage in Mice.
Inhibition of glutamine transporter ASCT2 mitigates bleomycin-induced pulmonary fibrosis in mice.
MCPIP1 alleviates inflammatory response through inducing autophagy in Aspergillus fumigatus keratitis.
A mouse-adapted CVA6 strain exhibits neurotropism and triggers systemic manifestations in a novel murine model.
Probiotic-fermented Pueraria lobata (Willd.) Ohwi alleviates alcoholic liver injury by enhancing antioxidant defense and modulating gut microbiota.
GALNT3 protects against phosphate-induced calcification in vascular smooth muscle cells by enhancing active FGF23 and inhibiting the wnt/β-catenin signaling pathway.
MicroRNA-200c Affects Milk Fat Synthesis by Targeting PANK3 in Ovine Mammary Epithelial Cells.
A Recombinant Genotype I Japanese Encephalitis Virus Expressing a Gaussia Luciferase Gene for Antiviral Drug Screening Assay and Neutralizing Antibodies Detection.
Cordycepin exhibits anti-fatigue effect via activating TIGAR/SIRT1/PGC-1α signaling pathway.
FLI1 accelerates leukemogenesis through transcriptional regulation of pyruvate kinase-L/R and other glycolytic genes.
TOP2A deficiency leads to human recurrent spontaneous abortion and growth retardation of mouse pre-implantation embryos.
FNDC5 Promotes Adipogenic Differentiation of Primary Preadipocytes in Mashen Pigs.
Circadian Rhythm Disorders Aggravate Periodontitis by Modulating BMAL1.
Renoprotective effects of oleanolic acid and its possible mechanisms in rats with diabetic kidney disease.
Cefotetan-bound human RKIP involves in Ras/Raf1/MEK/ERK signaling pathway.
Low Sulfur Amino Acid, High Polyunsaturated Fatty Acid Diet Inhibits Breast Cancer Growth.
ADAR1p110 promotes Enterovirus D68 replication through its deaminase domain and inhibition of PKR pathway.
Glucagon-like Peptide 1 Receptor Activation Inhibits Microglial Pyroptosis via Promoting Mitophagy to Alleviate Depression-like Behaviors in Diabetic Mice.
Transcriptome and Gut Microbiota Profiling Analysis of ANIT-Induced Cholestasis and the Effects of Da-Huang-Xiao-Shi Decoction Intervention.
SRA Suppresses Antiviral Innate Immune Response in Macrophages by Limiting TBK1 K63 Ubiquitination via Deubiquitinase USP15.
Beta-naphthoflavone and doxorubicin synergistically enhance apoptosis in human lung cancer cells by inducing doxorubicin accumulation, mitochondrial ROS generation, and JNK pathway signaling.
RNA-m6A modification of HDGF mediated by Mettl3 aggravates the progression of atherosclerosis by regulating macrophages polarization via energy metabolism reprogramming.
ABHD16A Negatively Regulates the Palmitoylation and Antiviral Function of IFITM Proteins.
Dihydrotanshinone I Inhibits the Lung Metastasis of Breast Cancer by Suppressing Neutrophil Extracellular Traps Formation.
Epigenetic silencing of JAM3 promotes esophageal cancer development by activating Wnt signaling.
Titania-Nanotube-Coated Titanium Substrates Promote Osteogenesis and Suppress Osteoclastogenesis via Integrin ανβ3.
Thrombus Inhibition and Neuroprotection for Ischemic Stroke Treatment through Platelet Regulation and ROS Scavenging.
The Photoperiod Regulates Granulosa Cell Apoptosis through the FSH-Nodal/ALK7 Signaling Pathway in Phodopus sungorus.
Verteporfin inhibits the dedifferentiation of tubular epithelial cells via TGF-β1/Smad pathway but induces podocyte loss in diabetic nephropathy.
An electrochemical nitric oxide generator for in-home inhalation therapy in pulmonary artery hypertension.
Histone Deacetylase Inhibitor Panobinostat Benefits the Therapeutic Efficacy of Oncolytic Herpes Simplex Virus Combined with PD-1/PD-L1 Blocking in Glioma and Squamous Cell Carcinoma Models.
Tetrahydroxy Stilbene Glucoside Alleviates Ischemic Stroke by Regulating Conformation-Dependent Intracellular Distribution of PKM2 for M2 Macrophage Polarization.
Nanosilica-Anchored Polycaprolactone/Chitosan Nanofibrous Bioscaffold to Boost Osteogenesis for Bone Tissue Engineering.
The protective effects of sulforaphane on high-fat diet-induced metabolic associated fatty liver disease in mice via mediating the FXR/LXRα pathway.
FOXA1 is a transcriptional activator of Odf2/Cenexin and regulates primary ciliation.
Menadione Potentiates Auranofin-Induced Glioblastoma Cell Death.
The Role of Apoptosis and Autophagy in the Hypothalamic-Pituitary-Adrenal (HPA) Axis after Traumatic Brain Injury (TBI).
Novel bioactive hybrid Celecoxib-HDAC Inhibitor, induces apoptosis in human acute lymphoblastic leukemia cells.
Intracameral Injection of AAV-DJ.COMP-ANG1 Reduces the IOP of Mice by Reshaping the Trabecular Outflow Pathway.
Exposure to melamine cyanuric acid in adult mice caused motor activity and skeletal muscle energy metabolism disorder.
Identification of endocrine-disrupting chemicals targeting the genes and pathways of genital anomalies in males.
Host-induced gene silencing of PcCesA3 and PcOSBP1 confers resistance to Phytophthora capsici in Nicotiana benthamiana through NbDCL3 and NbDCL4 processed small interfering RNAs.
Role of the cGAS-STING Pathway in Aging-related Endothelial Dysfunction.
Effects of the probiotic, Lactobacillus rhamnosus GG, on ulcer pathogenesis, HSP70 stress protein and nitric oxide levels in stress induced ulcer.
Ubiquitin-specific protease 47 regulates intestinal inflammation through deubiquitination of TRAF6 in epithelial cells.
Brown-fat-mediated tumour suppression by cold-altered global metabolism.
Circular RNA expression profile of H(2)O(2) induced ferroptosis model of human coronary artery endothelial cells.
Corn oligopeptides inhibit Akt/NF-κB signaling pathway and inflammatory factors to ameliorate CCl(4) -induced hepatic fibrosis in mice.
Lupeol triggers oxidative stress, ferroptosis, apoptosis and restrains inflammation in nasopharyngeal carcinoma via AMPK/NF-κB pathway.
Protective role of selenium on MPP(+) and homocysteine-induced TRPM2 channel activation in SH-SY5Y cells.
Sodium selenite attenuates zearalenone-induced apoptosis through inhibition of endoplasmic reticulum stress in goat trophoblast cells.
XIST sponges miR-320d to promote chordoma progression by regulating ARF6.
Hsa_circ_0008234 facilitates proliferation of cutaneous squamous cell carcinoma through targeting miR-127-5p to regulate ADCY7.
Silencing of Rab23 by siRNA inhibits ultraviolet B-induced melanogenesis via downregulation of PKA/CREB/MITF.
Iron oxide nanoparticles oxidize transformed RAW 264.7 macrophages into foam cells: Impact of pulmonary surfactant component dipalmitoylphosphatidylcholine.
Pyroptosis participates in PM(2.5)-induced air-blood barrier dysfunction.
Wnt3a knockdown promotes collagen type II expression in rat chondrocytes.
miR-let-7c-3p targeting on Egr-1 contributes to the committed differentiation of leukemia cells into monocyte/macrophages.
PM2.5-Induced Programmed Myocardial Cell Death via mPTP Opening Results in Deteriorated Cardiac Function in HFpEF Mice.
Ginsenoside CK induces apoptosis in triple-negative breast cancer cells by targeting glutamine metabolism.
Essential role of MALAT1 in reducing traumatic brain injury.
Polystyrene micro- and nano-particle coexposure injures fetal thalamus by inducing ROS-mediated cell apoptosis.
α-Terthienyl induces prostate cancer cell death through inhibiting androgen receptor expression.
Upregulated LINC01088 facilitates malignant phenotypes and immune escape of colorectal cancer by regulating microRNAs/G3BP1/PD-L1 axis.
LncRNA-CCAT1/miR-152-3p is involved in CSE-induced inflammation in HBE cells via regulating ERK signaling pathway.
Overexpression of heat shock protein 70 induces apoptosis of intestinal epithelial cells in heat-stressed pigs: A proteomics approach.
Artesunate Inhibits the Cell Growth in Colorectal Cancer by Promoting ROS-Dependent Cell Senescence and Autophagy.
Transient and Prolonged Activation of Wnt Signaling Contribute Oppositely to the Pathogenesis of Asherman's Syndrome.
Conditional knockout of ASK1 in microglia/macrophages attenuates epileptic seizures and long-term neurobehavioural comorbidities by modulating the inflammatory responses of microglia/macrophages.
Chemical profile and miscarriage prevention evaluation of Jiao-Ai Decoction, a classical traditional Chinese formula.
Expression Profile and Localization of SARS-CoV-2 Nonstructural Replicase Proteins in Infected Cells.
Mucin O-glycan-microbiota axis orchestrates gut homeostasis in a diarrheal pig model.
Assembly of Celastrol to Zeolitic Imidazolate Framework-8 by Coordination as a Novel Drug Delivery Strategy for Cancer Therapy.
Irisin attenuates P. gingivalis-suppressed osteogenic/cementogenic differentiation of periodontal ligament cells via p38 signaling pathway.
N-acetyldopamine dimer inhibits neuroinflammation through the TLR4/NF-κB and NLRP3/Caspase-1 pathways.
A positive feedback loop of ARF6 activates ERK1/2 signaling pathway via DUSP6 silencing to promote pancreatic cancer progression.
mTORC1 Mediates the Processes of Lysine Regulating Satellite Cells Proliferation, Apoptosis, and Autophagy.
Longterm Increased S100B Enhances Hippocampal Progenitor Cell Proliferation in a Transgenic Mouse Model.
Interferon-Stimulated Gene 15 Knockout in Mice Impairs IFNα-Mediated Antiviral Activity.
CD36 aggravates podocyte injury by activating NLRP3 inflammasome and inhibiting autophagy in lupus nephritis.
Toxoplasma gondii dense granule protein 3 promotes endoplasmic reticulum stress-induced apoptosis by activating the PERK pathway.
Overexpression of NCAPG in ovarian cancer is associated with ovarian cancer proliferation and apoptosis via p38 MAPK signaling pathway.
Aucubin promotes bone-fracture healing via the dual effects of anti-oxidative damage and enhancing osteoblastogenesis of hBM-MSCs.
BMP6 Promotes the Secretion of 17 Beta-Estradiol and Progesterone in Goat Ovarian Granulosa Cells.
LINC00941 promotes pancreatic cancer malignancy by interacting with ANXA2 and suppressing NEDD4L-mediated degradation of ANXA2.
Si-Wu Water Extracts Protect against Colonic Mucus Barrier Damage by Regulating Muc2 Mucin Expression in Mice Fed a High-Fat Diet.
Whole-exome sequencing and functional validation reveal a rare missense variant in MMP7 that confers ovarian endometriosis risk.
S-palmitoylation of PCSK9 induces sorafenib resistance in liver cancer by activating the PI3K/AKT pathway.
Porcine Enteric Coronavirus PEDV Induces the ROS-ATM and Caspase7-CAD-γH2AX Signaling Pathways to Foster Its Replication.
FAM107A Inactivation Associated with Promoter Methylation Affects Prostate Cancer Progression through the FAK/PI3K/AKT Pathway.
12/15-Lipoxygenase Regulation of Diabetic Cognitive Dysfunction Is Determined by Interfering with Inflammation and Cell Apoptosis.
Identification of HMGB2 associated with proliferation, invasion and prognosis in lung adenocarcinoma via weighted gene co-expression network analysis.
The comprehensive expression and functional analysis of m6A modification "readers" in hepatocellular carcinoma.
Preliminary evaluation of a small interfering RNA molecular probe targeting murine double minute 2 in breast cancer.
San-Wu-Huang-Qin decoction attenuates tumorigenesis and mucosal barrier impairment in the AOM/DSS model by targeting gut microbiome.
Ketogenesis acts as an endogenous protective programme to restrain inflammatory macrophage activation during acute pancreatitis.
HepaCAM‑PIK3CA axis regulates the reprogramming of glutamine metabolism to inhibit prostate cancer cell proliferation.
Acetyl CoA synthase 2 potentiates ATG5-induced autophagy against neuronal apoptosis after subarachnoid hemorrhage.
Necrostatin-1 Against Sevoflurane-Induced Cognitive Dysfunction Involves Activation of BDNF/TrkB Pathway and Inhibition of Necroptosis in Aged Rats.
High‑glucose microenvironment promotes perineural invasion of pancreatic cancer via activation of hypoxia inducible factor 1α.
Alda-1, an Aldehyde Dehydrogenase 2 Agonist, Improves Cutaneous Wound Healing by Activating Epidermal Keratinocytes via Akt/GSK-3β/β-Catenin Pathway.
Tumor-specific nitric oxide generator to amplify peroxynitrite based on highly penetrable nanoparticles for metastasis inhibition and enhanced cancer therapy.
Tumor-promoting mechanisms of macrophage-derived extracellular vesicles-enclosed microRNA-660 in breast cancer progression.
Nicotinamide riboside promotes Mfn2-mediated mitochondrial fusion in diabetic hearts through the SIRT1-PGC1α-PPARα pathway.
Synthesis of potent antagonists of receptors for growth hormone-releasing hormone with antitumor and anti-inflammatory activity.
U2 small nuclear RNA auxiliary factor 2, transcriptionally activated by the transcription factor Dp-1/E2F transcription factor 1 complex, enhances the growth and aerobic glycolysis of leiomyosarcoma cells.
Baicalein suppresses high glucose-induced inflammation and apoptosis in trophoblasts by targeting the miRNA-17-5p-Mfn1/2-NF-κB pathway.
Myeloid peroxisome proliferator-activated receptor α deficiency accelerates liver regeneration via IL-6/STAT3 pathway after 2/3 partial hepatectomy in mice.
Clostridium butyricum inhibits the progression of colorectal cancer and alleviates intestinal inflammation via the myeloid differentiation factor 88 (MyD88)-nuclear factor-kappa B (NF-κB) signaling pathway.
Ibandronate promotes autophagy by inhibiting Rac1-mTOR signaling pathway in vitro and in vivo.
SorCS3 promotes the internalization of p75(NTR) to inhibit GBM progression.
Hydroxysafflor Yellow A Blocks HIF-1α Induction of NOX2 and Protects ZO-1 Protein in Cerebral Microvascular Endothelium.
LncRNA WEE2-AS1 Knockdown Inhibits the Proliferation, Migration and 3 Invasion of Glioma Cells via Regulating miR-29b-2-5p/TPM3 Axis.
Cannabis suppresses antitumor immunity by inhibiting JAK/STAT signaling in T cells through CNR2.
Citrinin-Induced Hepatotoxicity in Mice Is Regulated by the Ca(2+)/Endoplasmic Reticulum Stress Signaling Pathway.
IL-37 isoform D acts as an inhibitor of soluble ST2 to boost type 2 immune homeostasis in white adipose tissue.
M1 Macrophages Enhance Survival and Invasion of Oral Squamous Cell Carcinoma by Inducing GDF15-Mediated ErbB2 Phosphorylation.
Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue.
Weighted gene co-expression network indicates that the DYNLL2 is an important regulator of chicken breast muscle development and is regulated by miR-148a-3p.
Platycodon grandiflorum root fermentation broth reduces inflammation in a mouse IBD model through the AMPK/NF-κB/NLRP3 pathway.
Sertad1 Induces Neurological Injury after Ischemic Stroke via the CDK4/p-Rb Pathway.
Map of Enteropathogenic Escherichia coli Targets Mitochondria and Triggers DRP-1-Mediated Mitochondrial Fission and Cell Apoptosis in Bovine Mastitis.
Pterostilbene and Its Derivative 3'-Hydroxypterostilbene Ameliorated Nonalcoholic Fatty Liver Disease Through Synergistic Modulation of the Gut Microbiota and SIRT1/AMPK Signaling Pathway.
The NDUFV2 gene silencing inhibits the proliferation of two drug-resistant cancer cell lines.
ASFV pD345L protein negatively regulates NF-κB signalling by inhibiting IKK kinase activity.
MFG-E8 alleviates intervertebral disc degeneration by suppressing pyroptosis and extracellular matrix degradation in nucleus pulposus cells via Nrf2/TXNIP/NLRP3 axis.
PCV2 and PRV Coinfection Induces Endoplasmic Reticulum Stress via PERK-eIF2α-ATF4-CHOP and IRE1-XBP1-EDEM Pathways.
Mettl14-Mediated m6A Modification Is Essential for Germinal Center B Cell Response.
Reticulon 2 promotes gastric cancer metastasis via activating endoplasmic reticulum Ca(2+) efflux-mediated ERK signalling.
Hydrogen-generating Si-based agent protects against skin flap ischemia-reperfusion injury in rats.
Let-7i-5p promotes a malignant phenotype in nasopharyngeal carcinoma via inhibiting tumor-suppressive autophagy.
Effects of Exogenous ATP on Melanoma Growth and Tumor Metabolism in C57BL/6 Mice.
Resveratrol attenuates methylmercury-induced neurotoxicity by modulating synaptic homeostasis.
Bisphenol A impairs macrophages through inhibiting autophagy via AMPK/mTOR signaling pathway and inducing apoptosis.
Adipose-derived stem cells alleviate liver injury induced by type 1 diabetes mellitus by inhibiting mitochondrial stress and attenuating inflammation.
Inhibition of Kelch-like epichlorohydrin-related protein 1 promotes the progression and drug resistance of lung adenocarcinoma.
Combination of ferulic acid, ligustrazine and tetrahydropalmatine inhibits invasion and metastasis through MMP/TIMP signaling in endometriosis.
Apigenin Alleviates Intervertebral Disc Degeneration via Restoring Autophagy Flux in Nucleus Pulposus Cells.
Single-Cell Analysis Identify Transcription Factor BACH1 as a Master Regulator Gene in Vascular Cells During Aging.
Hypoxia Activates Notch4 via ERK/JNK/P38 MAPK Signaling Pathways to Promote Lung Adenocarcinoma Progression and Metastasis.
CTRP1 Attenuates Cerebral Ischemia/Reperfusion Injury via the PERK Signaling Pathway.
Effect of Sirolimus on the Level of Peripheral Blood Lymphocyte Autophagy in Children With Systemic Lupus Erythematosus.
Targeted Deletion of Loxl3 by Col2a1-Cre Leads to Progressive Hearing Loss.
Osteopontin N-Terminal Function in an Abdominal Aortic Aneurysm From Apolipoprotein E-Deficient Mice.
Estrogen Receptor α Mediates Doxorubicin Sensitivity in Breast Cancer Cells by Regulating E-Cadherin.
Tooth Loss Induces Memory Impairment and Gliosis in App Knock-In Mouse Models of Alzheimer's Disease.
Celastrol Inhibits Canine Mammary Tumor Cells by Inducing Apoptosis via the Caspase Pathway.
Depiction of Aging-Based Molecular Phenotypes With Diverse Clinical Prognosis and Immunological Features in Gastric Cancer.
Identification of a Three-Glycolysis-Related lncRNA Signature Correlated With Prognosis and Metastasis in Clear Cell Renal Cell Carcinoma.
Comprehensive Analysis of the Potential Immune-Related Biomarker Transporter Associated With Antigen Processing 1 That Inhibits Metastasis and Invasion of Ovarian Cancer Cells.
RhoA/ROCK-YAP/TAZ Axis Regulates the Fibrotic Activity in Dexamethasone-Treated Human Trabecular Meshwork Cells.
Transcriptome Differences in Pig Tracheal Epithelial Cells in Response to Pasteurella Multocida Infection.
Indoleamine-2,3-Dioxygenase Activates Wnt/β-Catenin Inducing Kidney Fibrosis after Acute Kidney Injury.
Transient Receptor Potential Melastatin 7 Promotes Vascular Adventitial Fibroblasts Phenotypic Transformation and Inflammatory Reaction Induced by Mechanical Stretching Stress via p38 MAPK/JNK Pathway.
LncRNA WEE2-AS1 knockdown inhibits the proliferation, migration and invasion of glioma cells via regulating miR-29b-2-5p/TPM3 axis.
Study on Protection of Human Umbilical Vein Endothelial Cells from Amiodarone-Induced Damage by Intermedin through Activation of Wnt/β-Catenin Signaling Pathway.
Secretagogin Mediates the Regulatory Effect of Electroacupuncture on Hypothalamic-Pituitary-Adrenal Axis Dysfunction in Surgical Trauma.
Human Tissue Kallikrein 1 Is Downregulated in Elderly Human Prostates and Possesses Potential In Vitro Antioxidative and Antifibrotic Effects in Rodent Prostates.
Inhibition of Growth of Colon Tumors and Proliferation of HT-29 Cells by Warburgia ugandensis Extract through Mediating G(0)/G(1) Cell Cycle Arrest, Cell Apoptosis, and Intracellular ROS Generation.
The Formation of Melanocyte Apoptotic Bodies in Vitiligo and the Relocation of Vitiligo Autoantigens under Oxidative Stress.
HMSC-Derived Exosome Inhibited Th2 Cell Differentiation via Regulating miR-146a-5p/SERPINB2 Pathway.
MCU That Is Transcriptionally Regulated by Nrf2 Augments Malignant Biological Behaviors in Oral Squamous Cell Carcinoma Cells.
Decreased Expression of MPC2 Contributes to Aerobic Glycolysis and Colorectal Cancer Proliferation by Activating mTOR Pathway.
Antioral Squamous Cell Carcinoma Effects of Carvacrol via Inhibiting Inflammation, Proliferation, and Migration Related to Nrf2/Keap1 Pathway.
Metformin-Induced MicroRNA-34a-3p Downregulation Alleviates Senescence in Human Dental Pulp Stem Cells by Targeting CAB39 through the AMPK/mTOR Signaling Pathway.
DCI after Aneurysmal Subarachnoid Hemorrhage Is Related to the Expression of MFG-E8.
Anterior Gradient Protein 2 Promotes Mucosal Repair in Pediatric Ulcerative Colitis.
SPP1 Promotes Enzalutamide Resistance and Epithelial-Mesenchymal-Transition Activation in Castration-Resistant Prostate Cancer via PI3K/AKT and ERK1/2 Pathways.
Protective Effects of Huangqi Shengmai Yin on Type 1 Diabetes-Induced Cardiomyopathy by Improving Myocardial Lipid Metabolism.
Colonic Epithelial PHLPP2 Deficiency Promotes Colonic Epithelial Pyroptosis by Activating the NF-κB Signaling Pathway.
Exploring the Role and Mechanism of pAMPKα-Mediated Dysregulation of Brf1 and RNA Pol III Genes.
Berberine Reduces Renal Cell Pyroptosis in Golden Hamsters with Diabetic Nephropathy through the Nrf2-NLRP3-Caspase-1-GSDMD Pathway.
QiShenYiQi Pill Improves Myocardial Hypertrophy Caused by Pressure Overload in Rats.
Lycopene-Loaded Microemulsion Regulates Neurogenesis in Rats with Aβ-Induced Alzheimer's Disease Rats Based on the Wnt/β-catenin Pathway.
Saikosaponin D Inhibits the Proliferation and Promotes the Apoptosis of Rat Hepatic Stellate Cells by Inducing Autophagosome Formation.
Sesamin Protects against and Ameliorates Rat Intestinal Ischemia/Reperfusion Injury with Involvement of Activating Nrf2/HO-1/NQO1 Signaling Pathway.
Recombinant Human Growth Hormone Inhibits Lipotoxicity, Oxidative Stress, and Apoptosis in a Mouse Model of Diabetic Cardiomyopathy.
ARHGEF3 Associated with Invasion, Metastasis, and Proliferation in Human Osteosarcoma.
Electroacupuncture Preconditioning Reduces Oxidative Stress in the Acute Phase of Cerebral Ischemia-Reperfusion in Rats by Regulating Iron Metabolism Pathways.
miRNA-27a Transcription Activated by c-Fos Regulates Myocardial Ischemia-Reperfusion Injury by Targeting ATAD3a.
SIRT1 Attenuates Apoptosis of Nucleus Pulposus Cells by Targeting Interactions between LC3B and Fas under High-Magnitude Compression.
Curcumin Inhibits Replication of Human Parainfluenza Virus Type 3 by Affecting Viral Inclusion Body Formation.
Metformin Corrects Glucose Metabolism Reprogramming and NLRP3 Inflammasome-Induced Pyroptosis via Inhibiting the TLR4/NF-κB/PFKFB3 Signaling in Trophoblasts: Implication for a Potential Therapy of Preeclampsia.
LncRNA H19 Upregulation Participates in the Response of Glioma Cells to Radiation.
CircMETTL3, upregulated in a m6A-dependent manner, promotes breast cancer progression.
Thymoquinone Suppresses the Proliferation, Migration and Invasiveness through Regulating ROS, Autophagic Flux and miR-877-5p in Human Bladder Carcinoma Cells.
LINC00839 Regulates Proliferation, Migration, Invasion, Apoptosis and Glycolysis in Neuroblastoma Cells Through miR-338-3p/GLUT1 Axis.
Rufinamide (RUF) suppresses inflammation and maintains the integrity of the blood-brain barrier during kainic acid-induced brain damage.
New targets of morphine postconditioning protection of the myocardium in ischemia/reperfusion injury: Involvement of HSP90/Akt and C5a/NF-κB.
p53 Promoted Ferroptosis in Ovarian Cancer Cells Treated with Human Serum Incubated-Superparamagnetic Iron Oxides.
Self-Assembled DNA Nanostructure as a Carrier for Targeted siRNA Delivery in Glioma Cells.
Geniposide from Gardenia jasminoides var. radicans Makino Attenuates Myocardial Injury in Spontaneously Hypertensive Rats via Regulating Apoptotic and Energy Metabolism Signalling Pathway.
The Ghrelin/Growth Hormone Secretagogue Receptor System Is Involved in the Rapid and Sustained Antidepressant-Like Effect of Paeoniflorin.
GRIN2A Variants Associated With Idiopathic Generalized Epilepsies.
Gamma Radiation Induce Inflammasome Signaling and Pyroptosis in Microvascular Endothelial Cells.
Curcumin-Alleviated Osteoarthritic Progression in Rats Fed a High-Fat Diet by Inhibiting Apoptosis and Activating Autophagy via Modulation of MicroRNA-34a.
LncRNA MALAT1 promotes breast cancer progression by sponging miR101-3p to mediate mTOR/PKM2 signal transmission.
STAT5 inhibitor attenuates atherosclerosis via inhibition of inflammation: the role of STAT5 in atherosclerosis.
RNF128 suppresses the malignancy of colorectal cancer cells via inhibition of Wnt/β-catenin signaling.
Novel lncRNA LINC01614 Facilitates Bladder Cancer Proliferation, Migration and Invasion Through the miR-217/RUNX2/Wnt/β-Catenin Axis.
Calcitriol Alleviates MPP+- and MPTP-Induced Parthanatos Through the VDR/PARP1 Pathway in the Model of Parkinson's Disease.
Irisin Contributes to Neuroprotection by Promoting Mitochondrial Biogenesis After Experimental Subarachnoid Hemorrhage.
Ubenimex Suppresses the Ability of Migration and Invasion in Gastric Cancer Cells by Alleviating the Activity of the CD13/NAB1/MAPK Pathway.
ARRB1 Drives Gallbladder Cancer Progression by Facilitating TAK1/MAPK Signaling Activation.
Overexpression of TC2N is associated with poor prognosis in gastric cancer.
Nogo-B receptor is required for stabilizing TGF-β type I receptor and promotes the TGF-β1-induced epithelial-to-mesenchymal transition of non-small cell lung cancer.
A Mixture of Baicalein, Wogonin, and Oroxylin-A Inhibits EMT in the A549 Cell Line via the PI3K/AKT-TWIST1-Glycolysis Pathway.
Neutralizing Antibodies and Cellular Immune Responses Against SARS-CoV-2 Sustained One and a Half Years After Natural Infection.
Duck Plague Virus pUL48 Protein Activates the Immediate-Early Gene to Initiate the Transcription of the Virus Gene.
Activation of α7nAChR Protects Against Gastric Inflammation and Dysmotility in Parkinson's Disease Rats.
Resolvin D1 attenuates CCl4 Induced Liver Fibrosis by Inhibiting Autophagy-Mediated HSC activation via AKT/mTOR Pathway.
Punicalin Attenuates Breast Cancer-Associated Osteolysis by Inhibiting the NF-κB Signaling Pathway of Osteoclasts.
Sorafenib-Induced Autophagy Promotes Glycolysis by Upregulating the p62/HDAC6/HSP90 Axis in Hepatocellular Carcinoma Cells.
Menthol Targeting AMPK Alleviates the Inflammatory Response of Bovine Mammary Epithelial Cells and Restores the Synthesis of Milk Fat and Milk Protein.
Comprehensive Analysis of the Tumor Microenvironment and Ferroptosis-Related Genes Predict Prognosis with Ovarian Cancer.
Geniposide Ameliorates Liver Fibrosis Through Reducing Oxidative Stress and Inflammatory Respose, Inhibiting Apoptosis and Modulating Overall Metabolism.
The Panda-Derived Lactobacillus plantarum G201683 Alleviates the Inflammatory Response in DSS-Induced Panda Microbiota-Associated Mice.
Riclinoctaose Attenuates Renal Ischemia-Reperfusion Injury by the Regulation of Macrophage Polarization.
Transcriptomic Profiling Reveals the Antiapoptosis and Antioxidant Stress Effects of Fos in Ischemic Stroke.
Brd4 Regulates the Homeostasis of CD8(+) T-Lymphocytes and Their Proliferation in Response to Antigen Stimulation.
Hepatic Ischemia-Reperfusion Impairs Blood-Brain Barrier Partly Due to Release of Arginase From Injured Liver.
Targeting Wnt Signaling in the Tumor Immune Microenvironment to Enhancing EpCAM CAR T-Cell therapy.
The Abscopal Effects of Cranial Irradiation Induce Testicular Damage in Mice.
Internal Disulfide Bonding and Glycosylation of Interleukin-7 Protect Against Proteolytic Inactivation by Neutrophil Metalloproteinases and Serine Proteases.
DHAV-1 Blocks the Signaling Pathway Upstream of Type I Interferon by Inhibiting the Interferon Regulatory Factor 7 Protein.
Chlorogenic Acid Improves NAFLD by Regulating gut Microbiota and GLP-1.
Lidocaine Promoted Ferroptosis by Targeting miR-382-5p /SLC7A11 Axis in Ovarian and Breast Cancer.
Sinapic Acid Reduces Oxidative Stress and Pyroptosis via Inhibition of BRD4 in Alcoholic Liver Disease.
The Protective Effects of Sulforaphane on High-Fat Diet-Induced Obesity in Mice Through Browning of White Fat.
Yi-Qi-Jian-Pi Formula Suppresses RIPK1/RIPK3-Complex-Dependent Necroptosis of Hepatocytes Through ROS Signaling and Attenuates Liver Injury in Vivo and in Vitro.
Neuroprotective Effects of Oxymatrine on PI3K/Akt/mTOR Pathway After Hypoxic-Ischemic Brain Damage in Neonatal Rats.
Chronic Intermittent Hypobaric Hypoxia Decreases High Blood Pressure by Stabilizing the Vascular Renin-Angiotensin System in Spontaneously Hypertensive Rats.
Isovitexin Inhibits Ginkgolic Acids-Induced Inflammation Through Downregulating SHP2 Activation.
SNAPIN Regulates Cell Cycle Progression to Promote Pancreatic β Cell Growth.
FLI1 Induces Megakaryopoiesis Gene Expression Through WAS/WIP-Dependent and Independent Mechanisms; Implications for Wiskott-Aldrich Syndrome.
Histone demethylase JMJD3 protects against renal fibrosis by suppressing TGFβ and Notch signaling and preserving PTEN expression.
KDM6A promotes imatinib resistance through YY1-mediated transcriptional upregulation of TRKA independently of its demethylase activity in chronic myelogenous leukemia.
Suppressing Sart1 to modulate macrophage polarization by siRNA-loaded liposomes: a promising therapeutic strategy for pulmonary fibrosis.
ACSS3 represses prostate cancer progression through downregulating lipid droplet-associated protein PLIN3.
Growth hormone receptor disrupts glucose homeostasis via promoting and stabilizing retinol binding protein 4.
Bioengineering CXCR4-overexpressing cell membrane functionalized ROS-responsive nanotherapeutics for targeting cerebral ischemia-reperfusion injury.
Deciphering the autophagy regulatory network via single-cell transcriptome analysis reveals a requirement for autophagy homeostasis in spermatogenesis.
Epigenetically silenced linc00261 contributes to the metastasis of hepatocellular carcinoma via inducing the deficiency of FOXA2 transcription.
Glia Maturation Factor Beta as a Novel Biomarker and Therapeutic Target for Hepatocellular Carcinoma.
circRPS16 Promotes Proliferation and Invasion of Hepatocellular Carcinoma by Sponging miR-876-5p to Upregulate SPINK1.
CircFAM114A2 Promotes Cisplatin Sensitivity via miR-222-3p/P27 and miR-146a-5p/P21 Cascades in Urothelial Carcinoma.
Calcium Channel Protein ORAI1 Mediates TGF-β Induced Epithelial-to-Mesenchymal Transition in Colorectal Cancer Cells.
Yap1-2 Isoform Is the Primary Mediator in TGF-β1 Induced EMT in Pancreatic Cancer.
Subunit Vaccine ESAT-6:c-di-AMP Delivered by Intranasal Route Elicits Immune Responses and Protects Against Mycobacterium tuberculosis Infection.
The Anti-Inflammatory Effect and Mucosal Barrier Protection of Clostridium butyricum RH2 in Ceftriaxone-Induced Intestinal Dysbacteriosis.
PTIP Inhibits Cell Invasion in Esophageal Squamous Cell Carcinoma via Modulation of EphA2 Expression.
Inhibition of selenoprotein synthesis by Zika virus may contribute to congenital Zika syndrome and microcephaly by mimicking SELENOP knockout and the genetic disease PCCA.
Study on the effect of sevoflurane on the cognitive function of aged rats based on the activation of cortical microglia.
Curcumol inhibits ferritinophagy to restrain hepatocyte senescence through YAP/NCOA4 in non-alcoholic fatty liver disease.
Toxicity evaluation of mesoporous silica particles Santa Barbara No. 15 amorphous in human umbilical vein endothelial cells: influence of particle morphology.
Remarkable inhibition effects of afatinib alone or combining with paclitaxel in esophageal squamous cell carcinoma.
Endogenous reverse transcriptase and RNase H-mediated antiviral mechanism in embryonic stem cells.
TBC1 domain family member 23 interacts with Ras-related protein Rab-11A to promote poor prognosis of non-small-cell lung cancer via β1-integrin.
Salusin‑β participates in high glucose‑induced HK‑2 cell ferroptosis in a Nrf‑2‑dependent manner.
Mitochondrial calcium uniporter promotes cell proliferation and migration in esophageal cancer.
Protein arginine methyltransferase 5 mediates THP-1-derived macrophage activation dependent on NF-κB in endometriosis.
Treadmill exercise alleviates neuronal damage by suppressing NLRP3 inflammasome and microglial activation in the MPTP mouse model of Parkinson's disease.
Magnesium-L-threonate alleviate colonic inflammation and memory impairment in chronic-plus-binge alcohol feeding mice.
Probiotic fermentation of Ganoderma lucidum fruiting body extracts promoted its immunostimulatory activity in mice with dexamethasone-induced immunosuppression.
Blockade of GITRL/GITR signaling pathway attenuates house dust mite-induced allergic asthma in mice through inhibition of MAPKs and NF-κB signaling.
A methylation-driven gene panel predicts survival in patients with colon cancer.
Aloe-emodin prevents nerve injury and neuroinflammation caused by ischemic stroke via the PI3K/AKT/mTOR and NF-κB pathway.
Microglia-derived IL-1β promoted neuronal apoptosis through ER stress-mediated signaling pathway PERK/eIF2α/ATF4/CHOP upon arsenic exposure.
Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes.
LncRNA ZNFTR functions as an inhibitor in pancreatic cancer by modulating ATF3/ZNF24/VEGFA pathway.
3'HS1 CTCF binding site in human β-globin locus regulates fetal hemoglobin expression.
JaponiconeA induces apoptosis of bortezomib-sensitive and -resistant myeloma cells in vitro and in vivo by targeting IKK.
Sodium Tanshinone IIA Sulfonate Attenuates Cigarette Smoke Extract-Induced Mitochondrial Dysfunction, Oxidative Stress, and Apoptosis in Alveolar Epithelial Cells by Enhancing SIRT1 Pathway.
Nano chitosan-zinc complex improves the growth performance and antioxidant capacity of the small intestine in weaned piglets.
Different concentrations of C5a affect human dental pulp mesenchymal stem cells differentiation.
Proteomics identifies a novel role of fibrinogen-like protein 1 in Crohn's disease.
Mechanistic study of lncRNA UCA1 promoting growth and cisplatin resistance in lung adenocarcinoma.
Structural Studies of Water-Insoluble β-Glucan from Oat Bran and Its Effect on Improving Lipid Metabolism in Mice Fed High-Fat Diet.
Aged Ripe Pu-erh Tea Reduced Oxidative Stress-Mediated Inflammation in Dextran Sulfate Sodium-Induced Colitis Mice by Regulating Intestinal Microbes.
Reduced DAPK1 Expression Promotes Stem Cell-Like Characteristics of Prostate Cancer Cells by Activating ZEB1 via Hippo/YAP Signaling Pathway.
Raf1 interacts with OIP5 to participate in oxaliplatin-induced neuropathic pain.
Abnormal spatiotemporal expression pattern of progranulin and neurodevelopment impairment in VPA-induced ASD rat model.
Effect of different exercise training intensities on age-related cardiac damage in male mice.
Nintedanib Regulates GRK2 and CXCR2 to Reduce Neutrophil Recruitment in Endotoxin-Induced Lung Injury.
Betulinic acid induces autophagy-dependent apoptosis via Bmi-1/ROS/AMPK-mTOR-ULK1 axis in human bladder cancer cells.
MicroRNA-30c-5p protects against myocardial ischemia/reperfusion injury via regulation of Bach1/Nrf2.
Analysis of the microRNA and mRNA expression profile of ricin toxin-treated RAW264.7 cells reveals that miR-155-3p suppresses cell inflammation by targeting GAB2.
Resveratrol-mediated neurorestoration after cerebral ischemic injury - Sonic Hedgehog signaling pathway.
Phenotypic differences in the inner ears of CBA/CaJ and C57BL/6J mice carrying missense and single base pair deletion mutations in the Cdh23 gene.
Activation of CB2 receptor inhibits pyroptosis and subsequently ameliorates cecal ligation and puncture-induced sepsis.
Inhibition of TNFAIP1 ameliorates the oxidative stress and inflammatory injury in myocardial ischemia/reperfusion injury through modulation of Akt/GSK-3β/Nrf2 pathway.
Long-term in-vitro glucocorticoid treatment induces glucocorticoid resistance in canine mast cell tumors.
Astrocyte-selective STAT3 knockdown rescues methamphetamine withdrawal-disrupted spatial memory in mice via restoring the astrocytic capacity of glutamate clearance in dCA1.
Inhibition of ER stress attenuates kidney injury and apoptosis induced by 3-MCPD via regulating mitochondrial fission/fusion and Ca(2+) homeostasis.
The long non-coding RNA PFI protects against pulmonary fibrosis by interacting with splicing regulator SRSF1.
Exosomes derived from idiopathic gingival fibroma fibroblasts regulate gingival fibroblast proliferation and apoptosis.
Arsenic Trioxide Combining Leflunomide Activates Nrf2-ARE-HO-1 Signaling Pathway and Protects Heart Xenografts.
Sepsis induces muscle atrophy by inhibiting proliferation and promoting apoptosis via PLK1-AKT signalling.
Human umbilical cord mesenchymal stem cells ameliorate depression by regulating Jmjd3 and microglia polarization in myocardial infarction mice.
Dihydroartemisinin suppresses proliferation, migration, the Wnt/β-catenin pathway and EMT via TNKS in gastric cancer.
The role of alcohol dehydrogenase 1C in regulating inflammatory responses in ulcerative colitis.
Integrating systematic pharmacology-based strategy and experimental validation to explore the synergistic pharmacological mechanisms of Guanxin V in treating ventricular remodeling.
Myosin 1f-mediated activation of microglia contributes to the photoreceptor degeneration in a mouse model of retinal detachment.
Ferrostatin-1 alleviated TNBS induced colitis via the inhibition of ferroptosis.
EphA2 inhibits SRA01/04 cells apoptosis by suppressing autophagy via activating PI3K/Akt/mTOR pathway.
UM-6 induces autophagy and apoptosis via the Hippo-YAP signaling pathway in cervical cancer.
ZEB1 represses biogenesis of circ-DOCK5 to facilitate metastasis in esophageal squamous cell carcinoma via a positive feedback loop with TGF-β.
RCAN1.4 attenuates renal fibrosis through inhibiting calcineurin-mediated nuclear translocation of NFAT2.
Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation.
Hypoxic tubular epithelial cells regulate the angiogenesis of HMEC-1 cells via mediation of Rab7/MMP-2 axis.
Berberine Inhibits MDA-MB-231 Cells as an Agonist of G Protein-Coupled Estrogen Receptor 1.
Fructooligosaccharide supplementation alleviated the pathological immune response and prevented the impairment of intestinal barrier in DSS-induced acute colitis mice.
Gut microbiota-dependent catabolites of tryptophan play a predominant role in the protective effects of turmeric polysaccharides against DSS-induced ulcerative colitis.
Regulation of survivin protein stability by USP35 is evolutionarily conserved.
SMAD2 regulates testicular development and testosterone synthesis in Hu sheep.
METTL3 improves cardiomyocyte proliferation upon myocardial infarction via upregulating miR-17-3p in a DGCR8-dependent manner.
Chorionic villus-derived mesenchymal stem cell-mediated autophagy promotes the proliferation and invasiveness of trophoblasts under hypoxia by activating the JAK2/STAT3 signalling pathway.
Methamphetamine mediates apoptosis of vascular smooth muscle cells via the chop-related endoplasmic reticulum stress pathway.
Exercise Intervention Mitigates Pathological Liver Changes in NAFLD Zebrafish by Activating SIRT1/AMPK/NRF2 Signaling.
Effects of cannabinoid (CBD) on blood brain barrier permeability after brain injury in rats.
Melatonin alleviated oxidative stress induced by energy restriction on sheep Leydig cells through Sirt1/Sod2 pathway.
Vitamin A and retinoic acid accelerate the attenuation of intestinal adaptability upon feeding induced by high-fat diet in mice.
Downregulated fat mass and obesity-associated protein inhibits bone resorption and osteoclastogenesis by nuclear factor-kappa B inactivation.
miR‑4792 regulates inflammatory responses in Cryptococcus neoformans‑infected microglia.
Ginsenoside Rg1 attenuates mechanical stress-induced cardiac injury via calcium sensing receptor-related pathway.
Nicotinamide improves NAD(+) levels to protect against acetaminophen-induced acute liver injury in mice.
Loss of PHLDA1 has a protective role in OGD/R-injured neurons via regulation of the GSK-3β/Nrf2 pathway.
PHLDA3 inhibition protects against myocardial ischemia/reperfusion injury by alleviating oxidative stress and inflammatory response via the Akt/Nrf2 axis.
The immunosuppressive role of Edn3 overexpression in the melanoma microenvironment.
Ferroptosis is involved in the anti-tumor effect of lycorine in renal cell carcinoma cells.
Maiwei Yangfei decoction prevents bleomycin-induced pulmonary fibrosis in mice.
Hypercholesterolemia risk associated Abca6 does not regulate lipoprotein metabolism in mice or hamster.
Th17/IL-17 induces endothelial cell senescence via activation of NF-κB/p53/Rb signaling pathway.
Oxymatrine inhibits neuroinflammation byRegulating M1/M2 polarization in N9 microglia through the TLR4/NF-κB pathway.
Starvation induced autophagy promotes the progression of bladder cancer by LDHA mediated metabolic reprogramming.
Dual Hyaluronic Acid and Folic Acid Targeting pH-Sensitive Multifunctional 2DG@DCA@MgO-Nano-Core-Shell-Radiosensitizer for Breast Cancer Therapy.
Identification of a Proteomic Signature of Senescence in Primary Human Mammary Epithelial Cells.
Identification of candidate biomarker EMP3 and its prognostic potential in clear cell renal cell carcinoma.
CircCRIM1 promotes ovarian cancer progression by working as ceRNAs of CRIM1 and targeting miR-383-5p/ZEB2 axis.
SLC25A1 promotes tumor growth and survival by reprogramming energy metabolism in colorectal cancer.
miR-23a/b-3p promotes hepatic lipid accumulation by regulating Srebp-1c and Fas.
Tβ4 ameliorates oxidative damage and apoptosis through ERK/MAPK and 5-HT1A signaling pathway in Aβ insulted SH-SY5Y cells.
Exposure to melamine cyanuric acid in adult mice induced thyroid dysfunction and circadian rhythm disorder.
Verapamil ameliorates proximal tubular epithelial cells apoptosis and fibrosis in diabetic kidney.
Programmed cell death 5 improves skeletal muscle insulin resistance by inhibiting IRS-1 ubiquitination through stabilization of MDM2.
TM9SF4 is a novel regulator in lineage commitment of bone marrow mesenchymal stem cells to either osteoblasts or adipocytes.
AP39 ameliorates high fat diet-induced liver injury in young rats via alleviation of oxidative stress and mitochondrial impairment.
Down-regulation of EPB41L4A-AS1 mediated the brain aging and neurodegenerative diseases via damaging synthesis of NAD(+) and ATP.
TRIM15 promotes the invasion and metastasis of pancreatic cancer cells by mediating APOA1 ubiquitination and degradation.
UFL1 regulates milk protein and fat synthesis-related gene expression of bovine mammary epithelial cells probably via the mTOR signaling pathway.
Lipoxin A4 protects against paraquat‑induced acute lung injury by inhibiting the TLR4/MyD88‑mediated activation of the NF‑κB and PI3K/AKT pathways.
33-kDa ANXA3 isoform contributes to hepatocarcinogenesis via modulating ERK, PI3K/Akt-HIF and intrinsic apoptosis pathways.
GDF11 prevents the formation of thoracic aortic dissection in mice: Promotion of contractile transition of aortic SMCs.
Extracellular DJ-1 induces sterile inflammation in the ischemic brain.
Ubash3b promotes TPA-mediated suppression of leukemogenesis through accelerated downregulation of PKCδ protein.
MicroRNA-628-5p Facilitates Enterovirus 71 Infection by Suppressing TRAF3 Signaling.
Zinc-α2-glycoprotein relieved seizure-Induced neuronal glucose uptake impairment via insulin-like growth factor 1 receptor-regulated glucose transporter 3 expression.
Danthron ameliorates obesity and MAFLD through activating the interplay between PPARα/RXRα heterodimer and adiponectin receptor 2.
Human Cytomegalovirus Uses a Host Stress Response To Balance the Elongation of Saturated/Monounsaturated and Polyunsaturated Very-Long-Chain Fatty Acids.
Mechanistic insights into the anti-depressant effect of emodin: an integrated systems pharmacology study and experimental validation.
PET-CT and RNA sequencing reveal novel targets for acupuncture-induced lowering of blood pressure in spontaneously hypertensive rats.
Induced Pluripotent Stem Cell-Derived Conditioned Medium Promotes Endogenous Leukemia Inhibitory Factor to Attenuate Endotoxin-Induced Acute Lung Injury.
Evaluation of the nephrotoxicity and safety of low-dose aristolochic acid, extending to the use of Xixin (Asurum), by determination of methylglyoxal and d-lactate.
The novel prognostic risk factor STC2 can regulate the occurrence and progression of osteosarcoma via the glycolytic pathway.
Doxorubicin and PD-L1 siRNA co-delivery with stem cell membrane-coated polydopamine nanoparticles for the targeted chemoimmunotherapy of PCa bone metastases.
Essential Role of CRIM1 on Endometrial Receptivity in Goat.
Differentially expressed genes induced by β-caryophyllene in a rat model of cerebral ischemia-reperfusion injury.
Protective effect of recombinant Lactobacillus plantarum against H(2)O(2)-induced oxidative stress in HUVEC cells.
The HDAC and PI3K dual inhibitor CUDC-907 synergistically enhances the antileukemic activity of venetoclax in preclinical models of acute myeloid leukemia.
Glucagon-like peptide-1 (GLP-1) improved diabetic lung fibrosis via AMPK and microRNA-27a (miR-27a).
Angiotensin II-mediated improvement of renal mitochondrial function via the AMPK/PGC-1α/NRF-2 pathway is superior to norepinephrine in a rat model of septic shock associated with acute renal injury.
Low expression of BTN3A3 indicates poor prognosis and promotes cell proliferation, migration and invasion in non-small cell lung cancer.
Protein kinase D participates in cardiomyocyte hypertrophy by regulating extracellular signal-regulated and myocyte enhancer factor 2D.
The novel ALK inhibitor ZX-29 induces apoptosis through inhibiting ALK and inducing ROS-mediated endoplasmic reticulum stress in Karpas299 cells.
Effects of photoperiod on morphology and function in testis and epididymis of Cricetulus barabensis.
Resveratrol induces human colorectal cancer cell apoptosis by activating the mitochondrial pathway via increasing reactive oxygen species.
Curcumin suppresses colorectal tumorigenesis via the Wnt/β-catenin signaling pathway by downregulating Axin2.
Different effects of high-fat diets rich in different oils on lipids metabolism, oxidative stress and gut microbiota.
MALAT1 sponges miR-26a and miR-26b to regulate endothelial cell angiogenesis via PFKFB3-driven glycolysis in early-onset preeclampsia.
TDP-43 and PINK1 mediate CHCHD10(S59L) mutation-induced defects in Drosophila and in vitro.
The combination of G-CSF and AMD3100 mobilizes bone marrow-derived stem cells to protect against cisplatin-induced acute kidney injury in mice.
GR/NF-κB signaling pathway regulates hippocampal inflammatory responses in diabetic rats with chronic unpredictable mild stress.
Exposure to Melamine cyanuric acid in adolescent mice caused emotional disorder and behavioral disorder.
Identification and functional analysis of senescence-associated secretory phenotype of premature senescent hepatocytes induced by hexavalent chromium.
Overexpression of Annexin A2 promotes proliferation by forming a Glypican 1/c-Myc positive feedback loop: prognostic significance in human glioma.
Dietary seaweed-derived polysaccharides improve growth performance of weaned pigs through maintaining intestinal barrier function and modulating gut microbial populations.
Dihydroxyeicosatrienoic Acid, a Metabolite of Epoxyeicosatrienoic Acids Upregulates Endothelial Nitric Oxide Synthase Expression Through Transcription: Mechanism of Vascular Endothelial Function Protection.
CLIC1 Inhibition Protects Against Cellular Senescence and Endothelial Dysfunction Via the Nrf2/HO-1 Pathway.
Prenatal High-Sucrose Diet Induced Vascular Dysfunction in Thoracic Artery of Fetal Offspring.
Targeting the p300/NONO axis sensitizes melanoma cells to BRAF inhibitors.
Interleukin-1 induces receptor activator of nuclear factor-κB ligand-independent osteoclast differentiation in RAW264.7 cells.
The Role of Nrf2 on the Cognitive Dysfunction of High-fat Diet Mice Following Lead Exposure.
Isolation, characterization and transcriptome analysis of porcine deltacoronavirus strain HNZK-02 from Henan Province, China.
Melatonin inhibits lipid accumulation to repress prostate cancer progression by mediating the epigenetic modification of CES1.
Endoplasmic reticulum stress manipulates autophagic response that antagonizes polybrominated diphenyl ethers quinone induced cytotoxicity in microglial BV2 cells.
LINC00511 drives invasive behavior in hepatocellular carcinoma by regulating exosome secretion and invadopodia formation.
YTHDF1 promotes hepatocellular carcinoma progression via activating PI3K/AKT/mTOR signaling pathway and inducing epithelial-mesenchymal transition.
A metabolic data-driven systems pharmacology strategy for decoding and validating the mechanism of Compound Kushen Injection against HCC.
Antiviral effects of ergosterol peroxide in a pig model of porcine deltacoronavirus (PDCoV) infection involves modulation of apoptosis and tight junction in the small intestine.
Effects of total flavonoids from Eucommia ulmoides Oliv. leaves on polycystic ovary syndrome with insulin resistance model rats induced by letrozole combined with a high-fat diet.
CENPE contributes to pulmonary vascular remodeling in pulmonary hypertension.
Insulin injections inhibits PTZ-induced mitochondrial dysfunction, oxidative stress and neurological deficits via the SIRT1/PGC-1α/SIRT3 pathway.
Diosmetin ameliorate type 2 diabetic mellitus by up-regulating Corynebacterium glutamicum to regulate IRS/PI3K/AKT-mediated glucose metabolism disorder in KK-Ay mice.
PI3K/AKT pathway mediates the antidepressant- and anxiolytic-like roles of hydrogen sulfide in streptozotocin-induced diabetic rats via promoting hippocampal neurogenesis.
Cathepsin K deficiency promotes alveolar bone regeneration by promoting jaw bone marrow mesenchymal stem cells proliferation and differentiation via glycolysis pathway.
HORMAD1 promotes docetaxel resistance in triple negative breast cancer by enhancing DNA damage tolerance.
Hypoxic acclimation improves cardiac redox homeostasis and protects heart against ischemia-reperfusion injury through upregulation of O-GlcNAcylation.
The SESAME complex regulates cell senescence through the generation of acetyl-CoA.
Advanced maternal age causes premature placental senescence and malformation via dysregulated α-Klotho expression in trophoblasts.
SPOP negatively regulates Toll-like receptor-induced inflammation by disrupting MyD88 self-association.
Cimigenoside functions as a novel γ-secretase inhibitor and inhibits the proliferation or metastasis of human breast cancer cells by γ-secretase/Notch axis.
Medioresinol as a novel PGC-1α activator prevents pyroptosis of endothelial cells in ischemic stroke through PPARα-GOT1 axis.
Resveratrol attenuates manganese-induced oxidative stress and neuroinflammation through SIRT1 signaling in mice.
Shenmai injection improves doxorubicin cardiotoxicity via miR-30a/Beclin 1.
Ethanol extract of Ardisiae Japonicae Herba inhibits hepatoma carcinoma cell proliferation in vitro through regulating lipid metabolism.
Upregulation of RNA cap methyltransferase RNMT drives ribosome biogenesis during T cell activation.
Anoctamin 5 promotes osteosarcoma development by increasing degradation of Nel-like proteins 1 and 2.
Giardia duodenalis extracellular vesicles regulate the proinflammatory immune response in mouse macrophages in vitro via the MAPK, AKT and NF-κB pathways.
miR-126 Controls the Apoptosis and Proliferation of Immature Porcine Sertoli Cells by Targeting the PIK3R2 Gene through the PI3K/AKT Signaling Pathway.
Tumor protein D52 is upregulated in oral squamous carcinoma cells under hypoxia in a hypoxia-inducible-factor-independent manner and is involved in cell death resistance.
A novel chemical inhibitor suppresses breast cancer cell growth and metastasis through inhibiting HPIP oncoprotein.
UHRF2 commissions the completion of DNA demethylation through allosteric activation by 5hmC and K33-linked ubiquitination of XRCC1.
A clinically acceptable strategy for sensitizing anti-PD-1 treatment by hypoxia relief.
Neuroinflammation induces anxiety- and depressive-like behavior by modulating neuronal plasticity in the basolateral amygdala.
Limonin ameliorates dextran sulfate sodium-induced chronic colitis in mice by inhibiting PERK-ATF4-CHOP pathway of ER stress and NF-κB signaling.
Sunitinib malate inhibits intestinal tumor development in male Apc(Min/+) mice by down-regulating inflammation-related factors with suppressing β-cateinin/c-Myc pathway and re-balancing Bcl-6 and Caspase-3.
Astragaloside IV inhibits cell proliferation and metastasis of breast cancer via promoting the long noncoding RNA TRHDE-AS1.
A novel peptide relieves endothelial cell dysfunction in preeclampsia by regulating the PI3K/mTOR/HIF1α pathway.
MSH6 Aggravates the Hypoxic Microenvironment via Regulating HIF1A to Promote the Metastasis of Glioblastoma Multiforme.
Mefunidone ameliorates diabetic kidney disease in STZ and db/db mice.
Evaluation of piggyBac-mediated anti-CD19 CAR-T cells after ex vivo expansion with aAPCs or magnetic beads.
Carbohydrate response element-binding protein regulates lipid metabolism via mTOR complex1 in diabetic nephropathy.
Bone marrow stem cells therapy alleviates vascular injury in a chronic obstructive pulmonary disease‑obstructive sleep apnea overlap syndrome rat model.
Induction of autophagy by Beclin-1 in granulosa cells contributes to follicular progesterone elevation in ovarian endometriosis.
Protective effect of naringenin against cadmium-induced testicular toxicity in male SD rats.
The cGAS-STING signaling pathway contributes to the inflammatory response and autophagy in Aspergillus fumigatus keratitis.
EPZ015666, a selective protein arginine methyltransferase 5 (PRMT5) inhibitor with an antitumour effect in retinoblastoma.
IKKβ activation promotes amphisome formation and extracellular vesicle secretion in tumor cells.
Trichostatin A increases BDNF protein expression by improving XBP-1s/ATF6/GRP78 axis in Schwann cells of diabetic peripheral neuropathy.
Hypoxia-induced FOXO4/LDHA axis modulates gastric cancer cell glycolysis and progression.
A Cas9-transcription factor fusion protein enhances homology-directed repair efficiency.
Huaier Inhibits Proliferation, Migration, and Invasion of Cutaneous Squamous Cell Carcinoma Cells by Inhibiting the Methylation Levels of CDKN2A and TP53.
ING5 Inhibits Migration and Invasion of Esophageal Cancer Cells by Downregulating the IL-6/CXCL12 Signaling Pathway.
Obacunone Attenuates Liver Fibrosis with Enhancing Anti-Oxidant Effects of GPx-4 and Inhibition of EMT.
TRIM21-regulated Annexin A2 plasma membrane trafficking facilitates osteosarcoma cell differentiation through the TFEB-mediated autophagy.
Nrf2 overexpression increases risk of high tumor mutation burden in acute myeloid leukemia by inhibiting MSH2.
Sterol and oxysterol synthases near the ciliary base activate the Hedgehog pathway.
Autophagy impairment as a key feature for acetaminophen-induced ototoxicity.
Formaldehyde induces ferroptosis in hippocampal neuronal cells by upregulation of the Warburg effect.
Fucoxanthin extracted from Laminaria Japonica inhibits metastasis and enhances the sensitivity of lung cancer to Gefitinib.
A deafness-associated tRNA mutation caused pleiotropic effects on the m1G37 modification, processing, stability and aminoacylation of tRNAIle and mitochondrial translation.
Circ-NOLC1 promotes epithelial ovarian cancer tumorigenesis and progression by binding ESRP1 and modulating CDK1 and RhoA expression.
Cdk5-Mediated Phosphorylation of Sirt1 Contributes to Podocyte Mitochondrial Dysfunction in Diabetic Nephropathy.
A key role of gut microbiota-vagus nerve/spleen axis in sleep deprivation-mediated aggravation of systemic inflammation after LPS administration.
Let-7a regulates EV secretion and mitochondrial oxidative phosphorylation by targeting SNAP23 in colorectal cancer.
Bushen Huoxue recipe attenuates early pregnancy loss via activating endometrial COX2-PGE2 angiogenic signaling in mice.
CDCA4 suppresses epithelial-mesenchymal transtion (EMT) and metastasis in Non-small cell lung cancer through modulating autophagy.
L-type amino acid transporter 1 is associated with chemoresistance in breast cancer via the promotion of amino acid metabolism.
Changes in the prefrontal cortex after the hippocampus was injected with Aβ(25-35) via the P35/P25-CDK5-Tau hyperphosphorylation signaling pathway.
Eradicating intracellular MRSA via targeted delivery of lysostaphin and vancomycin with mannose-modified exosomes.
Metformin alleviates high glucose-induced ER stress and inflammation by inhibiting the interaction between caveolin1 and AMPKα in rat astrocytes.
ActivinA activates Notch1-Shh signaling to regulate proliferation in C2C12 skeletal muscle cells.
Disrupted eNOS activity and expression account for vasodilator dysfunction in different stage of sepsis.
Anti-renal interstitial fibrosis effect of norcantharidin is exerted through inhibition of PP2Ac-mediated C-terminal phosphorylation of Smad3.
Syndecan 4 contributes to osteoclast differentiation induced by RANKL through enhancing autophagy.
Type 1 interferon aggravates lipopolysaccharide-induced sepsis through upregulating Caspase-11 and Gasdermin D.
Effect of claudin 1 on cell proliferation, migration and apoptosis in human cervical squamous cell carcinoma.
Sodium alginate/collagen hydrogel loaded with human umbilical cord mesenchymal stem cells promotes wound healing and skin remodeling.
Downregulating lncRNA PRNCR1 ameliorates LPS-induced pulmonary vascular endothelial cell injury by modulating miR-330-5p/TLR4 axis.
NPM1 mutant maintains ULK1 protein stability via TRAF6-dependent ubiquitination to promote autophagic cell survival in leukemia.
Cell membrane-encapsulated magnetic nanoparticles for enhancing natural killer cell-mediated cancer immunotherapy.
BML-111, the lipoxin A(4) agonist, modulates VEGF or CoCl(2)-induced migration, angiogenesis and permeability in tumor-derived endothelial cells.
MicroRNA‑338‑3p regulates age‑associated osteoporosis via targeting PCSK5.
Luteolin attenuates angiotensin II‑induced renal damage in apolipoprotein E‑deficient mice.
Exercise reduces hyperlipidemia-induced kidney damage in apolipoprotein E-deficient mice.
F-Box protein 4 inhibits progression of papillary thyroid cancer.
Novel clerodane-type diterpenoid Cintelactone A suppresses lipopolysaccharide -induced inflammation by promoting ubiquitination, proteasomal degradation of TRAF6.
Osteogenic differentiation and calcification of human aortic smooth muscle cells is induced by the RCN2/STAT3/miR-155-5p feedback loop.
Study on the protective effect and mechanism of Dicliptera chinensis (L.) Juss (Acanthaceae) polysaccharide on immune liver injury induced by LPS.
Impact of knockdown LincRNA-Cox2 on apoptosis of macrophage infected with Bacillus Calmette-Guérin.
Bach2 overexpression represses Th9 cell differentiation by suppressing IRF4 expression in systemic lupus erythematosus.
Hypothermic oxygenated perfusion inhibits HECTD3-mediated TRAF3 polyubiquitination to alleviate DCD liver ischemia-reperfusion injury.
An ESCRT-dependent step in fatty acid transfer from lipid droplets to mitochondria through VPS13D-TSG101 interactions.
SEPHS1 promotes SMAD2/3/4 expression and hepatocellular carcinoma cells invasion.
Anti-NMDAR encephalitis induced in mice by active immunization with a peptide from the amino-terminal domain of the GluN1 subunit.
Macrophage migration inhibitory factor activates the inflammatory response in joint capsule fibroblasts following post-traumatic joint contracture.
Rational design and synthesis of 6-aryl-6H-benzo[c]chromenes as non-steroidal progesterone receptor antagonists for use against cancers.
A genome-wide CRISPR screen identifies host factors that regulate SARS-CoV-2 entry.
Stabilizing mast cells improves acute lung injury after orthotopic liver transplantation via promotion of apoptosis in polymorphonuclear neutrophils.
Prenylated xanthones from mangosteen (Garcinia mangostana) activate the AhR and Nrf2 pathways and protect intestinal barrier integrity in HT-29 cells.
ABIN-1 is a key regulator in RIPK1-dependent apoptosis (RDA) and necroptosis, and ABIN-1 deficiency potentiates necroptosis-based cancer therapy in colorectal cancer.
Ataxia-telangiectasia mutated interacts with Parkin and induces mitophagy independent of kinase activity. Evidence from mantle cell lymphoma.
Compound Kushen Injection intervenes metabolic reprogramming and epithelial-mesenchymal transition of HCC via regulating β-catenin/c-Myc signaling.
Dendrobium nobile Lindl alkaloid attenuates 6-OHDA-induced dopamine neurotoxicity.
Simiao Qingwen Baidu decoction inhibits Epstein-Barr virus-induced B lymphoproliferative disease and lytic viral replication.
Chrysanthemi Flos extract alleviated acetaminophen-induced rat liver injury via inhibiting oxidative stress and apoptosis based on network pharmacology analysis.
Bone marrow macrophage-derived exosomal miR-143-5p contributes to insulin resistance in hepatocytes by repressing MKP5.
Hsa_circ_0042823 accelerates cancer progression via miR-877-5p/FOXM1 axis in laryngeal squamous cell carcinoma.
Azathioprine pretreatment ameliorates myocardial ischaemia reperfusion injury in diabetic rats by reducing oxidative stress, apoptosis, and inflammation.
Triptolide regulates oxidative stress and inflammation leading to hepatotoxicity via inducing CYP2E1.
Non-canonical activation of the ER stress sensor ATF6 by Legionella pneumophila effectors.
Ramelteon Mitigates Free Fatty Acid (FFA)-Induced Attachment of Monocytes to Brain Vascular Endothelial Cells.
Acetabular development and fate of inverted limbus in rabbits: Experimental observation from an animal model.
Bergenin alleviates H(2) O(2) -induced oxidative stress and apoptosis in nucleus pulposus cells: Involvement of the PPAR-γ/NF-κB pathway.
ChREBP deficiency alleviates apoptosis by inhibiting TXNIP/oxidative stress in diabetic nephropathy.
Low EGR1 expression predicts poor prognosis in clear cell renal cell carcinoma.
TRIP4 transcriptionally activates DDIT4 and subsequent mTOR signaling to promote glioma progression.
Pretreatment of Indobufen and Aspirin and their Combinations with Clopidogrel or Ticagrelor Alleviates Inflammasome Mediated Pyroptosis Via Inhibiting NF-κB/NLRP3 Pathway in Ischemic Stroke.
Empagliflozin protects diabetic pancreatic tissue from damage by inhibiting the activation of the NLRP3/caspase-1/GSDMD pathway in pancreatic β cells: in vitro and in vivo studies.
The effects of Omarigliptin on promoting osteoblastic differentiation.
High expression of transmembrane P24 trafficking protein 9 predicts poor prognosis in breast carcinoma.
MiR-130a-3p suppresses colorectal cancer growth by targeting Wnt Family Member 1 (WNT1).
Silencing circular RNA circ_0054537 and upregulating microRNA-640 suppress malignant progression of renal cell carcinoma via regulating neuronal pentraxin-2 (NPTX2).
Soy isoflavones alleviate polycystic ovary syndrome in rats by regulating NF- κB signaling pathway.
Hypoxia-inducible factor-1alpha protects the liver against ischemia-reperfusion injury by regulating the A2B adenosine receptor.
M2 Macrophage-derived exosomal miR-501 contributes to pubococcygeal muscle regeneration.
Biomimetic amphiphilic FAAP NPs nanoparticles: Synthesis, characterization and antivirus activity.
Screening and Identification of Differential Ovarian Proteins before and after Induced Ovulation via Seminal Plasma in Bactrian Camels.
Fyn kinase regulates dopaminergic neuronal apoptosis in animal and cell models of high glucose (HG) treatment.
Long non-coding RNA CRNDE exacerbates NPC advancement mediated by the miR-545-5p/CCND2 axis.
T-2 Toxin Induces Ferroptosis by Increasing Lipid Reactive Oxygen Species (ROS) and Downregulating Solute Carrier Family 7 Member 11 (SLC7A11).
Esophageal Cancer Stem-like Cells Resist Ferroptosis-Induced Cell Death by Active Hsp27-GPX4 Pathway.
Urolithin a alleviates oxidative stress-induced senescence in nucleus pulposus-derived mesenchymal stem cells through SIRT1/PGC-1α pathway.
Aureonitol Analogues and Orsellinic Acid Esters Isolated from Chaetomium elatum and Their Antineuroinflammatory Activity.
Dietary supplementation of inulin alleviates metabolism disorders in gestational diabetes mellitus mice via RENT/AKT/IRS/GLUT4 pathway.
Black Tea Alleviates Particulate Matter-Induced Lung Injury via the Gut-Lung Axis in Mice.
GADD34-mediated dephosphorylation of eIF2α facilitates pseudorabies virus replication by maintaining de novo protein synthesis.
Expression, purification and characterisation of a human anti-CDK4 single-chain variable fragment antibody.
Tryptophanyl tRNA Synthetase from Human Macrophages Infected by Porphyromonas gingivalis Induces a Proinflammatory Response Associated with Atherosclerosis.
Oxygen nanocarrier broke the hypoxia trap of solid tumors and rescued transfection efficiency for gene therapy.
Aroylhydrazone Diorganotin Complexes Causes DNA Damage and Apoptotic Cell Death: From Chemical Synthesis to Biochemical Effects.
Calcium alleviates fluoride-induced kidney damage via FAS/FASL, TNFR/TNF, DR5/TRAIL pathways in rats.
Circular RNA circEsyt2 regulates vascular smooth muscle cell remodeling via splicing regulation.
BLM helicase inhibition synergizes with PARP inhibition to improve the radiosensitivity of olaparib resistant non-small cell lung cancer cells by inhibiting homologous recombination repair.
Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Rac Exchanger 2 Protein Facilitates Glioma Progression via Akt and Stat3 Signaling.
Guanosine and uridine alleviate airway inflammation via inhibition of the MAPK and NF-κB signals in OVA-induced asthmatic mice.
Diosgenin Protects Against Kidney Injury and Mitochondrial Apoptosis Induced by 3-MCPD Through the Regulation of ER Stress, Ca(2+) Homeostasis, and Bcl2 Expression.
Dental pulp stem cell-derived exosomes alleviate cerebral ischaemia-reperfusion injury through suppressing inflammatory response.
Hippocampal CA1 theta burst-induced LTP from weaning to adulthood: Cellular and molecular mechanisms in young male rats revisited.
Glutaredoxin 1 protects neurons from oxygen-glucose deprivation/reoxygenation (OGD/R)-induced apoptosis and oxidative stress via the modulation of GSK-3β/Nrf2 signaling.
MicroRNA-122 contributes to lipopolysaccharide-induced acute kidney injury via down-regulating the vitamin D receptor in the kidney.
H(2)S Attenuates Sleep Deprivation-Induced Cognitive Impairment by Reducing Excessive Autophagy via Hippocampal Sirt-1 in WISTAR RATS.
CQMUH-011 Inhibits LPS-Induced Microglia Activation and Ameliorates Brain Ischemic Injury in Mice.
Quercetin hinders microglial activation to alleviate neurotoxicity via the interplay between NLRP3 inflammasome and mitophagy.
The p53/p21/p16 and PI3K/Akt signaling pathways are involved in the ameliorative effects of maltol on D-galactose-induced liver and kidney aging and injury.
LncRNA-AC006129.1 reactivates a SOCS3-mediated anti-inflammatory response through DNA methylation-mediated CIC downregulation in schizophrenia.
The molecular mechanism underlying mitophagy-mediated hippocampal neuron apoptosis in diabetes-related depression.
Resveratrol affects the expression of uric acid transporter by improving inflammation.
Aggravation of hepatic ischemia‑reperfusion injury with increased inflammatory cell infiltration is associated with the TGF‑β/Smad3 signaling pathway.
miR-320a in serum exosomes promotes myocardial fibroblast proliferation via regulating the PIK3CA/Akt/mTOR signaling pathway in HEH2 cells.
Augmenter of liver regeneration ameliorates ischemia-reperfusion injury in steatotic liver via inhibition of the TLR4/NF-κB pathway.
DNMT1-mediated PPARα methylation aggravates damage of retinal tissues in diabetic retinopathy mice.
Ginsenoside Rg5 Improves Insulin Resistance and Mitochondrial Biogenesis of Liver via Regulation of the Sirt1/PGC-1α Signaling Pathway in db/db Mice.
The screening of drug-induced nephrotoxicity using gold nanocluster-based ratiometric fluorescent probes.
YWHAZ interacts with DAAM1 to promote cell migration in breast cancer.
Effects of RNA methylation N6-methyladenosine regulators on malignant progression and prognosis of melanoma.
The Performance of HepG2 and HepaRG Systems through the Glass of Acetaminophen-Induced Toxicity.
USP15 participates in DBP-induced testicular oxidative stress injury through regulating the Keap1/Nrf2 signaling pathway.
Reactive microglia enhance the transmission of exosomal α-synuclein via toll-like receptor 2.
Expression pattern and regulatory effect of lysine-specific demethylase 2A gene in clear cell renal cell carcinoma.
Serum exosomal pregnancy zone protein as a promising biomarker in inflammatory bowel disease.
KIM-1-mediated anti-inflammatory activity is preserved by MUC1 induction in the proximal tubule during ischemia-reperfusion injury.
CIHH protects the heart against left ventricular remodelling and myocardial fibrosis by balancing the renin-angiotensin system in SHR.
Virtual screening identified natural Keap1-Nrf2 PPI inhibitor alleviates inflammatory osteoporosis through Nrf2-mir214-Traf3 axis.
The canonical smooth muscle cell marker TAGLN is present in endothelial cells and is involved in angiogenesis.
Contribution of the NLRP3/IL-1β axis to impaired vasodilation in sepsis through facilitation of eNOS proteolysis and the protective role of melatonin.
Autocrined leptin promotes proliferation of non-small cell lung cancer (NSCLC) via PI3K/AKT and p53 pathways.
Morusin inhibits the growth of human colorectal cancer HCT116‑derived sphere‑forming cells via the inactivation of Akt pathway.
MMP11 promotes the proliferation and progression of breast cancer through stabilizing Smad2 protein.
BOP1 Silencing Suppresses Gastric Cancer Proliferation through p53 Modulation.
Effect of luteinizing hormone concentration on transcriptome and subcellular organelle phenotype of ovarian granulosa cells.
CRSP8 promotes thyroid cancer progression by antagonizing IKKα-induced cell differentiation.
Enhanced response to PD-L1 silencing by modulation of TME via balancing glucose metabolism and robust co-delivery of siRNA/Resveratrol with dual-responsive polyplexes.
Zinc provides neuroprotection by regulating NLRP3 inflammasome through autophagy and ubiquitination in a spinal contusion injury model.
Honokiol induces paraptosis-like cell death of acute promyelocytic leukemia via mTOR & MAPK signaling pathways activation.
Oxymatrine reduces expression of programmed death-ligand 1 by promoting DNA demethylation in colorectal cancer cells.
Abnormal Glu/mGluR(2/3)/PI3K pathway in the hippocampal neurovascular unit leads to diabetes-related depression.
Involvement of NADPH oxidase in patulin-induced oxidative damage and cytotoxicity in HEK293 cells.
SPT6 recruits SND1 to co-activate human telomerase reverse transcriptase to promote colon cancer progression.
Change on apoptosis, autophagy and mitochondria of the Harderian gland in Cricetulus barabensis during age.
Downregulation of circular RNA circDOCK7 identified from diabetic rats after sleeve gastrectomy contributes to hepatocyte apoptosis through regulating miR-139-3p and MCM3.
Smooth muscle-specific HuR knockout induces defective autophagy and atherosclerosis.
GCG inhibits SARS-CoV-2 replication by disrupting the liquid phase condensation of its nucleocapsid protein.
KLF5-mediated Eppk1 expression promotes cell proliferation in cervical cancer via the p38 signaling pathway.
Dexmedetomidine protects SH-SY5Y cells against MPP(+) -induced declining of mitochondrial membrane potential and cell cycle deficits.
Xanthine oxidase inhibitory activity and antihyperuricemic effect of Moringa oleifera Lam. leaf hydrolysate rich in phenolics and peptides.
cAMP-PKA signaling is involved in regulation of spinal HCN channels function in diabetic neuropathic pain.
The SRSF1/circATP5B/miR-185-5p/HOXB5 feedback loop regulates the proliferation of glioma stem cells via the IL6-mediated JAK2/STAT3 signaling pathway.
Spleen Tyrosine Kinase Mediates Microglial Activation in Mice With Diabetic Retinopathy.
REG γ knockdown suppresses proliferation by inducing apoptosis and cell cycle arrest in osteosarcoma.
Glutamate-Cysteine Ligase Catalytic Subunit Attenuated Hepatitis C Virus-Related Liver Fibrosis and Suppressed Endoplasmic Reticulum Stress.
Promotion of cadmium uptake and cadmium-induced toxicity by the copper transporter CTR1 in HepG2 and ZFL cells.
The Novel Synthetic Triterpene Methyl 3β-O-[4-(2-Aminoethylamino)-4-oxo-butyryl]olean-12-ene-28-oate Inhibits Breast Tumor Cell Growth in Vitro and in Vivo.
Baicalin Inhibits Coxsackievirus B3 Replication by Reducing Cellular Lipid Synthesis.
Anti-inflammation and anti-apoptosis effects of growth arrest-specific protein 6 in acute liver injury induced by LPS/D-GalN in mice.
Systematic investigation of biomarker-like role of ARHGDIB in breast cancer.
Xiao-Qing-Long-Tang Maintains Cardiac Function during Heart Failure with Reduced Ejection Fraction in Salt-Sensitive Rats by Regulating the Imbalance of Cardiac Sympathetic Innervation.
Phloretin Modulates Human Th17/Treg Cell Differentiation In Vitro via AMPK Signaling.
Role of Nrf2 in Lipopolysaccharide-Induced Acute Kidney Injury: Protection by Human Umbilical Cord Blood Mononuclear Cells.
Heme Oxygenase-1 Suppresses Wnt Signaling Pathway in Nonalcoholic Steatohepatitis-Related Liver Fibrosis.
Thymoquinone Protects against Hyperlipidemia-Induced Cardiac Damage in Low-Density Lipoprotein Receptor-Deficient (LDL-R(-/-)) Mice via Its Anti-inflammatory and Antipyroptotic Effects.
Electroacupuncture Pretreatment Alleviates LPS-Induced Acute Respiratory Distress Syndrome via Regulating the PPAR Gamma/NF-Kappa B Signaling Pathway.
Silencing ARAF Suppresses the Malignant Phenotypes of Gallbladder Cancer Cells.
Ellagic Acid Protects Dopamine Neurons via Inhibition of NLRP3 Inflammasome Activation in Microglia.
miR-876 Inhibits EMT and Liver Fibrosis via POSTN to Suppress Metastasis in Hepatocellular Carcinoma.
Anti-Inflammatory and Antioxidant Effect of Eucommia ulmoides Polysaccharide in Hepatic Ischemia-Reperfusion Injury by Regulating ROS and the TLR-4-NF-κB Pathway.
Effects of Hydrogen-rich Water on the PI3K/AKT Signaling Pathway in Rats with Myocardial Ischemia-reperfusion Injury.
A glycolysis-based 4-mRNA signature correlates with the prognosis and cell cycle process in patients with bladder cancer.
Structure-based discovery of neoandrographolide as a novel inhibitor of Rab5 to suppress cancer growth.
Nicotinamide Riboside Enhances Mitochondrial Proteostasis and Adult Neurogenesis through Activation of Mitochondrial Unfolded Protein Response Signaling in the Brain of ALS SOD1(G93A) Mice.
Methylglyoxal and D-lactate in cisplatin-induced acute kidney injury: Investigation of the potential mechanism via fluorogenic derivatization liquid chromatography-tandem mass spectrometry (FD-LC-MS/MS) proteomic analysis.
Interferon regulatory factor 7 mediates obesity-associated MCP-1 transcription.
MicroRNA-9 mediated the protective effect of ferulic acid on hypoxic-ischemic brain damage in neonatal rats.
The effect of autophagy and mitochondrial fission on Harderian gland is greater than apoptosis in male hamsters during different photoperiods.
Utilizing methylglyoxal and D-lactate in urine to evaluate saikosaponin C treatment in mice with accelerated nephrotoxic serum nephritis.
Effect of prednisolone on glyoxalase 1 in an inbred mouse model of aristolochic acid nephropathy using a proteomics method with fluorogenic derivatization-liquid chromatography-tandem mass spectrometry.
Protective effects of essential oil from Fructus Alpiniae zerumbet on retinal Müller gliosis via the PPAR-γ-p-CREB signaling pathway.
MicroRNA 885-5p Inhibits Hepatocellular Carcinoma Metastasis by Repressing AEG1.
Bufalin Induces Glioma Cell Death by Apoptosis or Necroptosis.
The Acetone Indigo Red Dehydrating Agent IF203 Induces HepG2 Cell Death Through Cell Cycle Arrest, Autophagy and Apoptosis.
MicroRNA-375 Targets ATG14 to Inhibit Autophagy and Sensitize Hepatocellular Carcinoma Cells to Sorafenib.
Dihydroartemisinin Prevents Progression and Metastasis of Head and Neck Squamous Cell Carcinoma by Inhibiting Polarization of Macrophages in Tumor Microenvironment.
Proteomics Analysis of Brain Tissue in a Rat Model of Ischemic Stroke in the Acute Phase.
The Regulatory Mechanism and Biological Significance of Mitochondrial Calcium Uniporter in the Migration, Invasion, Angiogenesis and Growth of Gastric Cancer.
Melatonin ameliorates hyperglycaemia-induced renal inflammation by inhibiting the activation of TLR4 and TGF-β1/Smad3 signalling pathway.
Fenofibrate-induced mitochondrial dysfunction and metabolic reprogramming reversal: the anti-tumor effects in gastric carcinoma cells mediated by the PPAR pathway.
Selaginellin B induces apoptosis and autophagy in pancreatic cancer cells via the JAK2/STAT3 signaling pathway.
Identification of FADS1 Through Common Gene Expression Profiles for Predicting Survival in Patients with Bladder Cancer.
Blocking circ_0013912 Suppressed Cell Growth, Migration and Invasion of Pancreatic Ductal Adenocarcinoma Cells in vitro and in vivo Partially Through Sponging miR-7-5p.
The Clinical Relevance and Function of Krüppel-Like Factor 16 in Breast Cancer.
The LINC00365/SCGB2A1 (Mammaglobin B) Axis Down-Regulates NF-κB Signaling and Is Associated with the Progression of Gastric Cancer.
Inhibition of Skp2 Sensitizes Chronic Myeloid Leukemia Cells to Imatinib.
LINC00963 Promotes Ovarian Cancer Proliferation, Migration and EMT via the miR-378g /CHI3L1 Axis.
Dl-3-n-Butylphthalide Promotes Remyelination and Suppresses Inflammation by Regulating AMPK/SIRT1 and STAT3/NF-κB Signaling in Chronic Cerebral Hypoperfusion.
Hypoxia-induced MFAP5 Promotes Tumor Migration and Invasion via AKT Pathway in Head and Neck Squamous Cell Carcinoma.
Weighted gene co-expression network analysis identifies CCNA2 as a treatment target of prostate cancer through inhibiting cell cycle.
miRNA-182 regulated MTSS1 inhibits proliferation and invasion in Glioma Cells.
Isoquercitrin Ameliorates Cisplatin-Induced Nephrotoxicity Via the Inhibition of Apoptosis, Inflammation, and Oxidative Stress.
Hydrogen Sulfide Attenuates High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease by Inhibiting Apoptosis and Promoting Autophagy via Reactive Oxygen Species/Phosphatidylinositol 3-Kinase/AKT/Mammalian Target of Rapamycin Signaling Pathway.
Integrated Analysis of Key Genes and Pathways Involved in Fetal Growth Restriction and Their Associations With the Dysregulation of the Maternal Immune System.
Mitochondrial DNA Haplogroup M7 Confers Disability in a Chinese Aging Population.
The Human-Specific STING Agonist G10 Activates Type I Interferon and the NLRP3 Inflammasome in Porcine Cells.
Notoginsenoside R1 Protects Against the Acrylamide-Induced Neurotoxicity via Upregulating Trx-1-Mediated ITGAV Expression: Involvement of Autophagy.
Fisetin Alleviated Bleomycin-Induced Pulmonary Fibrosis Partly by Rescuing Alveolar Epithelial Cells From Senescence.
Progesterone Regulates Glucose Metabolism Through Glucose Transporter 1 to Promote Endometrial Receptivity.
Photoperiod Affects Harderian Gland Morphology and Secretion in Female Cricetulus barabensis: Autophagy, Apoptosis, and Mitochondria.
Characterization and Neuroprotection Potential of Seleno-Polymannuronate.
Identification of Immune-Related Genes Contributing to the Development of Glioblastoma Using Weighted Gene Co-expression Network Analysis.
Liraglutide Ameliorates Erectile Dysfunction via Regulating Oxidative Stress, the RhoA/ROCK Pathway and Autophagy in Diabetes Mellitus.
NNK-mediated upregulation of DEPDC1 stimulates the progression of oral squamous cell carcinoma by inhibiting CYP27B1 expression.
Novel ESCC-related gene ZNF750 as potential Prognostic biomarker and inhibits Epithelial-Mesenchymal Transition through directly depressing SNAI1 promoter in ESCC.
MicroRNA-590-3p inhibits invasion and metastasis in triple-negative breast cancer by targeting Slug.
An ultrasensitive hybridization chain reaction-amplified CRISPR-Cas12a aptasensor for extracellular vesicle surface protein quantification.
Hsp90 inhibitor HSP990 in very low dose upregulates EAAT2 and exerts potent antiepileptic activity.
LincRNA00494 Suppresses Non-small Cell Lung Cancer Cell Proliferation by Regulating SRCIN1 Expression as a ceRNA.
Critical roles of microRNA-141-3p and CHD8 in hypoxia/reoxygenation-induced cardiomyocyte apoptosis.
Inhibition of formyl peptide receptor 1 activity suppresses tumorigenicity in vivo and attenuates the invasion and migration of lung adenocarcinoma cells under hypoxic conditions in vitro.
Effects of the linoleic acid/docosahexaenoic acid ratio and concentration inducing autophagy in Raw264.7 cells against Staphylococcus aureus.
Hyperbaric oxygen treatment mitigates liver damage in mice with noise exposure.
RIP1 promotes proliferation through G2/M checkpoint progression and mediates cisplatin-induced apoptosis and necroptosis in human ovarian cancer cells.
Curcumin inhibits the growth of triple-negative breast cancer cells by silencing EZH2 and restoring DLC1 expression.
Cytisine attenuates bone loss of ovariectomy mouse by preventing RANKL-induced osteoclastogenesis.
Pretreatment with the ALDH2 activator Alda‑1 protects rat livers from ischemia/reperfusion injury by inducing autophagy.
Huoxuezhitong capsule ameliorates MIA-induced osteoarthritis of rats through suppressing PI3K/ Akt/ NF-κB pathway.
GALNT2 regulates ANGPTL3 cleavage in cells and in vivo of mice.
RNA N6-methyladenosine reader IGF2BP3 regulates cell cycle and angiogenesis in colon cancer.
Ability of Post-treatment Glycyrrhizic Acid to Mitigate Cerebral Ischemia/Reperfusion Injury in Diabetic Mice.
4-Acetylantroquinonol B Inhibits Osteoclastogenesis by Inhibiting the Autophagy Pathway in a Simulated Microgravity Model.
WITHDRAWN: Resveratrol partially prevents learning and memory deficits in rats exposed to gaseous formaldehyde.
Aberrant BMP2 Signaling in Patients Diagnosed with Osteoporosis.
Cellular uptake of extracellular nucleosomes induces innate immune responses by binding and activating cGMP-AMP synthase (cGAS).
MG53 Protects hUC-MSCs against Inflammatory Damage and Synergistically Enhances Their Efficacy in Neuroinflammation Injured Brain through Inhibiting NLRP3/Caspase-1/IL-1β Axis.
NGF receptors and PI3K/AKT pathway involved in glucose fluctuation-induced damage to neurons and α-lipoic acid treatment.
Rapamycin Promotes Cardiomyocyte Differentiation of Human Induced Pluripotent Stem Cells in a Stage-Dependent Manner.
MicroRNA-128-1-5p attenuates myocardial ischemia/reperfusion injury by suppressing Gadd45g-mediated apoptotic signaling.
Amino Acids Regulate Cisplatin Insensitivity in Neuroblastoma.
Clusterin contributes to hepatitis C virus-related hepatocellular carcinoma by regulating autophagy.
Neuronostatin Promotion Soluble Aβ1-42 Oligomers: Induced Dysfunctional Brain Glucose Metabolism in Mice.
Inhibition of TBK1 by amlexanox attenuates paraquat-induced acute lung injury.
miR-21a in exosomes from Lewis lung carcinoma cells accelerates tumor growth through targeting PDCD4 to enhance expansion of myeloid-derived suppressor cells.
ROS-mediated PERK-eIF2α-ATF4 pathway plays an important role in arsenite-induced L-02 cells apoptosis via regulating CHOP-DR5 signaling.
Protective effects of isorhamnetin on pulmonary arterial hypertension: in vivo and in vitro studies.
Melatonin synergizes BRAF-targeting agent dabrafenib for the treatment of anaplastic thyroid cancer by inhibiting AKT/hTERT signalling.
Effect of autophagy on irradiation‑induced damage in osteoblast‑like MC3T3‑E1 cells.
STAT3-PTTG11 abrogation inhibits proliferation and induces apoptosis in malignant glioma cells.
SLC25A10 performs an oncogenic role in human osteosarcoma.
Involvement of p53 Acetylation in Growth Suppression of Cutaneous T-Cell Lymphomas Induced by HDAC Inhibition.
DUSP5 (dual-specificity protein phosphatase 5) suppresses BCG-induced autophagy via ERK 1/2 signaling pathway.
N-Ethyl-2-Pyrrolidinone-Substituted Flavan-3-Ols with Anti-inflammatory Activity in Lipopolysaccharide-Stimulated Macrophages Are Storage-Related Marker Compounds for Green Tea.
Regulatory coupling between long noncoding RNAs and senescence in irradiated microglia.
Novel mechanisms underlying anti-polycystic ovary like syndrome effects of electroacupuncture in rats: suppressing SREBP1 to mitigate insulin resistance, mitochondrial dysfunction and oxidative stress.
Impaired mitochondrial medium-chain fatty acid oxidation drives periportal macrovesicular steatosis in sirtuin-5 knockout mice.
HOTAIR maintains the stemness of ovarian cancer stem cells via the miR-206/TBX3 axis.
Hepatoprotective effects of Di Wu Yang Gan: A medicinal food against CCl(4)-induced hepatotoxicity in vivo and in vitro.
Protective effects of pterostilbene against hepatic damage, redox imbalance, mitochondrial dysfunction, and endoplasmic reticulum stress in weanling piglets.
Nrf2 activation protects auditory hair cells from cisplatin-induced ototoxicity independent on mitochondrial ROS production.
Effect of Combined Sorafenib/Cisplatinum Treatment on the Autophagy and Proliferation of Hepatocellular Carcinoma hepG2 Cells in Vitro.
Treatment with 5-methoxytryptophan attenuates microglia-induced neuroinflammation in spinal cord trauma.
Echinacea polysaccharide alleviates LPS-induced lung injury via inhibiting inflammation, apoptosis and activation of the TLR4/NF-κB signal pathway.
Panax notoginseng saponin R1 modulates TNF-α/NF-κB signaling and attenuates allergic airway inflammation in asthma.
LMCD1 antisense RNA 1 (LMCD1-AS1) potentiates thyroid cancer cell growth and stemness via a positive feedback loop of LMCD1-AS1/miR-1287-5p/GLI2.
PKCβ/NF-κB pathway in diabetic atrial remodeling.
Induction of SPARC on Oxidative Stress, Inflammatory Phenotype Transformation, and Apoptosis of Human Brain Smooth Muscle Cells Via TGF-β1-NOX4 Pathway.
Lamin B1 deficiency promotes malignancy and predicts poor prognosis in gastric cancer.
MicroRNA-145 suppresses osteogenic differentiation of human jaw bone marrow mesenchymal stem cells partially via targeting semaphorin 3A.
HIF-1α ameliorates tubular injury in diabetic nephropathy via HO-1-mediated control of mitochondrial dynamics.
miR-124-3p increases in high glucose induced osteocyte-derived exosomes and regulates galectin-3 expression: A possible mechanism in bone remodeling alteration in diabetic periodontitis.
Pharmacological Effects of Fasudil on Flap Survival in a Rodent Model.
Exosomes derived from smooth muscle cells ameliorate diabetes-induced erectile dysfunction by inhibiting fibrosis and modulating the NO/cGMP pathway.
Endoplasmic reticulum stress remodels alveolar bone formation after tooth extraction.
Downregulation of HDAC1 suppresses media degeneration by inhibiting the migration and phenotypic switch of aortic vascular smooth muscle cells in aortic dissection.
Insulin Promotes Corneal Nerve Repair and Wound Healing in Type 1 Diabetic Mice by Enhancing Wnt/β-Catenin Signaling.
Genkwadaphnin inhibits growth and invasion in hepatocellular carcinoma by blocking DHCR24-mediated cholesterol biosynthesis and lipid rafts formation.
Deficiency of pseudogene UPAT leads to hepatocellular carcinoma progression and forms a positive feedback loop with ZEB1.
miRNA-122-5p stimulates the proliferation and DNA synthesis and inhibits the early apoptosis of human spermatogonial stem cells by targeting CBL and competing with lncRNA CASC7.
Liver Expression of IGF2 and Related Proteins in ZBED6 Gene-Edited Pig by RNA-Seq.
miR-100-3p inhibits the adipogenic differentiation of hMSCs by targeting PIK3R1 via the PI3K/AKT signaling pathway.
HMGB1 mediates homocysteine-induced endothelial cells pyroptosis via cathepsin V-dependent pathway.
Polysaccharides from Armillariella tabescens mycelia ameliorate insulin resistance in type 2 diabetic mice.
Vernonia patula (Dryand.) Merr. and Leucas chinensis (Retz.) R. Brown exert anti-inflammatory activities and relieve oxidative stress via Nrf2 activation.
Lysine acetylation of F-actin decreases tropomyosin-based inhibition of actomyosin activity.
Oral recombinant methioninase increases TRAIL receptor-2 expression to regress pancreatic cancer in combination with agonist tigatuzumab in an orthotopic mouse model.
Artesunate induces autophagy dependent apoptosis through upregulating ROS and activating AMPK-mTOR-ULK1 axis in human bladder cancer cells.
Differential distribution and potential regulatory roles of estrogen receptor 2a and 2b in the pituitary of ricefield eel Monopterus albus.
Norcantharidin protects against renal interstitial fibrosis by suppressing TWEAK-mediated Smad3 phosphorylation.
Anti-neuroinflammatory effect of 3,4-dihydroxybenzaldehyde in ischemic stroke.
The B7-H4 gene induces immune escape partly via upregulating the PD-1/Stat3 pathway in non-small cell lung cancer.
Protective effect of Berberine on reproductive function and spermatogenesis in diabetic rats via inhibition of ROS/JAK2/NFκB pathway.
Cannabinoid receptor 2 activation alleviates septic lung injury by promoting autophagy via inhibition of inflammatory mediator release.
miR-362 knock-down promotes proliferation and inhibits apoptosis in porcine immature Sertoli cells by targeting the RMI1 gene.
miR‑95 promotes osteosarcoma growth by targeting SCNN1A.
Establishment and characterization of an immortalized human chondrocyte cell line.
Characterization of a Novel Interleukin-1 Receptor Antagonist from Sheep (Ovis aries).
Relevance research between the expression of p16(INK4a) , Notch1, and hTERC genes: The development of HPV16-positive cervical cancer.
The role of PSMB5 in sodium arsenite-induced oxidative stress in L-02 cells.
MiR-145-5p alleviates hypoxia/reoxygenation- induced cardiac microvascular endothelial cell injury in coronary heart disease by inhibiting Smad4 expression.
AMPK-mTOR-ULK1 axis activation-dependent autophagy promotes hydroxycamptothecin-induced apoptosis in human bladder cancer cells.
Porcine parvovirus nonstructural protein NS1 activates NF-κB and it involves TLR2 signaling pathway.
Leptin mediates protection of hydrogen sulfide against 6-hydroxydopamine-induced Parkinson's disease: Involving enhancement in Warburg effect.
Expression and distribution of bone morphogenetic protein 4 and its antagonist Noggin in the skin of Kazakh sheep (Ovis aries) with a white and brown coat color.
ROS enhances the cytotoxicity of cisplatin by inducing apoptosis and autophagy in tongue squamous cell carcinoma cells.
Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.
High glucose inhibits vascular endothelial Keap1/Nrf2/ARE signal pathway via downregulation of monomethyltransferase SET8 expression.
Effects of inhalation of sevoflurane at different concentrations on TRPV1 in airways of rats at different developmental stages.
Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype.
LncRNA TROJAN promotes proliferation and resistance to CDK4/6 inhibitor via CDK2 transcriptional activation in ER+ breast cancer.
Overexpression of endogenous lipoic acid synthase attenuates pulmonary fibrosis induced by crystalline silica in mice.
Spinosin Inhibits Aβ(1-42) Production and Aggregation via Activating Nrf2/HO-1 Pathway.
Association analysis of DNA methyltransferases in IgA nephropathy.
Role of PEPT1in the transport of cinnabar in Caco-2 cells.
Ginsenoside protects against AKI via activation of HIF‑1α and VEGF‑A in the kidney‑brain axis.
MTFP1 overexpression promotes the growth of oral squamous cell carcinoma by inducing ROS production.
Soluble Uric Acid Promotes Atherosclerosis via AMPK (AMP-Activated Protein Kinase)-Mediated Inflammation.
Sodium butyrate inhibits migration and induces AMPK-mTOR pathway-dependent autophagy and ROS-mediated apoptosis via the miR-139-5p/Bmi-1 axis in human bladder cancer cells.
Guizhi Decoction () Inhibits Cholinergic Transdifferentiation by Regulating Imbalance of NGF and LIF in Salt-Sensitive Hypertensive Heart Failure Rats.
Hyperthermic intraperitoneal chemotherapy with recombinant mutant human TNF-α and raltitrexed in mice with colorectal-peritoneal carcinomatosis.
Prenatal hypoxia inhibited propionate-evoked BK channels of mesenteric artery smooth muscle cells in offspring.
LncRNA MALAT1 knockdown inhibits cell migration and invasion by suppressing autophagy through miR-384/GOLM1 axis in glioma.
The Immunomodulatory Effects and Mechanisms of Tim-3 Action in the Early Stage of Mice with Severe Acute Pancreatitis.
Protein microarray analysis of cytokine expression changes in distal stumps after sciatic nerve transection.
CADM1 inhibits ovarian cancer cell proliferation and migration by potentially regulating the PI3K/Akt/mTOR pathway.
Metformin alleviates breast cancer through targeting high-mobility group AT-hook 2.
circFOXM1 promotes proliferation of non-small cell lung carcinoma cells by acting as a ceRNA to upregulate FAM83D.
Role of autophagy and apoptosis in atrophic epithelium in oral submucous fibrosis.
The mechanism and role of intracellular α-ketoglutarate reduction in hepatic stellate cell activation.
Connective tissue growth factor as an unfavorable prognostic marker promotes the proliferation, migration, and invasion of gliomas.
The Late Domain of Prototype Foamy Virus Gag Facilitates Autophagic Clearance of Stress Granules by Promoting Amphisome Formation.
Critical role of toll-like receptor 4 (TLR4) in ricin toxin-induced inflammatory responses in macrophages.
Monocyte-derived extracellular vesicles upon treated by palmitate promote endothelial migration and monocytes attachment to endothelial cells.
Transgelin-2 contributes to proliferation and progression of hepatocellular carcinoma via regulating Annexin A2.
Effect of NF-κB signal pathway on mucus secretion induced by atmospheric PM(2.5) in asthmatic rats.
Club cell 10-kDa protein (CC10) inhibits cPLA2/COX2 pathway to alleviate RSV-induced airway inflammation and AHR.
Microglia polarization of hippocampus is involved in the mechanism of Apelin-13 ameliorating chronic water immersion restraint stress-induced depression-like behavior in rats.
Dihydromethysticin, a natural molecule from Kava, suppresses the growth of colorectal cancer via the NLRC3/PI3K pathway.
Obesity induces preadipocyte CD36 expression promoting inflammation via the disruption of lysosomal calcium homeostasis and lysosome function.
Effects of cisplatin on the proliferation, invasion and apoptosis of breast cancer cells following β‑catenin silencing.
Compositional characterization of Pyrus ussuriensis Maxim and their antioxidant activities and induction of apoptosis in Bel-7402 cell.
Alda-1, an Aldehyde Dehydrogenase 2 Agonist, Improves Cutaneous Wound Healing by Activating Epidermal Keratinocytes via Akt/GSK-3β/β-Catenin Pathway.
Protein Phosphatase 2A Inhibiting β-Catenin Phosphorylation Contributes Critically to the Anti-renal Interstitial Fibrotic Effect of Norcantharidin.
Neuroprotective effects of notoginsenoside R1 by upregulating Trx-1 on acrylamide-induced neurotoxicity in PC12.
Hispidulin Inhibits Neuroinflammation in Lipopolysaccharide-Activated BV2 Microglia and Attenuates the Activation of Akt, NF-κB, and STAT3 Pathway.
CAFs-derived MFAP5 promotes bladder cancer malignant behavior through NOTCH2/HEY1 signaling.
Effect of STAT3 mediated epigenetic regulation in pre-eclampsia: an analysis of trial data.
Triiodothyronine potentiates angiogenesis-related factor expression through PI3K/AKT signaling pathway in human osteoarthritic osteoblasts.
Correction of Bcl-x splicing improves responses to imatinib in chronic myeloid leukaemia cells and mouse models.
Tubeimoside I improves survival of mice in sepsis by inhibiting inducible nitric oxide synthase expression.
CD4(+) T cells and TGFβ1/MAPK signal pathway involved in the valvular hyperblastosis and fibrosis in patients with rheumatic heart disease.
Beneficial Effects of Theta-Burst Transcranial Magnetic Stimulation on Stroke Injury via Improving Neuronal Microenvironment and Mitochondrial Integrity.
Pseudolaric acid B induces mitotic arrest and apoptosis in both imatinib-sensitive and -resistant chronic myeloid leukaemia cells.
lncRNA MIRF Promotes Cardiac Apoptosis through the miR-26a-Bak1 Axis.
Paeoniflorin-6'-O-benzene sulfonate down-regulates CXCR4-Gβγ-PI3K/AKT mediated migration in fibroblast-like synoviocytes of rheumatoid arthritis by inhibiting GRK2 translocation.
Deletion of the Impg2 gene causes the degeneration of rod and cone cells in mice.
The RBP1-CKAP4 axis activates oncogenic autophagy and promotes cancer progression in oral squamous cell carcinoma.
A Gold(I) Complex Containing an Oleanolic Acid Derivative as a Potential Anti-Ovarian-Cancer Agent by Inhibiting TrxR and Activating ROS-Mediated ERS.
YBX1 mediates autophagy by targeting p110β and decreasing the sensitivity to cisplatin in NSCLC.
Role of mitochondrial acyl-CoA dehydrogenases in the metabolism of dicarboxylic fatty acids.
Drp1, a potential therapeutic target for Parkinson's disease, is involved in olfactory bulb pathological alteration in the Rotenone-induced rat model.
LncRNA-H19 induces hepatic stellate cell activation via upregulating alcohol dehydrogenase III-mediated retinoic acid signals.
Network Pharmacology and Bioactive Equivalence Assessment Integrated Strategy Driven Q-markers Discovery for Da-Cheng-Qi Decoction to Attenuate Intestinal Obstruction.
The up-regulation of NDRG1 by HIF counteracts the cancer-promoting effect of HIF in VHL-deficient clear cell renal cell carcinoma.
Pycnogenol achieves neuroprotective effects in rats with spinal cord injury by stabilizing the mitochondrial membrane potential.
Expression of lncRNA-HOTAIR in the serum of patients with lymph node metastasis of papillary thyroid carcinoma and its impact.
Leucine-rich α-2-glycoprotein-1 promotes diabetic corneal epithelial wound healing and nerve regeneration via regulation of matrix metalloproteinases.
Fingolimod (FTY720) improves postoperative cognitive dysfunction in mice subjected to D-galactose-induced aging.
Resveratrol slows the tumourigenesis of pancreatic cancer by inhibiting NFκB activation.
The Establishment and Application Studies on Precise Lysosome pH Indicator Based on Self-Decomposable Nanoparticles.
PD-L1 promotes tumor growth and progression by activating WIP and β-catenin signaling pathways and predicts poor prognosis in lung cancer.
Elevated expression of minichromosome maintenance 3 indicates poor outcomes and promotes G1/S cell cycle progression, proliferation, migration and invasion in colorectal cancer.
miR-5089-5p suppresses castration-resistant prostate cancer resistance to enzalutamide and metastasis via miR-5089-5p/SPINK1/ MAPK/MMP9 signaling.
Nintedanib Reduces Neutrophil Chemotaxis via Activating GRK2 in Bleomycin-Induced Pulmonary Fibrosis.
Myeloid cells protect intestinal epithelial barrier integrity through the angiogenin/plexin-B2 axis.
Euscaphic acid and Tormentic acid protect vascular endothelial cells against hypoxia-induced apoptosis via PI3K/AKT or ERK 1/2 signaling pathway.
Antitumor activity of celastrol by inhibition of proliferation, invasion, and migration in cholangiocarcinoma via PTEN/PI3K/Akt pathway.
PRRX1-induced epithelial-to-mesenchymal transition in salivary adenoid cystic carcinoma activates the metabolic reprogramming of free fatty acids to promote invasion and metastasis.
α-Ketoglutarate Modulates Macrophage Polarization Through Regulation of PPARγ Transcription and mTORC1/p70S6K Pathway to Ameliorate ALI/ARDS.
miRNA‑342 suppresses renal interstitial fibrosis in diabetic nephropathy by targeting SOX6.
Insulin secretion impairment induced by rosuvastatin partly though autophagy in INS-1E cells.
MiR-22 restrains proliferation of rheumatoid arthritis by targeting IL6R and may be concerned with the suppression of NF-κB pathway.
Scavenger receptor A impairs interferon response to HBV infection by limiting TRAF3 ubiquitination through recruiting OTUB1.
Fluoride induced mitochondrial impairment and PINK1-mediated mitophagy in Leydig cells of mice: In vivo and in vitro studies.
NRSN2 promotes breast cancer metastasis by activating PI3K/AKT/mTOR and NF-κB signaling pathways.
LINC00365-SCGB2A1 axis inhibits the viability of breast cancer through targeting NF-κB signaling.
MicroRNA-150 functions as a tumor suppressor and sensitizes osteosarcoma to doxorubicin-induced apoptosis by targeting RUNX2.
Matrine suppresses breast cancer metastasis by targeting ITGB1 and inhibiting epithelial-to-mesenchymal transition.
Effect of stromal cell-derived factor-1/CXCR4 axis in neural stem cell transplantation for Parkinson's disease.
Perilla oil regulates intestinal microbiota and alleviates insulin resistance through the PI3K/AKT signaling pathway in type-2 diabetic KKAy mice.
Involvement of proliferative and apoptotic factors in the development of hindgut in rat fetuses with ethylenethiourea-induced anorectal malformations.
Naturally-derived diterpenoid sphaeropsidin C as an activator of Nrf2/ARE pathway and its potential capability of relieving intracellular oxidative stress in human lung epithelial cells.
Human umbilical cord blood mononuclear cells protect against renal tubulointerstitial fibrosis in cisplatin-treated rats.
Deoxycholic Acid Upregulates the Reprogramming Factors KFL4 and OCT4 Through the IL-6/STAT3 Pathway in Esophageal Adenocarcinoma Cells.
Odor-mediated contextual learning induced memory consolidation and hippocampus development in neonate rat.
Aspirin enhances the sensitivity of colon cancer cells to cisplatin by abrogating the binding of NF-κB to the COX-2 promoter.
Protective effects of Salidroside on spermatogenesis in streptozotocin induced type-1 diabetic male mice by inhibiting oxidative stress mediated blood-testis barrier damage.
Suppression of Notch Signaling Stimulates Progesterone Synthesis by Enhancing the Expression of NR5A2 and NR2F2 in Porcine Granulosa Cells.
Romo1 is involved in the immune response of glioblastoma by regulating the function of macrophages.
Angiotensin II-Induced vascular remodeling and hypertension involves cathepsin L/V- MEK/ERK mediated mechanism.
The testis-specific gene 1700102P08Rik is essential for male fertility.
Asiaticoside nitric oxide gel accelerates diabetic cutaneous ulcers healing by activating Wnt/β-catenin signaling pathway.
FLI1 promotes protein translation via the transcriptional regulation of MKNK1 expression.
Screening for reproductive biomarkers in Bactrian camel via iTRAQ analysis of proteomes.
Resveratrol Downregulates STAT3 Expression and Astrocyte Activation in Primary Astrocyte Cultures of Rat.
Dendrobium Alkaloids Promote Neural Function After Cerebral Ischemia-Reperfusion Injury Through Inhibiting Pyroptosis Induced Neuronal Death in both In Vivo and In Vitro Models.
Study of the protective effect on damaged intestinal epithelial cells of rat multilineage-differentiating stress-enduring (Muse) cells.
Programmed cell death protein 1 promotes hepatitis B virus transmission through the regulation of ERK1/2-mediated trophoblasts differentiation.
Anti-insulin resistance effects of salidroside through mitochondrial quality control.
Inhibition of PFKFB3 suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss.
Post-production modifications of murine mesenchymal stem cell (mMSC) derived extracellular vesicles (EVs) and impact on their cellular interaction.
CMIP promotes Herceptin resistance of HER2 positive gastric cancer cells.
Inhibition of calcineurin/NFATc4 signaling attenuates ventilator‑induced lung injury.
Effects of dexmedetomidine on oxidative stress and inflammatory response in lungs during mechanical ventilation in COPD rats.
Elevated levels of arachidonic acid metabolites in follicular fluid of PCOS patients.
Isorhamnetin attenuates Streptococcus suis virulence by inhibiting the inflammatory response.
Targeting the miR-122/PKM2 autophagy axis relieves arsenic stress.
A20 targets PFKL and glycolysis to inhibit the progression of hepatocellular carcinoma.
Colorectal cancer-derived exosomal miR-106b-3p promotes metastasis by down-regulating DLC-1 expression.
Minicircle DNA vector expressing interferon-lambda-3 inhibits hepatitis B virus replication and expression in hepatocyte-derived cell line.
A tropomyosin-like Meretrix meretrix Linnaeus polypeptide inhibits the proliferation and metastasis of glioma cells via microtubule polymerization and FAK/Akt/MMPs signaling.
Transactivation of miR-202-5p by Steroidogenic Factor 1 (SF1) Induces Apoptosis in Goat Granulosa Cells by Targeting TGFβR2.
GPAT3 deficiency alleviates insulin resistance and hepatic steatosis in a mouse model of severe congenital generalized lipodystrophy.
Protection of diabetes-induced kidney injury by phosphocreatine via the regulation of ERK/Nrf2/HO-1 signaling pathway.
Fine-tuning of the respiratory complexes stability and supercomplexes assembly in cells defective of complex III.
Honokiol inhibits the growth of SKBR3 cells.
Geniposide in Gardenia jasminoides var. radicans Makino modulates blood pressure via inhibiting WNK pathway mediated by the estrogen receptors.
MicroRNA-217 ameliorates inflammatory damage of endothelial cells induced by oxidized LDL by targeting EGR1.
Alprostadil attenuates LPS-induced cardiomyocyte injury by inhibiting the Wnt5a/JNK/NF-κB pathway.
Exogenous CGRP Regulates Apoptosis and Autophagy to Alleviate Traumatic Brain Injury Through Akt/mTOR Signalling Pathway.
Acylglycerol kinase promotes the stemness of nasopharyngeal carcinoma cells by promoting β-catenin translocation to the nucleus through activating PI3K/Akt pathway.
Myeloid-derived suppressor cells promote epithelial ovarian cancer cell stemness by inducing the CSF2/p-STAT3 signalling pathway.
Co-delivery of paclitaxel and anti-VEGF siRNA by tripeptide lipid nanoparticle to enhance the anti-tumor activity for lung cancer therapy.
Poldip2 mediates blood-brain barrier disruption and cerebral edema by inducing AQP4 polarity loss in mouse bacterial meningitis model.
Inhibition of miRNA-29a regulates intestinal barrier function in diarrhea-predominant irritable bowel syndrome by upregulating ZO-1 and CLDN1.
Baicalin reversal of DNA hypermethylation-associated Klotho suppression ameliorates renal injury in type 1 diabetic mouse model.
Functional Food XingJiuTang Attenuates Alcohol-Induced Liver Injury by Regulating SIRT1/Nrf-2 Signaling Pathway.
TLR4 inhibition ameliorates mesencephalic substantia nigra injury in neonatal rats exposed to lipopolysaccharide via regulation of neuro-immunity.
Saikosaponin-d impedes hippocampal neurogenesis and causes cognitive deficits by inhibiting the survival of neural stem/progenitor cells via neurotrophin receptor signaling in mice.
Transforming growth factor beta type 1 (TGF-β) and hypoxia-inducible factor 1 (HIF-1) transcription complex as master regulators of the immunosuppressive protein galectin-9 expression in human cancer and embryonic cells.
MicroRNA-410-3p Binds to TLR2 and Alleviates Myocardial Mitochondrial Dysfunction and Chemokine Production in LPS-Induced Sepsis.
Curcumin protects rat hippocampal neurons against pseudorabies virus by regulating the BDNF/TrkB pathway.
Multi-walled carbon nanotubes decrease neuronal NO synthase in 3D brain organoids.
Decreased Expression of the Host Long-Noncoding RNA-GM Facilitates Viral Escape by Inhibiting the Kinase activity TBK1 via S-glutathionylation.
Initiation of PI3K/AKT pathway by IGF-1 decreases spinal cord injury-induced endothelial apoptosis and microvascular damage.
Discovery of potent small molecule PROTACs targeting mutant EGFR.
An autoregulatory feedback loop of miR-21/VMP1 is responsible for the abnormal expression of miR-21 in colorectal cancer cells.
Indoxyl sulfate promotes osteogenic differentiation of vascular smooth muscle cells by miR-155-5p-dependent downregulation of matrix Gla protein via ROS/NF-κB signaling.
Berberine alleviates cisplatin-induced acute kidney injury by regulating mitophagy via PINK 1/Parkin pathway.
Minocycline prevents the depressive-like behavior through inhibiting the release of HMGB1 from microglia and neurons.
Melatonin Ameliorates Renal Fibrosis Through the Inhibition of NF-κB and TGF-β1/Smad3 Pathways in db/db Diabetic Mice.
LncRNA XIST promotes chemoresistance of breast cancer cells to doxorubicin by sponging miR-200c-3p to upregulate ANLN.
Role of the Nucleotide-Binding Domain-Like Receptor Protein 3 Inflammasome in the Endothelial Dysfunction of Early Sepsis.
Integrin-α9 and Its Corresponding Ligands Play Regulatory Roles in Chronic Periodontitis.
The metabolic changes in the hippocampus of an atherosclerotic rat model and the regulation of aerobic training.
USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylation.
PRDM16 orchestrates angiogenesis via neural differentiation in the developing brain.
MiR-34a affects G2 arrest in prostate cancer PC3 cells via Wnt pathway and inhibits cell growth and migration.
Vitamin D3 protects articular cartilage by inhibiting the Wnt/β-catenin signaling pathway.
Graphene oxide size-dependently altered lipid profiles in THP-1 macrophages.
Identification of EMT-related high-risk stage II colorectal cancer and characterisation of metastasis-related genes.
Activation of the Hedgehog Pathway Promotes Recovery of Neurological Function After Traumatic Brain Injury by Protecting the Neurovascular Unit.
A mutation found in esophageal cancer alters integrin β4 mRNA splicing.
BCCIPβ facilitates p53 ubiquitination via binding with E6 protein in high-risk HPV positive head and neck squamous cell carcinoma.
FB-15 inhibits MGC-803 cells growth by regulating energy metabolism.
BVES downregulation in non-syndromic tetralogy of fallot is associated with ventricular outflow tract stenosis.
ZEB1-Mediated Transcriptional Upregulation of circWWC3 Promotes Breast Cancer Progression through Activating Ras Signaling Pathway.
Computational repositioning of dimethyl fumarate for treating alcoholic liver disease.
Silychristin A activates Nrf2-HO-1/SOD2 pathway to reduce apoptosis and improve GLP-1 production through upregulation of estrogen receptor α in GLUTag cells.
Metformin ameliorates cardiac conduction delay by regulating microRNA-1 in mice.
Antagomirs targeting miR-142-5p attenuate pilocarpine-induced status epilepticus in mice.
Sulforaphane enhances the cisplatin sensitivity through regulating DNA repair and accumulation of intracellular cisplatin in ovarian cancer cells.
HIF-1α-upregulated lncRNA-H19 regulates lipid droplet metabolism through the AMPKα pathway in hepatic stellate cells.
Progesterone promotes endothelial nitric oxide synthase expression through enhancing nuclear progesterone receptor-SP-1 formation.
A multi-scale systems pharmacology approach uncovers the anti-cancer molecular mechanism of Ixabepilone.
Pyrazinamide alleviates rifampin-induced steatohepatitis in mice by regulating the activities of cholesterol-activated 7α-hydroxylase and lipoprotein lipase.
Exogenous hydrogen sulfide inhibits human melanoma cell development via suppression of the PI3K/AKT/ mTOR pathway.
Responses of intestinal morphology and function in offspring to heat stress in primiparous sows during late gestation.
Hydrogen sulfide inhibits cigarette smoke-induced inflammation and injury in alveolar epithelial cells by suppressing PHD2/HIF-1α/MAPK signaling pathway.
Lycopene attenuates body weight gain through induction of browning via regulation of peroxisome proliferator-activated receptor γ in high-fat diet-induced obese mice.
Identification of novel variants in the FZD4 gene associated with familial exudative vitreoretinopathy in Chinese families.
High- and low-virulent bovine Pasteurella multocida induced differential NLRP3 inflammasome activation and subsequent IL-1β secretion.
Stromal fibroblast-derived MFAP5 promotes the invasion and migration of breast cancer cells via Notch1/slug signaling.
Decreased basal and stimulated salivary parameters by histopathological lesions and secretory dysfunction of parotid and submandibular glands in rats with type 2 diabetes.
Novel nortriterpenoids with new skeletons and limonoids from the fruits of Evodia rutaecarpa and their bioactivities.
SMAD3/SP1 complex-mediated constitutive active loop between lncRNA PCAT7 and TGF-β signaling promotes prostate cancer bone metastasis.
Paradoxical Pro-inflammatory Responses by Human Macrophages to an Amoebae Host-Adapted Legionella Effector.
Calcium-sensing receptor promotes tumor proliferation and migration in human intrahepatic cholangiocarcinoma by targeting ERK signaling pathway.
Ablation of glutaredoxin 1 promotes pulmonary angiogenesis and alveolar formation in hyperoxia-injured lungs by modifying HIF-1α stability and inhibiting the NF-κB pathway.
An inducible intestinal epithelial cell-specific NHE3 knockout mouse model mimicking congenital sodium diarrhea.
RNA-seq analysis of potential lncRNAs for age-related hearing loss in a mouse model.
CACNA1H downregulation induces skeletal muscle atrophy involving endoplasmic reticulum stress activation and autophagy flux blockade.
MicroRNA-183 regulates lipopolysaccharide-induced oxidative stress of hippocampal neurons by targeting the fibronectin 1 gene.
Asperosaponin VI Injection Enhances Orthodontic Tooth Movement in Rats.
Posterior Neocortex-Specific Regulation of Neuronal Migration by CEP85L Identifies Maternal Centriole-Dependent Activation of CDK5.
Effect of KIF22 on promoting proliferation and migration of gastric cancer cells via MAPK-ERK pathways.
CCL5 derived from tumor-associated macrophages promotes prostate cancer stem cells and metastasis via activating β-catenin/STAT3 signaling.
Histone Deacetylation 10 Alleviates Inflammation After Intracerebral Hemorrhage via the PTPN22/NLRP3 Pathway in Rats.
All-trans-retinal induces autophagic cell death via oxidative stress and the endoplasmic reticulum stress pathway in human retinal pigment epithelial cells.
Targeting β2 subunit of Na(+)/K(+)-ATPase induces glioblastoma cell apoptosis through elevation of intracellular Ca(2).
p66Shc Contributes to Liver Fibrosis through the Regulation of Mitochondrial Reactive Oxygen Species.
LncRNA-MTA2TR functions as a promoter in pancreatic cancer via driving deacetylation-dependent accumulation of HIF-1α.
Targeting mitochondrial dynamics by regulating Mfn2 for therapeutic intervention in diabetic cardiomyopathy.
STAT3 Contributes To Oncolytic Newcastle Disease Virus-Induced Immunogenic Cell Death in Melanoma Cells.
Antitumor Effects of Berberine on Gliomas via Inactivation of Caspase-1-Mediated IL-1β and IL-18 Release.
PNS-R1 inhibits Dex-induced bronchial epithelial cells apoptosis in asthma through mitochondrial apoptotic pathway.
MiR-24-3p Inhibits the Progression of Pancreatic Ductal Adenocarcinoma Through LAMB3 Downregulation.
The Binding of PD-L1 and Akt Facilitates Glioma Cell Invasion Upon Starvation via Akt/Autophagy/F-Actin Signaling.
Critical role of Tim-3 mediated autophagy in chronic stress induced immunosuppression.
MTHFD1L-Mediated Redox Homeostasis Promotes Tumor Progression in Tongue Squamous Cell Carcinoma.
Chrysanthemum extract attenuates hepatotoxicity via inhibiting oxidative stress in vivo and in vitro.
Mild hypothermia improves neurological outcome in mice after cardiopulmonary resuscitation through Silent Information Regulator 1-actviated autophagy.
Inhibition of Mitochondrial Complex I Aggravates Folic Acid-Induced Acute Kidney Injury.
Targeting autophagy enhances heat stress-induced apoptosis via the ATP-AMPK-mTOR axis for hepatocellular carcinoma.
SOCS3 control the activity of NF-κB induced by HSP70 via degradation of MyD88-adapter-like protein (Mal) in IPEC-J2 cells.
LncRNA ZFAS1 promotes proliferation and migration and inhibits apoptosis in nasopharyngeal carcinoma via the PI3K/AKT pathway in vitro.
Long non-coding RNA MAGI2-AS3 inhibits breast cancer cell migration and invasion via sponging microRNA-374a.
UHRF1 Promotes Proliferation of Human Adipose-Derived Stem Cells and Suppresses Adipogenesis via Inhibiting Peroxisome Proliferator-Activated Receptor γ.
Mechanisms of Aerobic Exercise Upregulating the Expression of Hippocampal Synaptic Plasticity-Associated Proteins in Diabetic Rats.
Spica Prunellae Extract Enhances Fluorouracil Sensitivity of 5-Fluorouracil-Resistant Human Colon Carcinoma HCT-8/5-FU Cells via TOP2α and miR-494.
Hepatitis B Virus X Protein-Induced RORγ Expression to Promote the Migration and Proliferation of Hepatocellular Carcinoma.
Primary Cilia Blockage Promotes the Malignant Behaviors of Hepatocellular Carcinoma via Induction of Autophagy.
Carnosine Protects Mouse Podocytes from High Glucose Induced Apoptosis through PI3K/AKT and Nrf2 Pathways.
Analysis of Toll-Like Receptors in Human Milk: Detection of Membrane-Bound and Soluble Forms.
Alleviation of Hepatic Ischemia Reperfusion Injury by Oleanolic Acid Pretreating via Reducing HMGB1 Release and Inhibiting Apoptosis and Autophagy.
Atorvastatin Inhibits Breast Cancer Cells by Downregulating PTEN/AKT Pathway via Promoting Ras Homolog Family Member B (RhoB).
Nrf2/Keap1/ARE Signaling Mediated an Antioxidative Protection of Human Placental Mesenchymal Stem Cells of Fetal Origin in Alveolar Epithelial Cells.
Jiawei Foshou San Induces Apoptosis in Ectopic Endometrium Based on Systems Pharmacology, Molecular Docking, and Experimental Evidence.
Jiedu Sangen Decoction Inhibits the Invasion and Metastasis of Colorectal Cancer Cells by Regulating EMT through the Hippo Signaling Pathway.
RAD51 is a potential marker for prognosis and regulates cell proliferation in pancreatic cancer.
Casticin inhibits nasopharyngeal carcinoma growth by targeting phosphoinositide 3-kinase.
SIRT6/HIF-1α axis promotes papillary thyroid cancer progression by inducing epithelial-mesenchymal transition.
TGF-β1 Induces Epithelial-Mesenchymal Transition of Chronic Sinusitis with Nasal Polyps through MicroRNA-21.
Anti-apoptotic effect of the Shh signaling pathway in cigarette smoke extract induced MLE 12 apoptosis.
P11 Loss-of-Function is Associated with Decreased Cell Proliferation and Neurobehavioral Disorders in Mice.
Glycolytic Enzyme PKM2 Mediates Autophagic Activation to Promote Cell Survival in NPM1-Mutated Leukemia.
LncRNA SLCO4A1-AS1 predicts poor prognosis and promotes proliferation and metastasis via the EGFR/MAPK pathway in colorectal cancer.
LncRNA expression profile during autophagy and Malat1 function in macrophages.
NAMPT overexpression alleviates alcohol-induced hepatic steatosis in mice.
Porous Se@SiO(2) nanocomposite promotes migration and osteogenic differentiation of rat bone marrow mesenchymal stem cell to accelerate bone fracture healing in a rat model.
Inhibition of COX2/PGD2-Related Autophagy Is Involved in the Mechanism of Brain Injury in T2DM Rat.
Bone Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote Recovery Following Spinal Cord Injury via Improvement of the Integrity of the Blood-Spinal Cord Barrier.
CITED1 contributes to the progression of papillary thyroid carcinoma via the Wnt/β-catenin signaling pathway.
GPX2 suppression of H(2)O(2) stress regulates cervical cancer metastasis and apoptosis via activation of the β-catenin-WNT pathway.
SIRT6 promotes the Warburg effect of papillary thyroid cancer cell BCPAP through reactive oxygen species.
Prognostic implications and oncogenic roles of MYBL2 protein expression in esophageal squamous-cell carcinoma.
DHT deteriorates the progression of monocrotaline-induced pulmonary arterial hypertension: effects of endogenous and exogenous androgen.
miR-23a-5p inhibits cell proliferation and invasion in pancreatic ductal adenocarcinoma by suppressing ECM1 expression.
Catalpol improves axonal outgrowth and reinnervation of injured sciatic nerve by activating Akt/mTOR pathway and regulating BDNF and PTEN expression.
The IRE1α-XBP1 pathway function in hypoxia-induced pulmonary vascular remodeling, is upregulated by quercetin, inhibits apoptosis and partially reverses the effect of quercetin in PASMCs.
Rutin suppresses FNDC1 expression in bone marrow mesenchymal stem cells to inhibit postmenopausal osteoporosis.
The lncRNA HOXA11-AS regulates Rab3D expression by sponging miR-125a-5p promoting metastasis of osteosarcoma.
High expression of SMARCE1 predicts poor prognosis and promotes cell growth and metastasis in gastric cancer.
Catalpol Exerts a Neuroprotective Effect in the MPTP Mouse Model of Parkinson's Disease.
MARCH5 overexpression contributes to tumor growth and metastasis and associates with poor survival in breast cancer.
AAV-Mig-6 Increase the Efficacy of TAE in VX2 Rabbit Model, Is Associated With JNK Mediated Autophagy.
Up-regulation of EMT-related gene VCAN by NPM1 mutant-driven TGF-β/cPML signalling promotes leukemia cell invasion.
SIRT5 Promotes Hepatocellular Carcinoma Progression by Regulating Mitochondrial Apoptosis.
Involvement of Actin-Regulating Factor Cofilin in the Inclusion Body Formation and RNA Synthesis of Human Parainfluenza Virus Type 3 via Interaction With the Nucleoprotein.
Naringenin Produces Neuroprotection Against LPS-Induced Dopamine Neurotoxicity via the Inhibition of Microglial NLRP3 Inflammasome Activation.
miR-181b-5p May Regulate Muscle Growth in Tilapia by Targeting Myostatin b.
TLR4/NF-κB Signaling Induces GSDMD-Related Pyroptosis in Tubular Cells in Diabetic Kidney Disease.
The Wnt/β-Catenin/LEF1 Pathway Promotes Cell Proliferation at Least in Part Through Direct Upregulation of miR-17-92 Cluster.
Combined melatonin and poricoic acid A inhibits renal fibrosis through modulating the interaction of Smad3 and β-catenin pathway in AKI-to-CKD continuum.
Protective Effects of 18β-Glycyrrhetinic Acid on Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats.
Downregulation of Wnt3 Suppresses Colorectal Cancer Development Through Inhibiting Cell Proliferation and Migration.
The Therapeutic Effects of Treadmill Exercise on Osteoarthritis in Rats by Inhibiting the HDAC3/NF-KappaB Pathway in vivo and in vitro.
Protective mechanism of Taxifolin for chlorpyrifos neurotoxicity in BV2 cells.
Time-dependent C5a and C5aR expression in dental pulp cells following stimulation with LTA and LPS.
Fluorene-9-bisphenol inhibits epithelial-mesenchymal transition of human endometrial cancer Ishikawa cells by repressing TGF-β signaling pathway.
Hydrogen inhalation protects hypoxic-ischemic brain damage by attenuating inflammation and apoptosis in neonatal rats.
Dexamethasone interferes with osteoblasts formation during osteogenesis through altering IGF-1-mediated angiogenesis.
Resveratrol inhibits the invasion and metastasis of colon cancer through reversal of epithelial‑ mesenchymal transition via the AKT/GSK‑3β/Snail signaling pathway.
TAK242 suppresses the TLR4 signaling pathway and ameliorates DCD liver IRI in rats.
Mechanism Underlying the Protective Effect of Selenium on NO-Induced Oxidative Damage in Bovine Mammary Epithelial Cells.
Association between CIRP expression and hypoxic-ischemic brain injury in neonatal rats.
REG4 is an indicator for KRAS mutant lung adenocarcinoma with TTF-1 low expression.
Novel diterpenoid-type activators of the Keap1/Nrf2/ARE signaling pathway and their regulation of redox homeostasis.
Multi-walled carbon nanotubes (MWCNTs) promoted lipid accumulation in THP-1 macrophages through modulation of endoplasmic reticulum (ER) stress.
Targeting Exosomal EBV-LMP1 Transfer and miR-203 Expression via the NF-κB Pathway: The Therapeutic Role of Aspirin in NPC.
Enhancing the retrograde axonal transport by curcumin promotes autophagic flux in N2a/APP695swe cells.
ROS/KRAS/AMPK Signaling Contributes to Gemcitabine-Induced Stem-like Cell Properties in Pancreatic Cancer.
Establishment of an Experimental Intracerebral Haemorrhage Model for Mass Effect Research using a Thermo-sensitive Hydrogel.
Protective effects of 18β-glycyrrhetinic acid on pulmonary arterial hypertension via regulation of Rho A/Rho kinsase pathway.
OPA1 overexpression ameliorates mitochondrial cristae remodeling, mitochondrial dysfunction, and neuronal apoptosis in prion diseases.
Structural Characterization and Antioxidant Activity of Polysaccharides from Athyrium multidentatum (Doll.) Ching in d-Galactose-Induced Aging Mice via PI3K/AKT Pathway.
Long Noncoding RNA FAM225A Promotes Nasopharyngeal Carcinoma Tumorigenesis and Metastasis by Acting as ceRNA to Sponge miR-590-3p/miR-1275 and Upregulate ITGB3.
Age-Associated Dopaminergic Neuron Loss and Midbrain Glia Cell Phenotypic Polarization.
Antinociceptive effect of isoorientin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
Macrophage migration inhibitory factor promotes the invasion and metastasis of oral squamous cell carcinoma through matrix metalloprotein-2/9.
Bromodomain inhibitor jq1 induces cell cycle arrest and apoptosis of glioma stem cells through the VEGF/PI3K/AKT signaling pathway.
Paip1 Indicated Poor Prognosis in Cervical Cancer and Promoted Cervical Carcinogenesis.
Babao Dan induces gastric cancer cell apoptosis via regulating MAPK and NF-κB signaling pathways.
Downregulation of nicotinamide N-methyltransferase inhibits migration and epithelial-mesenchymal transition of esophageal squamous cell carcinoma via Wnt/β-catenin pathway.
Apatinib inhibits glycolysis by suppressing the VEGFR2/AKT1/SOX5/GLUT4 signaling pathway in ovarian cancer cells.
Propofol attenuates TNF-α-induced MMP-9 expression in human cerebral microvascular endothelial cells by inhibiting Ca(2+)/CAMK II/ERK/NF-κB signaling pathway.
A novel long noncoding RNA PGC1β-OT1 regulates adipocyte and osteoblast differentiation through antagonizing miR-148a-3p.
Whole-Exome Sequencing Analysis Identified Novel Mutations in the TSPAN12 Gene in Chinese Families with Familial Exudative Vitreoretinopathy.
Turnover of bile acids in liver, serum and caecal content by high-fat diet feeding affects hepatic steatosis in rats.
CX-F9, a novel RSK2 inhibitor, suppresses cutaneous melanoma cells proliferation and metastasis through regulating autophagy.
Novel ADAM-17 inhibitor ZLDI-8 inhibits the proliferation and metastasis of chemo-resistant non-small-cell lung cancer by reversing Notch and epithelial mesenchymal transition in vitro and in vivo.
RNA-Seq analysis of potential lncRNAs and genes for the anti-renal fibrotic effect of norcantharidin.
Neuroprotective effect of Vanillin on hypoxic-ischemic brain damage in neonatal rats.
Dehydroepiandrosterone alleviates E. Coli O157:H7-induced inflammation by preventing the activation of p38 MAPK and NF-κB pathways in mice peritoneal macrophages.
Oncogenic ADAM28 induces gemcitabine resistance and predicts a poor prognosis in pancreatic cancer.
Adipose tissue-derived omentin-1 attenuates arterial calcification via AMPK/Akt signaling pathway.
ROS-mediated inactivation of the PI3K/AKT pathway is involved in the antigastric cancer effects of thioredoxin reductase-1 inhibitor chaetocin.
Fractionated irradiation of right thorax induces abscopal damage on testes leading to decline in fertility.
HIF-1α contributes to Ang II-induced inflammatory cytokine production in podocytes.
The interference of DEHP in precocious puberty of females mediated by the hypothalamic IGF-1/PI3K/Akt/mTOR signaling pathway.
High metabolic rate and stem cell characteristics of esophageal cancer stem-like cells depend on the Hsp27-AKT-HK2 pathway.
Young Blood Rescues the Cognition of Alzheimer's Model Mice by Restoring the Hippocampal Cholinergic Circuit.
PPAR-δ of orange-spotted grouper exerts antiviral activity against fish virus and regulates interferon signaling and inflammatory factors.
Piperine as a neuroprotective functional component in rats with cerebral ischemic injury.
O‑GlcNAc modification influences endometrial receptivity by promoting endometrial cell proliferation, migration and invasion.
Niban protein regulates apoptosis in HK-2 cells via caspase-dependent pathway.
Cadmium regulates von Willebrand factor and occludin expression in glomerular endothelial cells of mice in a TNF-α-dependent manner.
Wnt1 silencing enhances neurotoxicity induced by paraquat and maneb in SH-SY5Y cells.
Propionate relieves pentylenetetrazol-induced seizures, consequent mitochondrial disruption, neuron necrosis and neurological deficits in mice.
Iron dysregulation in vascular dementia: Focused on the AMPK/autophagy pathway.
Identification of predictors of drug sensitivity using patient-derived models of esophageal squamous cell carcinoma.
Hypertension-associated mitochondrial DNA 4401A>G mutation caused the aberrant processing of tRNAMet, all 8 tRNAs and ND6 mRNA in the light-strand transcript.
Dexmedetomidine inhibits neuronal apoptosis by inducing Sigma-1 receptor signaling in cerebral ischemia-reperfusion injury.
Oroxin B Induces Apoptosis by Down-Regulating MicroRNA-221 Resulting in the Inactivation of the PTEN/PI3K/AKT Pathway in Liver Cancer.
PP2Ac Modulates AMPK-Mediated Induction of Autophagy in Mycobacterium bovis-Infected Macrophages.
Protrudin modulates seizure activity through GABA(A) receptor regulation.
Folic acid delays age-related cognitive decline in senescence-accelerated mouse prone 8: alleviating telomere attrition as a potential mechanism.
Dose-Dependent Effects of Triclocarban Exposure on Lipid Homeostasis in Rats.
Inhibition of Bcl-2 Synergistically Enhances the Antileukemic Activity of Midostaurin and Gilteritinib in Preclinical Models of FLT3-Mutated Acute Myeloid Leukemia.
Chitosan Ameliorates DSS-Induced Ulcerative Colitis Mice by Enhancing Intestinal Barrier Function and Improving Microflora.
Circ-ASH2L promotes tumor progression by sponging miR-34a to regulate Notch1 in pancreatic ductal adenocarcinoma.
Protective effects of Clec11a in islets against lipotoxicity via modulation of proliferation and lipid metabolism in mice.
Melatonin protects against COPD by attenuating apoptosis and endoplasmic reticulum stress via upregulating SIRT1 expression in rats.
Functional analysis of the CXCR1a gene response to SGIV viral infection in grouper.
A novel tumor suppressor SPINK5 targets Wnt/β-catenin signaling pathway in esophageal cancer.
Microglial LOX-1/MAPKs/NF-κB positive loop promotes the vicious cycle of neuroinflammation and neural injury.
Activation of Nrf2 signaling by Icariin protects against 6-OHDA-induced neurotoxicity.
Circular RNA cMras inhibits lung adenocarcinoma progression via modulating miR-567/PTPRG regulatory pathway.
Eutopic endometrium from patients with endometriosis modulates the expression of CD36 and SIRP-α in peritoneal macrophages.
Induced Pluripotent Stem Cells Regulate Triggering Receptor Expressed on Myeloid Cell-1 Expression and the p38 Mitogen-Activated Protein Kinase Pathway in Endotoxin-Induced Acute Lung Injury.
HepaCAM Regulates Warburg Effect of Renal Cell Carcinoma via HIF-1α/NF-κB Signaling Pathway.
Kallikrein 12 Regulates Innate Resistance of Murine Macrophages against Mycobacterium bovis Infection by Modulating Autophagy and Apoptosis.
Predictable chronic mild stress promotes recovery from LPS-induced depression.
HMGB1 contributes to SASH1 methylation to attenuate astrocyte adhesion.
Nilotinib: A Tyrosine Kinase Inhibitor Mediates Resistance to Intracellular Mycobacterium Via Regulating Autophagy.
Glucose metabolic alterations in hippocampus of diabetes mellitus rats and the regulation of aerobic exercise.
Efficient Production of Human Norovirus-Specific IgY in Egg Yolks by Vaccination of Hens with a Recombinant Vesicular Stomatitis Virus Expressing VP1 Protein.
Neuroprotective Effect of Swertiamain on Cerebral Ischemia/Reperfusion Injury by Inducing the Nrf2 Protective Pathway.
Role of OXCT1 in ovine adipose and preadipocyte differentiation.
Quantitative proteomic profiling of tumor-associated vascular endothelial cells in colorectal cancer.
Repurposing of omeprazole for oligodendrocyte differentiation and remyelination.
Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice.
An isopentenyl-substituted flavonoid norartocarpin activates Nrf2 signalling pathway and prevents oxidative insults in human lung epithelial cells.
NS38 is required for aquareovirus replication via interaction with viral core proteins and host eIF3A.
CSE1L participates in regulating cell mitosis in human seminoma.
The endogenous retrovirus-derived long noncoding RNA TROJAN promotes triple-negative breast cancer progression via ZMYND8 degradation.
Regulation of Neurotransmitter Release by Amyloid Precursor Protein Through Synapsin Phosphorylation.
MicroRNA‑223 promotes osteoblast differentiation of MC3T3‑E1 cells by targeting histone deacetylase 2.
Wnt7a predicts poor prognosis, and contributes to growth and metastasis in tongue squamous cell carcinoma.
LncRNA EPB41L4A-AS1 regulates glycolysis and glutaminolysis by mediating nucleolar translocation of HDAC2.
The selective HDAC6 inhibitor Nexturastat A induces apoptosis, overcomes drug resistance and inhibits tumor growth in multiple myeloma.
iTRAQ-based quantitative proteomics reveals the neuroprotection of rhubarb in experimental intracerebral hemorrhage.
MicroRNA-596 acts as a tumor suppressor in gastric cancer and is upregulated by promotor demethylation.
Hypoxic BMSC-derived exosomal miRNAs promote metastasis of lung cancer cells via STAT3-induced EMT.
Sericin Nerve Guidance Conduit Delivering Therapeutically Repurposed Clobetasol for Functional and Structural Regeneration of Transected Peripheral Nerves.
The methionine salvage pathway-involving ADI1 inhibits hepatoma growth by epigenetically altering genes expression via elevating S-adenosylmethionine.
S-1-Propenylcysteine augments BACH1 degradation and heme oxygenase 1 expression in a nitric oxide-dependent manner in endothelial cells.
The role of autophagy in the overexpression of MUC5AC in patients with chronic rhinosinusitis.
Acid sphingomyelinase mediates the noise-induced liver disorder in mice.
Upregulated histamine receptor H3 promotes tumor growth and metastasis in hepatocellular carcinoma.
Clock mutant promotes osteoarthritis by inhibiting the acetylation of NFκB.
Cell survival controlled by lens-derived Sema3A-Nrp1 is vital on caffeine-suppressed corneal innervation during chick organogenesis.
Ghrelin regulates sepsis‑induced rat acute gastric injury.
Bronchial epithelial cell extracellular vesicles ameliorate epithelial-mesenchymal transition in COPD pathogenesis by alleviating M2 macrophage polarization.
YWHA/14-3-3 proteins recognize phosphorylated TFEB by a noncanonical mode for controlling TFEB cytoplasmic localization.
GDF-15 promotes mitochondrial function and proliferation in neuronal HT22 cells.
circ-CSPP1 promotes proliferation, invasion and migration of ovarian cancer cells by acting as a miR-1236-3p sponge.
Site-Specific Immobilization of β(2)-AR Using O(6)-Benzylguanine Derivative-Functionalized Supporter for High-Throughput Receptor-Targeting Lead Discovery.
Pseudogene RACGAP1P activates RACGAP1/Rho/ERK signalling axis as a competing endogenous RNA to promote hepatocellular carcinoma early recurrence.
iTRAQ-based proteomics analysis reveals the deregulated proteins related to liver toxicity induced by melamine with or without cyanuric acid in mice.
Transection of the cervical sympathetic trunk inhibits the progression of pulmonary arterial hypertension via ERK-1/2 Signalling.
Design and Synthesis of Potent, Selective Inhibitors of Protein Arginine Methyltransferase 4 against Acute Myeloid Leukemia.
The long non-coding RNA H19 induces hypoxia/reoxygenation injury by up-regulating autophagy in the hepatoma carcinoma cells.
Role of PM(2.5) in the development and progression of COPD and its mechanisms.
Epidural adipose tissue-derived mesenchymal stem cell activation induced by lung cancer cells promotes malignancy and EMT of lung cancer.
The up-regulation of two identified wound healing specific proteins-HSP70 and lysozyme in regenerated Eisenia fetida through transcriptome analysis.
Reduction of SIRT1 blunts the protective effects of ischemic post-conditioning in diabetic mice by impairing the Akt signaling pathway.
MiR-664-2 impacts pubertal development in a precocious-puberty rat model through targeting the NMDA receptor-1†.
Protective effects of pyrroloquinoline quinine against oxidative stress-induced cellular senescence and inflammation in human renal tubular epithelial cells via Keap1/Nrf2 signaling pathway.
Metabolism-induced tumor activator 1 (MITA1), an Energy Stress-Inducible Long Noncoding RNA, Promotes Hepatocellular Carcinoma Metastasis.
Exogenous hydrogen sulfide mitigates LPS + ATP-induced inflammation by inhibiting NLRP3 inflammasome activation and promoting autophagy in L02 cells.
Echinacoside Alleviates Hypoxic-Ischemic Brain Injury in Neonatal Rat by Enhancing Antioxidant Capacity and Inhibiting Apoptosis.
Normoxia is not favorable for maintaining stemness of human endothelial progenitor cells.
GSTO1 acts as a mediator in sodium fluoride-induced alterations of learning and memory related factors expressions in the hippocampus cell line.
c‑Jun N‑terminal kinase/transforming growth factor‑β/Smad3 pathway: Is it associated with endoplasmic reticulum stress‑mediated renal interstitial fibrosis?
Toxicity mechanism of sevoflurane in neural stem cells of rats through DNA methylation.
Aloperine suppresses human pulmonary vascular smooth muscle cell proliferation via inhibiting inflammatory response.
TRIM28 protects CARM1 from proteasome-mediated degradation to prevent colorectal cancer metastasis.
Deciphering novel biomarkers of lymph node metastasis of thyroid papillary microcarcinoma using proteomic analysis of ultrasound-guided fine-needle aspiration biopsy samples.
Precise and systematic survey of the efficacy of multicomponent drugs against functional dyspepsia.
Nek2 augments sorafenib resistance by regulating the ubiquitination and localization of β-catenin in hepatocellular carcinoma.
miR-629-5p promotes growth and metastasis of hepatocellular carcinoma by activating β-catenin.
Mitophagy is a protective response against oxidative damage in bone marrow mesenchymal stem cells.
Multi-walled carbon nanotubes promoted lipid accumulation in human aortic smooth muscle cells.
Hypericum perforatum L. supplementation protects sciatic nerve injury-induced apoptotic, inflammatory and oxidative damage to muscle, blood and brain in rats.
S1P promotes inflammation-induced tube formation by HLECs via the S1PR1/NF-κB pathway.
Overexpression of CDCA8 promotes the malignant progression of cutaneous melanoma and leads to poor prognosis.
Regulation of host cell pyroptosis and cytokines production by Mycobacterium tuberculosis effector PPE60 requires LUBAC mediated NF-κB signaling.
Induction of Endoplasmic Reticulum Stress by Cadmium and Its Regulation on Nrf2 Signaling Pathway in Kidneys of Rats.
Radioprotective effects of roxadustat (FG-4592) in haematopoietic system.
BPTF promotes hepatocellular carcinoma growth by modulating hTERT signaling and cancer stem cell traits.
PARP inhibitor re‑sensitizes Adriamycin resistant leukemia cells through DNA damage and apoptosis.
Constitutive androstane receptor weakens the induction of panaxytriol on CYP3A4 by repressing the activation of pregnane X receptor.
DEP domain containing 1 predicts prognosis of hepatocellular carcinoma patients and regulates tumor proliferation and metastasis.
Zerumbone inhibits migration in ESCC via promoting Rac1 ubiquitination.
FS-7 inhibits MGC-803 cells growth in vitro and in vivo via down-regulating glycolysis.
Nerve injury elevates functional Cav3.2 channels in superficial spinal dorsal horn.
DHA-phospholipids (DHA-PL) and EPA-phospholipids (EPA-PL) prevent intestinal dysfunction induced by chronic stress.
Differential response to lead toxicity in rat primary microglia and astrocytes.
Melatonin protects against sepsis-induced cardiac dysfunction by regulating apoptosis and autophagy via activation of SIRT1 in mice.
miR-429 and miR-424-5p inhibit cell proliferation and Ca(2+) influx by downregulating CaSR in pulmonary artery smooth muscle cells.
Sulforaphane Improves Lipid Metabolism by Enhancing Mitochondrial Function and Biogenesis In Vivo and In Vitro.
Citrate reduced oxidative damage in stem cells by regulating cellular redox signaling pathways and represent a potential treatment for oxidative stress-induced diseases.
Strand break-induced replication fork collapse leads to C-circles, C-overhangs and telomeric recombination.
Exogenous Tetranectin Protects Against 1-Methyl-4-Phenylpyridine-Induced Neurotoxicity by Inhibiting Apoptosis and Autophagy Through Ribosomal Protein S6 Kinase Beta-1.
Interferon-alpha promotes immunosuppression through IFNAR1/STAT1 signalling in head and neck squamous cell carcinoma.
A coronary artery disease-associated tRNAThr mutation altered mitochondrial function, apoptosis and angiogenesis.
Protective effect of oxytocin on LPS-induced acute lung injury in mice.
Long noncoding RNA HOTAIR regulates autophagy via the miR-20b-5p/ATG7 axis in hepatic ischemia/reperfusion injury.
Carnosol as a Nrf2 Activator Improves Endothelial Barrier Function Through Antioxidative Mechanisms.
MiR-223-3p functions as a tumor suppressor in lung squamous cell carcinoma by miR-223-3p-mutant p53 regulatory feedback loop.
Autophagy inhibition potentiates the anti-angiogenic property of multikinase inhibitor anlotinib through JAK2/STAT3/VEGFA signaling in non-small cell lung cancer cells.
Protective Effect of Koumine, an Alkaloid from Gelsemium Sempervirens, on Injury Induced by H₂O₂ in IPEC-J2 Cells.
Blockade of glycolysis-dependent contraction by oroxylin a via inhibition of lactate dehydrogenase-a in hepatic stellate cells.
Identification of diterpenoid compounds that interfere with Fli-1 DNA binding to suppress leukemogenesis.
Nano-Gold Loaded with Resveratrol Enhance the Anti-Hepatoma Effect of Resveratrol In Vitro and In Vivo.
Protective effects of a neurokinin 1 receptor antagonist on airway epithelial mitochondria dysfunction in asthmatic mice via Nrf2/HO-1 activation.
Propofol Attenuates Hypoxia/Reoxygenation-Induced Apoptosis and Autophagy in HK-2 Cells by Inhibiting JNK Activation.
Effect of hydrogen-rich water on the Nrf2/ARE signaling pathway in rats with myocardial ischemia-reperfusion injury.
Molecular mechanism of miR-204 regulates proliferation, apoptosis and autophagy of cervical cancer cells by targeting ATF2.
Osteoadherin serves roles in the regulation of apoptosis and growth in MC3T3‑E1 osteoblast cells.
Bexarotene Attenuates Focal Cerebral Ischemia-Reperfusion Injury via the Suppression of JNK/Caspase-3 Signaling Pathway.
Design, synthesis and molecular mechanisms of novel dual inhibitors of heat shock protein 90/phosphoinositide 3-kinase alpha (Hsp90/PI3Kα) against cutaneous melanoma.
Silencing ubiquitin-conjugating enzyme 2C inhibits proliferation and epithelial-mesenchymal transition in pancreatic ductal adenocarcinoma.
Hepatoprotective effects of zinc (II) via cytochrome P-450/reactive oxygen species and canonical apoptosis pathways after arsenite waterborne exposure in common carp.
CircRhoC promotes tumorigenicity and progression in ovarian cancer by functioning as a miR-302e sponge to positively regulate VEGFA.
Protective effects of betaine on diabetic induced disruption of the male mice blood-testis barrier by regulating oxidative stress-mediated p38 MAPK pathways.
Glycogen phosphorylase B promotes ovarian cancer progression via Wnt/β-catenin signaling and is regulated by miR-133a-3p.
Differential immune responses of C57BL/6 mice to infection by Salmonella enterica serovar Typhimurium strain SL1344, CVCC541 and CMCC50115.
circPUM1 Promotes Tumorigenesis and Progression of Ovarian Cancer by Sponging miR-615-5p and miR-6753-5p.
Dietary Curcumin Supplementation Increases Antioxidant Capacity, Upregulates Nrf2 and Hmox1 Levels in the Liver of Piglet Model with Intrauterine Growth Retardation.
ATXN3 promotes breast cancer metastasis by deubiquitinating KLF4.
Autophagy Attenuation Hampers Progesterone Synthesis during the Development of Pregnant Corpus Luteum.
Dietary Dihydroartemisinin Supplementation Attenuates Hepatic Oxidative Damage of Weaned Piglets with Intrauterine Growth Retardation through the Nrf2/ARE Signaling Pathway.
LPS Inhibits Fatty Acid Absorption in Enterocytes through TNF-α Secreted by Macrophages.
Icariin targets Nrf2 signaling to inhibit microglia-mediated neuroinflammation.
Disubstituted Dithiolethione ACDT Exerts Neuroprotective Effects Against 6-Hydroxydopamine-Induced Oxidative Stress in SH-SY5Y Cells.
Abnormal serum vitamin A levels and retinoic acid receptor α expression patterns in children with anorectal malformation.
Hypoxic postconditioning activates the Wnt/β-catenin pathway and protects against transient global cerebral ischemia through Dkk1 Inhibition and GSK-3β inactivation.
Exosomes from high glucose-treated macrophages activate glomerular mesangial cells via TGF-β1/Smad3 pathway in vivo and in vitro.
Bone marrow mesenchymal stem cells could reduce the toxic effects of hexavalent chromium on the liver by decreasing endoplasmic reticulum stress-mediated apoptosis via SIRT1/HIF-1α signaling pathway in rats.
Knockdown of LncRNA SCAMP1 suppressed malignant biological behaviours of glioma cells via modulating miR-499a-5p/LMX1A/NLRC5 pathway.
RING finger protein 10 is a potential drug target for diabetic vascular complications.
Phenotypic transition of tumor cells between epithelial- and mesenchymal-like state during adaptation to acidosis.
Bilirubin alleviates alum-induced peritonitis through inactivation of NLRP3 inflammasome.
The expression of cerebrospinal fluid exosomal miR-630 plays an important role in the dysfunction of endothelial cells after subarachnoid hemorrhage.
Cordycepin alleviates hepatic lipid accumulation by inducing protective autophagy via PKA/mTOR pathway.
Brilliant Blue G Inhibits Inflammasome Activation and Reduces Disruption of Blood-Spinal Cord Barrier Induced by Spinal Cord Injury in Rats.
miR-205-5p regulates epithelial-mesenchymal transition by targeting PTEN via PI3K/AKT signaling pathway in cisplatin-resistant nasopharyngeal carcinoma cells.
Rho-kinase inhibitor attenuates airway mucus hypersecretion and inflammation partly by downregulation of IL-13 and the JNK1/2-AP1 signaling pathway.
Selective ERK1/2 agonists isolated from Melia azedarach with potent anti-leukemic activity.
MiR-146b accelerates osteoarthritis progression by targeting alpha-2-macroglobulin.
Identification of proteomic signatures associated with COPD frequent exacerbators.
Changes among TGF-β1(+) Breg cells and helper T cell subsets in a murine model of allergic rhinitis with prolonged OVA challenge.
CD36 plays a negative role in the regulation of lipophagy in hepatocytes through an AMPK-dependent pathway.
Netrin‑1 interference potentiates epithelial‑to‑mesenchymal transition through the PI3K/AKT pathway under the hypoxic microenvironment conditions of non‑small cell lung cancer.
Simvastatin ameliorates total liver ischemia/reperfusion injury via KLF2-mediated mechanism in rats.
High-mobility group box 1 protein modulated proliferation and radioresistance in esophageal squamous cell carcinoma.
Nicotinate-curcumin ameliorates cognitive impairment in diabetic rats by rescuing autophagic flux in CA1 hippocampus.
CCL18 promotes the metastasis of squamous cell carcinoma of the head and neck through MTDH-NF-κB signalling pathway.
SIRT5-mediated SDHA desuccinylation promotes clear cell renal cell carcinoma tumorigenesis.
Changes in the levels of 12/15-lipoxygenase, apoptosis-related proteins and inflammatory factors in the cortex of diabetic rats and the neuroprotection of baicalein.
The toxicity of multi-walled carbon nanotubes (MWCNTs) to human endothelial cells: The influence of diameters of MWCNTs.
Effects of myostatin deficiency on PGC-1α and FNDC5 expression in three different murine muscle types.
Prolonged high-glucose exposure decreased SREBP-1/FASN/ACC in Schwann cells of diabetic mice via blocking PI3K/Akt pathway.
MiRNA-29a modulates visceral hyperalgesia in irritable bowel syndrome by targeting HTR7.
Long non-coding RNA GBCDRlnc1 induces chemoresistance of gallbladder cancer cells by activating autophagy.
The Anticonvulsant Effects of Baldrinal on Pilocarpine-Induced convulsion in Adult Male Mice.
Effects of agomelatine in rotenone-induced Parkinson's disease in rats.
Ginsenoside Rk1 induces cell cycle arrest and apoptosis in MDA-MB-231 triple negative breast cancer cells.
The effect of di-2-ethylhexyl phthalate on inflammation and lipid metabolic disorder in rats.
Transketolase (TKT) activity and nuclear localization promote hepatocellular carcinoma in a metabolic and a non-metabolic manner.
Microglial NLRP3 inflammasome activation mediates IL-1β release and contributes to central sensitization in a recurrent nitroglycerin-induced migraine model.
TCF7L1 indicates prognosis and promotes proliferation through activation of Keap1/NRF2 in gastric cancer.
Inhibition of soluble epoxide hydrolase ameliorates hyperhomocysteinemia-induced hepatic steatosis by enhancing β-oxidation of fatty acid in mice.
The PERK-EIF2α-ATF4 signaling branch regulates osteoblast differentiation and proliferation by PTH.
High Expression of lncRNA AFAP1-AS1 Promotes the Progression of Colon Cancer and Predicts Poor Prognosis.
Trio-Based Deep Sequencing Reveals a Low Incidence of Off-Target Mutations in the Offspring of Genetically Edited Goats.
Fangchinoline Ameliorates the Expressions of Angiogenic Molecule in Cerebral Ischemia Induced Neuronal Degeneration in Neonatal Rats.
Snx27 Deletion Promotes Recovery From Spinal Cord Injury by Neuroprotection and Reduces Macrophage/Microglia Proliferation.
Adipocytes fuel gastric cancer omental metastasis via PITPNC1-mediated fatty acid metabolic reprogramming.
Th17 cell-derived IL-17A promoted tumor progression via STAT3/NF-κB/Notch1 signaling in non-small cell lung cancer.
Long Noncoding RNA HOTTIP Promotes Mouse Hepatic Stellate Cell Activation via Downregulating miR-148a.
The FOXK1-CCDC43 Axis Promotes the Invasion and Metastasis of Colorectal Cancer Cells.
Tumor-Secreted Exosomal miR-222 Promotes Tumor Progression via Regulating P27 Expression and Re-Localization in Pancreatic Cancer.
High Concentration of Aspirin Induces Apoptosis in Rat Tendon Stem Cells via Inhibition of the Wnt/β-Catenin Pathway.
Mesenchymal Stem Cell-Derived Exosomes Reduce A1 Astrocytes via Downregulation of Phosphorylated NFκB P65 Subunit in Spinal Cord Injury.
LncRNA PCGEM1 Induces Ovarian Carcinoma Tumorigenesis and Progression Through RhoA Pathway.
The influence of GAPT extraction on synapse loss of APPswe/PS1dE9 transgenic mice via adjusting Bcl-2/Bax balance.
The Potential Protective Effect of Curcumin on Amyloid-β-42 Induced Cytotoxicity in HT-22 Cells.
Ingredients from Litsea garrettii as Potential Preventive Agents against Oxidative Insult and Inflammatory Response.
Serum and Ectopic Endometrium from Women with Endometriosis Modulate Macrophage M1/M2 Polarization via the Smad2/Smad3 Pathway.
Dysfunction of Nrf2-ARE Signaling Pathway: Potential Pathogenesis in the Development of Neurocognitive Impairment in Patients with Moderate to Severe Obstructive Sleep Apnea-Hypopnea Syndrome.
Fucosterol Protects against Concanavalin A-Induced Acute Liver Injury: Focus on P38 MAPK/NF-κB Pathway Activity.
Effects of Chicory on Serum Uric Acid, Renal Function, and GLUT9 Expression in Hyperuricaemic Rats with Renal Injury and In Vitro Verification with Cells.
Necrostatin-1 promotes ectopic periodontal tissue like structure regeneration in LPS-treated PDLSCs.
Targeting MAPK Pathways by Naringenin Modulates Microglia M1/M2 Polarization in Lipopolysaccharide-Stimulated Cultures.
Arsenic sulfide amplifies JQ1 toxicity via mitochondrial pathway in gastric and colon cancer cells.
Over-expression of prolyl isomerase Pin1 promotes cervical tumorigenesis and metastasis.
Natural antisense transcript of hypoxia-inducible factor 1 regulates hypoxic cell apoptosis in epithelial ovarian cancer.
Contribution of dysregulated circRNA_100876 to proliferation and metastasis of esophageal squamous cell carcinoma.
Combination Treatment of Icariin and L-DOPA Against 6-OHDA-Lesioned Dopamine Neurotoxicity.
Lithium chloride inhibits cell survival, overcomes drug resistance, and triggers apoptosis in multiple myeloma via activation of the Wnt/β-catenin pathway.
Leucine Carboxyl Methyltransferase Downregulation and Protein Phosphatase Methylesterase Upregulation Contribute Toward the Inhibition of Protein Phosphatase 2A by α-Synuclein.
Cdk5 Inhibitory Peptide Prevents Loss of Dopaminergic Neurons and Alleviates Behavioral Changes in an MPTP Induced Parkinson's Disease Mouse Model.
lncRNA DLEU1 contributes to tumorigenesis and development of endometrial carcinoma by targeting mTOR.
Curcumin attenuates resistance to irinotecan via induction of apoptosis of cancer stem cells in chemoresistant colon cancer cells.
MiR-20a-3p regulates TGF-β1/Survivin pathway to affect keratinocytes proliferation and apoptosis by targeting SFMBT1 in vitro.
Resveratrol relieves particulate matter (mean diameter < 2.5 μm)-induced oxidative injury of lung cells through attenuation of autophagy deregulation.
Artemisitene suppresses tumorigenesis by inducing DNA damage through deregulating c-Myc-topoisomerase pathway.
Knockdown of long noncoding RNA GHET1 inhibits cell‑cycle progression and invasion of gastric cancer cells.
TAM Infiltration Differences in "Tumor-First" and " ZHENG-First" Models and the Underlying Inflammatory Molecular Mechanism in Pancreatic Cancer.
Overexpression of SMARCA2 or CAMK2D is associated with cisplatin resistance in human epithelial ovarian cancer.
Effects of SB202190 on expression levels of IL-6 and NF-κB in flap ischemia-reperfusion injury.
2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone, a potent Nrf2/ARE pathway inhibitor, reverses drug resistance by decreasing glutathione synthesis and drug efflux in BEL-7402/5-FU cells.
Bexarotene protects against neurotoxicity partially through a PPARγ-dependent mechanism in mice following traumatic brain injury.
miR-383 negatively regulates osteoblastic differentiation of bone marrow mesenchymal stem cells in rats by targeting Satb2.
Oxymatrine Inhibits Transforming Growth Factor β1 (TGF-β1)-Induced Cardiac Fibroblast-to-Myofibroblast Transformation (FMT) by Mediating the Notch Signaling Pathway In Vitro.
Lactate enhanced the effect of parathyroid hormone on osteoblast differentiation via GPR81-PKC-Akt signaling.
H2A.Z.1 crosstalk with H3K56-acetylation controls gliogenesis through the transcription of folate receptor.
RING finger protein 10 prevents neointimal hyperplasia by promoting apoptosis in vitro and in vivo.
miR‑92b promotes autophagy and suppresses viability and invasion in breast cancer by targeting EZH2.
Acrolein-induced autophagy-dependent apoptosis via activation of the lysosomal-mitochondrial pathway in EAhy926 cells.
Erythropoietin Treatment Ameliorates Lupus Nephritis of MRL/lpr Mice.
lncRNA GAS5 inhibits colorectal cancer cell proliferation via the miR‑182‑5p/FOXO3a axis.
MicroRNA‑106a regulates the proliferation and invasion of human osteosarcoma cells by targeting VNN2.
Association between Tim‑3 and Gal‑9 expression and gastric cancer prognosis.
Low-Dose Radiation Enhanced Inhibition of Breast Tumor Xenograft and Reduced Myocardial Injury Induced by Doxorubicin.
High expression of WNT7A predicts poor prognosis and promote tumor metastasis in pancreatic ductal adenocarcinoma.
Construction of a High-Efficiency Drug and Gene Co-Delivery System for Cancer Therapy from a pH-Sensitive Supramolecular Inclusion between Oligoethylenimine- graft-β-cyclodextrin and Hyperbranched Polyglycerol Derivative.
ERα is a negative regulator of PD-L1 gene transcription in breast cancer.
Temozolomide-Perillyl alcohol conjugate impairs Mitophagy flux by inducing lysosomal dysfunction in non-small cell lung Cancer cells and sensitizes them to irradiation.
CNTNAP4 Impacts Epilepsy Through GABAA Receptors Regulation: Evidence From Temporal Lobe Epilepsy Patients and Mouse Models.
Cold-induced protein RBM3 orchestrates neurogenesis via modulating Yap mRNA stability in cold stress.
BF211, a derivative of bufalin, enhances the cytocidal effects in multiple myeloma cells by inhibiting the IL-6/JAK2/STAT3 pathway.
Biological functions and clinical significance of the newly identified long non‑coding RNA RP1‑85F18.6 in colorectal cancer.
FGF9 modulates Schwann cell myelination in developing nerves and induces a pro-inflammatory environment during injury.
Pyroptosis of HUVECs can be induced by heat stroke.
An E-selectin targeting and MMP-2-responsive dextran-curcumin polymeric prodrug for targeted therapy of acute kidney injury.
Polybrominated Diphenyl Ethers Quinone Induced Parthanatos-like Cell Death through a Reactive Oxygen Species-Associated Poly(ADP-ribose) Polymerase 1 Signaling.
Luteolin sensitizes the antitumor effect of cisplatin in drug-resistant ovarian cancer via induction of apoptosis and inhibition of cell migration and invasion.
Retraction: Cd induces G2/M cell cycle arrest by up-regulating miR-133b via directly targeting PPP2R2D in L02 hepatocytes.
Lysyl oxidase blockade ameliorates anovulation in polycystic ovary syndrome.
Decrease of galectin-3 in keratinocytes: A potential diagnostic marker and a critical contributor to the pathogenesis of psoriasis.
The inhibitory effect in Fraxinellone on oxidative stress-induced senescence correlates with AMP-activated protein kinase-dependent autophagy restoration.
PD-L1 confers glioblastoma multiforme malignancy via Ras binding and Ras/Erk/EMT activation.
Reversing Multidrug Resistance by Multiplexed Gene Silencing for Enhanced Breast Cancer Chemotherapy.
Interfering RNA against PKC-α inhibits TNF-α-induced IP(3)R1 expression and improves glomerular filtration rate in rats with fulminant hepatic failure.
Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.
Donor Treatment With a Hypoxia-Inducible Factor-1 Agonist Prevents Donation After Cardiac Death Liver Graft Injury in a Rat Isolated Perfusion Model.
Proteomics analysis of altered proteins in kidney of mice with aristolochic acid nephropathy using the fluorogenic derivatization-liquid chromatography-tandem mass spectrometry method.
Expression of diaphragmatic myostatin and correlation with apoptosis in rats with chronic obstructive pulmonary disease.
Lipoxin A4 improves erectile dysfunction in rats with type I diabetes by inhibiting oxidative stress and corporal fibrosis.
Marine Bacterial Polysaccharide EPS11 Inhibits Cancer Cell Growth via Blocking Cell Adhesion and Stimulating Anoikis.
AMPK alleviates endoplasmic reticulum stress by inducing the ER-chaperone ORP150 via FOXO1 to protect human bronchial cells from apoptosis.
7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway.
In vitro inhibition of porcine reproductive and respiratory syndrome virus replication by short antisense oligonucleotides with locked nucleic acid modification.
Epidermal Growth Factor, through Alleviating Oxidative Stress, Protect IPEC-J2 Cells from Lipopolysaccharides-Induced Apoptosis.
Early Postnatal Exposure to Airborne Fine Particulate Matter Induces Autism-like Phenotypes in Male Rats.
All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway.
Formononetin inhibits colon carcinoma cell growth and invasion by microRNA‑149‑mediated EphB3 downregulation and inhibition of PI3K/AKT and STAT3 signaling pathways.
Expression of tumor suppressor programmed cell death 4 in endometrioid endometrial carcinomas and clinicopathological significance.
FPOA induces apoptosis in HeLa human cervical cancer cells through a caspase-mediated pathway.
Pseudo-Ginsenoside Rh2 induces A549 cells apoptosis via the Ras/Raf/ERK/p53 pathway.
Effects of Tumor Necrosis Factor α (TNF-α) and Interleukina 10 (IL-10) on Intercellular Cell Adhesion Molecule-1 (ICAM-1) and Cluster of Differentiation 31 (CD31) in Human Coronary Artery Endothelial Cells.
Chronic cold exposure results in subcutaneous adipose tissue browning and altered global metabolism in Qinghai-Tibetan plateau pika (Ochotona curzoniae).
Regional up-regulation of NOX2 contributes to the differential vulnerability of outer hair cells to neomycin.
Atrazine exposure improves the proliferation of H22 cells in vitro and in vivo.
Down-regulation of IFIT3 protects liver from ischemia-reperfusion injury.
Long non-coding RNA (lncRNA) MAGI2-AS3 inhibits breast cancer cell growth by targeting the Fas/FasL signalling pathway.
Wnt/β-catenin modulates chronic tobacco smoke exposure-induced acquisition of pulmonary cancer stem cell properties and diallyl trisulfide intervention.
A Polysaccharide Isolated from Dictyophora indusiata Promotes Recovery from Antibiotic-Driven Intestinal Dysbiosis and Improves Gut Epithelial Barrier Function in a Mouse Model.
Glutathione Reduction of Patulin-Evoked Cytotoxicity in HEK293 Cells by the Prevention of Oxidative Damage and the Mitochondrial Apoptotic Pathway.
Intermittent streptozotocin administration induces behavioral and pathological features relevant to Alzheimer's disease and vascular dementia.
Baicalein inhibits cervical cancer progression via downregulating long noncoding RNA BDLNR and its downstream PI3K/Akt pathway.
Activation of Nrf2 pathway and inhibition of NLRP3 inflammasome activation contribute to the protective effect of chlorogenic acid on acute liver injury.
Nitric oxide, afferent sensory nerves, and antioxidative enzymes in the mechanism of protection mediated by tricarbonyldichlororuthenium(II) dimer and sodium hydrosulfide against aspirin-induced gastric damage.
Inhibition of Rho kinase protects against colitis in mice by attenuating intestinal epithelial barrier dysfunction via MLC and the NF-κB pathway.
Anticancer effect of SZC015 on pancreatic cancer via mitochondria-dependent apoptosis and the constitutive suppression of activated nuclear factor κB and STAT3 in vitro and in vivo.
Thrombopoietin protects H9C2 cells from excessive autophagy and apoptosis in doxorubicin-induced cardiotoxicity.
Exogenous oxidants activate nuclear factor kappa B through Toll-like receptor 4 stimulation to maintain inflammatory phenotype in macrophage.
Experimental evidence of good efficacy and reduced toxicity with peptide-doxorubicin to treat gastric cancer.
The protective role of low-concentration alcohol in high-fructose induced adverse cardiovascular events in mice.
Nicotine Induces Progressive Properties of Lung Adenocarcinoma A549 Cells by Inhibiting Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Expression and Plasma Membrane Localization.
Effects of calycosin against high-fat diet-induced nonalcoholic fatty liver disease in mice.
Genipin alleviates high-fat diet-induced hyperlipidemia and hepatic lipid accumulation in mice via miR-142a-5p/SREBP-1c axis.
Di-(2-ethylhexyl)-phthalate induces glucose metabolic disorder in adolescent rats.
RNF20 controls astrocytic differentiation through epigenetic regulation of STAT3 in the developing brain.
Construction and protective immunogenicity of DNA vaccine pNMB0315 against Neisseria meningitidis serogroup B.
The N-terminal ubiquitin-associated domain of Cezanne is crucial for its function to suppress NF-κB pathway.
miR-429 suppresses tumor migration and invasion by targeting CRKL in hepatocellular carcinoma via inhibiting Raf/MEK/ERK pathway and epithelial-mesenchymal transition.
Synergistic neuroprotective effect of rasagiline and idebenone against retinal ischemia-reperfusion injury via the Lin28-let-7-Dicer pathway.
Collagen-based three-dimensional culture microenvironment promotes epithelial to mesenchymal transition and drug resistance of human ovarian cancer in vitro.
[Impact of Cystic Fibrosis Transmembrane Conductance Regulator on Malignant Properties of KRAS Mutant Lung Adenocarcinoma A549 Cells].
RACK1 is indispensable for porcine reproductive and respiratory syndrome virus replication and NF-κB activation in Marc-145 cells.
Neuroprotective Effect of Anethole Against Neuropathic Pain Induced by Chronic Constriction Injury of the Sciatic Nerve in Mice.
Relationship of Epidermal Growth Factor Receptor Expression with Clinical Symptoms and Metastasis of Invasive Breast Cancer.
Role of Long Noncoding RNA 799 in the Metastasis of Cervical Cancer through Upregulation of TBL1XR1 Expression.
WISP1 mediates lung injury following hepatic ischemia reperfusion dependent on TLR4 in mice.
The Traditional Chinese Medicine MLC901 inhibits inflammation processes after focal cerebral ischemia.
Cancer-derived exosomal miR-25-3p promotes pre-metastatic niche formation by inducing vascular permeability and angiogenesis.
Crotonols A and B, two rare tigliane diterpenoid derivatives against K562 cells from Croton tiglium.
Metformin suppresses growth and adrenocorticotrophic hormone secretion in mouse pituitary corticotroph tumor AtT20 cells.
Lactobacillus helveticus KLDS1.8701 alleviates d-galactose-induced aging by regulating Nrf-2 and gut microbiota in mice.
Whole-exome sequencing revealed HKDC1 as a candidate gene associated with autosomal-recessive retinitis pigmentosa.
Transcription Factor FOXO3a Is a Negative Regulator of Cytotoxicity of Fusarium mycotoxin in GES-1 Cells.
Protective effects of ginsenoside Rg1 against lipopolysaccharide/d-galactosamine-induced acute liver injury in mice through inhibiting toll-like receptor 4 signaling pathway.
Dietary eicosapentaenoic acid normalizes hippocampal omega-3 and 6 polyunsaturated fatty acid profile, attenuates glial activation and regulates BDNF function in a rodent model of neuroinflammation induced by central interleukin-1β administration.
TRPC1/3/6 inhibition attenuates the TGF-β1-induced epithelial-mesenchymal transition in gastric cancer via the Ras/Raf1/ERK signaling pathway.
Knockdown of TIPE2 increases the proliferation in lipopolysaccharide-stimulated gastric cancer cells.
Phosphoglycerate Mutase 1 (PGAM1) Promotes Pancreatic Ductal Adenocarcinoma (PDAC) Metastasis by Acting as a Novel Downstream Target of the PI3K/Akt/mTOR Pathway.
Anti-inflammatory activities and potential mechanisms of phenolic acids isolated from Salvia miltiorrhiza f. alba roots in THP-1 macrophages.
Hepatic, Metabolic, and Toxicity Evaluation of Repeated Oral Administration of SnS2 Nanoflowers in Mice.
Uncoupling protein 1 expression in adipocytes derived from skeletal muscle fibro/adipogenic progenitors is under genetic and hormonal control.
Aspm knockout ferret reveals an evolutionary mechanism governing cerebral cortical size.
CHOP induces apoptosis by affecting brain iron metabolism in rats with subarachnoid hemorrhage.
LPS‑induced proinflammatory cytokine expression in human airway epithelial cells and macrophages via NF‑κB, STAT3 or AP‑1 activation.
Regulation on SIRT1-PGC-1α/Nrf2 pathway together with selective inhibition of aldose reductase makes compound hr5F a potential agent for the treatment of diabetic complications.
Cationic nanomicelles derived from Pluronic F127 as delivery vehicles of Chinese herbal medicine active components of ursolic acid for colorectal cancer treatment.
DL-3-n-butylphthalide alleviates vascular cognitive impairment induced by chronic cerebral hypoperfusion by activating the Akt/Nrf2 signaling pathway in the hippocampus of rats.
Novel decellularized liver matrix-alginate hybrid gel beads for the 3D culture of hepatocellular carcinoma cells.
Volatile Oil from Amomi Fructus Attenuates 5-Fluorouracil-Induced Intestinal Mucositis.
Inhibition of the TRPM2 and TRPV1 Channels through Hypericum perforatum in Sciatic Nerve Injury-induced Rats Demonstrates their Key Role in Apoptosis and Mitochondrial Oxidative Stress of Sciatic Nerve and Dorsal Root Ganglion.
Whole exome-wide association study identifies a missense variant in SLC2A4RG associated with glioblastoma risk.
Inhibition of HIF-1α by PX-478 suppresses tumor growth of esophageal squamous cell cancer in vitro and in vivo.
Rosiglitazone Inhibits Angiotensin II-Induced Proliferation of Glomerular Mesangial Cells via the Gαq/Plcβ4/TRPC Signaling Pathway.
Ox-LDL-Induced MicroRNA-155 Promotes Autophagy in Human Endothelial Cells via Repressing the Rheb/ mTOR Pathway.
Chondroprotective Effects and Multitarget Mechanisms of Fu Yuan Capsule in a Rat Osteoarthritis Model.
Electroacupuncture Improved Hippocampal Neurogenesis following Traumatic Brain Injury in Mice through Inhibition of TLR4 Signaling Pathway.
Pretreatment Donors after Circulatory Death with Simvastatin Alleviates Liver Ischemia Reperfusion Injury through a KLF2-Dependent Mechanism in Rat.
Differential inhibition of activity, activation and gene expression of MMP-9 in THP-1 cells by azithromycin and minocycline versus bortezomib: A comparative study.
Hyperlipidemia impairs erectile function in rats by causing cavernosal fibrosis.
Mechanism of Lycium barbarum polysaccharides on primary cultured rat hippocampal neurons.
Histone variant H3.3 orchestrates neural stem cell differentiation in the developing brain.
Hydrogen sulfide prevents homocysteine‑induced endoplasmic reticulum stress in PC12 cells by upregulating SIRT‑1.
Exosomes derived from bone marrow stromal cells decrease the sensitivity of leukemic cells to etoposide.
Roux-en-Y gastric bypass surgery suppresses hypothalamic PTP1B protein level and alleviates leptin resistance in obese rats.
Low Frequency Magnetic Fields Induce Autophagy-associated Cell Death in Lung Cancer through miR-486-mediated Inhibition of Akt/mTOR Signaling Pathway.
AMPK activation-dependent autophagy compromises oleanolic acid-induced cytotoxicity in human bladder cancer cells.
Downregulation of BZW2 inhibits osteosarcoma cell growth by inactivating the Akt/mTOR signaling pathway.
Role of autophagy in cadmium-induced testicular injury.
Effects of hydrogen sulfide on inducible nitric oxide synthase activity and expression of cardiomyocytes in diabetic rats.
Antiplatelet drug ticagrelor delays gastric ulcer healing in rats.
HOTAIR regulates HK2 expression by binding endogenous miR-125 and miR-143 in oesophageal squamous cell carcinoma progression.
Functional characterization of a novel transcript of ERCC1 in chemotherapy resistance of ovarian cancer.
A novel protein derived from lamprey supraneural body tissue with efficient cytocidal actions against tumor cells.
LINC00461, a long non-coding RNA, is important for the proliferation and migration of glioma cells.
A high-fat, high-protein diet attenuates the negative impact of casein-induced chronic inflammation on testicular steroidogenesis and sperm parameters in adult mice.
Neuroprotective effect of liquiritin against neuropathic pain induced by chronic constriction injury of the sciatic nerve in mice.
Hepatoprotective effect of quercetin against LPS/d-GalN induced acute liver injury in mice by inhibiting the IKK/NF-κB and MAPK signal pathways.
Neuroprotective Effect of Chitosan Oligosaccharide on Hypoxic-Ischemic Brain Damage in Neonatal Rats.
CMIP is oncogenic in human gastric cancer cells.
Dlitiazem inhibits the oxidative stress induced by angiotensin II through growth hormone secretagogue receptor type 1a in human umbilicus vein endothelial cells.
Protective effects of aloperine on monocrotaline-induced pulmonary hypertension in rats.
ApoA-I/SR-BI modulates S1P/S1PR2-mediated inflammation through the PI3K/Akt signaling pathway in HUVECs.
Up-regulated BAFF and BAFF receptor expression in patients with intractable temporal lobe epilepsy and a pilocarpine-induced epilepsy rat model.
β-Caryophyllene Pretreatment Alleviates Focal Cerebral Ischemia-Reperfusion Injury by Activating PI3K/Akt Signaling Pathway.
AGR2 ameliorates tumor necrosis factor-α-induced epithelial barrier dysfunction via suppression of NF-κB p65-mediated MLCK/p-MLC pathway activation.
Relationship between abnormal TOX3 gene methylation and polycystic ovarian syndrome.
Icariin inhibits MMP‑1, MMP‑3 and MMP‑13 expression through MAPK pathways in IL‑1β‑stimulated SW1353 chondrosarcoma cells.
A novel role of fragile X mental retardation protein in pre-mRNA alternative splicing through RNA-binding protein 14.
PLAA Mutations Cause a Lethal Infantile Epileptic Encephalopathy by Disrupting Ubiquitin-Mediated Endolysosomal Degradation of Synaptic Proteins.
The Long Noncoding RNA NEAT1 Exerts Antihantaviral Effects by Acting as Positive Feedback for RIG-I Signaling.
The Anticonvulsant and Neuroprotective Effects of Oxysophocarpine on Pilocarpine-Induced Convulsions in Adult Male Mice.
KIAA1199 is induced by inflammation and enhances malignant phenotype in pancreatic cancer.
Generation and characteristics of human Sertoli cell line immortalized by overexpression of human telomerase.
Beneficial effects of Lycium barbarum polysaccharide on spermatogenesis by improving antioxidant activity and inhibiting apoptosis in streptozotocin-induced diabetic male mice.
Mitochondrial dynamics changes with age in an APPsw/PS1dE9 mouse model of Alzheimer's disease.
HMGB1-induced autophagy: a new pathway to maintain Treg function during chronic hepatitis B virus infection.
TGF-β1 promotes human hepatic carcinoma HepG2 cells invasion by upregulating autophagy.
DDX50 inhibits the replication of dengue virus 2 by upregulating IFN-β production.
Generation and characterization of induced pluripotent stem cells from guinea pig fetal fibroblasts.
Esculetin induces apoptosis of SMMC-7721 cells through IGF-1/PI3K/Akt-mediated mitochondrial pathways.
Estrogen receptor-α36 is involved in icaritin induced growth inhibition of triple-negative breast cancer cells.
Nrf2-Knockout Protects from Intestinal Injuries in C57BL/6J Mice Following Abdominal Irradiation with γ Rays.
Hypoxia-inducible factor-1 alpha is involved in RIP-induced necroptosis caused by in vitro and in vivo ischemic brain injury.
SHIP, a novel factor to ameliorate extracellular matrix accumulation via suppressing PI3K/Akt/CTGF signaling in diabetic kidney disease.
Effect of Oleracein E, a Neuroprotective Tetrahydroisoquinoline, on Rotenone-Induced Parkinson's Disease Cell and Animal Models.
BMP4 promotes mouse iPS cell differentiation to male germ cells via Smad1/5, Gata4, Id1 and Id2.
Induction of apoptosis by FFJ-5, a novel naphthoquinone compound, occurs via downregulation of PKM2 in A549 and HepG2 cells.
Coptisine from Rhizoma Coptidis Suppresses HCT-116 Cells-related Tumor Growth in vitro and in vivo.
TRIM14 regulates cell proliferation and invasion in osteosarcoma via promotion of the AKT signaling pathway.
Antitumor effects of baicalin on ovarian cancer cells through induction of cell apoptosis and inhibition of cell migration in vitro.
Chloroform extract of Hedyotis diffusa Willd inhibits viability of human colorectal cancer cells via suppression of AKT and ERK signaling pathways.
Inhibition of chemotherapy-induced apoptosis of testicular cells by squid ink polysaccharide.
Involvement of TRPM2 and TRPV1 channels on hyperalgesia, apoptosis and oxidative stress in rat fibromyalgia model: Protective role of selenium.
Inhibition of Calcineurin A by FK506 Suppresses Seizures and Reduces the Expression of GluN2B in Membrane Fraction.
miR-367 promotes tumor growth by inhibiting FBXW7 in NSCLC.
IGFBP-rP1 acts as a potential tumor suppressor via the suppression of ERK signaling pathway in endometrial cancer cells.
Src Homology 2 Domain-Containing Inositol 5'-Phosphatase Ameliorates High Glucose-Induced Extracellular Matrix Deposition via the Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway in Renal Tubular Epithelial Cells.
miR-133b Inhibits Cell Growth, Migration, and Invasion by Targeting MMP9 in Non-Small Cell Lung Cancer.
Melatonin ameliorates restraint stress-induced oxidative stress and apoptosis in testicular cells via NF-κB/iNOS and Nrf2/ HO-1 signaling pathway.
Epigallocatechin-3-gallate inhibits H(2)O(2)-induced apoptosis in Mouse Vascular Smooth Muscle Cells via 67kD Laminin Receptor.
Phosphocreatine protects endothelial cells from Methylglyoxal induced oxidative stress and apoptosis via the regulation of PI3K/Akt/eNOS and NF-κB pathway.
Long non-coding RNA TUG1 promotes cell proliferation and metastasis by negatively regulating miR-300 in gallbladder carcinoma.
The Circadian Gene Clock Regulates Bone Formation Via PDIA3.
Terrein performs antitumor functions on esophageal cancer cells by inhibiting cell proliferation and synergistic interaction with cisplatin.
miR-150 is downregulated in osteosarcoma and suppresses cell proliferation, migration and invasion by targeting ROCK1.
Boschniakia Rossica Polysaccharide Triggers Laryngeal Carcinoma Cell Apoptosis by Regulating Expression of Bcl-2, Caspase-3, and P53.
Tumor-associated macrophages promote Ezrin phosphorylation-mediated epithelial-mesenchymal transition in lung adenocarcinoma through FUT4/LeY up-regulation.
The acute exposure of tetrachloro-p-benzoquinone (a.k.a. chloranil) triggers inflammation and neurological dysfunction via Toll-like receptor 4 signaling: The protective role of melatonin preconditioning.
Enhanced tenogenic differentiation and tendon-like tissue formation by CHIP overexpression in tendon-derived stem cells.
1,2-Dichloroethane impairs glucose and lipid homeostasis in the livers of NIH Swiss mice.
High-dose irradiation in combination with toll-like receptor 9 agonist CpG oligodeoxynucleotide 7909 downregulates PD-L1 expression via the NF-κB signaling pathway in non-small cell lung cancer cells.
Radiation promotes epithelial-to-mesenchymal transition and invasion of pancreatic cancer cell by activating carcinoma-associated fibroblasts.
Targeting Dynamin 2 as a Novel Pathway to Inhibit Cardiomyocyte Apoptosis Following Oxidative Stress.
N-Methyl-D-aspartate Receptor Excessive Activation Inhibited Fetal Rat Lung Development In Vivo and In Vitro.
The Generation and Characterization of Recombinant Protein and Antibodies of Clostridium perfringens Beta2 Toxin.
Quantitative Proteomic Profiling the Molecular Signatures of Annexin A5 in Lung Squamous Carcinoma Cells.
The long noncoding RNA MALAT1 regulates the lipopolysaccharide-induced inflammatory response through its interaction with NF-κB.
Lactobacillus rhamnosus induced epithelial cell apoptosis, ameliorates inflammation and prevents colon cancer development in an animal model.
From the Cover: Tetrachlorobenzoquinone Exerts Neurological Proinflammatory Activity by Promoting HMGB1 Release, Which Induces TLR4 Clustering within the Lipid Raft.
Hydrogen Sulfide and Carbon Monoxide Protect Gastric Mucosa Compromised by Mild Stress Against Alendronate Injury.
Quantitative proteomics reveals molecular mechanism of gamabufotalin and its potential inhibition on Hsp90 in lung cancer.
Progranulin deficiency leads to severe inflammation, lung injury and cell death in a mouse model of endotoxic shock.
The tumor suppressor PTEN has a critical role in antiviral innate immunity.
AMPK-mediated up-regulation of mTORC2 and MCL-1 compromises the anti-cancer effects of aspirin.
Potassium supplementation inhibits IL-17A production induced by salt loading in human T lymphocytes via p38/MAPK-SGK1 pathway.
Myricetin ameliorates brain injury and neurological deficits via Nrf2 activation after experimental stroke in middle-aged rats.
Carboxy-terminal modulator protein attenuated extracellular matrix deposit by inhibiting phospho-Akt, TGF-β1 and α-SMA in kidneys of diabetic mice.
Lipodystrophy and severe metabolic dysfunction in mice with adipose tissue-specific insulin receptor ablation.
miR-223 enhances the sensitivity of non-small cell lung cancer cells to erlotinib by targeting the insulin-like growth factor-1 receptor.
Development of a Biomimetic Chondroitin Sulfate-modified Hydrogel to Enhance the Metastasis of Tumor Cells.
Novel Recombinant Protein FlaA N/C Protects against Radiation Injury via NF-κB Signaling.
[Corrigendum] Cannabinoid WIN55, 212-2 induces cell cycle arrest and inhibits the proliferation and migration of human BEL7402 hepatocellular carcinoma cells.
Gamabufotalin, a major derivative of bufadienolide, inhibits VEGF-induced angiogenesis by suppressing VEGFR-2 signaling pathway.
Bezafibrate-mizoribine interaction: Involvement of organic anion transporters OAT1 and OAT3 in rats.
Nicotine Induced Murine Spermatozoa Apoptosis via Up-Regulation of Deubiquitinated RIP1 by Trim27 Promoter Hypomethylation.
IL-17 intensifies IFN-γ-induced NOS2 upregulation in RAW 264.7 cells by further activating STAT1 and NF-κB.
[Correlation between uncoupling protein 2 expression and myocardial mitochondrial injury in rats with sepsis induced by lipopolysaccharide].
Effect of acute lipopolysaccharide-induced inflammation in intracerebroventricular-streptozotocin injected rats.
ApoA-I induces S1P release from endothelial cells through ABCA1 and SR-BI in a positive feedback manner.
Upregulated Expression of microRNA-16 Correlates with Th17/Treg Cell Imbalance in Patients with Rheumatoid Arthritis.
Establishment of a first-line second-line treatment model for human pulmonary adenocarcinoma.
Interaction between endogenous carbon monoxide and hydrogen sulfide in the mechanism of gastroprotection against acute aspirin-induced gastric damage.
Anti-tumor effects of osthole on ovarian cancer cells in vitro.
Casitas B-cell lymphoma (Cbl) proteins protect mammary epithelial cells from proteotoxicity of active c-Src accumulation.
State estimation and prediction using clustered particle filters.
Disrupting MALAT1/miR-200c sponge decreases invasion and migration in endometrioid endometrial carcinoma.
miR-1273g-3p modulates activation and apoptosis of hepatic stellate cells by directly targeting PTEN in HCV-related liver fibrosis.
Kelch-like Protein 21 (KLHL21) Targets IκB Kinase-β to Regulate Nuclear Factor κ-Light Chain Enhancer of Activated B Cells (NF-κB) Signaling Negatively.
MiR-770-5p inhibits cisplatin chemoresistance in human ovarian cancer by targeting ERCC2.
Calcium efflux from the endoplasmic reticulum regulates cisplatin-induced apoptosis in human cervical cancer HeLa cells.
Highly expressed UNC119 promotes hepatocellular carcinoma cell proliferation through Wnt/β-catenin signaling and predicts a poor prognosis.
Study on the Dynamic Biological Characteristics of Sca-1(+) Hematopoietic Stem and Progenitor Cell Senescence.
Liquiritigenin Protects Rats from Carbon Tetrachloride Induced Hepatic Injury through PGC-1α Pathway.
MYBL2 guides autophagy suppressor VDAC2 in the developing ovary to inhibit autophagy through a complex of VDAC2-BECN1-BCL2L1 in mammals.
Panaxadiol Saponin and Dexamethasone Improve Renal Function in Lipopolysaccharide-Induced Mouse Model of Acute Kidney Injury.
The Nucleocapsid Protein of Coronaviruses Acts as a Viral Suppressor of RNA Silencing in Mammalian Cells.
Matrine attenuates focal cerebral ischemic injury by improving antioxidant activity and inhibiting apoptosis in mice.
FUS Interacts with HSP60 to Promote Mitochondrial Damage.
Exposure to airborne PM2.5 suppresses microRNA expression and deregulates target oncogenes that cause neoplastic transformation in NIH3T3 cells.
HBx-related long non-coding RNA DBH-AS1 promotes cell proliferation and survival by activating MAPK signaling in hepatocellular carcinoma.
Olaquindox induces DNA damage via the lysosomal and mitochondrial pathway involving ROS production and p53 activation in HEK293 cells.
Inhibition of migration and induction of apoptosis in LoVo human colon cancer cells by polysaccharides from Ganoderma lucidum.
Establishment and Characterization of Human Germline Stem Cell Line with Unlimited Proliferation Potentials and no Tumor Formation.
A Critical Role for Cysteine 57 in the Biological Functions of Selenium Binding Protein-1.
MicroRNA-206 attenuates tumor proliferation and migration involving the downregulation of NOTCH3 in colorectal cancer.
Reactive stroma component COL6A1 is upregulated in castration-resistant prostate cancer and promotes tumor growth.
Tetrachlorobenzoquinone triggers the cleavage of Bid and promotes the cross-talk of extrinsic and intrinsic apoptotic signalings in pheochromocytoma (PC) 12 cells.
Trophoblast glycoprotein promotes pancreatic ductal adenocarcinoma cell metastasis through Wnt/planar cell polarity signaling.
The safety and anti-hypercholesterolemic effect of coptisine in Syrian golden hamsters.
SPAG6 silencing inhibits the growth of the malignant myeloid cell lines SKM-1 and K562 via activating p53 and caspase activation-dependent apoptosis.
Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice.
Dynamic expression of miR-206-3p during mouse skin development is independent of keratinocyte differentiation.
Cannabinoid WIN55, 212-2 induces cell cycle arrest and inhibits the proliferation and migration of human BEL7402 hepatocellular carcinoma cells.
miR-140-5p regulates adipocyte differentiation by targeting transforming growth factor-β signaling.
Quinolone-indolone conjugate induces apoptosis by inhibiting the EGFR-STAT3-HK2 pathway in human cancer cells.
Postnatal alterations in GABAB receptor tone produce sensorimotor gating deficits and protein level differences in adulthood.
RAD51B Activity and Cell Cycle Regulation in Response to DNA Damage in Breast Cancer Cell Lines.
Inhibition of 15-lipoxygenase (15-LOX) reverses hypoxia-induced down-regulation of potassium channels Kv1.5 and Kv2.1Inhibition of 15-lipoxygenase (15-LOX) reverses hypoxia-induced down-regulation of potassium channels Kv1.5 and Kv2.1.
USP22 promotes the G1/S phase transition by upregulating FoxM1 expression via β-catenin nuclear localization and is associated with poor prognosis in stage II pancreatic ductal adenocarcinoma.
Role of α-lipoic acid in LPS/d-GalN induced fulminant hepatic failure in mice: studies on oxidative stress, inflammation and apoptosis.
Identification and validation of a novel microRNA-like molecule derived from a cytoplasmic RNA virus antigenome by bioinformatics and experimental approaches.
Edwardsiella tarda-Induced cytotoxicity depends on its type III secretion system and flagellin.
Integrative genomics in combination with RNA interference identifies prognostic and functionally relevant gene targets for oral squamous cell carcinoma.
Calpain mediates caspase-dependent apoptosis initiated by hydrogen peroxide in pancreatic acinar AR42J cells.
The hepatitis B virus X protein downregulates NF-κB signaling pathways through decreasing the Notch signaling pathway in HBx-transformed L02 cells.
Limb-girdle muscular dystrophy 1F is caused by a microdeletion in the transportin 3 gene.
Cytohesin-2 as a novel prognostic marker for hepatocellular carcinoma.
Roles of 3,4-methylenedioxymethamphetamine (MDMA)-induced alteration of connexin43 and intracellular Ca(2+) oscillation in its cardiotoxicity.
Yin X, Zhang Y, Zhang Y, Zhou M, Zhang J, Wang Z, Xu W, Song C, Ran J, Lin L, Luo X, Han W
Research (Washington, D.C.) 2026;9:1129
Research (Washington, D.C.) 2026;9:1129
RBM15 Enhances 5-Fluorouracil Drug Sensitivity and Suppresses Gastric Cancer Progression by Modulating N6-Methyladenosine Modification of ECT2-Dependent IGF2BP3.
Zhu X, Chen H, Xu K, Liu Y, Li H, Sang Y, Zhao Y, Liu X, Wang X, Cui X, Cai B, Shang L, Jing C, Chong W, Li L
Research (Washington, D.C.) 2026;9:1108
Research (Washington, D.C.) 2026;9:1108
A Novel Autophagy Inhibitor p-Hydroxylcinnamaldehyde Suppresses Esophageal Squamous Cell Carcinoma by Targeting LDHA Phosphorylation-Mediated Metabolic Reprogramming.
Wei S, Wang J, Zhang Z, Fu Y, Zhao L, Bi Y, Li X, Dai S, Zhang C, Zhu W, Min L, Shan B, Zhao L
Research (Washington, D.C.) 2026;9:1070
Research (Washington, D.C.) 2026;9:1070
Response surface methodology optimization extraction of polysaccharide from Lilium brownii F.E. Brown var. viridulum Baker/Longya Baihe and its biological activities.
Li M, He R, Yang C, Chen H, Wu C, Zhang X, Fu X, Lu C, Yang L, Liu S, Zhang Y
Preparative biochemistry & biotechnology 2026;56(4):593-607
Preparative biochemistry & biotechnology 2026;56(4):593-607
A novel Nilotinib derivative N-12 inhibits the proliferation and migration of colon cancer cells through the EMT signaling pathway.
Jiang Z, Ye X, Song M, Qiao Y, Cheng W, Wang D, Zhang X, Li X, Yu X, Wang X, Ji J, Mou Y
Nucleosides, nucleotides & nucleic acids 2026;45(1):64-87
Nucleosides, nucleotides & nucleic acids 2026;45(1):64-87
Triptonide-mediated PTGS2 Inhibition Induces Autophagic Cell Death to Suppress the Progression of Triple-negative Breast Cancer and Epithelial Ovarian Cancer.
Gong K, Song K, Wang H, Li L, Sun X, Sun L, Hao W, Chen ZS, Huang Y
International journal of biological sciences 2026;22(5):2215-2232
International journal of biological sciences 2026;22(5):2215-2232
NAT10 Promotes Tubular Epithelial Cell Senescence in Cisplatin-Induced Acute Kidney Injury by Regulating DDX17.
Zhu Y, Xu W, Wan C, Deng B, Xie Y, Yang B, Jiang H, Zhang C
International journal of biological sciences 2026;22(4):2177-2195
International journal of biological sciences 2026;22(4):2177-2195
Targeting the LHX1-LDB1 Complex Restores STING-dependent Senescence Surveillance and Inhibits Head and Neck Cancer Progression.
Long M, Chen Y, Du R, Yang J, Wang J, Sun Y, Tian X, Wang S, Zhong Y, Liang W, Zhang J, Shang Z
International journal of biological sciences 2026;22(3):1186-1206
International journal of biological sciences 2026;22(3):1186-1206
DJ-1 alleviates high glucose-induced podocyte injury via activating ERK1/2 signaling.
Tian X, Li J, Han T, Zhang L, Lu P, Liu Y
PloS one 2026;21(4):e0346714
PloS one 2026;21(4):e0346714
A novel SLC20A2 nonsense variant and mechanistic studies of primary brain calcification.
Li Y, Yuan L, Chen H, Zheng W, Xu H, Yang Z, He D, Deng H
PloS one 2026;21(4):e0346635
PloS one 2026;21(4):e0346635
Knockdown of miR-21-5P targets and regulates PDCD4-induced apoptosis in ovarian granulosa cells and ameliorates in sulin resistance in polycystic ovary syndrom.
He H, Ning P, Chen X, Lin J
PloS one 2026;21(3):e0343735
PloS one 2026;21(3):e0343735
Spatholobus suberectus Stem-Derived Extracellular Vesicle-Like Particles Attenuate Glucocorticoid-Induced Osteoporosis via NRF2/HO-1 Signaling.
Chen G, Li H, Chen R, Yao Y, Lian G, Bai L, Chen H, Zhang C, Chen G
International journal of nanomedicine 2026;21:585928
International journal of nanomedicine 2026;21:585928
Hsa_circ_0000313/miR-1224-3p/MKNK2 Axis Modulates CD4(+) T Cells by Activating p38 MAPK Signaling in Myasthenia Gravis.
Li Y, Kong X, Cai H, Tian W, Ren Y, Xu F, Peng S, Niu J, Xin G, Wang J, Zhang H, Wang L
Mediators of inflammation 2026;2026(1):e2877539
Mediators of inflammation 2026;2026(1):e2877539
Dexrazoxane Protects Against Hand-Foot Syndrome-Like Skin Damage in Pegylated Liposomal Doxorubicin-Treated Mice.
Nishida K, Tanaka J, Hashimoto C, Tanaka M, Kuga T, Shigeta S, Kitatani K
Journal of toxicology 2026;2026:1358796
Journal of toxicology 2026;2026:1358796
Cordycepin Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice by Inhibiting IL-6/IL-6R-Mediated p38 MAPK and NF-κB Activation Through Adenosine A(2A) Receptor Stimulation.
Liao Y, Wei W, Qin F, Ruan Y, He T, He J, Wang M, Liu T, Chen J
Drug design, development and therapy 2026;20:575035
Drug design, development and therapy 2026;20:575035
Lactoferrin inhibits anoikis-resistance and metastasis of nasopharyngeal carcinoma cells via the AKT signaling pathway.
Wang Y, Fu Y, Deng X, Xu X, Wu Y, He J, Guo Q, Zou G
International journal of clinical and experimental pathology 2026;19(1):1-13
International journal of clinical and experimental pathology 2026;19(1):1-13
Integrating Single-Cell and Microarray Data to Explore the Role of Autophagy-Related Gene Atg7 in Osteoporosis.
Lin Z, Cheng Y, Tang Q, Zheng H, Li H, Lian Y
Journal of inflammation research 2026;19:579167
Journal of inflammation research 2026;19:579167
FGF7-FGFR2 Signaling Enhances Contractile Activation of CAFs in Ovarian Cancer: Integrative Single-Cell and Spatial Transcriptomics.
Feng S, Ding Z, Wang Y, Zhu Z, Zhong W, Zhang K, Zhang Y, Chen L, Ma Y
Journal of inflammation research 2026;19:571158
Journal of inflammation research 2026;19:571158
Gan-Pi-Tong-Zhi Decoction Ameliorates OVA-Induced Asthma Through MAPK and Nrf2 Signaling Pathways and Regulating Gut Microbiota.
Liu J, Zhao Y, Xu L
Journal of inflammation research 2026;19:570124
Journal of inflammation research 2026;19:570124
Targeting NLRP3 Inflammasome and Metabolic Dysregulation by Electroacupuncture: A Novel Therapeutic Strategy for Methamphetamine Withdrawal-Induced Depression.
Zhang X, Zhao XR, You CL, Zhang F, Zhu HY, Gu T, Li J
ASN neuro 2026;18(1):2624589
ASN neuro 2026;18(1):2624589
The mechanism of Vicenin-2 in ameliorating skin photoaging: involvement of m6A-modified macrophage polarization.
Zhou Y, Shuai W, Peng X, Li R, Chen M, Tan B, Mu Y, Duan X
Frontiers in pharmacology 2026;17:1778993
Frontiers in pharmacology 2026;17:1778993
Integrated multi-omics mapping of the causal landscape of gout across the circulating-tissue axis.
Huang L, Liu J, Zheng X, Zhang K, Chen Y, Chen X, Zhang S, Cai S, Cai L, Guo Y, Zhu P, Li M
Frontiers in immunology 2026;17:1776456
Frontiers in immunology 2026;17:1776456
Electroacupuncture may improve endometrial receptivity in controlled ovarian hyperstimulation mice by activating AVP neurons.
Ma T, Li Q, Li J, Fang Y, Zan Y, Zhuang Y, Zhu Q, Xia L, Xia Y
Frontiers in endocrinology 2026;17:1765673
Frontiers in endocrinology 2026;17:1765673
Licoisoflavone B alleviates psoriasis via SCD1-targeted lipid metabolism reprogramming and suppression of Th17/IL-17-mediated inflammation.
Liu Y, Wong VKW, Liu J, Jiang M, Yang C, He X, Wang J, Zhang L, Xiong A, Ran Q, Li X, Wang K, Li M, Song P, Jin L, Li G
Frontiers in pharmacology 2026;17:1754729
Frontiers in pharmacology 2026;17:1754729
Akkermansia muciniphila alleviates antibiotic- and LPS-induced oxidative stress via the p38α MAPK-Nrf2 signaling axis.
Ye WY, Feng CX, Su SQ, Wei SM, Mao Y, Chen ZY, Su Y, Shan QW
Frontiers in microbiology 2026;17:1753421
Frontiers in microbiology 2026;17:1753421
Ebselen, a promising host-directed therapeutic option against Yersinia pseudotuberculosis infection.
Wu Z, Tang L, Wang Y, Ndong Ella EV, He J, Cheng C, Xiao L, Wang Y, Dong C, Zou L, Wang J
Frontiers in microbiology 2026;17:1749626
Frontiers in microbiology 2026;17:1749626
M2 macrophage-derived exosomes mitigate acute inflammation following ischemic stroke.
Song J, Su G, Chen W, Xie X, Zhang Z
Frontiers in neurology 2026;17:1733679
Frontiers in neurology 2026;17:1733679
Novel prognostic signature unveils PSEN1 contributes to depression-induced lung adenocarcinoma progression.
Zheng Q, Zhuoga J, Li C, Chen W, Yalikun M, Fu P, Dong Z, Dong J
Frontiers in immunology 2026;17:1681306
Frontiers in immunology 2026;17:1681306
CD146(+) pericyte-like lung cancer brain metastatic stem cells promote tumor angiogenesis through dual regulatory effects on the VEGF/VEGFR axis.
Liu W, Duan W, Xia S, Liu Y, Chu H, Liang K, Fang S, Lin M, Wei S, You X, Hu Q, Qi J, Wang Q
Theranostics 2026;16(4):1905-1924
Theranostics 2026;16(4):1905-1924
The D826V point mutation in IREB2 induces lipogenesis in adipose tissues.
Lv Y, Wu C, Xiao J, Yang W, Wang C, Wang J, Huang J, Guo Z, Liao S
Frontiers in cell and developmental biology 2026;14:1724485
Frontiers in cell and developmental biology 2026;14:1724485
SNX1 inhibits human ovarian cancer progression via regulation of the cell cycle, apoptosis and migration.
Li P, Yu X, Wen K, Wang L, Yu J, Chen P
Molecular & cellular oncology 2026;13(1):2604899
Molecular & cellular oncology 2026;13(1):2604899
ESRP1 drives epithelial-mesenchymal transition by activating EPAC-RAP1A signaling axis.
Qi R, Wang J, Cheng G, Zhao T, Hu Z, Yu J, Jia Y, Chen J
Frontiers in medicine 2026;13:1734619
Frontiers in medicine 2026;13:1734619
The NLRP3 inhibitor, MCC950, attenuates environmental pollutant PM(2.5)-induced acute lung injury by inhibiting alveolar macrophage pyroptosis.
Han Z, Han Y, Li R, Fan K, Zhang X, Sun T, Li Y, Qiao H
Current research in toxicology 2026;10:100282
Current research in toxicology 2026;10:100282
Elevated lactate production exacerbates PM2.5-induced pulmonary fibrosis by stabilizing TGF-β1.
Liu Z, Liu W, Wei H, Ping Y, Yu Z, Dong Z, Ren J, Zhang S, Liu S
Journal of advanced research 2026 May;83:299-314
Journal of advanced research 2026 May;83:299-314
Neural stem cell transplantation attenuates cognitive decline and neuroinflammation in a mouse model of Alzheimer's disease with chronic cerebral hypoperfusion.
Lu Z, Zhou H, Tang H, Luo S, Wang J, Zheng X, Hu Y, Qin Q, Yang C, Mo S, Huang X, Tang L, Huang B, Xu W, Nong J, Gan G, Qin D, Peng Z, Jian C, Liu X, Li X, Shang J
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2026 May;46(5):1219-1237
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2026 May;46(5):1219-1237
β-Sitosterol Suppresses Osteoclastogenesis and Alleviates Bone Loss by Targeting Tmed10 to Inhibit RANKL-Induced Hedgehog/MAPK Signaling and ROS.
Huang W, Liu T, Liao J, Lian D, Zeng X, Yao Z, He M, Zhang X, Cai Z
Phytotherapy research : PTR 2026 May;40(5):2491-2513
Phytotherapy research : PTR 2026 May;40(5):2491-2513
Dehydrocorydaline Promotes STAT3/Bcl-2 Axis-Mediated Macrophage Efferocytosis to Attenuate Apoptosis in Atherosclerotic Plaques.
Hongzheng L, Zucheng S, Aimei L, Wenwen Y, Mengfan L, Wenrui J, Wenjing L, Xin Z, Zikai Y, Yingdong L, Zhenpeng Z
Phytotherapy research : PTR 2026 May;40(5):2473-2490
Phytotherapy research : PTR 2026 May;40(5):2473-2490
Influence of Adipose Mesenchymal Stem Cell-Derived Exosomes on the Th2/Treg Cells in Peripheral Blood of the Patients with Allergic Rhinitis and its Mechanism.
Han F, Xu X, Wang Y
American journal of rhinology & allergy 2026 May;40(3):183-190
American journal of rhinology & allergy 2026 May;40(3):183-190
Yeast β-glucan alleviates alcohol-related brain injury by restoring gut-brain axis homeostasis.
Li H, Ouyang Z, Li B, Gong D, Bai J, Li J, Zhang S, Liang Z, Long D
International journal of biological macromolecules 2026 May;360:151880
International journal of biological macromolecules 2026 May;360:151880
Integrated machine learning and experimental validation reveal S6K2 as a key target of 6PPD-quinone in bladder cancer.
Wang J, Lu M, Qi N, Zhang M, Li Z, Li H, Wang J
Ecotoxicology and environmental safety 2026 May;316:120085
Ecotoxicology and environmental safety 2026 May;316:120085
Peroxiredoxin 4 suppresses ferroptosis in esophageal squamous cell carcinoma by activating the phosphoinositide 3-kinase signaling pathway.
Li K, Xu S, Liu H, Fan T, Li Y, Ren R, Xu Y, Li S, Liu Y
Biomedical reports 2026 May;24(5):60
Biomedical reports 2026 May;24(5):60
CYR61 promotes obesity-induced kidney injury by activating endoplasmic reticulum stress.
Li B, Lv H, Gong K, Gao Y, Zhen J, Hu Z
Molecular immunology 2026 May;193:91-102
Molecular immunology 2026 May;193:91-102
Sihe Tufuling formula alleviates imiquimod-induced psoriasis-like skin lesions in mice by modulating the HIF-1 signaling pathway.
Kang Y, Alimujiang A, Zhou F, Chen L, Wang H, Wei W, Zhao J, Zhu Z, Sun W, Xie X, Huo S, Xu D, Li Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158033
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158033
Ubiquitin-Specific Protease 45 Inhibits Lung Adenocarcinoma Ferroptosis by Regulating Ubiquitination and Stability of Glutathione Peroxidase 4.
Huang M, Fang M, Wang Y, Liu S, Li F
Cancer medicine 2026 May;15(5):e71901
Cancer medicine 2026 May;15(5):e71901
Decoding the spatiotemporal development of the blood-brain barrier in human cortex.
Li Z, Li Y, He Z, Wang C, Zhang Y, Li R, Jin L, Jiao J, Ji F, Zhu B, Zhang J, Du P, Dong J, Jiao J
Cell stem cell 2026 May 7;33(5):853-871.e10
Cell stem cell 2026 May 7;33(5):853-871.e10
Emerging roles for SNRPB2 in governing the cell cycle and steering tumor immune modulation in breast cancer.
Zhang J, Wang H, Jia Y, Yasheng A, Ai X, Wang X
Molecular biology reports 2026 May 2;53(1)
Molecular biology reports 2026 May 2;53(1)
Swine GBP1 restricts PDCoV replication via disrupting the replication and transcription complex formation.
Zhang K, Wang S, Kang X, Li F, Zhao Z, Nile W, Zhang C, Shen H, Du S, Kang H, Sun M, Liu Z, Zhang J
Journal of virology 2026 May 19;100(5):e0020726
Journal of virology 2026 May 19;100(5):e0020726
Cytoskeletal protein integrity and its relationship with texture formation and rehydration property of dried fish: biochemical and microstructural evidence.
Peng Y, Ouyang D, Zhou J, Yin S, Rong Z, Li S, Wu J, Wang F, Liu Y, Li X
Food chemistry 2026 May 15;511:148799
Food chemistry 2026 May 15;511:148799
Unleashing T cell surveillance for the eradication of quiescent persister tumor cells resistant to neoadjuvant chemotherapy.
Geng H, Wang H, Zhang C, Zhou Y, Zhong Y, Zhu Z, Wu Z, Zhang T, Xu N, Dong Z, Zhang H, Li Q, Li Y, Tang X, Cheng X, Xia X, Zhang Z, Zhai B, Zheng Z, Li Q, Yang C, Zhu C
Developmental cell 2026 May 13;61(5):995-1011.e12
Developmental cell 2026 May 13;61(5):995-1011.e12
Proteome Profiling Reveals Inflammation and Fibrosis Biomarkers in Urinary Migrasomes of Patients with Diabetic Kidney Disease.
Zhou X, Guo Z, Zhang R, Yan R
Journal of proteome research 2026 May 1;25(5):2344-2358
Journal of proteome research 2026 May 1;25(5):2344-2358
Iron overload reprogramming lipid metabolism through the IRP1-SCAP axis in fibroblast-like synoviocytes aggravates bone destruction in rheumatoid arthritis.
Liu Y, Fang L, Wang M, Zhong S, Xiong Y, Hou Y, Ren J, Li Y, Zhu W, Meng X, Lu C, Pan Y
Experimental & molecular medicine 2026 May 1;
Experimental & molecular medicine 2026 May 1;
Prenylterphenyllin, a regulator of P53, inhibits colorectal cancer progression through oxidative stress and energy metabolism pathway.
Zhang Y, Han Y, Li S, Shan R, Lin L, Gu Z, Wang R, Chen Y, Xiao J, An F, Hu C, He C
Redox biology 2026 Mar;90:103993
Redox biology 2026 Mar;90:103993
S100B induces angiogenesis via the clathrin/FOXO1/β-catenin signaling pathway and contributes to Bevacizumab resistance in epithelial ovarian cancer.
Xu H, Li W, Yue H, Bai Y, Li J, Lu X, Wang J
Journal of advanced research 2026 Mar;81:613-636
Journal of advanced research 2026 Mar;81:613-636
Voxtalisib inhibits enterovirus 71 replication by downregulating host RAN and restoring IFN-STAT signaling.
Wang D, Yang Q, Zhu G, Li Z, Wu C, Hu X, Long G, Wang Q, Chen Y, Xu C, Huang C, Han Y, Zhang D
Journal of advanced research 2026 Mar;81:569-582
Journal of advanced research 2026 Mar;81:569-582
Targeted knockdown of Piezo1 in synovial macrophages attenuates osteoarthritis development.
Yan Z, Wu D, Zhao H, Guan H, Chen J, Huang C, Chen X, Deng X, Hu J, Wang J, Zhang Y
Journal of orthopaedic translation 2026 Mar;57:101053
Journal of orthopaedic translation 2026 Mar;57:101053
The role of nGPx4 in resisting DEHP-induced DNA damage and reducing caspase-independent cell death in male germ cells.
Gu W, Wang J, Liu X, Tan H, Yang H, Zhu Z, Ran P, Ling Q, Mao W
Clinical and experimental reproductive medicine 2026 Mar;53(1):77-96
Clinical and experimental reproductive medicine 2026 Mar;53(1):77-96
ANXA1 overexpression promotes B cell acute lymphoblastic leukemia progression and resistance by regulating fatty acid metabolism through PI3K/Akt signaling.
Liu P, Ma D, Pan C, Kang Q, Wang Y, Zhang M, Wang J
Molecular and cellular biochemistry 2026 Mar;481(3):1401-1414
Molecular and cellular biochemistry 2026 Mar;481(3):1401-1414
Nobiletin and polydatin synergistically alleviate triple-negative breast cancer liver metastasis via suppressing ECM1a-mediated fatty acid biosynthesis.
Wang J, Liu WW, Huang QL, Ning HJ, Wang JY, Han XH
Acta pharmacologica Sinica 2026 Mar;47(3):735-749
Acta pharmacologica Sinica 2026 Mar;47(3):735-749
SAR317461 Inhibit JAK2/STAT3 Phosphorylation for Enhanced Anti-leukemia Activity.
Yang XY, Wang Y, Zhang L, Pang SL, Li XJ, Wang PP, Ma RJ, Ma YY, Song CG
Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion 2026 Mar;42(2):530-541
Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion 2026 Mar;42(2):530-541
Ginsenoside Rb1 Targets the HRD1-STING Axis to Mitigate Cholesterol-Induced VSMC Senescence.
Niu H, Cai Y, Yu C, Lin N, Chen M, Wang L
Journal of clinical laboratory analysis 2026 Mar;40(5):e70172
Journal of clinical laboratory analysis 2026 Mar;40(5):e70172
Rhein attenuates oxidative stress-induced injury in human ovarian granulosa cells by inhibiting the NF-κB-TNF-α/IL-6/PTGS2 inflammatory axis.
Li Y, Qiu J, Zhou Y, Jiang Y, Li X, Weng Y, Chen Y, Lai Y, Yang W
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar;399(6):8113-8129
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar;399(6):8113-8129
Unraveling the Therapeutic Mechanisms of Shanzhen Mingmu Pill in Diabetic Retinopathy: An Integration of Serum Pharmacochemistry, Network Pharmacology, and Experimental Validation.
Yang S, Mo G, Pi X, Xiong T, Cheng L, Meng Y, Hu J, Jiang W, Shi Z
Phytochemical analysis : PCA 2026 Mar;37(2):287-304
Phytochemical analysis : PCA 2026 Mar;37(2):287-304
PDK4-driven lactate accumulation facilitates LPCAT2 lactylation to exacerbate sepsis-induced acute lung injury.
Deng Y, Qiu Y, Li X, Gong T, Guo J, Liang H, Yuan Z, Hei Z, Zhang X, Liu Y
Cell death and differentiation 2026 Mar;33(3):557-573
Cell death and differentiation 2026 Mar;33(3):557-573
Acceleration of Lactate Uptake and Utilization Contributes to Neuroprotective Action of FGF21 Involved in Naturally Aging Mice.
Ji K, Wei H, Wang R, Wu Y, Li C, Gao H, Zhao L
Aging cell 2026 Mar;25(3):e70423
Aging cell 2026 Mar;25(3):e70423
Scutellaria baicalensis extract prevents metabolic dysfunction-associated steatotic liver disease by modulating the gut-liver axis in high-fat diet mice.
Ma L, Wang Y, Ren T, Pan L, Li X, Wang S, Li D, Zhang M, Li F, Zheng F, Yue H
Phytochemistry 2026 Mar;243:114720
Phytochemistry 2026 Mar;243:114720
Anatid herpesvirus 1 UL51 protein is palmitoylated by DHHC9 and DHHC18 for viral replication and virulence.
Liu X, Zhang R, Wang M, Cheng A, Zhang W, Yang Q, Ou X, Sun D, He Y, Tian B, Wu Z, Zhang S, Huang J, Wu Y, Yu Y, Zhang L, Zhao X, Zhu D, Chen S, Jia R, Liu M
PLoS pathogens 2026 Mar;22(3):e1014076
PLoS pathogens 2026 Mar;22(3):e1014076
Vitexin targets USP49-GRPR deubiquitination axis in medullary thyroid carcinoma therapy.
Xia Q, Dong S, Xu W, Lai Q, Song H, Zhang W
Biochimica et biophysica acta. Molecular basis of disease 2026 Mar;1872(3):168128
Biochimica et biophysica acta. Molecular basis of disease 2026 Mar;1872(3):168128
Selenium-Enriched Akkermansia muciniphila: A Novel Probiotic Bacterium for Se Supplementation.
Rui W, Sun Y, Li X, Yang J, Tang X
Probiotics and antimicrobial proteins 2026 Mar;18(2):2639-2653
Probiotics and antimicrobial proteins 2026 Mar;18(2):2639-2653
Betaine supplementation attenuates high-Se induced insulin resistance in C57BL/6 mice.
Wang J, Zhang X, Wang Q, Han F, Xiang X, Huang J, Fang C, Liu Y, Huang Z
The Journal of nutritional biochemistry 2026 Mar;149:110205
The Journal of nutritional biochemistry 2026 Mar;149:110205
XIAP Stabilizes DDRGK1 to Promote ER-Phagy and Protects Against Noise-Induced Hearing Loss.
Yan L, Zhang Y, Du J, Zhu Y, Cao W, Wei Y, Wu H, Qiu S, Pan S, Chen L, Liang P, Chai R, Yang J, Fang Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(18):e11217
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(18):e11217
Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells.
Li J, Zheng H, Lin Y, Zhao Z, Mai Y, Lou Z, Liu Q, Ma Z, Wu C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(18):e10237
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(18):e10237
Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles.
Xie X, Bi S, Su B, Zhou R, Li X, Yan Z, Zhou X, Wang F, Yu T
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(16):e17257
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(16):e17257
FA-2-b-β modulates HMGB1/NF-κB/NLRP3 signaling to alleviate neuroinflammation in Alzheimer's disease.
Zhang Y, Wang J, Yuan J, Li S, Sun Y
Journal of Alzheimer's disease : JAD 2026 Mar;110(2):882-894
Journal of Alzheimer's disease : JAD 2026 Mar;110(2):882-894
Multi-omics mapping identifies CYBA-mediated mitochondrial dysfunction driving macrophage polarization and ferroptosis via Nrf2 pathway in atherosclerosis.
Dong C, Shen R, Pan C, Zhang J, Yu K, Zeng Q
APL bioengineering 2026 Mar;10(1):016107
APL bioengineering 2026 Mar;10(1):016107
Dendritic Cell-Associated MARCKSL1 Regulates Fibroblast Differentiation During Wound Healing.
Takaya K, Nakajima Y, Sakai S, Okabe K, Aramaki-Hattori N, Mori R, Kishi K
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2026 Mar-Apr;34(2):e70143
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2026 Mar-Apr;34(2):e70143
Study on the Mechanism of Paeoniflorin, an Active Component of Paeonia lactiflora Pall., in Improving Skin Pigmentation by Inhibiting the TNF-α Signaling Pathway.
Yin K, Wang S, Wang W, Liu T, Qi D, Wang W, Rashed MMA, Duan H, He C, Zhang M, Liu H, Zhai K
Pharmaceuticals (Basel, Switzerland) 2026 Mar 9;19(3)
Pharmaceuticals (Basel, Switzerland) 2026 Mar 9;19(3)
β-catenin mutation reprograms ketone body metabolism to drive hepatocellular carcinoma metastasis and resistance to ketogenic therapy via transcriptional activation of OXCT1.
Li H, Qian L, Ji Y, Geng Y, Lu Y, Zhang L, Xu Y, Zong W, Jiang X, Zhou X, Wen J, Liu D, Wang Y, Li Y, Li B, Ma H, Yu D
Cell death & disease 2026 Mar 9;17(1)
Cell death & disease 2026 Mar 9;17(1)
Rosmarinic Acid Targets AKR1B1 to Ameliorate Atherosclerosis via Vascular Endothelial Cell Energy Metabolism Regulation.
Sun T, Luo Q, Liu T, Lv X, Lin L, Liao D, Tuo Q, Chen W
Biomolecules 2026 Mar 9;16(3)
Biomolecules 2026 Mar 9;16(3)
Hyaluronic acid-based reduction responsive nanoparticles for Improved anti-psoriasis effects of traditional Chinese herb monomer oleanolic acid via blocking YAP-AREG axis.
Han Y, Ren J, Su Y, Zhou L, Zhu X, Wang Z, Kong F, Li G
Journal of nanobiotechnology 2026 Mar 8;24(1)
Journal of nanobiotechnology 2026 Mar 8;24(1)
Study on the Role of the AMPK/PGC-1α Pathway in Cold-Induced Vascular Endothelial Cell Apoptosis and Uterine Damage.
Bai S, La X, Yang Y, Li Y, Wang D, Ren Y, Fang H, Li X, Song X, Cheng X, Xu D
Biology 2026 Mar 6;15(5)
Biology 2026 Mar 6;15(5)
Genetic variations interact with polybrominated diphenyl ether exposure to alter lipid homeostasis.
Hu N, Li B, Lu Y, Jiang Q, Zhu Y, Li Z, Qu Y, Qiu T, Zhang D, Wang Z, Ma Y, Jin H, Sun P, Song H, Zhao Y, Zhao Y, Zhang M, Zhao F, Ji S, Yuan B, Zhu Y, Lv Y, Tian J, Miao X, Shi X
Nature communications 2026 Mar 5;17(1)
Nature communications 2026 Mar 5;17(1)
Unraveling the Molecular Mechanisms Linking Cigarette Smoke Exposure to Skin Damage.
Tan Z, Wei Y, Zhang S, Song J, Zhu W
International journal of molecular sciences 2026 Mar 4;27(5)
International journal of molecular sciences 2026 Mar 4;27(5)
Dendrobium officinale polysaccharide ameliorate hyperlipidemia through LKB1/AMPK and CD36/PGC-1α/UCP1 activation and gut microbiota modulation.
Gong Y, Fang H, Wu L, Zhang J, Wen Y, Rao Y, Zhao Y
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar 4;
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar 4;
Natural photosynthetic system for restoring homeostasis of animal organelle interaction network.
Xia C, Dai Z, Wang Y, Yu J, Wang Z, Huang Z, Pan K, Yang K, Chen Y, Zhong P, Gu C, Fan S, Lin X, Chen P
Nature communications 2026 Mar 31;17(1)
Nature communications 2026 Mar 31;17(1)
Mechanism of platelet-rich plasma inhibiting inflammatory response, oxidative stress, and senescence in synovial fibroblasts of patients with knee osteoarthritis via UBE2C based on transcriptome sequencing analysis.
Zou L, Ma Y, Hu M, Sun Z, Shi Z, Gao J, Cai X
Journal of bioenergetics and biomembranes 2026 Mar 26;58(1)
Journal of bioenergetics and biomembranes 2026 Mar 26;58(1)
Family single-cell atlases reveal pig pregnancy and fetal growth restriction critical cell types.
Cai L, Zhang Q, Yao T, Zou X, Xie L, Yang S, Xiao Y, Huang F, Peng Z, Yang J, Huang J, Jing Q, Ling Z, Zheng M, Qiao C, Wu J, Chen J, Jiang T, Liu Q, Liu M, Chen Z, Li J, Jiang H, Jiang H, Chen Z, Liao Y, Huang Y, Li L, Zhou Y, Zhang Z, Yin C, Ye Y, Yang H, Chen B, Wang Z, Gong H, Chen D, Huang C, Tong X, Zhou Z, Fu H, Sun Y, Sun X, Yan M, Wu L, Xiong S, Wang Y, Xie X, Zhou M, Liu X, Xie X, Wu F, Liu Z, Ge M, Xiong S, Li C, Shen T, Liu Y, Tang X, Chang X, Liu S, Yu C, Yu N, Hu Z, Cui D, Zhong J, Liu S, Hu J, Wen Y, Zhou W, Wei G, Lin S, Xiahou Y, Chen L, Li J, Liu R, Chen X, Shu Y, Chen F, Wei C, Hu X, Li Y, Hou Y, Zeng Q, Gao J, Su Y, Li J, Ma J, Guo Y, Chen C, Xiao S, Ai H, Zhang Z, Liu W, Yang Q, Xing Y, Rao L, Yang B, Huang L
Science (New York, N.Y.) 2026 Mar 26;391(6792):eadu7265
Science (New York, N.Y.) 2026 Mar 26;391(6792):eadu7265
Meningeal lymphatic dysfunction mediates postoperative sleep deprivation-induced cognitive decline via impaired neuroinflammatory clearance.
Huang B, Tu W, Zhou H, Mo L, Yang Q, Sheng Y, Sun D, Meng B, Chi Z, Lv Y, Liu R, Xing X, Yuan H, Yang J, Hu F, Chen G, Chen J, Chen X, Lu B
Journal of neuroinflammation 2026 Mar 25;23(1)
Journal of neuroinflammation 2026 Mar 25;23(1)
METTL3-regulated m6A modification modulates autophagy of placental mesenchymal stem/stromal cell by YTHDF3-mediated degradation of LncRNA GAS5 in preeclampsia.
Zhang Y, Wu D, Zou L, Cheng X, Liu X
Placenta 2026 Mar 25;176:31-42
Placenta 2026 Mar 25;176:31-42
A new candidate tumor suppressor tRF-Ser inhibits gastric cancer progression by regulating the CNBP/HSPA8 axis.
Jiao J, Wang G, Liu J, Xiao K, Gao Z, Dong D, Shan K, Cui H, Shang L, Li L, Zhang C
Cell death & disease 2026 Mar 25;17(1)
Cell death & disease 2026 Mar 25;17(1)
GALNT1 emerges as a potential therapeutic target in breast cancer.
Li J, Zhong P, Li X, Huang R, Zhan Z, Li J, Mao M
Journal of cancer research and clinical oncology 2026 Mar 25;152(3)
Journal of cancer research and clinical oncology 2026 Mar 25;152(3)
FASN inactivation-induced progranulin (GRN) expression promotes lysosome-dependent cell death to suppress leukemogenesis.
Su M, Li Q, Lv Z, Xie X, Lu Y, He Y, Liu H, Cao H, Ouyang J, Zhang Q, Ma X, Yang Y, Zou A, Liu K, Xu S, Li J, Chen L, Lu X, Yang J, Wu C, Liu L, Zhang L, Sheng Y, Huang Y, Mei Y
Cell reports 2026 Mar 24;45(3):117042
Cell reports 2026 Mar 24;45(3):117042
Matrix Stiffness Modulates Fibroblast Paracrine Signaling to Enhance Autophagy in Keratinocytes: Implications for Wound Healing.
Chen Y, Gao X, Liu Y, Li W, Cai X
ACS omega 2026 Mar 24;11(11):17605-17616
ACS omega 2026 Mar 24;11(11):17605-17616
Phytosterol alleviates cholesterol accumulation by influencing intestinal esterification rather than competitive solubilization under dietary MUFA.
Zhao T, Zhang Y, Wang Z, Yin J, Nie S, Jiang Y, Sun C, Lu B
Journal of advanced research 2026 Mar 22;
Journal of advanced research 2026 Mar 22;
High-Intensity Interval Training Outperforms Moderate-Intensity Exercise in Hyperlipidemic ApoE⁻/⁻ Mice: A Molecular and Histological Comparison.
Qian C, Pei Z, Yang Z, Sun M, Zhang Y, Liu H, Sun Y
Frontiers in bioscience (Landmark edition) 2026 Mar 20;31(3):47751
Frontiers in bioscience (Landmark edition) 2026 Mar 20;31(3):47751
CCT3-mediated regulation of XPO1/RB1 axis stability promotes cellular senescence and tumor progression in clear cell renal carcinoma.
Cao Y, Xu C, Liu Y, Shi B, Li X, Li J, Zhang B, Zhang Z, Dai S, Sun Q, Gu J
iScience 2026 Mar 20;29(3):114840
iScience 2026 Mar 20;29(3):114840
PCMTD1-127aa suppresses osteosarcoma progression by competitively binding to USP10 to promote c-MYC degradation.
Li A, Wang S, Li F, Xiong X, Liu N, Xie X, Yao G, Liu Z, Yan M, Yang F
iScience 2026 Mar 20;29(3):114765
iScience 2026 Mar 20;29(3):114765
Ferulic Acid Alleviates Chemotherapy-Induced POI by Targeting the Grp78 and Perk-eIF2α-ATF4-CHOP Pathway to Attenuate Endoplasmic Reticulum Stress.
Li F, Huang Y, Liu Z, Geng Y, Hu R, Song Y, Xu L, Zhang M
Biomedicines 2026 Mar 19;14(3)
Biomedicines 2026 Mar 19;14(3)
Pathological Characteristics of the Lung and Brain in Cotton Rats and BALB/c Mice Infected with Respiratory Syncytial Virus.
Wang Z, Jiang B, Huang Z, Liu M, Li Z, Long W, Shen H, Fan S, Ye Y, Huang Z
Viruses 2026 Mar 18;18(3)
Viruses 2026 Mar 18;18(3)
Hijacking Actin-Pre-Liquid-Liquid Phase Separation Suppresses Malignant Tumor Invasion and Growth.
Zhang Z, Yin K, Li B, He H, Bai Y, Zheng B
Journal of the American Chemical Society 2026 Mar 18;148(10):10561-10584
Journal of the American Chemical Society 2026 Mar 18;148(10):10561-10584
LINC01996 suppresses non-small cell lung cancer proliferation and metastasis by orchestrating the miR-12115/CNRIP1/Ras signaling axis.
Zhang Y, Li X, Liu S, Xue Q, Meng P, Ge X, Zhao Q, Ma H
Clinical & experimental metastasis 2026 Mar 17;43(2)
Clinical & experimental metastasis 2026 Mar 17;43(2)
Charge-Adaptive Nanoparticle Attenuates Inflammation via Targeting Neutrophil Extracellular Traps (NETs) and Breaking NETs-Macrophage Crosstalk.
Chen Y, Lei R, Guo Q, Liu K, Cheng H, Yu S, Li Y, He P, Yang S
ACS nano 2026 Mar 17;20(10):8936-8957
ACS nano 2026 Mar 17;20(10):8936-8957
Ezrin, radixin, and moesin are novel citrullinated proteins in the decidua during pregnancy†.
Yamashita K, Ito S, Satoh J, Takaori-Kondo A, Mizugishi K
Biology of reproduction 2026 Mar 16;114(3):1018-1029
Biology of reproduction 2026 Mar 16;114(3):1018-1029
Programmable RNA N(6),2´-O-Dimethyladenosine Editing.
Li Y, Tan X, Liu Y, He Y, Yuan B, Wang P, Ma G, Guo M, Zhou J, Sun Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 13;:e74815
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 13;:e74815
Endogenous Ceramide 24:1 Constrains Th17-Driven Neutrophilic Inflammation by Antagonizing EP2 Signaling.
Liu H, Aili A, Kuang Z, Cao L, Li Z, Shang Y, Ge Y, Hu T, Sun Y, Zhao W, Jin R, Chang C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 13;:e20695
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 13;:e20695
Protective Effect of Paeoniae Radix Alba Carbonisata on Hepatic Amyloidosis by Regulating Calcium Homeostasis.
Liu G, Wang Z, Xu H, Jia J, Xue Z, Ge W, Ji X, Cui L, Huang Y
International journal of molecular sciences 2026 Mar 11;27(6)
International journal of molecular sciences 2026 Mar 11;27(6)
Acrylamide exposure induces neurotoxicity via the PI3K/Akt/NF-κB pathway: Evidence from network toxicology and experimental validation.
Duan Z, Yu C, Yu Q, Yang W, Zhang R, Ruan Q, Zhao Y, Yan S
Ecotoxicology and environmental safety 2026 Mar 1;312:119922
Ecotoxicology and environmental safety 2026 Mar 1;312:119922
Polystyrene nanoplastics trigger mitochondrial and metabolic reprogramming in cardiomyocytes: Evidence from integrated transcriptomic and metabolomic analysis.
Zhang H, Cao H, Luo Y, Cao Y, Meng X, Wang X, Du R, Yan X, Gao Y, Fang Z, Liu M
Ecotoxicology and environmental safety 2026 Mar 1;312:119921
Ecotoxicology and environmental safety 2026 Mar 1;312:119921
Therapeutic effects of low-intensity transcranial focused ultrasound stimulation on ischemic stroke in rats: An in vivo evaluation using electrical impedance tomography.
Guo J, He S, Yan L, Wang L, Shi X, Hu H, Li L
Neural regeneration research 2026 Mar 1;21(3):1183-1190
Neural regeneration research 2026 Mar 1;21(3):1183-1190
USP52 promotes clear cell renal carcinoma progression by deubiquitinating and stabilizing CORO6.
Wang X, Zhang N, Bu Y, Zhang Y, Wang X, He X, Zhuang X, Zong Q, Zhou B, Luo G
Translational oncology 2026 Jun;68:102773
Translational oncology 2026 Jun;68:102773
Melanocyte proliferation gene 1 regulated metabolic reprogramming in acute myocardial infarction based on the AMPK/mTOR pathway.
Zhu S, Qu T, Liu Z, Gao Y, Chang X, Yu H
Toxicology and applied pharmacology 2026 Jun;511:117797
Toxicology and applied pharmacology 2026 Jun;511:117797
Hyperoside impairs mitochondrial respiration in chronic myeloid leukemia by promoting STUB1-mediated ubiquitination and degradation of NOX4.
Che H, Zhao B, Yi W, Liu P, Hu L
Toxicology and applied pharmacology 2026 Jun;511:117795
Toxicology and applied pharmacology 2026 Jun;511:117795
Nicotine Activates PI3K/AKT Pathway to Induce Cellular Proliferation, Invasion, and Migration in HPV-16 Positive Cervical Cancer SiHa Cells.
Wang J, Hu Y, Gong J, Chen L, Zhang L, Wang H
Journal of applied toxicology : JAT 2026 Jun;46(6):2077-2089
Journal of applied toxicology : JAT 2026 Jun;46(6):2077-2089
Haizao Yuhu Decoction Inhibits Goiter via p53 Pathway-Induced Apoptosis: Metabolomic and Cellular Assay Analysis.
Liu X, Liao W, Xu X, Wu M, Zhang J, Wu Y, Chen S, Liu H, Zhang S, Xiu L, Zhong G
Biomedical chromatography : BMC 2026 Jun;40(6):e70452
Biomedical chromatography : BMC 2026 Jun;40(6):e70452
Untargeted Metabolomic Study of the Anti-HBV Effects of Erythrocentaurin In Vitro and In Vivo Using UPLC-Q-TOF/MS.
Wang Y, Tang S, Li P, Sun Y, Xu Y, Li H, Xu H, Wang Y, Zhang H, Li X, Wang Z
Biomedical chromatography : BMC 2026 Jun;40(6):e70447
Biomedical chromatography : BMC 2026 Jun;40(6):e70447
Unveiling the prognostic and immunotherapeutic role of Tregs in lung cancer using integrated analysis of single-cell and bulk RNA-sequencing.
He H, Xiao Z, Xue J, Zhang Y, Qu J, Wu P, He Q
Oncology letters 2026 Jun;31(6):233
Oncology letters 2026 Jun;31(6):233
Aldh3a1-mediated detoxification of reactive aldehydes contributes to distinct muscle responses to amyotrophic lateral sclerosis progression.
Li A, Dong L, Li X, Yi J, Wu JY, Ma J, Zhou J
Free radical biology & medicine 2026 Jun;249:469-488
Free radical biology & medicine 2026 Jun;249:469-488
Glutathione-depleting mitochondria-targeting nanodrugs for stress amplification and immune activation via synergistic photodynamic therapy and cuproptosis.
Zhang P, Lin H, Guan Q, Xiong S, Tian Z, Wu W, Dai T, Wang X, Ruan J, Yang S, Dou H
Acta biomaterialia 2026 Jun;216:389-402
Acta biomaterialia 2026 Jun;216:389-402
Urinary exosomes aggravate diabetic kidney disease by inducing podocyte ferroptosis via the miR-217/SIRT1/Nrf2 pathway.
Du X, Jiang Y, Guo H, Zhang H, Wang S, Deng H, Huang X, Li X
Journal of cell communication and signaling 2026 Jun;20:e70076
Journal of cell communication and signaling 2026 Jun;20:e70076
Atractylenolide I ameliorates acute-on-chronic liver failure (ACLF) by promoting autophagy and preserving mitochondrial function through mTOR inhibition.
Tang D, Tuo F, Chen J, Ding L, Wu YN, Wang R
Biochimica et biophysica acta. Molecular basis of disease 2026 Jun;1872(5):168197
Biochimica et biophysica acta. Molecular basis of disease 2026 Jun;1872(5):168197
Tannic acid inhibits viral replication by disrupting nucleocapsid condensation.
Pan J, Jiang SZ, Zhu Y, Li XW, Yu LB, Wang Z, Shen BL, Luo RB, Fan LJ, Yu Y, Qian BS, Wang ZJ, Liu Y, Cai H, Xue W, Xia T, Han QY, Wang K, Xu X, He XH, Chen Y, Gao Y, Li AL, Li T, Zhang R, Zhao M, Zhou T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158151
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158151
Scutellarin modulates Nrf2 to alleviate inflammation, pyroptosis, and ferroptosis in acetaminophen-induced hepatotoxicity.
Pu R, Cui Q, Xing Z, Liu L, Xiao W, Xiao Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158107
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158107
Echinacoside modulates PARP14-GLUD1 axis to mediate energy metabolism reprogramming and mitochondrial function in diminished ovarian reserve.
Liang H, Shu C, Huang Z, Yuan S, Yang Q, Chen S, Zhou X, Yang N, Xiang X, Xia Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158100
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158100
Astragaloside IV alleviates post-traumatic cytotoxic edema via inhibition of AQP4 expression and subcellular localization.
Shen W, Jiang C, Liu X, Wang D, Li G, Hui Y, Ding Y, Li C, Shao B, Hou B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158096
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158096
XIAOSHUI formula inhibits malignant pleural effusion by targeting the STC1/p65/CXCL5 axis to reprogram tumor-associated macrophages.
Ge S, Qi R, Zhang Y, Zhao Y, Wei J, Huang Q, Liu F, Miao X, Hua B, Liang J, Jiang S, Shi Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158072
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158072
Paeonol inhibits the progression of endometrial cancer by affecting TRIM26-mediated LDHA ubiquitination modification.
Chen X, Liu J, Liang Y, Gong Z
Tissue & cell 2026 Jun;100:103359
Tissue & cell 2026 Jun;100:103359
Salvianolic acid C, a novel pyroptosis inhibitor, attenuates podocyte injury in diabetic kidney disease through regulating miRNA-21/A20 pathway.
Xiang S, Shi X, Lv M, Gao G, Wang P, Ma H, Xu J, Xie Z, Zhang X, Li G
Journal of ethnopharmacology 2026 Jun 28;365:121589
Journal of ethnopharmacology 2026 Jun 28;365:121589
Design, synthesis, and pharmacological evaluation of novel PROTAC degraders targeting 11β-HSD1 for metabolic disease intervention.
Wang L, Tao X, He M, Lu Y, Wang Y, Zhu J
Bioorganic chemistry 2026 Jun 15;174:109731
Bioorganic chemistry 2026 Jun 15;174:109731
Integrated network pharmacology and AlphaFold modeling reveal ESR1 as a key target of Huanglian Jiedu decoction for ameliorating sepsis-induced coagulopathy.
Yiming S, Bing S, Yinghao P, Haiyi D, Suzhen Z, Qiuhua C, Linfeng D, Weinan W, Lu C, Xiaowen Z, Yuanyuan G, Xing W, Hua J
Journal of ethnopharmacology 2026 Jun 12;364:121529
Journal of ethnopharmacology 2026 Jun 12;364:121529
Tibetan medicine Bawei Chenxiang Wan attenuates chronic mountain sickness by targeting the AKT/FOXO3a/CAT axis to inhibit oxidative stress.
Li X, Zhang S, Qiu Y, Wang Y, Hou J, Ji X, Ge F, Zhang X, Sun Q, Song H, Ciwang R, Luo Y, Tao X
Journal of ethnopharmacology 2026 Jun 12;364:121481
Journal of ethnopharmacology 2026 Jun 12;364:121481
Role of PTP1B in coordinating synaptic plasticity and ferroptosis: A mechanism underlying the antidepressant effect of spinosin from Ziziphus jujuba Mill. var. spinosa (Bunge) Hu ex H. F. Chou.
Wang Y, Zhang Y, Wang J, Wu X, Li Y, Sun W, Song L, Gong M, He Q, Qin L, Wang Q, Ji L, Zhang T
Journal of ethnopharmacology 2026 Jun 12;364:121428
Journal of ethnopharmacology 2026 Jun 12;364:121428
ACOT8-mediated palmitate accumulation promotes M1 macrophage polarization in renal ischemia-reperfusion injury via activation of the cGAS-STING pathway.
Zhang H, Liu X, Ji X, Zhang G, Wang B, Xiong F, Sun D, Wang C
International immunopharmacology 2026 Jun 1;178:116558
International immunopharmacology 2026 Jun 1;178:116558
Neferine ameliorates psoriasis through inducing oxidative stress-mediated keratinocyte apoptosis and suppressing inflammatory response via the Keap1-Nrf2 pathway.
Cheng B, Zhang Z, Bai R, Du W, Le H, He K, Yin T, Wang Z, Liu X, Liu J, Zheng Y
Free radical biology & medicine 2026 Jul;250:517-534
Free radical biology & medicine 2026 Jul;250:517-534
Propyl gallate mitigates diabetic liver injury via suppressing SLC7A11/GPX4-mediated hepatic ferroptosis and modulating gut-liver axis.
Zhang Z, Jiao S, Wang H, Chen Y, Zhang Z, Zhang Y, Gao R, Xiao Y, Liu Y, Zhu Y, Zhu G, Guo J
Biochemical pharmacology 2026 Jul;249:117926
Biochemical pharmacology 2026 Jul;249:117926
Endothelial Foxp1 overexpression inhibits endothelial-to-mesenchymal transition via suppressing Notch pathway activation to attenuate valvular calcification in chronic kidney disease.
Wang X, Ding W, Wei C, Guan C, Zhang N, Xu L, Tang R, Xu Y, Wang L
Biochemical pharmacology 2026 Jul;249:117901
Biochemical pharmacology 2026 Jul;249:117901
Primase subunit 2 regulates the proliferation and apoptosis of gastric cancer cells via MCM7/CDK4 and Bax/Bcl-2 pathways.
Liu B, Wang X, Wang Y, Zhang T, Guo R, Chen X, Zhang Z
Biochimica et biophysica acta. General subjects 2026 Jul;1870(7):130947
Biochimica et biophysica acta. General subjects 2026 Jul;1870(7):130947
Design, synthesis and biological evaluation of testosterone derivatives as potential anti-tumor and anti-inflammatory agents.
Hou X, Wang H, Guo J, Wang J, Yang J, Liu L
Bioorganic chemistry 2026 Jul 5;175:109777
Bioorganic chemistry 2026 Jul 5;175:109777
Microglial efferocytosis dysfunction contributes to depression-like behaviors and cognitive impairment in aged mice following chronic sleep deprivation.
Wang M, Zhu X, Han W, Deng S, Wei H, Yu M, Xu Y
Journal of affective disorders 2026 Jul 15;405:121566
Journal of affective disorders 2026 Jul 15;405:121566
Abnormal FKN-CX3CR1-NR signal triggers hippocampal synaptic dysfunction in rheumatoid arthritis-related depression.
Yao SX, Luo SY, Zhao HQ, Tan H, Liu PA, Liu J
International immunopharmacology 2026 Jul 15;181:116693
International immunopharmacology 2026 Jul 15;181:116693
Pyrimethamine regulates m6A modification of CCND1 via METTL14/YTHDF2 to inhibit hepatocellular carcinoma.
Han X, Wang K, Liu C, Yin S, Shao Y, Zhang J, Wang D, Pan G, Yu H
Bioorganic chemistry 2026 Jul 15;176:109892
Bioorganic chemistry 2026 Jul 15;176:109892
Characterization of a polysaccharide from Rhodobryum giganteum and its activation effects on TLR4/PI3K-Akt/IκBα pathway.
Geng JM, Zhu PF, Xu LS, Liu JL, Yang ZQ, Yang ZY, Jin Q, Liu L
Carbohydrate polymers 2026 Jul 1;383:125319
Carbohydrate polymers 2026 Jul 1;383:125319
Role of AQP1 in the Ameliorating Effect of Electroacupuncture in a Rodent Model of Visceral Hypersensitivity.
Li L, Xu L, Wang L, Sun Y, Ran Y, Mei L, Zhuang Y, Zhang X, Ye F, Dai F
Digestive diseases and sciences 2026 Jan;71(1):155-171
Digestive diseases and sciences 2026 Jan;71(1):155-171
6-Gingerol alleviates NNK-induced lung carcinogenesis by boosting antioxidation and reducing inflammation.
Qu Z, Ding Y, Zhang L, Sun J, Wang T, Zhuang C
Free radical research 2026 Jan;60(1):1-15
Free radical research 2026 Jan;60(1):1-15
Disruption of the nucleocapsid-RNA condensation by punicalagin is a broad-spectrum antiviral approach.
Jiang SZ, Yu LB, Shen B, Pan J, Li XW, Luo RB, Fan LJ, Qian BS, Zhu Y, Wang Z, Liu Y, Li T, Zhang XR, Yu Y, Xue W, Xia T, Cai H, Han QY, Wang K, Xu X, Zhang R, Zhang XM, Li AL, Zhou T, Gao Y, Zhao M, Li T
Fundamental research 2026 Jan;6(1):535-547
Fundamental research 2026 Jan;6(1):535-547
Exploring the role of metformin in high fluoride ingestion-induced bone lesions.
Xu W, Jiang N, Zhang Z, Xu H
Toxicology and applied pharmacology 2026 Jan;506:117653
Toxicology and applied pharmacology 2026 Jan;506:117653
LRRC8A Mediates Ischemic Neuronal Injury by Potentiating NMDA Receptor Activity and Activating Mitochondrial Apoptotic Pathway.
Qian C, Huang L, Chen Y, Lv J, Wang Z, Dai J, Luo Y
Cell biology international 2026 Jan;50(1):e70118
Cell biology international 2026 Jan;50(1):e70118
Cyprinid Herpesvirus 2 Infection Activates IL-17C/NF-κB/IFNγ Antiviral Signalling Axis in Caudal Fin Cells of Carassius auratus Gibelio.
Xie Y, Zhang X, Li F, Lu L
Journal of fish diseases 2026 Jan;49(1):e70017
Journal of fish diseases 2026 Jan;49(1):e70017
Aspirin's therapeutic mechanism against diesel particulate matter-induced lung injury revealed by network pharmacology and experimental models.
Zhang Y, Li B, Cao H, Gao J, Wang T, Chen Q, Tao X
Drug and chemical toxicology 2026 Jan;49(1):205-215
Drug and chemical toxicology 2026 Jan;49(1):205-215
USP28 Promotes Osimertinib Resistance in H1975 NSCLC Cells by Deubiquitinating and Stabilizing SIRT1.
Fan HS, Li XM, Gu JQ, Wang HF, Zhang ZJ
The Kaohsiung journal of medical sciences 2026 Jan;42(1):e70095
The Kaohsiung journal of medical sciences 2026 Jan;42(1):e70095
m6A-Modified BASP1 Regulates IL6 Expression to Induce TAM Infiltration to Promote Gastric Cancer Progression.
Liu G, Liu Y, Zhao H, Sun J, Yang H, Ding Q
Journal of gastroenterology and hepatology 2026 Jan;41(1):189-201
Journal of gastroenterology and hepatology 2026 Jan;41(1):189-201
Metformin alleviates presbycusis by activating the SIRT1/PINK1/GPX4 pathway in vitro and in vivo.
Zeng C, Lin W, Gu X, Chen X, Lin Y, Chen Y, Chen Z, Lin C
Inflammopharmacology 2026 Jan;34(1):729-741
Inflammopharmacology 2026 Jan;34(1):729-741
Targeting aldose reductase in pulmonary fibrosis: Blocking de novo fatty acid synthesis halts pro-fibrotic M2 polarization.
Li J, Zhang Q, Zhao P, Mei X, Shi Y, Shao W, Yu X
International journal of biological macromolecules 2026 Jan;337(Pt 2):149590
International journal of biological macromolecules 2026 Jan;337(Pt 2):149590
Glutamine modified lipid nanoparticles loaded with GPX4 siRNA for cervical cancer targeting.
Chen Y, Zhong L, Chen J, Li X, Lv J, Chen H, Ran R
International journal of biological macromolecules 2026 Jan;336:149419
International journal of biological macromolecules 2026 Jan;336:149419
Intermittent Fasting Alleviates Anesthesia/Surgery-Induced Delirium-Like Behavior in Aged Mice by Remodeling Gut Microbiota.
Huang P, Cao L, Cao T, Wang X, Cui S, Jiang S, Chen H, Di L, Li S, Huang L
CNS neuroscience & therapeutics 2026 Jan;32(1):e70748
CNS neuroscience & therapeutics 2026 Jan;32(1):e70748
Kaempferol Mitigates CSE-Induced Lung Injury and Epithelial Cell Ferroptosis via Modulating Nrf2/NCOA4/GPx4 Axis.
Jin F, Xing Y, Li S, Yi Z, Wu A, Li X
Journal of cellular and molecular medicine 2026 Jan;30(1):e71010
Journal of cellular and molecular medicine 2026 Jan;30(1):e71010
ATF4 transcriptional regulation of OMD and STC2 drives vascular calcification progression via the PI3K/AKT pathway.
Yue Z, Wang MY, Yuan CZ, Xu JW, Shao KK
Pathology, research and practice 2026 Jan;277:156296
Pathology, research and practice 2026 Jan;277:156296
Transcriptomic profiling reveals the role of Hedgehog signaling as a biomarker and in the pathogenesis of Ménétrier's disease.
Shin M, Gabriel TT, Ofosu FK, Zhang J, Wang TT, Bechard ME, Coffey RJ, Huh WJ
The Journal of pathology 2026 Jan;268(1):65-76
The Journal of pathology 2026 Jan;268(1):65-76
Systemic LINE-1 RNA in Plasma Extracellular Vesicles Drives Neuroinflammation and Cognitive Dysfunction via cGAS-STING Pathway in Aging.
Yu S, Cheng Q, Yu Q, Cui Z, Chen H, Wu S, Jin Y, Wang Y, Li M, Lu Z
Aging cell 2026 Jan;25(1):e70350
Aging cell 2026 Jan;25(1):e70350
CDX2 Promotes Hepatic Specification of hiPSC-derived Endoderm Through the PI3K-Akt-GSK3β Pathway for Improved Therapeutic Efficacy.
Bai F, Duan J, Yang D, Lai X, Ji H, Zhu X, He X, Hu A
Stem cell reviews and reports 2026 Jan;22(1):503-522
Stem cell reviews and reports 2026 Jan;22(1):503-522
Thallium exposure disturbs gut microbiota composition, metabolic function, and host gut energy metabolism in aged mice.
Yao H, Su Q, Dai Q, Li L, Li D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 Jan;207:115793
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 Jan;207:115793
Zinc Deficiency Aggravates High-Fat Diet-Induced Renal Injury by Regulating Oxidative Stress and Inflammation via the Nrf2/HO-1 Pathway.
Guan Y, Wu L, Wu M, Zhu Y, Luo P, Luo M
Biological trace element research 2026 Jan;204(1):60-73
Biological trace element research 2026 Jan;204(1):60-73
Verticinone inhibits cell growth and induces pyroptosis via regulating AKT pathway in papillary thyroid cancer.
Liu X, Liu Y
Molecular immunology 2026 Jan;189:41-52
Molecular immunology 2026 Jan;189:41-52
Unraveling the active ingredients and molecular mechanisms of Qinghua Changyan granule against irritable bowel syndrome with diarrhea: Effects on gut microbiota and glutamine transport via an integrative approach combining UHPLC-MS/MS and experimental verification.
Yang J, Wang Y, Wang S, Liu Z, Chen X, Jia R, Wang J, Wang F, Yang Q, Tang L, Miao W
Fitoterapia 2026 Jan;188:106960
Fitoterapia 2026 Jan;188:106960
Isomeranzin activates Gnas-AMPK signaling to drive white adipose browning and curb obesity in mice.
Shi M, Ye Y, Hu L, Yan Y, Jiang S, Wang P, Li F, Ai M, Huang J, Yang L, Huang K, Liang M
EMBO molecular medicine 2026 Jan;18(1):55-90
EMBO molecular medicine 2026 Jan;18(1):55-90
Pharmacological inhibition of PGK1 by genipin reduces inflammation and oxidative damage in osteoarthritis.
Li M, Peng Y, Xiao Q, Chen S, Zhang C, Chen H, Zhao Y, Chang S, Qiu L, Zhang L, Guo X, Fu Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157729
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157729
Ononin promotes bone marrow-derived mesenchymal stem cells survival via SIRT6/Nrf2 signaling for myocardial infarction repair.
Hu C, Xu T, Xu H, Pang M, Zhang G, Han X, Zhang J, Liu M, Hua Y, Chen G, Zhong B, Deng B, Tu Y, Chen T, Hu S, Liu B, Zhou Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157514
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157514
Qingqi Liangying formula inhibits brain endothelial cell pyroptosis via NLRP3/caspase-1/GSDMD in sepsis-associated encephalopathy.
Song S, Ding L, Huang Q, Zhang Z, Cao L, Yin K, Wang Z, Zhao D, Wang Z, Zhao L, Tong X, Li X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157391
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157391
Carnosic Acid Mediates Production of Reactive Oxygen Species to Regulate Mitogen-Activated Protein Kinase Pathway Phosphorylation and Induce Apoptosis in Human Breast Cancer Cells.
Wang X, Xu P, Luan S, Jiao Y, Gao Y, Zhao C, Fu P
Cancer medicine 2026 Jan;15(1):e71446
Cancer medicine 2026 Jan;15(1):e71446
Batatasin III alleviates slow transit constipation by regulating gut microbiota and inhibiting the NLRP3-IL-1β pathway.
Yin F, Jiang Z, Tong Y, Wang S, Zheng K, Han L, Ma W, Li R, Dou X, Ping Y, Wu B, Fu L, Sun D
The Journal of nutritional biochemistry 2026 Jan;147:110110
The Journal of nutritional biochemistry 2026 Jan;147:110110
REEP1 Accumulation Disrupts ER Integrity and Drives Spinal Motoneuron Degeneration in Distal Hereditary Motor Neuropathy.
Bock A, Schurig M, Willoughby M, Mirecki A, Seemann E, Lohachova K, Katona I, Mittag S, Liebmann L, Franzka P, Heidari Horestani M, Khundadze M, Mosler T, Louie T, de Visser M, Weterman MAJ, Kiehntopf M, Beetz C, Nietzsche S, Huber O, Weis J, Kessels MM, Bhaskara RM, Qualmann B, Đikić I, Hübner CA
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(2):e11483
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(2):e11483
Inhibiting Liver-Derived C3 Protein Rescues Anesthesia/Surgery-Induced Cognitive Impairment, Synaptic Disorders, and Microglial Phagocytosis.
Wu Q, Cong P, Li Z, Zhang Y, Wu H, Zhang Q, Li Y, Tian L, Miao Q, Zheng Y, Zhang H, Chen Q, Feng E, Li X, Chen Z, Wang DX, Huang X, Xiong L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(2):e02034
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(2):e02034
ZDHHC2-Dependent Palmitoylation Dictates Ferroptosis and Castration Sensitivity in Prostate Cancer via Controlling ACSL4 Degradation and Lipid Peroxidation.
Shao S, Li W, Hong Y, Zeng R, Zhu L, Yi L, Li Y, Wang Y, Huang H, Jiang X, Jin X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(1):e14077
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(1):e14077
Renal-targeted exosomes inhibiting miR-182-5p for treatment of renal ischemia-reperfusion injury.
Li Z, Sun S, Zhao Z, Guo Y, He Q, Yang M, Zheng J, Li J, Xue W, Ding C
Bioengineering & translational medicine 2026 Jan;11(1):e70081
Bioengineering & translational medicine 2026 Jan;11(1):e70081
Rhapontigenin alleviates cellular senescence and physiological aging by upregulating sirt1 and promoting autophagy.
Liu S, Chen W, Xu G, Liu X, Shi Y, Wang G, Ning Y, Cao Y, Li M, Zhao Y
Chinese medicine 2026 Jan 9;21(1):22
Chinese medicine 2026 Jan 9;21(1):22
RNA-coupled CRISPR screens reveal ZNF207 as a regulator of LMNA aberrant splicing in progeria.
Behera AK, Kim JJ, Kordale S, Pekovic F, Damodaran AP, Kumari B, Vidak S, Dickson E, Xiao MS, Duncan G, Andresson T, Misteli T, Valkov E, Gonatopoulos-Pournatzis T
Molecular cell 2026 Jan 8;86(1):41-59.e15
Molecular cell 2026 Jan 8;86(1):41-59.e15
Acupuncture ameliorates diet-induced obesity via the vagal-GLP-1-ARC circuit: neural mechanism of anorexigenic action.
Yang Y, Shao Y, Tian J, Wang Y, Zhu Y, Pan S, Wei X, Jiang L, Wang X, Shu Q
Chinese medicine 2026 Jan 8;21(1):20
Chinese medicine 2026 Jan 8;21(1):20
Time-resolved multiomics profiling reveals chromatin O-GlcNAc modification promotes senescence-associated transcriptional program.
Zhang N, Zhao R, Zhong X, Dong Q, Liu Y, Yu K, Han L, Meng F, Wu J, Chen Q, Li X, Chen Q, Zhang K, Huang H, Zhang J, Wu S, Ren Y, Wang W, Liu Y
Nature communications 2026 Jan 8;17(1):1406
Nature communications 2026 Jan 8;17(1):1406
GPR40 Attenuates Age-Related Macular Degeneration by Suppressing Retinal Microglial NLRP3 Inflammasome Activation Via ERK Signaling.
Tan X, Kang J, Zhao H, Fang F, Xia Y, Luo C, Zou Y, Li Y
Inflammation 2026 Jan 6;49(1):29
Inflammation 2026 Jan 6;49(1):29
CGRP/TSP1 Signaling Dampens Corneal Inflammation and Fibrosis by Targeting A2M During Corneal Stromal Wound Healing.
Ge H, Zhang Y, Guo Q, Li Y, Yang L, Zang X, Xie J, Wang Y, Li Y, Qi X, Wang Y, Zhou Q, Wang X
Investigative ophthalmology & visual science 2026 Jan 5;67(1):10
Investigative ophthalmology & visual science 2026 Jan 5;67(1):10
Low-dose ciprofol attenuates motor dysfunction in PD mice by inhibiting NLRP3 inflammasome activation.
Wang Y, Li M, Li Y, Guo J, Huo X, Gao J, Wang H
Behavioural brain research 2026 Jan 5;496:115826
Behavioural brain research 2026 Jan 5;496:115826
Effects of Blue Light Exposure on Hepatic Inflammation and Gut Microbiota in Mice Consuming a High-Fat, High-Fructose Diet.
Huang WC, Lee PN, Yeh WJ, Wu WC, Shih HY, Chen YJ, Yang HY
Nutrients 2026 Jan 4;18(1)
Nutrients 2026 Jan 4;18(1)
ZM-306416 prevents ovariectomy-induced bone loss by promoting osteoblastogenesis and inhibiting osteoclastogenesis.
Li Y, Shi S, Yang D, Zhao L, Chen T, Xu K, Liang W, Chen J, Chang J
Journal of orthopaedic surgery and research 2026 Jan 31;21(1)
Journal of orthopaedic surgery and research 2026 Jan 31;21(1)
Decoding Gujin Luyan Xuming decoction: How ancient wisdom meets modern science in promoting angiogenesis to ameliorate cerebral infarction.
Cai Y, Zhang M, He Q, Lu H, Kuang Y, Huang Y, Liang W, Zhu J, Deng Y, Zhao Y, Ning W
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120652
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120652
Cornuside ameliorates LPS induced cognitive dysfunction and microglial NLRP3 inflammasome activation by enhancing Sirt1-mediated autophagy.
Lian W, Yuan X, Zhou F, Tong Z, Cheng Y, Zhang W, He J, Xu J
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120615
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120615
Dictamnine inhibited keratinocyte hyperproliferation and alleviated psoriasis-like dermatitis via blocking HIF1A-mediated ferroptotic pathway.
Wang W, Zhang J, Jiang SL, Rao ZM, Liu H, Wang L, Cai CL, Xu XC, Yu CH, Wang W
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120607
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120607
Network pharmacology approach and experimental validation of Lamei pills in treating ischemic stroke based on UHPLC-QE-MS.
Li C, Liu C, Xia Y, Liu X, Wang F, Zhuo G, Ren Q
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120578
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120578
Buyang Huanwu decoction promotes post-stroke white matter repair via TREM2-Dependent microglial phagocytosis and IGF1 secretion.
Qin X, Zhang Y, Liu J, Xiao G, Guo Y, Deng H, Hao H, Xu W, Cheng X, Zhao L, Xu S
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120520
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120520
Cldn11 deficiency aggravates osteoarthritis by inhibiting Notch signalling in a Tspan5-dependent manner.
Yu X, Li Y, Chen X, Cheng J, Yu X, Xu X, Xiao Q, Zhu X, Ke C
Journal of orthopaedic surgery and research 2026 Jan 3;21(1):2
Journal of orthopaedic surgery and research 2026 Jan 3;21(1):2
Indirect ubiquitination independent of endogenous ubiquitination machinery for targeted protein degradation.
Furuhata T, Yoshida K, Fujita R, Miyamoto J, Moriyama C, Masuda-Ozawa T, Tsuchiya H, Saeki Y, Okamoto A
Communications chemistry 2026 Jan 29;9(1):52
Communications chemistry 2026 Jan 29;9(1):52
Muscle RING finger-1 facilitates skeletal muscle regeneration via regulating myoblast proliferation and differentiation.
Yang M, Ji S, Gao H, Ge H, Han X, Zhan J, Zhang Q, Xu L, Li Y, Tang Z, Bu B
Journal of translational medicine 2026 Jan 29;24(1)
Journal of translational medicine 2026 Jan 29;24(1)
Tanshinone IIA accelerates diabetic wound healing via suppression of macrophage NLRP3 inflammasome activity.
Pan T, Zhu X, Sui Y, Zhang Z, Su Y
Biochemical and biophysical research communications 2026 Jan 25;797:153171
Biochemical and biophysical research communications 2026 Jan 25;797:153171
Hypoxic glycolysis-driven histone lactylation activates NHE7 to promote endometrial cancer progression via COX6C-mediated endoplasmic reticulum stress.
Yang S, Wu T, Cao Z, Chen Z, Ma Y, Wang T, Qian L, Huang X
Apoptosis : an international journal on programmed cell death 2026 Jan 23;31(2):55
Apoptosis : an international journal on programmed cell death 2026 Jan 23;31(2):55
Multi-omics analysis identifies TBCB as a therapeutic target in sepsis-induced liver injury.
Ma X, Peng Z, Lei K, Xu W, Lu J, Mei Z, Wen D, Li C, Liu Z
International journal of surgery (London, England) 2026 Jan 23;112(4):9535-50
International journal of surgery (London, England) 2026 Jan 23;112(4):9535-50
Thrombomodulin protects against acute vascular and multiorgan injury in sickle cell disease.
Ren G, Fraidenburg DR, Setty S, Chen J, Gonzales J, Ruiz MA, Ivy Z, Eskandari N, Minshall RD, Lash JP, Gordeuk VR, Saraf SL
JCI insight 2026 Jan 23;11(2)
JCI insight 2026 Jan 23;11(2)
SPIB suppresses protective autophagy via the IFIT2/PINK1/Parkin axis to promote anoikis in colorectal cancer.
Deng Q, Chen Y, Chen Z, Fu Z
Cancer cell international 2026 Jan 22;26(1)
Cancer cell international 2026 Jan 22;26(1)
UTY coordinates with UTX to repress NK cell development and maturation in males.
Huang P, Wang H, Guan X, Pu R, Wu Y, Huang H, Yao K, Hu D, Zhou S, Song L, Meng M, Bi Q, Wang Y, Zhong Z, Liao X, Dong H, Zhang Q, Zhang J, Sun C, Li X, Zhao J, Miao H, Li P, Xie J, Deng Y
Journal of immunology (Baltimore, Md. : 1950) 2026 Jan 21;215(1)
Journal of immunology (Baltimore, Md. : 1950) 2026 Jan 21;215(1)
Positive feedback regulation between USP8 and Hippo/YAP axis drives triple-negative breast cancer progression.
Li X, Yang P, Wang T, Su P, Zhang C, Fangyu S, Yang H, Zhu J, Tan X, Zhuang T
Cell death & disease 2026 Jan 21;17(1):98
Cell death & disease 2026 Jan 21;17(1):98
Betaine Inhibits Ferroptosis After Intracerebral Hemorrhage by Activating the Nrf2/HO-1 Pathway.
Chen J, Lu X, Liu S, Hu W, Zhou X, Wang Z
Antioxidants (Basel, Switzerland) 2026 Jan 21;15(1)
Antioxidants (Basel, Switzerland) 2026 Jan 21;15(1)
Revealing the anti-tumor mechanisms of aromatic oil from Amomum villosum through integrated network pharmacology, bioinformatics, machine learning, single-cell sequencing, and cell experiments.
Deng K, Wei Y, Yu K, Mei Y, Han S, Yan Q
Biochemical and biophysical research communications 2026 Jan 18;796:153153
Biochemical and biophysical research communications 2026 Jan 18;796:153153
Strategically isolated bacteriophages targeting ETEC K88 (F4) alleviate post-weaning diarrhea in piglets via modulation of gut microbiota and inflammatory responses.
Chen Y, Ding M, Chen X, Zou T, Liu Y, Chen J, You J
Journal of animal science and biotechnology 2026 Jan 18;17(1):11
Journal of animal science and biotechnology 2026 Jan 18;17(1):11
Comprehensive pan-cancer analysis reveals SH3GLB1 is a novel prognostic biomarker with immunomodulatory potential.
Sun X, Li R, Liu H, Zhang D, Wang S, Zhang Y, Gao W, Li D, Dong G
Biology direct 2026 Jan 17;21(1):20
Biology direct 2026 Jan 17;21(1):20
Ginseng Polysaccharides Protect Against Endoplasmic Reticulum Stress-Induced Damage via PI3K/Akt Signalling Pathway in Bovine Ovarian Granulosa Cells.
Wang H, Fang Y, Huang L, Yang X, Ma X, Lyu Y, Jing G, Ding H, Liu H, Lyu W
Cells 2026 Jan 17;15(2)
Cells 2026 Jan 17;15(2)
Liraglutide Ameliorates Injury-Related Vascular Repair by Activating Autophagy Through Modulation of the PI3K-mTOR Signaling Pathway.
Zhang Z, Wu G, Xu C, Li S, Zhang Y, Hu Y, Wu W, Ding H, Liu Y, Huang Y, Lu W, Zheng M, Zhang Y, Wu H, Hu L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Jan 15;40(1):e71357
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Jan 15;40(1):e71357
Role of gut microbiota in lead-induced neural damage in diabetic mice.
Ding WJ, Liu CQ, Tang XY, Shang ZB, Liang X, Tao T, Liu RX, Jiang QY, Qiu YF, Sun Y
World journal of diabetes 2026 Jan 15;17(1):112885
World journal of diabetes 2026 Jan 15;17(1):112885
Neutrophil extracellular traps induce hepatocyte pyroptosis via CCDC25 in sepsis-associated liver injury.
Li Z, Xiao Y, Yang L, Liang F, Xu H, Gao F
International immunopharmacology 2026 Jan 15;169:115991
International immunopharmacology 2026 Jan 15;169:115991
FDCA Attenuates Neuronal Ferroptosis and Reduces Hemorrhagic Transformation After Ischemic Stroke with High Glucose.
Fu R, Xie L, Guan X, Liang Z, Zhao Q, Huang Z, Wu Q, Pang T
Cellular and molecular neurobiology 2026 Jan 14;46(1):28
Cellular and molecular neurobiology 2026 Jan 14;46(1):28
Dunaliella salina-Loaded Diosmetin Carriers Alleviate Oxidative Stress and Inflammation in Cisplatin-Induced Acute Kidney Injury via PI3K/AKT Pathway.
Huangfu Y, Chen W, Guo D, Wang P, Li A, Yang Y, Li S, Wang Q, Wang B, Feng S
Pharmaceutics 2026 Jan 12;18(1)
Pharmaceutics 2026 Jan 12;18(1)
Investigation of BECN1-Mediated Autophagy Mechanisms Triggered by External Stimuli in Clinical Mastitis of Dairy Cows.
Cai N, Zhang B, Chen N, Yue J, Li J, Dong W, Zhang Y, Zhao X, Zhang Q
Biomolecules 2026 Jan 12;16(1)
Biomolecules 2026 Jan 12;16(1)
Huazhuo Sanjie Chubi Decoction attenuates gouty arthritis and kidney fibrosis by regulating urate transporters and JAK2/STAT3 pathway.
Zhong X, Lin S, Zhong M, Zhang Z, Chen X, Guo J, Chen P, Zheng Y, Huang M, Su Y
Journal of ethnopharmacology 2026 Jan 10;354:120457
Journal of ethnopharmacology 2026 Jan 10;354:120457
7-dehydrocholesterol promotes CCL2-secretion from porcine skeletal muscle satellite cells, enhancing the migration of preadipocytes.
Zhao Y, Yao Y, Wang X, Zhang L, Wei W, Chen J
Biochemical and biophysical research communications 2026 Jan 1;794:153070
Biochemical and biophysical research communications 2026 Jan 1;794:153070
Curzerene Ameliorates Depression-Like Behaviors and Cognitive Impairment by Modulating the Gut Microbiota and HMGB1/RAGE/TLR4 Pathway.
Huang F, Ma X, Xu X, Zhang J, Wang C, Song R, Wang X, Chen M, Qi Y
Biomolecules & therapeutics 2026 Jan 1;34(1):174-188
Biomolecules & therapeutics 2026 Jan 1;34(1):174-188
Contribution of ferroptosis and SLC7A11 to light-induced photoreceptor degeneration.
Huang X, Zhang Y, Jiang Y, Li T, Yang S, Wang Y, Yu B, Zhou M, Zhang G, Zhao X, Sun J, Sun X
Neural regeneration research 2026 Jan 1;21(1):406-416
Neural regeneration research 2026 Jan 1;21(1):406-416
Jubang Huashi Yin and its active component cynaroside alleviate excessive inflammation in COVID-19 by inhibiting IKKβ activity.
Huang W, Qiao L, Bao L, Shao J, Liu T, Zhang Z, Guo H, Qin C, Xu X, Cheng J, Shi Y, Ma H, Liu Q, Xie L
International immunopharmacology 2026 Jan 1;168(Pt 2):115914
International immunopharmacology 2026 Jan 1;168(Pt 2):115914
Lycium barbarum polysaccharide LBP3 alleviates 5-Fluorouracil-induced intestinal injury via a mechanism associated with activating Nrf2 and improving mitochondrial function.
Xie X, Cai Y, Xu R, Yang C, Li P, Zhu Y, Luo X, Zhou L, Wang Q
International immunopharmacology 2026 Jan 1;168(Pt 2):115879
International immunopharmacology 2026 Jan 1;168(Pt 2):115879
STING deficiency alleviates ischemia-reperfusion injury via JAK2/STAT3-mediated macrophage polarization and autophagy.
Zhang Y, Jing Y, Liao H, Ding K, Zhang L, Liao S, Kadier T, Chen R, Meng Q
International immunopharmacology 2026 Jan 1;168(Pt 1):115784
International immunopharmacology 2026 Jan 1;168(Pt 1):115784
Celastrol nanomedicine eye drops restore redox homeostasis and prevents keratoconus progression via PI3K/AKT/AP-1 signaling.
Liu R, Ma R, Zhang N, Geng X, Li J, Zhu L, Li Z
Redox biology 2026 Feb;89:103990
Redox biology 2026 Feb;89:103990
PHGDH-dependent serine metabolism in astrocytes: A key regulator of oxidative stress and pyroptosis in cerebral ischemia-reperfusion injury.
Zhang J, Luo Y, Xie C, Zhang M, Qin H, Zhou Y, Wu X, Hu C, Hu F, Fei X, Zhang H, Li J, Fu Y, Yuan Y, Yang S, Gao D
Redox biology 2026 Feb;89:103954
Redox biology 2026 Feb;89:103954
Atomic-level regulation of the coordination structure in single-atom Fe nanozymes for tumor catalytic therapy.
Gao X, Guo Y, Wang S, Li J, Xin H, Zhou Z, Yang F, Nie M, Song F, Wang Y, Dai C, Wen Z
Journal of colloid and interface science 2026 Feb;703(Pt 1):139085
Journal of colloid and interface science 2026 Feb;703(Pt 1):139085
Tryptophan and polyamine metabolism dysregulation serves as an early marker of high-fat diet-induced glucose intolerance.
Gao J, Zhang L, Zhan S, Peng Z, Du J, Zhang Z, Xu L, Huang S, Wang X, Guo X
Journal of lipid research 2026 Feb;67(2):100980
Journal of lipid research 2026 Feb;67(2):100980
Selective autophagic degradation of glycolytic activator PFKFB3 contributes to maintaining intestinal epithelial barrier in inflammatory bowel disease.
Pan Y, Yang F, Wang L, Yang T, Du G, Xu C, Yang H, Yu M, Xiao W
International journal of molecular medicine 2026 Feb;57(2)
International journal of molecular medicine 2026 Feb;57(2)
BACH1 is stabilized by vitamin E and attenuates the formation of hypertrophic scar through the Wnt/β-catenin pathway.
Luan W, Fan S, Jiang H, Jiang D, Yang J, He L
Burns : journal of the International Society for Burn Injuries 2026 Feb;52(1):107807
Burns : journal of the International Society for Burn Injuries 2026 Feb;52(1):107807
Shionone ameliorates pulmonary fibrosis by activating mitophagy via PINK1-Parkin pathway.
Su Y, Fu Q, Wu X, Che X, Jiang Z, Li X
Toxicology and applied pharmacology 2026 Feb;507:117693
Toxicology and applied pharmacology 2026 Feb;507:117693
Diagnostic potential of neutrophil extracellular traps in ulcerative colitis: a gene-based predictive model.
Liang H, Xu Y, Zhang X, Han Z, Zhu J
Molecular and cellular biochemistry 2026 Feb;481(2):923-945
Molecular and cellular biochemistry 2026 Feb;481(2):923-945
Long non-coding RNA STMN1P2 promotes breast cancer doxorubicin resistance by inhibiting pyroptosis through the hnRNPU-EZH2-TARF6-MALT1-caspase-1 pathway.
Jin YP, Xu BJ, Zhang XF, Wang X, Wang L, Li LY, Chen SY, Zhu P, Zhi XL, Lv L, Wang CF, Wang ZL, Sun YB, Zhou P
Acta pharmacologica Sinica 2026 Feb;47(2):419-433
Acta pharmacologica Sinica 2026 Feb;47(2):419-433
BMP1 inhibitor UK383367 improves MI-induced cardiac remodeling and fibrosis in mice via ameliorating macrophage polarization and mitochondrial dysfunction.
Guo CH, Wang QQ, Li JQ, Ji W, Chen L, Chang ML, Ma LY, Liu XL, Ni M
Acta pharmacologica Sinica 2026 Feb;47(2):315-327
Acta pharmacologica Sinica 2026 Feb;47(2):315-327
Neuroprotective Effects of Salvia Miltiorrhiza-Derived Extracellular Nanovesicles in Traumatic Brain Injury.
Chen BB, Wang Y, Li YN, Han CC, Guo JX, Meng JJ, Sun WX, Kong WH, Feng L, Rong R, Jiang P
Journal of neurotrauma 2026 Feb;43(3-4):295-316
Journal of neurotrauma 2026 Feb;43(3-4):295-316
Therapeutic Potential of Curcumin in Diabetic Cardiomyopathy: Modulation of Pyroptosis Pathways.
Wang F, Liu L, Wang J, Zhou Y, Feng X, Liu K
Cardiovascular drugs and therapy 2026 Feb;40(1):53-64
Cardiovascular drugs and therapy 2026 Feb;40(1):53-64
Glycyrrhizic acid-loaded biomimetic hybrid liposomes targeting inflammatory cascades and PD-1/PD-L1 pathway to reverse neuroinflammation-driven cognitive decline.
Wang Y, Luo F, Zhang P, Niu H, Tan Y, Zhang Y, Tang Z, Du L, Jin Y, Jin X
Materials today. Bio 2026 Feb;36:102657
Materials today. Bio 2026 Feb;36:102657
Dynamin-Related Protein 1-Dependent Disruption of Mitochondrial Homeostasis Drives Blue Light-Induced Epithelial-Mesenchymal Transition in Retinal Aging.
Li ZY, Yang D, Huang Y, Li Y, Zhao T, Xu Y
Aging cell 2026 Feb;25(2):e70416
Aging cell 2026 Feb;25(2):e70416
NMNAT1 Activates Autophagy to Delay D-Galactose-Induced Aging in Cochlear Hair Cells.
Wei Y, Yang W, Wu H, Kong M, Fan D, Zhang Y, Cheng N, Du J, Guo L, Li Y, Zhang Y, Dai Q, Cao W, Yang J, Fang Q
Aging cell 2026 Feb;25(2):e70373
Aging cell 2026 Feb;25(2):e70373
3-Deoxy-3β-syringoylamino-betulinic acid Reduces Breast Tumor Growth and Lung Colonization, With Associated Downregulation of the RAS/RAF/MEK/ERK Pathway.
Liu H, Su PW, Song H, Wang C, Shan P, Zhang H
Chemistry & biodiversity 2026 Feb;23(2):e02436
Chemistry & biodiversity 2026 Feb;23(2):e02436
Health risk assessment of emerging PFOS substitute 8:2 Cl-PFESA: evidence from mouse spermatogenesis and derivation of a safe exposure threshold.
An Z, Liu Z, Zeng X, Jiang Z, Chen Z, Zhu Y, Li L, Sun T, Zheng C, Liu X, Liu Y, Tan Z, Guo H
Environment international 2026 Feb;208:110134
Environment international 2026 Feb;208:110134
Differentiating Damp-Heat and Cold-Damp Diarrhea in Rat Models via Gut Microbiota Dysbiosis and Short-Chain Fatty Acid Profiling.
Zhang H, Song X, Mi W, Ji P, Wei Y, Hua Y
MicrobiologyOpen 2026 Feb;15(1):e70164
MicrobiologyOpen 2026 Feb;15(1):e70164
Liquiritigenin alleviates high-salt diet-induced heart damage by inhibiting TGF-β1/Smad signaling and reducing inflammation and fibrosis.
Yan W, Wang L, Zhu W, Liu X, Dong Q, Jin X, Zhang H, Dong Z
The Journal of nutritional biochemistry 2026 Feb;148:110151
The Journal of nutritional biochemistry 2026 Feb;148:110151
HMMR is a novel prognostic marker and a potential therapeutic target for colon cancer.
Fang L, Lin J, Huang D, Li J, Cui W, Deng M, Zhang Y
Cellular signalling 2026 Feb;138:112249
Cellular signalling 2026 Feb;138:112249
Brd4 BD1 Domain Antagonism of MS436 Preserves Blood-Brain Barrier Integrity via Rnf43/β-Catenin Signaling Pathway.
Li C, Zhang X, Xia J, Liu S, Du Y, Li S, Zhang S, Zhang Y, Ji F, Jiao J, Zhang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(7):e15584
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(7):e15584
Genome-Wide CRISPR Screen Reveals PIK3CA Inhibition Enhances Lipid Nanoparticle-Mediated siRNA Delivery.
Wang W, Chen K, Wang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(11):e17617
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(11):e17617
CRISPRi Screening Identifies Essential E. coli Virulence Factors for Placental Barrier Breach in a Maternal-Fetal Infection Model.
Cai X, Liang X, Zou P, Xiao R, Wang Y
International journal of molecular sciences 2026 Feb 9;27(4)
International journal of molecular sciences 2026 Feb 9;27(4)
Unraveling the Cold Property of Gardeniae Fructus: Material Basis and Biological Mechanisms.
Yang C, Wu S, Huang X, Wu Z, Fan Y, Liu X, Zhong R, Rao Y, Liu J, Fu X
International journal of molecular sciences 2026 Feb 9;27(4)
International journal of molecular sciences 2026 Feb 9;27(4)
Grass carp reovirus VP35 hijacks DHX15 into phase-separated inclusion bodies to evade host antiviral immunity.
Zhang C, Lv Z, Zeng W, Zhang YA, Tu J
Cell communication and signaling : CCS 2026 Feb 9;24(1)
Cell communication and signaling : CCS 2026 Feb 9;24(1)
SERPINE1-Driven MAPK Activation Enhances Cuproptosis Resistance and Angiogenic Potential in Colorectal Cancer.
Gao P, Li H, Luo J, Zhang C, Wei J, Li X, Ma H
Digestive diseases and sciences 2026 Feb 9;
Digestive diseases and sciences 2026 Feb 9;
Citrate-coated Prussian blue nanozyme hitchhikes neutrophils to ameliorate calcium oxalate crystal-induced kidney injury via inhibiting pyroptosis and NETosis.
Ba X, Yang X, He Y, Ye T, Zeng X, Zhong Z, Guo X, Tang K
Journal of nanobiotechnology 2026 Feb 7;24(1)
Journal of nanobiotechnology 2026 Feb 7;24(1)
Ginsenoside Rg5 Targets PRDX1 to Disrupt Redox Homeostasis and Induce Mitochondria-Dependent Apoptosis in Human Hepatocellular Carcinoma HepG2 Cells.
Ye HL, Wang YN, Li GA, Jin XH, Wu GT, Li Y, Jin YH
Molecules (Basel, Switzerland) 2026 Feb 5;31(3)
Molecules (Basel, Switzerland) 2026 Feb 5;31(3)
Chicory Extract Alleviates Anthracycline-Induced Cardiotoxicity by Inhibiting Mitochondrial Damage via the UCP2/NLRP3 Pathway.
Rao Y, Wang Y, Liu Y, Huang J, Ding X, Lin Z, Zhang B, Zhang X
International journal of molecular sciences 2026 Feb 5;27(3)
International journal of molecular sciences 2026 Feb 5;27(3)
Integrated metabolomics and 16S rRNA sequencing reveal the mechanism of total flavones of Abelmoschus manihot (L.) Medic against liver fibrosis.
Li D, Ge H, Zhang Y, Song S, Xing L, Tang EH, Wang F
Scientific reports 2026 Feb 5;16(1)
Scientific reports 2026 Feb 5;16(1)
DCC-2036 induces repolarization of TAMs to M1 type and enhances CD8(+) T cell immunity in TNBC.
Liang Y, Zeng Q, Xiao M, Li P, He R, Chen Z, Liu J, Cao J, Li J, Yin L, Zhong J, Chen X, Feng J, He J, Chen X, Zu X, Shen Y
Molecular therapy : the journal of the American Society of Gene Therapy 2026 Feb 4;34(2):985-1008
Molecular therapy : the journal of the American Society of Gene Therapy 2026 Feb 4;34(2):985-1008
Macrophage-Mimicking Biomimetic Microbubbles for Early Ultrasound Molecular Imaging of Acute Rejection in Heart Transplantation.
Wang C, Li G, Chen J, Liu C, Liu Y, Ai X, Yang Y, Leng X, Wang Z, Jiang S
ACS applied materials & interfaces 2026 Feb 4;18(4):6639-6655
ACS applied materials & interfaces 2026 Feb 4;18(4):6639-6655
Targeting TFAM K76 acetylation attenuates mitochondrial dysfunction and kidney injury in diabetic kidney disease.
Fu T, Sun S, Wang Z, Zhao F, Zhen J, Ji X, Xue F, Mu Q, Wang Y, Liu Y, Wan Q
Cardiovascular diabetology 2026 Feb 3;25(1)
Cardiovascular diabetology 2026 Feb 3;25(1)
ROS-Scavenging Bamboo-Derived Carbon Dot-Methotrexate Nanocomposite Ameliorates Rheumatoid Arthritis through Dual Therapeutic Mechanisms.
Hu XR, Wang F, Zhao BF, Xu F, Wang Y
ACS omega 2026 Feb 3;11(4):5853-5864
ACS omega 2026 Feb 3;11(4):5853-5864
A TRIM21-UCHL3-ITCH-SIPA1 axis promotes colorectal cancer growth and metastasis.
Lou S, Wang H, Mo G, Li H, Xie H, Huang Y, Li H, Ma K, Zhang X, Yan M, Zhang J, Pi Y, Han P
Cancer letters 2026 Feb 28;639:218221
Cancer letters 2026 Feb 28;639:218221
Integrative analysis of single-cell RNA sequencing, bulk RNA sequencing, and proteomic data identified NOTCH3 as a hub gene contributing to human intervertebral disc fibrosis.
Ding Q, Chen X, Zheng Q, Dou Q, Zuo C, Wang Q, Shen C
Scientific reports 2026 Feb 26;16(1)
Scientific reports 2026 Feb 26;16(1)
NEAT1 drives SARS-CoV-2 N protein-induced inflammation, metabolic reprogramming, and mitochondria-ER stress crosstalk.
Qing C, Chen H, Huang S, Zhang J, Zhou C, Zhang S, Luo K, Wang C, Hu Z, Yang Y, Zhou J, Zeng Z
Scientific reports 2026 Feb 25;16(1)
Scientific reports 2026 Feb 25;16(1)
Triptonide Suppresses AML via PI3K/AKT Signaling: A Network Pharmacology Approach Validated by Molecular Docking and Experimental Studies.
Song L, Meng J, Li H, Fu W, Hong K, Shen S, Zhang Z, Ding S, Li S, Zhang Z, Bei W, Huo H, Tan Y, Sui F, Liu L
Current issues in molecular biology 2026 Feb 24;48(3)
Current issues in molecular biology 2026 Feb 24;48(3)
FGF4 activates FGFR1 - PI3K/AKT signaling to enhance Clec10a-mediated intracellular myelin debris processing and promote spinal cord repair.
Lu W, Jiang M, Zhuang J, Song J, Zhou C, Zhou Y, Zhu Z, Wu A, Sheng S, Zhu S, Wang Z
Journal of neuroinflammation 2026 Feb 23;23(1)
Journal of neuroinflammation 2026 Feb 23;23(1)
Psoralen Promotes Direct Chemical Reprogramming of Mouse Embryonic Fibroblasts into Osteoblast-like Cells.
Li W, Liu H, Wan X, Cheng D, Zhu R, Zhang Z
Pharmaceutics 2026 Feb 23;18(2)
Pharmaceutics 2026 Feb 23;18(2)
Integration of Bulk and Single-Cell Transcriptomics Reveals Prognostic and Immunological Roles of MTHFD2 in Clear Cell Renal Cell Carcinoma.
Zhou Y, Zheng X, Ye P, Yang H
International journal of molecular sciences 2026 Feb 20;27(4)
International journal of molecular sciences 2026 Feb 20;27(4)
Monocyte-macrophage SAMHD1 alleviates EAMG by modulating the cGAS-STING pathway.
Que W, Fan R, Lu D, Liu L, Dong J, Ke P, Jing S, Gan Y, Xiao F
Journal of neuroinflammation 2026 Feb 19;23(1)
Journal of neuroinflammation 2026 Feb 19;23(1)
Foodborne PET Microplastic Contamination Compromises Intestinal Barrier through a Mitochondrial-AMPK-DNA Damage Pathway.
Zhang C, Yan Y, Li X, An J, Li W, Shao J, Guo Z
Journal of agricultural and food chemistry 2026 Feb 18;74(6):5718-5730
Journal of agricultural and food chemistry 2026 Feb 18;74(6):5718-5730
Supramolecular delivery of senolytics enables targeted anti-senescence therapy and accelerated fracture healing.
Fan Y, Wang ZH, Zhang X, Dong Y, Liu X, Luo G, Yang H, Li H, Wang Z, Tang Q, Jin X, Guo DS, Sun T
Journal of nanobiotechnology 2026 Feb 18;24(1)
Journal of nanobiotechnology 2026 Feb 18;24(1)
Fascin-1 Limits Secondary Damage by Preventing Oxidative‑Stress‑Induced Microglial Death After Spinal Cord Injury.
Zhan F, Xu D, Shi T, Niu H, Wang S, Feng E, Cao Y
Neurochemical research 2026 Feb 17;51(2):75
Neurochemical research 2026 Feb 17;51(2):75
LL37-induced mitochondrial stress activates the mtDNA/cGAS/STING pathway to promote mast cell-mediated rosacea inflammation.
Sun R, Fan H, Ma Q, Li X, Liu J, Xu C, Liu C, Zhang D, Ma W
Free radical biology & medicine 2026 Feb 16;244:422-434
Free radical biology & medicine 2026 Feb 16;244:422-434
Mitochondrial uncoupling sensitizes gastric cancer cells to elesclomol-induced cuproptosis via FDX1/DLAT upregulation.
Lu Y, Li Y, Sun X, Li X, Zhao S, Fang Y, Qiu W, Luo C, Qi W
Free radical biology & medicine 2026 Feb 16;244:284-295
Free radical biology & medicine 2026 Feb 16;244:284-295
LBPs NPs suppress breast cancer progression by inhibiting YAP1 expression to induce ferroptosis and alter energy metabolism.
Zhao F, Yang S, He T, Yang L, Mo T, Kang J, Cao H, Sun X, Yu Y
Scientific reports 2026 Feb 16;16(1)
Scientific reports 2026 Feb 16;16(1)
Asporin regulates glycolysis and stemness of gastric cancer cells.
Xu G, Cai Z, Zhuang Y, Wang H, Lin Q, Guo T, Tao H
Journal of molecular histology 2026 Feb 13;57(2):74
Journal of molecular histology 2026 Feb 13;57(2):74
Integrated bioinformatics and experimental validation identify CCDC78 as a prognostic biomarker in colon adenocarcinoma.
Mo Q, Du M, Zheng J, Yu J, Ma Z, Zhuang S, Jiang M
Scientific reports 2026 Feb 12;16(1)
Scientific reports 2026 Feb 12;16(1)
ZIKV envelope protein is a strong blocker of early directional differentiation in the neural lineage.
Ma ZH, Wang Y, Hassaan NA, Chu XN, Wang PH, Wu C, Xing L
Communications biology 2026 Feb 10;9(1)
Communications biology 2026 Feb 10;9(1)
Circadian disruption induces cognitive impairment through tryptophan-5-HT metabolic pathway dysregulation.
Liao J, Wang Y, Li J, Li P, Liu Y, Wu J, Zhao M, Huang H, Liu P, Chen Y, Xu Y, Jiang Y
Sleep 2026 Feb 10;49(2)
Sleep 2026 Feb 10;49(2)
Zhichuanling oral liquid attenuates airway inflammation in asthma by targeting the STIM1/CHOP/JNK axis.
Chen H, Xing S, Wu J, Li Y, Yang X, Wang Z, Zhu J, Lv S, Xu S, Zhu Y, Sun L
Journal of ethnopharmacology 2026 Feb 10;356:120859
Journal of ethnopharmacology 2026 Feb 10;356:120859
Yinhuo Tang alleviates ionizing radiation injury via modulating PI3K-Akt signaling and metabolomics in mice.
Li Y, Lu D, Zhou L, Zhang Y, Yang C, Liu S, Zhang X, Zhao M, Yang Y
Journal of ethnopharmacology 2026 Feb 10;356:120843
Journal of ethnopharmacology 2026 Feb 10;356:120843
Qingyu Yangjing formula ameliorates cyclophosphamide-induced oligoasthenospermia by regulating the hypothalamic-pituitary-gonadal axis and inhibiting testicular oxidative stress and apoptosis in rats.
Li X, Qin L, Sun Y, Zou K, Zhao C, Xiao M, Yan S, Zhang X, Shen Y, Tian L, Liu S
Journal of ethnopharmacology 2026 Feb 10;356:120842
Journal of ethnopharmacology 2026 Feb 10;356:120842
Prebiotic augmented nanozyme-armored probiotics reprogramme the gut microenvironment for synchronous treatment of colitis and sepsis via antioxidant defense.
Sun R, Wang Y, Fan J, Wang Z, Yue T, Yuan Y
Journal of advanced research 2026 Feb 10;
Journal of advanced research 2026 Feb 10;
Trimethylamine-N-oxide disrupts spermatogenesis by inducing mitochondrial oxidative stress injury through Hippo signaling.
Wang S, Ma G, Qi C, Cheng S, Lai H, Zhou L, Wu G, Chen Z, Mao X, Jing T, He Y, Zhou H
Free radical biology & medicine 2026 Feb 1;243:452-465
Free radical biology & medicine 2026 Feb 1;243:452-465
An intrabody targeting PHD2 protects mice against acetaminophen-induced liver injury by attenuating ferroptosis.
Ren Z, Wang Y, Cheng C, Zhang Y, Liu Y, Wei Y, Liu Z, Zhang J, Shi Z, Yu J, Hu W, Ye J, Wang J, Qiu S, Li G
Free radical biology & medicine 2026 Feb 1;243:260-275
Free radical biology & medicine 2026 Feb 1;243:260-275
Charge-flip nanoparticles loaded with TAK1 inhibitors inhibit retinal neovascularization.
Teng X, Yuan Z, Li M, Sun L, Xiong X, Sha X, Liu L, Yu G, Tu L, Chan L, Zhong J
Journal of nanobiotechnology 2026 Feb 1;24(1)
Journal of nanobiotechnology 2026 Feb 1;24(1)
Bromodomain-containing protein 4 knockdown promotes neuronal ferroptosis in a mouse model of subarachnoid hemorrhage.
Lu P, Zhang F, Yang L, He Y, Kong X, Guo K, Xie Y, Xie H, Xie B, Jiang Y, Peng J
Neural regeneration research 2026 Feb 1;21(2):715-729
Neural regeneration research 2026 Feb 1;21(2):715-729
Overconsumption of fructose aggravates acute GVHD by inducing gut dysbiosis and promoting macrophage-mediated inflammatory response.
Wu K, Yu H, Cao K, Dai B, Yuan Y, Qian X, Zhong H, Qu Y, Jiang H, Chen T
Gut microbes 2026 Dec 31;18(1):2642459
Gut microbes 2026 Dec 31;18(1):2642459
Gut-confined fullerene reprograms lactate metabolism to Rescue hypoxia-induced exercise intolerance.
Chen S, Pan Y, Liu M, Liu C, Xu Y, Ma J, Li J, Wang X, Yang L, Wang Y, Li B, Wang Z, Zhang Y, Shen H, Wulan Q, Li J, Wang C, Bai C
Biomaterials 2026 Aug;331:124075
Biomaterials 2026 Aug;331:124075
Organelle stress in pyometra: Molecular evidence of endoplasmic reticulum stress and mitochondrial dysfunction.
Zhao W, Deng X, Tang J, Li S, Hu B
Theriogenology 2026 Aug;260:117919
Theriogenology 2026 Aug;260:117919
KLK8 promotes cartilage degradation and pyroptosis in osteoarthritis by activating the NF-κB and NLRP3 inflammasome pathways.
Xu L, Jiang Z, Li H
Tissue & cell 2026 Aug;101:103427
Tissue & cell 2026 Aug;101:103427
P2Y2 receptor as a favorable predictor of gastric cancer.
Wu YQ, Wang WL
Tissue & cell 2026 Apr;99:103278
Tissue & cell 2026 Apr;99:103278
Tussilagone attenuated cigarette smoke-induced chronic obstructive pulmonary disease through regulating Nrf2 and NF-κB/NLRP3 inflammasome via directly targeting cysteine 434 of KEAP1.
Xu LT, Han QT, Xu ZP, Wang XN, Zhang H, Shen T
Journal of advanced research 2026 Apr;82:1149-1162
Journal of advanced research 2026 Apr;82:1149-1162
Inhibition of GPR75 Alleviates Lipid Metabolism by Activating the AMPK-SIRT1 Signaling Pathway In Vitro and In Vivo.
Wang J, Sun G, Li S, He X, Zou R, Li K, Wu B
Molecular biotechnology 2026 Apr;68(4):1965-1978
Molecular biotechnology 2026 Apr;68(4):1965-1978
Identification of a Novel Mitochondrial-Related Gene Signature for BMSCs in Osteoporosis Combining Single-Cell and Bulk Transcriptome Data.
Jiang J, Li D, Cui D, Wan Y, Zhou P, Cui X, Yu H
Biochemical genetics 2026 Apr;64(2):1525-1548
Biochemical genetics 2026 Apr;64(2):1525-1548
Serine Promotes Inflammatory Macrophage Polarisation in Periodontitis via NAD(+) Signalling.
Fang L, Wang J, Xiang J, Xu L, Zhao S, He Y, Liu X, Ye H, Zhang H, Zhang H, Ji P, Chen C, Zhai Q, Cannon R
Journal of clinical periodontology 2026 Apr;53(4):596-615
Journal of clinical periodontology 2026 Apr;53(4):596-615
Ginkgetin inhibits non-small cell lung cancer via the HSP90-AKT signaling pathway.
Li R, Gao H, Wang M, Zhang Y
Naunyn-Schmiedeberg's archives of pharmacology 2026 Apr;399(7):10815-10830
Naunyn-Schmiedeberg's archives of pharmacology 2026 Apr;399(7):10815-10830
An alkaline nanosized platelet vesicle-based hydrogel for the treatment of osteoporotic bone defects.
Yang K, Yang Y, Xia C, Chen Y, Dai Z, Wang Z, Hu L, Li Y, Wang Y, Wang Y, Li W, Wang Q, Li N, Jiang S, Zu S, Hao F, Shen Q, Fan S, Chen P, Shangguan L, Ning L
Materials today. Bio 2026 Apr;37:103000
Materials today. Bio 2026 Apr;37:103000
Transdermal siRNA delivery via biomineralized nanoparticle-incorporated microneedles modulates cuproptosis-ferroptosis interaction for psoriasis therapy.
Hao L, Yu P, Yan R, Li K, Luo Z, Xiang S, Wang Y, Fang C, Wang G, Ma S, Peng C, Hu S, Liu P
Materials today. Bio 2026 Apr;37:102991
Materials today. Bio 2026 Apr;37:102991
Dual-responsive PDA-HP hydrogel enables mitochondria-targeted mild photothermal therapy for spinal cord repair.
Li Y, Hu J, Ran B, Zhong H, Zhong N, Zhong Y, Fu X, Liu X, Wu G, Zhong Q, Li J
Materials today. Bio 2026 Apr;37:102783
Materials today. Bio 2026 Apr;37:102783
Panax notoginseng saponins protect the blood-brain barrier against oxidative stress by activating the Akap12-PI3K/AKT-AQP1 signaling axis.
Fan L, Qu S, Miao C, Wu D, Rao Y, Xu W, He Y, Ding R, Song G
International journal of biological macromolecules 2026 Apr;353:151045
International journal of biological macromolecules 2026 Apr;353:151045
Laminarin attenuates neuroinflammation in MPTP-induced Parkinson's disease mouse model via inhibiting dectin-1/Syk/NF-κB signaling.
Zhao RY, Zhang M, Wang XW, Xue F, Zheng YY, Chen WF
Inflammopharmacology 2026 Apr;34(4):2723-2733
Inflammopharmacology 2026 Apr;34(4):2723-2733
Hydrogen-releasing electroactive nerve guidance conduits promote peripheral nerve regeneration by remodeling the microenvironment.
Li Z, Su J, Dong X, Liang X, Huo Y, Yang J, Yan L, Yu A, Dai H
Biomaterials 2026 Apr;327:123752
Biomaterials 2026 Apr;327:123752
The Dual Role of Gastrodin in Spinal Cord Injury: Microglial Phenotype Switching and Neuronal Survival via PI3K/AKT Activation.
Feng J, Gao S, Hu Y, Sheng W
CNS neuroscience & therapeutics 2026 Apr;32(4):e70811
CNS neuroscience & therapeutics 2026 Apr;32(4):e70811
PUM2 knockdown regulates the expression and alternative splicing of genes associated with myocardial fibrosis in H9C2 cells.
Zhang Z, Zhou H, Adili D, Zhu W, Liu Y, Zhou W, Wang Z, Li J
Experimental and therapeutic medicine 2026 Apr;31(4):94
Experimental and therapeutic medicine 2026 Apr;31(4):94
Senescence-Driven Remodeling Defines an Aggressive and Immunomodulatory Subtype of Endometriosis.
Liu J, Han W, Tang J, Wan H, Wang H, Peng J, Ma W, Hu M, Hong L
Aging cell 2026 Apr;25(4):e70463
Aging cell 2026 Apr;25(4):e70463
Tartrate-Resistant Acid Phosphatase 5 (TRAP/ACP5) aggravates atherosclerosis by regulating macrophage polarization and promoting ferroptosis.
Ma X, Li Z, Liu H, Wang M, Gao F, Xiao Z, Qi M, Liu Z, Li Z, Huang J, Jiang Z, Feng Q, Wei D, Liu Z, Wang Z, Xiao S
Free radical biology & medicine 2026 Apr;247:486-501
Free radical biology & medicine 2026 Apr;247:486-501
Therapeutic potential of Cistanche against Parkinson's disease via regulating circulating inflammation: Insights from Mendelian randomization, molecular docking, and in vivo studies.
Liu H, Chen Y, Li C, Zhang Q, Lin X, Lin Y, Xu Q
Experimental gerontology 2026 Apr;216:113071
Experimental gerontology 2026 Apr;216:113071
The regulatory role of circGDI2 in hepatocellular carcinoma proliferation and glycolysis with the involvement of m6A modification.
Chen S, Xia H, Chen S
Non-coding RNA research 2026 Apr;17:21-31
Non-coding RNA research 2026 Apr;17:21-31
Neuroprotective effects of DPP-4 inhibitors sitagliptin and vildagliptin in Parkinson's disease via autophagy modulation.
Yizibula M, Subuhati Y, Abudourousuli A, Tuerxun X, Chan F, Zhang H, Wumaier A, Turghun C, Aimaiti M
3 Biotech 2026 Apr;16(4):146
3 Biotech 2026 Apr;16(4):146
Celastrol disrupts the inflammatory feedback loop driven by Tenascin-C⁺ fibroblast subtype in psoriasis: Insights from single-cell RNA sequencing and experimental validation.
Ma Y, Zhang X, Chen X, Zhang D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157988
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157988
Geum japonicum Thunb. var. Chinese-P.decorata H.Andres herbal pair ameliorates CIRI-induced neuronal injury by facilitating mitochondrial transfer via the CD38/Miro1 signaling pathway.
Sun F, She R, Yang T, Chen B, Liao Z, Liao J, Mei Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157928
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157928
Diosmetin alleviates hyperuricemic nephropathy by activating the BNIP3/Nrf2/GPX4 pathway to inhibit ferroptosis of renal tubular epithelial cells induced by monosodium urate crystals.
Hu C, Dong C, Yang H, Yu Z, Li Y, Qiu Y, Mei Z, Xu L
The Journal of nutritional biochemistry 2026 Apr;150:110241
The Journal of nutritional biochemistry 2026 Apr;150:110241
Diabetes Mellitus Facilitates Gallstone Formation Through CXCR2-NETs-Mediated Liver-Bile Barrier Damage.
Shi C, Feng S, Liu T, Meng Z, Zheng Y, Huang Z, Wang T, Zhang B, Xue D, Ma B, Meng X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(24):e19500
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(24):e19500
Structure-Based Discovery of Novel, Highly Potent VEGFR2 Inhibitors with a Naphthalene Scaffold against a Broad Range of Solid Tumors.
Yang T, Wei T, Sun S, Xi B, Wei P, Jia C, Qi Z, Feng F, Wei M, Wang Y, Cai X, Zhao Z, Li B, Qiao M, Zou Y, Mu Z, Lei X, Zhang Z, Lei G, Lv K, Zheng Z, Li P, Li S
Journal of medicinal chemistry 2026 Apr 9;69(7):8340-8363
Journal of medicinal chemistry 2026 Apr 9;69(7):8340-8363
Discovery, Optimization, and Biological Evaluation of 2-Cyano-2-(9H-xanthen-9-ylidene)acetamide Derivatives as ZNF207 Inhibitors for Anti-Glioma Therapy.
Gao M, Wang J, Wang Y, Li J, Feng J, Gu C, Wang Z, Gong X, Zhou W, Chen S, Xia X, Tang X, Yang Y, Zhang D, Ding Y, Zhang M
Journal of medicinal chemistry 2026 Apr 9;69(7):7594-7641
Journal of medicinal chemistry 2026 Apr 9;69(7):7594-7641
Integrated multi-omics and experimental validation for identifying novel biomarkers of acute myocardial infarction.
Qu S, Nie Q, Li J, Zhang B, Chen Z, Zhou L
Naunyn-Schmiedeberg's archives of pharmacology 2026 Apr 8;
Naunyn-Schmiedeberg's archives of pharmacology 2026 Apr 8;
Comprehensive pan-cancer analysis of AARS1, a newly identified lactyltransferase in human cancers.
Fu T, Ni K, Wang Z, Sun S, Liu Y, Wan Q
Cancer cell international 2026 Apr 8;
Cancer cell international 2026 Apr 8;
Pan-Cancer Analysis and Functional Characterization Identify SLC15A4 as a Novel Prognostic Biomarker and Therapeutic Target.
Lyu X, Lin Z, Lin Y, Zhu S, Wang P, Zhu H, Xu H, Liu P
Asia-Pacific journal of clinical oncology 2026 Apr 6;
Asia-Pacific journal of clinical oncology 2026 Apr 6;
Hyperglycemia impairs cognitive function by inducing mitochondrial damage through lactylation of LRPPRC at K223.
Xu J, Hao Y, Cao J, Yang X, Gao Y, Sun X, Nie R, Zhong Q, Zhong Y, Zhong J, Zheng T
EMBO molecular medicine 2026 Apr 6;
EMBO molecular medicine 2026 Apr 6;
AnnoNet-TCMs: An annotation network-driven discovery of novel active compounds and mechanisms in traditional Chinese medicine.
Yan X, Guo Z, Zhou F, Cui Y, Zhang Z, Jing Z, Wang L, Fan Z, Lu J, Xing X, Yang H
Journal of advanced research 2026 Apr 5;
Journal of advanced research 2026 Apr 5;
Gordonibacter-associated regulatory T cell dysfunction and S100A11-mediated neural impairment in Hirschsprung's disease: a microbiota-immune-neural axis.
Yao T, Fan M, Hao Z, Jiang Z, Li X, Wang S, Xu Z
Cell & bioscience 2026 Apr 3;16(1)
Cell & bioscience 2026 Apr 3;16(1)
YWHAZ downregulated innate immune responses to RNA viruses by inhibiting the IRF3 signaling pathway.
Li S, Han J, Wang H, Hou J, Wang L, Hou Z, Zhang Y, Dou X, Xie J, Li H, Li X, Feng R
mSphere 2026 Apr 28;11(4):e0003826
mSphere 2026 Apr 28;11(4):e0003826
Berberine Ameliorates Atherosclerosis by Promoting Mitochondrial Biogenesis via SIRT1/PGC-1α Signaling Pathway.
Wang SY, Zheng JM, Han XY, Jin BY, Hua CJ, Chen YS, Wang TT, Wang YH
Chinese journal of integrative medicine 2026 Apr 27;
Chinese journal of integrative medicine 2026 Apr 27;
Neudesin modulates IGF1 and insulin signaling pathways by regulating the surface expression of IGF1R through a conserved WPE motif.
Nakayama Y, Nonaka M, Masuda Y, Matsumoto H, Higashi K, Pak Y, Komoda S, Tagawa A, Shimizu R, Mikami T, Nadanaka S, Yamasaki T, Sano K, Mukai T, Kitagawa H, Konishi M
The FEBS journal 2026 Apr 25;
The FEBS journal 2026 Apr 25;
Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems.
Yao T, Liu H, Yao Y, Deng W, Sun J, Kang Z, Ali A, Shan C, Yuan Z, Deng F, Wang H, Ning YJ
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 24;:e11575
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 24;:e11575
Ameliorative Effect of Luteolin on H2O2-Induced Mitophagy and Apoptosis in Cardiomyocytes Through Modulation of the AMPK/mTOR Pathway.
Yang Z, Liu X, Liu D, Ma K, Zhao M, Wang Y
Frontiers in bioscience (Landmark edition) 2026 Apr 20;31(4):50047
Frontiers in bioscience (Landmark edition) 2026 Apr 20;31(4):50047
Triggering Receptor Expressed on Myeloid Cells-2 Regulates Innate Lymphoid Cell Levels in Bleomycin-Induced Pulmonary Fibrosis.
Shen HC, Chen NJ, Sun CY, Yu WK, Su VY, Yang WL, Chen WC, Yang KY
The Kaohsiung journal of medical sciences 2026 Apr 2;:e70209
The Kaohsiung journal of medical sciences 2026 Apr 2;:e70209
Formation of the pre-metastatic niche by COL9A1 + cancer-associated fibroblasts via SDC4 engagement promotes multi-organ metastasis in gastric cancer.
Dong X, Yang Z, Zhao Z, Liu J, Zhang M
Journal of gastroenterology 2026 Apr 18;
Journal of gastroenterology 2026 Apr 18;
RBM11 drives malignant progression of bladder cancer by regulating GNPDA1-PKM2 axis.
Tong H, Li T, Zhu J, Dou Q, Yu Q, Sun Y, He W
iScience 2026 Apr 17;29(4):115402
iScience 2026 Apr 17;29(4):115402
TRIM36 and CAMK2N2 regulate ferroptosis and antigen presentation in small cell lung cancer.
Cai Y, Zhu S, Wang H, Huang F, Yin Z, Nie J
iScience 2026 Apr 17;29(4):115310
iScience 2026 Apr 17;29(4):115310
Alpha-ketoglutarate alleviates Cadmium-induced ferroptosis in association with enhanced mitochondrial function in testes.
Wang X, Dong W, Zhao J, Chen N, Zheng T, Liu Y, Li Q, Ye H, Li H, Xie L
Reproductive toxicology (Elmsford, N.Y.) 2026 Apr 16;143:109249
Reproductive toxicology (Elmsford, N.Y.) 2026 Apr 16;143:109249
BMSC-derived exosomal ANTXR1 inhibits erythroid differentiation by suppressing the TLR4/MyD88/NF-κB signaling pathway.
Chen D, Lin L, Wu Y, Huang K, Zhang H, Chen Q
Scientific reports 2026 Apr 16;
Scientific reports 2026 Apr 16;
Pellino1 Exacerbates Diabetic Kidney Disease Through NLRP3 Inflammasome Driven Pyroptosis in Renal Tubular Epithelial Cells.
Zhou X, Zhang R, Guo Z, Yang Y, Yan R
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Apr 15;40(7):e71721
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Apr 15;40(7):e71721
Uridine metabolism promotes lung adenocarcinoma progression by activating FBL transcription via YBX1.
Wang X, Chen L, Li Y, Chen L, Hao C, Yan Q, Yu S, Zhang C, Li R, Xu B, Yao Y, Song Q
Journal of translational medicine 2026 Apr 15;24(1)
Journal of translational medicine 2026 Apr 15;24(1)
Ginsenoside Rg3 synergizes with near-infrared photothermal therapy to suppress prostate cancer progression by inhibiting RAS signaling and enhancing ARL11-mediated macrophage reprogramming.
Zhang H, Chang Y, Fu Q, Jin T, Zhang S, Zhang M
International immunopharmacology 2026 Apr 15;175:116417
International immunopharmacology 2026 Apr 15;175:116417
Quercetin alleviates imatinib-induced premature ovarian insufficiency by regulating mitophagy via the ROS/JNK/c-JUN pathway.
Li QH, Ji M, Weng SQ, Li X, Xiao Q, Zhou Y, Luo T, Liu ZX
International immunopharmacology 2026 Apr 15;175:116405
International immunopharmacology 2026 Apr 15;175:116405
Persistent testicular glycogenolysis and active lipid metabolism during torpor in hibernating Siberian chipmunks.
Wang Z, Li LF, Yan YJ, Yuan MY, Zhao XY, Jiang LN, Yi XF
Journal of thermal biology 2026 Apr 15;139:104462
Journal of thermal biology 2026 Apr 15;139:104462
Methylation of tenascin XB mediated by methyltransferase-like 3 can effectively suppress neural injury and cellular apoptosis induced by ischemic stroke.
Ding L, Feng X, Gao F
The International journal of neuroscience 2026 Apr 15;:1-13
The International journal of neuroscience 2026 Apr 15;:1-13
Mosaic Inverted Hemagglutinin Extracellular Vesicle Vaccines Elicit Protective Systemic and Mucosal Immunity against Heterosubtypic Influenza Infection.
Zhu W, Wei L, Dong C, Kim JK, Bruhn M, Ma Y, Ferrante A, Arsana A, Omotara P, Kang SM, Wang BZ
ACS nano 2026 Apr 14;20(14):10858-10871
ACS nano 2026 Apr 14;20(14):10858-10871
NT5DC2 inhibits ferroptosis by stabilizing ACSL3 in bladder cancer.
Niu S, Yang P, Yao Y, Tang X, Yang J, Zhang F, Chen K, Jiang C, Zhou Y, Bai W, Li L, Zhou Y, Lv XB
Cell death discovery 2026 Apr 14;12(1)
Cell death discovery 2026 Apr 14;12(1)
MELK is Required for G2/M Phase Progression in Cortical Progenitors: Insights from Rare ASD-Associated Variants.
Zhao L, Li X, Yang K, Jiang M, Chen Z, Shao Y, Lu T, Zhang D, Wang L, Li J
Cellular and molecular neurobiology 2026 Apr 13;46(1)
Cellular and molecular neurobiology 2026 Apr 13;46(1)
Heme oxygenase-1-enriched tolerogenic dendritic cell-derived exosomes attenuate lupus nephritis by restoring immune balance and iron homeostasis.
Xing Z, Yang J, Zhang H, Xie Y, Yang Q, Wu M, Wang W, Gao S, Hua C
Free radical biology & medicine 2026 Apr 10;251:60-74
Free radical biology & medicine 2026 Apr 10;251:60-74
PIM1 Inhibition Alleviates Aspergillus fumigatus Keratitis by Regulating DDX41-Mediated STING Signaling Pathway.
Han F, Wang L, Wu J, Ma H, Luo X, Li J
Investigative ophthalmology & visual science 2026 Apr 1;67(4):2
Investigative ophthalmology & visual science 2026 Apr 1;67(4):2
An indoloquinolinone 3a alleviates lipopolysaccharide-induced acute lung injury by modulating the NF-κB and AMPK/Nrf2 signaling pathways.
Tian W, Liu Z, Liu J, Kong L, Qin H, Zhu GY, Zhang W, Jin J, Wang X, Jiang ZH, Bai LP
International immunopharmacology 2026 Apr 1;174:116398
International immunopharmacology 2026 Apr 1;174:116398
Targeting HSPB1 inhibits tumor growth and abrogates Treg-mediated tumor immunosuppression.
Hu Q, Lu Y, Zhong X, Huang P, Zheng L, Jiang BH, Li W, Zheng SG
International immunopharmacology 2026 Apr 1;174:116333
International immunopharmacology 2026 Apr 1;174:116333
Di-(2-ethylhexyl) phthalate induces endometriosis by modulating IGF-1 m6A methylation via the intestinal Odoribacter-butyric acid axis in female rats.
Yang H, Sha Y, Zhang C, Li X, Xu Y, Liu T
Current research in microbial sciences 2025;9:100474
Current research in microbial sciences 2025;9:100474
Na(+)/K(+)-ATPase Modulates Purinergic P2X3 Receptor Function to Drive Bone Cancer Pain.
Huang S, Peng B, Dong W, He J, Chen H, Bian JS
Research (Washington, D.C.) 2025;8:0932
Research (Washington, D.C.) 2025;8:0932
Silencing of MiR-329-3p Protects against Myocardial Ischemia-Reperfusion Injury by Regulating the Wnt/β-catenin Pathway via Nemo-Like Kinase.
Wang L, Li X, Wang M, Liu Y
International heart journal 2025;66(6):986-994
International heart journal 2025;66(6):986-994
Carrier-Free Peptide-Daunorubicin-Small Interfering RNA Nanoassembly for Targeted Therapy of Acute Myeloid Leukemia.
Yang H, Yu X, Guo Z, Shi S, Wang J, Guo S, Hu B, Chai M, Wang Z, Barth S, Fan K, He H, Zhang M, Huang Y
Cyborg and bionic systems (Washington, D.C.) 2025;6:0436
Cyborg and bionic systems (Washington, D.C.) 2025;6:0436
A Hepatic Oxidative Metabolite of Palmatine Ameliorates DSS-Induced Ulcerative Colitis by Regulating Macrophage Polarization Through AMPK/NF-κB Pathway.
Huang QT, Ma XD, Zhang JN, Lin WX, Shen XX, Huang ZW, Zhang X, Wu XY, Dou YX, Su ZR, Su JY, Li YC, Liu YH, Xie YL, Lin RF, Huang HY, Zhang QH, Huang XQ
The American journal of Chinese medicine 2025;53(1):285-307
The American journal of Chinese medicine 2025;53(1):285-307
Quercetin, a Natural Dietary Flavonoid, Emerges a Novel USP7 Inhibitor with Anti-colorectal Cancer Effects.
Li X, Li Q, Huang Y, Zhou H, Yang Q, Kong L
Biological & pharmaceutical bulletin 2025;48(10):1485-1492
Biological & pharmaceutical bulletin 2025;48(10):1485-1492
Mycobacterial antigen Ag85B restrains Hodgkin lymphoma tumor growth by inhibiting autophagy.
Cheng Y, Shen Y, Zhang Y, Nuriding H, Wang X, Fan C, Maimaiti G, Liu YU, Yue Y, Li D, Yan M
Oncology research 2025;33(5):1173-1187
Oncology research 2025;33(5):1173-1187
Splicing factor PTBP1 promotes hepatocarcinogenesis via oncogenic splice-switching of MAPT.
Zheng W, Shang Y, DU K, Luo A, Pei L, Li M, Zhang G, Deng M
Oncology research 2025;33(5):1121-1133
Oncology research 2025;33(5):1121-1133
Qizhi Kebitong Formula Ameliorates Sciatic Nerve Injury in Streptozocin-induced Diabetic Mice through PERK/ATF4/CHOP Endoplasmic Reticulum Stress Signaling Pathway.
Yu H, Yang C, Wang G, Lv J, Li X, Qi W, Wang X
Current pharmaceutical design 2025;31(29):2370-2384
Current pharmaceutical design 2025;31(29):2370-2384
Hsa_piR_016975 Is a Novel Target of Nanotherapy that Boosts Hepatoma Progression and Sorafenib Resistance by Abating Maspin/GPX4-Mediated Ferroptosis.
Feng W, Xu J, Chen B, Liu J, Hu Y, Cao X, Qi J, Ju L, Shao J, Dong P, Chen L, Wang F
Biomaterials research 2025;29:0225
Biomaterials research 2025;29:0225
Ginsenoside Rh2-Pretreated Mesenchymal Stem Cell Exosomes Ameliorate Collagen-Induced Arthritis via N6-Methyladenosine Methylation.
Zhou Z, Wu S, Li Y, Shao P, Jiang J
Biomaterials research 2025;29:0220
Biomaterials research 2025;29:0220
A Novel Hypoxia-related lncRNA Risk Score Model for Prognosis Evaluation of Clear Cell Renal Cell Carcinoma.
Liu F, Li X, Zhou X, Tong H, Hu Z, Bai X, Gou X
Combinatorial chemistry & high throughput screening 2025;28(15):2589-2600
Combinatorial chemistry & high throughput screening 2025;28(15):2589-2600
A method for isolating and cryopreserving intact mitochondria with improved integrity and functionality.
Okutani A, Naima J, Ogihara A, Motoichi T, Ohsawa I, Ohta Y
Biophysics and physicobiology 2025;22(2):e220012
Biophysics and physicobiology 2025;22(2):e220012
Roxadustat: A catalyst for diabetic wound healing through re-epithelialization and angiogenesis.
Tang D, Lin Q, Xu K, Lu QP
CytoJournal 2025;22:90
CytoJournal 2025;22:90
DARS2 Promotes Bladder Cancer Progression by Enhancing PINK1-Mediated Mitophagy.
Li D, Su H, Deng X, Huang Y, Wang Z, Zhang J, Chen C, Zheng Z, Wang Q, Zhao S, Chen ZS, Chen H, Hou L, Tan W, Li F
International journal of biological sciences 2025;21(4):1530-1544
International journal of biological sciences 2025;21(4):1530-1544
Linking Cellular Senescence to Vascular Pathology: The Diagnostic Potential of Superoxide Dismutase 2 in Aortic Dissection.
Wu X, Qin J, Tang D, Wang X, Wang R, Li W, Zhang J, Lu X
Vascular health and risk management 2025;21:983-1005
Vascular health and risk management 2025;21:983-1005
Dietary DHA Regulated the Androgen Production in Male Chinese Tongue Sole Cynoglossus semilaevis.
Liu J, Ma Q, Zhang F, Gao Q, Zhang Z, Wei Y, Liang M, Xu H
Aquaculture nutrition 2025;2025:9318358
Aquaculture nutrition 2025;2025:9318358
Multiomics Identifies Potential Biomarkers in Ankylosing Spondylitis Bone Formation.
Yang L, Bo C, Chen M, Chen B, Zeng R, Zhou Y, Du H, He X
Human mutation 2025;2025:8771129
Human mutation 2025;2025:8771129
Imbalance of Bone Homeostasis Caused by Nrf2 Deficiency Leads to Bone Loss in OVX Rats.
Sun P, Wang Z, Chen S, Chen X, Zhou F, Zhang C, Yang J, Huang Y, Lin Y
Stem cells international 2025;2025:7214250
Stem cells international 2025;2025:7214250
Systematic Analysis of an Immune-Related Gene Signature for Predicting Prognosis and Immune Characteristics in Primary Lower Grade Glioma.
Hou L, Tian L, Li J, Zhang Z, Han X, Zhou H, Xue X
BioMed research international 2025;2025:6180391
BioMed research international 2025;2025:6180391
Elucidating the Therapeutic Mechanism of Danggui Liuhuang Decoction in Hyperthyroid Kidney Disease: An Integration of Network Pharmacology and Metabolomics.
Jiang Y, Wang Z, Zhao Y, Yu Q, Weng L, Xiao C
International journal of endocrinology 2025;2025:5513418
International journal of endocrinology 2025;2025:5513418
Astaxanthin Mitigates Dextran Sulfate Sodium-Induced Colitis in Mice by Repairing the Intestinal Barrier, Regulating Specific Intestinal Flora, and Reducing Inflammatory Cell Infiltration.
Shen G, Yu D, Xu L, Yang T
Journal of immunology research 2025;2025:3381950
Journal of immunology research 2025;2025:3381950
Identification of Core Senescence-Related Genes and Characterization of Comprehensive Immune Landscape in Intervertebral Disc Degeneration.
Xu Q, Lian Z, Wang A, Li D, Wang Y, Guo Y, Qin J, Wang J, Zhao S
International journal of genomics 2025;2025:2521994
International journal of genomics 2025;2025:2521994
Active peptides of TSP-1 inhibit retinal angiogenesis through the CD36 pathway in a rat model of choroidal neovascularization.
Li Y, Deng A, Jiao K, Yan J, Zuo W, Dong Y, Xu W, Li Y, Guo C, Chen M, Tian R, Hu Z
PloS one 2025;20(6):e0325661
PloS one 2025;20(6):e0325661
The up-regulation of TGF-β1 by miRNA-132-3p/WT1 is involved in inducing leukemia cells to differentiate into macrophages.
Wang Z, Wang C, Zhang D, Wang X, Wu Y, Sun R, Sun X, Li Q, Bi K, Jiang G
PloS one 2025;20(5):e0306150
PloS one 2025;20(5):e0306150
RETRACTED: Short communication: Upregulation of hypoxia/reoxygenation-induced Shc3 by downregulated miR-455-5p, suppresses trophoblast invasion and is associated with placental inflammation and angiogenesis in preeclampsia.
Gong HZ, Guan J, Pan YZ, Ding HJ, Shi AW, Gu N
PloS one 2025;20(1):e0314544
PloS one 2025;20(1):e0314544
ADH5 inhibits proliferation but promotes EMT in non-small cell lung cancer cell through activating Smad2/Smad3.
Tan X, Huang Y, Li X, Xu F, Xu X
Open life sciences 2025;20(1):20251148
Open life sciences 2025;20(1):20251148
Convallatoxin inhibits proliferation and angiogenesis of glioma cells via regulating JAK/STAT3 pathway.
Hao Z, Han Y, Bo Y, Cao L, Fang H, Zhang Y, Li Q
Open life sciences 2025;20(1):20221056
Open life sciences 2025;20(1):20221056
Gelatin/Poly (Lactic-Co-Glycolic Acid)/Attapulgite Composite Scaffold Equipped with Teriparatide Microspheres for Osteogenesis in vitro and in vivo.
Zhao Z, Feng X, Zhao Y, Song Z, Zhang R, Zhang K, He Y, Chen G, Zhang J, Wang W
International journal of nanomedicine 2025;20:581-604
International journal of nanomedicine 2025;20:581-604
Layered Double Hydroxide Nanoparticles Loaded with Resveratrol Inhibit Glycolysis and Show Efficacy in the Treatment of Breast Cancer.
Geng C, Yan L, Li Y, Li H, Ji Y, Xiao Y, Wang Z, Chen X, Chen C, Yang Q, Tang B, Wang W
International journal of nanomedicine 2025;20:3423-3444
International journal of nanomedicine 2025;20:3423-3444
TET1 Alleviates Cigarette Smoke Induced Bronchial Epithelial Cell Apoptosis Through Upregulating Nrf2.
Zhang ZX, Yu HD, Sai XY, Qin C, Ding Y, Bian T
International journal of chronic obstructive pulmonary disease 2025;20:3203-3215
International journal of chronic obstructive pulmonary disease 2025;20:3203-3215
Quercetin-Loaded Nanoparticle-Modified Decellularized Tissue-Engineered Vascular Graft Regulates Macrophage Polarization and Promotes In Vivo Graft Remodeling.
Wang T, He Z, Lu P, Liao S, Cheng S, Wang T, An Y, Cheng Z, Shu C
International journal of nanomedicine 2025;20:2761-2778
International journal of nanomedicine 2025;20:2761-2778
Honeysuckle-Derived Exosome-Like Nanovesicles Protect Against Acute Liver Failure by Modulating Gut Microbiota.
Li P, Tang Y, Chen Y, Fan W, Yao J, Yu K, Shan Y, Wang J, Ye XM, Zou H, Mou X
International journal of nanomedicine 2025;20:12975-12992
International journal of nanomedicine 2025;20:12975-12992
MXene-Mediated Nanocarrier Delivery Enhances the Chondroprotective Effects of Quercetin in Experimental Osteoarthritis.
Gan K, Li J, Zhang X, Feng Z, Liu J, Zhao F
International journal of nanomedicine 2025;20:11553-11567
International journal of nanomedicine 2025;20:11553-11567
Over-expressed Phospholamban in Cancer-associated Fibroblasts Is a Driver for CMS4 Subtype Colorectal Cancer Formation.
Li T, Fei Y, Sun X, Zhu J, Fang X, Meng F, Wang D, Zhang X, Liu C, Du Q
Cellular and molecular gastroenterology and hepatology 2025;19(9):101524
Cellular and molecular gastroenterology and hepatology 2025;19(9):101524
Hepatic Stellate Cell TM4SF1 Accelerates Hepatic Fibrosis Progression via Interacting With the Tyrosine Kinase c-Src.
Liu S, Tan P, Chen J, Huang Z, Ren B, Jiang Z, Gu B, Yu W, Sun L, Chen Y, Ruan J, Fu W
Cellular and molecular gastroenterology and hepatology 2025;19(10):101559
Cellular and molecular gastroenterology and hepatology 2025;19(10):101559
Integrating Clinical Multi-Omics, Machine Learning, and Molecular Docking Strategies to Reveal the Mechanism of Yiqi Huoxue Prescription in the Treatment of Ischemic Heart Failure.
Wei J, Qiao L, Yu P, Li Y, Li X, Li M, Zhu X, Wu W, Wang A, Zhang Y, Li L, Li B, Zhao Q, Yu R, Li Y, Dong Z, Nie S, Wang Y, Wang X, Zhu M
Drug design, development and therapy 2025;19:9853-9878
Drug design, development and therapy 2025;19:9853-9878
Allicin Aplealleviates Gouty Arthritis by Regulating the Gut-Joint Axis, Reducing XOD Activity, Inhibiting Oxidative Stress, and Suppressing NLRP3 Inflammasome Activation.
Wu H, Pang MM, Li YL, Hong JH, Liu PM, Bian M, Yang JJ
Drug design, development and therapy 2025;19:7887-7907
Drug design, development and therapy 2025;19:7887-7907
Puerarin Ameliorates the Ferroptosis in Diabetic Liver Injure Through the JAK2/STAT3 Pathway Inhibition Based on Network Pharmacology and Experimental Validation.
Fan X, Liu S, Yu J, Hua J, Feng Y, Wang Z, Shen Y, Lan W, Wang J
Drug design, development and therapy 2025;19:737-757
Drug design, development and therapy 2025;19:737-757
Magnesium Isoglycyrrhizinate Alleviates Alectinib-Induced Hepatotoxicity by Inhibiting Mitochondrial Damage-Mediated Pyroptosis.
Chen Y, Wang C, Wu Y, Zeng Y, Xie S, Weng J, Guo L, Fu J, Zhou T, Zhang X, Zhou Z
Drug design, development and therapy 2025;19:6219-6233
Drug design, development and therapy 2025;19:6219-6233
Mechanism of the Traditional Chinese Medicine Simiao Biejia Decoction Improves the Diabetes Mellitus-Induced Erectile Dysfunction in Rats.
Liu Y, Sun D, Xing D, Rui Y, Jin Y, Wang P, Cai B, Li C, Gao C, Cui Y, Jin B
Drug design, development and therapy 2025;19:2609-2628
Drug design, development and therapy 2025;19:2609-2628
TRAP1 Improves Diabetic Retinopathy by Preserving Mitochondrial Function.
Li Y, Xu W, Zhao G, Guo Y, Wang L, Du Q, Fei Y, Hu X, Hu H, Chen L, Xu Y
Clinical ophthalmology (Auckland, N.Z.) 2025;19:2343-2362
Clinical ophthalmology (Auckland, N.Z.) 2025;19:2343-2362
Research on the correlation between gut microbiota and brain cognitive function under chronic hypoxia at high altitude.
Zeng F, Li H, Ma Y, Ma S
Frontiers in neuroscience 2025;19:1600069
Frontiers in neuroscience 2025;19:1600069
Disulfidptosis-Related Genes as Novel Biomarkers and Therapeutic Targets in Dilated Cardiomyopathy.
Bo X, Fan J, Xu S, Zeng Y, Xu A, Wang X, Wang H, Kang P, Fu Y, Fan H, Tan X, Zhou Y
Journal of inflammation research 2025;18:9967-9988
Journal of inflammation research 2025;18:9967-9988
Xuebijing Injection Alleviates Sepsis-Induced Acute Lung Injury by Inhibition of Cell Apoptosis and Inflammation Through the Hippo Pathway.
Ling B, Ji J, Huang Q, Xu Y, Hu Y, Pan S, Liu S, Hua T, Tang L, Yang M
Journal of inflammation research 2025;18:7717-7733
Journal of inflammation research 2025;18:7717-7733
AIM2-Driven Inflammation in Periodontitis: Mechanisms and Systemic Implications.
Fan Z, Chen R, Xie X, Chen Z, Yang D, Hao C, Wang S
Journal of inflammation research 2025;18:6983-6997
Journal of inflammation research 2025;18:6983-6997
COMMD1 Regulates Osteoclast Differentiation in Talaromyces marneffei-Induced Osteomyelitis via the NF-κB Pathway.
Zhang Y, Yang F, Zhao W, Wei R, Zeng G, Zong S
Infection and drug resistance 2025;18:6079-6092
Infection and drug resistance 2025;18:6079-6092
Modified Xi-Jiao-Di-Huang Decoction Alleviates Sepsis via Regulating Macrophage Polarization by Inhibiting the PIM2/NF-κB Pathway.
Ge F, Tian F, Zhu Y, Yan Q, Sun Q, Lu J
Journal of inflammation research 2025;18:5017-5030
Journal of inflammation research 2025;18:5017-5030
Astragaloside IV Improves Cognitive Impairment by Reducing β-Amyloid and Tau Protein Deposition in Hippocampal Tissue of db/db Mice: A PET/CT Imaging-Based Study.
Jiang L, Lu Y, Yin P, Liu D, Duan C, Wang Y
Diabetes, metabolic syndrome and obesity : targets and therapy 2025;18:3477-3490
Diabetes, metabolic syndrome and obesity : targets and therapy 2025;18:3477-3490
Association Between Proteasome 26S Subunit, Non-ATPase 3 Methylation and Insulin β Cell Apoptosis in Type 2 Diabetic Mellitus.
Huang G, He G, Chen S, Mai L
Diabetes, metabolic syndrome and obesity : targets and therapy 2025;18:3203-3214
Diabetes, metabolic syndrome and obesity : targets and therapy 2025;18:3203-3214
MCC950 Alleviates Experimental Autoimmune Neuritis by Inhibiting NLRP3 Inflammasome Activity and Down-Regulating Interleukin-23/Interleukin-17 Axis Expression.
Li Y, Li X, Gu T, Wang L, Song M, Yang L, Huang Q, Yang J
Journal of inflammation research 2025;18:17113-17127
Journal of inflammation research 2025;18:17113-17127
Angiotensin-(1-7) Inhibits Angiogenesis and Alleviates Joint Damage in CIA Mice via the Hippo-YAP Pathway.
Zhang S, Sheng M, Yu D, Qian K, Zhang Y, Huang W, Ren F, Tang L
Journal of inflammation research 2025;18:12401-12419
Journal of inflammation research 2025;18:12401-12419
Low-Frequency (1 Hz) Repetitive Trans-Spinal Magnetic Stimulation Attenuates NLRP3-Driven Neuroinflammation and Enhances Motor Recovery in Spinal Cord-Injured Mice.
Song H, Yang Y, Huang L, Li Y, Sun B, Yu Z, Zhang M, Yang D
Journal of inflammation research 2025;18:11263-11284
Journal of inflammation research 2025;18:11263-11284
Comprehensive Analysis of Ferroptosis Markers in Lupus Nephritis Based on Bioinformatics Analysis and Experimental Validation.
Zhang S, Hu W, Huang C, Lin X, Chen X
Journal of inflammation research 2025;18:10855-10871
Journal of inflammation research 2025;18:10855-10871
VOPP1 as a Novel Susceptibility Gene in Rheumatoid Arthritis: Insights Into Its Mechanisms From Mendelian Randomization and Experimental Validation.
Wu W, Cai H, Nan Y, Tang J, Wang Y
Journal of inflammation research 2025;18:10341-10354
Journal of inflammation research 2025;18:10341-10354
Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis.
Zhao S, Chen R, An Y, Zhang Y, Ma C, Gao Y, Lu Y, Yang F, Bai X, Zhang J
Frontiers in aging neuroscience 2025;17:1522073
Frontiers in aging neuroscience 2025;17:1522073
Baicalein ameliorates cognitive decline induced by chronic cerebral hypoperfusion through the SIRT1-mediated Notch1 pathway to improve angiogenesis and suppress neuroinflammation.
Li M, Song J, Niu X, Mo F, Xie X, Li X, Yin Y, Wang T, Song X, Liu J, Lv P
Frontiers in aging neuroscience 2025;17:1521353
Frontiers in aging neuroscience 2025;17:1521353
Network Pharmacology and Experimental Validation-based Investigation of the Underlying Mechanism of Yi-Yi-Fu-Zi-Bai-Jiang-San of Nasopharyngeal Carcinoma.
Lin Z, Huang T, Han B, Tao Z, Chen X
Journal of Cancer 2025;16(7):2212-2232
Journal of Cancer 2025;16(7):2212-2232
Implication of CDKN2A in cuproptosis through defining cuproptosis-related gene signature in ovarian cancer.
Zhang B, Yang Z, Zheng Y, He Y, Yan Y, Song J, Wang F, An R
Journal of Cancer 2025;16(11):3355-3371
Journal of Cancer 2025;16(11):3355-3371
Machine learning-derived cellular senescence index for predicting prognosis and drug sensitivity in patients with renal cell carcinoma.
Meng L, Zhang H, Qiu Y, Zhu X, Ji X, Wang B, Zhang G, Xue Y, Wang C
Frontiers in immunology 2025;16:1727099
Frontiers in immunology 2025;16:1727099
A stage specific NETs-related signature in alcoholic steatohepatitis: from molecular subtyping to therapeutic vulnerabilities.
Gao W, Lin Z, Bao Y, Liu M, Ma G, Chen X, Yu S, Zeng Y
Frontiers in immunology 2025;16:1711388
Frontiers in immunology 2025;16:1711388
Xiaoyao Pill alleviates ulcerative colitis by inhibiting ferroptosis of enterocytes via activating Nrf2/Gpx4 signaling pathway.
Zhou Z, Xing X, Zhang R, Zhang X
Frontiers in pharmacology 2025;16:1702452
Frontiers in pharmacology 2025;16:1702452
Association of genetically instrumented HMGCR inhibition with the therapeutic role of prostate cancer: a Mendelian randomization study and supporting in vitro experiments.
Hao X, Mu J
Frontiers in pharmacology 2025;16:1701869
Frontiers in pharmacology 2025;16:1701869
Effect of gentiopicroside on endogenous formaldehyde homocysteine-pathway related proteins in rats with non-alcoholic steatohepatitis.
Chen J, Zuo H, Jiao Y, Zhao H, Ma X, Xiao Y, Li X, Zhao W, Shi A, Chen W
Frontiers in pharmacology 2025;16:1700101
Frontiers in pharmacology 2025;16:1700101
Pan-cancer analysis and experimental verification of its roles and clinical significance of SLC2A3 in kidney renal clear cell carcinoma.
Lyu Z, Zhang X, Yuan H, Yang Q, Yang Y, Zhao Z, Wang G, Bi L
Frontiers in immunology 2025;16:1694137
Frontiers in immunology 2025;16:1694137
Coreopsis tinctoria Nutt. attenuates ultraviolet A photodamage by suppressing endoplasmic reticulum stress-induced apoptosis via Nrf2 crosstalk.
Liang L, Nie X, Zhao N, Li M, Li M, Li Z, Wu M, Wu X, Lee CL, Shu P, Zhong J
Frontiers in pharmacology 2025;16:1686234
Frontiers in pharmacology 2025;16:1686234
Thymoquinone and aerobic exercise mitigate HFpEF-induced cardiac injury via Apaf1/Cycs axis regulation.
Pei Z, Gao S, Yang J, Liu C, Pan Y
Frontiers in pharmacology 2025;16:1672570
Frontiers in pharmacology 2025;16:1672570
CGRP restrains CD4(+) T cell responses and allergic sensitization.
Li X, Zhang Y, Chen W, Meng Q, Huang A, Pan J, Chen D, Xiao Y, Wei J, Sun H, Liu Q
Frontiers in immunology 2025;16:1671269
Frontiers in immunology 2025;16:1671269
Sancai Lianmei granules ameliorate neuron injury in diabetic ischemic stroke rats by inhibiting oxidative stress and inflammation.
Zhu C, Chen D, Li Z, Wang Y, Han X, Chen Q
Frontiers in endocrinology 2025;16:1666597
Frontiers in endocrinology 2025;16:1666597
circWWC3 enhances the progression of triple-negative breast cancer by interacting with vimentin to regulate the secretion of CSF2.
Wu M, Du Y, Dong Y, Zheng Y, Gu L, Tang X, Yan L, Ji H, Sang Y, Liu F
Frontiers in immunology 2025;16:1665608
Frontiers in immunology 2025;16:1665608
Exploring the mechanism of Qingre Yishen Xiaozheng formula in treating diabetic kidney disease via the HIF-1α/HO-1 signaling pathway: an integrated network pharmacology and experimental study.
Han F, Shou J, Wang Y, Tian Z, Zheng H, Liu L, Liu W
Frontiers in pharmacology 2025;16:1661050
Frontiers in pharmacology 2025;16:1661050
Single-cell profiling uncovers PTPRG-driven stemness in malignant plasma cells and signatures of treatment failure in multiple myeloma.
Tan J, Zhong J, He Y, Xu Y, Chen C, Xiong D
Frontiers in immunology 2025;16:1658028
Frontiers in immunology 2025;16:1658028
Integrative bioinformatic and experimental analysis reveals prognostic and immunological roles of MEX3 family genes in glioma.
Zhang X, Shang H, Chu T, Sha K
Frontiers in immunology 2025;16:1654036
Frontiers in immunology 2025;16:1654036
Inhibition of HMGB1/NF-κB signaling restores Th17/Treg balance via dendritic cell modulation in liver transplant rejection.
Li L, Wang J, Huang L, Chen Y, Chen L
Frontiers in immunology 2025;16:1649366
Frontiers in immunology 2025;16:1649366
Isorhamnetin attenuates renal interstitial fibrosis by targeting TWEAK/Fn14-mediated epithelial-mesenchymal transition.
Chen Y, Luo W, Guan H, Chen Z, Chen Z, Xiao L, Xu W, Huang M, Lin Y, Zhang Y, Peng W, Nan L
Frontiers in immunology 2025;16:1649327
Frontiers in immunology 2025;16:1649327
Zuoqing granules attenuate ulcerative colitis via macrophage polarization modulation: involvement of the PPAR-γ/NF-κB/STAT1 signaling axis.
Deng H, Li M, Fang X, Tang K, Xu S, Ding R, Li Z
Frontiers in pharmacology 2025;16:1646545
Frontiers in pharmacology 2025;16:1646545
Sarsasapogenin protects hair cells from cisplatin-induced ototoxicity by attenuating apoptosis and ferroptosis via alleviating oxidative stress.
Chen Z, Xie T, Chen C, Lin T, Wu X, Chen Y, Lin Y, Luo X, Zeng C, Lin C
Frontiers in pharmacology 2025;16:1641174
Frontiers in pharmacology 2025;16:1641174
Ailanthone induces apoptosis in U-2OS cells through the endoplasmic reticulum stress.
Zhang Y, Wu T, Li C, Luo N, Wang J, Li J, Tian M, Liu L, Li R, Zhang J
Frontiers in immunology 2025;16:1633643
Frontiers in immunology 2025;16:1633643
Comprehensive analysis of metabolic patterns in renal cell carcinoma: implications for prognosis and treatment.
Wang Y, Li P, Feng T, Chen Y, Liu W, Ge Q, Zhang Q
Frontiers in immunology 2025;16:1630053
Frontiers in immunology 2025;16:1630053
Reciprocal activation between M1 macrophages and trophoblasts through CXCL9/STAT1/ZEB1/CCL2 axis promotes recurrent spontaneous abortion.
Yan S, Wang X, Wu Q, Ding J, Qiu H
Frontiers in immunology 2025;16:1629370
Frontiers in immunology 2025;16:1629370
Vitamin D ameliorates prediabetic cardiac injure via modulation of the ErbB4/ferroptosis signaling axis.
Miao Y, Zhang Y, Zhang L, Chen H, Tang L, Li W, Gu C, Lang L, Li X, Song H
Frontiers in immunology 2025;16:1626295
Frontiers in immunology 2025;16:1626295
Bifidobacterium depletion promotes goiter via gut-thyroid axis: evidence from Mendelian randomization and experimental validation.
Liao W, Jiang Y, Zhang J, Wu Y, Yu X, Chen S, Liu H, Xiu L, Zhong G
Frontiers in microbiology 2025;16:1621167
Frontiers in microbiology 2025;16:1621167
Inhibition of CYP450 family 1 subfamily B member 1 (CYP1B1) expression in macrophage reduces the inflammatory response in type 2 diabetes mellitus combined with tuberculosis.
Du Q, Liu K, Li Y, Wang X, Liu X, Zhao J, Wang X
Frontiers in endocrinology 2025;16:1617292
Frontiers in endocrinology 2025;16:1617292
Fucoidan from Fucus vesiculosus alleviates MetALD via promoting HIF-1α ubiquitination to suppress peripheral monocyte infiltration.
Li L, Luo J, Wang D, Chang Y, Duan C, Zuo D
Frontiers in pharmacology 2025;16:1617175
Frontiers in pharmacology 2025;16:1617175
Risk scoring model for lung adenocarcinoma based on PD-L1 related signature reveals prognostic predictability and correlation with tumor immune microenvironment genes was constructed.
Li-Fei M, Ren SM, Wang J, Zhao WJ, Chen J, Hu WT
Frontiers in immunology 2025;16:1601982
Frontiers in immunology 2025;16:1601982
The function of CD164 in breast cancer and its possibility as a molecular biomarker: bioinformatics analysis and experimental validation.
Li M, Mao J, Wang G, Chen J, Hong J, Wang X, Liang B, Song D
Frontiers in immunology 2025;16:1601547
Frontiers in immunology 2025;16:1601547
T cell-mediated immune surveillance conferred by latent Epstein-Barr virus genes suppresses a broad spectrum of tumor formation through NKG2D-NKG2DL interactions.
Jin Y, Guo Y, Kawano Y, Sasatani M, Ohki S, Yamane K, Ota Y, Tamura Y, Sotomaru Y, Baba Y, Yasuda T
Frontiers in immunology 2025;16:1597731
Frontiers in immunology 2025;16:1597731
Tetramethylpyrazine enhances neuroprotection and plasticity in cerebral ischemia-reperfusion injury via RhoA/ROCK2 pathway inhibition.
Zhang Y, Zhang X, Shi X, Liao W, Lin J
Frontiers in pharmacology 2025;16:1594283
Frontiers in pharmacology 2025;16:1594283
Identification of mitophagy-related biomarkers in severe acute pancreatitis: integration of WGCNA, machine learning algorithms and scRNA-seq.
Xie X, Wang Z, Zhang H, Lu J, Cao F, Li F
Frontiers in immunology 2025;16:1594085
Frontiers in immunology 2025;16:1594085
Enrichment of short-chain fatty acid-producing bacteria by pH-responsive sodium alginate and chitosan-encapsulated quercetin.
Bai Q, Zhao Z, Duan Y, Cai R, Chen Y, Zhou C, Tian X, Yang Y, Wu H, Li M, You J, Song Q, Dong H, Liu T
Frontiers in microbiology 2025;16:1594012
Frontiers in microbiology 2025;16:1594012
Toll-like receptor 3 activation enhances antitumor immune response in lung adenocarcinoma through NF-κB signaling pathway.
Li A, Luo M, Liu X, Wu H, Liu X, Zhang Z, Zhang X
Frontiers in immunology 2025;16:1585747
Frontiers in immunology 2025;16:1585747
Lactylation prognostic signature identifies DHCR7 as a modulator of chemoresistance and immunotherapy efficacy in bladder cancer.
Zhao Y, Xing Z, Zhao Y, Xu H, Liu R, Yang T, Wang Y, Zhu X
Frontiers in immunology 2025;16:1585727
Frontiers in immunology 2025;16:1585727
Identification and evaluation of a pinocembrin analog as a TRPV1 inhibitor with analgesic properties in murine pain models.
Chen H, Li G, Deng L, Xu N, Lee SM, Nie X, Bian JS
Frontiers in pharmacology 2025;16:1585181
Frontiers in pharmacology 2025;16:1585181
Identification of CTSC-driven progression in ESCC by single-cell sequencing and experimental validation.
Sui X, Jia Y, Li J, Xu J, Wang W, Qin Y
Frontiers in immunology 2025;16:1585139
Frontiers in immunology 2025;16:1585139
Investigating the regulation of the miR-199a-3p/TGF-β/Smad signaling pathway by BSHXF drug-containing serum combined with ADSCs for delaying intervertebral disc degeneration.
Liu E, Sun Y, Yang L, Jiang H, Sun F, Chen L, Duan J, Yang S
Frontiers in pharmacology 2025;16:1583635
Frontiers in pharmacology 2025;16:1583635
In vitro study: HIF-1α-dependent glycolysis enhances NETosis in hypoxic conditions.
Ye Y, Wang Y, Xu Q, Liu J, Yang Z, Wuren T, Ge RL
Frontiers in immunology 2025;16:1583587
Frontiers in immunology 2025;16:1583587
SIRT2-dependent CPT1A deacetylation in macrophages inhibits periodontitis.
Jiang Y, Yao X, Jiang Z, Liu X, Sun B, Guan Z, Zhou L, Li H
Frontiers in pharmacology 2025;16:1574141
Frontiers in pharmacology 2025;16:1574141
Investigation of Fructus sophorae extract's therapeutic mechanism in atrophic vaginitis based on network pharmacology and experimental validation.
Zheng J, Wang W, Song W, Zhang Y, Yao M, Wang G, Huang Z, Li F, Ren J, Lin L, Fan X, Liu J
Frontiers in pharmacology 2025;16:1571976
Frontiers in pharmacology 2025;16:1571976
Molecular characteristics and cancer immunity of LRP1B and its relationship with the Hedgehog signaling pathway in colorectal cancer.
Liu Y, Zhong Y, Sang Y, Zhu S, Xu K, Zhu X, Cui X, Liu X, Wang X, Chen H, Jing C, Chong W, Li L
Frontiers in immunology 2025;16:1567102
Frontiers in immunology 2025;16:1567102
Trapidil attenuates diabetic cardiomyopathy via GPX3/Nrf2-mediated inhibition of myocardial pyroptosis.
Wang Z, Sun Y, Wang J, Xu Q, Wang L, Zhang Q, Song J, Wang Y, Qi Z
Frontiers in pharmacology 2025;16:1566622
Frontiers in pharmacology 2025;16:1566622
Wuling capsule alleviates hyperuricaemia and protects UA- injured HK-2 cells by regulating uric acid transporter proteins.
Li N, Liu H, Song Z, Zhou R, Tang Z, Xu H, Shi X, Liu Y, Ni J
Frontiers in pharmacology 2025;16:1563676
Frontiers in pharmacology 2025;16:1563676
Integrative analysis of single-cell and bulk RNA sequencing reveals the oncogenic role of ANXA5 in gastric cancer and its association with drug resistance.
Chen D, Zhang P, Gong L, Wei H, Yu G, Zhang T, Bai C
Frontiers in immunology 2025;16:1562395
Frontiers in immunology 2025;16:1562395
Acetylcholine from tuft cells promotes M2 macrophages polarization in Hirschsprung-associated enterocolitis.
Zheng Z, Lin L, Lin H, Zhou J, Wang Z, Wang Y, Chen J, Lai C, Li R, Shen Z, Zhong M, Xie C, Chen Y, Zhang X, Guo Z, Dong R, He S, Chen F
Frontiers in immunology 2025;16:1559966
Frontiers in immunology 2025;16:1559966
Licorice attenuates cisplatin-induced hepatotoxicity by alleviating endoplasmic reticulum stress and apoptosis.
Li J, Yang X, Lian X, Li B, Ma Q, Yang L, Gao G, Deng Y, Yang Z
Frontiers in pharmacology 2025;16:1557125
Frontiers in pharmacology 2025;16:1557125
IGFBP5 mediates the therapeutic effect of isoliquiritigenin in myocardial ischemia-reperfusion injury via AKT/GLUT4 regulated insulin resistance.
Bai J, Yang SY, Yu SM, Cao Y, Ma CH, Hu XY, Chen X, Song YN, Chen HJ
Frontiers in pharmacology 2025;16:1544869
Frontiers in pharmacology 2025;16:1544869
Wharton's jelly-derived mesenchymal stem cells ameliorate high altitude-induced heart injury by promoting type 2 macrophage polarization via COX2-PGE2 pathway.
Zhang W, Zhao L, Cui J, Zhang Y, Li D, Hong Z, Liu J, Wang S, Zhang N, Li Y, Chen Y
Frontiers in immunology 2025;16:1538046
Frontiers in immunology 2025;16:1538046
Clusterin ameliorates diabetic atherosclerosis by suppressing macrophage pyroptosis and activation.
Xuan L, Ren L, Kang X, Chang R, Zhang W, Gong L, Liu L
Frontiers in pharmacology 2025;16:1536132
Frontiers in pharmacology 2025;16:1536132
Therapeutic potential of isochlorogenic acid A from Taraxacum officinale in improving immune response and enhancing the efficacy of PD-1/PD-L1 blockade in triple-negative breast cancer.
Wang T, Sun J, Wang L, Lin Y, Wu Z, Jia Q, Zhang S, An J, Ma X, Wu Q, Su Z, Wang H
Frontiers in immunology 2025;16:1529710
Frontiers in immunology 2025;16:1529710
Targeted inhibitors of S100A9 alleviate chronic pancreatitis by inhibiting M2 macrophage polarization via the TAOK3-JNK signaling pathway.
Tao X, Wu Y, Guo F, Lv L, Zhai X, Shang D, Yu Z, Xiang H, Dong D
Frontiers in immunology 2025;16:1526813
Frontiers in immunology 2025;16:1526813
Bletilla oligosaccharides improved 5-fluorouracil-induced intestinal mucositis in mice by activating NF-κB signalling pathway and regulating intestinal microbiota.
Yin Q, Li X, Xiong Y, Jiang Y, Ma S, Qian G
Frontiers in pharmacology 2025;16:1526274
Frontiers in pharmacology 2025;16:1526274
An integrative pharmacology-based study on the pharmacological activity and mechanism of xiaoji-chenpi formula (XCF) against MAFLD.
Liang S, Dong Y, Chang Z, Guo P, Jia J, Yang G, Chen Y, Dong L, Xu X, Cai T, Li T, Fang Y, Sun W, Li L, Wang C, Song X
Frontiers in pharmacology 2025;16:1521111
Frontiers in pharmacology 2025;16:1521111
Regulatory mechanism of ABCB1 transcriptional repression by HDAC5 in rat hepatocytes under hypoxic environment.
Wei Z, Mu H, Qiu F, Zhao M, Zhang X, Li W, Jia H, Wang R
Frontiers in physiology 2025;16:1520246
Frontiers in physiology 2025;16:1520246
Hydrogen sulfide alleviates high-salt-stimulated myocardial fibrosis through inhibiting hypoxia-inducible factor-1α.
Peng Q, Huang P, Lv B, Tang C, Jin H, Huang Y
Frontiers in pharmacology 2025;16:1502269
Frontiers in pharmacology 2025;16:1502269
Molecular mechanism underlying cardioprotective effect of dehydroepiandrosterone on endoplasmic reticulum stress induced apoptosis in human vascular smooth muscle cells and human umbilical vein endothelial cells.
Zhu Y, Wei J, Yang X, Zhu W
Frontiers in pharmacology 2025;16:1496393
Frontiers in pharmacology 2025;16:1496393
Identification and validation of neutrophil-related biomarkers in acute-on-chronic liver failure.
Lin W, Chen Y, Lu M, Peng C, Chen X, Liu X, Wang Y
Frontiers in immunology 2025;16:1477342
Frontiers in immunology 2025;16:1477342
Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.
Wang L, Li H, Guo X, Wang X
Frontiers in physiology 2025;16:1475441
Frontiers in physiology 2025;16:1475441
A strategy targeting ferroptosis for mitochondrial reprogramming and intervertebral disc degeneration therapy.
Wu T, Teng Y, Song D, Yang Y, Shen H, Sun X, Chen R, Zhao L, Zhong X, Yan Q, Niu J, Ge J, Cheng L, Zou J
Theranostics 2025;15(17):9159-9178
Theranostics 2025;15(17):9159-9178
Calcium dysregulation disrupts mitochondrial homeostasis by interfering AMPK/Drp1 pathway to aggravate plaque progression and instability.
Hu P, Liu M, Wu T, Zhang Y, Liu C, Wang L, Zhang W, Que Y, You J, Yu W, Tong X
Theranostics 2025;15(15):7567-7583
Theranostics 2025;15(15):7567-7583
Autophagy inhibitor-sensitized artificially activated neutrophils against hepatocellular carcinoma.
Yang C, Yang H, Mao Z, Wang W, Ding Y
Theranostics 2025;15(14):7197-7218
Theranostics 2025;15(14):7197-7218
Human fibrosarcoma cells selected for ultra-high doxorubicin resistance, acquire trabectedin cross-resistance, remain sensitive to recombinant methioninase, and have increased c-MYC expression.
Morinaga S, Han Q, Mizuta K, Kang BM, Bouvet M, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Higuchi T, Tsuchiya H, Demura S, Hoffman RM
Frontiers in oncology 2025;15:1704021
Frontiers in oncology 2025;15:1704021
M2-type macrophage nanovesicles regulate the inflammatory response after necrotizing enterocolitis by inducing M1 to M2-like macrophage polarization.
Liu C, Gong J, Zhang L, Wang Y, Huang Y, Ju R
Frontiers in cellular and infection microbiology 2025;15:1664897
Frontiers in cellular and infection microbiology 2025;15:1664897
CDK1-driven phosphorylation networks promote glioblastoma progression via MAP1B-mediated microtubule destabilization.
Li JT, Li MD, Guo YJ, Li ZX, Qian RJ, Ma CX
Frontiers in oncology 2025;15:1646698
Frontiers in oncology 2025;15:1646698
Construction of a glycosylation-related prognostic signature for predicting prognosis, tumor microenvironment, and immune response in soft tissue sarcoma.
Yuan N, Zhang J, Yuan J, Xie Z, Gao Y, Raza M, Gao Y, Zuo G
Frontiers in oncology 2025;15:1636830
Frontiers in oncology 2025;15:1636830
LILRA5(+) macrophages drive early oxidative stress surge in sepsis: a single-cell transcriptomic landscape with therapeutic implications.
Xu P, Li H, Tao Z, Zhang Z, Wang X, Zhang C
Frontiers in cellular and infection microbiology 2025;15:1606401
Frontiers in cellular and infection microbiology 2025;15:1606401
Upregulation of stomatin is associated with poor prognosis and promotes tumor progression of orbital diffuse large B-cell lymphoma.
Chen W, Chi J, Song W, Li X, Ma J, Liu X, Xiao L, Zhu W
Frontiers in oncology 2025;15:1596614
Frontiers in oncology 2025;15:1596614
The anti-inflammatory effects of oridonin in resisting esophageal cancer.
Peng M, Zhang X, Yang L, Liu B
Frontiers in oncology 2025;15:1585057
Frontiers in oncology 2025;15:1585057
SATB2 promotes radiation resistance of esophageal squamous cell carcinoma by regulating epithelial-to-mesenchymal transition via the Wnt/β-catenin pathway.
Lin C, Wu Y, Qian Y, Li J, He Y, Yu H, Xie C, Su H
Frontiers in oncology 2025;15:1543426
Frontiers in oncology 2025;15:1543426
To explore the prognostic efficacy and mechanism of ABCC5 clinical scoring model in hepatocellular carcinoma.
Deng Y, Yang N, Huang C, Long M, Wu J, Mo K, Li Z
Frontiers in oncology 2025;15:1519533
Frontiers in oncology 2025;15:1519533
The 12-LOX/12-HETE/GPR31 metabolic pathway promotes tumor-associated macrophage M2 polarization mediated pancreatic cancer development.
Yang Y, Wang Y, Wu J, Tan C, Huang L
PeerJ 2025;13:e19963
PeerJ 2025;13:e19963
Integrative pan-cancer analysis of UCP family and experimental validation identifies UCP2 as a potential therapeutic target for glioma.
Guo W, Chen J, Li S, Zeng X, Wu X
Frontiers in cell and developmental biology 2025;13:1662654
Frontiers in cell and developmental biology 2025;13:1662654
Aquaporin 2 is differentially expressed in granulosa cells of various stages of human follicles and is regulated by luteinizing hormone.
Zheng Z, Tan J, Chen M, Zhang X, Liu S, Wen Y, Long L, Zhou C, Li Y
Frontiers in cell and developmental biology 2025;13:1647476
Frontiers in cell and developmental biology 2025;13:1647476
Induced neural stem cells ameliorate blood-brain barrier injury by modulating the calcium signaling pathway of astrocyte in cerebral ischemia-reperfusion rats.
Liang X, Cao C, Liu N, Chen D, Liu T, Ma H, Liu J, Wu T, Niu J
Frontiers in cell and developmental biology 2025;13:1611226
Frontiers in cell and developmental biology 2025;13:1611226
Linoleic acid metabolite 13-Hydroxyoctadecadienoic acid as a biphasic ferroptosis modulator in granulosa cells: multi-omics analysis of ovine atretic follicles.
Song Y, Hai E, He L, Zhang N, Zhang N, Wang J, Sun Y, Zeng D, Zhang J
Frontiers in cell and developmental biology 2025;13:1610621
Frontiers in cell and developmental biology 2025;13:1610621
SNHG12 downregulation induces follicular dysplasia by modulating the glycolysis of granulosa cell in polycystic ovary syndrome.
Yan S, Qu B, Chen Y, Wu Q, Ding J, Qiu H
Frontiers in cell and developmental biology 2025;13:1585987
Frontiers in cell and developmental biology 2025;13:1585987
Exploring the therapeutic mechanism of curcumin in spinal cord injury treatment based on network pharmacology, molecular dynamics simulation, and experimental validation.
He Y, Lu J, Luo Y, Pang R, Hu X, Ding L, Xiao H, Wang Y, Wang W
Frontiers in chemistry 2025;13:1568551
Frontiers in chemistry 2025;13:1568551
Shockwave-driven activation of endoplasmic reticulum stress in osteoblasts to enhance bone formation under osteoporotic conditions.
Luo D, Chen Q, Xiao Z, Feng C, Hu R, Wang Y, Zhu C, Yang X, Liu L, Li X, Zhu X, Song Y, Zhang X
Regenerative biomaterials 2025;12:rbaf069
Regenerative biomaterials 2025;12:rbaf069
JAK-centric explainable few-shot gene-expression diagnosis framework for alopecia via MultiPLIER priors and relation-style set-to-set comparison.
Yu N, Ran L, Gong X, Teng J, Liu S, Song Z
Frontiers in molecular biosciences 2025;12:1753206
Frontiers in molecular biosciences 2025;12:1753206
1-Deoxynojirimycin with theaflavins ameliorates high-fat diet-induced insulin resistance in mice by modulating the gut microbiota.
Di Q, Yang T, Zhao Y, Li W, Qu C, Zhang J, Zhu Y, Song C, Na L
Frontiers in nutrition 2025;12:1690747
Frontiers in nutrition 2025;12:1690747
Multi-targeted inhibition of NF-κB signaling underlies the anti-osteoarthritic effects of BGJXF and its key component dehydrocorydaline.
Shen J, Bin Z, Shen Y, Xie F, Zhang X, Tan X, Xu H
Frontiers in medicine 2025;12:1676071
Frontiers in medicine 2025;12:1676071
Bioinformatics and experimental validation of ferroptosis-related genes in steroid-induced osteonecrosis of the femoral head.
Guo MG, Yang CF, Yuan F, Yang T, Luo PY, He YB, Yang S, Chen F, Li W, Feng ZW
Frontiers in molecular biosciences 2025;12:1578755
Frontiers in molecular biosciences 2025;12:1578755
Aqueous extract of Solanum americanum Mill. relieves functional constipation by modulating the enteric nervous system and gut micro-ecosystems.
Gao X, Li Y, Hu Y, Yang W, Peng L, Sheng J, Tian Y, Yao L, Zhao Y
Frontiers in nutrition 2025;12:1573516
Frontiers in nutrition 2025;12:1573516
Case Report: A FBN1 frameshift-and-nonsense mutation and aortic dissection in Marfan syndrome.
Su C, Zeng L, Lu H, Wang Z, Wei M
Frontiers in cardiovascular medicine 2025;12:1533138
Frontiers in cardiovascular medicine 2025;12:1533138
A pectic polysaccharide from Lycium ruthenicum Murray alleviates dextran sulfate sodium-induced colitis in mice.
Dong D, Wang H, Bi H, Li Y, Gao T, Feng J, Li G, Guo S, Yuan H, Ni W
Current research in food science 2025;10:100955
Current research in food science 2025;10:100955
Sestrin2 Regulates Mitochondrial Function and Autophagy via Nrf2/SIRT3 Signaling to Ameliorate Hypoxia/Reoxygenation-Induced Rat's Cardiomyocyte Injury.
Liu T, Kong J, Li Z, Xi S, Liu L
Drug development research 2025 Sep;86(6):e70150
Drug development research 2025 Sep;86(6):e70150
STAT1-IFITM3 promotes autophagy in epithelial cells to control Cryptosporidium parvum infection.
Cui L, Li T, Zhang J, Shen Y, Cao J
Life science alliance 2025 Sep;8(9)
Life science alliance 2025 Sep;8(9)
Neural and molecular investigation into the paraventricular thalamus for chronic restraint stress induced depressive-like behaviors.
He Y, Ren Y, Chen X, Wang Y, Yu H, Cai J, Wang P, Ren Y, Xie P
Journal of advanced research 2025 Sep;75:521-537
Journal of advanced research 2025 Sep;75:521-537
Knockdown of ACC1 promotes migration and invasion of U251 glioma cells by epigenetically suppressing SDH.
Wei X, Wang Y, Zhao W, Yang W, Tang J, Zhao B, Liu Y
International journal of oncology 2025 Sep;67(3)
International journal of oncology 2025 Sep;67(3)
MAZ Coordinates With HDAC1 to Promote Hepatocarcinoma Proliferation and Metastasis Through Transcriptional Repression of CSK.
Qiu R, Chen W, Zhao S, Zhao H, Qiu T, Hu Q, Xu Z, Zeng L, Kong C, Zhang C, Weng Q, Zhao A, Wang J, He Y, Tu J, Chen M, Zhao Z, Yang Y, Ji J
Molecular carcinogenesis 2025 Sep;64(9):1500-1513
Molecular carcinogenesis 2025 Sep;64(9):1500-1513
The role and mechanism of PGC-1α in oxLDL-induced ferroptosis of vascular endothelial cells.
Li J, He P, Zhang Y, Zhao R, Shen C, Li C, Liu W, Liu Z, Long X, Wang Y, Shi B
Atherosclerosis plus 2025 Sep;61:1-11
Atherosclerosis plus 2025 Sep;61:1-11
Integrated multi‑omics analysis of liver metabolic dysregulation in ACE2 knockout mice.
Xiao S, Guo J, Yu B, Zhao S, Shang Y, Li N, Cui J, Song F, Jiang P
International journal of molecular medicine 2025 Sep;56(3)
International journal of molecular medicine 2025 Sep;56(3)
Nucleotide-binding domain-like receptor protein 3 inflammasome contributes to vascular endothelial barrier dysfunction and shock after burn injury.
Yu H, Lyu F, Cheng Z, Luo M, Sasmita BR, Lan Y, Lv D
Burns : journal of the International Society for Burn Injuries 2025 Sep;51(7):107589
Burns : journal of the International Society for Burn Injuries 2025 Sep;51(7):107589
Activation of Sig-1R by afobazole attenuates Tollip/HMGB1-mediaded CCN2 autophagic degradation and NETs formation in sunitinib-induced cardiotoxicity in mice: Involvement of IRE 1α/ASK1/JNK/ AP-1 trajectory.
Shafik MS, El-Tanbouly DM, Bishr A, Soubh AA, Attia AS, Muhammad RN
Toxicology and applied pharmacology 2025 Sep;502:117423
Toxicology and applied pharmacology 2025 Sep;502:117423
Ginsenoside Rg5 enhances Abemaciclib sensitivity in ER+ breast cancer by modulating cell cycle proteins via transcriptional and post-translational levels.
Chen J, Liao D, Wu C, Liu L, Luo J, Li G, Cao L
Journal of ginseng research 2025 Sep;49(5):594-603
Journal of ginseng research 2025 Sep;49(5):594-603
Introduced paeoniflorin reduces the main toxicity induced by diosbulbin B, the major toxic compound of Dioscorea bulbifera L.: involved inhibiting inflammation and ferroptosis.
Zhang T, Li B, Wang J, Wu X, Song L, Wang Y, Zhang Y, Li Y
Drug and chemical toxicology 2025 Sep;48(5):1080-1089
Drug and chemical toxicology 2025 Sep;48(5):1080-1089
NCOA4 inhibits glioma progression by suppressing the Sonic Hedgehog pathway and its overexpression indicates a better glioma prognosis.
Liu K, Wang H, Qiu T, Wang G, Zhang A, Jia Z, Tong X
Genes & genomics 2025 Sep;47(9):961-972
Genes & genomics 2025 Sep;47(9):961-972
Leukemia Inhibitory Factor via JAK-STAT Signaling Drives Beryllium Sulfate-Induced Epithelial-Mesenchymal Transition in 16HBE Cells.
Li Y, Sun Z, Tong Y, Yan C, Huang L, Zhang Z
Journal of applied toxicology : JAT 2025 Sep;45(9):1720-1729
Journal of applied toxicology : JAT 2025 Sep;45(9):1720-1729
WNK1 Alleviates Chloride Efflux-Induced NLRP3 Inflammasome Activation and Subsequent Neuroinflammation in Early Brain Injury Following Subarachnoid Hemorrhage.
Zhao P, Feng H, Zhou X, Zhou J, Hu F, Hu T, Sun Y
Neuroscience bulletin 2025 Sep;41(9):1570-1588
Neuroscience bulletin 2025 Sep;41(9):1570-1588
Autologous Serum from Sjögren's Syndrome Patients Mitigates Ferroptosis in Hyperosmolarity-Induced Corneal Epitheliopathy.
Chu G, Wang J, Wang Z, Cai X, Shi S, Qing Q, Zhong Y, Zhang Q
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2025 Sep;41(7):397-407
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2025 Sep;41(7):397-407
Endoplasmic Reticulum Stress Inhibition Alleviates Tourniquet-Induced Limb Ischemia-Reperfusion Injury.
Sun Z, Li K, Wang J, Zhao L, Wang H, Wu Q, Ren Z, Guo B, Yu X, Li Y
Journal of biochemical and molecular toxicology 2025 Sep;39(9):e70476
Journal of biochemical and molecular toxicology 2025 Sep;39(9):e70476
Discovery of Baicalein as a Novel Ubiquitin-Specific Protease 21 Inhibitor for the Treatment of Hepatocellular Carcinoma.
Jia H, Zhao Z, Su C, Du J, Yang S, Song J, Han X, Yu F, Sun Z, Chu P
Phytotherapy research : PTR 2025 Sep;39(9):3935-3951
Phytotherapy research : PTR 2025 Sep;39(9):3935-3951
Targeted energy metabolomics analysis-based mitochondrial restoration: Nutritional intervention of dairy-derived MFG-E8 synergistic with egg yolk phosphatidylcholine in skeletal muscle regeneration.
Guan K, Liu X, Liu R, Xiao R, Lu W, Ma Y, Wang R, Niu T
International journal of biological macromolecules 2025 Sep;323(Pt 2):147215
International journal of biological macromolecules 2025 Sep;323(Pt 2):147215
EgG1Y162 protein from Echinococcus granulosus modulates the immune functions of mouse splenic lymphocytes and regulates Th9 cells.
Chen X, Zhao H, Tuohetali A, Aizezi M, Song Y, Zhang X, Zhu J, Zhou T, Chen G, Lin R, Aimulajiang K
International journal of biological macromolecules 2025 Sep;322(Pt 1):146515
International journal of biological macromolecules 2025 Sep;322(Pt 1):146515
PD-L1/PD-1 checkpoint pathway regulates astrocyte morphogenesis and myelination during brain development.
Wang Y, Zhang M, Zhang T, Zhang S, Ji F, Qin J, Li H, Jiao J
Molecular psychiatry 2025 Sep;30(9):3895-3911
Molecular psychiatry 2025 Sep;30(9):3895-3911
circEFR3A promotes breast cancer progression by sponging miR-590-3p to upregulate androgen receptor expression.
Mi Y, Wang X, Song H, Wu Z, Li S, Liu F, Liu W, Sang M, Geng C
Oncology letters 2025 Sep;30(3):446
Oncology letters 2025 Sep;30(3):446
Puerarin Attenuates Osteoarthritis via Multi-Target Regulation of Inflammation, Apoptosis, and ECM Degradation.
Zhang Y, Chen Z, Cheng Y, Zhou Y, Yang Y, Che M, Zhang Y, Li Y
Journal of cellular and molecular medicine 2025 Sep;29(18):e70833
Journal of cellular and molecular medicine 2025 Sep;29(18):e70833
The m6A transferase METTL3 regulates high glucose-induced proliferation and apoptosis of human lens epithelial cells through the lncRNA TUG1/KHSRP/p38MAPK signaling axis.
Li Y, Yao Z, Gao X, Niu Y, Gao Z, Jiang S
Experimental eye research 2025 Sep;258:110492
Experimental eye research 2025 Sep;258:110492
Benserazide‑mediated targeting hexokinase 2 enhances the cytotoxicity of cisplatin in non-small cell lung cancer cell models.
Wang K, Wang S, Shan W, Huang S, Fang T, Zhou Y, Liu L, Sha O, Tam KY
Biochemical pharmacology 2025 Sep;239:117071
Biochemical pharmacology 2025 Sep;239:117071
Cuproptosis involvement in neonatal ischemic-hypoxic encephalopathy through the COMMD1/ATP7A signaling axis.
Luo J, Zhang X, Bharati L, Hua Z, Chen S, Dong Z
Biochemical pharmacology 2025 Sep;239:117054
Biochemical pharmacology 2025 Sep;239:117054
Mito-tempo ameliorates tubular injury of diabetic nephropathy via inhibiting mt-dsRNA release and PKR/eIF2α pathway activation.
Duan T, Sun L, Xi Y, Li C, Zhao Q, Xu L, Yang M, Liu C, Xiao L, Deng T, Sun L
Free radical biology & medicine 2025 Sep;237:147-159
Free radical biology & medicine 2025 Sep;237:147-159
Active compounds of licorice ameliorate microplastics-induced intestinal damage by targeting FADD.
Xue W, Fan X, Hui Y, Yu J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Sep;203:115570
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Sep;203:115570
Chlorogenic acid counteracts mycophenolate mofetil-induced neurotoxicity in zebrafish and PC12 cells: A potential bioremediation strategy for aquatic pharmaceuticals.
Wu J, Guo JJ, Tong FC, Zhang SL, Zhang JL, Chen MY, Yu HC
Environment international 2025 Sep;203:109771
Environment international 2025 Sep;203:109771
Bioactive ROS-responsive nanotherapeutics attenuate intermittent hypoxia-induced cognitive impairment via NRF2/KEAP1/HO-1 signaling.
Huang Y, Xie H, Liu L, Zhao H, Li B, Zhang F
Neurochemistry international 2025 Sep;188:105997
Neurochemistry international 2025 Sep;188:105997
Phytochemistry analysis of the above-ground parts of Sanguisorba officinalis L. and its effects on myocardial cell metabolism.
Zhang B, Zhang Q, Liu Z, Zhai Y, Jin P, Luan H
Fitoterapia 2025 Sep;185:106686
Fitoterapia 2025 Sep;185:106686
Association of elevated ACSL4 expression with impaired endometrial receptivity in endometriosis and restoration by ACSL4 inhibitor PRGL493.
Xu L, Wei H, Shang Y, Yang Q
Journal of reproductive immunology 2025 Sep;171:104630
Journal of reproductive immunology 2025 Sep;171:104630
Optimized synthesis of 5N-D and the exploration of its role as a promising anti-aging agent via AKR1B1 inhibition and PI3K/Akt/Nrf2 regulation.
Liu L, Wang C, Chen Z, Yin M, Zhang K, Zhang C, Peng S, Li M, Jiang S, Chen H
Bioorganic chemistry 2025 Sep;164:108886
Bioorganic chemistry 2025 Sep;164:108886
Design, synthesis and anti-gastric cancer activity of stable Bisamide curcumin analogues.
Wu J, Wang B, Gan X, Wu Y, Wu Y, Liu X, Hu R, Xie L, Bai H, Jin M, Fang B, Khushafah F, Wei T, Li W
Bioorganic chemistry 2025 Sep;164:108793
Bioorganic chemistry 2025 Sep;164:108793
DDIT4 knockdown suppresses venous malformation progression by inhibiting NF-κB signaling as a potential therapeutic target.
He Y, Lin J, Li Y, Cheng X, Wang T, Wang W, Zeng W, Li Y
Microvascular research 2025 Sep;161:104833
Microvascular research 2025 Sep;161:104833
Tectorigenin attenuates myocardial damage by doxorubicin-induced ferroptosis by activating the p62-Keap1-Nrf2/HO-1/GPX4 axis.
Xie L, Xiao S, Zhou Q, Chen W, Hu Z, Li Y, Liu Y, Ma X, Li Y
Journal of traditional and complementary medicine 2025 Sep;15(5):573-581
Journal of traditional and complementary medicine 2025 Sep;15(5):573-581
Brusatol ameliorates irinotecan-induced delayed diarrhea via inhibition of the cGAS-STING pathway and modulation of intestinal flora.
Lai Z, Zhang Y, Huang W, Wang J, Liu C, Ren M, Huang X, Chen J, Xie J, Chen B, Lai Z, Xie Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157071
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157071
Shenling Tongqiao powder targets TGF-β1/Smad-Wnt/β-catenin axis to suppress epithelial-mesenchymal transition in chronic rhinosinusitis.
Liu K, Zeng H, Zhu X, Deng H, Deng W, Li S, Zhu Y, Bin J, Lu S, Wu W, Wu Q, Liao J, Hu G, Chang W, Ying Y, Wang Y, Zhu Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157065
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157065
Alpha-Heredin targets CAMKⅡ/DRP1-Mediated mitochondrial fission to trigger ferroptosis in pancreatic ductal adenocarcinoma.
Li X, Si W, Zhang Y, Yang P, Ruan L, Ba H, Chen Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157048
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157048
Breviscapine injection and its main component scutellarin prevents lethal enterovirus infection by inhibiting neuroinflammation and oxidative stress in newborn mice.
Yang W, Wang J, Tao Y, Li X, Tao S, Zhu H, Chen X, Shan J, Li Y, Ma T, Cao P, Cui G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157042
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157042
Dihydrotanshinone I inhibits ovarian tumor growth by suppressing ITGB1/FAK-mediated extracellular matrix signaling.
Han B, Sun C, Yang R, Li X, Kang J, Cai J, Zhou S, Wang G, Wang J, Zhang J, Sun Y, Kai G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157023
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157023
Rhizoma Panacis Majoris ameliorates rheumatoid arthritis by restoring apoptosis and autophagy dysregulation through reducing HMGB1 expression.
Pang X, Song R, Li Z, Shi X, Zhang Z, Liu Y, Xu H, Song Z, Zhou R, Tang Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:156943
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:156943
Lactate induces oxidative phosphorylation in osteoblasts via Gpr81-Stat3 signaling.
Hu X, Shen J, Wang R, Han C, Shi X, Hu J, Zhang M, Wang P, Zhang X, Wu Y
Cellular signalling 2025 Sep;133:111877
Cellular signalling 2025 Sep;133:111877
Identification of ferroptosis-related genes in periodontitis through bioinformatics analysis and experimental validation.
Zhou K, Chen H, Dong J, Song Z, Sun M
Journal of stomatology, oral and maxillofacial surgery 2025 Sep;126(4S):102291
Journal of stomatology, oral and maxillofacial surgery 2025 Sep;126(4S):102291
Coactosin-Like Protein Reduces Prostaglandin D(2) Production in Alveolar Macrophages and Alleviates Allergic Airway Inflammation.
Pan LL, Ren Z, Li B, Liang W, Luo Y, Yang Q, Liu H, Dong X, Tian H, Zou H, Samuelsson B, Rådmark O, Sun J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(34):e01673
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(34):e01673
Duck plague virus UL13 hijacks an RNA-binding protein, interferon induced protein with tetratricopeptide repeats 5, to promote replication.
Zhou L, Hao Y, Cheng A, Zhang W, Wang M
International journal of biological macromolecules 2025 Sep 9;328(Pt 1):147576
International journal of biological macromolecules 2025 Sep 9;328(Pt 1):147576
Exploring testosterone's impact on pulmonary health in a rat model of COPD: Investigating MMP-9 and FGF-23.
Ji Z, Zhang C, Wang B, Zhao J
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2025 Sep 9;:10815589251378184
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2025 Sep 9;:10815589251378184
A TP53 Intron-Derived Peptide Promotes Tumor Survival.
Cadena LA, Luo KL, Otero-Perez CA, Fernandez SM, Huang YW, Zhao R, Lee DF, Ting AH, Ye F, You MJ, Lee SH
bioRxiv : the preprint server for biology 2025 Sep 9;
bioRxiv : the preprint server for biology 2025 Sep 9;
Hsp60 lactylation promotes mitochondrial dysfunction and trophoblast apoptosis in preeclampsia.
Xu J, Wang X, Qin Z, Liu J, Chen J, Li Q, Wang X, Zhuang L
Biochemical and biophysical research communications 2025 Sep 8;778:152379
Biochemical and biophysical research communications 2025 Sep 8;778:152379
Study on the role of FN1 in chronic obstructive pulmonary disease.
Wang F, Zhang J, Yuan Y, Zhou J, Pang S, Li X, Qiu A
Gene 2025 Sep 5;963:149551
Gene 2025 Sep 5;963:149551
α-Cyperone safeguards against cerebral ischaemia‒reperfusion injury through the activation of the Nrf2 signalling pathway.
Yu H, Chen Y, Qu T, Hang J, Huang X, Hu A, Wang T, Gao Y, Shao J, Li Y, Chen Y
European journal of pharmacology 2025 Sep 5;1002:177842
European journal of pharmacology 2025 Sep 5;1002:177842
Timosaponin A3 Ameliorates Prostate Cancer Progression via Upregulating STARD4 Mediated Cholesterol Metabolism.
Zhi Y, Ge L, Wang S, Zang W, Zhang Z, Xu T, Zhang Y, Song F, Huang P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 30;39(18):e71063
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 30;39(18):e71063
Natural Polyphenol Pentagalloyl Glucose as a Potent Xanthine Oxidase Inhibitor for Hyperuricemia Treatment.
Du J, Liu Y, Li L, Yin Q, Yu D, He P, Wang N, Yuan R, Yin Z, Tu Y, Li Y
Journal of agricultural and food chemistry 2025 Sep 3;73(35):21889-21904
Journal of agricultural and food chemistry 2025 Sep 3;73(35):21889-21904
Isoacteoside alleviates LPS-induced depressive-like behaviors in mice by inhibiting neuroinflammation through regulating microglial polarization and oxidative stress.
Bi J, Zhang H, Wei J, Huang X, Dong Y, Dong Y, Xie Y, Li R, Chen S, Zhao Z, Cheng B
Behavioral and brain functions : BBF 2025 Sep 29;21(1):30
Behavioral and brain functions : BBF 2025 Sep 29;21(1):30
Yak milk ameliorates chronic alcohol-induced brain injury in mice by modulating the gut microbiota and suppressing the TLR4/NF-κB pathway.
Liang Z, Liu Q, Wang M, Gong D, Qin M, Li H, Huang X, Wang Y, Long D
Food & function 2025 Sep 29;16(19):7880-7899
Food & function 2025 Sep 29;16(19):7880-7899
S-ketamine relieves neuropathic pain by inhibiting microglia phagocytosis of the perineuronal nets.
Yang X, Wang Y, Jiang L, Huang S, Jiao Y, Wu Q, Zhang Y, Huang Y, Gu X, Xu R, Zhang W, Ma Z
Scientific reports 2025 Sep 29;15(1):33596
Scientific reports 2025 Sep 29;15(1):33596
Salecan Suppresses Pancreatic Cancer Progression by Promoting Necroptosis via the RIPK1/MLKL Pathway.
Du W, Xu R, Chen P, Wen J, Sun L, Chen X
Nutrients 2025 Sep 28;17(19)
Nutrients 2025 Sep 28;17(19)
Comparison of Quercetin and Isoquercitrin's Anti-Heart Failure Activity via MAPK Inflammatory Pathway and Caspase Apoptosis Pathway.
Guo A, Chen X, Bai Y, Dai Y, Yue H
Pharmaceuticals (Basel, Switzerland) 2025 Sep 26;18(10)
Pharmaceuticals (Basel, Switzerland) 2025 Sep 26;18(10)
Overexpression of alcohol dehydrogenase 1 A inhibits the progress of triple negative breast cancer via Wnt/β-catenin signaling.
Su L, Qiao C, Luo J, Zhu B, Liu Y
Scientific reports 2025 Sep 26;15(1):32986
Scientific reports 2025 Sep 26;15(1):32986
Resveratrol Alleviated Oxidative Damage of Bovine Mammary Epithelial Cells via Activating SIRT5-IDH2 Axis.
Yang H, Liu L, Zhang X, Gao S, Li A, Dong J, Lu G, Yang Q, Liu X, Sun S, Li H, Liu Y, Wang Y, Han Y
Antioxidants (Basel, Switzerland) 2025 Sep 26;14(10)
Antioxidants (Basel, Switzerland) 2025 Sep 26;14(10)
The synergistic administration of sanguinarine and curcumin ameliorates indomethacin-induced small intestinal injury in rats through the modulation of Nrf2 and NF-κB signaling pathways.
Lin X, Zhou Y, Xia L, Chen M, Liao W, Yang X, Tuo Q, Lin L, Liao D, Zeng J
Biochemical and biophysical research communications 2025 Sep 25;781:152551
Biochemical and biophysical research communications 2025 Sep 25;781:152551
NIR-II Light-Controlled Photosynthetic Activation via an Upconversion Nanoplatform for Targeted Bioenergetic Therapy in Acute Kidney Injury.
Hu X, Cheng X, Shao L, Yang L, Chen G, Yan Z, Yu M, Kang Y, Mou X, Yang X, Cai Y
Journal of medicinal chemistry 2025 Sep 25;68(18):19746-19766
Journal of medicinal chemistry 2025 Sep 25;68(18):19746-19766
An integrated research strategy based on "compound exogenous chemical substances-endogenous metabolites in disease": To explore the scientific basis of Modified Bazhen Yimu Gao in the treatment of primary dysmenorrhea.
Wang S, Wang Y, Wang Y, Li T, Yang X, Bao Y, Meng X
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120481
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120481
Mechanism of xihuang pill inhibition of SLC7A11 deubiquitination through downregulation of the OTUB1 to promote ferroptosis in triple-negative breast cancer.
Qiu Y, Zhang G, Su R, Chen Y, Yi C, Zhan S, Zhang H, Liu T, Li J, Wu Y, Yan X, Ma M
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120456
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120456
Ginsenoside Rh2 ameliorates pulmonary fibrosis via HSP70-dependent autophagic flux regulation and senescence arrest.
Zhang WX, Li K, Li WL, Wang JQ, Gao XF, Zhang S, Zhang M, Jiang S, Li W
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120448
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120448
Danggui Buxue Decoction inhibits pulmonary fibrosis by alleviating TGF-β1-induced proliferation and apoptosis in EBL cells via PI3K/AKT/FOXO1 pathway.
Yang Z, Ji P, Zhang W, Li C, Wu F, Hua Y, Wei Y, Cao Y
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120384
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120384
Xuebijing alleviates sepsis-induced acute lung injury by inhibiting alveolar epithelial cell apoptosis via cAMP/PKA signaling pathway.
Ren T, Chen Q, Xu J, Jiang H, Guo T, Wu Y, Xu Y, Dai L
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120370
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120370
Integration of network pharmacology and transcriptomics to reveal the mechanism of Paeoniae Radix Alba Polysaccharide in alleviating hepatic fibrosis.
Fan X, Gao J, Liu S, Hua J, Shao D, Jia L, Shen Y, Wang Z, Jin Z, Wang J
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120357
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120357
Enzyme kinetic and in silico characterization of cytochrome P450 2E1 inhibition by hydro-ethanolic extract of Entada africana and its protective role in acetaminophen-induced hepatotoxicity.
Kouam AF, Zemnou CT, Ngounou E, Somene FSD, Zeuko'o EM, Ofon AE, Njayou FN, Moundipa PF
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120315
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120315
Protective effect and mechanism of Zhuang medicine Tinosporae Radix on LPS-induced neuroinflammation.
Wang J, Xie Y, Wang S, Chen L, Wu L, Hu Z, Deng J, Wu Z, Wang Y, Wang S, Huang L
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120276
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120276
α-lipoic acid attenuates duodenal non-heme iron absorption via microRNA-mediated regulation of divalent metal transporter 1 in iron overloaded rats.
Jiang S, Shu Y, Guo S, Ni Y, Shan H, Ma W
Molecular biology reports 2025 Sep 24;52(1):946
Molecular biology reports 2025 Sep 24;52(1):946
Mechanism of Piezo1 regulating chondrocyte mitochondrial function and promoting fracture healing through β-catenin/LARS2 signaling pathway.
Zhang T, Lv H, Jia S, Wang L, Liu W, Ding K, Du X, Hou G, Hou Z, Zhang Y, Zou W, Chen W, Zhu Y
Bone research 2025 Sep 24;13(1):79
Bone research 2025 Sep 24;13(1):79
GP2a I118 and GP4 D43 play critical roles in the attachment of PRRSV to the CD163 receptor: implications for anti-PRRSV infection targets.
Liu G, Huang X, Yang Y, Chen M, Tian X, Song H, Wang H, Wang S, Wang H, Cai X, An T
Journal of virology 2025 Sep 23;99(9):e0096325
Journal of virology 2025 Sep 23;99(9):e0096325
Inhalation of Mesenchymal-Stem-Cell-Derived Nanovesicles Delivering Catalase Enhances the Treatment for Acute Lung Injury.
Zhang L, Yan X, Li X, Huang Y, Wang X, Lin J, Zhang H, Liu Z, Guo Q
ACS nano 2025 Sep 23;19(37):33184-33201
ACS nano 2025 Sep 23;19(37):33184-33201
YTHDF1-mediated mitochondrial dysfunction and allergic airway inflammation by interaction with β-catenin/TCF4 signaling.
Xie C, Huang J, Chen Y, Huang B, Chen Y, Li Y, Gong Z, Ma Y, Xu M, Fan K, Hu D, Zhao X, Huang P, Peng X, Cai S, Zhao W, Zhao H
International immunopharmacology 2025 Sep 23;162:115181
International immunopharmacology 2025 Sep 23;162:115181
Network pharmacology analysis and experimental validation of EGCG's therapeutic effects against acute lung injury in sepsis.
Jin X, Weng Q, Qian K, Liu F
International immunopharmacology 2025 Sep 23;162:115175
International immunopharmacology 2025 Sep 23;162:115175
Elevated ESM1 facilitates peripheral nerve regeneration via enhancing Schwann cell activity and developing a pro-regenerative microenvironment.
Ren Z, Miao Y, Zhang Y, Zhao L
Experimental neurology 2025 Sep 22;395:115476
Experimental neurology 2025 Sep 22;395:115476
Cardiomyocyte pyroptosis inhibited by dental pulp-derived mesenchymal stem cells via the miR-19a-3p/IRF-8/MAPK pathway in ischemia-reperfusion.
Li Y, Wang X, Weng S, Xia C, Meng X, Yang C, Guo Y, Pei Z, Gao H, Wang F
Chinese medical journal 2025 Sep 20;138(18):2336-2346
Chinese medical journal 2025 Sep 20;138(18):2336-2346
BACH1 recruits STAT3 to enhance leukemia inhibitory factor receptor activity and augments the self-renewal capacity of mouse embryonic stem cells.
Ma J, Ma S, Niu C, Wang S, Wei X, Meng D, Zhi X, Guo J
Stem cell research & therapy 2025 Sep 2;16(1):483
Stem cell research & therapy 2025 Sep 2;16(1):483
A novel chronic hepatitis B mouse model with immune activation and liver fibrosis.
Wu D, Liu Z, Song Z, Yu L, Guan Z, Liu H, Zhao J, Jin Z, He X, Zhang Y, Cao L, Dai G, Huang J, Kang Q
Microbiology spectrum 2025 Sep 2;13(9):e0251324
Microbiology spectrum 2025 Sep 2;13(9):e0251324
FGL2-induced metabolic dysregulation in enteric neural crest cells provides insight into Hirschsprung disease pathogenesis.
Han J, Liu X, Wang Y, Xu Q, Sun D, Zhang X, He X, Ma C, Ren X, Wang J, Mou Y, Zhang Q, Wang D, Mu W, Hou P, Li A
iScience 2025 Sep 19;28(9):113423
iScience 2025 Sep 19;28(9):113423
Integrative multi-omics analysis decodes HOXC9-driven malignant transformation and metastasis in OSCC.
Xu M, Sun Z, Wang D, Li G, Feng W, Qiao C, Shi C, Liu Q, Chen P, An Z
iScience 2025 Sep 19;28(9):112919
iScience 2025 Sep 19;28(9):112919
Novel pH-Responsive PSS-Loaded Chitosan Matrix Nanoparticles Ameliorate Pressure Overload-Induced Cardiac Hypertrophy.
Xu M, Fan Z, Wang D, Li D, Zou H, Xue Y, Wang S, Li C
Marine drugs 2025 Sep 19;23(9)
Marine drugs 2025 Sep 19;23(9)
Cu-Mn Bimetallic Mesoporous Silica Nanosonosensitizers Enable Oxeiptosis-Mediated Sonodynamic Therapy for Ultra-Minimally Invasive Treatment of Benign Prostatic Hyperplasia.
Chang M, Lv J, Sun L, Chen A, Zhang F, Fan G, Liu Z, Li J, Shen H, Shi M, Niu Y, Tian Y, Liu X, Yang B
ACS applied materials & interfaces 2025 Sep 17;17(37):51820-51839
ACS applied materials & interfaces 2025 Sep 17;17(37):51820-51839
Dynamic negative pressure enhances MSC-derived exosomes treatment for vessel injury-related erectile dysfunction by facilitating cavernous diffusion.
Feng C, Li R, Wang G, Liu S, Fu Q
International journal of pharmaceutics 2025 Sep 15;682:125999
International journal of pharmaceutics 2025 Sep 15;682:125999
Gremlin 1 regulates granulosa cell apoptosis through the TGF-β/SMAD signaling pathway during bovine follicular atresia.
Xu Y, Liu M, Yang T, Zhao B, Li Y, Wang J, Wang Y, Lin P, Chen H, Wang A, Jin Y, Tang K
Molecular and cellular endocrinology 2025 Sep 15;607:112605
Molecular and cellular endocrinology 2025 Sep 15;607:112605
Excessive mitochondrial stress response triggers neuronal injury through the persistent eIF2α phosphorylation in mice exposed to manganese.
Jia Y, He B, Chen K, Liu K, Yu C, Sun B, Ma Z, Xu B
Journal of hazardous materials 2025 Sep 15;496:139407
Journal of hazardous materials 2025 Sep 15;496:139407
Enhanced bioactivity of honeysuckle-Cassia seeds extracts through Lactobacillus acidophilus and Bacillus subtilis co-fermentation: Impact on alcoholic liver disease and gut microbiota.
Zhou M, Zhang Y, Song Z, Tang S, Liu Z, Pang M, Zhang D, Wu X, Yu X, Wang P, Wei Y
Food chemistry 2025 Sep 15;486:144463
Food chemistry 2025 Sep 15;486:144463
Region-Specific Metabolic Alterations in the Tryptophan Pathway in Cisplatin-Induced Acute Kidney Injury.
Feng Y, Zhang Y, Li J, Yu J, Tian Y, Zhang Z, Xu F, Zhang P
Chemical research in toxicology 2025 Sep 15;38(9):1472-1484
Chemical research in toxicology 2025 Sep 15;38(9):1472-1484
Blue light induces corneal epithelial damage by activating the NLRP3 inflammasome pathway.
Ge J, Yang Q, Yu X, Xia Y, Zhang X, Zhang L, Li Y, Wang Y, Shen C, Li X, Song D, Chen Z, Chen K, Li X, Shen Y, Tong J
Ecotoxicology and environmental safety 2025 Sep 15;303:118921
Ecotoxicology and environmental safety 2025 Sep 15;303:118921
Protective effects of total flavonoids of Astragalus membranaceus Bunge combined with selenium-enriched yeast against zearalenone-induced reproductive injury in male mice.
Wang W, Ge BJ, Sang R, Liu XM, Yu T, Zhang XM
Ecotoxicology and environmental safety 2025 Sep 15;303:118798
Ecotoxicology and environmental safety 2025 Sep 15;303:118798
Exploring the potential mechanisms of Jinglinzi powder in treating hepatocellular carcinoma based on LC-MS, network pharmacology, molecular docking, and experimental validation.
Liu G, Kuang S, Zhong W, Yang A, Huang X, Xie Y, Zhang X, Li Y, Qin Q, Liu G
Journal of pharmaceutical and biomedical analysis 2025 Sep 15;263:116899
Journal of pharmaceutical and biomedical analysis 2025 Sep 15;263:116899
Unraveling Laser-Induced peripheral Pain: Proteomic profiling and electrophysiological Dynamics in mice.
Guo Y, Ren X, Li H, Tian R, Xu S, Cao Z, Gu X, Shang M, Wang H, Xing J
Brain research 2025 Sep 15;1863:149743
Brain research 2025 Sep 15;1863:149743
The Outer Membrane Protein Tp92 of Treponema pallidum Induces BeWo Cells Apoptosis and Oxidative Stress via the Nrf2/keap1 Pathway.
Huang S, Zhao Y, Xiong S, Liu Z, Ding X, Yao J, Lin T, Yu H, Zhang X, Zhao F
ACS infectious diseases 2025 Sep 12;11(9):2500-2514
ACS infectious diseases 2025 Sep 12;11(9):2500-2514
Novel Indoline Derivatives as Ferroptosis Inhibitors: Synthesis, Biological Evaluation, and Mechanistic Investigation.
Shao W, Liu Y, Jiang D, Xing Z, Qiao J, Liu M, Huang X, Zhang R, Fang Y, Peng W
ChemMedChem 2025 Sep 11;20(17):e202500487
ChemMedChem 2025 Sep 11;20(17):e202500487
Light-Activated CD36-Targeted Cuproptosis Triggers Metabolic-Immune Synergy for Precision Breast Cancer Therapy.
Wang S, Shen Y, Hu B, Wu Q, Wang N, Wang Z, Zhang Z, Li Y, Jiang J
ACS applied materials & interfaces 2025 Sep 10;17(36):50317-50336
ACS applied materials & interfaces 2025 Sep 10;17(36):50317-50336
DAZAP2 functions as a pan-coronavirus restriction factor by inhibiting viral entry and genomic replication.
Feng F, Chen J, Li R, Zhu Y, Ma Y, Wang Z, Wang Y, Gao Z, Yang L, Yu Y, Liu Y, Sun Y, Liao Y, Huang X, Zhang Q, Huang Y, Qiu L, Wu J, Zhao J, Liu C, Ding Q, Xie Y, Yuan Z, Hong Y, Zhang P, Sun J, Zhao J, Zhang R
mBio 2025 Sep 10;16(9):e0038525
mBio 2025 Sep 10;16(9):e0038525
SLC25A40 promotes NSCLC growth by enhancing NADPH-mediated lipid synthesis and suppressing ROS accumulation-induced ferroptosis.
Xue P, Guo X, Zhang B, Yang X, Gao J, Zhou F, Ma J, Jin F
Experimental cell research 2025 Sep 1;452(1):114727
Experimental cell research 2025 Sep 1;452(1):114727
Polyethylene terephthalate (PET) microplastics induced male reproductive toxicity in mice by activating the p38-MAPK pathway.
Zhang X, Ma T, Sun J, Fang Y, Wang Y, Li X, Zhao Z, Su N, Liu M, Bai J, Liu J, Wu J
Ecotoxicology and environmental safety 2025 Sep 1;302:118756
Ecotoxicology and environmental safety 2025 Sep 1;302:118756
Gestational zearalenone causes fetal intrauterine growth restriction partially through deriving ROS-Drp1 mediated placental PANoptosis.
Liu JR, Wu FN, Lin S, Chen C, Liu Y, Fan JW, Hong Q, Chen YH
Ecotoxicology and environmental safety 2025 Sep 1;302:118636
Ecotoxicology and environmental safety 2025 Sep 1;302:118636
YAP/Nrf2 suppresses ferroptosis to alleviate acute lung injury induced by intestinal ischemia/reperfusion.
Tang L, Yang C, Peng Y, Liu M, Wei N, Fan X, Yang B, Jia J, Chen Y, Feng J, Zhou J
Redox biology 2025 Oct;86:103811
Redox biology 2025 Oct;86:103811
Arylsulfatase K attenuates airway epithelial cell senescence in COPD by regulating parkin-mediated mitophagy.
Yang R, Zhan Y, Deng Z, Zhang J, Chen S, Zhang Y, Fu H, Meng X, Wu J, Gu Y, Huang Q, Wang C, Xie J
Redox biology 2025 Oct;86:103793
Redox biology 2025 Oct;86:103793
MicroRNA-130 as a critical modulator of cardiac remodeling: interplay between autophagic flux and ferroptotic pathways in acute myocardial infarction.
Chen L, Jiang D, Kou W, Xu Y
Molecular and cellular probes 2025 Oct;83:102037
Molecular and cellular probes 2025 Oct;83:102037
Transplanting neural stem cells overexpressing miRNA-21 can promote neural recovery after cerebral hemorrhage through the SOX2/LIN28-let-7 signaling pathway.
Dai W, Li Y, Du J, Shen G, Fan M, Su Z, Xu F, Yuan F
Animal models and experimental medicine 2025 Oct;8(10):1760-1774
Animal models and experimental medicine 2025 Oct;8(10):1760-1774
Multilevel Analysis Reveals the Critical Role of Cell Death-Related Molecules and Drugs in Temporomandibular Disorders.
Zhang Y, Liao X, Zhang D, Xu Q, Bu L, Shen P, Zheng J, Yang C
International dental journal 2025 Oct;75(5):100934
International dental journal 2025 Oct;75(5):100934
Liver sinusoidal endothelial cells secret C-X-C motif chemokine ligand 10 to promote the recruitment of invariant NKT cells in acetaminophen-induced liver injury.
Wang F, Zhang S, Yao Y, Yu P, Xue K, Xu X, Li G, Zhou H
Science China. Life sciences 2025 Oct;68(10):2982-2994
Science China. Life sciences 2025 Oct;68(10):2982-2994
Neuroprotective Effect of Salvianolic Acid C in Neonatal Rats Following Hypoxic-ischemic Brain Damage.
Dai C, Li X, Dong Z, Xu B, Lai X, Wei J, Long D, Hu D
Molecular neurobiology 2025 Oct;62(10):13363-13378
Molecular neurobiology 2025 Oct;62(10):13363-13378
Knockdown of the CALHM1 Gene Alleviates Allodynia in Rats With Trigeminal Neuralgia.
Zhu X, Yi Z, Li X, Duan K, Huang D, Yan X
Journal of oral rehabilitation 2025 Oct;52(10):1707-1714
Journal of oral rehabilitation 2025 Oct;52(10):1707-1714
Magnesium ions attenuate tendon graft fibrosis during its ligamentization after ACL reconstruction through modulation of fibroblast to myofibroblast trans-differentiation by promoting PGE2 secretion.
Xu C, Luo Y, Cai Z, Ji J, Guo Z, Cai Z, You C, Zhou Y, Chen Z, Zhang W, Gong N, Wang J
Bioactive materials 2025 Oct;52:474-491
Bioactive materials 2025 Oct;52:474-491
Baicalin inhibits LPS-induced apoptosis and inflammation in WI- 38 cells by promoting FOXA2/TRIM27 Interaction: Implications for pediatric pneumonia mechanisms.
Gao L, Zeng X, Huang Y, Huang L
Naunyn-Schmiedeberg's archives of pharmacology 2025 Oct;398(10):14131-14142
Naunyn-Schmiedeberg's archives of pharmacology 2025 Oct;398(10):14131-14142
Diweng Zhixie Power Ameliorates Dampness-Heat Diarrhea by Restoring Intestinal Microbiota Dysbiosis and Short-Chain Fatty Acids.
Song X, Mi WW, Zhang H, Ji P, Yao WL, Wei YM, Hua YL
Biomedical chromatography : BMC 2025 Oct;39(10):e70210
Biomedical chromatography : BMC 2025 Oct;39(10):e70210
On-Demand ER Stress Modulation in Tumor Cells and TAMs via an Adaptively Transformable Nanoplatform Enhances Photodynamic Immunotherapy.
Zhao B, Chen X, Xu S, Xing Y, Shao J, Xiao Y, Qi J, Qian H, Huang D, Chen W, Zhong Y
Advanced materials (Deerfield Beach, Fla.) 2025 Oct;37(42):e07299
Advanced materials (Deerfield Beach, Fla.) 2025 Oct;37(42):e07299
Single amino acid substitution at position 614 in SARS-CoV-2 Spike Protein alters viral assembly and infectivity.
Shi X, Wang J, Li C, Du S
Virus research 2025 Oct;360:199624
Virus research 2025 Oct;360:199624
Dual-Functional Silicon-Based Nanofluorescent Platform for Iron Detection and Capecitabine Delivery in Colorectal Cancer Treatment.
Fang X, Wang T, Zhang Y, Song J
Journal of fluorescence 2025 Oct;35(10):9559-9571
Journal of fluorescence 2025 Oct;35(10):9559-9571
3D printing-biomimetic local stiff niche enhances glycolysis to boost PDAC cell stem-like phenotype via N6-methyladenosine-suppressed YAP1 mRNA decay.
Wu D, Guan X, Yang T, Yan J, Zhu B, Zhou J, Guo Y, Lu Y
Materials today. Bio 2025 Oct;34:102176
Materials today. Bio 2025 Oct;34:102176
Role of cellular prion protein in mouse granulosa cells and its effects on ovarian function in knockout mice.
Cao Q, Wang H, Hu J, Wang Y, Dai T, Liu F, Yang X, Yang Q, Tu C
Molecular medicine reports 2025 Oct;32(4)
Molecular medicine reports 2025 Oct;32(4)
Vitamin C reduces the loss of retinal ganglion cells in chronic glaucoma by inhibiting neuroinflammation.
Mou Z, Zheng Y, Wang X, Tan S, Yuan J, Li H
Nutritional neuroscience 2025 Oct;28(10):1315-1333
Nutritional neuroscience 2025 Oct;28(10):1315-1333
METTL1 drives glioma progression by promoting N7-methylguanosine (m7G) modification of glycolysis-related enzyme PGK1.
Fan B, Wang Y, Qin X, Yan Z, Du W
Pathology, research and practice 2025 Oct;274:156174
Pathology, research and practice 2025 Oct;274:156174
USP32 stabilizes SEMA4C to promote malignant behavior of colon cancer cells.
Huang S, Cai Z, Wang Y, Zheng W, Zhan S, Huang M, Chen J
Pathology, research and practice 2025 Oct;274:156162
Pathology, research and practice 2025 Oct;274:156162
Magnoflorine ameliorates cartilage degradation in osteoarthritis through inhibition of mitochondrial reactive oxygen species-mediated activation of the NLRP3 inflammasome.
Peng Y, Huang YH, Luo X, Li MC, Xiao QQ, Qiu L, Fu Q
Journal of Asian natural products research 2025 Oct;27(10):1528-1549
Journal of Asian natural products research 2025 Oct;27(10):1528-1549
Impact of tertiary lymphoid structure scores and their stage of maturation on prognosis of colorectal cancer patients.
Shen S, Sun R, Wang T, Zhang D, Che N, Wang X, Zhao N
Genes and immunity 2025 Oct;26(5):449-461
Genes and immunity 2025 Oct;26(5):449-461
Synergistic anti-tumor effects of mRNA vaccine and PERK inhibitor combination in melanoma treatment.
Li X, Ma L, Guo J, Wei Y, Ma S, Mai Y, Gou G, Zuo W, Yang J
Colloids and surfaces. B, Biointerfaces 2025 Oct;254:114808
Colloids and surfaces. B, Biointerfaces 2025 Oct;254:114808
Increased urea nitrogen salvaging by a remodeled gut microbiota helps nonhibernating pikas maintain protein homeostasis during winter.
Shi F, Zou D, Zhang L, Guo N, Yu J, Degen AA, Tang X, Ren S, Ru Y, Zheng S, Zhang Y, Wang D
PLoS biology 2025 Oct;23(10):e3003436
PLoS biology 2025 Oct;23(10):e3003436
Glia maturation factor-β deficiency improves insulin resistance by promoting CARM1-mediated lipid turnover.
Xu J, Zhu L, Li J, Xu J, Cui T, Jia S, Zhu T, Shi S, Gao F, Jin C, Tian H, Wang J, Ou Q, Xu JY, Bi YL, Xu GT, Zhang X, Lu L
Pharmacological research 2025 Oct;220:107937
Pharmacological research 2025 Oct;220:107937
Profibrotic impact of PAD4-driven macrophage extracellular traps in ulcerative colitis.
Wang Z, Shi R, Shi Y, Sun T, Shen Y, Wu C, Yang Y, Fan H, Wu J
Pharmacological research 2025 Oct;220:107933
Pharmacological research 2025 Oct;220:107933
miR-204-5p Mitigates Disc Degeneration via SKI-Mediated Modulation of Apoptotic Signaling and Matrix Remodeling in Nucleus Pulposus.
Ran R, Gong CY, Wu ZL, Zhang SB, Zhang K, Zhou WM, Song W, Dong H, Shi YQ, Zhou KS, Zhang HH
The American journal of pathology 2025 Oct;195(10):1905-1920
The American journal of pathology 2025 Oct;195(10):1905-1920
Echinacoside suppresses macrophage lipid accumulation and attenuates atherosclerosis via the MDM2/PPARγ/ABCA1 signaling axis.
Zhou QY, Zhou J, Li ZB, Wang Q, Gong D, Liu W, Tang CK
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Oct;1870(7):159681
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Oct;1870(7):159681
Prunella vulgaris polyphenols alleviate atherosclerosis by regulating lipid metabolism via suppressing STAT3 and activating the PI3K-Akt pathway.
Sun T, Yuan W, Li X, Xia B, Huang J, Piao M, Chen W, Tuo Q
Fitoterapia 2025 Oct;186:106848
Fitoterapia 2025 Oct;186:106848
Galangin alleviates vitiligo by targeting ANXA2 degradation in macrophages.
Wei W, Alimujiang A, Zhang Z, Wusiman Z, Liu X, Zhu Y, Bai Y, Zhu Z, Li Z, Xu D, Huo S
British journal of pharmacology 2025 Oct;182(19):4647-4667
British journal of pharmacology 2025 Oct;182(19):4647-4667
Anti-β2GPI antibodies induce trophoblast pyroptosis and placental inflammation through TLR4/NLRP3/GSDMD axis.
Xu M, Ji X, Zhang H, Zeng D, Zhao Z, Liu J, Zhang L, Dong T, Chen P, Wang X
Placenta 2025 Oct;170:64-74
Placenta 2025 Oct;170:64-74
Brusatol suppresses malignant progression of glioma via modulating the miR-574-5p/USP10/PLK1 axis.
Ma B, Wang L, Li J, Zhang B, Wang Y, Li N, Shen D, Han C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157142
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157142
Network pharmacology and transcriptomics reveal complanatoside A regulates lipid metabolism in hyperlipidemia and nonalcoholic fatty liver disease via the AMPK pathway.
Jiang S, Liang Z, Hua J, Li Y, Fan X, Qiao Z, Wang Z, Shen Y, Fan L, Wang J
The Journal of nutritional biochemistry 2025 Oct;144:109960
The Journal of nutritional biochemistry 2025 Oct;144:109960
NSUN2-mediated m5C hypermethylation of hsa_circ_0004516 promotes breast cancer brain metastasis by activating AKT signaling.
Li M, Li J, Wen H, Li J, Wang S, Guo J, Zhang D, Zhang A, Cui C, Fu R, An M, Zhang W, Fu B
Non-coding RNA research 2025 Oct;14:177-190
Non-coding RNA research 2025 Oct;14:177-190
Silibinin attenuates 3-nitropropionic acid-induced ovarian toxicity by alleviating oxidative stress and granulosa cell apoptosis.
Gai Y, Wu W, Wang H, Li Y, Li C, Wang Y, Zhao Y, Hu J, Luan X
Reproductive toxicology (Elmsford, N.Y.) 2025 Oct;137:109027
Reproductive toxicology (Elmsford, N.Y.) 2025 Oct;137:109027
LARS1 lactylation inhibits autophagy by activating mTORC1 to promote podocytes injury in diabetic kidney disease.
Fan Z, Zhang Y, Yuan L, Gao Y, Tian X, Tian J, Wan J, Li B, Wang X, Wang S, Zhang L, Wang L, Zhou P, Liu W
Cellular signalling 2025 Oct;134:111955
Cellular signalling 2025 Oct;134:111955
Overexpression of Rap1B alleviate central precocious puberty and neurodevelopmental damage.
Liu X, Zeng L
Cellular signalling 2025 Oct;134:111941
Cellular signalling 2025 Oct;134:111941
PPP1CA promotes hepatocellular carcinoma progression in a YAP1-dependent way.
Liu X, Xu G, Luo W, Wang K, Wang F
Cellular signalling 2025 Oct;134:111938
Cellular signalling 2025 Oct;134:111938
Wnt/ERK/CDK4/6 activation in the partial EMT state coordinates mammary cancer stemness with self-renewal and inhibition of differentiation.
Liang H, Benard O, Kumar V, Griffen A, Ren Z, Sivalingam K, Wang J, de Simone Benito E, Zhang X, Zhang J, Suyama K, LaFave LM, Norton L, Hazan RB
British journal of cancer 2025 Oct;133(7):986-1002
British journal of cancer 2025 Oct;133(7):986-1002
Activated Peripheral CD8 + T Lymphocytes Inhibit the Proliferation of Hippocampal Neural Stem Cells via the IFN-γ/JAK/STAT Signaling Pathway.
Li X, Sun X, Hao S, Wang G, Guo Y, He Y, Zhang Q, Feng Z, Wang G, Liu C
Immunity, inflammation and disease 2025 Oct;13(10):e70287
Immunity, inflammation and disease 2025 Oct;13(10):e70287
Upadacitinib regulates pain-related pathways and BDNF expression in human monocyte-derived microglial-like cells.
Vomero M, Corberi E, Berardicurti O, Currado D, Trunfio F, Saracino F, Marino A, Frascà L, Gatti M, Imperatori G, La Barbera L, Krashia P, D'Amelio M, Giacomelli R, Navarini L
Brain, behavior, and immunity 2025 Oct;129:778-786
Brain, behavior, and immunity 2025 Oct;129:778-786
Enhanced Adeno-Associated Virus Production in HEK293 Cells via Dual Inducible Control of Cap and Rep Proteins.
Ren H, Nie J, Song Z, Yang Y, Bai Z
Biotechnology and bioengineering 2025 Oct;122(10):2862-2873
Biotechnology and bioengineering 2025 Oct;122(10):2862-2873
ZDHHC12 Palmitoylates HDAC8 to Promote the Progression of Hepatocellular Carcinoma Associated with a Diet High in Saturated Fatty Acids.
Jin X, Hong Y, Zhao Y, Shi W, Liu R, You X, Yang C, Zhang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(40):e05702
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(40):e05702
Inhibition of the 4-hydroxynonenal-regulated JNK/c-Jun pathway improves bleomycin-induced lung fibrosis.
Liu CC, Lin JH, Hsu TW, Wang CY, Hsu HS
Biomedical journal 2025 Oct 9;:100916
Biomedical journal 2025 Oct 9;:100916
Loss of non-canonical translation initiation factors impairs perinatal cardiac function in mice.
Asai T, Tochinai R, Tsuru Y, Sekiguchi M, Minami A, Fujii W, Kyuwa S, Ogawa T, Kakuta S
Experimental animals 2025 Oct 8;74(4):429-439
Experimental animals 2025 Oct 8;74(4):429-439
The Interventional Effects and Mechanisms of Lonidamine in Combination with Apigenin on Colorectal Cancer.
Zhou Y, Shi J, Zhang M, Yang H, Fei J
Current issues in molecular biology 2025 Oct 8;47(10)
Current issues in molecular biology 2025 Oct 8;47(10)
Soluble MFGE8 mediates cell entry of Crimean-Congo hemorrhagic fever virus.
Ma X, Xu Z-S, Fu Y, Ma Y, Du W-T, Li Q, Zhan R, Tian S, Yang L, Wang Z, Feng F, Gao Z, Wang M, Cao S, Wang Y-Y, Zhang R
mBio 2025 Oct 8;16(10):e0161725
mBio 2025 Oct 8;16(10):e0161725
Fosl2 facilitates chromatin accessibility to determine developmental events during follicular maturation.
Zhang H, Li Z, Zhu Y, Lyu W, Wei W, Wang H, Tian S, Yue W, Zhong J, Sun QY, Guan Y
Nature communications 2025 Oct 8;16(1):8955
Nature communications 2025 Oct 8;16(1):8955
cGAS-STING pathway mediates TiO(2) nanoparticle-induced TM4 cell apoptosis via MCUb downregulation and calcium overload.
Li P, Sun C, Wang Q, Hu Y, Song G
Toxicology and applied pharmacology 2025 Oct 7;505:117591
Toxicology and applied pharmacology 2025 Oct 7;505:117591
ATG16L1 controls mammalian vacuolar proton ATPase.
Duque TLA, Paddar M, Trosdal E, Javed R, Allers L, Mudd MH, Akepati P, Mishra SR, Salemi M, Phinney B, Bratton SB, Wileman T, Deretic V
The Journal of cell biology 2025 Oct 6;224(10)
The Journal of cell biology 2025 Oct 6;224(10)
SIRT3 mediates Tubeimoside I's inhibition on pulmonary artery smooth muscle cell proliferation and oxidative stress in pulmonary arterial hypertension.
Li Y, Zhang Y, Chen Y, Qiao Z, Wang D, Yang Y, Huang W, Yan J
European journal of pharmacology 2025 Oct 5;1004:177938
European journal of pharmacology 2025 Oct 5;1004:177938
ZWINT down-regulated by miR-495-3p inhibited lung metastasis of breast cancer by blocking p38 MAPK signaling pathway activation.
Shao MT, Li WW, Li Y, Chen P, Yu SS, Lu WJ, Chen CM, Dong Y, Zhang YW, Zhang QC
Human cell 2025 Oct 4;38(6):170
Human cell 2025 Oct 4;38(6):170
ATP citrate lyase (ACLY) promotes the occurrence of gastric cancer through regulating lipid metabolism.
Zhang S, Liu Y, Zhang X, Zhang N, Sun J, Chen P
Translational cancer research 2025 Oct 31;14(10):6975-6989
Translational cancer research 2025 Oct 31;14(10):6975-6989
Epigallocatechin gallate improves insulin sensitivity in rats experiencing catch-up growth after being small for gestational age by upregulating PDX1 expression.
Wang Y, Wu X, Chen L, Mao S
Translational pediatrics 2025 Oct 31;14(10):2437-2447
Translational pediatrics 2025 Oct 31;14(10):2437-2447
Temporally increased 4-sulfated chondroitin sulfate promotes proper progression of bone morphogenetic protein 4-mediated chondrogenic differentiation.
Mikami T, Takenaka H, Morita T, Kitagawa H
Biochemical and biophysical research communications 2025 Oct 30;786:152713
Biochemical and biophysical research communications 2025 Oct 30;786:152713
ANK3 Is Regulated by Recursive Splicing and Inhibits Hepatocellular Carcinoma Metastasis by Inhibiting E-Cadherin Protein Degradation.
Guo Y, Fu X, Tian Y
Frontiers in bioscience (Landmark edition) 2025 Oct 30;30(10):46013
Frontiers in bioscience (Landmark edition) 2025 Oct 30;30(10):46013
Lactate-binding protein DNMT3A in HRMECs promotes angiogenesis by upregulating VEGFA through HIF-1α lactylation.
Wang X, Huang J, Fan W, Li N, Yang H, Yang W, Li W, Li R, Liu J, Li X, Zhou Q, Hou S
Genome biology 2025 Oct 30;26(1):377
Genome biology 2025 Oct 30;26(1):377
Notoginsenoside R1 attenuates idiopathic pulmonary fibrosis through neuropilin-1/type 2 innate lymphoid cells pathway.
Yang M, Fang Y, Li X, Yang B, Ma Q, Cui X, Jiang L, Ge F
International immunopharmacology 2025 Oct 30;164:115385
International immunopharmacology 2025 Oct 30;164:115385
Arginyl-fructosyl-glucose (AFG), a major Maillard reaction product of red ginseng, improved kidney and pancreatic injury in vitro and in vivo in type 2 diabetes mellitus.
Tsopmejio ISN, Tang S, Gao XF, Liu Z, Li XD, Qi MH, Zhu HY, Wang Z, Li W
International immunopharmacology 2025 Oct 30;164:115378
International immunopharmacology 2025 Oct 30;164:115378
RECQL1 as a potential therapeutic target for PARP inhibitor-resistant ovarian cancer.
Yoshida H, Li J, Inui H, Rokugawa K, Fujiwara K
Scientific reports 2025 Oct 30;15(1):38089
Scientific reports 2025 Oct 30;15(1):38089
Chidamide impedes glycolysis but increases ferroptosis and cisplatin sensitivity of lung cancer cells through downregulating USP35.
Wang K, An L, Zang A, Huo Y
BMC cancer 2025 Oct 3;25(1):1504
BMC cancer 2025 Oct 3;25(1):1504
Synergistic potential of Berberine and Wogonin improved adipose inflammation and insulin resistance associated with obesity through HIF-α axis.
Zhou Z, Wang M, Zhang X, Xu Y, Li P, Zheng Z, Yang H
Chinese medicine 2025 Oct 3;20(1):155
Chinese medicine 2025 Oct 3;20(1):155
STBD1 mediates the crosstalk between glycogen and lipid droplets in clear cell renal cell carcinoma.
Wang H, Xiao T, Zhuang H, Liu Y, Jin K, Li J, Li J, Gao Y, Yue D, Cui W, Xu Q, Pan J, Liu K, Wang Y, Chen R, Li H
Cell reports 2025 Oct 28;44(10):116429
Cell reports 2025 Oct 28;44(10):116429
Mycobacterium bovis induces macrophage mitochondrial release of hexokinase 2 to enhance intracellular survival.
Li L, Chen Y, Wang Y, Dong Y, Wang H, Liu Z, Ge X, Shen P, Li Y, Liu D, Zhou X
Cell reports 2025 Oct 28;44(10):116421
Cell reports 2025 Oct 28;44(10):116421
The activation of hippocampus microglia in the occurrence of airway hyperresponsiveness comorbidity anxiety.
Zhang H, Zhou Y, Liu Y, Zhao K, Chen H, Liu Q, Wang Q, Zhi J, Xu J, Yang D
Journal of neuroinflammation 2025 Oct 28;22(1):249
Journal of neuroinflammation 2025 Oct 28;22(1):249
Villin like suppresses nasopharyngeal carcinoma proliferation by downregulating MYC.
Wen Y, Zhou Z, Zhou Y, Huang Z
Scientific reports 2025 Oct 28;15(1):37628
Scientific reports 2025 Oct 28;15(1):37628
Iron overload-induced ferroptosis in CD8(+) T cells leads to functional abnormalities that promote endometriosis progression.
Wang S, Xu L, Jiao X, Dong X, Zhong Z, Ren Q, Liu X, Yuan M, Wang G
BMC medicine 2025 Oct 27;23(1):588
BMC medicine 2025 Oct 27;23(1):588
Neuroprotective Effects and Mechanisms of Arecoline Against H(2)O(2)-Induced Damage in SH-SY5Y Cells.
Zhang X, Cui J, Sun J, Wang F, Fan B, Lu C
International journal of molecular sciences 2025 Oct 24;26(21)
International journal of molecular sciences 2025 Oct 24;26(21)
Steamed Panax notoginseng Saponins Ameliorate Cyclophosphamide-Induced Anemia by Attenuating Gut-Liver Injury and Activating the cAMP/PI3K/AKT Signaling Pathway.
Xu C, Cui H, Fang Q, Tu P, Cui X
Nutrients 2025 Oct 23;17(21)
Nutrients 2025 Oct 23;17(21)
Bioinformatics analysis of IFI6 as a novel prognostic biomarker and its correlation with immune infiltration in breast cancer.
Jiang L, Xing C, Li M, Zhao Z
Scientific reports 2025 Oct 17;15(1):36446
Scientific reports 2025 Oct 17;15(1):36446
O-GlcNAc transferase influences the progression of degenerative cartilage disease in lumbar facet joint osteoarthritis through FoxO1 and EGR1.
Chen C, Gao Y, Xu G, Sun Y, Bao G, Liu W, Xu D, Yuan K, Cui Z
Cell death discovery 2025 Oct 16;11(1):462
Cell death discovery 2025 Oct 16;11(1):462
OPA1 modulates NLRP3 inflammasome activation and microglial-mediated neuroinflammation in neonatal hypoxic-ischemic brain injury.
Lv Q, Hong F, Sun Z, Shen H, Lu H, Jin Y, Mao L, Song L
Journal of neuroimmunology 2025 Oct 15;407:578701
Journal of neuroimmunology 2025 Oct 15;407:578701
Notch activation downregulates EZH2 to thereby attenuate endothelial cell proliferation and angiogenesis via MYC destabilization.
Duan Y, Wen T, Ma J, Chen Y, Liang L, Yang Z, Zhang P, Zhang Q, Li M, Feng X, Jia D, Luo S, Sun J, Han H, Yan X
Life sciences 2025 Oct 15;379:123889
Life sciences 2025 Oct 15;379:123889
Whole-transcriptome sequencing analysis of spinal neuronal ferroptosis in aggravating neuropathic pain.
Gao X, Liang X, Gao L, Zhang Y, Zhang L, Jia S, Zhang B, Meng C
Life sciences 2025 Oct 15;379:123882
Life sciences 2025 Oct 15;379:123882
CXCL10 modulates airway inflammation in asthma via Sirt3-dependent macrophage homeostasis.
Ding W, Wang P, Ding Z, Yang B, Huo S, Lin P, Zhao J, Xu Y, Ding S
Life sciences 2025 Oct 15;379:123849
Life sciences 2025 Oct 15;379:123849
Structural elucidation of an unusual acid heteropolysaccharide with moieties of glucuronogalactoarabinan and glucuronoarabinogalactan from young shoots of Aralia elata (Miq.) Seem.
Liang J, Ji MC, Jiang SL, Ban XT, Liu X, Shang XW, Zhang Y, Huang YX, Kuang HX, Xia YG
Carbohydrate polymers 2025 Oct 15;366:123794
Carbohydrate polymers 2025 Oct 15;366:123794
Epigenetic regulation by WTAPP1 promotes trophoblast dysfunction in gestational diabetes via CNR1/NF-κB activation.
Yang N, Li Y, Zhang J, Gao X, Zhang P, Li W
European journal of medical research 2025 Oct 15;30(1):975
European journal of medical research 2025 Oct 15;30(1):975
Functional metabolomics revealed pyroglutamic acid may play a key role in idiopathic pulmonary fibrosis.
Wen Y, Nie JH, Qin XM, Li ZY
Journal of pharmaceutical and biomedical analysis 2025 Oct 15;264:116967
Journal of pharmaceutical and biomedical analysis 2025 Oct 15;264:116967
Tssk6 is essential for the regulation of male zebrafish fertility.
Ma X, Qi Y, He H, Yuan C, Huang D
Theriogenology 2025 Oct 15;246:117547
Theriogenology 2025 Oct 15;246:117547
Histone H3 lysine 18 lactylation attenuates neuroinflammation and neurological damage by regulating microglial plxnb2 after ischemic stroke.
Li P, Wang Y, Xu Y, Feng L, Jiang N, Fang Y, Song G, Yu L, Xu L, Zhu Z, Zhu S, Wang W, Xie M
Neurobiology of disease 2025 Oct 15;215:107061
Neurobiology of disease 2025 Oct 15;215:107061
Oxyberberine alleviates fructose-induced hyperuricemia by modulating purine metabolism and gut microbiota.
Tan W, Xie X, Yu Q, Yan G, Chen H, Xie Q, Liu Y, Huang X, Chen J, Xie J, Su Z, Li Y
European journal of pharmacology 2025 Oct 15;1005:178061
European journal of pharmacology 2025 Oct 15;1005:178061
Aβ-damaged neural stem cells migration and differentiation through Wnt3a/β-catenin pathway: Protective effects of 17β-E2.
Yang Y, Zhang L, Zhao Y, Chen Z, Wang P, Yang Z
Neuroscience letters 2025 Oct 14;865:138350
Neuroscience letters 2025 Oct 14;865:138350
miR-423-3p inhibits CTNNBIP1/WNT preventing hyperandrogenic polycystic ovary syndrome†.
Zhang S, Liu Y, Wang M, Ponikwicka-Tyszko D, Wolczynski S, Chen L, Huang X, Yao B, Rahman NA, Li X
Biology of reproduction 2025 Oct 14;113(4):856-869
Biology of reproduction 2025 Oct 14;113(4):856-869
RAPGEF6 is a key biomarker with temporal characteristics in sepsis and exacerbates inflammation and oxidative stress by NF-κB-mediated necroptosis.
Fang Y, Chen H, Yang X, Lu Y, Wu L, Sun Z, Ouyang X, Wan W, Liu Z, Zhao N, Tao W, Liu F
Functional & integrative genomics 2025 Oct 13;25(1):209
Functional & integrative genomics 2025 Oct 13;25(1):209
Betulinic acid protects against LPS-induced intestinal inflammatory damage via inhibiting Nrf2/TXNIP/NLRP3 signaling pathways in mice.
Zhu L, Kong L, Huang Y, Ou Z, Huang C, Yang W, He J, Yang M, Liu S, Yi J
Food & function 2025 Oct 13;16(20):8048-8060
Food & function 2025 Oct 13;16(20):8048-8060
Research on the Protective Effects and Mechanisms of Gallic Acid Against Cognitive Impairment Induced by Chronic Sleep Deprivation.
Zhang X, Cui J, Sun J, Wang F, Fan B, Lu C
Nutrients 2025 Oct 12;17(20)
Nutrients 2025 Oct 12;17(20)
Preventive and Therapeutic Effects of Hydrogen-Generating Si-Based Agent on Pressure Ulcers in Mice.
Otani N, Oue T, Kobayashi Y, Kobayashi H, Tomita K, Kubo T
Biomedicines 2025 Oct 11;13(10)
Biomedicines 2025 Oct 11;13(10)
Lipin3 deficiency promotes hepatocyte ferroptosis and pyroptosis via activating JAK1-STAT3 pathway during acetaminophen induced acute liver injury.
Liu YX, Wang Q, Xiangyang ZY, Long JY, Huang H, Fan LL
Molecular biomedicine 2025 Oct 10;6(1):78
Molecular biomedicine 2025 Oct 10;6(1):78
EDC4 enhances multi-drug chemosensitivity in pancreatic cancer via GR50-based profiling.
Qin C, Li T, Zhao B, Li Z, Zhao Y, Zhang X, Xie Y, Yan Y, Han J, Shao Q, Lin C, Wang W
Cancer cell international 2025 Oct 10;25(1):347
Cancer cell international 2025 Oct 10;25(1):347
NEK7 mediates ESRD-associated endothelial injury by activating the NLRP3 inflammasome.
Sun L, Ren Y, Zhu W, Ni T, Huang S, Zhang A, Zhang Y, Hua H, Jia Z, Sun Z
International immunopharmacology 2025 Oct 10;163:115236
International immunopharmacology 2025 Oct 10;163:115236
Andrographolide attenuates oxidative stress and apoptosis in osteoporosis rats via MEK/ERK and Beclin-1/ATG-5-mediated autophagy pathway.
Li Y, Li G, Luo R, Li B
The Journal of pharmacy and pharmacology 2025 Oct 1;77(10):1426-1438
The Journal of pharmacy and pharmacology 2025 Oct 1;77(10):1426-1438
A hydrogel tissue adhesive incorporating basic fibroblast growth factor-loaded liposomes accelerates cutaneous wound healing by enhancing cell proliferation, collagen synthesis and angiogenesis.
Geng Y, Gao Y, Qi D, Wang Z, Zou Z, Zhang Z, Lian J, Zhang Z, He C, Shao Y
Acta biomaterialia 2025 Oct 1;205:242-259
Acta biomaterialia 2025 Oct 1;205:242-259
A Phototherapy Nanosensitizer-Unlocked Multihit Strategy to Inhibit Tumor Stemness and Potentiate Sorafenib Response in Hepatocellular Carcinoma.
Qin T, Lu H, Wang Q, Deng Y, Zeng J, Chen Y, Liao X
ACS applied materials & interfaces 2025 Oct 1;17(39):54537-54552
ACS applied materials & interfaces 2025 Oct 1;17(39):54537-54552
Bioinspired Multifunctional Hydrogel Loaded with Netrin-1 for Diabetic Wound Healing.
Chen J, Wang X, Yuan X, Zou H, Li J, Chen G, Tan Q
ACS applied materials & interfaces 2025 Oct 1;17(39):54525-54536
ACS applied materials & interfaces 2025 Oct 1;17(39):54525-54536
Rutin Enhances Intestinal Barrier Function and Protects Against X-Ray Radiation-Induced Barrier Dysfunction in Human Epithelial Caco-2 Cells.
Park HY, Yu JH, Shin SB, Kim YM
Molecular nutrition & food research 2025 Nov;69(22):e70235
Molecular nutrition & food research 2025 Nov;69(22):e70235
FAM111B enhances glycolysis and promotes metastasis of prostate cancer by upregulating LDHA.
He Q, Li H, Cong Y, Chen K, Cheng L, Lv F, Zhang P, Ju Y, Yu Z, Chen J, Wang C, Song Y, Li X, Chen L, Xing Y
Neoplasia (New York, N.Y.) 2025 Nov;69:101227
Neoplasia (New York, N.Y.) 2025 Nov;69:101227
SELENBP1 protects against kidney fibrosis in chronic kidney disease as a methanethiol oxidase.
Zhang Y, Zha D, Liu C, Yang W, Zuo Y, Jiang J, Gong Y, He Q
Science China. Life sciences 2025 Nov;68(11):3303-3318
Science China. Life sciences 2025 Nov;68(11):3303-3318
Generation of Ext1 Gene-Edited Mice Model Via Dual sgRNAs/Cas9 System and Phenotypic Analyses.
Zhou L, Li X, Ji Z, Zhou C, Yang L, Li Y, Fu C, Gu L, Zhang S, Gao J, Yue P, Yu H
Molecular biotechnology 2025 Nov;67(11):4233-4246
Molecular biotechnology 2025 Nov;67(11):4233-4246
SP1-Mediated upregulation of CLEC18B promotes the proliferation and metastasis of glioma through regulation of the Wnt/β-Catenin/EMT Pathway.
Liu H, Zhu B, Cui Y, Liu W, Xu Q, Lu X, Tan Z, Tian Y, Xu W
Translational oncology 2025 Nov;61:102515
Translational oncology 2025 Nov;61:102515
Gut microbiome contributes to 6PPD-quinone induced cognitive impairment through PI3K/Akt signaling.
Zhu X, Xu Y
Toxicology 2025 Nov;517:154217
Toxicology 2025 Nov;517:154217
Lactate Prevents Glucose Deprivation-Induced Parthanatos in Gastric Cancer Cells Through Alleviating Intracellular Reactive Oxygen Species.
Niu D, Xia Y, Qin X, Zhang M, Pan S, Yuan X, Tang G, Ai W, Liang Y, Li Z, Xie Z
Cell biology international 2025 Nov;49(11):1441-1453
Cell biology international 2025 Nov;49(11):1441-1453
Low Wall Shear Stress Promotes Atheroma via Arterial Iron Accumulation.
Zheng L, Zhang Z, Liu Y, Cheng C, Zhao B, Ji R, Chen Z, Yang L, Cai J, Li K, Qiao T
Arteriosclerosis, thrombosis, and vascular biology 2025 Nov;45(11):1983-1996
Arteriosclerosis, thrombosis, and vascular biology 2025 Nov;45(11):1983-1996
Preprotective Effects of Cardamomin From Amomum villosum Lour. on H(2)O(2) -Induced Oxidative Damage In Vitro and Cerebral Ischemic Stroke In Vivo.
Zhu M, Sun D, Wang H, Li Y, Li H, Chen L
Phytotherapy research : PTR 2025 Nov;39(11):5378-5390
Phytotherapy research : PTR 2025 Nov;39(11):5378-5390
Icariside II Ameliorates Depression Induced by High-Fat Diet via the Microbiota-Gut-Brain Axis in Mice.
Luo YM, Dong L, Li YL, Lin M, Xie DY, Gao JM, Zhang YD, Zhu YZ, Gong QH
Phytotherapy research : PTR 2025 Nov;39(11):5159-5173
Phytotherapy research : PTR 2025 Nov;39(11):5159-5173
PSAT1 knockdown mediated VDAC1 oligomerization promotes ferroptosis and suppresses cell proliferation in esophageal squamous cell carcinoma.
Ren R, Fan T, Li Y, Li C, Jin F, Gao H, Wang X, Xu Y, Li X, Li S, Liu H
International journal of biological macromolecules 2025 Nov;330(Pt 4):148112
International journal of biological macromolecules 2025 Nov;330(Pt 4):148112
The β-glucan from Lentinus alleviates UVB-induced dermal fibroblasts senescence and skin photoaging.
Wei K, He L, Li X, Wu M, Wang H, Hu L, Xu H, Zhang Y, Zhou L, Xu X, Guo L
International journal of biological macromolecules 2025 Nov;329(Pt 2):147834
International journal of biological macromolecules 2025 Nov;329(Pt 2):147834
Fingolimod Exerts Therapeutic Effects on Autistic Mice via Improving the Structure and Function of Meningeal Lymphatics.
Hong C, Xiao HL, Sun ZH, Guo RB, Zhang XY, Ji J, Sun XL
CNS neuroscience & therapeutics 2025 Nov;31(11):e70649
CNS neuroscience & therapeutics 2025 Nov;31(11):e70649
FXR suppress Müller cell activation by regulating cGAS/STING pathway in diabetic retinopathy.
Wang ZL, Zhang XY, Tan CY, Zhuang M, Zhu L, Zheng XH, Yao Y, Wei TT
The FEBS journal 2025 Nov;292(22):6035-6053
The FEBS journal 2025 Nov;292(22):6035-6053
Ginsenoside Compound K Inhibits Wnt/β-Catenin Signaling and Anti-Angiogenesis, Alleviating Joint Injury in Rats With Adjuvant Arthritis.
Xu X, Zeng X, Zhang Y, Liu M, Wei W, Chen J
International journal of rheumatic diseases 2025 Nov;28(11):e70460
International journal of rheumatic diseases 2025 Nov;28(11):e70460
The integrated treatment of photodynamic therapy and oncolytic Virotherapy: A dual-modal paradigm for breast Cancer.
Li Y, Wang K, Min Q, Lu H, Zhang G, Yan J
Journal of photochemistry and photobiology. B, Biology 2025 Nov;272:113248
Journal of photochemistry and photobiology. B, Biology 2025 Nov;272:113248
MTHFD2 drives retinoblastoma progression via Notch signaling activation: Implications for targeted pediatric ocular cancer therapy.
Yao C, Chen T, Chen Y, Wu W, Li Y, Zhang Y, Huang G
Experimental eye research 2025 Nov;260:110579
Experimental eye research 2025 Nov;260:110579
Very high-dose vitamin D₃ supplementation reduces the expression of genes and proteins engaged in β-oxidation in healthy pigs.
Steg A, Smołucha G, Świątkiewicz M, Oczkowicz M
The Journal of steroid biochemistry and molecular biology 2025 Nov;254:106835
The Journal of steroid biochemistry and molecular biology 2025 Nov;254:106835
TBRG4 regulates ubiquitination of Beclin1 and participates in autophagy pathway to inhibit intervertebral disc degeneration.
Cui X, Zhang F, Cui D, Zhang W, Wu H, Chen X, Yu H
The spine journal : official journal of the North American Spine Society 2025 Nov;25(11):2569-2584
The spine journal : official journal of the North American Spine Society 2025 Nov;25(11):2569-2584
Astragalin induces immunogenic cell death in liver cancer by targeting NQO2 to promote ROS-mediated endoplasmic reticulum stress pathway.
Zheng L, Zhao Z, Chen L, Yang W, Ercolani G, Qin P, Lin B, Han M, Weng Q, Zhang Y, Wu B, Chen M, Yao Z, Fang S, Ji J
Free radical biology & medicine 2025 Nov;239:317-335
Free radical biology & medicine 2025 Nov;239:317-335
Treadmill exercise alleviates STING-mediated microglia pyroptosis and polarization via activating mitophagy post-TBI.
Chen J, Zhu T, Yang X, Yang Z, Shen M, Gu B, Wang D, Zhang Y, Zhang M, Sun S, Yu J, Yan C
Free radical biology & medicine 2025 Nov;239:155-176
Free radical biology & medicine 2025 Nov;239:155-176
Role of IL33/HIF1α/VEGF in intermittent hypoxia-induced lung injury.
Zhang Y, Yu WY, Ma ZX, Kang L, Yao QL, Sun Z, Ma XJ
Immunobiology 2025 Nov;230(6):153132
Immunobiology 2025 Nov;230(6):153132
Study on the Specifications of Scutellariae Radix in Da-Chai-Hu-Tang Based on Efficacy in a Rat Model of Large Intestine Damp-Heat Syndrome and Chemical Composition Differences.
Shao W, Lian T, Xie W, Wang Y, Li H, Yang D, Nie X, Zhou M, Liu F, Wei S, Zhang Y
Chemistry & biodiversity 2025 Nov;22(11):e01198
Chemistry & biodiversity 2025 Nov;22(11):e01198
Collagen peptides from Skipjack tuna (Katsuwonus pelamis) bones: Composition, characterization, and mechanism of high-fat diet-induced NAFLD amelioration.
Jiang YL, Zhang SY, Wang B, Zeng YH, Xu L, Chi CF
Food research international (Ottawa, Ont.) 2025 Nov;219:117114
Food research international (Ottawa, Ont.) 2025 Nov;219:117114
BMAL1 modulates respiratory syncytial virus-induced inflammation through p38 mitogen-activated protein kinase pathway: insights into circadian regulation.
Wang L, Yao J, Zhuo X, Chen L, Jiang Z, Liu H
Microbial pathogenesis 2025 Nov;208:107954
Microbial pathogenesis 2025 Nov;208:107954
Subacute exposure to thallium disrupts renal energy metabolism by impairing the function of subcellular organelles in aged mice of both sexes.
Yao H, Li L, Dai Q, Li D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Nov;205:115700
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Nov;205:115700
Elafin inhibits macrophage activation by blocking a chloride channel.
Li X, Chen L, Chen N, Xu L, Cui X, Wang F
Biochimica et biophysica acta. Molecular basis of disease 2025 Nov;1871(8):167989
Biochimica et biophysica acta. Molecular basis of disease 2025 Nov;1871(8):167989
Mechanism and marker of voriconazole-induced liver injury: insights from a quantitative systems toxicology approach.
Du Q, Qiu Y, Yang L, Wang C, Teng M, Chen J, Luo Y, Sun J, Wang T, Chen S, Dong Y
Regulatory toxicology and pharmacology : RTP 2025 Nov;162:105871
Regulatory toxicology and pharmacology : RTP 2025 Nov;162:105871
Protective Effect of Vinegar Powder on (60)Coγ Radiation-Injured Mice and Its Potential Mechanism.
Huang H, Shi Y, Liu X, Hao L, Zhu J, Lu J
The Journal of nutrition 2025 Nov;155(11):3663-3675
The Journal of nutrition 2025 Nov;155(11):3663-3675
ZC3H13 facilitates the progression of acute myeloid leukemia through m6A-FOXP1-mediated metabolic reprogramming.
Wang J, Xu L, Wang G, Wu W, Kong H
Experimental hematology 2025 Nov;151:104862
Experimental hematology 2025 Nov;151:104862
High glucose induces hippocampal neuron impairment through the SKP1/COX7C pathway: A potential mechanism for perimenopausal depression.
Wang Z, Liu Z, Feng S, Song X, Liu D, Ma N, Zhang X, Liu W, Wang DO, Liu X, Ikejima T
Acta pharmaceutica Sinica. B 2025 Nov;15(11):5832-5853
Acta pharmaceutica Sinica. B 2025 Nov;15(11):5832-5853
Mechanistic insights into baicalein's anti-inflammatory effects in COPD: Targeting oxidative stress and CD8⁺ T cell cytotoxicity.
Xiao X, Guo W, Ding Z, Chen N, Zhang Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157183
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157183
The total xanthones from Gentianella acuta alleviate acute myocardial infarction by targeting BRD4-mediated cardiomyocyte pyroptosis and inflammation.
Dai C, Sun J, Yang G, Zhang C, Zhang Y, Song Q, Liu X, Duan X, Yang H, Li A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157156
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157156
PDCD4 exacerbates myocardial ischemia-reperfusion injury via AKT-mediated apoptosis.
Zhang Z, Yang Z, Ge H, Liu C, Fan R, Yuan C, You S, Hong C
Cellular signalling 2025 Nov;135:111999
Cellular signalling 2025 Nov;135:111999
Regulation of melanogenesis via ubiquitin-proteasome system and autophagy by 3,3,5-trimethylcyclohexyl succinate dimethylamide and tranexamic acid.
Wang J, Zha F, Lin S, Wei Y, Xuan L, Ye Z, Huang H
Journal of dermatological science 2025 Nov;120(2):61-70
Journal of dermatological science 2025 Nov;120(2):61-70
RPS27L Enhances Myogenesis and Muscle Mass by Targeting IGF1 Through Liquid-Liquid Phase Separation.
Liu X, Yao Y, Yan J, Zeng M, Fan X, Tang Y, Li J, Liu Y, Yan S, Wang W, Chen L, Chen R, Huang Y, Calnan H, Wang H, Gardner G, Yang Y, Tang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(44):e12354
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(44):e12354
APOL2 Stabilizes Ku80 to Confer NHEJ-Mediated Radioresistance in Gastric Cancer.
Zu D, Bao Q, He H, Zhong Y, Deng M, Hu Y, Zhang C, Liang C, Huang Y, Liu H, Li X, He Y, Luo G, Wu W, Guan F, Xu S, Liu M, Bacolla A, Jing J, Du Y, Tainer JA, Shi Y, Ye Z, Cheng X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(44):e06294
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(44):e06294
FOXQ1 Regulates Brain Endothelial Mitochondrial Function by Orchestrating Calcium Signaling and Cristae Morphology.
Zou W, Lv Y, Li L, Zhang S, Liang J, Wu C, Huang E, Jiao J, Zhang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(42):e03082
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(42):e03082
Microwave-Activated Bacterial Biorobot for Multimodal Cancer Therapy.
Zhuang H, Zhang Y, Fu Y, Ke D, Chen Q, Shao S, Xue P, Chen Y, Zeng X, Yan S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(41):e04603
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(41):e04603
The duck plague virus UL7 protein mediates RIG-I degradation to block host antiviral responses and promote viral pathogenesis.
Lan X, Hao YY, Wang M, Yang L, Wu L, Cheng A
Poultry science 2025 Nov;104(11):105679
Poultry science 2025 Nov;104(11):105679
Hydrogen activated the Nrf2/HO pathway to alleviate the cognitive decline in PD Drosophila after long-term sevoflurane exposure.
Li M, Ma B, Liang S, Pan X, Xie J, Wang H, Guo J
Neurotoxicology and teratology 2025 Nov-Dec;112:107560
Neurotoxicology and teratology 2025 Nov-Dec;112:107560
Metabolic syndrome-related gene signature for prognosis and immune microenvironment prediction in hepatocellular carcinoma.
Chen L, Wang Y, Li S, Lu S, Luo Y, Ning Y, Chen J, Zhou S
Scientific reports 2025 Nov 7;15(1):39048
Scientific reports 2025 Nov 7;15(1):39048
Leucine Attenuates Osteoarthritis via mTORC1/LXRα-Mediated Macrophage Reprogramming and Rspo2/β-Catenin Axis Suppression.
Zheng K, Zhang J, Liu W, Xu B
Cartilage 2025 Nov 7;:19476035251389178
Cartilage 2025 Nov 7;:19476035251389178
Discovery of novel covalent PI3Kδ inhibitors bearing alaninamide moiety by lysine-targeted covalent strategy.
Yuan B, Ma M, Wu Y, Liu J, Chen M, Lai Y, Zhang SQ, Xin M
European journal of medicinal chemistry 2025 Nov 5;297:117948
European journal of medicinal chemistry 2025 Nov 5;297:117948
Lactobacillus reuteri attenuates methotrexate-induced liver injury via modulation of oxidative stress and inflammation through HO-1/GPX4 and NF-κB/NLRP3 pathways.
Li WR, Li YK, Ren H, Guo Z, Xiao CL, Luo JQ
European journal of pharmacology 2025 Nov 5;1006:178185
European journal of pharmacology 2025 Nov 5;1006:178185
Icariside II ameliorates slow transit constipation by inhibiting macrophage polarization and suppressing the cGAS-STING pathway.
Jiang Z, Yin F, Ping Y, Ma W, Dou X, Li R, Zheng K, Tong Y, Han L, Fu L, Wu B, Sun D
European journal of pharmacology 2025 Nov 5;1006:178166
European journal of pharmacology 2025 Nov 5;1006:178166
DDX1 facilitates lenvatinib resistance in hepatocellular carcinoma through regulating ephrin-A3 and activating the Wnt/β-catenin signaling pathway.
Huang S, Wang H, Fu S, Cheng F, Liu K, Wu J
Functional & integrative genomics 2025 Nov 4;25(1):230
Functional & integrative genomics 2025 Nov 4;25(1):230
The relationship between high serum UA levels and decidualization and angiogenesis in endometrium.
Li J, He M, Huang M, Xiang J, Zhang L, Liu Y, Ma Y, Zeng X, Sun X
Scientific reports 2025 Nov 4;15(1):38574
Scientific reports 2025 Nov 4;15(1):38574
TP53-dependent antitumor effects of DHODH Inhibition in nasopharyngeal carcinoma.
Dong X, Zhang Y, Zhang Z, Liu T, Gu D
Discover oncology 2025 Nov 30;17(1):14
Discover oncology 2025 Nov 30;17(1):14
Lipidomic and transcriptomic analysis and its therapeutic implications in Chinese Kazakh patients with esophageal squamous cell carcinoma.
Sun Q, Liu R, Zhang H, Zong L, Li T, Zhang L
BMC cancer 2025 Nov 3;25(1):1696
BMC cancer 2025 Nov 3;25(1):1696
Dapagliflozin ameliorates high glucose-induced peritoneal fibrosis through downregulation of ENKUR/PI3K/AKT signaling pathway.
Liu J, Xu X, Zhang L, Jiang T, Zhao Z, Xiao J
Scientific reports 2025 Nov 3;15(1):38334
Scientific reports 2025 Nov 3;15(1):38334
Parthenolide Exerts Protection against Hypoxic-Ischemic Brain Damage in Neonatal Rats by Inhibiting Perk-Mediated Endoplasmic Reticulum Stress.
Mao N, Zheng Y, Yuan J, Feng X, Ren Y, Wang X, Tao X, Wang X, Fang M, Lin Z
Molecular neurobiology 2025 Nov 29;63(1):210
Molecular neurobiology 2025 Nov 29;63(1):210
Integrating Functional Genomic Screens and Multi-Omics Data to Construct a Prognostic Model for Lung Adenocarcinoma and Validating SPC25.
Zhang Y, Tan H, Jiang D
Cancers 2025 Nov 29;17(23)
Cancers 2025 Nov 29;17(23)
SKP2 protein as a prognostic biomarker for glioma and promotes tumor progression by regulating the cell cycle.
Guan L, Li H, Liu Y, Ouyang J, Yan C, Liu F
Scientific reports 2025 Nov 28;15(1):42668
Scientific reports 2025 Nov 28;15(1):42668
5-HEPE Ameliorates Aging of Duck Ovarian Granulosa Cells by Targeting FOXM1 and Suppressing Oxidative Stress.
Zong Y, Liu J, Xu W, Gu T, Tian Y, Chen L, Zeng T, Lu L
Antioxidants (Basel, Switzerland) 2025 Nov 27;14(12)
Antioxidants (Basel, Switzerland) 2025 Nov 27;14(12)
CaMKII Drives Synaptic Maturation by Coordinating Spine Remodeling and Receptor Segregation via Liquid-Liquid Phase Separation.
Kuo LMS, Liu PW, Arizono M, Hayashi Y
The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 Nov 26;45(48)
The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 Nov 26;45(48)
Hsa-miR-423-5p selectively loaded in hypoxic exosomes reduces the sensitivity of normoxic hepatocellular carcinoma to sorafenib via autophagy.
Shu B, Zou M, Liao R, Wen D, Gao X, Lu J, Song H, Sheng Z, Liu Z, You Y
Cancer cell international 2025 Nov 26;25(1):425
Cancer cell international 2025 Nov 26;25(1):425
Evolutionary dampening of Wnt signaling may contribute to naturally ascrotal testes in mammals: Dampened Wnt pathway under ascrotal testes.
Chai S, Zhong C, Zhang Z, Yin D, Xu S, Ren W, Yang G
Molecular biology and evolution 2025 Nov 26;
Molecular biology and evolution 2025 Nov 26;
Sagittaria Sagittifolia Polysaccharide Ameliorates Diabetic Retinopathy in Mice via Inhibiting TLR4-Mediated Microglial Activation.
Jiang Y, Zhou M, Zhang J, Liang Y, Ding J, Liao W, Liao Y
Molecular neurobiology 2025 Nov 25;63(1):170
Molecular neurobiology 2025 Nov 25;63(1):170
Enoxaparin alleviates preeclampsia by enhancing trophoblast function via the NSUN2-mediated m(5)C methylation of PAX3 mRNA.
Zhong X, Zeng D
European journal of medical research 2025 Nov 25;30(1):1283
European journal of medical research 2025 Nov 25;30(1):1283
Lineage plasticity and signal dysregulation define the cellular trajectory of osteoarthritis progression.
Chen G, Tai K, Dai G
Clinical and experimental medicine 2025 Nov 25;26(1):41
Clinical and experimental medicine 2025 Nov 25;26(1):41
Identification of a Treg-related gene signature for predicting prognosis and immunosuppression in skin cutaneous melanoma.
Lian C, Jin R, Zhang X
Clinical and experimental medicine 2025 Nov 25;26(1):35
Clinical and experimental medicine 2025 Nov 25;26(1):35
Deferoxamine improves femoral trochlear dysplasia following patellar dislocation through HIF-1α/VEGF-mediated angiogenesis-osteogenesis coupling.
Li Y, Ni Z, Fu T, Xu C, Zhao Z, Kang H, Wang F
Journal of orthopaedic surgery and research 2025 Nov 25;20(1):1034
Journal of orthopaedic surgery and research 2025 Nov 25;20(1):1034
Kaempferol attenuated LPS-induced microglial neurotoxicity by promoting mitophagy to inhibit mtDNA-mediated NLRP3 inflammasome activation.
Xiao L, Liang L, Zhou S, Peng F, Yuan C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157486
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157486
Pulchinenoside E2: A dual-functional STAT3 and autophagy inhibitor with potent anti-metastatic activity in triple-negative breast cancer.
Zheng D, Shu J, Gao B, Yu H, Liu K, Zheng M, Liu X, Chen G, Lin Y, Li Q, Sun Y, Zheng Y, Li B, Yang X, Wang K
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157485
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157485
Syringin attenuates Alzheimer's disease-associated neuroinflammation by inhibiting NLRP3 inflammasome activation.
Xu Z, Huang F, Wu Z, Xu K, Huang L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157454
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157454
Kang Shuai Lao Pian exerts anti-aging effects by enhancing mitochondrial oxidative metabolism.
Wang X, Zhang K, Ni J, Deng H, Zhao Z, Wang Z, Li L, Chen F, Li T, Liu L, Fan G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157376
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157376
Combined transcriptomics and network pharmacology to elucidate the mechanisms of rutin in treating ischemic stroke rat.
Zheng T, Jiang T, Chen Y, Xie J, Yu W, Wang M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157267
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157267
Germacrone Ameliorates Diabetic Kidney Disease by Activating TFEB to Promote Autophagy and Inhibit Inflammation.
Xie Z, Wang M, Song Q, Su X, Chen JJ, Xu J, Zhang Z, Liu T, Zhang X, Gao G
ACS omega 2025 Nov 25;10(46):55252-55264
ACS omega 2025 Nov 25;10(46):55252-55264
MiR-503-5p mediates cell cycle arrest and fibrosis of peritoneal mesothelial cells with a high peritoneal solute transport status.
Ji O, Xie Y, Lin Y, Li R, Tong Y, Li P, Fang J, Liu Y
BMC nephrology 2025 Nov 24;26(1):662
BMC nephrology 2025 Nov 24;26(1):662
Quercetin's regulation of glucose and lipid metabolism in gestational diabetes mellitus: role of the PCSK9/LDLR axis.
Hong L, Xia S, Chen N, Wang Z, Li Z
Nutrition & metabolism 2025 Nov 24;22(1):159
Nutrition & metabolism 2025 Nov 24;22(1):159
Exploring targeted therapies against RFPL3 for non-small cell lung cancer with lymph node metastasis.
Lin C, Jiang Y, Xu F
Discover oncology 2025 Nov 23;16(1):2275
Discover oncology 2025 Nov 23;16(1):2275
Vasostatin-2 attenuates injury-induced neointimal hyperplasia through the ACE2/MasR/PPARγ/NR1D1/Gas1 axis.
Chen Q, Liu J, Madonna R, Li F, Chen S, Li L, Wu X, Maimati Y, Ding F, Wang X, Shen Y, Zhang R, Shen W, Dai Y, Lu L, De Caterina R
Cardiovascular research 2025 Nov 22;121(14):2260-2277
Cardiovascular research 2025 Nov 22;121(14):2260-2277
Autism-Associated Gut Microbiota-Derived Enterococcus facium Modulates Gut-Brain Axis Function and Behavior in Mice.
Ma R, Ullah H, Bohlooli FS, Wen Y, Xin Y, Wang J, Lu S, Wang L
Pathogens (Basel, Switzerland) 2025 Nov 21;14(12)
Pathogens (Basel, Switzerland) 2025 Nov 21;14(12)
IGFBP7 and CCT2 are novel lactylation-driven mediators of endothelial-to-mesenchymal transition in idiopathic pulmonary fibrosis.
Wenhao L, Ling H, Wanqing F, Wanrong W, Chao C, Ran W
Functional & integrative genomics 2025 Nov 20;25(1):250
Functional & integrative genomics 2025 Nov 20;25(1):250
Oligoclonal tumor-specific CD8 T-cell revival and IRE1α/XBP1-GDF15-mediated immunosuppressive niches determine neoadjuvant chemoimmunotherapy efficacy in cervical cancer.
Cao G, Wang Y, Zeng H, Zhi Y, Guo Y, Xu M, Ruan Y, Wang Y, Xiao Y, Lu J, Tse KY, Gao J, Zhang Q, Wang C, Han Z, Li F
Journal for immunotherapy of cancer 2025 Nov 19;13(11)
Journal for immunotherapy of cancer 2025 Nov 19;13(11)
Resveratrol-Supported Bioenergetics Leads to Higher Productivity and Accompanying Endoplasmic Reticulum Stress in a mAb-Producing CHO Cell Line.
Kurucz B, Hajdinák P, Szarka A
International journal of molecular sciences 2025 Nov 18;26(22)
International journal of molecular sciences 2025 Nov 18;26(22)
Up-regulation of Ifi27l2a expression in bone marrow monocytes contributes to glucocorticoid-induced bone loss.
Wang Z, Huang C, Liu S, Xiao P, Lu Z, Xu Y, Tian Y
Communications biology 2025 Nov 17;8(1):1590
Communications biology 2025 Nov 17;8(1):1590
Circ_0000756 Mediates Oxidative Stress and Metabolic Memory in Diabetic Neuropathy via miR-7b Suppression of NRF2/ARE Pathway.
Chen J, Lu Y, Chen Y, Liu X, Chen W, Zhao P, Yang F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Nov 15;39(21):e71148
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Nov 15;39(21):e71148
Umbilical Cord Mesenchymal Stromal Cell-Derived Extracellular Vesicles Transfer CD59 to Astrocytes to Alleviate Complement-Dependent Cytotoxicity.
Shen Q, Wang X, Ou Q, Wang Q, Zhao Z, Chen Z, Zhu X, Li D, Jin C, Gao F, Wang J, Lu L, Bi Y, Wan W, Guan Y, Xu GT, Xu JY, Tian H
Molecular neurobiology 2025 Nov 14;63(1):41
Molecular neurobiology 2025 Nov 14;63(1):41
Empagliflozin alleviates hepatic ischemia-reperfusion injury by inhibiting c-Myc through the JAK1-STAT3 signaling pathway.
Tulahong A, Xu X, Zhou T, Ruze R, Yuan Z, Qiao P, Jiang T, Aji T, Shao Y
International immunopharmacology 2025 Nov 14;165:115508
International immunopharmacology 2025 Nov 14;165:115508
RNF180 suppressed aggressiveness by degrading NOTCH1, TRIM24 and FOXC1, and chemoresistance by degrading ACC1 and ACLY in colorectal cancer.
Li N, Zhang R, Zhao XX, Zhou L, Li YL, Cui ZG, Zheng HC
International immunopharmacology 2025 Nov 14;165:115445
International immunopharmacology 2025 Nov 14;165:115445
Dual-Targeted Biomimetic Nanoparticles for Enhanced Delivery of Polyphyllin B Synergistically Induce Ferroptosis and Immunogenic Cell Death in Gastric Cancer.
Zu D, Yao J, Li X, Huang Y, Hu C, Deng M, Bao Q, Shi Y, Ye Z, Cheng X
ACS applied materials & interfaces 2025 Nov 12;17(45):61676-61694
ACS applied materials & interfaces 2025 Nov 12;17(45):61676-61694
Unravelling butyrate metabolism in sepsis: identification of key genes.
Zhu Y, Tian F, Ge F, Wang Y, Lu J, Zhou H, Yan Q, Zhang Y, Zhou J, Lu J
BMC infectious diseases 2025 Nov 11;25(1):1546
BMC infectious diseases 2025 Nov 11;25(1):1546
Sex-Specific Involvement of Gut Microbiota in Behavioral and Endocrine Responses to Chronic Predator Odor in Brandt's Voles.
Gu C, Xu R, Yin B, Wu R, Wei Y, Wang D, Wei W
Integrative zoology 2025 Nov 11;
Integrative zoology 2025 Nov 11;
CARMN loss promotes VSMC-derived foam cell formation and atherosclerosis through transcriptional downregulation of autophagy.
Huang T, Tang Y, Su Q, Su C, Wang J, Fu L, Tang Y
Cell death & disease 2025 Nov 10;16(1):815
Cell death & disease 2025 Nov 10;16(1):815
Application of Dental Pulp Stem Cell-Derived Intracellular Vesicles for Diabetic Wound Healing.
Pang P, Liu Y, Song H, Ye Z, Zhou H, Zhang R, Kumeria T, She W, Xu C, Mei PL, He Y, Ye Q
Diabetes 2025 Nov 1;74(11):2060-2074
Diabetes 2025 Nov 1;74(11):2060-2074
Oocyte-specific Ahr deletion disrupts folliculogenesis and female fertility in mice.
Chen P, Ruan J, Xue F, Dai X, Tang C, Chen M, Xiao N, Cai Z, Yang C, He C, Wang W, Zuo Z
Molecular and cellular endocrinology 2025 Nov 1;609:112656
Molecular and cellular endocrinology 2025 Nov 1;609:112656
Formoterol, a clinically approved drug, inhibits ferroptosis by suppressing lipid peroxidation and attenuates APAP-induced acute liver injury.
Teng LS, Ying ZD, Sun XH, Hou HC, Qiu SD, Liu P, Li KJ, Zhang L, Sheng XH
Chemico-biological interactions 2025 Nov 1;421:111724
Chemico-biological interactions 2025 Nov 1;421:111724
Paraquat induced neuro-immunotoxicity: Dysregulated microglial antigen processing and mitochondrial activated mechanisms.
Shi G, Wang K, Liu Q, Wu C, Zhang Q, Ma Y, Qi A, Huang M
Chemico-biological interactions 2025 Nov 1;421:111721
Chemico-biological interactions 2025 Nov 1;421:111721
Gut flora-derived succinate exacerbates Allergic Airway Inflammation by promoting protein succinylation.
Wang C, Yu X, Yu X, Xiao H, Song Y, Wang X, Zheng H, Chen K, An Y, Zhou Z, Guo X, Wang F
Redox biology 2025 May;82:103623
Redox biology 2025 May;82:103623
Molecular biomarkers for the prognosis of breast cancer: role of amino acid metabolism genes.
Zhou Y, Yu S, Zhu L, Wang Y, Duan C, Li D, Du J, Zhang J, Zhang J, Ma R, He J, Ren Y, Wang B
Journal of physiology and biochemistry 2025 May;81(2):441-457
Journal of physiology and biochemistry 2025 May;81(2):441-457
Quercetin Induces Apoptosis Through Downregulating P4HA2 and Inhibiting the PI3K/Akt/mTOR Axis in Hepatocellular Carcinoma Cells: An In Vitro Study.
Zhang J, Guo J, Qian Y, Yu L, Ma J, Gu B, Tang W, Li Y, Li H, Wu W
Cancer reports (Hoboken, N.J.) 2025 May;8(5):e70220
Cancer reports (Hoboken, N.J.) 2025 May;8(5):e70220
Insight of action mechanism of Astragaloside IV for relieving of cerebral ischemic injury in a rat model of middle cerebral artery occlusion reperfusion via proteomics and network pharmacology.
Zhu XH, Yu X, Kong XW, Zhang Y, Jiang SL, Chai JH, Liang J, Kuang HX, Xia YG
Journal of natural medicines 2025 May;79(3):591-607
Journal of natural medicines 2025 May;79(3):591-607
Exogenous α-Synuclein Induces Oxidative Damage to Dopaminergic Neurons Through p-NMDAR2B/Nur77.
Lai X, Wu J, Kou X, Zhang Y, Shen M, Yu M, Zhai Y, Yan J
Molecular neurobiology 2025 May;62(5):5664-5678
Molecular neurobiology 2025 May;62(5):5664-5678
Next-generation sequencing in early-stage multiple primary lung cancer: The prognostic significance of genomic accumulation status and BCL2L11(del).
Wang MT, Ni CH, Lu YQ, Zheng W, Zhang SL, Chen MH, Zheng B, Chen C
Translational oncology 2025 May;55:102383
Translational oncology 2025 May;55:102383
m6A-induced DEAD-box RNA helicase 21 enhances lipid metabolism via 3‑hydroxy-3-methylglutaryl-CoA synthases 1 in colorectal cancer.
Gao H, Zheng S, Liang J, Wang Y, Chen L, Li H, Chen Y, Zhang F, Shi H, Han A
Translational oncology 2025 May;55:102373
Translational oncology 2025 May;55:102373
Dihydroartemisinin ameliorates hemarthrosis-induced cartilage degeneration by suppressing chondrocyte senescence via activation of Keap1-Nrf2 signaling pathway.
Zeng Q, Feng Y, Huang H, Zou K, Chen W, Li X, Huang Y, Wang W, Yuan W, Wang P, Tong P, Jin H, Chen J
Journal of orthopaedic translation 2025 May;52:192-208
Journal of orthopaedic translation 2025 May;52:192-208
Ferulic acid protects against stress-induced myocardial injury in mice.
Li S, He P, Liu J, Zang S, Luo J, Luo Y, Zhu S, Zang L
Toxicology and applied pharmacology 2025 May;498:117309
Toxicology and applied pharmacology 2025 May;498:117309
Sulfasalazine improves neuronal function in mice with ischemic stroke by inhibiting the STING/NF-κB pathway.
Li X, Ding H, Jing J, Qian S, Ma Y, Lv M, Gao Y, Zhang Y, Li T
Naunyn-Schmiedeberg's archives of pharmacology 2025 May;398(5):5797-5810
Naunyn-Schmiedeberg's archives of pharmacology 2025 May;398(5):5797-5810
Daidzein Attenuates Cadmium-Induced Neurotoxicity via Inhibiting Apoptosis and Mitophagy in the Cerebral Cortex of Sprague-Dawley Rats.
Wen S, Zhao Y, Wang L, Yuan Y
Journal of biochemical and molecular toxicology 2025 May;39(5):e70299
Journal of biochemical and molecular toxicology 2025 May;39(5):e70299
Macelignan Improves Functional Recovery After Spinal Cord Injury by Augmenting Autophagy via the AKT-mTOR-TFEB Signaling Pathway.
Zhu Y, Yang S, Su S, Huang Y, Chen Y, Liang H, Miao J, Wu Z, Li X, Xiao J, Wang X
Phytotherapy research : PTR 2025 May;39(5):2091-2109
Phytotherapy research : PTR 2025 May;39(5):2091-2109
HBCOC attenuates cerebral ischemia-reperfusion injury in mice by inhibiting the inflammatory response and autophagy via TREM-1/ERK/NF-κB.
Li R, Li Q, Yang C, Liu H, Xiao Y, Yang P, Gong G, Wu W
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2025 May;34(5):108280
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2025 May;34(5):108280
NAE1 protein: a prognostic, immunomodulatory, and therapeutic biomarker associated with neddylation in hepatocellular carcinoma.
Pan Y, Dai J, Liu Y, Wang Y, Zhang Q, Lou Y, Qiu Y
International journal of biological macromolecules 2025 May;310(Pt 4):143539
International journal of biological macromolecules 2025 May;310(Pt 4):143539
Protective effects of jiawei yupingfeng polysaccharides on cyclophosphamide-induced intestinal injury in mice.
Wu R, Zhao N, Li H, Zhang W, Hua Y, Ji P, Wei Y
International journal of biological macromolecules 2025 May;310(Pt 3):143405
International journal of biological macromolecules 2025 May;310(Pt 3):143405
Poly-IC Alleviates Nitroglycerin-Induced Migraine by Inhibiting Neuroinflammation via TLR3/TRIF Signaling Pathway.
Hong Y, Ma M, Li C, Zhang Y, Li Y, Chen N, Fang J, He L
CNS neuroscience & therapeutics 2025 May;31(5):e70444
CNS neuroscience & therapeutics 2025 May;31(5):e70444
miR-278-3p targets ATG16L1 to modulate autophagy and suppresses CLas proliferation in Diaphorina citri.
Lu L, Feng Q, Wang S, Ghafar MA, Cheng H, Zhou C, Wang L
International journal of biological macromolecules 2025 May;308(Pt 2):142441
International journal of biological macromolecules 2025 May;308(Pt 2):142441
Genome-wide identification of glutathione S-transferase (GST) gene family and its regulating characteristics responding to sperm capacitation in Eriocheir sinensis.
Cui X, Zhang W, Jia Z, Cai X, Fu W, Shen Y, Qiao Y, Zhang X, Wan H, Zhang F, Liu H, Mu S, Guo S, Zhang H, Guo M, Zhang Z, Kang X
International journal of biological macromolecules 2025 May;306(Pt 4):141803
International journal of biological macromolecules 2025 May;306(Pt 4):141803
A novel 5-differentially expressed gene (DEG) signature predicting the prognosis in patients with metastatic liver malignancies and the prognostic and therapeutic potential of SPP1.
Liu J, Yu Z, Liu Q, Dou C, Cao P, Xie X
International journal of clinical oncology 2025 May;30(5):956-973
International journal of clinical oncology 2025 May;30(5):956-973
RNA binding motif protein 25 is a negative prognostic biomarker and promotes cell proliferation via alternative splicing in hepatocellular carcinoma.
Xu K, Li W, Li X, Liu C, Yi C, Tang J, Xue F, Wang B
Pathology, research and practice 2025 May;269:155941
Pathology, research and practice 2025 May;269:155941
METTL3 enhances esophageal squamous cell carcinoma progression by suppressing ferroptosis through the PBX3/CA9 cascade.
Yang L, Ding C, Tuo M, Chu T, Liu P
Pathology, research and practice 2025 May;269:155865
Pathology, research and practice 2025 May;269:155865
Novel progressive rod-cone degeneration mutation causes retinitis pigmentosa.
Peng X, Wang X, Wang Y, Ten W, Lin Q, Zhou X
Experimental eye research 2025 May;254:110276
Experimental eye research 2025 May;254:110276
Empagliflozin attenuates renal damage in diabetic nephropathy by modulating mitochondrial quality control via Prdx3-PINK1 pathway.
Guo C, Zhang T, Du L, Yu K, Zeng S, Li M, Chi Y, Li Y
Biochemical pharmacology 2025 May;235:116821
Biochemical pharmacology 2025 May;235:116821
Adipose stem cells ameliorate erectile dysfunction in diabetes mellitus rats by attenuating ferroptosis through NRP1 with SLC7A11 interaction.
Luo JQ, Wang L, Liao ZQ, Lu BX, Luo CY, He HY, Ou Yang ZH, Duan SB, He SH, Wei AY, Zhang HB
Free radical biology & medicine 2025 May;232:40-55
Free radical biology & medicine 2025 May;232:40-55
EPIC-1042 alleviates cerebral ischemic/reperfusion injury through TAX1BP1-induced mitophagy.
Ju J, Cheng C, Cui L, Hong B, Zhan Q, Wang Q, Cui X, Su D, Huang Y, Kang C
Free radical biology & medicine 2025 May;232:367-381
Free radical biology & medicine 2025 May;232:367-381
Unveiling the Role of Oligosaccharyltransferase STT3B in Colorectal Cancer Tissues: Clinical significance and Molecular Mechanisms Driving the Formation of Tertiary Lymphoid Structures.
Zhang C, Wang B, Bian X, Zhao Y, Yang X, Zhao W
Immunobiology 2025 May;230(3):152886
Immunobiology 2025 May;230(3):152886
Breaking the synergism of iron overload and miR-122 to rescue lipid accumulation and peroxidation in MASLD.
Tang Y, Gao Z, Yang J, Li C, Wang W, Wu C, Wu M, Li M, Wu H, Sun Y, Zhang H, Chai Y, Xie F, Qian J, Shen H, Wang D
Pharmacological research 2025 May;215:107728
Pharmacological research 2025 May;215:107728
The ER protein CANX (calnexin)-mediated autophagy protects against alzheimer disease.
Shen H, Xie Y, Wang Y, Xie Y, Wang Y, Su Z, Zhao L, Yao S, Cao X, Liang J, Long J, Zhong R, Tang J, Wang S, Zhang L, Wang X, Stork B, Cui L, Wu W
Autophagy 2025 May;21(5):1096-1115
Autophagy 2025 May;21(5):1096-1115
The ROS Mediates MCUb in Mitochondria-Regulated Apoptosis of TM4 Cells Induced by Titanium Dioxide Nanoparticles.
Sun C, Wang Q, Li P, Dong R, Lei Y, Hu Y, Yan Y, Song G
Biological trace element research 2025 May;203(5):2760-2775
Biological trace element research 2025 May;203(5):2760-2775
METTL7B-induced histone lactylation prevents heart failure by ameliorating cardiac remodelling.
Chen Z, Zhong M, Lin Y, Zhang W, Zhu Y, Chen L, Huang Z, Luo K, Lu Z, Huang Z, Yan Y
Journal of molecular and cellular cardiology 2025 May;202:64-80
Journal of molecular and cellular cardiology 2025 May;202:64-80
Hydrogen sulfide improves depression-like behaviors in CUMS-induced mice by regulating autophagy.
Ling Z, Kong Q, He Z, Hao X, Liu R, Liu J, Wang Y, Liu J, Du W, Liu Y
Psychoneuroendocrinology 2025 May;175:107418
Psychoneuroendocrinology 2025 May;175:107418
Experimental Autoimmune Neuritis Nerve Demyelination Is Attenuated by Blocking JAK2/STAT3 Signaling Pathway in Rats.
Zhou R, Liu S, Liu Y, Liu Y, Fu R, Yao J, Lu Z
Brain and behavior 2025 May;15(5):e70566
Brain and behavior 2025 May;15(5):e70566
Liquiritin improves macrophage degradation of engulfed tumour cells by promoting the formation of phagolysosomes via NOX2/gp91phox.
Yang C, Chen K, Chen Y, Xie X, Li P, Zhao M, Liang J, Xie X, Chen X, Cai Y, Xu B, Wang Q, Zhou L, Luo X
Journal of pharmaceutical analysis 2025 May;15(5):101093
Journal of pharmaceutical analysis 2025 May;15(5):101093
Effective-compounds of Jinshui Huanxian Formula acts as an SRC inhibitor to inhibit HK2-mediated H3K18 lactation and improve pulmonary fibrosis.
Zheng J, Du Y, Shao W, Li J, Zhao P, Zhang Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156628
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156628
Deoxyshikonin from Arnebiae Radix promotes hair growth by targeting the Wnt/β-catenin signaling pathway.
Li Y, Mu Y, Chen X, Zhao Y, Ji C, Xu R, Jiang R, Liu F, Wang M, Sun L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156590
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156590
Apigenin ameliorates inflamed ulcerative colitis by regulating mast cell degranulation via the PAMP-MRGPRX2 feedback loop.
Huang Y, Wang N, Ji X, Luo S, Gong L, Zhao C, Zheng G, Liu R, Zhang T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156564
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156564
Procyanidins inhibit alphacoronavirus infection by reducing interferon antagonism.
Liu Y, Wang X, Wang X, Mao W, Weng Y, Zhao Y, Duan C, Wang J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156549
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156549
10-Hydroxydec-2-enoic acid reduces vascular smooth muscle cell inflammation via interacting with Toll-like receptor 4.
Jia F, Wang Y, Chen Z, Jin J, Zeng L, Zhang L, Tang H, Wang Y, Fan P
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156534
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156534
GRB2 Promotes Malignant Behaviors of Breast Cancer by Modulating the Global Expression and Alternative Splicing Profiles in SK-BR-3 Cells Through Binding mRNA.
Liu W, Huang Y, Qiao L, Chong L, Xia L, Abudurehaman A, Li H
Cancer medicine 2025 May;14(10):e70905
Cancer medicine 2025 May;14(10):e70905
The Immune Regulation of Melanin From Gallus gallus domesticus Brisson Against Cyclophosphamide-Induced Immunosuppression.
Liu J, Gao H, Liu T, Zhang T, Nan T, Li H, Li H, Li J, Yuan Y
Food science & nutrition 2025 May;13(5):e70253
Food science & nutrition 2025 May;13(5):e70253
Trehalose attenuates testicular aging by activating autophagy and improving mitochondrial quality.
Xi H, Shan W, Li M, Wang Z, Li Y
Andrology 2025 May;13(4):911-920
Andrology 2025 May;13(4):911-920
EHF promotes liver cancer progression by meditating IL-6 secretion through transcription regulation of KDM2B in TAMs.
Wei S, Zhao S, Yang W, Zhou J, Xu G, Zhang C, Wang M, Xiao H, Feng Y, Shang L, Pan C, Yu C, Chen M, Ma Y
Cellular signalling 2025 May;129:111670
Cellular signalling 2025 May;129:111670
Dectin-1 participates in neuroinflammation and dopaminergic neurodegeneration through synergistic signaling crosstalk with TLR4.
Xue F, Zhang M, Zhao RY, Wang XW, Gu Y, Yang Y, Chen WF
Brain, behavior, and immunity 2025 May;126:260-273
Brain, behavior, and immunity 2025 May;126:260-273
IFITM2 Modulates Endocytosis Maintaining Neural Stem Cells in Developing Neocortex.
Lv Y, Zou W, Li L, Zhang S, Liang J, Pu J, Jiao J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(17):e2501593
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(17):e2501593
Enhancing Prime Editing Efficiency Through Modulation of Methylation on the Newly Synthesized DNA Strand and Prolonged Expression.
Han X, Xu X, Xiong Y, Zhao G, He R, Su Y, Li S, Zhao C, Xi X, Zhao Y, Xu X, Xie S, Wang H, Li X, Zhao S, Ruan J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(17):e2417790
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(17):e2417790
Mitigating Doxorubicin-Induced Cardiotoxicity and Enhancing Anti-Tumor Efficacy with a Metformin-Integrated Self-Assembled Nanomedicine.
Huang J, Yang J, Yang Y, Lu X, Xu J, Lu S, Pan H, Zhou W, Li W, Chen S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(17):e2415227
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(17):e2415227
MARVELD1 inhibits Neuro2a cell migration and tumorigenesis via regulating the transcriptional coactivators and protein methylation.
Liu W, Dong Y, Guo R, Zhou D, Qin Y, Ma Y, Zhang J, Li A
Bulletin du cancer 2025 May;112(5):458-468
Bulletin du cancer 2025 May;112(5):458-468
Aged mice-derived bronchial epithelial cells regulate Th17 cell differentiation in asthma via the MBD2-sICOSL axis.
Chen Z, Shang Y, Yuan Y, Ji X, Gong S, Zeng Q, Xiang X
Cellular immunology 2025 May-Jun;411-412:104954
Cellular immunology 2025 May-Jun;411-412:104954
Subchondral injection of human umbilical cord mesenchymal stem cells ameliorates knee osteoarthritis by inhibiting osteoblast apoptosis and TGF-beta activity.
Wu C, Xu H, Wu Z, Huang H, Ge Q, Xu J, Chen J, Wang P, Yuan W, Jin H, Tong P
Stem cell research & therapy 2025 May 9;16(1):235
Stem cell research & therapy 2025 May 9;16(1):235
Mechanistic Insights into the Anti-Hepatocellular Carcinoma Effects of ACY-1215: p53 Acetylation and Ubiquitination Regulation.
Yin Y, Du Y, Xu Y, Zhu Z, Hu Y, Xu L, Yang K, Chen T, Shi Y, Wang C, Zhang Y
Current issues in molecular biology 2025 May 8;47(5)
Current issues in molecular biology 2025 May 8;47(5)
Metabolic-associated fatty liver disease (MAFLD) promotes the progression of hepatocellular carcinoma by enhancing KIF20A expression.
Hu X, Chen Y, Ying H, He C, Ren Y, Tian Y, Tan Y
International immunopharmacology 2025 May 8;154:114589
International immunopharmacology 2025 May 8;154:114589
GTS-21 alleviates sepsis-induced atrial fibrillation susceptibility by modulating macrophage polarization and Neuregulin-1 secretion.
Zhou J, Wu K, Ma Y, Zhu J, Zhou Y, Zhang Z, Li F, Zeng G, Li S, Tan S, Zhang Y, Wan C, Tu T, Lin Q, Liu Q
International immunopharmacology 2025 May 8;154:114561
International immunopharmacology 2025 May 8;154:114561
Immunodynamic axis of fibroblast-driven neutrophil infiltration in acute pancreatitis: NF-κB-HIF-1α-CXCL1.
Wang Q, Zhang X, Han C, Lv Z, Zheng Y, Liu X, Du Z, Liu T, Xue D, Li T, Wang L
Cellular & molecular biology letters 2025 May 7;30(1):57
Cellular & molecular biology letters 2025 May 7;30(1):57
Pterostilbene attenuates intestinal barrier damage and secondary liver oxidative stress in a murine model of Clostridium difficile infection by regulating the gut microbiota.
Yang H, Kuang Y, Wang L, Ma X, Gálvez JAV, Lu J, Dai Y, Liu S, Yao J, Chen X, Cao Y
Food & function 2025 May 6;16(9):3325-3343
Food & function 2025 May 6;16(9):3325-3343
Prostaglandin E2 receptor EP4 activation induces tolerogenic dendritic cells to mitigate ischemic acute kidney injury.
Li C, Yang C, Wang P, Wu A, Zhu J, Shi W, Zhang Y, Ma Q, Peng T, Xu J, Zhang T
Scientific reports 2025 May 31;15(1):19170
Scientific reports 2025 May 31;15(1):19170
RBAP48 facilitates the oral squamous cell carcinoma process in an androgen receptor-dependent and independent manners.
Wang X, Yan G, Li H, Wang C, Kang Y, Wang S, Liu W, Lin L, Zou R, Zeng K, Wang M, Luan R, Zhou B, Bai Y, Yang D, Ning B, Sun G, Zhao Y
Communications biology 2025 May 30;8(1):829
Communications biology 2025 May 30;8(1):829
Neutrophil Extracellular Traps Promote AIM2-Dependent Microglial Pyroptosis Following Stroke.
Chen H, Ni L, Zhang J, Zheng X, Chen Y, Jin X, Hu B, Xu X, Tang Q, Li S, Hao Y, Sun S, He C, Cao S, Hu X
Aging and disease 2025 May 30;17(3):1616-1633
Aging and disease 2025 May 30;17(3):1616-1633
Single-cell and spatial transcriptome analyses reveal tumor heterogeneity and immune remodeling involved in pituitary neuroendocrine tumor progression.
Su W, Ye Z, Liu J, Deng K, Liu J, Zhu H, Duan L, Shi C, Wang L, Zhao Y, Gong F, Zhang Y, Hou B, You H, Feng F, Ling Q, Xiao Y, Guo Y, Fan W, Zhang S, Zhang Z, Hu X, Yao Y, Zheng C, Lu L
Nature communications 2025 May 30;16(1):5007
Nature communications 2025 May 30;16(1):5007
Obacunone acts as a histone deacetylase 1 inhibitor to limit p38MAPK signaling and alleviate osteoarthritis progression.
Gao Y, Wang K, Shi C, Gao Y, Kong DQ
Journal of orthopaedic surgery and research 2025 May 3;20(1):441
Journal of orthopaedic surgery and research 2025 May 3;20(1):441
AMH regulates granulosa cell function via ESR2/ p38-MAPK signaling pathway in sheep.
Xu H, Cai Y, Yang H, Zhang C, Liu W, Zhao B, Wang F, Zhang Y
Communications biology 2025 May 29;8(1):824
Communications biology 2025 May 29;8(1):824
Multi-omics analyses, cell experiments, and network pharmacology tools identified key proteins and candidate drugs for alopecia areata treatment.
Bi L, Wang J, Yang J, Zhuang Z, Chen K, Xu Z, Zuo X, Xu J, Sheng Y, Cui Y
Clinical proteomics 2025 May 29;22(1):22
Clinical proteomics 2025 May 29;22(1):22
Metabolites from the Dendrobium Endophyte Pseudomonas protegens CM-YJ44 Alleviate Insulin Resistance in HepG2 Cells via the IRS1/PI3K/Akt/GSK3β/GLUT4 Pathway.
Qin L, Zhou Y, Fan B, Zheng J, Diao R, Liu J, Wang F
Pharmaceuticals (Basel, Switzerland) 2025 May 29;18(6)
Pharmaceuticals (Basel, Switzerland) 2025 May 29;18(6)
Enhanced SIRT1-TFEB Interaction Promotes Lysosome Biogenesis and Autophagy by Reducing TFEB Acetylation: Revealing the Enterotoxicity Disparity of Deoxynivalenol and T-2 Toxin.
Xu Q, Lin R, Jiang T, Deng L, Wu Y, Yuan Q, Qi X, Mu P, Jiang J, Deng Y, Wen J
Journal of agricultural and food chemistry 2025 May 28;73(21):12993-13005
Journal of agricultural and food chemistry 2025 May 28;73(21):12993-13005
Atractylenolide-1 Alleviates Ulcerative Colitis via Restraining RhoA/ROCK/MLC Pathway-Mediated Intestinal Barrier Dysfunction.
Gao Z, Yu X, Su W, Huang P, Li Z, Lin Y, Chen LL, Cao Y, Liu Y, Chen J, Yang D, Cao G
Journal of agricultural and food chemistry 2025 May 28;73(21):12690-12701
Journal of agricultural and food chemistry 2025 May 28;73(21):12690-12701
Ethanol extract of Moschus attenuates glutamate-induced cytotoxicity in HT22 cells by regulating the Nrf2 and MAPK pathways.
Chu Z, Chen Y, Xie D, Song C, Yang L, Qin T, Zhai Z, Cao Z, Xu Y, Sun T
Journal of ethnopharmacology 2025 May 28;348:119879
Journal of ethnopharmacology 2025 May 28;348:119879
Huatanhuoxue decoction alleviates airway inflammation by regulating IL-17A signaling pathway in obese asthmatic mice.
Sun Y, Jia Y, Yan X, Zhang Q, Li X, Yang Z, Wei D, Wu X, Mao Z, Cao X, Tong X, Huang F
Journal of ethnopharmacology 2025 May 28;348:119814
Journal of ethnopharmacology 2025 May 28;348:119814
TiO(2) Nanotube Implants Modified with Silk Fibroin and Mesoporous Silica Nanocomposite Coatings Enable Efficient Drug Release to Promote Osteogenesis.
Mu Y, Li M, Zhao X, Gong C, Luo Z, Li B, Zhang W, Ge X, Chen S, Zhou J
ACS applied materials & interfaces 2025 May 28;17(21):30600-30612
ACS applied materials & interfaces 2025 May 28;17(21):30600-30612
IGFBP5 promotes EndoMT and renal fibrosis through H3K18 lactylation in diabetic nephropathy.
Hu X, Chen W, Yang M, Li M, Li X, Ouyang S
Cellular and molecular life sciences : CMLS 2025 May 27;82(1):215
Cellular and molecular life sciences : CMLS 2025 May 27;82(1):215
Icariin alleviates cardiomyocyte pyroptosis through AMPK-NLRP3 pathway to ameliorates diabetic cardiomyopathy.
Cai Z, Sun F, Wang Q, Li S, Wang L, Li H, Su Y, Yang H, Dong B
International immunopharmacology 2025 May 27;156:114690
International immunopharmacology 2025 May 27;156:114690
Inhibition of CDK5 signaling mediated inflammation in macrophages promotes cutaneous wound healing.
Wang J, Ji L, Gao Y, Sun J, Zhou X, Ding Y, Zhou Z, Guo X, Liu C, Wang Y, Zhang Q, Lv Z, Ma D
Scientific reports 2025 May 27;15(1):18509
Scientific reports 2025 May 27;15(1):18509
Long non-coding RNA HOXA11-AS inhibits apoptosis, induces proliferation, and promotes autophagy via the miR-214-3p/ATG12 axis in acute T lymphoblastic leukemia.
Zhang R, Zhang Y, Li X, Wang S, Li J, Shao S, Liu B, Guo W, Shi M
Journal of molecular histology 2025 May 26;56(3):170
Journal of molecular histology 2025 May 26;56(3):170
Comprehensive analysis of FAM83B in pan-cancer and preliminary exploration in esophageal squamous cell carcinoma.
Guo W, Zhao X, Huang X, Zhang R, Wang Y, He X, Ma X, Hao Y, Geng S, Pan S, Ma H
Journal of molecular histology 2025 May 26;56(3):169
Journal of molecular histology 2025 May 26;56(3):169
Carboxylesterase 1 regulates peroxisome proliferator-activated receptor gamma to inhibit the growth and metastasis of breast cancer cells.
Wen J, Geng L, Wang R, Zhang X, Sui Y, Liu X, Han X
Journal of molecular histology 2025 May 26;56(3):167
Journal of molecular histology 2025 May 26;56(3):167
Macrophage Notch1 drives septic cardiac dysfunction by impairing mitophagy and promoting NLRP3 activation.
Zheng Y, Lin J, Wan G, Gu X, Ma J
Biology direct 2025 May 26;20(1):65
Biology direct 2025 May 26;20(1):65
Identification and validation of USP15 and CUL2 as ubiquitination related biomarker in chronic obstructive pulmonary disease.
Sun S, Zhang Z, Zhao H
Hereditas 2025 May 24;162(1):86
Hereditas 2025 May 24;162(1):86
MiR-493-5p functions as a tumour suppressor in head and neck squamous cell carcinoma progression by targeting HIF-1α.
Liu J, Tian R, Chen X, Song Q, Sun C, Li D, Fang Y, Lv S, Li Y, Song X
Discover oncology 2025 May 24;16(1):899
Discover oncology 2025 May 24;16(1):899
Metformin ameliorates trophoblastic immunometabolic disorders via attenuating TLR4/NF-κB signaling through ATXN7L3-mediated histone H2B monoubiquitination.
Zhang Y, Yu Z, Zhao Y, Zou L, Deng B, Liu X
Placenta 2025 May 23;165:50-61
Placenta 2025 May 23;165:50-61
Mechanical signal modulates prostate cancer immune escape by USP8-mediated ubiquitination-dependent degradation of PD-L1 and MHC-1.
Ke ZB, Chen JY, Xue YT, Lin B, Huang Q, Huang XY, Chen DN, Chen SH, Ye XJ, Zheng QS, Wei Y, Xue XY, Xu N
Cell death & disease 2025 May 23;16(1):413
Cell death & disease 2025 May 23;16(1):413
Controlled reversible methionine-selective sulfimidation of peptides.
He Z, Zhao X, Gao WY, Bao G, Li Y, Zuo Q, Song X, Mou LY, Sun W, Wang R
Science advances 2025 May 23;11(21):eadv8712
Science advances 2025 May 23;11(21):eadv8712
Immunopeptidomics-guided discovery and characterization of neoantigens for personalized cancer immunotherapy.
Cai Y, Gong M, Zeng M, Leng F, Lv D, Guo J, Wang H, Li Y, Lin Q, Jing J, Zhang Y, Xu J, Li Y
Science advances 2025 May 23;11(21):eadv6445
Science advances 2025 May 23;11(21):eadv6445
Structural Optimization of Pyrazole Compounds as Hsp90 Regulators with Enhanced Antitumor Activity.
Feng ZW, Li L, Zhang SD, Wang YJ, Pei JY, Chen NN, Wu BD, Zheng QL, You QD, Guo XK, Xu XL
Journal of medicinal chemistry 2025 May 22;68(10):9886-9905
Journal of medicinal chemistry 2025 May 22;68(10):9886-9905
Repetitive Compressive Loading Downregulates Mitochondria Function and Upregulates the Cartilage Matrix Degrading Enzyme MMP-13 Through the Coactivation of NAD-Dependent Sirtuin 1 and Runx2 in Osteoarthritic Chondrocytes.
Takemoto M, Sugishita Y, Takahashi-Suzuki Y, Fujiya H, Niki H, Yudoh K
International journal of molecular sciences 2025 May 22;26(11)
International journal of molecular sciences 2025 May 22;26(11)
Osteocyte-derived extracellular vesicles mediate the bone-to-cartilage crosstalk and promote osteoarthritis progression.
Liu N, Ma Y, Gong W, Shao X, Shi T, Li L, Wu W, Chen X, Shi Y, Zhang P, Lin J, Wang C, Fang D, Yang L, Wang P, Gao W, He Y, An X, Du R, Chen Y, Liu B, Qin J, Chen D, Cai P, Jiang Q, Guo B
Nature communications 2025 May 22;16(1):4746
Nature communications 2025 May 22;16(1):4746
Single-cell sequencing and transcriptomic data reveal that P65 activation significantly promotes microglia-mediated neuroinflammation after ischemic stroke.
Wang R, Qian Y, Zhou X, Xu H, Wang Y, Geng Y, Wang T, Sha B
Scientific reports 2025 May 22;15(1):17760
Scientific reports 2025 May 22;15(1):17760
Co-encapsulation of norcantharidin prodrugs and lomitapide in nanoparticles to regulate CCL4 expression by inhibiting Wnt/β-catenin pathway for improved anti-tumor immunotherapy.
Zhao F, Gong L, Wang P, Chen D, Cao S, Yang F, Tang M, Meng Y, Wang Y, Miao L, Li Y, Huang W
Journal of nanobiotechnology 2025 May 21;23(1):369
Journal of nanobiotechnology 2025 May 21;23(1):369
Iron Replacement Attenuates Hypoxic Pulmonary Hypertension by Remodeling Energy Metabolism via Regulating the HIF2α/Mitochondrial Complex I, III/ROS Axis.
Geng Y, Wang H, Bai Z, Ge R
Biomolecules 2025 May 21;15(5)
Biomolecules 2025 May 21;15(5)
miR-139-5p activates ferroptosis by inhibiting the expression of HMG-CoA reductase to inhibit the progression of glioma.
You Z, Wu F, Zheng Y, Yang H, Ye J, Cai H, Luo C, Liu Y, Ke Y, Xu X
Cell death discovery 2025 May 21;11(1):245
Cell death discovery 2025 May 21;11(1):245
A dual-targeting bio-liposomes nanodrug repair endothelial cell dysfunction and restore macrophage cholesterol flow homeostasis to treat early atherosclerosis.
Zhang Q, Ma S, Kang X, Liu Y, Ma F, Yu F, Luo X, Li G, Hao Y, Zhang H, Liu B, Jiang Y
Journal of nanobiotechnology 2025 May 20;23(1):365
Journal of nanobiotechnology 2025 May 20;23(1):365
LONP1 facilitates pulmonary artery smooth muscle cell glycolytic reprogramming by degrading MPC1 in pulmonary hypertension.
Li M, Zhang W, Zhang M, Li L, Yao Y, Qin Y, Wang D, Yan G, Qiao Y, Tang C
Clinical science (London, England : 1979) 2025 May 20;139(10):479-501
Clinical science (London, England : 1979) 2025 May 20;139(10):479-501
SIRT2 inhibition enhances mitochondrial apoptosis in Brucella-infected bovine placental trophoblast cells.
Zhang M, Qi L, Li J, Yuan N, Zhai Y, Hao M, Zhou D, Liu W, Jin Y, Wang A
Veterinary research 2025 May 2;56(1):97
Veterinary research 2025 May 2;56(1):97
USP14 inhibits mitophagy and promotes tumorigenesis and chemosensitivity through deubiquitinating BAG4 in microsatellite instability-high colorectal cancer.
Wang Z, Yu C, Xie G, Tao K, Yin Z, Lv Q
Molecular medicine (Cambridge, Mass.) 2025 May 2;31(1):163
Molecular medicine (Cambridge, Mass.) 2025 May 2;31(1):163
Retroviral foamy virus gag induces parkin-dependent mitophagy.
Wang S, Du T, Yan J, Zheng Y, Tang Y, Wu J, Xu Q, Xu S, Liu L, Chen X, Han S, Yin J, Peng B, He X, Liu W
Retrovirology 2025 May 2;22(1):7
Retrovirology 2025 May 2;22(1):7
DNA dioxygenase TET2 deficiency aggravates sepsis-induced acute lung injury by targeting ITGA10 via the PI3K/AKT signaling pathway.
Fu H, Gao B, Zhou X, Hao Y, Liu C, Lan A, Tang J, Zhou F
Cellular & molecular biology letters 2025 May 19;30(1):60
Cellular & molecular biology letters 2025 May 19;30(1):60
Identification and verification of a polyamine metabolism-related gene signature for predicting prognosis and immune infiltration in osteosarcoma.
Qiu S, Tan C, Cheng D, Yang Q
Journal of orthopaedic surgery and research 2025 May 18;20(1):482
Journal of orthopaedic surgery and research 2025 May 18;20(1):482
Gut microbial conversion of dietary elderberry extract to hydrocinnamic acid improves obesity-associated metabolic disorders.
Alqudah S, DeLucia B, Osborn LJ, Markley RL, Bobba V, Preston SM, Thambidurai T, Nia LH, Fulmer CG, Sangwan N, Nemet I, Claesen J
bioRxiv : the preprint server for biology 2025 May 18;
bioRxiv : the preprint server for biology 2025 May 18;
Tong-Qiao-Huo-Xue Decoction mitigates post-stroke inflammatory response via suppression of the FIB-NLRP3 signaling pathway.
Huang P, Sun H, Wang Y, Wang N
Metabolic brain disease 2025 May 17;40(5):206
Metabolic brain disease 2025 May 17;40(5):206
ClC-3-depedent polarization of microglia protects against cerebral ischemic injury in mice.
Wang MQ, Wang B, Yang X, Zhang QC, Wang XY, Dong YF
International immunopharmacology 2025 May 16;155:114618
International immunopharmacology 2025 May 16;155:114618
Inhibition of diacylglycerol O-acyltransferase 1 provides neuroprotection by inhibiting ferroptosis in ischemic stroke.
Zeng Y, Guo R, Chen S, Lin Y, Cao S, Wang X, Zhang S, Xu H, Qing W, Yang H, Ouyang W
Molecular medicine (Cambridge, Mass.) 2025 May 15;31(1):191
Molecular medicine (Cambridge, Mass.) 2025 May 15;31(1):191
Comprehensive bioinformatics analysis of MEX3 family genes in hepatocellular carcinoma.
Zhang X, Sun P, Chu T, Feng Y, Zhang X
Scientific reports 2025 May 15;15(1):16971
Scientific reports 2025 May 15;15(1):16971
miR-370-3p Inhibited the Proliferation of Sheep Dermal Papilla Cells by Inhibiting the Expression of SMAD4.
Fu J, Wang D, Liu W, Qi Y, Zhang C, Li H, Cai J, Ji S, Zhang L, Sun F
Cells 2025 May 14;14(10)
Cells 2025 May 14;14(10)
Network pharmacology and experimental verification to explore the molecular mechanisms of Astragaloside IV against diabetic encephalopathy.
Wang Y, Yang Q, Lu Y, Jiang L, Zhang R, Jiang S, Xu Y, Xu S, Geng Z
Biochemical and biophysical research communications 2025 May 12;763:151778
Biochemical and biophysical research communications 2025 May 12;763:151778
Copper's new role in cancer: how cuproptosis-related genes could revolutionize glioma treatment.
Wang Y, Qiao S, Wang P, Li M, Ma X, Wang H, Dong J
BMC cancer 2025 May 12;25(1):859
BMC cancer 2025 May 12;25(1):859
A Novel Hybrid Peptide VLP-Aβ Exhibits Antioxidant Activity In Vitro and In Vivo via KEAP1-NRF2-ARE Signaling Pathway.
Wang J, Zhang W, Zhang R, Zhao X, Zhang J, Zhou Y, Tong Y, Abbas Z, Li Z, Zhang H, Yang D, Chen S, Hu C, Si D, Wei X
Antioxidants (Basel, Switzerland) 2025 May 12;14(5)
Antioxidants (Basel, Switzerland) 2025 May 12;14(5)
Multiomics analysis revealed the effects of polystyrene nanoplastics at different environmentally relevant concentrations on intestinal homeostasis.
Yang JZ, Li JH, Liu JL, Zhou AD, Wang H, Xie XL, Zhang KK, Wang Q
Environmental pollution (Barking, Essex : 1987) 2025 May 1;372:126050
Environmental pollution (Barking, Essex : 1987) 2025 May 1;372:126050
SNORD9 promotes ovarian cancer tumorigenesis via METTL3/IGF2BP2-mediated NFYA m6A modification and is a potential target for antisense oligonucleotide therapy.
Chen S, Wen JT, Zhang S, Wang JL, Yuan J, Bao HJ, Chen X, Zhao Y
Life sciences 2025 May 1;368:123527
Life sciences 2025 May 1;368:123527
Inhibition of microRNA-139-5p by glucagon-like peptide-1 ameliorates oxidative stress-induced vascular endothelial cell damage via targeting SOD1/GCLc.
Zhang J, Mo J, Liu Y, Meng X, Tang W, Fu L, Xiong J, Mo Z
Endocrine connections 2025 May 1;14(5)
Endocrine connections 2025 May 1;14(5)
SIRT1 Alleviates Mitochondrial Fission and Necroptosis in Cerebral Ischemia/Reperfusion Injury via SIRT1-RIP1 Signaling Pathway.
Wei X, Guo H, Huang G, Luo H, Gong L, Meng P, Liu J, Zhang W, Mei Z
MedComm 2025 Mar;6(3):e70118
MedComm 2025 Mar;6(3):e70118
FABP3 promotes cell apoptosis and oxidative stress by regulating ferroptosis in lens epithelial cells.
Wang Q, Zhang C, Yu B, Zhang Y, Guo Y
Free radical research 2025 Mar;59(3):250-261
Free radical research 2025 Mar;59(3):250-261
Curcumin attenuates myocardial ischemia‑reperfusion‑induced autophagy‑dependent ferroptosis via Sirt1/AKT/FoxO3a signaling.
Zhao ST, Qiu ZC, Xu ZQ, Tao ED, Qiu RB, Peng HZ, Zhou LF, Zeng RY, Lai SQ, Wan L
International journal of molecular medicine 2025 Mar;55(3)
International journal of molecular medicine 2025 Mar;55(3)
Cellular heterogeneity and communication networks in gastric cancer: Single-cell analysis reveals β-hydroxybutyrylation-associated genes and immune infiltration characteristics.
Hu Y, Xu J, Lv J, Qin Y, Lu Y, Cen F, Yang H, Chen K, Xia S
Translational oncology 2025 Mar;53:102270
Translational oncology 2025 Mar;53:102270
Inhibition of the cGAS‑STING Pathway Reduces Cisplatin-Induced Inner Ear Hair Cell Damage.
Sun Y, Zou S, Xu X, Xu S, Sun H, Tang M, Kong W, Chen X, He Z
Neuroscience bulletin 2025 Mar;41(3):359-373
Neuroscience bulletin 2025 Mar;41(3):359-373
Exploring the Role of Gut Vascular Barrier Proteins in HIV-Induced Mucosal Damage: A Comparative Study.
Jin L, Hu R, Qing Y, Rang Z, Cui F
AIDS research and human retroviruses 2025 Mar;41(3):159-166
AIDS research and human retroviruses 2025 Mar;41(3):159-166
Astragaloside IV Relieves Central Sensitization by Regulating Astrocytic ROS/NF-κB Nuclear Translocation Signaling in Chronic Migraine Male Rats.
Zhang W, Yang Y, Zhang X, Zhao L, Zhou J, Ji L, Chen L
Phytotherapy research : PTR 2025 Mar;39(3):1438-1452
Phytotherapy research : PTR 2025 Mar;39(3):1438-1452
Aloe-Emodin Improves Mitophagy in Alzheimer's Disease via Activating the AMPK/PGC-1α/SIRT3 Signaling Pathway.
Wang Y, Ge Y, Hua S, Shen C, Cai B, Zhao H
CNS neuroscience & therapeutics 2025 Mar;31(3):e70346
CNS neuroscience & therapeutics 2025 Mar;31(3):e70346
DNLA Delayed the Appearance of Learning and Memory Impairment of APP/PS1 Mice: Involvement of mTOR/TFEB/v-ATPase Signaling Pathway.
Wu Y, Liu X, Luo G, Li Q, Guo B, Li L, Nie J
CNS neuroscience & therapeutics 2025 Mar;31(3):e70300
CNS neuroscience & therapeutics 2025 Mar;31(3):e70300
NGR1 reduces neuronal apoptosis through regulation of ITGA11 following subarachnoid hemorrhage.
Hou Y, Zhang L, Ma W, Jiang Y
Molecular medicine reports 2025 Mar;31(3)
Molecular medicine reports 2025 Mar;31(3)
SIRT5 desuccinylating IDH2 to alleviate oxidative stress in bovine mammary epithelial cells induced by ammonia.
Gao S, Yang H, Dong J, Li A, Zhang X, Liu L, Lu G, Liu Y, Zha G, Zhong K, Li H, Wang Y, Guo S
International journal of biological macromolecules 2025 Mar;295:139619
International journal of biological macromolecules 2025 Mar;295:139619
A glucomannan from defatted Ganoderma lucidum spores: structural characterization and immunomodulatory activity via activating TLR4/MyD88/NF-κB signaling pathway.
Huang J, Su Y, Wang Q, Feng M, Zhang D, Yu Q, Yan C
International journal of biological macromolecules 2025 Mar;294:139195
International journal of biological macromolecules 2025 Mar;294:139195
Adiponectin facilitates the cell cycle, inhibits cell apoptosis and induces temozolomide resistance in glioblastoma via the Akt/mTOR pathway.
Sun P, Liu F, Huo K, Wang J, Cheng Y, Shang S, Ma W, Yu J, Han J
Oncology letters 2025 Mar;29(3):127
Oncology letters 2025 Mar;29(3):127
Exercise Training After Myocardial Infarction Enhances Endothelial Progenitor Cells Function via NRG-1 Signaling.
Huang H, Huang G, Li R, Wei L, Yuan Z, Huang W
Cardiovascular toxicology 2025 Mar;25(3):411-426
Cardiovascular toxicology 2025 Mar;25(3):411-426
Anti-inflammatory Fatty Acid Derivatives From Mangrove-derived Actinomycetes Streptomyces sp.
Ge C, Xu H, Zhang XY, Wu GX, Yang M, Gu YQ, Li JL
Chemistry & biodiversity 2025 Mar;22(3):e202401946
Chemistry & biodiversity 2025 Mar;22(3):e202401946
Metformin delays the decline in thermogenic function of brown adipose tissue in a mouse model of Hutchinson-Gilford progeria syndrome.
Xiang X, Feng Y, Li H, Li W, Li J, Xia Z, Pang H, Wang Z
Experimental gerontology 2025 Mar;201:112702
Experimental gerontology 2025 Mar;201:112702
SERCA2 dysfunction accelerates angiotensin II-induced aortic aneurysm and atherosclerosis by induction of oxidative stress in aortic smooth muscle cells.
Wang L, Song J, Yang Z, Zhang H, Wang Y, Liu J, Wang S, Shi J, Tong X
Journal of molecular and cellular cardiology 2025 Mar;200:68-81
Journal of molecular and cellular cardiology 2025 Mar;200:68-81
The Effects of different forms of exercise during the early life on the bone microstructure of ovariectomized mice.
Wang Y, Zhang K, Gao W, Lin H, Li T, Liu TCY, Weng X, Yuan Y
Bone 2025 Mar;192:117364
Bone 2025 Mar;192:117364
GPSM1 interacts and cooperates with MMP19 to promote proliferation and EMT in colorectal cancer cells.
Wang L, Li N, Chen Y, Qiao Y, Song Y, Zhang X, Zhao H, Ran W, Li G, Xing X
Biochimica et biophysica acta. Molecular cell research 2025 Mar;1872(3):119903
Biochimica et biophysica acta. Molecular cell research 2025 Mar;1872(3):119903
Early intervention with pericyte Fli-1 post-TBI attenuates hippocampal BBB disruption and subsequent neuroinflammation with neurological deficits.
Li J, Du M, Dong G, Hu D, Zhang H, Yu Z, Lu Y, Yang Y
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167671
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167671
1-benzyl-6-nitro-4-phenyl-4-(methoxycarbonyl)-2(1H)-pyridinone, a novel pirfenidone derivative, alleviate hepatic fibrosis through T cells.
Hu MX, Li JQ, Zhang HW, Ma YK, Zhao BJ, Xiao L, Liang W, Wang Y, Wang C, Wu CG, Liu TT
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Mar;184:117907
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Mar;184:117907
Vagus nerve stimulation inhibits PANoptosis and promotes neurofunctional recovery of cerebral ischemic stroke in a Sirt1-dependent manner.
Tang H, Wen J, Wang L, Yang Q, Qin T, Ren Y, Zhao Y, Li C, Li J, Cao H, Xu J, Yang Q
Neurochemistry international 2025 Mar;184:105950
Neurochemistry international 2025 Mar;184:105950
Concoctive principles of detoxification and retention of the main toxicity of Tripterygium wilfordii and its anti-inflammatory efficacy by concocting with the medicinal excipient Spatholobi Caulis juice.
Ji L, Zhang Y, Li Y, Song L, Zhang T, Du C, Li W, Wu X, He Q, Wang Y, Wang Q, Wang J
Fitoterapia 2025 Mar;181:106400
Fitoterapia 2025 Mar;181:106400
Zhuyu pill attenuates metabolic-associated fatty liver disease by regulating macrophage polarization through TLR4 signaling pathway.
Zhao M, He Q, Shu X, Xu R, Zhang Z, Mou Y, Liao W, Zhang Y, Zhou Z, Shen T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Mar;138:156439
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Mar;138:156439
Targeting the NF-κB p65-MMP28 axis: Wogonoside as a novel therapeutic agent for attenuating podocyte injury in diabetic nephropathy.
Li X, Zhao S, Xie J, Li M, Tong S, Ma J, Yang R, Zhao Q, Zhang J, Xu A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Mar;138:156406
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Mar;138:156406
ANXA2 promotes chondrocyte differentiation and fracture healing by regulating the phosphorylation of STAT3 and PI3K/AKT signaling pathways.
Wang X, Dong W, Wang X, Wang J
Cellular signalling 2025 Mar;127:111617
Cellular signalling 2025 Mar;127:111617
Disulfiram/Cu targeting FOXO6 modulates sensitivity of hepatocellular carcinoma to lenvatinib via disrupt choline metabolic.
Wu S, Weng J, Pan Y, Wen Z, Zeng J, Lou Y, Tong S, Liao P, Li N, Yu Z, Xia J
Cellular signalling 2025 Mar;127:111563
Cellular signalling 2025 Mar;127:111563
FABP4 Mediates Inflammation to Regulate Endometrial Epithelial Cell Function During Early Gestation in Sheep.
Chen Y, Liu C, Liu Z, Yu H, Peng X, Wang J, Hu G
Veterinary medicine and science 2025 Mar;11(2):e70193
Veterinary medicine and science 2025 Mar;11(2):e70193
Antagonizing Il10 and Il4 signaling via intracerebral decoy receptor expression attenuates Aβ accumulation.
Koller EJ, McFarland KN, Angelle C, Howard J, Ryu D, Dillon KD, Erquizi A, Beheray M, De La Cruz EG, Cruz PE, Lewis J, Golde TE, Levites Y, Chakrabarty P
Acta neuropathologica communications 2025 Mar 7;13(1):51
Acta neuropathologica communications 2025 Mar 7;13(1):51
The RNA-binding protein LARP6 regulates the alternative splicing of related genes in MDA-MB-231 cells.
Guo L, Liu Y, Yan S, Li H, Zhang K, Li J
Scientific reports 2025 Mar 6;15(1):7883
Scientific reports 2025 Mar 6;15(1):7883
Reticulophagy promotes EMT-induced fibrosis in offspring's lung tissue after maternal exposure to carbon black nanoparticles during gestation by a m(5)C-dependent manner.
Du Z, Liu Q, Wang M, Gao Y, Li Q, Yang Y, Lu T, Bao L, Pang Y, Wang H, Niu Y, Zhang R
Journal of hazardous materials 2025 Mar 5;485:136873
Journal of hazardous materials 2025 Mar 5;485:136873
TRAF1 promotes osteoclastogenesis by enhancing metabolic adaptation to oxidative phosphorylation in an AKT-dependent manner.
Kang H, Peng R, Dong Y, Liao F, Zhu M, Wang P, Hu SA, Hu P, Wang J, Liu Z, Song K, Li F
Molecular therapy : the journal of the American Society of Gene Therapy 2025 Mar 5;33(3):933-949
Molecular therapy : the journal of the American Society of Gene Therapy 2025 Mar 5;33(3):933-949
CD47 Contributes to the Proliferation of Breast Cancer.
Wang J, Wu X, Liu X, Xu Y
Frontiers in bioscience (Landmark edition) 2025 Mar 5;30(3):28210
Frontiers in bioscience (Landmark edition) 2025 Mar 5;30(3):28210
Dual GLP-1 and GIP Agonist Tirzepatide Exerted Neuroprotective Action in a Parkinson's Disease Rat Model.
Delvadia P, Dhote V, Mandloi AS, Soni R, Shah J
ACS chemical neuroscience 2025 Mar 5;16(5):818-825
ACS chemical neuroscience 2025 Mar 5;16(5):818-825
Inhibition of NLRP3 alleviates calcium oxalate crystal-induced renal fibrosis and crystal adhesion.
Xu Y, Li G, Liu W, Ge D, Hao Z, Wang W
Urolithiasis 2025 Mar 4;53(1):44
Urolithiasis 2025 Mar 4;53(1):44
VHL ameliorates arecoline-induced oral submucosal fibrosis by promoting HDAC6 ubiquitination and blocking NF-κB pathway.
Sun H, Yang C, Yin X, Chen S, Huang Y, Kuang H, Luo W
Scientific reports 2025 Mar 4;15(1):7563
Scientific reports 2025 Mar 4;15(1):7563
Human Cytomegalovirus Infection Reduces an Endogenous Antiviral Fatty Acid by Promoting Host Metabolism.
Xi Y, Mokry RL, Armas ND, Kline I, Wegner M, Purdy JG
bioRxiv : the preprint server for biology 2025 Mar 31;
bioRxiv : the preprint server for biology 2025 Mar 31;
Klotho alleviates oxidative stress and mitochondrial dysfunction through the Nrf2/HO-1 pathway, thereby reducing renal senescence induced by calcium oxalate crystals.
Xu Y, You J, Yao J, Hou B, Wang W, Hao Z
Urolithiasis 2025 Mar 29;53(1):61
Urolithiasis 2025 Mar 29;53(1):61
Yinchenhao decoction alleviates obstructive jaundice liver injury by modulating epidermal growth factor receptor and constitutive androstane receptor signaling.
Liu JJ, Mei HW, Jing YY, Li ZL, Wu SG, Yuan HX, Zhang XB
World journal of hepatology 2025 Mar 27;17(3):101724
World journal of hepatology 2025 Mar 27;17(3):101724
The Frmpd3 Protein Regulates Susceptibility to Epilepsy by Combining with GRIP and GluA2.
Jia Y, Zhan J, Huang P, Li X, Hong D, Lu X
Current issues in molecular biology 2025 Mar 26;47(4)
Current issues in molecular biology 2025 Mar 26;47(4)
Reprogramming Macrophage Phenotype Using a Reactive Oxygen Species-Responsive Liposome Delivery System for Inflammation Microenvironment Remodeling and Osteoarthritis Treatment.
Lai P, Ma Y, Sang W, Zhou Q, Chen H, Wang C, Yin J, Wang T, Zhu L, Zhou X, He C, Ma J
ACS applied materials & interfaces 2025 Mar 26;17(12):17932-17947
ACS applied materials & interfaces 2025 Mar 26;17(12):17932-17947
Apabetalone alleviates ligature-induced periodontitis by inhibiting M1 macrophage polarization via an immunometabolic shift.
Bian T, Li H, Liu H, Guo M, Zhang Y, Hu P, Chen M
International immunopharmacology 2025 Mar 26;150:114279
International immunopharmacology 2025 Mar 26;150:114279
Umbelliferone attenuates calcium oxalate crystal-induced renal injury and inflammation by attenuating autophagy through the PI3K/AKT pathway.
Xu Y, Liang H, Xia K, Yao J, Chen Y, Hou B, Hao Z
International immunopharmacology 2025 Mar 26;150:114250
International immunopharmacology 2025 Mar 26;150:114250
Circ_RUSC2 Sequesters miR-661 and Elevates TUSC2 Expression to Suppress Colorectal Cancer Progression.
Shi Y, Li D, Xu Y, Guo Y, Mao J, Lu Y
International journal of molecular sciences 2025 Mar 24;26(7)
International journal of molecular sciences 2025 Mar 24;26(7)
Protective Effects of a Polyherbal Mixture on Intestinal Injury via the NF-κB Signaling Pathway and Gut Microbiota Modulation in Hyperuricemic Mice.
Wang H, Xi Y, Gu F, Peng L, Li J
Foods (Basel, Switzerland) 2025 Mar 24;14(7)
Foods (Basel, Switzerland) 2025 Mar 24;14(7)
ZDHHC9-mediated CD38 palmitoylation stabilizes CD38 expression and promotes pancreatic cancer growth.
Guo H, Lin Z, Zhang D, Qin Q, Li Z, Yin Y, Chen J, Guo W
Communications biology 2025 Mar 22;8(1):477
Communications biology 2025 Mar 22;8(1):477
Deletion of ENO1 sensitizes pancreatic cancer cells to gemcitabine via MYC/RRM1-mediated glycolysis.
Lu Y, Ma H, Xiong X, Du Y, Liu L, Wang J, Zhao W
Scientific reports 2025 Mar 22;15(1):9941
Scientific reports 2025 Mar 22;15(1):9941
Seminal plasma proteomics of asymptomatic COVID-19 patients reveals disruption of male reproductive function.
Huang J, Su Y, Wang J, Fang Z, Zhang Y, Chen H, Wan X, Xiong Y, Song N, Chen H, Wu X
BMC genomics 2025 Mar 21;26(1):281
BMC genomics 2025 Mar 21;26(1):281
miRNA let-7f-5p-encapsulated labial gland MSC-derived EVs ameliorate experimental Sjögren's syndrome by suppressing Th17 cells via targeting RORC/IL-17A signaling axis.
Xie Y, Chai M, Xing Y, Zhou P, Wei P, Hua H
Journal of nanobiotechnology 2025 Mar 20;23(1):228
Journal of nanobiotechnology 2025 Mar 20;23(1):228
IFI16 recruits HDAC1 and HDAC2 to deacetylate the Kaposi's sarcoma-associated herpesvirus (KSHV) latency-associated nuclear antigen (LANA), facilitating latency.
Ghosh A, Britto J, Chandran B, Roy A
Journal of virology 2025 Mar 18;99(3):e0154924
Journal of virology 2025 Mar 18;99(3):e0154924
MiR-222-3p loaded stem cell nanovesicles repair myocardial ischemia damage via inhibiting mitochondrial oxidative stress.
Liu M, Wang L, Liu Z, Liu D, Li T, Ding L, Zeng S, Wang Z, Wang J, Zhang F, Zhang J, Zhang L, Li M, Liu G, Wang X, Zheng M
Life sciences 2025 Mar 15;365:123447
Life sciences 2025 Mar 15;365:123447
A New Human SCARB2 Knock-In Mouse Model for Studying Coxsackievirus A16 and Its Neurotoxicity.
Wu H, Wang Z, Zhang Y, Hu L, Yang J, Zhang C, Lou M, Pi N, Wang Q, Fan S, Huang Z
Viruses 2025 Mar 14;17(3)
Viruses 2025 Mar 14;17(3)
Oleanolic Acid Alleviates Hyperuricemia via Gut Microbiota Control the Integrity of Gut Barrier and the Expressions of Urate Transporter in Mice.
Zhang T, Liu S, Liu S, Zhao P, Zhang C, Wang X, Meng Y, Lu Y
Journal of agricultural and food chemistry 2025 Mar 12;73(10):5899-5914
Journal of agricultural and food chemistry 2025 Mar 12;73(10):5899-5914
Microneedles Loaded with Nitric-Oxide Driven Nanomotors Improve Force-Induced Efferocytosis Impairment and Sterile Inflammation by Revitalizing Macrophage Energy Metabolism.
Tan H, Wang S, He X, Yang G, Zhu Y, Yang S, Yan S, Gong C, Bai W, Hu Y, Song J, Zheng L
ACS nano 2025 Mar 11;19(9):9390-9411
ACS nano 2025 Mar 11;19(9):9390-9411
Platelet hitchhiking vascular-disrupting agents for self-amplified tumor-targeting therapy.
Chu H, Xu Y, Shan Y, Sun M, Zhao W, Fang X, Shen N, Tang Z
Journal of nanobiotechnology 2025 Mar 10;23(1):197
Journal of nanobiotechnology 2025 Mar 10;23(1):197
Correlation of IGF2 levels with sperm quality, inflammation, and DNA damage in infertile patients.
Wu JG, Zhou CP, Gui WW, Liang ZY, Zhang FB, Fu YG, Li R, Wu F, Lin XH
Asian journal of andrology 2025 Mar 1;27(2):204-210
Asian journal of andrology 2025 Mar 1;27(2):204-210
Intranasal oxytocin alleviates postsurgical pain and comorbid anxiety in mice: Participation of BK(Ca) channels in the hippocampus.
Tang YB, Tang L, Chen B, Fan MJ, Chen GJ, Ou YN, Yang F, Wu XZ
Neuropharmacology 2025 Mar 1;265:110243
Neuropharmacology 2025 Mar 1;265:110243
Bronchopulmonary dysplasia demonstrates dysregulated autotaxin/lysophosphatidic acid signaling in a neonatal mouse model.
Ha AW, Sudhadevi T, Jafri A, Mayer C, MacFarlane PM, Natarajan V, Harijith A
Pediatric research 2025 Jun;97(7):2462-2474
Pediatric research 2025 Jun;97(7):2462-2474
Topical transdermal administration of lenalidomide nanosuspensions-based hydrogels against melanoma: In vitro and in vivo studies.
Zhang M, Qiu H, Han Z, Ma Y, Hou J, Yuan J, Jia H, Zhou M, Lu H, Wu Y
International journal of pharmaceutics: X 2025 Jun;9:100316
International journal of pharmaceutics: X 2025 Jun;9:100316
Gastrodin Alleviates Lumbar Intervertebral Disc Degeneration by Suppressing the NF-κB and MAPK Pathways.
Hu H, Xie T
Cell biochemistry and biophysics 2025 Jun;83(2):2009-2021
Cell biochemistry and biophysics 2025 Jun;83(2):2009-2021
USP5 Stabilizes IKBKG Through Deubiquitination to Suppress Ferroptosis and Promote Growth in Non-small Cell Lung Cancer.
Li Y, Qiu G, Zhou M, Chen Q, Liao X
Cell biochemistry and biophysics 2025 Jun;83(2):1645-1656
Cell biochemistry and biophysics 2025 Jun;83(2):1645-1656
GLA deficiency causes cardiac hypertrophy via enhanced autophagy.
Ou W, Li X, Tang K, Ding L, Sun T, Li Q, Li T
Science China. Life sciences 2025 Jun;68(6):1689-1702
Science China. Life sciences 2025 Jun;68(6):1689-1702
Inhibition Peroxiredoxin-2 by Capsaicin Ameliorates Rheumatoid Arthritis via ROS-Mediated Apoptosis in Fibroblast-Like Synoviocytes.
He H, Hao M, Luo P, Chen J, An Y, Huang J, He R, Du Q, Zhang Q, Wang J
MedComm 2025 Jun;6(6):e70209
MedComm 2025 Jun;6(6):e70209
Copper oxide nanoparticles induce pulmonary inflammation via triggering cellular cuproptosis.
Zhang X, Peng Z, Wang Q, Zhang W, Bu Q, Sun D
Toxicology 2025 Jun;514:154131
Toxicology 2025 Jun;514:154131
H3K18 lactylation-mediated SIX1 upregulation contributes to silica-induced epithelial-mesenchymal transition in airway epithelial cells.
Liu S, He Y, Jin L, Shi S, Zhang J, Xie W, Yang M, Zhang Q, Kong H
Toxicology 2025 Jun;514:154109
Toxicology 2025 Jun;514:154109
Intervention and mechanism of Xiaoyin Anshen Yin in treatment of psoriasis combined with sleep disorders.
Ruohan D, Xingwu D, Lingling LI, Tiange QU, Huishang F, Guangshan C
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2025 Jun;45(3):552-560
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2025 Jun;45(3):552-560
LRRK2 reduces the sensitivity to TKI and PD-1 blockade in ccRCC via activating LPCAT1.
Hong Y, Li W, Xing Z, Lu M, Tang T, Zhu L, Xiong W, Zhang H, Liu W, Ren S
Oncogene 2025 Jun;44(22):1761-1776
Oncogene 2025 Jun;44(22):1761-1776
Exosomal miR-196a-5p Secreted by Bone Marrow Mesenchymal Stem Cells Inhibits Ferroptosis and Promotes Drug Resistance of Acute Myeloid Leukemia.
Fan B, Wang L, Hu T, Zheng L, Wang J
Antioxidants & redox signaling 2025 Jun;42(16-18):933-953
Antioxidants & redox signaling 2025 Jun;42(16-18):933-953
Astaxanthin Alleviates Lung Injury by Regulating Oxidative Stress, Inflammatory Response, P2X7 Receptor, NF-κB, Bcl-2, and Caspase-3 in LPS-Induced Endotoxemia.
Ozkanlar S, Ozkanlar Y, Kara A, Dalkilinc E
Environmental toxicology 2025 Jun;40(6):924-934
Environmental toxicology 2025 Jun;40(6):924-934
Membrane biomimetic nanoenzyme-incorporated hybrid glycyrrhizic acid hydrogel for precise mitochondrial ROS scavenging for osteoarthritis treatment.
Fan Y, Niu Z, Yin L, Yao L, Ding S, Tong Y, Wang J, Hong Z, Chen J, Zhang Q, Ji L, Chen J, Xia C, Bi Q
Materials today. Bio 2025 Jun;32:101778
Materials today. Bio 2025 Jun;32:101778
Endoscopic nasal delivery of engineered endothelial progenitor cell-derived exosomes improves angiogenesis and neurological deficits in rats with intracerebral hemorrhage.
Wan G, Li Z, Gu L, Sun Y, Wang Y, Wang Y, Geng R, Chen Y, Ma W, Bao X, Wang R
Materials today. Bio 2025 Jun;32:101652
Materials today. Bio 2025 Jun;32:101652
A pectic polysaccharide from wax gourd peel improves ethanol-induced gastric ulcer injury in mice via the PI3K/AKT signaling pathway.
Luo B, Cai M, Huang H, Zhang Y, Chen P, Ji R, Wang F, Liao P, Xian M
International journal of biological macromolecules 2025 Jun;316(Pt 2):144755
International journal of biological macromolecules 2025 Jun;316(Pt 2):144755
Environmental responsive dual-drug synergistic and dual-targeted polymer micelles based on chondroitin sulfate for treatment of breast cancer.
Hu L, Ma H, Yang C, Wang K, Ji X, Xu T, Xu H, Zhao Y, Zhen Y
International journal of biological macromolecules 2025 Jun;311(Pt 4):144083
International journal of biological macromolecules 2025 Jun;311(Pt 4):144083
Downregulation of forkhead box O1 (FOXO1) acetylation ameliorates cognitive dysfunction by inhibiting endoplasmic reticulum stress-regulated neuronal apoptosis in APP/PS1 transgenic mice.
Zhang N, Zhao Z, Chen X, Yao H, Zhu M, Ma S, Wang H, Yin X, Zhou Y, Zheng C, Li J, Pan J, Wang K, Yang B, Wang Y, Fan J, Gong Y, Liu R, Zeng J, Fan X, Shentu Y
Neuroprotection (Chichester, England) 2025 Jun;3(2):183-201
Neuroprotection (Chichester, England) 2025 Jun;3(2):183-201
Mechanistic study of Liquiritigenin inhibiting bladder cancer cell proliferation and migration by regulating STING1.
Li W, Yin Q, Qiu Y, Liu J, Wang J, Li C, Zhang D, Zhang P, Lv H, Lv Y, Wang Y
Cancer genetics 2025 Jun;294-295:156-170
Cancer genetics 2025 Jun;294-295:156-170
Human transmembrane protein 68 links triacylglycerol synthesis to membrane lipid homeostasis.
Zeng F, Heier C, Yu Q, Pang H, Huang F, Zhao Z, Chang P
The FEBS journal 2025 Jun;292(11):2935-2952
The FEBS journal 2025 Jun;292(11):2935-2952
Comprehensive analysis indicates DDX46 as a novel biomarker for the prognosis of lung adenocarcinoma.
Bian T, Zheng M, Wang T, Zhang Q, Zhang J, Liu Y, Shi W
Oncology letters 2025 Jun;29(6):292
Oncology letters 2025 Jun;29(6):292
Monoclonal Antibodies to Thyrotropin Receptor With Thyroid-Stimulating Activity Activate the NF-κB Pathway to Induce Chemokine Expression.
Yang Y, Hui C
Journal of cellular and molecular medicine 2025 Jun;29(11):e70647
Journal of cellular and molecular medicine 2025 Jun;29(11):e70647
MiR214-3p Ameliorates Diabetic Cardiomyopathy by Inhibiting Ferroptosis.
Chen P, Huang X, Wen W, Cao Y, Li W, Huang G, Huang Y, Hu Y, Ma T
Cardiovascular toxicology 2025 Jun;25(6):884-897
Cardiovascular toxicology 2025 Jun;25(6):884-897
Senescent cartilage endplate stem cells-derived exosomes induce oxidative stress injury in nucleus pulposus cells and aggravate intervertebral disc degeneration by regulating FOXO3.
Bian Z, Zhai Y, Zhang Y, Wang T, Li H, Ouyang J, Liu C, Wang S, Hu Z, Chang X, Zhang C, Liu M, Li C
Free radical biology & medicine 2025 Jun;233:39-54
Free radical biology & medicine 2025 Jun;233:39-54
Resveratrol ameliorates high‑fat diet‑induced insulin resistance via the DDIT4/mTOR pathway in skeletal muscle.
Pan X, Xue G, Zhao M, Xiang Z, Liu D, Duan Z, Wang C
Biomedical reports 2025 Jun;22(6):99
Biomedical reports 2025 Jun;22(6):99
Interaction of osteopontin with α-lactalbumin and their synergistic effects in protecting intestinal barrier injury.
He W, Wang X, Zhang J, Cao H, Ren S, Sun X, Yu H, Zhang G, Li C, Liu L, Wang C, He J
Food research international (Ottawa, Ont.) 2025 Jun;211:116513
Food research international (Ottawa, Ont.) 2025 Jun;211:116513
Echinococcus granulosus antigen B regulates T-cell function through inhibition of signal transducer and activator of transcription 3 in experimental immune thrombocytopenia.
Yue Y, Zhang Y, Cheng Y, Jiao H, Yan M
British journal of haematology 2025 Jun;206(6):1627-1641
British journal of haematology 2025 Jun;206(6):1627-1641
Extracellular pH is a critical regulator of osteoclast fusion, size and activation.
Davies BK, Skelton AJ, Hopkinson M, Lumb S, Holdsworth G, Arnett TR, Orriss IR
Bone 2025 Jun;195:117466
Bone 2025 Jun;195:117466
OTUD7B controls oxLDL uptake by stabilizing Lox-1 in THP-1 and U937 cells.
Rao Y, Li F, Wan C, Tong S, Fu Y, Li Y
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Jun;1870(5):159618
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Jun;1870(5):159618
LACC1 Enhances Polyamine Immunometabolism in Inflammatory Macrophages to Inhibit Atherosclerosis Progression.
Zhang J, Xu Y, Han Z, Liu B, Wang M, Bao L, He Y
Journal of cardiovascular translational research 2025 Jun;18(3):459-470
Journal of cardiovascular translational research 2025 Jun;18(3):459-470
Toxoplasma TgCtwh3 Δrop16 (Ⅰ/Ⅲ) accelerates neuronal apoptosis and APP production in mouse with acute infection.
Di Yang, Wang C, Tao Q, Liu L, Jin M, Cai H, Zheng M, Gong M, Yu L, Du J, Luo Q, Shen J, Qin K, Chu D
IBRO neuroscience reports 2025 Jun;18:830-843
IBRO neuroscience reports 2025 Jun;18:830-843
Full-length Chd1 of Coprinopsis cinerea is expressed after the dark period required for fruiting body maturation and impacts meiotic progression.
Abe H, Mimura S, Hatanaka K, Kakizaki T, Muraguchi H
Fungal genetics and biology : FG & B 2025 Jun;179:103988
Fungal genetics and biology : FG & B 2025 Jun;179:103988
SRSF7 promotes pulmonary fibrosis through regulating PKM alternative splicing in lung fibroblasts.
Jin T, Gao H, Wang Y, Ning Z, Bing D, Wang Y, Chen Y, Tian X, Liu Q, Niu Z, Guo J, Sun J, Yang R, Wang Q, Li S, Li T, Zhou Y, He W, Lu Y, Gu Y, Liang H
Acta pharmaceutica Sinica. B 2025 Jun;15(6):3041-3058
Acta pharmaceutica Sinica. B 2025 Jun;15(6):3041-3058
Ethyl caffeate alleviates inflammatory response and promotes recovery in septic-acute lung injury via the TNF-α/NF-κB/MMP9 Axis.
Huang Y, Li G, Li D, Liu C, Chen M, Cai L, Sun M, Xu Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156700
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156700
Glycoside components promote endothelial progenitor cell-derived exosomes repairing damaged vascular endothelium via the PI3K/AKT signaling pathway.
Tan W, Ma L, Li Y, Zhang Y, Hu Z, Li W, Ding H, Liu X, Xie L, Deng C, Zhang W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156694
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156694
Huang-Lian-Jie-Du decoction inhibits CD4+ T cell infiltration into CNS in MCAO rats by regulating BBB.
Chen C, Li C, Lan X, Ren Z, Zheng Y, Chen D, Xu W, Cui Y, Wang X, Cheng F, Wang Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156607
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156607
Influence of α-Linolenic Acid on the Intestinal Barrier Integrity and Intestinal Antioxidant Status in Broilers.
Kang A, Ni J, Cheng X, Wu S, Liu Y, Ma W, Wang D
Food science & nutrition 2025 Jun;13(6):e70271
Food science & nutrition 2025 Jun;13(6):e70271
Dimethyl Itaconate Alleviates Escherichia coli-Induced Endometritis Through the Guanosine-CXCL14 Axis via Increasing the Abundance of norank_f_Muribaculaceae.
He Y, Cai J, Xie X, Zhang X, Qu L, Liu J, Cao Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2414792
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2414792
Anti-Osteoporosis Activity of Lycopene Through ESR1: Network Pharmacology, Molecular Docking, Imaging Technology, and Experimental Validation.
Zhao B, Chen L, Wang W, Xu W, Xu B
Chemical biology & drug design 2025 Jun;105(6):e70135
Chemical biology & drug design 2025 Jun;105(6):e70135
Transient pharmacological inhibition of SUMOylation during pregnancy induces craniofacial malformations in offspring mice.
Mata-Garrido J, Zafferri I, Nordlinger A, Loe-Mie Y, Dejean A, Cossec JC
European journal of cell biology 2025 Jun;104(2):151480
European journal of cell biology 2025 Jun;104(2):151480
Rhein induces apoptosis of AGS and MGC803 cells by regulating the Ras/PI3K/AKT and p38/MAPK signaling pathway.
Wan M, Gan A, Dai J, Lin F, Wang R, Wu B, Yan T, Jia Y
The Journal of pharmacy and pharmacology 2025 Jun 9;77(6):783-793
The Journal of pharmacy and pharmacology 2025 Jun 9;77(6):783-793
SMARCB1 orchestrates cellular plasticity and oncogenic pathways in typical and chondroid chordomas.
Liu W, Regmi M, Liu S, Xiong Y, Dai Y, Wang Y, Yang J, Yang C
Scientific reports 2025 Jun 6;15(1):19942
Scientific reports 2025 Jun 6;15(1):19942
Microglia modulate integrity of myelin and proliferation of oligodendrocyte precursor cells in murine model of bone cancer pain.
Jiang L, Wang Y, Wu QZ, Yu JC, Huang YL, Xu R, Ni K, Gu XP, Ma ZL
European journal of pharmacology 2025 Jun 5;996:177585
European journal of pharmacology 2025 Jun 5;996:177585
miR-210 Regulates Autophagy Through the AMPK/mTOR Signaling Pathway, Reduces Neuronal Cell Death and Inflammatory Responses, and Enhances Functional Recovery Following Cerebral Hemorrhage in Mice.
Wang Y, Jiang L, Tian JJ, Zhu LL, Dai HJ, Guo C, Zhou LY, Wang L, Lu Y, Zhang Y
Neurochemical research 2025 Jun 5;50(3):180
Neurochemical research 2025 Jun 5;50(3):180
Metformin attenuated sepsis-related liver injury by modulating the DNA methylation and hydroxymethylation landscape.
Liu F, Tong R, Song H, Gong L, Ding X, Liu H, Li H, Liu L, Wang Y, Zhang R, Sun T
International immunopharmacology 2025 Jun 5;157:114748
International immunopharmacology 2025 Jun 5;157:114748
RBM15 promotes m6A methylation and stability of KLF6 mRNA to accelerate pyroptosis of retinal ganglion cells in early-stage diabetic retinopathy.
Zhou L, Zhang C, Cheng Q, Ma M, Fan X, Han Y, Zha X, Zhang Y
Journal of molecular histology 2025 Jun 4;56(3):183
Journal of molecular histology 2025 Jun 4;56(3):183
Effects of electroacupuncture on neural function and the expression of inflammation-related proteins NLRP3/caspase-1 in rats with ischemic stroke.
Wang Z, Xi Y, Lan J, Yang J, Shi T, Xu S, Xing L, Pan P, Wang J
Neuroreport 2025 Jun 4;36(9):456-466
Neuroreport 2025 Jun 4;36(9):456-466
In Situ Delivery of Gasdermin E mRNA Promotes Antitumor Immunity via Creatine-Elicited Type I Interferon Signaling in Monocytes.
Li H, Lu J, Tan S, Jiang T, He X, Qiao W, Hu C, Dalangood S, Lin J, Gui J
Cancer immunology research 2025 Jun 4;13(6):939-956
Cancer immunology research 2025 Jun 4;13(6):939-956
Identification of molecular subtypes and a prognostic risk model based on mitochondrial dynamic related genes in clear cell renal cell carcinoma.
Yang K, Yang K, Lei Z, Wu K, Li J, Peng Q, Liu C, Qu K, Lin T
Biochemical and biophysical research communications 2025 Jun 30;767:151911
Biochemical and biophysical research communications 2025 Jun 30;767:151911
CRM1 mediates the nuclear export of YTHDF2.
Wei S, Wang Y, Cao J, Hou J, Xie C, Gao XW
Biochemical and biophysical research communications 2025 Jun 30;767:151899
Biochemical and biophysical research communications 2025 Jun 30;767:151899
Propofol Modulates Microglial Glucose Metabolism Via the AMPK/HIF-1α Signaling Pathway To Ameliorate ECS-induced Cognitive Deficits in Depressive-like Rats.
Zou M, Min S, Hong R, Huang J, Zhou D, Liang Y
Neurochemical research 2025 Jun 30;50(4):219
Neurochemical research 2025 Jun 30;50(4):219
NR5A1 Deficiency Leads to Decidualization Dysregulation of Stromal Cells and Recurrent Spontaneous Abortion During Early Pregnancy.
Dai J, Jiang H, Liu D, Dong Z, Hu L, He F, Yu T
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 30;39(12):e70752
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 30;39(12):e70752
Mitigation of Ferroptosis in Diabetic Kidney Disease Through Mesenchymal Stem Cell Intervention via the Smad2/3/METTL3/S1PR1 Axis.
Huang LL, Hou YY, Yang J, Liao XN, Ma JS, Wang WC, Quan YX, Jiang HY, Bai YH
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 30;39(12):e70714
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 30;39(12):e70714
Deficiency of LPCAT3 Compromises Endometrial Stromal Cell Decidualization in Polycystic Ovary Syndrome.
Qi J, Zhu Z, Cao Y, Li B, Li J, Hu S, Yao G, Long Y, Zhu Q, Wang Y, He Y, Lu Y, Huang J, Ding Y, Li X, Sun Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 30;39(12):e70687
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 30;39(12):e70687
Indigenous Wild Edible Mushrooms: Unveiling the Chemical Compositions and Health Impacts.
Konsue N, Ketnawa S, Qin S
Foods (Basel, Switzerland) 2025 Jun 30;14(13)
Foods (Basel, Switzerland) 2025 Jun 30;14(13)
Sesamin improved growth and overall health in young animals by enhancing gut-liver axis function.
Chen C, Qi M, Xu Z, Wen J, Tang W, Diao H, Li Z, Chu Y, Feng F, Tang Z
Food & function 2025 Jun 3;16(11):4415-4436
Food & function 2025 Jun 3;16(11):4415-4436
Up-regulated vitronectin in Kawasaki disease shock syndrome serves as a potential biomarker.
Wei Z, Bai B, Zheng Y, Wang H, Zhang M, Zhang Q, Li X
Translational pediatrics 2025 Jun 27;14(6):1230-1244
Translational pediatrics 2025 Jun 27;14(6):1230-1244
Saroglitazar Ameliorates Pulmonary Fibrosis Progression in Mice by Suppressing NF-κB Activation and Attenuating Macrophage M1 Polarization.
Zhang Y, Lin J, Han X, Chen X
Medicina (Kaunas, Lithuania) 2025 Jun 26;61(7)
Medicina (Kaunas, Lithuania) 2025 Jun 26;61(7)
Reduced NRF2/Mfn2 activity promotes endoplasmic reticulum stress and senescence in adipose-derived mesenchymal stem cells in hypertrophic obese mice.
Fang J
World journal of stem cells 2025 Jun 26;17(6):104367
World journal of stem cells 2025 Jun 26;17(6):104367
Flos lonicerae polysaccharide alleviates inflammatory bowel disease by improving intestinal microbiota and inhibiting oxidative stress and the NF-κB pathway.
Xia Y, Zhou X, Cai P, Yan R, Ocansey DKW, Mao F
International immunopharmacology 2025 Jun 26;159:114956
International immunopharmacology 2025 Jun 26;159:114956
Narirutin attenuates LPS-induced neuroinflammatory responses in both microglial cells and wild-type mice.
Jie Z, Jing L, Jie C, Zhijie Z, Liwen D, Zhijun H, Jun Z, Linghui Z, Jianping J
International immunopharmacology 2025 Jun 26;159:114954
International immunopharmacology 2025 Jun 26;159:114954
The matrix of exosomes: Decoding the role of miRNA in macrophage polarization and oxidative stress.
Yang Y, Miao L, Hong S, Wang Q, Zhang J, Wang S
International immunopharmacology 2025 Jun 26;159:114942
International immunopharmacology 2025 Jun 26;159:114942
GDF15 suppresses abdominal aortic aneurysm by upregulating AREG expression to adjust macrophage polarization.
Wu W, Tang W, Liang W, Li Q, Qi X, Gao R, Zhou P, Chen G, Xiong J, Gu X, Ding P, Yu M, Yang C, Wen S
International immunopharmacology 2025 Jun 26;159:114899
International immunopharmacology 2025 Jun 26;159:114899
IL-33 alleviates corneal nerve damage in herpes simplex keratitis.
Liu J, Li B, Zhao B, Liu W, Yang F, Yang J, Jiang J, Hu K
International immunopharmacology 2025 Jun 26;159:114833
International immunopharmacology 2025 Jun 26;159:114833
Rebastinib attenuates acute lung injury by promoting NLRP3 ubiquitination and blocking NLRP3/GSDMD signaling pathway in macrophages and protecting alveolar epithelial cells.
Wang L, Chen H, Lu C, Ding Y, He Y, Xu J, Xu J, Zhang Z
International immunopharmacology 2025 Jun 26;159:114819
International immunopharmacology 2025 Jun 26;159:114819
NOX2/NLRP3-Inflammasome-Dependent Microglia Activation Promotes As(III)-Induced Learning and Memory Impairments in Developmental Rats.
Zhang L, Xiao Y, Wang D, Han X, Zhou R, Zhang H, Zhu K, Wu J, Sun X, Li S
Toxics 2025 Jun 26;13(7)
Toxics 2025 Jun 26;13(7)
Upregulated BAP31 Links to Poor Prognosis and Tumor Immune Microenvironment in Breast Cancer.
Hao Z, Zhao B, Zhu X, Zhang W, Wang B
International journal of molecular sciences 2025 Jun 21;26(13)
International journal of molecular sciences 2025 Jun 21;26(13)
Betulinic Acid Reduces Intestinal Inflammation and Enhances Intestinal Tight Junctions by Modulating the PPAR-γ/NF-κB Signaling Pathway in Intestinal Cells and Organoids.
Zheng X, Cao Z, Wang M, Yuan R, Han Y, Li A, Wang X
Nutrients 2025 Jun 20;17(13)
Nutrients 2025 Jun 20;17(13)
Pretreatment with Citrus reticulata 'Chachi' Polysaccharide Alleviates Alcohol-Induced Gastric Ulcer by Inhibiting NLRP3/ASC/Caspase-1 and Nrf2/HO-1 Signaling Pathways.
Liang H, Liang Y, Wu L, Lin L, Yao Y, Deng J, Xu J, Li H, Gao F, Xing W, Yu M, Jia X, Wei M, Li C, Zheng G
Nutrients 2025 Jun 20;17(13)
Nutrients 2025 Jun 20;17(13)
ESRP1 exerts anti-tumor role by promoting ferroptosis in diffuse-type gastric cancer.
Xu K, Chen H, Zhu X, Li H, Liu X, Sang Y, Wang X, Cui X, Cai B, Shang L, Chong W, Li L
Journal of experimental & clinical cancer research : CR 2025 Jun 18;44(1):176
Journal of experimental & clinical cancer research : CR 2025 Jun 18;44(1):176
Spatiotemporal Circadian Oscillator Manipulation for Enhanced Ovarian Cancer Therapy Using a Versatile Nanoplatform.
Lin J, Zhang Q, Xin Y, Lin K, Zhou Z, Yang X, Zhou Y, Wang Y, Li J, Yang H, Xie Z, Lu W, Bi Z, Guo Y, Zheng J, Shen J, Yang X, Shen J, Qi R
ACS applied materials & interfaces 2025 Jun 18;17(24):35023-35039
ACS applied materials & interfaces 2025 Jun 18;17(24):35023-35039
NR4A3 suppresses bladder cancer progression by modulating autophagy via the PI3K/AKT/mTOR pathway.
Fan L, Xu F, Liu S, Wu D, Wang S, Pan X, Zhou Y, Qu L, Zhou W
European journal of histochemistry : EJH 2025 Jun 17;69(3)
European journal of histochemistry : EJH 2025 Jun 17;69(3)
Promotion of sleep by cinnamic acid in parachlorophenylalanine-induced insomnia in rats.
Ye X, Sun C, Zhao Y, Wang W, Li Z, Liu L, Han X
International immunopharmacology 2025 Jun 17;158:114852
International immunopharmacology 2025 Jun 17;158:114852
Modulating systemic anti-inflammatory response mitigates osteoarthritis progression and associated pain after low-dose radiotherapy.
Ma G, Yang Y, Li S, Li L, Meng X, Rong Y, Tang M, Cheng Q, Guo H, Li Q, Jin X
International immunopharmacology 2025 Jun 17;158:114815
International immunopharmacology 2025 Jun 17;158:114815
Halicin Reduces the Warburg Effect and Overcomes Drug Resistance by Activating the Pyruvate Kinase M2 Pathway for Triple-Negative Breast Cancer Treatment.
Gu H, You W, Zhou XH, Wang Z, Huo SH, Nie X, Feng YB, You YZ, Zhan X, Xia L
ACS omega 2025 Jun 17;10(23):24541-24554
ACS omega 2025 Jun 17;10(23):24541-24554
Hypothalamic kisspeptin alleviates myasthenia gravis by regulating Th1/Th17/Treg balance through Inhibition of NF-κB signaling pathway.
Lu D, Liu L, Que W, Fan R, Ke P, Dong J, Gan Y, Xiao F
Journal of neuroinflammation 2025 Jun 16;22(1):158
Journal of neuroinflammation 2025 Jun 16;22(1):158
Alternative splicing of uromodulin enhances mitochondrial metabolism for adaptation to stress in kidney epithelial cells.
Nanamatsu A, Rhodes GJ, LaFavers KA, Micanovic R, Lazar V, Khan S, Barwinska D, Makino S, Zollman A, Cheng YH, Doud EH, Mosley AL, Repass MJ, Kamocka MM, Baride A, Phillips CL, Kelly KJ, Eadon MT, Himmelfarb J, Kretzler M, Bacallao RL, Dagher PC, Hato T, El-Achkar TM
The Journal of clinical investigation 2025 Jun 16;135(12)
The Journal of clinical investigation 2025 Jun 16;135(12)
Tiliroside induces ferroptosis and suppresses tumor growth by synergistically targeting AKR1B1 and modulating iron metabolism in ovarian cancer cells.
Chen L, Ma N, Liu D, Li Y, Ci X, Wei Z
European journal of pharmacology 2025 Jun 15;997:177591
European journal of pharmacology 2025 Jun 15;997:177591
Human Amniotic Fluid-Derived Exosomes Alleviate Neuropathic Pain by Inducing an Anti-Inflammatory Transition in Microglia.
Li Q, Dai H, Zhang S, Li P, Peng L, Chen Y, Guo Q, Yang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 15;39(11):e70664
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 15;39(11):e70664
Luteolin Potentially Alleviates Methamphetamine Withdrawal-Induced Negative Emotions and Cognitive Deficits Through the AKT/FOXO1/HO-1 Signaling Pathway in the Prefrontal Cortex and Caudate Putamen.
Gao B, An R, Liang M, Wang X, Peng J, Chen X, Liu Z, Li T, Liu X, Zhang J, Han W
International journal of molecular sciences 2025 Jun 15;26(12)
International journal of molecular sciences 2025 Jun 15;26(12)
Excitation-inhibition imbalance in the auditory cortex causes sound recognition impairment in noisy environment in hidden hearing loss mice.
Zhang M, Zhu J, Jiang Y, Chang T, Fu Y, Wu K, Zheng Z, Zhang Z, Wang X
Brain research bulletin 2025 Jun 15;226:111371
Brain research bulletin 2025 Jun 15;226:111371
Adipose-derived stem cells extracellular vesicles enhance diabetic wound healing via CCN2/PI3K/AKT pathway: therapeutic potential and mechanistic insights.
Zhou YL, Ogura S, Ma H, Liang RB, Fang SY, Wang YM, Wo Y, Wang WJ, Liu DW
Stem cell research & therapy 2025 Jun 15;16(1):304
Stem cell research & therapy 2025 Jun 15;16(1):304
Overexpression of the circadian gene Bmal1 regulates the Nrf2/HO-1 oxidative stress pathway to alleviate inflammation and apoptosis in PC12 cells following cerebral ischemia-reperfusion injury.
Zeng F, Wang M, Li Z, Zhang Y
Medicine 2025 Jun 13;104(24):e42763
Medicine 2025 Jun 13;104(24):e42763
Lysine-Targeted Covalent Strategy Leading to the Discovery of Novel Potent PROTAC-Based PI3Kδ Degraders.
Yuan B, Liu J, Wu Y, Chen M, Lai Y, Zhao HY, Yang Z, Zhang SQ, Xin M
Journal of medicinal chemistry 2025 Jun 12;68(11):11437-11467
Journal of medicinal chemistry 2025 Jun 12;68(11):11437-11467
Discovery of Highly Potent, Selective, and Liver-Targeting HSD17B13 Inhibitor with Robust In Vivo Anti-MASH Activity.
Chen L, Liang Z, Mao J, Liao Z, Liu Y, Ou D, Liu C, Li Z
Journal of medicinal chemistry 2025 Jun 12;68(11):11127-11148
Journal of medicinal chemistry 2025 Jun 12;68(11):11127-11148
Psoraleae Fructus affects the livers of normal and ulcerative colitis rats differently by altering bile acid metabolism.
Liu X, Zhao Y, Liu C, Li C, Yi Y, Liu S, Tang X, Pan C, Zhang Y, Tian J, Han J, Yue X, Liang A
Journal of ethnopharmacology 2025 Jun 12;349:119849
Journal of ethnopharmacology 2025 Jun 12;349:119849
FOXO1 contributes to cigarette smoke condensate-induced cellular senescence and fibrosis in lung fibroblasts through activating the TGF-β1/Smad2/3 signaling pathway.
Zheng M, Yuan G, Han J, Li J, Jiang Y, Li Z, Yao Y
Immunologic research 2025 Jun 11;73(1):94
Immunologic research 2025 Jun 11;73(1):94
A Dual-Factor Scaffold for Spinal Cord Injury Repair Targeting Inflammation and Ferroptosis.
Zou X, Zhu Y, Shu H, Su X, Xiong J, Ye W, Tang P, Wang H, Gao Y, Song T, Zou Z, Cai W
ACS applied materials & interfaces 2025 Jun 11;17(23):33540-33554
ACS applied materials & interfaces 2025 Jun 11;17(23):33540-33554
Potential targets for synergistic bipolar irreversible electroporation in tumor suppression through transcriptomics and proteomics analysis.
Wang Y, Liu X, Liu R, Qian K, Zhu T, Liu H, Zhou Q, Dong S, Liu H, Yao C
Gene 2025 Jun 10;952:149420
Gene 2025 Jun 10;952:149420
Durable HTT silencing using non-evolved dCas9 epigenome editors in patient-derived cells.
Waldo JJ, Halmai JANM, Singh A, Gonzalez CE, Chen YA, Carthen SA, Nolta JA, Fink KD
Molecular therapy. Nucleic acids 2025 Jun 10;36(2):102561
Molecular therapy. Nucleic acids 2025 Jun 10;36(2):102561
The gut microbiota-mediated ferroptosis pathway: a key mechanism of ginsenoside Rd against metabolism-associated fatty liver disease.
Liu W, Zhou X, Xiao L, Huang X, Chang D, Zhong X, Zeng M, Xian Y, Zheng Y, Huang W, Huang R, Huang M
Chinese medicine 2025 Jun 10;20(1):83
Chinese medicine 2025 Jun 10;20(1):83
Mesenchymal Stem Cell-Derived Mitochondrial Transfer Promotes Tip Cell Phenotype via Glutathione Metabolic Reprogramming in Stroke Mice.
Zhang Q, Huang J, Chen X, Li L, Chen L, Zhou X, Zhao X, Liu M, Zhao W, Yan J, Wang Y, Su Y, Liu Y, Xu S, Zeng W
ACS nano 2025 Jun 10;19(22):20452-20471
ACS nano 2025 Jun 10;19(22):20452-20471
Discovery and characterization of novel FAK inhibitors for breast cancer therapy via hybrid virtual screening, biological evaluation and molecular dynamics simulations.
Chi X, Chen R, Chen R, Xu Y, Deng Y, Yang X, Pan Z, Xu X, Pan Y, Li Q, Zhou P, Huang W
Bioorganic chemistry 2025 Jun 1;159:108400
Bioorganic chemistry 2025 Jun 1;159:108400
A novel MMP-9 inhibitor exhibits selective inhibition in non-small-cell lung cancer harboring EGFR T790M mutation by blocking EGFR/STAT3 signaling pathway.
Li L, Lu M, Wang H, Ma X, Du W, Zhao Y, Zeng S, Peng Y, Zhang G
Bioorganic chemistry 2025 Jun 1;159:108393
Bioorganic chemistry 2025 Jun 1;159:108393
Tarm1 may affect colitis by regulating macrophage M1 polarization in a mouse colitis model.
Zhang K, Xu L, Guo J
Pediatric research 2025 Jul;98(1):286-293
Pediatric research 2025 Jul;98(1):286-293
UGDH promotes 5-fluorouracil resistance in colorectal cancer via the ROS-activated PI3K/AKT-EEF1A2-PRDX1 pathway.
Cai J, Zhou R, Ye Y, Hao J, Luo Q, Mei H, He Z, Wang F, Yalikun A, Yu Y, Wen Y
Archives of biochemistry and biophysics 2025 Jul;769:110445
Archives of biochemistry and biophysics 2025 Jul;769:110445
Pharmacological inhibition of Septins with Forchlorfenuron attenuates thrombus formation in experimental thrombotic mice models with modulating multiple signaling pathways in platelets.
Hao Z, Yan M, Tuerhong R, Zhang L, Zhang Z, Alam H, Wu J, Qin Y, Zhao F, Shi L
Journal of advanced research 2025 Jul;73:517-533
Journal of advanced research 2025 Jul;73:517-533
Potential of Ginger Oil to Prevent 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone-Induced Lung Cancer Through Gut Microbiota Modulation and Inflammatory Response Inhibition.
Ding Y, Zhang L, Zhao W, Wang T, Shi Y, Zhuang C, Qu Z
Molecular nutrition & food research 2025 Jul;69(13):e70103
Molecular nutrition & food research 2025 Jul;69(13):e70103
PELI1 silencing delays intervertebral disc degeneration by impeding nucleus pulposus cell death.
Wei X, Yu C, Wang J
Connective tissue research 2025 Jul;66(4):298-310
Connective tissue research 2025 Jul;66(4):298-310
SERP1 Alleviates Cerebral Ischemia/Reperfusion Injury by Inhibiting ER Stress-Mediated Apoptosis.
Yin L, Wang D, Zhang X, Wang X, Jiao H, Liu X, Zheng J
Cell biology international 2025 Jul;49(7):878-894
Cell biology international 2025 Jul;49(7):878-894
Deubiquitinase TRIM44 Promotes Autophagy-Mediated Chemoresistance in Diffuse Large B Cell Lymphoma.
Wang Y, Li B, Zhao Y, Zhu X, Wang B, Yang L, Feng R, Teng Q
Hematological oncology 2025 Jul;43(4):e70119
Hematological oncology 2025 Jul;43(4):e70119
Advanced N-glycoproteomics and proteomics approach revealed sexually dimorphic molecular signatures in primary mouse hepatocyte.
Yang Q, Zhang Y, Zhang H, Yang Z, Feng Y, Ye B, Gong P, Qian G, Li D
Analytical and bioanalytical chemistry 2025 Jul;417(17):3893-3908
Analytical and bioanalytical chemistry 2025 Jul;417(17):3893-3908
Modulation of SUMO1-TOP1 DNA damage repair by TOPORS following ovalbumin-induced oxidative stress in macrophages.
Cai X, Xu Q, Yin T, Li X, Cheng Y, Li X, Hao C
Toxicology letters 2025 Jul;410:130-138
Toxicology letters 2025 Jul;410:130-138
Inhibition of circ_0127646 Enhanced the Cisplatin Sensitivity in Osteosarcoma Cells via miR-22/KAT6B Axis.
Chang M, Chen Q, Sun C, Shi X, Wu S, Zheng L, Zhou X
Journal of biochemical and molecular toxicology 2025 Jul;39(7):e70381
Journal of biochemical and molecular toxicology 2025 Jul;39(7):e70381
Small extracellular vesicles from adipose derived stem cells alleviate microglia activation and improve motor deficit of Parkinson's disease via miR-100-5p/DTX3L/STAT1 signaling axis.
Feng N, Huang X, Jia Y
Experimental neurology 2025 Jul;389:115250
Experimental neurology 2025 Jul;389:115250
Methacrylated sericin/methacrylated hyaluronic acid composite microneedles with exosomes for diabetic wound healing.
Xu X, Shen Y, Wu J, Hong F, Xia H, Chen X, Lin G, Liu L, Xu RA
International journal of biological macromolecules 2025 Jul;318(Pt 1):144957
International journal of biological macromolecules 2025 Jul;318(Pt 1):144957
Targeting PD-L1 for Ischemic Stroke Recovery: Age-Dependent Modulation of Immune and BBB Pathways.
Hang H, Xu C, Wang L, Liu C, Zhang R, Wu G, Zhao H
CNS neuroscience & therapeutics 2025 Jul;31(7):e70523
CNS neuroscience & therapeutics 2025 Jul;31(7):e70523
Xuefu Zhuyu Decoction Improves Blood-Brain Barrier Integrity in Acute Traumatic Brain Injury Rats via Regulating Adenosine.
Wang Y, Yan QJ, Hu E, Wu Y, Ding RQ, Chen Q, Cheng MH, Yang XY, Tang T, Li T
Chinese journal of integrative medicine 2025 Jul;31(7):624-634
Chinese journal of integrative medicine 2025 Jul;31(7):624-634
Porcine reproductive and respiratory syndrome virus nsp2-related proteins induce host translational arrest by specifically impairing the mTOR signaling cascade.
Jiao X, Chen X, Li Q, Li C, Li Y
Veterinary microbiology 2025 Jul;306:110562
Veterinary microbiology 2025 Jul;306:110562
Transthyretin, a novel prognostic marker of POCD revealed by time-series RNA-sequencing analysis.
Liang X, Song C, Lin J, Li S, Li L, Dai G, Zhang R, Zou OM, Yao H, Zhou L, Zou Y
Molecular psychiatry 2025 Jul;30(7):3103-3119
Molecular psychiatry 2025 Jul;30(7):3103-3119
Melatonin ameliorates heat stress-induced oxidative apoptosis in mouse spermatocytes via autophagy and ferroptosis pathways.
Lei YP, Wang J, Yin PL, Jia H, Ma WZ
Cell stress & chaperones 2025 Jul;30(4):100078
Cell stress & chaperones 2025 Jul;30(4):100078
Protein succinylome analysis identifies citrate synthase as a central regulator of osteoclast metabolic activity.
Yu D, Gao Y, Luzarowski M, Seebach E, Heitkamp T, Börsch M, Ruppert T, Kubatzky KF
The FEBS journal 2025 Jul;292(14):3736-3754
The FEBS journal 2025 Jul;292(14):3736-3754
A novel IgD-FcδR blocker, IgD-Fc-Ig fusion protein, effectively alleviates abnormal activation of T cells the disease progression in systemic lupus erythematosus.
He J, Liu D, Jiang L, Chen M, Ling X, Dong M, Wu T, Guo T, Xu N, Zhang J, Li T, Wang Y, Zhao J, Wei W, Yan S, Wu Y
Biochemical pharmacology 2025 Jul;237:116930
Biochemical pharmacology 2025 Jul;237:116930
Vascular cellular senescence in human atherosclerosis: The critical modulating roles of CDKN2A and CDK4/6 signaling pathways.
Hu G, Zhou H, Yuan Z, Wang J
Biochemical pharmacology 2025 Jul;237:116916
Biochemical pharmacology 2025 Jul;237:116916
Nicotinamide mononucleotide mitigates hyperoxia-aggravated septic lung injury via the GPx4-mediated anti-ferroptosis signaling pathway in alveolar epithelial cells.
Zhao N, Tao W, Ouyang X, Yang X, Sun Z, Liu F, Qian K
Free radical biology & medicine 2025 Jul;234:86-99
Free radical biology & medicine 2025 Jul;234:86-99
Identification of cytochrome P450 2E1 as a novel target in neuroinflammation and development of its inhibitor Q11 as a treatment strategy.
Yang R, Deng MY, Yang LK, Wang GZ, Ma J, Wen Q, Gao N, Qiao HL
Free radical biology & medicine 2025 Jul;234:220-232
Free radical biology & medicine 2025 Jul;234:220-232
Liyan Kaiyin Formula relieves reflux pharyngitis by regulating M1 macrophage polarization via the NF-κB/NLRP3 pathway.
Wang L, Chen X, Xu T, Fei Y, Yang Q, An J, Li Z, Wu K
Immunobiology 2025 Jul;230(4):153095
Immunobiology 2025 Jul;230(4):153095
Phellodendrine chloride alleviates gouty arthritis through IL-6/STAT3 signaling pathway.
Qin YY, Qin ZY, Liang T, Qin DE, Hua SY, Tan MH, Guo S, Yang F, Shi L, Yu Y, Zhang GJ
Immunobiology 2025 Jul;230(4):152918
Immunobiology 2025 Jul;230(4):152918
Therapeutic time window of sodium of Danshensu on cerebral ischemia and its mechanism of inhibiting oxidative stress and ferroptosis through Nrf2 pathway.
Guo C, Ma Z, Tao X, Gao K, Zhang W, Wen A, Ding Y, Wang J
Brain research bulletin 2025 Jul;227:111396
Brain research bulletin 2025 Jul;227:111396
Curcumin modulates the PTEN/PI3K/AKT pathway to alleviate inflammation and oxidative stress in PM2.5-Induced chronic obstructive pulmonary disease.
Liu K, Shi M, Li X, Zeng X, Liu X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Jul;201:115460
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Jul;201:115460
cba-miR-222-3p involved in photoperiod-induced apoptosis in testes of striped hamsters by targeting TRAF7.
Wang S, Xu J, Wang X, Wang M, Xue H, Wu M, Fan C, Chen L, Xu L
Integrative zoology 2025 Jul;20(4):836-849
Integrative zoology 2025 Jul;20(4):836-849
Thermo-responsive nano-hydrogel-based delivery of Saikosaponin a to enhance anti-PD-1 therapy in osteosarcoma.
Chen YQ, Yang D, Li K, Liu JS, Feng HJ, Zhou JW
Nanomedicine (London, England) 2025 Jul;20(14):1677-1691
Nanomedicine (London, England) 2025 Jul;20(14):1677-1691
Integrating LC-MS and molecular docking technology to investigate the effect of Spatholobi caulis flavonoids in alleviating primary dysmenorrhea via regulating the RhoA/ROCK pathway.
Zhang X, Weng J, Luo Y, Liu H, Yan J, Gong Z, Kong C, Li X, Yang L, Jiang M
Fitoterapia 2025 Jul;184:106631
Fitoterapia 2025 Jul;184:106631
Anti-inflammatory mechanism of Achyranthes longifolia extract and its component chikusetsusaponin IVa by modulating Nrf2/NF-κB pathways in vitro and in vivo.
Zeng Q, Xiao W, Zhang H, Liu W, Wang X, Li Z, Han Y, Wang Z, Yan Q, Ai Q, Yang J, Li S, Ouyang W
Fitoterapia 2025 Jul;184:106593
Fitoterapia 2025 Jul;184:106593
Guaiane sesquiterpenoid-Glucozaluzanin C from Ainsliaea fragrans Champ. targets TLR4/p65 to regulate NF-κB/MAPK pathway, alleviating sepsis-induced acute liver injury.
Lai M, Cui Y, Yang Y, Wang Z, Yao M, Yang S, Li J, Feng Y
Fitoterapia 2025 Jul;184:106579
Fitoterapia 2025 Jul;184:106579
NRF2 modulates WNT signaling pathway to enhance photodynamic therapy resistance in oral leukoplakia.
Xu T, Zhong L, Liu Q, Wang F, Kuang W, Liang J, Yang D, Zhou X, Dan H, Zhao H, Li T, Zeng X, Li J, Chen Q
EMBO molecular medicine 2025 Jul;17(7):1794-1824
EMBO molecular medicine 2025 Jul;17(7):1794-1824
Role of UBC9 in the inflammatory response and pathogen susceptibility in zebrafish.
Shah PT, Guo F, Feng J, Wu C, Xing L
Fish & shellfish immunology 2025 Jul;162:110337
Fish & shellfish immunology 2025 Jul;162:110337
Proteomics suggests the role of Cxcl12 secreted by hucMSCs in the treatment of lipopolysaccharide-acute lung injury.
Cui J, Luo L, Geng H, Gao Y, Chen Y, Yu Q, Huang X, Wang X, Sun T
Microvascular research 2025 Jul;160:104815
Microvascular research 2025 Jul;160:104815
Design, synthesis, and antitumor activity of novel thioheterocyclic nucleoside derivatives by suppressing the c-MYC pathway.
Li XJ, Huang KX, Wang KX, Liu R, Wang DC, Liang YR, Hao EJ, Wang Y, Guo HM
Acta pharmaceutica Sinica. B 2025 Jul;15(7):3685-3707
Acta pharmaceutica Sinica. B 2025 Jul;15(7):3685-3707
Diosmetin attenuates the ubiquitination of epidermal hypoxia-inducible factor 1 alpha by diminishing the formation of RhoBTB3/PHD2 complex in ultraviolet radiation-induced sunburn in mice.
Gong X, Yang S, Yuan Z, Zhang Z, Ali F, Zhang F, Zhang B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156793
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156793
Refined qingkailing attenuates reactive astrocytes and glial scar formation after ischemia stroke via the EGFR/PLCγ pathway.
Ren ZL, Zhang CX, Zheng YX, Chen CA, Dan-Chen, Lan X, Yan X, Liu Y, He YH, Cheng JL, Han JH, Wang QG, Wang XQ, Cheng FF, Li CX
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156696
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156696
Peiyuan Ningshen-ointment alleviates learning and memory impairment induced by sleep deprivation through activating the cAMP/PKA signaling pathway.
Wei XY, Xu FP, Chen XB, Xu Q, Deng LY, Sun C, Chen XY, Tan F, Yang ZM
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156469
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156469
Catharanthine tartrate ameliorates osteoclastogenesis by destabilizing HIF-1α.
Cai L, Yu C, Zhao B, Wu Q, Liang H, Zhou M, Miao J, Luo J, Xu J, Jin H, Pan Y
Cellular signalling 2025 Jul;131:111779
Cellular signalling 2025 Jul;131:111779
Analysis of the Aerial Parts of Millettia speciosa Champ. and Mechanistic Study of Its Active Ingredient Formononetin in Improving Metabolic Syndrome.
Niu W, Jian R, Zeng L, Huang Z, Cai J
Food science & nutrition 2025 Jul;13(7):e70601
Food science & nutrition 2025 Jul;13(7):e70601
Mechanism of antithrombin deficiency due to the novel variant C32W in the C-terminus of the signal peptide.
Kikuchi Y, Nagaya S, Togashi T, Imai Y, Togashi M, Araiso Y, Nishiuchi T, Morishita E
International journal of hematology 2025 Jul;122(1):35-44
International journal of hematology 2025 Jul;122(1):35-44
CNS Mitochondria-Derived Vesicle in Blood: Potential Biomarkers for Brain Mitochondria Dysfunction.
Liu Q, Chen W, Wu Y, Guo Z, Chen J, Tian C, Wang P, Zeng S, Xu B, Duan J, Han S, Xiong X, Zhang J
Annals of clinical and translational neurology 2025 Jul;12(7):1312-1323
Annals of clinical and translational neurology 2025 Jul;12(7):1312-1323
Genetic Regulation of Alternative Polyadenylation Provides Novel Insights into Molecular Mechanisms Underlying Non-small Cell Lung Cancer.
Jin M, Huang Y, Li B, Wang Y, Li Y, Chen Z, Tang Z, Liu C, Zhang L, Yuan X, Tian J, Liu B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(26):e2502008
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(26):e2502008
Lactate production by tumor-resident Staphylococcus promotes metastatic colonization in lung adenocarcinoma.
Yu H, Du Y, He Y, Sun Y, Li J, Jia B, Chen J, Peng X, An T, Li J, Chi Y, Wang M, Cao L, Tai Y, Zhai X, Nuersulitan R, Li S, Wu N, Wang J, Xiong H, Wan S, Liu J, Yang X, Hu X, Lin D, Sun W, Wang Y, An G, Ji X, Kong L, Ding L, Ma Y, Tian Z, Dong B, Bi Y, Wu J, Wang Z
Cell host & microbe 2025 Jul 9;33(7):1089-1105.e7
Cell host & microbe 2025 Jul 9;33(7):1089-1105.e7
ELAVL1-mediated USP29 mRNA degradation activates TAK1 driving M1 microglial polarization and neural stem cell differentiation dysregulation in spinal cord injury.
Sha C, Pan F, Liu X, Wang Z, Liu G, Huang K
Cell death discovery 2025 Jul 9;11(1):317
Cell death discovery 2025 Jul 9;11(1):317
Acevaltrate as a novel ferroptosis inducer with dual targets of PCBP1/2 and GPX4 in colorectal cancer.
Yu D, Hu H, Zhang Q, Wang C, Xu M, Xu H, Geng X, Cai M, Zhang H, Guo M, Lu D, Xu H, Li L, Zhang X, Shen R, Lin S, Wang Q, Zhang W, Liu S
Signal transduction and targeted therapy 2025 Jul 7;10(1):211
Signal transduction and targeted therapy 2025 Jul 7;10(1):211
Hydroxychloroquine improves manifestation of PE rats under oxidative stress by regulating the PI3K/AKT/mTOR signaling pathway to inhibit autophagy.
Han W, Jing X, XiaoYan C, Wen HW, Xia F, Qin RQ, Ying W, Xia L, Man W, Xiu W
Scientific reports 2025 Jul 6;15(1):24099
Scientific reports 2025 Jul 6;15(1):24099
FGF13 prevents age-related hearing loss by protecting spiral ganglion neurons and ribbon synapses from injury.
Yin H, Cao H, Yang J, Liu T, Li Q, Liu M, Wang B
Cell death discovery 2025 Jul 5;11(1):307
Cell death discovery 2025 Jul 5;11(1):307
Adipocytes-induced ANGPTL4/KLF4 axis drives glycolysis and metastasis in triple-negative breast cancer.
Yin D, Fang N, Zhu Y, Bao X, Yang J, Zhang Q, Wang R, Huang J, Wu Q, Ma F, Wei X
Journal of experimental & clinical cancer research : CR 2025 Jul 4;44(1):192
Journal of experimental & clinical cancer research : CR 2025 Jul 4;44(1):192
Cholesterol confers resistance to Apatinib-mediated ferroptosis in gastric cancer.
Li Z, Liu C, Wang M, Wei R, Li R, Huang K, Liang H, Li G, Zhao L
Cell & bioscience 2025 Jul 4;15(1):95
Cell & bioscience 2025 Jul 4;15(1):95
Aerobic exercise alleviates cognitive impairment in T2DM mice through gut microbiota.
Ruan S, Liu J, Yuan X, Ye X, Zhang Q
Scientific reports 2025 Jul 4;15(1):23917
Scientific reports 2025 Jul 4;15(1):23917
Nanosilicates promote angiogenesis through activation of ROS-mediated WNT/β-catenin pathway.
Lokhande G, Singh KA, Roy S, Soukar J, Kersey A, Borkar P, Biswas S, Syed RUR, Keller A, Bayless KJ, Singh I, Gaharwar AK
Science advances 2025 Jul 4;11(27):eado1223
Science advances 2025 Jul 4;11(27):eado1223
An Integrated Analysis of Transcriptomics and Metabolomics Elucidates the Role and Mechanism of TRPV4 in Blunt Cardiac Injury.
Gao L, Han L, Ma X, Wang H, Li M, Cai J
Metabolites 2025 Jul 31;15(8)
Metabolites 2025 Jul 31;15(8)
Exercise-induced lactate suppresses ccRCC via CNDP2-mediated depletion of intracellular amino acids.
Miao R, Liu C, Wang Y, Li H, Han C, Wang C, Tian Z, Liu J
Cell death discovery 2025 Jul 31;11(1):356
Cell death discovery 2025 Jul 31;11(1):356
GPR146 regulates CYP7A1 transcription in cells and in vivo of mice.
Liu X, Han J, Li X, Zhang Z, Li J, Yao Y
Biochemical and biophysical research communications 2025 Jul 30;772:152045
Biochemical and biophysical research communications 2025 Jul 30;772:152045
miR-708-5p Attenuates Osteoarthritis Progression via Multi-Target Modulation of the NOX4/NF-κB Axis and Cartilage Homeostasis.
Huang SH, Liu ZM, Chen SJ, Tu PY, Tien YC, Lu CC, Wang CC, Chen LM, Shen PC
Cartilage 2025 Jul 30;:19476035251361679
Cartilage 2025 Jul 30;:19476035251361679
Mefunidone treats pulmonary fibrosis by targeting SDH to regulate fibro-promoting macrophages.
Zhang X, He Y, Long L, Jiang G, Yao T, Cheng X, Peng Z, Hu G, Tao L, Meng J
International immunopharmacology 2025 Jul 28;160:114971
International immunopharmacology 2025 Jul 28;160:114971
Dual Role of Quercetin in Promoting Early Wound Healing via Inhibiting Inflammatory Factors and Attenuating Scar Formation by Suppressing Myofibroblast Differentiation.
Wu D, Jiang M, Zhang J
Frontiers in bioscience (Landmark edition) 2025 Jul 25;30(7):40077
Frontiers in bioscience (Landmark edition) 2025 Jul 25;30(7):40077
Dysfunction of Autophagy in Adipose Tissue Macrophages Regulated via FoxO1 in Obesity-Related Severe Acute Pancreatitis.
Ling X, Zhang Z, Lin L, Guo X, Ding Z
International journal of molecular sciences 2025 Jul 25;26(15)
International journal of molecular sciences 2025 Jul 25;26(15)
The promoting effect of high-fat diet-induced trained immunity on ulcerative colitis and the mechanism of the therapeutic effect of Dahuang Mudan Decoction.
Li P, Xu R, Chen H, Cao S, Xie X, Xu B, Chen Y, Xie X, Yang C, Wang Q, Luo X, Zhou L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156893
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156893
Dahuang Huanglian Decoction alleviates dysbiosis by inhibiting GBP5/NLRP3 signaling pathway-mediated pyroptosis of colonic epithelial cells.
Ren T, Yin Y, Zhou X, Chen L, Shen Y, Feng H, Zhou C, Xu Y, Ling Y
Journal of ethnopharmacology 2025 Jul 24;351:120143
Journal of ethnopharmacology 2025 Jul 24;351:120143
Exploring the mechanism of feiyanning formula and its extract apigenin against EGFR-TKIs resistance in non-small cell lung cancer based on UPLC-HRMS and experimental validation.
Han Y, Jiao L, Zhou H, Sang S, A G, Liu R, Du Y, Wang M, Kang X, Wang Q, Gong Y
Journal of ethnopharmacology 2025 Jul 24;351:120120
Journal of ethnopharmacology 2025 Jul 24;351:120120
Cornus officinalis loganin attenuates acute lung injury in mice via regulating the PI3K/AKT/NLRP3 axis.
Liu Y, Wang C, Hui T, Yuan Y, Chen S, Li Y, Wang G, Kang J, Xue X
Journal of ethnopharmacology 2025 Jul 24;351:120104
Journal of ethnopharmacology 2025 Jul 24;351:120104
Lichong Decoction represses colorectal cancer progression via inhibiting the PINK1/Parkin pathway regulated by Rab27B.
Dai Y, Li F, Tang Y, Sun L, Liu Y, Zhan J, Zhou C, Li A
Journal of ethnopharmacology 2025 Jul 24;351:119997
Journal of ethnopharmacology 2025 Jul 24;351:119997
KRAS amplification in colorectal cancer: correlations with clinicopathological features and prognosis in patients and prediction of response to targeted therapy.
Yang X, Feng S, Zhang Q, Li W, Li S, Zhi M, Lan P, Cheng S
Journal of translational medicine 2025 Jul 24;23(1):824
Journal of translational medicine 2025 Jul 24;23(1):824
1,6-Digalloyl glucose in Emblica officinalis increases the proliferation of human keratinocytes and fibroblasts with upregulated expression of periostin.
Yamakami Y, Morino K, Kanaly RA, Irie R, Oikawa M, Takauji Y, Miki K, Hossain MN, Ayusawa D, Fujii M
Bioscience, biotechnology, and biochemistry 2025 Jul 23;89(8):1092-1105
Bioscience, biotechnology, and biochemistry 2025 Jul 23;89(8):1092-1105
DSS1 inhibits autophagy to activate epithelial-mesenchymal transition in a pro-metastatic niche of renal cell carcinoma.
Chen X, Liu Q, Wu J, Zhou P, Zhao M, Song J
Nature communications 2025 Jul 23;16(1):6769
Nature communications 2025 Jul 23;16(1):6769
METTL3 regulates PRRSV replication by suppressing interferon beta through autophagy-mediated IKKε degradation.
Zhai Y, Wang L, Lv L, Zhao X, Li M, Tian J, Qiu X, Yao L, Zhu W, Kang Y, Zhang A, Zhuang G, Sun A
Journal of virology 2025 Jul 22;99(7):e0009825
Journal of virology 2025 Jul 22;99(7):e0009825
TGF-β/snail-mediated epithelial-to-mesenchymal transition disrupts estradiol metabolism through suppressing the HSD17B2 expression in endometriotic epithelial cells.
Jin P, Cai J, Chen N, Liu Y, Zhao H, Wang Y, Chen J, Li M, Xiao T, Shan C, Yu M, Zhang JV
Biochemical and biophysical research communications 2025 Jul 22;771:151964
Biochemical and biophysical research communications 2025 Jul 22;771:151964
Investigation of the molecular mechanism of Xiaoluo Wan in thyroid-associated ophthalmopathy: network analysis and in vivo study.
Gu W, Tian S, Fu L, Wang L, Zhang L, Wang F
Hereditas 2025 Jul 22;162(1):137
Hereditas 2025 Jul 22;162(1):137
The MFGE8/integrin β3 axis mitigates experimental neutrophilic asthma by suppressing NLRP3-Caspase-1 pathway-mediated NETosis.
Wang S, Kun T, Tian Z, Huang M, Fan Y, Li B, Zheng H, Xu R, Wang M, Zhao J, Xie J
Respiratory research 2025 Jul 2;26(1):229
Respiratory research 2025 Jul 2;26(1):229
High-Fat Diet-Induced Diabetic Cardiomyopathy in Female Zebrafish: Cardiac Pathology and Functional Decline Mediated by Type 2 Diabetes.
Huang S, Chen Z, Li H, Zou Y, Wang B, Zhao W, Zheng L, Zhou Z, Peng X, Tang C
Nutrients 2025 Jul 2;17(13)
Nutrients 2025 Jul 2;17(13)
Non-invasive assessment of stem cell DNA integrity in response to environmental stressors.
Wang J, Zhou Y, Zhuo L, Yan B, Ma L
Scientific reports 2025 Jul 2;15(1):22960
Scientific reports 2025 Jul 2;15(1):22960
Macrophage migration inhibitory factor mediates joint capsule fibrosis via facilitating phospholipid metabolite PGE2 production in fibroblasts.
Zhang Y, Jiao X, Wang Y, Liu S, Wang Z, Chang H, Li Y, Yue X, Gu X, Xu R
Cellular and molecular life sciences : CMLS 2025 Jul 19;82(1):279
Cellular and molecular life sciences : CMLS 2025 Jul 19;82(1):279
Reactive oxygen species regulate adipose-osteogenic lineage commitment of human mesenchymal stem cells by modulating gene expression of C/EBP homology protein and aldo-keto reductase family 1 member A1.
Chiang CH, Kao YC, Lin YH, Ma YS, Wu YT, Jian BY, Wei YH, Chen CM, Liou YM
Cell & bioscience 2025 Jul 18;15(1):104
Cell & bioscience 2025 Jul 18;15(1):104
Secreted phosphoprotein 1 promotes the activation of keloid fibroblasts via the CD44/TGF-β1/Smad pathway.
Tu Y, Xiong Y, Liu O, Peng Y
Experimental cell research 2025 Jul 15;450(2):114658
Experimental cell research 2025 Jul 15;450(2):114658
MS275 Inhibits Neuroblastoma Cell Growth by Mediating H3K27ac/PROX1 Axis In Silico and In Vitro.
Yuan C, Li C, Lu J, Liao S, Wu R, Li D, Huang M, Gong D, Wu W, Yu X, Fei S, Si W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 15;39(13):e70797
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 15;39(13):e70797
Peptide Cy(RL-QN15) alleviates UVB-induced skin aging by promoting the repair of barrier.
Kang Z, Yin S, Han X, Liu X, Peng Y, Jia Q, Fu Z, Li Y, Wu Y, Xiao Z, Li Z, Wang Y, Luo M, Yang X
Ecotoxicology and environmental safety 2025 Jul 15;300:118465
Ecotoxicology and environmental safety 2025 Jul 15;300:118465
S-COS-Se mitigates cadmium-induced oxidative stress, inflammation, and immunotoxicity by restoring immune balance and inhibiting mitochondria-pyroptosis crosstalk.
Zheng H, Dong W, Qiu H, Gao S, Hou L, Dong J, Zhao P, Chen F
Ecotoxicology and environmental safety 2025 Jul 15;300:118462
Ecotoxicology and environmental safety 2025 Jul 15;300:118462
Exosomes derived from ALR-modified adipose mesenchymal stem cells mediate hepatoprotective effects on hepatic ischemia-reperfusion injury by promoting regeneration and protecting mitochondria.
Ma Y, Liu T, Li P, Cao L, Lu X, Wang H
Stem cell research & therapy 2025 Jul 15;16(1):361
Stem cell research & therapy 2025 Jul 15;16(1):361
Kushenol I combats ulcerative colitis via intestinal barrier preservation and gut microbiota optimization.
He XD, Li M, Zuo XD, Ni HY, Han YX, Hu YK, Yu J, Yang XX
World journal of gastroenterology 2025 Jul 14;31(26):105656
World journal of gastroenterology 2025 Jul 14;31(26):105656
Negative Air Ions Attenuate Nicotine-Induced Vascular Endothelial Dysfunction by Suppressing AP1-Mediated FN1 and SPP1.
Xiao S, Wei T, Xiao M, Shan M, An Z, Li N, Zhou J, Zhao S, Lu X
Antioxidants (Basel, Switzerland) 2025 Jul 14;14(7)
Antioxidants (Basel, Switzerland) 2025 Jul 14;14(7)
Selenium binding protein 1 (SBP1) suppresses fructose-induced metabolic dysfunction-associated steatotic liver disease.
Koga T, Hiromura M, Song Y, Zhao S, Hirao-Suzuki M, Takeda S, Ishii Y, Ishida T, Toda A, Soeda F
Biochemical and biophysical research communications 2025 Jul 12;770:152013
Biochemical and biophysical research communications 2025 Jul 12;770:152013
Alleviation of fibrosis and oxidative stress in pressure overload-induced cardiac remodeling and heart failure via SIRT3 activation by colchicine.
Wu M, Chen G, Peng Y, Luo S
Biochemical and biophysical research communications 2025 Jul 12;770:151957
Biochemical and biophysical research communications 2025 Jul 12;770:151957
The Antidiabetic Mechanisms of Cinnamon Extract: Insights from Network Pharmacology, Gut Microbiota, and Metabolites.
Wang R, Yang K, Liu X, Zhang Y, Chen Y, Wang N, Yu L, Liu S, Hu Y, Qin B
Current issues in molecular biology 2025 Jul 12;47(7)
Current issues in molecular biology 2025 Jul 12;47(7)
Construction of a macrophage-related prognostic signature and assessment of immune checkpoint inhibitor efficacy of HCC.
Zang S, Chen H, Han Y, Cui D, Yu J
Scientific reports 2025 Jul 11;15(1):25065
Scientific reports 2025 Jul 11;15(1):25065
Beta sitosterol inhibits the proliferation and migration of synoviocytes in rheumatoid arthritis via lactylation of GPI.
Tan Y, Zhong X, He X, Yuan Y, Deng Y, Huang J, Zhou Y, Xie C, Peng H
Scientific reports 2025 Jul 11;15(1):25045
Scientific reports 2025 Jul 11;15(1):25045
Tanshinone IIA induces oxidative stress in trophoblast cells and enhances copper dependent death.
Du J, Wang X, Zeng Y, Feng J, Yang L, Huang Y, Deng G
Scientific reports 2025 Jul 11;15(1):25012
Scientific reports 2025 Jul 11;15(1):25012
Pharmacological evaluation of physcion as a TRPV1 inhibitor with multimodal analgesic efficacy in experimental pain models.
Chen H, Li G, Deng L, Li S, Huang S, Lee SM, Nie X, Bian JS
Biological research 2025 Jul 10;58(1):48
Biological research 2025 Jul 10;58(1):48
Transformable albumin-based nanocapsules selectively amplify tumor starvation and disulfidptosis through metabolic deception.
Li Y, Lu Y, Lu W, Zhong N, Li N, Xu Z, Zhang J, Sun H, Wu F, Teng Z, Tang Y, Wang S
Journal of controlled release : official journal of the Controlled Release Society 2025 Jul 10;383:113739
Journal of controlled release : official journal of the Controlled Release Society 2025 Jul 10;383:113739
Mesenchymal stem cell-secreted KGF ameliorates acute lung injury via the Gab1/ERK/NF-κB signaling axis.
Xin S, Ding Y, Yu T, Fu Y, Cui Y, Nie H
Cellular & molecular biology letters 2025 Jul 10;30(1):79
Cellular & molecular biology letters 2025 Jul 10;30(1):79
MTMR14 depletion aggravates intrapulmonary inflammation and emphysema in experimental COPD through activating macrophage M1 polarization.
Zhang J, Zhan Y, Deng Z, Chen S, Yang R, Zhang Y, Fu H, Huang Q, Wu J, Gu Y, Xie J
Respiratory research 2025 Jul 10;26(1):238
Respiratory research 2025 Jul 10;26(1):238
Neutrophil membrane-coated circular RNA nanoparticles for targeted immunotherapy in HER2-positive breast cancer brain metastasis.
Liu Y, He W, Li X, Lu X, Wu C, Gao Y, Fan D, Dong C, Zhao H
Cell communication and signaling : CCS 2025 Jul 10;23(1):333
Cell communication and signaling : CCS 2025 Jul 10;23(1):333
In vivo CRISPR screening identifies POU3F3 as a novel regulator of ferroptosis resistance in hepatocellular carcinoma via retinoic acid signaling.
Tian Y, Bao X, Lei S, Huang Y, Wang X, Tu Y, He Q, Zhang F, Xu H, Ashrafizadeh M, Sethi G, Wang F, Zeng Z
Cell communication and signaling : CCS 2025 Jul 10;23(1):329
Cell communication and signaling : CCS 2025 Jul 10;23(1):329
TRIM29 alleviates intervertebral disc degeneration through the PI3K/AKT/mTOR pathway.
Yang Q, Feng J, Xu H, Kang T, Wei Q, Jiang H
Scientific reports 2025 Jul 10;15(1):24797
Scientific reports 2025 Jul 10;15(1):24797
Taurine Attenuates Disuse Muscle Atrophy Through Modulation of the xCT-GSH-GPX4 and AMPK-ACC-ACSL4 Pathways.
Liu X, Chen Y, Zhang L, Qi Z, Yang L, Huang C, Wang L, Lin D
Antioxidants (Basel, Switzerland) 2025 Jul 10;14(7)
Antioxidants (Basel, Switzerland) 2025 Jul 10;14(7)
Fragaria orientalis attenuates hepatic fibrosis through modulation of FXR/CYP7A1, ERK/p38 MAPK, and TLR4/MyD88/NF-κB signaling in rats.
Zhang CL, Yang HY, Yi JL, Song MK, Yu ZD, Huang JY, Yi LT, Li M, Zhu JX
The Journal of pharmacy and pharmacology 2025 Jul 1;77(7):922-932
The Journal of pharmacy and pharmacology 2025 Jul 1;77(7):922-932
miR-92a-1-5p targets MEF2A to induce insulin resistance in myocardial ischemia/reperfusion injury.
Zhou AQ, Cao Y, Song YN, Zhang BF, Chen KY, Yang SY, Chen HJ
Biochemical and biophysical research communications 2025 Jul 1;768:151938
Biochemical and biophysical research communications 2025 Jul 1;768:151938
Trim65 mitigates doxorubicin-induced myocardial injury by reducing ferroptosis.
Ma X, Chen W, Hu Z, Xie L, Li Z, Liu H, Li Z, Jiang Z, Huang J, Jiang C, Huang K, Xiao S
Experimental cell research 2025 Jul 1;450(1):114613
Experimental cell research 2025 Jul 1;450(1):114613
TFE3-mediated lysosomal biogenesis and homeostasis alleviates arsenic-induced lysosomal and immune dysfunction in macrophages.
Xu G, Chen H, Cong Z, Zhou L, Zhao N, Yang Y, Li T, Liu X, Wang Y, Li B
Ecotoxicology and environmental safety 2025 Jul 1;299:118374
Ecotoxicology and environmental safety 2025 Jul 1;299:118374
Maternal lead exposure impairs offspring growth and intestinal microbiota via AMPK/ULK1 pathway activation.
He Y, Wang M, An M, Kulyar MF, Li M, Xu H, Wang Y
Ecotoxicology and environmental safety 2025 Jul 1;299:118345
Ecotoxicology and environmental safety 2025 Jul 1;299:118345
Bioinformatics identification of key microRNA-correlated genes associated with hepatocellular carcinoma heterogeneity and prognosis.
Su G, Li Y, Wang J, Liu S, Pan G, Zhan D
BMC gastroenterology 2025 Jul 1;25(1):452
BMC gastroenterology 2025 Jul 1;25(1):452
Self-reinforced piezoelectric chip for scaffold-free repair of critical-sized bone defects.
Li W, Mo Y, Xie S, Fu L, Ye Y, Zhou Y, Lai J, Wang W, Lu Y, Li G, Tian J
Nature communications 2025 Jul 1;16(1):5800
Nature communications 2025 Jul 1;16(1):5800
Prominin-2/FBXO22/BACH1 axis protects bone marrow mesenchymal stem cells against TBHP-induced ferroptosis and ameliorates intervertebral disc degeneration.
Xu Y, Zhang L, Ji M, Lu J
Stem cell research & therapy 2025 Jul 1;16(1):340
Stem cell research & therapy 2025 Jul 1;16(1):340
Identification of a ferroptosis related genes signature and GDF15 contributing to a new perspective for the diagnosis of CRPC.
Shao Y, Li X, Liu J, Qiu Z, Zhang T, Li N, Hu J, Lu F, Zhu Z
Scientific reports 2025 Jul 1;15(1):21624
Scientific reports 2025 Jul 1;15(1):21624
Phochinenin I, a Bioactive Constituent from Pholidota chinensis, Attenuates Inflammatory Response and Oxidative Stress In Vitro and In Vivo.
Li Y, Ren G, Wang W, Li H, Li A, Wang Y
ACS omega 2025 Jul 1;10(25):26488-26499
ACS omega 2025 Jul 1;10(25):26488-26499
Excessive accumulation of thioredoxin promotes osteogenic differentiation of mesenchymal stem cells of ligament in ankylosing spondylitis by upregulating autophagy levels.
Qiao J, Zhou B, Han C, Xu Q, Feng X, Xu W
Biochemical and biophysical research communications 2025 Jan;745:151255
Biochemical and biophysical research communications 2025 Jan;745:151255
LASP1 inhibits the formation of NETs and alleviates acute pancreatitis by stabilizing F-actin polymerization in neutrophils.
Zhang S, Wang Z, Zhang Y, Dong X, Zhu Q, Yuan C, Lu G, Gong W, Bi Y, Wang Y
Biochemical and biophysical research communications 2025 Jan;744:151134
Biochemical and biophysical research communications 2025 Jan;744:151134
PCSK9 promotes vascular neointimal hyperplasia through non-lipid regulation of vascular smooth muscle cell proliferation, migration, and autophagy.
Zhang Q, Miao M, Cao S, Liu D, Cao Z, Bai X, Yin Y, Jin S, Dong L, Zheng M
Biochemical and biophysical research communications 2025 Jan;742:151081
Biochemical and biophysical research communications 2025 Jan;742:151081
Astrocytes-Secreted WNT5B Disrupts the Blood-Brain Barrier Via ROR1/JNK/c-JUN Cascade During Meningitic Escherichia Coli Infection.
Qu X, Yang R, Tan C, Chen H, Wang X
Molecular neurobiology 2025 Jan;62(1):661-673
Molecular neurobiology 2025 Jan;62(1):661-673
Wnt5a promotes VM formation by modulating the stemness and EMT progression of prostate cancer cell.
Liu B, Li X, Wang S, Jia H, Zhang X, Dong Q, Li J
Translational oncology 2025 Jan;51:102155
Translational oncology 2025 Jan;51:102155
Characteristics of polycystic ovary syndrome rat models induced by letrozole, testosterone propionate and high-fat diets.
Hu R, Huang Y, Liu Z, Dong H, Ma W, Song K, Xu X, Wu X, Geng Y, Li F, Zhang M, Song Y
Reproductive biomedicine online 2025 Jan;50(1):104296
Reproductive biomedicine online 2025 Jan;50(1):104296
Bromocriptine sensitivity in bromocriptine-induced drug-resistant prolactinomas is restored by inhibiting FGF19/FGFR4/PRL.
Zhu Z, Hu B, Zhu D, Li X, Chen D, Wu N, Rao Q, Zhang Z, Wang H, Zhu Y
Journal of endocrinological investigation 2025 Jan;48(1):67-80
Journal of endocrinological investigation 2025 Jan;48(1):67-80
ARC protects cochlear hair cells from neomycin-induced ototoxicity via the Ras/JNK signaling pathway.
Yu X, Gao H, Zhang J, Fang Q, Kang W, Shang H, Lou X, Guan M
Toxicology letters 2025 Jan;403:111-119
Toxicology letters 2025 Jan;403:111-119
Tumor-Specific Protein Induced in Situ Self-Assembly of Peptide Drugs for Synergistic Mitochondria Disruption.
Hao Y, Hou DY, Zhou L, Fan YL, Wu XH, Liu YX, Xu YS, Song BL, Yi L, Qiao ZY, Wang H, Xu SP
Advanced materials (Deerfield Beach, Fla.) 2025 Jan;37(3):e2413069
Advanced materials (Deerfield Beach, Fla.) 2025 Jan;37(3):e2413069
Huanglian-Renshen-Decoction Maintains Islet β-Cell Identity in T2DM Mice through Regulating GLP-1 and GLP-1R in Both Islet and Intestine.
Wu WB, Gao F, Tang YH, Wang HZ, Dong H, Lu FE, Yuan F
Chinese journal of integrative medicine 2025 Jan;31(1):39-48
Chinese journal of integrative medicine 2025 Jan;31(1):39-48
Inhibiting UGCG prevents PRV infection by decreasing lysosome-associated autophage.
Fan W, Yao C, Ma Y, Wang H, Liu P, Zhang Z, Chu B, Yang G, Wang M
International journal of biological macromolecules 2025 Jan;285:138303
International journal of biological macromolecules 2025 Jan;285:138303
Tumor-Derived GDF15 Induces Tumor Associated Fibroblast Transformation From BMSCs and Fibroblasts in Oral Squamous Cell Carcinoma.
Zhao J, Li Y, Huang Y, Su P, Nie F, Yang P, Yang C
Journal of cellular physiology 2025 Jan;240(1):e31498
Journal of cellular physiology 2025 Jan;240(1):e31498
ROS Responsive Cerium Oxide Biomimetic Nanoparticles Alleviates Calcium Oxalate Crystals Induced Kidney Injury via Suppressing Oxidative Stress and M1 Macrophage Polarization.
He Y, Peng E, Ba X, Wu J, Deng W, Huang Q, Tong Y, Shang H, Zhong Z, Liu X, Zhang Y, Ye T, Yang X, Wang K, Xie Y, Jiang K, Xia D, Chen Z, Tang K
Small (Weinheim an der Bergstrasse, Germany) 2025 Jan;21(3):e2405417
Small (Weinheim an der Bergstrasse, Germany) 2025 Jan;21(3):e2405417
Macrophage autophagy protects against acute kidney injury by inhibiting renal inflammation through the degradation of TARM1.
Huang XR, Ye L, An N, Wu CY, Wu HL, Li HY, Huang YH, Ye QR, Liu MD, Yang LW, Liu JX, Tang JX, Pan QJ, Wang P, Sun L, Xia Y, Lan HY, Yang C, Liu HF
Autophagy 2025 Jan;21(1):120-140
Autophagy 2025 Jan;21(1):120-140
Macrophage-derived amphiregulin promoted the osteogenic differentiation of chondrocytes through EGFR/Yap axis and TGF-β activation.
Wang X, Wang S, Mu H, Yang C, Dong W, Wang X, Wang J
Bone 2025 Jan;190:117275
Bone 2025 Jan;190:117275
PIEZO1 mediates matrix stiffness-induced tumor progression in kidney renal clear cell carcinoma by activating the Ca(2+)/Calpain/YAP pathway.
Zhu B, Li F, Yu J, Liang Z, Ke X, Wang Y, Song Z, Li Z, Li G, Guo Y
Biochimica et biophysica acta. Molecular cell research 2025 Jan;1872(1):119871
Biochimica et biophysica acta. Molecular cell research 2025 Jan;1872(1):119871
Ingenane diterpenoids with anti-inflammatory activity from Euphorbia antiquorum.
Ma RF, Wu Q, Pan YP, Liu H, Zhuang XC, Zhang H
Fitoterapia 2025 Jan;180:106350
Fitoterapia 2025 Jan;180:106350
EHMT2-mediated R-loop formation promotes the malignant progression of prostate cancer via activating Aurora B.
Zhang Y, Su M, Chen Y, Cui L, Xia W, Xu R, Xue D, Zhang X, Feng X
Clinical and translational medicine 2025 Jan;15(1):e70164
Clinical and translational medicine 2025 Jan;15(1):e70164
Free fatty acid receptor-4 regulates T-cell-mediated allogeneic reaction through activating an aryl hydrocarbon receptor pathway.
Duah M, Zheng F, Shen J, Xu Y, Cao S, Yan Z, Lan Q, Wang Y, Xu K, Pan B
Acta pharmaceutica Sinica. B 2025 Jan;15(1):224-238
Acta pharmaceutica Sinica. B 2025 Jan;15(1):224-238
Sappanone A alleviates metabolic dysfunction-associated steatohepatitis by decreasing hepatocyte lipotoxicity via targeting Mup3 in mice.
Zhu A, Yan X, Chen M, Lin Y, Li L, Wang Y, Huang J, He J, Yang M, Hua W, Chen K, Qi J, Zhou Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156341
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156341
Downregulation of cardiac inflammation via the CaMKII δ/NF-κB pathway in heart failure by Lonicerae Japonicae Flos and Angelicae Sinensis Radix.
Tang J, Li X, Yu X, Wang D, Huang K, Pu H, Yu J, Li S, Wang W, Liu B, Guo S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156326
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156326
Asiaticoside alleviated NAFLD by activating Nrf2 and inhibiting the NF-κB pathway.
Wei Y, Zhang Y, Zhan B, Wang Y, Cheng J, Yu H, Lv M, Zhang Y, Zhai Y, Guan Y, Feng H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156317
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156317
Ginsenoside RK3 inhibits glioblastoma by modulating macrophage M2 polarization via the PPARG/CCL2 axis.
Zhang H, Hu J, Zhao X, Zheng B, Han Y, Luo G, Dou D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156271
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156271
Multi-omics analysis reveals the protective effects of Chinese yam polysaccharide against cisplatin-induced renal interstitial fibrosis.
Wei M, Chen S, Huang Z, Zhang P, Yang Y, Chen S, Wan P, Huang Z, Chen X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156200
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156200
The double face of licorice-kansui herb pair: Cure or curse, depending on the combining ratio and mediated by hydrogen sulfide.
Li N, Xue W, Wang C, Fan X, Yu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:155692
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:155692
Phlorizin ameliorates cognitive and behavioral impairments via the microbiota-gut-brain axis in high-fat and high-fructose diet-induced obese male mice.
Zhang S, Wang X, Liu S, Hu C, Meng Y
Brain, behavior, and immunity 2025 Jan;123:193-210
Brain, behavior, and immunity 2025 Jan;123:193-210
Nanodrug-Engineered Exosomes Achieve a Jointly Dual-Pathway Inhibition on Cuproptosis.
Sun H, Zou Y, Chen Z, He Y, Ye K, Liu H, Qiu L, Zhang Y, Mai Y, Chen X, Mao Z, Wang W, Yi C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jan;12(4):e2413408
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jan;12(4):e2413408
Cupric Doping Hollow Prussian Blue Nanoplatform for Enhanced Cholesterol Depletion: a Promising Strategy for Breast Cancer Therapy and Metastasis Inhibition.
Yan S, Xue P, Sun Y, Bai T, Shao S, Zeng X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jan;12(3):e2409967
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jan;12(3):e2409967
Knockdown of integrin β1 inhibits proliferation and promotes apoptosis in bladder cancer cells.
Wang JF, Wang JS, Liu Y, Ji B, Ding BC, Wang YX, Ren MH
BioFactors (Oxford, England) 2025 Jan-Feb;51(1):e2150
BioFactors (Oxford, England) 2025 Jan-Feb;51(1):e2150
Elevated-c-MYC-expressing Fibrosarcoma Cells With Acquired Gemcitabine Resistance Remain Sensitive to Recombinant Methioninase: A Potential Clinical Strategy for a Recalcitrant Disease.
Morinaga S, Han Q, Mizuta K, Kang BM, Bouvet M, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Higuchi T, Tsuchiya H, Demura S, Hoffman RM
Cancer diagnosis & prognosis 2025 Jan-Feb;5(1):8-14
Cancer diagnosis & prognosis 2025 Jan-Feb;5(1):8-14
Gboxin Induced Apoptosis and Ferroptosis of Cervical Cancer Cells by Promoting Autophagy-Mediated Inhibition of Nrf2 Signaling Under Low-Glucose Conditions.
Liu W, Lu J, Li J, Wang L, Chen Y, Wu Y, Zhang Z, Zhang J, Gao F, Jia C, Bao Y, Yang X, Song Z
International journal of molecular sciences 2025 Jan 9;26(2)
International journal of molecular sciences 2025 Jan 9;26(2)
Network pharmacology uncovers that secoisolariciresinol diglucoside ameliorate premature ovarian insufficiency via PI3K/Akt pathway.
Zhang Y, Liu X, Zheng Z, Huang H, Wang Y, Wu S, Shu Y, Yang Y, Zhong Y, Liao P, Wang Y, Pan Z
Scientific reports 2025 Jan 9;15(1):1493
Scientific reports 2025 Jan 9;15(1):1493
Chemerin-9 is neuroprotective in APP/PS1 transgenic mice by inhibiting NLRP3 inflammasome and promoting microglial clearance of Aβ.
Zhang J, Zhang Y, Liu L, Zhang M, Zhang X, Deng J, Zhao F, Lin Q, Zheng X, Fu B, Zhao Y, Wang X
Journal of neuroinflammation 2025 Jan 8;22(1):5
Journal of neuroinflammation 2025 Jan 8;22(1):5
Alantolactone mitigates the elevation of blood pressure in mice induced by angiotensin II by inhibiting calcium channel activation.
Yuan R, Gao M, Xu H, Liang Q, Qian L, Wang Y, Zhang H, Qiang E, Yun W
BMC cardiovascular disorders 2025 Jan 6;25(1):7
BMC cardiovascular disorders 2025 Jan 6;25(1):7
Neutrophil membrane-coated nanoparticles for targeted delivery of toll-like receptor 4 siRNA ameliorate LPS-induced acute lung injury.
Cao L, Du M, Cai M, Feng Y, Miao J, Sun J, Song J, Du B
International journal of pharmaceutics 2025 Jan 5;668:124960
International journal of pharmaceutics 2025 Jan 5;668:124960
Astragaloside IV plays a neuroprotective role by promoting PPARγ in cerebral ischemia-reperfusion rats.
Ding Y, Jie K, Xin L, Shao B
Behavioural brain research 2025 Jan 5;476:115267
Behavioural brain research 2025 Jan 5;476:115267
Puerarin pretreatment provides protection against myocardial ischemia/reperfusion injury via inhibiting excessive autophagy and apoptosis by modulation of HES1.
Yuan Y, Lai S, Hu T, Hu F, Zou C, Wang X, Fang M, Liu J, Huang H
Scientific reports 2025 Jan 4;15(1):794
Scientific reports 2025 Jan 4;15(1):794
Astragali Radix-Angelicae Sinensis Radix inhibits the activation of vascular adventitial fibroblasts and vascular intimal proliferation by regulating the TGF-β1/Smad2/3 pathway.
Li W, Xu S, Chen L, Tan W, Deng N, Li Y, Zhang W, Deng C
Journal of ethnopharmacology 2025 Jan 31;340:119302
Journal of ethnopharmacology 2025 Jan 31;340:119302
Saffron extract alleviates D-gal-induced late-onset hypogonadism by activating the PI3K-Akt-Nrf2 signaling pathway.
Liu H, Guo Z, Zang Z, Jia B, Zhou Y, Zhang H, Fu Q
Journal of ethnopharmacology 2025 Jan 31;340:119273
Journal of ethnopharmacology 2025 Jan 31;340:119273
6-Shogaol attenuates cisplatin induced emesis by inhibiting the mtDNA-cGAS-STING signaling pathway in a rat pica model.
Kan S, Ye B, Wang Y, Mo Z, Chen W, Zheng J, Zhai Y, Nie K
Journal of ethnopharmacology 2025 Jan 31;340:119251
Journal of ethnopharmacology 2025 Jan 31;340:119251
Nociceptor-localized KCC2 suppresses brachial plexus avulsion-induced neuropathic pain and related central sensitization.
Xian H, Guo H, Liu YY, Ma SB, Zhao R, Zhang JL, Zhang H, Xie RG, Guo XC, Ren J, Wu SX, Luo C, Cong R
Cell & bioscience 2025 Jan 31;15(1):12
Cell & bioscience 2025 Jan 31;15(1):12
Mechanistic insights into Suanzaoren Decoction's improvement of cardiac contractile function in anxiety-induced cardiac insufficiency.
Zhang Y, Jin Y, Zhao N, Wang T, Wang X, Li Z, Yan Y
Journal of ethnopharmacology 2025 Jan 30;337(Pt 2):118860
Journal of ethnopharmacology 2025 Jan 30;337(Pt 2):118860
Dehydrocorydaline attenuates myocardial ischemia-reperfusion injury via the FoXO signalling pathway: A multimodal study based on network pharmacology, molecular docking, and experimental study.
Li H, Yang W, Shang Z, Lu Y, Shen A, Chen D, Lin G, Li M, Li R, Wu M, Guo Z, Qu H, Fu C, Yu Z, Chen K
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118738
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118738
Therapeutic potential of Rosa roxburghii folium extract in insomnia treatment: a comprehensive evaluation of behavioral and neurochemical effects in a PCPA-induced mouse model.
He F, Yan Y, Peng M, Gao M, Zhou L, Chen F, Yang L, Li L, Yang X
Journal of the science of food and agriculture 2025 Jan 30;105(2):1044-1056
Journal of the science of food and agriculture 2025 Jan 30;105(2):1044-1056
The histone demethylase KDM5C enhances the sensitivity of acute myeloid leukemia cells to lenalidomide by stabilizing cereblon.
Zou L, Cao D, Sun Q, Yu W, Li B, Xu G, Zhou L
Cellular & molecular biology letters 2025 Jan 29;30(1):14
Cellular & molecular biology letters 2025 Jan 29;30(1):14
Dual-mode-driven nanomotors targeting inflammatory macrophages for the MRI and synergistic treatment of atherosclerosis.
Wei M, Jiang Q, Bian S, Chang P, Li B, Shi C, Zhu Y, Wang Y, Hou P, Li J
Journal of nanobiotechnology 2025 Jan 29;23(1):54
Journal of nanobiotechnology 2025 Jan 29;23(1):54
Transketolase attenuates the chemotherapy sensitivity of glioma cells by modulating R-loop formation.
Fu M, Zhang M, Zhang L, Feng Y, Gao C, Xu H, Zhang J, Zhang H, Peng T, Chu Y, Wu Y, Wang P, Ye D, Mao Y, Hua W
Cell reports 2025 Jan 28;44(1):115142
Cell reports 2025 Jan 28;44(1):115142
The regulatory role of the Netrin-1/UNC5H3 pathway in neuronal pyroptosis after stroke.
Zhai Z, Huang Z, Huang K, Zhong Y, You H, Tao E, Yang Y
International immunopharmacology 2025 Jan 27;146:113939
International immunopharmacology 2025 Jan 27;146:113939
Interleukin 8 exacerbates age-related hearing loss through regulating perivascular-resident macrophage-like melanocytes viability and the permeability of the endothelial cells.
Chen S, Zhou Y, Wu J, Lin J, Hong Z, Wang Y, Han Y, Luo X
International immunopharmacology 2025 Jan 27;146:113820
International immunopharmacology 2025 Jan 27;146:113820
Dihydromyricetin ameliorates neurotoxicity induced by high glucose through restraining ferroptosis by inhibiting JNK-inflammation pathway in HT22 cells.
Peng LT, Li MW, Song ZJ, Li Q, Zhan KB, Yan CQ, Ling HY
Neuroscience 2025 Jan 26;565:40-51
Neuroscience 2025 Jan 26;565:40-51
The RNA Demethyltransferase FTO Regulates Ferroptosis in Major Depressive Disorder.
Meng K, Liu Z, Yu Y, Zhang E, Yu X, Meng P, Xiu J
International journal of molecular sciences 2025 Jan 26;26(3)
International journal of molecular sciences 2025 Jan 26;26(3)
MC-LR induces and exacerbates Colitis in mice through the JAK1/STAT3 pathway.
Zhou X, Yang Y, Yan C, Feng S, Zhan C
Journal of toxicology and environmental health. Part A 2025 Jan 26;:1-11
Journal of toxicology and environmental health. Part A 2025 Jan 26;:1-11
Antigen B from Echinococcus granulosus regulates macrophage phagocytosis by controlling TLR4 endocytosis in immune thrombocytopenia.
Zhang Y, Yue Y, Cheng Y, Jiao H, Yan M
Chemico-biological interactions 2025 Jan 25;406:111350
Chemico-biological interactions 2025 Jan 25;406:111350
Icaritin alleviates motor impairment and osteoporosis in Parkinson's disease mice via the ER-PI3K/Akt pathway.
Lin X, Zhou X, Liu X, Xia L, Cai J, Huang N, Luo Y, Wu W
Scientific reports 2025 Jan 25;15(1):3190
Scientific reports 2025 Jan 25;15(1):3190
Intermittent Fasting Improves Sevoflurane-Induced Cognitive Dysfunction in Rats Through SIRT1-Mediated Autophagy.
Sun FW, Tian Y
Neurochemical research 2025 Jan 20;50(1):81
Neurochemical research 2025 Jan 20;50(1):81
Idebenone Protects Photoreceptors Impaired by Oxidative Phosphorylation Disorder in Retinal Detachment.
Wang L, Zou G, Yan Y, Shi R, Guo Y, Zhang M, Lu L, Dong K
Investigative ophthalmology & visual science 2025 Jan 2;66(1):17
Investigative ophthalmology & visual science 2025 Jan 2;66(1):17
Bifidobacterium breve synergizes with Akkermansia muciniphila and Bacteroides ovatus to antagonize Clostridioides difficile.
Li Y, Rui W, Sheng X, Deng X, Li X, Meng L, Huang H, Yang J
The ISME journal 2025 Jan 2;19(1)
The ISME journal 2025 Jan 2;19(1)
L3MBTL3 and STAT3 collaboratively upregulate SNAIL expression to promote metastasis in female breast cancer.
Xiao J, Wang J, Li J, Xiao J, Liu C, Tan L, Tu Y, Yang R, Pei Y, Wang M, Wong J, Zhou BP, Li J, Feng J
Nature communications 2025 Jan 2;16(1):231
Nature communications 2025 Jan 2;16(1):231
Bi-allelic variants in DAP3 result in reduced assembly of the mitoribosomal small subunit with altered apoptosis and a Perrault-syndrome-spectrum phenotype.
Smith TB, Kopajtich R, Demain LAM, Rea A, Thomas HB, Schiff M, Beetz C, Joss S, Conway GS, Shukla A, Yeole M, Radhakrishnan P, Azzouz H, Ben Chehida A, Elmaleh-Bergès M, Glasgow RIC, Thompson K, Oláhová M, He L, Jenkinson EM, Jahic A, Belyantseva IA, Barzik M, Urquhart JE, O'Sullivan J, Williams SG, Bhaskar SS, Carrera S, Blakes AJM, Banka S, Yue WW, Ellingford JM, Houlden H, DDD Study, Munro KJ, Friedman TB, Taylor RW, Prokisch H, O'Keefe RT, Newman WG
American journal of human genetics 2025 Jan 2;112(1):59-74
American journal of human genetics 2025 Jan 2;112(1):59-74
Clinical significance and pro-oncogenic function of DBF4 in clear cell renal cell carcinoma.
Chen L, Wu L, Tang M, Cheng Y, Wang K, Zhang J, Deng W, Zhu L, Chen J
BMC urology 2025 Jan 16;25(1):8
BMC urology 2025 Jan 16;25(1):8
IFNγ regulates ferroptosis in KFs by inhibiting the expression of SPOCD1 through DNMT3A.
Wang X, Yang Y, Zhou X, Yu S, Luo X, Lu L, Gao Z, Yang J
Cell death discovery 2025 Jan 16;11(1):9
Cell death discovery 2025 Jan 16;11(1):9
The therapeutic potential of Osmundacetone for rheumatoid arthritis: Effects and mechanisms on osteoclastogenesis.
Wang Z, Liu Y, Feng C, Li T, Xu H, Ding Y, Liu W, Pu L, Li R, Ai C, Chen Z, Wang X
European journal of pharmacology 2025 Jan 15;987:177135
European journal of pharmacology 2025 Jan 15;987:177135
RFWD2 increases proliferation and CDDP resistance of osteosarcoma cells.
Liu P, Xie N
Gene 2025 Jan 15;933:148973
Gene 2025 Jan 15;933:148973
Targeting METTL8 with Rabdosiin overcomes lenvatinib resistance in hepatocellular carcinoma.
Liu Y, Chen M, Wang XX, Gao Y, Han X, Wang S, Zhang W, Lei X, Yu P, Liu L, Zhang HM, Zhang K
Experimental cell research 2025 Jan 15;444(2):114389
Experimental cell research 2025 Jan 15;444(2):114389
Prolonged tamoxifen treatment induces iron deposition and ferroptosis in the liver.
Yang J, Wang D, Wang W, Wu C, Li C, Shi W, Qian J, Xie F, Shen H, Tang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jan 15;39(1):e70313
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jan 15;39(1):e70313
A multidimensional pan-cancer analysis of NDUFA4L2 and verification of the oncogenic value in colon cancer.
Yi J, Gao W, Wu C, Yang R, Yu C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jan 15;39(1):e70300
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jan 15;39(1):e70300
Cardiotoxicity of polystyrene nanoplastics and associated mechanism of myocardial cell injury in mice.
Xiong Z, Kong Q, Hua J, Chen Q, Wang D
Ecotoxicology and environmental safety 2025 Jan 15;290:117712
Ecotoxicology and environmental safety 2025 Jan 15;290:117712
Protective effects of Notoginsenoside R2 on reducing lipid accumulation and mitochondrial dysfunction in diabetic nephropathy through regulation of c-Src.
Guo X, Yang L, An X, Hu M, Shen Y, Wang N, Xu Y, Gui D
Chinese medicine 2025 Jan 15;20(1):10
Chinese medicine 2025 Jan 15;20(1):10
Two Small Peptides from Buthus martensii Hydrolysates Exhibit Antitumor Activity Through Inhibition of TNF-α-Mediated Signal Transduction Pathways.
Zhu M, Zhang S, Tang J, Hou H, Wang L, Lin H, Zhang X, Jin M
Life (Basel, Switzerland) 2025 Jan 15;15(1)
Life (Basel, Switzerland) 2025 Jan 15;15(1)
EIF4A3-Mediated circ_0008126 Inhibits the Progression and Metastasis of Gastric Cancer by Modulating the APC/β-Catenin Pathway.
Wang Z, Chen W, Wang Z, Dai X
Cancers 2025 Jan 14;17(2)
Cancers 2025 Jan 14;17(2)
Deapioplatycodin D inhibits glioblastoma cell proliferation by inducing BNIP3L-mediated incomplete mitophagy.
Sun Y, Zhu G, Zhao R, Li Y, Li H, Liu Y, Jin N, Li X, Li Y, Liu T
Cancer cell international 2025 Jan 13;25(1):11
Cancer cell international 2025 Jan 13;25(1):11
Blockade of TIPE2-Mediated Ferroptosis of Myeloid-Derived Suppressor Cells Achieves the Full Potential of Combinatory Ferroptosis and Anti-PD-L1 Cancer Immunotherapy.
Tariq HK, Liang Z, Rabiu L, Ibrahim A, Mohamady Farouk Abdalsalam N, Li R, Yang Q, Wan X, Yan D
Cells 2025 Jan 13;14(2)
Cells 2025 Jan 13;14(2)
Identification of Novel 58-5p and SREBF1 Interaction and Effects on Apoptosis of Ovine Ovarian Granulosa Cell.
Yang R, Wang Y, Yue S, Liu Y, Zhang Y, Duan C
International journal of molecular sciences 2025 Jan 11;26(2)
International journal of molecular sciences 2025 Jan 11;26(2)
Molecule interacting with CasL-2 enhances tumor progression and alters radiosensitivity in cervical cancer.
Teng Y, Zhao H, Xue G, Zhang G, Huang Y, Guo W, Zou K, Zou L
Journal of translational medicine 2025 Jan 11;23(1):44
Journal of translational medicine 2025 Jan 11;23(1):44
Dentin tubules as a long-term sustained release carrier to accelerate bone repair by loading FTY720.
Xie J, Huang H, Xu S, Zhou K, Chen X, Fang J, Zhao F
Journal of controlled release : official journal of the Controlled Release Society 2025 Jan 10;377:446-457
Journal of controlled release : official journal of the Controlled Release Society 2025 Jan 10;377:446-457
Pluripotent polysaccharide coordinated hydrogels remodel inflammation, neovascularization and reepithelization for efficient diabetic wound prohealing.
Zhang X, Ning F, Li Y, Lu J, He Y, Feng C, Dong CM
Journal of controlled release : official journal of the Controlled Release Society 2025 Jan 10;377:37-53
Journal of controlled release : official journal of the Controlled Release Society 2025 Jan 10;377:37-53
Semen Strychni Pulveratum and vomicine alleviate neuroinflammation in amyotrophic lateral sclerosis through cGAS-STING-TBK1 pathway.
Zhan Y, Huang J, Tang X, Du B, Yang B
Journal of ethnopharmacology 2025 Jan 10;336:118741
Journal of ethnopharmacology 2025 Jan 10;336:118741
Human leukocyte antigen DR alpha inhibits renal cell carcinoma progression by promoting the polarization of M2 macrophages to M1 via the NF-κB pathway.
Xiong F, Wang B, Zhang H, Zhang G, Liu Y, Liu Y, Wang C
International immunopharmacology 2025 Jan 10;144:113706
International immunopharmacology 2025 Jan 10;144:113706
The protective roles of eugenol on type 1 diabetes mellitus through NRF2-mediated oxidative stress pathway.
Jiang Y, He P, Sheng K, Peng Y, Wu H, Qian S, Ji W, Guo X, Shan X
eLife 2025 Jan 10;13
eLife 2025 Jan 10;13
Selenoprotein M protects cardiac endothelial cell integrity against high-glucose stress via enhancing Parkin-mediated mitophagy.
Zhao B, Tan WL, Yu BB, Fan J, Liu C, Liu J, Liu Z
Molecular and cellular endocrinology 2025 Jan 1;595:112392
Molecular and cellular endocrinology 2025 Jan 1;595:112392
Using chondroitin sulfate lithium hydrogel for diabetic bone regeneration via regulation of macrophage polarization.
Xu C, Li W, Mao J, Liu Z, Lao A, Mao L, Gu A, Wu J, Shen A, Lin K, Liu J
Carbohydrate polymers 2025 Jan 1;347:122787
Carbohydrate polymers 2025 Jan 1;347:122787
Bleomycin pollution and lung health: The therapeutic potential of peimine in bleomycin-induced pulmonary fibrosis by inhibiting glycolysis.
Li K, Liu X, Lu R, Zhao P, Tian Y, Li J
Ecotoxicology and environmental safety 2025 Jan 1;289:117451
Ecotoxicology and environmental safety 2025 Jan 1;289:117451
Synthesis and anti-tumor activity of menthylamine derivatives: Focusing on the potent inhibitory effect of compound W8 on glioma growth.
Wu X, Zhuo Y, Liu J, He Z, Wang M, Lei W, Liang Q, Wang A, Shen Z, Chen S, Zheng S, Huang H
Bioorganic & medicinal chemistry 2025 Jan 1;117:118024
Bioorganic & medicinal chemistry 2025 Jan 1;117:118024
Therapeutic Potential of Vanillic Acid in Ulcerative Colitis Through Microbiota and Macrophage Modulation.
Zhao H, Fu X, Wang Y, Shang Z, Li B, Zhou L, Liu Y, Liu D, Yi B
Molecular nutrition & food research 2025 Feb;69(4):e202400785
Molecular nutrition & food research 2025 Feb;69(4):e202400785
Integrating Network Pharmacology and In Vitro Experimental Verification Revealing Bushenhuoxue Recipe Against Intrauterine Adhesions via PI3K-AKT Signaling Pathway.
Wang L, Zhuang L, Lu Y, Jia J, Chen C, Zhang Y, Hong Z, Wang X
Biochemical genetics 2025 Feb;63(1):686-697
Biochemical genetics 2025 Feb;63(1):686-697
USP2 Promotes the Proliferation and Inflammation of Fibroblast-Like Synovial Cells in Rheumatoid Arthritis Through Deubiquitination of TRAF2.
Liu X, Zhang G, Liu L, Xiong G, Liu J, Wei W
Biochemical genetics 2025 Feb;63(1):592-605
Biochemical genetics 2025 Feb;63(1):592-605
Involvement of Histone Acetyltransferase 1 (HAT1) in the Spermatogenesis of Non-Condensed Nuclear Sperm in Chinese Mitten Crab, Eriocheir sinensis.
Liu H, Tang Y, Sun L, Li S, Luo L, Chen Z, Li G
Biochemical genetics 2025 Feb;63(1):183-196
Biochemical genetics 2025 Feb;63(1):183-196
Rosiglitazone Promotes Oligodendrocyte Development and Myelin Formation of Repeated Neonatal Sevoflurane Exposure via PPARγ Signaling.
Cao T, Jiang S, Wang X, Huang P, Zhou L, Di L, Han S, Huang L
Molecular neurobiology 2025 Feb;62(2):2348-2361
Molecular neurobiology 2025 Feb;62(2):2348-2361
Jinlida granules alleviate podocyte apoptosis and mitochondrial dysfunction via the AMPK/PGC‑1α pathway in diabetic nephropathy.
Sun S, Yang S, Cheng Y, Fang T, Qu J, Tian L, Zhang M, Wu S, Sun B, Chen L
International journal of molecular medicine 2025 Feb;55(2)
International journal of molecular medicine 2025 Feb;55(2)
Inhibition of DNA Methyltransferase DNMT1 Reverses Th2 Response Polarisation and Alleviates Allergic Rhinitis.
Zou P, Li J, Li J, Wang J
Clinical and experimental pharmacology & physiology 2025 Feb;52(2):e70015
Clinical and experimental pharmacology & physiology 2025 Feb;52(2):e70015
T-2 toxin triggers immunotoxic effects in goats by inducing ferroptosis and neutrophil extracellular traps.
Huang J, He K, Guo X, Wang J, Hu H, Zhang X, Guo N, Wang Y, Huang W, Huang R, Liu T, Jiang X, Zhang D, Li Q, Wei Z
Toxicology and applied pharmacology 2025 Feb;495:117232
Toxicology and applied pharmacology 2025 Feb;495:117232
Neuregulin 1 improved gastric motility and reduced gastric inflammation by activating the α7nAChR through the cholinergic anti-inflammatory pathway in diabetic rats.
Cui W, Ma Y, Zhang L, Zhang L, Yao Q, Zhang J, Cheng Y, Zeng W, Liu Q, Liu F, Liang C
Toxicology and applied pharmacology 2025 Feb;495:117205
Toxicology and applied pharmacology 2025 Feb;495:117205
ATP6V1B1 regulates ovarian cancer progression and cisplatin sensitivity through the mTOR/autophagy pathway.
Mo S, Liu T, Zhou H, Huang J, Zhao L, Lu F, Kuang Y
Molecular and cellular biochemistry 2025 Feb;480(2):1013-1026
Molecular and cellular biochemistry 2025 Feb;480(2):1013-1026
Low-dose SAHA enhances CD8(+) T cell-mediated antitumor immunity by boosting MHC I expression in non-small cell lung cancer.
Dong W, He B, Cao Y, Yang R, Zhang S, Kong Y, Lu D, Zheng X, Hou Y, Zhu M, Wang C, Yu S, Cui D, Wang H, Wang B
Cellular oncology (Dordrecht, Netherlands) 2025 Feb;48(1):249-264
Cellular oncology (Dordrecht, Netherlands) 2025 Feb;48(1):249-264
Bile duct ligation impairs visual acuity in rats by ammonia- and bilirubin-induced retinal degeneration.
Yang YT, Ji MR, Lin ZJ, Li P, Wu RZ, Liu XD, Liu L
Acta pharmacologica Sinica 2025 Feb;46(2):380-392
Acta pharmacologica Sinica 2025 Feb;46(2):380-392
Network pharmacology and animal experiments revealed the protective effects of Guilong prescription on chronic prostatitis and its possible mechanisms.
Peixuan Z, Zeqi SU, Qiongyin F, Cai Z, Ting W
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2025 Feb;45(1):89-99
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2025 Feb;45(1):89-99
Involvement of mitochondrial dysfunction and oxidative stress in the nephrotoxicity induced by high-fat diet in Sprague-Dawley rats.
Zhang B, Xu J, Wang M, Yu C
Toxicology letters 2025 Feb;404:28-36
Toxicology letters 2025 Feb;404:28-36
Se-Methylselenocysteine Ameliorates DEHP-Induced Ferroptosis in Testicular Sertoli Cells via the Nrf2/GPX4 Axis.
Mao W, Liu Y, Gu W, Xu W, Liu J, Ling Q, Wang J
Environmental toxicology 2025 Feb;40(2):191-203
Environmental toxicology 2025 Feb;40(2):191-203
Isoliquiritigenin Exhibits Anti-Inflammatory Responses in Acute Lung Injury by Covalently Binding to the Myeloid Differentiation Protein-2 Domain.
Yang L, Nie H, Du Y, Liu X, Cai B, Li J
Phytotherapy research : PTR 2025 Feb;39(2):922-937
Phytotherapy research : PTR 2025 Feb;39(2):922-937
PGAM5 promotes RIPK1-PANoptosome activity by phosphorylating and activating RIPK1 to mediate PANoptosis after subarachnoid hemorrhage in rats.
Jiajia D, Wen Y, Enyan J, Xiaojian Z, Zhen F, Jia Z, Jikai W, Xiaoxin Y, Aihua L, Fangen K, Fei L
Experimental neurology 2025 Feb;384:115072
Experimental neurology 2025 Feb;384:115072
Activation of PAR1 contributes to ferroptosis of Schwann cells and inhibits regeneration of myelin sheath after sciatic nerve crush injury in rats via Hippo-YAP/ACSL4 pathway.
Wu Z, Sun J, Liao Z, Sun T, Huang L, Qiao J, Ling C, Chen C, Zhang B, Wang H
Experimental neurology 2025 Feb;384:115053
Experimental neurology 2025 Feb;384:115053
HSP90 stabilizes visual cycle retinol dehydrogenase 5 in the endoplasmic reticulum by inhibiting its degradation during autophagy.
Jia X, Wang Y, Jiang M, Chen DD, Shang G, Liu B, Xue M, Lang Y, Zhou G, Dong Y, Zhang F, Peng X, Hu Y
The Journal of biological chemistry 2025 Feb;301(2):108126
The Journal of biological chemistry 2025 Feb;301(2):108126
Multifunctional drug delivery nanoparticles for combined chemotherapy/chemodynamic/photothermal therapy against colorectal cancer through synergistic cuproptosis/ferroptosis/apoptosis.
Yan X, Liu H, Guo L, Liu C, Zhang S, Wang X, Tang Y, Zhou R, Jiang X, Wang E, Gao S, Xu C
Materials today. Bio 2025 Feb;30:101427
Materials today. Bio 2025 Feb;30:101427
Geniposide Protects Against Myocardial Infarction Injury via the Restoration in Gut Microbiota and Gut-Brain Axis.
Chen J, Zhu T, Yang J, Shen M, Wang D, Gu B, Xu J, Zhang M, Hao X, Tang Z, Tong J, Du Y, Zhang B, Li H, Xu M
Journal of cellular and molecular medicine 2025 Feb;29(3):e70406
Journal of cellular and molecular medicine 2025 Feb;29(3):e70406
Taurine mechanism in preventing retinal cell damage from acute ocular hypertension through GTPBP3 regulation.
Lu W, Yang Y, Gao S, Wu J, Sun X
Experimental eye research 2025 Feb;251:110222
Experimental eye research 2025 Feb;251:110222
Effects of atropine on choroidal hemodynamics and VEGFA and HIF-1α expression in form-deprivation myopia guinea pigs.
Che D, Qiao D, Lv L, Zhang Y, Cao Y, Li F, Tong S, Miao P, Zhou J
Experimental eye research 2025 Feb;251:110214
Experimental eye research 2025 Feb;251:110214
Microglia-derived Galectin-9 drives amyloid-β pathology in Alzheimer's disease.
Zhang G, Peng Q, Guo X, Pan L, Xiong M, Zhang X, Dai L, Zhang Z, Xiao T, He J, Liu M, Ke W, Zhang Z
Aging cell 2025 Feb;24(2):e14396
Aging cell 2025 Feb;24(2):e14396
DHA Improves neurodevelopmental abnormalities in offspring of gestational diabetes mellitus patients via the PPAR-γ/FATP4 pathway.
Jiang Y, Zhou X, He Z, Wei L, Zhu S, Zhang H, Zhang J, Chen Y, Du Y, Ding W, Wang S, Wang Z, Feng L
Biochemical pharmacology 2025 Feb;232:116726
Biochemical pharmacology 2025 Feb;232:116726
The effects of luteolin on orthodontic tooth movement and relapse.
Huang W, Wu H, Zheng B, Liu Y
American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 2025 Feb;167(2):232-241
American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 2025 Feb;167(2):232-241
Placental extracellular vesicles induce ovarian tumour cell death in an ex vivo explant model: Possible therapeutic potential.
Sun X, Wan J, Zhang Y, Shen Y, Tang Y, Yin Y, Chamley LW, Zhao M, Chen Q
Placenta 2025 Feb;160:20-28
Placenta 2025 Feb;160:20-28
Supramolecular prodrug inspiried by the Rhizoma Coptidis - Fructus Mume herbal pair alleviated inflammatory diseases by inhibiting pyroptosis.
Qian W, Zhang B, Gao M, Wang Y, Shen J, Liang D, Wang C, Wei W, Pan X, Yan Q, Sun D, Zhu D, Cheng H
Journal of pharmaceutical analysis 2025 Feb;15(2):101056
Journal of pharmaceutical analysis 2025 Feb;15(2):101056
Trans 10, cis 12-conjugated linoleic acid in low concentration reduces while in high concentration enhances adipocyte metabolism but effectively improves hepatic steatosis of obese mice.
Rao Y, Yu S, Liang L, Wang Q, Lu J, Wang B, Gou K
The Journal of nutritional biochemistry 2025 Feb;136:109801
The Journal of nutritional biochemistry 2025 Feb;136:109801
Hspa13 Deficiency Impaired Marginal Zone B Cells Regulatory Function and Contributed to Lupus Pathogenesis.
Xing C, Cui H, Li G, Liu X, Liu K, Wen Q, Huang X, Wang R, Song L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(8):e2413144
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(8):e2413144
Primary Cilia Formation Mediated by Hsa_Circ_0005185/OTUB1/RAB8A Complex Inhibits Prostate Cancer Progression by Suppressing Hedgehog Signaling Pathway.
Fan A, Zhang Y, Li Y, Meng W, Wu F, Pan W, Ma Z, Chen W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(8):e2411675
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(8):e2411675
In Situ Transformable Nanoparticle Effectively Suppresses Bladder Cancer by Damaging Mitochondria and Blocking Mitochondrial Autophagy Flux.
Lv Y, Song B, Yang G, Wang Y, Wu Z, Si M, Yang Z, Chen H, Liu C, Li M, Zhang Y, Qiao Z, Wang L, Xu W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(5):e2409425
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(5):e2409425
Cannabidiol alleviates the inflammatory response in rats with traumatic brain injury through the PGE (2)-EP2-cAMP-PKA signaling pathway.
Cao Y, Li H, Li J, Ling T, Yin A, Luo X, Zhou Y, Li J, Jiang H, Wang H, Yang L, Wu H, Li P
Acta biochimica et biophysica Sinica 2025 Feb 8;57(5):758-769
Acta biochimica et biophysica Sinica 2025 Feb 8;57(5):758-769
Roxadustat improves diabetic myocardial injury by upregulating HIF-1α/UCP2 against oxidative stress.
Fang T, Ma C, Yang B, Zhao M, Sun L, Zheng N
Cardiovascular diabetology 2025 Feb 7;24(1):67
Cardiovascular diabetology 2025 Feb 7;24(1):67
Hypothermia regulates mitophagy and apoptosis via PINK1/Parkin-VDAC 3 signaling pathway during oxygen-glucose deprivation/recovery injury.
Zhang L, Yang S, Cui H, Hang C, Wang X, An L, Shan Z, Liang Z, Shao R, Tang Z
Scientific reports 2025 Feb 7;15(1):4607
Scientific reports 2025 Feb 7;15(1):4607
Identification of potential targets regulating neutrophil extracellular traps in acute rejection of kidney transplantation based on transcriptomics and animal experiments.
Pei J, Weng H, Peng J, Wu M, Zhan X, Zhu G, Wang D, Pan X, An N
International immunopharmacology 2025 Feb 6;147:114008
International immunopharmacology 2025 Feb 6;147:114008
The phosphodiesterase-4 inhibitor Zl-n-91 suppresses glioblastoma growth via EGR1/PTEN/AKT pathway.
Li Y, He X, Li S, Chen S, Zhao Z, Mu Y, Zhao AZ, Zhou S, Li F
European journal of pharmacology 2025 Feb 5;988:177230
European journal of pharmacology 2025 Feb 5;988:177230
Loss of Type 2 Bone Morphogenetic Protein Receptor Activates NOD-Like Receptor Family Protein 3/Gasdermin E-Mediated Pyroptosis in Pulmonary Arterial Hypertension.
Tian XT, Peng ZY, Wu YS, Cao YY, Li XC, Li Y, Tang SY, Chen AF, Li XH
Journal of the American Heart Association 2025 Feb 4;14(3):e034726
Journal of the American Heart Association 2025 Feb 4;14(3):e034726
Global MicroRNA Profiling of HSV-1 Infected Cornea Identifies miR-329 as a Novel Regulator of Virus Infection.
Sharma P, Naqvi RA, Borase H, Kapoor D, Valverde A, Capistrano K, Yadavalli T, Naqvi AR, Shukla D
Investigative ophthalmology & visual science 2025 Feb 3;66(2):61
Investigative ophthalmology & visual science 2025 Feb 3;66(2):61
Inhibition of LRRK2 Ameliorates Aspergillus fumigatus Keratitis by Regulating STING Signaling Pathways.
Han F, Wang L, Wu J, Shen L, Li Y, Guo H, Li J
Investigative ophthalmology & visual science 2025 Feb 3;66(2):13
Investigative ophthalmology & visual science 2025 Feb 3;66(2):13
Host factor PLAC8 is required for pancreas infection by SARS-CoV-2.
Ibargüen-González L, Heller S, López-García D, Dietenberger H, Barth TF, Gallego P, Fernández-Cadenas I, Alzate-Piñol S, Crespí C, Mena-Guerrero JA, Cisneros-Barroso E, Ugalde AP, Bretones G, Steenblock C, Kleger A, DeDiego ML, Barceló C
Communications medicine 2025 Feb 3;5(1):34
Communications medicine 2025 Feb 3;5(1):34
Activity-based chemical proteomics reveals caffeic acid ameliorates pentylenetetrazol-induced seizures by covalently targeting aconitate decarboxylase 1.
Li G, Huang L, Gu D, Wang P, Yi L, Kuang W, Zhang Y, Zhang J, Liu D, Shi Q, Tang H, Sun J, Zeng G, Peng X, Wang J
Cell communication and signaling : CCS 2025 Feb 3;23(1):62
Cell communication and signaling : CCS 2025 Feb 3;23(1):62
LDHA-mediated glycolysis in stria vascularis endothelial cells regulates macrophages function through CX3CL1-CX3CR1 pathway in noise-induced oxidative stress.
Yi Y, Wu MY, Chen KT, Chen AH, Li LQ, Xiong Q, Wang XR, Lei WB, Xiong GX, Fang SB
Cell death & disease 2025 Feb 3;16(1):65
Cell death & disease 2025 Feb 3;16(1):65
Pestones A and B from a Fungus Pestalotiopsis sp. Bound to Mutant p53 and Changed Its Conformation.
Sadahiro Y, Okubo M, Hitora Y, Hitora-Imamura N, Kotani S, Tsukamoto S
Journal of natural products 2025 Feb 28;88(2):546-553
Journal of natural products 2025 Feb 28;88(2):546-553
Molecular Mechanism of Vine Tea Dihydromyricetin Extract on Alleviating Glucolipid Metabolism Disorder in db/db Mice: Based on Liver RNA-Seq and TLR4/MyD88/NF-κB Pathway.
Zhou X, Liu X, Yi Y, Chen S, Zhang Y, Fan W, Lv C, Qin S
International journal of molecular sciences 2025 Feb 28;26(5)
International journal of molecular sciences 2025 Feb 28;26(5)
Diagnostics and immunological function of CENPN in human tumors: from pan-cancer analysis to validation in breast cancer.
Jing Y, Wang Y, Li Y, Huang X, Wang J, Yelihamu D, Guo C
Translational cancer research 2025 Feb 28;14(2):881-906
Translational cancer research 2025 Feb 28;14(2):881-906
Hypoxia Promotes Gluconeogenesis Through PGC-1α in the Liver of Lasiopodomys brandtii.
Li M, Huang M, Wan J, Gao Y, Song J, Li X, Li Q, Cheng H, Shao T, Wang Z
Integrative zoology 2025 Feb 28;
Integrative zoology 2025 Feb 28;
Discovery of Novel Aromatic Urea-Imidazole Salt Derivatives for Cancer Therapy via Targeting ERK1/2.
Wang M, Yang S, Li X, Zheng Y, Bai Y, Luo W, Zhu G, Chang J, Zhu B
Journal of medicinal chemistry 2025 Feb 27;68(4):4101-4132
Journal of medicinal chemistry 2025 Feb 27;68(4):4101-4132
Deletion of Xist repeat B disrupts cell cycle and asymmetric cell division through Usp9x hyperactivation in mice.
Liang M, Zhang L, Gong H, Yang L, Wang H, Song N, Lai L, Xie W, Li Z
Nucleic acids research 2025 Feb 27;53(5)
Nucleic acids research 2025 Feb 27;53(5)
Harnessing TAGAP to improve immunotherapy for lung squamous carcinoma treatment by targeting c-Rel in CD4+ T cells.
Cai P, Sun H, Jiang T, Li H, Huang D, Hao X, Wang W, Xing W, Liang G
Cancer immunology, immunotherapy : CII 2025 Feb 25;74(4):114
Cancer immunology, immunotherapy : CII 2025 Feb 25;74(4):114
Methionine regulates maternal-fetal immune tolerance and endometrial receptivity by enhancing embryonic IL-5 secretion.
Cai S, Xue B, Li S, Wang X, Zeng X, Zhu Z, Fan X, Zou Y, Yu H, Qiao S, Zeng X
Cell reports 2025 Feb 25;44(2):115291
Cell reports 2025 Feb 25;44(2):115291
ITIH5-mediated fibroblast/macrophage crosstalk exacerbates cardiac remodelling after myocardial infarction.
Wu Y, Meng L, Zhan S, Li M, Huang J, Chen X, Chen L, Gao X, Chen H, Chen H, Zhong Y, Xu L, Xu Y
Journal of translational medicine 2025 Feb 24;23(1):224
Journal of translational medicine 2025 Feb 24;23(1):224
Hepatic Lamp2a deficiency promotes inflammation of murine autoimmune cholangitis via affecting bile acid metabolism.
Fan Q, Guo G, Hu Y, Lu Y, Su R, Yang J, Xia E, Ma S, Zhang M, Wang J, Li T, Han Y
iScience 2025 Feb 21;28(2):111804
iScience 2025 Feb 21;28(2):111804
12/15-Lipoxygenase-Derived Electrophilic Lipid Modifications in Phagocytic Macrophages.
Deng K, Isobe Y, Tsumagari K, Kato T, Arai H, Imami K, Arita M
ACS chemical biology 2025 Feb 21;20(2):357-368
ACS chemical biology 2025 Feb 21;20(2):357-368
Hypoxia-Induced VGF Promotes Cell Migration and Invasion in Prostate Cancer via the PI3K/Akt Axis.
Wang L, Zhang T, Qian Y, Wu Y, Li T, Zheng Y, Luo C, Wu X, Chen T, Ou L
Frontiers in bioscience (Landmark edition) 2025 Feb 20;30(2):25522
Frontiers in bioscience (Landmark edition) 2025 Feb 20;30(2):25522
Hesperetin alleviates PM2.5-induced lung injury by inhibiting ferroptosis in an Nrf2-dependent manner.
Wang L, Tang Y, Hou T, Gao Y, Ci X, Peng L
International immunopharmacology 2025 Feb 20;148:114123
International immunopharmacology 2025 Feb 20;148:114123
Paroxetine alleviates dendritic cell and T lymphocyte activation via GRK2-mediated PI3K-AKT signaling in rheumatoid arthritis.
Liu T, Jin C, Sun J, Zhu L, Wang C, Xiao F, Liu X, Lv L, Yang X, Zhou W, Tan C, Wang X, Wei W
Chinese medical journal 2025 Feb 20;138(4):441-451
Chinese medical journal 2025 Feb 20;138(4):441-451
Cornuside alleviates cognitive impairments induced by Aβ(1-42) through attenuating NLRP3-mediated neurotoxicity by promoting mitophagy.
Zhou F, Lian W, Yuan X, Wang Z, Xia C, Yan Y, Wang W, Tong Z, Cheng Y, Xu J, He J, Zhang W
Alzheimer's research & therapy 2025 Feb 19;17(1):47
Alzheimer's research & therapy 2025 Feb 19;17(1):47
Autism-associated ASPM variant causes macrocephaly and social-cognitive deficits in mice.
Singh S, Kim H, Ecevitoglu A, Chasse R, Ludko AM, Sanganahalli B, Gangasandra V, Park SR, Yee SP, Grady J, Salamone J, Holly Fitch R, Spellman T, Hyder F, Bae BI
bioRxiv : the preprint server for biology 2025 Feb 19;
bioRxiv : the preprint server for biology 2025 Feb 19;
A glucose-enriched lung pre-metastatic niche triggered by matrix stiffness-tuned exosomal miRNAs in hepatocellular carcinoma.
Zhao Y, Yu H, Li J, Qian J, Li M, Zhang X, Wang M, Wang Y, Dong Y, You Y, Zhou Q, Gao D, Zhao Y, Liu B, Chen R, Ren Z, Wang Z, Zhang K, Cui J
Nature communications 2025 Feb 18;16(1):1736
Nature communications 2025 Feb 18;16(1):1736
ERS regulates endometrial epithelial cell autophagy through XBP1s-mediated activation of the PI3K/AKT pathway.
Gao K, Zhao Y, Si M, Zhang B, Wang Z, Chen H, Lin P, Wang A, Jin Y
Scientific reports 2025 Feb 18;15(1):5943
Scientific reports 2025 Feb 18;15(1):5943
HSPB1 Orchestrates the Inflammation-Associated Transcriptome Profile of Atherosclerosis in HUVECs.
Zhao G, Zhao L, Miao Y, Yang L, Huang L, Hu Z
Frontiers in bioscience (Landmark edition) 2025 Feb 17;30(2):36306
Frontiers in bioscience (Landmark edition) 2025 Feb 17;30(2):36306
A novel piperine derivative HJJ_3_5 inhibits colorectal cancer progression by modulating EMT signaling pathways.
Cheng W, Liu S, He J, Li H, Liu X, Hu Z, Wang X, Wu Z, Xu G, Liu W, Liu B
Biochemical and biophysical research communications 2025 Feb 16;749:151323
Biochemical and biophysical research communications 2025 Feb 16;749:151323
CircMETTL9 targets CCAR2 to induce neuronal oxidative stress and apoptosis via mitochondria-mediated pathways following traumatic brain injury.
Huang H, Jiang NN, Lu GW, Xu F, Sun LL, Zhu J, Dong Z, Zhang ZJ, Liu S
Free radical biology & medicine 2025 Feb 16;228:44-61
Free radical biology & medicine 2025 Feb 16;228:44-61
Sulfonated albumin from hepatocytes accelerates liver fibrosis in nonalcoholic fatty liver disease through endoplasmic reticulum stress.
Liu T, Sui M, Tian M, Wu N, Zhao S, Wang Y, Yang Y, Ma S, Jiao D, Wang L, Feng Y, Zhang Y, Qin C, Liu C, Qi J, Zhu Q
Free radical biology & medicine 2025 Feb 16;228:150-162
Free radical biology & medicine 2025 Feb 16;228:150-162
FADS1 inhibition protects retinal pigment epithelium cells from ferroptosis in age related macular degeneration.
Zhang A, Wei TT, Tan X, Tan CY, Zhuang M, Xie TH, Cai J, Yao Y, Zhu L
European journal of pharmacology 2025 Feb 15;989:177227
European journal of pharmacology 2025 Feb 15;989:177227
Gestational diabetes mellitus-derived miR-7-19488 targets PIK3R2 mRNA to stimulate the abnormal development and maturation of offspring-islets.
Xu C, Zou L, Wang L, Lv W, Cao X, Jia X, Wang Y, Jiang G, Ji L
Life sciences 2025 Feb 15;363:123369
Life sciences 2025 Feb 15;363:123369
Effects of electroacupuncture on microglia phenotype and epigenetic modulation of C/EBPβ in SAMP8 mice.
Wang L, Li W, Wu W, Liu Q, You M, Liu X, Ye C, Chen J, Tan Q, Liu G, Du Y
Brain research 2025 Feb 15;1849:149339
Brain research 2025 Feb 15;1849:149339
Micheliolide attenuates sepsis-induced acute lung injury by suppressing mitochondrial oxidative stress and PFKFB3-driven glycolysis.
Li W, Li Y, Xiao L, Xie Z, Peng J, Huang W, Li X, Meng Y
Journal of translational medicine 2025 Feb 14;23(1):181
Journal of translational medicine 2025 Feb 14;23(1):181
HIF2α drives ccRCC metastasis through transcriptional activation of methylation-controlled J protein and enhanced prolegumain secretion.
Shen T, Su Y, Wang D, Li G, Liu X, Sun C, Hu T, Pang H, Mi X, Zhang Y, Yue S, Zhang Z, Tan X
Cell death & disease 2025 Feb 13;16(1):93
Cell death & disease 2025 Feb 13;16(1):93
Multi-dimensional bio mass cytometry: simultaneous analysis of cytoplasmic proteins and metabolites on single cells.
Qin S, Zhang X, Zhang Y, Miao D, Wei W, Bai Y
Chemical science 2025 Feb 12;16(7):3187-3197
Chemical science 2025 Feb 12;16(7):3187-3197
NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer's disease progression.
McManus RM, Komes MP, Griep A, Santarelli F, Schwartz S, Ramón Perea J, Schlachetzki JCM, Bouvier DS, Khalil MA, Lauterbach MA, Heinemann L, Schlüter T, Pour MS, Lovotti M, Stahl R, Duthie F, Rodríguez-Alcázar JF, Schmidt SV, Spitzer J, Noori P, Maillo A, Boettcher A, Herron B, McConville J, Gomez-Cabrero D, Tegnér J, Glass CK, Hiller K, Latz E, Heneka MT
Immunity 2025 Feb 11;58(2):326-343.e11
Immunity 2025 Feb 11;58(2):326-343.e11
Mechanism of Yinxu Weitong Capsule in the treatment of precancerous lesions of gastric cancer based on network pharmacology and experimental validation.
Wang Y, Li D, Zhao L, Liu J, Dou D, Liu N, Zhuo Y, Zhang S
Journal of ethnopharmacology 2025 Feb 11;341:119303
Journal of ethnopharmacology 2025 Feb 11;341:119303
Nano-alkaline ion-excited NETs ablative eye drops promote ocular surface recovery.
Zhang J, Zhang L, Sun Z, Li Z, Zou X, Sun S, Zhu L, Xi K, Liu Z, Deng G
Journal of controlled release : official journal of the Controlled Release Society 2025 Feb 10;378:864-879
Journal of controlled release : official journal of the Controlled Release Society 2025 Feb 10;378:864-879
Effect of Rhei Radix Et Rhizome on treatment of polycystic ovary syndrome by regulating PI3K/AKT pathway and targeting EGFR/ALB in rats.
Yang W, Qiu J, Zi J, Li Y, Li J, Guo M, Zhou Y, Yang X, Lai Y
Journal of ethnopharmacology 2025 Feb 10;338(Pt 1):119020
Journal of ethnopharmacology 2025 Feb 10;338(Pt 1):119020
The chromatin remodeler Brg1 is essential for cochlear sensory epithelium differentiation and patterning.
Song Y, Dou Z, Liu W, Zhang A, Gao X, Shi H, Zhang Z, Gao J, Jin Y
Human molecular genetics 2025 Feb 10;
Human molecular genetics 2025 Feb 10;
Preliminary exploration of the C-3 galloyl group and the B-5' hydroxyl group enhance the biological activity of catechins in alleviating obesity induced by high-fat diet in mice.
Zeng H, Peng L, Liu C, Zhou Y, Wan L, Wen S, Fang W, Yang X, Bai Q, Zeng J, Huang J, Zhang S, Liu Z
Food chemistry 2025 Feb 1;464(Pt 2):141785
Food chemistry 2025 Feb 1;464(Pt 2):141785
Transcranial alternating current stimulation inhibits ferroptosis and promotes functional recovery in spinal cord injury via the cGMP-PKG signalling pathway.
Huang K, Fang J, Xiao S, Wang W, Zhang G, Sun W, Shuai L, Bi H
Life sciences 2025 Feb 1;362:123341
Life sciences 2025 Feb 1;362:123341
Antibacterial chitosan/organic rectorite nanocomposite-conjugated gelatin/β-cyclodextrin hydrogels with improved hemostasis performance for wound repair.
Huang R, Bian Y, Wang W, Xu L, Zhang H, Zhou H, Du J, Li J, Zhang Y, Li X, Li J
Carbohydrate polymers 2025 Feb 1;349(Pt A):122961
Carbohydrate polymers 2025 Feb 1;349(Pt A):122961
Crucial roles of asprosin in cisplatin-induced ferroptosis and acute kidney injury.
Zheng F, Lei JZ, Wang JX, Xu XY, Zhou B, Ge R, Dai M, Dong HK, Wu N, Li YH, Zhu GQ, Zhou YB
Free radical biology & medicine 2025 Feb 1;227:296-311
Free radical biology & medicine 2025 Feb 1;227:296-311
β-Hydroxybutyrate-induced mitochondrial DNA (mtDNA) release mediated innate inflammatory response in bovine mammary epithelial cells by inhibiting autophagy.
Huo Y, Shen T, Feng T, Li M, Zhao W, Loor JJ, Aernouts B, Psifidi A, Xu C
Journal of animal science and biotechnology 2025 Feb 1;16(1):15
Journal of animal science and biotechnology 2025 Feb 1;16(1):15
Ginsenoside Rg1 Alleviates Hydrogen Peroxide-Induced Autophagy and Apoptosis in Ovarian Granulosa Cells.
Li X, Weng SQ, Li QH, Ji M, Zhou Y, Xiao Q, Luo T, Liu ZX
Cell biochemistry and biophysics 2025 Dec;83(4):4781-4792
Cell biochemistry and biophysics 2025 Dec;83(4):4781-4792
Effect of the Deubiquitinating Peptidase 7 (USP7) on Hepatitis B Virus (HBV) Replication and the Antiviral Efficacy of Entecavir (ETV).
Liu Y, Pei S, Wang X, Li X, Long Y, Sun S, Meng C, Feng F
Molecular biotechnology 2025 Dec;67(12):4598-4608
Molecular biotechnology 2025 Dec;67(12):4598-4608
High glucose mediates diabetic peripheral neuropathy by inducing Schwann cells apoptosis through the Dgkh/PKC-α signaling pathway.
Zuo L, Qu M, Zhang M, Cheng P, Guo M, Selvarajah D, Tesfaye S, Wu J
Acta diabetologica 2025 Dec;62(12):2109-2119
Acta diabetologica 2025 Dec;62(12):2109-2119
Expression of ORMDL1 in esophageal squamous cell carcinoma and its effect on patient outcomes: A potential biomarker and treatment target.
Wang H, Zhang W, Wang Y, Guo R, Li Y, Yi Z, Yan S, Li X, Song J
Translational oncology 2025 Dec;62:102554
Translational oncology 2025 Dec;62:102554
Integrative single-cell and spatial transcriptome analysis reveals the functions of TREM2(high) macrophages and infarct border dynamics post-myocardial infarction.
Xiong T, Chen Y, Liu C, Li Y, Zhang Y, Chang Q
Molecular and cellular biochemistry 2025 Dec;480(12):6077-6109
Molecular and cellular biochemistry 2025 Dec;480(12):6077-6109
HNRNPC-Mediated m6A Epitranscriptomics Drives CD80-Dependent Tubular Dysfunction in Sepsis-Induced AKI.
Juan C, Zhao X, Wang Y, Chen D, Yu M, Mao Y
Inflammation 2025 Dec;48(6):4591-4607
Inflammation 2025 Dec;48(6):4591-4607
Stimulator of Interferon Genes Regulates Ferroptosis and Airway Inflammation via acyl-CoA Synthetase Long-Chain Family Member 4 in Asthmatic Mice.
Chen S, Jiang X, Li X, Wang T, Yang N
Inflammation 2025 Dec;48(6):4461-4474
Inflammation 2025 Dec;48(6):4461-4474
Pharmacological Activation of GPR68 Attenuates Ferroptosis in Spinal Cord Ischemia/Reperfusion Injury Through PI3K/Akt-Mediated Nrf2 Antioxidant Pathway.
Yang R, Ye J, Wang P, Liu T, Cheng B, Li F
Inflammation 2025 Dec;48(6):4289-4301
Inflammation 2025 Dec;48(6):4289-4301
LARS1 Promotes Tubular Epithelial Cells Epithelial Mesenchymal Transition in Chronic Kidney Disease by Inhibiting Lipophagy.
Guo R, Chen MN, Lin QH, Qi HM, Wang XQ, Li BY, Wang S, Xu SJ, Zhang Y, Liu W
Inflammation 2025 Dec;48(6):4094-4109
Inflammation 2025 Dec;48(6):4094-4109
Panaxatriol saponins exert anti-renal fibrosis by suppressing TNF-α mediated inflammation and TGF-β1/Smad3 signaling pathway.
Yi S, Li F, Ma X, Xu Y, Lai W, Chen H, Fan J, Mao N, Ren S
Renal failure 2025 Dec;47(1):2516774
Renal failure 2025 Dec;47(1):2516774
Investigation of the mechanism of Yijing Decoction in the treatment of premature ovarian insufficiency: A network pharmacology study.
Xu Y, Zhao X, Yu W, Zhang P, Cheng Z, Yang L, Zhou H
Biochemistry and biophysics reports 2025 Dec;44:102331
Biochemistry and biophysics reports 2025 Dec;44:102331
Endoplasmic Reticulum Stress Exacerbates Nucleus Pulposus Cell Pyroptosis via PERK-Dependent Activation of JAK1-STAT3 Signaling.
Chen L, Zhang ZJ, Li YP, Gao JW, Shi H, Shen LJ, Zhou S, Li ML
Cell biochemistry and function 2025 Dec;43(12):e70148
Cell biochemistry and function 2025 Dec;43(12):e70148
A dual-drug sequential delivery hydrogel for programmatic microglia/macrophage polarization and function recovery in spinal cord injury.
Li Y, Liang Y, He C, Yao R, Jian K, Shi L
Materials today. Bio 2025 Dec;35:102365
Materials today. Bio 2025 Dec;35:102365
Vitamin C-functionalized copper nanozymes for treating drug-resistant intracellular infections and hyperinflammation.
Lu Y, He A, Tao J, Yang X, Wang S, Li X, Dang M, Zhang Y, Dai Z, Li Q, Dong H, Zhang X
Materials today. Bio 2025 Dec;35:102348
Materials today. Bio 2025 Dec;35:102348
Cholesterol modified defense peptide as an EMP2-siRNA delivery system for synergistic immunogene therapy against breast cancer.
Wang X, Chen S, He G, Zhu Y, Zhang N, Gong C, Li X, Chen Y
Materials today. Bio 2025 Dec;35:102321
Materials today. Bio 2025 Dec;35:102321
ANGPTL3 nanobody-FGF21 fusion protein ameliorates metabolic dysfunction-associated fatty liver disease via regulation of lipid and glucose metabolism and attenuation of oxidative stress.
Zhang Y, Hu X, Cao Z, Zhou K, Sun Y, Deng Y, Xu S, Nan Y, Gai X, Li M, Bai Y, Ge M, Ju D
International journal of biological macromolecules 2025 Dec;332(Pt 2):148726
International journal of biological macromolecules 2025 Dec;332(Pt 2):148726
ASIC1a Promotes nucleus pulposus derived stem cells apoptosis through modulation of SIRT3-dependent mitochondrial redox homeostasis in intervertebral disc degeneration.
Zhang ZG, Kang L, Zhou LP, Wang YX, Jia CY, Zhao CH, Zhang B, Wang JQ, Zhang HQ, Zhang RJ, Shen CL
Redox report : communications in free radical research 2025 Dec;30(1):2504120
Redox report : communications in free radical research 2025 Dec;30(1):2504120
Norepinephrine promotes oxidative stress in vascular adventitial fibroblasts via PKC/NFκB-mediated NOX2 upregulation.
Wang YM, Dong HK, Dai M, Wang JX, Xu XY, Zhu GQ, Li XZ
Redox report : communications in free radical research 2025 Dec;30(1):2494314
Redox report : communications in free radical research 2025 Dec;30(1):2494314
Flavonoids from Polypodium hastatum as neuroprotective agents attenuate cerebral ischemia/reperfusion injury in vitro and in vivo via activating Nrf2.
Yao H, Wu R, Du D, Ai F, Yang F, Li Y, Qi S
Redox report : communications in free radical research 2025 Dec;30(1):2440204
Redox report : communications in free radical research 2025 Dec;30(1):2440204
WDR4 drives tumour-associated macrophage reprogramming and tumour progression via selective translation and membrane cholesterol efflux.
Liu J, Qu C, Liu Y, Gongye X, Zhang M, Ma T, He W, Wang H, Chen X, Xia P, Yuan Y
Nature cell biology 2025 Dec;27(12):2152-2166
Nature cell biology 2025 Dec;27(12):2152-2166
SLX1 silencing overcomes Olaparib resistance in metastatic castration-resistant prostate cancer by disrupting SLX4-mediated DNA repair complexes.
Zhao X, Feng S, Nitie X, Muluo S, Lei Y
Cancer biology & therapy 2025 Dec;26(1):2545062
Cancer biology & therapy 2025 Dec;26(1):2545062
Knockdown of NDUFAF6 inhibits breast cancer progression via promoting mitophagy and apoptosis.
Wu S, Ma X, Zhang X, Du K, Shi C, Almaamari AA, Han B, Su S, Liu Y
Cancer biology & therapy 2025 Dec;26(1):2445220
Cancer biology & therapy 2025 Dec;26(1):2445220
UHRF1 ameliorates liver cirrhosis through suppressing macrophage M1 polarization by catalyzing HMGA2 promoter methylation.
Li R, Tao Q, Zha J, Wang S, Huang X, Wang J, Zhai H, Hong S, Zhang G
Biochemical pharmacology 2025 Dec;242(Pt 3):117357
Biochemical pharmacology 2025 Dec;242(Pt 3):117357
Sappanone A, a potential natural inhibitor of PI3K, alleviates metabolic dysfunction-associated steatohepatitis in experimental models.
Qiao X, Li Q, Fan R, Cheng Y, Zeng Q, Xue H, Zhang X, Zhang Y, Liu Y
Biochemical pharmacology 2025 Dec;242(Pt 3):117305
Biochemical pharmacology 2025 Dec;242(Pt 3):117305
Targeting TRAF6 inhibits cystogenesis in autosomal dominant polycystic kidney disease.
Ren Y, Pan Y, Zhu X, Li L, Zhao W, Fu K, Chen Y, Sun Y, Guo D
Biochemical pharmacology 2025 Dec;242(Pt 2):117222
Biochemical pharmacology 2025 Dec;242(Pt 2):117222
1275-nm Photobiomodulation Alleviates Brain Drainage Impairment as a Promising Therapeutic Strategy for Aging-Related Neurological Decline.
Lin H, Liu S, Yang Q, Li J, Wang J, Semyachkina-Glushkovskaya O, Li D, Yu T, Zhu D
Aging cell 2025 Dec;24(12):e70261
Aging cell 2025 Dec;24(12):e70261
Morin alleviates sepsis-associated encephalopathy through inhibiting ferroptosis via SIRT1.
Wu Z, Li H, Zhang X, Yang Y, Hu W, Hu B, Zou X
Brain research bulletin 2025 Dec;233:111638
Brain research bulletin 2025 Dec;233:111638
Cross-kingdom delivery and putative gene modulation of androgen pathways by plant-derived exosome-like nanoparticles from polygoni multiflori radix promotes hair growth via miRNA cargo.
Li S, Zhang Y, Liu X, Su H, Cao H, Xuan H, Cui Y, Lu Z, Zhang Q, Li Y, Liu X, Bao X, Xu H, Wang Y, Zhuo X, Zhang X, Zhang Q, Zhang L
Pharmacological research 2025 Dec;222:108033
Pharmacological research 2025 Dec;222:108033
Mdivi-1 promotes lipid droplets-mitochondria contact and ameliorates cardiac lipotoxicity in high-fat diet-fed mice.
Xu Z, Ma Z, Ren H, Yang Y, Zhao X, Zhang B
Pharmacological research 2025 Dec;222:108028
Pharmacological research 2025 Dec;222:108028
Duhuo Jisheng Decoction mitigates postmenopausal rheumatoid arthritis by suppressing eEF2K-mediated cellular senescence.
Chen D, Chen Y, Yang X, Li R, He F, Xiao Y, Quan M, Pang B, Chen X, Xian L, He X, Shu Y, Guo W, Ouyang J, Liu P, Ren H, Lu J, He J, Chen Z, Tan J, Liu L, Pan H
Pharmacological research 2025 Dec;222:108013
Pharmacological research 2025 Dec;222:108013
Activation of endogenous PRKN by structural derepression is linked to increased turnover of the E3 ubiquitin ligase.
Fiesel FC, Bustillos BA, Watzlawik JO, Chen CXQ, Berryer MH, Zhang J, Boneski PK, Hayes CS, Bredenberg JM, Deneault E, You Z, Abdien N, Aprahamian N, Goldsmith TM, Baninameh Z, Cocker LT, Zhang H, Goldberg MS, Fon EA, Trempe JF, Virdee S, Durcan TM, Springer W
Autophagy 2025 Dec;21(12):2750-2770
Autophagy 2025 Dec;21(12):2750-2770
A study on the establishment of a traumatic brain injury model of tree shrews and the observation of neuroinflammatory responses.
Yu W, Yang L, Zhang X, Zhang J, Zhang J, Wang L, Huang Y, Hong S, Chen L, Wu H, Li J
IBRO neuroscience reports 2025 Dec;19:912-918
IBRO neuroscience reports 2025 Dec;19:912-918
Matrix stiffness-sensitive LDHA drives autophagy of pancreatic ductal adenocarcinoma via inducing FOXO3 expression and lactylation.
Gong T, Han Q, Zhang Y, Zhu K, Chen Y, Tao Y, Xing H, Wu D, Ma Y, Zhang S
Biomaterials advances 2025 Dec;177:214401
Biomaterials advances 2025 Dec;177:214401
miR-196a-5p suppresses the MAPK/ERK pathway by targeting HOXA7 to regulate the proliferation and apoptosis of placental trophoblasts in gestational diabetes.
Li J, Xie X, Lu L, Gan B, Yan J
Placenta 2025 Dec;172:167-178
Placenta 2025 Dec;172:167-178
Lactobacillus delbrueckii Alleviate Oxidative Stress and Intestinal Injuries by Activating TLR2 and TLR4 Expressions in IPEC-J2 Cells.
Chen F, Wu S, Wang X, Li Y, He B, Fu Y, Huang X, Chen J
Probiotics and antimicrobial proteins 2025 Dec;17(6):5184-5194
Probiotics and antimicrobial proteins 2025 Dec;17(6):5184-5194
Time-restricted feeding promotes glucagon-like peptide-1 secretion and regulates appetite via tryptophan metabolism of gut Lactobacillus in pigs.
Li Q, Tan D, Xiong S, Yu K, Su Y, Zhu W
Gut microbes 2025 Dec;17(1):2467185
Gut microbes 2025 Dec;17(1):2467185
Gut dysbiosis-induced vitamin B6 metabolic disorder contributes to chronic stress-related abnormal behaviors in a cortisol-independent manner.
Qing W, Chen H, Ma X, Chen J, Le Y, Chen H, Tong J, Duan K, Ma D, Ouyang W, Tong J
Gut microbes 2025 Dec;17(1):2447824
Gut microbes 2025 Dec;17(1):2447824
LPS disrupts erythroid-myeloid balance in zebrafish via Jak2/Stat3-Hif1a signaling.
Yu HC, Chen MY, Zhang SL, Tong FC, Wang FP, Wang L, Zhang JL, Guo JJ, Zhang BY, Tian JQ, Wu J
Fish & shellfish immunology 2025 Dec;167:110874
Fish & shellfish immunology 2025 Dec;167:110874
Genome-scale CRISPR screen identifies host factors associated with bovine parainfluenza virus 3 infection.
Geng Y, Jiang C, Zhang H, Yang H, Peng Y, Chen Y, Hu C, Liu H, Li S, Chen H, Xie S, Guo A
Virulence 2025 Dec;16(1):2589554
Virulence 2025 Dec;16(1):2589554
MicroRNA-3473b regulates corticosterone-induced microglial polarization and inflammation through TREM2.
Shi J, Ma C, Liu Y, Yang C, Wu J, Wang X
Journal of pharmacological sciences 2025 Dec;159(4):209-218
Journal of pharmacological sciences 2025 Dec;159(4):209-218
Hypoxia-induced secretory autophagy in cancer-associated fibroblasts promotes ECM remodelling through serglycin secretion in oral squamous cell carcinoma.
Zhang Y, Tao C, Yin X, Wang Z, Zhang Y, Yu J, Wang Y, Han W
Clinical and translational medicine 2025 Dec;15(12):e70556
Clinical and translational medicine 2025 Dec;15(12):e70556
Formononetin and daidzein from Huoxiangzhengqi formula ameliorate Salmonella Typhimurium-induced intestinal flora dysbiosis and barrier dysfunction.
Li Z, Wan F, Zhang N, Xiong H, Song T, Mei Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157465
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157465
Dietary urolithin A suppresses lung cancer via gut microbiota-mediated autophagy activation.
Zhang J, Li X, Sun L, Chen B, Zhang R, Duan J
The Journal of nutritional biochemistry 2025 Dec;146:110080
The Journal of nutritional biochemistry 2025 Dec;146:110080
Adipose-derived mesenchymal stem cell exosomes protect keratinocytes from high-glucose injury by modulating KEAP1/NRF2/HO-1 axis.
Yuan Y, Song S, Xiao Y, Feng R, Li M, Zhang H, Luo L, Wang K, Wang P, Wei L, Zhang Y, Zhang B, Jiang S, Shen K, Guan H, Hu D
Cellular signalling 2025 Dec;136:112172
Cellular signalling 2025 Dec;136:112172
Melatonin attenuates lipopolysaccharide-induced acute myocardial injury by regulating KLF4 expression.
Dan Z, Liu W, Zhang H, Shi X, Zhu R, Yang M, Wang Y, Zhu H
Cellular signalling 2025 Dec;136:112080
Cellular signalling 2025 Dec;136:112080
Breast cancer cell-derived adrenomedullin confers cancer-associated adipose remodeling through the cAMP/Creb1/Zeb1 axis.
Chen X, Cao L, Feng M, Shuai Q, Guo M, Li Z, Qi C, Shi J, Liu Y, Zuo S, Yu T, Hu H, Wang Y, Xue Y, Sun P, Shi Y, Wang H, Liu L, Yang S
British journal of cancer 2025 Dec;133(12):1815-1828
British journal of cancer 2025 Dec;133(12):1815-1828
Potentiating Cerebral Perfusion Normalizes Glymphatic Dynamics in Systemic Inflammation.
Zhao R, Sun B, Wei P, Sun Y, He Q, Zhang K, Lu J, Zhu S, Yang Y, Guo Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(47):e03576
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(47):e03576
Qula-derived Limosilactobacillus fermentum TD-3 and Lactococcus lactis MQ1-1 alleviate aging-related intestinal barrier dysfunction via microbiota-short-chain fatty acid-AMPK/MLCK-tight junction axis.
Liu X, Guan K, Liu C, Sun Y, Ma Y, Mao K, Li Q, Wang R, Lu W
Journal of dairy science 2025 Dec;108(12):12949-12969
Journal of dairy science 2025 Dec;108(12):12949-12969
Intracellular interaction between FcRY receptor and IgY in ovarian vascular endothelial cells during avian maternal IgY transfer.
Okamoto M, Furukawa K, Mizushima S, Murai A
Poultry science 2025 Dec;104(12):105946
Poultry science 2025 Dec;104(12):105946
Genetic and functional analysis of ZMIZ1 in neurodevelopmental disorder with dysmorphic facies and distal skeletal anomalies (NEDDFSA): insights from muscle cells and signaling pathways.
Li S, Zhou D, Han Y, Feng C, Lv X, Fu G, Wei X, Wu C, Yu C, Yang Z
Pediatric research 2025 Dec 7;
Pediatric research 2025 Dec 7;
A CCL5(+)CD20(+)CD8(+) T cell subset drives pathogenic transformation of synoviocytes in rheumatoid arthritis via JAK-STAT signaling.
Jia H, Xue J, Jiang S, Li W, Wei X, Wang Y, Zhuang J, Zhu X, Li H, Liu X, Chu M, Zhang Z, Zhang J
Cell & bioscience 2025 Dec 6;16(1):2
Cell & bioscience 2025 Dec 6;16(1):2
Perfluorooctanoic acid and perfluorooctanesulfonic acid induce resistance to chemotherapy in colorectal cancer.
Liu J, Pang X, Li X, Huang N, Xu J, Wu Q, Yao R, Liu B, Lu H, Lian J
Journal of hazardous materials 2025 Dec 5;500:140583
Journal of hazardous materials 2025 Dec 5;500:140583
A shape complementarity strategy based on NCA029 enables potent HsClpP agonists for the treatment of small cell lung carcinoma.
Li L, Luo B, Wang X, Jian Z, Liu H, Ren B, Qiao W, Luo Y, Yang T
European journal of medicinal chemistry 2025 Dec 5;299:118008
European journal of medicinal chemistry 2025 Dec 5;299:118008
The NAWG combinatorial strategy activates MAPK signaling to restore extracellular matrix architecture in aging skin.
Zhang M, Pan L, Ren T, Du X, Mu Y, Liu S, Bao Y, Ma L, Luo J, Li F, Zheng F, Cao S, Yue H
Medicine 2025 Dec 5;104(49):e46335
Medicine 2025 Dec 5;104(49):e46335
Targeting FoxO1-STX17-mediated autophagic flux: Quercetin's therapeutic mechanism in diabetic nephropathy.
Hou B, Li Y, Tang J, Cao X, Zhang S, Cai Y, Guo J, Xi J, Wang D, Liu WJ, Lu H
European journal of pharmacology 2025 Dec 5;1008:178309
European journal of pharmacology 2025 Dec 5;1008:178309
SMARCA5 Cooperates With RSF1 to Promote Pathological Glycolysis and Chondrocyte Dysfunction in Osteoarthritis Through ATPase-Dependent Chromatin Regulation.
Xu J, Tang C, Shen H, Ni B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Dec 31;39(24):e71324
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Dec 31;39(24):e71324
Mild microwave hyperthermia promotes mitotic catastrophe, induces time-delayed cGAS-STING activation and restores sensitivity to anti-PDL1 therapy in Pan02 pancreatic cancer model.
Li N, He J, Chen M, Liang S, Zhang C, Pan W, Wang Q, Piao F, Wang R, Yu J, Gong G
Oncoimmunology 2025 Dec 31;14(1):2602216
Oncoimmunology 2025 Dec 31;14(1):2602216
Cigarette smoke-induced lung-brain barrier dysfunction drives neurocognitive impairment via inflammatory spill-over.
Yu X, Xiao H, Bao S, Dong Y, Dong Z, Zhao J, Wang G, Meng X, Wang F
Journal of neuroinflammation 2025 Dec 30;23(1):10
Journal of neuroinflammation 2025 Dec 30;23(1):10
TAT-PBX1 fusion protein alleviates LPS-induced acute lung injury via AMPK-TFAM signaling activation.
Chen Z, Liu X, Zuo K, Xin Y, Liu J
Molecular therapy : the journal of the American Society of Gene Therapy 2025 Dec 3;33(12):6537-6553
Molecular therapy : the journal of the American Society of Gene Therapy 2025 Dec 3;33(12):6537-6553
Mitochondrial protease ClpP deficiency protects against tubulointerstitial damage in diabetic kidney disease.
Wang H, Liu Y, Liu J, Zhang S, Li X, Sun L, Liu F, Liu Y, Xiao L
International immunopharmacology 2025 Dec 3;166:115641
International immunopharmacology 2025 Dec 3;166:115641
Neutrophil extracellular traps promote bone loss in type 1 diabetes via suppression of the FN1-PI3K/Akt signaling axis.
Liu X, Xiao D, Zhang D, Pan Y, Guo J, Zhang Y, Li S, Tang Q, Jin X, Sun T
International immunopharmacology 2025 Dec 3;166:115629
International immunopharmacology 2025 Dec 3;166:115629
Kaempferol inhibits atherosclerotic plaque development via dual-targeting of p53-p21-p16 senescence pathway and Nrf2/HO-1/NQO1 antioxidant mechanism: Insights from combined in vivo and in vitro research.
Cai X, Zhang Y, Zhu W, Gu N
International immunopharmacology 2025 Dec 3;166:115587
International immunopharmacology 2025 Dec 3;166:115587
Selenium improves behavioral performance in a rat model of autism spectrum disorder by mitigating oxidative stress and modulating the Sirt1/Keap1/Nrf2/HO-1 signaling pathway.
Shu Y, Yang J, Zhang P, Zhang X, Zhao X, Yan J, Zhang B, Du J
International immunopharmacology 2025 Dec 3;166:115556
International immunopharmacology 2025 Dec 3;166:115556
Targeting TDP1 phosphorylation by the natural product imperatorin promotes DNA repair and cardiac regeneration.
Fu W, Hou L, Yang X, Wang J, Jin J, Tong Q
Communications biology 2025 Dec 29;9(1):151
Communications biology 2025 Dec 29;9(1):151
Shikonin alleviates rotenone-induced Parkinson's disease neuroinflammation by targeting PKM2-mediated glycolytic MG-Hs production.
Zhao Y, Wang D, Mu D, Qu L, Li R
Cell communication and signaling : CCS 2025 Dec 29;23(1):537
Cell communication and signaling : CCS 2025 Dec 29;23(1):537
EXOSC3 knockdown induces G1/S phase arrest to suppress hepatocellular carcinoma cell proliferation.
Chen YM, Huo YX, Wei WS, Liu YX, Wang SH, Jiang L, Rong-He, Zhang HL, Jiang LH
Scientific reports 2025 Dec 29;15(1):44684
Scientific reports 2025 Dec 29;15(1):44684
Toxoplasma gondii-induced ferroptosis contributes to acute lung injury in mice.
Yuan X, Liu Z, Ma Y, Liu F, Bao P, Du B, Zhang X, Gong P, Zhang N, Li J, Li X, Wang X
Parasites & vectors 2025 Dec 28;19(1):55
Parasites & vectors 2025 Dec 28;19(1):55
ENO1-mediated deoxycytidine synthesis and gemcitabine resistance by stabilizing RRM2 in pancreatic cancer.
Li Y, Wang H, Chen L, Gong Y, Zheng D, Li F, Wu C, He Z, Yu C
Cell death & disease 2025 Dec 27;17(1):139
Cell death & disease 2025 Dec 27;17(1):139
Butin inhibits osteoarthritis progression by modulating the Nrf2/HO-1 signaling pathway and inhibiting NF-κB signaling.
Zhou P, Chang J, Wei X, Zhu C, Yang J, Wang C, Hu Y, Zhang C
Scientific reports 2025 Dec 26;15(1):45688
Scientific reports 2025 Dec 26;15(1):45688
Engineered vesicles enhance oral antibiotic absorption in proximal small intestine and mitigate gut dysbiosis.
Yu Y, Xu Y, Yu Z, Liu X, Guo J, Xiang M, Chen J, Widodo RT, Luo L
Nature communications 2025 Dec 25;17(1):1329
Nature communications 2025 Dec 25;17(1):1329
Elevated Flotillin-1 in Saliva and Salivary Glands: A Novel Non-Invasive Biomarker in an Alzheimer's Disease Mouse Model.
Kawakami S, Jung CG, Inoue R, Nakamura T, Sato S, Michikawa M
Diagnostics (Basel, Switzerland) 2025 Dec 24;16(1)
Diagnostics (Basel, Switzerland) 2025 Dec 24;16(1)
Cold Exposure Exacerbates Allergic Airway Inflammation via Ferroptosis: Evidence from a Murine Model.
Guo X, Wang C, Yu X, Zhang S, Zheng H, Liu T, Chen Z, Wang G, Wang F
Antioxidants (Basel, Switzerland) 2025 Dec 24;15(1)
Antioxidants (Basel, Switzerland) 2025 Dec 24;15(1)
Glutamine synthetase modulates YAP activation by stabilizing LATS under glutamine homeostasis.
Li S, Ling T, Wang Y, Shi J, Wang Q, Lv J, Li J, Liu Y, Zhang Y, Liu C, Xia T, Chen D, Wang W, Liu HX, Piao HL
Cell reports 2025 Dec 23;44(12):116620
Cell reports 2025 Dec 23;44(12):116620
GPX8 is transcriptionally regulated by KLF16 and promotes osteosarcoma progression.
Dong C, Gao Z, Li X
Journal of translational medicine 2025 Dec 2;23(1):1369
Journal of translational medicine 2025 Dec 2;23(1):1369
Honokiol attenuates diabetic nephropathy by targeting SIRT3 to suppress mitochondrial ROS-induced pyroptosis.
Yu K, Liu M, Zhang T, Guo C, Du L, Li M, Wang Q, Han N, Chi Y, Li Y
Diabetology & metabolic syndrome 2025 Dec 2;18(1):7
Diabetology & metabolic syndrome 2025 Dec 2;18(1):7
Single-cell transcriptomic analysis of the heterogeneity of mesenchymal and stromal cells and their regulon alteration during airway remodeling in asthma.
Chen X, Zhang H, Sun Z, Sun M, Wang J, Qiao G, Kang J, Liu K
Scientific reports 2025 Dec 2;15(1):42972
Scientific reports 2025 Dec 2;15(1):42972
Identifying CTSF and GSTM3 as chemoresistance therapeutic targets in breast cancer through multi-omics MR analysis.
Liu R, Yao Y, Lv Z, Huang J
iScience 2025 Dec 19;28(12):113908
iScience 2025 Dec 19;28(12):113908
Vitisin A inhibits liver fibrosis by promoting Nrf2/HO-1 pathway and inhibiting Cuproptosis.
Ding S, Hu D, Pan Y, Wang J, Wang L
Scientific reports 2025 Dec 19;15(1):44186
Scientific reports 2025 Dec 19;15(1):44186
Loss of the miR-221/222 Cluster Promotes the Pathogenesis of Osteoarthritis in Inflamed Mouse Chondrocytes and Osteoarthritis Models.
Liu X, Feng F, Jin Y, Ma C, Zhu Q, You Y, Gao M, Li X, Niu X, Wang J
Inflammation 2025 Dec 15;49(1):2
Inflammation 2025 Dec 15;49(1):2
Ginkgolide B Promotes Angiogenesis After Oxygen-Glucose Deprivation by Regulating AKT1 in bEnd.3 Cells.
Liao Y, Luo L, Ma Q, Yan S, He M, Liu L, Gao X, Zhou D, Chen Y
Frontiers in bioscience (Landmark edition) 2025 Dec 15;30(12):46724
Frontiers in bioscience (Landmark edition) 2025 Dec 15;30(12):46724
Semi-inductive dataset construction and framework optimization for practical drug target interaction prediction with ScopeDTI.
Chen Y, Ji X, Zhang Z, Zhu Z, Zhou Y, Su C, Lin YC, Huang HY, Wei K, Lai Y, Chen K, Lin X, Zhang Y, Fu J, Huang Y, Cui S, Yen SC, Zhang T, Warshel A, Huang HD
Nature communications 2025 Dec 13;16(1):11509
Nature communications 2025 Dec 13;16(1):11509
Deoxycholic acid derived from the gut microbiota involved in the regulation of adaptive thermogenesis in response to dietary protein restriction in plateau pika.
Shi F, Yang Z, Zhang L, Zou D, Yu J, Guo N, Ren S, Tang X, Gu C, Xu R, Ru Y, Zhang Y, Wang D
Microbiome 2025 Dec 12;14(1):29
Microbiome 2025 Dec 12;14(1):29
Haematococcus pluvialis ameliorates renal fibrosis by restoring mitophagy via PINK1-Parkin-p62-LC3 signaling.
Wu Y, Chen C, Xie J, Chang X, Zhang Y, Zheng Y, Yuan Y, Hu W, Xie X
NPJ science of food 2025 Dec 11;10(1):9
NPJ science of food 2025 Dec 11;10(1):9
Targeting polyamine metabolism induces oxidative/carbonyl stress to reinvigorate antitumor immunity in prostate cancer.
Zhang A, Zheng J, Xu Y, Fu S, Du Q, Zhao C, Meng Y, Li M, Wang L, Wang S, Shi T, Yang C, Jiang P, Wang Y, Zhao Z, Zhang Z, Zhao S, Qin X, Geng H, Yu N
Journal of controlled release : official journal of the Controlled Release Society 2025 Dec 10;388(Pt 1):114283
Journal of controlled release : official journal of the Controlled Release Society 2025 Dec 10;388(Pt 1):114283
Fennel essential oil and its nanoemulsion modulate macrophage-mediated inflammatory responses and promote pressure ulcer healing.
Luo Z, Zeng L, Zhao Z, Zheng Y, Wan D
International immunopharmacology 2025 Dec 10;167:115631
International immunopharmacology 2025 Dec 10;167:115631
Effect of Limosilactobacillus reuteri SBC5-3 Cell-free Supernatant on Growth Performance, Intestinal Inflammation, and Microbiota in Weaned Piglets Challenged With Enterotoxigenic Escherichia coli K88.
Xu L, Bao G, Chen S, Liu C, Zi X, Hu M, Liu Q, Lin Q, Cao Z
Probiotics and antimicrobial proteins 2025 Dec 10;
Probiotics and antimicrobial proteins 2025 Dec 10;
The 3D Genome Structure of a Blcap-Linked Silencer Loop Regulates Terminal Differentiation During Lens Fiber Cell Denucleation.
Ke S, Liu Z, Ma J, Zheng Y, Luo L
Investigative ophthalmology & visual science 2025 Dec 1;66(15):26
Investigative ophthalmology & visual science 2025 Dec 1;66(15):26
Allele-Specific Methylation Links Non-coding Variant of rs2280906 to MYOM2 Regulation in Schizophrenia.
Li Q, Gai Y, Li Z, Wang Z, Li X, Wu W, Zhao C
Molecular neurobiology 2025 Dec 1;63(1):230
Molecular neurobiology 2025 Dec 1;63(1):230
FERMT1 suppresses the ferroptosis of glioma cells by interacting with MBOAT2.
Pan Z, Ke C, Zhang B, Lin Q, Zheng H, Zheng S, Huang J, Hu W
Experimental cell research 2025 Dec 1;453(2):114794
Experimental cell research 2025 Dec 1;453(2):114794
MicroRNA-29b-3p promotes endothelial cell inflammation via NTRK2/PI3K/NLRP3 pathway in Moyamoya disease.
Wei L, Ren H, Lin Y, Deng X, Liu Y, Zeng J, Lin J, Gao X, Sun J, Huang Y
European journal of medical research 2025 Dec 1;31(1):10
European journal of medical research 2025 Dec 1;31(1):10
HIC2 suppresses glioblastoma progression via transcriptional repression of SEMA3A and inhibition of TGF-β signaling.
Zhang L, Yang J, Ke X, Huang N, Zhou D, Cai H
Free radical biology & medicine 2025 Dec 1;240:674-684
Free radical biology & medicine 2025 Dec 1;240:674-684
Epimedin B attenuates ovariectomy-induced bone loss by suppressing osteoclastogenesis through decreasing ROS production and targeting ESR1.
Lai Y, Li H, Zhou T, Chen H, Yang J, Mo G, Li Y, Li Q, Deng X, Fan S, Gu P
Free radical biology & medicine 2025 Dec 1;240:347-363
Free radical biology & medicine 2025 Dec 1;240:347-363
Inhibition of ALOX5-dependent ferroptosis by 6-C-methylquercetin: a potential therapeutic approach for alleviating rheumatoid arthritis.
Jia B, Zhou S, Liu M, Zhang M, Jiang X, Guo X, Bi Y
Free radical biology & medicine 2025 Dec 1;240:153-169
Free radical biology & medicine 2025 Dec 1;240:153-169
Ezh2 Regulates Early Astrocyte Morphogenesis and Influences the Coverage of Astrocytic Endfeet on the Vasculature.
Zhao X, Zhang M, Zou W, Li C, Zhang S, Lv Y, Su L, Ji F, Jiao J, Gao Y
Cell proliferation 2025 Aug;58(8):e70015
Cell proliferation 2025 Aug;58(8):e70015
Stroke-Homing Peptide-DNase1 Alleviates Intestinal Ischemia Reperfusion Injury by Selectively Degrading Neutrophil Extracellular Traps.
Liu T, Lv X, Xu Q, Qi X, Qiu S, Luan Y, Shen N, Cheng J, Jin L, Tian T, Liu W, Jin L, Jia Z
Cell proliferation 2025 Aug;58(8):e70010
Cell proliferation 2025 Aug;58(8):e70010
Ferroptosis promotes 5-aminolevulinate acid-based photodynamic therapy in cervical cancer.
Liu Q, Han Q, Shi J, Wu Z, Ma L, Li Y, He H, Guo H
Photodiagnosis and photodynamic therapy 2025 Aug;54:104726
Photodiagnosis and photodynamic therapy 2025 Aug;54:104726
Sequential simulation of regeneration-specific microenvironments using scaffolds loaded with nanoplatelet vesicles enhances bone regeneration.
Li W, Shen Q, Tong T, Tian H, Lian X, Wang H, Yang K, Dai Z, Li Y, Chen X, Wang Q, Yang D, Wang F, Hao F, Wang L
Bioactive materials 2025 Aug;50:475-493
Bioactive materials 2025 Aug;50:475-493
ASPM Induces Radiotherapy Resistance by Disrupting Microtubule Stability Leading to Chromosome Malsegregation in Non-Small Cell Lung Cancer.
Zhong T, Liu N, Wang J, Xie S, Liu L, Wang M, Wu F, Chen X, Xiao C, Gongye X, Wu M, Wen L, Yu J, Chen D
Exploration (Beijing, China) 2025 Aug;5(4):e20230024
Exploration (Beijing, China) 2025 Aug;5(4):e20230024
Berberine Enhances the Sensitivity of Colorectal Cancer Cells to 5-FU Through Smoothing Endoplasmic Reticulum Stress-Mediated Autophagic Flux.
Xu J, Hu M, Li Y, Gong H, Zhang X, He Z, Xiao C, Yang C, Zeng J
Cell biology international 2025 Aug;49(8):1042-1055
Cell biology international 2025 Aug;49(8):1042-1055
Andrographolide Attenuates Myocardial Ischemia-Reperfusion Injury in Mice by Up-Regulating PPAR-α.
Zhang S, Ye Y, Li Q, Zhao J, Song R, Huang C, Lu X, Huang C, Yin L, You Q
Inflammation 2025 Aug;48(4):2341-2354
Inflammation 2025 Aug;48(4):2341-2354
Inhibition of GDNF-Driven Macrophage-to-Myofibroblast Transition Protects Against Colitis-Associated Intestinal Fibrosis.
Zeng J, Du XL, Lu QQ, Chen WQ, Yang XJ
Inflammation 2025 Aug;48(4):2069-2077
Inflammation 2025 Aug;48(4):2069-2077
Quorum Sensing Molecule Autoinducer-2 Promotes Macrophage Classical Polarization and Exacerbates Periodontal Inflammation Via Nf-Κb Signalling.
Zhou H, Huang J, Fan Z, Sun W, Xu Y, Li L
Inflammation 2025 Aug;48(4):1974-1986
Inflammation 2025 Aug;48(4):1974-1986
Inhibition of FKBP5 Alleviates Inflammation and Intestinal Barrier Dysfunction in Sepsis.
Li J, Apizi A, Song T, Kamilijiang P, Yu X, Chai R, Yu Z
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2025 Aug;45(8):290-299
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2025 Aug;45(8):290-299
Combining network pharmacology and RNA sequencing to reveal the mechanism of emodin for the treatment of human neuroblastoma.
Jiang HM, Huang SY, Huang D, Zhao Y, Yuan Y, Huang HF, Tang Y, Zhang JF
Naunyn-Schmiedeberg's archives of pharmacology 2025 Aug;398(8):10093-10109
Naunyn-Schmiedeberg's archives of pharmacology 2025 Aug;398(8):10093-10109
Protection of Dipsacoside B Against Cerebral Ischemia/Reperfusion Injury via Activating PINK1/Parkin-Mediated Mitophagy.
Sun G, Chang C, Guo C
Journal of biochemical and molecular toxicology 2025 Aug;39(8):e70416
Journal of biochemical and molecular toxicology 2025 Aug;39(8):e70416
A multifunctional hydrogel system with synergistic effects against Staphylococcus aureus infections and inflammation in perioperative cataract surgery.
Zheng W, Lin M, Cheng H, Gao X, Xiang Y, Wan W, Zheng S, Huang X, Hu K
Materials today. Bio 2025 Aug;33:102080
Materials today. Bio 2025 Aug;33:102080
BMSCs-targeting piezoelectric stimulation and immunomodulatory dual-functional hydrogel for promoting diabetic bone regeneration.
Dong J, Dong W, Ran H, Wu D, Wang X, Chen H, Cao J, Wang X, Lin X, Lei W, Wang T, Feng Y
Materials today. Bio 2025 Aug;33:102015
Materials today. Bio 2025 Aug;33:102015
Dissolvable microneedle-assisted transdermal administration of diacerein nanoparticles achieved satisfactory therapeutic effects in tendon-bone insertion repair by reducing oxidative stress and inflammation.
Sun J, Chen QZ, Hong AZ, Ju F, Wang HL, Zhang B, Liu W, Sun YC, Tan J, Yang QQ, Zhou YL
Materials today. Bio 2025 Aug;33:101999
Materials today. Bio 2025 Aug;33:101999
Homeobox C6 is Up-Regulated and Affects the Pathogenesis of Endometriosis.
Jiang J, Zhang L, Li L
Reproductive sciences (Thousand Oaks, Calif.) 2025 Aug;32(8):2574-2582
Reproductive sciences (Thousand Oaks, Calif.) 2025 Aug;32(8):2574-2582
Zika virus capsid protein impairs neural differentiation.
Wang Y, Ma ZH, Hassaan NA, Hao G, Wang PH, Yao M, Wu C, Chen M, Xing L
International journal of biological macromolecules 2025 Aug;319(Pt 2):145479
International journal of biological macromolecules 2025 Aug;319(Pt 2):145479
A Decoy Oligodeoxynucleotides Disturbing Forkhead Box O3 Mediated ctnna2 Transcriptional Repression Prevents Postoperative Neurocognitive Disorder in Mice.
Wu Z, Xie D, Zhao J, Zhao J, Liu H, Xing D, Gu T, Guo Y, Wang D, Lu Z, Dong H, Zhao J, Deng J
CNS neuroscience & therapeutics 2025 Aug;31(8):e70454
CNS neuroscience & therapeutics 2025 Aug;31(8):e70454
Multifunctional targeted nanosystem based on aggregation-induced emission: Enhanced synergistic mild-photothermal chemotherapy of prostate cancer via downregulation of heat shock protein 70 under NIR-II imaging.
Gui B, Jiang N, Pu H, Zhong F, Huang X, Wang Z, Liu Q, Wang H, Zhou Y, Zhou Q, Deng Q
Colloids and surfaces. B, Biointerfaces 2025 Aug;252:114667
Colloids and surfaces. B, Biointerfaces 2025 Aug;252:114667
Schwann cells transplantation improves nerve injury and alleviates neuropathic pain in rats.
Zhang WJ, Li X, Liao JX, Hu DX, Huang S
Purinergic signalling 2025 Aug;21(4):611-619
Purinergic signalling 2025 Aug;21(4):611-619
A tumor microenvironment-responsive nanocomposite for enhanced copper retention and hypoxia reversal to promote cuproptosis in tumor treatment.
Chen W, Lin C, Gao Z, Huang Y, Wang X, Zhang Q, Zhang Y, Tan M, Hou Z
Acta biomaterialia 2025 Aug;202:463-475
Acta biomaterialia 2025 Aug;202:463-475
Hypoxia-induced phenotypic transformation of scleral fibroblasts promotes activation of the adhesion patch pathway through paracrine effects leading to choroidal damage.
Li Y, Zhang O, Pan Y, Du X, Li J
Biochimica et biophysica acta. Molecular cell research 2025 Aug;1872(6):119992
Biochimica et biophysica acta. Molecular cell research 2025 Aug;1872(6):119992
Proprotein convertase subtilisin/kexin type 9 contributes to cisplatin-induced acute kidney injury by interacting with cyclase-associated protein 1 to promote megalin lysosomal degradation.
Wang Z, Yu X, Ma H, Yao S, Li Z, Zhang R, Liang H, Jiao J
Biochimica et biophysica acta. Molecular cell research 2025 Aug;1872(6):119984
Biochimica et biophysica acta. Molecular cell research 2025 Aug;1872(6):119984
Protective effect of micheliolide against inflammation and oxidative stress in asthma through the MAPK/NF-κB signalling pathway.
Wang J, Han D, Han L, Zhang Q, Liu S, Hu J, Shang Y
The World Allergy Organization journal 2025 Aug;18(8):101091
The World Allergy Organization journal 2025 Aug;18(8):101091
Cold exposure promotes the progression of osteoarthritis through downregulating APOE in cartilage.
Zhang Y, Fu M, Zhou C, Wang X, Jiang Z, Jiang C, Guo S, Pang Z, Wang C, Yu T, An S, Wang X, Wang Z
EMBO molecular medicine 2025 Aug;17(8):2137-2162
EMBO molecular medicine 2025 Aug;17(8):2137-2162
Single cell RNA-sequencing reveals BHLHE40 and NDRG1 as key regulatory molecules modulating the trophoblastic senescence in preeclampsia.
Zhang Y, Chu J, Yu Z, Gong Y
Placenta 2025 Aug;168:74-87
Placenta 2025 Aug;168:74-87
Short-Chain Fatty Acids Promote Follicular Development by Alleviating Oxidative Stress-Induced Granulosa Cells Apoptosis in Sows.
Qin W, Xu B, Lei X, Yan X
The Journal of nutrition 2025 Aug;155(8):2611-2621
The Journal of nutrition 2025 Aug;155(8):2611-2621
Curcumin Promotes the Recovery of Motor Function After Brachial Plexus Avulsion Injury in Rats.
Li S, He B, Zhou G, Wu L, Wen X, Deng L, Lin S, Liu G, Chen S, Xiao Z
Brain and behavior 2025 Aug;15(8):e70728
Brain and behavior 2025 Aug;15(8):e70728
Rapid discovery of drug-introduced multiple organ dysfunction via NIR-II fluorescent imaging.
Jiang P, Song R, Hu Y, He X, Zhang Z, Wei X, Wang Z, Guo DA, Chen H
Acta pharmaceutica Sinica. B 2025 Aug;15(8):4285-4299
Acta pharmaceutica Sinica. B 2025 Aug;15(8):4285-4299
Suppressing neuroinflammation by Shenfu injection against ischemic stroke in mice via inhibiting RAGE-PI3K-Akt pathway.
Li S, Wang Y, Sun X, Lu L, Yong Y, Kong X, Song J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Aug;144:156940
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Aug;144:156940
Naringenin Accelerates Diabetic Wound Healing via Regulating Macrophage M2 Polarization and Efferocytosis.
Wang B, Huang Y, Ding Y, Chen J, Chen Y, Zhang H, Tan Q
Food science & nutrition 2025 Aug;13(8):e70688
Food science & nutrition 2025 Aug;13(8):e70688
The mechanism by which MALAT1/CREG1 regulates premature rupture of fetal membrane through autophagy mediated differentiation of amniotic fibroblasts.
Huang X, Huang T, Chen A, Shao Y
Non-coding RNA research 2025 Aug;13:29-42
Non-coding RNA research 2025 Aug;13:29-42
Multiple omics-based machine learning reveals specific macrophage sub-clusters in renal ischemia-reperfusion injury and constructs predictive models for transplant outcomes.
Wu J, Zhang F, Li Z, Gan L, Cao H, Cao H, Hao C, Sun Z, Wang W
Computational biology and chemistry 2025 Aug;117:108421
Computational biology and chemistry 2025 Aug;117:108421
Newcastle disease virus induces degradation of folliculin to regulate host cell energy metabolism and facilitate viral replication.
Yang M, Kan X, Li X, Sun Y, Liao Y, Qiu X, Tan L, Song C, Ding C
Poultry science 2025 Aug;104(8):105314
Poultry science 2025 Aug;104(8):105314
Macrophagic Ym1 orchestrates γδT cell-derived IL-17 production and keratinocyte functionality to mediate psoriasis-like skin inflammation.
Zhang W, Li F, Wang Y, Fan M, Zhao Y, Guan Y, Zhou Y, Lu S, Holmdahl R, Meng L, Zhu W
Communications biology 2025 Aug 8;8(1):1186
Communications biology 2025 Aug 8;8(1):1186
SD49-7 attenuates cardiac hypertrophy by upregulation of S100B through KDM4A inhibition.
Zhang Z, Gao M, Yan T, Feng Z, Lu S, Tang L, Li X, Wang W, Yang P, Zhou S, Hu Y, Duan Y, Zhang S
Biochemical pharmacology 2025 Aug 8;242(Pt 1):117218
Biochemical pharmacology 2025 Aug 8;242(Pt 1):117218
ZC3H13 mediates N6-methyladenosine modification of SNTB1 to promote epithelial-mesenchymal transition in gastric cancer.
Xie X, Zhao Y, Liu J, Li H, Zhu X, Liu Y, Sang Y, Xu K, Du F, Ren H, Cui X, Cai B, Chen H, Wu N, Hou G, Jing C, Chong W, Li L, Shang L
Cell death & disease 2025 Aug 7;16(1):596
Cell death & disease 2025 Aug 7;16(1):596
Camellia japonica Flower Extract and the Active Constituent Hyperoside Repair DNA Damage Through FUNDC1-Mediated Mitophagy Pathway for Skin Anti-Aging.
Gao H, Shi J, Li G, Lai Z, Liu Y, Yuan C, Mei W
Antioxidants (Basel, Switzerland) 2025 Aug 6;14(8)
Antioxidants (Basel, Switzerland) 2025 Aug 6;14(8)
Integrating network pharmacology and experimental validation to explore the mechanism of Yiqi Ziyin in treating immune thrombocytopenia.
Wang J, Wang B, Zhang Y, Wu LQ
Scientific reports 2025 Aug 5;15(1):28640
Scientific reports 2025 Aug 5;15(1):28640
Inhibition of UCH-L1 enhances immunotherapy efficacy in triple-negative breast cancer by stabilizing PD-L1.
He L, He J, Jiang T, Gong R, Wan X, Duan M, Chen Z, Cheng Y
European journal of pharmacology 2025 Aug 5;1000:177743
European journal of pharmacology 2025 Aug 5;1000:177743
Garlic-Derived Allicin Attenuates Parkinson's Disease via PKA/p-CREB/BDNF/DAT Pathway Activation and Apoptotic Inhibition.
Zeng W, Wang Y, Liu Y, Liu X, Qi Z
Molecules (Basel, Switzerland) 2025 Aug 4;30(15)
Molecules (Basel, Switzerland) 2025 Aug 4;30(15)
RPN1 Is Associated With Immunosuppression in Pan-Cancer and Affects the Malignant Phenotype of Tumor.
Lin S, Wu C, Liu Q, Luo F, Tan J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 31;39(16):e70978
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 31;39(16):e70978
Inflammation Inhibits HECTD1-Mediated AURKA Ubiquitination to Cause Extracellular Matrix Degradation in Osteoarthritis via Enhancing Cap-Dependent mRNA Translation of ADAMTS12.
Xia D, Yu C, Zhou XP, Huang L, Yang S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 31;39(16):e70953
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 31;39(16):e70953
USP44 Regulates Chemoresistance Induced by ROS and the MAPK/NF-κB Pathway Through the Stabilization of ITGB4 in Gastric Cancer.
Xiao W, Lou Y, Wu P, Yang P, Wu H, Song J, Liu L, Xu C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 31;39(16):e70945
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 31;39(16):e70945
Galnt4 Knockdown Modulates Lysosomal Function to Reduce Foam Cell Formation and Attenuate Atherosclerotic Plaque Progression.
Teng D, Jia W, Che H, Chen H, He X, Gong L, Dong H, Song J, Pan Y, Wang H, Yang J, Zhong L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 31;39(16):e70931
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 31;39(16):e70931
METTL11A serves as a novel therapeutic target for acute myeloid leukemia through regulation of the p38-MAPK pathway.
Li J, Zhang J, Zhang P
Translational cancer research 2025 Aug 31;14(8):4561-4573
Translational cancer research 2025 Aug 31;14(8):4561-4573
PPARα deletion induces depressive-like behaviors by impairing neuronal synaptic plasticity and transmission.
Zhuo R, Cheng X, Yang L, Wang C, Yang L, Zhang Y, Zeng Y, Li Y
Neuroscience 2025 Aug 30;582:82-93
Neuroscience 2025 Aug 30;582:82-93
Non-SMC condensin I complex subunit H promotes cell proliferation and inhibits cell apoptosis of clear cell renal cell carcinoma by activating the PI3K/AKT pathway.
Ha H, Wang J, Zhang X, Du Y, Xiong W, Li S, Shang P
Translational andrology and urology 2025 Aug 30;14(8):2153-2170
Translational andrology and urology 2025 Aug 30;14(8):2153-2170
Production of Fc-fused receptor agonists for glucagon-like peptide-1/glucose-dependent insulinotropic polypeptide (GLP-1/GIP) in the milk of transgenic mice.
Rao Y, Yu S, Wang BZ, Cui S, Gou KM
Transgenic research 2025 Aug 3;34(1):38
Transgenic research 2025 Aug 3;34(1):38
Shaoyao Gancao decoction promotes splenic immune homeostasis mediating cGAS-STING signaling pathway to delay autoimmune hepatitis progression.
Xu A, Zhang Z, Zhu B, Xiao M, Jiang X, Yang Y, Zhao M
Journal of ethnopharmacology 2025 Aug 29;352:120121
Journal of ethnopharmacology 2025 Aug 29;352:120121
Qingxie Fuzheng granules attenuate cancer cachexia by restoring gut microbiota homeostasis and suppressing IL-6/NF-κB signaling in colorectal adenocarcinoma.
Jin Y, Lu L, Hua H, Chen B, Fang W, Lin K, Ren P, Geng Z, Wang L, Yan X, Chen W, Lin J
Hereditas 2025 Aug 29;162(1):178
Hereditas 2025 Aug 29;162(1):178
Exosomes derived from umbilical cord mesenchymal stem cells alleviate jaw bone marrow mesenchymal stem cells senescence and restore osteogenic differentiation potential.
Li H, Xu N, Li S, Wang X, Li A, Wang H, Wu S, Zhou S, Cai C, Zhang T
Stem cell research & therapy 2025 Aug 29;16(1):475
Stem cell research & therapy 2025 Aug 29;16(1):475
5-HT(2a)R contributes to pulmonary arterial hypertension by modulating the AHR pathway.
Lu X, Hu H, Liu Y, Guo Z, Song W, Li W, Deng B, Sun L, Dong X, Zhang H, Wang S, Jiang X, Zhai Z, Hu Y, Zhang H, Fan P, Yang P
Biochemical pharmacology 2025 Aug 28;242(Pt 1):117285
Biochemical pharmacology 2025 Aug 28;242(Pt 1):117285
Effect of the DPP4 Inhibitor Sitagliptin on Ferroptosis in Epilepsy.
Hou B, Li L, Wang F, Guo J
Journal of integrative neuroscience 2025 Aug 28;24(8):39469
Journal of integrative neuroscience 2025 Aug 28;24(8):39469
MS4A6A/Ms4a6d deficiency disrupts neuroprotective microglia functions and promotes inflammation in Alzheimer's disease model.
Jiao HS, Ge YJ, Huang LY, Liu Y, Wu BS, Lian PP, Hao YN, Han SS, Li YT, Wu KM, Wu CY, Cheng TL, Yuan P, Yu JT
Molecular neurodegeneration 2025 Aug 28;20(1):94
Molecular neurodegeneration 2025 Aug 28;20(1):94
Bleomycin promotes cellular senescence and activation of the cGAS-STING pathway without direct effect on fibrosis in an idiopathic pulmonary fibrosis model.
Miura Y, Milad N, Takata A, Kanazawa S
Aging 2025 Aug 28;17(8):2189-2211
Aging 2025 Aug 28;17(8):2189-2211
A novel SOX6 + melanoma cell subtype promotes early microsatellite invasion in Asian acral melanoma through fatty acid transport disorder.
Lv C, Chen K, Wang T, Jiang J, Hu G, Gu J, Liu T, Wang S, Dai H, Wang Y
Journal of experimental & clinical cancer research : CR 2025 Aug 27;44(1):254
Journal of experimental & clinical cancer research : CR 2025 Aug 27;44(1):254
The study of JAZF1-mediated apoptosis of decidual stromal cells by activating the NF-κB signaling pathway in spontaneous preterm birth.
Gong MQ, Hu YY, Zhang YQ, Wang XD
BMC pregnancy and childbirth 2025 Aug 27;25(1):891
BMC pregnancy and childbirth 2025 Aug 27;25(1):891
CircCRIM1 promotes the translation of HIF-1α protein through its interaction with PTBP3 and enhances malignant progression and angiogenesis in glioblastoma.
Liu Y, Luo Y, Song D, Meng W, Bai J, Li Y, Lin X, Wang J, Fan D, Gu Y
Biochemical pharmacology 2025 Aug 27;242(Pt 1):117279
Biochemical pharmacology 2025 Aug 27;242(Pt 1):117279
Hybrid-Ligand Metal-Organic Frameworks Enabling Radio-Radiodynamic-Chemodynamic Therapy Primes Checkpoint Blockade Immunotherapy in Hypoxic Tumors.
Zhai S, You Z, Li J, Zheng B, Zhao X, Jiang W, Su D, Wang H, Han C, Lu K
ACS nano 2025 Aug 26;19(33):30100-30114
ACS nano 2025 Aug 26;19(33):30100-30114
L-arginine synergistic with 5-fluorouracil intervenes in DNA damage repair via the DNA-PKcs/ATM/ATR pathway in hepatocellular carcinoma cells.
Wang H, Xie H, Lin Y, Zhang Z, Zhang M, Zhao J, Zhao Q, Liu L
Acta biochimica et biophysica Sinica 2025 Aug 22;58(3):621-637
Acta biochimica et biophysica Sinica 2025 Aug 22;58(3):621-637
Advanced glycation end products induce inflammaging in periodontal ligament fibroblasts through RAGE/AKT/mTOR/glycolysis pathway.
Xiong L, Shu J, Gao H, Qin Y, Zhang Y, Chang X, Dong Q, Chen H
Acta odontologica Scandinavica 2025 Aug 21;84:479-490
Acta odontologica Scandinavica 2025 Aug 21;84:479-490
LncRNA938/ TAF9/TTK axis promotes EMT and serves as a therapeutic target in hepatoblastoma.
Jin C, Dong B, Xie Y, Chen X, Wu S, Du F, Dong Q, Zhu C
Journal of translational medicine 2025 Aug 21;23(1):946
Journal of translational medicine 2025 Aug 21;23(1):946
Targeting TSPAN1 promotes ferroptosis in endometrial cancer cells, reduces energy metabolism and inhibits malignant behavior.
Fan Y, Xiao H, Wu Y, Yan R, Li P, Ma H
Gene 2025 Aug 20;962:149553
Gene 2025 Aug 20;962:149553
Erianin induces GSDMD-dependent pyroptosis and synergistically enhances doxorubicin efficacy via the PI3K/AKT signaling pathway in diffuse large B-cell lymphoma.
Mei H, Qiu M, Liu R, Song T, Gao Z, Zhang Q, Wang Y, Hao J, Gao M, Yang Z, Wang H
Chinese medical journal 2025 Aug 20;
Chinese medical journal 2025 Aug 20;
Gut-resident Phascolarctobacterium succinatutens decreases fat accumulation via MYC-driven epigenetic regulation of arginine biosynthesis.
Lan Q, Liufu S, Chen B, Wang K, Chen W, Xiao L, Liu X, Yi L, Liu J, Xu X, Liu C, Liu M, Yin Y, Ma H
NPJ biofilms and microbiomes 2025 Aug 2;11(1):150
NPJ biofilms and microbiomes 2025 Aug 2;11(1):150
Structure-based drug design of small molecule AKT1 inhibitors to treat glioma.
Jia X, Han Q, Ma X, Sun Z
Journal of computer-aided molecular design 2025 Aug 19;39(1):69
Journal of computer-aided molecular design 2025 Aug 19;39(1):69
CX26 promotes pancreatic cancer progression by competitively inhibiting interaction of c-Myc with PSMD2 and enhancing c-Myc stability.
He C, Tang C, Guo J, Yin X, Zhu Q, Fang C
Journal of translational medicine 2025 Aug 19;23(1):939
Journal of translational medicine 2025 Aug 19;23(1):939
Targeting ATF4-DDIT4/TXNIP induced mitochondrial dysfunction and ferroptosis: ISRIB as novel therapy for septic cardiomyopathy.
Chen Y, Feng X, Li Z, Wang X, Xiong W, Liu J, Wang G, Xu W, Jin R, Zhang L, Qian Z
Journal of translational medicine 2025 Aug 19;23(1):938
Journal of translational medicine 2025 Aug 19;23(1):938
HIIT and MICT mitigate endothelial dysfunction in early atherosclerotic mice via PCSK9 inhibition.
Liu G, Zhao B, Chen Q, Li X, Zhu X, Duan M, Zhang M, Liu Z, Wen X, Guo J, Zheng M, Wang R, Luo M
Scientific reports 2025 Aug 19;15(1):30411
Scientific reports 2025 Aug 19;15(1):30411
WDR26-related Skraban-Deardorff syndrome: clinical, genetic and pathomechanistic insights.
Lin X, Chen H, Zhou Y, Peng P, Lei B, Zhou S, Zhu S, Stauber T, He H, Peng J
European journal of medical research 2025 Aug 18;30(1):757
European journal of medical research 2025 Aug 18;30(1):757
Targeting HMGCS2: Ketogenesis Suppression Accelerates NAFLD Progression in T2DM Comorbidity, While Cynaroside Ameliorates NASH in Concomitant T2DM.
Shu Y, Shen W, Feng W, Pan M, Xu X, Zheng S, Jin H
Biomolecules 2025 Aug 18;15(8)
Biomolecules 2025 Aug 18;15(8)
NDUFB9 ameliorates CUMS-induced depression-like behavior by promoting mitophagy.
Sun Y, Li L, Yang X, Yin S, Xiao Z
Translational psychiatry 2025 Aug 18;15(1):292
Translational psychiatry 2025 Aug 18;15(1):292
Comparisons of miRNA profiles of exosomes derived from human iPSCs, ADSCs, and BMSCs and effects on chondrocyte function.
Chang LH, Chuang SC, Wu SC, Fu YC, Chen JW, Wu CW, Lin YS, Liu CY, Chung YH, Chang JK, Chen CH, Ho ML
Bone & joint research 2025 Aug 18;14(8):696-712
Bone & joint research 2025 Aug 18;14(8):696-712
Selenoprotein K-dependent MyD88 palmitoylation promotes hepatic metaflammation in high-fat diet fed mice.
You M, Zhang Y, Gao M, Zhao W, Wei L, Ruan XZ, Chen Y
Free radical biology & medicine 2025 Aug 16;236:144-159
Free radical biology & medicine 2025 Aug 16;236:144-159
A novel prognostic risk score associated with resistance to docetaxel chemotherapy for predicting biochemical recurrence-free survival in patients with prostate cancer.
Zhu D, Zhu H, Huang T, Fan W
Discover oncology 2025 Aug 16;16(1):1565
Discover oncology 2025 Aug 16;16(1):1565
Proteomics profiling reveals the potential targets of Apatinib inhibiting the proliferation of glioma U251 cell.
Zhang Y, Li Y, Xu F, Pan L, Zhang S, Zhang P, Qin X, Yang Z, Yang W, Zhang W, Kong D
Biochemical and biophysical research communications 2025 Aug 15;775:152148
Biochemical and biophysical research communications 2025 Aug 15;775:152148
Succinate accumulation induces pyroptosis and mitochondrial damage via the inhibition of ATP5F1D in HUVECs.
Huang H, Cui J, Tang D, Xiang X, Mao J, He Z, Hu H, He Z, He L, Tang H
Acta biochimica et biophysica Sinica 2025 Aug 15;57(12):2011-21
Acta biochimica et biophysica Sinica 2025 Aug 15;57(12):2011-21
RIPK3-MLKL dependent necroptosis mediates depressive-like behavior by facilitating neuroinflammation.
Zheng H, Xu ZY, Hu T, Wu YL, Huang CW, Li JM, Cao ZY, Wang W, Jiang CL, Su WJ
Journal of neuroimmunology 2025 Aug 15;405:578643
Journal of neuroimmunology 2025 Aug 15;405:578643
Oroxin A suppresses colorectal tumor growth by regulating the TRIM24-mediated ferroptosis and TSPO pathway.
He C, Weng C, Lai Z, Luo H, Chen K, Li T, Li W, Li G
iScience 2025 Aug 15;28(8):113196
iScience 2025 Aug 15;28(8):113196
Cancer cell SPOCD1 promotes colorectal cancer liver metastasis by activating the CXCL12/CXCR4 signaling pathway in cancer-associated fibroblasts.
Peng G, Zhong L, Luo L, Ju Y, Lu Y, Ng L, Foo DC, Cheng F, Huang L, Ouyang M
Journal of translational medicine 2025 Aug 13;23(1):902
Journal of translational medicine 2025 Aug 13;23(1):902
Indoleamine 2,3-dioxygenase can improve ovarian function in premature ovarian insufficiency via aromatic hydrocarbon receptor and regulatory T cells†.
Hu A, Mu Y, Huang G, Wang Z, Zhao S, Xu W, Chen P, Guo X
Biology of reproduction 2025 Aug 13;113(2):331-344
Biology of reproduction 2025 Aug 13;113(2):331-344
NAT10 Mediates Cardiac Fibrosis Induced by Myocardial Infarction Through ac4C Modification of TGFBR1 mRNA.
Zhou J, Chen Y, Chen J, Xia G, Zeng J, Wang L
Cell biology and toxicology 2025 Aug 12;41(1):125
Cell biology and toxicology 2025 Aug 12;41(1):125
Cathepsin D promotes acute myeloid leukemia progression through stabilization of the anti-apoptotic proteins.
Jiang H, Wang Y, Wang C, Yang L, Wang S, Wang F, Xue S, Zhang Z, Fu H, Dong T, Yuan J, Li Z, Li K
Cell death & disease 2025 Aug 12;16(1):611
Cell death & disease 2025 Aug 12;16(1):611
miRNA-204-5p acts as a tumor suppressor in gastric cancer by inhibiting cell migration, invasion, and glycolysis via the RAB22A/PI3K/AKT axis.
Pan W, Tan Y, Chen X, Zeng L, Lv Y, Yang J
Scientific reports 2025 Aug 12;15(1):29536
Scientific reports 2025 Aug 12;15(1):29536
Ergosterol from edible fungi: Enhancing fatty acid oxidation via CPT1A to protect against diabetic kidney disease.
Dong Z, Li X, Wang X, Xu J, Xu W
Food & function 2025 Aug 11;16(16):6599-6611
Food & function 2025 Aug 11;16(16):6599-6611
Effects of Cholesterol Metabolism on Corneal Endothelial Dysfunction in Patients With Type 1 Diabetes.
Ren Z, Li Z, Dou S, Zhao H, Xie L
Investigative ophthalmology & visual science 2025 Aug 1;66(11):9
Investigative ophthalmology & visual science 2025 Aug 1;66(11):9
Celastrol Activates SIRT1/PGC-1α/Nrf2 Axis to Inhibit Oxidative Damage for Subconjunctival Fibrosis Alleviation.
Guo Z, Feng H, Sun X, Yang L, Ning Q, Deng Y, Li Z, Li J
Investigative ophthalmology & visual science 2025 Aug 1;66(11):70
Investigative ophthalmology & visual science 2025 Aug 1;66(11):70
hUC-MSC-derived extracellular vesicles protect lung tissue from cigarette smoke-induced injury by upregulating the METTL3-mediated m(6)A modification.
Wen J, Xu J, Li Y, Ma L, Wang J, Huang S, Yi X
American journal of physiology. Cell physiology 2025 Aug 1;329(2):C426-C439
American journal of physiology. Cell physiology 2025 Aug 1;329(2):C426-C439
Excision repair cross complementation group 1 gene exon 3 skipping isoform presents selective cGAS-STING activation in platinum-sensitive lung adenocarcinoma.
Li L, Xiao M, Zhang L, Zhao S, Zhang G, Wu S, Jin C, Yang J, Lu X
Free radical biology & medicine 2025 Aug 1;235:73-85
Free radical biology & medicine 2025 Aug 1;235:73-85
MSC-derived exosomes alleviate oxidative stress-induced lysosomal membrane permeabilization damage in degenerated nucleus pulposus cells via promoting m6A demethylation of Nrf2.
Gao X, Jia S, Gao L, Chen S, Zhang Y, Liang X, Zhang L, Zhang B, Meng C
Free radical biology & medicine 2025 Aug 1;235:213-230
Free radical biology & medicine 2025 Aug 1;235:213-230
MOSPD1 facilitates fatty acid metabolism and gastric cancer progression by promoting the MAPK pathway.
Wang C, Qiu Y, Zheng X, Chen S, He C
Tissue & cell 2025 Apr;93:102752
Tissue & cell 2025 Apr;93:102752
Dental pulp stem cells derived exosomes inhibit ferroptosis via regulating the Nrf2-keap1/GPX4 signaling pathway to ameliorate chronic kidney disease injury.
Luo L, Wang J, Zhao J, Yang B, Ma W, Lin J
Tissue & cell 2025 Apr;93:102670
Tissue & cell 2025 Apr;93:102670
Functional anti-inflammatory mesoporous silica nanoplatform for Synergistic and Targeted abdominal aortic aneurysm treatment.
Wu Z, Wu X, Meng X, Lei J, Zeng C, Pu H, Liu Y, Xu Z, Wu X, Huang S, Qin J, Liu J, Lu X, Li B
Journal of colloid and interface science 2025 Apr;683(Pt 1):1040-1054
Journal of colloid and interface science 2025 Apr;683(Pt 1):1040-1054
Mechanisms of Differential Sensitivity to Ethanol-Induced Apoptosis in Mouse Spinal Cord at Different Developmental Stages-Akt/GSK Signaling and BAX.
Sun S, Wang Z, Xu X, Ding X, Xu J, Nan X, Li X, Xu J, Ren Z
Molecular neurobiology 2025 Apr;62(4):4301-4318
Molecular neurobiology 2025 Apr;62(4):4301-4318
Porcine epidemic diarrhea virus nsp14 inhibited IFN-Ⅰ production by targeting RIG-I for degradation.
Li S, Wang L, Wen Y, Han J, Hou J, Hou Z, Xie J, Li H, Li X, Yang Y, Feng R
Virology 2025 Apr;605:110451
Virology 2025 Apr;605:110451
Engineered brain-targeting exosome for reprogramming immunosuppressive microenvironment of glioblastoma.
Yang J, Li Y, Jiang S, Tian Y, Zhang M, Guo S, Wu P, Li J, Xu L, Li W, Wang Y, Gao H, Huang Y, Weng Y, Ruan S
Exploration (Beijing, China) 2025 Apr;5(2):20240039
Exploration (Beijing, China) 2025 Apr;5(2):20240039
Autophagy Regulation Attenuates Neuroinflammation and Cognitive Decline in an Alzheimer's Disease Mouse Model with Chronic Cerebral Hypoperfusion.
Yang Q, Yang C, Lv H, Zheng X, Mao S, Liu N, Mo S, Liao B, Yang M, Lu Z, Tang L, Huang X, Jian C, Shang J
Inflammation 2025 Apr;48(2):541-556
Inflammation 2025 Apr;48(2):541-556
Copper doped bioactive glass promotes matrix vesicles-mediated biomineralization via osteoblast mitophagy and mitochondrial dynamics during bone regeneration.
Ling Z, Ge X, Jin C, Song Z, Zhang H, Fu Y, Zheng K, Xu R, Jiang H
Bioactive materials 2025 Apr;46:195-212
Bioactive materials 2025 Apr;46:195-212
Electroacupuncture at 5/100 Hz alleviates neuropathic pain in rats by inhibiting the CCL3/CCR5 axis in the spinal cord.
Wang F, Ye Z, Yin X, Zhou C, Zhong M, Zhao G
Acupuncture in medicine : journal of the British Medical Acupuncture Society 2025 Apr;43(2):95-103
Acupuncture in medicine : journal of the British Medical Acupuncture Society 2025 Apr;43(2):95-103
Olfactory mucosa mesenchymal stem cell-derived exosomes protect against neuroinflammation after subarachnoid hemorrhage by activating mitophagy.
Wang J, Peng J, Gao L, He J, Lin L, Li JM, Xia Y
The Kaohsiung journal of medical sciences 2025 Apr;41(4):e12951
The Kaohsiung journal of medical sciences 2025 Apr;41(4):e12951
Inhibition of Lactate Accumulation via USP38-Mediated MCT1 Deubiquitination Activates AKT/mTOR Signaling to Mitigate PM2.5-Induced Lung Injury.
Chen Z, Cao J, Hou S, Chao L, Li J, Jia Z, Han S, Chen J, Yan X
Journal of clinical laboratory analysis 2025 Apr;39(8):e70028
Journal of clinical laboratory analysis 2025 Apr;39(8):e70028
Exploring the Mechanism of Kai-Xin-San to Improve Cognitive Deficits in AD Rats Induced by D-Gal and Aβ(25-35) Based on Multi-Omics and Network Analysis.
Zhou L, Zhang M, Zheng Q, Song Y, Yan Z, Wang H, Xiong Y, Chen Y, Cai Z, Yuan J
Biomedical chromatography : BMC 2025 Apr;39(4):e70047
Biomedical chromatography : BMC 2025 Apr;39(4):e70047
Heliox alleviates ischemia-reperfusion-induced damage to neuronal cells by repressing the USP46-SNX5 Axis-triggered ferroptosis.
Yang H, Wang Z, Xiong W, Zhou L, Yu S
Experimental neurology 2025 Apr;386:115175
Experimental neurology 2025 Apr;386:115175
miR-484 as an "OncomiR" in Breast Cancer Promotes Tumorigenesis by Suppressing Apoptosis Genes.
Tahtasakal R, Hamurcu Z, Oz AB, Balli M, Dana H, Gok M, Cinar V, Inanc M, Sener EF
Annals of surgical oncology 2025 Apr;32(4):2994-3008
Annals of surgical oncology 2025 Apr;32(4):2994-3008
Self-propelling intelligent nanomotor: A dual-action photothermal and starvation strategy for targeted deep tumor destruction.
Mei L, Ding Q, Xie Y, Liu H, Li H, Kim E, Shen X, Zhang Y, Zhang S, Kim JS
Biomaterials 2025 Apr;315:122968
Biomaterials 2025 Apr;315:122968
Functional poly(ether-ketone-ketone) composite scaffold with enhanced cell-material interaction, anti-inflammatory and osteogenesis for facilitating osteointegration and bone regeneration.
Yang Q, Chen A, Zhang X, Wu Z, Zhang C
Materials today. Bio 2025 Apr;31:101533
Materials today. Bio 2025 Apr;31:101533
Molecular characterization of AMP-activated protein kinase (AMPK) α1/α2 from Cyprinus carpio and its roles in glucolipid metabolism and immune response.
Zhi S, Wang J, Wang Y, Li Y, Zhao M, Yang L, Qin C, Yan X, Nie G
International journal of biological macromolecules 2025 Apr;303:140736
International journal of biological macromolecules 2025 Apr;303:140736
Hyaluronic acid-functionalized nanoparticles enable enhanced chemo/chemodynamic therapy for the targeted treatment of colon cancer.
Liu S, Tong S, Liu G, Wang S, Zhang K, Qiu Z
International journal of biological macromolecules 2025 Apr;303:140553
International journal of biological macromolecules 2025 Apr;303:140553
Sagittaria sagittifolia polysaccharide extract regulates Nrf2 to improve endoplasmic reticulum stress-mediated apoptosis in rat cataracts and HLEB3 cells.
Zhou MY, Liu BQ, Gao X, Zhang SJ, Jiang Y, Yang T, Sun JB, Zhang X, Liao Y
International journal of biological macromolecules 2025 Apr;300:140270
International journal of biological macromolecules 2025 Apr;300:140270
Molecular mechanisms of antiproliferative and pro-apoptotic effects of essential oil active constituents in MCF7 and T24 cancer cell lines: in vitro insights and in silico modelling of proapoptotic gene product-compound interactions.
Saini D, Chaudhary PK, Chaudhary JK, Kaur H, Verma GK, Pramanik SD, Roy P, Mirza-Shariff AA, Prasad R
Apoptosis : an international journal on programmed cell death 2025 Apr;30(3-4):805-825
Apoptosis : an international journal on programmed cell death 2025 Apr;30(3-4):805-825
TNFAIP3-interacting protein 1 (ABIN-1) negatively regulates caspase-8/FADD-dependent pyroptosis.
Li X, Wang D, Su Z, Mao X
The FEBS journal 2025 Apr;292(8):1972-1990
The FEBS journal 2025 Apr;292(8):1972-1990
IRX5 Promoted SREBP1-Mediated de Novo Fatty Acid Synthesis via HMGN4 in Hepatocellular Carcinoma.
Zhu L, Xu Y, Huang C, Li C, Zhang Y, Li X, Pan W, Zeng Z
Journal of cellular and molecular medicine 2025 Apr;29(7):e70441
Journal of cellular and molecular medicine 2025 Apr;29(7):e70441
Integrating network pharmacology and experimental validation to explore the potential mechanism by which resveratrol acts on osimertinib resistance in lung cancer.
Yu X, Yao Y, Zhou H, Zhu J, Zhang N, Sang S, Zhou H
Oncology letters 2025 Apr;29(4):192
Oncology letters 2025 Apr;29(4):192
Multifunctional porous organic polymer-based hybrid nanoparticles for sonodynamically enhanced cuproptosis and synergistic tumor therapy.
Li M, Liu Z, Peng D, Liu Y, Cheng L, Chen B, Liu J
Acta biomaterialia 2025 Apr;196:350-363
Acta biomaterialia 2025 Apr;196:350-363
Cardiomyocyte-specific long noncoding RNA Trdn-as induces mitochondrial calcium overload by promoting the m(6)A modification of calsequestrin 2 in diabetic cardiomyopathy.
Li X, Liu L, Lou H, Dong X, Hao S, Sun Z, Dou Z, Li H, Zhao W, Sun X, Liu X, Zhang Y, Yang B
Frontiers of medicine 2025 Apr;19(2):329-346
Frontiers of medicine 2025 Apr;19(2):329-346
Screening bioactive compounds from Qianghuo (Notopterygium incisum) volatile oil via COX-2 magnetic ligand fishing.
Zhang L, Wu H, Li X, Zhang X, Li H, Tang H, Tang D, Du S, Liu Y, Tang Y, Bao X, Cheng G
Fitoterapia 2025 Apr;182:106432
Fitoterapia 2025 Apr;182:106432
Banxia Xiexin Decoction inhibits colitis-associated colorectal cancer development by modulating STAT3 signaling and gut microbiota.
Yue Y, Su L, Wang Y, Li X, Xiao X, Xie J, Yan S
Chinese herbal medicines 2025 Apr;17(2):380-391
Chinese herbal medicines 2025 Apr;17(2):380-391
Design, synthesis and antitumor activity evaluation of novel modified 18β-glycyrrhetinate derivatives as PPARγ agonists.
Lin H, Cui S, Xu X, Chen Q, Ge J, Ai D, Zhu J, Tao Y, Wang L, Ruan L, Ge W
Bioorganic chemistry 2025 Apr;157:108307
Bioorganic chemistry 2025 Apr;157:108307
EGCG inhibits tobacco smoke-promoted proliferation of lung cancer cells through targeting CCL5.
Dong Z, Wu J, He L, Xie C, Geng S, Wu J, Ji X, Chen X, Zhong C, Li X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156512
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156512
5-hydroxymethylfurfural attenuates osteoarthritis by upregulating of glucose metabolism in chondrocytes.
Wang X, Han X, Ma J, Zhang R, Zou K, Wang X, Yuan W, Qiu M, Chen J, Yang Y, Hu S, Wang X, Jin H, Zhang Y, Wang P
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156499
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156499
Dual role of Baimao-Longdan-Congrong-Fang in inhibiting Staphylococcus aureus virulence factors and regulating TNF-α/TNFR1/NF-κB/MMP9 axis.
Jiang T, Zhu X, Yin Z, Gao R, Li Y, Li C, Meng Q, Zhu X, Song W, Su X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156477
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156477
3-Hydroxypropionaldehyde modulates tryptophan metabolism to activate AhR signaling and alleviate ethanol-induced liver injury.
Liu C, Wang Y, Sheng L, Zhang Y, Luo G, Ruan XZ, Chen Y, Huang M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156445
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156445
Bovine fecal extracellular vesicles: A novel noninvasive tool for understanding gut physiology and pathophysiology in calves.
Premathilaka C, Kodithuwakku S, Midekessa G, Godakumara K, Ul Ain Reshi Q, Andronowska A, Orro T, Fazeli A
Journal of dairy science 2025 Apr;108(4):4116-4130
Journal of dairy science 2025 Apr;108(4):4116-4130
WIPF1 regulates stemness in small cell lung cancer.
Fu H, Quan M, Qiu Q, Jin F
Science progress 2025 Apr-Jun;108(2):368504251345012
Science progress 2025 Apr-Jun;108(2):368504251345012
Fermented Cordyceps Powder alleviates silica-induced inflammation and fibrosis by inhibiting M1 macrophage polarization via the HMGB1-TLR4-NF-κB pathway.
Pu S, Meng X, Shi Y, Huang N, Zhang C, Pang A, Shao H, Jia Q
Journal of ethnopharmacology 2025 Apr 9;345:119631
Journal of ethnopharmacology 2025 Apr 9;345:119631
Shuxuetong injection inhibits pyroptosis in acute ischemic stroke via CD44/NLRP3/GSDMD signal.
Shang J, Huang G, Wang B, Wang J, Wei W, Cui Y, Liu X
Journal of ethnopharmacology 2025 Apr 9;345:119618
Journal of ethnopharmacology 2025 Apr 9;345:119618
Ethyl acetate extract from Herpetospermun cardigerum wall. Ameliorated concanavalin A-induced autoimmune hepatitis in mice by reprofiling gut microenvironment to modulate IDO1/KYN and PI3K/AKT/NF-κB pathways.
Xiao Y, Luo T, Duan C, Wang X, Yang Y, Li R, Deng J, Zhao Q
Journal of ethnopharmacology 2025 Apr 9;345:119578
Journal of ethnopharmacology 2025 Apr 9;345:119578
Dihydromyricetin alleviates ETEC K88-induced intestinal inflammatory injury by inhibiting quorum sensing-related virulence factors.
Shi Y, Liu J, Zhou H, Wu Z, Qiu Y, Ye C
BMC microbiology 2025 Apr 9;25(1):201
BMC microbiology 2025 Apr 9;25(1):201
ELK4 induced upregulation of HOMER3 promotes the proliferation and metastasis in glioma via Wnt/β-catenin/EMT signaling pathway.
Wang F, Zhou H, Tian Y, Wang X, Huang Y, Tu Y, Li L, Zhen H
Biology direct 2025 Apr 9;20(1):48
Biology direct 2025 Apr 9;20(1):48
The Antioxidant Effect of Selenium Is Enhanced by Cortisol Through Nrf2 Pathway in Bovine Endometrial Epithelial Cells.
Cui L, Zhong J, Duan J, Li W, Mao P, Dong J, Liu K, Guo L, Wang H, Li J
Animals : an open access journal from MDPI 2025 Apr 8;15(8)
Animals : an open access journal from MDPI 2025 Apr 8;15(8)
Inhibition of Hepatoblastoma by Ganoderma Lucidum Polysaccharide via the Induction of HDAC4-p16-RB Axis-Mediated Cellular Senescence.
Ye T, Ge Y, Zhang J, Gao H, Zhang PC, Shen R, Peng C, Liu B, Song H
Phytotherapy research : PTR 2025 Apr 6;
Phytotherapy research : PTR 2025 Apr 6;
Targeting the liquid-liquid phase separation of nucleocapsid broadly inhibits the replication of SARS-CoV-2 strains.
Gu L, Wang ZJ, Zhang XR, Liu Y, Zhao M, Jiang SZ, Pan J, Yuan Y, Cai H, Zhou T, Li T, Li TT, Xue W
Biochemical and biophysical research communications 2025 Apr 5;756:151594
Biochemical and biophysical research communications 2025 Apr 5;756:151594
Targeting UAF1 Alleviate Neurotoxicity by Inhibiting APP/NLRP3 Axis-Mediated Pyroptosis and Apoptosis.
Cheng L, Meng X, Tian D, Zheng B, Xiao Y, Zhao X, Xu Y, Yang H, Bi J, Li F, Xie Z
Neurochemical research 2025 Apr 4;50(2):135
Neurochemical research 2025 Apr 4;50(2):135
Analysis of Stratifin Expression and Proteome Variation in a Rat Model of Acute Lung Injury.
Yoshida A, Hashimoto Y, Akane H, Matsuyama S, Toyoda T, Ogawa K, Saito Y, Kikura-Hanajiri R, Arakawa N
Journal of proteome research 2025 Apr 4;24(4):1941-1955
Journal of proteome research 2025 Apr 4;24(4):1941-1955
Acoustic Enrichment Prevents Early Life Stress-Induced Disruptions in Sound Azimuth Processing.
An P, Fang Y, Cheng Y, Liu H, Yang W, Shan Y, de Villers-Sidani E, Zhang G, Zhou X
The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 Apr 30;45(18)
The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 Apr 30;45(18)
F-box protein FBXO32 ubiquitinates and stabilizes D-type cyclins to drive cancer progression.
Li F, Yu H, Zhang Y, Ma Y, Chen X, Zhang J, Sun L, Guo R, Wu Y, Zheng P, Wang X, Bie P, He F, Zhang L, Xie C, Xiong H
Nature communications 2025 Apr 30;16(1):4060
Nature communications 2025 Apr 30;16(1):4060
LncRNA-5829: a novel inhibitor of cardiac fibrosis.
Zhang X, Du Y, Xu J, Zhang W, Wen X, Zhou T, Hong H, Cheng R, Zhang R
Cardiovascular diagnosis and therapy 2025 Apr 30;15(2):302-317
Cardiovascular diagnosis and therapy 2025 Apr 30;15(2):302-317
Hydrogen Sulfide (H(2)S) Mitigates Sepsis-Induced Adrenal Dysfunction via Inhibition of TNFα-Mediated Necroptosis.
Ma K, Huang J, Zhang J, Tian Y, Hu J, Ma L, Wang C
Pathogens (Basel, Switzerland) 2025 Apr 30;14(5)
Pathogens (Basel, Switzerland) 2025 Apr 30;14(5)
Enterohemorrhagic Escherichia coli O157:H7 Infection Inhibits Host Endoplasmic Reticulum Stress in Intestinal Epithelial Cells via the PERK Pathway.
Xu L, Liang S, Wang Y, Gao M, Zhang B, Zhao W, Hua Y, Wan C
Pathogens (Basel, Switzerland) 2025 Apr 30;14(5)
Pathogens (Basel, Switzerland) 2025 Apr 30;14(5)
Ginsenoside CK modulates glucose metabolism via PPARγ to ameliorate SCOP-induced cognitive dysfunction.
Li N, Fang X, Li H, Liu J, Chen N, Zhao X, Yang Q, Chen X
Metabolic brain disease 2025 Apr 3;40(4):168
Metabolic brain disease 2025 Apr 3;40(4):168
The IL-6 autocrine loop promoting IFN-γ-induced fibroblast senescence is involved in psychological stress-mediated exacerbation of vitiligo.
Cao C, Xu W, Lei J, Zheng Y, Zhang A, Xu A, Lin F, Zhou M
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Apr 29;74(1):72
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Apr 29;74(1):72
PKA plays a conserved role in regulating gene expression and metabolic adaptation by phosphorylating Rpd3/HDAC1.
Dai W, Yu Q, Ma R, Zheng Z, Hong L, Qi Y, He F, Wang M, Ge F, Yu X, Li S
Nature communications 2025 Apr 29;16(1):4030
Nature communications 2025 Apr 29;16(1):4030
Targeting prominin-2/BACH1/GLS pathway to inhibit oxidative stress-induced ferroptosis of bone mesenchymal stem cells.
Xu Y, Zhang L, Xu X, Tao Y, Xue P, Wang Y, Chai R, Wu X
Stem cell research & therapy 2025 Apr 29;16(1):213
Stem cell research & therapy 2025 Apr 29;16(1):213
Streptococcus mutans-derived extracellular vesicles promote skin wound healing via tRNA cargo.
Oh SY, Kim DY, Lee KY, Ha DL, Kim TL, Kwon TG, Kim JW, Lee HJ, Choi SY, Hong SH
Journal of nanobiotechnology 2025 Apr 28;23(1):322
Journal of nanobiotechnology 2025 Apr 28;23(1):322
PYK2 promotes cell proliferation and epithelial-mesenchymal transition in endometriosis by phosphorylating Snail1.
Liu L, Liu L, Yue C, Du S, Liu J, Yu Z
Molecular medicine (Cambridge, Mass.) 2025 Apr 27;31(1):155
Molecular medicine (Cambridge, Mass.) 2025 Apr 27;31(1):155
Synergistic Antioxidant and Anti-Ferroptosis Therapy via BPNS-Encapsulated Thermoresponsive Chitosan Hydrogel for Spinal Cord Injury Regeneration.
Liu Y, Wang Y, Wang X, Zeng W, Zhang Z, Zhang Z, Qi Z
Pharmaceutics 2025 Apr 26;17(5)
Pharmaceutics 2025 Apr 26;17(5)
RNA-coupled CRISPR Screens Reveal ZNF207 as a Regulator of LMNA Aberrant Splicing in Progeria.
Behera AK, Kim JJ, Kordale S, Damodaran AP, Kumari B, Vidak S, Dickson E, Xiao MS, Duncan G, Andresson T, Misteli T, Gonatopoulos-Pournatzis T
bioRxiv : the preprint server for biology 2025 Apr 26;
bioRxiv : the preprint server for biology 2025 Apr 26;
Unveiling the multifaceted benefits of Simiao Pill in ulcerative colitis: Integrative analysis of signaling pathways, gut microbiota, and lipid metabolism.
Peng X, Zou Q, Yang C, Pu X, Yang H, Wang M, Chen S, Pu S, Chen X, He H, Li Y
Journal of ethnopharmacology 2025 Apr 25;346:119714
Journal of ethnopharmacology 2025 Apr 25;346:119714
Regulation of monocyte polarization through nuclear factor Kappa B /inhibitor of Kappa B Alpha pathway by Cuscuta chinensis Lam. In postmenopausal osteoporosis.
Li X, Wang Z, Chen Y, Yang Y, Shao H, Feng X, Ren Y
Journal of ethnopharmacology 2025 Apr 25;346:119710
Journal of ethnopharmacology 2025 Apr 25;346:119710
TAK-242 attenuates NLRP3-ASC inflammasome-mediated neuroinflammation via TLR4/NF-κB pathway in rat experimental autoimmune neuritis.
Li X, Yang L, Kang X, Wang G, Yuan Y, Yang H, Yang T, Wang Z
International immunopharmacology 2025 Apr 24;153:114429
International immunopharmacology 2025 Apr 24;153:114429
Kanglexin attenuates spinal cord injury by modulating pyroptosis and polarization via the PKA/NF-κB signaling pathway.
Yan R, Yuan Y, Shi C, Li Y, Li Y, Wang W, Yang L
International immunopharmacology 2025 Apr 24;153:114401
International immunopharmacology 2025 Apr 24;153:114401
Ilex latifolia Improves the Anti-Tumor Effectiveness of Rapamycin Against Breast Cancer In Vitro and In Vivo.
Ren Z, Wu Y, Guo X, Tian H, Ou H, Xiong Z, Xiao Y, Xiao L, Li J, Wu H, Wang X
Foods (Basel, Switzerland) 2025 Apr 24;14(9)
Foods (Basel, Switzerland) 2025 Apr 24;14(9)
Antiviral Activity of 1-Deoxynojirimycin Extracts of Mulberry Leaves Against Porcine Epidemic Diarrhea Virus.
Sun Y, Wang L, Ma K, Shen M, Liu J, Zhang Y, Sun L
Animals : an open access journal from MDPI 2025 Apr 23;15(9)
Animals : an open access journal from MDPI 2025 Apr 23;15(9)
SWI/SNF complex-mediated ZNF410 cooperative binding maintains chromatin accessibility and enhancer activity.
Xu S, Peng C, Ren R, Lu H, Zhao H, Xia S, Shen Y, Xu B, Zhang H, Cheng X, Blobel GA, Lan X
Cell reports 2025 Apr 22;44(4):115476
Cell reports 2025 Apr 22;44(4):115476
Dual Disruption of EGFR/PI3K Signaling: IGF2BP2 Targeting Reverses Anti-EGFR Resistance in CAFs-Infiltrated Oral Squamous Cell Carcinoma.
Hu Y, Zhu T, Nong S, Sun Y, Li Y, Pan J, Ma J, Zhang J
International journal of molecular sciences 2025 Apr 22;26(9)
International journal of molecular sciences 2025 Apr 22;26(9)
Orthodontic treatment after occlusal intervention balances osteoblast and osteoclast differentiation via SIRT1 beta catenin signaling in rats with hypofunctional occlusion.
Ji J, Zhou Z, Zhu Y, Wang R, Liu Y
Scientific reports 2025 Apr 22;15(1):13872
Scientific reports 2025 Apr 22;15(1):13872
MicroRNA-30a-3p Influences Milk Fat Metabolism by Targeting PTEN in Mammary Epithelial Cells of Sheep.
Guo Y, Wu X, Zhen H, Feng Y, Li M, Ren C, Wang J, Hao Z
Animals : an open access journal from MDPI 2025 Apr 20;15(8)
Animals : an open access journal from MDPI 2025 Apr 20;15(8)
CD147 regulates the Rap1 signaling pathway to promote proliferation, migration, and invasion, and inhibit apoptosis in colorectal cancer cells.
Xiaoxia F, Rui L, Meiru C, Lu Y, Ying J
Scientific reports 2025 Apr 20;15(1):13647
Scientific reports 2025 Apr 20;15(1):13647
S100A9 as a promising therapeutic target for diabetic foot ulcers.
Wan R, Fang S, Zhang X, Zhou W, Bi X, Yuan L, Lv Q, Song Y, Tang W, Shi Y, Li T
Chinese medical journal 2025 Apr 20;138(8):973-981
Chinese medical journal 2025 Apr 20;138(8):973-981
Hydrogen sulfide improves poststroke depression-induced inflammation in microglial cells by enhancing endoplasmic reticulum autophagy and inhibiting the cGAS-STING pathway.
Luo B, Xie Y, Kuang W, Wang Y, Chen G, Zhang Y, Yuan M
Neuroreport 2025 Apr 2;36(6):314-326
Neuroreport 2025 Apr 2;36(6):314-326
Y4 RNA fragment alleviates myocardial injury in heart transplantation via SNRNP200 to enhance IL-10 mRNA splicing.
Lu C, Meng Z, Tang S, Wei H, Hu Y, Chen D, Liu D, Wen H, Dong K, Na N, Huang F, Zeng Z
Molecular therapy : the journal of the American Society of Gene Therapy 2025 Apr 2;33(4):1735-1748
Molecular therapy : the journal of the American Society of Gene Therapy 2025 Apr 2;33(4):1735-1748
P4HA1 is highly expressed in gastric cancer and promotes proliferation and metastasis of gastric cancer cells.
Gao P, Tian H, Ge K, Wang F, Zhao Y, Sun J, Zhang Q
Discover oncology 2025 Apr 19;16(1):575
Discover oncology 2025 Apr 19;16(1):575
PDZK1 inhibits MRP2-mediated oxaliplatin chemosensitivity in hepatocellular carcinoma.
Duan Z, Li J, Ren C, Chen Y, Feng D, Ma Y, Zhao C
Scientific reports 2025 Apr 18;15(1):13438
Scientific reports 2025 Apr 18;15(1):13438
RAGE deficiency ameliorates abdominal aortic aneurysm progression.
Bi C, Liu B, Gao P, Wang C, Fang S, Huo Z, Song Q, Dong D, Wu X, Li G
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Apr 17;74(1):63
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Apr 17;74(1):63
PRC1 as an independent adverse prognostic factor in Wilms tumor via integrated bioinformatics and experimental validation.
Wang Y, Gao H, Li X, Li D, Huang F, Sun Y, Liu X, Yang J, Sun F
Scientific reports 2025 Apr 17;15(1):13282
Scientific reports 2025 Apr 17;15(1):13282
Green Tea Ameliorates Depression-Like Behavior and Cognitive Impairment Induced by High-Fat Diet and Chronic Mild Stress.
Fan M, Jiang Y, Cai C, Wang Z, Chen L, Hu S, Zhang X, Yin H, Qian Z, Huang S, Yang J
Phytotherapy research : PTR 2025 Apr 17;
Phytotherapy research : PTR 2025 Apr 17;
Wogonoside ameliorates oxidative damage in tubular epithelial cells of diabetic nephropathy by modulating the HNF4A-NRF2 axis.
Li X, Zhao S, Li M, Xing X, Xie J, Wang M, Xu A, Zhao Q, Zhang J
International immunopharmacology 2025 Apr 16;152:114481
International immunopharmacology 2025 Apr 16;152:114481
Oleanolic acid inhibits mesangial cell proliferation and inflammatory response in mesangial proliferative glomerulonephritis through IL-17/ERK/AKT pathway.
Pan D, Xia J, Qu Y, Shi C, Du H, Zhang J, Peng F, Wang X, Liu R, Wu L, Hong Q, Chen X
International immunopharmacology 2025 Apr 16;152:114459
International immunopharmacology 2025 Apr 16;152:114459
UBTF facilitates acute myeloid leukemia development and immune escape via PD-L1 regulation.
Yang C, Wan J, Wang Y, Yang Y, Ran Y, Zhang F, Zhou M, Liu P, Kang Q, Ma D, Yang X
International immunopharmacology 2025 Apr 16;152:114433
International immunopharmacology 2025 Apr 16;152:114433
TLR4-mediated endoplasmic reticulum stress regulates pyroptosis in macrophages infected with the Bacillus Calmette-Guérin mycobacterial.
Nie X, Miao S, Hou Y, Ma Y, Li M, Liu Y, Yang Y, Xu J, Wang Y
International immunopharmacology 2025 Apr 16;152:114346
International immunopharmacology 2025 Apr 16;152:114346
The interaction between IL-33 and TRIM28 in the regulation of macrophage polarization in an ST2-independent manner.
Zhao Y, Xu H, Liu Q, Yuan Y, Li R, Li D, Zhang Y, Ran J, Yan X, Su J
International immunopharmacology 2025 Apr 16;152:114318
International immunopharmacology 2025 Apr 16;152:114318
GPR37L1 identifies spinal cord astrocytes and protects neuropathic pain after nerve injury.
Xu J, Yan Z, Bang S, Velmeshev D, Ji RR
Neuron 2025 Apr 16;113(8):1206-1222.e6
Neuron 2025 Apr 16;113(8):1206-1222.e6
Discovery of Airway-Administered Ionophores for Mn(2+) to Mitigate Lung Metastasis by Targeting Disseminated Tumor Cell.
Wang Y, Fan N, Wang R, Li X, Zhao F, Miao L, Wang X, Yan X, Zhang Z, Wu X, Gao Z, Li Y, Li Y
ACS nano 2025 Apr 15;19(14):14330-14350
ACS nano 2025 Apr 15;19(14):14330-14350
Total ginsenosides from wild ginseng improve immune regulation in a rat model of spleen qi deficiency by modulating fecal-bacteria-associated short-chain fatty acids and intestinal barrier integrity.
Bai R, Ma L, Li F, Pan L, Bao Y, Li X, Wang S, Yue H, Zheng F
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2025 Apr 15;1256:124554
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2025 Apr 15;1256:124554
Aberrant expression of TRIM44, transcriptionally regulated by KLF9, contributes to the process of diabetic retinopathy.
Han N, Yu N, Yu L
Journal of translational medicine 2025 Apr 11;23(1):433
Journal of translational medicine 2025 Apr 11;23(1):433
CDC25A inhibition sensitizes melanoma cells to doxorubicin and NK cell therapy.
Gao X, Liu F, Zhang B, Ren T, Zheng Y, Niu Z, Ren H, Liu C, Jiang C, Wang C, Huang H, Ma L, Sun Q
Cell death & disease 2025 Apr 11;16(1):276
Cell death & disease 2025 Apr 11;16(1):276
Silicate-based therapy for inflammatory dilated cardiomyopathy by inhibiting the vicious cycle of immune inflammation via FOXO signaling.
Sun P, Zhang Z, Gao F, Yang C, Mang G, Fu S, Tian J, Chang J
Science advances 2025 Apr 11;11(15):eadr7208
Science advances 2025 Apr 11;11(15):eadr7208
Tannic acid‑cerium nanoenzymes serve as broad-spectrum antioxidants to alleviate acute kidney injury by modulating macrophage polarization, mitophagy and endoplasmic reticulum stress.
Fu H, Wang Y, Huang B, Liang Z, Li Y, Cao Z, Wu J, Zhao Y
Journal of controlled release : official journal of the Controlled Release Society 2025 Apr 10;380:892-909
Journal of controlled release : official journal of the Controlled Release Society 2025 Apr 10;380:892-909
5-Aminolevulinic Acid: A Novel Approach to Improving Radioresistance in Prostate Cancer.
Maesaka F, Nakai Y, Yoshida T, Tomizawa M, Shimizu T, Owari T, Onishi K, Miyake M, Kuniyasu H, Fujimoto K, Tanaka N
Cancers 2025 Apr 10;17(8)
Cancers 2025 Apr 10;17(8)
Expression Distribution of Keratins in Normal and Pathological Corneas and the Regulatory Role of Krt17 on Limbal Stem Cells.
Wang M, Chen R, Wang Y, Li Y, Zhou Q, Cao R, Li Y, Ge H, Wang X, Yang L
Investigative ophthalmology & visual science 2025 Apr 1;66(4):55
Investigative ophthalmology & visual science 2025 Apr 1;66(4):55
Triclosan exposure induces liver fibrosis in mice: The heterogeneous nuclear ribonucleoprotein A1/pyruvate kinase M2 axis drives hepatic stellate cell activation.
Ni X, Wei Z, Peng Y, Zheng L, Shang J, Liu F, Li Y, Liu J
Ecotoxicology and environmental safety 2025 Apr 1;294:118113
Ecotoxicology and environmental safety 2025 Apr 1;294:118113
REGγ deficiency ameliorates hepatic ischemia and reperfusion injury in a mitochondrial p66shc dependent manner in mice.
Guo L, Yang Q, Zhu J, Li J
Translational gastroenterology and hepatology 2024;9:62
Translational gastroenterology and hepatology 2024;9:62
Tanshinone IIA alleviates IL-1β-induced chondrocyte apoptosis and inflammation by regulating FBXO11 expression.
Xu J, Zhi X, Zhang Y, Ding R
Clinics (Sao Paulo, Brazil) 2024;79:100365
Clinics (Sao Paulo, Brazil) 2024;79:100365
Activable Photodynamic DNA Probe with an "AND" Logic Gate for Precision Skin Cancer Therapy.
Zhu J, Peng L, Jehan S, Wang H, Chen X, Zhao S, Zhou W
Research (Washington, D.C.) 2024;7:0295
Research (Washington, D.C.) 2024;7:0295
B-Type Natriuretic Peptide Inhibits the Expression and Function of SERCA2a in Heart Failure.
Zhai Y, Chen J, Kan R, Xuan H, Wang C, Li D, Xu T
International heart journal 2024;65(2):292-299
International heart journal 2024;65(2):292-299
Deoxycholic acid aggravates necrotizing enterocolitis through downregulation of mesenchymal-epithelial transition factor expression.
Li H, Lai J, Xiao D, Huang D, Zhang Y, Gu X, Li F, Hao H
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2024;57:e14046
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2024;57:e14046
Isoliquiritigenin Suppresses Breast Tumor Development by Enhancing Host Antitumor Immunity.
Yuan CL, Yang XL, Sun L, Jiang YX, Zhang DD, Huang S
The American journal of Chinese medicine 2024;52(6):1819-1841
The American journal of Chinese medicine 2024;52(6):1819-1841
Astragaloside I from Astragalus Attenuates Diabetic Kidney Disease by Regulating HDAC3/Klotho/TGF-β1 Loop.
Zhang X, Wang J, Xiang S, Zhao L, Lv M, Duan Y, Gao G, Wang P, Jie Chen J, Xu J, Xie Z, Zhang Z
The American journal of Chinese medicine 2024;52(6):1795-1817
The American journal of Chinese medicine 2024;52(6):1795-1817
Therapeutic Potential of Danyankang Capsule in High-Fat Diet-Induced Cholelithiasis and Its Impact on Liver FXR Signaling and Gut Microbiota.
Zhou L, Zhang CL, Jiang K, Cheng HY, Xiong WW, Zhu JX
Biological & pharmaceutical bulletin 2024;47(3):680-691
Biological & pharmaceutical bulletin 2024;47(3):680-691
IL13RA2 promotes progression of infantile haemangioma by activating glycolysis and the Wnt/β-catenin signaling pathway.
Liu Z, Ma T, Li J, Ren W, Zhang Z
Oncology research 2024;32(9):1453-1465
Oncology research 2024;32(9):1453-1465
Integrative bioinformatics and in vitro exploration of EVI2A expression: unraveling its immunological and prognostic implications in kidney renal clear cell carcinoma.
Liu R, Li S, Xiong S, Zheng F, Zhan X, Zeng J, Fu B, Xu S, Zhu S, Chen RU
Oncology research 2024;32(11):1733-1746
Oncology research 2024;32(11):1733-1746
Leukemia Inhibitory Factor Protects against Degeneration of Cone Photoreceptors Caused by RPE65 Deficiency.
Dong S, Zhen F, Zou T, Zhou Y, Wu J, Wang T, Zhang H
Current medicinal chemistry 2024;31(25):4022-4033
Current medicinal chemistry 2024;31(25):4022-4033
Custom-Made Ce-Mn Bimetallic Nanozyme for the Treatment of Intervertebral Disc Degeneration by Inhibiting Oxidative Stress and Modulating Macrophage M1/M2 Polarization.
Wu J, Chen Z, Huang H, Wang H, Wang X, Lu Z, Xu H, Ma X, Zeng F, Wang H
Biomaterials research 2024;28:0118
Biomaterials research 2024;28:0118
Cadmium-induced annulus fibrosus cell senescence contributes to intervertebral disc degeneration via the JNK/p53 signaling pathway.
Liu X, Zhao W, Hu M, Zhang Y, Wang J, Zhang L
Iranian journal of basic medical sciences 2024;27(5):588-595
Iranian journal of basic medical sciences 2024;27(5):588-595
The Mechanism of Action and Experimental Verification of Narenmandula in the Treatment of Postmenopausal Osteoporosis.
Xiao J, Yu Z, Han Q, Guo Y, Ye J, Lian H, Wang L, Ma Y, Liu M
Combinatorial chemistry & high throughput screening 2024;27(15):2249-2259
Combinatorial chemistry & high throughput screening 2024;27(15):2249-2259
mirna-383-5p Functions as an Anti-oncogene in Glioma through the Akt/mTOR Signaling Pathway by Targeting VEGFA.
Liu Y, Wang Z, Tang Z, Fu Y, Wang L
Current cancer drug targets 2024;24(4):463-475
Current cancer drug targets 2024;24(4):463-475
CAPN5 attenuates cigarette smoke extract-induced apoptosis and inflammation in BEAS-2B cells.
Li H, Ma Y, Li T, Zeng Z, Luo L, Liu X, Li Y, Chen Y
Tobacco induced diseases 2024;22
Tobacco induced diseases 2024;22
N-cadherin Alleviates Apoptosis and Senescence of Nucleus Pulposus Cells via Suppressing ROS-dependent ERS in the Hyper-osmolarity Microenvironment.
Zou L, Wang Y, Hu Y, Liu L, Luo L, Chen Z, Zhuo Y, Li P, Zhou Q
International journal of medical sciences 2024;21(2):341-356
International journal of medical sciences 2024;21(2):341-356
Aortic calcification accelerates cardiac dysfunction via inducing apoptosis of cardiomyocytes.
Hao N, Yong H, Zhang F, Liu C, Qiu Y, Shi Y, Li C, Wang F
International journal of medical sciences 2024;21(2):306-318
International journal of medical sciences 2024;21(2):306-318
Resveratrol Mitigates Uremic Toxin-Induced Intestinal Barrier Dysfunction in Chronic Kidney Disease by Promoting Mitophagy and Inhibiting Apoptosis Pathways.
Zheng CM, Hou YC, Tsai KW, Hu WC, Yang HC, Liao MT, Lu KC
International journal of medical sciences 2024;21(13):2437-2449
International journal of medical sciences 2024;21(13):2437-2449
Attenuation of palmitic acid-induced lysyl oxidase overexpression in the ovary contributes to the improvement of ovulation in obesity by metformin.
Zhang C, Wang WS, Yao G, Zhu Y, Lin Y, Lu J, Sun K, Sun Y
Human reproduction open 2024;2024(1):hoae002
Human reproduction open 2024;2024(1):hoae002
Shikonin Induces Autophagy and Apoptosis in Esophageal Cancer EC9706 Cells by Regulating the AMPK/mTOR/ULK Axis.
Zhang J, Guo J, Gu B, Wang F, Li Y, Shang L, Jiang W, Ma J, Wu W
Analytical cellular pathology (Amsterdam) 2024;2024:7752299
Analytical cellular pathology (Amsterdam) 2024;2024:7752299
Role of the NOD1/Rip2 Signaling Pathway in Macrophage Inflammatory Activation Induced by ox-LDL.
Hou L, Liu J, Yuan Y, Ding Y
Cardiology research and practice 2024;2024:7601261
Cardiology research and practice 2024;2024:7601261
Dietary Fiber-Derived Microbial Butyrate Suppresses ILC2-Dependent Airway Inflammation in COPD.
Jiang M, Wang J, Li Z, Xu D, Jing J, Li F, Ding J, Li Q
Mediators of inflammation 2024;2024:6263447
Mediators of inflammation 2024;2024:6263447
Mesenchymal Stem Cells Accelerate Recovery of Acetic Acid-Induced Chronic Gastric Ulcer by Regulating Ekt/Akt/TRIM29 Axis.
Zhao F, Fan Z, Jia R, Liu Q, Wang M, Sui J, Liu H
Stem cells international 2024;2024:6202123
Stem cells international 2024;2024:6202123
ITGA1 Promotes Glioma Cell Proliferation and Affects Immune Cell Infiltration in Low-Grade Glioma.
Ren Y, Xu J, Zhang Z, Yu R
Mediators of inflammation 2024;2024:6147483
Mediators of inflammation 2024;2024:6147483
Exploring the Analgesic Initiation Mechanism of Tuina in the Dorsal Root Ganglion of Minor CCI Rats via the TRPV1/TRPA1-cGMP Pathway.
Yang Z, Sa C, Yu T, Chen J, Zhang R, Zhang Y, Liu J, Zhang H, Sun J
Pain research & management 2024;2024:2437396
Pain research & management 2024;2024:2437396
HMGB1 Modulates High Glucose-Induced Erroneous Differentiation of Tendon Stem/Progenitor Cells through RAGE/β-Catenin Pathway.
Lu P, Dai G, Shi L, Li Y, Zhang M, Wang H, Rui Y
Stem cells international 2024;2024:2335270
Stem cells international 2024;2024:2335270
The m6A modification-mediated positive feedback between glycolytic lncRNA SLC2A1-DT and c-Myc promotes tumorigenesis of hepatocellular carcinoma.
Zeng Z, Wang J, Xu F, Hu P, Hu Y, Zhuo W, Chen D, Han S, Wang F, Zhao Y, Huang Y, Zhao G
International journal of biological sciences 2024;20(5):1744-1762
International journal of biological sciences 2024;20(5):1744-1762
Sirtuin 4 (Sirt4) downregulation contributes to chondrocyte senescence and osteoarthritis via mediating mitochondrial dysfunction.
Lin S, Wu B, Hu X, Lu H
International journal of biological sciences 2024;20(4):1256-1278
International journal of biological sciences 2024;20(4):1256-1278
IKBKE regulates renal cell carcinoma progression and sunitinib resistance through the RRM2-AKT pathway.
Liu S, Li J, Zhang J, Wan F, Hong Z, Hong Z, Dai B
International journal of biological sciences 2024;20(15):6146-6161
International journal of biological sciences 2024;20(15):6146-6161
HSPD1 Supports Osteosarcoma Progression through Stabilizing ATP5A1 and thus Activation of AKT/mTOR Signaling.
Zhang Y, Pan R, Li K, Cheang LH, Zhao J, Zhong Z, Li S, Wang J, Zhang X, Cheng Y, Zheng X, He R, Wang H
International journal of biological sciences 2024;20(13):5162-5190
International journal of biological sciences 2024;20(13):5162-5190
KIF15 promotes human glioblastoma progression under the synergistic transactivation of REST and P300.
Yu W, Han S, Hu S, Ru L, Hua C, Xue G, Zhang G, Lv K, Ge H, Wang M, Zheng L, Zhou J, Hou S, Teng Y, Deng W, Guo W
International journal of biological sciences 2024;20(13):5127-5144
International journal of biological sciences 2024;20(13):5127-5144
Dual role of CD73 as a signaling molecule and adenosine-generating enzyme in colorectal cancer progression and immune evasion.
Lian W, Jiang D, Lin W, Jiang M, Zhang Y, Wang H, Zhao L
International journal of biological sciences 2024;20(1):137-151
International journal of biological sciences 2024;20(1):137-151
RETRACTED: Curcumin alleviates osteoarthritis in mice by suppressing osteoclastogenesis in subchondral bone via inhibiting NF-κB/JNK signaling pathway.
Ding D, Liu G, Yan J, Zhang Q, Meng F, Wang L
PloS one 2024;19(9):e0309807
PloS one 2024;19(9):e0309807
Mesoporous zinc-polyphenol nanozyme for attenuating renal ischemia-reperfusion injury.
Li Z, Qin J, Feng Y, Ding C, Guo Y, Zhao Z, Sun S, Zheng J, Zhang M, Zhang J, Zhang Y, Wei J, Xue W
Nanomedicine (London, England) 2024;19(24):2011-2026
Nanomedicine (London, England) 2024;19(24):2011-2026
miR-328-3p targets TLR2 to ameliorate oxygen-glucose deprivation injury and neutrophil extracellular trap formation in HUVECs via inhibition of the NF-κB signaling pathway.
Yao M, Fang C, Wang Z, Guo T, Wu D, Ma J, Wu J, Mo J
PloS one 2024;19(2):e0299382
PloS one 2024;19(2):e0299382
Circular RNA circ-CARD8 regulates alveolar macrophage pyroptosis through the miR-580-3p/CARD8 pathway in acute lung injury.
Chen S, Wen L, Wu Y, Xiao S, Lai Y, Ou J, Shen Y
PloS one 2024;19(12):e0314936
PloS one 2024;19(12):e0314936
GLP-1RA improves diabetic renal injury by alleviating glomerular endothelial cells pyrotosis via RXRα/circ8411/miR-23a-5p/ABCA1 pathway.
Wu W, Wang Y, Shao X, Huang S, Wang J, Zhou S, Liu H, Lin Y, Yu P
PloS one 2024;19(12):e0314628
PloS one 2024;19(12):e0314628
ADAR1 plays a protective role in proximal tubular cells under high glucose conditions by attenuating the PI3K/AKT/mTOR signaling pathway.
Wang Y, Chang J, Wang F, Lai L, Yang S, Fu Y, Ma X, Yun C
Open medicine (Warsaw, Poland) 2024;19(1):20241037
Open medicine (Warsaw, Poland) 2024;19(1):20241037
Therapeutic Effects of Lifei Decoction in a Murine Model of COPD Induced by LPS and Cigarette Smoke.
Lu L, Zhu C, Xu J, Hu Y, Dai J, Wang S, Wei T
International journal of chronic obstructive pulmonary disease 2024;19:957-967
International journal of chronic obstructive pulmonary disease 2024;19:957-967
Novel L-(CaP-ZnP)/SA Nanocomposite Hydrogel with Dual Anti-Inflammatory and Mineralization Effects for Efficient Vital Pulp Therapy.
Zhang X, Zhou X, Zhai W, Cui J, Pan Z, Du L, Wen L, Ye R, Zhang B, Huang L, Li D, Wang C, Sun H
International journal of nanomedicine 2024;19:6659-6676
International journal of nanomedicine 2024;19:6659-6676
Localized Administration of Bcar3 siRNA via Nano-Self-Assembly to Treat Idiopathic Pulmonary Fibrosis by Disrupting Macrophage-Fibroblast Crosstalk.
Zeng C, Wang Q, Liu X, Wang K, Wang C, Ju X, Wang T, Zhou Q, Fu X, Yu J, Wang Y
International journal of nanomedicine 2024;19:1827-1842
International journal of nanomedicine 2024;19:1827-1842
Cigarette Smoke Extract Induces MUC5AC Expression Through the ROS/ IP3R/Ca(2+) Pathway in Calu-3 Cells.
Wu X, Zhang G, Du X
International journal of chronic obstructive pulmonary disease 2024;19:1635-1647
International journal of chronic obstructive pulmonary disease 2024;19:1635-1647
Pretreatment of Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes with Quercetin Enhances the Healing of Diabetic Skin Wounds by Modulating Host-Microbiota Interactions.
Wu S, Zhou Z, Li Y, Wu R, Jiang J
International journal of nanomedicine 2024;19:12557-12581
International journal of nanomedicine 2024;19:12557-12581
16S rRNA Gene Sequencing Combined with Metabolomics to Explore Intestinal Flora and Metabolic Changes in Young Febrile Rats and the Mechanism of Xiangqin Jiere Granules.
He X, Pan M, Wu X, Li H, Xi Y, Zhang L, Zhang Y, Tian Y, Wang R, Xiong L
Drug design, development and therapy 2024;18:5423-5444
Drug design, development and therapy 2024;18:5423-5444
Imperatorin Suppresses Aberrant Hedgehog Pathway and Overcomes Smoothened Antagonist Resistance via STAT3 Inhibition.
Wang J, Cheng H, Zhao X, Zhang X, Ding X, Huang T
Drug design, development and therapy 2024;18:5307-5322
Drug design, development and therapy 2024;18:5307-5322
Obacunone Alleviates Inflammatory Pain by Promoting M2 Microglial Polarization and by Activating Nrf2/HO-1 Signaling Pathway.
Nan F, Tian Q, Chen S
Drug design, development and therapy 2024;18:1265-1275
Drug design, development and therapy 2024;18:1265-1275
Cholinergic Anti-inflammatory Pathway Attenuates Acute Liver Failure Through Inhibiting MAdCAM1/α4β7-mediated Gut-derived Proinflammatory Lymphocytes Accumulation.
Fu S, Ni T, Zhang M, Ren D, Feng Y, Yao N, Zhang X, Wang R, Xu W, Yang N, Yang Y, He Y, Zhao Y, Liu J
Cellular and molecular gastroenterology and hepatology 2024;17(2):199-217
Cellular and molecular gastroenterology and hepatology 2024;17(2):199-217
Ube2L6 Promotes M1 Macrophage Polarization in High-Fat Diet-Fed Obese Mice via ISGylation of STAT1 to Trigger STAT1 Activation.
Li Y, Dong X, He W, Quan H, Chen K, Cen C, Wei W
Obesity facts 2024;17(1):24-36
Obesity facts 2024;17(1):24-36
Regulation of Inflammation, Lipid Metabolism, and Liver Fibrosis by Core Genes of M1 Macrophages in NASH.
Xu X, Dong Y, Liu J, Zhang P, Yang W, Dai L
Journal of inflammation research 2024;17:9975-9986
Journal of inflammation research 2024;17:9975-9986
A Neutrophil Extracellular Traps-Related Gene Trait Revealed the Prospective Therapy Strategy of Coronary Atherosclerosis.
Li Z, Zhao W, Ji W, Li Z, Wang K, Jiang T
Journal of inflammation research 2024;17:9925-9951
Journal of inflammation research 2024;17:9925-9951
Arctiin Alleviates Atopic Dermatitis Against Inflammation and Pyroptosis Through Suppressing TLR4/MyD88/NF-κB and NLRP3/Caspase-1/GSDMD Signaling Pathways.
Li J, Du X, Mu Z, Han X
Journal of inflammation research 2024;17:8009-8026
Journal of inflammation research 2024;17:8009-8026
MicroRNA-204-5p Ameliorates Renal Injury via Regulating Keap1/Nrf2 Pathway in Diabetic Kidney Disease.
Dong J, Liu M, Bian Y, Zhang W, Yuan C, Wang D, Zhou Z, Li Y, Shi Y
Diabetes, metabolic syndrome and obesity : targets and therapy 2024;17:75-92
Diabetes, metabolic syndrome and obesity : targets and therapy 2024;17:75-92
Claudin-2 Mediates the Proximal Tubular Epithelial Cell-Fibroblast Crosstalk via Paracrine CTGF.
Guo C, Jiao M, Cui Y, Li P, Yao J, Dong J, Liao L
Diabetes, metabolic syndrome and obesity : targets and therapy 2024;17:55-73
Diabetes, metabolic syndrome and obesity : targets and therapy 2024;17:55-73
Angiotensin-(1-7) Modulates the Warburg Effect to Alleviate Inflammation in LPS-Induced Macrophages and Septic Mice.
Yu D, Huang W, Sheng M, Zhang S, Pan H, Ren F, Luo L, Zhou J, Huang D, Tang L
Journal of inflammation research 2024;17:469-485
Journal of inflammation research 2024;17:469-485
Network Pharmacology-Based Strategy to Explore the Effect and Mechanism of Zhizhu Granule Improving Glucose-Lipid Metabolism in Rats with Metabolic Syndrome.
Wang J, Liu Y, Xiu C, Wang X, Liu Y, Hu Y, Yang J, Lei Y
Diabetes, metabolic syndrome and obesity : targets and therapy 2024;17:3833-3846
Diabetes, metabolic syndrome and obesity : targets and therapy 2024;17:3833-3846
Expression Analysis of VPS72 and Associated Biological Behaviors in Colon Cancer.
Cao J, Zhang H, Xie X, Wang W
International journal of general medicine 2024;17:3433-3442
International journal of general medicine 2024;17:3433-3442
High expression of COPZ2 is associated with poor prognosis and cancer progression in glioma.
Geng Z, Mu C, Qiu Y, Tang Y, Su M, Tang C, Zhang L
Frontiers in molecular neuroscience 2024;17:1438135
Frontiers in molecular neuroscience 2024;17:1438135
Quercetin Protects Against Global Cerebral ischemia‒reperfusion Injury by Inhibiting Microglial Activation and Polarization.
Wang N, Li F, Du J, Hao J, Wang X, Hou Y, Luo Z
Journal of inflammation research 2024;17:1281-1293
Journal of inflammation research 2024;17:1281-1293
Methyl Cinnamate (MC) Alleviates Free Fatty Acids (FFAs) Induced Lipid Accumulation Through the AMPK Pathway in HepG2 Cells.
Fu Y, Li G, Feng Z, Liu J, Wang X, Wang T, Liu J
Diabetes, metabolic syndrome and obesity : targets and therapy 2024;17:1183-1197
Diabetes, metabolic syndrome and obesity : targets and therapy 2024;17:1183-1197
Identification of Macrophage-Related Biomarkers for Abdominal Aortic Aneurysm Through Combined Single-Cell Sequencing and Machine Learning.
Yao G, Hu X, Song D, Yao J, Chen D, Luan T, Zhao Y
Journal of inflammation research 2024;17:11009-11027
Journal of inflammation research 2024;17:11009-11027
Cistanche deserticola polysaccharide alleviates constipation by regulating intestinal barrier function and intestinal microbiota and their metabolites.
Yu Z, Zhang Z, Hu C, Xie L, Zhang R, Gao R, Zhang Z, Wei X, Li T, Guo J
American journal of translational research 2024;16(11):7036-7053
American journal of translational research 2024;16(11):7036-7053
THSR Mediated MiR374b Targeting C/EBP β/FOXO1 to Accelerate Thyroid Stimulating Hormone-Induced Hepatic Steatosis.
Li J, Ge Y, Chai Y, Kou C, Sun TT, Liu J, Zhang H
Hepatic medicine : evidence and research 2024;16:91-104
Hepatic medicine : evidence and research 2024;16:91-104
Identification and experimental validation of ferroptosis-related gene lactotransferrin in age-related hearing loss.
Zeng C, Gu X, Chen Y, Lin Y, Chen J, Chen Z, Chen C, Yao G, Lin C
Frontiers in aging neuroscience 2024;16:1309115
Frontiers in aging neuroscience 2024;16:1309115
SP1 Mediated PIK3CB Upregulation Promotes Gastric Carcinogenesis.
Fan K, Hu Q, Yu S, Gao Y, Li Y
Journal of Cancer 2024;15(5):1355-1365
Journal of Cancer 2024;15(5):1355-1365
Synergistic Anti-Tumor Efficacy Achieved by Reversing Drug Resistance through the Regulation of the Tumor Immune Microenvironment with IL-12 and Osimertinib Combination Therapy.
Ding H, Wu L, Qin H, Fu W, Wang Y, Wu M, Wang J, Han Y
Journal of Cancer 2024;15(14):4534-4550
Journal of Cancer 2024;15(14):4534-4550
ACOX2 Serves as a Favorable Indicator Related to Lipid Metabolism and Oxidative Stress for Biochemical Recurrence in Prostate Cancer.
Tan Z, Deng Y, Cai Z, He H, Tang Z, Feng Y, Ye J, Liu R, Cai S, Huang H, Han Z, Zhong W, Guo K
Journal of Cancer 2024;15(10):3010-3023
Journal of Cancer 2024;15(10):3010-3023
High expression of malic enzyme 1 predicts adverse prognosis in patients with cytogenetically normal acute myeloid leukaemia and promotes leukaemogenesis through the IL-6/JAK2/STAT3 pathways.
Zhang C, Li W, Wu F, Lu Z, Zeng P, Luo Z, Cao Y, Wen F, Li J, Chen X, Wang F
Therapeutic advances in hematology 2024;15:20406207241301948
Therapeutic advances in hematology 2024;15:20406207241301948
Inhibition of the MyD88 signaling pathway could upregulates Ghrelin expression to synergistically regulate hepatic Echinococcus multilocularis-infected progression.
Zhu J, Zhou T, Chen G, Wu Y, Chen X, Song Y, Tuohetali A, Gao H, Pang D, Wen H, Aimulajiang K
Frontiers in immunology 2024;15:1512180
Frontiers in immunology 2024;15:1512180
Yishen paidu pills attenuates 5/6 nephrectomy induced kidney disease via inhibiting the PI3K/AKT/mTOR signaling pathway.
Liu S, Cao Y, Yuan Q, Xie Y, Zhu Y, Yao L, Zhang C
Frontiers in pharmacology 2024;15:1510098
Frontiers in pharmacology 2024;15:1510098
ATP5J regulates microglial activation via mitochondrial dysfunction, exacerbating neuroinflammation in intracerebral hemorrhage.
Ren N, Zhang H, Li T, Ji H, Zhang Z, Wu H
Frontiers in immunology 2024;15:1509370
Frontiers in immunology 2024;15:1509370
Green carbon dots derived from Zingiberis Rhizoma Carbonisatum alleviate ovalbumin-induced allergic rhinitis.
Zhou L, Yang Y, Li T, Zhao Y, Yuan J, He C, Huang Y, Ma J, Zhang Y, Lu F, Wu J, Li Z, Kong H, Zhao Y, Qu H
Frontiers in immunology 2024;15:1492181
Frontiers in immunology 2024;15:1492181
Shikonin suppresses proliferation of osteosarcoma cells by inducing ferroptosis through promoting Nrf2 ubiquitination and inhibiting the xCT/GPX4 regulatory axis.
Huang R, Chu D, Shi J, Xu R, Wang K
Frontiers in pharmacology 2024;15:1490759
Frontiers in pharmacology 2024;15:1490759
Molecular targets and mechanisms of Sijunzi decoction in the treatment of Parkinson's disease: evidence from network pharmacology, molecular docking, molecular dynamics simulation, and experimental validation.
Jiang Y, Wu W, Xie L, Zhou Y, Yang K, Wu D, Xu W, Fang R, Ge J
Frontiers in pharmacology 2024;15:1487474
Frontiers in pharmacology 2024;15:1487474
MiR-130c-5p targets the SHVV n gene and upregulates immune cytokines (IL-6, IL-22, IL-1β) to inhibit viral replication.
Wei J, Ji Y, Bai Y, Cheng R, Zhang J, Hu X, Zhang C
Frontiers in immunology 2024;15:1486816
Frontiers in immunology 2024;15:1486816
Hyperbaric oxygen-induced acute lung injury: A mouse model study on pathogenic characteristics and recovery dynamics.
Wang S, Chen H, Li Z, Xu G, Bao X
Frontiers in physiology 2024;15:1474933
Frontiers in physiology 2024;15:1474933
KAE ameliorates LPS-mediated acute lung injury by inhibiting PANoptosis through the intracellular DNA-cGAS-STING axis.
Chen Y, Wu X, Jiang Z, Li X
Frontiers in pharmacology 2024;15:1461931
Frontiers in pharmacology 2024;15:1461931
Astrocyte-derived exosomal miR-378a-5p mitigates cerebral ischemic neuroinflammation by modulating NLRP3-mediated pyroptosis.
Sun R, Liao W, Lang T, Qin K, Jiao K, Shao L, Deng C, She Y
Frontiers in immunology 2024;15:1454116
Frontiers in immunology 2024;15:1454116
Comprehensive analysis of lactylation-related gene sets and mitochondrial functions in gastric adenocarcinoma: implications for prognosis and therapeutic strategies.
Yin X, Xing W, Yi N, Zhou Y, Chen Y, Jiang Z, Ma C, Xia C
Frontiers in immunology 2024;15:1451725
Frontiers in immunology 2024;15:1451725
Gasdermin D could be lost in the brain parenchyma infarct core and a pyroptosis-autophagy inhibition effect of Jie-Du-Huo-Xue decoction after stroke.
Zhou C, Qiu SW, Wang FM, Liu YC, Hu W, Yang ML, Liu WH, Li H
Frontiers in pharmacology 2024;15:1449452
Frontiers in pharmacology 2024;15:1449452
RAB42 overexpression correlates with poor prognosis, immune cell infiltration and chemoresistance.
Wang Y, Xie Y, Qian L, Ding R, Pang R, Chen P, Zhang Q, Zhang S
Frontiers in pharmacology 2024;15:1445170
Frontiers in pharmacology 2024;15:1445170
The clinical significance and anti-tumor role of PRKG1 in bladder cancer.
Jin L, Chen T, Sun H, Dai G, Yao Q, Yuan F, Liu X, Xue B
Frontiers in immunology 2024;15:1442555
Frontiers in immunology 2024;15:1442555
YTHDC1 Regulates the Migration, Invasion, Proliferation, and Apoptosis of Rheumatoid Fibroblast-Like Synoviocytes.
Feng ZW, Yang CF, Xiao HF, Yuan F, Chen F, Zhang B, Zhang J, Tan M, Guo MG
Frontiers in immunology 2024;15:1440398
Frontiers in immunology 2024;15:1440398
Integrated bioinformatics analysis of nucleotide metabolism based molecular subtyping and biomarkers in lung adenocarcinoma.
Luo D, Wang H, Zeng Z, Chen J, Wang H
Frontiers in immunology 2024;15:1430171
Frontiers in immunology 2024;15:1430171
Kumujan B suppresses TNF-α-induced inflammatory response and alleviates experimental colitis in mice.
Li X, Di Q, Li X, Zhao X, Wu H, Xiao Y, Tang H, Huang X, Chen J, Chen S, Gao Y, Gao J, Xiao W, Chen W
Frontiers in pharmacology 2024;15:1427340
Frontiers in pharmacology 2024;15:1427340
Identification of potential nucleomodulins of Mycoplasma bovis by direct biotinylation and proximity-based biotinylation approaches.
Lu D, Chen J, Zhang M, Fu Y, Raheem A, Chen Y, Chen X, Hu C, Chen J, Schieck E, Zhao G, Guo A
Frontiers in microbiology 2024;15:1421585
Frontiers in microbiology 2024;15:1421585
A dicoumarol-graphene oxide quantum dot polymer inhibits porcine reproductive and respiratory syndrome virus through the JAK-STAT signaling pathway.
Li Z, Wang J, Wang S, Zhao W, Hou X, Wang J, Dong H, Zhou S, Gao Y, Yao W, Li H, Liu X
Frontiers in microbiology 2024;15:1417404
Frontiers in microbiology 2024;15:1417404
Pulsatilla decoction alleviates DSS-induced UC by activating FXR-ASBT pathways to ameliorate disordered bile acids homeostasis.
Xiao Y, Jia YQ, Liu WJ, Niu C, Mai ZH, Dong JQ, Zhang XS, Yuan ZW, Ji P, Wei YM, Hua YL
Frontiers in pharmacology 2024;15:1399829
Frontiers in pharmacology 2024;15:1399829
Exhausted signature and regulatory network of NK cells in myasthenia gravis.
Zhang Q, Han X, Bi Z, Yang M, Lin J, Li Z, Zhang M, Bu B
Frontiers in immunology 2024;15:1397916
Frontiers in immunology 2024;15:1397916
The mechanism of low molecular weight fucoidan-incorporated nanofiber scaffolds inhibiting oral leukoplakia via SR-A/Wnt signal axis.
Xu M, Sun Y, Cong B, Zhang X, Li Z, Liu Y, Geng L, Qin Q, Wu Y, Gao M, Wang W, Wang Y, Xu Y
Frontiers in pharmacology 2024;15:1397761
Frontiers in pharmacology 2024;15:1397761
Involvement of autophagy in mesaconitine-induced neurotoxicity in HT22 cells revealed through integrated transcriptomic, proteomic, and m6A epitranscriptomic profiling.
Lin X, Zhang J, Wu Z, Shi Y, Chen M, Li M, Hu H, Tian K, Lv X, Li C, Liu Y, Gao X, Yang Q, Chen K, Zhu A
Frontiers in pharmacology 2024;15:1393717
Frontiers in pharmacology 2024;15:1393717
L-arginine combination with 5-fluorouracil inhibit hepatocellular carcinoma cells through suppressing iNOS/NO/AKT-mediated glycolysis.
Hu Y, Xing Y, Fan G, Xie H, Zhao Q, Liu L
Frontiers in pharmacology 2024;15:1391636
Frontiers in pharmacology 2024;15:1391636
FTO diversely influences sensitivity of neuroblastoma cells to various chemotherapeutic drugs.
Lin M, Hua Z, Li Z
Frontiers in pharmacology 2024;15:1384141
Frontiers in pharmacology 2024;15:1384141
Anti-neuroinflammatory effect of hydroxytyrosol: a potential strategy for anti-depressant development.
Li S, Shao H, Sun T, Guo X, Zhang X, Zeng Q, Fang S, Liu X, Wang F, Liu F, Ling P
Frontiers in pharmacology 2024;15:1366683
Frontiers in pharmacology 2024;15:1366683
Lithocarpus polystachyus Rehd. ameliorates cerebral ischemia/reperfusion injury through inhibiting PI3K/AKT/NF-κB pathway and regulating NLRP3-mediated pyroptosis.
Liu D, Wu W, Wang T, Zhan G, Zhang Y, Gao J, Gong Q
Frontiers in pharmacology 2024;15:1365642
Frontiers in pharmacology 2024;15:1365642
Celastrol alleviates diabetic vascular injury via Keap1/Nrf2-mediated anti-inflammation.
An N, Wang R, Li L, Wang B, Wang H, Peng G, Zhou H, Chen G
Frontiers in pharmacology 2024;15:1360177
Frontiers in pharmacology 2024;15:1360177
Alteration in the number, morphology, function, and metabolism of erythrocytes in high-altitude polycythemia.
Yu S, Ye Y, Wuren T, Yi H
Frontiers in physiology 2024;15:1359357
Frontiers in physiology 2024;15:1359357
Dl-3-n-butylphthalide attenuates cerebral ischemia/reperfusion injury in mice through AMPK-mediated mitochondrial fusion.
Zhu T, Dong S, Qin N, Liu R, Shi L, Wan Q
Frontiers in pharmacology 2024;15:1357953
Frontiers in pharmacology 2024;15:1357953
Identification of immune-related endoplasmic reticulum stress genes in proliferative diabetic retinopathy using bioinformatics analysis.
Chen H, Chen E, Liu M, Wang J, Yin J, Zhao P, Xu Y
Frontiers in endocrinology 2024;15:1341206
Frontiers in endocrinology 2024;15:1341206
PCMT1 confirmed as a pan-cancer immune biomarker and a contributor to breast cancer metastasis.
Liu Y, Li H, Shen X, Liu Y, Zhong X, Zhong J, Cao R
American journal of cancer research 2024;14(8):3711-3732
American journal of cancer research 2024;14(8):3711-3732
Evaluation of specific binding of [(11)C]TZ7774 to the receptor-interacting protein kinase 1 (RIPK1) in the brain.
Sakai T, Yamada T, Ikenuma H, Ogata A, Ichise M, Hattori S, Abe J, Tada M, Kakita A, Suzuki M, Ito K, Kato T, Imamura S, Kimura Y
American journal of nuclear medicine and molecular imaging 2024;14(5):345-350
American journal of nuclear medicine and molecular imaging 2024;14(5):345-350
Construction of gastric cancer prognostic signature based on the E26 transcription factor and the identification of novel oncogene ELK3.
Liu C, Zhou L, Chen Z
American journal of cancer research 2024;14(4):1831-1849
American journal of cancer research 2024;14(4):1831-1849
Integrated analysis of lactate-related genes identifies POLRMT as a novel marker promoting the proliferation, migration and energy metabolism of hepatocellular carcinoma via Wnt/β-Catenin signaling.
Wang H, Zhang Y, Du S
American journal of cancer research 2024;14(3):1316-1337
American journal of cancer research 2024;14(3):1316-1337
A multidimensional analysis of ZW10 interacting kinetochore protein in human tumors.
Shu Y, Pang X, Li H, Deng C
American journal of cancer research 2024;14(1):390-402
American journal of cancer research 2024;14(1):390-402
Targeting NANOS1 in triple-negative breast cancer: synergistic effects of digoxin and PD-1 inhibitors in modulating the tumor immune microenvironment.
Wang T, Lei Y, Sun J, Wang L, Lin Y, Wu Z, Zhang S, Cao C, Wang H
Frontiers in oncology 2024;14:1536406
Frontiers in oncology 2024;14:1536406
Identification of key programmed cell death genes for predicting prognosis and treatment sensitivity in colorectal cancer.
Ma JY, Wang YX, Zhao ZY, Xiong ZY, Zhang ZL, Cai J, Guo JW
Frontiers in oncology 2024;14:1483987
Frontiers in oncology 2024;14:1483987
TurboID-mediated proximity labeling technologies to identify virus co-receptors.
Wang B, Yang F, Wang W, Zhao F, Sun X
Frontiers in cellular and infection microbiology 2024;14:1371837
Frontiers in cellular and infection microbiology 2024;14:1371837
Identification and validation of three diagnostic autophagy-related genes associated with advanced plaques and immune cell infiltration in carotid atherosclerosis based on integrated bioinformatics analyses.
Huang T, Su C, Su Q, Nie Y, Xiao Z, Tang Y, Wang J, Luo X, Tang Y
PeerJ 2024;12:e18543
PeerJ 2024;12:e18543
Lysyl oxidase-like 1 predicts the prognosis of patients with primary glioblastoma and promotes tumor invasion via EMT pathway.
Yuan GQ, Zhang G, Nie Q, Wang Z, Gao HZ, Jin GS, Zheng ZQ
PeerJ 2024;12:e17579
PeerJ 2024;12:e17579
Molecular dynamics of chemotactic signalling orchestrates dental pulp stem cell fibrosis during aging.
Sun T, Zhong Q, Yu X, Luo H, Ren F, Liu C, Chen P, Flores-Borja F, Sun H, An Z
Frontiers in cell and developmental biology 2024;12:1530644
Frontiers in cell and developmental biology 2024;12:1530644
Formononetin promotes porcine oocytes maturation and improves embryonic development by reducing oxidative stress.
Wang N, Yang H, Chen Y, Wang H, Wang C, Fan J, Chen Y, Li Y, Zhu M
Frontiers in cell and developmental biology 2024;12:1520429
Frontiers in cell and developmental biology 2024;12:1520429
Antibacterial and antioxidant phlorizin-loaded nanofiber film effectively promotes the healing of burn wounds.
Yang Y, Ma S, Li A, Xia G, Li M, Ding C, Sun X, Yan L, Yang M, Zhao T
Frontiers in bioengineering and biotechnology 2024;12:1428988
Frontiers in bioengineering and biotechnology 2024;12:1428988
PRNP is a pan-cancer prognostic and immunity-related to EMT in colorectal cancer.
Chen H, Du Y, Kong Z, Liao X, Li W
Frontiers in cell and developmental biology 2024;12:1391873
Frontiers in cell and developmental biology 2024;12:1391873
PCSK9 inhibitor alleviates experimental pulmonary fibrosis-induced pulmonary hypertension via attenuating epithelial-mesenchymal transition by suppressing Wnt/β-catenin signaling in vivo and in vitro.
Lin J, Pan Z, Sun J, Wang X, Yin D, Huo C, Guo Q
Frontiers in medicine 2024;11:1509168
Frontiers in medicine 2024;11:1509168
High-fat diet mouse model receiving L-glucose supplementations propagates liver injury.
Amer J, Amleh A, Salhab A, Kolodny Y, Yochelis S, Saffouri B, Paltiel Y, Safadi R
Frontiers in nutrition 2024;11:1469952
Frontiers in nutrition 2024;11:1469952
Resveratrol promotes cholesterol efflux from dendritic cells and controls costimulation and T-cell activation in high-fat and lipopolysaccharide-driven atherosclerotic mice.
Zhang L, Wang H, Wang Z, Xu J, Wang M, Wang W, He Q, Yu Y, Yuan D, Bu G, Qiu R, Long J
Frontiers in cardiovascular medicine 2024;11:1450898
Frontiers in cardiovascular medicine 2024;11:1450898
Supplementation of Ampelopsis grossedentata extract contributes to the improvement of intestinal health in swine.
Liu X, Zhang F, Li M, Li R, Zhang Z, Xu J, Wen L, Li R
Frontiers in veterinary science 2024;11:1417309
Frontiers in veterinary science 2024;11:1417309
Do extracellular vesicles have specific target cells?; Extracellular vesicle mediated embryo maternal communication.
Dissanayake K, Godakumara K, Muhandiram S, Kodithuwakku S, Fazeli A
Frontiers in molecular biosciences 2024;11:1415909
Frontiers in molecular biosciences 2024;11:1415909
Clcn3 deficiency ameliorates high-fat diet-induced obesity and improves metabolism in mice.
Duan S, Li B, Cui S, Chen Y, He Y, Fan L
Frontiers in nutrition 2024;11:1387806
Frontiers in nutrition 2024;11:1387806
Stauntonia chinensis injection relieves neuropathic pain by increasing the expression of PSD-95 and reducing the proliferation of phagocytic microglia.
Deng W, Zou H, Qian L, de Souza SC, Chen Q, Cao S
Ibrain 2024 Spring;10(1):3-18
Ibrain 2024 Spring;10(1):3-18
Expression Characteristics, Immune Signature, and Prognostic Value of the SOCS Family Identified by Multiomics Integrative Analysis in Liver Cancer.
Dong Z, Dai B, Wu R, Fang K, Sui C, Geng L, Yang J
Cancer reports (Hoboken, N.J.) 2024 Sep;7(9):e2161
Cancer reports (Hoboken, N.J.) 2024 Sep;7(9):e2161
The mechanical regulatory role of ATP13a3 in osteogenic differentiation of pre-osteoblasts.
Cao Z, Zhu Y, Li Y, Yuan Z, Han B, Guo Y
Advances in medical sciences 2024 Sep;69(2):339-348
Advances in medical sciences 2024 Sep;69(2):339-348
ASIC1/RIP1 accelerates atherosclerosis via disrupting lipophagy.
Wang YM, Tang H, Tang YJ, Liu J, Yin YF, Tang YL, Feng YG, Gu HF
Journal of advanced research 2024 Sep;63:195-206
Journal of advanced research 2024 Sep;63:195-206
Study on the mechanisms of defective spermatogenesis induced by TiO(2) NPs based on 3D blood-testis barrier microfluidic chip.
Dong R, Li L, Chang H, Song G, Liu S
Toxicology 2024 Sep;507:153888
Toxicology 2024 Sep;507:153888
Intervention of Asprosin Attenuates Oxidative Stress and Neointima Formation in Vascular Injury.
Zheng F, Ye C, Lei JZ, Ge R, Li N, Bo JH, Chen AD, Zhang F, Zhou H, Wang JJ, Chen Q, Li YH, Zhu GQ, Han Y
Antioxidants & redox signaling 2024 Sep;41(7-9):488-504
Antioxidants & redox signaling 2024 Sep;41(7-9):488-504
PFKP is upregulated in 5-fluorouracil-resistant patients and suppresses the antitumor activity of 5-fluorouracil in colorectal cancer in vitro and in vivo.
Deng L, Zhao Y, Liu W
Journal of chemotherapy (Florence, Italy) 2024 Sep;36(5):422-434
Journal of chemotherapy (Florence, Italy) 2024 Sep;36(5):422-434
Shikonin and chitosan-silver nanoparticles synergize against triple-negative breast cancer through RIPK3-triggered necroptotic immunogenic cell death.
Liang J, Tian X, Zhou M, Yan F, Fan J, Qin Y, Chen B, Huo X, Yu Z, Tian Y, Deng S, Peng Y, Wang Y, Liu B, Ma X
Biomaterials 2024 Sep;309:122608
Biomaterials 2024 Sep;309:122608
HSPB8 attenuates lipopolysaccharide‑mediated acute lung injury in A549 cells by activating mitophagy.
Zhou X, Wang M, Sun M, Yao N
Molecular medicine reports 2024 Sep;30(3)
Molecular medicine reports 2024 Sep;30(3)
Netrin‑4 promotes VE‑cadherin expression in endothelial cells through the NF‑κB signaling pathway.
Zhang D, Zhu Z, Wen K, Zhang S, Liu J
Experimental and therapeutic medicine 2024 Sep;28(3):351
Experimental and therapeutic medicine 2024 Sep;28(3):351
UBE2C regulates the KEAP1/NRF2 signaling pathway to promote the growth of gastric cancer by inhibiting autophagy.
Jiang Y, Liu B, Fu L, Li F
International journal of biological macromolecules 2024 Sep;276(Pt 2):134011
International journal of biological macromolecules 2024 Sep;276(Pt 2):134011
Fucoidan alleviates doxorubicin-induced cardiotoxicity by inhibiting ferroptosis via Nrf2/GPX4 pathway.
Wang Y, Han J, Zhan S, Guo C, Yin S, Zhan L, Zhou Q, Liu R, Yan H, Wang X, Yan D
International journal of biological macromolecules 2024 Sep;276(Pt 1):133792
International journal of biological macromolecules 2024 Sep;276(Pt 1):133792
A proton channel, Otopetrin 1 (OTOP1) is N-glycosylated at two asparagine residues in third extracellular loop.
Sasaki O, Yano-Nashimoto S, Yamaguchi S
Journal of cellular physiology 2024 Sep;239(9):e31403
Journal of cellular physiology 2024 Sep;239(9):e31403
STING1-accelerated vascular smooth muscle cell senescence-associated vascular calcification in diabetes is ameliorated by oleoylethanolamide via improved mitochondrial DNA oxidative damage.
Chen Z, Li X, Sun X, Xiao S, Chen T, Ren L, Liu N
Free radical biology & medicine 2024 Sep;222:437-455
Free radical biology & medicine 2024 Sep;222:437-455
A new insight into the mechanism of dichlorodiphenyltrichloroethane-induced hepatotoxicity based on GSDME-mediated pyroptosis.
Tan J, Zhang C, Bao Z, Zhao H, Zhang L, Xu H
Pesticide biochemistry and physiology 2024 Sep;204:106030
Pesticide biochemistry and physiology 2024 Sep;204:106030
Lactobacillus gasseri ATCC33323 affects the intestinal mucosal barrier to ameliorate DSS-induced colitis through the NR1I3-mediated regulation of E-cadherin.
Qian G, Zang H, Tang J, Zhang H, Yu J, Jia H, Zhang X, Zhou J
PLoS pathogens 2024 Sep;20(9):e1012541
PLoS pathogens 2024 Sep;20(9):e1012541
Identification of inflammatory response-related molecular mechanisms based on the ATM/ATR/p53 pathway in tumor cells.
Li C, Chen H, Chen X, Wang P, Shi Y, Xie X, Chen Y, Cai X
Computers in biology and medicine 2024 Sep;180:108776
Computers in biology and medicine 2024 Sep;180:108776
Cinnamaldehyde protects SH-SY5Y cells against advanced glycation end-products induced ectopic cell cycle re-entry.
Wu Y, Zhong J, Wang J, Li H, Chen X, Xia X, Zhou J
Journal of pharmacological sciences 2024 Sep;156(1):1-8
Journal of pharmacological sciences 2024 Sep;156(1):1-8
Nasal solitary chemosensory cells govern daily rhythm in mouse model of allergic rhinitis.
Xu H, Guo L, Hao T, Guo X, Huang M, Cen H, Chen M, Weng J, Huang M, Wu Z, Qin Z, Yang J, Wu B
The Journal of allergy and clinical immunology 2024 Sep;154(3):707-718
The Journal of allergy and clinical immunology 2024 Sep;154(3):707-718
Repression of BRD4 mitigates NLRP3 inflammasome-mediated pyroptosis in Mycobacterium-infected macrophages by repressing endoplasmic reticulum stress.
Wang QY, Yu XF, Ji WL
Tuberculosis (Edinburgh, Scotland) 2024 Sep;148:102542
Tuberculosis (Edinburgh, Scotland) 2024 Sep;148:102542
Involucrasin B suppresses airway inflammation in obese asthma by inhibiting the TLR4-NF-κB-NLRP3 pathway.
Yang Z, Li X, Wei L, Bao L, Hu H, Liu L, Tan W, Tong X, Huang F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155850
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155850
The role of α7nAchR and PD-L1 in neuroimmune regulation of keloid treatment.
Luo Z, Zheng S, Liu J, Qi F
Cellular signalling 2024 Sep;121:111275
Cellular signalling 2024 Sep;121:111275
HDAC8 Enhances the Function of HIF-2α by Deacetylating ETS1 to Decrease the Sensitivity of TKIs in ccRCC.
Qian K, Li W, Ren S, Peng W, Qing B, Liu X, Wei X, Zhu L, Wang Y, Jin X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(36):e2401142
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(36):e2401142
The interlacing anticancer effect of pharmacologic ascorbate, chloroquine, and resveratrol.
Makk-Merczel K, Varga D, Hajdinák P, Szarka A
BioFactors (Oxford, England) 2024 Sep-Oct;50(5):980-996
BioFactors (Oxford, England) 2024 Sep-Oct;50(5):980-996
Exosomes derived from mesenchymal stem cells ameliorate impaired glucose metabolism in myocardial Ischemia/reperfusion injury through miR-132-3p/PTEN/AKT pathway.
Wu H, Hui Y, Qian X, Wang X, Xu J, Wang F, Pan S, Chen K, Liu Z, Gao W, Bai J, Liang G
Cell cycle (Georgetown, Tex.) 2024 Sep-Oct;23(17-20):893-912
Cell cycle (Georgetown, Tex.) 2024 Sep-Oct;23(17-20):893-912
miR-155 induces sepsis-associated damage to the intestinal mucosal barrier via sirtuin 1/nuclear factor-κB-mediated intestinal pyroptosis.
Li Z, Wang Y, Huang W, Shi X, Ma T, Yu X
Acta biochimica et biophysica Sinica 2024 Sep 9;56(11):1618-1632
Acta biochimica et biophysica Sinica 2024 Sep 9;56(11):1618-1632
Rab8a/SNARE complex activation promotes vesicle anchoring and transport in spinal astrocytes to drive neuropathic pain.
Xiao Y, Wang G, He G, Qin W, Shi Y
Biomolecules & biomedicine 2024 Sep 6;24(5):1290-1300
Biomolecules & biomedicine 2024 Sep 6;24(5):1290-1300
Mechanistic investigation of wogonin in delaying the progression of endothelial mesenchymal transition by targeting the TGF-β1 pathway in pulmonary hypertension.
Wang X, Cui L, Wang Y, Zeng Z, Wang H, Tian L, Guo J, Chen Y
European journal of pharmacology 2024 Sep 5;978:176786
European journal of pharmacology 2024 Sep 5;978:176786
Forskolin is an effective therapeutic small molecule for the treatment of hypertrophic cardiomyopathy through ADCY6/cAMP/PKA pathway.
Wang W, Xue Y, Li D, Shao C, Wu K, Sun N, Chen Q
European journal of pharmacology 2024 Sep 5;978:176770
European journal of pharmacology 2024 Sep 5;978:176770
Fluoride induces immunotoxicity by regulating riboflavin transport and metabolism partly through IL-17A in the spleen.
Qiao Y, Cui Y, Tan Y, Zhuang C, Li X, Yong Y, Zhang X, Ren X, Cai M, Yang J, Lang Y, Wang J, Liang C, Zhang J
Journal of hazardous materials 2024 Sep 5;476:135085
Journal of hazardous materials 2024 Sep 5;476:135085
Sortilin-mediated translocation of mitochondrial ACSL1 impairs adipocyte thermogenesis and energy expenditure in male mice.
Yang M, Ge J, Liu YL, Wang HY, Wang ZH, Li DP, He R, Xie YY, Deng HY, Peng XM, Wang WS, Liu JD, Zhu ZZ, Yu XF, Maretich P, Kajimura S, Pan RP, Chen Y
Nature communications 2024 Sep 5;15(1):7746
Nature communications 2024 Sep 5;15(1):7746
Vitamin D receptor alleviates lipid peroxidation in diabetic nephropathy by regulating ACLY/Nrf2/Keap1 pathway.
Zhou Y, Liao Q, Li D, Chen L, Zhang H, Yi B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Sep 30;38(18):e70060
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Sep 30;38(18):e70060
LncRNA PVT1 induces mitochondrial dysfunction of podocytes via TRIM56 in diabetic kidney disease.
Lv Z, Wang Z, Hu J, Su H, Liu B, Lang Y, Yu Q, Liu Y, Fan X, Yang M, Shen N, Zhang D, Zhang X, Wang R
Cell death & disease 2024 Sep 30;15(9):697
Cell death & disease 2024 Sep 30;15(9):697
Targeting G6PD to mitigate cartilage inflammation in TMJOA: The NOX4-ROS-MAPK axis as a therapeutic avenue.
Lin H, He K, Zhang S, Chen H, Wang C, Lu J, Ou Y, Chen W, Zhou Y, Li Y, Chen J
International immunopharmacology 2024 Sep 30;139:112688
International immunopharmacology 2024 Sep 30;139:112688
Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation.
Zhou J, Zhang L, Peng J, Zhang X, Zhang F, Wu Y, Huang A, Du F, Liao Y, He Y, Xie Y, Gu L, Kuang C, Ou W, Xie M, Tu T, Pang J, Zhang D, Guo K, Feng Y, Yin S, Cao Y, Li T, Jiang Y
Cell metabolism 2024 Sep 3;36(9):2054-2068.e14
Cell metabolism 2024 Sep 3;36(9):2054-2068.e14
SOST/Sclerostin impairs the osteogenesis and angiogesis in glucocorticoid-associated osteonecrosis of femoral head.
Huang J, Ma T, Wang C, Wang Z, Wang X, Hua B, Jiang C, Yan Z
Molecular medicine (Cambridge, Mass.) 2024 Sep 28;30(1):167
Molecular medicine (Cambridge, Mass.) 2024 Sep 28;30(1):167
Diminished expression of the ubiquitin-proteasome system in early treatment-naïve patients with rheumatoid arthritis and concomitant type 2 diabetes may be linked to IL-1 pathway hyper-activity; results from PEAC cohort.
Ruscitti P, Currado D, Rivellese F, Vomero M, Navarini L, Cipriani P, Pitzalis C, Giacomelli R
Arthritis research & therapy 2024 Sep 28;26(1):171
Arthritis research & therapy 2024 Sep 28;26(1):171
Role of β-adrenergic signaling and the NLRP3 inflammasome in chronic intermittent hypoxia-induced murine lung cancer progression.
Sun J, Jia X, Zhang Z, Yang Y, Zhai C, Zhao B, Liu Y
Respiratory research 2024 Sep 28;25(1):347
Respiratory research 2024 Sep 28;25(1):347
Exercise training upregulates CD55 to suppress complement-mediated synaptic phagocytosis in Parkinson's disease.
Yao H, Tong W, Song Y, Li R, Xiang X, Cheng W, Zhou Y, He Y, Yang Y, Liu Y, Li S, Jin L
Journal of neuroinflammation 2024 Sep 28;21(1):246
Journal of neuroinflammation 2024 Sep 28;21(1):246
Adaptive Differences in Cellular and Behavioral Responses to Circadian Disruption between C57BL/6 and BALB/c Strains.
Ma C, Li H, Li W, Yang G, Chen L
International journal of molecular sciences 2024 Sep 27;25(19)
International journal of molecular sciences 2024 Sep 27;25(19)
LncRNA lncLLM Facilitates Lipid Deposition by Promoting the Ubiquitination of MYH9 in Chicken LMH Cells.
Jia QH, Cao YZ, Xing YX, Guan HB, Ma CL, Li X, Tian WH, Li ZJ, Tian YD, Li GX, Jiang RR, Kang XT, Liu XJ, Li H
International journal of molecular sciences 2024 Sep 25;25(19)
International journal of molecular sciences 2024 Sep 25;25(19)
Single-cell dissection of the human blood-brain barrier and glioma blood-tumor barrier.
Xie Y, Yang F, He L, Huang H, Chao M, Cao H, Hu Y, Fan Z, Zhai Y, Zhao W, Liu X, Zhao R, Xiao B, Shi X, Luo Y, Yin J, Feng D, Hugnot JP, Muhl L, Dimberg A, Betsholtz C, Zhang Y, Wang L, Zhang L
Neuron 2024 Sep 25;112(18):3089-3105.e7
Neuron 2024 Sep 25;112(18):3089-3105.e7
Rice Husk Silica Liquid Enhances Autophagy and Reduces Overactive Immune Responses via TLR-7 Signaling in Lupus-Prone Models.
Kao C, Wang SW, Chen PC, Huang CY, Wei YF, Ho CH, Hong YH
International journal of molecular sciences 2024 Sep 21;25(18)
International journal of molecular sciences 2024 Sep 21;25(18)
CircPOLA2 sensitizes non-small cell lung cancer cells to ferroptosis and suppresses tumorigenesis via the Merlin-YAP signaling pathway.
Xu K, Wei G, Qi W, Ye C, Liu Y, Wang S, Yang F, Tang J
iScience 2024 Sep 20;27(9):110832
iScience 2024 Sep 20;27(9):110832
Mesenchymal stem cells in tumor microenvironment: drivers of bladder cancer progression through mitochondrial dynamics and energy production.
Yang E, Jing S, Wang F, Wang H, Fu S, Yang L, Tian J, Golijanin DJ, El-Deiry WS, Cheng L, Wang Z
Cell death & disease 2024 Sep 20;15(9):688
Cell death & disease 2024 Sep 20;15(9):688
Duck hepatitis A virus utilizes PCBP2 to facilitate viral translation and replication.
Xu C, Jiang Y, Wang M, Cheng A, Zhang W, Ou X, Sun D, Yang Q, Wu Y, Tian B, He Y, Wu Z, Zhang S, Zhao X, Huang J, Zhu D, Chen S, Liu M, Jia R
Veterinary research 2024 Sep 19;55(1):110
Veterinary research 2024 Sep 19;55(1):110
Mandarin fish von Hippel-Lindau protein regulates the NF-κB signaling pathway via interaction with IκB to promote fish ranavirus replication.
Li ZM, Qin XW, Zhang Q, He J, Liang MC, Li CR, Yu Y, Liu WH, Weng SP, He JG, Guo CJ
Zoological research 2024 Sep 18;45(5):990-1000
Zoological research 2024 Sep 18;45(5):990-1000
Palliative effect of rotating magnetic field on glucocorticoid-induced osteonecrosis of the femoral head in rats by regulating osteoblast differentiation.
Yang H, Nie S, Zhou C, Li M, Yu Q, Mo Y, Wei Y, Wang X
Biochemical and biophysical research communications 2024 Sep 17;725:150265
Biochemical and biophysical research communications 2024 Sep 17;725:150265
Glucose attenuates the long-term adverse neurodevelopment effect of neonate pain stimulus via CRF/GR in rats.
Xu J, Jie J, Feng C, Sun Q, Fan J, Li D
Biochemical and biophysical research communications 2024 Sep 17;725:150219
Biochemical and biophysical research communications 2024 Sep 17;725:150219
HSV-1 immune escapes in microglia by down-regulating GM130 to inhibit TLR3-mediated innate immune responses.
Liu J, Chen X, Liu J, Zhang H, Lu W
Virology journal 2024 Sep 16;21(1):219
Virology journal 2024 Sep 16;21(1):219
Inhibiting Soluble Epoxide Hydrolase Suppresses NF-κB p65 Signaling and Reduces CXCL10 Expression as a Potential Therapeutic Target in Hashimoto's Thyroiditis.
Feng J, Xu X, Cai W, Yang X, Niu R, Han Z, Tian L
The Journal of clinical endocrinology and metabolism 2024 Sep 16;109(10):2579-2588
The Journal of clinical endocrinology and metabolism 2024 Sep 16;109(10):2579-2588
Exosome miRNA profile and mitigating effect of miR-23a-3p/Cul3 axis on apoptosis in the pathogenesis of SiO(2) dust-induced lung fibrosis.
Chang S, Xie W, Qu H, Ban J, Ma P, Fei S, Liu F
Ecotoxicology and environmental safety 2024 Sep 15;283:116971
Ecotoxicology and environmental safety 2024 Sep 15;283:116971
Mitigating lead-induced osteoporosis: The role of butyrate in gut-bone axis restoration.
Ge Y, Jia Z, Zhao S, Zhang W, Shi X, Xie R, Gong Y, Sheng J, van 't Hof RJ, Yang J, Han C, Hu X, Wang Y, Wu Y, Li C, Wang M
Ecotoxicology and environmental safety 2024 Sep 15;283:116943
Ecotoxicology and environmental safety 2024 Sep 15;283:116943
Integrating metagenomics with metabolomics for gut microbiota and metabolites profiling in acute pancreatitis.
Jia Y, Shi Y, Wang J, Liu H, Huang Y, Wang H, Liu Y, Peng J
Scientific reports 2024 Sep 14;14(1):21491
Scientific reports 2024 Sep 14;14(1):21491
DMDD, isolated from Averrhoa carambola L., ameliorates diabetic nephropathy by regulating endoplasmic reticulum stress-autophagy crosstalk.
Shi J, Wang Y, Liang T, Wang X, Xie J, Huang R, Xu X, Wei X
Chinese medicine 2024 Sep 12;19(1):125
Chinese medicine 2024 Sep 12;19(1):125
Alkaloids of Aconiti Lateralis Radix Praeparata inhibit growth of non-small cell lung cancer by regulating PI3K/Akt-mTOR signaling and glycolysis.
Zhang W, Cai S, Qin L, Feng Y, Ding M, Luo Z, Shan J, Di L
Communications biology 2024 Sep 11;7(1):1118
Communications biology 2024 Sep 11;7(1):1118
Kidney targeting and modulating macrophage polarization through AMPK signaling: Therapeutic mechanism of berberine in uric acid nephropathy.
Gong S, Chen J, Zheng X, Lu X, Chen M, Li J, Su Z, Liu Y, Chen J, Xie J, Xie Q, Li Y
International immunopharmacology 2024 Sep 10;138:112632
International immunopharmacology 2024 Sep 10;138:112632
Alleviation effects of dexmedetomidine on myocardial ischemia/reperfusion injury through fatty acid metabolism pathway via Elovl6.
Yuan H, Guo J, Wang C, Zhang C
International immunopharmacology 2024 Sep 10;138:112588
International immunopharmacology 2024 Sep 10;138:112588
Neuronal ferroptosis and ferroptosis-mediated endoplasmic reticulum stress: Implications in cognitive dysfunction induced by chronic intermittent hypoxia in mice.
Zhong P, Li L, Feng X, Teng C, Cai W, Zheng W, Wei J, Li X, He Y, Chen B, An X, Cai X
International immunopharmacology 2024 Sep 10;138:112579
International immunopharmacology 2024 Sep 10;138:112579
β-Caryophyllene mitigates ischemic stroke-induced white matter lesions by inhibiting pyroptosis.
Xin Q, Xu F, Ma Z, Wu J
Experimental cell research 2024 Sep 1;442(1):114214
Experimental cell research 2024 Sep 1;442(1):114214
Glucose influences endometrial receptivity to embryo implantation through O-GlcNAcylation-mediated regulation of the cytoskeleton.
Ruane PT, Paterson I, Reeves B, Adlam D, Berneau SC, Renshall L, Brosens JJ, Kimber SJ, Brison DR, Aplin JD, Westwood M
American journal of physiology. Cell physiology 2024 Sep 1;327(3):C634-C645
American journal of physiology. Cell physiology 2024 Sep 1;327(3):C634-C645
LRP1 facilitates hepatic glycogenesis by improving the insulin signaling pathway in HFD-fed mice.
Guo X, Pu J, Tang Z, Jia C, Yang F, Liu T, Ding Y
Animal models and experimental medicine 2024 Oct;7(5):696-706
Animal models and experimental medicine 2024 Oct;7(5):696-706
Promotion of DNA end resection by BRCA1-BARD1 in homologous recombination.
Salunkhe S, Daley JM, Kaur H, Tomimatsu N, Xue C, Raina VB, Jasper AM, Rogers CM, Li W, Zhou S, Mojidra R, Kwon Y, Fang Q, Ji JH, Badamchi Shabestari A, Fitzgerald O, Dinh H, Mukherjee B, Habib AA, Hromas R, Mazin AV, Wasmuth EV, Olsen SK, Libich DS, Zhou D, Zhao W, Greene EC, Burma S, Sung P
Nature 2024 Oct;634(8033):482-491
Nature 2024 Oct;634(8033):482-491
Angelica sinensis polysaccharides promote extramedullary stress erythropoiesis via ameliorating splenic glycolysis and EPO/STAT5 signaling-regulated macrophages.
Sun N, Wang Z, Jiang H, Wang B, Du K, Huang C, Wang C, Yang T, Wang Y, Liu Y, Wang L
Journal of molecular histology 2024 Oct;55(5):661-673
Journal of molecular histology 2024 Oct;55(5):661-673
Mechanism of Treadmill Exercise Combined with Rich Environmental Stimulation to Improve Depression in Post-stroke Depression Model Rats.
Lu L, Xu W, Feng L, Teng X, Ban W, Xue Y, Xing X, Zeng W, Li B
Actas espanolas de psiquiatria 2024 Oct;52(5):693-704
Actas espanolas de psiquiatria 2024 Oct;52(5):693-704
Ellagic acid improves osteoarthritis by inhibiting PGE2 production in M1 macrophages via targeting PTGS2.
Zhang C, Li X, Wen P, Li Y
Clinical and experimental pharmacology & physiology 2024 Oct;51(10):e13918
Clinical and experimental pharmacology & physiology 2024 Oct;51(10):e13918
Golgi protein ACBD3 downregulation sensitizes cells to ferroptosis.
Qian Y, Ma S, Qiu R, Sun Z, Liu W, Wu F, Lam SM, Xia Z, Wang K, Fang L, Shui G, Cao X
Cell biology international 2024 Oct;48(10):1559-1572
Cell biology international 2024 Oct;48(10):1559-1572
Groenlandicine enhances cisplatin sensitivity in cisplatin-resistant osteosarcoma cells through the BAX/Bcl-2/Caspase-9/Caspase-3 pathway.
Zhao Z, Wu Q, Xu Y, Qin Y, Pan R, Meng Q, Li S
Journal of bone oncology 2024 Oct;48:100631
Journal of bone oncology 2024 Oct;48:100631
Quercetin Regulates Microglia M1/M2 Polarization and Alleviates Retinal Inflammation via ERK/STAT3 Pathway.
Zou Y, Jiang J, Li Y, Ding X, Fang F, Chen L
Inflammation 2024 Oct;47(5):1616-1633
Inflammation 2024 Oct;47(5):1616-1633
A novel small-molecule PCSK9 inhibitor E28362 ameliorates hyperlipidemia and atherosclerosis.
Wang WZ, Liu C, Luo JQ, Lei LJ, Chen MH, Zhang YY, Sheng R, Li YN, Wang L, Jiang XH, Xiao TM, Zhang YH, Li SW, Wu YX, Xu Y, Xu YN, Si SY
Acta pharmacologica Sinica 2024 Oct;45(10):2119-2133
Acta pharmacologica Sinica 2024 Oct;45(10):2119-2133
GFPT2 expression is induced by gemcitabine administration and enhances invasion by activating the hexosamine biosynthetic pathway in pancreatic cancer.
Miyazaki K, Ariake K, Sato S, Miura T, Xun J, Douchi D, Ishida M, Ohtsuka H, Mizuma M, Nakagawa K, Kamei T, Unno M
Clinical & experimental metastasis 2024 Oct;41(5):777-789
Clinical & experimental metastasis 2024 Oct;41(5):777-789
ADSC-derived exosomes provide neuroprotection in sepsis-associated encephalopathy by regulating hippocampal pyroptosis.
Zhan Y, Zhang L, Sun J, Yao H, Chen J, Tian M
Experimental neurology 2024 Oct;380:114900
Experimental neurology 2024 Oct;380:114900
USP14 promotes the cancer stem-like cell properties of OSCC via promoting SOX2 deubiquitination.
Liu C, Zhou S, Tang W
Oral diseases 2024 Oct;30(7):4255-4265
Oral diseases 2024 Oct;30(7):4255-4265
Duck plague virus-encoded microRNA dev-miR-D28-3p inhibits viral replication via targeting UL27.
Ni H, Zhang X, Huang J, Wang M, Cheng A, Liu M, Zhu D, Chen S, Zhao X, Yang Q, Wu Y, Zhang S, Ou X, Sun D, Tian B, Jing B, Jia R
Veterinary microbiology 2024 Oct;297:110202
Veterinary microbiology 2024 Oct;297:110202
Emodin induces ferroptosis in colorectal cancer through NCOA4-mediated ferritinophagy and NF-κb pathway inactivation.
Shen Z, Zhao L, Yoo SA, Lin Z, Zhang Y, Yang W, Piao J
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1810-1823
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1810-1823
Vitamin D inhibits ferroptosis and mitigates the kidney injury of prediabetic mice by activating the Klotho/p53 signaling pathway.
Chen H, Zhang Y, Miao Y, Song H, Tang L, Liu W, Li W, Miao J, Li X
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1780-1792
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1780-1792
Validation of quercetin in the treatment of colon cancer with diabetes via network pharmacology, molecular dynamics simulations, and in vitro experiments.
Zhou W, Cao W, Wang M, Yang K, Zhang X, Liu Y, Zhang P, Zhang Z, Cao G, Chen B, Xiong M
Molecular diversity 2024 Oct;28(5):2947-2965
Molecular diversity 2024 Oct;28(5):2947-2965
Dihydroartemisinin inhibits ATP6 activity, reduces energy metabolism of hepatocellular carcinoma cells, promotes apoptosis and inhibits metastasis via CANX.
Chang J, Yang Q, Liu X, Li W, Gao L
Oncology letters 2024 Oct;28(4):474
Oncology letters 2024 Oct;28(4):474
Mitogen-activated protein kinase kinase kinase 1 facilitates the temozolomide resistance and migration of GBM via the MEK/ERK signalling.
Wu S, Xue S, Tang Y, Zhao W, Zheng M, Cheng Z, Hu X, Sun J, Ren J
Journal of cellular and molecular medicine 2024 Oct;28(20):e70173
Journal of cellular and molecular medicine 2024 Oct;28(20):e70173
Small nucleolar RNA host gene 5 plays a role in orthodontic tooth movement by inhibiting osteoclast differentiation.
Feng J, Tan A, Li W, Zheng Y
Orthodontics & craniofacial research 2024 Oct;27(5):775-784
Orthodontics & craniofacial research 2024 Oct;27(5):775-784
Identification and Verification of Key Genes Associated with Temozolomide Resistance in Glioblastoma Based on Comprehensive Bioinformatics Analysis.
Hu J, Yang J, Hu N, Shi Z, Hu T, Mi B, Wang H, Chen W
Iranian journal of biotechnology 2024 Oct;22(4):e3892
Iranian journal of biotechnology 2024 Oct;22(4):e3892
Oncoprotein-induced transcript 3 protein-enriched extracellular vesicles promotes NLRP3 ubiquitination to alleviate acute lung injury after cardiac surgery.
Li Y, Chen YT, Liu JS, Liang KF, Song YK, Cao Y, Chen CY, Jian YP, Liu XJ, Xu YQ, Yuan HX, Ou ZJ, Ou JS
Journal of molecular and cellular cardiology 2024 Oct;195:55-67
Journal of molecular and cellular cardiology 2024 Oct;195:55-67
The protective role of quercetin against copper-induced female reproductive toxicity: Insights from transcriptome analysis.
Qi N, Wang B, Xing W, Ge F, Liu J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Oct;192:114934
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Oct;192:114934
Combined effects of TiO(2) nanoparticle and fipronil co-exposure on microbiota in mouse intestine.
Wang C, Liu Y, He Y, Li J, Cao Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Oct;192:114931
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Oct;192:114931
Procyanidine alleviates bisphenol A-induced apoptosis in TM3 cells via the Nrf2 signaling pathway.
Pan F, Yang W, Zhao T, Liu K, Zhao S, Zhao L
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Oct;192:114908
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Oct;192:114908
AMPK induces PIAS3 mediated SUMOylation of E3 ubiquitin ligase Smurf1 impairing osteogenic differentiation and traumatic heterotopic ossification.
Chen J, Dang YM, Liu MC, Gao L, Guan T, Hu A, Xiong L, Lin H
Biochimica et biophysica acta. Molecular cell research 2024 Oct;1871(7):119771
Biochimica et biophysica acta. Molecular cell research 2024 Oct;1871(7):119771
EREG silencing inhibits tumorigenesis via inactivating ERK/p38 MAPK pathway in pancreatic ductal adenocarcinoma.
Liu F, Wu W, Cao W, Feng L, Yuan J, Ren Z, Dai N, Wang X, Li X, Yue S
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167336
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167336
HIF-1 induced tiRNA-Lys-CTT-003 is protective against cisplatin induced ferroptosis of renal tubular cells in mouse AKI model.
Li D, Xie X, Zhan Z, Li N, Yin N, Yang S, Liu J, Wang J, Li Z, Yi B, Zhang H, Zhang W
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167277
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167277
Ghrelin is involved in regulating the progression of Echinococcus Granulosus-infected liver lesions through suppression of immunoinflammation and fibrosis.
Zhu J, Zhao H, Aierken A, Zhou T, Menggen M, Gao H, He R, Aimulajiang K, Wen H
PLoS neglected tropical diseases 2024 Oct;18(10):e0012587
PLoS neglected tropical diseases 2024 Oct;18(10):e0012587
Seno-antigen-pulsed dendritic cell vaccine induce anti-aging immunity to improve adipose tissue senescence and metabolic abnormalities.
Cao Y, Du X, Yu J, Wang Y, Jin X, Gu B, Yin Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Oct;179:117433
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Oct;179:117433
Effects of exogenous hydrogen sulfide and honokiol intervention on the proliferation, apoptosis, and calcium signaling pathway of rat enteric glial cells.
Liu P, Zhang X, Zhao N, Dai J, Liang G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Oct;179:117290
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Oct;179:117290
Mechanisms of Shufeng Jiedu Capsule in treating bacterial pneumonia based on network pharmacology and experimental verification.
Xu Y, Bao L, Zhao R, Geng Z, Li S, Pang B, Sun Q, Guo S, Cui X, Sun J
Chinese herbal medicines 2024 Oct;16(4):656-666
Chinese herbal medicines 2024 Oct;16(4):656-666
Xianling Lianxia formula improves the efficacy of trastuzumab by enhancing NK cell-mediated ADCC in HER2-positive BC.
Li F, Shi Y, Ma M, Yang X, Chen X, Xie Y, Liu S
Journal of pharmaceutical analysis 2024 Oct;14(10):100977
Journal of pharmaceutical analysis 2024 Oct;14(10):100977
Jiawei Buzhong Yiqi Decoction attenuates polycystic ovary syndrome through regulating kisspeptin-GPR54-AKT-SHBG system.
Hu R, Geng Y, Huang Y, Liu Z, Li F, Song K, Ma W, Dong H, Zhang M, Lei T, Song Y, Zhang Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Oct;133:155931
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Oct;133:155931
Gastrodin exerts perioperative myocardial protection by improving mitophagy through the PINK1/Parkin pathway to reduce myocardial ischemia-reperfusion injury.
Chen L, Lv Y, Wu H, Wang Y, Xu Z, Liu G, He Y, Li X, Liu J, Feng Y, Bai Y, Xie W, Zhou Q, Wu Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Oct;133:155900
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Oct;133:155900
The MEF2A/SNHG16/miR-425-5p/NOTCH2 axis induces gemcitabine resistance by inhibiting ferroptosis in the starving bladder tumor microenvironment.
Zhou X, Zhang C, Yu H, Feng Z, Bai X, Mei Y, Li L, Li X, Gou X, Deng Y
Cellular signalling 2024 Oct;122:111337
Cellular signalling 2024 Oct;122:111337
Endothelial Cells Mediated by STING Regulate Oligodendrogenesis and Myelination During Brain Development.
Wang W, Wang Y, Su L, Zhang M, Zhang T, Zhao J, Ma H, Zhang D, Ji F, Jiao RD, Li H, Xu Y, Chen L, Jiao J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Oct;11(38):e2308508
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Oct;11(38):e2308508
Single-cell dissection reveals promotive role of ENO1 in leukemia stem cell self-renewal and chemoresistance in acute myeloid leukemia.
Tian Y, Guo J, Mao L, Chen Z, Zhang X, Li Y, Zhang Y, Zha X, Luo OJ
Stem cell research & therapy 2024 Oct 8;15(1):347
Stem cell research & therapy 2024 Oct 8;15(1):347
Aldo-keto reductase family 1 member C3 mediates radioresistance of esophageal cancer cells through suppressing MAPK and AKT signaling.
Xiong W, Xie Y, Wang D, Huang X, Hao X, Liu J, Liu X, Gu X, Sun S, Li Y, Li J
BMC cancer 2024 Oct 7;24(1):1236
BMC cancer 2024 Oct 7;24(1):1236
Characterizations of Protein Arginine Deiminase 1 as a Substrate of NTMT1: Implications of Nα-Methylation in Protein Stability and Interaction.
Meng Y, Li Z, He M, Zhang Q, Deng Y, Wang Y, Huang R
Journal of proteome research 2024 Oct 4;23(10):4589-4600
Journal of proteome research 2024 Oct 4;23(10):4589-4600
Characteristics of Myocardial Structure and Central Carbon Metabolism during the Early and Compensatory Stages of Cardiac Hypertrophy.
Chen Y, Luo YM, Li D, Liu H, Luo X, Zhang X, Ling Y, Ouyang W
Journal of proteome research 2024 Oct 4;23(10):4229-4241
Journal of proteome research 2024 Oct 4;23(10):4229-4241
Advanced paternal age exacerbates neuroinflammation in offspring via m6A modification-mediated intergenerational inheritance.
Mao Y, Meng Y, Zou K, Qin N, Wang Y, Yan J, Chen P, Cheng Y, Shi W, Zhou C, Chen H, Sheng J, Liu X, Pan J, Huang H
Journal of neuroinflammation 2024 Oct 4;21(1):249
Journal of neuroinflammation 2024 Oct 4;21(1):249
PYGL regulation of glycolysis and apoptosis in glioma cells under hypoxic conditions via HIF1α-dependent mechanisms.
Cao T, Wang J
Translational cancer research 2024 Oct 31;13(10):5627-5648
Translational cancer research 2024 Oct 31;13(10):5627-5648
Bioinformatics analysis reveals SOD1 is a prognostic factor in lung adenocarcinoma.
Gao L, Wang W, Ma H, Yin M, Yang X, Han R, Ohara S, Kim D, Wang G
Translational cancer research 2024 Oct 31;13(10):5522-5534
Translational cancer research 2024 Oct 31;13(10):5522-5534
PAIP1 binds to pre-mRNA and regulates alternative splicing of cancer pathway genes including VEGFA.
Zheng J, Zhang X, Xue Y, Shao W, Wei Y, Mi S, Yang X, Hu L, Zhang Y, Liang M
BMC genomics 2024 Oct 3;25(1):926
BMC genomics 2024 Oct 3;25(1):926
Diagnostic and prognostic significance of tetraspanin 6 and its role in facilitating glioma progression.
Sa L, Jiang J, Li Y, Huo Y, Zheng W, Zhang H, Zhang L, Wang T, Shan L
European journal of medical research 2024 Oct 29;29(1):522
European journal of medical research 2024 Oct 29;29(1):522
Rapid increase of MFGE8 secretion from endometrial epithelial cells is an indicator of extracellular vesicle mediated embryo maternal dialogue.
Muhandiram S, Kodithuwakku S, Godakumara K, Fazeli A
Scientific reports 2024 Oct 29;14(1):25911
Scientific reports 2024 Oct 29;14(1):25911
Erjingpill bionic cerebrospinal fluid alleviates LPS-induced inflammatory response in BV2 cells by inhibiting glycolysis via mTOR.
Wang S, Wu L, Xie Y, Ge S, Wu Y, Chen L, Yi L, Yang J, Duan F, Huang L
Journal of ethnopharmacology 2024 Oct 28;333:118412
Journal of ethnopharmacology 2024 Oct 28;333:118412
The pro-tumor activity of INTS7 on lung adenocarcinoma via inhibiting immune infiltration and activating p38MAPK pathway.
Li X, Lu F, Cao M, Yao Y, Guo J, Zeng G, Qian J
Scientific reports 2024 Oct 27;14(1):25636
Scientific reports 2024 Oct 27;14(1):25636
Morin alleviates DSS-induced ulcerative colitis in mice via inhibition of inflammation and modulation of intestinal microbiota.
Qiu L, Yan C, Yang Y, Liu K, Yin Y, Zhang Y, Lei Y, Jia X, Li G
International immunopharmacology 2024 Oct 25;140:112846
International immunopharmacology 2024 Oct 25;140:112846
Virtual Screening, Molecular Dynamics, and Mechanism Study of Homeodomain-Interacting Protein Kinase 2 Inhibitor in Renal Fibroblasts.
Hu X, Wu Y, Ouyang H, Wu J, Yao M, Chen Z, Li Q
Pharmaceuticals (Basel, Switzerland) 2024 Oct 23;17(11)
Pharmaceuticals (Basel, Switzerland) 2024 Oct 23;17(11)
Macrophage NRF1 promotes mitochondrial protein turnover via the ubiquitin proteasome system to limit mitochondrial stress and inflammation.
Yan J, Zhang X, Wang H, Jia X, Wang R, Wu S, Zhu ZJ, Tan M, Horng T
Cell reports 2024 Oct 22;43(10):114780
Cell reports 2024 Oct 22;43(10):114780
Ketone Esters Partially and Selectively Rescue Mitochondrial Bioenergetics After Acute Cervical Spinal Cord Injury in Rats: A Time-Course.
Seira O, Park HD, Liu J, Poovathukaran M, Clarke K, Boushel R, Tetzlaff W
Cells 2024 Oct 22;13(21)
Cells 2024 Oct 22;13(21)
GLP-1R activation attenuates the progression of pulmonary fibrosis via disrupting NLRP3 inflammasome/PFKFB3-driven glycolysis interaction and histone lactylation.
Liu C, Zhang Q, Zhou H, Jin L, Liu C, Yang M, Zhao X, Ding W, Xie W, Kong H
Journal of translational medicine 2024 Oct 21;22(1):954
Journal of translational medicine 2024 Oct 21;22(1):954
Tetramethylpyrazine Analogue T-006 Protects Neuronal and Endothelial Cells Against Oxidative Stress via PI3K/AKT/mTOR and Nrf2 Signaling.
Zhang G, Liang Z, Wang Y, Zhang Z, Hoi PM
Antioxidants (Basel, Switzerland) 2024 Oct 21;13(10)
Antioxidants (Basel, Switzerland) 2024 Oct 21;13(10)
Impact of polystyrene nanoplastics on apoptosis and inflammation in zebrafish larvae: Insights from reactive oxygen species perspective.
Pei J, Chen S, Li L, Wang K, Pang A, Niu M, Peng X, Li N, Wu H, Nie P
The Science of the total environment 2024 Oct 20;948:174737
The Science of the total environment 2024 Oct 20;948:174737
Nasal instillation of polystyrene nanoplastics induce lung injury via mitochondrial DNA release and activation of the cyclic GMP-AMP synthase-stimulator of interferon genes-signaling cascade.
Liu J, Xu F, Guo M, Gao D, Song Y
The Science of the total environment 2024 Oct 20;948:174674
The Science of the total environment 2024 Oct 20;948:174674
Astragaloside I Promotes Lipophagy and Mitochondrial Biogenesis to Improve Hyperlipidemia by Regulating Akt/mTOR/TFEB Pathway.
Zhao J, Gao G, Ding J, Liu W, Wang T, Zhao L, Xu J, Zhang Z, Zhang X, Xie Z
Journal of agricultural and food chemistry 2024 Oct 2;72(39):21548-21559
Journal of agricultural and food chemistry 2024 Oct 2;72(39):21548-21559
Regorafenib promotes antitumor progression in melanoma by reducing RRM2.
Xuan X, Li Y, Huang C, Zhang Y
iScience 2024 Oct 18;27(10):110993
iScience 2024 Oct 18;27(10):110993
MIR194-2HG, a miRNA host gene activated by HNF4A, inhibits gastric cancer by regulating microRNA biogenesis.
Cao H, Wang Z, Guo Q, Qin S, Li D
Biology direct 2024 Oct 18;19(1):95
Biology direct 2024 Oct 18;19(1):95
Neutrophil N1 polarization induced by cardiomyocyte-derived extracellular vesicle miR-9-5p aggravates myocardial ischemia/reperfusion injury.
Zhang Y, Li X, Dai Y, Han Y, Wei X, Wei G, Chen W, Kong S, He Y, Liu H, Ma N, Bin J, Tan N, He P, Liu Y
Journal of nanobiotechnology 2024 Oct 16;22(1):632
Journal of nanobiotechnology 2024 Oct 16;22(1):632
Micro RNA-175 Targets Claudin-1 to Inhibit Madin-Darby Canine Kidney Cell Adhesion.
Li X, Ma F, Wang S, Tang T, Ma L, Qiao Z, Ma Z, Wang J, Liu Z
Genes 2024 Oct 16;15(10)
Genes 2024 Oct 16;15(10)
Overexpression of USP35 enhances the protective effect of hUC-MSCs and their extracellular vesicles in oxygen-glucose deprivation/reperfusion-induced SH-SY5Y cells via stabilizing FUNDC1.
Wang S, Li X, Wang T, Sun Z, Feng E, Jin Y
Communications biology 2024 Oct 15;7(1):1330
Communications biology 2024 Oct 15;7(1):1330
Potential involvement of connective tissue growth factor in chondrocytes apoptosis of Kashin-Beck disease.
Yang X, Liu H, Cheng S, Pan C, Cai Q, Chu X, Shi S, Wei W, He D, Cheng B, Wen Y, Jia Y, Tinkov AA, Skalny AV, Zhang F
Ecotoxicology and environmental safety 2024 Oct 15;285:117148
Ecotoxicology and environmental safety 2024 Oct 15;285:117148
The Application of Duck Embryonic Fibroblasts CCL-141 as a Cell Model for Adipogenesis.
Sun DD, Li XQ, Liu YT, Ge MQ, Hou ZC
Animals : an open access journal from MDPI 2024 Oct 15;14(20)
Animals : an open access journal from MDPI 2024 Oct 15;14(20)
Daucosterol alleviates heart failure with preserved ejection fraction through activating PPARα pathway.
Zhou J, Wang B, Wang M, Zha Y, Lu S, Zhang F, Peng Y, Duan Y, Zhong D, Zhang S
Heliyon 2024 Oct 15;10(19):e38379
Heliyon 2024 Oct 15;10(19):e38379
NF-κB pathway activation by Octopus peptide hydrolysate ameliorates gut dysbiosis and enhances immune response in cyclophosphamide-induced mice.
Ali M, Ullah H, Farooqui NA, Deng T, Siddiqui NZ, Ilyas M, Ali S, Rahman MU, Rehman AU, Alioui Y, Wang L, Yi X
Heliyon 2024 Oct 15;10(19):e38370
Heliyon 2024 Oct 15;10(19):e38370
zMAP toolset: model-based analysis of large-scale proteomic data via a variance stabilizing z-transformation.
Gui X, Huang J, Ruan L, Wu Y, Guo X, Cao R, Zhou S, Tan F, Zhu H, Li M, Zhang G, Zhou H, Zhan L, Liu X, Tu S, Shao Z
Genome biology 2024 Oct 14;25(1):267
Genome biology 2024 Oct 14;25(1):267
Preliminary study of the role of histone deacetylase (HDAC) in steroid-induced avascular necrosis of the femoral head induced by BMSC adipogenic differentiation.
Yu YL, Duan P, Zheng L, Xu JM, Pan ZY
Journal of orthopaedic surgery and research 2024 Oct 12;19(1):645
Journal of orthopaedic surgery and research 2024 Oct 12;19(1):645
Chromatin Licensing and DNA Replication Factor 1 (CDT1) Is a Potential Prognostic Biomarker Involved in the Malignant Biological Behavior of Glioma.
Chen T, Meng J, Yu K, Huang T, Zhao J
ACS pharmacology & translational science 2024 Oct 11;7(10):3131-3143
ACS pharmacology & translational science 2024 Oct 11;7(10):3131-3143
Investigating PPT2's role in ovarian cancer prognosis and immunotherapy outcomes.
Xu H, Zhang Y, Xie Z, Xie XF, Qiao WL, Wang M, Zhao BB, Hua T
Journal of ovarian research 2024 Oct 11;17(1):198
Journal of ovarian research 2024 Oct 11;17(1):198
Enhanced interactions within microenvironment accelerates dismal prognosis in HBV-related HCC after TACE.
Wang L, Cao J, Liu Z, Wu S, Liu Y, Liang R, Zhu R, Wang W, Li J, Sun Y
Hepatology communications 2024 Oct 1;8(10)
Hepatology communications 2024 Oct 1;8(10)
The reduction of imidazole propionate induced by intermittent fasting promotes recovery of peripheral nerve injury by enhancing migration of Schwann cells.
Tang W, Yin X, Liu K, Shao T, Gao Q, Shen H, Zhong X, Zhang Z
Experimental cell research 2024 Oct 1;442(2):114261
Experimental cell research 2024 Oct 1;442(2):114261
Lipoxin A4 modulates the PKA/CREB and NF-κB signaling pathway to mitigate chondrocyte catabolism and apoptosis in temporomandibular joint osteoarthritis.
Tuerxun P, Ng T, Sun J, Ou F, Jia X, Zhao K, Zhu P
Experimental cell research 2024 Oct 1;442(2):114249
Experimental cell research 2024 Oct 1;442(2):114249
The role of ALDH1A1 in glioblastoma proliferation and invasion.
Huang YK, Wang TM, Chen CY, Li CY, Wang SC, Irshad K, Pan Y, Chang KC
Chemico-biological interactions 2024 Oct 1;402:111202
Chemico-biological interactions 2024 Oct 1;402:111202
Peripheral dopamine suppression and elevated cystatin C in early diabetic nephropathy in spontaneously diabetic rats.
Horita S, Watanabe G, Misaka S, Taira S, Satoh M, Maejima Y, Shimomura K, Shimabukuro M, Kazama JJ, Shigetomi S
American journal of physiology. Renal physiology 2024 Oct 1;327(4):F581-F590
American journal of physiology. Renal physiology 2024 Oct 1;327(4):F581-F590
Endoplasmic reticulum stress promotes oxidative stress, inflammation, and apoptosis: A novel mechanism of citrinin-induced renal injury and dysfunction.
Wang Y, Li Y, Wu Y, Wu A, Xiao B, Liu X, Zhang Q, Feng Y, Yuan Z, Yi J, Wu J, Yang C
Ecotoxicology and environmental safety 2024 Oct 1;284:116946
Ecotoxicology and environmental safety 2024 Oct 1;284:116946
Apoptosis mediated by crosstalk between mitochondria and endoplasmic reticulum: A possible cause of citrinin disruption of the intestinal barrier.
Li Y, Wang Y, Jiang Z, Yang C, Wu Y, Wu A, Zhang Q, Liu X, Xiao B, Feng Y, Wu J, Liang Z, Yuan Z
Ecotoxicology and environmental safety 2024 Oct 1;284:116877
Ecotoxicology and environmental safety 2024 Oct 1;284:116877
Modulation of choline and lactate metabolism by basic fibroblast growth factor mitigates neuroinflammation in type 2 diabetes: Insights from (1)H-NMR metabolomics analysis.
Wu Y, Wang X, Zhang W, Fu J, Jiang K, Shen Y, Li C, Gao H
Neuropharmacology 2024 Oct 1;257:110049
Neuropharmacology 2024 Oct 1;257:110049
Mitochondrial calcium uniporter knockdown in hippocampal neurons alleviates anxious and depressive behavior in the 3XTG Alzheimer's disease mouse model.
Wang Y, Wu LH, Hou F, Wang ZJ, Wu MN, Hölscher C, Cai HY
Brain research 2024 Oct 1;1840:149060
Brain research 2024 Oct 1;1840:149060
Isoliquiritigenin alleviates cerebral ischemia-reperfusion injury by reducing oxidative stress and ameliorating mitochondrial dysfunction via activating the Nrf2 pathway.
Lan X, Wang Q, Liu Y, You Q, Wei W, Zhu C, Hai D, Cai Z, Yu J, Zhang J, Liu N
Redox biology 2024 Nov;77:103406
Redox biology 2024 Nov;77:103406
Serum exosomal miRNA promote glioma progression by targeting SOS1 via abscopal effect of radiation.
Zhang Y, Xie J, Zhang H, Li J, Mi X, Zhou X, Ding Z
Archives of biochemistry and biophysics 2024 Nov;761:110138
Archives of biochemistry and biophysics 2024 Nov;761:110138
Stratifin (SFN) Regulates Cervical Cancer Cell Proliferation, Apoptosis, and Cytoskeletal Remodeling and Metastasis Progression Through LIMK2/Cofilin Signaling.
Du N, Li D, Zhao W, Liu Y
Molecular biotechnology 2024 Nov;66(11):3369-3381
Molecular biotechnology 2024 Nov;66(11):3369-3381
Hyperoxia can Induce Lung Injury by Upregulating AECII Autophagy and Apoptosis Via the mTOR Pathway.
Ren Y, Qin S, Liu X, Feng B, Liu J, Zhang J, Yuan P, Yu K, Mei H, Chen M
Molecular biotechnology 2024 Nov;66(11):3357-3368
Molecular biotechnology 2024 Nov;66(11):3357-3368
An interpretable artificial intelligence framework for designing synthetic lethality-based anti-cancer combination therapies.
Wang J, Wen Y, Zhang Y, Wang Z, Jiang Y, Dai C, Wu L, Leng D, He S, Bo X
Journal of advanced research 2024 Nov;65:329-343
Journal of advanced research 2024 Nov;65:329-343
Quercetin inhibits endothelial & hepatocellular carcinoma cell crosstalk via reducing extracellular vesicle-mediated VEGFR2 mRNA transfer.
Xiong W, Zheng B, Liu D, Pu M, Zhou S, Deng Y
Molecular carcinogenesis 2024 Nov;63(11):2254-2268
Molecular carcinogenesis 2024 Nov;63(11):2254-2268
ELMO1 regulates macrophage directed migration and attenuates inflammation via NF-κB signaling pathway in primary biliary cholangitis.
Ma D, Liu X, Li J, Wu H, Ma J, Tai W
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2024 Nov;56(11):1897-1905
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2024 Nov;56(11):1897-1905
PM(10) dysregulates epithelial barrier function in human corneal epithelial cells that is restored by antioxidant SKQ1.
Somayajulu M, Wright R, Muhammed F, McClellan SA, Ibrahim A, Hazlett LD
Toxicology and applied pharmacology 2024 Nov;492:117122
Toxicology and applied pharmacology 2024 Nov;492:117122
Inhibition of BCAT1 expression improves recurrent miscarriage by regulating cellular dysfunction and inflammation of trophoblasts.
Xu G, Tian C, Li Y, Fang L, Wang J, Jing Z, Li S, Chen P
Cell and tissue research 2024 Nov;398(2):111-121
Cell and tissue research 2024 Nov;398(2):111-121
SPAG4 enhances mitochondrial respiration and aerobic glycolysis in colorectal cancer cells by activating the PI3K/Akt signaling pathway.
Zhou J, Sun H, Zhou H, Liu Y
Journal of biochemical and molecular toxicology 2024 Nov;38(11):e70009
Journal of biochemical and molecular toxicology 2024 Nov;38(11):e70009
Ruscogenin Exerts Anxiolytic-Like Effect via Microglial NF-κB/MAPKs/NLRP3 Signaling Pathways in Mouse Model of Chronic Inflammatory Pain.
Qi JY, Jin YC, Wang XS, Yang LK, Lu L, Yue J, Yang F, Liu YS, Jiang YL, Song DK, Lv T, Li XB, Zhang K, Liu SB
Phytotherapy research : PTR 2024 Nov;38(11):5417-5440
Phytotherapy research : PTR 2024 Nov;38(11):5417-5440
Albumin-based co-loaded sonosensitizer and STING agonist nanodelivery system for enhanced sonodynamic and immune combination antitumor therapy.
Huang H, Du L, Su R, Li Z, Shao Y, Yuan Y, Wang C, Lu C, He Y, He H, Zhang C
Journal of controlled release : official journal of the Controlled Release Society 2024 Nov;375:524-536
Journal of controlled release : official journal of the Controlled Release Society 2024 Nov;375:524-536
PI3K/AKT/mTORC1 signalling pathway regulates MMP9 gene activation via transcription factor NF-κB in mammary epithelial cells of dairy cows.
Mao Y, Su C, Yang H, Ma X, Zhao F, Qu B, Yang Y, Hou X, Zhao B, Cui Y
Animal biotechnology 2024 Nov;35(1):2314100
Animal biotechnology 2024 Nov;35(1):2314100
N6-methyladenosine RNA methylation modification regulates the transcription of viral-derived E (XSR) miRNAs to promote ALV-J replication.
Cao Y, Ren Q, Chang S, Cui W, Zhao P, Wang Y
Veterinary microbiology 2024 Nov;298:110218
Veterinary microbiology 2024 Nov;298:110218
Data-mining-based biomarker evaluation and experimental validation of SHTN1 for bladder cancer.
Wang Y, Wang J, Zeng T, Qi J
Cancer genetics 2024 Nov;288-289:43-53
Cancer genetics 2024 Nov;288-289:43-53
PI4KB is an essential host factor for duck hepatitis a virus 1 replication and translation.
Li X, Wang M, Cheng A, Zhang W, Yang Q, Tian B, Ou X, Sun D, He Y, Zhao X, Wu Y, Zhang S, Huang J, Wu Z, Yu Y, Zhang L, Zhu D, Jia R, Liu M, Chen S
International journal of biological macromolecules 2024 Nov;281(Pt 3):136480
International journal of biological macromolecules 2024 Nov;281(Pt 3):136480
Methacrylated hyaluronic acid/laponite photosensitive, sustained-release hydrogel loaded with bilobalide for enhancing random flap survival through mitigation of endoplasmic reticulum stress.
Ye J, Yin X, Xie S, Hua Q, Zhu J, Chen J, Zheng W, Cai L
International journal of biological macromolecules 2024 Nov;281(Pt 1):136277
International journal of biological macromolecules 2024 Nov;281(Pt 1):136277
Intra-articular injection of platinum nanozyme-loaded silk fibroin/pullulan hydrogels relieves osteoarthritis through ROS scavenging and ferroptosis suppression.
Feng J, Deng X, Hao P, Zhu Z, Li T, Yuan X, Hu J, Wang Y
International journal of biological macromolecules 2024 Nov;280(Pt 2):135863
International journal of biological macromolecules 2024 Nov;280(Pt 2):135863
Structural insights into human zinc transporter ZnT1 mediated Zn(2+) efflux.
Long Y, Zhu Z, Zhou Z, Yang C, Chao Y, Wang Y, Zhou Q, Wang MW, Qu Q
EMBO reports 2024 Nov;25(11):5006-5025
EMBO reports 2024 Nov;25(11):5006-5025
Activation of BK channels prevents diabetes-induced osteopenia by regulating mitochondrial Ca(2+) and SLC25A5/ANT2-PINK1-PRKN-mediated mitophagy.
Jiang L, He H, Tang Y, Li J, Reilly S, Xin H, Li Z, Cai H, Zhang X
Autophagy 2024 Nov;20(11):2388-2404
Autophagy 2024 Nov;20(11):2388-2404
Mechanism of Gastrodin against neurotoxicity based on network pharmacology, molecular docking and experimental verification.
Guo H, Li C, Zhao J, Guo T, Chen S, Qin X, Zhu K, Zhang W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117611
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117611
TMT-based proteomics reveals methylprotodioscin alleviates oxidative stress and inflammation via COX6C in myocardial infraction.
Xu Z, Song T, Yang X, Cong L, Yin L, Xu Y, Han X, Gao M, Xu L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117489
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117489
Vitamin U alleviates AFB(1)-induced hepatotoxicity in pregnant and lactating mice by regulating the Nrf2/Hmox1 pathway.
Ling C, Liu S, Meng K, Wang Y, Zhang X, Liu J, Li X, Liu K, Deng H, Li C
Research in veterinary science 2024 Nov;180:105436
Research in veterinary science 2024 Nov;180:105436
Akt inhibitors prevent CyHV-2 infection in vitro.
Song Y, Zhang Y, Xiao S, Li P, Lu L, Wang H
Fish & shellfish immunology 2024 Nov;154:109940
Fish & shellfish immunology 2024 Nov;154:109940
A comparative study on the immune response in the head and trunk kidney of yellow catfish infected with Edwardsiella ictaluri.
Guo M, Sun R, Wu Z, Li A, Wang Q, Zhao Z, Liu H, Wang B, Xiao K, Shi Z, Ji W
Fish & shellfish immunology 2024 Nov;154:109895
Fish & shellfish immunology 2024 Nov;154:109895
Melanin resistance of heat-processed ginsenosides from Panax ginseng berry treated with citric acid through autophagy pathway.
Tan H, He X, Han L, Ren H, Chai J, Li M, Zhao W, Lee J, Liu S, Li X, Zhao Y
Bioorganic chemistry 2024 Nov;152:107758
Bioorganic chemistry 2024 Nov;152:107758
GBF1 deficiency causes cataracts in human and mouse.
Jia W, Zhang C, Luo Y, Gao J, Yuan C, Zhang D, Zhou X, Tan Y, Wang S, Chen Z, Li G, Zhang X
Human genetics 2024 Nov;143(11):1281-1291
Human genetics 2024 Nov;143(11):1281-1291
Matrix metalloproteinase-11 regulates inverted papilloma epithelial cell migration and invasion.
Panara K, Hui TL, Keshari D, Tong CCL, Palmer JN, Adappa ND, Douglas JE, Cohen NA, Kohanski MA
International forum of allergy & rhinology 2024 Nov;14(11):1714-1723
International forum of allergy & rhinology 2024 Nov;14(11):1714-1723
Tetrahedral Framework Nucleic Acid-Based Delivery of Astaxanthin Suppresses Chondrocyte Pyroptosis and Modulates Oxidative Stress for the Treatment of Osteoarthritis.
Li Y, Li J, Xu S, Li D, Zhang Z, Huang Q, Wang X, Shen M, Xu S
Advanced healthcare materials 2024 Nov;13(28):e2401452
Advanced healthcare materials 2024 Nov;13(28):e2401452
Erbin alleviates sepsis-induced cardiomyopathy by inhibiting RIPK1-dependent necroptosis through activating PKA/CREB pathway.
Zhou H, Gong H, Liu H, Jing G, Xia Y, Wang Y, Wu D, Yang C, Zuo J, Wang Y, Wu X, Song X
Cellular signalling 2024 Nov;123:111374
Cellular signalling 2024 Nov;123:111374
METTL3 -mediated m6A modification of circ_0000620 regulates cisplatin sensitivity and apoptosis in lung adenocarcinoma via the MiR-216b-5p/KRAS axis.
Li X, Wang Y, Cheng J, Qiu L, Wang R, Zhang Y, Wang H
Cellular signalling 2024 Nov;123:111349
Cellular signalling 2024 Nov;123:111349
Bifidobacterium pseudolongum-Derived Bile Acid from Dietary Carvacrol and Thymol Supplementation Attenuates Colitis via cGMP-PKG-mTORC1 Pathway.
Zhang K, Xu Y, Zheng Y, Zhang T, Wu Y, Yan Y, Lei Y, Cao X, Wang X, Yan F, Lei Z, Brugger D, Chen Y, Deng L, Yang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(43):e2406917
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(43):e2406917
The gut microbial metabolite indole-3-aldehyde alleviates impaired intestinal development by promoting intestinal stem cell expansion in weaned piglets.
Zhang J, Chen Y, Guo X, Li X, Zhang R, Wang M, Zhu W, Yu K
Journal of animal science and biotechnology 2024 Nov 8;15(1):150
Journal of animal science and biotechnology 2024 Nov 8;15(1):150
Engineered Hybrid Lantibiotic that Selectively Combats Infections Caused by Staphylococcus aureus.
He Y, Deng J, Zhong X, Dai S, Song X, Zou Y, Ye G, Zhou X, Yin Z, Wan H, Zhao X
ACS infectious diseases 2024 Nov 8;10(11):3891-3901
ACS infectious diseases 2024 Nov 8;10(11):3891-3901
S-ketamine alleviates depression-like behavior and hippocampal neuroplasticity in the offspring of mice that experience prenatal stress.
Zhang Y, Wei CK, Wang P, Zheng LC, Cheng Y, Ren ZH, Jin YH, Yao YY, Liu HZ
Scientific reports 2024 Nov 6;14(1):26929
Scientific reports 2024 Nov 6;14(1):26929
Sensing steroid hormone 17α-hydroxypregnenolone by GPR56 enables protection from ferroptosis-induced liver injury.
Lin H, Ma C, Zhuang X, Liu S, Liu D, Zhang M, Lu Y, Zhou G, Zhang C, Wang T, Zhang Z, Lv L, Zhang D, Ruan XZ, Xu Y, Chai R, Yu X, Sun JP, Chu B
Cell metabolism 2024 Nov 5;36(11):2402-2418.e10
Cell metabolism 2024 Nov 5;36(11):2402-2418.e10
The ZNF263/CPT1B axis regulates fatty acid β-oxidation to affect cisplatin resistance in lung adenocarcinoma.
Yan R, Zheng C, Qian S, Li K, Kong X, Liao S
The pharmacogenomics journal 2024 Nov 5;24(6):33
The pharmacogenomics journal 2024 Nov 5;24(6):33
Naringin Alleviates Intestinal Fibrosis by Inhibiting ER Stress-Induced PAR2 Activation.
Liu J, Xu L, Wang L, Wang Q, Yu L, Zhang S
Inflammatory bowel diseases 2024 Nov 4;30(11):1946-1956
Inflammatory bowel diseases 2024 Nov 4;30(11):1946-1956
GATA1-activated lncRNA OIP5-AS1 and GAS5 promote pyroptosis to exacerbate asthma through regulating miR-136-5p/LIFR axis.
Zhao S, Huang S, Wu Y, Yao X, Cai X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Nov 30;38(22):e70159
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Nov 30;38(22):e70159
Tumor Protein D53 (TPD53): Involvement in Malignant Transformation of Low-Malignant Oral Squamous Cell Carcinoma Cells.
Watanabe M, Mukudai Y, Kindaichi N, Nara M, Yamada K, Abe Y, Houri A, Shimane T, Shirota T
Biomedicines 2024 Nov 28;12(12)
Biomedicines 2024 Nov 28;12(12)
CAFs-derived lactate enhances the cancer stemness through inhibiting the MST1 ubiquitination degradation in OSCC.
Zhang S, Wang J, Chen Y, Liang W, Liu H, Du R, Sun Y, Hu C, Shang Z
Cell & bioscience 2024 Nov 27;14(1):144
Cell & bioscience 2024 Nov 27;14(1):144
Spatially organized tumor-stroma boundary determines the efficacy of immunotherapy in colorectal cancer patients.
Feng Y, Ma W, Zang Y, Guo Y, Li Y, Zhang Y, Dong X, Liu Y, Zhan X, Pan Z, Luo M, Wu M, Chen A, Kang D, Chen G, Liu L, Zhou J, Zhang R
Nature communications 2024 Nov 26;15(1):10259
Nature communications 2024 Nov 26;15(1):10259
Trehalose Alleviates D-Galactose-Induced Aging-Related Granulosa Cell Death in Ovaries.
Xi H, Chen X, Liang K, Wang X, Jiang F, Li Y, Niu D
International journal of molecular sciences 2024 Nov 25;25(23)
International journal of molecular sciences 2024 Nov 25;25(23)
Bovine NMRAL2 Protein Blunts Nitric Oxide Production and Inflammatory Response in Mycobacterium bovis Infected Bovine Lung Epithelial Cells.
Peng Y, Zhou S, Sun Q, Zhou X, Wang C, Wang Z, Iftakhar T, Zhu Y, Xie S, Chen X, Zhang L, Hu C, Chen Y, Guo A
Cells 2024 Nov 24;13(23)
Cells 2024 Nov 24;13(23)
Gastrodin attenuates diabetic cardiomyopathy characterized by myocardial fibrosis by inhibiting the KLK8-PAR1 signaling axis.
Zhang M, Zhang Y, He J, Wang X, Wang Y, Li L, Tao L, Zhang M, Shen X
Chinese medicine 2024 Nov 22;19(1):164
Chinese medicine 2024 Nov 22;19(1):164
Hyperoside induces ferroptosis in chronic myeloid leukemia cells by targeting NRF2.
Wei J, Chai Q, Qin Y, Li L, Guo C, Lu Z, Liu H
Molecular medicine (Cambridge, Mass.) 2024 Nov 21;30(1):224
Molecular medicine (Cambridge, Mass.) 2024 Nov 21;30(1):224
Ficolin-1 ameliorates pulmonary fibrosis via directly binding to TGF-β1.
Gao P, Lu Y, Tang K, Wang W, Wang T, Zhu Y, Zhao J, Mao Y
Journal of translational medicine 2024 Nov 21;22(1):1051
Journal of translational medicine 2024 Nov 21;22(1):1051
The Hydrophobic Amino Acid-Rich Fish Collagen Peptide Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice via Repairing the Intestinal Barrier, Regulating Intestinal Flora and AA Metabolism.
Yang L, Wang Y, Li X, Chen Y, Liang J, He L, Jiang D, Huang S, Hou S
Journal of agricultural and food chemistry 2024 Nov 20;72(46):25690-25703
Journal of agricultural and food chemistry 2024 Nov 20;72(46):25690-25703
The effect of paeoniflorin on the rewarding effect of methamphetamine and the associated cognitive impairment in mice.
Gong XS, Wang HX, Yang XD, Yu ZY, Lin SJ, Zou ZT, Lv JN, Qian LY, Ruan YE, Si ZZ, Zhou Y, Liu Y
Metabolic brain disease 2024 Nov 20;40(1):27
Metabolic brain disease 2024 Nov 20;40(1):27
The Regulatory Effect of Insulin-Like Growth Factor-2 on Hypothalamic Gonadotropin-Releasing Hormone Neurons during the Pubertal Period.
Dai X, He Y, Han X, Sun W, Yu J, Lin Y, Wang Y
Journal of integrative neuroscience 2024 Nov 20;23(11):208
Journal of integrative neuroscience 2024 Nov 20;23(11):208
Identifying genetic targets in clinical subtypes of Parkinson's disease for optimizing pharmacological treatment strategies.
Kong D, Li C, Ma L, Du L, Jiang N, Zhao X, Zhang S, Zhao Z, Fang L, Du G
Signal transduction and targeted therapy 2024 Nov 18;9(1):320
Signal transduction and targeted therapy 2024 Nov 18;9(1):320
Lentivirus-mediated Knockdown of Ski Improves Neurological Function After Spinal Cord Injury in Rats.
Wang ZQ, Ran R, Ma CW, Zhao GH, Zhou KS, Zhang HH
Neurochemical research 2024 Nov 16;50(1):15
Neurochemical research 2024 Nov 16;50(1):15
Investigating the mechanism of ferroptosis induction by sappanone A in hepatocellular carcinoma: NRF2/xCT/GPX4 axis.
Xing Y, Yang H, Dai C, Qiu Z, Guan Y, Zhang L
European journal of pharmacology 2024 Nov 15;983:176965
European journal of pharmacology 2024 Nov 15;983:176965
EHD1 promotes breast cancer metastasis through upregulating HIF2a expression via activating mTOR pathway.
Gao X, Li J, Feng X, Xie Y, Zhang J, Liu J, Wang B, Liu P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Nov 15;38(21):e70168
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Nov 15;38(21):e70168
Single-cell sequencing combined with transcriptomics and in vivo and in vitro analysis reveals the landscape of ferroptosis in myocardial ischemia-reperfusion injury.
Zhong C, Dong H, Ma Y, Zhuang B, Shi H, Hong L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Nov 15;38(21):e70164
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Nov 15;38(21):e70164
Hippocampal cannabinoid type 2 receptor alleviates chronic neuropathic pain-induced cognitive impairment via microglial DUSP6 pathway in rats.
Xu L, Zhu A, Xu S, Zhao J, Song S, Zhu H, Huang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Nov 15;38(21):e70152
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Nov 15;38(21):e70152
D-glucaro-1,4-lactone improves Diethylnitrosamine induced hepatocellular carcinoma in rats via the uric acid-ROS pathway.
Cai H, Zhang Y, Wang J, Deng Y, Liu J, Wu Z, Cao D, Song Z, Wang L, Xie B
Journal of ethnopharmacology 2024 Nov 15;334:118569
Journal of ethnopharmacology 2024 Nov 15;334:118569
The protective role of Cordyceps cicadae and its active ingredient myriocin against sodium iodate-induced age-related macular degeneration via an anti-necroptotic TNF-RIPK1/3 pathway.
Ma SZ, Dong S, Zhou ZY, Ji XY, Zhang YY, Wang XQ, Zhang B
Journal of ethnopharmacology 2024 Nov 15;334:118565
Journal of ethnopharmacology 2024 Nov 15;334:118565
Human monocyte-derived macrophages shift subcellular metalloprotease activity depending on their activation state.
Bernaerts E, Ahmadzadeh K, De Visscher A, Malengier-Devlies B, Häuβler D, Mitera T, Martens E, Krüger A, De Somer L, Matthys P, Vandooren J
iScience 2024 Nov 15;27(11):111171
iScience 2024 Nov 15;27(11):111171
Effect of exercise during pregnancy on offspring development through ameliorating high glucose and hypoxia in gestational diabetes mellitus.
Tang YB, Wang LS, Wu YH, Zhang LX, Hu LY, Wu Q, Zhou ML, Liang ZX
World journal of diabetes 2024 Nov 15;15(11):2203-2219
World journal of diabetes 2024 Nov 15;15(11):2203-2219
Gastrodin against oxidative stress-inflammation crosstalk via inhibiting mtDNA/TLR9 and JAK2/STAT3 signaling to ameliorate ischemic stroke injury.
Zhang M, Zhang Y, Peng J, Huang Y, Gong Z, Lu H, Han L, Wang D
International immunopharmacology 2024 Nov 15;141:113012
International immunopharmacology 2024 Nov 15;141:113012
HIF-1α knockdown attenuates phenotypic transformation and oxidative stress induced by high salt in human aortic vascular smooth muscle cells.
Deng W, Huang S, Yu L, Gao B, Pan Y, Wang X, Li L
Scientific reports 2024 Nov 15;14(1):28100
Scientific reports 2024 Nov 15;14(1):28100
High-intensity interval training and moderate-intensity continuous training alleviate vascular dysfunction in spontaneously hypertensive rats through the inhibition of pyroptosis.
Li Y, Luo M, Chang Q, Cao S, Wang Y, Chen Z, Yang J, Liu G
Heliyon 2024 Nov 15;10(21):e39505
Heliyon 2024 Nov 15;10(21):e39505
Taraxerone inhibits M1 polarization and alleviates sepsis-induced acute lung injury by activating SIRT1.
Deng L, Xie W, Lin M, Xiong D, Huang L, Zhang X, Qian R, Huang X, Tang S, Liu W
Chinese medicine 2024 Nov 14;19(1):159
Chinese medicine 2024 Nov 14;19(1):159
Glial maturation factor-β deficiency prevents oestrogen deficiency-induced bone loss by remodelling the actin network to suppress adipogenesis of bone marrow mesenchymal stem cells.
Xu J, Huang Z, Shi S, Xia J, Chen G, Zhou K, Zhang Y, Bian C, Shen Y, Yin X, Lu L, Gu H
Cell death & disease 2024 Nov 14;15(11):829
Cell death & disease 2024 Nov 14;15(11):829
FXR deficiency induced ferroptosis via modulation of the CBP-dependent p53 acetylation to suppress breast cancer growth and metastasis.
Huang P, Zhao H, Dai H, Li J, Pan X, Pan W, Xia C, Liu F
Cell death & disease 2024 Nov 14;15(11):826
Cell death & disease 2024 Nov 14;15(11):826
The role of CISD1 reduction in macrophages in promoting COPD development through M1 polarization and mitochondrial dysfunction.
Gao J, Dong M, Tian W, Xia J, Qian Y, Jiang Z, Chen Z, Shen Y
European journal of medical research 2024 Nov 13;29(1):541
European journal of medical research 2024 Nov 13;29(1):541
Improvement of osteogenic differentiation potential of placenta-derived mesenchymal stem cells by metformin via AMPK pathway activation.
Manochantr S, Meesuk L, Chadee N, Suwanprateeb J, Tantrawatpan C, Kheolamai P
Stem cell research & therapy 2024 Nov 13;15(1):417
Stem cell research & therapy 2024 Nov 13;15(1):417
LncRNA GClnc1 promotes osteosarcoma progression by stabilizing NONO and blocking FBXW7-mediated ubiquitination.
Zhang J, Luo X, Guo C, Dai Z, Tang X, Zhang F, Jiao Q, Lin S, Zou L, Zhang Z, Lv XB
BMC cancer 2024 Nov 11;24(1):1375
BMC cancer 2024 Nov 11;24(1):1375
TIPE2 aggravates experimental colitis and disrupts intestinal epithelial barrier integrity by activating JAK2/STAT3/SOCS3 signal pathway.
Zeng L, Wang Y, Shen J, Wei X, Wu Y, Chi X, Zheng X, Yu X, Shi Y, Liu W
Experimental cell research 2024 Nov 1;443(1):114287
Experimental cell research 2024 Nov 1;443(1):114287
Aerobic exercise modulates RIPK1-mediated MAP3K5/JNK and NF-κB pathways to suppress microglia activation and neuroinflammation in the hippocampus of D-gal-induced accelerated aging mice.
Liu Y, Meng X, Tang C, Zheng L, Tao K, Guo W
Physiology & behavior 2024 Nov 1;286:114676
Physiology & behavior 2024 Nov 1;286:114676
Hepatocyte-derived Fetuin-A promotes alcohol-associated liver disease in mice by inhibiting autophagy-lysosome degradation of TLR and M2 macrophage polarization.
Lu S, Jin H, Nong T, Li D, Long K, Chen Y, Li Y, Xing H, Pan T, He S, Jiang K, Zhong F
Free radical biology & medicine 2024 Nov 1;224:506-520
Free radical biology & medicine 2024 Nov 1;224:506-520
Protective effects of a novel bicyclic γ-butyrolactone compound against H(2)O(2) or corticosterone-induced neural cell apoptosis.
Zhang Z, Li X, Zhuang Q, Xu X, Zhang X, Cui M, Wang Y, Li H
Brain research 2024 Nov 1;1842:149099
Brain research 2024 Nov 1;1842:149099
Hydrogen sulfide upregulates SIRT1 to inhibit ox-HDL-induced endothelial cell damage and mitochondrial dysfunction.
Zhao Y, Wang Y, Zheng H, Xu Q, Zhou K, Liu H, Xia Y, Wei DH, Jiang M, Tang ZH, Liu LS, Zheng H, Jiang Z
Nitric oxide : biology and chemistry 2024 Nov 1;152:78-89
Nitric oxide : biology and chemistry 2024 Nov 1;152:78-89
Luteolin prevents cadmium-induced PC12 cell death by suppressing the Akt/mTOR signaling pathway.
Zhang X, Xu W, Li H, Ruan D, Chen S, Chu N, Zhen Q, Wang Y
Medicine 2024 Nov 1;103(44):e40372
Medicine 2024 Nov 1;103(44):e40372
Itaconate inhibits corticosterone-induced necroptosis and neuroinflammation via up-regulating menin in HT22 cells.
Liang JY, Gao S, Jiang JM, Zhang P, Zou W, Tang XQ, Tang YY
Journal of physiology and biochemistry 2024 May;80(2):393-405
Journal of physiology and biochemistry 2024 May;80(2):393-405
TRIM29 facilitates gemcitabine resistance via MEK/ERK pathway and is modulated by circRPS29/miR-770-5p axis in PDAC.
Huang W, Hu X, He X, Pan D, Huang Z, Gu Z, Huang G, Wang P, Cui C, Fan Y
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 May;74:101079
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 May;74:101079
Stevioside Ameliorates Palmitic Acid-Induced Abnormal Glucose Uptake via the PDK4/AMPK/TBC1D1 Pathway in C2C12 Myotubes.
Zhang C, Li S, Li L, Wang R, Luo S, Li G
Endocrinology, diabetes & metabolism 2024 May;7(3):e00482
Endocrinology, diabetes & metabolism 2024 May;7(3):e00482
Glutaminase potentiates the glycolysis in esophageal squamous cell carcinoma by interacting with PDK1.
Zhu G, Guan F, Li S, Zhang Q, Zhang X, Qin Y, Sun Z, Peng S, Cheng J, Li Y, Ren R, Fan T, Liu H
Molecular carcinogenesis 2024 May;63(5):897-911
Molecular carcinogenesis 2024 May;63(5):897-911
Elevated serum levels of leukocyte cell-derived chemotaxin 2 are associated with the prevalence of metabolic syndrome.
Zheng X, Lu J, Xiang S, Zou P, Chen H, Liu J, Zeng C, He Y
Acta diabetologica 2024 May;61(5):643-655
Acta diabetologica 2024 May;61(5):643-655
Mogroside Ⅴ Inhibits M1 Polarization and Inflammation of Diabetic Mouse Macrophages via p38 MAPK/NF-Κb Signaling Pathway.
Dong X, Ye Z, Li C, Li K, Zhong X, Li H
Immunological investigations 2024 May;53(4):604-621
Immunological investigations 2024 May;53(4):604-621
Tetrahydrobiopterin (BH(4)) treatment stabilizes tyrosine hydroxylase: Rescue of tyrosine hydroxylase deficiency phenotypes in human neurons and in a knock-in mouse model.
Jung-Kc K, Tristán-Noguero A, Altankhuyag A, Piñol Belenguer D, Prestegård KS, Fernandez-Carasa I, Colini Baldeschi A, Sigatulina Bondarenko M, García-Cazorla A, Consiglio A, Martinez A
Journal of inherited metabolic disease 2024 May;47(3):494-508
Journal of inherited metabolic disease 2024 May;47(3):494-508
Epigallocatechin gallate alleviated the in vivo toxicity of ZnO nanoparticles to mouse intestine.
Wang C, Huang C, Cao Y
Journal of applied toxicology : JAT 2024 May;44(5):686-698
Journal of applied toxicology : JAT 2024 May;44(5):686-698
Exosomal lncRNA XIST promotes perineural invasion of pancreatic cancer cells via miR-211-5p/GDNF.
Cheng K, Pan J, Liu Q, Ji Y, Liu L, Guo X, Wang Q, Li S, Sun J, Gong M, Zhang Y, Yuan Y
Oncogene 2024 May;43(18):1341-1352
Oncogene 2024 May;43(18):1341-1352
Bakuchiol regulates TLR4/MyD88/NF-κB and Keap1/Nrf2/HO-1 pathways to protect against LPS-induced acute lung injury in vitro and in vivo.
Zhao L, Zhang Z, Li P, Gao Y, Shi Y
Naunyn-Schmiedeberg's archives of pharmacology 2024 May;397(5):3301-3312
Naunyn-Schmiedeberg's archives of pharmacology 2024 May;397(5):3301-3312
Suppression of long noncoding RNA SNHG6 alleviates cigarette smoke-induced lung inflammation by modulating NF-κB signaling.
Yang J, Yuan Y, Wang L, Deng G, Huang J, Liu Y, Gu W
Environmental toxicology 2024 May;39(5):2634-2641
Environmental toxicology 2024 May;39(5):2634-2641
Compensatory upregulation of MT2A alleviates neurogenic intermittent claudication through inhibiting activated p38 MAPK-mediated neuronal apoptosis.
Wang C, Wang Z, Zi Y, Dan X, Xu J, Zhao J, Xu W, Wu Z, Liu W, Ma B
Human cell 2024 May;37(3):675-688
Human cell 2024 May;37(3):675-688
Lacosamide alleviates bilateral cavernous nerve injury-induced erectile dysfunction in the rat model by ameliorating pathological changes in the corpus cavernosum.
Yao L, Cong R, Zhou X, Zhou X, Ji C, Wei X, Meng X, Song N
International journal of impotence research 2024 May;36(3):283-290
International journal of impotence research 2024 May;36(3):283-290
Joint Analysis of Genome-wide DNA Methylation and Transcription Sequencing Identifies the Role of BAX Gene in Heat Stress-Induced-Sertoli Cells Apoptosis.
Hu Y, Li Q, Qian Z, BeiXiao, Luo K, Luo N
Reproductive sciences (Thousand Oaks, Calif.) 2024 May;31(5):1311-1322
Reproductive sciences (Thousand Oaks, Calif.) 2024 May;31(5):1311-1322
Synaptic vesicle protein 2A mitigates parthanatos via apoptosis-inducing factor in a rat model of pharmacoresistant epilepsy.
Li C, Wang Z, Ren M, Ren S, Wu G, Wang L
CNS neuroscience & therapeutics 2024 May;30(5):e14778
CNS neuroscience & therapeutics 2024 May;30(5):e14778
Macrophage M2 polarization promotes pulpal inflammation resolution during orthodontic tooth movement.
Li J, Ren H, Zhang Z, Zhang J, Wei F
Journal of cellular and molecular medicine 2024 May;28(9):e18350
Journal of cellular and molecular medicine 2024 May;28(9):e18350
Prognostic and immunotherapeutic implications of bilirubin metabolism-associated genes in lung adenocarcinoma.
Ren K, Ling X, Chen L, Li Z, Huang T
Journal of cellular and molecular medicine 2024 May;28(9):e18346
Journal of cellular and molecular medicine 2024 May;28(9):e18346
Transcriptome analysis and functional verification reveal the roles of copper in resistance to potato virus Y infection in tobacco.
Guo H, Xu C, Wang F, Jiang L, Zhang Y, Wang L, Liu D, Zhao J, Xia C, Gu Y, Wang Z, An M, Xia Z, Wu Y
Pesticide biochemistry and physiology 2024 May;201:105893
Pesticide biochemistry and physiology 2024 May;201:105893
Regulation of Glucose Metabolism for Cell Energy Supply In Situ via High-Energy Intermediate Fructose Hydrogels.
Lu B, Zhao Q, Cai Z, Qian S, Mao J, Zhang L, Mao X, Sun X, Cui W, Zhang Y
Small (Weinheim an der Bergstrasse, Germany) 2024 May;20(19):e2309060
Small (Weinheim an der Bergstrasse, Germany) 2024 May;20(19):e2309060
Metal-Organic Framework-Mediated Synergistic Hypoxia-Activated Chemo-Immunotherapy Induced by High Intensity Focused Ultrasound for Enhanced Cancer Theranostics.
Sun T, Li J, Zhou Y, Zeng C, Luo C, Luo X, Li H
Small (Weinheim an der Bergstrasse, Germany) 2024 May;20(18):e2306338
Small (Weinheim an der Bergstrasse, Germany) 2024 May;20(18):e2306338
Endoplasmic reticulum stress-induced necroptosis promotes cochlear inflammation: Implications for age-related hearing loss.
Su Z, Liu Y, Zhang W, Liang W, Chen Y, Cao J, Liu Y, Zheng Y, Li Q
Experimental gerontology 2024 May;189:112401
Experimental gerontology 2024 May;189:112401
Inhibition of piezo1 prevents chronic cerebral hypoperfusion-induced cognitive impairment and blood brain barrier disruption.
Xu F, Xin Q, Ren M, Shi P, Wang B
Neurochemistry international 2024 May;175:105702
Neurochemistry international 2024 May;175:105702
Iguratimod inhibits protein citrullination and inflammation by downregulating NBCe2 in patients with rheumatoid arthritis.
Peng T, Li B, Bi L, Zhang F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116551
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116551
Epigallocatechin-3-gallate confers protection against myocardial ischemia/reperfusion injury by inhibiting ferroptosis, apoptosis, and autophagy via modulation of 14-3-3η.
Hu T, Hu FJ, Huang H, Zhang ZY, Qiao YM, Huang WX, Wang YC, Tang XY, Lai SQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116542
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116542
Vascular endothelial glycocalyx shedding in ventilator-induced lung injury in rats.
Ou D, Xu W, Feng Z, Yang Y, Xue W, Zhang Q, Li X, Zhu Y, Huang J, Fang Y
Microvascular research 2024 May;153:104658
Microvascular research 2024 May;153:104658
Single cell RNA-sequencing reveals the cellular senescence of placental mesenchymal stem/stromal cell in preeclampsia.
Zhang Y, Zhong Y, Yu Z, Cheng X, Zou L, Liu X
Placenta 2024 May;150:39-51
Placenta 2024 May;150:39-51
Tiliroside disrupted iron homeostasis and induced ferroptosis via directly targeting calpain-2 in pancreatic cancer cells.
Xu M, Zhong W, Yang C, Liu M, Yuan X, Lu T, Li D, Zhang G, Liu H, Zeng Y, Yang X, Zhou Y, Zhou L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 May;127:155392
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 May;127:155392
Development and Application of the CRISPR-dcas13d-eIF4G Translational Regulatory System to Inhibit Ferroptosis in Calcium Oxalate Crystal-Induced Kidney Injury.
He Z, Song C, Li S, Dong C, Liao W, Xiong Y, Yang S, Liu Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(17):e2309234
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(17):e2309234
Protective effects of sodium humate and its zinc and selenium chelate on the oxidative stress, inflammatory, and intestinal barrier damage of Salmonella Typhimurium-challenged broiler chickens.
Fan Y, Zhou W, Li G, Liu X, Zhong P, Liu K, Liu Y, Wang D
Poultry science 2024 May;103(5):103541
Poultry science 2024 May;103(5):103541
MKP1 may be involved in the occurrence of depression by regulating hippocampal autophagy in rats.
Feng L, Wang H, Chen C, Fu J, Zhao L, Zhao X, Geng M, Ren M, Tong L, Li Y, Gu J, Wang C
Behavioural brain research 2024 May 8;465:114962
Behavioural brain research 2024 May 8;465:114962
D-mannose alleviates intervertebral disc degeneration through glutamine metabolism.
Dong ZL, Jiao X, Wang ZG, Yuan K, Yang YQ, Wang Y, Li YT, Wang TC, Kan TY, Wang J, Tao HR
Military Medical Research 2024 May 6;11(1):28
Military Medical Research 2024 May 6;11(1):28
Blocking of FGFR4 signaling by F30 inhibits hepatocellular carcinoma cell proliferation through HMOX1-dependent ferroptosis pathway.
Huang F, Shi X, Hu M, Yan H, Li X, Ding Y, Zheng X, Cai X, Dai S, Xia Q, Cai Y
European journal of pharmacology 2024 May 5;970:176493
European journal of pharmacology 2024 May 5;970:176493
Naringenin reduces oxidative stress and necroptosis, apoptosis, and pyroptosis in random-pattern skin flaps by enhancing autophagy.
Jiang S, Ma F, Lou J, Li J, Shang X, Li Y, Wu J, Xu S
European journal of pharmacology 2024 May 5;970:176455
European journal of pharmacology 2024 May 5;970:176455
Ovarian PERK/NRF2/CX43/StAR/progesterone pathway activation mediates female reproductive dysfunction induced by cold exposure.
Ding M, Lu Y, Wen Q, Xing C, Huang X, Zhang Y, Wang W, Zhang C, Zhang M, Meng F, Liu K, Liu G, Song L
Scientific reports 2024 May 4;14(1):10248
Scientific reports 2024 May 4;14(1):10248
miR-4645-3p attenuates podocyte injury and mitochondrial dysfunction in diabetic kidney disease by targeting Cdk5.
Zhang Y, Xia S, Tian X, Yuan L, Gao Y, Liu D, Qi H, Wang S, Liu Z, Li Y, Zhao Z, Liu W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23668
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23668
FGF13 enhances the function of TRPV1 by stabilizing microtubules and regulates acute and chronic itch.
Dong ZS, Zhang XR, Xue DZ, Liu JH, Yi F, Zhang YY, Xian FY, Qiao RY, Liu BY, Zhang HL, Wang C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23661
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23661
Transgenic female mice producing trans 10, cis 12-conjugated linoleic acid present excessive prostaglandin E2, adrenaline, corticosterone, glucagon, and FGF21.
Rao Y, Liang LW, Li MJ, Wang YY, Wang BZ, Gou KM
Scientific reports 2024 May 30;14(1):12430
Scientific reports 2024 May 30;14(1):12430
EGCG suppresses PD-1 expression of T cells via inhibiting NF-κB phosphorylation and nuclear translocation.
Li ZD, Liu F, Zeng Y, Liu Y, Luo W, Yuan F, Li S, Li Q, Chen J, Fujita M, Zhang G, Li Y
International immunopharmacology 2024 May 30;133:112069
International immunopharmacology 2024 May 30;133:112069
Icariside I reduces breast cancer proliferation, apoptosis, invasion, and metastasis probably through inhibiting IL-6/STAT3 signaling pathway.
Hou M, Li H, He T, Hui S, Dai W, Hou X, Zhao J, Zhao J, Wen J, Kan W, Xiao X, Zhan X, Bai Z
The Journal of pharmacy and pharmacology 2024 May 3;76(5):499-513
The Journal of pharmacy and pharmacology 2024 May 3;76(5):499-513
Comparative Proteomics Elucidates the Potential Mechanism of Sperm Capacitation of Chinese Mitten Crabs (Eriocheir sinensis).
Cui X, Cai X, Zhang F, Zhang W, Liu H, Mu S, Guo S, Wan H, Zhang H, Zhang Z, Kang X
Journal of proteome research 2024 May 3;23(5):1603-1614
Journal of proteome research 2024 May 3;23(5):1603-1614
Contrasting Impacts of Ubiquitin Overexpression on Arabidopsis Growth and Development.
Yu P, Gao Z, Hua Z
Plants (Basel, Switzerland) 2024 May 28;13(11)
Plants (Basel, Switzerland) 2024 May 28;13(11)
Inhibition of lysosomal TRPML1 channel eliminates breast cancer stem cells by triggering ferroptosis.
Fan C, Wu H, Du X, Li C, Zeng W, Qu L, Cang C
Cell death discovery 2024 May 27;10(1):256
Cell death discovery 2024 May 27;10(1):256
Investigation of Uterine Fluid Extracellular Vesicles' Proteomic Profiles Provides Novel Diagnostic Biomarkers of Bovine Endometritis.
Piibor J, Waldmann A, Prasadani M, Kavak A, Andronowska A, Klein C, Kodithuwakku S, Fazeli A
Biomolecules 2024 May 25;14(6)
Biomolecules 2024 May 25;14(6)
Improved Immunotherapy Outcomes via Cuproptosis Upregulation of HLA-DRA Expression: Promoting the Aggregation of CD4(+) and CD8(+)T Lymphocytes in Clear Cell Renal Cell Carcinoma.
Wang B, Liu Y, Xiong F, Wang C
Pharmaceuticals (Basel, Switzerland) 2024 May 24;17(6)
Pharmaceuticals (Basel, Switzerland) 2024 May 24;17(6)
Activation of Nrf2/HO-1 signaling pathway exacerbates cholestatic liver injury.
Wang Y, Fu X, Zeng L, Hu Y, Gao R, Xian S, Liao S, Huang J, Yang Y, Liu J, Jin H, Klaunig J, Lu Y, Zhou S
Communications biology 2024 May 23;7(1):621
Communications biology 2024 May 23;7(1):621
Water extract of moschus alleviates erastin-induced ferroptosis by regulating the Keap1/Nrf2 pathway in HT22 cells.
Song C, Chu Z, Dai J, Xie D, Qin T, Xie L, Zhai Z, Huang S, Xu Y, Sun T
Journal of ethnopharmacology 2024 May 23;326:117937
Journal of ethnopharmacology 2024 May 23;326:117937
Integration of serum pharmacochemistry and metabolomics to reveal the underlying mechanism of shaoyao-gancao-fuzi decoction to ameliorate rheumatoid arthritis.
Li Z, Yuan J, Dai Y, Xia Y
Journal of ethnopharmacology 2024 May 23;326:117910
Journal of ethnopharmacology 2024 May 23;326:117910
Shaoyao decoction improves damp-heat colitis by activating the AHR/IL-22/STAT3 pathway through tryptophan metabolism driven by gut microbiota.
Zhang Y, Han L, Dong J, Yuan Z, Yao W, Ji P, Hua Y, Wei Y
Journal of ethnopharmacology 2024 May 23;326:117874
Journal of ethnopharmacology 2024 May 23;326:117874
Free total rhubarb anthraquinones protect intestinal mucosal barrier of SAP rats via inhibiting the NLRP3/caspase-1/GSDMD pyroptotic pathway.
Zeng Y, Liu X, Yi Q, Qiao G, Wang L, Chen L, Fan L, Li Y, Duan L, Huang L, Zhuang Q, Zhou Y, Xiong Y
Journal of ethnopharmacology 2024 May 23;326:117873
Journal of ethnopharmacology 2024 May 23;326:117873
An integrated network pharmacology, molecular docking and experiment validation study to investigate the potential mechanism of Isobavachalcone in the treatment of osteoarthritis.
Fan Y, Yin L, Zhong X, He Z, Meng X, Chai F, Kong M, Zhang Q, Xia C, Tong Y, Bi Q
Journal of ethnopharmacology 2024 May 23;326:117827
Journal of ethnopharmacology 2024 May 23;326:117827
HIV-1 with gag processing defects activates cGAS sensing.
Sumner RP, Blest H, Lin M, Maluquer de Motes C, Towers GJ
Retrovirology 2024 May 23;21(1):10
Retrovirology 2024 May 23;21(1):10
Microglial CMPK2 promotes neuroinflammation and brain injury after ischemic stroke.
Guan X, Zhu S, Song J, Liu K, Liu M, Xie L, Wang Y, Wu J, Xu X, Pang T
Cell reports. Medicine 2024 May 21;5(5):101522
Cell reports. Medicine 2024 May 21;5(5):101522
Targeting osteopontin alleviates endometriosis and inflammation by inhibiting the RhoA/ROS axis and achieves non-invasive in vitro detection via menstrual blood.
Wang H, Wang B, Wu M, Lu J, Duan P
Human reproduction (Oxford, England) 2024 May 2;39(5):1057-1071
Human reproduction (Oxford, England) 2024 May 2;39(5):1057-1071
Effect of Akkermansia muciniphila on pancreatic islet β-cell function in rats with prediabetes mellitus induced by a high-fat diet.
Yan S, Chen L, Li N, Wei X, Wang J, Dong W, Wang Y, Shi J, Ding X, Peng Y
Bioresources and bioprocessing 2024 May 19;11(1):51
Bioresources and bioprocessing 2024 May 19;11(1):51
Effect of total flavonoids of Dracocephalum moldavica L. On neuroinflammation in Alzheimer's disease model amyloid-β (Aβ1-42)-peptide-induced astrocyte activation.
Ren W, Yan XS, Fan JC, Huo DS, Wang XX, Jia JX, Yang ZJ
Journal of toxicology and environmental health. Part A 2024 May 18;87(10):436-447
Journal of toxicology and environmental health. Part A 2024 May 18;87(10):436-447
HSP70 positively regulates translation by interacting with the IRES and stabilizes the viral structural proteins VP1 and VP3 to facilitate duck hepatitis A virus type 1 replication.
Jiang Y, Xu C, Cheng A, Wang M, Zhang W, Zhao X, Yang Q, Wu Y, Zhang S, Tian B, Huang J, Ou X, Sun D, He Y, Wu Z, Zhu D, Jia R, Chen S, Liu M
Veterinary research 2024 May 17;55(1):63
Veterinary research 2024 May 17;55(1):63
The acetylation of MDH1 and IDH1 is associated with energy metabolism in acute liver failure.
Shi C, Zhang Y, Chen Q, Wang Y, Zhang D, Guo J, Zhang Q, Zhang W, Gong Z
iScience 2024 May 17;27(5):109678
iScience 2024 May 17;27(5):109678
Resveratrol protects cardiomyocytes against ischemia/reperfusion-induced ferroptosis via inhibition of the VDAC1/GPX4 pathway.
Hu T, Zou HX, Zhang ZY, Wang YC, Hu FJ, Huang WX, Liu JC, Lai SQ, Huang H
European journal of pharmacology 2024 May 15;971:176524
European journal of pharmacology 2024 May 15;971:176524
Puerarin Delays Mammary Gland Aging by Regulating Gut Microbiota and Inhibiting the p38MAPK Signaling Pathway.
Liu S, Hu H, Zhang M, Zhang Y, Geng R, Jin Y, Cao Y, Guo W, Liu J, Fu S
Journal of agricultural and food chemistry 2024 May 15;72(19):10879-10896
Journal of agricultural and food chemistry 2024 May 15;72(19):10879-10896
Cadmium exposure induced neuronal ferroptosis and cognitive deficits via the mtROS-ferritinophagy pathway.
Wang D, Wu Y, Zhou X, Liang C, Ma Y, Yuan Q, Wu Z, Hao X, Zhu X, Li X, Shi J, Chen J, Fan H
Environmental pollution (Barking, Essex : 1987) 2024 May 15;349:123958
Environmental pollution (Barking, Essex : 1987) 2024 May 15;349:123958
Microcystin-RR promote lipid accumulation through CD36 mediated signal pathway and fatty acid uptake in HepG2 cells.
Jia W, Zhong L, Ren Q, Teng D, Gong L, Dong H, Li J, Wang C, He YX, Yang J
Environmental research 2024 May 15;249:118402
Environmental research 2024 May 15;249:118402
Pharmacodynamics and mechanism of Erigeron breviscapus granules in the treatment of ischemic stroke in mice by regulating sphingolipid metabolism based on metabolomics.
Liu C, Liu K, Tao X, Li W, Zhao S, Dai Q, Yao H, Mu F, Chen S, Li J, Dong T, Duan J, Wei P, Gao F, Xi M
Journal of pharmaceutical and biomedical analysis 2024 May 15;242:116058
Journal of pharmaceutical and biomedical analysis 2024 May 15;242:116058
The changes of neurogenesis in the hippocampal dentate gyrus of SAMP8 mice and the effects of acupuncture and moxibustion.
Liu X, Chen J, Du Y, Tian Q, Wang L, Li W, Liu G, Tan Q, Wang J, Deng X
Brain research 2024 May 15;1831:148814
Brain research 2024 May 15;1831:148814
Activin and Hepatocyte Growth Factor Promotes Colorectal Cancer Stemness and Metastasis through FOXM1/SOX2/CXCR4 Signaling.
Peng H, Ye T, Deng L, Yang X, Li Q, Tong J, Guo J
Gut and liver 2024 May 15;18(3):476-488
Gut and liver 2024 May 15;18(3):476-488
High expression of SRSF1 facilitates osteosarcoma progression and unveils its potential mechanisms.
Li S, Huang X, Zheng S, Zhang W, Liu F, Cao Q
BMC cancer 2024 May 12;24(1):580
BMC cancer 2024 May 12;24(1):580
Regulation of cerebral blood flow boosts precise brain targeting of vinpocetine-derived ionizable-lipidoid nanoparticles.
Bian X, Yang L, Jiang D, Grippin AJ, Ma Y, Wu S, Wu L, Wang X, Tang Z, Tang K, Pan W, Dong S, Kim BYS, Jiang W, Yang Z, Li C
Nature communications 2024 May 11;15(1):3987
Nature communications 2024 May 11;15(1):3987
Palmatine inhibits expression fat mass and obesity associated protein (FTO) and exhibits a curative effect in dextran sulfate sodium (DSS)-induced experimental colitis.
Ji W, Huo Y, Zhang Y, Qian X, Ren Y, Hu C, Zhang J
International immunopharmacology 2024 May 10;132:111968
International immunopharmacology 2024 May 10;132:111968
The Role of SLIT3-ROBO4 Signaling in Endoplasmic Reticulum Stress-Induced Delayed Corneal Epithelial and Nerve Regeneration.
Chen R, Wang Y, Zhang Z, Wang X, Li Y, Wang M, Wang H, Dong M, Zhou Q, Yang L
Investigative ophthalmology & visual science 2024 May 1;65(5):8
Investigative ophthalmology & visual science 2024 May 1;65(5):8
DDX18 Facilitates the Tumorigenesis of Lung Adenocarcinoma by Promoting Cell Cycle Progression through the Upregulation of CDK4.
Feng B, Wang X, Qiu D, Sun H, Deng J, Tan Y, Ji K, Xu S, Zhang S, Tang C
International journal of molecular sciences 2024 May 1;25(9)
International journal of molecular sciences 2024 May 1;25(9)
Cubic liquid crystals containing propolis flavonoids as in situ thermo-sensitive hydrogel depots for periodontitis treatment: Preparation, pharmacodynamics and therapeutic mechanisms.
Tang M, Li J, Wang G, Wang Y, Peng C, Chang X, Tao Y, Guo J, Gui S
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2024 May 1;196:106762
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2024 May 1;196:106762
Design, synthesis, and evaluation of formylpiperazine analogs of Ferrostatin-1 as novel improved ferroptosis inhibitors.
Ji HL, Zhang YF, Zhang NY, Wang KM, Meng N, Zhang J, Jiang CS
Bioorganic & medicinal chemistry 2024 May 1;105:117716
Bioorganic & medicinal chemistry 2024 May 1;105:117716
Mammalian STE20-like kinase 1 inhibits synoviocytes activation in rheumatoid arthritis through mitochondrial dysfunction mediated by SIRT3/mTOR axis.
Tan M, Mao J, Zheng J, Meng Y, Li J, Hao J, Shen H
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Mar;73(3):415-432
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Mar;73(3):415-432
Enhanced VEGF secretion and blood-brain barrier disruption: Radiation-mediated inhibition of astrocyte autophagy via PI3K-AKT pathway activation.
Zhang S, Li M, Qiu Y, Wu J, Xu X, Ma Q, Zheng Z, Lu G, Deng Z, Huang H
Glia 2024 Mar;72(3):568-587
Glia 2024 Mar;72(3):568-587
Knockdown of ANGPTL4 inhibits adipogenesis of preadipocyte via autophagy.
Ling M, Qian H, Guo H
In vitro cellular & developmental biology. Animal 2024 Mar;60(3):258-265
In vitro cellular & developmental biology. Animal 2024 Mar;60(3):258-265
NLRP3 inflammasome mediates abnormal epithelial regeneration and distal lung remodeling in silica‑induced lung fibrosis.
Zhou H, Zhang Q, Liu C, Fan J, Huang W, Li N, Yang M, Wang H, Xie W, Kong H
International journal of molecular medicine 2024 Mar;53(3)
International journal of molecular medicine 2024 Mar;53(3)
14-3-3-η interacts with BCL-2 to protect human endothelial progenitor cells from ox-LDL-triggered damage.
Zhou H, Sun X, Dai Y, Wang X, Dai Z, Li X
Cell biology international 2024 Mar;48(3):290-299
Cell biology international 2024 Mar;48(3):290-299
BRMS1L confers anticancer activity in non-small cell lung cancer by transcriptionally inducing a redox imbalance in the GPX2-ROS pathway.
Cao P, Gu J, Liu M, Wang Y, Chen M, Jiang Y, Wang X, Zhu S, Gao X, Li S
Translational oncology 2024 Mar;41:101870
Translational oncology 2024 Mar;41:101870
A potential mechanism clue to the periodic storm from microglia activation and progressive neuron damage induced by paraquat exposure.
Shi G, Zhang C, Bai X, Sun J, Wang K, Meng Q, Li Y, Hu G, Hu R, Cai Q, Huang M
Environmental toxicology 2024 Mar;39(3):1874-1888
Environmental toxicology 2024 Mar;39(3):1874-1888
D-pinitol alleviates diabetic cardiomyopathy by inhibiting the optineurin-mediated endoplasmic reticulum stress and glycophagy signaling pathway.
Li X, Yu X, Yu F, Fu C, Zhao W, Liu X, Dai C, Gao H, Cheng M, Li B
Phytotherapy research : PTR 2024 Mar;38(3):1681-1694
Phytotherapy research : PTR 2024 Mar;38(3):1681-1694
A combination of PD-L1-targeted IL-15 mRNA nanotherapy and ultrasound-targeted microbubble destruction for tumor immunotherapy.
Wang X, Li F, Zhang J, Guo L, Shang M, Sun X, Xiao S, Shi D, Meng D, Zhao Y, Jiang C, Li J
Journal of controlled release : official journal of the Controlled Release Society 2024 Mar;367:45-60
Journal of controlled release : official journal of the Controlled Release Society 2024 Mar;367:45-60
Skin derived precursors induced Schwann cells mediated tissue engineering-aided neuroregeneration across sciatic nerve defect.
Xue C, Zhu H, Wang H, Wang Y, Xu X, Zhou S, Liu D, Zhao Y, Qian T, Guo Q, He J, Zhang K, Gu Y, Gong L, Yang J, Yi S, Yu B, Wang Y, Liu Y, Yang Y, Ding F, Gu X
Bioactive materials 2024 Mar;33:572-590
Bioactive materials 2024 Mar;33:572-590
SADS-CoV nsp1 inhibits the STAT1 phosphorylation by promoting K11/K48-linked polyubiquitination of JAK1 and blocks the STAT1 acetylation by degrading CBP.
Xiang Y, Mou C, Zhu L, Wang Z, Shi K, Bao W, Li J, Chen X, Chen Z
The Journal of biological chemistry 2024 Mar;300(3):105779
The Journal of biological chemistry 2024 Mar;300(3):105779
CD74-ROS1 L2026M mutant enhances autophagy through the MEK/ERK pathway to promote invasion, metastasis and crizotinib resistance in non-small cell lung cancer cells.
Xu X, Li Y, Xu R, Meng Y, Li Z, Zuo D, Wu Y
The FEBS journal 2024 Mar;291(6):1199-1219
The FEBS journal 2024 Mar;291(6):1199-1219
NDRG2 alleviates photoreceptor apoptosis by regulating the STAT3/TIMP3/MMP pathway in mice with retinal degenerative disease.
Chen T, Xiong Y, Deng C, Hu C, Li M, Quan R, Yu X
The FEBS journal 2024 Mar;291(5):986-1007
The FEBS journal 2024 Mar;291(5):986-1007
SIRT2-mediated deacetylation of ACLY promotes the progression of oesophageal squamous cell carcinoma.
Zhang X, Xu Y, Li S, Qin Y, Zhu G, Zhang Q, Zhang Y, Guan F, Fan T, Liu H
Journal of cellular and molecular medicine 2024 Mar;28(6):e18129
Journal of cellular and molecular medicine 2024 Mar;28(6):e18129
OTUD7B knockdown inhibits the proliferation and stemness of breast cancer cells by destabilizing FOXM1.
Wang H, Han S, Xiao J, Fu X, Chen W, Zhuo D
Oncology letters 2024 Mar;27(3):102
Oncology letters 2024 Mar;27(3):102
Integrin β8 prevents pericyte-myofibroblast transition and renal fibrosis through inhibiting the TGF-β1/TGFBR1/Smad3 pathway in diabetic kidney disease.
Cao Y, Su H, Zeng J, Xie Y, Liu Z, Liu F, Qiu Y, Yi F, Lin J, Hammes HP, Zhang C
Translational research : the journal of laboratory and clinical medicine 2024 Mar;265:36-50
Translational research : the journal of laboratory and clinical medicine 2024 Mar;265:36-50
Human RNA-binding protein HNRNPD interacts with and regulates the repair of deoxyribouridine in DNA.
Wang Z, Qu M, Chang S, Dai X, You C
International journal of biological macromolecules 2024 Mar;262(Pt 1):129951
International journal of biological macromolecules 2024 Mar;262(Pt 1):129951
VSIG4 inhibits RANKL-induced osteoclastogenesis by enhancing Nrf2-dependent antioxidant response against reactive oxygen species production.
Miao J, Tu Y, Jiang J, Ren R, Wu Q, Liang H, Wang T, Lin B, Wu J, Pan Y, Wang X, Jin H
International journal of biological macromolecules 2024 Mar;260(Pt 2):129357
International journal of biological macromolecules 2024 Mar;260(Pt 2):129357
Purification and structural characterization of two polysaccharides with anti-inflammatory activities from Plumbago zeylanica L.
Zhang X, Gao M, Zhao X, Qi Y, Xu L, Yin L, Peng J
International journal of biological macromolecules 2024 Mar;260(Pt 1):129455
International journal of biological macromolecules 2024 Mar;260(Pt 1):129455
Homoharringtonine induces apoptosis of mammary carcinoma cells by inhibiting the AKT/mTOR signaling pathway.
Zhang X, Mei C, Liang Z, Zhi Y, Xu H, Wang H, Dong H
Veterinary and comparative oncology 2024 Mar;22(1):57-69
Veterinary and comparative oncology 2024 Mar;22(1):57-69
Bioactive monoterpenoids and acetophenones from the aerial parts of Eupatorium fortunei.
Miao L, Wang ST, Wei QH, Ma RF, Zhang H
Phytochemistry 2024 Mar;219:113984
Phytochemistry 2024 Mar;219:113984
Alpha-ketoglutaric acid attenuates oxidative stress and modulates mitochondrial dynamics and autophagy of spleen in a piglet model of lipopolysaccharide-induced sepsis.
Liu G, Lu J, Sun W, Jia G, Zhao H, Chen X, Wang J
Free radical biology & medicine 2024 Mar;214:80-86
Free radical biology & medicine 2024 Mar;214:80-86
β-Sitosterol targets ASS1 for Nrf2 ubiquitin-dependent degradation, inducing ROS-mediated apoptosis via the PTEN/PI3K/AKT signaling pathway in ovarian cancer.
Wang H, Liu J, Zhang Z, Peng J, Wang Z, Yang L, Wang X, Hu S, Hong L
Free radical biology & medicine 2024 Mar;214:137-157
Free radical biology & medicine 2024 Mar;214:137-157
Baicalein ameliorates cognitive impairment of vascular dementia rats via suppressing neuroinflammation and regulating intestinal microbiota.
Song J, Li M, Kang N, Jin W, Xiao Y, Li Z, Qi Q, Zhang J, Duan Y, Feng X, Lv P
Brain research bulletin 2024 Mar;208:110888
Brain research bulletin 2024 Mar;208:110888
Luteolin ameliorates pentetrazole-induced seizures through the inhibition of the TLR4/NF-κB signaling pathway.
Cheng Y, Zhang Y, Huang P, Cheng Q, Ding H
Epilepsy research 2024 Mar;201:107321
Epilepsy research 2024 Mar;201:107321
IGF2BP3-stabilized CAMK1 regulates the mitochondrial dynamics of renal tubule to alleviate diabetic nephropathy.
Yuan D, Li H, Dai W, Zhou X, Zhou W, He L
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):167022
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):167022
USP46 enhances tamoxifen resistance in breast cancer cells by stabilizing PTBP1 to facilitate glycolysis.
Gao S, Wang Y, Xu Y, Liu L, Liu S
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):167011
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):167011
B-GOS alleviates olanzapine-induced lipid disturbances in mice by enriching Akkermansia and upregulation of PGRMC1-Wnt signaling.
Zeng C, Chen H, Cao T, Wang L, Jiao S, Lin C, Zhang B, Cai H
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Mar;185:114490
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Mar;185:114490
Extracellular vesicle mediated targeting delivery of growth differentiation factor-15 improves myocardial repair by reprogramming macrophages post myocardial injury.
Xiao T, Wei J, Cai D, Wang Y, Cui Z, Chen Q, Gu Q, Zou A, Mao L, Chi B, Ji Y, Wang Q, Sun L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116224
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116224
Possible pharmacological targets and mechanisms of sivelestat in protecting acute lung injury.
Ren J, Deng G, Li R, Jin X, Liu J, Li J, Gao Y, Zhang J, Wang X, Wang G
Computers in biology and medicine 2024 Mar;170:108080
Computers in biology and medicine 2024 Mar;170:108080
SETDB2 interacts with BUBR1 to induce accurate chromosome segregation independently of its histone methyltransferase activity.
Tu Y, Zhang H, Xia J, Zhao Y, Yang R, Feng J, Ma X, Li J
FEBS open bio 2024 Mar;14(3):444-454
FEBS open bio 2024 Mar;14(3):444-454
Qingguang'an-induced autophagy in TFs inhibits scar formation: A follow-up in vivo mechanistic investigation.
Hu R, Wang XJ, Chen S, Huang Y, Yu J
Journal of traditional and complementary medicine 2024 Mar;14(2):173-181
Journal of traditional and complementary medicine 2024 Mar;14(2):173-181
EGLN3 attenuates gastric cancer cell malignant characteristics by inhibiting JMJD8/NF-κB signalling activation independent of hydroxylase activity.
Cai F, Yang X, Ma G, Wang P, Zhang M, Zhang N, Zhang R, Liang H, Nie Y, Dong C, Deng J
British journal of cancer 2024 Mar;130(4):597-612
British journal of cancer 2024 Mar;130(4):597-612
Light-Enhanced Hypoxia-Responsive Gene Editing for Hypoxia-Resistant Photodynamic and Immunotherapy.
Qu S, Ji Y, Fan L, Yan T, Zhu G, Song H, Yang K, Han X
Advanced healthcare materials 2024 Mar;13(7):e2302615
Advanced healthcare materials 2024 Mar;13(7):e2302615
Endothelial cell-derived extracellular vesicles expressing surface VCAM1 promote sepsis-related acute lung injury by targeting and reprogramming monocytes.
Wang L, Tang Y, Tang J, Liu X, Zi S, Li S, Chen H, Liu A, Huang W, Xie J, Liu L, Chao J, Qiu H
Journal of extracellular vesicles 2024 Mar;13(3):e12423
Journal of extracellular vesicles 2024 Mar;13(3):e12423
METTL3-mediated m(6)A modification of SOX4 regulates osteoblast proliferation and differentiation via YTHDF3 recognition.
Feng ZW, Peng B, Wang SH, Zhao DC, Wang YB, Yang A, Zhan HW, Sheng XY, Xu LH, Ren XJ, Yang F, Geng B, Xia YY
Cellular signalling 2024 Mar;115:111038
Cellular signalling 2024 Mar;115:111038
CAR-Aptamers Enable Traceless Enrichment and Monitoring of CAR-Positive Cells and Overcome Tumor Immune Escape.
Zhou H, Abudureheman T, Zheng WW, Yang LT, Zhu JM, Liang AB, Duan CW, Chen K
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(10):e2305566
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(10):e2305566
PM(2.5) induces cardiac defects via AHR-SIRT1-PGC-1α mediated mitochondrial damage.
Chen J, Zhang M, Aniagu S, Jiang Y, Chen T
Environmental toxicology and pharmacology 2024 Mar;106:104393
Environmental toxicology and pharmacology 2024 Mar;106:104393
Artemisinin ameliorates cognitive decline by inhibiting hippocampal neuronal ferroptosis via Nrf2 activation in T2DM mice.
Wang B, Zhu S, Guo M, Ma RD, Tang YL, Nie YX, Gu HF
Molecular medicine (Cambridge, Mass.) 2024 Mar 7;30(1):35
Molecular medicine (Cambridge, Mass.) 2024 Mar 7;30(1):35
Macrophage-derived exosomal HMGB3 regulates silica-induced pulmonary inflammation by promoting M1 macrophage polarization and recruitment.
Qin X, Niu Z, Chen H, Hu Y
Particle and fibre toxicology 2024 Mar 7;21(1):12
Particle and fibre toxicology 2024 Mar 7;21(1):12
Apurinic/apyrimidinic endodeoxyribonuclease 1 (APE1) promotes stress granule formation via YBX1 phosphorylation in ovarian cancer.
Mao S, Xie C, Liu Y, Zhao Y, Li M, Gao H, Xiao Y, Zou Y, Zheng Z, Gao Y, Xie J, Tian B, Wang L, Hua Y, Xu H
Cellular and molecular life sciences : CMLS 2024 Mar 4;81(1):113
Cellular and molecular life sciences : CMLS 2024 Mar 4;81(1):113
Rutaecarpine protects podocytes in diabetic kidney disease by targeting VEGFR2/NLRP3-mediated pyroptosis.
Hu X, Wang J, Jiang L, Liu X, Ge Q, Wang Q, Qi X, Wu Y
International immunopharmacology 2024 Mar 30;130:111790
International immunopharmacology 2024 Mar 30;130:111790
Anti-diabetic mechanism and potential bioactive peptides of casein hydrolysates in STZ/HFD-induced diabetic rats.
Wang C, Luo D, Zheng L, Zhao M
Journal of the science of food and agriculture 2024 Mar 30;104(5):2947-2958
Journal of the science of food and agriculture 2024 Mar 30;104(5):2947-2958
Abscisic acid ameliorates d-galactose -induced aging in mice by modulating AMPK-SIRT1-p53 pathway and intestinal flora.
Zheng Y, Chen X, Ding C, Liu X, Chi L, Zhang S
Heliyon 2024 Mar 30;10(6):e28283
Heliyon 2024 Mar 30;10(6):e28283
TXNIP/NLRP3 aggravates global cerebral ischemia-reperfusion injury-induced cognitive decline in mice.
Yang C, Mo J, Liu Q, Li W, Chen Y, Feng J, Jia J, Liu L, Bai Y, Zhou J
Heliyon 2024 Mar 30;10(6):e27423
Heliyon 2024 Mar 30;10(6):e27423
Progesterone inhibits endometrial cancer growth by inhibiting glutamine metabolism through ASCT2.
Guo J, Fan J, Zhang Y, Li M, Jin Z, Shang Y, Zhang H, Kong Y
Bioscience reports 2024 Mar 29;44(3)
Bioscience reports 2024 Mar 29;44(3)
Human Seminal Extracellular Vesicles Enhance Endometrial Receptivity Through Leukemia Inhibitory Factor.
Wang H, Lin Y, Chen R, Zhu Y, Wang H, Li S, Yu L, Zhang K, Liu Y, Jing T, Sun F
Endocrinology 2024 Mar 29;165(5)
Endocrinology 2024 Mar 29;165(5)
Resveratrol ameliorates glioblastoma inflammatory response by reducing NLRP3 inflammasome activation through inhibition of the JAK2/STAT3 pathway.
Zhang C, Peng Q, Tang Y, Wang C, Wang S, Yu D, Hou S, Wang Y, Zhang L, Lin N
Journal of cancer research and clinical oncology 2024 Mar 28;150(3):168
Journal of cancer research and clinical oncology 2024 Mar 28;150(3):168
Volatile oil of Angelica sinensis Radix improves cognitive function by inhibiting miR-301a-3p targeting Ppp2ca in cerebral ischemia mice.
Zhao J, Luo J, Deng C, Fan Y, Liu N, Cao J, Chen D, Diao Y
Journal of ethnopharmacology 2024 Mar 25;322:117621
Journal of ethnopharmacology 2024 Mar 25;322:117621
Integrating transcriptomics and network pharmacology to reveal the mechanisms of total Rhizoma Coptidis alkaloids against nonalcoholic steatohepatitis.
Li J, Ma Z, Yang Z, Yang M, Li C, Li M, Li X, Chen X, Ma H, Chen W, Ye X, Li X
Journal of ethnopharmacology 2024 Mar 25;322:117600
Journal of ethnopharmacology 2024 Mar 25;322:117600
The mechanism of Chebulae Fructus Immaturus promote diabetic wound healing based on network pharmacology and experimental verification.
Qiu F, Fan S, Diao Y, Liu J, Li B, Li K, Zhang W
Journal of ethnopharmacology 2024 Mar 25;322:117579
Journal of ethnopharmacology 2024 Mar 25;322:117579
Synergistic dual cell therapy for atherosclerosis regression: ROS-responsive Bio-liposomes co-loaded with Geniposide and Emodin.
Li Z, Zhu H, Liu H, Liu D, Liu J, Zhang Y, Qin Z, Xu Y, Peng Y, Ruan L, Li J, He Y, Liu B, Long Y
Journal of nanobiotechnology 2024 Mar 25;22(1):129
Journal of nanobiotechnology 2024 Mar 25;22(1):129
Air-Liquid Interface Microfluidic Monitoring Sensor Platform for Studying Autophagy Regulation after PM2.5 Exposure.
Zheng L, Yang Z, Xue Z, Chen M, Zhang Y, Cai S, Zheng K, Dai B, Liu S, Zhuang S, Sui G, Zhang D
ACS sensors 2024 Mar 22;9(3):1178-1187
ACS sensors 2024 Mar 22;9(3):1178-1187
The Effectiveness of Four Nicotinamide Adenine Dinucleotide (NAD(+)) Precursors in Alleviating the High-Glucose-Induced Damage to Hepatocytes in Megalobrama amblycephala: Evidence in NAD(+) Homeostasis, Sirt1/3 Activation, Redox Defense, Inflammatory Response, Apoptosis, and Glucose Metabolism.
Dong Y, Wang X, Wei L, Liu Z, Chu X, Xiong W, Liu W, Li X
Antioxidants (Basel, Switzerland) 2024 Mar 22;13(4)
Antioxidants (Basel, Switzerland) 2024 Mar 22;13(4)
Melatonin-Derived Carbon Dots with Free Radical Scavenging Property for Effective Periodontitis Treatment via the Nrf2/HO-1 Pathway.
Xin X, Liu J, Liu X, Xin Y, Hou Y, Xiang X, Deng Y, Yang B, Yu W
ACS nano 2024 Mar 19;18(11):8307-8324
ACS nano 2024 Mar 19;18(11):8307-8324
Effects of latroeggtoxin-VI on dopamine and α-synuclein in PC12 cells and the implications for Parkinson's disease.
Yu D, Wang H, Zhai Y, Lei Z, Sun M, Chen S, Yin P, Wang X
Biological research 2024 Mar 16;57(1):9
Biological research 2024 Mar 16;57(1):9
Construction of recombinant fluorescent LSDV for high-throughput screening of antiviral drugs.
Wang J, Ji J, Zhong Y, Meng W, Wan S, Ding X, Chen Z, Wu W, Jia K, Li S
Veterinary research 2024 Mar 16;55(1):33
Veterinary research 2024 Mar 16;55(1):33
Selenomethionine Alleviates Deoxynivalenol-Induced Oxidative Injury in Porcine Intestinal Epithelial Cells Independent of MAPK Pathway Regulation.
Huang Z, Zhong H, Li T, Wang Z, Chen X, Zou T, You J, Chen J
Antioxidants (Basel, Switzerland) 2024 Mar 16;13(3)
Antioxidants (Basel, Switzerland) 2024 Mar 16;13(3)
Glycyrrhizic acid restores the downregulated hepatic ACE2 signaling in the attenuation of mouse steatohepatitis.
Zhou L, Chen S, Wei Y, Sun Y, Yang Y, Lin B, Li Y, Wang C
European journal of pharmacology 2024 Mar 15;967:176365
European journal of pharmacology 2024 Mar 15;967:176365
ICBP90, an epigenetic regulator, induces DKK3 promoter methylation, promotes glioma progression, and reduces sensitivity to cis-platinum.
Cao Q, Wang X, Liu J, Dong Y, Wu X, Mi Y, Liu K, Zhang M, Shi Y, Fan R
Experimental cell research 2024 Mar 15;436(2):113976
Experimental cell research 2024 Mar 15;436(2):113976
CircFOXO3 mediates hypoxia-induced autophagy of endometrial stromal cells in endometriosis.
Zhang L, Liu H, Xiong W, He H, Fu T, Long X, Li X, Liang J, Ding H, Xu Y, Liu Y, Dai X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 15;38(5):e23515
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 15;38(5):e23515
Proteomic and molecular analyses to understand the promotive effect of safranal on soybean growth under salt stress.
Kausar R, Nishiuchi T, Komatsu S
Journal of proteomics 2024 Mar 15;294:105072
Journal of proteomics 2024 Mar 15;294:105072
NOP14 as a Potential Predictor of Adult-Type Diffuse Glioma Prognosis and Immunotherapy, is Related to Cell Migration, Proliferation, and CD8(+)T Cell Infiltration.
Tian QS, Cheng J, Bao ZJ
Frontiers in bioscience (Landmark edition) 2024 Mar 15;29(3):104
Frontiers in bioscience (Landmark edition) 2024 Mar 15;29(3):104
Rh proteins and H(+) transporters involved in ammonia excretion in Amur Ide (Leuciscus waleckii) under high alkali exposure.
Zhao XF, Huang J, Li W, Wang SY, Liang LQ, Zhang LM, Liew HJ, Chang YM
Ecotoxicology and environmental safety 2024 Mar 15;273:116160
Ecotoxicology and environmental safety 2024 Mar 15;273:116160
Rare flavanone-diarylheptanoid hybrids from Typha angustifolia shows anti breast cancer activity via activating TGF-β1/Smad signaling pathway.
Li YP, Liu H, Zhao XC, Tang XL, Shan P, Zhang H
European journal of medicinal chemistry 2024 Mar 15;268:116220
European journal of medicinal chemistry 2024 Mar 15;268:116220
Cancer-associated fibroblast-secreted FGF7 as an ovarian cancer progression promoter.
Feng S, Ding B, Dai Z, Yin H, Ding Y, Liu S, Zhang K, Lin H, Xiao Z, Shen Y
Journal of translational medicine 2024 Mar 15;22(1):280
Journal of translational medicine 2024 Mar 15;22(1):280
Mitochondrial carrier homolog 2 increases malignant phenotype of human gastric epithelial cells and promotes proliferation, invasion, and migration of gastric cancer cells.
Zhang JW, Huang LY, Li YN, Tian Y, Yu J, Wang XF
World journal of gastrointestinal oncology 2024 Mar 15;16(3):991-1005
World journal of gastrointestinal oncology 2024 Mar 15;16(3):991-1005
Epigallocatechin-3-gallate protects sepsis-induced myocardial dysfunction by inhibiting the nuclear factor-κB signaling pathway.
Chen B, Li YF, Fang Z, Cai WY, Tian ZQ, Li D, Wang ZM
Heliyon 2024 Mar 15;10(5):e27163
Heliyon 2024 Mar 15;10(5):e27163
Targeting DEP domain containing 1 in anaplastic thyroid carcinoma: Implications for stemness regulation and malignant phenotype suppression.
Zhu C, Ke S, Li Y, Zhang W, Che Y, Zhang R, Huang P, Xu T
Heliyon 2024 Mar 15;10(5):e27150
Heliyon 2024 Mar 15;10(5):e27150
Glutaredoxin-1 modulates the NF-κB signaling pathway to activate inducible nitric oxide synthase in experimental necrotizing enterocolitis.
Zhang Y, Yan M, Xia Y, Yue Y, Wang S, Hu Y, Lai G, Wu Q, Liu Q, Ding X, Guo C
Molecular therapy. Methods & clinical development 2024 Mar 14;32(1):101214
Molecular therapy. Methods & clinical development 2024 Mar 14;32(1):101214
MRE11A: a novel negative regulator of human DNA mismatch repair.
Du D, Yang Y, Zhang Y, Wang G, Chen L, Guan X, Rasmussen LJ, Liu D
Cellular & molecular biology letters 2024 Mar 14;29(1):37
Cellular & molecular biology letters 2024 Mar 14;29(1):37
Obesity-induced downregulation of miR-192 exacerbates lipopolysaccharide-induced acute lung injury by promoting macrophage activation.
Wu S, Tang W, Liu L, Wei K, Tang Y, Ma J, Li H, Ao Y
Cellular & molecular biology letters 2024 Mar 14;29(1):36
Cellular & molecular biology letters 2024 Mar 14;29(1):36
UCHL1 contributes to insensitivity to endocrine therapy in triple-negative breast cancer by deubiquitinating and stabilizing KLF5.
Li J, Liang Y, Zhou S, Chen J, Wu C
Breast cancer research : BCR 2024 Mar 11;26(1):44
Breast cancer research : BCR 2024 Mar 11;26(1):44
PSMB2 plays an oncogenic role in glioma and correlates to the immune microenvironment.
He W, Zhang Z, Tan Z, Liu X, Wang Z, Xiong B, Shen X, Zhu X
Scientific reports 2024 Mar 11;14(1):5861
Scientific reports 2024 Mar 11;14(1):5861
Solute carrier family 35 member A2 regulates mitophagy through the PI3K/AKT/mTOR axis, promoting the proliferation, migration, and invasion of osteosarcoma cells.
Luo X, Zhang J, Guo C, Jiang N, Zhang F, Jiao Q, Xu K, Yang J, Qu G, Lv XB, Zhang Z
Gene 2024 Mar 10;898:148110
Gene 2024 Mar 10;898:148110
Proteomic analysis of mitochondria associated membranes in renal ischemic reperfusion injury.
Li Y, Wang HB, Cao JL, Zhang WJ, Wang HL, Xu CH, Li KP, Liu Y, Wang JR, Ha HL, Fu SJ, Yang L
Journal of translational medicine 2024 Mar 10;22(1):261
Journal of translational medicine 2024 Mar 10;22(1):261
Melatonin alleviates T-2 toxin-induced oxidative damage, inflammatory response, and apoptosis in piglet spleen and thymus.
Ning C, Xiao W, Liang Z, Wu Y, Fan H, Wang S, Kong X, Wang Y, Wu A, Li Y, Yuan Z, Wu J, Yang C
International immunopharmacology 2024 Mar 10;129:111653
International immunopharmacology 2024 Mar 10;129:111653
Canagliflozin improves fatty acid oxidation and ferroptosis of renal tubular epithelial cells via FOXA1-CPT1A axis in diabetic kidney disease.
Gan T, Wang Q, Song Y, Shao M, Zhao Y, Guo F, Wei F, Fan X, Zhang W, Luo Y, Chen D, Wang S, Qin G
Molecular and cellular endocrinology 2024 Mar 1;582:112139
Molecular and cellular endocrinology 2024 Mar 1;582:112139
f25, a novel synthetic quinoline derivative, inhibits tongue cancer cell invasion and survival by the PPAR pathway in vitro and vivo.
Liu T, Yang L, Li Z, Sun M, Lv N
Chemico-biological interactions 2024 Mar 1;391:110891
Chemico-biological interactions 2024 Mar 1;391:110891
Cannabinoid type 2 receptors play a crucial role in social defeat-induced depression.
Chen XR, Yu R, Chen J, Wang J, Huang HJ, Li HY, Wu GC, Han QQ, Yu J
Journal of affective disorders 2024 Mar 1;348:333-344
Journal of affective disorders 2024 Mar 1;348:333-344
Elucidation of the anti-β-cell dedifferentiation mechanism of a modified Da Chaihu Decoction by an integrative approach of network pharmacology and experimental verification.
Chen H, Guo J, Cai Y, Zhang C, Wei F, Sun H, Cheng C, Liu W, He Z
Journal of ethnopharmacology 2024 Mar 1;321:117481
Journal of ethnopharmacology 2024 Mar 1;321:117481
The circRNA hsa-circ-0013561 regulates head and neck squamous cell carcinoma development via the miR-7-5p/PDK3 axis.
Tian K, Zheng L, Yuan T, Chen X, Chen Q, Xue X, Huang S, He W, Jin M, Zhang Y
Cancer cell international 2024 Mar 1;24(1):91
Cancer cell international 2024 Mar 1;24(1):91
Promoting collateral formation in type 2 diabetes mellitus using ultra-small nanodots with autophagy activation and ROS scavenging.
Wang Y, Li F, Mao L, Liu Y, Chen S, Liu J, Huang K, Chen Q, Wu J, Lu L, Zheng Y, Shen W, Ying T, Dai Y, Shen Y
Journal of nanobiotechnology 2024 Mar 1;22(1):85
Journal of nanobiotechnology 2024 Mar 1;22(1):85
Ssc-miR-429 expression proliles and functions on inducing Leydig cells apoptosis.
Tang Q, Zhang Y, Yue L, Ren H, Pan C
Theriogenology 2024 Mar 1;216:62-68
Theriogenology 2024 Mar 1;216:62-68
Acupuncture alleviates CUMS-induced depression-like behaviors of rats by regulating oxidative stress, neuroinflammation and ferroptosis.
Shen J, Hao C, Yuan S, Chen W, Tong T, Chen Y, Shahzad Aslam M, Yan S, Li J, Zeng J, Liu S, Chen Y, Jiang Y, Li P, Meng X
Brain research 2024 Mar 1;1826:148715
Brain research 2024 Mar 1;1826:148715
RAB22A as a predictor of exosome secretion in the progression and relapse of multiple myeloma.
Fan B, Wang L, Wang J
Aging 2024 Mar 1;16(5):4169-4190
Aging 2024 Mar 1;16(5):4169-4190
TBBPS caused necroptosis and inflammation in hepatocytes by blocking PINK1-PARKIN-mediated mitochondrial autophagy.
Yin Y, Huang M, Xie J, Ou Y, Mai T
Tissue & cell 2024 Jun;88:102382
Tissue & cell 2024 Jun;88:102382
Gastrodin Suppresses the Progression of Atherosclerosis and Vascular Inflammation by Regulating TLR4/NF-κB Pathway.
Dai B, Liu C, Zhang S, Huang M, Yin S
Cell biochemistry and biophysics 2024 Jun;82(2):697-703
Cell biochemistry and biophysics 2024 Jun;82(2):697-703
Alpha-lipoic Acid Prevents Bone Loss in Type 2 Diabetes and Postmenopausal Osteoporosis Coexisting Conditions by Modulating the YAP/Glut4 Pathway.
Xu L, Zhang C, Bao J, Han G, Wang C, Cai Y, Xu G, Sun H, Liu M
Cell biochemistry and biophysics 2024 Jun;82(2):669-685
Cell biochemistry and biophysics 2024 Jun;82(2):669-685
Integrating network pharmacology and experimental models to identify notoginsenoside R1 ameliorates atherosclerosis by inhibiting macrophage NLRP3 inflammasome activation.
Yu J, Hu J, Baldini M, Lei H, Li L, Luo S, Wu J, Liu X, Shan D, Xie Y, Fang H, Yu J
Journal of natural medicines 2024 Jun;78(3):644-654
Journal of natural medicines 2024 Jun;78(3):644-654
Selenite selectively kills lung fibroblasts to treat bleomycin-induced pulmonary fibrosis.
Lin JH, Liu CC, Liu CY, Hsu TW, Yeh YC, How CK, Hsu HS, Hung SC
Redox biology 2024 Jun;72:103148
Redox biology 2024 Jun;72:103148
Disruption of PABPN1 phase separation by SNRPD2 drives colorectal cancer cell proliferation and migration through promoting alternative polyadenylation of CTNNBIP1.
Hu Z, Li M, Chen Y, Chen L, Han Y, Chen C, Lu X, You N, Lou Y, Huang Y, Huo Z, Liu C, Liang C, Liu S, Deng K, Chen L, Chen S, Wan G, Wu X, Fu Y, Xu A
Science China. Life sciences 2024 Jun;67(6):1212-1225
Science China. Life sciences 2024 Jun;67(6):1212-1225
The small nucleolar RNA SNORA51 enhances breast cancer stem cell-like properties via the RPL3/NPM1/c-MYC pathway.
Li S, Jin Z, Song X, Ma J, Peng Z, Yu H, Song J, Zhang Y, Sun X, He M, Yu X, Jin F, Zheng A
Molecular carcinogenesis 2024 Jun;63(6):1117-1132
Molecular carcinogenesis 2024 Jun;63(6):1117-1132
Hsa_circ_0001402 alleviates vascular neointimal hyperplasia through a miR-183-5p-dependent regulation of vascular smooth muscle cell proliferation, migration, and autophagy.
Lin JJ, Chen R, Yang LY, Gong M, Du MY, Mu SQ, Jiang ZA, Li HH, Yang Y, Wang XH, Wang SF, Liu KX, Cao SH, Wang ZY, Zhao AQ, Yang SY, Li C, Sun SG
Journal of advanced research 2024 Jun;60:93-110
Journal of advanced research 2024 Jun;60:93-110
The components of the AhR-molecular chaperone complex differ depending on whether the ligands are toxic or non-toxic.
Narita Y, Tamura A, Hatakeyama S, Uemura S, Miura A, Haga A, Tsuji N, Fujie N, Izumi Y, Sugawara T, Otaka M, Okamoto K, Lu P, Okuda S, Suzuki M, Nagata K, Shimizu H, Itoh H
FEBS letters 2024 Jun;598(12):1478-1490
FEBS letters 2024 Jun;598(12):1478-1490
Combined BRAF and PIM1 inhibitory therapy for papillary thyroid carcinoma based on BRAFV600E regulation of PIM1: Synergistic effect and metabolic mechanisms.
Xu Q, Wang J, Mao Y, Xuan Z, Yang K, Tang X, Zhu X
Neoplasia (New York, N.Y.) 2024 Jun;52:100996
Neoplasia (New York, N.Y.) 2024 Jun;52:100996
Sodium Butyrate Ameliorates Atopic Dermatitis-Induced Inflammation by Inhibiting HDAC3-Mediated STAT1 and NF-κB Pathway.
Hu C, Zeng D, Huang Y, Deng Q, Liu S, Zhou W, Zhou W
Inflammation 2024 Jun;47(3):989-1001
Inflammation 2024 Jun;47(3):989-1001
4-Octyl Itaconate Inhibits Proinflammatory Cytokine Production in Behcet's Uveitis and Experimental Autoimmune Uveitis.
Wang Q, Ye X, Tan S, Jiang Q, Su G, Pan S, Li H, Cao Q, Yang P
Inflammation 2024 Jun;47(3):909-920
Inflammation 2024 Jun;47(3):909-920
Photodynamic therapy inhibits cancer progression and induces ferroptosis and apoptosis by targeting P53/GPX4/SLC7A11 signaling pathways in cholangiocarcinoma.
Yan X, Li Z, Chen H, Yang F, Tian Q, Zhang Y
Photodiagnosis and photodynamic therapy 2024 Jun;47:104104
Photodiagnosis and photodynamic therapy 2024 Jun;47:104104
In vitro modeling of recurrent Dermatofibrosarcoma Protuberans: Assessment of 5-aminolevulinic acid photodynamic therapy efficacy.
Jiang H, He K, Tan J, Zhu D, Yang N, Wang Y, Zhang J, Li X, Ren Y, Lu Y
Photodiagnosis and photodynamic therapy 2024 Jun;47:104093
Photodiagnosis and photodynamic therapy 2024 Jun;47:104093
Reversine inhibits proliferation and induces apoptosis of human osteosarcoma cells through targeting MEK1.
Chen X, Zhong Y, Wang S, Xu S, Chen J, Cheng X, Yang X
Journal of bone oncology 2024 Jun;46:100601
Journal of bone oncology 2024 Jun;46:100601
Antitumor Effect of Apcin on Endometrial Carcinoma via p21-Mediated Cell Cycle Arrest and Apoptosis.
Ni K, Li ZL, Hu ZY, Hong L
Current medical science 2024 Jun;44(3):623-632
Current medical science 2024 Jun;44(3):623-632
Insights into the role of the N6-methyladenosine reader IGF2BP3 in the progression of oral squamous cell carcinoma and its connection to cell-cycle control.
Song D, Dai X, Fu M, Sun Y, Wu X, Zhou Q, Bi W, Sun J, Yang F, Yu Y
Translational oncology 2024 Jun;44:101932
Translational oncology 2024 Jun;44:101932
Licochalcone A alleviates ferroptosis in doxorubicin-induced cardiotoxicity via the PI3K/AKT/MDM2/p53 pathway.
Chen G, Luo S, Guo H, Lin J, Xu S
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jun;397(6):4247-4262
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jun;397(6):4247-4262
Down-regulation of O-GlcNAcylation alleviates insulin signaling pathway impairment following arsenic exposure via suppressing the AMPK/mTOR-autophagy pathway.
Zhang W, Zeng S, Huang J, Tian X, Wu J, Guo L, Liang Y
Toxicology letters 2024 Jun;397:67-78
Toxicology letters 2024 Jun;397:67-78
Pseudorabies virus manipulates mitochondrial tryptophanyl-tRNA synthetase 2 for viral replication.
Li XQ, Cai MP, Wang MY, Shi BW, Yang GY, Wang J, Chu BB, Ming SL
Virologica Sinica 2024 Jun;39(3):403-413
Virologica Sinica 2024 Jun;39(3):403-413
Germacrone alleviates breast cancer-associated osteolysis by inhibiting osteoclastogenesis via inhibition of MAPK/NF-κB signaling pathways.
Lin Z, Yang Y, Liu T, Wu Z, Zhang X, Yang J
Phytotherapy research : PTR 2024 Jun;38(6):2860-2874
Phytotherapy research : PTR 2024 Jun;38(6):2860-2874
Myricanol attenuates sepsis-induced inflammatory responses by nuclear factor erythroid 2-related factor 2 signaling and nuclear factor kappa B/mitogen-activated protein kinase pathway via upregulating Sirtuin 1.
Liu K, Yang L, Wang P, Zhu J, Li F, Peng J, Huang K, Liang M
Inflammopharmacology 2024 Jun;32(3):1887-1901
Inflammopharmacology 2024 Jun;32(3):1887-1901
MDSC-targeting gold nanoparticles enhance PD-1 tumor immunotherapy by inhibiting NLRP3 inflammasomes.
Zhu Y, Chen P, Hu B, Zhong S, Yan K, Wu Y, Li S, Yang Y, Xu Z, Lu Y, Ouyang Y, Bao H, Gu W, Wen L, Zhang Y
Biomaterials 2024 Jun;307:122533
Biomaterials 2024 Jun;307:122533
An ATPase-Mimicking MXene nanozyme pharmacologically breaks the ironclad defense system for ferroptosis cancer therapy.
Wang H, Liu X, Yan X, Du Y, Pu F, Ren J, Qu X
Biomaterials 2024 Jun;307:122523
Biomaterials 2024 Jun;307:122523
Clinical features and molecular landscape of cuproptosis signature-related molecular subtype in gastric cancer.
Chong W, Ren H, Chen H, Xu K, Zhu X, Liu Y, Sang Y, Li H, Liu J, Ye C, Shang L, Jing C, Li L
iMeta 2024 Jun;3(3):e190
iMeta 2024 Jun;3(3):e190
MST1 knockdown inhibits osteoarthritis progression through Parkin-mediated mitophagy and Nrf2/NF-κB signalling pathway.
Ye H, Cai T, Shen Y, Zhao L, Zhang H, Yang J, Li F, Chen J, Shui X
Journal of cellular and molecular medicine 2024 Jun;28(11):e18476
Journal of cellular and molecular medicine 2024 Jun;28(11):e18476
Fibroblast growth factor 21 enhances learning and memory performance in mice by regulating hippocampal L-lactate homeostasis.
Xie J, Yan J, Ji K, Guo Y, Xu S, Shen D, Li C, Gao H, Zhao L
International journal of biological macromolecules 2024 Jun;271(Pt 2):132667
International journal of biological macromolecules 2024 Jun;271(Pt 2):132667
LAGE3 promotes angiogenesis on hepatocellular carcinoma by stabilizing VEGFA mRNA.
Cong Z, Zhao H, Zhang S, You T, Xie Y
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167196
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167196
Total flavonoids of Broussonetia papyrifera alleviate non-alcohol fatty liver disease via regulating Nrf2/AMPK/mTOR signaling pathways.
Wang Q, Wei Y, Wang Y, Yu Z, Qin H, Zhao L, Cheng J, Shen B, Jin M, Feng H
Biochimica et biophysica acta. Molecular and cell biology of lipids 2024 Jun;1869(5):159497
Biochimica et biophysica acta. Molecular and cell biology of lipids 2024 Jun;1869(5):159497
12-O-deacetyl-phomoxanthone A inhibits ovarian tumor growth and metastasis by downregulating PDK4.
Yang C, Xing S, Wei X, Lu J, Zhao G, Ma X, Dai Z, Liang X, Huang W, Liu Y, Jiang X, Zhu D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116736
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116736
Protective role of hydrogen sulfide against diabetic cardiomyopathy by inhibiting pyroptosis and myocardial fibrosis.
Liu M, Zeng C, Zhang Y, Xin Y, Deng S, Hu X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116613
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116613
Synergistic effects of photodynamic therapy and chemotherapy: Activating the intrinsic/extrinsic apoptotic pathway of anoikis for triple-negative breast cancer treatment.
Zhang T, Wang X, Wang D, Lei M, Hu Y, Chen Z, Li Y, Luo Y, Zhang L, Zhu Y
Biomaterials advances 2024 Jun;160:213859
Biomaterials advances 2024 Jun;160:213859
Stanniocalcin 2 Regulates Autophagy and Ferroptosis in Mammary Epithelial Cells of Dairy Cows Through the Mechanistic Target of Rapamycin Complex 1 Pathway.
Li R, Geng H, Tan X, Wang J, Deng L
The Journal of nutrition 2024 Jun;154(6):1790-1802
The Journal of nutrition 2024 Jun;154(6):1790-1802
Lack of vitamin D signalling in mesenchymal progenitors causes fatty infiltration in muscle.
Hosoyama T, Kawai-Takaishi M, Iida H, Yamamoto Y, Nakamichi Y, Watanabe T, Takemura M, Kato S, Uezumi A, Matsui Y
Journal of cachexia, sarcopenia and muscle 2024 Jun;15(3):907-918
Journal of cachexia, sarcopenia and muscle 2024 Jun;15(3):907-918
Enhancement of autophagy can alleviate oxidative stress, inflammation, and apoptosis induced by ammonia stress in yellow catfish Pelteobagrus fulvidraco.
Li X, Wang S, Zhang M, Li M
Fish & shellfish immunology 2024 Jun;149:109582
Fish & shellfish immunology 2024 Jun;149:109582
Fe(3)O(4)-Incorporated Metal-Organic Framework for Chemo/Ferroptosis Synergistic Anti-Tumor via the Enhanced Chemodynamic Therapy.
Xu Y, Wang S, Xiong J, Zheng P, Zhang H, Chen S, Ma Q, Shen J, Velkov T, Dai C, Jiang H
Advanced healthcare materials 2024 Jun;13(14):e2303839
Advanced healthcare materials 2024 Jun;13(14):e2303839
Elimination of radiation-induced senescent cancer cells and stromal cells in vitro by near-infrared photoimmunotherapy.
Suzuki M, Kobayashi H, Hara D, Hanaoka H
Cancer medicine 2024 Jun;13(12):e7381
Cancer medicine 2024 Jun;13(12):e7381
Ginsenoside Rh4 alleviates gastrointestinal mucositis and enhances chemotherapy efficacy through modulating gut microbiota.
Bai X, Deng J, Duan Z, Fu R, Zhu C, Fan D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155577
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155577
Americanin B inhibits pyroptosis in lipopolysaccharide-induced septic encephalopathy mice through targeting NLRP3 protein.
Liu Y, Yao X, Yang Y, Mi Y, Wang Y, Tan S, Fang M, Meng Q, Chen G, Li N, Hou Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155520
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155520
Strictosamide alleviates acute lung injury via regulating T helper 17 cells, regulatory T cells, and gut microbiota.
Wu YH, Zhang QL, Mai SY, Ming GX, Zheng CF, Liang CF, Xue FM, He XN, Li YH
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155490
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155490
Glucose regulates the HMGB1 signaling pathway through SIRT1 in glioma.
Wang Y, Wang S, Wang Y, Wang C, Tang Y, Zhang C, Hou S, Yu D, Lin N
Cellular signalling 2024 Jun;118:111137
Cellular signalling 2024 Jun;118:111137
Mortalin promotes the evolution of androgen-independent prostate cancer through Wnt/β-catenin signaling pathway.
Chang Y, Sui J, Fu Q, Lu Z, Piao Z, Jin T, Zhang M
Cancer cell international 2024 Jun 7;24(1):203
Cancer cell international 2024 Jun 7;24(1):203
Identification of subclusters and prognostic genes based on GLS-associated molecular signature in ulcerative colitis.
Xie Y, Li J, Tao Q, Wu Y, Liu Z, Chen Y, Zeng C
Scientific reports 2024 Jun 7;14(1):13102
Scientific reports 2024 Jun 7;14(1):13102
Prognostic implications of TOR1B expression across cancer types: a focus on basal-like breast cancer and cellular adaptations to hypoxia.
Zhang Y, Cai Z, Chen W, Ye L, Wu X
Journal of cancer research and clinical oncology 2024 Jun 6;150(6):293
Journal of cancer research and clinical oncology 2024 Jun 6;150(6):293
Bile acid metabolism is altered in learning and memory impairment induced by chronic lead exposure.
Liu A, Li Y, Li L, Chen K, Tan M, Zou F, Zhang X, Meng X
Journal of hazardous materials 2024 Jun 5;471:134360
Journal of hazardous materials 2024 Jun 5;471:134360
FBP1 orchestrates keratinocyte proliferation/differentiation and suppresses psoriasis through metabolic control of histone acetylation.
Zhang P, Yang J, Liu X, Huang C, Tao Y, Shen P, Bai Z, Xiao C, Zhou L, Li G, Zhang L, Zhou W, Gao Y
Cell death & disease 2024 Jun 4;15(6):392
Cell death & disease 2024 Jun 4;15(6):392
Integrating network pharmacology and experimental validation reveals therapeutic effects of D-mannose on NAFLD through mTOR suppression.
Zhang S, Gao YF, Zhang K, Deng GR, He GX, Gao PP, Yu YK, Yuan Y, Xing SJ, Zhao N, Zhang H, Di-Wu YC, Liu YH, Sui BD, Li Z, Ma J, Zheng CX
Biochemical and biophysical research communications 2024 Jun 30;715:149999
Biochemical and biophysical research communications 2024 Jun 30;715:149999
Proteomics coupled transcriptomics reveals Slc34a1 and Slc34a3 downregulation as potential features of nephrotoxin-induced acute kidney injury.
Zhang J, Che T, Wang L, Sun W, Zhao J, Chen J, Liu Y, Pu Q, Zhang Y, Li J, Li Z, Zhu Z, Fu Q, Wang X, Yuan J
Journal of proteomics 2024 Jun 30;302:105203
Journal of proteomics 2024 Jun 30;302:105203
Defective interferon signaling in the circulating monocytes of type 2 diabetic mice.
Omodaka S, Kato Y, Sato Y, Falcone-Juengert J, Zhang H, Kanoke A, Eckalbar WL, Endo H, Hsieh CL, Aran D, Liu J
bioRxiv : the preprint server for biology 2024 Jun 3;
bioRxiv : the preprint server for biology 2024 Jun 3;
Cordycepin Enhances the Therapeutic Efficacy of Doxorubicin in Treating Triple-Negative Breast Cancer.
Huang H, Li X, Wu W, Liu C, Shao Y, Wu X, Fu J
International journal of molecular sciences 2024 Jun 27;25(13)
International journal of molecular sciences 2024 Jun 27;25(13)
Nicotinate-curcumin improves NASH by inhibiting the AKR1B10/ACCα-mediated triglyceride synthesis.
Lin XL, Zeng YL, Ning J, Cao Z, Bu LL, Liao WJ, Zhang ZM, Zhao TJ, Fu RG, Yang XF, Gong YZ, Lin LM, Cao DL, Zhang CP, Liao DF, Li YM, Zeng JG
Lipids in health and disease 2024 Jun 27;23(1):201
Lipids in health and disease 2024 Jun 27;23(1):201
Activation of aryl hydrocarbon receptor (AhR) alleviates depressive-like behaviors in LPS-induced mice.
Wang MY, Li JM, Wu YL, Zhang Y, Hu T, Su WJ, Feng JF, Jiang CL
Sheng li xue bao : [Acta physiologica Sinica] 2024 Jun 25;76(3):353-364
Sheng li xue bao : [Acta physiologica Sinica] 2024 Jun 25;76(3):353-364
A drug repurposing study identifies novel FOXM1 inhibitors with in vitro activity against breast cancer cells.
Abusharkh KAN, Comert Onder F, Çınar V, Hamurcu Z, Ozpolat B, Ay M
Medical oncology (Northwood, London, England) 2024 Jun 25;41(8):188
Medical oncology (Northwood, London, England) 2024 Jun 25;41(8):188
Expression Regulation of Gluconeogenesis Related Genes in Ovine Skeletal Muscle Cells.
Pang Y, Hu S, Wen B, Wu D, Song F, Yin J, Wu J
Frontiers in bioscience (Landmark edition) 2024 Jun 25;29(6):237
Frontiers in bioscience (Landmark edition) 2024 Jun 25;29(6):237
Expression of VISTA regulated via IFN-γ governs endogenous T-cell function and exhibits correlation with the efficacy of CD19 CAR-T cell treated B-malignant mice.
Tang D, Zhao L, Yan F, Ren C, Xu K, Zhao K
Journal for immunotherapy of cancer 2024 Jun 25;12(6)
Journal for immunotherapy of cancer 2024 Jun 25;12(6)
Cytoplasmic TP53INP2 acts as an apoptosis partner in TRAIL treatment: the synergistic effect of TRAIL with venetoclax in TP53INP2-positive acute myeloid leukemia.
Ren J, Huang J, Yang Z, Sun M, Yang J, Lin C, Jin F, Liu Y, Tang L, Hu J, Wei X, Chen X, Yuan Z, Yang Z, Chen Y, Zhang L
Journal of experimental & clinical cancer research : CR 2024 Jun 22;43(1):176
Journal of experimental & clinical cancer research : CR 2024 Jun 22;43(1):176
Renal inflammation combined with renal function reserve reduction accelerate kidney aging via pentose phosphate pathway.
Han B, Zhang Y, Liu C, Ji P, Xing Z, Geng X, Chi K, Gong M, Li Y, Zhang Y, Fu Z, Hong Q, Cai G, Chen X, Sun X
iScience 2024 Jun 21;27(6):110045
iScience 2024 Jun 21;27(6):110045
Inhibiting Pink1/Parkin-mediated mitophagy enhances the anticancer effects of quercetin in hepatocellular carcinomaf.
Chen F
Biochemical and biophysical research communications 2024 Jun 18;712-713:149899
Biochemical and biophysical research communications 2024 Jun 18;712-713:149899
Low PDE4A expression promoted the progression of ovarian cancer by inducing Snail nuclear translocation.
Wang J, Gu Q, Liu Y, Huang X, Zhang J, Liu B, Li R, Linghu H
Experimental cell research 2024 Jun 15;439(2):114100
Experimental cell research 2024 Jun 15;439(2):114100
Asprosin promotes vascular inflammation via TLR4-NFκB-mediated NLRP3 inflammasome activation in hypertension.
Ge R, Chen JL, Zheng F, Yin SM, Dai M, Wang YM, Chen Q, Li YH, Zhu GQ, Chen AD
Heliyon 2024 Jun 15;10(11):e31659
Heliyon 2024 Jun 15;10(11):e31659
Pseudolaric Acid B Targets CD147 to Selectively Kill Acute Myeloid Leukemia Cells.
Zou S, Parfenova E, Vrdoljak N, Minden MD, Spagnuolo PA
International journal of molecular sciences 2024 Jun 13;25(12)
International journal of molecular sciences 2024 Jun 13;25(12)
ZFHX3 acts as a tumor suppressor in prostate cancer by targeting FTO-mediated m(6)A demethylation.
Hu Q, Yin J, Zhao S, Wang Y, Shi R, Yan K, Huang S
Cell death discovery 2024 Jun 13;10(1):284
Cell death discovery 2024 Jun 13;10(1):284
Yunvjian decoction mitigates hyperglycemia in rats induced by a high-fat diet and streptozotocin via reducing oxidative stress in pancreatic beta cells.
Lv J, Su M, Wang Y, Yang J, Liang Y, Chen L, Lei L
Journal of ethnopharmacology 2024 Jun 12;327:118045
Journal of ethnopharmacology 2024 Jun 12;327:118045
Integration of Proteomic and Metabolomic Data Reveals the Lipid Metabolism Disorder in the Liver of Rats Exposed to Simulated Microgravity.
Ru M, He J, Bai Y, Zhang K, Shi Q, Gao F, Wang Y, Li B, Shen L
Biomolecules 2024 Jun 12;14(6)
Biomolecules 2024 Jun 12;14(6)
Inefficacy of anti-VEGF therapy reflected in VEGF-mediated photoreceptor degeneration.
Xu X, Han N, Zhao F, Fan R, Guo Q, Han X, Liu Y, Luo G
Molecular therapy. Nucleic acids 2024 Jun 11;35(2):102176
Molecular therapy. Nucleic acids 2024 Jun 11;35(2):102176
Lycorine attenuated proliferation and induced apoptosis on imatinib-resistant K562 cell by inhibiting autophagy.
Bai J, Feng Z, Chen Y, Li Y, Zhang L, Li L
Discover oncology 2024 Jun 10;15(1):217
Discover oncology 2024 Jun 10;15(1):217
Sodium-glucose cotransporter 1 promotes the biofunctions of perivascular preadipocytes mediated by Akt/mTOR/p70S6K signaling pathway.
Liu Z, Wang J, Tian P, Liu Y, Xing L, Fu C, Huang X, Liu P
American journal of physiology. Cell physiology 2024 Jun 1;326(6):C1611-C1624
American journal of physiology. Cell physiology 2024 Jun 1;326(6):C1611-C1624
Docosahexaenoic Acid Coordinating with Sodium Selenite Promotes Paraptosis in Colorectal Cancer Cells by Disrupting the Redox Homeostasis and Activating the MAPK Pathway.
Zhao S, Meng Y, Cai W, Luo Q, Gao H, Shen Q, Shi D
Nutrients 2024 Jun 1;16(11)
Nutrients 2024 Jun 1;16(11)
Examining the molecular mechanisms of topiramate in alleviating insulin resistance: A study on C2C12 myocytes and 3T3L-1 adipocytes.
Yang YH, Fan XX, Ye L, Huang WJ, Ko CY
Endocrine 2024 Jul;85(1):168-180
Endocrine 2024 Jul;85(1):168-180
A Novel lncRNA lncRNA-4045 Promotes the Progression of Hepatocellular Carcinoma by Affecting the Expression of AKR1B10.
Tan C, Zeng X, Guo X, Mo M, Ma X, Liu B, Liu S, Zeng X, Huang D, Qiu X
Digestive diseases and sciences 2024 Jul;69(7):2502-2521
Digestive diseases and sciences 2024 Jul;69(7):2502-2521
Postbiotics Prepared Using Lactobacillus reuteri Ameliorates Ethanol-Induced Liver Injury by Regulating the FXR/SHP/SREBP-1c Axis.
Liu C, Cai T, Cheng Y, Bai J, Li M, Gu B, Huang M, Fu W
Molecular nutrition & food research 2024 Jul;68(14):e2300927
Molecular nutrition & food research 2024 Jul;68(14):e2300927
Hypoxia-mediated attenuation of EGLN2 inhibition of the NF-κB signaling pathway leads to the formation of a loop between HIF-1α and MUC1-C promoting chemoresistance in bladder cancer.
Qing L, Li Q, Yang Y, Xu W, Wang Y, Li R, You C, Dong Z
Molecular carcinogenesis 2024 Jul;63(7):1303-1318
Molecular carcinogenesis 2024 Jul;63(7):1303-1318
HHLA2 promotes hepatoma cell proliferation, migration, and invasion via SPP1/PI3K/AKT signaling pathway.
Wang J, Yang K, Yang X, Jin T, Tian Y, Dai C, Xu F
Molecular carcinogenesis 2024 Jul;63(7):1275-1287
Molecular carcinogenesis 2024 Jul;63(7):1275-1287
Circadian disruption reduces MUC4 expression via the clock molecule BMAL1 during dry eye development.
Zeng H, Yang X, Liao K, Zuo X, Liang L, He D, Ju R, Wang B, Yuan J
Experimental & molecular medicine 2024 Jul;56(7):1655-1666
Experimental & molecular medicine 2024 Jul;56(7):1655-1666
Reduced Malignancy of Super Methotrexate-resistant Osteosarcoma Cells With Dihydrofolate Reductase Amplification Despite Paradoxical Gain of Oncogenic PI3K/AKT/mTOR and c-MYC expression.
Aoki Y, Kubota Y, Masaki N, Obara K, Tome Y, Bouvet M, Nishida K, Hoffman RM
Anticancer research 2024 Jul;44(7):2787-2792
Anticancer research 2024 Jul;44(7):2787-2792
Major Facilitator Superfamily Domain Containing 12 Is Overexpressed in Lung Cancer and Exhibits an Oncogenic Role in Lung Adenocarcinoma Cells.
Zhao W, Hu X, Chen Z, Li X
DNA and cell biology 2024 Jul;43(7):331-340
DNA and cell biology 2024 Jul;43(7):331-340
p97 inhibits integrated stress response-induced neuronal apoptosis after subarachnoid hemorrhage in mice by enhancing proteasome function.
Cheng W, Wei B, Liu W, Jin L, Guo S, Ding M, Liu Y, Fan H, Li R, Zhang X, He X, Li X, Duan C
Experimental neurology 2024 Jul;377:114778
Experimental neurology 2024 Jul;377:114778
A crucial role of adenosine deaminase in regulating gluconeogenesis in mice.
Ding Z, Ge W, Xu X, Xu X, Sun Q, Xu X, Zhang J
The Journal of biological chemistry 2024 Jul;300(7):107425
The Journal of biological chemistry 2024 Jul;300(7):107425
Mitochondria-targeted ruthenium complexes can be generated in vitro and in living cells to target triple-negative breast cancer cells by autophagy inhibition.
Zhang GD, Wang MM, Su Y, Fang H, Xue XL, Liu HK, Su Z
Journal of inorganic biochemistry 2024 Jul;256:112574
Journal of inorganic biochemistry 2024 Jul;256:112574
Calcitriol attenuates lipopolysaccharide-induced neuroinflammation and depressive-like behaviors by suppressing the P2X7R/NLRP3/caspase-1 pathway.
Wang C, Cui C, Xie X, Chen B, Feng L, Jiang P
Psychopharmacology 2024 Jul;241(7):1329-1343
Psychopharmacology 2024 Jul;241(7):1329-1343
Isoprenylcysteine carboxyl methyltransferase (ICMT) promotes invadopodia formation and metastasis in cancer cells.
Borini Etichetti C, Arel Zalazar E, Di Benedetto C, Cocordano N, Valente S, Bicciato S, Menacho-Márquez M, Larocca MC, Girardini J
Biochimie 2024 Jul;222:28-36
Biochimie 2024 Jul;222:28-36
Grifolin Induces Cell Death of Human Lung Cancer A549 Cell Line via Inhibiting KRAS-Mediated Multiple Signaling Pathways.
Zhao XC, Ma RF, Liu H, Shan P, Bao J, Zhang H
Chemistry & biodiversity 2024 Jul;21(7):e202400792
Chemistry & biodiversity 2024 Jul;21(7):e202400792
SH-Alb inhibits phenotype remodeling of pro-fibrotic macrophage to attenuate liver fibrosis through SIRT3-SOD2 axis.
Wu N, Ma S, Ding H, Cao H, Liu T, Tian M, Liu Q, Bian H, Yu Z, Liu C, Wang L, Feng Y, Wu H, Qi J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jul;176:116919
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jul;176:116919
GRP78 Downregulation in Keratinocytes Promotes Skin Inflammation through the Recruitment and Activation of CCR6(+) IL-17A-Producing γδ T Cells.
Zhao L, Li J, Jiang B, Yang J, Lan J, Li D, Wen J, Xia Y, Nie W, Wang Z, Lv Y, Zeng F, Li Y, Shen G, Lei P, Tao J
The Journal of investigative dermatology 2024 Jul;144(7):1557-1567.e11
The Journal of investigative dermatology 2024 Jul;144(7):1557-1567.e11
HELQ deficiency impairs the induction of primordial germ cell-like cells.
Wan C, Huang Y, Xue X, Chang G, Wang M, Zhao XY, Luo F, Tang ZZ
FEBS open bio 2024 Jul;14(7):1087-1100
FEBS open bio 2024 Jul;14(7):1087-1100
The dual role of 20(S)-protopanaxadiol in alleviating pulmonary fibrosis through the gut-lung axis.
Ruan Y, Ren G, Wang M, Lv W, Shimizu K, Zhang C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155699
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155699
Celastrol mediates CAV1 to attenuate pro-tumorigenic effects of senescent cells.
Zhang S, Zhu N, Shi YN, Zeng Q, Zhang CJ, Li HF, Qin L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155614
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155614
IRAK1 deficiency potentiates the efficacy of radiotherapy in repressing cervical cancer development.
Chen W, Xie X, Liu C, Liao J, Wei Y, Wu R, Hong J
Cellular signalling 2024 Jul;119:111192
Cellular signalling 2024 Jul;119:111192
CircUGGT2 facilitates progression and cisplatin resistance of bladder cancer through nonhomologous end-joining pathway.
Lyu F, Huang S, Yan Z, He Q, Liu C, Cheng L, Cong Y, Chen K, Song Y, Xing Y
Cellular signalling 2024 Jul;119:111164
Cellular signalling 2024 Jul;119:111164
CD44v5 domain regulates crosstalk between TNBC cells and tumor-associated macrophages by enhancing the IL-4R/STAT3 axis.
Dai Y, Ji Z, Liang H, Jiang M, Wang L, Bao X, Liu J, Liu M, Yang C
Cancer science 2024 Jul;115(7):2235-2253
Cancer science 2024 Jul;115(7):2235-2253
Hypoxia-inducible factor-1α attenuates renal podocyte injury in male rats in a simulated high-altitude environment by upregulating Krüppel-like factor 4 expression.
Xiaoshan Z, Huan C, Zhilin G, Liwen M, Yan Z, Yue C
Experimental physiology 2024 Jul;109(7):1188-1198
Experimental physiology 2024 Jul;109(7):1188-1198
Development of an integrated and project-based laboratory course in upper-level biochemistry and molecular biology.
Liu Y, Tu S, Hu X, Xiong X, Pan Z, Liu Z, Zhu W, Luo D, Cui X, Huang C, Xie C
Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology 2024 Jul-Aug;52(4):411-425
Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology 2024 Jul-Aug;52(4):411-425
Expression of PD-L1 Is Increased by Methionine Restriction Using Recombinant Methioninase in Human Colorectal Cancer Cells.
Mizuta K, Kang BM, Han Q, Kubota Y, Morinaga S, Sato M, Bouvet M, Tome Y, Nishida K, Hoffman RM
Cancer genomics & proteomics 2024 Jul-Aug;21(4):395-398
Cancer genomics & proteomics 2024 Jul-Aug;21(4):395-398
The impact of Nrf2 knockout on the neuroprotective effects of dexmedetomidine in a mice model of cognitive impairment.
Chen L, Yue Z, Liu Z, Liu H, Zhang J, Zhang F, Hu T, Fu J
Behavioural brain research 2024 Jul 9;469:115006
Behavioural brain research 2024 Jul 9;469:115006
Emodin alleviates intestinal ischemia-reperfusion injury through antioxidant stress, anti-inflammatory responses and anti-apoptosis effects via Akt-mediated HO-1 upregulation.
Liu Y, Ji T, Jiang H, Chen M, Liu W, Zhang Z, He X
Journal of inflammation (London, England) 2024 Jul 9;21(1):25
Journal of inflammation (London, England) 2024 Jul 9;21(1):25
HOXC4 promotes proliferation of pancreatic cancer cells by increasing LDHA-mediated glycolysis.
Zhang H, Han B, Tian S, Gong Y, Chen L, Liu L
Aging 2024 Jul 9;16(13):11103-11116
Aging 2024 Jul 9;16(13):11103-11116
Targeting the PI3K/AKT/mTOR pathway offer a promising therapeutic strategy for cholangiocarcinoma patients with high doublecortin-like kinase 1 expression.
Liang Z, Ge Y, Li J, Bai Y, Xiao Z, Yan R, An G, Zhang D
Journal of cancer research and clinical oncology 2024 Jul 9;150(7):342
Journal of cancer research and clinical oncology 2024 Jul 9;150(7):342
Acetyl-11-keto-β-boswellic acid restrains the progression of synovitis in osteoarthritis via the Nrf2/HO-1 pathway.
Zhou J, Li X, Han Z, Qian Y, Bai L, Han Q, Gao M, Xue Y, Geng D, Yang X, Hao Y
Acta biochimica et biophysica Sinica 2024 Jul 8;56(11):1644-1658
Acta biochimica et biophysica Sinica 2024 Jul 8;56(11):1644-1658
Biomimetic NO Scavenging Hyaluronic Acid Nanoparticles Enable Targeted Delivery of MTX and Integrated Management of Rheumatoid Arthritis.
Liu Y, Luo H, Liu B, Zhou T, Zhang Z, Liu Z
Biomacromolecules 2024 Jul 8;25(7):4557-4568
Biomacromolecules 2024 Jul 8;25(7):4557-4568
FERMT1 suppression induces anti-tumor effects and reduces stemness in glioma cancer cells.
Pan Z, Ke C, Zheng H, Guo X, Gao W, Huang X, Chen C, Xiong Y, Zheng S, Zheng F, Hu W
Journal of cancer research and clinical oncology 2024 Jul 8;150(7):338
Journal of cancer research and clinical oncology 2024 Jul 8;150(7):338
Peptide PDRPS6 attenuates myocardial ischemia injury by improving mitochondrial function.
Feng M, Zhang L, Yin A, Zhang H, Wu X, Qian L
European journal of pharmacology 2024 Jul 5;974:176570
European journal of pharmacology 2024 Jul 5;974:176570
Dulaglutide restores endothelial progenitor cell levels in diabetic mice and mitigates high glucose-induced endothelial injury through SIRT1-mediated mitochondrial fission.
Mei X, Li Y, Wu J, Liao L, Lu D, Qiu P, Yang HL, Tang MW, Liang XY, Liu D
Biochemical and biophysical research communications 2024 Jul 5;716:150002
Biochemical and biophysical research communications 2024 Jul 5;716:150002
Targeted delivery of CEBPA-saRNA for the treatment of pancreatic ductal adenocarcinoma by transferrin receptor aptamer decorated tetrahedral framework nucleic acid.
Wang L, Yao Q, Guo X, Wang B, Si J, Wang X, Jing S, Yan M, Shi Y, Song G, Shen X, Guan J, Zhao Y, Zhu C
Journal of nanobiotechnology 2024 Jul 4;22(1):392
Journal of nanobiotechnology 2024 Jul 4;22(1):392
A black phosphorus nanosheet-based RNA delivery system for prostate cancer therapy by increasing the expression level of tumor suppressor gene PTEN via CeRNA mechanism.
Su S, Liu L, Fu Q, Ma M, Yang N, Pan T, Geng S, Yu XF, Zhu J
Journal of nanobiotechnology 2024 Jul 4;22(1):391
Journal of nanobiotechnology 2024 Jul 4;22(1):391
Paeoniflorin Promotes Ovarian Development in Mice by Activating Mitophagy and Preventing Oxidative Stress.
Xi H, Wang Z, Li M, Duan X, Li Y
International journal of molecular sciences 2024 Jul 30;25(15)
International journal of molecular sciences 2024 Jul 30;25(15)
Metabolic reprogramming and heterogeneity during the decidualization process of endometrial stromal cells.
Jia Z, Wei Y, Zhang Y, Song K, Yuan J
Cell communication and signaling : CCS 2024 Jul 30;22(1):385
Cell communication and signaling : CCS 2024 Jul 30;22(1):385
Lactylation of histone by BRD4 regulates astrocyte polarization after experimental subarachnoid hemorrhage.
Zhang F, Zhou J, Lu P, Zhang X, Yang L, Wu J, Zhang L, Zhang L, Pang J, Xie H, Xie B, Jiang Y, Peng J
Journal of neuroinflammation 2024 Jul 30;21(1):186
Journal of neuroinflammation 2024 Jul 30;21(1):186
Andrographolide sulfonate downregulation of TLR3-TRIF and amelioration of airway inflammation caused by respiratory syncytial virus infection.
Zhou N, Che S, Liu J, Jiang Z, Ren L, Liu Y, Liu E, Xie J
Journal of thoracic disease 2024 Jul 30;16(7):4607-4618
Journal of thoracic disease 2024 Jul 30;16(7):4607-4618
The Coptidis Rhizoma and Bovis Calculus herb pair attenuates NASH and inhibits the NLRP3 inflammasome activation.
Xu T, Chen J, Shao Q, Ji J, Wang Q, Ma C, Wang X, Cheng F
Heliyon 2024 Jul 30;10(14):e34718
Heliyon 2024 Jul 30;10(14):e34718
AP-1 inhibitor induces ferroptosis via the PI3K/AKT pathway in multiple myeloma cells.
Tang S, Liu J, Li F, Yan Y, Long X, Fu Y
Heliyon 2024 Jul 30;10(14):e34397
Heliyon 2024 Jul 30;10(14):e34397
Pathological polarizations from microglia to astrocyte contributes to spatial memory deficit in methamphetamine abstinence mice.
Mai Y, Cheng Z, Wang Z, Hu T, Zhang Y, Yuan X, Xu X, Fan Y, Ge F, Shi P, Wang J, Yang X, Guan X
Cerebral cortex (New York, N.Y. : 1991) 2024 Jul 3;34(7)
Cerebral cortex (New York, N.Y. : 1991) 2024 Jul 3;34(7)
USP9X regulates the proliferation, survival, migration and invasion of gastric cancer cells by stabilizing MTH1.
Xu W, Zhang Y, Su Y, Li L, Yang X, Wang L, Gao H
BMC gastroenterology 2024 Jul 29;24(1):239
BMC gastroenterology 2024 Jul 29;24(1):239
Deciphering the Effects of the PYCR Family on Cell Function, Prognostic Value, Immune Infiltration in ccRCC and Pan-Cancer.
Chen H, Chen Q, Chen J, Mao Y, Duan L, Ye D, Cheng W, Chen J, Gao X, Lin R, Lin W, Zhang M, Qi Y
International journal of molecular sciences 2024 Jul 25;25(15)
International journal of molecular sciences 2024 Jul 25;25(15)
Bacillus coagulans restores pathogen-induced intestinal dysfunction via acetate-FFAR2-NF-κB-MLCK-MLC axis in Apostichopus japonicus.
Song M, Zhang S, Zhang Z, Guo L, Liang W, Li C, Wang Z
mSystems 2024 Jul 23;9(7):e0060224
mSystems 2024 Jul 23;9(7):e0060224
Lipid-associated macrophages reshape BAT cell identity in obesity.
Sciarretta F, Ninni A, Zaccaria F, Chiurchiù V, Bertola A, Karlinsey K, Jia W, Ceci V, Di Biagio C, Xu Z, Gaudioso F, Tortolici F, Tiberi M, Zhang J, Carotti S, Boudina S, Grumati P, Zhou B, Brestoff JR, Ivanov S, Aquilano K, Lettieri-Barbato D
Cell reports 2024 Jul 23;43(7):114447
Cell reports 2024 Jul 23;43(7):114447
Molecular characterization and clinical relevance of metabolic signature subtypes in gastric cancer.
Chen H, Jing C, Shang L, Zhu X, Zhang R, Liu Y, Wang M, Xu K, Ma T, Jing H, Wang Z, Li X, Chong W, Li L
Cell reports 2024 Jul 23;43(7):114424
Cell reports 2024 Jul 23;43(7):114424
[ZIF-8@Pt Nanozyme Used for Scavenging Reactive Oxygen Species in the Treatment of Rheumatoid Arthritis].
Lei X, Qiu L, DU F
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 2024 Jul 20;55(4):826-837
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 2024 Jul 20;55(4):826-837
Activation of PPAR-α attenuates myocardial ischemia/reperfusion injury by inhibiting ferroptosis and mitochondrial injury via upregulating 14-3-3η.
Hu T, Yu WP, Wang XQ, Wang ZY, Xu ZQ, Hu FJ, Liu JC, Yu F, Wang LJ
Scientific reports 2024 Jul 2;14(1):15246
Scientific reports 2024 Jul 2;14(1):15246
Type III adenylyl cyclase is essential for follicular development in female mice and their reproductive lifespan.
Zheng B, Hu X, Hu Y, Dong S, Xiao X, Qi H, Wang Y, Wang W, Wang Z
iScience 2024 Jul 19;27(7):110293
iScience 2024 Jul 19;27(7):110293
Mitochondrial miR-12294-5p-Regulated Copper Exposure-Caused Mitochondrial-Dependent Ferroptosis by Targeted Inhibition of CISD1 in Chicken Hepatocytes.
Zhong G, Wang M, Sun B, Ma F, Yu W, Hu L, Liao J, Tang Z
Journal of agricultural and food chemistry 2024 Jul 17;72(28):15948-15958
Journal of agricultural and food chemistry 2024 Jul 17;72(28):15948-15958
Morphine timing-dependent modulation of TRPV1 phosphorylation correlates with differential morphine effects on myocardial ischemia/reperfusion injury.
Wang XM, Li XX, Jiang B, Wang TQ, Guo Z
European journal of pharmacology 2024 Jul 15;975:176648
European journal of pharmacology 2024 Jul 15;975:176648
Bmal1 regulates female reproduction in mice via the hypothalamic-pituitary-ovarian axis.
Zhang A, Li S, Huang L, Jiang Y, Chen Y, Zhu S, Xiong F, Luo Z, Ou M, Ying J, Wang S, Mu D, Qu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23744
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23744
Diquat causes mouse testis injury through inducing heme oxygenase-1-mediated ferroptosis in spermatogonia.
Cheng J, Yang L, Zhang Z, Xu D, Hua R, Chen H, Li X, Duan J, Li Q
Ecotoxicology and environmental safety 2024 Jul 15;280:116562
Ecotoxicology and environmental safety 2024 Jul 15;280:116562
Glutamate rescues heat stress-induced apoptosis of Sertoli cells by enhancing the activity of antioxidant enzymes and activating the Trx1-Akt pathway in vitro.
Cai XQ, Yang H, Liang BQ, Deng CC, Xue HY, Zhang JJ, Wang XZ
Theriogenology 2024 Jul 15;223:1-10
Theriogenology 2024 Jul 15;223:1-10
Discovery of 5-(Piperidin-4-yl)-1,2,4-oxadiazole Derivatives as a New Class of Human Caseinolytic Protease P Agonists for the Treatment of Hepatocellular Carcinoma.
Liu S, Sui J, Luo B, Zhang J, Xiang X, Yang T, Luo Y, Liu J
Journal of medicinal chemistry 2024 Jul 11;67(13):10622-10642
Journal of medicinal chemistry 2024 Jul 11;67(13):10622-10642
Melanoma-Derived Extracellular Vesicles Induce CD36-Mediated Pre-Metastatic Niche.
Suman S, Nevala WK, Leontovich AA, Ward C, Jakub JW, Kim Y, Geng L, Stueven NA, Atherton CL, Moore RM, Schimke JM, Lucien-Matteoni F, McLaughlin SA, Markovic SN
Biomolecules 2024 Jul 11;14(7)
Biomolecules 2024 Jul 11;14(7)
CD24 promotes metastasis and chemoresistance by directly targeting Arf6-ERK pathway in esophageal squamous cell carcinoma.
Hong P, Xu T, Xu J, Chen W, Hu H, Chen J, Li L, Zheng C, Li B, Liu J, Dai W, Li E, Zhang F, Xu W
Cancer letters 2024 Jul 10;594:216994
Cancer letters 2024 Jul 10;594:216994
NAD(+) supplementation improves mitochondrial functions and normalizes glaucomatous trabecular meshwork features.
Liu Y, Bu Q, Hu D, Chen C, Zhu J, Zhou Q, Li Z, Pan X
Experimental cell research 2024 Jul 1;440(1):114137
Experimental cell research 2024 Jul 1;440(1):114137
Pramipexole improves depression-like behavior in diabetes mellitus with depression rats by inhibiting NLRP3 inflammasome-mediated neuroinflammation and preventing impaired neuroplasticity.
Li P, Wang T, Guo H, Liu Y, Zhao H, Ren T, Tang Y, Wang Y, Zou M
Journal of affective disorders 2024 Jul 1;356:586-596
Journal of affective disorders 2024 Jul 1;356:586-596
Melatonin improves synapse development by PI3K/Akt signaling in a mouse model of autism spectrum disorder.
Wang L, Xu M, Wang Y, Wang F, Deng J, Wang X, Zhao Y, Liao A, Yang F, Wang S, Li Y
Neural regeneration research 2024 Jul 1;19(7):1618-1624
Neural regeneration research 2024 Jul 1;19(7):1618-1624
Pleiotropic effects of nitric oxide sustained-release system for peripheral nerve repair.
Huo Y, Cheng Y, Dong X, Cheng Q, Liang X, Duan P, Yu Y, Yan L, Qiu T, Pan Z, Dai H
Acta biomaterialia 2024 Jul 1;182:28-41
Acta biomaterialia 2024 Jul 1;182:28-41
Disorder of neuroplasticity aggravates cognitive impairment via neuroinflammation associated with intestinal flora dysbiosis in chronic heart failure.
Chen J, Wei X, Wu X, Zhang Q, Xia G, Xia H, Shang H, Lin S
Aging 2024 Jul 1;16(13):10882-10904
Aging 2024 Jul 1;16(13):10882-10904
Mitofusin2 Ameliorated Endoplasmic Reticulum Stress and Mitochondrial Reactive Oxygen Species Through Maintaining Mitochondria-Associated Endoplasmic Reticulum Membrane Integrity in Cisplatin-Induced Acute Kidney Injury.
Liu YT, Zhang H, Duan SB, Wang JW, Chen H, Zhan M, Zhang W, Li AM, Liu Y, Yang Y, Yang S
Antioxidants & redox signaling 2024 Jan;40(1-3):16-39
Antioxidants & redox signaling 2024 Jan;40(1-3):16-39
Activation of immune evasion machinery is a part of the process of malignant transformation of human cells.
Abooali M, Yasinska IM, Schlichtner S, Ruggiero S, Berger SM, Cholewa D, Milošević M, Bartenstein A, Fasler-Kan E, Sumbayev VV
Translational oncology 2024 Jan;39:101805
Translational oncology 2024 Jan;39:101805
miRNA-211-5p inhibition enhances the protective effect of hucMSC-derived exosome in Aβ(1-40) -induced SH-SY5Y cells by increasing NEP expression.
Chen H, Huang Z, Lei A, Yu X, Shen M, Wu D
Journal of biochemical and molecular toxicology 2024 Jan;38(1):e23624
Journal of biochemical and molecular toxicology 2024 Jan;38(1):e23624
Endoplasmic reticulum stress-mediated autophagy alleviates lipopolysaccharide-induced nucleus pulposus cell pyroptosis by inhibiting CHOP signaling in vitro.
Chen L, Zhu L, Shi H, Xie ZY, Jiang ZL, Xu ZY, Zhang ZJ, Wu XT
Journal of biochemical and molecular toxicology 2024 Jan;38(1):e23523
Journal of biochemical and molecular toxicology 2024 Jan;38(1):e23523
Integrating network pharmacology and transcriptomic omics reveals that akebia saponin D attenuates neutrophil extracellular traps-induced neuroinflammation via NTSR1/PKAc/PAD4 pathway after intracerebral hemorrhage.
Gu L, Ye L, Chen Y, Deng C, Zhang X, Chang J, Feng M, Wei J, Bao X, Wang R
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan;38(1):e23394
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan;38(1):e23394
IL-21 promoting angiogenesis contributes to the development of psoriasis.
Han D, Li F, Zhao Y, Wang B, Wang J, Liu B, Mou K, Meng L, Zheng Y, Lu S, Zhu W, Zhou Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan;38(1):e23375
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan;38(1):e23375
A responsive hydrogel modulates innate immune cascade fibrosis to promote ocular surface reconstruction after chemical injury.
Zhang J, Su L, Liu Z, Tang J, Zhang L, Li Z, Zhou D, Sun Z, Xi K, Lu P, Deng G
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:1124-1138
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:1124-1138
PVT1 promotes proliferation and macrophage immunosuppressive polarization through STAT1 and CX3CL1 regulation in glioblastoma multiforme.
Huang L, Wang Z, Liao C, Zhao Z, Gao H, Huang R, Chen J, Wu F, Zeng F, Zhang Y, Jiang T, Hu H
CNS neuroscience & therapeutics 2024 Jan;30(1):e14566
CNS neuroscience & therapeutics 2024 Jan;30(1):e14566
USP11 promotes glycolysis by regulating HIF-1α stability in hepatocellular carcinoma.
Qiao L, Hu W, Li L, Chen X, Liu L, Wang J
Journal of cellular and molecular medicine 2024 Jan;28(2):e18017
Journal of cellular and molecular medicine 2024 Jan;28(2):e18017
ER-α36 is involved in calycosin inhibition of IL-6 production in macrophages.
Wu G, Qi G, Liu Y, Gan J, Xie C, Wu Q, Cui W, Wang C, Wang Z
Journal of cellular and molecular medicine 2024 Jan;28(1):e18037
Journal of cellular and molecular medicine 2024 Jan;28(1):e18037
Berberine alleviates contrast-induced nephropathy by activating Akt/Foxo3a/Nrf2 signalling pathway.
Wang W, Yu R, Wu C, Li Q, Chen J, Xiao Y, Chen H, Song J, Ji M, Zuo Z
Journal of cellular and molecular medicine 2024 Jan;28(1):e18016
Journal of cellular and molecular medicine 2024 Jan;28(1):e18016
Localization and expression of phospholipase A(2) and polyunsaturated fatty acid profile in the testis tissues of Hu sheep.
Liang W, Zhao Y, Quan G, Yao R, Chen H, Weng X, Li W, Yue X, Li F
Animal reproduction science 2024 Jan;260:107381
Animal reproduction science 2024 Jan;260:107381
pH-driven preparation of pea protein isolate-curcumin nanoparticles effectively enhances antitumor activity.
Ren J, Wu H, Lu Z, Qin Q, Jiao X, Meng G, Liu W, Li G
International journal of biological macromolecules 2024 Jan;256(Pt 1):128383
International journal of biological macromolecules 2024 Jan;256(Pt 1):128383
Angiotensin-converting enzyme inhibitory peptide IVGFPAYGH protects against liver injury in mice fed a high‑sodium diet by inhibiting the RAS and remodeling gut microbial communities.
Zou L, Yu X, Cai K, Xu B, Chen C, Xiao G
International journal of biological macromolecules 2024 Jan;256(Pt 1):128265
International journal of biological macromolecules 2024 Jan;256(Pt 1):128265
A hyaluronic acid / chitosan composite functionalized hydrogel based on enzyme-catalyzed and Schiff base reaction for promoting wound healing.
Li J, Su J, Liang J, Zhang K, Xie M, Cai B, Li J
International journal of biological macromolecules 2024 Jan;255:128284
International journal of biological macromolecules 2024 Jan;255:128284
Suppression of the SLC7A11/glutathione axis causes ferroptosis and apoptosis and alters the mitogen-activated protein kinase pathway in nasopharyngeal carcinoma.
Wang HH, Fan SQ, Zhan YT, Peng SP, Wang WY
International journal of biological macromolecules 2024 Jan;254(Pt 3):127976
International journal of biological macromolecules 2024 Jan;254(Pt 3):127976
Valine promotes milk synthesis by regulating PKM2 nuclear accumulation and histone H3 acetylation through the TAS1R1-mTOR-DDX39B signaling pathway.
Cao Y, Hu G, Long X, Li F, Wang J, Sun M, Xie Y, Ge Y, Guo W, Liu J, Fu S
International journal of biological macromolecules 2024 Jan;254(Pt 3):127786
International journal of biological macromolecules 2024 Jan;254(Pt 3):127786
A novel lncRNA GM15416 regulates osteoblast apoptosis and differentiation through the c-Fos/Fas axis and mitigates osteoporosis.
Zhao D, He J, Zhao X, Sheng X, Feng Z, Wang X, Zhang C, Wang S, Geng B, Xia Y
International journal of biological macromolecules 2024 Jan;254(Pt 2):127824
International journal of biological macromolecules 2024 Jan;254(Pt 2):127824
Fibroblast growth factor-21 alleviates proteasome injury via activation of autophagy flux in Parkinson's disease.
Shen Y, Zhu Z, Wang Y, Qian S, Xu C, Zhang B
Experimental brain research 2024 Jan;242(1):25-32
Experimental brain research 2024 Jan;242(1):25-32
Crocetin inhibits choroidal neovascularization in both in vitro and in vivo models.
Wang C, Li X, Su J, Duan J, Yao Y, Shang Q
Experimental eye research 2024 Jan;238:109751
Experimental eye research 2024 Jan;238:109751
Driver gene KRAS aggravates cancer-associated stroke outcomes.
Yan H, Sasaki T, Gon Y, Nishiyama K, Kanki H, Mochizuki H
Thrombosis research 2024 Jan;233:55-68
Thrombosis research 2024 Jan;233:55-68
Carrier-free nanodrug targeting glucose metabolism for enhanced rheumatoid arthritis treatment.
Chen T, Lin X, Li D, Pan L, Qin X, Ye W, Luo Z, Wang Q
Colloids and surfaces. B, Biointerfaces 2024 Jan;233:113668
Colloids and surfaces. B, Biointerfaces 2024 Jan;233:113668
MiR-548t-5p regulates pancreatic ductal adenocarcinoma metastasis through an IL-33-dependent crosstalk between cancer cells and M2 macrophages.
Wang Y, Ge WL, Wang SJ, Liu YY, Zhang ZH, Hua Y, Zhang XF, Zhang JJ
Cell cycle (Georgetown, Tex.) 2024 Jan;23(2):169-187
Cell cycle (Georgetown, Tex.) 2024 Jan;23(2):169-187
KAN0438757, a novel PFKFB3 inhibitor, prevent the progression of severe acute pancreatitis via the Nrf2/HO-1 pathway in infiltrated macrophage.
Ergashev A, Shi F, Liu Z, Pan Z, Xie H, Kong L, Wu L, Sun H, Jin Y, Kong H, Geng D, Ibrohimov A, Obeng E, Wang Y, Ma F, Chen G, Zhang T
Free radical biology & medicine 2024 Jan;210:130-145
Free radical biology & medicine 2024 Jan;210:130-145
Electroacupuncture ameliorates chronic unpredictable mild stress-induced depression-like behavior and cognitive impairment through suppressing oxidative stress and neuroinflammation in rats.
Tong T, Hao C, Shen J, Liu S, Yan S, Aslam MS, Chen Y, Chen W, Li J, Li Y, Zeng J, Li M, You Z, Gulizhaerkezi T, Wei S, Zhu A, Meng X
Brain research bulletin 2024 Jan;206:110838
Brain research bulletin 2024 Jan;206:110838
Pseudorabies virus inhibits progesterone-induced inactivation of TRPML1 to facilitate viral entry.
Su BQ, Yang GY, Wang J, Ming SL, Chu BB
PLoS pathogens 2024 Jan;20(1):e1011956
PLoS pathogens 2024 Jan;20(1):e1011956
CENPL accelerates cell proliferation, cell cycle, apoptosis, and glycolysis via the MEK1/2-ERK1/2 pathway in hepatocellular carcinoma.
He K, Xie M, Hong W, Li Y, Yin Y, Gao X, He Y, Chen Y, You C, Li J
The international journal of biochemistry & cell biology 2024 Jan;166:106481
The international journal of biochemistry & cell biology 2024 Jan;166:106481
IFN-γ enhances the therapeutic efficacy of MSCs-derived exosome via miR-126-3p in diabetic wound healing by targeting SPRED1.
Lu W, Du X, Zou S, Fang Q, Wu M, Li H, Shi B
Journal of diabetes 2024 Jan;16(1):e13465
Journal of diabetes 2024 Jan;16(1):e13465
Costunolide ameliorates angiotensin II-induced atrial inflammation and fibrosis by regulating mitochondrial function and oxidative stress in mice: A possible therapeutic approach for atrial fibrillation.
Liu Y, Wang D, Jin Y, Sun G, Lou Q, Wang H, Li W
Microvascular research 2024 Jan;151:104600
Microvascular research 2024 Jan;151:104600
Bushen Antai recipe alleviates embryo absorption by enhancing immune tolerance and angiogenesis at the maternal-fetal interface via mobilizing MDSCs in abortion-prone mice.
Liu Z, Geng Y, Huang Y, Hu R, Li F, Ding J, Ma W, Dong H, Song K, Xu X, Wu X, Song Y, Zhang M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155164
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155164
Liproxstatin-1 alleviates cartilage degradation by inhibiting chondrocyte ferroptosis in the temporomandibular joint.
Cheng B, Zhang J, Shen Q, Sun Z, Luo Y, Hu Y
Biology of the cell 2024 Jan;116(1):e202300042
Biology of the cell 2024 Jan;116(1):e202300042
Decreased FoxO1 expression contributes to facet joint osteoarthritis pathogenesis by impairing chondrocyte migration and extracellular matrix synthesis.
Chen C, Xu G, Chen J, Wu C, Zhang J, Jiang J, Hong H, Cui Z
Cellular signalling 2024 Jan;113:110942
Cellular signalling 2024 Jan;113:110942
Chrysophanol induces apoptosis and ferroptosis of gastric cancer cells by targeted regulation of mTOR.
Xi S, Ding W, Weng D, Zeng Y, Gao K, Wu Q, Huang G, Li Y, Yue H
Chemical biology & drug design 2024 Jan;103(1):e14417
Chemical biology & drug design 2024 Jan;103(1):e14417
Discovery of small molecule c-Maf inhibitors using molecular docking-based virtual screening, molecular dynamics simulation, and biological evaluation.
Hu Z, Zeng Y, Zhang Y, Zhang Q, Xu J, Liu L
Chemical biology & drug design 2024 Jan;103(1):e14403
Chemical biology & drug design 2024 Jan;103(1):e14403
Hsa_circ_0013561 promotes progression of nasopharyngeal carcinoma by activating JAK2/STAT3 signaling pathway.
Kaisai T, Mantang Z, Tailei Y, Liying Z, Xiaoping C, Mingming J, Yi Z
Brazilian journal of otorhinolaryngology 2024 Jan-Feb;90(1):101362
Brazilian journal of otorhinolaryngology 2024 Jan-Feb;90(1):101362
Polyphyllin II (PPII) Enhances the Sensitivity of Multidrug-resistant A549/DDP Cells to Cisplatin by Modulating Mitochondrial Energy Metabolism.
Peng L, Yang R, Wang Z, Jian H, Tan X, Li J, He Z, Huang R, Zeng P, Gao W
In vivo (Athens, Greece) 2024 Jan-Feb;38(1):213-225
In vivo (Athens, Greece) 2024 Jan-Feb;38(1):213-225
Protective effects of sodium humate on the intestinal barrier damage of Salmonella Typhimurium-challenged broilers.
Ma W, Zou X, Sun X, Wang W, Liu K, He Y, Liu Y, Wang D
Animal science journal = Nihon chikusan Gakkaiho 2024 Jan-Dec;95(1):e14004
Animal science journal = Nihon chikusan Gakkaiho 2024 Jan-Dec;95(1):e14004
The Herbal Combination Shu Gan Jie Yu Regulates the SNCG/ER-a/AKT-ERK Pathway in DMBA-Induced Breast Cancer and Breast Cancer Cell Lines Based on RNA-Seq and IPA Analysis.
Zhao Y, Zhao L, Wang T, Liu Z, Tang S, Huang H, Wu L, Sun Y
Integrative cancer therapies 2024 Jan-Dec;23:15347354241233258
Integrative cancer therapies 2024 Jan-Dec;23:15347354241233258
Systematic Characterization of DNA Methyltransferases Family in Tumor Progression and Antitumor Immunity.
Huang F, Wu X, Du Q, Lin J, Ma W, Liu J
Technology in cancer research & treatment 2024 Jan-Dec;23:15330338241260658
Technology in cancer research & treatment 2024 Jan-Dec;23:15330338241260658
CRYL1 is a Potential Prognostic Biomarker of Clear Cell Renal Cell Carcinoma Correlated with Immune Infiltration and Cuproptosis.
Li P, Xu Q, Liu K, Ye J
Technology in cancer research & treatment 2024 Jan-Dec;23:15330338241237439
Technology in cancer research & treatment 2024 Jan-Dec;23:15330338241237439
Vancomycin relieves tacrolimus-induced hyperglycemia by eliminating gut bacterial beta-glucuronidase enzyme activity.
Li P, Zhang R, Zhou J, Guo P, Liu Y, Shi S
Gut microbes 2024 Jan-Dec;16(1):2310277
Gut microbes 2024 Jan-Dec;16(1):2310277
Lysosomal dynamics regulate mammalian cortical neurogenesis.
Zou W, Lv Y, Zhang S, Li L, Sun L, Jiao J
Developmental cell 2024 Jan 8;59(1):64-78.e5
Developmental cell 2024 Jan 8;59(1):64-78.e5
BACH1 changes microglial metabolism and affects astrogenesis during mouse brain development.
Wang Y, Wang W, Su L, Ji F, Zhang M, Xie Y, Zhang T, Jiao J
Developmental cell 2024 Jan 8;59(1):108-124.e7
Developmental cell 2024 Jan 8;59(1):108-124.e7
Aureusidin ameliorates 6-OHDA-induced neurotoxicity via activating Nrf2/HO-1 signaling pathway and preventing mitochondria-dependent apoptosis pathway in SH-SY5Y cells and Caenorhabditis elegans.
Hu K, Zhu S, Wu F, Zhang Y, Li M, Yuan L, Huang W, Zhang Y, Wang J, Ren J, Yang H
Chemico-biological interactions 2024 Jan 5;387:110824
Chemico-biological interactions 2024 Jan 5;387:110824
Autophagy induces hair follicle stem cell activation and hair follicle regeneration by regulating glycolysis.
Sun P, Wang Z, Li S, Yin J, Gan Y, Liu S, Lin Z, Wang H, Fan Z, Qu Q, Hu Z, Li K, Miao Y
Cell & bioscience 2024 Jan 5;14(1):6
Cell & bioscience 2024 Jan 5;14(1):6
miR-99b-3p/Mmp13 axis regulates NLRP3 inflammasome-dependent microglial pyroptosis and alleviates neuropathic pain via the promotion of autophagy.
Gao X, Gao LF, Zhang ZY, Jia S, Meng CY
International immunopharmacology 2024 Jan 5;126:111331
International immunopharmacology 2024 Jan 5;126:111331
Unlocking the role of EIF5A: A potential diagnostic marker regulating the cell cycle and showing negative correlation with immune infiltration in lung adenocarcinoma.
Yang Z, Yuan H, He H, Qi S, Zhu X, Hu X, Jin M, Zhang XX, Yuan ZG
International immunopharmacology 2024 Jan 5;126:111227
International immunopharmacology 2024 Jan 5;126:111227
Protective Effect of Artocarpus heterophyllus Lam. (Jackfruit) Polysaccharides on Liver Injury Induced by Cyclophosphamide in Mice.
Cheng M, Zheng Y, Wu G, Tan L, Xu F, Zhang Y, Chen X, Zhu K
Nutrients 2024 Jan 4;16(1)
Nutrients 2024 Jan 4;16(1)
MiR-199a-5p inhibits dermal papilla cells proliferation by regulating VEGFA expression in cashmere goat.
Zhang T, Zheng Y, Zhang F, Wang X, Du J, Wang X
Gene 2024 Jan 30;893:147901
Gene 2024 Jan 30;893:147901
Texture maintenance and degradation mechanism of ice-stored grass carp (Ctenopharyngodon idella): A scope of intramuscular connective tissue.
Yang F, Teng J, Liu J, Yu D, Gao P, Yu P, Jiang Q, Xu Y, Xia W
Food chemistry 2024 Jan 30;432:137256
Food chemistry 2024 Jan 30;432:137256
Investigation of the principle of concoction by using the processing excipient Glycyrrhiza uralensis Fisch. juice to reduce the main toxicity of Dioscorea bulbifera L. and enhance its main efficacy as expectorant and cough suppressant.
Song L, Wang J, Gong M, Duan Y, Zhang Y, Li Y, Qin L, He Q, Ji L, Zhang T, Wu X, Wang Y
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117372
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117372
Flavonoid extract from propolis alleviates periodontitis by boosting periodontium regeneration and inflammation resolution via regulating TLR4/MyD88/NF-κB and RANK/NF-κB pathway.
Tang M, Wang G, Li J, Wang Y, Peng C, Chang X, Guo J, Gui S
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117324
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117324
Xingbei antitussive granules ameliorate cough hypersensitivity in post-infectious cough guinea pigs by regulating tryptase/PAR2/TRPV1 pathway.
Li Y, Zhao R, Zhang M, Shen K, Hou X, Liu B, Li C, Sun B, Xiang M, Lin J
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117243
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117243
Rescuing SERCA2 pump deficiency improves bone mechano-responsiveness in type 2 diabetes by shaping osteocyte calcium dynamics.
Shao X, Tian Y, Liu J, Yan Z, Ding Y, Hao X, Wang D, Shen L, Luo E, Guo XE, Luo P, Luo W, Cai J, Jing D
Nature communications 2024 Jan 30;15(1):890
Nature communications 2024 Jan 30;15(1):890
HIF-1A as a prognostic biomarker related to invasion, migration and immunosuppression of cervical cancer.
Li Z, Wei R, Yao S, Meng F, Kong L
Heliyon 2024 Jan 30;10(2):e24664
Heliyon 2024 Jan 30;10(2):e24664
The Tautomerase Activity of Tumor Exosomal MIF Promotes Pancreatic Cancer Progression by Modulating MDSC Differentiation.
Jia X, Xi J, Tian B, Zhang Y, Wang Z, Wang F, Li Z, Long J, Wang J, Fan GH, Li Q
Cancer immunology research 2024 Jan 3;12(1):72-90
Cancer immunology research 2024 Jan 3;12(1):72-90
The inflammatory injury of porcine small intestinal epithelial cells induced by deoxynivalenol is related to the decrease in glucose transport.
Tang X, Zeng Y, Xiong K, Li M
Journal of animal science 2024 Jan 3;102
Journal of animal science 2024 Jan 3;102
Real-time monitoring of glucose metabolism and effects of metformin on HepG2 cells using (13)C in-cell NMR spectroscopy.
Teng M, Li Z, Gu Y, Fan Y, Wang D, Liu M, Li Y, Wei G, Huang Y
Biochemical and biophysical research communications 2024 Jan 29;694:149383
Biochemical and biophysical research communications 2024 Jan 29;694:149383
Visualization of the membrane surface and cytoskeleton of oligodendrocyte progenitor cell growth cones using a combination of scanning ion conductance and four times expansion microscopy.
Haak A, Lesslich HM, Dietzel ID
Biological chemistry 2024 Jan 29;405(1):31-41
Biological chemistry 2024 Jan 29;405(1):31-41
Construction and Identification of a Breast Bioreactor for Human-Derived Hypoglycemic Protein Amylin.
Huang K, Yan X, Li Z, Liu F, Cui K, Liu Q
Life (Basel, Switzerland) 2024 Jan 28;14(2)
Life (Basel, Switzerland) 2024 Jan 28;14(2)
κ-Opioid receptor activation attenuates osteoarthritis synovitis by regulating macrophage polarization through the NF-κB pathway.
Shi Y, Tao H, Li X, Zhang L, Li C, Sun W, Chu M, Chen K, Zhu P, Wang Q, Gu C, Wang L, Yang X, Hao Y
Acta biochimica et biophysica Sinica 2024 Jan 25;56(1):82-95
Acta biochimica et biophysica Sinica 2024 Jan 25;56(1):82-95
Sodium humate ameliorates LPS-induced liver injury in mice by inhibiting TLR4/NF-κB and activating NRF2/HO-1 signaling pathways.
Ma W, Liu K, He Y, Deng S, Liu Y, Wang D
Molecular biology reports 2024 Jan 25;51(1):204
Molecular biology reports 2024 Jan 25;51(1):204
LGK974 suppresses the formation of deep vein thrombosis in mice with sepsis.
Li Z, Shan X, Yang G, Dong L
International immunopharmacology 2024 Jan 25;127:111458
International immunopharmacology 2024 Jan 25;127:111458
Monotropein induces autophagy through activation of the NRF2/PINK axis, thereby alleviating sepsis-induced colonic injury.
Qiang J, Yang R, Li X, Xu X, Zhou M, Ji X, Lu Y, Dong Z
International immunopharmacology 2024 Jan 25;127:111432
International immunopharmacology 2024 Jan 25;127:111432
CXCL16 exacerbates Pseudomonas aeruginosa keratitis by promoting neutrophil activation.
Wu J, Wang W, Yuan F, Zheng J, Zhang W, Guo H, Wang L, Dai C, Han F, Wu X, Gao J
International immunopharmacology 2024 Jan 25;127:111375
International immunopharmacology 2024 Jan 25;127:111375
Regulation of tumor metastasis and CD8(+) T cells infiltration by circRNF216/miR-576-5p/ZC3H12C axis in colorectal cancer.
Du W, Quan X, Wang C, Song Q, Mou J, Pei D
Cellular & molecular biology letters 2024 Jan 24;29(1):19
Cellular & molecular biology letters 2024 Jan 24;29(1):19
Veratramine inhibits porcine epidemic diarrhea virus entry through macropinocytosis by suppressing PI3K/Akt pathway.
Chen H, Zhao P, Zhang C, Ming X, Zhang C, Jung YS, Qian Y
Virus research 2024 Jan 2;339:199260
Virus research 2024 Jan 2;339:199260
Tetrandrine (TET) inhibits African swine fever virus entry into cells by blocking the PI3K/Akt pathway.
Qian B, Hu Y, Liu C, Zheng D, Han X, Gong M, Zou Y, Zeng D, Liao K, Miao Y, Wu X, Dai J, Wang Z, Xue F
Virus research 2024 Jan 2;339:199258
Virus research 2024 Jan 2;339:199258
LncRNA FOXD1-AS1 regulates pancreatic cancer stem cell properties and 5-FU resistance by regulating the miR-570-3p/SPP1 axis as a ceRNA.
Ouyang L, Sun MM, Zhou PS, Ren YW, Liu XY, Wei WY, Song ZS, Lu K, Yang LX
Cancer cell international 2024 Jan 2;24(1):4
Cancer cell international 2024 Jan 2;24(1):4
Perfluorocarbon Nanoparticles Incorporating Ginkgolide B: Artificial O(2) Carriers with Antioxidant Activity and Antithrombotic Effect.
Meng W, Ye H, Ma Z, Liu L, Zhang T, Han Q, Xiang Z, Xia Y, Ke Y, Guan X, Shi Q, Ataullakhanov FI, Panteleev M
ChemMedChem 2024 Jan 2;19(1):e202300312
ChemMedChem 2024 Jan 2;19(1):e202300312
Proteomic analysis identifies PFKP lactylation in SW480 colon cancer cells.
Cheng Z, Huang H, Li M, Chen Y
iScience 2024 Jan 19;27(1):108645
iScience 2024 Jan 19;27(1):108645
Identification of key ferroptosis genes and mechanisms associated with breast cancer using bioinformatics, machine learning, and experimental validation.
Liang S, Bai YM, Zhou B
Aging 2024 Jan 19;16(2):1781-1795
Aging 2024 Jan 19;16(2):1781-1795
Macrophage-expressed SRA ameliorates alcohol-induced liver injury by suppressing S-glutathionylation of Notch1 via recruiting thioredoxin.
Li L, Luo J, Zhu Z, Wang P, Xu Q, Chang B, Wang D, Yu L, Lu X, Zhou J, Chen Q, Zuo D
Journal of leukocyte biology 2024 Jan 19;115(2):322-333
Journal of leukocyte biology 2024 Jan 19;115(2):322-333
Hypoxia-induced P4HA1 overexpression promotes post-ischemic angiogenesis by enhancing endothelial glycolysis through downregulating FBP1.
Xu Y, Xia D, Huang K, Liang M
Journal of translational medicine 2024 Jan 18;22(1):74
Journal of translational medicine 2024 Jan 18;22(1):74
SLC7A8 overexpression inhibits the growth and metastasis of lung adenocarcinoma and is correlated with a dismal prognosis.
Wang FM, Xu LQ, Zhang ZC, Guo Q, Du ZP, Lei Y, Han X, Wu CY, Zhao F, Chen JL
Aging 2024 Jan 18;16(2):1605-1619
Aging 2024 Jan 18;16(2):1605-1619
The mitochondrial ATP-dependent potassium channel (mitoK(ATP)) controls skeletal muscle structure and function.
Di Marco G, Gherardi G, De Mario A, Piazza I, Baraldo M, Mattarei A, Blaauw B, Rizzuto R, De Stefani D, Mammucari C
Cell death & disease 2024 Jan 17;15(1):58
Cell death & disease 2024 Jan 17;15(1):58
Neutrophil extracellular trap-related mechanisms in acne vulgaris inspire a novel treatment strategy with adipose-derived stem cells.
Yu H, Zhang B, Zhan Y, Yi Y, Jiang Q, Zhang Q, Wu Y, Wu M
Scientific reports 2024 Jan 17;14(1):1521
Scientific reports 2024 Jan 17;14(1):1521
Activation of TAZ by XMU-MP-1 inhibits osteoclastogenesis and attenuates ovariectomy-induced cancellous bone loss.
Li X, Lou Y, Hu W, Wang K, Zhang Y, Xu R, Zhang T, Yang W, Qian Y
Biochemical and biophysical research communications 2024 Jan 15;692:149323
Biochemical and biophysical research communications 2024 Jan 15;692:149323
Mechanism through which the hsa-circ_0000992- hsa- miR- 936-AKT3 regulatory network promotes the PM(2.5)-induced inflammatory response in human bronchial epithelial cells.
Li JL, Tan Y, Wang QL, Li CX, Hong JC, Wang HJ, Wu Y, Ni C, Peng XW
Ecotoxicology and environmental safety 2024 Jan 15;270:115778
Ecotoxicology and environmental safety 2024 Jan 15;270:115778
Fluorochloridone induces mitochondrial dysfunction and apoptosis in primary goat Sertoli cells.
Li Y, Li L, Xiong W, Duan X, Xi H
Theriogenology 2024 Jan 15;214:192-200
Theriogenology 2024 Jan 15;214:192-200
Resveratrol-βcd inhibited premature ovarian insufficiency progression by regulating granulosa cell autophagy.
Hu B, Zheng X, Zhang W
Journal of ovarian research 2024 Jan 15;17(1):18
Journal of ovarian research 2024 Jan 15;17(1):18
Analysis of the effects of importin α1 on the nuclear translocation of IL-1α in HeLa cells.
Yamada A, Wake K, Imaoka S, Motoyoshi M, Yamamoto T, Asano M
Scientific reports 2024 Jan 15;14(1):1322
Scientific reports 2024 Jan 15;14(1):1322
The tertiary lymphoid structure-related signature identified PTGDS in regulating PD-L1 and promoting the proliferation and migration of glioblastoma.
Wu W, Li H, Wang Z, Dai Z, Liang X, Luo P, Liu K, Zhang H, Zhang N, Li S, Zhang C
Heliyon 2024 Jan 15;10(1):e23915
Heliyon 2024 Jan 15;10(1):e23915
Dictamnine Ameliorates DNFB-Induced Atopic Dermatitis Like Skin Lesions in Mice by Inhibiting M1 Macrophage Polarization and Promoting Autophagy.
Huang Y, Zhao C, Zheng G, Yuan Y, Gong L, Liu R, An J
Biological & pharmaceutical bulletin 2024 Jan 13;47(1):175-186
Biological & pharmaceutical bulletin 2024 Jan 13;47(1):175-186
Metabolic reprogramming based on RNA sequencing of gemcitabine-resistant cells reveals the FASN gene as a therapeutic for bladder cancer.
Zhou L, Du K, Dai Y, Zeng Y, Luo Y, Ren M, Pan W, Liu Y, Zhang L, Zhu R, Feng D, Tian F, Gu C
Journal of translational medicine 2024 Jan 13;22(1):55
Journal of translational medicine 2024 Jan 13;22(1):55
Molecular and functional characterization of porcine poly C binding protein 1 (PCBP1).
Song Y, Wang L, Xu M, Lu X, Wang Y, Zhang L
BMC veterinary research 2024 Jan 13;20(1):25
BMC veterinary research 2024 Jan 13;20(1):25
FBXO31 is upregulated by METTL3 to promote pancreatic cancer progression via regulating SIRT2 ubiquitination and degradation.
Chen K, Wang Y, Dai X, Luo J, Hu S, Zhou Z, Shi J, Pan X, Cao T, Xia J, Li Y, Wang Z, Ma J
Cell death & disease 2024 Jan 12;15(1):37
Cell death & disease 2024 Jan 12;15(1):37
SLMO2 is a potential prognostic and immunological biomarker in human pan-cancer.
Liu X, Yuan R, Peng J, Xu A, Nie X, Tang R, Li G
Scientific reports 2024 Jan 11;14(1):1070
Scientific reports 2024 Jan 11;14(1):1070
Phosphoproteomic landscape of pseudorabies virus infection reveals multiple potential antiviral targets.
Bo Z, Li X, Zhang C, Guo M, Cao Y, Zhang X, Wu Y
Microbiology spectrum 2024 Jan 11;12(1):e0301023
Microbiology spectrum 2024 Jan 11;12(1):e0301023
Jianghu decoction and its active component polydatin inhibit inflammation and fibrotic lesions in the lungs of ILD mice via the AMPK signaling pathway.
Zhang Z, Deng X, Gu W, Jiao Y, Su C, Liu H, Ma W, Zhang H, Xiang R, Wang D, Wang Y, Chunguo W, Meng F
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117003
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117003
Neuroprotective effects of Jie-du-huo-xue decoction on microglia pyroptosis after cerebral ischemia and reperfusion--From the perspective of glial-vascular unit.
Zhou C, Li JX, Zheng CX, Zhou XQ, Chen C, Qiu SW, Liu WH, Li H
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):116990
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):116990
Therapeutic effect of Hosta plantaginea (Lam.) Aschers flowers on acute pharyngitis through inhibition of multi-inflammatory pathways in rats.
Wang J, Cao L, Wang H, Huang H, Zhong G, Yang L, He J
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116966
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116966
Bushen Antai recipe ameliorates immune microenvironment and maternal-fetal vascularization in STAT3-deficient abortion-prone mice.
Liu Z, Song Y, Hu R, Geng Y, Huang Y, Li F, Ma W, Dong H, Song K, Ding J, Xu X, Wu X, Zhang M, Zhong Z
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116889
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116889
Network pharmacology, molecular docking and experimental verification of the mechanism of huangqi-jixuecao herb pair in treatment of peritoneal fibrosis.
Dai H, Shan Y, Yu M, Wang F, Zhou Z, Sun J, Sheng L, Huang L, Sheng M
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116874
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116874
Qinzhizhudan formula dampens inflammation in microglia polarization of vascular dementia rats by blocking MyD88/NF-κB signaling pathway: Through integrating network pharmacology and experimental validation.
Chen CA, Li CX, Zhang ZH, Xu WX, Liu SL, Ni WC, Wang XQ, Cheng FF, Wang QG
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116769
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116769
A novel upregulated hsa_circ_0032746 regulates the oncogenesis of esophageal squamous cell carcinoma by regulating miR-4270/MCM3 axis.
Shrestha SM, Fang X, Ye H, Ren L, Ji Q, Shi R
Human genomics 2024 Jan 10;18(1):3
Human genomics 2024 Jan 10;18(1):3
MitomiR-1736-3p regulates copper-induced mitochondrial pathway apoptosis by inhibiting AATF in chicken hepatocytes.
Li Y, Zhong G, Li L, Li T, Li H, Li Y, Zhang H, Pan J, Hu L, Liao J, Yu W, Tang Z
The Science of the total environment 2024 Jan 1;906:167825
The Science of the total environment 2024 Jan 1;906:167825
miR-130b regulates B cell proliferation via CYLD-mediated NF-κB signaling.
Wu M, Zhao J, Wu W, Hao C, Yang Y, Zhang J
Experimental cell research 2024 Jan 1;434(1):113870
Experimental cell research 2024 Jan 1;434(1):113870
Mechanistic study of the Aldo-keto reductase family 1 member A1 in regulating mesenchymal stem cell fate decision toward adipogenesis and osteogenesis.
Chiang CH, Lin YH, Kao YC, Weng SC, Chen CM, Liou YM
Life sciences 2024 Jan 1;336:122336
Life sciences 2024 Jan 1;336:122336
Fenofibrate inhibits MOXD1 and PDZK1IP1 expression and improves lipid deposition and inflammation in mice with alcoholic fatty liver.
Pan T, Zhao Z, Lu J, Wen H, Zhang J, Xu Y, Chen Y, Jin X
Life sciences 2024 Jan 1;336:122321
Life sciences 2024 Jan 1;336:122321
Anticancer effect of covalent purine-containing EGFR TKI, ZZC4 and its mechanism of action through network pharmacology.
Attiogbe MKI, Zhao HY, Wang J, Huang TT, Yan PP, Liu YN, Li W, Cao L, Zhang SQ, Cao YX
Life sciences 2024 Jan 1;336:122308
Life sciences 2024 Jan 1;336:122308
Patulin induces ROS-dependent cardiac cell toxicity by inducing DNA damage and activating endoplasmic reticulum stress apoptotic pathway.
Zhang B, Huang C, Xu D, Huang K, Li Y, Jiao L, Fu B, Li S, Li Y
Ecotoxicology and environmental safety 2024 Jan 1;269:115784
Ecotoxicology and environmental safety 2024 Jan 1;269:115784
2-Deoxy-D-glucose ameliorates inflammation and fibrosis in a silicosis mouse model by inhibiting hypoxia-inducible factor-1α in alveolar macrophages.
Lu Y, Mu M, RenChen X, Wang W, Zhu Y, Zhong M, Jiang Y, Tao X
Ecotoxicology and environmental safety 2024 Jan 1;269:115767
Ecotoxicology and environmental safety 2024 Jan 1;269:115767
SARS-CoV-2 nucleocapsid protein promotes TMAO-induced NLRP3 inflammasome activation by SCAP-SREBP signaling pathway.
Liu MH, Lin XL, Xiao LL
Tissue & cell 2024 Feb;86:102276
Tissue & cell 2024 Feb;86:102276
Heterogeneous ferroptosis susceptibility of macrophages caused by focal iron overload exacerbates rheumatoid arthritis.
Liu Y, Luo X, Chen Y, Dang J, Zeng D, Guo X, Weng W, Zhao J, Shi X, Chen J, Dong B, Zhong S, Ren J, Li Y, Wang J, Zhang J, Sun J, Xu H, Lu Y, Brand D, Zheng SG, Pan Y
Redox biology 2024 Feb;69:103008
Redox biology 2024 Feb;69:103008
Enhancing HIF-1α-P2X2 signaling in dorsal raphe serotonergic neurons promotes psychological resilience.
Zhang Y, Pan YD, Zheng WY, Li HY, Zhu MZ, Ou Yang WJ, Qian Y, Turecki G, Mechawar N, Zhu XH
Redox biology 2024 Feb;69:103005
Redox biology 2024 Feb;69:103005
Lead aggravates Alzheimer's disease pathology via mitochondrial copper accumulation regulated by COX17.
Huang D, Chen L, Ji Q, Xiang Y, Zhou Q, Chen K, Zhang X, Zou F, Zhang X, Zhao Z, Wang T, Zheng G, Meng X
Redox biology 2024 Feb;69:102990
Redox biology 2024 Feb;69:102990
Partial Replacement of NaCl with KCl in Cooked Meat Could Reduce the Liver Damage Through Renin-Angiotensin System in Mice.
Zou L, Yu X, Xiong J, Chen C, Xiao G
Molecular nutrition & food research 2024 Feb;68(4):e2200783
Molecular nutrition & food research 2024 Feb;68(4):e2200783
SENP1 inhibits ferroptosis and promotes head and neck squamous cell carcinoma by regulating ACSL4 protein stability via SUMO1.
Xu X, Mao Y, Feng Z, Dai F, Gu T, Zheng J
Oncology reports 2024 Feb;51(2)
Oncology reports 2024 Feb;51(2)
Prenylated flavonoid fractions from Glycyrrhiza glabra alleviate insulin resistance in HepG2 cells by regulating the ERK/IRS-1 and PI3K/Akt signaling pathways.
Li D, Fan J, Du L, Ren G
Archives of pharmacal research 2024 Feb;47(2):127-145
Archives of pharmacal research 2024 Feb;47(2):127-145
FPR1 Antagonist (BOC-MLF) Inhibits Amniotic Epithelial-mesenchymal Transition.
Huang XM, Liao E, Liao JQ, Liu YL, Shao Y
Current medical science 2024 Feb;44(1):187-194
Current medical science 2024 Feb;44(1):187-194
SENP3 Promotes Mantle Cell Lymphoma Development through Regulating Wnt10a Expression.
Ma YN, Zou YD, Liu ZL, Wu GX, Zhou YZ, Luo CX, Huang XT, Xie ML, Xu SN, Li X
Current medical science 2024 Feb;44(1):134-143
Current medical science 2024 Feb;44(1):134-143
Liver ACSM3 deficiency mediates metabolic syndrome via a lauric acid-HNF4α-p38 MAPK axis.
Xiao X, Li R, Cui B, Lv C, Zhang Y, Zheng J, Hui R, Wang Y
The EMBO journal 2024 Feb;43(4):507-532
The EMBO journal 2024 Feb;43(4):507-532
miR-1182-mediated ALDH3A2 inhibition affects lipid metabolism and progression in ccRCC by activating the PI3K-AKT pathway.
Lv Q, Shi J, Miao D, Tan D, Zhao C, Xiong Z, Zhang X
Translational oncology 2024 Feb;40:101835
Translational oncology 2024 Feb;40:101835
USP14 promotes the proliferation of cervical cancer via upregulating β-catenin.
Song H, Qiu J, Hua K
Environmental toxicology 2024 Feb;39(2):1031-1043
Environmental toxicology 2024 Feb;39(2):1031-1043
Exosomal circ_0037104 derived from Hu-MSCs inhibits cholangiocarcinoma progression by sponging miR-620 and targeting AFAP1.
Yuan Z, Xiong B, Liu L, Lu Y, Liu Y, Wang G, Qian Y, Diao B, Tu M
Journal of biochemical and molecular toxicology 2024 Feb;38(2):e23656
Journal of biochemical and molecular toxicology 2024 Feb;38(2):e23656
Manganese@Albumin Nanocomplex and Its Assembled Nanowire Activate TLR4-Dependent Signaling Cascades of Macrophages.
Huang S, Gao Y, Li H, Wang R, Zhang X, Wang X, Huang D, Zhang L, Santos HA, Yin Z, Xia B
Advanced materials (Deerfield Beach, Fla.) 2024 Feb;36(5):e2310979
Advanced materials (Deerfield Beach, Fla.) 2024 Feb;36(5):e2310979
Genetically engineered M2-like macrophage-derived exosomes for P. gingivalis-suppressed cementum regeneration: From mechanism to therapy.
Huang X, Deng Y, Xiao J, Wang H, Yang Q, Cao Z
Bioactive materials 2024 Feb;32:473-487
Bioactive materials 2024 Feb;32:473-487
Leveraging synthetic lethality to uncover potential therapeutic target in gastric cancer.
Geng H, Qian R, Zhong Y, Tang X, Zhang X, Zhang L, Yang C, Li T, Dong Z, Wang C, Zhang Z, Zhu C
Cancer gene therapy 2024 Feb;31(2):334-348
Cancer gene therapy 2024 Feb;31(2):334-348
KLF6 activates Sp1-mediated prolidase transcription during TGF-β(1) signaling.
Eni-Aganga I, Lanaghan ZM, Ismail F, Korolkova O, Goodwin JS, Balasubramaniam M, Dash C, Pandhare J
The Journal of biological chemistry 2024 Feb;300(2):105605
The Journal of biological chemistry 2024 Feb;300(2):105605
Identification and validation of a glycolysis-related taxonomy for improving outcomes in glioma.
Ying T, Lai Y, Lu S, E S
CNS neuroscience & therapeutics 2024 Feb;30(2):e14601
CNS neuroscience & therapeutics 2024 Feb;30(2):e14601
Infection of PRRSV inhibits CSFV C-strain replication by inducing macrophages polarization to M1.
Tuo T, Chen D, Wang L, Zhang Y, Zhou L, Ge X, Han J, Guo X, Yang H
Veterinary microbiology 2024 Feb;289:109957
Veterinary microbiology 2024 Feb;289:109957
Anthocyanin Extracted from Purple Sweet Potato Alleviates Dextran Sulfate Sodium-Induced Colitis in Mice by Suppressing Pyroptosis and Altering Intestinal Flora Structure.
Chen J, Jiang F, Xu N, Dong G, Jiang J, Wang M, Li C, Li R
Journal of medicinal food 2024 Feb;27(2):110-122
Journal of medicinal food 2024 Feb;27(2):110-122
Aurora kinase B disruption suppresses pathological retinal angiogenesis by affecting cell cycle progression.
Zhu W, Gui X, Zhou Y, Gao X, Zhang R, Li Q, Zhang H, Zhao J, Cui X, Gao G, Tang H, Huan C, Pan D, Song H, Zhou Z, Shen W
Experimental eye research 2024 Feb;239:109753
Experimental eye research 2024 Feb;239:109753
Discovery of common molecular signatures and drug repurposing for COVID-19/Asthma comorbidity: ACE2 and multi-partite networks.
Xu J, Abdulsalam Khaleel R, Zaidan HK, Faisal Mutee A, Fahmi Fawy K, Gehlot A, Abbas AH, Arias Gonzáles JL, Amin AH, Ruiz-Balvin MC, Imannezhad S, Bahrami A, Akhavan-Sigari R
Cell cycle (Georgetown, Tex.) 2024 Feb;23(4):405-434
Cell cycle (Georgetown, Tex.) 2024 Feb;23(4):405-434
Dimerized sesquiterpenoid [4 + 2] adducts with ferroptosis-promoting activity from Inula britannica Linn.
Guo C, Geng HJ, Wang WJ, Liu YX, Deng L, Tian JM, Gao JM, Tang JJ
Phytochemistry 2024 Feb;218:113951
Phytochemistry 2024 Feb;218:113951
The PTB and PRR domains of numb regulate neurite outgrowth by influencing voltage-gated calcium channel expression and kinetics.
Wang G, Zhang Z, Li J, Han J, Lu C
Brain research bulletin 2024 Feb;207:110876
Brain research bulletin 2024 Feb;207:110876
Palbociclib sensitizes ER-positive breast cancer cells to fulvestrant by promoting the ubiquitin-mediated degradation of ER-α via SNHG17/Hippo-YAP axis.
Lei L, Huang Y, Shi L, Ye W, Lv X, Ying L, Yu X, Cheng SH, Zheng Y
Breast cancer research and treatment 2024 Feb;203(3):613-625
Breast cancer research and treatment 2024 Feb;203(3):613-625
Cholesterol-induced HRD1 reduction accelerates vascular smooth muscle cell senescence via stimulation of endoplasmic reticulum stress-induced reactive oxygen species.
Wang L, Wang M, Niu H, Zhi Y, Li S, He X, Ren Z, Wen S, Wu L, Wen S, Zhang R, Wen Z, Yang J, Zhang X, Chen Y, Qian X, Shi G
Journal of molecular and cellular cardiology 2024 Feb;187:51-64
Journal of molecular and cellular cardiology 2024 Feb;187:51-64
Haploinsufficiency of Lipin3 leads to hypertriglyceridemia and obesity by disrupting the expression and nucleocytoplasmic localization of Lipin1.
Wang F, Liu Y, Dong Y, Zhao M, Huang H, Jin J, Fan L, Xiang R
Frontiers of medicine 2024 Feb;18(1):180-191
Frontiers of medicine 2024 Feb;18(1):180-191
Photobiomodulation therapy alleviates repeated closed head injury-induced anxiety-like behaviors.
Chen Z, Li M, Wu C, Su Y, Feng S, Deng Q, Zou P, Liu TC, Duan R, Yang L
Journal of biophotonics 2024 Feb;17(2):e202300343
Journal of biophotonics 2024 Feb;17(2):e202300343
Downregulation of KCNMA1 in mice accelerates auditory hair cells senescence via ferroptosis.
Tang X, Zhong H, Xu C, Sun Y, Lou Y, Zhao Y, Liang Y, Guo X, Pan C, Sun J, Sun J
Neurobiology of aging 2024 Feb;134:115-125
Neurobiology of aging 2024 Feb;134:115-125
Data mining-guided alleviation of hyperuricemia by Paeonia veitchii Lynch through inhibition of xanthine oxidase and regulation of renal urate transporters.
Du J, Wang N, Yu D, He P, Gao Y, Tu Y, Li Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155305
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155305
Protective effect of TNFAIP3 on testosterone production in Leydig cells under an aging inflammatory microenvironment.
Xing D, Jin Y, Sun D, Liu Y, Cai B, Gao C, Cui Y, Jin B
Archives of gerontology and geriatrics 2024 Feb;117:105274
Archives of gerontology and geriatrics 2024 Feb;117:105274
CpxAR two-component system contributes to virulence properties of Cronobacter sakazakii.
Jin T, Zhan X, Pang L, Peng B, Zhang X, Zhu W, Yang B, Xia X
Food microbiology 2024 Feb;117:104393
Food microbiology 2024 Feb;117:104393
Astrocyte-Derived Extracellular Vesicular miR-143-3p Dampens Autophagic Degradation of Endothelial Adhesion Molecules and Promotes Neutrophil Transendothelial Migration after Acute Brain Injury.
Wu X, Liu H, Hu Q, Wang J, Zhang S, Cui W, Shi Y, Bai H, Zhou J, Han L, Li L, Wu Y, Luo J, Wang T, Guo C, Wang Q, Ge S, Qu Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(5):e2305339
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(5):e2305339
USF2 promotes autophagy and proliferation in chronic lymphocytic leukemia by inhibiting STUB1-induced NFAT5 ubiquitination.
Chen B, Zhao Y, Xu S, Jiang F, Nie Y, Tang A, Zhou Q
Annals of hematology 2024 Feb;103(2):533-544
Annals of hematology 2024 Feb;103(2):533-544
Chlamydia trachomatis upregulates lncRNA CYTOR to mediate autophagy through miR-206/MAPK1 axis.
Cheng S, Liu Y, He B, Zhang J, Yang Y, Wang X, Li Z
Pathogens and disease 2024 Feb 7;82
Pathogens and disease 2024 Feb 7;82
The Ameliorative Role of Lico A on Aflatoxin B(1)-Triggered Hepatotoxicity Partially by Activating Nrf2 Signal Pathway.
Lv H, Liu J, He Y, Xia S, Qiao C, Xu C
Journal of agricultural and food chemistry 2024 Feb 7;72(5):2741-2755
Journal of agricultural and food chemistry 2024 Feb 7;72(5):2741-2755
Suppression of HCN channels in the spinal dorsal horn restores KCC2 expression and attenuates diabetic neuropathic pain.
Ma Y, Chen J, Chen C, Wei B, Liu X
Neuroscience letters 2024 Feb 6;822:137626
Neuroscience letters 2024 Feb 6;822:137626
Methionine restriction of glioma does not induce MGMT and greatly improves temozolomide efficacy in an orthotopic nude-mouse model: A potential curable approach to a clinically-incurable disease.
Kubota Y, Aoki Y, Masaki N, Obara K, Hamada K, Han Q, Bouvet M, Tsunoda T, Hoffman RM
Biochemical and biophysical research communications 2024 Feb 5;695:149418
Biochemical and biophysical research communications 2024 Feb 5;695:149418
Design, synthesis and antitumor activity of 4-arylamine substituted pyrimidine derivatives as noncovalent EGFR inhibitors overcoming C797S mutation.
Zuo Y, Long Z, Li R, Le Y, Zhang S, He H, Yan L
European journal of medicinal chemistry 2024 Feb 5;265:116106
European journal of medicinal chemistry 2024 Feb 5;265:116106
Epigenetic drug screening for trophoblast syncytialization reveals a novel role for MLL1 in regulating fetoplacental growth.
Wu J, Qin C, Tian F, Liu X, Hu J, Wu F, Chen C, Lin Y
BMC medicine 2024 Feb 5;22(1):57
BMC medicine 2024 Feb 5;22(1):57
Wnt/β-catenin signalling activates IMPDH2-mediated purine metabolism to facilitate oxaliplatin resistance by inhibiting caspase-dependent apoptosis in colorectal cancer.
Huang Y, Chan S, Chen S, Liu X, Li M, Zheng L, Dong Z, Yang Z, Liu Z, Zhou D, Zhang X, Zhang B
Journal of translational medicine 2024 Feb 3;22(1):133
Journal of translational medicine 2024 Feb 3;22(1):133
Loss of Slc39a12 in hippocampal neurons is responsible for anxiety-like behavior caused by temporomandibular joint osteoarthritis.
Shen Z, Fan C, Ding C, Xu M, Wu X, Wang Y, Xing T
Heliyon 2024 Feb 29;10(4):e26271
Heliyon 2024 Feb 29;10(4):e26271
Analysis of the role of PANoptosis in seizures via integrated bioinformatics analysis and experimental validation.
Liu Y, Chang Y, Jiang X, Mei H, Cao Y, Wu D, Xie R, Jiang W, Vasquez E, Wu Y, Lin S, Cao Y
Heliyon 2024 Feb 29;10(4):e26219
Heliyon 2024 Feb 29;10(4):e26219
TsMS combined with EA promotes functional recovery and axonal regeneration via mediating the miR-539-5p/Sema3A/PlexinA1 signalling axis in sciatic nerve-injured rats.
Wang X, Hu S, Ouyang S, Pan X, Fu Y, Chen X, Wu S
Neuroscience letters 2024 Feb 28;824:137691
Neuroscience letters 2024 Feb 28;824:137691
Dendrobine Ameliorates Alzheimer's Disease-like Pathology and Cognitive Decline in 3 × Tg-AD Mice.
Zhang W, Huang J, Shi J
Brain sciences 2024 Feb 28;14(3)
Brain sciences 2024 Feb 28;14(3)
An Inulin-Type Fructan CP-A from Codonopsis pilosula Alleviated 5-Fluorouracil-Induced Intestinal Mucositis via the ERK/MLCK/MLC2 Pathway and Regulation of Gut Microbiota.
Zhou J, Li D, Wang J, Cheng Z, Wang C, Zhang X, Xu X, Gao J
Pharmaceuticals (Basel, Switzerland) 2024 Feb 26;17(3)
Pharmaceuticals (Basel, Switzerland) 2024 Feb 26;17(3)
VX-509 attenuates the stemness characteristics of colorectal cancer stem-like cells by regulating the epithelial-mesenchymal transition through Nodal/Smad2/3 signaling.
Yuan Y, Zhang XF, Li YC, Chen HQ, Wen T, Zheng JL, Zhao ZY, Hu QY
World journal of stem cells 2024 Feb 26;16(2):207-227
World journal of stem cells 2024 Feb 26;16(2):207-227
SLC25A17 inhibits autophagy to promote triple-negative breast cancer tumorigenesis by ROS-mediated JAK2/STAT3 signaling pathway.
Zhou H, Li J, He Y, Xia X, Liu J, Xiong H
Cancer cell international 2024 Feb 24;24(1):85
Cancer cell international 2024 Feb 24;24(1):85
ACACA reduces lipid accumulation through dual regulation of lipid metabolism and mitochondrial function via AMPK- PPARα- CPT1A axis.
Dong J, Li M, Peng R, Zhang Y, Qiao Z, Sun N
Journal of translational medicine 2024 Feb 23;22(1):196
Journal of translational medicine 2024 Feb 23;22(1):196
Discovery of a Novel Series of Homo sapiens Caseinolytic Protease P Agonists for Colorectal Adenocarcinoma Treatment via ATF3-Dependent Integrated Stress Response.
Zhang J, Qiu Z, Liu S, Huang J, Luo B, Sui J, Dai Z, Xiang X, Yang T, Luo Y
Journal of medicinal chemistry 2024 Feb 22;67(4):2812-2836
Journal of medicinal chemistry 2024 Feb 22;67(4):2812-2836
The Parkinson's disease related mutant VPS35 (D620N) amplifies the LRRK2 response to endolysosomal stress.
McCarron KR, Elcocks H, Mortiboys H, Urbé S, Clague MJ
The Biochemical journal 2024 Feb 21;481(4):265-278
The Biochemical journal 2024 Feb 21;481(4):265-278
Long noncoding RNA TMPO-AS1 accelerates glycolysis by regulating the miR-1270/PKM2 axis in colorectal cancer.
Jin Y, Jiang A, Sun L, Lu Y
BMC cancer 2024 Feb 21;24(1):238
BMC cancer 2024 Feb 21;24(1):238
Prognosis and biological function of SGOL1 in clear cell renal cell carcinoma: a multiomics analysis.
Yang Z, Jiang Y, Wang L, Yu B, Cai H, Fan J, Zhang M
BMC medical genomics 2024 Feb 21;17(1):60
BMC medical genomics 2024 Feb 21;17(1):60
Endothelial Robo4 suppresses endothelial-to-mesenchymal transition induced by irradiation and improves hematopoietic reconstitution.
Adzraku SY, Cao C, Zhou Q, Yuan K, Hao X, Li Y, Yuan S, Huang Y, Xu K, Qiao J, Ju W, Zeng L
Cell death & disease 2024 Feb 21;15(2):159
Cell death & disease 2024 Feb 21;15(2):159
The microbial metabolite urolithin A reduces Clostridioides difficile toxin expression and toxin-induced epithelial damage.
Ghosh S, Erickson D, Chua MJ, Collins J, Jala VR
mSystems 2024 Feb 20;9(2):e0125523
mSystems 2024 Feb 20;9(2):e0125523
Complement components regulates ferroptosis in CVB3 viral myocarditis by interatction with TFRC.
Yi L, Yang Y, Hu Y, Wu Z, Kong M, Zuoyuan B, Xin X, Yang Z
Free radical biology & medicine 2024 Feb 20;212:349-359
Free radical biology & medicine 2024 Feb 20;212:349-359
AURKA Enhances the Glycolysis and Development of Ovarian Endometriosis Through ERβ.
Sun Y, Zhang S, Zhang X, Li G, Sun F, Wang M, Ren C, Jiang A, Yang T
Endocrinology 2024 Feb 20;165(4)
Endocrinology 2024 Feb 20;165(4)
Galectin-3 is involved in inflammation and fibrosis in arteriogenic erectile dysfunction via the TLR4/MyD88/NF-κB pathway.
Wang G, Li R, Feng C, Li K, Liu S, Fu Q
Cell death discovery 2024 Feb 20;10(1):92
Cell death discovery 2024 Feb 20;10(1):92
LncRNA RPARP-AS1 promotes the progression of osteosarcoma cells through regulating lipid metabolism.
Cai F, Liu L, Bo Y, Yan W, Tao X, Peng Y, Zhang Z, Liao Q, Yi Y
BMC cancer 2024 Feb 2;24(1):166
BMC cancer 2024 Feb 2;24(1):166
KIF18A inactivates hepatic stellate cells and alleviates liver fibrosis through the TTC3/Akt/mTOR pathway.
Zhang H, Xia T, Xia Z, Zhou H, Li Z, Wang W, Zhai X, Jin B
Cellular and molecular life sciences : CMLS 2024 Feb 19;81(1):96
Cellular and molecular life sciences : CMLS 2024 Feb 19;81(1):96
In Vitro Insights into the Role of 7,8-Epoxy-11-Sinulariolide Acetate Isolated from Soft Coral Sinularia siaesensis in the Potential Attenuation of Inflammation and Osteoclastogenesis.
Ke LM, Yu DD, Su MZ, Cui L, Guo YW
Marine drugs 2024 Feb 19;22(2)
Marine drugs 2024 Feb 19;22(2)
A Mixture of Formic Acid, Benzoic Acid, and Essential Oils Enhanced Growth Performance via Modulating Nutrient Uptake, Mitochondrion Metabolism, and Immunomodulation in Weaned Piglets.
Wang X, Deng T, Zhou X, Chu L, Zeng X, Zhang S, Guan W, Chen F
Antioxidants (Basel, Switzerland) 2024 Feb 19;13(2)
Antioxidants (Basel, Switzerland) 2024 Feb 19;13(2)
Solobacterium moorei promotes the progression of adenomatous polyps by causing inflammation and disrupting the intestinal barrier.
Yu S, Wang X, Li Z, Jin D, Yu M, Li J, Li Y, Liu X, Zhang Q, Liu Y, Liu R, Wang X, Fang B, Zhang C, Wang R, Ren F
Journal of translational medicine 2024 Feb 17;22(1):169
Journal of translational medicine 2024 Feb 17;22(1):169
The neuroprotective effect of LCZ696 on methamphetamine-induced cognitive impairment in mice.
Qian L, Ruan Y, Gong X, Yu Z, Lin S, Li X, Shen Y, Luo H, Si Z, Liu Y
Neuroscience letters 2024 Feb 16;823:137630
Neuroscience letters 2024 Feb 16;823:137630
NLRP3-GSDMD-dependent IL-1β Secretion from Microglia Mediates Learning and Memory Impairment in a Chronic Intermittent Hypoxia-induced Mouse Model.
Li C, Zhao Z, Jin J, Zhao C, Zhao B, Liu Y
Neuroscience 2024 Feb 16;539:51-65
Neuroscience 2024 Feb 16;539:51-65
Protein phosphatase 1 regulatory subunit 15 A promotes translation initiation and induces G2M phase arrest during cuproptosis in cancers.
Liu C, Chen L, Cong Y, Cheng L, Shuai Y, Lv F, Chen K, Song Y, Xing Y
Cell death & disease 2024 Feb 16;15(2):149
Cell death & disease 2024 Feb 16;15(2):149
Potential Therapeutic Effects of Bifidobacterium breve MCC1274 on Alzheimer's Disease Pathologies in App(NL-G-F) Mice.
Abdelhamid M, Jung CG, Zhou C, Inoue R, Chen Y, Sento Y, Hida H, Michikawa M
Nutrients 2024 Feb 15;16(4)
Nutrients 2024 Feb 15;16(4)
Exploring the therapeutic mechanisms and prognostic targets of Biochanin A in glioblastoma via integrated computational analysis and in vitro experiments.
Ge W, Yuan G, Wang D, Dong L
Scientific reports 2024 Feb 15;14(1):3783
Scientific reports 2024 Feb 15;14(1):3783
Potential effects of different cell death inhibitors in protecting against ischemia-reperfusion injury in steatotic liver.
Junzhe J, Meng L, Weifan H, Min X, Jiacheng L, Yihan Q, Ke Z, Fang W, Dongwei X, Hailong W, Xiaoni K
International immunopharmacology 2024 Feb 15;128:111545
International immunopharmacology 2024 Feb 15;128:111545
E. Coli LPS-induced calcium signaling regulates the expression of hypoxia-inducible factor 1α in periodontal ligament fibroblasts in a non-hypoxia-dependent manner.
Yang X, Cai X, Lin J, Zheng Y, Liao Z, Lin W, He X, Zhang Y, Ren X, Liu C
International immunopharmacology 2024 Feb 15;128:111418
International immunopharmacology 2024 Feb 15;128:111418
Severe inflammation in C57/BL6 mice leads to prolonged cognitive impairment by initiating the IL-1β/TRPM2 pathway.
Yang Y, Yao Z, Wang H, Jia S, Wang M, Wang S, Yun D
International immunopharmacology 2024 Feb 15;128:111380
International immunopharmacology 2024 Feb 15;128:111380
Intermittent Hypobaric Hypoxia Ameliorates Autistic-Like Phenotypes in Mice.
Pan YD, Zhang Y, Zheng WY, Zhu MZ, Li HY, Ouyang WJ, Wen QQ, Zhu XH
The Journal of neuroscience : the official journal of the Society for Neuroscience 2024 Feb 14;44(7)
The Journal of neuroscience : the official journal of the Society for Neuroscience 2024 Feb 14;44(7)
High expression of TBRG4 in relation to unfavorable outcome and cell ferroptosis in hepatocellular carcinoma.
Tao S, Cui D, Cheng H, Liu X, Jiang Z, Chen H, Gao Y
BMC cancer 2024 Feb 12;24(1):194
BMC cancer 2024 Feb 12;24(1):194
Pharmacological effects and mechanism of Maxing Shigan decoction in the treatment of Pseudomonas aeruginosa pneumonia.
Xu Y, Bao L, Cao S, Pang B, Zhang J, Zhang Y, Chen M, Wang Y, Sun Q, Zhao R, Guo S, Sun J, Cui X
Journal of ethnopharmacology 2024 Feb 10;320:117424
Journal of ethnopharmacology 2024 Feb 10;320:117424
Sasanquasaponin from Camellia oleifera Abel Exerts an Anti-Inflammatory Effect in RAW 264.7 Cells via Inhibition of the NF-κB/MAPK Signaling Pathways.
Zhao Y, Zhao N, Kollie L, Yang D, Zhang X, Zhang H, Liang Z
International journal of molecular sciences 2024 Feb 10;25(4)
International journal of molecular sciences 2024 Feb 10;25(4)
AAA237, an SKP2 inhibitor, suppresses glioblastoma by inducing BNIP3-dependent autophagy through the mTOR pathway.
Zhang Y, Li W, Yang Y, Zhang S, Yang H, Hao Y, Fang X, Du G, Shi J, Wu L, Wang J
Cancer cell international 2024 Feb 10;24(1):69
Cancer cell international 2024 Feb 10;24(1):69
Antitumoral Potential of the Histone Demethylase Inhibitor GSK-J4 in Retinoblastoma.
Zhang Y, Wu W, Xu C, Yang H, Huang G
Investigative ophthalmology & visual science 2024 Feb 1;65(2):34
Investigative ophthalmology & visual science 2024 Feb 1;65(2):34
β-Lapachone induces ferroptosis of colorectal cancer cells via NCOA4-mediated ferritinophagy by activating JNK pathway.
Zhao L, Miao H, Quan M, Wang S, Zhang Y, Zhou H, Zhang X, Lin Z, Piao J
Chemico-biological interactions 2024 Feb 1;389:110866
Chemico-biological interactions 2024 Feb 1;389:110866
Systematic pan-cancer analysis of RNF186 with potential implications in progression and prognosis in human cancer.
Hu Y, Jiang N, Wang X, Wu X, Bo J, Chen Y, Zeng Y, Wei X, Zhang H, Li M
Life sciences 2024 Feb 1;338:122389
Life sciences 2024 Feb 1;338:122389
Testosterone reduces hippocampal synaptic damage in an androgen receptor-independent manner.
Zhang Y, Chen M, Chen H, Mi S, Wang C, Zuo H, Song L, Du J, Cui H, Li S
The Journal of endocrinology 2024 Feb 1;260(2)
The Journal of endocrinology 2024 Feb 1;260(2)
Identification of DNA methylation biomarkers for evaluating cardiovascular disease risk from epigenome profiles altered by low-dose ionizing radiation.
Park J, Lee HJ, Han YK, Kang K, Yi JM
Clinical epigenetics 2024 Feb 1;16(1):19
Clinical epigenetics 2024 Feb 1;16(1):19
Therapeutic potential of Lacticaseibacillus rhamnosus grx10 and its derived postbiotic through gut microbiota and MAPK/MLCK/MLC pathway-mediated intestinal barrier repairment in ulcerative colitis.
Ye H, Liu X, Guan K, Ma Y, Liu R, Liu Y, Lv X, Wang R, Li Q
Journal of food science 2024 Dec;89(12):10035-10052
Journal of food science 2024 Dec;89(12):10035-10052
ALDH2 attenuates radiation-induced lung injury by inhibiting ROS and epithelial-mesenchymal transition mediated by the TGF-β1/Smad pathway.
Li E, Huang J, Huang J, Zhang F, Li C, Xia M, Li Z, Peng B, Liu Y, Ma J, Lei M
Pulmonary pharmacology & therapeutics 2024 Dec;87:102334
Pulmonary pharmacology & therapeutics 2024 Dec;87:102334
Compromised cell competition exhausts neural stem cells pool.
Li C, Zhang M, Du Y, Liu S, Li D, Zhang S, Ji F, Zhang J, Jiao J
Cell proliferation 2024 Dec;57(12):e13710
Cell proliferation 2024 Dec;57(12):e13710
MiR-143-5p regulates the proangiogenic potential of human dental pulp stem cells by targeting HIF-1α/RORA under hypoxia: A laboratory investigation in pulp regeneration.
Meng Z, Zhong X, Liang D, Ma X, Chen W, He X
International endodontic journal 2024 Dec;57(12):1802-1818
International endodontic journal 2024 Dec;57(12):1802-1818
Astrocyte-neuron crosstalk through extracellular vesicle-shuttled miRNA-382-5p promotes traumatic brain injury.
Hu Q, Wu X, Guo C, Wang T, Guo H, Wang J, Wang B, Cui W, Bai H, Zhou J, Li L, Han L, Cao L, Ge S, Gao G, Wang T, Wu Z, Guo W, Qu Y, Feng J, Liu H
Experimental & molecular medicine 2024 Dec;56(12):2642-2658
Experimental & molecular medicine 2024 Dec;56(12):2642-2658
Multi-omics profiling highlights karyopherin subunit alpha 2 as a promising biomarker for prognosis and immunotherapy respond in pediatric and adult adrenocortical carcinoma.
Chen Y, Fang S, Zhong C, Mo S, Shi Y, Ling X, Liu F, Zhong W, Deng J, Dong Z, Chen J, Lu J
Annals of medicine 2024 Dec;56(1):2397092
Annals of medicine 2024 Dec;56(1):2397092
Shikonin from lithospermum erythrorhizon induces pyroptosis in trophoblast cells by activating the CTSB-NLRP3 inflammasome.
Zeng F, Lai Y, Huang Y, Zhu F, Gao J, Chen Z, Zeng L, Feng M, Qiu P, Yuan S, Deng G
Annals of medicine 2024 Dec;56(1):2394584
Annals of medicine 2024 Dec;56(1):2394584
Curcumin pretreatment attenuates myocardial ischemia/reperfusion injury by inhibiting ferroptosis, autophagy and apoptosis via HES1.
Yuan Y, Huang H, Hu T, Zou C, Qiao Y, Fang M, Liu J, Lai S
International journal of molecular medicine 2024 Dec;54(6)
International journal of molecular medicine 2024 Dec;54(6)
Regulation of lipid metabolism in grass carp primary hepatocytes by exosomes derived from fatty hepatocytes though GRP78.
Yang L, Lu R, Cao K, Chen M, Xu X, Cao X, Zhang Y, Nie G
Fish physiology and biochemistry 2024 Dec;50(6):2287-2299
Fish physiology and biochemistry 2024 Dec;50(6):2287-2299
Tripartite-motif 3 represses ovarian cancer progression by downregulating lactate dehydrogenase A and inhibiting AKT signaling.
Cong Y, Cui X, Shi Y, Pan X, Huang K, Geng Z, Xu P, Ge L, Zhu J, Xu J, Jia X
Molecular and cellular biochemistry 2024 Dec;479(12):3405-3424
Molecular and cellular biochemistry 2024 Dec;479(12):3405-3424
Melatonin antagonizes oxidative stress-induced apoptosis in retinal ganglion cells through activating the thioredoxin-1 pathway.
Gao S, Cheng Q, Hu Y, Fan X, Liang C, Niu C, Kang Q, Wei T
Molecular and cellular biochemistry 2024 Dec;479(12):3393-3404
Molecular and cellular biochemistry 2024 Dec;479(12):3393-3404
Targeting CA9 restricts pancreatic cancer progression through pH regulation and ROS production.
Yang J, Tong X, Wang W, Yu X, Xu J, Shi S
Cellular oncology (Dordrecht, Netherlands) 2024 Dec;47(6):2367-2382
Cellular oncology (Dordrecht, Netherlands) 2024 Dec;47(6):2367-2382
USP28 promotes tumor progression and glycolysis by stabilizing PKM2/Hif1-α in cholangiocarcinoma.
Qiao Q, Wang J, Liu S, Chang J, Zhou T, Li C, Zhang Y, Jiang W, Chen Y, Xu X, Wu M, Li X
Cellular oncology (Dordrecht, Netherlands) 2024 Dec;47(6):2217-2231
Cellular oncology (Dordrecht, Netherlands) 2024 Dec;47(6):2217-2231
TXNIP deficiency attenuates renal fibrosis by modulating mTORC1/TFEB-mediated autophagy in diabetic kidney disease.
Du Y, Wu M, Song S, Bian Y, Shi Y
Renal failure 2024 Dec;46(1):2338933
Renal failure 2024 Dec;46(1):2338933
Decoction of Yougui Wan combined with Wuzi Yanzong Wan ameliorates thin endometrium in a mouse model.
Zhou X, Xiang J, Su A
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 2024 Dec;44(1):2391062
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 2024 Dec;44(1):2391062
Metformin enhances epithelial cell growth inhibition via the protein kinase-insulin-like growth factor binding protein-1 pathway.
Shao X, Li C, Liang J, Changzhong L
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 2024 Dec;44(1):2321651
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 2024 Dec;44(1):2321651
Mesenchymal stem cells may alleviate angiotensin II-induced myocardial fibrosis and hypertrophy by upregulating SFRS3 expression.
Gu L, Wan X, Liu Y, Gong Z, Huang R, Shi Y, Liu H
Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 2024 Dec;43(12):645-656
Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 2024 Dec;43(12):645-656
Intraoperative blood auto-transfusion restrained the malignancy of Liver Cancer via regulating functions of tumor cells and Kuffer cells.
Yao N, Wu M, You L, Xu J, Liu T, Wang J, Li Z, Sun Y, Guo J
Biotechnology & genetic engineering reviews 2024 Dec;40(4):4394-4406
Biotechnology & genetic engineering reviews 2024 Dec;40(4):4394-4406
Efficient and robust reverse genetics system for bovine rotavirus generation and its application for antiviral screening.
Qin SK, Li KH, Liu BJ, Cao C, Yu DB, Jiang ZG, Wang J, Han YX, Wang F, Qi YL, Sun C, Yu L, Chang JT, Yin X
Virologica Sinica 2024 Dec;39(6):917-928
Virologica Sinica 2024 Dec;39(6):917-928
Pachymic acid ameliorates bleomycin-induced pulmonary fibrosis through inhibiting endoplasmic reticulum stress in rats.
Li L, Jin RJ, Ji L
Environmental toxicology 2024 Dec;39(12):5382-5390
Environmental toxicology 2024 Dec;39(12):5382-5390
Design, synthesis, and evaluation of cyclic C7-bridged monocarbonyl curcumin analogs containing an o-methoxy phenyl group as potential agents against gastric cancer.
Gan X, Wu Y, Zhu M, Liu B, Kong M, Xi Z, Li K, Wang H, Su T, Yao J, Khushafah F, Yi B, Wang J, Li W, Wu J
Journal of enzyme inhibition and medicinal chemistry 2024 Dec;39(1):2314233
Journal of enzyme inhibition and medicinal chemistry 2024 Dec;39(1):2314233
Mesenchymal stem cell-loaded hydrogel to inhibit inflammatory reaction in surgical brain injury via mitochondria transfer.
Wang Y, Yang X, Liu M, Yan Y, Kong F, Wang J, Zhang Z, Chen Y, Chen L, Liang Z, Peng X, Liu F
Journal of controlled release : official journal of the Controlled Release Society 2024 Dec;376:231-240
Journal of controlled release : official journal of the Controlled Release Society 2024 Dec;376:231-240
Novel benzothiazole/benzothiazole thiazolidine-2,4-dione derivatives as potential FOXM1 inhibitors: In silico, synthesis, and in vitro studies.
Abusharkh KAN, Comert Onder F, Çınar V, Onder A, Sıkık M, Hamurcu Z, Ozpolat B, Ay M
Archiv der Pharmazie 2024 Dec;357(12):e2400504
Archiv der Pharmazie 2024 Dec;357(12):e2400504
In situ customized apolipoprotein B48-enriched protein corona enhances oral gene delivery of chitosan-based nanoparticles.
Lin Z, Li S, Wu Q, Qu H, Shi X, Wang K, Tang C, Yin C
Biomaterials 2024 Dec;311:122704
Biomaterials 2024 Dec;311:122704
A Novel Compound Ligusticum Cycloprolactam Alleviates Neuroinflammation After Ischemic Stroke via the FPR1/NLRP3 Signaling Axis.
Gao J, Su G, Liu J, Song J, Chen W, Chai M, Xie X, Wang M, Liu J, Zhang Z
CNS neuroscience & therapeutics 2024 Dec;30(12):e70158
CNS neuroscience & therapeutics 2024 Dec;30(12):e70158
The effects of Cordyceps polysaccharides on ischemic brain injury in rats via intervening with IL-23/IL-17 axis and the intestinal barrier.
Jiang Y, Liao Y, Liu Z, Zhou M, Wang H, Qi H, Sun S, Xi S, Tang Y
International journal of biological macromolecules 2024 Dec;283(Pt 2):137526
International journal of biological macromolecules 2024 Dec;283(Pt 2):137526
miR-221-5p_R-4 regulates internalized trehalose-induced autophagy by targeting NRBF2 in porcine granulosa cells.
Lv J, Liu G, Gao H, He Y, Tang X, Wang Z, Sun K, Bayazitova K, Jiang Z
International journal of biological macromolecules 2024 Dec;282(Pt 2):136718
International journal of biological macromolecules 2024 Dec;282(Pt 2):136718
RVG-peptide-camouflaged iron-coordinated engineered polydopamine nanoenzyme with ROS scavenging and inhibiting inflammatory response for ischemic stroke therapy.
Liu H, Zhuo R, Zou C, Xu S, Cai X, Ge Y, Liu G, Wu C, Dai C, Li J, Fan Z, Yang L, Li Y
International journal of biological macromolecules 2024 Dec;282(Pt 1):136778
International journal of biological macromolecules 2024 Dec;282(Pt 1):136778
Indole-3-Carboxaldehyde Inhibits Inflammatory Response and Lipid Accumulation in Macrophages Through the miR-1271-5p/HDAC9 Pathway.
Luo W, Meng J, Yu XH, Zhang ZZ, Wang G, He J
Journal of cellular and molecular medicine 2024 Dec;28(24):e70263
Journal of cellular and molecular medicine 2024 Dec;28(24):e70263
Benzaldehyde stimulates autophagy via the sonic hedgehog signaling pathway in mouse brain astrocytes after treatment with Angiostrongylus cantonensis excretory-secretory products.
Chen KY, Cheng CJ, Chang YT, Lin YH, Huang YH, Lin SY, Wang LC, Jhan KY, Chiu CH
International journal for parasitology. Drugs and drug resistance 2024 Dec;26:100560
International journal for parasitology. Drugs and drug resistance 2024 Dec;26:100560
Glycogenesis and glyconeogenesis from glutamine, lactate and glycerol support human macrophage functions.
Jeroundi N, Roy C, Basset L, Pignon P, Preisser L, Blanchard S, Bocca C, Abadie C, Lalande J, Gueguen N, Mabilleau G, Lenaers G, Moreau A, Copin MC, Tcherkez G, Delneste Y, Couez D, Jeannin P
EMBO reports 2024 Dec;25(12):5383-5407
EMBO reports 2024 Dec;25(12):5383-5407
Tanshinone IIA Exerts Cardioprotective Effects Through Improving Gut-Brain Axis Post-Myocardial Infarction.
Zhu T, Chen J, Zhang M, Tang Z, Tong J, Hao X, Li H, Xu J, Yang J
Cardiovascular toxicology 2024 Dec;24(12):1317-1334
Cardiovascular toxicology 2024 Dec;24(12):1317-1334
Activation of ferritin light chain (FTL) by transcription factor salmonella pathogenicity island 1 modulates glycolysis to drive metastasis of ovarian cancer cells.
Li C, Yang Y, Lin Y, Lian Y, Pan D, Lin L, Li L
Expert review of anticancer therapy 2024 Dec;24(12):1271-1282
Expert review of anticancer therapy 2024 Dec;24(12):1271-1282
Activation of the γ-secretase/NICD-PXR/Notch pathway induces Taxol resistance in triple-negative breast cancer.
Wang ZJ, Zhan XY, Ma LY, Yao K, Dai HY, Kumar Santhanam R, Zhou MS, Jia H
Biochemical pharmacology 2024 Dec;230(Pt 2):116577
Biochemical pharmacology 2024 Dec;230(Pt 2):116577
Skin as outermost immune organ of vertebrates that elicits robust early immune responses after immunization with glycoprotein of spring viraemia of carp virus.
Zhao Z, Zhao L, Wei XF, Jia YJ, Zhu B
PLoS pathogens 2024 Dec;20(12):e1012744
PLoS pathogens 2024 Dec;20(12):e1012744
Dual-activity nanozyme as an oxygen pump to alleviate tumor hypoxia and enhance photodynamic/ NIR-II photothermal therapy for sniping oral squamous cell carcinoma.
Li X, Hao M, Liu A, Li L, Nešić MD, Yang B, Liu W, Lin Q
Acta biomaterialia 2024 Dec;190:476-487
Acta biomaterialia 2024 Dec;190:476-487
Molecular mechanism through which Tripterygium hypoglaucum (Lévl.) Hutch alleviates psoriasis.
Sun Y, Wang J, Hu P, Tang Y, Wang Y, Ye J, Yang X, Yin J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Dec;181:117647
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Dec;181:117647
Deciphering the therapeutic potential of Myeloid-Specific JAK2 inhibition in acute respiratory distress syndrome.
Gao S, Li W, Huang Z, Deiuliis JA, Braunstein Z, Liu X, Li X, Kosari M, Chen J, Min X, Yang H, Gong Q, Liu Z, Wei Y, Zhang Z, Dong L, Zhong J
Mucosal immunology 2024 Dec;17(6):1273-1284
Mucosal immunology 2024 Dec;17(6):1273-1284
Integrin αVβ3 mediates porcine deltacoronavirus infection and inflammatory response through activation of the FAK-PI3K-AKT-nf-κB signalling pathway.
Jin X, Wu X, Li Z, Hu Y, Xia L, Zu S, Zhang G, Hu H
Virulence 2024 Dec;15(1):2407847
Virulence 2024 Dec;15(1):2407847
Green tea polyphenol alleviates silica particle-induced lung injury by suppressing IL-17/NF-κB p65 signaling-driven inflammation.
Xu Y, Ding Q, Xie Y, Zhang Q, Zhou Y, Sun H, Qian R, Wang L, Chen X, Gao Y, Yao Y, Xiao Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156238
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156238
Icariin ameliorates Coxsackievirus B3-induced viral myocarditis by modulating the S100 calcium binding protein A6/β-catenin/c-Myc signaling pathway.
Tian H, Pan Q, Wu J, Liao J, Wan Y, Pei K, Liu Q, Zeng L, Cao Y, Shi Q, Kuang N, Sun L, Yu X, Huang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156214
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156214
Huangqi-Danshen decoction improves heart failure by regulating pericardial adipose tissue derived extracellular vesicular miR-27a-3p to activate AMPKα2 mediated mitophagy.
Chen Z, Zhang M, Xu Q, Lu P, Liu M, Yin R, Liu X, Dai Y, Gao X, Gong J, Zhang S, Wang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156187
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156187
4-Hydroxydictyolactone alleviates cerebral ischemia injury by regulating neuroinflammation and autophagy via AMPK signaling pathway.
Qi Y, Zhu H, Chen Y, Zhang Y, Jin S, Xu X, Ma X, Chen L, Zhao M, Zhu H, Yan P
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156157
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156157
Hesperidin alleviated dendritic spines through inhibiting ferritinophagy via HERC2-NCOA4 ubiquitination in CUMS mice.
Zhang M, Cui Y, Jia R, Cai Z, Shen Y, Yu W, Pang Z, Ding S, Gao X, Huang Y, Song M, Lou Y, Ye F, Ao H, Zhu A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156132
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156132
New finding based on Comparative Toxicogenomics Database: Hepatic YY1 mediates drug-induced liver injury.
Zhao JQ, Sun Y, Yang LL, Long J, Jiang Y, Li HJ
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156102
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156102
A multi-omic analysis reveals that Gamabufotalin exerts anti-hepatocellular carcinoma effects by regulating amino acid metabolism through targeting STAMBPL1.
Zheng P, Xu D, Cai Y, Zhu L, Xiao Q, Peng W, Chen B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156094
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156094
Investigating the effects of COVID-19 on sperm in male smokers: A prospective integrated proteomic and metabolomic study.
Wang C, Zhang J, Gao F, Zheng M, Fu X, Yang K
Reproductive toxicology (Elmsford, N.Y.) 2024 Dec;130:108734
Reproductive toxicology (Elmsford, N.Y.) 2024 Dec;130:108734
Identification of cepharanthine as an effective inhibitor of African swine fever virus replication.
Qi C, Lee J, Zhang Y, Chen H, Lv J, Wang Z, Li J, Wu X, Jung YS, Wang Z, Qian Y
Emerging microbes & infections 2024 Dec;13(1):2429624
Emerging microbes & infections 2024 Dec;13(1):2429624
MEK inhibitor trametinib combined with PI3K/mTOR inhibitor BEZ-235 as an effective strategy against NSCLC through impairment of glucose metabolism.
Liu Y, Qing B, Ke W, Wang M
Cellular signalling 2024 Dec;124:111415
Cellular signalling 2024 Dec;124:111415
Design and characterization of defined alpha-helix mini-proteins with intrinsic cell permeability.
Chen XC, Kong XW, Chen P, Li ZQ, Huang N, Zhao Z, Yang J, Zhao GX, Mo Q, Lu YT, Huang XM, Feng GK, Zeng MS
Computational biology and chemistry 2024 Dec;113:108271
Computational biology and chemistry 2024 Dec;113:108271
Parkinson Disease -Targeted Nanocapsules for Synergistic Treatment: Combining Dopamine Replacement and Neuroinflammation Mitigation.
Liu Z, Xiang S, Chen B, Li J, Zhu D, Xu H, Hu S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(46):e2404717
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(46):e2404717
Proteogenomic Landscape of Breast Ductal Carcinoma Reveals Tumor Progression Characteristics and Therapeutic Targets.
Xu G, Yu J, Lyu J, Zhan M, Xu J, Huang M, Zhao R, Li Y, Zhu J, Feng J, Tan S, Ran P, Su Z, Liu X, Zhao J, Zhang H, Xu C, Chang J, Hou Y, Ding C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(46):e2401041
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(46):e2401041
Up-regulated Lnc BTU promotes the production of duck plague virus DNA polymerase and inhibits the activation of JAK-STAT pathway to facilitate duck plague virus replication.
Luo N, Cheng A, Wang M, Chen S, Liu M, Zhu D, Wu Y, Tian B, Ou X, Huang J, Wu Z, Yin Z, Jia R
Poultry science 2024 Dec;103(12):104238
Poultry science 2024 Dec;103(12):104238
Adropin regulates macrophage phenotype via PPARγ signalling: A preliminary study of adropin and Crohn's disease.
Zeng L, Chen J, Xie H, Liu W, Wang C
Scandinavian journal of immunology 2024 Dec;100(6):e13415
Scandinavian journal of immunology 2024 Dec;100(6):e13415
Pericancerous cross-presentation to cytotoxic T lymphocytes impairs immunotherapeutic efficacy in hepatocellular carcinoma.
Huang CX, Lao XM, Wang XY, Ren YZ, Lu YT, Shi W, Wang YZ, Wu CY, Xu L, Chen MS, Gao Q, Liu L, Wei Y, Kuang DM
Cancer cell 2024 Dec 9;42(12):2082-2097.e10
Cancer cell 2024 Dec 9;42(12):2082-2097.e10
Targeting the immune privilege of tumor-initiating cells to enhance cancer immunotherapy.
Yang C, Geng H, Yang X, Ji S, Liu Z, Feng H, Li Q, Zhang T, Zhang S, Ma X, Zhu C, Xu N, Xia Y, Li Y, Wang H, Yu C, Du S, Miao B, Xu L, Wang H, Cao Y, Li B, Zhu L, Tang X, Zhang H, Zhu C, Huang Z, Leng C, Hu H, Chen X, Yuan S, Jin G, Bernards R, Sun C, Zheng Q, Qin W, Gao Q, Wang C
Cancer cell 2024 Dec 9;42(12):2064-2081.e19
Cancer cell 2024 Dec 9;42(12):2064-2081.e19
Magnesium-Based Composite Calcium Phosphate Cement Promotes Osteogenesis and Angiogenesis for Minipig Vertebral Defect Regeneration.
Tian F, Zhao Y, Wang Y, Xu H, Liu Y, Liu R, Li H, Ning R, Wang C, Gao X, Luo R, Jia S, Zhu L, Hao D
ACS biomaterials science & engineering 2024 Dec 9;10(12):7577-7593
ACS biomaterials science & engineering 2024 Dec 9;10(12):7577-7593
Exercise preconditioning mitigates Ischemia-Reperfusion injury in rats by enhancing mitochondrial respiration.
Liang R, Hou X, Zhou D, Zhu L, Teng L, Song W, Tang Q
Neuroscience 2024 Dec 6;562:64-74
Neuroscience 2024 Dec 6;562:64-74
Gypenoside A-loaded mPEG-PLGA nanoparticles ameliorate high-glucose-induced retinal microvasculopathy by inhibiting ferroptosis.
Chen Q, Qiu FS, Xie W, Yu WY, Su ZA, Qin GM, Kang YK, Jiang SL, Yu CH
International journal of pharmaceutics 2024 Dec 5;666:124758
International journal of pharmaceutics 2024 Dec 5;666:124758
A tiered toxicity testing strategy for assessing early life stage toxicity in estuarine fish (Mugilogobius chulae): A case study on tris (1-chloro-2-propyl) phosphate ester.
Ren J, Peng Y, She L, Yan L, Li J, Gao C, Wang C, Wang Y, Nie X, Zhang X
Journal of hazardous materials 2024 Dec 5;480:136108
Journal of hazardous materials 2024 Dec 5;480:136108
Investigating the potential risk of cadmium exposure on seizure severity and anxiety-like behaviors through the ferroptosis pathway in epileptic mice: An integrated multi-omics approach.
Chang Y, Jiang X, Dou J, Xie R, Zhao W, Cao Y, Gao J, Yao F, Wu D, Mei H, Zhong Y, Ge Y, Xu H, Jiang W, Xiao X, Jiang Y, Hu S, Wu Y, Liu Y
Journal of hazardous materials 2024 Dec 5;480:135814
Journal of hazardous materials 2024 Dec 5;480:135814
Discovery of non-antiproliferative selective estrogen receptor degraders (SERDs) based on scaffold optimization of elacestrant.
Lu Y, Zhao Z, Wang S, Zheng T, Chen X, Liu L, Zhu Y, Liu W
European journal of medicinal chemistry 2024 Dec 5;279:116897
European journal of medicinal chemistry 2024 Dec 5;279:116897
Allosteric site identification, virtual screening and discovery of a sulfonamide Hsp110-STAT3 interaction inhibitor for the treatment of hypoxic pulmonary arterial hypertension.
Zhao C, Wu Y, Li M, Tan W, Hu Y, Wang Y, Gao R, Hu L, Li Q
European journal of medicinal chemistry 2024 Dec 5;279:116855
European journal of medicinal chemistry 2024 Dec 5;279:116855
SENP3-FIS1 axis promotes mitophagy and cell survival under hypoxia.
Zhao A, Maple L, Jiang J, Myers KN, Jones CG, Gagg H, McGarrity-Cottrell C, Rominiyi O, Collis SJ, Wells G, Rahman M, Danson SJ, Robinson D, Smythe C, Guo C
Cell death & disease 2024 Dec 5;15(12):881
Cell death & disease 2024 Dec 5;15(12):881
RG108 attenuates acute kidney injury by inhibiting P38 MAPK/FOS and JNK/JUN pathways.
Kong FX, Liu H, Xu T, Li SJ, Li W, Lu H, Ma NN, Wang YL, Shi JH, Yang YR, Wang FL
International immunopharmacology 2024 Dec 5;142(Pt A):113077
International immunopharmacology 2024 Dec 5;142(Pt A):113077
Evaluation of ALKBH2 and ALKBH3 gene regulation in patients with adult T-cell leukemia/lymphoma.
Wada Y, Naito T, Fukushima T, Saito M
Virology journal 2024 Dec 4;21(1):316
Virology journal 2024 Dec 4;21(1):316
Uric acid mediates kidney tubular inflammation through the LDHA/ROS/NLRP3 pathway.
Ouyang J, Wang H, Gan Y, Huang J
Clinical and experimental hypertension (New York, N.Y. : 1993) 2024 Dec 31;46(1):2424834
Clinical and experimental hypertension (New York, N.Y. : 1993) 2024 Dec 31;46(1):2424834
Epigenetic silencing ZSCAN23 promotes pancreatic cancer growth by activating Wnt signaling.
Du Q, Zhang M, Gao A, He T, Guo M
Cancer biology & therapy 2024 Dec 31;25(1):2302924
Cancer biology & therapy 2024 Dec 31;25(1):2302924
hnRNPLL regulates MYOF alternative splicing and correlates with early metastasis in pancreatic ductal adenocarcinoma.
Chen X, Gong R, Wang L, Lei K, Liu X, Wang J, Sun M, Saluja AK, Yu Q, Ren H
Cancer letters 2024 Dec 30;611:217436
Cancer letters 2024 Dec 30;611:217436
SLC15A2 Serves as a Novel Prognostic Biomarker and Target for Prostate Cancer.
Yin W, He P, Zou Z, Lin J, Liang Z, Wu Z, Ye J, Lu J, Zhong W
Anticancer research 2024 Dec 30;45(1):153-172
Anticancer research 2024 Dec 30;45(1):153-172
MicroRNA-668 alleviates renal fibrosis through PPARα/PGC-1α pathway.
Wang X, Gu Z, Huang Y, Wang J, Tang S, Yang X, Wang J
European journal of medical research 2024 Dec 28;29(1):631
European journal of medical research 2024 Dec 28;29(1):631
Identification and validation of up-regulated TNFAIP6 in osteoarthritis with type 2 diabetes mellitus.
Liu S, Chen H, Yang X, Wen Y, Chen L
Scientific reports 2024 Dec 28;14(1):31450
Scientific reports 2024 Dec 28;14(1):31450
Identification of a novel immune checkpoint-related gene signature predicts prognosis and immunotherapy in breast cancer and experiment verification.
Yin K, Guo Y, Wang J, Guo S, Zhang C, Dai Y, Guo Y, Dai C
Scientific reports 2024 Dec 28;14(1):31065
Scientific reports 2024 Dec 28;14(1):31065
Acetyl-11-keto-β-boswellia acid attenuates Ti particle-induced osteoblastic oxidative stress and osteolysis through the Foxo3 signaling pathway.
Gu Y, Wu Z, Xie H, Qian Z, Li Z, Tang Y, Wang Q, Fang T, Tao H, Chen K, Zhu P, Ding Y, Xu Y, Peng Y, Ye H, Guo X, Tao Y, Gu Y
International immunopharmacology 2024 Dec 25;143(Pt 3):113547
International immunopharmacology 2024 Dec 25;143(Pt 3):113547
Isoliquiritigenin alleviates neuropathic pain by reducing microglia inflammation through inhibition of the ERK signaling pathway and decreasing CEBPB transcription expression.
Wang Z, Jia S, Kang X, Chen S, Zhang L, Tian Z, Liang X, Meng C
International immunopharmacology 2024 Dec 25;143(Pt 3):113536
International immunopharmacology 2024 Dec 25;143(Pt 3):113536
SUCNR 1 promotes atherosclerosis by inducing endoplasmic reticulum stress mediated ER-mito crosstalk.
Yuan C, Yu B, Li L, Chen J, Qin W, Zhou Z, Su M, Wang D, Zhang Y, Wu Q, He C, Wei D
International immunopharmacology 2024 Dec 25;143(Pt 3):113510
International immunopharmacology 2024 Dec 25;143(Pt 3):113510
Ibuprofen modulates macrophage polarization by downregulating poly (ADP-ribose) polymerase 1.
Wang PH, Wang Y, Guo YY, Ma ZH, Wu C, Xing L
International immunopharmacology 2024 Dec 25;143(Pt 3):113502
International immunopharmacology 2024 Dec 25;143(Pt 3):113502
Micheliolide ameliorates severe acute pancreatitis in mice through potentiating Nrf2-mediated anti-inflammation and anti-oxidation effects.
Wu CY, Wang KQ, Qin YY, Wang HW, Wu MM, Zhu XD, Lu XY, Zhu MM, Lu CS, Hu QQ
International immunopharmacology 2024 Dec 25;143(Pt 2):113490
International immunopharmacology 2024 Dec 25;143(Pt 2):113490
-RAMP3 promotes hepatocellular carcinoma tumor cell-mediated CCL2 degradation by supporting membrane distribution of ACKR2.
Yang L, Fang A, Zhou S, Liu H
International immunopharmacology 2024 Dec 25;143(Pt 2):113419
International immunopharmacology 2024 Dec 25;143(Pt 2):113419
Asiaticoside protects against lung injury induced by intestinal ischemia/reperfusion via the upregulation of FoxM1.
Zheng M, Wang Y, Wang P, Tan X, Chen H, Zhang X, Zu G
International immunopharmacology 2024 Dec 25;143(Pt 2):113405
International immunopharmacology 2024 Dec 25;143(Pt 2):113405
N1-methyladenosine RNA methylation patterns are associated with an increased risk to biochemical recurrence in prostate cancer and serve as a potential novel biomarker for patient stratification.
Deng Y, Tan Z, Cai S, Feng Y, Tang Z, Li J, He H, Wu Z, Liu R, Huang H, Ye J, Han Z, Zhong W
International immunopharmacology 2024 Dec 25;143(Pt 2):113404
International immunopharmacology 2024 Dec 25;143(Pt 2):113404
Sulforaphane potentiates the efficacy of chemoradiotherapy in glioblastoma by selectively targeting thioredoxin reductase 1.
Ge Y, Ge Z, Tian F, Tai X, Chen D, Sun S, Shi Z, Yin J, Wei G, Li D, Wang L, Xu W, Tong M, Liu F, Zhao L, Qian X, Ge X
Cancer letters 2024 Dec 24;611:217429
Cancer letters 2024 Dec 24;611:217429
Macrophage-derived cathepsin L promotes epithelial-mesenchymal transition and M2 polarization in gastric cancer.
Xiao LX, Li XJ, Yu HY, Qiu RJ, Zhai ZY, Ding WF, Zhu MS, Zhong W, Fang CF, Yang J, Chen T, Yu J
World journal of gastroenterology 2024 Dec 21;30(47):5032-5054
World journal of gastroenterology 2024 Dec 21;30(47):5032-5054
SNRNP70 regulates the splicing of CD55 to promote osteosarcoma progression.
Li W, Wang L, Tian W, Ji W, Bing D, Wang Y, Xu B, Feng J, Zhang P, Liang H, Gu Y, Yang B
JCI insight 2024 Dec 20;9(24)
JCI insight 2024 Dec 20;9(24)
Nrf2/NRF1 signaling activation and crosstalk amplify mitochondrial biogenesis in the treatment of triptolide-induced cardiotoxicity using calycosin.
Qi XM, Zhang WZ, Zuo YQ, Qiao YB, Zhang YL, Ren JH, Li QS
Cell biology and toxicology 2024 Dec 20;41(1):2
Cell biology and toxicology 2024 Dec 20;41(1):2
ANGPTL4 mediated mesothelial-mesenchymal transition in pulmonary fibrosis: a potential therapeutic target.
Xia Y, Zhou F, Hui H, Dai L, Ouyang S
Journal of translational medicine 2024 Dec 20;22(1):1114
Journal of translational medicine 2024 Dec 20;22(1):1114
Inhibition of TFAM-Mediated Mitophagy by Oroxylin A Restored Sorafenib Sensitivity Under Hypoxia Conditions in HepG2 Cells.
Ji S, Xu X, Li Y, Sun S, Fu Q, Qiu Y, Wang S, Xia S, Wang F, Zhang F, Xuan J, Zheng S
Pharmaceuticals (Basel, Switzerland) 2024 Dec 20;17(12)
Pharmaceuticals (Basel, Switzerland) 2024 Dec 20;17(12)
Homoharringtonine promotes non-small-cell lung cancer cell death via modulating HIF-1α/ERβ/E2F1 feedforward loop.
Su Q, Ren J, Chen K, Leong SW, Han X, Li N, Wu J, Zhang Y
The Journal of pharmacy and pharmacology 2024 Dec 2;76(12):1647-1659
The Journal of pharmacy and pharmacology 2024 Dec 2;76(12):1647-1659
Comparison of biocompatibility of epoxy resin and bioceramic-based root canal sealers.
Uygun AD, Şen S, Çelik S
Clinical oral investigations 2024 Dec 2;28(12):673
Clinical oral investigations 2024 Dec 2;28(12):673
TRAIP enhances progression of tongue squamous cell carcinoma through EMT and Wnt/β-catenin signaling by interacting with DDX39A.
Liu L, Wang P, Guo C, Song L, Chen L, Qi H, Zheng Y, Xing X, Wang C
BMC cancer 2024 Dec 2;24(1):1481
BMC cancer 2024 Dec 2;24(1):1481
NCAM1 modulates the proliferation and migration of pulmonary arterial smooth muscle cells in pulmonary hypertension.
Chen Y, Liu N, Yang Y, Yang L, Li Y, Qiao Z, Zhang Y, Li A, Xiang R, Wen L, Huang W
Respiratory research 2024 Dec 19;25(1):435
Respiratory research 2024 Dec 19;25(1):435
17β-estradiol alleviated ferroptotic neuroinflammation by suppressing ATF4 in mouse model of Parkinson's disease.
Wang G, Zhuang W, Zhou Y, Wang X, Li Z, Liu C, Li W, He M, Lv E
Cell death discovery 2024 Dec 19;10(1):507
Cell death discovery 2024 Dec 19;10(1):507
Integrated network pharmacology and transcriptomics to explore the mechanism of compound Dihuang granule (CDG) protects dopaminergic neurons by regulating the Nrf2/HMOX1 pathway in the 6-OHDA/MPP(+)-induced model of Parkinson's disease.
Sun X, Yang S, He Z, Wang L, He J
Chinese medicine 2024 Dec 18;19(1):170
Chinese medicine 2024 Dec 18;19(1):170
IGF2BP2 promotes lung adenocarcinoma progression by regulating LOX1 and tumor-associated neutrophils.
Qian L, Ji Z, Mei L, Zhao J
Immunologic research 2024 Dec 17;73(1):16
Immunologic research 2024 Dec 17;73(1):16
Role of AhR-Hsp90-MDM2-mediated VDR ubiquitination in PM2.5-induced renal toxicity.
Zhang P, Wang L, Zhang J, An Q, Wang Y, Hu N, Pu D, He L, Huang J
Environmental research 2024 Dec 15;263(Pt 2):120174
Environmental research 2024 Dec 15;263(Pt 2):120174
Chronic microcystin-leucine-arginine exposure induces osteoporosis by breaking the balance of osteoblasts and osteoclasts.
Pan C, Wang K, Hong R, Wang X, Zhang Y, Fan Z, Shi Y, Liu T, Chen H
Environmental research 2024 Dec 15;263(Pt 2):120098
Environmental research 2024 Dec 15;263(Pt 2):120098
Matrine promotes colorectal cancer apoptosis by downregulating shank-associated RH domain interactor expression.
Zhou YC, Wang QQ, Zhou GY, Yin TF, Zhao DY, Sun XZ, Tan C, Zhou L, Yao SK
World journal of gastrointestinal oncology 2024 Dec 15;16(12):4700-4715
World journal of gastrointestinal oncology 2024 Dec 15;16(12):4700-4715
GS-4997 halts the progression of tubulointerstitial injury in lupus nephritis.
Xiao Z, Li G, Fu S, Chen Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Dec 13;38(24):e70253
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Dec 13;38(24):e70253
Overexpression of miR-133a-3p reduces microglia activation by binding to GCH1, alleviating neuroinflammation and neuropathic pain.
Gao C, Yang T, Shu J, Gao X, Meng C
Experimental brain research 2024 Dec 12;243(1):23
Experimental brain research 2024 Dec 12;243(1):23
Endosome maturation is orchestrated by inside-out proton signaling through a Na+/H+ exchanger and pH-dependent Rab GTPase cycling.
Lee Y, Ouyang Q, Riaz HA, Ma L, Fleishman M, Schmidt M, Dupree JL, Lambright DG, Morrow EM
bioRxiv : the preprint server for biology 2024 Dec 12;
bioRxiv : the preprint server for biology 2024 Dec 12;
Mycoplasma synoviae Induces Apoptosis in Chicken Oviduct Cells.
Zhang X, Wu X, Zhang Y, Chen Y, Li T, Shi Y, Bao S
Veterinary sciences 2024 Dec 10;11(12)
Veterinary sciences 2024 Dec 10;11(12)
TRIM24-DTNBP1-ATP7A mediated astrocyte cuproptosis in cognition and memory dysfunction caused by Y(2)O(3) NPs.
Chen Z, Liu J, Zheng M, Mo M, Hu X, Liu C, Pathak JL, Wang L, Chen L
The Science of the total environment 2024 Dec 1;954:176353
The Science of the total environment 2024 Dec 1;954:176353
Ion channel Piezo1 induces ferroptosis of trabecular meshwork cells: a novel observation in the pathogenesis in primary open angle glaucoma.
Liu K, Xu J, Yang R, Wang F, Su Y
American journal of physiology. Cell physiology 2024 Dec 1;327(6):C1591-C1603
American journal of physiology. Cell physiology 2024 Dec 1;327(6):C1591-C1603
Integrated Analysis of Single-Cell and Bulk RNA Sequencing Reveals HSD3B7 as a Prognostic Biomarker and Potential Therapeutic Target in ccRCC.
Liu G, Liu Q, Zhao J, Luo R, Wan Y, Luo Z
International journal of molecular sciences 2024 Dec 1;25(23)
International journal of molecular sciences 2024 Dec 1;25(23)
TRPM7 contributes to pyroptosis and its involvement in status epilepticus.
Tong X, Tong Y, Zheng J, Shi R, Liang H, Li M, Meng Y, Shi J, Zhao D, Seehus CR, Wang J, Xu X, Boczek T, Suzuki S, Fleig A, Penner R, Zhang N, Xu J, Duan J, Yu Z, Wang W, Zhao W, Guo F
Journal of neuroinflammation 2024 Dec 1;21(1):315
Journal of neuroinflammation 2024 Dec 1;21(1):315
O-GlcNAc participates in the meiosis of aging oocytes by mediating mitochondrial function.
Li C, Qian Z, Zhang H, Ge X, Chen L, Xue M, Tang T, He Z, Zheng L, Cao C, Zhang K, Ma R, Yao B
Reproduction (Cambridge, England) 2024 Dec 1;168(6)
Reproduction (Cambridge, England) 2024 Dec 1;168(6)
Enhancing therapeutic efficacy in homologous recombination-proficient pancreatic cancer via the combination of PARP1-PROTAC and a BRD4 inhibitor.
Pu C, Liu Y, Lan S, Fan H, Liu L, Liu J, Guo Y
Bioorganic & medicinal chemistry 2024 Dec 1;115:117970
Bioorganic & medicinal chemistry 2024 Dec 1;115:117970
Zishen Qingre Lishi Huayu Recipe May Ameliorate the Symptoms of PCOS Model Rats via Alleviating Systemic and Ovarian Inflammation.
Li X, Yi Y, Ren Y, Zhang Y, Wang CC, Liu C, Liu S, Zhan X, Yu X, Liang R
American journal of reproductive immunology (New York, N.Y. : 1989) 2024 Aug;92(2):e13918
American journal of reproductive immunology (New York, N.Y. : 1989) 2024 Aug;92(2):e13918
Sweroside alleviates pressure overload-induced heart failure through targeting CaMKⅡδ to inhibit ROS-mediated NF-κB/NLRP3 in cardiomyocytes.
Wang D, Yu X, Gao K, Li F, Li X, Pu H, Zhang P, Guo S, Wang W
Redox biology 2024 Aug;74:103223
Redox biology 2024 Aug;74:103223
Cellular Retinoic Acid Binding Protein 2 (CRABP2), Up-regulated by HPV E6/E7, Leads to Aberrant Activation of the Integrin β1/FAK/ERK Signaling Pathway and Aggravates the Malignant Phenotypes of Cervical Cancer.
Liu J, Tang L, Chu W, Wei L
Biochemical genetics 2024 Aug;62(4):2686-2701
Biochemical genetics 2024 Aug;62(4):2686-2701
Anti-adipogenesis effect of indole-3-acrylic acid on human preadipocytes and HFD-induced zebrafish.
Zhang L, Zhao J, Peng Z, Zhang Z, Huang S, Dong X, Gao J, Guo X
Acta diabetologica 2024 Aug;61(8):975-985
Acta diabetologica 2024 Aug;61(8):975-985
Methylene Blue Pretreatment Protects Against Repeated Neonatal Isoflurane Exposure-Induced Brain Injury and Memory Loss.
Wu C, Deng Q, Zhu L, Liu TC, Duan R, Yang L
Molecular neurobiology 2024 Aug;61(8):5787-5801
Molecular neurobiology 2024 Aug;61(8):5787-5801
CCL2 Potentiates Inflammation Pain and Related Anxiety-Like Behavior Through NMDA Signaling in Anterior Cingulate Cortex.
Guo H, Hu WC, Xian H, Shi YX, Liu YY, Ma SB, Pan KQ, Wu SX, Xu LY, Luo C, Xie RG
Molecular neurobiology 2024 Aug;61(8):4976-4991
Molecular neurobiology 2024 Aug;61(8):4976-4991
Capsaicin attenuates Porphyromonas gingivalis-suppressed osteogenesis of periodontal ligament stem cells via regulating mitochondrial function and activating PI3K/AKT/mTOR pathway.
Wang W, Zhou Z, Ding T, Feng S, Liu H, Liu M, Ge S
Journal of periodontal research 2024 Aug;59(4):798-811
Journal of periodontal research 2024 Aug;59(4):798-811
SNX14 inhibits autophagy via the PI3K/AKT/mTOR signaling cascade in breast cancer cells.
Lv S, Jiang H, Yu L, Zhang Y, Sun L, Xu J
Journal of molecular histology 2024 Aug;55(4):391-401
Journal of molecular histology 2024 Aug;55(4):391-401
Toxicity mechanism of acrolein on energy metabolism disorder and apoptosis in human ovarian granulosa cells.
Liu X, Li R, Xiu Z, Tang S, Duan Y
Toxicology 2024 Aug;506:153861
Toxicology 2024 Aug;506:153861
GOLPH3 inhibits erastin-induced ferroptosis in colorectal cancer cells.
Chen L, Wang C, Chen X, Wu Y, Chen M, Deng X, Qiu C
Cell biology international 2024 Aug;48(8):1198-1211
Cell biology international 2024 Aug;48(8):1198-1211
The salt sensitivity of Drd4-null mice is associated with the upregulations of sodium transporters in kidneys.
Zhang M, Liu M, Wang W, Ren Z, Wang P, Xue Y, Wang X
Hypertension research : official journal of the Japanese Society of Hypertension 2024 Aug;47(8):2144-2156
Hypertension research : official journal of the Japanese Society of Hypertension 2024 Aug;47(8):2144-2156
Effect of Jiedu Huayu decoction on oral mucosal Axin and β-catenin expression in oral submucosal fibrosis model rats.
Xuan Z, An L, Keke Z, Mingyu R
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2024 Aug;44(4):688-693
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2024 Aug;44(4):688-693
Ezetimibe ketone protects against renal ischemia-reperfusion injury and attenuates oxidative stress via activation of the Nrf2/HO-1 signaling pathway.
Chen Z, Wang K, He X, Xue D, Ma X
Journal of biochemical and molecular toxicology 2024 Aug;38(8):e23792
Journal of biochemical and molecular toxicology 2024 Aug;38(8):e23792
Exosomal miR-130b-3p suppresses metastasis of non-small cell lung cancer cells by targeting DEPDC1 via TGF-β signaling pathway.
Lv M, Li X, Zheng C, Tian W, Yang H, Yin Z, Zhou B
International journal of biological macromolecules 2024 Aug;275(Pt 1):133594
International journal of biological macromolecules 2024 Aug;275(Pt 1):133594
A gelatin methacryloyl (GelMA) treated with gallic acid and coated with specially designed nanoparticles derived from ginseng enhances the healing of wounds in diabetic rats.
Yu YL, Zheng JC, Duan P, Cheng YN, Zhang H, Zheng L, Yu ZR, Xu JM, Hu HX, Pan ZY
International journal of biological macromolecules 2024 Aug;274(Pt 1):133372
International journal of biological macromolecules 2024 Aug;274(Pt 1):133372
EYA4 reduces chemosensitivity of osteosarcoma to doxorubicin through DNA damage repair.
Heng W, Wang T, Wei F, Yang F, Chen C, Yu Z, Du M, Qian J, Zhou C
Biochemical pharmacology 2024 Aug;226:116366
Biochemical pharmacology 2024 Aug;226:116366
The Role of Histone H2B Acetylation Modification in Aluminum-Induced Cognitive Dysfunction.
Gao J, Liu W, Pei J, Li J, Hao N, Yang S, Yang X, Zou D, Xu K, Zhang L
Biological trace element research 2024 Aug;202(8):3731-3739
Biological trace element research 2024 Aug;202(8):3731-3739
Celastrol alleviates subconjunctival fibrosis induced by silicone implants mimicking glaucoma surgery.
Wang Y, Geng X, Sun X, Cui H, Guo Z, Chu D, Li J, Li Z
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2024 Aug;201:114352
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2024 Aug;201:114352
NAMPT Overexpression Drives Cell Growth in Polycystic Liver Disease through Mitochondrial Metabolism Regulation.
Pant K, Gradilone SA
The American journal of pathology 2024 Aug;194(8):1528-1537
The American journal of pathology 2024 Aug;194(8):1528-1537
Changes in PI3K/AKT and NRF2/HO-1 signaling expression and intestinal microbiota in bleomycin-induced pulmonary fibrosis.
Li C, Cao Y, Peng Y, Ma T, Wu F, Hua Y, Wang X, Bai T, Wei Y, Ji P
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Aug;190:114796
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Aug;190:114796
PGC-1α/LDHA signaling facilitates glycolysis initiation to regulate mechanically induced bone remodeling under inflammatory microenvironment.
Liu J, Wang J, Wang Z, Ren H, Zhang Z, Fu Y, Li L, Shen Z, Li T, Tang S, Wei F
Bone 2024 Aug;185:117132
Bone 2024 Aug;185:117132
Novel meroterpene-like compounds inhibit ferroptosis through Fe(2+) chelation.
Lou S, Liu YX, Xia C, Zhang Q, Deng L, Tang JJ
The international journal of biochemistry & cell biology 2024 Aug;173:106610
The international journal of biochemistry & cell biology 2024 Aug;173:106610
Gain-of-function variants in GSDME cause pyroptosis and apoptosis associated with post-lingual hearing loss.
Xiao Y, Chen L, Xu K, Zhou M, Han Y, Luo J, Ai Y, Wang M, Jin Y, Qiao R, Kong S, Fan Z, Xu L, Wang H
Human genetics 2024 Aug;143(8):979-993
Human genetics 2024 Aug;143(8):979-993
Pharmacological control of angiogenesis by regulating phosphorylation of myosin light chain 2.
Tsuji-Tamura K, Sato M, Tamura M
Cellular signalling 2024 Aug;120:111223
Cellular signalling 2024 Aug;120:111223
Degrasyn alleviates osteoarthritis by blocking macrophagic pyroptosis via suppressing NLRP3/GSDMD signaling pathway and protecting chondrocytes.
Xie S, Wang L, Lu C, Chen H, Ding Y, Jian X, Zhang Z, Zhu L
Cellular signalling 2024 Aug;120:111220
Cellular signalling 2024 Aug;120:111220
Extracellular vesicles derived from stored red blood cell suspensions enhance invasion and migration of lung cancer cells by miR1246 and miR150-3p.
Cheng Z, Kong Y, Xu H, Xiao L, Tian L, Liu Z
Vox sanguinis 2024 Aug;119(8):809-820
Vox sanguinis 2024 Aug;119(8):809-820
CKB Promotes Mitochondrial ATP Production by Suppressing Permeability Transition Pore.
He L, Lin J, Lu S, Li H, Chen J, Wu X, Yan Q, Liu H, Li H, Shi Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(31):e2403093
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(31):e2403093
Inhibitory effects of Belamcanda extract on inflammatory response and antiviral mechanism in H9N2 Avian influenza virus: insights from in vitro and in vivo studies.
Zhi Y, Wei J, Liu Z, Zhang Q, Zhang T, Hu G
Poultry science 2024 Aug;103(8):103885
Poultry science 2024 Aug;103(8):103885
CircHIPK3/miR-124 affects angiogenesis in early-onset preeclampsia via CPT1A-mediated fatty acid oxidation.
Wu Y, Huang J, Liu L, Zhang X, Zhang W, Li Q
Journal of molecular medicine (Berlin, Germany) 2024 Aug;102(8):1037-1049
Journal of molecular medicine (Berlin, Germany) 2024 Aug;102(8):1037-1049
A metabolic reprogramming-related gene signature correlates with prognosis and proliferation of BLCA.
Wu Y, Luo Y, Li T
Discover oncology 2024 Aug 8;15(1):338
Discover oncology 2024 Aug 8;15(1):338
PDIA3 orchestrates effector T cell program by serving as a chaperone to facilitate the non-canonical nuclear import of STAT1 and PKM2.
Yang CL, Wang FX, Luo JH, Rong SJ, Lu WY, Chen QJ, Xiao J, Wang T, Song DN, Liu J, Mo Q, Li S, Chen Y, Wang YN, Liu YJ, Yan T, Gu WK, Zhang S, Xiong F, Yu QL, Zhang ZY, Yang P, Liu SW, Eizirik D, Dong LL, Sun F, Wang CY
Molecular therapy : the journal of the American Society of Gene Therapy 2024 Aug 7;32(8):2778-2797
Molecular therapy : the journal of the American Society of Gene Therapy 2024 Aug 7;32(8):2778-2797
GelMA loaded with platelet lysate promotes skin regeneration and angiogenesis in pressure ulcers by activating STAT3.
Jin T, Fu Z, Zhou L, Chen L, Wang J, Wang L, Yan S, Li T, Jin P
Scientific reports 2024 Aug 7;14(1):18345
Scientific reports 2024 Aug 7;14(1):18345
Vasorin (VASN) overexpression promotes pulmonary metastasis and resistance to adjuvant chemotherapy in patients with locally advanced rectal cancer.
Kang D, Huang S, Liao Y, Mi S, Zhou J, Feng Y, Huang R, Lu ZH, Pan ZZ, Ma W, Chen G, Yue JX, Huang J, Zhang RX
Journal of translational medicine 2024 Aug 6;22(1):742
Journal of translational medicine 2024 Aug 6;22(1):742
Identification of ferroptosis-related key genes associated with immune infiltration in sepsis by bioinformatics analysis and in vivo validation.
Shi R, Bai C, Sun S, Wang F, Li C, Wang C, Hu L, Zhao Z, Guo Q, Du G, Xu D, Chen AF, Yang W
Gene 2024 Aug 5;918:148482
Gene 2024 Aug 5;918:148482
Inhibition of TFEB deacetylation in proximal tubular epithelial cells (TECs) promotes TFEB activation and alleviates TEC damage in diabetic kidney disease.
Li X, Zhang Y, Chen H, Wu Y, Chen Y, Gong S, Liu Y, Liu H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Aug 31;38(16):e23884
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Aug 31;38(16):e23884
Bergenin protects against osteoarthritis by inhibiting STAT3, NF-κB and Jun pathways and suppressing osteoclastogenesis.
Zhang Z, Li B, Wu S, Yang Y, Wu B, Lai Q, Lai F, Mo F, Zhong Y, Wang S, Guo R, Zhang B
Scientific reports 2024 Aug 31;14(1):20292
Scientific reports 2024 Aug 31;14(1):20292
Inhibition of cGAS attenuates neonatal hypoxic-ischemic encephalopathy via regulating microglia polarization and pyroptosis.
Shen H, Lu H, Mao L, Song L
Translational pediatrics 2024 Aug 31;13(8):1378-1394
Translational pediatrics 2024 Aug 31;13(8):1378-1394
Bacillus subtilis alleviates excessive apoptosis of intestinal epithelial cells in intrauterine growth restriction suckling piglets via the members of Bcl-2 and caspase families.
Xie Z, Yun Y, Yu G, Zhang X, Zhang H, Wang T, Zhang L
Journal of the science of food and agriculture 2024 Aug 30;104(11):6924-6932
Journal of the science of food and agriculture 2024 Aug 30;104(11):6924-6932
Combined bacterial translocation and cholestasis aggravates liver injury by activation pyroptosis in obstructive jaundice.
Shen X, Zhang X, Li K, Huang G, Li X, Hou Y, Ge X
Heliyon 2024 Aug 30;10(16):e35793
Heliyon 2024 Aug 30;10(16):e35793
Indole-3-aldehyde Alleviates High-Fat Diet-Induced Gut Barrier Disruption by Increasing Intestinal Stem Cell Expansion.
Zhang J, Zhang R, Chen Y, Guo X, Ren Y, Wang M, Li X, Huang Z, Zhu W, Yu K
Journal of agricultural and food chemistry 2024 Aug 28;72(34):18930-18941
Journal of agricultural and food chemistry 2024 Aug 28;72(34):18930-18941
Pterostilbene improves neurological dysfunction and neuroinflammation after ischaemic stroke via HDAC3/Nrf1-mediated microglial activation.
Chen Y, He W, Qiu J, Luo Y, Jiang C, Zhao F, Wei H, Meng J, Long T, Zhang X, Yang L, Xu Q, Wang J, Zhang C
Cellular & molecular biology letters 2024 Aug 28;29(1):114
Cellular & molecular biology letters 2024 Aug 28;29(1):114
Regulatory effect of β-glucan secreted by Rhizobium pusense on triglyceride metabolism and their relationships with the modulation of intestinal microbiota in mice fed a high-fat diet.
Zhang B, Zhao W, Song D, Lyu X
Food & function 2024 Aug 27;15(17):8759-8774
Food & function 2024 Aug 27;15(17):8759-8774
NLRP4 renders pancreatic cancer resistant to olaparib through promotion of the DNA damage response and ROS-induced autophagy.
Xiao M, Yang J, Dong M, Mao X, Pan H, Lei Y, Tong X, Yu X, Yu X, Shi S
Cell death & disease 2024 Aug 26;15(8):620
Cell death & disease 2024 Aug 26;15(8):620
circNDUFA13 stimulates adipogenesis of bone marrow-derived mesenchymal stem cells via interaction with STAT3.
Huang L, He S, Wang T, Long K, Ma B, Wu P, Gong Y, Zhong D, Yang Q, Wu J, Li X
Scientific reports 2024 Aug 26;14(1):19787
Scientific reports 2024 Aug 26;14(1):19787
Tert promotes cardiac regenerative repair after MI through alleviating ROS-induced DNA damage response in cardiomyocyte.
Wei X, Zhou Y, Shao E, Shi X, Han Y, Zhang Y, Wei G, Zheng H, Huang S, Chen Y, Sun J, Liao Y, Liao W, Wang Y, Bin J, Li X
Cell death discovery 2024 Aug 26;10(1):381
Cell death discovery 2024 Aug 26;10(1):381
MYH6 suppresses tumor progression by downregulating KIT expression in human prostate cancer.
Wang F, Shen H, Li K, Ding Y, Wang J, Sun J
Scientific reports 2024 Aug 24;14(1):19685
Scientific reports 2024 Aug 24;14(1):19685
Biallelic variants in DAP3 result in reduced assembly of the mitoribosomal small subunit with altered intrinsic and extrinsic apoptosis and a Perrault syndrome-spectrum phenotype.
Smith TB, Kopajtich R, Demain LAM, Rea A, Thomas HB, Schiff M, Beetz C, Joss S, Conway GS, Shukla A, Yeole M, Radhakrishnan P, Azzouz H, Ben Chehida A, Elmaleh-Bergès M, Glasgow RIC, Thompson K, Oláhová M, He L, Jenkinson EM, Jahic A, Belyantseva IA, Barzik M, Urquhart JE, O' Sullivan J, Williams SG, Bhaskar SS, Carrera S, Blakes AJM, Banka S, Yue WW, Ellingford JM, Houlden H, DDD Study, Munro KJ, Friedman TB, Taylor RW, Prokisch H, O'Keefe RT, Newman WG
medRxiv : the preprint server for health sciences 2024 Aug 21;
medRxiv : the preprint server for health sciences 2024 Aug 21;
ISIR and its human homolog gene AK131315 strengthen LPS-induced inflammation and acute lung injury by promoting TAK1-dependent NF-κB and MAPK signaling.
Sun T, Wang F, Li J, Wei W, Wang Y, Tong Z, Zou W
International immunopharmacology 2024 Aug 20;137:112510
International immunopharmacology 2024 Aug 20;137:112510
MiR-625-5p is a potential therapeutic target in sepsis by regulating CXCL16/CXCR6 axis and endothelial barrier.
Huang X, Fei Y, Qiu X, Qian T, Shang Q, Cui J, Song Y, Sheng S, Xiao W, Yu Q, Wang T, Wang X
International immunopharmacology 2024 Aug 20;137:112508
International immunopharmacology 2024 Aug 20;137:112508
Toll-like receptor 4 deficiency affects the balance of osteoclastogenesis and osteoblastogenesis in periodontitis.
Pan L, She H, Hu Y, Liu L, Wang H, Zhu L
International immunopharmacology 2024 Aug 20;137:112500
International immunopharmacology 2024 Aug 20;137:112500
Wedelolactone suppresses breast cancer growth and metastasis via regulating TGF-β1/Smad signaling pathway.
Li H, Hou M, Zhang P, Ren L, Guo Y, Zou L, Cao J, Bai Z
The Journal of pharmacy and pharmacology 2024 Aug 2;76(8):1038-1050
The Journal of pharmacy and pharmacology 2024 Aug 2;76(8):1038-1050
Taurine Alleviates Ferroptosis-Induced Metabolic Impairments in C2C12 Myoblasts by Stabilizing the Labile Iron Pool and Improving Redox Homeostasis.
Liu X, Zhou Y, Qi Z, Huang C, Lin D
Journal of proteome research 2024 Aug 2;23(8):3444-3459
Journal of proteome research 2024 Aug 2;23(8):3444-3459
miR-450a-2-3p targets ERK(1/2) to ameliorate ISO-induced cardiac fibrosis in mice.
Liu L, Luo F
Genes & nutrition 2024 Aug 19;19(1):16
Genes & nutrition 2024 Aug 19;19(1):16
Inhibiting PRMT1 protects against CoNV by regulating macrophages through the FGF2/PI3K/Akt pathway.
Gao Y, Mao J, Zhang R, Deng Q, Wang Y, Pan Y, Liudi S, Wang Y, Fan X, Yang Y, Wan S
European journal of pharmacology 2024 Aug 15;977:176673
European journal of pharmacology 2024 Aug 15;977:176673
Potential mechanisms of aortic medial degeneration promoted by co-exposure to microplastics and lead.
Xie X, Wang K, Shen X, Li X, Wang S, Yuan S, Li B, Wang Z
Journal of hazardous materials 2024 Aug 15;475:134854
Journal of hazardous materials 2024 Aug 15;475:134854
The antihypertensive effect of Alizarin is achieved by activating VEGFR2/eNOS pathway, attenuating oxidative stress-induced mitochondrial damage and premature senescence.
Qian YW, Guo YQ, Li YL, Wang Y, Guo S, Niu QQ, Zhu ML, Li P
Life sciences 2024 Aug 15;351:122862
Life sciences 2024 Aug 15;351:122862
Atorvastatin improved ulcerative colitis in association with gut microbiota-derived tryptophan metabolism.
Gou Y, Cai S, Chen Y, Hou X, Zhang J, Bi C, Gu P, Yang M, Zhang H, Zhong W, Yuan H
Life sciences 2024 Aug 15;351:122790
Life sciences 2024 Aug 15;351:122790
Dietary rutin improves the antidiarrheal capacity of weaned piglets by improving intestinal barrier function, antioxidant capacity and cecal microbiota composition.
Ma L, Zhou B, Liu H, Chen S, Zhang J, Wang T, Wang C
Journal of the science of food and agriculture 2024 Aug 15;104(10):6262-6275
Journal of the science of food and agriculture 2024 Aug 15;104(10):6262-6275
MicroRNA-486-3p affects cisplatin resistance in high-grade serous ovarian cancer by regulating TMIGD2: An experimental study.
Wang J, Wu Y
Heliyon 2024 Aug 15;10(15):e34978
Heliyon 2024 Aug 15;10(15):e34978
Zhiqiao Gancao decoction regulated JAK2/STAT3/ macrophage M1 polarization to ameliorate intervertebral disc degeneration.
Huang Z, Shen X, Chen H, Zhu Z, Lu B, Zhang L, Liu Y, Li Y, Xu B
Heliyon 2024 Aug 15;10(15):e34715
Heliyon 2024 Aug 15;10(15):e34715
Butyrate promotes visceral hypersensitivity in IBS model via mast cell-derived DRG neuron lincRNA-01028-PKC-TRPV1 pathway.
Li Y-J, Li J, Dai C
mBio 2024 Aug 14;15(8):e0153324
mBio 2024 Aug 14;15(8):e0153324
Lys-63-specific deubiquitinase BRCC36 enhances the sensitivity of multiple myeloma cells to lenalidomide by inhibiting lysosomal degradation of cereblon.
Wang B, Li M, Cao D, Sun Q, Yu W, Ma J, Ren H, Xu G, Zhou L
Cellular and molecular life sciences : CMLS 2024 Aug 13;81(1):349
Cellular and molecular life sciences : CMLS 2024 Aug 13;81(1):349
Halting multiple myeloma with MALT1 inhibition: suppressing BCMA-induced NF-κB and inducing immunogenic cell death.
Yao Y, Yuan M, Shi M, Li W, Sha Y, Zhang Y, Yuan C, Luo J, Li Z, Liao C, Xu K, Niu M
Blood advances 2024 Aug 13;8(15):4003-4016
Blood advances 2024 Aug 13;8(15):4003-4016
Mitochondrial dysfunction in kidney stones and relief of kidney stones after reducing mtROS.
Xu Y, Li G, Ge D, Chen Y, Hou B, Hao Z
Urolithiasis 2024 Aug 13;52(1):117
Urolithiasis 2024 Aug 13;52(1):117
Orai1 and Orai3 act through distinct signalling axes to promote stemness and tumorigenicity of breast cancer stem cells.
Zhuo D, Lei Z, Dong L, Chan AML, Lin J, Jiang L, Qiu B, Jiang X, Tan Y, Yao X
Stem cell research & therapy 2024 Aug 13;15(1):256
Stem cell research & therapy 2024 Aug 13;15(1):256
Effects of Ginsenoside Rb1 on the Crosstalk between Intestinal Stem Cells and Microbiota in a Simulated Weightlessness Mouse Model.
Zong B, Wang J, Wang K, Hao J, Han JY, Jin R, Ge Q
International journal of molecular sciences 2024 Aug 12;25(16)
International journal of molecular sciences 2024 Aug 12;25(16)
Comprehensive analysis identifies ubiquitin ligase FBXO42 as a tumor-promoting factor in neuroblastoma.
Zhou J, Li Q, Deng X, Peng L, Sun J, Zhang Y, Du Y
Scientific reports 2024 Aug 12;14(1):18697
Scientific reports 2024 Aug 12;14(1):18697
Exploration of the underlying mechanism of Astragaloside III in attenuating immunosuppression via network pharmacology and vitro/vivo pharmacological validation.
He Y, Amer HM, Xu Z, Liu L, Wu S, He B, Liu J, Kai G
Journal of ethnopharmacology 2024 Aug 10;330:118235
Journal of ethnopharmacology 2024 Aug 10;330:118235
A novel PDGFR inhibitor WQ-C-401 prevents pulmonary vascular remodeling in rats with monocrotaline-induced pulmonary arterial hypertension.
Huang W, Zhou H, He Y, Wang A, Wang B, Chen Y, Liu C, Wang H, Xie W, Kong H
Experimental cell research 2024 Aug 1;441(1):114154
Experimental cell research 2024 Aug 1;441(1):114154
Asprosin contributes to vascular remodeling in hypertensive rats via superoxide signaling.
Xu ZQ, Li XZ, Zhu R, Ge R, Wei H, Shi HW, Wang Z, Yang C, Yang YW, Lu XJ, Chen AD, Zhu GQ, Tan X
Journal of hypertension 2024 Aug 1;42(8):1427-1439
Journal of hypertension 2024 Aug 1;42(8):1427-1439
Gut dysbiosis contributes to SCFAs reduction-associated adipose tissue macrophage polarization in gestational diabetes mellitus.
Li H, Liu S, Chen H, Zhou L, Chen B, Wang M, Zhang D, Han TL, Zhang H
Life sciences 2024 Aug 1;350:122744
Life sciences 2024 Aug 1;350:122744
PARP1 inhibition prevents oxidative stress in age-related hearing loss via PAR-Ca(2+)-AIF axis in cochlear strial marginal cells.
Wan H, Chen H, Liu J, Yang B, Zhang Y, Bai Y, Chen X, Wang J, Liu T, Zhang Y, Hua Q
Free radical biology & medicine 2024 Aug 1;220:222-235
Free radical biology & medicine 2024 Aug 1;220:222-235
Atorvastatin combined with imipenem alleviates lung injury in sepsis by inhibiting neutrophil extracellular trap formation via the ERK/NOX2 signaling pathway.
Zhang Y, Wu D, Sun Q, Luo Z, Zhang Y, Wang B, Chen W
Free radical biology & medicine 2024 Aug 1;220:179-191
Free radical biology & medicine 2024 Aug 1;220:179-191
HSK3486 Inhibits Colorectal Cancer Growth by Promoting Oxidative Stress and ATPase Inhibitory Factor 1 Activation.
Nan K, Zhong Z, Yue Y, Zhou W, Sun X, Shen Y, Qu M, Chen Z, Gu J, Sun C, Sun X, Lu L, Zhang J, Miao C, Sun M
Digestive diseases and sciences 2024 Apr;69(4):1214-1227
Digestive diseases and sciences 2024 Apr;69(4):1214-1227
Disturbance of mitochondrial dynamics in myocardium of broilers with pulmonary hypertension syndrome.
Zhang W, Li M, Ye X, Jiang M, Wu X, Tang Z, Hu L, Zhang H, Li Y, Pan J
British poultry science 2024 Apr;65(2):154-164
British poultry science 2024 Apr;65(2):154-164
Toll-like receptor 3 signaling drives enteric glial cells against dextran sulfate sodium-induced colitis in mice.
Zeng J, Lu QQ, Du XL, Yuan L, Yang XJ
Journal of molecular histology 2024 Apr;55(2):201-210
Journal of molecular histology 2024 Apr;55(2):201-210
Botulinum Toxin Type A Alleviates Androgenetic Alopecia by Inhibiting Apoptosis of Dermal Papilla Cells via Targeting circ_0135062/miR-506-3p/Bax Axis.
Wei W, Zhao G, Li Q, Zhang J, Wei H, Shen C, Zhao B, Ji Z, Wang L, Guo Y, Jin P
Aesthetic plastic surgery 2024 Apr;48(7):1473-1486
Aesthetic plastic surgery 2024 Apr;48(7):1473-1486
A novel 2-iminobenzimidazole compound, XYA1353, displays in vitro and in vivo anti-myeloma activity via targeting NF-κB signaling.
Gao J, Zhou J, Zhang M, Zhang Y, Zeng Y, Li S, Xu K, Yao R
Molecular and cellular biochemistry 2024 Apr;479(4):843-857
Molecular and cellular biochemistry 2024 Apr;479(4):843-857
Emodin suppresses alkali burn-induced corneal inflammation and neovascularization by the vascular endothelial growth factor receptor 2 signaling pathway.
Xueying Z, Liang G, Siyi L, Fengyue LI, Mingli L, Wanting L, Chun M, Guanghui L
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2024 Apr;44(2):268-276
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2024 Apr;44(2):268-276
Inflammatory Factor IL1α Induces Aberrant Astrocyte Proliferation in Spinal Cord Injury Through the Grin2c/Ca(2+)/CaMK2b Pathway.
Xia Y, Ding L, Zhang C, Xu Q, Shi M, Gao T, Zhou FQ, Deng DYB
Neuroscience bulletin 2024 Apr;40(4):421-438
Neuroscience bulletin 2024 Apr;40(4):421-438
Blood RNA-sequencing analysis in acrylamide-induced neurotoxicity and depressive symptoms in rats.
Chen YT, Lin TJ, Hung CY
Environmental toxicology 2024 Apr;39(4):2316-2325
Environmental toxicology 2024 Apr;39(4):2316-2325
Manganese induces oxidative damage in the hippocampus by regulating the expression of oxidative stress-related genes via modulation of H3K18 acetylation.
Chen Z, Ao C, Liu Y, Yang Y, Liu Y, Ming Q, Li C, Zhao H, Ban J, Li J
Environmental toxicology 2024 Apr;39(4):2240-2253
Environmental toxicology 2024 Apr;39(4):2240-2253
Identification of fangchinoline as a broad-spectrum enterovirus inhibitor through reporter virus based high-content screening.
Zhang QY, Li JQ, Li Q, Zhang Y, Zhang ZR, Li XD, Zhang HQ, Deng CL, Yang FX, Xu Y, Zhang B
Virologica Sinica 2024 Apr;39(2):301-308
Virologica Sinica 2024 Apr;39(2):301-308
Pimpinellin ameliorates macrophage inflammation by promoting RNF146-mediated PARP1 ubiquitination.
Yang L, Du M, Liu K, Wang P, Zhu J, Li F, Wang Z, Huang K, Liang M
Phytotherapy research : PTR 2024 Apr;38(4):1783-1798
Phytotherapy research : PTR 2024 Apr;38(4):1783-1798
Berberine ameliorates contrast-induced acute kidney injury by regulating HDAC4-FoxO3a axis-induced autophagy: In vivo and in vitro.
Zuo Z, Li Q, Zhou S, Yu R, Wu C, Chen J, Xiao Y, Chen H, Song J, Pan Y, Wang W
Phytotherapy research : PTR 2024 Apr;38(4):1761-1780
Phytotherapy research : PTR 2024 Apr;38(4):1761-1780
Integrated network pharmacology, molecular docking and pharmacodynamic study reveals protective effects and mechanisms of corilagin against cerebral ischemia-induced injury.
Tao D, Xia X, Zhang X, Yang R, Yang Y, Zhang L, Shi Y, Lv D, Chen P, He B, Shen Z
Experimental neurology 2024 Apr;374:114697
Experimental neurology 2024 Apr;374:114697
Sulfasalazine promotes ferroptosis through AKT-ERK1/2 and P53-SLC7A11 in rheumatoid arthritis.
Zhao C, Yu Y, Yin G, Xu C, Wang J, Wang L, Zhao G, Ni S, Zhang H, Zhou B, Wang Y
Inflammopharmacology 2024 Apr;32(2):1277-1294
Inflammopharmacology 2024 Apr;32(2):1277-1294
BDE-47-induced damage prevented by melatonin in grass carp hepatocytes (L8824).
Shan J, Guan H, Zhang Z, Ma W, Cai J, Gao G, Zhang Z
Environmental science and pollution research international 2024 Apr;31(17):26089-26098
Environmental science and pollution research international 2024 Apr;31(17):26089-26098
Astragaloside IV combined with ligustrazine ameliorates abnormal mitochondrial dynamics via Drp1 SUMO/deSUMOylation in cerebral ischemia-reperfusion injury.
Chen X, Yang T, Zhou Y, Mei Z, Zhang W
CNS neuroscience & therapeutics 2024 Apr;30(4):e14725
CNS neuroscience & therapeutics 2024 Apr;30(4):e14725
GPX4-mediated bone ferroptosis under mechanical stress decreased bone formation via the YAP-TEAD signalling pathway.
Mengjia W, Jun J, Xin Z, Jiahao Z, Jie G
Journal of cellular and molecular medicine 2024 Apr;28(7):e18231
Journal of cellular and molecular medicine 2024 Apr;28(7):e18231
Anionic polysaccharides benefit the bioavailability of pork myofibrillar protein gels: Evidence from a perspective of protein absorption and metabolism.
Yu X, Nie W, Chen X, Zou LF, Xu BC, Chen CG
International journal of biological macromolecules 2024 Apr;263(Pt 1):130246
International journal of biological macromolecules 2024 Apr;263(Pt 1):130246
SARS-CoV-2 virus-like particle variants alpha and delta mimic the native viruses in their differential inflammasome activating potential.
Bandyszewska M, Ambrożek-Latecka M, Hoser G, Grzanka M, Hornung F, Deinhardt-Emmer S, Skirecki T
Antiviral research 2024 Apr;224:105857
Antiviral research 2024 Apr;224:105857
Hydrogen sulfide improves endothelial barrier function by modulating the ubiquitination degradation of KLF4 through TRAF7 S-sulfhydration in diabetic aorta.
Li Q, Kang J, Liu N, Huang J, Zhang X, Pang K, Zhang S, Wang M, Zhao Y, Dong S, Li H, Zhao D, Lu F, Zhang W
Free radical biology & medicine 2024 Apr;216:118-138
Free radical biology & medicine 2024 Apr;216:118-138
Tris-Functionalized Polyoxotungstovanadate-Mediated Antitumor Efficacy Involves Multiple Cell Death Pathways.
Chen L, Zhao Z, Diarimalala RO, Chen Z, Wang Y, Zhan T, Zhao Y, Ma C, Wang X, Zhao C, Xiao Z, Hu K, Wu P
Chemistry & biodiversity 2024 Apr;21(4):e202301898
Chemistry & biodiversity 2024 Apr;21(4):e202301898
Mitigation effect of hesperidin on X-ray radiation-induced intestinal barrier dysfunction in Caco-2 cell monolayers.
Park HY, Yu JH
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114549
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114549
Synergistic effect of cannabidiol with dasatinib on lung cancer by SRC/PI3K/AKT signal pathway.
Ye Q, Gui C, Jin D, Zhang J, Zhang J, Ma N, Xu L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Apr;173:116445
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Apr;173:116445
Inhibition of PTPRE suppresses tumor progression and improves sorafenib response in hepatocellular carcinoma.
Dong R, Wang T, Dong W, Zhu H, Liu Q, Liang H, Chen X, Zhang B, Zhang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Apr;173:116366
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Apr;173:116366
The bone-protective benefits of kaempferol combined with metformin by regulation of osteogenesis-angiogenesis coupling in OVX rats.
Zhang Z, Xu W, Zhang Z, Chen X, Jin H, Jiang N, Xu H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Apr;173:116364
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Apr;173:116364
Koumine inhibits IL-1β-induced chondrocyte inflammation and ameliorates extracellular matrix degradation in osteoarthritic cartilage through activation of PINK1/Parkin-mediated mitochondrial autophagy.
Kong X, Ning C, Liang Z, Yang C, Wu Y, Li Y, Wu A, Wang Y, Wang S, Fan H, Xiao W, Wu J, Sun Z, Yuan Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Apr;173:116273
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Apr;173:116273
Deficiency of immunoglobulin IgSF6 enhances antibacterial effects by promoting endoplasmic reticulum stress and the inflammatory response in intestinal macrophages.
Wu Y, Zhang P, Shi T, Cao D, Pan W
Mucosal immunology 2024 Apr;17(2):288-302
Mucosal immunology 2024 Apr;17(2):288-302
Herb pair of Rhubarb-Astragalus mitigates renal interstitial fibrosis through downregulation of autophagy via p38-MAPK/TGF-β1 and p38-MAPK/smad2/3 pathways.
Li J, Qin X, Xu W, Zhang H, Huang S, Yang Y, Qin M, Mi Z, Zhong X
The international journal of biochemistry & cell biology 2024 Apr;169:106549
The international journal of biochemistry & cell biology 2024 Apr;169:106549
CyHV-2 infection triggers mitochondrial-mediated apoptosis in GiCF cells by upregulating the pro-apoptotic gene ccBAX.
Cheng W, Ren Y, Yu C, Zhou T, Zhang Y, Lu L, Liu Y, Xu D
Fish & shellfish immunology 2024 Apr;147:109400
Fish & shellfish immunology 2024 Apr;147:109400
New daphnane diterpenoidal 1,3,4-oxdiazole derivatives as potential anti-hepatoma agents: Synthesis, biological evaluation and molecular modeling studies.
Wang X, Wang Y, Liu Z, Zhao H, Yao GD, Liu Q, Song SJ
Bioorganic chemistry 2024 Apr;145:107208
Bioorganic chemistry 2024 Apr;145:107208
Phenolics and terpenoids with good anti-inflammatory activity from the fruits of Amomum villosum and the anti-inflammatory mechanism of active diterpene.
Xu Y, Sun D, Xiong L, Zhang Z, Li Y, Liu K, Li H, Chen L
Bioorganic chemistry 2024 Apr;145:107190
Bioorganic chemistry 2024 Apr;145:107190
Co-catalpol alleviates fluoxetine-induced main toxicity: Involvement of ATF3/FSP1 signaling-mediated inhibition of ferroptosis.
Wu X, Guan Y, Wang J, Song L, Zhang Y, Wang Y, Li Y, Qin L, He Q, Zhang T, Long B, Ji L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155340
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155340
Neonatal resveratrol administration promotes skeletal muscle growth and insulin sensitivity in intrauterine growth-retarded suckling piglets associated with activation of FGF21-AMPKα pathway.
Bai G, Chen J, Liu Y, Chen J, Yan H, You J, Zou T
Journal of the science of food and agriculture 2024 Apr;104(6):3719-3728
Journal of the science of food and agriculture 2024 Apr;104(6):3719-3728
Effect of immunization against OPN5 on the reproductive performance in Shan Partridge ducks under different photoperiods.
Liu-Fu S, Pan JQ, Sun JF, Shen X, Jiang DL, Ouyang HJ, Xu DN, Tian YB, Huang YM
Poultry science 2024 Apr;103(4):103413
Poultry science 2024 Apr;103(4):103413
Enterohemorrhagic Escherichia coli effector EspF triggers oxidative DNA lesions in intestinal epithelial cells.
Fang Y, Fu M, Li X, Zhang B, Wan C
Infection and immunity 2024 Apr 9;92(4):e0000124
Infection and immunity 2024 Apr 9;92(4):e0000124
UBA2 as a Prognostic Biomarker and Potential Therapeutic Target in Glioma.
Ou Y, Luo H, Zhang Q, Du T, Liu R, Wang D, Chen J, Dong M, Wang Y, Yang Z, Wang X
Frontiers in bioscience (Landmark edition) 2024 Apr 9;29(4):144
Frontiers in bioscience (Landmark edition) 2024 Apr 9;29(4):144
Excessive fat expenditure in MCT-induced heart failure rats is associated with BMAL1/REV-ERBα circadian rhythmic loop disruption.
Ma D, Qu Y, Wu T, Liu X, Cai L, Wang Y
Scientific reports 2024 Apr 7;14(1):8128
Scientific reports 2024 Apr 7;14(1):8128
Jiawei Buzhong Yiqi decoction ameliorates polycystic ovary syndrome via oocyte-granulosa cell communication.
Hu R, Huang Y, Geng Y, Liu Z, Li F, Zhang Z, Ma W, Song K, Dong H, Song Y, Zhang M
Journal of ethnopharmacology 2024 Apr 6;323:117654
Journal of ethnopharmacology 2024 Apr 6;323:117654
Tetrahydroberberine alleviates high-fat diet-induced hyperlipidemia in mice via augmenting lipoprotein assembly-induced clearance of low-density lipoprotein and intermediate-density lipoprotein.
Wei G, Huang N, Li M, Guan F, Chen L, Liao Y, Xie X, Li Y, Su Z, Chen J, Liu Y
European journal of pharmacology 2024 Apr 5;968:176433
European journal of pharmacology 2024 Apr 5;968:176433
Ginsenoside Rg1 promotes fetal hemoglobin production in vitro: A potential therapeutic avenue for β-thalassemia.
Cai DL, Chan Y, Kong YM, Liu YZ, Guo Y, Cai AQ, Zhu BS
European journal of pharmacology 2024 Apr 5;968:176404
European journal of pharmacology 2024 Apr 5;968:176404
Senescent-like macrophages mediate angiogenesis for endplate sclerosis via IL-10 secretion in male mice.
Fan Y, Zhang W, Huang X, Fan M, Shi C, Zhao L, Pi G, Zhang H, Ni S
Nature communications 2024 Apr 5;15(1):2939
Nature communications 2024 Apr 5;15(1):2939
Targeting hepatic ceruloplasmin mitigates nonalcoholic steatohepatitis by modulating bile acid metabolism.
Jiang Q, Wang N, Lu S, Xiong J, Yuan Y, Liu J, Chen S
Journal of molecular cell biology 2024 Apr 4;15(9)
Journal of molecular cell biology 2024 Apr 4;15(9)
POLQ inhibition attenuates the stemness and ferroptosis resistance in gastric cancer cells via downregulation of dihydroorotate dehydrogenase.
Peng Y, Zheng W, Chen Y, Lei X, Yang Z, Yang Y, Liang W, Sun K, Li G, Yu J
Cell death & disease 2024 Apr 4;15(4):248
Cell death & disease 2024 Apr 4;15(4):248
Blockade of PI3K/AKT signaling pathway by Astragaloside IV attenuates ulcerative colitis via improving the intestinal epithelial barrier.
Zhang X, Zhang F, Li Y, Fan N, Zhao K, Zhang A, Kang J, Lin Y, Xue X, Jiang X
Journal of translational medicine 2024 Apr 30;22(1):406
Journal of translational medicine 2024 Apr 30;22(1):406
Neuroprotective effects of takinib on an experimental traumatic brain injury rat model via inhibition of transforming growth factor beta-activated kinase 1.
Hao S, Yuan S, Liu Z, Hou B, Feng S, Zhang D
Heliyon 2024 Apr 30;10(8):e29484
Heliyon 2024 Apr 30;10(8):e29484
Naringenin Inhibits Acid Sphingomyelinase-Mediated Membrane Raft Clustering to Reduce NADPH Oxidase Activation and Vascular Inflammation.
Ding M, Zhu Y, Xu X, He H, Jiang T, Mo X, Wang Z, Yu W, Ou H
Journal of agricultural and food chemistry 2024 Apr 3;72(13):7130-7139
Journal of agricultural and food chemistry 2024 Apr 3;72(13):7130-7139
Electroacupuncture promotes macrophage/microglial M2 polarization and suppresses inflammatory pain through AMPK.
Nan FB, Gu YX, Wang JL, Chen SD
Neuroreport 2024 Apr 3;35(6):343-351
Neuroreport 2024 Apr 3;35(6):343-351
The Lipophilic Extract from Ginkgo biloba L. Leaves Promotes Glucose Uptake and Alleviates Palmitate-Induced Insulin Resistance in C2C12 Myotubes.
Li T, Lv Q, Liu C, Li C, Xie X, Zhang W
Molecules (Basel, Switzerland) 2024 Apr 3;29(7)
Molecules (Basel, Switzerland) 2024 Apr 3;29(7)
Induction of IFIT1/IFIT3 and inhibition of Bcl-2 orchestrate the treatment of myeloma and leukemia via pyroptosis.
He Y, Jiang S, Cui Y, Liang J, Zhong Y, Sun Y, Moran MF, Huang Z, He G, Mao X
Cancer letters 2024 Apr 28;588:216797
Cancer letters 2024 Apr 28;588:216797
Histone Lactylation Is Involved in Mouse Oocyte Maturation and Embryo Development.
Yang D, Zheng H, Lu W, Tian X, Sun Y, Peng H
International journal of molecular sciences 2024 Apr 28;25(9)
International journal of molecular sciences 2024 Apr 28;25(9)
Ginsenoside Rh2 shifts tumor metabolism from aerobic glycolysis to oxidative phosphorylation through regulating the HIF1-α/PDK4 axis in non-small cell lung cancer.
Liu X, Li J, Huang Q, Jin M, Huang G
Molecular medicine (Cambridge, Mass.) 2024 Apr 26;30(1):56
Molecular medicine (Cambridge, Mass.) 2024 Apr 26;30(1):56
Rational Design of a Novel Class of Human ClpP Agonists through a Ring-Opening Strategy with Enhanced Antileukemia Activity.
Xiang X, Dai Z, Luo B, Zhao N, Liu S, Sui J, Huang J, Zhou Y, Gu J, Zhang J, Yang T, Bao R, Luo Y
Journal of medicinal chemistry 2024 Apr 25;67(8):6769-6792
Journal of medicinal chemistry 2024 Apr 25;67(8):6769-6792
Selenium binding protein 1 protects renal tubular epithelial cells from ferroptosis by upregulating glutathione peroxidase 4.
Zhao W, Nikolic-Paterson DJ, Li K, Li Y, Wang Y, Chen X, Duan Z, Zhang Y, Liu P, Lu S, Fu R, Tian L
Chemico-biological interactions 2024 Apr 25;393:110944
Chemico-biological interactions 2024 Apr 25;393:110944
Neuroprotective effect of acetoxypachydiol against oxidative stress through activation of the Keap1-Nrf2/HO-1 pathway.
Qi Y, Liu G, Jin S, Jian R, Zou Z, Wang C, Zhang Y, Zhao M, Zhu H, Yan P
BMC complementary medicine and therapies 2024 Apr 25;24(1):175
BMC complementary medicine and therapies 2024 Apr 25;24(1):175
Exploration the mechanism of Shenling Baizhu San in the treatment of chronic obstructive pulmonary disease based on UPLC-Q-TOF-MS/MS, network pharmacology and in vitro experimental verification.
Gao Z, Wang J, Lu G, Wu Q, Wang S, Wu X, Ou C, Wu Z, Yu H, Wang Y
Journal of ethnopharmacology 2024 Apr 24;324:117728
Journal of ethnopharmacology 2024 Apr 24;324:117728
Oxymatrine Modulation of TLR3 Signaling: A Dual-Action Mechanism for H9N2 Avian Influenza Virus Defense and Immune Regulation.
Zhi Y, Zhao X, Liu Z, Shen G, Zhang T, Zhang T, Hu G
Molecules (Basel, Switzerland) 2024 Apr 24;29(9)
Molecules (Basel, Switzerland) 2024 Apr 24;29(9)
Design, synthesis, and evaluation of novel ferrostatin derivatives for the prevention of HG-induced VEC ferroptosis.
Wang XX, Wang RJ, Ji HL, Liu XY, Zhang NY, Wang KM, Chen K, Liu PP, Meng N, Jiang CS
RSC medicinal chemistry 2024 Apr 24;15(4):1198-1209
RSC medicinal chemistry 2024 Apr 24;15(4):1198-1209
The anti-apoptotic role of Ginkgolide B via mitochondrial permeability transition pore inhibition in retinal ischemia-reperfusion.
Wang X, Hu B, Zhang H, Zhou S, Wu W, Tan Z, Sun M, Kang Q
Biochemical and biophysical research communications 2024 Apr 23;705:149722
Biochemical and biophysical research communications 2024 Apr 23;705:149722
Baicalein alleviates intrahepatic cholestasis by regulating bile acid metabolism via an FXR-dependent manner.
Huang W, Qian Y, Lin J, Wang F, Kong X, Tan W
Biochemical and biophysical research communications 2024 Apr 23;705:149670
Biochemical and biophysical research communications 2024 Apr 23;705:149670
Polar lipids modify Alzheimer's Disease pathology by reducing astrocyte pro-inflammatory signaling through platelet-activating factor receptor (PTAFR) modulation.
Hans S, Stanton JE, Sauer AK, Shiels K, Saha SK, Lordan R, Tsoupras A, Zabetakis I, Grabrucker AM
Lipids in health and disease 2024 Apr 20;23(1):113
Lipids in health and disease 2024 Apr 20;23(1):113
Up-regulation of HSP90α in HDM-induced asthma causes pyroptosis of airway epithelial cells by activating the cGAS-STING-ER stress pathway.
Huang H, Qiao Y, Chu L, Ye C, Lin L, Liao H, Meng X, Zou F, Zhao H, Zou M, Cai S, Dong H
International immunopharmacology 2024 Apr 20;131:111917
International immunopharmacology 2024 Apr 20;131:111917
Protective effects of pulsed electromagnetic field therapy attenuates autophagy and apoptosis in osteoporotic osteoarthritis model rats by activating PPARγ.
Liu J, Zhou J, Huang X, Yin L, Zhou L, Liao Y, Sun G, Zhong P, Peng X, Sun Z
Electromagnetic biology and medicine 2024 Apr 2;43(1-2):61-70
Electromagnetic biology and medicine 2024 Apr 2;43(1-2):61-70
Unveiling the therapeutic potential of Dl-3-n-butylphthalide in NTG-induced migraine mouse: activating the Nrf2 pathway to alleviate oxidative stress and neuroinflammation.
Liu Y, Gong Z, Zhai D, Yang C, Lu G, Wang S, Xiao S, Li C, Chen L, Lin X, Zhang S, Yu S, Dong Z
The journal of headache and pain 2024 Apr 2;25(1):50
The journal of headache and pain 2024 Apr 2;25(1):50
Necl-1/CADM3 regulates cone synapse formation in the mouse retina.
Kawashima R, Matsushita K, Mandai K, Sugita Y, Maruo T, Mizutani K, Midoh Y, Oguchi A, Murakawa Y, Kuniyoshi K, Sato R, Furukawa T, Nishida K, Takai Y
iScience 2024 Apr 19;27(4):109577
iScience 2024 Apr 19;27(4):109577
Identification and verification of the role of key metabolites and metabolic pathways on ASFV replication.
Shi Z, Yang X, Shi X, Zhang D, Zhao D, Hao Y, Yang J, Bie X, Yan W, Chen G, Chen L, Liu X, Zheng H, Zhang K
iScience 2024 Apr 19;27(4):109345
iScience 2024 Apr 19;27(4):109345
An LRPPRC-HAPSTR1-PSMD14 interaction regulates tumor progression in ovarian cancer.
Li D, Wang M
Aging 2024 Apr 18;16(8):6773-6795
Aging 2024 Apr 18;16(8):6773-6795
Noninvasive Monitoring of Early Cardiac Fibrosis in Diabetic Mice by [(68)Ga]Ga-DOTA-FAPI-04 PET/CT Imaging.
Lin K, Shi D, Wang A, Ge J, Cheng D, Yan Y
ACS omega 2024 Apr 16;9(15):17195-17203
ACS omega 2024 Apr 16;9(15):17195-17203
Intratumor microbiome-derived butyrate promotes lung cancer metastasis.
Ma Y, Chen H, Li H, Zheng M, Zuo X, Wang W, Wang S, Lu Y, Wang J, Li Y, Wang J, Qiu M
Cell reports. Medicine 2024 Apr 16;5(4):101488
Cell reports. Medicine 2024 Apr 16;5(4):101488
Suppression of hypoxia-induced CAV1 autophagic degradation enhances nanoalbumin-paclitaxel transcytosis and improves therapeutic activity in pancreatic cancer.
Bai X, Xiong J, Li L, Yu C, Sun C
European journal of pharmacology 2024 Apr 15;969:176431
European journal of pharmacology 2024 Apr 15;969:176431
Human Umbilical Cord Mesenchymal Stromal Cell-Derived Exosomes Alleviate Hypoxia-Induced Pulmonary Arterial Hypertension in Mice Via Macrophages.
Liu H, Zhang Q, Liu C, Zhang Y, Wang Y, Huang P, Ma L, Ge R
Stem cells (Dayton, Ohio) 2024 Apr 15;42(4):329-345
Stem cells (Dayton, Ohio) 2024 Apr 15;42(4):329-345
Liquiritin reduces chondrocyte apoptosis through P53/PUMA signaling pathway to alleviate osteoarthritis.
Qiu M, Cheng L, Xu J, Jin M, Yuan W, Ge Q, Zou K, Chen J, Huang Y, Li J, Zhu L, Xu B, Zhang C, Jin H, Wang P
Life sciences 2024 Apr 15;343:122536
Life sciences 2024 Apr 15;343:122536
13-oxyingenol dodecanoate derivatives induce mitophagy and ferroptosis through targeting TMBIM6 as potential anti-NSCLC agents.
Wang Y, Gu L, Li J, Wang R, Zhuang Y, Li X, Wang X, Zhang J, Liu Q, Wang J, Song SJ
European journal of medicinal chemistry 2024 Apr 15;270:116312
European journal of medicinal chemistry 2024 Apr 15;270:116312
Dapagliflozin ameliorates myocardial infarction injury through AMPKα-dependent regulation of oxidative stress and apoptosis.
Peng Y, Guo M, Luo M, Lv D, Liao K, Luo S, Zhang B
Heliyon 2024 Apr 15;10(7):e29160
Heliyon 2024 Apr 15;10(7):e29160
Acupoints catgut embedding recovers leptin resistance via improving autophagy progress mediated by AMPK-mTOR signaling in obese mice.
Xiong Y, Wang X, Gong M, Ji Q, Li Y, Hu A, Lu M, Xu B
Heliyon 2024 Apr 15;10(7):e29094
Heliyon 2024 Apr 15;10(7):e29094
METTL3 mediates SOX5 m6A methylation in bronchial epithelial cells to attenuate Th2 cell differentiation in T2 asthma.
Chen Z, Shang Y, Zhang X, Duan W, Li J, Zhu L, Ma L, Xiang X, Jia J, Ji X, Gong S
Heliyon 2024 Apr 15;10(7):e28884
Heliyon 2024 Apr 15;10(7):e28884
Phosphoglycerate mutase 5 exacerbates liver ischemia-reperfusion injury by activating mitochondrial fission.
Tang H, Yu Q, Chen X, Zhang J, Guo D, Guo W, Zhang S, Shi X
Scientific reports 2024 Apr 12;14(1):8535
Scientific reports 2024 Apr 12;14(1):8535
Rat Hepatocytes Protect against Lead-Cadmium-Triggered Apoptosis Based on Autophagy Activation.
Xue J, Liu H, Yin T, Zhou X, Song X, Zou Y, Li L, Jia R, Fu Y, Zhao X, Yin Z
Toxics 2024 Apr 12;12(4)
Toxics 2024 Apr 12;12(4)
Zearalenone Decreases Food Intake by Disrupting the Gut-Liver-Hypothalamus Axis Signaling via Bile Acids.
Yuan P, Ma R, Hu L, Li R, Wang P, Lin S, Huang J, Wen H, Huang L, Li H, Feng B, Chen H, Liu Y, Zhang X, Lin Y, Xu S, Li J, Zhuo Y, Hua L, Che L, Wu D, Fang Z
Journal of agricultural and food chemistry 2024 Apr 10;72(14):8200-8213
Journal of agricultural and food chemistry 2024 Apr 10;72(14):8200-8213
Icaritin with autophagy/mitophagy inhibitors synergistically enhances anticancer efficacy and apoptotic effects through PINK1/Parkin-mediated mitophagy in hepatocellular carcinoma.
Luo P, An Y, He J, Xing X, Zhang Q, Liu X, Chen Y, Yuan H, Chen J, Wong YK, Huang J, Gong Z, Du Q, Xiao W, Wang J
Cancer letters 2024 Apr 10;587:216621
Cancer letters 2024 Apr 10;587:216621
CGRP Released by Corneal Sensory Nerve Maintains Tear Secretion of the Lacrimal Gland.
Ma L, Yang L, Wang X, Zhao L, Bai X, Qi X, Chen Q, Li Y, Zhou Q
Investigative ophthalmology & visual science 2024 Apr 1;65(4):30
Investigative ophthalmology & visual science 2024 Apr 1;65(4):30
PARP inhibitor plus radiotherapy reshape the immune suppressive microenvironment and potentiate the efficacy of immune checkpoint inhibitors in tumors with IDH1 mutation.
Hu X, Zhao M, Bai M, Xue Z, Wang F, Zhu Z, Yu J, Yue J
Cancer letters 2024 Apr 1;586:216676
Cancer letters 2024 Apr 1;586:216676
High level 27-HC impairs trophoblast cell invasion and migration via LXR in pre-eclampsia.
Tong H, Wang T, Chen R, Jin P, Jiang Y, Zhang X, Qi H
Experimental cell research 2024 Apr 1;437(1):113979
Experimental cell research 2024 Apr 1;437(1):113979
Human gestational diabetes mellitus-derived exosomes impair glucose homeostasis in pregnant mice and stimulate functional maturation of offspring-islets.
Zou L, Xu C, Wang L, Cao X, Jia X, Yang Z, Jiang G, Ji L
Life sciences 2024 Apr 1;342:122514
Life sciences 2024 Apr 1;342:122514
A chemo/chemodynamic nanoparticle based on hyaluronic acid induces ferroptosis and apoptosis for triple-negative breast cancer therapy.
Wang N, Zhang Q, Wang Z, Liu Y, Yang S, Zhao X, Peng J
Carbohydrate polymers 2024 Apr 1;329:121795
Carbohydrate polymers 2024 Apr 1;329:121795
Adhesive hydrogel releases protocatechualdehyde-Fe(3+) complex to promote three healing stages for accelerated therapy of oral ulcers.
Wang Y, Pan Z, Cui J, Zhang X, Li D, Sun H, Yang B, Li Y
Acta biomaterialia 2024 Apr 1;178:68-82
Acta biomaterialia 2024 Apr 1;178:68-82
Senktide blocks aberrant RTN3 interactome to retard memory decline and tau pathology in social isolated Alzheimer's disease mice.
Huang HZ, Ai WQ, Wei N, Zhu LS, Liu ZQ, Zhou CW, Deng MF, Zhang WT, Zhang JC, Yang CQ, Hu YZ, Han ZT, Zhang HH, Jia JJ, Wang J, Liu FF, Li K, Xu Q, Yuan M, Man H, Guo Z, Lu Y, Shu K, Zhu LQ, Liu D
Protein & cell 2024 Apr 1;15(4):261-284
Protein & cell 2024 Apr 1;15(4):261-284
LncRNA GAS5 restrains ISO-induced cardiac fibrosis by modulating mir-217 regulation of SIRT1.
Zhang YH, Sun TT, Liu ZH, Li X, Fan XF, Han LP
Scientific reports 2024 Apr 1;14(1):7652
Scientific reports 2024 Apr 1;14(1):7652
Liquiritigenin Attenuated Collagen-Induced Arthritis and Cardiac Complication via Inflammation and Fibrosis Inhibition in Mice.
Ning X, Ni Y, Cao J, Zhang H
Chemical & pharmaceutical bulletin 2023;71(4):269-276
Chemical & pharmaceutical bulletin 2023;71(4):269-276
Lin28B overexpression decreases let-7b and let-7g levels and increases proliferation and estrogen secretion in Dolang sheep ovarian granulosa cells.
Sui Z, Zhang Y, Zhang Z, Wang C, Li X, Xing F
Archives animal breeding 2023;66(3):217-224
Archives animal breeding 2023;66(3):217-224
Nanoengineered Gallium Ion Incorporated Formulation for Safe and Efficient Reversal of PARP Inhibition and Platinum Resistance in Ovarian Cancer.
Li Y, Cen Y, Tu M, Xiang Z, Tang S, Lu W, Zhang H, Xu J
Research (Washington, D.C.) 2023;6:0070
Research (Washington, D.C.) 2023;6:0070
Mechanisms of resveratrol against diabetic wound by network pharmacology and experimental validation.
Youjun D, Huang Y, Lai Y, Ma Z, Wang X, Chen B, Ding X, Tan Q
Annals of medicine 2023;55(2):2280811
Annals of medicine 2023;55(2):2280811
Maslinic Acid Ameliorates Myocardial Ischemia Reperfusion Injury-Induced Oxidative Stress via Activating Nrf2 and Inhibiting NF-[Formula: see text]B Pathways.
Li Q, Li Z, Liu C, Xu M, Li T, Wang Y, Feng J, Yin X, Du X, Lu C
The American journal of Chinese medicine 2023;51(4):929-951
The American journal of Chinese medicine 2023;51(4):929-951
MiR-328-3p promotes TGF-β1-induced proliferation, migration, and inflammation of airway smooth muscle cells by regulating the PTEN/Akt pathway.
Gao J, Wu XL
Allergologia et immunopathologia 2023;51(2):151-159
Allergologia et immunopathologia 2023;51(2):151-159
Inhibition of cGAS aggravated the host inflammatory response to Aspergillus fumigatus.
Peng M, Li X, Zhang X, Peng L
Experimental lung research 2023;49(1):86-100
Experimental lung research 2023;49(1):86-100
The mechanism of monobutyl phthalate -induced ferroptosis via TNF/IL6/STAT3 signal pathway in TM-3 cells.
Guo X, Hao Y, Ma H, Li H, Li L, Yan F, Huang J, Li L
The Journal of toxicological sciences 2023;48(5):299-310
The Journal of toxicological sciences 2023;48(5):299-310
A Novel Myricetin Derivative with Anti-cancer Properties Induces Cell Cycle Arrest and Apoptosis in A549 Cells.
Zhou H, Xu L, Shi Y, Gu S, Wu N, Liu F, Huang Y, Qian Z, Xue W, Wang X, Chen F
Biological & pharmaceutical bulletin 2023;46(1):42-51
Biological & pharmaceutical bulletin 2023;46(1):42-51
Absent in melanoma 2 attenuates proliferation and migration and promotes apoptosis of human colorectal cancer cells by activating P38MAPK signaling pathway.
Zhang Z, Li X, Zhang Y, Zhu H, Qiao Z, Lu Y, Mi X, Cao H, Shen G, He S
Oncology research 2023;32(2):353-360
Oncology research 2023;32(2):353-360
MiR-124 Reduced Neuroinflammation after Traumatic Brain Injury by Inhibiting TRAF6.
Yang Y, Ye Y, Fan K, Luo J, Yang Y, Ma Y
Neuroimmunomodulation 2023;30(1):55-68
Neuroimmunomodulation 2023;30(1):55-68
Inhibition of Galectin-3 in a Rat Model of Epilepsy and Kainate-Activated BV2 Cells Limits Microglial Activation Through the NLRP3/Pyroptosis Pathway.
Sun W, Hao Y, Li C, Zhao Y, Yu H, Wang L
Neuroimmunomodulation 2023;30(1):325-337
Neuroimmunomodulation 2023;30(1):325-337
Considering the protective effect of exendin-4 against oxidative stress in spiral ganglion neurons.
Wu H, Ou Y, Wang S, Yu F, Fan X, Kang H, Chen T
Iranian journal of basic medical sciences 2023;26(12):1423-1430
Iranian journal of basic medical sciences 2023;26(12):1423-1430
Persistent Müllerian duct syndrome in an assisted reproductive patient: a novel variant impairs the biosynthesis and secretion of anti-Müllerian hormone (AMH).
Du Q, Qiu C, Zhang L, Wang QY, Hong K, Liu XL
Asian journal of andrology 2023;25(4):534-536
Asian journal of andrology 2023;25(4):534-536
Exosomes derived from BMSCs ameliorate cyclophosphamide-induced testosterone deficiency by enhancing the autophagy of Leydig cells via the AMPK-mTOR signaling pathway.
Liang HY, Peng F, Pan MJ, Liao SL, Wei C, Wei GY, Xie X, Xue KY, Chen MK, Yang JK, Guo WB, Liu CD, Zhou QZ
Asian journal of andrology 2023;25(4):474-483
Asian journal of andrology 2023;25(4):474-483
Montelukast Inhibits Lung Cancer Cell Migration by Suppressing Cysteinyl Leukotriene Receptor 1 Expression In vitro.
Chen Y, Zhang J, Wei S
Current pharmaceutical biotechnology 2023;24(10):1335-1342
Current pharmaceutical biotechnology 2023;24(10):1335-1342
Static Magnetic Field Promotes Proliferation, Migration, Differentiation, and AKT Activation of Periodontal Ligament Stem Cells.
Zhang K, Ge W, Luo S, Zhou Z, Liu Y
Cells, tissues, organs 2023;212(4):317-326
Cells, tissues, organs 2023;212(4):317-326
OL-FS13 Alleviates Cerebral Ischemia-reperfusion Injury by Inhibiting miR-21-3p Expression.
Liu N, Fan Y, Li Y, Zhang Y, Li J, Wang Y, Wang Z, Liu Y, Li Y, Kang Z, Peng Y, Ru Z, Yang M, Feng C, Wang Y, Yang X
Current neuropharmacology 2023;21(12):2550-2562
Current neuropharmacology 2023;21(12):2550-2562
Up-regulated SPP1 increases the risk from IPF to lung cancer via activating the pro-tumor macrophages.
Chen T, Guo J, Ai L, Wang Y, Wang Y, Chen B, Liu M, Zhuang S, Liu K, Zhao Z, Liang H, Gu Y
Computational and structural biotechnology journal 2023;21:5751-5764
Computational and structural biotechnology journal 2023;21:5751-5764
RRP Regulates Autophagy through the AMPK Pathway to Alleviate the Effect of Cell Senescence on Atherosclerosis.
Liu D, Song Y, Song T, Lin L, Zhang L, Yang Q, Niu X, Liang D, Yin J, Yang W, Zhang D
Oxidative medicine and cellular longevity 2023;2023:9645789
Oxidative medicine and cellular longevity 2023;2023:9645789
miR-145 Alleviates Smooth Muscle Cell Phenotype Transition via ADAM17-Mediated ACE2 Shedding.
Wen J, Tang B, Guo L, Chen W, Tang X
International journal of hypertension 2023;2023:9497716
International journal of hypertension 2023;2023:9497716
Diet Control and Swimming Exercise Ameliorate HFD-Induced Cognitive Impairment Related to the SIRT1-NF-κB/PGC-1α Pathways in ApoE-/- Mice.
Wei W, Lin Z, Xu P, Lv X, Lin L, Li Y, Zhou Y, Lu T, Xue X
Neural plasticity 2023;2023:9206875
Neural plasticity 2023;2023:9206875
A Water-Soluble Hydrogen Sulfide Donor Suppresses the Growth of Hepatocellular Carcinoma via Inhibiting the AKT/GSK-3β/β-Catenin and TGF-β/Smad2/3 Signaling Pathways.
Duan SF, Zhang MM, Dong Q, Yang B, Liu W, Zhang X, Yu HL, Zhang SH, Khan NH, Wu DD, Zhang XJ, Cen J
Journal of oncology 2023;2023:8456852
Journal of oncology 2023;2023:8456852
Plumbagin Enhances the Anticancer Effects of PF Chemotherapy via Downregulation of the PI3K/AKT/mTOR/p70S6K Pathway in Human Tongue Squamous Cell Carcinoma.
Pan ST, Ye FF, Huang G, Qiu JX
Journal of oncology 2023;2023:8306514
Journal of oncology 2023;2023:8306514
Jia-Wei-Kai-Xin-San Treatment Alleviated Mild Cognitive Impairment through Anti-Inflammatory and Antiapoptotic Mechanisms in SAMP8 Mice.
Zhang X, Sun Y, Yu Q, Zeng W, Zhang Y, Zeng M, Pang K, Yu Y, Gan J, Li H, Yang L, Jiang X
Mediators of inflammation 2023;2023:7807302
Mediators of inflammation 2023;2023:7807302
Empagliflozin-Pretreated Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Attenuated Heart Injury.
Chi B, Zou A, Mao L, Cai D, Xiao T, Wang Y, Wang Q, Ji Y, Sun L
Oxidative medicine and cellular longevity 2023;2023:7747727
Oxidative medicine and cellular longevity 2023;2023:7747727
Cartilage Damage Pathological Characteristics of Diabetic Neuropathic Osteoarthropathy.
Liu PL, Diao JY, Wang Q, Liu H, Zhang Y, Liang JQ, Zhang F, Liang XJ, Zhao HM
Analytical cellular pathology (Amsterdam) 2023;2023:7573165
Analytical cellular pathology (Amsterdam) 2023;2023:7573165
IFN-α-2b Reduces Postoperative Arthrofibrosis in Rats by Inhibiting Fibroblast Proliferation and Migration through STAT1/p21 Signaling Pathway.
Liu Z, Fan Z, Wang R, Li X, Chen H, Wang J
Mediators of inflammation 2023;2023:1699946
Mediators of inflammation 2023;2023:1699946
Adjuvant Efficacy of the ECMS-Oil on Immune Responses against Bordetella bronchiseptica in Mice through the TLR2/MyD88/NF-κB Pathway.
Xiao C, Huang Y, Cui X, Wei Q, Ji Q, Liu Y, Fei S, Pan Y, Xu X, Pan H, Bao G
Journal of immunology research 2023;2023:1011659
Journal of immunology research 2023;2023:1011659
TRPM2 facilitates tumor progression of clear cell renal cell carcinoma by relieving Endoplasmic Reticulum Stress.
Yuan H, Li W, Lou N, Yu T, Meng X, Xiao W, Zhang X
International journal of medical sciences 2023;20(1):57-69
International journal of medical sciences 2023;20(1):57-69
Quantitative Measurement of Transthyretin Mistargeting by Proximity Labeling and Parallel Reaction Monitoring.
Lyu Z, Genereux JC
Frontiers in chemical biology 2023;2
Frontiers in chemical biology 2023;2
Sphingosine-1-Phosphate Receptor 4 Attenuates Neutrophilic Airway Inflammation in Experimental Asthma via Repressing Proinflammatory Macrophage Activation.
Wang S, Tian Z, Lu Y, Huang Z, Fan Y, Li B, Zheng H, Wu X, Wang M, Zhao J, Xie J
International journal of biological sciences 2023;19(5):1597-1615
International journal of biological sciences 2023;19(5):1597-1615
Antioxioxidant and antiapoptotic effects of Thymosin β4 in Aβ-induced SH-SY5Y cells via the 5-HTR1A/ERK axis.
Zhang GH, Chin KL, Yan SY, Pare R
PloS one 2023;18(10):e0287817
PloS one 2023;18(10):e0287817
Thalidomide Alleviates Apoptosis, Oxidative Damage and Inflammation Induced by Pemphigus Vulgaris IgG in HaCat Cells and Neonatal Mice Through MyD88.
Luan C, Lu Z, Chen J, Chen M, Zhao R, Li X
Drug design, development and therapy 2023;17:2821-2839
Drug design, development and therapy 2023;17:2821-2839
Zhiqiao Gancao Decoction Ameliorates Hyperalgesia in Lumbar Disc Herniation via the CCL2/CCR2 Signaling Pathway.
Huang Z, Lu B, Zhang X, Wang J, Cai X, Liu Y, Mo J, Li Y, Xu B, Shen X
Drug design, development and therapy 2023;17:2239-2257
Drug design, development and therapy 2023;17:2239-2257
ZEB1 Transcriptionally Activates PHGDH to Facilitate Carcinogenesis and Progression of HCC.
Wang H, Lin F, Xu Z, Yu S, Li G, Liao S, Zhao W, Zhang F, Wang J, Wang S, Ouyang C, Zhang C, Xia H, Wu Y, Jiang B, Li Q
Cellular and molecular gastroenterology and hepatology 2023;16(4):541-556
Cellular and molecular gastroenterology and hepatology 2023;16(4):541-556
GW4869 Can Inhibit Epithelial-Mesenchymal Transition and Extracellular HSP90α in Gefitinib-Sensitive NSCLC Cells.
Wan X, Fang Y, Du J, Cai S, Dong H
OncoTargets and therapy 2023;16:913-922
OncoTargets and therapy 2023;16:913-922
18β-Glycyrrhetinic Acid Alleviates P. multocida-Induced Vascular Endothelial Inflammation by PARP1-Mediated NF-κB and HMGB1 Signalling Suppression in PIEC Cells.
Lu Q, Han W, Wen D, Guo P, Liu Y, Wu Z, Fu S, Ye C, Wang X, Qiu Y
Infection and drug resistance 2023;16:4201-4212
Infection and drug resistance 2023;16:4201-4212
Profilin1 Promotes Renal Tubular Epithelial Cell Apoptosis in Diabetic Nephropathy Through the Hedgehog Signaling Pathway.
Mai L, He G, Chen J, Zhu J, Chen S, Yang H, Zhang M, Hou X, Ke M, Li X
Diabetes, metabolic syndrome and obesity : targets and therapy 2023;16:1731-1743
Diabetes, metabolic syndrome and obesity : targets and therapy 2023;16:1731-1743
Exogenous Hydrogen Sulfide Induces A375 Melanoma Cell Apoptosis Through Overactivation of the Unfolded Protein Response.
Ma W, Zhang X, Zhuang L
Clinical, cosmetic and investigational dermatology 2023;16:1641-1651
Clinical, cosmetic and investigational dermatology 2023;16:1641-1651
Dysfunction of inhibitory interneurons contributes to synaptic plasticity via GABABR-pNR2B signaling in a chronic migraine rat model.
Zeng X, Niu Y, Qin G, Zhang D, Chen L
Frontiers in molecular neuroscience 2023;16:1142072
Frontiers in molecular neuroscience 2023;16:1142072
Resveratrol suppresses neuroinflammation to alleviate mechanical allodynia by inhibiting Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway in a rat model of spinal cord injury.
Han J, Hua Z, Yang WJ, Wang S, Yan F, Wang JN, Sun T
Frontiers in molecular neuroscience 2023;16:1116679
Frontiers in molecular neuroscience 2023;16:1116679
Irisin Ameliorates PM2.5-Induced Acute Lung Injury by Regulation of Autophagy Through AMPK/mTOR Pathway.
Ma J, Han Z, Jiao R, Yuan G, Ma C, Yan X, Meng A
Journal of inflammation research 2023;16:1045-1057
Journal of inflammation research 2023;16:1045-1057
Increasing autophagy ameliorates all-trans-retinal-activated NLRP3 inflammasomes in human THP-1 macrophages.
Xia Q, Li J, Zhang L, Zhou Y, Yang Z, Xie J
American journal of translational research 2023;15(6):4380-4389
American journal of translational research 2023;15(6):4380-4389
Long non-coding RNA LINC00707, a prognostic marker, regulates cell proliferation, apoptosis, and EMT in esophageal squamous cell carcinoma.
Gao N, Jiang G, Gao Z, Cui M, Li J, Liu H, Fan T
American journal of translational research 2023;15(4):2426-2442
American journal of translational research 2023;15(4):2426-2442
Inhibition of Piezo1 Ameliorates Intestinal Inflammation and Limits the Activation of Group 3 Innate Lymphoid Cells in Experimental Colitis.
Liu C, Xia Y, Fu S, Meng F, Feng B, Xu L, Li L, Zuo X
Journal of innate immunity 2023;15(1):709-723
Journal of innate immunity 2023;15(1):709-723
Large-Scale Identification of Lysine Crotonylation Reveals Its Potential Role in Oral Squamous Cell Carcinoma.
Yin X, Zhang H, Wei Z, Wang Y, Han S, Zhou M, Xu W, Han W
Cancer management and research 2023;15:1165-1179
Cancer management and research 2023;15:1165-1179
A Y374X TDP43 truncation leads to an altered metabolic profile in amyotrophic lateral sclerosis fibroblasts driven by pyruvate and TCA cycle intermediate alterations.
Allen SP, Al Sultan A, Kabucho Kibirige E, Tonkiss E, Hamer KJ, Castelli LM, Lin YH, Roscoe S, Stefanidis N, Mead RJ, Highley JR, Cooper-Knock J, Hautbergue GM, Heath PR, Kirby J, Shaw PJ
Frontiers in aging neuroscience 2023;15:1151848
Frontiers in aging neuroscience 2023;15:1151848
APEX1 predicts poor prognosis of gallbladder cancer and affects biological properties of CD133(+) GBC-SD cells via upregulating Jagged1.
Wu Z, Liu Z, Sun Y, Yuan Y, Zou Q, Wen Y, Luo J, Liu R
Journal of Cancer 2023;14(8):1443-1457
Journal of Cancer 2023;14(8):1443-1457
MUC15 is an independent prognostic factor that promotes metastases of MYCN non-amplified neuroblastoma.
Guo H, Zhang WX, Zhang QY, Li M, Wang HY, Li D, Liu J, Zhuo Z, He J, Miao L, Xia H
Journal of Cancer 2023;14(18):3496-3507
Journal of Cancer 2023;14(18):3496-3507
Cyclin dependent kinase 14 as a paclitaxel-resistant marker regulated by the TGF-β signaling pathway in human ovarian cancer.
Guan W, Yuan J, Li X, Gao X, Wang F, Liu H, Shi J, Xu G
Journal of Cancer 2023;14(13):2538-2551
Journal of Cancer 2023;14(13):2538-2551
Leveraging a gene signature associated with disulfidptosis identified by machine learning to forecast clinical outcomes, immunological heterogeneities, and potential therapeutic targets within lower-grade glioma.
Zhou Y, Cao Y, Liu W, Wang L, Kuang Y, Zhou Y, Chen Q, Cheng Z, Huang H, Zhang W, Jiang X, Wang B, Ren C
Frontiers in immunology 2023;14:1294459
Frontiers in immunology 2023;14:1294459
Design, synthesis, and evaluation of 4-(3-(3,5-dimethylisoxazol-4-yl)benzyl)phthalazin-1(2H)-one derivatives: potent BRD4 inhibitors with anti-breast cancer activity.
Li Y, Chu X, Yin Y, Li H, Fu H, Feng X, Deng Y, Ge J
Frontiers in pharmacology 2023;14:1289003
Frontiers in pharmacology 2023;14:1289003
Shikimic acid (SA) inhibits neuro-inflammation and exerts neuroprotective effects in an LPS-induced in vitro and in vivo model.
Bao X, Zheng Z, Lv J, Bao J, Chang S, Jiang X, Xin Y
Frontiers in pharmacology 2023;14:1265571
Frontiers in pharmacology 2023;14:1265571
High expression of P-selectin induces neutrophil extracellular traps via the PSGL-1/Syk/Ca(2+)/PAD4 pathway to exacerbate acute pancreatitis.
Xu Q, Shi M, Ding L, Xia Y, Luo L, Lu X, Zhang X, Deng DYB
Frontiers in immunology 2023;14:1265344
Frontiers in immunology 2023;14:1265344
Design and synthesis of cabotegravir derivatives bearing 1,2,3-triazole and evaluation of anti-liver cancer activity.
Xie H, Mao L, Fan G, Wu Z, Wang Y, Hou X, Wang J, Wang H, Liu L, Li S
Frontiers in pharmacology 2023;14:1265289
Frontiers in pharmacology 2023;14:1265289
Midgut microbiota affects the intestinal barrier by producing short-chain fatty acids in Apostichopus japonicus.
Song M, Zhang Z, Li Y, Xiang Y, Li C
Frontiers in microbiology 2023;14:1263731
Frontiers in microbiology 2023;14:1263731
Unveiling the role of hypoxic macrophage-derived exosomes in driving colorectal cancer progression.
Jiang J, Wang W, Zhu L, Shi B, Chen Y, Xia Y, Feng W, Yao W, Lu A, Zhang H
Frontiers in immunology 2023;14:1260638
Frontiers in immunology 2023;14:1260638
METTL3 promotes drug resistance to oxaliplatin in gastric cancer cells through DNA repair pathway.
Wang Y, Hong Z, Song J, Zhong P, Lin L
Frontiers in pharmacology 2023;14:1257410
Frontiers in pharmacology 2023;14:1257410
Anti-inflammatory and analgesic effects of Streblus indicus.
Xie YQ, Huang JY, Chen YX, Zhou Q, Zhou QX, Yang ZY, Xu SK, Tan WH, Liu L
Frontiers in pharmacology 2023;14:1249234
Frontiers in pharmacology 2023;14:1249234
Porcine epidemic diarrhea virus causes diarrhea by activating EGFR to regulates NHE3 activity and mobility on plasma membrane.
Zhang Y, Zhang S, Sun Z, Liu X, Liao G, Niu Z, Kan Z, Xu S, Zhang J, Zou H, Zhang X, Song Z
Frontiers in microbiology 2023;14:1237913
Frontiers in microbiology 2023;14:1237913
18-α-glycyrrhetinic acid alleviates oxidative damage in periodontal tissue by modulating the interaction of Cx43 and JNK/NF-κB pathways.
Cao N, Liu X, Hou Y, Deng Y, Xin Y, Xin X, Xiang X, Liu X, Yu W
Frontiers in pharmacology 2023;14:1221053
Frontiers in pharmacology 2023;14:1221053
Glucosyl hesperidin exhibits more potent anxiolytic activity than hesperidin accompanied by the attenuation of noradrenaline induction in a zebrafish model.
Nishida T, Horita C, Imagawa M, Hibarino M, Tateno S, Kubo Y, Kawabe M, Morishita N, Endo S, Shiozaki K
Frontiers in pharmacology 2023;14:1213252
Frontiers in pharmacology 2023;14:1213252
Effect of arsenic stress on the intestinal structural integrity and intestinal flora abundance of Cyprinus carpio.
Shi X, Xu W, Che X, Cui J, Shang X, Teng X, Jia Z
Frontiers in microbiology 2023;14:1179397
Frontiers in microbiology 2023;14:1179397
A new acid isolated from V. negundo L. inhibits NLRP3 inflammasome activation and protects against inflammatory diseases.
Di Q, Zhao X, Lin J, Li X, Li X, Tang H, Zhang R, Xiao W, Chen W
Frontiers in immunology 2023;14:1174463
Frontiers in immunology 2023;14:1174463
Transcriptomic and functional analyses reveal the molecular mechanisms underlying Fe-mediated tobacco resistance to potato virus Y infection.
Xu C, Guo H, Li R, Lan X, Zhang Y, Xie Q, Zhu D, Mu Q, Wang Z, An M, Xia Z, Wu Y
Frontiers in plant science 2023;14:1163679
Frontiers in plant science 2023;14:1163679
Integrated analysis of cell-specific gene expression in peripheral blood using ISG15 as a marker of rejection in kidney transplantation.
Zhang Z, Qin Y, Wang Y, Li S, Hu X
Frontiers in immunology 2023;14:1153940
Frontiers in immunology 2023;14:1153940
NADPH-dependent ROS accumulation contributes to the impaired osteogenic differentiation of periodontal ligament stem cells under high glucose conditions.
Zhang YL, An Y, Sun LJ, Qu HL, Li X, He XT, Wu RX, Chen FM, Tian BM, Yin Y
Frontiers in endocrinology 2023;14:1152845
Frontiers in endocrinology 2023;14:1152845
Wogonin induces ferroptosis in pancreatic cancer cells by inhibiting the Nrf2/GPX4 axis.
Liu X, Peng X, Cen S, Yang C, Ma Z, Shi X
Frontiers in pharmacology 2023;14:1129662
Frontiers in pharmacology 2023;14:1129662
Effect of botanical drugs in improving symptoms of hypertensive nephropathy: Analysis of real-world data, retrospective cohort, network, and experimental assessment.
Huan JM, Ma XT, Li SY, Hu DQ, Chen HY, Wang YM, Su XY, Su WG, Wang YF
Frontiers in pharmacology 2023;14:1126972
Frontiers in pharmacology 2023;14:1126972
GPR35 antagonist CID-2745687 attenuates anchorage-independent cell growth by inhibiting YAP/TAZ activity in colorectal cancer cells.
Otkur W, Liu X, Chen H, Li S, Ling T, Lin H, Yang R, Xia T, Qi H, Piao HL
Frontiers in pharmacology 2023;14:1126119
Frontiers in pharmacology 2023;14:1126119
Adjuvant therapy with Huatan Sanjie Granules improves the prognosis of patients with primary liver cancer: a cohort study and the investigation of its mechanism of action based on network pharmacology.
Yuan J, Abdurahman A, Cui N, Hao T, Zou J, Liu L, Wu Y
Frontiers in pharmacology 2023;14:1091177
Frontiers in pharmacology 2023;14:1091177
Vitamin D-VDR (vitamin D receptor) alleviates glucose metabolism reprogramming in lipopolysaccharide-induced acute kidney injury.
Dai Q, Zhang H, Tang S, Wu X, Wang J, Yi B, Liu J, Li Z, Liao Q, Li A, Liu Y, Zhang W
Frontiers in physiology 2023;14:1083643
Frontiers in physiology 2023;14:1083643
CENPH overexpression promotes the progression, cisplatin resistance, and poor prognosis of lung adenocarcinoma via the AKT and ERK/P38 pathways.
Li Q, Huang X, Li QY, Tang Y, Liang LB, Luo Q, Gong M, Song YX, Guo Q, Chen C
American journal of cancer research 2023;13(5):1682-1697
American journal of cancer research 2023;13(5):1682-1697
Metabolic genes, a potential predictor of prognosis and immunogenicity of clear cell renal cell carcinoma.
Ji CJ, Wei XY, Yao LY, Wang YC, Cong R, Song NH
American journal of cancer research 2023;13(4):1387-1406
American journal of cancer research 2023;13(4):1387-1406
MOGS promotes stemness acquisition and invasion via enhancing NOTCH1-glycosylation dependent NOTCH pathway in colorectal cancer.
Zhou S, Huang H, Zheng Z, Zheng K, Xie L
American journal of cancer research 2023;13(12):5996-6010
American journal of cancer research 2023;13(12):5996-6010
Japanese encephalitis virus perturbs PML-nuclear bodies by engaging in interactions with distinct porcine PML isoforms.
Yang S, Liu H, Chen Z, Wang H, Li X, Zhou X, Zhao A
Frontiers in cellular and infection microbiology 2023;13:1239234
Frontiers in cellular and infection microbiology 2023;13:1239234
Crosstalk between septic shock and venous thromboembolism: a bioinformatics and immunoassay analysis.
Li Z, Wang C, Zhang X, Xu X, Wang M, Dong L
Frontiers in cellular and infection microbiology 2023;13:1235269
Frontiers in cellular and infection microbiology 2023;13:1235269
Afatinib combined with anti-PD1 enhances immunotherapy of hepatocellular carcinoma via ERBB2/STAT3/PD-L1 signaling.
Yu C, Zhang X, Wang M, Xu G, Zhao S, Feng Y, Pan C, Yang W, Zhou J, Shang L, Ma Y
Frontiers in oncology 2023;13:1198118
Frontiers in oncology 2023;13:1198118
Identification of a chemoresistance-related prognostic gene signature by comprehensive analysis and experimental validation in pancreatic cancer.
Chen J, Liu Z, Wu Z, Li W, Tan X
Frontiers in oncology 2023;13:1132424
Frontiers in oncology 2023;13:1132424
ITGB1-mediated molecular landscape and cuproptosis phenotype induced the worse prognosis in diffuse gastric cancer.
Zhu X, Chen H, Li H, Ren H, Ye C, Xu K, Liu J, Du F, Zhang Z, Liu Y, Xie X, Wang M, Ma T, Chong W, Shang L, Li L
Frontiers in oncology 2023;13:1115510
Frontiers in oncology 2023;13:1115510
Methylation-mediated silencing of EDN3 promotes cervical cancer proliferation, migration and invasion.
Zhu P, Li X, Liu Y, Xiong J, Yuan D, Chen Y, Luo L, Huang J, Wang B, Nie Q, Wang S, Dang L, Li S, Shu Y, Zhang W, Zhou H, Fan L, Li Q
Frontiers in oncology 2023;13:1010132
Frontiers in oncology 2023;13:1010132
L-Kynurenine participates in cancer immune evasion by downregulating hypoxic signaling in T lymphocytes.
Schlichtner S, Yasinska IM, Klenova E, Abooali M, Lall GS, Berger SM, Ruggiero S, Cholewa D, Milošević M, Gibbs BF, Fasler-Kan E, Sumbayev VV
Oncoimmunology 2023;12(1):2244330
Oncoimmunology 2023;12(1):2244330
MK8617 inhibits M1 macrophage polarization and inflammation via the HIF-1α/GYS1/UDPG/P2Y(14) pathway.
Qian L, Chen XQ, Kong D, Wang G, Cao Y, Xiao Y, Cao JY, Zou C
PeerJ 2023;11:e15591
PeerJ 2023;11:e15591
Downregulation of lncRNA SLC7A11-AS1 decreased the NRF2/SLC7A11 expression and inhibited the progression of colorectal cancer cells.
Wang T, Liang S, Li Y, Wang X, Wang H, Guo J, Li M
PeerJ 2023;11:e15216
PeerJ 2023;11:e15216
FBXO5 acts as a novel prognostic biomarker for patients with cervical cancer.
Jiang S, Zheng J, Cui Z, Li Y, Wu Q, Cai X, Zheng C, Sun Y
Frontiers in cell and developmental biology 2023;11:1200197
Frontiers in cell and developmental biology 2023;11:1200197
KLF2 is a clinical diagnostic and treatment biomarker of breast cancer.
Li YZ, Xie J, Wang RQ, Gao XQ, Liu PJ, Liu J
Frontiers in cell and developmental biology 2023;11:1182123
Frontiers in cell and developmental biology 2023;11:1182123
Effect of stem cell conditional medium-loading adhesive hydrogel on TGF-β1-induced endometrial stromal cell fibrosis.
Zhu Y, Wang T, Bao MJ, Qu XH, Li ZM
Frontiers in bioengineering and biotechnology 2023;11:1168136
Frontiers in bioengineering and biotechnology 2023;11:1168136
Comprehensive Genomic Profiling Identifies FAT1 as a Negative Regulator of EMT, CTCs, and Metastasis of Hepatocellular Carcinoma.
Huang ZL, Zhang PB, Zhang JT, Li F, Li TT, Huang XY
Journal of hepatocellular carcinoma 2023;10:369-382
Journal of hepatocellular carcinoma 2023;10:369-382
Identification of novel candidate targets for suppressing ovarian cancer progression through IL-33/ST2 axis components using the system biology approach.
Reivan Ortiz GG, Ciongradi CI, Chaitanya MVNL, Narayanan J, Mohany M, Al-Rejaie SS, Arias-Gonzáles JL, Sârbu I, Assefi M, Akram SV, Döğüş Y, Bahrami A, Akhavan-Sigari R
Frontiers in molecular biosciences 2023;10:1189527
Frontiers in molecular biosciences 2023;10:1189527
The effect of allyl isothiocyanate on chondrocyte phenotype is matrix stiffness-dependent: Possible involvement of TRPA1 activation.
Che H, Shao Z, Ding J, Gao H, Liu X, Chen H, Cai S, Ge J, Wang C, Wu J, Hao Y
Frontiers in molecular biosciences 2023;10:1112653
Frontiers in molecular biosciences 2023;10:1112653
Single-cell data analysis of malignant epithelial cell heterogeneity in lung adenocarcinoma for patient classification and prognosis prediction.
Ran X, Tong L, Chenghao W, Qi L, Bo P, Jiaying Z, Jun W, Linyou Z
Heliyon 2023 Sep;9(9):e20164
Heliyon 2023 Sep;9(9):e20164
High-expressed PTPN1 promotes tumor proliferation signature in human hepatocellular carcinoma.
Xie L, Qi H, Tian W, Bu S, Wu Z, Wang H
Heliyon 2023 Sep;9(9):e19895
Heliyon 2023 Sep;9(9):e19895
Role of iron in host-microbiota interaction and its effects on intestinal mucosal growth and immune plasticity in a piglet model.
Dong Z, Liu S, Deng Q, Li G, Tang Y, Wu X, Wan D, Yin Y
Science China. Life sciences 2023 Sep;66(9):2086-2098
Science China. Life sciences 2023 Sep;66(9):2086-2098
Targeting ARF1-IQGAP1 interaction to suppress colorectal cancer metastasis and vemurafenib resistance.
Hu HF, Gao GB, He X, Li YY, Li YJ, Li B, Pan Y, Wang Y, He QY
Journal of advanced research 2023 Sep;51:135-147
Journal of advanced research 2023 Sep;51:135-147
TGF-β3 Protects Neurons Against Intermittent Hypoxia-Induced Oxidative Stress and Apoptosis Through Activation of the Nrf-2/KEAP1/HO-1 Pathway via Binding to TGF-βRI.
Huang Y, Liu Z, Wang X, Li Y, Liu L, Li B
Neurochemical research 2023 Sep;48(9):2808-2825
Neurochemical research 2023 Sep;48(9):2808-2825
Antitumor Effects of β-Elemene Through Inducing Autophagy-Mediated Apoptosis in Ewing Sarcoma Family Tumor Cells.
Zhang T, Zhang T, Gao C, Jalal S, Yuan R, Teng H, Li C, Huang L
DNA and cell biology 2023 Sep;42(9):532-540
DNA and cell biology 2023 Sep;42(9):532-540
HIV-1 Infection Promotes Cholesterol Aggregation by Inducing miR-33b-5p to Suppress ABCA1 Expression.
You Q, Qiao J, Peng Q, Li W, Li J, Hu S, Shu Z, Sun B
AIDS research and human retroviruses 2023 Sep;39(9):459-467
AIDS research and human retroviruses 2023 Sep;39(9):459-467
ANRIL regulating the secretion of Muc5ac induced by atmospheric PM(2.5) via NF-κB pathway in Beas-2B cells.
Zhou L, Zhu Y, Zhang T, Zhang R, Liu Y, Li X, Zhao W, Ye J, Ju Y, Ye L
Environmental toxicology 2023 Sep;38(9):2256-2270
Environmental toxicology 2023 Sep;38(9):2256-2270
STAMBPL1 promotes the progression of lung adenocarcinoma by inhibiting DHRS2 expression.
Yang X, Ling L, Li C, Hu T, Zhou C, Chen J, Wang Y, Hu L
Translational oncology 2023 Sep;35:101728
Translational oncology 2023 Sep;35:101728
Apelin-Overexpressing Neural Stem Cells in Conjunction with a Silk Fibroin Nanofiber Scaffold for the Treatment of Traumatic Brain Injury.
Li T, Tang Q, Xu J, Ye X, Chen K, Zhong J, Zhu J, Lu S, Zhu T
Stem cells and development 2023 Sep;32(17-18):539-553
Stem cells and development 2023 Sep;32(17-18):539-553
rhFGF-21 accelerates corneal epithelial wound healing through the attenuation of oxidative stress and inflammatory mediators in diabetic mice.
Li L, Wang H, Pang S, Wang L, Fan Z, Ma C, Yang S, Banda J, Hui Q, Lv F, Fan H, Huang T, Zhang X, Wang X
The Journal of biological chemistry 2023 Sep;299(9):105127
The Journal of biological chemistry 2023 Sep;299(9):105127
Pancreatic stellate cell-derived exosomal tRF-19-PNR8YPJZ promotes proliferation and mobility of pancreatic cancer through AXIN2.
Cao W, Dai S, Ruan W, Long T, Zeng Z, Lei S
Journal of cellular and molecular medicine 2023 Sep;27(17):2533-2546
Journal of cellular and molecular medicine 2023 Sep;27(17):2533-2546
ZBTB7C m6A modification incurred by METTL3 aberration promotes osteosarcoma progression.
An X, Wu W, Yang L, Dong J, Liu B, Guo J, Chen J, Guo B, Cao W, Jiang Q
Translational research : the journal of laboratory and clinical medicine 2023 Sep;259:62-71
Translational research : the journal of laboratory and clinical medicine 2023 Sep;259:62-71
Potential antidepressant-like effects of N-3 polyunsaturated fatty acids through inhibition of endoplasmic reticulum stress.
Tang M, Liu T, Shen Y, Wang L, Xue Y, Zhao T, Xie K, Gong Z, Yin T
Psychopharmacology 2023 Sep;240(9):1877-1889
Psychopharmacology 2023 Sep;240(9):1877-1889
Neuroprotective effect of salidroside on hippocampal neurons in diabetic mice via PI3K/Akt/GSK-3β signaling pathway.
Wang XH, Zuo ZF, Meng L, Yang Q, Lv P, Zhao LP, Wang XB, Wang YF, Huang Y, Fu C, Liu WQ, Liu XZ, Zheng DY
Psychopharmacology 2023 Sep;240(9):1865-1876
Psychopharmacology 2023 Sep;240(9):1865-1876
SIRT3 regulates mitophagy in liver fibrosis through deacetylation of PINK1/NIPSNAP1.
Li R, Wang Z, Wang Y, Sun R, Zou B, Tian X, Liu D, Zhao X, Zhou J, Zhao Y, Yao J
Journal of cellular physiology 2023 Sep;238(9):2090-2102
Journal of cellular physiology 2023 Sep;238(9):2090-2102
ENPP2 inhibitor improves proliferation in AOM/DSS-induced colorectal cancer mice via remodeling the gut barrier function and gut microbiota composition.
Yan J, Duan W, Gao Q, Mao T, Wang M, Duan J, Li J
Pharmacological research 2023 Sep;195:106877
Pharmacological research 2023 Sep;195:106877
Arsenic induced autophagy-dependent apoptosis in hippocampal neurons via AMPK/mTOR signaling pathway.
Chen Y, Liu X, Zhang Q, Wang H, Zhang R, Ge Y, Liang H, Li W, Fan J, Liu H, Lv Z, Dou W, Wang Y, Li X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Sep;179:113954
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Sep;179:113954
Xianlinglianxiafang Inhibited the growth and metastasis of triple-negative breast cancer via activating PPARγ/AMPK signaling pathway.
Yang X, Yang R, Zhang Y, Shi Y, Ma M, Li F, Xie Y, Han X, Liu S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115164
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115164
Caffeoylquinic acids isolated from Lonicera japonica Thunb. as TAK1 inhibitors protects against LPS plus IFN-γ-stimulated inflammation by interacting with KEAP1-regulated NRF2 activation.
Ge L, Jiang Y, Li Y, Xie Q, Miao Y, Wu Z, Zeng X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115038
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115038
Effect of 2-deoxyglucose-mediated inhibition of glycolysis on migration and invasion of HTR-8/SVneo trophoblast cells.
Liang X, Tang S, Song Y, Li D, Zhang L, Wang S, Duan Y, Du H
Journal of reproductive immunology 2023 Sep;159:104123
Journal of reproductive immunology 2023 Sep;159:104123
miR-656-3p inhibits melanomas in vitro and in vivo by inducing senescence via inhibiting LMNB2.
Sun J, Lui K, Pang Q, Xu M, Zhao H, Shao J, Yu Y, Chu X, Liang Y, Xu J, Shen Z
Journal of cancer research and clinical oncology 2023 Sep;149(12):10781-10796
Journal of cancer research and clinical oncology 2023 Sep;149(12):10781-10796
Discovery of potent and selective PI3Kδ inhibitors bearing amino acid fragments.
Lei H, Duan W, Zhang SQ, Feng Y, Ma M, Yuan B, Xin M
Bioorganic chemistry 2023 Sep;138:106594
Bioorganic chemistry 2023 Sep;138:106594
Antitumor synergism between PAK4 silencing and immunogenic phototherapy of engineered extracellular vesicles.
Lu M, Xing H, Shao W, Wu P, Fan Y, He H, Barth S, Zheng A, Liang XJ, Huang Y
Acta pharmaceutica Sinica. B 2023 Sep;13(9):3945-3955
Acta pharmaceutica Sinica. B 2023 Sep;13(9):3945-3955
Milk-derived exosomes carrying siRNA-KEAP1 promote diabetic wound healing by improving oxidative stress.
Xiang X, Chen J, Jiang T, Yan C, Kang Y, Zhang M, Xiang K, Guo J, Jiang G, Wang C, XiangXu, Yang X, Chen Z
Drug delivery and translational research 2023 Sep;13(9):2286-2296
Drug delivery and translational research 2023 Sep;13(9):2286-2296
Elsinochrome A induces cell apoptosis and autophagy in photodynamic therapy.
Yao Y, Pan L, Song W, Yuan Y, Yan S, Yu S, Chen S
Journal of cellular biochemistry 2023 Sep;124(9):1346-1365
Journal of cellular biochemistry 2023 Sep;124(9):1346-1365
Early depletion of M1 macrophages retards the progression of glucocorticoid-associated osteonecrosis of the femoral head.
Cheng Y, Chen H, Duan P, Zhang H, Yu Y, Yu J, Yu Z, Zheng L, Ye X, Pan Z
International immunopharmacology 2023 Sep;122:110639
International immunopharmacology 2023 Sep;122:110639
FTZ polysaccharides ameliorate kidney injury in diabetic mice by regulating gut-kidney axis.
Lan T, Tang T, Li Y, Duan Y, Yuan Q, Liu W, Ren Y, Li N, Liu X, Zhang Y, Li X, Jin G, Wang S, Guo J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154935
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154935
LINC00346 regulates NLRP1-mediated pyroptosis and autophagy via binding to microRNA-637 in vascular endothelium injury.
Ge JY, Yan XJ, Yang J, Jin H, Sun ZK, Guo JL, Zhu Y, Wang FF
Cellular signalling 2023 Sep;109:110740
Cellular signalling 2023 Sep;109:110740
Suppression of PGE2/EP2 signaling alleviates Hirschsprung disease by upregulating p38 mitogen-activated protein kinase activity.
Wang J, Zhi Z, Ding J, Jia N, Hu Y, Cai J, Li H, Tang J, Tang W, Mao X
Journal of molecular medicine (Berlin, Germany) 2023 Sep;101(9):1125-1139
Journal of molecular medicine (Berlin, Germany) 2023 Sep;101(9):1125-1139
FTO-mediated m6A modification alleviates autoimmune uveitis by regulating microglia phenotypes via the GPC4/TLR4/NF-κB signaling axis.
He S, Li W, Wang G, Wang X, Fan W, Zhang Z, Li N, Hou S
Genes & diseases 2023 Sep;10(5):2179-2193
Genes & diseases 2023 Sep;10(5):2179-2193
Targeting Squalene Epoxidase Confers Metabolic Vulnerability and Overcomes Chemoresistance in HNSCC.
Zhao X, Guo B, Sun W, Yu J, Cui L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(27):e2206878
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(27):e2206878
NDUFC2 deficiency exacerbates endothelial mesenchymal transformation during ischemia-reperfusion via NLRP3.
Chen J, Liu X, Bi R, Liu P, Gong W
Neuroreport 2023 Sep 6;34(13):670-676
Neuroreport 2023 Sep 6;34(13):670-676
The panda-derived Lactiplantibacillus plantarum BSG201683 improves LPS-induced intestinal inflammation and epithelial barrier disruption in vitro.
Zhou Y, Duan L, Zeng Y, Song X, Pan K, Niu L, Pu Y, Li J, Khalique A, Fang J, Jing B, Zeng D, Shen B, Ni X
BMC microbiology 2023 Sep 6;23(1):249
BMC microbiology 2023 Sep 6;23(1):249
Bioengineered "Molecular Glue"-Mediated Tumor-Specific Cascade Nanoreactors with Self-Destruction Ability for Enhanced Precise Starvation/Chemosynergistic Tumor Therapy.
Zhang Q, Xuan Q, Wang C, Shi C, Wang X, Ma T, Zhang W, Li H, Wang P, Chen C
ACS applied materials & interfaces 2023 Sep 6;15(35):41271-41286
ACS applied materials & interfaces 2023 Sep 6;15(35):41271-41286
Oridonin inhibits the occurrence and development of colorectal cancer by reversing the Warburg effect via reducing PKM2 dimer formation and preventing its entry into the nucleus.
Chen F, Liao J, Wu P, Cheng L, Ma Y, Zhang L, Leng X, Zhu X, Liu Z, Xie F
European journal of pharmacology 2023 Sep 5;954:175856
European journal of pharmacology 2023 Sep 5;954:175856
Site-specific Atg13 methylation-mediated autophagy regulates epithelial inflammation in PM2.5-induced pulmonary fibrosis.
Ning J, Pei Z, Wang M, Hu H, Chen M, Liu Q, Wu M, Yang P, Geng Z, Zheng J, Du Z, Hu W, Wang Q, Pang Y, Bao L, Niu Y, Leng S, Zhang R
Journal of hazardous materials 2023 Sep 5;457:131791
Journal of hazardous materials 2023 Sep 5;457:131791
Comprehensive analysis and experimental validation reveal elevated CLCN4 is a promising biomarker in endometrial cancer.
Wang C, Li J, Liu W, Li S, Zhang Y, Jin Y, Cui J
Aging 2023 Sep 5;15(17):8744-8769
Aging 2023 Sep 5;15(17):8744-8769
The effects of Shikonin on the hypertrophic scar of rabbit ears via the TLR4/NF-κB signaling pathway.
Liu C, Zhang H, Cui X, Wang S, Zhou Q
Cellular and molecular biology (Noisy-le-Grand, France) 2023 Sep 30;69(9):161-166
Cellular and molecular biology (Noisy-le-Grand, France) 2023 Sep 30;69(9):161-166
Oat β-D-glucan ameliorates type II diabetes through TLR4/PI3K/AKT mediated metabolic axis.
Guo H, Wu H, Hou Y, Hu P, Du J, Cao L, Yang R, Dong X, Li Z
International journal of biological macromolecules 2023 Sep 30;249:126039
International journal of biological macromolecules 2023 Sep 30;249:126039
A phellinus igniarius polysaccharide/chitosan-arginine hydrogel for promoting diabetic wound healing.
Zhang L, Yang J, Liu W, Ding Q, Sun S, Zhang S, Wang N, Wang Y, Xi S, Liu C, Ding C, Li C
International journal of biological macromolecules 2023 Sep 30;249:126014
International journal of biological macromolecules 2023 Sep 30;249:126014
Selective Impact of Selenium Compounds on Two Cytokine Storm Players.
Sinha I, Zhu J, Sinha R
Journal of personalized medicine 2023 Sep 30;13(10)
Journal of personalized medicine 2023 Sep 30;13(10)
Omentin-1 induces mechanically activated fibroblasts lipogenic differentiation through pkm2/yap/pparγ pathway to promote lung fibrosis resolution.
Zhang Y, Fu J, Li C, Chang Y, Li X, Cheng H, Qiu Y, Shao M, Han Y, Feng D, Yue S, Sun Z, Luo Z, Zhou Y
Cellular and molecular life sciences : CMLS 2023 Sep 28;80(10):308
Cellular and molecular life sciences : CMLS 2023 Sep 28;80(10):308
Type I/type III IFN and related factors regulate JEV infection and BBB endothelial integrity.
Zhang YG, Zhang HX, Chen HW, Lv P, Su J, Chen YR, Fu ZF, Cui M
Journal of neuroinflammation 2023 Sep 27;20(1):216
Journal of neuroinflammation 2023 Sep 27;20(1):216
Mechanical stiffness promotes skin fibrosis through Piezo1-mediated arginine and proline metabolism.
He J, Fang B, Shan S, Li Q
Cell death discovery 2023 Sep 26;9(1):354
Cell death discovery 2023 Sep 26;9(1):354
STING signaling promotes NK cell antitumor immunity and maintains a reservoir of TCF-1(+) NK cells.
Lu L, Yang C, Zhou X, Wu L, Hong X, Li W, Wang X, Yang Y, Cao D, Zhang A, Di W, Deng L
Cell reports 2023 Sep 26;42(9):113108
Cell reports 2023 Sep 26;42(9):113108
Fatty acid synthesis and oxidation regulate human endoderm differentiation by mediating SMAD3 nuclear localization via acetylation.
Yi Y, Lan X, Li Y, Yan C, Lv J, Zhang T, Jiang W
Developmental cell 2023 Sep 25;58(18):1670-1687.e4
Developmental cell 2023 Sep 25;58(18):1670-1687.e4
Metformin induces ferroptosis through the Nrf2/HO-1 signaling in lung cancer.
Deng C, Xiong L, Chen Y, Wu K, Wu J
BMC pulmonary medicine 2023 Sep 25;23(1):360
BMC pulmonary medicine 2023 Sep 25;23(1):360
Activation of CTNNB1 by deubiquitinase UCHL3-mediated stabilization facilitates bladder cancer progression.
Liu T, Fan MQ, Xie XX, Shu QP, Du XH, Qi LZ, Zhang XD, Zhang MH, Shan G, Du RL, Li SZ
Journal of translational medicine 2023 Sep 22;21(1):656
Journal of translational medicine 2023 Sep 22;21(1):656
Human umbilical cord-derived mesenchymal stem cells ameliorate perioperative neurocognitive disorder by inhibiting inflammatory responses and activating BDNF/TrkB/CREB signaling pathway in aged mice.
Wei P, Jia M, Kong X, Lyu W, Feng H, Sun X, Li J, Yang JJ
Stem cell research & therapy 2023 Sep 21;14(1):263
Stem cell research & therapy 2023 Sep 21;14(1):263
Bisphenol P and bisphenol M promote triple-negative breast cancer metastasis through activation of AKT pathways.
Liu J, Wang H, Hou X, Fan L, Yang F, Dai Y, Deng Y, Fu Z, Shu X, Sun B, Liu Y
The Science of the total environment 2023 Sep 20;892:164748
The Science of the total environment 2023 Sep 20;892:164748
[Isodopharicin C inhibits NLRP3 inflammasome activation and alleviates septic shock in mice].
Cao H, Zhang W, Li M, Yang Y, Li Y
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Sep 20;43(9):1476-1484
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Sep 20;43(9):1476-1484
FGF2 Rescued Cisplatin-Injured Granulosa Cells through the NRF2-Autophagy Pathway.
Wang L, Cheng F, Pan R, Cui Z, She J, Zhang Y, Yang X
International journal of molecular sciences 2023 Sep 18;24(18)
International journal of molecular sciences 2023 Sep 18;24(18)
VprBP/DCAF1 Triggers Melanomagenic Gene Silencing through Histone H2A Phosphorylation.
Shin Y, Kim S, Liang G, Ulmer TS, An W
Biomedicines 2023 Sep 17;11(9)
Biomedicines 2023 Sep 17;11(9)
3,5,6-Trichloro-2-pyridinol confirms ototoxicity in mouse cochlear organotypic cultures and induces cytotoxicity in HEI-OC1 cells.
Huang M, Zou M, Mao S, Xu W, Hong Y, Wang H, Gui F, Yang L, Lian F, Chen R
Toxicology and applied pharmacology 2023 Sep 15;475:116612
Toxicology and applied pharmacology 2023 Sep 15;475:116612
Mitochondrial miR-12294-5p regulated copper-induced mitochondrial oxidative stress and mitochondrial quality control imbalance by targeted inhibition of CISD1 in chicken livers.
Zhong G, Li Y, Li L, Huo Y, Zhang W, Li T, Ma F, Liao J, Li Y, Zhang H, Guo J, Pan J, Yu W, Hu L, Tang Z
Journal of hazardous materials 2023 Sep 15;458:131908
Journal of hazardous materials 2023 Sep 15;458:131908
Systems pharmacology reveals the mechanism of Astragaloside IV in improving immune activity on cyclophosphamide-induced immunosuppressed mice.
Yao J, Liu J, He Y, Liu L, Xu Z, Lin X, Liu N, Kai G
Journal of ethnopharmacology 2023 Sep 15;313:116533
Journal of ethnopharmacology 2023 Sep 15;313:116533
FDX1 regulates leydig cell ferroptosis mediates PM(2.5)-induced testicular dysfunction of mice.
Li L, Pei Z, Wu R, Zhang Y, Pang Y, Hu H, Hu W, Geng Z, Feng T, Niu Y, Hao G, Zhang R
Ecotoxicology and environmental safety 2023 Sep 15;263:115309
Ecotoxicology and environmental safety 2023 Sep 15;263:115309
Noradrenaline transporter PET reflects neurotoxin-induced noradrenaline level decrease in the rat hippocampus.
Sakai T, Hattori S, Ogata A, Yamada T, Abe J, Ikenuma H, Ichise M, Suzuki M, Ito K, Kato T, Kimura Y
EJNMMI research 2023 Sep 15;13(1):82
EJNMMI research 2023 Sep 15;13(1):82
Sea Cucumber Peptide Alleviates Ulcerative Colitis Induced by Dextran Sulfate Sodium by Alleviating Gut Microbiota Imbalance and Regulating miR-155/SOCS1 Axis in Mice.
Mao J, Zhao Y, Wang L, Wu T, Jin Y, Meng J, Zhang M
Foods (Basel, Switzerland) 2023 Sep 15;12(18)
Foods (Basel, Switzerland) 2023 Sep 15;12(18)
MicroRNA miR-223 modulates NLRP3 and Keap1, mitigating lipopolysaccharide-induced inflammation and oxidative stress in bovine mammary epithelial cells and murine mammary glands.
Zhou M, Barkema HW, Gao J, Yang J, Wang Y, Kastelic JP, Khan S, Liu G, Han B
Veterinary research 2023 Sep 14;54(1):78
Veterinary research 2023 Sep 14;54(1):78
Inhibition of TLR4 Signaling by Isorhapontigenin Targeting of the AHR Alleviates Cerebral Ischemia/Reperfusion Injury.
Liu J, Mu D, Xu J, Liu Y, Zhang G, Tang Y, Wang D, Wang F, Liang D, Hou Y
Journal of agricultural and food chemistry 2023 Sep 13;71(36):13270-13283
Journal of agricultural and food chemistry 2023 Sep 13;71(36):13270-13283
Celastrol attenuates streptozotocin-induced diabetic cardiomyopathy in mice by inhibiting the ACE / Ang II / AGTR1 signaling pathway.
Zhao X, Huang B, Zhang J, Xiang W, Zhu N
Diabetology & metabolic syndrome 2023 Sep 12;15(1):186
Diabetology & metabolic syndrome 2023 Sep 12;15(1):186
FUNDC1 modulates mitochondrial defects and pancreatic β-cell dysfunction under lipotoxicity.
Tong B, Zhang Z, Li X, Liu J, Wang H, Song L, Feng J, Dai Z, Xu Y
Biochemical and biophysical research communications 2023 Sep 10;672:54-64
Biochemical and biophysical research communications 2023 Sep 10;672:54-64
FAT4 overexpression promotes antitumor immunity by regulating the β-catenin/STT3/PD-L1 axis in cervical cancer.
Wang D, Wu S, He J, Sun L, Zhu H, Zhang Y, Liu S, Duan X, Wang Y, Xu T
Journal of experimental & clinical cancer research : CR 2023 Sep 1;42(1):222
Journal of experimental & clinical cancer research : CR 2023 Sep 1;42(1):222
Loganin reduces diabetic kidney injury by inhibiting the activation of NLRP3 inflammasome-mediated pyroptosis.
Kong X, Zhao Y, Wang X, Yu Y, Meng Y, Yan G, Yu M, Jiang L, Song W, Wang B, Wang X
Chemico-biological interactions 2023 Sep 1;382:110640
Chemico-biological interactions 2023 Sep 1;382:110640
Shikonin suppresses small cell lung cancer growth via inducing ATF3-mediated ferroptosis to promote ROS accumulation.
Qian X, Zhu L, Xu M, Liu H, Yu X, Shao Q, Qin J
Chemico-biological interactions 2023 Sep 1;382:110588
Chemico-biological interactions 2023 Sep 1;382:110588
Chimeric antigen receptor macrophages activated through TLR4 or IFN-γ receptors suppress breast cancer growth by targeting VEGFR2.
Duan Z, Li Z, Wang Z, Chen C, Luo Y
Cancer immunology, immunotherapy : CII 2023 Oct;72(10):3243-3257
Cancer immunology, immunotherapy : CII 2023 Oct;72(10):3243-3257
Ferroptosis triggered by STAT1- IRF1-ACSL4 pathway was involved in radiation-induced intestinal injury.
Kong P, Yang M, Wang Y, Yu KN, Wu L, Han W
Redox biology 2023 Oct;66:102857
Redox biology 2023 Oct;66:102857
Lnc‑RGS5 sponges miR‑542‑5p to promote FoxM1/VEGFA signaling and breast cancer cell proliferation.
Song J, Tang Y, Song F
International journal of oncology 2023 Oct;63(4)
International journal of oncology 2023 Oct;63(4)
Constitutively activated AMPKα1 protects against skeletal aging in mice by promoting bone-derived IGF-1 secretion.
Yang Y, Yuan K, Liu Y, Wang Q, Lin Y, Yang S, Huang K, Kan T, Zhang Y, Xu M, Yu Z, Fan Q, Wang Y, Li H, Tang T
Cell proliferation 2023 Oct;56(10):e13476
Cell proliferation 2023 Oct;56(10):e13476
Edaravone Dexborneol Alleviates Neuroinflammation by Reducing Neuroglial Cell Proliferation and Suppresses Neuronal Apoptosis/Autophagy in Vascular Dementia Rats.
Zhang J, Xiao Y, Liu H, Xu L, Guo X, Gao Y, Li M, Xu J, Qi Q, Lv P
Neurochemical research 2023 Oct;48(10):3113-3128
Neurochemical research 2023 Oct;48(10):3113-3128
Intrathecal Injection of Botulinum Toxin Type A has an Analgesic Effect in Male Rats CCI Model by Inhibiting the Activation of Spinal P2X4R.
Zhou WM, Lei ZY, Shi YQ, Gong CY, Kai Z, Wei N, Wang LN, Zhang CJ, Zhang HH
Neurochemical research 2023 Oct;48(10):3099-3112
Neurochemical research 2023 Oct;48(10):3099-3112
The PRMT5 inhibitor C9 mitigates hypoxia-induced carboplatin resistance in lung cancer by inducing autophagy.
Fan J, Li H, Ruan Q, Zhu X, Jing P, Gu Z
Cell biology international 2023 Oct;47(10):1702-1715
Cell biology international 2023 Oct;47(10):1702-1715
Bavachinin Ameliorates Rheumatoid Arthritis Inflammation via PPARG/PI3K/AKT Signaling Pathway.
Deng H, Jiang J, Shu J, Huang M, Zhang QL, Wu LJ, Sun WK
Inflammation 2023 Oct;46(5):1981-1996
Inflammation 2023 Oct;46(5):1981-1996
Integrated Machine Learning and Bioinformatic Analyses Constructed a Network Between Mitochondrial Dysfunction and Immune Microenvironment of Periodontitis.
Chen H, Peng L, Wang Z, He Y, Zhang X
Inflammation 2023 Oct;46(5):1932-1951
Inflammation 2023 Oct;46(5):1932-1951
Decreasing REDD1 expression protects against high glucose-induced apoptosis, oxidative stress and inflammatory injury in podocytes through regulation of the AKT/GSK-3β/Nrf2 pathway.
Wang X, Yang J, Wang W, Li Y, Yang Y
Immunopharmacology and immunotoxicology 2023 Oct;45(5):527-538
Immunopharmacology and immunotoxicology 2023 Oct;45(5):527-538
Spinosin protects Neuro-2a/APP695 cells from oxidative stress damage by inactivating p38.
Xiaoying Z, Ruixuan W, Yiqing W, Fanxing XU, Tingxu Y, Bo WU, Ming Z, Ying J
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2023 Oct;43(5):868-875
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2023 Oct;43(5):868-875
Brexpiprazole suppresses cell proliferation and de novo lipogenesis through AMPK/SREBP1 pathway in colorectal cancer.
Li T, Liu X, Long X, Li Y, Xiang J, Lv Y, Zhao X, Shi S, Chen W
Environmental toxicology 2023 Oct;38(10):2352-2360
Environmental toxicology 2023 Oct;38(10):2352-2360
PDK4 facilitates fibroblast functions and diabetic wound healing through regulation of HIF-1α protein stability and gene expression.
Ma Z, Mo R, Yang P, Ding Y, Zhang H, Dong Z, Chen Y, Tan Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Oct;37(10):e23215
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Oct;37(10):e23215
Placental DNA methylation analysis of selective fetal growth restriction in monochorionic twins reveals aberrant methylated CYP11A1 gene for fetal growth restriction.
Shi D, Zhou X, Cai L, Wei X, Zhang L, Sun Q, Zhou F, Sun L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Oct;37(10):e23207
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Oct;37(10):e23207
Protective effect of evolocumab on Müller cells in the rat retina under hyperglycaemic and hypoxic conditions.
Zhou Q, Tang H, Li S
Journal of diabetes and its complications 2023 Oct;37(10):108593
Journal of diabetes and its complications 2023 Oct;37(10):108593
PM2.5 mediates mouse testis Sertoli TM4 cell damage by reducing cellular NAD().
Xu P, Ren T, Yang Y
Toxicology mechanisms and methods 2023 Oct;33(8):636-645
Toxicology mechanisms and methods 2023 Oct;33(8):636-645
6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio) Hexanol Inhibits Proliferation and Induces Apoptosis of Endometriosis by Regulating Glutathione S-Transferase Mu Class 4.
Liu W, Cheng L, Du Y, Liu X, Ma J, Yan L
Reproductive sciences (Thousand Oaks, Calif.) 2023 Oct;30(10):2945-2961
Reproductive sciences (Thousand Oaks, Calif.) 2023 Oct;30(10):2945-2961
Metabolic reprogramming contributes to radioprotection by protein kinase Cδ.
Ohm AM, Affandi T, Reisz JA, Caino MC, D'Alessandro A, Reyland ME
The Journal of biological chemistry 2023 Oct;299(10):105186
The Journal of biological chemistry 2023 Oct;299(10):105186
Oocytes orchestrate protein prenylation for mitochondrial function through selective inactivation of cholesterol biosynthesis in murine species.
Sang Y, Yang Q, Guo Y, Liu X, Shen D, Jiang C, Wang X, Li K, Wang H, Yang C, Ding L, Sun H, Guo X, Li C
The Journal of biological chemistry 2023 Oct;299(10):105183
The Journal of biological chemistry 2023 Oct;299(10):105183
Resveratrol improves palmitic acid‑induced insulin resistance via the DDIT4/mTOR pathway in C2C12 cells.
Pan X, Liu C, Wang X, Zhao M, Zhang Z, Zhang X, Wang C, Song G
Molecular medicine reports 2023 Oct;28(4)
Molecular medicine reports 2023 Oct;28(4)
Hsa_circ_0001535 inhibits the proliferation and migration of ovarian cancer by sponging miR-593-3p, upregulating PTEN expression.
Han Y, Zheng Y, You J, Han Y, Lu X, Wang X, Shi C, Zhu W
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 Oct;25(10):2901-2910
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 Oct;25(10):2901-2910
SARS-COV-2 spike protein promotes RPE cell senescence via the ROS/P53/P21 pathway.
Zhang Y, Peng X, Xue M, Liu J, Shang G, Jiang M, Chen D, Liu B, Wang Y, Jia X, Xu J, Zhang F, Hu Y
Biogerontology 2023 Oct;24(5):813-827
Biogerontology 2023 Oct;24(5):813-827
cFLIP(S) regulates alternative NLRP3 inflammasome activation in human monocytes.
Gao Y, Yu S, Chen M, Wang X, Pan L, Wei B, Meng G
Cellular & molecular immunology 2023 Oct;20(10):1203-1215
Cellular & molecular immunology 2023 Oct;20(10):1203-1215
Proliferation-associated 2G4 P48 is stabilized by malignant T-cell amplified sequence 1 and promotes the proliferation of head and neck squamous cell carcinoma.
Sun L, Xing G, Wang W, Ma X, Bu X
Journal of dental sciences 2023 Oct;18(4):1588-1597
Journal of dental sciences 2023 Oct;18(4):1588-1597
The circular RNA Rap1b promotes Hoxa5 transcription by recruiting Kat7 and leading to increased Fam3a expression, which inhibits neuronal apoptosis in acute ischemic stroke.
Zhang FF, Zhang L, Zhao L, Lu Y, Dong X, Liu YQ, Li Y, Guo S, Zheng SY, Xiao Y, Jiang YZ
Neural regeneration research 2023 Oct;18(10):2237-2245
Neural regeneration research 2023 Oct;18(10):2237-2245
High frequency of alternative splicing variants of the oncogene Focal Adhesion Kinase in neuroendocrine tumors of the pancreas and breast.
Xie D, Wang Z, Sun B, Qu L, Zeng M, Feng L, Guo M, Wang G, Hao J, Zhou G
Frontiers of medicine 2023 Oct;17(5):907-923
Frontiers of medicine 2023 Oct;17(5):907-923
The protective role of shenqi compound in type 2 diabetes: A comprehensive investigation of pancreatic β-cell function and mass.
Yang C, Liu H, Xie Z, Yang Q, Du L, Xie C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115287
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115287
Neuroprotection of NSC Therapy is Superior to Glibenclamide in Cardiac Arrest-Induced Brain Injury via Neuroinflammation Regulation.
Wang Z, Zhang S, Du J, Lachance BB, Chen S, Polster BM, Jia X
Translational stroke research 2023 Oct;14(5):723-739
Translational stroke research 2023 Oct;14(5):723-739
Discovery of small molecule β-catenin suppressors that enhance immunotherapy.
Feng X, Ge J, Fu H, Miao L, Zhao F, Wang J, Sun Y, Li Y, Li Y
Bioorganic chemistry 2023 Oct;139:106754
Bioorganic chemistry 2023 Oct;139:106754
Transgenic mice producing the trans 10, cis 12-conjugated linoleic acid present reduced adiposity and increased thermogenesis and fibroblast growth factor 21 (FGF21).
Rao Y, Li SL, Li MJ, Wang BZ, Wang YY, Liang LW, Yu S, Liu ZP, Cui S, Gou KM
The Journal of nutritional biochemistry 2023 Oct;120:109419
The Journal of nutritional biochemistry 2023 Oct;120:109419
Pterostilbene participates in TLR4- mediated inflammatory response and autophagy-dependent Aβ(1-42) endocytosis in Alzheimer's disease.
Xu J, Liu J, Li Q, Li G, Zhang G, Mi Y, Zhao T, Mu D, Wang D, Zeng K, Hou Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155011
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155011
TCFL5 knockdown sensitizes DLBCL to doxorubicin treatment via regulation of GPX4.
Lu X, Zhang Q, Xie Y
Cellular signalling 2023 Oct;110:110831
Cellular signalling 2023 Oct;110:110831
LGR4 promotes tumorigenesis by activating TGF-β1/Smad signaling pathway in multiple myeloma.
Yi Z, Ma T, Liu J, Tie W, Li Y, Bai J, Li L, Zhang L
Cellular signalling 2023 Oct;110:110814
Cellular signalling 2023 Oct;110:110814
Mechanism of the HIF-1α/VEGF/VEGFR-2 pathway in the proliferation and apoptosis of human haemangioma endothelial cells.
Zhang W, Sun L, Gao H, Wang S
International journal of experimental pathology 2023 Oct;104(5):258-268
International journal of experimental pathology 2023 Oct;104(5):258-268
The polyA tail facilitates splicing of last introns with weak 3' splice sites via PABPN1.
Huang L, Li G, Du C, Jia Y, Yang J, Fan W, Xu YZ, Cheng H, Zhou Y
EMBO reports 2023 Oct 9;24(10):e57128
EMBO reports 2023 Oct 9;24(10):e57128
The GLI2/CDH6 axis enhances migration, invasion and mitochondrial fission of stomach adenocarcinoma cells.
Liu GY, Wang H, Ran R, Wang YC, Li Y
Biochemical and biophysical research communications 2023 Oct 8;676:182-189
Biochemical and biophysical research communications 2023 Oct 8;676:182-189
Clinical significance and immune infiltration analyses of a novel coagulation-related signature in ovarian cancer.
Yang J, Wang C, Zhang Y, Cheng S, Wu M, Gu S, Xu S, Wu Y, Sheng J, Voon DC, Wang Y
Cancer cell international 2023 Oct 6;23(1):232
Cancer cell international 2023 Oct 6;23(1):232
A network pharmacology approach to investigate dehydrocostus lactone inhibits the proliferation and epithelial-mesenchymal transition of human gastric cancer cells via regulating the PI3K/Akt and extracellular signal-regulated kinases/mitogen-activated protein kinase signalling pathways.
Wan M, Dai J, Gan A, Wang J, Lin F, Zhang X, Lv X, Wu B, Yan T, Jia Y
The Journal of pharmacy and pharmacology 2023 Oct 5;75(10):1344-1356
The Journal of pharmacy and pharmacology 2023 Oct 5;75(10):1344-1356
Discovery of tetrahydroisoquinolineindole derivatives as first dual PRMT5 inhibitors/hnRNP E1 upregulators: Design, synthesis and biological evaluation.
Chu WH, Yang N, Zhang JH, Li Y, Song JL, Deng ZP, Meng N, Zhang J, Zhu KK, Jiang CS
European journal of medicinal chemistry 2023 Oct 5;258:115625
European journal of medicinal chemistry 2023 Oct 5;258:115625
GSDMD promotes neutrophil extracellular traps via mtDNA-cGAS-STING pathway during lung ischemia/reperfusion.
Zhao C, Liang F, Ye M, Wu S, Qin Y, Zhao L, Zhang L, He J, Cen L, Lin F
Cell death discovery 2023 Oct 4;9(1):368
Cell death discovery 2023 Oct 4;9(1):368
Broad-spectrum vaccine via combined immunization routes triggers potent immunity to SARS-CoV-2 and its variants.
Xing M, Wang Y, Wang X, Liu J, Dai W, Hu G, He F, Zhao Q, Li Y, Sun L, Wang Y, Du S, Dong Z, Pang C, Hu Z, Zhang X, Xu J, Cai Q, Zhou D
Journal of virology 2023 Oct 31;97(10):e0072423
Journal of virology 2023 Oct 31;97(10):e0072423
Primary cilia control oligodendrocyte precursor cell proliferation in white matter injury via Hedgehog-independent CREB signaling.
Hoi KK, Xia W, Wei MM, Ulloa Navas MJ, Garcia Verdugo JM, Nachury MV, Reiter JF, Fancy SPJ
Cell reports 2023 Oct 31;42(10):113272
Cell reports 2023 Oct 31;42(10):113272
Virus-induced lncRNA-BTX allows viral replication by regulating intracellular translocation of DHX9 and ILF3 to induce innate escape.
Cao Y, Wu J, Hu Y, Chai Y, Song J, Duan J, Zhang S, Xu X
Cell reports 2023 Oct 31;42(10):113262
Cell reports 2023 Oct 31;42(10):113262
NLRP3 Inflammasome Activates Endothelial-to-Mesenchymal Transition via Focal Adhesion Kinase Pathway in Bleomycin-Induced Pulmonary Fibrosis.
Chen WC, Yu WK, Su VY, Hsu HS, Yang KY
International journal of molecular sciences 2023 Oct 31;24(21)
International journal of molecular sciences 2023 Oct 31;24(21)
Activation of NLRP3 Inflammasome via Drp1 Overexpression in Kupffer Cells Aggravates Ischemia-reperfusion Injury in Hepatic Steatosis.
Zhang L, Wang M, An R, Dai J, Liu S, Chen M, Ding H
Journal of clinical and translational hepatology 2023 Oct 28;11(5):1069-1078
Journal of clinical and translational hepatology 2023 Oct 28;11(5):1069-1078
TiO(2) nanoparticles promote tumor metastasis by eliciting pro-metastatic extracellular vesicles.
Mu X, Hu K, Wei A, Bai J, Feng L, Jiang J
Journal of nanobiotechnology 2023 Oct 27;21(1):392
Journal of nanobiotechnology 2023 Oct 27;21(1):392
Metabolism-associated molecular classification of cervical cancer.
Zhao M, Zhang X, Huan Q, Dong M
BMC women's health 2023 Oct 26;23(1):555
BMC women's health 2023 Oct 26;23(1):555
Circular RNA P4HB promotes glycolysis and tumor progression by binding with PKM2 in lung adenocarcinoma.
Li H, Guo H, Huang Q, Wang S, Li X, Qiu M
Respiratory research 2023 Oct 25;24(1):252
Respiratory research 2023 Oct 25;24(1):252
Identification of Novel Targeting Sites of Calcineurin and CaMKII in Human Ca(V)3.2 T-Type Calcium Channel.
Chang YW, Chen YC, Chen CC
Biomedicines 2023 Oct 25;11(11)
Biomedicines 2023 Oct 25;11(11)
The Dual-Mode Transition of Myofibroblasts Derived from Hepatic Stellate Cells in Liver Fibrosis.
Yan M, Xie Y, Yao J, Li X
International journal of molecular sciences 2023 Oct 23;24(20)
International journal of molecular sciences 2023 Oct 23;24(20)
Acteoside protects podocyte against apoptosis through regulating AKT/GSK-3β signaling pathway in db/db mice.
Li X, Liu Z, He Z, Wang X, Li R, Wang J, Ma G, Zhang P, Ma C
BMC endocrine disorders 2023 Oct 23;23(1):230
BMC endocrine disorders 2023 Oct 23;23(1):230
Global lactylome reveals lactylation-dependent mechanisms underlying T(H)17 differentiation in experimental autoimmune uveitis.
Fan W, Wang X, Zeng S, Li N, Wang G, Li R, He S, Li W, Huang J, Li X, Liu J, Hou S
Science advances 2023 Oct 20;9(42):eadh4655
Science advances 2023 Oct 20;9(42):eadh4655
TCAF2 is associated with the immune microenvironment, promotes pathogenesis, and impairs prognosis in glioma.
Li Y, Li J, Chen H, Lu B, Lu F, Chen H, Liu H, Qian C
Gene 2023 Oct 20;883:147667
Gene 2023 Oct 20;883:147667
Butyrate prevents visceral adipose tissue inflammation and metabolic alterations in a Friedreich's ataxia mouse model.
Turchi R, Sciarretta F, Ceci V, Tiberi M, Audano M, Pedretti S, Panebianco C, Nesci V, Pazienza V, Ferri A, Carotti S, Chiurchiù V, Mitro N, Lettieri-Barbato D, Aquilano K
iScience 2023 Oct 20;26(10):107713
iScience 2023 Oct 20;26(10):107713
ER-associated degradation in cystinosis pathogenesis and the prospects of precision medicine.
Venkatarangan V, Zhang W, Yang X, Thoene J, Hahn SH, Li M
The Journal of clinical investigation 2023 Oct 2;133(19)
The Journal of clinical investigation 2023 Oct 2;133(19)
The effect of acupuncture on lateral habenular nucleus and intestinal microflora in depression model rats.
Chen W, Chen Y, Aslam MS, Shen J, Tong T, Yan S, Cheng W, Huang Z, Li J, Liu S, Li J, Zeng J, Li M, You Z, Meng X
Behavioural brain research 2023 Oct 18;455:114627
Behavioural brain research 2023 Oct 18;455:114627
FDCA Attenuates Neuroinflammation and Brain Injury after Cerebral Ischemic Stroke.
Guan X, Wei D, Liang Z, Xie L, Wang Y, Huang Z, Wu J, Pang T
ACS chemical neuroscience 2023 Oct 18;14(20):3839-3854
ACS chemical neuroscience 2023 Oct 18;14(20):3839-3854
A Study of Gentianae Radix et Rhizoma Class Differences Based on Chemical Composition and Core Efficacy.
Kou B, Jiang Y, Chen Y, Yang J, Sun J, Yan Y, Weng L, Xiao C
Molecules (Basel, Switzerland) 2023 Oct 17;28(20)
Molecules (Basel, Switzerland) 2023 Oct 17;28(20)
The mitochondrial fusion-associated protein MFN2 can be used as a novel prognostic molecule for clear cell renal cell carcinoma.
Zhang B, Han D, Yang L, He Y, Yang S, Wang H, Zhang X, Du Y, Xiong W, Ha H, Shang P
BMC cancer 2023 Oct 16;23(1):986
BMC cancer 2023 Oct 16;23(1):986
Integrated single-cell and bulk RNA sequencing in pancreatic cancer identifies disulfidptosis-associated molecular subtypes and prognostic signature.
Wu Y, Shang J, Ruan Q, Tan X
Scientific reports 2023 Oct 16;13(1):17577
Scientific reports 2023 Oct 16;13(1):17577
Afzelin protects against doxorubicin-induced cardiotoxicity by promoting the AMPKα/SIRT1 signaling pathway.
Sun Y, Guo D, Yue S, Zhou M, Wang D, Chen F, Wang L
Toxicology and applied pharmacology 2023 Oct 15;477:116687
Toxicology and applied pharmacology 2023 Oct 15;477:116687
Dendrobium officinale polysaccharide Converts M2 into M1 Subtype Macrophage Polarization via the STAT6/PPAR-r and JAGGED1/NOTCH1 Signaling Pathways to Inhibit Gastric Cancer.
Zhao Y, Lu X, Huang H, Yao Y, Liu H, Sun Y
Molecules (Basel, Switzerland) 2023 Oct 12;28(20)
Molecules (Basel, Switzerland) 2023 Oct 12;28(20)
Fermented cordyceps powder alleviates silica-induced pulmonary inflammation and fibrosis in rats by regulating the Th immune response.
Pu S, Yang Z, Zhang X, Li M, Han N, Yang X, He J, Yu G, Meng X, Jia Q, Shao H
Chinese medicine 2023 Oct 12;18(1):131
Chinese medicine 2023 Oct 12;18(1):131
RFC2 promotes aerobic glycolysis and progression of colorectal cancer.
Lou F, Zhang M
BMC gastroenterology 2023 Oct 11;23(1):353
BMC gastroenterology 2023 Oct 11;23(1):353
miR-379-5P INHIBITION ENHANCES INTESTINAL EPITHELIAL PROLIFERATION AND BARRIER FUNCTION RECOVERY AFTER ISCHEMIA/REPERFUSION BY TARGETING EIF4G2.
Jia Z, Wang Y, Gao J, Zheng M, Wang P, Zu G
Shock (Augusta, Ga.) 2023 Oct 1;60(4):594-602
Shock (Augusta, Ga.) 2023 Oct 1;60(4):594-602
ANNEXIN A2 FACILITATES NEOVASCULARIZATION TO PROTECT AGAINST MYOCARDIAL INFARCTION INJURY VIA INTERACTING WITH MACROPHAGE YAP AND ENDOTHELIAL INTEGRIN Β3.
Zhang Y, Wang Y, Li J, Li C, Liu W, Long X, Wang Z, Zhao R, Ge J, Shi B
Shock (Augusta, Ga.) 2023 Oct 1;60(4):573-584
Shock (Augusta, Ga.) 2023 Oct 1;60(4):573-584
Inhibition of miR-543 alleviates cardiac fibroblast-to-myofibroblast transformation and collagen expression in insulin resistance via targeting PTEN.
Tan YM, Cao LY, Jiao YQ, Han L, Tang MX, Wang ZH, Zhang W, Zhong M, Zhang L
Molecular and cellular endocrinology 2023 Oct 1;576:111996
Molecular and cellular endocrinology 2023 Oct 1;576:111996
Oral administration of sophoricoside (SOP) inhibits neuronal damage and neuroinflammation to curb neurodegeneration in Parkinson's disease.
Wang H, He D, Li Z, Gao X, Yang S, Cui M, Ye B, Huang B, Fu S, Liu D
Chemico-biological interactions 2023 Oct 1;384:110726
Chemico-biological interactions 2023 Oct 1;384:110726
MiR-21-3p in extracellular vesicles from vascular fibroblasts of spontaneously hypertensive rat promotes proliferation and migration of vascular smooth muscle cells.
Zheng F, Ye C, Ge R, Wang Y, Tian XL, Chen Q, Li YH, Zhu GQ, Zhou B
Life sciences 2023 Oct 1;330:122023
Life sciences 2023 Oct 1;330:122023
Generation and application of a novel transgenic zebrafish line Tg(GAcyp1a:eGFP/Luc) as an in vivo assay to sensitive and specific monitoring of DLCs in the environment.
Xie S, Yang B, Li S, Ge L, Li M, Chen Q, Qing X, Zou J
Ecotoxicology and environmental safety 2023 Oct 1;264:115471
Ecotoxicology and environmental safety 2023 Oct 1;264:115471
Polydopamine-loaded prunetin nanomaterials activate DRD2 to reduce UV-induced inflammation by stabilizing and promoting Nrf2 nuclear translocation.
Han J, Zheng S, Jin J, Wu T, Shi Y, Yang K, Zhang H, Li Y, Sun Y, Lv Y, Yao C, Lin T, Zhu C, Liu H
Acta biomaterialia 2023 Oct 1;169:556-565
Acta biomaterialia 2023 Oct 1;169:556-565
FUT8-Mediated Core Fucosylation Promotes the Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension.
Zhang W, Lin W, Zeng X, Zhang M, Chen Q, Tang Y, Sun J, Liang B, Zha L, Yu Z
Aging and disease 2023 Oct 1;14(5):1927-1944
Aging and disease 2023 Oct 1;14(5):1927-1944
Clearance of Stress-Induced Premature Senescent Cells Alleviates the Formation of Abdominal Aortic Aneurysms.
Xie J, Tang Z, Chen Q, Jia X, Li C, Jin M, Wei G, Zheng H, Li X, Chen Y, Liao W, Liao Y, Bin J, Huang S
Aging and disease 2023 Oct 1;14(5):1778-1798
Aging and disease 2023 Oct 1;14(5):1778-1798
Overexpression of RACGAP1 by E2F1 Promotes Neuroendocrine Differentiation of Prostate Cancer by Stabilizing EZH2 Expression.
Song Z, Cao Q, Guo B, Zhao Y, Li X, Lou N, Zhu C, Luo G, Peng S, Li G, Chen K, Wang Y, Ruan H, Guo Y
Aging and disease 2023 Oct 1;14(5):1757-1774
Aging and disease 2023 Oct 1;14(5):1757-1774
Protective effect of GLP-1 analog liraglutide on podocytes in mice with diabetic nephropathy.
Shi S, Chen X, Yu W, Ke X, Ma T
Endocrine connections 2023 Oct 1;12(10)
Endocrine connections 2023 Oct 1;12(10)
Paternal lipopolysaccharide exposure induced intrauterine growth restriction via the inactivation of placental MEST/PI3K/AKT pathway in mice.
Jiang PY, Lin S, Liu JR, Liu Y, Zheng LM, Hong Q, Fan YJ, Xu DX, Chen YH
Archives of toxicology 2023 Nov;97(11):2929-2941
Archives of toxicology 2023 Nov;97(11):2929-2941
Mannan-binding lectin ameliorates renal fibrosis by suppressing macrophage-to-myofibroblast transition.
Xu L, Jiang H, Xie J, Xu Q, Zhou J, Lu X, Wang M, Dong L, Zuo D
Heliyon 2023 Nov;9(11):e21882
Heliyon 2023 Nov;9(11):e21882
Network pharmacology and in vivo studies reveal the neuroprotective effects of paeoniflorin on Alzheimer's disease.
Zhang M, Zheng H, He J, Zhang M
Heliyon 2023 Nov;9(11):e21800
Heliyon 2023 Nov;9(11):e21800
Nicotine plays a protective role in rats with induced viral pneumonia with polyinosinic-polycytidylic acid through α7nAChR.
Liu W, Zhu Y, Yan H, Ren L, Chen J
Heliyon 2023 Nov;9(11):e21667
Heliyon 2023 Nov;9(11):e21667
Global m6A methylation and gene expression patterns in human microglial HMC3 cells infected with HIV-1.
Peng Q, Qiao J, Li W, You Q, Hu S, Liu Y, Liu W, Hu K, Sun B
Heliyon 2023 Nov;9(11):e21307
Heliyon 2023 Nov;9(11):e21307
BTK inhibition potentiates anti-PD-L1 treatment in murine melanoma: potential role for MDSC modulation in immunotherapy.
Sun SH, Angell CD, Savardekar H, Sundi D, Abood D, Benner B, DiVincenzo MJ, Duggan M, Choueiry F, Mace T, Trikha P, Lapurga G, Johnson C, Carlson EJ, Chung C, Peterson BR, Lianbo Yu, Zhao J, Kendra KL, Carson WE 3rd
Cancer immunology, immunotherapy : CII 2023 Nov;72(11):3461-3474
Cancer immunology, immunotherapy : CII 2023 Nov;72(11):3461-3474
Local administration of liposomal-based Plekhf1 gene therapy attenuates pulmonary fibrosis by modulating macrophage polarization.
Yan L, Hou C, Liu J, Wang Y, Zeng C, Yu J, Zhou T, Zhou Q, Duan S, Xiong W
Science China. Life sciences 2023 Nov;66(11):2571-2586
Science China. Life sciences 2023 Nov;66(11):2571-2586
Protective effect of benzaldehyde combined with albendazole against brain injury induced by Angiostrongylus cantonensis infection in mice.
Chen KY, Cheng CJ, Chen YJ, Chiu CH, Wang LC
International journal of antimicrobial agents 2023 Nov;62(5):106963
International journal of antimicrobial agents 2023 Nov;62(5):106963
Catalpol Alleviates Ischemic Stroke Through Promoting Angiogenesis and Facilitating Proliferation and Differentiation of Neural Stem Cells via the VEGF-A/KDR Pathway.
Sun S, Xu Y, Yu N, Zhang M, Wang J, Wan D, Tian Z, Zhu H
Molecular neurobiology 2023 Nov;60(11):6227-6247
Molecular neurobiology 2023 Nov;60(11):6227-6247
Tanshinone IIA confers protection against myocardial ischemia/reperfusion injury by inhibiting ferroptosis and apoptosis via VDAC1.
Hu T, Zou HX, Le SY, Wang YR, Qiao YM, Yuan Y, Liu JC, Lai SQ, Huang H
International journal of molecular medicine 2023 Nov;52(5)
International journal of molecular medicine 2023 Nov;52(5)
Ligustrazine and liguzinediol protect against doxorubicin-induced cardiomyocytes injury by inhibiting mitochondrial apoptosis and autophagy.
Lian N, Tong J, Zhu W, Meng Q, Jiang M, Bian M, Li Y
Clinical and experimental pharmacology & physiology 2023 Nov;50(11):867-877
Clinical and experimental pharmacology & physiology 2023 Nov;50(11):867-877
Aucubin alleviates methotrexate-induced enteritis in rats by inducing autophagy.
Yang T, Lang W, Zhao Y, Yang Y, Liu H, Li S, Li X, Zhang S, Zhang H
Clinical and experimental pharmacology & physiology 2023 Nov;50(11):855-866
Clinical and experimental pharmacology & physiology 2023 Nov;50(11):855-866
Influences of lysine-specific demethylase 1 inhibitors on NO synthase-Kruppel-like factor pathways in human endothelial cells in vitro and zebrafish (Danio rerio) larvae in vivo.
Yuan J, Que R, Zhao W, Song F, Cao Y, Yu B
Journal of applied toxicology : JAT 2023 Nov;43(11):1748-1760
Journal of applied toxicology : JAT 2023 Nov;43(11):1748-1760
The ASH1L-AS1-ASH1L axis controls NME1-mediated activation of the RAS signaling in gastric cancer.
Xie M, Zhang L, Han L, Huang L, Huang Y, Yang M, Zhang N
Oncogene 2023 Nov;42(46):3435-3445
Oncogene 2023 Nov;42(46):3435-3445
mTOR/ULK1 signaling axis mediated ultrashort wave regulation of autophagy to alleviate diabetic kidney disease.
Yan Y, Yu S, Fan Y
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2023 Nov;32(11):1265-1277
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2023 Nov;32(11):1265-1277
Integrated network pharmacology to investigate the mechanism of Salvia miltiorrhiza Bunge in the treatment of myocardial infarction.
Huang X, Zhang M, Song Y, Sun B, Lin L, Song X, Li C
Journal of cellular and molecular medicine 2023 Nov;27(22):3514-3525
Journal of cellular and molecular medicine 2023 Nov;27(22):3514-3525
Avicularin alleviates acute liver failure by regulation of the TLR4/MyD88/NF-κB and Nrf2/HO-1/GPX4 pathways to reduce inflammation and ferroptosis.
Shi P, Zhu W, Fu J, Liang A, Zheng T, Wen Z, Wu X, Peng Y, Yuan S, Wu X
Journal of cellular and molecular medicine 2023 Nov;27(21):3326-3338
Journal of cellular and molecular medicine 2023 Nov;27(21):3326-3338
Macrophage-derived inflammation promotes pulmonary vascular remodeling in hypoxia-induced pulmonary arterial hypertension mice.
Liu H, Wang Y, Zhang Q, Liu C, Ma Y, Huang P, Ge R, Ma L
Immunology letters 2023 Nov;263:113-122
Immunology letters 2023 Nov;263:113-122
PCSK9 promotes tumor cell proliferation and migration by facilitating CCL25 secretion in esophageal squamous cell carcinoma.
Wang H, Guo Q, Wang M, Liu C, Tian Z
Oncology letters 2023 Nov;26(5):500
Oncology letters 2023 Nov;26(5):500
FOXO1 promotes endothelial cell elongation and angiogenesis by up-regulating the phosphorylation of myosin light chain 2.
Tsuji-Tamura K, Ogawa M
Angiogenesis 2023 Nov;26(4):523-545
Angiogenesis 2023 Nov;26(4):523-545
Uterine Fluid Extracellular Vesicles Proteome Is Altered During the Estrous Cycle.
Piibor J, Waldmann A, Dissanayake K, Andronowska A, Ivask M, Prasadani M, Kavak A, Kodithuwakku S, Fazeli A
Molecular & cellular proteomics : MCP 2023 Nov;22(11):100642
Molecular & cellular proteomics : MCP 2023 Nov;22(11):100642
Cucurbitacin C suppresses the progression of pancreatic ductal adenocarcinoma via inhibition of the cGMP-PKG-VASP axis.
Xu D, Liu A, Liu Q, Zhang H, Tian M, Bian Y, Zhang X, Ying M, Shen H
Biochemical pharmacology 2023 Nov;217:115810
Biochemical pharmacology 2023 Nov;217:115810
Molecular basis of inherited protein C deficiency results from genetic variations in the signal peptide and propeptide regions.
Cao Q, Hao Z, Li C, Chen X, Gao M, Jiang N, Liu H, Shen Y, Yang H, Zhang S, Yang A, Li W, Tie JK, Shen G
Journal of thrombosis and haemostasis : JTH 2023 Nov;21(11):3124-3137
Journal of thrombosis and haemostasis : JTH 2023 Nov;21(11):3124-3137
Antidepressant effects of 70% ethanolic extract of Lonicerae japonicae flos and it contained chlorogenic acid via upregulation of BDNF-TrkB pathway in the hippocampus of mice.
Qin L, Wang J, Wu X, Song L, Zhang Y, Gong M, Wang Y, Li B
Brain research bulletin 2023 Nov;204:110796
Brain research bulletin 2023 Nov;204:110796
Hyaluronan-CD44 Interaction Regulates Mouse Retinal Progenitor Cells Migration, Proliferation and Neuronal Differentiation.
Ma J, Fang X, Chen M, Wang Y, Zhang L
Stem cell reviews and reports 2023 Nov;19(8):2929-2942
Stem cell reviews and reports 2023 Nov;19(8):2929-2942
A Responsive Nanorobot Modulates Intracellular Zinc Homeostasis to Amplify Mitochondria-Targeted Phototherapy.
Zhou X, Zhou A, Tian Z, Chen W, Xu Y, Ning X, Chen K
Small (Weinheim an der Bergstrasse, Germany) 2023 Nov;19(45):e2302952
Small (Weinheim an der Bergstrasse, Germany) 2023 Nov;19(45):e2302952
CDN1163, an activator of sarco/endoplasmic reticulum Ca(2+) ATPase, up-regulates mitochondrial functions and protects against lipotoxicity in pancreatic β-cells.
Nguyen HT, Noriega Polo C, Wiederkehr A, Wollheim CB, Park KS
British journal of pharmacology 2023 Nov;180(21):2762-2776
British journal of pharmacology 2023 Nov;180(21):2762-2776
Peanut skin procyanidins reduce intestinal glucose transport protein expression, regulate serum metabolites and ameliorate hyperglycemia in diabetic mice.
Liu M, Shen J, Zhu X, Ju T, Willing BP, Wu X, Lu Q, Liu R
Food research international (Ottawa, Ont.) 2023 Nov;173(Pt 2):113471
Food research international (Ottawa, Ont.) 2023 Nov;173(Pt 2):113471
Effects of HMGB1/RAGE/cathespin B inhibitors on alleviating hippocampal injury by regulating microglial pyroptosis and caspase activation in neonatal hypoxic-ischemic brain damage.
Zhu K, Zhu X, Yu J, Chen L, Liu S, Yan M, Yang W, Sun Y, Zhang Z, Li J, Shen T, Hei M
Journal of neurochemistry 2023 Nov;167(3):410-426
Journal of neurochemistry 2023 Nov;167(3):410-426
Ginkgolic acid inhibits the replication of pseudorabies virus in vitro and in vivo by suppressing the transcription of viral late genes.
Bo Z, Wang S, Li X, Guo M, Zhang C, Cao Y, Zhang X, Wu Y
Research in veterinary science 2023 Nov;164:105033
Research in veterinary science 2023 Nov;164:105033
Anti-resorption role of low-intensity pulsed ultrasound (LIPUS) during large-scale bone reconstruction using porous titanium alloy scaffolds through inhibiting osteoclast differentiation.
Luo L, Cao H, Zhou L, Zhang G, Wu L
Biomaterials advances 2023 Nov;154:213634
Biomaterials advances 2023 Nov;154:213634
A positive feedback loop between miR-574-3p and HIF-1α in promoting angiogenesis under hypoxia.
Zhang R, Miao Z, Liu Y, Zhang X, Yang Q
Microvascular research 2023 Nov;150:104589
Microvascular research 2023 Nov;150:104589
New insights into the effect of VMP1 on the treatment of pressure overload-induced pathological cardiac hypertrophy: Involving SERCA-regulated autophagic flux.
Liu X, Du H, Pan Y, Li X
Microvascular research 2023 Nov;150:104572
Microvascular research 2023 Nov;150:104572
Characterization of STING from common carp (Cyprinus carpio L.) involved in spring viremia of carp virus infection.
Liu R, Meng F, Li X, Li H, Yang G, Shan S
Fish & shellfish immunology 2023 Nov;142:109164
Fish & shellfish immunology 2023 Nov;142:109164
Design, synthesis and biological evaluation of 4-arylamino-pyrimidine derivatives as focal adhesion kinase inhibitors.
Long Z, Zuo Y, Li R, Le Y, Dong Y, Yan L
Bioorganic chemistry 2023 Nov;140:106792
Bioorganic chemistry 2023 Nov;140:106792
Chitosan biomaterial enhances the effect of OECs on the inhibition of sciatic nerve injury-induced neuropathic pain.
Hu JL, Luo HL, Liu JP, Zuo C, Xu YS, Feng X, Zhang WJ
Journal of chemical neuroanatomy 2023 Nov;133:102327
Journal of chemical neuroanatomy 2023 Nov;133:102327
A natural sesquiterpene lactone isolinderalactone attenuates lipopolysaccharide-induced inflammatory response and acute lung injury through inhibition of NF-κB pathway and activation Nrf2 pathway in macrophages.
Shen X, Chen H, Zhang H, Luo L, Wen T, Liu L, Hu Q, Wang L
International immunopharmacology 2023 Nov;124(Pt B):110965
International immunopharmacology 2023 Nov;124(Pt B):110965
CTRP6 regulates M1 macrophage polarization via the PPAR-γ/NF-κB pathway and reprogramming glycolysis in recurrent spontaneous abortion.
Yan S, Ding J, Wang Z, Zhang F, Li J, Zhang Y, Wu S, Yang L, Pang X, Zhang Y, Yang J
International immunopharmacology 2023 Nov;124(Pt A):110840
International immunopharmacology 2023 Nov;124(Pt A):110840
Escin avoids hemorrhagic transformation in ischemic stroke by protecting BBB through the AMPK/Cav-1/MMP-9 pathway.
Sun X, Liu Z, Zhou L, Ma R, Zhang X, Wang T, Fu F, Wang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155071
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155071
Kaempferol ameliorated alcoholic liver disease through inhibiting hepatic bile acid synthesis by targeting intestinal FXR-FGF15 signaling.
Xiao L, Xu G, Chen S, He Y, Peng F, Yuan C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155055
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155055
Engineering high-affinity dual targeting cellular nanovesicles for optimised cancer immunotherapy.
Zhang L, Zhao X, Niu Y, Ma X, Yuan W, Ma J
Journal of extracellular vesicles 2023 Nov;12(11):e12379
Journal of extracellular vesicles 2023 Nov;12(11):e12379
Oxytocin alleviates cognitive and memory impairments by decreasing hippocampal microglial activation and synaptic defects via OXTR/ERK/STAT3 pathway in a mouse model of sepsis-associated encephalopathy.
Jiang J, Zou Y, Xie C, Yang M, Tong Q, Yuan M, Pei X, Deng S, Tian M, Xiao L, Gong Y
Brain, behavior, and immunity 2023 Nov;114:195-213
Brain, behavior, and immunity 2023 Nov;114:195-213
Whey protein peptides PEW and LLW synergistically ameliorate hyperuricemia and modulate gut microbiota in potassium oxonate and hypoxanthine-induced hyperuricemic rats.
Qi X, Guan K, Liu C, Chen H, Ma Y, Wang R
Journal of dairy science 2023 Nov;106(11):7367-7381
Journal of dairy science 2023 Nov;106(11):7367-7381
Aryl hydrocarbon receptor regulates IL-22 receptor expression on thymic epithelial cell and accelerates thymus regeneration.
Shen J, Wang Y, Zheng F, Cao S, Lan Q, Xu K, Pan B
NPJ Regenerative medicine 2023 Nov 8;8(1):64
NPJ Regenerative medicine 2023 Nov 8;8(1):64
Transcriptomic Profiling Reveals Claudin 18.2 as a Diagnostic Biomarker of Ménétrier's Disease and the Role of Hedgehog Signaling in Pathogenesis.
Shin M, Gabriel T, Coffey RJ, Huh WJ
bioRxiv : the preprint server for biology 2023 Nov 6;
bioRxiv : the preprint server for biology 2023 Nov 6;
Platycodin D inhibits glioblastoma cell proliferation, migration, and invasion by regulating DEPDC1B-mediated epithelial-to-mesenchymal transition.
Ouyang J, Li H, Wu G, Hei B, Liu R
European journal of pharmacology 2023 Nov 5;958:176074
European journal of pharmacology 2023 Nov 5;958:176074
Quercetin Attenuates the Combined Effects of Zearalenone and Lipopolysaccharide on IPEC-J2 Cell Injury through Activating the Nrf2 Signaling Pathway.
Wang C, Fu Y, Wang R, Wang Q, Yu H, Zhang J
Toxins 2023 Nov 30;15(12)
Toxins 2023 Nov 30;15(12)
Plumbagin has an inhibitory effect on the growth of TSCC PDX model and it enhances the anticancer efficacy of cisplatin.
Xin Y, Jiang Q, Liu C, Qiu J
Aging 2023 Nov 3;15(21):12225-12250
Aging 2023 Nov 3;15(21):12225-12250
Porcine promyelocytic leukemia protein isoforms suppress Japanese encephalitis virus replication in PK15 cells.
Chen Z, Liu H, Zhu J, Duan X, Wang H, Li X, Zhou X, Zhao A, Yang S
Virology journal 2023 Nov 29;20(1):280
Virology journal 2023 Nov 29;20(1):280
Inhibiting G6PD by quercetin promotes degradation of EGFR T790M mutation.
Ge Z, Xu M, Ge Y, Huang G, Chen D, Ye X, Xiao Y, Zhu H, Yin R, Shen H, Ma G, Qi L, Wei G, Li D, Wei S, Zhu M, Ma H, Shi Z, Wang X, Ge X, Qian X
Cell reports 2023 Nov 28;42(11):113417
Cell reports 2023 Nov 28;42(11):113417
Osteopontin enhances the effect of treadmill training and promotes functional recovery after spinal cord injury.
Wang Y, Su H, Zhong J, Zhan Z, Zhao Q, Liu Y, Li S, Wang H, Yang C, Yu L, Tan B, Yin Y
Molecular biomedicine 2023 Nov 28;4(1):44
Molecular biomedicine 2023 Nov 28;4(1):44
Dopaminergic Projections from the Hypothalamic A11 Nucleus to the Spinal Trigeminal Nucleus Are Involved in Bidirectional Migraine Modulation.
Li C, Li Y, Zhang W, Ma Z, Xiao S, Xie W, Miao S, Li B, Lu G, Liu Y, Bai W, Yu S
International journal of molecular sciences 2023 Nov 28;24(23)
International journal of molecular sciences 2023 Nov 28;24(23)
Schwann Cell-Derived Exosomes and Methylprednisolone Composite Patch for Spinal Cord Injury Repair.
Zhu B, Gu G, Ren J, Song X, Li J, Wang C, Zhang W, Huo Y, Wang H, Jin L, Feng S, Wei Z
ACS nano 2023 Nov 28;17(22):22928-22943
ACS nano 2023 Nov 28;17(22):22928-22943
miR-196a Promotes Proliferation of Mammary Epithelial Cells by Targeting CDKN1B.
Chen G, Sun W, Li Y, Li M, Jia X, Wang J, Lai S
Animals : an open access journal from MDPI 2023 Nov 28;13(23)
Animals : an open access journal from MDPI 2023 Nov 28;13(23)
PDK4 rescues high-glucose-induced senescent fibroblasts and promotes diabetic wound healing through enhancing glycolysis and regulating YAP and JNK pathway.
Ma Z, Ding Y, Ding X, Mou H, Mo R, Tan Q
Cell death discovery 2023 Nov 25;9(1):424
Cell death discovery 2023 Nov 25;9(1):424
ACO2 deficiency increases vulnerability to Parkinson's disease via dysregulating mitochondrial function and histone acetylation-mediated transcription of autophagy genes.
Zhu J, Xu F, Lai H, Yuan H, Li XY, Hu J, Li W, Liu L, Wang C
Communications biology 2023 Nov 25;6(1):1201
Communications biology 2023 Nov 25;6(1):1201
Role of DCLK1/Hippo pathway in type II alveolar epithelial cells differentiation in acute respiratory distress syndrome.
Chen XY, Kao C, Peng SW, Chang JH, Lee YL, Laiman V, Chung KF, Bhavsar PK, Heriyanto DS, Chuang KJ, Chuang HC
Molecular medicine (Cambridge, Mass.) 2023 Nov 23;29(1):159
Molecular medicine (Cambridge, Mass.) 2023 Nov 23;29(1):159
Circular RNA ZBTB46 depletion alleviates the progression of Atherosclerosis by regulating the ubiquitination and degradation of hnRNPA2B1 via the AKT/mTOR pathway.
Fu Y, Jia Q, Ren M, Bie H, Zhang X, Zhang Q, He S, Li C, Zhou H, Wang Y, Gan X, Tao Z, Chen X, Jia E
Immunity & ageing : I & A 2023 Nov 21;20(1):66
Immunity & ageing : I & A 2023 Nov 21;20(1):66
DJ1 Ameliorates AD-like Pathology in the Hippocampus of APP/PS1 Mice.
Peng YY, Li MX, Li WJ, Xue Y, Miao YF, Wang YL, Fan XC, Tang LL, Song HL, Zhang Q, Li X
Biomedical and environmental sciences : BES 2023 Nov 20;36(11):1028-1044
Biomedical and environmental sciences : BES 2023 Nov 20;36(11):1028-1044
Role of the p38/AKT Pathway in the Promotion of Cell Proliferation by Serum Heat Inactivation.
Geng H, Li R, Feng D, Zhu Y, Deng L
International journal of molecular sciences 2023 Nov 20;24(22)
International journal of molecular sciences 2023 Nov 20;24(22)
BCAS2 Participates in Insulin Synthesis and Secretion via mRNA Alternative Splicing in Mice.
Chen X, Xie X, Li J, Sun L, Lv Z, Yao X, Li L, Jin H, Cui S, Liu J
Endocrinology 2023 Nov 20;165(1)
Endocrinology 2023 Nov 20;165(1)
Attenuation of estrogen and its receptors in the post-menopausal stage exacerbates dyslipidemia and leads to cognitive impairment.
Meng Q, Chao Y, Zhang S, Ding X, Feng H, Zhang C, Liu B, Zhu W, Li Y, Zhang Q, Tong H, Wu L, Bian H
Molecular brain 2023 Nov 20;16(1):80
Molecular brain 2023 Nov 20;16(1):80
PHB2 Alleviates Neurotoxicity of Prion Peptide PrP(106-126) via PINK1/Parkin-Dependent Mitophagy.
Zheng X, Liu K, Xie Q, Xin H, Chen W, Lin S, Feng D, Zhu T
International journal of molecular sciences 2023 Nov 2;24(21)
International journal of molecular sciences 2023 Nov 2;24(21)
TRPV4 enhances the synthesis of fatty acids to drive the progression of ovarian cancer through the calcium-mTORC1/SREBP1 signaling pathway.
Lin L, Li X, Wu AJ, Xiu JB, Gan YZ, Yang XM, Ai ZH
iScience 2023 Nov 17;26(11):108226
iScience 2023 Nov 17;26(11):108226
Inhibition of Hsp110-STAT3 interaction in endothelial cells alleviates vascular remodeling in hypoxic pulmonary arterial Hypertension model.
Zhao C, Le X, Li M, Hu Y, Li X, Chen Z, Hu G, Hu L, Li Q
Respiratory research 2023 Nov 17;24(1):289
Respiratory research 2023 Nov 17;24(1):289
WGX50 mitigates doxorubicin-induced cardiotoxicity through inhibition of mitochondrial ROS and ferroptosis.
Tai P, Chen X, Jia G, Chen G, Gong L, Cheng Y, Li Z, Wang H, Chen A, Zhang G, Zhu Y, Xiao M, Wang Z, Liu Y, Shan D, He D, Li M, Zhan T, Khan A, Li X, Zeng X, Li C, Ouyang D, Ai K, Chen X, Liu D, Liu Z, Wei D, Cao K
Journal of translational medicine 2023 Nov 17;21(1):823
Journal of translational medicine 2023 Nov 17;21(1):823
Crucial role of hsa-mir-503, hsa-mir-1247, and their validation in prostate cancer.
Hu P, Wang T, Yan H, Huang Y, Zhao Y, Gao Y
Aging 2023 Nov 16;15(22):12966-12981
Aging 2023 Nov 16;15(22):12966-12981
LCMR1 Promotes Large-Cell Lung Cancer Proliferation and Metastasis by Downregulating HLA-Encoding Genes.
Liu L, Li C, Wu Z, Li Y, Yu H, Li T, Wang Y, Zhao W, Chen L
Cancers 2023 Nov 16;15(22)
Cancers 2023 Nov 16;15(22)
Tripartite motif 31 drives gastric cancer cell proliferation and invasion through activating the Wnt/β-catenin pathway by regulating Axin1 protein stability.
Feng Q, Nie F, Gan L, Wei X, Liu P, Liu H, Zhang K, Fang Z, Wang H, Fang N
Scientific reports 2023 Nov 16;13(1):20099
Scientific reports 2023 Nov 16;13(1):20099
The protective effects of uric acid against myocardial ischemia via the Nrf2 pathway.
Ma P, Zhao M, Li Y, Zhang G, Ma Y, Shi Y, Su P, Chen R, Tang ZG, Zhang Y, Liu B, Zhang Q, Liu X, Li F
European journal of pharmacology 2023 Nov 15;959:176062
European journal of pharmacology 2023 Nov 15;959:176062
Genetic Ablation of GIGYF1, Associated With Autism, Causes Behavioral and Neurodevelopmental Defects in Zebrafish and Mice.
Ding Z, Huang G, Wang T, Duan W, Li H, Wang Y, Jia H, Yang Z, Wang K, Chu X, Kurtz-Nelson EC, Ahlers K, Earl RK, Han Y, Feliciano P, Chung WK, Eichler EE, Jiang M, Xiong B
Biological psychiatry 2023 Nov 15;94(10):769-779
Biological psychiatry 2023 Nov 15;94(10):769-779
BSHXF-medicated serum combined with ADSCs regulates the TGF-β1/Smad pathway to repair oxidatively damaged NPCs and its component analysis.
Duan J, Li Z, Liu E, Long H, Chen L, Yang S
Journal of ethnopharmacology 2023 Nov 15;316:116692
Journal of ethnopharmacology 2023 Nov 15;316:116692
Discovery of novel flavonoid-based CDK9 degraders for prostate cancer treatment via a PROTAC strategy.
Wu T, Zhang Z, Gong G, Du Z, Xu Y, Yu S, Ma F, Zhang X, Wang Y, Chen H, Wu S, Xu X, Qiu Z, Li Z, Wu H, Bian J, Wang J
European journal of medicinal chemistry 2023 Nov 15;260:115774
European journal of medicinal chemistry 2023 Nov 15;260:115774
Curcumin enhances elvitegravir concentration and alleviates oxidative stress and inflammatory response.
Godse S, Zhou L, Sinha N, Kodidela S, Kumar A, Singh UP, Kumar S
Scientific reports 2023 Nov 14;13(1):19864
Scientific reports 2023 Nov 14;13(1):19864
Pathological roles of bone marrow adipocyte-derived monocyte chemotactic protein-1 in type 2 diabetic mice.
Wan S, Xie J, Liang Y, Yu X
Cell death discovery 2023 Nov 13;9(1):412
Cell death discovery 2023 Nov 13;9(1):412
GSK2656157, a PERK Inhibitor, Alleviates Pyroptosis of Macrophages Induced by Mycobacterium Bacillus Calmette-Guerin Infection.
Ma B, Nie X, Liu L, Li M, Chen Q, Liu Y, Hou Y, Yang Y, Xu J
International journal of molecular sciences 2023 Nov 12;24(22)
International journal of molecular sciences 2023 Nov 12;24(22)
Circ_16601 facilitates Hippo pathway signaling via the miR-5580-5p/FGB axis to promote my-CAF recruitment in the TME and LUAD progression.
Zhou J, Li P, Zhao X, Zhao Y, Luo J, Deng Y, Jiang N, Xiao Z, Zhang W, Zhou Y, Zhao J, Li P, Li Y, Tian Z
Respiratory research 2023 Nov 12;24(1):276
Respiratory research 2023 Nov 12;24(1):276
High expression of CDKN2A is associated with poor prognosis in colorectal cancer and may guide PD-1-mediated immunotherapy.
Dong Y, Zheng M, Wang X, Yu C, Qin T, Shen X
BMC cancer 2023 Nov 11;23(1):1097
BMC cancer 2023 Nov 11;23(1):1097
Peptidome analysis reveals critical roles for peptides in a rat model of intestinal ischemia/reperfusion injury.
Zhang J, Jiang X, Yang Y, Yang L, Lu B, Ji Y, Guo L, Zhang F, Xue J, Zhi X
Aging 2023 Nov 10;15(22):12852-12872
Aging 2023 Nov 10;15(22):12852-12872
Green Pea (Pisum sativum L.) Hull Polyphenol Extract Alleviates NAFLD through VB6/TLR4/NF-κB and PPAR Pathways.
Guo F, Xiong H, Tsao R, Shahidi F, Wen X, Liu J, Jiang L, Sun Y
Journal of agricultural and food chemistry 2023 Nov 1;71(43):16067-16078
Journal of agricultural and food chemistry 2023 Nov 1;71(43):16067-16078
NF-κB c-Rel Is a Potential Therapeutic Target for Acute Corneal Transplant Rejection.
Zheng Q, Liu R, Jiang B, Sun J, Wang T, Ruan Q
Investigative ophthalmology & visual science 2023 Nov 1;64(14):16
Investigative ophthalmology & visual science 2023 Nov 1;64(14):16
Cholesterol mediated ferroptosis suppression reveals essential roles of Coenzyme Q and squalene.
Sun Q, Liu D, Cui W, Cheng H, Huang L, Zhang R, Gu J, Liu S, Zhuang X, Lu Y, Chu B, Li J
Communications biology 2023 Nov 1;6(1):1108
Communications biology 2023 Nov 1;6(1):1108
The HDAC inhibitor HFY-4A improves TUSC2 transcription to induce immunogenic cell death in breast cancer.
Yin Y, Guan X, Li G, Chen C, Duan Y, Yu Z
Toxicology and applied pharmacology 2023 Nov 1;478:116698
Toxicology and applied pharmacology 2023 Nov 1;478:116698
ADAR1 affects gastric cancer cell metastasis and reverses cisplatin resistance through AZIN1.
Wang H, Yang L, Liu R, He H, Zhang M, Xu Y
Anti-cancer drugs 2023 Nov 1;34(10):1132-1145
Anti-cancer drugs 2023 Nov 1;34(10):1132-1145
Tert-butyl hydroperoxide induces ferroptosis of bone mesenchymal stem cells by repressing the prominin2/BACH1/ROS axis.
Xu Y, Fan P, Xu X, Liu L, Zhang L, Li X, Wang J, Tao Y, Li X, Xu D, Wang X, Zhou Y, Wang Y
American journal of physiology. Cell physiology 2023 Nov 1;325(5):C1212-C1227
American journal of physiology. Cell physiology 2023 Nov 1;325(5):C1212-C1227
CAB39 promotes cisplatin resistance in bladder cancer via the LKB1-AMPK-LC3 pathway.
Gao D, Wang R, Gong Y, Yu X, Niu Q, Yang E, Fan G, Ma J, Chen C, Tao Y, Lu J, Wang Z
Free radical biology & medicine 2023 Nov 1;208:587-601
Free radical biology & medicine 2023 Nov 1;208:587-601
5-(3',4'-dihydroxyphenyl)-γ-valerolactone, a microbiota metabolite of flavan-3-ols, activates SIRT1-mediated autophagy to attenuate H₂O₂-induced inhibition of osteoblast differentiation in MC3T3-E1 cells.
Chen F, Zhang X, Chen S, Wu Y, Wei Q, Chu X, Zhang Z
Free radical biology & medicine 2023 Nov 1;208:309-318
Free radical biology & medicine 2023 Nov 1;208:309-318
A phosphoglycerate mutase 1 allosteric inhibitor overcomes drug resistance to EGFR-targeted therapy via disrupting IL-6/JAK2/STAT3 signaling pathway in lung adenocarcinoma.
Liang Q, Gong M, Zou JH, Luo MY, Jiang LL, Wang C, Shen NX, Zhang MC, Xu L, Lei HM, Zhang KR, Zhang R, Zhuang G, Zhu L, Chen HZ, Zhou L, Shen Y
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2023 May;68:100957
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2023 May;68:100957
TREM2 Inhibits Tau Hyperphosphorylation and Neuronal Apoptosis via the PI3K/Akt/GSK-3β Signaling Pathway In vivo and In vitro.
Peng X, Guo H, Zhang X, Yang Z, Ruganzu JB, Yang Z, Wu X, Bi W, Ji S, Yang W
Molecular neurobiology 2023 May;60(5):2470-2485
Molecular neurobiology 2023 May;60(5):2470-2485
Zika virus replication on endothelial cells and invasion into the central nervous system by inhibiting interferon β translation.
Wang K, Zou S, Chen H, Higazy D, Gao X, Zhang Y, Cao S, Cui M
Virology 2023 May;582:23-34
Virology 2023 May;582:23-34
Endothelial Arid1a deletion disrupts the balance among angiogenesis, neurogenesis and gliogenesis in the developing brain.
Wang Y, Su L, Wang W, Zhao J, Wang Y, Li S, Liu Y, Chai R, Li X, Teng Z, Liu C, Hu B, Ji F, Jiao J
Cell proliferation 2023 May;56(5):e13447
Cell proliferation 2023 May;56(5):e13447
Suprabasin enhances the invasion, migration, and angiogenic ability of oral squamous cell carcinoma cells under hypoxic conditions.
Houri A, Mukudai Y, Abe Y, Watanabe M, Nara M, Miyamoto S, Kurihara M, Shimane T, Shirota T
Oncology reports 2023 May;49(5)
Oncology reports 2023 May;49(5)
HSF4 promotes tumor progression of colorectal cancer by transactivating c-MET.
Zhang W, Zhang X, Cheng P, Yue K, Tang M, Li Y, Guo Q, Zhang Y
Molecular and cellular biochemistry 2023 May;478(5):1141-1150
Molecular and cellular biochemistry 2023 May;478(5):1141-1150
Remote Ischemic Conditioning Relieves Necrotizing Enterocolitis Through Regulation of Redox and Inflammation.
Zhang Y, Liu Q, Gao K, Tian B, Zhu H, Liu J, Hu Y, Ye C, Guo C
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2023 May;43(5):216-228
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2023 May;43(5):216-228
Sirt1 protects against intervertebral disc degeneration induced by 1,25-dihydroxyvitamin D insufficiency in mice by inhibiting the NF-κB inflammatory pathway.
Wang P, Yang C, Lu J, Ren Y, Goltzman D, Miao D
Journal of orthopaedic translation 2023 May;40:13-26
Journal of orthopaedic translation 2023 May;40:13-26
Mesenchymal stem cells ameliorate cisplatin-induced acute kidney injury via let-7b-5p.
Wang SY, Xu Y, Hong Q, Chen XM, Cai GY
Cell and tissue research 2023 May;392(2):517-533
Cell and tissue research 2023 May;392(2):517-533
Thalamocortical Circuit Controls Neuropathic Pain via Up-regulation of HCN2 in the Ventral Posterolateral Thalamus.
Yan Y, Zhu M, Cao X, Xu G, Shen W, Li F, Zhang J, Luo L, Zhang X, Zhang D, Liu T
Neuroscience bulletin 2023 May;39(5):774-792
Neuroscience bulletin 2023 May;39(5):774-792
AdipoRon mitigates tau pathology and restores mitochondrial dynamics via AMPK-related pathway in a mouse model of Alzheimer's disease.
Wang C, Chang Y, Zhu J, Wu Y, Jiang X, Zheng S, Li G, Ma R
Experimental neurology 2023 May;363:114355
Experimental neurology 2023 May;363:114355
CircRNA_0017076 acts as a sponge for miR-185-5p in the control of epithelial-to-mesenchymal transition of tubular epithelial cells during renal interstitial fibrosis.
Zhang F, Zou H, Li X, Liu J, Xie Y, Chen M, Yu J, Wu X, Guo B
Human cell 2023 May;36(3):1024-1040
Human cell 2023 May;36(3):1024-1040
BAP18 facilitates CTCF-mediated chromatin accessible to regulate enhancer activity in breast cancer.
Sun G, Wei Y, Zhou B, Wang M, Luan R, Bai Y, Li H, Wang S, Zheng D, Wang C, Wang S, Zeng K, Liu S, Lin L, He M, Zhang Q, Zhao Y
Cell death and differentiation 2023 May;30(5):1260-1278
Cell death and differentiation 2023 May;30(5):1260-1278
miR-27a-3p relieves heat stress-induced mitochondrial damage and aberrant milk protein synthesis through MEK/ERK pathway in BMECs.
Wang Y, Wu J, Xia SW, Zhao F, Ding Q, Ye XM, Zhong JF, Chen KL, Wang HL
Cell stress & chaperones 2023 May;28(3):265-274
Cell stress & chaperones 2023 May;28(3):265-274
Methionine alleviates heat stress-induced ferroptosis in bovine mammary epithelial cells through the Nrf2 pathway.
Xu J, Wang XL, Zeng HF, Han ZY
Ecotoxicology and environmental safety 2023 May;256:114889
Ecotoxicology and environmental safety 2023 May;256:114889
SEL1L-HRD1 endoplasmic reticulum-associated degradation controls STING-mediated innate immunity by limiting the size of the activable STING pool.
Ji Y, Luo Y, Wu Y, Sun Y, Zhao L, Xue Z, Sun M, Wei X, He Z, Wu SA, Lin LL, Lu Y, Chang L, Chen F, Chen S, Qian W, Xu X, Chen S, Pan D, Zhou Z, Xia S, Hu CA, Liang T, Qi L
Nature cell biology 2023 May;25(5):726-739
Nature cell biology 2023 May;25(5):726-739
Neutrophil membrane-camouflaged nanoparticles alleviate inflammation and promote angiogenesis in ischemic myocardial injury.
Han D, Wang F, Qiao Z, Wang B, Zhang Y, Jiang Q, Liu M, Zhuang Y, An Q, Bai Y, Shangguan J, Zhang J, Liang G, Shen D
Bioactive materials 2023 May;23:369-382
Bioactive materials 2023 May;23:369-382
Irisin attenuates fine particulate matter induced acute lung injury by regulating Nod2/NF-κB signaling pathway.
Jiao R, Han Z, Ma J, Wu S, Wang Z, Zhou G, Liu X, Li J, Yan X, Meng A
Immunobiology 2023 May;228(3):152358
Immunobiology 2023 May;228(3):152358
Lyn attenuates sepsis-associated acute kidney injury by inhibition of phospho-STAT3 and apoptosis.
Li N, Lin G, Zhang H, Sun J, Gui M, Liu Y, Li W, Zhan Z, Li Y, Pan S, Liu J, Tang J
Biochemical pharmacology 2023 May;211:115523
Biochemical pharmacology 2023 May;211:115523
The Bcr-Abl inhibitor DCC-2036 inhibits necroptosis and ameliorates osteoarthritis by targeting RIPK1 and RIPK3 kinases.
Piao L, Wu D, Rui C, Yang Y, Liu S, Liu J, Jin Z, Zhang H, Feng X, Bai L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114528
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114528
Identification of MAP Kinase Kinase 3 as a protein target of myricetin in non-small cell lung cancer cells.
Gu L, Li Z, Zhang X, Chen M, Zhang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114460
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114460
Ribosomal protein L32 enhances hepatocellular carcinoma progression.
Hou G, Lu Z, Jiang J, Yang X
Cancer medicine 2023 May;12(9):10791-10803
Cancer medicine 2023 May;12(9):10791-10803
Hypoxia disrupts the nasal epithelial barrier by inhibiting PTPN2 in chronic rhinosinusitis with nasal polyps.
Zhang M, Xiong Y, Tu J, Tang B, Zhang Z, Yu J, Shen L, Luo Q, Ye J
International immunopharmacology 2023 May;118:110054
International immunopharmacology 2023 May;118:110054
Lipin2 ameliorates diabetic encephalopathy via suppressing JNK/ERK-mediated NLRP3 inflammasome overactivation.
Zhang X, Huang S, Zhuang Z, Han X, Xie M, Yu S, Hua M, Liang Z, Meng C, Yin L, Zhuang X, Chen S
International immunopharmacology 2023 May;118:109930
International immunopharmacology 2023 May;118:109930
Aescin can alleviate NAFLD through Keap1-Nrf2 by activating antioxidant and autophagy.
Yu H, Yan S, Jin M, Wei Y, Zhao L, Cheng J, Ding L, Feng H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 May;113:154746
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 May;113:154746
Jiang-Tang-San-Huang pill alleviates type 2 diabetes mellitus through modulating the gut microbiota and bile acids metabolism.
Tawulie D, Jin L, Shang X, Li Y, Sun L, Xie H, Zhao J, Liao J, Zhu Z, Cui H, Wen W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 May;113:154733
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 May;113:154733
P4HA1 activates HMGCS1 to promote nasopharyngeal carcinoma ferroptosis resistance and progression.
Zhou R, Qiu L, Zhou L, Geng R, Yang S, Wu J
Cellular signalling 2023 May;105:110609
Cellular signalling 2023 May;105:110609
Autophagy ameliorates Pseudomonas aeruginosa-infected diabetic wounds by regulating the toll-like receptor 4/myeloid differentiation factor 88 pathway.
Ji X, Jin P, Yu P, Wang P
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2023 May-Jun;31(3):305-320
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2023 May-Jun;31(3):305-320
MC1R Peptide Agonist Self-Assembles into a Hydrogel That Promotes Skin Pigmentation for Treating Vitiligo.
Zhu C, Li T, Wang Z, Li Z, Wei J, Han H, Yuan D, Cai M, Shi J
ACS nano 2023 May 9;17(9):8723-8733
ACS nano 2023 May 9;17(9):8723-8733
RNA N6-methyladenosine reader IGF2BP3 interacts with MYCN and facilitates neuroblastoma cell proliferation.
Zhu K, Gao T, Wang Z, Zhang L, Tan K, Lv Z
Cell death discovery 2023 May 8;9(1):151
Cell death discovery 2023 May 8;9(1):151
Sp1 promotes tumour progression by remodelling the mitochondrial network in cervical cancer.
Xu X, Wang X, Chen Q, Zheng A, Li D, Meng Z, Li X, Cai H, Li W, Huang S, Wang F
Journal of translational medicine 2023 May 6;21(1):307
Journal of translational medicine 2023 May 6;21(1):307
Nicaraven protects against endotoxemia-induced inflammation and organ injury through modulation of AMPK/Sirt1 signaling in macrophages.
Zha D, Yang Y, Huang X, Wang Z, Lin H, Yang L, Xu L, Wu Y, Huang H, Wang Y, Xin Z, Wu X, Xiao YF, Li TS, Deng KY, Xin HB, Qian Y
European journal of pharmacology 2023 May 5;946:175666
European journal of pharmacology 2023 May 5;946:175666
Colocalization of Chikungunya Virus with Its Receptor MXRA8 during Cell Attachment, Internalization, and Membrane Fusion.
Feng F, Bouma EM, Hu G, Zhu Y, Yu Y, Smit JM, Diamond MS, Zhang R
Journal of virology 2023 May 31;97(5):e0155722
Journal of virology 2023 May 31;97(5):e0155722
Lactoferrin Relieves Deoxynivalenol-Induced Oxidative Stress and Inflammatory Response by Modulating the Nrf2/MAPK Pathways in the Liver.
Hu P, Liu Y, Li S, Zhao Y, Gu H, Zong Q, Ahmed AA, Bao W, Liu HY, Cai D
Journal of agricultural and food chemistry 2023 May 31;71(21):8182-8191
Journal of agricultural and food chemistry 2023 May 31;71(21):8182-8191
The effect of epigenetic reprogramming using MI192 HDAC inhibitor on enhancing the osteogenesis of human adipose-derived stem cells in vitro.
Lu W, Ji K, Lawlor L, Saha S, Hempshall A, Jin Y, Yang XB
Bioscience reports 2023 May 31;43(5)
Bioscience reports 2023 May 31;43(5)
E7050 Suppresses the Growth of Multidrug-Resistant Human Uterine Sarcoma by Inhibiting Angiogenesis via Targeting of VEGFR2-Mediated Signaling Pathways.
Huang TT, Chen CM, Lin SS, Lan YW, Cheng HC, Choo KB, Wang CC, Huang TH, Chong KY
International journal of molecular sciences 2023 May 31;24(11)
International journal of molecular sciences 2023 May 31;24(11)
Gasdermin D Plays an Oncogenic Role in Glioma and Correlates to an Immunosuppressive Microenvironment.
Li M, Jiang P, Wei S, Yang Y, Xiong L, Wang J, Li C
Biomolecules 2023 May 29;13(6)
Biomolecules 2023 May 29;13(6)
Identification of an LDLR variant in a Chinese familial hypercholesterolemia and its relation to ROS/NLRP3-Mediated pyroptosis in hepatic cells.
Cheng WZ, Wang WH, Deng AP, Dang X, Liu C, Wang XC, Li JY, Jin S
Journal of geriatric cardiology : JGC 2023 May 28;20(5):341-349
Journal of geriatric cardiology : JGC 2023 May 28;20(5):341-349
LEM Domain Containing 1 Acts as a Novel Oncogene and Therapeutic Target for Triple-Negative Breast Cancer.
Li X, Jiang S, Jiang T, Sun X, Guan Y, Fan S, Cheng Y
Cancers 2023 May 26;15(11)
Cancers 2023 May 26;15(11)
QiShenYiQi dripping pill alleviates myocardial ischemia-induced ferroptosis via improving mitochondrial dynamical homeostasis and biogenesis.
Wu L, Fan Z, Gu L, Liu J, Cui Z, Yu B, Kou J, Li F
Journal of ethnopharmacology 2023 May 23;308:116282
Journal of ethnopharmacology 2023 May 23;308:116282
Wei-Tong-Xin ameliorated cisplatin-induced mitophagy and apoptosis in gastric antral mucosa by activating the Nrf2/HO-1 pathway.
Zhang X, Wang S, Jin Y, Wang J, Wang R, Yang X, Zhang S, Yan T, Jia Y
Journal of ethnopharmacology 2023 May 23;308:116253
Journal of ethnopharmacology 2023 May 23;308:116253
Benzothiazole Substitution Analogs of Rhodacyanine Hsp70 Inhibitors Modulate Tau Accumulation.
Hill SE, Beaulieu-Abdelahad D, Lemus A, Webster JM, Ospina SR, Darling AL, Martin MD, Patel S, Bridenstine L, Swonger R, Paul S, Blackburn R, Calcul L, Dickey CA, Leahy JW, Blair LJ
ACS chemical biology 2023 May 19;18(5):1124-1135
ACS chemical biology 2023 May 19;18(5):1124-1135
Role of Protein Tyrosine Phosphatase 1B Inhibitor in Early Brain Injury of Subarachnoid Hemorrhage in Mice.
Zhang ZH, Zhou XM, Zhang X
Brain sciences 2023 May 18;13(5)
Brain sciences 2023 May 18;13(5)
Mitophagy associated self-degradation of phosphorylated MAP4 guarantees the migration and proliferation responses of keratinocytes to hypoxia.
Feng Y, Li L, Zhang Q, He Y, Huang Y, Zhang J, Zhang D, Huang Y, Lei X, Hu J, Luo G
Cell death discovery 2023 May 17;9(1):168
Cell death discovery 2023 May 17;9(1):168
A New Method for Programmable RNA Editing Using CRISPR Effector Cas13X.1.
Li L, Liu W, Zhang H, Cai Q, Wen D, Du J, Sun J, Li L, Gao C, Lin P, Wu M, Jiang J
The Tohoku journal of experimental medicine 2023 May 17;260(1):51-61
The Tohoku journal of experimental medicine 2023 May 17;260(1):51-61
Impact of age on the rotenone-induced sporadic Parkinson's disease model using Drosophila melanogaster.
Li W, Pan X, Li M, Ling L, Zhang M, Liu Z, Zhang K, Guo J, Wang H
Neuroscience letters 2023 May 14;805:137187
Neuroscience letters 2023 May 14;805:137187
Knock-down of PGM1 inhibits cell viability, glycolysis, and oxidative phosphorylation in glioma under low glucose condition via the Myc signaling pathway.
Liu S, Deng Y, Yu Y, Xia X
Biochemical and biophysical research communications 2023 May 14;656:38-45
Biochemical and biophysical research communications 2023 May 14;656:38-45
Mutation-Driven S100A8 Overexpression Confers Aberrant Phenotypes in Type 1 CALR-Mutated MPN.
Wang YH, Chen YJ, Lai YH, Wang MC, Chen YY, Wu YY, Yang YR, Tsou HY, Li CP, Hsu CC, Huang CE, Chen CC
International journal of molecular sciences 2023 May 14;24(10)
International journal of molecular sciences 2023 May 14;24(10)
Vitamin D receptor attenuate ischemia-reperfusion kidney injury via inhibiting ATF4.
Tang S, Wu X, Dai Q, Li Z, Yang S, Liu Y, Yi B, Wang J, Liao Q, Zhang W, Zhang H
Cell death discovery 2023 May 12;9(1):158
Cell death discovery 2023 May 12;9(1):158
Yishen Tongluo formula alleviates diabetic kidney disease through regulating Sirt6/TGF-β1/Smad2/3 pathway and promoting degradation of TGF-β1.
Zhang X, Zhao L, Xiang S, Sun Y, Wang P, Chen JJ, Teo BS, Xie Z, Zhang Z, Xu J
Journal of ethnopharmacology 2023 May 10;307:116243
Journal of ethnopharmacology 2023 May 10;307:116243
Mitochondria-Targeted Nanosystem Enhances Radio-Radiodynamic-Chemodynamic Therapy on Triple Negative Breast Cancer.
Li J, You Z, Zhai S, Zhao J, Lu K
ACS applied materials & interfaces 2023 May 10;15(18):21941-21952
ACS applied materials & interfaces 2023 May 10;15(18):21941-21952
JNK-JUN-NCOA4 axis contributes to chondrocyte ferroptosis and aggravates osteoarthritis via ferritinophagy.
Sun K, Hou L, Guo Z, Wang G, Guo J, Xu J, Zhang X, Guo F
Free radical biology & medicine 2023 May 1;200:87-101
Free radical biology & medicine 2023 May 1;200:87-101
A novel candidate gene CLN8 regulates fat deposition in avian.
Li X, Zhang F, Sun Y, Sun D, Yang F, Liu Y, Hou Z
Journal of animal science and biotechnology 2023 May 1;14(1):70
Journal of animal science and biotechnology 2023 May 1;14(1):70
The circadian rhythm gene Bmal1 ameliorates acute deoxynivalenol-induced liver damage.
Yang LN, Xu S, Tang M, Zhou X, Liao Y, Nüssler AK, Liu L, Yang W
Archives of toxicology 2023 Mar;97(3):787-804
Archives of toxicology 2023 Mar;97(3):787-804
Danlou tablet inhibits high-glucose-induced cardiomyocyte apoptosis via the miR-34a-SIRT1 axis.
Chen R, Chen H, Yang Z, Zhu L, Bei Y, Chen W, Qiu Y
Heliyon 2023 Mar;9(3):e14479
Heliyon 2023 Mar;9(3):e14479
Electroacupuncture alleviates early brain injury via modulating microglia polarization and suppressing neuroinflammation in a rat model of subarachnoid hemorrhage.
Wang Y, Yang X, Cao Y, Li X, Xu R, Yan J, Guo Z, Sun S, Sun X, Wu Y
Heliyon 2023 Mar;9(3):e14475
Heliyon 2023 Mar;9(3):e14475
Farnesoid X Receptor (FXR) Regulates mTORC1 Signaling and Autophagy by Inhibiting SESN2 Expression.
Wang G, Chen L, Qin S, Geng H, Xia C, Zheng Y, Lei X, Zhang J, Wu S, Yao J, Deng L
Molecular nutrition & food research 2023 Mar;67(6):e2200517
Molecular nutrition & food research 2023 Mar;67(6):e2200517
Regulation of telomere silencing by the core histones-autophagy-Sir2 axis.
Mei Q, Yu Q, Li X, Chen J, Yu X
Life science alliance 2023 Mar;6(3)
Life science alliance 2023 Mar;6(3)
Trans-gnetin H isolated from the seeds of Paeonia species induces autophagy via inhibiting mTORC1 signalling through AMPK activation.
Xia C, Wang G, Chen L, Geng H, Yao J, Bai Z, Deng L
Cell proliferation 2023 Mar;56(3):e13360
Cell proliferation 2023 Mar;56(3):e13360
Myricetin improves apoptosis after ischemic stroke via inhibiting MAPK-ERK pathway.
Zhang L, Zhou T, Ji Q, He L, Lan Y, Ding L, Li L, Wang Z
Molecular biology reports 2023 Mar;50(3):2545-2557
Molecular biology reports 2023 Mar;50(3):2545-2557
Progressive degeneration of the retina in Loxl3 mutant mouse model of Stickler syndrome.
Liu Z, Mo F, Dong X, Chen G, Gao J, Zhang J
Developmental biology 2023 Mar;495:54-62
Developmental biology 2023 Mar;495:54-62
TGF-β Signaling Activation Confers Anlotinib Resistance in Gastric Cancer.
Chen J, Hai Y, Hu Q, Chen C, Jiang X, Gao Y
Pharmaceutical research 2023 Mar;40(3):689-699
Pharmaceutical research 2023 Mar;40(3):689-699
BNIP3-mediated autophagy via the mTOR/ULK1 pathway induces primordial follicle loss after ovarian tissue transplantation.
Liu F, Li M
Journal of assisted reproduction and genetics 2023 Mar;40(3):491-508
Journal of assisted reproduction and genetics 2023 Mar;40(3):491-508
PbO nanoparticles increase the expression of ICAM-1 and VCAM-1 by increasing reactive oxygen species production in choroid plexus.
Wang W, Li S, Wang X, Wang J, Zhang Y
Environmental science and pollution research international 2023 Mar;30(14):40162-40173
Environmental science and pollution research international 2023 Mar;30(14):40162-40173
The role of selenoprotein M in nickel-induced pyroptosis in mice spleen tissue via oxidative stress.
Ma W, Liu Y, Xu L, Gai X, Sun Y, Qiao S, Liu P, Liu Q, Zhang Z
Environmental science and pollution research international 2023 Mar;30(12):34270-34281
Environmental science and pollution research international 2023 Mar;30(12):34270-34281
The Rab GTPase-binding protein EHBP1L1 and its interactors CD2AP/CIN85 negatively regulate the length of primary cilia via actin remodeling.
Iwano T, Sobajima T, Takeda S, Harada A, Yoshimura SI
The Journal of biological chemistry 2023 Mar;299(3):102985
The Journal of biological chemistry 2023 Mar;299(3):102985
The well-developed actin cytoskeleton and Cthrc1 expression by actin-binding protein drebrin in myofibroblasts promote cardiac and hepatic fibrosis.
Hironaka T, Takizawa N, Yamauchi Y, Horii Y, Nakaya M
The Journal of biological chemistry 2023 Mar;299(3):102934
The Journal of biological chemistry 2023 Mar;299(3):102934
Zebrafish Galectin 3 binding protein is the target antigen of the microglial 4C4 monoclonal antibody.
Rovira M, Miserocchi M, Montanari A, Hammou L, Chomette L, Pozo J, Imbault V, Bisteau X, Wittamer V
Developmental dynamics : an official publication of the American Association of Anatomists 2023 Mar;252(3):400-414
Developmental dynamics : an official publication of the American Association of Anatomists 2023 Mar;252(3):400-414
LncRNA FRMD6-AS1 promotes hepatocellular carcinoma cell migration and stemness by regulating SENP1/HIF-1α axis.
Sun W, Lei X, Lu Q, Wu Q, Ma Q, Huang D, Zhang Y
Pathology, research and practice 2023 Mar;243:154377
Pathology, research and practice 2023 Mar;243:154377
Decreased AGGF1 facilitates the progression of placenta accreta spectrum via mediating the P53 signaling pathway under the regulation of miR-1296-5p.
Wang R, Zhao J, Liu C, Li S, Liu W, Cao Q
Reproductive biology 2023 Mar;23(1):100735
Reproductive biology 2023 Mar;23(1):100735
CEMIP promotes small cell lung cancer proliferation by activation of glutamine metabolism via FBXW7/c-Myc-dependent axis.
Mo X, Shen X, Mo X, Yu F, Tan W, Deng Z, He J, Luo Z, Chen Z, Yang J
Biochemical pharmacology 2023 Mar;209:115446
Biochemical pharmacology 2023 Mar;209:115446
Sirt3-dependent regulation of mitochondrial oxidative stress and apoptosis contributes to the dysfunction of pancreatic islets after severe burns.
Liu X, Xie X, Li D, Liu Z, Zhang B, Zang Y, Yuan H, Shen C
Free radical biology & medicine 2023 Mar;198:59-67
Free radical biology & medicine 2023 Mar;198:59-67
Porcine reproductive and respiratory syndrome virus infection triggers autophagy via ER stress-induced calcium signaling to facilitate virus replication.
Diao F, Jiang C, Sun Y, Gao Y, Bai J, Nauwynck H, Wang X, Yang Y, Jiang P, Liu X
PLoS pathogens 2023 Mar;19(3):e1011295
PLoS pathogens 2023 Mar;19(3):e1011295
Neuroprotective effects of neural stem cells pretreated with neuregulin1β on PC12 cells exposed to oxygen-glucose deprivation/reoxygenation.
Zhai QY, Ye YH, Ren YQ, Song ZH, Ge KL, Cheng BH, Guo YL
Neural regeneration research 2023 Mar;18(3):618-625
Neural regeneration research 2023 Mar;18(3):618-625
Myocardial ischemia-reperfusion injury is probably due to the excessive production of mitochondrial ROS caused by the activation of 5-HT degradation system mediated by PAF receptor.
Jin J, Xu F, Zhang Y, Guan J, Fu J
Molecular immunology 2023 Mar;155:27-43
Molecular immunology 2023 Mar;155:27-43
LncRNA UCA1 promoted cisplatin resistance in lung adenocarcinoma with HO1 targets NRF2/HO1 pathway.
Shi W, Ling L, Li C, Wu R, Zhang M, Shao F, Wang Y
Journal of cancer research and clinical oncology 2023 Mar;149(3):1295-1311
Journal of cancer research and clinical oncology 2023 Mar;149(3):1295-1311
Immunity-related long noncoding RNA WDFY3-AS2 inhibited cell proliferation and metastasis through Wnt/β-catenin signaling in oral squamous cell carcinoma.
Lin X, Ding JM, Zheng XZ, Chen JG
Archives of oral biology 2023 Mar;147:105625
Archives of oral biology 2023 Mar;147:105625
Decreasing GDF15 Promotes Inflammatory Signals and Neutrophil Infiltration in Psoriasis Models.
Zhang J, He L, Wang Z, Shao S, Qiao P, Zhang J, Zhang K, Li C, Zhang Y, Wang G, Li M
The Journal of investigative dermatology 2023 Mar;143(3):419-430.e8
The Journal of investigative dermatology 2023 Mar;143(3):419-430.e8
Neuroprotective effect of a Keap1-Nrf2 Protein-Protein Inter-action inhibitor on cerebral Ischemia/Reperfusion injury.
Qi Z, Tong Y, Luo H, Chen M, Zhou N, Chen L
Bioorganic chemistry 2023 Mar;132:106350
Bioorganic chemistry 2023 Mar;132:106350
Determination of the optimal concentration and duration of C5aR antagonist application in an inflammatory model of human dental pulp cells.
Hu J, Tan X, Wei X, Hu W, Gao L, Cao X, Yang H, Jiang Z, Li N, Teng L, Liu M
FEBS open bio 2023 Mar;13(3):570-581
FEBS open bio 2023 Mar;13(3):570-581
ROS-activated MAPK/ERK pathway regulates crosstalk between Nrf2 and Hif-1α to promote IL-17D expression protecting the intestinal epithelial barrier under hyperoxia.
Wang P, Li T, Niu C, Sun S, Liu D
International immunopharmacology 2023 Mar;116:109763
International immunopharmacology 2023 Mar;116:109763
Tiliroside targets TBK1 to induce ferroptosis and sensitize hepatocellular carcinoma to sorafenib.
Yang C, Lu T, Liu M, Yuan X, Li D, Zhang J, Zhou L, Xu M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Mar;111:154668
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Mar;111:154668
CHD1 deletion stabilizes HIF1α to promote angiogenesis and glycolysis in prostate cancer.
Wang YZ, Qian YC, Yang WJ, Ye LH, Guo GD, Lv W, Huan MX, Feng XY, Wang K, Yang Z, Gao Y, Li L, Chen YL
Asian journal of andrology 2023 Mar-Apr;25(2):152-157
Asian journal of andrology 2023 Mar-Apr;25(2):152-157
iPSC-based modeling of THD recapitulates disease phenotypes and reveals neuronal malformation.
Tristán-Noguero A, Fernández-Carasa I, Calatayud C, Bermejo-Casadesús C, Pons-Espinal M, Colini Baldeschi A, Campa L, Artigas F, Bortolozzi A, Domingo-Jiménez R, Ibáñez S, Pineda M, Artuch R, Raya Á, García-Cazorla À, Consiglio A
EMBO molecular medicine 2023 Mar 8;15(3):e15847
EMBO molecular medicine 2023 Mar 8;15(3):e15847
Long-term Pu-erh tea consumption improves blue light-induced depression-like behaviors.
Zhao S, Hu S, Sun K, Luo L, Zeng L
Food & function 2023 Mar 6;14(5):2313-2325
Food & function 2023 Mar 6;14(5):2313-2325
Semaglutide inhibits ischemia/reperfusion-induced cardiomyocyte apoptosis through activating PKG/PKCε/ERK1/2 pathway.
Zhu Q, Luo Y, Wen Y, Wang D, Li J, Fan Z
Biochemical and biophysical research communications 2023 Mar 5;647:1-8
Biochemical and biophysical research communications 2023 Mar 5;647:1-8
DNA replication initiation factor RECQ4 possesses a role in antagonizing DNA replication initiation.
Xu X, Chang CW, Li M, Omabe K, Le N, Chen YH, Liang F, Liu Y
Nature communications 2023 Mar 4;14(1):1233
Nature communications 2023 Mar 4;14(1):1233
Deletion of LCMR1 in alveolar type II cells induces lethal impairment of lung structure and function in adult mice.
Wang Y, Li C, Wu Z, Dai Y, Liu L, Chen L
Journal of thoracic disease 2023 Mar 31;15(3):1445-1459
Journal of thoracic disease 2023 Mar 31;15(3):1445-1459
LncRNA SLC25A21-AS1 increases the chemosensitivity and inhibits the progression of ovarian cancer by upregulating the expression of KCNK4.
Huang K, Chen X, Geng Z, Xiong X, Cong Y, Pan X, Liu S, Ge L, Xu J, Jia X
Functional & integrative genomics 2023 Mar 30;23(2):110
Functional & integrative genomics 2023 Mar 30;23(2):110
The RNA-binding protein hnRNP F is required for the germinal center B cell response.
Huang H, Li Y, Zhang G, Ruan GX, Zhu Z, Chen W, Zou J, Zhang R, Wang J, Ouyang Y, Xu S, Ou X
Nature communications 2023 Mar 30;14(1):1731
Nature communications 2023 Mar 30;14(1):1731
The NLRP3 inflammasome recognizes alpha-2 and alpha-7.3 giardins and decreases the pathogenicity of Giardia duodenalis in mice.
Zhao P, Li J, Li X, Dong J, Wang X, Zhang N, Li S, Sun M, Zhang X, Wang Z, Liang M, Li Y, Cao L, Gong P
Parasites & vectors 2023 Mar 3;16(1):85
Parasites & vectors 2023 Mar 3;16(1):85
NPAS2 promotes aerobic glycolysis and tumor growth in prostate cancer through HIF-1A signaling.
Ma S, Chen Y, Quan P, Zhang J, Han S, Wang G, Qi R, Zhang X, Wang F, Yuan J, Yang X, Jia W, Qin W
BMC cancer 2023 Mar 28;23(1):280
BMC cancer 2023 Mar 28;23(1):280
Pseurotin A Validation as a Metastatic Castration-Resistant Prostate Cancer Recurrence-Suppressing Lead via PCSK9-LDLR Axis Modulation.
Abdelwahed KS, Siddique AB, Ebrahim HY, Qusa MH, Mudhish EA, Rad AH, Zerfaoui M, Abd Elmageed ZY, El Sayed KA
Marine drugs 2023 Mar 28;21(4)
Marine drugs 2023 Mar 28;21(4)
Cuproptosis is involved in copper-induced hepatotoxicity in chickens.
Zhong G, Li L, Li Y, Ma F, Liao J, Li Y, Zhang H, Pan J, Hu L, Tang Z
The Science of the total environment 2023 Mar 25;866:161458
The Science of the total environment 2023 Mar 25;866:161458
SP1 transcriptionally regulates UBE2N expression to promote lung adenocarcinoma progression.
Li J, Qi C, Shao S, Chen Y, Peng Z, Shen Q, Zhang Z
Molecular biomedicine 2023 Mar 25;4(1):7
Molecular biomedicine 2023 Mar 25;4(1):7
A novel feedback regulated loop of circRRM2-IGF2BP1-MYC promotes breast cancer metastasis.
Hao R, Zhang L, Si Y, Zhang P, Wang Y, Li B, Hu J, Qi Y
Cancer cell international 2023 Mar 25;23(1):54
Cancer cell international 2023 Mar 25;23(1):54
Inhibition of miR-4640-5p alleviates pulmonary hypertension in chronic obstructive pulmonary disease patients by regulating nitric oxide synthase 1.
Yang Z, Li P, Yuan Q, Wang X, Ma HH, Zhuan B
Respiratory research 2023 Mar 24;24(1):92
Respiratory research 2023 Mar 24;24(1):92
Isoginkgetin-loaded reactive oxygen species scavenging nanoparticles ameliorate intervertebral disc degeneration via enhancing autophagy in nucleus pulposus cells.
Yu H, Teng Y, Ge J, Yang M, Xie H, Wu T, Yan Q, Jia M, Zhu Q, Shen Y, Zhang L, Zou J
Journal of nanobiotechnology 2023 Mar 21;21(1):99
Journal of nanobiotechnology 2023 Mar 21;21(1):99
PPARα Inhibits Astrocyte Inflammation Activation by Restoring Autophagic Flux after Transient Brain Ischemia.
Luo D, Ye W, Chen L, Yuan X, Zhang Y, Chen C, Jin X, Zhou Y
Biomedicines 2023 Mar 21;11(3)
Biomedicines 2023 Mar 21;11(3)
PDCD6 Promotes Hepatocellular Carcinoma Cell Proliferation and Metastasis through the AKT/GSK3β/β-catenin Pathway.
Wen SY, Liu YT, Wei BY, Ma JQ, Chen YY
Biomedical and environmental sciences : BES 2023 Mar 20;36(3):241-252
Biomedical and environmental sciences : BES 2023 Mar 20;36(3):241-252
Chlorogenic acid combined with epigallocatechin-3-gallate mitigates D-galactose-induced gut aging in mice.
Wei R, Su Z, Mackenzie GG
Food & function 2023 Mar 20;14(6):2684-2697
Food & function 2023 Mar 20;14(6):2684-2697
Human umbilical cord mesenchymal stem cells conditioned medium exerts anti-tumor effects on KGN cells in a cell density-dependent manner through activation of the Hippo pathway.
Wan W, Miao Y, Niu Y, Zhu K, Ma Y, Pan M, Ma B, Wei Q
Stem cell research & therapy 2023 Mar 20;14(1):46
Stem cell research & therapy 2023 Mar 20;14(1):46
Swimming training combined with fecal microbial transplantation protects motor functions in rats with spinal cord injury by improving the intestinal system.
Ouyang S, Wang X, Chen Y, Deng L, Yang X, Hu S, Wu S
Neuroscience letters 2023 Mar 16;799:137104
Neuroscience letters 2023 Mar 16;799:137104
Possible mechanisms associated with immune escape and apoptosis on anti-hepatocellular carcinoma effect of Mu Ji Fang granules.
Zhang YB, Bao YR, Wang S, Li TJ, Tai H, Leng JP, Yang XX, Wang BC, Meng XS
World journal of gastrointestinal oncology 2023 Mar 15;15(3):504-522
World journal of gastrointestinal oncology 2023 Mar 15;15(3):504-522
Curcumin-dependent phenotypic transformation of microglia mediates resistance to pseudorabies-induced encephalitis.
Feng L, Luo G, Li Y, Zhang C, Liu Y, Liu Y, Chen H, He D, Zhu Y, Gan L
Veterinary research 2023 Mar 14;54(1):25
Veterinary research 2023 Mar 14;54(1):25
Atf4 regulates angiogenic differences between alveolar bone and long bone macrophages by regulating M1 polarization, based on single-cell RNA sequencing, RNA-seq and ATAC-seq analysis.
Gu L, Wang Z, Gu H, Wang H, Liu L, Zhang WB
Journal of translational medicine 2023 Mar 14;21(1):193
Journal of translational medicine 2023 Mar 14;21(1):193
Near-Infrared Phototheranostic Iron Pyrite Nanocrystals Simultaneously Induce Dual Cell Death Pathways via Enhanced Fenton Reactions in Triple-Negative Breast Cancer.
Zhao C, Liu Z, Chang CC, Chen YC, Zhang Q, Zhang XD, Andreou C, Pang J, Liu ZX, Wang DY, Kircher MF, Yang J
ACS nano 2023 Mar 14;17(5):4261-4278
ACS nano 2023 Mar 14;17(5):4261-4278
Supplemental Clostridium butyricum modulates lipid metabolism by reshaping the gut microbiota composition and bile acid profile in IUGR suckling piglets.
Zhang X, Yun Y, Lai Z, Ji S, Yu G, Xie Z, Zhang H, Zhong X, Wang T, Zhang L
Journal of animal science and biotechnology 2023 Mar 13;14(1):36
Journal of animal science and biotechnology 2023 Mar 13;14(1):36
Phosphoglycerate dehydrogenase activates PKM2 to phosphorylate histone H3T11 and attenuate cellular senescence.
Wu Y, Tang L, Huang H, Yu Q, Hu B, Wang G, Ge F, Yin T, Li S, Yu X
Nature communications 2023 Mar 10;14(1):1323
Nature communications 2023 Mar 10;14(1):1323
IFN-γ Facilitates Corneal Epithelial Cell Pyroptosis Through the JAK2/STAT1 Pathway in Dry Eye.
Yang X, Zuo X, Zeng H, Liao K, He D, Wang B, Yuan J
Investigative ophthalmology & visual science 2023 Mar 1;64(3):34
Investigative ophthalmology & visual science 2023 Mar 1;64(3):34
m(6)A reader HNRNPA2B1 destabilization of ATG4B regulates autophagic activity, proliferation and olaparib sensitivity in breast cancer.
Zheng R, Yu Y, Lv L, Zhang Y, Deng H, Li J, Zhang B
Experimental cell research 2023 Mar 1;424(1):113487
Experimental cell research 2023 Mar 1;424(1):113487
A network pharmacology approach and experimental validation to investigate the anticancer mechanism and potential active targets of ethanol extract of Wei-Tong-Xin against colorectal cancer through induction of apoptosis via PI3K/AKT signaling pathway.
Lin F, Zhang G, Yang X, Wang M, Wang R, Wan M, Wang J, Wu B, Yan T, Jia Y
Journal of ethnopharmacology 2023 Mar 1;303:115933
Journal of ethnopharmacology 2023 Mar 1;303:115933
Zearalenone induces oxidative stress and autophagy in goat Sertoli cells.
Liu X, Xi H, Han S, Zhang H, Hu J
Ecotoxicology and environmental safety 2023 Mar 1;252:114571
Ecotoxicology and environmental safety 2023 Mar 1;252:114571
Lysosome-related exosome secretion mediated by miR-26b / Rab31 pathway was associated with the proliferation and migration of MCF-7 cells treated with BPA.
Chen Y, Hu Z, Tang M, Huang F, Xiong Y, Ouyang D, He J, He S, Xian H, Hu D
Ecotoxicology and environmental safety 2023 Mar 1;252:114563
Ecotoxicology and environmental safety 2023 Mar 1;252:114563
A novel circular RNA circNLRP3 alleviated ricin toxin-induced TNF-α production through sponging miR-221-5p.
Chen W, Chang Y, Sun C, Xu M, Dong M, Zhao N, Wang Y, Zhang J, Xu N, Liu W
Toxicon : official journal of the International Society on Toxinology 2023 Mar 1;224:107046
Toxicon : official journal of the International Society on Toxinology 2023 Mar 1;224:107046
ROS-responsive magnesium-containing microspheres for antioxidative treatment of intervertebral disc degeneration.
Zhang T, Wang Y, Li R, Xin J, Zheng Z, Zhang X, Xiao C, Zhang S
Acta biomaterialia 2023 Mar 1;158:475-492
Acta biomaterialia 2023 Mar 1;158:475-492
25-hydroxycholesterol inhibits human papillomavirus infection in cervical epithelial cells by perturbing cytoskeletal remodeling.
Li B, Hua C, Tian P, Sha Y, Zhang L, Wang Q, Lu L, Jiang S, Sui L
Journal of medical virology 2023 Jun;95(6):e28834
Journal of medical virology 2023 Jun;95(6):e28834
Histone mRNA polyadenylation-mediated inflammation underlies various virus infections and cancers.
Guo M, Zhu J, Hu Z, Wang Q, Songyang Z, Xiong Y
Journal of medical virology 2023 Jun;95(6):e28826
Journal of medical virology 2023 Jun;95(6):e28826
HTRA1 from OVX rat osteoclasts causes detrimental effects on endplate chondrocytes through NF-κB.
Chen L, Zhong Y, Sun S, Yang Z, Hong H, Zou D, Song C, Li W, Leng H
Heliyon 2023 Jun;9(6):e17595
Heliyon 2023 Jun;9(6):e17595
AQP8 may affect glioma proliferation and growth by regulating GSK-3β phosphorylation and nuclear transport of β-catenin.
Cai Z, Shen Z, Zhao J, Zhang H, Guo Z, Xia Q, Liang H, Liu J, Tan L, Sheng H, Zhu S
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2023 Jun;83(4):333-345
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2023 Jun;83(4):333-345
miR-484 mediates oxidative stress-induced ovarian dysfunction and promotes granulosa cell apoptosis via SESN2 downregulation.
Wang X, Yang J, Li H, Mu H, Zeng L, Cai S, Su P, Li H, Zhang L, Xiang W
Redox biology 2023 Jun;62:102684
Redox biology 2023 Jun;62:102684
Targeting hexokinase 1 alleviates NLRP3-mediated inflammation in apical periodontitis: A laboratory investigation.
Qian Y, Chen D, Zhu Y, Wu J, Wang Y, Yang W
International endodontic journal 2023 Jun;56(6):734-747
International endodontic journal 2023 Jun;56(6):734-747
The role of CNPY2 in endothelial injury and inflammation during the progress of atherosclerosis.
Huang H, Tang N, Li Y, Huo Q, Chen Q, Meng Q
Journal of molecular histology 2023 Jun;54(3):195-205
Journal of molecular histology 2023 Jun;54(3):195-205
Bach1 modulates AKT3 transcription to participate in hyperglycaemia-mediated EndMT in vascular endothelial cells.
Meng Z, Shen W, Yu L, Tong F, He H, Hu Y, Wu W, Liu J
Clinical and experimental pharmacology & physiology 2023 Jun;50(6):443-452
Clinical and experimental pharmacology & physiology 2023 Jun;50(6):443-452
Effects of long-term resveratrol treatment in hypothalamic astrocyte cultures from aged rats.
Sovrani V, Bobermin LD, Santos CL, Brondani M, Gonçalves CA, Leipnitz G, Quincozes-Santos A
Molecular and cellular biochemistry 2023 Jun;478(6):1205-1216
Molecular and cellular biochemistry 2023 Jun;478(6):1205-1216
Efficacy of Danggui Buxue decoction on diabetic nephropathy-induced renal fibrosis in rats and possible mechanism.
Ye Z, Xian W, Ling GU, Zihang LI, Jingtian Z, Wenkai W, Liang Z, Mei X
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2023 Jun;43(3):507-513
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2023 Jun;43(3):507-513
Photodynamic therapy enhances the cytotoxicity of temozolomide against glioblastoma via reprogramming anaerobic glycolysis.
Li Y, Wang D, Zhang Z, Wang Y, Zhang Z, Liang Z, Liu F, Chen L
Photodiagnosis and photodynamic therapy 2023 Jun;42:103342
Photodiagnosis and photodynamic therapy 2023 Jun;42:103342
ARHGAP44 expression is associated with the metastasis of osteosarcoma and is a promising prognostic biomarker.
Hu S, Wang W
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2023 Jun;41(6):1348-1355
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2023 Jun;41(6):1348-1355
Glycoside combinations of Buyang Huanwu decoction ameliorate atherosclerosis via STAT3, HIF-1, and VEGF.
Yan F, Ding H, Sun Z, Liu J, Li J, Zhou D, Zhang W
Naunyn-Schmiedeberg's archives of pharmacology 2023 Jun;396(6):1187-1203
Naunyn-Schmiedeberg's archives of pharmacology 2023 Jun;396(6):1187-1203
Naringin regulates endoplasmic reticulum stress and mitophagy through the ATF3/PINK1 signaling axis to alleviate pulmonary fibrosis.
Wei Y, Sun L, Liu C, Li L
Naunyn-Schmiedeberg's archives of pharmacology 2023 Jun;396(6):1155-1169
Naunyn-Schmiedeberg's archives of pharmacology 2023 Jun;396(6):1155-1169
Resveratrol and Dulaglutide ameliorate adiposity and liver dysfunction in rats with diet-induced metabolic syndrome: Role of SIRT-1 / adipokines / PPARγ and IGF-1.
Shamardl HAMA, Ibrahim NA, Merzeban DH, Elamir AM, Golam RM, Elsayed AM
Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 2023 Jun;31(1):13-27
Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 2023 Jun;31(1):13-27
Combined Application of Exosomes and FPR2 Agonist LXA4 in Controlling Fetal Membrane Inflammation and Promoting Fetal Membrane Tissue Repair.
Huang X, Liao J, Feng F, Chen S, Liao E, Li D, Dai X, Dong J, Shao Y
Reproductive sciences (Thousand Oaks, Calif.) 2023 Jun;30(6):1979-1993
Reproductive sciences (Thousand Oaks, Calif.) 2023 Jun;30(6):1979-1993
Developmental growth plate cartilage formation suppressed by artificial light at night via inhibiting BMAL1-driven collagen hydroxylation.
Chen G, Tang Q, Yu S, Shen Y, Sun J, Peng J, Yin Y, Feng G, Lu X, Mei G, Zhang Y, Wan Q, Zhang L, Chen L
Cell death and differentiation 2023 Jun;30(6):1503-1516
Cell death and differentiation 2023 Jun;30(6):1503-1516
TRIM7 inhibits encephalomyocarditis virus replication by activating interferon-β signaling pathway.
Li M, Yan J, Zhu H, Guo C, Jiang X, Gao Y, Liu X, Jiang P, Bai J
Veterinary microbiology 2023 Jun;281:109729
Veterinary microbiology 2023 Jun;281:109729
The molecular mechanism of miR-96-5p in the pathogenesis and treatment of polycystic ovary syndrome.
Liu Y, Zhang S, Chen L, Huang X, Wang M, Ponikwicka-Tyszko D, Rahman NA, Wolczynski S, Yao B, Li X
Translational research : the journal of laboratory and clinical medicine 2023 Jun;256:1-13
Translational research : the journal of laboratory and clinical medicine 2023 Jun;256:1-13
Promotion of intestinal epithelial cell apoptosis by enterotoxigenic Escherichia coli via PKA-mediated inhibition of mTORC1 activation.
Zheng Y, Wang G, Li R, Geng H, Lei X, Chen L, Wu S, Yao J, Deng L
Microbes and infection 2023 Jun;25(5):105099
Microbes and infection 2023 Jun;25(5):105099
Bone microenvironment regulative hydrogels with ROS scavenging and prolonged oxygen-generating for enhancing bone repair.
Sun H, Xu J, Wang Y, Shen S, Xu X, Zhang L, Jiang Q
Bioactive materials 2023 Jun;24:477-496
Bioactive materials 2023 Jun;24:477-496
Anti-inflammatory labdane diterpenoids from the aerial parts of Leonurus japonicus.
Wei QH, Cao XX, Xu DF, Wang ST, Zhang JS, Zhang H
Phytochemistry 2023 Jun;210:113646
Phytochemistry 2023 Jun;210:113646
Jinyinqingre Oral Liquid alleviates LPS-induced acute lung injury by inhibiting the NF-κB/NLRP3/GSDMD pathway.
Wang S, Lei P, Feng Y, Jiang M, Liu Z, Shen T, Ma S, Wang L, Guo X, DU S
Chinese journal of natural medicines 2023 Jun;21(6):423-435
Chinese journal of natural medicines 2023 Jun;21(6):423-435
Toosendanin-induced apoptosis of CMT-U27 is mediated through the mitochondrial apoptotic pathway.
Yang Y, Mei C, Xian H, Zhang X, Li J, Liang ZX, Zhi Y, Ma Y, Wang HJ
Veterinary and comparative oncology 2023 Jun;21(2):315-326
Veterinary and comparative oncology 2023 Jun;21(2):315-326
Schisandrin B Improves the Hypothermic Preservation of Celsior Solution in Human Umbilical Cord Mesenchymal Stem Cells.
Zhang Y, Wang P, Jin MX, Zhou YQ, Ye L, Zhu XJ, Li HF, Zhou M, Li Y, Li S, Liang KY, Wang Y, Gao Y, Pan MX, Zhou SQ, Peng Q
Tissue engineering and regenerative medicine 2023 Jun;20(3):447-459
Tissue engineering and regenerative medicine 2023 Jun;20(3):447-459
Chromatin remodeling and nucleoskeleton synergistically control osteogenic differentiation in different matrix stiffnesses.
Xu X, Zhang H, Li Y, Liu F, Jing Z, Ren M, Chen T, Fu Y, Wu Y, Ji P, Yang S
Materials today. Bio 2023 Jun;20:100661
Materials today. Bio 2023 Jun;20:100661
Synergistic effects of combined treatment of 1,2-dichloroethane and high-dose ethanol on liver damage in mice and the related mechanisms.
Yang J, Zhang L, Wang T, Zhang J, Li M, Jin X, Tan X, Wang G, Zhao F, Jin Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jun;176:113812
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jun;176:113812
Comprehensive analysis of lncRNA-mRNA co-expression networks in HPV-driven cervical cancer reveals the pivotal function of LINC00511-PGK1 in tumorigenesis.
Xin X, Jia-Yin Y, Jun-Yang H, Rui W, Xiong-Ri K, Long-Rui D, Liu J, Jue-Yu Z
Computers in biology and medicine 2023 Jun;159:106943
Computers in biology and medicine 2023 Jun;159:106943
Alleviating experimental pulmonary hypertension via co-delivering FoxO1 stimulus and apoptosis activator to hyperproliferating pulmonary arteries.
Li B, Teng C, Yu H, Jiang X, Xing X, Jiang Q, Lin C, Zhao Z, Zhang R, He W
Acta pharmaceutica Sinica. B 2023 Jun;13(6):2369-2382
Acta pharmaceutica Sinica. B 2023 Jun;13(6):2369-2382
The role of 14-3-3 in the progression of vascular inflammation induced by lipopolysaccharide.
Tan H, Li J, Jia C, Huang H, Li L, Liao B, Long Y, Nie Y, Yu F
International immunopharmacology 2023 Jun;119:110220
International immunopharmacology 2023 Jun;119:110220
MED27 plays a tumor-promoting role in breast cancer progression by targeting KLF4.
Wang R, Yu W, Zhu T, Lin F, Hua C, Ru L, Guo P, Wan X, Xue G, Guo Z, Han S, Lv K, Zhang G, Ge H, Guo W, Xu L, Deng W
Cancer science 2023 Jun;114(6):2277-2292
Cancer science 2023 Jun;114(6):2277-2292
Deciphering the molecular mechanism of the THBS1 gene in the TNF signaling axis in glioma stem cells.
Chen L, Fang W, Chen W, Wei Y, Ding J, Li J, Lin J, Wu Q
Cellular signalling 2023 Jun;106:110656
Cellular signalling 2023 Jun;106:110656
Visceral adipose tissue-directed human kallistatin gene therapy improves adipose tissue remodeling and metabolic health in obese mice.
Wu Y, Jiang Y, Guo JQ, Yang ZW, Carvalho A, Qian LL, Ji JJ, Ji ZJ, Ma GS, Yao YY
Cellular signalling 2023 Jun;106:110637
Cellular signalling 2023 Jun;106:110637
Targeting lncRNA DDIT4-AS1 Sensitizes Triple Negative Breast Cancer to Chemotherapy via Suppressing of Autophagy.
Jiang T, Zhu J, Jiang S, Chen Z, Xu P, Gong R, Zhong C, Cheng Y, Sun X, Yi W, Yang J, Zhou W, Cheng Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(17):e2207257
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(17):e2207257
Role of FLCN Phosphorylation in Insulin-Mediated mTORC1 Activation and Tumorigenesis.
Wang G, Chen L, Lei X, Qin S, Geng H, Zheng Y, Xia C, Yao J, Meng T, Deng L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(17):e2206826
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(17):e2206826
ERK Inhibition Promotes Engraftment of Allografts by Reprogramming T-Cell Metabolism.
Tan X, Qi C, Zhao X, Sun L, Wu M, Sun W, Gu L, Wang F, Feng H, Huang X, Xie B, Shi Z, Xie P, Wu M, Zhang Y, Chen G
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(16):e2206768
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(16):e2206768
Autonomous metal-organic framework nanorobots for active mitochondria-targeted cancer therapy.
Peng X, Tang S, Tang D, Zhou D, Li Y, Chen Q, Wan F, Lukas H, Han H, Zhang X, Gao W, Wu S
Science advances 2023 Jun 9;9(23):eadh1736
Science advances 2023 Jun 9;9(23):eadh1736
Construction and Characterization of Immortalized Fibroblast Cell Line from Bactrian Camel.
Yan M, Yong F, Ji W, Zhang L, Zhao S, Gao Y
Life (Basel, Switzerland) 2023 Jun 7;13(6)
Life (Basel, Switzerland) 2023 Jun 7;13(6)
MiR-145 regulates steroidogenesis in mouse primary granulosa cells by targeting Arpc5 and subsequent cytoskeleton remodeling.
Ma L, Wang S, Yang J, Tang W, Wu Z, Cao L, Luo A, Fu F, Yang S, Wang S
The Journal of reproduction and development 2023 Jun 6;69(3):154-162
The Journal of reproduction and development 2023 Jun 6;69(3):154-162
Potential Mechanisms of Metformin-Induced Apoptosis in HeLa Cells.
Chu Z, Tan Y, Xu C, Zhangsun D, Zhu X
Biomolecules 2023 Jun 6;13(6)
Biomolecules 2023 Jun 6;13(6)
Platycodin D suppresses proliferation, migration, and invasion of human glioblastoma cells through regulation of Skp2.
Li H, Ouyang J, Liu R
European journal of pharmacology 2023 Jun 5;948:175697
European journal of pharmacology 2023 Jun 5;948:175697
Exercise reduces hyperlipidemia-induced cardiac damage in apolipoprotein E-deficient mice via its effects against inflammation and oxidative stress.
Pei Z, Ji J, Gao Y, Wang H, Wu Y, Yang J, Yang Q, Zhang L
Scientific reports 2023 Jun 5;13(1):9134
Scientific reports 2023 Jun 5;13(1):9134
The p23 co-chaperone is a succinate-activated COX-2 transcription factor in lung adenocarcinoma tumorigenesis.
Yu Z, Peng Y, Gao J, Zhou M, Shi L, Zhao F, Wang C, Tian X, Feng L, Huo X, Zhang B, Liu M, Fang D, Ma X
Science advances 2023 Jun 30;9(26):eade0387
Science advances 2023 Jun 30;9(26):eade0387
Silencing of AJAP1 expression by promoter methylation activates the Wnt/β-catenin signaling pathway to promote tumor proliferation and metastasis in salivary adenoid cystic carcinoma.
Jiang L, Liu Y, Pan Y, Tan Z, Wang J, Zheng G, Qian C, Xu S, Zhu X, Ma W, Guerrini S, Infante-Cossio P, Wu J, Ge M, Cai X
Gland surgery 2023 Jun 30;12(6):834-852
Gland surgery 2023 Jun 30;12(6):834-852
Mechanism of Yiqi Huoxue Huatan recipe in the treatment of coronary atherosclerotic disease through network pharmacology and experiments.
Huang HT, Lv WQ, Xu FY, Wang XL, Yao YL, Su LJ, Zhao HJ, Huang Y
Medicine 2023 Jun 30;102(26):e34178
Medicine 2023 Jun 30;102(26):e34178
TMEM41B Is an Interferon-Stimulated Gene That Promotes Pseudorabies Virus Replication.
Li XQ, Zeng L, Liang DG, Qi YL, Yang GY, Zhong K, Chu BB, Wang J
Journal of virology 2023 Jun 29;97(6):e0041223
Journal of virology 2023 Jun 29;97(6):e0041223
Peptidomics Analysis Reveals the Buccal Gland of Jawless Vertebrate Lamprey as a Source of Multiple Bioactive Peptides.
Wang Y, Sun F, Wang Z, Duan X, Li Q, Pang Y, Gou M
Marine drugs 2023 Jun 29;21(7)
Marine drugs 2023 Jun 29;21(7)
Annao Pingchong decoction alleviate the neurological impairment by attenuating neuroinflammation and apoptosis in intracerebral hemorrhage rats.
Guo C, Zhou X, Wang X, Wang H, Liu J, Wang J, Lin X, Lei S, Yang Y, Liu K, Long H, Zhou D
Journal of ethnopharmacology 2023 Jun 28;310:116298
Journal of ethnopharmacology 2023 Jun 28;310:116298
Alr Gene in Brucella suis S2: Its Role in Lipopolysaccharide Biosynthesis and Bacterial Virulence in RAW264.7.
Hao M, Wang M, Zhao D, Shi Y, Yuan Y, Li J, Zhai Y, Liu X, Zhou D, Chen H, Lin P, Tang K, Liu W, Jin Y, Wang A
International journal of molecular sciences 2023 Jun 28;24(13)
International journal of molecular sciences 2023 Jun 28;24(13)
LCK facilitates DNA damage repair by stabilizing RAD51 and BRCA1 in the nucleus of chemoresistant ovarian cancer.
Dey G, Bharti R, Braley C, Alluri R, Esakov E, Crean-Tate K, McCrae K, Joehlin-Price A, Rose PG, Lathia J, Gong Z, Reizes O
Journal of ovarian research 2023 Jun 27;16(1):122
Journal of ovarian research 2023 Jun 27;16(1):122
EZH2 Gene Knockdown Inhibits Sheep Pituitary Cell Proliferation via Downregulating the AKT/ERK Signaling Pathway.
Cai Y, Chen P, Xu H, Li S, Zhao B, Fan Y, Wang F, Zhang Y
International journal of molecular sciences 2023 Jun 26;24(13)
International journal of molecular sciences 2023 Jun 26;24(13)
Protective Effect and Mechanisms of Eckol on Chronic Ulcerative Colitis Induced by Dextran Sulfate Sodium in Mice.
Liao M, Wei S, Hu X, Liu J, Wang J
Marine drugs 2023 Jun 25;21(7)
Marine drugs 2023 Jun 25;21(7)
The Cytotoxic Cardiac Glycoside (-)-Cryptanoside A from the Stems of Cryptolepis dubia and Its Molecular Targets.
Ren Y, Kaweesa EN, Tian L, Wu S, Sydara K, Xayvue M, Moore CE, Soejarto DD, Cheng X, Yu J, Burdette JE, Kinghorn AD
Journal of natural products 2023 Jun 23;86(6):1411-1419
Journal of natural products 2023 Jun 23;86(6):1411-1419
Persistent Coxsackievirus B3 Infection in Pancreatic Ductal Cells In Vitro Downregulates Cellular Polyamine Metabolism.
Mastrodomenico V, LoMascolo NJ, Firpo MR, Villanueva Guzman MDM, Zaporowski A, Mounce BC
mSphere 2023 Jun 22;8(3):e0003623
mSphere 2023 Jun 22;8(3):e0003623
Bis-Benzylisoquinoline Alkaloids Inhibit Porcine Epidemic Diarrhea Virus by Disrupting Virus Entry.
Zhang C, Chen H, Sun L, Zhao P, Qi C, Yang Y, Si A, Qian Y, Jung YS
Pathogens (Basel, Switzerland) 2023 Jun 19;12(6)
Pathogens (Basel, Switzerland) 2023 Jun 19;12(6)
Supplementing a specific synbiotic suppressed the incidence of AOM/DSS-induced colorectal cancer in mice.
Wu H, Wu Z, Qiu Y, Zhao F, Liao M, Zhong Z, Chen J, Zeng Y, Liu R
iScience 2023 Jun 16;26(6):106979
iScience 2023 Jun 16;26(6):106979
SETD7 promotes lateral plate mesoderm formation by modulating the Wnt/β-catenin signaling pathway.
Wang D, Li Y, Xu C, Wang H, Huang X, Jin X, Ren S, Gao J, Tong J, Liu J, Zhou J, Shi L
iScience 2023 Jun 16;26(6):106917
iScience 2023 Jun 16;26(6):106917
Mettl3-mediated m(6)A modification plays a role in lipid metabolism disorders and progressive liver damage in mice by regulating lipid metabolism-related gene expression.
Dai G, Huang S, Li Y, Tu X, Xia J, Zhou Z, Chen W, Zhang A, Lin J, Li Y, He D, Lin T, Cong J, Lei Y, Han L, Yao Z, Liu W, Zhou Y, Li Q, Li J, Zhang Y, Wu A, Xiao D, Wang W, Zhao W, Jia J, Lin X
Aging 2023 Jun 16;15(12):5550-5568
Aging 2023 Jun 16;15(12):5550-5568
Necroptosis-Related Prognostic Model for Pancreatic Carcinoma Reveals Its Invasion and Metastasis Potential through Hybrid EMT and Immune Escape.
Liu H, Li Z, Zhang L, Zhang M, Liu S, Wang J, Yang C, Peng Q, Du C, Jiang N
Biomedicines 2023 Jun 16;11(6)
Biomedicines 2023 Jun 16;11(6)
Endothelial progenitor cell-derived exosomes inhibit pulmonary artery smooth muscle cell in vitro proliferation and resistance to apoptosis by modulating the Mitofusin-2 and Ras-Raf-ERK1/2 signaling pathway.
Liu P, Gao S, Li Z, Pan S, Luo G, Ji Z
European journal of pharmacology 2023 Jun 15;949:175725
European journal of pharmacology 2023 Jun 15;949:175725
Kinsenoside alleviates oxidative stress-induced blood-brain barrier dysfunction via promoting Nrf2/HO-1 pathway in ischemic stroke.
Qiao N, An Z, Fu Z, Chen X, Tong Q, Zhang Y, Ren H
European journal of pharmacology 2023 Jun 15;949:175717
European journal of pharmacology 2023 Jun 15;949:175717
Comparative analysis of two new zebrafish models: The cyp1a low-expression line and cyp1a knockout line under PAHs exposure.
Xie S, Feng Y, Zhou A, Lu Z, JixingZou
Gene 2023 Jun 15;869:147391
Gene 2023 Jun 15;869:147391
Gut Microbiota Taxon-Dependent Transformation of Microglial M1/M2 Phenotypes Underlying Mechanisms of Spatial Learning and Memory Impairment after Chronic Methamphetamine Exposure.
Wu Y, Dong Z, Jiang X, Qu L, Zhou W, Sun X, Hou J, Xu H, Cheng M
Microbiology spectrum 2023 Jun 15;11(3):e0030223
Microbiology spectrum 2023 Jun 15;11(3):e0030223
Diosmetin Maintains Barrier Integrity by Reducing the Expression of ABCG2 in Colonic Epithelial Cells.
Liu J, Fu L, Yin F, Yin L, Song X, Guo H, Liu J
Journal of agricultural and food chemistry 2023 Jun 14;71(23):8931-8940
Journal of agricultural and food chemistry 2023 Jun 14;71(23):8931-8940
miR-342-5p downstream to Notch enhances arterialization of endothelial cells in response to shear stress by repressing MYC.
Zhang X, Sun J, Zhang P, Wen T, Wang R, Liang L, Yang Z, Li J, Zhang J, Che B, Feng X, Liu X, Han H, Yan X
Molecular therapy. Nucleic acids 2023 Jun 13;32:343-358
Molecular therapy. Nucleic acids 2023 Jun 13;32:343-358
Acupuncture regulates the apoptosis of ovarian granulosa cells in polycystic ovarian syndrome-related abnormal follicular development through LncMEG3-mediated inhibition of miR-21-3p.
Chen X, He H, Long B, Wei B, Yang P, Huang X, Wang Q, Lin J, Tang H
Biological research 2023 Jun 12;56(1):31
Biological research 2023 Jun 12;56(1):31
Patrinia villosa treat colorectal cancer by activating PI3K/Akt signaling pathway.
Li XC, Wang S, Yang XX, Li TJ, Gu JX, Zhao L, Bao YR, Meng XS
Journal of ethnopharmacology 2023 Jun 12;309:116264
Journal of ethnopharmacology 2023 Jun 12;309:116264
Insight into mitochondrial dysfunction mediated by clozapine-induced inhibition of PGRMC1 in PC12 cells.
Wang L, Chen Q, Ma R, Zhang B, Yang P, Cao T, Jiao S, Chen H, Lin C, Cai H
Toxicology 2023 Jun 1;491:153515
Toxicology 2023 Jun 1;491:153515
Role of SIRT5 in the analgesic effectiveness of moxibustion at ST36 in mice with inflammatory pain.
Zuo CY, Gou CY, Zhang CS, Zhou X, Lv P, Zhang HX, Fan ZP, Tian FW, Wang ZX
Heliyon 2023 Jul;9(7):e17765
Heliyon 2023 Jul;9(7):e17765
Extracts from Seseli mairei Wolff attenuate imiquimod-induced psoriasis-like inflammation by inhibiting Th17 cells.
Wang M, Yin X, Zeng Y, Hu C, Xue Y, Fang Q, Qiao X, Zhao X, Du C, Huang F, Lin Y
Heliyon 2023 Jul;9(7):e17315
Heliyon 2023 Jul;9(7):e17315
Staphylococci planktonic and biofilm environments differentially affect osteoclast formation.
Seebach E, Kraus FV, Elschner T, Kubatzky KF
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Jul;72(7):1465-1484
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Jul;72(7):1465-1484
Karyopherin Subunit Alpha 1 Enhances the Malignant Behaviors of Colon Cancer Cells via Promoting Nuclear Factor-κB p65 Nuclear Translocation.
Zhao L, Wu D, Qu Q, Li Z, Yin H
Digestive diseases and sciences 2023 Jul;68(7):3018-3031
Digestive diseases and sciences 2023 Jul;68(7):3018-3031
Targeting the mitochondrial calcium uniporter inhibits cancer progression and alleviates cisplatin resistance in esophageal squamous cell carcinoma.
Miao Y, Wang X, Lai Y, Huang Y, Yin H, Meng X, Liu H, Hou R, Lin W, Zhang X, Zhang X, Chai BC, Zhang F, Guo L, Yang S
International journal of oncology 2023 Jul;63(1)
International journal of oncology 2023 Jul;63(1)
Lipophagy-mediated cholesterol synthesis inhibition is required for the survival of hepatocellular carcinoma under glutamine deprivation.
Kong Y, Wu M, Wan X, Sun M, Zhang Y, Wu Z, Li C, Liang X, Gao L, Ma C, Yue X
Redox biology 2023 Jul;63:102732
Redox biology 2023 Jul;63:102732
Ubiquitin ligase MARCH8 promotes the malignant progression of hepatocellular carcinoma through PTEN ubiquitination and degradation.
Xu Y, Zhang D, Ji J, Zhang L
Molecular carcinogenesis 2023 Jul;62(7):1062-1072
Molecular carcinogenesis 2023 Jul;62(7):1062-1072
The histone H2B ubiquitination regulator Wac is essential for plasma cell differentiation.
Li Y, Ruan GX, Chen W, Huang H, Zhang R, Wang J, Ouyang Y, Zhu Z, Meng L, Wang R, Huo J, Xu S, Ou X
FEBS letters 2023 Jul;597(13):1748-1760
FEBS letters 2023 Jul;597(13):1748-1760
Inhibition of STEAP1 ameliorates inflammation and ferroptosis of acute lung injury caused by sepsis in LPS-induced human pulmonary microvascular endothelial cells.
Zou X, Liu C, Huang Z, Xiang S, Li K, Yuan Y, Hao Y, Zhou F
Molecular biology reports 2023 Jul;50(7):5667-5674
Molecular biology reports 2023 Jul;50(7):5667-5674
Aprepitant inhibits the progression of esophageal squamous cancer by blocking the truncated neurokinin‑1 receptor.
Zheng Y, Sang M, Liu F, Gu L, Li J, Wu Y, Shan B
Oncology reports 2023 Jul;50(1)
Oncology reports 2023 Jul;50(1)
Venoarterial extracorporeal membrane oxygenation improves survival in a rat model of acute myocardial infarction.
Wei S, Cheng X, Li J, Zhai K, Huang J, Wang S, Li Y, Liu D
Artificial organs 2023 Jul;47(7):1163-1173
Artificial organs 2023 Jul;47(7):1163-1173
Ginseng saponin metabolite 20(S)-protopanaxadiol relieves pulmonary fibrosis by multiple-targets signaling pathways.
Ren G, Lv W, Ding Y, Wang L, Cui Z, Li R, Tian J, Zhang C
Journal of ginseng research 2023 Jul;47(4):543-551
Journal of ginseng research 2023 Jul;47(4):543-551
Proteasomal inhibitors induce myeloma cell pyroptosis via the BAX/GSDME pathway.
Liang JP, He YM, Cui YL, Sun YN, He GS, Zhu ZG, Mao XL
Acta pharmacologica Sinica 2023 Jul;44(7):1464-1474
Acta pharmacologica Sinica 2023 Jul;44(7):1464-1474
PM(2.5) induces autophagy-dependent ferroptosis by endoplasmic reticulum stress in SH-SY5Y cells.
Guo CC, Xu ZM, Lyu Y, Li XH, Li ZF, He H, Tian FJ, Zheng JP
Journal of applied toxicology : JAT 2023 Jul;43(7):1013-1025
Journal of applied toxicology : JAT 2023 Jul;43(7):1013-1025
Carnitine o-octanoyltransferase is a p53 target that promotes oxidative metabolism and cell survival following nutrient starvation.
Sanford JD, Franklin D, Grois GA, Jin A, Zhang Y
The Journal of biological chemistry 2023 Jul;299(7):104908
The Journal of biological chemistry 2023 Jul;299(7):104908
MAP2 caps tau fibrils and inhibits aggregation.
Holden MR, Krzesinski BJ, Weismiller HA, Shady JR, Margittai M
The Journal of biological chemistry 2023 Jul;299(7):104891
The Journal of biological chemistry 2023 Jul;299(7):104891
Hydrogen sulfide attenuates TMAO‑induced macrophage inflammation through increased SIRT1 sulfhydration.
Liu MH, Lin XL, Xiao LL
Molecular medicine reports 2023 Jul;28(1)
Molecular medicine reports 2023 Jul;28(1)
Dach1 deficiency drives alveolar epithelium apoptosis in pulmonary fibrosis via modulating C-Jun/Bim activity.
Lu Y, Tang K, Wang S, Tian Z, Fan Y, Li B, Wang M, Zhao J, Xie J
Translational research : the journal of laboratory and clinical medicine 2023 Jul;257:54-65
Translational research : the journal of laboratory and clinical medicine 2023 Jul;257:54-65
Activation of pyroptosis by specific organelle-targeting photodynamic therapy to amplify immunogenic cell death for anti-tumor immunotherapy.
Zeng S, Chen C, Zhang L, Liu X, Qian M, Cui H, Wang J, Chen Q, Peng X
Bioactive materials 2023 Jul;25:580-593
Bioactive materials 2023 Jul;25:580-593
SIRT3-mediated autophagy contributes to ferroptosis-induced anticancer by inducing the formation of BECN1-SLC7A11 complex.
Huang P, Zhao H, Pan X, Li J, Pan W, Dai H, Wang J, Xia C, Liu F
Biochemical pharmacology 2023 Jul;213:115592
Biochemical pharmacology 2023 Jul;213:115592
Circular RNA circ-TNRC6B inhibits the proliferation and invasion of esophageal squamous cell carcinoma cells by regulating the miR-452-5p/DAG1 axis.
Xu R, Ding P, Zhao X, Li Z, Liu F, Gu L, Zheng Y, Sang M, Meng L
Molecular oncology 2023 Jul;17(7):1437-1452
Molecular oncology 2023 Jul;17(7):1437-1452
Ceftriaxone improves impairments in synaptic plasticity and cognitive behavior in APP/PS1 mouse model of Alzheimer's disease by inhibiting extrasynaptic NMDAR-STEP(61) signaling.
He RB, Li L, Liu LZ, Ma YJ, Fan SJ, Liu LR, Li WB, Xian XH
Journal of neurochemistry 2023 Jul;166(2):215-232
Journal of neurochemistry 2023 Jul;166(2):215-232
Engineered Salmonella inhibits GPX4 expression and induces ferroptosis to suppress glioma growth in vitro and in vivo.
Chen J, Li T, Zhou N, He Y, Zhong J, Ma C, Zeng M, Ji J, Huang JD, Ke Y, Sun H
Journal of neuro-oncology 2023 Jul;163(3):607-622
Journal of neuro-oncology 2023 Jul;163(3):607-622
Diagnostic value and underlying mechanism of nasal nitric oxide in eosinophilic chronic rhinosinusitis with nasal polyps.
Tang B, Tu J, Zhang M, Zhang Z, Yu J, Shen L, Luo Q, Ye J
Molecular immunology 2023 Jul;159:1-14
Molecular immunology 2023 Jul;159:1-14
Effects of chronic sleep restriction on the neuro-phenotypes of Ctnnd2 knockout mice.
Xu M, Wang X, Wang L, Wang S, Deng J, Wang Y, Li Y, Pan S, Liao A, Tao Y, Tan S
Brain and behavior 2023 Jul;13(7):e3075
Brain and behavior 2023 Jul;13(7):e3075
Glucocorticoids improve the balance of M1/M2 macrophage polarization in experimental autoimmune uveitis through the P38MAPK-MEF2C axis.
Qu R, Zhou M, Qiu Y, Peng Y, Yin X, Liu B, Bi H, Gao Y, Guo D
International immunopharmacology 2023 Jul;120:110392
International immunopharmacology 2023 Jul;120:110392
Ginkgo biloba extract attenuates cisplatin-induced renal interstitial fibrosis by inhibiting the activation of renal fibroblasts through down-regulating the HIF-1α/STAT3/IL-6 pathway in renal tubular epithelial cells.
Zhang Y, Qin X, Yang Y, Li J, Li X, Zou X, Huang Z, Huang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul;115:154809
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul;115:154809
Cannabidiol alleviates neuroinflammation and attenuates neuropathic pain via targeting FKBP5.
Wang X, Lin C, Jin S, Wang Y, Peng Y, Wang X
Brain, behavior, and immunity 2023 Jul;111:365-375
Brain, behavior, and immunity 2023 Jul;111:365-375
A Bioinspired Manganese-Organic Framework Ameliorates Ischemic Stroke through its Intrinsic Nanozyme Activity and Upregulating Endogenous Antioxidant Enzymes.
Wang J, Wang Y, Xiaohalati X, Su Q, Liu J, Cai B, Yang W, Wang Z, Wang L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jul;10(20):e2206854
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jul;10(20):e2206854
Potential effects of brain lipid binding protein in the pathogenesis of amyotrophic lateral sclerosis.
Zhou Q, Kang Q, Chen W, Xu R
Science progress 2023 Jul-Sep;106(3):368504231184320
Science progress 2023 Jul-Sep;106(3):368504231184320
USP51 promotes non-small cell lung carcinoma cell stemness by deubiquitinating TWIST1.
Chen J, Wu Z, Deng W, Tang M, Wu L, Lin N, Chen L, Fu Y, Zhao M, Chen C, Li W
Journal of translational medicine 2023 Jul 8;21(1):453
Journal of translational medicine 2023 Jul 8;21(1):453
Transcription Factor Nrf2 Modulates Lipopolysaccharide-Induced Injury in Bovine Endometrial Epithelial Cells.
Song P, Liu C, Sun M, Liu J, Lin P, Chen H, Zhou D, Tang K, Wang A, Jin Y
International journal of molecular sciences 2023 Jul 7;24(13)
International journal of molecular sciences 2023 Jul 7;24(13)
Higher expression of pseudouridine synthase 7 promotes non-small cell lung cancer progression and suggests a poor prognosis.
Zhang G, Zhu Y, Tan Y, Chen B, Shan S, Zhang G, Lu J
Journal of cardiothoracic surgery 2023 Jul 7;18(1):222
Journal of cardiothoracic surgery 2023 Jul 7;18(1):222
Polyphyllin D punctures hypertrophic lysosomes to reverse drug resistance of hepatocellular carcinoma by targeting acid sphingomyelinase.
Wang Y, Chen YY, Gao GB, Zheng YH, Yu NN, Ouyang L, Gao X, Li N, Wen SY, Huang S, Zhao Q, Liu L, Cao M, Zhang S, Zhang J, He QY
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Jul 5;31(7):2169-2187
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Jul 5;31(7):2169-2187
CircGNB1 facilitates the malignant phenotype of GSCs by regulating miR-515-5p/miR-582-3p-XPR1 axis.
Hu J, Zhang G, Wang Y, Xu K, Chen L, Luo G, Xu J, Li H, Pei D, Zhao X, Guo Z, Li X, Zong S, Jiang Y, Jing Z
Cancer cell international 2023 Jul 5;23(1):132
Cancer cell international 2023 Jul 5;23(1):132
KRT17 Promotes T-lymphocyte Infiltration Through the YTHDF2-CXCL10 Axis in Colorectal Cancer.
Liang W, Liu H, Zeng Z, Liang Z, Xie H, Li W, Xiong L, Liu Z, Chen M, Jie H, Zheng X, Huang L, Kang L
Cancer immunology research 2023 Jul 5;11(7):875-894
Cancer immunology research 2023 Jul 5;11(7):875-894
The promoting effect and mechanism of Nrf2 on cell metastasis in cervical cancer.
Zhang M, Hong X, Ma N, Wei Z, Ci X, Zhang S
Journal of translational medicine 2023 Jul 4;21(1):433
Journal of translational medicine 2023 Jul 4;21(1):433
Sodium Propionate Relieves LPS-Induced Inflammation by Suppressing the NF-ĸB and MAPK Signaling Pathways in Rumen Epithelial Cells of Holstein Cows.
Zhao C, Yi F, Wei B, Tan P, Huang Y, Zeng F, Wang Y, Xu C, Wang J
Toxins 2023 Jul 3;15(7)
Toxins 2023 Jul 3;15(7)
Exosomes promote hFOB1.19 proliferation and differentiation via LINC00520.
Wu J, Zhang L, Liu H, Zhang J, Tang P
Journal of orthopaedic surgery and research 2023 Jul 29;18(1):546
Journal of orthopaedic surgery and research 2023 Jul 29;18(1):546
Oxygen-Sensing Protein Cysteamine Dioxygenase from Mandarin Fish Involved in the Arg/N-Degron Pathway and Siniperca chuatsi Rhabdovirus Infection.
Liu W, He J, Li Z, Weng S, Guo C, He J
Viruses 2023 Jul 28;15(8)
Viruses 2023 Jul 28;15(8)
Discovery of a Novel Bifunctional Steroid Analog, YXG-158, as an Androgen Receptor Degrader and CYP17A1 Inhibitor for the Treatment of Enzalutamide-Resistant Prostate Cancer.
Wang A, Luo X, Meng X, Lu Z, Chen K, Yang Y
Journal of medicinal chemistry 2023 Jul 27;66(14):9972-9991
Journal of medicinal chemistry 2023 Jul 27;66(14):9972-9991
Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice.
Lin XT, Zhang J, Liu ZY, Wu D, Fang L, Li CM, Yu HQ, Xie CM
Cell reports 2023 Jul 25;42(7):112812
Cell reports 2023 Jul 25;42(7):112812
Disruption of neuronal RHEB signaling impairs oligodendrocyte differentiation and myelination through mTORC1-DLK1 axis.
Huang H, Jing B, Zhu F, Jiang W, Tang P, Shi L, Chen H, Ren G, Xia S, Wang L, Cui Y, Yang Z, Platero AJ, Hutchins AP, Chen M, Worley PF, Xiao B
Cell reports 2023 Jul 25;42(7):112801
Cell reports 2023 Jul 25;42(7):112801
Targeting CXCR1 alleviates hyperoxia-induced lung injury through promoting glutamine metabolism.
Qin H, Zhuang W, Liu X, Wu J, Li S, Wang Y, Liu X, Chen C, Zhang H
Cell reports 2023 Jul 25;42(7):112745
Cell reports 2023 Jul 25;42(7):112745
Neobavaisoflavone induces pyroptosis of liver cancer cells via Tom20 sensing the activated ROS signal.
Li Y, Zhao R, Xiu Z, Yang X, Zhu Y, Han J, Li S, Li Y, Sun L, Li X, Jin N, Li Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154869
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154869
The microbial metabolite Urolithin A reduces C. difficile toxin expression and repairs toxin-induced epithelial damage.
Ghosh S, Erickson D, Chua MJ, Collins J, Jala VR
bioRxiv : the preprint server for biology 2023 Jul 24;
bioRxiv : the preprint server for biology 2023 Jul 24;
Mechanical force induces mitophagy-mediated anaerobic oxidation in periodontal ligament stem cells.
Zhang Z, Cui S, Fu Y, Wang J, Liu J, Wei F
Cellular & molecular biology letters 2023 Jul 21;28(1):57
Cellular & molecular biology letters 2023 Jul 21;28(1):57
Induced neural stem cells suppressed neuroinflammation by inhibiting the microglial pyroptotic pathway in intracerebral hemorrhage rats.
Liu J, Cao C, Jin Y, Wang Y, Ma X, Li J, Guo S, Yang J, Niu J, Liang X
iScience 2023 Jul 21;26(7):107022
iScience 2023 Jul 21;26(7):107022
Recombinant protein EBI3 attenuates Clonorchis sinensis-induced liver fibrosis by inhibiting hepatic stellate cell activation in mice.
Zhao L, Li J, Mo G, Cao D, Li C, Huang G, Jiang L, Chen G, Yao H, Peng X
Parasites & vectors 2023 Jul 21;16(1):246
Parasites & vectors 2023 Jul 21;16(1):246
Endoplasmic Reticulum Stress Mediated NLRP3 Inflammasome Activation and Pyroptosis in THP-1 Macrophages Infected with Bacillus Calmette-Guérin.
Nie X, Ma B, Liu L, Yuan X, Li M, Liu Y, Hou Y, Yang Y, Xu J, Wang Y
International journal of molecular sciences 2023 Jul 20;24(14)
International journal of molecular sciences 2023 Jul 20;24(14)
Quantitative Measurement of Secretory Protein Mistargeting by Proximity Labeling and Parallel Reaction Monitoring.
Lyu Z, Genereux JC
bioRxiv : the preprint server for biology 2023 Jul 20;
bioRxiv : the preprint server for biology 2023 Jul 20;
Single-cell transcriptome sequencing-based analysis: probing the mechanisms of glycoprotein NMB regulation of epithelial cells involved in silicosis.
Yang S, Sun Y, Long M, Zhou X, Yuan M, Yang L, Luo W, Cheng Y, Zhang X, Jiang W, Chao J
Particle and fibre toxicology 2023 Jul 19;20(1):29
Particle and fibre toxicology 2023 Jul 19;20(1):29
Cold exposure protects against medial arterial calcification development via autophagy.
Li FX, Liu JJ, Xu F, Shan SK, Zheng MH, Lei LM, Lin X, Guo B, Li CC, Wu F, Tang KX, Cao YC, Wu YY, Duan JY, Wu YL, He SY, Chen X, Yuan LQ
Journal of nanobiotechnology 2023 Jul 17;21(1):226
Journal of nanobiotechnology 2023 Jul 17;21(1):226
Protective effect of total flavonoids of Engelhardia roxburghiana Wall. leaves against radiation-induced intestinal injury in mice and its mechanism.
Wu S, Tian C, Tu Z, Guo J, Xu F, Qin W, Chang H, Wang Z, Hu T, Sun X, Ning H, Li Y, Gou W, Hou W
Journal of ethnopharmacology 2023 Jul 15;311:116428
Journal of ethnopharmacology 2023 Jul 15;311:116428
Mulberry leaves attenuate D-galactose-induced aging in vivo and in vitro.
Zhu Y, Han Y, Wang W, Liang G, Qi J
Journal of ethnopharmacology 2023 Jul 15;311:116286
Journal of ethnopharmacology 2023 Jul 15;311:116286
Open source board based acoustofluidic transwells for reversible disruption of the blood-brain barrier for therapeutic delivery.
Wang K, Sun C, Dumčius P, Zhang H, Liao H, Wu Z, Tian L, Peng W, Fu Y, Wei J, Cai M, Zhong Y, Li X, Yang X, Cui M
Biomaterials research 2023 Jul 15;27(1):69
Biomaterials research 2023 Jul 15;27(1):69
Recombinant humanized collagen type III with high antitumor activity inhibits breast cancer cells autophagy, proliferation, and migration through DDR1.
Liu X, Li H, Wang T, Yang T, Yang X, Guo K, Hu L, Ming J
International journal of biological macromolecules 2023 Jul 15;243:125130
International journal of biological macromolecules 2023 Jul 15;243:125130
Transcriptome-Based Identification of the Muscle Tissue-Specific Expression Gene CKM and Its Regulation of Proliferation, Apoptosis and Differentiation in Chicken Primary Myoblasts.
Chen B, Wang Y, Hou D, Zhang Y, Zhang B, Niu Y, Ji H, Tian Y, Liu X, Kang X, Cai H, Li Z
Animals : an open access journal from MDPI 2023 Jul 14;13(14)
Animals : an open access journal from MDPI 2023 Jul 14;13(14)
VprBP/DCAF1 triggers melanomagenic gene silencing through histone H2A phosphorylation.
Shin Y, Kim S, Liang G, Ulmer TS, An W
Research square 2023 Jul 12;
Research square 2023 Jul 12;
Glc7/PP1 dephosphorylates histone H3T11 to regulate autophagy and telomere silencing in response to nutrient availability.
Zhang X, Yu Q, Wu Y, Zhang Y, He Y, Wang R, Yu X, Li S
Cell discovery 2023 Jul 11;9(1):71
Cell discovery 2023 Jul 11;9(1):71
Confirmation of the predictive function of cuproptosis-related gene FDX1 in clear cell renal carcinoma using qRT-PCR and western blotting.
Cai C, Zhou K, Jing J, Ren Y, Weng G, Cen D, Wang X, Huang S
Aging 2023 Jul 10;15(13):6117-6134
Aging 2023 Jul 10;15(13):6117-6134
TATA-box-binding protein promotes hepatocellular carcinoma metastasis through epithelial-mesenchymal transition.
Cao J, Yang S, Luo T, Yang R, Zhu H, Zhao T, Jiang K, Xu B, Wang Y, Chen F
Hepatology communications 2023 Jul 1;7(7)
Hepatology communications 2023 Jul 1;7(7)
Elevated FBXL18 promotes RPS15A ubiquitination and SMAD3 activation to drive HCC.
Yu HQ, Li F, Xiong H, Fang L, Zhang J, Bie P, Xie CM
Hepatology communications 2023 Jul 1;7(7)
Hepatology communications 2023 Jul 1;7(7)
Tartary buckwheat flavonoids alleviates high-fat diet induced kidney fibrosis in mice by inhibiting MAPK and TGF-β1/Smad signaling pathway.
Liu S, Fu S, Jin Y, Geng R, Li Y, Zhang Y, Liu J, Guo W
Chemico-biological interactions 2023 Jul 1;379:110533
Chemico-biological interactions 2023 Jul 1;379:110533
Enhanced autophagy reversed aflatoxin B1-induced decrease in lactate secretion of dairy goat Sertoli cells.
Han S, Zhang H, Liu X, Wen F, Li B, Bie Z, Qiu H, Hu J
Ecotoxicology and environmental safety 2023 Jul 1;259:115063
Ecotoxicology and environmental safety 2023 Jul 1;259:115063
Microcystin‑leucine arginine promotes colorectal cancer cell proliferation by activating the PI3K/Akt/Wnt/β‑catenin pathway.
Tang Y, Yi X, Zhang X, Liu B, Lu Y, Pan Z, Yu T, Feng W
Oncology reports 2023 Jan;49(1)
Oncology reports 2023 Jan;49(1)
Ginsenoside Rg1 ameliorates chronic intermittent hypoxia-induced vascular endothelial dysfunction by suppressing the formation of mitochondrial reactive oxygen species through the calpain-1 pathway.
Zhao F, Lu M, Wang H
Journal of ginseng research 2023 Jan;47(1):144-154
Journal of ginseng research 2023 Jan;47(1):144-154
An in vivo and in vitro model on the protective effect of cilnidipine on contrast-induced nephropathy via regulation of apoptosis and CaMKⅡ/mPTP pathway.
Liu K, Hu C, Yin W, Zhou L, Gu X, Zuo X
Journal of biochemical and molecular toxicology 2023 Jan;37(1):e23238
Journal of biochemical and molecular toxicology 2023 Jan;37(1):e23238
Anti-Postmenopausal osteoporosis effects of Isopsoralen: A bioinformatics-integrated experimental study.
Li H, Wang C, Jin Y, Cai Y, Yao J, Meng Q, Wu J, Wang H, Sun H, Liu M
Phytotherapy research : PTR 2023 Jan;37(1):231-251
Phytotherapy research : PTR 2023 Jan;37(1):231-251
Silencing TRAIP suppresses cell proliferation and migration/invasion of triple negative breast cancer via RB-E2F signaling and EMT.
Zheng Y, Jia H, Wang P, Liu L, Chen Z, Xing X, Wang J, Tan X, Wang C
Cancer gene therapy 2023 Jan;30(1):74-84
Cancer gene therapy 2023 Jan;30(1):74-84
Nuclear factor Nrf2 promotes glycosidase OGG1 expression by activating the AKT pathway to enhance leukemia cell resistance to cytarabine.
Shang Q, Pan C, Zhang X, Yang T, Hu T, Zheng L, Cao S, Feng C, Hu X, Chai X, Wang J, Fang Q
The Journal of biological chemistry 2023 Jan;299(1):102798
The Journal of biological chemistry 2023 Jan;299(1):102798
Metabolomic and transcriptomic studies of improvements in myocardial infarction due to Pycr1 deletion.
Xue Z, Pan Y, Kong X, Zhang J, Wu D, Zhou B
Journal of cellular and molecular medicine 2023 Jan;27(1):89-100
Journal of cellular and molecular medicine 2023 Jan;27(1):89-100
Effect of transmembrane protein 100 on prostate cancer progression by regulating SCNN1D through the FAK/PI3K/AKT pathway.
Ye Z, Xia Y, Li L, Li B, Chen W, Han S, Zhou X, Chen L, Yu W, Ruan Y, Cheng F
Translational oncology 2023 Jan;27:101578
Translational oncology 2023 Jan;27:101578
CD166-specific CAR-T cells potently target colorectal cancer cells.
He S, Li S, Guo J, Zeng X, Liang D, Zhu Y, Li Y, Yang D, Zhao X
Translational oncology 2023 Jan;27:101575
Translational oncology 2023 Jan;27:101575
Spinal Cord Stimulation Attenuates Neural Remodeling, Inflammation, and Fibrosis After Myocardial Infarction.
He Y, Sun Z, Jiang J, Yin X, Han J, Zhang Y, Zheng L
Neuromodulation : journal of the International Neuromodulation Society 2023 Jan;26(1):57-67
Neuromodulation : journal of the International Neuromodulation Society 2023 Jan;26(1):57-67
Expression of group II metabotropic glutamate receptors in rat superior cervical ganglion.
Wei X, Zhao C, Jia X, Zhao B, Liu Y
Autonomic neuroscience : basic & clinical 2023 Jan;244:103053
Autonomic neuroscience : basic & clinical 2023 Jan;244:103053
Neuroprotective effect of histamine H3 receptor blockade on methamphetamine-induced cognitive impairment in mice.
Luo H, Li X, Fan R, Ruan Y, Qian L, Shen Y, Si Z, Li L, Liu Y
Pharmacology, biochemistry, and behavior 2023 Jan;222:173512
Pharmacology, biochemistry, and behavior 2023 Jan;222:173512
ML390 inhibits enterovirus 71 replication by targeting de novo pyrimidine biosynthesis pathway.
Yang Q, Wu C, Zhu G, Ren F, Lin B, Huang R, Hu X, Zhao D, Peng K, Wu Y, Wang Q, Huang C, Zhang D
Antiviral research 2023 Jan;209:105498
Antiviral research 2023 Jan;209:105498
Inhibition of deubiquitinase USP28 attenuates cyst growth in autosomal dominant polycystic kidney disease.
Ren Y, Zhu X, Fu K, Zhang H, Zhao W, Lin Y, Fang Q, Wang J, Chen Y, Guo D
Biochemical pharmacology 2023 Jan;207:115355
Biochemical pharmacology 2023 Jan;207:115355
Protective Mechanism of Ethyl Gallate against Intestinal Ischemia-Reperfusion Injury in Mice by in Vivo and in Vitro Studies Based on Transcriptomics.
Fan S, Feng X, Li K, Li B, Diao Y
Chemistry & biodiversity 2023 Jan;20(1):e202200643
Chemistry & biodiversity 2023 Jan;20(1):e202200643
Translational control of murine adiponectin expression by an upstream open reading frame element.
Vasu K, Ramachandiran I, Chechi A, Khan K, Khan D, Kaufman R, Fox PL
RNA biology 2023 Jan;20(1):737-749
RNA biology 2023 Jan;20(1):737-749
Critical role of caveolin-1 in intestinal ischemia reperfusion by inhibiting protein kinase C βII.
Chen Z, Wang Z, Liu D, Zhao X, Ning S, Liu X, Wang G, Zhang F, Luo F, Yao J, Tian X
Free radical biology & medicine 2023 Jan;194:62-70
Free radical biology & medicine 2023 Jan;194:62-70
Fluvoxamine alleviates bleomycin-induced lung fibrosis via regulating the cGAS-STING pathway.
Xie X, Wu X, Zhao D, Liu Y, Du Q, Li Y, Xu Y, Li Y, Qiu Y, Yang Y
Pharmacological research 2023 Jan;187:106577
Pharmacological research 2023 Jan;187:106577
Pine pollen extract alleviates ethanol-induced oxidative stress and apoptosis in HepG2 cells via MAPK signaling.
Ma D, Wang Z, He Z, Wang Z, Chen Q, Qin F, Zeng M, Chen J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jan;171:113550
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jan;171:113550
Polysaccharide-rich fractions from Enteromorpha prolifera improve hepatic steatosis and gut barrier integrity in high-fat diet-induced obese mice linking to modulation of gut microbiota.
Zou T, Xie F, Liang P, Chen J, Wang Z, Du M, You J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jan;157:114034
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jan;157:114034
Knockdown of Brg1 reduced mucus secretion in HDM stimulated airway inflammation.
Xu M, Hu J, Yang L, Gen G, Fu Z, Luo Z, Zou W
Molecular immunology 2023 Jan;153:42-50
Molecular immunology 2023 Jan;153:42-50
Multiomics analyses and machine learning of nuclear receptor coactivator 6 reveal its essential role in hepatocellular carcinoma.
Fang Y, Xu Y, Liao W, Ji T, Yu L, Li L, Pan M, Yang D
Cancer science 2023 Jan;114(1):75-90
Cancer science 2023 Jan;114(1):75-90
PLD2 deletion alleviates disruption of tight junctions in sepsis-induced ALI by regulating PA/STAT3 phosphorylation pathway.
Qian T, Qi B, Fei Y, Li J, Luo L, Lv B, Song Y, Sheng S, Xiao W, Huang X, Wang X
International immunopharmacology 2023 Jan;114:109561
International immunopharmacology 2023 Jan;114:109561
Huc-MSCs-derived exosomes attenuate neuropathic pain by inhibiting activation of the TLR2/MyD88/NF-κB signaling pathway in the spinal microglia by targeting Rsad2.
Gao X, Gao LF, Zhang YN, Kong XQ, Jia S, Meng CY
International immunopharmacology 2023 Jan;114:109505
International immunopharmacology 2023 Jan;114:109505
Methyl gallate prevents oxidative stress induced apoptosis and ECM degradation in chondrocytes via restoring Sirt3 mediated autophagy and ameliorates osteoarthritis progression.
Li Y, Shen B, Lv C, Zhu X, Naren Q, Xu D, Chen H, Wu F
International immunopharmacology 2023 Jan;114:109489
International immunopharmacology 2023 Jan;114:109489
Chinese herbal medicine alleviates the pathogenesis of polycystic ovary syndrome by improving oxidative stress and glucose metabolism via mitochondrial Sirtuin 3 signaling.
Zhang Q, Ren J, Wang F, Li M, Pan M, Zhang H, Qu F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;109:154556
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;109:154556
Yishen-Qingli-Huoxue formula attenuates renal fibrosis by inhibiting indoxyl sulfate via AhR/snai1 signaling.
Chen C, Sun S, Zhao J, Wu Q, He W, Sun W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;108:154546
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;108:154546
Involvement of Galectin-3 in neurocognitive impairment in obstructive sleep apnea via regulating inflammation and oxidative stress through NLRP3.
Zong D, Liu X, Shen C, Liu T, Ouyang R
Sleep medicine 2023 Jan;101:1-10
Sleep medicine 2023 Jan;101:1-10
Disruption of COMMD1 accelerates diabetic atherosclerosis by promoting glycolysis.
Zhang L, Li L, Li Y, Jiang H, Sun Z, Zang G, Qian Y, Shao C, Wang Z
Diabetes & vascular disease research 2023 Jan-Feb;20(1):14791641231159009
Diabetes & vascular disease research 2023 Jan-Feb;20(1):14791641231159009
Heat enhances the inhibitory effect of lipopolysaccharide on duck granulosa cell proliferation and steroid biosynthesis in vitro.
Luo P, Huang XB, Zhan XZ, Yang C, Deng ZC, Zhang C, Fu XL, Tian YB, Huang YM, Liu WJ
Animal science journal = Nihon chikusan Gakkaiho 2023 Jan-Dec;94(1):e13851
Animal science journal = Nihon chikusan Gakkaiho 2023 Jan-Dec;94(1):e13851
Caveolae-associated protein 3 promotes adipogenic differentiation of porcine preadipocytes by promoting extracellular signal-regulated kinase phosphorylation.
Shi M, Yang S, Huang X, Wang S, Li W, Yun J, Lu C, Yang Y, Cai C, Gao P, Guo X, Li B, Cao G
Animal science journal = Nihon chikusan Gakkaiho 2023 Jan-Dec;94(1):e13822
Animal science journal = Nihon chikusan Gakkaiho 2023 Jan-Dec;94(1):e13822
Cancer susceptibility 18 positively regulates NUAK Family Kinase 1 expression to promote migration and invasion via sponging of miR-5586-5p in cervical cancer cells.
Wang J, Zhang B, Gong S, Liu Y, Yi L, Long Y
International journal of immunopathology and pharmacology 2023 Jan-Dec;37:3946320231223310
International journal of immunopathology and pharmacology 2023 Jan-Dec;37:3946320231223310
Human Umbilical Cord Mesenchymal Stem Cells Improve the Status of Hypoxic/Ischemic Cerebral Palsy Rats by Downregulating NogoA/NgR/Rho Pathway.
Luo Y, Qu J, He Z, Zhang M, Zou Z, Li L, Zhang Y, Ye J
Cell transplantation 2023 Jan-Dec;32:9636897231210069
Cell transplantation 2023 Jan-Dec;32:9636897231210069
Pomegranate Peel Extract Sensitizes Hepatocellular Carcinoma Cells to Ionizing Radiation, Induces Apoptosis and Inhibits MAPK, JAK/STAT3, β-Catenin/NOTCH, and SOCS3 Signaling.
Elbakry MMM, ElBakary NM, Hagag SA, Hemida EHA
Integrative cancer therapies 2023 Jan-Dec;22:15347354221151021
Integrative cancer therapies 2023 Jan-Dec;22:15347354221151021
Dehydrocorydaline alleviates sleep deprivation-induced persistent postoperative pain in adolescent mice through inhibiting microglial P2Y(12) receptor expression in the spinal cord.
Yang H, Zhang Y, Duan Q, Ni K, Jiao Y, Zhu J, Sun J, Zhang W, Ma Z
Molecular pain 2023 Jan-Dec;19:17448069231216234
Molecular pain 2023 Jan-Dec;19:17448069231216234
YAP and β-catenin cooperate to drive H. pylori-induced gastric tumorigenesis.
Li N, Xu X, Zhan Y, Fei X, Ouyang Y, Zheng P, Zhou Y, He C, Xie C, Hu Y, Hong J, Lu N, Ge Z, Zhu Y
Gut microbes 2023 Jan-Dec;15(1):2192501
Gut microbes 2023 Jan-Dec;15(1):2192501
Cryptotanshinone modulates proliferation, apoptosis, and fibrosis through inhibiting AR and EGFR/STAT3 axis to ameliorate benign prostatic hyperplasia progression.
Wei P, Lin D, Zhang M, Luo C, Wu X, Deng B, Cui K, Chen Z
European journal of pharmacology 2023 Jan 5;938:175434
European journal of pharmacology 2023 Jan 5;938:175434
Ring domains are essential for GATOR2-dependent mTORC1 activation.
Jiang C, Dai X, He S, Zhou H, Fang L, Guo J, Liu S, Zhang T, Pan W, Yu H, Fu T, Li D, Inuzuka H, Wang P, Xiao J, Wei W
Molecular cell 2023 Jan 5;83(1):74-89.e9
Molecular cell 2023 Jan 5;83(1):74-89.e9
NAMPT inhibition reduces macrophage inflammation through the NAD+/PARP1 pathway to attenuate liver ischemia-reperfusion injury.
Lu J, Wang M, Chen Y, Song H, Wen D, Tu J, Guo Y, Liu Z
Chemico-biological interactions 2023 Jan 5;369:110294
Chemico-biological interactions 2023 Jan 5;369:110294
Multimodal rehabilitation promotes axonal sprouting and functional recovery in a murine model of spinal cord injury (SCI).
Wang Y, Luo H, Liu Y, Yang C, Yin Y, Tan B
Neuroscience letters 2023 Jan 31;795:137029
Neuroscience letters 2023 Jan 31;795:137029
NLRP3 activation in microglia contributes to learning and memory impairment induced by chronic lead exposure in mice.
Zhu J, Zhou F, Zhou Q, Xu Y, Li Y, Huang D, Chen L, Liu A, Zou F, Meng X
Toxicological sciences : an official journal of the Society of Toxicology 2023 Jan 31;191(1):179-191
Toxicological sciences : an official journal of the Society of Toxicology 2023 Jan 31;191(1):179-191
E2F1 combined with LINC01004 super-enhancer to promote hepatocellular carcinoma cell proliferation and metastasis.
Li J, Wang J, Wang Y, Zhao X, Su T
Clinical epigenetics 2023 Jan 31;15(1):17
Clinical epigenetics 2023 Jan 31;15(1):17
GPR109A controls neutrophil extracellular traps formation and improve early sepsis by regulating ROS/PAD4/Cit-H3 signal axis.
Guo W, Gong Q, Zong X, Wu D, Li Y, Xiao H, Song J, Zhang S, Fu S, Feng Z, Zhuang L
Experimental hematology & oncology 2023 Jan 31;12(1):15
Experimental hematology & oncology 2023 Jan 31;12(1):15
S-Doped carbonized polymer dots inhibit early myocardial fibrosis by regulating mitochondrial function.
Wang Y, Yang M, Zhang J, Ren J, Liu N, Liu B, Lu L, Yang B
Biomaterials science 2023 Jan 31;11(3):894-907
Biomaterials science 2023 Jan 31;11(3):894-907
Inhibition of Checkpoint Kinase 1 (CHK1) Upregulates Interferon Regulatory Factor 1 (IRF1) to Promote Apoptosis and Activate Anti-Tumor Immunity via MICA in Hepatocellular Carcinoma (HCC).
Li X, Huang J, Wu Q, Du Q, Wang Y, Huang Y, Cai X, Geller DA, Yan Y
Cancers 2023 Jan 30;15(3)
Cancers 2023 Jan 30;15(3)
Dietary alpha-ketoglutarate enhances intestinal immunity by Th17/Treg immune response in piglets after lipopolysaccharide challenge.
Liu GM, Lu JJ, Sun WX, Jia G, Zhao H, Chen XL, Tian G, Cai JY, Zhang RN, Wang J
Journal of animal science 2023 Jan 3;101
Journal of animal science 2023 Jan 3;101
Lipopolysaccharide promotes apoptosis and oxidative injury of porcine small intestinal epithelial cells by down-regulating the expression of glutamine transporter ASCT2.
Tang X, Xiong K, Liu J, Li M
Journal of animal science 2023 Jan 3;101
Journal of animal science 2023 Jan 3;101
Activation of autophagy inhibits the activation of NLRP3 inflammasome and alleviates sevoflurane-induced cognitive dysfunction in elderly rats.
Zhou J, Zhang C, Fang X, Zhang N, Zhang X, Zhu Z
BMC neuroscience 2023 Jan 28;24(1):9
BMC neuroscience 2023 Jan 28;24(1):9
ANXA10 is a prognostic biomarker and suppressor of hepatocellular carcinoma: a bioinformatics analysis and experimental validation.
Zhang C, Peng L, Gu H, Wang J, Wang Y, Xu Z
Scientific reports 2023 Jan 28;13(1):1583
Scientific reports 2023 Jan 28;13(1):1583
DHAV 3CD targets IRF7 and RIG-I proteins to block the type I interferon upstream signaling pathway.
Xia X, Cheng A, Wang M, Ou X, Sun D, Zhang S, Mao S, Yang Q, Tian B, Wu Y, Huang J, Gao Q, Jia R, Chen S, Liu M, Zhao XX, Zhu D, Yu Y, Zhang L
Veterinary research 2023 Jan 26;54(1):5
Veterinary research 2023 Jan 26;54(1):5
Ginsenoside Compound K Ameliorates Osteoarthritis by Inhibiting the Chondrocyte Endoplasmic Reticulum Stress-Mediated IRE1α-TXNIP-NLRP3 Axis and Pyroptosis.
Tian Y, Feng X, Zhou Z, Qin S, Chen S, Zhao J, Hou J, Liu D
Journal of agricultural and food chemistry 2023 Jan 25;71(3):1499-1509
Journal of agricultural and food chemistry 2023 Jan 25;71(3):1499-1509
Dendrobine Alleviates Cellular Senescence and Osteoarthritis via the ROS/NF-κB Axis.
Chen H, Tu M, Liu S, Wen Y, Chen L
International journal of molecular sciences 2023 Jan 25;24(3)
International journal of molecular sciences 2023 Jan 25;24(3)
The m(6)A Reader YTHDF1 Promotes Lung Carcinoma Progression via Regulating Ferritin Mediate Ferroptosis in an m(6)A-Dependent Manner.
Diao H, Tan H, Hu Y, Wang R, Cai P, Huang B, Shao X, Yan M, Yin C, Zhang Y
Pharmaceuticals (Basel, Switzerland) 2023 Jan 25;16(2)
Pharmaceuticals (Basel, Switzerland) 2023 Jan 25;16(2)
Proteome-Wide Analysis Reveals TFEB Targets for Establishment of a Prognostic Signature to Predict Clinical Outcomes of Colorectal Cancer.
Huang Z, Zhu S, Han Z, Li C, Liang J, Wang Y, Zhang S, Zhang J
Cancers 2023 Jan 25;15(3)
Cancers 2023 Jan 25;15(3)
Silencing SOX11 Alleviates Allergic Rhinitis by Inhibiting Epithelial-Derived Cytokines.
Jiang L, Wang C, Zhao R, Cao J, Liu Y, Tian L, Liu M
Balkan medical journal 2023 Jan 23;40(1):57-65
Balkan medical journal 2023 Jan 23;40(1):57-65
NFYAv1 is a Tumor-Promoting Transcript Associated with Poor Prognosis of Hepatocellular Carcinoma.
Li Z, You C, Huang J, Zhang M
Medical science monitor : international medical journal of experimental and clinical research 2023 Jan 21;29:e938410
Medical science monitor : international medical journal of experimental and clinical research 2023 Jan 21;29:e938410
SLC17A9-PTHLH-EMT axis promotes proliferation and invasion of clear renal cell carcinoma.
Li W, Xu N, Meng X, Yuan H, Yu T, Miao Q, Yang H, Hai B, Xiao W, Zhang X
iScience 2023 Jan 20;26(1):105764
iScience 2023 Jan 20;26(1):105764
Synthesis of Novel Pentacyclic Triterpenoid Derivatives that Induce Apoptosis in Cancer Cells through a ROS-dependent, Mitochondrial-Mediated Pathway.
Cheng B, Chu X, Liu R, Ma X, Wang M, Zhang J, Jiao P, Gao Q, Ma W, Zhang Y, Zhao C, Zhou D, Xiao S
Molecular pharmaceutics 2023 Jan 2;20(1):701-710
Molecular pharmaceutics 2023 Jan 2;20(1):701-710
Increased endogenous PKG I activity attenuates EGF-induced proliferation and migration of epithelial ovarian cancer via the MAPK/ERK pathway.
Lan T, Li Y, Wang Y, Wang ZC, Mu CY, Tao AB, Gong JL, Zhou Y, Xu H, Li SB, Gu B, Ma P, Luo L
Cell death & disease 2023 Jan 19;14(1):39
Cell death & disease 2023 Jan 19;14(1):39
Construction and Rescue of a DNA-Launched DENV2 Infectious Clone.
Holliday M, Corliss L, Lennemann NJ
Viruses 2023 Jan 18;15(2)
Viruses 2023 Jan 18;15(2)
Inhibition of Klf10 Attenuates Oxidative Stress-Induced Senescence of Chondrocytes via Modulating Mitophagy.
Shang J, Lin N, Peng R, Jiang N, Wu B, Xing B, Lin S, Xu X, Lu H
Molecules (Basel, Switzerland) 2023 Jan 17;28(3)
Molecules (Basel, Switzerland) 2023 Jan 17;28(3)
Robo4 inhibits gamma radiation-induced permeability of a murine microvascular endothelial cell by regulating the junctions.
Adzraku SY, Wang G, Cao C, Bao Y, Wang Y, Smith AO, Du Y, Wang H, Li Y, Xu K, Qiao J, Ju W, Zeng L
Cellular & molecular biology letters 2023 Jan 16;28(1):2
Cellular & molecular biology letters 2023 Jan 16;28(1):2
Analysis of Promoter Methylation of the Bovine FOXO1 Gene and Its Effect on Proliferation and Differentiation of Myoblasts.
Shi P, Ruan Y, Liu W, Sun J, Xu J, Xu H
Animals : an open access journal from MDPI 2023 Jan 16;13(2)
Animals : an open access journal from MDPI 2023 Jan 16;13(2)
N-acetyl-L-cysteine alleviates FUNDC1-mediated mitophagy by regulating mitochondrial dynamics in type 1 diabetic nephropathy canine.
Ma F, Li H, Huo H, Han Q, Liao J, Zhang H, Li Y, Pan J, Hu L, Guo J, Tang Z
Life sciences 2023 Jan 15;313:121278
Life sciences 2023 Jan 15;313:121278
Molecular mechanism of the miR-7/BCL2L1/P53 signaling axis regulating the progression of hepatocellular carcinoma.
Zhang N, Wang F, Zhu L, Chang R, Mok SRS, Peixoto RD, Tang W, Chen Z
Annals of translational medicine 2023 Jan 15;11(1):12
Annals of translational medicine 2023 Jan 15;11(1):12
Exogenous H(2)S Attenuates Hypertension by Regulating Renin Exocytosis under Hyperglycaemic and Hyperlipidaemic Conditions.
Liu N, Li M, Liu S, Kang J, Chen L, Huang J, Wang Y, Chen H, Zhang W
International journal of molecular sciences 2023 Jan 14;24(2)
International journal of molecular sciences 2023 Jan 14;24(2)
The Effect of an Essential Oil Blend on Growth Performance, Intestinal Health, and Microbiota in Early-Weaned Piglets.
Shao Y, Peng Q, Wu Y, Peng C, Wang S, Zou L, Qi M, Peng C, Liu H, Li R, Xiong X, Yin Y
Nutrients 2023 Jan 14;15(2)
Nutrients 2023 Jan 14;15(2)
Glioma-derived LRIG3 interacts with NETO2 in tumor-associated macrophages to modulate microenvironment and suppress tumor growth.
Li Y, Wang W, Hou X, Huang W, Zhang P, He Y, Wang B, Duan Q, Mao F, Guo D
Cell death & disease 2023 Jan 13;14(1):28
Cell death & disease 2023 Jan 13;14(1):28
Oncolytic Hairpin DNA Pair: Selective Cytotoxic Inducer through MicroRNA-Triggered DNA Self-Assembly.
Morihiro K, Osumi H, Morita S, Hattori T, Baba M, Harada N, Ohashi R, Okamoto A
Journal of the American Chemical Society 2023 Jan 11;145(1):135-142
Journal of the American Chemical Society 2023 Jan 11;145(1):135-142
Pulsatilla decoction improves DSS-induced colitis via modulation of fecal-bacteria-related short-chain fatty acids and intestinal barrier integrity.
Niu C, Hu XL, Yuan ZW, Xiao Y, Ji P, Wei YM, Hua YL
Journal of ethnopharmacology 2023 Jan 10;300:115741
Journal of ethnopharmacology 2023 Jan 10;300:115741
The main e-cigarette component vegetable glycerin enhances neutrophil migration and fibrosis in endotoxin-induced lung injury via p38 MAPK activation.
Su VY, Chen WC, Yu WK, Wu HH, Chen H, Yang KY
Respiratory research 2023 Jan 10;24(1):9
Respiratory research 2023 Jan 10;24(1):9
CMTM6 overexpression confers trastuzumab resistance in HER2-positive breast cancer.
Xing F, Gao H, Chen G, Sun L, Sun J, Qiao X, Xue J, Liu C
Molecular cancer 2023 Jan 10;22(1):6
Molecular cancer 2023 Jan 10;22(1):6
Organic extracts in PM2.5 are the major triggers to induce ferroptosis in SH-SY5Y cells.
Guo C, Lyu Y, Xia S, Ren X, Li Z, Tian F, Zheng J
Ecotoxicology and environmental safety 2023 Jan 1;249:114350
Ecotoxicology and environmental safety 2023 Jan 1;249:114350
FSH-inhibited autophagy protects against oxidative stress in goat Sertoli cells through p62-Nrf2 pathway.
Xi H, Hu Z, Han S, Liu X, Wang L, Hu J
Theriogenology 2023 Jan 1;195:103-114
Theriogenology 2023 Jan 1;195:103-114
Proximal tubular Bmal1 protects against chronic kidney injury and renal fibrosis by maintaining of cellular metabolic homeostasis.
Liu C, Li S, Ji S, Zhang J, Zheng F, Guan Y, Yang G, Chen L
Biochimica et biophysica acta. Molecular basis of disease 2023 Jan 1;1869(1):166572
Biochimica et biophysica acta. Molecular basis of disease 2023 Jan 1;1869(1):166572
Daucosterol Alleviates Alcohol-Induced Hepatic Injury and Inflammation through P38/NF-κB/NLRP3 Inflammasome Pathway.
Zhang F, Wang M, Zha Y, Zhou J, Han J, Zhang S
Nutrients 2023 Jan 1;15(1)
Nutrients 2023 Jan 1;15(1)
An interventional study of baicalin on neuronal pentraxin-1, neuronal pentraxin-2, and C-reactive protein in Alzheimer's disease rat model.
Zhao JK, Hou SJ, Zhao JW, Yu HL, Duan SR
Translational neuroscience 2023 Jan 1;14(1):20220298
Translational neuroscience 2023 Jan 1;14(1):20220298
Long noncoding RNA SNHG1 alleviates high glucose-induced vascular smooth muscle cells calcification/senescence by post-transcriptionally regulating Bhlhe40 and autophagy via Atg10.
Li S, Ni Y, Li C, Xiang Q, Zhao Y, Xu H, Huang W, Wang Y, Wang Y, Zhan J, Liu Y
Journal of physiology and biochemistry 2023 Feb;79(1):83-105
Journal of physiology and biochemistry 2023 Feb;79(1):83-105
GOLM1 facilitates human colorectal cancer progression and metastasis via activating the AKT/GSK3β/EMT axis.
Mao Z, Wu Y, Yao P, Xing C
Neoplasma 2023 Feb;70(1):136-144
Neoplasma 2023 Feb;70(1):136-144
Elevated PGT promotes proliferation and inhibits cell apoptosis in preeclampsia by Erk signaling pathway.
Pang H, Lei D, Huang J, Guo Y, Fan C
Molecular and cellular probes 2023 Feb;67:101896
Molecular and cellular probes 2023 Feb;67:101896
The antiviral activity of tripartite motif protein 38 in hepatitis B virus replication and gene expression and its association with treatment responses during PEG-IFN-α antiviral therapy.
Luo H, Hu X, Li Y, Lei D, Tan G, Zeng Y, Qin B
Virology 2023 Feb;579:84-93
Virology 2023 Feb;579:84-93
Huntingtin-associated protein 1 is a potential tumor suppressor for gastric cancer.
Qu YM, Chen A, Zhao X, Wang Z, Guo D, Shao SL, Tao YY, Li QJ, Wang MY, Ma WS
Molecular biology reports 2023 Feb;50(2):1517-1531
Molecular biology reports 2023 Feb;50(2):1517-1531
Dual Antioxidant DH-217 Mitigated Cerebral Ischemia-Reperfusion Injury by Targeting IKKβ/Nrf2/HO-1 Signal Axis.
Shen M, Zheng Y, Li G, Chen Y, Huang L, Wu J, Hong C
Neurochemical research 2023 Feb;48(2):579-590
Neurochemical research 2023 Feb;48(2):579-590
MiR-29c Inhibits TNF-α-Induced ROS Production and Apoptosis in Mouse Hippocampal HT22 Cell Line.
Li B, Lu Y, Wang R, Xu T, Lei X, Jin H, Gao X, Xie Y, Liu X, Zeng J
Neurochemical research 2023 Feb;48(2):519-536
Neurochemical research 2023 Feb;48(2):519-536
cPKCγ Inhibits Caspase-9-Initiated Neuronal Apoptosis in an Ischemia Reperfusion Model In Vitro Through p38 MAPK-p90RSK-Bad Pathway.
Wei HP, Peng ZF, Shao KM, Zhang PH, Chen L, Hu JA, Chai H, Liu JM
Neurochemical research 2023 Feb;48(2):362-374
Neurochemical research 2023 Feb;48(2):362-374
PCSK9 Promotes Endothelial Dysfunction During Sepsis Via the TLR4/MyD88/NF-κB and NLRP3 Pathways.
Huang L, Li Y, Cheng Z, Lv Z, Luo S, Xia Y
Inflammation 2023 Feb;46(1):115-128
Inflammation 2023 Feb;46(1):115-128
Synergistic anticancer effect of flavonoids from Sophora alopecuroides with Sorafenib against hepatocellular carcinoma.
Zhu XF, Sun ZL, Ma J, Hu B, Yu MC, Liu XJ, Yang P, Xu Y, Ju D, Mu Q
Phytotherapy research : PTR 2023 Feb;37(2):592-610
Phytotherapy research : PTR 2023 Feb;37(2):592-610
VEZF1, destabilized by STUB1, affects cellular growth and metastasis of hepatocellular carcinoma by transcriptionally regulating PAQR4.
Shi X, Zhao P, Zhao G
Cancer gene therapy 2023 Feb;30(2):256-266
Cancer gene therapy 2023 Feb;30(2):256-266
S100A1 expression is increased in spinal cord injury and promotes inflammation, oxidative stress and apoptosis of PC12 cells induced by LPS via ERK signaling.
Bai Y, Guo N, Xu Z, Chen Y, Zhang W, Chen Q, Bi Z
Molecular medicine reports 2023 Feb;27(2)
Molecular medicine reports 2023 Feb;27(2)
Turnip crinkle virus-encoded suppressor of RNA silencing interacts with Arabidopsis SGS3 to enhance virus infection.
Liu L, Wang H, Fu Y, Tang W, Zhao P, Ren Y, Liu Z, Wu K, Zhang X
Molecular plant pathology 2023 Feb;24(2):154-166
Molecular plant pathology 2023 Feb;24(2):154-166
Cyasterone inhibits IL-1β-mediated apoptosis and inflammation via the NF-κB and MAPK signaling pathways in rat chondrocytes and ameliorates osteoarthritisin vivo.
Teng L, Shen Y, Qu Y, Yang L, Yang Y, Jian X, Fan S, Zhang L, Fu Q
Chinese journal of natural medicines 2023 Feb;21(2):99-112
Chinese journal of natural medicines 2023 Feb;21(2):99-112
Oleoylethanolamide alleviates hyperlipidaemia-mediated vascular calcification via attenuating mitochondrial DNA stress triggered autophagy-dependent ferroptosis by activating PPARα.
Chen Z, Sun X, Li X, Liu N
Biochemical pharmacology 2023 Feb;208:115379
Biochemical pharmacology 2023 Feb;208:115379
Pharmacological vitamin C inhibits mTOR signaling and tumor growth by degrading Rictor and inducing HMOX1 expression.
Qin S, Wang G, Chen L, Geng H, Zheng Y, Xia C, Wu S, Yao J, Deng L
PLoS genetics 2023 Feb;19(2):e1010629
PLoS genetics 2023 Feb;19(2):e1010629
Neural stem cell-derived exosome as a nano-sized carrier for BDNF delivery to a rat model of ischemic stroke.
Zhu ZH, Jia F, Ahmed W, Zhang GL, Wang H, Lin CQ, Chen WH, Chen LK
Neural regeneration research 2023 Feb;18(2):404-409
Neural regeneration research 2023 Feb;18(2):404-409
Platelet-derived extracellular vesicles ameliorate intervertebral disc degeneration by alleviating mitochondrial dysfunction.
Dai Z, Xia C, Zhao T, Wang H, Tian H, Xu O, Zhu X, Zhang J, Chen P
Materials today. Bio 2023 Feb;18:100512
Materials today. Bio 2023 Feb;18:100512
Plasma microRNA expression profiles associated with zinc exposure and type 2 diabetes mellitus: Exploring potential role of miR-144-3p in zinc-induced insulin resistance.
Ye Z, Cheng M, Fan L, Ma J, Zhang Y, Gu P, Xie Y, You X, Zhou M, Wang B, Chen W
Environment international 2023 Feb;172:107807
Environment international 2023 Feb;172:107807
CXCL11 negatively regulated by MED19 favours antitumour immune infiltration in breast cancer.
Zhang X, Wu J, Hu C, Zheng X, Guo Z, Li L
Cytokine 2023 Feb;162:156106
Cytokine 2023 Feb;162:156106
Exosomes Derived from AT2R-Overexpressing BMSC Prevent Restenosis After Carotid Artery Injury by Attenuating the Injury-Induced Neointimal Hyperplasia.
Zou X, Liao Y, Liu Z, Xu X, Sun W, Qin H, Wang H, Liu J, Jing T
Journal of cardiovascular translational research 2023 Feb;16(1):112-126
Journal of cardiovascular translational research 2023 Feb;16(1):112-126
Exercise induced meteorin-like protects chondrocytes against inflammation and pyroptosis in osteoarthritis by inhibiting PI3K/Akt/NF-κB and NLRP3/caspase-1/GSDMD signaling.
Liu J, Jia S, Yang Y, Piao L, Wang Z, Jin Z, Bai L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Feb;158:114118
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Feb;158:114118
Porous composite hydrogels with improved MSC survival for robust epithelial sealing around implants and M2 macrophage polarization.
Li Y, Zhang J, Wang C, Jiang Z, Lai K, Wang Y, Yang G
Acta biomaterialia 2023 Feb;157:108-123
Acta biomaterialia 2023 Feb;157:108-123
Effects of lactate on metabolism and differentiation of CD4(+)T cells.
Zhang YT, Xing ML, Fang HH, Li WD, Wu L, Chen ZP
Molecular immunology 2023 Feb;154:96-107
Molecular immunology 2023 Feb;154:96-107
Heliangin acts as a covalent ligand of RPS2 that disrupts pre-rRNA metabolic processes in NPM1-mutated acute myeloid leukemia.
Feng Y, Han Y, Hu A, Qu Y, Hu Y, Wu H, Wang X, He L
Acta pharmaceutica Sinica. B 2023 Feb;13(2):598-617
Acta pharmaceutica Sinica. B 2023 Feb;13(2):598-617
PKM2-mediated neuronal hyperglycolysis enhances the risk of Parkinson's disease in diabetic rats.
Zhao Y, Wang Y, Wu Y, Tao C, Xu R, Chen Y, Qian L, Xu T, Lian X
Journal of pharmaceutical analysis 2023 Feb;13(2):187-200
Journal of pharmaceutical analysis 2023 Feb;13(2):187-200
Low dose TGF-β1 can improve vohwinkel syndrome by promoting the proliferation of keratinocytes.
Ling X, Dong S, Zhang L
Acta histochemica 2023 Feb;125(2):152010
Acta histochemica 2023 Feb;125(2):152010
Tumor-derived endomucin promotes colorectal cancer proliferation and metastasis.
Huang Q, Li XM, Sun JP, Zhou Y
Cancer medicine 2023 Feb;12(3):3222-3236
Cancer medicine 2023 Feb;12(3):3222-3236
α-Cyperone protects dopaminergic neurons and inhibits neuroinflammation in LPS-induced Parkinson's disease rat model via activating Nrf2/HO-1 and suppressing NF-κB signaling pathway.
Huang B, Hu G, Zong X, Yang S, He D, Gao X, Liu D
International immunopharmacology 2023 Feb;115:109698
International immunopharmacology 2023 Feb;115:109698
Mesenchymal stem cell-derived extracellular vesicles carrying miR-99b-3p restrain microglial activation and neuropathic pain by stimulating autophagy.
Gao X, Gao LF, Kong XQ, Zhang YN, Jia S, Meng CY
International immunopharmacology 2023 Feb;115:109695
International immunopharmacology 2023 Feb;115:109695
Stevioside targets the NF-κB and MAPK pathways for inhibiting inflammation and apoptosis of chondrocytes and ameliorates osteoarthritis in vivo.
Cai T, Ye H, Jiang H, Lin C, Lou C, Wang W, Yan Z, Xue X, Pan X, Lin J
International immunopharmacology 2023 Feb;115:109683
International immunopharmacology 2023 Feb;115:109683
Ferroptosis is involved in PM2.5-induced acute nasal epithelial injury via AMPK-mediated autophagy.
Gu W, Hou T, Zhou H, Zhu L, Zhu W, Wang Y
International immunopharmacology 2023 Feb;115:109658
International immunopharmacology 2023 Feb;115:109658
IL-33/ST2 mediating systemic inflammation and neuroinflammation through NF-kB participated in the neurocognitive impairment in obstructive sleep apnea.
Dandan-Zong, Shen C, Liu X, Liu T, Ou Y, Ouyang R
International immunopharmacology 2023 Feb;115:109604
International immunopharmacology 2023 Feb;115:109604
Citrus peel ameliorates mucus barrier damage in HFD-fed mice.
Han P, Yu Y, Zhang L, Ruan Z
The Journal of nutritional biochemistry 2023 Feb;112:109206
The Journal of nutritional biochemistry 2023 Feb;112:109206
Preventive effect of salmon sperm DNA on acute carbon tetrachloride-induced liver injury in mice through Nrf2/ARE and mitochondrial apoptosis pathway.
Huang X, Chu X, Tian Y, Xue Y, Zhang L, Li J, Hou H, Dong P, Wang J
Food science & nutrition 2023 Feb;11(2):733-742
Food science & nutrition 2023 Feb;11(2):733-742
Folate inhibits lipid deposition via the autophagy pathway in chicken hepatocytes.
Du ZQ, Pang YQ, Zhang Y, Wang L, Zhang R, Li H, Yang CX
Poultry science 2023 Feb;102(2):102363
Poultry science 2023 Feb;102(2):102363
Research Note: Duck plague virus pUL48 is a late protein that plays an important role in viral replication.
Zhou T, Wang M, Ruan P, Fan D, Cheng A, Zhang W, Tian B, Yang Q, Wu Y, Zhang S, Ou X, Mao S, Huang J, Gao Q, Sun D, Zhao X, Chen S, Liu M, Zhu D, Jia R
Poultry science 2023 Feb;102(2):102358
Poultry science 2023 Feb;102(2):102358
Tryptophan Metabolism Acts as a New Anti-Ferroptotic Pathway to Mediate Tumor Growth.
Liu D, Liang CH, Huang B, Zhuang X, Cui W, Yang L, Yang Y, Zhang Y, Fu X, Zhang X, Du L, Gu W, Wang X, Yin C, Chai R, Chu B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Feb;10(6):e2204006
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Feb;10(6):e2204006
Cholesterol-Lowering Activity of Vitisin A Is Mediated by Inhibiting Cholesterol Biosynthesis and Enhancing LDL Uptake in HepG2 Cells.
Yuan Y, Zhu Y, Li Y, Li X, Jiao R, Bai W
International journal of molecular sciences 2023 Feb 7;24(4)
International journal of molecular sciences 2023 Feb 7;24(4)
Blockage of glycolysis by targeting PFKFB3 suppresses the development of infantile hemangioma.
Yang K, Qiu T, Zhou J, Gong X, Zhang X, Lan Y, Zhang Z, Ji Y
Journal of translational medicine 2023 Feb 6;21(1):85
Journal of translational medicine 2023 Feb 6;21(1):85
Application of neural network-based image analysis to detect sister chromatid cohesion defects.
Ikemoto D, Taniguchi T, Hirota K, Nishikawa K, Okubo K, Abe T
Scientific reports 2023 Feb 6;13(1):2133
Scientific reports 2023 Feb 6;13(1):2133
Ginsenoside Rh2 inhibits CBP/p300-mediated FOXO3a acetylation and epilepsy-induced oxidative damage via the FOXO3a-KEAP1-NRF2 pathway.
Wu J, Wang S, Zhao W, Li M, Li S
European journal of pharmacology 2023 Feb 5;940:175391
European journal of pharmacology 2023 Feb 5;940:175391
Novel ELAC2 Mutations in Individuals Presenting with Variably Severe Neurological Disease in the Presence or Absence of Cardiomyopathy.
Cafournet C, Zanin S, Guimier A, Hully M, Assouline Z, Barcia G, de Lonlay P, Steffann J, Munnich A, Bonnefont JP, Rötig A, Ruzzenente B, Metodiev MD
Life (Basel, Switzerland) 2023 Feb 4;13(2)
Life (Basel, Switzerland) 2023 Feb 4;13(2)
Depletion of SOD2 enhances nasopharyngeal carcinoma cell radiosensitivity via ferroptosis induction modulated by DHODH inhibition.
Amos A, Jiang N, Zong D, Gu J, Zhou J, Yin L, He X, Xu Y, Wu L
BMC cancer 2023 Feb 3;23(1):117
BMC cancer 2023 Feb 3;23(1):117
Glycolysis-related lncRNA TMEM105 upregulates LDHA to facilitate breast cancer liver metastasis via sponging miR-1208.
Han J, Chen X, Wang J, Liu B
Cell death & disease 2023 Feb 3;14(2):80
Cell death & disease 2023 Feb 3;14(2):80
The Protective Role of Scorias spongiosa Polysaccharide-Based Microcapsules on Intestinal Barrier Integrity in DSS-Induced Colitis in Mice.
Xu Y, Feng H, Zhang Z, Zhang Q, Tang J, Zhou J, Wang Y, Peng W
Foods (Basel, Switzerland) 2023 Feb 3;12(3)
Foods (Basel, Switzerland) 2023 Feb 3;12(3)
African Swine Fever Virus L83L Negatively Regulates the cGAS-STING-Mediated IFN-I Pathway by Recruiting Tollip To Promote STING Autophagic Degradation.
Cheng M, Kanyema MM, Sun Y, Zhao W, Lu Y, Wang J, Li X, Shi C, Wang J, Wang N, Yang W, Jiang Y, Huang H, Yang G, Zeng Y, Wang C, Cao X
Journal of virology 2023 Feb 28;97(2):e0192322
Journal of virology 2023 Feb 28;97(2):e0192322
DDX3X Is Hijacked by Snakehead Vesiculovirus Phosphoprotein To Facilitate Virus Replication via Stabilization of the Phosphoprotein.
Bei C, Zhang C, Wu H, Feng H, Zhang YA, Tu J
Journal of virology 2023 Feb 28;97(2):e0003523
Journal of virology 2023 Feb 28;97(2):e0003523
Transcytosable Peptide-Paclitaxel Prodrug Nanoparticle for Targeted Treatment of Triple-Negative Breast Cancer.
Wang L, Zhao C, Lu L, Jiang H, Wang F, Zhang X
International journal of molecular sciences 2023 Feb 28;24(5)
International journal of molecular sciences 2023 Feb 28;24(5)
CENPF promotes the proliferation of renal cell carcinoma in vitro.
Zhang J, Wang Z, Liu Z, Chen Z, Jiang J, Ji Y, Zhang Y, Zhu H, Zheng B
Translational andrology and urology 2023 Feb 28;12(2):320-329
Translational andrology and urology 2023 Feb 28;12(2):320-329
Protective effects of pentoxifylline against chlorine-induced acute lung injury in rats.
Liu MM, Liu JZ, Zhao CQ, Guo P, Wang Z, Wu H, Yu W, Liu R, Hai CX, Zhang XD
BMC pharmacology & toxicology 2023 Feb 27;24(1):12
BMC pharmacology & toxicology 2023 Feb 27;24(1):12
ADSC-derived exosomes attenuate myocardial infarction injury by promoting miR-205-mediated cardiac angiogenesis.
Wang T, Li T, Niu X, Hu L, Cheng J, Guo D, Ren H, Zhao R, Ji Z, Liu P, Li Y, Guo Y
Biology direct 2023 Feb 27;18(1):6
Biology direct 2023 Feb 27;18(1):6
Acupuncture exerts preventive effects in rats of chronic unpredictable mild stress: The involvement of inflammation in amygdala and brain-spleen axis.
Chen W, Chen Y, Cheng W, Li P, Shen J, Tong T, Lai L, Yan S, Huang Z, Li J, Huang S, Meng X
Biochemical and biophysical research communications 2023 Feb 26;646:86-95
Biochemical and biophysical research communications 2023 Feb 26;646:86-95
SERPINF1 Mediates Tumor Progression and Stemness in Glioma.
Song L, Huo X, Li X, Xu X, Zheng Y, Li D, Zhang J, Wang K, Wang L, Wu Z
Genes 2023 Feb 25;14(3)
Genes 2023 Feb 25;14(3)
The total polyphenolic glycoside extract of Lamiophlomis rotata ameliorates hepatic fibrosis through apoptosis by TGF-β/Smad signaling pathway.
Wan G, Chen Z, Lei L, Geng X, Zhang Y, Yang C, Cao W, Pan Z
Chinese medicine 2023 Feb 24;18(1):20
Chinese medicine 2023 Feb 24;18(1):20
1α,25(OH)(2)D(3) Promotes the Autophagy of Porcine Ovarian Granulosa Cells as a Protective Mechanism against ROS through the BNIP3/PINK1 Pathway.
Wang S, Yao Q, Zhao F, Cui W, Price CA, Wang Y, Lv J, Tang H, Jiang Z
International journal of molecular sciences 2023 Feb 22;24(5)
International journal of molecular sciences 2023 Feb 22;24(5)
Anti-tumor effect of infant-derived Enterococcus via the inhibition of proliferation and inflammation as well as the promotion of apoptosis.
Yang Q, He Y, Tian L, Zhang Z, Qiu L, Tao X, Wei H
Food & function 2023 Feb 21;14(4):2223-2238
Food & function 2023 Feb 21;14(4):2223-2238
Anti-glycation and anti-inflammatory activities of anthocyanins from purple vegetables.
Gao Q, Ma R, Shi L, Wang S, Liang Y, Zhang Z
Food & function 2023 Feb 21;14(4):2034-2044
Food & function 2023 Feb 21;14(4):2034-2044
Glioblastoma upregulates SUMOylation of hnRNP A2/B1 to eliminate the tumor suppressor miR-204-3p, accelerating angiogenesis under hypoxia.
Guo Q, Fan Y, Wang Q, Li B, Qiu W, Qi Y, Pan Z, Zhang S, Zhao S, Yang K, Xu H, Li M, Gao Z, Xu J, Wang H, Wang S, Tang Q, Qiu J, Guo X, Deng L, Zhang P, Zhao R, Xue H, Wang C, Li G
Cell death & disease 2023 Feb 21;14(2):147
Cell death & disease 2023 Feb 21;14(2):147
A novel Hoxd13 mutation causes synpolydactyly and promotes osteoclast differentiation by regulating pSmad5/p65/c-Fos/Rank axis.
Zhang L, Fang Z, Cheng G, He M, Lin Y
Cell death & disease 2023 Feb 20;14(2):145
Cell death & disease 2023 Feb 20;14(2):145
Alpha-kinase1 promotes tubular injury and interstitial inflammation in diabetic nephropathy by canonical pyroptosis pathway.
Cui X, Li Y, Yuan S, Huang Y, Chen X, Han Y, Liu Z, Li Z, Xiao Y, Wang Y, Sun L, Liu H, Zhu X
Biological research 2023 Feb 2;56(1):5
Biological research 2023 Feb 2;56(1):5
Exendin-4 alleviates myocardial ischemia reperfusion injury by enhancing autophagy through promoting nuclear translocation of TFEB.
He W, Tong G, Fan H, Zhen C, Zeng L, Xue L, Chen J, Sun Z, He P
Experimental cell research 2023 Feb 15;423(2):113469
Experimental cell research 2023 Feb 15;423(2):113469
Prognosis, immune microenvironment, and personalized treatment prediction in Rho GTPase-activating protein 4-mutant cervical cancer: Computer strategies for precision oncology.
Lu X, Ying Y, Zhang W, Zhang J, Li R, Wang W
Life sciences 2023 Feb 15;315:121360
Life sciences 2023 Feb 15;315:121360
Design, synthesis and anti-AD effects of dual inhibitor targeting glutaminyl cyclase/GSK-3β.
Xie Y, Chen C, Lin S, Yu X, Ye S, Chen X, Ouyang N, Xiong W, Li C, Xu C, Song G, Wu H
European journal of medicinal chemistry 2023 Feb 15;248:115089
European journal of medicinal chemistry 2023 Feb 15;248:115089
Caspase-11 contributes to pain hypersensitivity in the later phase of CFA-induced pain of mice.
Liu M, Cao W, Qin X, Tong J, Wu X, Cheng Y
Brain research 2023 Feb 15;1801:148172
Brain research 2023 Feb 15;1801:148172
Neuroprotective Effects of Sodium Butyrate by Restoring Gut Microbiota and Inhibiting TLR4 Signaling in Mice with MPTP-Induced Parkinson's Disease.
Guo TT, Zhang Z, Sun Y, Zhu RY, Wang FX, Ma LJ, Jiang L, Liu HD
Nutrients 2023 Feb 13;15(4)
Nutrients 2023 Feb 13;15(4)
Rho A/ROCK1 signaling-mediated metabolic reprogramming of valvular interstitial cells toward Warburg effect accelerates aortic valve calcification via AMPK/RUNX2 axis.
Liu H, Yin H, Wang Z, Yuan Q, Xu F, Chen Y, Li C
Cell death & disease 2023 Feb 11;14(2):108
Cell death & disease 2023 Feb 11;14(2):108
Degradation of Perineuronal Nets in the Cerebellar Interpositus Nucleus Ameliorated Social Deficits in Shank3-deficient Mice.
Liu P, Zhao Y, Xiong W, Pan Y, Zhu M, Zhu X
Neuroscience 2023 Feb 10;511:29-38
Neuroscience 2023 Feb 10;511:29-38
UBE2E2 enhances Snail-mediated epithelial-mesenchymal transition and Nrf2-mediated antioxidant activity in ovarian cancer.
Hong X, Ma N, Li D, Zhang M, Dong W, Huang J, Ci X, Zhang S
Cell death & disease 2023 Feb 10;14(2):100
Cell death & disease 2023 Feb 10;14(2):100
Silica nanoparticles suppressed the spermatogenesis via downregulation of miR-450b-3p by targeting Layilin in spermatocyte of mouse.
Zhou G, Wang J, Ren L, Liu J, Li X, Zhang Y, Sang Y, Gao L, Li Y, Sun Z, Zhou X
Environmental pollution (Barking, Essex : 1987) 2023 Feb 1;318:120864
Environmental pollution (Barking, Essex : 1987) 2023 Feb 1;318:120864
The Activation of Reticulophagy by ER Stress through the ATF4-MAP1LC3A-CCPG1 Pathway in Ovarian Granulosa Cells Is Linked to Apoptosis and Necroptosis.
Li H, Jing Y, Qu X, Yang J, Pan P, Liu X, Gao H, Pei X, Zhang C, Yang Y
International journal of molecular sciences 2023 Feb 1;24(3)
International journal of molecular sciences 2023 Feb 1;24(3)
Hypoxia Inhibits Cell Cycle Progression and Cell Proliferation in Brain Microvascular Endothelial Cells via the miR-212-3p/MCM2 Axis.
Shi Q, Li S, Lyu Q, Zhang S, Bai Y, Ma J
International journal of molecular sciences 2023 Feb 1;24(3)
International journal of molecular sciences 2023 Feb 1;24(3)
2-Undecanone alleviates asthma by inhibiting NF-κB pathway.
Song G, Yu S, Zhang Y, Sun M, Zhang B, Peng M
Biochemistry and cell biology = Biochimie et biologie cellulaire 2023 Feb 1;101(1):101-111
Biochemistry and cell biology = Biochimie et biologie cellulaire 2023 Feb 1;101(1):101-111
Estrogen inhibits the differentiation of fibroblasts induced by high stiffness matrix by enhancing DNMT1 expression.
Zhao Z, Huang G, He Y, Zuo X, Han W, Li H
Tissue & cell 2023 Dec;85:102207
Tissue & cell 2023 Dec;85:102207
Discovery of novel pyrido[3,2-d]pyrimidine derivatives as selective and potent PI3Kδ inhibitors.
Bai H, Sun J, Lei H, Zhang SQ, Yuan B, Ma M, Xin M
Drug development research 2023 Dec;84(8):1709-1723
Drug development research 2023 Dec;84(8):1709-1723
The SIRT3 activator ganoderic acid D regulates airway mucin MUC5AC expression via the NRF2/GPX4 pathway.
Wang J, Li J, He Y, Huang X, Feng J, Liu L, Liu Y, Jiang X, Jia J
Pulmonary pharmacology & therapeutics 2023 Dec;83:102262
Pulmonary pharmacology & therapeutics 2023 Dec;83:102262
AKAP12 inhibits esophageal squamous carcinoma cell proliferation, migration, and cell cycle via the PI3K/AKT signaling pathway.
Li X, Dong H, Zheng Y, Ding S, Li Y, Li H, Huang H, Zhong C, Xie T, Xu Y
Molecular and cellular probes 2023 Dec;72:101939
Molecular and cellular probes 2023 Dec;72:101939
Vitamin D Receptor Activation Attenuates Olanzapine-Induced Dyslipidemia in Mice Through Alleviating Hepatic Endoplasmic Reticulum Stress.
Dang R, Wang J, Tang M, Han W, Jiang P
Advanced biology 2023 Dec;7(12):e2300228
Advanced biology 2023 Dec;7(12):e2300228
Dimethyl fumarate ameliorates erectile dysfunction in bilateral cavernous nerve injury rats by inhibiting oxidative stress and NLRP3 inflammasome-mediated pyroptosis of nerve via activation of Nrf2/HO-1 signaling pathway.
Song G, Wang J, Liu J, Ruan Y
Redox biology 2023 Dec;68:102938
Redox biology 2023 Dec;68:102938
Schisandrin B promotes senescence of activated hepatic stellate cell via NCOA4-mediated ferritinophagy.
Ma M, Wei N, Yang J, Ding T, Song A, Chen L, Zheng S, Jin H
Pharmaceutical biology 2023 Dec;61(1):621-629
Pharmaceutical biology 2023 Dec;61(1):621-629
(-)-Epigallocatechin-3-gallate promotes intestinal epithelial proliferation and barrier function after ischemia/reperfusion injury via activation of Nurr1.
Gao J, Wang Y, Jia Z, Xue J, Zhou T, Zu G
Pharmaceutical biology 2023 Dec;61(1):1310-1317
Pharmaceutical biology 2023 Dec;61(1):1310-1317
Glucocorticoid receptors involved in ginsenoside compound K ameliorate adjuvant arthritis by inhibiting the glycolysis of fibroblast-like synoviocytes via the NF-κB/HIF-1α pathway.
Wang Y, Bao X, Xian H, Wei F, Song Y, Zhao S, Zhang Y, Wang Y, Wang Y
Pharmaceutical biology 2023 Dec;61(1):1162-1174
Pharmaceutical biology 2023 Dec;61(1):1162-1174
Mechanisms of dihydromyricetin against hepatocellular carcinoma elucidated by network pharmacology combined with experimental validation.
Zhang S, Shi YN, Gu J, He P, Ai QD, Zhou XD, Wang W, Qin L
Pharmaceutical biology 2023 Dec;61(1):1108-1119
Pharmaceutical biology 2023 Dec;61(1):1108-1119
Intracerebral Hemorrhage-Induced Brain Injury: the Role of Lysosomal-Associated Transmembrane Protein 5.
Hua W, Ma S, Pang Y, Liu Q, Wang Y, Liu Z, Zhao N, Ren N, Jin S, Wang B, Song Y, Qi J
Molecular neurobiology 2023 Dec;60(12):7060-7079
Molecular neurobiology 2023 Dec;60(12):7060-7079
USP10 promotes intrahepatic cholangiocarcinoma cell survival and stemness via SNAI1 deubiquitination.
Zhu W, Ye B, Yang S, Li Y
Journal of molecular histology 2023 Dec;54(6):703-714
Journal of molecular histology 2023 Dec;54(6):703-714
Compound Dihuang Granule Changes Gut Microbiota of MPTP-Induced Parkinson's Disease Mice via Inhibiting TLR4/NF-κB Signaling.
He ZQ, Huan PF, Wang L, He JC
Neurochemical research 2023 Dec;48(12):3610-3624
Neurochemical research 2023 Dec;48(12):3610-3624
Apelin-13 alleviates contrast-induced acute kidney injury by inhibiting endoplasmic reticulum stress.
Liu Q, Duan SB, Wang L, Luo XQ, Wang HS, Deng YH, Wu X, Wu T, Yan And P, Kang YX
Renal failure 2023 Dec;45(1):2179852
Renal failure 2023 Dec;45(1):2179852
Targeting proteasomal deubiquitinases USP14 and UCHL5 with b-AP15 reduces 5-fluorouracil resistance in colorectal cancer cells.
Ding W, Wang JX, Wu JZ, Liu AC, Jiang LL, Zhang HC, Meng Y, Liu BY, Peng GJ, Lou EZ, Mao Q, Zhou H, Tang DL, Chen X, Liu JB, Shi XP
Acta pharmacologica Sinica 2023 Dec;44(12):2537-2548
Acta pharmacologica Sinica 2023 Dec;44(12):2537-2548
Protein Disulfide Isomerase A2 Is Correlated with Immune Infiltrates and Is a Novel Prognostic Biomarker in Glioma Patients.
Ma ZG, Liu YX, Zou N, Huang Z, Wang M, Li T, Zhou J, Chen LG
Current medical science 2023 Dec;43(6):1107-1115
Current medical science 2023 Dec;43(6):1107-1115
Rhein protects retinal Müller cells from high glucose-induced injury via activating the AMPK/Sirt1/PGC-1α pathway.
Liu C, Cao Q, Chen Y, Chen X, Zhu Y, Zhang Z, Wei W
Journal of receptor and signal transduction research 2023 Dec;43(2):62-71
Journal of receptor and signal transduction research 2023 Dec;43(2):62-71
Peripheral BDNF Regulates Somatosensory-Sympathetic Coupling in Brachial Plexus Avulsion-Induced Neuropathic Pain.
Xian H, Guo H, Liu YY, Zhang JL, Hu WC, Yu MJ, Zhao R, Xie RG, Zhang H, Cong R
Neuroscience bulletin 2023 Dec;39(12):1789-1806
Neuroscience bulletin 2023 Dec;39(12):1789-1806
Induction of heme oxygenase-1 antagonizes PM2.5-induced pulmonary VEGFA expression through regulating HIF-1α.
Xu H, Wen Q, Xu X, Liu Z, Liu S, Wang H, Zhang C, Wan D, Liu K, Du L, Yuan C, Song L
Journal of biochemical and molecular toxicology 2023 Dec;37(12):e23494
Journal of biochemical and molecular toxicology 2023 Dec;37(12):e23494
Artificially reprogrammed stem cells deliver transcytosable nanocomplexes for improved spinal cord repair.
Liu X, Zheng Y, Wang Q, Zhao L, Zhang Z, Wang H, Yang Y, Song N, Xiang J, Shen Y, Fan S
Journal of controlled release : official journal of the Controlled Release Society 2023 Dec;364:601-617
Journal of controlled release : official journal of the Controlled Release Society 2023 Dec;364:601-617
Curcumin Alleviates Hepatic Ischemia-Reperfusion Injury by Inhibiting Neutrophil Extracellular Traps Formation.
Zhu C, Shi S, Jiang P, Huang X, Zhao J, Jin Y, Shen Y, Zhou X, Liu H, Cai J
Journal of investigative surgery : the official journal of the Academy of Surgical Research 2023 Dec;36(1):2164813
Journal of investigative surgery : the official journal of the Academy of Surgical Research 2023 Dec;36(1):2164813
miRNA-381 regulates renal cancer stem cell properties and sunitinib resistance via targeting SOX4.
Lu XJ, Gao WW, Li JC, Qin SF
Biochemistry and biophysics reports 2023 Dec;36:101566
Biochemistry and biophysics reports 2023 Dec;36:101566
Effects of heat shock protein 90 on complement activation in myocardial ischemia/reperfusion injury after pioglitazone preconditioning.
Wang D, He S, Zhong G, Meng J, Bi Q, Tu R
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2023 Dec;32(12):1401-1412
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2023 Dec;32(12):1401-1412
The nanoprodrug of polytemozolomide combines with MGMT siRNA to enhance the effect of temozolomide in glioma.
Xu H, Zhang Y, Li L, Ren Y, Qian F, Wang L, Ma H, Quan A, Liu H, Yu R
Drug delivery 2023 Dec;30(1):1-13
Drug delivery 2023 Dec;30(1):1-13
HIF-1α promotes astrocytic production of macrophage migration inhibitory factor following spinal cord injury.
Hao H, Hou Y, Li A, Niu L, Li S, He B, Zhang X, Song H, Cai R, Zhou Y, Yao C, Wang Y, Wang Y
CNS neuroscience & therapeutics 2023 Dec;29(12):3802-3814
CNS neuroscience & therapeutics 2023 Dec;29(12):3802-3814
Vitamin D3 alleviates lung fibrosis of type 2 diabetic rats via SIRT3 mediated suppression of pyroptosis.
Tang L, Zhang D, Zhang Y, Peng Y, Li M, Song H, Chen H, Li W, Li X
Apoptosis : an international journal on programmed cell death 2023 Dec;28(11-12):1618-1627
Apoptosis : an international journal on programmed cell death 2023 Dec;28(11-12):1618-1627
BNIP3 overexpression may promote myeloma cell apoptosis by enhancing sensitivity to bortezomib via the p38 MAPK pathway.
Xiao P, Chen X, Dong Z, Fan W, Chen Y, Su J, Wang Q, Ma L
Hematology (Amsterdam, Netherlands) 2023 Dec;28(1):2231739
Hematology (Amsterdam, Netherlands) 2023 Dec;28(1):2231739
Brusatol enhances MEF2A expression to inhibit RCC progression through the Wnt signalling pathway in renal cell carcinoma.
Wang T, Zhou Y, Bao H, Liu B, Wang M, Wang L, Pan T
Journal of cellular and molecular medicine 2023 Dec;27(23):3897-3910
Journal of cellular and molecular medicine 2023 Dec;27(23):3897-3910
Dihydroartemisinin inhibits liver cancer cell migration and invasion by reducing ATP synthase production through CaMKK2/NCLX.
Chang J, Xin C, Wang Y, Wang Y
Oncology letters 2023 Dec;26(6):540
Oncology letters 2023 Dec;26(6):540
Hsa_circ_0003596 enhances the development of cell renal clear cell carcinoma through the miR-502-5p/IGF1/PI3K/AKT axis.
Fang K, Liang S, Liu D, Yi Q, Li Y, Zhu R
The journal of gene medicine 2023 Dec;25(12):e3562
The journal of gene medicine 2023 Dec;25(12):e3562
20-Deoxyingenol alleviates intervertebral disc degeneration by activating TFEB in nucleus pulposus cells.
Chen Y, Wu C, Zhao X, Tan H, Li C, Deng Y, Chen X, Wu Y, Tian N, Zhang X, Zhou Y, Sun L
Biochemical pharmacology 2023 Dec;218:115865
Biochemical pharmacology 2023 Dec;218:115865
The Combination of Methioninase and Ethionine Exploits Methionine Addiction to Selectively Eradicate Osteosarcoma Cells and Not Normal Cells and Synergistically Down-regulates the Expression of C-MYC.
Aoki Y, Kubota Y, Han Q, Masaki N, Obara K, Bouvet M, Chawla SP, Tome Y, Nishida K, Hoffman RM
Cancer genomics & proteomics 2023 Dec;20(6suppl):679-685
Cancer genomics & proteomics 2023 Dec;20(6suppl):679-685
Identification of antioxidant peptides targeting Keap1-Nrf2-ARE pathway from in vitro digestion of pork sausage with partial substitution of NaCl by KCl.
Zou L, Yu X, Cai K, Xu B, Chen C, Xiao G
Food research international (Ottawa, Ont.) 2023 Dec;174(Pt 1):113585
Food research international (Ottawa, Ont.) 2023 Dec;174(Pt 1):113585
Enzyme-responsive nanospheres target senescent cells for diabetic wound healing by employing chemodynamic therapy.
Wei X, Zheng Z, Liu M, Yang Z, Xie E, Lin J, Gao Y, Tan R, She Z, Ma J, Yang L
Acta biomaterialia 2023 Dec;172:407-422
Acta biomaterialia 2023 Dec;172:407-422
Chemical constituents from Eupatorium fortunei and their anti-inflammatory evaluation by in silico and experimental approaches.
Miao L, Wei QH, Wang ST, Sun P, Zhang H
Fitoterapia 2023 Dec;171:105700
Fitoterapia 2023 Dec;171:105700
Bioinformatics analysis identifies the protective targets of omentin in mice with focal cerebral ischemia injury.
Li W, Liu J, Zhang Q, Ma X, Duan J, Wang J, Tian Y, Shi W
Prostaglandins & other lipid mediators 2023 Dec;169:106780
Prostaglandins & other lipid mediators 2023 Dec;169:106780
Fibroblast growth factor 21 protects the liver from apoptosis in a type 1 diabetes mouse model via regulating L-lactate homeostasis.
Yan J, Xie J, Xu S, Guo Y, Ji K, Li C, Gao H, Zhao L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115737
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115737
The JAK/STAT/NF-κB signaling pathway can be regulated by rosemary essential oil, thereby providing a potential treatment for DNCB-induced in mice.
Li J, Duan J, Wang Y, Zhou P, Wang X, Xia N, Wang J, Li J, Wang W, Wang X, Sun J, Guo D, Zou J, Zhang X, Wang C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115727
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115727
Antinociceptive and neuroprotective effect of echinacoside on peripheral neuropathic pain in mice through inhibiting P2X7R/FKN/CX3CR1 pathway.
Liu N, Zhang GX, Zhu CH, Lan XB, Tian MM, Zheng P, Peng XD, Li YX, Yu JQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115675
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115675
Allantoin Derived From Dioscorea opposita Thunb Ameliorates Cyclophosphamide-Induced Premature Ovarian Failure in Female Rats by Attenuating Apoptosis, Autophagy and Pyroptosis.
Wang X, Yuan P, Zeng M, Sun M, Wang X, Zheng X, Feng W
Cureus 2023 Dec;15(12):e50351
Cureus 2023 Dec;15(12):e50351
Constitutive photomorphogenic protein 1 ubiquitinates interleukin-1 receptor accessory protein in human liver cancer.
Cao K, Liu Z, Liu J, Hu Q, Shan W, Hu B, Shi H, Zhang B
Journal of cancer research and clinical oncology 2023 Dec;149(18):16247-16260
Journal of cancer research and clinical oncology 2023 Dec;149(18):16247-16260
Discovery of selective and potent USP22 inhibitors via structure-based virtual screening and bioassays exerting anti-tumor activity.
Zhang Y, Song J, Zhou Y, Jia H, Zhou T, Sun Y, Gao Q, Zhao Y, Pan Y, Sun Z, Chu P
Bioorganic chemistry 2023 Dec;141:106842
Bioorganic chemistry 2023 Dec;141:106842
Flanking N- and C-terminal domains of PrsA in Streptococcus suis type 2 are crucial for inducing cell death independent of TLR2 recognition.
Jiang X, Yu G, Zhu L, Siddique A, Zhan D, Zhou L, Yue M
Virulence 2023 Dec;14(1):2249779
Virulence 2023 Dec;14(1):2249779
Activation of cGAS-STING signaling pathway promotes liver fibrosis and hepatic sinusoidal microthrombosis.
Luo S, Luo R, Lu H, Zhang R, Deng G, Luo H, Yu X, Wang C, Zhang H, Zhang Y, Huang W, Sun J, Liu Y, Huang F, Lei Z
International immunopharmacology 2023 Dec;125(Pt B):111132
International immunopharmacology 2023 Dec;125(Pt B):111132
Pemetrexed ameliorates Con A-induced hepatic injury by restricting M1 macrophage activation.
Liu Z, Bao Z, Yu B, Chen L, Yang G
International immunopharmacology 2023 Dec;125(Pt A):111158
International immunopharmacology 2023 Dec;125(Pt A):111158
Zinc regulates a specific subpopulation of VEGFA + microglia to improve the hypoxic microenvironment for functional recovery after spinal cord injury.
Deng H, Liu Y, Shi Z, Yang J, Liu C, Mei X
International immunopharmacology 2023 Dec;125(Pt A):111092
International immunopharmacology 2023 Dec;125(Pt A):111092
In vitro validation: GLY alleviates UV-induced corneal epithelial damage through the HMGB1-TLR/MyD88-NF-κB signaling pathway.
Chen X, Zheng X, Shen T, He T, Zhao Y, Dong Y
Acta histochemica 2023 Dec;125(8):152111
Acta histochemica 2023 Dec;125(8):152111
Isovitexin alleviates hepatic fibrosis by regulating miR-21-mediated PI3K/Akt signaling and glutathione metabolic pathway: based on transcriptomics and metabolomics.
Huang Y, Luo W, Chen S, Su H, Zhu W, Wei Y, Qiu Y, Long Y, Shi Y, Wei J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155117
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155117
The effects of astragaloside IV on gut microbiota and serum metabolism in a mice model of intracerebral hemorrhage.
Li Z, Hu E, Zheng F, Wang S, Zhang W, Luo J, Tang T, Huang Q, Wang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155086
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155086
Phosphorylated Hsp27 promotes adriamycin resistance in breast cancer cells through regulating dual phosphorylation of c-Myc.
Bi X, Zhang M, Zhou J, Yan X, Cheng L, Luo L, Huang C, Yin Z
Cellular signalling 2023 Dec;112:110913
Cellular signalling 2023 Dec;112:110913
Activation of AHR by ITE improves cardiac remodelling and function in rats after myocardial infarction.
Lin X, Liu W, Chu Y, Zhang H, Zeng L, Lin Y, Kang K, Peng F, Lin J, Huang C, Chai D
ESC heart failure 2023 Dec;10(6):3622-3636
ESC heart failure 2023 Dec;10(6):3622-3636
LincRNA01703 Facilitates CD81(+) Exosome Secretion to Inhibit Lung Adenocarcinoma Metastasis via the Rab27a/SYTL1/CD81 Complex.
Huang Y, Guo S, Lin Y, Huo L, Yan H, Lin Z, Chen Z, Cai J, Wu J, Yuan J, Guan H, Wu G, Wu W, Tao T
Cancers 2023 Dec 9;15(24)
Cancers 2023 Dec 9;15(24)
Styrax (Liquidambar orientalis Mill.) promotes mitochondrial function and reduces cardiac damage following myocardial ischemic injury: the role of the AMPK-PGC1α signaling pathway.
Mu F, Zhao J, Zhao M, Lin R, Liu K, Zhao S, Tao X, Li W, Dai Q, Xi M, Tang H, Wang J
The Journal of pharmacy and pharmacology 2023 Dec 8;75(12):1496-1508
The Journal of pharmacy and pharmacology 2023 Dec 8;75(12):1496-1508
Molecular Targets and Mechanisms of Casein-Derived Tripeptides Ile-Pro-Pro and Val-Pro-Pro on Hepatic Glucose Metabolism.
Wang C, Zheng L, Zhao M
Journal of agricultural and food chemistry 2023 Dec 6;71(48):18802-18814
Journal of agricultural and food chemistry 2023 Dec 6;71(48):18802-18814
Phenolic Constituents from Black Quinoa Alleviate Insulin Resistance in HepG2 Cells via Regulating IRS1/PI3K/Akt/GLUTs Signaling Pathways.
Cao M, Wang J, Jiang X, Sun Z, Zhao L, Chen G
Journal of agricultural and food chemistry 2023 Dec 6;71(48):18780-18791
Journal of agricultural and food chemistry 2023 Dec 6;71(48):18780-18791
Recombinant human erythropoietin protects against immature brain damage induced by hypoxic/ischemia insult.
Sun Z, Song J, Song Q, Li L, Tian X, Wang L
Neuroreport 2023 Dec 6;34(17):801-810
Neuroreport 2023 Dec 6;34(17):801-810
RUNX1 knockdown induced apoptosis and impaired EMT in high-grade serous ovarian cancer cells.
Chen Y, He Z, Yang S, Chen C, Xiong W, He Y, Liu S
Journal of translational medicine 2023 Dec 6;21(1):886
Journal of translational medicine 2023 Dec 6;21(1):886
Circular RNA circATP9A promotes non-small cell lung cancer progression by interacting with HuR and by promoting extracellular vesicles-mediated macrophage M2 polarization.
Yao Y, Chen C, Wang J, Xuan H, Chen X, Li Z, Yang F, Wang B, Lin S, Li S, Tang D, Gong L, Gao W
Journal of experimental & clinical cancer research : CR 2023 Dec 5;42(1):330
Journal of experimental & clinical cancer research : CR 2023 Dec 5;42(1):330
Exploring the pharmacological mechanisms and key active ingredients of total flavonoids from Lamiophlomis rotata (Benth.) Kudo against rheumatoid arthritis based on multi-technology integrated network pharmacology.
Zhan H, Chen R, Zhong M, Wang G, Jiang G, Tao X, Chen M, Jiang Y
Journal of ethnopharmacology 2023 Dec 5;317:116850
Journal of ethnopharmacology 2023 Dec 5;317:116850
Modification of osimertinib to discover new potent EGFR(C797S)-TK inhibitors.
Xi XX, Zhao HY, Mao YZ, Xin M, Zhang SQ
European journal of medicinal chemistry 2023 Dec 5;261:115865
European journal of medicinal chemistry 2023 Dec 5;261:115865
Discovery of highly potent and selective KRAS(G12C) degraders by VHL-recruiting PROTACs for the treatment of tumors with KRAS(G12C)-Mutation.
Yang N, Fan Z, Sun S, Hu X, Mao Y, Jia C, Cai X, Xu T, Li B, Li Y, Han L, Wei T, Qian X, Qin W, Li P, Zheng Z, Li S
European journal of medicinal chemistry 2023 Dec 5;261:115857
European journal of medicinal chemistry 2023 Dec 5;261:115857
Ethanol extract of Paridis rhizoma attenuates carrageenan-induced paw swelling in rats by inhibiting the production of inflammatory factors.
Xiang L, Huang Q, Chen T, He Q, Yao H, Gao Y
BMC complementary medicine and therapies 2023 Dec 4;23(1):437
BMC complementary medicine and therapies 2023 Dec 4;23(1):437
Canagliflozin ameliorates hypobaric hypoxia-induced pulmonary arterial hypertension by inhibiting pulmonary arterial smooth muscle cell proliferation.
Tang L, Cai Q, Wang X, Li X, Li X, Chen L, Yang Y
Clinical and experimental hypertension (New York, N.Y. : 1993) 2023 Dec 31;45(1):2278205
Clinical and experimental hypertension (New York, N.Y. : 1993) 2023 Dec 31;45(1):2278205
A20 ameliorates Aspergillus fumigatus keratitis by promoting autophagy and inhibiting NF-κB signaling.
Han F, Wang L, Shen L, Liu W, Li Y, Ma H, Wu X
International journal of biological macromolecules 2023 Dec 31;253(Pt 8):127640
International journal of biological macromolecules 2023 Dec 31;253(Pt 8):127640
Mesenchymal stem cell conditioned medium alleviates acute lung injury through KGF-mediated regulation of epithelial sodium channels.
Yu T, Cui Y, Xin S, Fu Y, Ding Y, Hao L, Nie H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115896
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115896
Ramelteon attenuates renal ischemia and reperfusion injury through reducing mitochondrial fission and fusion and inflammation.
Chen P, Liu W, Wei Y
Translational andrology and urology 2023 Dec 31;12(12):1859-1870
Translational andrology and urology 2023 Dec 31;12(12):1859-1870
MicroRNA miR-212-5p Regulates the MEK/ERK Signaling Pathway by Targeting A-Raf proto-oncogene serine/threonine-protein kinase (ARAF) to Regulate Cowshed PM(2.5)-Induced NR8383 Apoptosis.
Sun K, Sun Y, Jia Y, Duan X, Ma Z, Zhang X, Wang L, Zhu Y, Gao Y, Basang W
Toxics 2023 Dec 3;11(12)
Toxics 2023 Dec 3;11(12)
Exosome-Related FTCD Facilitates M1 Macrophage Polarization and Impacts the Prognosis of Hepatocellular Carcinoma.
Liu Y, Tang Y, Jiang H, Zhang X, Chen X, Guo J, Jin C, Wu M
Biomolecules 2023 Dec 28;14(1)
Biomolecules 2023 Dec 28;14(1)
Isoliquiritigenin Inhibits the Growth of Colorectal Cancer Cells through the ESR2/PI3K/AKT Signalling Pathway.
Luo F, Tang Y, Zheng L, Yang Y, Gao H, Tian S, Chen H, Tang C, Tang S, Man Q, Wu Y
Pharmaceuticals (Basel, Switzerland) 2023 Dec 27;17(1)
Pharmaceuticals (Basel, Switzerland) 2023 Dec 27;17(1)
Fucoxanthin diminishes oxidative stress damage in human placenta-derived mesenchymal stem cells through the PI3K/Akt/Nrf-2 pathway.
Suwanmanee G, Tantrawatpan C, Kheolamai P, Paraoan L, Manochantr S
Scientific reports 2023 Dec 27;13(1):22974
Scientific reports 2023 Dec 27;13(1):22974
LINC00921 reduces lung cancer radiosensitivity by destabilizing NUDT21 and driving aberrant MED23 alternative polyadenylation.
Zhang N, Liu X, Huang L, Zeng J, Ma C, Han L, Li W, Yu J, Yang M
Cell reports 2023 Dec 26;42(12):113479
Cell reports 2023 Dec 26;42(12):113479
Exploration of the Pharmacological Mechanism of Vitexicarpin against Triple-Negative Breast Cancer in Network Pharmacology.
Wu T, Xiang M, Li Y, Gao Y, Teng D, Sun M, Guo W, Zhou Y
Frontiers in bioscience (Landmark edition) 2023 Dec 26;28(12):341
Frontiers in bioscience (Landmark edition) 2023 Dec 26;28(12):341
Y-box protein-1 modulates circSPECC1 to promote glioma tumorigenesis via miR-615-5p/HIP1/AKT axis.
Lan P, Li M, Wang Y, Wang J, Li L, Zhang S, Zhang X, Ran C, Zheng J, Gong H
Acta biochimica et biophysica Sinica 2023 Dec 25;55(12):1902-1912
Acta biochimica et biophysica Sinica 2023 Dec 25;55(12):1902-1912
Elevated FBXL6 activates both wild-type KRAS and mutant KRAS(G12D) and drives HCC tumorigenesis via the ERK/mTOR/PRELID2/ROS axis in mice.
Xiong HJ, Yu HQ, Zhang J, Fang L, Wu D, Lin XT, Xie CM
Military Medical Research 2023 Dec 20;10(1):68
Military Medical Research 2023 Dec 20;10(1):68
ER Stress-Perturbed Intracellular Protein O-GlcNAcylation Aggravates Podocyte Injury in Diabetes Nephropathy.
Song S, Hu T, Shi X, Jin Y, Liu S, Li X, Zou W, Wang C
International journal of molecular sciences 2023 Dec 18;24(24)
International journal of molecular sciences 2023 Dec 18;24(24)
Hypoxia promotes the growth and metastasis of ovarian cancer cells by suppressing ferroptosis via upregulating SLC2A12.
Li M, Li L, Cheng X, Li L, Tu K
Experimental cell research 2023 Dec 15;433(2):113851
Experimental cell research 2023 Dec 15;433(2):113851
Identification of the role of MCM6 in bladder cancer prognosis, immunotherapy response, and in vitro experimental investigation using multi-omics analysis.
Wang J, Li X, Chen S, Cao J, Fan X, Wang H, Zhang X, Yang L
Life sciences 2023 Dec 15;335:122253
Life sciences 2023 Dec 15;335:122253
Depletion of gut microbiota facilitates fibroblast growth factor 21-mediated protection against acute pancreatitis in diabetic mice.
Sun QY, Wang XY, Huang ZP, Song J, Zheng ED, Gong FH, Huang XW
World journal of diabetes 2023 Dec 15;14(12):1824-1838
World journal of diabetes 2023 Dec 15;14(12):1824-1838
Transcriptome-wide N(6)-methyladenosine methylation profile of atherosclerosis in mice.
Zheng X, Zhou B, Li Y, Zhong H, Huang Z, Gu M
BMC genomics 2023 Dec 14;24(1):774
BMC genomics 2023 Dec 14;24(1):774
Anti-VEGFR2 F(ab')(2) drug conjugate promotes renal accumulation and glomerular repair in diabetic nephropathy.
Liu D, Song Y, Chen H, You Y, Zhu L, Zhang J, Xu X, Hu J, Huang X, Wu X, Xu X, Jiang S, Du Y
Nature communications 2023 Dec 13;14(1):8268
Nature communications 2023 Dec 13;14(1):8268
Cirsiliol induces autophagy and mitochondrial apoptosis through the AKT/FOXO1 axis and influences methotrexate resistance in osteosarcoma.
Luo M, Su Z, Gao H, Tan J, Liao R, Yang J, Lin L
Journal of translational medicine 2023 Dec 12;21(1):907
Journal of translational medicine 2023 Dec 12;21(1):907
Silk Fibroin-Modified Liposome/Gene Editing System Knocks out the PLK1 Gene to Suppress the Growth of Lung Cancer Cells.
Pan P, Liu X, Fang M, Yang S, Zhang Y, Li M, Liu Y
Pharmaceutics 2023 Dec 12;15(12)
Pharmaceutics 2023 Dec 12;15(12)
Therapeutic protein PAK restrains the progression of triple negative breast cancer through degrading SREBP-1 mRNA.
Hu P, Zhou P, Sun T, Liu D, Yin J, Liu L
Breast cancer research : BCR 2023 Dec 11;25(1):151
Breast cancer research : BCR 2023 Dec 11;25(1):151
Decreased intracellular chloride enhances cell migration and invasion via activation of the ERK1/2 signaling pathway in DU145 human prostate carcinoma cells.
Sato J, Nakano K, Miyazaki H
Biochemical and biophysical research communications 2023 Dec 10;685:149170
Biochemical and biophysical research communications 2023 Dec 10;685:149170
Corilagin attenuates intestinal ischemia/reperfusion injury in mice by inhibiting ferritinophagy-mediated ferroptosis through disrupting NCOA4-ferritin interaction.
Wang Y, Li B, Liu G, Han Q, Diao Y, Liu J
Life sciences 2023 Dec 1;334:122176
Life sciences 2023 Dec 1;334:122176
A comprehensive multiomics approach reveals that high levels of sphingolipids in cardiac cachexia adipose tissue are associated with inflammatory and fibrotic changes.
Qu Y, Wang Y, Wu T, Liu X, Wang H, Ma D
Lipids in health and disease 2023 Dec 1;22(1):211
Lipids in health and disease 2023 Dec 1;22(1):211
An HBV susceptibility variant of KNG1 modulates the therapeutic effects of interferons α and λ1 in HBV infection by promoting MAVS lysosomal degradation.
Zhang B, Han H, Zhao X, Li AN, Wang Y, Yuan W, Yang Z, Li MD
EBioMedicine 2023 Aug;94:104694
EBioMedicine 2023 Aug;94:104694
Dapagliflozin impedes endothelial cell senescence by activating the SIRT1 signaling pathway in type 2 diabetes.
Tai S, Zhou Y, Fu L, Ding H, Zhou Y, Yin Z, Yang R, Liu Z, Zhou S
Heliyon 2023 Aug;9(8):e19152
Heliyon 2023 Aug;9(8):e19152
XBP1s gene of endoplasmic reticulum stress enhances proliferation and osteogenesis of human periodontal ligament cells.
Cui Z, Qin R, Feng J, Liu Y, Zhou X, Qin X, Li Y, Zhang Z, He X
Tissue & cell 2023 Aug;83:102139
Tissue & cell 2023 Aug;83:102139
Salt-inducible kinase inhibition promotes the adipocyte thermogenic program and adipose tissue browning.
Shi F, de Fatima Silva F, Liu D, Patel HU, Xu J, Zhang W, Türk C, Krüger M, Collins S
Molecular metabolism 2023 Aug;74:101753
Molecular metabolism 2023 Aug;74:101753
α-Lactalbumin Peptide Asp-Gln-Trp Ameliorates Hepatic Steatosis and Oxidative Stress in Free Fatty Acids-Treated HepG2 Cells and High-Fat Diet-Induced NAFLD Mice by Activating the PPARα Pathway.
Chen H, Ma Y, Qi X, Tian J, Ma Y, Niu T
Molecular nutrition & food research 2023 Aug;67(16):e2200499
Molecular nutrition & food research 2023 Aug;67(16):e2200499
Title: Bioinformatic Identification of Genes Involved in Diabetic Nephropathy Fibrosis and their Clinical Relevance.
Bai Y, Ma L, Deng D, Tian D, Liu W, Diao Z
Biochemical genetics 2023 Aug;61(4):1567-1584
Biochemical genetics 2023 Aug;61(4):1567-1584
Sirt1 Overexpression Inhibits Fibrous Scar Formation and Improves Functional Recovery After Cerebral Ischemic Injury Through the Deacetylation of 14-3-3ζ.
Chen Y, Huang J, Liu J, Zhu H, Li X, Wen J, Tian M, Ren J, Zhou L, Yang Q
Molecular neurobiology 2023 Aug;60(8):4795-4810
Molecular neurobiology 2023 Aug;60(8):4795-4810
DNA damage-inducible transcript 3 deficiency promotes bone resorption in murine periodontitis models.
Luo Y, Yang B, Dong W, Yu W, Jia M, Wang J
Journal of periodontal research 2023 Aug;58(4):841-851
Journal of periodontal research 2023 Aug;58(4):841-851
Knockdown of CENPN Inhibits Glucose Metabolism and Induces G1 Arrest in Esophageal Cancer Cells by Regulating PI3K/AKT Signaling Pathway.
Xu S, Wei X
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 2023 Aug;55(8):563-572
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 2023 Aug;55(8):563-572
Natural killer cells strengthen antitumor activity of cisplatin by immunomodulation and ameliorate cisplatin-induced side effects.
Wang Z, Yang Z, Qu C, Li J, Wang X
International urology and nephrology 2023 Aug;55(8):1957-1970
International urology and nephrology 2023 Aug;55(8):1957-1970
Repetitive transcranial magnetic stimulation alleviates glial activation through suppressing HMGB1/TLR4 pathway in a rat model of Parkinson's disease.
Han C, Zhang X, Dou K, Yao W, Yao M, Wan Q, Xie A
Molecular biology reports 2023 Aug;50(8):6481-6492
Molecular biology reports 2023 Aug;50(8):6481-6492
Significance of UGT1A6, UGT1A9, and UGT2B7 genetic variants and their mRNA expression in the clinical outcome of renal cell carcinoma.
Matsumoto J, Nishimoto A, Watari S, Ueki H, Shiromizu S, Iwata N, Takeda T, Ushio S, Kajizono M, Fujiyoshi M, Koyama T, Araki M, Wada K, Zamami Y, Nasu Y, Ariyoshi N
Molecular and cellular biochemistry 2023 Aug;478(8):1779-1790
Molecular and cellular biochemistry 2023 Aug;478(8):1779-1790
USP33 enhances cell survival and stemness by deubiquitinating CTNNB1 in BXPC-3 and SW1990 cells.
Zhong B, Zhu Q, Wang L, Wang F, Zheng Y, Lin S, Cheng X
Cell biology international 2023 Aug;47(8):1368-1380
Cell biology international 2023 Aug;47(8):1368-1380
Hydrogen sulfide alleviates beryllium sulfate-induced ferroptosis and ferritinophagy in 16HBE cells.
Liu X, Li G, Chen S, Jin H, Liu X, Zhang L, Zhang Z
Journal of applied toxicology : JAT 2023 Aug;43(8):1169-1182
Journal of applied toxicology : JAT 2023 Aug;43(8):1169-1182
An early-onset SLE patient with a novel paternal inherited BACH2 mutation.
Zhou L, Sun G, Chen R, Chen J, Fang S, Xu Q, Tang W, Dai R, Zhang Z, An Y, Tang X, Zhao X
Journal of clinical immunology 2023 Aug;43(6):1367-1378
Journal of clinical immunology 2023 Aug;43(6):1367-1378
Catalpol Prevents Glomerular Angiogenesis Induced by Advanced Glycation End Products via Inhibiting Galectin-3.
Sun WX, Gao YY, Cao Y, Lu JF, Lv GH, Xu HQ
Current medical science 2023 Aug;43(4):668-678
Current medical science 2023 Aug;43(4):668-678
Naringin protects against inflammation and apoptosis induced by intestinal ischemia-reperfusion injury through deactivation of cGAS-STING signaling pathway.
Gu L, Wang F, Wang Y, Sun D, Sun Y, Tian T, Meng Q, Yin L, Xu L, Lu X, Peng J, Lin Y, Sun P
Phytotherapy research : PTR 2023 Aug;37(8):3495-3507
Phytotherapy research : PTR 2023 Aug;37(8):3495-3507
Klotho gene might antagonize ischemic injury in stroke rats by reducing the expression of AQP4 via P38MAPK pathway.
Zhu G, Xiang T, Liang S, Liu K, Xiao Z, Ye Q
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2023 Aug;32(8):107205
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2023 Aug;32(8):107205
Diosmetin alleviates acute lung injury caused by lipopolysaccharide by targeting barrier function.
Xia J, Li J, Deng M, Yin F, Liu J, Wang J
Inflammopharmacology 2023 Aug;31(4):2037-2047
Inflammopharmacology 2023 Aug;31(4):2037-2047
Extracellular vesicles released by glioma cells are decorated by Annexin A2 allowing for cellular uptake via heparan sulfate.
Song YX, Li X, Nie SD, Hu ZX, Zhou D, Sun DY, Zhou GY, Wang Y, Liu JJ, Song T, Wang S
Cancer gene therapy 2023 Aug;30(8):1156-1166
Cancer gene therapy 2023 Aug;30(8):1156-1166
The role of ROS/p38 MAPK/NLRP3 inflammasome cascade in arsenic-induced depression-/anxiety-like behaviors of mice.
Liu X, Zhang R, Fan J, Chen Y, Wang H, Ge Y, Liang H, Li W, Liu H, Lv Z, Dou W, Jiang H, Li X
Ecotoxicology and environmental safety 2023 Aug;261:115111
Ecotoxicology and environmental safety 2023 Aug;261:115111
Ginsenoside compound K alleviates osteoarthritis by inhibiting NLRP3‑mediated pyroptosis.
Li Y, Wu J, Zhuo N
Experimental and therapeutic medicine 2023 Aug;26(2):406
Experimental and therapeutic medicine 2023 Aug;26(2):406
SOX9/NFIA promotes human ovarian cancer metastasis through the Wnt/β-catenin signaling pathway.
Lu R, Tang P, Zhang D, Lin S, Li H, Feng X, Sun M, Zhang H
Pathology, research and practice 2023 Aug;248:154602
Pathology, research and practice 2023 Aug;248:154602
SlMYB99-mediated auxin and abscisic acid antagonistically regulate ascorbic acids biosynthesis in tomato.
Xu X, Huang B, Fang X, Zhang Q, Qi T, Gong M, Zheng X, Wu M, Jian Y, Deng J, Cheng Y, Li Z, Deng W
The New phytologist 2023 Aug;239(3):949-963
The New phytologist 2023 Aug;239(3):949-963
Rapamycin inhibits corneal inflammatory response and neovascularization in a mouse model of corneal alkali burn.
Li J, Han J, Shi Y, Liu M
Experimental eye research 2023 Aug;233:109539
Experimental eye research 2023 Aug;233:109539
Induction of SGK1 via glucocorticoid-influenced clinical outcome of triple-negative breast cancer patients.
Zhang J, Miki Y, Iwabuchi E, Xu J, Kanai A, Sagara Y, Ohi Y, Rai Y, Yamaguchi R, Tanaka M, Ishida T, Suzuki T, Sasano H
Breast cancer research and treatment 2023 Aug;200(3):323-335
Breast cancer research and treatment 2023 Aug;200(3):323-335
Exosomes from Human Umbilical Cord Mesenchymal Stem Cells Facilitates Injured Endometrial Restoring in Early Repair Period through miR-202-3p Mediating Formation of ECM.
Wang S, Liu T, Nan N, Lu C, Liang M, Wang S, Wang H, He B, Chen X, Xu X, Zheng Y
Stem cell reviews and reports 2023 Aug;19(6):1954-1964
Stem cell reviews and reports 2023 Aug;19(6):1954-1964
M2 Macrophage Membrane-Mediated Biomimetic-Nanoparticle Carrying COX-siRNA Targeted Delivery for Prevention of Tendon Adhesions by Inhibiting Inflammation.
Sun J, Ju F, Jin J, Wang HL, Li ZJ, Sun YC, Chen QZ, Yang QQ, Tan J, Zhou YL
Small (Weinheim an der Bergstrasse, Germany) 2023 Aug;19(33):e2300326
Small (Weinheim an der Bergstrasse, Germany) 2023 Aug;19(33):e2300326
NRF2 activation suppresses motor neuron ferroptosis induced by the SOD1(G93A) mutation and exerts neuroprotection in amyotrophic lateral sclerosis.
Yang B, Pan J, Zhang XN, Wang H, He L, Rong X, Li X, Peng Y
Neurobiology of disease 2023 Aug;184:106210
Neurobiology of disease 2023 Aug;184:106210
Macrophage migration inhibitory factor facilitates astrocytic production of the CCL2 chemokine following spinal cord injury.
Zhang H, Hu YM, Wang YJ, Zhou Y, Zhu ZJ, Chen MH, Wang YJ, Xu H, Wang YH
Neural regeneration research 2023 Aug;18(8):1802-1808
Neural regeneration research 2023 Aug;18(8):1802-1808
Environmentally relevant exposure to cypermethrin aggravates diet-induced diabetic symptoms in mice: The interaction between environmental chemicals and diet.
Wei Y, Liu W, Liu J
Environment international 2023 Aug;178:108090
Environment international 2023 Aug;178:108090
Sodium houttuyfonate plays a protective role in the asthmatic airway by alleviating the NLRP3-related pyroptosis and Th1/Th2 immune imbalance.
Li M, Wang C, Xu WT, Zhong X
Molecular immunology 2023 Aug;160:103-111
Molecular immunology 2023 Aug;160:103-111
Long non-coding RNA ENST00000503625 is a potential prognostic biomarker and metastasis suppressor gene in prostate cancer.
Li Y, Fang Z, Ge S, Li J, Qu L, Shi X, Zhang W, Sun Y, Ren S, Wang L
Journal of cancer research and clinical oncology 2023 Aug;149(10):7305-7317
Journal of cancer research and clinical oncology 2023 Aug;149(10):7305-7317
Genetic and pharmacological inhibition of METTL3 alleviates renal fibrosis by reducing EVL m6A modification through an IGF2BP2-dependent mechanism.
Ni WJ, Zhou H, Lu H, Ma NN, Hou BB, Li W, Kong FX, Yu JT, Hou R, Jin J, Wen JG, Zhang T, Meng XM
Clinical and translational medicine 2023 Aug;13(8):e1359
Clinical and translational medicine 2023 Aug;13(8):e1359
Hypoxia induces the production of epithelial-derived cytokines in eosinophilic chronic rhinosinusitis with nasal polyps.
Zhang M, Tang B, Huang L, Xiong Y, Tu J, Jia Y, Jiang F, Shen L, Luo Q, Ye J
International immunopharmacology 2023 Aug;121:110559
International immunopharmacology 2023 Aug;121:110559
Neutrophils regulate tumor angiogenesis in oral squamous cell carcinoma and the role of Chemerin.
Gao F, Feng Y, Hu X, Zhang X, Li T, Wang Y, Ge S, Wang C, Chi J, Tan X, Wang N
International immunopharmacology 2023 Aug;121:110540
International immunopharmacology 2023 Aug;121:110540
ABCG2 plays a central role in the dysregulation of 25-hydrovitamin D in Crohn's disease.
Peng J, Song X, Zhu F, Zhang C, Xia J, Zou D, Liu J, Yin F, Yin L, Guo H, Liu J
The Journal of nutritional biochemistry 2023 Aug;118:109360
The Journal of nutritional biochemistry 2023 Aug;118:109360
Ketogenic diet alleviates renal interstitial fibrosis in UUO mice by regulating macrophage proliferation.
Hu X, Qiu Y, Cao R, Xu C, Lu C, Wang Z, Yang J
The Journal of nutritional biochemistry 2023 Aug;118:109335
The Journal of nutritional biochemistry 2023 Aug;118:109335
Nervonic acid improves liver inflammation in a mouse model of Parkinson's disease by inhibiting proinflammatory signaling pathways and regulating metabolic pathways.
Wang X, Liang T, Mao Y, Li Z, Li X, Zhu X, Cao F, Zhang J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Aug;117:154911
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Aug;117:154911
O-GlcNAcylation enhances Reticulon 2 protein stability and its promotive effects on gastric cancer progression.
Wang G, Xu Z, Sun J, Liu B, Ruan Y, Gu J, Song S
Cellular signalling 2023 Aug;108:110718
Cellular signalling 2023 Aug;108:110718
NQO1 alleviates renal fibrosis by inhibiting the TLR4/NF-κB and TGF-β/Smad signaling pathways in diabetic nephropathy.
Qiu D, Song S, Chen N, Bian Y, Yuan C, Zhang W, Duan H, Shi Y
Cellular signalling 2023 Aug;108:110712
Cellular signalling 2023 Aug;108:110712
A Recombinant Parathyroid Hormone-Related Peptide Locally Applied in Osteoporotic Bone Defect.
Wang Y, Hu Y, Lan S, Chen Z, Zhang Y, Guo X, Cai L, Li J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Aug;10(22):e2300516
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Aug;10(22):e2300516
Curcumin enhances elvitegravir concentration and alleviates oxidative stress and inflammatory response.
Godse S, Zhou L, Sinha N, Kodidela S, Kumar A, Singh UP, Kumar S
Research square 2023 Aug 9;
Research square 2023 Aug 9;
Diosgenin attenuates nonalcoholic hepatic steatosis through the hepatic FXR-SHP-SREBP1C/PPARα/CD36 pathway.
Chen S, Sun S, Feng Y, Li X, Yin G, Liang P, Yu W, Meng D, Zhang X, Liu H, Zhang F
European journal of pharmacology 2023 Aug 5;952:175808
European journal of pharmacology 2023 Aug 5;952:175808
The effects of acupuncture on depression by regulating BDNF-related balance via lateral habenular nucleus BDNF/TrkB/CREB signaling pathway in rats.
Tong T, Chen Y, Hao C, Shen J, Chen W, Cheng W, Yan S, Li J, Li Y, Gulizhaerkezi T, Zeng J, Meng X
Behavioural brain research 2023 Aug 5;451:114509
Behavioural brain research 2023 Aug 5;451:114509
Cordycepin inhibits ERK pathway to suppress FGF9-induced tumorigenesis with MA-10 mouse Leydig tumor cells.
Chen LC, Chen CY, Lee YP, Huang BM
Journal of food and drug analysis 2023 Aug 31;31(3):485-501
Journal of food and drug analysis 2023 Aug 31;31(3):485-501
SUMOylation of SMAD4 by PIAS1 in Conjunction with Vimentin Upregulation Promotes Migration Potential in Non-Small Cell Lung Cancer.
Wu C, Zhu X, Dai Q, Chu Z, Yang S, Dong Z
Frontiers in bioscience (Landmark edition) 2023 Aug 31;28(8):192
Frontiers in bioscience (Landmark edition) 2023 Aug 31;28(8):192
The cellular uptake of Cordyceps sinensis exopolysaccharide‑selenium nanoparticles and their induced apoptosis of HepG2 cells via mitochondria- and death receptor-mediated pathways.
Zhang X, Xiao Y, Huang Q
International journal of biological macromolecules 2023 Aug 30;247:125747
International journal of biological macromolecules 2023 Aug 30;247:125747
Microglial NLRP3 inflammasome activation mediates diabetes-induced depression-like behavior via triggering neuroinflammation.
Su WJ, Li JM, Zhang T, Cao ZY, Hu T, Zhong SY, Xu ZY, Gong H, Jiang CL
Progress in neuro-psychopharmacology & biological psychiatry 2023 Aug 30;126:110796
Progress in neuro-psychopharmacology & biological psychiatry 2023 Aug 30;126:110796
Antioxidant Behavioural Phenotype in the Immp2l Gene Knock-Out Mouse.
Lawther AJ, Zieba J, Fang Z, Furlong TM, Conn I, Govindaraju H, Choong LLY, Turner N, Siddiqui KS, Bridge W, Merlin S, Hyams TC, Killingsworth M, Eapen V, Clarke RA, Walker AK
Genes 2023 Aug 28;14(9)
Genes 2023 Aug 28;14(9)
The circadian rhythm regulates branched-chain amino acids metabolism in fast muscle of Chinese perch (Siniperca chuatsi) during short-term fasting by Clock-KLF15-Bcat2 pathway.
Zhu X, Liu J, Cai M, Bao L, Pan Y, Wu P, Chu W, Zhang J
The British journal of nutrition 2023 Aug 28;130(4):604-615
The British journal of nutrition 2023 Aug 28;130(4):604-615
Identification of Ecdysteroid Sinapate Esters with COX-2 Inhibitory Effects from Fibraurea recisa Using Molecular Networking and MS2LDA.
Kakumu Y, Thi Nguyen MT, Mitsunaga T, Hattori H
Journal of natural products 2023 Aug 25;86(8):1960-1967
Journal of natural products 2023 Aug 25;86(8):1960-1967
Berberine-loaded MSC-derived sEVs encapsulated in injectable GelMA hydrogel for spinal cord injury repair.
Wang H, Tang Q, Lu Y, Chen C, Zhao YL, Xu T, Yang CW, Chen XQ
International journal of pharmaceutics 2023 Aug 25;643:123283
International journal of pharmaceutics 2023 Aug 25;643:123283
CXCL8 Promotes Endothelial-to-Mesenchymal Transition of Endothelial Cells and Protects Cells from Erastin-Induced Ferroptosis via CXCR2-Mediated Activation of the NF-κB Signaling Pathway.
Ji HZ, Chen L, Ren M, Li S, Liu TY, Chen HJ, Yu HH, Sun Y
Pharmaceuticals (Basel, Switzerland) 2023 Aug 25;16(9)
Pharmaceuticals (Basel, Switzerland) 2023 Aug 25;16(9)
α-Synuclein-carrying astrocytic extracellular vesicles in Parkinson pathogenesis and diagnosis.
Wang P, Lan G, Xu B, Yu Z, Tian C, Lei X, Meissner WG, Feng T, Yang Y, Zhang J
Translational neurodegeneration 2023 Aug 25;12(1):40
Translational neurodegeneration 2023 Aug 25;12(1):40
SYNJ1 rescues motor functions in hereditary and sporadic Parkinson's disease mice by upregulating TSP-1 expression.
Tian Y, Yi S, Guo W, Feng C, Zhang X, Dong H, Wang K, Li R, Tian Y, Gan M, Wu T, Xie H, Gao X
Behavioural brain research 2023 Aug 24;452:114569
Behavioural brain research 2023 Aug 24;452:114569
LncRNA SOCS2-AS1 promotes the progression of papillary thyroid cancer by destabilizing p53 protein.
Zhang X, Zhang X, Yang G, Wan L, Yin F, Li H, Yin D
Biochemical and biophysical research communications 2023 Aug 20;669:95-102
Biochemical and biophysical research communications 2023 Aug 20;669:95-102
WITHDRAWN: Expression of Tmem41b and MMP13 associated with poor outcome in osteosarcomas.
Li GH, Liu X, Feng LJ, Zhang L
Neoplasma 2023 Aug 20;
Neoplasma 2023 Aug 20;
Hypermethylation of RNF125 promotes autophagy-induced oxidative stress in asthma by increasing HMGB1 stability.
Hu J, Ding R, Liu S, Wang J, Li J, Shang Y
iScience 2023 Aug 18;26(8):107503
iScience 2023 Aug 18;26(8):107503
GM-CSF receptor/SYK/JNK/FOXO1/CD11c signaling promotes atherosclerosis.
Tsukui D, Kimura Y, Kono H
iScience 2023 Aug 18;26(8):107293
iScience 2023 Aug 18;26(8):107293
Transcriptomics Reveals Molecular Features of the Bilateral Pelvic Nerve Injury Rat Model of Detrusor Underactivity.
Wang J, Ren L, Liu X, Xu W, Liu M, Hu P, Wang T, Liu J, Ling Q
Biomolecules 2023 Aug 18;13(8)
Biomolecules 2023 Aug 18;13(8)
Lactate dehydrogenase D serves as a novel biomarker for prognosis and immune infiltration in lung adenocarcinoma.
Zhang Y, Zhang T, Zhao Y, Wu H, Zhen Q, Zhu S, Hou S
BMC cancer 2023 Aug 16;23(1):759
BMC cancer 2023 Aug 16;23(1):759
Immunogenic cell death-based prognostic model for predicting the response to immunotherapy and common therapy in lung adenocarcinoma.
Zhou X, Xu R, Lu T, Wang C, Chang X, Peng B, Shen Z, Yao L, Wang K, Xu C, Shi J, Zhang R, Zhao J, Zhang L
Scientific reports 2023 Aug 16;13(1):13305
Scientific reports 2023 Aug 16;13(1):13305
Effects of proanthocyanidins and dialdehyde chitosan on the proliferation and differentiation of bovine myoblast for cultured meat production.
Wang Y, Zhong Z, Wang R, Munawar N, Zan L, Zhu J
International journal of biological macromolecules 2023 Aug 15;246:125618
International journal of biological macromolecules 2023 Aug 15;246:125618
TNFSF14/LIGHT promotes cardiac fibrosis and atrial fibrillation vulnerability via PI3Kγ/SGK1 pathway-dependent M2 macrophage polarisation.
Wu Y, Zhan S, Chen L, Sun M, Li M, Mou X, Zhang Z, Xu L, Xu Y
Journal of translational medicine 2023 Aug 14;21(1):544
Journal of translational medicine 2023 Aug 14;21(1):544
Inhibition of Cxcr4 Disrupts Mouse Embryonic Palatal Mesenchymal Cell Migration and Induces Cleft Palate Occurrence.
Zheng X, Zhao X, Wang Y, Chen J, Wang X, Peng X, Ma L, Du J
International journal of molecular sciences 2023 Aug 13;24(16)
International journal of molecular sciences 2023 Aug 13;24(16)
S100A4 Promotes BCG-Induced Pyroptosis of Macrophages by Activating the NF-κB/NLRP3 Inflammasome Signaling Pathway.
Li M, Liu Y, Nie X, Ma B, Ma Y, Hou Y, Yang Y, Xu J, Wang Y
International journal of molecular sciences 2023 Aug 11;24(16)
International journal of molecular sciences 2023 Aug 11;24(16)
Shoutai Wan regulates glycolysis imbalance at the maternal-fetal interface in threatened abortion mice.
Zhang L, Wang S, Ma Y, Song Y, Li D, Liang X, Hao Y, Jiang M, Lv J, Du H
Journal of ethnopharmacology 2023 Aug 10;312:116502
Journal of ethnopharmacology 2023 Aug 10;312:116502
Ubiquitin-specific protease 7 prevents recurrent spontaneous abortion by targeting enhancer of zeste homolog 2 to regulate trophoblast proliferation, apoptosis, migration, and invasion through the Wnt/β-catenin pathway†.
Zhou M, Gao Y, Wu S, Chen J, Ding J, Wang Y, Yang J
Biology of reproduction 2023 Aug 10;109(2):204-214
Biology of reproduction 2023 Aug 10;109(2):204-214
USP5 promotes lipopolysaccharide-induced apoptosis and inflammatory response by stabilizing the TXNIP protein.
Shi S, Pan X, Chen M, Zhang L, Zhang S, Wang X, Shi S, Chen Z, Lin W, Jiang Y
Hepatology communications 2023 Aug 1;7(8)
Hepatology communications 2023 Aug 1;7(8)
Tumor cells-derived exosomal PD-L1 promotes the growth and invasion of lung cancer cells in vitro via mediating macrophages M2 polarization.
Lu X, Shen J, Huang S, Liu D, Wang H
European journal of histochemistry : EJH 2023 Aug 1;67(3)
European journal of histochemistry : EJH 2023 Aug 1;67(3)
The involvement of let-7 in hCG-induced progesterone synthesis via regulating p27(Kip1) and p21(Cip1) expression.
Chen J, Liu K, Liu W, Yeung WS
Molecular and cellular endocrinology 2023 Aug 1;573:111970
Molecular and cellular endocrinology 2023 Aug 1;573:111970
Apolipoprotein E Polymorphism Impacts White Matter Injury Through Microglial Phagocytosis After Experimental Subarachnoid Hemorrhage.
Li C, Lu P, Zhang L, He Y, Zhang L, Yang L, Zhang F, Kong X, Tao Q, Zhou J, Wu J, Peng T, Xie B, Jiang Y, Peng J
Neuroscience 2023 Aug 1;524:220-232
Neuroscience 2023 Aug 1;524:220-232
Preoperative Pain Facilitates Postoperative Cognitive Dysfunction via Periaqueductal Gray Matter-Dorsal Raphe Circuit.
Deng H, Wu Y, Gao P, Kong D, Pan C, Xu S, Tang D, Jiao Y, Wen D, Yu W
Neuroscience 2023 Aug 1;524:209-219
Neuroscience 2023 Aug 1;524:209-219
Upregulation of postsynaptic cAMP/PKA/CREB signaling alleviates copper(Ⅱ)-induced oxidative stress and pyroptosis in MN9D cells.
Zhou Q, Zhang Y, Lu L, Shi W, Zhang H, Qin W, Wang Y, Pu Y, Yin L
Toxicology 2023 Aug 1;494:153582
Toxicology 2023 Aug 1;494:153582
BDE209-promoted Dio2 degradation in H4 glioma cells through the autophagy pathway, resulting in hypothyroidism and leading to neurotoxicity.
Liu M, Yu Z, Yang F, Zhao Z, Zhou M, Wang C, Zhang B, Liang G, Liu X, Shao J
Toxicology 2023 Aug 1;494:153581
Toxicology 2023 Aug 1;494:153581
Mechanism of aconitine mediated neuronal apoptosis induced by mitochondrial calcium overload caused by MCU.
Jiang C, Shen J, Wang C, Huang Y, Wang L, Yang Y, Hu W, Li P, Wu H
Toxicology letters 2023 Aug 1;384:86-95
Toxicology letters 2023 Aug 1;384:86-95
Ginsenoside Rg1 protects cardiac mitochondrial function via targeting GSTP1 to block S-glutathionylation of optic atrophy 1.
Zhu H, Yan C, Yao P, Li P, Li Y, Yang H
Free radical biology & medicine 2023 Aug 1;204:54-67
Free radical biology & medicine 2023 Aug 1;204:54-67
Combination with vorinostat enhances the antitumor activity of cisplatin in castration-resistant prostate cancer by inhibiting DNA damage repair pathway and detoxification of GSH.
Chang T, Lian Z, Ma S, Liang Z, Ma X, Wen X, Wang Y, Liu R
The Prostate 2023 Apr;83(5):470-486
The Prostate 2023 Apr;83(5):470-486
BST2 regulated by the transcription factor STAT1 can promote metastasis, invasion and proliferation of oral squamous cell carcinoma via the AKT/ERK1/2 signaling pathway.
Shan F, Shen S, Wang X, Chen G
International journal of oncology 2023 Apr;62(4)
International journal of oncology 2023 Apr;62(4)
Astaxanthin promotes mitochondrial biogenesis and antioxidant capacity in chronic high-intensity interval training.
Wang Y, Chen X, Baker JS, Davison GW, Xu S, Zhou Y, Bao X
European journal of nutrition 2023 Apr;62(3):1453-1466
European journal of nutrition 2023 Apr;62(3):1453-1466
Bacillus Calmette-Guérin-induced interleukin-10 inhibits S100A8/A9 production and hinders development of T helper type 1 memory in mice.
Wang Y, Sun Y, Zheng Y, Yang Y, He L, Qu P, Zhou F, Xu X, Bai X, Chen X, Yuan Y, Liu M, Pan Q
European journal of immunology 2023 Apr;53(4):e2250204
European journal of immunology 2023 Apr;53(4):e2250204
Irisin attenuates acute lung injury by suppressing the pyroptosis of alveolar macrophages.
Han Z, Ma J, Han Y, Yuan G, Jiao R, Meng A
International journal of molecular medicine 2023 Apr;51(4)
International journal of molecular medicine 2023 Apr;51(4)
Atractylenolide III suppresses senescence-associated secretome via inhibiting cGAS/NF-κB pathway in hepatic stellate cells.
Wu H, Wu L, Xiao L, Gu Y, Liu H, Zhang L, Zhang M, Qi L
Clinical and experimental pharmacology & physiology 2023 Apr;50(4):316-324
Clinical and experimental pharmacology & physiology 2023 Apr;50(4):316-324
Sufentanil combined with parecoxib sodium inhibits proliferation and metastasis of HER2-positive breast cancer cells and regulates epithelial-mesenchymal transition.
Xu S, Li X, Li W, Ma N, Ma H, Cui J, You X, Chen X
Clinical & experimental metastasis 2023 Apr;40(2):149-160
Clinical & experimental metastasis 2023 Apr;40(2):149-160
Allogeneic gene-edited HIV-specific CAR-T cells secreting PD-1 blocking scFv enhance specific cytotoxic activity against HIV Env(+) cells invivo.
Pan H, Yang X, Wang J, Liang H, Jiang Z, Zhao L, Wang Y, Liang Z, Shen X, Lin Q, Liang Y, Yang J, Lu P, Zhu Y, Li M, Wang P, Xu J, Lu H, Zhu H
Virologica Sinica 2023 Apr;38(2):285-295
Virologica Sinica 2023 Apr;38(2):285-295
Parecoxib attenuates inflammation injury in septic H9c2 cells by regulating the MAPK signaling pathway.
Qian X, Xiong S, Chen Q, Zhang J, Xie J
Experimental and therapeutic medicine 2023 Apr;25(4):150
Experimental and therapeutic medicine 2023 Apr;25(4):150
Polyamines and eIF5A hypusination facilitate SREBP2 synthesis and cholesterol production leading to enhanced enterovirus attachment and infection.
Firpo MR, LoMascolo NJ, Petit MJ, Shah PS, Mounce BC
PLoS pathogens 2023 Apr;19(4):e1011317
PLoS pathogens 2023 Apr;19(4):e1011317
Exosomes incorporated with black phosphorus quantum dots attenuate retinal angiogenesis via disrupting glucose metabolism.
Gui X, Zhang H, Zhang R, Li Q, Zhu W, Nie Z, Zhao J, Cui X, Hao W, Wen X, Shen W, Song H
Materials today. Bio 2023 Apr;19:100602
Materials today. Bio 2023 Apr;19:100602
Ameliorative effects of different doses of selenium against fluoride-triggered apoptosis and oxidative stress-mediated renal injury in rats through the activation of Nrf2/HO-1/NQO1 signaling pathway.
Hu Y, Yan Z, He Y, Li Y, Li M, Li Y, Zhang D, Zhao Y, Ommati MM, Wang J, Huo M, Wang J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Apr;174:113647
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Apr;174:113647
Protective effects of berberine against β-amyloid-induced neurotoxicity in HT22 cells via the Nrf2/HO-1 pathway.
Zhang RL, Lei BX, Wu GY, Wang YY, Huang QH
Bioorganic chemistry 2023 Apr;133:106210
Bioorganic chemistry 2023 Apr;133:106210
Protective efficacy of Schizandrin B on ameliorating nephrolithiasis via regulating GSK3β/Nrf2 signaling-mediated ferroptosis in vivo and in vitro.
Dong C, Song C, He Z, Song Q, Song T, Liu J, Xiong Y, Su X, Zhou J, Yang S, Liao W
International immunopharmacology 2023 Apr;117:110042
International immunopharmacology 2023 Apr;117:110042
Exploring the effect of polyamines on NK cell function in colorectal cancer process based on glycolysis.
He H, Song Z, Lin S, Wang Y, Wang G
International immunopharmacology 2023 Apr;117:109944
International immunopharmacology 2023 Apr;117:109944
Blockade of neutrophil extracellular traps ameliorates toluene diisocyanate-induced steroid-resistant asthma.
Peng X, Li Y, Zhao W, Yang S, Huang J, Chen Y, Wang Y, Gong Z, Chen X, Yu C, Cai S, Zhao H
International immunopharmacology 2023 Apr;117:109719
International immunopharmacology 2023 Apr;117:109719
Silencing of OGDHL promotes liver cancer metastasis by enhancing hypoxia inducible factor 1 α protein stability.
Dai W, Li Y, Sun W, Ji M, Bao R, Chen J, Xu S, Dai Y, Chen Y, Liu W, Ge C, Sun W, Mo W, Guo C, Xu X
Cancer science 2023 Apr;114(4):1309-1323
Cancer science 2023 Apr;114(4):1309-1323
Garlic-derived exosomes regulate PFKFB3 expression to relieve liver dysfunction in high-fat diet-fed mice via macrophage-hepatocyte crosstalk.
Liu J, Li W, Bian Y, Jiang X, Zhu F, Yin F, Yin L, Song X, Guo H, Liu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Apr;112:154679
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Apr;112:154679
Tandem mass tag-based quantitative proteomics analysis reveals the effects of the α-lactalbumin peptides GINY and DQW on lipid deposition and oxidative stress in HepG2 cells.
Chen H, Qi X, Guan K, Wang R, Li Q, Ma Y
Journal of dairy science 2023 Apr;106(4):2271-2288
Journal of dairy science 2023 Apr;106(4):2271-2288
Ccdc25 regulates neurogenesis during the brain development.
Wang C, Qin J, Jiao J, Ji F
Developmental neurobiology 2023 Apr-May;83(3-4):91-103
Developmental neurobiology 2023 Apr-May;83(3-4):91-103
Evaluation of Brown Micro-Algae Synergies With Low Dose γ-Radiation Against Chronic Hepatitis Induced by D-Galactosamine in Rats.
Elsaman S, Elsonbaty SM, Moawed FSM, Hegazy MGA
Dose-response : a publication of International Hormesis Society 2023 Apr-Jun;21(2):15593258231169405
Dose-response : a publication of International Hormesis Society 2023 Apr-Jun;21(2):15593258231169405
Hydrogen peroxide and iron ions can modulate lipid peroxidation, apoptosis, and the cell cycle, but do not have a significant effect on DNA double-strand break.
Yang H, Tai F, Wang T, Zheng X, Ge C, Qin Y, Fu H
Biochemical and biophysical research communications 2023 Apr 9;651:121-126
Biochemical and biophysical research communications 2023 Apr 9;651:121-126
SCAP contributes to embryonic angiogenesis by negatively regulating KISS-1 expression in mice.
Zheng G, Su Y, Wei L, Yao Y, Wang Y, Luo X, Wang X, Ruan XZ, Li D, Chen Y
Cell death & disease 2023 Apr 6;14(4):249
Cell death & disease 2023 Apr 6;14(4):249
Combination treatment with FAAH inhibitors/URB597 and ferroptosis inducers significantly decreases the growth and metastasis of renal cell carcinoma cells via the PI3K-AKT signaling pathway.
Hao J, Chen Q, Feng Y, Jiang Q, Sun H, Deng B, Huang X, Guan J, Chen Q, Liu X, Wang Y, Cao P, Feng F, Li X
Cell death & disease 2023 Apr 6;14(4):247
Cell death & disease 2023 Apr 6;14(4):247
Activation of PPARγ prevents ferroptosis-induced damage through Nrf2/Gpx4 signaling pathway in rat hippocampus following epilepsy.
Wang MJ, Liu X, Chi S, Wang FY, Zhang L, Yao MY, Liu T, Gao J
Neuroreport 2023 Apr 5;34(6):368-374
Neuroreport 2023 Apr 5;34(6):368-374
PGC1α Degradation Suppresses Mitochondrial Biogenesis to Confer Radiation Resistance in Glioma.
Zhao M, Li Y, Lu C, Ding F, Xu M, Ge X, Li M, Wang Z, Yin J, Zhang J, Wang X, Ge Z, Xiao H, Xiao Y, Liu H, Liu W, Cao Y, Wang Q, You Y, Wang X, Yang K, Shi Z, Qian X
Cancer research 2023 Apr 4;83(7):1094-1110
Cancer research 2023 Apr 4;83(7):1094-1110
Scutellarin Alleviates Ischemic Brain Injury in the Acute Phase by Affecting the Activity of Neurotransmitters in Neurons.
Wang C, Liu Y, Liu X, Zhang Y, Yan X, Deng X, Shi J
Molecules (Basel, Switzerland) 2023 Apr 4;28(7)
Molecules (Basel, Switzerland) 2023 Apr 4;28(7)
Lovastatin inhibits erythroleukemia progression through KLF2-mediated suppression of MAPK/ERK signaling.
Gao J, Hu J, Yu F, Wang C, Sheng D, Liu W, Hu A, Yu K, Xiao X, Kuang Y, Zacksenhaus E, Gajendran B, Ben-David Y
BMC cancer 2023 Apr 4;23(1):306
BMC cancer 2023 Apr 4;23(1):306
Epitranscriptic regulation of HRAS by N(6)-methyladenosine drives tumor progression.
Pan Y, Gu Y, Liu T, Zhang Q, Yang F, Duan L, Cheng S, Zhu X, Xi Y, Chang X, Ye Q, Gao S
Proceedings of the National Academy of Sciences of the United States of America 2023 Apr 4;120(14):e2302291120
Proceedings of the National Academy of Sciences of the United States of America 2023 Apr 4;120(14):e2302291120
NMR-Based Metabolic Profiling of the Effects of α-Ketoglutarate Supplementation on Energy-Deficient C2C12 Myotubes.
Li Y, Zhang S, Huang C, Lin D
Molecules (Basel, Switzerland) 2023 Apr 30;28(9)
Molecules (Basel, Switzerland) 2023 Apr 30;28(9)
The Role of LincRNA-EPS/Sirt1/Autophagy Pathway in the Neuroprotection Process by Hydrogen against OGD/R-Induced Hippocampal HT22 Cells Injury.
Li YH, Zhang S, Tang L, Feng J, Jia J, Chen Y, Liu L, Zhou J
Journal of personalized medicine 2023 Apr 3;13(4)
Journal of personalized medicine 2023 Apr 3;13(4)
A novel autophagy-related gene signature associated with prognosis and immune microenvironment in ovarian cancer.
Yang J, Wang C, Zhang Y, Cheng S, Wu M, Gu S, Xu S, Wu Y, Wang Y
Journal of ovarian research 2023 Apr 29;16(1):86
Journal of ovarian research 2023 Apr 29;16(1):86
NCAPG is transcriptionally regulated by CBX3 and activates the Wnt/β-catenin signaling pathway to promote proliferation and the cell cycle and inhibit apoptosis in colorectal cancer.
Yang H, Pu L, Li R, Zhu R
Journal of gastrointestinal oncology 2023 Apr 29;14(2):900-912
Journal of gastrointestinal oncology 2023 Apr 29;14(2):900-912
Study on the pharmacological mechanisms of sodium-glucose co-transporter 2 inhibitors in obesity-related atrial fibrillation based on network pharmacology and experimental verification.
Zhao Q, Wang P, Zhao M, Hong J, Zhang N, Lin K, Li Y
Annals of translational medicine 2023 Apr 28;11(8):300
Annals of translational medicine 2023 Apr 28;11(8):300
RNF123 Mediates Ubiquitination and Degradation of SOCS1 To Regulate Type I Interferon Production during Duck Tembusu Virus Infection.
Huang S, Cui M, Huang J, Wu Z, Cheng A, Wang M, Zhu D, Chen S, Liu M, Zhao X, Wu Y, Yang Q, Zhang S, Ou X, Mao S, Gao Q, Tian B, Sun D, Yin Z, Jing B, Jia R
Journal of virology 2023 Apr 27;97(4):e0009523
Journal of virology 2023 Apr 27;97(4):e0009523
Single-cell sequencing reveals the immune microenvironment landscape related to anti-PD-1 resistance in metastatic colorectal cancer with high microsatellite instability.
Wu T, Zhang X, Liu X, Cai X, Shen T, Pan D, Liang R, Ding R, Hu R, Dong J, Li F, Li J, Xie L, Wang C, Geng S, Yang Z, Xing L, Li Y
BMC medicine 2023 Apr 27;21(1):161
BMC medicine 2023 Apr 27;21(1):161
Two-Pore-Domain Potassium Channel TREK-1 Mediates Pulmonary Fibrosis through Macrophage M2 Polarization and by Direct Promotion of Fibroblast Differentiation.
Zhang Y, Fu J, Han Y, Feng D, Yue S, Zhou Y, Luo Z
Biomedicines 2023 Apr 26;11(5)
Biomedicines 2023 Apr 26;11(5)
SATB1 regulates 3D genome architecture in T cells by constraining chromatin interactions surrounding CTCF-binding sites.
Wang B, Ji L, Bian Q
Cell reports 2023 Apr 25;42(4):112323
Cell reports 2023 Apr 25;42(4):112323
Butyrate dictates ferroptosis sensitivity through FFAR2-mTOR signaling.
Wang G, Qin S, Chen L, Geng H, Zheng Y, Xia C, Yao J, Deng L
Cell death & disease 2023 Apr 25;14(4):292
Cell death & disease 2023 Apr 25;14(4):292
4-Octyl itaconate attenuates LPS-induced acute kidney injury by activating Nrf2 and inhibiting STAT3 signaling.
Xu L, Cai J, Li C, Yang M, Duan T, Zhao Q, Xi Y, Sun L, He L, Tang C, Sun L
Molecular medicine (Cambridge, Mass.) 2023 Apr 24;29(1):58
Molecular medicine (Cambridge, Mass.) 2023 Apr 24;29(1):58
ATF5 regulates tubulointerstitial injury in diabetic kidney disease via mitochondrial unfolded protein response.
Liu Y, Zhang L, Zhang S, Liu J, Li X, Yang K, Yang D, Liu Y, Sun L, Liu F, Xiao L
Molecular medicine (Cambridge, Mass.) 2023 Apr 24;29(1):57
Molecular medicine (Cambridge, Mass.) 2023 Apr 24;29(1):57
Submersion and hypoxia inhibit alveolar epithelial Na(+) transport through ERK/NF-κB signaling pathway.
Zhou W, Hou Y, Yu T, Wang T, Ding Y, Nie H
Respiratory research 2023 Apr 24;24(1):117
Respiratory research 2023 Apr 24;24(1):117
Inhibition of mGluR5 ameliorates lipid accumulation and inflammation in HepG2 cells.
Zeng S, Tao M, Yuan L, Zhang L, Luo X
Biochemical and biophysical research communications 2023 Apr 23;653:1-11
Biochemical and biophysical research communications 2023 Apr 23;653:1-11
High-Dosage NMN Promotes Ferroptosis to Suppress Lung Adenocarcinoma Growth through the NAM-Mediated SIRT1-AMPK-ACC Pathway.
Zhang M, Cui J, Chen H, Wang Y, Kuai X, Sun S, Tang Q, Zong F, Chen Q, Wu J, Wu S
Cancers 2023 Apr 23;15(9)
Cancers 2023 Apr 23;15(9)
Glucose Starvation Inhibits Ferroptosis by Activating the LKB1/AMPK Signaling Pathway and Promotes the High Speed Linear Motility of Dairy Goat Sperm.
Li Y, Zhang G, Wen F, Xian M, Guo S, Zhang X, Feng X, Hu Z, Hu J
Animals : an open access journal from MDPI 2023 Apr 23;13(9)
Animals : an open access journal from MDPI 2023 Apr 23;13(9)
YY1 lactylation in microglia promotes angiogenesis through transcription activation-mediated upregulation of FGF2.
Wang X, Fan W, Li N, Ma Y, Yao M, Wang G, He S, Li W, Tan J, Lu Q, Hou S
Genome biology 2023 Apr 21;24(1):87
Genome biology 2023 Apr 21;24(1):87
Dose-Dependent Effects in Plasma Oncotherapy: Critical In Vivo Immune Responses Missed by In Vitro Studies.
He Y, Gong F, Jin T, Liu Q, Fang H, Chen Y, Wang G, Chu PK, Wu Z, Ostrikov KK
Biomolecules 2023 Apr 21;13(4)
Biomolecules 2023 Apr 21;13(4)
The emerging role of lysine succinylation in ovarian aging.
Le M, Li J, Zhang D, Yuan Y, Zhou C, He J, Huang J, Hu L, Luo T, Zheng L
Reproductive biology and endocrinology : RB&E 2023 Apr 20;21(1):38
Reproductive biology and endocrinology : RB&E 2023 Apr 20;21(1):38
Apurinic/apyrimidinic endonuclease 1 regulates palmitic acid-mediated apoptosis in cardiomyocytes via endoplasmic reticulum stress.
Fan J, Liu M, Li X, Gao S, Wang Y, Li A, Chen L, Zhou D, Chen H, Xu Z, Wu Z, Wu K
Biochemical and biophysical research communications 2023 Apr 2;650:123-131
Biochemical and biophysical research communications 2023 Apr 2;650:123-131
Polystyrene Microplastics Induce Oxidative Stress in Mouse Hepatocytes in Relation to Their Size.
Zou H, Qu H, Bian Y, Sun J, Wang T, Ma Y, Yuan Y, Gu J, Bian J, Liu Z
International journal of molecular sciences 2023 Apr 17;24(8)
International journal of molecular sciences 2023 Apr 17;24(8)
Puerarin protects against sepsis-associated encephalopathy by inhibiting NLRP3/Caspase-1/GSDMD pyroptosis pathway and reducing blood-brain barrier damage.
Zhou S, Li Y, Hong Y, Zhong Z, Zhao M
European journal of pharmacology 2023 Apr 15;945:175616
European journal of pharmacology 2023 Apr 15;945:175616
Selenium supplementation enhanced the expression of selenoproteins in hippocampus and played a neuroprotective role in LPS-induced neuroinflammation.
Liang X, Xue Z, Zheng Y, Li S, Zhou L, Cao L, Zou Y
International journal of biological macromolecules 2023 Apr 15;234:123740
International journal of biological macromolecules 2023 Apr 15;234:123740
AKR1B1 Represses Glioma Cell Proliferation through p38 MAPK-Mediated Bcl-2/BAX/Caspase-3 Apoptotic Signaling Pathways.
Huang YK, Chang KC, Li CY, Lieu AS, Lin CL
Current issues in molecular biology 2023 Apr 13;45(4):3391-3405
Current issues in molecular biology 2023 Apr 13;45(4):3391-3405
Two Resveratrol Oligomers Inhibit Cathepsin L Activity to Suppress SARS-CoV-2 Entry.
Wang C, Ye X, Ding C, Zhou M, Li W, Wang Y, You Q, Zong S, Peng Q, Duanmu D, Chen H, Sun B, Qiao J
Journal of agricultural and food chemistry 2023 Apr 12;71(14):5535-5546
Journal of agricultural and food chemistry 2023 Apr 12;71(14):5535-5546
Cytotoxic Steroidal Saponins Containing a Rare Fructosyl from the Rhizomes of Paris polyphylla var. latifolia.
Li TY, Du Y, Wang MC, Liu K, Liu Y, Cao Y, Wang YY, Chen WW, Qian XY, Qiu PC, Tang HF, Lu YY
International journal of molecular sciences 2023 Apr 12;24(8)
International journal of molecular sciences 2023 Apr 12;24(8)
SLC27A2 mediates FAO in colorectal cancer through nongenic crosstalk regulation of the PPARs pathway.
Shang K, Ma N, Che J, Li H, Hu J, Sun H, Cao B
BMC cancer 2023 Apr 11;23(1):335
BMC cancer 2023 Apr 11;23(1):335
Metformin Collaborates with PINK1/Mfn2 Overexpression to Prevent Cardiac Injury by Improving Mitochondrial Function.
Ma Z, Liu Z, Li X, Zhang H, Han D, Xiong W, Zhou H, Yang X, Zeng Q, Ren H, Xu D
Biology 2023 Apr 11;12(4)
Biology 2023 Apr 11;12(4)
Effects of a ketogenic diet on reproductive and metabolic phenotypes in mice with polycystic ovary syndrome†.
Liu S, Yao Q, Li X, Wu H, Sun C, Bai W, Kang J
Biology of reproduction 2023 Apr 11;108(4):597-610
Biology of reproduction 2023 Apr 11;108(4):597-610
Sea Cucumber Hydrolysate Alleviates Immunosuppression and Gut Microbiota Imbalance Induced by Cyclophosphamide in Balb/c Mice through the NF-κB Pathway.
Mao J, Li S, Fu R, Wang Y, Meng J, Jin Y, Wu T, Zhang M
Foods (Basel, Switzerland) 2023 Apr 10;12(8)
Foods (Basel, Switzerland) 2023 Apr 10;12(8)
Proteomic analysis of DZIP3 interactome and its role in proliferation and metastasis in gastric cancer cells.
Qiu R, Zhao S, Lu C, Xu Z, Shu E, Weng Q, Chen W, Fang S, Chen W, Zheng L, Zhao Z, Yang Y, Ji J
Experimental cell research 2023 Apr 1;425(1):113525
Experimental cell research 2023 Apr 1;425(1):113525
LINC00365 functions as a tumor suppressor by inhibiting HIF-1α-mediated glucose metabolism reprogramming in breast cancer.
Liu B, Qu X, Wang J, Xu L, Zhang L, Xu B, Su J, Bian X
Experimental cell research 2023 Apr 1;425(1):113514
Experimental cell research 2023 Apr 1;425(1):113514
Role of SESTRIN2/AMPK/ULK1 pathway activation and lysosomes dysfunction in NaAsO(2)-induced liver injury under oxidative stress.
Bi D, Zheng D, Shi M, Hu Q, Wang H, Zhi H, Lou D, Zhang A, Hu Y
Ecotoxicology and environmental safety 2023 Apr 1;254:114751
Ecotoxicology and environmental safety 2023 Apr 1;254:114751
Oroxin A ameliorates the oleic acid-induced A549 cell injury through the suppression of pyroptosis and degradation of alveolar surfactant.
Huang J, Chen C, Xie J, Zhai K, Wei S, Cheng X, Zhang R
Anais da Academia Brasileira de Ciencias 2022;94(suppl 4):e20211400
Anais da Academia Brasileira de Ciencias 2022;94(suppl 4):e20211400
Morchella esculenta mushroom polysaccharide attenuates diabetes and modulates intestinal permeability and gut microbiota in a type 2 diabetic mice model.
Rehman AU, Siddiqui NZ, Farooqui NA, Alam G, Gul A, Ahmad B, Asim M, Khan AI, Xin Y, Zexu W, Song Ju H, Xin W, Lei S, Wang L
Frontiers in nutrition 2022;9:984695
Frontiers in nutrition 2022;9:984695
Deficiency of a novel lncRNA-HRAT protects against myocardial ischemia reperfusion injury by targeting miR-370-3p/RNF41 pathway.
Zheng X, Zhong T, Yu F, Duan J, Tang Y, Liu Y, Li M, Sun D, Yin D
Frontiers in cardiovascular medicine 2022;9:951463
Frontiers in cardiovascular medicine 2022;9:951463
Differential expression pattern, bioinformatics analysis, and validation of circRNA and mRNA in patients with arteriosclerosis.
Liu Y, Wang K, Li G, Chen Z
Frontiers in cardiovascular medicine 2022;9:942797
Frontiers in cardiovascular medicine 2022;9:942797
Gypenosides ameliorate high-fat diet-induced non-alcoholic steatohepatitis via farnesoid X receptor activation.
Li H, Xi Y, Liu H, Xin X
Frontiers in nutrition 2022;9:914079
Frontiers in nutrition 2022;9:914079
Effects of Dietary Indole-3-carboxaldehyde Supplementation on Growth Performance, Intestinal Epithelial Function, and Intestinal Microbial Composition in Weaned Piglets.
Zhang R, Huang G, Ren Y, Wang H, Ye Y, Guo J, Wang M, Zhu W, Yu K
Frontiers in nutrition 2022;9:896815
Frontiers in nutrition 2022;9:896815
Integrated Bioinformatic Analysis Reveals TXNRD1 as a Novel Biomarker and Potential Therapeutic Target in Idiopathic Pulmonary Arterial Hypertension.
Lin W, Tang Y, Zhang M, Liang B, Wang M, Zha L, Yu Z
Frontiers in medicine 2022;9:894584
Frontiers in medicine 2022;9:894584
Deoxythymidylate Kinase as a Promising Marker for Predicting Prognosis and Immune Cell Infiltration of Pan-cancer.
Lan T, Wang Y, Miao J, Guo H, Wang Z, Wang J, Zhang C, Yang P, Zhang Z, Dunmall LC, Wang Y
Frontiers in molecular biosciences 2022;9:887059
Frontiers in molecular biosciences 2022;9:887059
Trans-anethole Ameliorates Intestinal Injury Through Activation of Nrf2 Signaling Pathway in Subclinical Necrotic Enteritis-Induced Broilers.
Yu C, Tong Y, Li Q, Wang T, Yang Z
Frontiers in veterinary science 2022;9:877066
Frontiers in veterinary science 2022;9:877066
Human Amnion Epithelial Cells and Their Derived Exosomes Alleviate Sepsis-Associated Acute Kidney Injury via Mitigating Endothelial Dysfunction.
Chi D, Chen Y, Xiang C, Yao W, Wang H, Zheng X, Xu D, Li N, Xie M, Wang S, Liu G, Li S, Yang L
Frontiers in medicine 2022;9:829606
Frontiers in medicine 2022;9:829606
Development and Validation of Novel Prognostic Models for Immune-Related Genes in Osteosarcoma.
Li J, Su L, Xiao X, Wu F, Du G, Guo X, Kong F, Yao J, Zhu H
Frontiers in molecular biosciences 2022;9:828886
Frontiers in molecular biosciences 2022;9:828886
Integrated Strategies of Diverse Feature Selection Methods Identify Aging-Based Reliable Gene Signatures for Ischemic Cardiomyopathy.
Song H, Chen S, Zhang T, Huang X, Zhang Q, Li C, Chen C, Chen S, Liu D, Wang J, Tu Y, Wu Y, Liu Y
Frontiers in molecular biosciences 2022;9:805235
Frontiers in molecular biosciences 2022;9:805235
Identification of Down-Regulated ADH1C is Associated With Poor Prognosis in Colorectal Cancer Using Bioinformatics Analysis.
Li M, Liu Z, Song J, Wang T, Wang H, Wang Y, Guo J
Frontiers in molecular biosciences 2022;9:791249
Frontiers in molecular biosciences 2022;9:791249
1α,25-Dihydroxyvitamin D3 Promotes Angiogenesis After Cerebral Ischemia Injury in Rats by Upregulating the TGF-β/Smad2/3 Signaling Pathway.
Zhang Y, Mu Y, Ding H, Du B, Zhou M, Li Q, Gong S, Zhang F, Geng D, Wang Y
Frontiers in cardiovascular medicine 2022;9:769717
Frontiers in cardiovascular medicine 2022;9:769717
Senescent renal tubular epithelial cells activate fibroblasts by secreting Shh to promote the progression of diabetic kidney disease.
Wang D, Yin L, Chen R, Tan W, Liang L, Xiang J, Zhang H, Zhou X, Deng H, Guo B, Wang Y
Frontiers in medicine 2022;9:1018298
Frontiers in medicine 2022;9:1018298
Dendrobium nobile Lindl. Alkaloids Ameliorate Aβ25-35-Induced Synaptic Deficits by Targeting Wnt/β-Catenin Pathway in Alzheimer's Disease Models.
Zhang W, Zhang M, Wu Q, Shi J
Journal of Alzheimer's disease : JAD 2022;86(1):297-313
Journal of Alzheimer's disease : JAD 2022;86(1):297-313
TRIM47 promotes ovarian cancer cell proliferation, migration, and invasion by activating STAT3 signaling.
Wang X, Fu Y, Xing Y
Clinics (Sao Paulo, Brazil) 2022;77:100122
Clinics (Sao Paulo, Brazil) 2022;77:100122
Correlation between CDK1 protein and CDK1 mRNA during oocyte maturation in mouse.
Sun YT, Zhu AZ
The International journal of developmental biology 2022;66(4-5-6):305-309
The International journal of developmental biology 2022;66(4-5-6):305-309
Wheat oligopeptides enhance the intestinal mucosal barrier and alleviate inflammation via the TLR4/Myd88/MAPK signaling pathway in aged mice.
Xian Y, Da P, Chao Y, Hui X, Ligang Y, Shaokang W, Guiju S
Food & nutrition research 2022;66
Food & nutrition research 2022;66
MiR-328-5p inhibits the adipogenic differentiation of hMSCs by targeting fatty acid synthase.
Li X, He S, Wu P, Zhou Y, Long K, Wang T
Folia histochemica et cytobiologica 2022;60(4):292-300
Folia histochemica et cytobiologica 2022;60(4):292-300
Tooth Loss Induces Memory Impairment and Glial Activation in Young Wild-Type Mice.
Taslima F, Abdelhamid M, Zhou C, Chen Y, Jung CG, Michikawa M
Journal of Alzheimer's disease reports 2022;6(1):663-675
Journal of Alzheimer's disease reports 2022;6(1):663-675
Naringin regulates mitochondrial dynamics to protect against acetaminophen-induced hepatotoxicity by activating the AMPK/Nrf2 signaling pathway in vitro.
Wu Q, Yu P, Bi Y, Li Z, Guo W, Chen Y, Duan Z
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2022;55:e12040
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2022;55:e12040
Benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide induces ferroptosis in neuroblastoma cells through redox imbalance.
Lyu Y, Ren XK, Guo CC, Li ZF, Zheng JP
The Journal of toxicological sciences 2022;47(12):519-529
The Journal of toxicological sciences 2022;47(12):519-529
Evacetrapib Elicits Antitumor Effects on Colorectal Cancer by Inhibiting the Wnt/β-Catenin Signaling Pathway and Activating the JNK Signaling Pathway.
Hu L, Dong H, He L, Shi M, Xiang N, Su Y, Wang C, Tian Y, Hu Y, Wang H, Liu H, Wen C, Yang X
Biological & pharmaceutical bulletin 2022;45(9):1238-1245
Biological & pharmaceutical bulletin 2022;45(9):1238-1245
KIAA1199 Correlates With Tumor Microenvironment and Immune Infiltration in Lung Adenocarcinoma as a Potential Prognostic Biomarker.
Shen X, Mo X, Tan W, Mo X, Li L, Yu F, He J, Deng Z, Xing S, Chen Z, Yang J
Pathology oncology research : POR 2022;28:1610754
Pathology oncology research : POR 2022;28:1610754
Corrigendum to "Berberine Reduces Renal Cell Pyroptosis in Golden Hamsters with Diabetic Nephropathy through the Nrf2-NLRP3-Caspase-1-GSDMD Pathway".
Ding B, Geng S, Hou X, Ma X, Xu H, Yang F, Liu K, Liang W, Ma G
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9828973
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9828973
IL-22 Protects against Biliary Ischemia-Reperfusion Injury after Liver Transplantation via Activating STAT3 and Reducing Apoptosis and Oxidative Stress Levels In Vitro and In Vivo.
Bai Y, Wu H, Zhang J, Zhang S, Zhang Z, Wang H, Zhang Y, Shen Z
Oxidative medicine and cellular longevity 2022;2022:9635075
Oxidative medicine and cellular longevity 2022;2022:9635075
The Effective Analysis for Blue Honeysuckle Extract in the Treatment of Hepatocellular Carcinoma.
Zhang CP, Li WH, Liu JR, Li GD, Zhang HP, Wei JF, Chen HS, Zhao JL, Wang YF, Lv Q, Liu M
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9601020
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9601020
Actin-Binding LIM 1 (ABLIM1) Inhibits Glioblastoma Progression and Serves as a Novel Prognostic Biomarker.
Liu D, Wang X, Liu Y, Li C, Zhang Z, Lv P
Disease markers 2022;2022:9516808
Disease markers 2022;2022:9516808
DNA Methyltransferase Inhibitor 5-AZA-DC Regulates TGFβ1-Mediated Alteration of Neuroglial Cell Functions after Oxidative Stress.
Zhao XY, Zhang XL
Oxidative medicine and cellular longevity 2022;2022:9259465
Oxidative medicine and cellular longevity 2022;2022:9259465
Artesunate Suppresses the Growth of Lung Cancer Cells by Downregulating the AKT/Survivin Signaling Pathway.
Zhang W, Ning N, Huang J
BioMed research international 2022;2022:9170053
BioMed research international 2022;2022:9170053
HBO Alleviates Neural Stem Cell Pyroptosis via lncRNA-H19/miR-423-5p/NLRP3 Axis and Improves Neurogenesis after Oxygen Glucose Deprivation.
Ye Y, Feng Z, Tian S, Yang Y, Jia Y, Wang G, Wang J, Bai W, Li J, He X
Oxidative medicine and cellular longevity 2022;2022:9030771
Oxidative medicine and cellular longevity 2022;2022:9030771
Ginsenoside Rg1 Inhibits STAT3 Expression by miR-15b-5p to Attenuate Lung Injury in Mice with Type 2 Diabetes Mellitus-Associated Pulmonary Tuberculosis.
Ma T, Mao X, Meng X, Wang Q
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9017021
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9017021
Inhibitory Effects of Parachlorella Beijerinckii Extracts on the Formation of Advanced Glycation End Products and Glycative Stress-Induced Inflammation in an In Vitro Skin Dermis-Like Model.
Imai Y, Nakashima Y, Kanno T
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8789903
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8789903
Cystathionine β-Synthase Regulates the Proliferation, Migration, and Invasion of Thyroid Carcinoma Cells.
Jiang QY, Li JM, Jing MR, Zhang YX, Zhang QQ, Cai CB, Wang D, Qi HW, Li T, Li YZ, Ji XY, Wu DD
Oxidative medicine and cellular longevity 2022;2022:8678363
Oxidative medicine and cellular longevity 2022;2022:8678363
Loureirin A Exerts Antikeloid Activity by Antagonizing the TGF-β1/Smad Signalling Pathway.
Ma H, Duan X, Zhang R, Li H, Guo Y, Tian Y, Huang M, Chen G, Wang Z, Li L
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8661288
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8661288
Dl-3-n-Butylphthalide Improves Neuroinflammation in Mice with Repeated Cerebral Ischemia-Reperfusion Injury through the Nrf2-Mediated Antioxidant Response and TLR4/MyD88/NF-κB Signaling Pathway.
Gao Y, Hu M, Niu X, Li M, Xu L, Xiao Y, Zhang J, Wang H, Li L, Chu B, Lv P
Oxidative medicine and cellular longevity 2022;2022:8652741
Oxidative medicine and cellular longevity 2022;2022:8652741
Preliminary Evaluation of Artificial Intelligence-Based Anti-Hepatocellular Carcinoma Molecular Target Study in Hepatocellular Carcinoma Diagnosis Research.
Wang Y, Wei C, Deng X, Gao S, Chen J
BioMed research international 2022;2022:8365565
BioMed research international 2022;2022:8365565
Activation of PPARγ Protects Obese Mice from Acute Lung Injury by Inhibiting Endoplasmic Reticulum Stress and Promoting Mitochondrial Biogenesis.
Tang Y, Wei K, Liu L, Ma J, Wu S, Tang W
PPAR research 2022;2022:7888937
PPAR research 2022;2022:7888937
Recurrent Hypoglycemia Impaired Vascular Function in Advanced T2DM Rats by Inducing Pyroptosis.
Luo M, Hu Y, Lv D, Xie L, Yang S, Zuo D, Xue Y, He A
Oxidative medicine and cellular longevity 2022;2022:7812407
Oxidative medicine and cellular longevity 2022;2022:7812407
Hypoxia-Induced miR-210 Promotes Endothelial Cell Permeability and Angiogenesis via Exosomes in Pancreatic Ductal Adenocarcinoma.
Wu G, Ding X, Quan G, Xiong J, Li Q, Li Z, Wang Y
Biochemistry research international 2022;2022:7752277
Biochemistry research international 2022;2022:7752277
Effect of Thymoquinone on Renal Damage Induced by Hyperlipidemia in LDL Receptor-Deficient (LDL-R(-)/(-)) Mice.
Li W, Zhang H, Zhang L, Zhang T, Ding H
BioMed research international 2022;2022:7709926
BioMed research international 2022;2022:7709926
Astragali Radix-Coptis Rhizoma Herb Pair Attenuates Atherosclerosis in ApoE-/- Mice by Regulating the M1/M2 and Th1/Th2 Immune Balance and Activating the STAT6 Signaling Pathway.
Li Z, Ma D, Wang Y, Wu S, Wang L, Jiang Y, Zhang Y, Li X
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7421265
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7421265
TLR4 Modulates Senescence and Paracrine Action in Placental Mesenchymal Stem Cells via Inhibiting Hedgehog Signaling Pathway in Preeclampsia.
Zhong Y, Zhang Y, Liu W, Zhao Y, Zou L, Liu X
Oxidative medicine and cellular longevity 2022;2022:7202837
Oxidative medicine and cellular longevity 2022;2022:7202837
Rhein Inhibits the Progression of Chemoresistant Lung Cancer Cell Lines via the Stat3/Snail/MMP2/MMP9 Pathway.
Liu J, Ding D, Liu F, Chen Y
BioMed research international 2022;2022:7184871
BioMed research international 2022;2022:7184871
Transmissible Endoplasmic Reticulum Stress Mediated by Extracellular Vesicles from Adipocyte Promoting the Senescence of Adipose-Derived Mesenchymal Stem Cells in Hypertrophic Obesity.
Fang J, Li L, Cao X, Yue H, Fu W, Chen Y, Xu Z, Zhao Q, Zhao J, Wang Y, Liang W
Oxidative medicine and cellular longevity 2022;2022:7175027
Oxidative medicine and cellular longevity 2022;2022:7175027
Silencing CAMK2D Promotes the Proliferation of Spermatogonia in the Testis of Experimental Varicocele Rats.
Tang S, Yang P, Ding Y, Chen Q, Huang H, Chen X, Zhou H
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7121245
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7121245
EGCG Enhances the Chemosensitivity of Colorectal Cancer to Irinotecan through GRP78-MediatedEndoplasmic Reticulum Stress.
Wu W, Gou H, Xiang B, Geng R, Dong J, Yang X, Chen D, Dai R, Chen L, Liu J
Journal of oncology 2022;2022:7099589
Journal of oncology 2022;2022:7099589
Protection of Human Lens Epithelial Cells from Oxidative Stress Damage and Cell Apoptosis by KGF-2 through the Akt/Nrf2/HO-1 Pathway.
Liu S, Jin Z, Xia R, Zheng Z, Zha Y, Wang Q, Wan X, Yang H, Cai J
Oxidative medicine and cellular longevity 2022;2022:6933812
Oxidative medicine and cellular longevity 2022;2022:6933812
Inhibition of Bruton's Tyrosine Kinase Alleviates Monocrotaline-Induced Pulmonary Arterial Hypertension by Modulating Macrophage Polarization.
Yu M, Wu X, Peng L, Yang M, Zhou H, Xu J, Wang J, Wang H, Xie W, Kong H
Oxidative medicine and cellular longevity 2022;2022:6526036
Oxidative medicine and cellular longevity 2022;2022:6526036
Multifunctional Drug-Loaded Phase-Change Nanoparticles Inhibit the Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma by Affecting the Activity of Activated Hepatic Stellate Cells.
Zou X, Li T, Mao Y, Zhu M, Chen X, Niu J, Dong T, Jiang J, Yang X
BioMed research international 2022;2022:6441179
BioMed research international 2022;2022:6441179
Therapeutic Potential of Synthetic Human β-Defensin 1 Short Motif Pep-B on Lipopolysaccharide-Stimulated Human Dental Pulp Stem Cells.
Shi J, Hu Z, Zhou Y, Zuo M, Wu H, Jin W, Xie Z
Mediators of inflammation 2022;2022:6141967
Mediators of inflammation 2022;2022:6141967
ProNGF/NGF Modulates Autophagy and Apoptosis through PI3K/Akt/mTOR and ERK Signaling Pathways following Cerebral Ischemia-Reperfusion in Rats.
Li Y, Wu F, Zhou M, Zhou J, Cui S, Guo J, Wu J, He L
Oxidative medicine and cellular longevity 2022;2022:6098191
Oxidative medicine and cellular longevity 2022;2022:6098191
Inhibition of APE1 Expression Enhances the Antitumor Activity of Olaparib in Triple-Negative Breast Cancer.
Jian D, Li XM, Dai N, Liang DD, Zhang G, Mao CY, Wang D, Song GB, Li MX, Luo H
Evidence-based complementary and alternative medicine : eCAM 2022;2022:6048017
Evidence-based complementary and alternative medicine : eCAM 2022;2022:6048017
Magnesium Hydride Ameliorates Endotoxin-Induced Acute Respiratory Distress Syndrome by Inhibiting Inflammation, Oxidative Stress, and Cell Apoptosis.
Shi X, Zhu L, Wang S, Zhu W, Li Q, Wei J, Feng D, Liu M, Chen Y, Sun X, Lu H, Lv X
Oxidative medicine and cellular longevity 2022;2022:5918954
Oxidative medicine and cellular longevity 2022;2022:5918954
Saikosaponin D Inducing Apoptosis and Autophagy through the Activation of Endoplasmic Reticulum Stress in Glioblastoma.
Liu G, Guan Y, Liu Y, Wang Y, Zhang J, Liu Y, Liu X
BioMed research international 2022;2022:5489553
BioMed research international 2022;2022:5489553
The Effects of Hedgehog Signaling Pathway on the Proliferation and Apoptosis of Melanoma Cells.
Peng ZP, Huang SF, Li JJ, Tang XK, Wang XY, Li HM
Journal of oncology 2022;2022:4984866
Journal of oncology 2022;2022:4984866
Downregulation of FXYD2 Is Associated with Poor Prognosis and Increased Regulatory T Cell Infiltration in Clear Cell Renal Cell Carcinoma.
Zhang Z, Tang Y, Li L, Yang W, Xu Y, Zhou J, Ma K, Zhang K, Zhuang H, Gong Y, Gong K
Journal of immunology research 2022;2022:4946197
Journal of immunology research 2022;2022:4946197
Melatonin Alleviates Acute Kidney Injury by Inhibiting NRF2/Slc7a11 Axis-Mediated Ferroptosis.
Huang YB, Jiang L, Liu XQ, Wang X, Gao L, Zeng HX, Zhu W, Hu XR, Wu YG
Oxidative medicine and cellular longevity 2022;2022:4776243
Oxidative medicine and cellular longevity 2022;2022:4776243
Sodium Butyrate Attenuated Diabetes-Induced Intestinal Inflammation by Modulating Gut Microbiota.
Liu L, Chen Y, Wu Q, Shu A, Sun J
Evidence-based complementary and alternative medicine : eCAM 2022;2022:4646245
Evidence-based complementary and alternative medicine : eCAM 2022;2022:4646245
Evodiamine as the Active Compound of Evodiae fructus to Inhibit Proliferation and Migration of Prostate Cancer through PI3K/AKT/NF-κB Signaling Pathway.
Lei Y, Chan M, Liu H, Lyu W, Chen L, Zhong Y, Gan H, Wang M, Qi M, Guo Y, Liu J, Zhang E
Disease markers 2022;2022:4399334
Disease markers 2022;2022:4399334
IL6 Induces mtDNA Leakage to Affect the Immune Escape of Endometrial Carcinoma via cGAS-STING.
Zeng X, Li X, Zhang Y, Cao C, Zhou Q
Journal of immunology research 2022;2022:3815853
Journal of immunology research 2022;2022:3815853
Molecular Hydrogen Reduces Electromagnetic Pulse-Induced Male Rat Reproductive System Damage in a Rodent Model.
Ma L, Hao W, Feng WB, Cao LC, Qin LN, Wang Y, Liu MH, Wang NZ, Gao F, Guo JM, Du H, Yan HL
Oxidative medicine and cellular longevity 2022;2022:3469474
Oxidative medicine and cellular longevity 2022;2022:3469474
Mulberry Leaf Flavonoids Inhibit Liver Inflammation in Type 2 Diabetes Rats by Regulating TLR4/MyD88/NF-κB Signaling Pathway.
Duan Y, Dai H, An Y, Cheng L, Shi L, Lv Y, Li H, Wang C, He C, Zhang H, Huang Y, Fu W, Meng Y, Zhao B
Evidence-based complementary and alternative medicine : eCAM 2022;2022:3354062
Evidence-based complementary and alternative medicine : eCAM 2022;2022:3354062
Theaflavin-3,3'-Digallate Protects Cartilage from Degradation by Modulating Inflammation and Antioxidant Pathways.
Teng Y, Jin Z, Ren W, Lu M, Hou M, Zhou Q, Wang W, Yang H, Zou J
Oxidative medicine and cellular longevity 2022;2022:3047425
Oxidative medicine and cellular longevity 2022;2022:3047425
San-Huang-Yi-Shen Capsule Ameliorates Diabetic Kidney Disease through Inducing PINK1/Parkin-Mediated Mitophagy and Inhibiting the Activation of NLRP3 Signaling Pathway.
Li H, Wang Y, Su X, Wang Q, Zhang S, Sun W, Zhang T, Dong M, Zhang Z, Lv S
Journal of diabetes research 2022;2022:2640209
Journal of diabetes research 2022;2022:2640209
Grape Seed Proanthocyanidins Exert a Neuroprotective Effect by Regulating Microglial M1/M2 Polarisation in Rats with Spinal Cord Injury.
Liu WZ, Ma ZJ, Kang JH, Lin AX, Wang ZH, Chen HW, Guo XD, He XG, Kang XW
Mediators of inflammation 2022;2022:2579003
Mediators of inflammation 2022;2022:2579003
β-Carotene Attenuates Apoptosis and Autophagy via PI3K/AKT/mTOR Signaling Pathway in Necrotizing Enterocolitis Model Cells IEC-6.
Xu G, Ma T, Zhou C, Zhao F, Peng K, Li B
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2502263
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2502263
Geraniin Protects against Cerebral Ischemia/Reperfusion Injury by Suppressing Oxidative Stress and Neuronal Apoptosis via Regulation of the Nrf2/HO-1 Pathway.
Yang Y, He B, Zhang X, Yang R, Xia X, Chen L, Li R, Shen Z, Chen P
Oxidative medicine and cellular longevity 2022;2022:2152746
Oxidative medicine and cellular longevity 2022;2022:2152746
Identification and Validation of a Prognostic Signature Based on Methylation Profiles and Methylation-Driven Gene DAB2 as a Prognostic Biomarker in Differentiated Thyroid Carcinoma.
Ju G, Zhang L, Guo W, Wang H, Zhang X, Mu Z, Sun Y, Sun D, Diao H, Miao S, Chen Y, Xing T, Liang J, Lin Y
Disease markers 2022;2022:1686316
Disease markers 2022;2022:1686316
Diet-Induced High Serum Levels of Trimethylamine-N-oxide Enhance the Cellular Inflammatory Response without Exacerbating Acute Intracerebral Hemorrhage Injury in Mice.
Li C, Zhu L, Dai Y, Zhang Z, Huang L, Wang TJ, Fu P, Li Y, Wang J, Jiang C
Oxidative medicine and cellular longevity 2022;2022:1599747
Oxidative medicine and cellular longevity 2022;2022:1599747
Maternal Inflammation Exaggerates Offspring Susceptibility to Cerebral Ischemia-Reperfusion Injury via the COX-2/PGD2/DP(2) Pathway Activation.
Li Y, Luo W, Zhang J, Luo Y, Han W, Wang H, Xia H, Chen Z, Yang Y, Chen Q, Li H, Yang L, Hu C, Huang H, Peng Z, Tan X, Li M, Yang J
Oxidative medicine and cellular longevity 2022;2022:1571705
Oxidative medicine and cellular longevity 2022;2022:1571705
Liensinine Inhibits Cell Growth and Blocks Autophagic Flux in Nonsmall-Cell Lung Cancer.
Chang M, Ding S, Dong X, Shang X, Li Y, Xie L, Song X, Song X
Journal of oncology 2022;2022:1533779
Journal of oncology 2022;2022:1533779
Acupuncture Effect Assessment in APP/PS1 Transgenic Mice: On Regulating Learning-Memory Abilities, Gut Microbiota, and Microbial Metabolites.
Yang B, He M, Chen X, Sun M, Pan T, Xu X, Zhang X, Gong Q, Zhao Y, Jin Z, Cheng Z
Computational and mathematical methods in medicine 2022;2022:1527159
Computational and mathematical methods in medicine 2022;2022:1527159
Maltol Promotes Mitophagy and Inhibits Oxidative Stress via the Nrf2/PINK1/Parkin Pathway after Spinal Cord Injury.
Mao Y, Du J, Chen X, Al Mamun A, Cao L, Yang Y, Mubwandarikwa J, Zaeem M, Zhang W, Chen Y, Dai Y, Xiao J, Ye K
Oxidative medicine and cellular longevity 2022;2022:1337630
Oxidative medicine and cellular longevity 2022;2022:1337630
Xiao-Chai-Hu Decoction Ameliorates Poly (I:C)-Induced Viral Pneumonia through Inhibiting Inflammatory Response and Modulating Serum Metabolism.
Chen F, Qu F, Jia Y, Wang C, Yu Y, Liao J, Lin M, Chen F, Sun Z
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1240242
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1240242
Altered gene expression in human brain microvascular endothelial cells in response to the infection of influenza H1N1 virus.
Higazy D, Lin X, Xie T, Wang K, Gao X, Cui M
Animal diseases 2022;2(1):25
Animal diseases 2022;2(1):25
High-mobility Group Box 1 Contributes to Hypoxic-Ischemic Brain Damage by Facilitating Imbalance of Microglial Polarization through RAGE-PI3K/Akt Pathway in Neonatal Rats.
Sun Y, Zhu X, Zhu K, Yu J, Cheng L, Hei M
International journal of medical sciences 2022;19(14):2093-2103
International journal of medical sciences 2022;19(14):2093-2103
A marine-derived small molecule induces immunogenic cell death against triple-negative breast cancer through ER stress-CHOP pathway.
Wen H, Zhong Y, Yin Y, Qin K, Yang L, Li D, Yu W, Yang C, Deng Z, Hong K
International journal of biological sciences 2022;18(7):2898-2913
International journal of biological sciences 2022;18(7):2898-2913
BMAL1 regulates Propionibacterium acnes-induced skin inflammation via REV-ERBα in mice.
Li F, Lin L, He Y, Sun G, Dong D, Wu B
International journal of biological sciences 2022;18(6):2597-2608
International journal of biological sciences 2022;18(6):2597-2608
Low expression of microRNA-125b enhances the expression of STAT3 and contributes to cholesteatoma growth.
Zang J, Yang B, Feng S, Jiang X
Archives of medical science : AMS 2022;18(6):1596-1606
Archives of medical science : AMS 2022;18(6):1596-1606
RBMS2 Chemosensitizes Breast Cancer Cells to Doxorubicin by Regulating BMF Expression.
Xu F, Xia T, Xu QT, Zhang X, Huang YZ, Sun X, Shi L, Zhou XJ, Wei JF, Ding Q
International journal of biological sciences 2022;18(4):1724-1736
International journal of biological sciences 2022;18(4):1724-1736
The lncRNA BDNF-AS/WDR5/FBXW7 axis mediates ferroptosis in gastric cancer peritoneal metastasis by regulating VDAC3 ubiquitination.
Huang G, Xiang Z, Wu H, He Q, Dou R, Lin Z, Yang C, Huang S, Song J, Di Z, Wang S, Xiong B
International journal of biological sciences 2022;18(4):1415-1433
International journal of biological sciences 2022;18(4):1415-1433
HJURP Promotes Malignant Progression and Mediates Sensitivity to Cisplatin and WEE1-inhibitor in Serous Ovarian Cancer.
Dou Z, Qiu C, Zhang X, Yao S, Zhao C, Wang Z, Chu R, Chen J, Chen Z, Li R, Wang K, Liu P, Liu C, Song K, Kong B
International journal of biological sciences 2022;18(3):1188-1210
International journal of biological sciences 2022;18(3):1188-1210
HNRNPK/CLCN3 axis facilitates the progression of LUAD through CAF-tumor interaction.
Li Y, Yang Y, Ma Q, Cheng H, Wang H, Ma C, Li F, Zhao S, Li X, Qi Y, Gu Z
International journal of biological sciences 2022;18(16):6084-6101
International journal of biological sciences 2022;18(16):6084-6101
Anp32e promotes renal interstitial fibrosis by upregulating the expression of fibrosis-related proteins.
Wei J, Shan Y, Xiao Z, Wen L, Tao Y, Fang X, Luo H, Tang C, Li Y
International journal of biological sciences 2022;18(15):5897-5912
International journal of biological sciences 2022;18(15):5897-5912
Psychosocial stress and cannabinoid drugs affect acetylation of α-tubulin (K40) and gene expression in the prefrontal cortex of adult mice.
Tomas-Roig J, Ramasamy S, Zbarsky D, Havemann-Reinecke U, Hoyer-Fender S
PloS one 2022;17(9):e0274352
PloS one 2022;17(9):e0274352
Decitabine attenuates ischemic stroke by reducing astrocytes proliferation in rats.
Zhang Q, Li D, Zhao H, Zhang X
PloS one 2022;17(8):e0272482
PloS one 2022;17(8):e0272482
RETRACTED: Zoledronic acid generates a spatiotemporal effect to attenuate osteoarthritis by inhibiting potential Wnt5a-associated abnormal subchondral bone resorption.
Ding D, Wang L, Yan J, Zhou Y, Feng G, Ma L, Yang Y, Pei X, Jin Q
PloS one 2022;17(7):e0271485
PloS one 2022;17(7):e0271485
Concomitant pyroptotic and apoptotic cell death triggered in macrophages infected by Zika virus.
Wen C, Yu Y, Gao C, Qi X, Cardona CJ, Xing Z
PloS one 2022;17(4):e0257408
PloS one 2022;17(4):e0257408
Gut microbiota and butyrate contribute to nonalcoholic fatty liver disease in premenopause due to estrogen deficiency.
Liu L, Fu Q, Li T, Shao K, Zhu X, Cong Y, Zhao X
PloS one 2022;17(2):e0262855
PloS one 2022;17(2):e0262855
Alzheimer's risk factor FERMT2 promotes the progression of colorectal carcinoma via Wnt/β-catenin signaling pathway and contributes to the negative correlation between Alzheimer and cancer.
Xia W, Gao Z, Jiang X, Jiang L, Qin Y, Zhang D, Tian P, Wang W, Zhang Q, Zhang R, Zhang N, Xu S
PloS one 2022;17(12):e0278774
PloS one 2022;17(12):e0278774
miR-186-5p Dysregulation in Serum Exosomes from Patients with AMI Aggravates Atherosclerosis via Targeting LOX-1.
Ding J, Li H, Liu W, Wang X, Feng Y, Guan H, Chen Z
International journal of nanomedicine 2022;17:6301-6316
International journal of nanomedicine 2022;17:6301-6316
The neural stem cell properties of Pkd2l1(+) cerebrospinal fluid-contacting neurons in vivo.
Cao L, Huang MZ, Zhang Q, Luo ZR, Zhang Y, An PJ, Yang LL, Tan W, Wang CQ, Dou XW, Li Q
Frontiers in cellular neuroscience 2022;16:992520
Frontiers in cellular neuroscience 2022;16:992520
Decreased tubulin-binding cofactor B was involved in the formation disorder of nascent astrocyte processes by regulating microtubule plus-end growth through binding with end-binding proteins 1 and 3 after chronic alcohol exposure.
Zheng Y, Yang M, Chen X, Zhang G, Wan S, Zhang B, Huo J, Liu H
Frontiers in cellular neuroscience 2022;16:989945
Frontiers in cellular neuroscience 2022;16:989945
Identification of key genes and pathways revealing the central regulatory mechanism of brain-derived glucagon-like peptide-1 on obesity using bioinformatics analysis.
Shao Y, Tian J, Yang Y, Hu Y, Zhu Y, Shu Q
Frontiers in neuroscience 2022;16:931161
Frontiers in neuroscience 2022;16:931161
Ketamine Attenuates Airway Inflammation via Inducing Inflammatory Cells Apoptosis and Activating Nrf2 Pathway in a Mixed-Granulocytic Murine Asthma Model.
Xiao S, Zhou Y, Wang Q, Yang D
Drug design, development and therapy 2022;16:4411-4428
Drug design, development and therapy 2022;16:4411-4428
Canagliflozin Attenuates Hepatic Steatosis and Atherosclerosis Progression in Western Diet-Fed ApoE-Knockout Mice.
Zuo Q, Zhang G, He L, Ma S, Ma H, Zhai J, Wang Z, Zhang T, Wang Y, Guo Y
Drug design, development and therapy 2022;16:4161-4177
Drug design, development and therapy 2022;16:4161-4177
Feasibility of Catalpol Intranasal Administration and Its Protective Effect on Acute Cerebral Ischemia in Rats via Anti-Oxidative and Anti-Apoptotic Mechanisms.
Wang J, Zhang Y, Zhang M, Sun S, Zhong Y, Han L, Xu Y, Wan D, Zhang J, Zhu H
Drug design, development and therapy 2022;16:279-296
Drug design, development and therapy 2022;16:279-296
Analysis of the expression and distribution of protein O-linked mannose β1,2-N-acetylglucosaminyltransferase 1 in the normal adult mouse brain.
Jiang H, Feng Y, He G, Liu Y, Li X
Frontiers in neuroanatomy 2022;16:1043924
Frontiers in neuroanatomy 2022;16:1043924
The Effect and Mechanism of Duodenal-Jejunal Bypass to Treat Type 2 Diabetes Mellitus in a Rat Model.
Chen X, Zhang Q, Yang Q, Huang Z, Liao G, Wang Z
Obesity facts 2022;15(3):344-356
Obesity facts 2022;15(3):344-356
Ras-related protein Rab-20 inhibition alleviates cerebral ischemia/reperfusion injury by inhibiting mitochondrial fission and dysfunction.
Guo J, Zhang L, Bu Y, Li W, Hu J, Li J
Frontiers in molecular neuroscience 2022;15:986710
Frontiers in molecular neuroscience 2022;15:986710
Genetic Deficiency of p53 Leads to Structural, Functional, and Synaptic Deficits in Primary Somatosensory Cortical Neurons of Adult Mice.
Kuang H, Liu T, Jiao C, Wang J, Wu S, Wu J, Peng S, Davidson AM, Zeng SX, Lu H, Mostany R
Frontiers in molecular neuroscience 2022;15:871974
Frontiers in molecular neuroscience 2022;15:871974
Receptor-Interacting Protein Kinase 3 Inhibition Relieves Mechanical Allodynia and Suppresses NLRP3 Inflammasome and NF-κB in a Rat Model of Spinal Cord Injury.
Xue S, Cao ZX, Wang JN, Zhao QX, Han J, Yang WJ, Sun T
Frontiers in molecular neuroscience 2022;15:861312
Frontiers in molecular neuroscience 2022;15:861312
NF-κB and AP-1 are required for the lipopolysaccharide-induced expression of MCP-1, CXCL1, and Cx43 in cultured rat dorsal spinal cord astrocytes.
Lu Y, Li B, Xu A, Liang X, Xu T, Jin H, Xie Y, Wang R, Liu X, Gao X, Han Y, Zeng J
Frontiers in molecular neuroscience 2022;15:859558
Frontiers in molecular neuroscience 2022;15:859558
Apelin-13 Attenuates Lipopolysaccharide-Induced Inflammatory Responses and Acute Lung Injury by Regulating PFKFB3-Driven Glycolysis Induced by NOX4-Dependent ROS.
Yuan Y, Wang W, Zhang Y, Hong Q, Huang W, Li L, Xie Z, Chen Y, Li X, Meng Y
Journal of inflammation research 2022;15:2121-2139
Journal of inflammation research 2022;15:2121-2139
The inhibition of PGAM5 suppresses seizures in a kainate-induced epilepsy model via mitophagy reduction.
Zhong F, Gan Y, Song J, Zhang W, Yuan S, Qin Z, Wu J, Lü Y, Yu W
Frontiers in molecular neuroscience 2022;15:1047801
Frontiers in molecular neuroscience 2022;15:1047801
Involvement of hedgehog signaling in all-trans retinoic acid-mediated suppression of colon cancer.
Xu Y, Sun H
American journal of translational research 2022;14(9):6536-6549
American journal of translational research 2022;14(9):6536-6549
miR-153-3p inhibits osteogenic differentiation of BMSCs by down-regulating the expression of RUNX2 in a high glucose environment.
Wang Q, Xia Q, Meng M, Li Y, Tang Z, Zeng X, Chen H, Shu J, Xv X, Chen J, Lu J, Wang H, Ye Z, Song B, Dong Q
American journal of translational research 2022;14(10):7027-7039
American journal of translational research 2022;14(10):7027-7039
Macrophage SCAP Contributes to Metaflammation and Lean NAFLD by Activating STING-NF-κB Signaling Pathway.
Huang X, Yao Y, Hou X, Wei L, Rao Y, Su Y, Zheng G, Ruan XZ, Li D, Chen Y
Cellular and molecular gastroenterology and hepatology 2022;14(1):1-26
Cellular and molecular gastroenterology and hepatology 2022;14(1):1-26
KLF16 Downregulates the Expression of Tumor Suppressor Gene TGFBR3 to Promote Bladder Cancer Proliferation and Migration.
Chen X, Wang P, Ou T, Li J
Cancer management and research 2022;14:465-477
Cancer management and research 2022;14:465-477
Effect of β-hydroxybutyrate on behavioral alterations, molecular and morphological changes in CNS of multiple sclerosis mouse model.
Sun W, Wen M, Liu M, Wang Q, Liu Q, Li L, Siebert HC, Loers G, Zhang R, Zhang N
Frontiers in aging neuroscience 2022;14:1075161
Frontiers in aging neuroscience 2022;14:1075161
1,25-D3 attenuates cerebral ischemia injury by regulating mitochondrial metabolism via the AMPK/AKT/GSK3β pathway.
Li Y, Li X, Xu S, Zhao Y, Pang M, Zhang X, Wang X, Wang Y
Frontiers in aging neuroscience 2022;14:1015453
Frontiers in aging neuroscience 2022;14:1015453
Impact prediction of translocation of the mitochondrial outer membrane 70 as biomarker in Alzheimer's disease.
Cao X, Chen Y, Sang X, Xu S, Xie Z, Zhu Z, Wang P, Bi J, Xu L
Frontiers in aging neuroscience 2022;14:1013943
Frontiers in aging neuroscience 2022;14:1013943
Transcriptional and H3K27ac related genome profiles in oral squamous cell carcinoma cells treated with metformin.
Liu S, Shi C, Hou X, Tian X, Li C, Ma X, Wang X, Gao P
Journal of Cancer 2022;13(6):1859-1870
Journal of Cancer 2022;13(6):1859-1870
Silencing LINC00491 Inhibits Pancreatic Cancer Progression through MiR-188-5p-induced Inhibition of ZFP91.
Fang Z, Ruan B, Zhong M, Xiong J, Jiang Y, Song Z
Journal of Cancer 2022;13(6):1808-1819
Journal of Cancer 2022;13(6):1808-1819
Sinapine Thiocyanate Inhibits the Proliferation and Mobility of Pancreatic Cancer Cells by Up-Regulating GADD45A.
Wang J, Zeng Z, Lei S, Han J, Liao S, Zhang J, Wang L, Dong Y, Li H, Chen T
Journal of Cancer 2022;13(4):1229-1240
Journal of Cancer 2022;13(4):1229-1240
Niban apoptosis regulator 1 promotes gemcitabine resistance by activating the focal adhesion kinase signaling pathway in bladder cancer.
Tong S, Yin H, Fu J, Li Y
Journal of Cancer 2022;13(4):1103-1118
Journal of Cancer 2022;13(4):1103-1118
PERK Regulates the Sensitivity of Hepatocellular Carcinoma Cells to High-LET Carbon Ions via either Apoptosis or Ferroptosis.
Zheng X, Liu B, Liu X, Li P, Zhang P, Ye F, Zhao T, Kuang Y, Chen W, Jin X, Li Q
Journal of Cancer 2022;13(2):669-680
Journal of Cancer 2022;13(2):669-680
LHPP suppresses gastric cancer progression via the PI3K/AKT/mTOR signaling pathway.
Wang D, Li J, Li W
Journal of Cancer 2022;13(14):3584-3592
Journal of Cancer 2022;13(14):3584-3592
Analysis of the absorbed constituents and mechanism of liquidambaris fructus extract on hepatocellular carcinoma.
Wang S, Yang XX, Li TJ, Zhao L, Bao YR, Meng XS
Frontiers in pharmacology 2022;13:999935
Frontiers in pharmacology 2022;13:999935
CaM/CaMKII mediates activation and proliferation of hepatic stellate cells regulated by ASIC1a.
Liu H, Lu WL, Hong HQ, Li MJ, Ye MP, Rao QF, Kong JL, Luan SH, Huang Y, Hu QH, Wu FR
Frontiers in pharmacology 2022;13:996667
Frontiers in pharmacology 2022;13:996667
A prognostic signature consisting of metabolism-related genes and SLC17A4 serves as a potential biomarker of immunotherapeutic prediction in prostate cancer.
Li H, Gu J, Tian Y, Li S, Zhang H, Dai Z, Wang Z, Zhang N, Peng R
Frontiers in immunology 2022;13:982628
Frontiers in immunology 2022;13:982628
Bu-Gu-Sheng-Sui decoction promotes osteogenesis via activating the ERK/Smad signaling pathways.
Liu N, Qi B, Zhang Y, Fang S, Sun C, Li Q, Wei X
Frontiers in pharmacology 2022;13:976121
Frontiers in pharmacology 2022;13:976121
Alleviating effect of quercetin on cadmium-induced oxidative damage and apoptosis by activating the Nrf2-keap1 pathway in BRL-3A cells.
Wang J, Wang K, Ding L, Zhao P, Zhang C, Wang H, Yang Z, Liu Z
Frontiers in pharmacology 2022;13:969892
Frontiers in pharmacology 2022;13:969892
Paeoniflorin directly binds to TNFR1 to regulate podocyte necroptosis in diabetic kidney disease.
Wang X, Liu XQ, Jiang L, Huang YB, Zeng HX, Zhu QJ, Qi XM, Wu YG
Frontiers in pharmacology 2022;13:966645
Frontiers in pharmacology 2022;13:966645
Inhibition of calpain9 attenuates peritoneal dialysis-related peritoneal fibrosis.
Li F, Wang Y, Tian J, Zhou Z, Yin W, Qin X, Wang H, Zeng T, Li A, Jiang J
Frontiers in pharmacology 2022;13:962770
Frontiers in pharmacology 2022;13:962770
Reduced binding activity of vaccine serum to omicron receptor-binding domain.
Li M, Weng S, Wang Q, Yang Z, Wang X, Yin Y, Zhou Q, Zhang L, Tao F, Li Y, Jia M, Yang L, Xin X, Li H, Kang L, Wang Y, Wang T, Li S, Kong L
Frontiers in immunology 2022;13:960195
Frontiers in immunology 2022;13:960195
Sanguinarine protects against indomethacin-induced small intestine injury in rats by regulating the Nrf2/NF-κB pathways.
Lin XL, Shi YN, Cao YL, Tan X, Zeng YL, Luo ST, Li YM, Qin L, Xia BH, Fu RG, Lin LM, Li K, Cao D, Zeng JG, Liao DF
Frontiers in pharmacology 2022;13:960140
Frontiers in pharmacology 2022;13:960140
Poldip2 knockdown protects against lipopolysaccharide-induced acute lung injury via Nox4/Nrf2/NF-κB signaling pathway.
Wang Y, Wang W, Zhou S, Wang Y, Cudjoe O, Cha Y, Wang C, Cao X, Liu W, Jin K
Frontiers in pharmacology 2022;13:958916
Frontiers in pharmacology 2022;13:958916
Construction, bioinformatics analysis, and validation of competitive endogenous RNA networks in ulcerative colitis.
Dong L, Zhang R, Huang Q, Shen Y, Li H, Yu S, Wu Q
Frontiers in genetics 2022;13:951243
Frontiers in genetics 2022;13:951243
Puffball spores improve wound healing in a diabetic rat model.
He T, Sun P, Liu B, Wan S, Fang P, Chen J, Huang G, Min W
Frontiers in endocrinology 2022;13:942549
Frontiers in endocrinology 2022;13:942549
Identifying potential prognosis markers in hepatocellular carcinoma via integrated bioinformatics analysis and biological experiments.
Hu X, Zhou J, Zhang Y, Zeng Y, Jie G, Wang S, Yang A, Zhang M
Frontiers in genetics 2022;13:942454
Frontiers in genetics 2022;13:942454
Melatonin promotes sirtuin 1 expression and inhibits IRE1α-XBP1S-CHOP to reduce endoplasmic reticulum stress-mediated apoptosis in chondrocytes.
Qin K, Tang H, Ren Y, Yang D, Li Y, Huang W, Wu Y, Yin Z
Frontiers in pharmacology 2022;13:940629
Frontiers in pharmacology 2022;13:940629
Ferredoxin 1 is a cuproptosis-key gene responsible for tumor immunity and drug sensitivity: A pan-cancer analysis.
Yang L, Zhang Y, Wang Y, Jiang P, Liu F, Feng N
Frontiers in pharmacology 2022;13:938134
Frontiers in pharmacology 2022;13:938134
Polysaccharide, the Active Component of Dendrobium officinale, Ameliorates Metabolic Hypertension in Rats via Regulating Intestinal Flora-SCFAs-Vascular Axis.
Li B, Wang HY, Huang JH, Xu WF, Feng XJ, Xiong ZP, Dong YJ, Li LZ, He X, Wu HS, Zhang K, Su J, Yu QX, Jiang NH, Lv GY, Chen SH
Frontiers in pharmacology 2022;13:935714
Frontiers in pharmacology 2022;13:935714
Identification of oncogenes and tumor-suppressor genes with hepatocellular carcinoma: A comprehensive analysis based on TCGA and GEO datasets.
Zhu Y, Wang Y, Hu M, Lu X, Sun G
Frontiers in genetics 2022;13:934883
Frontiers in genetics 2022;13:934883
D-tagatose protects against oleic acid-induced acute respiratory distress syndrome in rats by activating PTEN/PI3K/AKT pathway.
Huang J, Wang B, Tao S, Hu Y, Wang N, Zhang Q, Wang C, Chen C, Gao B, Cheng X, Li Y
Frontiers in immunology 2022;13:928312
Frontiers in immunology 2022;13:928312
Acetyl-11-Keto-Beta Boswellic Acid (AKBA) Protects Lens Epithelial Cells Against H(2)O(2)-Induced Oxidative Injury and Attenuates Cataract Progression by Activating Keap1/Nrf2/HO-1 Signaling.
Yang T, Lin X, Li H, Zhou X, Fan F, Yang J, Luo Y, Liu X
Frontiers in pharmacology 2022;13:927871
Frontiers in pharmacology 2022;13:927871
Protective effect of Astragaloside IV on chronic intermittent hypoxia-induced vascular endothelial dysfunction through the calpain-1/SIRT1/AMPK signaling pathway.
Zhao F, Meng Y, Wang Y, Fan S, Liu Y, Zhang X, Ran C, Wang H, Lu M
Frontiers in pharmacology 2022;13:920977
Frontiers in pharmacology 2022;13:920977
β-elemene Isopropanolamine Derivative LXX-8250 Induces Apoptosis Through Impairing Autophagic Flux via PFKFB4 Repression in Melanoma Cells.
Jalal S, Zhang T, Deng J, Wang J, Xu T, Zhang T, Zhai C, Yuan R, Teng H, Huang L
Frontiers in pharmacology 2022;13:900973
Frontiers in pharmacology 2022;13:900973
EspF of Enterohemorrhagic Escherichia coli Enhances Apoptosis via Endoplasmic Reticulum Stress in Intestinal Epithelial Cells: An Isobaric Tags for Relative and Absolute Quantitation-Based Comparative Proteomic Analysis.
Wang X, Yan K, Fu M, Liang S, Zhao H, Fu C, Yang L, Song Z, Sun D, Wan C
Frontiers in microbiology 2022;13:900919
Frontiers in microbiology 2022;13:900919
Chronic constant light exposure aggravates high fat diet-induced renal injury in rats.
Xing L, Wu S, Shi Y, Yue F, Wei L, Russell R, Zhang D
Frontiers in endocrinology 2022;13:900392
Frontiers in endocrinology 2022;13:900392
Evaluation of decompressive craniectomy in mice after severe traumatic brain injury.
Liu Y, Liu X, Chen Z, Wang Y, Li J, Gong J, He A, Zhao M, Yang C, Yang W, Wang Z
Frontiers in neurology 2022;13:898813
Frontiers in neurology 2022;13:898813
Olanzapine-induced lipid disturbances: A potential mechanism through the gut microbiota-brain axis.
Zhu Z, Gu Y, Zeng C, Yang M, Yu H, Chen H, Zhang B, Cai H
Frontiers in pharmacology 2022;13:897926
Frontiers in pharmacology 2022;13:897926
Interleukin-6-derived cancer-associated fibroblasts activate STAT3 pathway contributing to gemcitabine resistance in cholangiocarcinoma.
Kittirat Y, Suksawat M, Thongchot S, Padthaisong S, Phetcharaburanin J, Wangwiwatsin A, Klanrit P, Sangkhamanon S, Titapun A, Loilome W, Saya H, Namwat N
Frontiers in pharmacology 2022;13:897368
Frontiers in pharmacology 2022;13:897368
Melatonin prevents cyclophosphamide-induced primordial follicle loss by inhibiting ovarian granulosa cell apoptosis and maintaining AMH expression.
Feng J, Ma WW, Li HX, Pei XY, Deng SL, Jia H, Ma WZ
Frontiers in endocrinology 2022;13:895095
Frontiers in endocrinology 2022;13:895095
Optineurin-mediated mitophagy as a potential therapeutic target for intervertebral disc degeneration.
Hu Z, Wang Y, Gao X, Zhang Y, Liu C, Zhai Y, Chang X, Li H, Li Y, Lou J, Li C
Frontiers in pharmacology 2022;13:893307
Frontiers in pharmacology 2022;13:893307
Phyllanthus Niruri L. Exerts Protective Effects Against the Calcium Oxalate-Induced Renal Injury via Ellgic Acid.
Li MT, Liu LL, Zhou Q, Huang LX, Shi YX, Hou JB, Lu HT, Yu B, Chen W, Guo ZY
Frontiers in pharmacology 2022;13:891788
Frontiers in pharmacology 2022;13:891788
High expression of B4GALT1 is associated with poor prognosis in acute myeloid leukemia.
Ren Z, Huang X, Lv Q, Lei Y, Shi H, Wang F, Wang M
Frontiers in genetics 2022;13:882004
Frontiers in genetics 2022;13:882004
Pan-Cancer Analysis of the Immunological Role of PDIA5: A Potential Target for Immunotherapy.
Chen Y, He J, Chen R, Wang Z, Dai Z, Liang X, Wu W, Luo P, Zhang J, Peng Y, Zhang N, Liu Z, Zhang L, Zhang H, Cheng Q
Frontiers in immunology 2022;13:881722
Frontiers in immunology 2022;13:881722
Novel Antiviral Activity of Ethyl 3-Hydroxyhexanoate Against Coxsackievirus B Infection.
Olasunkanmi OI, Mageto J, Avala Ntsigouaye J, Yi M, Fei Y, Chen Y, Chen S, Xu W, Lin L, Zhao W, Wang Y, Zhong ZH
Frontiers in microbiology 2022;13:875485
Frontiers in microbiology 2022;13:875485
Liraglutide Attenuates Hepatic Ischemia-Reperfusion Injury by Modulating Macrophage Polarization.
Li SL, Wang ZM, Xu C, Che FH, Hu XF, Cao R, Xie YN, Qiu Y, Shi HB, Liu B, Dai C, Yang J
Frontiers in immunology 2022;13:869050
Frontiers in immunology 2022;13:869050
Arachidonic Acid in Follicular Fluid of PCOS Induces Oxidative Stress in a Human Ovarian Granulosa Tumor Cell Line (KGN) and Upregulates GDF15 Expression as a Response.
Ma Y, Zheng L, Wang Y, Gao Y, Xu Y
Frontiers in endocrinology 2022;13:865748
Frontiers in endocrinology 2022;13:865748
Effects of Xiao Chengqi Formula on Slow Transit Constipation by Assessing Gut Microbiota and Metabolomics Analysis in vitro and in vivo.
Zhou Q, Zhang D, Zhang H, Wan X, Hu B, Zou Q, Su D, Peng H, Huang D, Ren D
Frontiers in pharmacology 2022;13:864598
Frontiers in pharmacology 2022;13:864598
MiR-103a-3p Promotes Zika Virus Replication by Targeting OTU Deubiquitinase 4 to Activate p38 Mitogen-Activated Protein Kinase Signaling Pathway.
Ye H, Kang L, Yan X, Li S, Huang Y, Mu R, Duan X, Chen L
Frontiers in microbiology 2022;13:862580
Frontiers in microbiology 2022;13:862580
Identification of cytochrome c oxidase subunit 4 isoform 1 as a positive regulator of influenza virus replication.
He J, Huang H, Li B, Li H, Zhao Y, Li Y, Ye W, Qi W, Tang W, Wang L
Frontiers in microbiology 2022;13:862205
Frontiers in microbiology 2022;13:862205
Comprehensive Analysis of the Potential Immune-Related Biomarker ATG101 that Regulates Apoptosis of Cholangiocarcinoma Cells After Photodynamic Therapy.
Zhang ZJ, Wang KP, Huang YP, Jin C, Jiang H, Xiong L, Chen ZY, Wen Y, Liu ZT, Mo JG
Frontiers in pharmacology 2022;13:857774
Frontiers in pharmacology 2022;13:857774
Kaempferol From Penthorum chinense Pursh Attenuates Hepatic Ischemia/Reperfusion Injury by Suppressing Oxidative Stress and Inflammation Through Activation of the Nrf2/HO-1 Signaling Pathway.
Chen Y, Li T, Tan P, Shi H, Cheng Y, Cai T, Bai J, Du Y, Fu W
Frontiers in pharmacology 2022;13:857015
Frontiers in pharmacology 2022;13:857015
Munronoid I Ameliorates DSS-Induced Mouse Colitis by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis Via Modulation of NLRP3.
Ma X, Di Q, Li X, Zhao X, Zhang R, Xiao Y, Li X, Wu H, Tang H, Quan J, Wu Z, Xiao W, Chen W
Frontiers in immunology 2022;13:853194
Frontiers in immunology 2022;13:853194
Quercetin Attenuates Osteoporosis in Orchiectomy Mice by Regulating Glucose and Lipid Metabolism via the GPRC6A/AMPK/mTOR Signaling Pathway.
Sun J, Pan Y, Li X, Wang L, Liu M, Tu P, Wu C, Xiao J, Han Q, Da W, Ma Y, Guo Y
Frontiers in endocrinology 2022;13:849544
Frontiers in endocrinology 2022;13:849544
Vitamin D Deficiency Impacts Exposure and Response of Pravastatin in Male Rats by Altering Hepatic OATPs.
Peng J, Yang G, Huang Z
Frontiers in pharmacology 2022;13:841954
Frontiers in pharmacology 2022;13:841954
Heat Stress Modulates a Placental Immune Response Associated With Alterations in the Development of the Fetal Intestine and Its Innate Immune System in Late Pregnant Mouse.
Guo H, Liu R, He J, Yao W, Zheng W
Frontiers in physiology 2022;13:841149
Frontiers in physiology 2022;13:841149
Identification of an autophagy-related 12-lncRNA signature and evaluation of NFYC-AS1 as a pro-cancer factor in lung adenocarcinoma.
Tong F, Xu L, Xu S, Zhang M
Frontiers in genetics 2022;13:834935
Frontiers in genetics 2022;13:834935
Trans-Anethole Alleviates Subclinical Necro-Haemorrhagic Enteritis-Induced Intestinal Barrier Dysfunction and Intestinal Inflammation in Broilers.
Yu C, Wang D, Tong Y, Li Q, Yang W, Wang T, Yang Z
Frontiers in microbiology 2022;13:831882
Frontiers in microbiology 2022;13:831882
Dehydrocostus Lactone Suppresses Dextran Sulfate Sodium-Induced Colitis by Targeting the IKKα/β-NF-κB and Keap1-Nrf2 Signalling Pathways.
Yuan Y, Hu Q, Liu L, Xie F, Yang L, Li Y, Zhang C, Chen H, Tang J, Shen X
Frontiers in pharmacology 2022;13:817596
Frontiers in pharmacology 2022;13:817596
Didymin Suppresses Microglia Pyroptosis and Neuroinflammation Through the Asc/Caspase-1/GSDMD Pathway Following Experimental Intracerebral Hemorrhage.
Gu L, Sun M, Li R, Zhang X, Tao Y, Yuan Y, Luo X, Xie Z
Frontiers in immunology 2022;13:810582
Frontiers in immunology 2022;13:810582
Avasimibe Alleviates Disruption of the Airway Epithelial Barrier by Suppressing the Wnt/β-Catenin Signaling Pathway.
Zhou Z, Liang S, Zhou Z, Liu J, Meng X, Zou F, Yu C, Cai S
Frontiers in pharmacology 2022;13:795934
Frontiers in pharmacology 2022;13:795934
Long Noncoding RNA Metastasis-Associated Lung Adenocarcinoma Transcript 1 in Extracellular Vesicles Promotes Hepatic Stellate Cell Activation, Liver Fibrosis and β-Catenin Signaling Pathway.
Wang T, Zhang C, Meng X, Zhu B, Wang S, Yuan W, Zhang S, Xu J, Zhang C
Frontiers in physiology 2022;13:792182
Frontiers in physiology 2022;13:792182
Chemerin Regulates the Proliferation and Migration of Pulmonary Arterial Smooth Muscle Cells via the ERK1/2 Signaling Pathway.
Peng L, Chen Y, Li Y, Feng P, Zheng Y, Dong Y, Yang Y, Wang R, Li A, Yan J, Shang F, Tang P, Chen D, Gao Y, Huang W
Frontiers in pharmacology 2022;13:767705
Frontiers in pharmacology 2022;13:767705
Alpha-Asaronol Alleviates Dysmyelination by Enhancing Glutamate Transport Through the Activation of PPARγ-GLT-1 Signaling in Hypoxia-Ischemia Neonatal Rats.
Ge Y, Zhen F, Liu Z, Feng Z, Wang G, Zhang C, Wang X, Sun Y, Zheng X, Bai Y, Yao R
Frontiers in pharmacology 2022;13:766744
Frontiers in pharmacology 2022;13:766744
Pectin supplement alleviates gut injury potentially through improving gut microbiota community in piglets.
Dang G, Wang W, Zhong R, Wu W, Chen L, Zhang H
Frontiers in microbiology 2022;13:1069694
Frontiers in microbiology 2022;13:1069694
A positive feedback loop of the TAZ/β-catenin axis promotes Helicobacter pylori-associated gastric carcinogenesis.
Xu X, Shu C, Wu X, Ouyang Y, Cheng H, Zhou Y, Wang H, He C, Xie C, He X, Hong J, Lu N, Ge Z, Zhu Y, Li N
Frontiers in microbiology 2022;13:1065462
Frontiers in microbiology 2022;13:1065462
Corilagin alleviates intestinal ischemia/reperfusion-induced intestinal and lung injury in mice via inhibiting NLRP3 inflammasome activation and pyroptosis.
Li W, Yang K, Li B, Wang Y, Liu J, Chen D, Diao Y
Frontiers in pharmacology 2022;13:1060104
Frontiers in pharmacology 2022;13:1060104
Vam6 reduces iNKT cell function in tumor via modulating AMPK/mTOR pathways.
Bai S, Wu Q, Zhu S, Zhang Y, Chen X, Su M, Pan J, Li S, Yue T, Xu L, Xie D, Tian C, Zhao D, Li X, Hou J, Wang L, Fu S, Xue Y, Jiang A, Li D, Xu T, Tian Z, Zhou R, Zhang H, Bai L
Frontiers in immunology 2022;13:1051045
Frontiers in immunology 2022;13:1051045
Systematic pan-cancer analysis identifies RALA as a tumor targeting immune therapeutic and prognostic marker.
Jin H, Qin S, He J, Xiao J, Li Q, Mao Y, Zhao L
Frontiers in immunology 2022;13:1046044
Frontiers in immunology 2022;13:1046044
P53 maintains gallid alpha herpesvirus 1 replication by direct regulation of nucleotide metabolism and ATP synthesis through its target genes.
Xu L, Chen Z, Zhang Y, Cui L, Liu Z, Li X, Liu S, Li H
Frontiers in microbiology 2022;13:1044141
Frontiers in microbiology 2022;13:1044141
Oxaloacetate acid ameliorates paraquat-induced acute lung injury by alleviating oxidative stress and mitochondrial dysfunction.
Li W, Li M, Chen K, Tang Y, Yin R, Lan L, Hong G
Frontiers in pharmacology 2022;13:1029775
Frontiers in pharmacology 2022;13:1029775
Berberine prevents lethal EV71 neurological infection in newborn mice.
Cui G, Wang H, Yang C, Zhou X, Wang J, Wang T, Ma T
Frontiers in pharmacology 2022;13:1027566
Frontiers in pharmacology 2022;13:1027566
Matrine, a potential c-Myc inhibitor, suppresses ribosome biogenesis and nucleotide metabolism in myeloid leukemia.
Zhong WJ, Ma L, Yang F, Cao J, Tan J, Li B
Frontiers in pharmacology 2022;13:1027441
Frontiers in pharmacology 2022;13:1027441
Acute hypoxia induced dysregulation of clock-controlled ovary functions.
Ding M, Lu Y, Huang X, Xing C, Hou S, Wang D, Zhang Y, Wang W, Zhang C, Zhang M, Meng F, Liu K, Liu G, Zhao J, Song L
Frontiers in physiology 2022;13:1024038
Frontiers in physiology 2022;13:1024038
Shuangyu Tiaozhi decoction alleviates non-alcoholic fatty liver disease by improving lipid deposition, insulin resistance, and inflammation in vitro and in vivo.
Yin G, Liang H, Sun W, Zhang S, Feng Y, Liang P, Chen S, Liu X, Pan W, Zhang F
Frontiers in pharmacology 2022;13:1016745
Frontiers in pharmacology 2022;13:1016745
Network pharmacology-based and experimental identification of the effects of Renshen Yangrong decoction on myocardial infarction.
Zhao J, Xu X, Yang X
Frontiers in pharmacology 2022;13:1010036
Frontiers in pharmacology 2022;13:1010036
Effect of transferrin glycation induced by high glucose on HK-2 cells in vitro.
Ma Y, Zhou Q, Zhao P, Lv X, Gong C, Gao J, Liu J
Frontiers in endocrinology 2022;13:1009507
Frontiers in endocrinology 2022;13:1009507
Salvianolic acid A regulates pyroptosis of endothelial cells via directly targeting PKM2 and ameliorates diabetic atherosclerosis.
Zhu J, Chen H, Le Y, Guo J, Liu Z, Dou X, Lu D
Frontiers in pharmacology 2022;13:1009229
Frontiers in pharmacology 2022;13:1009229
Optimized mobilization of MHC class I- and II- restricted immunity by dendritic cell vaccine potentiates cancer therapy.
Shi Y, Liu Y, Huang J, Luo Z, Guo X, Jiang M, Li X, Lu Y, Liu X, Shan X, Luo L, You J
Theranostics 2022;12(7):3488-3502
Theranostics 2022;12(7):3488-3502
Non-invasive photobiomodulation treatment in an Alzheimer Disease-like transgenic rat model.
Yang L, Wu C, Parker E, Li Y, Dong Y, Tucker L, Brann DW, Lin HW, Zhang Q
Theranostics 2022;12(5):2205-2231
Theranostics 2022;12(5):2205-2231
Lgr5 (+) cell fate regulation by coordination of metabolic nuclear receptors during liver repair.
Qin D, Liu S, Lu Y, Yan Y, Zhang J, Cao S, Chen M, Chen N, Huang W, Wang L, Chen X, Zhang L
Theranostics 2022;12(14):6130-6142
Theranostics 2022;12(14):6130-6142
Continuous theta-burst stimulation enhances and sustains neurogenesis following ischemic stroke.
Zong X, Gu J, Zhou S, Ding D, Hu Y, Tucker L, Huang Z, Geng D, Gao D
Theranostics 2022;12(13):5710-5726
Theranostics 2022;12(13):5710-5726
POLD2 is activated by E2F1 to promote triple-negative breast cancer proliferation.
Zhang Z
Frontiers in oncology 2022;12:981329
Frontiers in oncology 2022;12:981329
Novel LncRNA ZFHX4-AS1 as a Potential Prognostic Biomarker That Affects the Immune Microenvironment in Ovarian Cancer.
Wang X, Wang Y, Sun F, Xu Y, Zhang Z, Yang C, Zhang L, Lou G
Frontiers in oncology 2022;12:945518
Frontiers in oncology 2022;12:945518
GPR12 Inhibits Apoptosis in Epithelial Ovarian Cancer via the Activation of ERK1/2 Signaling.
Wang L, Yang D, Zhang Y, Jiao Y
Frontiers in oncology 2022;12:932689
Frontiers in oncology 2022;12:932689
Reduction of H3K27cr Modification During DNA Damage in Colon Cancer.
Liao M, Chu W, Sun X, Zheng W, Gao S, Li D, Pei D
Frontiers in oncology 2022;12:924061
Frontiers in oncology 2022;12:924061
Isolation, characterization, and functional study of extracellular vesicles derived from Leishmania tarentolae.
Shokouhy M, Sarvnaz H, Taslimi Y, Lajevardi MS, Habibzadeh S, Mizbani A, Shekari F, Behbahani M, Torrecilhas AC, Rafati S
Frontiers in cellular and infection microbiology 2022;12:921410
Frontiers in cellular and infection microbiology 2022;12:921410
Glia Maturation Factor β as a Novel Independent Prognostic Biomarker and Potential Therapeutic Target of Kidney Renal Clear Cell Carcinoma.
Zhu T, Wang T, Feng Z, Gao F, Zhang J, Jin C, Tian H, Xu J, Chen H, Ou Q, Wang J, Xu G, Lu L
Frontiers in oncology 2022;12:880100
Frontiers in oncology 2022;12:880100
Nrf2 Overexpression Decreases Vincristine Chemotherapy Sensitivity Through the PI3K-AKT Pathway in Adult B-Cell Acute Lymphoblastic Leukemia.
Wang L, Liu X, Kang Q, Pan C, Zhang T, Feng C, Chen L, Wei S, Wang J
Frontiers in oncology 2022;12:876556
Frontiers in oncology 2022;12:876556
OCT4 induces EMT and promotes ovarian cancer progression by regulating the PI3K/AKT/mTOR pathway.
Xie W, Yu J, Yin Y, Zhang X, Zheng X, Wang X
Frontiers in oncology 2022;12:876257
Frontiers in oncology 2022;12:876257
Integrated Network Pharmacology and Experimental Verification to Explore the Molecular Mechanism of Hedysarum Multijugum Maxim-Curcumae Rhizoma Herb Pair for Treating Non-Small Cell Lung Cancer.
Hu S, Ge M, Zhang S, Jiang M, Hu K, Gao L
Frontiers in oncology 2022;12:854596
Frontiers in oncology 2022;12:854596
The hnRNPK/A1/R/U Complex Regulates Gene Transcription and Translation and is a Favorable Prognostic Biomarker for Human Colorectal Adenocarcinoma.
Li Y, Wang H, Wan J, Ma Q, Qi Y, Gu Z
Frontiers in oncology 2022;12:845931
Frontiers in oncology 2022;12:845931
The Long Non-Coding RNA HOXC-AS3 Promotes Glioma Progression by Sponging miR-216 to Regulate F11R Expression.
Li Y, Peng L, Cao X, Yang K, Wang Z, Xiao Y, Xiao H, Qian C, Liu H
Frontiers in oncology 2022;12:845009
Frontiers in oncology 2022;12:845009
CD147 Mediates 5-Fluorouracil Resistance in Colorectal Cancer by Reprogramming Glycolipid Metabolism.
Dong S, Li S, Wang X, Liang S, Zhang W, Li L, Xu Q, Shi B, Cheng Z, Zhang X, Zhong M, Zhang G, Hu S
Frontiers in oncology 2022;12:813852
Frontiers in oncology 2022;12:813852
Neutrophils Promote Tumor Progression in Oral Squamous Cell Carcinoma by Regulating EMT and JAK2/STAT3 Signaling Through Chemerin.
Hu X, Xiang F, Feng Y, Gao F, Ge S, Wang C, Zhang X, Wang N
Frontiers in oncology 2022;12:812044
Frontiers in oncology 2022;12:812044
Ciclopirox Olamine Exerts Tumor-Suppressor Effects via Topoisomerase II Alpha in Lung Adenocarcinoma.
Yin J, Che G, Jiang K, Zhou Z, Wu L, Xu M, Liu J, Yan S
Frontiers in oncology 2022;12:791916
Frontiers in oncology 2022;12:791916
The oral microbiome in young women at different stages of periodontitis: Prevotella dominant in stage III periodontitis.
Zhao Y, Feng Y, Ye Q, Hu J, Feng Y, Ouyang Z, Zhao J, Chen Y, Tan L, Chen N, Dusenge MA, Su X, Guo Y
Frontiers in cellular and infection microbiology 2022;12:1047607
Frontiers in cellular and infection microbiology 2022;12:1047607
Dual-fluorescent reporter for live-cell imaging of the ER during DENV infection.
Corliss L, Holliday M, Lennemann NJ
Frontiers in cellular and infection microbiology 2022;12:1042735
Frontiers in cellular and infection microbiology 2022;12:1042735
Genome-wide association studies identify miRNA-194 as a prognostic biomarker for gastrointestinal cancer by targeting ATP6V1F, PPP1R14B, BTF3L4 and SLC7A5.
Huang P, Xia L, Guo Q, Huang C, Wang Z, Huang Y, Qin S, Leng W, Li D
Frontiers in oncology 2022;12:1025594
Frontiers in oncology 2022;12:1025594
Consistent downregulation of the cleft lip/palate-associated genes IRF6 and GRHL3 in carcinomas.
Parisi L, Mockenhaupt C, Rihs S, Mansour F, Katsaros C, Degen M
Frontiers in oncology 2022;12:1023072
Frontiers in oncology 2022;12:1023072
Reversion of methionine addiction of osteosarcoma cells to methionine independence results in loss of malignancy, modulation of the epithelial-mesenchymal phenotype and alteration of histone-H3 lysine-methylation.
Aoki Y, Han Q, Tome Y, Yamamoto J, Kubota Y, Masaki N, Obara K, Hamada K, Wang JD, Inubushi S, Bouvet M, Clarke SG, Nishida K, Hoffman RM
Frontiers in oncology 2022;12:1009548
Frontiers in oncology 2022;12:1009548
Cinnamic Acid Improved Lipopolysaccharide-Induced Depressive-Like Behaviors by Inhibiting Neuroinflammation and Oxidative Stress in Mice.
Zhuo R, Cheng X, Luo L, Yang L, Zhao Y, Zhou Y, Peng L, Jin X, Cui L, Liu F, Yang L
Pharmacology 2022;107(5-6):281-289
Pharmacology 2022;107(5-6):281-289
PIN1 protects auditory hair cells from senescence via autophagy.
Lv Z, Zhang Y, Cao H, Liu Q, Feng X, Yin H, Wang B
PeerJ 2022;10:e14267
PeerJ 2022;10:e14267
Overexpression of LINC00551 promotes autophagy-dependent ferroptosis of lung adenocarcinoma via upregulating DDIT4 by sponging miR-4328.
Peng X, Yang R, Peng W, Zhao Z, Tu G, He B, Cai Q, Shi S, Yin W, Yu F, Tao Y, Wang X
PeerJ 2022;10:e14180
PeerJ 2022;10:e14180
G3BP2, a stress granule assembly factor, is dispensable for spermatogenesis in mice.
Yun D, Zhou L, Shi J, Li X, Wu X, Sun F
PeerJ 2022;10:e13532
PeerJ 2022;10:e13532
Ferulic acid attenuates high glucose-induced apoptosis in retinal pigment epithelium cells and protects retina in db/db mice.
Zhu D, Zou W, Cao X, Xu W, Lu Z, Zhu Y, Hu X, Hu J, Zhu Q
PeerJ 2022;10:e13375
PeerJ 2022;10:e13375
Icaritin attenuates 6-OHDA-induced MN9D cell damage by inhibiting oxidative stress.
Zhou X, Huang N, Hou X, Zhu L, Xie Y, Ba Z, Luo Y
PeerJ 2022;10:e13256
PeerJ 2022;10:e13256
Dexamethasone Alleviates Myocardial Injury in a Rat Model of Acute Myocardial Infarction Supported by Venoarterial Extracorporeal Membrane Oxygenation.
Cheng X, Zhang R, Wei S, Huang J, Zhai K, Li Y, Gao B
Frontiers in public health 2022;10:900751
Frontiers in public health 2022;10:900751
CircFGGY Inhibits Cell Growth, Invasion and Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma via Regulating the miR-545-3p/Smad7 Axis.
Feng KL, Diao N, Zhou ZW, Fang CK, Wang JN, Zhang Y, Luo R, Zhong C
Frontiers in cell and developmental biology 2022;10:850708
Frontiers in cell and developmental biology 2022;10:850708
Poloxamer 407 and Hyaluronic Acid Thermosensitive Hydrogel-Encapsulated Ginsenoside Rg3 to Promote Skin Wound Healing.
Peng X, Ding C, Zhao Y, Hao M, Liu W, Yang M, Xiao F, Zheng Y
Frontiers in bioengineering and biotechnology 2022;10:831007
Frontiers in bioengineering and biotechnology 2022;10:831007
Mechanical Stimulation Protects Against Chondrocyte Pyroptosis Through Irisin-Induced Suppression of PI3K/Akt/NF-κB Signal Pathway in Osteoarthritis.
Jia S, Yang Y, Bai Y, Wei Y, Zhang H, Tian Y, Liu J, Bai L
Frontiers in cell and developmental biology 2022;10:797855
Frontiers in cell and developmental biology 2022;10:797855
Effect of condylar chondrocyte exosomes on condylar cartilage osteogenesis in rats under tensile stress.
Shi Y, Shao J, Zhang Z, Zhang J, Lu H
Frontiers in bioengineering and biotechnology 2022;10:1061855
Frontiers in bioengineering and biotechnology 2022;10:1061855
The single-atom iron nanozyme mimicking peroxidase remodels energy metabolism and tumor immune landscape for synergistic chemodynamic therapy and photothermal therapy of triple-negative breast cancer.
Qian X, Shi R, Chen J, Wang Y, Han X, Sun Y, Ling C, Wang G, Xu AW, Pan Y
Frontiers in bioengineering and biotechnology 2022;10:1026761
Frontiers in bioengineering and biotechnology 2022;10:1026761
Influenza virus NS1 interacts with 14-3-3ε to antagonize the production of RIG-I-mediated type I interferons.
Wang T, Wei F, Jiang Z, Song J, Li C, Liu J
Virology 2022 Sep;574:47-56
Virology 2022 Sep;574:47-56
Calycosin suppresses colorectal cancer progression by targeting ERβ, upregulating PTEN, and inhibiting PI3K/Akt signal pathway.
Zhu L, Liu S, Liao YF, Sheng YM, He JC, Cai ZX, Man Q, Wu YY
Cell biology international 2022 Sep;46(9):1367-1377
Cell biology international 2022 Sep;46(9):1367-1377
Ginsenoside Rg3 increases gemcitabine sensitivity of pancreatic adenocarcinoma via reducing ZFP91 mediated TSPYL2 destabilization.
Pan H, Yang L, Bai H, Luo J, Deng Y
Journal of ginseng research 2022 Sep;46(5):636-645
Journal of ginseng research 2022 Sep;46(5):636-645
Puerarin-V prevents the progression of hypoxia- and monocrotaline-induced pulmonary hypertension in rodent models.
Chen D, Zhang HF, Yuan TY, Sun SC, Wang RR, Wang SB, Fang LH, Lyu Y, Du GH
Acta pharmacologica Sinica 2022 Sep;43(9):2325-2339
Acta pharmacologica Sinica 2022 Sep;43(9):2325-2339
Analgesic effect of nobiletin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
Zhu C, Tian M, Liu N, Ma L, Lan X, Yang J, Du J, Ma H, Li Y, Zheng P, Yu J, Peng X
Phytotherapy research : PTR 2022 Sep;36(9):3644-3661
Phytotherapy research : PTR 2022 Sep;36(9):3644-3661
Interleukin 32 participates in cardiomyocyte-induced oxidative stress, inflammation and apoptosis during hypoxia/reoxygenation via the NOD2/NOX2/MAPK signaling pathway.
Li Y, Wang Z
Experimental and therapeutic medicine 2022 Sep;24(3):567
Experimental and therapeutic medicine 2022 Sep;24(3):567
Grifola frondosa Polysaccharide Ameliorates Early Diabetic Nephropathy by Suppressing the TLR4/NF-κB Pathway.
Jiang T, Shen S, Wang L, Zhao M, Li Y, Huang S
Applied biochemistry and biotechnology 2022 Sep;194(9):4093-4104
Applied biochemistry and biotechnology 2022 Sep;194(9):4093-4104
Hydrogen gas promotes apoptosis of lung adenocarcinoma A549 cells through X-linked inhibitor of apoptosis and baculoviral inhibitor of apoptosis protein repeat-containing 3.
Zhang Y, Chen G, Yan Z, Wang L, Wang D
Journal of cancer research and therapeutics 2022 Sep;18(5):1380-1386
Journal of cancer research and therapeutics 2022 Sep;18(5):1380-1386
Substitution of SERCA2 Cys(674) accelerates aortic aneurysm by inducing endoplasmic reticulum stress and promoting cell apoptosis.
Wang L, Yang Z, Wang S, Que Y, Shu X, Wu F, Liu G, Li S, Hu P, Chen H, Shi J, Tong X
British journal of pharmacology 2022 Sep;179(17):4423-4439
British journal of pharmacology 2022 Sep;179(17):4423-4439
Tubuloside B, isolated from Cistanche tubulosa, a promising agent against M1 macrophage activation via synergistically targeting Mob1 and ERK1/2.
Xiao L, Yao J, Miao Y, Ou B, Wang J, Huang Y, Zhou B, Ge L, Tian J, Zeng X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113414
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113414
LARP6 Regulates Keloid Fibroblast Proliferation, Invasion, and Ability to Synthesize Collagen.
Chen L, Su Y, Yin B, Li S, Cheng X, He Y, Jia C
The Journal of investigative dermatology 2022 Sep;142(9):2395-2405.e7
The Journal of investigative dermatology 2022 Sep;142(9):2395-2405.e7
Anti-inflammatory effect of Bifidobacterium animalis subsp. lactis A6 on DSS-induced colitis in mice.
Wang H, Fan C, Zhao Z, Zhai Z, Hao Y
Journal of applied microbiology 2022 Sep;133(3):2063-2073
Journal of applied microbiology 2022 Sep;133(3):2063-2073
MiR-1306-5p promotes cell proliferation and inhibits cell apoptosis in acute myeloid leukemia by downregulating PHF6 expression.
Gao X, Fan S, Zhang X
Leukemia research 2022 Sep;120:106906
Leukemia research 2022 Sep;120:106906
Magnoflorine attenuates inflammatory responses in RA by regulating the PI3K/Akt/NF-κB and Keap1-Nrf2/HO-1 signalling pathways in vivo and in vitro.
Shen Y, Fan X, Qu Y, Tang M, Huang Y, Peng Y, Fu Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154339
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154339
BRD7 restrains TNF-α-induced proliferation and migration of airway smooth muscle cells by inhibiting notch signaling.
Li H, Yang T, Chen T, Liu Y, Pang Y, Yang L
Experimental lung research 2022 Sep-Oct;48(7-8):199-212
Experimental lung research 2022 Sep-Oct;48(7-8):199-212
A deafness-associated mitochondrial DNA mutation caused pleiotropic effects on DNA replication and tRNA metabolism.
Meng F, Jia Z, Zheng J, Ji Y, Wang J, Xiao Y, Fu Y, Wang M, Ling F, Guan MX
Nucleic acids research 2022 Sep 9;50(16):9453-9469
Nucleic acids research 2022 Sep 9;50(16):9453-9469
Proteomic and Biochemical Approaches Elucidate the Role of Millimeter-Wave Irradiation in Wheat Growth under Flooding Stress.
Komatsu S, Tsutsui Y, Furuya T, Yamaguchi H, Hitachi K, Tsuchida K, Tani M
International journal of molecular sciences 2022 Sep 8;23(18)
International journal of molecular sciences 2022 Sep 8;23(18)
Discovery and characterization of heterogeneous and multipotent fibroblast populations isolated from excised cleft lip tissue.
Parisi L, Rihs S, La Scala GC, Schnyder I, Katsaros C, Degen M
Stem cell research & therapy 2022 Sep 8;13(1):469
Stem cell research & therapy 2022 Sep 8;13(1):469
Down-Regulation of Double C2 Domain Alpha Promotes the Formation of Hyperplastic Nerve Fibers in Aganglionic Segments of Hirschsprung's Disease.
Xiao J, Meng X, Chen K, Wang J, Wu L, Chen Y, Yu X, Feng J, Li Z
International journal of molecular sciences 2022 Sep 6;23(18)
International journal of molecular sciences 2022 Sep 6;23(18)
TRIM36 inhibits tumorigenesis through the Wnt/β-catenin pathway and promotes caspase-dependent apoptosis in hepatocellular carcinoma.
Tong Q, Yi M, Kong P, Xu L, Huang W, Niu Y, Gan X, Zhan H, Tian R, Yan D
Cancer cell international 2022 Sep 6;22(1):278
Cancer cell international 2022 Sep 6;22(1):278
LINC00839 promotes colorectal cancer progression by recruiting RUVBL1/Tip60 complexes to activate NRF1.
Liu X, Chen J, Zhang S, Liu X, Long X, Lan J, Zhou M, Zheng L, Zhou J
EMBO reports 2022 Sep 5;23(9):e54128
EMBO reports 2022 Sep 5;23(9):e54128
Zika virus alters centrosome organization to suppress the innate immune response.
Kodani A, Knopp KA, Di Lullo E, Retallack H, Kriegstein AR, DeRisi JL, Reiter JF
EMBO reports 2022 Sep 5;23(9):e52211
EMBO reports 2022 Sep 5;23(9):e52211
A 3D-printed molybdenum-containing scaffold exerts dual pro-osteogenic and anti-osteoclastogenic effects to facilitate alveolar bone repair.
Tian B, Li X, Zhang J, Zhang M, Gan D, Deng D, Sun L, He X, Wu C, Chen F
International journal of oral science 2022 Sep 5;14(1):45
International journal of oral science 2022 Sep 5;14(1):45
Spermidine protects against acute kidney injury by modulating macrophage NLRP3 inflammasome activation and mitochondrial respiration in an eIF5A hypusination-related pathway.
Li X, Zhou X, Liu X, Li X, Jiang X, Shi B, Wang S
Molecular medicine (Cambridge, Mass.) 2022 Sep 4;28(1):103
Molecular medicine (Cambridge, Mass.) 2022 Sep 4;28(1):103
Gasdermin D is involved in switching from apoptosis to pyroptosis in TLR4-mediated renal tubular epithelial cells injury in diabetic kidney disease.
Yuan S, Wang Y, Li Z, Chen X, Song P, Chen A, Qu Z, Wen S, Liu H, Zhu X
Archives of biochemistry and biophysics 2022 Sep 30;727:109347
Archives of biochemistry and biophysics 2022 Sep 30;727:109347
Combinatorial approaches for mitigating resistance to KRAS-targeted therapies.
Warren HR, Ross SJ, Smith PD, Coulson JM, Prior IA
The Biochemical journal 2022 Sep 30;479(18):1985-1997
The Biochemical journal 2022 Sep 30;479(18):1985-1997
Disulfiram alleviates pristane-induced lupus via inhibiting GSDMD-mediated pyroptosis.
Zhuang L, Luo X, Wu S, Lin Z, Zhang Y, Zhai Z, Yang F, Li Y, Zhuang J, Luo G, Xu W, He Y, Sun E
Cell death discovery 2022 Sep 3;8(1):379
Cell death discovery 2022 Sep 3;8(1):379
Morchella esculenta polysaccharide attenuate obesity, inflammation and modulate gut microbiota.
Rehman AU, Khan AI, Xin Y, Liang W
AMB Express 2022 Sep 3;12(1):114
AMB Express 2022 Sep 3;12(1):114
Moxidectin induces autophagy arrest in colorectal cancer.
Mao Y, Xie H, Shu D, Cheng L, Lan J, Pan K
Medical oncology (Northwood, London, England) 2022 Sep 29;39(12):211
Medical oncology (Northwood, London, England) 2022 Sep 29;39(12):211
A New Long Noncoding RNA, MAHAT, Inhibits Replication of Porcine Reproductive and Respiratory Syndrome Virus by Recruiting DDX6 To Bind to ZNF34 and Promote an Innate Immune Response.
Liu Y, Liu X, Bai J, Sun Y, Nauwynck H, Wang X, Yang Y, Jiang P
Journal of virology 2022 Sep 28;96(18):e0115422
Journal of virology 2022 Sep 28;96(18):e0115422
Duck Tembusu Virus Inhibits Type I Interferon Production through the JOSD1-SOCS1-IRF7 Negative-Feedback Regulation Pathway.
Huang S, Huang J, Cui M, Wu X, Wang M, Zhu D, Chen S, Liu M, Zhao X, Wu Y, Yang Q, Zhang S, Ou X, Mao S, Gao Q, Yu Y, Tian B, Liu Y, Zhang L, Yin Z, Jing B, Chen X, Cheng A, Jia R
Journal of virology 2022 Sep 28;96(18):e0093022
Journal of virology 2022 Sep 28;96(18):e0093022
Apelin-13 reduces lipopolysaccharide-induced neuroinflammation and cognitive impairment via promoting glucocorticoid receptor expression and nuclear translocation.
Hu S, Shen P, Chen B, Tian SW, You Y
Neuroscience letters 2022 Sep 25;788:136850
Neuroscience letters 2022 Sep 25;788:136850
Downregulation of miR-30b-5p Facilitates Chondrocyte Hypertrophy and Apoptosis via Targeting Runx2 in Steroid-Induced Osteonecrosis of the Femoral Head.
Lin L, Yu Y, Liu K, Jiang Y, Zhou Z
International journal of molecular sciences 2022 Sep 24;23(19)
International journal of molecular sciences 2022 Sep 24;23(19)
A homozygous PIWIL2 frameshift variant affects the formation and maintenance of human-induced pluripotent stem cell-derived spermatogonial stem cells and causes Sertoli cell-only syndrome.
Wang X, Li Z, Qu M, Xiong C, Li H
Stem cell research & therapy 2022 Sep 24;13(1):480
Stem cell research & therapy 2022 Sep 24;13(1):480
Realgar Alleviated Neuroinflammation Induced by High Protein and High Calorie Diet in Rats via the Microbiota-Gut-Brain Axis.
Feng C, Li A, Yin C, Wang S, Jin W, Liu Y, Huo T, Jiang H
Nutrients 2022 Sep 23;14(19)
Nutrients 2022 Sep 23;14(19)
Probing the Potential Mechanism of Quercetin and Kaempferol against Heat Stress-Induced Sertoli Cell Injury: Through Integrating Network Pharmacology and Experimental Validation.
Liu DL, Liu SJ, Hu SQ, Chen YC, Guo J
International journal of molecular sciences 2022 Sep 22;23(19)
International journal of molecular sciences 2022 Sep 22;23(19)
Daidzein alleviates doxorubicin-induced heart failure via the SIRT3/FOXO3a signaling pathway.
Li H, Zhang M, Wang Y, Gong K, Yan T, Wang D, Meng X, Yang X, Chen Y, Han J, Duan Y, Zhang S
Food & function 2022 Sep 22;13(18):9576-9588
Food & function 2022 Sep 22;13(18):9576-9588
Genistein Restricts the Epithelial Mesenchymal Transformation (EMT) and Stemness of Hepatocellular Carcinoma via Upregulating miR-1275 to Inhibit the EIF5A2/PI3K/Akt Pathway.
Yang X, Jiang W, Kong X, Zhou X, Zhu D, Kong L
Biology 2022 Sep 22;11(10)
Biology 2022 Sep 22;11(10)
Inhibition of cannabinoid receptor type 1 sensitizes triple-negative breast cancer cells to ferroptosis via regulating fatty acid metabolism.
Li P, Lin Q, Sun S, Yang N, Xia Y, Cao S, Zhang W, Li Q, Guo H, Zhu M, Wang Y, Zheng Z, Li S
Cell death & disease 2022 Sep 21;13(9):808
Cell death & disease 2022 Sep 21;13(9):808
Colletofragarone A2 Inhibits Cancer Cell Growth In Vivo and Leads to the Degradation and Aggregation of Mutant p53.
Sadahiro Y, Hitora Y, Kimura I, Hitora-Imamura N, Onodera R, Motoyama K, Tsukamoto S
Chemical research in toxicology 2022 Sep 19;35(9):1598-1603
Chemical research in toxicology 2022 Sep 19;35(9):1598-1603
Effect of crude polysaccharide from seaweed, Dictyopteris divaricata (CDDP) on gut microbiota restoration and anti-diabetic activity in streptozotocin (STZ)-induced T1DM mice.
Siddiqui NZ, Rehman AU, Yousuf W, Khan AI, Farooqui NA, Zang S, Xin Y, Wang L
Gut pathogens 2022 Sep 17;14(1):39
Gut pathogens 2022 Sep 17;14(1):39
Curcumin regulates anti-inflammatory responses by AXL/JAK2/STAT3 signaling pathway in experimental autoimmune encephalomyelitis.
Sun M, Liu N, Sun J, Li X, Wang H, Zhang W, Xie Q, Wang M
Neuroscience letters 2022 Sep 14;787:136821
Neuroscience letters 2022 Sep 14;787:136821
Endothelial cells regulated by RNF20 orchestrate the proliferation and differentiation of neural precursor cells during embryonic development.
Zhang M, Su L, Wang W, Li C, Liang Q, Ji F, Jiao J
Cell reports 2022 Sep 13;40(11):111350
Cell reports 2022 Sep 13;40(11):111350
Senescent Phenotype of Astrocytes Leads to Activation of BV2 Microglia and N2a Neuronal Cells Death.
Zhang W, Yang X, Liu J, Pan Y, Zhang M, Chen L
Molecules (Basel, Switzerland) 2022 Sep 12;27(18)
Molecules (Basel, Switzerland) 2022 Sep 12;27(18)
Placental expression of estrogen-related receptor gamma is reduced in fetal growth restriction pregnancies and is mediated by hypoxia†.
Zou Z, Harris LK, Forbes K, Heazell AEP
Biology of reproduction 2022 Sep 12;107(3):846-857
Biology of reproduction 2022 Sep 12;107(3):846-857
Glycogen metabolism reprogramming promotes inflammation in coal dust-exposed lung.
Wang W, Mu M, Zou Y, Deng S, Lu Y, Li Q, Li Z, Tao H, Wang Y, Tao X
Ecotoxicology and environmental safety 2022 Sep 1;242:113913
Ecotoxicology and environmental safety 2022 Sep 1;242:113913
Phellinus linteus polysaccharides mediates acetaminophen-induced hepatotoxicity via activating AMPK/Nrf2 signaling pathways.
Zhao L, Zheng L, Li Z, Jin M, Wang Q, Cheng J, Li J, Feng H
Aging 2022 Sep 1;14(17):6993-7002
Aging 2022 Sep 1;14(17):6993-7002
FTO-dependent N(6)-Methyladenosine regulates the progression of endometriosis via the ATG5/PKM2 Axis.
Wang H, Liang Z, Gou Y, Li Z, Cao Y, Jiao N, Tan J, Yu Y, Zhang Z
Cellular signalling 2022 Oct;98:110406
Cellular signalling 2022 Oct;98:110406
New Deferric Amine Compounds Efficiently Chelate Excess Iron to Treat Iron Overload Disorders and to Prevent Ferroptosis.
Feng W, Xiao Y, Zhao C, Zhang Z, Liu W, Ma J, Ganz T, Zhang J, Liu S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Oct;9(29):e2202679
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Oct;9(29):e2202679
Palmitoylation of MDH2 by ZDHHC18 activates mitochondrial respiration and accelerates ovarian cancer growth.
Pei X, Li KY, Shen Y, Li JT, Lei MZ, Fang CY, Lu HJ, Yang HJ, Wen W, Yin M, Qu J, Lei QY
Science China. Life sciences 2022 Oct;65(10):2017-2030
Science China. Life sciences 2022 Oct;65(10):2017-2030
High expression of eIF4A1 predicts unfavorable prognosis in clear cell renal cell carcinoma.
Zhang LL, Chang W, He SB, Zhang B, Ma G, Shang PF, Yue ZJ
Molecular and cellular probes 2022 Oct;65:101845
Molecular and cellular probes 2022 Oct;65:101845
Glibenclamide Directly Prevents Neuroinflammation by Targeting SUR1-TRPM4-Mediated NLRP3 Inflammasome Activation In Microglia.
He Y, Chang Y, Peng Y, Zhu J, Liu K, Chen J, Wu Y, Ji Z, Lin Z, Wang S, Gupta S, Zang N, Pan S, Huang K
Molecular neurobiology 2022 Oct;59(10):6590-6607
Molecular neurobiology 2022 Oct;59(10):6590-6607
HDAC6 Inhibition Alleviates Anesthesia and Surgery-Induced Less Medial Prefrontal-Dorsal Hippocampus Connectivity and Cognitive Impairment in Aged Rats.
Chen J, Liu S, Wang X, Huang J, Phillips J, Ma D, Ouyang W, Tong J
Molecular neurobiology 2022 Oct;59(10):6158-6169
Molecular neurobiology 2022 Oct;59(10):6158-6169
High expression of Sam68 contributes to metastasis by regulating vimentin expression and a motile phenotype in oral squamous cell carcinoma.
Komiyama T, Kuroshima T, Sugasawa T, Fujita SI, Ikami Y, Hirai H, Tsushima F, Michi Y, Kayamori K, Higashino F, Harada H
Oncology reports 2022 Oct;48(4)
Oncology reports 2022 Oct;48(4)
Exogenous TIPE2 Inhibit TAK1 to Improve Inflammation and Neuropathic Pain Induced by Sciatic Nerve Injury Through Inactivating NF-κB and JNK.
Sun X, Li X, Zhou Y, Wang Y, Liu X
Neurochemical research 2022 Oct;47(10):3167-3177
Neurochemical research 2022 Oct;47(10):3167-3177
Yajieshaba prevents lipopolysaccharide-induced intestinal barrier injuryanti-inflammatory and anti-apoptosis.
Liping Y, Xinglin YU, Chao Z, Pu C, Xiaohua D
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Oct;42(5):707-714
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Oct;42(5):707-714
Identification of Trovafloxacin, Ozanimod, and Ozenoxacin as Potent c-Myc G-Quadruplex Stabilizers to Suppress c-Myc Transcription and Myeloma Growth.
Zhang J, Wang T, Geng X, Liu L, Gao J
Molecular informatics 2022 Oct;41(10):e2200011
Molecular informatics 2022 Oct;41(10):e2200011
CDGSH iron sulfur domain 2 mitigates apoptosis, oxidative stress and inflammatory response caused by oxygen-glucose deprivation/reoxygenation in HT22 hippocampal neurons by Akt-Nrf2-activated pathway.
Ren X, Yu J, Guo L, Zhang Z
Metabolic brain disease 2022 Oct;37(7):2417-2429
Metabolic brain disease 2022 Oct;37(7):2417-2429
Pirh2 restricts influenza A virus replication by modulating short-chain ubiquitination of its nucleoprotein.
Chen H, Gao X, Zhao S, Bao C, Ming X, Qian Y, Zhou Y, Jung YS
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Oct;36(10):e22537
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Oct;36(10):e22537
A single-beam of light priming the immune responses and boosting cancer photoimmunotherapy.
Sun Y, Han R, Wang J, Qin Y, Ren Z, Feng X, Liu Q, Wang X
Journal of controlled release : official journal of the Controlled Release Society 2022 Oct;350:734-747
Journal of controlled release : official journal of the Controlled Release Society 2022 Oct;350:734-747
Organophosphate flame retardant TDCPP: A risk factor for renal cancer?
Zhou X, Zhou X, Yao L, Zhang X, Cong R, Luan J, Zhang T, Song N
Chemosphere 2022 Oct;305:135485
Chemosphere 2022 Oct;305:135485
Upregulation of Wilms' Tumor 1 in epicardial cells increases cardiac fibrosis in dystrophic mice.
Guo Z, Geng M, Huang Y, Han G, Jing R, Lin C, Zhang X, Zhang M, Fan G, Wang F, Yin H
Cell death and differentiation 2022 Oct;29(10):1928-1940
Cell death and differentiation 2022 Oct;29(10):1928-1940
Effects of intraperitoneal injection of lipopolysaccharide-induced peripheral inflammation on dopamine neuron damage in rat midbrain.
Yang QY, Li XW, Yang R, Qin TY, Long H, Zhang SB, Zhang F
CNS neuroscience & therapeutics 2022 Oct;28(10):1624-1636
CNS neuroscience & therapeutics 2022 Oct;28(10):1624-1636
SNORA70E promotes the occurrence and development of ovarian cancer through pseudouridylation modification of RAP1B and alternative splicing of PARPBP.
Chen S, Li QH, Chen X, Bao HJ, Wu W, Shen F, Lu BF, Jiang RQ, Zong ZH, Zhao Y
Journal of cellular and molecular medicine 2022 Oct;26(20):5150-5164
Journal of cellular and molecular medicine 2022 Oct;26(20):5150-5164
IMP075 targeting ClpP for colon cancer therapy in vivo and in vitro.
Zhang J, Luo B, Sui J, Qiu Z, Huang J, Yang T, Luo Y
Biochemical pharmacology 2022 Oct;204:115232
Biochemical pharmacology 2022 Oct;204:115232
Angiotensin II type-2 receptor activation in alveolar macrophages mediates protection against cigarette smoke-induced chronic obstructive pulmonary disease.
Mei D, Liao W, Gan PXL, Tran QTN, Chan CCMY, Heng CKM, Wong WSF
Pharmacological research 2022 Oct;184:106469
Pharmacological research 2022 Oct;184:106469
Substitution of the SERCA2 Cys(674) reactive thiol accelerates atherosclerosis by inducing endoplasmic reticulum stress and inflammation.
Su H, Mei Y, Luo S, Wu H, He Y, Shiraishi Y, Hu P, Cohen RA, Tong X
British journal of pharmacology 2022 Oct;179(20):4778-4791
British journal of pharmacology 2022 Oct;179(20):4778-4791
CD137 Signal Mediates Cardiac Ischemia-Reperfusion Injury by Regulating the Necrosis of Cardiomyocytes.
Xu Y, Chen R, Yan J, Zang G, Shao C, Wang Z
Journal of cardiovascular translational research 2022 Oct;15(5):1163-1175
Journal of cardiovascular translational research 2022 Oct;15(5):1163-1175
OAS1, OAS2, and OAS3 Contribute to Epidermal Keratinocyte Proliferation by Regulating Cell Cycle and Augmenting IFN-1‒Induced Jak1‒Signal Transducer and Activator of Transcription 1 Phosphorylation in Psoriasis.
Huang YZ, Zheng YX, Zhou Y, Xu F, Cui YZ, Chen XY, Wang ZY, Yan BX, Zheng M, Man XY
The Journal of investigative dermatology 2022 Oct;142(10):2635-2645.e9
The Journal of investigative dermatology 2022 Oct;142(10):2635-2645.e9
Prenatal hypothyroidism diminished exogenous NO-mediated diastolic effects in fetal rat thoracic aorta smooth muscle via increased oxidative stress.
Guo J, Yu X, Liu Y, Lu L, Zhu D, Zhang Y, Li L, Zhang P, Gao Q, Lu X, Sun M
Reproductive toxicology (Elmsford, N.Y.) 2022 Oct;113:52-61
Reproductive toxicology (Elmsford, N.Y.) 2022 Oct;113:52-61
LipoxinA(4) analog BML-111 protects podocytes cultured in high-glucose medium against oxidative injury via activating Nrf2 pathway.
Hao H, Xie F, Xu F, Wang Q, Wu Y, Zhang D
International immunopharmacology 2022 Oct;111:109170
International immunopharmacology 2022 Oct;111:109170
Aucubin promoted neuron functional recovery by suppressing inflammation and neuronal apoptosis in a spinal cord injury model.
Xiao S, Zhong N, Yang Q, Li A, Tong W, Zhang Y, Yao G, Wang S, Liu J, Liu Z
International immunopharmacology 2022 Oct;111:109163
International immunopharmacology 2022 Oct;111:109163
Tumor-associated macrophages promote migration and invasion via modulating IL-6/STAT3 signaling in renal cell carcinoma.
Chen S, Qian S, Zhang L, Pan X, Qu F, Yu Y, Gu Z, Cui X, Shen H
International immunopharmacology 2022 Oct;111:109139
International immunopharmacology 2022 Oct;111:109139
Chicoric acid attenuates tumor necrosis factor-α-induced inflammation and apoptosis via the Nrf2/HO-1, PI3K/AKT and NF-κB signaling pathways in C28/I2 cells and ameliorates the progression of osteoarthritis in a rat model.
Qu Y, Shen Y, Teng L, Huang Y, Yang Y, Jian X, Fan S, Wu P, Fu Q
International immunopharmacology 2022 Oct;111:109129
International immunopharmacology 2022 Oct;111:109129
The role of AMPK-Sirt1-autophagy pathway in the intestinal protection process by propofol against regional ischemia/reperfusion injury in rats.
Liu X, Yang B, Tan YF, Feng JG, Jia J, Yang CJ, Chen Y, Wang MH, Zhou J
International immunopharmacology 2022 Oct;111:109114
International immunopharmacology 2022 Oct;111:109114
Parthenolide modulates cerebral ischemia-induced microglial polarization and alleviates neuroinflammatory injury via the RhoA/ROCK pathway.
Zhang Y, Miao L, Peng Q, Fan X, Song W, Yang B, Zhang P, Liu G, Liu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Oct;105:154373
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Oct;105:154373
Involvement of Rab11 in osteoblastic differentiation: Its up-regulation during the differentiation and by tensile stress.
Thant L, Kakihara Y, Kaku M, Kitami M, Kitami K, Mizukoshi M, Maeda T, Saito I, Saeki M
Biochemical and biophysical research communications 2022 Oct 8;624:16-22
Biochemical and biophysical research communications 2022 Oct 8;624:16-22
Tension of plus-end tracking protein Clip170 confers directionality and aggressiveness during breast cancer migration.
Hu Y, Xie Q, Wu X, Liu W, Li D, Li C, Zhao W, Chen L, Zheng Z, Li G, Guo J
Cell death & disease 2022 Oct 8;13(10):856
Cell death & disease 2022 Oct 8;13(10):856
Relationship between the expression of ARHGAP25 and RhoA in non-small cell lung cancer and vasculogenic mimicry.
Shi F, Wu J, Jia Q, Li K, Li W, Shi Y, Wang Y, Wu S
BMC pulmonary medicine 2022 Oct 7;22(1):377
BMC pulmonary medicine 2022 Oct 7;22(1):377
Bisdemethoxycurcumin Alleviates Dextran Sodium Sulfate-Induced Colitis via Inhibiting NLRP3 Inflammasome Activation and Modulating the Gut Microbiota in Mice.
Zhang J, Li Q, Zhang X, Chen Y, Lu Y, Wang X, Zhang L, Wang T
Antioxidants (Basel, Switzerland) 2022 Oct 7;11(10)
Antioxidants (Basel, Switzerland) 2022 Oct 7;11(10)
NCAPG Promotes Pulmonary Artery Smooth Muscle Cell Proliferation as a Promising Therapeutic Target of Idiopathic Pulmonary Hypertension: Bioinformatics Analysis and Experiment Verification.
Fu B, Li Y, Shi X, Liu P, Zhang Y, Tian H
International journal of molecular sciences 2022 Oct 4;23(19)
International journal of molecular sciences 2022 Oct 4;23(19)
Stratifin as a novel diagnostic biomarker in serum for diffuse alveolar damage.
Arakawa N, Ushiki A, Abe M, Matsuyama S, Saito Y, Kashiwada T, Horimasu Y, Gemma A, Tatsumi K, Hattori N, Tsushima K, Miyashita K, Saito K, Nakamura R, Toyoda T, Ogawa K, Sato M, Takamatsu K, Mori K, Nishiya T, Izumi T, Ohno Y, Saito Y, Hanaoka M
Nature communications 2022 Oct 4;13(1):5854
Nature communications 2022 Oct 4;13(1):5854
Succinate communicates pro-inflammatory signals to the host and regulates bile acid enterohepatic metabolism in a pig model.
Li X, Ren Y, Huang G, Zhang R, Zhang Y, Zhu W, Yu K
Food & function 2022 Oct 31;13(21):11070-11082
Food & function 2022 Oct 31;13(21):11070-11082
Circular RNA circBNC2 inhibits epithelial cell G2-M arrest to prevent fibrotic maladaptive repair.
Wang P, Huang Z, Peng Y, Li H, Lin T, Zhao Y, Hu Z, Zhou Z, Zhou W, Liu Y, Hou FF
Nature communications 2022 Oct 31;13(1):6502
Nature communications 2022 Oct 31;13(1):6502
RNA-seq transcriptome profiling of liver regeneration in mice identifies the miR-34b-5p/phosphoinositide-dependent protein kinase 1 axis as a potential target for hepatocyte proliferation.
Lei X, Dai X, Wang Q, Long R, Xiang Z, Li H, Long Z, Zhang C, Zhu Z
Biochemical and biophysical research communications 2022 Oct 30;627:111-121
Biochemical and biophysical research communications 2022 Oct 30;627:111-121
Sinensetin attenuates IL-1β-induced cartilage damage and ameliorates osteoarthritis by regulating SERPINA3.
Liu Z, Liu R, Wang R, Dai J, Chen H, Wang J, Li X
Food & function 2022 Oct 3;13(19):9973-9987
Food & function 2022 Oct 3;13(19):9973-9987
Naringenin activates beige adipocyte browning in high fat diet-fed C57BL/6 mice by shaping the gut microbiota.
Zhang S, Li J, Shi X, Tan X, Si Q
Food & function 2022 Oct 3;13(19):9918-9930
Food & function 2022 Oct 3;13(19):9918-9930
Lipid-lowering activity of metformin-soluble soybean polysaccharide nanoparticles.
He H, Liu M, He R, Zhao W
Food & function 2022 Oct 3;13(19):10265-10274
Food & function 2022 Oct 3;13(19):10265-10274
The Translational Landscape Revealed the Sequential Treatment Containing ATRA plus PI3K/AKT Inhibitors as an Efficient Strategy for AML Therapy.
Wang K, Ou Z, Deng G, Li S, Su J, Xu Y, Zhou R, Hu W, Chen F
Pharmaceutics 2022 Oct 28;14(11)
Pharmaceutics 2022 Oct 28;14(11)
Paclitaxel Induces the Apoptosis of Prostate Cancer Cells via ROS-Mediated HIF-1α Expression.
Zhang Y, Tang Y, Tang X, Wang Y, Zhang Z, Yang H
Molecules (Basel, Switzerland) 2022 Oct 24;27(21)
Molecules (Basel, Switzerland) 2022 Oct 24;27(21)
Cytomegalovirus-specific neutralizing antibodies effectively prevent uncontrolled infection after allogeneic hematopoietic stem cell transplantation.
Wang H, Liu H, Zhou L, Wang D, Wang S, Liu Q, Wu Y, Tu M, Sun Z, Zheng X, Fu B, Wang B, Wei H
iScience 2022 Oct 21;25(10):105065
iScience 2022 Oct 21;25(10):105065
NUPR1 contributes to radiation resistance by maintaining ROS homeostasis via AhR/CYP signal axis in hepatocellular carcinoma.
Zhan Y, Zhang Z, Liu Y, Fang Y, Xie Y, Zheng Y, Li G, Liang L, Ding Y
BMC medicine 2022 Oct 19;20(1):365
BMC medicine 2022 Oct 19;20(1):365
Tumor microenvironment-related gene selenium-binding protein 1 (SELENBP1) is associated with immunotherapy efficacy and survival in colorectal cancer.
Zhu C, Wang S, Du Y, Dai Y, Huai Q, Li X, Du Y, Dai H, Yuan W, Yin S, Wang H
BMC gastroenterology 2022 Oct 17;22(1):437
BMC gastroenterology 2022 Oct 17;22(1):437
Cellular PSMB4 Protein Suppresses Influenza A Virus Replication through Targeting NS1 Protein.
Yang CH, Hsu CF, Lai XQ, Chan YR, Li HC, Lo SY
Viruses 2022 Oct 17;14(10)
Viruses 2022 Oct 17;14(10)
7-Methoxyisoflavone suppresses vascular endothelial inflammation by inhibiting the expression of endothelial adhesion molecules.
Zhu X, Peng J, Yang L, Guo Y, Wang P, Liu K, Zhu J, Deng S, Liang M
European journal of pharmacology 2022 Oct 15;933:175268
European journal of pharmacology 2022 Oct 15;933:175268
Hypoxia-inducible Factor Regulates Ten-eleven Translocated Methylcytosine Dioxygenase 1-c-Myc Binding Involved in Depression-like Behavior in Prenatal Hypoxia Offspring.
Zeng H, Wei B, Liu J, Lu L, Li L, Wang B, Sun M
Neuroscience 2022 Oct 15;502:41-51
Neuroscience 2022 Oct 15;502:41-51
MicroRNA-122a aggravates intestinal ischemia/reperfusion injury by promoting pyroptosis via targeting EGFR-NLRP3 signaling pathway.
Wang F, Gu L, Wang Y, Sun D, Zhao Y, Meng Q, Yin L, Xu L, Lu X, Peng J, Lin Y, Sun P
Life sciences 2022 Oct 15;307:120863
Life sciences 2022 Oct 15;307:120863
Embryonic Deletion of TXNIP in GABAergic Neurons Enhanced Oxidative Stress in PV+ Interneurons in Primary Somatosensory Cortex of Aging Mice: Relevance to Schizophrenia.
Xue T, Wang X, Hu Y, Cheng Y, Li H, Shi Y, Wang L, Yin D, Cui D
Brain sciences 2022 Oct 15;12(10)
Brain sciences 2022 Oct 15;12(10)
Osteoclast-Driven Osteogenesis, Bone Remodeling and Biomaterial Resorption: A New Profile of BMP2-CPC-Induced Alveolar Bone Regeneration.
Shen H, Zhuang Y, Zhang C, Zhang C, Yuan Y, Yu H, Si J, Shen G
International journal of molecular sciences 2022 Oct 13;23(20)
International journal of molecular sciences 2022 Oct 13;23(20)
Immunity of two novel hepatitis C virus polyepitope vaccines.
Feng T, Li M, Zhang L, Li S, Yang Z, Kang L, Guo Y, Kong L, Wang T
Vaccine 2022 Oct 12;40(43):6277-6287
Vaccine 2022 Oct 12;40(43):6277-6287
The Effect of Circumscribed Exposure to the Pan-Aurora Kinase Inhibitor VX-680 on Proliferating Euploid Cells.
Liu X, Shi Q, Choudhry N, Zhang T, Liu H, Zhang S, Zhang J, Yang D
International journal of molecular sciences 2022 Oct 11;23(20)
International journal of molecular sciences 2022 Oct 11;23(20)
Loss of BAF (mSWI/SNF) chromatin-remodeling ATPase Brg1 causes multiple malformations of cortical development in mice.
Jin Y, Gao X, Lu M, Chen G, Yang X, Ren N, Song Y, Hou C, Li J, Liu Q, Gao J
Human molecular genetics 2022 Oct 10;31(20):3504-3520
Human molecular genetics 2022 Oct 10;31(20):3504-3520
Melanoma stem cells promote metastasis via exosomal miR-1268a inactivation of autophagy.
Li X, Liu D, Chen H, Zeng B, Zhao Q, Zhang Y, Chen Y, Wang J, Xing HR
Biological research 2022 Oct 1;55(1):29
Biological research 2022 Oct 1;55(1):29
Geniposide attenuates spermatogenic dysfunction via inhibiting endoplasmic reticulum stress in male mice.
Chi YN, Ye RJ, Yang JM, Hai DM, Liu N, Ren JW, Du J, Lan XB, Yu JQ, Ma L
Chemico-biological interactions 2022 Oct 1;366:110144
Chemico-biological interactions 2022 Oct 1;366:110144
The Role and Mechanism of CREBH Regulating SIRT3 in Metabolic Associated Fatty Liver Disease.
Junli Z, Shuhan W, Yajuan Z, Xiaoling D, Jiahuan L, Keshu X
Life sciences 2022 Oct 1;306:120838
Life sciences 2022 Oct 1;306:120838
Promotion of tumor progression induced by continuous low-dose administration of antineoplastic agent gemcitabine or gemcitabine combined with cisplatin.
Chen Y, Liu H, Zheng Q, Li H, You H, Feng Y, Feng W
Life sciences 2022 Oct 1;306:120826
Life sciences 2022 Oct 1;306:120826
Role of non-neuronal cholinergic system in the early stage response of epithelial-mesenchymal transformation related markers in A549 cells induced by coal particles.
Wu MY, Shi XC, Shan J, Wang R, Wang Y, Li J, Tian DN, Xu HM
Heliyon 2022 Nov;8(11):e11751
Heliyon 2022 Nov;8(11):e11751
RNF2 mediates pulmonary fibroblasts activation and proliferation by regulating mTOR and p16-CDK4-Rb1 signaling pathway.
Pan L, Hu Y, Qian C, Yao Y, Wang S, Shi W, Xu T
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2022 Nov;71(10-11):1283-1303
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2022 Nov;71(10-11):1283-1303
Selenoprotein K contributes to CD36 subcellular trafficking in hepatocytes by accelerating nascent COPII vesicle formation and aggravates hepatic steatosis.
You M, Wu F, Gao M, Chen M, Zeng S, Zhang Y, Zhao W, Li D, Wei L, Ruan XZ, Chen Y
Redox biology 2022 Nov;57:102500
Redox biology 2022 Nov;57:102500
Gomisin A enhances the antitumor effect of paclitaxel by suppressing oxidative stress in ovarian cancer.
Wang T, Liu J, Huang X, Zhang C, Shangguan M, Chen J, Wu S, Chen M, Yang Z, Zhao S
Oncology reports 2022 Nov;48(5)
Oncology reports 2022 Nov;48(5)
Basolateral Amygdala Reactive Microglia May Contribute to Synaptic Impairment and Depressive-Like Behavior in Mice with Bone Cancer Pain.
Jiang L, Hao J, Yang XL, Zhu JX, Wang Y, Huang YL, Sun YE, Mao YT, Ni K, Gu XP, Ma ZL
Neurochemical research 2022 Nov;47(11):3454-3463
Neurochemical research 2022 Nov;47(11):3454-3463
An oleanolic acid derivative, K73-03, inhibits pancreatic cancer cells proliferation in vitro and in vivo via blocking EGFR/Akt pathway.
Zhou Z, Dong Y, Li N, Niu M, Wang S, Zhou Y, Sun Z, Chu P, Tang Z
Cell biology international 2022 Nov;46(11):1801-1813
Cell biology international 2022 Nov;46(11):1801-1813
Acyl-CoA thioesterase 9 promotes tumour growth and metastasis through reprogramming of fatty acid metabolism in hepatocellular carcinoma.
Wang B, Zhang H, Chen YF, Hu LQ, Tian YY, Tong HW, Wang G, Chen C, Yuan P
Liver international : official journal of the International Association for the Study of the Liver 2022 Nov;42(11):2548-2561
Liver international : official journal of the International Association for the Study of the Liver 2022 Nov;42(11):2548-2561
Roles of C/EBP-homologous protein and histone H3 lysine 4 methylation in arsenic-induced mitochondrial apoptosis in hepatocytes.
Liang C, Xie RJ, Wang JL, Zhang YW, Zhang JY, Yang Q, Han B
Toxicology and industrial health 2022 Nov;38(11):745-756
Toxicology and industrial health 2022 Nov;38(11):745-756
OL-FS13 alleviates experimental cerebral ischemia-reperfusion injury.
Liu N, Li Y, Yang Y, Shu L, Liu Y, Wu Y, Sun D, Kang Z, Zhang Y, Ni D, Wei Z, Li S, Yang M, Wang Y, Sun J, Yang X
Experimental neurology 2022 Nov;357:114180
Experimental neurology 2022 Nov;357:114180
S100A8 regulates autophagy-dependent ferroptosis in microglia after experimental subarachnoid hemorrhage.
Tao Q, Qiu X, Li C, Zhou J, Gu L, Zhang L, Pang J, Zhang L, Yin S, Jiang Y, Peng J
Experimental neurology 2022 Nov;357:114171
Experimental neurology 2022 Nov;357:114171
A Novel Mouse Model of Idiopathic Nephrotic Syndrome Induced by Immunization with the Podocyte Protein Crb2.
Hada I, Shimizu A, Takematsu H, Nishibori Y, Kimura T, Fukutomi T, Kudo A, Ito-Nitta N, Kiuchi Z, Patrakka J, Mikami N, Leclerc S, Akimoto Y, Hirayama Y, Mori S, Takano T, Yan K
Journal of the American Society of Nephrology : JASN 2022 Nov;33(11):2008-2025
Journal of the American Society of Nephrology : JASN 2022 Nov;33(11):2008-2025
Channel HCN4 mutation R666Q associated with sporadic arrhythmia decreases channel electrophysiological function and increases protein degradation.
Wang H, Wu T, Huang Z, Huang J, Geng Z, Cui B, Yan Y, Zhang Y, Wang Y
The Journal of biological chemistry 2022 Nov;298(11):102599
The Journal of biological chemistry 2022 Nov;298(11):102599
A critical ETV4/Twist1/Vimentin axis in Ha-RAS-induced aggressive breast cancer.
Liu W, Gajendran B, Sample KM, Wang C, Hu A, Chen B, Li Y, Zacksenhaus E, Ben-David Y
Cancer gene therapy 2022 Nov;29(11):1590-1599
Cancer gene therapy 2022 Nov;29(11):1590-1599
A novel synthetic chalcone derivative, 2,4,6-trimethoxy-4'-nitrochalcone (Ch-19), exerted anti-tumor effects through stimulating ROS accumulation and inducing apoptosis in esophageal cancer cells.
Yang Y, Wu H, Zou X, Chen Y, He R, Jin Y, Zhou B, Ge C, Yang Y
Cell stress & chaperones 2022 Nov;27(6):645-657
Cell stress & chaperones 2022 Nov;27(6):645-657
Phosphorylation-mediated PI3K-Art signalling pathway as a therapeutic mechanism in the hydrogen-induced alleviation of brain injury in septic mice.
Bai Y, Li L, Dong B, Ma W, Chen H, Yu Y
Journal of cellular and molecular medicine 2022 Nov;26(22):5713-5727
Journal of cellular and molecular medicine 2022 Nov;26(22):5713-5727
Genistein Alleviates Oxidative Stress and Inflammation in the Hypothalamic Paraventricular Nucleus by Activating the Sirt1/Nrf2 Pathway in High Salt-Induced Hypertension.
Niu LG, Sun N, Liu KL, Su Q, Qi J, Fu LY, Xin GR, Kang YM
Cardiovascular toxicology 2022 Nov;22(10-11):898-909
Cardiovascular toxicology 2022 Nov;22(10-11):898-909
Effect of Astragalus polysaccharides on the cryopreservation of goat semen.
Zhang X, Hu ZT, Li Y, Li YX, Xian M, Guo SM, Hu JH
Theriogenology 2022 Nov;193:47-57
Theriogenology 2022 Nov;193:47-57
Ellagic Acid Alleviates Mice Intestinal Ischemia-Reperfusion Injury: A Study Based on Transcriptomics Combined with Functional Experiments.
Fan S, Xu Y, Li K, Li B, Diao Y
Chemistry & biodiversity 2022 Nov;19(11):e202200345
Chemistry & biodiversity 2022 Nov;19(11):e202200345
Cognitive-exercise dual-task intervention ameliorates cognitive decline in natural aging rats through reducing oxidative stress and enhancing synaptic plasticity.
Li XL, Tao X, Li TC, Zhu ZM, Huang PL, Gong WJ
Experimental gerontology 2022 Nov;169:111981
Experimental gerontology 2022 Nov;169:111981
Mettl3 regulates hypertrophic differentiation of chondrocytes through modulating Dmp1 mRNA via Ythdf1-mediated m(6)A modification.
He Y, Wang W, Luo P, Wang Y, He Z, Dong W, Jia M, Yu X, Yang B, Wang J
Bone 2022 Nov;164:116522
Bone 2022 Nov;164:116522
Acetyl-Coenzyme A Synthetase 2 Potentiates Macropinocytosis and Muscle Wasting Through Metabolic Reprogramming in Pancreatic Cancer.
Zhou Z, Ren Y, Yang J, Liu M, Shi X, Luo W, Fung KM, Xu C, Bronze MS, Zhang Y, Houchen CW, Li M
Gastroenterology 2022 Nov;163(5):1281-1293.e1
Gastroenterology 2022 Nov;163(5):1281-1293.e1
Tnfaip2 promotes atherogenesis by enhancing oxidative stress induced inflammation.
Jin G, Liu Y, Xu W, Li Y, Zhang H, Qiu S, Gao C, Liu S
Molecular immunology 2022 Nov;151:41-51
Molecular immunology 2022 Nov;151:41-51
Transglutaminase 3 Attenuates Skin Inflammation in Psoriasis by Inhibiting NF-κB Activation through Phosphorylated STAT3-TET3 Signaling.
Ling S, Xu B, Luo Y, Fang X, Liu X, Wang A, Zhou Y, Zhang S, Zong W, Li W, Yao X
The Journal of investigative dermatology 2022 Nov;142(11):2968-2977.e10
The Journal of investigative dermatology 2022 Nov;142(11):2968-2977.e10
Functional analyses of two interferon-stimulated gene 15 (ISG15) copies in large yellow croaker, Larimichthys crocea.
Shen B, Zhang S, Li F, Xu J, Zhang Y, Zhang J
Fish & shellfish immunology 2022 Nov;130:530-537
Fish & shellfish immunology 2022 Nov;130:530-537
Diterpenoids from the whole plant of Euphorbia wallichii and their protective effects on H(2)O(2)-induced BV-2 microglial cells injury.
Wang Y, Zhu M, Liang J, Zhang N, Sun D, Li H, Chen L
Bioorganic chemistry 2022 Nov;128:106067
Bioorganic chemistry 2022 Nov;128:106067
Capsaicin suppresses hepatocarcinogenesis by inhibiting the stemness of hepatic progenitor cells via SIRT1/SOX2 signaling pathway.
Xie ZQ, Li HX, Hou XJ, Huang MY, Zhu ZM, Wei LX, Tang CX
Cancer medicine 2022 Nov;11(22):4283-4296
Cancer medicine 2022 Nov;11(22):4283-4296
Pectin supplementation ameliorates intestinal epithelial barrier function damage by modulating intestinal microbiota in lipopolysaccharide-challenged piglets.
Wen X, Zhong R, Dang G, Xia B, Wu W, Tang S, Tang L, Liu L, Liu Z, Chen L, Zhang H
The Journal of nutritional biochemistry 2022 Nov;109:109107
The Journal of nutritional biochemistry 2022 Nov;109:109107
Myo1b promotes tumor progression and angiogenesis by inhibiting autophagic degradation of HIF-1α in colorectal cancer.
Chen YH, Xu NZ, Hong C, Li WQ, Zhang YQ, Yu XY, Huang YL, Zhou JY
Cell death & disease 2022 Nov 8;13(11):939
Cell death & disease 2022 Nov 8;13(11):939
A dynamic fluorescence probed glycolysis suppression process in HeLa cells treated with trichostatin A.
Zhang F, Shao C, Wu Y, Zhao W, Jing X, Fang C, Huang Q
The Analyst 2022 Nov 7;147(22):5082-5090
The Analyst 2022 Nov 7;147(22):5082-5090
Kruppel-like factor 13 inhibits cell proliferation of gastric cancer by inducing autophagic degradation of β-catenin.
Ding Y, Xu Y, Fu Y, Zhang H, Zhao L, Fan X
Discover oncology 2022 Nov 6;13(1):121
Discover oncology 2022 Nov 6;13(1):121
Placenta-Targeted Nanoparticles Loaded with PFKFB3 Overexpression Plasmids Enhance Angiogenesis and Placental Function.
Li Q, Liu X, Liu W, Zhang Y, Liu W, Wu M, Chen Z, Zhao Y, Zou L
Bioengineering (Basel, Switzerland) 2022 Nov 4;9(11)
Bioengineering (Basel, Switzerland) 2022 Nov 4;9(11)
Trichostatin D as a Novel KLF2 Activator Attenuates TNFα-Induced Endothelial Inflammation.
Lei L, Chen M, Wang C, Jiang X, Li Y, Wang W, Li S, Zhao L, Sheng R, Han J, Zhang Y, Chen Y, Yan B, Wu Y, Yu L, Si S, Xu Y
International journal of molecular sciences 2022 Nov 3;23(21)
International journal of molecular sciences 2022 Nov 3;23(21)
Carbon dots derived from folic acid attenuates osteoarthritis by protecting chondrocytes through NF-κB/MAPK pathway and reprogramming macrophages.
Jin Y, Zhang Q, Qin X, Liu Z, Li Z, Zhong X, Xia L, He J, Fang B
Journal of nanobiotechnology 2022 Nov 3;20(1):469
Journal of nanobiotechnology 2022 Nov 3;20(1):469
Identification of circular RNA BTBD7_hsa_circ_0000563 as a novel biomarker for coronary artery disease and the functional discovery of BTBD7_hsa_circ_0000563 based on peripheral blood mononuclear cells: a case control study.
Zhou H, Gan X, He S, Wang Y, Zhang S, Chen J, Zhou Y, Hou C, Hua L, Zhang Q, Jia E
Clinical proteomics 2022 Nov 3;19(1):37
Clinical proteomics 2022 Nov 3;19(1):37
GRP75 Modulates Endoplasmic Reticulum-Mitochondria Coupling and Accelerates Ca(2+)-Dependent Endothelial Cell Apoptosis in Diabetic Retinopathy.
Li Y, Li HY, Shao J, Zhu L, Xie TH, Cai J, Wang W, Cai MX, Wang ZL, Yao Y, Wei TT
Biomolecules 2022 Nov 29;12(12)
Biomolecules 2022 Nov 29;12(12)
A Class I HDAC Inhibitor BG45 Alleviates Cognitive Impairment through the CaMKII/ITPKA/Ca(2+) Signaling Pathway.
Liu J, Zhang C, Wang J, Huang Y, Shen D, Hu Y, Chu H, Yu X, Zhang L, Ma H
Pharmaceuticals (Basel, Switzerland) 2022 Nov 28;15(12)
Pharmaceuticals (Basel, Switzerland) 2022 Nov 28;15(12)
MiR-145 inhibits the differentiation and proliferation of bone marrow stromal mesenchymal stem cells by GABARAPL1 in steroid-induced femoral head necrosis.
Xu P, Chang J, Ma G, Liao F, Xu T, Wu Y, Yin Z
BMC musculoskeletal disorders 2022 Nov 26;23(1):1020
BMC musculoskeletal disorders 2022 Nov 26;23(1):1020
A Novel High-Throughput Screening Method for a Human Multicentric Osteosarcoma-Specific Antibody and Biomarker Using a Phage Display-Derived Monoclonal Antibody.
Hayashi T, Yamamoto N, Kurosawa G, Tajima K, Kondo M, Hiramatsu N, Kato Y, Tanaka M, Yamaguchi H, Kurosawa Y, Yamada H, Fujita N
Cancers 2022 Nov 26;14(23)
Cancers 2022 Nov 26;14(23)
The Aurora Kinase Inhibitor TAK901 Inhibits Glioblastoma Growth by Blocking SREBP1-Mediated Lipid Metabolism.
Zhan X, Qiu R, He Y, Zhao Z, Huang M, Liu Q, Zhi F, Long W
Cancers 2022 Nov 25;14(23)
Cancers 2022 Nov 25;14(23)
Suffruticosol C-Mediated Autophagy and Cell Cycle Arrest via Inhibition of mTORC1 Signaling.
Qin S, Geng H, Wang G, Chen L, Xia C, Yao J, Bai Z, Deng L
Nutrients 2022 Nov 24;14(23)
Nutrients 2022 Nov 24;14(23)
Transmissible Gastroenteritis Virus Nucleocapsid Protein Interacts with Na(+)/H(+) Exchanger 3 To Reduce Na(+)/H(+) Exchanger Activity and Promote Piglet Diarrhea.
Niu Z, Xu S, Zhang Y, Kan Z, Zhang J, Liu X, Zhang S, Zou H, Song Z
Journal of virology 2022 Nov 23;96(22):e0147322
Journal of virology 2022 Nov 23;96(22):e0147322
PSMA1 mediates tumor progression and poor prognosis of gastric carcinoma by deubiquitinating and stabilizing TAZ.
Yang Q, Lu Y, Shangguan J, Shu X
Cell death & disease 2022 Nov 23;13(11):989
Cell death & disease 2022 Nov 23;13(11):989
JMJD1C Regulates Megakaryopoiesis in In Vitro Models through the Actin Network.
Wang J, Liu X, Wang H, Qin L, Feng A, Qi D, Wang H, Zhao Y, Kong L, Wang H, Wang L, Hu Z, Xu X
Cells 2022 Nov 18;11(22)
Cells 2022 Nov 18;11(22)
mTOR inhibition attenuates chemosensitivity through the induction of chemotherapy resistant persisters.
Liu Y, Azizian NG, Sullivan DK, Li Y
Nature communications 2022 Nov 17;13(1):7047
Nature communications 2022 Nov 17;13(1):7047
Autophagy Mediates Escherichia Coli-Induced Cellular Inflammatory Injury by Regulating Calcium Mobilization, Mitochondrial Dysfunction, and Endoplasmic Reticulum Stress.
Liu J, Qiu R, Liu R, Song P, Lin P, Chen H, Zhou D, Wang A, Jin Y
International journal of molecular sciences 2022 Nov 16;23(22)
International journal of molecular sciences 2022 Nov 16;23(22)
NNMT-DNMT1 Axis is Essential for Maintaining Cancer Cell Sensitivity to Oxidative Phosphorylation Inhibition.
Wu C, Liu Y, Liu W, Zou T, Lu S, Zhu C, He L, Chen J, Fang L, Zou L, Wang P, Fan L, Wang H, You H, Chen J, Fang JY, Jiang C, Shi Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Nov 16;10(1):e2202642
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Nov 16;10(1):e2202642
Inhibition of human peptide deformylase by actinonin sensitizes glioblastoma cells to temozolomide chemotherapy.
Lan B, Zhao H, He Y, Zhao Z, Wang N, Gao Y
Experimental cell research 2022 Nov 15;420(2):113358
Experimental cell research 2022 Nov 15;420(2):113358
Pu-erh tea increases the metabolite Cinnabarinic acid to improve circadian rhythm disorder-induced obesity.
Hu S, Hu C, Luo L, Zhang H, Zhao S, Liu Z, Zeng L
Food chemistry 2022 Nov 15;394:133500
Food chemistry 2022 Nov 15;394:133500
Qingfei oral liquid alleviates RSV-induced lung inflammation by promoting fatty-acid-dependent M1/M2 macrophage polarization via the Akt signaling pathway.
An L, Lu M, Xu W, Chen H, Feng L, Xie T, Shan J, Wang S, Lin L
Journal of ethnopharmacology 2022 Nov 15;298:115637
Journal of ethnopharmacology 2022 Nov 15;298:115637
A multi-target directed ligands strategy for the treatment of Alzheimer's disease: Dimethyl fumarate plus Tranilast modified Dithiocarbate as AChE inhibitor and Nrf2 activator.
Guo J, Cheng M, Liu P, Cao D, Luo J, Wan Y, Fang Y, Jin Y, Xie SS, Liu J
European journal of medicinal chemistry 2022 Nov 15;242:114630
European journal of medicinal chemistry 2022 Nov 15;242:114630
Salecan ameliorates liver injury by regulating gut microbiota and its metabolites.
Li P, Liu Y, Zhao J, Pan W, He Y, Fu S, Liu Y, Xu YJ
Food & function 2022 Nov 14;13(22):11744-11757
Food & function 2022 Nov 14;13(22):11744-11757
Targeting glutamine metabolism in hepatic stellate cells alleviates liver fibrosis.
Yin X, Peng J, Gu L, Liu Y, Li X, Wu J, Xu B, Zhuge Y, Zhang F
Cell death & disease 2022 Nov 14;13(11):955
Cell death & disease 2022 Nov 14;13(11):955
Protective Effect of Flavonoids against Methylglyoxal-Induced Oxidative Stress in PC-12 Neuroblastoma Cells and Its Structure-Activity Relationships.
Zhang D, Li X, He X, Xing Y, Jiang B, Xiu Z, Bao Y, Dong Y
Molecules (Basel, Switzerland) 2022 Nov 12;27(22)
Molecules (Basel, Switzerland) 2022 Nov 12;27(22)
Circular RNA hsa_circ_0051040 Promotes Hepatocellular Carcinoma Progression by Sponging miR-569 and Regulating ITGAV Expression.
Ju L, Yao M, Lu R, Cao Y, Wang H, Yuan L, Xiao F, Shao J, Cai W, Chen L, Bian Z
Cells 2022 Nov 11;11(22)
Cells 2022 Nov 11;11(22)
Rhodiola activates macrophage migration inhibitory factor to alleviate non-alcoholic fatty liver disease.
Liu J, Li D, Dun Y, Li H, Ripley-Gonzalez JW, Zhang J, Qiu L, You B, Liu S
Life sciences 2022 Nov 1;308:120949
Life sciences 2022 Nov 1;308:120949
Molecular and functional characterization of teleost-specific Interleukin-17N in yellow catfish (Pelteobagrus fulvidraco).
Zhou X, Jiang XX, Zhang GR, Ji W, Shi ZC, Ma XF, Wei KJ
International journal of biological macromolecules 2022 Nov 1;220:493-509
International journal of biological macromolecules 2022 Nov 1;220:493-509
Altered Liver Metabolism, Mitochondrial Function, Oxidative Status, and Inflammatory Response in Intrauterine Growth Restriction Piglets with Different Growth Patterns before Weaning.
Wang J, Zhu P, Zheng X, Ma Z, Cui C, Wu C, Zeng X, Guan W, Chen F
Metabolites 2022 Nov 1;12(11)
Metabolites 2022 Nov 1;12(11)
Silibinin improves L-cell mass and function through an estrogen receptor-mediated antioxidative mechanism.
Wang J, Zhang L, Cao H, Shi X, Zhang X, Gao Z, Ikeda K, Yan T, Jia Y, Xu F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:154022
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:154022
Unveiling the anti-senescence effects and senescence-associated secretory phenotype (SASP) inhibitory mechanisms of Scutellaria baicalensis Georgi in low glucose-induced astrocytes based on boolean network.
Gao L, Yang WY, Qi H, Sun CJ, Qin XM, Du GH
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:153990
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:153990
Jumonji-C domain-containing protein 5 suppresses proliferation and aerobic glycolysis in pancreatic cancer cells in a c-Myc-dependent manner.
Wang H, Wang J, Liu J, Wang Y, Xia G, Huang X
Cellular signalling 2022 May;93:110282
Cellular signalling 2022 May;93:110282
Astrocytic p75(NTR) expression provoked by ischemic stroke exacerbates the blood-brain barrier disruption.
Qin X, Wang J, Chen S, Liu G, Wu C, Lv Q, He X, Bai X, Huang W, Liao H
Glia 2022 May;70(5):892-912
Glia 2022 May;70(5):892-912
Macamide B Pretreatment Attenuates Neonatal Hypoxic-Ischemic Brain Damage of Mice Induced Apoptosis and Regulates Autophagy via the PI3K/AKT Signaling Pathway.
Yang X, Wang M, Zhou Q, Bai Y, Liu J, Yang J, Li L, Li G, Luo L
Molecular neurobiology 2022 May;59(5):2776-2798
Molecular neurobiology 2022 May;59(5):2776-2798
Candida albicans induces upregulation of programmed death ligand 1 in oral squamous cell carcinoma.
Wang X, Zhao W, Zhang W, Wu S, Yan Z
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2022 May;51(5):444-453
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2022 May;51(5):444-453
Transcriptome Profiling Analysis Identifies LCP1 as a Contributor for Chidamide Resistance in Gastric Cancer.
Bao W, Zhu Z, Gao Y, Chen J
Pharmaceutical research 2022 May;39(5):867-876
Pharmaceutical research 2022 May;39(5):867-876
Nrf2 improves hippocampal synaptic plasticity, learning and memory through the circ-Vps41/miR-26a-5p/CaMKIV regulatory network.
Zhang R, Gao Y, Li Y, Geng D, Liang Y, He Q, Wang L, Cui H
Experimental neurology 2022 May;351:113998
Experimental neurology 2022 May;351:113998
Minocycline Pretreatment Prevents Blood-Brain Barrier Disruption in Septic Rats.
Yang G, Cao Y, Wang P, Mei L, Chen J, Lu W
The Journal of surgical research 2022 May;273:247-254
The Journal of surgical research 2022 May;273:247-254
Venetoclax enhances DNA damage induced by XPO1 inhibitors: A novel mechanism underlying the synergistic antileukaemic effect in acute myeloid leukaemia.
Yu H, Wu S, Liu S, Li X, Gai Y, Lin H, Wang Y, Edwards H, Ge Y, Wang G
Journal of cellular and molecular medicine 2022 May;26(9):2646-2657
Journal of cellular and molecular medicine 2022 May;26(9):2646-2657
NEDD4 attenuates phosgene-induced acute lung injury through the inhibition of Notch1 activation.
Shao Y, Jiang Z, He D, Shen J
Journal of cellular and molecular medicine 2022 May;26(10):2831-2840
Journal of cellular and molecular medicine 2022 May;26(10):2831-2840
Calpain-1 mediates vascular remodelling and fibrosis via HIF-1α in hypoxia-induced pulmonary hypertension.
Deng H, Tian X, Sun H, Liu H, Lu M, Wang H
Journal of cellular and molecular medicine 2022 May;26(10):2819-2830
Journal of cellular and molecular medicine 2022 May;26(10):2819-2830
ANKRD37 inhibits trophoblast migration and invasion by regulating the NF-κB pathway in preeclampsia.
Tan W, Fu H, Zhou X, Duan Y, Yin N, Huang J, Liu X
The journal of gene medicine 2022 May;24(5):e3416
The journal of gene medicine 2022 May;24(5):e3416
Long noncoding RNA GAS5 inhibits proliferation and metastasis in papillary thyroid carcinoma through the IFN/STAT1 signaling pathway.
Xu Y, Lu J, Lou N, Lu W, Xu J, Jiang H, Ye G
Pathology, research and practice 2022 May;233:153856
Pathology, research and practice 2022 May;233:153856
MicroRNA-20a promotes non-small cell lung cancer proliferation by upregulating PD-L1 by targeting PTEN.
Gong J, Shen Y, Jiang F, Wang Y, Chu L, Sun J, Shen P, Chen M
Oncology letters 2022 May;23(5):148
Oncology letters 2022 May;23(5):148
PM(2.5) induced lung injury through upregulating ROS-dependent NLRP3 Inflammasome-Mediated Pyroptosis.
Ren F, Xu J, Zhang J, Xu X, Huang L, Sun W, Li R, Li F
Immunobiology 2022 May;227(3):152207
Immunobiology 2022 May;227(3):152207
Zinc Alleviates Arsenic-Induced Inflammation and Apoptosis in the Head Kidney of Common Carp by Inhibiting Oxidative Stress and Endoplasmic Reticulum Stress.
Xing P, Zhang Y, Chi Q, Li S
Biological trace element research 2022 May;200(5):2380-2390
Biological trace element research 2022 May;200(5):2380-2390
Sodium tanshinone IIA sulfonate enhances the BMP9-BMPR2-Smad1/5/9 signaling pathway in rat pulmonary microvascular endothelial cells and human embryonic stem cell-derived endothelial cells.
Wang J, Liu W, Lu W, Luo X, Lin Y, Liu S, Qian J, Zhang C, Chen H, Li Y, Li X, Chen J, Chen Y, Jiang Q, Liu C, Hong C, Wang T, Tang H, Zhong N, Yang J, Yang K, Sun D
Biochemical pharmacology 2022 May;199:114986
Biochemical pharmacology 2022 May;199:114986
Ghrelin ameliorates diabetes-associated behavioral deficits and NLRP3 inflammasome activation via autophagic flux enhancement.
Han W, Cui C, Zhang H, Guo Y, Xie D, Zhang W, Wang C, Yang M, Jiang P
Pharmacological research 2022 May;179:106224
Pharmacological research 2022 May;179:106224
Angiotensin-(1-7) improves diabetes mellitus-induced erectile dysfunction in rats by regulating nitric oxide synthase levels.
Xu Y, Zhang F, Li C, Hao H, Hao Y
Peptides 2022 May;151:170765
Peptides 2022 May;151:170765
Mitochondrial transcription factor B2 overexpression increases M2 macrophage infiltration via cytosolic mitochondrial DNA-stimulated Interleukin-6 secretion in ovarian cancer.
Wu W, Zhou S, Liu T, Liang D
Bioengineered 2022 May;13(5):12211-12223
Bioengineered 2022 May;13(5):12211-12223
A novel hypoxia-driven gene signature that can predict the prognosis of hepatocellular carcinoma.
Zeng Z, Lei S, Wang J, Yang Y, Lan J, Tian Q, Chen T, Hao X
Bioengineered 2022 May;13(5):12193-12210
Bioengineered 2022 May;13(5):12193-12210
Circular RNA CircSHKBP1 accelerates the proliferation, invasion, angiogenesis, and stem cell-like properties via modulation of microR-766-5p/high mobility group AT-hook 2 axis in laryngeal squamous cell carcinoma.
Chen F, Zhang H, Wang J
Bioengineered 2022 May;13(5):11551-11563
Bioengineered 2022 May;13(5):11551-11563
Extracellular vesicles rich in HAX1 promote angiogenesis by modulating ITGB6 translation.
You B, Pan S, Gu M, Zhang K, Xia T, Zhang S, Chen W, Xie H, Fan Y, Yao H, Cheng T, Zhang P, Liu D, You Y
Journal of extracellular vesicles 2022 May;11(5):e12221
Journal of extracellular vesicles 2022 May;11(5):e12221
SIRT3-AMPK signaling pathway as a protective target in endothelial dysfunction of early sepsis.
Yu H, Liu Q, Chen G, Huang L, Luo M, Lv D, Luo S
International immunopharmacology 2022 May;106:108600
International immunopharmacology 2022 May;106:108600
HIF-1α inhibition attenuates severity of Achilles tendinopathy by blocking NF-κB and MAPK pathways.
Jiao X, Zhang Y, Li W, Zhou X, Chu W, Li Y, Wang Z, Sun X, Xu C, Gan Y
International immunopharmacology 2022 May;106:108543
International immunopharmacology 2022 May;106:108543
Deletion of MTAP Highly Sensitizes Osteosarcoma Cells to Methionine Restriction With Recombinant Methioninase.
Aoki Y, Tome Y, Han Q, Yamamoto J, Hamada K, Masaki N, Kubota Y, Bouvet M, Nishida K, Hoffman RM
Cancer genomics & proteomics 2022 May-Jun;19(3):299-304
Cancer genomics & proteomics 2022 May-Jun;19(3):299-304
Glucolipotoxicity induces endothelial cell dysfunction by activating autophagy and inhibiting autophagic flow.
Liu Y, Xiang H, Xiong W, Ouyang J, Liu H, Zhao S, Xiao J, Li J, Shu Z, Wang X, Liu H, Zhang J, Fan J, Li Y, Chen S, Lu H
Diabetes & vascular disease research 2022 May-Jun;19(3):14791641221102513
Diabetes & vascular disease research 2022 May-Jun;19(3):14791641221102513
A High-Fat Diet Induces Muscle Mitochondrial Dysfunction and Impairs Swimming Capacity in Zebrafish: A New Model of Sarcopenic Obesity.
Zou YY, Chen ZL, Sun CC, Yang D, Zhou ZQ, Xiao Q, Peng XY, Tang CF
Nutrients 2022 May 9;14(9)
Nutrients 2022 May 9;14(9)
Hypoxic mesenchymal stem cell-derived extracellular vesicles ameliorate renal fibrosis after ischemia-reperfusion injure by restoring CPT1A mediated fatty acid oxidation.
Gao Z, Zhang C, Peng F, Chen Q, Zhao Y, Chen L, Wang X, Chen X
Stem cell research & therapy 2022 May 7;13(1):191
Stem cell research & therapy 2022 May 7;13(1):191
GLUT5-KHK axis-mediated fructose metabolism drives proliferation and chemotherapy resistance of colorectal cancer.
Shen Z, Li Z, Liu Y, Li Y, Feng X, Zhan Y, Lin M, Fang C, Fang Y, Deng H
Cancer letters 2022 May 28;534:215617
Cancer letters 2022 May 28;534:215617
Therapeutic targeting m6A-guided miR-146a-5p signaling contributes to the melittin-induced selective suppression of bladder cancer.
Yan R, Dai W, Wu R, Huang H, Shu M
Cancer letters 2022 May 28;534:215615
Cancer letters 2022 May 28;534:215615
Resveratrol pretreatment protects neurons from oxygen-glucose deprivation/reoxygenation and ischemic injury through inhibiting ferroptosis.
Zhu H, Huang J, Chen Y, Li X, Wen J, Tian M, Ren J, Zhou L, Yang Q
Bioscience, biotechnology, and biochemistry 2022 May 24;86(6):704-716
Bioscience, biotechnology, and biochemistry 2022 May 24;86(6):704-716
Impact of Selective Renal Afferent Denervation on Oxidative Stress and Vascular Remodeling in Spontaneously Hypertensive Rats.
Wu LL, Zhang Y, Li XZ, Du XL, Gao Y, Wang JX, Wang XL, Chen Q, Li YH, Zhu GQ, Tan X
Antioxidants (Basel, Switzerland) 2022 May 20;11(5)
Antioxidants (Basel, Switzerland) 2022 May 20;11(5)
Iron-dependent epigenetic modulation promotes pathogenic T cell differentiation in lupus.
Gao X, Song Y, Wu J, Lu S, Min X, Liu L, Hu L, Zheng M, Du P, Yu Y, Long H, Wu H, Jia S, Yu D, Lu Q, Zhao M
The Journal of clinical investigation 2022 May 2;132(9)
The Journal of clinical investigation 2022 May 2;132(9)
Triad3A-Dependent TLR4 Ubiquitination and Degradation Contributes to the Anti-Inflammatory Effects of Pterostilbene on Vascular Dementia.
Xu J, Liu J, Mi Y, Zhao T, Mu D, Meng Q, Wang F, Li N, Hou Y
Journal of agricultural and food chemistry 2022 May 18;70(19):5896-5910
Journal of agricultural and food chemistry 2022 May 18;70(19):5896-5910
Characterization of two novel knock-in mouse models of syndromic retinal ciliopathy carrying hypomorphic Sdccag8 mutations.
Ren ZL, Zhang HB, Li L, Yang ZL, Jiang L
Zoological research 2022 May 18;43(3):442-456
Zoological research 2022 May 18;43(3):442-456
A novel protein encoded by ZCRB1-induced circHEATR5B suppresses aerobic glycolysis of GBM through phosphorylation of JMJD5.
Song J, Zheng J, Liu X, Dong W, Yang C, Wang D, Ruan X, Zhao Y, Liu L, Wang P, Zhang M, Liu Y
Journal of experimental & clinical cancer research : CR 2022 May 10;41(1):171
Journal of experimental & clinical cancer research : CR 2022 May 10;41(1):171
The underlying rationality of Chinese medicine herb pair Coptis chinensis and Dolomiaea souliei: From the perspective of metabolomics and intestinal function.
Wang T, Zhang C, Li H, Zhou R, Ye X, Yang Y, He K
Journal of ethnopharmacology 2022 May 10;289:115065
Journal of ethnopharmacology 2022 May 10;289:115065
Old targets, new strategy: Apigenin-7-O-β-d-(-6″-p-coumaroyl)-glucopyranoside prevents endothelial ferroptosis and alleviates intestinal ischemia-reperfusion injury through HO-1 and MAO-B inhibition.
Feng YD, Ye W, Tian W, Meng JR, Zhang M, Sun Y, Zhang HN, Wang SJ, Wu KH, Liu CX, Liu SY, Cao W, Li XQ
Free radical biology & medicine 2022 May 1;184:74-88
Free radical biology & medicine 2022 May 1;184:74-88
ATRX-dependent SVCT2 mediates macrophage infiltration in the glioblastoma xenograft model.
Shang J, Wang Y, Li Z, Jiang L, Bai Q, Zhang X, Xiao G, Zhang J
Journal of neurophysiology 2022 May 1;127(5):1309-1316
Journal of neurophysiology 2022 May 1;127(5):1309-1316
Sheng Mai San ameliorated heat stress-induced liver injury via regulating energy metabolism and AMPK/Drp1-dependent autophagy process.
Zhang X, Jia Y, Yuan Z, Wen Y, Zhang Y, Ren J, Ji P, Yao W, Hua Y, Wei Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Mar;97:153920
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Mar;97:153920
Integrated multi-omics analysis reveals miR-20a as a regulator for metabolic colorectal cancer.
Song K, Liu C, Zhang J, Yao Y, Xiao H, Yuan R, Li K, Yang J, Zhao W, Zhang Y
Heliyon 2022 Mar;8(3):e09068
Heliyon 2022 Mar;8(3):e09068
Heat stress-induced mucosal barrier dysfunction is potentially associated with gut microbiota dysbiosis in pigs.
Xia B, Wu W, Fang W, Wen X, Xie J, Zhang H
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Mar;8(1):289-299
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Mar;8(1):289-299
NCAPH regulates gastric cancer progression through DNA damage response.
Wang Y, Li JQ, Yang ZL, Wang L, Zhang JC, Sun YF, Li ZY, Qin L
Neoplasma 2022 Mar;69(2):283-291
Neoplasma 2022 Mar;69(2):283-291
Ferroptosis promotes microtubule-associated protein tau aggregation via GSK-3β activation and proteasome inhibition.
Wang S, Jiang Y, Liu Y, Liu Q, Sun H, Mei M, Liao X
Molecular neurobiology 2022 Mar;59(3):1486-1501
Molecular neurobiology 2022 Mar;59(3):1486-1501
Cytosine-phosphate-guanine oligodeoxynucleotides regulate the cell cycle, apoptosis, and steroidogenesis of mouse ovarian granulosa cells by targeting inhibin alpha (1 ~ 32) fragments.
Yang M, Feng J, Lan X, Tang Y, Zhang Y, Zhang H, Wang S
In vitro cellular & developmental biology. Animal 2022 Mar;58(3):243-254
In vitro cellular & developmental biology. Animal 2022 Mar;58(3):243-254
Effects of 4-vinylcyclohexene diepoxide on the cell cycle, apoptosis, and steroid hormone secretion of goat ovarian granulosa cells.
Miao Y, Wan W, Zhu K, Pan M, Zhao X, Ma B, Wei Q
In vitro cellular & developmental biology. Animal 2022 Mar;58(3):220-231
In vitro cellular & developmental biology. Animal 2022 Mar;58(3):220-231
NLRP3 Inflammasome Activation Enhances ADK Expression to Accelerate Epilepsy in Mice.
Zhang H, Yu S, Xia L, Peng X, Wang S, Yao B
Neurochemical research 2022 Mar;47(3):713-722
Neurochemical research 2022 Mar;47(3):713-722
HPV16 E6/E7 stabilize PGK1 protein by reducing its poly-ubiquitination in cervical cancer.
Liu S, Song L, Yao H, Zhang L
Cell biology international 2022 Mar;46(3):370-380
Cell biology international 2022 Mar;46(3):370-380
DNA damage-induced translocation of mitochondrial factor HIGD1A into the nucleus regulates homologous recombination and radio/chemo-sensitivity.
Chen B, Xu F, Gao Y, Hu G, Zhu K, Lu H, Xu A, Chen S, Wu L, Zhao G
Oncogene 2022 Mar;41(13):1918-1930
Oncogene 2022 Mar;41(13):1918-1930
O-GlcNAc modification mediates aquaporin 3 to coordinate endometrial cell glycolysis and affects embryo implantation.
Zhang H, Qi J, Pei J, Zhang M, Shang Y, Li Z, Wang Y, Guo J, Sun K, Fan J, Sui L, Xu Y, Kong L, Kong Y
Journal of advanced research 2022 Mar;37:119-131
Journal of advanced research 2022 Mar;37:119-131
A positive feedback circuit comprising p21 and HIF-1α aggravates hypoxia-induced radioresistance of glioblastoma by promoting Glut1/LDHA-mediated glycolysis.
Jin X, Kuang Y, Li L, Li H, Zhao T, He Y, Di C, Kang J, Yuan L, Yu B, Li Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Mar;36(3):e22229
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Mar;36(3):e22229
Pseudorabies virus kinase UL13 phosphorylates H2AX to foster viral replication.
Ming X, Bo Z, Miao Y, Chen H, Bao C, Sun L, Xi R, Zhong Q, Zhao P, Jung YS, Qian Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Mar;36(3):e22221
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Mar;36(3):e22221
Costunolide protects against alcohol-induced liver injury by regulating gut microbiota, oxidative stress and attenuating inflammation in vivo and in vitro.
Mao J, Zhan H, Meng F, Wang G, Huang D, Liao Z, Chen M
Phytotherapy research : PTR 2022 Mar;36(3):1268-1283
Phytotherapy research : PTR 2022 Mar;36(3):1268-1283
Injectable hydrogel with nucleus pulposus-matched viscoelastic property prevents intervertebral disc degeneration.
Jia H, Lin X, Wang D, Wang J, Shang Q, He X, Wu K, Zhao B, Peng P, Wang H, Wang D, Li P, Yang L, Luo Z, Yang L
Journal of orthopaedic translation 2022 Mar;33:162-173
Journal of orthopaedic translation 2022 Mar;33:162-173
Arsenic exposure via drinking water during pregnancy and lactation induces autism-like behaviors in male offspring mice.
Zhang X, Mei D, Li Y, You M, Wang D, Yao D, Xu Y, Zhai L, Wang Y
Chemosphere 2022 Mar;290:133338
Chemosphere 2022 Mar;290:133338
Moxibustion alleviates decreased ovarian reserve in rats by restoring the PI3K/AKT signaling pathway.
Li HX, Shi L, Liang SJ, Fang CC, Xu QQ, Lu G, Wang Q, Cheng J, Shen J, Shen MH
Journal of integrative medicine 2022 Mar;20(2):163-172
Journal of integrative medicine 2022 Mar;20(2):163-172
HMGB2 causes photoreceptor death via down-regulating Nrf2/HO-1 and up-regulating NF-κB/NLRP3 signaling pathways in light-induced retinal degeneration model.
Zhang Y, Zhao Z, Zhao X, Xie H, Zhang C, Sun X, Zhang J
Free radical biology & medicine 2022 Mar;181:14-28
Free radical biology & medicine 2022 Mar;181:14-28
Alterations in the expression level of visfatin in the lungs of piglets infected with PRRSV and its effect on PRRSV replication.
Zhang ZW, Ansari AR, Dong L, Niu XY, Yang WJ, Li HZ, Xu FL, Yang KL, Song H
Microbial pathogenesis 2022 Mar;164:105443
Microbial pathogenesis 2022 Mar;164:105443
SiRNA-circFARSA-loaded porous silicon nanomaterials for pancreatic cancer treatment via inhibition of CircFARSA expression.
Yuan H, Huang X, Li Q, Luo C, Lin C, Zhang S, Zhang Y, Yan Z, Du N, Liu Z, Jiang H, Chen B
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Mar;147:112672
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Mar;147:112672
Improvement of tube formation model of cell: Application for acute hypoxia in in vitro study of angiogenesis.
Li F, Gou X, Xu D, Han D, Hou K, Fang W, Li Y
Microvascular research 2022 Mar;140:104297
Microvascular research 2022 Mar;140:104297
Injectable multifunctional CMC/HA-DA hydrogel for repairing skin injury.
Cui L, Li J, Guan S, Zhang K, Zhang K, Li J
Materials today. Bio 2022 Mar;14:100257
Materials today. Bio 2022 Mar;14:100257
Shikonin induces apoptosis and autophagy via downregulation of pyrroline-5-carboxylate reductase1 in hepatocellular carcinoma cells.
Zhang J, Shang L, Jiang W, Wu W
Bioengineered 2022 Mar;13(3):7904-7918
Bioengineered 2022 Mar;13(3):7904-7918
The protective effects of butorphanol tartrate against homocysteine-induced blood-brain barrier dysfunction.
Shen S, Wang J, Zhao Q, Hu Q
Bioengineered 2022 Mar;13(3):7209-7220
Bioengineered 2022 Mar;13(3):7209-7220
MYB proto-oncogene like 2 promotes hepatocellular carcinoma growth and glycolysis via binding to the Optic atrophy 3 promoter and activating its expression.
Liu M, Du Q, Mao G, Dai N, Zhang F
Bioengineered 2022 Mar;13(3):5344-5356
Bioengineered 2022 Mar;13(3):5344-5356
Klotho alleviates NLRP3 inflammasome-mediated neuroinflammation in a temporal lobe epilepsy rat model by activating the Nrf2 signaling pathway.
Xiang T, Luo X, Ye L, Huang H, Wu Y
Epilepsy & behavior : E&B 2022 Mar;128:108509
Epilepsy & behavior : E&B 2022 Mar;128:108509
Downregulation of NCL attenuates tumor formation and growth in HeLa cells by targeting the PI3K/AKT pathway.
Ying J, Pan R, Tang Z, Zhu J, Ren P, Lou Y, Zhang E, Huang D, Hu P, Li D, Bao Q, Li P
Cancer medicine 2022 Mar;11(6):1454-1464
Cancer medicine 2022 Mar;11(6):1454-1464
Venetoclax enhances NK cell killing sensitivity of AML cells through the NKG2D/NKG2DL activation pathway.
Wu HY, Li KX, Pan WY, Guo MQ, Qiu DZ, He YJ, Li YH, Huang YX
International immunopharmacology 2022 Mar;104:108497
International immunopharmacology 2022 Mar;104:108497
Sphingomyelin-Sequestered Cholesterol Domain Recruits Formin-Binding Protein 17 for Constricting Clathrin-Coated Pits in Influenza Virus Entry.
Tang B, Sun EZ, Zhang ZL, Liu SL, Liu J, Kusumi A, Hu ZH, Zeng T, Kang YF, Tang HW, Pang DW
Journal of virology 2022 Mar 9;96(5):e0181321
Journal of virology 2022 Mar 9;96(5):e0181321
The effects of angiotensin I-converting enzyme inhibitory peptide VGINYW and the hydrolysate of α-lactalbumin on blood pressure, oxidative stress and gut microbiota of spontaneously hypertensive rats.
Xie D, Shen Y, Su E, Du L, Xie J, Wei D
Food & function 2022 Mar 7;13(5):2743-2755
Food & function 2022 Mar 7;13(5):2743-2755
Fucoidan protects the pancreas and improves glucose metabolism through inhibiting inflammation and endoplasmic reticulum stress in T2DM rats.
Liu Y, Huang H, Xu Z, Xue Y, Zhang D, Zhang Y, Li W, Li X
Food & function 2022 Mar 7;13(5):2693-2709
Food & function 2022 Mar 7;13(5):2693-2709
Multifunctional photodynamic/photothermal nano-agents for the treatment of oral leukoplakia.
Lin L, Song C, Wei Z, Zou H, Han S, Cao Z, Zhang X, Zhang G, Ran J, Cai Y, Han W
Journal of nanobiotechnology 2022 Mar 4;20(1):106
Journal of nanobiotechnology 2022 Mar 4;20(1):106
N-myristoyltransferase-1 deficiency blocks myristoylation of LAMTOR1 and inhibits bladder cancer progression.
Sun Y, Guan Z, Sheng Q, Duan W, Zhao H, Zhou J, Deng Q, Pei X
Cancer letters 2022 Mar 31;529:126-138
Cancer letters 2022 Mar 31;529:126-138
Nuciferine Inhibits TMEM16A in Dietary Adjuvant Therapy for Lung Cancer.
Bai X, Liu X, Li S, An H, Kang X, Guo S
Journal of agricultural and food chemistry 2022 Mar 30;70(12):3687-3696
Journal of agricultural and food chemistry 2022 Mar 30;70(12):3687-3696
Thermosensitive Hydrogel Incorporating Prussian Blue Nanoparticles Promotes Diabetic Wound Healing via ROS Scavenging and Mitochondrial Function Restoration.
Xu Z, Liu Y, Ma R, Chen J, Qiu J, Du S, Li C, Wu Z, Yang X, Chen Z, Chen T
ACS applied materials & interfaces 2022 Mar 30;14(12):14059-14071
ACS applied materials & interfaces 2022 Mar 30;14(12):14059-14071
Pseudorabies Virus Inhibits Expression of Liver X Receptors to Assist Viral Infection.
Wang Y, Li GL, Qi YL, Li LY, Wang LF, Wang CR, Niu XR, Liu TX, Wang J, Yang GY, Zeng L, Chu BB
Viruses 2022 Mar 3;14(3)
Viruses 2022 Mar 3;14(3)
Discovery of Potent PROTACs Targeting EGFR Mutants through the Optimization of Covalent EGFR Ligands.
Zhao HY, Wang HP, Mao YZ, Zhang H, Xin M, Xi XX, Lei H, Mao S, Li DH, Zhang SQ
Journal of medicinal chemistry 2022 Mar 24;65(6):4709-4726
Journal of medicinal chemistry 2022 Mar 24;65(6):4709-4726
Inhibition of Metastatic Hepatocarcinoma by Combined Chemotherapy with Silencing VEGF/VEGFR2 Genes through a GalNAc-Modified Integrated Therapeutic System.
Li X, Wang X, Liu N, Wang Q, Hu J
Molecules (Basel, Switzerland) 2022 Mar 24;27(7)
Molecules (Basel, Switzerland) 2022 Mar 24;27(7)
The "LLQY" Motif on SARS-CoV-2 Spike Protein Affects S Incorporation into Virus Particles.
Du S, Xu W, Wang Y, Li L, Hao P, Tian M, Wang M, Li T, Wu S, Liu Q, Bai J, Qu X, Jin N, Zhou B, Liao M, Li C
Journal of virology 2022 Mar 23;96(6):e0189721
Journal of virology 2022 Mar 23;96(6):e0189721
A Dual Anti-Inflammatory and Anti-Proliferative 3-Styrylchromone Derivative Synergistically Enhances the Anti-Cancer Effects of DNA-Damaging Agents on Colon Cancer Cells by Targeting HMGB1-RAGE-ERK1/2 Signaling.
Tanuma SI, Oyama T, Okazawa M, Yamazaki H, Takao K, Sugita Y, Amano S, Abe T, Sakagami H
International journal of molecular sciences 2022 Mar 22;23(7)
International journal of molecular sciences 2022 Mar 22;23(7)
Progranulin improves neural development via the PI3K/Akt/GSK-3β pathway in the cerebellum of a VPA-induced rat model of ASD.
Wang L, Chen J, Hu Y, Liao A, Zheng W, Wang X, Lan J, Shen J, Wang S, Yang F, Wang Y, Li Y, Chen D
Translational psychiatry 2022 Mar 22;12(1):114
Translational psychiatry 2022 Mar 22;12(1):114
Dioscin relieves diabetic nephropathy via suppressing oxidative stress and apoptosis, and improving mitochondrial quality and quantity control.
Zhong Y, Liu J, Sun D, Guo T, Yao Y, Xia X, Shi C, Peng X
Food & function 2022 Mar 21;13(6):3660-3673
Food & function 2022 Mar 21;13(6):3660-3673
BMP-7 ameliorates partial epithelial-mesenchymal transition by restoring SnoN protein level via Smad1/5 pathway in diabetic kidney disease.
Peng W, Zhou X, Xu T, Mao Y, Zhang X, Liu H, Liang L, Liu L, Liu L, Xiao Y, Zhang F, Li S, Shi M, Zhou Y, Tang L, Wang Y, Guo B
Cell death & disease 2022 Mar 21;13(3):254
Cell death & disease 2022 Mar 21;13(3):254
Effects of iron oxide nanoparticles as T(2)-MRI contrast agents on reproductive system in male mice.
Yang H, Wang H, Wen C, Bai S, Wei P, Xu B, Xu Y, Liang C, Zhang Y, Zhang G, Wen H, Zhang L
Journal of nanobiotechnology 2022 Mar 2;20(1):98
Journal of nanobiotechnology 2022 Mar 2;20(1):98
p62 Promotes the Mitochondrial Localization of p53 through Its UBA Domain and Participates in Regulating the Sensitivity of Ovarian Cancer Cells to Cisplatin.
Kong Q, Yan X, Cheng M, Jiang X, Xu L, Shen L, Yu H, Sun L
International journal of molecular sciences 2022 Mar 18;23(6)
International journal of molecular sciences 2022 Mar 18;23(6)
lncRNA SNHG26 promoted the growth, metastasis, and cisplatin resistance of tongue squamous cell carcinoma through PGK1/Akt/mTOR signal pathway.
Jiang Q, Wang Z, Qi Q, Li J, Xin Y, Qiu J
Molecular therapy oncolytics 2022 Mar 17;24:355-370
Molecular therapy oncolytics 2022 Mar 17;24:355-370
Long noncoding RNA H19 mediates neural stem/progenitor cells proliferation, differentiation and apoptosis through the p53 signaling pathway after ischemic stroke.
Gan L, Liao S, Tong Y, Li W, Peng W, Deng S
Biochemical and biophysical research communications 2022 Mar 15;597:8-15
Biochemical and biophysical research communications 2022 Mar 15;597:8-15
Chelerythrine inhibits the progression of glioblastoma by suppressing the TGFB1-ERK1/2/Smad2/3-Snail/ZEB1 signaling pathway.
Zhu M, Niu J, Jiang J, Dong T, Chen Y, Yang X, Liu P
Life sciences 2022 Mar 15;293:120358
Life sciences 2022 Mar 15;293:120358
Fucoidan ameliorates glucose metabolism by the improvement of intestinal barrier and inflammatory damage in type 2 diabetic rats.
Liu Y, Xu Z, Huang H, Xue Y, Zhang D, Zhang Y, Li W, Li X
International journal of biological macromolecules 2022 Mar 15;201:616-629
International journal of biological macromolecules 2022 Mar 15;201:616-629
DL-3-n-butylphthalide imparts neuroprotection via Nrf2/SIRT3 pathway in a mouse model of vascular dementia.
Gao L, Guo X, Liu S, Sun Q, Qin X, Lv P, Hu M, Xu J, Dong Y
Brain research 2022 Mar 15;1779:147785
Brain research 2022 Mar 15;1779:147785
The Effects and Mechanisms of the Rapamycin-eluting Stent in Urethral Stricture Prevention in Rabbits.
Zhang T, Zhao W, Ren T, Chen J, Chen Z, Wang Y, Cheng X, Wu J, Yuan C, He T
Balkan medical journal 2022 Mar 14;39(2):107-114
Balkan medical journal 2022 Mar 14;39(2):107-114
The Novel Competing Endogenous Long Noncoding RNA SM2 Regulates Gonadotropin Secretion in the Hu Sheep Anterior Pituitary by Targeting the Oar-miR-16b/TGF-β/SMAD2 Signaling Pathway.
Wan Z, Yang H, Chen P, Wang Z, Cai Y, Yao X, Wang F, Zhang Y
Cells 2022 Mar 14;11(6)
Cells 2022 Mar 14;11(6)
Delivery of nVEGFi using AAV8 for the treatment of neovascular age-related macular degeneration.
She K, Su J, Wang Q, Liu Y, Zhong X, Jin X, Zhao Q, Xiao J, Li R, Deng H, Lu F, Yang Y, Wei Y
Molecular therapy. Methods & clinical development 2022 Mar 10;24:210-221
Molecular therapy. Methods & clinical development 2022 Mar 10;24:210-221
Transplantation of Human Umbilical Cord Mesenchymal Stem Cells-Derived Neural Stem Cells Pretreated with Neuregulin1β Ameliorate Cerebral Ischemic Reperfusion Injury in Rats.
Zhai QY, Ren YQ, Ni QS, Song ZH, Ge KL, Guo YL
Biomolecules 2022 Mar 10;12(3)
Biomolecules 2022 Mar 10;12(3)
Autophagy and mitochondrial dynamics contribute to the protective effect of diosgenin against 3-MCPD induced kidney injury.
Zhong Y, Sun D, Yao Y, Liu Q, Guo T, Wang X, Peng X
Chemico-biological interactions 2022 Mar 1;355:109850
Chemico-biological interactions 2022 Mar 1;355:109850
Systematic characterization of the metabolites of defatted walnut powder extract in vivo and screening of the mechanisms against NAFLD by UPLC-Q-Exactive Orbitrap MS combined with network pharmacology.
Ren SM, Zhang QZ, Jiang M, Chen ML, Xu XJ, Wang DM, Pan YN, Liu XQ
Journal of ethnopharmacology 2022 Mar 1;285:114870
Journal of ethnopharmacology 2022 Mar 1;285:114870
Panax notoginseng saponins protect PC12 cells against Aβ induced injury via promoting parkin-mediated mitophagy.
Jiang Y, Li H, Huang P, Li S, Li B, Huo L, Zhong J, Pan Z, Li Y, Xia X
Journal of ethnopharmacology 2022 Mar 1;285:114859
Journal of ethnopharmacology 2022 Mar 1;285:114859
Oxidative stress activates Ryr2-Ca(2+) and apoptosis to promote PM(2.5)-induced heart injury of hyperlipidemia mice.
Meng M, Jia R, Wei M, Meng X, Zhang X, Du R, Sun W, Wang L, Song L
Ecotoxicology and environmental safety 2022 Mar 1;232:113228
Ecotoxicology and environmental safety 2022 Mar 1;232:113228
Endothelial Cells Mediated by UCP2 Control the Neurogenic-to-Astrogenic Neural Stem Cells Fate Switch During Brain Development.
Wang W, Su L, Wang Y, Li C, Ji F, Jiao J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jun;9(18):e2105208
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jun;9(18):e2105208
LINC01534/miR-135b-5p/PTPRT axis regulates inflammatory response in loosening total hip replacement via modulating NF-κB signaling pathway.
Zhang Y, Zhu Q, Fang Q, Yin D, Duan Y, Xue G, Ma N, Cai Y, He M
Injury 2022 Jun;53(6):1829-1836
Injury 2022 Jun;53(6):1829-1836
Detection of netrin-1 as a novel biomarker for diagnosis and chemotherapeutic monitoring of lung cancer.
Zhao Y, Song J, Ding X, Hao Y, Cao L
The Journal of international medical research 2022 Jun;50(6):3000605221105364
The Journal of international medical research 2022 Jun;50(6):3000605221105364
MCTS1 promotes laryngeal squamous cell carcinoma cell growth via enhancing LARP7 stability.
Yang M, Ma B, Liu X
Clinical and experimental pharmacology & physiology 2022 Jun;49(6):652-660
Clinical and experimental pharmacology & physiology 2022 Jun;49(6):652-660
Serine 727 phosphorylation is necessary to induce the STAT3-mediated transcription of LINC00184 in oesophageal squamous cell carcinoma.
Jin C, Qi H, Xu Y, Li S
Molecular and cellular biochemistry 2022 Jun;477(6):1775-1787
Molecular and cellular biochemistry 2022 Jun;477(6):1775-1787
Retracted Article: LncRNA KCNQ1OT1 Promotes Apoptosis and Oxidative Stress of Human Lens Epithelial Cells through Epigenetic Regulation of WRN.
Jiang S, Jia Y, Gao Z
Current eye research 2022 Jun;47(6):I-X
Current eye research 2022 Jun;47(6):I-X
Protection of CAPE-pNO(2) Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro.
Wan Q, Zhang L, Zhou Q, Han Y, Li Z, Li B
Inflammation 2022 Jun;45(3):1039-1058
Inflammation 2022 Jun;45(3):1039-1058
Identification of HMGCR as the anticancer target of physapubenolide against melanoma cells by in silico target prediction.
Wang HY, Yu P, Chen XS, Wei H, Cao SJ, Zhang M, Zhang Y, Tao YG, Cao DS, Qiu F, Cheng Y
Acta pharmacologica Sinica 2022 Jun;43(6):1594-1604
Acta pharmacologica Sinica 2022 Jun;43(6):1594-1604
Inhibition of Fatty Acid Translocase (FAT/CD36) Palmitoylation Enhances Hepatic Fatty Acid β-Oxidation by Increasing Its Localization to Mitochondria and Interaction with Long-Chain Acyl-CoA Synthetase 1.
Zeng S, Wu F, Chen M, Li Y, You M, Zhang Y, Yang P, Wei L, Ruan XZ, Zhao L, Chen Y
Antioxidants & redox signaling 2022 Jun;36(16-18):1081-1100
Antioxidants & redox signaling 2022 Jun;36(16-18):1081-1100
LncRNA SENCR overexpression attenuated the proliferation, migration and phenotypic switching of vascular smooth muscle cells in aortic dissection via the miR-206/myocardin axis.
Song Y, Wang T, Mu C, Gui W, Deng Y, Ma R
Nutrition, metabolism, and cardiovascular diseases : NMCD 2022 Jun;32(6):1560-1570
Nutrition, metabolism, and cardiovascular diseases : NMCD 2022 Jun;32(6):1560-1570
DDX47 promotes cell proliferation and migration in lung adenocarcinoma.
Chen Y, Zeng L, Wang W, Yuan J, Sun R, Yang S
Pathology, research and practice 2022 Jun;234:153921
Pathology, research and practice 2022 Jun;234:153921
Amelioration of DSS-Induced Acute Colitis in Mice by Recombinant Monomeric Human Interleukin-22.
Kim S, Hong EH, Lee CK, Ryu Y, Jeong H, Heo S, Lee JJ, Ko HJ
Immune network 2022 Jun;22(3):e26
Immune network 2022 Jun;22(3):e26
Gli(ko) BMSC: A potential strategy of treatment for renal fibrosis.
Shi L, Gao X, Bi Y, Li M, Sun H, Tian X, Bi W
Regenerative therapy 2022 Jun;20:157-164
Regenerative therapy 2022 Jun;20:157-164
In situ forming and biocompatible hyaluronic acid hydrogel with reactive oxygen species-scavenging activity to improve traumatic brain injury repair by suppressing oxidative stress and neuroinflammation.
Zhang D, Ren Y, He Y, Chang R, Guo S, Ma S, Guan F, Yao M
Materials today. Bio 2022 Jun;15:100278
Materials today. Bio 2022 Jun;15:100278
Long noncoding RNA lnc-H2AFV-1 promotes cell growth by regulating aberrant m6A RNA modification in head and neck squamous cell carcinoma.
Chen X, Liu Y, Sun D, Sun R, Wang X, Li M, Song N, Ying J, Guo T, Jiang Y
Cancer science 2022 Jun;113(6):2071-2084
Cancer science 2022 Jun;113(6):2071-2084
Exosomal circGSE1 promotes immune escape of hepatocellular carcinoma by inducing the expansion of regulatory T cells.
Huang M, Huang X, Huang N
Cancer science 2022 Jun;113(6):1968-1983
Cancer science 2022 Jun;113(6):1968-1983
α(1) -Adrenoceptors activate the NLRP3 inflammasome through downregulation of Kir2.1 in cardiac inflammation.
Chen L, Wang W, Peng X, Liu L, Zhang A, Li X, Ma K, Wang L
Experimental physiology 2022 Jun;107(6):589-600
Experimental physiology 2022 Jun;107(6):589-600
Proteomic and functional analyses of the periodic membrane skeleton in neurons.
Zhou R, Han B, Nowak R, Lu Y, Heller E, Xia C, Chishti AH, Fowler VM, Zhuang X
Nature communications 2022 Jun 9;13(1):3196
Nature communications 2022 Jun 9;13(1):3196
Neonatal gene therapy achieves sustained disease rescue of maple syrup urine disease in mice.
Pontoizeau C, Simon-Sola M, Gaborit C, Nguyen V, Rotaru I, Tual N, Colella P, Girard M, Biferi MG, Arnoux JB, Rötig A, Ottolenghi C, de Lonlay P, Mingozzi F, Cavazzana M, Schiff M
Nature communications 2022 Jun 7;13(1):3278
Nature communications 2022 Jun 7;13(1):3278
Systematic analyses identify the anti-fibrotic role of lncRNA TP53TG1 in IPF.
Sun J, Guo Y, Chen T, Jin T, Ma L, Ai L, Guo J, Niu Z, Yang R, Wang Q, Yu X, Gao H, Zhang Y, Su W, Song X, Ji W, Zhang Q, Huang M, Fan X, Du Z, Liang H
Cell death & disease 2022 Jun 4;13(6):525
Cell death & disease 2022 Jun 4;13(6):525
mascRNA promotes macrophage apoptosis, inhibits osteoclast differentiation and attenuates disease progression in a murine model of arthritis.
Wang X, Sun T, Mao X
Biochemical and biophysical research communications 2022 Jun 30;611:151-157
Biochemical and biophysical research communications 2022 Jun 30;611:151-157
Facilitating Mitophagy via Pink1/Parkin2 Signaling Is Essential for the Neuroprotective Effect of β-Caryophyllene against CIR-Induced Neuronal Injury.
Rao J, Wu Y, Fan X, Yang S, Jiang L, Dong Z, Chen S
Brain sciences 2022 Jun 30;12(7)
Brain sciences 2022 Jun 30;12(7)
EPLINβ Is Involved in the Assembly of Cadherin-catenin Complexes in Osteoblasts and Affects Bone Formation.
Miyazaki S, Funamoto T, Sekimoto T, Kurogi S, Ohta T, Nagai T, Tajima T, Imasaka M, Yoshinobu K, Araki K, Araki M, Choijookhuu N, Hishikawa Y, Chosa E
Acta histochemica et cytochemica 2022 Jun 29;55(3):99-110
Acta histochemica et cytochemica 2022 Jun 29;55(3):99-110
Thymoquinone upregulates IL17RD in controlling the growth and metastasis of triple negative breast cancer cells in vitro.
Khan MA, Zheng M, Fu J, Tania M, Li J, Fu J
BMC cancer 2022 Jun 27;22(1):707
BMC cancer 2022 Jun 27;22(1):707
A DNA damage nanoamplifier for the chemotherapy of triple-negative breast cancer via DNA damage induction and repair blocking.
Huang Y, Dai X, Guan Z, Liu D, Ren L, Chen M, Zeng Z, Jiang J, Luo Y, He Y, Huang M, Zhao C
International journal of pharmaceutics 2022 Jun 25;622:121897
International journal of pharmaceutics 2022 Jun 25;622:121897
Effect and mechanism of TFEB on pyroptosis in HK-2 cells induced by high glucose.
Han N, Wang Z, Luo H, Chi Y, Zhang T, Wang B, Li Y
Biochemical and biophysical research communications 2022 Jun 25;610:162-169
Biochemical and biophysical research communications 2022 Jun 25;610:162-169
Design, Synthesis, and Biological Evaluation of N14-Amino Acid-Substituted Tetrandrine Derivatives as Potential Antitumor Agents against Human Colorectal Cancer.
Wang YC, Zhang RH, Hu SC, Zhang H, Yang D, Zhang WL, Zhao YL, Cui DB, Li YJ, Pan WD, Liao SG, Zhou M
Molecules (Basel, Switzerland) 2022 Jun 23;27(13)
Molecules (Basel, Switzerland) 2022 Jun 23;27(13)
Deciphering the tumor microenvironment cell-infiltrating landscape reveals microenvironment subtypes and therapeutic potentials for nonsquamous NSCLC.
Chen H, Zhang T, Zhang Y, Wu H, Fang Z, Liu Y, Chen Y, Wang Z, Jia S, Ji X, Shang L, Du F, Liu J, Lu M, Chong W
JCI insight 2022 Jun 22;7(12)
JCI insight 2022 Jun 22;7(12)
ERK1/2 Signalling Pathway Regulates Tubulin-Binding Cofactor B Expression and Affects Astrocyte Process Formation after Acute Foetal Alcohol Exposure.
Zheng Y, Huo J, Yang M, Zhang G, Wan S, Chen X, Zhang B, Liu H
Brain sciences 2022 Jun 22;12(7)
Brain sciences 2022 Jun 22;12(7)
Isolation of five different primary cell types from a single sample of human skin.
Kabacik S, Lowe D, Cohen H, Felton S, Spitzer J, Raj K
STAR protocols 2022 Jun 17;3(2):101378
STAR protocols 2022 Jun 17;3(2):101378
FUNDC2 promotes liver tumorigenesis by inhibiting MFN1-mediated mitochondrial fusion.
Li S, Han S, Zhang Q, Zhu Y, Zhang H, Wang J, Zhao Y, Zhao J, Su L, Li L, Zhou D, Ye C, Feng XH, Liang T, Zhao B
Nature communications 2022 Jun 17;13(1):3486
Nature communications 2022 Jun 17;13(1):3486
The hsa-miR-214-3p/ATGL axis regulates aberrant lipolysis to promote acute myeloid leukemia progression via PPARα in vitro.
Li Y, Yuan S, Wu W, Zhou J, Zhang P, Li D, Zhang Y, Lou S
Biochemical and biophysical research communications 2022 Jun 11;608:73-81
Biochemical and biophysical research communications 2022 Jun 11;608:73-81
Long non-coding RNA BBOX1-AS1 exacerbates esophageal squamous cell carcinoma development by regulating HOXB7/β-catenin axis.
Sheng J, Zhou M, Wang C, Jia J, Chu J, Ju C, Wan J, He J, He F
Experimental cell research 2022 Jun 1;415(1):113117
Experimental cell research 2022 Jun 1;415(1):113117
Inhibition of HIF-1α Attenuates Silica-Induced Pulmonary Fibrosis.
Xu X, Li Y, Niu Z, Xia J, Dai K, Wang C, Yao W, Guo Y, Deng X, He J, Deng M, Si H, Hao C
International journal of environmental research and public health 2022 Jun 1;19(11)
International journal of environmental research and public health 2022 Jun 1;19(11)
Protective effect of active components of Eucommia ulmoides leaves on gastric ulcers in rats: Involvement of the PI3K/Akt/NF-κB pathway.
Gong M, Li Q, Guo H, Cui B, Liu Y, Wang P, Zhu H, Liu X, Dai L, Wang Z
Journal of food science 2022 Jul;87(7):3207-3222
Journal of food science 2022 Jul;87(7):3207-3222
Methylation-mediated expression of SPARC is correlated with tumor progression and poor prognosis of breast cancer.
Li XL, Li JL, Qiu DJ, Ma L
Neoplasma 2022 Jul;69(4):794-806
Neoplasma 2022 Jul;69(4):794-806
LncRNA BIRF Promotes Brain Ischemic Tolerance Induced By Cerebral Ischemic Preconditioning Through Upregulating GLT-1 via Sponging miR-330-5p.
Li S, Zhang L, Lin J, Su A, Liu X, Zhang J, Xian X, Hu Y, Li W, Sun S, Zhang M
Molecular neurobiology 2022 Jul;59(7):3996-4014
Molecular neurobiology 2022 Jul;59(7):3996-4014
Circ_0076305 facilitates prostate cancer development via sponging miR-411-5p and regulating PGK1.
Ding X, Sun J, Zhang X
Andrologia 2022 Jul;54(6):e14406
Andrologia 2022 Jul;54(6):e14406
MG53 protein rejuvenates hUC-MSCs and facilitates their therapeutic effects in AD mice by activating Nrf2 signaling pathway.
Ma S, Zhou X, Wang Y, Li Z, Wang Y, Shi J, Guan F
Redox biology 2022 Jul;53:102325
Redox biology 2022 Jul;53:102325
The combination of decitabine and aspirin inhibits tumor growth and metastasis in non-small cell lung cancer.
Xu M, Song B, Yang X, Li N
The Journal of international medical research 2022 Jul;50(7):3000605221112024
The Journal of international medical research 2022 Jul;50(7):3000605221112024
Long Non-coding RNA ANRIL Downregulation Alleviates Neuroinflammation in an Ischemia Stroke Model via Modulation of the miR-671-5p/NF-κB Pathway.
Deng L, Jiang J, Chen S, Lin X, Zuo T, Hu Q, Wu Y, Fan X, Dong Z
Neurochemical research 2022 Jul;47(7):2002-2015
Neurochemical research 2022 Jul;47(7):2002-2015
Rosa centifolia petal extract induces endothelium-dependent and endothelium-independent vasorelaxation in rat aorta and prevents accumulation of inflammatory factors in human umbilical vein endothelial cells.
Kaneda H, Hori M, Shinomiya H, Nakajima A, Yamazaki S, Sasaki N, Sato T, Kaneda T
Journal of food biochemistry 2022 Jul;46(7):e14148
Journal of food biochemistry 2022 Jul;46(7):e14148
Gamma-oryzanol protects human liver cell (L02) from hydrogen peroxide-induced oxidative damage through regulation of the MAPK/Nrf2 signaling pathways.
Ma Y, Xiang S, Jiang W, Kong L, Tan Z, Liang Z, Yuan Z, Yi J, Zhu L
Journal of food biochemistry 2022 Jul;46(7):e14118
Journal of food biochemistry 2022 Jul;46(7):e14118
The involvement of TRPM2 on the MPP(+)-induced oxidative neurotoxicity and apoptosis in hippocampal neurons from neonatal mice: protective role of resveratrol.
Yildizhan K, Çinar R, Naziroğlu M
Neurological research 2022 Jul;44(7):636-644
Neurological research 2022 Jul;44(7):636-644
Downregulation of HINFP induces senescence-associated secretory phenotype to promote metastasis in a non-cell-autonomous manner in bladder cancer.
Zheng X, Liu Z, Zhong J, Zhou L, Chen J, Zheng L, Li Z, Zhang R, Pan J, Wu Y, Liu Z, Kang T
Oncogene 2022 Jul;41(28):3587-3598
Oncogene 2022 Jul;41(28):3587-3598
SPATA33 affects the formation of cell adhesion complex by interacting with CTNNA3 in TM4 cells.
Zhang Y
Cell and tissue research 2022 Jul;389(1):145-157
Cell and tissue research 2022 Jul;389(1):145-157
Indole-3-propionic acid alleviates ischemic brain injury in a mouse middle cerebral artery occlusion model.
Xie Y, Zou X, Han J, Zhang Z, Feng Z, Ouyang Q, Hua S, Liu Z, Li C, Cai Y, Zou Y, Tang Y, Jiang X
Experimental neurology 2022 Jul;353:114081
Experimental neurology 2022 Jul;353:114081
Mitochondrial and glucose metabolic dysfunctions in granulosa cells induce impaired oocytes of polycystic ovary syndrome through Sirtuin 3.
Zhang Q, Ren J, Wang F, Pan M, Cui L, Li M, Qu F
Free radical biology & medicine 2022 Jul;187:1-16
Free radical biology & medicine 2022 Jul;187:1-16
The BDNF-TrkB signaling pathway in the rostral anterior cingulate cortex is involved in the development of pain aversion in rats with bone cancer via NR2B and ERK-CREB signaling.
Li J, Wang X, Wang H, Wang R, Guo Y, Xu L, Zhang G, Wu J, Wang G
Brain research bulletin 2022 Jul;185:18-27
Brain research bulletin 2022 Jul;185:18-27
A specific EMC subunit supports Dengue virus infection by promoting virus membrane fusion essential for cytosolic genome delivery.
Bagchi P, Speckhart K, Kennedy A, Tai AW, Tsai B
PLoS pathogens 2022 Jul;18(7):e1010717
PLoS pathogens 2022 Jul;18(7):e1010717
Parkin-mediated mitophagy protects against TNF-α-induced stress in bone marrow mesenchymal stem cells.
Fan P, Yu XY, Chen CH, Gao JW, Xu YZ, Xie XH, Wang YT
Experimental gerontology 2022 Jul;164:111829
Experimental gerontology 2022 Jul;164:111829
Paeoniflorin-6'-o-benzene sulfonate ameliorates the progression of adjuvant-induced arthritis by inhibiting the interaction between Ahr and GRK2 of fibroblast-like synoviocytes.
Zhang BJ, Wang YY, Jia CY, Li SS, Wang XW, Xu Y, Chen AY, Xu HP, Wang C, Yang ZY, Wei W, Chang Y
International immunopharmacology 2022 Jul;108:108678
International immunopharmacology 2022 Jul;108:108678
Acetyl-L-carnitine improves erectile function in bilateral cavernous nerve injury rats via promoting cavernous nerve regeneration.
Wang J, Song J, Song G, Feng Y, Pan J, Yang X, Xin Z, Hu P, Sun T, Liu K, Xu W, Wang T, Wang S, Liu J, Ruan Y
Andrology 2022 Jul;10(5):984-996
Andrology 2022 Jul;10(5):984-996
LGALS3BP in Microglia Promotes Retinal Angiogenesis Through PI3K/AKT Pathway During Hypoxia.
Zhao C, Liu Y, Meng J, Wang X, Liu X, Li W, Zhou Q, Xiang J, Li N, Hou S
Investigative ophthalmology & visual science 2022 Jul 8;63(8):25
Investigative ophthalmology & visual science 2022 Jul 8;63(8):25
Identification of PDCD2 as a Candidate Target of Andrographolide That Arrests the Tumor Cell Cycle by Human Proteome-Scale Screening.
Wang L, Li C, Chen P, Liu C, Cui Z, Deng S, Yang H
ACS pharmacology & translational science 2022 Jul 8;5(7):479-490
ACS pharmacology & translational science 2022 Jul 8;5(7):479-490
KDM4C Contributes to Trophoblast-like Stem Cell Conversion from Porcine-Induced Pluripotent Stem Cells (piPSCs) via Regulating CDX2.
Yu S, Shen Q, Zhang R, Wu X, Zhang J, Zhao W, Wu X, Li N, Peng S, Zhang S, Yang F, Hua J
International journal of molecular sciences 2022 Jul 8;23(14)
International journal of molecular sciences 2022 Jul 8;23(14)
Stabilization of SAMHD1 by NONO is crucial for Ara-C resistance in AML.
Zhang F, Sun J, Tang X, Liang Y, Jiao Q, Yu B, Dai Z, Yuan X, Li J, Yan J, Zhang Z, Fan S, Wang M, Hu H, Zhang C, Lv XB
Cell death & disease 2022 Jul 8;13(7):590
Cell death & disease 2022 Jul 8;13(7):590
Mitochondrial fission induces immunoescape in solid tumors through decreasing MHC-I surface expression.
Lei X, Lin H, Wang J, Ou Z, Ruan Y, Sadagopan A, Chen W, Xie S, Chen B, Li Q, Wang J, Lin H, Zhu X, Yuan X, Tian T, Lv X, Fu S, Zhu X, Zhou J, Pan G, Xia X, Tannous BA, Ferrone S, Fan S, Li J
Nature communications 2022 Jul 6;13(1):3882
Nature communications 2022 Jul 6;13(1):3882
Cyclosporin A up-regulated thromboxane A(2) receptor through activation of MAPK and NF-κB pathways in rat mesenteric artery.
Wang C, Han L, Wang T, Wang Y, Liu J, Wang B, Xu CB
European journal of pharmacology 2022 Jul 5;926:175034
European journal of pharmacology 2022 Jul 5;926:175034
Sestrin2 remedies podocyte injury via orchestrating TSP-1/TGF-β1/Smad3 axis in diabetic kidney disease.
Song S, Shi C, Bian Y, Yang Z, Mu L, Wu H, Duan H, Shi Y
Cell death & disease 2022 Jul 30;13(7):663
Cell death & disease 2022 Jul 30;13(7):663
Dysregulation of SIRT3 SUMOylation Confers AML Chemoresistance via Controlling HES1-Dependent Fatty Acid Oxidation.
Zhang Y, Shen Y, Wei W, Wang W, Jiang D, Ren Y, Peng Z, Fan Q, Cheng J, Ma J
International journal of molecular sciences 2022 Jul 27;23(15)
International journal of molecular sciences 2022 Jul 27;23(15)
Severe inflammation in new-borns induces long-term cognitive impairment by activation of IL-1β/KCC2 signaling during early development.
Zhang D, Yang Y, Yang Y, Liu J, Zhu T, Huang H, Zhou C
BMC medicine 2022 Jul 27;20(1):235
BMC medicine 2022 Jul 27;20(1):235
DSF/Cu induces antitumor effect against diffuse large B-cell lymphoma through suppressing NF-κB/BCL6 pathways.
Zhu Y, Lei C, Jiang Q, Yu Q, Qiu L
Cancer cell international 2022 Jul 26;22(1):236
Cancer cell international 2022 Jul 26;22(1):236
Mitochondria-Targeting Polymer Micelle of Dichloroacetate Induced Pyroptosis to Enhance Osteosarcoma Immunotherapy.
Jin J, Yuan P, Yu W, Lin J, Xu A, Xu X, Lou J, Yu T, Qian C, Liu B, Song J, Li L, Piao Y, Xie T, Shen Y, Tao H, Tang J
ACS nano 2022 Jul 26;16(7):10327-10340
ACS nano 2022 Jul 26;16(7):10327-10340
Muscone and (+)-Borneol Cooperatively Strengthen CREB Induction of Claudin 5 in IL-1β-Induced Endothelium Injury.
Li YC, Li Y, Zhang YN, Zhao Q, Zhang PL, Sun MR, Liu BL, Yang H, Li P
Antioxidants (Basel, Switzerland) 2022 Jul 26;11(8)
Antioxidants (Basel, Switzerland) 2022 Jul 26;11(8)
miR-335-5p regulates the proliferation, migration and phenotypic switching of vascular smooth muscle cells in aortic dissection by directly regulating SP1.
Ma R, Zhang D, Song Y, Kong J, Mu C, Shen P, Gui W
Acta biochimica et biophysica Sinica 2022 Jul 25;54(7):961-973
Acta biochimica et biophysica Sinica 2022 Jul 25;54(7):961-973
Nintedanib Inhibits Endothelial Mesenchymal Transition in Bleomycin-Induced Pulmonary Fibrosis via Focal Adhesion Kinase Activity Reduction.
Yu WK, Chen WC, Su VY, Shen HC, Wu HH, Chen H, Yang KY
International journal of molecular sciences 2022 Jul 25;23(15)
International journal of molecular sciences 2022 Jul 25;23(15)
The BDNF-TrkB-CREB Signalling Pathway Is Involved in Bisphenol S-Induced Neurotoxicity in Male Mice by Regulating Methylation.
Li YZ, Wu ZY, Zhu BQ, Wang YX, Kan YQ, Zeng HC
Toxics 2022 Jul 23;10(8)
Toxics 2022 Jul 23;10(8)
CTNND1 variants cause familial exudative vitreoretinopathy through the Wnt/cadherin axis.
Yang M, Li S, Huang L, Zhao R, Dai E, Jiang X, He Y, Lu J, Peng L, Liu W, Zhang Z, Jiang D, Zhang Y, Jiang Z, Yang Y, Zhao P, Zhu X, Ding X, Yang Z
JCI insight 2022 Jul 22;7(14)
JCI insight 2022 Jul 22;7(14)
Ventilator-induced lung injury results in oxidative stress response and mitochondrial swelling in a mouse model.
Joelsson JP, Asbjarnarson A, Sigurdsson S, Kricker J, Valdimarsdottir B, Thorarinsdottir H, Starradottir E, Gudjonsson T, Ingthorsson S, Karason S
Laboratory animal research 2022 Jul 22;38(1):23
Laboratory animal research 2022 Jul 22;38(1):23
Mitotic SENP3 activation couples with cGAS signaling in tumor cells to stimulate anti-tumor immunity.
Hu G, Chen Y, Yang X, Wang Y, He J, Wang T, Fan Q, Deng L, Tu J, Tan H, Cheng J
Cell death & disease 2022 Jul 22;13(7):640
Cell death & disease 2022 Jul 22;13(7):640
Salidroside Ameliorates Radiation Damage by Reducing Mitochondrial Oxidative Stress in the Submandibular Gland.
Sun YM, Wang XY, Zhou XR, Zhang C, Liu KJ, Zhang FY, Xiang B
Antioxidants (Basel, Switzerland) 2022 Jul 21;11(7)
Antioxidants (Basel, Switzerland) 2022 Jul 21;11(7)
Ssc-MiR-21-5p and Ssc-MiR-615 Regulates the Proliferation and Apoptosis of Leydig Cells by Targeting SOX5.
Tang Q, Zhang Y, Yue L, Ren H, Pan C
Cells 2022 Jul 21;11(14)
Cells 2022 Jul 21;11(14)
Self-Assembly of a Multifunction DNA Tetrahedron for Effective Delivery of Aptamer PL1 and Pcsk9 siRNA Potentiate Immune Checkpoint Therapy for Colorectal Cancer.
Guo W, Gao H, Li H, Ge S, Zhang F, Wang L, Shi H, Han A
ACS applied materials & interfaces 2022 Jul 20;14(28):31634-31644
ACS applied materials & interfaces 2022 Jul 20;14(28):31634-31644
Spiropachysine A suppresses hepatocellular carcinoma proliferation by inducing methuosis in vitro and in vivo.
Fang Y, Zhong T, Yang L, Luo F, Li Q, Wang D, Li Q, Fan Y, Yang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul 20;102:154151
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul 20;102:154151
P2X7R/NLRP3 signaling pathway-mediated pyroptosis and neuroinflammation contributed to cognitive impairment in a mouse model of migraine.
Wang Y, Shan Z, Zhang L, Fan S, Zhou Y, Hu L, Wang Y, Li W, Xiao Z
The journal of headache and pain 2022 Jul 2;23(1):75
The journal of headache and pain 2022 Jul 2;23(1):75
Self-construction of actin networks through phase separation-induced abLIM1 condensates.
Yang S, Liu C, Guo Y, Li G, Li D, Yan X, Zhu X
Proceedings of the National Academy of Sciences of the United States of America 2022 Jul 19;119(29):e2122420119
Proceedings of the National Academy of Sciences of the United States of America 2022 Jul 19;119(29):e2122420119
TTK Protein Kinase promotes temozolomide resistance through inducing autophagy in glioblastoma.
Yu J, Gao G, Wei X, Wang Y
BMC cancer 2022 Jul 18;22(1):786
BMC cancer 2022 Jul 18;22(1):786
High glucose and palmitic acid induces neuronal senescence by NRSF/REST elevation and the subsequent mTOR-related autophagy suppression.
Xue WJ, He CF, Zhou RY, Xu XD, Xiang LX, Wang JT, Wang XR, Zhou HG, Guo JC
Molecular brain 2022 Jul 18;15(1):61
Molecular brain 2022 Jul 18;15(1):61
Chitosan Oligosaccharide Attenuates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction through Suppressing the Inflammatory Response and Oxidative Stress in Mice.
Tao W, Wang G, Pei X, Sun W, Wang M
Antioxidants (Basel, Switzerland) 2022 Jul 17;11(7)
Antioxidants (Basel, Switzerland) 2022 Jul 17;11(7)
Protective role of small extracellular vesicles derived from HUVECs treated with AGEs in diabetic vascular calcification.
Guo B, Shan SK, Xu F, Lin X, Li FX, Wang Y, Xu QS, Zheng MH, Lei LM, Li CC, Zhou ZA, Ullah MHE, Wu F, Liao XB, Yuan LQ
Journal of nanobiotechnology 2022 Jul 16;20(1):334
Journal of nanobiotechnology 2022 Jul 16;20(1):334
Adrenomedullin is an Important Pathological Mediator in Progression of Chronic Neuropathic Pain.
Wang C, Xue Y, Lu Q, Shi Y, Tang W, Wang D
Frontiers in bioscience (Landmark edition) 2022 Jul 13;27(7):220
Frontiers in bioscience (Landmark edition) 2022 Jul 13;27(7):220
Bile Duct Ligation Impairs Function and Expression of Mrp1 at Rat Blood-Retinal Barrier via Bilirubin-Induced P38 MAPK Pathway Activations.
Li P, Yang Y, Lin Z, Hong S, Jiang L, Zhou H, Yang L, Zhu L, Liu X, Liu L
International journal of molecular sciences 2022 Jul 11;23(14)
International journal of molecular sciences 2022 Jul 11;23(14)
Mitochondrial PKM2 deacetylation by procyanidin B2-induced SIRT3 upregulation alleviates lung ischemia/reperfusion injury.
Zhao J, Wang G, Han K, Wang Y, Wang L, Gao J, Zhao S, Wang G, Chen S, Luo A, Wu J, Wang G
Cell death & disease 2022 Jul 11;13(7):594
Cell death & disease 2022 Jul 11;13(7):594
TFRC upregulation promotes ferroptosis in CVB3 infection via nucleus recruitment of Sp1.
Yi L, Hu Y, Wu Z, Li Y, Kong M, Kang Z, Zuoyuan B, Yang Z
Cell death & disease 2022 Jul 11;13(7):592
Cell death & disease 2022 Jul 11;13(7):592
Effects of bamboo leaf extract intervention on the growth performance, antioxidant capacity, and hepatic apoptosis in suckling piglets.
Yu G, Ji S, Yun Y, Cheng K, Zhang H, Jia P, Wang T, Zhang L
Journal of animal science 2022 Jul 1;100(7)
Journal of animal science 2022 Jul 1;100(7)
A novel regulatory mechanism of geniposide for improving glucose homeostasis mediated by circulating RBP4.
Liu J, Song C, Nie C, Sun Y, Wang Y, Xue L, Fan M, Qian H, Wang L, Li Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153862
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153862
Protocatechuic aldehyde prevents ischemic injury by attenuating brain microvascular endothelial cell pyroptosis via lncRNA Xist.
Guo Y, Yang JH, He Y, Zhou HF, Wang Y, Ding ZS, Jin B, Wan HT
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;94:153849
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;94:153849
Hydrogen sulphide attenuates neuronal apoptosis of substantia nigra by re-establishing autophagic flux via promoting leptin signalling in a 6-hydroxydopamine rat model of Parkinson's disease.
Jiang W, Zou W, Hu M, Tian Q, Xiao F, Li M, Zhang P, Chen YJ, Jiang JM
Clinical and experimental pharmacology & physiology 2022 Jan;49(1):122-133
Clinical and experimental pharmacology & physiology 2022 Jan;49(1):122-133
Dihydroartemisinin attenuates osteoclast formation and bone resorption via inhibiting the NF‑κB, MAPK and NFATc1 signaling pathways and alleviates osteoarthritis.
Ding D, Yan J, Feng G, Zhou Y, Ma L, Jin Q
International journal of molecular medicine 2022 Jan;49(1)
International journal of molecular medicine 2022 Jan;49(1)
DR1 activation promotes vascular smooth muscle cell apoptosis via up-regulation of CSE/H(2) S pathway in diabetic mice.
Wen X, Xi Y, Zhang Y, Jiao L, Shi S, Bai S, Sun F, Chang G, Wu R, Hao J, Li H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jan;36(1):e22070
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jan;36(1):e22070
Corilagin induces apoptosis and inhibits autophagy of HL‑60 cells by regulating miR‑451/HMGB1 axis.
Jia S, He D, Liang X, Cheng P, Liu J, Chen M, Wang C, Zhang H, Meng C
Molecular medicine reports 2022 Jan;25(1)
Molecular medicine reports 2022 Jan;25(1)
Identification of a novel native peptide derived from 60S ribosomal protein L23a that translationally regulates p53 to reduce myocardial ischemia-reperfusion.
Yin A, Feng M, Zhang L, Cheng Z, Li Y, Qian L
Pharmacological research 2022 Jan;175:105988
Pharmacological research 2022 Jan;175:105988
Jujuboside A ameliorates high fat diet and streptozotocin induced diabetic nephropathy via suppressing oxidative stress, apoptosis, and enhancing autophagy.
Zhong Y, Luo R, Liu Q, Zhu J, Lei M, Liang X, Wang X, Peng X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jan;159:112697
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jan;159:112697
Adaptation to partial urethral obstruction in healthy aging LOU rats and the role of nerve growth factor signaling pathway in the bladder.
Mossa A, Cammisotto PG, Velasquez-Flores M, Campeau L
Experimental gerontology 2022 Jan;157:111625
Experimental gerontology 2022 Jan;157:111625
Overexpression of sFlt-1 represses ox-LDL-induced injury of HUVECs by activating autophagy via PI3K/AKT/mTOR pathway.
Zhou YH, Tang YZ, Guo LY, Zheng LL, Zhang D, Yang CY, Wang W
Microvascular research 2022 Jan;139:104252
Microvascular research 2022 Jan;139:104252
Dihydroartemisinin represses oral squamous cell carcinoma progression through downregulating mitochondrial calcium uniporter.
Zheng S, Wu R, Deng Y, Zhang Q
Bioengineered 2022 Jan;13(1):227-241
Bioengineered 2022 Jan;13(1):227-241
Drp1 knockdown represses apoptosis of rat retinal endothelial cells by inhibiting mitophagy.
Wu H, Li G, Chen W, Luo W, Yang Z, You Z, Zou Y
Acta histochemica 2022 Jan;124(1):151837
Acta histochemica 2022 Jan;124(1):151837
Inhibition of CDK1 attenuates neuronal apoptosis and autophagy and confers neuroprotection after chronic spinal cord injury in vivo.
Nie BX, Zhao G, Yuan XF, Yu LX, Zhang J, Yuan Y, Liu Y, Hu J, Song E, Zhou YC, Shu J
Journal of chemical neuroanatomy 2022 Jan;119:102053
Journal of chemical neuroanatomy 2022 Jan;119:102053
An in vitro senescence model of gingival epithelial cell induced by hydrogen peroxide treatment.
Giri S, Takada A, Paudel D, Yoshida K, Furukawa M, Kuramitsu Y, Matsushita K, Abiko Y, Furuichi Y
Odontology 2022 Jan;110(1):44-53
Odontology 2022 Jan;110(1):44-53
Inhibition of the proliferation, invasion, migration, and epithelial-mesenchymal transition of prostate cancer cells through the action of ATP1A2 on the TGF-β/Smad pathway.
Zhang B, Zhu Z, Zhang X, Li F, Ding A
Translational andrology and urology 2022 Jan;11(1):53-66
Translational andrology and urology 2022 Jan;11(1):53-66
Antitumor and Antibacterial Efficacy of Gallium Nanoparticles Coated by Ellagic Acid.
El-Sonbaty SM, Moawed FS, Kandil EI, M Tamamm A
Dose-response : a publication of International Hormesis Society 2022 Jan-Mar;20(1):15593258211068998
Dose-response : a publication of International Hormesis Society 2022 Jan-Mar;20(1):15593258211068998
Molecular imaging and treatment of PSMA-positive prostate cancer with (99m)Tc radiolabeled aptamer-siRNA chimeras.
Jiao Y, Xu P, Luan S, Wang X, Gao Y, Zhao C, Fu P
Nuclear medicine and biology 2022 Jan-Feb;104-105:28-37
Nuclear medicine and biology 2022 Jan-Feb;104-105:28-37
Gestational bisphenol A exposure impairs hepatic lipid metabolism by altering mTOR/CRTC2/SREBP1 in male rat offspring.
Yang Q, Mao Y, Wang J, Yu H, Zhang X, Pei X, Duan Z, Xiao C, Ma M
Human & experimental toxicology 2022 Jan-Dec;41:9603271221129852
Human & experimental toxicology 2022 Jan-Dec;41:9603271221129852
Effects of butein on human osteosarcoma cell proliferation, apoptosis, and autophagy through oxidative stress.
Zhang P, Zhang J, Quan H, Chen P, Wang J, Liang Y
Human & experimental toxicology 2022 Jan-Dec;41:9603271221074346
Human & experimental toxicology 2022 Jan-Dec;41:9603271221074346
Evodiamine suppresses the progression of non-small cell lung carcinoma via endoplasmic reticulum stress-mediated apoptosis pathway in vivo and in vitro.
Li Y, Wang Y, Wang X, Jin L, Yang L, Zhu J, Wang H, Zheng F, Cui H, Li X, Jia Y
International journal of immunopathology and pharmacology 2022 Jan-Dec;36:3946320221086079
International journal of immunopathology and pharmacology 2022 Jan-Dec;36:3946320221086079
Effects of Low-Intensity Pulsed Ultrasound on the Migration and Homing of Human Amnion-Derived Mesenchymal Stem Cells to Ovaries in Rats With Premature Ovarian Insufficiency.
Ling L, Hou J, Wang Y, Shu H, Huang Y
Cell transplantation 2022 Jan-Dec;31:9636897221129171
Cell transplantation 2022 Jan-Dec;31:9636897221129171
The role of regulatory T cells on the activation of astrocytes in the brain of high-fat diet mice following lead exposure.
Wu L, Li S, Li C, He B, Lv L, Wang J, Wang J, Wang W, Zhang Y
Chemico-biological interactions 2022 Jan 5;351:109740
Chemico-biological interactions 2022 Jan 5;351:109740
Circular RNA circCCDC85A inhibits breast cancer progression via acting as a miR-550a-5p sponge to enhance MOB1A expression.
Meng L, Chang S, Sang Y, Ding P, Wang L, Nan X, Xu R, Liu F, Gu L, Zheng Y, Li Z, Sang M
Breast cancer research : BCR 2022 Jan 4;24(1):1
Breast cancer research : BCR 2022 Jan 4;24(1):1
Ceria nanoparticles ameliorate renal fibrosis by modulating the balance between oxidative phosphorylation and aerobic glycolysis.
Wang M, Zeng F, Ning F, Wang Y, Zhou S, He J, Li C, Wang C, Sun X, Zhang D, Xiao J, Hu P, Reilly S, Xin H, Xu X, Zhang X
Journal of nanobiotechnology 2022 Jan 4;20(1):3
Journal of nanobiotechnology 2022 Jan 4;20(1):3
Increased expression of osteopontin in subchondral bone promotes bone turnover and remodeling, and accelerates the progression of OA in a mouse model.
Lin C, Chen Z, Guo D, Zhou L, Lin S, Li C, Li S, Wang X, Lin B, Ding Y
Aging 2022 Jan 4;14(1):253-271
Aging 2022 Jan 4;14(1):253-271
A comprehensive analysis of age-related metabolomics and transcriptomics reveals metabolic alterations in rat bone marrow mesenchymal stem cells.
Yu X, Sun H, Gao X, Zhang C, Sun Y, Wang H, Zhang H, Shi Y, He X
Aging 2022 Jan 30;14(2):1014-1032
Aging 2022 Jan 30;14(2):1014-1032
Leptin relieves ischemia/reperfusion induced acute kidney injury through inhibiting apoptosis and autophagy.
Li S, Zhuang K, He Y, Deng Y, Xi J, Chen J
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 2022 Jan 28;47(1):8-17
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 2022 Jan 28;47(1):8-17
NAD(P)H: quinone oxidoreductase 1 attenuates oxidative stress and apoptosis by regulating Sirt1 in diabetic nephropathy.
Qiu D, Song S, Wang Y, Bian Y, Wu M, Wu H, Shi Y, Duan H
Journal of translational medicine 2022 Jan 28;20(1):44
Journal of translational medicine 2022 Jan 28;20(1):44
Mitigation Effects of Selenium Nanoparticles on Depression-Like Behavior Induced by Fluoride in Mice via the JAK2-STAT3 Pathway.
Yang J, Li H, Hao Z, Jing X, Zhao Y, Cheng X, Ma H, Wang J, Wang J
ACS applied materials & interfaces 2022 Jan 26;14(3):3685-3700
ACS applied materials & interfaces 2022 Jan 26;14(3):3685-3700
Structural Variability of Lipoarabinomannan Modulates Innate Immune Responses within Infected Alveolar Epithelial Cells.
Liu H, Gui X, Chen S, Fu W, Li X, Xiao T, Hou J, Jiang T
Cells 2022 Jan 21;11(3)
Cells 2022 Jan 21;11(3)
FSH inhibits autophagy and lysosomal biogenesis to regulate protein degradation in cultured goat Sertoli cells.
Xi H, Ren F, Li Y, Xian M, Wang L, Hu J
Molecular and cellular endocrinology 2022 Jan 15;540:111505
Molecular and cellular endocrinology 2022 Jan 15;540:111505
In vitro and in silico anti-osteoporosis activities and underlying mechanisms of a fructan, ABW90-1, from Achyranthes bidentate.
Li T, Hou X, Huang Y, Wang C, Chen H, Yan C
Carbohydrate polymers 2022 Jan 15;276:118730
Carbohydrate polymers 2022 Jan 15;276:118730
Exosomal circRELL1 serves as a miR-637 sponge to modulate gastric cancer progression via regulating autophagy activation.
Sang H, Zhang W, Peng L, Wei S, Zhu X, Huang K, Yang J, Chen M, Dang Y, Zhang G
Cell death & disease 2022 Jan 13;13(1):56
Cell death & disease 2022 Jan 13;13(1):56
Phosphorylation-Induced Ubiquitination and Degradation of PXR through CDK2-TRIM21 Axis.
Qin M, Xin Y, Bian Y, Yang X, Xi T, Xiong J
Cells 2022 Jan 13;11(2)
Cells 2022 Jan 13;11(2)
Xiaoyao powder improves endometrial receptivity via VEGFR-2-mediated angiogenesis through the activation of the JNK and P38 signaling pathways.
He M, Li L, Wei X, Geng D, Jiang H, Xiangxiang G, Zhang Y, Du H
Journal of ethnopharmacology 2022 Jan 10;282:114580
Journal of ethnopharmacology 2022 Jan 10;282:114580
(125)I seeds inhibit proliferation and promote apoptosis in cholangiocarcinoma cells by regulating the AGR2-mediated p38 MAPK pathway.
Zhou X, Zhang W, Dou M, Li Z, Liu Z, Li J, Tian C, Yao Y, Wang C, Li Y, Chen P, Han X, Jiao D
Cancer letters 2022 Jan 1;524:29-41
Cancer letters 2022 Jan 1;524:29-41
Eurycomanol alleviates hyperuricemia by promoting uric acid excretion and reducing purine synthesis.
Bao R, Chen Q, Li Z, Wang D, Wu Y, Liu M, Zhang Y, Wang T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153850
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153850
Isoliquiritigenin-mediated miR-23a-3p inhibition activates PGC-1α to alleviate alcoholic liver injury.
Wang L, Kong L, Xu S, Wang X, Huang K, Wang S, Wu J, Wang C, Sun H, Liu K, Meng Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153845
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153845
Activation of the NLRP3 inflammasome by RAC1 mediates a new mechanism in diabetic nephropathy.
Ying C, Zhou Z, Dai J, Wang M, Xiang J, Sun D, Zhou X
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2022 Feb;71(2):191-204
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2022 Feb;71(2):191-204
Single Treatment of Vitamin D3 Ameliorates LPS-Induced Acute Lung Injury through Changing Lung Rodentibacter abundance.
Jin A, Zhao Y, Yuan Y, Ma S, Chen J, Yang X, Lu S, Sun Q
Molecular nutrition & food research 2022 Feb;66(3):e2100952
Molecular nutrition & food research 2022 Feb;66(3):e2100952
Mesenchymal-to-epithelial transition of osteoblasts induced by Fam20c knockout.
Geng YW, Zhang Z, Jin H, Da JL, Zhang K, Wang JQ, Guo YY, Zhang B, Li Y
Genes & genomics 2022 Feb;44(2):155-164
Genes & genomics 2022 Feb;44(2):155-164
Hydrogen sulfide alleviates apoptosis and autophagy induced by beryllium sulfate in 16HBE cells.
Liu YP, Yuan XY, Li XY, Wang Y, Sun ZB, Deng WH, Lei YD, Huang L, Jiang TY, Zhang ZH
Journal of applied toxicology : JAT 2022 Feb;42(2):230-243
Journal of applied toxicology : JAT 2022 Feb;42(2):230-243
1H-NMR-based metabolomics reveals the biomarker panel and molecular mechanism of hepatocellular carcinoma progression.
Wang KX, Du GH, Qin XM, Gao L
Analytical and bioanalytical chemistry 2022 Feb;414(4):1525-1537
Analytical and bioanalytical chemistry 2022 Feb;414(4):1525-1537
Inhibition of MAT2A suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss.
Kang H, Guo Q, Dong Y, Peng R, Song K, Wang J, Liu H, Zhu M, Zhao H, Guan H, Li F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Feb;36(2):e22167
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Feb;36(2):e22167
STING-mediated inflammation contributes to Gao binge ethanol feeding model.
Wang L, You HM, Meng HW, Pan XY, Chen X, Bi YH, Zhang YF, Li JJ, Yin NN, Zhang ZW, Huang C, Li J
Journal of cellular physiology 2022 Feb;237(2):1471-1485
Journal of cellular physiology 2022 Feb;237(2):1471-1485
Cardiotoxicity of patulin was found in H9c2 cells.
Zhang B, Liang H, Huang K, Li J, Xu D, Huang C, Li Y
Toxicon : official journal of the International Society on Toxinology 2022 Feb;207:21-30
Toxicon : official journal of the International Society on Toxinology 2022 Feb;207:21-30
HMGB1 downregulation in retinal pigment epithelial cells protects against diabetic retinopathy through the autophagy-lysosome pathway.
Feng L, Liang L, Zhang S, Yang J, Yue Y, Zhang X
Autophagy 2022 Feb;18(2):320-339
Autophagy 2022 Feb;18(2):320-339
Activation of RIPK2-mediated NOD1 signaling promotes proliferation and invasion of ovarian cancer cells via NF-κB pathway.
Zhang W, Wang Y
Histochemistry and cell biology 2022 Feb;157(2):173-182
Histochemistry and cell biology 2022 Feb;157(2):173-182
Prunella vulgaris can improve the pregnancy outcomes of experimental autoimmune thyroiditis rats by inhibiting Th1/Th17 immune responses.
Zhu Q, Muyayalo KP, Xu QH, Wang J, Wang H, Liao AH
Journal of reproductive immunology 2022 Feb;149:103469
Journal of reproductive immunology 2022 Feb;149:103469
Enhancement of anti-inflammatory effect of cattle bile by fermentation and its inhibition of neuroinflammation on microglia by inhibiting NLRP3 inflammasome.
Pei Y, Cheng F, Li W, Yu Q, Ma C, Zou Y, Xu T, Liu S, Zhang S, Wang Q
Journal of bioscience and bioengineering 2022 Feb;133(2):146-154
Journal of bioscience and bioengineering 2022 Feb;133(2):146-154
Polygonum cuspidatum inhibits the growth of osteosarcoma cells via impeding Akt/ERK/EGFR signaling pathways.
Zhao J, Pan B, Zhou X, Wu C, Hao F, Zhang J, Liu L
Bioengineered 2022 Feb;13(2):2992-3006
Bioengineered 2022 Feb;13(2):2992-3006
Hyperglycemia induces miR-26-5p down-regulation to overexpress PFKFB3 and accelerate epithelial-mesenchymal transition in gastric cancer.
He X, Cheng X, Ding J, Xiong M, Chen B, Cao G
Bioengineered 2022 Feb;13(2):2902-2917
Bioengineered 2022 Feb;13(2):2902-2917
Dye-Sensitized Rare Earth Nanoparticles with Up/Down Conversion Luminescence for On-Demand Gas Therapy of Glioblastoma Guided by NIR-II Fluorescence Imaging.
Liu Z, Yun B, Han Y, Jiang Z, Zhu H, Ren F, Li Z
Advanced healthcare materials 2022 Feb;11(3):e2102042
Advanced healthcare materials 2022 Feb;11(3):e2102042
The synergistic anticancer effect of the bromodomain inhibitor OTX015 and histone deacetylase 6 inhibitor WT-161 in osteosarcoma.
Yu B, Liu L, Cai F, Peng Y, Tang X, Zeng D, Li T, Zhang F, Liang Y, Yuan X, Li J, Dai Z, Liao Q, Lv XB
Cancer cell international 2022 Feb 8;22(1):64
Cancer cell international 2022 Feb 8;22(1):64
The human FOXM1 homolog promotes basal progenitor cell proliferation and cortical folding in mouse.
Wang W, Su L, Ji F, Zhang D, Wang Y, Zhao J, Jiao RD, Zhang M, Huang E, Jiang H, Zhang J, Jiao J
EMBO reports 2022 Feb 3;23(3):e53602
EMBO reports 2022 Feb 3;23(3):e53602
Developing a Mathematical Model of Intracellular Calcium Dynamics for Evaluating Combined Anticancer Effects of Afatinib and RP4010 in Esophageal Cancer.
Chang Y, Funk M, Roy S, Stephenson E, Choi S, Kojouharov HV, Chen B, Pan Z
International journal of molecular sciences 2022 Feb 3;23(3)
International journal of molecular sciences 2022 Feb 3;23(3)
HDAC9 Contributes to Serous Ovarian Cancer Progression through Regulating Epithelial-Mesenchymal Transition.
Xu L, Wang J, Liu B, Fu J, Zhao Y, Yu S, Shen L, Yan X, Su J
Biomedicines 2022 Feb 3;10(2)
Biomedicines 2022 Feb 3;10(2)
The anti-MDR efficacy of YAN against A549/Taxol cells is associated with its inhibition on glycolysis and is further enhanced by 2-deoxy-d-glucose.
Gao M, Yang Y, Gao Y, Liu T, Guan Q, Zhou T, Shi Y, Hao M, Li Z, Zuo D, Zhang W, Wu Y
Chemico-biological interactions 2022 Feb 25;354:109843
Chemico-biological interactions 2022 Feb 25;354:109843
Carrier-free multifunctional nanomedicine for intraperitoneal disseminated ovarian cancer therapy.
Huang X, Qiu M, Wang T, Li B, Zhang S, Zhang T, Liu P, Wang Q, Qian ZR, Zhu C, Wu M, Zhao J
Journal of nanobiotechnology 2022 Feb 22;20(1):93
Journal of nanobiotechnology 2022 Feb 22;20(1):93
Ginkgo biloba leaf extract mitigates cisplatin-induced chronic renal interstitial fibrosis by inhibiting the epithelial-mesenchymal transition of renal tubular epithelial cells mediated by the Smad3/TGF-β1 and Smad3/p38 MAPK pathways.
Wei C, Zhang Y, Zhong X, Lu S, Zou X, Yang Y, Huang S, Huang Z
Chinese medicine 2022 Feb 21;17(1):25
Chinese medicine 2022 Feb 21;17(1):25
Transketolase promotes colorectal cancer metastasis through regulating AKT phosphorylation.
Li M, Zhao X, Yong H, Xu J, Qu P, Qiao S, Hou P, Li Z, Chu S, Zheng J, Bai J
Cell death & disease 2022 Feb 2;13(2):99
Cell death & disease 2022 Feb 2;13(2):99
Mitochondrial homeostasis regulates definitive endoderm differentiation of human pluripotent stem cells.
Lv J, Yi Y, Qi Y, Yan C, Jin W, Meng L, Zhang D, Jiang W
Cell death discovery 2022 Feb 17;8(1):69
Cell death discovery 2022 Feb 17;8(1):69
Preparation, Characterization, Evaluation of Neuroprotective Effect, and Related Mechanisms of Phosphatidylserine Emulsion in 5- and 12-Week Old Mice.
Liu B, Zhang N, Yang J, Sun W, Zhang R, Zheng X, Wang Z, Siebert HC, Han J
Journal of agricultural and food chemistry 2022 Feb 16;70(6):1852-1864
Journal of agricultural and food chemistry 2022 Feb 16;70(6):1852-1864
Isovitexin protects against acute liver injury by targeting PTEN, PI3K and BiP via modification of m6A.
Huang Y, Chen S, Pang L, Feng Z, Su H, Zhu W, Wei J
European journal of pharmacology 2022 Feb 15;917:174749
European journal of pharmacology 2022 Feb 15;917:174749
TiO(2) nanosheets promote the transformation of vascular smooth muscle cells into foam cells in vitro and in vivo through the up-regulation of nuclear factor kappa B subunit 2.
Li S, Yan D, Huang C, Yang F, Cao Y
Journal of hazardous materials 2022 Feb 15;424(Pt D):127704
Journal of hazardous materials 2022 Feb 15;424(Pt D):127704
Blockage of citrate export prevents TCA cycle fragmentation via Irg1 inactivation.
Li Y, Li YC, Liu XT, Zhang L, Chen YH, Zhao Q, Gao W, Liu B, Yang H, Li P
Cell reports 2022 Feb 15;38(7):110391
Cell reports 2022 Feb 15;38(7):110391
Liver fibrosis alters the molecular structures of hepatic glycogen.
Wan Y, Hu Z, Liu Q, Wang L, Sullivan MA, Gilbert RG
Carbohydrate polymers 2022 Feb 15;278:118991
Carbohydrate polymers 2022 Feb 15;278:118991
The expression of m6A enzymes in the hippocampus of diabetic cognitive impairment mice and the possible improvement of YTHDF1.
Li M, Zhong X, Zhao Z, Zeng Z, Yuan Q, Xiao X, Zu X, Liu J
Brain research 2022 Feb 15;1777:147766
Brain research 2022 Feb 15;1777:147766
African Swine Fever Virus K205R Induces ER Stress and Consequently Activates Autophagy and the NF-κB Signaling Pathway.
Wang Q, Zhou L, Wang J, Su D, Li D, Du Y, Yang G, Zhang G, Chu B
Viruses 2022 Feb 15;14(2)
Viruses 2022 Feb 15;14(2)
Ergosterol Peroxide Inhibits Porcine Epidemic Diarrhea Virus Infection in Vero Cells by Suppressing ROS Generation and p53 Activation.
Liu Y, Wang X, Wang J, Zhang J, Duan C, Wang J
Viruses 2022 Feb 15;14(2)
Viruses 2022 Feb 15;14(2)
Genetic Deletion of HLJ1 Does Not Affect Blood Coagulation in Mice.
Hsu MC, Luo WJ, Guo BC, Chen CH, Hu PA, Tsai YH, Su KY, Lee TS
International journal of molecular sciences 2022 Feb 13;23(4)
International journal of molecular sciences 2022 Feb 13;23(4)
Intake of flavonoids from Astragalus membranaceus ameliorated brain impairment in diabetic mice via modulating brain-gut axis.
Li X, Zhao T, Gu J, Wang Z, Lin J, Wang R, Duan T, Li Z, Dong R, Wang W, Hong KF, Liu Z, Huang W, Gui D, Zhou H, Xu Y
Chinese medicine 2022 Feb 12;17(1):22
Chinese medicine 2022 Feb 12;17(1):22
Sestrin2 reduces cancer stemness via Wnt/β-catenin signaling in colorectal cancer.
Wei J, Zheng X, Li W, Li X, Fu Z
Cancer cell international 2022 Feb 11;22(1):75
Cancer cell international 2022 Feb 11;22(1):75
Pt(II)-NHC Complex Induces ROS-ERS-Related DAMP Balance to Harness Immunogenic Cell Death in Hepatocellular Carcinoma.
Bian M, Fan R, Yang Z, Chen Y, Xu Z, Lu Y, Liu W
Journal of medicinal chemistry 2022 Feb 10;65(3):1848-1866
Journal of medicinal chemistry 2022 Feb 10;65(3):1848-1866
Exploring the pharmacological mechanism of calculus bovis in cerebral ischaemic stroke using a network pharmacology approach.
Du X, Li C, Zhang S, Sun C, Zhang X, Chen C, Wang X, Cheng F, Wang Q
Journal of ethnopharmacology 2022 Feb 10;284:114507
Journal of ethnopharmacology 2022 Feb 10;284:114507
Immobilization of peroxisome proliferator-activated receptor gamma and the application in screening modulators of the receptor from herbal medicine.
Hou Z, Jin Y, Li Y, Fan H, Xiao C, Li Q, Zhang Y
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2022 Feb 1;1190:123098
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2022 Feb 1;1190:123098
Effects of STAT3 Inhibitor BP-1-102 on The Proliferation, Invasiveness, Apoptosis and Neurosphere Formation of Glioma Cells in Vitro.
Zhang CC, Wu T, Guan L, Wang YJ, Yao RQ, Gao DS, Li F
Cell biochemistry and biophysics 2022 Dec;80(4):723-735
Cell biochemistry and biophysics 2022 Dec;80(4):723-735
Cystine Induced-mTORC2 Activation through Promoting Sin1 Phosphorylation to Suppress Cancer Cell Ferroptosis.
Wang G, Chen L, Qin S, Zheng Y, Xia C, Yao J, Wang P, Deng L
Molecular nutrition & food research 2022 Dec;66(23):e2200186
Molecular nutrition & food research 2022 Dec;66(23):e2200186
A plant-derived natural photosynthetic system for improving cell anabolism.
Chen P, Liu X, Gu C, Zhong P, Song N, Li M, Dai Z, Fang X, Liu Z, Zhang J, Tang R, Fan S, Lin X
Nature 2022 Dec;612(7940):546-554
Nature 2022 Dec;612(7940):546-554
Cinobufagin induces acute promyelocytic leukaemia cell apoptosis and PML-RARA degradation in a caspase-dependent manner by inhibiting the β-catenin signalling pathway.
Bian Y, Xue M, Guo X, Jiang W, Zhao Y, Zhang Z, Wang X, Hu Y, Zhang Q, Dun W, Zhang L
Pharmaceutical biology 2022 Dec;60(1):1801-1811
Pharmaceutical biology 2022 Dec;60(1):1801-1811
Antidepressant effects of total alkaloids of Fibraurea recisa on improving corticosterone-induced apoptosis of HT-22 cells and chronic unpredictable mild stress-induced depressive-like behaviour in mice.
He Z, Yu H, Wu H, Su L, Shi K, Zhao Y, Zong Y, Chen W, Du R
Pharmaceutical biology 2022 Dec;60(1):1436-1448
Pharmaceutical biology 2022 Dec;60(1):1436-1448
ChemR23 signaling ameliorates cognitive impairments in diabetic mice via dampening oxidative stress and NLRP3 inflammasome activation.
Zhang J, Liu L, Zhang Y, Yuan Y, Miao Z, Lu K, Zhang X, Ni R, Zhang H, Zhao Y, Wang X
Redox biology 2022 Dec;58:102554
Redox biology 2022 Dec;58:102554
Taurine protects R28 cells from hypoxia/re-oxygenation-induced damage via regulation of mitochondrial energy metabolism.
Lu W, Yang Y, Gao S, Wu J, Sun X
Amino acids 2022 Dec;54(12):1585-1599
Amino acids 2022 Dec;54(12):1585-1599
Holothuria Leucospilota polysaccharides alleviate hyperlipidemia via alteration of lipid metabolism and inflammation-related gene expression.
Lu S, Yuan Y, Chen F, Zheng Y, Li C, Cao J, Xia G, Liu Z, Shen X, He Y, Zhou D, Zhu K
Journal of food biochemistry 2022 Dec;46(12):e14392
Journal of food biochemistry 2022 Dec;46(12):e14392
Resveratrol inhibits the progression of premature senescence partially by regulating v-rel avian reticuloendotheliosis viral oncogene homolog A (RELA) and sirtuin 1 (SIRT1).
He S, Zhou M, Zheng H, Wang Y, Wu S, Gao Y, Chen J
Renal failure 2022 Dec;44(1):171-183
Renal failure 2022 Dec;44(1):171-183
Salidroside inhibited cerebral ischemia/reperfusion-induced oxidative stress and apoptosis via Nrf2/Trx1 signaling pathway.
Li F, Mao Q, Wang J, Zhang X, Lv X, Wu B, Yan T, Jia Y
Metabolic brain disease 2022 Dec;37(8):2965-2978
Metabolic brain disease 2022 Dec;37(8):2965-2978
Loureirin C ameliorates ischemia and reperfusion injury in rats by inhibiting the activation of the TLR4/NF-κB pathway and promoting TLR4 degradation.
Xu J, Liu J, Li Q, Mi Y, Zhou D, Wang J, Chen G, Liang D, Li N, Hou Y
Phytotherapy research : PTR 2022 Dec;36(12):4527-4541
Phytotherapy research : PTR 2022 Dec;36(12):4527-4541
A comprehensive analysis on the relationship between BDE-209 exposure and erectile dysfunction.
Zhou X, Song L, Cong R, Luan J, Zhou X, Wang Y, Yao L, Zhang X, Ren X, Zhang T, Yu M, Song N
Chemosphere 2022 Dec;308(Pt 3):136486
Chemosphere 2022 Dec;308(Pt 3):136486
CEND1 deficiency induces mitochondrial dysfunction and cognitive impairment in Alzheimer's disease.
Xie W, Guo D, Li J, Yue L, Kang Q, Chen G, Zhou T, Wang H, Zhuang K, Leng L, Li H, Chen Z, Gao W, Zhang J
Cell death and differentiation 2022 Dec;29(12):2417-2428
Cell death and differentiation 2022 Dec;29(12):2417-2428
Anti-photoaging effects of flexible nanoliposomes encapsulated Moringa oleifera Lam. isothiocyanate in UVB-induced cell damage in HaCaT cells.
Wang Y, Ouyang Q, Chang X, Yang M, He J, Tian Y, Sheng J
Drug delivery 2022 Dec;29(1):871-881
Drug delivery 2022 Dec;29(1):871-881
Sevelamer arsenite nanoparticle as a Pi-responsive drug carrier and embolic agent for chemoembolization.
Bi QC, Tang JJ, Zhao J, Lv YF, Deng ZQ, Chen H, Xu YH, Xie CS, Liang QR, Luo RG, Tang Q
Drug delivery 2022 Dec;29(1):1447-1456
Drug delivery 2022 Dec;29(1):1447-1456
Hypoxia-Inducible Factor 1α Stability Modified by Glutaredoxin-1 in Necrotizing Enterocolitis.
Zhang Y, Zhang X, Tian B, Deng Q, Guo C
The Journal of surgical research 2022 Dec;280:429-439
The Journal of surgical research 2022 Dec;280:429-439
Mild hypothermia ameliorates hepatic ischemia reperfusion injury by inducing RBM3 expression.
Xiao Q, Liu Y, Zhang X, Liu Z, Xiao J, Ye Q, Fu B
Apoptosis : an international journal on programmed cell death 2022 Dec;27(11-12):899-912
Apoptosis : an international journal on programmed cell death 2022 Dec;27(11-12):899-912
Orientin downregulating oxidative stress-mediated endoplasmic reticulum stress and mitochondrial dysfunction through AMPK/SIRT1 pathway in rat nucleus pulposus cells in vitro and attenuated intervertebral disc degeneration in vivo.
Zhang Z, Wu J, Teng C, Wang J, Yu J, Jin C, Wang L, Wu L, Lin Z, Yu Z, Lin Z
Apoptosis : an international journal on programmed cell death 2022 Dec;27(11-12):1031-1048
Apoptosis : an international journal on programmed cell death 2022 Dec;27(11-12):1031-1048
Tetrandrine overcomes drug resistance mediated by bone marrow microenvironment by regulating the expression of P-glycoprotein in acute leukemia.
Zhou X, Jin N, Chen B
Hematology (Amsterdam, Netherlands) 2022 Dec;27(1):274-279
Hematology (Amsterdam, Netherlands) 2022 Dec;27(1):274-279
SREBP2/Rab11s/GLUT1/6 network regulates proliferation and migration of glioblastoma.
Cheng C, Tu J, Hu Z, Chen Y, Wang Y, Zhang T, Zhang C, Li C, Wang Y, Niu C
Pathology, research and practice 2022 Dec;240:154176
Pathology, research and practice 2022 Dec;240:154176
Global Phosphoproteomics Unveils Kinase-Regulated Networks in Systemic Lupus Erythematosus.
Meng S, Li T, Wang T, Li D, Chen J, Li H, Cai W, Zeng Z, Liu D, Tang D, Hong X, Dai Y
Molecular & cellular proteomics : MCP 2022 Dec;21(12):100434
Molecular & cellular proteomics : MCP 2022 Dec;21(12):100434
Study on the mechanism of scutellarin's protective effect against ZEA-induced mouse ovarian granulosa cells injury.
Yi Y, Hao Z, Sun P, Fan K, Yin W, Guo J, Zheng X, Sun N, Li H
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Dec;170:113481
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Dec;170:113481
Enhancement of the functionality of attenuating acute lung injury by a microemulsion formulation with volatile oil of Angelicae Sinensis Radix and Ligusticum Chuanxiong Rhizoma encapsulated.
Zhang L, Yan Q, Zhang W, Li X, Zhang X, Du S, Hua X, Lin J, Shu G, Peng G, Tan Z, Fu H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Dec;156:113888
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Dec;156:113888
Hyperoside protects against cyclophosphamide induced ovarian damage and reduced fertility by suppressing HIF-1α/BNIP3-mediated autophagy.
Zhu F, Gao J, Zeng F, Lai Y, Ruan X, Deng G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Dec;156:113743
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Dec;156:113743
miR-141-3p affects β-catenin signaling and apoptosis by targeting Ubtd2 in rats with anorectal malformations.
Wang CY, Li SY, Xiao YX, Zhen L, Wei XG, Tang XB, Yuan ZW, Bai YZ
Annals of the New York Academy of Sciences 2022 Dec;1518(1):315-327
Annals of the New York Academy of Sciences 2022 Dec;1518(1):315-327
Bioelectric fields coordinate wound contraction and re-epithelialization process to accelerate wound healing via promoting myofibroblast transformation.
Yang J, Liu X, Wang W, Chen Y, Liu J, Zhang Z, Wu C, Jiang X, Liang Y, Zhang J
Bioelectrochemistry (Amsterdam, Netherlands) 2022 Dec;148:108247
Bioelectrochemistry (Amsterdam, Netherlands) 2022 Dec;148:108247
1,25(OH)(2)D(3) alleviates LPS-induced preeclampsia-like rats impairment in the protective effect by TLR4/NF-kB pathway.
Ma Y, Yang Y, Lv M, Zhang Y, He Q, Zhang Y, Su H, Deng X, Qian Y
Placenta 2022 Dec;130:34-41
Placenta 2022 Dec;130:34-41
Activation of RKIP Binding ASC Attenuates Neuronal Pyroptosis and Brain Injury via Caspase-1/GSDMD Signaling Pathway After Intracerebral Hemorrhage in Mice.
Gu L, Sun M, Li R, Tao Y, Luo X, Xu J, Wu X, Xie Z
Translational stroke research 2022 Dec;13(6):1037-1054
Translational stroke research 2022 Dec;13(6):1037-1054
Inhibition of glutamine transporter ASCT2 mitigates bleomycin-induced pulmonary fibrosis in mice.
Lian N, Jin H, Zhu W, Zhang C, Qi Y, Jiang M, Mao J, Lu X, Zhao F, Xi B, Qi X, Li Y
Acta histochemica 2022 Dec;124(8):151961
Acta histochemica 2022 Dec;124(8):151961
MCPIP1 alleviates inflammatory response through inducing autophagy in Aspergillus fumigatus keratitis.
Han F, Shen L, Ma H, Wang L, Guo H, Wu X
International immunopharmacology 2022 Dec;113(Pt A):109279
International immunopharmacology 2022 Dec;113(Pt A):109279
A mouse-adapted CVA6 strain exhibits neurotropism and triggers systemic manifestations in a novel murine model.
Li D, Sun T, Tao L, Ji W, Zhu P, Liang R, Zhang Y, Chen S, Yang H, Jin Y, Duan G
Emerging microbes & infections 2022 Dec;11(1):2248-2263
Emerging microbes & infections 2022 Dec;11(1):2248-2263
Probiotic-fermented Pueraria lobata (Willd.) Ohwi alleviates alcoholic liver injury by enhancing antioxidant defense and modulating gut microbiota.
Zhao W, Peng D, Li W, Chen S, Liu B, Huang P, Wu J, Du B, Li P
Journal of the science of food and agriculture 2022 Dec;102(15):6877-6888
Journal of the science of food and agriculture 2022 Dec;102(15):6877-6888
GALNT3 protects against phosphate-induced calcification in vascular smooth muscle cells by enhancing active FGF23 and inhibiting the wnt/β-catenin signaling pathway.
Guo L, Wang Y, Li S, Zhou L, Li D
Cellular signalling 2022 Dec;100:110477
Cellular signalling 2022 Dec;100:110477
MicroRNA-200c Affects Milk Fat Synthesis by Targeting PANK3 in Ovine Mammary Epithelial Cells.
Hao Z, Wang J, Luo Y, Hu J, Liu X, Li S, Li M, Shi B, Hu L, Liu Y, Zhen H
International journal of molecular sciences 2022 Dec 9;23(24)
International journal of molecular sciences 2022 Dec 9;23(24)
A Recombinant Genotype I Japanese Encephalitis Virus Expressing a Gaussia Luciferase Gene for Antiviral Drug Screening Assay and Neutralizing Antibodies Detection.
Li C, Chen X, Hu J, Jiang D, Cai D, Li Y
International journal of molecular sciences 2022 Dec 8;23(24)
International journal of molecular sciences 2022 Dec 8;23(24)
Cordycepin exhibits anti-fatigue effect via activating TIGAR/SIRT1/PGC-1α signaling pathway.
Chai X, Pan M, Wang J, Feng M, Wang Y, Zhang Q, Sun Y
Biochemical and biophysical research communications 2022 Dec 31;637:127-135
Biochemical and biophysical research communications 2022 Dec 31;637:127-135
FLI1 accelerates leukemogenesis through transcriptional regulation of pyruvate kinase-L/R and other glycolytic genes.
Sheng D, Chen B, Wang C, Xiao X, Hu A, Liu W, Kuang Y, Sample KM, Zacksenhaus E, Gajendran B, Pan W, Ben-David Y
Medical oncology (Northwood, London, England) 2022 Dec 31;40(2):69
Medical oncology (Northwood, London, England) 2022 Dec 31;40(2):69
TOP2A deficiency leads to human recurrent spontaneous abortion and growth retardation of mouse pre-implantation embryos.
Duan Y, Fu H, Huang J, Yin N, Liu L, Liu X
Molecular medicine (Cambridge, Mass.) 2022 Dec 30;28(1):165
Molecular medicine (Cambridge, Mass.) 2022 Dec 30;28(1):165
FNDC5 Promotes Adipogenic Differentiation of Primary Preadipocytes in Mashen Pigs.
Hei W, You Z, An J, Zhao T, Li J, Zhang W, Li M, Yang Y, Gao P, Cao G, Guo X, Cai C, Li B
Genes 2022 Dec 28;14(1)
Genes 2022 Dec 28;14(1)
Circadian Rhythm Disorders Aggravate Periodontitis by Modulating BMAL1.
Liu X, Cao N, Liu X, Deng Y, Xin Y, Fu R, Xin X, Hou Y, Yu W
International journal of molecular sciences 2022 Dec 26;24(1)
International journal of molecular sciences 2022 Dec 26;24(1)
Renoprotective effects of oleanolic acid and its possible mechanisms in rats with diabetic kidney disease.
Liu Y, Hu Z, Xing H, Kang L, Chen X, Liu B, Niu K
Biochemical and biophysical research communications 2022 Dec 25;636(Pt 1):1-9
Biochemical and biophysical research communications 2022 Dec 25;636(Pt 1):1-9
Cefotetan-bound human RKIP involves in Ras/Raf1/MEK/ERK signaling pathway.
Guo C, Xu H, Zhou Y, Wu Z, Jiang B, Chen H, Lin D
Acta biochimica et biophysica Sinica 2022 Dec 25;54(12):1917-1923
Acta biochimica et biophysica Sinica 2022 Dec 25;54(12):1917-1923
Low Sulfur Amino Acid, High Polyunsaturated Fatty Acid Diet Inhibits Breast Cancer Growth.
Turchi R, Tortolici F, Benvenuto M, Punziano C, De Luca A, Rufini S, Faraonio R, Bei R, Lettieri-Barbato D, Aquilano K
International journal of molecular sciences 2022 Dec 23;24(1)
International journal of molecular sciences 2022 Dec 23;24(1)
ADAR1p110 promotes Enterovirus D68 replication through its deaminase domain and inhibition of PKR pathway.
Zhang K, Wang S, Chen T, Tu Z, Huang X, Zang G, Wu C, Fan X, Liu J, Tian Y, Cheng Y, Lu N, Zhang G
Virology journal 2022 Dec 22;19(1):222
Virology journal 2022 Dec 22;19(1):222
Glucagon-like Peptide 1 Receptor Activation Inhibits Microglial Pyroptosis via Promoting Mitophagy to Alleviate Depression-like Behaviors in Diabetic Mice.
Yang F, Wang X, Qi J, Zhang K, Jiang Y, Feng B, Lv T, Yang L, Yang Q, Zhao M, Liu S, Ma X
Nutrients 2022 Dec 21;15(1)
Nutrients 2022 Dec 21;15(1)
Transcriptome and Gut Microbiota Profiling Analysis of ANIT-Induced Cholestasis and the Effects of Da-Huang-Xiao-Shi Decoction Intervention.
Wang W, Jiang S, Xu C, Tang L, Liang Y, Zhao Y, Zhu G
Microbiology spectrum 2022 Dec 21;10(6):e0324222
Microbiology spectrum 2022 Dec 21;10(6):e0324222
SRA Suppresses Antiviral Innate Immune Response in Macrophages by Limiting TBK1 K63 Ubiquitination via Deubiquitinase USP15.
Li L, Luo J, Zhu Z, Xu Q, Wang P, Chang B, Wang D, Yu L, Lu X, Zhou J, Zuo D, Chen Q
Microbiology spectrum 2022 Dec 21;10(6):e0202822
Microbiology spectrum 2022 Dec 21;10(6):e0202822
Beta-naphthoflavone and doxorubicin synergistically enhance apoptosis in human lung cancer cells by inducing doxorubicin accumulation, mitochondrial ROS generation, and JNK pathway signaling.
Hoang DH, Song M, Kovale LM, Tran QH, Choe W, Kang I, Kim SS, Ha J
Biochemical and biophysical research communications 2022 Dec 20;635:37-45
Biochemical and biophysical research communications 2022 Dec 20;635:37-45
RNA-m6A modification of HDGF mediated by Mettl3 aggravates the progression of atherosclerosis by regulating macrophages polarization via energy metabolism reprogramming.
Zheng L, Chen X, Yin Q, Gu J, Chen J, Chen M, Zhang Y, Dong M, Jiang H, Yin N, Chen H, Li X
Biochemical and biophysical research communications 2022 Dec 20;635:120-127
Biochemical and biophysical research communications 2022 Dec 20;635:120-127
ABHD16A Negatively Regulates the Palmitoylation and Antiviral Function of IFITM Proteins.
Shi X, Li X, Xu Z, Shen L, Ding Y, Chen S, Mao L, Liu W, Xu J
mBio 2022 Dec 20;13(6):e0228922
mBio 2022 Dec 20;13(6):e0228922
Dihydrotanshinone I Inhibits the Lung Metastasis of Breast Cancer by Suppressing Neutrophil Extracellular Traps Formation.
Zhao H, Liang Y, Sun C, Zhai Y, Li X, Jiang M, Yang R, Li X, Shu Q, Kai G, Han B
International journal of molecular sciences 2022 Dec 2;23(23)
International journal of molecular sciences 2022 Dec 2;23(23)
Epigenetic silencing of JAM3 promotes esophageal cancer development by activating Wnt signaling.
Yang W, Guo C, Herman JG, Zhu C, Lv H, Su X, Zhang L, Zhang M, Guo M
Clinical epigenetics 2022 Dec 2;14(1):164
Clinical epigenetics 2022 Dec 2;14(1):164
Titania-Nanotube-Coated Titanium Substrates Promote Osteogenesis and Suppress Osteoclastogenesis via Integrin ανβ3.
Kang H, Dong Y, Liu H, Luo C, Song H, Zhu M, Guo Q, Peng R, Li F, Li Y
ACS applied bio materials 2022 Dec 19;5(12):5832-5843
ACS applied bio materials 2022 Dec 19;5(12):5832-5843
Thrombus Inhibition and Neuroprotection for Ischemic Stroke Treatment through Platelet Regulation and ROS Scavenging.
Ye H, Ma Z, Liu L, Zhang T, Han Q, Xiang Z, Xia Y, Ke Y, Guan X, Shi Q, Ataullakhanov FI, Panteleev M
ChemMedChem 2022 Dec 16;17(24):e202200317
ChemMedChem 2022 Dec 16;17(24):e202200317
The Photoperiod Regulates Granulosa Cell Apoptosis through the FSH-Nodal/ALK7 Signaling Pathway in Phodopus sungorus.
Qi Y, Xue HL, Zheng YJ, Yin YF, Xu WL, Xu JH, Wu M, Chen L, Xu LX
Animals : an open access journal from MDPI 2022 Dec 16;12(24)
Animals : an open access journal from MDPI 2022 Dec 16;12(24)
Verteporfin inhibits the dedifferentiation of tubular epithelial cells via TGF-β1/Smad pathway but induces podocyte loss in diabetic nephropathy.
Qi C, Hu Y, Zeng M, Chen H, Shi J, Jue H, Zhao Z, Liu J, Zhang Z, Xu Y, Wu H
Life sciences 2022 Dec 15;311(Pt B):121186
Life sciences 2022 Dec 15;311(Pt B):121186
An electrochemical nitric oxide generator for in-home inhalation therapy in pulmonary artery hypertension.
Liu Y, Zhu Y, Jiang C, Su Z, Yan Y, Feng B, Mao W, Zhang Y, Wang X, Xu Z, Zhang H
BMC medicine 2022 Dec 15;20(1):481
BMC medicine 2022 Dec 15;20(1):481
Histone Deacetylase Inhibitor Panobinostat Benefits the Therapeutic Efficacy of Oncolytic Herpes Simplex Virus Combined with PD-1/PD-L1 Blocking in Glioma and Squamous Cell Carcinoma Models.
Wu Y, Chen X, Wang L, Zhou X, Liu Y, Ji D, Ren P, Zhou GG, Zhao J
Viruses 2022 Dec 15;14(12)
Viruses 2022 Dec 15;14(12)
Tetrahydroxy Stilbene Glucoside Alleviates Ischemic Stroke by Regulating Conformation-Dependent Intracellular Distribution of PKM2 for M2 Macrophage Polarization.
Li M, Lu W, Meng Y, Zhang W, Wang F, Sun L, Xu Y
Journal of agricultural and food chemistry 2022 Dec 14;70(49):15449-15463
Journal of agricultural and food chemistry 2022 Dec 14;70(49):15449-15463
Nanosilica-Anchored Polycaprolactone/Chitosan Nanofibrous Bioscaffold to Boost Osteogenesis for Bone Tissue Engineering.
Ge S, Zhu X, Zhang C, Jia D, Shang W, Ding C, Yang J, Feng Y
Molecules (Basel, Switzerland) 2022 Dec 13;27(24)
Molecules (Basel, Switzerland) 2022 Dec 13;27(24)
The protective effects of sulforaphane on high-fat diet-induced metabolic associated fatty liver disease in mice via mediating the FXR/LXRα pathway.
Ma S, Pang X, Tian S, Sun J, Hu Q, Li X, Lu Y
Food & function 2022 Dec 13;13(24):12966-12982
Food & function 2022 Dec 13;13(24):12966-12982
FOXA1 is a transcriptional activator of Odf2/Cenexin and regulates primary ciliation.
Czerny CC, Borschel A, Cai M, Otto M, Hoyer-Fender S
Scientific reports 2022 Dec 12;12(1):21468
Scientific reports 2022 Dec 12;12(1):21468
Menadione Potentiates Auranofin-Induced Glioblastoma Cell Death.
Szeliga M, Rola R
International journal of molecular sciences 2022 Dec 11;23(24)
International journal of molecular sciences 2022 Dec 11;23(24)
The Role of Apoptosis and Autophagy in the Hypothalamic-Pituitary-Adrenal (HPA) Axis after Traumatic Brain Injury (TBI).
Taheri S, Karaca Z, Mehmetbeyoglu E, Hamurcu Z, Yilmaz Z, Dal F, Çınar V, Ulutabanca H, Tanriverdi F, Unluhizarci K, Rassoulzadegan M, Kelestimur F
International journal of molecular sciences 2022 Dec 10;23(24)
International journal of molecular sciences 2022 Dec 10;23(24)
Novel bioactive hybrid Celecoxib-HDAC Inhibitor, induces apoptosis in human acute lymphoblastic leukemia cells.
Liu J, Zhang L, Guo L, Zeng Y, Guo Q, Yang C, Shu J, Liu W, Yang L
Bioorganic & medicinal chemistry 2022 Dec 1;75:117085
Bioorganic & medicinal chemistry 2022 Dec 1;75:117085
Intracameral Injection of AAV-DJ.COMP-ANG1 Reduces the IOP of Mice by Reshaping the Trabecular Outflow Pathway.
Qiao Y, Sun Z, Tan C, Lai J, Sun X, Chen J
Investigative ophthalmology & visual science 2022 Dec 1;63(13):15
Investigative ophthalmology & visual science 2022 Dec 1;63(13):15
Exposure to melamine cyanuric acid in adult mice caused motor activity and skeletal muscle energy metabolism disorder.
Wang S, Zuo X, Xu B, Yu Q, An Z, Feng D, Feng X
Physiology & behavior 2022 Dec 1;257:113990
Physiology & behavior 2022 Dec 1;257:113990
Identification of endocrine-disrupting chemicals targeting the genes and pathways of genital anomalies in males.
Zhou X, Zhang X, Zhou X, Abulimiti G, Wang Y, Zhang Q, Cong R, Ji C, Luan J, Yao L, Yang J, Song N
Ecotoxicology and environmental safety 2022 Dec 1;247:114241
Ecotoxicology and environmental safety 2022 Dec 1;247:114241
Host-induced gene silencing of PcCesA3 and PcOSBP1 confers resistance to Phytophthora capsici in Nicotiana benthamiana through NbDCL3 and NbDCL4 processed small interfering RNAs.
Wang Z, Gao X, Zhong S, Li Y, Shi M, Zhang B, Zhang S, Shen H, Liu X
International journal of biological macromolecules 2022 Dec 1;222(Pt B):1665-1675
International journal of biological macromolecules 2022 Dec 1;222(Pt B):1665-1675
Role of the cGAS-STING Pathway in Aging-related Endothelial Dysfunction.
Yu H, Liao K, Hu Y, Lv D, Luo M, Liu Q, Huang L, Luo S
Aging and disease 2022 Dec 1;13(6):1901-1918
Aging and disease 2022 Dec 1;13(6):1901-1918
Effects of the probiotic, Lactobacillus rhamnosus GG, on ulcer pathogenesis, HSP70 stress protein and nitric oxide levels in stress induced ulcer.
Isik M, Ozbayer C, Donmez DB, Colak E, Ustuner MC, Erol K, Degirmenci I
Biotechnic & histochemistry : official publication of the Biological Stain Commission 2022 Aug;97(6):449-460
Biotechnic & histochemistry : official publication of the Biological Stain Commission 2022 Aug;97(6):449-460
Ubiquitin-specific protease 47 regulates intestinal inflammation through deubiquitination of TRAF6 in epithelial cells.
Lei H, Yang L, Xu H, Wang Z, Li X, Liu M, Wu Y
Science China. Life sciences 2022 Aug;65(8):1624-1635
Science China. Life sciences 2022 Aug;65(8):1624-1635
Brown-fat-mediated tumour suppression by cold-altered global metabolism.
Seki T, Yang Y, Sun X, Lim S, Xie S, Guo Z, Xiong W, Kuroda M, Sakaue H, Hosaka K, Jing X, Yoshihara M, Qu L, Li X, Chen Y, Cao Y
Nature 2022 Aug;608(7922):421-428
Nature 2022 Aug;608(7922):421-428
Circular RNA expression profile of H(2)O(2) induced ferroptosis model of human coronary artery endothelial cells.
Hou C, Wang Y, Wang Y, Zhou Y, Hua L, Chen J, He S, Zhang S, Jia E
Atherosclerosis plus 2022 Aug;49:1-11
Atherosclerosis plus 2022 Aug;49:1-11
Corn oligopeptides inhibit Akt/NF-κB signaling pathway and inflammatory factors to ameliorate CCl(4) -induced hepatic fibrosis in mice.
Feng XW, Cheng QL, Fang L, Liu WY, Liu LW, Sun CQ, Lu ZH, Li GM, Gu RZ
Journal of food biochemistry 2022 Aug;46(8):e14162
Journal of food biochemistry 2022 Aug;46(8):e14162
Lupeol triggers oxidative stress, ferroptosis, apoptosis and restrains inflammation in nasopharyngeal carcinoma via AMPK/NF-κB pathway.
Zhou JC, Wu B, Zhang JJ, Zhang W
Immunopharmacology and immunotoxicology 2022 Aug;44(4):621-631
Immunopharmacology and immunotoxicology 2022 Aug;44(4):621-631
Protective role of selenium on MPP(+) and homocysteine-induced TRPM2 channel activation in SH-SY5Y cells.
Yıldızhan K, Nazıroğlu M
Journal of receptor and signal transduction research 2022 Aug;42(4):399-408
Journal of receptor and signal transduction research 2022 Aug;42(4):399-408
Sodium selenite attenuates zearalenone-induced apoptosis through inhibition of endoplasmic reticulum stress in goat trophoblast cells.
Xiong Y, Li B, Li J, Jin E, He S
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2022 Aug;35(4):699-710
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2022 Aug;35(4):699-710
XIST sponges miR-320d to promote chordoma progression by regulating ARF6.
Wang Y, Tang Z, Guo W
Journal of bone oncology 2022 Aug;35:100447
Journal of bone oncology 2022 Aug;35:100447
Hsa_circ_0008234 facilitates proliferation of cutaneous squamous cell carcinoma through targeting miR-127-5p to regulate ADCY7.
Cai L, Wang Y, Wu J, Wu G
Archives of dermatological research 2022 Aug;314(6):541-551
Archives of dermatological research 2022 Aug;314(6):541-551
Silencing of Rab23 by siRNA inhibits ultraviolet B-induced melanogenesis via downregulation of PKA/CREB/MITF.
Wei X, Huang M, Yang Y, Liu Y, Chi S, Li C
Experimental dermatology 2022 Aug;31(8):1253-1263
Experimental dermatology 2022 Aug;31(8):1253-1263
Iron oxide nanoparticles oxidize transformed RAW 264.7 macrophages into foam cells: Impact of pulmonary surfactant component dipalmitoylphosphatidylcholine.
Li H, Tao X, Song E, Song Y
Chemosphere 2022 Aug;300:134617
Chemosphere 2022 Aug;300:134617
Pyroptosis participates in PM(2.5)-induced air-blood barrier dysfunction.
Jia R, Wei M, Zhang X, Du R, Sun W, Wang L, Song L
Environmental science and pollution research international 2022 Aug;29(40):60987-60997
Environmental science and pollution research international 2022 Aug;29(40):60987-60997
Wnt3a knockdown promotes collagen type II expression in rat chondrocytes.
Shi S, Man Z, Sun S
Experimental and therapeutic medicine 2022 Aug;24(2):526
Experimental and therapeutic medicine 2022 Aug;24(2):526
miR-let-7c-3p targeting on Egr-1 contributes to the committed differentiation of leukemia cells into monocyte/macrophages.
Qi F, Wang X, Zhao S, Wang C, Sun R, Wang H, Du P, Wang J, Wang X, Jiang G
Oncology letters 2022 Aug;24(2):273
Oncology letters 2022 Aug;24(2):273
PM2.5-Induced Programmed Myocardial Cell Death via mPTP Opening Results in Deteriorated Cardiac Function in HFpEF Mice.
Wu T, Tong M, Chu A, Wu K, Niu X, Zhang Z
Cardiovascular toxicology 2022 Aug;22(8):746-762
Cardiovascular toxicology 2022 Aug;22(8):746-762
Ginsenoside CK induces apoptosis in triple-negative breast cancer cells by targeting glutamine metabolism.
Zhang B, Fu R, Duan Z, Shen S, Zhu C, Fan D
Biochemical pharmacology 2022 Aug;202:115101
Biochemical pharmacology 2022 Aug;202:115101
Essential role of MALAT1 in reducing traumatic brain injury.
Wu N, Cheng CJ, Zhong JJ, He JC, Zhang ZS, Wang ZG, Sun XC, Liu H
Neural regeneration research 2022 Aug;17(8):1776-1784
Neural regeneration research 2022 Aug;17(8):1776-1784
Polystyrene micro- and nano-particle coexposure injures fetal thalamus by inducing ROS-mediated cell apoptosis.
Yang D, Zhu J, Zhou X, Pan D, Nan S, Yin R, Lei Q, Ma N, Zhu H, Chen J, Han L, Ding M, Ding Y
Environment international 2022 Aug;166:107362
Environment international 2022 Aug;166:107362
α-Terthienyl induces prostate cancer cell death through inhibiting androgen receptor expression.
Gan X, Huang H, Wen J, Liu K, Yang Y, Li X, Fang G, Liu Y, Wang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Aug;152:113266
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Aug;152:113266
Upregulated LINC01088 facilitates malignant phenotypes and immune escape of colorectal cancer by regulating microRNAs/G3BP1/PD-L1 axis.
Li C, Pan B, Wang X, Liu X, Qin J, Gao T, Sun H, Pan Y, Wang S
Journal of cancer research and clinical oncology 2022 Aug;148(8):1965-1982
Journal of cancer research and clinical oncology 2022 Aug;148(8):1965-1982
LncRNA-CCAT1/miR-152-3p is involved in CSE-induced inflammation in HBE cells via regulating ERK signaling pathway.
Zong D, Liu X, Li J, Long Y, Ouyang R, Chen Y
International immunopharmacology 2022 Aug;109:108818
International immunopharmacology 2022 Aug;109:108818
Overexpression of heat shock protein 70 induces apoptosis of intestinal epithelial cells in heat-stressed pigs: A proteomics approach.
Yong Y, Li J, Yu T, Fang B, Liu X, Yu Z, Ma X, Gooneratne R, Abd El-Aty AM, Ju X
Journal of thermal biology 2022 Aug;108:103289
Journal of thermal biology 2022 Aug;108:103289
Artesunate Inhibits the Cell Growth in Colorectal Cancer by Promoting ROS-Dependent Cell Senescence and Autophagy.
Huang Z, Gan S, Zhuang X, Chen Y, Lu L, Wang Y, Qi X, Feng Q, Huang Q, Du B, Zhang R, Liu Z
Cells 2022 Aug 9;11(16)
Cells 2022 Aug 9;11(16)
Transient and Prolonged Activation of Wnt Signaling Contribute Oppositely to the Pathogenesis of Asherman's Syndrome.
Xue X, Li X, Yao J, Zhang X, Ren X, Xu S
International journal of molecular sciences 2022 Aug 8;23(15)
International journal of molecular sciences 2022 Aug 8;23(15)
Conditional knockout of ASK1 in microglia/macrophages attenuates epileptic seizures and long-term neurobehavioural comorbidities by modulating the inflammatory responses of microglia/macrophages.
Zhang Y, Wang Z, Wang R, Xia L, Cai Y, Tong F, Gao Y, Ding J, Wang X
Journal of neuroinflammation 2022 Aug 8;19(1):202
Journal of neuroinflammation 2022 Aug 8;19(1):202
Chemical profile and miscarriage prevention evaluation of Jiao-Ai Decoction, a classical traditional Chinese formula.
Zhang M, Geng T, Jing SH, Li L, Wang K, Zhang Q, Zhang Y, Zhou SK, Gao P, Ding AW, Zhang L
Journal of pharmaceutical and biomedical analysis 2022 Aug 5;217:114832
Journal of pharmaceutical and biomedical analysis 2022 Aug 5;217:114832
Expression Profile and Localization of SARS-CoV-2 Nonstructural Replicase Proteins in Infected Cells.
Shi FS, Yu Y, Li YL, Cui L, Zhao Z, Wang M, Wang B, Zhang R, Huang YW
Microbiology spectrum 2022 Aug 31;10(4):e0074422
Microbiology spectrum 2022 Aug 31;10(4):e0074422
Mucin O-glycan-microbiota axis orchestrates gut homeostasis in a diarrheal pig model.
Xia B, Zhong R, Wu W, Luo C, Meng Q, Gao Q, Zhao Y, Chen L, Zhang S, Zhao X, Zhang H
Microbiome 2022 Aug 31;10(1):139
Microbiome 2022 Aug 31;10(1):139
Assembly of Celastrol to Zeolitic Imidazolate Framework-8 by Coordination as a Novel Drug Delivery Strategy for Cancer Therapy.
Wang N, Li Y, He F, Liu S, Liu Y, Peng J, Liu J, Yu C, Wang S
Pharmaceuticals (Basel, Switzerland) 2022 Aug 29;15(9)
Pharmaceuticals (Basel, Switzerland) 2022 Aug 29;15(9)
Irisin attenuates P. gingivalis-suppressed osteogenic/cementogenic differentiation of periodontal ligament cells via p38 signaling pathway.
Huang X, Xiao J, Wang X, Cao Z
Biochemical and biophysical research communications 2022 Aug 27;618:100-106
Biochemical and biophysical research communications 2022 Aug 27;618:100-106
N-acetyldopamine dimer inhibits neuroinflammation through the TLR4/NF-κB and NLRP3/Caspase-1 pathways.
Huang L, Gong L, Huo X, Lei L, Zhang Q, Hu Y, Kuang Q, Gui Y, Dai Y, Gu Y, Deng Y, Wang D, Guo D
Acta biochimica et biophysica Sinica 2022 Aug 25;55(1):23-33
Acta biochimica et biophysica Sinica 2022 Aug 25;55(1):23-33
A positive feedback loop of ARF6 activates ERK1/2 signaling pathway via DUSP6 silencing to promote pancreatic cancer progression.
Xiao B, Zhang Y, Lu Z, Chen W, An Y, Zu G, Xu X, Wu D, Yang H, Qin Y, Chen X
Acta biochimica et biophysica Sinica 2022 Aug 25;54(10):1431-1440
Acta biochimica et biophysica Sinica 2022 Aug 25;54(10):1431-1440
mTORC1 Mediates the Processes of Lysine Regulating Satellite Cells Proliferation, Apoptosis, and Autophagy.
Liu M, Yue Z, Zhang B, Li F, Liu L, Li F
Metabolites 2022 Aug 25;12(9)
Metabolites 2022 Aug 25;12(9)
Longterm Increased S100B Enhances Hippocampal Progenitor Cell Proliferation in a Transgenic Mouse Model.
Rodrigues L, Wartchow KM, Buchfelder M, Souza DO, Gonçalves CA, Kleindienst A
International journal of molecular sciences 2022 Aug 24;23(17)
International journal of molecular sciences 2022 Aug 24;23(17)
Interferon-Stimulated Gene 15 Knockout in Mice Impairs IFNα-Mediated Antiviral Activity.
Li C, He WF, Li LX, Chen J, Yang GQ, Chang HT, Liu HM
Viruses 2022 Aug 24;14(9)
Viruses 2022 Aug 24;14(9)
CD36 aggravates podocyte injury by activating NLRP3 inflammasome and inhibiting autophagy in lupus nephritis.
Lv F, He Y, Xu H, Li Y, Han L, Yan L, Lang H, Zhao Y, Zhao Z, Qi Y
Cell death & disease 2022 Aug 23;13(8):729
Cell death & disease 2022 Aug 23;13(8):729
Toxoplasma gondii dense granule protein 3 promotes endoplasmic reticulum stress-induced apoptosis by activating the PERK pathway.
Obed C, Wu M, Chen Y, An R, Cai H, Luo Q, Yu L, Wang J, Liu F, Shen J, Du J
Parasites & vectors 2022 Aug 2;15(1):276
Parasites & vectors 2022 Aug 2;15(1):276
Overexpression of NCAPG in ovarian cancer is associated with ovarian cancer proliferation and apoptosis via p38 MAPK signaling pathway.
Yu H, Zou D, Ni N, Zhang S, Zhang Q, Yang L
Journal of ovarian research 2022 Aug 19;15(1):98
Journal of ovarian research 2022 Aug 19;15(1):98
Aucubin promotes bone-fracture healing via the dual effects of anti-oxidative damage and enhancing osteoblastogenesis of hBM-MSCs.
Wang K, Zhou C, Li L, Dai C, Wang Z, Zhang W, Xu J, Zhu Y, Pan Z
Stem cell research & therapy 2022 Aug 19;13(1):424
Stem cell research & therapy 2022 Aug 19;13(1):424
BMP6 Promotes the Secretion of 17 Beta-Estradiol and Progesterone in Goat Ovarian Granulosa Cells.
Song S, Ding W, Yao H, Wang L, Li B, Wang Y, Tang X, Zhang Y, Huang D, Xu D, Zhao Z
Animals : an open access journal from MDPI 2022 Aug 19;12(16)
Animals : an open access journal from MDPI 2022 Aug 19;12(16)
LINC00941 promotes pancreatic cancer malignancy by interacting with ANXA2 and suppressing NEDD4L-mediated degradation of ANXA2.
Wang J, He Z, Liu X, Xu J, Jiang X, Quan G, Jiang J
Cell death & disease 2022 Aug 18;13(8):718
Cell death & disease 2022 Aug 18;13(8):718
Si-Wu Water Extracts Protect against Colonic Mucus Barrier Damage by Regulating Muc2 Mucin Expression in Mice Fed a High-Fat Diet.
Ruan Z, Yu Y, Han P, Zhang L, Hu Z
Foods (Basel, Switzerland) 2022 Aug 18;11(16)
Foods (Basel, Switzerland) 2022 Aug 18;11(16)
Whole-exome sequencing and functional validation reveal a rare missense variant in MMP7 that confers ovarian endometriosis risk.
Liu F, Zhou J, Zhang X, Fang S, Liu R, Chen G, Luo Y, Zhang Z, Cheng Y, Wang L, Guo J, Zou Y
Human molecular genetics 2022 Aug 17;31(15):2595-2605
Human molecular genetics 2022 Aug 17;31(15):2595-2605
S-palmitoylation of PCSK9 induces sorafenib resistance in liver cancer by activating the PI3K/AKT pathway.
Sun Y, Zhang H, Meng J, Guo F, Ren D, Wu H, Jin X
Cell reports 2022 Aug 16;40(7):111194
Cell reports 2022 Aug 16;40(7):111194
Porcine Enteric Coronavirus PEDV Induces the ROS-ATM and Caspase7-CAD-γH2AX Signaling Pathways to Foster Its Replication.
Ming X, Chen H, Yang Y, Zhao P, Sun L, Zhang C, Shin HJ, Lee JS, Jung YS, Qian Y
Viruses 2022 Aug 15;14(8)
Viruses 2022 Aug 15;14(8)
FAM107A Inactivation Associated with Promoter Methylation Affects Prostate Cancer Progression through the FAK/PI3K/AKT Pathway.
Ke S, Liu Z, Wang Q, Zhai G, Shao H, Yu X, Guo J
Cancers 2022 Aug 13;14(16)
Cancers 2022 Aug 13;14(16)
12/15-Lipoxygenase Regulation of Diabetic Cognitive Dysfunction Is Determined by Interfering with Inflammation and Cell Apoptosis.
Chen Q, Zheng Q, Yang Y, Luo Y, Wang H, Li H, Yang L, Hu C, Zhang J, Li Y, Xia H, Chen Z, Ma J, Tian X, Yang J
International journal of molecular sciences 2022 Aug 12;23(16)
International journal of molecular sciences 2022 Aug 12;23(16)
Identification of HMGB2 associated with proliferation, invasion and prognosis in lung adenocarcinoma via weighted gene co-expression network analysis.
Qiu X, Liu W, Zheng Y, Zeng K, Wang H, Sun H, Dai J
BMC pulmonary medicine 2022 Aug 12;22(1):310
BMC pulmonary medicine 2022 Aug 12;22(1):310
The comprehensive expression and functional analysis of m6A modification "readers" in hepatocellular carcinoma.
Qin S, Liu G, Jin H, Chen X, He J, Xiao J, Qin Y, Mao Y, Zhao L
Aging 2022 Aug 12;14(15):6269-6298
Aging 2022 Aug 12;14(15):6269-6298
Preliminary evaluation of a small interfering RNA molecular probe targeting murine double minute 2 in breast cancer.
Wang X, Xu P, Jiao Y, Luan S, Gao Y, Zhao C, Fu P
Nuclear medicine communications 2022 Aug 1;43(8):869-876
Nuclear medicine communications 2022 Aug 1;43(8):869-876
San-Wu-Huang-Qin decoction attenuates tumorigenesis and mucosal barrier impairment in the AOM/DSS model by targeting gut microbiome.
Zhou Y, Feng Y, Cen R, Hou X, Yu H, Sun J, Zhou L, Ji Q, Zhao L, Wang Y, Li Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Apr;98:153966
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Apr;98:153966
Ketogenesis acts as an endogenous protective programme to restrain inflammatory macrophage activation during acute pancreatitis.
Zhang L, Shi J, Du D, Niu N, Liu S, Yang X, Lu P, Shen X, Shi N, Yao L, Zhang R, Hu G, Lu G, Zhu Q, Zeng T, Liu T, Xia Q, Huang W, Xue J
EBioMedicine 2022 Apr;78:103959
EBioMedicine 2022 Apr;78:103959
HepaCAM‑PIK3CA axis regulates the reprogramming of glutamine metabolism to inhibit prostate cancer cell proliferation.
He Z, Gao Y, Li T, Yu C, Ou L, Luo C
International journal of oncology 2022 Apr;60(4)
International journal of oncology 2022 Apr;60(4)
Acetyl CoA synthase 2 potentiates ATG5-induced autophagy against neuronal apoptosis after subarachnoid hemorrhage.
He W, Zhou X, Wu Q, Zhou L, Zhang Z, Zhang R, Deng C, Zhang X
Journal of molecular histology 2022 Apr;53(2):511-521
Journal of molecular histology 2022 Apr;53(2):511-521
Necrostatin-1 Against Sevoflurane-Induced Cognitive Dysfunction Involves Activation of BDNF/TrkB Pathway and Inhibition of Necroptosis in Aged Rats.
Yin C, Zhang Q, Zhao J, Li Y, Yu J, Li W, Wang Q
Neurochemical research 2022 Apr;47(4):1060-1072
Neurochemical research 2022 Apr;47(4):1060-1072
High‑glucose microenvironment promotes perineural invasion of pancreatic cancer via activation of hypoxia inducible factor 1α.
Zhang L, Zhang W, Zhang X, Min Y, Zhao Y, Wang B, Li W, Mao S, Min W
Oncology reports 2022 Apr;47(4)
Oncology reports 2022 Apr;47(4)
Alda-1, an Aldehyde Dehydrogenase 2 Agonist, Improves Cutaneous Wound Healing by Activating Epidermal Keratinocytes via Akt/GSK-3β/β-Catenin Pathway.
Zhang SM, Yang Z, Qi FZ
Aesthetic plastic surgery 2022 Apr;46(Suppl 1):126-127
Aesthetic plastic surgery 2022 Apr;46(Suppl 1):126-127
Tumor-specific nitric oxide generator to amplify peroxynitrite based on highly penetrable nanoparticles for metastasis inhibition and enhanced cancer therapy.
Shi M, Zhang J, Wang Y, Peng C, Hu H, Qiao M, Zhao X, Chen D
Biomaterials 2022 Apr;283:121448
Biomaterials 2022 Apr;283:121448
Tumor-promoting mechanisms of macrophage-derived extracellular vesicles-enclosed microRNA-660 in breast cancer progression.
Li C, Li R, Hu X, Zhou G, Jiang G
Breast cancer research and treatment 2022 Apr;192(2):353-368
Breast cancer research and treatment 2022 Apr;192(2):353-368
Nicotinamide riboside promotes Mfn2-mediated mitochondrial fusion in diabetic hearts through the SIRT1-PGC1α-PPARα pathway.
Hu L, Guo Y, Song L, Wen H, Sun N, Wang Y, Qi B, Liang Q, Geng J, Liu X, Fu F, Li Y
Free radical biology & medicine 2022 Apr;183:75-88
Free radical biology & medicine 2022 Apr;183:75-88
Synthesis of potent antagonists of receptors for growth hormone-releasing hormone with antitumor and anti-inflammatory activity.
Cai R, Zhang X, Wang H, Cui T, Halmos G, Sha W, He J, Popovics P, Vidaurre I, Zhang C, Mirsaeidi M, Schally AV
Peptides 2022 Apr;150:170716
Peptides 2022 Apr;150:170716
U2 small nuclear RNA auxiliary factor 2, transcriptionally activated by the transcription factor Dp-1/E2F transcription factor 1 complex, enhances the growth and aerobic glycolysis of leiomyosarcoma cells.
Li Y, Chen S, Zhang X, Zhuo N
Bioengineered 2022 Apr;13(4):10200-10212
Bioengineered 2022 Apr;13(4):10200-10212
Baicalein suppresses high glucose-induced inflammation and apoptosis in trophoblasts by targeting the miRNA-17-5p-Mfn1/2-NF-κB pathway.
Li J, Wang Y, Wu T, Li S, Sun YN, Liu ZH
Placenta 2022 Apr;121:126-136
Placenta 2022 Apr;121:126-136
Myeloid peroxisome proliferator-activated receptor α deficiency accelerates liver regeneration via IL-6/STAT3 pathway after 2/3 partial hepatectomy in mice.
Xie G, Song Y, Li N, Zhang Z, Wang X, Liu Y, Jiao S, Wei M, Yu B, Wang Y, Wang H, Qu A
Hepatobiliary surgery and nutrition 2022 Apr;11(2):199-211
Hepatobiliary surgery and nutrition 2022 Apr;11(2):199-211
Clostridium butyricum inhibits the progression of colorectal cancer and alleviates intestinal inflammation via the myeloid differentiation factor 88 (MyD88)-nuclear factor-kappa B (NF-κB) signaling pathway.
Zhou M, Yuan W, Yang B, Pei W, Ma J, Feng Q
Annals of translational medicine 2022 Apr;10(8):478
Annals of translational medicine 2022 Apr;10(8):478
Ibandronate promotes autophagy by inhibiting Rac1-mTOR signaling pathway in vitro and in vivo.
Han J, Yang J, Wang Q, Yin X, Sun Z, Huang C, Chen G, Zheng L, Jiang D
Cell death discovery 2022 Apr 9;8(1):186
Cell death discovery 2022 Apr 9;8(1):186
SorCS3 promotes the internalization of p75(NTR) to inhibit GBM progression.
Zhang Y, Li Y, Fan Y, Zhang X, Tang Z, Qi J, Zhao B, Li F, Chen X, Liang H, Xu H, Li D
Cell death & disease 2022 Apr 7;13(4):313
Cell death & disease 2022 Apr 7;13(4):313
Hydroxysafflor Yellow A Blocks HIF-1α Induction of NOX2 and Protects ZO-1 Protein in Cerebral Microvascular Endothelium.
Li Y, Liu XT, Zhang PL, Li YC, Sun MR, Wang YT, Wang SP, Yang H, Liu BL, Wang M, Gao W, Li P
Antioxidants (Basel, Switzerland) 2022 Apr 7;11(4)
Antioxidants (Basel, Switzerland) 2022 Apr 7;11(4)
LncRNA WEE2-AS1 Knockdown Inhibits the Proliferation, Migration and 3 Invasion of Glioma Cells via Regulating miR-29b-2-5p/TPM3 Axis.
Jia Z, Qian Z, Tang Y, Li X, Shi Y, Xin H, Fan Y, Wu H
Oncology research 2022 Apr 7;
Oncology research 2022 Apr 7;
Cannabis suppresses antitumor immunity by inhibiting JAK/STAT signaling in T cells through CNR2.
Xiong X, Chen S, Shen J, You H, Yang H, Yan C, Fang Z, Zhang J, Cai X, Dong X, Kang T, Li W, Zhou P
Signal transduction and targeted therapy 2022 Apr 6;7(1):99
Signal transduction and targeted therapy 2022 Apr 6;7(1):99
Citrinin-Induced Hepatotoxicity in Mice Is Regulated by the Ca(2+)/Endoplasmic Reticulum Stress Signaling Pathway.
Wu D, Yang C, Yang M, Wu Y, Mao Y, Zhou X, Wang J, Yuan Z, Wu J
Toxins 2022 Apr 6;14(4)
Toxins 2022 Apr 6;14(4)
IL-37 isoform D acts as an inhibitor of soluble ST2 to boost type 2 immune homeostasis in white adipose tissue.
Li C, Zhao M, Zhao M, Chen N, Guo Y, Du Y, Zhang Y, Cao B, Zhan B, Guo C, Li Y, Li Y, Shi Y, Zhu F, Zhang L, Wang Q
Cell death discovery 2022 Apr 5;8(1):163
Cell death discovery 2022 Apr 5;8(1):163
M1 Macrophages Enhance Survival and Invasion of Oral Squamous Cell Carcinoma by Inducing GDF15-Mediated ErbB2 Phosphorylation.
Lv C, Li S, Zhao J, Yang P, Yang C
ACS omega 2022 Apr 5;7(13):11405-11414
ACS omega 2022 Apr 5;7(13):11405-11414
Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue.
Rosina M, Ceci V, Turchi R, Chuan L, Borcherding N, Sciarretta F, Sánchez-Díaz M, Tortolici F, Karlinsey K, Chiurchiù V, Fuoco C, Giwa R, Field RL, Audano M, Arena S, Palma A, Riccio F, Shamsi F, Renzone G, Verri M, Crescenzi A, Rizza S, Faienza F, Filomeni G, Kooijman S, Rufini S, de Vries AAF, Scaloni A, Mitro N, Tseng YH, Hidalgo A, Zhou B, Brestoff JR, Aquilano K, Lettieri-Barbato D
Cell metabolism 2022 Apr 5;34(4):533-548.e12
Cell metabolism 2022 Apr 5;34(4):533-548.e12
Weighted gene co-expression network indicates that the DYNLL2 is an important regulator of chicken breast muscle development and is regulated by miR-148a-3p.
Li Y, Yuan P, Fan S, Zhai B, Jin W, Li D, Li H, Sun G, Han R, Liu X, Tian Y, Li G, Kang X
BMC genomics 2022 Apr 4;23(1):258
BMC genomics 2022 Apr 4;23(1):258
Platycodon grandiflorum root fermentation broth reduces inflammation in a mouse IBD model through the AMPK/NF-κB/NLRP3 pathway.
Wang Z, Li C, He X, Xu K, Xue Z, Wang T, Xu Z, Liu X
Food & function 2022 Apr 4;13(7):3946-3956
Food & function 2022 Apr 4;13(7):3946-3956
Sertad1 Induces Neurological Injury after Ischemic Stroke via the CDK4/p-Rb Pathway.
Li J, Li B, Bu Y, Zhang H, Guo J, Hu J, Zhang Y
Molecules and cells 2022 Apr 30;45(4):216-230
Molecules and cells 2022 Apr 30;45(4):216-230
Map of Enteropathogenic Escherichia coli Targets Mitochondria and Triggers DRP-1-Mediated Mitochondrial Fission and Cell Apoptosis in Bovine Mastitis.
Li Y, Zhu Y, Chu B, Liu N, Chen S, Wang J, Zou Y
International journal of molecular sciences 2022 Apr 28;23(9)
International journal of molecular sciences 2022 Apr 28;23(9)
Pterostilbene and Its Derivative 3'-Hydroxypterostilbene Ameliorated Nonalcoholic Fatty Liver Disease Through Synergistic Modulation of the Gut Microbiota and SIRT1/AMPK Signaling Pathway.
Tsai HY, Shih YY, Yeh YT, Huang CH, Liao CA, Hu CY, Nagabhushanam K, Ho CT, Chen YK
Journal of agricultural and food chemistry 2022 Apr 27;70(16):4966-4980
Journal of agricultural and food chemistry 2022 Apr 27;70(16):4966-4980
The NDUFV2 gene silencing inhibits the proliferation of two drug-resistant cancer cell lines.
Liu L, Wang X, Li Y, Ma C, Shi Y, Li X, Chen J
Journal, genetic engineering & biotechnology 2022 Apr 26;20(1):64
Journal, genetic engineering & biotechnology 2022 Apr 26;20(1):64
ASFV pD345L protein negatively regulates NF-κB signalling by inhibiting IKK kinase activity.
Chen H, Wang Z, Gao X, Lv J, Hu Y, Jung YS, Zhu S, Wu X, Qian Y, Dai J
Veterinary research 2022 Apr 23;53(1):32
Veterinary research 2022 Apr 23;53(1):32
MFG-E8 alleviates intervertebral disc degeneration by suppressing pyroptosis and extracellular matrix degradation in nucleus pulposus cells via Nrf2/TXNIP/NLRP3 axis.
Ma H, Xie C, Chen Z, He G, Dai Z, Cai H, Zhang H, Lu H, Wu H, Hu X, Zhou K, Zheng G, Xu H, Xu C
Cell death discovery 2022 Apr 19;8(1):209
Cell death discovery 2022 Apr 19;8(1):209
PCV2 and PRV Coinfection Induces Endoplasmic Reticulum Stress via PERK-eIF2α-ATF4-CHOP and IRE1-XBP1-EDEM Pathways.
Chen S, Li X, Zhang X, Niu G, Yang L, Ji W, Zhang L, Ren L
International journal of molecular sciences 2022 Apr 19;23(9)
International journal of molecular sciences 2022 Apr 19;23(9)
Mettl14-Mediated m6A Modification Is Essential for Germinal Center B Cell Response.
Huang H, Zhang G, Ruan GX, Li Y, Chen W, Zou J, Zhang R, Wang J, Ji SJ, Xu S, Ou X
Journal of immunology (Baltimore, Md. : 1950) 2022 Apr 15;208(8):1924-1936
Journal of immunology (Baltimore, Md. : 1950) 2022 Apr 15;208(8):1924-1936
Reticulon 2 promotes gastric cancer metastasis via activating endoplasmic reticulum Ca(2+) efflux-mediated ERK signalling.
Song S, Liu B, Zeng X, Wu Y, Chen H, Wu H, Gu J, Gao X, Ruan Y, Wang H
Cell death & disease 2022 Apr 15;13(4):349
Cell death & disease 2022 Apr 15;13(4):349
Hydrogen-generating Si-based agent protects against skin flap ischemia-reperfusion injury in rats.
Otani N, Tomita K, Kobayashi Y, Kuroda K, Koyama Y, Kobayashi H, Kubo T
Scientific reports 2022 Apr 13;12(1):6168
Scientific reports 2022 Apr 13;12(1):6168
Let-7i-5p promotes a malignant phenotype in nasopharyngeal carcinoma via inhibiting tumor-suppressive autophagy.
You B, Zhang P, Gu M, Yin H, Fan Y, Yao H, Pan S, Xie H, Cheng T, Liu H, You Y, Liu J
Cancer letters 2022 Apr 10;531:14-26
Cancer letters 2022 Apr 10;531:14-26
Effects of Exogenous ATP on Melanoma Growth and Tumor Metabolism in C57BL/6 Mice.
Lei Y, Zhou X, Zhao Y, Zhang J
Comparative medicine 2022 Apr 1;72(2):93-103
Comparative medicine 2022 Apr 1;72(2):93-103
Resveratrol attenuates methylmercury-induced neurotoxicity by modulating synaptic homeostasis.
Wang W, Deng C, Chen F, Zhang L, Hu Y, Lu Q, Zhang A
Toxicology and applied pharmacology 2022 Apr 1;440:115952
Toxicology and applied pharmacology 2022 Apr 1;440:115952
Bisphenol A impairs macrophages through inhibiting autophagy via AMPK/mTOR signaling pathway and inducing apoptosis.
Wu M, Cong Y, Wang K, Yu H, Zhang X, Ma M, Duan Z, Pei X
Ecotoxicology and environmental safety 2022 Apr 1;234:113395
Ecotoxicology and environmental safety 2022 Apr 1;234:113395
Adipose-derived stem cells alleviate liver injury induced by type 1 diabetes mellitus by inhibiting mitochondrial stress and attenuating inflammation.
Hou Y, Ding W, Wu P, Liu C, Ding L, Liu J, Wang X
Stem cell research & therapy 2022 Apr 1;13(1):132
Stem cell research & therapy 2022 Apr 1;13(1):132
Inhibition of Kelch-like epichlorohydrin-related protein 1 promotes the progression and drug resistance of lung adenocarcinoma.
Gao H, Tang P, Ni K, Zhu L, Chen S, Zheng Y, Wan Y
PeerJ 2021;9:e11908
PeerJ 2021;9:e11908
Combination of ferulic acid, ligustrazine and tetrahydropalmatine inhibits invasion and metastasis through MMP/TIMP signaling in endometriosis.
Tan Y, Zhang C, Zhang Y, Dai X, Wei Q, Wei J, Xu P, Chen Y
PeerJ 2021;9:e11664
PeerJ 2021;9:e11664
Apigenin Alleviates Intervertebral Disc Degeneration via Restoring Autophagy Flux in Nucleus Pulposus Cells.
Xie C, Shi Y, Chen Z, Zhou X, Luo P, Hong C, Tian N, Wu Y, Zhou Y, Lin Y, Dou H, Wu A, Huang Q, Zhang X, Wang X
Frontiers in cell and developmental biology 2021;9:787278
Frontiers in cell and developmental biology 2021;9:787278
Single-Cell Analysis Identify Transcription Factor BACH1 as a Master Regulator Gene in Vascular Cells During Aging.
Ge F, Pan Q, Qin Y, Jia M, Ruan C, Wei X, Jing Q, Zhi X, Wang X, Jiang L, Osto E, Guo J, Meng D
Frontiers in cell and developmental biology 2021;9:786496
Frontiers in cell and developmental biology 2021;9:786496
Hypoxia Activates Notch4 via ERK/JNK/P38 MAPK Signaling Pathways to Promote Lung Adenocarcinoma Progression and Metastasis.
Li X, Cao X, Zhao H, Guo M, Fang X, Li K, Qin L, He Y, Liu X
Frontiers in cell and developmental biology 2021;9:780121
Frontiers in cell and developmental biology 2021;9:780121
CTRP1 Attenuates Cerebral Ischemia/Reperfusion Injury via the PERK Signaling Pathway.
Fei H, Xiang P, Luo W, Tan X, Gu C, Liu M, Chen M, Wang Q, Yang J
Frontiers in cell and developmental biology 2021;9:700854
Frontiers in cell and developmental biology 2021;9:700854
Effect of Sirolimus on the Level of Peripheral Blood Lymphocyte Autophagy in Children With Systemic Lupus Erythematosus.
Wang X, Su Q, Dou Z, Zhao X, Zhang N, Yu B, Wang Y, Rong Z
Frontiers in pediatrics 2021;9:685497
Frontiers in pediatrics 2021;9:685497
Targeted Deletion of Loxl3 by Col2a1-Cre Leads to Progressive Hearing Loss.
Liu Z, Bai X, Wan P, Mo F, Chen G, Zhang J, Gao J
Frontiers in cell and developmental biology 2021;9:683495
Frontiers in cell and developmental biology 2021;9:683495
Osteopontin N-Terminal Function in an Abdominal Aortic Aneurysm From Apolipoprotein E-Deficient Mice.
Liu H, Zhang Y, Song W, Sun Y, Jiang Y
Frontiers in cell and developmental biology 2021;9:681790
Frontiers in cell and developmental biology 2021;9:681790
Estrogen Receptor α Mediates Doxorubicin Sensitivity in Breast Cancer Cells by Regulating E-Cadherin.
Wan X, Hou J, Liu S, Zhang Y, Li W, Zhang Y, Ding Y
Frontiers in cell and developmental biology 2021;9:583572
Frontiers in cell and developmental biology 2021;9:583572
Tooth Loss Induces Memory Impairment and Gliosis in App Knock-In Mouse Models of Alzheimer's Disease.
Taslima F, Jung CG, Zhou C, Abdelhamid M, Abdullah M, Goto T, Saito T, Saido TC, Michikawa M
Journal of Alzheimer's disease : JAD 2021;80(4):1687-1704
Journal of Alzheimer's disease : JAD 2021;80(4):1687-1704
Celastrol Inhibits Canine Mammary Tumor Cells by Inducing Apoptosis via the Caspase Pathway.
Ou G, Jiang X, Gao A, Li X, Lin Z, Pei S
Frontiers in veterinary science 2021;8:801407
Frontiers in veterinary science 2021;8:801407
Depiction of Aging-Based Molecular Phenotypes With Diverse Clinical Prognosis and Immunological Features in Gastric Cancer.
He F, Ding H, Zhou Y, Wang Y, Xie J, Yang S, Zhu Y
Frontiers in medicine 2021;8:792740
Frontiers in medicine 2021;8:792740
Identification of a Three-Glycolysis-Related lncRNA Signature Correlated With Prognosis and Metastasis in Clear Cell Renal Cell Carcinoma.
Li T, Tong H, Zhu J, Qin Z, Yin S, Sun Y, Liu X, He W
Frontiers in medicine 2021;8:777507
Frontiers in medicine 2021;8:777507
Comprehensive Analysis of the Potential Immune-Related Biomarker Transporter Associated With Antigen Processing 1 That Inhibits Metastasis and Invasion of Ovarian Cancer Cells.
Li X, Zeng S, Ding Y, Nie Y, Yang M
Frontiers in molecular biosciences 2021;8:763958
Frontiers in molecular biosciences 2021;8:763958
RhoA/ROCK-YAP/TAZ Axis Regulates the Fibrotic Activity in Dexamethasone-Treated Human Trabecular Meshwork Cells.
Liu Z, Li S, Qian X, Li L, Zhang H, Liu Z
Frontiers in molecular biosciences 2021;8:728932
Frontiers in molecular biosciences 2021;8:728932
Transcriptome Differences in Pig Tracheal Epithelial Cells in Response to Pasteurella Multocida Infection.
Wang X, Wang F, Lin L, Liang W, Liu S, Hua L, Wang X, Chen H, Peng Z, Wu B
Frontiers in veterinary science 2021;8:682514
Frontiers in veterinary science 2021;8:682514
Indoleamine-2,3-Dioxygenase Activates Wnt/β-Catenin Inducing Kidney Fibrosis after Acute Kidney Injury.
Pan B, Zhang H, Hong Y, Ma M, Wan X, Cao C
Gerontology 2021;67(5):611-619
Gerontology 2021;67(5):611-619
Transient Receptor Potential Melastatin 7 Promotes Vascular Adventitial Fibroblasts Phenotypic Transformation and Inflammatory Reaction Induced by Mechanical Stretching Stress via p38 MAPK/JNK Pathway.
Liu J, Chen L, Huang J, Guo S, Zhu D, Gao P
Journal of vascular research 2021;58(2):108-120
Journal of vascular research 2021;58(2):108-120
LncRNA WEE2-AS1 knockdown inhibits the proliferation, migration and invasion of glioma cells via regulating miR-29b-2-5p/TPM3 axis.
Jia Z, Qian Z, Tang Y, Li X, Shi Y, Xin H, Fan Y, Wu H
Oncology research 2021;29(2):105-117
Oncology research 2021;29(2):105-117
Study on Protection of Human Umbilical Vein Endothelial Cells from Amiodarone-Induced Damage by Intermedin through Activation of Wnt/β-Catenin Signaling Pathway.
Wang Y, Wang J, Yang J, Kang J, Xue F, Chang S, Ji H, Zang H, Zhou X, Wang G, Fan W, Yan X, Guo J, Ren X, Tian J
Oxidative medicine and cellular longevity 2021;2021:8889408
Oxidative medicine and cellular longevity 2021;2021:8889408
Secretagogin Mediates the Regulatory Effect of Electroacupuncture on Hypothalamic-Pituitary-Adrenal Axis Dysfunction in Surgical Trauma.
Zhang M, Sun J, Wang Y, Tian Z
Neural plasticity 2021;2021:8881136
Neural plasticity 2021;2021:8881136
Human Tissue Kallikrein 1 Is Downregulated in Elderly Human Prostates and Possesses Potential In Vitro Antioxidative and Antifibrotic Effects in Rodent Prostates.
Zhang M, Luo C, Lin D, Cui K, Chen Z, Liu J
Oxidative medicine and cellular longevity 2021;2021:8877540
Oxidative medicine and cellular longevity 2021;2021:8877540
Inhibition of Growth of Colon Tumors and Proliferation of HT-29 Cells by Warburgia ugandensis Extract through Mediating G(0)/G(1) Cell Cycle Arrest, Cell Apoptosis, and Intracellular ROS Generation.
Zhang Y, Chen G, Zhuang X, Guo M
Oxidative medicine and cellular longevity 2021;2021:8807676
Oxidative medicine and cellular longevity 2021;2021:8807676
The Formation of Melanocyte Apoptotic Bodies in Vitiligo and the Relocation of Vitiligo Autoantigens under Oxidative Stress.
Tian J, Wang Y, Ding M, Zhang Y, Chi J, Wang T, Jiao B, Jian Z, Yi X, Huang Y, Liu L, Li K, Chen J, Wang G, Gao T, Li C, Li Q
Oxidative medicine and cellular longevity 2021;2021:7617839
Oxidative medicine and cellular longevity 2021;2021:7617839
HMSC-Derived Exosome Inhibited Th2 Cell Differentiation via Regulating miR-146a-5p/SERPINB2 Pathway.
Zhou J, Lu Y, Wu W, Feng Y
Journal of immunology research 2021;2021:6696525
Journal of immunology research 2021;2021:6696525
MCU That Is Transcriptionally Regulated by Nrf2 Augments Malignant Biological Behaviors in Oral Squamous Cell Carcinoma Cells.
Wu R, Zuo W, Xu X, Bi L, Zhang C, Chen H, Liu H
BioMed research international 2021;2021:6650791
BioMed research international 2021;2021:6650791
Decreased Expression of MPC2 Contributes to Aerobic Glycolysis and Colorectal Cancer Proliferation by Activating mTOR Pathway.
Kuerbanjiang M, Gu L, Xu C, Xu WT, Wen S, Xue H, Xu Q
Journal of immunology research 2021;2021:6618837
Journal of immunology research 2021;2021:6618837
Antioral Squamous Cell Carcinoma Effects of Carvacrol via Inhibiting Inflammation, Proliferation, and Migration Related to Nrf2/Keap1 Pathway.
Liu H, Xu X, Wu R, Bi L, Zhang C, Chen H, Yang Y
BioMed research international 2021;2021:6616547
BioMed research international 2021;2021:6616547
Metformin-Induced MicroRNA-34a-3p Downregulation Alleviates Senescence in Human Dental Pulp Stem Cells by Targeting CAB39 through the AMPK/mTOR Signaling Pathway.
Zhang S, Zhang R, Qiao P, Ma X, Lu R, Wang F, Li C, E L, Liu H
Stem cells international 2021;2021:6616240
Stem cells international 2021;2021:6616240
DCI after Aneurysmal Subarachnoid Hemorrhage Is Related to the Expression of MFG-E8.
Chen X, Jiang Y, Liu J, Wang C, Wan D, Liang A, Leng J, Yang Y, Xiang H, Liu R
BioMed research international 2021;2021:6568477
BioMed research international 2021;2021:6568477
Anterior Gradient Protein 2 Promotes Mucosal Repair in Pediatric Ulcerative Colitis.
Ye X, Wu J, Li J, Wang H
BioMed research international 2021;2021:6483860
BioMed research international 2021;2021:6483860
SPP1 Promotes Enzalutamide Resistance and Epithelial-Mesenchymal-Transition Activation in Castration-Resistant Prostate Cancer via PI3K/AKT and ERK1/2 Pathways.
Pang X, Zhang J, He X, Gu Y, Qian BZ, Xie R, Yu W, Zhang X, Li T, Shi X, Zhou Y, Cui Y
Oxidative medicine and cellular longevity 2021;2021:5806602
Oxidative medicine and cellular longevity 2021;2021:5806602
Protective Effects of Huangqi Shengmai Yin on Type 1 Diabetes-Induced Cardiomyopathy by Improving Myocardial Lipid Metabolism.
Cao Z, Pan J, Sui X, Fang C, Li N, Huang X, Qu X, Han D
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5590623
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5590623
Colonic Epithelial PHLPP2 Deficiency Promotes Colonic Epithelial Pyroptosis by Activating the NF-κB Signaling Pathway.
Li DF, Chang X, Zhao JL, Chen XM, Xu ZL, Zhang DG, Wu BH, Wang LS, Bai Y, Yao J
Oxidative medicine and cellular longevity 2021;2021:5570731
Oxidative medicine and cellular longevity 2021;2021:5570731
Exploring the Role and Mechanism of pAMPKα-Mediated Dysregulation of Brf1 and RNA Pol III Genes.
Wu T, Zhang D, Lin M, Yu L, Dai T, Li S, Yu F, Lu L, Zheng L, Zhong S
Oxidative medicine and cellular longevity 2021;2021:5554932
Oxidative medicine and cellular longevity 2021;2021:5554932
Berberine Reduces Renal Cell Pyroptosis in Golden Hamsters with Diabetic Nephropathy through the Nrf2-NLRP3-Caspase-1-GSDMD Pathway.
Ding B, Geng S, Hou X, Ma X, Xu H, Yang F, Liu K, Liang W, Ma G
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5545193
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5545193
QiShenYiQi Pill Improves Myocardial Hypertrophy Caused by Pressure Overload in Rats.
Lv S, Wang Q, Wu M, Li M, Wang X, Xu L, Zhang J
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5536723
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5536723
Lycopene-Loaded Microemulsion Regulates Neurogenesis in Rats with Aβ-Induced Alzheimer's Disease Rats Based on the Wnt/β-catenin Pathway.
Ning WJ, Lv RJ, Xu N, Hou XY, Shen C, Guo YL, Fan ZY, Cao N, Liu XP
Neural plasticity 2021;2021:5519330
Neural plasticity 2021;2021:5519330
Saikosaponin D Inhibits the Proliferation and Promotes the Apoptosis of Rat Hepatic Stellate Cells by Inducing Autophagosome Formation.
Jiang H, Liu J, Zhang K, Zeng Q
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5451758
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5451758
Sesamin Protects against and Ameliorates Rat Intestinal Ischemia/Reperfusion Injury with Involvement of Activating Nrf2/HO-1/NQO1 Signaling Pathway.
Wang Y, Wen J, Almoiliqy M, Wang Y, Liu Z, Yang X, Lu X, Meng Q, Peng J, Lin Y, Sun P
Oxidative medicine and cellular longevity 2021;2021:5147069
Oxidative medicine and cellular longevity 2021;2021:5147069
Recombinant Human Growth Hormone Inhibits Lipotoxicity, Oxidative Stress, and Apoptosis in a Mouse Model of Diabetic Cardiomyopathy.
Pei Z, Wang X, Yang C, Dong M, Wang F
Oxidative medicine and cellular longevity 2021;2021:3899356
Oxidative medicine and cellular longevity 2021;2021:3899356
ARHGEF3 Associated with Invasion, Metastasis, and Proliferation in Human Osteosarcoma.
Gong J, Tang W, Lv B, Zhang S, Fan T, Gao G, Chen D, Liu Y
BioMed research international 2021;2021:3381957
BioMed research international 2021;2021:3381957
Electroacupuncture Preconditioning Reduces Oxidative Stress in the Acute Phase of Cerebral Ischemia-Reperfusion in Rats by Regulating Iron Metabolism Pathways.
Liang R, Tang Q, Song W, Zhang M, Teng L, Kang Y, Zhu L
Evidence-based complementary and alternative medicine : eCAM 2021;2021:3056963
Evidence-based complementary and alternative medicine : eCAM 2021;2021:3056963
miRNA-27a Transcription Activated by c-Fos Regulates Myocardial Ischemia-Reperfusion Injury by Targeting ATAD3a.
Bao Y, Qiao Y, Yu H, Zhang Z, Yang H, Xin X, Chen Y, Guo Y, Wu N, Jia D
Oxidative medicine and cellular longevity 2021;2021:2514947
Oxidative medicine and cellular longevity 2021;2021:2514947
SIRT1 Attenuates Apoptosis of Nucleus Pulposus Cells by Targeting Interactions between LC3B and Fas under High-Magnitude Compression.
Zhuo Y, Wang H, Zou L, Wang Y, Hu Y, Li P, Zhou Q
Oxidative medicine and cellular longevity 2021;2021:2420969
Oxidative medicine and cellular longevity 2021;2021:2420969
Curcumin Inhibits Replication of Human Parainfluenza Virus Type 3 by Affecting Viral Inclusion Body Formation.
Zhang C, Zhang K, Zang G, Chen T, Lu N, Wang S, Zhang G
BioMed research international 2021;2021:1807293
BioMed research international 2021;2021:1807293
Metformin Corrects Glucose Metabolism Reprogramming and NLRP3 Inflammasome-Induced Pyroptosis via Inhibiting the TLR4/NF-κB/PFKFB3 Signaling in Trophoblasts: Implication for a Potential Therapy of Preeclampsia.
Zhang Y, Liu W, Zhong Y, Li Q, Wu M, Yang L, Liu X, Zou L
Oxidative medicine and cellular longevity 2021;2021:1806344
Oxidative medicine and cellular longevity 2021;2021:1806344
LncRNA H19 Upregulation Participates in the Response of Glioma Cells to Radiation.
Kuang Y, Bing Z, Jin X, Li Q
BioMed research international 2021;2021:1728352
BioMed research international 2021;2021:1728352
CircMETTL3, upregulated in a m6A-dependent manner, promotes breast cancer progression.
Li Z, Yang HY, Dai XY, Zhang X, Huang YZ, Shi L, Wei JF, Ding Q
International journal of biological sciences 2021;17(5):1178-1190
International journal of biological sciences 2021;17(5):1178-1190
Thymoquinone Suppresses the Proliferation, Migration and Invasiveness through Regulating ROS, Autophagic Flux and miR-877-5p in Human Bladder Carcinoma Cells.
Zhou X, Wang F, Wu H, Chen X, Zhang Y, Lin J, Cai Y, Xiang J, He N, Hu Z, Jin X
International journal of biological sciences 2021;17(13):3456-3475
International journal of biological sciences 2021;17(13):3456-3475
LINC00839 Regulates Proliferation, Migration, Invasion, Apoptosis and Glycolysis in Neuroblastoma Cells Through miR-338-3p/GLUT1 Axis.
Yang L, Pei L, Yi J
Neuropsychiatric disease and treatment 2021;17:2027-2040
Neuropsychiatric disease and treatment 2021;17:2027-2040
Rufinamide (RUF) suppresses inflammation and maintains the integrity of the blood-brain barrier during kainic acid-induced brain damage.
Yu H, He B, Han X, Yan T
Open life sciences 2021;16(1):845-855
Open life sciences 2021;16(1):845-855
New targets of morphine postconditioning protection of the myocardium in ischemia/reperfusion injury: Involvement of HSP90/Akt and C5a/NF-κB.
Tu RH, Wang DX, Zhong GQ, Meng JJ, Wen H, Jie-Feng, Bi Q, He Y
Open medicine (Warsaw, Poland) 2021;16(1):1552-1563
Open medicine (Warsaw, Poland) 2021;16(1):1552-1563
p53 Promoted Ferroptosis in Ovarian Cancer Cells Treated with Human Serum Incubated-Superparamagnetic Iron Oxides.
Zhang Y, Xia M, Zhou Z, Hu X, Wang J, Zhang M, Li Y, Sun L, Chen F, Yu H
International journal of nanomedicine 2021;16:283-296
International journal of nanomedicine 2021;16:283-296
Self-Assembled DNA Nanostructure as a Carrier for Targeted siRNA Delivery in Glioma Cells.
Zhou Y, Yang Q, Wang F, Zhou Z, Xu J, Cheng S, Cheng Y
International journal of nanomedicine 2021;16:1805-1817
International journal of nanomedicine 2021;16:1805-1817
Geniposide from Gardenia jasminoides var. radicans Makino Attenuates Myocardial Injury in Spontaneously Hypertensive Rats via Regulating Apoptotic and Energy Metabolism Signalling Pathway.
Hou Y, Yuan P, Fu Y, Zhang Q, Gao L, Wei Y, Zheng X, Feng W
Drug design, development and therapy 2021;15:949-962
Drug design, development and therapy 2021;15:949-962
The Ghrelin/Growth Hormone Secretagogue Receptor System Is Involved in the Rapid and Sustained Antidepressant-Like Effect of Paeoniflorin.
Zhang Y, Zhu MZ, Qin XH, Zeng YN, Zhu XH
Frontiers in neuroscience 2021;15:631424
Frontiers in neuroscience 2021;15:631424
GRIN2A Variants Associated With Idiopathic Generalized Epilepsies.
Liu XR, Xu XX, Lin SM, Fan CY, Ye TT, Tang B, Shi YW, Su T, Li BM, Yi YH, Luo JH, Liao WP
Frontiers in molecular neuroscience 2021;14:720984
Frontiers in molecular neuroscience 2021;14:720984
Gamma Radiation Induce Inflammasome Signaling and Pyroptosis in Microvascular Endothelial Cells.
Smith AO, Ju W, Adzraku SY, Wenyi L, Yuting C, Qiao J, Xu K, Zeng L
Journal of inflammation research 2021;14:3277-3288
Journal of inflammation research 2021;14:3277-3288
Curcumin-Alleviated Osteoarthritic Progression in Rats Fed a High-Fat Diet by Inhibiting Apoptosis and Activating Autophagy via Modulation of MicroRNA-34a.
Yao J, Liu X, Sun Y, Dong X, Liu L, Gu H
Journal of inflammation research 2021;14:2317-2331
Journal of inflammation research 2021;14:2317-2331
LncRNA MALAT1 promotes breast cancer progression by sponging miR101-3p to mediate mTOR/PKM2 signal transmission.
Shao J, Zhang Q, Wang P, Wang Z
American journal of translational research 2021;13(9):10262-10275
American journal of translational research 2021;13(9):10262-10275
STAT5 inhibitor attenuates atherosclerosis via inhibition of inflammation: the role of STAT5 in atherosclerosis.
Wang X, Ding X, Yan J, Lu Z, Cao H, Ni X, Ying Y
American journal of translational research 2021;13(3):1422-1431
American journal of translational research 2021;13(3):1422-1431
RNF128 suppresses the malignancy of colorectal cancer cells via inhibition of Wnt/β-catenin signaling.
Zhu Y, Gan Y, Zou R, Sha H, Lu Y, Zhang Y, Feng J
American journal of translational research 2021;13(12):13567-13578
American journal of translational research 2021;13(12):13567-13578
Novel lncRNA LINC01614 Facilitates Bladder Cancer Proliferation, Migration and Invasion Through the miR-217/RUNX2/Wnt/β-Catenin Axis.
Wang Z, Yan H, Cheng D, Xu L, Shen T, Chen Y, Han R, Xue Y
Cancer management and research 2021;13:8387-8397
Cancer management and research 2021;13:8387-8397
Calcitriol Alleviates MPP+- and MPTP-Induced Parthanatos Through the VDR/PARP1 Pathway in the Model of Parkinson's Disease.
Hu J, Wu J, Wan F, Kou L, Yin S, Sun Y, Li Y, Zhou Q, Wang T
Frontiers in aging neuroscience 2021;13:657095
Frontiers in aging neuroscience 2021;13:657095
Irisin Contributes to Neuroprotection by Promoting Mitochondrial Biogenesis After Experimental Subarachnoid Hemorrhage.
Tu T, Yin S, Pang J, Zhang X, Zhang L, Zhang Y, Xie Y, Guo K, Chen L, Peng J, Jiang Y
Frontiers in aging neuroscience 2021;13:640215
Frontiers in aging neuroscience 2021;13:640215
Ubenimex Suppresses the Ability of Migration and Invasion in Gastric Cancer Cells by Alleviating the Activity of the CD13/NAB1/MAPK Pathway.
Liu X, Guo Q, Jing F, Zhou C, Xiu T, Shi Y, Jing F
Cancer management and research 2021;13:4483-4495
Cancer management and research 2021;13:4483-4495
ARRB1 Drives Gallbladder Cancer Progression by Facilitating TAK1/MAPK Signaling Activation.
Zhang X, Kong Z, Xu X, Yun X, Chao J, Ding D, Li T, Gao Y, Guan N, Zhu C, Qin X
Journal of Cancer 2021;12(7):1926-1935
Journal of Cancer 2021;12(7):1926-1935
Overexpression of TC2N is associated with poor prognosis in gastric cancer.
Xu J, Ou X, Li J, Cai Q, Sun K, Ye J, Peng J
Journal of Cancer 2021;12(3):807-817
Journal of Cancer 2021;12(3):807-817
Nogo-B receptor is required for stabilizing TGF-β type I receptor and promotes the TGF-β1-induced epithelial-to-mesenchymal transition of non-small cell lung cancer.
Wu D, Zhao B, Song Y, Chi X, Fu H, Guan T, Zhang L, Yang X, Hu K, Huang R, Jin X, Miao QR, Shao S
Journal of Cancer 2021;12(3):717-725
Journal of Cancer 2021;12(3):717-725
A Mixture of Baicalein, Wogonin, and Oroxylin-A Inhibits EMT in the A549 Cell Line via the PI3K/AKT-TWIST1-Glycolysis Pathway.
Cao HJ, Zhou W, Xian XL, Sun SJ, Ding PJ, Tian CY, Tian FL, Jiang CH, Fu TT, Zhao S, Dai JY
Frontiers in pharmacology 2021;12:821485
Frontiers in pharmacology 2021;12:821485
Neutralizing Antibodies and Cellular Immune Responses Against SARS-CoV-2 Sustained One and a Half Years After Natural Infection.
Yan LN, Liu PP, Li XG, Zhou SJ, Li H, Wang ZY, Shen F, Lu BC, Long Y, Xiao X, Wang ZD, Li D, Han HJ, Yu H, Zhou SH, Lv WL, Yu XJ
Frontiers in microbiology 2021;12:803031
Frontiers in microbiology 2021;12:803031
Duck Plague Virus pUL48 Protein Activates the Immediate-Early Gene to Initiate the Transcription of the Virus Gene.
Zhou T, Fan D, Wang M, Cheng A, Wu Y, Yang Q, Tian B, Jia R, Ou X, Mao S, Sun D, Zhang S, Zhu D, Chen S, Liu M, Zhao XX, Huang J, Gao Q, Yu Y, Zhang L
Frontiers in microbiology 2021;12:795730
Frontiers in microbiology 2021;12:795730
Activation of α7nAChR Protects Against Gastric Inflammation and Dysmotility in Parkinson's Disease Rats.
Zhou L, Zheng LF, Zhang XL, Wang ZY, Yao YS, Xiu XL, Liu CZ, Zhang Y, Feng XY, Zhu JX
Frontiers in pharmacology 2021;12:793374
Frontiers in pharmacology 2021;12:793374
Resolvin D1 attenuates CCl4 Induced Liver Fibrosis by Inhibiting Autophagy-Mediated HSC activation via AKT/mTOR Pathway.
Li J, Deng X, Wang S, Jiang Q, Xu K
Frontiers in pharmacology 2021;12:792414
Frontiers in pharmacology 2021;12:792414
Punicalin Attenuates Breast Cancer-Associated Osteolysis by Inhibiting the NF-κB Signaling Pathway of Osteoclasts.
Li T, Jiang G, Hu X, Yang D, Tan T, Gao Z, Chen Z, Xiang C, Li S, Ouyang Z, Guo X
Frontiers in pharmacology 2021;12:789552
Frontiers in pharmacology 2021;12:789552
Sorafenib-Induced Autophagy Promotes Glycolysis by Upregulating the p62/HDAC6/HSP90 Axis in Hepatocellular Carcinoma Cells.
Yan X, Tian R, Sun J, Zhao Y, Liu B, Su J, Li M, Sun W, Xu X
Frontiers in pharmacology 2021;12:788667
Frontiers in pharmacology 2021;12:788667
Menthol Targeting AMPK Alleviates the Inflammatory Response of Bovine Mammary Epithelial Cells and Restores the Synthesis of Milk Fat and Milk Protein.
Liu S, Guo W, Jia Y, Ye B, Liu S, Fu S, Liu J, Hu G
Frontiers in immunology 2021;12:782989
Frontiers in immunology 2021;12:782989
Comprehensive Analysis of the Tumor Microenvironment and Ferroptosis-Related Genes Predict Prognosis with Ovarian Cancer.
Li XX, Xiong L, Wen Y, Zhang ZJ
Frontiers in genetics 2021;12:774400
Frontiers in genetics 2021;12:774400
Geniposide Ameliorates Liver Fibrosis Through Reducing Oxidative Stress and Inflammatory Respose, Inhibiting Apoptosis and Modulating Overall Metabolism.
Yang L, Bi L, Jin L, Wang Y, Li Y, Li Z, He W, Cui H, Miao J, Wang L
Frontiers in pharmacology 2021;12:772635
Frontiers in pharmacology 2021;12:772635
The Panda-Derived Lactobacillus plantarum G201683 Alleviates the Inflammatory Response in DSS-Induced Panda Microbiota-Associated Mice.
Zhou Y, Duan L, Zeng Y, Niu L, Pu Y, Jacobs JP, Chang C, Wang J, Khalique A, Pan K, Fang J, Jing B, Zeng D, Ni X
Frontiers in immunology 2021;12:747045
Frontiers in immunology 2021;12:747045
Riclinoctaose Attenuates Renal Ischemia-Reperfusion Injury by the Regulation of Macrophage Polarization.
Zhao Y, Ding Z, Ge W, Liu J, Xu X, Cheng R, Zhang J
Frontiers in pharmacology 2021;12:745425
Frontiers in pharmacology 2021;12:745425
Transcriptomic Profiling Reveals the Antiapoptosis and Antioxidant Stress Effects of Fos in Ischemic Stroke.
Mu Q, Zhang Y, Gu L, Gerner ST, Qiu X, Tao Q, Pang J, Dipritu G, Zhang L, Yin S, Jiang Y, Peng J
Frontiers in neurology 2021;12:728984
Frontiers in neurology 2021;12:728984
Brd4 Regulates the Homeostasis of CD8(+) T-Lymphocytes and Their Proliferation in Response to Antigen Stimulation.
Peng Z, Zhang Y, Ma X, Zhou M, Wu S, Song Z, Yuan Y, Chen Y, Li Y, Wang G, Huang F, Qiao Y, Xia B, Liu W, Liu J, Zhang X, He X, Pan T, Xu H, Zhang H
Frontiers in immunology 2021;12:728082
Frontiers in immunology 2021;12:728082
Hepatic Ischemia-Reperfusion Impairs Blood-Brain Barrier Partly Due to Release of Arginase From Injured Liver.
Zhu L, Zhou H, Xu F, Yang H, Li P, Sheng Y, Liu P, Kong W, Liu X, Yang L, Liu L, Liu X
Frontiers in pharmacology 2021;12:724471
Frontiers in pharmacology 2021;12:724471
Targeting Wnt Signaling in the Tumor Immune Microenvironment to Enhancing EpCAM CAR T-Cell therapy.
Li W, Zhou Y, Wu Z, Shi Y, Tian E, Zhu Y, Wang T, Dou W, Meng X, Chen M, Zhai B, Zhu D
Frontiers in pharmacology 2021;12:724306
Frontiers in pharmacology 2021;12:724306
The Abscopal Effects of Cranial Irradiation Induce Testicular Damage in Mice.
Guo L, Qin TZ, Liu LY, Lai PP, Xue YZ, Jing YT, Zhang W, Li W, Li J, Ding GR
Frontiers in physiology 2021;12:717571
Frontiers in physiology 2021;12:717571
Internal Disulfide Bonding and Glycosylation of Interleukin-7 Protect Against Proteolytic Inactivation by Neutrophil Metalloproteinases and Serine Proteases.
Vandooren J, Pereira RVS, Ugarte-Berzal E, Rybakin V, Noppen S, Stas MR, Bernaerts E, Ganseman E, Metzemaekers M, Schols D, Proost P, Opdenakker G
Frontiers in immunology 2021;12:701739
Frontiers in immunology 2021;12:701739
DHAV-1 Blocks the Signaling Pathway Upstream of Type I Interferon by Inhibiting the Interferon Regulatory Factor 7 Protein.
Lai Y, Xia X, Cheng A, Wang M, Ou X, Mao S, Sun D, Zhang S, Yang Q, Wu Y, Zhu D, Jia R, Chen S, Liu M, Zhao XX, Huang J, Gao Q, Tian B, Liu Y, Yu Y, Zhang L, Pan L
Frontiers in microbiology 2021;12:700434
Frontiers in microbiology 2021;12:700434
Chlorogenic Acid Improves NAFLD by Regulating gut Microbiota and GLP-1.
Shi A, Li T, Zheng Y, Song Y, Wang H, Wang N, Dong L, Shi H
Frontiers in pharmacology 2021;12:693048
Frontiers in pharmacology 2021;12:693048
Lidocaine Promoted Ferroptosis by Targeting miR-382-5p /SLC7A11 Axis in Ovarian and Breast Cancer.
Sun D, Li YC, Zhang XY
Frontiers in pharmacology 2021;12:681223
Frontiers in pharmacology 2021;12:681223
Sinapic Acid Reduces Oxidative Stress and Pyroptosis via Inhibition of BRD4 in Alcoholic Liver Disease.
Chu J, Yan R, Wang S, Li G, Kang X, Hu Y, Lin M, Shan W, Zhao Y, Wang Z, Sun R, Yao J, Zhang N
Frontiers in pharmacology 2021;12:668708
Frontiers in pharmacology 2021;12:668708
The Protective Effects of Sulforaphane on High-Fat Diet-Induced Obesity in Mice Through Browning of White Fat.
Liu Y, Fu X, Chen Z, Luo T, Zhu C, Ji Y, Bian Z
Frontiers in pharmacology 2021;12:665894
Frontiers in pharmacology 2021;12:665894
Yi-Qi-Jian-Pi Formula Suppresses RIPK1/RIPK3-Complex-Dependent Necroptosis of Hepatocytes Through ROS Signaling and Attenuates Liver Injury in Vivo and in Vitro.
Wang F, Tang L, Liang B, Jin C, Gao L, Li Y, Li Z, Shao J, Zhang Z, Tan S, Zhang F, Zheng S
Frontiers in pharmacology 2021;12:658811
Frontiers in pharmacology 2021;12:658811
Neuroprotective Effects of Oxymatrine on PI3K/Akt/mTOR Pathway After Hypoxic-Ischemic Brain Damage in Neonatal Rats.
Wei W, Lu M, Lan XB, Liu N, Su WK, Dushkin AV, Yu JQ
Frontiers in pharmacology 2021;12:642415
Frontiers in pharmacology 2021;12:642415
Chronic Intermittent Hypobaric Hypoxia Decreases High Blood Pressure by Stabilizing the Vascular Renin-Angiotensin System in Spontaneously Hypertensive Rats.
Chen H, Yu B, Guo X, Hua H, Cui F, Guan Y, Tian Y, Zhang X, Zhang Y, Ma H
Frontiers in physiology 2021;12:639454
Frontiers in physiology 2021;12:639454
Isovitexin Inhibits Ginkgolic Acids-Induced Inflammation Through Downregulating SHP2 Activation.
Zhang Y, Qi Z, Wang W, Wang L, Cao F, Zhao L, Fang X
Frontiers in pharmacology 2021;12:630320
Frontiers in pharmacology 2021;12:630320
SNAPIN Regulates Cell Cycle Progression to Promote Pancreatic β Cell Growth.
Jiang M, Kuang Z, He Y, Cao Y, Yu T, Cheng J, Liu W, Wang W
Frontiers in endocrinology 2021;12:624309
Frontiers in endocrinology 2021;12:624309
FLI1 Induces Megakaryopoiesis Gene Expression Through WAS/WIP-Dependent and Independent Mechanisms; Implications for Wiskott-Aldrich Syndrome.
Wang C, Sample KM, Gajendran B, Kapranov P, Liu W, Hu A, Zacksenhaus E, Li Y, Hao X, Ben-David Y
Frontiers in immunology 2021;12:607836
Frontiers in immunology 2021;12:607836
Histone demethylase JMJD3 protects against renal fibrosis by suppressing TGFβ and Notch signaling and preserving PTEN expression.
Yu C, Xiong C, Tang J, Hou X, Liu N, Bayliss G, Zhuang S
Theranostics 2021;11(6):2706-2721
Theranostics 2021;11(6):2706-2721
KDM6A promotes imatinib resistance through YY1-mediated transcriptional upregulation of TRKA independently of its demethylase activity in chronic myelogenous leukemia.
Zhang C, Shen L, Zhu Y, Xu R, Deng Z, Liu X, Ding Y, Wang C, Shi Y, Bei L, Wei D, Thorne RF, Zhang XD, Yu L, Chen S
Theranostics 2021;11(6):2691-2705
Theranostics 2021;11(6):2691-2705
Suppressing Sart1 to modulate macrophage polarization by siRNA-loaded liposomes: a promising therapeutic strategy for pulmonary fibrosis.
Pan T, Zhou Q, Miao K, Zhang L, Wu G, Yu J, Xu Y, Xiong W, Li Y, Wang Y
Theranostics 2021;11(3):1192-1206
Theranostics 2021;11(3):1192-1206
ACSS3 represses prostate cancer progression through downregulating lipid droplet-associated protein PLIN3.
Zhou L, Song Z, Hu J, Liu L, Hou Y, Zhang X, Yang X, Chen K
Theranostics 2021;11(2):841-860
Theranostics 2021;11(2):841-860
Growth hormone receptor disrupts glucose homeostasis via promoting and stabilizing retinol binding protein 4.
Liu J, Nie C, Xue L, Yan Y, Liu S, Sun J, Fan M, Qian H, Ying H, Wang L, Li Y
Theranostics 2021;11(17):8283-8300
Theranostics 2021;11(17):8283-8300
Bioengineering CXCR4-overexpressing cell membrane functionalized ROS-responsive nanotherapeutics for targeting cerebral ischemia-reperfusion injury.
Luo L, Zang G, Liu B, Qin X, Zhang Y, Chen Y, Zhang H, Wu W, Wang G
Theranostics 2021;11(16):8043-8056
Theranostics 2021;11(16):8043-8056
Deciphering the autophagy regulatory network via single-cell transcriptome analysis reveals a requirement for autophagy homeostasis in spermatogenesis.
Wang M, Xu Y, Zhang Y, Chen Y, Chang G, An G, Yang X, Zheng C, Zhao J, Liu Z, Wang D, Miao K, Rao S, Dai M, Wang D, Zhao XY
Theranostics 2021;11(10):5010-5027
Theranostics 2021;11(10):5010-5027
Epigenetically silenced linc00261 contributes to the metastasis of hepatocellular carcinoma via inducing the deficiency of FOXA2 transcription.
Chen Z, Xiang L, Hu Z, Ou H, Liu X, Yu L, Chen W, Jiang L, Yu Q, Fang Y, Xu Y, Liu Q, Huang Y, Li X, Yang D
American journal of cancer research 2021;11(1):277-296
American journal of cancer research 2021;11(1):277-296
Glia Maturation Factor Beta as a Novel Biomarker and Therapeutic Target for Hepatocellular Carcinoma.
Sun W, Hu C, Wang T, Wang J, Zhang J, Gao F, Ou Q, Tian H, Jin C, Xu J, Zhang J, Xu GT, Lu L
Frontiers in oncology 2021;11:744331
Frontiers in oncology 2021;11:744331
circRPS16 Promotes Proliferation and Invasion of Hepatocellular Carcinoma by Sponging miR-876-5p to Upregulate SPINK1.
Lin S, Lin Y, Wu Z, Xia W, Miao C, Peng T, Zhao Z, Ji C, Mo Z, Liu X, Jian Z
Frontiers in oncology 2021;11:724415
Frontiers in oncology 2021;11:724415
CircFAM114A2 Promotes Cisplatin Sensitivity via miR-222-3p/P27 and miR-146a-5p/P21 Cascades in Urothelial Carcinoma.
Lv J, Zhou Z, Wang J, Yang X, Yu H, Han J, Feng D, Yuan B, Wu Q, Li P, Lu Q, Yang H
Frontiers in oncology 2021;11:659166
Frontiers in oncology 2021;11:659166
Calcium Channel Protein ORAI1 Mediates TGF-β Induced Epithelial-to-Mesenchymal Transition in Colorectal Cancer Cells.
Kang Q, Peng X, Li X, Hu D, Wen G, Wei Z, Yuan B
Frontiers in oncology 2021;11:649476
Frontiers in oncology 2021;11:649476
Yap1-2 Isoform Is the Primary Mediator in TGF-β1 Induced EMT in Pancreatic Cancer.
Gao C, Quan MY, Chen QJ, Yang R, Wu Y, Liu JY, Lin ZY, Li X, Cai JT, Jiang TF, Xu L, Mossahebi-Mohammadi M, Guo Q, Zhang JS
Frontiers in oncology 2021;11:649290
Frontiers in oncology 2021;11:649290
Subunit Vaccine ESAT-6:c-di-AMP Delivered by Intranasal Route Elicits Immune Responses and Protects Against Mycobacterium tuberculosis Infection.
Ning H, Zhang W, Kang J, Ding T, Liang X, Lu Y, Guo C, Sun W, Wang H, Bai Y, Shen L
Frontiers in cellular and infection microbiology 2021;11:647220
Frontiers in cellular and infection microbiology 2021;11:647220
The Anti-Inflammatory Effect and Mucosal Barrier Protection of Clostridium butyricum RH2 in Ceftriaxone-Induced Intestinal Dysbacteriosis.
Li Y, Liu M, Liu H, Sui X, Liu Y, Wei X, Liu C, Cheng Y, Ye W, Gao B, Wang X, Lu Q, Cheng H, Zhang L, Yuan J, Li M
Frontiers in cellular and infection microbiology 2021;11:647048
Frontiers in cellular and infection microbiology 2021;11:647048
PTIP Inhibits Cell Invasion in Esophageal Squamous Cell Carcinoma via Modulation of EphA2 Expression.
Han X, Zhu Y, Shen L, Zhou Y, Pang L, Zhou W, Gu H, Han K, Yang Y, Jiang C, Xie J, Zhang C, Ding L
Frontiers in oncology 2021;11:629916
Frontiers in oncology 2021;11:629916
Inhibition of selenoprotein synthesis by Zika virus may contribute to congenital Zika syndrome and microcephaly by mimicking SELENOP knockout and the genetic disease PCCA.
Dailey GP, Premadasa LS, Ruzicka JA, Taylor EW
BBA advances 2021;1
BBA advances 2021;1
Study on the effect of sevoflurane on the cognitive function of aged rats based on the activation of cortical microglia.
Zhou JJ, Zhang C, Yang XX, Zhang XX, Zhang NX, Fang X, Zhu YH, Liu DX, Xu S, Xu MQ, Zhu ZQ
Ibrain 2021 Winter;7(4):288-297
Ibrain 2021 Winter;7(4):288-297
Curcumol inhibits ferritinophagy to restrain hepatocyte senescence through YAP/NCOA4 in non-alcoholic fatty liver disease.
Qi X, Song A, Ma M, Wang P, Zhang X, Lu C, Zhang J, Zheng S, Jin H
Cell proliferation 2021 Sep;54(9):e13107
Cell proliferation 2021 Sep;54(9):e13107
Toxicity evaluation of mesoporous silica particles Santa Barbara No. 15 amorphous in human umbilical vein endothelial cells: influence of particle morphology.
Teng W, Yang Z, Wang S, Xiong D, Chen Y, Wu Z
Journal of applied toxicology : JAT 2021 Sep;41(9):1467-1478
Journal of applied toxicology : JAT 2021 Sep;41(9):1467-1478
Remarkable inhibition effects of afatinib alone or combining with paclitaxel in esophageal squamous cell carcinoma.
Yang LY, Cheng ZJ, Liu Z, Wang D, Zhang N, Fan ZL, Cai HQ, Zhang Y, Cai Y, Xu X, Wang JH, Du GH, Hao JJ, Wang MR
Journal of gastroenterology and hepatology 2021 Sep;36(9):2513-2522
Journal of gastroenterology and hepatology 2021 Sep;36(9):2513-2522
Endogenous reverse transcriptase and RNase H-mediated antiviral mechanism in embryonic stem cells.
Wu J, Wu C, Xing F, Cao L, Zeng W, Guo L, Li P, Zhong Y, Jiang H, Luo M, Shi G, Bu L, Ji Y, Hou P, Peng H, Huang J, Li C, Guo D
Cell research 2021 Sep;31(9):998-1010
Cell research 2021 Sep;31(9):998-1010
TBC1 domain family member 23 interacts with Ras-related protein Rab-11A to promote poor prognosis of non-small-cell lung cancer via β1-integrin.
Zhang Y, Su H, Wudu M, Ren H, Xu Y, Zhang Q, Jiang J, Wang Q, Jiang X, Zhang B, Liu Z, Zou Z, Qiu X
Journal of cellular and molecular medicine 2021 Sep;25(18):8821-8835
Journal of cellular and molecular medicine 2021 Sep;25(18):8821-8835
Salusin‑β participates in high glucose‑induced HK‑2 cell ferroptosis in a Nrf‑2‑dependent manner.
Wang WJ, Jiang X, Gao CC, Chen ZW
Molecular medicine reports 2021 Sep;24(3)
Molecular medicine reports 2021 Sep;24(3)
Mitochondrial calcium uniporter promotes cell proliferation and migration in esophageal cancer.
Miao Y, Wang X, Lai Y, Lin W, Huang Y, Yin H, Hou R, Zhang F
Oncology letters 2021 Sep;22(3):686
Oncology letters 2021 Sep;22(3):686
Protein arginine methyltransferase 5 mediates THP-1-derived macrophage activation dependent on NF-κB in endometriosis.
Chai X, Wu X, He L, Ding H
Experimental and therapeutic medicine 2021 Sep;22(3):1003
Experimental and therapeutic medicine 2021 Sep;22(3):1003
Treadmill exercise alleviates neuronal damage by suppressing NLRP3 inflammasome and microglial activation in the MPTP mouse model of Parkinson's disease.
Wang W, Lv Z, Gao J, Liu M, Wang Y, Tang C, Xiang J
Brain research bulletin 2021 Sep;174:349-358
Brain research bulletin 2021 Sep;174:349-358
Magnesium-L-threonate alleviate colonic inflammation and memory impairment in chronic-plus-binge alcohol feeding mice.
Liu C, Cheng Y, Guo Y, Qian H
Brain research bulletin 2021 Sep;174:184-193
Brain research bulletin 2021 Sep;174:184-193
Probiotic fermentation of Ganoderma lucidum fruiting body extracts promoted its immunostimulatory activity in mice with dexamethasone-induced immunosuppression.
Li Y, Liu H, Qi H, Tang W, Zhang C, Liu Z, Liu Y, Wei X, Kong Z, Jia S, Du B, Yuan J, Wang C, Li M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Sep;141:111909
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Sep;141:111909
Blockade of GITRL/GITR signaling pathway attenuates house dust mite-induced allergic asthma in mice through inhibition of MAPKs and NF-κB signaling.
Wang Y, Liu B, Niu C, Zou W, Yang L, Wang T, Tian D, Luo Z, Dai J, Li Q, Liu E, Gong C, Fu Z, Ding F
Molecular immunology 2021 Sep;137:238-246
Molecular immunology 2021 Sep;137:238-246
A methylation-driven gene panel predicts survival in patients with colon cancer.
Peng Y, Zhao J, Yin F, Sharen G, Wu Q, Chen Q, Sun X, Yang J, Wang H, Zhang D
FEBS open bio 2021 Sep;11(9):2490-2506
FEBS open bio 2021 Sep;11(9):2490-2506
Aloe-emodin prevents nerve injury and neuroinflammation caused by ischemic stroke via the PI3K/AKT/mTOR and NF-κB pathway.
Xian M, Cai J, Zheng K, Liu Q, Liu Y, Lin H, Liang S, Wang S
Food & function 2021 Sep 7;12(17):8056-8067
Food & function 2021 Sep 7;12(17):8056-8067
Microglia-derived IL-1β promoted neuronal apoptosis through ER stress-mediated signaling pathway PERK/eIF2α/ATF4/CHOP upon arsenic exposure.
Liu X, Chen Y, Wang H, Wei Y, Yuan Y, Zhou Q, Fang F, Shi S, Jiang X, Dong Y, Li X
Journal of hazardous materials 2021 Sep 5;417:125997
Journal of hazardous materials 2021 Sep 5;417:125997
Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes.
Scheiblich H, Dansokho C, Mercan D, Schmidt SV, Bousset L, Wischhof L, Eikens F, Odainic A, Spitzer J, Griep A, Schwartz S, Bano D, Latz E, Melki R, Heneka MT
Cell 2021 Sep 30;184(20):5089-5106.e21
Cell 2021 Sep 30;184(20):5089-5106.e21
LncRNA ZNFTR functions as an inhibitor in pancreatic cancer by modulating ATF3/ZNF24/VEGFA pathway.
Li W, Han S, Hu P, Chen D, Zeng Z, Hu Y, Xu F, Tang J, Wang F, Zhao Y, Huang M, Zhao G
Cell death & disease 2021 Sep 3;12(9):830
Cell death & disease 2021 Sep 3;12(9):830
3'HS1 CTCF binding site in human β-globin locus regulates fetal hemoglobin expression.
Himadewi P, Wang XQD, Feng F, Gore H, Liu Y, Yu L, Kurita R, Nakamura Y, Pfeifer GP, Liu J, Zhang X
eLife 2021 Sep 29;10
eLife 2021 Sep 29;10
JaponiconeA induces apoptosis of bortezomib-sensitive and -resistant myeloma cells in vitro and in vivo by targeting IKK.
Zhang Z, Ye C, Liu J, Xu W, Wu C, Yu Q, Xu X, Zeng X, Jin H, Wu Y, Yan H
Cancer biology & medicine 2021 Sep 28;19(5):651-68
Cancer biology & medicine 2021 Sep 28;19(5):651-68
Sodium Tanshinone IIA Sulfonate Attenuates Cigarette Smoke Extract-Induced Mitochondrial Dysfunction, Oxidative Stress, and Apoptosis in Alveolar Epithelial Cells by Enhancing SIRT1 Pathway.
Guan R, Yao H, Li Z, Qian J, Yuan L, Cai Z, Ding M, Liu W, Xu J, Li Y, Sun D, Wang J, Lu W
Toxicological sciences : an official journal of the Society of Toxicology 2021 Sep 28;183(2):352-362
Toxicological sciences : an official journal of the Society of Toxicology 2021 Sep 28;183(2):352-362
Nano chitosan-zinc complex improves the growth performance and antioxidant capacity of the small intestine in weaned piglets.
Zhang M, Hou G, Hu P, Feng D, Wang J, Zhu W
The British journal of nutrition 2021 Sep 28;126(6):801-812
The British journal of nutrition 2021 Sep 28;126(6):801-812
Different concentrations of C5a affect human dental pulp mesenchymal stem cells differentiation.
Liu J, Wei X, Hu J, Tan X, Kang X, Gao L, Li N, Shi X, Yuan M, Hu W, Liu M
BMC oral health 2021 Sep 24;21(1):470
BMC oral health 2021 Sep 24;21(1):470
Proteomics identifies a novel role of fibrinogen-like protein 1 in Crohn's disease.
Sun XL, Qiao LC, Gong J, Wen K, Xu ZZ, Yang BL
World journal of gastroenterology 2021 Sep 21;27(35):5946-5957
World journal of gastroenterology 2021 Sep 21;27(35):5946-5957
Mechanistic study of lncRNA UCA1 promoting growth and cisplatin resistance in lung adenocarcinoma.
Fu J, Pan J, Yang X, Zhang Y, Shao F, Chen J, Huang K, Wang Y
Cancer cell international 2021 Sep 20;21(1):505
Cancer cell international 2021 Sep 20;21(1):505
Structural Studies of Water-Insoluble β-Glucan from Oat Bran and Its Effect on Improving Lipid Metabolism in Mice Fed High-Fat Diet.
Yu S, Wang J, Li Y, Wang X, Ren F, Wang X
Nutrients 2021 Sep 18;13(9)
Nutrients 2021 Sep 18;13(9)
Aged Ripe Pu-erh Tea Reduced Oxidative Stress-Mediated Inflammation in Dextran Sulfate Sodium-Induced Colitis Mice by Regulating Intestinal Microbes.
Hu S, Li S, Liu Y, Sun K, Luo L, Zeng L
Journal of agricultural and food chemistry 2021 Sep 15;69(36):10592-10605
Journal of agricultural and food chemistry 2021 Sep 15;69(36):10592-10605
Reduced DAPK1 Expression Promotes Stem Cell-Like Characteristics of Prostate Cancer Cells by Activating ZEB1 via Hippo/YAP Signaling Pathway.
Nong S, Wei Z, Wang Z, Ma L, Guan Y, Ni J
Stem cells and development 2021 Sep 15;30(18):934-945
Stem cells and development 2021 Sep 15;30(18):934-945
Raf1 interacts with OIP5 to participate in oxaliplatin-induced neuropathic pain.
Yu W, Zheng Z, Wei W, Li L, Zhang Y, Sun Y, Cao J, Zang W, Shao J
Life sciences 2021 Sep 15;281:119804
Life sciences 2021 Sep 15;281:119804
Abnormal spatiotemporal expression pattern of progranulin and neurodevelopment impairment in VPA-induced ASD rat model.
Lan J, Hu Y, Wang X, Zheng W, Liao A, Wang S, Li Y, Wang Y, Yang F, Chen D
Neuropharmacology 2021 Sep 15;196:108689
Neuropharmacology 2021 Sep 15;196:108689
Effect of different exercise training intensities on age-related cardiac damage in male mice.
Pei Z, Yang C, Guo Y, Dong M, Wang F
Aging 2021 Sep 14;13(17):21700-21711
Aging 2021 Sep 14;13(17):21700-21711
Nintedanib Regulates GRK2 and CXCR2 to Reduce Neutrophil Recruitment in Endotoxin-Induced Lung Injury.
Su VY, Chen WC, Yu WK, Wu HH, Chen H, Yang KY
International journal of molecular sciences 2021 Sep 13;22(18)
International journal of molecular sciences 2021 Sep 13;22(18)
Betulinic acid induces autophagy-dependent apoptosis via Bmi-1/ROS/AMPK-mTOR-ULK1 axis in human bladder cancer cells.
Zhang Y, He N, Zhou X, Wang F, Cai H, Huang SH, Chen X, Hu Z, Jin X
Aging 2021 Sep 12;13(17):21251-21267
Aging 2021 Sep 12;13(17):21251-21267
MicroRNA-30c-5p protects against myocardial ischemia/reperfusion injury via regulation of Bach1/Nrf2.
Sun M, Guo M, Ma G, Zhang N, Pan F, Fan X, Wang R
Toxicology and applied pharmacology 2021 Sep 1;426:115637
Toxicology and applied pharmacology 2021 Sep 1;426:115637
Analysis of the microRNA and mRNA expression profile of ricin toxin-treated RAW264.7 cells reveals that miR-155-3p suppresses cell inflammation by targeting GAB2.
Liu Z, Zhang X, Dong M, Liu Z, Wang Y, Yu H, Yu K, Xu N, Liu W, Song H
Toxicology letters 2021 Sep 1;347:67-77
Toxicology letters 2021 Sep 1;347:67-77
Resveratrol-mediated neurorestoration after cerebral ischemic injury - Sonic Hedgehog signaling pathway.
Yu P, Wang L, Tang F, Guo S, Liao H, Fan C, Yang Q
Life sciences 2021 Sep 1;280:119715
Life sciences 2021 Sep 1;280:119715
Phenotypic differences in the inner ears of CBA/CaJ and C57BL/6J mice carrying missense and single base pair deletion mutations in the Cdh23 gene.
Zhao T, Ma P, Zhao F, Zheng T, Yan B, Zhang Q, Yuan J, Hu B, Yang Y, Hu J, Geng R, Hu BH, Sun T, Zheng QY, Li B
Journal of neuroscience research 2021 Oct;99(10):2743-2758
Journal of neuroscience research 2021 Oct;99(10):2743-2758
Activation of CB2 receptor inhibits pyroptosis and subsequently ameliorates cecal ligation and puncture-induced sepsis.
Zhang B, Zheng F, Liu A, Li Z, Zheng F, Liu Q, Yang L, Chen K, Wang Y, Zhang Z, He Q, Zhan J
International immunopharmacology 2021 Oct;99:108038
International immunopharmacology 2021 Oct;99:108038
Inhibition of TNFAIP1 ameliorates the oxidative stress and inflammatory injury in myocardial ischemia/reperfusion injury through modulation of Akt/GSK-3β/Nrf2 pathway.
Wen L, Yang QH, Ma XL, Li T, Xiao S, Sun CF
International immunopharmacology 2021 Oct;99:107993
International immunopharmacology 2021 Oct;99:107993
Long-term in-vitro glucocorticoid treatment induces glucocorticoid resistance in canine mast cell tumors.
Matsuda A
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire 2021 Oct;85(4):302-308
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire 2021 Oct;85(4):302-308
Astrocyte-selective STAT3 knockdown rescues methamphetamine withdrawal-disrupted spatial memory in mice via restoring the astrocytic capacity of glutamate clearance in dCA1.
Shi P, Li Z, He T, Li N, Xu X, Yu P, Lu X, Nie J, Liu D, Cai Q, Guan Y, Ge F, Wang J, Guan X
Glia 2021 Oct;69(10):2404-2418
Glia 2021 Oct;69(10):2404-2418
Inhibition of ER stress attenuates kidney injury and apoptosis induced by 3-MCPD via regulating mitochondrial fission/fusion and Ca(2+) homeostasis.
Zhong Y, Jin C, Han J, Zhu J, Liu Q, Sun D, Xia X, Peng X
Cell biology and toxicology 2021 Oct;37(5):795-809
Cell biology and toxicology 2021 Oct;37(5):795-809
The long non-coding RNA PFI protects against pulmonary fibrosis by interacting with splicing regulator SRSF1.
Sun J, Jin T, Su W, Guo Y, Niu Z, Guo J, Li L, Wang J, Ma L, Yu T, Li X, Zhou Y, Shan H, Liang H
Cell death and differentiation 2021 Oct;28(10):2916-2930
Cell death and differentiation 2021 Oct;28(10):2916-2930
Exosomes derived from idiopathic gingival fibroma fibroblasts regulate gingival fibroblast proliferation and apoptosis.
Yin S, Jia F, Ran L, Xie L, Wu Z, Zhan Y, Zhang Y, Zhang M
Oral diseases 2021 Oct;27(7):1789-1795
Oral diseases 2021 Oct;27(7):1789-1795
Arsenic Trioxide Combining Leflunomide Activates Nrf2-ARE-HO-1 Signaling Pathway and Protects Heart Xenografts.
Wang TD, Xu SL, Yu ZY, Ni SB, Zhang C, Jiao ZX
Chinese journal of integrative medicine 2021 Oct;27(10):760-766
Chinese journal of integrative medicine 2021 Oct;27(10):760-766
Sepsis induces muscle atrophy by inhibiting proliferation and promoting apoptosis via PLK1-AKT signalling.
Cao YY, Wang Z, Yu T, Zhang Y, Wang ZH, Lu ZM, Lu WH, Yu JB
Journal of cellular and molecular medicine 2021 Oct;25(20):9724-9739
Journal of cellular and molecular medicine 2021 Oct;25(20):9724-9739
Human umbilical cord mesenchymal stem cells ameliorate depression by regulating Jmjd3 and microglia polarization in myocardial infarction mice.
Zhang Y, Wang X, Li Y, Liu R, Pan J, Tang X, Sun S, Liu J, Ma W
Psychopharmacology 2021 Oct;238(10):2973-2984
Psychopharmacology 2021 Oct;238(10):2973-2984
Dihydroartemisinin suppresses proliferation, migration, the Wnt/β-catenin pathway and EMT via TNKS in gastric cancer.
Ma Y, Zhang P, Zhang Q, Wang X, Miao Q, Lyu X, Cui B, Ma H
Oncology letters 2021 Oct;22(4):688
Oncology letters 2021 Oct;22(4):688
The role of alcohol dehydrogenase 1C in regulating inflammatory responses in ulcerative colitis.
Song F, Zhang Y, Pan Z, Hu X, Zhang Q, Huang F, Ye X, Huang P
Biochemical pharmacology 2021 Oct;192:114691
Biochemical pharmacology 2021 Oct;192:114691
Integrating systematic pharmacology-based strategy and experimental validation to explore the synergistic pharmacological mechanisms of Guanxin V in treating ventricular remodeling.
Liang B, Liang Y, Li R, Zhang H, Gu N
Bioorganic chemistry 2021 Oct;115:105187
Bioorganic chemistry 2021 Oct;115:105187
Myosin 1f-mediated activation of microglia contributes to the photoreceptor degeneration in a mouse model of retinal detachment.
Wang Y, Zhao X, Gao M, Wan X, Guo Y, Qu Y, Chen Y, Li T, Liu H, Jiang M, Wang F, Sun X
Cell death & disease 2021 Oct 9;12(10):926
Cell death & disease 2021 Oct 9;12(10):926
Ferrostatin-1 alleviated TNBS induced colitis via the inhibition of ferroptosis.
Xu J, Liu S, Cui Z, Wang X, Ning T, Wang T, Zhang N, Xie S, Min L, Zhang S, Liang C, Zhu S
Biochemical and biophysical research communications 2021 Oct 8;573:48-54
Biochemical and biophysical research communications 2021 Oct 8;573:48-54
EphA2 inhibits SRA01/04 cells apoptosis by suppressing autophagy via activating PI3K/Akt/mTOR pathway.
Han J, Wang L, Lv H, Liu J, Dong Y, Shi L, Ji Q
Archives of biochemistry and biophysics 2021 Oct 30;711:109024
Archives of biochemistry and biophysics 2021 Oct 30;711:109024
UM-6 induces autophagy and apoptosis via the Hippo-YAP signaling pathway in cervical cancer.
Wang D, He J, Dong J, Wu S, Liu S, Zhu H, Xu T
Cancer letters 2021 Oct 28;519:2-19
Cancer letters 2021 Oct 28;519:2-19
ZEB1 represses biogenesis of circ-DOCK5 to facilitate metastasis in esophageal squamous cell carcinoma via a positive feedback loop with TGF-β.
Meng L, Zheng Y, Liu S, Ju Y, Ren S, Sang Y, Zhu Y, Gu L, Liu F, Zhao Y, Zhang X, Sang M
Cancer letters 2021 Oct 28;519:117-129
Cancer letters 2021 Oct 28;519:117-129
RCAN1.4 attenuates renal fibrosis through inhibiting calcineurin-mediated nuclear translocation of NFAT2.
Zhang J, Chen H, Weng X, Liu H, Chen Z, Huang Q, Wang L, Liu X
Cell death discovery 2021 Oct 27;7(1):317
Cell death discovery 2021 Oct 27;7(1):317
Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation.
Ulferts R, Marcassa E, Timimi L, Lee LC, Daley A, Montaner B, Turner SD, Florey O, Baillie JK, Beale R
Cell reports 2021 Oct 26;37(4):109899
Cell reports 2021 Oct 26;37(4):109899
Hypoxic tubular epithelial cells regulate the angiogenesis of HMEC-1 cells via mediation of Rab7/MMP-2 axis.
Yang Y, Wang J, Zhang Y, Hu X, Li L, Chen P
Aging 2021 Oct 25;13(20):23769-23779
Aging 2021 Oct 25;13(20):23769-23779
Berberine Inhibits MDA-MB-231 Cells as an Agonist of G Protein-Coupled Estrogen Receptor 1.
Qi M, Liu X, Zhou Y, Wang H, Zhao Y, Ren J, Xiang J
International journal of molecular sciences 2021 Oct 24;22(21)
International journal of molecular sciences 2021 Oct 24;22(21)
Fructooligosaccharide supplementation alleviated the pathological immune response and prevented the impairment of intestinal barrier in DSS-induced acute colitis mice.
Liao M, Zhang Y, Qiu Y, Wu Z, Zhong Z, Zeng X, Zeng Y, Xiong L, Wen Y, Liu R
Food & function 2021 Oct 19;12(20):9844-9854
Food & function 2021 Oct 19;12(20):9844-9854
Gut microbiota-dependent catabolites of tryptophan play a predominant role in the protective effects of turmeric polysaccharides against DSS-induced ulcerative colitis.
Yang C, Du Y, Ren D, Yang X, Zhao Y
Food & function 2021 Oct 19;12(20):9793-9807
Food & function 2021 Oct 19;12(20):9793-9807
Regulation of survivin protein stability by USP35 is evolutionarily conserved.
Wang W, Lin H, Zheng E, Hou Z, Liu Y, Huang W, Chen D, Feng J, Li J, Li L
Biochemical and biophysical research communications 2021 Oct 15;574:48-55
Biochemical and biophysical research communications 2021 Oct 15;574:48-55
SMAD2 regulates testicular development and testosterone synthesis in Hu sheep.
Yang H, Wan Z, Jin Y, Wang F, Zhang Y
Theriogenology 2021 Oct 15;174:139-148
Theriogenology 2021 Oct 15;174:139-148
METTL3 improves cardiomyocyte proliferation upon myocardial infarction via upregulating miR-17-3p in a DGCR8-dependent manner.
Zhao K, Yang C, Zhang J, Sun W, Zhou B, Kong X, Shi J
Cell death discovery 2021 Oct 13;7(1):291
Cell death discovery 2021 Oct 13;7(1):291
Chorionic villus-derived mesenchymal stem cell-mediated autophagy promotes the proliferation and invasiveness of trophoblasts under hypoxia by activating the JAK2/STAT3 signalling pathway.
Chu Y, Zhu C, Yue C, Peng W, Chen W, He G, Liu C, Lv Y, Gao G, Yao K, Han R, Hu X, Zhang Y, Ye Y
Cell & bioscience 2021 Oct 13;11(1):182
Cell & bioscience 2021 Oct 13;11(1):182
Methamphetamine mediates apoptosis of vascular smooth muscle cells via the chop-related endoplasmic reticulum stress pathway.
Tan X, Cai D, Chen N, Du S, Qiao D, Yue X, Wang T, Li J, Xie W, Wang H
Toxicology letters 2021 Oct 10;350:98-110
Toxicology letters 2021 Oct 10;350:98-110
Exercise Intervention Mitigates Pathological Liver Changes in NAFLD Zebrafish by Activating SIRT1/AMPK/NRF2 Signaling.
Zou Y, Chen Z, Sun C, Yang D, Zhou Z, Peng X, Zheng L, Tang C
International journal of molecular sciences 2021 Oct 10;22(20)
International journal of molecular sciences 2021 Oct 10;22(20)
Effects of cannabinoid (CBD) on blood brain barrier permeability after brain injury in rats.
Jiang H, Li H, Cao Y, Zhang R, Zhou L, Zhou Y, Zeng X, Wu J, Wu D, Wu D, Guo X, Li X, Wu H, Li P
Brain research 2021 Oct 1;1768:147586
Brain research 2021 Oct 1;1768:147586
Melatonin alleviated oxidative stress induced by energy restriction on sheep Leydig cells through Sirt1/Sod2 pathway.
Ma J, Yang H, Liu L, Wan Y, Wang F
Theriogenology 2021 Oct 1;173:83-92
Theriogenology 2021 Oct 1;173:83-92
Vitamin A and retinoic acid accelerate the attenuation of intestinal adaptability upon feeding induced by high-fat diet in mice.
Hong W, Xu D, Song X, Niu B, Zhuang Z, Lu Y, Lei X, Ma R, Lu C, Sun N, Mao Y, Li X
The Journal of nutritional biochemistry 2021 Nov;97:108803
The Journal of nutritional biochemistry 2021 Nov;97:108803
Downregulated fat mass and obesity-associated protein inhibits bone resorption and osteoclastogenesis by nuclear factor-kappa B inactivation.
Zhuang J, Ning H, Wang M, Zhao W, Jing Y, Liu X, Zu J, Kong P, Wang X, Sun C, Yan J
Cellular signalling 2021 Nov;87:110137
Cellular signalling 2021 Nov;87:110137
miR‑4792 regulates inflammatory responses in Cryptococcus neoformans‑infected microglia.
Yao G, Wang X, Wang Y, Hou Q, Gao R, Wang Y, Teng L, Lin W, Wang Z, Jin Y, Chen J
International journal of molecular medicine 2021 Nov;48(5)
International journal of molecular medicine 2021 Nov;48(5)
Ginsenoside Rg1 attenuates mechanical stress-induced cardiac injury via calcium sensing receptor-related pathway.
Lu ML, Wang J, Sun Y, Li C, Sun TR, Hou XW, Wang HX
Journal of ginseng research 2021 Nov;45(6):683-694
Journal of ginseng research 2021 Nov;45(6):683-694
Nicotinamide improves NAD(+) levels to protect against acetaminophen-induced acute liver injury in mice.
Xu J, Zhang L, Jiang R, Hu K, Hu D, Liao C, Jiang S, Yang Y, Huang J, Tang L, Li L
Human & experimental toxicology 2021 Nov;40(11):1938-1946
Human & experimental toxicology 2021 Nov;40(11):1938-1946
Loss of PHLDA1 has a protective role in OGD/R-injured neurons via regulation of the GSK-3β/Nrf2 pathway.
Yang F, Chen R
Human & experimental toxicology 2021 Nov;40(11):1909-1920
Human & experimental toxicology 2021 Nov;40(11):1909-1920
PHLDA3 inhibition protects against myocardial ischemia/reperfusion injury by alleviating oxidative stress and inflammatory response via the Akt/Nrf2 axis.
Meng X, Zhang L, Han B, Zhang Z
Environmental toxicology 2021 Nov;36(11):2266-2277
Environmental toxicology 2021 Nov;36(11):2266-2277
The immunosuppressive role of Edn3 overexpression in the melanoma microenvironment.
Freitas JT, Lopez J, Llorian C, Boroni M, Kos L
Pigment cell & melanoma research 2021 Nov;34(6):1084-1093
Pigment cell & melanoma research 2021 Nov;34(6):1084-1093
Ferroptosis is involved in the anti-tumor effect of lycorine in renal cell carcinoma cells.
Du Y, Zhao HC, Zhu HC, Jin Y, Wang L
Oncology letters 2021 Nov;22(5):781
Oncology letters 2021 Nov;22(5):781
Maiwei Yangfei decoction prevents bleomycin-induced pulmonary fibrosis in mice.
Xu Y, Peng W, Han D, Feng F, Wang Z, Gu C, Zhou X, Wu Q
Experimental and therapeutic medicine 2021 Nov;22(5):1306
Experimental and therapeutic medicine 2021 Nov;22(5):1306
Hypercholesterolemia risk associated Abca6 does not regulate lipoprotein metabolism in mice or hamster.
He B, Kang S, Chen Z, Liu X, Wang J, Li X, Liu X, Zheng L, Luo M, Wang Y
Biochimica et biophysica acta. Molecular and cell biology of lipids 2021 Nov;1866(11):159006
Biochimica et biophysica acta. Molecular and cell biology of lipids 2021 Nov;1866(11):159006
Th17/IL-17 induces endothelial cell senescence via activation of NF-κB/p53/Rb signaling pathway.
Zhang L, Liu M, Liu W, Hu C, Li H, Deng J, Cao Q, Wang Y, Hu W, Li Q
Laboratory investigation; a journal of technical methods and pathology 2021 Nov;101(11):1418-1426
Laboratory investigation; a journal of technical methods and pathology 2021 Nov;101(11):1418-1426
Oxymatrine inhibits neuroinflammation byRegulating M1/M2 polarization in N9 microglia through the TLR4/NF-κB pathway.
Wang XL, Chen F, Shi H, Zhang M, Yan L, Pei XY, Peng XD
International immunopharmacology 2021 Nov;100:108139
International immunopharmacology 2021 Nov;100:108139
Starvation induced autophagy promotes the progression of bladder cancer by LDHA mediated metabolic reprogramming.
Li T, Tong H, Yin H, Luo Y, Zhu J, Qin Z, Yin S, He W
Cancer cell international 2021 Nov 7;21(1):597
Cancer cell international 2021 Nov 7;21(1):597
Dual Hyaluronic Acid and Folic Acid Targeting pH-Sensitive Multifunctional 2DG@DCA@MgO-Nano-Core-Shell-Radiosensitizer for Breast Cancer Therapy.
Askar MA, Thabet NM, El-Sayyad GS, El-Batal AI, Abd Elkodous M, El Shawi OE, Helal H, Abdel-Rafei MK
Cancers 2021 Nov 7;13(21)
Cancers 2021 Nov 7;13(21)
Identification of a Proteomic Signature of Senescence in Primary Human Mammary Epithelial Cells.
Delfarah A, Hartel NG, Zheng D, Yang J, Graham NA
Journal of proteome research 2021 Nov 5;20(11):5169-5179
Journal of proteome research 2021 Nov 5;20(11):5169-5179
Identification of candidate biomarker EMP3 and its prognostic potential in clear cell renal cell carcinoma.
Lv Q, Xiao W, Xiong Z, Shi J, Miao D, Meng X, Yuan H, Yang H, Zhang X
Frontiers in bioscience (Landmark edition) 2021 Nov 30;26(11):1176-1190
Frontiers in bioscience (Landmark edition) 2021 Nov 30;26(11):1176-1190
CircCRIM1 promotes ovarian cancer progression by working as ceRNAs of CRIM1 and targeting miR-383-5p/ZEB2 axis.
Du Y, Liu X, Zhang S, Chen S, Guan X, Li Q, Chen X, Zhao Y
Reproductive biology and endocrinology : RB&E 2021 Nov 30;19(1):176
Reproductive biology and endocrinology : RB&E 2021 Nov 30;19(1):176
SLC25A1 promotes tumor growth and survival by reprogramming energy metabolism in colorectal cancer.
Yang Y, He J, Zhang B, Zhang Z, Jia G, Liu S, Wu T, He X, Wang N
Cell death & disease 2021 Nov 27;12(12):1108
Cell death & disease 2021 Nov 27;12(12):1108
miR-23a/b-3p promotes hepatic lipid accumulation by regulating Srebp-1c and Fas.
Li L, Zhang X, Ren H, Huang X, Shen T, Tang W, Dou L, Li J
Journal of molecular endocrinology 2021 Nov 26;68(1):35-49
Journal of molecular endocrinology 2021 Nov 26;68(1):35-49
Tβ4 ameliorates oxidative damage and apoptosis through ERK/MAPK and 5-HT1A signaling pathway in Aβ insulted SH-SY5Y cells.
Zhang GH, Pare RB, Chin KL, Qian YH
Life sciences 2021 Nov 25;:120178
Life sciences 2021 Nov 25;:120178
Exposure to melamine cyanuric acid in adult mice induced thyroid dysfunction and circadian rhythm disorder.
Wang S, Wang S, Wang C, Feng D, Feng X
Ecotoxicology and environmental safety 2021 Nov 19;228:112992
Ecotoxicology and environmental safety 2021 Nov 19;228:112992
Verapamil ameliorates proximal tubular epithelial cells apoptosis and fibrosis in diabetic kidney.
Song Y, Guo F, Zhao Y, Zhao L, Fan X, Zhang Y, Liu Y, Qin G
European journal of pharmacology 2021 Nov 15;911:174552
European journal of pharmacology 2021 Nov 15;911:174552
Programmed cell death 5 improves skeletal muscle insulin resistance by inhibiting IRS-1 ubiquitination through stabilization of MDM2.
Li B, Ye J, Liu R, Weng L, Cao Y, Jia S, Xu C, Liu Y, Yan S, Zheng M
Life sciences 2021 Nov 15;285:119918
Life sciences 2021 Nov 15;285:119918
TM9SF4 is a novel regulator in lineage commitment of bone marrow mesenchymal stem cells to either osteoblasts or adipocytes.
Yu L, Xie M, Zhang F, Wan C, Yao X
Stem cell research & therapy 2021 Nov 13;12(1):573
Stem cell research & therapy 2021 Nov 13;12(1):573
AP39 ameliorates high fat diet-induced liver injury in young rats via alleviation of oxidative stress and mitochondrial impairment.
Yu Y, Ye SM, Liu DY, Yang LQ
Experimental animals 2021 Nov 10;70(4):553-562
Experimental animals 2021 Nov 10;70(4):553-562
Down-regulation of EPB41L4A-AS1 mediated the brain aging and neurodegenerative diseases via damaging synthesis of NAD(+) and ATP.
Yang T, Wang Y, Liao W, Zhang S, Wang S, Xu N, Xie W, Luo C, Wang Y, Wang Z, Zhang Y
Cell & bioscience 2021 Nov 10;11(1):192
Cell & bioscience 2021 Nov 10;11(1):192
TRIM15 promotes the invasion and metastasis of pancreatic cancer cells by mediating APOA1 ubiquitination and degradation.
Sun Y, Ren D, Yang C, Yang W, Zhao J, Zhou Y, Jin X, Wu H
Biochimica et biophysica acta. Molecular basis of disease 2021 Nov 1;1867(11):166213
Biochimica et biophysica acta. Molecular basis of disease 2021 Nov 1;1867(11):166213
UFL1 regulates milk protein and fat synthesis-related gene expression of bovine mammary epithelial cells probably via the mTOR signaling pathway.
Li C, Li L, Ali I, Kuang M, Wang X, Wang G
In vitro cellular & developmental biology. Animal 2021 May;57(5):550-559
In vitro cellular & developmental biology. Animal 2021 May;57(5):550-559
Lipoxin A4 protects against paraquat‑induced acute lung injury by inhibiting the TLR4/MyD88‑mediated activation of the NF‑κB and PI3K/AKT pathways.
Li Y, Wang N, Ma Z, Wang Y, Yuan Y, Zhong Z, Hong Y, Zhao M
International journal of molecular medicine 2021 May;47(5)
International journal of molecular medicine 2021 May;47(5)
33-kDa ANXA3 isoform contributes to hepatocarcinogenesis via modulating ERK, PI3K/Akt-HIF and intrinsic apoptosis pathways.
Guo C, Li N, Dong C, Wang L, Li Z, Liu Q, Ma Q, Greenaway FT, Tian Y, Hao L, Liu S, Sun MZ
Journal of advanced research 2021 May;30:85-102
Journal of advanced research 2021 May;30:85-102
GDF11 prevents the formation of thoracic aortic dissection in mice: Promotion of contractile transition of aortic SMCs.
Ren K, Li B, Liu Z, Xia L, Zhai M, Wei X, Duan W, Yu S
Journal of cellular and molecular medicine 2021 May;25(10):4623-4636
Journal of cellular and molecular medicine 2021 May;25(10):4623-4636
Extracellular DJ-1 induces sterile inflammation in the ischemic brain.
Nakamura K, Sakai S, Tsuyama J, Nakamura A, Otani K, Kurabayashi K, Yogiashi Y, Masai H, Shichita T
PLoS biology 2021 May;19(5):e3000939
PLoS biology 2021 May;19(5):e3000939
Ubash3b promotes TPA-mediated suppression of leukemogenesis through accelerated downregulation of PKCδ protein.
Yao Y, Liu W, Gajendran B, Wang C, Zacksenhaus E, Sample KM, Varier KM, Hao X, Ben-David Y
Biochimie 2021 May;184:8-17
Biochimie 2021 May;184:8-17
MicroRNA-628-5p Facilitates Enterovirus 71 Infection by Suppressing TRAF3 Signaling.
Li D, Chen S, Zhang W, Zhang C, Sun T, Du Y, Ding R, Gao Y, Jin Y, Duan G
Cellular & molecular immunology 2021 May;18(5):1320-1322
Cellular & molecular immunology 2021 May;18(5):1320-1322
Zinc-α2-glycoprotein relieved seizure-Induced neuronal glucose uptake impairment via insulin-like growth factor 1 receptor-regulated glucose transporter 3 expression.
Peng W, Liu X, Tan C, Zhou W, Jiang J, Zhou X, Du J, Mo L, Chen L
Journal of neurochemistry 2021 May;157(3):695-709
Journal of neurochemistry 2021 May;157(3):695-709
Danthron ameliorates obesity and MAFLD through activating the interplay between PPARα/RXRα heterodimer and adiponectin receptor 2.
Ma C, Wang Z, Xia R, Wei L, Zhang C, Zhang J, Zhao L, Wu H, Kang L, Yang S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 May;137:111344
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 May;137:111344
Human Cytomegalovirus Uses a Host Stress Response To Balance the Elongation of Saturated/Monounsaturated and Polyunsaturated Very-Long-Chain Fatty Acids.
Xi Y, Lindenmayer L, Kline I, von Einem J, Purdy JG
mBio 2021 May 4;12(3)
mBio 2021 May 4;12(3)
Mechanistic insights into the anti-depressant effect of emodin: an integrated systems pharmacology study and experimental validation.
Zeng P, Wang XM, Ye CY, Su HF, Fang YY, Zhang T, Tian Q
Aging 2021 May 29;13(11):15078-15099
Aging 2021 May 29;13(11):15078-15099
PET-CT and RNA sequencing reveal novel targets for acupuncture-induced lowering of blood pressure in spontaneously hypertensive rats.
Li J, Peng C, Lai D, Fang Y, Luo D, Zhou Z, Li C, Lai X
Scientific reports 2021 May 26;11(1):10973
Scientific reports 2021 May 26;11(1):10973
Induced Pluripotent Stem Cell-Derived Conditioned Medium Promotes Endogenous Leukemia Inhibitory Factor to Attenuate Endotoxin-Induced Acute Lung Injury.
Su VY, Chiou SH, Chen WC, Yu WK, Wu HH, Chen H, Yang KY
International journal of molecular sciences 2021 May 24;22(11)
International journal of molecular sciences 2021 May 24;22(11)
Evaluation of the nephrotoxicity and safety of low-dose aristolochic acid, extending to the use of Xixin (Asurum), by determination of methylglyoxal and d-lactate.
Lin CE, Lin PY, Yang WC, Huang YS, Lin TY, Chen CM, Chen HS, Lee JA, Chen SM
Journal of ethnopharmacology 2021 May 23;272:113945
Journal of ethnopharmacology 2021 May 23;272:113945
The novel prognostic risk factor STC2 can regulate the occurrence and progression of osteosarcoma via the glycolytic pathway.
Yu B, Zhang F, Liu L, Liang Y, Tang X, Peng Y, Cai F, Zeng D, Yuan X, Li J, Guo Y, Lv B, Wang M, Liao Q, Lv XB
Biochemical and biophysical research communications 2021 May 21;554:25-32
Biochemical and biophysical research communications 2021 May 21;554:25-32
Doxorubicin and PD-L1 siRNA co-delivery with stem cell membrane-coated polydopamine nanoparticles for the targeted chemoimmunotherapy of PCa bone metastases.
Mu X, Zhang M, Wei A, Yin F, Wang Y, Hu K, Jiang J
Nanoscale 2021 May 21;13(19):8998-9008
Nanoscale 2021 May 21;13(19):8998-9008
Essential Role of CRIM1 on Endometrial Receptivity in Goat.
Yang D, Liu A, Zhang Y, Nan S, Yin R, Lei Q, Zhu H, Chen J, Han L, Ding M, Ding Y
International journal of molecular sciences 2021 May 18;22(10)
International journal of molecular sciences 2021 May 18;22(10)
Differentially expressed genes induced by β-caryophyllene in a rat model of cerebral ischemia-reperfusion injury.
Liu S, Liu J, Wang Y, Deng L, Chen S, Wang X, Zuo T, Hu Q, Rao J, Wang Q, Dong Z
Life sciences 2021 May 15;273:119293
Life sciences 2021 May 15;273:119293
Protective effect of recombinant Lactobacillus plantarum against H(2)O(2)-induced oxidative stress in HUVEC cells.
Wang G, Hao M, Liu Q, Jiang Y, Huang H, Yang G, Wang C
Journal of Zhejiang University. Science. B 2021 May 15;22(5):348-365
Journal of Zhejiang University. Science. B 2021 May 15;22(5):348-365
The HDAC and PI3K dual inhibitor CUDC-907 synergistically enhances the antileukemic activity of venetoclax in preclinical models of acute myeloid leukemia.
Li X, Su Y, Hege K, Madlambayan G, Edwards H, Knight T, Polin L, Kushner J, Dzinic SH, White K, Yang J, Miller R, Wang G, Zhao L, Wang Y, Lin H, Taub JW, Ge Y
Haematologica 2021 May 1;106(5):1262-1277
Haematologica 2021 May 1;106(5):1262-1277
Glucagon-like peptide-1 (GLP-1) improved diabetic lung fibrosis via AMPK and microRNA-27a (miR-27a).
Liu J, Li X, Lu S, Zheng X, Zhang X, Zhao W
Annals of translational medicine 2021 Mar;9(6):492
Annals of translational medicine 2021 Mar;9(6):492
Angiotensin II-mediated improvement of renal mitochondrial function via the AMPK/PGC-1α/NRF-2 pathway is superior to norepinephrine in a rat model of septic shock associated with acute renal injury.
An H, Hu Z, Chen Y, Cheng L, Shi J, Han L
Annals of translational medicine 2021 Mar;9(6):481
Annals of translational medicine 2021 Mar;9(6):481
Low expression of BTN3A3 indicates poor prognosis and promotes cell proliferation, migration and invasion in non-small cell lung cancer.
Cheng X, Ma T, Yi L, Su C, Wang X, Wen T, Wang B, Wang Y, Zhang H, Liu Z
Annals of translational medicine 2021 Mar;9(6):478
Annals of translational medicine 2021 Mar;9(6):478
Protein kinase D participates in cardiomyocyte hypertrophy by regulating extracellular signal-regulated and myocyte enhancer factor 2D.
Yuan H, Xiang Q, Yang L, Geng J
Revista portuguesa de cardiologia 2021 Mar;40(3):191-200
Revista portuguesa de cardiologia 2021 Mar;40(3):191-200
The novel ALK inhibitor ZX-29 induces apoptosis through inhibiting ALK and inducing ROS-mediated endoplasmic reticulum stress in Karpas299 cells.
Zhou X, Zhang X, Wu Z, Xu X, Guo M, Zhai X, Zuo D, Wu Y
Journal of biochemical and molecular toxicology 2021 Mar;35(3):e22666
Journal of biochemical and molecular toxicology 2021 Mar;35(3):e22666
Effects of photoperiod on morphology and function in testis and epididymis of Cricetulus barabensis.
Mou J, Xu J, Wang Z, Wang C, Yang X, Wang X, Xue H, Wu M, Xu L
Journal of cellular physiology 2021 Mar;236(3):2109-2125
Journal of cellular physiology 2021 Mar;236(3):2109-2125
Resveratrol induces human colorectal cancer cell apoptosis by activating the mitochondrial pathway via increasing reactive oxygen species.
Fu Y, Ye Y, Zhu G, Xu Y, Sun J, Wu H, Feng F, Wen Z, Jiang S, Li Y, Zhang Q
Molecular medicine reports 2021 Mar;23(3)
Molecular medicine reports 2021 Mar;23(3)
Curcumin suppresses colorectal tumorigenesis via the Wnt/β-catenin signaling pathway by downregulating Axin2.
Hao J, Dai X, Gao J, Li Y, Hou Z, Chang Z, Wang Y
Oncology letters 2021 Mar;21(3):186
Oncology letters 2021 Mar;21(3):186
Different effects of high-fat diets rich in different oils on lipids metabolism, oxidative stress and gut microbiota.
Liu H, Zhu H, Xia H, Yang X, Yang L, Wang S, Wen J, Sun G
Food research international (Ottawa, Ont.) 2021 Mar;141:110078
Food research international (Ottawa, Ont.) 2021 Mar;141:110078
MALAT1 sponges miR-26a and miR-26b to regulate endothelial cell angiogenesis via PFKFB3-driven glycolysis in early-onset preeclampsia.
Li Q, Liu X, Liu W, Zhang Y, Wu M, Chen Z, Zhao Y, Zou L
Molecular therapy. Nucleic acids 2021 Mar 5;23:897-907
Molecular therapy. Nucleic acids 2021 Mar 5;23:897-907
TDP-43 and PINK1 mediate CHCHD10(S59L) mutation-induced defects in Drosophila and in vitro.
Baek M, Choe YJ, Bannwarth S, Kim J, Maitra S, Dorn GW 2nd, Taylor JP, Paquis-Flucklinger V, Kim NC
Nature communications 2021 Mar 26;12(1):1924
Nature communications 2021 Mar 26;12(1):1924
The combination of G-CSF and AMD3100 mobilizes bone marrow-derived stem cells to protect against cisplatin-induced acute kidney injury in mice.
Chen Z, Ren X, Ren R, Wang Y, Shang J
Stem cell research & therapy 2021 Mar 24;12(1):209
Stem cell research & therapy 2021 Mar 24;12(1):209
GR/NF-κB signaling pathway regulates hippocampal inflammatory responses in diabetic rats with chronic unpredictable mild stress.
Li ZR, Han YS, Liu Z, Zhao HQ, Liu J, Yang H, Wang YH
European journal of pharmacology 2021 Mar 15;895:173861
European journal of pharmacology 2021 Mar 15;895:173861
Exposure to Melamine cyanuric acid in adolescent mice caused emotional disorder and behavioral disorder.
Wang S, Zhang J, Zhang S, Shi F, Feng D, Feng X
Ecotoxicology and environmental safety 2021 Mar 15;211:111938
Ecotoxicology and environmental safety 2021 Mar 15;211:111938
Identification and functional analysis of senescence-associated secretory phenotype of premature senescent hepatocytes induced by hexavalent chromium.
Ma Y, Liang Y, Liang N, Zhang Y, Xiao F
Ecotoxicology and environmental safety 2021 Mar 15;211:111908
Ecotoxicology and environmental safety 2021 Mar 15;211:111908
Overexpression of Annexin A2 promotes proliferation by forming a Glypican 1/c-Myc positive feedback loop: prognostic significance in human glioma.
Li X, Nie S, Lv Z, Ma L, Song Y, Hu Z, Hu X, Liu Z, Zhou G, Dai Z, Song T, Liu J, Wang S
Cell death & disease 2021 Mar 12;12(3):261
Cell death & disease 2021 Mar 12;12(3):261
Dietary seaweed-derived polysaccharides improve growth performance of weaned pigs through maintaining intestinal barrier function and modulating gut microbial populations.
Zou T, Yang J, Guo X, He Q, Wang Z, You J
Journal of animal science and biotechnology 2021 Mar 10;12(1):28
Journal of animal science and biotechnology 2021 Mar 10;12(1):28
Dihydroxyeicosatrienoic Acid, a Metabolite of Epoxyeicosatrienoic Acids Upregulates Endothelial Nitric Oxide Synthase Expression Through Transcription: Mechanism of Vascular Endothelial Function Protection.
Zuo D, Pi Q, Shi Y, Luo S, Xia Y
Cell biochemistry and biophysics 2021 Jun;79(2):289-299
Cell biochemistry and biophysics 2021 Jun;79(2):289-299
CLIC1 Inhibition Protects Against Cellular Senescence and Endothelial Dysfunction Via the Nrf2/HO-1 Pathway.
Lu D, Le Y, Ding J, Dou X, Mao W, Zhu J
Cell biochemistry and biophysics 2021 Jun;79(2):239-252
Cell biochemistry and biophysics 2021 Jun;79(2):239-252
Prenatal High-Sucrose Diet Induced Vascular Dysfunction in Thoracic Artery of Fetal Offspring.
Feng X, Yu T, Zhang Y, Li L, Qu M, Wang J, Dong F, Zhang L, Wang F, Zhang F, Zhou X, Xu Z, Man D
Molecular nutrition & food research 2021 Jun;65(12):e2100072
Molecular nutrition & food research 2021 Jun;65(12):e2100072
Targeting the p300/NONO axis sensitizes melanoma cells to BRAF inhibitors.
Zhang F, Tang X, Fan S, Liu X, Sun J, Ju C, Liang Y, Liu R, Zhou R, Yu B, Zhang C, Zhang Z, Kang T, Huang G, Lv XB
Oncogene 2021 Jun;40(24):4137-4150
Oncogene 2021 Jun;40(24):4137-4150
Interleukin-1 induces receptor activator of nuclear factor-κB ligand-independent osteoclast differentiation in RAW264.7 cells.
Liao R, Feng Z, Li W, Liu R, Xu X, Yao S, Tian J
Experimental and therapeutic medicine 2021 Jun;21(6):640
Experimental and therapeutic medicine 2021 Jun;21(6):640
The Role of Nrf2 on the Cognitive Dysfunction of High-fat Diet Mice Following Lead Exposure.
Zhang L, Bo J, Chen W, Li S, Wang Y, Yan L, Wu L, Zhang Y
Biological trace element research 2021 Jun;199(6):2247-2258
Biological trace element research 2021 Jun;199(6):2247-2258
Isolation, characterization and transcriptome analysis of porcine deltacoronavirus strain HNZK-02 from Henan Province, China.
Jin XH, Zhang YF, Yuan YX, Han L, Zhang GP, Hu H
Molecular immunology 2021 Jun;134:86-99
Molecular immunology 2021 Jun;134:86-99
Melatonin inhibits lipid accumulation to repress prostate cancer progression by mediating the epigenetic modification of CES1.
Zhou L, Zhang C, Yang X, Liu L, Hu J, Hou Y, Tao H, Sugimura H, Chen Z, Wang L, Chen K
Clinical and translational medicine 2021 Jun;11(6):e449
Clinical and translational medicine 2021 Jun;11(6):e449
Endoplasmic reticulum stress manipulates autophagic response that antagonizes polybrominated diphenyl ethers quinone induced cytotoxicity in microglial BV2 cells.
Zhu Q, Liu Z, Wang Y, Song E, Song Y
Journal of hazardous materials 2021 Jun 5;411:124958
Journal of hazardous materials 2021 Jun 5;411:124958
LINC00511 drives invasive behavior in hepatocellular carcinoma by regulating exosome secretion and invadopodia formation.
Peng X, Li X, Yang S, Huang M, Wei S, Ma Y, Li Y, Wu B, Jin H, Li B, Tang S, Fan Q, Liu J, Yang L, Li H
Journal of experimental & clinical cancer research : CR 2021 Jun 4;40(1):183
Journal of experimental & clinical cancer research : CR 2021 Jun 4;40(1):183
YTHDF1 promotes hepatocellular carcinoma progression via activating PI3K/AKT/mTOR signaling pathway and inducing epithelial-mesenchymal transition.
Luo X, Cao M, Gao F, He X
Experimental hematology & oncology 2021 Jun 4;10(1):35
Experimental hematology & oncology 2021 Jun 4;10(1):35
A metabolic data-driven systems pharmacology strategy for decoding and validating the mechanism of Compound Kushen Injection against HCC.
Wang KX, Chen YP, Lu AP, Du GH, Qin XM, Guan DG, Gao L
Journal of ethnopharmacology 2021 Jun 28;274:114043
Journal of ethnopharmacology 2021 Jun 28;274:114043
Antiviral effects of ergosterol peroxide in a pig model of porcine deltacoronavirus (PDCoV) infection involves modulation of apoptosis and tight junction in the small intestine.
Duan C, Wang J, Liu Y, Zhang J, Si J, Hao Z, Wang J
Veterinary research 2021 Jun 14;52(1):86
Veterinary research 2021 Jun 14;52(1):86
Effects of total flavonoids from Eucommia ulmoides Oliv. leaves on polycystic ovary syndrome with insulin resistance model rats induced by letrozole combined with a high-fat diet.
Peng MF, Tian S, Song YG, Li CX, Miao MS, Ren Z, Li M
Journal of ethnopharmacology 2021 Jun 12;273:113947
Journal of ethnopharmacology 2021 Jun 12;273:113947
CENPE contributes to pulmonary vascular remodeling in pulmonary hypertension.
Fang X, Xie M, Liu X, He Y
Biochemical and biophysical research communications 2021 Jun 11;557:40-47
Biochemical and biophysical research communications 2021 Jun 11;557:40-47
Insulin injections inhibits PTZ-induced mitochondrial dysfunction, oxidative stress and neurological deficits via the SIRT1/PGC-1α/SIRT3 pathway.
Cheng Y, Zeng X, Mai Q, Bai X, Jiang Y, Li J, Fan S, Ding H
Biochimica et biophysica acta. Molecular basis of disease 2021 Jun 1;1867(6):166124
Biochimica et biophysica acta. Molecular basis of disease 2021 Jun 1;1867(6):166124
Diosmetin ameliorate type 2 diabetic mellitus by up-regulating Corynebacterium glutamicum to regulate IRS/PI3K/AKT-mediated glucose metabolism disorder in KK-Ay mice.
Gong X, Xiong L, Bi C, Zhang B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jul;87:153582
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jul;87:153582
PI3K/AKT pathway mediates the antidepressant- and anxiolytic-like roles of hydrogen sulfide in streptozotocin-induced diabetic rats via promoting hippocampal neurogenesis.
Jiang W, Tang YY, Zhu WW, Li C, Zhang P, Li RQ, Chen YJ, Zou W, Tang XQ
Neurotoxicology 2021 Jul;85:201-208
Neurotoxicology 2021 Jul;85:201-208
Cathepsin K deficiency promotes alveolar bone regeneration by promoting jaw bone marrow mesenchymal stem cells proliferation and differentiation via glycolysis pathway.
Zhang W, Dong Z, Li D, Li B, Liu Y, Zheng X, Liu H, Zhou H, Hu K, Xue Y
Cell proliferation 2021 Jul;54(7):e13058
Cell proliferation 2021 Jul;54(7):e13058
HORMAD1 promotes docetaxel resistance in triple negative breast cancer by enhancing DNA damage tolerance.
Zong B, Sun L, Peng Y, Wang Y, Yu Y, Lei J, Zhang Y, Guo S, Li K, Liu S
Oncology reports 2021 Jul;46(1)
Oncology reports 2021 Jul;46(1)
Hypoxic acclimation improves cardiac redox homeostasis and protects heart against ischemia-reperfusion injury through upregulation of O-GlcNAcylation.
Ou W, Liang Y, Qin Y, Wu W, Xie M, Zhang Y, Zhang Y, Ji L, Yu H, Li T
Redox biology 2021 Jul;43:101994
Redox biology 2021 Jul;43:101994
The SESAME complex regulates cell senescence through the generation of acetyl-CoA.
Chen W, Yu X, Wu Y, Tang J, Yu Q, Lv X, Zha Z, Hu B, Li X, Chen J, Ma L, Workman JL, Li S
Nature metabolism 2021 Jul;3(7):983-1000
Nature metabolism 2021 Jul;3(7):983-1000
Advanced maternal age causes premature placental senescence and malformation via dysregulated α-Klotho expression in trophoblasts.
Chen Z, Xiong L, Jin H, Yu J, Li X, Fu H, Wen L, Qi H, Tong C, Saffery R, Kilby MD, Baker PN
Aging cell 2021 Jul;20(7):e13417
Aging cell 2021 Jul;20(7):e13417
SPOP negatively regulates Toll-like receptor-induced inflammation by disrupting MyD88 self-association.
Hu YH, Wang Y, Wang F, Dong YM, Jiang WL, Wang YP, Zhong X, Ma LX
Cellular & molecular immunology 2021 Jul;18(7):1708-1717
Cellular & molecular immunology 2021 Jul;18(7):1708-1717
Cimigenoside functions as a novel γ-secretase inhibitor and inhibits the proliferation or metastasis of human breast cancer cells by γ-secretase/Notch axis.
Jia H, Liu M, Wang X, Jiang Q, Wang S, Santhanam RK, Lv C, Zhao Q, Lu J
Pharmacological research 2021 Jul;169:105686
Pharmacological research 2021 Jul;169:105686
Medioresinol as a novel PGC-1α activator prevents pyroptosis of endothelial cells in ischemic stroke through PPARα-GOT1 axis.
Wang Y, Guan X, Gao CL, Ruan W, Zhao S, Kai G, Li F, Pang T
Pharmacological research 2021 Jul;169:105640
Pharmacological research 2021 Jul;169:105640
Resveratrol attenuates manganese-induced oxidative stress and neuroinflammation through SIRT1 signaling in mice.
Cong L, Lei MY, Liu ZQ, Liu ZF, Ma Z, Liu K, Li J, Deng Y, Liu W, Xu B
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Jul;153:112283
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Jul;153:112283
Shenmai injection improves doxorubicin cardiotoxicity via miR-30a/Beclin 1.
Zhang X, Lv S, Zhang W, Jia Q, Wang L, Ding Y, Yuan P, Zhu Y, Liu L, Li Y, Zhang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111582
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111582
Ethanol extract of Ardisiae Japonicae Herba inhibits hepatoma carcinoma cell proliferation in vitro through regulating lipid metabolism.
Gong X, Cui HT, Bian YH, Li YT, Wang YX, Peng YF, Wen WB, Li K, Wang HW, Zhang ZY, Zheng F
Chinese herbal medicines 2021 Jul;13(3):410-415
Chinese herbal medicines 2021 Jul;13(3):410-415
Upregulation of RNA cap methyltransferase RNMT drives ribosome biogenesis during T cell activation.
Galloway A, Kaskar A, Ditsova D, Atrih A, Yoshikawa H, Gomez-Moreira C, Suska O, Warminski M, Grzela R, Lamond AI, Darzynkiewicz E, Jemielity J, Cowling VH
Nucleic acids research 2021 Jul 9;49(12):6722-6738
Nucleic acids research 2021 Jul 9;49(12):6722-6738
Anoctamin 5 promotes osteosarcoma development by increasing degradation of Nel-like proteins 1 and 2.
Pan R, Lu Q, Ren C, Li H, Zeng F, Tian X, Chen H
Aging 2021 Jul 9;13(13):17316-17327
Aging 2021 Jul 9;13(13):17316-17327
Giardia duodenalis extracellular vesicles regulate the proinflammatory immune response in mouse macrophages in vitro via the MAPK, AKT and NF-κB pathways.
Zhao P, Cao L, Wang X, Li J, Dong J, Zhang N, Li X, Li S, Sun M, Zhang X, Liang M, Pu X, Gong P
Parasites & vectors 2021 Jul 8;14(1):358
Parasites & vectors 2021 Jul 8;14(1):358
miR-126 Controls the Apoptosis and Proliferation of Immature Porcine Sertoli Cells by Targeting the PIK3R2 Gene through the PI3K/AKT Signaling Pathway.
Tang X, Chen Y, Luo H, Bian Q, Weng B, Yang A, Chu D, Ran M, Chen B
Animals : an open access journal from MDPI 2021 Jul 30;11(8)
Animals : an open access journal from MDPI 2021 Jul 30;11(8)
Tumor protein D52 is upregulated in oral squamous carcinoma cells under hypoxia in a hypoxia-inducible-factor-independent manner and is involved in cell death resistance.
Abe Y, Mukudai Y, Kurihara M, Houri A, Chikuda J, Yaso A, Kato K, Shimane T, Shirota T
Cell & bioscience 2021 Jul 3;11(1):122
Cell & bioscience 2021 Jul 3;11(1):122
A novel chemical inhibitor suppresses breast cancer cell growth and metastasis through inhibiting HPIP oncoprotein.
Li P, Cao S, Huang Y, Zhang Y, Liu J, Cai X, Zhou L, Li J, Jiang Z, Ding L, Zheng Z, Li S, Ye Q
Cell death discovery 2021 Jul 29;7(1):198
Cell death discovery 2021 Jul 29;7(1):198
UHRF2 commissions the completion of DNA demethylation through allosteric activation by 5hmC and K33-linked ubiquitination of XRCC1.
Liu X, Xu B, Yang J, He L, Zhang Z, Cheng X, Yu H, Liu X, Jin T, Peng Y, Huang Y, Xia L, Wang Y, Wu J, Wu X, Liu S, Shan L, Yang X, Sun L, Liang J, Zhang Y, Shang Y
Molecular cell 2021 Jul 15;81(14):2960-2974.e7
Molecular cell 2021 Jul 15;81(14):2960-2974.e7
A clinically acceptable strategy for sensitizing anti-PD-1 treatment by hypoxia relief.
Jiang M, Qin B, Luo L, Li X, Shi Y, Zhang J, Luo Z, Zhu C, Guan G, Du Y, You J
Journal of controlled release : official journal of the Controlled Release Society 2021 Jul 10;335:408-419
Journal of controlled release : official journal of the Controlled Release Society 2021 Jul 10;335:408-419
Neuroinflammation induces anxiety- and depressive-like behavior by modulating neuronal plasticity in the basolateral amygdala.
Zheng ZH, Tu JL, Li XH, Hua Q, Liu WZ, Liu Y, Pan BX, Hu P, Zhang WH
Brain, behavior, and immunity 2021 Jan;91:505-518
Brain, behavior, and immunity 2021 Jan;91:505-518
Limonin ameliorates dextran sulfate sodium-induced chronic colitis in mice by inhibiting PERK-ATF4-CHOP pathway of ER stress and NF-κB signaling.
Song C, Chen J, Li X, Yang R, Cao X, Zhou L, Zhou Y, Ying H, Zhang Q, Sun Y
International immunopharmacology 2021 Jan;90:107161
International immunopharmacology 2021 Jan;90:107161
Sunitinib malate inhibits intestinal tumor development in male Apc(Min/+) mice by down-regulating inflammation-related factors with suppressing β-cateinin/c-Myc pathway and re-balancing Bcl-6 and Caspase-3.
Chen L, Xu P, Xiao Q, Chen L, Li S, Jian JM, Zhong YB
International immunopharmacology 2021 Jan;90:107128
International immunopharmacology 2021 Jan;90:107128
Astragaloside IV inhibits cell proliferation and metastasis of breast cancer via promoting the long noncoding RNA TRHDE-AS1.
Hu S, Zheng W, Jin L
Journal of natural medicines 2021 Jan;75(1):156-166
Journal of natural medicines 2021 Jan;75(1):156-166
A novel peptide relieves endothelial cell dysfunction in preeclampsia by regulating the PI3K/mTOR/HIF1α pathway.
Xue L, Xie K, Wu L, Yu X, Long W, Li C, Jia R, Ding H
International journal of molecular medicine 2021 Jan;47(1):276-288
International journal of molecular medicine 2021 Jan;47(1):276-288
MSH6 Aggravates the Hypoxic Microenvironment via Regulating HIF1A to Promote the Metastasis of Glioblastoma Multiforme.
Shi Y, Jiang J, Cui Y, Chen Y, Dong T, An H, Liu P
DNA and cell biology 2021 Jan;40(1):93-100
DNA and cell biology 2021 Jan;40(1):93-100
Mefunidone ameliorates diabetic kidney disease in STZ and db/db mice.
Jiang Y, Xie F, Lv X, Wang S, Liao X, Yu Y, Dai Q, Zhang Y, Meng J, Hu G, Peng Z, Tao L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21198
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21198
Evaluation of piggyBac-mediated anti-CD19 CAR-T cells after ex vivo expansion with aAPCs or magnetic beads.
Yang LR, Li L, Meng MY, Wang WJ, Yang SL, Zhao YY, Wang RQ, Gao H, Tang WW, Yang Y, Yang LL, Liao LW, Hou ZL
Journal of cellular and molecular medicine 2021 Jan;25(2):686-700
Journal of cellular and molecular medicine 2021 Jan;25(2):686-700
Carbohydrate response element-binding protein regulates lipid metabolism via mTOR complex1 in diabetic nephropathy.
Chen N, Mu L, Yang Z, Du C, Wu M, Song S, Yuan C, Shi Y
Journal of cellular physiology 2021 Jan;236(1):625-640
Journal of cellular physiology 2021 Jan;236(1):625-640
Bone marrow stem cells therapy alleviates vascular injury in a chronic obstructive pulmonary disease‑obstructive sleep apnea overlap syndrome rat model.
Bi H, He J, He X, Du J, Chen M, Huang Z, Yang C, Yang L, Li H, Zhou K, Wang Q, He L, Jin Z
Molecular medicine reports 2021 Jan;23(1)
Molecular medicine reports 2021 Jan;23(1)
Induction of autophagy by Beclin-1 in granulosa cells contributes to follicular progesterone elevation in ovarian endometriosis.
Ding Y, Zhu Q, He Y, Lu Y, Wang Y, Qi J, Wu H, Xu R, Li J, Li X, Sun Y
Translational research : the journal of laboratory and clinical medicine 2021 Jan;227:15-29
Translational research : the journal of laboratory and clinical medicine 2021 Jan;227:15-29
Protective effect of naringenin against cadmium-induced testicular toxicity in male SD rats.
Wang J, Zhu H, Lin S, Wang K, Wang H, Liu Z
Journal of inorganic biochemistry 2021 Jan;214:111310
Journal of inorganic biochemistry 2021 Jan;214:111310
The cGAS-STING signaling pathway contributes to the inflammatory response and autophagy in Aspergillus fumigatus keratitis.
Han F, Guo H, Wang L, Zhang Y, Sun L, Dai C, Wu X
Experimental eye research 2021 Jan;202:108366
Experimental eye research 2021 Jan;202:108366
EPZ015666, a selective protein arginine methyltransferase 5 (PRMT5) inhibitor with an antitumour effect in retinoblastoma.
Liu X, He J, Mao L, Zhang Y, Cui W, Duan S, Jiang A, Gao Y, Sang Y, Huang G
Experimental eye research 2021 Jan;202:108286
Experimental eye research 2021 Jan;202:108286
IKKβ activation promotes amphisome formation and extracellular vesicle secretion in tumor cells.
Peng X, Yang L, Ma Y, Li X, Yang S, Li Y, Wu B, Tang S, Zhang F, Zhang B, Liu J, Li H
Biochimica et biophysica acta. Molecular cell research 2021 Jan;1868(1):118857
Biochimica et biophysica acta. Molecular cell research 2021 Jan;1868(1):118857
Trichostatin A increases BDNF protein expression by improving XBP-1s/ATF6/GRP78 axis in Schwann cells of diabetic peripheral neuropathy.
An J, Zhang X, Jia K, Zhang C, Zhu L, Cheng M, Li F, Zhao S, Hao J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jan;133:111062
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jan;133:111062
Hypoxia-induced FOXO4/LDHA axis modulates gastric cancer cell glycolysis and progression.
Wang XH, Jiang ZH, Yang HM, Zhang Y, Xu LH
Clinical and translational medicine 2021 Jan;11(1):e279
Clinical and translational medicine 2021 Jan;11(1):e279
A Cas9-transcription factor fusion protein enhances homology-directed repair efficiency.
Li G, Wang H, Zhang X, Wu Z, Yang H
The Journal of biological chemistry 2021 Jan-Jun;296:100525
The Journal of biological chemistry 2021 Jan-Jun;296:100525
Huaier Inhibits Proliferation, Migration, and Invasion of Cutaneous Squamous Cell Carcinoma Cells by Inhibiting the Methylation Levels of CDKN2A and TP53.
Wang L, Xu L, Wang Y
Integrative cancer therapies 2021 Jan-Dec;20:15347354211031646
Integrative cancer therapies 2021 Jan-Dec;20:15347354211031646
ING5 Inhibits Migration and Invasion of Esophageal Cancer Cells by Downregulating the IL-6/CXCL12 Signaling Pathway.
Wang Y, Tan J, Li J, Chen H, Wang W
Technology in cancer research & treatment 2021 Jan-Dec;20:15330338211039940
Technology in cancer research & treatment 2021 Jan-Dec;20:15330338211039940
Obacunone Attenuates Liver Fibrosis with Enhancing Anti-Oxidant Effects of GPx-4 and Inhibition of EMT.
Bai Y, Wang W, Wang L, Ma L, Zhai D, Wang F, Shi R, Liu C, Xu Q, Chen G, Lu Z
Molecules (Basel, Switzerland) 2021 Jan 9;26(2)
Molecules (Basel, Switzerland) 2021 Jan 9;26(2)
TRIM21-regulated Annexin A2 plasma membrane trafficking facilitates osteosarcoma cell differentiation through the TFEB-mediated autophagy.
Zhang HT, Zeng Q, Wu B, Lu J, Tong KL, Lin J, Liu QY, Xu L, Yang J, Liu X, Liu W, Zhang YF, Lian Q, Liu L, Gao X
Cell death & disease 2021 Jan 6;12(1):21
Cell death & disease 2021 Jan 6;12(1):21
Nrf2 overexpression increases risk of high tumor mutation burden in acute myeloid leukemia by inhibiting MSH2.
Liu P, Ma D, Wang P, Pan C, Fang Q, Wang J
Cell death & disease 2021 Jan 5;12(1):20
Cell death & disease 2021 Jan 5;12(1):20
Sterol and oxysterol synthases near the ciliary base activate the Hedgehog pathway.
Findakly S, Daggubati V, Garcia G, LaStella SA, Choudhury A, Tran C, Li A, Tong P, Garcia JQ, Puri N, Reiter JF, Xu L, Raleigh DR
The Journal of cell biology 2021 Jan 4;220(1)
The Journal of cell biology 2021 Jan 4;220(1)
Autophagy impairment as a key feature for acetaminophen-induced ototoxicity.
Zhao T, Zheng T, Yu H, Hu BH, Hu B, Ma P, Yang Y, Yang N, Hu J, Cao T, Chen G, Yan B, Peshoff M, Hatzoglou M, Geng R, Li B, Zheng QY
Cell death & disease 2021 Jan 4;12(1):3
Cell death & disease 2021 Jan 4;12(1):3
Formaldehyde induces ferroptosis in hippocampal neuronal cells by upregulation of the Warburg effect.
Li XN, Yang SQ, Li M, Li XS, Tian Q, Xiao F, Tang YY, Kang X, Wang CY, Zou W, Zhang P, Tang XQ
Toxicology 2021 Jan 30;448:152650
Toxicology 2021 Jan 30;448:152650
Fucoxanthin extracted from Laminaria Japonica inhibits metastasis and enhances the sensitivity of lung cancer to Gefitinib.
Ming JX, Wang ZC, Huang Y, Ohishi H, Wu RJ, Shao Y, Wang H, Qin MY, Wu ZL, Li YY, Chang Zhou S, Chen H, Liu H, Xu R
Journal of ethnopharmacology 2021 Jan 30;265:113302
Journal of ethnopharmacology 2021 Jan 30;265:113302
A deafness-associated tRNA mutation caused pleiotropic effects on the m1G37 modification, processing, stability and aminoacylation of tRNAIle and mitochondrial translation.
Meng F, Zhou M, Xiao Y, Mao X, Zheng J, Lin J, Lin T, Ye Z, Cang X, Fu Y, Wang M, Guan MX
Nucleic acids research 2021 Jan 25;49(2):1075-1093
Nucleic acids research 2021 Jan 25;49(2):1075-1093
Circ-NOLC1 promotes epithelial ovarian cancer tumorigenesis and progression by binding ESRP1 and modulating CDK1 and RhoA expression.
Chen S, Wu W, Li QH, Xie BM, Shen F, Du YP, Zong ZH, Wang LL, Wei XQ, Zhao Y
Cell death discovery 2021 Jan 22;7(1):22
Cell death discovery 2021 Jan 22;7(1):22
Cdk5-Mediated Phosphorylation of Sirt1 Contributes to Podocyte Mitochondrial Dysfunction in Diabetic Nephropathy.
Wang S, Yang Y, He X, Yang L, Wang J, Xia S, Liu D, Liu S, Yang L, Liu W, Duan H
Antioxidants & redox signaling 2021 Jan 20;34(3):171-190
Antioxidants & redox signaling 2021 Jan 20;34(3):171-190
A key role of gut microbiota-vagus nerve/spleen axis in sleep deprivation-mediated aggravation of systemic inflammation after LPS administration.
Zhang Y, Xie B, Chen X, Zhang J, Yuan S
Life sciences 2021 Jan 15;265:118736
Life sciences 2021 Jan 15;265:118736
Let-7a regulates EV secretion and mitochondrial oxidative phosphorylation by targeting SNAP23 in colorectal cancer.
Liu YD, Zhuang XP, Cai DL, Cao C, Gu QS, Liu XN, Zheng BB, Guan BJ, Yu L, Li JK, Ding HB, Yan DW
Journal of experimental & clinical cancer research : CR 2021 Jan 14;40(1):31
Journal of experimental & clinical cancer research : CR 2021 Jan 14;40(1):31
Bushen Huoxue recipe attenuates early pregnancy loss via activating endometrial COX2-PGE2 angiogenic signaling in mice.
Song Y, Zhou F, Tan X, Liu X, Ding J, Zhang C, Li F, Zhu W, Ma W, Hu R, Zhang M
BMC complementary medicine and therapies 2021 Jan 14;21(1):36
BMC complementary medicine and therapies 2021 Jan 14;21(1):36
CDCA4 suppresses epithelial-mesenchymal transtion (EMT) and metastasis in Non-small cell lung cancer through modulating autophagy.
Xu C, Cao H, Sui Y, Zhang H, Shi C, Wu J, Ma R, Feng J
Cancer cell international 2021 Jan 12;21(1):48
Cancer cell international 2021 Jan 12;21(1):48
L-type amino acid transporter 1 is associated with chemoresistance in breast cancer via the promotion of amino acid metabolism.
Sato M, Harada-Shoji N, Toyohara T, Soga T, Itoh M, Miyashita M, Tada H, Amari M, Anzai N, Furumoto S, Abe T, Suzuki T, Ishida T, Sasano H
Scientific reports 2021 Jan 12;11(1):589
Scientific reports 2021 Jan 12;11(1):589
Changes in the prefrontal cortex after the hippocampus was injected with Aβ(25-35) via the P35/P25-CDK5-Tau hyperphosphorylation signaling pathway.
Wang Y, Sheng H, Zhao J, Guo L, Liu J, Xu J, Liu Q, Huang J, Jiang R, Gan S, Qiu G, Lu W, Xu S, Zhu S
Neuroscience letters 2021 Jan 10;741:135453
Neuroscience letters 2021 Jan 10;741:135453
Eradicating intracellular MRSA via targeted delivery of lysostaphin and vancomycin with mannose-modified exosomes.
Yang X, Xie B, Peng H, Shi G, Sreenivas B, Guo J, Wang C, He Y
Journal of controlled release : official journal of the Controlled Release Society 2021 Jan 10;329:454-467
Journal of controlled release : official journal of the Controlled Release Society 2021 Jan 10;329:454-467
Metformin alleviates high glucose-induced ER stress and inflammation by inhibiting the interaction between caveolin1 and AMPKα in rat astrocytes.
Wang G, Cui W, Chen S, Shao Z, Li Y, Wang W, Mao L, Li J, Mei X
Biochemical and biophysical research communications 2021 Jan 1;534:908-913
Biochemical and biophysical research communications 2021 Jan 1;534:908-913
ActivinA activates Notch1-Shh signaling to regulate proliferation in C2C12 skeletal muscle cells.
Ma L, Li C, Lian S, Xu B, Yuan J, Lu J, Yang H, Guo J, Ji H
Molecular and cellular endocrinology 2021 Jan 1;519:111055
Molecular and cellular endocrinology 2021 Jan 1;519:111055
Disrupted eNOS activity and expression account for vasodilator dysfunction in different stage of sepsis.
Hu S, Pi Q, Xu X, Yan J, Guo Y, Tan W, He A, Cheng Z, Luo S, Xia Y
Life sciences 2021 Jan 1;264:118606
Life sciences 2021 Jan 1;264:118606
Anti-renal interstitial fibrosis effect of norcantharidin is exerted through inhibition of PP2Ac-mediated C-terminal phosphorylation of Smad3.
Luo HW, Yin DD, Xiao Z, Wen L, Liao YJ, Tang CY, Zeng D, Xiao HT, Li Y
Chemical biology & drug design 2021 Feb;97(2):293-304
Chemical biology & drug design 2021 Feb;97(2):293-304
Syndecan 4 contributes to osteoclast differentiation induced by RANKL through enhancing autophagy.
Li J, Sun Z, Lin Y, Yan Y, Yan H, Jing B, Han Z
International immunopharmacology 2021 Feb;91:107275
International immunopharmacology 2021 Feb;91:107275
Type 1 interferon aggravates lipopolysaccharide-induced sepsis through upregulating Caspase-11 and Gasdermin D.
Wang Y, Zhang X, Guo Y, Li X, Guo G, Niu Z, Zhang J
Journal of physiology and biochemistry 2021 Feb;77(1):85-92
Journal of physiology and biochemistry 2021 Feb;77(1):85-92
Effect of claudin 1 on cell proliferation, migration and apoptosis in human cervical squamous cell carcinoma.
Shen Z, Song W, Qian L, Zhu J, Li Y, Li M, Zhang T, Zhao W, Zhou Y, Yang X
Oncology reports 2021 Feb;45(2):606-618
Oncology reports 2021 Feb;45(2):606-618
Sodium alginate/collagen hydrogel loaded with human umbilical cord mesenchymal stem cells promotes wound healing and skin remodeling.
Zhang Z, Li Z, Li Y, Wang Y, Yao M, Zhang K, Chen Z, Yue H, Shi J, Guan F, Ma S
Cell and tissue research 2021 Feb;383(2):809-821
Cell and tissue research 2021 Feb;383(2):809-821
Downregulating lncRNA PRNCR1 ameliorates LPS-induced pulmonary vascular endothelial cell injury by modulating miR-330-5p/TLR4 axis.
Yu Y, Sun H, Zhu L, Ji L, Liu H
Journal of biochemical and molecular toxicology 2021 Feb;35(2):e22644
Journal of biochemical and molecular toxicology 2021 Feb;35(2):e22644
NPM1 mutant maintains ULK1 protein stability via TRAF6-dependent ubiquitination to promote autophagic cell survival in leukemia.
Tang Y, Tao Y, Wang L, Yang L, Jing Y, Jiang X, Lei L, Yang Z, Wang X, Peng M, Xiao Q, Ren J, Zhang L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21192
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21192
Cell membrane-encapsulated magnetic nanoparticles for enhancing natural killer cell-mediated cancer immunotherapy.
Wu D, Shou X, Zhang Y, Li Z, Wu G, Wu D, Wu J, Shi S, Wang S
Nanomedicine : nanotechnology, biology, and medicine 2021 Feb;32:102333
Nanomedicine : nanotechnology, biology, and medicine 2021 Feb;32:102333
BML-111, the lipoxin A(4) agonist, modulates VEGF or CoCl(2)-induced migration, angiogenesis and permeability in tumor-derived endothelial cells.
Lin L, Wang Q, Xu F, Luo X, Xu J, Yan L, Li Q, Hao H
Immunology letters 2021 Feb;230:27-35
Immunology letters 2021 Feb;230:27-35
MicroRNA‑338‑3p regulates age‑associated osteoporosis via targeting PCSK5.
Tong J, Zhang M, Li X, Ren G
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
Luteolin attenuates angiotensin II‑induced renal damage in apolipoprotein E‑deficient mice.
Liu YS, Yang Q, Li S, Luo L, Liu HY, Li XY, Gao ZN
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
Exercise reduces hyperlipidemia-induced kidney damage in apolipoprotein E-deficient mice.
Qian C, Yang Q, Guo L, Zhu H, You X, Liu H, Sun Y
Experimental and therapeutic medicine 2021 Feb;21(2):153
Experimental and therapeutic medicine 2021 Feb;21(2):153
F-Box protein 4 inhibits progression of papillary thyroid cancer.
Xu M, Wang Y, Chen M, Hu H, Xia T, Deng D
Steroids 2021 Feb;166:108773
Steroids 2021 Feb;166:108773
Novel clerodane-type diterpenoid Cintelactone A suppresses lipopolysaccharide -induced inflammation by promoting ubiquitination, proteasomal degradation of TRAF6.
Di Q, Zhao X, Zhang R, Ma X, Liang X, Li X, Gao J, Tang H, Chen W, Xiao W
Pharmacological research 2021 Feb;164:105386
Pharmacological research 2021 Feb;164:105386
Osteogenic differentiation and calcification of human aortic smooth muscle cells is induced by the RCN2/STAT3/miR-155-5p feedback loop.
Zhao J, Liu Z, Chang Z
Vascular pharmacology 2021 Feb;136:106821
Vascular pharmacology 2021 Feb;136:106821
Study on the protective effect and mechanism of Dicliptera chinensis (L.) Juss (Acanthaceae) polysaccharide on immune liver injury induced by LPS.
Xu Q, Xu J, Zhang K, Zhong M, Cao H, Wei R, Jin L, Gao Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Feb;134:111159
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Feb;134:111159
Impact of knockdown LincRNA-Cox2 on apoptosis of macrophage infected with Bacillus Calmette-Guérin.
Xu Y, Yu J, Ma C, Gong Z, Wu X, Deng G
Molecular immunology 2021 Feb;130:85-95
Molecular immunology 2021 Feb;130:85-95
Bach2 overexpression represses Th9 cell differentiation by suppressing IRF4 expression in systemic lupus erythematosus.
Sheng Y, Zhang J, Li K, Wang H, Wang W, Wen L, Gao J, Tang X, Tang H, Huang H, Cai M, Yuan T, Liu L, Zheng X, Zhu Z, Cui Y
FEBS open bio 2021 Feb;11(2):395-403
FEBS open bio 2021 Feb;11(2):395-403
Hypothermic oxygenated perfusion inhibits HECTD3-mediated TRAF3 polyubiquitination to alleviate DCD liver ischemia-reperfusion injury.
Zhou W, Zhong Z, Lin D, Liu Z, Zhang Q, Xia H, Peng S, Liu A, Lu Z, Wang Y, Ye S, Ye Q
Cell death & disease 2021 Feb 24;12(2):211
Cell death & disease 2021 Feb 24;12(2):211
An ESCRT-dependent step in fatty acid transfer from lipid droplets to mitochondria through VPS13D-TSG101 interactions.
Wang J, Fang N, Xiong J, Du Y, Cao Y, Ji WK
Nature communications 2021 Feb 23;12(1):1252
Nature communications 2021 Feb 23;12(1):1252
SEPHS1 promotes SMAD2/3/4 expression and hepatocellular carcinoma cells invasion.
Yang S, Zhang H, Yang H, Zhang J, Wang J, Luo T, Jiang Y, Hua H
Experimental hematology & oncology 2021 Feb 23;10(1):17
Experimental hematology & oncology 2021 Feb 23;10(1):17
Anti-NMDAR encephalitis induced in mice by active immunization with a peptide from the amino-terminal domain of the GluN1 subunit.
Ding Y, Zhou Z, Chen J, Peng Y, Wang H, Qiu W, Xie W, Zhang J, Wang H
Journal of neuroinflammation 2021 Feb 21;18(1):53
Journal of neuroinflammation 2021 Feb 21;18(1):53
Macrophage migration inhibitory factor activates the inflammatory response in joint capsule fibroblasts following post-traumatic joint contracture.
Zhang Y, Lu S, Fan S, Xu L, Jiang X, Wang K, Cai B
Aging 2021 Feb 17;13(4):5804-5823
Aging 2021 Feb 17;13(4):5804-5823
Rational design and synthesis of 6-aryl-6H-benzo[c]chromenes as non-steroidal progesterone receptor antagonists for use against cancers.
Qin J, Qu S, Zhu K, Cheng Y, Pan G, Jing W, Liu X, Sun X, Liu L
Bioorganic & medicinal chemistry 2021 Feb 15;32:116003
Bioorganic & medicinal chemistry 2021 Feb 15;32:116003
A genome-wide CRISPR screen identifies host factors that regulate SARS-CoV-2 entry.
Zhu Y, Feng F, Hu G, Wang Y, Yu Y, Zhu Y, Xu W, Cai X, Sun Z, Han W, Ye R, Qu D, Ding Q, Huang X, Chen H, Xu W, Xie Y, Cai Q, Yuan Z, Zhang R
Nature communications 2021 Feb 11;12(1):961
Nature communications 2021 Feb 11;12(1):961
Stabilizing mast cells improves acute lung injury after orthotopic liver transplantation via promotion of apoptosis in polymorphonuclear neutrophils.
Chen C, Zhang Z, Tan F, Meng F, Lai L, Chi X, Zhu Q
American journal of physiology. Lung cellular and molecular physiology 2021 Feb 1;320(2):L266-L275
American journal of physiology. Lung cellular and molecular physiology 2021 Feb 1;320(2):L266-L275
Prenylated xanthones from mangosteen (Garcinia mangostana) activate the AhR and Nrf2 pathways and protect intestinal barrier integrity in HT-29 cells.
Tocmo R, Le B, Heun A, van Pijkeren JP, Parkin K, Johnson JJ
Free radical biology & medicine 2021 Feb 1;163:102-115
Free radical biology & medicine 2021 Feb 1;163:102-115
ABIN-1 is a key regulator in RIPK1-dependent apoptosis (RDA) and necroptosis, and ABIN-1 deficiency potentiates necroptosis-based cancer therapy in colorectal cancer.
Cai J, Hu D, Sakya J, Sun T, Wang D, Wang L, Mao X, Su Z
Cell death & disease 2021 Feb 1;12(2):140
Cell death & disease 2021 Feb 1;12(2):140
Ataxia-telangiectasia mutated interacts with Parkin and induces mitophagy independent of kinase activity. Evidence from mantle cell lymphoma.
Sarkar A, Stellrecht CM, Vangapandu HV, Ayres M, Kaipparettu BA, Park JH, Balakrishnan K, Burks JK, Pandita TK, Hittelman WN, Neelapu SS, Gandhi V
Haematologica 2021 Feb 1;106(2):495-512
Haematologica 2021 Feb 1;106(2):495-512
Compound Kushen Injection intervenes metabolic reprogramming and epithelial-mesenchymal transition of HCC via regulating β-catenin/c-Myc signaling.
Wang KX, Du GH, Qin XM, Gao L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Dec;93:153781
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Dec;93:153781
Dendrobium nobile Lindl alkaloid attenuates 6-OHDA-induced dopamine neurotoxicity.
Li DD, Wang GQ, Wu Q, Shi JS, Zhang F
Biotechnology and applied biochemistry 2021 Dec;68(6):1501-1507
Biotechnology and applied biochemistry 2021 Dec;68(6):1501-1507
Simiao Qingwen Baidu decoction inhibits Epstein-Barr virus-induced B lymphoproliferative disease and lytic viral replication.
Yang X, Liu L, Zhang H, Sun X, Yan Y, Ran R
Pharmaceutical biology 2021 Dec;59(1):741-747
Pharmaceutical biology 2021 Dec;59(1):741-747
Chrysanthemi Flos extract alleviated acetaminophen-induced rat liver injury via inhibiting oxidative stress and apoptosis based on network pharmacology analysis.
Zhou Y, Wang C, Kou J, Wang M, Rong X, Pu X, Xie X, Han G, Pang X
Pharmaceutical biology 2021 Dec;59(1):1378-1387
Pharmaceutical biology 2021 Dec;59(1):1378-1387
Bone marrow macrophage-derived exosomal miR-143-5p contributes to insulin resistance in hepatocytes by repressing MKP5.
Li L, Zuo H, Huang X, Shen T, Tang W, Zhang X, An T, Dou L, Li J
Cell proliferation 2021 Dec;54(12):e13140
Cell proliferation 2021 Dec;54(12):e13140
Hsa_circ_0042823 accelerates cancer progression via miR-877-5p/FOXM1 axis in laryngeal squamous cell carcinoma.
Wu T, Sun Y, Sun Z, Li S, Wang W, Yu B, Wang G
Annals of medicine 2021 Dec;53(1):960-970
Annals of medicine 2021 Dec;53(1):960-970
Azathioprine pretreatment ameliorates myocardial ischaemia reperfusion injury in diabetic rats by reducing oxidative stress, apoptosis, and inflammation.
Lu C, Liu L, Chen S, Niu J, Li S, Xie W, Cheng X
Clinical and experimental pharmacology & physiology 2021 Dec;48(12):1621-1632
Clinical and experimental pharmacology & physiology 2021 Dec;48(12):1621-1632
Triptolide regulates oxidative stress and inflammation leading to hepatotoxicity via inducing CYP2E1.
Jiang HY, Bao YN, Lin FM, Jin Y
Human & experimental toxicology 2021 Dec;40(12_suppl):S775-S787
Human & experimental toxicology 2021 Dec;40(12_suppl):S775-S787
Non-canonical activation of the ER stress sensor ATF6 by Legionella pneumophila effectors.
Ibe NU, Subramanian A, Mukherjee S
Life science alliance 2021 Dec;4(12)
Life science alliance 2021 Dec;4(12)
Ramelteon Mitigates Free Fatty Acid (FFA)-Induced Attachment of Monocytes to Brain Vascular Endothelial Cells.
Wang G, Tian F, Li Y, Liu Y, Liu C
Neurotoxicity research 2021 Dec;39(6):1937-1945
Neurotoxicity research 2021 Dec;39(6):1937-1945
Acetabular development and fate of inverted limbus in rabbits: Experimental observation from an animal model.
Liu J, Zhou W, Chen Y, Li L
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2021 Dec;39(12):2595-2603
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2021 Dec;39(12):2595-2603
Bergenin alleviates H(2) O(2) -induced oxidative stress and apoptosis in nucleus pulposus cells: Involvement of the PPAR-γ/NF-κB pathway.
Zhang G, Wang H, Zhang Q, Zhao Z, Zhu W, Zuo X
Environmental toxicology 2021 Dec;36(12):2541-2550
Environmental toxicology 2021 Dec;36(12):2541-2550
ChREBP deficiency alleviates apoptosis by inhibiting TXNIP/oxidative stress in diabetic nephropathy.
Chen N, Song S, Yang Z, Wu M, Mu L, Zhou T, Shi Y
Journal of diabetes and its complications 2021 Dec;35(12):108050
Journal of diabetes and its complications 2021 Dec;35(12):108050
Low EGR1 expression predicts poor prognosis in clear cell renal cell carcinoma.
Zhang ZY, Zhang SL, Chen HL, Mao YQ, Kong CY, Li ZM, Wang LS, Ma M, Han B
Pathology, research and practice 2021 Dec;228:153666
Pathology, research and practice 2021 Dec;228:153666
TRIP4 transcriptionally activates DDIT4 and subsequent mTOR signaling to promote glioma progression.
Li W, Hu S, Tian C, Wan X, Yu W, Guo P, Zhao F, Hua C, Lu X, Xue G, Han S, Guo W, Wang D, Deng W
Free radical biology & medicine 2021 Dec;177:31-47
Free radical biology & medicine 2021 Dec;177:31-47
Pretreatment of Indobufen and Aspirin and their Combinations with Clopidogrel or Ticagrelor Alleviates Inflammasome Mediated Pyroptosis Via Inhibiting NF-κB/NLRP3 Pathway in Ischemic Stroke.
Li F, Xu D, Hou K, Gou X, Lv N, Fang W, Li Y
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2021 Dec;16(4):835-853
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2021 Dec;16(4):835-853
Empagliflozin protects diabetic pancreatic tissue from damage by inhibiting the activation of the NLRP3/caspase-1/GSDMD pathway in pancreatic β cells: in vitro and in vivo studies.
Liu P, Zhang Z, Wang J, Zhang X, Yu X, Li Y
Bioengineered 2021 Dec;12(2):9356-9366
Bioengineered 2021 Dec;12(2):9356-9366
The effects of Omarigliptin on promoting osteoblastic differentiation.
Liao F, Hu X, Chen R
Bioengineered 2021 Dec;12(2):11837-11846
Bioengineered 2021 Dec;12(2):11837-11846
High expression of transmembrane P24 trafficking protein 9 predicts poor prognosis in breast carcinoma.
Ju G, Xu C, Zeng K, Zhou T, Zang L
Bioengineered 2021 Dec;12(1):8965-8979
Bioengineered 2021 Dec;12(1):8965-8979
MiR-130a-3p suppresses colorectal cancer growth by targeting Wnt Family Member 1 (WNT1).
Song GL, Xiao M, Wan XY, Deng J, Ling JD, Tian YG, Li M, Yin J, Zheng RY, Tang Y, Liu GY
Bioengineered 2021 Dec;12(1):8407-8418
Bioengineered 2021 Dec;12(1):8407-8418
Silencing circular RNA circ_0054537 and upregulating microRNA-640 suppress malignant progression of renal cell carcinoma via regulating neuronal pentraxin-2 (NPTX2).
Pei L, Lv X, Jia G, Tan X, Li M, Zhang A
Bioengineered 2021 Dec;12(1):8279-8295
Bioengineered 2021 Dec;12(1):8279-8295
Soy isoflavones alleviate polycystic ovary syndrome in rats by regulating NF- κB signaling pathway.
Ma X, Li X, Ma L, Chen Y, He S
Bioengineered 2021 Dec;12(1):7215-7223
Bioengineered 2021 Dec;12(1):7215-7223
Hypoxia-inducible factor-1alpha protects the liver against ischemia-reperfusion injury by regulating the A2B adenosine receptor.
Zhang X, Du P, Luo K, Li Y, Liu Z, Wang W, Zeng C, Ye Q, Xiao Q
Bioengineered 2021 Dec;12(1):3737-3752
Bioengineered 2021 Dec;12(1):3737-3752
M2 Macrophage-derived exosomal miR-501 contributes to pubococcygeal muscle regeneration.
Zhou M, Li B, Liu C, Hu M, Tang J, Min J, Cheng J, Hong L
International immunopharmacology 2021 Dec;101(Pt B):108223
International immunopharmacology 2021 Dec;101(Pt B):108223
Biomimetic amphiphilic FAAP NPs nanoparticles: Synthesis, characterization and antivirus activity.
Li XH, Zhang Z, Ma X, Guo ZH, Ban X, Tian Z, Zhao L, Liu Q, He Q
International immunopharmacology 2021 Dec;101(Pt A):108047
International immunopharmacology 2021 Dec;101(Pt A):108047
Screening and Identification of Differential Ovarian Proteins before and after Induced Ovulation via Seminal Plasma in Bactrian Camels.
Wang Q, Zhang Q, Li Y, Zhao X, Zhang Y
Animals : an open access journal from MDPI 2021 Dec 9;11(12)
Animals : an open access journal from MDPI 2021 Dec 9;11(12)
Fyn kinase regulates dopaminergic neuronal apoptosis in animal and cell models of high glucose (HG) treatment.
Tan C, Liu X, Zhang X, Peng W, Wang H, Zhou W, Jiang J, Mo L, Chen Y, Chen L
BMC molecular and cell biology 2021 Dec 4;22(1):58
BMC molecular and cell biology 2021 Dec 4;22(1):58
Long non-coding RNA CRNDE exacerbates NPC advancement mediated by the miR-545-5p/CCND2 axis.
Ge S, Jiang C, Li M, Cheng Z, Feng X
Cancer cell international 2021 Dec 4;21(1):650
Cancer cell international 2021 Dec 4;21(1):650
T-2 Toxin Induces Ferroptosis by Increasing Lipid Reactive Oxygen Species (ROS) and Downregulating Solute Carrier Family 7 Member 11 (SLC7A11).
Wang G, Qin S, Zheng Y, Xia C, Zhang P, Zhang L, Yao J, Yi Y, Deng L
Journal of agricultural and food chemistry 2021 Dec 29;69(51):15716-15727
Journal of agricultural and food chemistry 2021 Dec 29;69(51):15716-15727
Esophageal Cancer Stem-like Cells Resist Ferroptosis-Induced Cell Death by Active Hsp27-GPX4 Pathway.
Liu CC, Li HH, Lin JH, Chiang MC, Hsu TW, Li AF, Yen DH, Hsu HS, Hung SC
Biomolecules 2021 Dec 29;12(1)
Biomolecules 2021 Dec 29;12(1)
Urolithin a alleviates oxidative stress-induced senescence in nucleus pulposus-derived mesenchymal stem cells through SIRT1/PGC-1α pathway.
Shi PZ, Wang JW, Wang PC, Han B, Lu XH, Ren YX, Feng XM, Cheng XF, Zhang L
World journal of stem cells 2021 Dec 26;13(12):1928-1946
World journal of stem cells 2021 Dec 26;13(12):1928-1946
Aureonitol Analogues and Orsellinic Acid Esters Isolated from Chaetomium elatum and Their Antineuroinflammatory Activity.
Ju F, Kuang QX, Li QZ, Huang LJ, Guo WX, Gong LQ, Dai YF, Wang L, Gu YC, Wang D, Deng Y, Guo DL
Journal of natural products 2021 Dec 24;84(12):3044-3054
Journal of natural products 2021 Dec 24;84(12):3044-3054
Dietary supplementation of inulin alleviates metabolism disorders in gestational diabetes mellitus mice via RENT/AKT/IRS/GLUT4 pathway.
Miao M, Dai Y, Rui C, Fan Y, Wang X, Fan C, Mu J, Hou W, Dong Z, Li P, Sun G, Zeng X
Diabetology & metabolic syndrome 2021 Dec 24;13(1):150
Diabetology & metabolic syndrome 2021 Dec 24;13(1):150
Black Tea Alleviates Particulate Matter-Induced Lung Injury via the Gut-Lung Axis in Mice.
Zhao Y, Chen X, Shen J, Xu A, Wang Y, Meng Q, Xu P
Journal of agricultural and food chemistry 2021 Dec 22;69(50):15362-15373
Journal of agricultural and food chemistry 2021 Dec 22;69(50):15362-15373
GADD34-mediated dephosphorylation of eIF2α facilitates pseudorabies virus replication by maintaining de novo protein synthesis.
Zhu T, Jiang X, Xin H, Zheng X, Xue X, Chen JL, Qi B
Veterinary research 2021 Dec 20;52(1):148
Veterinary research 2021 Dec 20;52(1):148
Expression, purification and characterisation of a human anti-CDK4 single-chain variable fragment antibody.
Zhao J, Xu J, Yang T, Yu X, Cheng C, Zhang T, Ren Z, Li N, Yang F, Li G
BMC biotechnology 2021 Dec 20;21(1):71
BMC biotechnology 2021 Dec 20;21(1):71
Tryptophanyl tRNA Synthetase from Human Macrophages Infected by Porphyromonas gingivalis Induces a Proinflammatory Response Associated with Atherosclerosis.
Sasaki M, Shimoyama Y, Kodama Y, Ishikawa T
Pathogens (Basel, Switzerland) 2021 Dec 20;10(12)
Pathogens (Basel, Switzerland) 2021 Dec 20;10(12)
Oxygen nanocarrier broke the hypoxia trap of solid tumors and rescued transfection efficiency for gene therapy.
Qin B, Jiang M, Li X, Shi Y, Zhang J, Luo Z, Luo L, Lu Y, Liu X, Wang S, Du Y, Qiu Y, Lou Y, You J
Journal of nanobiotechnology 2021 Dec 18;19(1):427
Journal of nanobiotechnology 2021 Dec 18;19(1):427
Aroylhydrazone Diorganotin Complexes Causes DNA Damage and Apoptotic Cell Death: From Chemical Synthesis to Biochemical Effects.
Jiang W, Tan Y, Peng Y
International journal of molecular sciences 2021 Dec 16;22(24)
International journal of molecular sciences 2021 Dec 16;22(24)
Calcium alleviates fluoride-induced kidney damage via FAS/FASL, TNFR/TNF, DR5/TRAIL pathways in rats.
Li H, Fan J, Zhao Y, Yang J, Xu H, Manthari RK, Cheng X, Wang J, Wang J
Ecotoxicology and environmental safety 2021 Dec 15;226:112851
Ecotoxicology and environmental safety 2021 Dec 15;226:112851
Circular RNA circEsyt2 regulates vascular smooth muscle cell remodeling via splicing regulation.
Gong X, Tian M, Cao N, Yang P, Xu Z, Zheng S, Liao Q, Chen C, Zeng C, Jose PA, Wang DZ, Jian Z, Xiao Y, Jiang DS, Wei X, Zhang B, Wang Y, Chen K, Wu G, Zeng C
The Journal of clinical investigation 2021 Dec 15;131(24)
The Journal of clinical investigation 2021 Dec 15;131(24)
BLM helicase inhibition synergizes with PARP inhibition to improve the radiosensitivity of olaparib resistant non-small cell lung cancer cells by inhibiting homologous recombination repair.
Kong Y, Xu C, Sun X, Sun H, Zhao X, He N, Ji K, Wang Q, Du L, Wang J, Zhang M, Liu Y, Wang Y, Liu Q
Cancer biology & medicine 2021 Dec 1;19(8):1150-71
Cancer biology & medicine 2021 Dec 1;19(8):1150-71
Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Rac Exchanger 2 Protein Facilitates Glioma Progression via Akt and Stat3 Signaling.
Shang J, Li Y, Yin G, Li Z, Jiang L, Bai Q
Journal of molecular neuroscience : MN 2021 Aug;71(8):1674-1682
Journal of molecular neuroscience : MN 2021 Aug;71(8):1674-1682
Guanosine and uridine alleviate airway inflammation via inhibition of the MAPK and NF-κB signals in OVA-induced asthmatic mice.
Luo Y, Chen H, Huang R, Wu Q, Li Y, He Y
Pulmonary pharmacology & therapeutics 2021 Aug;69:102049
Pulmonary pharmacology & therapeutics 2021 Aug;69:102049
Diosgenin Protects Against Kidney Injury and Mitochondrial Apoptosis Induced by 3-MCPD Through the Regulation of ER Stress, Ca(2+) Homeostasis, and Bcl2 Expression.
Zhong Y, Jin C, Han J, Zhu J, Liu Q, Sun D, Xia X, Zhang Y, Peng X
Molecular nutrition & food research 2021 Aug;65(15):e2001202
Molecular nutrition & food research 2021 Aug;65(15):e2001202
Dental pulp stem cell-derived exosomes alleviate cerebral ischaemia-reperfusion injury through suppressing inflammatory response.
Li S, Luo L, He Y, Li R, Xiang Y, Xing Z, Li Y, Albashari AA, Liao X, Zhang K, Gao L, Ye Q
Cell proliferation 2021 Aug;54(8):e13093
Cell proliferation 2021 Aug;54(8):e13093
Hippocampal CA1 theta burst-induced LTP from weaning to adulthood: Cellular and molecular mechanisms in young male rats revisited.
Rodrigues NC, Silva-Cruz A, Caulino-Rocha A, Bento-Oliveira A, Alexandre Ribeiro J, Cunha-Reis D
The European journal of neuroscience 2021 Aug;54(4):5272-5292
The European journal of neuroscience 2021 Aug;54(4):5272-5292
Glutaredoxin 1 protects neurons from oxygen-glucose deprivation/reoxygenation (OGD/R)-induced apoptosis and oxidative stress via the modulation of GSK-3β/Nrf2 signaling.
Qiu Z, Li X, Duan C, Li R, Han L
Journal of bioenergetics and biomembranes 2021 Aug;53(4):369-379
Journal of bioenergetics and biomembranes 2021 Aug;53(4):369-379
MicroRNA-122 contributes to lipopolysaccharide-induced acute kidney injury via down-regulating the vitamin D receptor in the kidney.
He J, Du J, Yi B, Wang J, Zhang H, Li YC, Sun J
European journal of clinical investigation 2021 Aug;51(8):e13547
European journal of clinical investigation 2021 Aug;51(8):e13547
H(2)S Attenuates Sleep Deprivation-Induced Cognitive Impairment by Reducing Excessive Autophagy via Hippocampal Sirt-1 in WISTAR RATS.
Gao S, Tang YY, Jiang L, Lan F, Li X, Zhang P, Zou W, Chen YJ, Tang XQ
Neurochemical research 2021 Aug;46(8):1941-1952
Neurochemical research 2021 Aug;46(8):1941-1952
CQMUH-011 Inhibits LPS-Induced Microglia Activation and Ameliorates Brain Ischemic Injury in Mice.
Liu H, Hu X, Jiang R, Cai J, Lin Q, Fan Z, Zhao P, Wang S, Zou C, Du W, Dong Z, Liu Y
Inflammation 2021 Aug;44(4):1345-1358
Inflammation 2021 Aug;44(4):1345-1358
Quercetin hinders microglial activation to alleviate neurotoxicity via the interplay between NLRP3 inflammasome and mitophagy.
Han X, Xu T, Fang Q, Zhang H, Yue L, Hu G, Sun L
Redox biology 2021 Aug;44:102010
Redox biology 2021 Aug;44:102010
The p53/p21/p16 and PI3K/Akt signaling pathways are involved in the ameliorative effects of maltol on D-galactose-induced liver and kidney aging and injury.
Sha JY, Li JH, Zhou YD, Yang JY, Liu W, Jiang S, Wang YP, Zhang R, Di P, Li W
Phytotherapy research : PTR 2021 Aug;35(8):4411-4424
Phytotherapy research : PTR 2021 Aug;35(8):4411-4424
LncRNA-AC006129.1 reactivates a SOCS3-mediated anti-inflammatory response through DNA methylation-mediated CIC downregulation in schizophrenia.
Ni C, Jiang W, Wang Z, Wang Z, Zhang J, Zheng X, Liu Z, Ou H, Jiang T, Liang W, Wu F, Li Q, Hou Y, Yang Q, Guo B, Liu S, Li S, Li S, Yang E, Zhu XH, Huang X, Wen Z, Zhao C
Molecular psychiatry 2021 Aug;26(8):4511-4528
Molecular psychiatry 2021 Aug;26(8):4511-4528
The molecular mechanism underlying mitophagy-mediated hippocampal neuron apoptosis in diabetes-related depression.
Liu J, Liu L, Han YS, Yi J, Guo C, Zhao HQ, Ling J, Wang YH
Journal of cellular and molecular medicine 2021 Aug;25(15):7342-7353
Journal of cellular and molecular medicine 2021 Aug;25(15):7342-7353
Resveratrol affects the expression of uric acid transporter by improving inflammation.
Zhang X, Nie Q, Zhang Z, Zhao J, Zhang F, Wang C, Wang X, Song G
Molecular medicine reports 2021 Aug;24(2)
Molecular medicine reports 2021 Aug;24(2)
Aggravation of hepatic ischemia‑reperfusion injury with increased inflammatory cell infiltration is associated with the TGF‑β/Smad3 signaling pathway.
Li H, Shen X, Tong Y, Ji T, Feng Y, Tang Y, Mai R, Ye J, Que T, Luo X
Molecular medicine reports 2021 Aug;24(2)
Molecular medicine reports 2021 Aug;24(2)
miR-320a in serum exosomes promotes myocardial fibroblast proliferation via regulating the PIK3CA/Akt/mTOR signaling pathway in HEH2 cells.
Wang QG, Cheng BC, He YZ, Li LJ, Ling Y, Luo G, Wang L, Liang S, Zhang Y
Experimental and therapeutic medicine 2021 Aug;22(2):873
Experimental and therapeutic medicine 2021 Aug;22(2):873
Augmenter of liver regeneration ameliorates ischemia-reperfusion injury in steatotic liver via inhibition of the TLR4/NF-κB pathway.
Weng J, Wang X, Xu B, Li W
Experimental and therapeutic medicine 2021 Aug;22(2):863
Experimental and therapeutic medicine 2021 Aug;22(2):863
DNMT1-mediated PPARα methylation aggravates damage of retinal tissues in diabetic retinopathy mice.
Zhu Y, Wang X, Zhou X, Ding L, Liu D, Xu H
Biological research 2021 Aug 6;54(1):25
Biological research 2021 Aug 6;54(1):25
Ginsenoside Rg5 Improves Insulin Resistance and Mitochondrial Biogenesis of Liver via Regulation of the Sirt1/PGC-1α Signaling Pathway in db/db Mice.
Zhu Y, Yang H, Deng J, Fan D
Journal of agricultural and food chemistry 2021 Aug 4;69(30):8428-8439
Journal of agricultural and food chemistry 2021 Aug 4;69(30):8428-8439
The screening of drug-induced nephrotoxicity using gold nanocluster-based ratiometric fluorescent probes.
Liu Q, Li J, Liu X, Yuan L, Zhao L, Chang YT, Liu X, Peng J
Nanoscale 2021 Aug 28;13(32):13835-13844
Nanoscale 2021 Aug 28;13(32):13835-13844
YWHAZ interacts with DAAM1 to promote cell migration in breast cancer.
Mei J, Liu Y, Yu X, Hao L, Ma T, Zhan Q, Zhang Y, Zhu Y
Cell death discovery 2021 Aug 27;7(1):221
Cell death discovery 2021 Aug 27;7(1):221
Effects of RNA methylation N6-methyladenosine regulators on malignant progression and prognosis of melanoma.
Liu J, Zhou Z, Ma L, Li C, Lin Y, Yu T, Wei JF, Zhu L, Yao G
Cancer cell international 2021 Aug 26;21(1):453
Cancer cell international 2021 Aug 26;21(1):453
The Performance of HepG2 and HepaRG Systems through the Glass of Acetaminophen-Induced Toxicity.
Lőrincz T, Deák V, Makk-Merczel K, Varga D, Hajdinák P, Szarka A
Life (Basel, Switzerland) 2021 Aug 21;11(8)
Life (Basel, Switzerland) 2021 Aug 21;11(8)
USP15 participates in DBP-induced testicular oxidative stress injury through regulating the Keap1/Nrf2 signaling pathway.
Zhang L, Gao X, Qin Z, Shi X, Xu K, Wang S, Tang M, Wang W, Gao S, Zuo L, Zhang L, Zhang W
The Science of the total environment 2021 Aug 20;783:146898
The Science of the total environment 2021 Aug 20;783:146898
Reactive microglia enhance the transmission of exosomal α-synuclein via toll-like receptor 2.
Xia Y, Zhang G, Kou L, Yin S, Han C, Hu J, Wan F, Sun Y, Wu J, Li Y, Huang J, Xiong N, Zhang Z, Wang T
Brain : a journal of neurology 2021 Aug 17;144(7):2024-2037
Brain : a journal of neurology 2021 Aug 17;144(7):2024-2037
Expression pattern and regulatory effect of lysine-specific demethylase 2A gene in clear cell renal cell carcinoma.
Wang J, Li T, Li X, Zhang Y, Wang X
BMC urology 2021 Aug 14;21(1):108
BMC urology 2021 Aug 14;21(1):108
Serum exosomal pregnancy zone protein as a promising biomarker in inflammatory bowel disease.
Shao J, Jin Y, Shao C, Fan H, Wang X, Yang G
Cellular & molecular biology letters 2021 Aug 10;26(1):36
Cellular & molecular biology letters 2021 Aug 10;26(1):36
KIM-1-mediated anti-inflammatory activity is preserved by MUC1 induction in the proximal tubule during ischemia-reperfusion injury.
Al-Bataineh MM, Kinlough CL, Mi Z, Jackson EK, Mutchler SM, Emlet DR, Kellum JA, Hughey RP
American journal of physiology. Renal physiology 2021 Aug 1;321(2):F135-F148
American journal of physiology. Renal physiology 2021 Aug 1;321(2):F135-F148
CIHH protects the heart against left ventricular remodelling and myocardial fibrosis by balancing the renin-angiotensin system in SHR.
Yu B, Chen H, Guo XQ, Hua H, Guan Y, Cui F, Tian YM, Zhang HX, Zhang XJ, Zhang Y, Ma HJ
Life sciences 2021 Aug 1;278:119540
Life sciences 2021 Aug 1;278:119540
Virtual screening identified natural Keap1-Nrf2 PPI inhibitor alleviates inflammatory osteoporosis through Nrf2-mir214-Traf3 axis.
Hong J, Shi Z, Li C, Ji X, Li S, Chen Y, Jiang G, Shi M, Wang W, Zhang Y, Hu B, Yan S
Free radical biology & medicine 2021 Aug 1;171:365-378
Free radical biology & medicine 2021 Aug 1;171:365-378
The canonical smooth muscle cell marker TAGLN is present in endothelial cells and is involved in angiogenesis.
Tsuji-Tamura K, Morino-Koga S, Suzuki S, Ogawa M
Journal of cell science 2021 Aug 1;134(15)
Journal of cell science 2021 Aug 1;134(15)
Contribution of the NLRP3/IL-1β axis to impaired vasodilation in sepsis through facilitation of eNOS proteolysis and the protective role of melatonin.
Hu S, Pi Q, Luo M, Cheng Z, Liang X, Luo S, Xia Y
International immunopharmacology 2021 Apr;93:107388
International immunopharmacology 2021 Apr;93:107388
Autocrined leptin promotes proliferation of non-small cell lung cancer (NSCLC) via PI3K/AKT and p53 pathways.
Wang J, Zhou F, Li F, Wang B, Hu Y, Li X
Annals of translational medicine 2021 Apr;9(7):568
Annals of translational medicine 2021 Apr;9(7):568
Morusin inhibits the growth of human colorectal cancer HCT116‑derived sphere‑forming cells via the inactivation of Akt pathway.
Zhou Y, Li X, Ye M
International journal of molecular medicine 2021 Apr;47(4):1
International journal of molecular medicine 2021 Apr;47(4):1
MMP11 promotes the proliferation and progression of breast cancer through stabilizing Smad2 protein.
Zhuang Y, Li X, Zhan P, Pi G, Wen G
Oncology reports 2021 Apr;45(4)
Oncology reports 2021 Apr;45(4)
BOP1 Silencing Suppresses Gastric Cancer Proliferation through p53 Modulation.
Yang YP, Qin RH, Zhao JJ, Qin XY
Current medical science 2021 Apr;41(2):287-296
Current medical science 2021 Apr;41(2):287-296
Effect of luteinizing hormone concentration on transcriptome and subcellular organelle phenotype of ovarian granulosa cells.
Wan YT, Liu S, Zhao SK, Luo YY, Lv YS, Qu DN, Liu MH, Li Y
Journal of assisted reproduction and genetics 2021 Apr;38(4):809-824
Journal of assisted reproduction and genetics 2021 Apr;38(4):809-824
CRSP8 promotes thyroid cancer progression by antagonizing IKKα-induced cell differentiation.
Liao Y, Hua Y, Li Y, Zhang C, Yu W, Guo P, Zou K, Li W, Sun Y, Wang R, Zuo Y, Sui S, Tian C, Hao J, Chen M, Hu S, Chen M, Long Q, Wang X, Zou L, Xie F, Guo W, Deng W
Cell death and differentiation 2021 Apr;28(4):1347-1363
Cell death and differentiation 2021 Apr;28(4):1347-1363
Enhanced response to PD-L1 silencing by modulation of TME via balancing glucose metabolism and robust co-delivery of siRNA/Resveratrol with dual-responsive polyplexes.
Jia L, Gao Y, Zhou T, Zhao XL, Hu HY, Chen DW, Qiao MX
Biomaterials 2021 Apr;271:120711
Biomaterials 2021 Apr;271:120711
Zinc provides neuroprotection by regulating NLRP3 inflammasome through autophagy and ubiquitination in a spinal contusion injury model.
Lin JQ, Tian H, Zhao XG, Lin S, Li DY, Liu YY, Xu C, Mei XF
CNS neuroscience & therapeutics 2021 Apr;27(4):413-425
CNS neuroscience & therapeutics 2021 Apr;27(4):413-425
Honokiol induces paraptosis-like cell death of acute promyelocytic leukemia via mTOR & MAPK signaling pathways activation.
Liu X, Gu Y, Bian Y, Cai D, Li Y, Zhao Y, Zhang Z, Xue M, Zhang L
Apoptosis : an international journal on programmed cell death 2021 Apr;26(3-4):195-208
Apoptosis : an international journal on programmed cell death 2021 Apr;26(3-4):195-208
Oxymatrine reduces expression of programmed death-ligand 1 by promoting DNA demethylation in colorectal cancer cells.
Hua S, Gu M, Wang Y, Ban D, Ji H
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2021 Apr;23(4):750-756
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2021 Apr;23(4):750-756
Abnormal Glu/mGluR(2/3)/PI3K pathway in the hippocampal neurovascular unit leads to diabetes-related depression.
Liu J, Han YS, Liu L, Tang L, Yang H, Meng P, Zhao HQ, Wang YH
Neural regeneration research 2021 Apr;16(4):727-733
Neural regeneration research 2021 Apr;16(4):727-733
Involvement of NADPH oxidase in patulin-induced oxidative damage and cytotoxicity in HEK293 cells.
Han J, Jin C, Zhong Y, Zhu J, Liu Q, Sun D, Feng J, Xia X, Peng X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Apr;150:112055
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Apr;150:112055
SPT6 recruits SND1 to co-activate human telomerase reverse transcriptase to promote colon cancer progression.
Diao C, Guo P, Yang W, Sun Y, Liao Y, Yan Y, Zhao A, Cai X, Hao J, Hu S, Yu W, Chen M, Wang R, Li W, Zuo Y, Pan J, Hua C, Lu X, Fan W, Zheng Z, Deng W, Luo G, Guo W
Molecular oncology 2021 Apr;15(4):1180-1202
Molecular oncology 2021 Apr;15(4):1180-1202
Change on apoptosis, autophagy and mitochondria of the Harderian gland in Cricetulus barabensis during age.
Kong XT, Wang Z, Mou JJ, Li CS, Xue HL, Wu M, Chen L, Xu JH, Xu LX
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2021 Apr-May;253:110547
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2021 Apr-May;253:110547
Downregulation of circular RNA circDOCK7 identified from diabetic rats after sleeve gastrectomy contributes to hepatocyte apoptosis through regulating miR-139-3p and MCM3.
Li L, Dong S, Li S, Xu Q, Wang S, Xiong Y, Cheng Y, Zhong M, Zhang G, Hu S
Biochemical and biophysical research communications 2021 Apr 9;548:134-142
Biochemical and biophysical research communications 2021 Apr 9;548:134-142
Smooth muscle-specific HuR knockout induces defective autophagy and atherosclerosis.
Liu S, Jiang X, Cui X, Wang J, Liu S, Li H, Yang J, Zhang C, Zhang W
Cell death & disease 2021 Apr 9;12(4):385
Cell death & disease 2021 Apr 9;12(4):385
GCG inhibits SARS-CoV-2 replication by disrupting the liquid phase condensation of its nucleocapsid protein.
Zhao M, Yu Y, Sun LM, Xing JQ, Li T, Zhu Y, Wang M, Yu Y, Xue W, Xia T, Cai H, Han QY, Yin X, Li WH, Li AL, Cui J, Yuan Z, Zhang R, Zhou T, Zhang XM, Li T
Nature communications 2021 Apr 9;12(1):2114
Nature communications 2021 Apr 9;12(1):2114
KLF5-mediated Eppk1 expression promotes cell proliferation in cervical cancer via the p38 signaling pathway.
Ma D, Pan Z, Chang Q, Zhang JJ, Liu X, Hua N, Li GH
BMC cancer 2021 Apr 8;21(1):377
BMC cancer 2021 Apr 8;21(1):377
Dexmedetomidine protects SH-SY5Y cells against MPP(+) -induced declining of mitochondrial membrane potential and cell cycle deficits.
Chen Y, Chen C, Song D, Liu T, Cheng O
The European journal of neuroscience 2021 Apr 27;
The European journal of neuroscience 2021 Apr 27;
Xanthine oxidase inhibitory activity and antihyperuricemic effect of Moringa oleifera Lam. leaf hydrolysate rich in phenolics and peptides.
Tian Y, Lin L, Zhao M, Peng A, Zhao K
Journal of ethnopharmacology 2021 Apr 24;270:113808
Journal of ethnopharmacology 2021 Apr 24;270:113808
cAMP-PKA signaling is involved in regulation of spinal HCN channels function in diabetic neuropathic pain.
Ma Y, Chen J, Yu D, Wei B, Jin H, Zeng J, Liu X
Neuroscience letters 2021 Apr 17;750:135763
Neuroscience letters 2021 Apr 17;750:135763
The SRSF1/circATP5B/miR-185-5p/HOXB5 feedback loop regulates the proliferation of glioma stem cells via the IL6-mediated JAK2/STAT3 signaling pathway.
Zhao J, Jiang Y, Zhang H, Zhou J, Chen L, Li H, Xu J, Zhang G, Jing Z
Journal of experimental & clinical cancer research : CR 2021 Apr 15;40(1):134
Journal of experimental & clinical cancer research : CR 2021 Apr 15;40(1):134
Spleen Tyrosine Kinase Mediates Microglial Activation in Mice With Diabetic Retinopathy.
Liu X, Xu B, Gao S
Translational vision science & technology 2021 Apr 1;10(4):20
Translational vision science & technology 2021 Apr 1;10(4):20
REG γ knockdown suppresses proliferation by inducing apoptosis and cell cycle arrest in osteosarcoma.
Yin Z, Jin H, Huang S, Qu G, Meng Q
PeerJ 2020;8:e8954
PeerJ 2020;8:e8954
Glutamate-Cysteine Ligase Catalytic Subunit Attenuated Hepatitis C Virus-Related Liver Fibrosis and Suppressed Endoplasmic Reticulum Stress.
Fu N, Li D, Li W, Zhao W, Zhang S, Liu L, Zhao S, Du J, Kong L, Wang R, Zhang Y, Nan Y
Frontiers in molecular biosciences 2020;7:199
Frontiers in molecular biosciences 2020;7:199
Promotion of cadmium uptake and cadmium-induced toxicity by the copper transporter CTR1 in HepG2 and ZFL cells.
Kwok ML, Li ZP, Law TYS, Chan KM
Toxicology reports 2020;7:1564-1570
Toxicology reports 2020;7:1564-1570
The Novel Synthetic Triterpene Methyl 3β-O-[4-(2-Aminoethylamino)-4-oxo-butyryl]olean-12-ene-28-oate Inhibits Breast Tumor Cell Growth in Vitro and in Vivo.
Feng B, Zhao C, Li J, Yu J, Zhang Y, Zhang X, Tian T, Zhao L
Chemical & pharmaceutical bulletin 2020;68(10):962-970
Chemical & pharmaceutical bulletin 2020;68(10):962-970
Baicalin Inhibits Coxsackievirus B3 Replication by Reducing Cellular Lipid Synthesis.
Wang MJ, Yang CH, Jin Y, Wan CB, Qian WH, Xing F, Li X, Liu YY
The American journal of Chinese medicine 2020;48(1):143-160
The American journal of Chinese medicine 2020;48(1):143-160
Anti-inflammation and anti-apoptosis effects of growth arrest-specific protein 6 in acute liver injury induced by LPS/D-GalN in mice.
Wang Q, Zhao Y, Zang B
Acta cirurgica brasileira 2020;35(2):e202000204
Acta cirurgica brasileira 2020;35(2):e202000204
Systematic investigation of biomarker-like role of ARHGDIB in breast cancer.
Wang X, Bi X, Huang X, Wang B, Guo Q, Wu Z
Cancer biomarkers : section A of Disease markers 2020;28(1):101-110
Cancer biomarkers : section A of Disease markers 2020;28(1):101-110
Xiao-Qing-Long-Tang Maintains Cardiac Function during Heart Failure with Reduced Ejection Fraction in Salt-Sensitive Rats by Regulating the Imbalance of Cardiac Sympathetic Innervation.
Li Z, Wang Y, Jiang Y, Ma D, Jiang P, Zhou G, Yang J, Dong F, Zhao H, Zhang Y, Li X
Evidence-based complementary and alternative medicine : eCAM 2020;2020:9467271
Evidence-based complementary and alternative medicine : eCAM 2020;2020:9467271
Phloretin Modulates Human Th17/Treg Cell Differentiation In Vitro via AMPK Signaling.
Jiao A, Yang Z, Fu X, Hua X
BioMed research international 2020;2020:6267924
BioMed research international 2020;2020:6267924
Role of Nrf2 in Lipopolysaccharide-Induced Acute Kidney Injury: Protection by Human Umbilical Cord Blood Mononuclear Cells.
Feng LX, Zhao F, Liu Q, Peng JC, Duan XJ, Yan P, Wu X, Wang HS, Deng YH, Duan SB
Oxidative medicine and cellular longevity 2020;2020:6123459
Oxidative medicine and cellular longevity 2020;2020:6123459
Heme Oxygenase-1 Suppresses Wnt Signaling Pathway in Nonalcoholic Steatohepatitis-Related Liver Fibrosis.
Du J, Ren W, Zhang Q, Fu N, Han F, Cui P, Li W, Kong L, Zhao S, Wang R, Zhang Y, Yang L, Kong L, Nan Y
BioMed research international 2020;2020:4910601
BioMed research international 2020;2020:4910601
Thymoquinone Protects against Hyperlipidemia-Induced Cardiac Damage in Low-Density Lipoprotein Receptor-Deficient (LDL-R(-/-)) Mice via Its Anti-inflammatory and Antipyroptotic Effects.
Pei ZW, Guo Y, Zhu HL, Dong M, Zhang Q, Wang F
BioMed research international 2020;2020:4878704
BioMed research international 2020;2020:4878704
Electroacupuncture Pretreatment Alleviates LPS-Induced Acute Respiratory Distress Syndrome via Regulating the PPAR Gamma/NF-Kappa B Signaling Pathway.
Feng D, Zhou H, Jin X, Wei J, Zhang Q, Gu Y, Zhang P, Yang H, Song J, Shi X, Lv X
Evidence-based complementary and alternative medicine : eCAM 2020;2020:4594631
Evidence-based complementary and alternative medicine : eCAM 2020;2020:4594631
Silencing ARAF Suppresses the Malignant Phenotypes of Gallbladder Cancer Cells.
Lin W, Tong C, Zhang W, Cen W, Wang Y, Li J, Zhu Z, Yu J, Lu B
BioMed research international 2020;2020:3235786
BioMed research international 2020;2020:3235786
Ellagic Acid Protects Dopamine Neurons via Inhibition of NLRP3 Inflammasome Activation in Microglia.
He XM, Zhou YZ, Sheng S, Li JJ, Wang GQ, Zhang F
Oxidative medicine and cellular longevity 2020;2020:2963540
Oxidative medicine and cellular longevity 2020;2020:2963540
miR-876 Inhibits EMT and Liver Fibrosis via POSTN to Suppress Metastasis in Hepatocellular Carcinoma.
Chen K, Li Z, Zhang M, Wang B, Peng T, Shen Y, Zhang J, Ye J, Liu Y, Tang D, Peng M, Ma D, Xiao Z, Zhang Y, Jin W, Li X
BioMed research international 2020;2020:1964219
BioMed research international 2020;2020:1964219
Anti-Inflammatory and Antioxidant Effect of Eucommia ulmoides Polysaccharide in Hepatic Ischemia-Reperfusion Injury by Regulating ROS and the TLR-4-NF-κB Pathway.
Gao W, Feng Z, Zhang S, Wu B, Geng X, Fan G, Duan Y, Li K, Liu K, Peng C
BioMed research international 2020;2020:1860637
BioMed research international 2020;2020:1860637
Effects of Hydrogen-rich Water on the PI3K/AKT Signaling Pathway in Rats with Myocardial Ischemia-reperfusion Injury.
Li L, Li X, Zhang Z, Liu L, Liu T, Li S, Liu S, Zhou Y, Liu F
Current molecular medicine 2020;20(5):396-406
Current molecular medicine 2020;20(5):396-406
A glycolysis-based 4-mRNA signature correlates with the prognosis and cell cycle process in patients with bladder cancer.
Zhang C, Gou X, He W, Yang H, Yin H
Cancer cell international 2020;20:177
Cancer cell international 2020;20:177
Structure-based discovery of neoandrographolide as a novel inhibitor of Rab5 to suppress cancer growth.
Zhang J, Sun Y, Zhong LY, Yu NN, Ouyang L, Fang RD, Wang Y, He QY
Computational and structural biotechnology journal 2020;18:3936-3946
Computational and structural biotechnology journal 2020;18:3936-3946
Nicotinamide Riboside Enhances Mitochondrial Proteostasis and Adult Neurogenesis through Activation of Mitochondrial Unfolded Protein Response Signaling in the Brain of ALS SOD1(G93A) Mice.
Zhou Q, Zhu L, Qiu W, Liu Y, Yang F, Chen W, Xu R
International journal of biological sciences 2020;16(2):284-297
International journal of biological sciences 2020;16(2):284-297
Methylglyoxal and D-lactate in cisplatin-induced acute kidney injury: Investigation of the potential mechanism via fluorogenic derivatization liquid chromatography-tandem mass spectrometry (FD-LC-MS/MS) proteomic analysis.
Chen SM, Chen TH, Chang HT, Lin TY, Lin CY, Tsai PY, Imai K, Chen CM, Lee JA
PloS one 2020;15(7):e0235849
PloS one 2020;15(7):e0235849
Interferon regulatory factor 7 mediates obesity-associated MCP-1 transcription.
Kuroda M, Nishiguchi M, Ugawa N, Ishikawa E, Kawabata Y, Okamoto S, Sasaki W, Miyatake Y, Sebe M, Masumoto S, Tsutsumi R, Harada N, Sakaue H
PloS one 2020;15(5):e0233390
PloS one 2020;15(5):e0233390
MicroRNA-9 mediated the protective effect of ferulic acid on hypoxic-ischemic brain damage in neonatal rats.
Yao K, Yang Q, Li Y, Lan T, Yu H, Yu Y
PloS one 2020;15(5):e0228825
PloS one 2020;15(5):e0228825
The effect of autophagy and mitochondrial fission on Harderian gland is greater than apoptosis in male hamsters during different photoperiods.
Xu JH, Wang Z, Mou JJ, Zhao XY, Geng XC, Wu M, Xue HL, Chen L, Xu LX
PloS one 2020;15(11):e0241561
PloS one 2020;15(11):e0241561
Utilizing methylglyoxal and D-lactate in urine to evaluate saikosaponin C treatment in mice with accelerated nephrotoxic serum nephritis.
Lin CY, Lee JA, Lin PY, Hua SC, Tsai PY, Chen BL, Lin CE, Lee TH, Chen SM
PloS one 2020;15(10):e0241053
PloS one 2020;15(10):e0241053
Effect of prednisolone on glyoxalase 1 in an inbred mouse model of aristolochic acid nephropathy using a proteomics method with fluorogenic derivatization-liquid chromatography-tandem mass spectrometry.
Chen SM, Lin CE, Chen HH, Cheng YF, Cheng HW, Imai K
PloS one 2020;15(1):e0227838
PloS one 2020;15(1):e0227838
Protective effects of essential oil from Fructus Alpiniae zerumbet on retinal Müller gliosis via the PPAR-γ-p-CREB signaling pathway.
Yang H, Gan S, Jiang Z, Song X, Chen T, Xu Y, Fu L, Zhang Y, Tao L, Shen X
Chinese medicine 2020;15:4
Chinese medicine 2020;15:4
MicroRNA 885-5p Inhibits Hepatocellular Carcinoma Metastasis by Repressing AEG1.
Li C, Wang X, Song Q
OncoTargets and therapy 2020;13:981-988
OncoTargets and therapy 2020;13:981-988
Bufalin Induces Glioma Cell Death by Apoptosis or Necroptosis.
LingHu HR, Luo H, Gang L
OncoTargets and therapy 2020;13:4767-4778
OncoTargets and therapy 2020;13:4767-4778
The Acetone Indigo Red Dehydrating Agent IF203 Induces HepG2 Cell Death Through Cell Cycle Arrest, Autophagy and Apoptosis.
Shang Y, Wang Q, Li J, Zhao Q, Huang X, Dong H, Liu H, Zhang Y, Zhang J, Gui R, Nie X
OncoTargets and therapy 2020;13:473-486
OncoTargets and therapy 2020;13:473-486
MicroRNA-375 Targets ATG14 to Inhibit Autophagy and Sensitize Hepatocellular Carcinoma Cells to Sorafenib.
Yang S, Wang M, Yang L, Li Y, Ma Y, Peng X, Li X, Li B, Jin H, Li H
OncoTargets and therapy 2020;13:3557-3570
OncoTargets and therapy 2020;13:3557-3570
Dihydroartemisinin Prevents Progression and Metastasis of Head and Neck Squamous Cell Carcinoma by Inhibiting Polarization of Macrophages in Tumor Microenvironment.
Chen R, Lu X, Li Z, Sun Y, He Z, Li X
OncoTargets and therapy 2020;13:3375-3387
OncoTargets and therapy 2020;13:3375-3387
Proteomics Analysis of Brain Tissue in a Rat Model of Ischemic Stroke in the Acute Phase.
Zheng F, Zhou YT, Zeng YF, Liu T, Yang ZY, Tang T, Luo JK, Wang Y
Frontiers in molecular neuroscience 2020;13:27
Frontiers in molecular neuroscience 2020;13:27
The Regulatory Mechanism and Biological Significance of Mitochondrial Calcium Uniporter in the Migration, Invasion, Angiogenesis and Growth of Gastric Cancer.
Wang X, Song X, Cheng G, Zhang J, Dong L, Bai J, Luo D, Xiong Y, Li S, Liu F, Sun Y, Wang X, Li Y, Huang Y
OncoTargets and therapy 2020;13:11781-11794
OncoTargets and therapy 2020;13:11781-11794
Melatonin ameliorates hyperglycaemia-induced renal inflammation by inhibiting the activation of TLR4 and TGF-β1/Smad3 signalling pathway.
Wei J, Wang Y, Qi X, Fan Z, Wu Y
American journal of translational research 2020;12(5):1584-1599
American journal of translational research 2020;12(5):1584-1599
Fenofibrate-induced mitochondrial dysfunction and metabolic reprogramming reversal: the anti-tumor effects in gastric carcinoma cells mediated by the PPAR pathway.
Chen L, Peng J, Wang Y, Jiang H, Wang W, Dai J, Tang M, Wei Y, Kuang H, Xu G, Xu H, Zhou F
American journal of translational research 2020;12(2):428-446
American journal of translational research 2020;12(2):428-446
Selaginellin B induces apoptosis and autophagy in pancreatic cancer cells via the JAK2/STAT3 signaling pathway.
Chu P, Wang S, Zhu X, Yang Y, Li H, Tesfaldet T, Shopit A, Yang Y, Ma X, Peng J, Tang Z, Sun Z
American journal of translational research 2020;12(11):7127-7143
American journal of translational research 2020;12(11):7127-7143
Identification of FADS1 Through Common Gene Expression Profiles for Predicting Survival in Patients with Bladder Cancer.
Jiao F, Sun H, Yang Q, Sun H, Wang Z, Liu M, Chen J
Cancer management and research 2020;12:8325-8339
Cancer management and research 2020;12:8325-8339
Blocking circ_0013912 Suppressed Cell Growth, Migration and Invasion of Pancreatic Ductal Adenocarcinoma Cells in vitro and in vivo Partially Through Sponging miR-7-5p.
Guo W, Zhao L, Wei G, Liu P, Zhang Y, Fu L
Cancer management and research 2020;12:7291-7303
Cancer management and research 2020;12:7291-7303
The Clinical Relevance and Function of Krüppel-Like Factor 16 in Breast Cancer.
Bang S, Li J, Zhang M, Cui R, Wu X, Xin Z, Ma D, Zhang J, Zhang H
Cancer management and research 2020;12:6373-6383
Cancer management and research 2020;12:6373-6383
The LINC00365/SCGB2A1 (Mammaglobin B) Axis Down-Regulates NF-κB Signaling and Is Associated with the Progression of Gastric Cancer.
Yan XY, Zhang JJ, Zhong XR, Yu SH, Xu L, Tian R, Sun LK, Su J
Cancer management and research 2020;12:621-631
Cancer management and research 2020;12:621-631
Inhibition of Skp2 Sensitizes Chronic Myeloid Leukemia Cells to Imatinib.
Chen X, Huang Z, Wu W, Xia R
Cancer management and research 2020;12:4777-4787
Cancer management and research 2020;12:4777-4787
LINC00963 Promotes Ovarian Cancer Proliferation, Migration and EMT via the miR-378g /CHI3L1 Axis.
Liu W, Yang YJ, An Q
Cancer management and research 2020;12:463-473
Cancer management and research 2020;12:463-473
Dl-3-n-Butylphthalide Promotes Remyelination and Suppresses Inflammation by Regulating AMPK/SIRT1 and STAT3/NF-κB Signaling in Chronic Cerebral Hypoperfusion.
Li M, Meng N, Guo X, Niu X, Zhao Z, Wang W, Xie X, Lv P
Frontiers in aging neuroscience 2020;12:137
Frontiers in aging neuroscience 2020;12:137
Hypoxia-induced MFAP5 Promotes Tumor Migration and Invasion via AKT Pathway in Head and Neck Squamous Cell Carcinoma.
Xu Q, Chang H, Tian X, Lou C, Ma H, Yang X
Journal of Cancer 2020;11(6):1596-1605
Journal of Cancer 2020;11(6):1596-1605
Weighted gene co-expression network analysis identifies CCNA2 as a treatment target of prostate cancer through inhibiting cell cycle.
Yang R, Du Y, Wang L, Chen Z, Liu X
Journal of Cancer 2020;11(5):1203-1211
Journal of Cancer 2020;11(5):1203-1211
miRNA-182 regulated MTSS1 inhibits proliferation and invasion in Glioma Cells.
Li Z, Zhang L, Liu Z, Huang T, Wang Y, Ma Y, Fang X, He Y, Zhou Y, Huo L, Wu J
Journal of Cancer 2020;11(19):5840-5851
Journal of Cancer 2020;11(19):5840-5851
Isoquercitrin Ameliorates Cisplatin-Induced Nephrotoxicity Via the Inhibition of Apoptosis, Inflammation, and Oxidative Stress.
Wang H, Xia W, Long G, Pei Z, Li Y, Wu M, Wang Q, Zhang Y, Jia Z, Chen H
Frontiers in pharmacology 2020;11:599416
Frontiers in pharmacology 2020;11:599416
Hydrogen Sulfide Attenuates High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease by Inhibiting Apoptosis and Promoting Autophagy via Reactive Oxygen Species/Phosphatidylinositol 3-Kinase/AKT/Mammalian Target of Rapamycin Signaling Pathway.
Wu D, Zhong P, Wang Y, Zhang Q, Li J, Liu Z, Ji A, Li Y
Frontiers in pharmacology 2020;11:585860
Frontiers in pharmacology 2020;11:585860
Integrated Analysis of Key Genes and Pathways Involved in Fetal Growth Restriction and Their Associations With the Dysregulation of the Maternal Immune System.
Wang X, Zhu H, Lei L, Zhang Y, Tang C, Wu JX, Zhou JR, Xiao XR
Frontiers in genetics 2020;11:581789
Frontiers in genetics 2020;11:581789
Mitochondrial DNA Haplogroup M7 Confers Disability in a Chinese Aging Population.
Sun D, Yao S, Wu F, Deng W, Ma Y, Jin L, Wang J, Wang X
Frontiers in genetics 2020;11:577795
Frontiers in genetics 2020;11:577795
The Human-Specific STING Agonist G10 Activates Type I Interferon and the NLRP3 Inflammasome in Porcine Cells.
Ming SL, Zeng L, Guo YK, Zhang S, Li GL, Ma YX, Zhai YY, Chang WR, Yang L, Wang J, Yang GY, Chu BB
Frontiers in immunology 2020;11:575818
Frontiers in immunology 2020;11:575818
Notoginsenoside R1 Protects Against the Acrylamide-Induced Neurotoxicity via Upregulating Trx-1-Mediated ITGAV Expression: Involvement of Autophagy.
Wang W, Huang L, Thomas ER, Hu Y, Zeng F, Li X
Frontiers in pharmacology 2020;11:559046
Frontiers in pharmacology 2020;11:559046
Fisetin Alleviated Bleomycin-Induced Pulmonary Fibrosis Partly by Rescuing Alveolar Epithelial Cells From Senescence.
Zhang L, Tong X, Huang J, Wu M, Zhang S, Wang D, Liu S, Fan H
Frontiers in pharmacology 2020;11:553690
Frontiers in pharmacology 2020;11:553690
Progesterone Regulates Glucose Metabolism Through Glucose Transporter 1 to Promote Endometrial Receptivity.
Zhang H, Qi J, Wang Y, Sun J, Li Z, Sui L, Fan J, Liu C, Shang Y, Kong L, Kong Y
Frontiers in physiology 2020;11:543148
Frontiers in physiology 2020;11:543148
Photoperiod Affects Harderian Gland Morphology and Secretion in Female Cricetulus barabensis: Autophagy, Apoptosis, and Mitochondria.
Wang Z, Xu JH, Mou JJ, Kong XT, Wu M, Xue HL, Xu LX
Frontiers in physiology 2020;11:408
Frontiers in physiology 2020;11:408
Characterization and Neuroprotection Potential of Seleno-Polymannuronate.
Bi D, Li X, Li T, Li X, Lin Z, Yao L, Li H, Xu H, Hu Z, Zhang Z, Liu Q, Xu X
Frontiers in pharmacology 2020;11:21
Frontiers in pharmacology 2020;11:21
Identification of Immune-Related Genes Contributing to the Development of Glioblastoma Using Weighted Gene Co-expression Network Analysis.
Kong Y, Feng ZC, Zhang YL, Liu XF, Ma Y, Zhao ZM, Huang B, Chen AJ, Zhang D, Thorsen F, Wang J, Yang N, Li XG
Frontiers in immunology 2020;11:1281
Frontiers in immunology 2020;11:1281
Liraglutide Ameliorates Erectile Dysfunction via Regulating Oxidative Stress, the RhoA/ROCK Pathway and Autophagy in Diabetes Mellitus.
Yuan P, Ma D, Gao X, Wang J, Li R, Liu Z, Wang T, Wang S, Liu J, Liu X
Frontiers in pharmacology 2020;11:1257
Frontiers in pharmacology 2020;11:1257
NNK-mediated upregulation of DEPDC1 stimulates the progression of oral squamous cell carcinoma by inhibiting CYP27B1 expression.
Guo J, Zhou S, Huang P, Xu S, Zhang G, He H, Zeng Y, Xu CX, Kim H, Tan Y
American journal of cancer research 2020;10(6):1745-1760
American journal of cancer research 2020;10(6):1745-1760
Novel ESCC-related gene ZNF750 as potential Prognostic biomarker and inhibits Epithelial-Mesenchymal Transition through directly depressing SNAI1 promoter in ESCC.
Kong P, Xu E, Bi Y, Xu X, Liu X, Song B, Zhang L, Cheng C, Yan T, Qian Y, Yang J, Ma Y, Cui H, Zhai Y, Zou B, Liu X, Cheng Y, Guo S, Cheng X, Cui Y
Theranostics 2020;10(4):1798-1813
Theranostics 2020;10(4):1798-1813
MicroRNA-590-3p inhibits invasion and metastasis in triple-negative breast cancer by targeting Slug.
Yan M, Ye L, Feng X, Shi R, Sun Z, Li Z, Liu T
American journal of cancer research 2020;10(3):965-974
American journal of cancer research 2020;10(3):965-974
An ultrasensitive hybridization chain reaction-amplified CRISPR-Cas12a aptasensor for extracellular vesicle surface protein quantification.
Xing S, Lu Z, Huang Q, Li H, Wang Y, Lai Y, He Y, Deng M, Liu W
Theranostics 2020;10(22):10262-10273
Theranostics 2020;10(22):10262-10273
Hsp90 inhibitor HSP990 in very low dose upregulates EAAT2 and exerts potent antiepileptic activity.
Sha L, Chen T, Deng Y, Du T, Ma K, Zhu W, Shen Y, Xu Q
Theranostics 2020;10(18):8415-8429
Theranostics 2020;10(18):8415-8429
LincRNA00494 Suppresses Non-small Cell Lung Cancer Cell Proliferation by Regulating SRCIN1 Expression as a ceRNA.
Dong J, Li B, Lin D, Lu D, Liu C, Lu X, Tang X, Li L, Zhu D, Liu J, Qiu X, Tian L, Zhou Q
Frontiers in oncology 2020;10:79
Frontiers in oncology 2020;10:79
Critical roles of microRNA-141-3p and CHD8 in hypoxia/reoxygenation-induced cardiomyocyte apoptosis.
Yao B, Wan X, Zheng X, Zhong T, Hu J, Zhou Y, Qin A, Ma Y, Yin D
Cell & bioscience 2020;10:20
Cell & bioscience 2020;10:20
Inhibition of formyl peptide receptor 1 activity suppresses tumorigenicity in vivo and attenuates the invasion and migration of lung adenocarcinoma cells under hypoxic conditions in vitro.
Huang B, Guo H, Ding J, Li J, Wang H, Xu J, Zheng Q, Zhou L, Dai Q
Annals of translational medicine 2020 Sep;8(18):1174
Annals of translational medicine 2020 Sep;8(18):1174
Effects of the linoleic acid/docosahexaenoic acid ratio and concentration inducing autophagy in Raw264.7 cells against Staphylococcus aureus.
Xu LY, Mu M, Wang ML, Liu JC, Zhou YJ, Wu J, Jiang BY, Chen MG, Hu D, Tao XR
Journal of clinical biochemistry and nutrition 2020 Sep;67(2):146-152
Journal of clinical biochemistry and nutrition 2020 Sep;67(2):146-152
Hyperbaric oxygen treatment mitigates liver damage in mice with noise exposure.
Meng X, Zhang X, Su Y, Gu Z, Xie X, Chang Y, Bao J
Clinical and experimental pharmacology & physiology 2020 Sep;47(9):1564-1574
Clinical and experimental pharmacology & physiology 2020 Sep;47(9):1564-1574
RIP1 promotes proliferation through G2/M checkpoint progression and mediates cisplatin-induced apoptosis and necroptosis in human ovarian cancer cells.
Zheng XL, Yang JJ, Wang YY, Li Q, Song YP, Su M, Li JK, Zhang L, Li ZP, Zhou B, Lin Y
Acta pharmacologica Sinica 2020 Sep;41(9):1223-1233
Acta pharmacologica Sinica 2020 Sep;41(9):1223-1233
Curcumin inhibits the growth of triple-negative breast cancer cells by silencing EZH2 and restoring DLC1 expression.
Zhou X, Jiao D, Dou M, Zhang W, Lv L, Chen J, Li L, Wang L, Han X
Journal of cellular and molecular medicine 2020 Sep;24(18):10648-10662
Journal of cellular and molecular medicine 2020 Sep;24(18):10648-10662
Cytisine attenuates bone loss of ovariectomy mouse by preventing RANKL-induced osteoclastogenesis.
Qian Z, Zhong Z, Ni S, Li D, Zhang F, Zhou Y, Kang Z, Qian J, Yu B
Journal of cellular and molecular medicine 2020 Sep;24(17):10112-10127
Journal of cellular and molecular medicine 2020 Sep;24(17):10112-10127
Pretreatment with the ALDH2 activator Alda‑1 protects rat livers from ischemia/reperfusion injury by inducing autophagy.
Liu Z, Ye S, Zhong X, Wang W, Lai CH, Yang W, Yue P, Luo J, Huang X, Zhong Z, Xiong Y, Fan X, Li L, Wang Y, Ye Q
Molecular medicine reports 2020 Sep;22(3):2373-2385
Molecular medicine reports 2020 Sep;22(3):2373-2385
Huoxuezhitong capsule ameliorates MIA-induced osteoarthritis of rats through suppressing PI3K/ Akt/ NF-κB pathway.
Ju L, Hu P, Chen P, Xue X, Li Z, He F, Qiu Z, Cheng J, Huang F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110471
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110471
GALNT2 regulates ANGPTL3 cleavage in cells and in vivo of mice.
Li X, Zhang Y, Zhang M, Wang Y
Scientific reports 2020 Sep 30;10(1):16168
Scientific reports 2020 Sep 30;10(1):16168
RNA N6-methyladenosine reader IGF2BP3 regulates cell cycle and angiogenesis in colon cancer.
Yang Z, Wang T, Wu D, Min Z, Tan J, Yu B
Journal of experimental & clinical cancer research : CR 2020 Sep 29;39(1):203
Journal of experimental & clinical cancer research : CR 2020 Sep 29;39(1):203
Ability of Post-treatment Glycyrrhizic Acid to Mitigate Cerebral Ischemia/Reperfusion Injury in Diabetic Mice.
Li Y, Yao N, Zhang T, Guo F, Niu X, Wu Z, Hou S
Medical science monitor : international medical journal of experimental and clinical research 2020 Sep 28;26:e926551
Medical science monitor : international medical journal of experimental and clinical research 2020 Sep 28;26:e926551
4-Acetylantroquinonol B Inhibits Osteoclastogenesis by Inhibiting the Autophagy Pathway in a Simulated Microgravity Model.
Wu CH, Ou CH, Yen IC, Lee SY
International journal of molecular sciences 2020 Sep 22;21(18)
International journal of molecular sciences 2020 Sep 22;21(18)
WITHDRAWN: Resveratrol partially prevents learning and memory deficits in rats exposed to gaseous formaldehyde.
Niu H, Xie R, Li L, Zhang X, Wei X, Deng J, Li Z
Environmental toxicology and pharmacology 2020 Sep 22;
Environmental toxicology and pharmacology 2020 Sep 22;
Aberrant BMP2 Signaling in Patients Diagnosed with Osteoporosis.
Durbano HW, Halloran D, Nguyen J, Stone V, McTague S, Eskander M, Nohe A
International journal of molecular sciences 2020 Sep 21;21(18)
International journal of molecular sciences 2020 Sep 21;21(18)
Cellular uptake of extracellular nucleosomes induces innate immune responses by binding and activating cGMP-AMP synthase (cGAS).
Wang H, Zang C, Ren M, Shang M, Wang Z, Peng X, Zhang Q, Wen X, Xi Z, Zhou C
Scientific reports 2020 Sep 21;10(1):15385
Scientific reports 2020 Sep 21;10(1):15385
MG53 Protects hUC-MSCs against Inflammatory Damage and Synergistically Enhances Their Efficacy in Neuroinflammation Injured Brain through Inhibiting NLRP3/Caspase-1/IL-1β Axis.
Ma S, Wang Y, Zhou X, Li Z, Zhang Z, Wang Y, Huang T, Zhang Y, Shi J, Guan F
ACS chemical neuroscience 2020 Sep 2;11(17):2590-2601
ACS chemical neuroscience 2020 Sep 2;11(17):2590-2601
NGF receptors and PI3K/AKT pathway involved in glucose fluctuation-induced damage to neurons and α-lipoic acid treatment.
Yan T, Zhang Z, Li D
BMC neuroscience 2020 Sep 17;21(1):38
BMC neuroscience 2020 Sep 17;21(1):38
Rapamycin Promotes Cardiomyocyte Differentiation of Human Induced Pluripotent Stem Cells in a Stage-Dependent Manner.
Jiang M, Liu T, Zhang J, Gao S, Tao B, Cao R, Qiu Y, Liu J, Li Y, Wang Y, Cao F
Stem cells and development 2020 Sep 15;29(18):1229-1239
Stem cells and development 2020 Sep 15;29(18):1229-1239
MicroRNA-128-1-5p attenuates myocardial ischemia/reperfusion injury by suppressing Gadd45g-mediated apoptotic signaling.
Wan X, Yao B, Ma Y, Liu Y, Tang Y, Hu J, Li M, Fu S, Zheng X, Yin D
Biochemical and biophysical research communications 2020 Sep 10;530(1):314-321
Biochemical and biophysical research communications 2020 Sep 10;530(1):314-321
Amino Acids Regulate Cisplatin Insensitivity in Neuroblastoma.
Gunda V, Pathania AS, Chava S, Prathipati P, Chaturvedi NK, Coulter DW, Pandey MK, Durden DL, Challagundla KB
Cancers 2020 Sep 10;12(9)
Cancers 2020 Sep 10;12(9)
Clusterin contributes to hepatitis C virus-related hepatocellular carcinoma by regulating autophagy.
Fu N, Du H, Li D, Lu Y, Li W, Wang Y, Kong L, Du J, Zhao S, Ren W, Han F, Wang R, Zhang Y, Nan Y
Life sciences 2020 Sep 1;256:117911
Life sciences 2020 Sep 1;256:117911
Neuronostatin Promotion Soluble Aβ1-42 Oligomers: Induced Dysfunctional Brain Glucose Metabolism in Mice.
Yang S, Zhou F, Ma M, Yuan Y, Zhao S, Yu P
Neurochemical research 2020 Oct;45(10):2474-2486
Neurochemical research 2020 Oct;45(10):2474-2486
Inhibition of TBK1 by amlexanox attenuates paraquat-induced acute lung injury.
Wang N, Li Y, Wang X, Ma Z, Wang Y, Zhang C, Yuan Y, Zhao M
Toxicology 2020 Oct;443:152555
Toxicology 2020 Oct;443:152555
miR-21a in exosomes from Lewis lung carcinoma cells accelerates tumor growth through targeting PDCD4 to enhance expansion of myeloid-derived suppressor cells.
Zhang X, Li F, Tang Y, Ren Q, Xiao B, Wan Y, Jiang S
Oncogene 2020 Oct;39(40):6354-6369
Oncogene 2020 Oct;39(40):6354-6369
ROS-mediated PERK-eIF2α-ATF4 pathway plays an important role in arsenite-induced L-02 cells apoptosis via regulating CHOP-DR5 signaling.
Liu C, Zhang A
Environmental toxicology 2020 Oct;35(10):1100-1113
Environmental toxicology 2020 Oct;35(10):1100-1113
Protective effects of isorhamnetin on pulmonary arterial hypertension: in vivo and in vitro studies.
Chang Z, Wang JL, Jing ZC, Ma P, Xu QB, Na JR, Tian J, Ma X, Zhou W, Zhou R
Phytotherapy research : PTR 2020 Oct;34(10):2730-2744
Phytotherapy research : PTR 2020 Oct;34(10):2730-2744
Melatonin synergizes BRAF-targeting agent dabrafenib for the treatment of anaplastic thyroid cancer by inhibiting AKT/hTERT signalling.
Liao Y, Gao Y, Chang A, Li Z, Wang H, Cao J, Gu W, Tang R
Journal of cellular and molecular medicine 2020 Oct;24(20):12119-12130
Journal of cellular and molecular medicine 2020 Oct;24(20):12119-12130
Effect of autophagy on irradiation‑induced damage in osteoblast‑like MC3T3‑E1 cells.
Li R, Yang W, Hu X, Zhou D, Huang K, Wang C, Li Y, Liu B
Molecular medicine reports 2020 Oct;22(4):3473-3481
Molecular medicine reports 2020 Oct;22(4):3473-3481
STAT3-PTTG11 abrogation inhibits proliferation and induces apoptosis in malignant glioma cells.
Cui L, Xu L, Wang G, Wen J, Luo L, Zhao H, Chen S, Zheng M, Sun C, Jin X, Yang L
Oncology letters 2020 Oct;20(4):6
Oncology letters 2020 Oct;20(4):6
SLC25A10 performs an oncogenic role in human osteosarcoma.
Wang G, Xia J, Chen C, Qiu J, Sun P, Peng Z, Chen X, Xu B
Oncology letters 2020 Oct;20(4):2
Oncology letters 2020 Oct;20(4):2
Involvement of p53 Acetylation in Growth Suppression of Cutaneous T-Cell Lymphomas Induced by HDAC Inhibition.
Yu X, Li H, Zhu M, Hu P, Liu X, Qing Y, Wang X, Wang H, Wang Z, Xu J, Tan R, Guo Q, Hui H
The Journal of investigative dermatology 2020 Oct;140(10):2009-2022.e4
The Journal of investigative dermatology 2020 Oct;140(10):2009-2022.e4
DUSP5 (dual-specificity protein phosphatase 5) suppresses BCG-induced autophagy via ERK 1/2 signaling pathway.
Luo J, Xue D, Song F, Liu X, Li W, Wang Y
Molecular immunology 2020 Oct;126:101-109
Molecular immunology 2020 Oct;126:101-109
N-Ethyl-2-Pyrrolidinone-Substituted Flavan-3-Ols with Anti-inflammatory Activity in Lipopolysaccharide-Stimulated Macrophages Are Storage-Related Marker Compounds for Green Tea.
Dai W, Lou N, Xie D, Hu Z, Song H, Lu M, Shang D, Wu W, Peng J, Yin P, Lin Z
Journal of agricultural and food chemistry 2020 Oct 28;68(43):12164-12172
Journal of agricultural and food chemistry 2020 Oct 28;68(43):12164-12172
Regulatory coupling between long noncoding RNAs and senescence in irradiated microglia.
Xu A, Li R, Ren A, Jian H, Huang Z, Zeng Q, Wang B, Zheng J, Chen X, Zheng N, Zheng R, Tian Y, Liu M, Mao Z, Ji A, Yuan Y
Journal of neuroinflammation 2020 Oct 28;17(1):321
Journal of neuroinflammation 2020 Oct 28;17(1):321
Novel mechanisms underlying anti-polycystic ovary like syndrome effects of electroacupuncture in rats: suppressing SREBP1 to mitigate insulin resistance, mitochondrial dysfunction and oxidative stress.
Peng Y, Yang X, Luo X, Liu C, Cao X, Wang H, Guo L
Biological research 2020 Oct 27;53(1):50
Biological research 2020 Oct 27;53(1):50
Impaired mitochondrial medium-chain fatty acid oxidation drives periportal macrovesicular steatosis in sirtuin-5 knockout mice.
Goetzman ES, Bharathi SS, Zhang Y, Zhao XJ, Dobrowolski SF, Peasley K, Sims-Lucas S, Monga SP
Scientific reports 2020 Oct 27;10(1):18367
Scientific reports 2020 Oct 27;10(1):18367
HOTAIR maintains the stemness of ovarian cancer stem cells via the miR-206/TBX3 axis.
Zhang Y, Guo J, Cai E, Cai J, Wen Y, Lu S, Li X, Han Q, Jiang J, Li T, Wang Z
Experimental cell research 2020 Oct 15;395(2):112218
Experimental cell research 2020 Oct 15;395(2):112218
Hepatoprotective effects of Di Wu Yang Gan: A medicinal food against CCl(4)-induced hepatotoxicity in vivo and in vitro.
Xu W, Xiao M, Li J, Chen Y, Sun Q, Li H, Sun W
Food chemistry 2020 Oct 15;327:127093
Food chemistry 2020 Oct 15;327:127093
Protective effects of pterostilbene against hepatic damage, redox imbalance, mitochondrial dysfunction, and endoplasmic reticulum stress in weanling piglets.
Zhang H, Chen Y, Li Y, Jia P, Ji S, Chen Y, Wang T
Journal of animal science 2020 Oct 1;98(10)
Journal of animal science 2020 Oct 1;98(10)
Nrf2 activation protects auditory hair cells from cisplatin-induced ototoxicity independent on mitochondrial ROS production.
Zhang W, Xiong H, Pang J, Su Z, Lai L, Lin H, Jian B, He W, Yang H, Zheng Y
Toxicology letters 2020 Oct 1;331:1-10
Toxicology letters 2020 Oct 1;331:1-10
Effect of Combined Sorafenib/Cisplatinum Treatment on the Autophagy and Proliferation of Hepatocellular Carcinoma hepG2 Cells in Vitro.
Wang Y, Wang L
Asian Pacific journal of cancer prevention : APJCP 2020 Oct 1;21(10):2853-2857
Asian Pacific journal of cancer prevention : APJCP 2020 Oct 1;21(10):2853-2857
Treatment with 5-methoxytryptophan attenuates microglia-induced neuroinflammation in spinal cord trauma.
Hong X, Jiang F, Li Y, Fang L, Qian Z, Chen H, Kong R
International immunopharmacology 2020 Nov;88:106988
International immunopharmacology 2020 Nov;88:106988
Echinacea polysaccharide alleviates LPS-induced lung injury via inhibiting inflammation, apoptosis and activation of the TLR4/NF-κB signal pathway.
Zhang H, Lang W, Wang S, Li B, Li G, Shi Q
International immunopharmacology 2020 Nov;88:106974
International immunopharmacology 2020 Nov;88:106974
Panax notoginseng saponin R1 modulates TNF-α/NF-κB signaling and attenuates allergic airway inflammation in asthma.
Xue K, Ruan L, Hu J, Fu Z, Tian D, Zou W
International immunopharmacology 2020 Nov;88:106860
International immunopharmacology 2020 Nov;88:106860
LMCD1 antisense RNA 1 (LMCD1-AS1) potentiates thyroid cancer cell growth and stemness via a positive feedback loop of LMCD1-AS1/miR-1287-5p/GLI2.
Shao J, Xu Y, Li H, Chen L, Wang W, Shen D, Chen J
Annals of translational medicine 2020 Nov;8(22):1508
Annals of translational medicine 2020 Nov;8(22):1508
PKCβ/NF-κB pathway in diabetic atrial remodeling.
Wang H, Xu Y, Xu A, Wang X, Cheng L, Lee S, Tse G, Li G, Liu T, Fu H
Journal of physiology and biochemistry 2020 Nov;76(4):637-653
Journal of physiology and biochemistry 2020 Nov;76(4):637-653
Induction of SPARC on Oxidative Stress, Inflammatory Phenotype Transformation, and Apoptosis of Human Brain Smooth Muscle Cells Via TGF-β1-NOX4 Pathway.
Tan X, Li T, Zhu S, Zhong W, Li F, Wang Y
Journal of molecular neuroscience : MN 2020 Nov;70(11):1728-1741
Journal of molecular neuroscience : MN 2020 Nov;70(11):1728-1741
Lamin B1 deficiency promotes malignancy and predicts poor prognosis in gastric cancer.
Yu ZY, Jiang XY, Zhao RR, Luo CJ, Ren YX, Ma ZJ, Ye HL, Shi WG, Wang C, Jiao ZY
Neoplasma 2020 Nov;67(6):1303-1313
Neoplasma 2020 Nov;67(6):1303-1313
MicroRNA-145 suppresses osteogenic differentiation of human jaw bone marrow mesenchymal stem cells partially via targeting semaphorin 3A.
Jin Y, Hong F, Bao Q, Xu Q, Duan R, Zhu Z, Zhang W, Ma C
Connective tissue research 2020 Nov;61(6):577-585
Connective tissue research 2020 Nov;61(6):577-585
HIF-1α ameliorates tubular injury in diabetic nephropathy via HO-1-mediated control of mitochondrial dynamics.
Jiang N, Zhao H, Han Y, Li L, Xiong S, Zeng L, Xiao Y, Wei L, Xiong X, Gao P, Yang M, Liu Y, Sun L
Cell proliferation 2020 Nov;53(11):e12909
Cell proliferation 2020 Nov;53(11):e12909
miR-124-3p increases in high glucose induced osteocyte-derived exosomes and regulates galectin-3 expression: A possible mechanism in bone remodeling alteration in diabetic periodontitis.
Li J, Guo Y, Chen YY, Liu Q, Chen Y, Tan L, Zhang SH, Gao ZR, Zhou YH, Zhang GY, Feng YZ
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Nov;34(11):14234-14249
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Nov;34(11):14234-14249
Pharmacological Effects of Fasudil on Flap Survival in a Rodent Model.
Ji E, Wang J, Wang L, Pan Z, Gao W
The Journal of surgical research 2020 Nov;255:575-582
The Journal of surgical research 2020 Nov;255:575-582
Exosomes derived from smooth muscle cells ameliorate diabetes-induced erectile dysfunction by inhibiting fibrosis and modulating the NO/cGMP pathway.
Song J, Sun T, Tang Z, Ruan Y, Liu K, Rao K, Lan R, Wang S, Wang T, Liu J
Journal of cellular and molecular medicine 2020 Nov;24(22):13289-13302
Journal of cellular and molecular medicine 2020 Nov;24(22):13289-13302
Endoplasmic reticulum stress remodels alveolar bone formation after tooth extraction.
Chen Y, Guo Y, Li J, Chen YY, Liu Q, Tan L, Gao ZR, Zhang SH, Zhou YH, Feng YZ
Journal of cellular and molecular medicine 2020 Nov;24(21):12411-12420
Journal of cellular and molecular medicine 2020 Nov;24(21):12411-12420
Downregulation of HDAC1 suppresses media degeneration by inhibiting the migration and phenotypic switch of aortic vascular smooth muscle cells in aortic dissection.
Sun L, Wang C, Yuan Y, Guo Z, He Y, Ma W, Zhang J
Journal of cellular physiology 2020 Nov;235(11):8747-8756
Journal of cellular physiology 2020 Nov;235(11):8747-8756
Insulin Promotes Corneal Nerve Repair and Wound Healing in Type 1 Diabetic Mice by Enhancing Wnt/β-Catenin Signaling.
Yang S, Zhang Y, Zhang Z, Dan J, Zhou Q, Wang X, Li W, Zhou L, Yang L, Xie L
The American journal of pathology 2020 Nov;190(11):2237-2250
The American journal of pathology 2020 Nov;190(11):2237-2250
Genkwadaphnin inhibits growth and invasion in hepatocellular carcinoma by blocking DHCR24-mediated cholesterol biosynthesis and lipid rafts formation.
Wu J, Guo L, Qiu X, Ren Y, Li F, Cui W, Song S
British journal of cancer 2020 Nov;123(11):1673-1685
British journal of cancer 2020 Nov;123(11):1673-1685
Deficiency of pseudogene UPAT leads to hepatocellular carcinoma progression and forms a positive feedback loop with ZEB1.
Xiang L, Huang X, Wang S, Ou H, Chen Z, Hu Z, Huang Y, Li X, Yuan Y, Yang D
Cancer science 2020 Nov;111(11):4102-4117
Cancer science 2020 Nov;111(11):4102-4117
miRNA-122-5p stimulates the proliferation and DNA synthesis and inhibits the early apoptosis of human spermatogonial stem cells by targeting CBL and competing with lncRNA CASC7.
Zhou F, Chen W, Cui Y, Liu B, Yuan Q, Li Z, He Z
Aging 2020 Nov 24;12(24):25528-25546
Aging 2020 Nov 24;12(24):25528-25546
Liver Expression of IGF2 and Related Proteins in ZBED6 Gene-Edited Pig by RNA-Seq.
Zhao H, Wu M, Liu S, Tang X, Yi X, Li Q, Wang S, Sun X
Animals : an open access journal from MDPI 2020 Nov 22;10(11)
Animals : an open access journal from MDPI 2020 Nov 22;10(11)
miR-100-3p inhibits the adipogenic differentiation of hMSCs by targeting PIK3R1 via the PI3K/AKT signaling pathway.
Wang T, Zhong D, Qin Z, He S, Gong Y, Li W, Li X
Aging 2020 Nov 20;12(24):25090-25100
Aging 2020 Nov 20;12(24):25090-25100
HMGB1 mediates homocysteine-induced endothelial cells pyroptosis via cathepsin V-dependent pathway.
Leng Y, Chen R, Chen R, He S, Shi X, Zhou X, Zhang Z, Chen AF
Biochemical and biophysical research communications 2020 Nov 19;532(4):640-646
Biochemical and biophysical research communications 2020 Nov 19;532(4):640-646
Polysaccharides from Armillariella tabescens mycelia ameliorate insulin resistance in type 2 diabetic mice.
Yang R, Li Y, Cai J, Ji J, Wang Y, Zhang W, Pan W, Chen Y
Food & function 2020 Nov 18;11(11):9675-9685
Food & function 2020 Nov 18;11(11):9675-9685
Vernonia patula (Dryand.) Merr. and Leucas chinensis (Retz.) R. Brown exert anti-inflammatory activities and relieve oxidative stress via Nrf2 activation.
Wu PS, Jeng J, Yang JJ, Kao V, Yen JH, Wu MJ
Journal of ethnopharmacology 2020 Nov 15;262:113155
Journal of ethnopharmacology 2020 Nov 15;262:113155
Lysine acetylation of F-actin decreases tropomyosin-based inhibition of actomyosin activity.
Schmidt W, Madan A, Foster DB, Cammarato A
The Journal of biological chemistry 2020 Nov 13;295(46):15527-15539
The Journal of biological chemistry 2020 Nov 13;295(46):15527-15539
Oral recombinant methioninase increases TRAIL receptor-2 expression to regress pancreatic cancer in combination with agonist tigatuzumab in an orthotopic mouse model.
Yamamoto J, Miyake K, Han Q, Tan Y, Inubushi S, Sugisawa N, Higuchi T, Tashiro Y, Nishino H, Homma Y, Matsuyama R, Chawla SP, Bouvet M, Singh SR, Endo I, Hoffman RM
Cancer letters 2020 Nov 1;492:174-184
Cancer letters 2020 Nov 1;492:174-184
Artesunate induces autophagy dependent apoptosis through upregulating ROS and activating AMPK-mTOR-ULK1 axis in human bladder cancer cells.
Zhou X, Chen Y, Wang F, Wu H, Zhang Y, Liu J, Cai Y, Huang S, He N, Hu Z, Jin X
Chemico-biological interactions 2020 Nov 1;331:109273
Chemico-biological interactions 2020 Nov 1;331:109273
Differential distribution and potential regulatory roles of estrogen receptor 2a and 2b in the pituitary of ricefield eel Monopterus albus.
Zheng Z, Liu M, Meng F, Zhang W, Zhang L
General and comparative endocrinology 2020 Nov 1;298:113554
General and comparative endocrinology 2020 Nov 1;298:113554
Norcantharidin protects against renal interstitial fibrosis by suppressing TWEAK-mediated Smad3 phosphorylation.
Zeng D, Xiao Z, Xu Q, Luo H, Wen L, Tang C, Shan Y, Tian J, Wei J, Li Y
Life sciences 2020 Nov 1;260:118488
Life sciences 2020 Nov 1;260:118488
Anti-neuroinflammatory effect of 3,4-dihydroxybenzaldehyde in ischemic stroke.
Li X, Xiang B, Shen T, Xiao C, Dai R, He F, Lin Q
International immunopharmacology 2020 May;82:106353
International immunopharmacology 2020 May;82:106353
The B7-H4 gene induces immune escape partly via upregulating the PD-1/Stat3 pathway in non-small cell lung cancer.
Yuan L, Ye J, Fan D
Human immunology 2020 May;81(5):254-261
Human immunology 2020 May;81(5):254-261
Protective effect of Berberine on reproductive function and spermatogenesis in diabetic rats via inhibition of ROS/JAK2/NFκB pathway.
Song J, Gao X, Tang Z, Li H, Ruan Y, Liu Z, Wang T, Wang S, Liu J, Jiang H
Andrology 2020 May;8(3):793-806
Andrology 2020 May;8(3):793-806
Cannabinoid receptor 2 activation alleviates septic lung injury by promoting autophagy via inhibition of inflammatory mediator release.
Liu AP, Yuan QH, Zhang B, Yang L, He QW, Chen K, Liu QS, Li Z, Zhan J
Cellular signalling 2020 May;69:109556
Cellular signalling 2020 May;69:109556
miR-362 knock-down promotes proliferation and inhibits apoptosis in porcine immature Sertoli cells by targeting the RMI1 gene.
Ran M, Luo H, Gao H, Tang X, Chen Y, Zeng X, Weng B, Chen B
Reproduction in domestic animals = Zuchthygiene 2020 May;55(5):547-558
Reproduction in domestic animals = Zuchthygiene 2020 May;55(5):547-558
miR‑95 promotes osteosarcoma growth by targeting SCNN1A.
Geng Y, Zhao S, Jia Y, Xia G, Li H, Fang Z, Zhang Q, Tian R
Oncology reports 2020 May;43(5):1429-1436
Oncology reports 2020 May;43(5):1429-1436
Establishment and characterization of an immortalized human chondrocyte cell line.
Yang J, Tang Y, Chen W, Zhang M, Hong F, Yang D, Bao Q, Yang Y, Jin Y, Li L, Ma C
Biotechnology letters 2020 May;42(5):707-716
Biotechnology letters 2020 May;42(5):707-716
Characterization of a Novel Interleukin-1 Receptor Antagonist from Sheep (Ovis aries).
Zhang SJ, Guo X, Hu P, Lu SY, Liu NN, Fu BQ, Wang N, Li YS, Wang LL, Chang J, Chang HZ, Liu ZS, Zhou Y, Ren HL
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2020 May;40(5):268-278
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2020 May;40(5):268-278
Relevance research between the expression of p16(INK4a) , Notch1, and hTERC genes: The development of HPV16-positive cervical cancer.
Huo W, Zhai S, Wang Y, Qiang X, Na R, Gui H, Wu N, Cao Y, Bai H
Journal of clinical laboratory analysis 2020 May;34(5):e23207
Journal of clinical laboratory analysis 2020 May;34(5):e23207
The role of PSMB5 in sodium arsenite-induced oxidative stress in L-02 cells.
Lv Y, Hu Q, Shi M, Wang W, Zheng Y, Yang Z, Peng L, Bi D, Zhang A, Hu Y
Cell stress & chaperones 2020 May;25(3):533-540
Cell stress & chaperones 2020 May;25(3):533-540
MiR-145-5p alleviates hypoxia/reoxygenation- induced cardiac microvascular endothelial cell injury in coronary heart disease by inhibiting Smad4 expression.
Li LL, Mao CD, Wang GP, Wang N, Xue AG
European review for medical and pharmacological sciences 2020 May;24(9):5008-5017
European review for medical and pharmacological sciences 2020 May;24(9):5008-5017
AMPK-mTOR-ULK1 axis activation-dependent autophagy promotes hydroxycamptothecin-induced apoptosis in human bladder cancer cells.
Wang F, Cao M, Fan M, Wu H, Huang W, Zhang Y, Hu Z, Jin X
Journal of cellular physiology 2020 May;235(5):4302-4315
Journal of cellular physiology 2020 May;235(5):4302-4315
Porcine parvovirus nonstructural protein NS1 activates NF-κB and it involves TLR2 signaling pathway.
Jin X, Yuan Y, Zhang C, Zhou Y, Song Y, Wei Z, Zhang G
Journal of veterinary science 2020 May;21(3):e50
Journal of veterinary science 2020 May;21(3):e50
Leptin mediates protection of hydrogen sulfide against 6-hydroxydopamine-induced Parkinson's disease: Involving enhancement in Warburg effect.
Yang SQ, Tian Q, Li D, He SQ, Hu M, Liu SY, Zou W, Chen YJ, Zhang P, Tang XQ
Neurochemistry international 2020 May;135:104692
Neurochemistry international 2020 May;135:104692
Expression and distribution of bone morphogenetic protein 4 and its antagonist Noggin in the skin of Kazakh sheep (Ovis aries) with a white and brown coat color.
Sun X, Qu G, Wang D, Wang T, Sai W, Chen Y, Yuan L, Pang Q
Acta histochemica 2020 May;122(4):151539
Acta histochemica 2020 May;122(4):151539
ROS enhances the cytotoxicity of cisplatin by inducing apoptosis and autophagy in tongue squamous cell carcinoma cells.
Xue DF, Pan ST, Huang G, Qiu JX
The international journal of biochemistry & cell biology 2020 May;122:105732
The international journal of biochemistry & cell biology 2020 May;122:105732
Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.
Li Y, Tang L, Yue J, Gou X, Lin A, Weatherbee SD, Wu X
EMBO reports 2020 May 6;21(5):e48566
EMBO reports 2020 May 6;21(5):e48566
High glucose inhibits vascular endothelial Keap1/Nrf2/ARE signal pathway via downregulation of monomethyltransferase SET8 expression.
Chen X, Qi J, Wu Q, Jiang H, Wang J, Chen W, Mao A, Zhu M
Acta biochimica et biophysica Sinica 2020 May 26;52(5):506-516
Acta biochimica et biophysica Sinica 2020 May 26;52(5):506-516
Effects of inhalation of sevoflurane at different concentrations on TRPV1 in airways of rats at different developmental stages.
Liu D, Yuan J, Fei X, Zhu Y, Zhou Y, Zhang C, Dong L, Zhu Z
Life sciences 2020 May 15;249:117472
Life sciences 2020 May 15;249:117472
Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype.
Hou B, Zhang Y, Liang P, He Y, Peng B, Liu W, Han S, Yin J, He X
Cell death & disease 2020 May 15;11(5):377
Cell death & disease 2020 May 15;11(5):377
LncRNA TROJAN promotes proliferation and resistance to CDK4/6 inhibitor via CDK2 transcriptional activation in ER+ breast cancer.
Jin X, Ge LP, Li DQ, Shao ZM, Di GH, Xu XE, Jiang YZ
Molecular cancer 2020 May 11;19(1):87
Molecular cancer 2020 May 11;19(1):87
Overexpression of endogenous lipoic acid synthase attenuates pulmonary fibrosis induced by crystalline silica in mice.
Zhao Y, Xu G, Li H, Chang M, Guan Y, Li Y, Wu W, Yao S
Toxicology letters 2020 May 1;323:57-66
Toxicology letters 2020 May 1;323:57-66
Spinosin Inhibits Aβ(1-42) Production and Aggregation via Activating Nrf2/HO-1 Pathway.
Zhang X, Wang J, Gong G, Ma R, Xu F, Yan T, Wu B, Jia Y
Biomolecules & therapeutics 2020 May 1;28(3):259-266
Biomolecules & therapeutics 2020 May 1;28(3):259-266
Association analysis of DNA methyltransferases in IgA nephropathy.
Xia M, Chen G, Liu D, Tang X, Liu Y, Wu L, Liu Y, Liu H
International immunopharmacology 2020 Mar;80:106147
International immunopharmacology 2020 Mar;80:106147
Role of PEPT1in the transport of cinnabar in Caco-2 cells.
Wu Q, He X, Zhou S, Shi F, Lu Y
Toxicology in vitro : an international journal published in association with BIBRA 2020 Mar;63:104747
Toxicology in vitro : an international journal published in association with BIBRA 2020 Mar;63:104747
Ginsenoside protects against AKI via activation of HIF‑1α and VEGF‑A in the kidney‑brain axis.
Mao H, Jiang C, Xu L, Chen D, Liu H, Xu Y, Ma K, Wang M
International journal of molecular medicine 2020 Mar;45(3):939-946
International journal of molecular medicine 2020 Mar;45(3):939-946
MTFP1 overexpression promotes the growth of oral squamous cell carcinoma by inducing ROS production.
Xiao T, Sun J, Xing Z, Xie F, Yang L, Ding W
Cell biology international 2020 Mar;44(3):821-829
Cell biology international 2020 Mar;44(3):821-829
Soluble Uric Acid Promotes Atherosclerosis via AMPK (AMP-Activated Protein Kinase)-Mediated Inflammation.
Kimura Y, Yanagida T, Onda A, Tsukui D, Hosoyamada M, Kono H
Arteriosclerosis, thrombosis, and vascular biology 2020 Mar;40(3):570-582
Arteriosclerosis, thrombosis, and vascular biology 2020 Mar;40(3):570-582
Sodium butyrate inhibits migration and induces AMPK-mTOR pathway-dependent autophagy and ROS-mediated apoptosis via the miR-139-5p/Bmi-1 axis in human bladder cancer cells.
Wang F, Wu H, Fan M, Yu R, Zhang Y, Liu J, Zhou X, Cai Y, Huang S, Hu Z, Jin X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4266-4282
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4266-4282
Guizhi Decoction () Inhibits Cholinergic Transdifferentiation by Regulating Imbalance of NGF and LIF in Salt-Sensitive Hypertensive Heart Failure Rats.
Wang YC, Ma DF, Jiang P, Zhang YM, Zhou GF, Yang JL, Li ZY, Li X
Chinese journal of integrative medicine 2020 Mar;26(3):188-196
Chinese journal of integrative medicine 2020 Mar;26(3):188-196
Hyperthermic intraperitoneal chemotherapy with recombinant mutant human TNF-α and raltitrexed in mice with colorectal-peritoneal carcinomatosis.
Gong Q, Song C, Wang X, Wang R, Cai G, Liang X, Liu J
Experimental biology and medicine (Maywood, N.J.) 2020 Mar;245(6):542-551
Experimental biology and medicine (Maywood, N.J.) 2020 Mar;245(6):542-551
Prenatal hypoxia inhibited propionate-evoked BK channels of mesenteric artery smooth muscle cells in offspring.
Zhang W, Feng X, Zhang Y, Sun M, Li L, Gao Q, Tang J, Zhang P, Lv J, Zhou X, Xu Z
Journal of cellular and molecular medicine 2020 Mar;24(5):3192-3202
Journal of cellular and molecular medicine 2020 Mar;24(5):3192-3202
LncRNA MALAT1 knockdown inhibits cell migration and invasion by suppressing autophagy through miR-384/GOLM1 axis in glioma.
Ma R, Zhang BW, Zhang ZB, Deng QJ
European review for medical and pharmacological sciences 2020 Mar;24(5):2601-2615
European review for medical and pharmacological sciences 2020 Mar;24(5):2601-2615
The Immunomodulatory Effects and Mechanisms of Tim-3 Action in the Early Stage of Mice with Severe Acute Pancreatitis.
Lin M, Huang J, Chen WC, Fan ZN, Qin X
Iranian journal of immunology : IJI 2020 Mar;17(1):52-63
Iranian journal of immunology : IJI 2020 Mar;17(1):52-63
Protein microarray analysis of cytokine expression changes in distal stumps after sciatic nerve transection.
Cheng XQ, Liang XZ, Wei S, Ding X, Han GH, Liu P, Sun X, Quan Q, Tang H, Zhao Q, Shang AJ, Peng J
Neural regeneration research 2020 Mar;15(3):503-511
Neural regeneration research 2020 Mar;15(3):503-511
CADM1 inhibits ovarian cancer cell proliferation and migration by potentially regulating the PI3K/Akt/mTOR pathway.
Si X, Xu F, Xu F, Wei M, Ge Y, Chenge S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109717
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109717
Metformin alleviates breast cancer through targeting high-mobility group AT-hook 2.
Li Y, Wang D, Ren H, Feng W
Thoracic cancer 2020 Mar;11(3):686-692
Thoracic cancer 2020 Mar;11(3):686-692
circFOXM1 promotes proliferation of non-small cell lung carcinoma cells by acting as a ceRNA to upregulate FAM83D.
Yu C, Cheng Z, Cui S, Mao X, Li B, Fu Y, Wang H, Jin H, Ye Q, Zhao X, Jiang L, Qin W
Journal of experimental & clinical cancer research : CR 2020 Mar 30;39(1):55
Journal of experimental & clinical cancer research : CR 2020 Mar 30;39(1):55
Role of autophagy and apoptosis in atrophic epithelium in oral submucous fibrosis.
Zhu B, Jiang Q, Que G, Dai Z, Wu Y
Journal of oral science 2020 Mar 28;62(2):184-188
Journal of oral science 2020 Mar 28;62(2):184-188
The mechanism and role of intracellular α-ketoglutarate reduction in hepatic stellate cell activation.
Zhao J, Jiang Y, Sun X, Liu X, Liu F, Song M, Zhang L
Bioscience reports 2020 Mar 27;40(3)
Bioscience reports 2020 Mar 27;40(3)
Connective tissue growth factor as an unfavorable prognostic marker promotes the proliferation, migration, and invasion of gliomas.
Song ZB, Yang HP, Xu AQ, Zhan ZM, Song Y, Li ZY
Chinese medical journal 2020 Mar 20;133(6):670-678
Chinese medical journal 2020 Mar 20;133(6):670-678
The Late Domain of Prototype Foamy Virus Gag Facilitates Autophagic Clearance of Stress Granules by Promoting Amphisome Formation.
Zheng Y, Zhu G, Yan J, Tang Y, Han S, Yin J, Peng B, He X, Liu W
Journal of virology 2020 Mar 17;94(7)
Journal of virology 2020 Mar 17;94(7)
Critical role of toll-like receptor 4 (TLR4) in ricin toxin-induced inflammatory responses in macrophages.
Dong M, Yu H, Wang Y, Sun C, Chang Y, Yin Q, Zhao G, Xu N, Liu W
Toxicology letters 2020 Mar 15;321:54-60
Toxicology letters 2020 Mar 15;321:54-60
Monocyte-derived extracellular vesicles upon treated by palmitate promote endothelial migration and monocytes attachment to endothelial cells.
Gao W, Guo X, Wang Y, Jian D, Li M
Biochemical and biophysical research communications 2020 Mar 12;523(3):685-691
Biochemical and biophysical research communications 2020 Mar 12;523(3):685-691
Transgelin-2 contributes to proliferation and progression of hepatocellular carcinoma via regulating Annexin A2.
Shi J, Ren M, She X, Zhang Z, Zhao Y, Han Y, Lu D, Lyu L
Biochemical and biophysical research communications 2020 Mar 12;523(3):632-638
Biochemical and biophysical research communications 2020 Mar 12;523(3):632-638
Effect of NF-κB signal pathway on mucus secretion induced by atmospheric PM(2.5) in asthmatic rats.
Liu Y, Zhang B, Zhang T, Wang H, Peng L, Zhou L
Ecotoxicology and environmental safety 2020 Mar 1;190:110094
Ecotoxicology and environmental safety 2020 Mar 1;190:110094
Club cell 10-kDa protein (CC10) inhibits cPLA2/COX2 pathway to alleviate RSV-induced airway inflammation and AHR.
Yu G, Mo S, Gao L, Wen X, Chen S, Long X, Xie X, Deng Y, Ren L, Zang N, Chen S, Liu E
International immunopharmacology 2020 Jun;83:106327
International immunopharmacology 2020 Jun;83:106327
Microglia polarization of hippocampus is involved in the mechanism of Apelin-13 ameliorating chronic water immersion restraint stress-induced depression-like behavior in rats.
Zhou S, Chen S, Xie W, Guo X, Zhao J
Neuropeptides 2020 Jun;81:102006
Neuropeptides 2020 Jun;81:102006
Dihydromethysticin, a natural molecule from Kava, suppresses the growth of colorectal cancer via the NLRC3/PI3K pathway.
Pan H, Liu F, Wang J, Zhao M, Wang D, Jia C, Wang T, Chen Z, Fan Y, Liang D, Meng Q
Molecular carcinogenesis 2020 Jun;59(6):575-589
Molecular carcinogenesis 2020 Jun;59(6):575-589
Obesity induces preadipocyte CD36 expression promoting inflammation via the disruption of lysosomal calcium homeostasis and lysosome function.
Luo X, Li Y, Yang P, Chen Y, Wei L, Yu T, Xia J, Ruan XZ, Zhao L, Chen Y
EBioMedicine 2020 Jun;56:102797
EBioMedicine 2020 Jun;56:102797
Effects of cisplatin on the proliferation, invasion and apoptosis of breast cancer cells following β‑catenin silencing.
Zhu X, Feng J, Fu W, Shu X, Wan X, Liu J
International journal of molecular medicine 2020 Jun;45(6):1838-1850
International journal of molecular medicine 2020 Jun;45(6):1838-1850
Compositional characterization of Pyrus ussuriensis Maxim and their antioxidant activities and induction of apoptosis in Bel-7402 cell.
Peng F, Li G, Xie Y, Yin HY, Li XJ, Yang YD
Journal of food biochemistry 2020 Jun;44(6):e13222
Journal of food biochemistry 2020 Jun;44(6):e13222
Alda-1, an Aldehyde Dehydrogenase 2 Agonist, Improves Cutaneous Wound Healing by Activating Epidermal Keratinocytes via Akt/GSK-3β/β-Catenin Pathway.
Zhang S, Chen C, Ying J, Wei C, Wang L, Yang Z, Qi F
Aesthetic plastic surgery 2020 Jun;44(3):993-1005
Aesthetic plastic surgery 2020 Jun;44(3):993-1005
Protein Phosphatase 2A Inhibiting β-Catenin Phosphorylation Contributes Critically to the Anti-renal Interstitial Fibrotic Effect of Norcantharidin.
Xiao Z, Wen L, Zeng D, Yin D, Zhou X, Tang C, Li Y
Inflammation 2020 Jun;43(3):878-891
Inflammation 2020 Jun;43(3):878-891
Neuroprotective effects of notoginsenoside R1 by upregulating Trx-1 on acrylamide-induced neurotoxicity in PC12.
Wang W, Huang L, Hu Y, Thomas ER, Li X
Human & experimental toxicology 2020 Jun;39(6):797-807
Human & experimental toxicology 2020 Jun;39(6):797-807
Hispidulin Inhibits Neuroinflammation in Lipopolysaccharide-Activated BV2 Microglia and Attenuates the Activation of Akt, NF-κB, and STAT3 Pathway.
Yu CI, Cheng CI, Kang YF, Chang PC, Lin IP, Kuo YH, Jhou AJ, Lin MY, Chen CY, Lee CH
Neurotoxicity research 2020 Jun;38(1):163-174
Neurotoxicity research 2020 Jun;38(1):163-174
CAFs-derived MFAP5 promotes bladder cancer malignant behavior through NOTCH2/HEY1 signaling.
Zhou Z, Cui D, Sun MH, Huang JL, Deng Z, Han BM, Sun XW, Xia SJ, Sun F, Shi F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):7970-7988
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):7970-7988
Effect of STAT3 mediated epigenetic regulation in pre-eclampsia: an analysis of trial data.
Zhang XL, Pan J, Wang G, Li H, Wang JL, Jiang XM, Zhao XY
European review for medical and pharmacological sciences 2020 Jun;24(11):5843-5855
European review for medical and pharmacological sciences 2020 Jun;24(11):5843-5855
Triiodothyronine potentiates angiogenesis-related factor expression through PI3K/AKT signaling pathway in human osteoarthritic osteoblasts.
Li L, Pang Y, Zhang L, Li M, Zhu C, Fang S, Yin Z
Iranian journal of basic medical sciences 2020 Jun;23(6):819-825
Iranian journal of basic medical sciences 2020 Jun;23(6):819-825
Correction of Bcl-x splicing improves responses to imatinib in chronic myeloid leukaemia cells and mouse models.
Zhang J, Wang Y, Li SQ, Fang L, Wang XZ, Li J, Zhang HB, Huang B, Xu YM, Yang WM, Lin J, Min QH, Liao ZH, Wu Y, Liu J
British journal of haematology 2020 Jun;189(6):1141-1150
British journal of haematology 2020 Jun;189(6):1141-1150
Tubeimoside I improves survival of mice in sepsis by inhibiting inducible nitric oxide synthase expression.
Luo M, Luo S, Cheng Z, Yang X, Lv D, Li X, Guo Y, Li C, Yan J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110083
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110083
CD4(+) T cells and TGFβ1/MAPK signal pathway involved in the valvular hyperblastosis and fibrosis in patients with rheumatic heart disease.
Zhao Z, He D, Ling F, Chu T, Huang D, Wu H, Ge J
Experimental and molecular pathology 2020 Jun;114:104402
Experimental and molecular pathology 2020 Jun;114:104402
Beneficial Effects of Theta-Burst Transcranial Magnetic Stimulation on Stroke Injury via Improving Neuronal Microenvironment and Mitochondrial Integrity.
Zong X, Dong Y, Li Y, Yang L, Li Y, Yang B, Tucker L, Zhao N, Brann DW, Yan X, Hu S, Zhang Q
Translational stroke research 2020 Jun;11(3):450-467
Translational stroke research 2020 Jun;11(3):450-467
Pseudolaric acid B induces mitotic arrest and apoptosis in both imatinib-sensitive and -resistant chronic myeloid leukaemia cells.
Jiang L, Wen C, He Q, Sun Y, Wang J, Lan X, Rohondia S, Dou QP, Shi X, Liu J
European journal of pharmacology 2020 Jun 5;876:173064
European journal of pharmacology 2020 Jun 5;876:173064
lncRNA MIRF Promotes Cardiac Apoptosis through the miR-26a-Bak1 Axis.
Su X, Lv L, Li Y, Fang R, Yang R, Li C, Li T, Zhu D, Li X, Zhou Y, Shan H, Liang H
Molecular therapy. Nucleic acids 2020 Jun 5;20:841-850
Molecular therapy. Nucleic acids 2020 Jun 5;20:841-850
Paeoniflorin-6'-O-benzene sulfonate down-regulates CXCR4-Gβγ-PI3K/AKT mediated migration in fibroblast-like synoviocytes of rheumatoid arthritis by inhibiting GRK2 translocation.
Wang DD, Jiang MY, Wang W, Zhou WJ, Zhang YW, Yang M, Chen JY, Wei W
Biochemical and biophysical research communications 2020 Jun 4;526(3):805-812
Biochemical and biophysical research communications 2020 Jun 4;526(3):805-812
Deletion of the Impg2 gene causes the degeneration of rod and cone cells in mice.
Xu H, Qu C, Gan L, Sun K, Tan J, Liu X, Jiang Z, Tian W, Liu W, Zhang S, Yang Y, Jiang L, Zhu X, Zhang L
Human molecular genetics 2020 Jun 27;29(10):1624-1634
Human molecular genetics 2020 Jun 27;29(10):1624-1634
The RBP1-CKAP4 axis activates oncogenic autophagy and promotes cancer progression in oral squamous cell carcinoma.
Gao L, Wang Q, Ren W, Zheng J, Li S, Dou Z, Kong X, Liang X, Zhi K
Cell death & disease 2020 Jun 25;11(6):488
Cell death & disease 2020 Jun 25;11(6):488
A Gold(I) Complex Containing an Oleanolic Acid Derivative as a Potential Anti-Ovarian-Cancer Agent by Inhibiting TrxR and Activating ROS-Mediated ERS.
Bian M, Sun Y, Liu Y, Xu Z, Fan R, Liu Z, Liu W
Chemistry (Weinheim an der Bergstrasse, Germany) 2020 Jun 2;26(31):7092-7108
Chemistry (Weinheim an der Bergstrasse, Germany) 2020 Jun 2;26(31):7092-7108
YBX1 mediates autophagy by targeting p110β and decreasing the sensitivity to cisplatin in NSCLC.
Cui Y, Li F, Xie Q, Zhao S, Guo T, Guo P, Hu S, Hao J, Tian C, Yu W, Li Z, Fang L, Zhao L, Chen M, Wu T, Gu C
Cell death & disease 2020 Jun 19;11(6):476
Cell death & disease 2020 Jun 19;11(6):476
Role of mitochondrial acyl-CoA dehydrogenases in the metabolism of dicarboxylic fatty acids.
Bharathi SS, Zhang Y, Gong Z, Muzumdar R, Goetzman ES
Biochemical and biophysical research communications 2020 Jun 18;527(1):162-166
Biochemical and biophysical research communications 2020 Jun 18;527(1):162-166
Drp1, a potential therapeutic target for Parkinson's disease, is involved in olfactory bulb pathological alteration in the Rotenone-induced rat model.
Zhang X, Huang W, Shao Q, Yang Y, Xu Z, Chen J, Zhang X, Ge X
Toxicology letters 2020 Jun 1;325:1-13
Toxicology letters 2020 Jun 1;325:1-13
LncRNA-H19 induces hepatic stellate cell activation via upregulating alcohol dehydrogenase III-mediated retinoic acid signals.
Wang ZM, Xia SW, Zhang T, Wang ZY, Yang X, Kai J, Cheng XD, Shao JJ, Tan SZ, Chen AP, Wang SJ, Zhang F, Zhang ZL, Zheng SZ
International immunopharmacology 2020 Jul;84:106470
International immunopharmacology 2020 Jul;84:106470
Network Pharmacology and Bioactive Equivalence Assessment Integrated Strategy Driven Q-markers Discovery for Da-Cheng-Qi Decoction to Attenuate Intestinal Obstruction.
Li D, Lv B, Wang D, Xu D, Qin S, Zhang Y, Chen J, Zhang W, Zhang Z, Xu F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Jul;72:153236
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Jul;72:153236
The up-regulation of NDRG1 by HIF counteracts the cancer-promoting effect of HIF in VHL-deficient clear cell renal cell carcinoma.
Zhang ZY, Zhang SL, Chen HL, Mao YQ, Li ZM, Kong CY, Han B, Zhang J, Chen YH, Xue W, Zhai W, Wang LS
Cell proliferation 2020 Jul;53(7):e12853
Cell proliferation 2020 Jul;53(7):e12853
Pycnogenol achieves neuroprotective effects in rats with spinal cord injury by stabilizing the mitochondrial membrane potential.
Tao L, Liu X, Da W, Tao Z, Zhu Y
Neurological research 2020 Jul;42(7):597-604
Neurological research 2020 Jul;42(7):597-604
Expression of lncRNA-HOTAIR in the serum of patients with lymph node metastasis of papillary thyroid carcinoma and its impact.
Wu L, Shi Y, Liu B, Zhao M
Oncology letters 2020 Jul;20(1):907-913
Oncology letters 2020 Jul;20(1):907-913
Leucine-rich α-2-glycoprotein-1 promotes diabetic corneal epithelial wound healing and nerve regeneration via regulation of matrix metalloproteinases.
Li W, Wang X, Cheng J, Li J, Wang Q, Zhou Q, Li H, Xue J, Zhang Y, Yang L, Xie L
Experimental eye research 2020 Jul;196:108060
Experimental eye research 2020 Jul;196:108060
Fingolimod (FTY720) improves postoperative cognitive dysfunction in mice subjected to D-galactose-induced aging.
Zhang J, Xiao B, Li CX, Wang Y
Neural regeneration research 2020 Jul;15(7):1308-1315
Neural regeneration research 2020 Jul;15(7):1308-1315
Resveratrol slows the tumourigenesis of pancreatic cancer by inhibiting NFκB activation.
Qian W, Xiao Q, Wang L, Qin T, Xiao Y, Li J, Yue Y, Zhou C, Duan W, Ma Q, Ma J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110116
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110116
The Establishment and Application Studies on Precise Lysosome pH Indicator Based on Self-Decomposable Nanoparticles.
Pang C, Song C, Li Y, Wang Q, Zhu X, Wu J, Tian Y, Fan H, Hu J, Li C, Wang B, Li X, Liu W, Fan L
Nanoscale research letters 2020 Jul 8;15(1):143
Nanoscale research letters 2020 Jul 8;15(1):143
PD-L1 promotes tumor growth and progression by activating WIP and β-catenin signaling pathways and predicts poor prognosis in lung cancer.
Yu W, Hua Y, Qiu H, Hao J, Zou K, Li Z, Hu S, Guo P, Chen M, Sui S, Xiong Y, Li F, Lu J, Guo W, Luo G, Deng W
Cell death & disease 2020 Jul 6;11(7):506
Cell death & disease 2020 Jul 6;11(7):506
Elevated expression of minichromosome maintenance 3 indicates poor outcomes and promotes G1/S cell cycle progression, proliferation, migration and invasion in colorectal cancer.
Zhou H, Xiong Y, Zhang G, Liu Z, Li L, Hou S, Zhou T
Bioscience reports 2020 Jul 31;40(7)
Bioscience reports 2020 Jul 31;40(7)
miR-5089-5p suppresses castration-resistant prostate cancer resistance to enzalutamide and metastasis via miR-5089-5p/SPINK1/ MAPK/MMP9 signaling.
Wang ZC, Li Y, Wang KL, Wang L, You BS, Zhao DF, Liu ZQ, Fang RZ, Wang JQ, Zhang W, Zhang JM, Xu WH
Aging 2020 Jul 21;12(14):14418-14433
Aging 2020 Jul 21;12(14):14418-14433
Nintedanib Reduces Neutrophil Chemotaxis via Activating GRK2 in Bleomycin-Induced Pulmonary Fibrosis.
Chen WC, Chen NJ, Chen HP, Yu WK, Su VY, Chen H, Wu HH, Yang KY
International journal of molecular sciences 2020 Jul 2;21(13)
International journal of molecular sciences 2020 Jul 2;21(13)
Myeloid cells protect intestinal epithelial barrier integrity through the angiogenin/plexin-B2 axis.
Bai R, Sun D, Chen M, Shi X, Luo L, Yao Z, Liu Y, Ge X, Gao X, Hu GF, Zhou W, Sheng J, Xu Z
The EMBO journal 2020 Jul 1;39(13):e103325
The EMBO journal 2020 Jul 1;39(13):e103325
Euscaphic acid and Tormentic acid protect vascular endothelial cells against hypoxia-induced apoptosis via PI3K/AKT or ERK 1/2 signaling pathway.
Shi C, Li Z, Wu Y, Li X, Li Y, Wei J, Li J, Zhang Y, Li L
Life sciences 2020 Jul 1;252:117666
Life sciences 2020 Jul 1;252:117666
Antitumor activity of celastrol by inhibition of proliferation, invasion, and migration in cholangiocarcinoma via PTEN/PI3K/Akt pathway.
Zhu B, Wei Y
Cancer medicine 2020 Jan;9(2):783-796
Cancer medicine 2020 Jan;9(2):783-796
PRRX1-induced epithelial-to-mesenchymal transition in salivary adenoid cystic carcinoma activates the metabolic reprogramming of free fatty acids to promote invasion and metastasis.
Jiang YP, Tang YL, Wang SS, Wu JS, Zhang M, Pang X, Wu JB, Chen Y, Tang YJ, Liang XH
Cell proliferation 2020 Jan;53(1):e12705
Cell proliferation 2020 Jan;53(1):e12705
α-Ketoglutarate Modulates Macrophage Polarization Through Regulation of PPARγ Transcription and mTORC1/p70S6K Pathway to Ameliorate ALI/ARDS.
Liu M, Chen Y, Wang S, Zhou H, Feng D, Wei J, Shi X, Wu L, Zhang P, Yang H, Lv X
Shock (Augusta, Ga.) 2020 Jan;53(1):103-113
Shock (Augusta, Ga.) 2020 Jan;53(1):103-113
miRNA‑342 suppresses renal interstitial fibrosis in diabetic nephropathy by targeting SOX6.
Jiang ZH, Tang YZ, Song HN, Yang M, Li B, Ni CL
International journal of molecular medicine 2020 Jan;45(1):45-52
International journal of molecular medicine 2020 Jan;45(1):45-52
Insulin secretion impairment induced by rosuvastatin partly though autophagy in INS-1E cells.
Qian L, Zhu K, Lin Y, An L, Huang F, Yao Y, Ren L
Cell biology international 2020 Jan;44(1):127-136
Cell biology international 2020 Jan;44(1):127-136
MiR-22 restrains proliferation of rheumatoid arthritis by targeting IL6R and may be concerned with the suppression of NF-κB pathway.
Yang QY, Yang KP, Li ZZ
The Kaohsiung journal of medical sciences 2020 Jan;36(1):20-26
The Kaohsiung journal of medical sciences 2020 Jan;36(1):20-26
Scavenger receptor A impairs interferon response to HBV infection by limiting TRAF3 ubiquitination through recruiting OTUB1.
Xie M, Yin Y, Chen L, Yin A, Liu Y, Liu Y, Dong L, Lai Q, Zhou J, Zhang L, Xu M, Chen Z, Zuo D
The FEBS journal 2020 Jan;287(2):310-324
The FEBS journal 2020 Jan;287(2):310-324
Fluoride induced mitochondrial impairment and PINK1-mediated mitophagy in Leydig cells of mice: In vivo and in vitro studies.
Liang C, Gao Y, He Y, Han Y, Manthari RK, Tikka C, Chen C, Wang J, Zhang J
Environmental pollution (Barking, Essex : 1987) 2020 Jan;256:113438
Environmental pollution (Barking, Essex : 1987) 2020 Jan;256:113438
NRSN2 promotes breast cancer metastasis by activating PI3K/AKT/mTOR and NF-κB signaling pathways.
Ren F, Zhang W, Lu S, Ren H, Guo Y
Oncology letters 2020 Jan;19(1):813-823
Oncology letters 2020 Jan;19(1):813-823
LINC00365-SCGB2A1 axis inhibits the viability of breast cancer through targeting NF-κB signaling.
Zhang L, Yan X, Yu S, Zhong X, Tian R, Xu L, Bian X, Su J
Oncology letters 2020 Jan;19(1):753-762
Oncology letters 2020 Jan;19(1):753-762
MicroRNA-150 functions as a tumor suppressor and sensitizes osteosarcoma to doxorubicin-induced apoptosis by targeting RUNX2.
Ling Z, Fan G, Yao D, Zhao J, Zhou Y, Feng J, Zhou G, Chen Y
Experimental and therapeutic medicine 2020 Jan;19(1):481-488
Experimental and therapeutic medicine 2020 Jan;19(1):481-488
Matrine suppresses breast cancer metastasis by targeting ITGB1 and inhibiting epithelial-to-mesenchymal transition.
Ren L, Mo W, Wang L, Wang X
Experimental and therapeutic medicine 2020 Jan;19(1):367-374
Experimental and therapeutic medicine 2020 Jan;19(1):367-374
Effect of stromal cell-derived factor-1/CXCR4 axis in neural stem cell transplantation for Parkinson's disease.
Xu JT, Qian Y, Wang W, Chen XX, Li Y, Li Y, Yang ZY, Song XB, Lu D, Deng XL
Neural regeneration research 2020 Jan;15(1):112-119
Neural regeneration research 2020 Jan;15(1):112-119
Perilla oil regulates intestinal microbiota and alleviates insulin resistance through the PI3K/AKT signaling pathway in type-2 diabetic KKAy mice.
Wang J, He Y, Yu D, Jin L, Gong X, Zhang B
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Jan;135:110965
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Jan;135:110965
Involvement of proliferative and apoptotic factors in the development of hindgut in rat fetuses with ethylenethiourea-induced anorectal malformations.
Long C, Xiao Y, Li S, Tang X, Yuan Z, Bai Y
Acta histochemica 2020 Jan;122(1):151466
Acta histochemica 2020 Jan;122(1):151466
Naturally-derived diterpenoid sphaeropsidin C as an activator of Nrf2/ARE pathway and its potential capability of relieving intracellular oxidative stress in human lung epithelial cells.
Li GH, Li AL, Chen XM, Zhang LY, Wang T, Wang XN, Shen T
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109669
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109669
Human umbilical cord blood mononuclear cells protect against renal tubulointerstitial fibrosis in cisplatin-treated rats.
Li XW, Feng LX, Zhu XJ, Liu Q, Wang HS, Wu X, Yan P, Duan XJ, Xiao YQ, Cheng W, Peng JC, Zhao F, Deng YH, Duan SB
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109310
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109310
Deoxycholic Acid Upregulates the Reprogramming Factors KFL4 and OCT4 Through the IL-6/STAT3 Pathway in Esophageal Adenocarcinoma Cells.
Chen M, Ye A, Wei J, Wang R, Poon K
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820945302
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820945302
Odor-mediated contextual learning induced memory consolidation and hippocampus development in neonate rat.
Cao J, Xu J, Chen S, Fan F, Chen M, Liu F, Li G
Neuroreport 2020 Jan 8;31(1):64-68
Neuroreport 2020 Jan 8;31(1):64-68
Aspirin enhances the sensitivity of colon cancer cells to cisplatin by abrogating the binding of NF-κB to the COX-2 promoter.
Jiang W, Yan Y, Chen M, Luo G, Hao J, Pan J, Hu S, Guo P, Li W, Wang R, Zuo Y, Sun Y, Sui S, Yu W, Pan Z, Zou K, Zheng Z, Deng W, Wu X, Guo W
Aging 2020 Jan 6;12(1):611-627
Aging 2020 Jan 6;12(1):611-627
Protective effects of Salidroside on spermatogenesis in streptozotocin induced type-1 diabetic male mice by inhibiting oxidative stress mediated blood-testis barrier damage.
Jiang YP, Ye RJ, Yang JM, Liu N, Zhang WJ, Ma L, Sun T, Niu JG, Zheng P, Yu JQ
Chemico-biological interactions 2020 Jan 5;315:108869
Chemico-biological interactions 2020 Jan 5;315:108869
Suppression of Notch Signaling Stimulates Progesterone Synthesis by Enhancing the Expression of NR5A2 and NR2F2 in Porcine Granulosa Cells.
Guo R, Chen F, Shi Z
Genes 2020 Jan 22;11(2)
Genes 2020 Jan 22;11(2)
Romo1 is involved in the immune response of glioblastoma by regulating the function of macrophages.
Sun G, Cao Y, Qian C, Wan Z, Zhu J, Guo J, Shi L
Aging 2020 Jan 16;12(2):1114-1127
Aging 2020 Jan 16;12(2):1114-1127
Angiotensin II-Induced vascular remodeling and hypertension involves cathepsin L/V- MEK/ERK mediated mechanism.
Lu Y, Sun X, Peng L, Jiang W, Li W, Yuan H, Cai J
International journal of cardiology 2020 Jan 1;298:98-106
International journal of cardiology 2020 Jan 1;298:98-106
The testis-specific gene 1700102P08Rik is essential for male fertility.
Wu XL, Yun DM, Gao S, Liang AJ, Duan ZZ, Wang HS, Wang GS, Sun F
Molecular reproduction and development 2020 Feb;87(2):231-240
Molecular reproduction and development 2020 Feb;87(2):231-240
Asiaticoside nitric oxide gel accelerates diabetic cutaneous ulcers healing by activating Wnt/β-catenin signaling pathway.
Nie X, Zhang H, Shi X, Zhao J, Chen Y, Wu F, Yang J, Li X
International immunopharmacology 2020 Feb;79:106109
International immunopharmacology 2020 Feb;79:106109
FLI1 promotes protein translation via the transcriptional regulation of MKNK1 expression.
Wang C, Song J, Liu W, Yao Y, Kapranov P, Sample KM, Gajendran B, Zacksenhaus E, Hao X, Ben-David Y
International journal of oncology 2020 Feb;56(2):430-438
International journal of oncology 2020 Feb;56(2):430-438
Screening for reproductive biomarkers in Bactrian camel via iTRAQ analysis of proteomes.
Wang Q, Zhang Q, Gan Z, Li H, Yang Y, Zhang Y, Zhao X
Reproduction in domestic animals = Zuchthygiene 2020 Feb;55(2):189-199
Reproduction in domestic animals = Zuchthygiene 2020 Feb;55(2):189-199
Resveratrol Downregulates STAT3 Expression and Astrocyte Activation in Primary Astrocyte Cultures of Rat.
Wu M, Wang L, Li F, Hu R, Ma J, Zhang K, Cheng X
Neurochemical research 2020 Feb;45(2):455-464
Neurochemical research 2020 Feb;45(2):455-464
Dendrobium Alkaloids Promote Neural Function After Cerebral Ischemia-Reperfusion Injury Through Inhibiting Pyroptosis Induced Neuronal Death in both In Vivo and In Vitro Models.
Liu D, Dong Z, Xiang F, Liu H, Wang Y, Wang Q, Rao J
Neurochemical research 2020 Feb;45(2):437-454
Neurochemical research 2020 Feb;45(2):437-454
Study of the protective effect on damaged intestinal epithelial cells of rat multilineage-differentiating stress-enduring (Muse) cells.
Sun D, Yang L, Cao H, Shen ZY, Song HL
Cell biology international 2020 Feb;44(2):549-559
Cell biology international 2020 Feb;44(2):549-559
Programmed cell death protein 1 promotes hepatitis B virus transmission through the regulation of ERK1/2-mediated trophoblasts differentiation.
Yang J, Liu J, Sheng M, Zhang X, Liu M
Archives of gynecology and obstetrics 2020 Feb;301(2):551-558
Archives of gynecology and obstetrics 2020 Feb;301(2):551-558
Anti-insulin resistance effects of salidroside through mitochondrial quality control.
You B, Dun Y, Zhang W, Jiang L, Li H, Xie M, Liu Y, Liu S
The Journal of endocrinology 2020 Feb;244(2):383-393
The Journal of endocrinology 2020 Feb;244(2):383-393
Inhibition of PFKFB3 suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss.
Wang J, Guan H, Liu H, Lei Z, Kang H, Guo Q, Dong Y, Liu H, Sun Y, Fang Z, Li F
Journal of cellular and molecular medicine 2020 Feb;24(3):2294-2307
Journal of cellular and molecular medicine 2020 Feb;24(3):2294-2307
Post-production modifications of murine mesenchymal stem cell (mMSC) derived extracellular vesicles (EVs) and impact on their cellular interaction.
Le Saux S, Aarrass H, Lai-Kee-Him J, Bron P, Armengaud J, Miotello G, Bertrand-Michel J, Dubois E, George S, Faklaris O, Devoisselle JM, Legrand P, Chopineau J, Morille M
Biomaterials 2020 Feb;231:119675
Biomaterials 2020 Feb;231:119675
CMIP promotes Herceptin resistance of HER2 positive gastric cancer cells.
Xiang R, Han X, Ding K, Wu Z
Pathology, research and practice 2020 Feb;216(2):152776
Pathology, research and practice 2020 Feb;216(2):152776
Inhibition of calcineurin/NFATc4 signaling attenuates ventilator‑induced lung injury.
Li M, Fang XZ, Liu XT, Zheng YF, Xie YB, Ma XD, Xia Y, Shao DH
Molecular medicine reports 2020 Feb;21(2):607-614
Molecular medicine reports 2020 Feb;21(2):607-614
Effects of dexmedetomidine on oxidative stress and inflammatory response in lungs during mechanical ventilation in COPD rats.
Li P, Han J, Zhang D, Cao S, Su C
Experimental and therapeutic medicine 2020 Feb;19(2):1219-1224
Experimental and therapeutic medicine 2020 Feb;19(2):1219-1224
Elevated levels of arachidonic acid metabolites in follicular fluid of PCOS patients.
Li S, Qi J, Tao Y, Zhu Q, Huang R, Liao Y, Yue J, Liu W, Zhao H, Yin H, Sun Y
Reproduction (Cambridge, England) 2020 Feb;159(2):159-169
Reproduction (Cambridge, England) 2020 Feb;159(2):159-169
Isorhamnetin attenuates Streptococcus suis virulence by inhibiting the inflammatory response.
Li G, Wang G, Wang S, Sun M, Wen Z
Antonie van Leeuwenhoek 2020 Feb;113(2):303-310
Antonie van Leeuwenhoek 2020 Feb;113(2):303-310
Targeting the miR-122/PKM2 autophagy axis relieves arsenic stress.
Wang Y, Zhao H, Guo M, Fei D, Zhang L, Xing M
Journal of hazardous materials 2020 Feb 5;383:121217
Journal of hazardous materials 2020 Feb 5;383:121217
A20 targets PFKL and glycolysis to inhibit the progression of hepatocellular carcinoma.
Feng Y, Zhang Y, Cai Y, Liu R, Lu M, Li T, Fu Y, Guo M, Huang H, Ou Y, Chen Y
Cell death & disease 2020 Feb 3;11(2):89
Cell death & disease 2020 Feb 3;11(2):89
Colorectal cancer-derived exosomal miR-106b-3p promotes metastasis by down-regulating DLC-1 expression.
Liu H, Liu Y, Sun P, Leng K, Xu Y, Mei L, Han P, Zhang B, Yao K, Li C, Bai J, Cui B
Clinical science (London, England : 1979) 2020 Feb 28;134(4):419-434
Clinical science (London, England : 1979) 2020 Feb 28;134(4):419-434
Minicircle DNA vector expressing interferon-lambda-3 inhibits hepatitis B virus replication and expression in hepatocyte-derived cell line.
Guo X, Chen D, Cai Q, Huang Z, Xu W, Peng L, Chen P
BMC molecular and cell biology 2020 Feb 18;21(1):6
BMC molecular and cell biology 2020 Feb 18;21(1):6
A tropomyosin-like Meretrix meretrix Linnaeus polypeptide inhibits the proliferation and metastasis of glioma cells via microtubule polymerization and FAK/Akt/MMPs signaling.
Fan Z, Xu Q, Wang C, Lin X, Zhang Q, Wu N
International journal of biological macromolecules 2020 Feb 15;145:154-164
International journal of biological macromolecules 2020 Feb 15;145:154-164
Transactivation of miR-202-5p by Steroidogenic Factor 1 (SF1) Induces Apoptosis in Goat Granulosa Cells by Targeting TGFβR2.
Ding Q, Jin M, Wang Y, Liu J, Kalds P, Wang Y, Yang Y, Wang X, Chen Y
Cells 2020 Feb 14;9(2)
Cells 2020 Feb 14;9(2)
GPAT3 deficiency alleviates insulin resistance and hepatic steatosis in a mouse model of severe congenital generalized lipodystrophy.
Gao M, Liu L, Wang X, Mak HY, Liu G, Yang H
Human molecular genetics 2020 Feb 1;29(3):432-443
Human molecular genetics 2020 Feb 1;29(3):432-443
Protection of diabetes-induced kidney injury by phosphocreatine via the regulation of ERK/Nrf2/HO-1 signaling pathway.
Shopit A, Niu M, Wang H, Tang Z, Li X, Tesfaldet T, Ai J, Ahmad N, Al-Azab M, Tang Z
Life sciences 2020 Feb 1;242:117248
Life sciences 2020 Feb 1;242:117248
Fine-tuning of the respiratory complexes stability and supercomplexes assembly in cells defective of complex III.
Tropeano CV, Aleo SJ, Zanna C, Roberti M, Scandiffio L, Loguercio Polosa P, Fiori J, Porru E, Roda A, Carelli V, Steimle S, Daldal F, Rugolo M, Ghelli A
Biochimica et biophysica acta. Bioenergetics 2020 Feb 1;1861(2):148133
Biochimica et biophysica acta. Bioenergetics 2020 Feb 1;1861(2):148133
Honokiol inhibits the growth of SKBR3 cells.
Shi H, Wang Y, Yao M, Zhang D, Fang W, Zhou T, Gan D, Yue S, Qian H, Chen T
Translational cancer research 2020 Dec;9(12):7596-7604
Translational cancer research 2020 Dec;9(12):7596-7604
Geniposide in Gardenia jasminoides var. radicans Makino modulates blood pressure via inhibiting WNK pathway mediated by the estrogen receptors.
Fu Y, Yuan PP, Cao YG, Ke YY, Zhang Q, Hou Y, Zhang YL, Feng WS, Zheng XK
The Journal of pharmacy and pharmacology 2020 Dec;72(12):1956-1969
The Journal of pharmacy and pharmacology 2020 Dec;72(12):1956-1969
MicroRNA-217 ameliorates inflammatory damage of endothelial cells induced by oxidized LDL by targeting EGR1.
Yang X, Li D, Qi YZ, Chen W, Yang CH, Jiang YH
Molecular and cellular biochemistry 2020 Dec;475(1-2):41-51
Molecular and cellular biochemistry 2020 Dec;475(1-2):41-51
Alprostadil attenuates LPS-induced cardiomyocyte injury by inhibiting the Wnt5a/JNK/NF-κB pathway.
Yu T, Dong D, Guan J, Sun J, Guo M, Wang Q
Herz 2020 Dec;45(Suppl 1):130-138
Herz 2020 Dec;45(Suppl 1):130-138
Exogenous CGRP Regulates Apoptosis and Autophagy to Alleviate Traumatic Brain Injury Through Akt/mTOR Signalling Pathway.
Tian J, Yang L, Wang P, Yang L, Fan Z
Neurochemical research 2020 Dec;45(12):2926-2938
Neurochemical research 2020 Dec;45(12):2926-2938
Acylglycerol kinase promotes the stemness of nasopharyngeal carcinoma cells by promoting β-catenin translocation to the nucleus through activating PI3K/Akt pathway.
Zhao Q, Sun P, Qin S, Liu J
Environmental toxicology 2020 Dec;35(12):1299-1307
Environmental toxicology 2020 Dec;35(12):1299-1307
Myeloid-derived suppressor cells promote epithelial ovarian cancer cell stemness by inducing the CSF2/p-STAT3 signalling pathway.
Li X, Wang J, Wu W, Gao H, Liu N, Zhan G, Li L, Han L, Guo X
The FEBS journal 2020 Dec;287(23):5218-5235
The FEBS journal 2020 Dec;287(23):5218-5235
Co-delivery of paclitaxel and anti-VEGF siRNA by tripeptide lipid nanoparticle to enhance the anti-tumor activity for lung cancer therapy.
Zhang C, Zhao Y, Zhang E, Jiang M, Zhi D, Chen H, Cui S, Zhen Y, Cui J, Zhang S
Drug delivery 2020 Dec;27(1):1397-1411
Drug delivery 2020 Dec;27(1):1397-1411
Poldip2 mediates blood-brain barrier disruption and cerebral edema by inducing AQP4 polarity loss in mouse bacterial meningitis model.
Gao M, Lu W, Shu Y, Yang Z, Sun S, Xu J, Gan S, Zhu S, Qiu G, Zhuo F, Xu S, Wang Y, Chen J, Wu X, Huang J
CNS neuroscience & therapeutics 2020 Dec;26(12):1288-1302
CNS neuroscience & therapeutics 2020 Dec;26(12):1288-1302
Inhibition of miRNA-29a regulates intestinal barrier function in diarrhea-predominant irritable bowel syndrome by upregulating ZO-1 and CLDN1.
Zhu H, Xiao X, Shi Y, Wu Y, Huang Y, Li D, Xiong F, He G, Chai Y, Tang H
Experimental and therapeutic medicine 2020 Dec;20(6):155
Experimental and therapeutic medicine 2020 Dec;20(6):155
Baicalin reversal of DNA hypermethylation-associated Klotho suppression ameliorates renal injury in type 1 diabetic mouse model.
Zhang XT, Wang G, Ye LF, Pu Y, Li RT, Liang J, Wang L, Lee KKH, Yang X
Cell cycle (Georgetown, Tex.) 2020 Dec;19(23):3329-3347
Cell cycle (Georgetown, Tex.) 2020 Dec;19(23):3329-3347
Functional Food XingJiuTang Attenuates Alcohol-Induced Liver Injury by Regulating SIRT1/Nrf-2 Signaling Pathway.
Hao J, Ding Y, Shi W, Zhang C, Li R
Chemistry & biodiversity 2020 Dec;17(12):e2000619
Chemistry & biodiversity 2020 Dec;17(12):e2000619
TLR4 inhibition ameliorates mesencephalic substantia nigra injury in neonatal rats exposed to lipopolysaccharide via regulation of neuro-immunity.
He W, Jiang M, Mao P, Yan F
Brain research bulletin 2020 Dec;165:90-96
Brain research bulletin 2020 Dec;165:90-96
Saikosaponin-d impedes hippocampal neurogenesis and causes cognitive deficits by inhibiting the survival of neural stem/progenitor cells via neurotrophin receptor signaling in mice.
Qin T, Yuan Z, Yu J, Fu X, Deng X, Fu Q, Ma Z, Ma S
Clinical and translational medicine 2020 Dec;10(8):e243
Clinical and translational medicine 2020 Dec;10(8):e243
Transforming growth factor beta type 1 (TGF-β) and hypoxia-inducible factor 1 (HIF-1) transcription complex as master regulators of the immunosuppressive protein galectin-9 expression in human cancer and embryonic cells.
Selnø ATH, Schlichtner S, Yasinska IM, Sakhnevych SS, Fiedler W, Wellbrock J, Klenova E, Pavlova L, Gibbs BF, Degen M, Schnyder I, Aliu N, Berger SM, Fasler-Kan E, Sumbayev VV
Aging 2020 Dec 8;12(23):23478-23496
Aging 2020 Dec 8;12(23):23478-23496
MicroRNA-410-3p Binds to TLR2 and Alleviates Myocardial Mitochondrial Dysfunction and Chemokine Production in LPS-Induced Sepsis.
Zuo T, Tang Q, Zhang X, Shang F
Molecular therapy. Nucleic acids 2020 Dec 4;22:273-284
Molecular therapy. Nucleic acids 2020 Dec 4;22:273-284
Curcumin protects rat hippocampal neurons against pseudorabies virus by regulating the BDNF/TrkB pathway.
Yang B, Luo G, Zhang C, Feng L, Luo X, Gan L
Scientific reports 2020 Dec 17;10(1):22204
Scientific reports 2020 Dec 17;10(1):22204
Multi-walled carbon nanotubes decrease neuronal NO synthase in 3D brain organoids.
Jiang Y, Gong H, Jiang S, She C, Cao Y
The Science of the total environment 2020 Dec 15;748:141384
The Science of the total environment 2020 Dec 15;748:141384
Decreased Expression of the Host Long-Noncoding RNA-GM Facilitates Viral Escape by Inhibiting the Kinase activity TBK1 via S-glutathionylation.
Wang Y, Wang P, Zhang Y, Xu J, Li Z, Li Z, Zhou Z, Liu L, Cao X
Immunity 2020 Dec 15;53(6):1168-1181.e7
Immunity 2020 Dec 15;53(6):1168-1181.e7
Initiation of PI3K/AKT pathway by IGF-1 decreases spinal cord injury-induced endothelial apoptosis and microvascular damage.
Li H, Kong R, Wan B, Yang L, Zhang S, Cao X, Chen H
Life sciences 2020 Dec 15;263:118572
Life sciences 2020 Dec 15;263:118572
Discovery of potent small molecule PROTACs targeting mutant EGFR.
Zhao HY, Yang XY, Lei H, Xi XX, Lu SM, Zhang JJ, Xin M, Zhang SQ
European journal of medicinal chemistry 2020 Dec 15;208:112781
European journal of medicinal chemistry 2020 Dec 15;208:112781
An autoregulatory feedback loop of miR-21/VMP1 is responsible for the abnormal expression of miR-21 in colorectal cancer cells.
Wang C, Peng R, Zeng M, Zhang Z, Liu S, Jiang D, Lu Y, Zou F
Cell death & disease 2020 Dec 14;11(12):1067
Cell death & disease 2020 Dec 14;11(12):1067
Indoxyl sulfate promotes osteogenic differentiation of vascular smooth muscle cells by miR-155-5p-dependent downregulation of matrix Gla protein via ROS/NF-κB signaling.
He X, Wang Z, Wei L, Cheng X, Chen L, Gao F, Jiang H
Experimental cell research 2020 Dec 1;397(1):112301
Experimental cell research 2020 Dec 1;397(1):112301
Berberine alleviates cisplatin-induced acute kidney injury by regulating mitophagy via PINK 1/Parkin pathway.
Qi J, Xue Q, Kuang L, Xie L, Luo R, Nie X
Translational andrology and urology 2020 Aug;9(4):1712-1724
Translational andrology and urology 2020 Aug;9(4):1712-1724
Minocycline prevents the depressive-like behavior through inhibiting the release of HMGB1 from microglia and neurons.
Wang B, Huang X, Pan X, Zhang T, Hou C, Su WJ, Liu LL, Li JM, Wang YX
Brain, behavior, and immunity 2020 Aug;88:132-143
Brain, behavior, and immunity 2020 Aug;88:132-143
Melatonin Ameliorates Renal Fibrosis Through the Inhibition of NF-κB and TGF-β1/Smad3 Pathways in db/db Diabetic Mice.
Fan Z, Qi X, Yang W, Xia L, Wu Y
Archives of medical research 2020 Aug;51(6):524-534
Archives of medical research 2020 Aug;51(6):524-534
LncRNA XIST promotes chemoresistance of breast cancer cells to doxorubicin by sponging miR-200c-3p to upregulate ANLN.
Zhang M, Wang F, Xiang Z, Huang T, Zhou WB
Clinical and experimental pharmacology & physiology 2020 Aug;47(8):1464-1472
Clinical and experimental pharmacology & physiology 2020 Aug;47(8):1464-1472
Role of the Nucleotide-Binding Domain-Like Receptor Protein 3 Inflammasome in the Endothelial Dysfunction of Early Sepsis.
Luo M, Meng J, Yan J, Shang F, Zhang T, Lv D, Li C, Yang X, Luo S
Inflammation 2020 Aug;43(4):1561-1571
Inflammation 2020 Aug;43(4):1561-1571
Integrin-α9 and Its Corresponding Ligands Play Regulatory Roles in Chronic Periodontitis.
Xu S, Jiang C, Liu H, Zhang H, Liao H, Wang X, Yao S, Ma L, Guo Y, Cao Z
Inflammation 2020 Aug;43(4):1488-1497
Inflammation 2020 Aug;43(4):1488-1497
The metabolic changes in the hippocampus of an atherosclerotic rat model and the regulation of aerobic training.
Liu B, Li J, Lin X, Hu J, Lou S
Metabolic brain disease 2020 Aug;35(6):1017-1034
Metabolic brain disease 2020 Aug;35(6):1017-1034
USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylation.
Rusilowicz-Jones EV, Jardine J, Kallinos A, Pinto-Fernandez A, Guenther F, Giurrandino M, Barone FG, McCarron K, Burke CJ, Murad A, Martinez A, Marcassa E, Gersch M, Buckmelter AJ, Kayser-Bricker KJ, Lamoliatte F, Gajbhiye A, Davis S, Scott HC, Murphy E, England K, Mortiboys H, Komander D, Trost M, Kessler BM, Ioannidis S, Ahlijanian MK, Urbé S, Clague MJ
Life science alliance 2020 Aug;3(8)
Life science alliance 2020 Aug;3(8)
PRDM16 orchestrates angiogenesis via neural differentiation in the developing brain.
Su L, Lei X, Ma H, Feng C, Jiang J, Jiao J
Cell death and differentiation 2020 Aug;27(8):2313-2329
Cell death and differentiation 2020 Aug;27(8):2313-2329
MiR-34a affects G2 arrest in prostate cancer PC3 cells via Wnt pathway and inhibits cell growth and migration.
Dong B, Xu GC, Liu ST, Liu T, Geng B
European review for medical and pharmacological sciences 2020 Aug;24(16):8349-8358
European review for medical and pharmacological sciences 2020 Aug;24(16):8349-8358
Vitamin D3 protects articular cartilage by inhibiting the Wnt/β-catenin signaling pathway.
Yang T, Sun W, Duan YH, Sun YB, Ren YM, Hou WY, Tian MQ
Experimental and therapeutic medicine 2020 Aug;20(2):1775-1781
Experimental and therapeutic medicine 2020 Aug;20(2):1775-1781
Graphene oxide size-dependently altered lipid profiles in THP-1 macrophages.
Luo Y, Peng J, Huang C, Cao Y
Ecotoxicology and environmental safety 2020 Aug;199:110714
Ecotoxicology and environmental safety 2020 Aug;199:110714
Identification of EMT-related high-risk stage II colorectal cancer and characterisation of metastasis-related genes.
Wang K, Song K, Ma Z, Yao Y, Liu C, Yang J, Xiao H, Zhang J, Zhang Y, Zhao W
British journal of cancer 2020 Aug;123(3):410-417
British journal of cancer 2020 Aug;123(3):410-417
Activation of the Hedgehog Pathway Promotes Recovery of Neurological Function After Traumatic Brain Injury by Protecting the Neurovascular Unit.
Wu J, He J, Tian X, Zhong J, Li H, Sun X
Translational stroke research 2020 Aug;11(4):720-733
Translational stroke research 2020 Aug;11(4):720-733
A mutation found in esophageal cancer alters integrin β4 mRNA splicing.
Kelly GT, Faraj R, Dai Z, Cress AE, Wang T
Biochemical and biophysical research communications 2020 Aug 27;529(3):726-732
Biochemical and biophysical research communications 2020 Aug 27;529(3):726-732
BCCIPβ facilitates p53 ubiquitination via binding with E6 protein in high-risk HPV positive head and neck squamous cell carcinoma.
Wang F, Wang J, Wang J, Zhang L, Fu H, Li J, Tian T, Zuo J, Lv W, Ma X
Biochemical and biophysical research communications 2020 Aug 27;529(3):685-691
Biochemical and biophysical research communications 2020 Aug 27;529(3):685-691
FB-15 inhibits MGC-803 cells growth by regulating energy metabolism.
Deng X, Pi Y, Li Z, Xiong R, Liu J, Zhao J, Xie Z, Lei X, Tang G
Chemico-biological interactions 2020 Aug 25;327:109186
Chemico-biological interactions 2020 Aug 25;327:109186
BVES downregulation in non-syndromic tetralogy of fallot is associated with ventricular outflow tract stenosis.
Shi Y, Li Y, Wang Y, Zhu P, Chen Y, Wang H, Yue S, Xia X, Chen J, Jiang Z, Zhou C, Cai W, Yuan H, Wu Y, Wan Y, Li X, Zhu X, Zhou Z, Dai G, Li F, Mo X, Ye X, Fan X, Zhuang J, Wu X, Yuan W
Scientific reports 2020 Aug 25;10(1):14167
Scientific reports 2020 Aug 25;10(1):14167
ZEB1-Mediated Transcriptional Upregulation of circWWC3 Promotes Breast Cancer Progression through Activating Ras Signaling Pathway.
Meng L, Liu S, Liu F, Sang M, Ju Y, Fan X, Gu L, Li Z, Geng C, Sang M
Molecular therapy. Nucleic acids 2020 Aug 19;22:124-137
Molecular therapy. Nucleic acids 2020 Aug 19;22:124-137
Computational repositioning of dimethyl fumarate for treating alcoholic liver disease.
Zhang Y, Zhao S, Fu Y, Yan L, Feng Y, Chen Y, Wu Y, Deng Y, Zhang G, Chen Z, Chen Y, Liu T
Cell death & disease 2020 Aug 18;11(8):641
Cell death & disease 2020 Aug 18;11(8):641
Silychristin A activates Nrf2-HO-1/SOD2 pathway to reduce apoptosis and improve GLP-1 production through upregulation of estrogen receptor α in GLUTag cells.
Wang J, Zhang X, Zhang L, Yan T, Wu B, Xu F, Jia Y
European journal of pharmacology 2020 Aug 15;881:173236
European journal of pharmacology 2020 Aug 15;881:173236
Metformin ameliorates cardiac conduction delay by regulating microRNA-1 in mice.
Lv L, Zheng N, Zhang L, Li R, Li Y, Yang R, Li C, Fang R, Shabanova A, Li X, Liu Y, Liang H, Zhou Y, Shan H
European journal of pharmacology 2020 Aug 15;881:173131
European journal of pharmacology 2020 Aug 15;881:173131
Antagomirs targeting miR-142-5p attenuate pilocarpine-induced status epilepticus in mice.
Zhang H, Lian Y, Xie N, Cheng X, Chen C, Xu H, Zheng Y
Experimental cell research 2020 Aug 15;393(2):112089
Experimental cell research 2020 Aug 15;393(2):112089
Sulforaphane enhances the cisplatin sensitivity through regulating DNA repair and accumulation of intracellular cisplatin in ovarian cancer cells.
Gong TT, Liu XD, Zhan ZP, Wu QJ
Experimental cell research 2020 Aug 15;393(2):112061
Experimental cell research 2020 Aug 15;393(2):112061
HIF-1α-upregulated lncRNA-H19 regulates lipid droplet metabolism through the AMPKα pathway in hepatic stellate cells.
Wang Z, Yang X, Kai J, Wang F, Wang Z, Shao J, Tan S, Chen A, Zhang F, Wang S, Zhang Z, Zheng S
Life sciences 2020 Aug 15;255:117818
Life sciences 2020 Aug 15;255:117818
Progesterone promotes endothelial nitric oxide synthase expression through enhancing nuclear progesterone receptor-SP-1 formation.
You Y, Tan W, Guo Y, Luo M, Shang FF, Xia Y, Luo S
American journal of physiology. Heart and circulatory physiology 2020 Aug 1;319(2):H341-H348
American journal of physiology. Heart and circulatory physiology 2020 Aug 1;319(2):H341-H348
A multi-scale systems pharmacology approach uncovers the anti-cancer molecular mechanism of Ixabepilone.
Cao DS, Jiang SL, Guan YD, Chen XS, Zhang LX, Zhang Y, Chen AF, Yang JM, Cheng Y
European journal of medicinal chemistry 2020 Aug 1;199:112421
European journal of medicinal chemistry 2020 Aug 1;199:112421
Pyrazinamide alleviates rifampin-induced steatohepatitis in mice by regulating the activities of cholesterol-activated 7α-hydroxylase and lipoprotein lipase.
Tan W, Zhao K, Xiang J, Zhou X, Cao F, Song W, Liu Q, Zhang X, Li X, Tan Z
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2020 Aug 1;151:105402
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2020 Aug 1;151:105402
Exogenous hydrogen sulfide inhibits human melanoma cell development via suppression of the PI3K/AKT/ mTOR pathway.
Xiao Q, Ying J, Qiao Z, Yang Y, Dai X, Xu Z, Zhang C, Xiang L
Journal of dermatological science 2020 Apr;98(1):26-34
Journal of dermatological science 2020 Apr;98(1):26-34
Responses of intestinal morphology and function in offspring to heat stress in primiparous sows during late gestation.
Guo H, He J, Yang X, Zheng W, Yao W
Journal of thermal biology 2020 Apr;89:102539
Journal of thermal biology 2020 Apr;89:102539
Hydrogen sulfide inhibits cigarette smoke-induced inflammation and injury in alveolar epithelial cells by suppressing PHD2/HIF-1α/MAPK signaling pathway.
Guan R, Wang J, Li D, Li Z, Liu H, Ding M, Cai Z, Liang X, Yang Q, Long Z, Chen L, Liu W, Sun D, Yao H, Lu W
International immunopharmacology 2020 Apr;81:105979
International immunopharmacology 2020 Apr;81:105979
Lycopene attenuates body weight gain through induction of browning via regulation of peroxisome proliferator-activated receptor γ in high-fat diet-induced obese mice.
Zhu R, Wei J, Liu H, Liu C, Wang L, Chen B, Li L, Jia Q, Tian Y, Li R, Zhao D, Mo F, Li Y, Gao S, Wang XD, Zhang D
The Journal of nutritional biochemistry 2020 Apr;78:108335
The Journal of nutritional biochemistry 2020 Apr;78:108335
Identification of novel variants in the FZD4 gene associated with familial exudative vitreoretinopathy in Chinese families.
Xu H, Zhang S, Huang L, Zhao P, Zhang X, Yang Z, Zhang L
Clinical & experimental ophthalmology 2020 Apr;48(3):356-365
Clinical & experimental ophthalmology 2020 Apr;48(3):356-365
High- and low-virulent bovine Pasteurella multocida induced differential NLRP3 inflammasome activation and subsequent IL-1β secretion.
Fang R, Lei G, Jiang J, Du H, Liu Y, Lei Z, Ye C, Li N, Peng Y
Veterinary microbiology 2020 Apr;243:108646
Veterinary microbiology 2020 Apr;243:108646
Stromal fibroblast-derived MFAP5 promotes the invasion and migration of breast cancer cells via Notch1/slug signaling.
Chen Z, Yan X, Li K, Ling Y, Kang H
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2020 Apr;22(4):522-531
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2020 Apr;22(4):522-531
Decreased basal and stimulated salivary parameters by histopathological lesions and secretory dysfunction of parotid and submandibular glands in rats with type 2 diabetes.
Chen SY, Wang Y, Zhang CL, Yang ZM
Experimental and therapeutic medicine 2020 Apr;19(4):2707-2719
Experimental and therapeutic medicine 2020 Apr;19(4):2707-2719
Novel nortriterpenoids with new skeletons and limonoids from the fruits of Evodia rutaecarpa and their bioactivities.
Shi YS, Xia HM, Wu CH, Li CB, Duan CC, Che C, Zhang XJ, Li HT, Zhang Y, Zhang XF
Fitoterapia 2020 Apr;142:104503
Fitoterapia 2020 Apr;142:104503
SMAD3/SP1 complex-mediated constitutive active loop between lncRNA PCAT7 and TGF-β signaling promotes prostate cancer bone metastasis.
Lang C, Dai Y, Wu Z, Yang Q, He S, Zhang X, Guo W, Lai Y, Du H, Wang H, Ren D, Peng X
Molecular oncology 2020 Apr;14(4):808-828
Molecular oncology 2020 Apr;14(4):808-828
Paradoxical Pro-inflammatory Responses by Human Macrophages to an Amoebae Host-Adapted Legionella Effector.
Price C, Jones S, Mihelcic M, Santic M, Abu Kwaik Y
Cell host & microbe 2020 Apr 8;27(4):571-584.e7
Cell host & microbe 2020 Apr 8;27(4):571-584.e7
Calcium-sensing receptor promotes tumor proliferation and migration in human intrahepatic cholangiocarcinoma by targeting ERK signaling pathway.
Fang Y, Liu L, Liu S, Hu L, Cai W, Wan X, Liu D, He Y, Zhu Z
European journal of pharmacology 2020 Apr 5;872:172915
European journal of pharmacology 2020 Apr 5;872:172915
Ablation of glutaredoxin 1 promotes pulmonary angiogenesis and alveolar formation in hyperoxia-injured lungs by modifying HIF-1α stability and inhibiting the NF-κB pathway.
Liu X, Li K, Zhang F, Zhang Y, Deng C, Guo C
Biochemical and biophysical research communications 2020 Apr 30;525(2):528-535
Biochemical and biophysical research communications 2020 Apr 30;525(2):528-535
An inducible intestinal epithelial cell-specific NHE3 knockout mouse model mimicking congenital sodium diarrhea.
Xue J, Thomas L, Tahmasbi M, Valdez A, Dominguez Rieg JA, Fenton RA, Rieg T
Clinical science (London, England : 1979) 2020 Apr 30;134(8):941-953
Clinical science (London, England : 1979) 2020 Apr 30;134(8):941-953
RNA-seq analysis of potential lncRNAs for age-related hearing loss in a mouse model.
Zhao T, Liu X, Sun Z, Zhang J, Zhang X, Wang C, Geng R, Zheng T, Li B, Zheng QY
Aging 2020 Apr 26;12(8):7491-7510
Aging 2020 Apr 26;12(8):7491-7510
CACNA1H downregulation induces skeletal muscle atrophy involving endoplasmic reticulum stress activation and autophagy flux blockade.
Li S, Hao M, Li B, Chen M, Chen J, Tang J, Hong S, Min J, Hu M, Hong L
Cell death & disease 2020 Apr 24;11(4):279
Cell death & disease 2020 Apr 24;11(4):279
MicroRNA-183 regulates lipopolysaccharide-induced oxidative stress of hippocampal neurons by targeting the fibronectin 1 gene.
Xie Q, Feng L, Zhang C, Gan L
Neuroscience letters 2020 Apr 23;725:134902
Neuroscience letters 2020 Apr 23;725:134902
Asperosaponin VI Injection Enhances Orthodontic Tooth Movement in Rats.
Ma D, Wang X, Ren X, Bu J, Zheng D, Zhang J
Medical science monitor : international medical journal of experimental and clinical research 2020 Apr 23;26:e922372
Medical science monitor : international medical journal of experimental and clinical research 2020 Apr 23;26:e922372
Posterior Neocortex-Specific Regulation of Neuronal Migration by CEP85L Identifies Maternal Centriole-Dependent Activation of CDK5.
Kodani A, Kenny C, Lai A, Gonzalez DM, Stronge E, Sejourne GM, Isacco L, Partlow JN, O'Donnell A, McWalter K, Byrne AB, Barkovich AJ, Yang E, Hill RS, Gawlinski P, Wiszniewski W, Cohen JS, Fatemi SA, Baranano KW, Sahin M, Vossler DG, Yuskaitis CJ, Walsh CA
Neuron 2020 Apr 22;106(2):246-255.e6
Neuron 2020 Apr 22;106(2):246-255.e6
Effect of KIF22 on promoting proliferation and migration of gastric cancer cells via MAPK-ERK pathways.
Yu ZY, Jiang XY, Zhao RR, Qin JJ, Luo CJ, Ren YX, Ren W, Ma ZJ, Jiao ZY
Chinese medical journal 2020 Apr 20;133(8):919-928
Chinese medical journal 2020 Apr 20;133(8):919-928
CCL5 derived from tumor-associated macrophages promotes prostate cancer stem cells and metastasis via activating β-catenin/STAT3 signaling.
Huang R, Wang S, Wang N, Zheng Y, Zhou J, Yang B, Wang X, Zhang J, Guo L, Wang S, Chen Z, Wang Z, Xiang S
Cell death & disease 2020 Apr 16;11(4):234
Cell death & disease 2020 Apr 16;11(4):234
Histone Deacetylation 10 Alleviates Inflammation After Intracerebral Hemorrhage via the PTPN22/NLRP3 Pathway in Rats.
Wang L, Zheng S, Zhang L, Xiao H, Gan H, Chen H, Zhai X, Liang P, Zhao J, Li Y
Neuroscience 2020 Apr 15;432:247-259
Neuroscience 2020 Apr 15;432:247-259
All-trans-retinal induces autophagic cell death via oxidative stress and the endoplasmic reticulum stress pathway in human retinal pigment epithelial cells.
Zhang L, Zhou Y, Xia Q, Chen Y, Li J
Toxicology letters 2020 Apr 1;322:77-86
Toxicology letters 2020 Apr 1;322:77-86
Targeting β2 subunit of Na(+)/K(+)-ATPase induces glioblastoma cell apoptosis through elevation of intracellular Ca(2).
Li S, Dai Z, Yang D, Li W, Dai H, Sun B, Liu X, Xie X, Xu R, Zhao X
American journal of cancer research 2019;9(6):1293-1308
American journal of cancer research 2019;9(6):1293-1308
p66Shc Contributes to Liver Fibrosis through the Regulation of Mitochondrial Reactive Oxygen Species.
Zhao Y, Wang Z, Feng D, Zhao H, Lin M, Hu Y, Zhang N, Lv L, Gao Z, Zhai X, Tian X, Yao J
Theranostics 2019;9(5):1510-1522
Theranostics 2019;9(5):1510-1522
LncRNA-MTA2TR functions as a promoter in pancreatic cancer via driving deacetylation-dependent accumulation of HIF-1α.
Zeng Z, Xu FY, Zheng H, Cheng P, Chen QY, Ye Z, Zhong JX, Deng SJ, Liu ML, Huang K, Li Q, Li W, Hu YH, Wang F, Wang CY, Zhao G
Theranostics 2019;9(18):5298-5314
Theranostics 2019;9(18):5298-5314
Targeting mitochondrial dynamics by regulating Mfn2 for therapeutic intervention in diabetic cardiomyopathy.
Hu L, Ding M, Tang D, Gao E, Li C, Wang K, Qi B, Qiu J, Zhao H, Chang P, Fu F, Li Y
Theranostics 2019;9(13):3687-3706
Theranostics 2019;9(13):3687-3706
STAT3 Contributes To Oncolytic Newcastle Disease Virus-Induced Immunogenic Cell Death in Melanoma Cells.
Shao X, Wang X, Guo X, Jiang K, Ye T, Chen J, Fang J, Gu L, Wang S, Zhang G, Meng S, Xu Q
Frontiers in oncology 2019;9:436
Frontiers in oncology 2019;9:436
Antitumor Effects of Berberine on Gliomas via Inactivation of Caspase-1-Mediated IL-1β and IL-18 Release.
Tong L, Xie C, Wei Y, Qu Y, Liang H, Zhang Y, Xu T, Qian X, Qiu H, Deng H
Frontiers in oncology 2019;9:364
Frontiers in oncology 2019;9:364
PNS-R1 inhibits Dex-induced bronchial epithelial cells apoptosis in asthma through mitochondrial apoptotic pathway.
Zou W, Niu C, Fu Z, Gong C
Cell & bioscience 2019;9:18
Cell & bioscience 2019;9:18
MiR-24-3p Inhibits the Progression of Pancreatic Ductal Adenocarcinoma Through LAMB3 Downregulation.
Huang W, Gu J, Tao T, Zhang J, Wang H, Fan Y
Frontiers in oncology 2019;9:1499
Frontiers in oncology 2019;9:1499
The Binding of PD-L1 and Akt Facilitates Glioma Cell Invasion Upon Starvation via Akt/Autophagy/F-Actin Signaling.
Chen RQ, Xu XH, Liu F, Li CY, Li YJ, Li XR, Jiang GY, Hu F, Liu D, Pan F, Qiu XY, Chen XQ
Frontiers in oncology 2019;9:1347
Frontiers in oncology 2019;9:1347
Critical role of Tim-3 mediated autophagy in chronic stress induced immunosuppression.
Qin A, Zhong T, Zou H, Wan X, Yao B, Zheng X, Yin D
Cell & bioscience 2019;9:13
Cell & bioscience 2019;9:13
MTHFD1L-Mediated Redox Homeostasis Promotes Tumor Progression in Tongue Squamous Cell Carcinoma.
Li H, Fu X, Yao F, Tian T, Wang C, Yang A
Frontiers in oncology 2019;9:1278
Frontiers in oncology 2019;9:1278
Chrysanthemum extract attenuates hepatotoxicity via inhibiting oxidative stress in vivo and in vitro.
Tian Z, Jia H, Jin Y, Wang M, Kou J, Wang C, Rong X, Xie X, Han G, Pang X
Food & nutrition research 2019;63
Food & nutrition research 2019;63
Mild hypothermia improves neurological outcome in mice after cardiopulmonary resuscitation through Silent Information Regulator 1-actviated autophagy.
Wei H, Yin M, Lu Y, Yang Y, Li B, Liao XX, Dai G, Jing X, Xiong Y, Hu C
Cell death discovery 2019;5:129
Cell death discovery 2019;5:129
Inhibition of Mitochondrial Complex I Aggravates Folic Acid-Induced Acute Kidney Injury.
Zhang W, Yang Y, Gao H, Zhang Y, Jia Z, Huang S
Kidney & blood pressure research 2019;44(5):1002-1013
Kidney & blood pressure research 2019;44(5):1002-1013
Targeting autophagy enhances heat stress-induced apoptosis via the ATP-AMPK-mTOR axis for hepatocellular carcinoma.
Jiang J, Chen S, Li K, Zhang C, Tan Y, Deng Q, Chai Y, Wang X, Chen G, Feng K, Zhang L, Xie CM, Ma K
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2019;36(1):499-510
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2019;36(1):499-510
SOCS3 control the activity of NF-κB induced by HSP70 via degradation of MyD88-adapter-like protein (Mal) in IPEC-J2 cells.
Yong YH, Wang P, Jia RM, Gooneratne R, Robert Wang HC, Liao M, Ju XH
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2019;36(1):151-159
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2019;36(1):151-159
LncRNA ZFAS1 promotes proliferation and migration and inhibits apoptosis in nasopharyngeal carcinoma via the PI3K/AKT pathway in vitro.
Wang X, Jin Q, Wang X, Chen W, Cai Z
Cancer biomarkers : section A of Disease markers 2019;26(2):171-182
Cancer biomarkers : section A of Disease markers 2019;26(2):171-182
Long non-coding RNA MAGI2-AS3 inhibits breast cancer cell migration and invasion via sponging microRNA-374a.
Du S, Hu W, Zhao Y, Zhou H, Wen W, Xu M, Zhao P, Liu K
Cancer biomarkers : section A of Disease markers 2019;24(3):269-277
Cancer biomarkers : section A of Disease markers 2019;24(3):269-277
UHRF1 Promotes Proliferation of Human Adipose-Derived Stem Cells and Suppresses Adipogenesis via Inhibiting Peroxisome Proliferator-Activated Receptor γ.
Chen K, Guo Z, Luo Y, Yuan J, Mo Z
BioMed research international 2019;2019:9456847
BioMed research international 2019;2019:9456847
Mechanisms of Aerobic Exercise Upregulating the Expression of Hippocampal Synaptic Plasticity-Associated Proteins in Diabetic Rats.
Li J, Liu Y, Liu B, Li F, Hu J, Wang Q, Li M, Lou S
Neural plasticity 2019;2019:7920540
Neural plasticity 2019;2019:7920540
Spica Prunellae Extract Enhances Fluorouracil Sensitivity of 5-Fluorouracil-Resistant Human Colon Carcinoma HCT-8/5-FU Cells via TOP2α and miR-494.
Fang Y, Yang C, Zhang L, Wei L, Lin J, Zhao J, Peng J
BioMed research international 2019;2019:5953619
BioMed research international 2019;2019:5953619
Hepatitis B Virus X Protein-Induced RORγ Expression to Promote the Migration and Proliferation of Hepatocellular Carcinoma.
Huang Y, Liang H, He C, Peng F
BioMed research international 2019;2019:5407126
BioMed research international 2019;2019:5407126
Primary Cilia Blockage Promotes the Malignant Behaviors of Hepatocellular Carcinoma via Induction of Autophagy.
Liu L, Sheng JQ, Wang MR, Gan Y, Wu XL, Liao JZ, Tian DA, He XX, Li PY
BioMed research international 2019;2019:5202750
BioMed research international 2019;2019:5202750
Carnosine Protects Mouse Podocytes from High Glucose Induced Apoptosis through PI3K/AKT and Nrf2 Pathways.
Zhao K, Li Y, Wang Z, Han N, Wang Y
BioMed research international 2019;2019:4348973
BioMed research international 2019;2019:4348973
Analysis of Toll-Like Receptors in Human Milk: Detection of Membrane-Bound and Soluble Forms.
Cattaneo C, Caramaschi A, Uga E, Braghin M, Cosi G, Peila C, Strozzi MC, Sabatini M, Gazzolo D, Manfredi M, Cavaletto M
Journal of immunology research 2019;2019:4078671
Journal of immunology research 2019;2019:4078671
Alleviation of Hepatic Ischemia Reperfusion Injury by Oleanolic Acid Pretreating via Reducing HMGB1 Release and Inhibiting Apoptosis and Autophagy.
Wang W, Wu L, Li J, Ji J, Chen K, Yu Q, Li S, Feng J, Liu T, Zhang J, Chen J, Zhou Y, Mao Y, Wang F, Dai W, Fan X, Guo C, Wu J
Mediators of inflammation 2019;2019:3240713
Mediators of inflammation 2019;2019:3240713
Atorvastatin Inhibits Breast Cancer Cells by Downregulating PTEN/AKT Pathway via Promoting Ras Homolog Family Member B (RhoB).
Ma Q, Gao Y, Xu P, Li K, Xu X, Gao J, Qi Y, Xu J, Yang Y, Song W, He X, Liu S, Yuan X, Yin W, He Y, Pan W, Wei L, Zhang J
BioMed research international 2019;2019:3235021
BioMed research international 2019;2019:3235021
Nrf2/Keap1/ARE Signaling Mediated an Antioxidative Protection of Human Placental Mesenchymal Stem Cells of Fetal Origin in Alveolar Epithelial Cells.
Yan X, Fu X, Jia Y, Ma X, Tao J, Yang T, Ma H, Liang X, Liu X, Yang J, Wei J
Oxidative medicine and cellular longevity 2019;2019:2654910
Oxidative medicine and cellular longevity 2019;2019:2654910
Jiawei Foshou San Induces Apoptosis in Ectopic Endometrium Based on Systems Pharmacology, Molecular Docking, and Experimental Evidence.
Wei J, Zhao B, Zhang C, Shen B, Zhang Y, Li C, Chen Y
Evidence-based complementary and alternative medicine : eCAM 2019;2019:2360367
Evidence-based complementary and alternative medicine : eCAM 2019;2019:2360367
Jiedu Sangen Decoction Inhibits the Invasion and Metastasis of Colorectal Cancer Cells by Regulating EMT through the Hippo Signaling Pathway.
Yuan L, Zhou M, Wasan HS, Zhang K, Li Z, Guo K, Shen F, Shen M, Ruan S
Evidence-based complementary and alternative medicine : eCAM 2019;2019:1431726
Evidence-based complementary and alternative medicine : eCAM 2019;2019:1431726
RAD51 is a potential marker for prognosis and regulates cell proliferation in pancreatic cancer.
Zhang X, Ma N, Yao W, Li S, Ren Z
Cancer cell international 2019;19:356
Cancer cell international 2019;19:356
Casticin inhibits nasopharyngeal carcinoma growth by targeting phosphoinositide 3-kinase.
Liu J, Yang J, Hou Y, Zhu Z, He J, Zhao H, Ye X, Li D, Wu Z, Huang Z, Hao B, Yao K
Cancer cell international 2019;19:348
Cancer cell international 2019;19:348
SIRT6/HIF-1α axis promotes papillary thyroid cancer progression by inducing epithelial-mesenchymal transition.
Yang Z, Yu W, Huang R, Ye M, Min Z
Cancer cell international 2019;19:17
Cancer cell international 2019;19:17
TGF-β1 Induces Epithelial-Mesenchymal Transition of Chronic Sinusitis with Nasal Polyps through MicroRNA-21.
Li X, Li C, Zhu G, Yuan W, Xiao ZA
International archives of allergy and immunology 2019;179(4):304-319
International archives of allergy and immunology 2019;179(4):304-319
Anti-apoptotic effect of the Shh signaling pathway in cigarette smoke extract induced MLE 12 apoptosis.
Li J, Zong D, Chen Y, Chen P
Tobacco induced diseases 2019;17:49
Tobacco induced diseases 2019;17:49
P11 Loss-of-Function is Associated with Decreased Cell Proliferation and Neurobehavioral Disorders in Mice.
Liu G, Wang Y, Zheng W, Cheng H, Zhou R
International journal of biological sciences 2019;15(7):1383-1395
International journal of biological sciences 2019;15(7):1383-1395
Glycolytic Enzyme PKM2 Mediates Autophagic Activation to Promote Cell Survival in NPM1-Mutated Leukemia.
Wang L, Yang L, Yang Z, Tang Y, Tao Y, Zhan Q, Lei L, Jing Y, Jiang X, Jin H, Zou Q, Xian J, Zhang L
International journal of biological sciences 2019;15(4):882-894
International journal of biological sciences 2019;15(4):882-894
LncRNA SLCO4A1-AS1 predicts poor prognosis and promotes proliferation and metastasis via the EGFR/MAPK pathway in colorectal cancer.
Tang R, Chen J, Tang M, Liao Z, Zhou L, Jiang J, Hu Y, Liao Q, Xiong W, Tang Y, Nie S
International journal of biological sciences 2019;15(13):2885-2896
International journal of biological sciences 2019;15(13):2885-2896
LncRNA expression profile during autophagy and Malat1 function in macrophages.
Ma Z, Zhang J, Xu X, Qu Y, Dong H, Dang J, Huo Z, Xu G
PloS one 2019;14(8):e0221104
PloS one 2019;14(8):e0221104
NAMPT overexpression alleviates alcohol-induced hepatic steatosis in mice.
Xiong X, Yu J, Fan R, Zhang C, Xu L, Sun X, Huang Y, Wang Q, Ruan HB, Qian X
PloS one 2019;14(2):e0212523
PloS one 2019;14(2):e0212523
Porous Se@SiO(2) nanocomposite promotes migration and osteogenic differentiation of rat bone marrow mesenchymal stem cell to accelerate bone fracture healing in a rat model.
Li C, Wang Q, Gu X, Kang Y, Zhang Y, Hu Y, Li T, Jin H, Deng G, Wang Q
International journal of nanomedicine 2019;14:3845-3860
International journal of nanomedicine 2019;14:3845-3860
Inhibition of COX2/PGD2-Related Autophagy Is Involved in the Mechanism of Brain Injury in T2DM Rat.
Yang Y, Chen Q, Zhao Q, Luo Y, Xu Y, Du W, Wang H, Li H, Yang L, Hu C, Zhang J, Li Y, Xia H, Chen Z, Ma J, Tian X, Yang J
Frontiers in cellular neuroscience 2019;13:68
Frontiers in cellular neuroscience 2019;13:68
Bone Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote Recovery Following Spinal Cord Injury via Improvement of the Integrity of the Blood-Spinal Cord Barrier.
Lu Y, Zhou Y, Zhang R, Wen L, Wu K, Li Y, Yao Y, Duan R, Jia Y
Frontiers in neuroscience 2019;13:209
Frontiers in neuroscience 2019;13:209
CITED1 contributes to the progression of papillary thyroid carcinoma via the Wnt/β-catenin signaling pathway.
Wang Y, Huang H, Hu F, Li J, Zhang L, Pang H
OncoTargets and therapy 2019;12:6769-6777
OncoTargets and therapy 2019;12:6769-6777
GPX2 suppression of H(2)O(2) stress regulates cervical cancer metastasis and apoptosis via activation of the β-catenin-WNT pathway.
Wang Y, Cao P, Alshwmi M, Jiang N, Xiao Z, Jiang F, Gu J, Wang X, Sun X, Li S
OncoTargets and therapy 2019;12:6639-6651
OncoTargets and therapy 2019;12:6639-6651
SIRT6 promotes the Warburg effect of papillary thyroid cancer cell BCPAP through reactive oxygen species.
Yu W, Yang Z, Huang R, Min Z, Ye M
OncoTargets and therapy 2019;12:2861-2868
OncoTargets and therapy 2019;12:2861-2868
Prognostic implications and oncogenic roles of MYBL2 protein expression in esophageal squamous-cell carcinoma.
Qin H, Li Y, Zhang H, Wang F, He H, Bai X, Li S
OncoTargets and therapy 2019;12:1917-1927
OncoTargets and therapy 2019;12:1917-1927
DHT deteriorates the progression of monocrotaline-induced pulmonary arterial hypertension: effects of endogenous and exogenous androgen.
Wen J, Wang J, Tang X, Deng S, Dai J, Li X, Cai W
American journal of translational research 2019;11(9):5752-5763
American journal of translational research 2019;11(9):5752-5763
miR-23a-5p inhibits cell proliferation and invasion in pancreatic ductal adenocarcinoma by suppressing ECM1 expression.
Huang W, Huang Y, Gu J, Zhang J, Yang J, Liu S, Xie C, Fan Y, Wang H
American journal of translational research 2019;11(5):2983-2994
American journal of translational research 2019;11(5):2983-2994
Catalpol improves axonal outgrowth and reinnervation of injured sciatic nerve by activating Akt/mTOR pathway and regulating BDNF and PTEN expression.
Zhu H, Wang Y, Yang X, Wan G, Qiu Y, Ye X, Gao Y, Wan D
American journal of translational research 2019;11(3):1311-1326
American journal of translational research 2019;11(3):1311-1326
The IRE1α-XBP1 pathway function in hypoxia-induced pulmonary vascular remodeling, is upregulated by quercetin, inhibits apoptosis and partially reverses the effect of quercetin in PASMCs.
Cao X, He Y, Li X, Xu Y, Liu X
American journal of translational research 2019;11(2):641-654
American journal of translational research 2019;11(2):641-654
Rutin suppresses FNDC1 expression in bone marrow mesenchymal stem cells to inhibit postmenopausal osteoporosis.
Xiao Y, Wei R, Yuan Z, Lan X, Kuang J, Hu D, Song Y, Luo J
American journal of translational research 2019;11(10):6680-6690
American journal of translational research 2019;11(10):6680-6690
The lncRNA HOXA11-AS regulates Rab3D expression by sponging miR-125a-5p promoting metastasis of osteosarcoma.
Cao K, Fang Y, Wang H, Jiang Z, Guo L, Hu Y
Cancer management and research 2019;11:4505-4518
Cancer management and research 2019;11:4505-4518
High expression of SMARCE1 predicts poor prognosis and promotes cell growth and metastasis in gastric cancer.
Liu H, Zhao YR, Chen B, Ge Z, Huang JS
Cancer management and research 2019;11:3493-3509
Cancer management and research 2019;11:3493-3509
Catalpol Exerts a Neuroprotective Effect in the MPTP Mouse Model of Parkinson's Disease.
Wang LY, Yu X, Li XX, Zhao YN, Wang CY, Wang ZY, He ZY
Frontiers in aging neuroscience 2019;11:316
Frontiers in aging neuroscience 2019;11:316
MARCH5 overexpression contributes to tumor growth and metastasis and associates with poor survival in breast cancer.
Tang H, Peng S, Dong Y, Yang X, Yang P, Yang L, Yang B, Bao G
Cancer management and research 2019;11:201-215
Cancer management and research 2019;11:201-215
AAV-Mig-6 Increase the Efficacy of TAE in VX2 Rabbit Model, Is Associated With JNK Mediated Autophagy.
Li Z, Tian Y, Qu L, Mao J, Zhong H
Journal of Cancer 2019;10(4):1060-1069
Journal of Cancer 2019;10(4):1060-1069
Up-regulation of EMT-related gene VCAN by NPM1 mutant-driven TGF-β/cPML signalling promotes leukemia cell invasion.
Yang L, Wang L, Yang Z, Jin H, Zou Q, Zhan Q, Tang Y, Tao Y, Lei L, Jing Y, Jiang X, Zhang L
Journal of Cancer 2019;10(26):6570-6583
Journal of Cancer 2019;10(26):6570-6583
SIRT5 Promotes Hepatocellular Carcinoma Progression by Regulating Mitochondrial Apoptosis.
Zhang R, Wang C, Tian Y, Yao Y, Mao J, Wang H, Li Z, Xu Y, Ye M, Wang L
Journal of Cancer 2019;10(16):3871-3882
Journal of Cancer 2019;10(16):3871-3882
Involvement of Actin-Regulating Factor Cofilin in the Inclusion Body Formation and RNA Synthesis of Human Parainfluenza Virus Type 3 via Interaction With the Nucleoprotein.
Li Y, Zhang C, Lu N, Deng X, Zang G, Zhang S, Tang H, Zhang G
Frontiers in microbiology 2019;10:95
Frontiers in microbiology 2019;10:95
Naringenin Produces Neuroprotection Against LPS-Induced Dopamine Neurotoxicity via the Inhibition of Microglial NLRP3 Inflammasome Activation.
Chen C, Wei YZ, He XM, Li DD, Wang GQ, Li JJ, Zhang F
Frontiers in immunology 2019;10:936
Frontiers in immunology 2019;10:936
miR-181b-5p May Regulate Muscle Growth in Tilapia by Targeting Myostatin b.
Zhao Z, Yu X, Jia J, Yang G, Sun C, Li W
Frontiers in endocrinology 2019;10:812
Frontiers in endocrinology 2019;10:812
TLR4/NF-κB Signaling Induces GSDMD-Related Pyroptosis in Tubular Cells in Diabetic Kidney Disease.
Wang Y, Zhu X, Yuan S, Wen S, Liu X, Wang C, Qu Z, Li J, Liu H, Sun L, Liu F
Frontiers in endocrinology 2019;10:603
Frontiers in endocrinology 2019;10:603
The Wnt/β-Catenin/LEF1 Pathway Promotes Cell Proliferation at Least in Part Through Direct Upregulation of miR-17-92 Cluster.
Mu F, Huang J, Xing T, Jing Y, Cui T, Guo Y, Yan X, Li H, Wang N
Frontiers in genetics 2019;10:525
Frontiers in genetics 2019;10:525
Combined melatonin and poricoic acid A inhibits renal fibrosis through modulating the interaction of Smad3 and β-catenin pathway in AKI-to-CKD continuum.
Chen DQ, Cao G, Zhao H, Chen L, Yang T, Wang M, Vaziri ND, Guo Y, Zhao YY
Therapeutic advances in chronic disease 2019;10:2040622319869116
Therapeutic advances in chronic disease 2019;10:2040622319869116
Protective Effects of 18β-Glycyrrhetinic Acid on Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats.
Zhang M, Chang Z, Zhao F, Zhang P, Hao YJ, Yan L, Liu N, Wang JL, Bo L, Ma P, Zhou W, Ma X, Xu QB, Zhou R
Frontiers in pharmacology 2019;10:13
Frontiers in pharmacology 2019;10:13
Downregulation of Wnt3 Suppresses Colorectal Cancer Development Through Inhibiting Cell Proliferation and Migration.
Nie X, Xia F, Liu Y, Zhou Y, Ye W, Hean P, Meng J, Liu H, Liu L, Wen J, Ren X, Chen WD, Wang YD
Frontiers in pharmacology 2019;10:1110
Frontiers in pharmacology 2019;10:1110
The Therapeutic Effects of Treadmill Exercise on Osteoarthritis in Rats by Inhibiting the HDAC3/NF-KappaB Pathway in vivo and in vitro.
Zhang H, Ji L, Yang Y, Wei Y, Zhang X, Gang Y, Lu J, Bai L
Frontiers in physiology 2019;10:1060
Frontiers in physiology 2019;10:1060
Protective mechanism of Taxifolin for chlorpyrifos neurotoxicity in BV2 cells.
Zhang C, Zhan J, Zhao M, Dai H, Deng Y, Zhou W, Zhao L
Neurotoxicology 2019 Sep;74:74-80
Neurotoxicology 2019 Sep;74:74-80
Time-dependent C5a and C5aR expression in dental pulp cells following stimulation with LTA and LPS.
Liu M, Mu H, Peng W, Zhao L, Hu W, Jiang Z, Gao L, Cao X, Li N, Han J
International journal of molecular medicine 2019 Sep;44(3):823-834
International journal of molecular medicine 2019 Sep;44(3):823-834
Fluorene-9-bisphenol inhibits epithelial-mesenchymal transition of human endometrial cancer Ishikawa cells by repressing TGF-β signaling pathway.
Wang L, Zhuang T, Li F, Wei W
Environmental science and pollution research international 2019 Sep;26(26):27407-27413
Environmental science and pollution research international 2019 Sep;26(26):27407-27413
Hydrogen inhalation protects hypoxic-ischemic brain damage by attenuating inflammation and apoptosis in neonatal rats.
Wu G, Chen Z, Wang P, Zhao M, Fujino M, Zhang C, Zhou W, Hirano SI, Li XK, Zhao L
Experimental biology and medicine (Maywood, N.J.) 2019 Sep;244(12):1017-1027
Experimental biology and medicine (Maywood, N.J.) 2019 Sep;244(12):1017-1027
Dexamethasone interferes with osteoblasts formation during osteogenesis through altering IGF-1-mediated angiogenesis.
Xu S, Guo R, Li PZ, Li K, Yan Y, Chen J, Wang G, Brand-Saberi B, Yang X, Cheng X
Journal of cellular physiology 2019 Sep;234(9):15167-15181
Journal of cellular physiology 2019 Sep;234(9):15167-15181
Resveratrol inhibits the invasion and metastasis of colon cancer through reversal of epithelial‑ mesenchymal transition via the AKT/GSK‑3β/Snail signaling pathway.
Yuan L, Zhou M, Huang D, Wasan HS, Zhang K, Sun L, Huang H, Ma S, Shen M, Ruan S
Molecular medicine reports 2019 Sep;20(3):2783-2795
Molecular medicine reports 2019 Sep;20(3):2783-2795
TAK242 suppresses the TLR4 signaling pathway and ameliorates DCD liver IRI in rats.
Zhong X, Xiao Q, Liu Z, Wang W, Lai CH, Yang W, Yue P, Ye Q, Xiao J
Molecular medicine reports 2019 Sep;20(3):2101-2110
Molecular medicine reports 2019 Sep;20(3):2101-2110
Mechanism Underlying the Protective Effect of Selenium on NO-Induced Oxidative Damage in Bovine Mammary Epithelial Cells.
Guo Y, Guo X, Yan S, Zhang B, Shi B
Biological trace element research 2019 Sep;191(1):104-114
Biological trace element research 2019 Sep;191(1):104-114
Association between CIRP expression and hypoxic-ischemic brain injury in neonatal rats.
Chen L, Tian Q, Wang W
Experimental and therapeutic medicine 2019 Sep;18(3):1515-1520
Experimental and therapeutic medicine 2019 Sep;18(3):1515-1520
REG4 is an indicator for KRAS mutant lung adenocarcinoma with TTF-1 low expression.
Sun S, Hu Z, Huang S, Ye X, Wang J, Chang J, Wu X, Wang Q, Zhang L, Hu X, Yu H
Journal of cancer research and clinical oncology 2019 Sep;145(9):2273-2283
Journal of cancer research and clinical oncology 2019 Sep;145(9):2273-2283
Novel diterpenoid-type activators of the Keap1/Nrf2/ARE signaling pathway and their regulation of redox homeostasis.
Li AL, Shen T, Wang T, Zhou MX, Wang B, Song JT, Zhang PL, Wang XL, Ren DM, Lou HX, Wang XN
Free radical biology & medicine 2019 Sep;141:21-33
Free radical biology & medicine 2019 Sep;141:21-33
Multi-walled carbon nanotubes (MWCNTs) promoted lipid accumulation in THP-1 macrophages through modulation of endoplasmic reticulum (ER) stress.
Long J, Ma W, Yu Z, Liu H, Cao Y
Nanotoxicology 2019 Sep;13(7):938-951
Nanotoxicology 2019 Sep;13(7):938-951
Targeting Exosomal EBV-LMP1 Transfer and miR-203 Expression via the NF-κB Pathway: The Therapeutic Role of Aspirin in NPC.
Zuo L, Xie Y, Tang J, Xin S, Liu L, Zhang S, Yan Q, Zhu F, Lu J
Molecular therapy. Nucleic acids 2019 Sep 6;17:175-184
Molecular therapy. Nucleic acids 2019 Sep 6;17:175-184
Enhancing the retrograde axonal transport by curcumin promotes autophagic flux in N2a/APP695swe cells.
Liang J, Zhou F, Xiong X, Zhang X, Li S, Li X, Gao M, Li Y
Aging 2019 Sep 6;11(17):7036-7050
Aging 2019 Sep 6;11(17):7036-7050
ROS/KRAS/AMPK Signaling Contributes to Gemcitabine-Induced Stem-like Cell Properties in Pancreatic Cancer.
Zhao H, Wu S, Li H, Duan Q, Zhang Z, Shen Q, Wang C, Yin T
Molecular therapy oncolytics 2019 Sep 27;14:299-312
Molecular therapy oncolytics 2019 Sep 27;14:299-312
Establishment of an Experimental Intracerebral Haemorrhage Model for Mass Effect Research using a Thermo-sensitive Hydrogel.
Gong Y, Gong Y, Hou Z, Guo T, Deng J, Hao S, Wang B
Scientific reports 2019 Sep 25;9(1):13838
Scientific reports 2019 Sep 25;9(1):13838
Protective effects of 18β-glycyrrhetinic acid on pulmonary arterial hypertension via regulation of Rho A/Rho kinsase pathway.
Zhang M, Chang Z, Zhang P, Jing Z, Yan L, Feng J, Hu Z, Xu Q, Zhou W, Ma P, Hao Y, Zhou R
Chemico-biological interactions 2019 Sep 25;311:108749
Chemico-biological interactions 2019 Sep 25;311:108749
OPA1 overexpression ameliorates mitochondrial cristae remodeling, mitochondrial dysfunction, and neuronal apoptosis in prion diseases.
Wu W, Zhao D, Shah SZA, Zhang X, Lai M, Yang D, Wu X, Guan Z, Li J, Zhao H, Li W, Gao H, Zhou X, Qiao J, Yang L
Cell death & disease 2019 Sep 24;10(10):710
Cell death & disease 2019 Sep 24;10(10):710
Structural Characterization and Antioxidant Activity of Polysaccharides from Athyrium multidentatum (Doll.) Ching in d-Galactose-Induced Aging Mice via PI3K/AKT Pathway.
Jing L, Jiang JR, Liu DM, Sheng JW, Zhang WF, Li ZJ, Wei LY
Molecules (Basel, Switzerland) 2019 Sep 16;24(18)
Molecules (Basel, Switzerland) 2019 Sep 16;24(18)
Long Noncoding RNA FAM225A Promotes Nasopharyngeal Carcinoma Tumorigenesis and Metastasis by Acting as ceRNA to Sponge miR-590-3p/miR-1275 and Upregulate ITGB3.
Zheng ZQ, Li ZX, Zhou GQ, Lin L, Zhang LL, Lv JW, Huang XD, Liu RQ, Chen F, He XJ, Kou J, Zhang J, Wen X, Li YQ, Ma J, Liu N, Sun Y
Cancer research 2019 Sep 15;79(18):4612-4626
Cancer research 2019 Sep 15;79(18):4612-4626
Age-Associated Dopaminergic Neuron Loss and Midbrain Glia Cell Phenotypic Polarization.
Wang G, Zhou Y, Wang Y, Li D, Liu J, Zhang F
Neuroscience 2019 Sep 1;415:89-96
Neuroscience 2019 Sep 1;415:89-96
Antinociceptive effect of isoorientin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
Zhang G, Liu N, Zhu C, Ma L, Yang J, Du J, Zhang W, Sun T, Niu J, Yu J
International immunopharmacology 2019 Oct;75:105753
International immunopharmacology 2019 Oct;75:105753
Macrophage migration inhibitory factor promotes the invasion and metastasis of oral squamous cell carcinoma through matrix metalloprotein-2/9.
Wang SS, Zheng M, Pang X, Zhang M, Yu XH, Wu JB, Gao XL, Wu JS, Yang X, Tang YJ, Tang YL, Liang XH
Molecular carcinogenesis 2019 Oct;58(10):1809-1821
Molecular carcinogenesis 2019 Oct;58(10):1809-1821
Bromodomain inhibitor jq1 induces cell cycle arrest and apoptosis of glioma stem cells through the VEGF/PI3K/AKT signaling pathway.
Wen N, Guo B, Zheng H, Xu L, Liang H, Wang Q, Wang D, Chen X, Zhang S, Li Y, Zhang L
International journal of oncology 2019 Oct;55(4):879-895
International journal of oncology 2019 Oct;55(4):879-895
Paip1 Indicated Poor Prognosis in Cervical Cancer and Promoted Cervical Carcinogenesis.
Li N, Piao J, Wang X, Kim KY, Bae JY, Ren X, Lin Z
Cancer research and treatment 2019 Oct;51(4):1653-1665
Cancer research and treatment 2019 Oct;51(4):1653-1665
Babao Dan induces gastric cancer cell apoptosis via regulating MAPK and NF-κB signaling pathways.
Shang H, Cao Z, Zhao J, Guan J, Liu J, Peng J, Chen Y, Joseph Sferra T, Sankararaman S, Lin J
The Journal of international medical research 2019 Oct;47(10):5106-5119
The Journal of international medical research 2019 Oct;47(10):5106-5119
Downregulation of nicotinamide N-methyltransferase inhibits migration and epithelial-mesenchymal transition of esophageal squamous cell carcinoma via Wnt/β-catenin pathway.
Cui Y, Zhang L, Wang W, Ma S, Liu H, Zang X, Zhang Y, Guan F
Molecular and cellular biochemistry 2019 Oct;460(1-2):93-103
Molecular and cellular biochemistry 2019 Oct;460(1-2):93-103
Apatinib inhibits glycolysis by suppressing the VEGFR2/AKT1/SOX5/GLUT4 signaling pathway in ovarian cancer cells.
Chen L, Cheng X, Tu W, Qi Z, Li H, Liu F, Yang Y, Zhang Z, Wang Z
Cellular oncology (Dordrecht, Netherlands) 2019 Oct;42(5):679-690
Cellular oncology (Dordrecht, Netherlands) 2019 Oct;42(5):679-690
Propofol attenuates TNF-α-induced MMP-9 expression in human cerebral microvascular endothelial cells by inhibiting Ca(2+)/CAMK II/ERK/NF-κB signaling pathway.
Ding XW, Sun X, Shen XF, Lu Y, Wang JQ, Sun ZR, Miao CH, Chen JW
Acta pharmacologica Sinica 2019 Oct;40(10):1303-1313
Acta pharmacologica Sinica 2019 Oct;40(10):1303-1313
A novel long noncoding RNA PGC1β-OT1 regulates adipocyte and osteoblast differentiation through antagonizing miR-148a-3p.
Yuan H, Xu X, Feng X, Zhu E, Zhou J, Wang G, Tian L, Wang B
Cell death and differentiation 2019 Oct;26(10):2029-2045
Cell death and differentiation 2019 Oct;26(10):2029-2045
Whole-Exome Sequencing Analysis Identified Novel Mutations in the TSPAN12 Gene in Chinese Families with Familial Exudative Vitreoretinopathy.
Yuan Y, Xu H, Zhang S, Zhang X, Zhang L, Yang Z
Genetic testing and molecular biomarkers 2019 Oct;23(10):722-727
Genetic testing and molecular biomarkers 2019 Oct;23(10):722-727
Turnover of bile acids in liver, serum and caecal content by high-fat diet feeding affects hepatic steatosis in rats.
Tang Y, Zhang J, Li J, Lei X, Xu D, Wang Y, Li C, Li X, Mao Y
Biochimica et biophysica acta. Molecular and cell biology of lipids 2019 Oct;1864(10):1293-1304
Biochimica et biophysica acta. Molecular and cell biology of lipids 2019 Oct;1864(10):1293-1304
CX-F9, a novel RSK2 inhibitor, suppresses cutaneous melanoma cells proliferation and metastasis through regulating autophagy.
Zhang X, Cai L, Zhao S, Long J, Li J, Wu L, Su J, Zhang J, Tao J, Zhou J, Chen X, Peng C
Biochemical pharmacology 2019 Oct;168:14-25
Biochemical pharmacology 2019 Oct;168:14-25
Novel ADAM-17 inhibitor ZLDI-8 inhibits the proliferation and metastasis of chemo-resistant non-small-cell lung cancer by reversing Notch and epithelial mesenchymal transition in vitro and in vivo.
Lu HY, Zu YX, Jiang XW, Sun XT, Liu TY, Li RL, Wu Q, Zhang YS, Zhao QC
Pharmacological research 2019 Oct;148:104406
Pharmacological research 2019 Oct;148:104406
RNA-Seq analysis of potential lncRNAs and genes for the anti-renal fibrotic effect of norcantharidin.
Xiao H, Liao Y, Tang C, Xiao Z, Luo H, Li J, Liu H, Sun L, Zeng D, Li Y
Journal of cellular biochemistry 2019 Oct;120(10):17354-17367
Journal of cellular biochemistry 2019 Oct;120(10):17354-17367
Neuroprotective effect of Vanillin on hypoxic-ischemic brain damage in neonatal rats.
Lan XB, Wang Q, Yang JM, Ma L, Zhang WJ, Zheng P, Sun T, Niu JG, Liu N, Yu JQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109196
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109196
Dehydroepiandrosterone alleviates E. Coli O157:H7-induced inflammation by preventing the activation of p38 MAPK and NF-κB pathways in mice peritoneal macrophages.
Zhao J, Cao J, Yu L, Ma H
Molecular immunology 2019 Oct;114:114-122
Molecular immunology 2019 Oct;114:114-122
Oncogenic ADAM28 induces gemcitabine resistance and predicts a poor prognosis in pancreatic cancer.
Wei L, Wen JY, Chen J, Ma XK, Wu DH, Chen ZH, Huang JL
World journal of gastroenterology 2019 Oct 7;25(37):5590-5603
World journal of gastroenterology 2019 Oct 7;25(37):5590-5603
Adipose tissue-derived omentin-1 attenuates arterial calcification via AMPK/Akt signaling pathway.
Xu F, Li FX, Lin X, Zhong JY, Wu F, Shan SK, Tan CM, Yuan LQ, Liao XB
Aging 2019 Oct 25;11(20):8760-8776
Aging 2019 Oct 25;11(20):8760-8776
ROS-mediated inactivation of the PI3K/AKT pathway is involved in the antigastric cancer effects of thioredoxin reductase-1 inhibitor chaetocin.
Wen C, Wang H, Wu X, He L, Zhou Q, Wang F, Chen S, Huang L, Chen J, Wang H, Ye W, Li W, Yang X, Liu H, Peng J
Cell death & disease 2019 Oct 24;10(11):809
Cell death & disease 2019 Oct 24;10(11):809
Fractionated irradiation of right thorax induces abscopal damage on testes leading to decline in fertility.
Zhang J, Yao D, Song Y, Pan Y, Zhu L, Bai Y, Xu Y, Zhang J, Shao C
Scientific reports 2019 Oct 23;9(1):15221
Scientific reports 2019 Oct 23;9(1):15221
HIF-1α contributes to Ang II-induced inflammatory cytokine production in podocytes.
Huang H, Fan Y, Gao Z, Wang W, Shao N, Zhang L, Yang Y, Zhu W, Chen Z, Hu J, Ding G
BMC pharmacology & toxicology 2019 Oct 17;20(1):59
BMC pharmacology & toxicology 2019 Oct 17;20(1):59
The interference of DEHP in precocious puberty of females mediated by the hypothalamic IGF-1/PI3K/Akt/mTOR signaling pathway.
Shao P, Wang Y, Zhang M, Wen X, Zhang J, Xu Z, Hu M, Jiang J, Liu T
Ecotoxicology and environmental safety 2019 Oct 15;181:362-369
Ecotoxicology and environmental safety 2019 Oct 15;181:362-369
High metabolic rate and stem cell characteristics of esophageal cancer stem-like cells depend on the Hsp27-AKT-HK2 pathway.
Liu CC, Chou KT, Hsu JW, Lin JH, Hsu TW, Yen DH, Hung SC, Hsu HS
International journal of cancer 2019 Oct 15;145(8):2144-2156
International journal of cancer 2019 Oct 15;145(8):2144-2156
Young Blood Rescues the Cognition of Alzheimer's Model Mice by Restoring the Hippocampal Cholinergic Circuit.
Xia E, Xu F, Hu C, Kumal JPP, Tang X, Mao D, Li Y, Wu D, Zhang R, Wu S, Sun L
Neuroscience 2019 Oct 1;417:57-69
Neuroscience 2019 Oct 1;417:57-69
PPAR-δ of orange-spotted grouper exerts antiviral activity against fish virus and regulates interferon signaling and inflammatory factors.
Wang Y, Yu Y, Wang Q, Wei S, Wang S, Qin Q, Yang M
Fish & shellfish immunology 2019 Nov;94:38-49
Fish & shellfish immunology 2019 Nov;94:38-49
Piperine as a neuroprotective functional component in rats with cerebral ischemic injury.
Hua S, Liu J, Zhang Y, Li J, Zhang X, Dong L, Zhao Y, Fu X
Food science & nutrition 2019 Nov;7(11):3443-3451
Food science & nutrition 2019 Nov;7(11):3443-3451
O‑GlcNAc modification influences endometrial receptivity by promoting endometrial cell proliferation, migration and invasion.
Han X, Li X, Liu H, Zhang H, Li A, Dong M, Xu Y, Yan B, Sui L, Kong Y
Oncology reports 2019 Nov;42(5):2065-2074
Oncology reports 2019 Nov;42(5):2065-2074
Niban protein regulates apoptosis in HK-2 cells via caspase-dependent pathway.
Tang S, Wang J, Liu J, Huang Y, Zhou Y, Yang S, Zhang W, Yang M, Zhang H
Renal failure 2019 Nov;41(1):455-466
Renal failure 2019 Nov;41(1):455-466
Cadmium regulates von Willebrand factor and occludin expression in glomerular endothelial cells of mice in a TNF-α-dependent manner.
Sun Z, Xie Q, Pan J, Niu N
Renal failure 2019 Nov;41(1):354-362
Renal failure 2019 Nov;41(1):354-362
Wnt1 silencing enhances neurotoxicity induced by paraquat and maneb in SH-SY5Y cells.
Huang C, Ma J, Li BX, Sun Y
Experimental and therapeutic medicine 2019 Nov;18(5):3643-3649
Experimental and therapeutic medicine 2019 Nov;18(5):3643-3649
Propionate relieves pentylenetetrazol-induced seizures, consequent mitochondrial disruption, neuron necrosis and neurological deficits in mice.
Cheng Y, Mai Q, Zeng X, Wang H, Xiao Y, Tang L, Li J, Zhang Y, Ding H
Biochemical pharmacology 2019 Nov;169:113607
Biochemical pharmacology 2019 Nov;169:113607
Iron dysregulation in vascular dementia: Focused on the AMPK/autophagy pathway.
Huo T, Jia Y, Yin C, Luo X, Zhao J, Wang Z, Lv P
Brain research bulletin 2019 Nov;153:305-313
Brain research bulletin 2019 Nov;153:305-313
Identification of predictors of drug sensitivity using patient-derived models of esophageal squamous cell carcinoma.
Su D, Zhang D, Jin J, Ying L, Han M, Chen K, Li B, Wu J, Xie Z, Zhang F, Lin Y, Cheng G, Li JY, Huang M, Wang J, Wang K, Zhang J, Li F, Xiong L, Futreal A, Mao W
Nature communications 2019 Nov 7;10(1):5076
Nature communications 2019 Nov 7;10(1):5076
Hypertension-associated mitochondrial DNA 4401A>G mutation caused the aberrant processing of tRNAMet, all 8 tRNAs and ND6 mRNA in the light-strand transcript.
Zhao X, Cui L, Xiao Y, Mao Q, Aishanjiang M, Kong W, Liu Y, Chen H, Hong F, Jia Z, Wang M, Jiang P, Guan MX
Nucleic acids research 2019 Nov 4;47(19):10340-10356
Nucleic acids research 2019 Nov 4;47(19):10340-10356
Dexmedetomidine inhibits neuronal apoptosis by inducing Sigma-1 receptor signaling in cerebral ischemia-reperfusion injury.
Zhai M, Liu C, Li Y, Zhang P, Yu Z, Zhu H, Zhang L, Zhang Q, Wang J, Wang J
Aging 2019 Nov 4;11(21):9556-9568
Aging 2019 Nov 4;11(21):9556-9568
Oroxin B Induces Apoptosis by Down-Regulating MicroRNA-221 Resulting in the Inactivation of the PTEN/PI3K/AKT Pathway in Liver Cancer.
Li N, Men W, Zheng Y, Wang H, Meng X
Molecules (Basel, Switzerland) 2019 Nov 30;24(23)
Molecules (Basel, Switzerland) 2019 Nov 30;24(23)
PP2Ac Modulates AMPK-Mediated Induction of Autophagy in Mycobacterium bovis-Infected Macrophages.
Hussain T, Zhao D, Shah SZA, Sabir N, Wang J, Liao Y, Song Y, Hussain Mangi M, Yao J, Dong H, Yang L, Zhou X
International journal of molecular sciences 2019 Nov 29;20(23)
International journal of molecular sciences 2019 Nov 29;20(23)
Protrudin modulates seizure activity through GABA(A) receptor regulation.
Lu X, Yang Y, Zhou R, Li Y, Yang Y, Wang X
Cell death & disease 2019 Nov 27;10(12):897
Cell death & disease 2019 Nov 27;10(12):897
Folic acid delays age-related cognitive decline in senescence-accelerated mouse prone 8: alleviating telomere attrition as a potential mechanism.
Lv X, Wang X, Wang Y, Zhou D, Li W, Wilson JX, Chang H, Huang G
Aging 2019 Nov 22;11(22):10356-10373
Aging 2019 Nov 22;11(22):10356-10373
Dose-Dependent Effects of Triclocarban Exposure on Lipid Homeostasis in Rats.
Dong M, Xu X, Huang Q, Lei H, Xu G, Ma J, Hatzakis E, Wang X, Zhang L
Chemical research in toxicology 2019 Nov 18;32(11):2320-2328
Chemical research in toxicology 2019 Nov 18;32(11):2320-2328
Inhibition of Bcl-2 Synergistically Enhances the Antileukemic Activity of Midostaurin and Gilteritinib in Preclinical Models of FLT3-Mutated Acute Myeloid Leukemia.
Ma J, Zhao S, Qiao X, Knight T, Edwards H, Polin L, Kushner J, Dzinic SH, White K, Wang G, Zhao L, Lin H, Wang Y, Taub JW, Ge Y
Clinical cancer research : an official journal of the American Association for Cancer Research 2019 Nov 15;25(22):6815-6826
Clinical cancer research : an official journal of the American Association for Cancer Research 2019 Nov 15;25(22):6815-6826
Chitosan Ameliorates DSS-Induced Ulcerative Colitis Mice by Enhancing Intestinal Barrier Function and Improving Microflora.
Wang J, Zhang C, Guo C, Li X
International journal of molecular sciences 2019 Nov 15;20(22)
International journal of molecular sciences 2019 Nov 15;20(22)
Circ-ASH2L promotes tumor progression by sponging miR-34a to regulate Notch1 in pancreatic ductal adenocarcinoma.
Chen Y, Li Z, Zhang M, Wang B, Ye J, Zhang Y, Tang D, Ma D, Jin W, Li X, Wang S
Journal of experimental & clinical cancer research : CR 2019 Nov 12;38(1):466
Journal of experimental & clinical cancer research : CR 2019 Nov 12;38(1):466
Protective effects of Clec11a in islets against lipotoxicity via modulation of proliferation and lipid metabolism in mice.
Shi R, Hu J, Li W, Wang Z, Pan Y, Bai M, Mao W, Wang X, Zhong M, Yuan Y, Lau J, Sun Z, Zhao S
Experimental cell research 2019 Nov 1;384(1):111613
Experimental cell research 2019 Nov 1;384(1):111613
Melatonin protects against COPD by attenuating apoptosis and endoplasmic reticulum stress via upregulating SIRT1 expression in rats.
He B, Zhang W, Qiao J, Peng Z, Chai X
Canadian journal of physiology and pharmacology 2019 May;97(5):386-391
Canadian journal of physiology and pharmacology 2019 May;97(5):386-391
Functional analysis of the CXCR1a gene response to SGIV viral infection in grouper.
Wang Q, Yang M, Li C, Wang S, Wang Y, Lin F, Zheng L, Yu Y, Qin Q
Fish & shellfish immunology 2019 May;88:217-224
Fish & shellfish immunology 2019 May;88:217-224
A novel tumor suppressor SPINK5 targets Wnt/β-catenin signaling pathway in esophageal cancer.
Wang Q, Lv Q, Bian H, Yang L, Guo KL, Ye SS, Dong XF, Tao LL
Cancer medicine 2019 May;8(5):2360-2371
Cancer medicine 2019 May;8(5):2360-2371
Microglial LOX-1/MAPKs/NF-κB positive loop promotes the vicious cycle of neuroinflammation and neural injury.
Ge X, Zhang DM, Li MM, Zhang Y, Zhu XY, Zhou Y, Peng X, Shen AG
International immunopharmacology 2019 May;70:187-200
International immunopharmacology 2019 May;70:187-200
Activation of Nrf2 signaling by Icariin protects against 6-OHDA-induced neurotoxicity.
Zhu L, Li D, Chen C, Wang G, Shi J, Zhang F
Biotechnology and applied biochemistry 2019 May;66(3):465-471
Biotechnology and applied biochemistry 2019 May;66(3):465-471
Circular RNA cMras inhibits lung adenocarcinoma progression via modulating miR-567/PTPRG regulatory pathway.
Yu C, Tian F, Liu J, Su M, Wu M, Zhu X, Qian W
Cell proliferation 2019 May;52(3):e12610
Cell proliferation 2019 May;52(3):e12610
Eutopic endometrium from patients with endometriosis modulates the expression of CD36 and SIRP-α in peritoneal macrophages.
Xie Q, He H, Wu YH, Zou LJ, She XL, Xia XM, Wu XQ
The journal of obstetrics and gynaecology research 2019 May;45(5):1045-1057
The journal of obstetrics and gynaecology research 2019 May;45(5):1045-1057
Induced Pluripotent Stem Cells Regulate Triggering Receptor Expressed on Myeloid Cell-1 Expression and the p38 Mitogen-Activated Protein Kinase Pathway in Endotoxin-Induced Acute Lung Injury.
Su VY, Yang KY, Chiou SH, Chen NJ, Mo MH, Lin CS, Wang CT
Stem cells (Dayton, Ohio) 2019 May;37(5):631-639
Stem cells (Dayton, Ohio) 2019 May;37(5):631-639
HepaCAM Regulates Warburg Effect of Renal Cell Carcinoma via HIF-1α/NF-κB Signaling Pathway.
Fan Y, Ou L, Fan J, Li L, Wu X, Luo C, Gao Y, Niu L
Urology 2019 May;127:61-67
Urology 2019 May;127:61-67
Kallikrein 12 Regulates Innate Resistance of Murine Macrophages against Mycobacterium bovis Infection by Modulating Autophagy and Apoptosis.
Sabir N, Hussain T, Liao Y, Wang J, Song Y, Shahid M, Cheng G, Mangi MH, Yao J, Yang L, Zhao D, Zhou X
Cells 2019 May 5;8(5)
Cells 2019 May 5;8(5)
Predictable chronic mild stress promotes recovery from LPS-induced depression.
Dang R, Guo YY, Zhang K, Jiang P, Zhao MG
Molecular brain 2019 May 3;12(1):42
Molecular brain 2019 May 3;12(1):42
HMGB1 contributes to SASH1 methylation to attenuate astrocyte adhesion.
Wu R, Yan Y, Ma C, Chen H, Dong Z, Wang Y, Liu Y, Liu M, Yang L
Cell death & disease 2019 May 28;10(6):417
Cell death & disease 2019 May 28;10(6):417
Nilotinib: A Tyrosine Kinase Inhibitor Mediates Resistance to Intracellular Mycobacterium Via Regulating Autophagy.
Hussain T, Zhao D, Shah SZA, Sabir N, Wang J, Liao Y, Song Y, Dong H, Hussain Mangi M, Ni J, Yang L, Zhou X
Cells 2019 May 26;8(5)
Cells 2019 May 26;8(5)
Glucose metabolic alterations in hippocampus of diabetes mellitus rats and the regulation of aerobic exercise.
Li J, Liu B, Cai M, Lin X, Lou S
Behavioural brain research 2019 May 17;364:447-456
Behavioural brain research 2019 May 17;364:447-456
Efficient Production of Human Norovirus-Specific IgY in Egg Yolks by Vaccination of Hens with a Recombinant Vesicular Stomatitis Virus Expressing VP1 Protein.
Zhu Y, Ma Y, Lu M, Zhang Y, Li A, Liang X, Li J
Viruses 2019 May 16;11(5)
Viruses 2019 May 16;11(5)
Neuroprotective Effect of Swertiamain on Cerebral Ischemia/Reperfusion Injury by Inducing the Nrf2 Protective Pathway.
Wang H, Wei W, Lan X, Liu N, Li Y, Ma H, Sun T, Peng X, Zhuang C, Yu J
ACS chemical neuroscience 2019 May 15;10(5):2276-2286
ACS chemical neuroscience 2019 May 15;10(5):2276-2286
Role of OXCT1 in ovine adipose and preadipocyte differentiation.
Zeng J, Zhou SW, Zhao J, Jin MH, Kang DJ, Yang YX, Wang XL, Chen YL
Biochemical and biophysical research communications 2019 May 14;512(4):779-785
Biochemical and biophysical research communications 2019 May 14;512(4):779-785
Quantitative proteomic profiling of tumor-associated vascular endothelial cells in colorectal cancer.
Wang G, Yang Q, Li M, Zhang Y, Cai Y, Liang X, Fu Y, Xiao Z, Zhou M, Xie Z, Huang H, Huang Y, Chen Y, He Q, Peng F, Chen Z
Biology open 2019 May 13;8(5)
Biology open 2019 May 13;8(5)
Repurposing of omeprazole for oligodendrocyte differentiation and remyelination.
Zhu K, Sun J, Kang Z, Zou Z, Wu X, Wang Y, Wu G, Harris RA, Wang J
Brain research 2019 May 1;1710:33-42
Brain research 2019 May 1;1710:33-42
Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice.
He Y, Xia Z, Yu D, Wang J, Jin L, Huang D, Ye X, Li X, Zhang B
International immunopharmacology 2019 Mar;68:171-178
International immunopharmacology 2019 Mar;68:171-178
An isopentenyl-substituted flavonoid norartocarpin activates Nrf2 signalling pathway and prevents oxidative insults in human lung epithelial cells.
Yang WJ, He JX, Zhou MX, Huang M, Wang SQ, Wang XN, Lou HX, Ren DM, Shen T
Free radical research 2019 Mar;53(3):348-358
Free radical research 2019 Mar;53(3):348-358
NS38 is required for aquareovirus replication via interaction with viral core proteins and host eIF3A.
Zhang J, Guo H, Zhang F, Chen Q, Chang M, Fang Q
Virology 2019 Mar;529:216-225
Virology 2019 Mar;529:216-225
CSE1L participates in regulating cell mitosis in human seminoma.
Liu C, Wei J, Xu K, Sun X, Zhang H, Xiong C
Cell proliferation 2019 Mar;52(2):e12549
Cell proliferation 2019 Mar;52(2):e12549
The endogenous retrovirus-derived long noncoding RNA TROJAN promotes triple-negative breast cancer progression via ZMYND8 degradation.
Jin X, Xu XE, Jiang YZ, Liu YR, Sun W, Guo YJ, Ren YX, Zuo WJ, Hu X, Huang SL, Shen HJ, Lan F, He YF, Hu GH, Di GH, He XH, Li DQ, Liu S, Yu KD, Shao ZM
Science advances 2019 Mar;5(3):eaat9820
Science advances 2019 Mar;5(3):eaat9820
Regulation of Neurotransmitter Release by Amyloid Precursor Protein Through Synapsin Phosphorylation.
Liu A, Zhang Y, Han L, He G, Xie W, Zhou Z, Jia Z
Neurochemical research 2019 Mar;44(3):683-691
Neurochemical research 2019 Mar;44(3):683-691
MicroRNA‑223 promotes osteoblast differentiation of MC3T3‑E1 cells by targeting histone deacetylase 2.
Chen J, He G, Wang Y, Cai D
International journal of molecular medicine 2019 Mar;43(3):1513-1521
International journal of molecular medicine 2019 Mar;43(3):1513-1521
Wnt7a predicts poor prognosis, and contributes to growth and metastasis in tongue squamous cell carcinoma.
Jia B, Qiu X, Chu H, Sun X, Xu S, Zhao X, Zhao J
Oncology reports 2019 Mar;41(3):1749-1758
Oncology reports 2019 Mar;41(3):1749-1758
LncRNA EPB41L4A-AS1 regulates glycolysis and glutaminolysis by mediating nucleolar translocation of HDAC2.
Liao M, Liao W, Xu N, Li B, Liu F, Zhang S, Wang Y, Wang S, Zhu Y, Chen D, Xie W, Jiang Y, Cao L, Yang BB, Zhang Y
EBioMedicine 2019 Mar;41:200-213
EBioMedicine 2019 Mar;41:200-213
The selective HDAC6 inhibitor Nexturastat A induces apoptosis, overcomes drug resistance and inhibits tumor growth in multiple myeloma.
Sun X, Xie Y, Sun X, Yao Y, Li H, Li Z, Yao R, Xu K
Bioscience reports 2019 Mar 29;39(3)
Bioscience reports 2019 Mar 29;39(3)
iTRAQ-based quantitative proteomics reveals the neuroprotection of rhubarb in experimental intracerebral hemorrhage.
Liu T, Zhou J, Cui H, Li P, Luo J, Li T, He F, Wang Y, Tang T
Journal of ethnopharmacology 2019 Mar 25;232:244-254
Journal of ethnopharmacology 2019 Mar 25;232:244-254
MicroRNA-596 acts as a tumor suppressor in gastric cancer and is upregulated by promotor demethylation.
Zhang Z, Dai DQ
World journal of gastroenterology 2019 Mar 14;25(10):1224-1237
World journal of gastroenterology 2019 Mar 14;25(10):1224-1237
Hypoxic BMSC-derived exosomal miRNAs promote metastasis of lung cancer cells via STAT3-induced EMT.
Zhang X, Sai B, Wang F, Wang L, Wang Y, Zheng L, Li G, Tang J, Xiang J
Molecular cancer 2019 Mar 13;18(1):40
Molecular cancer 2019 Mar 13;18(1):40
Sericin Nerve Guidance Conduit Delivering Therapeutically Repurposed Clobetasol for Functional and Structural Regeneration of Transected Peripheral Nerves.
Zhang L, Yang W, Xie H, Wang H, Wang J, Su Q, Li X, Song Y, Wang G, Wang L, Wang Z
ACS biomaterials science & engineering 2019 Mar 11;5(3):1426-1439
ACS biomaterials science & engineering 2019 Mar 11;5(3):1426-1439
The methionine salvage pathway-involving ADI1 inhibits hepatoma growth by epigenetically altering genes expression via elevating S-adenosylmethionine.
Chu YD, Lai HY, Pai LM, Huang YH, Lin YH, Liang KH, Yeh CT
Cell death & disease 2019 Mar 11;10(3):240
Cell death & disease 2019 Mar 11;10(3):240
S-1-Propenylcysteine augments BACH1 degradation and heme oxygenase 1 expression in a nitric oxide-dependent manner in endothelial cells.
Tsuneyoshi T, Kunimura K, Morihara N
Nitric oxide : biology and chemistry 2019 Mar 1;84:22-29
Nitric oxide : biology and chemistry 2019 Mar 1;84:22-29
The role of autophagy in the overexpression of MUC5AC in patients with chronic rhinosinusitis.
Ye Y, Zhao J, Ye J, Jiang X, Liu H, Xie Y, Zhang J, Luo Q
International immunopharmacology 2019 Jun;71:169-180
International immunopharmacology 2019 Jun;71:169-180
Acid sphingomyelinase mediates the noise-induced liver disorder in mice.
Meng X, Gu Z, Xie X, Su Y, Zhang X, Ma H, Guo Y, Liu X, Cheng Y, Chang Y, Bao J
Clinical and experimental pharmacology & physiology 2019 Jun;46(6):556-566
Clinical and experimental pharmacology & physiology 2019 Jun;46(6):556-566
Upregulated histamine receptor H3 promotes tumor growth and metastasis in hepatocellular carcinoma.
Yu D, Zhao J, Wang Y, Hu J, Zhao Q, Li J, Zhu J
Oncology reports 2019 Jun;41(6):3347-3354
Oncology reports 2019 Jun;41(6):3347-3354
Clock mutant promotes osteoarthritis by inhibiting the acetylation of NFκB.
Yuan G, Xu L, Cai T, Hua B, Sun N, Yan Z, Lu C, Qian R
Osteoarthritis and cartilage 2019 Jun;27(6):922-931
Osteoarthritis and cartilage 2019 Jun;27(6):922-931
Cell survival controlled by lens-derived Sema3A-Nrp1 is vital on caffeine-suppressed corneal innervation during chick organogenesis.
Wang G, Jiang LM, Tan BY, Li PZ, Zhang PL, Zhang Y, Cheng X, Ma ZL, Li ZJ, Brand-Saberi B, Yang X
Journal of cellular physiology 2019 Jun;234(6):9826-9838
Journal of cellular physiology 2019 Jun;234(6):9826-9838
Ghrelin regulates sepsis‑induced rat acute gastric injury.
Li B, Lin Q, Guo H, Liu L, Li Y
Molecular medicine reports 2019 Jun;19(6):5424-5432
Molecular medicine reports 2019 Jun;19(6):5424-5432
Bronchial epithelial cell extracellular vesicles ameliorate epithelial-mesenchymal transition in COPD pathogenesis by alleviating M2 macrophage polarization.
He S, Chen D, Hu M, Zhang L, Liu C, Traini D, Grau GE, Zeng Z, Lu J, Zhou G, Xie L, Sun S
Nanomedicine : nanotechnology, biology, and medicine 2019 Jun;18:259-271
Nanomedicine : nanotechnology, biology, and medicine 2019 Jun;18:259-271
YWHA/14-3-3 proteins recognize phosphorylated TFEB by a noncanonical mode for controlling TFEB cytoplasmic localization.
Xu Y, Ren J, He X, Chen H, Wei T, Feng W
Autophagy 2019 Jun;15(6):1017-1030
Autophagy 2019 Jun;15(6):1017-1030
GDF-15 promotes mitochondrial function and proliferation in neuronal HT22 cells.
Liu H, Liu J, Si L, Guo C, Liu W, Liu Y
Journal of cellular biochemistry 2019 Jun;120(6):10530-10547
Journal of cellular biochemistry 2019 Jun;120(6):10530-10547
circ-CSPP1 promotes proliferation, invasion and migration of ovarian cancer cells by acting as a miR-1236-3p sponge.
Li QH, Liu Y, Chen S, Zong ZH, Du YP, Sheng XJ, Zhao Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jun;114:108832
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jun;114:108832
Site-Specific Immobilization of β(2)-AR Using O(6)-Benzylguanine Derivative-Functionalized Supporter for High-Throughput Receptor-Targeting Lead Discovery.
Wang J, Wang Y, Liu J, Li Q, Yin G, Zhang Y, Xiao C, Fan T, Zhao X, Zheng X
Analytical chemistry 2019 Jun 4;91(11):7385-7393
Analytical chemistry 2019 Jun 4;91(11):7385-7393
Pseudogene RACGAP1P activates RACGAP1/Rho/ERK signalling axis as a competing endogenous RNA to promote hepatocellular carcinoma early recurrence.
Wang MY, Chen DP, Qi B, Li MY, Zhu YY, Yin WJ, He L, Yu Y, Li ZY, Lin L, Yang F, Lin ZR, Liu JQ
Cell death & disease 2019 Jun 3;10(6):426
Cell death & disease 2019 Jun 3;10(6):426
iTRAQ-based proteomics analysis reveals the deregulated proteins related to liver toxicity induced by melamine with or without cyanuric acid in mice.
Yin RH, Huang C, Yuan J, Li W, Yin RL, Li HS, Dong Q, Li XT, Bai WL
Ecotoxicology and environmental safety 2019 Jun 15;174:618-629
Ecotoxicology and environmental safety 2019 Jun 15;174:618-629
Transection of the cervical sympathetic trunk inhibits the progression of pulmonary arterial hypertension via ERK-1/2 Signalling.
Zhao Y, Xiang R, Peng X, Dong Q, Li D, Yu G, Xiao L, Qin S, Huang W
Respiratory research 2019 Jun 14;20(1):121
Respiratory research 2019 Jun 14;20(1):121
Design and Synthesis of Potent, Selective Inhibitors of Protein Arginine Methyltransferase 4 against Acute Myeloid Leukemia.
Guo Z, Zhang Z, Yang H, Cao D, Xu X, Zheng X, Chen D, Wang Q, Li Y, Li J, Du Z, Wang X, Chen L, Ding J, Shen J, Geng M, Huang X, Xiong B
Journal of medicinal chemistry 2019 Jun 13;62(11):5414-5433
Journal of medicinal chemistry 2019 Jun 13;62(11):5414-5433
The long non-coding RNA H19 induces hypoxia/reoxygenation injury by up-regulating autophagy in the hepatoma carcinoma cells.
Cui C, Li Z, Wu D
Biological research 2019 Jun 13;52(1):32
Biological research 2019 Jun 13;52(1):32
Role of PM(2.5) in the development and progression of COPD and its mechanisms.
Zhao J, Li M, Wang Z, Chen J, Zhao J, Xu Y, Wei X, Wang J, Xie J
Respiratory research 2019 Jun 13;20(1):120
Respiratory research 2019 Jun 13;20(1):120
Epidural adipose tissue-derived mesenchymal stem cell activation induced by lung cancer cells promotes malignancy and EMT of lung cancer.
Wang Y, Chu Y, Ren X, Xiang H, Xi Y, Ma X, Zhu K, Guo Z, Zhou C, Zhang G, Chen B
Stem cell research & therapy 2019 Jun 13;10(1):168
Stem cell research & therapy 2019 Jun 13;10(1):168
The up-regulation of two identified wound healing specific proteins-HSP70 and lysozyme in regenerated Eisenia fetida through transcriptome analysis.
Yang Y, Sun Y, Zhang N, Li J, Zhang C, Duan X, Ding Y, Zhao R, Zheng Z, Geng D, Sun Y
Journal of ethnopharmacology 2019 Jun 12;237:64-73
Journal of ethnopharmacology 2019 Jun 12;237:64-73
Reduction of SIRT1 blunts the protective effects of ischemic post-conditioning in diabetic mice by impairing the Akt signaling pathway.
Ding M, Hu L, Yang H, Gao C, Zeng K, Yu M, Feng J, Qiu J, Liu C, Fu F, Li Y
Biochimica et biophysica acta. Molecular basis of disease 2019 Jun 1;1865(6):1677-1689
Biochimica et biophysica acta. Molecular basis of disease 2019 Jun 1;1865(6):1677-1689
MiR-664-2 impacts pubertal development in a precocious-puberty rat model through targeting the NMDA receptor-1†.
Ju M, Yang L, Zhu J, Chen Z, Zhang M, Yu J, Tian Z
Biology of reproduction 2019 Jun 1;100(6):1536-1548
Biology of reproduction 2019 Jun 1;100(6):1536-1548
Protective effects of pyrroloquinoline quinine against oxidative stress-induced cellular senescence and inflammation in human renal tubular epithelial cells via Keap1/Nrf2 signaling pathway.
Wang Z, Han N, Zhao K, Li Y, Chi Y, Wang B
International immunopharmacology 2019 Jul;72:445-453
International immunopharmacology 2019 Jul;72:445-453
Metabolism-induced tumor activator 1 (MITA1), an Energy Stress-Inducible Long Noncoding RNA, Promotes Hepatocellular Carcinoma Metastasis.
Ma M, Xu H, Liu G, Wu J, Li C, Wang X, Zhang S, Xu H, Ju S, Cheng W, Dai L, Wei Y, Tian Y, Fu X
Hepatology (Baltimore, Md.) 2019 Jul;70(1):215-230
Hepatology (Baltimore, Md.) 2019 Jul;70(1):215-230
Exogenous hydrogen sulfide mitigates LPS + ATP-induced inflammation by inhibiting NLRP3 inflammasome activation and promoting autophagy in L02 cells.
Wu D, Zhong P, Wang J, Wang H
Molecular and cellular biochemistry 2019 Jul;457(1-2):145-156
Molecular and cellular biochemistry 2019 Jul;457(1-2):145-156
Echinacoside Alleviates Hypoxic-Ischemic Brain Injury in Neonatal Rat by Enhancing Antioxidant Capacity and Inhibiting Apoptosis.
Wei W, Lan XB, Liu N, Yang JM, Du J, Ma L, Zhang WJ, Niu JG, Sun T, Yu JQ
Neurochemical research 2019 Jul;44(7):1582-1592
Neurochemical research 2019 Jul;44(7):1582-1592
Normoxia is not favorable for maintaining stemness of human endothelial progenitor cells.
Lin Y, Liu B, Deng T, Zhong J, Feng Z, Zeng Q, Huang G, Chen Z
Stem cell research 2019 Jul;38:101464
Stem cell research 2019 Jul;38:101464
GSTO1 acts as a mediator in sodium fluoride-induced alterations of learning and memory related factors expressions in the hippocampus cell line.
Wang J, Gao Y, Cheng X, Yang J, Zhao Y, Xu H, Zhu Y, Yan Z, Manthari RK, Ommati MM, Wang J
Chemosphere 2019 Jul;226:201-209
Chemosphere 2019 Jul;226:201-209
c‑Jun N‑terminal kinase/transforming growth factor‑β/Smad3 pathway: Is it associated with endoplasmic reticulum stress‑mediated renal interstitial fibrosis?
Liu Y, Shen P, Zhou Y, Tang L, Chai H
Molecular medicine reports 2019 Jul;20(1):755-762
Molecular medicine reports 2019 Jul;20(1):755-762
Toxicity mechanism of sevoflurane in neural stem cells of rats through DNA methylation.
Wang K, Tian Y, Zhang Y, Li X, Wei X, Hu H, Xu S
Experimental and therapeutic medicine 2019 Jul;18(1):237-241
Experimental and therapeutic medicine 2019 Jul;18(1):237-241
Aloperine suppresses human pulmonary vascular smooth muscle cell proliferation via inhibiting inflammatory response.
Chang Z, Zhang P, Zhang M, Jun F, Hu Z, Yang J, Wu Y, Zhou R
The Chinese journal of physiology 2019 Jul-Aug;62(4):157-165
The Chinese journal of physiology 2019 Jul-Aug;62(4):157-165
TRIM28 protects CARM1 from proteasome-mediated degradation to prevent colorectal cancer metastasis.
Cui J, Hu J, Ye Z, Fan Y, Li Y, Wang G, Wang L, Wang Z
Science bulletin 2019 Jul 30;64(14):986-997
Science bulletin 2019 Jul 30;64(14):986-997
Deciphering novel biomarkers of lymph node metastasis of thyroid papillary microcarcinoma using proteomic analysis of ultrasound-guided fine-needle aspiration biopsy samples.
Lin P, Yao Z, Sun Y, Li W, Liu Y, Liang K, Liu Y, Qin J, Hou X, Chen L
Journal of proteomics 2019 Jul 30;204:103414
Journal of proteomics 2019 Jul 30;204:103414
Precise and systematic survey of the efficacy of multicomponent drugs against functional dyspepsia.
Wei J, Man Q, Guo F, Xian M, Wang T, Tang C, Zhang Y, Li D, Tang D, Yang H, Huang L
Scientific reports 2019 Jul 24;9(1):10713
Scientific reports 2019 Jul 24;9(1):10713
Nek2 augments sorafenib resistance by regulating the ubiquitination and localization of β-catenin in hepatocellular carcinoma.
Deng L, Sun J, Chen X, Liu L, Wu D
Journal of experimental & clinical cancer research : CR 2019 Jul 18;38(1):316
Journal of experimental & clinical cancer research : CR 2019 Jul 18;38(1):316
miR-629-5p promotes growth and metastasis of hepatocellular carcinoma by activating β-catenin.
Tao X, Yang X, Wu K, Yang L, Huang Y, Jin Q, Chen S
Experimental cell research 2019 Jul 15;380(2):124-130
Experimental cell research 2019 Jul 15;380(2):124-130
Mitophagy is a protective response against oxidative damage in bone marrow mesenchymal stem cells.
Fan P, Yu XY, Xie XH, Chen CH, Zhang P, Yang C, Peng X, Wang YT
Life sciences 2019 Jul 15;229:36-45
Life sciences 2019 Jul 15;229:36-45
Multi-walled carbon nanotubes promoted lipid accumulation in human aortic smooth muscle cells.
Yang H, Li J, Yang C, Liu H, Cao Y
Toxicology and applied pharmacology 2019 Jul 1;374:11-19
Toxicology and applied pharmacology 2019 Jul 1;374:11-19
Hypericum perforatum L. supplementation protects sciatic nerve injury-induced apoptotic, inflammatory and oxidative damage to muscle, blood and brain in rats.
Uslusoy F, Nazıroğlu M, Övey İS, Sönmez TT
The Journal of pharmacy and pharmacology 2019 Jan;71(1):83-92
The Journal of pharmacy and pharmacology 2019 Jan;71(1):83-92
S1P promotes inflammation-induced tube formation by HLECs via the S1PR1/NF-κB pathway.
Zheng Z, Zeng YZ, Ren K, Zhu X, Tan Y, Li Y, Li Q, Yi GH
International immunopharmacology 2019 Jan;66:224-235
International immunopharmacology 2019 Jan;66:224-235
Overexpression of CDCA8 promotes the malignant progression of cutaneous melanoma and leads to poor prognosis.
Ci C, Tang B, Lyu D, Liu W, Qiang D, Ji X, Qiu X, Chen L, Ding W
International journal of molecular medicine 2019 Jan;43(1):404-412
International journal of molecular medicine 2019 Jan;43(1):404-412
Regulation of host cell pyroptosis and cytokines production by Mycobacterium tuberculosis effector PPE60 requires LUBAC mediated NF-κB signaling.
Gong Z, Kuang Z, Li H, Li C, Ali MK, Huang F, Li P, Li Q, Huang X, Ren S, Li J, Xie J
Cellular immunology 2019 Jan;335:41-50
Cellular immunology 2019 Jan;335:41-50
Induction of Endoplasmic Reticulum Stress by Cadmium and Its Regulation on Nrf2 Signaling Pathway in Kidneys of Rats.
Chen ZJ, Chen JX, Wu LK, Li BY, Tian YF, Xian M, Huang ZP, Yu RA
Biomedical and environmental sciences : BES 2019 Jan;32(1):1-10
Biomedical and environmental sciences : BES 2019 Jan;32(1):1-10
Radioprotective effects of roxadustat (FG-4592) in haematopoietic system.
Zhang P, Du J, Zhao H, Cheng Y, Dong S, Yang Y, Li B, Gao F, Sun X, Cai J, Liu C
Journal of cellular and molecular medicine 2019 Jan;23(1):349-356
Journal of cellular and molecular medicine 2019 Jan;23(1):349-356
BPTF promotes hepatocellular carcinoma growth by modulating hTERT signaling and cancer stem cell traits.
Zhao X, Zheng F, Li Y, Hao J, Tang Z, Tian C, Yang Q, Zhu T, Diao C, Zhang C, Chen M, Hu S, Guo P, Zhang L, Liao Y, Yu W, Chen M, Zou L, Guo W, Deng W
Redox biology 2019 Jan;20:427-441
Redox biology 2019 Jan;20:427-441
PARP inhibitor re‑sensitizes Adriamycin resistant leukemia cells through DNA damage and apoptosis.
Wu J, Xiao S, Yuan M, Li Q, Xiao G, Wu W, Ouyang Y, Huang L, Yao C
Molecular medicine reports 2019 Jan;19(1):75-84
Molecular medicine reports 2019 Jan;19(1):75-84
Constitutive androstane receptor weakens the induction of panaxytriol on CYP3A4 by repressing the activation of pregnane X receptor.
Hu Q, Yao N, Wu J, Liu M, Liu F, Zhang H, Xiong Y, Xia C
Biochemical pharmacology 2019 Jan;159:32-39
Biochemical pharmacology 2019 Jan;159:32-39
DEP domain containing 1 predicts prognosis of hepatocellular carcinoma patients and regulates tumor proliferation and metastasis.
Qu D, Cui F, Lu D, Yang Y, Xu Y
Cancer science 2019 Jan;110(1):157-165
Cancer science 2019 Jan;110(1):157-165
Zerumbone inhibits migration in ESCC via promoting Rac1 ubiquitination.
Wang M, Niu J, Gao L, Gao Y, Gao S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:2447-2455
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:2447-2455
FS-7 inhibits MGC-803 cells growth in vitro and in vivo via down-regulating glycolysis.
Deng X, Li Z, Xiong R, Liu J, Liu R, Peng J, Chen Y, Lei X, Cao X, Zheng X, Xie Z, Tang G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:1659-1669
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:1659-1669
Nerve injury elevates functional Cav3.2 channels in superficial spinal dorsal horn.
Feng XJ, Ma LX, Jiao C, Kuang HX, Zeng F, Zhou XY, Cheng XE, Zhu MY, Zhang DY, Jiang CY, Liu T
Molecular pain 2019 Jan-Dec;15:1744806919836569
Molecular pain 2019 Jan-Dec;15:1744806919836569
DHA-phospholipids (DHA-PL) and EPA-phospholipids (EPA-PL) prevent intestinal dysfunction induced by chronic stress.
Cao W, Wang C, Chin Y, Chen X, Gao Y, Yuan S, Xue C, Wang Y, Tang Q
Food & function 2019 Jan 22;10(1):277-288
Food & function 2019 Jan 22;10(1):277-288
Differential response to lead toxicity in rat primary microglia and astrocytes.
Peng J, Zhou F, Wang Y, Xu Y, Zhang H, Zou F, Meng X
Toxicology and applied pharmacology 2019 Jan 15;363:64-71
Toxicology and applied pharmacology 2019 Jan 15;363:64-71
Melatonin protects against sepsis-induced cardiac dysfunction by regulating apoptosis and autophagy via activation of SIRT1 in mice.
Zhang WX, He BM, Wu Y, Qiao JF, Peng ZY
Life sciences 2019 Jan 15;217:8-15
Life sciences 2019 Jan 15;217:8-15
miR-429 and miR-424-5p inhibit cell proliferation and Ca(2+) influx by downregulating CaSR in pulmonary artery smooth muscle cells.
Li C, Qin F, Xue M, Lei Y, Hu F, Xu H, Sun G, Wang T, Guo M
American journal of physiology. Cell physiology 2019 Jan 1;316(1):C111-C120
American journal of physiology. Cell physiology 2019 Jan 1;316(1):C111-C120
Sulforaphane Improves Lipid Metabolism by Enhancing Mitochondrial Function and Biogenesis In Vivo and In Vitro.
Lei P, Tian S, Teng C, Huang L, Liu X, Wang J, Zhang Y, Li B, Shan Y
Molecular nutrition & food research 2019 Feb;63(4):e1800795
Molecular nutrition & food research 2019 Feb;63(4):e1800795
Citrate reduced oxidative damage in stem cells by regulating cellular redox signaling pathways and represent a potential treatment for oxidative stress-induced diseases.
Wu X, Dai H, Liu L, Xu C, Yin Y, Yi J, Bielec MD, Han Y, Li S
Redox biology 2019 Feb;21:101057
Redox biology 2019 Feb;21:101057
Strand break-induced replication fork collapse leads to C-circles, C-overhangs and telomeric recombination.
Zhang T, Zhang Z, Shengzhao G, Li X, Liu H, Zhao Y
PLoS genetics 2019 Feb;15(2):e1007925
PLoS genetics 2019 Feb;15(2):e1007925
Exogenous Tetranectin Protects Against 1-Methyl-4-Phenylpyridine-Induced Neurotoxicity by Inhibiting Apoptosis and Autophagy Through Ribosomal Protein S6 Kinase Beta-1.
Xie Q, Liu M, Yan YF, Shen X, Wang ES
World neurosurgery 2019 Feb;122:e375-e382
World neurosurgery 2019 Feb;122:e375-e382
Interferon-alpha promotes immunosuppression through IFNAR1/STAT1 signalling in head and neck squamous cell carcinoma.
Ma H, Yang W, Zhang L, Liu S, Zhao M, Zhou G, Wang L, Jin S, Zhang Z, Hu J
British journal of cancer 2019 Feb;120(3):317-330
British journal of cancer 2019 Feb;120(3):317-330
A coronary artery disease-associated tRNAThr mutation altered mitochondrial function, apoptosis and angiogenesis.
Jia Z, Zhang Y, Li Q, Ye Z, Liu Y, Fu C, Cang X, Wang M, Guan MX
Nucleic acids research 2019 Feb 28;47(4):2056-2074
Nucleic acids research 2019 Feb 28;47(4):2056-2074
Protective effect of oxytocin on LPS-induced acute lung injury in mice.
An X, Sun X, Hou Y, Yang X, Chen H, Zhang P, Wu J
Scientific reports 2019 Feb 26;9(1):2836
Scientific reports 2019 Feb 26;9(1):2836
Long noncoding RNA HOTAIR regulates autophagy via the miR-20b-5p/ATG7 axis in hepatic ischemia/reperfusion injury.
Tang B, Bao N, He G, Wang J
Gene 2019 Feb 20;686:56-62
Gene 2019 Feb 20;686:56-62
Carnosol as a Nrf2 Activator Improves Endothelial Barrier Function Through Antioxidative Mechanisms.
Li X, Zhang Q, Hou N, Li J, Liu M, Peng S, Zhang Y, Luo Y, Zhao B, Wang S, Zhang Y, Qiao Y
International journal of molecular sciences 2019 Feb 18;20(4)
International journal of molecular sciences 2019 Feb 18;20(4)
MiR-223-3p functions as a tumor suppressor in lung squamous cell carcinoma by miR-223-3p-mutant p53 regulatory feedback loop.
Luo P, Wang Q, Ye Y, Zhang J, Lu D, Cheng L, Zhou H, Xie M, Wang B
Journal of experimental & clinical cancer research : CR 2019 Feb 12;38(1):74
Journal of experimental & clinical cancer research : CR 2019 Feb 12;38(1):74
Autophagy inhibition potentiates the anti-angiogenic property of multikinase inhibitor anlotinib through JAK2/STAT3/VEGFA signaling in non-small cell lung cancer cells.
Liang L, Hui K, Hu C, Wen Y, Yang S, Zhu P, Wang L, Xia Y, Qiao Y, Sun W, Fei J, Chen T, Zhao F, Yang B, Jiang X
Journal of experimental & clinical cancer research : CR 2019 Feb 12;38(1):71
Journal of experimental & clinical cancer research : CR 2019 Feb 12;38(1):71
Protective Effect of Koumine, an Alkaloid from Gelsemium Sempervirens, on Injury Induced by H₂O₂ in IPEC-J2 Cells.
Yuan Z, Liang Z, Yi J, Chen X, Li R, Wu Y, Wu J, Sun Z
International journal of molecular sciences 2019 Feb 11;20(3)
International journal of molecular sciences 2019 Feb 11;20(3)
Blockade of glycolysis-dependent contraction by oroxylin a via inhibition of lactate dehydrogenase-a in hepatic stellate cells.
Wang F, Jia Y, Li M, Wang L, Shao J, Guo Q, Tan S, Ding H, Chen A, Zhang F, Zheng S
Cell communication and signaling : CCS 2019 Feb 11;17(1):11
Cell communication and signaling : CCS 2019 Feb 11;17(1):11
Identification of diterpenoid compounds that interfere with Fli-1 DNA binding to suppress leukemogenesis.
Liu T, Xia L, Yao Y, Yan C, Fan Y, Gajendran B, Yang J, Li YJ, Chen J, Filmus J, Spaner DE, Zacksenhaus E, Hao X, Ben-David Y
Cell death & disease 2019 Feb 11;10(2):117
Cell death & disease 2019 Feb 11;10(2):117
Nano-Gold Loaded with Resveratrol Enhance the Anti-Hepatoma Effect of Resveratrol In Vitro and In Vivo.
Zhang D, Zhang J, Zeng J, Li Z, Zuo H, Huang C, Zhao X
Journal of biomedical nanotechnology 2019 Feb 1;15(2):288-300
Journal of biomedical nanotechnology 2019 Feb 1;15(2):288-300
Protective effects of a neurokinin 1 receptor antagonist on airway epithelial mitochondria dysfunction in asthmatic mice via Nrf2/HO-1 activation.
Wang Z, Li M, Zhou Q, Shang Y
International immunopharmacology 2019 Dec;77:105952
International immunopharmacology 2019 Dec;77:105952
Propofol Attenuates Hypoxia/Reoxygenation-Induced Apoptosis and Autophagy in HK-2 Cells by Inhibiting JNK Activation.
Wang H, Peng X, Huang Y, Xiao Y, Wang Z, Zhan L
Yonsei medical journal 2019 Dec;60(12):1195-1202
Yonsei medical journal 2019 Dec;60(12):1195-1202
Effect of hydrogen-rich water on the Nrf2/ARE signaling pathway in rats with myocardial ischemia-reperfusion injury.
Li L, Liu T, Liu L, Li S, Zhang Z, Zhang R, Zhou Y, Liu F
Journal of bioenergetics and biomembranes 2019 Dec;51(6):393-402
Journal of bioenergetics and biomembranes 2019 Dec;51(6):393-402
Molecular mechanism of miR-204 regulates proliferation, apoptosis and autophagy of cervical cancer cells by targeting ATF2.
Li N, Guo X, Liu L, Wang L, Cheng R
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):2529-2535
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):2529-2535
Osteoadherin serves roles in the regulation of apoptosis and growth in MC3T3‑E1 osteoblast cells.
Hamaya E, Fujisawa T, Tamura M
International journal of molecular medicine 2019 Dec;44(6):2336-2344
International journal of molecular medicine 2019 Dec;44(6):2336-2344
Bexarotene Attenuates Focal Cerebral Ischemia-Reperfusion Injury via the Suppression of JNK/Caspase-3 Signaling Pathway.
Liu H, Liu S, Tian X, Wang Q, Rao J, Wang Y, Xiang F, Zheng H, Xu L, Dong Z
Neurochemical research 2019 Dec;44(12):2809-2820
Neurochemical research 2019 Dec;44(12):2809-2820
Design, synthesis and molecular mechanisms of novel dual inhibitors of heat shock protein 90/phosphoinositide 3-kinase alpha (Hsp90/PI3Kα) against cutaneous melanoma.
Qin F, Wang Y, Jiang X, Wang Y, Zhang N, Wen X, Wang L, Jiang Q, He G
Journal of enzyme inhibition and medicinal chemistry 2019 Dec;34(1):909-926
Journal of enzyme inhibition and medicinal chemistry 2019 Dec;34(1):909-926
Silencing ubiquitin-conjugating enzyme 2C inhibits proliferation and epithelial-mesenchymal transition in pancreatic ductal adenocarcinoma.
Wang X, Yin L, Yang L, Zheng Y, Liu S, Yang J, Cui H, Wang H
The FEBS journal 2019 Dec;286(24):4889-4909
The FEBS journal 2019 Dec;286(24):4889-4909
Hepatoprotective effects of zinc (II) via cytochrome P-450/reactive oxygen species and canonical apoptosis pathways after arsenite waterborne exposure in common carp.
Zhao H, Wang Y, Guo M, Fei D, Mu M, Yu H, Xing M
Chemosphere 2019 Dec;236:124869
Chemosphere 2019 Dec;236:124869
CircRhoC promotes tumorigenicity and progression in ovarian cancer by functioning as a miR-302e sponge to positively regulate VEGFA.
Wang LL, Zong ZH, Liu Y, Guan X, Chen S, Zhao Y
Journal of cellular and molecular medicine 2019 Dec;23(12):8472-8481
Journal of cellular and molecular medicine 2019 Dec;23(12):8472-8481
Protective effects of betaine on diabetic induced disruption of the male mice blood-testis barrier by regulating oxidative stress-mediated p38 MAPK pathways.
Jiang YP, Yang JM, Ye RJ, Liu N, Zhang WJ, Ma L, Zheng P, Niu JG, Liu P, Yu JQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109474
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109474
Glycogen phosphorylase B promotes ovarian cancer progression via Wnt/β-catenin signaling and is regulated by miR-133a-3p.
Zhou Y, Jin Z, Wang C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109449
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109449
Differential immune responses of C57BL/6 mice to infection by Salmonella enterica serovar Typhimurium strain SL1344, CVCC541 and CMCC50115.
Wei S, Huang J, Liu Z, Wang M, Zhang B, Lian Z, Guo Y, Han H
Virulence 2019 Dec;10(1):248-259
Virulence 2019 Dec;10(1):248-259
circPUM1 Promotes Tumorigenesis and Progression of Ovarian Cancer by Sponging miR-615-5p and miR-6753-5p.
Guan X, Zong ZH, Liu Y, Chen S, Wang LL, Zhao Y
Molecular therapy. Nucleic acids 2019 Dec 6;18:882-892
Molecular therapy. Nucleic acids 2019 Dec 6;18:882-892
Dietary Curcumin Supplementation Increases Antioxidant Capacity, Upregulates Nrf2 and Hmox1 Levels in the Liver of Piglet Model with Intrauterine Growth Retardation.
Niu Y, He J, Ahmad H, Shen M, Zhao Y, Gan Z, Zhang L, Zhong X, Wang C, Wang T
Nutrients 2019 Dec 5;11(12)
Nutrients 2019 Dec 5;11(12)
ATXN3 promotes breast cancer metastasis by deubiquitinating KLF4.
Zou H, Chen H, Zhou Z, Wan Y, Liu Z
Cancer letters 2019 Dec 28;467:19-28
Cancer letters 2019 Dec 28;467:19-28
Autophagy Attenuation Hampers Progesterone Synthesis during the Development of Pregnant Corpus Luteum.
Tang Z, Zhang Z, Zhang H, Wang Y, Zhang Y, Zhao J, Yang H, Wang Z
Cells 2019 Dec 27;9(1)
Cells 2019 Dec 27;9(1)
Dietary Dihydroartemisinin Supplementation Attenuates Hepatic Oxidative Damage of Weaned Piglets with Intrauterine Growth Retardation through the Nrf2/ARE Signaling Pathway.
Zhao Y, Niu Y, He J, Zhang L, Wang C, Wang T
Animals : an open access journal from MDPI 2019 Dec 13;9(12)
Animals : an open access journal from MDPI 2019 Dec 13;9(12)
LPS Inhibits Fatty Acid Absorption in Enterocytes through TNF-α Secreted by Macrophages.
Liu H, Kai L, Du H, Wang X, Wang Y
Cells 2019 Dec 12;8(12)
Cells 2019 Dec 12;8(12)
Icariin targets Nrf2 signaling to inhibit microglia-mediated neuroinflammation.
Zheng Y, Zhu G, He J, Wang G, Li D, Zhang F
International immunopharmacology 2019 Aug;73:304-311
International immunopharmacology 2019 Aug;73:304-311
Disubstituted Dithiolethione ACDT Exerts Neuroprotective Effects Against 6-Hydroxydopamine-Induced Oxidative Stress in SH-SY5Y Cells.
Betharia S, Rondόn-Ortiz AN, Brown DA
Neurochemical research 2019 Aug;44(8):1878-1892
Neurochemical research 2019 Aug;44(8):1878-1892
Abnormal serum vitamin A levels and retinoic acid receptor α expression patterns in children with anorectal malformation.
Wang Z, Wang Q, Gu C, Zhang J, Wang Y
Pediatric surgery international 2019 Aug;35(8):903-910
Pediatric surgery international 2019 Aug;35(8):903-910
Hypoxic postconditioning activates the Wnt/β-catenin pathway and protects against transient global cerebral ischemia through Dkk1 Inhibition and GSK-3β inactivation.
Zhan L, Liu D, Wen H, Hu J, Pang T, Sun W, Xu E
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Aug;33(8):9291-9307
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Aug;33(8):9291-9307
Exosomes from high glucose-treated macrophages activate glomerular mesangial cells via TGF-β1/Smad3 pathway in vivo and in vitro.
Zhu QJ, Zhu M, Xu XX, Meng XM, Wu YG
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Aug;33(8):9279-9290
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Aug;33(8):9279-9290
Bone marrow mesenchymal stem cells could reduce the toxic effects of hexavalent chromium on the liver by decreasing endoplasmic reticulum stress-mediated apoptosis via SIRT1/HIF-1α signaling pathway in rats.
Zhao Y, Yan J, Li AP, Zhang ZL, Li ZR, Guo KJ, Zhao KC, Ruan Q, Guo L
Toxicology letters 2019 Aug;310:31-38
Toxicology letters 2019 Aug;310:31-38
Knockdown of LncRNA SCAMP1 suppressed malignant biological behaviours of glioma cells via modulating miR-499a-5p/LMX1A/NLRC5 pathway.
Zong Z, Song Y, Xue Y, Ruan X, Liu X, Yang C, Zheng J, Cao S, Li Z, Liu Y
Journal of cellular and molecular medicine 2019 Aug;23(8):5048-5062
Journal of cellular and molecular medicine 2019 Aug;23(8):5048-5062
RING finger protein 10 is a potential drug target for diabetic vascular complications.
Li S, Yu G, Huang W, Wang R, Pu P, Chen M
Molecular medicine reports 2019 Aug;20(2):931-938
Molecular medicine reports 2019 Aug;20(2):931-938
Phenotypic transition of tumor cells between epithelial- and mesenchymal-like state during adaptation to acidosis.
Zhang Y, Xu L, Wang P, Jian H, Shi X, Jia M, Mo L, Hu Z, Li H, Li J
Cell cycle (Georgetown, Tex.) 2019 Aug;18(16):1938-1947
Cell cycle (Georgetown, Tex.) 2019 Aug;18(16):1938-1947
Bilirubin alleviates alum-induced peritonitis through inactivation of NLRP3 inflammasome.
Lin Y, Wang S, Yang Z, Gao L, Zhou Z, Yu P, Wu B
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Aug;116:108973
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Aug;116:108973
The expression of cerebrospinal fluid exosomal miR-630 plays an important role in the dysfunction of endothelial cells after subarachnoid hemorrhage.
Sun L, Zhang W, Li Z, Li M, Guo J, Wang H, Wang X
Scientific reports 2019 Aug 8;9(1):11510
Scientific reports 2019 Aug 8;9(1):11510
Cordycepin alleviates hepatic lipid accumulation by inducing protective autophagy via PKA/mTOR pathway.
Li T, Wen L, Cheng B
Biochemical and biophysical research communications 2019 Aug 27;516(3):632-638
Biochemical and biophysical research communications 2019 Aug 27;516(3):632-638
Brilliant Blue G Inhibits Inflammasome Activation and Reduces Disruption of Blood-Spinal Cord Barrier Induced by Spinal Cord Injury in Rats.
Zhou X, Yang Y, Wu L, Wang Y, Du C, Li C, Wang Z, Wang Y
Medical science monitor : international medical journal of experimental and clinical research 2019 Aug 24;25:6359-6366
Medical science monitor : international medical journal of experimental and clinical research 2019 Aug 24;25:6359-6366
miR-205-5p regulates epithelial-mesenchymal transition by targeting PTEN via PI3K/AKT signaling pathway in cisplatin-resistant nasopharyngeal carcinoma cells.
Zhang P, Lu X, Shi Z, Li X, Zhang Y, Zhao S, Liu H
Gene 2019 Aug 20;710:103-113
Gene 2019 Aug 20;710:103-113
Rho-kinase inhibitor attenuates airway mucus hypersecretion and inflammation partly by downregulation of IL-13 and the JNK1/2-AP1 signaling pathway.
Zhang W, Li X, Zhang Y
Biochemical and biophysical research communications 2019 Aug 20;516(2):571-577
Biochemical and biophysical research communications 2019 Aug 20;516(2):571-577
Selective ERK1/2 agonists isolated from Melia azedarach with potent anti-leukemic activity.
Wang N, Fan Y, Yuan CM, Song J, Yao Y, Liu W, Gajendran B, Zacksenhaus E, Li Y, Liu J, Hao XJ, Ben-David Y
BMC cancer 2019 Aug 2;19(1):764
BMC cancer 2019 Aug 2;19(1):764
MiR-146b accelerates osteoarthritis progression by targeting alpha-2-macroglobulin.
Liu X, Liu L, Zhang H, Shao Y, Chen Z, Feng X, Fang H, Zhao C, Pan J, Zhang H, Zeng C, Cai D
Aging 2019 Aug 17;11(16):6014-6028
Aging 2019 Aug 17;11(16):6014-6028
Identification of proteomic signatures associated with COPD frequent exacerbators.
Sun P, Ye R, Wang C, Bai S, Zhao L
Life sciences 2019 Aug 1;230:1-9
Life sciences 2019 Aug 1;230:1-9
Changes among TGF-β1(+) Breg cells and helper T cell subsets in a murine model of allergic rhinitis with prolonged OVA challenge.
Wang M, Gu Z, Yang J, Zhao H, Cao Z
International immunopharmacology 2019 Apr;69:347-357
International immunopharmacology 2019 Apr;69:347-357
CD36 plays a negative role in the regulation of lipophagy in hepatocytes through an AMPK-dependent pathway.
Li Y, Yang P, Zhao L, Chen Y, Zhang X, Zeng S, Wei L, Varghese Z, Moorhead JF, Chen Y, Ruan XZ
Journal of lipid research 2019 Apr;60(4):844-855
Journal of lipid research 2019 Apr;60(4):844-855
Netrin‑1 interference potentiates epithelial‑to‑mesenchymal transition through the PI3K/AKT pathway under the hypoxic microenvironment conditions of non‑small cell lung cancer.
Jin X, Luan H, Chai H, Yan L, Zhang J, Wang Q, Cao L
International journal of oncology 2019 Apr;54(4):1457-1465
International journal of oncology 2019 Apr;54(4):1457-1465
Simvastatin ameliorates total liver ischemia/reperfusion injury via KLF2-mediated mechanism in rats.
Liu Z, Lai CH, Zhang X, Luo J, Huang X, Qi X, Wang W, Zhong Z, Xiaoli F, Li L, Xiong Y, Senninger N, Wang Y, Ye Q, Ye S
Clinics and research in hepatology and gastroenterology 2019 Apr;43(2):171-178
Clinics and research in hepatology and gastroenterology 2019 Apr;43(2):171-178
High-mobility group box 1 protein modulated proliferation and radioresistance in esophageal squamous cell carcinoma.
Di X, He G, Chen H, Zhu C, Qin Q, Yan J, Zhang X, Sun X
Journal of gastroenterology and hepatology 2019 Apr;34(4):728-735
Journal of gastroenterology and hepatology 2019 Apr;34(4):728-735
Nicotinate-curcumin ameliorates cognitive impairment in diabetic rats by rescuing autophagic flux in CA1 hippocampus.
Gu HF, Li N, Tang YL, Yan CQ, Shi Z, Yi SN, Zhou HL, Liao DF, OuYang XP
CNS neuroscience & therapeutics 2019 Apr;25(4):430-441
CNS neuroscience & therapeutics 2019 Apr;25(4):430-441
CCL18 promotes the metastasis of squamous cell carcinoma of the head and neck through MTDH-NF-κB signalling pathway.
Qin Y, Wang J, Zhu G, Li G, Tan H, Chen C, Pi L, She L, Chen X, Wei M, Li Z, Liu Z, Huang D, Liu Y, Zhang X
Journal of cellular and molecular medicine 2019 Apr;23(4):2689-2701
Journal of cellular and molecular medicine 2019 Apr;23(4):2689-2701
SIRT5-mediated SDHA desuccinylation promotes clear cell renal cell carcinoma tumorigenesis.
Ma Y, Qi Y, Wang L, Zheng Z, Zhang Y, Zheng J
Free radical biology & medicine 2019 Apr;134:458-467
Free radical biology & medicine 2019 Apr;134:458-467
Changes in the levels of 12/15-lipoxygenase, apoptosis-related proteins and inflammatory factors in the cortex of diabetic rats and the neuroprotection of baicalein.
Li Y, Chen Q, Ran D, Wang H, Du W, Luo Y, Jiang W, Yang Y, Yang J
Free radical biology & medicine 2019 Apr;134:239-247
Free radical biology & medicine 2019 Apr;134:239-247
The toxicity of multi-walled carbon nanotubes (MWCNTs) to human endothelial cells: The influence of diameters of MWCNTs.
Zhao X, Chang S, Long J, Li J, Li X, Cao Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Apr;126:169-177
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Apr;126:169-177
Effects of myostatin deficiency on PGC-1α and FNDC5 expression in three different murine muscle types.
Bai Y, Bi H, Li L, Li J, Yu X, Ren H, Li Y, Ji Y, Li H, Wang H
Acta histochemica 2019 Apr;121(3):323-329
Acta histochemica 2019 Apr;121(3):323-329
Prolonged high-glucose exposure decreased SREBP-1/FASN/ACC in Schwann cells of diabetic mice via blocking PI3K/Akt pathway.
Zhu L, Du W, Liu Y, Cheng M, Wang X, Zhang C, Lv X, Li F, Zhao S, Hao J
Journal of cellular biochemistry 2019 Apr;120(4):5777-5789
Journal of cellular biochemistry 2019 Apr;120(4):5777-5789
MiRNA-29a modulates visceral hyperalgesia in irritable bowel syndrome by targeting HTR7.
Zhu H, Xiao X, Chai Y, Li D, Yan X, Tang H
Biochemical and biophysical research communications 2019 Apr 9;511(3):671-678
Biochemical and biophysical research communications 2019 Apr 9;511(3):671-678
Long non-coding RNA GBCDRlnc1 induces chemoresistance of gallbladder cancer cells by activating autophagy.
Cai Q, Wang S, Jin L, Weng M, Zhou D, Wang J, Tang Z, Quan Z
Molecular cancer 2019 Apr 5;18(1):82
Molecular cancer 2019 Apr 5;18(1):82
The Anticonvulsant Effects of Baldrinal on Pilocarpine-Induced convulsion in Adult Male Mice.
Zhang X, Li X, Liu N, Zheng P, Ma L, Guo F, Sun T, Zhou R, Yu J
Molecules (Basel, Switzerland) 2019 Apr 24;24(8)
Molecules (Basel, Switzerland) 2019 Apr 24;24(8)
Effects of agomelatine in rotenone-induced Parkinson's disease in rats.
Günaydın C, Avcı B, Bozkurt A, Önger ME, Balcı H, Bilge SS
Neuroscience letters 2019 Apr 23;699:71-76
Neuroscience letters 2019 Apr 23;699:71-76
Ginsenoside Rk1 induces cell cycle arrest and apoptosis in MDA-MB-231 triple negative breast cancer cells.
Hong Y, Fan D
Toxicology 2019 Apr 15;418:22-31
Toxicology 2019 Apr 15;418:22-31
The effect of di-2-ethylhexyl phthalate on inflammation and lipid metabolic disorder in rats.
Zhou L, Chen H, Xu Q, Han X, Zhao Y, Song X, Zhao T, Ye L
Ecotoxicology and environmental safety 2019 Apr 15;170:391-398
Ecotoxicology and environmental safety 2019 Apr 15;170:391-398
Transketolase (TKT) activity and nuclear localization promote hepatocellular carcinoma in a metabolic and a non-metabolic manner.
Qin Z, Xiang C, Zhong F, Liu Y, Dong Q, Li K, Shi W, Ding C, Qin L, He F
Journal of experimental & clinical cancer research : CR 2019 Apr 11;38(1):154
Journal of experimental & clinical cancer research : CR 2019 Apr 11;38(1):154
Microglial NLRP3 inflammasome activation mediates IL-1β release and contributes to central sensitization in a recurrent nitroglycerin-induced migraine model.
He W, Long T, Pan Q, Zhang S, Zhang Y, Zhang D, Qin G, Chen L, Zhou J
Journal of neuroinflammation 2019 Apr 10;16(1):78
Journal of neuroinflammation 2019 Apr 10;16(1):78
TCF7L1 indicates prognosis and promotes proliferation through activation of Keap1/NRF2 in gastric cancer.
Zhang B, Wu J, Cai Y, Luo M, Wang B, Gu Y
Acta biochimica et biophysica Sinica 2019 Apr 1;51(4):375-385
Acta biochimica et biophysica Sinica 2019 Apr 1;51(4):375-385
Inhibition of soluble epoxide hydrolase ameliorates hyperhomocysteinemia-induced hepatic steatosis by enhancing β-oxidation of fatty acid in mice.
Yao L, Cao B, Cheng Q, Cai W, Ye C, Liang J, Liu W, Tan L, Yan M, Li B, He J, Hwang SH, Zhang X, Wang C, Ai D, Hammock BD, Zhu Y
American journal of physiology. Gastrointestinal and liver physiology 2019 Apr 1;316(4):G527-G538
American journal of physiology. Gastrointestinal and liver physiology 2019 Apr 1;316(4):G527-G538
The PERK-EIF2α-ATF4 signaling branch regulates osteoblast differentiation and proliferation by PTH.
Zhang K, Wang M, Li Y, Li C, Tang S, Qu X, Feng N, Wu Y
American journal of physiology. Endocrinology and metabolism 2019 Apr 1;316(4):E590-E604
American journal of physiology. Endocrinology and metabolism 2019 Apr 1;316(4):E590-E604
High Expression of lncRNA AFAP1-AS1 Promotes the Progression of Colon Cancer and Predicts Poor Prognosis.
Bo H, Fan L, Li J, Liu Z, Zhang S, Shi L, Guo C, Li X, Liao Q, Zhang W, Zhou M, Xiang B, Li X, Li G, Xiong W, Zeng Z, Xiong F, Gong Z
Journal of Cancer 2018;9(24):4677-4683
Journal of Cancer 2018;9(24):4677-4683
Trio-Based Deep Sequencing Reveals a Low Incidence of Off-Target Mutations in the Offspring of Genetically Edited Goats.
Li C, Zhou S, Li Y, Li G, Ding Y, Li L, Liu J, Qu L, Sonstegard T, Huang X, Jiang Y, Chen Y, Petersen B, Wang X
Frontiers in genetics 2018;9:449
Frontiers in genetics 2018;9:449
Fangchinoline Ameliorates the Expressions of Angiogenic Molecule in Cerebral Ischemia Induced Neuronal Degeneration in Neonatal Rats.
Daicheng H, Shiwen X, Huaping Z, Yong L, Qianqian Z, Changxia H
Translational neuroscience 2018;9:117-122
Translational neuroscience 2018;9:117-122
Snx27 Deletion Promotes Recovery From Spinal Cord Injury by Neuroprotection and Reduces Macrophage/Microglia Proliferation.
Zeng Y, Wang N, Guo T, Zheng Q, Wang S, Wu S, Li X, Wu J, Chen Z, Xu H, Wang X, Lin B
Frontiers in neurology 2018;9:1059
Frontiers in neurology 2018;9:1059
Adipocytes fuel gastric cancer omental metastasis via PITPNC1-mediated fatty acid metabolic reprogramming.
Tan Y, Lin K, Zhao Y, Wu Q, Chen D, Wang J, Liang Y, Li J, Hu J, Wang H, Liu Y, Zhang S, He W, Huang Q, Hu X, Yao Z, Liang B, Liao W, Shi M
Theranostics 2018;8(19):5452-5468
Theranostics 2018;8(19):5452-5468
Th17 cell-derived IL-17A promoted tumor progression via STAT3/NF-κB/Notch1 signaling in non-small cell lung cancer.
Wang R, Yang L, Zhang C, Wang R, Zhang Z, He Q, Chen X, Zhang B, Qin Z, Wang L, Zhang Y
Oncoimmunology 2018;7(11):e1461303
Oncoimmunology 2018;7(11):e1461303
Long Noncoding RNA HOTTIP Promotes Mouse Hepatic Stellate Cell Activation via Downregulating miR-148a.
Li Z, Wang J, Zeng Q, Hu C, Zhang J, Wang H, Yan J, Li H, Yu Z
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(6):2814-2828
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(6):2814-2828
The FOXK1-CCDC43 Axis Promotes the Invasion and Metastasis of Colorectal Cancer Cells.
Wang J, Liu G, Liu M, Xiang L, Xiao Y, Zhu H, Wu X, Peng Y, Zhang W, Jiang P, Li A, Nan Q, Chen Y, Chen C, Cheng T, Liu S, Wang J
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(6):2547-2563
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(6):2547-2563
Tumor-Secreted Exosomal miR-222 Promotes Tumor Progression via Regulating P27 Expression and Re-Localization in Pancreatic Cancer.
Li Z, Tao Y, Wang X, Jiang P, Li J, Peng M, Zhang X, Chen K, Liu H, Zhen P, Zhu J, Liu X, Liu X
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(2):610-629
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(2):610-629
High Concentration of Aspirin Induces Apoptosis in Rat Tendon Stem Cells via Inhibition of the Wnt/β-Catenin Pathway.
Wang Y, Tang H, He G, Shi Y, Kang X, Lyu J, Zhou M, Zhu M, Zhang J, Tang K
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(6):2046-2059
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(6):2046-2059
Mesenchymal Stem Cell-Derived Exosomes Reduce A1 Astrocytes via Downregulation of Phosphorylated NFκB P65 Subunit in Spinal Cord Injury.
Wang L, Pei S, Han L, Guo B, Li Y, Duan R, Yao Y, Xue B, Chen X, Jia Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(4):1535-1559
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(4):1535-1559
LncRNA PCGEM1 Induces Ovarian Carcinoma Tumorigenesis and Progression Through RhoA Pathway.
Chen S, Wang LL, Sun KX, Liu Y, Guan X, Zong ZH, Zhao Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(4):1578-1588
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(4):1578-1588
The influence of GAPT extraction on synapse loss of APPswe/PS1dE9 transgenic mice via adjusting Bcl-2/Bax balance.
Shi J, Zhang X, Ni J, Wei M, Li T, Zhou B, Liu X, Zhang L, Wang P, Tian J, Wang Y
Alzheimer's & dementia (New York, N. Y.) 2018;4:724-736
Alzheimer's & dementia (New York, N. Y.) 2018;4:724-736
The Potential Protective Effect of Curcumin on Amyloid-β-42 Induced Cytotoxicity in HT-22 Cells.
Zhang L, Fang Y, Cheng X, Lian Y, Zeng Z, Wu C, Zhu H, Xu H
BioMed research international 2018;2018:8134902
BioMed research international 2018;2018:8134902
Ingredients from Litsea garrettii as Potential Preventive Agents against Oxidative Insult and Inflammatory Response.
Li YR, Li GH, Sun L, Li L, Liu Y, Kong DG, Wang SQ, Ren DM, Wang XN, Lou HX, Shen T
Oxidative medicine and cellular longevity 2018;2018:7616852
Oxidative medicine and cellular longevity 2018;2018:7616852
Serum and Ectopic Endometrium from Women with Endometriosis Modulate Macrophage M1/M2 Polarization via the Smad2/Smad3 Pathway.
Nie MF, Xie Q, Wu YH, He H, Zou LJ, She XL, Wu XQ
Journal of immunology research 2018;2018:6285813
Journal of immunology research 2018;2018:6285813
Dysfunction of Nrf2-ARE Signaling Pathway: Potential Pathogenesis in the Development of Neurocognitive Impairment in Patients with Moderate to Severe Obstructive Sleep Apnea-Hypopnea Syndrome.
Zhou L, Ouyang R, Luo H, Peng Y, Chen P, Ren S, Liu G
Oxidative medicine and cellular longevity 2018;2018:3529709
Oxidative medicine and cellular longevity 2018;2018:3529709
Fucosterol Protects against Concanavalin A-Induced Acute Liver Injury: Focus on P38 MAPK/NF-κB Pathway Activity.
Mo W, Wang C, Li J, Chen K, Xia Y, Li S, Xu L, Lu X, Wang W, Guo C
Gastroenterology research and practice 2018;2018:2824139
Gastroenterology research and practice 2018;2018:2824139
Effects of Chicory on Serum Uric Acid, Renal Function, and GLUT9 Expression in Hyperuricaemic Rats with Renal Injury and In Vitro Verification with Cells.
Jin YN, Lin ZJ, Zhang B, Bai YF
Evidence-based complementary and alternative medicine : eCAM 2018;2018:1764212
Evidence-based complementary and alternative medicine : eCAM 2018;2018:1764212
Necrostatin-1 promotes ectopic periodontal tissue like structure regeneration in LPS-treated PDLSCs.
Yan B, Zhang H, Dai T, Gu Y, Qiu X, Hu C, Liu Y, Wei K, Li D
PloS one 2018;13(11):e0207760
PloS one 2018;13(11):e0207760
Targeting MAPK Pathways by Naringenin Modulates Microglia M1/M2 Polarization in Lipopolysaccharide-Stimulated Cultures.
Zhang B, Wei YZ, Wang GQ, Li DD, Shi JS, Zhang F
Frontiers in cellular neuroscience 2018;12:531
Frontiers in cellular neuroscience 2018;12:531
Arsenic sulfide amplifies JQ1 toxicity via mitochondrial pathway in gastric and colon cancer cells.
Tan Z, Zhang X, Kang T, Zhang L, Chen S
Drug design, development and therapy 2018;12:3913-3927
Drug design, development and therapy 2018;12:3913-3927
Over-expression of prolyl isomerase Pin1 promotes cervical tumorigenesis and metastasis.
Ma JQ, Yang Y, Juan J, Guo CF, Tuerxun M, Ting W, Hasim A
International journal of clinical and experimental pathology 2018;11(2):664-674
International journal of clinical and experimental pathology 2018;11(2):664-674
Natural antisense transcript of hypoxia-inducible factor 1 regulates hypoxic cell apoptosis in epithelial ovarian cancer.
Qiu JJ, Lin XJ, Zheng TT, Tang XY, Hua KQ
OncoTargets and therapy 2018;11:9101-9110
OncoTargets and therapy 2018;11:9101-9110
Contribution of dysregulated circRNA_100876 to proliferation and metastasis of esophageal squamous cell carcinoma.
Cao S, Chen G, Yan L, Li L, Huang X
OncoTargets and therapy 2018;11:7385-7394
OncoTargets and therapy 2018;11:7385-7394
Combination Treatment of Icariin and L-DOPA Against 6-OHDA-Lesioned Dopamine Neurotoxicity.
Lu DS, Chen C, Zheng YX, Li DD, Wang GQ, Liu J, Shi J, Zhang F
Frontiers in molecular neuroscience 2018;11:155
Frontiers in molecular neuroscience 2018;11:155
Lithium chloride inhibits cell survival, overcomes drug resistance, and triggers apoptosis in multiple myeloma via activation of the Wnt/β-catenin pathway.
Yao R, Sun X, Xie Y, Liu L, Han D, Yao Y, Li H, Li Z, Xu K
American journal of translational research 2018;10(8):2610-2618
American journal of translational research 2018;10(8):2610-2618
Leucine Carboxyl Methyltransferase Downregulation and Protein Phosphatase Methylesterase Upregulation Contribute Toward the Inhibition of Protein Phosphatase 2A by α-Synuclein.
Tian H, Lu Y, Liu J, Liu W, Lu L, Duan C, Gao G, Yang H
Frontiers in aging neuroscience 2018;10:173
Frontiers in aging neuroscience 2018;10:173
Cdk5 Inhibitory Peptide Prevents Loss of Dopaminergic Neurons and Alleviates Behavioral Changes in an MPTP Induced Parkinson's Disease Mouse Model.
He R, Huang W, Huang Y, Xu M, Song P, Huang Y, Xie H, Hu Y
Frontiers in aging neuroscience 2018;10:162
Frontiers in aging neuroscience 2018;10:162
lncRNA DLEU1 contributes to tumorigenesis and development of endometrial carcinoma by targeting mTOR.
Du Y, Wang L, Chen S, Liu Y, Zhao Y
Molecular carcinogenesis 2018 Sep;57(9):1191-1200
Molecular carcinogenesis 2018 Sep;57(9):1191-1200
Curcumin attenuates resistance to irinotecan via induction of apoptosis of cancer stem cells in chemoresistant colon cancer cells.
Su P, Yang Y, Wang G, Chen X, Ju Y
International journal of oncology 2018 Sep;53(3):1343-1353
International journal of oncology 2018 Sep;53(3):1343-1353
MiR-20a-3p regulates TGF-β1/Survivin pathway to affect keratinocytes proliferation and apoptosis by targeting SFMBT1 in vitro.
Li R, Qiao M, Zhao X, Yan J, Wang X, Sun Q
Cellular signalling 2018 Sep;49:95-104
Cellular signalling 2018 Sep;49:95-104
Resveratrol relieves particulate matter (mean diameter < 2.5 μm)-induced oxidative injury of lung cells through attenuation of autophagy deregulation.
Li Y, Qian W, Wang D, Meng Y, Wang X, Chen Y, Li X, Xie C, Zhong C, Fu S
Journal of applied toxicology : JAT 2018 Sep;38(9):1251-1261
Journal of applied toxicology : JAT 2018 Sep;38(9):1251-1261
Artemisitene suppresses tumorigenesis by inducing DNA damage through deregulating c-Myc-topoisomerase pathway.
Chen J, Li W, Cui K, Ji K, Xu S, Xu Y
Oncogene 2018 Sep;37(37):5079-5087
Oncogene 2018 Sep;37(37):5079-5087
Knockdown of long noncoding RNA GHET1 inhibits cell‑cycle progression and invasion of gastric cancer cells.
Xia Y, Yan Z, Wan Y, Wei S, Bi Y, Zhao J, Liu J, Liao DJ, Huang H
Molecular medicine reports 2018 Sep;18(3):3375-3381
Molecular medicine reports 2018 Sep;18(3):3375-3381
TAM Infiltration Differences in "Tumor-First" and " ZHENG-First" Models and the Underlying Inflammatory Molecular Mechanism in Pancreatic Cancer.
Wang FJ, Wang P, Chen LY, Geng YW, Chen H, Meng ZQ, Liu LM, Chen Z
Integrative cancer therapies 2018 Sep;17(3):707-716
Integrative cancer therapies 2018 Sep;17(3):707-716
Overexpression of SMARCA2 or CAMK2D is associated with cisplatin resistance in human epithelial ovarian cancer.
Xu X, Zheng Z, Jia L, Suo S, Liu B, Shao T, Tu Q, Hua Y, Xu H
Oncology letters 2018 Sep;16(3):3796-3804
Oncology letters 2018 Sep;16(3):3796-3804
Effects of SB202190 on expression levels of IL-6 and NF-κB in flap ischemia-reperfusion injury.
Guo K, Ma J, Liang W
Experimental and therapeutic medicine 2018 Sep;16(3):2522-2526
Experimental and therapeutic medicine 2018 Sep;16(3):2522-2526
2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone, a potent Nrf2/ARE pathway inhibitor, reverses drug resistance by decreasing glutathione synthesis and drug efflux in BEL-7402/5-FU cells.
Wei X, Mo X, An F, Ji X, Lu Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2018 Sep;119:252-259
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2018 Sep;119:252-259
Bexarotene protects against neurotoxicity partially through a PPARγ-dependent mechanism in mice following traumatic brain injury.
He J, Liu H, Zhong J, Guo Z, Wu J, Zhang H, Huang Z, Jiang L, Li H, Zhang Z, Liu L, Wu Y, Qi L, Sun X, Cheng C
Neurobiology of disease 2018 Sep;117:114-124
Neurobiology of disease 2018 Sep;117:114-124
miR-383 negatively regulates osteoblastic differentiation of bone marrow mesenchymal stem cells in rats by targeting Satb2.
Tang J, Zhang Z, Jin X, Shi H
Bone 2018 Sep;114:137-143
Bone 2018 Sep;114:137-143
Oxymatrine Inhibits Transforming Growth Factor β1 (TGF-β1)-Induced Cardiac Fibroblast-to-Myofibroblast Transformation (FMT) by Mediating the Notch Signaling Pathway In Vitro.
Zhao L, Xu Y, Tao L, Yang Y, Shen X, Li L, Luo P
Medical science monitor : international medical journal of experimental and clinical research 2018 Sep 9;24:6280-6288
Medical science monitor : international medical journal of experimental and clinical research 2018 Sep 9;24:6280-6288
Lactate enhanced the effect of parathyroid hormone on osteoblast differentiation via GPR81-PKC-Akt signaling.
Wu Y, Wang M, Zhang K, Li Y, Xu M, Tang S, Qu X, Li C
Biochemical and biophysical research communications 2018 Sep 5;503(2):737-743
Biochemical and biophysical research communications 2018 Sep 5;503(2):737-743
H2A.Z.1 crosstalk with H3K56-acetylation controls gliogenesis through the transcription of folate receptor.
Su L, Xia W, Shen T, Liang Q, Wang W, Li H, Jiao J
Nucleic acids research 2018 Sep 28;46(17):8817-8831
Nucleic acids research 2018 Sep 28;46(17):8817-8831
RING finger protein 10 prevents neointimal hyperplasia by promoting apoptosis in vitro and in vivo.
Yu G, Chen J, Li S, Pu P, Huang W, Zhao Y, Peng X, Wang R, Lei H
Life sciences 2018 Sep 1;208:325-332
Life sciences 2018 Sep 1;208:325-332
miR‑92b promotes autophagy and suppresses viability and invasion in breast cancer by targeting EZH2.
Liu F, Sang M, Meng L, Gu L, Liu S, Li J, Geng C
International journal of oncology 2018 Oct;53(4):1505-1515
International journal of oncology 2018 Oct;53(4):1505-1515
Acrolein-induced autophagy-dependent apoptosis via activation of the lysosomal-mitochondrial pathway in EAhy926 cells.
Luo S, Jiang L, Li Q, Sun X, Liu T, Pei F, Zhang T, Liu T, Dong L, Liu X, Jiang L
Toxicology in vitro : an international journal published in association with BIBRA 2018 Oct;52:146-153
Toxicology in vitro : an international journal published in association with BIBRA 2018 Oct;52:146-153
Erythropoietin Treatment Ameliorates Lupus Nephritis of MRL/lpr Mice.
Zhang Z, Liu D, Zhang X, Wang X
Inflammation 2018 Oct;41(5):1888-1899
Inflammation 2018 Oct;41(5):1888-1899
lncRNA GAS5 inhibits colorectal cancer cell proliferation via the miR‑182‑5p/FOXO3a axis.
Cheng K, Zhao Z, Wang G, Wang J, Zhu W
Oncology reports 2018 Oct;40(4):2371-2380
Oncology reports 2018 Oct;40(4):2371-2380
MicroRNA‑106a regulates the proliferation and invasion of human osteosarcoma cells by targeting VNN2.
Chen Y, Huang T, Yang X, Liu C, Li P, Wang Z, Zhi S
Oncology reports 2018 Oct;40(4):2251-2259
Oncology reports 2018 Oct;40(4):2251-2259
Association between Tim‑3 and Gal‑9 expression and gastric cancer prognosis.
Wang Y, Zhao E, Zhang Z, Zhao G, Cao H
Oncology reports 2018 Oct;40(4):2115-2126
Oncology reports 2018 Oct;40(4):2115-2126
Low-Dose Radiation Enhanced Inhibition of Breast Tumor Xenograft and Reduced Myocardial Injury Induced by Doxorubicin.
Jiang X, Du Y, Meng X, Zhang H, Zhao D, Zhao L, Chen J, Xiao S, Jiang H
Dose-response : a publication of International Hormesis Society 2018 Oct-Dec;16(4):1559325818813061
Dose-response : a publication of International Hormesis Society 2018 Oct-Dec;16(4):1559325818813061
High expression of WNT7A predicts poor prognosis and promote tumor metastasis in pancreatic ductal adenocarcinoma.
Wu DJ, Jiang YS, He RZ, Tao LY, Yang MW, Fu XL, Yang JY, Zhu K
Scientific reports 2018 Oct 25;8(1):15792
Scientific reports 2018 Oct 25;8(1):15792
Construction of a High-Efficiency Drug and Gene Co-Delivery System for Cancer Therapy from a pH-Sensitive Supramolecular Inclusion between Oligoethylenimine- graft-β-cyclodextrin and Hyperbranched Polyglycerol Derivative.
Zhou X, Xu L, Xu J, Wu J, Kirk TB, Ma D, Xue W
ACS applied materials & interfaces 2018 Oct 24;10(42):35812-35829
ACS applied materials & interfaces 2018 Oct 24;10(42):35812-35829
ERα is a negative regulator of PD-L1 gene transcription in breast cancer.
Liu L, Shen Y, Zhu X, Lv R, Li S, Zhang Z, Shi YG, Tan L
Biochemical and biophysical research communications 2018 Oct 20;505(1):157-161
Biochemical and biophysical research communications 2018 Oct 20;505(1):157-161
Temozolomide-Perillyl alcohol conjugate impairs Mitophagy flux by inducing lysosomal dysfunction in non-small cell lung Cancer cells and sensitizes them to irradiation.
Chang M, Song X, Geng X, Wang X, Wang W, Chen TC, Xie L, Song X
Journal of experimental & clinical cancer research : CR 2018 Oct 16;37(1):250
Journal of experimental & clinical cancer research : CR 2018 Oct 16;37(1):250
CNTNAP4 Impacts Epilepsy Through GABAA Receptors Regulation: Evidence From Temporal Lobe Epilepsy Patients and Mouse Models.
Shangguan Y, Xu X, Ganbat B, Li Y, Wang W, Yang Y, Lu X, Du C, Tian X, Wang X
Cerebral cortex (New York, N.Y. : 1991) 2018 Oct 1;28(10):3491-3504
Cerebral cortex (New York, N.Y. : 1991) 2018 Oct 1;28(10):3491-3504
Cold-induced protein RBM3 orchestrates neurogenesis via modulating Yap mRNA stability in cold stress.
Xia W, Su L, Jiao J
The Journal of cell biology 2018 Oct 1;217(10):3464-3479
The Journal of cell biology 2018 Oct 1;217(10):3464-3479
BF211, a derivative of bufalin, enhances the cytocidal effects in multiple myeloma cells by inhibiting the IL-6/JAK2/STAT3 pathway.
Wu XY, Tian F, Su MH, Wu M, Huang Y, Hu LH, Jin L, Zhu XJ
International immunopharmacology 2018 Nov;64:24-32
International immunopharmacology 2018 Nov;64:24-32
Biological functions and clinical significance of the newly identified long non‑coding RNA RP1‑85F18.6 in colorectal cancer.
Ma Y, Chen Y, Lin C, Hu G
Oncology reports 2018 Nov;40(5):2648-2658
Oncology reports 2018 Nov;40(5):2648-2658
FGF9 modulates Schwann cell myelination in developing nerves and induces a pro-inflammatory environment during injury.
Deng B, Lv W, Duan W, Liu Y, Li Z, Song X, Cui C, Qi X, Wang X, Li C
Journal of cellular biochemistry 2018 Nov;119(10):8643-8658
Journal of cellular biochemistry 2018 Nov;119(10):8643-8658
Pyroptosis of HUVECs can be induced by heat stroke.
Pei Y, Geng Y, Su L
Biochemical and biophysical research communications 2018 Nov 30;506(3):626-631
Biochemical and biophysical research communications 2018 Nov 30;506(3):626-631
An E-selectin targeting and MMP-2-responsive dextran-curcumin polymeric prodrug for targeted therapy of acute kidney injury.
Hu JB, Liu D, Qi J, Lu KJ, Jin FY, Ying XY, You J, Du YZ
Biomaterials science 2018 Nov 20;6(12):3397-3409
Biomaterials science 2018 Nov 20;6(12):3397-3409
Polybrominated Diphenyl Ethers Quinone Induced Parthanatos-like Cell Death through a Reactive Oxygen Species-Associated Poly(ADP-ribose) Polymerase 1 Signaling.
Dong W, Yang B, Wang Y, Yuan J, Fan Y, Song E, Song Y
Chemical research in toxicology 2018 Nov 19;31(11):1164-1171
Chemical research in toxicology 2018 Nov 19;31(11):1164-1171
Luteolin sensitizes the antitumor effect of cisplatin in drug-resistant ovarian cancer via induction of apoptosis and inhibition of cell migration and invasion.
Wang H, Luo Y, Qiao T, Wu Z, Huang Z
Journal of ovarian research 2018 Nov 19;11(1):93
Journal of ovarian research 2018 Nov 19;11(1):93
Retraction: Cd induces G2/M cell cycle arrest by up-regulating miR-133b via directly targeting PPP2R2D in L02 hepatocytes.
Zhang Y, Xiao F, Zhong C, Zeng M, Zou L
Metallomics : integrated biometal science 2018 Nov 14;10(11):1701
Metallomics : integrated biometal science 2018 Nov 14;10(11):1701
Lysyl oxidase blockade ameliorates anovulation in polycystic ovary syndrome.
Zhang C, Ma J, Wang W, Sun Y, Sun K
Human reproduction (Oxford, England) 2018 Nov 1;33(11):2096-2106
Human reproduction (Oxford, England) 2018 Nov 1;33(11):2096-2106
Decrease of galectin-3 in keratinocytes: A potential diagnostic marker and a critical contributor to the pathogenesis of psoriasis.
Shi ZR, Tan GZ, Cao CX, Han YF, Meng Z, Man XY, Jiang ZX, Zhang YP, Dang NN, Wei KH, Bu DF, Liu FT, Wang L
Journal of autoimmunity 2018 May;89:30-40
Journal of autoimmunity 2018 May;89:30-40
The inhibitory effect in Fraxinellone on oxidative stress-induced senescence correlates with AMP-activated protein kinase-dependent autophagy restoration.
Han X, Chen H, Zhou J, Tai H, Gong H, Wang X, Huang N, Qin J, Fang T, Wang F, Xiao H
Journal of cellular physiology 2018 May;233(5):3945-3954
Journal of cellular physiology 2018 May;233(5):3945-3954
PD-L1 confers glioblastoma multiforme malignancy via Ras binding and Ras/Erk/EMT activation.
Qiu XY, Hu DX, Chen WQ, Chen RQ, Qian SR, Li CY, Li YJ, Xiong XX, Liu D, Pan F, Yu SB, Chen XQ
Biochimica et biophysica acta. Molecular basis of disease 2018 May;1864(5 Pt A):1754-1769
Biochimica et biophysica acta. Molecular basis of disease 2018 May;1864(5 Pt A):1754-1769
Reversing Multidrug Resistance by Multiplexed Gene Silencing for Enhanced Breast Cancer Chemotherapy.
Li Y, Gao X, Yu Z, Liu B, Pan W, Li N, Tang B
ACS applied materials & interfaces 2018 May 9;10(18):15461-15466
ACS applied materials & interfaces 2018 May 9;10(18):15461-15466
Interfering RNA against PKC-α inhibits TNF-α-induced IP(3)R1 expression and improves glomerular filtration rate in rats with fulminant hepatic failure.
Wang DL, Dai WY, Wang W, Wen Y, Zhou Y, Zhao YT, Wu J, Liu P
American journal of physiology. Renal physiology 2018 May 1;314(5):F942-F955
American journal of physiology. Renal physiology 2018 May 1;314(5):F942-F955
Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.
Jia YN, Lu HP, Peng YL, Zhang BS, Gong XB, Su J, Zhou Y, Pan MH, Xu L
International immunopharmacology 2018 Mar;56:105-112
International immunopharmacology 2018 Mar;56:105-112
Donor Treatment With a Hypoxia-Inducible Factor-1 Agonist Prevents Donation After Cardiac Death Liver Graft Injury in a Rat Isolated Perfusion Model.
Zhang X, Liu Z, Xiao Q, Zeng C, Lai CH, Fan X, Ye Q, Wang Y, Xiong Y
Artificial organs 2018 Mar;42(3):280-289
Artificial organs 2018 Mar;42(3):280-289
Proteomics analysis of altered proteins in kidney of mice with aristolochic acid nephropathy using the fluorogenic derivatization-liquid chromatography-tandem mass spectrometry method.
Lin CE, Chang WS, Lee JA, Chang TY, Huang YS, Hirasaki Y, Chen HS, Imai K, Chen SM
Biomedical chromatography : BMC 2018 Mar;32(3)
Biomedical chromatography : BMC 2018 Mar;32(3)
Expression of diaphragmatic myostatin and correlation with apoptosis in rats with chronic obstructive pulmonary disease.
Zhou X, Yi D, Wu Y, Pei X, Yu H, Chen Y, Jiang Y, Li W
Experimental and therapeutic medicine 2018 Mar;15(3):2295-2300
Experimental and therapeutic medicine 2018 Mar;15(3):2295-2300
Lipoxin A4 improves erectile dysfunction in rats with type I diabetes by inhibiting oxidative stress and corporal fibrosis.
Cui K, Tang Z, Li CC, Wang T, Rao K, Wang SG, Liu JH, Chen Z
Asian journal of andrology 2018 Mar-Apr;20(2):166-172
Asian journal of andrology 2018 Mar-Apr;20(2):166-172
Marine Bacterial Polysaccharide EPS11 Inhibits Cancer Cell Growth via Blocking Cell Adhesion and Stimulating Anoikis.
Cao R, Jin W, Shan Y, Wang J, Liu G, Kuang S, Sun C
Marine drugs 2018 Mar 8;16(3)
Marine drugs 2018 Mar 8;16(3)
AMPK alleviates endoplasmic reticulum stress by inducing the ER-chaperone ORP150 via FOXO1 to protect human bronchial cells from apoptosis.
Liu JQ, Zhang L, Yao J, Yao S, Yuan T
Biochemical and biophysical research communications 2018 Mar 4;497(2):564-570
Biochemical and biophysical research communications 2018 Mar 4;497(2):564-570
7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway.
Tsai TC, Lai KH, Su JH, Wu YJ, Sheu JH
Marine drugs 2018 Mar 26;16(4)
Marine drugs 2018 Mar 26;16(4)
In vitro inhibition of porcine reproductive and respiratory syndrome virus replication by short antisense oligonucleotides with locked nucleic acid modification.
Zhu L, Bi J, Zheng L, Zhao Q, Shu X, Guo G, Liu J, Yang G, Liu J, Yin G
BMC veterinary research 2018 Mar 26;14(1):109
BMC veterinary research 2018 Mar 26;14(1):109
Epidermal Growth Factor, through Alleviating Oxidative Stress, Protect IPEC-J2 Cells from Lipopolysaccharides-Induced Apoptosis.
Tang X, Liu B, Wang X, Yu Q, Fang R
International journal of molecular sciences 2018 Mar 14;19(3)
International journal of molecular sciences 2018 Mar 14;19(3)
Early Postnatal Exposure to Airborne Fine Particulate Matter Induces Autism-like Phenotypes in Male Rats.
Li K, Li L, Cui B, Gai Z, Li Q, Wang S, Yan J, Lin B, Tian L, Liu H, Liu X, Xi Z
Toxicological sciences : an official journal of the Society of Toxicology 2018 Mar 1;162(1):189-199
Toxicological sciences : an official journal of the Society of Toxicology 2018 Mar 1;162(1):189-199
All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway.
Li M, Tian X, An R, Yang M, Zhang Q, Xiang F, Liu H, Wang Y, Xu L, Dong Z
Neurochemical research 2018 Jun;43(6):1283-1296
Neurochemical research 2018 Jun;43(6):1283-1296
Formononetin inhibits colon carcinoma cell growth and invasion by microRNA‑149‑mediated EphB3 downregulation and inhibition of PI3K/AKT and STAT3 signaling pathways.
Wang AL, Li Y, Zhao Q, Fan LQ
Molecular medicine reports 2018 Jun;17(6):7721-7729
Molecular medicine reports 2018 Jun;17(6):7721-7729
Expression of tumor suppressor programmed cell death 4 in endometrioid endometrial carcinomas and clinicopathological significance.
Liu Y, Sun H, Mao H, Gao M, Tan X, Li Y, Li Y, Muloye GM, Zhang L, Wang X, Wei Z
Oncology letters 2018 Jun;15(6):9369-9376
Oncology letters 2018 Jun;15(6):9369-9376
FPOA induces apoptosis in HeLa human cervical cancer cells through a caspase-mediated pathway.
Li X, Bau T, Bao H
Oncology letters 2018 Jun;15(6):8357-8362
Oncology letters 2018 Jun;15(6):8357-8362
Pseudo-Ginsenoside Rh2 induces A549 cells apoptosis via the Ras/Raf/ERK/p53 pathway.
Wang Y, Xu H, Lu Z, Yu X, Lv C, Tian Y, Sui D
Experimental and therapeutic medicine 2018 Jun;15(6):4916-4924
Experimental and therapeutic medicine 2018 Jun;15(6):4916-4924
Effects of Tumor Necrosis Factor α (TNF-α) and Interleukina 10 (IL-10) on Intercellular Cell Adhesion Molecule-1 (ICAM-1) and Cluster of Differentiation 31 (CD31) in Human Coronary Artery Endothelial Cells.
Xue M, Qiqige C, Zhang Q, Zhao H, Su L, Sun P, Zhao P
Medical science monitor : international medical journal of experimental and clinical research 2018 Jun 27;24:4433-4439
Medical science monitor : international medical journal of experimental and clinical research 2018 Jun 27;24:4433-4439
Chronic cold exposure results in subcutaneous adipose tissue browning and altered global metabolism in Qinghai-Tibetan plateau pika (Ochotona curzoniae).
Li J, Yang Q, Bai Z, Zhou W, Semenza GL, Ge RL
Biochemical and biophysical research communications 2018 Jun 2;500(2):117-123
Biochemical and biophysical research communications 2018 Jun 2;500(2):117-123
Regional up-regulation of NOX2 contributes to the differential vulnerability of outer hair cells to neomycin.
Qi M, Qiu Y, Zhou X, Tian K, Zhou K, Sun F, Yue B, Chen F, Zha D, Qiu J
Biochemical and biophysical research communications 2018 Jun 2;500(2):110-116
Biochemical and biophysical research communications 2018 Jun 2;500(2):110-116
Atrazine exposure improves the proliferation of H22 cells in vitro and in vivo.
Tian Y, He J, Liu N, Huang D, Liu Z, Yang Y, Chen J, Zhao B, Zhao S, Liang B
RSC advances 2018 Jun 13;8(39):21759-21767
RSC advances 2018 Jun 13;8(39):21759-21767
Down-regulation of IFIT3 protects liver from ischemia-reperfusion injury.
Guan G, Shen Y, Yu Q, Liu H, Zhang B, Guo Y, Zhu X, Li Z, Rao W, Zhuang L, Zang Y
International immunopharmacology 2018 Jul;60:170-178
International immunopharmacology 2018 Jul;60:170-178
Long non-coding RNA (lncRNA) MAGI2-AS3 inhibits breast cancer cell growth by targeting the Fas/FasL signalling pathway.
Yang Y, Yang H, Xu M, Zhang H, Sun M, Mu P, Dong T, Du S, Liu K
Human cell 2018 Jul;31(3):232-241
Human cell 2018 Jul;31(3):232-241
Wnt/β-catenin modulates chronic tobacco smoke exposure-induced acquisition of pulmonary cancer stem cell properties and diallyl trisulfide intervention.
Wang J, Chen J, Jiang Y, Shi Y, Zhu J, Xie C, Geng S, Wu J, Zhang Q, Wang X, Meng Y, Li Y, Chen Y, Cao W, Wang X, Zhong C, Li X
Toxicology letters 2018 Jul;291:70-76
Toxicology letters 2018 Jul;291:70-76
A Polysaccharide Isolated from Dictyophora indusiata Promotes Recovery from Antibiotic-Driven Intestinal Dysbiosis and Improves Gut Epithelial Barrier Function in a Mouse Model.
Kanwal S, Joseph TP, Owusu L, Xiaomeng R, Meiqi L, Yi X
Nutrients 2018 Jul 31;10(8)
Nutrients 2018 Jul 31;10(8)
Glutathione Reduction of Patulin-Evoked Cytotoxicity in HEK293 Cells by the Prevention of Oxidative Damage and the Mitochondrial Apoptotic Pathway.
Wang X, Jin C, Zhong Y, Li X, Han J, Xue W, Wu P, Xia X, Peng X
Journal of agricultural and food chemistry 2018 Jul 25;66(29):7775-7785
Journal of agricultural and food chemistry 2018 Jul 25;66(29):7775-7785
Intermittent streptozotocin administration induces behavioral and pathological features relevant to Alzheimer's disease and vascular dementia.
Murtishaw AS, Heaney CF, Bolton MM, Belmonte KCD, Langhardt MA, Kinney JW
Neuropharmacology 2018 Jul 15;137:164-177
Neuropharmacology 2018 Jul 15;137:164-177
Baicalein inhibits cervical cancer progression via downregulating long noncoding RNA BDLNR and its downstream PI3K/Akt pathway.
Yu X, Yang Y, Li Y, Cao Y, Tang L, Chen F, Xia J
The international journal of biochemistry & cell biology 2018 Jan;94:107-118
The international journal of biochemistry & cell biology 2018 Jan;94:107-118
Activation of Nrf2 pathway and inhibition of NLRP3 inflammasome activation contribute to the protective effect of chlorogenic acid on acute liver injury.
Shi A, Shi H, Wang Y, Liu X, Cheng Y, Li H, Zhao H, Wang S, Dong L
International immunopharmacology 2018 Jan;54:125-130
International immunopharmacology 2018 Jan;54:125-130
Nitric oxide, afferent sensory nerves, and antioxidative enzymes in the mechanism of protection mediated by tricarbonyldichlororuthenium(II) dimer and sodium hydrosulfide against aspirin-induced gastric damage.
Magierowski M, Hubalewska-Mazgaj M, Magierowska K, Wojcik D, Sliwowski Z, Kwiecien S, Brzozowski T
Journal of gastroenterology 2018 Jan;53(1):52-63
Journal of gastroenterology 2018 Jan;53(1):52-63
Inhibition of Rho kinase protects against colitis in mice by attenuating intestinal epithelial barrier dysfunction via MLC and the NF-κB pathway.
Zou Y, Ma L, Zhao Y, Zhang S, Zhou C, Cai Y
International journal of molecular medicine 2018 Jan;41(1):430-438
International journal of molecular medicine 2018 Jan;41(1):430-438
Anticancer effect of SZC015 on pancreatic cancer via mitochondria-dependent apoptosis and the constitutive suppression of activated nuclear factor κB and STAT3 in vitro and in vivo.
Song Y, Gao L, Tang Z, Li H, Sun B, Chu P, Qaed E, Ma X, Peng J, Wang S, Hu M, Tang Z
Journal of cellular physiology 2018 Jan;234(1):777-788
Journal of cellular physiology 2018 Jan;234(1):777-788
Thrombopoietin protects H9C2 cells from excessive autophagy and apoptosis in doxorubicin-induced cardiotoxicity.
Wang H, Wang H, Liang EY, Zhou LX, Dong ZL, Liang P, Weng QF, Yang M
Oncology letters 2018 Jan;15(1):839-848
Oncology letters 2018 Jan;15(1):839-848
Exogenous oxidants activate nuclear factor kappa B through Toll-like receptor 4 stimulation to maintain inflammatory phenotype in macrophage.
Zhang Y, Igwe OJ
Biochemical pharmacology 2018 Jan;147:104-118
Biochemical pharmacology 2018 Jan;147:104-118
Experimental evidence of good efficacy and reduced toxicity with peptide-doxorubicin to treat gastric cancer.
Zhang J, Yuan JP, Wang Q, Shao LH, Liu SP, Firestone RA, Hong YP, Li JG, Xin YC, Li Y
Oncotarget 2018 Jan 5;9(2):1957-1968
Oncotarget 2018 Jan 5;9(2):1957-1968
The protective role of low-concentration alcohol in high-fructose induced adverse cardiovascular events in mice.
Wu X, Pan B, Wang Y, Liu L, Huang X, Tian J
Biochemical and biophysical research communications 2018 Jan 1;495(1):1403-1410
Biochemical and biophysical research communications 2018 Jan 1;495(1):1403-1410
Nicotine Induces Progressive Properties of Lung Adenocarcinoma A549 Cells by Inhibiting Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Expression and Plasma Membrane Localization.
Li H, Ma N, Wang J, Wang Y, Yuan C, Wu J, Luo M, Yang J, Chen J, Shi J, Liu X
Technology in cancer research & treatment 2018 Jan 1;17:1533033818809984
Technology in cancer research & treatment 2018 Jan 1;17:1533033818809984
Effects of calycosin against high-fat diet-induced nonalcoholic fatty liver disease in mice.
Duan X, Meng Q, Wang C, Liu Z, Sun H, Huo X, Sun P, Ma X, Peng J, Liu K
Journal of gastroenterology and hepatology 2018 Feb;33(2):533-542
Journal of gastroenterology and hepatology 2018 Feb;33(2):533-542
Genipin alleviates high-fat diet-induced hyperlipidemia and hepatic lipid accumulation in mice via miR-142a-5p/SREBP-1c axis.
Zhong H, Chen K, Feng M, Shao W, Wu J, Chen K, Liang T, Liu C
The FEBS journal 2018 Feb;285(3):501-517
The FEBS journal 2018 Feb;285(3):501-517
Di-(2-ethylhexyl)-phthalate induces glucose metabolic disorder in adolescent rats.
Xu J, Zhou L, Wang S, Zhu J, Liu T, Jia Y, Sun D, Chen H, Wang Q, Xu F, Zhang Y, Liu H, Zhang T, Ye L
Environmental science and pollution research international 2018 Feb;25(4):3596-3607
Environmental science and pollution research international 2018 Feb;25(4):3596-3607
RNF20 controls astrocytic differentiation through epigenetic regulation of STAT3 in the developing brain.
Liang Q, Xia W, Li W, Jiao J
Cell death and differentiation 2018 Feb;25(2):294-306
Cell death and differentiation 2018 Feb;25(2):294-306
Construction and protective immunogenicity of DNA vaccine pNMB0315 against Neisseria meningitidis serogroup B.
Wu X, Li K, Xie M, Yu M, Tang S, Li Z, Hu S
Molecular medicine reports 2018 Feb;17(2):3178-3185
Molecular medicine reports 2018 Feb;17(2):3178-3185
The N-terminal ubiquitin-associated domain of Cezanne is crucial for its function to suppress NF-κB pathway.
Ji Y, Cao L, Zeng L, Zhang Z, Xiao Q, Guan P, Chen S, Chen Y, Wang M, Guo D
Journal of cellular biochemistry 2018 Feb;119(2):1979-1991
Journal of cellular biochemistry 2018 Feb;119(2):1979-1991
miR-429 suppresses tumor migration and invasion by targeting CRKL in hepatocellular carcinoma via inhibiting Raf/MEK/ERK pathway and epithelial-mesenchymal transition.
Guo C, Zhao D, Zhang Q, Liu S, Sun MZ
Scientific reports 2018 Feb 5;8(1):2375
Scientific reports 2018 Feb 5;8(1):2375
Synergistic neuroprotective effect of rasagiline and idebenone against retinal ischemia-reperfusion injury via the Lin28-let-7-Dicer pathway.
Lei D, Shao Z, Zhou X, Yuan H
Oncotarget 2018 Feb 23;9(15):12137-12153
Oncotarget 2018 Feb 23;9(15):12137-12153
Collagen-based three-dimensional culture microenvironment promotes epithelial to mesenchymal transition and drug resistance of human ovarian cancer in vitro.
Liu M, Zhang X, Long C, Xu H, Cheng X, Chang J, Zhang C, Zhang C, Wang X
RSC advances 2018 Feb 23;8(16):8910-8919
RSC advances 2018 Feb 23;8(16):8910-8919
[Impact of Cystic Fibrosis Transmembrane Conductance Regulator on Malignant Properties of KRAS Mutant Lung Adenocarcinoma A549 Cells].
Li H, Wang Y, Yang J, Liu X, Shi J
Zhongguo fei ai za zhi = Chinese journal of lung cancer 2018 Feb 20;21(2):89-98
Zhongguo fei ai za zhi = Chinese journal of lung cancer 2018 Feb 20;21(2):89-98
RACK1 is indispensable for porcine reproductive and respiratory syndrome virus replication and NF-κB activation in Marc-145 cells.
Bi J, Zhao Q, Zhu L, Li X, Yang G, Liu J, Yin G
Scientific reports 2018 Feb 14;8(1):2985
Scientific reports 2018 Feb 14;8(1):2985
Neuroprotective Effect of Anethole Against Neuropathic Pain Induced by Chronic Constriction Injury of the Sciatic Nerve in Mice.
Wang B, Zhang G, Yang M, Liu N, Li YX, Ma H, Ma L, Sun T, Tan H, Yu J
Neurochemical research 2018 Dec;43(12):2404-2422
Neurochemical research 2018 Dec;43(12):2404-2422
Relationship of Epidermal Growth Factor Receptor Expression with Clinical Symptoms and Metastasis of Invasive Breast Cancer.
Han L, Li L, Wang N, Xiong Y, Li Y, Gu Y
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2018 Dec;38(12):578-582
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2018 Dec;38(12):578-582
Role of Long Noncoding RNA 799 in the Metastasis of Cervical Cancer through Upregulation of TBL1XR1 Expression.
Liao LM, Zhang FH, Yao GJ, Ai SF, Zheng M, Huang L
Molecular therapy. Nucleic acids 2018 Dec 7;13:580-589
Molecular therapy. Nucleic acids 2018 Dec 7;13:580-589
WISP1 mediates lung injury following hepatic ischemia reperfusion dependent on TLR4 in mice.
Tong Y, Yu Z, Zhang R, Ding X, Chen Z, Li Q
BMC pulmonary medicine 2018 Dec 6;18(1):189
BMC pulmonary medicine 2018 Dec 6;18(1):189
The Traditional Chinese Medicine MLC901 inhibits inflammation processes after focal cerebral ischemia.
Widmann C, Gandin C, Petit-Paitel A, Lazdunski M, Heurteaux C
Scientific reports 2018 Dec 24;8(1):18062
Scientific reports 2018 Dec 24;8(1):18062
Cancer-derived exosomal miR-25-3p promotes pre-metastatic niche formation by inducing vascular permeability and angiogenesis.
Zeng Z, Li Y, Pan Y, Lan X, Song F, Sun J, Zhou K, Liu X, Ren X, Wang F, Hu J, Zhu X, Yang W, Liao W, Li G, Ding Y, Liang L
Nature communications 2018 Dec 19;9(1):5395
Nature communications 2018 Dec 19;9(1):5395
Crotonols A and B, two rare tigliane diterpenoid derivatives against K562 cells from Croton tiglium.
Wang J, Qin L, Zhao B, Cai L, Zhong Z, Liu Y, Zhou X
Organic & biomolecular chemistry 2018 Dec 19;17(1):195-202
Organic & biomolecular chemistry 2018 Dec 19;17(1):195-202
Metformin suppresses growth and adrenocorticotrophic hormone secretion in mouse pituitary corticotroph tumor AtT20 cells.
Jin K, Ruan L, Pu J, Zhong A, Wang F, Tan S, Huang H, Mu J, Yang G
Molecular and cellular endocrinology 2018 Dec 15;478:53-61
Molecular and cellular endocrinology 2018 Dec 15;478:53-61
Lactobacillus helveticus KLDS1.8701 alleviates d-galactose-induced aging by regulating Nrf-2 and gut microbiota in mice.
Li B, Evivie SE, Lu J, Jiao Y, Wang C, Li Z, Liu F, Huo G
Food & function 2018 Dec 13;9(12):6586-6598
Food & function 2018 Dec 13;9(12):6586-6598
Whole-exome sequencing revealed HKDC1 as a candidate gene associated with autosomal-recessive retinitis pigmentosa.
Zhang L, Sun Z, Zhao P, Huang L, Xu M, Yang Y, Chen X, Lu F, Zhang X, Wang H, Zhang S, Liu W, Jiang Z, Ma S, Chen R, Zhao C, Yang Z, Sui R, Zhu X
Human molecular genetics 2018 Dec 1;27(23):4157-4168
Human molecular genetics 2018 Dec 1;27(23):4157-4168
Transcription Factor FOXO3a Is a Negative Regulator of Cytotoxicity of Fusarium mycotoxin in GES-1 Cells.
Yang Y, Yu S, Liu N, Xu H, Gong Y, Wu Y, Wang P, Su X, Liao Y, De Saeger S, Humpf HU, Wu A
Toxicological sciences : an official journal of the Society of Toxicology 2018 Dec 1;166(2):370-381
Toxicological sciences : an official journal of the Society of Toxicology 2018 Dec 1;166(2):370-381
Protective effects of ginsenoside Rg1 against lipopolysaccharide/d-galactosamine-induced acute liver injury in mice through inhibiting toll-like receptor 4 signaling pathway.
Ning C, Gao X, Wang C, Huo X, Liu Z, Sun H, Yang X, Sun P, Ma X, Meng Q, Liu K
International immunopharmacology 2018 Aug;61:266-276
International immunopharmacology 2018 Aug;61:266-276
Dietary eicosapentaenoic acid normalizes hippocampal omega-3 and 6 polyunsaturated fatty acid profile, attenuates glial activation and regulates BDNF function in a rodent model of neuroinflammation induced by central interleukin-1β administration.
Dong Y, Xu M, Kalueff AV, Song C
European journal of nutrition 2018 Aug;57(5):1781-1791
European journal of nutrition 2018 Aug;57(5):1781-1791
TRPC1/3/6 inhibition attenuates the TGF-β1-induced epithelial-mesenchymal transition in gastric cancer via the Ras/Raf1/ERK signaling pathway.
Ge P, Wei L, Zhang M, Hu B, Wang K, Li Y, Liu S, Wang J, Li Y
Cell biology international 2018 Aug;42(8):975-984
Cell biology international 2018 Aug;42(8):975-984
Knockdown of TIPE2 increases the proliferation in lipopolysaccharide-stimulated gastric cancer cells.
Liu W, Fan Y, Shi Y, Lin Z, Huang X, Huang W, Shen D, Qi Z
BMC cancer 2018 Aug 29;18(1):857
BMC cancer 2018 Aug 29;18(1):857
Phosphoglycerate Mutase 1 (PGAM1) Promotes Pancreatic Ductal Adenocarcinoma (PDAC) Metastasis by Acting as a Novel Downstream Target of the PI3K/Akt/mTOR Pathway.
Liu X, Tan X, Liu P, Wu Y, Qian S, Zhang X
Oncology research 2018 Aug 23;26(7):1123-1131
Oncology research 2018 Aug 23;26(7):1123-1131
Anti-inflammatory activities and potential mechanisms of phenolic acids isolated from Salvia miltiorrhiza f. alba roots in THP-1 macrophages.
Liu H, Ma S, Xia H, Lou H, Zhu F, Sun L
Journal of ethnopharmacology 2018 Aug 10;222:201-207
Journal of ethnopharmacology 2018 Aug 10;222:201-207
Hepatic, Metabolic, and Toxicity Evaluation of Repeated Oral Administration of SnS2 Nanoflowers in Mice.
Bai D, Li Q, Xiong Y, Wang C, Shen P, Bai L, Yuan L, Wu P
Toxicological sciences : an official journal of the Society of Toxicology 2018 Aug 1;164(2):501-511
Toxicological sciences : an official journal of the Society of Toxicology 2018 Aug 1;164(2):501-511
Uncoupling protein 1 expression in adipocytes derived from skeletal muscle fibro/adipogenic progenitors is under genetic and hormonal control.
Gorski T, Mathes S, Krützfeldt J
Journal of cachexia, sarcopenia and muscle 2018 Apr;9(2):384-399
Journal of cachexia, sarcopenia and muscle 2018 Apr;9(2):384-399
Aspm knockout ferret reveals an evolutionary mechanism governing cerebral cortical size.
Johnson MB, Sun X, Kodani A, Borges-Monroy R, Girskis KM, Ryu SC, Wang PP, Patel K, Gonzalez DM, Woo YM, Yan Z, Liang B, Smith RS, Chatterjee M, Coman D, Papademetris X, Staib LH, Hyder F, Mandeville JB, Grant PE, Im K, Kwak H, Engelhardt JF, Walsh CA, Bae BI
Nature 2018 Apr;556(7701):370-375
Nature 2018 Apr;556(7701):370-375
CHOP induces apoptosis by affecting brain iron metabolism in rats with subarachnoid hemorrhage.
Zhao J, Xiang X, Zhang H, Jiang D, Liang Y, Qing W, Liu L, Zhao Q, He Z
Experimental neurology 2018 Apr;302:22-33
Experimental neurology 2018 Apr;302:22-33
LPS‑induced proinflammatory cytokine expression in human airway epithelial cells and macrophages via NF‑κB, STAT3 or AP‑1 activation.
Liu X, Yin S, Chen Y, Wu Y, Zheng W, Dong H, Bai Y, Qin Y, Li J, Feng S, Zhao P
Molecular medicine reports 2018 Apr;17(4):5484-5491
Molecular medicine reports 2018 Apr;17(4):5484-5491
Regulation on SIRT1-PGC-1α/Nrf2 pathway together with selective inhibition of aldose reductase makes compound hr5F a potential agent for the treatment of diabetic complications.
Wang Z, Yuan S, Li Y, Zhang Z, Xiao W, Tang D, Ye K, Liu Z, Wang C, Zheng Y, Nie H, Chen H
Biochemical pharmacology 2018 Apr;150:54-63
Biochemical pharmacology 2018 Apr;150:54-63
Cationic nanomicelles derived from Pluronic F127 as delivery vehicles of Chinese herbal medicine active components of ursolic acid for colorectal cancer treatment.
Yan Z, Wang Q, Liu X, Peng J, Li Q, Wu M, Lin J
RSC advances 2018 Apr 27;8(29):15906-15914
RSC advances 2018 Apr 27;8(29):15906-15914
DL-3-n-butylphthalide alleviates vascular cognitive impairment induced by chronic cerebral hypoperfusion by activating the Akt/Nrf2 signaling pathway in the hippocampus of rats.
Qi Q, Xu J, Lv P, Dong Y, Liu Z, Hu M, Xiao Y, Jia Y, Jin W, Fan M, Zhang D, Meng N
Neuroscience letters 2018 Apr 13;672:59-64
Neuroscience letters 2018 Apr 13;672:59-64
Novel decellularized liver matrix-alginate hybrid gel beads for the 3D culture of hepatocellular carcinoma cells.
Sun D, Liu Y, Wang H, Deng F, Zhang Y, Zhao S, Ma X, Wu H, Sun G
International journal of biological macromolecules 2018 Apr 1;109:1154-1163
International journal of biological macromolecules 2018 Apr 1;109:1154-1163
Volatile Oil from Amomi Fructus Attenuates 5-Fluorouracil-Induced Intestinal Mucositis.
Zhang T, Lu SH, Bi Q, Liang L, Wang YF, Yang XX, Gu W, Yu J
Frontiers in pharmacology 2017;8:786
Frontiers in pharmacology 2017;8:786
Inhibition of the TRPM2 and TRPV1 Channels through Hypericum perforatum in Sciatic Nerve Injury-induced Rats Demonstrates their Key Role in Apoptosis and Mitochondrial Oxidative Stress of Sciatic Nerve and Dorsal Root Ganglion.
Uslusoy F, Nazıroğlu M, Çiğ B
Frontiers in physiology 2017;8:335
Frontiers in physiology 2017;8:335
Whole exome-wide association study identifies a missense variant in SLC2A4RG associated with glioblastoma risk.
Zhao Y, Yun D, Zou X, Jiang T, Li G, Hu L, Chen J, Xu J, Mao Y, Chen H, Lu D
American journal of cancer research 2017;7(9):1937-1947
American journal of cancer research 2017;7(9):1937-1947
Inhibition of HIF-1α by PX-478 suppresses tumor growth of esophageal squamous cell cancer in vitro and in vivo.
Zhu Y, Zang Y, Zhao F, Li Z, Zhang J, Fang L, Li M, Xing L, Xu Z, Yu J
American journal of cancer research 2017;7(5):1198-1212
American journal of cancer research 2017;7(5):1198-1212
Rosiglitazone Inhibits Angiotensin II-Induced Proliferation of Glomerular Mesangial Cells via the Gαq/Plcβ4/TRPC Signaling Pathway.
Wei L, Mao J, Lu J, Gao J, Zhu D, Tian L, Chen Z, Jia L, Wang L, Fu R
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(6):2228-2242
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(6):2228-2242
Ox-LDL-Induced MicroRNA-155 Promotes Autophagy in Human Endothelial Cells via Repressing the Rheb/ mTOR Pathway.
Lv J, Yang L, Guo R, Shi Y, Zhang Z, Ye J
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(4):1436-1448
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(4):1436-1448
Chondroprotective Effects and Multitarget Mechanisms of Fu Yuan Capsule in a Rat Osteoarthritis Model.
Zeng L, Xiao CZ, Deng ZT, Li RH
Evidence-based complementary and alternative medicine : eCAM 2017;2017:8985623
Evidence-based complementary and alternative medicine : eCAM 2017;2017:8985623
Electroacupuncture Improved Hippocampal Neurogenesis following Traumatic Brain Injury in Mice through Inhibition of TLR4 Signaling Pathway.
Ye Y, Yang Y, Chen C, Li Z, Jia Y, Su X, Wang C, He X
Stem cells international 2017;2017:5841814
Stem cells international 2017;2017:5841814
Pretreatment Donors after Circulatory Death with Simvastatin Alleviates Liver Ischemia Reperfusion Injury through a KLF2-Dependent Mechanism in Rat.
Liu Z, Zhang X, Xiao Q, Ye S, Lai CH, Luo J, Huang X, Wang W, Zeng C, Zhong Z, Fan X, Xia Z, Xiong Y, Mao X, Ye Q, Wang Y
Oxidative medicine and cellular longevity 2017;2017:3861914
Oxidative medicine and cellular longevity 2017;2017:3861914
Differential inhibition of activity, activation and gene expression of MMP-9 in THP-1 cells by azithromycin and minocycline versus bortezomib: A comparative study.
Vandooren J, Knoops S, Aldinucci Buzzo JL, Boon L, Martens E, Opdenakker G, Kolaczkowska E
PloS one 2017;12(4):e0174853
PloS one 2017;12(4):e0174853
Hyperlipidemia impairs erectile function in rats by causing cavernosal fibrosis.
Li R, Cui K, Wang T, Wang S, Li X, Qiu J, Yu G, Liu J, Wen B, Rao K
Andrologia 2017 Sep;49(7)
Andrologia 2017 Sep;49(7)
Mechanism of Lycium barbarum polysaccharides on primary cultured rat hippocampal neurons.
Zhao P, Ma NT, Chang RY, Li YX, Hao YJ, Yang WL, Zheng J, Niu Y, Sun T, Yu JQ
Cell and tissue research 2017 Sep;369(3):455-465
Cell and tissue research 2017 Sep;369(3):455-465
Histone variant H3.3 orchestrates neural stem cell differentiation in the developing brain.
Xia W, Jiao J
Cell death and differentiation 2017 Sep;24(9):1548-1563
Cell death and differentiation 2017 Sep;24(9):1548-1563
Hydrogen sulfide prevents homocysteine‑induced endoplasmic reticulum stress in PC12 cells by upregulating SIRT‑1.
Wang CY, Zou W, Liang XY, Jiang ZS, Li X, Wei HJ, Tang YY, Zhang P, Tang XQ
Molecular medicine reports 2017 Sep;16(3):3587-3593
Molecular medicine reports 2017 Sep;16(3):3587-3593
Exosomes derived from bone marrow stromal cells decrease the sensitivity of leukemic cells to etoposide.
Wang J, Li D, Zhuang Y, Fu J, Li X, Shi Q, Ju X
Oncology letters 2017 Sep;14(3):3082-3088
Oncology letters 2017 Sep;14(3):3082-3088
Roux-en-Y gastric bypass surgery suppresses hypothalamic PTP1B protein level and alleviates leptin resistance in obese rats.
Liu JY, Mu S, Zhang SP, Guo W, Li QF, Xiao XQ, Zhang J, Wang ZH
Experimental and therapeutic medicine 2017 Sep;14(3):2536-2542
Experimental and therapeutic medicine 2017 Sep;14(3):2536-2542
Low Frequency Magnetic Fields Induce Autophagy-associated Cell Death in Lung Cancer through miR-486-mediated Inhibition of Akt/mTOR Signaling Pathway.
Xu Y, Wang Y, Yao A, Xu Z, Dou H, Shen S, Hou Y, Wang T
Scientific reports 2017 Sep 18;7(1):11776
Scientific reports 2017 Sep 18;7(1):11776
AMPK activation-dependent autophagy compromises oleanolic acid-induced cytotoxicity in human bladder cancer cells.
Song Y, Zhang P, Sun Y, Li X, Chen L, Xiao Y, Xing Y
Oncotarget 2017 Sep 15;8(40):67942-67954
Oncotarget 2017 Sep 15;8(40):67942-67954
Downregulation of BZW2 inhibits osteosarcoma cell growth by inactivating the Akt/mTOR signaling pathway.
Cheng DD, Li SJ, Zhu B, Yuan T, Yang QC, Fan CY
Oncology reports 2017 Oct;38(4):2116-2122
Oncology reports 2017 Oct;38(4):2116-2122
Role of autophagy in cadmium-induced testicular injury.
Wang YJ, Yan J, Yin F, Li L, Qin YG, Meng CY, Lu RF, Guo L
Human & experimental toxicology 2017 Oct;36(10):1039-1048
Human & experimental toxicology 2017 Oct;36(10):1039-1048
Effects of hydrogen sulfide on inducible nitric oxide synthase activity and expression of cardiomyocytes in diabetic rats.
Yang R, Jia Q, Liu XF, Wang YY, Ma SF
Molecular medicine reports 2017 Oct;16(4):5277-5284
Molecular medicine reports 2017 Oct;16(4):5277-5284
Antiplatelet drug ticagrelor delays gastric ulcer healing in rats.
Li JJ, Wu XY, Chen JL, Chen GR, Xu J, Gu Y, Song HP
Experimental and therapeutic medicine 2017 Oct;14(4):3774-3779
Experimental and therapeutic medicine 2017 Oct;14(4):3774-3779
HOTAIR regulates HK2 expression by binding endogenous miR-125 and miR-143 in oesophageal squamous cell carcinoma progression.
Ma J, Fan Y, Feng T, Chen F, Xu Z, Li S, Lin Q, He X, Shi W, Liu Y, Liu Z, Zhu B, Cao X
Oncotarget 2017 Oct 17;8(49):86410-86422
Oncotarget 2017 Oct 17;8(49):86410-86422
Functional characterization of a novel transcript of ERCC1 in chemotherapy resistance of ovarian cancer.
Liu J, Zhang L, Mao P, Jiang G, Liu L, Wang J, Yang W, Owusu L, Li W
Oncotarget 2017 Oct 17;8(49):85759-85771
Oncotarget 2017 Oct 17;8(49):85759-85771
A novel protein derived from lamprey supraneural body tissue with efficient cytocidal actions against tumor cells.
Pang Y, Li C, Wang S, Ba W, Yu T, Pei G, Bi D, Liang H, Pan X, Zhu T, Gou M, Han Y, Li Q
Cell communication and signaling : CCS 2017 Oct 16;15(1):42
Cell communication and signaling : CCS 2017 Oct 16;15(1):42
LINC00461, a long non-coding RNA, is important for the proliferation and migration of glioma cells.
Yang Y, Ren M, Song C, Li D, Soomro SH, Xiong Y, Zhang H, Fu H
Oncotarget 2017 Oct 13;8(48):84123-84139
Oncotarget 2017 Oct 13;8(48):84123-84139
A high-fat, high-protein diet attenuates the negative impact of casein-induced chronic inflammation on testicular steroidogenesis and sperm parameters in adult mice.
Zhao JL, Zhao YY, Zhu WJ
General and comparative endocrinology 2017 Oct 1;252:48-59
General and comparative endocrinology 2017 Oct 1;252:48-59
Neuroprotective effect of liquiritin against neuropathic pain induced by chronic constriction injury of the sciatic nerve in mice.
Zhang MT, Wang B, Jia YN, Liu N, Ma PS, Gong SS, Niu Y, Sun T, Li YX, Yu JQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Nov;95:186-198
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Nov;95:186-198
Hepatoprotective effect of quercetin against LPS/d-GalN induced acute liver injury in mice by inhibiting the IKK/NF-κB and MAPK signal pathways.
Peng Z, Gong X, Yang Y, Huang L, Zhang Q, Zhang P, Wan R, Zhang B
International immunopharmacology 2017 Nov;52:281-289
International immunopharmacology 2017 Nov;52:281-289
Neuroprotective Effect of Chitosan Oligosaccharide on Hypoxic-Ischemic Brain Damage in Neonatal Rats.
Wu W, Wei W, Lu M, Zhu X, Liu N, Niu Y, Sun T, Li Y, Yu J
Neurochemical research 2017 Nov;42(11):3186-3198
Neurochemical research 2017 Nov;42(11):3186-3198
CMIP is oncogenic in human gastric cancer cells.
Zhang J, Huang J, Wang X, Chen W, Tang Q, Fang M, Qian Y
Molecular medicine reports 2017 Nov;16(5):7277-7286
Molecular medicine reports 2017 Nov;16(5):7277-7286
Dlitiazem inhibits the oxidative stress induced by angiotensin II through growth hormone secretagogue receptor type 1a in human umbilicus vein endothelial cells.
Zhou L, Yang M, Zuo S, Guan X, Wang J, Chen Q, Zuo X, Jia S, Guo R
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:76-82
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:76-82
Protective effects of aloperine on monocrotaline-induced pulmonary hypertension in rats.
Wu F, Hao Y, Yang J, Yao W, Xu Y, Yan L, Niu Y, Sun T, Yu J, Zhou R
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:632-641
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:632-641
ApoA-I/SR-BI modulates S1P/S1PR2-mediated inflammation through the PI3K/Akt signaling pathway in HUVECs.
Ren K, Lu YJ, Mo ZC, -Liu X, Tang ZL, Jiang Y, Peng XS, Li L, Zhang QH, Yi GH
Journal of physiology and biochemistry 2017 May;73(2):287-296
Journal of physiology and biochemistry 2017 May;73(2):287-296
Up-regulated BAFF and BAFF receptor expression in patients with intractable temporal lobe epilepsy and a pilocarpine-induced epilepsy rat model.
Ma L, Li R, Huang H, Yuan J, Ou S, Xu T, Yu X, Liu X, Chen Y
Seizure 2017 May;48:79-88
Seizure 2017 May;48:79-88
β-Caryophyllene Pretreatment Alleviates Focal Cerebral Ischemia-Reperfusion Injury by Activating PI3K/Akt Signaling Pathway.
Zhang Q, An R, Tian X, Yang M, Li M, Lou J, Xu L, Dong Z
Neurochemical research 2017 May;42(5):1459-1469
Neurochemical research 2017 May;42(5):1459-1469
AGR2 ameliorates tumor necrosis factor-α-induced epithelial barrier dysfunction via suppression of NF-κB p65-mediated MLCK/p-MLC pathway activation.
Ye X, Sun M
International journal of molecular medicine 2017 May;39(5):1206-1214
International journal of molecular medicine 2017 May;39(5):1206-1214
Relationship between abnormal TOX3 gene methylation and polycystic ovarian syndrome.
Ning Z, Jiayi L, Jian R, Wanli X
European review for medical and pharmacological sciences 2017 May;21(9):2034-2038
European review for medical and pharmacological sciences 2017 May;21(9):2034-2038
Icariin inhibits MMP‑1, MMP‑3 and MMP‑13 expression through MAPK pathways in IL‑1β‑stimulated SW1353 chondrosarcoma cells.
Zeng L, Rong XF, Li RH, Wu XY
Molecular medicine reports 2017 May;15(5):2853-2858
Molecular medicine reports 2017 May;15(5):2853-2858
A novel role of fragile X mental retardation protein in pre-mRNA alternative splicing through RNA-binding protein 14.
Zhou LT, Ye SH, Yang HX, Zhou YT, Zhao QH, Sun WW, Gao MM, Yi YH, Long YS
Neuroscience 2017 May 4;349:64-75
Neuroscience 2017 May 4;349:64-75
PLAA Mutations Cause a Lethal Infantile Epileptic Encephalopathy by Disrupting Ubiquitin-Mediated Endolysosomal Degradation of Synaptic Proteins.
Hall EA, Nahorski MS, Murray LM, Shaheen R, Perkins E, Dissanayake KN, Kristaryanto Y, Jones RA, Vogt J, Rivagorda M, Handley MT, Mali GR, Quidwai T, Soares DC, Keighren MA, McKie L, Mort RL, Gammoh N, Garcia-Munoz A, Davey T, Vermeren M, Walsh D, Budd P, Aligianis IA, Faqeih E, Quigley AJ, Jackson IJ, Kulathu Y, Jackson M, Ribchester RR, von Kriegsheim A, Alkuraya FS, Woods CG, Maher ER, Mill P
American journal of human genetics 2017 May 4;100(5):706-724
American journal of human genetics 2017 May 4;100(5):706-724
The Long Noncoding RNA NEAT1 Exerts Antihantaviral Effects by Acting as Positive Feedback for RIG-I Signaling.
Ma H, Han P, Ye W, Chen H, Zheng X, Cheng L, Zhang L, Yu L, Wu X, Xu Z, Lei Y, Zhang F
Journal of virology 2017 May 1;91(9)
Journal of virology 2017 May 1;91(9)
The Anticonvulsant and Neuroprotective Effects of Oxysophocarpine on Pilocarpine-Induced Convulsions in Adult Male Mice.
Liu G, Wang J, Deng XH, Ma PS, Li FM, Peng XD, Niu Y, Sun T, Li YX, Yu JQ
Cellular and molecular neurobiology 2017 Mar;37(2):339-349
Cellular and molecular neurobiology 2017 Mar;37(2):339-349
KIAA1199 is induced by inflammation and enhances malignant phenotype in pancreatic cancer.
Kohi S, Sato N, Koga A, Matayoshi N, Hirata K
Oncotarget 2017 Mar 7;8(10):17156-17163
Oncotarget 2017 Mar 7;8(10):17156-17163
Generation and characteristics of human Sertoli cell line immortalized by overexpression of human telomerase.
Wen L, Yuan Q, Sun M, Niu M, Wang H, Fu H, Zhou F, Yao C, Wang X, Li Z, He Z
Oncotarget 2017 Mar 7;8(10):16553-16570
Oncotarget 2017 Mar 7;8(10):16553-16570
Beneficial effects of Lycium barbarum polysaccharide on spermatogenesis by improving antioxidant activity and inhibiting apoptosis in streptozotocin-induced diabetic male mice.
Shi GJ, Zheng J, Wu J, Qiao HQ, Chang Q, Niu Y, Sun T, Li YX, Yu JQ
Food & function 2017 Mar 22;8(3):1215-1226
Food & function 2017 Mar 22;8(3):1215-1226
Mitochondrial dynamics changes with age in an APPsw/PS1dE9 mouse model of Alzheimer's disease.
Xu LL, Shen Y, Wang X, Wei LF, Wang P, Yang H, Wang CF, Xie ZH, Bi JZ
Neuroreport 2017 Mar 1;28(4):222-228
Neuroreport 2017 Mar 1;28(4):222-228
HMGB1-induced autophagy: a new pathway to maintain Treg function during chronic hepatitis B virus infection.
Cheng LS, Li J, Liu Y, Wang FP, Wang SQ, She WM, Wu SD, Qi XL, Zhou YP, Jiang W
Clinical science (London, England : 1979) 2017 Mar 1;131(5):381-394
Clinical science (London, England : 1979) 2017 Mar 1;131(5):381-394
TGF-β1 promotes human hepatic carcinoma HepG2 cells invasion by upregulating autophagy.
Ma CL, Qiao S, Li YC, Wang XF, Sun RJ, Zhang X, Qian RK, Song SD
European review for medical and pharmacological sciences 2017 Jun;21(11):2604-2610
European review for medical and pharmacological sciences 2017 Jun;21(11):2604-2610
DDX50 inhibits the replication of dengue virus 2 by upregulating IFN-β production.
Han P, Ye W, Lv X, Ma H, Weng D, Dong Y, Cheng L, Chen H, Zhang L, Xu Z, Lei Y, Zhang F
Archives of virology 2017 Jun;162(6):1487-1494
Archives of virology 2017 Jun;162(6):1487-1494
Generation and characterization of induced pluripotent stem cells from guinea pig fetal fibroblasts.
Wu Y, Li O, He C, Li Y, Li M, Liu XL, Wang Y, He Y
Molecular medicine reports 2017 Jun;15(6):3690-3698
Molecular medicine reports 2017 Jun;15(6):3690-3698
Esculetin induces apoptosis of SMMC-7721 cells through IGF-1/PI3K/Akt-mediated mitochondrial pathways.
Li J, Li S, Wang X, Wang H
Canadian journal of physiology and pharmacology 2017 Jul;95(7):787-794
Canadian journal of physiology and pharmacology 2017 Jul;95(7):787-794
Estrogen receptor-α36 is involved in icaritin induced growth inhibition of triple-negative breast cancer cells.
Wang X, Zheng N, Dong J, Wang X, Liu L, Huang J
The Journal of steroid biochemistry and molecular biology 2017 Jul;171:318-327
The Journal of steroid biochemistry and molecular biology 2017 Jul;171:318-327
Nrf2-Knockout Protects from Intestinal Injuries in C57BL/6J Mice Following Abdominal Irradiation with γ Rays.
Yang W, Sun Z, Yang B, Wang Q
International journal of molecular sciences 2017 Jul 31;18(8)
International journal of molecular sciences 2017 Jul 31;18(8)
Hypoxia-inducible factor-1 alpha is involved in RIP-induced necroptosis caused by in vitro and in vivo ischemic brain injury.
Yang XS, Yi TL, Zhang S, Xu ZW, Yu ZQ, Sun HT, Yang C, Tu Y, Cheng SX
Scientific reports 2017 Jul 19;7(1):5818
Scientific reports 2017 Jul 19;7(1):5818
SHIP, a novel factor to ameliorate extracellular matrix accumulation via suppressing PI3K/Akt/CTGF signaling in diabetic kidney disease.
Li F, Li L, Cheng M, Wang X, Hao J, Liu S, Duan H
Biochemical and biophysical research communications 2017 Jan 22;482(4):1477-1483
Biochemical and biophysical research communications 2017 Jan 22;482(4):1477-1483
Effect of Oleracein E, a Neuroprotective Tetrahydroisoquinoline, on Rotenone-Induced Parkinson's Disease Cell and Animal Models.
Sun H, He X, Liu C, Li L, Zhou R, Jin T, Yue S, Feng D, Gong J, Sun J, Ji J, Xiang L
ACS chemical neuroscience 2017 Jan 18;8(1):155-164
ACS chemical neuroscience 2017 Jan 18;8(1):155-164
BMP4 promotes mouse iPS cell differentiation to male germ cells via Smad1/5, Gata4, Id1 and Id2.
Yang S, Yuan Q, Niu M, Hou J, Zhu Z, Sun M, Li Z, He Z
Reproduction (Cambridge, England) 2017 Feb;153(2):211-220
Reproduction (Cambridge, England) 2017 Feb;153(2):211-220
Induction of apoptosis by FFJ-5, a novel naphthoquinone compound, occurs via downregulation of PKM2 in A549 and HepG2 cells.
Wei X, Li M, Ma M, Jia H, Zhang Y, Kang W, Wang T, Shi X
Oncology letters 2017 Feb;13(2):791-799
Oncology letters 2017 Feb;13(2):791-799
Coptisine from Rhizoma Coptidis Suppresses HCT-116 Cells-related Tumor Growth in vitro and in vivo.
Huang T, Xiao Y, Yi L, Li L, Wang M, Tian C, Ma H, He K, Wang Y, Han B, Ye X, Li X
Scientific reports 2017 Feb 6;7:38524
Scientific reports 2017 Feb 6;7:38524
TRIM14 regulates cell proliferation and invasion in osteosarcoma via promotion of the AKT signaling pathway.
Xu G, Guo Y, Xu D, Wang Y, Shen Y, Wang F, Lv Y, Song F, Jiang D, Zhang Y, Lou Y, Meng Y, Yang Y, Kang Y
Scientific reports 2017 Feb 16;7:42411
Scientific reports 2017 Feb 16;7:42411
Antitumor effects of baicalin on ovarian cancer cells through induction of cell apoptosis and inhibition of cell migration in vitro.
Gao C, Zhou Y, Li H, Cong X, Jiang Z, Wang X, Cao R, Tian W
Molecular medicine reports 2017 Dec;16(6):8729-8734
Molecular medicine reports 2017 Dec;16(6):8729-8734
Chloroform extract of Hedyotis diffusa Willd inhibits viability of human colorectal cancer cells via suppression of AKT and ERK signaling pathways.
Yan Z, Feng J, Peng J, Lai Z, Zhang L, Jin Y, Yang H, Chen W, Lin J
Oncology letters 2017 Dec;14(6):7923-7930
Oncology letters 2017 Dec;14(6):7923-7930
Inhibition of chemotherapy-induced apoptosis of testicular cells by squid ink polysaccharide.
Gu YP, Yang XM, Duan ZH, Luo P, Shang JH, Xiao W, Tao YX, Zhang DY, Zhang YB, Liu HZ
Experimental and therapeutic medicine 2017 Dec;14(6):5889-5895
Experimental and therapeutic medicine 2017 Dec;14(6):5889-5895
Involvement of TRPM2 and TRPV1 channels on hyperalgesia, apoptosis and oxidative stress in rat fibromyalgia model: Protective role of selenium.
Yüksel E, Nazıroğlu M, Şahin M, Çiğ B
Scientific reports 2017 Dec 13;7(1):17543
Scientific reports 2017 Dec 13;7(1):17543
Inhibition of Calcineurin A by FK506 Suppresses Seizures and Reduces the Expression of GluN2B in Membrane Fraction.
Wen Y, Fu P, Wu K, Si K, Xie Y, Dan W, Zhan Y, Shi Q
Neurochemical research 2017 Aug;42(8):2154-2166
Neurochemical research 2017 Aug;42(8):2154-2166
miR-367 promotes tumor growth by inhibiting FBXW7 in NSCLC.
Xiao G, Gao X, Sun X, Yang C, Zhang B, Sun R, Huang G, Li X, Liu J, Du N, Liu D, Liang R, Ren H, Qin S
Oncology reports 2017 Aug;38(2):1190-1198
Oncology reports 2017 Aug;38(2):1190-1198
IGFBP-rP1 acts as a potential tumor suppressor via the suppression of ERK signaling pathway in endometrial cancer cells.
Ma Y, Jiang J, Zhang Y, Ding Y, Xu T, Lu B
Molecular medicine reports 2017 Aug;16(2):1445-1450
Molecular medicine reports 2017 Aug;16(2):1445-1450
Src Homology 2 Domain-Containing Inositol 5'-Phosphatase Ameliorates High Glucose-Induced Extracellular Matrix Deposition via the Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway in Renal Tubular Epithelial Cells.
Li F, Li L, Hao J, Liu S, Duan H
Journal of cellular biochemistry 2017 Aug;118(8):2271-2284
Journal of cellular biochemistry 2017 Aug;118(8):2271-2284
miR-133b Inhibits Cell Growth, Migration, and Invasion by Targeting MMP9 in Non-Small Cell Lung Cancer.
Zhen Y, Liu J, Huang Y, Wang Y, Li W, Wu J
Oncology research 2017 Aug 7;25(7):1109-1116
Oncology research 2017 Aug 7;25(7):1109-1116
Melatonin ameliorates restraint stress-induced oxidative stress and apoptosis in testicular cells via NF-κB/iNOS and Nrf2/ HO-1 signaling pathway.
Guo Y, Sun J, Li T, Zhang Q, Bu S, Wang Q, Lai D
Scientific reports 2017 Aug 29;7(1):9599
Scientific reports 2017 Aug 29;7(1):9599
Epigallocatechin-3-gallate inhibits H(2)O(2)-induced apoptosis in Mouse Vascular Smooth Muscle Cells via 67kD Laminin Receptor.
Yan X, Li Y, Yu H, Wang W, Wu C, Yang Y, Hu Y, Shi X, Li J
Scientific reports 2017 Aug 10;7(1):7774
Scientific reports 2017 Aug 10;7(1):7774
Phosphocreatine protects endothelial cells from Methylglyoxal induced oxidative stress and apoptosis via the regulation of PI3K/Akt/eNOS and NF-κB pathway.
Chu P, Han G, Ahsan A, Sun Z, Liu S, Zhang Z, Sun B, Song Y, Lin Y, Peng J, Tang Z
Vascular pharmacology 2017 Apr;91:26-35
Vascular pharmacology 2017 Apr;91:26-35
Long non-coding RNA TUG1 promotes cell proliferation and metastasis by negatively regulating miR-300 in gallbladder carcinoma.
Ma F, Wang SH, Cai Q, Jin LY, Zhou D, Ding J, Quan ZW
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Apr;88:863-869
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Apr;88:863-869
The Circadian Gene Clock Regulates Bone Formation Via PDIA3.
Yuan G, Hua B, Yang Y, Xu L, Cai T, Sun N, Yan Z, Lu C, Qian R
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2017 Apr;32(4):861-871
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2017 Apr;32(4):861-871
Terrein performs antitumor functions on esophageal cancer cells by inhibiting cell proliferation and synergistic interaction with cisplatin.
Wu Y, Zhu Y, Li S, Zeng M, Chu J, Hu P, Li J, Guo Q, Lv XB, Huang G
Oncology letters 2017 Apr;13(4):2805-2810
Oncology letters 2017 Apr;13(4):2805-2810
miR-150 is downregulated in osteosarcoma and suppresses cell proliferation, migration and invasion by targeting ROCK1.
Li CH, Yu TB, Qiu HW, Zhao X, Zhou CL, Qi C
Oncology letters 2017 Apr;13(4):2191-2197
Oncology letters 2017 Apr;13(4):2191-2197
Boschniakia Rossica Polysaccharide Triggers Laryngeal Carcinoma Cell Apoptosis by Regulating Expression of Bcl-2, Caspase-3, and P53.
Yao C, Cao X, Fu Z, Tian J, Dong W, Xu J, An K, Zhai L, Yu J
Medical science monitor : international medical journal of experimental and clinical research 2017 Apr 29;23:2059-2064
Medical science monitor : international medical journal of experimental and clinical research 2017 Apr 29;23:2059-2064
Tumor-associated macrophages promote Ezrin phosphorylation-mediated epithelial-mesenchymal transition in lung adenocarcinoma through FUT4/LeY up-regulation.
Wang A, Lu C, Ning Z, Gao W, Xie Y, Zhang N, Liang J, Abbasi FS, Yan Q, Liu J
Oncotarget 2017 Apr 25;8(17):28247-28259
Oncotarget 2017 Apr 25;8(17):28247-28259
The acute exposure of tetrachloro-p-benzoquinone (a.k.a. chloranil) triggers inflammation and neurological dysfunction via Toll-like receptor 4 signaling: The protective role of melatonin preconditioning.
Fu J, Xia X, Liu Z, Wang Y, Wang Y, Shi Q, Song X, Song E, Song Y
Toxicology 2017 Apr 15;381:39-50
Toxicology 2017 Apr 15;381:39-50
Enhanced tenogenic differentiation and tendon-like tissue formation by CHIP overexpression in tendon-derived stem cells.
Han W, Chen L, Liu J, Guo A
Acta biochimica et biophysica Sinica 2017 Apr 1;49(4):311-317
Acta biochimica et biophysica Sinica 2017 Apr 1;49(4):311-317
1,2-Dichloroethane impairs glucose and lipid homeostasis in the livers of NIH Swiss mice.
Wang T, Xu D, Fan Q, Rong W, Zheng J, Gao C, Li G, Zeng N, Guo T, Zeng L, Wang F, Xiao C, Cai L, Tang S, Deng X, Yin X, Huang M, Lu F, Hu Q, Chen W, Huang Z, Wang Q
Toxicology 2017 Apr 1;380:38-49
Toxicology 2017 Apr 1;380:38-49
High-dose irradiation in combination with toll-like receptor 9 agonist CpG oligodeoxynucleotide 7909 downregulates PD-L1 expression via the NF-κB signaling pathway in non-small cell lung cancer cells.
Chen X, Zhang Q, Luo Y, Gao C, Zhuang X, Xu G, Qiao T
OncoTargets and therapy 2016;9:6511-6518
OncoTargets and therapy 2016;9:6511-6518
Radiation promotes epithelial-to-mesenchymal transition and invasion of pancreatic cancer cell by activating carcinoma-associated fibroblasts.
Li D, Qu C, Ning Z, Wang H, Zang K, Zhuang L, Chen L, Wang P, Meng Z
American journal of cancer research 2016;6(10):2192-2206
American journal of cancer research 2016;6(10):2192-2206
Targeting Dynamin 2 as a Novel Pathway to Inhibit Cardiomyocyte Apoptosis Following Oxidative Stress.
Gao D, Yang J, Wu Y, Wang Q, Wang Q, Lai EY, Zhu J
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;39(6):2121-2134
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;39(6):2121-2134
N-Methyl-D-aspartate Receptor Excessive Activation Inhibited Fetal Rat Lung Development In Vivo and In Vitro.
Liao Z, Zhou X, Luo Z, Huo H, Wang M, Yu X, Cao C, Ding Y, Xiong Z, Yue S
BioMed research international 2016;2016:5843981
BioMed research international 2016;2016:5843981
The Generation and Characterization of Recombinant Protein and Antibodies of Clostridium perfringens Beta2 Toxin.
Zeng J, Song F, Yang Y, Ma C, Deng G, Li Y, Wang Y, Liu X
Journal of immunology research 2016;2016:5708468
Journal of immunology research 2016;2016:5708468
Quantitative Proteomic Profiling the Molecular Signatures of Annexin A5 in Lung Squamous Carcinoma Cells.
Sun B, Bai Y, Zhang L, Gong L, Qi X, Li H, Wang F, Chi X, Jiang Y, Shao S
PloS one 2016;11(9):e0163622
PloS one 2016;11(9):e0163622
The long noncoding RNA MALAT1 regulates the lipopolysaccharide-induced inflammatory response through its interaction with NF-κB.
Zhao G, Su Z, Song D, Mao Y, Mao X
FEBS letters 2016 Sep;590(17):2884-95
FEBS letters 2016 Sep;590(17):2884-95
Lactobacillus rhamnosus induced epithelial cell apoptosis, ameliorates inflammation and prevents colon cancer development in an animal model.
Gamallat Y, Meyiah A, Kuugbee ED, Hago AM, Chiwala G, Awadasseid A, Bamba D, Zhang X, Shang X, Luo F, Xin Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Oct;83:536-541
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Oct;83:536-541
From the Cover: Tetrachlorobenzoquinone Exerts Neurological Proinflammatory Activity by Promoting HMGB1 Release, Which Induces TLR4 Clustering within the Lipid Raft.
Fu J, Shi Q, Song X, Liu Z, Wang Y, Wang Y, Song E, Song Y
Toxicological sciences : an official journal of the Society of Toxicology 2016 Oct;153(2):303-15
Toxicological sciences : an official journal of the Society of Toxicology 2016 Oct;153(2):303-15
Hydrogen Sulfide and Carbon Monoxide Protect Gastric Mucosa Compromised by Mild Stress Against Alendronate Injury.
Magierowski M, Magierowska K, Szmyd J, Surmiak M, Sliwowski Z, Kwiecien S, Brzozowski T
Digestive diseases and sciences 2016 Nov;61(11):3176-3189
Digestive diseases and sciences 2016 Nov;61(11):3176-3189
Quantitative proteomics reveals molecular mechanism of gamabufotalin and its potential inhibition on Hsp90 in lung cancer.
Zhang L, Yu Z, Wang Y, Wang X, Zhang L, Wang C, Yue Q, Wang X, Deng S, Huo X, Tian X, Huang S, Zhang B, Ma X
Oncotarget 2016 Nov 22;7(47):76551-76564
Oncotarget 2016 Nov 22;7(47):76551-76564
Progranulin deficiency leads to severe inflammation, lung injury and cell death in a mouse model of endotoxic shock.
Yu Y, Xu X, Liu L, Mao S, Feng T, Lu Y, Cheng Y, Wang H, Zhao W, Tang W
Journal of cellular and molecular medicine 2016 Mar;20(3):506-17
Journal of cellular and molecular medicine 2016 Mar;20(3):506-17
The tumor suppressor PTEN has a critical role in antiviral innate immunity.
Li S, Zhu M, Pan R, Fang T, Cao YY, Chen S, Zhao X, Lei CQ, Guo L, Chen Y, Li CM, Jokitalo E, Yin Y, Shu HB, Guo D
Nature immunology 2016 Mar;17(3):241-9
Nature immunology 2016 Mar;17(3):241-9
AMPK-mediated up-regulation of mTORC2 and MCL-1 compromises the anti-cancer effects of aspirin.
Gao M, Kong Q, Hua H, Yin Y, Wang J, Luo T, Jiang Y
Oncotarget 2016 Mar 29;7(13):16349-61
Oncotarget 2016 Mar 29;7(13):16349-61
Potassium supplementation inhibits IL-17A production induced by salt loading in human T lymphocytes via p38/MAPK-SGK1 pathway.
Wen W, Wan Z, Ren K, Zhou D, Gao Q, Wu Y, Wang L, Yuan Z, Zhou J
Experimental and molecular pathology 2016 Jun;100(3):370-7
Experimental and molecular pathology 2016 Jun;100(3):370-7
Myricetin ameliorates brain injury and neurological deficits via Nrf2 activation after experimental stroke in middle-aged rats.
Wu S, Yue Y, Peng A, Zhang L, Xiang J, Cao X, Ding H, Yin S
Food & function 2016 Jun 15;7(6):2624-34
Food & function 2016 Jun 15;7(6):2624-34
Carboxy-terminal modulator protein attenuated extracellular matrix deposit by inhibiting phospho-Akt, TGF-β1 and α-SMA in kidneys of diabetic mice.
Chen N, Hao J, Li L, Li F, Liu S, Duan H
Biochemical and biophysical research communications 2016 Jun 10;474(4):753-760
Biochemical and biophysical research communications 2016 Jun 10;474(4):753-760
Lipodystrophy and severe metabolic dysfunction in mice with adipose tissue-specific insulin receptor ablation.
Qiang G, Whang Kong H, Xu S, Pham HA, Parlee SD, Burr AA, Gil V, Pang J, Hughes A, Gu X, Fantuzzi G, MacDougald OA, Liew CW
Molecular metabolism 2016 Jul;5(7):480-490
Molecular metabolism 2016 Jul;5(7):480-490
miR-223 enhances the sensitivity of non-small cell lung cancer cells to erlotinib by targeting the insulin-like growth factor-1 receptor.
Zhao FY, Han J, Chen XW, Wang J, Wang XD, Sun JG, Chen ZT
International journal of molecular medicine 2016 Jul;38(1):183-91
International journal of molecular medicine 2016 Jul;38(1):183-91
Development of a Biomimetic Chondroitin Sulfate-modified Hydrogel to Enhance the Metastasis of Tumor Cells.
Liu Y, Wang S, Sun D, Liu Y, Liu Y, Wang Y, Liu C, Wu H, Lv Y, Ren Y, Guo X, Sun G, Ma X
Scientific reports 2016 Jul 19;6:29858
Scientific reports 2016 Jul 19;6:29858
Novel Recombinant Protein FlaA N/C Protects against Radiation Injury via NF-κB Signaling.
Xu Y, Wu D, Fan Y, Li P, Du H, Shi J, Wang D, Zhou X
Radiation research 2016 Jan;185(1):77-86
Radiation research 2016 Jan;185(1):77-86
[Corrigendum] Cannabinoid WIN55, 212-2 induces cell cycle arrest and inhibits the proliferation and migration of human BEL7402 hepatocellular carcinoma cells.
Xu D, Wang J, Zhou Z, He Z, Zhao Q
Molecular medicine reports 2016 Jan;13(1):1054
Molecular medicine reports 2016 Jan;13(1):1054
Gamabufotalin, a major derivative of bufadienolide, inhibits VEGF-induced angiogenesis by suppressing VEGFR-2 signaling pathway.
Tang N, Shi L, Yu Z, Dong P, Wang C, Huo X, Zhang B, Huang S, Deng S, Liu K, Ma T, Wang X, Wu L, Ma XC
Oncotarget 2016 Jan 19;7(3):3533-47
Oncotarget 2016 Jan 19;7(3):3533-47
Bezafibrate-mizoribine interaction: Involvement of organic anion transporters OAT1 and OAT3 in rats.
Feng Y, Wang C, Liu Q, Meng Q, Huo X, Liu Z, Sun P, Yang X, Sun H, Qin J, Liu K
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2016 Jan 1;81:119-28
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2016 Jan 1;81:119-28
Nicotine Induced Murine Spermatozoa Apoptosis via Up-Regulation of Deubiquitinated RIP1 by Trim27 Promoter Hypomethylation.
Nie D, Zhang D, Dai J, Zhang M, Zhao X, Xu W, Chen Z, Wang L, Wang Z, Qiao Z
Biology of reproduction 2016 Feb;94(2):31
Biology of reproduction 2016 Feb;94(2):31
IL-17 intensifies IFN-γ-induced NOS2 upregulation in RAW 264.7 cells by further activating STAT1 and NF-κB.
Gao Q, Liu Y, Wu Y, Zhao Q, Wang L, Gao S, Wen W, Zhang W, Guo N, Zhou J, Yuan Z
International journal of molecular medicine 2016 Feb;37(2):347-58
International journal of molecular medicine 2016 Feb;37(2):347-58
[Correlation between uncoupling protein 2 expression and myocardial mitochondrial injury in rats with sepsis induced by lipopolysaccharide].
Huang JD, Chen SL, Lyu JJ, Liu C, Zeng QY
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 2016 Feb;18(2):159-64
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 2016 Feb;18(2):159-64
Effect of acute lipopolysaccharide-induced inflammation in intracerebroventricular-streptozotocin injected rats.
Murtishaw AS, Heaney CF, Bolton MM, Sabbagh JJ, Langhardt MA, Kinney JW
Neuropharmacology 2016 Feb;101:110-22
Neuropharmacology 2016 Feb;101:110-22
ApoA-I induces S1P release from endothelial cells through ABCA1 and SR-BI in a positive feedback manner.
Liu X, Ren K, Suo R, Xiong SL, Zhang QH, Mo ZC, Tang ZL, Jiang Y, Peng XS, Yi GH
Journal of physiology and biochemistry 2016 Dec;72(4):657-667
Journal of physiology and biochemistry 2016 Dec;72(4):657-667
Upregulated Expression of microRNA-16 Correlates with Th17/Treg Cell Imbalance in Patients with Rheumatoid Arthritis.
Wu YH, Liu W, Xue B, Zhang L, Liu XY, Liu B, Wang Y, Cai Y, Duan R
DNA and cell biology 2016 Dec;35(12):853-860
DNA and cell biology 2016 Dec;35(12):853-860
Establishment of a first-line second-line treatment model for human pulmonary adenocarcinoma.
Wang L, Wang Y, Guan Q, Liu Y, He T, Wang J
Oncology letters 2016 Dec;12(6):4461-4466
Oncology letters 2016 Dec;12(6):4461-4466
Interaction between endogenous carbon monoxide and hydrogen sulfide in the mechanism of gastroprotection against acute aspirin-induced gastric damage.
Magierowski M, Magierowska K, Hubalewska-Mazgaj M, Adamski J, Bakalarz D, Sliwowski Z, Pajdo R, Kwiecien S, Brzozowski T
Pharmacological research 2016 Dec;114:235-250
Pharmacological research 2016 Dec;114:235-250
Anti-tumor effects of osthole on ovarian cancer cells in vitro.
Jiang G, Liu J, Ren B, Tang Y, Owusu L, Li M, Zhang J, Liu L, Li W
Journal of ethnopharmacology 2016 Dec 4;193:368-376
Journal of ethnopharmacology 2016 Dec 4;193:368-376
Casitas B-cell lymphoma (Cbl) proteins protect mammary epithelial cells from proteotoxicity of active c-Src accumulation.
Mukhopadhyay C, Triplett A, Bargar T, Heckman C, Wagner KU, Naramura M
Proceedings of the National Academy of Sciences of the United States of America 2016 Dec 20;113(51):E8228-E8237
Proceedings of the National Academy of Sciences of the United States of America 2016 Dec 20;113(51):E8228-E8237
State estimation and prediction using clustered particle filters.
Lee Y, Majda AJ
Proceedings of the National Academy of Sciences of the United States of America 2016 Dec 20;113(51):14609-14614
Proceedings of the National Academy of Sciences of the United States of America 2016 Dec 20;113(51):14609-14614
Disrupting MALAT1/miR-200c sponge decreases invasion and migration in endometrioid endometrial carcinoma.
Li Q, Zhang C, Chen R, Xiong H, Qiu F, Liu S, Zhang M, Wang F, Wang Y, Zhou X, Xiao G, Wang X, Jiang Q
Cancer letters 2016 Dec 1;383(1):28-40
Cancer letters 2016 Dec 1;383(1):28-40
miR-1273g-3p modulates activation and apoptosis of hepatic stellate cells by directly targeting PTEN in HCV-related liver fibrosis.
Niu X, Fu N, Du J, Wang R, Wang Y, Zhao S, Du H, Wang B, Zhang Y, Sun D, Nan Y
FEBS letters 2016 Aug;590(16):2709-24
FEBS letters 2016 Aug;590(16):2709-24
Kelch-like Protein 21 (KLHL21) Targets IκB Kinase-β to Regulate Nuclear Factor κ-Light Chain Enhancer of Activated B Cells (NF-κB) Signaling Negatively.
Mei ZZ, Chen XY, Hu SW, Wang N, Ou XL, Wang J, Luo HH, Liu J, Jiang Y
The Journal of biological chemistry 2016 Aug 26;291(35):18176-89
The Journal of biological chemistry 2016 Aug 26;291(35):18176-89
MiR-770-5p inhibits cisplatin chemoresistance in human ovarian cancer by targeting ERCC2.
Zhao H, Yu X, Ding Y, Zhao J, Wang G, Wu X, Jiang J, Peng C, Guo GZ, Cui S
Oncotarget 2016 Aug 16;7(33):53254-53268
Oncotarget 2016 Aug 16;7(33):53254-53268
Calcium efflux from the endoplasmic reticulum regulates cisplatin-induced apoptosis in human cervical cancer HeLa cells.
Shen L, Wen N, Xia M, Zhang YU, Liu W, Xu YE, Sun L
Oncology letters 2016 Apr;11(4):2411-2419
Oncology letters 2016 Apr;11(4):2411-2419
Highly expressed UNC119 promotes hepatocellular carcinoma cell proliferation through Wnt/β-catenin signaling and predicts a poor prognosis.
Lei B, Chai W, Wang Z, Liu R
American journal of cancer research 2015;5(10):3123-34
American journal of cancer research 2015;5(10):3123-34
Study on the Dynamic Biological Characteristics of Sca-1(+) Hematopoietic Stem and Progenitor Cell Senescence.
Geng S, Mu XY, Chen XB, Hou JY, Jia DY, Xu CY, Wang YP
Stem cells international 2015;2015:954120
Stem cells international 2015;2015:954120
Liquiritigenin Protects Rats from Carbon Tetrachloride Induced Hepatic Injury through PGC-1α Pathway.
Zhang Y, He Y, Yu H, Ma F, Wu J, Zhang X
Evidence-based complementary and alternative medicine : eCAM 2015;2015:649568
Evidence-based complementary and alternative medicine : eCAM 2015;2015:649568
MYBL2 guides autophagy suppressor VDAC2 in the developing ovary to inhibit autophagy through a complex of VDAC2-BECN1-BCL2L1 in mammals.
Yuan J, Zhang Y, Sheng Y, Fu X, Cheng H, Zhou R
Autophagy 2015;11(7):1081-98
Autophagy 2015;11(7):1081-98
Panaxadiol Saponin and Dexamethasone Improve Renal Function in Lipopolysaccharide-Induced Mouse Model of Acute Kidney Injury.
Chen Y, Du Y, Li Y, Wang X, Gao P, Yang G, Fang Y, Meng Y, Zhao X
PloS one 2015;10(7):e0134653
PloS one 2015;10(7):e0134653
The Nucleocapsid Protein of Coronaviruses Acts as a Viral Suppressor of RNA Silencing in Mammalian Cells.
Cui L, Wang H, Ji Y, Yang J, Xu S, Huang X, Wang Z, Qin L, Tien P, Zhou X, Guo D, Chen Y
Journal of virology 2015 Sep;89(17):9029-43
Journal of virology 2015 Sep;89(17):9029-43
Matrine attenuates focal cerebral ischemic injury by improving antioxidant activity and inhibiting apoptosis in mice.
Zhao P, Zhou R, Zhu XY, Hao YJ, Li N, Wang J, Niu Y, Sun T, Li YX, Yu JQ
International journal of molecular medicine 2015 Sep;36(3):633-44
International journal of molecular medicine 2015 Sep;36(3):633-44
FUS Interacts with HSP60 to Promote Mitochondrial Damage.
Deng J, Yang M, Chen Y, Chen X, Liu J, Sun S, Cheng H, Li Y, Bigio EH, Mesulam M, Xu Q, Du S, Fushimi K, Zhu L, Wu JY
PLoS genetics 2015 Sep;11(9):e1005357
PLoS genetics 2015 Sep;11(9):e1005357
Exposure to airborne PM2.5 suppresses microRNA expression and deregulates target oncogenes that cause neoplastic transformation in NIH3T3 cells.
Liu C, Guo H, Cheng X, Shao M, Wu C, Wang S, Li H, Wei L, Gao Y, Tan W, Cheng S, Wu T, Yu D, Lin D
Oncotarget 2015 Oct 6;6(30):29428-39
Oncotarget 2015 Oct 6;6(30):29428-39
HBx-related long non-coding RNA DBH-AS1 promotes cell proliferation and survival by activating MAPK signaling in hepatocellular carcinoma.
Huang JL, Ren TY, Cao SW, Zheng SH, Hu XM, Hu YW, Lin L, Chen J, Zheng L, Wang Q
Oncotarget 2015 Oct 20;6(32):33791-804
Oncotarget 2015 Oct 20;6(32):33791-804
Olaquindox induces DNA damage via the lysosomal and mitochondrial pathway involving ROS production and p53 activation in HEK293 cells.
Yang Y, Jiang L, She Y, Chen M, Li Q, Yang G, Geng C, Tang L, Zhong L, Jiang L, Liu X
Environmental toxicology and pharmacology 2015 Nov;40(3):792-9
Environmental toxicology and pharmacology 2015 Nov;40(3):792-9
Inhibition of migration and induction of apoptosis in LoVo human colon cancer cells by polysaccharides from Ganoderma lucidum.
Liang ZE, Yi YJ, Guo YT, Wang RC, Hu QL, Xiong XY
Molecular medicine reports 2015 Nov;12(5):7629-36
Molecular medicine reports 2015 Nov;12(5):7629-36
Establishment and Characterization of Human Germline Stem Cell Line with Unlimited Proliferation Potentials and no Tumor Formation.
Hou J, Niu M, Liu L, Zhu Z, Wang X, Sun M, Yuan Q, Yang S, Zeng W, Liu Y, Li Z, He Z
Scientific reports 2015 Nov 20;5:16922
Scientific reports 2015 Nov 20;5:16922
A Critical Role for Cysteine 57 in the Biological Functions of Selenium Binding Protein-1.
Ying Q, Ansong E, Diamond AM, Yang W
International journal of molecular sciences 2015 Nov 18;16(11):27599-608
International journal of molecular sciences 2015 Nov 18;16(11):27599-608
MicroRNA-206 attenuates tumor proliferation and migration involving the downregulation of NOTCH3 in colorectal cancer.
Wang XW, Xi XQ, Wu J, Wan YY, Hui HX, Cao XF
Oncology reports 2015 Mar;33(3):1402-10
Oncology reports 2015 Mar;33(3):1402-10
Reactive stroma component COL6A1 is upregulated in castration-resistant prostate cancer and promotes tumor growth.
Zhu YP, Wan FN, Shen YJ, Wang HK, Zhang GM, Ye DW
Oncotarget 2015 Jun 10;6(16):14488-96
Oncotarget 2015 Jun 10;6(16):14488-96
Tetrachlorobenzoquinone triggers the cleavage of Bid and promotes the cross-talk of extrinsic and intrinsic apoptotic signalings in pheochromocytoma (PC) 12 cells.
Hu L, Su C, Song X, Shi Q, Fu J, Xia X, Xu D, Song E, Song Y
Neurotoxicology 2015 Jul;49:149-57
Neurotoxicology 2015 Jul;49:149-57
Trophoblast glycoprotein promotes pancreatic ductal adenocarcinoma cell metastasis through Wnt/planar cell polarity signaling.
He P, Jiang S, Ma M, Wang Y, Li R, Fang F, Tian G, Zhang Z
Molecular medicine reports 2015 Jul;12(1):503-9
Molecular medicine reports 2015 Jul;12(1):503-9
The safety and anti-hypercholesterolemic effect of coptisine in Syrian golden hamsters.
He K, Ye X, Wu H, Wang Y, Zou Z, Ning N, Hu Y, Chen B, Fang X, Li X
Lipids 2015 Feb;50(2):185-94
Lipids 2015 Feb;50(2):185-94
SPAG6 silencing inhibits the growth of the malignant myeloid cell lines SKM-1 and K562 via activating p53 and caspase activation-dependent apoptosis.
Yang B, Wang L, Luo X, Chen L, Yang Z, Liu L
International journal of oncology 2015 Feb;46(2):649-56
International journal of oncology 2015 Feb;46(2):649-56
Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice.
Shi Q, Song X, Fu J, Su C, Xia X, Song E, Song Y
International immunopharmacology 2015 Dec;29(2):722-729
International immunopharmacology 2015 Dec;29(2):722-729
Dynamic expression of miR-206-3p during mouse skin development is independent of keratinocyte differentiation.
Mu Y, Zhou H, Wu WJ, Hu LC, Chen HB
Molecular medicine reports 2015 Dec;12(6):8113-20
Molecular medicine reports 2015 Dec;12(6):8113-20
Cannabinoid WIN55, 212-2 induces cell cycle arrest and inhibits the proliferation and migration of human BEL7402 hepatocellular carcinoma cells.
Xu D, Wang J, Zhou Z, He Z, Zhao Q
Molecular medicine reports 2015 Dec;12(6):7963-70
Molecular medicine reports 2015 Dec;12(6):7963-70
miR-140-5p regulates adipocyte differentiation by targeting transforming growth factor-β signaling.
Zhang X, Chang A, Li Y, Gao Y, Wang H, Ma Z, Li X, Wang B
Scientific reports 2015 Dec 11;5:18118
Scientific reports 2015 Dec 11;5:18118
Quinolone-indolone conjugate induces apoptosis by inhibiting the EGFR-STAT3-HK2 pathway in human cancer cells.
Liu YH, Wei XL, Hu GQ, Wang TX
Molecular medicine reports 2015 Aug;12(2):2749-56
Molecular medicine reports 2015 Aug;12(2):2749-56
Postnatal alterations in GABAB receptor tone produce sensorimotor gating deficits and protein level differences in adulthood.
Bolton MM, Heaney CF, Murtishaw AS, Sabbagh JJ, Magcalas CM, Kinney JW
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2015 Apr;41:17-27
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2015 Apr;41:17-27
RAD51B Activity and Cell Cycle Regulation in Response to DNA Damage in Breast Cancer Cell Lines.
Lee PS, Fang J, Jessop L, Myers T, Raj P, Hu N, Wang C, Taylor PR, Wang J, Khan J, Jasin M, Chanock SJ
Breast cancer : basic and clinical research 2014;8:135-44
Breast cancer : basic and clinical research 2014;8:135-44
Inhibition of 15-lipoxygenase (15-LOX) reverses hypoxia-induced down-regulation of potassium channels Kv1.5 and Kv2.1Inhibition of 15-lipoxygenase (15-LOX) reverses hypoxia-induced down-regulation of potassium channels Kv1.5 and Kv2.1.
Liu W, Wang D, Song K, Chen L, Zhu Y, Liu P, Zhu Y
International journal of clinical and experimental medicine 2014;7(11):4147-53
International journal of clinical and experimental medicine 2014;7(11):4147-53
USP22 promotes the G1/S phase transition by upregulating FoxM1 expression via β-catenin nuclear localization and is associated with poor prognosis in stage II pancreatic ductal adenocarcinoma.
Ning Z, Wang A, Liang J, Xie Y, Liu J, Feng L, Yan Q, Wang Z
International journal of oncology 2014 Oct;45(4):1594-608
International journal of oncology 2014 Oct;45(4):1594-608
Role of α-lipoic acid in LPS/d-GalN induced fulminant hepatic failure in mice: studies on oxidative stress, inflammation and apoptosis.
Xia X, Su C, Fu J, Zhang P, Jiang X, Xu D, Hu L, Song E, Song Y
International immunopharmacology 2014 Oct;22(2):293-302
International immunopharmacology 2014 Oct;22(2):293-302
Identification and validation of a novel microRNA-like molecule derived from a cytoplasmic RNA virus antigenome by bioinformatics and experimental approaches.
Shi J, Duan Z, Sun J, Wu M, Wang B, Zhang J, Wang H, Hu N, Hu Y
Virology journal 2014 Jul 1;11:121
Virology journal 2014 Jul 1;11:121
Edwardsiella tarda-Induced cytotoxicity depends on its type III secretion system and flagellin.
Xie HX, Lu JF, Rolhion N, Holden DW, Nie P, Zhou Y, Yu XJ
Infection and immunity 2014 Aug;82(8):3436-45
Infection and immunity 2014 Aug;82(8):3436-45
Integrative genomics in combination with RNA interference identifies prognostic and functionally relevant gene targets for oral squamous cell carcinoma.
Xu C, Wang P, Liu Y, Zhang Y, Fan W, Upton MP, Lohavanichbutr P, Houck JR, Doody DR, Futran ND, Zhao LP, Schwartz SM, Chen C, Méndez E
PLoS genetics 2013;9(1):e1003169
PLoS genetics 2013;9(1):e1003169
Calpain mediates caspase-dependent apoptosis initiated by hydrogen peroxide in pancreatic acinar AR42J cells.
Weber H, Müller L, Jonas L, Schult C, Sparmann G, Schuff-Werner P
Free radical research 2013 May;47(5):432-46
Free radical research 2013 May;47(5):432-46
The hepatitis B virus X protein downregulates NF-κB signaling pathways through decreasing the Notch signaling pathway in HBx-transformed L02 cells.
Luo J, Zhou H, Wang F, Xia X, Sun Q, Wang R, Cheng B
International journal of oncology 2013 May;42(5):1636-43
International journal of oncology 2013 May;42(5):1636-43
Limb-girdle muscular dystrophy 1F is caused by a microdeletion in the transportin 3 gene.
Melià MJ, Kubota A, Ortolano S, Vílchez JJ, Gámez J, Tanji K, Bonilla E, Palenzuela L, Fernández-Cadenas I, Pristoupilová A, García-Arumí E, Andreu AL, Navarro C, Hirano M, Martí R
Brain : a journal of neurology 2013 May;136(Pt 5):1508-17
Brain : a journal of neurology 2013 May;136(Pt 5):1508-17
Cytohesin-2 as a novel prognostic marker for hepatocellular carcinoma.
Xu K, Gao J, Yang X, Yao Y, Liu Q
Oncology reports 2013 Jun;29(6):2211-8
Oncology reports 2013 Jun;29(6):2211-8
Roles of 3,4-methylenedioxymethamphetamine (MDMA)-induced alteration of connexin43 and intracellular Ca(2+) oscillation in its cardiotoxicity.
Zhuo L, Liu Q, Liu L, Sun TY, Wang RS, Qu GQ, Liu Q, Liu Y, Ren L
Toxicology 2013 Aug 9;310:61-72
Toxicology 2013 Aug 9;310:61-72
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The beta actin antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human beta actin. This antibody recognizes human,mouse,rat,zebrafish, monkey antigen. The beta actin antibody has been validated for the following applications: ELISA, IF, WB, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using ACTB antibody 20536-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon using 20536-1-AP(ACTB antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon using 20536-1-AP(ACTB antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
