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- Antibody Data
- Antigen structure
- References [146]
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- Product number
- HRP-60008 - Provider product page
- Provider
- Proteintech Group
- Product name
- beta actin antibody
- Antibody type
- Monoclonal
- Description
- Beta Actin antibody (Cat. #HRP-60008) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat, zebrafish, plant and has been validated for the following applications: WB.
- Reactivity
- Human, Mouse, Rat, Zebrafish
- Host
- Mouse
- Conjugate
- Horseradish Peroxidase
- Isotype
- IgM
- Vial size
- 100ul
Submitted references CDK15 promotes colorectal cancer progression via phosphorylating PAK4 and regulating β-catenin/ MEK-ERK signaling pathway.
Effect of the Photocatalyst under Visible Light Irradiation in SARS-CoV-2 Stability on an Abiotic Surface.
Deciphering the effects of PYCR1 on cell function and its associated mechanism in hepatocellular carcinoma.
Deletion of p16 accelerates fracture healing in geriatric mice.
Novel LAT Pathogenic Variants in a POI Family and Its Role in the Ovary.
Overexpression of GmGAMYB Accelerates the Transition to Flowering and Increases Plant Height in Soybean.
Increased SPC24 in prostatic diseases and diagnostic value of SPC24 and its interacting partners in prostate cancer.
The kidney hepcidin/ferroportin axis controls iron reabsorption and determines the magnitude of kidney and systemic iron overload.
Glial IL-33 signaling through an ST2-to-CXCL12 pathway in the spinal cord contributes to morphine-induced hyperalgesia and tolerance.
Reversible dysregulation of renal circadian rhythm in lupus nephritis.
TAZ maintains telomere length in TNBC cells by mediating Rad51C expression.
Hydrogen peroxide induces progranulin expression to control neurite outgrowth in HT22 cells.
Generation of a homozygous LRPAP1 knockout human embryonic stem cell line (FDCHDPe009-B) by CRISPR/Cas9 system.
African pygmy hedgehog adenovirus: Virus replication, virus-induced cytopathogenesis and activation of mitogen-activated protein kinase signaling pathways in infected MDCK cells.
The neuronal ceroid lipofuscinosis-related protein CLN8 regulates endo-lysosomal dynamics and dendritic morphology.
Loss of lncRNA SNHG8 promotes epithelial-mesenchymal transition by destabilizing CDH1 mRNA.
Cancer-associated dynamics and potential regulators of intronic polyadenylation revealed by IPAFinder using standard RNA-seq data.
The effects of bathing in neutral bicarbonate ion water.
Whole exome sequencing identified a rare WT1 loss-of-function variant in a non-syndromic POI patient.
Roles for ADAM17 in TNF-R1 Mediated Cell Death and Survival in Human U937 and Jurkat Cells.
11βHSD2 Efficacy in Preventing Transcriptional Activation of the Mineralocorticoid Receptor by Corticosterone.
Acupuncture Can Play an Antidepressant Role by Regulating the Intestinal Microbes and Neurotransmitters in a Rat Model of Depression.
FTY720 Modulates Microglia Toward Anti-inflammatory Phenotype by Suppressing Autophagy via STAT1 Pathway.
The antidepressant and anxiolytic effect of GPER on translocator protein (TSPO) via protein kinase a (PKA) signaling in menopausal female rats.
Tea polyphenols inhibit the growth and virulence of ETEC K88.
Deletion of the SARS-CoV-2 Spike Cytoplasmic Tail Increases Infectivity in Pseudovirus Neutralization Assays.
lncRNA PCAT6 facilitates cell proliferation and invasion via regulating the miR-326/hnRNPA2B1 axis in liver cancer.
Lipid-injured hepatocytes release sOPN to improve macrophage migration via CD44 engagement and pFak-NFκB signaling.
Novel Mutations in X-Linked, USP26-Induced Asthenoteratozoospermia and Male Infertility.
Restriction of Manganese Intake Prevents the Onset of Brain Manganese Overload in Zip14-/- Mice.
Centrosomal P4.1-associated protein (CPAP) positively regulates endocytic vesicular transport and lysosome targeting of EGFR.
Knockout analysis of Rab6 effector proteins revealed the role of VPS52 in the secretory pathway.
Assessment of the Oral Delivery of a Myelin Basic Protein Gene Promoter with Antiapoptotic bcl-xL (pMBP-bcl-xL) DNA by Cyclic Peptide Nanotubes with Two Aspect Ratios and Its Biodistribution in the Brain and Spinal Cord.
A heterozygous hypomorphic mutation of Fanca causes impaired follicle development and subfertility in female mice.
A novel prognostic model based on four circulating miRNA in diffuse large B-cell lymphoma: implications for the roles of MDSC and Th17 cells in lymphoma progression.
Adaptive mutations promote hepatitis C virus assembly by accelerating core translocation to the endoplasmic reticulum.
NT157 Inhibits HCC Migration via Downregulating the STAT3/Jab1 Signaling Pathway.
Significance of MR/OPN/HMGB1 axis in NAFLD-associated hepatic fibrogenesis.
Involvement of GPX4 in irisin's protection against ischemia reperfusion-induced acute kidney injury.
Deleterious variants in X-linked CFAP47 induce asthenoteratozoospermia and primary male infertility.
CircNR3C2 promotes HRD1-mediated tumor-suppressive effect via sponging miR-513a-3p in triple-negative breast cancer.
Extending the Calpain-Cathepsin Hypothesis to the Neurovasculature: Protection of Brain Endothelial Cells and Mice from Neurotrauma.
Isoliquiritigenin attenuates septic acute kidney injury by regulating ferritinophagy-mediated ferroptosis.
Environmental allergens house dust mite-induced asthma is associated with ferroptosis in the lungs.
Expression pattern of mitogen-activated protein kinase kinase 4 and regulation to antibacterial factor ABF-1/2 in response to bacterial challenge from Artemia parthenogenetica.
Up-regulation of heme oxygenase-1 by celastrol alleviates oxidative stress and vascular calcification in chronic kidney disease.
Wu-5, a novel USP10 inhibitor, enhances crenolanib-induced FLT3-ITD-positive AML cell death via inhibiting FLT3 and AMPK pathways.
Haploinsufficiency in non-homologous end joining factor 1 induces ovarian dysfunction in humans and mice.
Loss of CPAP causes sustained EGFR signaling and epithelial-mesenchymal transition in oral cancer.
Quercetin Suppresses Apoptosis and Attenuates Intervertebral Disc Degeneration via the SIRT1-Autophagy Pathway.
miR-4270 regulates cell proliferation and apoptosis in patients with Sertoli cell-only syndrome by targeting GADD45A and inactivating the NOTCH signaling pathway.
Overexpression of Platelet-Derived Growth Factor Receptor Α D842V Mutants Prevents Liver Regeneration and Chemically Induced Hepatocarcinogenesis via Inhibition of MET and EGFR.
Cytokine Signature Induced by SARS-CoV-2 Spike Protein in a Mouse Model.
Mechanism and Molecular Network of RBM8A-Mediated Regulation of Oxaliplatin Resistance in Hepatocellular Carcinoma.
Fetal liver hepcidin secures iron stores in utero.
The common K333Q polymorphism in long-chain acyl-CoA dehydrogenase (LCAD) reduces enzyme stability and function.
Involvement of kindlin-2 in irisin's protection against ischaemia reperfusion-induced liver injury in high-fat diet-fed mice.
Lithium chloride ameliorated spatial cognitive impairment through activating mTOR phosphorylation and inhibiting excessive autophagy in the repeated cerebral ischemia-reperfusion mouse model.
Wnt/β-Catenin Signaling Axis Is Required for TFEB-Mediated Gastric Cancer Metastasis and Epithelial-Mesenchymal Transition.
Transmembrane protein 106C promotes the development of hepatocellular carcinoma.
Suppressor of Ty 16 promotes lung cancer malignancy and is negatively regulated by miR-1227-5p.
Hypoxia Alters the Response to Anti-EGFR Therapy by Regulating EGFR Expression and Downstream Signaling in a DNA Methylation-Specific and HIF-Dependent Manner.
Down-regulation of miR-3068-3p enhances kcnip4-regulated A-type potassium current to protect against glutamate-induced excitotoxicity.
Combination therapy of BCR-ABL-positive B cell acute lymphoblastic leukemia by tyrosine kinase inhibitor dasatinib and c-JUN N-terminal kinase inhibition.
HIGD2A is Required for Assembly of the COX3 Module of Human Mitochondrial Complex IV.
Calcium-Inducible MAPK/AP-1 Signaling Drives Semaphorin 3A Expression in Normal Human Epidermal Keratinocytes.
The impact of MCM6 on hepatocellular carcinoma in a Southern Chinese Zhuang population.
Irisin reverses intestinal epithelial barrier dysfunction during intestinal injury via binding to the integrin αVβ5 receptor.
TRB3 interacts with ERK and JNK and contributes to the proliferation, apoptosis, and migration of lung adenocarcinoma cells.
MicroRNA-188 regulates aging-associated metabolic phenotype.
Osthole delays hepatocarcinogenesis in mice by suppressing AKT/FASN axis and ERK phosphorylation.
Blockade of JAK2 protects mice against hypoxia-induced pulmonary arterial hypertension by repressing pulmonary arterial smooth muscle cell proliferation.
Lipopolysaccharide-Elicited Systemic Inflammation Induces Selective Vulnerability of Cerebral Cortex and Striatum of Developing Glutaryl-CoA Dehydrogenase Deficient (Gcdh-/-) Mice to Oxidative Stress.
Diagnostic and prognostic value of MCM3 and its interacting proteins in hepatocellular carcinoma.
Targeted Stat2 deletion in conventional dendritic cells impairs CTL responses but does not affect antibody production.
PTPN2 regulates the activation of KRAS and plays a critical role in proliferation and survival of KRAS-driven cancer cells.
Ammonia-Induced Glial-Inflammaging.
Girdin interaction with vimentin induces EMT and promotes the growth and metastasis of pancreatic ductal adenocarcinoma.
Hydroxysafflor yellow A induces autophagy in human liver cancer cells by regulating Beclin 1 and ERK expression.
Stabilization of PTGES by deubiquitinase USP9X promotes metastatic features of lung cancer via PGE2 signaling.
Dysregulated ENPP1 increases the malignancy of human lung cancer by inducing epithelial-mesenchymal transition phenotypes and stem cell features.
Comparative Effect of Aqueous and Methanolic Bupleuri Radix Extracts on Hepatic Uptake of High-Density Lipoprotein and Identification of the Potential Target in HFD-Fed Mice.
Spinal IL-33/ST2 signaling mediates chronic itch in mice through the astrocytic JAK2-STAT3 cascade.
HNF‑4α downregulation promotes tumor migration and invasion by regulating E‑cadherin in renal cell carcinoma.
The fatty acid oxidation enzyme long-chain acyl-CoA dehydrogenase can be a source of mitochondrial hydrogen peroxide.
Curcumin suppresses osteogenesis by inducing miR-126a-3p and subsequently suppressing the WNT/LRP6 pathway.
Fate-mapping post-hypoxic tumor cells reveals a ROS-resistant phenotype that promotes metastasis.
SPRY4 is responsible for pathogenesis of adolescent idiopathic scoliosis by contributing to osteogenic differentiation and melatonin response of bone marrow-derived mesenchymal stem cells.
Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease.
Vascular Endothelial Growth Factor A Signaling Promotes Spinal Central Sensitization and Pain-related Behaviors in Female Rats with Bone Cancer.
Adaptor protein APPL1 coordinates HDAC3 to modulate brown adipose tissue thermogenesis in mice.
CD1d highly expressed on DCs reduces lung tumor burden by enhancing antitumor immunity.
Downregulated expression of CFHL1 is associated with unfavorable prognosis in postoperative patients with hepatocellular carcinoma.
TRPV1 mediates astrocyte activation and interleukin-1β release induced by hypoxic ischemia (HI).
MiR155 sensitized B-lymphoma cells to anti-PD-L1 antibody via PD-1/PD-L1-mediated lymphoma cell interaction with CD8+T cells.
The intestinal metal transporter ZIP14 maintains systemic manganese homeostasis.
Manganese Uptake by A549 Cells is Mediated by Both ZIP8 and ZIP14.
ITGA6 and RPSA synergistically promote pancreatic cancer invasion and metastasis via PI3K and MAPK signaling pathways.
The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance.
The synergistic effect of NOD2 and TLR4 on the activation of autophagy in human submandibular gland inflammation.
Anti-MET VHH Pool Overcomes MET-Targeted Cancer Therapeutic Resistance.
Triptolide interferes with XRCC1/PARP1-mediated DNA repair and confers sensitization of triple-negative breast cancer cells to cisplatin.
G-1 exhibit antidepressant effect, increase of hippocampal ERs expression and improve hippocampal redox status in aged female rats.
AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition.
Codelivery of DOX and siRNA by folate-biotin-quaternized starch nanoparticles for promoting synergistic suppression of human lung cancer cells.
miR-942 promotes tumor migration, invasion, and angiogenesis by regulating EMT via BARX2 in non-small-cell lung cancer.
Rare variants in FANCA induce premature ovarian insufficiency.
Bi-allelic Mutations in TTC29 Cause Male Subfertility with Asthenoteratospermia in Humans and Mice.
Shisa3 brakes resistance to EGFR-TKIs in lung adenocarcinoma by suppressing cancer stem cell properties.
FOXP3 pathogenic variants cause male infertility through affecting the proliferation and apoptosis of human spermatogonial stem cells.
Palmitoylation is required for TNF-R1 signaling.
KMT2D deficiency enhances the anti-cancer activity of L48H37 in pancreatic ductal adenocarcinoma.
Adeno-associated virus 2 bound to its cellular receptor AAVR.
Downregulation of nucleolar and spindle-associated protein 1 expression suppresses liver cancer cell function.
The Alisma and Rhizoma decoction abates nonalcoholic steatohepatitis-associated liver injuries in mice by modulating oxidative stress and autophagy.
Iron-dependent CDK1 activity promotes lung carcinogenesis via activation of the GP130/STAT3 signaling pathway.
Development of an Infectious Cell Culture System for Hepatitis C Virus Genotype 6a Clinical Isolate Using a Novel Strategy and Its Sensitivity to Direct-Acting Antivirals.
Chronic restraint stress disturbs meiotic resumption through APC/C-mediated cyclin B1 excessive degradation in mouse oocytes.
Isoliquiritigenin attenuates LPS-induced AKI by suppression of inflammation involving NF-κB pathway.
miR-193a inhibits osteogenic differentiation of bone marrow-derived stroma cell via targeting HMGB1.
Interfilament interaction between IMPDH and CTPS cytoophidia.
Inhibition of the aryl hydrocarbon receptor/polyamine biosynthesis axis suppresses multiple myeloma.
Computational and biochemical studies of isothiocyanates as inhibitors of proteasomal cysteine deubiquitinases in human cancer cells.
Natural killer T cell ligand alpha-galactosylceramide protects against gut ischemia reperfusion-induced organ injury in mice.
[6]-Gingerol enhances the radiosensitivity of gastric cancer via G2/M phase arrest and apoptosis induction.
Ubiquitin-specific protease 15 promotes tumor cell invasion and proliferation in glioblastoma.
Homeobox B3 promotes tumor cell proliferation and invasion in glioblastoma.
Expression of nerve growth factor carried by pseudotyped lentivirus improves neuron survival and cognitive functional recovery of post-ischemia in rats.
Identifying the SUMO1 modification of FAM122A leading to the degradation of PP2A-Cα by ubiquitin-proteasome system.
Vitexin reduces epilepsy after hypoxic ischemia in the neonatal brain via inhibition of NKCC1.
Gelofusine Attenuates Tubulointerstitial Injury Induced by cRGD-Conjugated siRNA by Regulating the TLR3 Signaling Pathway.
Loss of the ubiquitin conjugating enzyme UBE2E3 induces cellular senescence.
Lipopolysaccharide (LPS)-mediated priming of toll-like receptor 4 enhances oxidant-induced prostaglandin E2 biosynthesis in primary murine macrophages.
FSTL1 suppresses tumor cell proliferation, invasion and survival in non-small cell lung cancer.
Transcriptional regulation of P63 on the apoptosis of male germ cells and three stages of spermatogenesis in mice.
The Significant Role of c-Abl Kinase in Barrier Altering Agonists-mediated Cytoskeletal Biomechanics.
Identification of a cellularly active SIRT6 allosteric activator.
PTEN Regulates Nonhomologous End Joining By Epigenetic Induction of NHEJ1/XLF.
Adaptive mutation F772S-enhanced p7-NS4A cooperation facilitates the assembly and release of hepatitis C virus and is associated with lipid droplet enlargement.
4-Hydroxy-7-oxo-5-heptenoic Acid Lactone Is a Potent Inducer of the Complement Pathway in Human Retinal Pigmented Epithelial Cells.
HMGB1-induced autophagy facilitates hepatic stellate cells activation: a new pathway in liver fibrosis.
Twinfilin 1 enhances milk bio-synthesis and proliferation of bovine mammary epithelial cells via the mTOR signaling pathway.
Critical roles of CTP synthase N-terminal in cytoophidium assembly.
Astragalus polysaccharide ameliorates H2O2-induced human umbilical vein endothelial cell injury.
DNMT1-maintained hypermethylation of Krüppel-like factor 5 involves in the progression of clear cell renal cell carcinoma.
Progranulin derived engineered protein Atsttrin suppresses TNF-α-mediated inflammation in intervertebral disc degenerative disease.
Huang C, Du R, Jia X, Liu K, Qiao Y, Wu Q, Yao N, Yang L, Zhou L, Liu X, Xiang P, Xin M, Wang Y, Chen X, Kim DJ, Dong Z, Li X
Cell death and differentiation 2022 Jan;29(1):14-27
Cell death and differentiation 2022 Jan;29(1):14-27
Effect of the Photocatalyst under Visible Light Irradiation in SARS-CoV-2 Stability on an Abiotic Surface.
Uema M, Yonemitsu K, Momose Y, Ishii Y, Tateda K, Inoue T, Asakura H
Biocontrol science 2021;26(2):119-125
Biocontrol science 2021;26(2):119-125
Deciphering the effects of PYCR1 on cell function and its associated mechanism in hepatocellular carcinoma.
Xu Y, Zuo W, Wang X, Zhang Q, Gan X, Tan N, Jia W, Liu J, Li Z, Zhou B, Zhao D, Xie Z, Tan Y, Zheng S, Liu C, Li H, Chen Z, Yang X, Huang Z
International journal of biological sciences 2021;17(9):2223-2239
International journal of biological sciences 2021;17(9):2223-2239
Deletion of p16 accelerates fracture healing in geriatric mice.
Ding Q, Liu H, Liu L, Ma C, Qin H, Wei Y, Ren Y
American journal of translational research 2021;13(10):11107-11125
American journal of translational research 2021;13(10):11107-11125
Novel LAT Pathogenic Variants in a POI Family and Its Role in the Ovary.
Chu K, He Y, Li Z, Jiang Z, Wang L, Ji Y, Wang X, Pang W, Sun N, Yang F, Li W
Frontiers in genetics 2021;12:764160
Frontiers in genetics 2021;12:764160
Overexpression of GmGAMYB Accelerates the Transition to Flowering and Increases Plant Height in Soybean.
Yang X, Li X, Shan J, Li Y, Zhang Y, Wang Y, Li W, Zhao L
Frontiers in plant science 2021;12:667242
Frontiers in plant science 2021;12:667242
Increased SPC24 in prostatic diseases and diagnostic value of SPC24 and its interacting partners in prostate cancer.
Chen S, Wang X, Zheng S, Li H, Qin S, Liu J, Jia W, Shao M, Tan Y, Liang H, Song W, Lu S, Liu C, Yang X
Experimental and therapeutic medicine 2021 Sep;22(3):923
Experimental and therapeutic medicine 2021 Sep;22(3):923
The kidney hepcidin/ferroportin axis controls iron reabsorption and determines the magnitude of kidney and systemic iron overload.
Mohammad G, Matakidou A, Robbins PA, Lakhal-Littleton S
Kidney international 2021 Sep;100(3):559-569
Kidney international 2021 Sep;100(3):559-569
Glial IL-33 signaling through an ST2-to-CXCL12 pathway in the spinal cord contributes to morphine-induced hyperalgesia and tolerance.
Hu XM, Yang W, Zhang MT, Du LX, Tian JH, Zhu JY, Chen Y, Hai F, Liu SB, Mao-Ying QL, Chu YX, Zhou H, Wang YQ, Mi WL
Science signaling 2021 Sep 7;14(699):eabe3773
Science signaling 2021 Sep 7;14(699):eabe3773
Reversible dysregulation of renal circadian rhythm in lupus nephritis.
Mishra R, Bethunaickan R, Berthier CC, Yi Z, Strohl JJ, Huerta PT, Zhang W, Davidson A
Molecular medicine (Cambridge, Mass.) 2021 Sep 6;27(1):99
Molecular medicine (Cambridge, Mass.) 2021 Sep 6;27(1):99
TAZ maintains telomere length in TNBC cells by mediating Rad51C expression.
Yang L, Wang B, Jiao X, Zhou C, Chen S, Gao X, Sun W, Song S, Li J, Liu J, Wang Y, Liu P
Breast cancer research : BCR 2021 Sep 6;23(1):89
Breast cancer research : BCR 2021 Sep 6;23(1):89
Hydrogen peroxide induces progranulin expression to control neurite outgrowth in HT22 cells.
Shimoda A, Tanabe T, Sato T, Nedachi T
Bioscience, biotechnology, and biochemistry 2021 Sep 22;85(10):2103-2112
Bioscience, biotechnology, and biochemistry 2021 Sep 22;85(10):2103-2112
Generation of a homozygous LRPAP1 knockout human embryonic stem cell line (FDCHDPe009-B) by CRISPR/Cas9 system.
You J, Xi H, Ma S, Yang XJ, Chen L
Stem cell research 2021 Oct;56:102516
Stem cell research 2021 Oct;56:102516
African pygmy hedgehog adenovirus: Virus replication, virus-induced cytopathogenesis and activation of mitogen-activated protein kinase signaling pathways in infected MDCK cells.
Wen R, Ochiai H, Uchiyama J, Osawa N, Oba M, Katayama Y, Li K, Omatsu T, Tamukai K, Suzuki K, Madarame H, Makino S, Mizutani T
Research in veterinary science 2021 Oct;139:152-158
Research in veterinary science 2021 Oct;139:152-158
The neuronal ceroid lipofuscinosis-related protein CLN8 regulates endo-lysosomal dynamics and dendritic morphology.
Pesaola F, Quassollo G, Venier AC, De Paul AL, Noher I, Bisbal M
Biology of the cell 2021 Oct;113(10):419-437
Biology of the cell 2021 Oct;113(10):419-437
Loss of lncRNA SNHG8 promotes epithelial-mesenchymal transition by destabilizing CDH1 mRNA.
He P, Zhang C, Chen G, Shen S
Science China. Life sciences 2021 Nov;64(11):1858-1867
Science China. Life sciences 2021 Nov;64(11):1858-1867
Cancer-associated dynamics and potential regulators of intronic polyadenylation revealed by IPAFinder using standard RNA-seq data.
Zhao Z, Xu Q, Wei R, Wang W, Ding D, Yang Y, Yao J, Zhang L, Hu YQ, Wei G, Ni T
Genome research 2021 Nov;31(11):2095-2106
Genome research 2021 Nov;31(11):2095-2106
The effects of bathing in neutral bicarbonate ion water.
Yamazaki T, Ushikoshi-Nakayama R, Shakya S, Omagari D, Matsumoto N, Nukuzuma C, Komatsu T, Lee MC, Inoue H, Saito I
Scientific reports 2021 Nov 8;11(1):21789
Scientific reports 2021 Nov 8;11(1):21789
Whole exome sequencing identified a rare WT1 loss-of-function variant in a non-syndromic POI patient.
Wang Y, Chen Q, Zhang F, Yang X, Shang L, Ren S, Pan Y, Zhou Z, Li G, Fang Y, Jin L, Wu Y, Zhang X
Molecular genetics & genomic medicine 2021 Nov 29;:e1820
Molecular genetics & genomic medicine 2021 Nov 29;:e1820
Roles for ADAM17 in TNF-R1 Mediated Cell Death and Survival in Human U937 and Jurkat Cells.
Fritsch J, Frankenheim J, Marischen L, Vadasz T, Troeger A, Rose-John S, Schmidt-Arras D, Schneider-Brachert W
Cells 2021 Nov 10;10(11)
Cells 2021 Nov 10;10(11)
11βHSD2 Efficacy in Preventing Transcriptional Activation of the Mineralocorticoid Receptor by Corticosterone.
Ali Y, Kuppusamy M, Velarde-Miranda C, Gomez-Sanchez CM, Plonczynski M, Gomez-Sanchez CE, Gomez-Sanchez EP
Journal of the Endocrine Society 2021 Nov 1;5(11):bvab146
Journal of the Endocrine Society 2021 Nov 1;5(11):bvab146
Acupuncture Can Play an Antidepressant Role by Regulating the Intestinal Microbes and Neurotransmitters in a Rat Model of Depression.
Li P, Huang W, Yan YN, Cheng W, Liu S, Huang Y, Chen W, Chen YP, Gao Y, Lu W, Xu Y, Meng X
Medical science monitor : international medical journal of experimental and clinical research 2021 May 27;27:e929027
Medical science monitor : international medical journal of experimental and clinical research 2021 May 27;27:e929027
FTY720 Modulates Microglia Toward Anti-inflammatory Phenotype by Suppressing Autophagy via STAT1 Pathway.
Hu ZW, Zhou LQ, Yang S, Chen M, Yu HH, Tao R, Wu LJ, Wang W, Zhang Q, Qin C, Tian DS
Cellular and molecular neurobiology 2021 Mar;41(2):353-364
Cellular and molecular neurobiology 2021 Mar;41(2):353-364
The antidepressant and anxiolytic effect of GPER on translocator protein (TSPO) via protein kinase a (PKA) signaling in menopausal female rats.
Wang J, Li HY, Shen SY, Zhang JR, Liang LF, Huang HJ, Li B, Wu GC, Zhang YQ, Yu J
The Journal of steroid biochemistry and molecular biology 2021 Mar;207:105807
The Journal of steroid biochemistry and molecular biology 2021 Mar;207:105807
Tea polyphenols inhibit the growth and virulence of ETEC K88.
Ma T, Peng W, Liu Z, Gao T, Liu W, Zhou D, Yang K, Guo R, Duan Z, Liang W, Bei W, Yuan F, Tian Y
Microbial pathogenesis 2021 Mar;152:104640
Microbial pathogenesis 2021 Mar;152:104640
Deletion of the SARS-CoV-2 Spike Cytoplasmic Tail Increases Infectivity in Pseudovirus Neutralization Assays.
Yu J, Li Z, He X, Gebre MS, Bondzie EA, Wan H, Jacob-Dolan C, Martinez DR, Nkolola JP, Baric RS, Barouch DH
Journal of virology 2021 Mar 16;
Journal of virology 2021 Mar 16;
lncRNA PCAT6 facilitates cell proliferation and invasion via regulating the miR-326/hnRNPA2B1 axis in liver cancer.
Luo J, Zheng J, Hao W, Zeng H, Zhang Z, Shao G
Oncology letters 2021 Jun;21(6):471
Oncology letters 2021 Jun;21(6):471
Lipid-injured hepatocytes release sOPN to improve macrophage migration via CD44 engagement and pFak-NFκB signaling.
Jiang X, Zhang F, Ji X, Dong F, Yu H, Xue M, Qiu Y, Yang F, Hu X, Bao Z
Cytokine 2021 Jun;142:155474
Cytokine 2021 Jun;142:155474
Novel Mutations in X-Linked, USP26-Induced Asthenoteratozoospermia and Male Infertility.
Liu C, Shen Y, Shen Q, Zhang W, Wang J, Tang S, Wu H, Tian S, Cong J, He X, Jin L, Zhang F, Jiang X, Cao Y
Cells 2021 Jun 25;10(7)
Cells 2021 Jun 25;10(7)
Restriction of Manganese Intake Prevents the Onset of Brain Manganese Overload in Zip14-/- Mice.
Wu Y, Wei G, Zhao N
International journal of molecular sciences 2021 Jun 24;22(13)
International journal of molecular sciences 2021 Jun 24;22(13)
Centrosomal P4.1-associated protein (CPAP) positively regulates endocytic vesicular transport and lysosome targeting of EGFR.
Gudi R, Palanisamy V, Vasu C
Scientific reports 2021 Jun 16;11(1):12689
Scientific reports 2021 Jun 16;11(1):12689
Knockout analysis of Rab6 effector proteins revealed the role of VPS52 in the secretory pathway.
Homma Y, Fukuda M
Biochemical and biophysical research communications 2021 Jul 5;561:151-157
Biochemical and biophysical research communications 2021 Jul 5;561:151-157
Assessment of the Oral Delivery of a Myelin Basic Protein Gene Promoter with Antiapoptotic bcl-xL (pMBP-bcl-xL) DNA by Cyclic Peptide Nanotubes with Two Aspect Ratios and Its Biodistribution in the Brain and Spinal Cord.
Liaw J, Hsieh WH, Chiou SH, Huang YS, Chang SF
Molecular pharmaceutics 2021 Jul 5;18(7):2556-2573
Molecular pharmaceutics 2021 Jul 5;18(7):2556-2573
A heterozygous hypomorphic mutation of Fanca causes impaired follicle development and subfertility in female mice.
Pan Y, Yang X, Zhang F, Chen S, Zhou Z, Yin H, Ma H, Shang L, Yang J, Li G, Wang Y, Jin L, Shi Q, Wu Y
Molecular genetics and genomics : MGG 2021 Jan;296(1):103-112
Molecular genetics and genomics : MGG 2021 Jan;296(1):103-112
A novel prognostic model based on four circulating miRNA in diffuse large B-cell lymphoma: implications for the roles of MDSC and Th17 cells in lymphoma progression.
Sun R, Zheng Z, Wang L, Cheng S, Shi Q, Qu B, Fu D, Leboeuf C, Zhao Y, Ye J, Janin A, Zhao WL
Molecular oncology 2021 Jan;15(1):246-261
Molecular oncology 2021 Jan;15(1):246-261
Adaptive mutations promote hepatitis C virus assembly by accelerating core translocation to the endoplasmic reticulum.
Zheng F, Li N, Xu Y, Zhou Y, Li YP
The Journal of biological chemistry 2021 Jan-Jun;296:100018
The Journal of biological chemistry 2021 Jan-Jun;296:100018
NT157 Inhibits HCC Migration via Downregulating the STAT3/Jab1 Signaling Pathway.
Yu S, Wang Y, Lv K, Hou J, Li W, Wang X, Guo H, Wang W
Technology in cancer research & treatment 2021 Jan-Dec;20:15330338211027916
Technology in cancer research & treatment 2021 Jan-Dec;20:15330338211027916
Significance of MR/OPN/HMGB1 axis in NAFLD-associated hepatic fibrogenesis.
Tang M, Jia H, Chen S, Yang B, Patpur BK, Song W, Chang Y, Li J, Yang C
Life sciences 2021 Jan 1;264:118619
Life sciences 2021 Jan 1;264:118619
Involvement of GPX4 in irisin's protection against ischemia reperfusion-induced acute kidney injury.
Zhang J, Bi J, Ren Y, Du Z, Li T, Wang T, Zhang L, Wang M, Wei S, Lv Y, Wu R
Journal of cellular physiology 2021 Feb;236(2):931-945
Journal of cellular physiology 2021 Feb;236(2):931-945
Deleterious variants in X-linked CFAP47 induce asthenoteratozoospermia and primary male infertility.
Liu C, Tu C, Wang L, Wu H, Houston BJ, Mastrorosa FK, Zhang W, Shen Y, Wang J, Tian S, Meng L, Cong J, Yang S, Jiang Y, Tang S, Zeng Y, Lv M, Lin G, Li J, Saiyin H, He X, Jin L, Touré A, Ray PF, Veltman JA, Shi Q, O'Bryan MK, Cao Y, Tan YQ, Zhang F
American journal of human genetics 2021 Feb 4;108(2):309-323
American journal of human genetics 2021 Feb 4;108(2):309-323
CircNR3C2 promotes HRD1-mediated tumor-suppressive effect via sponging miR-513a-3p in triple-negative breast cancer.
Fan Y, Wang J, Jin W, Sun Y, Xu Y, Wang Y, Liang X, Su D
Molecular cancer 2021 Feb 2;20(1):25
Molecular cancer 2021 Feb 2;20(1):25
Extending the Calpain-Cathepsin Hypothesis to the Neurovasculature: Protection of Brain Endothelial Cells and Mice from Neurotrauma.
Knopp RC, Jastaniah A, Dubrovskyi O, Gaisina I, Tai L, Thatcher GRJ
ACS pharmacology & translational science 2021 Feb 12;4(1):372-385
ACS pharmacology & translational science 2021 Feb 12;4(1):372-385
Isoliquiritigenin attenuates septic acute kidney injury by regulating ferritinophagy-mediated ferroptosis.
Tang Y, Luo H, Xiao Q, Li L, Zhong X, Zhang J, Wang F, Li G, Wang L, Li Y
Renal failure 2021 Dec;43(1):1551-1560
Renal failure 2021 Dec;43(1):1551-1560
Environmental allergens house dust mite-induced asthma is associated with ferroptosis in the lungs.
Tang W, Dong M, Teng F, Cui J, Zhu X, Wang W, Wuniqiemu T, Qin J, Yi L, Wang S, Dong J, Wei Y
Experimental and therapeutic medicine 2021 Dec;22(6):1483
Experimental and therapeutic medicine 2021 Dec;22(6):1483
Expression pattern of mitogen-activated protein kinase kinase 4 and regulation to antibacterial factor ABF-1/2 in response to bacterial challenge from Artemia parthenogenetica.
Zhang R, Wan K, Liu Y, Wang Z, Zhang D, Yin H
Fish & shellfish immunology 2021 Aug;115:35-42
Fish & shellfish immunology 2021 Aug;115:35-42
Up-regulation of heme oxygenase-1 by celastrol alleviates oxidative stress and vascular calcification in chronic kidney disease.
Yang X, Chen A, Liang Q, Dong Q, Fu M, Liu X, Wang S, Li Y, Ye Y, Lan Z, Ou JS, Lu L, Yan J
Free radical biology & medicine 2021 Aug 20;172:530-540
Free radical biology & medicine 2021 Aug 20;172:530-540
Wu-5, a novel USP10 inhibitor, enhances crenolanib-induced FLT3-ITD-positive AML cell death via inhibiting FLT3 and AMPK pathways.
Yu M, Fang ZX, Wang WW, Zhang Y, Bu ZL, Liu M, Xiao XH, Zhang ZL, Zhang XM, Cao Y, Wang YY, Lei H, Xu HZ, Wu YZ, Liu W, Wu YL
Acta pharmacologica Sinica 2021 Apr;42(4):604-612
Acta pharmacologica Sinica 2021 Apr;42(4):604-612
Haploinsufficiency in non-homologous end joining factor 1 induces ovarian dysfunction in humans and mice.
Li G, Yang X, Wang L, Pan Y, Chen S, Shang L, Zhang Y, Wu Y, Zhou Z, Chen Q, Zhang X, Zhang L, Wang Y, Li J, Jin L, Wu Y, Zhang X, Zhang F
Journal of medical genetics 2021 Apr 22;
Journal of medical genetics 2021 Apr 22;
Loss of CPAP causes sustained EGFR signaling and epithelial-mesenchymal transition in oral cancer.
Gudi RR, Janakiraman H, Howe PH, Palanisamy V, Vasu C
Oncotarget 2021 Apr 13;12(8):807-822
Oncotarget 2021 Apr 13;12(8):807-822
Quercetin Suppresses Apoptosis and Attenuates Intervertebral Disc Degeneration via the SIRT1-Autophagy Pathway.
Wang D, He X, Wang D, Peng P, Xu X, Gao B, Zheng C, Wang H, Jia H, Shang Q, Sun Z, Luo Z, Yang L
Frontiers in cell and developmental biology 2020;8:613006
Frontiers in cell and developmental biology 2020;8:613006
miR-4270 regulates cell proliferation and apoptosis in patients with Sertoli cell-only syndrome by targeting GADD45A and inactivating the NOTCH signaling pathway.
Wang H, Huang Z, Zhao X, Guo B, Ji Z
American journal of translational research 2020;12(9):5730-5740
American journal of translational research 2020;12(9):5730-5740
Overexpression of Platelet-Derived Growth Factor Receptor Α D842V Mutants Prevents Liver Regeneration and Chemically Induced Hepatocarcinogenesis via Inhibition of MET and EGFR.
Du ZQ, Dong J, Li MX, Zhang JF, Bi JB, Ren YF, Zhang LN, Wu RQ, Monga SPS, Lv Y, Zhang XF, Wang HC
Journal of Cancer 2020;11(15):4614-4624
Journal of Cancer 2020;11(15):4614-4624
Cytokine Signature Induced by SARS-CoV-2 Spike Protein in a Mouse Model.
Gu T, Zhao S, Jin G, Song M, Zhi Y, Zhao R, Ma F, Zheng Y, Wang K, Liu H, Xin M, Han W, Li X, Dong CD, Liu K, Dong Z
Frontiers in immunology 2020;11:621441
Frontiers in immunology 2020;11:621441
Mechanism and Molecular Network of RBM8A-Mediated Regulation of Oxaliplatin Resistance in Hepatocellular Carcinoma.
Liang R, Zhang J, Liu Z, Liu Z, Li Q, Luo X, Li Y, Ye J, Lin Y
Frontiers in oncology 2020;10:585452
Frontiers in oncology 2020;10:585452
Fetal liver hepcidin secures iron stores in utero.
Kämmerer L, Mohammad G, Wolna M, Robbins PA, Lakhal-Littleton S
Blood 2020 Sep 24;136(13):1549-1557
Blood 2020 Sep 24;136(13):1549-1557
The common K333Q polymorphism in long-chain acyl-CoA dehydrogenase (LCAD) reduces enzyme stability and function.
Beck ME, Zhang Y, Bharathi SS, Kosmider B, Bahmed K, Dahmer MK, Nogee LM, Goetzman ES
Molecular genetics and metabolism 2020 Sep - Oct;131(1-2):83-89
Molecular genetics and metabolism 2020 Sep - Oct;131(1-2):83-89
Involvement of kindlin-2 in irisin's protection against ischaemia reperfusion-induced liver injury in high-fat diet-fed mice.
Zhang J, Ren Y, Bi J, Wang M, Zhang L, Wang T, Wei S, Mou X, Lv Y, Wu R
Journal of cellular and molecular medicine 2020 Nov;24(22):13081-13092
Journal of cellular and molecular medicine 2020 Nov;24(22):13081-13092
Lithium chloride ameliorated spatial cognitive impairment through activating mTOR phosphorylation and inhibiting excessive autophagy in the repeated cerebral ischemia-reperfusion mouse model.
Xiao Y, Fan M, Jin W, Li WA, Jia Y, Dong Y, Jiang X, Xu J, Meng N, Lv P
Experimental and therapeutic medicine 2020 Nov;20(5):109
Experimental and therapeutic medicine 2020 Nov;20(5):109
Wnt/β-Catenin Signaling Axis Is Required for TFEB-Mediated Gastric Cancer Metastasis and Epithelial-Mesenchymal Transition.
Li S, Liu F, Xu L, Li C, Yang X, Guo B, Gu J, Wang L
Molecular cancer research : MCR 2020 Nov;18(11):1650-1659
Molecular cancer research : MCR 2020 Nov;18(11):1650-1659
Transmembrane protein 106C promotes the development of hepatocellular carcinoma.
Luo X, Han G, Lu R, Guan S, Wang Y, Ju L, Chen L, Shao J, Bian Z
Journal of cellular biochemistry 2020 Nov;121(11):4484-4495
Journal of cellular biochemistry 2020 Nov;121(11):4484-4495
Suppressor of Ty 16 promotes lung cancer malignancy and is negatively regulated by miR-1227-5p.
Yang L, Wang X, Jiao X, Tian B, Zhang M, Zhou C, Wang R, Chen H, Wang B, Li J, Liu J, Zhang G, Liu P
Cancer science 2020 Nov;111(11):4075-4087
Cancer science 2020 Nov;111(11):4075-4087
Hypoxia Alters the Response to Anti-EGFR Therapy by Regulating EGFR Expression and Downstream Signaling in a DNA Methylation-Specific and HIF-Dependent Manner.
Mamo M, Ye IC, DiGiacomo JW, Park JY, Downs B, Gilkes DM
Cancer research 2020 Nov 15;80(22):4998-5010
Cancer research 2020 Nov 15;80(22):4998-5010
Down-regulation of miR-3068-3p enhances kcnip4-regulated A-type potassium current to protect against glutamate-induced excitotoxicity.
Su ZJ, Wang XY, Zhou C, Chai Z
Journal of neurochemistry 2020 Jun;153(5):617-630
Journal of neurochemistry 2020 Jun;153(5):617-630
Combination therapy of BCR-ABL-positive B cell acute lymphoblastic leukemia by tyrosine kinase inhibitor dasatinib and c-JUN N-terminal kinase inhibition.
Xiao X, Liu P, Li D, Xia Z, Wang P, Zhang X, Liu M, Liao L, Jiao B, Ren R
Journal of hematology & oncology 2020 Jun 18;13(1):80
Journal of hematology & oncology 2020 Jun 18;13(1):80
HIGD2A is Required for Assembly of the COX3 Module of Human Mitochondrial Complex IV.
Hock DH, Reljic B, Ang CS, Muellner-Wong L, Mountford HS, Compton AG, Ryan MT, Thorburn DR, Stroud DA
Molecular & cellular proteomics : MCP 2020 Jul;19(7):1145-1160
Molecular & cellular proteomics : MCP 2020 Jul;19(7):1145-1160
Calcium-Inducible MAPK/AP-1 Signaling Drives Semaphorin 3A Expression in Normal Human Epidermal Keratinocytes.
Kamata Y, Tominaga M, Umehara Y, Honda K, Kamo A, Moniaga CS, Komiya E, Toyama S, Suga Y, Ogawa H, Takamori K
The Journal of investigative dermatology 2020 Jul;140(7):1346-1354.e5
The Journal of investigative dermatology 2020 Jul;140(7):1346-1354.e5
The impact of MCM6 on hepatocellular carcinoma in a Southern Chinese Zhuang population.
Jia W, Xie L, Wang X, Zhang Q, Wei B, Li H, Qin S, Chen S, Liu J, Tan Y, Zheng S, Liang X, Yang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110171
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110171
Irisin reverses intestinal epithelial barrier dysfunction during intestinal injury via binding to the integrin αVβ5 receptor.
Bi J, Zhang J, Ren Y, Du Z, Li T, Wang T, Zhang L, Wang M, Wu Z, Lv Y, Wu R
Journal of cellular and molecular medicine 2020 Jan;24(1):996-1009
Journal of cellular and molecular medicine 2020 Jan;24(1):996-1009
TRB3 interacts with ERK and JNK and contributes to the proliferation, apoptosis, and migration of lung adenocarcinoma cells.
Cao X, Fang X, Malik WS, He Y, Li X, Xie M, Sun W, Xu Y, Liu X
Journal of cellular physiology 2020 Jan;235(1):538-547
Journal of cellular physiology 2020 Jan;235(1):538-547
MicroRNA-188 regulates aging-associated metabolic phenotype.
Huang Y, Xiao Y, Liu Y, Guo M, Guo Q, Zhou F, Liu T, Su T, Xiao Y, Luo XH
Aging cell 2020 Jan;19(1):e13077
Aging cell 2020 Jan;19(1):e13077
Osthole delays hepatocarcinogenesis in mice by suppressing AKT/FASN axis and ERK phosphorylation.
Mo Y, Wu Y, Li X, Rao H, Tian X, Wu D, Qiu Z, Zheng G, Hu J
European journal of pharmacology 2020 Jan 15;867:172788
European journal of pharmacology 2020 Jan 15;867:172788
Blockade of JAK2 protects mice against hypoxia-induced pulmonary arterial hypertension by repressing pulmonary arterial smooth muscle cell proliferation.
Zhang L, Wang Y, Wu G, Rao L, Wei Y, Yue H, Yuan T, Yang P, Xiong F, Zhang S, Zhou Q, Chen Z, Li J, Mo BW, Zhang H, Xiong W, Wang CY
Cell proliferation 2020 Feb;53(2):e12742
Cell proliferation 2020 Feb;53(2):e12742
Lipopolysaccharide-Elicited Systemic Inflammation Induces Selective Vulnerability of Cerebral Cortex and Striatum of Developing Glutaryl-CoA Dehydrogenase Deficient (Gcdh-/-) Mice to Oxidative Stress.
Seminotti B, Amaral AU, Grings M, Ribeiro CAJ, Leipnitz G, Wajner M
Neurotoxicity research 2020 Dec;38(4):1024-1036
Neurotoxicity research 2020 Dec;38(4):1024-1036
Diagnostic and prognostic value of MCM3 and its interacting proteins in hepatocellular carcinoma.
Li HT, Wei B, Li ZQ, Wang X, Jia WX, Xu YZ, Liu JY, Shao MN, Chen SX, Mo NF, Zhao D, Zuo WP, Qin J, Li P, Zhang QL, Yang XL
Oncology letters 2020 Dec;20(6):308
Oncology letters 2020 Dec;20(6):308
Targeted Stat2 deletion in conventional dendritic cells impairs CTL responses but does not affect antibody production.
Qiu CC, Kotredes KP, Cremers T, Patel S, Afanassiev A, Slifker M, Gallucci S, Gamero AM
Oncoimmunology 2020 Dec 29;10(1):1860477
Oncoimmunology 2020 Dec 29;10(1):1860477
PTPN2 regulates the activation of KRAS and plays a critical role in proliferation and survival of KRAS-driven cancer cells.
Huang Z, Liu M, Li D, Tan Y, Zhang R, Xia Z, Wang P, Jiao B, Liu P, Ren R
The Journal of biological chemistry 2020 Dec 25;295(52):18343-18354
The Journal of biological chemistry 2020 Dec 25;295(52):18343-18354
Ammonia-Induced Glial-Inflammaging.
Bobermin LD, Roppa RHA, Gonçalves CA, Quincozes-Santos A
Molecular neurobiology 2020 Aug;57(8):3552-3567
Molecular neurobiology 2020 Aug;57(8):3552-3567
Girdin interaction with vimentin induces EMT and promotes the growth and metastasis of pancreatic ductal adenocarcinoma.
Wang W, Chen H, Gao W, Wang S, Wu K, Lu C, Luo X, Li L, Yu C
Oncology reports 2020 Aug;44(2):637-649
Oncology reports 2020 Aug;44(2):637-649
Hydroxysafflor yellow A induces autophagy in human liver cancer cells by regulating Beclin 1 and ERK expression.
Chen Z, Liu L, Liu Y, Wang S, Zhang S, Dong R, Xu M, Ma Y, Wang J, Zhang Q, Wei P
Experimental and therapeutic medicine 2020 Apr;19(4):2989-2996
Experimental and therapeutic medicine 2020 Apr;19(4):2989-2996
Stabilization of PTGES by deubiquitinase USP9X promotes metastatic features of lung cancer via PGE2 signaling.
Wang T, Jing B, Sun B, Liao Y, Song H, Xu D, Guo W, Li K, Hu M, Liu S, Ling J, Kuang Y, Feng Y, Zhou BP, Deng J
American journal of cancer research 2019;9(6):1145-1160
American journal of cancer research 2019;9(6):1145-1160
Dysregulated ENPP1 increases the malignancy of human lung cancer by inducing epithelial-mesenchymal transition phenotypes and stem cell features.
Hu M, Guo W, Liao Y, Xu D, Sun B, Song H, Wang T, Kuang Y, Jing B, Li K, Ling J, Yao F, Deng J
American journal of cancer research 2019;9(1):134-144
American journal of cancer research 2019;9(1):134-144
Comparative Effect of Aqueous and Methanolic Bupleuri Radix Extracts on Hepatic Uptake of High-Density Lipoprotein and Identification of the Potential Target in HFD-Fed Mice.
Tan Z, Huang Y, Chen F, Cao C, Wang S
Evidence-based complementary and alternative medicine : eCAM 2019;2019:9074289
Evidence-based complementary and alternative medicine : eCAM 2019;2019:9074289
Spinal IL-33/ST2 signaling mediates chronic itch in mice through the astrocytic JAK2-STAT3 cascade.
Du L, Hu X, Yang W, Yasheng H, Liu S, Zhang W, Zhou Y, Cui W, Zhu J, Qiao Z, Maoying Q, Chu Y, Zhou H, Wang Y, Mi W
Glia 2019 Sep;67(9):1680-1693
Glia 2019 Sep;67(9):1680-1693
HNF‑4α downregulation promotes tumor migration and invasion by regulating E‑cadherin in renal cell carcinoma.
Gao Y, Yan Y, Guo J, Zhang Q, Bi D, Wang F, Chang Z, Lu L, Yao X, Wei Q
Oncology reports 2019 Sep;42(3):1066-1074
Oncology reports 2019 Sep;42(3):1066-1074
The fatty acid oxidation enzyme long-chain acyl-CoA dehydrogenase can be a source of mitochondrial hydrogen peroxide.
Zhang Y, Bharathi SS, Beck ME, Goetzman ES
Redox biology 2019 Sep;26:101253
Redox biology 2019 Sep;26:101253
Curcumin suppresses osteogenesis by inducing miR-126a-3p and subsequently suppressing the WNT/LRP6 pathway.
Li H, Yue L, Xu H, Li N, Li J, Zhang Z, Zhao RC
Aging 2019 Sep 3;11(17):6983-6998
Aging 2019 Sep 3;11(17):6983-6998
Fate-mapping post-hypoxic tumor cells reveals a ROS-resistant phenotype that promotes metastasis.
Godet I, Shin YJ, Ju JA, Ye IC, Wang G, Gilkes DM
Nature communications 2019 Oct 24;10(1):4862
Nature communications 2019 Oct 24;10(1):4862
SPRY4 is responsible for pathogenesis of adolescent idiopathic scoliosis by contributing to osteogenic differentiation and melatonin response of bone marrow-derived mesenchymal stem cells.
Li J, Li N, Chen Y, Hui S, Fan J, Ye B, Fan Z, Zhang J, Zhao RC, Zhuang Q
Cell death & disease 2019 Oct 23;10(11):805
Cell death & disease 2019 Oct 23;10(11):805
Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease.
Helsley RN, Varadharajan V, Brown AL, Gromovsky AD, Schugar RC, Ramachandiran I, Fung K, Kabbany MN, Banerjee R, Neumann CK, Finney C, Pathak P, Orabi D, Osborn LJ, Massey W, Zhang R, Kadam A, Sansbury BE, Pan C, Sacks J, Lee RG, Crooke RM, Graham MJ, Lemieux ME, Gogonea V, Kirwan JP, Allende DS, Civelek M, Fox PL, Rudel LL, Lusis AJ, Spite M, Brown JM
eLife 2019 Oct 17;8
eLife 2019 Oct 17;8
Vascular Endothelial Growth Factor A Signaling Promotes Spinal Central Sensitization and Pain-related Behaviors in Female Rats with Bone Cancer.
Hu XM, Yang W, Du LX, Cui WQ, Mi WL, Mao-Ying QL, Chu YX, Wang YQ
Anesthesiology 2019 Nov;131(5):1125-1147
Anesthesiology 2019 Nov;131(5):1125-1147
Adaptor protein APPL1 coordinates HDAC3 to modulate brown adipose tissue thermogenesis in mice.
Fan L, Ye H, Wan Y, Qin L, Zhu L, Su J, Zhu X, Zhang L, Miao Q, Zhang Q, Zhang Z, Xu A, Li Y, Li X, Wang Y
Metabolism: clinical and experimental 2019 Nov;100:153955
Metabolism: clinical and experimental 2019 Nov;100:153955
CD1d highly expressed on DCs reduces lung tumor burden by enhancing antitumor immunity.
Li Y, Zhao C, Liu J, Lu Z, Lu M, Gu J, Liu R
Oncology reports 2019 May;41(5):2679-2688
Oncology reports 2019 May;41(5):2679-2688
Downregulated expression of CFHL1 is associated with unfavorable prognosis in postoperative patients with hepatocellular carcinoma.
Feng H, Fang F, Yuan L, Xiao M, Yang XY, Huang Y
Experimental and therapeutic medicine 2019 May;17(5):4073-4079
Experimental and therapeutic medicine 2019 May;17(5):4073-4079
TRPV1 mediates astrocyte activation and interleukin-1β release induced by hypoxic ischemia (HI).
Yang XL, Wang X, Shao L, Jiang GT, Min JW, Mei XY, He XH, Liu WH, Huang WX, Peng BW
Journal of neuroinflammation 2019 May 29;16(1):114
Journal of neuroinflammation 2019 May 29;16(1):114
MiR155 sensitized B-lymphoma cells to anti-PD-L1 antibody via PD-1/PD-L1-mediated lymphoma cell interaction with CD8+T cells.
Zheng Z, Sun R, Zhao HJ, Fu D, Zhong HJ, Weng XQ, Qu B, Zhao Y, Wang L, Zhao WL
Molecular cancer 2019 Mar 30;18(1):54
Molecular cancer 2019 Mar 30;18(1):54
The intestinal metal transporter ZIP14 maintains systemic manganese homeostasis.
Scheiber IF, Wu Y, Morgan SE, Zhao N
The Journal of biological chemistry 2019 Jun 7;294(23):9147-9160
The Journal of biological chemistry 2019 Jun 7;294(23):9147-9160
Manganese Uptake by A549 Cells is Mediated by Both ZIP8 and ZIP14.
Scheiber IF, Alarcon NO, Zhao N
Nutrients 2019 Jun 28;11(7)
Nutrients 2019 Jun 28;11(7)
ITGA6 and RPSA synergistically promote pancreatic cancer invasion and metastasis via PI3K and MAPK signaling pathways.
Wu Y, Tan X, Liu P, Yang Y, Huang Y, Liu X, Meng X, Yu B, Wu M, Jin H
Experimental cell research 2019 Jun 1;379(1):30-47
Experimental cell research 2019 Jun 1;379(1):30-47
The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance.
Huang X, Gan G, Wang X, Xu T, Xie W
Autophagy 2019 Jul;15(7):1258-1279
Autophagy 2019 Jul;15(7):1258-1279
The synergistic effect of NOD2 and TLR4 on the activation of autophagy in human submandibular gland inflammation.
Li J, Li B, Cheng Y, Meng Q, Wei L, Li W, Zhang J, Huang S
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2019 Jan;48(1):87-95
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2019 Jan;48(1):87-95
Anti-MET VHH Pool Overcomes MET-Targeted Cancer Therapeutic Resistance.
Su Z, Han Y, Sun Q, Wang X, Xu T, Xie W, Huang X
Molecular cancer therapeutics 2019 Jan;18(1):100-111
Molecular cancer therapeutics 2019 Jan;18(1):100-111
Triptolide interferes with XRCC1/PARP1-mediated DNA repair and confers sensitization of triple-negative breast cancer cells to cisplatin.
Zhang Z, Sun C, Zhang L, Chi X, Ji J, Gao X, Wang Y, Zhao Z, Liu L, Cao X, Yang Y, Mao W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:1541-1546
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:1541-1546
G-1 exhibit antidepressant effect, increase of hippocampal ERs expression and improve hippocampal redox status in aged female rats.
Wang J, Yu R, Han QQ, Huang HJ, Wang YL, Li HY, Wang HM, Chen XR, Ma SL, Yu J
Behavioural brain research 2019 Feb 1;359:845-852
Behavioural brain research 2019 Feb 1;359:845-852
AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition.
Zhang KL, Shen QQ, Fang YF, Sun YM, Ding J, Chen Y
Acta pharmacologica Sinica 2019 Dec;40(12):1587-1595
Acta pharmacologica Sinica 2019 Dec;40(12):1587-1595
Codelivery of DOX and siRNA by folate-biotin-quaternized starch nanoparticles for promoting synergistic suppression of human lung cancer cells.
Li L, He S, Yu L, Elshazly EH, Wang H, Chen K, Zhang S, Ke L, Gong R
Drug delivery 2019 Dec;26(1):499-508
Drug delivery 2019 Dec;26(1):499-508
miR-942 promotes tumor migration, invasion, and angiogenesis by regulating EMT via BARX2 in non-small-cell lung cancer.
Yang F, Shao C, Wei K, Jing X, Qin Z, Shi Y, Shu Y, Shen H
Journal of cellular physiology 2019 Dec;234(12):23596-23607
Journal of cellular physiology 2019 Dec;234(12):23596-23607
Rare variants in FANCA induce premature ovarian insufficiency.
Yang X, Zhang X, Jiao J, Zhang F, Pan Y, Wang Q, Chen Q, Cai B, Tang S, Zhou Z, Chen S, Yin H, Fu W, Luo Y, Li D, Li G, Shang L, Yang J, Jin L, Shi Q, Wu Y
Human genetics 2019 Dec;138(11-12):1227-1236
Human genetics 2019 Dec;138(11-12):1227-1236
Bi-allelic Mutations in TTC29 Cause Male Subfertility with Asthenoteratospermia in Humans and Mice.
Liu C, He X, Liu W, Yang S, Wang L, Li W, Wu H, Tang S, Ni X, Wang J, Gao Y, Tian S, Zhang L, Cong J, Zhang Z, Tan Q, Zhang J, Li H, Zhong Y, Lv M, Li J, Jin L, Cao Y, Zhang F
American journal of human genetics 2019 Dec 5;105(6):1168-1181
American journal of human genetics 2019 Dec 5;105(6):1168-1181
Shisa3 brakes resistance to EGFR-TKIs in lung adenocarcinoma by suppressing cancer stem cell properties.
Si J, Ma Y, Bi JW, Xiong Y, Lv C, Li S, Wu N, Yang Y
Journal of experimental & clinical cancer research : CR 2019 Dec 4;38(1):481
Journal of experimental & clinical cancer research : CR 2019 Dec 4;38(1):481
FOXP3 pathogenic variants cause male infertility through affecting the proliferation and apoptosis of human spermatogonial stem cells.
Qiu Q, Yu X, Yao C, Hao Y, Fan L, Li C, Xu P, An G, Li Z, He Z
Aging 2019 Dec 19;11(24):12581-12599
Aging 2019 Dec 19;11(24):12581-12599
Palmitoylation is required for TNF-R1 signaling.
Zingler P, Särchen V, Glatter T, Caning L, Saggau C, Kathayat RS, Dickinson BC, Adam D, Schneider-Brachert W, Schütze S, Fritsch J
Cell communication and signaling : CCS 2019 Aug 5;17(1):90
Cell communication and signaling : CCS 2019 Aug 5;17(1):90
KMT2D deficiency enhances the anti-cancer activity of L48H37 in pancreatic ductal adenocarcinoma.
Li SS, Jiang WL, Xiao WQ, Li K, Zhang YF, Guo XY, Dai YQ, Zhao QY, Jiang MJ, Lu ZJ, Wan R
World journal of gastrointestinal oncology 2019 Aug 15;11(8):599-621
World journal of gastrointestinal oncology 2019 Aug 15;11(8):599-621
Adeno-associated virus 2 bound to its cellular receptor AAVR.
Zhang R, Cao L, Cui M, Sun Z, Hu M, Zhang R, Stuart W, Zhao X, Yang Z, Li X, Sun Y, Li S, Ding W, Lou Z, Rao Z
Nature microbiology 2019 Apr;4(4):675-682
Nature microbiology 2019 Apr;4(4):675-682
Downregulation of nucleolar and spindle-associated protein 1 expression suppresses liver cancer cell function.
Wang Y, Ju L, Xiao F, Liu H, Luo X, Chen L, Lu Z, Bian Z
Experimental and therapeutic medicine 2019 Apr;17(4):2969-2978
Experimental and therapeutic medicine 2019 Apr;17(4):2969-2978
The Alisma and Rhizoma decoction abates nonalcoholic steatohepatitis-associated liver injuries in mice by modulating oxidative stress and autophagy.
Xu L, Jing M, Yang L, Jin L, Gong P, Lu J, Lin H, Wang J, Cao Q, Jiang Y
BMC complementary and alternative medicine 2019 Apr 29;19(1):92
BMC complementary and alternative medicine 2019 Apr 29;19(1):92
Iron-dependent CDK1 activity promotes lung carcinogenesis via activation of the GP130/STAT3 signaling pathway.
Kuang Y, Guo W, Ling J, Xu D, Liao Y, Zhao H, Du X, Wang H, Xu M, Song H, Wang T, Jing B, Li K, Hu M, Wu W, Deng J, Wang Q
Cell death & disease 2019 Apr 1;10(4):297
Cell death & disease 2019 Apr 1;10(4):297
Development of an Infectious Cell Culture System for Hepatitis C Virus Genotype 6a Clinical Isolate Using a Novel Strategy and Its Sensitivity to Direct-Acting Antivirals.
Chen M, Zheng F, Yuan G, Duan X, Rong L, Liu J, Feng S, Wang Z, Wang M, Feng Y, Zhou Q, Li J, Deng K, Li C, Xia J, Rao G, Zhou Y, Fu Y, Li YP
Frontiers in microbiology 2018;9:2950
Frontiers in microbiology 2018;9:2950
Chronic restraint stress disturbs meiotic resumption through APC/C-mediated cyclin B1 excessive degradation in mouse oocytes.
Sun J, Guo Y, Zhang Q, Bu S, Li B, Wang Q, Lai D
Cell cycle (Georgetown, Tex.) 2018;17(13):1591-1601
Cell cycle (Georgetown, Tex.) 2018;17(13):1591-1601
Isoliquiritigenin attenuates LPS-induced AKI by suppression of inflammation involving NF-κB pathway.
Tang Y, Wang C, Wang Y, Zhang J, Wang F, Li L, Meng X, Li G, Li Y, Wang L
American journal of translational research 2018;10(12):4141-4151
American journal of translational research 2018;10(12):4141-4151
miR-193a inhibits osteogenic differentiation of bone marrow-derived stroma cell via targeting HMGB1.
Wang SN, Zhao XQ, Yu B, Wang BW
Biochemical and biophysical research communications 2018 Sep 5;503(2):536-543
Biochemical and biophysical research communications 2018 Sep 5;503(2):536-543
Interfilament interaction between IMPDH and CTPS cytoophidia.
Chang CC, Keppeke GD, Sung LY, Liu JL
The FEBS journal 2018 Oct;285(20):3753-3768
The FEBS journal 2018 Oct;285(20):3753-3768
Inhibition of the aryl hydrocarbon receptor/polyamine biosynthesis axis suppresses multiple myeloma.
Bianchi-Smiraglia A, Bagati A, Fink EE, Affronti HC, Lipchick BC, Moparthy S, Long MD, Rosario SR, Lightman SM, Moparthy K, Wolff DW, Yun DH, Han Z, Polechetti A, Roll MV, Gitlin II, Leonova KI, Rowsam AM, Kandel ES, Gudkov AV, Bergsagel PL, Lee KP, Smiraglia DJ, Nikiforov MA
The Journal of clinical investigation 2018 Oct 1;128(10):4682-4696
The Journal of clinical investigation 2018 Oct 1;128(10):4682-4696
Computational and biochemical studies of isothiocyanates as inhibitors of proteasomal cysteine deubiquitinases in human cancer cells.
Ahmed ZSO, Li X, Li F, Cheaito HA, Patel K, Mosallam EM, Elbargeesy GAEH, Dou QP
Journal of cellular biochemistry 2018 Nov;119(11):9006-9016
Journal of cellular biochemistry 2018 Nov;119(11):9006-9016
Natural killer T cell ligand alpha-galactosylceramide protects against gut ischemia reperfusion-induced organ injury in mice.
Zhang J, Bi J, Ren Y, Du Z, Li T, Li Q, Ke M, Dong J, Lv Y, Wu R
Cytokine 2018 Nov;111:237-245
Cytokine 2018 Nov;111:237-245
[6]-Gingerol enhances the radiosensitivity of gastric cancer via G2/M phase arrest and apoptosis induction.
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Oncotarget 2017 Dec 12;8(65):109692-109702
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Western blot analysis of beta actin in various tissues and cell lines using Proteintech antibody HRP-60008 at a dilution of 1:5000.
- Sample type
- tissue
