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antibody from Novus Biologicals
Targeting: ACTB
Western blot
ELISA Immunocytochemistry Immunoprecipitation Immunohistochemistry Flow cytometry Chromatin ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [393]
- Comments [0]
- Validations
- Western blot [14]
- Immunohistochemistry [1]
- Flow cytometry [1]
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- Product number
- NB600-501 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB600-501, RRID:AB_10077656
- Product name
- Mouse Monoclonal beta-Actin Antibody
- Antibody type
- Monoclonal
- Description
- Unpurified. In staining of chicken gizzard ultrathin tissue cryosections, the antibody labels the dense bodies and longitudinal channels linking consecutive dense bodies that are also occupied by desmin and the membrane-associated dense plaque. It does not stain adult cardiac and skeletal muscles except for traces due to contaminations of the sample with non-muscle cells, or if embryonic tissue is being used. The epitope recognized by the antibody is resistant to formalin-fixing and paraffin-embedding.
- Reactivity
- Human, Mouse, Rat, Bovine, Canine, Chicken/Avian, Drosophila, Feline, Guinea Pig, Hamster, Porcine, Rabbit, Sheep, Simian, Zebrafish
- Host
- Mouse
- Antigen sequence
N-terminus of the beta isoform of a
ctin.- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references The Small GTPases Rab27b Regulates Mitochondrial Fatty Acid Oxidative Metabolism of Cardiac Mesenchymal Stem Cells.
THP-1 macrophage cholesterol efflux is impaired by palmitoleate through Akt activation.
Molecular profiling reveals a hypoxia signature in breast implant-associated anaplastic large cell lymphoma.
Retinoids Repress Human Cardiovascular Cell Calcification With Evidence for Distinct Selective Retinoid Modulator Effects.
High fat diet consumption results in mitochondrial dysfunction, oxidative stress, and oligodendrocyte loss in the central nervous system.
Local delivery of cardiac stem cells overexpressing HIF-1α promotes angiogenesis and muscular tissue repair in a hind limb ischemia model.
Myofibroblast contraction is essential for generating and regenerating the gas-exchange surface.
Inhibiting cellular uptake of mutant huntingtin using a monoclonal antibody: Implications for the treatment of Huntington's disease.
Cell-type-specific regulation of neuronal intrinsic excitability by macroautophagy.
Macrophage miR-34a Is a Key Regulator of Cholesterol Efflux and Atherosclerosis.
Multiorgan Systems Study Reveals Igfbp7 as a Suppressor of Gluconeogenesis after Gastric Bypass Surgery.
Chronic ethanol exposure alters prelimbic prefrontal cortical Fast-Spiking and Martinotti interneuron function with differential sex specificity in rat brain.
Gypenosides mediate cholesterol efflux and suppress oxidized LDL induced inflammation in retinal pigment epithelium cells.
Enhanced Anticancer Effect of Adding Magnesium to Vitamin C Therapy: Inhibition of Hormetic Response by SVCT-2 Activation.
Impacts of Intralipid on Nanodrug Abraxane Therapy and on the Innate Immune System.
Ursolic acid promotes apoptosis, autophagy, and chemosensitivity in gemcitabine-resistant human pancreatic cancer cells.
Modulating effect of Coronarin D in 5-fluorouracil resistance human oral cancer cell lines induced apoptosis and cell cycle arrest through JNK1/2 signaling pathway.
Systemic long-term inactivation of hypoxia-inducible factor prolyl 4-hydroxylase 2 ameliorates aging-induced changes in mice without affecting their life span.
Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance.
Angelica sinensis extract protects against ischemia-reperfusion injury in the hippocampus by activating p38 MAPK-mediated p90RSK/p-Bad and p90RSK/CREB/BDNF signaling after transient global cerebral ischemia in rats.
PBA Preferentially Impairs Cell Survival of Glioblastomas Carrying mutp53 by Reducing Its Expression Level, Stabilizing wtp53, Downregulating the Mevalonate Kinase and Dysregulating UPR.
Melanocortin-1 Receptor Positively Regulates Human Artery Endothelial Cell Migration.
Ferulic Acid Exerts Anti-apoptotic Effects against Ischemic Injury by Activating HSP70/Bcl-2- and HSP70/Autophagy-Mediated Signaling after Permanent Focal Cerebral Ischemia in Rats.
Endothelial Protein C Receptor Could Contribute to Experimental Malaria-Associated Acute Respiratory Distress Syndrome.
Plasmodium falciparum infection dysregulates placental autophagy.
MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition.
Cilostazol inhibits hyperglucose-induced vascular smooth muscle cell dysfunction by modulating the RAGE/ERK/NF-κB signaling pathways.
ANKRD9 is a metabolically-controlled regulator of IMPDH2 abundance and macro-assembly.
Formononetin Upregulates Nrf2/HO-1 Signaling and Prevents Oxidative Stress, Inflammation, and Kidney Injury in Methotrexate-Induced Rats.
CtIP is essential for telomere replication.
A mechanism in agrin signaling revealed by a prevalent Rapsyn mutation in congenital myasthenic syndrome.
Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites.
'Stemness' and 'senescence' related escape pathways are dose dependent in lung cancer cells surviving post irradiation.
Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing.
Mutations in KARS cause a severe neurological and neurosensory disease with optic neuropathy.
PTPN3 suppresses lung cancer cell invasiveness by counteracting Src-mediated DAAM1 activation and actin polymerization.
The Inability of the Choroid to Revascularize in Oxygen-Induced Retinopathy Results from Increased p53/miR-Let-7b Activity.
RNAase III-Type Enzyme Dicer Regulates Mitochondrial Fatty Acid Oxidative Metabolism in Cardiac Mesenchymal Stem Cells.
Chronic Ethanol Exposure and Withdrawal Impair Synaptic GABAA Receptor-Mediated Neurotransmission in Deep-Layer Prefrontal Cortex.
Lack of Myosin X Enhances Osteoclastogenesis and Increases Cell Surface Unc5b in Osteoclast-Lineage Cells.
Evidence for a Novel Regulatory Interaction Involving Cyclin D1, Lipid Droplets, Lipolysis, and Cell Cycle Progression in Hepatocytes.
Efficacy of leukemia inhibitory factor as a therapeutic for permanent large vessel stroke differs among aged male and female rats.
H727 cells are inherently resistant to the proteasome inhibitor carfilzomib, yet require proteasome activity for cell survival and growth.
Long Noncoding RNA ELIT-1 Acts as a Smad3 Cofactor to Facilitate TGFβ/Smad Signaling and Promote Epithelial-Mesenchymal Transition.
Phenethyl isothiocyanate stimulates glucose uptake through the Akt pathway in C2C12 myotubes.
Induced Chromosomal Aneuploidy Results in Global and Consistent Deregulation of the Transcriptome of Cancer Cells.
Magmas inhibition as a potential treatment strategy in malignant glioma.
Autophagy inhibition of cancer stem cells promotes the efficacy of cisplatin against non-small cell lung carcinoma.
Novel STAT3 Inhibitor LDOC1 Targets Phospho-JAK2 for Degradation by Interacting with LNX1 and Regulates the Aggressiveness of Lung Cancer.
Differential anti-tumour effects of MTH1 inhibitors in patient-derived 3D colorectal cancer cultures.
In vivo proximity proteomics of nascent synapses reveals a novel regulator of cytoskeleton-mediated synaptic maturation.
DLIC1, but not DLIC2, is upregulated in colon cancer and this contributes to proliferative overgrowth and migratory characteristics of cancer cells.
Novel Compound Heterozygote Mutation in IL10RA in a Patient With Very Early-Onset Inflammatory Bowel Disease.
Diurnal Rhythms Spatially and Temporally Organize Autophagy.
Prostate Tumor Cell-Derived IL1β Induces an Inflammatory Phenotype in Bone Marrow Adipocytes and Reduces Sensitivity to Docetaxel via Lipolysis-Dependent Mechanisms.
Repurposing Itraconazole Loaded PLGA Nanoparticles for Improved Antitumor Efficacy in Non-Small Cell Lung Cancers.
Nerve regeneration in rat peripheral nerve allografts: Evaluation of cold-inducible RNA-binding protein in nerve storage and regeneration.
Semaphorin 4A acts in a feed-forward loop with NF-κB pathway to exacerbate catabolic effect of IL-1β on chondrocytes.
Neuroprotective activity of leukemia inhibitory factor is relayed through myeloid zinc finger-1 in a rat model of stroke.
Systemic inactivation of hypoxia-inducible factor prolyl 4-hydroxylase 2 in mice protects from alcohol-induced fatty liver disease.
β1 Syntrophin Supports Autophagy Initiation and Protects against Cerulein-Induced Acute Pancreatitis.
Modulation of the ATM/autophagy pathway by a G-quadruplex ligand tips the balance between senescence and apoptosis in cancer cells.
Modified Sijunzi decoction can alleviate cisplatin-induced toxicity and prolong the survival time of cachectic mice by recovering muscle atrophy.
Biological effects of whole Z.Officinale extract on chronic myeloid leukemia cell line K562.
Hypercapnic and Hypoxic Respiratory Response During Wakefulness and Sleep in a Streptozotocin Model of Alzheimer's Disease in Rats.
The activation of G protein-coupled estrogen receptor induces relaxation via cAMP as well as potentiates contraction via EGFR transactivation in porcine coronary arteries.
Activation of spinal dorsal horn P2Y13 receptors can promote the expression of IL-1β and IL-6 in rats with diabetic neuropathic pain.
Suppression of m(6)A reader Ythdf2 promotes hematopoietic stem cell expansion.
Positional integration of lung adenocarcinoma susceptibility loci with primary human alveolar epithelial cell epigenomes.
Caspase-11 auto-proteolysis is crucial for noncanonical inflammasome activation.
Cancer-associated 2-oxoglutarate analogues modify histone methylation by inhibiting histone lysine demethylases.
Thermoregulatory profile of neurodegeneration-induced dementia of the Alzheimer's type using intracerebroventricular streptozotocin in rats.
Feedback control of the CXCR7/CXCL11 chemokine axis by estrogen receptor α in ovarian cancer.
Quantitative Proteomic Profiling Reveals Key Pathways in the Anticancer Action of Methoxychalcone Derivatives in Triple Negative Breast Cancer.
Leukemia inhibitory factor modulates the peripheral immune response in a rat model of emergent large vessel occlusion.
Context-enriched interactome powered by proteomics helps the identification of novel regulators of macrophage activation.
Sarcoglycan Alpha Mitigates Neuromuscular Junction Decline in Aged Mice by Stabilizing LRP4.
Endothelial Cell-Specific Inactivation of TSPAN12 (Tetraspanin 12) Reveals Pathological Consequences of Barrier Defects in an Otherwise Intact Vasculature.
Novel AR-12 derivatives, P12-23 and P12-34, inhibit flavivirus replication by blocking host de novo pyrimidine biosynthesis.
Reduced AMPK activation and increased HCAR activation drive anti-inflammatory response and neuroprotection in glaucoma.
Comparative immunohistochemical characterization of interstitial cells in the urinary bladder of human, guinea pig and pig.
Dimerization of sortilin regulates its trafficking to extracellular vesicles.
Intracellular lipid metabolism impairs β cell compensation during diet-induced obesity.
Kaempferol protects against propacetamol-induced acute liver injury through CYP2E1 inactivation, UGT1A1 activation, and attenuation of oxidative stress, inflammation and apoptosis in mice.
Inhibition of Japanese encephalitis virus infection by the host zinc-finger antiviral protein.
Characterization and use of the novel human multiple myeloma cell line MC-B11/14 to study biological consequences of CRISPR-mediated loss of immunoglobulin A heavy chain.
Mutations in SELENBP1, encoding a novel human methanethiol oxidase, cause extraoral halitosis.
VEGF secreted by mesenchymal stem cells mediates the differentiation of endothelial progenitor cells into endothelial cells via paracrine mechanisms.
Clemastine rescues myelination defects and promotes functional recovery in hypoxic brain injury.
Antrodia cinnamomea reduces obesity and modulates the gut microbiota in high-fat diet-fed mice.
Triple Vectors Expand AAV Transfer Capacity in the Retina.
ASC- and caspase-8-dependent apoptotic pathway diverges from the NLRC4 inflammasome in macrophages.
Quantitatively Predictable Control of Cellular Protein Levels through Proteasomal Degradation.
Pyruvate dehydrogenase complex and lactate dehydrogenase are targets for therapy of acute liver failure.
High-Throughput Screening Identifies Kinase Inhibitors That Increase Dual Adeno-Associated Viral Vector Transduction In Vitro and in Mouse Retina.
Intrahepatic hepatitis B virus large surface antigen induces hepatocyte hyperploidy via failure of cytokinesis.
Dopamine Triggers the Maturation of Striatal Spiny Projection Neuron Excitability during a Critical Period.
Identification and characterization of a novel chemically induced allele at the planar cell polarity gene Vangl2.
Effects of Electroacupuncture on Methamphetamine-Induced Behavioral Changes in Mice.
Astrocyte heterogeneity across the brain and spinal cord occurs developmentally, in adulthood and in response to demyelination.
Characterization of a panel of monoclonal antibodies recognizing specific epitopes on GFAP.
Oxidative stress and expression of insulin signaling proteins in the brain of diabetic rats: Role of Nigella sativa oil and antidiabetic drugs.
Attenuation of the Infiltration of Angiotensin II Expressing CD3+ T-Cells and the Modulation of Nerve Growth Factor in Lumbar Dorsal Root Ganglia - A Possible Mechanism Underpinning Analgesia Produced by EMA300, An Angiotensin II Type 2 (AT2) Receptor Antagonist.
Novel role of surfactant protein A in bacterial sinusitis.
Activation of dorsal horn cannabinoid CB2 receptor suppresses the expression of P2Y12 and P2Y13 receptors in neuropathic pain rats.
Fatty acid-binding protein 4 regulates fatty infiltration after rotator cuff tear by hypoxia-inducible factor 1 in mice.
Ethanol Exposure Regulates Gabra1 Expression via Histone Deacetylation at the Promoter in Cultured Cortical Neurons.
Downregulation of DNA repair proteins and increased DNA damage in hypoxic colon cancer cells is a therapeutically exploitable vulnerability.
Phenethyl isothiocyanate protects against H2O2-induced insulin resistance in 3T3-L1 adipocytes.
Study of poly-ɛ-caprolactone membranes for pleurodesis.
CD95 ligand induces senescence in mismatch repair-deficient human colon cancer via chronic caspase-mediated induction of DNA damage.
Differential effect of hypoxia and acidity on lung cancer cell and fibroblast metabolism.
Expression of p63 protein in anaplastic large cell lymphoma: implications for genetic subtyping.
Early Passage Mesenchymal Stem Cells Display Decreased Radiosensitivity and Increased DNA Repair Activity.
The Effects of Selected Sesquiterpenes from Myrica rubra Essential Oil on the Efficacy of Doxorubicin in Sensitive and Resistant Cancer Cell Lines.
A CK2-RNF4 interplay coordinates non-canonical SUMOylation and degradation of nuclear receptor FXR.
Down-regulation of hepatocyte nuclear factor-4α and defective zonation in livers expressing mutant Z α1-antitrypsin.
Leukemia Inhibitory Factor Protects Neurons from Ischemic Damage via Upregulation of Superoxide Dismutase 3.
Pituitary sex hormones enhance the pro‑metastatic potential of human lung cancer cells by downregulating the intracellular expression of heme oxygenase‑1.
Endothelial SCUBE2 Interacts With VEGFR2 and Regulates VEGF-Induced Angiogenesis.
Efficient programming of human mesenchymal stem cell-derived hepatocytes by epigenetic regulations.
The green microalga Tetraselmis suecica reduces oxidative stress and induces repairing mechanisms in human cells.
DEPTOR is a direct NOTCH1 target that promotes cell proliferation and survival in T-cell leukemia.
Functional Roles of Acetylated Histone Marks at Mouse Meiotic Recombination Hot Spots.
Protease activated receptor 2 controls myelin development, resiliency and repair.
Stabilization of hypoxia inducible factor by cobalt chloride can alter renal epithelial transport.
Hypoxia-inducible factor prolyl-4-hydroxylase-1 is a convergent point in the reciprocal negative regulation of NF-κB and p53 signaling pathways.
The Wnt Inhibitor Apcdd1 Coordinates Vascular Remodeling and Barrier Maturation of Retinal Blood Vessels.
Involvement of mTOR-autophagy in the selection of primitive mesenchymal stem cells in chitosan film 3-dimensional culture.
SLC10A4 regulates IgE-mediated mast cell degranulation in vitro and mast cell-mediated reactions in vivo.
Retinoic acid receptor alpha drives cell cycle progression and is associated with increased sensitivity to retinoids in T-cell lymphoma.
Recurrence of Hyperoxaluria and Kidney Disease after Combined Intestine-Kidney Transplantation for Enteric Hyperoxaluria.
Association of Heme Oxygenase 1 with Lung Protection in Malaria-Associated ALI/ARDS.
The Microtubule-Associated Protein Tau and Its Relevance for Pancreatic Beta Cells.
MicroRNA-21 Increases Proliferation and Cisplatin Sensitivity of Osteosarcoma-Derived Cells.
Targeting the thrombin receptor modulates inflammation and astrogliosis to improve recovery after spinal cord injury.
Aberrant Subcellular Dynamics of Sigma-1 Receptor Mutants Underlying Neuromuscular Diseases.
Effects of a Sublethal and Transient Stress of the Endoplasmic Reticulum on the Mitochondrial Population.
Lack of P4H-TM in mice results in age-related retinal and renal alterations.
Farnesoid X receptor activation increases reverse cholesterol transport by modulating bile acid composition and cholesterol absorption in mice.
PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation.
The flavonoid apigenin reduces prostate cancer CD44(+) stem cell survival and migration through PI3K/Akt/NF-κB signaling.
Regulatory effects of the L-lysine metabolites, L-2-aminoadipic acid and L-pipecolic acid, on protein turnover in C2C12 myotubes.
DDR1 promotes E-cadherin stability via inhibition of integrin-β1-Src activation-mediated E-cadherin endocytosis.
Mitochondrial Lon is over-expressed in high-grade gliomas, and mediates hypoxic adaptation: potential role of Lon as a therapeutic target in glioma.
Scriptaid overcomes hypoxia-induced cisplatin resistance in both wild-type and mutant p53 lung cancer cells.
Inter-domain tagging implicates caveolin-1 in insulin receptor trafficking and Erk signaling bias in pancreatic beta-cells.
The small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alpha.
HIF-P4H-2 deficiency protects against skeletal muscle ischemia-reperfusion injury.
Diluted serum from calorie-restricted animals promotes mitochondrial β-cell adaptations and protect against glucolipotoxicity.
Chlamydia trachomatis utilizes the mammalian CLA1 lipid transporter to acquire host phosphatidylcholine essential for growth.
Ceramide Synthase 5 Is Essential to Maintain C16:0-Ceramide Pools and Contributes to the Development of Diet-induced Obesity.
αv Integrins combine with LC3 and atg5 to regulate Toll-like receptor signalling in B cells.
Oncogenic roles of carbonic anhydrase 8 in human osteosarcoma cells.
Differential regulation of synaptic and extrasynaptic α4 GABA(A) receptor populations by protein kinase A and protein kinase C in cultured cortical neurons.
mda-7/IL-24 Induces Cell Death in Neuroblastoma through a Novel Mechanism Involving AIF and ATM.
Genome-wide analysis of HIF-2α chromatin binding sites under normoxia in human bronchial epithelial cells (BEAS-2B) suggests its diverse functions.
Lauric acid can improve the sensitization of Cetuximab in KRAS/BRAF mutated colorectal cancer cells by retrievable microRNA-378 expression.
Amyloid-β suppresses AMP-activated protein kinase (AMPK) signaling and contributes to α-synuclein-induced cytotoxicity.
Aliskiren Reduces Hepatic steatosis and Epididymal Fat Mass and Increases Skeletal Muscle Insulin Sensitivity in High-Fat Diet-Fed Mice.
An ID2-dependent mechanism for VHL inactivation in cancer.
The carbonic anhydrase inhibitor methazolamide prevents amyloid beta-induced mitochondrial dysfunction and caspase activation protecting neuronal and glial cells in vitro and in the mouse brain.
A Comprehensive Map of CNS Transduction by Eight Recombinant Adeno-associated Virus Serotypes Upon Cerebrospinal Fluid Administration in Pigs.
Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes.
The human organic cation transporter OCT1 mediates high affinity uptake of the anticancer drug daunorubicin.
Choroidal Involution Is Associated with a Progressive Degeneration of the Outer Retinal Function in a Model of Retinopathy of Prematurity: Early Role for IL-1β.
Kallikrein-related peptidase 6 exacerbates disease in an autoimmune model of multiple sclerosis.
A single injection of gain-of-function mutant PCSK9 adeno-associated virus vector induces cardiovascular calcification in mice with no genetic modification.
Differential Effects of Variations at Codon 106 on Sprouty2 Functions in Lung Cancer-Derived Cells.
TFEB and TFE3 cooperate in the regulation of the innate immune response in activated macrophages.
Novel small molecules potentiate premature termination codon readthrough by aminoglycosides.
Interplay between exercise and dietary fat modulates myelinogenesis in the central nervous system.
Differential Activation of Innate Immune Pathways by Distinct Islet Amyloid Polypeptide (IAPP) Aggregates.
Sexually Dimorphic Expression of eGFP Transgene in the Akr1A1 Locus of Mouse Liver Regulated by Sex Hormone-Related Epigenetic Remodeling.
Usp9X Is Required for Lymphocyte Activation and Homeostasis through Its Control of ZAP70 Ubiquitination and PKCβ Kinase Activity.
Carboxylesterase 1 Is Regulated by Hepatocyte Nuclear Factor 4α and Protects Against Alcohol- and MCD diet-induced Liver Injury.
Programmed cell death 2 functions as a tumor suppressor in osteosarcoma.
Functional consequences of copy number variants in miscarriage.
Wnt pathway activation and ABCB1 expression account for attenuation of proteasome inhibitor-mediated apoptosis in multidrug-resistant cancer cells.
The Inhibition of Heat Shock Protein 90 Facilitates the Degradation of Poly-Alanine Expanded Poly (A) Binding Protein Nuclear 1 via the Carboxyl Terminus of Heat Shock Protein 70-Interacting Protein.
Autophagosome Proteins LC3A, LC3B and LC3C Have Distinct Subcellular Distribution Kinetics and Expression in Cancer Cell Lines.
Angiopoietin Like Protein 2 (ANGPTL2) Promotes Adipose Tissue Macrophage and T lymphocyte Accumulation and Leads to Insulin Resistance.
Activation of AMP-Activated Protein Kinase by Adenine Alleviates TNF-Alpha-Induced Inflammation in Human Umbilical Vein Endothelial Cells.
TRPA1 mediates the effects of hypothermia on the monocyte inflammatory response.
Overexpression of hypoxia-inducible factor prolyl hydoxylase-2 attenuates hypoxia-induced vascular endothelial growth factor expression in luteal cells.
Dietary L-Lysine Suppresses Autophagic Proteolysis and Stimulates Akt/mTOR Signaling in the Skeletal Muscle of Rats Fed a Low-Protein Diet.
Hydrogen-rich water attenuates amyloid β-induced cytotoxicity through upregulation of Sirt1-FoxO3a by stimulation of AMP-activated protein kinase in SK-N-MC cells.
Amiodarone as an autophagy promoter reduces liver injury and enhances liver regeneration and survival in mice after partial hepatectomy.
Genetic targeting of protease activated receptor 2 reduces inflammatory astrogliosis and improves recovery of function after spinal cord injury.
Expression and contribution of the HIF-1α/VEGF signaling pathway to luteal development and function in pregnant rats.
The thrombin receptor is a critical extracellular switch controlling myelination.
Disruption of CLPB is associated with congenital microcephaly, severe encephalopathy and 3-methylglutaconic aciduria.
Humic Acid Increases Amyloid β-Induced Cytotoxicity by Induction of ER Stress in Human SK-N-MC Neuronal Cells.
Myosin phosphatase isoforms and related transcripts in the pig coronary circulation and effects of exercise and chronic occlusion.
Japanese encephalitis virus nonstructural protein NS5 interacts with mitochondrial trifunctional protein and impairs fatty acid β-oxidation.
Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition.
The metastatic tumor antigen 1-transglutaminase-2 pathway is involved in self-limitation of monosodium urate crystal-induced inflammation by upregulating TGF-β1.
Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota.
A metabolic stress-inducible miR-34a-HNF4α pathway regulates lipid and lipoprotein metabolism.
The increased Sprouty4 expression in response to serum is transcriptionally controlled by Specific protein 1.
Contrast Ultrasound Imaging Does Not Affect Heat Shock Protein 70 Expression in Cholesterol-Fed Rabbit Aorta.
Cardiomyocytes are Protected from Antiretroviral Nucleoside Analog-Induced Mitochondrial Toxicity by Overexpression of PGC-1α.
14-3-3ζ coordinates adipogenesis of visceral fat.
Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) Pathway Is Induced by Mechanical Load and Reduces the Activity of Hedgehog Signaling in Chondrogenic Micromass Cell Cultures.
IQGAP1 promotes CXCR4 chemokine receptor function and trafficking via EEA-1+ endosomes.
Soluble epoxide hydrolase activity regulates inflammatory responses and seizure generation in two mouse models of temporal lobe epilepsy.
Antrodan, a β-glucan obtained from Antrodia cinnamomea mycelia, is beneficial to benign prostate hyperplasia.
EGR1 supports the osteogenic differentiation of dental stem cells.
Antimicrobial peptide GW-H1-induced apoptosis of human gastric cancer AGS cell line is enhanced by suppression of autophagy.
Up-regulation of nicotinamide phosphoribosyltransferase and increase of NAD+ levels by glucose restriction extend replicative lifespan of human fibroblast Hs68 cells.
Attenuation of autophagic-proteolysis in C2C12 cells by saccharopine.
Plakophilin 1-deficient cells upregulate SPOCK1: implications for prostate cancer progression.
Carbonic anhydrase IX overexpression regulates the migration and progression in oral squamous cell carcinoma.
SYK is a target of lymphocyte-derived microparticles in the induction of apoptosis of human retinoblastoma cells.
Dengue Virus Impairs Mitochondrial Fusion by Cleaving Mitofusins.
β-Cell Insulin Secretion Requires the Ubiquitin Ligase COP1.
The AKT signaling pathway sustains the osteogenic differentiation in human dental follicle cells.
Photodynamic therapy using talaporfin sodium induces concentration-dependent programmed necroptosis in human glioblastoma T98G cells.
Exploring MicroRNA Expression Profiles Related to the mTOR Signaling Pathway in Mouse Embryonic Fibroblast Cells Treated with Polyethylenimine.
α-Naphthoflavone Increases Lipid Accumulation in Mature Adipocytes and Enhances Adipocyte-Stimulated Endothelial Tube Formation.
Characterization of the enhanced apoptotic response to azidothymidine by pharmacological inhibition of NF-kB.
Up-regulation of microRNA-190b plays a role for decreased IGF-1 that induces insulin resistance in human hepatocellular carcinoma.
High level of plasma matrix metalloproteinase-11 is associated with clinicopathological characteristics in patients with oral squamous cell carcinoma.
Androgen suppresses the proliferation of androgen receptor-positive castration-resistant prostate cancer cells via inhibition of Cdk2, CyclinA, and Skp2.
Photodynamic therapy with 5-aminolevulinic acid (ALA) impairs tumor initiating and chemo-resistance property in head and neck cancer-derived cancer stem cells.
Development of an experimental model to assess the bioavailability of zinc in practical piglet diets.
Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation.
Chalcone derivatives inhibit human platelet aggregation and inhibit growth in human bladder cancer cells.
Chalcone derivatives inhibit human platelet aggregation and inhibit growth in human bladder cancer cells.
Amelioration of LPS-induced inflammation response in microglia by AMPK activation.
4-phenylbutyric acid attenuates endoplasmic reticulum stress-mediated pancreatic β-cell apoptosis in rats with streptozotocin-induced diabetes.
Hibernation alters the diversity and composition of mucosa-associated bacteria while enhancing antimicrobial defence in the gut of 13-lined ground squirrels.
MicroRNA-205 targets tight junction-related proteins during urothelial cellular differentiation.
Regulation of proximal T cell receptor signaling and tolerance induction by deubiquitinase Usp9X.
Autophagy-related gene expression analysis of wild-type and atg5 gene knockout mouse embryonic fibroblast cells treated with polyethylenimine.
HIF prolyl 4-hydroxylase-2 inhibition improves glucose and lipid metabolism and protects against obesity and metabolic dysfunction.
Anti-cancer effects of ursane triterpenoid as a single agent and in combination with cisplatin in bladder cancer.
Homologous recombination repair signaling in chemical carcinogenesis: prolonged particulate hexavalent chromium exposure suppresses the Rad51 response in human lung cells.
Effects of insulin on human pancreatic cancer progression modeled in vitro.
Hepatic carboxylesterase 1 is essential for both normal and farnesoid X receptor-controlled lipid homeostasis.
Electrophysiological characterization of spinal neuron sensitization by elevated calcium channel alpha-2-delta-1 subunit protein.
Tempol protects cardiomyocytes from nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity.
4-Phenylbutyric acid suppresses inflammation through regulation of endoplasmic reticulum stress of endothelial cells stimulated by uremic serum.
Mechanism of action for the cytotoxic effects of the nitric oxide prodrug JS-K in murine erythroleukemia cells.
Regulation by resveratrol of the cellular factors mediating liver damage and regeneration after acute toxic liver injury.
Calcium channel α2δ1 proteins mediate trigeminal neuropathic pain states associated with aberrant excitatory synaptogenesis.
H3K4me3 breadth is linked to cell identity and transcriptional consistency.
Human cytomegalovirus immediate early proteins promote degradation of connexin 43 and disrupt gap junction communication: implications for a role in gliomagenesis.
In non-small cell lung cancer mitogenic signaling leaves Sprouty1 protein levels unaffected.
Permanent activation of HMGA2 in lipomas mimics its temporal physiological activation linked to the gain of adipose tissue.
NOTCH1 signaling regulates the BMP2/DLX-3 directed osteogenic differentiation of dental follicle cells.
Primary macrophages rely on histone deacetylase 1 and 2 expression to induce type I interferon in response to gammaherpesvirus infection.
High prevalence of human cytomegalovirus in brain metastases of patients with primary breast and colorectal cancers.
Hibernation induces immune changes in the lung of 13-lined ground squirrels (Ictidomys tridecemlineatus).
Profiling Hsp90 differential expression and the molecular effects of the Hsp90 inhibitor IPI-504 in high-grade glioma models.
RB maintains quiescence and prevents premature senescence through upregulation of DNMT1 in mesenchymal stromal cells.
Dual disruption of DNA repair and telomere maintenance for the treatment of head and neck cancer.
Plakophilins 1 and 3 bind to FXR1 and thereby influence the mRNA stability of desmosomal proteins.
TPX2 expression is associated with cell proliferation and patient outcome in esophageal squamous cell carcinoma.
Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis.
Surfactant-modified nanoclay exhibits an antiviral activity with high potency and broad spectrum.
Hypoxia after liver surgery imposes an aggressive cancer stem cell phenotype on residual tumor cells.
Trigeminal nerve injury-induced thrombospondin-4 up-regulation contributes to orofacial neuropathic pain states in a rat model.
Leptin deficiency in rats results in hyperinsulinemia and impaired glucose homeostasis.
Rapid degradation of the complement regulator, CD59, by a novel inhibitor.
Eosinophils regulate peripheral B cell numbers in both mice and humans.
Novel mutations in Lrp6 orthologs in mouse and human neural tube defects affect a highly dosage-sensitive Wnt non-canonical planar cell polarity pathway.
Reappraisal of the therapeutic role of celecoxib in cholangiocarcinoma.
Difference in protein expression profile and chemotherapy drugs response of different progression stages of LNCaP sublines and other human prostate cancer cells.
Harnessing gene conversion in chicken B cells to create a human antibody sequence repertoire.
Phosphatidylinositol-3-phosphate regulates sorting and processing of amyloid precursor protein through the endosomal system.
Hirsutella sinensis mycelium suppresses interleukin-1β and interleukin-18 secretion by inhibiting both canonical and non-canonical inflammasomes.
Integrin binding and MAPK signal pathways in primary cell responses to surface chemistry of calcium silicate cements.
Maspin is a marker for early recurrence in primary stage III and IV colorectal cancer.
Palmitate induces transcriptional regulation of BACE1 and presenilin by STAT3 in neurons mediated by astrocytes.
IMP1 promotes choriocarcinoma cell migration and invasion through the novel effectors RSK2 and PPME1.
Kallikrein 6 signals through PAR1 and PAR2 to promote neuron injury and exacerbate glutamate neurotoxicity.
The secretome of colon cancer stem cells contains drug-metabolizing enzymes.
The mTOR kinase inhibitors, CC214-1 and CC214-2, preferentially block the growth of EGFRvIII-activated glioblastomas.
Inhibition of high-mobility group box 1 in lung reduced airway inflammation and remodeling in a mouse model of chronic asthma.
Novel TRAF1-ALK fusion identified by deep RNA sequencing of anaplastic large cell lymphoma.
Thrombospondin-4 contributes to spinal cord injury-induced changes in nociception.
Induction of hepatocyte-like cells from mouse embryonic stem cells by lentivirus-mediated constitutive expression of Foxa2/Hnf4a.
Overexpression of caldesmon is associated with lymph node metastasis and poorer prognosis in patients with oral cavity squamous cell carcinoma.
Quercetin in elimination of tumor initiating stem-like and mesenchymal transformation property in head and neck cancer.
Clinical significance and novel mechanism of action of kallikrein 6 in glioblastoma.
Macrophage cathepsin K promotes prostate tumor progression in bone.
Cuttlefish skin papilla morphology suggests a muscular hydrostatic function for rapid changeability.
Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain.
EGFR mutation-induced alternative splicing of Max contributes to growth of glycolytic tumors in brain cancer.
Glucocorticoids alleviate intestinal ER stress by enhancing protein folding and degradation of misfolded proteins.
Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells.
Phenotypic and functional consequences of haploinsufficiency of genes from exocyst and retinoic acid pathway due to a recurrent microdeletion of 2p13.2.
Mutations in SYNGAP1 cause intellectual disability, autism, and a specific form of epilepsy by inducing haploinsufficiency.
Unsaturated fatty acids and phytosterols regulate cholesterol transporter genes in Caco-2 and HepG2 cell lines.
Exercise training-enhanced, endothelium-dependent dilation mediated by altered regulation of BK(Ca) channels in collateral-dependent porcine coronary arterioles.
Cleome arabica leaf extract has anticancer properties in human cancer cells.
Aip regulates cAMP signalling and GH secretion in GH3 cells.
CXCR4 chemokine receptor signaling induces apoptosis in acute myeloid leukemia cells via regulation of the Bcl-2 family members Bcl-XL, Noxa, and Bak.
Differential proteomic analysis of cancer stem cell properties in hepatocellular carcinomas by isobaric tag labeling and mass spectrometry.
Sprouty2 but not Sprouty4 is a potent inhibitor of cell proliferation and migration of osteosarcoma cells.
PROTAC-induced proteolytic targeting.
Suppression of extensive neurofilament phosphorylation rescues α-Internexin/peripherin-overexpressing PC12 cells from neuronal cell death.
Novel insights into the distribution and functional aspects of the calcium binding protein secretagogin from studies on rat brain and primary neuronal cell culture.
Low-level laser therapy alleviates neuropathic pain and promotes function recovery in rats with chronic constriction injury: possible involvements in hypoxia-inducible factor 1α (HIF-1α).
Hypoxia-inducible factor-1 (HIF-1) but not HIF-2 is essential for hypoxic induction of collagen prolyl 4-hydroxylases in primary newborn mouse epiphyseal growth plate chondrocytes.
Mechanisms of prostate permeability triggered by microbubble-mediated acoustic cavitation.
Functional and histological outcome after focal traumatic brain injury is not improved in conditional EphA4 knockout mice.
Obesity and weight loss result in increased adipose tissue ABCG1 expression in db/db mice.
Angiotensin II induces extracellular matrix metalloproteinase inducer expression via an AT1R dependent pathway in aortic atherosclerotic plaque in apolipoprotein E knockout mice.
A selective inhibitor of the immunoproteasome subunit LMP2 induces apoptosis in PC-3 cells and suppresses tumour growth in nude mice.
Methylation by Set9 modulates FoxO3 stability and transcriptional activity.
β-Catenin gain of function in muscles impairs neuromuscular junction formation.
D(-)lentiginosine-induced apoptosis involves the intrinsic pathway and is p53-independent.
2,4,5-TMBA, a natural inhibitor of cyclooxygenase-2, suppresses adipogenesis and promotes lipolysis in 3T3-L1 adipocytes.
Unexpected gender difference in sensitivity to the acute toxicity of dioxin in mice.
Distinct roles of muscle and motoneuron LRP4 in neuromuscular junction formation.
A neuronal death model: overexpression of neuronal intermediate filament protein peripherin in PC12 cells.
Wnt proteins regulate acetylcholine receptor clustering in muscle cells.
Association of tumor-associated trypsin inhibitor (TATI) expression with molecular markers, pathologic features and clinical outcomes of urothelial carcinoma of the urinary bladder.
Protective role of autophagy in branched polyethylenimine (25K)- and poly(L-lysine) (30-70K)-induced cell death.
FoxO6 regulates memory consolidation and synaptic function.
Placental, renal, and ileal sulfate transporter gene expression in mouse gestation.
Retinoic acid promotes proliferation of chicken primordial germ cells via activation of PI3K/Akt-mediated NF-κB signalling cascade.
Effects of tirapazamine on experimental colorectal liver metastases after radiofrequency ablation.
Proteomics of post-traumatic proliferative vitreoretinopathy in rabbit retina reveals alterations to a variety of functional proteins.
Age-dependent decline of DNA base excision repair activity in rat cortical neurons.
The effect of 17{beta}-estradiol on cholesterol content in human macrophages is influenced by the lipoprotein milieu.
ABIN1 protein cooperates with TAX1BP1 and A20 proteins to inhibit antiviral signaling.
Musashi expression in β-cells coordinates insulin expression, apoptosis and proliferation in response to endoplasmic reticulum stress in diabetes.
COP1 is a tumour suppressor that causes degradation of ETS transcription factors.
Functional role of kallikrein 6 in regulating immune cell survival.
UBE2M-mediated p27(Kip1) degradation in gemcitabine cytotoxicity.
HDAC inhibitor 4-phenylbutyrate preserves immature phenotype of human embryonic midbrain stem cells: implications for the involvement of DNA methyltransferase.
Identification of the nanogold particle-induced endoplasmic reticulum stress by omic techniques and systems biology analysis.
19-Nor-2α-(3-hydroxypropyl)-1α,25-dihydroxyvitamin D3 (MART-10) is a potent cell growth regulator with enhanced chemotherapeutic potency in liver cancer cells.
Aldo-keto reductase 1B7 is a target gene of FXR and regulates lipid and glucose homeostasis.
Synergistic killing of colorectal cancer cells by oxaliplatin and ABT-737.
A role for CD95 signaling in ischemia/reperfusion-induced invasion and outgrowth of colorectal micrometastases in mouse liver.
Adipocyte expression of the glucose-dependent insulinotropic polypeptide receptor involves gene regulation by PPARγ and histone acetylation.
Chromatin immunoprecipitation to analyze DNA binding sites of HMGA2.
Kinetics and longevity of ΦC31 integrase in mouse liver and cultured cells.
Inhibition of the visual cycle by A2E through direct interaction with RPE65 and implications in Stargardt disease.
Enhanced anti-inflammatory activities of Monascus pilosus fermented products by addition of ginger to the medium.
A BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling.
The novel proapoptotic activity of nonnatural enantiomer of Lentiginosine.
A role for NRAGE in NF-kappaB activation through the non-canonical BMP pathway.
Oncogenic K-ras activates p38 to maintain colorectal cancer cell proliferation during MEK inhibition.
Effect of nuclear localization and hydrodynamic delivery-induced cell division on phiC31 integrase activity.
Involvement of VDAC1 and Bcl-2 family of proteins in VacA-induced cytochrome c release and apoptosis of gastric epithelial carcinoma cells.
Expression of TAU in insulin-secreting cells and its interaction with the calcium-binding protein secretagogin.
Oncogenic KRAS sensitises colorectal tumour cells to chemotherapy by p53-dependent induction of Noxa.
Neuropilin-1 is essential for enhanced VEGF(165)-mediated vasodilatation in collateral-dependent coronary arterioles of exercise-trained pigs.
Analysis of glycosyltransferase expression in metastatic prostate cancer cells capable of rolling activity on microvascular endothelial (E)-selectin.
HSP90 beta regulates rapsyn turnover and subsequent AChR cluster formation and maintenance.
LRP4 serves as a coreceptor of agrin.
Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis.
Inhibition of Raf-1 alters multiple downstream pathways to induce pancreatic beta-cell apoptosis.
CDDO-imidazolide mediated inhibition of malignant cell growth in Waldenström macroglobulinemia.
Glucose and endoplasmic reticulum calcium channels regulate HIF-1beta via presenilin in pancreatic beta-cells.
The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor.
Conditional neuronal simian virus 40 T antigen expression induces Alzheimer-like tau and amyloid pathology in mice.
Inhibition of glycogen synthase kinase-3 activity leads to epigenetic silencing of nuclear factor kappaB target genes and induction of apoptosis in chronic lymphocytic leukemia B cells.
OSU-03012, a novel celecoxib derivative, is cytotoxic to myeloma cells and acts through multiple mechanisms.
Effect of a vascular endothelial growth factor (VEGF) inhibitory treatment on the folliculogenesis and ovarian apoptosis in gonadotropin-treated prepubertal rats.
Interleukin-10 anti-inflammatory response to Borrelia burgdorferi, the agent of Lyme disease: a possible role for suppressors of cytokine signaling 1 and 3.
Sulindac independently modulates extracellular signal-regulated kinase 1/2 and cyclic GMP-dependent protein kinase signaling pathways.
Bone morphogenetic protein-2 induces proinflammatory endothelial phenotype.
Deficiency in the catalytic subunit of DNA-dependent protein kinase causes down-regulation of ATM.
Quantitative protein expression analysis of CLL B cells from mutated and unmutated IgV(H) subgroups using acid-cleavable isotope-coded affinity tag reagents.
Role of homologous recombination in the alpha-particle-induced bystander effect for sister chromatid exchanges and chromosomal aberrations.
Role of homologous recombination in the alpha-particle-induced bystander effect for sister chromatid exchanges and chromosomal aberrations.
RPE65 is the isomerohydrolase in the retinoid visual cycle.
Antinuclear antigen B cells that down-regulate surface B cell receptor during development to mature, follicular phenotype do not display features of anergy in vitro.
Antinuclear antigen B cells that down-regulate surface B cell receptor during development to mature, follicular phenotype do not display features of anergy in vitro.
Differential display polymerase chain reaction reveals increased expression of striatal rat glia-derived nexin following chronic clozapine treatment.
Involvement of raft-like plasma membrane domains of Entamoeba histolytica in pinocytosis and adhesion.
Oxidant stress in kidneys of spontaneously hypertensive rats involves both oxidase overexpression and loss of extracellular superoxide dismutase.
Degradation of NF-kappa B in T cells by gangliosides expressed on renal cell carcinomas.
Degradation of NF-kappa B in T cells by gangliosides expressed on renal cell carcinomas.
Inhibition of insulin synthesis by cyproheptadine: effects on translation.
Reduced release of nitric oxide to shear stress in mesenteric arteries of aged rats.
Oxidant stress leads to impaired regulation of renal cortical oxygen consumption by nitric oxide in the aging kidney.
Oxidant stress leads to impaired regulation of renal cortical oxygen consumption by nitric oxide in the aging kidney.
Modulation of nuclear factor-kappa B activity by indomethacin influences A beta levels but not A beta precursor protein metabolism in a model of Alzheimer's disease.
Modulation of nuclear factor-kappa B activity by indomethacin influences A beta levels but not A beta precursor protein metabolism in a model of Alzheimer's disease.
Imatinib mesylate inhibits T-cell proliferation in vitro and delayed-type hypersensitivity in vivo.
Antiangiogenic and proapoptotic effects of dietary restriction on experimental mouse and human brain tumors.
Genome-wide discovery of loci influencing chemotherapy cytotoxicity.
Direct reprobing with anti-beta-actin antibody as an internal control for western blotting analysis.
Beta-actin specific monoclonal antibody.
Actin isoform compartments in chicken gizzard smooth muscle cells.
Calponin is localised in both the contractile apparatus and the cytoskeleton of smooth muscle cells.
Jin Y, Shen Y, Su X, Cai J, Liu Y, Weintraub NL, Tang Y
Frontiers in cell and developmental biology 2020;8:209
Frontiers in cell and developmental biology 2020;8:209
THP-1 macrophage cholesterol efflux is impaired by palmitoleate through Akt activation.
Marshall JD, Courage ER, Elliott RF, Fitzpatrick MN, Kim AD, Lopez-Clavijo AF, Woolfrey BA, Ouimet M, Wakelam MJO, Brown RJ
PloS one 2020;15(5):e0233180
PloS one 2020;15(5):e0233180
Molecular profiling reveals a hypoxia signature in breast implant-associated anaplastic large cell lymphoma.
Oishi N, Hundal T, Phillips JL, Dasari S, Hu G, Viswanatha DS, He R, Mai M, Jacobs HK, Ahmed NH, Syrbu SI, Salama Y, Chapman JR, Vega F, Sidhu J, Bennani NN, Epstein AL, Medeiros LJ, Clemens MW, Miranda RN, Feldman AL
Haematologica 2020 May 15;
Haematologica 2020 May 15;
Retinoids Repress Human Cardiovascular Cell Calcification With Evidence for Distinct Selective Retinoid Modulator Effects.
Rogers MA, Chen J, Nallamshetty S, Pham T, Goto S, Muehlschlegel JD, Libby P, Aikawa M, Aikawa E, Plutzky J
Arteriosclerosis, thrombosis, and vascular biology 2020 Mar;40(3):656-669
Arteriosclerosis, thrombosis, and vascular biology 2020 Mar;40(3):656-669
High fat diet consumption results in mitochondrial dysfunction, oxidative stress, and oligodendrocyte loss in the central nervous system.
Langley MR, Yoon H, Kim HN, Choi CI, Simon W, Kleppe L, Lanza IR, LeBrasseur NK, Matveyenko A, Scarisbrick IA
Biochimica et biophysica acta. Molecular basis of disease 2020 Mar 1;1866(3):165630
Biochimica et biophysica acta. Molecular basis of disease 2020 Mar 1;1866(3):165630
Local delivery of cardiac stem cells overexpressing HIF-1α promotes angiogenesis and muscular tissue repair in a hind limb ischemia model.
Pei X, Kim H, Lee M, Wang N, Shin J, Lee S, Yoon M, Yang VC, He H
Journal of controlled release : official journal of the Controlled Release Society 2020 Jun 10;322:610-621
Journal of controlled release : official journal of the Controlled Release Society 2020 Jun 10;322:610-621
Myofibroblast contraction is essential for generating and regenerating the gas-exchange surface.
Li R, Li X, Hagood J, Zhu MS, Sun X
The Journal of clinical investigation 2020 Jun 1;130(6):2859-2871
The Journal of clinical investigation 2020 Jun 1;130(6):2859-2871
Inhibiting cellular uptake of mutant huntingtin using a monoclonal antibody: Implications for the treatment of Huntington's disease.
Bartl S, Oueslati A, Southwell AL, Siddu A, Parth M, David LS, Maxan A, Salhat N, Burkert M, Mairhofer A, Friedrich T, Pankevych H, Balazs K, Staffler G, Hayden MR, Cicchetti F, Smrzka OW
Neurobiology of disease 2020 Jul;141:104943
Neurobiology of disease 2020 Jul;141:104943
Cell-type-specific regulation of neuronal intrinsic excitability by macroautophagy.
Lieberman OJ, Frier MD, McGuirt AF, Griffey CJ, Rafikian E, Yang M, Yamamoto A, Borgkvist A, Santini E, Sulzer D
eLife 2020 Jan 8;9
eLife 2020 Jan 8;9
Macrophage miR-34a Is a Key Regulator of Cholesterol Efflux and Atherosclerosis.
Xu Y, Xu Y, Zhu Y, Sun H, Juguilon C, Li F, Fan D, Yin L, Zhang Y
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Jan 8;28(1):202-216
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Jan 8;28(1):202-216
Multiorgan Systems Study Reveals Igfbp7 as a Suppressor of Gluconeogenesis after Gastric Bypass Surgery.
Arima N, Sasaki Y, Lee LH, Zhang H, Figueiredo JL, Mlynarchik AK, Qiao J, Yamada I, Higashi H, Ha AH, Halu A, Mizuno K, Singh SA, Yamazaki Y, Aikawa M
Journal of proteome research 2020 Jan 3;19(1):129-143
Journal of proteome research 2020 Jan 3;19(1):129-143
Chronic ethanol exposure alters prelimbic prefrontal cortical Fast-Spiking and Martinotti interneuron function with differential sex specificity in rat brain.
Hughes BA, Crofton EJ, O'Buckley TK, Herman MA, Morrow AL
Neuropharmacology 2020 Jan 1;162:107805
Neuropharmacology 2020 Jan 1;162:107805
Gypenosides mediate cholesterol efflux and suppress oxidized LDL induced inflammation in retinal pigment epithelium cells.
Biswas L, Zeng Z, Graham A, Shu X
Experimental eye research 2020 Feb;191:107931
Experimental eye research 2020 Feb;191:107931
Enhanced Anticancer Effect of Adding Magnesium to Vitamin C Therapy: Inhibition of Hormetic Response by SVCT-2 Activation.
Cho S, Chae JS, Shin H, Shin Y, Kim Y, Kil EJ, Byun HS, Cho SH, Park S, Lee S, Yeom CH
Translational oncology 2020 Feb;13(2):401-409
Translational oncology 2020 Feb;13(2):401-409
Impacts of Intralipid on Nanodrug Abraxane Therapy and on the Innate Immune System.
Chen YJ, Tsai CY, Cheng YM, Nieh SW, Yeh TK, Chen CP, Wang MH, Chou LH, Chiu TY, Liu L, Ho C, Chen CT, Liu TW
Scientific reports 2020 Feb 18;10(1):2838
Scientific reports 2020 Feb 18;10(1):2838
Ursolic acid promotes apoptosis, autophagy, and chemosensitivity in gemcitabine-resistant human pancreatic cancer cells.
Lin JH, Chen SY, Lu CC, Lin JA, Yen GC
Phytotherapy research : PTR 2020 Aug;34(8):2053-2066
Phytotherapy research : PTR 2020 Aug;34(8):2053-2066
Modulating effect of Coronarin D in 5-fluorouracil resistance human oral cancer cell lines induced apoptosis and cell cycle arrest through JNK1/2 signaling pathway.
Hsieh MY, Hsieh MJ, Lo YS, Lin CC, Chuang YC, Chen MK, Chou MC
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110318
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110318
Systemic long-term inactivation of hypoxia-inducible factor prolyl 4-hydroxylase 2 ameliorates aging-induced changes in mice without affecting their life span.
Laitakari A, Huttunen R, Kuvaja P, Hannuksela P, Szabo Z, Heikkilä M, Kerkelä R, Myllyharju J, Dimova EY, Serpi R, Koivunen P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Apr;34(4):5590-5609
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Apr;34(4):5590-5609
Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance.
Barbier V, Erbani J, Fiveash C, Davies JM, Tay J, Tallack MR, Lowe J, Magnani JL, Pattabiraman DR, Perkins AC, Lisle J, Rasko JEJ, Levesque JP, Winkler IG
Nature communications 2020 Apr 27;11(1):2042
Nature communications 2020 Apr 27;11(1):2042
Angelica sinensis extract protects against ischemia-reperfusion injury in the hippocampus by activating p38 MAPK-mediated p90RSK/p-Bad and p90RSK/CREB/BDNF signaling after transient global cerebral ischemia in rats.
Cheng CY, Kao ST, Lee YC
Journal of ethnopharmacology 2020 Apr 24;252:112612
Journal of ethnopharmacology 2020 Apr 24;252:112612
PBA Preferentially Impairs Cell Survival of Glioblastomas Carrying mutp53 by Reducing Its Expression Level, Stabilizing wtp53, Downregulating the Mevalonate Kinase and Dysregulating UPR.
Romeo MA, Gilardini Montani MS, Benedetti R, Garufi A, D'Orazi G, Cirone M
Biomolecules 2020 Apr 10;10(4)
Biomolecules 2020 Apr 10;10(4)
Melanocortin-1 Receptor Positively Regulates Human Artery Endothelial Cell Migration.
Saporiti F, Piacentini L, Alfieri V, Bono E, Ferrari F, Chiesa M, Colombo GI
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2019;52(6):1339-1360
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2019;52(6):1339-1360
Ferulic Acid Exerts Anti-apoptotic Effects against Ischemic Injury by Activating HSP70/Bcl-2- and HSP70/Autophagy-Mediated Signaling after Permanent Focal Cerebral Ischemia in Rats.
Cheng CY, Kao ST, Lee YC
The American journal of Chinese medicine 2019;47(1):39-61
The American journal of Chinese medicine 2019;47(1):39-61
Endothelial Protein C Receptor Could Contribute to Experimental Malaria-Associated Acute Respiratory Distress Syndrome.
Dos Santos Ortolan L, Sercundes MK, Moura GC, de Castro Quirino T, Debone D, de Sousa Costa D, Murillo O, Marinho CRF, Epiphanio S
Journal of immunology research 2019;2019:3105817
Journal of immunology research 2019;2019:3105817
Plasmodium falciparum infection dysregulates placental autophagy.
Lima FA, Barateiro A, Dombrowski JG, de Souza RM, Costa DS, Murillo O, Epiphanio S, Gonçalves LA, Marinho CRF
PloS one 2019;14(12):e0226117
PloS one 2019;14(12):e0226117
MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition.
Vande Walle L, Stowe IB, Šácha P, Lee BL, Demon D, Fossoul A, Van Hauwermeiren F, Saavedra PHV, Šimon P, Šubrt V, Kostka L, Stivala CE, Pham VC, Staben ST, Yamazoe S, Konvalinka J, Kayagaki N, Lamkanfi M
PLoS biology 2019 Sep;17(9):e3000354
PLoS biology 2019 Sep;17(9):e3000354
Cilostazol inhibits hyperglucose-induced vascular smooth muscle cell dysfunction by modulating the RAGE/ERK/NF-κB signaling pathways.
Su SC, Hung YJ, Huang CL, Shieh YS, Chien CY, Chiang CF, Liu JS, Lu CH, Hsieh CH, Lin CM, Lee CH
Journal of biomedical science 2019 Sep 6;26(1):68
Journal of biomedical science 2019 Sep 6;26(1):68
ANKRD9 is a metabolically-controlled regulator of IMPDH2 abundance and macro-assembly.
Hayward D, Kouznetsova VL, Pierson HE, Hasan NM, Guzman ER, Tsigelny IF, Lutsenko S
The Journal of biological chemistry 2019 Sep 27;294(39):14454-14466
The Journal of biological chemistry 2019 Sep 27;294(39):14454-14466
Formononetin Upregulates Nrf2/HO-1 Signaling and Prevents Oxidative Stress, Inflammation, and Kidney Injury in Methotrexate-Induced Rats.
Aladaileh SH, Hussein OE, Abukhalil MH, Saghir SAM, Bin-Jumah M, Alfwuaires MA, Germoush MO, Almaiman AA, Mahmoud AM
Antioxidants (Basel, Switzerland) 2019 Sep 26;8(10)
Antioxidants (Basel, Switzerland) 2019 Sep 26;8(10)
CtIP is essential for telomere replication.
Stroik S, Kurtz K, Hendrickson EA
Nucleic acids research 2019 Sep 26;47(17):8927-8940
Nucleic acids research 2019 Sep 26;47(17):8927-8940
A mechanism in agrin signaling revealed by a prevalent Rapsyn mutation in congenital myasthenic syndrome.
Xing G, Jing H, Zhang L, Cao Y, Li L, Zhao K, Dong Z, Chen W, Wang H, Cao R, Xiong WC, Mei L
eLife 2019 Sep 24;8
eLife 2019 Sep 24;8
Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites.
Holdgaard SG, Cianfanelli V, Pupo E, Lambrughi M, Lubas M, Nielsen JC, Eibes S, Maiani E, Harder LM, Wesch N, Foged MM, Maeda K, Nazio F, de la Ballina LR, Dötsch V, Brech A, Frankel LB, Jäättelä M, Locatelli F, Barisic M, Andersen JS, Bekker-Jensen S, Lund AH, Rogov VV, Papaleo E, Lanzetti L, De Zio D, Cecconi F
Nature communications 2019 Sep 13;10(1):4176
Nature communications 2019 Sep 13;10(1):4176
'Stemness' and 'senescence' related escape pathways are dose dependent in lung cancer cells surviving post irradiation.
Tsolou A, Lamprou I, Fortosi AO, Liousia M, Giatromanolaki A, Koukourakis MI
Life sciences 2019 Sep 1;232:116562
Life sciences 2019 Sep 1;232:116562
Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing.
Mahmoudi S, Mancini E, Xu L, Moore A, Jahanbani F, Hebestreit K, Srinivasan R, Li X, Devarajan K, Prélot L, Ang CE, Shibuya Y, Benayoun BA, Chang ALS, Wernig M, Wysocka J, Longaker MT, Snyder MP, Brunet A
Nature 2019 Oct;574(7779):553-558
Nature 2019 Oct;574(7779):553-558
Mutations in KARS cause a severe neurological and neurosensory disease with optic neuropathy.
Scheidecker S, Bär S, Stoetzel C, Geoffroy V, Lannes B, Rinaldi B, Fischer F, Becker HD, Pelletier V, Pagan C, Acquaviva-Bourdain C, Kremer S, Mirande M, Tranchant C, Muller J, Friant S, Dollfus H
Human mutation 2019 Oct;40(10):1826-1840
Human mutation 2019 Oct;40(10):1826-1840
PTPN3 suppresses lung cancer cell invasiveness by counteracting Src-mediated DAAM1 activation and actin polymerization.
Li MY, Peng WH, Wu CH, Chang YM, Lin YL, Chang GD, Wu HC, Chen GC
Oncogene 2019 Oct;38(44):7002-7016
Oncogene 2019 Oct;38(44):7002-7016
The Inability of the Choroid to Revascularize in Oxygen-Induced Retinopathy Results from Increased p53/miR-Let-7b Activity.
Zhou TE, Zhu T, Rivera JC, Omri S, Tahiri H, Lahaie I, Rouget R, Wirth M, Nattel S, Lodygensky G, Ferbeyre G, Nezhady M, Desjarlais M, Hamel P, Chemtob S
The American journal of pathology 2019 Nov;189(11):2340-2356
The American journal of pathology 2019 Nov;189(11):2340-2356
RNAase III-Type Enzyme Dicer Regulates Mitochondrial Fatty Acid Oxidative Metabolism in Cardiac Mesenchymal Stem Cells.
Su X, Jin Y, Shen Y, Kim IM, Weintraub NL, Tang Y
International journal of molecular sciences 2019 Nov 7;20(22)
International journal of molecular sciences 2019 Nov 7;20(22)
Chronic Ethanol Exposure and Withdrawal Impair Synaptic GABAA Receptor-Mediated Neurotransmission in Deep-Layer Prefrontal Cortex.
Hughes BA, Bohnsack JP, O'Buckley TK, Herman MA, Morrow AL
Alcoholism, clinical and experimental research 2019 May;43(5):822-832
Alcoholism, clinical and experimental research 2019 May;43(5):822-832
Lack of Myosin X Enhances Osteoclastogenesis and Increases Cell Surface Unc5b in Osteoclast-Lineage Cells.
Wang B, Pan JX, Yu H, Xiong L, Zhao K, Xiong S, Guo JP, Lin S, Sun D, Zhao L, Guo H, Mei L, Xiong WC
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2019 May;34(5):939-954
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2019 May;34(5):939-954
Evidence for a Novel Regulatory Interaction Involving Cyclin D1, Lipid Droplets, Lipolysis, and Cell Cycle Progression in Hepatocytes.
Wu H, Ploeger JM, Kamarajugadda S, Mashek DG, Mashek MT, Manivel JC, Shekels LL, Lapiro JL, Albrecht JH
Hepatology communications 2019 Mar;3(3):406-422
Hepatology communications 2019 Mar;3(3):406-422
Efficacy of leukemia inhibitory factor as a therapeutic for permanent large vessel stroke differs among aged male and female rats.
Davis SM, Collier LA, Goodwin S, Lukins DE, Powell DK, Pennypacker KR
Brain research 2019 Mar 15;1707:62-73
Brain research 2019 Mar 15;1707:62-73
H727 cells are inherently resistant to the proteasome inhibitor carfilzomib, yet require proteasome activity for cell survival and growth.
Lee MJ, Miller Z, Park JE, Bhattarai D, Lee W, Kim KB
Scientific reports 2019 Mar 11;9(1):4089
Scientific reports 2019 Mar 11;9(1):4089
Long Noncoding RNA ELIT-1 Acts as a Smad3 Cofactor to Facilitate TGFβ/Smad Signaling and Promote Epithelial-Mesenchymal Transition.
Sakai S, Ohhata T, Kitagawa K, Uchida C, Aoshima T, Niida H, Suzuki T, Inoue Y, Miyazawa K, Kitagawa M
Cancer research 2019 Jun 1;79(11):2821-2838
Cancer research 2019 Jun 1;79(11):2821-2838
Phenethyl isothiocyanate stimulates glucose uptake through the Akt pathway in C2C12 myotubes.
Chiba M, Ito Y, Nagasawa T
Bioscience, biotechnology, and biochemistry 2019 Jul;83(7):1319-1328
Bioscience, biotechnology, and biochemistry 2019 Jul;83(7):1319-1328
Induced Chromosomal Aneuploidy Results in Global and Consistent Deregulation of the Transcriptome of Cancer Cells.
Wangsa D, Braun R, Stuelten CH, Brown M, Bauer KM, Emons G, Weston LA, Hu Y, Yang HH, Vila-Casadesús M, Lee MP, Brauer P, Warner L, Upender M, Hummon AB, Camps J, Ried T
Neoplasia (New York, N.Y.) 2019 Jul;21(7):721-729
Neoplasia (New York, N.Y.) 2019 Jul;21(7):721-729
Magmas inhibition as a potential treatment strategy in malignant glioma.
Di K, Lomeli N, Bota DA, Das BC
Journal of neuro-oncology 2019 Jan;141(2):267-276
Journal of neuro-oncology 2019 Jan;141(2):267-276
Autophagy inhibition of cancer stem cells promotes the efficacy of cisplatin against non-small cell lung carcinoma.
Hao C, Liu G, Tian G
Therapeutic advances in respiratory disease 2019 Jan-Dec;13:1753466619866097
Therapeutic advances in respiratory disease 2019 Jan-Dec;13:1753466619866097
Novel STAT3 Inhibitor LDOC1 Targets Phospho-JAK2 for Degradation by Interacting with LNX1 and Regulates the Aggressiveness of Lung Cancer.
Lee CH, Yang JR, Chen CY, Tsai MH, Hung PF, Chen SJ, Chiang SL, Chang H, Lin P
Cancers 2019 Jan 9;11(1)
Cancers 2019 Jan 9;11(1)
Differential anti-tumour effects of MTH1 inhibitors in patient-derived 3D colorectal cancer cultures.
van der Waals LM, Laoukili J, Jongen JMJ, Raats DA, Borel Rinkes IHM, Kranenburg O
Scientific reports 2019 Jan 28;9(1):819
Scientific reports 2019 Jan 28;9(1):819
In vivo proximity proteomics of nascent synapses reveals a novel regulator of cytoskeleton-mediated synaptic maturation.
Spence EF, Dube S, Uezu A, Locke M, Soderblom EJ, Soderling SH
Nature communications 2019 Jan 23;10(1):386
Nature communications 2019 Jan 23;10(1):386
DLIC1, but not DLIC2, is upregulated in colon cancer and this contributes to proliferative overgrowth and migratory characteristics of cancer cells.
Even I, Reidenbach S, Schlechter T, Berns N, Herold R, Roth W, Krunic D, Riechmann V, Hofmann I
The FEBS journal 2019 Feb;286(4):803-820
The FEBS journal 2019 Feb;286(4):803-820
Novel Compound Heterozygote Mutation in IL10RA in a Patient With Very Early-Onset Inflammatory Bowel Disease.
Oh SH, Sung YH, Kim I, Sim CK, Lee JH, Baek M, Pack CG, Seok C, Seo EJ, Lee MS, Kim KM
Inflammatory bowel diseases 2019 Feb 21;25(3):498-509
Inflammatory bowel diseases 2019 Feb 21;25(3):498-509
Diurnal Rhythms Spatially and Temporally Organize Autophagy.
Ryzhikov M, Ehlers A, Steinberg D, Xie W, Oberlander E, Brown S, Gilmore PE, Townsend RR, Lane WS, Dolinay T, Nakahira K, Choi AMK, Haspel JA
Cell reports 2019 Feb 12;26(7):1880-1892.e6
Cell reports 2019 Feb 12;26(7):1880-1892.e6
Prostate Tumor Cell-Derived IL1β Induces an Inflammatory Phenotype in Bone Marrow Adipocytes and Reduces Sensitivity to Docetaxel via Lipolysis-Dependent Mechanisms.
Herroon MK, Diedrich JD, Rajagurubandara E, Martin C, Maddipati KR, Kim S, Heath EI, Granneman J, Podgorski I
Molecular cancer research : MCR 2019 Dec;17(12):2508-2521
Molecular cancer research : MCR 2019 Dec;17(12):2508-2521
Repurposing Itraconazole Loaded PLGA Nanoparticles for Improved Antitumor Efficacy in Non-Small Cell Lung Cancers.
Alhakamy NA, Md S
Pharmaceutics 2019 Dec 16;11(12)
Pharmaceutics 2019 Dec 16;11(12)
Nerve regeneration in rat peripheral nerve allografts: Evaluation of cold-inducible RNA-binding protein in nerve storage and regeneration.
Li Z, Zhang S, Li J, Zeng H, Wang Y, Huang Y
The Journal of comparative neurology 2019 Dec 1;527(17):2885-2895
The Journal of comparative neurology 2019 Dec 1;527(17):2885-2895
Semaphorin 4A acts in a feed-forward loop with NF-κB pathway to exacerbate catabolic effect of IL-1β on chondrocytes.
Zhang H, Wei Q, Xiang X, Zhou B, Chen J, Li J, Li Q, Xiong H, Liu F
International immunopharmacology 2019 Apr;69:88-94
International immunopharmacology 2019 Apr;69:88-94
Neuroprotective activity of leukemia inhibitory factor is relayed through myeloid zinc finger-1 in a rat model of stroke.
Davis SM, Collier LA, Foran EA, Leonardo CC, Ajmo CT Jr, Pennypacker KR
Metabolic brain disease 2019 Apr;34(2):631-640
Metabolic brain disease 2019 Apr;34(2):631-640
Systemic inactivation of hypoxia-inducible factor prolyl 4-hydroxylase 2 in mice protects from alcohol-induced fatty liver disease.
Laitakari A, Ollonen T, Kietzmann T, Walkinshaw G, Mennerich D, Izzi V, Haapasaari KM, Myllyharju J, Serpi R, Dimova EY, Koivunen P
Redox biology 2019 Apr;22:101145
Redox biology 2019 Apr;22:101145
β1 Syntrophin Supports Autophagy Initiation and Protects against Cerulein-Induced Acute Pancreatitis.
Ye R, Onodera T, Blanchard PG, Kusminski CM, Esser V, Brekken RA, Scherer PE
The American journal of pathology 2019 Apr;189(4):813-825
The American journal of pathology 2019 Apr;189(4):813-825
Modulation of the ATM/autophagy pathway by a G-quadruplex ligand tips the balance between senescence and apoptosis in cancer cells.
Beauvarlet J, Bensadoun P, Darbo E, Labrunie G, Rousseau B, Richard E, Draskovic I, Londono-Vallejo A, Dupuy JW, Nath Das R, Guédin A, Robert G, Orange F, Croce S, Valesco V, Soubeyran P, Ryan KM, Mergny JL, Djavaheri-Mergny M
Nucleic acids research 2019 Apr 8;47(6):2739-2756
Nucleic acids research 2019 Apr 8;47(6):2739-2756
Modified Sijunzi decoction can alleviate cisplatin-induced toxicity and prolong the survival time of cachectic mice by recovering muscle atrophy.
Chen JM, Yang TT, Cheng TS, Hsiao TF, Chang PM, Leu JY, Wang FS, Hsu SL, Huang CF, Lai JM
Journal of ethnopharmacology 2019 Apr 6;233:47-55
Journal of ethnopharmacology 2019 Apr 6;233:47-55
Biological effects of whole Z.Officinale extract on chronic myeloid leukemia cell line K562.
Mega Tiber P, Kocyigit Sevinc S, Kilinc O, Orun O
Gene 2019 Apr 15;692:217-222
Gene 2019 Apr 15;692:217-222
Hypercapnic and Hypoxic Respiratory Response During Wakefulness and Sleep in a Streptozotocin Model of Alzheimer's Disease in Rats.
Vicente MC, Almeida MC, Bícego KC, Carrettiero DC, Gargaglioni LH
Journal of Alzheimer's disease : JAD 2018;65(4):1159-1174
Journal of Alzheimer's disease : JAD 2018;65(4):1159-1174
The activation of G protein-coupled estrogen receptor induces relaxation via cAMP as well as potentiates contraction via EGFR transactivation in porcine coronary arteries.
Yu X, Stallone JN, Heaps CL, Han G
PloS one 2018;13(1):e0191418
PloS one 2018;13(1):e0191418
Activation of spinal dorsal horn P2Y13 receptors can promote the expression of IL-1β and IL-6 in rats with diabetic neuropathic pain.
Zhou R, Xu T, Liu X, Chen Y, Kong D, Tian H, Yue M, Huang D, Zeng J
Journal of pain research 2018;11:615-628
Journal of pain research 2018;11:615-628
Suppression of m(6)A reader Ythdf2 promotes hematopoietic stem cell expansion.
Li Z, Qian P, Shao W, Shi H, He XC, Gogol M, Yu Z, Wang Y, Qi M, Zhu Y, Perry JM, Zhang K, Tao F, Zhou K, Hu D, Han Y, Zhao C, Alexander R, Xu H, Chen S, Peak A, Hall K, Peterson M, Perera A, Haug JS, Parmely T, Li H, Shen B, Zeitlinger J, He C, Li L
Cell research 2018 Sep;28(9):904-917
Cell research 2018 Sep;28(9):904-917
Positional integration of lung adenocarcinoma susceptibility loci with primary human alveolar epithelial cell epigenomes.
Yang C, Stueve TR, Yan C, Rhie SK, Mullen DJ, Luo J, Zhou B, Borok Z, Marconett CN, Offringa IA
Epigenomics 2018 Sep;10(9):1167-1187
Epigenomics 2018 Sep;10(9):1167-1187
Caspase-11 auto-proteolysis is crucial for noncanonical inflammasome activation.
Lee BL, Stowe IB, Gupta A, Kornfeld OS, Roose-Girma M, Anderson K, Warming S, Zhang J, Lee WP, Kayagaki N
The Journal of experimental medicine 2018 Sep 3;215(9):2279-2288
The Journal of experimental medicine 2018 Sep 3;215(9):2279-2288
Cancer-associated 2-oxoglutarate analogues modify histone methylation by inhibiting histone lysine demethylases.
Laukka T, Myllykoski M, Looper RE, Koivunen P
Journal of molecular biology 2018 Sep 14;430(18 Pt B):3081-3092
Journal of molecular biology 2018 Sep 14;430(18 Pt B):3081-3092
Thermoregulatory profile of neurodegeneration-induced dementia of the Alzheimer's type using intracerebroventricular streptozotocin in rats.
Motzko-Soares ACP, Vizin RCL, Martins TMS, Hungaro ARO, Sato JR, Almeida MC, Carrettiero DC
Acta physiologica (Oxford, England) 2018 Oct;224(2):e13084
Acta physiologica (Oxford, England) 2018 Oct;224(2):e13084
Feedback control of the CXCR7/CXCL11 chemokine axis by estrogen receptor α in ovarian cancer.
Benhadjeba S, Edjekouane L, Sauvé K, Carmona E, Tremblay A
Molecular oncology 2018 Oct;12(10):1689-1705
Molecular oncology 2018 Oct;12(10):1689-1705
Quantitative Proteomic Profiling Reveals Key Pathways in the Anticancer Action of Methoxychalcone Derivatives in Triple Negative Breast Cancer.
Going CC, Tailor D, Kumar V, Birk AM, Pandrala M, Rice MA, Stoyanova T, Malhotra S, Pitteri SJ
Journal of proteome research 2018 Oct 5;17(10):3574-3585
Journal of proteome research 2018 Oct 5;17(10):3574-3585
Leukemia inhibitory factor modulates the peripheral immune response in a rat model of emergent large vessel occlusion.
Davis SM, Collier LA, Winford ED, Leonardo CC, Ajmo CT Jr, Foran EA, Kopper TJ, Gensel JC, Pennypacker KR
Journal of neuroinflammation 2018 Oct 15;15(1):288
Journal of neuroinflammation 2018 Oct 15;15(1):288
Context-enriched interactome powered by proteomics helps the identification of novel regulators of macrophage activation.
Halu A, Wang JG, Iwata H, Mojcher A, Abib AL, Singh SA, Aikawa M, Sharma A
eLife 2018 Oct 10;7
eLife 2018 Oct 10;7
Sarcoglycan Alpha Mitigates Neuromuscular Junction Decline in Aged Mice by Stabilizing LRP4.
Zhao K, Shen C, Li L, Wu H, Xing G, Dong Z, Jing H, Chen W, Zhang H, Tan Z, Pan J, Xiong L, Wang H, Cui W, Sun XD, Li S, Huang X, Xiong WC, Mei L
The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Oct 10;38(41):8860-8873
The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Oct 10;38(41):8860-8873
Endothelial Cell-Specific Inactivation of TSPAN12 (Tetraspanin 12) Reveals Pathological Consequences of Barrier Defects in an Otherwise Intact Vasculature.
Zhang C, Lai MB, Pedler MG, Johnson V, Adams RH, Petrash JM, Chen Z, Junge HJ
Arteriosclerosis, thrombosis, and vascular biology 2018 Nov;38(11):2691-2705
Arteriosclerosis, thrombosis, and vascular biology 2018 Nov;38(11):2691-2705
Novel AR-12 derivatives, P12-23 and P12-34, inhibit flavivirus replication by blocking host de novo pyrimidine biosynthesis.
Yang CF, Gopula B, Liang JJ, Li JK, Chen SY, Lee YL, Chen CS, Lin YL
Emerging microbes & infections 2018 Nov 21;7(1):187
Emerging microbes & infections 2018 Nov 21;7(1):187
Reduced AMPK activation and increased HCAR activation drive anti-inflammatory response and neuroprotection in glaucoma.
Harun-Or-Rashid M, Inman DM
Journal of neuroinflammation 2018 Nov 13;15(1):313
Journal of neuroinflammation 2018 Nov 13;15(1):313
Comparative immunohistochemical characterization of interstitial cells in the urinary bladder of human, guinea pig and pig.
Steiner C, Gevaert T, Ganzer R, De Ridder D, Neuhaus J
Histochemistry and cell biology 2018 May;149(5):491-501
Histochemistry and cell biology 2018 May;149(5):491-501
Dimerization of sortilin regulates its trafficking to extracellular vesicles.
Itoh S, Mizuno K, Aikawa M, Aikawa E
The Journal of biological chemistry 2018 Mar 23;293(12):4532-4544
The Journal of biological chemistry 2018 Mar 23;293(12):4532-4544
Intracellular lipid metabolism impairs β cell compensation during diet-induced obesity.
Ye R, Gordillo R, Shao M, Onodera T, Chen Z, Chen S, Lin X, SoRelle JA, Li X, Tang M, Keller MP, Kuliawat R, Attie AD, Gupta RK, Holland WL, Beutler B, Herz J, Scherer PE
The Journal of clinical investigation 2018 Mar 1;128(3):1178-1189
The Journal of clinical investigation 2018 Mar 1;128(3):1178-1189
Kaempferol protects against propacetamol-induced acute liver injury through CYP2E1 inactivation, UGT1A1 activation, and attenuation of oxidative stress, inflammation and apoptosis in mice.
Tsai MS, Wang YH, Lai YY, Tsou HK, Liou GG, Ko JL, Wang SH
Toxicology letters 2018 Jun 15;290:97-109
Toxicology letters 2018 Jun 15;290:97-109
Inhibition of Japanese encephalitis virus infection by the host zinc-finger antiviral protein.
Chiu HP, Chiu H, Yang CF, Lee YL, Chiu FL, Kuo HC, Lin RJ, Lin YL
PLoS pathogens 2018 Jul;14(7):e1007166
PLoS pathogens 2018 Jul;14(7):e1007166
Characterization and use of the novel human multiple myeloma cell line MC-B11/14 to study biological consequences of CRISPR-mediated loss of immunoglobulin A heavy chain.
Walters DK, Arendt BK, Tschumper RC, Wu X, Jelinek DF
Experimental hematology 2018 Jan;57:42-49.e1
Experimental hematology 2018 Jan;57:42-49.e1
Mutations in SELENBP1, encoding a novel human methanethiol oxidase, cause extraoral halitosis.
Pol A, Renkema GH, Tangerman A, Winkel EG, Engelke UF, de Brouwer APM, Lloyd KC, Araiza RS, van den Heuvel L, Omran H, Olbrich H, Oude Elberink M, Gilissen C, Rodenburg RJ, Sass JO, Schwab KO, Schäfer H, Venselaar H, Sequeira JS, Op den Camp HJM, Wevers RA
Nature genetics 2018 Jan;50(1):120-129
Nature genetics 2018 Jan;50(1):120-129
VEGF secreted by mesenchymal stem cells mediates the differentiation of endothelial progenitor cells into endothelial cells via paracrine mechanisms.
Ge Q, Zhang H, Hou J, Wan L, Cheng W, Wang X, Dong D, Chen C, Xia J, Guo J, Chen X, Wu X
Molecular medicine reports 2018 Jan;17(1):1667-1675
Molecular medicine reports 2018 Jan;17(1):1667-1675
Clemastine rescues myelination defects and promotes functional recovery in hypoxic brain injury.
Cree BAC, Niu J, Hoi KK, Zhao C, Caganap SD, Henry RG, Dao DQ, Zollinger DR, Mei F, Shen YA, Franklin RJM, Ullian EM, Xiao L, Chan JR, Fancy SPJ
Brain : a journal of neurology 2018 Jan 1;141(1):85-98
Brain : a journal of neurology 2018 Jan 1;141(1):85-98
Antrodia cinnamomea reduces obesity and modulates the gut microbiota in high-fat diet-fed mice.
Chang CJ, Lu CC, Lin CS, Martel J, Ko YF, Ojcius DM, Wu TR, Tsai YH, Yeh TS, Lu JJ, Lai HC, Young JD
International journal of obesity (2005) 2018 Feb;42(2):231-243
International journal of obesity (2005) 2018 Feb;42(2):231-243
Triple Vectors Expand AAV Transfer Capacity in the Retina.
Maddalena A, Tornabene P, Tiberi P, Minopoli R, Manfredi A, Mutarelli M, Rossi S, Simonelli F, Naggert JK, Cacchiarelli D, Auricchio A
Molecular therapy : the journal of the American Society of Gene Therapy 2018 Feb 7;26(2):524-541
Molecular therapy : the journal of the American Society of Gene Therapy 2018 Feb 7;26(2):524-541
ASC- and caspase-8-dependent apoptotic pathway diverges from the NLRC4 inflammasome in macrophages.
Lee BL, Mirrashidi KM, Stowe IB, Kummerfeld SK, Watanabe C, Haley B, Cuellar TL, Reichelt M, Kayagaki N
Scientific reports 2018 Feb 28;8(1):3788
Scientific reports 2018 Feb 28;8(1):3788
Quantitatively Predictable Control of Cellular Protein Levels through Proteasomal Degradation.
Zhao W, Pferdehirt L, Segatori L
ACS synthetic biology 2018 Feb 16;7(2):540-552
ACS synthetic biology 2018 Feb 16;7(2):540-552
Pyruvate dehydrogenase complex and lactate dehydrogenase are targets for therapy of acute liver failure.
Ferriero R, Nusco E, De Cegli R, Carissimo A, Manco G, Brunetti-Pierri N
Journal of hepatology 2018 Aug;69(2):325-335
Journal of hepatology 2018 Aug;69(2):325-335
High-Throughput Screening Identifies Kinase Inhibitors That Increase Dual Adeno-Associated Viral Vector Transduction In Vitro and in Mouse Retina.
Maddalena A, Dell'Aquila F, Giovannelli P, Tiberi P, Wanderlingh LG, Montefusco S, Tornabene P, Iodice C, Visconte F, Carissimo A, Medina DL, Castoria G, Auricchio A
Human gene therapy 2018 Aug;29(8):886-901
Human gene therapy 2018 Aug;29(8):886-901
Intrahepatic hepatitis B virus large surface antigen induces hepatocyte hyperploidy via failure of cytokinesis.
Li TN, Wu YJ, Tsai HW, Sun CP, Wu YH, Wu HL, Pei YN, Lu KY, Yen TT, Chang CW, Chan HL, Tao MH, Liou JY, Chang MD, Su IJ, Wang LH
The Journal of pathology 2018 Aug;245(4):502-513
The Journal of pathology 2018 Aug;245(4):502-513
Dopamine Triggers the Maturation of Striatal Spiny Projection Neuron Excitability during a Critical Period.
Lieberman OJ, McGuirt AF, Mosharov EV, Pigulevskiy I, Hobson BD, Choi S, Frier MD, Santini E, Borgkvist A, Sulzer D
Neuron 2018 Aug 8;99(3):540-554.e4
Neuron 2018 Aug 8;99(3):540-554.e4
Identification and characterization of a novel chemically induced allele at the planar cell polarity gene Vangl2.
El-Hassan AR, Leung V, Kharfallah F, Guyot MC, Allache R, Gros P, Kibar Z
Mammalian genome : official journal of the International Mammalian Genome Society 2018 Apr;29(3-4):229-244
Mammalian genome : official journal of the International Mammalian Genome Society 2018 Apr;29(3-4):229-244
Effects of Electroacupuncture on Methamphetamine-Induced Behavioral Changes in Mice.
Ho TJ, Lee CW, Lu ZY, Lane HY, Tsai MH, Ho IK, Huang CL, Chiang YC
Evidence-based complementary and alternative medicine : eCAM 2017;2017:5642708
Evidence-based complementary and alternative medicine : eCAM 2017;2017:5642708
Astrocyte heterogeneity across the brain and spinal cord occurs developmentally, in adulthood and in response to demyelination.
Yoon H, Walters G, Paulsen AR, Scarisbrick IA
PloS one 2017;12(7):e0180697
PloS one 2017;12(7):e0180697
Characterization of a panel of monoclonal antibodies recognizing specific epitopes on GFAP.
Lin NH, Messing A, Perng MD
PloS one 2017;12(7):e0180694
PloS one 2017;12(7):e0180694
Oxidative stress and expression of insulin signaling proteins in the brain of diabetic rats: Role of Nigella sativa oil and antidiabetic drugs.
Balbaa M, Abdulmalek SA, Khalil S
PloS one 2017;12(5):e0172429
PloS one 2017;12(5):e0172429
Attenuation of the Infiltration of Angiotensin II Expressing CD3+ T-Cells and the Modulation of Nerve Growth Factor in Lumbar Dorsal Root Ganglia - A Possible Mechanism Underpinning Analgesia Produced by EMA300, An Angiotensin II Type 2 (AT2) Receptor Antagonist.
Khan N, Muralidharan A, Smith MT
Frontiers in molecular neuroscience 2017;10:389
Frontiers in molecular neuroscience 2017;10:389
Novel role of surfactant protein A in bacterial sinusitis.
Noutsios GT, Willis AL, Ledford JG, Chang EH
International forum of allergy & rhinology 2017 Sep;7(9):897-903
International forum of allergy & rhinology 2017 Sep;7(9):897-903
Activation of dorsal horn cannabinoid CB2 receptor suppresses the expression of P2Y12 and P2Y13 receptors in neuropathic pain rats.
Niu J, Huang D, Zhou R, Yue M, Xu T, Yang J, He L, Tian H, Liu X, Zeng J
Journal of neuroinflammation 2017 Sep 12;14(1):185
Journal of neuroinflammation 2017 Sep 12;14(1):185
Fatty acid-binding protein 4 regulates fatty infiltration after rotator cuff tear by hypoxia-inducible factor 1 in mice.
Lee YS, Kim JY, Oh KS, Chung SW
Journal of cachexia, sarcopenia and muscle 2017 Oct;8(5):839-850
Journal of cachexia, sarcopenia and muscle 2017 Oct;8(5):839-850
Ethanol Exposure Regulates Gabra1 Expression via Histone Deacetylation at the Promoter in Cultured Cortical Neurons.
Bohnsack JP, Patel VK, Morrow AL
The Journal of pharmacology and experimental therapeutics 2017 Oct;363(1):1-11
The Journal of pharmacology and experimental therapeutics 2017 Oct;363(1):1-11
Downregulation of DNA repair proteins and increased DNA damage in hypoxic colon cancer cells is a therapeutically exploitable vulnerability.
Jongen JMJ, van der Waals LM, Trumpi K, Laoukili J, Peters NA, Schenning-van Schelven SJ, Govaert KM, Borel Rinkes IHM, Kranenburg O
Oncotarget 2017 Oct 17;8(49):86296-86311
Oncotarget 2017 Oct 17;8(49):86296-86311
Phenethyl isothiocyanate protects against H2O2-induced insulin resistance in 3T3-L1 adipocytes.
Nagami M, Ito Y, Nagasawa T
Bioscience, biotechnology, and biochemistry 2017 Nov;81(11):2195-2203
Bioscience, biotechnology, and biochemistry 2017 Nov;81(11):2195-2203
Study of poly-ɛ-caprolactone membranes for pleurodesis.
Chen KC, Hsieh MS, Li YR, Lin YC, Lai HS, Shieh MJ, Chen JS, Young TH
Journal of the Formosan Medical Association = Taiwan yi zhi 2017 Nov;116(11):880-887
Journal of the Formosan Medical Association = Taiwan yi zhi 2017 Nov;116(11):880-887
CD95 ligand induces senescence in mismatch repair-deficient human colon cancer via chronic caspase-mediated induction of DNA damage.
Raats DA, Frenkel N, van Schelven SJ, Rinkes IH, Laoukili J, Kranenburg O
Cell death & disease 2017 Mar 16;8(3):e2669
Cell death & disease 2017 Mar 16;8(3):e2669
Differential effect of hypoxia and acidity on lung cancer cell and fibroblast metabolism.
Giatromanolaki A, Liousia M, Arelaki S, Kalamida D, Pouliliou S, Mitrakas A, Tsolou A, Sivridis E, Koukourakis M
Biochemistry and cell biology = Biochimie et biologie cellulaire 2017 Jun;95(3):428-436
Biochemistry and cell biology = Biochimie et biologie cellulaire 2017 Jun;95(3):428-436
Expression of p63 protein in anaplastic large cell lymphoma: implications for genetic subtyping.
Wang X, Boddicker RL, Dasari S, Sidhu JS, Kadin ME, Macon WR, Ansell SM, Ketterling RP, Rech KL, Feldman AL
Human pathology 2017 Jun;64:19-27
Human pathology 2017 Jun;64:19-27
Early Passage Mesenchymal Stem Cells Display Decreased Radiosensitivity and Increased DNA Repair Activity.
Wu PK, Wang JY, Chen CF, Chao KY, Chang MC, Chen WM, Hung SC
Stem cells translational medicine 2017 Jun;6(6):1504-1514
Stem cells translational medicine 2017 Jun;6(6):1504-1514
The Effects of Selected Sesquiterpenes from Myrica rubra Essential Oil on the Efficacy of Doxorubicin in Sensitive and Resistant Cancer Cell Lines.
Ambrož M, Matoušková P, Skarka A, Zajdlová M, Žáková K, Skálová L
Molecules (Basel, Switzerland) 2017 Jun 20;22(6)
Molecules (Basel, Switzerland) 2017 Jun 20;22(6)
A CK2-RNF4 interplay coordinates non-canonical SUMOylation and degradation of nuclear receptor FXR.
Bilodeau S, Caron V, Gagnon J, Kuftedjian A, Tremblay A
Journal of molecular cell biology 2017 Jun 1;9(3):195-208
Journal of molecular cell biology 2017 Jun 1;9(3):195-208
Down-regulation of hepatocyte nuclear factor-4α and defective zonation in livers expressing mutant Z α1-antitrypsin.
Piccolo P, Annunziata P, Soria LR, Attanasio S, Barbato A, Castello R, Carissimo A, Quagliata L, Terracciano LM, Brunetti-Pierri N
Hepatology (Baltimore, Md.) 2017 Jul;66(1):124-135
Hepatology (Baltimore, Md.) 2017 Jul;66(1):124-135
Leukemia Inhibitory Factor Protects Neurons from Ischemic Damage via Upregulation of Superoxide Dismutase 3.
Davis SM, Collier LA, Leonardo CC, Seifert HA, Ajmo CT Jr, Pennypacker KR
Molecular neurobiology 2017 Jan;54(1):608-622
Molecular neurobiology 2017 Jan;54(1):608-622
Pituitary sex hormones enhance the pro‑metastatic potential of human lung cancer cells by downregulating the intracellular expression of heme oxygenase‑1.
Abdelbaset-Ismail A, Pedziwiatr D, Schneider G, Niklinski J, Charkiewicz R, Moniuszko M, Kucia M, Ratajczak MZ
International journal of oncology 2017 Jan;50(1):317-328
International journal of oncology 2017 Jan;50(1):317-328
Endothelial SCUBE2 Interacts With VEGFR2 and Regulates VEGF-Induced Angiogenesis.
Lin YC, Chao TY, Yeh CT, Roffler SR, Kannagi R, Yang RB
Arteriosclerosis, thrombosis, and vascular biology 2017 Jan;37(1):144-155
Arteriosclerosis, thrombosis, and vascular biology 2017 Jan;37(1):144-155
Efficient programming of human mesenchymal stem cell-derived hepatocytes by epigenetic regulations.
Tsai WL, Yeh PH, Tsai CY, Ting CT, Chiu YH, Tao MH, Li WC, Hung SC
Journal of gastroenterology and hepatology 2017 Jan;32(1):261-269
Journal of gastroenterology and hepatology 2017 Jan;32(1):261-269
The green microalga Tetraselmis suecica reduces oxidative stress and induces repairing mechanisms in human cells.
Sansone C, Galasso C, Orefice I, Nuzzo G, Luongo E, Cutignano A, Romano G, Brunet C, Fontana A, Esposito F, Ianora A
Scientific reports 2017 Jan 24;7:41215
Scientific reports 2017 Jan 24;7:41215
DEPTOR is a direct NOTCH1 target that promotes cell proliferation and survival in T-cell leukemia.
Hu Y, Su H, Liu C, Wang Z, Huang L, Wang Q, Liu S, Chen S, Zhou J, Li P, Chen Z, Liu H, Qing G
Oncogene 2017 Feb 23;36(8):1038-1047
Oncogene 2017 Feb 23;36(8):1038-1047
Functional Roles of Acetylated Histone Marks at Mouse Meiotic Recombination Hot Spots.
Getun IV, Wu Z, Fallahi M, Ouizem S, Liu Q, Li W, Costi R, Roush WR, Cleveland JL, Bois PRJ
Molecular and cellular biology 2017 Feb 1;37(3)
Molecular and cellular biology 2017 Feb 1;37(3)
Protease activated receptor 2 controls myelin development, resiliency and repair.
Yoon H, Radulovic M, Walters G, Paulsen AR, Drucker K, Starski P, Wu J, Fairlie DP, Scarisbrick IA
Glia 2017 Dec;65(12):2070-2086
Glia 2017 Dec;65(12):2070-2086
Stabilization of hypoxia inducible factor by cobalt chloride can alter renal epithelial transport.
Nag S, Resnick A
Physiological reports 2017 Dec;5(24)
Physiological reports 2017 Dec;5(24)
Hypoxia-inducible factor prolyl-4-hydroxylase-1 is a convergent point in the reciprocal negative regulation of NF-κB and p53 signaling pathways.
Ullah K, Rosendahl AH, Izzi V, Bergmann U, Pihlajaniemi T, Mäki JM, Myllyharju J
Scientific reports 2017 Dec 8;7(1):17220
Scientific reports 2017 Dec 8;7(1):17220
The Wnt Inhibitor Apcdd1 Coordinates Vascular Remodeling and Barrier Maturation of Retinal Blood Vessels.
Mazzoni J, Smith JR, Shahriar S, Cutforth T, Ceja B, Agalliu D
Neuron 2017 Dec 6;96(5):1055-1069.e6
Neuron 2017 Dec 6;96(5):1055-1069.e6
Involvement of mTOR-autophagy in the selection of primitive mesenchymal stem cells in chitosan film 3-dimensional culture.
Chiu HY, Tsay YG, Hung SC
Scientific reports 2017 Aug 31;7(1):10113
Scientific reports 2017 Aug 31;7(1):10113
SLC10A4 regulates IgE-mediated mast cell degranulation in vitro and mast cell-mediated reactions in vivo.
Pettersson H, Zarnegar B, Westin A, Persson V, Peuckert C, Jonsson J, Hallgren J, Kullander K
Scientific reports 2017 Apr 24;7(1):1085
Scientific reports 2017 Apr 24;7(1):1085
Retinoic acid receptor alpha drives cell cycle progression and is associated with increased sensitivity to retinoids in T-cell lymphoma.
Wang X, Dasari S, Nowakowski GS, Lazaridis KN, Wieben ED, Kadin ME, Feldman AL, Boddicker RL
Oncotarget 2017 Apr 18;8(16):26245-26255
Oncotarget 2017 Apr 18;8(16):26245-26255
Recurrence of Hyperoxaluria and Kidney Disease after Combined Intestine-Kidney Transplantation for Enteric Hyperoxaluria.
Ekser B, Mangus RS, Kubal CA, Fridell JA, Powelson JA, Nagaraju S, Mihaylov P, Phillips CL, Saxena R, Goggins WC
American journal of nephrology 2016;44(2):85-91
American journal of nephrology 2016;44(2):85-91
Association of Heme Oxygenase 1 with Lung Protection in Malaria-Associated ALI/ARDS.
Pereira ML, Ortolan LS, Sercundes MK, Debone D, Murillo O, Lima FA, Marinho CR, Epiphanio S
Mediators of inflammation 2016;2016:4158698
Mediators of inflammation 2016;2016:4158698
The Microtubule-Associated Protein Tau and Its Relevance for Pancreatic Beta Cells.
Maj M, Hoermann G, Rasul S, Base W, Wagner L, Attems J
Journal of diabetes research 2016;2016:1964634
Journal of diabetes research 2016;2016:1964634
MicroRNA-21 Increases Proliferation and Cisplatin Sensitivity of Osteosarcoma-Derived Cells.
Vanas V, Haigl B, Stockhammer V, Sutterlüty-Fall H
PloS one 2016;11(8):e0161023
PloS one 2016;11(8):e0161023
Targeting the thrombin receptor modulates inflammation and astrogliosis to improve recovery after spinal cord injury.
Radulovic M, Yoon H, Wu J, Mustafa K, Scarisbrick IA
Neurobiology of disease 2016 Sep;93:226-42
Neurobiology of disease 2016 Sep;93:226-42
Aberrant Subcellular Dynamics of Sigma-1 Receptor Mutants Underlying Neuromuscular Diseases.
Wong AY, Hristova E, Ahlskog N, Tasse LA, Ngsee JK, Chudalayandi P, Bergeron R
Molecular pharmacology 2016 Sep;90(3):238-53
Molecular pharmacology 2016 Sep;90(3):238-53
Effects of a Sublethal and Transient Stress of the Endoplasmic Reticulum on the Mitochondrial Population.
Vannuvel K, Van Steenbrugge M, Demazy C, Ninane N, Fattaccioli A, Fransolet M, Renard P, Raes M, Arnould T
Journal of cellular physiology 2016 Sep;231(9):1913-31
Journal of cellular physiology 2016 Sep;231(9):1913-31
Lack of P4H-TM in mice results in age-related retinal and renal alterations.
Leinonen H, Rossi M, Salo AM, Tiainen P, Hyvärinen J, Pitkänen M, Sormunen R, Miinalainen I, Zhang C, Soininen R, Kivirikko KI, Koskelainen A, Tanila H, Myllyharju J, Koivunen P
Human molecular genetics 2016 Sep 1;25(17):3810-3823
Human molecular genetics 2016 Sep 1;25(17):3810-3823
Farnesoid X receptor activation increases reverse cholesterol transport by modulating bile acid composition and cholesterol absorption in mice.
Xu Y, Li F, Zalzala M, Xu J, Gonzalez FJ, Adorini L, Lee YK, Yin L, Zhang Y
Hepatology (Baltimore, Md.) 2016 Oct;64(4):1072-85
Hepatology (Baltimore, Md.) 2016 Oct;64(4):1072-85
PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation.
Iwata H, Goettsch C, Sharma A, Ricchiuto P, Goh WW, Halu A, Yamada I, Yoshida H, Hara T, Wei M, Inoue N, Fukuda D, Mojcher A, Mattson PC, Barabási AL, Boothby M, Aikawa E, Singh SA, Aikawa M
Nature communications 2016 Oct 31;7:12849
Nature communications 2016 Oct 31;7:12849
The flavonoid apigenin reduces prostate cancer CD44(+) stem cell survival and migration through PI3K/Akt/NF-κB signaling.
Erdogan S, Doganlar O, Doganlar ZB, Serttas R, Turkekul K, Dibirdik I, Bilir A
Life sciences 2016 Oct 1;162:77-86
Life sciences 2016 Oct 1;162:77-86
Regulatory effects of the L-lysine metabolites, L-2-aminoadipic acid and L-pipecolic acid, on protein turnover in C2C12 myotubes.
Sato T, Ito Y, Nagasawa T
Bioscience, biotechnology, and biochemistry 2016 Nov;80(11):2168-2175
Bioscience, biotechnology, and biochemistry 2016 Nov;80(11):2168-2175
DDR1 promotes E-cadherin stability via inhibition of integrin-β1-Src activation-mediated E-cadherin endocytosis.
Chen HR, Yeh YC, Liu CY, Wu YT, Lo FY, Tang MJ, Wang YK
Scientific reports 2016 Nov 8;6:36336
Scientific reports 2016 Nov 8;6:36336
Mitochondrial Lon is over-expressed in high-grade gliomas, and mediates hypoxic adaptation: potential role of Lon as a therapeutic target in glioma.
Di K, Lomeli N, Wood SD, Vanderwal CD, Bota DA
Oncotarget 2016 Nov 22;7(47):77457-77467
Oncotarget 2016 Nov 22;7(47):77457-77467
Scriptaid overcomes hypoxia-induced cisplatin resistance in both wild-type and mutant p53 lung cancer cells.
Pradhan S, Mahajan D, Kaur P, Pandey N, Sharma C, Srivastava T
Oncotarget 2016 Nov 1;7(44):71841-71855
Oncotarget 2016 Nov 1;7(44):71841-71855
Inter-domain tagging implicates caveolin-1 in insulin receptor trafficking and Erk signaling bias in pancreatic beta-cells.
Boothe T, Lim GE, Cen H, Skovsø S, Piske M, Li SN, Nabi IR, Gilon P, Johnson JD
Molecular metabolism 2016 May;5(5):366-378
Molecular metabolism 2016 May;5(5):366-378
The small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alpha.
Hong MN, Nam KY, Kim KK, Kim SY, Kim I
Cell stress & chaperones 2016 May;21(3):485-97
Cell stress & chaperones 2016 May;21(3):485-97
HIF-P4H-2 deficiency protects against skeletal muscle ischemia-reperfusion injury.
Karsikas S, Myllymäki M, Heikkilä M, Sormunen R, Kivirikko KI, Myllyharju J, Serpi R, Koivunen P
Journal of molecular medicine (Berlin, Germany) 2016 Mar;94(3):301-10
Journal of molecular medicine (Berlin, Germany) 2016 Mar;94(3):301-10
Diluted serum from calorie-restricted animals promotes mitochondrial β-cell adaptations and protect against glucolipotoxicity.
Cerqueira FM, Chausse B, Baranovski BM, Liesa M, Lewis EC, Shirihai OS, Kowaltowski AJ
The FEBS journal 2016 Mar;283(5):822-33
The FEBS journal 2016 Mar;283(5):822-33
Chlamydia trachomatis utilizes the mammalian CLA1 lipid transporter to acquire host phosphatidylcholine essential for growth.
Cox JV, Abdelrahman YM, Peters J, Naher N, Belland RJ
Cellular microbiology 2016 Mar;18(3):305-18
Cellular microbiology 2016 Mar;18(3):305-18
Ceramide Synthase 5 Is Essential to Maintain C16:0-Ceramide Pools and Contributes to the Development of Diet-induced Obesity.
Gosejacob D, Jäger PS, Vom Dorp K, Frejno M, Carstensen AC, Köhnke M, Degen J, Dörmann P, Hoch M
The Journal of biological chemistry 2016 Mar 25;291(13):6989-7003
The Journal of biological chemistry 2016 Mar 25;291(13):6989-7003
αv Integrins combine with LC3 and atg5 to regulate Toll-like receptor signalling in B cells.
Acharya M, Sokolovska A, Tam JM, Conway KL, Stefani C, Raso F, Mukhopadhyay S, Feliu M, Paul E, Savill J, Hynes RO, Xavier RJ, Vyas JM, Stuart LM, Lacy-Hulbert A
Nature communications 2016 Mar 11;7:10917
Nature communications 2016 Mar 11;7:10917
Oncogenic roles of carbonic anhydrase 8 in human osteosarcoma cells.
Wang TK, Lin YM, Lo CM, Tang CH, Teng CL, Chao WT, Wu MH, Liu CS, Hsieh M
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jun;37(6):7989-8005
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jun;37(6):7989-8005
Differential regulation of synaptic and extrasynaptic α4 GABA(A) receptor populations by protein kinase A and protein kinase C in cultured cortical neurons.
Bohnsack JP, Carlson SL, Morrow AL
Neuropharmacology 2016 Jun;105:124-132
Neuropharmacology 2016 Jun;105:124-132
mda-7/IL-24 Induces Cell Death in Neuroblastoma through a Novel Mechanism Involving AIF and ATM.
Bhoopathi P, Lee N, Pradhan AK, Shen XN, Das SK, Sarkar D, Emdad L, Fisher PB
Cancer research 2016 Jun 15;76(12):3572-82
Cancer research 2016 Jun 15;76(12):3572-82
Genome-wide analysis of HIF-2α chromatin binding sites under normoxia in human bronchial epithelial cells (BEAS-2B) suggests its diverse functions.
Lee MC, Huang HJ, Chang TH, Huang HC, Hsieh SY, Chen YS, Chou WY, Chiang CH, Lai CH, Shiau CY
Scientific reports 2016 Jul 4;6:29311
Scientific reports 2016 Jul 4;6:29311
Lauric acid can improve the sensitization of Cetuximab in KRAS/BRAF mutated colorectal cancer cells by retrievable microRNA-378 expression.
Weng WH, Leung WH, Pang YJ, Hsu HH
Oncology reports 2016 Jan;35(1):107-16
Oncology reports 2016 Jan;35(1):107-16
Amyloid-β suppresses AMP-activated protein kinase (AMPK) signaling and contributes to α-synuclein-induced cytotoxicity.
Lin CL, Cheng YS, Li HH, Chiu PY, Chang YT, Ho YJ, Lai TJ
Experimental neurology 2016 Jan;275 Pt 1:84-98
Experimental neurology 2016 Jan;275 Pt 1:84-98
Aliskiren Reduces Hepatic steatosis and Epididymal Fat Mass and Increases Skeletal Muscle Insulin Sensitivity in High-Fat Diet-Fed Mice.
Lee KC, Hsieh YC, Yang YY, Chan CC, Huang YH, Lin HC
Scientific reports 2016 Jan 6;6:18899
Scientific reports 2016 Jan 6;6:18899
An ID2-dependent mechanism for VHL inactivation in cancer.
Lee SB, Frattini V, Bansal M, Castano AM, Sherman D, Hutchinson K, Bruce JN, Califano A, Liu G, Cardozo T, Iavarone A, Lasorella A
Nature 2016 Jan 14;529(7585):172-7
Nature 2016 Jan 14;529(7585):172-7
The carbonic anhydrase inhibitor methazolamide prevents amyloid beta-induced mitochondrial dysfunction and caspase activation protecting neuronal and glial cells in vitro and in the mouse brain.
Fossati S, Giannoni P, Solesio ME, Cocklin SL, Cabrera E, Ghiso J, Rostagno A
Neurobiology of disease 2016 Feb;86:29-40
Neurobiology of disease 2016 Feb;86:29-40
A Comprehensive Map of CNS Transduction by Eight Recombinant Adeno-associated Virus Serotypes Upon Cerebrospinal Fluid Administration in Pigs.
Sorrentino NC, Maffia V, Strollo S, Cacace V, Romagnoli N, Manfredi A, Ventrella D, Dondi F, Barone F, Giunti M, Graham AR, Huang Y, Kalled SL, Auricchio A, Bacci ML, Surace EM, Fraldi A
Molecular therapy : the journal of the American Society of Gene Therapy 2016 Feb;24(2):276-286
Molecular therapy : the journal of the American Society of Gene Therapy 2016 Feb;24(2):276-286
Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes.
Laukka T, Mariani CJ, Ihantola T, Cao JZ, Hokkanen J, Kaelin WG Jr, Godley LA, Koivunen P
The Journal of biological chemistry 2016 Feb 19;291(8):4256-65
The Journal of biological chemistry 2016 Feb 19;291(8):4256-65
The human organic cation transporter OCT1 mediates high affinity uptake of the anticancer drug daunorubicin.
Andreev E, Brosseau N, Carmona E, Mes-Masson AM, Ramotar D
Scientific reports 2016 Feb 10;6:20508
Scientific reports 2016 Feb 10;6:20508
Choroidal Involution Is Associated with a Progressive Degeneration of the Outer Retinal Function in a Model of Retinopathy of Prematurity: Early Role for IL-1β.
Zhou TE, Rivera JC, Bhosle VK, Lahaie I, Shao Z, Tahiri H, Zhu T, Polosa A, Dorfman A, Beaudry-Richard A, Costantino S, Lodygensky GA, Lachapelle P, Chemtob S
The American journal of pathology 2016 Dec;186(12):3100-3116
The American journal of pathology 2016 Dec;186(12):3100-3116
Kallikrein-related peptidase 6 exacerbates disease in an autoimmune model of multiple sclerosis.
Yoon H, Scarisbrick IA
Biological chemistry 2016 Dec 1;397(12):1277-1286
Biological chemistry 2016 Dec 1;397(12):1277-1286
A single injection of gain-of-function mutant PCSK9 adeno-associated virus vector induces cardiovascular calcification in mice with no genetic modification.
Goettsch C, Hutcheson JD, Hagita S, Rogers MA, Creager MD, Pham T, Choi J, Mlynarchik AK, Pieper B, Kjolby M, Aikawa M, Aikawa E
Atherosclerosis 2016 Aug;251:109-118
Atherosclerosis 2016 Aug;251:109-118
Differential Effects of Variations at Codon 106 on Sprouty2 Functions in Lung Cancer-Derived Cells.
Kral R, Doriguzzi A, Mayer CE, Krenbek D, Setinek U, Sutterlüty-Fall H
Journal of cellular biochemistry 2016 Aug;117(8):1822-32
Journal of cellular biochemistry 2016 Aug;117(8):1822-32
TFEB and TFE3 cooperate in the regulation of the innate immune response in activated macrophages.
Pastore N, Brady OA, Diab HI, Martina JA, Sun L, Huynh T, Lim JA, Zare H, Raben N, Ballabio A, Puertollano R
Autophagy 2016 Aug 2;12(8):1240-58
Autophagy 2016 Aug 2;12(8):1240-58
Novel small molecules potentiate premature termination codon readthrough by aminoglycosides.
Baradaran-Heravi A, Balgi AD, Zimmerman C, Choi K, Shidmoossavee FS, Tan JS, Bergeaud C, Krause A, Flibotte S, Shimizu Y, Anderson HJ, Mouly V, Jan E, Pfeifer T, Jaquith JB, Roberge M
Nucleic acids research 2016 Aug 19;44(14):6583-98
Nucleic acids research 2016 Aug 19;44(14):6583-98
Interplay between exercise and dietary fat modulates myelinogenesis in the central nervous system.
Yoon H, Kleven A, Paulsen A, Kleppe L, Wu J, Ying Z, Gomez-Pinilla F, Scarisbrick IA
Biochimica et biophysica acta 2016 Apr;1862(4):545-555
Biochimica et biophysica acta 2016 Apr;1862(4):545-555
Differential Activation of Innate Immune Pathways by Distinct Islet Amyloid Polypeptide (IAPP) Aggregates.
Westwell-Roper C, Denroche HC, Ehses JA, Verchere CB
The Journal of biological chemistry 2016 Apr 22;291(17):8908-17
The Journal of biological chemistry 2016 Apr 22;291(17):8908-17
Sexually Dimorphic Expression of eGFP Transgene in the Akr1A1 Locus of Mouse Liver Regulated by Sex Hormone-Related Epigenetic Remodeling.
Lai CW, Chen HL, Tsai TC, Chu TW, Yang SH, Chong KY, Chen CM
Scientific reports 2016 Apr 18;6:24023
Scientific reports 2016 Apr 18;6:24023
Usp9X Is Required for Lymphocyte Activation and Homeostasis through Its Control of ZAP70 Ubiquitination and PKCβ Kinase Activity.
Naik E, Dixit VM
Journal of immunology (Baltimore, Md. : 1950) 2016 Apr 15;196(8):3438-51
Journal of immunology (Baltimore, Md. : 1950) 2016 Apr 15;196(8):3438-51
Carboxylesterase 1 Is Regulated by Hepatocyte Nuclear Factor 4α and Protects Against Alcohol- and MCD diet-induced Liver Injury.
Xu J, Xu Y, Li Y, Jadhav K, You M, Yin L, Zhang Y
Scientific reports 2016 Apr 14;6:24277
Scientific reports 2016 Apr 14;6:24277
Programmed cell death 2 functions as a tumor suppressor in osteosarcoma.
Yang Y, Jin Y, Du W
International journal of clinical and experimental pathology 2015;8(9):10894-900
International journal of clinical and experimental pathology 2015;8(9):10894-900
Functional consequences of copy number variants in miscarriage.
Wen J, Hanna CW, Martell S, Leung PC, Lewis SM, Robinson WP, Stephenson MD, Rajcan-Separovic E
Molecular cytogenetics 2015;8:6
Molecular cytogenetics 2015;8:6
Wnt pathway activation and ABCB1 expression account for attenuation of proteasome inhibitor-mediated apoptosis in multidrug-resistant cancer cells.
Chong KY, Hsu CJ, Hung TH, Hu HS, Huang TT, Wang TH, Wang C, Chen CM, Choo KB, Tseng CP
Cancer biology & therapy 2015;16(1):149-59
Cancer biology & therapy 2015;16(1):149-59
The Inhibition of Heat Shock Protein 90 Facilitates the Degradation of Poly-Alanine Expanded Poly (A) Binding Protein Nuclear 1 via the Carboxyl Terminus of Heat Shock Protein 70-Interacting Protein.
Shi C, Huang X, Zhang B, Zhu D, Luo H, Lu Q, Xiong WC, Mei L, Luo S
PloS one 2015;10(9):e0138936
PloS one 2015;10(9):e0138936
Autophagosome Proteins LC3A, LC3B and LC3C Have Distinct Subcellular Distribution Kinetics and Expression in Cancer Cell Lines.
Koukourakis MI, Kalamida D, Giatromanolaki A, Zois CE, Sivridis E, Pouliliou S, Mitrakas A, Gatter KC, Harris AL
PloS one 2015;10(9):e0137675
PloS one 2015;10(9):e0137675
Angiopoietin Like Protein 2 (ANGPTL2) Promotes Adipose Tissue Macrophage and T lymphocyte Accumulation and Leads to Insulin Resistance.
Sasaki Y, Ohta M, Desai D, Figueiredo JL, Whelan MC, Sugano T, Yamabi M, Yano W, Faits T, Yabusaki K, Zhang H, Mlynarchik AK, Inoue K, Mizuno K, Aikawa M
PloS one 2015;10(7):e0131176
PloS one 2015;10(7):e0131176
Activation of AMP-Activated Protein Kinase by Adenine Alleviates TNF-Alpha-Induced Inflammation in Human Umbilical Vein Endothelial Cells.
Cheng YF, Young GH, Lin JT, Jang HH, Chen CC, Nong JY, Chen PK, Kuo CY, Kao SH, Liang YJ, Chen HM
PloS one 2015;10(11):e0142283
PloS one 2015;10(11):e0142283
TRPA1 mediates the effects of hypothermia on the monocyte inflammatory response.
Billeter AT, Galbraith N, Walker S, Lawson C, Gardner SA, Sarojini H, Galandiuk S, Polk HC Jr
Surgery 2015 Sep;158(3):646-54
Surgery 2015 Sep;158(3):646-54
Overexpression of hypoxia-inducible factor prolyl hydoxylase-2 attenuates hypoxia-induced vascular endothelial growth factor expression in luteal cells.
Zhang Z, Pang X, Tang Z, Yin D, Wang Z
Molecular medicine reports 2015 Sep;12(3):3809-3814
Molecular medicine reports 2015 Sep;12(3):3809-3814
Dietary L-Lysine Suppresses Autophagic Proteolysis and Stimulates Akt/mTOR Signaling in the Skeletal Muscle of Rats Fed a Low-Protein Diet.
Sato T, Ito Y, Nagasawa T
Journal of agricultural and food chemistry 2015 Sep 23;63(37):8192-8
Journal of agricultural and food chemistry 2015 Sep 23;63(37):8192-8
Hydrogen-rich water attenuates amyloid β-induced cytotoxicity through upregulation of Sirt1-FoxO3a by stimulation of AMP-activated protein kinase in SK-N-MC cells.
Lin CL, Huang WN, Li HH, Huang CN, Hsieh S, Lai C, Lu FJ
Chemico-biological interactions 2015 Oct 5;240:12-21
Chemico-biological interactions 2015 Oct 5;240:12-21
Amiodarone as an autophagy promoter reduces liver injury and enhances liver regeneration and survival in mice after partial hepatectomy.
Lin CW, Chen YS, Lin CC, Chen YJ, Lo GH, Lee PH, Kuo PL, Dai CY, Huang JF, Chung WL, Yu ML
Scientific reports 2015 Oct 30;5:15807
Scientific reports 2015 Oct 30;5:15807
Genetic targeting of protease activated receptor 2 reduces inflammatory astrogliosis and improves recovery of function after spinal cord injury.
Radulovic M, Yoon H, Wu J, Mustafa K, Fehlings MG, Scarisbrick IA
Neurobiology of disease 2015 Nov;83:75-89
Neurobiology of disease 2015 Nov;83:75-89
Expression and contribution of the HIF-1α/VEGF signaling pathway to luteal development and function in pregnant rats.
Wu L, Zhang Z, Pan X, Wang Z
Molecular medicine reports 2015 Nov;12(5):7153-9
Molecular medicine reports 2015 Nov;12(5):7153-9
The thrombin receptor is a critical extracellular switch controlling myelination.
Yoon H, Radulovic M, Drucker KL, Wu J, Scarisbrick IA
Glia 2015 May;63(5):846-59
Glia 2015 May;63(5):846-59
Disruption of CLPB is associated with congenital microcephaly, severe encephalopathy and 3-methylglutaconic aciduria.
Capo-Chichi JM, Boissel S, Brustein E, Pickles S, Fallet-Bianco C, Nassif C, Patry L, Dobrzeniecka S, Liao M, Labuda D, Samuels ME, Hamdan FF, Vande Velde C, Rouleau GA, Drapeau P, Michaud JL
Journal of medical genetics 2015 May;52(5):303-11
Journal of medical genetics 2015 May;52(5):303-11
Humic Acid Increases Amyloid β-Induced Cytotoxicity by Induction of ER Stress in Human SK-N-MC Neuronal Cells.
Li HH, Lu FJ, Hung HC, Liu GY, Lai TJ, Lin CL
International journal of molecular sciences 2015 May 7;16(5):10426-42
International journal of molecular sciences 2015 May 7;16(5):10426-42
Myosin phosphatase isoforms and related transcripts in the pig coronary circulation and effects of exercise and chronic occlusion.
Zheng X, Heaps CL, Fisher SA
Microvascular research 2015 Mar;98:166-71
Microvascular research 2015 Mar;98:166-71
Japanese encephalitis virus nonstructural protein NS5 interacts with mitochondrial trifunctional protein and impairs fatty acid β-oxidation.
Kao YT, Chang BL, Liang JJ, Tsai HJ, Lee YL, Lin RJ, Lin YL
PLoS pathogens 2015 Mar;11(3):e1004750
PLoS pathogens 2015 Mar;11(3):e1004750
Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition.
Bonora M, Wieckowsk MR, Chinopoulos C, Kepp O, Kroemer G, Galluzzi L, Pinton P
Oncogene 2015 Mar 19;34(12):1608
Oncogene 2015 Mar 19;34(12):1608
The metastatic tumor antigen 1-transglutaminase-2 pathway is involved in self-limitation of monosodium urate crystal-induced inflammation by upregulating TGF-β1.
Yen JH, Lin LC, Chen MC, Sarang Z, Leong PY, Chang IC, Hsu JD, Chen JH, Hsieh YF, Pallai A, Köröskényi K, Szondy Z, Tsay GJ
Arthritis research & therapy 2015 Mar 19;17:65
Arthritis research & therapy 2015 Mar 19;17:65
Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota.
Chang CJ, Lin CS, Lu CC, Martel J, Ko YF, Ojcius DM, Tseng SF, Wu TR, Chen YY, Young JD, Lai HC
Nature communications 2015 Jun 23;6:7489
Nature communications 2015 Jun 23;6:7489
A metabolic stress-inducible miR-34a-HNF4α pathway regulates lipid and lipoprotein metabolism.
Xu Y, Zalzala M, Xu J, Li Y, Yin L, Zhang Y
Nature communications 2015 Jun 23;6:7466
Nature communications 2015 Jun 23;6:7466
The increased Sprouty4 expression in response to serum is transcriptionally controlled by Specific protein 1.
Doriguzzi A, Haigl B, Gsur A, Sutterlüty-Fall H
The international journal of biochemistry & cell biology 2015 Jul;64:220-8
The international journal of biochemistry & cell biology 2015 Jul;64:220-8
Contrast Ultrasound Imaging Does Not Affect Heat Shock Protein 70 Expression in Cholesterol-Fed Rabbit Aorta.
Smith BW, Simpson DG, Miller RJ, Erdman JW Jr, O'Brien WD Jr
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine 2015 Jul;34(7):1209-16
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine 2015 Jul;34(7):1209-16
Cardiomyocytes are Protected from Antiretroviral Nucleoside Analog-Induced Mitochondrial Toxicity by Overexpression of PGC-1α.
Liu Y, Shim E, Crespo-Mejias Y, Nguyen P, Gibbons A, Liu D, Shide E, Poirier MC
Cardiovascular toxicology 2015 Jul;15(3):224-31
Cardiovascular toxicology 2015 Jul;15(3):224-31
14-3-3ζ coordinates adipogenesis of visceral fat.
Lim GE, Albrecht T, Piske M, Sarai K, Lee JTC, Ramshaw HS, Sinha S, Guthridge MA, Acker-Palmer A, Lopez AF, Clee SM, Nislow C, Johnson JD
Nature communications 2015 Jul 29;6:7671
Nature communications 2015 Jul 29;6:7671
Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) Pathway Is Induced by Mechanical Load and Reduces the Activity of Hedgehog Signaling in Chondrogenic Micromass Cell Cultures.
Juhász T, Szentléleky E, Somogyi CS, Takács R, Dobrosi N, Engler M, Tamás A, Reglődi D, Zákány R
International journal of molecular sciences 2015 Jul 29;16(8):17344-67
International journal of molecular sciences 2015 Jul 29;16(8):17344-67
IQGAP1 promotes CXCR4 chemokine receptor function and trafficking via EEA-1+ endosomes.
Bamidele AO, Kremer KN, Hirsova P, Clift IC, Gores GJ, Billadeau DD, Hedin KE
The Journal of cell biology 2015 Jul 20;210(2):257-72
The Journal of cell biology 2015 Jul 20;210(2):257-72
Soluble epoxide hydrolase activity regulates inflammatory responses and seizure generation in two mouse models of temporal lobe epilepsy.
Hung YW, Hung SW, Wu YC, Wong LK, Lai MT, Shih YH, Lee TS, Lin YY
Brain, behavior, and immunity 2015 Jan;43:118-29
Brain, behavior, and immunity 2015 Jan;43:118-29
Antrodan, a β-glucan obtained from Antrodia cinnamomea mycelia, is beneficial to benign prostate hyperplasia.
Peng CC, Lin YT, Chen KC, Chyau CC, Peng RY
Food & function 2015 Feb;6(2):635-45
Food & function 2015 Feb;6(2):635-45
EGR1 supports the osteogenic differentiation of dental stem cells.
Press T, Viale-Bouroncle S, Felthaus O, Gosau M, Morsczeck C
International endodontic journal 2015 Feb;48(2):185-92
International endodontic journal 2015 Feb;48(2):185-92
Antimicrobial peptide GW-H1-induced apoptosis of human gastric cancer AGS cell line is enhanced by suppression of autophagy.
Pan WR, Chen YL, Hsu HC, Chen WJ
Molecular and cellular biochemistry 2015 Feb;400(1-2):77-86
Molecular and cellular biochemistry 2015 Feb;400(1-2):77-86
Up-regulation of nicotinamide phosphoribosyltransferase and increase of NAD+ levels by glucose restriction extend replicative lifespan of human fibroblast Hs68 cells.
Yang NC, Song TY, Chang YZ, Chen MY, Hu ML
Biogerontology 2015 Feb;16(1):31-42
Biogerontology 2015 Feb;16(1):31-42
Attenuation of autophagic-proteolysis in C2C12 cells by saccharopine.
Sato T, Ito Y, Nagasawa T
Molecular and cellular biochemistry 2015 Dec;410(1-2):93-100
Molecular and cellular biochemistry 2015 Dec;410(1-2):93-100
Plakophilin 1-deficient cells upregulate SPOCK1: implications for prostate cancer progression.
Yang C, Fischer-Kešo R, Schlechter T, Ströbel P, Marx A, Hofmann I
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Dec;36(12):9567-77
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Dec;36(12):9567-77
Carbonic anhydrase IX overexpression regulates the migration and progression in oral squamous cell carcinoma.
Yang JS, Lin CW, Chuang CY, Su SC, Lin SH, Yang SF
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Dec;36(12):9517-24
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Dec;36(12):9517-24
SYK is a target of lymphocyte-derived microparticles in the induction of apoptosis of human retinoblastoma cells.
Qiu Q, Yang C, Xiong W, Tahiri H, Payeur M, Superstein R, Carret AS, Hamel P, Ellezam B, Martin B, Vezina M, Sapieha P, Liu G, Hardy P
Apoptosis : an international journal on programmed cell death 2015 Dec;20(12):1613-22
Apoptosis : an international journal on programmed cell death 2015 Dec;20(12):1613-22
Dengue Virus Impairs Mitochondrial Fusion by Cleaving Mitofusins.
Yu CY, Liang JJ, Li JK, Lee YL, Chang BL, Su CI, Huang WJ, Lai MM, Lin YL
PLoS pathogens 2015 Dec;11(12):e1005350
PLoS pathogens 2015 Dec;11(12):e1005350
β-Cell Insulin Secretion Requires the Ubiquitin Ligase COP1.
Suriben R, Kaihara KA, Paolino M, Reichelt M, Kummerfeld SK, Modrusan Z, Dugger DL, Newton K, Sagolla M, Webster JD, Liu J, Hebrok M, Dixit VM
Cell 2015 Dec 3;163(6):1457-67
Cell 2015 Dec 3;163(6):1457-67
The AKT signaling pathway sustains the osteogenic differentiation in human dental follicle cells.
Viale-Bouroncle S, Klingelhöffer C, Ettl T, Morsczeck C
Molecular and cellular biochemistry 2015 Aug;406(1-2):199-204
Molecular and cellular biochemistry 2015 Aug;406(1-2):199-204
Photodynamic therapy using talaporfin sodium induces concentration-dependent programmed necroptosis in human glioblastoma T98G cells.
Miki Y, Akimoto J, Moritake K, Hironaka C, Fujiwara Y
Lasers in medical science 2015 Aug;30(6):1739-45
Lasers in medical science 2015 Aug;30(6):1739-45
Exploring MicroRNA Expression Profiles Related to the mTOR Signaling Pathway in Mouse Embryonic Fibroblast Cells Treated with Polyethylenimine.
Lin CW, Jan MS, Kuo JH
Molecular pharmaceutics 2015 Aug 3;12(8):2858-68
Molecular pharmaceutics 2015 Aug 3;12(8):2858-68
α-Naphthoflavone Increases Lipid Accumulation in Mature Adipocytes and Enhances Adipocyte-Stimulated Endothelial Tube Formation.
Wang ML, Lin SH, Hou YY, Chen YH
Nutrients 2015 Apr 30;7(5):3166-83
Nutrients 2015 Apr 30;7(5):3166-83
Characterization of the enhanced apoptotic response to azidothymidine by pharmacological inhibition of NF-kB.
Matteucci C, Minutolo A, Marino-Merlo F, Grelli S, Frezza C, Mastino A, Macchi B
Life sciences 2015 Apr 15;127:90-7
Life sciences 2015 Apr 15;127:90-7
Up-regulation of microRNA-190b plays a role for decreased IGF-1 that induces insulin resistance in human hepatocellular carcinoma.
Hung TM, Ho CM, Liu YC, Lee JL, Liao YR, Wu YM, Ho MC, Chen CH, Lai HS, Lee PH
PloS one 2014;9(2):e89446
PloS one 2014;9(2):e89446
High level of plasma matrix metalloproteinase-11 is associated with clinicopathological characteristics in patients with oral squamous cell carcinoma.
Hsin CH, Chen MK, Tang CH, Lin HP, Chou MY, Lin CW, Yang SF
PloS one 2014;9(11):e113129
PloS one 2014;9(11):e113129
Androgen suppresses the proliferation of androgen receptor-positive castration-resistant prostate cancer cells via inhibition of Cdk2, CyclinA, and Skp2.
Kokontis JM, Lin HP, Jiang SS, Lin CY, Fukuchi J, Hiipakka RA, Chung CJ, Chan TM, Liao S, Chang CH, Chuu CP
PloS one 2014;9(10):e109170
PloS one 2014;9(10):e109170
Photodynamic therapy with 5-aminolevulinic acid (ALA) impairs tumor initiating and chemo-resistance property in head and neck cancer-derived cancer stem cells.
Yu CH, Yu CC
PloS one 2014;9(1):e87129
PloS one 2014;9(1):e87129
Development of an experimental model to assess the bioavailability of zinc in practical piglet diets.
Brugger D, Buffler M, Windisch W
Archives of animal nutrition 2014;68(2):73-92
Archives of animal nutrition 2014;68(2):73-92
Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation.
Van Opdenbosch N, Gurung P, Vande Walle L, Fossoul A, Kanneganti TD, Lamkanfi M
Nature communications 2014;5:3209
Nature communications 2014;5:3209
Chalcone derivatives inhibit human platelet aggregation and inhibit growth in human bladder cancer cells.
Wu CM, Lin KW, Teng CH, Huang AM, Chen YC, Yen MH, Wu WB, Pu YS, Lin CN
Biological & pharmaceutical bulletin 2014;37(7):1191-8
Biological & pharmaceutical bulletin 2014;37(7):1191-8
Chalcone derivatives inhibit human platelet aggregation and inhibit growth in human bladder cancer cells.
Wu CM, Lin KW, Teng CH, Huang AM, Chen YC, Yen MH, Wu WB, Pu YS, Lin CN
Biological & pharmaceutical bulletin 2014;37(7):1191-8
Biological & pharmaceutical bulletin 2014;37(7):1191-8
Amelioration of LPS-induced inflammation response in microglia by AMPK activation.
Chen CC, Lin JT, Cheng YF, Kuo CY, Huang CF, Kao SH, Liang YJ, Cheng CY, Chen HM
BioMed research international 2014;2014:692061
BioMed research international 2014;2014:692061
4-phenylbutyric acid attenuates endoplasmic reticulum stress-mediated pancreatic β-cell apoptosis in rats with streptozotocin-induced diabetes.
Zhu M, Guo M, Fei L, Pan XQ, Liu QQ
Endocrine 2014 Sep;47(1):129-37
Endocrine 2014 Sep;47(1):129-37
Hibernation alters the diversity and composition of mucosa-associated bacteria while enhancing antimicrobial defence in the gut of 13-lined ground squirrels.
Dill-McFarland KA, Neil KL, Zeng A, Sprenger RJ, Kurtz CC, Suen G, Carey HV
Molecular ecology 2014 Sep;23(18):4658-69
Molecular ecology 2014 Sep;23(18):4658-69
MicroRNA-205 targets tight junction-related proteins during urothelial cellular differentiation.
Chung PJ, Chi LM, Chen CL, Liang CL, Lin CT, Chang YX, Chen CH, Chang YS
Molecular & cellular proteomics : MCP 2014 Sep;13(9):2321-36
Molecular & cellular proteomics : MCP 2014 Sep;13(9):2321-36
Regulation of proximal T cell receptor signaling and tolerance induction by deubiquitinase Usp9X.
Naik E, Webster JD, DeVoss J, Liu J, Suriben R, Dixit VM
The Journal of experimental medicine 2014 Sep 22;211(10):1947-55
The Journal of experimental medicine 2014 Sep 22;211(10):1947-55
Autophagy-related gene expression analysis of wild-type and atg5 gene knockout mouse embryonic fibroblast cells treated with polyethylenimine.
Lin CW, Jan MS, Kuo JH
Molecular pharmaceutics 2014 Sep 2;11(9):3002-8
Molecular pharmaceutics 2014 Sep 2;11(9):3002-8
HIF prolyl 4-hydroxylase-2 inhibition improves glucose and lipid metabolism and protects against obesity and metabolic dysfunction.
Rahtu-Korpela L, Karsikas S, Hörkkö S, Blanco Sequeiros R, Lammentausta E, Mäkelä KA, Herzig KH, Walkinshaw G, Kivirikko KI, Myllyharju J, Serpi R, Koivunen P
Diabetes 2014 Oct;63(10):3324-33
Diabetes 2014 Oct;63(10):3324-33
Anti-cancer effects of ursane triterpenoid as a single agent and in combination with cisplatin in bladder cancer.
Lin KW, Huang AM, Lin CC, Chang CC, Hsu WC, Hour TC, Pu YS, Lin CN
European journal of pharmacology 2014 Oct 5;740:742-51
European journal of pharmacology 2014 Oct 5;740:742-51
Homologous recombination repair signaling in chemical carcinogenesis: prolonged particulate hexavalent chromium exposure suppresses the Rad51 response in human lung cells.
Qin Q, Xie H, Wise SS, Browning CL, Thompson KN, Holmes AL, Wise JP Sr
Toxicological sciences : an official journal of the Society of Toxicology 2014 Nov;142(1):117-25
Toxicological sciences : an official journal of the Society of Toxicology 2014 Nov;142(1):117-25
Effects of insulin on human pancreatic cancer progression modeled in vitro.
Chan MT, Lim GE, Skovsø S, Yang YH, Albrecht T, Alejandro EU, Hoesli CA, Piret JM, Warnock GL, Johnson JD
BMC cancer 2014 Nov 6;14:814
BMC cancer 2014 Nov 6;14:814
Hepatic carboxylesterase 1 is essential for both normal and farnesoid X receptor-controlled lipid homeostasis.
Xu J, Li Y, Chen WD, Xu Y, Yin L, Ge X, Jadhav K, Adorini L, Zhang Y
Hepatology (Baltimore, Md.) 2014 May;59(5):1761-1771
Hepatology (Baltimore, Md.) 2014 May;59(5):1761-1771
Electrophysiological characterization of spinal neuron sensitization by elevated calcium channel alpha-2-delta-1 subunit protein.
Zhou C, Luo ZD
European journal of pain (London, England) 2014 May;18(5):649-58
European journal of pain (London, England) 2014 May;18(5):649-58
Tempol protects cardiomyocytes from nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity.
Liu Y, Shim E, Nguyen P, Gibbons AT, Mitchell JB, Poirier MC
Toxicological sciences : an official journal of the Society of Toxicology 2014 May;139(1):133-41
Toxicological sciences : an official journal of the Society of Toxicology 2014 May;139(1):133-41
4-Phenylbutyric acid suppresses inflammation through regulation of endoplasmic reticulum stress of endothelial cells stimulated by uremic serum.
Zeng W, Guo YH, Qi W, Chen JG, Yang LL, Luo ZF, Mu J, Feng B
Life sciences 2014 May 8;103(1):15-24
Life sciences 2014 May 8;103(1):15-24
Mechanism of action for the cytotoxic effects of the nitric oxide prodrug JS-K in murine erythroleukemia cells.
Kaczmarek MZ, Holland RJ, Lavanier SA, Troxler JA, Fesenkova VI, Hanson CA, Cmarik JL, Saavedra JE, Keefer LK, Ruscetti SK
Leukemia research 2014 Mar;38(3):377-82
Leukemia research 2014 Mar;38(3):377-82
Regulation by resveratrol of the cellular factors mediating liver damage and regeneration after acute toxic liver injury.
Chan CC, Lee KC, Huang YH, Chou CK, Lin HC, Lee FY
Journal of gastroenterology and hepatology 2014 Mar;29(3):603-13
Journal of gastroenterology and hepatology 2014 Mar;29(3):603-13
Calcium channel α2δ1 proteins mediate trigeminal neuropathic pain states associated with aberrant excitatory synaptogenesis.
Li KW, Yu YP, Zhou C, Kim DS, Lin B, Sharp K, Steward O, Luo ZD
The Journal of biological chemistry 2014 Mar 7;289(10):7025-37
The Journal of biological chemistry 2014 Mar 7;289(10):7025-37
H3K4me3 breadth is linked to cell identity and transcriptional consistency.
Benayoun BA, Pollina EA, Ucar D, Mahmoudi S, Karra K, Wong ED, Devarajan K, Daugherty AC, Kundaje AB, Mancini E, Hitz BC, Gupta R, Rando TA, Baker JC, Snyder MP, Cherry JM, Brunet A
Cell 2014 Jul 31;158(3):673-88
Cell 2014 Jul 31;158(3):673-88
Human cytomegalovirus immediate early proteins promote degradation of connexin 43 and disrupt gap junction communication: implications for a role in gliomagenesis.
Khan Z, Yaiw KC, Wilhelmi V, Lam H, Rahbar A, Stragliotto G, Söderberg-Nauclér C
Carcinogenesis 2014 Jan;35(1):145-54
Carcinogenesis 2014 Jan;35(1):145-54
In non-small cell lung cancer mitogenic signaling leaves Sprouty1 protein levels unaffected.
Kral RM, Mayer CE, Vanas V, Gsur A, Sutterlüty-Fall H
Cell biochemistry and function 2014 Jan;32(1):96-100
Cell biochemistry and function 2014 Jan;32(1):96-100
Permanent activation of HMGA2 in lipomas mimics its temporal physiological activation linked to the gain of adipose tissue.
Thies HW, Nolte I, Wenk H, Mertens F, Bullerdiek J, Markowski DN
Obesity (Silver Spring, Md.) 2014 Jan;22(1):141-50
Obesity (Silver Spring, Md.) 2014 Jan;22(1):141-50
NOTCH1 signaling regulates the BMP2/DLX-3 directed osteogenic differentiation of dental follicle cells.
Viale-Bouroncle S, Gosau M, Morsczeck C
Biochemical and biophysical research communications 2014 Jan 10;443(2):500-4
Biochemical and biophysical research communications 2014 Jan 10;443(2):500-4
Primary macrophages rely on histone deacetylase 1 and 2 expression to induce type I interferon in response to gammaherpesvirus infection.
Mounce BC, Mboko WP, Kanack AJ, Tarakanova VL
Journal of virology 2014 Feb;88(4):2268-78
Journal of virology 2014 Feb;88(4):2268-78
High prevalence of human cytomegalovirus in brain metastases of patients with primary breast and colorectal cancers.
Taher C, Frisk G, Fuentes S, Religa P, Costa H, Assinger A, Vetvik KK, Bukholm IR, Yaiw KC, Smedby KE, Bäcklund M, Söderberg-Naucler C, Rahbar A
Translational oncology 2014 Dec;7(6):732-40
Translational oncology 2014 Dec;7(6):732-40
Hibernation induces immune changes in the lung of 13-lined ground squirrels (Ictidomys tridecemlineatus).
Bohr M, Brooks AR, Kurtz CC
Developmental and comparative immunology 2014 Dec;47(2):178-84
Developmental and comparative immunology 2014 Dec;47(2):178-84
Profiling Hsp90 differential expression and the molecular effects of the Hsp90 inhibitor IPI-504 in high-grade glioma models.
Di K, Keir ST, Alexandru-Abrams D, Gong X, Nguyen H, Friedman HS, Bota DA
Journal of neuro-oncology 2014 Dec;120(3):473-81
Journal of neuro-oncology 2014 Dec;120(3):473-81
RB maintains quiescence and prevents premature senescence through upregulation of DNMT1 in mesenchymal stromal cells.
Lin SP, Chiu FY, Wang Y, Yen ML, Kao SY, Hung SC
Stem cell reports 2014 Dec 9;3(6):975-86
Stem cell reports 2014 Dec 9;3(6):975-86
Dual disruption of DNA repair and telomere maintenance for the treatment of head and neck cancer.
Lajud SA, Nagda DA, Yamashita T, Zheng J, Tanaka N, Abuzeid WM, Civantos A, Bezpalko O, O'Malley BW Jr, Li D
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Dec 15;20(24):6465-78
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Dec 15;20(24):6465-78
Plakophilins 1 and 3 bind to FXR1 and thereby influence the mRNA stability of desmosomal proteins.
Fischer-Kešo R, Breuninger S, Hofmann S, Henn M, Röhrig T, Ströbel P, Stoecklin G, Hofmann I
Molecular and cellular biology 2014 Dec 1;34(23):4244-56
Molecular and cellular biology 2014 Dec 1;34(23):4244-56
TPX2 expression is associated with cell proliferation and patient outcome in esophageal squamous cell carcinoma.
Hsu PK, Chen HY, Yeh YC, Yen CC, Wu YC, Hsu CP, Hsu WH, Chou TY
Journal of gastroenterology 2014 Aug;49(8):1231-40
Journal of gastroenterology 2014 Aug;49(8):1231-40
Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis.
Vande Walle L, Van Opdenbosch N, Jacques P, Fossoul A, Verheugen E, Vogel P, Beyaert R, Elewaut D, Kanneganti TD, van Loo G, Lamkanfi M
Nature 2014 Aug 7;512(7512):69-73
Nature 2014 Aug 7;512(7512):69-73
Surfactant-modified nanoclay exhibits an antiviral activity with high potency and broad spectrum.
Liang JJ, Wei JC, Lee YL, Hsu SH, Lin JJ, Lin YL
Journal of virology 2014 Apr;88(8):4218-28
Journal of virology 2014 Apr;88(8):4218-28
Hypoxia after liver surgery imposes an aggressive cancer stem cell phenotype on residual tumor cells.
Govaert KM, Emmink BL, Nijkamp MW, Cheung ZJ, Steller EJ, Fatrai S, de Bruijn MT, Kranenburg O, Borel Rinkes IH
Annals of surgery 2014 Apr;259(4):750-9
Annals of surgery 2014 Apr;259(4):750-9
Trigeminal nerve injury-induced thrombospondin-4 up-regulation contributes to orofacial neuropathic pain states in a rat model.
Li KW, Kim DS, Zaucke F, Luo ZD
European journal of pain (London, England) 2014 Apr;18(4):489-95
European journal of pain (London, England) 2014 Apr;18(4):489-95
Leptin deficiency in rats results in hyperinsulinemia and impaired glucose homeostasis.
D'souza AM, Asadi A, Johnson JD, Covey SD, Kieffer TJ
Endocrinology 2014 Apr;155(4):1268-79
Endocrinology 2014 Apr;155(4):1268-79
Rapid degradation of the complement regulator, CD59, by a novel inhibitor.
Cai B, Xie S, Liu F, Simone LC, Caplan S, Qin X, Naslavsky N
The Journal of biological chemistry 2014 Apr 25;289(17):12109-25
The Journal of biological chemistry 2014 Apr 25;289(17):12109-25
Eosinophils regulate peripheral B cell numbers in both mice and humans.
Wong TW, Doyle AD, Lee JJ, Jelinek DF
Journal of immunology (Baltimore, Md. : 1950) 2014 Apr 15;192(8):3548-58
Journal of immunology (Baltimore, Md. : 1950) 2014 Apr 15;192(8):3548-58
Novel mutations in Lrp6 orthologs in mouse and human neural tube defects affect a highly dosage-sensitive Wnt non-canonical planar cell polarity pathway.
Allache R, Lachance S, Guyot MC, De Marco P, Merello E, Justice MJ, Capra V, Kibar Z
Human molecular genetics 2014 Apr 1;23(7):1687-99
Human molecular genetics 2014 Apr 1;23(7):1687-99
Reappraisal of the therapeutic role of celecoxib in cholangiocarcinoma.
Yeh CN, Chiang KC, Juang HH, S Pang JH, Yu CS, Lin KJ, Yeh TS, Jan YY
PloS one 2013;8(7):e69928
PloS one 2013;8(7):e69928
Difference in protein expression profile and chemotherapy drugs response of different progression stages of LNCaP sublines and other human prostate cancer cells.
Lin HP, Lin CY, Hsiao PH, Wang HD, Jiang SS, Hsu JM, Jim WT, Chen M, Kung HJ, Chuu CP
PloS one 2013;8(12):e82625
PloS one 2013;8(12):e82625
Harnessing gene conversion in chicken B cells to create a human antibody sequence repertoire.
Schusser B, Yi H, Collarini EJ, Izquierdo SM, Harriman WD, Etches RJ, Leighton PA
PloS one 2013;8(11):e80108
PloS one 2013;8(11):e80108
Phosphatidylinositol-3-phosphate regulates sorting and processing of amyloid precursor protein through the endosomal system.
Morel E, Chamoun Z, Lasiecka ZM, Chan RB, Williamson RL, Vetanovetz C, Dall'Armi C, Simoes S, Point Du Jour KS, McCabe BD, Small SA, Di Paolo G
Nature communications 2013;4:2250
Nature communications 2013;4:2250
Hirsutella sinensis mycelium suppresses interleukin-1β and interleukin-18 secretion by inhibiting both canonical and non-canonical inflammasomes.
Huang TT, Chong KY, Ojcius DM, Wu YH, Ko YF, Wu CY, Martel J, Lu CC, Lai HC, Young JD
Scientific reports 2013;3:1374
Scientific reports 2013;3:1374
Integrin binding and MAPK signal pathways in primary cell responses to surface chemistry of calcium silicate cements.
Shie MY, Ding SJ
Biomaterials 2013 Sep;34(28):6589-606
Biomaterials 2013 Sep;34(28):6589-606
Maspin is a marker for early recurrence in primary stage III and IV colorectal cancer.
Snoeren N, Emmink BL, Koerkamp MJ, van Hooff SR, Goos JA, van Houdt WJ, de Wit M, Prins AM, Piersma SR, Pham TV, Belt EJ, Bril H, Stockmann HB, Meijer GA, van Hillegersberg R, Holstege FC, Jimenez CR, Fijneman RJ, Kranenburg OW, Rinkes IH
British journal of cancer 2013 Sep 17;109(6):1636-47
British journal of cancer 2013 Sep 17;109(6):1636-47
Palmitate induces transcriptional regulation of BACE1 and presenilin by STAT3 in neurons mediated by astrocytes.
Liu L, Martin R, Kohler G, Chan C
Experimental neurology 2013 Oct;248:482-90
Experimental neurology 2013 Oct;248:482-90
IMP1 promotes choriocarcinoma cell migration and invasion through the novel effectors RSK2 and PPME1.
Hsieh YT, Chou MM, Chen HC, Tseng JJ
Gynecologic oncology 2013 Oct;131(1):182-90
Gynecologic oncology 2013 Oct;131(1):182-90
Kallikrein 6 signals through PAR1 and PAR2 to promote neuron injury and exacerbate glutamate neurotoxicity.
Yoon H, Radulovic M, Wu J, Blaber SI, Blaber M, Fehlings MG, Scarisbrick IA
Journal of neurochemistry 2013 Oct;127(2):283-98
Journal of neurochemistry 2013 Oct;127(2):283-98
The secretome of colon cancer stem cells contains drug-metabolizing enzymes.
Emmink BL, Verheem A, Van Houdt WJ, Steller EJ, Govaert KM, Pham TV, Piersma SR, Borel Rinkes IH, Jimenez CR, Kranenburg O
Journal of proteomics 2013 Oct 8;91:84-96
Journal of proteomics 2013 Oct 8;91:84-96
The mTOR kinase inhibitors, CC214-1 and CC214-2, preferentially block the growth of EGFRvIII-activated glioblastomas.
Gini B, Zanca C, Guo D, Matsutani T, Masui K, Ikegami S, Yang H, Nathanson D, Villa GR, Shackelford D, Zhu S, Tanaka K, Babic I, Akhavan D, Lin K, Assuncao A, Gu Y, Bonetti B, Mortensen DS, Xu S, Raymon HK, Cavenee WK, Furnari FB, James CD, Kroemer G, Heath JR, Hege K, Chopra R, Cloughesy TF, Mischel PS
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Oct 15;19(20):5722-32
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Oct 15;19(20):5722-32
Inhibition of high-mobility group box 1 in lung reduced airway inflammation and remodeling in a mouse model of chronic asthma.
Lee CC, Lai YT, Chang HT, Liao JW, Shyu WC, Li CY, Wang CN
Biochemical pharmacology 2013 Oct 1;86(7):940-9
Biochemical pharmacology 2013 Oct 1;86(7):940-9
Novel TRAF1-ALK fusion identified by deep RNA sequencing of anaplastic large cell lymphoma.
Feldman AL, Vasmatzis G, Asmann YW, Davila J, Middha S, Eckloff BW, Johnson SH, Porcher JC, Ansell SM, Caride A
Genes, chromosomes & cancer 2013 Nov;52(11):1097-102
Genes, chromosomes & cancer 2013 Nov;52(11):1097-102
Thrombospondin-4 contributes to spinal cord injury-induced changes in nociception.
Zeng J, Kim D, Li KW, Sharp K, Steward O, Zaucke F, Luo ZD
European journal of pain (London, England) 2013 Nov;17(10):1458-64
European journal of pain (London, England) 2013 Nov;17(10):1458-64
Induction of hepatocyte-like cells from mouse embryonic stem cells by lentivirus-mediated constitutive expression of Foxa2/Hnf4a.
Liu T, Zhang S, Xiang D, Wang Y
Journal of cellular biochemistry 2013 Nov;114(11):2531-41
Journal of cellular biochemistry 2013 Nov;114(11):2531-41
Overexpression of caldesmon is associated with lymph node metastasis and poorer prognosis in patients with oral cavity squamous cell carcinoma.
Chang KP, Wang CL, Kao HK, Liang Y, Liu SC, Huang LL, Hseuh C, Hsieh YJ, Chien KY, Chang YS, Yu JS, Chi LM
Cancer 2013 Nov 15;119(22):4003-11
Cancer 2013 Nov 15;119(22):4003-11
Quercetin in elimination of tumor initiating stem-like and mesenchymal transformation property in head and neck cancer.
Chang WW, Hu FW, Yu CC, Wang HH, Feng HP, Lan C, Tsai LL, Chang YC
Head & neck 2013 Mar;35(3):413-9
Head & neck 2013 Mar;35(3):413-9
Clinical significance and novel mechanism of action of kallikrein 6 in glioblastoma.
Drucker KL, Paulsen AR, Giannini C, Decker PA, Blaber SI, Blaber M, Uhm JH, O'Neill BP, Jenkins RB, Scarisbrick IA
Neuro-oncology 2013 Mar;15(3):305-18
Neuro-oncology 2013 Mar;15(3):305-18
Macrophage cathepsin K promotes prostate tumor progression in bone.
Herroon MK, Rajagurubandara E, Rudy DL, Chalasani A, Hardaway AL, Podgorski I
Oncogene 2013 Mar 21;32(12):1580-93
Oncogene 2013 Mar 21;32(12):1580-93
Cuttlefish skin papilla morphology suggests a muscular hydrostatic function for rapid changeability.
Allen JJ, Bell GR, Kuzirian AM, Hanlon RT
Journal of morphology 2013 Jun;274(6):645-56
Journal of morphology 2013 Jun;274(6):645-56
Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain.
Rafalski VA, Ho PP, Brett JO, Ucar D, Dugas JC, Pollina EA, Chow LM, Ibrahim A, Baker SJ, Barres BA, Steinman L, Brunet A
Nature cell biology 2013 Jun;15(6):614-24
Nature cell biology 2013 Jun;15(6):614-24
EGFR mutation-induced alternative splicing of Max contributes to growth of glycolytic tumors in brain cancer.
Babic I, Anderson ES, Tanaka K, Guo D, Masui K, Li B, Zhu S, Gu Y, Villa GR, Akhavan D, Nathanson D, Gini B, Mareninov S, Li R, Camacho CE, Kurdistani SK, Eskin A, Nelson SF, Yong WH, Cavenee WK, Cloughesy TF, Christofk HR, Black DL, Mischel PS
Cell metabolism 2013 Jun 4;17(6):1000-8
Cell metabolism 2013 Jun 4;17(6):1000-8
Glucocorticoids alleviate intestinal ER stress by enhancing protein folding and degradation of misfolded proteins.
Das I, Png CW, Oancea I, Hasnain SZ, Lourie R, Proctor M, Eri RD, Sheng Y, Crane DI, Florin TH, McGuckin MA
The Journal of experimental medicine 2013 Jun 3;210(6):1201-16
The Journal of experimental medicine 2013 Jun 3;210(6):1201-16
Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells.
Cai H, Peng F
Oncology reports 2013 Jul;30(1):269-75
Oncology reports 2013 Jul;30(1):269-75
Phenotypic and functional consequences of haploinsufficiency of genes from exocyst and retinoic acid pathway due to a recurrent microdeletion of 2p13.2.
Wen J, Lopes F, Soares G, Farrell SA, Nelson C, Qiao Y, Martell S, Badukke C, Bessa C, Ylstra B, Lewis S, Isoherranen N, Maciel P, Rajcan-Separovic E
Orphanet journal of rare diseases 2013 Jul 10;8:100
Orphanet journal of rare diseases 2013 Jul 10;8:100
Mutations in SYNGAP1 cause intellectual disability, autism, and a specific form of epilepsy by inducing haploinsufficiency.
Berryer MH, Hamdan FF, Klitten LL, Møller RS, Carmant L, Schwartzentruber J, Patry L, Dobrzeniecka S, Rochefort D, Neugnot-Cerioli M, Lacaille JC, Niu Z, Eng CM, Yang Y, Palardy S, Belhumeur C, Rouleau GA, Tommerup N, Immken L, Beauchamp MH, Patel GS, Majewski J, Tarnopolsky MA, Scheffzek K, Hjalgrim H, Michaud JL, Di Cristo G
Human mutation 2013 Feb;34(2):385-94
Human mutation 2013 Feb;34(2):385-94
Unsaturated fatty acids and phytosterols regulate cholesterol transporter genes in Caco-2 and HepG2 cell lines.
Park Y, Carr TP
Nutrition research (New York, N.Y.) 2013 Feb;33(2):154-61
Nutrition research (New York, N.Y.) 2013 Feb;33(2):154-61
Exercise training-enhanced, endothelium-dependent dilation mediated by altered regulation of BK(Ca) channels in collateral-dependent porcine coronary arterioles.
Xie W, Parker JL, Heaps CL
Microcirculation (New York, N.Y. : 1994) 2013 Feb;20(2):170-82
Microcirculation (New York, N.Y. : 1994) 2013 Feb;20(2):170-82
Cleome arabica leaf extract has anticancer properties in human cancer cells.
Tigrine C, Bulzomi P, Leone S, Bouriche H, Kameli A, Marino M
Pharmaceutical biology 2013 Dec;51(12):1508-14
Pharmaceutical biology 2013 Dec;51(12):1508-14
Aip regulates cAMP signalling and GH secretion in GH3 cells.
Formosa R, Xuereb-Anastasi A, Vassallo J
Endocrine-related cancer 2013 Aug;20(4):495-505
Endocrine-related cancer 2013 Aug;20(4):495-505
CXCR4 chemokine receptor signaling induces apoptosis in acute myeloid leukemia cells via regulation of the Bcl-2 family members Bcl-XL, Noxa, and Bak.
Kremer KN, Peterson KL, Schneider PA, Meng XW, Dai H, Hess AD, Smith BD, Rodriguez-Ramirez C, Karp JE, Kaufmann SH, Hedin KE
The Journal of biological chemistry 2013 Aug 9;288(32):22899-914
The Journal of biological chemistry 2013 Aug 9;288(32):22899-914
Differential proteomic analysis of cancer stem cell properties in hepatocellular carcinomas by isobaric tag labeling and mass spectrometry.
Ko CH, Cheng CF, Lai CP, Tzu TH, Chiu CW, Lin MW, Wu SY, Sun CY, Tseng HW, Wang CC, Kuo ZK, Wang LM, Chen SF
Journal of proteome research 2013 Aug 2;12(8):3573-85
Journal of proteome research 2013 Aug 2;12(8):3573-85
Sprouty2 but not Sprouty4 is a potent inhibitor of cell proliferation and migration of osteosarcoma cells.
Rathmanner N, Haigl B, Vanas V, Doriguzzi A, Gsur A, Sutterlüty-Fall H
FEBS letters 2013 Aug 19;587(16):2597-605
FEBS letters 2013 Aug 19;587(16):2597-605
PROTAC-induced proteolytic targeting.
Carmony KC, Kim KB
Methods in molecular biology (Clifton, N.J.) 2012;832:627-38
Methods in molecular biology (Clifton, N.J.) 2012;832:627-38
Suppression of extensive neurofilament phosphorylation rescues α-Internexin/peripherin-overexpressing PC12 cells from neuronal cell death.
Lee WC, Kan D, Chen YY, Han SK, Lu KS, Chien CL
PloS one 2012;7(8):e43883
PloS one 2012;7(8):e43883
Novel insights into the distribution and functional aspects of the calcium binding protein secretagogin from studies on rat brain and primary neuronal cell culture.
Maj M, Milenkovic I, Bauer J, Berggård T, Veit M, Ilhan-Mutlu A, Wagner L, Tretter V
Frontiers in molecular neuroscience 2012;5:84
Frontiers in molecular neuroscience 2012;5:84
Low-level laser therapy alleviates neuropathic pain and promotes function recovery in rats with chronic constriction injury: possible involvements in hypoxia-inducible factor 1α (HIF-1α).
Hsieh YL, Chou LW, Chang PL, Yang CC, Kao MJ, Hong CZ
The Journal of comparative neurology 2012 Sep 1;520(13):2903-16
The Journal of comparative neurology 2012 Sep 1;520(13):2903-16
Hypoxia-inducible factor-1 (HIF-1) but not HIF-2 is essential for hypoxic induction of collagen prolyl 4-hydroxylases in primary newborn mouse epiphyseal growth plate chondrocytes.
Aro E, Khatri R, Gerard-O'Riley R, Mangiavini L, Myllyharju J, Schipani E
The Journal of biological chemistry 2012 Oct 26;287(44):37134-44
The Journal of biological chemistry 2012 Oct 26;287(44):37134-44
Mechanisms of prostate permeability triggered by microbubble-mediated acoustic cavitation.
Li T, Liu G, Li J, Wang X, Liu Q, Liu Z, Du W
Cell biochemistry and biophysics 2012 Nov;64(2):147-53
Cell biochemistry and biophysics 2012 Nov;64(2):147-53
Functional and histological outcome after focal traumatic brain injury is not improved in conditional EphA4 knockout mice.
Hånell A, Clausen F, Djupsjö A, Vallstedt A, Patra K, Israelsson C, Larhammar M, Björk M, Paixão S, Kullander K, Marklund N
Journal of neurotrauma 2012 Nov 20;29(17):2660-71
Journal of neurotrauma 2012 Nov 20;29(17):2660-71
Obesity and weight loss result in increased adipose tissue ABCG1 expression in db/db mice.
Edgel KA, McMillen TS, Wei H, Pamir N, Houston BA, Caldwell MT, Mai PO, Oram JF, Tang C, Leboeuf RC
Biochimica et biophysica acta 2012 Mar;1821(3):425-34
Biochimica et biophysica acta 2012 Mar;1821(3):425-34
Angiotensin II induces extracellular matrix metalloproteinase inducer expression via an AT1R dependent pathway in aortic atherosclerotic plaque in apolipoprotein E knockout mice.
Yang LX, Yang ZH, Guo RW, Ye JS, Liu H
Journal of the renin-angiotensin-aldosterone system : JRAAS 2012 Mar;13(1):67-75
Journal of the renin-angiotensin-aldosterone system : JRAAS 2012 Mar;13(1):67-75
A selective inhibitor of the immunoproteasome subunit LMP2 induces apoptosis in PC-3 cells and suppresses tumour growth in nude mice.
Wehenkel M, Ban JO, Ho YK, Carmony KC, Hong JT, Kim KB
British journal of cancer 2012 Jun 26;107(1):53-62
British journal of cancer 2012 Jun 26;107(1):53-62
Methylation by Set9 modulates FoxO3 stability and transcriptional activity.
Calnan DR, Webb AE, White JL, Stowe TR, Goswami T, Shi X, Espejo A, Bedford MT, Gozani O, Gygi SP, Brunet A
Aging 2012 Jul;4(7):462-79
Aging 2012 Jul;4(7):462-79
β-Catenin gain of function in muscles impairs neuromuscular junction formation.
Wu H, Lu Y, Barik A, Joseph A, Taketo MM, Xiong WC, Mei L
Development (Cambridge, England) 2012 Jul;139(13):2392-404
Development (Cambridge, England) 2012 Jul;139(13):2392-404
D(-)lentiginosine-induced apoptosis involves the intrinsic pathway and is p53-independent.
Minutolo A, Grelli S, Marino-Merlo F, Cordero FM, Brandi A, Macchi B, Mastino A
Cell death & disease 2012 Jul 26;3:e358
Cell death & disease 2012 Jul 26;3:e358
2,4,5-TMBA, a natural inhibitor of cyclooxygenase-2, suppresses adipogenesis and promotes lipolysis in 3T3-L1 adipocytes.
Wu MR, Hou MH, Lin YL, Kuo CF
Journal of agricultural and food chemistry 2012 Jul 25;60(29):7262-9
Journal of agricultural and food chemistry 2012 Jul 25;60(29):7262-9
Unexpected gender difference in sensitivity to the acute toxicity of dioxin in mice.
Pohjanvirta R, Miettinen H, Sankari S, Hegde N, Lindén J
Toxicology and applied pharmacology 2012 Jul 15;262(2):167-76
Toxicology and applied pharmacology 2012 Jul 15;262(2):167-76
Distinct roles of muscle and motoneuron LRP4 in neuromuscular junction formation.
Wu H, Lu Y, Shen C, Patel N, Gan L, Xiong WC, Mei L
Neuron 2012 Jul 12;75(1):94-107
Neuron 2012 Jul 12;75(1):94-107
A neuronal death model: overexpression of neuronal intermediate filament protein peripherin in PC12 cells.
Lee WC, Chen YY, Kan D, Chien CL
Journal of biomedical science 2012 Jan 17;19:8
Journal of biomedical science 2012 Jan 17;19:8
Wnt proteins regulate acetylcholine receptor clustering in muscle cells.
Zhang B, Liang C, Bates R, Yin Y, Xiong WC, Mei L
Molecular brain 2012 Feb 6;5:7
Molecular brain 2012 Feb 6;5:7
Association of tumor-associated trypsin inhibitor (TATI) expression with molecular markers, pathologic features and clinical outcomes of urothelial carcinoma of the urinary bladder.
Patschan O, Shariat SF, Chade DC, Karakiewicz PI, Ashfaq R, Lotan Y, Hotakainen K, Stenman UH, Bjartell A
World journal of urology 2012 Dec;30(6):785-94
World journal of urology 2012 Dec;30(6):785-94
Protective role of autophagy in branched polyethylenimine (25K)- and poly(L-lysine) (30-70K)-induced cell death.
Lin CW, Jan MS, Kuo JH, Hsu LJ, Lin YS
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2012 Dec 18;47(5):865-74
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2012 Dec 18;47(5):865-74
FoxO6 regulates memory consolidation and synaptic function.
Salih DA, Rashid AJ, Colas D, de la Torre-Ubieta L, Zhu RP, Morgan AA, Santo EE, Ucar D, Devarajan K, Cole CJ, Madison DV, Shamloo M, Butte AJ, Bonni A, Josselyn SA, Brunet A
Genes & development 2012 Dec 15;26(24):2780-801
Genes & development 2012 Dec 15;26(24):2780-801
Placental, renal, and ileal sulfate transporter gene expression in mouse gestation.
Dawson PA, Rakoczy J, Simmons DG
Biology of reproduction 2012 Aug;87(2):43
Biology of reproduction 2012 Aug;87(2):43
Retinoic acid promotes proliferation of chicken primordial germ cells via activation of PI3K/Akt-mediated NF-κB signalling cascade.
Yu M, Ge C, Zeng W, Mi Y, Zhang C
Cell biology international 2012 Aug 1;36(8):705-12
Cell biology international 2012 Aug 1;36(8):705-12
Effects of tirapazamine on experimental colorectal liver metastases after radiofrequency ablation.
Govaert KM, Nijkamp MW, Emmink BL, Steller EJ, Minchinton AI, Kranenburg O, Borel Rinkes IH
The British journal of surgery 2012 Apr;99(4):567-75
The British journal of surgery 2012 Apr;99(4):567-75
Proteomics of post-traumatic proliferative vitreoretinopathy in rabbit retina reveals alterations to a variety of functional proteins.
Zhou Q, Xu G, Zhang X, Cao C, Zhou Z
Current eye research 2012 Apr;37(4):318-26
Current eye research 2012 Apr;37(4):318-26
Age-dependent decline of DNA base excision repair activity in rat cortical neurons.
Swain U, Rao KS
Mechanisms of ageing and development 2012 Apr;133(4):186-94
Mechanisms of ageing and development 2012 Apr;133(4):186-94
The effect of 17{beta}-estradiol on cholesterol content in human macrophages is influenced by the lipoprotein milieu.
Corcoran MP, Lichtenstein AH, Meydani M, Dillard A, Schaefer EJ, Lamon-Fava S
Journal of molecular endocrinology 2011;47(1):109-17
Journal of molecular endocrinology 2011;47(1):109-17
ABIN1 protein cooperates with TAX1BP1 and A20 proteins to inhibit antiviral signaling.
Gao L, Coope H, Grant S, Ma A, Ley SC, Harhaj EW
The Journal of biological chemistry 2011 Oct 21;286(42):36592-602
The Journal of biological chemistry 2011 Oct 21;286(42):36592-602
Musashi expression in β-cells coordinates insulin expression, apoptosis and proliferation in response to endoplasmic reticulum stress in diabetes.
Szabat M, Kalynyak TB, Lim GE, Chu KY, Yang YH, Asadi A, Gage BK, Ao Z, Warnock GL, Piret JM, Kieffer TJ, Johnson JD
Cell death & disease 2011 Nov 24;2:e232
Cell death & disease 2011 Nov 24;2:e232
COP1 is a tumour suppressor that causes degradation of ETS transcription factors.
Vitari AC, Leong KG, Newton K, Yee C, O'Rourke K, Liu J, Phu L, Vij R, Ferrando R, Couto SS, Mohan S, Pandita A, Hongo JA, Arnott D, Wertz IE, Gao WQ, French DM, Dixit VM
Nature 2011 May 15;474(7351):403-6
Nature 2011 May 15;474(7351):403-6
Functional role of kallikrein 6 in regulating immune cell survival.
Scarisbrick IA, Epstein B, Cloud BA, Yoon H, Wu J, Renner DN, Blaber SI, Blaber M, Vandell AG, Bryson AL
PloS one 2011 Mar 28;6(3):e18376
PloS one 2011 Mar 28;6(3):e18376
UBE2M-mediated p27(Kip1) degradation in gemcitabine cytotoxicity.
Huang AM, Kao YT, Toh S, Lin PY, Chou CH, Hu HT, Lu CY, Liou JY, Chao SY, Hour TC, Pu YS
Biochemical pharmacology 2011 Jul 1;82(1):35-42
Biochemical pharmacology 2011 Jul 1;82(1):35-42
HDAC inhibitor 4-phenylbutyrate preserves immature phenotype of human embryonic midbrain stem cells: implications for the involvement of DNA methyltransferase.
Khan Z, Akhtar M, Ekström TJ
International journal of molecular medicine 2011 Dec;28(6):977-83
International journal of molecular medicine 2011 Dec;28(6):977-83
Identification of the nanogold particle-induced endoplasmic reticulum stress by omic techniques and systems biology analysis.
Tsai YY, Huang YH, Chao YL, Hu KY, Chin LT, Chou SH, Hour AL, Yao YD, Tu CS, Liang YJ, Tsai CY, Wu HY, Tan SW, Chen HM
ACS nano 2011 Dec 27;5(12):9354-69
ACS nano 2011 Dec 27;5(12):9354-69
19-Nor-2α-(3-hydroxypropyl)-1α,25-dihydroxyvitamin D3 (MART-10) is a potent cell growth regulator with enhanced chemotherapeutic potency in liver cancer cells.
Chiang KC, Yeh CN, Chen HY, Lee JM, Juang HH, Chen MF, Takano M, Kittaka A, Chen TC
Steroids 2011 Dec 11;76(13):1513-9
Steroids 2011 Dec 11;76(13):1513-9
Aldo-keto reductase 1B7 is a target gene of FXR and regulates lipid and glucose homeostasis.
Ge X, Yin L, Ma H, Li T, Chiang JY, Zhang Y
Journal of lipid research 2011 Aug;52(8):1561-8
Journal of lipid research 2011 Aug;52(8):1561-8
Synergistic killing of colorectal cancer cells by oxaliplatin and ABT-737.
Raats DA, de Bruijn MT, Steller EJ, Emmink BL, Borel-Rinkes IH, Kranenburg O
Cellular oncology (Dordrecht) 2011 Aug;34(4):307-13
Cellular oncology (Dordrecht) 2011 Aug;34(4):307-13
A role for CD95 signaling in ischemia/reperfusion-induced invasion and outgrowth of colorectal micrometastases in mouse liver.
Nijkamp MW, Hoogwater FJ, Govaert KM, Steller EJ, Verheem A, Kranenburg O, Borel Rinkes IH
Journal of surgical oncology 2011 Aug 1;104(2):198-204
Journal of surgical oncology 2011 Aug 1;104(2):198-204
Adipocyte expression of the glucose-dependent insulinotropic polypeptide receptor involves gene regulation by PPARγ and histone acetylation.
Kim SJ, Nian C, McIntosh CH
Journal of lipid research 2011 Apr;52(4):759-70
Journal of lipid research 2011 Apr;52(4):759-70
Chromatin immunoprecipitation to analyze DNA binding sites of HMGA2.
Winter N, Nimzyk R, Bösche C, Meyer A, Bullerdiek J
PloS one 2011 Apr 14;6(4):e18837
PloS one 2011 Apr 14;6(4):e18837
Kinetics and longevity of ΦC31 integrase in mouse liver and cultured cells.
Chavez CL, Keravala A, Woodard LE, Hillman RT, Stowe TR, Chu JN, Calos MP
Human gene therapy 2010 Oct;21(10):1287-97
Human gene therapy 2010 Oct;21(10):1287-97
Inhibition of the visual cycle by A2E through direct interaction with RPE65 and implications in Stargardt disease.
Moiseyev G, Nikolaeva O, Chen Y, Farjo K, Takahashi Y, Ma JX
Proceedings of the National Academy of Sciences of the United States of America 2010 Oct 12;107(41):17551-6
Proceedings of the National Academy of Sciences of the United States of America 2010 Oct 12;107(41):17551-6
Enhanced anti-inflammatory activities of Monascus pilosus fermented products by addition of ginger to the medium.
Chen CC, Chyau CC, Liao CC, Hu TJ, Kuo CF
Journal of agricultural and food chemistry 2010 Nov 24;58(22):12006-13
Journal of agricultural and food chemistry 2010 Nov 24;58(22):12006-13
A BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling.
Hildebrand JM, Luo Z, Manske MK, Price-Troska T, Ziesmer SC, Lin W, Hostager BS, Slager SL, Witzig TE, Ansell SM, Cerhan JR, Bishop GA, Novak AJ
The Journal of experimental medicine 2010 Nov 22;207(12):2569-79
The Journal of experimental medicine 2010 Nov 22;207(12):2569-79
The novel proapoptotic activity of nonnatural enantiomer of Lentiginosine.
Macchi B, Minutolo A, Grelli S, Cardona F, Cordero FM, Mastino A, Brandi A
Glycobiology 2010 May;20(5):500-6
Glycobiology 2010 May;20(5):500-6
A role for NRAGE in NF-kappaB activation through the non-canonical BMP pathway.
Matluk N, Rochira JA, Karaczyn A, Adams T, Verdi JM
BMC biology 2010 Jan 25;8:7
BMC biology 2010 Jan 25;8:7
Oncogenic K-ras activates p38 to maintain colorectal cancer cell proliferation during MEK inhibition.
van Houdt WJ, de Bruijn MT, Emmink BL, Raats D, Hoogwater FJ, Borel Rinkes IH, Kranenburg O
Cellular oncology : the official journal of the International Society for Cellular Oncology 2010 Jan 1;32(4):245-57
Cellular oncology : the official journal of the International Society for Cellular Oncology 2010 Jan 1;32(4):245-57
Effect of nuclear localization and hydrodynamic delivery-induced cell division on phiC31 integrase activity.
Woodard LE, Hillman RT, Keravala A, Lee S, Calos MP
Gene therapy 2010 Feb;17(2):217-26
Gene therapy 2010 Feb;17(2):217-26
Involvement of VDAC1 and Bcl-2 family of proteins in VacA-induced cytochrome c release and apoptosis of gastric epithelial carcinoma cells.
Lan CH, Sheng JQ, Fang DC, Meng QZ, Fan LL, Huang ZR
Journal of digestive diseases 2010 Feb;11(1):43-9
Journal of digestive diseases 2010 Feb;11(1):43-9
Expression of TAU in insulin-secreting cells and its interaction with the calcium-binding protein secretagogin.
Maj M, Gartner W, Ilhan A, Neziri D, Attems J, Wagner L
The Journal of endocrinology 2010 Apr;205(1):25-36
The Journal of endocrinology 2010 Apr;205(1):25-36
Oncogenic KRAS sensitises colorectal tumour cells to chemotherapy by p53-dependent induction of Noxa.
de Bruijn MT, Raats DA, Hoogwater FJ, van Houdt WJ, Cameron K, Medema JP, Borel Rinkes IH, Kranenburg O
British journal of cancer 2010 Apr 13;102(8):1254-64
British journal of cancer 2010 Apr 13;102(8):1254-64
Neuropilin-1 is essential for enhanced VEGF(165)-mediated vasodilatation in collateral-dependent coronary arterioles of exercise-trained pigs.
Fogarty JA, Delp MD, Muller-Delp JM, Laine GA, Parker JL, Heaps CL
Journal of vascular research 2009;46(2):152-61
Journal of vascular research 2009;46(2):152-61
Analysis of glycosyltransferase expression in metastatic prostate cancer cells capable of rolling activity on microvascular endothelial (E)-selectin.
Barthel SR, Gavino JD, Wiese GK, Jaynes JM, Siddiqui J, Dimitroff CJ
Glycobiology 2008 Oct;18(10):806-17
Glycobiology 2008 Oct;18(10):806-17
HSP90 beta regulates rapsyn turnover and subsequent AChR cluster formation and maintenance.
Luo S, Zhang B, Dong XP, Tao Y, Ting A, Zhou Z, Meixiong J, Luo J, Chiu FC, Xiong WC, Mei L
Neuron 2008 Oct 9;60(1):97-110
Neuron 2008 Oct 9;60(1):97-110
LRP4 serves as a coreceptor of agrin.
Zhang B, Luo S, Wang Q, Suzuki T, Xiong WC, Mei L
Neuron 2008 Oct 23;60(2):285-97
Neuron 2008 Oct 23;60(2):285-97
Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis.
Heazlewood CK, Cook MC, Eri R, Price GR, Tauro SB, Taupin D, Thornton DJ, Png CW, Crockford TL, Cornall RJ, Adams R, Kato M, Nelms KA, Hong NA, Florin TH, Goodnow CC, McGuckin MA
PLoS medicine 2008 Mar 4;5(3):e54
PLoS medicine 2008 Mar 4;5(3):e54
Inhibition of Raf-1 alters multiple downstream pathways to induce pancreatic beta-cell apoptosis.
Alejandro EU, Johnson JD
The Journal of biological chemistry 2008 Jan 25;283(4):2407-17
The Journal of biological chemistry 2008 Jan 25;283(4):2407-17
CDDO-imidazolide mediated inhibition of malignant cell growth in Waldenström macroglobulinemia.
Elsawa SF, Novak AJ, Grote D, Konopleva M, Andreeff M, Witzig TE, Ansell SM
Leukemia research 2008 Dec;32(12):1895-902
Leukemia research 2008 Dec;32(12):1895-902
Glucose and endoplasmic reticulum calcium channels regulate HIF-1beta via presenilin in pancreatic beta-cells.
Dror V, Kalynyak TB, Bychkivska Y, Frey MH, Tee M, Jeffrey KD, Nguyen V, Luciani DS, Johnson JD
The Journal of biological chemistry 2008 Apr 11;283(15):9909-16
The Journal of biological chemistry 2008 Apr 11;283(15):9909-16
The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor.
Greer EL, Oskoui PR, Banko MR, Maniar JM, Gygi MP, Gygi SP, Brunet A
The Journal of biological chemistry 2007 Oct 12;282(41):30107-19
The Journal of biological chemistry 2007 Oct 12;282(41):30107-19
Conditional neuronal simian virus 40 T antigen expression induces Alzheimer-like tau and amyloid pathology in mice.
Park KH, Hallows JL, Chakrabarty P, Davies P, Vincent I
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007 Mar 14;27(11):2969-78
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007 Mar 14;27(11):2969-78
Inhibition of glycogen synthase kinase-3 activity leads to epigenetic silencing of nuclear factor kappaB target genes and induction of apoptosis in chronic lymphocytic leukemia B cells.
Ougolkov AV, Bone ND, Fernandez-Zapico ME, Kay NE, Billadeau DD
Blood 2007 Jul 15;110(2):735-42
Blood 2007 Jul 15;110(2):735-42
OSU-03012, a novel celecoxib derivative, is cytotoxic to myeloma cells and acts through multiple mechanisms.
Zhang S, Suvannasankha A, Crean CD, White VL, Johnson A, Chen CS, Farag SS
Clinical cancer research : an official journal of the American Association for Cancer Research 2007 Aug 15;13(16):4750-8
Clinical cancer research : an official journal of the American Association for Cancer Research 2007 Aug 15;13(16):4750-8
Effect of a vascular endothelial growth factor (VEGF) inhibitory treatment on the folliculogenesis and ovarian apoptosis in gonadotropin-treated prepubertal rats.
Abramovich D, Parborell F, Tesone M
Biology of reproduction 2006 Sep;75(3):434-41
Biology of reproduction 2006 Sep;75(3):434-41
Interleukin-10 anti-inflammatory response to Borrelia burgdorferi, the agent of Lyme disease: a possible role for suppressors of cytokine signaling 1 and 3.
Dennis VA, Jefferson A, Singh SR, Ganapamo F, Philipp MT
Infection and immunity 2006 Oct;74(10):5780-9
Infection and immunity 2006 Oct;74(10):5780-9
Sulindac independently modulates extracellular signal-regulated kinase 1/2 and cyclic GMP-dependent protein kinase signaling pathways.
Rice PL, Peters SL, Beard KS, Ahnen DJ
Molecular cancer therapeutics 2006 Mar;5(3):746-54
Molecular cancer therapeutics 2006 Mar;5(3):746-54
Bone morphogenetic protein-2 induces proinflammatory endothelial phenotype.
Csiszar A, Ahmad M, Smith KE, Labinskyy N, Gao Q, Kaley G, Edwards JG, Wolin MS, Ungvari Z
The American journal of pathology 2006 Feb;168(2):629-38
The American journal of pathology 2006 Feb;168(2):629-38
Deficiency in the catalytic subunit of DNA-dependent protein kinase causes down-regulation of ATM.
Peng Y, Woods RG, Beamish H, Ye R, Lees-Miller SP, Lavin MF, Bedford JS
Cancer research 2005 Mar 1;65(5):1670-7
Cancer research 2005 Mar 1;65(5):1670-7
Quantitative protein expression analysis of CLL B cells from mutated and unmutated IgV(H) subgroups using acid-cleavable isotope-coded affinity tag reagents.
Barnidge DR, Jelinek DF, Muddiman DC, Kay NE
Journal of proteome research 2005 Jul-Aug;4(4):1310-7
Journal of proteome research 2005 Jul-Aug;4(4):1310-7
Role of homologous recombination in the alpha-particle-induced bystander effect for sister chromatid exchanges and chromosomal aberrations.
Nagasawa H, Peng Y, Wilson PF, Lio YC, Chen DJ, Bedford JS, Little JB
Radiation research 2005 Aug;164(2):141-7
Radiation research 2005 Aug;164(2):141-7
Role of homologous recombination in the alpha-particle-induced bystander effect for sister chromatid exchanges and chromosomal aberrations.
Nagasawa H, Peng Y, Wilson PF, Lio YC, Chen DJ, Bedford JS, Little JB
Radiation research 2005 Aug;164(2):141-7
Radiation research 2005 Aug;164(2):141-7
RPE65 is the isomerohydrolase in the retinoid visual cycle.
Moiseyev G, Chen Y, Takahashi Y, Wu BX, Ma JX
Proceedings of the National Academy of Sciences of the United States of America 2005 Aug 30;102(35):12413-8
Proceedings of the National Academy of Sciences of the United States of America 2005 Aug 30;102(35):12413-8
Antinuclear antigen B cells that down-regulate surface B cell receptor during development to mature, follicular phenotype do not display features of anergy in vitro.
Liu X, Manser T
Journal of immunology (Baltimore, Md. : 1950) 2005 Apr 15;174(8):4505-15
Journal of immunology (Baltimore, Md. : 1950) 2005 Apr 15;174(8):4505-15
Antinuclear antigen B cells that down-regulate surface B cell receptor during development to mature, follicular phenotype do not display features of anergy in vitro.
Liu X, Manser T
Journal of immunology (Baltimore, Md. : 1950) 2005 Apr 15;174(8):4505-15
Journal of immunology (Baltimore, Md. : 1950) 2005 Apr 15;174(8):4505-15
Differential display polymerase chain reaction reveals increased expression of striatal rat glia-derived nexin following chronic clozapine treatment.
Chong VZ, Costain W, Marriott J, Sindwani S, Knauer DJ, Wang JF, Young LT, MacCrimmon D, Mishra RK
The pharmacogenomics journal 2004;4(6):379-87
The pharmacogenomics journal 2004;4(6):379-87
Involvement of raft-like plasma membrane domains of Entamoeba histolytica in pinocytosis and adhesion.
Laughlin RC, McGugan GC, Powell RR, Welter BH, Temesvari LA
Infection and immunity 2004 Sep;72(9):5349-57
Infection and immunity 2004 Sep;72(9):5349-57
Oxidant stress in kidneys of spontaneously hypertensive rats involves both oxidase overexpression and loss of extracellular superoxide dismutase.
Adler S, Huang H
American journal of physiology. Renal physiology 2004 Nov;287(5):F907-13
American journal of physiology. Renal physiology 2004 Nov;287(5):F907-13
Degradation of NF-kappa B in T cells by gangliosides expressed on renal cell carcinomas.
Thornton MV, Kudo D, Rayman P, Horton C, Molto L, Cathcart MK, Ng C, Paszkiewicz-Kozik E, Bukowski R, Derweesh I, Tannenbaum CS, Finke JH
Journal of immunology (Baltimore, Md. : 1950) 2004 Mar 15;172(6):3480-90
Journal of immunology (Baltimore, Md. : 1950) 2004 Mar 15;172(6):3480-90
Degradation of NF-kappa B in T cells by gangliosides expressed on renal cell carcinomas.
Thornton MV, Kudo D, Rayman P, Horton C, Molto L, Cathcart MK, Ng C, Paszkiewicz-Kozik E, Bukowski R, Derweesh I, Tannenbaum CS, Finke JH
Journal of immunology (Baltimore, Md. : 1950) 2004 Mar 15;172(6):3480-90
Journal of immunology (Baltimore, Md. : 1950) 2004 Mar 15;172(6):3480-90
Inhibition of insulin synthesis by cyproheptadine: effects on translation.
Hawkins BS, Fischer LJ
Toxicological sciences : an official journal of the Society of Toxicology 2004 Jun;79(2):258-65
Toxicological sciences : an official journal of the Society of Toxicology 2004 Jun;79(2):258-65
Reduced release of nitric oxide to shear stress in mesenteric arteries of aged rats.
Sun D, Huang A, Yan EH, Wu Z, Yan C, Kaminski PM, Oury TD, Wolin MS, Kaley G
American journal of physiology. Heart and circulatory physiology 2004 Jun;286(6):H2249-56
American journal of physiology. Heart and circulatory physiology 2004 Jun;286(6):H2249-56
Oxidant stress leads to impaired regulation of renal cortical oxygen consumption by nitric oxide in the aging kidney.
Adler S, Huang H, Wolin MS, Kaminski PM
Journal of the American Society of Nephrology : JASN 2004 Jan;15(1):52-60
Journal of the American Society of Nephrology : JASN 2004 Jan;15(1):52-60
Oxidant stress leads to impaired regulation of renal cortical oxygen consumption by nitric oxide in the aging kidney.
Adler S, Huang H, Wolin MS, Kaminski PM
Journal of the American Society of Nephrology : JASN 2004 Jan;15(1):52-60
Journal of the American Society of Nephrology : JASN 2004 Jan;15(1):52-60
Modulation of nuclear factor-kappa B activity by indomethacin influences A beta levels but not A beta precursor protein metabolism in a model of Alzheimer's disease.
Sung S, Yang H, Uryu K, Lee EB, Zhao L, Shineman D, Trojanowski JQ, Lee VM, Praticò D
The American journal of pathology 2004 Dec;165(6):2197-206
The American journal of pathology 2004 Dec;165(6):2197-206
Modulation of nuclear factor-kappa B activity by indomethacin influences A beta levels but not A beta precursor protein metabolism in a model of Alzheimer's disease.
Sung S, Yang H, Uryu K, Lee EB, Zhao L, Shineman D, Trojanowski JQ, Lee VM, Praticò D
The American journal of pathology 2004 Dec;165(6):2197-206
The American journal of pathology 2004 Dec;165(6):2197-206
Imatinib mesylate inhibits T-cell proliferation in vitro and delayed-type hypersensitivity in vivo.
Dietz AB, Souan L, Knutson GJ, Bulur PA, Litzow MR, Vuk-Pavlovic S
Blood 2004 Aug 15;104(4):1094-9
Blood 2004 Aug 15;104(4):1094-9
Antiangiogenic and proapoptotic effects of dietary restriction on experimental mouse and human brain tumors.
Mukherjee P, Abate LE, Seyfried TN
Clinical cancer research : an official journal of the American Association for Cancer Research 2004 Aug 15;10(16):5622-9
Clinical cancer research : an official journal of the American Association for Cancer Research 2004 Aug 15;10(16):5622-9
Genome-wide discovery of loci influencing chemotherapy cytotoxicity.
Watters JW, Kraja A, Meucci MA, Province MA, McLeod HL
Proceedings of the National Academy of Sciences of the United States of America 2004 Aug 10;101(32):11809-14
Proceedings of the National Academy of Sciences of the United States of America 2004 Aug 10;101(32):11809-14
Direct reprobing with anti-beta-actin antibody as an internal control for western blotting analysis.
Liao J, Xu X, Wargovich MJ
BioTechniques 2000 Feb;28(2):216-8
BioTechniques 2000 Feb;28(2):216-8
Beta-actin specific monoclonal antibody.
Gimona M, Vandekerckhove J, Goethals M, Herzog M, Lando Z, Small JV
Cell motility and the cytoskeleton 1994;27(2):108-16
Cell motility and the cytoskeleton 1994;27(2):108-16
Actin isoform compartments in chicken gizzard smooth muscle cells.
North AJ, Gimona M, Lando Z, Small JV
Journal of cell science 1994 Mar;107 ( Pt 3):445-55
Journal of cell science 1994 Mar;107 ( Pt 3):445-55
Calponin is localised in both the contractile apparatus and the cytoskeleton of smooth muscle cells.
North AJ, Gimona M, Cross RA, Small JV
Journal of cell science 1994 Mar;107 ( Pt 3):437-44
Journal of cell science 1994 Mar;107 ( Pt 3):437-44
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Supportive validation
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- Western Blot: beta-Actin Antibody (AC-15) [NB600-501] - beta-Actin expression in CHO, GC-1, HeLa, Cos-7 and SH-SY5Y cell lysates using anti-beta-Actin antibody. The primary antibody was used at a dilution of 1:10,000 for 1 hour. Image from verified customer review.
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- Western Blot: beta-Actin Antibody (AC-15) [NB600-501] - Whole cell extract of human fibroblasts was separated on SDS-PAGE and blotted with Monoclonal Anti-beta-Actin. The antibody was developed with Goat Anti-Mouse IgG, Peroxidase conjugate and AEC substrate. Lanes A: Antibody dilution 1:5,000 B: Negative control (only secondary antibody).
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- Western Blot: beta-Actin Antibody (AC-15) [NB600-501] - MCDK cells induced with C22H24N2O8 to control the expression of the gene of interest. Beta-actin blocking confirms the albumin assay showing that an equal amount of lysate was loaded in each lane.
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- Western Blot: beta-Actin Antibody (AC-15) [NB600-501] - beta-Actin expression in human cell lines (Caco-2, T84, HCT116, HT29, DU145, BPH1, HeLa). Image from verified customer review.
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- Western Blot: beta-Actin Antibody (AC-15) [NB600-501] - Analysis of beta-Actin in bovine whole skeletal muscle lysate. Image from verified customer review.
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- Western Blot: beta-Actin Antibody (AC-15) [NB600-501] - Beta-Actin expression in Fibroblast Hs68 cell lysate using anti-beta-Actin antibody. Image from verified customer review.
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- Western Blot: beta-Actin Antibody (AC-15) [NB600-501] - beta-Actin expression in human glioma cells using anti-beta-Actin antibody. Image from verified customer review.
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- Simple Western: beta-Actin Antibody (AC-15) [NB600-501] - Analysis using the HRP conjugate of NB600-501. Image shows a specific band for Beta-Actin in 0.2 mg/mL of Hela, MCF-7, SH-SY5Y, & Jurkat lysate(s). This experiment was performed under reducing conditions using the 12-230 kDa separation system. * Non-specific interaction with the 230 kDa Simple Western standard may be seen with this antibody.
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- Western Blot: beta-Actin Antibody (AC-15) [NB600-501] - Analysis of beta-actin in NIH/3T3 and HEK293T cells using HRP conjugated beta-actin antibody (Cat# NB600-501H). Image from verified customer review.
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- Western Blot: beta-Actin Antibody (AC-15) [NB600-501] - HEK293T cells transfected with Niaph virus Matrix Protein, expression 24h later. This image was submitted via customer review.
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- Simple Western: beta-Actin Antibody (AC-15) [NB600-501] - Analysis using the HRP conjugate of NB600-501. Electropherogram image(s) of corresponding Simple Western lane view. Beta-Actin antibody was used at 1:500 dilution on Hela, MCF-7, SH-SY5Y, & Jurkat lysate(s).
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- Western Blot: beta-Actin Antibody (AC-15) [NB600-501] - MMP-11 expression in oral cancer cell lines and the MMP-11 knockdown in SCC9 cells reduce cell migration. Western blot analysis showing the expression of MMP-11 protein in five oral cancer cell lines. Beta-Actin is included as a loading control. Image collected and cropped by CiteAb from the following publication (http://dx.plos.org/10.1371/journal.pone.0113129), licensed under a CC-BY licence.
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- Western Blot: beta-Actin Antibody (AC-15) [NB600-501] - GFAP and IL-6 are elevated in cultures of spinal cord compared to cortical astrocytes. ((G, H) Analysis of protein homogenates from brain or spinal cord astrocyte cultures also demonstrated higher levels of GFAP expression, but no differences in ALDH1L1. Beta-Actin is included as a loading control. Image collected and cropped by CiteAb from the following publication (http://dx.plos.org/10.1371/journal.pone.0180697), licensed under a CC-BY licence.
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- Western Blot: beta-Actin Antibody (AC-15) [NB600-501] - HSP90 and HSP70 interact with PABPN1. Interaction of PABPN1 with HSP90. Lysates from HEK293 cells transfected with Flag-HSP90 and GFP-tagged A17-PABPN1 were immunoprecipitated with an anti-Flag antibody. Immunoprecipitates (IP) were analyzed by Western blot (IB).Beta-Actin is included as a loading control. Image collected and cropped by CiteAb from the following publication (http://dx.plos.org/10.1371/journal.pone.0138936), licensed under a CC-BY licence.
Supportive validation
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- Immunohistochemistry: beta-Actin Antibody (AC-15) [NB600-501] - Breast, Epithelium 40X.
Supportive validation
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- Flow Cytometry: beta-Actin Antibody (AC-15) [NB600-501] - Analysis of HeLa cells using mouse Monoclonal beta-Actin antibody (orange) and Isotype control antibody (blue).
