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- Antibody Data
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- References [5863]
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- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
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- Product number
- 66009-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#66009-1-Ig, RRID:AB_2687938
- Product name
- beta actin antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated Beta Actin antibody (Cat. #66009-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat, hamster, zebrafish, monkey, dog and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat, Canine, Hamster, Simian, Zebrafish
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2D4H5
- Vial size
- 150ul
Submitted references Dehydrocostus lactone suppresses gastric cancer progression by targeting ACLY to inhibit fatty acid synthesis and autophagic flux.
TMEM43 promotes the development of hepatocellular carcinoma by activating VDAC1 through USP7 deubiquitination.
Radix Bupleuri-Radix Paeoniae Alba Inhibits the Development of Hepatocellular Carcinoma through Activation of the PTEN/PD-L1 Axis within the Immune Microenvironment.
Inhibition of IGF2BP1 attenuates the progression of endometriosis through PTBP1.
Hsa_circ_0008833 promotes COPD progression via inducing pyroptosis in bronchial epithelial cells.
POMC Neuron BBSome Regulation of Body Weight is Independent of its Ciliary Function.
ABCF1/CXCL12/CXCR4 Enhances Glioblastoma Cell Proliferation, Migration, and Invasion by Activating the PI3K/AKT Signal Pathway.
Therapeutic potential of HUC-MSC-exos primed with IFN-γ against LPS-induced acute lung injury.
Apigenin targets fetuin-A to ameliorate obesity-induced insulin resistance.
HNF4A-Bridging the Gap Between Intestinal Metaplasia and Gastric Cancer.
Trilobatin ameliorates dextran sulfate sodium-induced ulcerative colitis in mice via the NF-κB pathway and alterations in gut microbiota.
Echinatin attenuates acute lung injury and inflammatory responses via TAK1-MAPK/NF-κB and Keap1-Nrf2-HO-1 signaling pathways in macrophages.
Comprehensive analysis and validation reveal DEPDC1 as a potential diagnostic biomarker associated with tumor immunity in non-small-cell lung cancer.
A comparative study of apoptosis, pyroptosis, necroptosis, and PANoptosis components in mouse and human cells.
Mesencephalic Astrocyte-derived Neurotrophic Factor Supports Hepatitis B Virus-induced Immunotolerance.
Xinfeng Capsule Inhibits Pyroptosis and Ameliorates Myocardial Injury in Rats with Adjuvant Arthritis via the GAS5/miR-21/TLR4 Axis.
Propofol and Dexmedetomidine Ameliorate Endotoxemia-Associated Encephalopathy via Inhibiting Ferroptosis.
DNMT3B Alleviates Liver Steatosis Induced by Chronic Low-grade LPS via Inhibiting CIDEA Expression.
Downregulation of ST6GAL2 Correlates to Liver Inflammation and Predicts Adverse Prognosis in Hepatocellular Carcinoma.
Tat-CIRP Peptide Facilitates Frozen Wound Healing by Ameliorating Inflammation and Promoting Angiogenesis.
Maresin-1 Attenuates Sepsis-Associated Acute Kidney Injury via Suppressing Inflammation, Endoplasmic Reticulum Stress and Pyroptosis by Activating the AMPK/SIRT3 Pathway.
MAT2A inhibition suppresses inflammation in Porphyromonas gingivalis-infected human gingival fibroblasts.
MiR-15b-3p weakens bicalutamide sensitivity in prostate cancer via targeting KLF2 to suppress ferroptosis.
Cuproptosis-related genes score and its hub gene GCSH: A novel predictor for cholangiocarcinomas prognosis based on RNA seq and experimental analyses.
AQP3 Promotes the Invasion and Metastasis in Cervical Cancer by Regulating NOX4-derived H(2)O(2) Activation of Syk/PI3K/Akt Signaling Axis.
CENPW knockdown inhibits progression of bladder cancer through inducing cell cycle arrest and apoptosis.
Exploring the biological behavior and underlying mechanism of KITLG in triple-negative breast cancer.
Radiosensitization of Osteosarcoma Cells Using the PARP Inhibitor Olaparib Combined with X-rays or Carbon Ions.
Expression and clinical significance of ECHS1 in gastric cancer.
Involvement of autophagy in mesaconitine-induced neurotoxicity in HT22 cells revealed through integrated transcriptomic, proteomic, and m6A epitranscriptomic profiling.
TAK1 inhibition mitigates intracerebral hemorrhage-induced brain injury through reduction of oxidative stress and neuronal pyroptosis via the NRF2 signaling pathway.
PCBP1 interacts with the HTLV-1 Tax oncoprotein to potentiate NF-κB activation.
Novel prognostic biomarker TBC1D1 is associated with immunotherapy resistance in gliomas.
Identification of claudin-2 as a promising biomarker for early diagnosis of pre-diabetes.
A hypoxia-related genes prognostic risk model, and mechanisms of hypoxia contributing to poor prognosis through immune microenvironment and drug resistance in acute myeloid leukemia.
Genistein is effective in inhibiting Orf virus infection in vitro by targeting viral RNA polymerase subunit RPO30 protein.
TRIM56: a promising prognostic immune biomarker for glioma revealed by pan-cancer and single-cell analysis.
Single-cell RNA sequencing reveals S100a9(hi) macrophages promote the transition from acute inflammation to fibrotic remodeling after myocardial ischemia‒reperfusion.
Ginsenoside Rg3 decreases breast cancer stem-like phenotypes through impairing MYC mRNA stability.
Polydatin ameliorates low-density lipoprotein cholesterol and lipid metabolism by downregulating proprotein convertase subtilisin/kexin type 9 (PCSK9) in triple-negative breast cancer with hyperlipidemia.
Bioinformatics analysis and experimental verification of TIGD1 in non-small cell lung cancer.
IGF2BP2 modulates autophagy and serves as a prognostic marker in glioma.
Exosomes Derived from Meningitic Escherichia coli-Infected Brain Microvascular Endothelial Cells Facilitate Astrocyte Activation.
Restoration of HMGCS2-mediated ketogenesis alleviates tacrolimus-induced hepatic lipid metabolism disorder.
mtDNA amplifies beryllium sulfate-induced inflammatory responses via the cGAS-STING pathway in 16HBE cells.
NOX1 triggers ferroptosis and ferritinophagy, contributes to Parkinson's disease.
Zinc-Mediated Endoplasmic Reticulum Stress and Metallothionein Alleviate Arsenic-Induced Cardiotoxicity in Cyprinus Carpio.
PRM1201 effectively inhibits colorectal cancer metastasis via shaping gut microbiota and short- chain fatty acids.
Notch-Targeted Therapeutic in Colorectal Cancer by Notch1 Attenuation Via Tumor Microenvironment-Responsive Cascade DNA Delivery.
Knockdown of programmed cell death factor 4 restores erectile function by attenuating apoptosis in rats with bilateral cavernous nerve crush injury.
A novel UVA-associated circUBE2I mediates ferroptosis in HaCaT cells.
Metabolomics reveals the implication of acetoacetate and ketogenic diet therapy in radioiodine-refractory differentiated thyroid carcinoma.
Reduced levels of MRE11 cause disease phenotypes distinct from ataxia telangiectasia-like disorder.
Tanreqing injection inhibits influenza virus replication by promoting the fusion of autophagosomes with lysosomes: An integrated pharmacological study.
Harmine inhibits pulmonary fibrosis through regulating DNA damage repair-related genes and activation of TP53-Gadd45α pathway.
Berberine as a potential enhancer for 5-ALA-mediated fluorescence in glioblastoma: increasing detectability of infiltrating glioma stem cells to optimize 5-ALA-guided surgery.
Central role of Sigma-1 receptor in ochratoxin A-induced ferroptosis.
AQP4 Endocytosis-Lysosome Degradation Mediated by MMP-9/β-DG Involved in Diabetes Cognitive Impairment.
Influenza A Virus PB1-F2 Induces Affective Disorder by Interfering Synaptic Plasticity in Hippocampal Dentate Gyrus.
Dexmedetomidine attenuates ferroptosis by Keap1-Nrf2/HO-1 pathway in LPS-induced acute kidney injury.
PTPN7 mediates macrophage-polarization and determines immunotherapy in gliomas: A single-cell sequencing analysis.
Circular RNA CircACAP2 regulates temporomandibular joint osteoarthritis via miR-21-5p/PLAG1 axis.
Panobinostat sensitizes AraC-resistant AML cells to the combination of azacitidine and venetoclax.
Ginkgo Biloba Extract Can Antagonize Subchronic Arsenite Exposure-Induced Hepatocyte Senescence by Inhibiting Oxidative Damage and Inflammation in Rats.
Capturing acyl-enzyme intermediates with genetically encoded 2,3-diaminopropionic acid for hydrolase substrate identification.
LncRNA H19/miR-107 regulates endothelial progenitor cell pyroptosis and promotes flow recovery of lower extremity ischemia through targeting FADD.
Identification of TACSTD2 as novel therapeutic targets for cisplatin-induced acute kidney injury by multi-omics data integration.
Neutrophil-Mediated Nanozyme Delivery System for Acute Kidney Injury Therapy.
Untargeted serum and gastric metabolomics and network pharmacology analysis reveal the superior efficacy of zingiberis rhizoma recens-/euodiae fructus-processed Coptidis Rhizoma on gastric ulcer rats.
Emerging perfluoroalkyl substances retard skeletal growth by accelerating osteoblasts senescence via ferroptosis.
p38 MAPK inhibitor SB202190 suppresses ferroptosis in the glutamate-induced retinal excitotoxicity glaucoma model.
Engineered extracellular vesicles enable high-efficient delivery of intracellular therapeutic proteins.
Metformin attenuates PM(2.5)-induced oxidative stress by inhibiting the AhR/CYP1A1 pathway in proximal renal tubular epithelial cells.
Activation of autophagy by Citri Reticulatae Semen extract ameliorates amyloid-beta-induced cell death and cognition deficits in Alzheimer's disease.
Gas6/AXL Alleviates Hepatic Ischemia/Reperfusion Injury by Inhibiting Ferroptosis via the PI3K/AKT Pathway.
Autophagy-related protein 5 (ATG5) interacts with bone marrow stromal cell antigen 2 (BST2) to stimulate HBV replication through antagonizing the antiviral activity of BST2.
The association between endothelial function and autoimmune thyroiditis induced by iodine excess.
Excessive linoleic acid induces muscle oxidative stress through 5-lipoxygenase-dependent peroxidation.
Berberine inhibits excessive autophagy and protects myocardium against ischemia/reperfusion injury via the RhoE/AMPK pathway.
Butyrate increases methylglyoxal production through regulation of the JAK2/Stat3/Nrf2/Glo1 pathway in castration‑resistant prostate cancer cells.
Targeting Large-Conductance Calcium-Activated Potassium Channels to Ameliorate Lipopolysaccharide-Induced Depressive-Like Behavior in Mice.
Macrophages promote the transition from myocardial ischemia reperfusion injury to cardiac fibrosis in mice through GMCSF/CCL2/CCR2 and phenotype switching.
Mangiferin alleviates diabetic pulmonary fibrosis in mice via inhibiting endothelial-mesenchymal transition through AMPK/FoxO3/SIRT3 axis.
Characteristics of spatial protein expression in the mouse cochlear sensory epithelia: Implications for age-related hearing loss.
Colorectal cancer cells secreting DKK4 transform fibroblasts to promote tumour metastasis.
Molecular mechanism of quercetin in treating RA-ILD based on network pharmacology, molecular docking, and experimental validation.
TOPK promotes the development of psoriasis and worenine alleviates psoriasiform dermatitis by inhibiting TOPK activity.
4-PBA exerts brain-protective effects against sepsis-associated encephalopathy in a mouse model of sepsis.
TSG6-Exo@CS/GP Attenuates Endometrium Fibrosis by Inhibiting Macrophage Activation in a Murine IUA Model.
SPI1 activates TGF-β1/PI3K/Akt signaling through transcriptional upregulation of FKBP12 to support the mesenchymal phenotype of glioma stem cells.
Human umbilical cord mesenchymal stem cell-derived exosomal miR-214-3p regulates the progression of gallbladder cancer by regulating ACLY/GLUT1.
Retinoblastoma-associated protein is important for TRIM24-mediated activation of the mTOR signaling pathway through DUSP2 action in prostate cancer.
Electroacupuncture regulates Rab5a-mediating NGF transduction to improve learning and memory ability in the early stage of AD mice.
Bovine parainfluenza virus type 3 infections induce ER stress-mediated autophagy to facilitate virus replication.
Epigenetic regulation by KDM5A mediates the effects of prenatal PM(2.5) exposure on hippocampal development and synaptic integrity through the Shh signaling pathway.
Icariin‑curcumol promotes ferroptosis in prostate cancer cells through Nrf2/HO‑1 signaling.
SUMOylation of GMFB regulates its stability and function in retinal pigment epithelial cells under hyperglycemia.
Iridoid glycosides from Morinda officinalis induce lysosomal biogenesis and promote autophagic flux to attenuate oxidative stress.
Circular RNA hsa_circ_0094976 modulates GPR155 to inhibit gastric adenocarcinoma malignant characteristics by targeting miR-223-3p.
TGF-β1 inhibitor P144 protects against benign restenosis after esophageal stenting through TGF-β1/Smads signaling pathway inhibition.
Chemical proteomics reveals the target landscape of 1,000 kinase inhibitors.
TRIM22 facilitates autophagosome-lysosome fusion by mediating the association of GABARAPs and PLEKHM1.
Endorepellin downregulation promotes angiogenesis after experimental traumatic brain injury.
Toosendanin induces hepatotoxicity via disrupting LXRα/Lipin1/SREBP1 mediated lipid metabolism.
Human epididymis protein 4, a novel potential biomarker for diagnostic and prognosis monitoring of lung cancer.
Novel small molecule DMAMCL induces differentiation in rhabdomyosarcoma by downregulating of DLL1.
Protective effect of esculentoside A against myocardial infarction via targeting C-X-C motif chemokine receptor 2.
Upregulation of ATF4 mediates the cellular adaptation to pharmacologic inhibition of amino acid transporter LAT1 in pancreatic ductal adenocarcinoma cells.
Discovery of a novel small-molecule activator of SIRT3 that inhibits cell proliferation and migration by apoptosis and autophagy-dependent cell death pathways in colorectal cancer.
Riboflavin protects against pancreatic cancer metastasis by targeting TGF-β receptor 1.
WTAP-Mediated N6-Methyladenosine of RNAs Facilitate the Pathophysiology of Atopic Dermatitis.
Urolithin A Hijacks ERK1/2-ULK1 Cascade to Improve CD8(+) T Cell Fitness for Antitumor Immunity.
COSA-1 mediated pro-crossover complex formation promotes meiotic crossing over in C. elegans.
Iron (II)-based metal-organic framework nanozyme for boosting tumor ferroptosis through inhibiting DNA damage repair and system Xc().
Aging-induced tRNA(Glu)-derived fragment impairs glutamate biosynthesis by targeting mitochondrial translation-dependent cristae organization.
Metaplastic regeneration in the mouse stomach requires a reactive oxygen species pathway.
Isocitrate dehydrogenase 1 upregulation in urinary extracellular vesicles from proximal tubules of type 2 diabetic rats.
Melatonin suppresses atherosclerosis by ferroptosis inhibition via activating NRF2 pathway.
Senegenin Attenuates Pulmonary Fibrosis by Inhibiting Oxidative-Stress-Induced Epithelial Cell Senescence through Activation of the Sirt1/Pgc-1α Signaling Pathway.
Serum sSelectin-L is an early specific indicator of radiation injury.
Inhibitory effects of black phosphorus nanosheets on tumor cell proliferation through downregulation of ADIPOQ and downstream signaling pathways.
Phosphatidylserine Counteracts the High Stocking Density-Induced Stress Response, Redox Imbalance and Immunosuppression in Fish Megalobrama ambylsephala.
Integrated network pharmacology and experimental validation-based approach to reveal the underlying mechanisms and key material basis of Jinhua Qinggan granules against acute lung injury.
Gancao decoction attenuates hepatic necroptosis via activating caspase 8 in cholestatic liver injury.
APC/C-regulated CPT1C promotes tumor progression by upregulating the energy supply and accelerating the G1/S transition.
Reduction of specific enterocytes from loss of intestinal LGR4 improves lipid metabolism in mice.
Pacidusin B isolated from Phyllanthus acidus triggers ferroptotic cell death in HT1080 cells.
TRIM65 promotes renal cell carcinoma through ubiquitination and degradation of BTG3.
Combination treatment with ferroptosis and autophagy inducers significantly inhibit the proliferation and migration of oral squamous cell carcinoma.
Silent information regulator 2 deficiency exacerbates chronic cold exposure-induced colonic injury and p65 activation in mice.
Serine/Arginine-Rich Splicing Factor 7 Knockdown Inhibits Aerobic Glycolysis and Growth in HepG2 Cells by Regulating PKM2 Expression.
BAP31 Plays an Essential Role in Mouse B Cell Development via Regulation of BCR Signaling.
Porphyromonas gingivalis OMVs promoting endothelial dysfunction via the STING pathway in periodontitis.
KAT6A deficiency impairs cognitive functions through suppressing RSPO2/Wnt signaling in hippocampal CA3.
FOXC1 regulates endothelial CD98 (LAT1/4F2hc) expression in retinal angiogenesis and blood-retina barrier formation.
The miR-641-STIM1 and SATB1 axes play important roles in the regulation of the Th17/Treg balance in ITP.
Alleviative effects of the parthenolide derivative ACT001 on insulin resistance induced by sodium propionate combined with a high-fat diet and its potential mechanisms.
Pyroptosis inhibitors MCC950 and VX-765 mitigate myocardial injury by alleviating oxidative stress, inflammation, and apoptosis in acute myocardial hypoxia.
Caspase-3/Gasdermin E-mediated pyroptosis contributes to Ricin toxin-induced inflammation.
Wine- and stir-frying processing of Cuscutae Semen enhance its ability to alleviate oxidative stress and apoptosis via the Keap 1-Nrf2/HO-1 and PI3K/AKT pathways in H(2)O(2)-challenged KGN human granulosa cell line.
iTRAQ-based proteomic study on monocyte cell model discovered an association of LAMP2 downregulation with HIV-1 latency.
Mecp2 fine-tunes quiescence exit by targeting nuclear receptors.
Dihydroquercetin regulates HIF-1α/AKT/NR2B signalling to improve impaired brain function in rats with metabolic syndrome.
Pseudorabies virus usurps non-muscle myosin heavy chain IIA to dampen viral DNA recognition by cGAS for antagonism of host antiviral innate immunity.
METTL3 Promotes OSCC Progression by Down-Regulating WEE1 in a m6A-YTHDF2-Dependent Manner.
Epigenetic silencing of LDHB promotes hepatocellular carcinoma by remodeling the tumor microenvironment.
The crosstalk between macrophages and cancer cells potentiates pancreatic cancer cachexia.
Iron promotes ovarian cancer malignancy and advances platinum resistance by enhancing DNA repair via FTH1/FTL/POLQ/RAD51 axis.
MSC-derived exosomal miR-140-3p improves cognitive dysfunction in sepsis-associated encephalopathy by HMGB1 and S-lactoylglutathione metabolism.
Cepharanthine synergistically promotes methylprednisolone pharmacodynamics against human peripheral blood mononuclear cells possibly via regulation of P-glycoprotein/glucocorticoid receptor translocation.
Glycosides of Buyang Huanwu decoction inhibits inflammation associated with cerebral ischemia-reperfusion via the PINK1/Parkin mitophagy pathway.
Helicobacter pylori disrupts gastric mucosal homeostasis by stimulating macrophages to secrete CCL3.
Targeting BRD4 with PROTAC degrader ameliorates LPS-induced acute lung injury by inhibiting M1 alveolar macrophage polarization.
The E3 ubiquitin ligase TRIM9 regulates synaptic function and actin dynamics in response to netrin-1.
The role of the sensory input intervention in recovery of the motor function in hypoxic ischemic encephalopathy rat model.
Lrg1 silencing attenuates ischemia-reperfusion renal injury by regulating autophagy and apoptosis through the TGFβ1- Smad1/5 signaling pathway.
Myelin repair of spinal cord injury in adult mice induced by treadmill training upregulated peroxisome proliferator-activated receptor gamma coactivator 1 alpha.
Knockdown of SIK3 in the CA1 Region can Reduce Seizure Susceptibility in Mice by Inhibiting Decreases in GABA(A)R α1 Expression.
Involvement of DJ-1 in the pathogenesis of intervertebral disc degeneration via hexokinase 2-mediated mitophagy.
Gene expression analysis of oxidative stress-related genes in the apical, middle, and basal turns of the cochlea.
Morphine induces HADHA succinylation, while HADHA desuccinylation alleviates morphine tolerance by influencing autophagy.
Lead inhibits microglial cell migration via suppression of store-operated calcium entry.
Melatonin ameliorates PM2.5-induced spermatogenesis disorder by preserving H3K9 methylation and SIRT3.
Hypothermic machine perfusion reduces donation after circulatory death liver ischemia-reperfusion injury through the SERPINA3-mediated PI3Kδ/Akt pathway.
Rab5c promotes RSV and ADV replication by autophagy in respiratory epithelial cells.
40 Hz light flickering promotes sleep through cortical adenosine signaling.
Fucoidan suppresses proliferation and epithelial-mesenchymal transition process via Wnt/β-catenin signalling in hemangioma.
Divergent Roles of KLF4 During Primordial Germ Cell Fate Induction from Human Embryonic Stem Cells.
Lipid overload-induced RTN3 activation leads to cardiac dysfunction by promoting lipid droplet biogenesis.
Normobaric hyperoxia alleviates complement C3-mediated synaptic pruning and brain injury after intracerebral hemorrhage.
Rasd1 is involved in white matter injury through neuron-oligodendrocyte communication after subarachnoid hemorrhage.
Inhibition of HDAC6 promotes microvascular endothelial cells to phagocytize myelin debris and reduces inflammatory response to accelerate the repair of spinal cord injury.
CD8(+) T cell infiltration and proliferation in the brainstem during experimental cerebral malaria.
Selective HDAC6 inhibition protects against blood-brain barrier dysfunction after intracerebral hemorrhage.
Protective Effects of Danmu Extract Syrup on Acute Lung Injury Induced by Lipopolysaccharide in Mice through Endothelial Barrier Repair.
Capnocytophaga gingivalis is a potential tumor promotor in oral cancer.
Blockade of BTLA alone or in combination with PD-1 restores the activation and proliferation of CD8(+) T cells during in vitro infection with NCP BVDV.
African swine fever virus maintains de novo global cellular protein synthesis and inhibits stress granules formation via dephosphorylating eIF2α.
A lncRNA Dleu2-encoded peptide relieves autoimmunity by facilitating Smad3-mediated Treg induction.
Alpha-Emitter Radium-223 Induces STING-Dependent Pyroptosis to Trigger Robust Antitumor Immunity.
A genome-wide CRISPR screening uncovers that TOB1 acts as a key host factor for FMDV infection via both IFN and EGFR mediated pathways.
A preliminary mechanistic exploration of the effect of leptin on the docetaxel sensitivity of MDA‑MB‑231 triple‑negative breast cancer cells.
STING activation in cardiomyocytes drives hypertrophy-associated heart failure via NF-κB-mediated inflammatory response.
Ramelteon alleviates myocardial ischemia/reperfusion injury (MIRI) through Sirt3--dependent regulation of cardiomyocyte apoptosis.
Proteomic Characterization Identifies Clinically Relevant Subgroups of Gastrointestinal Stromal Tumors.
Inhibition of amino acid transporter LAT1 in cancer cells suppresses G0/G1-S transition by downregulating cyclin D1 via p38 MAPK activation.
TOX3 deficiency mitigates hyperglycemia by suppressing hepatic gluconeogenesis through FoxO1.
Mucous cell histopathology and label-free quantitative proteomic analysis of skin mucus in fat greenling (Hexagrammos otakii) infected with Vibrio harveyi.
Design, synthesis, and pharmacological evaluation of novel benzothiazole derivatives targeting LCK in acute lymphoblastic leukemia.
Novel compound heterozygous variants in FANCI cause premature ovarian insufficiency.
Tau induces inflammasome activation and microgliosis through acetylating NLRP3.
Hepatic transcriptome discloses the potential targets of Xuefu Zhuyu Decoction ameliorating non-alcoholic fatty liver disease induced by high-fat diet.
MBIP promotes ESCC metastasis by activating MAPK pathway.
Identification of PRDX5 as A Target for The Treatment of Castration-Resistant Prostate Cancer.
Cfp1 Controls Cardiomyocyte Maturation by Modifying Histone H3K4me3 of Structural, Metabolic, and Contractile Related Genes.
Disrupting PIAS3-mediated SUMOylation of MLK3 ameliorates poststroke neuronal damage and deficits in cognitive and sensorimotor behaviors.
Polyphyllin B inhibited STAT3/NCOA4 pathway and restored gut microbiota to ameliorate lung tissue injury in cigarette smoke-induced mice.
Aryl hydrocarbon receptor suppresses STING-mediated type I IFN expression in triple-negative breast cancer.
High expression of KIFC1 is a poor prognostic biomarker and correlates with TP53 mutation in lung cancer.
Interleukin-22 Contributes to Blood-Brain Barrier Disruption via STAT3/VEGFA Activation in Escherichia coli Meningitis.
Late-stage modification of complex drug: Base-controlled Pd-catalyzed regioselective synthesis and bioactivity of arylated osimertinibs.
Identified S100A9 as a target for diagnosis and treatment of ulcerative colitis by bioinformatics analysis.
Hinokitiol protects gastric injury from ethanol exposure via its iron sequestration capacity.
Dietary Restriction Improves Perioperative Neurocognitive Disorders by Inhibiting Neuroinflammation and Gut Microbial Dysbiosis.
T-2 toxin induces mitochondrial dysfunction in chondrocytes via the p53-cyclophilin D pathway.
Augmentation of scleral glycolysis promotes myopia through histone lactylation.
Whole genome sequencing analysis of Limosilactobacillus reuteri from the intestinal tract of mice recovering from ulcerative colitis and preliminary study on anti-inflammatory effects of its derived peptides.
SARS-CoV-2 NSP2 as a Potential Delivery Vehicle for Proteins.
CSNK2A1 confers gemcitabine resistance to pancreatic ductal adenocarcinoma via inducing autophagy.
WNT2B activates macrophages via NF-κB signaling pathway in inflammatory bowel disease.
PGRN inhibits CD8(+)T cell recruitment and promotes breast cancer progression by up-regulating ICAM-1 on TAM.
Pcgf5: An important regulatory factor in early embryonic neural induction.
Elucidating the role of intrinsic adenosine A1 receptors in acute alcoholism using human-induced pluripotent stem cell-derived hepatocytes.
Fisetin Alleviates Inflammation and Oxidative Stress in Deep Vein Thrombosis via MAPK and NRF2 Signaling Pathway.
The Tumor Microenvironment Mediates the HIF-1α/PD-L1 Pathway to Promote Immune Escape in Colorectal Cancer.
Human periodontal ligament stem cell sheets activated by graphene oxide quantum dots repair periodontal bone defects by promoting mitochondrial dynamics dependent osteogenic differentiation.
SRRM2 phase separation drives assembly of nuclear speckle subcompartments.
Exploring the molecular mechanism of Artemisia rupestris L. for the treatment of hepatocellular carcinoma via PI3K/AKT pathway.
MiR-155-5p improves the insulin sensitivity of trophoblasts by targeting CEBPB in gestational diabetes mellitus.
Hypoxia-Challenged Pancreatic Adenocarcinoma Cell-Derived Exosomal circR3HCC1L Drives Tumor Growth Via Upregulating PKM2 Through Sequestering miR-873-5p.
A novel microglia-targeting strategy based on nanoparticle-mediated delivery of miR-26a-5p for long-lasting analgesia in chronic pain.
AURKA emerges as a vulnerable target for KEAP1-deficient non-small cell lung cancer by activation of asparagine synthesis.
Identification and validation of DHCR7 as a diagnostic biomarker involved in the proliferation and mitochondrial function of breast cancer.
G-quadruplexes on chromosomal DNA negatively regulates topoisomerase 1 activity.
Trimethylamine N-oxide impairs β-cell function and glucose tolerance.
[Activation of α7 nAChR improves white fat homeostasis and promotes beige adipogenesis and thermogenesis in obese mice].
Bi(2)S(3)/Ti(3)C(2)-TPP nano-heterostructures induced by near-infrared for photodynamic therapy combined with photothermal therapy on hypoxic tumors.
Identification and validation of a novel signature based on macrophage marker genes for predicting prognosis and drug response in kidney renal clear cell carcinoma by integrated analysis of single cell and bulk RNA sequencing.
Extracellular vesicles secreted from mesenchymal stem cells ameliorate renal ischemia reperfusion injury by delivering miR-100-5p targeting FKBP5/AKT axis.
Lactobacillus rhamnosus GG ameliorates hyperuricemia in a novel model.
Endogenous TDP-43 mislocalization in a novel knock-in mouse model reveals DNA repair impairment, inflammation, and neuronal senescence.
Ubiquitin-specific proteinase 1 stabilizes PRRSV nonstructural protein Nsp1β to promote viral replication by regulating K48 ubiquitination.
RBM14 inhibits the replication of porcine epidemic diarrhea virus by recruiting p62 to degrade nucleocapsid protein through the activation of autophagy and interferon pathway.
Deacetylase Sirtuin 1 mitigates type I IFN- and type II IFN-induced signaling and antiviral immunity.
ART1 knockdown decreases the IL-6-induced proliferation of colorectal cancer cells.
Pan-cancer analysis of NUP155 and validation of its role in breast cancer cell proliferation, migration, and apoptosis.
CircALMS1 Alleviates Pulmonary Microvascular Endothelial Cell Dysfunction in Pulmonary Hypertension.
Loss of Preproinsulin Interaction with Signal Recognition Particle Activates Protein Quality Control, Decreasing mRNA Stability.
Co-exposure to polystyrene nanoplastics and triclosan induces synergistic cytotoxicity in human KGN granulosa cells by promoting reactive oxygen species accumulation.
TET2 stabilized by deubiquitinase USP21 ameliorates cigarette smoke-induced apoptosis in airway epithelial cells.
Dietary protein restriction regulates skeletal muscle fiber metabolic characteristics associated with the FGF21-ERK1/2 pathway.
Independent prognostic value of CLDN6 in bladder cancer based on M2 macrophages related signature.
The mechanisms and therapeutic potential of clopidogrel in mitigating diabetic cardiomyopathy in db/db mice.
FTO attenuates the cytotoxicity of cisplatin in KGN granulosa cell-like tumour cells by regulating the Hippo/YAP1 signalling pathway.
l-Theanine delays d-galactose-induced senescence by regulating the cell cycle and inhibiting apoptosis in rat intestinal cells.
L-Theanine alleviates heat stress through modulation of gut microbiota and immunity.
GPR39 Agonist TC-G 1008 Promoted Mitochondrial Biogenesis and Improved Antioxidative Capability via CREB/PGC-1α Pathway Following Intracerebral Hemorrhage in Mice.
Purinergic P2X7 receptor involves in anti-retinal photodamage effects of berberine.
SARS-CoV-2 remodels the Golgi apparatus to facilitate viral assembly and secretion.
MCL1 inhibition: a promising approach to augment the efficacy of sorafenib in NSCLC through ferroptosis induction.
HLA-class II restricted TCR targeting human papillomavirus type 18 E7 induces solid tumor remission in mice.
BNC1 deficiency induces mitochondrial dysfunction-triggered spermatogonia apoptosis through the CREB/SIRT1/FOXO3 pathway: the therapeutic potential of nicotinamide riboside and metformin†.
Sulforaphane Regulates Macrophage M1/M2 Polarization to Attenuate Macrophage-induced Caco-2 Cell Injury in an Inflammatory Environment.
Cluster of Differentiation-44-Targeting Prussian Blue Nanoparticles Onloaded with Colchicine for Atherosclerotic Plaque Regression in a Mice Model.
Synergistic effects and molecular mechanisms of DL-3-n-butylphthalide combined with dual antiplatelet therapy in acute ischemic stroke.
High-frequency repetitive transcranial magnetic stimulation improves depressive-like behaviors in CUMS-induced rats by modulating astrocyte GLT-1 to reduce glutamate toxicity.
Testosterone regulates thymic remodeling by altering metabolic reprogramming in male rats.
From inflammation to pyroptosis: Understanding the consequences of cadmium exposure in chicken liver cells.
Comprehensive Atlas of Alternative Splicing Reveals NSRP1 Promoting Adipogenesis through CCDC18.
P2Y(13) receptor involved in HIV-1 gp120 induced neuropathy in superior cervical ganglia through NLRP3 inflammasome activation.
Down-regulating nuclear factor of activated T cells 1 alleviates cognitive deficits in a mouse model of sepsis-associated encephalopathy, possibly by stimulating hippocampal neurogenesis.
Decreased NSD2 impairs stromal cell proliferation in human endometrium via reprogramming H3K36me2.
Depletion of the N(6)-Methyladenosine (m6A) reader protein IGF2BP3 induces ferroptosis in glioma by modulating the expression of GPX4.
VD(3)/VDR attenuates bisphenol A-induced impairment in mouse Leydig cells via regulation of autophagy.
Knocking Down PIAS3 Reduces H(2)O(2)-induced Oxidative Stress Injury in HT22 Cells.
Transcriptomic analysis reveals molecular characterization and immune landscape of PANoptosis-related genes in atherosclerosis.
Jiaohong pills attenuate neuroinflammation and amyloid-β protein-induced cognitive deficits by modulating the mitogen-activated protein kinase/nuclear factor kappa-B pathway.
GSK-126 Attenuates Cell Apoptosis in Ischemic Brain Injury by Modulating the EZH2-H3K27me3-Bcl2l1 Axis.
HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression.
Nanoparticulate bioceramic putty suppresses osteoclastogenesis and inflammatory bone loss in mice via inhibition of TRAF6-mediated signalling pathways: A laboratory investigation.
TOPK Inhibition Enhances the Sensitivity of Colorectal Cancer Cells to Radiotherapy by Reducing the DNA Damage Response.
Quercetin, a key active ingredient of Jianpi Zishen Xiehuo Formula, suppresses M1 macrophage polarization and platelet phagocytosis by inhibiting STAT3 activation based on network pharmacology.
African swine fever virus infection regulates pyroptosis by cleaving gasdermin A via active caspase-3 and caspase-4.
Caffeine upregulates SIRT3 expression to ameliorate astrocytes-mediated HIV-1 Tat neurotoxicity via suppression of EGR1 signaling pathway.
Insights into the effect of guanylate-binding protein 1 on the survival of Brucella intracellularly.
Expression, characterization and antivascular activity of amino acid sequence repeating collagen hexadecapeptide.
Saccharomyces boulardii alleviates allergic asthma by restoring gut microbiota and metabolic homeostasis via up-regulation of METTL3 in an m6A-dependent manner.
Mammalian IRE1α dynamically and functionally coalesces with stress granules.
Landscape of transcriptome-wide m(6)A modification in diabetic liver reveals rewiring of PI3K-Akt signaling after physical exercise.
Neutrophil extracellular traps formation may be involved in the association of propranolol with the development of portal vein thrombosis.
Isobavachin attenuates osteoclastogenesis and periodontitis-induced bone loss by inhibiting cellular iron accumulation and mitochondrial biogenesis.
Targeting NKAα1 to treat Parkinson's disease through inhibition of mitophagy-dependent ferroptosis.
Senecavirus A induces mitophagy to promote self-replication through direct interaction of 2C protein with K27-linked ubiquitinated TUFM catalyzed by RNF185.
Suppression of N-Glycosylation of Zinc Finger Protein 471 Affects Proliferation, Invasion, and Docetaxel Sensitivity of Tongue Squamous Cell Carcinoma via Regulation of c-Myc.
Obeticholic acid attenuates the intestinal barrier disruption in a rat model of short bowel syndrome.
Gut microbiota regulates the ALK5/NOX1 axis by altering glutamine metabolism to inhibit ferroptosis of intrahepatic cholangiocarcinoma cells.
OTUD1 enhances gastric cancer aggressiveness by deubiquitinating EBV-encoded protein BALF1 to stabilize the apoptosis inhibitor Bcl-2.
Altered landscape of total RNA, tRNA and sncRNA modifications in the liver and spleen of mice infected by Toxoplasma gondii.
The antidepressant effects of protein arginine methyltransferase 2 involve neuroinflammation.
13-Oxyingenol-dodecanoate inhibits the growth of non-small cell lung cancer cells by targeting ULK1.
Neuroectoderm phenotypes in a human stem cell model of O-GlcNAc transferase associated with intellectual disability.
Neobractatin induces pyroptosis of esophageal cancer cells by TOM20/BAX signaling pathway.
Silibinin is a suppressor of the metastasis-promoting transcription factor ID3.
E3 ubiquitin ligase CHIP interacts with transferrin receptor 1 for degradation and promotes cell proliferation through inhibiting ferroptosis in hepatocellular carcinoma.
H3K4me3-Mediated FOXJ2/SLAMF8 Axis Aggravates Thrombosis and Inflammation in β2GPI/Anti-β2GPI-Treated Monocytes.
Peptide Transporter 1-Mediated Dipeptide Transport Promotes Hepatocellular Carcinoma Metastasis by Activating MAP4K4/G3BP2 Signaling Axis.
Single-Nucleus Multiomic Analyses Identifies Gene Regulatory Dynamics of Phenotypic Modulation in Human Aneurysmal Aortic Root.
Microglial lipid droplet accumulation in tauopathy brain is regulated by neuronal AMPK.
Proteomics analysis of PK-15 cells infected with porcine parvovirus and the effect of PCBP1 on PPV replication.
P53 upregulation by USP7-engaging molecular glues.
Chishao - Fuzi herbal pair restore the macrophage M1/M2 balance in acute-on-chronic liver failure.
Mammalian orthoreovirus capsid protein σ3 antagonizes RLR-mediated antiviral responses by degrading MAVS.
VHL suppresses UBE3B-mediated breast tumor growth and metastasis.
ZEB2 alleviates Hirschsprung's-associated enterocolitis by promoting the proliferation and differentiation of enteric neural precursor cells via the Notch-1/Jagged-2 pathway.
Chemotherapy-induced high expression of IL23A enhances efficacy of anti-PD-1 therapy in TNBC by co-activating the PI3K-AKT signaling pathway of CTLs.
Development of a PCSK9-targeted nanoparticle vaccine to effectively decrease the hypercholesterolemia.
Graphene Far-Infrared Irradiation Can Effectively Relieve the Blood Pressure Level of Rat Untr-HT in Primary Hypertension.
Empirical analysis of lead neurotoxicity mode of action and its application in health risk assessment.
Microglial SIX2 suppresses lipopolysaccharide (LPS)-induced neuroinflammation by up-regulating FXYD2 expression.
Involvement of P2X7R-mediated microglia polarization and neuroinflammation in the response to electroacupuncture on post-stroke memory impairment.
CK1δ/ε kinases regulate TDP-43 phosphorylation and are therapeutic targets for ALS-related TDP-43 hyperphosphorylation.
Menaquinone-4 alleviates hypoxic-ischemic brain damage in neonatal rats by reducing mitochondrial dysfunction via Sirt1-PGC-1α-TFAM signaling pathway.
Diosmetin ameliorates psoriasis-associated inflammation and keratinocyte hyperproliferation by modulation of PGC-1α / YAP signaling pathway.
IRTKS contributes to the malignant progression of cervical cancer cells.
Procyanidin B1 and Coumaric Acid from Highland Barley Alleviated High-Fat-Diet-Induced Hyperlipidemia by Regulating PPARα-Mediated Hepatic Lipid Metabolism and Gut Microbiota in Diabetic C57BL/6J Mice.
FBXO43 promotes cell cycle progression in cancer cells through stabilizing SKP2.
GADD45B in the ventral hippocampal CA1 modulates aversive memory acquisition and spatial cognition.
Polystyrene microplastics induce pulmonary fibrosis by promoting alveolar epithelial cell ferroptosis through cGAS/STING signaling.
HO-1 upregulation promotes mitophagy-dependent ferroptosis in PM2.5-exposed hippocampal neurons.
Amelioration of NAFLD by sleeve gastrectomy-triggered hepatocyte regeneration in mice - experimental research.
Exosomal LncRNA TM7SF3-AU1 Aggravates White Matter Injury via MiR-702-3p/SARM1 Signaling After Subarachnoid Hemorrhage in Rats.
Rack1-mediated ferroptosis affects hindgut development in rats with anorectal malformations: Spatial transcriptome insights.
Role of formyl peptide receptor 2 in steatosis of L02 cells exposed to Mono-(2-ethylhexyl) phthalate.
The cooperative regulatory effect of the miRNA-130 family on milk fat metabolism in dairy cows.
An arabinogalactan isolated from Cynanchum atratum promotes lymphangiogenesis and lymphatic vessel remodeling to alleviate secondary lymphedema.
A dual role of ERGIC-localized Rabs in TMED10-mediated unconventional protein secretion.
MICAL-L2, as an estrogen-responsive gene, is involved in ER-positive breast cancer cell progression and tamoxifen sensitivity via the AKT/mTOR pathway.
Selective microRNA expression of exosomes from retinal pigment epithelial cells by oxidative stress.
Rocaglamide regulates iron homeostasis by suppressing hepcidin expression.
Cryptochrome 2 Suppresses Epithelial-Mesenchymal Transition by Promoting Trophoblastic Ferroptosis in Unexplained Recurrent Spontaneous Abortion.
Direct vagus nerve stimulation: A new tool to control allergic airway inflammation through α7 nicotinic acetylcholine receptor.
Insect cells of Spodoptera frugiperda support WSSV gene replication but not progeny virion assembly.
GBP2 inhibits pathological angiogenesis in the retina via the AKT/mTOR/VEGFA axis.
Electroacupuncture improves articular microcirculation and attenuates cartilage hypoxia in a male rabbit model of knee osteoarthritis.
Bushen Huoxue recipe ameliorates ovarian function via promoting BMSCs proliferation and homing to ovaries in POI mice.
Shenfu injection targets the PI3K-AKT pathway to regulate autophagy and apoptosis in acute respiratory distress syndrome caused by sepsis.
Salvia miltiorrhiza Bge. processed with porcine cardiac blood inhibited GLRX5-mediated ferroptosis alleviating cerebral ischemia-reperfusion injury.
Bergenin alleviates proliferative arterial diseases by modulating glucose metabolism in vascular smooth muscle cells.
Exploring the anti-skin inflammation substances and mechanism of Paeonia lactiflora Pall. Flower via network pharmacology-HPLC integration.
Genome sequence and cell biological toolbox of the highly regenerative, coenocytic green feather alga Bryopsis.
Active secretion of IL-33 from astrocytes is dependent on TMED10 and promotes central nervous system homeostasis.
CXXC5 drove inflammation and ovarian cancer proliferation via transcriptional activation of ZNF143 and EGR1.
Transient stimulation of TRPMLs enhance the functionality of hDPCs and facilitate hair growth in mice.
Adiponectin inhibits ROS/NLRP3 inflammatory pathway through FOXO3A to ameliorate oral submucosal fibrosis.
Luteolin alleviates cadmium-induced metabolism disorder through antioxidant and anti-inflammatory mechanisms in chicken kidney.
Oridonin promotes RSL3-induced ferroptosis in breast cancer cells by regulating the oxidative stress signaling pathway JNK/Nrf2/HO-1.
Genipin improves obesity through promoting bile secretion and changing bile acids composition in diet-induced obese rats.
ATPR induces acute promyelocytic leukemia cells differentiation and cycle arrest via the lncRNA CONCR/DDX11/PML-RARα signaling axis.
Stigmasterol Activates the mTOR Signaling Pathway by Inhibiting ORP5 Ubiquitination to Promote Milk Synthesis in Bovine Mammary Epithelial Cells.
Narirutin mitigates dextrose sodium sulfate-induced colitis in mice by modulating intestinal flora.
Podophyllotoxin via SIRT1/PPAR /NF-κB axis induced cardiac injury in rats based on the toxicological evidence chain (TEC) concept.
Overexpression of transcription factor TBX5 inhibits the activation of YAP1-TEAD1 pathway to promote ferroptosis in lung cancer cells.
Calorie Restriction Attenuates Memory Impairment and Reduces Neuroinflammation in Obese Aged Rats.
Fasudil attenuates oxidative stress-induced partial epithelial-mesenchymal transition of tubular epithelial cells in hyperuricemic nephropathy via activating Nrf2.
Identification of activating transcription factor 6 (ATF6) as a novel prognostic biomarker and potential target in oral squamous cell carcinoma.
Comprehensive bioinformatics analysis and cell line experiments revealed the important role of CDCA3 in sarcoma.
Discovery of a Covalent Inhibitor That Overcame Resistance to Venetoclax in AML Cells Overexpressing BFL-1.
AQP1 Deficiency Drives Phthalate-Induced Epithelial Barrier Disruption through Intestinal Inflammation.
Caveolin-1 scaffolding domain-derived peptide enhances erectile function by regulating oxidative stress, mitochondrial dysfunction, and apoptosis of corpus cavernosum smooth muscle cells in rats with cavernous nerve injury.
Biphasic regulation of miR-17∼92 transcription during hypoxia: roles of HIF1 and p53 hyperphosphorylation at ser15.
Trailblazing in adjuvant research: succinate's uncharted territory with neutrophils.
Inhibition of TREM-1 alleviates neuroinflammation by modulating microglial polarization via SYK/p38MAPK signaling pathway after traumatic brain injury.
Study on the effect of protein lysine lactylation modification in macrophages on inhibiting periodontitis in rats.
Single-Cell RNA Transcriptome of the Human Endometrium Reveals Epithelial Characterizations Associated with Recurrent Implantation Failure.
Allicin ameliorates sepsis-induced acute kidney injury through Nrf2/HO-1 signaling pathway.
Soy isoflavone genistein attenuates the efficacy of immune checkpoint therapy in C57BL/6 mice inoculated with B16F1 melanoma and a high PD-L1 expression level reflects tumor resistance.
TAPI-1 Exhibits Anti-tumor Efficacy in Human Esophageal Squamous Cell Carcinoma Cells via Suppression of NF-κB Signaling Pathway.
Mycobacterium tuberculosis PE_PGRS45 (Rv2615c) Promotes Recombinant Mycobacteria Intracellular Survival via Regulation of Innate Immunity, and Inhibition of Cell Apoptosis.
A novel AluYb8 insertion-associated non-coding RNA, lncMUTYH, impairs mitochondrial function and dampens the M2-like polarization of macrophages.
Muscle fibre transition and transcriptional changes of horse skeletal muscles during traditional Mongolian endurance training.
Hsa_circ_0001583 fuels bladder cancer metastasis by promoting staphylococcal nuclease and tudor domain containing 1-mediated MicroRNA decay.
PGAM5 exacerbates acute renal injury by initiating mitochondria-dependent apoptosis by facilitating mitochondrial cytochrome c release.
Pb induces the release of CXCL10 and CCL2 chemokines via mtROS/NF-κB activation in BV-2 cells.
Let-7a-5p abrogates progression of papillary thyroid carcinoma cells by decreasing nuclear receptor subfamily 6 group a member 1-mediated lipogenesis.
Serum amyloid A aggravates endotoxin-induced ocular inflammation through the regulation of retinal microglial activation.
CD30 plays a role in T-dependent immune response and T cell proliferation.
Taxifolin-mediated Nrf2 activation ameliorates oxidative stress and apoptosis for the treatment of glucocorticoid-induced osteonecrosis of the femoral head.
PCB126 impairs human sperm functions by affecting post-translational modifications and mitochondrial functions.
Ubiquitin ligase NEDD4 promotes the proliferation of hepatocellular carcinoma cells through targeting PCDH17 protein for ubiquitination and degradation.
SynCAM1 deficiency in the hippocampal parvalbumin interneurons contributes to sevoflurane-induced cognitive impairment in neonatal rats.
TRPC3 signalling contributes to the biogenesis of extracellular vesicles.
Exosome‑delivered miR‑486‑3p inhibits the progression of osteosarcoma via sponging CircKEAP1/MARCH1 axis components.
Hematoporphyrin derivative photodynamic therapy induces apoptosis and suppresses the migration of human esophageal squamous cell carcinoma cells by regulating the PI3K/AKT/mTOR signaling pathway.
Astragaloside IV promotes exosome secretion of endothelial progenitor cells to regulate PI3KR2/SPRED1 signaling and inhibit pyroptosis of diabetic endothelial cells.
Gut microbial metabolite facilitates colorectal cancer development via ferroptosis inhibition.
Oxidative stress is involved in immunosuppression and macrophage regulation in glioblastoma.
Effects of hazelnut soluble dietary fiber on lipid-lowering and gut microbiota in high-fat-diet-fed rats.
Grass carp superoxide dismutases exert antioxidant function and inhibit autophagy to promote grass carp reovirus (GCRV) replication.
Vasculogenic mimicry-associated novel gene signature predicted prognosis and response to immunotherapy in lung adenocarcinoma.
TESC acts as a prognostic factor and promotes epithelial-mesenchymal transition progression in esophageal squamous carcinoma.
NAMPT regulates mitochondria function and lipid metabolism during porcine oocyte maturation.
Hydrogen sulfide attenuates depression-like behaviours in Parkinson's disease model rats by improving synaptic plasticity in a hippocampal Warburg effect-dependent manner.
Malonate differentially affects cell survival and confers chemoresistance in cancer cells via the induction of p53-dependent autophagy.
Clemastine-induced enhancement of hippocampal myelination alleviates memory impairment in mice with chronic pain.
Hepatocyte growth factor attenuates high glucose-disturbed mitochondrial dynamics in podocytes by decreasing ARF6-dependent DRP1 translocation.
Myo6 mediates osteoclast function and is essential for joint damage in collagen-induced arthritis.
CARD9 deficiency aggravated nonalcoholic steatohepatitis in mice through increasing inflammatory response.
Melatonin inhibits fibroblast cell functions and hypertrophic scar formation by enhancing autophagy through the MT2 receptor-inhibited PI3K/Akt /mTOR signaling.
Eupatilin inhibits xanthine oxidase in vitro and attenuates hyperuricemia and renal injury in vivo.
6-Gingerol regulates triglyceride and cholesterol biosynthesis to improve hepatic steatosis in MAFLD by activating the AMPK-SREBPs signaling pathway.
Berberine exerts antidepressant effects in vivo and in vitro through the PI3K/AKT/CREB/BDNF signaling pathway.
Exercise ameliorating myocardial injury in type 2 diabetic rats by inhibiting excessive mitochondrial fission involving increased irisin expression and AMP-activated protein kinase phosphorylation.
Brassisterol A, a new ergosterol from co-cultivation of fungi attenuates neuroinflammation via targeting NLRP3/caspase-1/GSDMD pathway.
ARID5B-mediated LINC01128 epigenetically activated pyroptosis and apoptosis by promoting the formation of the BTF3/STAT3 complex in β2GPI/anti-β2GPI-treated monocytes.
The homologous tumor-derived-exosomes loaded with miR-1270 selectively enhanced the suppression effect for colorectal cancer cells.
Taxifolin inhibits melanoma proliferation/migration impeding USP18/Rac1/JNK/β-catenin oncogenic signaling.
Radix Astragali decoction improves liver regeneration by upregulating hepatic expression of aquaporin-9.
Targeting HSP70 chaperones by rhein sensitizes liver cancer to artemisinin derivatives.
Hyperoxia-induced airflow restriction and Renin-Angiotensin System expression in a bronchopulmonary dysplasia mouse model.
Branched-Chain Amino Acid Accumulation Fuels the Senescence-Associated Secretory Phenotype.
let-7g sensitized liver cancer cells to 5-fluorouracil by downregulating ABCC10 expression.
Drp1 regulated PINK1-dependent mitophagy protected duck follicular granulosa cells from acute heat stress injury.
Resveratrol alleviates heat-stress-induced impairment of the jejunal mucosa through TLR4/MAPK signaling pathway in black-boned chicken.
Gut microbiota regulates host melatonin production through epithelial cell MyD88.
SH3RF2 contributes to cisplatin resistance in ovarian cancer cells by promoting RBPMS degradation.
The E3 ligase NEURL3 suppresses epithelial-mesenchymal transition and metastasis in nasopharyngeal carcinoma by promoting vimentin degradation.
Novel lissencephaly-associated NDEL1 variant reveals distinct roles of NDE1 and NDEL1 in nucleokinesis and human cortical malformations.
Near-infrared-responsive GE11-CuS@Gal nanoparticles as an intelligent drug release system for targeting therapy against oral squamous cell carcinoma.
Engineered exosomes mediated targeted delivery of neuroprotective peptide NR2B9c for the treatment of traumatic brain injury.
Gestational exposure to 1-NP induces ferroptosis in placental trophoblasts via CYP1B1/ERK signaling pathway leading to fetal growth restriction.
Diosgenin alters LPS-induced macrophage polarization by activating PPARγ/NF-κB signaling pathway.
Knockdown of Smox protects the integrity of the blood-brain barrier through antioxidant effect and Nrf2 pathway activation in stroke.
A framework for Frizzled-G protein coupling and implications to the PCP signaling pathways.
TIMELESS promotes reprogramming of glucose metabolism in oral squamous cell carcinoma.
TET2-mediated tumor cGAS triggers endothelial STING activation to regulate vasculature remodeling and anti-tumor immunity in liver cancer.
Adipose-derived stem cell exosomes promote tumor characterization and immunosuppressive microenvironment in breast cancer.
Methionine Promotes Milk Synthesis through the BRCC36-BRG1-mTOR Signaling Axis in Mammary Epithelial Cells.
A network pharmacology approach and experimental validation to investigate the anticancer mechanism of Qi-Qin-Hu-Chang formula against colitis-associated colorectal cancer through induction of apoptosis via JNK/p38 MAPK signaling pathway.
Huaier suppresses cisplatin resistance in non-small cell lung cancer by inhibiting the JNK/JUN/IL-8 signaling pathway.
Prunella vulgaris L. attenuates gut dysbiosis and endotoxin leakage against alcoholic liver disease.
The protective effect of apolipoprotein H in paediatric sepsis.
A peptide from the Japanese encephalitis virus failed to induce the production of anti-N-methyl-d-aspartate receptor antibodies via molecular mimicry in mice.
Huc-MSC-derived exosomal miR-144 alleviates inflammation in LPS-induced preeclampsia-like pregnant rats via the FosB/Flt-1 pathway.
TET2-mediated ECM1 hypomethylation promotes the neovascularization in active proliferative diabetic retinopathy.
Porcine Intestinal Mucosal Peptides Target Macrophage-Modulated Inflammation and Alleviate Intestinal Homeostasis in Dextrose Sodium Sulfate-Induced Colitis in Mice.
Antioxidative Sirt1 and the Keap1-Nrf2 Signaling Pathway Impair Inflammation and Positively Regulate Autophagy in Murine Mammary Epithelial Cells or Mammary Glands Infected with Streptococcus uberis.
Deciphering the tumor-suppressive role of PSMB9 in melanoma through multi-omics and single-cell transcriptome analyses.
Phosphorylated α-synuclein deposited in Schwann cells interacting with TLR2 mediates cell damage and induces Parkinson's disease autonomic dysfunction.
Endoplasmic reticulum aminopeptidase 2 regulates CD4(+) T cells pyroptosis in rheumatoid arthritis.
SHMT2 promotes papillary thyroid cancer metastasis through epigenetic activation of AKT signaling.
Morroniside-mediated mitigation of stem cell and endothelial cell dysfunction for the therapy of glucocorticoid-induced osteonecrosis of the femoral head.
Gypenoside XLIX attenuates sepsis-induced splenic injury through inhibiting inflammation and oxidative stress.
TDP43/HDAC6/Prdx1 signaling pathway participated in the cognitive impairment of obstructive sleep apnea via regulating inflammation and oxidative stress.
Panax notoginseng saponin R1 improves glucocorticoid-inhibited airway epithelium repair via glucocorticoid receptor β.
Cold-inducible RNA-binding protein induces inflammatory responses via NF-κB signaling pathway in normal human bronchial epithelial cells infected with streptococcus pneumoniae.
METTL1 mediated tRNA m(7)G modification promotes leukaemogenesis of AML via tRNA regulated translational control.
Integrin β1-rich extracellular vesicles of kidney recruit Fn1+ macrophages to aggravate ischemia-reperfusion-induced inflammation.
Exogenous carbon monoxide promotes GPX4-dependent ferroptosis through ROS/GSK3β axis in non-small cell lung cancer.
LDLR is used as a cell entry receptor by multiple alphaviruses.
Targeting gut microbial nitrogen recycling and cellular uptake of ammonium to improve bortezomib resistance in multiple myeloma.
Pharmaceutical targeting of OTUB2 sensitizes tumors to cytotoxic T cells via degradation of PD-L1.
FOXP3(+) regulatory T cell perturbation mediated by the IFNγ-STAT1-IFITM3 feedback loop is essential for anti-tumor immunity.
YTHDF3 modulates the Cbln1 level by recruiting BTG2 and is implicated in the impaired cognition of prenatal hypoxia offspring.
Hexamethylene amiloride synergizes with venetoclax to induce lysosome-dependent cell death in acute myeloid leukemia.
Phosphorylation-dependent membraneless organelle fusion and fission illustrated by postsynaptic density assemblies.
Loss of LBP triggers lipid metabolic disorder through H3K27 acetylation-mediated C/EBPβ- SCD activation in non-alcoholic fatty liver disease.
MTFR2-dependent mitochondrial fission promotes HCC progression.
The SIRT1/Nrf2 signaling pathway mediates the anti-pulmonary fibrosis effect of liquiritigenin.
Metabolic regulation of homologous recombination repair by MRE11 lactylation.
Transcription factor Sp1 transcriptionally enhances GSDME expression for pyroptosis.
USP29 activation mediated by FUBP1 promotes AURKB stability and oncogenic functions in gastric cancer.
Egr-1 is a key regulator of the blood-brain barrier damage induced by meningitic Escherichia coli.
Antitumor Effect of Platinum-Modified STING Agonist MSA-2.
MicroRNA-218-5p-Ddx41 axis restrains microglia-mediated neuroinflammation through downregulating type I interferon response in a mouse model of Parkinson's disease.
Cell surface GRP78: A potential therapeutic target for high glucose-induced endothelial injury.
Resveratrol protected against the development of endometriosis by promoting ferroptosis through miR-21-3p/p53/SLC7A11 signaling pathway.
Celastrol-loaded bovine serum albumin nanoparticles target inflamed neutrophils for improved rheumatoid arthritis therapy.
Multi-monoubiquitylation controls VASP-mediated actin dynamics.
MicroRNA-146a-loaded magnesium silicate nanospheres promote bone regeneration in an inflammatory microenvironment.
Identification and Validation of a Prognostic Signature Derived from the Cancer Stem Cells for Oral Squamous Cell Carcinoma.
From Hit to Lead: Structure-Based Optimization of Novel Selective Inhibitors of Receptor-Interacting Protein Kinase 1 (RIPK1) for the Treatment of Inflammatory Diseases.
PHB2 promotes SHIP2 ubiquitination via the E3 ligase NEDD4 to regulate AKT signaling in gastric cancer.
Gentiopicroside inhibits the progression of gastric cancer through modulating EGFR/PI3K/AKT signaling pathway.
Orange-spotted grouper nervous necrosis virus-encoded protein A induces interferon expression via RIG-I/MDA5-MAVS-TBK1-IRF3 signaling in fish cells.
Podophyllotoxin-mediated neurotoxicity via the microbiota-gut-brain axis in SD rats based on the toxicological evidence chain (TEC) concept.
Acylated Ghrelin Activates PI3K/mTOR Signaling Pathway by Promoting ThPOK Acetylation to Promote Milk Fat Synthesis in Bovine Mammary Epithelial Cells.
Chinese herbal medicine alleviates autophagy and apoptosis in ovarian granulosa cells induced by testosterone through PI3K/AKT1/FOXO1 pathway.
Xiaobanxia decoction alleviates chemotherapy-induced nausea and vomiting by inhibiting GSDME-mediated pyroptosis.
Inhibitory effect of Lonicera japonica-derived exosomal miR2911 on human papilloma virus.
Xiao-Ban-Xia decoction mitigates cisplatin-induced emesis via restoring PINK1/Parkin mediated mitophagy deficiency in a rat pica model.
ETV7 promotes colorectal cancer progression through upregulation of IFIT3.
ALCAT1-mediated abnormal cardiolipin remodelling promotes mitochondrial injury in podocytes in diabetic kidney disease.
PFKFB3 promotes endometriosis cell proliferation via enhancing the protein stability of β-catenin.
Blocking the interaction between circTNRC18 and LIN28A promotes trophoblast epithelial-mesenchymal transformation and alleviates preeclampsia.
Aging-related NOX4-Nrf2 redox imbalance increases susceptibility to cisplatin-induced acute kidney injury by regulating mitophagy.
Parkin-mediated mitophagy is a potential treatment for oxaliplatin-induced peripheral neuropathy.
Low beauvericin concentrations promote PC-12 cell survival under oxidative stress by regulating lipid metabolism and PI3K/AKT/mTOR signaling.
Synergistic anticancer effect by targeting CDK2 and EGFR-ERK signaling.
Proteolysis Targeting Chimeras (PROTACs) based on celastrol induce multiple protein degradation for triple-negative breast cancer treatment.
Rapid turnover of CTLA4 is associated with a complex architecture of reversible ubiquitylation.
The E3 ubiquitin ligase TRIM9 regulates synaptic function and actin dynamics.
Demethylase FTO-Mediated m6A Modification of lncRNA MEG3 Activates Neuronal Pyroptosis via NLRP3 Signaling in Cerebral Ischemic Stroke.
LncRNA JHDM1D-AS1 promotes osteogenic differentiation of periodontal ligament cells by targeting miR-532-5p to activate IGF1R signaling.
Omega-3 polyunsaturated fatty acids and its metabolite 12-HEPE rescue busulfan disrupted spermatogenesis via target to GPR120.
Pyruvate kinase M2 regulates kidney fibrosis through pericyte glycolysis during the progression from acute kidney injury to chronic kidney disease.
Helicobacter pylori CagA-mediated ether lipid biosynthesis promotes ferroptosis susceptibility in gastric cancer.
A Study on the Acquisition and Identification of Beige Adipocytes and Exosomes as Well as Their Inflammatory Regulation by Promoting Macrophage Polarization.
Overexpressed FAM111B degrades GSDMA to promote esophageal cancer tumorigenesis and cisplatin resistance.
NQO1 Mediates Lenvatinib Resistance by Regulating ROS-induced Apoptosis in Hepatocellular Carcinoma.
Synergistic effect of adavosertib and fimepinostat on acute myeloid leukemia cells by enhancing the induction of DNA damage.
The protein kinase A signaling pathway mediates the effect of electroacupuncture on excessive contraction of the bladder detrusor in a rat model of neurogenic bladder.
Hsp90 β is critical for the infection of severe fever with thrombocytopenia syndrome virus.
The role and mechanism of RIPK1 in vascular endothelial dysfunction in chronic kidney disease.
Oral administration of punicalagin attenuates imiquimod-induced psoriasis by reducing ROS generation and inflammation via MAPK/ERK and NF-κB signaling pathways.
[Adipose-derived stem cell-derived exosomes regulate Th2/Treg balance in peripheral blood of AR patients through the mTOR pathway].
Serabelisib regulates GSDMD-mediated pyroptosis, apoptosis and migration of hepatoma cells via the PI3K/Akt/E-cadherin signaling pathway.
Tasquinimod enhances the sensitivity of ovarian cancer cells to cisplatin by regulating the Nur77-Bcl-2 apoptotic pathway.
Targeted transplantation of engineered mitochondrial compound promotes functional recovery after spinal cord injury by enhancing macrophage phagocytosis.
Comprehensive analysis of PSMD family members and validation of PSMD9 as a potential therapeutic target in human glioblastoma.
CIA-II is associated with lower-grade glioma survival and cell proliferation.
Tanshinone IIA, a component of the self-made Xiao-Yin decoction, ameliorates psoriasis by inhibiting IL-17/IL-23 and PTGS2/NF-κB/AP-1 pathways.
miR‑186‑5p regulates the inflammatory response of chronic obstructive pulmonary disorder by targeting HIF‑1α.
Identification of differentially expressed genes associated with ferroptosis in Crohn's disease.
JAM2 is a prognostic biomarker and inhibits proliferation, metastasis and epithelial-mesenchymal transition in lung adenocarcinoma.
A dihydromyricetin-loaded phellinus igniarius polysaccharide/l-arginine modified chitosan-based hydrogel for promoting wound recovery in diabetic mice via JNK and TGF-β/Smad signaling pathway.
Natural isoflavone glabridin targets PI3Kγ as an adjuvant to increase the sensitivity of MDA-MB-231 to tamoxifen and DU145 to paclitaxel.
Repression of YEATS2 induces cellular senescence in hepatocellular carcinoma and inhibits tumor growth.
Upregulation of TRIM16 mitigates doxorubicin-induced cardiotoxicity by modulating TAK1 and YAP/Nrf2 pathways in mice.
PCSK9 regulates myofibroblast transformation through the JAK2/STAT3 pathway to regulate fibrosis after myocardial infarction.
Gestational exposure to bisphenol AF causes endocrine disorder of corpus luteum by altering ovarian SIRT-1/Nrf2/NF-kB expressions and macrophage proangiogenic function in mice.
Fructus Ligustri Lucidi inhibits ferroptosis in ovariectomy‑induced osteoporosis in rats via the Nrf2/HO‑1 signaling pathway.
BAP18 acting as a novel peroxisome proliferator-activated receptor α co-regulator contributes to hepatocellular carcinoma progression.
Palmitic acid and trans-4-hydroxy-3-methoxycinnamate, the active ingredients of Yaobishu formula, reduce inflammation and pain by regulating gut microbiota and metabolic changes after lumbar disc herniation to activate autophagy and the Wnt/β-catenin pathway.
Farnesoid X receptor overexpression prevents hepatic steatosis through inhibiting AIM2 inflammasome activation in nonalcoholic fatty liver disease.
Fluorene-9-bisphenol exposure damages the testis in mice through a novel mechanism of ferroptosis.
Human umbilical cord-derived mesenchymal stem cells ameliorate liver fibrosis by improving mitochondrial function via Slc25a47-Sirt3 signaling pathway.
HDAC6-MYCN-CXCL3 axis mediates allergic inflammation and is necessary for allergic inflammation-promoted cellular interactions.
Extra villous trophoblast-derived PDL1 can ameliorate macrophage inflammation and promote immune adaptation associated with preeclampsia.
Gestational Diabetes Mellitus Remodels the Fetal Brain Fatty Acid Profile Through Placenta-Brain Lipid Axis in C57BL/6J Mice.
The involvement of RNA N6-methyladenosine and histone methylation modification in decidualization and endometriosis-associated infertility.
KLF4 interacts with TXNIP to modulate the pyroptosis in ulcerative colitis via regulating NLRP3 signaling.
Sustainable inflammatory activation following spinal cord injury is driven by thrombin-mediated dynamic expression of astrocytic chemokines.
Coenzyme Q10 Protects Against Hyperlipidemia-Induced Osteoporosis by Improving Mitochondrial Function via Modulating miR-130b-3p/PGC-1α Pathway.
A Novel Cargo Delivery System-AnCar-Exo(LaIMTS) Ameliorates Arthritis via Specifically Targeting Pro-Inflammatory Macrophages.
METTL16 inhibits papillary thyroid cancer tumorigenicity through m(6)A/YTHDC2/SCD1-regulated lipid metabolism.
Balancing macrophage polarization via stem cell-derived apoptotic bodies for diabetic wound healing.
MTHFD1 regulates the NADPH redox homeostasis in MYCN-amplified neuroblastoma.
Collecting duct NCOR1 controls blood pressure by regulating mineralocorticoid receptor.
Whey Protein Peptide Pro-Glu-Trp Ameliorates Hyperuricemia by Enhancing Intestinal Uric Acid Excretion, Modulating the Gut Microbiota, and Protecting the Intestinal Barrier in Rats.
A mouse model to distinguish NLRP6-mediated inflammasome-dependent and -independent functions.
Identification of a potential signature to predict the risk of postmenopausal osteoporosis.
MicroRNA-148a-3p suppresses the glycolysis and Cell proliferation by targeting transmembrane protein 54 in liver cancer.
JMJD3 regulate H3K27me3 modification via interacting directly with TET1 to affect spermatogonia self-renewal and proliferation.
Warm Acupuncture Reduces Pain and Inflammation in Rats with Lumbar Disc Herniation Induced by Autologous Nucleus Pulposus Transplantation via Regulating p38MAPK/NF-κB Pathway.
Preliminary exploration of the potential biological functions and prognosis values of RAB4B in pan-cancer combing with experimental validation in BLCA.
The ARID1A-METTL3-m6A axis ensures effective RNase H1-mediated resolution of R-loops and genome stability.
Human YKT6 forms priming complex with STX17 and SNAP29 to facilitate autophagosome-lysosome fusion.
p53 promotes antiviral innate immunity by driving hexosamine metabolism.
ALOX5 drives the pyroptosis of CD4(+) T cells and tissue inflammation in rheumatoid arthritis.
Nucleoporin Seh1 controls murine neocortical development via transcriptional repression of p21 in neural stem cells.
EGR1 mediates MDR1 transcriptional activity regulating gemcitabine resistance in pancreatic cancer.
S-nitrosothiol homeostasis maintained by ADH5 facilitates STING-dependent host defense against pathogens.
NINJ1 mediates inflammatory cell death, PANoptosis, and lethality during infection conditions and heat stress.
DIA proteomics analysis reveals the mechanism of folic acid-induced acute kidney injury and the effects of icariin.
Ameliorative Effect of Coenzyme Q10 on Phenotypic Transformation in Human Smooth Muscle Cells with FBN1 Knockdown.
Synergistic suppression of ovarian cancer by combining NRF2 and GPX4 inhibitors: in vitro and in vivo evidence.
Protective effects of Pt-N-C single-atom nanozymes against myocardial ischemia-reperfusion injury.
Discovery of D25, a Potent and Selective MNK Inhibitor for Sepsis-Associated Acute Spleen Injury.
Development of Potent MALT1 Inhibitors Featuring a Novel "2-Thioxo-2,3-dihydrothiazolo[4,5-d]pyrimidin-7(6H)-one" Scaffold for the Treatment of B Cell Lymphoma.
The Parkinson's disease related mutant VPS35 (D620N) amplifies the LRRK2 response to endolysosomal stress.
Nel-like Molecule Type 1 Combined with Gold Nanoparticles Modulates Macrophage Polarization, Osteoclastogenesis, and Oral Microbiota in Periodontitis.
HMGA1 drives chemoresistance in esophageal squamous cell carcinoma by suppressing ferroptosis.
[Protective effect of FAK inhibitor PF-562271 against human umbilical vein endothelial cell injury induced by aging platelets].
The pathogenicity of vancomycin-resistant Enterococcus faecalis to colon cancer cells.
P21 resists ferroptosis in osteoarthritic chondrocytes by regulating GPX4 protein stability.
SYNJ2BP ameliorates intervertebral disc degeneration by facilitating mitochondria-associated endoplasmic reticulum membrane formation and mitochondrial Zn(2+) homeostasis.
Ezrin inhibition alleviates oxidative stress and pyroptosis via regulating TRPML1-calcineurin axis mediated enhancement of autophagy in spinal cord injury.
A Curcumin-Decorated Nanozyme with ROS Scavenging and Anti-Inflammatory Properties for Neuroprotection.
Transcriptotype-Driven Discovery of Apigenin as a Therapy against Cholestatic Liver Fibrosis: Through Inhibition of PANoptosis and Following Type-I Interferon Responses.
The clustering status of detached gastric cancer cells inhibits anoikis-induced ferroptosis to promote metastatic colonization.
Tumorigenesis of basal muscle invasive bladder cancer was mediated by PTEN protein degradation resulting from SNHG1 upregulation.
Teadenol B as a Component of Microorganism-Fermented Tea Extract Inhibited Breast Cancers by Promoting Autophagy.
KLF2 controls proliferation and apoptosis of human spermatogonial stem cells via targeting GJA1.
Investigating HMGB1 as a potential serum biomarker for early diabetic nephropathy monitoring by quantitative proteomics.
Inhibition of RIPK1 alleviating vascular smooth muscle cells osteogenic transdifferentiation via Runx2.
Total flavonoids of Astragalus protects glomerular filtration barrier in diabetic kidney disease.
ALKBH5 promotes the development of lung adenocarcinoma by regulating the polarization of M2 macrophages through CDCA4.
Serine synthesis sustains macrophage IL-1β production via NAD(+)-dependent protein acetylation.
Scutellarin targets Wnt5a against zearalenone-induced apoptosis in mouse granulosa cells in vitro and in vivo.
Lysine demethylase KDM3A alleviates hyperoxia-induced bronchopulmonary dysplasia in mice by promoting ETS1 expression.
The levels of IL1RN is a factor influencing the onset of rheumatoid arthritis in non-alcoholic fatty liver disease.
L-lysine supplementation attenuates experimental autoimmune hepatitis in a chronic murine model.
PEDV inhibits HNRNPA3 expression by miR-218-5p to enhance cellular lipid accumulation and promote viral replication.
Role of TFEB-autophagy lysosomal pathway in palmitic acid induced renal tubular epithelial cell injury.
Exercise enhances placental labyrinth trophoblast development by activation of PGC-1α and FNDC5/irisin†.
DNA hypomethylation-mediated upregulation of GADD45B facilitates airway inflammation and epithelial cell senescence in COPD.
OXCT1 functions as a succinyltransferase, contributing to hepatocellular carcinoma via succinylating LACTB.
POH1 induces Smad3 deubiquitination and promotes lung cancer metastasis.
TLR9 activation induces immunosuppression and tumorigenesis via PARP1/PD-L1 signaling pathway in oral squamous cell carcinoma.
Therapeutic application of human type 2 innate lymphoid cells via induction of granzyme B-mediated tumor cell death.
Leptin receptor deficiency impedes metabolic surgery related-weight loss through inhibition of energy expenditure in db/db mice.
Tabersonine enhances cisplatin sensitivity by modulating Aurora kinase A and suppressing epithelial-mesenchymal transition in triple-negative breast cancer.
Nanoparticles transfected with plasmid-encoded lncRNA-OIP5-AS1 inhibit renal ischemia-reperfusion injury in mice via the miR-410-3p/Nrf2 axis.
Ginsenoside Rg1 mitigates cerebral ischaemia/reperfusion injury in mice by inhibiting autophagy through activation of mTOR signalling.
NOD2 contributes to Parvimonas micra-induced bone resorption in diabetic rats with experimental periodontitis.
Novel isobavachalcone derivatives induce apoptosis and necroptosis in human non-small cell lung cancer H1975 cells.
Ivacaftor attenuates gentamicin-induced ototoxicity through the CFTR-Nrf2-HO1/NQO1 pathway.
Integration of single-nucleus and exosome RNA sequencing dissected inter-cellular communication and biomarkers in pancreatic ductal adenocarcinoma.
Downregulation of ABLIM3 confers to the metastasis of neuroblastoma via regulating the cell adhesion molecules pathway.
Study on chromatin regulation patterns of expression vectors in the PhiC31 integration site.
Molecular mechanism of infectious spleen and kidney necrosis virus in manipulating the hypoxia-inducible factor pathway to augment virus replication.
miR-10b-5p promotes tumor growth by regulating cell metabolism in liver cancer via targeting SLC38A2.
Deficiency of betaine-homocysteine methyltransferase activates glucose-6-phosphate dehydrogenase (G6PD) by decreasing arginine methylation of G6PD in hepatocellular carcinogenesis.
The combination of Butyricicoccus pullicaecorum and 3-hydroxyanthranilic acid prevents postmenopausal osteoporosis by modulating gut microbiota and Th17/Treg.
Serum IL-24 combined with CA125 as screening and prognostic biomarkers for NSCLC.
Empagliflozin and liraglutide ameliorate HFpEF in mice via augmenting the Erbb4 signaling pathway.
Maresin1 alleviates neuroinflammation by inhibiting caspase-3/ GSDME-mediated pyroptosis in mice cerebral ischemia-reperfusion model.
Identifying SLC2A6 as the novel protective factor in breast cancer by TP53-related genes affecting M1 macrophage infiltration.
Blue light irradiation suppresses oral squamous cell carcinoma through induction of endoplasmic reticulum stress and mitochondrial dysfunction.
Homoplantaginin alleviates intervertebral disc degeneration by blocking the NF-κB/MAPK pathways via binding to TAK1.
FeP-Based Nanotheranostic Platform for Enhanced Phototherapy/Ferroptosis/Chemodynamic Therapy.
Lipoamide Attenuates Hypertensive Myocardial Hypertrophy Through PI3K/Akt-Mediated Nrf2 Signaling Pathway.
Hypobaric hypoxia causes low fecundity in zebrafish parents and impairment of skeletal development in zebrafish embryos and rat offspring.
Reversing MET-Mediated Resistance in Oncogene-Driven NSCLC by MET-Activated Wnt Condensative Prodrug.
Loss of NLRP6 expression increases the severity of intestinal injury after syngeneic hematopoietic stem cell transplantation.
Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer.
Recharacterization of RSL3 reveals that the selenoproteome is a druggable target in colorectal cancer.
Nicotinamide riboside ameliorates survival time and motor dysfunction in an MPTP-Induced Parkinson's disease zebrafish model through effects on glucose metabolism and endoplasmic reticulum stress.
Neural epidermal growth factor-like 1 protein (Nell-1) alleviates periodontal tissue destruction in periodontitis by regulating the ratio of M2/M1 macrophage phenotypes.
A novel oral TLR7 agonist orchestrates immune response and synergizes with PD-L1 blockade via type I IFN pathway in lung cancer.
Azithromycin regulates Mettl3-mediated NF-κB pathway to enhance M2 polarization of RAW264.7 macrophages and attenuate LPS-triggered cytotoxicity of MLE-12 alveolar cells.
Diosgenin attenuates nonalcoholic hepatic steatosis through the hepatic SIRT1/PGC-1α pathway.
Nrf2 expression, mitochondrial fission, and neuronal apoptosis in the prefrontal cortex of methamphetamine abusers and rats.
The mechanism of extracellular CypB promotes glioblastoma adaptation to glutamine deprivation microenvironment.
Fusobacterium nucleatum induces oxaliplatin resistance by inhibiting ferroptosis through E-cadherin/β-catenin/GPX4 axis in colorectal cancer.
Neuritin promotes autophagic flux by inhibiting the cGAS-STING pathway to alleviate brain injury after subarachnoid haemorrhage.
Altered vacuole membrane protein 1 (VMP1) expression is associated with increased NLRP3 inflammasome activation and mitochondrial dysfunction.
Insertion of a neomycin selection cassette in the Amigo1 locus alters gene expression in the olfactory epithelium leading to region-specific defects in olfactory receptor neuron development.
ZFP541 and KCTD19 regulate chromatin organization and transcription programs for male meiotic progression.
Crosstalk between autophagy and inflammasomes in ricin-induced inflammatory injury.
Vinpocetine represses the progression of nonalcoholic steatohepatitis in mice by mediating inflammasome components via NF-κB signaling.
Upregulation of UHRF1 Promotes PINK1-mediated Mitophagy to Alleviates Ferroptosis in Diabetic Nephropathy.
Britannin as a novel NLRP3 inhibitor, suppresses inflammasome activation in macrophages and alleviates NLRP3-related diseases in mice.
Mechanisms of Dangua Fang in multi-target and multi-method regulation of glycolipid metabolism based on phosphoproteomics.
Propofol-induced LINC01133 inhibits the progression of colorectal cancer via miR-186-5p/NR3C2 axis.
Polystyrene microplastics mediate cell cycle arrest, apoptosis, and autophagy in the G2/M phase through ROS in grass carp kidney cells.
Efficient gene delivery by multifunctional star poly (β-amino ester)s into difficult-to-transfect macrophages for M1 polarization.
Lysosomal destabilization: A missing link between pathological calcification and osteoarthritis.
Construction of a versatile fusion protein for targeted therapy and immunotherapy.
Novel α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor (AMPAR) potentiator LT-102: A promising therapeutic agent for treating cognitive impairment associated with schizophrenia.
Integrated transcriptomic and proteomic profiling reveals the key molecular signatures of brain endothelial reperfusion injury.
Isorhamnetin Downregulates MMP2 and MMP9 to Inhibit Development of Rheumatoid Arthritis through SRC/ERK/CREB Pathway.
Oxidative stress-induced changes in the transcriptomic profile of extracellular vesicles.
Abnormal activation of RFC3, A YAP1/TEAD downstream target, promotes gastric cancer progression.
Cathepsin L prevents the accumulation of alpha-synuclein fibrils in the cell.
Investigation of GPR143 as a promising novel marker for the progression of skin cutaneous melanoma through bioinformatic analyses and cell experiments.
HBI-8000 improves heart failure with preserved ejection fraction via the TGF-β1/MAPK signalling pathway.
Retinoic acid induced specific changes in the phosphoproteome of C17.2 neural stem cells.
Lipin-1 deficiency deteriorates defect of fatty acid β-oxidation and lipid-related kidney damage in diabetic kidney disease.
Polyvinyl alcohol/carboxymethyl chitosan-based hydrogels loaded with taxifolin liposomes promote diabetic wound healing by inhibiting inflammation and regulating autophagy.
A Pt(II) complex bearing N-heterocycle ring induced ferroptotic cell death in ovarian cancer.
Excessive processing and acetylation of OPA1 aggravate age-related hearing loss via the dysregulation of mitochondrial dynamics.
The NLRX1-SLC39A7 complex orchestrates mitochondrial dynamics and mitophagy to rejuvenate intervertebral disc by modulating mitochondrial Zn(2+) trafficking.
DDIT3/CHOP promotes LPS/ATP-induced pyroptosis in osteoblasts via mitophagy inhibition.
The regulatory role of the apelin/APJ axis in scarring: Identification of upstream and downstream mechanisms.
Discovery of 2,8-dihydroxyadenine in HUA patients with uroliths and biomarkers for its associated nephropathy.
LCP1-mediated cytoskeleton alterations involve in arsenite-triggered malignant phenotype of human immortalized prostate stromal cells.
Development of a therapeutic monoclonal antibody against circulating adipocyte fatty acid binding protein to treat ischaemic stroke.
Trilobatin attenuates cerebral ischaemia/reperfusion-induced blood-brain barrier dysfunction by targeting matrix metalloproteinase 9: The legend of a food additive.
Chidamide improves gefitinib treatment outcomes in NSCLC by attenuating recruitment and immunosuppressive function of myeloid-derived suppressor cells.
Iron overload increases the sensitivity of endometriosis stromal cells to ferroptosis via a PRC2-independent function of EZH2.
Design, synthesis, and biological evaluation of gambogenic acid derivatives: Unraveling their anti-cancer effects by inducing pyroptosis.
NF-κB affected the serum levels of TNF-α and IL-1β via activation of the MAPK/NF-κB signaling pathway in rat model of acute pulmonary microthromboembolism.
Nanointegrative Glycoengineering-Activated Necroptosis of Triple Negative Breast Cancer Stem Cells Enables Self-Amplifiable Immunotherapy for Systemic Tumor Rejection.
Xanthohumol ameliorates drug-induced hepatic ferroptosis via activating Nrf2/xCT/GPX4 signaling pathway.
Preparation and characterisation of baicalin magnesium and its protective effect in ulcerative colitis via gut microbiota-bile acid axis modulation.
Tiliroside attenuates acute kidney injury by inhibiting ferroptosis through the disruption of NRF2-KEAP1 interaction.
Cadmium disrupts spermatogenic cell cycle via piRNA-DQ717867/p53 pathway.
Histone deacetylase 6 suppression of renal tubular epithelial cell promotes interstitial mineral deposition via alpha-tubulin acetylation.
Beta-Cell Tipe1 Orchestrates Insulin Secretion and Cell Proliferation by Promoting Gαs/cAMP Signaling via USP5.
Baicalin inhibits monosodium urate crystal-induced pyroptosis in renal tubular epithelial cell line through Panx-1/P2X7 pathways: Molecular docking, molecular dynamics, and in vitro experiments.
PPARγ alleviates preeclampsia development by regulating lipid metabolism and ferroptosis.
Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8(+) T cell effector functions.
Occludin and collagen IV degradation mediated by the T9SS effector SspA contributes to blood-brain barrier damage in ducks during Riemerella anatipestifer infection.
Hesperidin ameliorates H(2)O(2)-induced bovine mammary epithelial cell oxidative stress via the Nrf2 signaling pathway.
LDL receptor-related protein 5 selectively transports unesterified polyunsaturated fatty acids to intracellular compartments.
Activation of the IKK2/NF-κB pathway in VSMCs inhibits calcified vascular stiffness in CKD.
MiR-574-5p activates human TLR8 to promote autoimmune signaling and lupus.
NBR1-p62-Nrf2 mediates the anti-pulmonary fibrosis effects of protodioscin.
ATP Citrate Lyase is a General Tumour Biomarker and Contributes to the Development of Cutaneous Squamous Cell Carcinoma.
Mulberry (Morus alba L.) leaf water extract attenuates type 2 diabetes mellitus by regulating gut microbiota dysbiosis, lipopolysaccharide elevation and endocannabinoid system disorder.
Jiawei Buzhong Yiqi decoction ameliorates polycystic ovary syndrome via oocyte-granulosa cell communication.
Systematic HOIP interactome profiling reveals critical roles of linear ubiquitination in tissue homeostasis.
The role of mTORC1/TFEB axis mediated lysosomal biogenesis and autophagy impairment in fluoride neurotoxicity and the intervention effects of resveratrol.
Identification of HK3 as a promising immunomodulatory and prognostic target in sepsis-induced acute lung injury.
Mycobacterium tuberculosis PE_PGRS38 Enhances Intracellular Survival of Mycobacteria by Inhibiting TLR4/NF-κB-Dependent Inflammation and Apoptosis of the Host.
E2F-mediated POLA2 upregulation is correlated with macrophage infiltration and poor prognosis in hepatocellular carcinoma.
Baicalin reduces inflammation to inhibit lung cancer via targeting SOCS1/NF-κB/STAT3 axis.
Epigenetic regulation of FOXI2 promotes clear cell renal cell carcinoma progression.
Phthalates Induce Neurotoxicity by Disrupting the Mfn2-PERK Axis-Mediated Endoplasmic Reticulum-Mitochondria Interaction.
Expression of Multicopy Tandem Recombinant Ginseng Hexapeptide in Bacillus subtilis and the Evaluation of Antiaging Activity.
Rapamycin alleviates irradiation-induced parotid injury by enhancing the whole gland homeostasis.
CD63(+) cancer-associated fibroblasts confer CDK4/6 inhibitor resistance to breast cancer cells by exosomal miR-20.
Proteomics Identifies LUC7L3 as a Prognostic Biomarker for Hepatocellular Carcinoma.
Agomirs upregulating carboxypeptidase E expression rescue hippocampal neurogenesis and memory deficits in Alzheimer's disease.
Sphingolipid biosynthesis is essential for metabolic rewiring during T(H)17 cell differentiation.
Expression and functional significance of phosphoenolpyruvate carboxykinase 1 in uveal melanoma.
Peptide Inhibitor Targeting the Extraterminal Domain in BRD4 Potently Suppresses Breast Cancer Both In Vitro and In Vivo.
Structure-Guided Discovery and Preclinical Assessment of Novel (Thiophen-3-yl)aminopyrimidine Derivatives as Potent ERK1/2 Inhibitors.
Pterostilbene nanoemulsion promotes Nrf2 signaling pathway to downregulate oxidative stress for treating Alzheimer's disease.
Abrogation of KLF5 sensitizes BRCA1-proficient pancreatic cancer to PARP inhibition.
Norcantharidin Enhances the Antitumor Effect of 5-Fluorouracil by Inducing Apoptosis of Cervical Cancer Cells: Network Pharmacology, Molecular Docking, and Experimental Validation.
Association of Cadherin-Related Family Member 1 with Traumatic Brain Injury.
Anti-hepatocellular carcinoma activity of Sorbaria sorbifolia by regulating VEGFR and c-Met/apoptotic pathway.
Leech extract alleviates idiopathic pulmonary fibrosis by TGF-β1/Smad3 signaling pathway.
Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome.
Genetic or pharmacologic blockade of mPGES-2 attenuates renal lipotoxicity and diabetic kidney disease by targeting Rev-Erbα/FABP5 signaling.
Hippo-signaling-controlled MHC class I antigen processing and presentation pathway potentiates antitumor immunity.
Systematic optimization and evaluation of culture conditions for the construction of circulating tumor cell clusters using breast cancer cell lines.
PCV2 Induced Endothelial Derived IL-8 Affects MoDCs Maturation Mainly via NF-κB Signaling Pathway.
Caspase-1 Deficiency Modulates Adipogenesis through Atg7-Mediated Autophagy: An Inflammatory-Independent Mechanism.
Ascorbyl palmitate ameliorates inflammatory diseases by inhibition of NLRP3 inflammasome.
The prevention effect of pulsed electromagnetic fields treatment on senile osteoporosis in vivo via improving the inflammatory bone microenvironment.
TRAF6-mediated ubiquitination of AKT in the nucleus is a critical event underlying the desensitization of G protein-coupled receptors.
Profiling the role of m6A effectors in the regulation of pluripotent reprogramming.
miR-3188 inhibits hepatitis B virus transcription by targeting Bcl-2.
Macrophage-derived exosomes rescue the TNF-ɑ-suppressed osteo-/cementogenic differentiation of hPDLCs.
Dimethyl fumarate covalently modifies Cys673 of NLRP3 to exert anti-inflammatory effects.
TDP-43 deficiency in suprachiasmatic nucleus perturbs rhythmicity of neuroactivity in prefrontal cortex.
The deubiquitinase cofactor UAF1 interacts with USP1 and plays an essential role in spermiogenesis.
Insulin-like growth factor-1 promotes the testicular sperm production by improving germ cell survival and proliferation in high-fat diet-treated male mice.
Neutrophil Extracellular Traps Regulate Surgical Brain Injury by Activating the cGAS-STING Pathway.
Verapamil Attenuates the Severity of Tendinopathy by Mitigating Mitochondrial Dysfunction through the Activation of the Nrf2/HO-1 Pathway.
Resveratrol Alleviates Zearalenone-Induced Intestinal Dysfunction in Mice through the NF-κB/Nrf2/HO-1 Signalling Pathway.
KDM5C-Mediated Recruitment of BRD4 to Chromatin Regulates Enhancer Activation and BET Inhibitor Sensitivity.
Association of GAL-8 promoter methylation levels with coronary plaque inflammation.
Human umbilical cord mesenchymal stem cell-derived exosomes ameliorate renal fibrosis in diabetic nephropathy by targeting Hedgehog/SMO signaling.
PRMT4 interacts with NCOA4 to inhibit ferritinophagy in cisplatin-induced acute kidney injury.
Integrated network toxicology, molecular docking, and in vivo experiments to elucidate molecular mechanism of aflatoxin B1 hepatotoxicity.
Quinic acid regulated TMA/TMAO-related lipid metabolism and vascular endothelial function through gut microbiota to inhibit atherosclerotic.
zDHHC3-mediated S-palmitoylation of SLC9A2 regulates apoptosis in kidney clear cell carcinoma.
Taurine ameliorates sensorimotor function by inhibiting apoptosis and activating A2 astrocytes in mice after subarachnoid hemorrhage.
CCDC58 is a potential biomarker for diagnosis, prognosis, immunity, and genomic heterogeneity in pan-cancer.
Functional analysis and validation of oncodrive gene AP3S1 in ovarian cancer through filtering of mutation data from whole-exome sequencing.
Hawthorn Proanthocyanidin Extract Inhibits Colorectal Carcinoma Metastasis by Targeting the Epithelial-Mesenchymal Transition Process and Wnt/β-Catenin Signaling Pathway.
Hazel Leaf Polyphenol Extract Alleviated Cisplatin-Induced Acute Kidney Injury by Reducing Ferroptosis through Inhibiting Hippo Signaling.
Unlocking the Therapeutic Potential of a Manila Clam-Derived Antioxidant Peptide: Insights into Mechanisms of Action and Cytoprotective Effects against Oxidative Stress.
Targeting FTO induces colorectal cancer ferroptotic cell death by decreasing SLC7A11/GPX4 expression.
The W195 Residue of the Newcastle Disease Virus V Protein Is Critical for Multiple Aspects of Viral Self-Regulation through Interactions between V and Nucleoproteins.
Protective Effects of Isoliquiritigenin and Licochalcone B on the Immunotoxicity of BDE-47: Antioxidant Effects Based on the Activation of the Nrf2 Pathway and Inhibition of the NF-κB Pathway.
Hepatic LGR4 aggravates cholestasis-induced liver injury in mice.
Rutin mitigates fluoride-induced nephrotoxicity by inhibiting ROS-mediated lysosomal membrane permeabilization and the GSDME-HMGB1 axis involved in pyroptosis and inflammation.
Mechanically tough, adhesive, self-healing hydrogel promotes annulus fibrosus repair via autologous cell recruitment and microenvironment regulation.
Caged xanthone derivatives to promote mitochondria-mediated apoptosis in breast cancer cells.
MiR-181c-5p ameliorates learning and memory in sleep-deprived mice via HMGB1/TLR4/NF-κB pathway.
The Involvement of PGRMC1 Signaling in Cognitive Impairment Induced by Long-Term Clozapine Treatment in Rats.
Semisynthesis and in Vitro Anti-cancer Effect of New Magnolol Derivatives on the Cell Proliferation, Apoptosis, Migration, and Invasion of Human Hepatocellular Carcinoma SMMC-7721 Cells.
NRF1 Alleviated Oxidative Stress of Glioblastoma Cells by Regulating NOR1.
FNDC5 Attenuates Atherosclerotic Plaque Formation and Regulates PPARα/HO-1 in ApoE-/- Mice.
CDKs Functional Analysis in Low Proliferating Early-Stage Pancreatic Ductal Adenocarcinoma.
Phenolic profile, antioxidation and anti-proliferation activity of phenolic-rich extracts from Sanghuangporusvaninii.
Baicalin Ameliorates Lung Injury in Rats by Inhibiting NLRP3 Inflammasome Activation via NF-[Formula: see text]B Signaling Pathway.
Amelioration of Lung Fibrosis by Total Flavonoids of Astragalus via Inflammatory Modulation and Epithelium Regeneration.
Baicalin Reduces Immune Cell Infiltration by Inhibiting Inflammation and Protecting Tight Junctions in Ischemic Stroke Injury.
Propofol improves ischemia reperfusion-induced liver fibrosis by regulating lncRNA HOXA11-AS.
Methylthioacetic acid, a derivative of aroma compounds from Cucumis melo var. conomon dose-dependently triggers differentiation and apoptosis of RCM-1 human colorectal cancer cells.
ESE-1 mediates lipopolysaccharide-induced BV2 cell inflammation via upregulation of HMGB1 expression.
Ponicidin Induces Apoptosis of Murine Melanoma by Inhibiting the NF-κB Signaling Pathway.
C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways.
Exploring the Targets and Molecular Mechanisms of Thalidomide in the Treatment of Ulcerative Colitis: Network Pharmacology and Experimental Validation.
Lycium barbarum Polysaccharides Regulating miR-181/Bcl-2 Decreased Autophagy of Retinal Pigment Epithelium with Oxidative Stress.
STK24 Promotes Progression of LUAD and Modulates the Immune Microenvironment.
Pterostilbene Confers Protection against Diquat-Induced Intestinal Damage with Potential Regulation of Redox Status and Ferroptosis in Broiler Chickens.
Exploring the Effect of Compound Glycyrrhizin and Silybinin on the Metabolism of Pexidartinib in Rats Based on CYP3A4 and CYP2C9.
JFD, a Novel Natural Inhibitor of Keap1 Alkylation, Suppresses Intracellular Mycobacterium Tuberculosis Growth through Keap1/Nrf2/SOD2-Mediated ROS Accumulation.
Xuanhuang Runtong Tablets Relieve Slow Transit Constipation in Mice by Regulating TLR5/IL-17A Signaling Mediated by Gut Microbes.
Network Pharmacology-Based Identification of Key Targets of Ziyin Mingmu Pills Acting on Age-Related Macular Degeneration.
Inhibition of miR-182-5p Targets FGF9 to Alleviate Osteoarthritis.
Human Umbilical Cord Mesenchymal Stem Cells Inhibit Pyroptosis of Renal Tubular Epithelial Cells through miR-342-3p/Caspase1 Signaling Pathway in Diabetic Nephropathy.
Vasoprotective Effects of Hyperoside against Cerebral Ischemia/Reperfusion Injury in Rats: Activation of Large-Conductance Ca(2+)-Activated K(+) Channels.
The Interaction of Apelin and FGFR1 Ameliorated the Kidney Fibrosis through Suppression of TGFβ-Induced Endothelial-to-Mesenchymal Transition.
QiHuangYiShen Granules Modulate the Expression of LncRNA MALAT1 and Attenuate Epithelial-Mesenchymal Transition in Kidney of Diabetic Nephropathy Rats.
Calpain-2 Facilitates Autophagic/Lysosomal Defects and Apoptosis in ARPE-19 Cells and Rats Induced by Exosomes from RPE Cells under NaIO(3) Stimulation.
Upregulation of NDUFAF2 in Lung Adenocarcinoma Is a Novel Independent Prognostic Biomarker.
Microbiota from Exercise Mice Counteracts High-Fat High-Cholesterol Diet-Induced Cognitive Impairment in C57BL/6 Mice.
Characterization of TIM-3 Expression and Its Correlation with TNF-α and IFN-γ in Patients with Surgically Resected Lung Adenocarcinoma.
Prevention of Bleomycin-Induced Pulmonary Inflammation and Fibrosis in Mice by Bilobalide.
Leonurine Regulates Hippocampal Nerve Regeneration in Rats with Chronic and Unpredictable Mild Stress by Activating SHH/GLI Signaling Pathway and Restoring Gut Microbiota and Microbial Metabolic Homeostasis.
Traxoprodil Produces Antidepressant-Like Behaviors in Chronic Unpredictable Mild Stress Mice through BDNF/ERK/CREB and AKT/FOXO/Bim Signaling Pathway.
Anomanolide C suppresses tumor progression and metastasis by ubiquitinating GPX4-driven autophagy-dependent ferroptosis in triple negative breast cancer.
Berberine inhibits high fat diet-associated colorectal cancer through modulation of the gut microbiota-mediated lysophosphatidylcholine.
NLRP3 Inflammasome Mediates Silica-induced Lung Epithelial Injury and Aberrant Regeneration in Lung Stem/Progenitor Cell-derived Organotypic Models.
M6A-modified circRBM33 promotes prostate cancer progression via PDHA1-mediated mitochondrial respiration regulation and presents a potential target for ARSI therapy.
Development and anticancer properties of Up284, a spirocyclic candidate ADRM1/RPN13 inhibitor.
Combinatorial expression of ebony and tan generates body color variation from nymph through adult stages in the cricket, Gryllus bimaculatus.
Mitochondrial decline in the ageing old world primate retina: Little evidence for difference between the centre and periphery.
Downregulation of KIAA1199 alleviated the activation, proliferation, and migration of hepatic stellate cells by the inhibition of epithelial-mesenchymal transition.
Identification and Characterization of a Novel Nanobody Against Human CTGF to Reveal Its Antifibrotic Effect in an in vitro Model of Liver Fibrosis.
Glycosylation-Engineered Platelet Membrane-Coated Interleukin 10 Nanoparticles for Targeted Inhibition of Vascular Restenosis.
Integrated Network Pharmacology, Molecular Docking and Animal Experiment to Explore the Efficacy and Potential Mechanism of Baiyu Decoction Against Ulcerative Colitis by Enema.
Jiawei Danxuan Koukang Alleviates Arecoline Induced Oral Mucosal Lesions: Network Pharmacology and the Combined Ultra-High Performance Liquid Chromatography (UPLC) and Mass Spectrometry (MS).
10-Gingerol Enhances the Effect of Taxol in Triple-Negative Breast Cancer via Targeting ADRB2 Signaling.
K(+)/Cl(-) cotransporter 2 (KCC2) and Na(+)/HCO3- cotransporter 1 (NBCe1) interaction modulates profile of KCC2 phosphorylation.
EFEMP1 is a potential biomarker of choroid thickness change in myopia.
Network pharmacology reveals that Berberine may function against Alzheimer's disease via the AKT signaling pathway.
Semaphorin4F is a potential biomarker for clinical progression and prognosis in gastric cancer.
Establishment of Risk Model and Analysis of Immunoinfiltration Based on Mitophagy-Related Associated Genes in Atrial Fibrillation.
Comprehensive Analysis of NABP2 as a Prognostic Biomarker and Its Correlation with Immune Infiltration in Hepatocellular Carcinoma.
Integrated proteomics and metabolomics analysis of D-pinitol function during hippocampal damage in streptozocin-induced aging-accelerated mice.
Sex Differences in Genomic Features of Hepatitis B-Associated Hepatocellular Carcinoma With Distinct Antitumor Immunity.
HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.
CKIP-1 mediates P. gingivalis-suppressed osteogenic/cementogenic differentiation of periodontal ligament cells partially via p38 signaling pathway.
Slc6a13 Deficiency Attenuates Pasteurella multocida Infection-Induced Inflammation via Glycine-Inflammasome Signaling.
PIWI-interacting RNA-17458 is oncogenic and a potential therapeutic target in cervical cancer.
A Positive Feedback Loop of E2F4-Mediated Activation of MNX1 Regulates Tumour Progression in Colorectal Cancer.
ALDOB plays a tumor-suppressive role by inhibiting AKT activation in gastric cancer.
Up-regulation of ABCG1 is associated with methotrexate resistance in acute lymphoblastic leukemia cells.
Integration of RRBS and RNA-seq unravels the regulatory role of DNMT3A in porcine Sertoli cell proliferation.
Secondary metabolites of Bacillus subtilis L2 show antiviral activity against pseudorabies virus.
Direct interaction of the molecular chaperone GRP78/BiP with the Newcastle disease virus hemagglutinin-neuraminidase protein plays a vital role in viral attachment to and infection of culture cells.
Tangeretin attenuates bleomycin-induced pulmonary fibrosis by inhibiting epithelial-mesenchymal transition via the PI3K/Akt pathway.
6-Gingerol alleviates placental injury in preeclampsia by inhibiting oxidative stress via BNIP3/LC3 signaling-mediated trophoblast mitophagy.
Transcriptome sequencing and functional verification revealed the roles of exogenous magnesium in tobacco anti-PVY infection.
Artesunate, as an Hsp90 inhibitor, inhibits the proliferation of Burkitt's lymphoma cells by inhibiting AKT and ERK.
Choroidal circulation disturbance is an initial factor in outer retinal degeneration in rats under simulated weightlessness.
Electroacupuncture alleviates ulcerative colitis by targeting CXCL1: evidence from the transcriptome and validation.
Cholesterol 25-hydroxylase suppresses avian reovirus replication by its enzymatic product 25-hydroxycholesterol.
Acute murine cytomegalovirus infection boosts cell-type specific response and lipid metabolism changes in the liver of infant mice.
African swine fever virus pA104R protein acts as a suppressor of type I interferon signaling.
Role of asparagine biosynthesis pathway in Siniperca chuatsi rhabdovirus proliferation.
Probiotics treatment ameliorated mycophenolic acid-induced colitis by enhancing intestinal barrier function and improving intestinal microbiota dysbiosis in mice.
Tetrandrine inhibits the proliferation of mesangial cells induced by enzymatically deglycosylated human IgA1 via IgA receptor/MAPK/NF-κB signaling pathway.
Gut microbiota from sigma-1 receptor knockout mice induces depression-like behaviors and modulates the cAMP/CREB/BDNF signaling pathway.
E. coli Nissle 1917 ameliorates mitochondrial injury of granulosa cells in polycystic ovary syndrome through promoting gut immune factor IL-22 via gut microbiota and microbial metabolism.
Apilimod activates the NLRP3 inflammasome through lysosome-mediated mitochondrial damage.
Identification and validation of hub genes in drug induced acute kidney injury basing on integrated transcriptomic analysis.
Protective effects of Scutellariae Radix Carbonisata-derived carbon dots on blood-heat and hemorrhage rats.
TIGAR deficiency induces caspase-1-dependent trophoblasts pyroptosis through NLRP3-ASC inflammasome.
Dendrobium mixture ameliorates type 2 diabetes mellitus with non-alcoholic fatty liver disease through PPAR gamma: An integrated study of bioinformatics analysis and experimental verification.
Effect of acupuncture on the opening time of implantation window and endometrial receptivity in controlled ovarian hyperstimulation rats during peri-implantation period.
Dietary fiber alters immunity and intestinal barrier function of different breeds of growing pigs.
The TRPM4 channel inhibitor 9-phenanthrol alleviates cerebral edema after traumatic brain injury in rats.
Sirtuin 1 activator alleviated lethal inflammatory injury via promotion of autophagic degradation of pyruvate kinase M2.
Identification of immune signatures in Parkinson's disease based on co-expression networks.
RUNX1/CD44 axis regulates the proliferation, migration, and immunotherapy of gliomas: A single-cell sequencing analysis.
Integrated analysis of Dendrobium nobile extract Dendrobin A against pancreatic ductal adenocarcinoma based on network pharmacology, bioinformatics, and validation experiments.
The prognostic value of the GPAT/AGPAT gene family in hepatocellular carcinoma and its role in the tumor immune microenvironment.
A strategy of local hydrogen capture and catalytic hydrogenation for enhanced therapy of chronic liver diseases.
Platelets promote CRC by activating the C5a/C5aR1 axis via PSGL-1/JNK/STAT1 signaling in tumor-associated macrophages.
ZY-444 inhibits the growth and metastasis of prostate cancer by targeting TNFAIP3 through TNF signaling pathway.
IRG1/Itaconate induces metabolic reprogramming to suppress ER-positive breast cancer cell growth.
DNMT1 mediates the disturbed flow-induced endothelial to mesenchymal transition through disrupting β-alanine and carnosine homeostasis.
Network pharmacology and experimental verification reveal the mechanism of safranal against glioblastoma (GBM).
BPOZ-2 is a negative regulator of the NLPR3 inflammasome contributing to SARS-CoV-2-induced hyperinflammation.
Study on the protective effect of OM-MSCs on Golgi apparatus after intracerebral hemorrhage in Sprague-Dawley rats.
Selective HDAC6 inhibitor TubA offers neuroprotection after intracerebral hemorrhage via inhibiting neuronal apoptosis.
Investigation of anti-diabetic effect of a novel coenzyme Q10 derivative.
Tanshinone IIA inhibits cardiomyocyte pyroptosis through TLR4/NF-κB p65 pathway after acute myocardial infarction.
Evidence for developmental vascular-associated necroptosis and its contribution to venous-lymphatic endothelial differentiation.
Role of UDP-glucose ceramide glucosyltransferase in venous malformation.
The combination of NDUFS1 with CD4(+) T cell infiltration predicts favorable prognosis in kidney renal clear cell carcinoma.
Effect of blood flow-restricted resistance training on myocardial fibrosis in early spontaneously hypertensive rats.
Inhibition of tiRNA-Gly-GCC ameliorates neointimal formation via CBX3-mediated VSMCs phenotypic switching.
Role of NLRP3 inflammasome activation in HCC cell progression.
Electroacupuncture preconditioning protects against myocardial ischemia-reperfusion injury by modulating dynamic inflammatory response.
MAVI1, an endoplasmic reticulum-localized microprotein, suppresses antiviral innate immune response by targeting MAVS on mitochondrion.
WBP2 restrains the lysosomal degradation of GPX4 to inhibit ferroptosis in cisplatin-induced acute kidney injury.
Transcription Factor BCL11A Regulates Schwann Cell Behavior During Peripheral Nerve Regeneration.
Moderate Intensity of Treadmill Exercise Rescues TBI-Induced Ferroptosis, Neurodegeneration, and Cognitive Impairments via Suppressing STING Pathway.
TRIM9 promotes Müller cell-derived retinal stem cells to differentiate into retinal ganglion cells by regulating Atoh7.
Isoquercitrin Played a Neuroprotective Role in Rats After Cerebral Ischemia/Reperfusion Through Up-Regulating Neuroglobin and Anti-Oxidative Stress.
Hypoxia caused by unilateral nasal obstruction decreases mandibular density in rats through inhibition of Cyp1a1 expression.
Sophoricoside attenuates autoimmune‑mediated liver injury through the regulation of oxidative stress and the NF‑κB signaling pathway.
FBXO28 suppresses liver cancer invasion and metastasis by promoting PKA-dependent SNAI2 degradation.
Klotho-beta attenuates Rab8a-mediated exosome regulation and promotes prostate cancer progression.
The Circadian System Is Essential for the Crosstalk of VEGF-Notch-mediated Endothelial Angiogenesis in Ischemic Stroke.
Cuproptosis enhances docetaxel chemosensitivity by inhibiting autophagy via the DLAT/mTOR pathway in prostate cancer.
Pinocembrin alleviates pyroptosis and apoptosis through ROS elimination in random skin flaps via activation of SIRT3.
Isoamericanin A improves lipopolysaccharide-induced memory impairment in mice through suppression of the nicotinamide adenine dinucleotide phosphateoxidase-dependent nuclear factor kappa B signaling pathway.
LINC00938 alleviates hypoxia ischemia encephalopathy induced neonatal brain injury by regulating oxidative stress and inhibiting JNK/p38 MAPK signaling pathway.
Silibinin ameliorates deoxycholic acid-induced pyroptosis in steatotic HepG2 cells by inhibiting NLRP3 inflammasome activation.
CHAF1A promotes the proliferation and growth of epithelial ovarian cancer cells by affecting the phosphorylation of JAK2/STAT3 signaling pathway.
Lysine methylation of PPP1CA by the methyltransferase SUV39H2 disrupts TFEB-dependent autophagy and promotes intervertebral disc degeneration.
Porcine reproductive and respiratory syndrome virus-mediated lactate facilitates virus replication by targeting MAVS.
PEDV N protein capture protein translation element PABPC1 and eIF4F to promote viral replication.
PRRSV inhibited the proliferation of CSFV by inducing IL-1β maturation via NLRP3 inflammasome activation.
Tetracaine hydrochloride induces macrophage pyroptosis through caspase‑1/11‑GSDMD signaling pathways.
Antisense lncRNA-RP11-498C9.13 promotes bladder cancer progression by enhancing reactive oxygen species-induced mitophagy.
Knockdown of AK142426 suppresses M2 macrophage polarization and inflammation in peritoneal fibrosis via binding to c-Jun.
Whether the Subacute MPTP-Treated Mouse is as Suitable as a Classic Model of Parkinsonism.
Glutaredoxin 2 protects lens epithelial cells from epithelial-mesenchymal transition by suppressing mitochondrial oxidative stress-related upregulation of integrin-linked kinase.
The long noncoding RNA CIRBIL is a regulator of steroidogenesis in mice.
EIF4A3-regulated hsa_circ_0001445 can inhibit the progression of laryngeal squamous cell carcinoma via hsa-miR-432-5p-dependent up-regulation of RGMA expression.
Hypoxia-induced GPCPD1 depalmitoylation triggers mitophagy via regulating PRKN-mediated ubiquitination of VDAC1.
Heat shock factor 1 promotes neurite outgrowth and suppresses inflammation in the severed spinal cord of geckos.
TRAF6-TAK1-IKKβ pathway mediates TLR2 agonists activating "one-step" NLRP3 inflammasome in human monocytes.
The 5-HT(7) receptors in the VLO contribute to the development of morphine-induced behavioral sensitization in rats.
Analysis of gene expression profiles and experimental validations of a rat chronic cervical cord compression model.
The mechanism of metformin combined with total flavonoids of Rhizoma Drynariae on ovariectomy-induced osteoporotic rats.
PFKFB2 is a favorable prognostic biomarker for colorectal cancer by suppressing metastasis and tumor glycolysis.
USP2 promotes cell proliferation and metastasis in choroidal melanoma via stabilizing Snail.
In vitro and in vivo study on the treatment of non-small cell lung cancer with radionuclide labeled PD-L1 nanobody.
The kinase inhibitory region of SOCS3 attenuates reactive astrogliosis and astroglial scar in mice after traumatic brain injury.
IGF2BP3 mediates the mRNA degradation of NF1 to promote triple-negative breast cancer progression via an m6A-dependent manner.
Circular RNA circARPC1B functions as a stabilisation enhancer of Vimentin to prevent high cholesterol-induced articular cartilage degeneration.
ACSL4 promotes ferroptosis and M1 macrophage polarization to regulate the tumorigenesis of nasopharyngeal carcinoma.
Pharmacological activation of the Nrf2 pathway by Taxifolin remodels articular cartilage microenvironment for the therapy of Osteoarthritis.
CD73 inhibits titanium particle-associated aseptic loosening by alternating activation of macrophages.
Lunasin reduces the susceptibility of IL-10 deficient mice to inflammatory bowel disease and modulates the activation of the NLRP3 inflammasome.
Comparison of endocytosis pathways of Duck Tembusu virus in BHK-21 and duck embryo fibroblasts.
miR-146b-5p promotes duck Tembusu virus replication by targeting RPS14.
Targeted knockout of Mx in the DF-1 chicken fibroblast cell line impairs immune response against Newcastle disease virus.
TP53RK Drives the Progression of Chronic Kidney Disease by Phosphorylating Birc5.
Estrogen-Induced LncRNA, LINC02568, Promotes Estrogen Receptor-Positive Breast Cancer Development and Drug Resistance Through Both In Trans and In Cis Mechanisms.
Ochratoxin A induces abnormal tryptophan metabolism in the intestine and liver to activate AMPK signaling pathway.
Gut microbes exacerbate systemic inflammation and behavior disorders in neurologic disease CADASIL.
Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation.
SUMO1-regulated DBC1 promotes p53-dependent stress-induced apoptosis of lens epithelial cells.
Asarinin attenuates bleomycin-induced pulmonary fibrosis by activating PPARγ.
Reduced expression of phosphorylated ataxia-telangiectasia mutated gene is related to poor prognosis and gemcitabine chemoresistance in pancreatic cancer.
A novel small molecule effectively ameliorates estrogen deficiency-induced osteoporosis by targeting the gut-bone signaling axis.
1,8-Cineole ameliorates endothelial injury and hypertension induced by L-NAME through regulation of autophagy via PI3K/mTOR signaling pathway.
Activation of TrkB signaling mitigates cerebellar anomalies caused by Rbm4-Bdnf deficiency.
Structural characterization of human RPA70N association with DNA damage response proteins.
A twin UGUA motif directs the balance between gene isoforms through CFIm and the mTORC1 signaling pathway.
Preparation of a new resource food-arabinogalactan and its protective effect against enterotoxicity in IEC-6 cells by inhibiting endoplasmic reticulum stress.
A multifunctional polydopamine/genipin/alendronate nanoparticle licences fibrin hydrogels osteoinductive and immunomodulatory potencies for repairing bone defects.
miR-491-5p regulates the susceptibility of glioblastoma to ferroptosis through TP53.
Hesperidin inhibits methylation and autophagy in LPS and high glucose-induced human villous trophoblasts.
Gastrodin relieves cognitive impairment by regulating autophagy via PI3K/AKT signaling pathway in vascular dementia.
Antidiabetic Effect of Collagen Peptides from Harpadon nehereus Bones in Streptozotocin-Induced Diabetes Mice by Regulating Oxidative Stress and Glucose Metabolism.
HSP90B1-mediated plasma membrane localization of GLUT1 promotes radioresistance of glioblastomas.
The Gut Microbiota of Pregnant Rats Alleviates Fetal Growth Restriction by Inhibiting the TLR9/MyD88 Pathway.
Benzophenanthridine Alkaloid Chelerythrine Elicits Necroptosis of Gastric Cancer Cells via Selective Conjugation at the Redox Hyperreactive C-Terminal Sec(498) Residue of Cytosolic Selenoprotein Thioredoxin Reductase.
PUF60 promotes cell cycle and lung cancer progression by regulating alternative splicing of CDC25C.
PM2.5 leads to adverse pregnancy outcomes by inducing trophoblast oxidative stress and mitochondrial apoptosis via KLF9/CYP1A1 transcriptional axis.
TSWIFT, a novel method for iterative staining of embedded and mounted human brain sections.
Glucose Starvation Stimulates the Promoting Strength of a Novel Evolved Suc2 Promoter.
[miRNA-128-3p inhibits malignant behavior of glioma cells by downregulating KLHDC8A expression].
A Unique G-Quadruplex Aptamer: A Novel Approach for Cancer Cell Recognition, Cell Membrane Visualization, and RSV Infection Detection.
Icariin-Curcumol promotes docetaxel sensitivity in prostate cancer through modulation of the PI3K-Akt signaling pathway and the Warburg effect.
Lactobacillus fermentum Alleviates the Colorectal Inflammation Induced by Low-Dose Sub-Chronic Microcystin-LR Exposure.
Long-Term Exposure to Microcystin-LR Induces Gastric Toxicity by Activating the Mitogen-Activated Protein Kinase Signaling Pathway.
Rosmarinic acid ameliorates autoimmune responses through suppression of intracellular nucleic acid-mediated type I interferon expression.
Specific inhibitory effects of guanosine on breast cancer cell proliferation.
Hypoxic Preconditioning Enhances Cellular Viability and Migratory Ability: Role of DANCR/miR-656-3p/HIF-1α Axis in Placental Mesenchymal Stem Cells.
Ginsenoside Rg1 attenuates diabetic vascular endothelial dysfunction by inhibiting the calpain-1/ROS/PKC-β axis.
Modified Gegen Qinlian decoction ameliorated ulcerative colitis by attenuating inflammation and oxidative stress and enhancing intestinal barrier function in vivo and in vitro.
Congenital cataracts affect the retinal visual cycle and mitochondrial function: A multi-omics study of GJA8 knockout rabbits.
ATG7 upregulation contributes to malignant transformation of human bronchial epithelial cells by B[a]PDE via DNMT3B protein degradation and miR-494 promoter methylation.
Cadmium exposure promotes ferroptosis by upregulating Heat Shock Protein 70 in vascular endothelial damage of zebrafish.
A stepwise and digital pattern of RSK phosphorylation determines the outcome of thymic selection.
Systemic gene therapy using an AAV44.9 vector rescues a neonatal lethal mouse model of propionic acidemia.
Solar ultraviolet B radiation promotes α-MSH secretion to attenuate the function of ILC2s via the pituitary-lung axis.
Oxidative stress mediates hippocampal neuronal apoptosis through ROS/JNK/P53 pathway in rats with PTSD triggered by high-voltage electrical burn.
Codium fragile Suppressed Chronic PM(2.5)-Exposed Pulmonary Dysfunction via TLR/TGF-β Pathway in BALB/c Mice.
Long-term iTBS Improves Neural Functional Recovery by Reducing the Inflammatory Response and Inhibiting Neuronal Apoptosis Via miR-34c-5p/p53/Bax Signaling Pathway in Cerebral Ischemic Rats.
Gambogenic acid induces cell death in human osteosarcoma through altering iron metabolism, disturbing the redox balance, and activating the P53 signaling pathway.
Epithelial TIPE1 Protein Guards against Colitis by Inhibiting TNF-α-Mediated Inflammation.
TGR5 supresses cGAS/STING pathway by inhibiting GRP75-mediated endoplasmic reticulum-mitochondrial coupling in diabetic retinopathy.
DSTN Hypomethylation Promotes Radiotherapy Resistance of Rectal Cancer by Activating the Wnt/β-Catenin Signaling Pathway.
RBM15‑mediating MDR1 mRNA m(6)A methylation regulated by the TGF‑β signaling pathway in paclitaxel‑resistant ovarian cancer.
Ghrelin inhibits NLRP3 inflammasome activation by upregulating autophagy to improve Alzheimer's disease.
Quercetin promotes autophagy to alleviate cigarette smoke-related periodontitis.
Molecular classification of hormone receptor-positive HER2-negative breast cancer.
Fine particulate matter promotes airway inflammation and mucin production by activating endoplasmic reticulum stress and the IRE1α/NOD1/NF‑κB pathway.
Loss of hepatic FTCD promotes lipid accumulation and hepatocarcinogenesis by upregulating PPARγ and SREBP2.
IGF-1 Combined with OPN Promotes Neuronal Axon Growth in Vitro Through the IGF-1R/Akt/mTOR Signaling Pathway in Lipid Rafts.
VCAM-1(+) hUC-MSCs Exert Considerable Neuroprotection Against Cerebral Infarction in Rats by Suppression of NLRP3-Induced Pyroptosis.
Pregnane X receptor activation alleviates renal fibrosis in mice via interacting with p53 and inhibiting the Wnt7a/β-catenin signaling.
miR-188-5p silencing improves cerebral ischemia/reperfusion injury by targeting Lin28a.
The potential mechanism of Choulingdan mixture in improving acute lung injury based on HPLC-Q-TOF-MS, network pharmacology and in vivo experiments.
Bavachinin selectively modulates PPAR γ and maintains bone homeostasis in Type 2 Diabetes.
Paternal cadmium exposure induces glucolipid metabolic reprogramming in offspring mice via PPAR signaling pathway.
BCKDHA contributes to melanoma progression by promoting the expressions of lipogenic enzymes FASN and ACLY.
Filamin A facilitates NLRP3 inflammasome activation during arsenic-induced nonalcoholic steatohepatitis.
The E3 ubiquitin ligase TRIM17 promotes gastric cancer survival and progression via controlling BAX stability and antagonizing apoptosis.
LncRNA BCAN-AS1 stabilizes c-Myc via N(6)-methyladenosine-mediated binding with SNIP1 to promote pancreatic cancer.
DJ-1-mediated p62 degradation delays intervertebral disc degeneration by inhibiting apoptosis of nucleus pulposus cells.
Oncogenic roles of GPR176 in breast cancer: a potential marker of aggressiveness and a potential target of gene therapy.
CRISPR/SaCas9-based gene editing rescues photoreceptor degeneration throughout a rhodopsin-associated autosomal dominant retinitis pigmentosa mouse model.
Functional analysis of two abnormal antithrombin proteins with different intracellular kinetics.
ACLY promotes gastric tumorigenesis and accelerates peritoneal metastasis of gastric cancer regulated by HIF-1A.
IGF2BP2 promotes glycolysis and hepatocellular carcinoma stemness by stabilizing CDC45 mRNA via m6A modification.
EGFR suppression contributes to growth inhibitory activity of G-quadruplex ligands in non-small cell lung cancers.
Histone methyltransferase SETD2 inhibits M1 macrophage polarization and glycolysis by suppressing HIF-1α in sepsis-induced acute lung injury.
FN1 mediated activation of aspartate metabolism promotes the progression of triple-negative and luminal a breast cancer.
A sequential scheme including PTT and 2'3'-cGAMP/CQ-LP reveals the antitumor immune function of PTT through the type I interferon pathway.
Ampelopsin attenuates Staphylococcus aureus Alpha-Toxin-Induced Lung Injury.
Activation of Nrf2 signalling pathway by tectoridin protects against ferroptosis in particulate matter-induced lung injury.
6-Mercaptopurine potently inhibits recruitment of SHP2 by phosphorylated PD-1 to inhibit PD-1 signalling and enhance T cell function.
The role of the gut-microbiota-brain axis via the subdiaphragmatic vagus nerve in chronic inflammatory pain and comorbid spatial working memory impairment in complete Freund's adjuvant mice.
Babao Dan alleviates gut immune and microbiota disorders while impacting the TLR4/MyD88/NF-кB pathway to attenuate 5-Fluorouracil-induced intestinal injury.
Undesirable ER stress induced by bavachin contributed to follicular atresia in zebrafish ovary.
Synthesis and biological evaluation of chromanone-based derivatives as potential anti-neuroinflammatory agents.
Cullin-associated and neddylation-dissociated 1 regulate reprogramming of lipid metabolism through SKP1-Cullin-1-F-box(FBXO11) -mediated heterogeneous nuclear ribonucleoprotein A2/B1 ubiquitination and promote hepatocellular carcinoma.
Quercetin ameliorates nonalcoholic fatty liver disease (NAFLD) via the promotion of AMPK-mediated hepatic mitophagy.
Anti-rheumatoid arthritis effects of total saponins from Rhizoma Panacis Majoris on adjuvant-induced arthritis in rats and rheumatoid arthritis fibroblast-like synoviocytes.
OTUB1's role in promoting OSCC development by stabilizing RACK1 involves cell proliferation, migration, invasion, and tumor-associated macrophage M1 polarization.
Puerarin protects against acetaminophen-induced oxidative damage in liver through activation of the Keap1/Nrf2 signaling pathway.
CCDC50 promotes tumor growth through regulation of lysosome homeostasis.
URI alleviates tyrosine kinase inhibitors-induced ferroptosis by reprogramming lipid metabolism in p53 wild-type liver cancers.
PI3K/mTOR inhibitors promote G6PD autophagic degradation and exacerbate oxidative stress damage to radiosensitize small cell lung cancer.
Prefrontal cortex-specific Dcc deletion induces schizophrenia-related behavioral phenotypes and fail to be rescued by olanzapine treatment.
C1632 inhibits ovarian cancer cell growth and migration by inhibiting LIN28 B/let-7/FAK signaling pathway and FAK phosphorylation.
VPS41-mediated incomplete autophagy aggravates cadmium-induced apoptosis in mouse hepatocytes.
Inhibition of adult hippocampal neurogenesis induced by postoperative CD8 + T-cell infiltration is associated with cognitive decline later following surgery in adult mice.
STING/ACSL4 axis-dependent ferroptosis and inflammation promote hypertension-associated chronic kidney disease.
miR-124 and VAMP3 Act Antagonistically in Human Neuroblastoma.
Heme oxygenase-1 increases intracellular iron storage and suppresses inflammatory response of macrophages by inhibiting M1 polarization.
Aspartyl-tRNA synthetase 2 orchestrates iron-sulfur metabolism in hematopoietic stem cells via fine-tuning alternative RNA splicing.
Mechanotransduction in response to ECM stiffening impairs cGAS immune signaling in tumor cells.
Intraperitoneal Injection of MCC950 Inhibits the Progression of Myopia in Form-Deprivation Myopic Mice.
Caveolin-1 scaffolding domain peptide prevents corpus cavernosum fibrosis and erectile dysfunction in bilateral cavernous nerve injury-induced rats.
Lactobacillus casei combined with Lactobacillus reuteri alleviate pancreatic cancer by inhibiting TLR4 to promote macrophage M1 polarization and regulate gut microbial homeostasis.
Comparison of Multiple Strategies for Precision Transgene Knock-In in Gallus gallus Genome via Microhomology-Mediated End Joining.
RNF149 Promotes HCC Progression through Its E3 Ubiquitin Ligase Activity.
Sirtuin1 Mediates the Protective Effects of Echinacoside against Sepsis-Induced Acute Lung Injury via Regulating the NOX4-Nrf2 Axis.
Poria cocos Lanostane Triterpenoids Extract Promotes Collagen and Hyaluronic Acid Production in D-Galactose-Induced Aging Rats.
Liensinine and neferine exert neuroprotective effects via the autophagy pathway in transgenic Caenorhabditis elegans.
METTL3-regulated m6A modification impairs the decidualization of endometrial stromal cells by regulating YTHDF2-mediated degradation of FOXO1 mRNA in endometriosis-related infertility.
Leveraging a disulfidptosis-related signature to predict the prognosis and immunotherapy effectiveness of cutaneous melanoma based on machine learning.
Cordyceps militaris Solid Medium Extract Alleviates Lipoteichoic Acid-Induced MH-S Inflammation by Inhibiting TLR2/NF-κB/NLRP3 Pathways.
Nuclear respiratory factor 1 drives hepatocellular carcinoma progression by activating LPCAT1-ERK1/2-CREB axis.
Metformin inhibits inflammatory response and endoplasmic reticulum stress to improve hypothalamic aging in obese mice.
Dominant-negative HNF1α mutant promotes liver steatosis and inflammation by regulating hepatic complement factor D.
Focused low-intensity pulsed ultrasound alleviates osteoarthritis via restoring impaired FUNDC1-mediated mitophagy.
CHIP protects against septic acute kidney injury by inhibiting NLRP3-mediated pyroptosis.
African Swine Fever Virus pF778R Attenuates Type I Interferon Response by Impeding STAT1 Nuclear Translocation.
Identification of KLHDC2 as an efficient proximity-induced degrader of K-RAS, STK33, β-catenin, and FoxP3.
Insulin-induced gene 2 protects against hepatic ischemia-reperfusion injury via metabolic remodeling.
Targeting neoadjuvant chemotherapy-induced metabolic reprogramming in pancreatic cancer promotes anti-tumor immunity and chemo-response.
Posttranslational ISGylation of NLRP3 by HERC enzymes facilitates inflammasome activation in models of inflammation.
PI3K/mTOR inhibitor VS-5584 combined with PLK1 inhibitor exhibits synergistic anti-cancer effects on non-small cell lung cancer.
Silencing of ATP1A1 attenuates cell membrane disruption by nanosecond electric pulses.
Autophagy modulates the stability of Wee1 and cell cycle G2/M transition.
A unique inflammation-related mechanism by which high-fat diets induce depression-like behaviors in mice.
African swine fever virus MGF360-9L promotes viral replication by degrading the host protein HAX1.
Downregulation of XBP1s aggravates lipopolysaccharide-induced inflammation by promoting NF-κB and NLRP3 pathways' activation in goat endometrial epithelial cells.
Leptin Promotes the Proliferation and Neuronal Differentiation of Neural Stem Cells through the Cooperative Action of MAPK/ERK1/2, JAK2/STAT3 and PI3K/AKT Signaling Pathways.
Flubendazole Enhances the Inhibitory Effect of Paclitaxel via HIF1α/PI3K/AKT Signaling Pathways in Breast Cancer.
METTL3/IGF2BP2 axis affects the progression of colorectal cancer by regulating m6A modification of STAG3.
Peptide Characterization of Bovine Myocardium Hydrolysates and Its Ameliorative Effects on Doxorubicin-Induced Myocardial Injury in H9c2 Cells and in Mice.
AP4M1 as a prognostic biomarker associated with cell proliferation, migration and immune regulation in hepatocellular carcinoma.
Comparing the value of mono- vs coculture for high-throughput compound screening in hematological malignancies.
Cryo-EM structure of severe fever with thrombocytopenia syndrome virus.
Novel c-Myc G4 stabilizer EP12 promotes myeloma cytotoxicity by disturbing NF-κB signaling.
Inulin alleviates neuroinflammation and oxidative stress induced by perinatal 2-ethylhexyl diphenyl phosphate (EHDPHP) exposure in female mice and offspring.
Complement C1q drives microglia-dependent synaptic loss and cognitive impairments in a mouse model of lipopolysaccharide-induced neuroinflammation.
Umbilical cord mesenchymal stem cell-conditioned medium inhibits microglial activation to ameliorate neuroinflammation in amyotrophic lateral sclerosis mice and cell models.
Dendrobium mixture ameliorates hepatic injury induced by insulin resistance in vitro and in vivo through the downregulation of AGE/RAGE/Akt signaling pathway.
Arginase2 mediates contrast-induced acute kidney injury via facilitating nitrosative stress in tubular cells.
Tobacco toxins induce osteoporosis through ferroptosis.
The novel β-TrCP protein isoform hidden in circular RNA confers trastuzumab resistance in HER2-positive breast cancer.
TRIM16 E121D variant affects the risk and prognosis of hepatocellular carcinoma by modulating the Wnt/β-catenin pathway.
LKB1 loss promotes colorectal cancer cell metastasis through regulating TNIK expression and actin cytoskeleton remodeling.
Rutaecarpine Mitigates Cognitive Impairment by Balancing Mitochondrial Function Through Activation of the AMPK/PGC1α Pathway.
A new ferrocene derivative blocks K-Ras localization and function by oxidative modification at His95.
RNA‑binding protein quaking 5 inhibits the progression of non‑small cell lung cancer by upregulating netrin‑4 expression.
LncRNA MALAT1 Promoted Neuronal Necroptosis in Cerebral Ischemia-reperfusion Mice by Stabilizing HSP90.
Ginsenoside Rg5 promotes wound healing in diabetes by reducing the negative regulation of SLC7A11 on the efferocytosis of dendritic cells.
The cysteine-rich receptor-like kinase CRK4 contributes to the different drought stress response between Columbia and Landsberg erecta.
Inhibition of TMEM16A improves cisplatin-induced acute kidney injury via preventing DRP1-mediated mitochondrial fission.
Cardiomyocyte peroxisome proliferator-activated receptor α prevents septic cardiomyopathy via improving mitochondrial function.
Neuroprotective Effect of Hydrogen Sulfide Subchronic Treatment Against TBI-Induced Ferroptosis and Cognitive Deficits Mediated Through Wnt Signaling Pathway.
Inflammatory Cell-Derived MYDGF Attenuates Endothelial LDL Transcytosis to Protect Against Atherogenesis.
UBE3B promotes breast cancer progression by antagonizing HIF-2α degradation.
Fusaric acid inhibits proliferation and induces apoptosis through triggering endoplasmic reticulum stress in MCF-7 human breast cancer cells.
Genetic Architecture and Functional Implications of the CSF-Contacting Nucleus.
UFMylation of HRD1 regulates endoplasmic reticulum homeostasis.
RUNX1 promotes proliferation and migration in non-small cell lung cancer cell lines via the mTOR pathway.
Potent gene delivery from fluorinated poly(β-amino ester) in adhesive and suspension difficult-to-transfect cells for apoptosis and ferroptosis.
Neuropathological hallmarks in autopsied cases with mitochondrial diseases caused by the mitochondrial 3243A>G mutation.
M2 macrophage exosomal LINC01001 promotes non-small cell lung cancer development by affecting METTL3 and glycolysis pathway.
Targeting SOD1 via RNAi with PEGylated graphene oxide nanoparticles in platinum-resistant ovarian cancer.
Combination of hyperlipidemia and 17β-Estradiol induces TMJOA-like pathological changes in rats.
Involvement of ferroptosis in Porphyromonas gingivalis lipopolysaccharide-stimulated periodontitis in vitro and in vivo.
Acetyl zingerone ameliorates osteoarthritis by inhibiting chondrocyte programmed cell death.
Knockdown of Bach1 protects periodontal bone regeneration from inflammatory damage.
Transcriptomics and metabolomics study in mouse kidney of the molecular mechanism underlying energy metabolism response to hypoxic stress in highland areas.
An HPK1 inhibitor enhanced the tumour response to anti-PD-1 immunotherapy in non-Hodgkin's lymphoma.
Mulberry leaf flavonoids activate BAT and induce browning of WAT to improve type 2 diabetes via regulating the AMPK/SIRT1/PGC-1α signaling pathway.
Sphingosine kinase 1/S1P receptor signaling axis is essential for cellular uptake of Neisseria meningitidis in brain endothelial cells.
Autophagy regulation and protein kinase activity of PIK3C3 controls sertoli cell polarity through its negative regulation on SCIN (scinderin).
Ferroptosis inhibition protects vascular endothelial cells and maintains integrity of the blood-spinal cord barrier after spinal cord injury.
Angelica sinensis polysaccharides ameliorated 5-Fluorouracil-induced damage of early B cell progenitors by alleviating oxidative stress of IL-7 producing mesenchymal stem and progenitor cells.
Fructus Lycii and Salvia miltiorrhiza Bunge extract attenuate oxidative stress-induced photoreceptor ferroptosis in retinitis pigmentosa.
Design and synthesis of 3,4-seco-lupane triterpene derivatives to resist myocardial ischemia-reperfusion injury by inhibiting oxidative stress-mediated mitochondrial dysfunction via the PI3K/AKT/HIF-1α axis.
L-arabinose Attenuates LPS-Induced Intestinal Inflammation and Injury through Reduced M1 Macrophage Polarization.
Meroterpenoids from Daphne genkwa shows promising in vitro antitumor activity via inhibiting PI3K/Akt/mTOR signaling pathway in A549 cells.
Effects of the PI3K/Akt/HO-1 pathway on autophagy in a sepsis-induced acute lung injury mouse model.
E3 ubiquitin ligase Siah1 aggravates NAFLD through Scp2 ubiquitination.
Pachymic acid suppresses the inflammatory response of chondrocytes and alleviates the progression of osteoarthritis via regulating the Sirtuin 6/NF-κB signal axis.
The STING inhibitor C-176 attenuates MPTP-induced neuroinflammation and neurodegeneration in mouse parkinsonian models.
Human placental mesenchymal stromal cells modulate IFN-γ and IL-10 secretion by CD4(+)T cells via CD73, and alleviate intestinal damage in mice with graft-versus-host disease.
Glycosides of Buyang Huanwu decoction inhibits pyroptosis associated with cerebral ischemia-reperfusion through Nrf2-mediated antioxidant signaling pathway both in vivo and in vitro.
Mesenchymal stem cell-derived exosomal miR-548x-3p inhibits pyroptosis of vascular endothelial cells through HMGB1 in heat stroke.
Inhibition of STAT-mediated cytokine responses to chemically-induced colitis prevents inflammation-associated neurobehavioral impairments.
KLF5/MDM2 Axis Modulates Oxidative Stress and Epithelial-Mesenchymal Transition in Human Lens Epithelial Cells: The Role in Diabetic Cataract.
Guanxin V alleviates ventricular remodeling by promoting transforming growth factor-beta 1-mediated proteasomal degradation of Vimentin.
The Peptide AWRK6 Alleviates Lipid Accumulation in Hepatocytes by Inhibiting miR-5100 Targeting G6PC.
Aqueous Extract of Brassica rapa L.'s Impact on Modulating Exercise-Induced Fatigue via Gut-Muscle Axis.
Hyperoside Protects Trastuzumab-Induced Cardiotoxicity via Activating the PI3K/Akt Signaling Pathway.
Duck Tembusu virus induces incomplete autophagy via the ERK/mTOR and AMPK/mTOR signalling pathways to promote viral replication in neuronal cells.
Bone marrow immune cells respond to fluctuating nutritional stress to constrain weight regain.
Cuproptosis-related gene DLAT serves as a prognostic biomarker for immunotherapy in clear cell renal cell carcinoma: multi-database and experimental verification.
An ULK1/2-PXN mechanotransduction pathway suppresses breast cancer cell migration.
Chromofungin, a chromogranin A-derived peptide, protects against sepsis-induced acute lung injury by inhibiting LBP/TLR4-dependent inflammatory signaling.
Discovery of a novel dual-target inhibitor of CDK12 and PARP1 that induces synthetic lethality for treatment of triple-negative breast cancer.
Cell volume controlled by LRRC8A-formed volume-regulated anion channels fine-tunes T cell activation and function.
PGAM5 degrades PDCoV N protein and activates type I interferon to antagonize viral replication.
Alphavirus-based replicons demonstrate different interactions with host cells and can be optimized to increase protein expression.
Jun-APOE-LRP1 axis promotes tumor metastasis in colorectal cancer.
Selective activator of human ClpP triggers cell cycle arrest to inhibit lung squamous cell carcinoma.
Spliceosome component Usp39 contributes to hepatic lipid homeostasis through the regulation of autophagy.
A bacteria-derived tetramerized protein ameliorates nonalcoholic steatohepatitis in mice via binding and relocating acetyl-coA carboxylase.
Targeting PRMT1-mediated SRSF1 methylation to suppress oncogenic exon inclusion events and breast tumorigenesis.
Kaempferol Improves Breast Cancer-Related Depression through the COX-2/PGE2 Pathway.
A Mild Hyperthermia Hollow Carbon Nanozyme as Pyroptosis Inducer for Boosted Antitumor Immunity.
LSM14B is essential for oocyte meiotic maturation by regulating maternal mRNA storage and clearance.
FUNDC2, a mitochondrial outer membrane protein, mediates triple-negative breast cancer progression via the AKT/GSK3β/GLI1 pathway.
Intervention of Tanshinone IIA on the PGK1-PDHK1 Pathway to Reprogram Macrophage Phenotype After Myocardial Infarction.
The Protective Effects of Reineckia carnea Ether Fraction against Alzheimer's Disease Pathology: An Exploration in Caenorhabditis elegans Models.
RGS5 maintaining vascular homeostasis is altered by the tumor microenvironment.
Progesterone Activates the Histone Lactylation-Hif1α-glycolysis Feedback Loop to Promote Decidualization.
Attenuation of estrogen and its receptors in the post-menopausal stage exacerbates dyslipidemia and leads to cognitive impairment.
Cinnamaldehyde Alleviates Bone Loss by Targeting Oxidative Stress and Mitochondrial Damage via the Nrf2/HO-1 Pathway in BMSCs and Ovariectomized Mice.
Iron derived from NCOA4-mediated ferritinophagy causes cellular senescence via the cGAS-STING pathway.
Ferroptosis sensitization in glioma: exploring the regulatory mechanism of SOAT1 and its therapeutic implications.
ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury.
DLX2 promotes osteosarcoma epithelial-mesenchymal transition and doxorubicin resistance by enhancing HOXC8-CDH2 axis.
AKAP150 from nucleus accumbens dopamine D1 and D2 receptor-expressing medium spiny neurons regulates morphine withdrawal.
Cullin 5 aggravates hypoxic pulmonary hypertension by activating TRAF6/NF-κB/HIF-1α/VEGF.
Oral pathogens exacerbate Parkinson's disease by promoting Th1 cell infiltration in mice.
Blockage of CacyBP inhibits macrophage recruitment and improves anti-PD-1 therapy in hepatocellular carcinoma.
Simvastatin induces pyroptosis via ROS/caspase-1/GSDMD pathway in colon cancer.
Development of decoy oligonucleotide-warheaded chimeric molecules targeting STAT3.
Structural determinants specific for retromer protein sorting nexin 5 in regulating subcellular retrograde membrane trafficking.
Inhibition of METTL3 alleviated LPS-induced alveolar epithelial cell apoptosis and acute lung injury via restoring neprilysin expression.
Discovery of potent pyrrolo-pyrimidine and purine HDAC inhibitors for the treatment of advanced prostate cancer.
Sclerotome-derived PDGF signaling functions as a niche cue responsible for primitive erythropoiesis.
Polyamine metabolism controls B-to-Z DNA transition to orchestrate DNA sensor cGAS activity.
Interactome profiling of Crimean-Congo hemorrhagic fever virus glycoproteins.
The hippocampal FTO-BDNF-TrkB pathway is required for novel object recognition memory reconsolidation in mice.
Curcumin enhances elvitegravir concentration and alleviates oxidative stress and inflammatory response.
Ubc9 regulates the expression of MHC II in dendritic cells to enhance DSS-induced colitis by mediating RBPJ SUMOylation.
Identification of OLA1 as a Novel Protein Target of Vitexin to Ameliorate Dextran Sulfate Sodium-Induced Colitis with Tissue Thermal Proteome Profiling.
Phlorizin Mitigates Dextran Sulfate Sodium-Induced Colitis in Mice by Modulating Gut Microbiota and Inhibiting Ferroptosis.
Col3a1 delivered via extracellular vesicles of Sertoli cells is essential for mice Sertoli cell proliferation.
Oncogene SCARNA12 as a potential diagnostic biomarker for colorectal cancer.
Genome-Wide CRISPR/Cas9 Screening Identifies That Mitochondrial Solute Carrier SLC25A23 Attenuates Type I IFN Antiviral Immunity via Interfering with MAVS Aggregation.
Soluble epoxide hydrolase deficiency attenuates airway inflammation in COPD via IRE1α/JNK/AP-1 signaling pathway.
Follicle-stimulating hormone orchestrates glucose-stimulated insulin secretion of pancreatic islets.
A human mitofusin 2 mutation can cause mitophagic cardiomyopathy.
Photobiomodulation augments the effects of mitochondrial transplantation in the treatment of spinal cord injury in rats by facilitating mitochondrial transfer to neurons via Connexin 36.
Triptolide injection reduces Alzheimer's disease-like pathology in mice.
GSTP1-mediated S-glutathionylation of Pik3r1 is a redox hub that inhibits osteoclastogenesis through regulating autophagic flux.
Relationship between IL-22 and IL-22BP in diabetic cognitive dysfunction.
Segregation of pathways leading to pexophagy.
MSC-EXO and tempol ameliorate bronchopulmonary dysplasia in newborn rats by activating HIF-1α.
Cannabinoid type 2 receptor activation inhibits MPP(+)-induced M1 differentiation of microglia through activating PI3K/Akt/Nrf2 signal pathway.
Discovery of a natural small-molecule AMP-activated kinase activator that alleviates nonalcoholic steatohepatitis.
Apelin-13 Improves Cognitive Impairment and Repairs Hippocampal Neuronal Damage by Activating PGC-1α/PPARγ Signaling.
TRPM8 promotes hepatocellular carcinoma progression by inducing SNORA55 mediated nuclear-mitochondrial communication.
PKM2 allosteric converter: A self-assembly peptide for suppressing renal cell carcinoma and sensitizing chemotherapy.
Staphylococcus aureus induces mitophagy to promote its survival within bovine mammary epithelial cells.
CD98 regulates the phosphorylation of HER2 and a bispecific anti-HER2/CD98 antibody inhibits the growth signal of human breast cancer cells.
Curcumin protects against doxorubicin induced oxidative stress by regulating the Keap1-Nrf2-ARE and autophagy signaling pathways.
Lipid phosphatase SAC1 suppresses hepatitis B virus replication through promoting autophagic degradation of virions.
HIF-1α Mediates Arsenic-Induced Metabolic Reprogramming in Lung Bronchial Epithelial Cells.
Proline promotes proliferation and drug resistance of multiple myeloma by downregulation of proline dehydrogenase.
Themis suppresses the effector function of CD8(+) T cells in acute viral infection.
Novel secreted STPKLRR from Vibrio splendidus AJ01 promotes pathogen internalization via mediating tropomodulin phosphorylation dependent cytoskeleton rearrangement.
EphA2 is a functional entry receptor for HCMV infection of glioblastoma cells.
Bisphenol P exposure in C57BL/6 mice caused gut microbiota dysbiosis and induced intestinal barrier disruption via LPS/TLR4/NF-κB signaling pathway.
CDGSH iron sulfur domain 2 over-expression alleviates neuronal ferroptosis and brain injury by inhibiting lipid peroxidation via AKT/mTOR pathway following intracerebral hemorrhage in mice.
Targeting ZDHHC9 potentiates anti-programmed death-ligand 1 immunotherapy of pancreatic cancer by modifying the tumor microenvironment.
CBL0137 activates ROS/BAX signaling to promote caspase-3/GSDME-dependent pyroptosis in ovarian cancer cells.
The impact and mechanism of TET3 overexpression on the progression of hepatic fibrosis.
Characterization and mechanisms of radioresistant lung squamous cell carcinoma cell lines.
High-frequency repetitive transcranial magnetic stimulation protects against cerebral ischemia/reperfusion injury in rats: Involving the mitigation of ferroptosis and inflammation.
NSUN2-mediated m(5) C RNA methylation dictates retinoblastoma progression through promoting PFAS mRNA stability and expression.
Integrating HPLC-Q-TOF-MS/MS, network pharmacology and experimental validation to decipher the chemical substances and mechanism of modified Gui-shao-liu-jun-zi decoction against gastric cancer.
Extracellular vesicles derived from Akkermansia muciniphila promote placentation and mitigate preeclampsia in a mouse model.
d-mannose blocks the interaction between keratinocytes and Th17 cells to alleviate psoriasis by inhibiting HIF-1α/CCL20 in mice.
Tanshinone IIA analogue 15a inhibits NLRP3-mediated inflammation by activating mitophagy in macrophages to alleviate acute tubular necrosis.
C1q/tumor necrosis factor-related protein-9 exerts antioxidant and anti-inflammatory effects on oxygen-glucose deprivation/reoxygenation-stimulated neurons by modulating the Akt-GSK-3β-Nrf2 cascade via AdipoR1.
Highly pathogenic porcine reproductive and respiratory syndrome virus-induced inflammatory response in porcine pulmonary microvascular endothelial cells and effects of herbal ingredients on main inflammatory molecules.
Prognosis-related VDAC1 regulates the proliferation and apoptosis of osteosarcoma cells via the MAPK signaling pathway.
Loureirin C inhibits ferroptosis after cerebral ischemia reperfusion through regulation of the Nrf2 pathway in mice.
Rs15285, a functional polymorphism located in lipoprotein lipase, predicts the risk and prognosis of gastric cancer.
Orai1 is an Entotic Ca(2+) Channel for Non-Apoptotic Cell Death, Entosis in Cancer Development.
Astaxanthin protects human ARPE-19 retinal pigment epithelium cells from blue light-induced phototoxicity by scavenging singlet oxygen.
Resistance to anti-HER2 therapy associated with the TSC2 nonsynonymous variant c.4349 C > G (p.Pro1450Arg) is reversed by CDK4/6 inhibitor in HER2-positive breast cancer.
ER-localized JmjC domain-containing protein JMJD8 targets STING to promote immune evasion and tumor growth in breast cancer.
The relationship between gut microbiota and susceptibility to type 2 diabetes mellitus in rats.
The Screening of Broadly Neutralizing Antibodies Targeting the SARS-CoV-2 Spike Protein by mRNA Immunization in Mice.
Mitochondrial Glycerol-3-Phosphate Dehydrogenase Restricts HBV Replication via the TRIM28-Mediated Degradation of HBx.
Pancreatic tumors exhibit myeloid-driven amino acid stress and upregulate arginine biosynthesis.
Epsin1-mediated exosomal sorting of Dll4 modulates the tubular-macrophage crosstalk in diabetic nephropathy.
Targeting copper death genotyping associated gene RARRES2 suppresses glioblastoma progression and macrophages infiltration.
Pulsatilla Decoction and its bioactive component β-peltatin induce G2/M cell cycle arrest and apoptosis in pancreatic cancer.
Anti-Neuroinflammatory Meroterpenoids from a Chinese Collection of the Brown Alga Sargassum siliquastrum.
The Nrf2/HMGB1/NF-κB axis modulates chondrocyte apoptosis and extracellular matrix degradation in osteoarthritis.
Apolipoprotein A4 Elevates Sympathetic Activity and Thermogenesis in Male Mice.
High Level of GMFG Correlated to Poor Clinical Outcome and Promoted Cell Migration and Invasion through EMT Pathway in Triple-Negative Breast Cancer.
miR-199a-5p from bone marrow mesenchymal stem cell exosomes promotes the proliferation of neural stem cells by targeting GSK-3β.
Rhein Inhibited Ferroptosis and EMT to Attenuate Diabetic Nephropathy by Regulating the Rac1/NOX1/β-Catenin Axis.
The FBXO32/ATR/ATM axis acts as a molecular switch to control the sensitivity of osteosarcoma cells to irradiation through its regulation of EXO1 expression.
TMT proteomics analysis reveals the mechanism of bleomycin-induced pulmonary fibrosis and effects of Ginseng honeysuckle superfine powdered tea.
Ambra1 modulates the sensitivity of mantle cell lymphoma to palbociclib by regulating cyclin D1.
Hydroxysafflor yellow a confers neuroprotection against acute traumatic brain injury by modulating neuronal autophagy to inhibit NLRP3 inflammasomes.
All-Trans Retinoic Acid-Responsive LGR6 Is Transiently Expressed during Myogenic Differentiation and Is Required for Myoblast Differentiation and Fusion.
RBM10 Loss Promotes EGFR-Driven Lung Cancer and Confers Sensitivity to Spliceosome Inhibition.
Reduced hepatic bradykinin degradation accounts for cold-induced BAT thermogenesis and WAT browning in male mice.
Epigenetically silenced lncRNA SNAI3-AS1 promotes ferroptosis in glioma via perturbing the m(6)A-dependent recognition of Nrf2 mRNA mediated by SND1.
Multi-omics analysis of a drug-induced model of bipolar disorder in zebrafish.
MRPL12-ANT3 interaction involves in acute kidney injury via regulating MPTP of tubular epithelial cells.
Amphibian pore-forming protein βγ-CAT drives extracellular nutrient scavenging under cell nutrient deficiency.
C9ORF72 suppresses JAK-STAT mediated inflammation.
Transcription factor Dmrt1 triggers the SPRY1-NF-κB pathway to maintain testicular immune homeostasis and male fertility.
Evaluation of different rat models intrauterine adhesion models and improvement of the technique for their establishment.
miR-100-5p Regulates Skeletal Muscle Myogenesis through the Trib2/mTOR/S6K Signaling Pathway.
Adiponectin Attenuates Splenectomy-Induced Cognitive Deficits by Neuroinflammation and Oxidative Stress via TLR4/MyD88/NF-κb Signaling Pathway in Aged Rats.
The High Level of RANKL Improves IκB/p65/Cyclin D1 Expression and Decreases p-Stat5 Expression in Firm Udder of Dairy Goats.
Recognition Mechanism of a Novel Gabapentinoid Drug, Mirogabalin, for Recombinant Human α(2)δ1, a Voltage-Gated Calcium Channel Subunit.
CircPVT1 promotes ER-positive breast tumorigenesis and drug resistance by targeting ESR1 and MAVS.
Interaction of Nmi and IFP35 Promotes Mutual Protein Stabilization and IRF3 and IRF7 Degradation to Suppress Type I IFN Production in Teleost Fish.
FOXA2 plays a critical role in hepatocellular carcinoma progression and lenvatinib-associated drug resistance.
Elevated nuclear TDP-43 induces constitutive exon skipping.
Structure of Semliki Forest virus in complex with its receptor VLDLR.
Lactiplantibacillus plantarum attenuates Coxsackievirus B3-induced pancreatitis through the BAX/BCL2/CASP3 signaling pathway.
Effect of Sublethal Concentrations of Metal Nanomaterials on Cell Energy Metabolism.
Interleukin-1 increases cyclooxygenase-2 expression and prostaglandin E2 production in human granulosa-lutein cell via nuclear factor kappa B/P65 and extracellular signal-regulated kinase 1/2 signaling pathways.
Cancer-associated fibroblasts suppressed ferroptosis in glioblastoma via upregulating lncRNA DLEU1.
EVL and MIM/MTSS1 regulate actin cytoskeletal remodeling to promote dendritic filopodia in neurons.
Soluble TREM-like Transcript-1 Acts as a Damage-Associated Molecular Pattern through the TLR4/MD2 Pathway Contributing to Immune Dysregulation during Sepsis.
Cardiac-specific Trim44 knockout in rat attenuates isoproterenol-induced cardiac remodeling via inhibition of AKT/mTOR pathway.
FBXO11 amplifies type I interferon signaling to exert antiviral effects by facilitating the assemble of TRAF3-TBK1-IRF3 complex.
SARS-CoV-2 Omicron XBB subvariants exhibit enhanced fusogenicity and substantial immune evasion in elderly population, but high sensitivity to pan-coronavirus fusion inhibitors.
ZNFX1 antisense RNA1 promotes antiviral innate immune responses via modulating ZNFX1 function.
Ubiquitin E3 ligase β-TrCP negatively regulates surface protein of hepatitis B virus.
SARS-CoV-2 NSP7 inhibits type I and III IFN production by targeting the RIG-I/MDA5, TRIF, and STING signaling pathways.
ATG16L1 adopts a dual-binding site mode to interact with WIPI2b in autophagy.
YY1 (Yin-Yang 1), a transcription factor regulating systemic inflammation, is involved in cognitive impairment of depression.
A Disintegrin and Metalloproteinase 10 (ADAM10) Is Essential for Oligodendrocyte Precursor Development and Myelination in the Mouse Brain.
An unconventional cancer-promoting function of methamphetamine in hepatocellular carcinoma.
GBP2 promotes clear cell renal cell carcinoma progression through immune infiltration and regulation of PD‑L1 expression via STAT1 signaling.
Effects of icariin and curcumol on autophagy, ferroptosis, and lipid metabolism based on miR-7/m-TOR/SREBP1 pathway on prostate cancer.
Methionine sulfoxide suppresses adipogenic differentiation by regulating the mitogen-activated protein kinase signaling pathway.
RASSF1A inhibits epithelial-mesenchymal transition of gastric cancer cells by downregulating P-JNK.
Ginsenoside compound K reduces ischemia/reperfusion-induced neuronal apoptosis by inhibiting PTP1B-mediated IRS1 tyrosine dephosphorylation.
p52-ZER6: a determinant of tumor cell sensitivity to MDM2-p53 binding inhibitors.
The E3 ligase RBCK1 reduces the sensitivity of ccRCC to sunitinib through the ANKRD35-MITD1-ANXA1 axis.
hASCs-derived exosomal miR-155-5p targeting TGFβR2 promotes autophagy and reduces pyroptosis to alleviate intervertebral disc degeneration.
Cerebrospinal fluid-derived extracellular vesicles after spinal cord injury promote vascular regeneration via PI3K/AKT signaling pathway.
Linear ubiquitination of LKB1 activates AMPK pathway to inhibit NLRP3 inflammasome response and reduce chondrocyte pyroptosis in osteoarthritis.
miR-124-3p improves mitochondrial function of renal tubular epithelial cells in db/db mice.
A Physiologically Responsive Nanocomposite Hydrogel for Treatment of Head and Neck Squamous Cell Carcinoma via Proteolysis-Targeting Chimeras Enhanced Immunotherapy.
HSP90β promotes osteoclastogenesis by dual-activation of cholesterol synthesis and NF-κB signaling.
Glioblastoma glycolytic signature predicts unfavorable prognosis, immunological heterogeneity, and ENO1 promotes microglia M2 polarization and cancer cell malignancy.
Transcription factor SOX15 regulates stem cell pluripotency and promotes neural fate during differentiation by activating the neurogenic gene Hes5.
USP22 suppresses the NLRP3 inflammasome by degrading NLRP3 via ATG5-dependent autophagy.
SDC1-dependent TGM2 determines radiosensitivity in glioblastoma by coordinating EPG5-mediated fusion of autophagosomes with lysosomes.
Liraglutide abrogates nephrotoxic effects of chemotherapies.
Chronic spinal cord compression associated with intervertebral disc degeneration in SPARC-null mice.
Ectopic endometriotic stromal cells-derived lactate induces M2 macrophage polarization via Mettl3/Trib1/ERK/STAT3 signalling pathway in endometriosis.
The Effect of Gut Microbiota on the Progression of Intervertebral Disc Degeneration.
Hesperidin enhances intestinal barrier function in Caco-2 cell monolayers via AMPK-mediated tight junction-related proteins.
Thioredoxin 1 overexpression attenuated diabetes-induced endoplasmic reticulum stress in Müller cells via apoptosis signal-regulating kinase 1.
Antidepressant-like effect of CP-101,606: Evidence of mTOR pathway activation.
Metabolism-related lncRNAs signature to predict the prognosis of colon adenocarcinoma.
Developmental changes in lipid and fatty acid metabolism and the inhibition by in ovo feeding oleic acid in Muscovy duck embryogenesis.
Lin28a induced mitochondrial dysfunction in human granulosa cells via suppressing LARS2 expression.
Guanylate-binding protein 1 restricts avian coronavirus infectious bronchitis virus-infected HD11 cells.
Uridine Alleviates Sepsis-Induced Acute Lung Injury by Inhibiting Ferroptosis of Macrophage.
p53 directly downregulates the expression of CDC20 to exert anti-tumor activity in mantle cell lymphoma.
Effects of Caprylic Acid and Eicosapentaenoic Acid on Lipids, Inflammatory Levels, and the JAK2/STAT3 Pathway in ABCA1-Deficient Mice and ABCA1 Knock-Down RAW264.7 Cells.
Isopropyl 3-(3, 4-dihydroxyphenyl)-2-hydroxypropanoate protects lipopolysaccharide-induced acute lung injury in mice by attenuating pyroptosis.
Sertaconazole nitrate targets IDO1 and regulates the MAPK signaling pathway to induce autophagy and apoptosis in CRC cells.
PKM2/PDK1 dual-targeted shikonin derivatives restore the sensitivity of EGFR-mutated NSCLC cells to gefitinib by remodeling glucose metabolism.
DNA repair mechanisms that promote insertion-deletion events during immunoglobulin gene diversification.
The stromal-tumor amplifying STC1-Notch1 feedforward signal promotes the stemness of hepatocellular carcinoma.
Ferredoxin 1 regulates granulosa cell apoptosis and autophagy in polycystic ovary syndrome.
Sustainably released nanoparticle-based rhynchophylline limits pulmonary fibrosis by inhibiting the TEK-PI3K/AKT signaling pathway.
9-Butyl-Harmol Exerts Antiviral Activity against Newcastle Disease Virus through Targeting GSK-3β and HSP90β.
All Domains of SARS-CoV-2 nsp1 Determine Translational Shutoff and Cytotoxicity of the Protein.
Newcastle Disease Virus Manipulates Mitochondrial MTHFD2-Mediated Nucleotide Metabolism for Virus Replication.
Theabrownin Isolated from Pu-Erh Tea Enhances the Innate Immune and Anti-Inflammatory Effects of RAW264.7 Macrophages via the TLR2/4-Mediated Signaling Pathway.
RPL11 promotes non-small cell lung cancer cell proliferation by regulating endoplasmic reticulum stress and cell autophagy.
PVT1/miR-136/Sox2/UPF1 axis regulates the malignant phenotypes of endometrial cancer stem cells.
Comprehensive proteogenomic characterization of early duodenal cancer reveals the carcinogenesis tracks of different subtypes.
A new ferrocene derivative blocks KRAS localization and function by oxidative modification at His95.
Baicalin facilitates remyelination and suppresses neuroinflammation in rats with chronic cerebral hypoperfusion by activating Wnt/β-catenin and inhibiting NF-κB signaling.
Role of Berberine Thermosensitive Hydrogel in Periodontitis via PI3K/AKT Pathway In Vitro.
PARM1 Drives Smooth Muscle Cell Proliferation in Pulmonary Arterial Hypertension via AKT/FOXO3A Axis.
Identification of biomarkers of hepatocellular carcinoma gene prognosis based on the immune-related lncRNA signature of transcriptome data.
Hyperglycemia induces PFKFB3 overexpression and promotes malignant phenotype of breast cancer through RAS/MAPK activation.
CD137 signaling aggravates myocardial ischemia-reperfusion injury by inhibiting mitophagy mediated NLRP3 inflammasome activation.
Downregulated annexin A1 expression correlates with poor prognosis, metastasis, and immunosuppressive microenvironment in Ewing's sarcoma.
The Construction and Immunogenicity Analyses of a Recombinant Pseudorabies Virus with Senecavirus A VP2 Protein Coexpression.
Microglial aryl hydrocarbon receptor enhances phagocytic function via SYK and promotes remyelination in the cuprizone mouse model of demyelination.
FZD7, Regulated by Non-CpG Methylation, Plays an Important Role in Immature Porcine Sertoli Cell Proliferation.
The rhythmic coupling of Egr-1 and Cidea regulates age-related metabolic dysfunction in the liver of male mice.
Podocyte-specific deletion of ubiquitin carboxyl-terminal hydrolase L1 causes podocyte injury by inducing endoplasmic reticulum stress.
The OTUD1-Notch2-ICD axis orchestrates allogeneic T cell-mediated graft-versus-host disease.
p38-mediated FOXN3 phosphorylation modulates lung inflammation and injury through the NF-κB signaling pathway.
Activating mitofusins interrupts mitochondrial degeneration and delays disease progression in SOD1 mutant amyotrophic lateral sclerosis.
Prediction and Verification of Curcumin as a Potential Drug for Inhibition of PDCoV Replication in LLC-PK1 Cells.
TUBA1C: a new potential target of LncRNA EGFR-AS1 promotes gastric cancer progression.
Dietary choline metabolite TMAO impairs cognitive function and induces hippocampal synaptic plasticity declining through the mTOR/P70S6K/4EBP1 pathway.
Aberrant Activation of the STING-TBK1 Pathway in γδ T Cells Regulates Immune Responses in Oral Lichen Planus.
Secreted protease PRSS35 suppresses hepatocellular carcinoma by disabling CXCL2-mediated neutrophil extracellular traps.
An XBP1s-PIM-2 positive feedback loop controls IL-15-mediated survival of natural killer cells.
PPT1 regulation of HSP90α depalmitoylation participates in the pathogenesis of hyperandrogenism.
Hsp22 pretreatment protects against LPS-induced hippocampal injury by alleviating neuroinflammation and apoptosis by regulating the NLRP3/Caspase1/IL-1β signaling pathway in mice.
SIM imaging resolves endocytosis of SARS-CoV-2 spike RBD in living cells.
Efficient tumor synergistic chemoimmunotherapy by self-augmented ROS-responsive immunomodulatory polymeric nanodrug.
DnaJC7 specifically regulates tau seeding.
Proteome profiling of the prefrontal cortex of Fmr1 knockout mouse reveals enhancement of complement and coagulation cascades.
RIG-I Promotes Tumorigenesis and Confers Radioresistance of Esophageal Squamous Cell Carcinoma by Regulating DUSP6.
Combination therapy with ultrasound and 2D nanomaterials promotes recovery after spinal cord injury via Piezo1 downregulation.
CENP-I directly targets centromeric DNA to support CENP-A deposition and centromere maintenance.
IFIT2 Depletion Promotes Cancer Stem Cell-like Phenotypes in Oral Cancer.
Vascular Endothelial Growth Factor A Contributes to Increased Mammalian Respiratory Epithelial Permeability Induced by Pasteurella multocida Infection.
A novel cuproptosis-related gene signature to predict prognosis in Glioma.
Adipocyte YTH N(6)-methyladenosine RNA-binding protein 1 protects against obesity by promoting white adipose tissue beiging in male mice.
CCP1, a Regulator of Tubulin Post-Translational Modifications, Potentially Plays an Essential Role in Cerebellar Development.
Canagliflozin ameliorates the development of NAFLD by preventing NLRP3-mediated pyroptosis through FGF21-ERK1/2 pathway.
The Qi-Bang-Yi-Shen formula ameliorates renal dysfunction and fibrosis in rats with diabetic kidney disease via regulating PI3K/AKT, ERK and PPARγ signaling pathways.
Pinellia ternata lectin induces inflammation through TLR4 receptor and mediates PI3K/Akt/mTOR axis to regulate NF-κB signaling pathway.
Effects and mechanisms of Xiaochaihu Tang against liver fibrosis: An integration of network pharmacology, molecular docking and experimental validation.
Exploring the potential of ginseng glycoprotein to improve learning and memory in mice via Notch signaling pathway and structural analysis using multi-information fusion based on liquid chromatography-mass spectrometry.
Identification of menaquinone-4 (vitamin K2) target genes in bovine endometrial epithelial cells in vitro.
Gold nanoparticles inhibit tumor growth via targeting the Warburg effect in a c-Myc-dependent way.
TP63 gain-of-function mutations cause premature ovarian insufficiency by inducing oocyte apoptosis.
CRISPR/Cas9 screen uncovers functional translation of cryptic lncRNA-encoded open reading frames in human cancer.
SARS-CoV-2 NSP13 interacts with host IRF3, blocking antiviral immune responses.
TMEM2 induces epithelial-mesenchymal transition and promotes resistance to temozolomide in GBM cells.
Glutaredoxin 1 protects lens epithelial cells from epithelial-mesenchymal transition by preventing casein kinase 1α S-glutathionylation during posterior capsular opacification.
Exercise improves homeostasis of the intestinal epithelium by activation of apelin receptor-AMP-activated protein kinase signalling.
Dysfunction of NRG1/ErbB4 Signaling in the Hippocampus Might Mediate Long-term Memory Decline After Systemic Inflammation.
The YTHDC1/GLUT3/RNF183 axis forms a positive feedback loop that modulates glucose metabolism and bladder cancer progression.
ARID3A plays a key regulatory role in palmitic acid-stimulated milk fat synthesis in mouse mammary epithelial cells.
TLR2-mediated NF-κB signaling pathway is involved in PPV1-induced apoptosis in PK-15 cells.
Chlorogenic Acid Alleviates Hepatic Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress, Inflammation, and Mitochondria-Mediated Apoptosis In Vivo and In Vitro.
Thioredoxin-1 regulates IRE1α to ameliorate sepsis-induced NLRP3 inflammasome activation and oxidative stress in Raw 264.7 cell.
Tabersonine, a natural NLRP3 inhibitor, suppresses inflammasome activation in macrophages and attenuate NLRP3-driven diseases in mice.
Quantitative proteomics of sperm tail in asthenozoospermic patients: exploring the molecular pathways affecting sperm motility.
Hawthorn fruit extract protect against MC-LR-induced hepatotoxicity by attenuating oxidative stress and apoptosis.
A novel nano material for anti-cerebral ischaemia: preparation and application of borneol angelica polysaccharide liposomes.
Loss of exosomal miR-200b-3p from hypoxia cancer-associated fibroblasts promotes tumorigenesis and reduces sensitivity to 5-Flourouracil in colorectal cancer via upregulation of ZEB1 and E2F3.
A Genome-Wide Association Study for Susceptibility to Axial Length in Highly Myopic Eyes.
Oculocerebrorenal syndrome of Lowe (OCRL) controls leukemic T-cell survival by preventing excessive PI(4,5)P(2) hydrolysis in the plasma membrane.
Disruption of the ADAM17/NF-κB feedback loop in astrocytes ameliorates HIV-1 Tat-induced inflammatory response and neuronal death.
Baicalin and baicalein attenuate hyperuricemic nephropathy via inhibiting PI3K/AKT/NF-κB signalling pathway.
Donor graft METTL3 gene transfer ameliorates rat liver transplantation ischemia-reperfusion injury by enhancing HO-1 expression in an m(6)A-dependent manner.
BACH1 promotes intervertebral disc degeneration by regulating HMOX1/GPX4 to mediate oxidative stress, ferroptosis, and lipid metabolism in nucleus pulposus cells.
Silencing of FAM111B inhibits tumor growth and promotes apoptosis by decreasing AKT activity in ovarian cancer.
Upregulation of CSNK1A1 induced by ITGB5 confers to hepatocellular carcinoma resistance to sorafenib in vivo by disrupting the EPS15/EGFR complex.
Charged multivesicular body protein 2B ameliorates biliary injury in the liver from donation after cardiac death rats via autophagy with air-oxygenated normothermic machine perfusion.
Discovery of alantolactone as a naturally occurring NLRP3 inhibitor to alleviate NLRP3-driven inflammatory diseases in mice.
Ginsenoside Rb1 improves energy metabolism after spinal cord injury.
An integrated strategy combining network toxicology and feature-based molecular networking for exploring hepatotoxic constituents and mechanism of Epimedii Folium-induced hepatotoxicity in vitro.
MiR-5622-3p inhibits ZCWPW1 to induce apoptosis in silica-exposed mice and spermatocyte cells.
Baicalin ameliorates multidrug-resistant Pseudomonas aeruginosa induced pulmonary inflammation in rat via arginine biosynthesis.
NPTX2 Promotes Epithelial-Mesenchymal Transition in Cutaneous Squamous Cell Carcinoma through METTL3-Mediated N6-Methyladenosine Methylation of SNAIL.
Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer.
Anti-oxidative-initiated cognitive impairment amelioration in Alzheimer's disease model rats through preventive transcutaneous electrical acupoint stimulation.
Piperine ameliorates psoriatic skin inflammation by inhibiting the phosphorylation of STAT3.
Inflachromene inhibits intimal hyperplasia through the HMGB1/2- regulated TLR4-NF-κB pathway.
Escherichia coli enhances Th17/Treg imbalance via TLR4/NF-κB signaling pathway in oral lichen planus.
Characterizing the specific mechanism of series processed Coptidis Rhizoma by multi-organ metabolomics combined with network pharmacology and molecular docking.
Effect of STK3 on proliferation and apoptosis of pancreatic cancer cells via PI3K/AKT/mTOR pathway.
Elevated expression of myosin VI contributes to breast cancer progression via MAPK/ERK signaling pathway.
Wnt3a-Loaded Extracellular Vesicles Promote Alveolar Epithelial Regeneration after Lung Injury.
Discovery of a New-Generation S-Adenosylmethionine-Noncompetitive Covalent Inhibitor Targeting the Lysine Methyltransferase Enhancer of Zeste Homologue 2.
Silencing mouse circular RNA circSlc8a1 by circular antisense cA-circSlc8a1 induces cardiac hepatopathy.
A copper complex that combats triple negative breast cancer by restraining angiogenesis.
Taurochenodeoxycholic acid inhibits intestinal epithelial cell proliferation and induces apoptosis independent of the farnesoid X receptor.
Discovery of bipyridine amide derivatives targeting pRXRα-PLK1 interaction for anticancer therapy.
Preparation of nanocomposite membranes loaded with taxifolin liposome and its mechanism of wound healing in diabetic mice.
Role of ionizing radiation activated NRF2 in lung cancer radioresistance.
MAGOH is correlated with poor prognosis and is essential for cell proliferation in lower-grade glioma.
AAV9-Tspyl2 gene therapy retards bleomycin-induced pulmonary fibrosis by modulating downstream TGF-β signaling in mice.
DnaJC7 specifically regulates tau seeding.
APOBEC3B coordinates R-loop to promote replication stress and sensitize cancer cells to ATR/Chk1 inhibitors.
CircHIPK3 negatively regulates autophagy by blocking VCP binding to the Beclin 1 complex in bladder cancer.
Palmitoylation at Residue C221 of Japanese Encephalitis Virus NS2A Protein Contributes to Viral Replication Efficiency and Virulence.
Circulating LPS from gut microbiota leverages stenosis-induced deep vein thrombosis in mice.
A core NRF2 gene set defined through comprehensive transcriptomic analysis predicts selective drug resistance and poor multi-cancer prognosis.
Down-regulation of the Smad signaling by circZBTB46 via the Smad2-PDLIM5 axis to inhibit type I collagen expression.
GATA zinc finger protein p66β promotes breast cancer cell migration by acting as a co-activator of Snail.
Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration.
The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-κB.
The Benefits of Nanosized Magnesium Oxide in Fish Megalobrama amblycephala: Evidence in Growth Performance, Redox Defense, Glucose Metabolism, and Magnesium Homeostasis.
Notch mediates the glycolytic switch via PI3K/Akt signaling to support embryonic development.
SIAH1/CTR9 axis promotes the epithelial-mesenchymal transition of hepatocellular carcinoma.
Perturbation of endoplasmic reticulum proteostasis triggers tissue injury in the thyroid gland.
Ginsenoside Rk3 Regulates Nonalcoholic Steatohepatitis by Modulation of Intestinal Flora and the PI3K/AKT Signaling Pathway in C57BL/6 Mice.
C-X-C Motif Chemokine 3 Promotes the Inflammatory Response of Microglia after Escherichia coli-Induced Meningitis.
METTL16 promotes glycolytic metabolism reprogramming and colorectal cancer progression.
Profiling the metabolome of uterine fluid for early detection of ovarian cancer.
ULK1-mediated metabolic reprogramming regulates Vps34 lipid kinase activity by its lactylation.
Chemo- and Diastereoselective Cycloisomerization/[2 + 3] Cycloaddition of Enynamides: Synthesis of Spiropyrazolines as Potential Anticancer Reagents.
Effects of Si-Miao-Yong-An decoction on myocardial I/R rats by regulating gut microbiota to inhibit LPS-induced TLR4/NF-κB signaling pathway.
Oridonin promotes endoplasmic reticulum stress via TP53-repressed TCF4 transactivation in colorectal cancer.
Biallelic variants in MAD2L1BP (p31(comet)) cause female infertility characterized by oocyte maturation arrest.
Genetic lineage tracing reveals stellate cells as contributors to myofibroblasts in pancreas and islet fibrosis.
Zhx2 maintains islet β-cell mass and function by transcriptionally regulating Pax6.
Cathepsin K promotes the proliferation of hepatocellular carcinoma cells through induction of SIAH1 ubiquitination and degradation.
Aminosalicylates target GPR35, partly contributing to the prevention of DSS-induced colitis.
ZDHHC2-Mediated AGK Palmitoylation Activates AKT-mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma.
Subconjunctival Administration of Mesenchymal Stem Cells Alleviates Ocular Inflammation in a Murine Model of Corneal Alkali Burn.
Microglia activation mediates circadian rhythm disruption-induced cognitive impairment in mice.
Combination effects of amino acid transporter LAT1 inhibitor nanvuranlat and cytotoxic anticancer drug gemcitabine on pancreatic and biliary tract cancer cells.
Baicalein Suppresses NLRP3 and AIM2 Inflammasome-Mediated Pyroptosis in Macrophages Infected by Mycobacterium tuberculosis via Induced Autophagy.
Rapamycin Inhibits Osteoclastogenesis and Prevents LPS-Induced Alveolar Bone Loss by Oxidative Stress Suppression.
Bioengineered Bacteriophage-Like Nanoparticles as RNAi Therapeutics to Enhance Radiotherapy against Glioblastomas.
Gastroprotective Effects of the Aqueous Extract of Finger Citron Pickled Products against Ethanol-Induced Gastric Damage: In Vitro and In Vivo Studies.
Discovery of a potent inhibitor of chaperone-mediated autophagy that targets the HSC70-LAMP2A interaction in non-small cell lung cancer cells.
Yi-Shen-Xie-Zhuo formula alleviates cisplatin-induced AKI by regulating inflammation and apoptosis via the cGAS/STING pathway.
Antidepressive mechanisms of rhynchophylline in mice with chronic unpredictable stress-induced depression.
Ubiquitination of GRK2 Is Required for the β-Arrestin-Biased Signaling Pathway of Dopamine D2 Receptors to Activate ERK Kinases.
The synbiotic mixture of lactulose and Bacillus coagulans protects intestinal barrier dysfunction and apoptosis in weaned piglets challenged with lipopolysaccharide.
EFFECT OF EXOSOMES DERIVED FROM BONE MARROW MESENCHYMAL STEM CELLS ON PROGRAMMED CELL DEATH IN BLAST-INDUCED LUNG INJURY IN RATS.
MiR-24-3p/Dio3 axis is essential for BDE47 to induce local thyroid hormone disorder and neurotoxicity.
Dexamethasone enhances venetoclax-induced apoptosis in acute myeloid leukemia cells.
CM3-SII polysaccharide obtained from Cordyceps militaris ameliorates hyperlipidemia in heterozygous LDLR-deficient hamsters by modulating gut microbiota and NPC1L1 and PPARα levels.
An O-GlcNAc transferase pathogenic variant linked to intellectual disability affects pluripotent stem cell self-renewal.
Tissue-resident CXCR4(+) macrophage as a poor prognosis signature promotes pancreatic ductal adenocarcinoma progression.
Lymphocyte-Related Immunomodulatory Therapy with Siponimod (BAF-312) Improves Outcomes in Mice with Acute Intracerebral Hemorrhage.
Curcumin preconditioning enhances the neuroprotective effects of olfactory mucosa-derived mesenchymal stem cells on experimental intracerebral hemorrhage.
Peripheral immune cell death in sepsis based on bulk RNA and single-cell RNA sequencing.
The role of TRPV4 in the regulation of retinal ganglion cells apoptosis in rat and mouse.
Natural Oncolysis of Enterovirus 71 in Antitumor Therapy of Colorectal Cancer.
Targeting ACYP1-mediated glycolysis reverses lenvatinib resistance and restricts hepatocellular carcinoma progression.
Intermittent Fasting Alleviates Non-Alcoholic Steatohepatitis by Regulating Bile Acid Metabolism and Promoting Fecal Bile Acid Excretion in High-Fat and High-Cholesterol Diet Fed Mice.
Advanced glycation end products promote the progression of chronic kidney diseases by targeting calpain 6.
MLL4 Regulates the Progression of Non-Small-Cell Lung Cancer by Regulating the PI3K/AKT/SOX2 Axis.
RNA-binding Protein QKI Inhibits Osteogenic Differentiation Via Suppressing Wnt Pathway.
Sevoflurane-induced P300 promotes neuron apoptosis via Sp1/CDK9 pathway.
mGluR5 in hippocampal CA1 pyramidal neurons mediates stress-induced anxiety-like behavior.
Hypoxia-Preconditioned Bone Marrow Mesenchymal Stem Cells Improved Cerebral Collateral Circulation and Stroke Outcome in Mice.
The choleretic role of tauroursodeoxycholic acid exacerbates alpha-naphthylisothiocyanate induced cholestatic liver injury through the FXR/BSEP pathway.
USP13 deubiquitinates and stabilizes cyclin D1 to promote gastric cancer cell cycle progression and cell proliferation.
miR-101-5p suppresses trophoblast cell migration and invasion via modulating the DUSP6-ERK1/2 axis in preeclampsia.
Effect of peroxiredoxin 1 on the regulation of trophoblast function by affecting autophagy and oxidative stress in preeclampsia.
SLC25A22 as a Key Mitochondrial Transporter Against Ferroptosis by Producing Glutathione and Monounsaturated Fatty Acids.
HDAC inhibitor chidamide overcomes drug resistance in chronic myeloid leukemia with the T315i mutation through the Akt-autophagy pathway.
Cathepsin B S-nitrosylation promotes ADAR1-mediated editing of its own mRNA transcript via an ADD1/MATR3 regulatory axis.
Absorbable suture knots on the supraspinatus tendon prevent adverse effects of nonabsorbable suture knots in a rat model.
The deubiquitylating enzyme USP35 restricts regulated cell death to promote survival of renal clear cell carcinoma.
The deubiquitinase USP28 maintains the expression of the transcription factor MYCN and is essential in neuroblastoma cells.
Nutrient-dependent regulation of β-cell proinsulin content.
Palmitic acid-induced ferroptosis via CD36 activates ER stress to break calcium-iron balance in colon cancer cells.
Radiation resistance of cancer cells caused by mitochondrial dysfunction depends on SIRT3-mediated mitophagy.
Pemetrexed induces ROS generation and cellular senescence by attenuating TS-mediated thymidylate metabolism to reverse gefitinib resistance in NSCLC.
RBM25 induces trophoblast epithelial-mesenchymal transition and preeclampsia disorder by enhancing the positive feedback loop between Grhl2 and RBM25.
Neotuberostemonine and tuberostemonine ameliorate pulmonary fibrosis through suppressing TGF-β and SDF-1 secreted by macrophages and fibroblasts via the PI3K-dependent AKT and ERK pathways.
Eucommia lignans alleviate the progression of diabetic nephropathy through mediating the AR/Nrf2/HO-1/AMPK axis in vivo and in vitro.
Membrane-dependent actin polymerization mediated by the Legionella pneumophila effector protein MavH.
Bile duct ligation increased dopamine levels in the cerebral cortex of rats partly due to induction of tyrosine hydroxylase.
Emodin attenuates inflammation and demyelination in experimental autoimmune encephalomyelitis.
Betulinic acid mitigates zearalenone-induced liver injury by ERS/MAPK/Nrf2 signaling pathways in mice.
ACC010, a novel BRD4 inhibitor, synergized with homoharringtonine in acute myeloid leukemia with FLT3-ITD.
Resveratrol Promotes Gluconeogenesis by Inhibiting SESN2-mTORC2-AKT Pathway in Calf Hepatocytes.
Targeting NAD metabolism regulates extracellular adenosine levels to improve the cytotoxicity of CD8+ effector T cells in the tumor microenvironment of gastric cancer.
Alpinia oxyphylla Miq. volatile oil ameliorates depressive behaviors and inhibits neuroinflammation in CUMS-exposed mice by inhibiting the TLR4-medicated MyD88/NF-κB signaling pathway.
rTMS treatment for abrogating intracerebral hemorrhage-induced brain parenchymal metabolite clearance dysfunction in male mice by regulating intracranial lymphatic drainage.
Suramin ameliorates osteoarthritis by acting on the Nrf2/HO-1 and NF-κB signaling pathways in chondrocytes and promoting M2 polarization in macrophages.
Ergolide covalently binds NLRP3 and inhibits NLRP3 inflammasome-mediated pyroptosis.
Stromal cell-derived small extracellular vesicles enhance radioresistance of prostate cancer cells via interleukin-8-induced autophagy.
COLEC10 Induces Endoplasmic Reticulum Stress by Occupying GRP78 and Inhibits Hepatocellular Carcinoma.
Targeting macrophagic PIM-1 alleviates osteoarthritis by inhibiting NLRP3 inflammasome activation via suppressing mitochondrial ROS/Cl(-) efflux signaling pathway.
Synergistic Effect of Treatment with Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus and Lipopolysaccharide on the Inflammatory Response of Porcine Pulmonary Microvascular Endothelial Cells.
Abnormal Expression of Prolyl Oligopeptidase (POP) and Its Catalytic Products Ac-SDKP Contributes to the Ovarian Fibrosis Change in Polycystic Ovary Syndrome (PCOS) Mice.
Gasdermin D licenses MHCII induction to maintain food tolerance in small intestine.
Microglial-to-neuronal CCR5 signaling regulates autophagy in neurodegeneration.
Alphavirus-induced transcriptional and translational shutoffs play major roles in blocking the formation of stress granules.
SFRP1 Expression is Inversely Associated With Metastasis Formation in Canine Mammary Tumours.
CircRNA-02191 regulating unsaturated fatty acid synthesis by adsorbing miR-145 to enhance CD36 expression in bovine mammary gland.
Exosomes from tannic acid-stimulated macrophages accelerate wound healing through miR-221-3p mediated fibroblasts migration by targeting CDKN1b.
Long non-coding RNA PVT1 regulates atherosclerosis progression via the microRNA-106b-5p/ACSL4 axis.
FBXL4 ubiquitin ligase deficiency promotes mitophagy by elevating NIX levels.
circACTA2 inhibits NLRP3 inflammasome-mediated inflammation via interacting with NF-κB in vascular smooth muscle cells.
Single-cell transcriptomics reveals intestinal cell heterogeneity and identifies Ep300 as a potential therapeutic target in mice with acute liver failure.
αKG-driven RNA polymerase II transcription of cyclin D1 licenses malic enzyme 2 to promote cell-cycle progression.
Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2.
Astrocytic α4-containing nAChR signaling in the hippocampus governs the formation of temporal association memory.
SIRT3 ameliorates diabetes-associated cognitive dysfunction via regulating mitochondria-associated ER membranes.
Iron induces B cell pyroptosis through Tom20-Bax-caspase-gasdermin E signaling to promote inflammation post-spinal cord injury.
LILRB2/PirB mediates macrophage recruitment in fibrogenesis of nonalcoholic steatohepatitis.
Dephosphorylation of Six2Y129 protects tyrosine hydroxylase-positive cells in SNpc by regulating TEA domain 1 expression.
ZIC2 induces pro-tumor macrophage polarization in nasopharyngeal carcinoma by activating the JUNB/MCSF axis.
Novel Protein C6ORF120 Promotes Apoptosis through Mitochondria-dependent Pathway in CD4 (+)T Lymphocytes.
HnRNP A1 Suppresses the Odontogenic Differentiation and the Inclusion of RUNX2 Exon 5 of Dental Mesenchymal Cells.
Combined surface functionalization of MSC membrane and PDA inhibits neurotoxicity induced by Fe(3)O(4) in mice based on apoptosis and autophagy through the ASK1/JNK signaling pathway.
Transcriptional analysis of the expression and prognostic value of lipid droplet-localized proteins in hepatocellular carcinoma.
Structures of p53/BCL-2 complex suggest a mechanism for p53 to antagonize BCL-2 activity.
Selective activation of AKAP150/TRPV1 in ventrolateral periaqueductal gray GABAergic neurons facilitates conditioned place aversion in male mice.
COPS3 inhibition promotes cell proliferation blockage and anoikis via regulating PFKFB3 in osteosarcoma cancer cells.
Proteomic analysis reveals the mechanisms of the astaxanthin suppressed foam cell formation.
An animal model induced by bilateral cavernous nerve crushing mimics post-radical prostatectomy erectile dysfunction in old rats.
Resveratrol plays an anti-fibrotic and anti-autophagy role by stimulating miR-192-5p expression in urethral fibrosis.
N-Acetylaspartate Drives Oligodendroglial Differentiation via Histone Deacetylase Activation.
JMJD8 regulates neuropathic pain by affecting spinal cord astrocyte differentiation.
Identification of residues critical for the extension of Munc18-1 domain 3a.
Fetal factors disrupt placental and maternal iron homeostasis in murine β-thalassemia.
Activation of the IKK2-NFκB pathway in VSMCs inhibits calcified vascular stiffness in CKD by reducing the secretion of calcifying extracellular vesicles.
CXCR4-Targeted Necrosis-Inducing Peptidomimetic for Treating Breast Cancer.
Embryonic Exposure to UV-328 Impairs the Cell Cycle in Zebrafish (Danio rerio) by Inhibiting the p38 MAPK/p53/Gadd45a Signaling Pathway.
Protective Effect of Water-Soluble Acacetin Prodrug on APAP-Induced Acute Liver Injury Is Associated with Upregulation of PPARγ and Alleviation of ER Stress.
Lysophosphatidic acid is associated with oocyte maturation by enhancing autophagy via PI3K-AKT-mTOR signaling pathway in granulosa cells.
Antiandrogen treatment induces stromal cell reprogramming to promote castration resistance in prostate cancer.
A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy.
γ-Bungarotoxin impairs the vascular endothelial barrier function by inhibiting integrin α5.
Periplocin inhibits hepatocellular carcinoma progression and reduces the recruitment of MDSCs through AKT/NF-κB pathway.
Lysine crotonylation of SERCA2a correlates to cardiac dysfunction and arrhythmia in Sirt1 cardiac-specific knockout mice.
Angelica sinensis aboveground part polysaccharide and its metabolite 5-MT ameliorate colitis via modulating gut microbiota and TLR4/MyD88/NF-κB pathway.
An enzyme-instructed self-assembly system induces tumor acidosis via sequential-dual effect for cancer selective therapy.
Integrating network pharmacology and experimental verification to explore the pharmacological mechanisms of asparagus against polycystic ovary syndrome.
KLF6 alleviates hepatic ischemia-reperfusion injury by inhibiting autophagy.
Heme oxygenase-1 protects against PM2.5 induced endothelial dysfunction through inhibition of HIF1α.
Direct administration of mesenchymal stem cell-derived mitochondria improves cardiac function after infarction via ameliorating endothelial senescence.
Tanshinone functions as a coenzyme that confers gain of function of NQO1 to suppress ferroptosis.
Gomphrena globosa L. extract alleviates carbon tetrachoride-induced liver injury in mice by activating antioxidant signaling pathways and promoting autophagy.
Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.
LncRNA LINC00534 regulates cell proliferation and migration via the miR-494-3p/PTEN axis in HTR-8/SVneo cells.
VASN promotes colorectal cancer progression by activating the YAP/TAZ and AKT signaling pathways via YAP.
6-Methoxydihydrosanguinarine induces apoptosis and autophagy in breast cancer MCF-7 cells by accumulating ROS to suppress the PI3K/AKT/mTOR signaling pathway.
Neuroprotective effect of meglumine cyclic adenylate against ischemia/reperfusion injury via STAT3-Ser727 phosphorylation.
N(6)-Methyladenosine-modified lncRNA LINREP promotes Glioblastoma progression by recruiting the PTBP1/HuR complex.
Bud31-mediated alternative splicing is required for spermatogonial stem cell self-renewal and differentiation.
FAAH served a key membrane-anchoring and stabilizing role for NLRP3 protein independently of the endocannabinoid system.
Quantitative reactive cysteinome profiling reveals a functional link between ferroptosis and proteasome-mediated degradation.
Remodeling of imbalanced extracellular matrix homeostasis for reversal of pancreatic fibrosis.
Dexmedetomidine attenuates airway inflammation and oxidative stress in asthma via the Nrf2 signaling pathway.
Metabolomic analysis and pharmacological validation of the cerebral protective effect of 3,4‑dihydroxybenzaldehyde on cerebral ischemia‑reperfusion injury.
Chloride intracellular channel 1 promotes esophageal squamous cell carcinoma proliferation via mTOR signalling.
FXR1 promotes proliferation, invasion and migration of hepatocellular carcinoma in vitro and in vivo.
RBM24 inhibits the translation of SARS-CoV-2 polyproteins by targeting the 5'-untranslated region.
Upregulation of PIK3IP1 monitors the anti-cancer activity of PI3Kα inhibitors in gastric cancer cells.
Southern rice black-streaked dwarf virus induces incomplete autophagy for persistence in gut epithelial cells of its vector insect.
c-kit(+)VEGFR-2(+) Mesenchymal Stem Cells Differentiate into Cardiovascular Cells and Repair Infarcted Myocardium after Transplantation.
Exosomal microRNA-4535 of Melanoma Stem Cells Promotes Metastasis by Inhibiting Autophagy Pathway.
Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine.
T-cell immunoglobulin- and mucin-domain-containing molecule-4 maintains adipose tissue homeostasis by orchestrating M2 macrophage polarization via nuclear factor kappa B pathway.
Exosomal miR-543 derived from umbilical cord mesenchymal stem cells ameliorates endometrial fibrosis in intrauterine adhesion via downregulating N-cadherin.
Flavonoids dimers from the fruits of Psoralea corylifolia and their cytotoxicity against MCF-7 cells.
Downregulation of CBX7 induced by EZH2 upregulates FGFR3 expression to reduce sensitivity to cisplatin in bladder cancer.
Amyloid β oligomers disrupt piriform cortical output via a serotonergic pathway.
Banoxantrone Coordinated Metal-Organic Framework for Photoacoustic Imaging-Guided High Intensity Focused Ultrasound Therapy.
Methotrexate and Triptolide regulate Notch signaling pathway by targeting the Nedd4-Numb axis.
IL-33/ST2 axis promotes remodeling of the extracellular matrix and drives protective microglial responses in the mouse model of perioperative neurocognitive disorders.
Identification and characterization of novel carboxyl ester lipase gene variants in patients with different subtypes of diabetes.
Alantolactone induces concurrent apoptosis and GSDME-dependent pyroptosis of anaplastic thyroid cancer through ROS mitochondria-dependent caspase pathway.
Phosphoglycerate mutase 5 initiates inflammation in acute kidney injury by triggering mitochondrial DNA release by dephosphorylating the pro-apoptotic protein Bax.
Sclareol ameliorates liver injury by inhibiting nuclear factor-kappa B/NOD-like receptor protein 3-mediated inflammation and lipid metabolism disorder in diabetic mice.
Boswellic acid coated zinc nanoparticles attenuate NF-κB-mediated inflammation in DSS-induced ulcerative colitis in rats.
CD27-Expressing Xenoantigen-Expanded Human Regulatory T Cells Are Efficient in Suppressing Xenogeneic Immune Response.
BDNF-TrkB signaling pathway-mediated microglial activation induces neuronal KCC2 downregulation contributing to dynamic allodynia following spared nerve injury.
Study on the treatment of postmenopausal osteoporosis with quercetin in Liuwei Dihuang Pill based on network pharmacology.
iTRAQ-based Proteomic Analysis Unveils ACSL4 as a Novel Potential Regulator of Human Endometrial Receptivity.
Virulence factors and mechanisms of paediatric pneumonia caused by Enterococcus faecalis.
The Mechanosensitive Ion Channel PIEZO1 in Intestinal Epithelial Cells Mediates Inflammation through the NOD-Like Receptor 3 Pathway in Crohn's Disease.
A Mulberry Diels-Alder-Type Adduct, Kuwanon M, Triggers Apoptosis and Paraptosis of Lung Cancer Cells through Inducing Endoplasmic Reticulum Stress.
PRPF19 Limits Porcine Epidemic Diarrhea Virus Replication through Targeting and Degrading Viral Capsid Protein.
SLC7A14 imports GABA to lysosomes and impairs hepatic insulin sensitivity via inhibiting mTORC2.
A role of cytoplasmic p53 in the regulation of metabolism shown by bat-mimicking p53 NLS mutant mice.
The deubiquitinase OTUD1 noncanonically suppresses Akt activation through its N-terminal intrinsically disordered region.
Disruption of the Intestinal Mucosal Barrier Induced by High Fructose and Restraint Stress Is Regulated by the Intestinal Microbiota and Microbiota Metabolites.
Jinhua Qinggan granules attenuates acute lung injury by promotion of neutrophil apoptosis and inhibition of TLR4/MyD88/NF-κB pathway.
Alteration in branching morphogenesis via YAP/TAZ in fibroblasts of fetal lungs in an LPS-induced inflammation model.
FTO-dependent m(6)A modification of Plpp3 in circSCMH1-regulated vascular repair and functional recovery following stroke.
LncRNA WDR11-AS1 Promotes Extracellular Matrix Synthesis in Osteoarthritis by Directly Interacting with RNA-Binding Protein PABPC1 to Stabilize SOX9 Expression.
Ketogenic Diet Combined with Moderate Aerobic Exercise Training Ameliorates White Adipose Tissue Mass, Serum Biomarkers, and Hepatic Lipid Metabolism in High-Fat Diet-Induced Obese Mice.
Vacuole Membrane Protein 1 (VMP1) Restricts NLRP3 Inflammasome Activation by Modulating SERCA Activity and Autophagy.
Identification of the Acid-Sensitive Site Critical for Chloral Hydrate (CH) Activation of the Proton-Activated Chloride Channel.
Activation of NLRP3 inflammasome in lung epithelial cells triggers radiation-induced lung injury.
Membrane-dependent actin polymerization mediated by the Legionella pneumophila effector protein MavH.
LIPUS accelerates bone regeneration via HDAC6-mediated ciliogenesis.
TRIM15 forms a regulatory loop with the AKT/FOXO1 axis and LASP1 to modulate the sensitivity of HCC cells to TKIs.
PHB2 promotes colorectal cancer cell proliferation and tumorigenesis through NDUFS1-mediated oxidative phosphorylation.
Photobiomodulation promotes spinal cord injury repair by inhibiting macrophage polarization through lncRNA TUG1-miR-1192/TLR3 axis.
The role of atypical MAP kinase 4 in the host interaction with Cryptosporidium parvum.
Long noncoding RNA uc007nnj.1 mediates neuronal death induced by retinal ischemia/reperfusion in mice via the miR-155-5p/Tle4 axis.
Structural basis of bacterial effector protein azurin targeting tumor suppressor p53 and inhibiting its ubiquitination.
The natural flavone acacetin protects against high-fat diet-induced lipid accumulation in the liver via the endoplasmic reticulum stress/ferroptosis pathway.
Knockdown of PKMYT1 is associated with autophagy inhibition and apoptosis induction and suppresses tumor progression in hepatocellular carcinoma.
Novel insights into the mediating roles of cluster of differentiation 36 in transmembrane transport and tissue partition of per- and polyfluoroalkyl substances in mice.
Inhibition of cGAS ameliorates acute lung injury triggered by zinc oxide nanoparticles.
BAP31 regulates the expression of ICAM-1/VCAM-1 via MyD88/NF-κB pathway in acute lung injury mice model.
The U2AF65/circNCAPG/RREB1 feedback loop promotes malignant phenotypes of glioma stem cells through activating the TGF-β pathway.
Flavivirus prM interacts with MDA5 and MAVS to inhibit RLR antiviral signaling.
Betulinaldehyde exhibits effective anti-tumor effects in A549 cells by regulating intracellular autophagy.
Discovery of rafoxanide as a novel agent for the treatment of non-small cell lung cancer.
Crizotinib Nanomicelles Synergize with Chemotherapy through Inducing Proteasomal Degradation of Mutp53 Proteins.
PFC@O(2) Targets HIF-1α to Reverse the Immunosuppressive TME in OSCC.
Dioscin reduced chemoresistance for colon cancer and analysis of sensitizing targets.
Ablation of AQP5 gene in mice leads to olfactory dysfunction caused by hyposecretion of Bowman's gland.
Toxicity of polystyrene nanoparticles for mouse ovary and cultured human granulosa cells.
A Prevascularized Sinus Tract on the Liver Surface for Islet Transplantation.
M2 macrophages with inflammation tropism facilitate cementoblast mineralization.
Luteolin improves vasoconstriction function and survival of septic mice via AMPK/NF-κB pathway.
Triptonide inhibits growth and metastasis in HCC by suppressing EGFR/PI3K/AKT signaling.
CRISPR-Cas9-Mediated NPC1 Gene Deletion Enhances HEK 293 T Cell Adhesion by Regulating E-Cadherin.
Moderate-Intensity Treadmill Exercise Promotes mTOR-Dependent Motor Cortical Neurotrophic Factor Expression and Functional Recovery in a Murine Model of Crush Spinal Cord Injury (SCI).
Disrupted in renal carcinoma 2 (DIRC2/SLC49A4) is an H(+)-driven lysosomal pyridoxine exporter.
The role of Sirt3-induced autophagy in renal structural damage caused by periodontitis in rats.
Cul5 mediates taurine-stimulated mTOR mRNA expression and proliferation of mouse mammary epithelial cells.
Fc receptor-like 1 (FCRL1) is a novel biomarker for prognosis and a possible therapeutic target in diffuse large B-cell lymphoma.
Extracellular acidosis restricts one-carbon metabolism and preserves T cell stemness.
POU Domain Class 2 Transcription Factor 2 Inhibits Ferroptosis in Cerebral Ischemia Reperfusion Injury by Activating Sestrin2.
MiR-29c Inhibits TNF-α-Induced ROS Production and Apoptosis in Mouse Hippocampal HT22 Cell Line.
Anti-inflammatory effects of extracellular vesicles from Morchella on LPS-stimulated RAW264.7 cells via the ROS-mediated p38 MAPK signaling pathway.
PKMYT1 inhibits lung adenocarcinoma progression by abrogating AKT1 activity.
Oligosaccharide Blocks PAR1 (Proteinase-Activated Receptor 1)-PAR4-Mediated Platelet Activation by Binding to Thrombin Exosite II and Impairs Thrombosis.
miR-34b-3p Inhibition of eIF4E Causes Post-stroke Depression in Adult Mice.
The cytotoxicity of zinc oxide nanoparticles to 3D brain organoids results from excessive intracellular zinc ions and defective autophagy.
STAT3/Mitophagy Axis Coordinates Macrophage NLRP3 Inflammasome Activation and Inflammatory Bone Loss.
Bone marrow mesenchymal stem cells repair hexavalent chromium-induced testicular injury by regulating autophagy and ferroptosis mediated by the AKT/mTOR pathway in rats.
Ubiquitin-specific protease 24 promotes EV71 infection by restricting K63-linked polyubiquitination of TBK1.
Paeoniflorin-6'-O-benzene sulfonate protected the intestinal epithelial barrier by restoring the inhibitory effect of GRK2 and β-arrestin 2 on ERK1/2-NF-κB.
N(6)-methyladenosine-modified USP13 induces pro-survival autophagy and imatinib resistance via regulating the stabilization of autophagy-related protein 5 in gastrointestinal stromal tumors.
Forced activation of dystrophin transcription by CRISPR/dCas9 reduced arrhythmia susceptibility via restoring membrane Nav1.5 distribution.
TIPE1 promotes liver regeneration by enhancing ROS-FoxO1 axis mediated autophagy.
Landscape of pathogenic mutations in premature ovarian insufficiency.
KIAA1199 promotes oxaliplatin resistance and epithelial mesenchymal transition of colorectal cancer via protein O-GlcNAcylation.
Pirfenidone suppressed triple-negative breast cancer metastasis by inhibiting the activity of the TGF-β/SMAD pathway.
Role of SUMOylation of STAT1 in tubular epithelial‑mesenchymal transition induced by high glucose.
Mechanism of autophagy mediated by IGF-1 signaling pathway in the neurotoxicity of lead in pubertal rats.
YTHDF2 orchestrates tumor-associated macrophage reprogramming and controls antitumor immunity through CD8(+) T cells.
Mitochondrial targeting half-sandwich iridium(III) and ruthenium(II) dppf complexes and in vitro anticancer assay.
Inositol polyphosphates-regulated polyubiquitination of PHR1 by NLA E3 ligase during phosphate starvation response in Arabidopsis.
Effects of substrate topography on the regulation of human fibroblasts and capsule formation via modulating macrophage polarization.
Barrier-penetrating liposome targeted delivery of basic fibroblast growth factor for spinal cord injury repair.
LncRNA NR2F1-AS1 was involved in azacitidine resistance of THP-1 cells by targeting IGF1 with miR-483-3p.
A biomaterial-based therapy using a sodium hyaluronate/bioglass composite hydrogel for the treatment of oral submucous fibrosis.
Hyperbaric oxygen enhanced the chemotherapy of mitochondrial targeting molecule IR-780 in bladder cancer.
Costunolide covalently targets NACHT domain of NLRP3 to inhibit inflammasome activation and alleviate NLRP3-driven inflammatory diseases.
Identification of miR-30c-5p as a tumor suppressor by targeting the m(6) A reader HNRNPA2B1 in ovarian cancer.
Macrophage migration inhibitory factor (MIF) inhibitor iSO-1 promotes staphylococcal protein A-induced osteogenic differentiation by inhibiting NF-κB signaling pathway.
Transcriptome analysis highlights the role of ferroptosis in palmitic acid-induced endothelial dysfunction.
Sestrin2 contributes to BRAF inhibitor resistance via reducing redox vulnerability of melanoma cells.
Manipulation of PD-L1 Endosomal Trafficking Promotes Anticancer Immunity.
Low temperature exposure inhibits proliferation and induces apoptosis of bovine subcutaneous preadipocytes via p38 MAPK/JNK activation.
The Prognostic Value and the Oncogenic and Immunological Roles of Vacuolar Protein Sorting Associated Protein 26 A in Pancreatic Adenocarcinoma.
Morphometric analysis of the size-adjusted linear dimensions of the skull landmarks revealed craniofacial dysmorphology in Mid1-cKO mice.
Protective Effect of 20(S)-Protopanaxadiol on D-Gal-Induced Cognitively Impaired Mice Based on Its Target Protein Brain-type Creatine Kinase.
Ginsenoside Rg3 Ameliorates DSS-Induced Colitis by Inhibiting NLRP3 Inflammasome Activation and Regulating Microbial Homeostasis.
Viral Hemorrhagic Septicemia Virus Activates Integrated Stress Response Pathway and Induces Stress Granules to Regulate Virus Replication.
Myristic acid as a checkpoint to regulate STING-dependent autophagy and interferon responses by promoting N-myristoylation.
Methyltransferase-like 3 aggravates endoplasmic reticulum stress in preeclampsia by targeting TMBIM6 in YTHDF2-dependent manner.
Chromatin remodeler BRM is a key mediator of leucine-stimulated mTOR gene transcription in mouse mammary epithelial cells.
Ang-(1-7)/MasR axis promotes functional recovery after spinal cord injury by regulating microglia/macrophage polarization.
Ant-Neointimal Formation Effects of SLC6A6 in Preventing Vascular Smooth Muscle Cell Proliferation and Migration via Wnt/β-Catenin Signaling.
Microglia PKM2 Mediates Neuroinflammation and Neuron Loss in Mice Epilepsy through the Astrocyte C3-Neuron C3R Signaling Pathway.
Cofilin promotes tau pathology in Alzheimer's disease.
E2F1 inhibits cellular senescence and promotes oxaliplatin resistance in colorectal cancer.
Naringenin is a Potential Immunomodulator for Inhibiting Liver Fibrosis by Inhibiting the cGAS-STING Pathway.
Lactobacillus johnsonii L531 Ameliorates Salmonella enterica Serovar Typhimurium Diarrhea by Modulating Iron Homeostasis and Oxidative Stress via the IRP2 Pathway.
Peroxiredoxin-6 Released by Astrocytes Contributes to Neuroapoptosis During Ischemia.
Cyanidin-3-O-glucoside and protocatechuic acid alleviate heat stress-induced testicular damage.
Synergistic effects of L-theanine and epigallocatechin gallate in alleviating ovalbumin allergy by regulating intestinal immunity through inhibition of mast cell degranulation.
TIM-4 orchestrates mitochondrial homeostasis to promote lung cancer progression via ANXA2/PI3K/AKT/OPA1 axis.
Enterococcus faecalis promotes the progression of colorectal cancer via its metabolite: biliverdin.
Optimization of Primary Human Bronchial Epithelial 3D Cell Culture with Donor-Matched Fibroblasts and Comparison of Two Different Culture Media.
Circular RNA METTL9 contributes to neuroinflammation following traumatic brain injury by complexing with astrocytic SND1.
Nanodrug rescues liver fibrosis via synergistic therapy with H(2)O(2) depletion and Saikosaponin b1 sustained release.
RGS12 represses oral squamous cell carcinoma by driving M1 polarization of tumor-associated macrophages via controlling ciliary MYCBP2/KIF2A signaling.
Thiram-induced hyperglycemia causes tibial dyschondroplasia by triggering aberrant ECM remodeling via the gut-pancreas axis in broiler chickens.
Disorders in the gut and liver are involved in depression contagion between isosexual post-stroke depression mice and the healthy cohabitors.
Hexokinase 2-mediated glycolysis supports inflammatory responses to Porphyromonas gingivalis in gingival fibroblasts.
CMTM3 protects the gastric epithelial cells from apoptosis and promotes IL-8 by stabilizing NEMO during Helicobacter pylori infection.
Exosomal lncRNA HOTAIR induces PDL1(+) B cells to impede anti-tumor immunity in colorectal cancer.
Qingre Huazhuo Jiangsuan Decoction promotes autophagy by inhibiting PI3K/AKT/mTOR signaling pathway to relieve acute gouty arthritis.
Macrophage Migration Inhibitory Factor Promotes Expression of Matrix Metalloproteinases 1 and 3 in Spinal Cord Astrocytes following Gecko Tail Amputation.
Melanin-like polydopamine nanoparticles mediating anti-inflammatory and rescuing synaptic loss for inflammatory depression therapy.
mTOR inhibitor, gemcitabine and PD-L1 antibody blockade combination therapy suppresses pancreatic cancer progression via metabolic reprogramming and immune microenvironment remodeling in Trp53(flox/+)LSL-Kras(G12D/+)Pdx-1-Cre murine models.
GRAMD1/ASTER-mediated cholesterol transport promotes Smoothened cholesterylation at the endoplasmic reticulum.
HERC2 promotes inflammation-driven cancer stemness and immune evasion in hepatocellular carcinoma by activating STAT3 pathway.
Clinical Implications of a New DDX58 Pathogenic Variant That Causes Lupus Nephritis due to RIG-I Hyperactivation.
Molecular weight-dependent hyaluronic acid permeability and tight junction modulation in human buccal TR146 cell monolayers.
BMF-AS1/BMF Promotes Diabetic Vascular Calcification and Aging both In Vitro and In Vivo.
MiR-224-5p inhibits osteoblast differentiation and impairs bone formation by targeting Runx2 and Sp7.
Phenylalanine diminishes M1 macrophage inflammation.
JSI-124 inhibits cell proliferation and tumor growth by inducing autophagy and apoptosis in murine malignant mesothelioma.
Guilu-Erxian-Glue alleviates Tripterygium wilfordii polyglycoside-induced oligoasthenospermia in rats by resisting ferroptosis via the Keap1/Nrf2/GPX4 signaling pathway.
Integrating network pharmacology and experimental validation to decipher the mechanism of the Chinese herbal prescription modified Shen-Yan-Fang-Shuai formula in treating diabetic nephropathy.
Transcriptomic analysis reveals the regulatory mechanism underlying the indirubin-mediated amelioration of dextran sulfate sodium-induced colitis in mice.
NDRG1 promotes endothelial dysfunction and hypoxia-induced pulmonary hypertension by targeting TAF15.
Glioblastoma cellular MAP4K1 facilitates tumor growth and disrupts T effector cell infiltration.
Hypoxia dissociates HDAC6/FOXO1 complex and aggregates them into nucleus to regulate autophagy and osteogenic differentiation.
Role of GPX4 inhibition-mediated ferroptosis in the chemoresistance of ovarian cancer to Taxol in vitro.
TRPV4-mediated Ca(2+) deregulation causes mitochondrial dysfunction via the AKT/α-synuclein pathway in dopaminergic neurons.
Targeting TRIM24 promotes neuroblastoma differentiation and decreases tumorigenicity via LSD1/CoREST complex.
LncRNA H19-EZH2 interaction promotes liver fibrosis via reprogramming H3K27me3 profiles.
Dual network analysis of transcriptome data for discovery of new therapeutic targets in non-small cell lung cancer.
Integrating network pharmacology and experimental models to examine the mechanisms of corosolic acid in preventing hepatocellular carcinoma progression through activation PERK-eIF2a-ATF4 signaling.
Hyperhomocysteinemia lowers serum testosterone concentration via impairing testosterone production in Leydig cells.
Design, synthesis, and evaluation of novel benzoylhydrazone derivatives as Nur77 modulators with potent antitumor activity against hepatocellular carcinoma.
Molecular mechanisms in the miR-33a/LPPR4 pathway regulating unsaturated fatty acid synthesis in bovine mammary epithelial cells.
Mannose antagonizes GSDME-mediated pyroptosis through AMPK activated by metabolite GlcNAc-6P.
Functional analysis of two SLC9A6 frameshift variants in lymphoblastoid cells from patients with Christianson syndrome.
Photobiomodulation reduces neuropathic pain after spinal cord injury by downregulating CXCL10 expression.
PP2Ac knockdown attenuates lipotoxicity‑induced pancreatic β‑cell dysfunction and apoptosis.
FAM107A as a tumor suppressor in esophageal squamous carcinoma inhibits growth and metastasis.
Blue light photobiomodulation induced apoptosis by increasing ROS level and regulating SOCS3 and PTEN/PI3K/AKT pathway in osteosarcoma cells.
Insulin-like growth factor 2 mRNA-binding protein 2 is a therapeutic target in ovarian cancer.
Integrated analysis of murine cornea identifies JAK/STAT signaling pathway upregulated specifically in female Vitamin A Deficient mice.
HD-sEVs in bovine follicular fluid regulate granulosa cell apoptosis and estradiol secretion through the autophagy pathway.
Integrated NLRP3, AIM2, NLRC4, Pyrin inflammasome activation and assembly drive PANoptosis.
Inhibition of USP1 ameliorates hypertensive nephropathy through regulating oxidative stress and ferroptosis: A precise treatment via SJB3-019A nanodelivery.
ENO1 promotes liver carcinogenesis through YAP1-dependent arachidonic acid metabolism.
Scribble promotes fibrosis-dependent mechanisms of hepatocarcinogenesis by p53/PUMA-mediated glycolysis.
Ceftazidime reduces cellular Skp2 to promote type-I interferon activity.
CBX4 promotes antitumor immunity by suppressing Pdcd1 expression in T cells.
The synthetic oleanane triterpenoid CDDO-2P-Im binds GRP78/BiP to induce unfolded protein response-mediated apoptosis in myeloma.
Trigonelline inhibits tubular epithelial-mesenchymal transformation in diabetic kidney disease via targeting Smad7.
Cell-in-Cell-Mediated Entosis Reveals a Progressive Mechanism in Pancreatic Cancer.
Propionate promotes gluconeogenesis by regulating mechanistic target of rapamycin (mTOR) pathway in calf hepatocytes.
The expression of Nramp1 modulates the uptake of Mycobacterium tuberculosis by macrophages through alternating inflammatory responses.
Staphylococcus aureus planktonic but not biofilm environment induces an IFN-β macrophage immune response via the STING/IRF3 pathway.
Oligomeric Aβ25-35 induces the tyrosine phosphorylation of PSD-95 by SrcPTKs in rat hippocampal CA1 subfield.
Berberine ameliorates renal interstitial inflammation and fibrosis in mice with unilateral ureteral obstruction.
The novel CDK9 inhibitor, XPW1, alone and in combination with BRD4 inhibitor JQ1, for the treatment of clear cell renal cell carcinoma.
Assessment of intestinal status in MPL(W515L) mutant myeloproliferative neoplasms mice model.
Identification of TMEM53 as a novel SADS-CoV restriction factor that targets viral RNA-dependent RNA polymerase.
SARS-CoV-2 Omicron subvariants exhibit distinct fusogenicity, but similar sensitivity, to pan-CoV fusion inhibitors.
NSUN2-mediated M(5)c methylation of IRF3 mRNA negatively regulates type I interferon responses during various viral infections.
PROS1, a clinical prognostic biomarker and tumor suppressor, is associated with immune cell infiltration in breast cancer: A bioinformatics analysis combined with experimental verification.
Umbelliferone attenuates cisplatin-induced acute kidney injury by inhibiting oxidative stress and inflammation via NRF2.
Inducible nitric oxide synthase accelerates nonalcoholic fatty liver disease progression by regulating macrophage autophagy.
Inhibition of inflammation and infiltration of M2 macrophages in NSCLC through the ATF3/CSF1 axis: Role of miR-27a-3p.
Probiotic-fermented Qushi decoction alleviates reserpine-induced spleen deficiency syndrome by regulating spleen function and gut microbiota dysbiosis.
Bone Marrow-Derived GCA(+) Immune Cells Drive Alzheimer's Disease Progression.
Prolonged sleep deprivation induces a cytokine-storm-like syndrome in mammals.
The Human Placental Amniotic Membrane Mesenchymal-Stromal-Cell-Derived Conditioned Medium Inhibits Growth and Promotes Apoptosis of Human Cholangiocarcinoma Cells In Vitro and In Vivo by Suppressing IL-6/JAK2/STAT3 Signaling.
HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance.
The Role of Cellular Senescence in Cyclophosphamide-Induced Primary Ovarian Insufficiency.
DHA and EPA Alleviate Epileptic Depression in PTZ-Treated Young Mice Model by Inhibiting Neuroinflammation through Regulating Microglial M2 Polarization and Improving Mitochondrial Metabolism.
Study on the mechanism of Orthosiphon aristatus (Blume) Miq. in the treatment of hyperuricemia by microbiome combined with metabonomics.
Pro-inflammatory Cytokines Promote the Occurrence and Development of Colitis-associated Colorectal Cancer by Inhibiting miR-615-5p.
Design, synthesis, and biological evaluation of novel 4,4'-bipyridine derivatives acting as CDK9-Cyclin T1 protein-protein interaction inhibitors against triple-negative breast cancer.
Mechanistic insights into the homo-dimerization of HOIL-1L and SHARPIN.
Super-enhancer-associated EEPD1 facilitates EMT-mediated metastasis by regulating the PI3K/AKT/mTOR pathway in gastric cancer.
Soyasaponin I alleviates hypertensive intracerebral hemorrhage by inhibiting the renin-angiotensin-aldosterone system.
Exopolysaccharide from Weissella confusa J4-1 inhibits colorectal cancer via induction of cell cycle arrest.
An injectable and light curable hyaluronic acid composite gel with anti-biofilm, anti-inflammatory and pro-healing characteristics for accelerating infected wound healing.
Astragaloside IV enhances the sensitivity of breast cancer stem cells to paclitaxel by inhibiting stemness.
IGF2BP1 enhances the stability of SIK2 mRNA through m(6)A modification to promote non-small cell lung cancer progression.
Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy.
RTKN2 knockdown alleviates the malignancy of breast cancer cells by regulating the Wnt/β-catenin pathway.
DPP4 Regulates the Th17/IL-17 Axis and Accelerates Epithelial Mesenchymal Transition to Promote Ovalbumin-Induced Asthma in Female C57BL/6J Mice.
Biochemical Toxicological Study of Insulin Overdose in Rats: A Forensic Perspective.
Circulating small extracellular vesicles microRNAs plus CA-125 for treatment stratification in advanced ovarian cancer.
Phosphorylated Adapter RNA Export Protein Is Methylated at Lys 381 by an Methyltransferase-like 21C (METTL21C).
Schistosome egg-derived extracellular vesicles deliver Sja-miR-71a inhibits host macrophage and neutrophil extracellular traps via targeting Sema4D.
Choroid plexus mast cells drive tumor-associated hydrocephalus.
Identification and validation of key biomarkers associated with macrophages in nonalcoholic fatty liver disease based on hdWGCNA and machine learning.
BACH1 controls hepatic insulin signaling and glucose homeostasis in mice.
Nobiletin Ameliorates Hepatic Lipid Deposition, Oxidative Stress, and Inflammation by Mechanisms That Involve the Nrf2/NF-κB Axis in Nonalcoholic Fatty Liver Disease.
Vidofludimus inhibits porcine reproductive and respiratory syndrome virus infection by targeting dihydroorotate dehydrogenase.
Hedgehog-Gli1-derived exosomal circ-0011536 mediates peripheral neural remodeling in pancreatic cancer by modulating the miR-451a/VGF axis.
Insights into the ISG15 transfer cascade by the UBE1L activating enzyme.
The nonstructural protein 1 of respiratory syncytial virus hijacks host mitophagy as a novel mitophagy receptor to evade the type I IFN response in HEp-2 cells.
Gss deficiency causes age-related fertility impairment via ROS-triggered ferroptosis in the testes of mice.
ER Stress-Perturbed Intracellular Protein O-GlcNAcylation Aggravates Podocyte Injury in Diabetes Nephropathy.
The HSP40 family chaperone isoform DNAJB6b prevents neuronal cells from tau aggregation.
Fluorinated Cell-Penetrating Peptide for Co-Delivering siHIF-1α and Sorafenib to Enhance In Vitro Anti-Tumor Efficacy.
Glycyrrhetinic acid attenuates endoplasmic reticulum stress-induced hepatocyte apoptosis via CHOP/DR5/Caspase 8 pathway in cholestasis.
GPR146 regulates pulmonary vascular remodeling by promoting pulmonary artery smooth muscle cell proliferation through 5-lipoxygenase.
Glutathione-responsive PROTAC for targeted degradation of ERα in breast cancer cells.
Targeting AKT induced Ferroptosis through FTO/YTHDF2-dependent GPX4 m6A methylation up-regulating and degradating in colorectal cancer.
Adoptive transfer of immature dendritic cells with high HO-1 expression delays the onset of T1DM in NOD mice.
A Study on the Pharmacological Effects and Mechanism of Rhodojaponin III in Rheumatoid Arthritis.
Identification of ANXA3 as a biomarker associated with pyroptosis in ischemic stroke.
Autophagy is involved in degradation of AQP1 in response to an acute decrement in tonicity.
Foxp3-mediated blockage of ryanodine receptor 2 underlies contact-based suppression by regulatory T cells.
IL20RB signaling enhances stemness and chemotherapy resistance in pancreatic cancer.
Cyclosporine A alleviates colitis by inhibiting the formation of neutrophil extracellular traps via the regulating pentose phosphate pathway.
Alleviation of ischemia-reperfusion induced renal injury by chemically modified SOD2 mRNA delivered via lipid nanoparticles.
Cytomegalovirus-vectored COVID-19 vaccines elicit neutralizing antibodies against the SARS-CoV-2 Omicron variant (BA.2) in mice.
NLRP3 inflammasome-mediated pyroptosis involvement in cadmium exposure-induced cognitive deficits via the Sirt3-mtROS axis.
Inhibition of the lncRNA 585189 prevents podocyte injury and mitochondria dysfunction by promoting hnRNP A1 and SIRT1 in diabetic nephropathy.
Restoring System xc- activity by xCT overexpression inhibited neuronal ferroptosis and improved neurological deficits after experimental subarachnoid hemorrhage.
CRISPR screening identifies the deubiquitylase ATXN3 as a PD-L1-positive regulator for tumor immune evasion.
LY6E is a pan-coronavirus restriction factor in the respiratory tract.
Exosomal PPARγ derived from macrophages suppresses LPS-induced peritonitis by negative regulation of CD14/TLR4 axis.
Retrotransposons hijack alt-EJ for DNA replication and eccDNA biogenesis.
Scutellarin Acts via MAPKs Pathway to Promote M2 Polarization of Microglial Cells.
The therapeutic effect of tanshinone IIA in mouse astrocytes after treatment with Angiostrongylus cantonensis fifth-stage larval excretory-secretory products.
Aquaporin 1 is a prognostic marker and inhibits tumour progression through downregulation of Snail expression in intrahepatic cholangiocarcinoma.
The G allele of SNP rs3922 reduces the binding affinity between IGF2BP3 and CXCR5 correlating with a lower antibody production.
Dipyridamole enhances the anti-cancer ability of aspirin against colorectal cancer by inducing apoptosis in an unfolded protein response-dependent manner.
Glutamine metabolic microenvironment drives M2 macrophage polarization to mediate trastuzumab resistance in HER2-positive gastric cancer.
Cell Cycle-Related FAM64A Could be Activated by TGF-β Signaling to Promote Glioma Progression.
SARS-CoV-2 Nsp8 induces mitophagy by damaging mitochondria.
Dickkopf-1 promotes vascular smooth muscle cell foam cell formation and atherosclerosis development through CYP4A11/SREBP2/ABCA1.
Metal-ion transporter SLC39A8 is required for brain manganese uptake and accumulation.
PTBP1 suppresses porcine epidemic diarrhea virus replication via inducing protein degradation and IFN production.
HIV-1 subtype B Tat enhances NOTCH3 signaling in astrocytes to mediate oxidative stress, inflammatory response, and neuronal apoptosis.
Role of Escin in breast cancer therapy: potential mechanism for inducing ferroptosis and synergistic antitumor activity with cisplatin.
Identification and validation of SOCS1/2/3/4 as potential prognostic biomarkers and correlate with immune infiltration in glioblastoma.
Overexpression of hepatic pescadillo 1 in obesity induces lipid dysregulation by inhibiting autophagy.
ETS1 Ameliorates Hyperoxia-Induced Bronchopulmonary Dysplasia in Mice by Activating Nrf2/HO-1 Mediated Ferroptosis.
Profilin1 Regulates Trophoblast Invasion and Macrophage Differentiation.
Contrasting effects of filamin A and B proteins in modulating filovirus entry.
N protein of PEDV plays chess game with host proteins by selective autophagy.
Mesenchymal Stem Cell-Derived Exosomal miR-150-3p Affects Intracerebral Hemorrhage By Regulating TRAF6/NF-κB Axis, Gut Microbiota and Metabolism.
Death-associated protein kinase 1 is associated with cognitive dysfunction in major depressive disorder.
Potential targets and mechanisms of photobiomodulation for spinal cord injury.
High SNRPA1 expression leads to poor prognosis in patients with lung adenocarcinoma.
Schwann cell-derived amphiregulin enhances nerve regeneration via supporting the proliferation and migration of Schwann cells and the elongation of axons.
1,8-Cineole ameliorates diabetic retinopathy by inhibiting retinal pigment epithelium ferroptosis via PPAR-γ/TXNIP pathways.
AF9 sustains glycolysis in colorectal cancer via H3K9ac-mediated PCK2 and FBP1 transcription.
PRSS2 regulates EMT and metastasis via MMP-9 in gastric cancer.
Ficolin A knockout alleviates sepsis-induced severe lung injury in mice by restoring gut Akkermansia to inhibit S100A4/STAT3 pathway.
Astragaloside IV protects LO2 cells from oxidative damage caused by radiation-induced bystander effect through Akt/Nrf2 pathway.
ROS Scavenging Nanozyme Modulates Immunosuppression for Sensitized Cancer Immunotherapy.
Inhibition of VEGFR2 and EGFR signaling cooperatively suppresses the proliferation of oral squamous cell carcinoma.
YAP/STAT3 inhibited CD8(+) T cells activity in the breast cancer immune microenvironment by inducing M2 polarization of tumor-associated macrophages.
Angiopoietin-like 4 induces head and neck squamous cell carcinoma cell migration through the NRP1/ABL1/PXN pathway.
Curcumin enhances elvitegravir concentration and alleviates oxidative stress and inflammatory response.
Mitochondrial carrier 1 (MTCH1) governs ferroptosis by triggering the FoxO1-GPX4 axis-mediated retrograde signaling in cervical cancer cells.
Hesperidin may improve depressive symptoms by binding NLRP3 and influencing the pyroptosis pathway in a rat model.
SQLE promotes pancreatic cancer growth by attenuating ER stress and activating lipid rafts-regulated Src/PI3K/Akt signaling pathway.
Identification of NOX4 as a New Biomarker in Hepatocellular Carcinoma and Its Effect on Sorafenib Therapy.
Ficolin B secreted by alveolar macrophage exosomes exacerbates bleomycin-induced lung injury via ferroptosis through the cGAS-STING signaling pathway.
Tissue pleiotropic effect of biotin and prebiotic supplementation in established obesity.
Optimized allotopic expression of mitochondrial ND6 transgene restored complex I and apoptosis deficiencies caused by LHON-linked ND6 14484T > C mutation.
MicroRNA-144-3p protects against chemotherapy-induced apoptosis of ovarian granulosa cells and activation of primordial follicles by targeting MAP3K9.
MATR3-antisense LINE1 RNA meshwork scaffolds higher-order chromatin organization.
Hedgehog receptors exert immune-surveillance roles in the epidermis across species.
SLC38A5 aggravates DC-mediated psoriasiform skin inflammation via potentiating lysosomal acidification.
Sox10 escalates vascular inflammation by mediating vascular smooth muscle cell transdifferentiation and pyroptosis in neointimal hyperplasia.
A p53/LINC00324 positive feedback loop suppresses tumor growth by counteracting SET-mediated transcriptional repression.
The non-redundant functions of PIWI family proteins in gametogenesis in golden hamsters.
Inhibition of cancer-type amino acid transporter LAT1 suppresses B16-F10 melanoma metastasis in mouse models.
A Compared Study of Eicosapentaenoic Acid and Docosahexaenoic Acid in Improving Seizure-Induced Cognitive Deficiency in a Pentylenetetrazol-Kindling Young Mice Model.
Convergent activation of Ca(2+) permeability in two-pore channel 2 through distinct molecular routes.
Flt3 Activation Mitigates Mitochondrial Fragmentation and Heart Dysfunction through Rebalanced L-OPA1 Processing by Hindering the Interaction between Acetylated p53 and PHB2 in Cardiac Remodeling.
DpdtpA, A Multi-metal Ion Chelator, Attenuates Tau Phosphorylation and Microglial Inflammatory Response via Regulating the PI3K/AKT/GSK-3β Signal Pathways.
Differential effects of PGAM5 knockout on high fat high fructose diet and methionine choline-deficient diet induced non-alcoholic steatohepatitis (NASH) in mice.
[VDAC1 participates in house dust mite-induced asthmatic airway inflammation in mice by inducing ferroptosis of airway epithelial cells].
Inosine enhances tumor mitochondrial respiration by inducing Rag GTPases and nascent protein synthesis under nutrient starvation.
Mutational burden of XPNPEP3 leads to defects in mitochondrial complex I and cilia in NPHPL1.
IRP1 mediated ferroptosis reverses temozolomide resistance in glioblastoma via affecting LCN2/FPN1 signaling axis depended on NFKB2.
A defective mechanosensing pathway affects fibroblast-to-myofibroblast transition in the old male mouse heart.
Warburg effect enhanced by AKR1B10 promotes acquired resistance to pemetrexed in lung cancer-derived brain metastasis.
Design and discovery of new selective and potent VEGF receptor 2 tyrosine kinase inhibitors.
PGAM5 deacetylation mediated by SIRT2 facilitates lipid metabolism and liver cancer proliferation.
FAAP100 is required for the resolution of transcription-replication conflicts in primordial germ cells.
Estradiol mitigates stress-induced cardiac injury and inflammation by downregulating ADAM17 via the GPER-1/PI3K signaling pathway.
Structural and biochemical insights into the molecular mechanism of TRPT1 for nucleic acid ADP-ribosylation.
Intermittent fasting activates macrophage migration inhibitory factor and alleviates high-fat diet-induced nonalcoholic fatty liver disease.
Simiao San alleviates hyperuricemia and kidney inflammation by inhibiting NLRP3 inflammasome and JAK2/STAT3 signaling in hyperuricemia mice.
Marein reduces lipid levels via modulating the PI3K/AKT/mTOR pathway to induce lipophagy.
Nicotinamide Riboside Improves Stemness of Human Adipose-Derived Stem Cells and Inhibits Terminal Adipocyte Differentiation.
Subchronic Arsenite Exposure Induced Atrophy and Erythropoietin Sensitivity Reduction in Skeletal Muscle Were Relevant to Declined Serum Melatonin Levels in Middle-Aged Rats.
Repetitive Transcranial Magnetic Stimulation Improves Depression-like Behavior in Rats by Promoting Neural Stem Cell Proliferation and Differentiation.
Schisandrin B induces HepG2 cells pyroptosis by activating NK cells mediated anti-tumor immunity.
Low-dose graphene oxide promotes tumor cells proliferation by activating PI3K-AKT-mTOR signaling via cellular membrane protein integrin αV.
Mucin2 regulated by Ho1/p38/IL-10 axis plays a protective role in polystyrene nanoplastics-mediated intestinal toxicity.
miR-342-5p promotes vascular smooth muscle cell phenotypic transition through a negative-feedback regulation of Notch signaling via targeting FOXO3.
Repairing gastric ulcer with hyaluronic acid/extracellular matrix composite through promoting M2-type polarization of macrophages.
A terrified-sound stress causes cognitive impairment in female mice by impairing neuronal plasticity.
PARP16-Mediated Stabilization of Amyloid Precursor Protein mRNA Exacerbates Alzheimer's Disease Pathogenesis.
Houpo paiqi mixture promotes intestinal motility in constipated rats by modulating gut microbiota and activating 5-HT-cAMP-PKA signal pathway.
Weizmannia coagulans JA845 improves atherosclerosis induced by vitamin D3 and high-fat diet in rats through modulating lipid metabolism, oxidative stress, and endothelial vascular injury.
The effect of PINK1/Parkin pathway on glucose homeostasis imbalance induced by tacrolimus in mouse livers.
Mitochondrial division inhibitor (mdivi-1) inhibits proliferation and epithelial-mesenchymal transition via the NF-κB pathway in thyroid cancer cells.
Therapeutic role of Artemether in the prevention of hepatic steatosis through miR-34a-5p/PPARα pathway.
Amnion-derived serum amyloid A1 participates in sterile inflammation of fetal membranes at parturition.
Osmoadaptive GLP-1R signalling in hypothalamic neurones inhibits antidiuretic hormone synthesis and release.
Holothuria leucospilota Polysaccharides Improve Immunity and the Gut Microbiota in Cyclophosphamide-Treated Immunosuppressed Mice.
LncRNA CFAR promotes cardiac fibrosis via the miR-449a-5p/LOXL3/mTOR axis.
SNORD60 promotes the tumorigenesis and progression of endometrial cancer through binding PIK3CA and regulating PI3K/AKT/mTOR signaling pathway.
FUT2-dependent fucosylation of HYOU1 protects intestinal stem cells against inflammatory injury by regulating unfolded protein response.
Sensitive and quantitative in vivo analysis of PD-L1 using magnetic particle imaging and imaging-guided immunotherapy.
PGAM4 silencing inhibited glycolysis and chemoresistance to temozolomide in glioma cells.
Hederagenin Suppresses Inflammation and Cartilage Degradation to Ameliorate the Progression of Osteoarthritis: An In vivo and In vitro Study.
Reciprocal FGF19-GLI2 signaling induces epithelial-to-mesenchymal transition to promote lung squamous cell carcinoma metastasis.
Activation of TRPV1 receptor facilitates myelin repair following demyelination via the regulation of microglial function.
NONO regulates B-cell development and B-cell receptor signaling.
P4HA2-mediated HIF-1α stabilization promotes erdafitinib-resistance in FGFR3-alteration bladder cancer.
Perilla frutescens L. alleviates trimethylamine N-oxide-induced apoptosis in the renal tubule by regulating ASK1-JNK phosphorylation.
Reshaping the Endogenous Electric Field to Boost Wound Repair via Electrogenerative Dressing.
Influence of cyclin D1 splicing variants expression on breast cancer chemoresistance via CDK4/CyclinD1-pRB-E2F1 pathway.
Kaempferol promotes melanogenesis and reduces oxidative stress in PIG1 normal human skin melanocytes.
Tax1 binding protein 3 regulates osteogenic and adipogenic differentiation through inactivating Wnt/β-catenin signalling.
Knockdown of the long non‑coding RNA MALAT1 ameliorates TNF‑α‑mediated endothelial cell pyroptosis via the miR‑30c‑5p/Cx43 axis.
Hydroxysafflor Yellow A Exerts Neuroprotective Effect by Reducing Aβ Toxicity Through Inhibiting Endoplasmic Reticulum Stress in Oxygen-Glucose Deprivation/Reperfusion Cell Model.
LPS inhibits TRIM65 expression in macrophages and C57BL/6J mouse by activating the ERK1/2 signaling pathway.
Low expression of SEMA4D as a potential predictive molecular marker of poor survival in patients with melanoma combined with liver cancer.
PSKH1 affects proliferation and invasion of osteosarcoma cells via the p38/MAPK signaling pathway.
MiR-133a/CD47 axis is a novel prognostic biomarker to promote triple negative breast cancer progression.
CircHGS enhances the progression of bladder cancer by regulating the miR-513a-5p/VEGFC axis and activating the AKT/mTOR signaling pathway.
Dimethyl fumarate protects against hepatic ischemia-reperfusion injury by alleviating ferroptosis via the NRF2/SLC7A11/HO-1 axis.
ADAMTS12 promotes migration and epithelial-mesenchymal transition and predicts poor prognosis for pancreatic cancer.
Lenvatinib inhibited HCC cell migration and invasion through regulating the transcription and ubiquitination of UHRF1 and DNMT1.
Oncogenic FLT3 internal tandem duplication activates E2F1 to regulate purine metabolism in acute myeloid leukaemia.
Selenoprotein Gene mRNA Expression Evaluation During Renal Ischemia-Reperfusion Injury in Rats and Ebselen Intervention Effects.
HTR2A agonists play a therapeutic role by restricting ILC2 activation in papain-induced lung inflammation.
Selenoprotein K enhances STING oligomerization to facilitate antiviral response.
FOXP3+ macrophage represses acute ischemic stroke-induced neural inflammation.
Necroptosis plays a crucial role in the exacerbation of retinal injury after blunt ocular trauma.
Identification and functional analysis of three novel genetic variants resulting in premature termination codons in three unrelated patients with hereditary antithrombin deficiency.
EGFR-TNFR1 pathway in endothelial cell facilitates acute lung injury by NF-κB/MAPK-mediated inflammation and RIP3-dependent necroptosis.
ARID1B blocks methionine-stimulated mTOR activation to inhibit milk fat and protein synthesis in and proliferation of mouse mammary epithelial cells.
Acinetobacter baumannii outer membrane protein A induces autophagy in bone marrow-derived dendritic cells involving the PI3K/mTOR pathway.
Engineered Extracellular Vesicle-Delivered CRISPR/CasRx as a Novel RNA Editing Tool.
Wei-Tong-Xin exerts anti-inflammatory effects through TLR4-mediated macrophages M1/M2 polarization and affects GLP-1 secretion.
ZSWIM1 Promotes the Proliferation and Metastasis of Lung Adenocarcinoma Cells through the STK38/MEKK2/ERK1/2 Axis.
Integrated network pharmacology and experimental verification to explore the molecular mechanism of Jingxin Zhidong formula for treating Tic disorder.
Identification of hub genes and pathways in lung metastatic colorectal cancer.
RNF20 is required for male fertility through regulation of H2B ubiquitination in the Sertoli cells.
Goliath induces inflammation in obese mice by linking fatty acid β-oxidation to glycolysis.
Ligation to Scavenging Strategy Enables On-Demand Termination of Targeted Protein Degradation.
Lateral septum adenosine A(2A) receptors control stress-induced depressive-like behaviors via signaling to the hypothalamus and habenula.
Characterization of dominant-negative growth hormone receptor variants reveals a potential therapeutic target for short stature.
Heat-Killed Lacticaseibacillus paracasei Repairs Lipopolysaccharide-Induced Intestinal Epithelial Barrier Damage via MLCK/MLC Pathway Activation.
Aqueous-soluble components of sporoderm-removed Ganoderma lucidum spore powder promote ferroptosis in oral squamous cell carcinoma.
Donkey Oil-Based Ketogenic Diet Prevents Tumor Progression by Regulating Intratumor Inflammation, Metastasis and Angiogenesis in CT26 Tumor-Bearing Mice.
The outer mitochondrial membrane protein TMEM11 demarcates spatially restricted BNIP3/BNIP3L-mediated mitophagy.
Knockdown of the SELENOK gene induces ferroptosis in cervical cancer cells.
Caffeine can alleviate non-alcoholic fatty liver disease by augmenting LDLR expression via targeting EGFR.
Upregulation of carbonic anhydrase 1 beneficial for depressive disorder.
Identification of glutamyl-prolyl-tRNA synthetase as a new therapeutic target in hepatocellular carcinoma via a novel bioinformatic approach.
Dual role of PID1 in regulating apoptosis induced by distinct anticancer-agents through AKT/Raf-1-dependent pathway in hepatocellular carcinoma.
N(6)-methyladenosine reader IGF2BP3 as a prognostic Biomarker contribute to malignant progression of glioma.
Acinous cell AR42J-derived exosome miR125b-5p promotes acute pancreatitis exacerbation by inhibiting M2 macrophage polarization via PI3K/AKT signaling pathway.
MAVS-Based Reporter Systems for Real-Time Imaging of EV71 Infection and Antiviral Testing.
The complement inhibitor CD59 is required for GABAergic synaptic transmission in the dentate gyrus.
Synergistic effect of constituent drugs of Baibutang on improving Yin-deficiency pulmonary fibrosis in rats.
Progerinin, an Inhibitor of Progerin, Alleviates Cardiac Abnormalities in a Model Mouse of Hutchinson-Gilford Progeria Syndrome.
Sleeve gastrectomy decreased hepatic lipid accumulation by inducing autophagy via AMPK/mTOR pathway.
In situ isolation of nuclei or nuclear proteins from adherent cells: a simple, effective method with less cytoplasmic contamination.
Human Cytomegalovirus UL23 Antagonizes the Antiviral Effect of Interferon-γ by Restraining the Expression of Specific IFN-Stimulated Genes.
Protective Effect of Lonicera japonica on PM(2.5)-Induced Pulmonary Damage in BALB/c Mice via the TGF-β and NF-κB Pathway.
NLRP3 Plays a Key Role in Antihelminth Immunity in the Enteral and Parenteral Stages of Trichinella spiralis-Infected Mice.
p53 protects against alcoholic fatty liver disease via ALDH2 inhibition.
Phosphorylation and stabilization of EZH2 by DCAF1/VprBP trigger aberrant gene silencing in colon cancer.
Vimar/RAP1GDS1 promotes acceleration of brain aging after flies and mice reach middle age.
Mitoglitazone ameliorates renal ischemia/reperfusion injury by inhibiting ferroptosis via targeting mitoNEET.
cGAS Mediates Inflammation by Polarizing Macrophages to M1 Phenotype via the mTORC1 Pathway.
High-cholesterol diet promotes depression- and anxiety-like behaviors in mice by impact gut microbe and neuroinflammation.
Resveratrol induces proliferation and differentiation of mouse pre-osteoblast MC3T3-E1 by promoting autophagy.
EPC-exosomal miR-26a-5p improves airway remodeling in COPD by inhibiting ferroptosis of bronchial epithelial cells via PTGS2/PGE2 signaling pathway.
Immunophenotyping of Monocyte Migration Markers and Therapeutic Effects of Selenium on IL-6 and IL-1β Cytokine Axes of Blood Mononuclear Cells in Preoperative and Postoperative Coronary Artery Disease Patients.
TIGD1 Function as a Potential Cuproptosis Regulator Following a Novel Cuproptosis-Related Gene Risk Signature in Colorectal Cancer.
Porcine Epidemic Diarrhea Virus Replication in Human Intestinal Cells Reveals Potential Susceptibility to Cross-Species Infection.
Menstrual blood-derived endometrial stem cells alleviate neuroinflammation by modulating M1/M2 polarization in cell and rat Parkinson's disease models.
Excessive serine from the bone marrow microenvironment impairs megakaryopoiesis and thrombopoiesis in Multiple Myeloma.
Xiaoyaosan ameliorates depressive-like behavior and susceptibility to glucose intolerance in rat: involvement of LepR-STAT3/PI3K pathway in hypothalamic arcuate nucleus.
Hepatic G Protein-Coupled Receptor 180 Deficiency Ameliorates High Fat Diet-Induced Lipid Accumulation via the Gi-PKA-SREBP Pathway.
Deregulation of ER-mitochondria contact formation and mitochondrial calcium homeostasis mediated by VDAC in fragile X syndrome.
Palmitoyl transferases act as novel drug targets for pancreatic cancer.
ME2 Promotes Hepatocellular Carcinoma Cell Migration through Pyruvate.
Exosomal circCLIP1 regulates PM(2.5)-induced airway obstruction via targeting SEPT10 in vitro.
Subchronic Microcystin-LR Aggravates Colorectal Inflammatory Response and Barrier Disruption via Raf/ERK Signaling Pathway in Obese Mice.
Identification of FEZ2 as a potential oncogene in pancreatic ductal adenocarcinoma.
Role of TRPV1 ion channel in cervical squamous cell carcinoma genesis.
Identification of amino acid residues in the MT-loop of MT1-MMP critical for its ability to cleave low-density lipoprotein receptor.
Structural Characterization and Anti-breast Cancer Activity in vitro of a Novel Polysaccharide From Cymbopogon citratus.
Sodium-glucose cotransporter-2 inhibitor alleviated atrial remodeling in STZ-induced diabetic rats by targeting TLR4 pathway.
The Protective Effect of Sulforaphane on Dextran Sulfate Sodium-Induced Colitis Depends on Gut Microbial and Nrf2-Related Mechanism.
(-)-Epicatechin Provides Neuroprotection in Sodium Iodate-Induced Retinal Degeneration.
Isoliquiritin Ameliorates Cisplatin-Induced Renal Proximal Tubular Cell Injury by Antagonizing Apoptosis, Oxidative Stress and Inflammation.
Momordica. charantia-Derived Extracellular Vesicles-Like Nanovesicles Protect Cardiomyocytes Against Radiation Injury via Attenuating DNA Damage and Mitochondria Dysfunction.
Ornithine α-Ketoglutarate Alleviates Inflammation via Regulating Ileal Mucosa Microbiota and Metabolites in Enterotoxigenic Escherichia coli-Infected Pigs.
The Mechanism of Lipopolysaccharide Escaping the Intestinal Barrier in Megalobrama amblycephala Fed a High-Fat Diet.
Berberine Ameliorates Inflammation in Acute Lung Injury via NF-κB/Nlrp3 Signaling Pathway.
Effects of Excessive Activation of N-methyl-D-aspartic Acid Receptors in Neonatal Cardiac Mitochondrial Dysfunction Induced by Intrauterine Hypoxia.
Metabolomic Profile Reveals That Ceramide Metabolic Disturbance Plays an Important Role in Thoracic Aortic Dissection.
Selective Cleavage at CCA Ends and Anticodon Loops of tRNAs by Stress-Induced RNases.
Expression of the Immune Checkpoint Protein VISTA Is Differentially Regulated by the TGF-β1 - Smad3 Signaling Pathway in Rapidly Proliferating Human Cells and T Lymphocytes.
Melatonin Engineered Adipose-Derived Biomimetic Nanovesicles Regulate Mitochondrial Functions and Promote Myocardial Repair in Myocardial Infarction.
Dishevelled-Associated Activator of Morphogenesis 2 (DAAM2) Predicts the Immuno-Hot Phenotype in Pancreatic Adenocarcinoma.
Differential Expression Profile of microRNAs and Tight Junction in the Lung Tissues of Rat With Mitomycin-C-Induced Pulmonary Veno-Occlusive Disease.
Molecular and Cellular Response of the Myocardium (H9C2 Cells) Towards Hypoxia and HIF-1α Inhibition.
Cryptotanshinone attenuates LPS-induced acute lung injury by regulating metabolic reprogramming of macrophage.
Exosomes derived from M2 macrophages induce angiogenesis to promote wound healing.
Metabolic Reprogramming of Microglia Enhances Proinflammatory Cytokine Release through EphA2/p38 MAPK Pathway in Alzheimer's Disease.
Probiotic Bifidobacterium breve Prevents Memory Impairment Through the Reduction of Both Amyloid-β Production and Microglia Activation in APP Knock-In Mouse.
Administration of miR-195 Inhibitor Enhances Memory Function Through Improving Synaptic Degradation and Mitochondrial Dysfunction of the Hippocampal Neurons in SAMP8 Mice.
Spatial Training Attenuates Long-Term Alzheimer's Disease-Related Pathogenic Processes in APP/PS1 Mice.
3D-Printed β-Tricalcium Phosphate Scaffolds Promote Osteogenic Differentiation of Bone Marrow-Deprived Mesenchymal Stem Cells in an N6-methyladenosine-Dependent Manner.
Antitumor Effects of Astaxanthin on Esophageal Squamous Cell Carcinoma by up-Regulation of PPARγ.
Lactobacillus acidophilus ATCC 4356 Exopolysaccharides Suppresses Mediators of Inflammation through the Inhibition of TLR2/STAT-3/P38-MAPK Pathway in DEN-Induced Hepatocarcinogenesis in Rats.
LincRNA-p21 Upregulates Nuclear Orphan Receptor Nr4a2 and Aggravates Myocardial Ischemia/Reperfusion Injury via Targeting MiR-466i-5p.
Astragaloside IV - mediated endothelial progenitor cell exosomes promote autophagy and inhibit apoptosis in hyperglycemic damaged endothelial cells via miR-21/PTEN axis.
Neferine Suppresses Experimental Colitis-Associated Colorectal Cancer by Inhibition of NF-[Formula: see text]B p65 and STAT3.
Protective Effect of Ginsenosides from Stems and Leaves of Panax ginseng against Scopolamine-Induced Memory Damage via Multiple Molecular Mechanisms.
Effects of Capsaicin on the Hypoglycemic Regulation of Metformin and Gut Microbiota Profiles in Type 2 Diabetic Rats.
Proanthocyanidin oligomers extract from hawthorn mediates cell cycle arrest, apoptosis, and lysosome vacuolation on HCT116 cells.
Study on the Protective Effect of Schizandrin B against Acetaminophen-Induced Cytotoxicity in Human Hepatocyte.
RING-Finger Protein 6 promotes Drug Resistance in Retinoblastoma via JAK2/STAT3 Signaling Pathway.
Sufentanil Alleviates Sepsis-Induced Myocardial Injury and Stress Response in Rats through the ERK/GSK-3β Signaling Axis.
lncRNA IGF2-AS Regulates Nucleotide Metabolism by Mediating HMGA1 to Promote Pyroptosis of Endothelial Progenitor Cells in Sepsis Patients.
A Network Pharmacology Approach for Uncovering the Antitumor Effects and Potential Mechanisms of the Sijunzi Decoction for the Treatment of Gastric Cancer.
Qingfei Tongluo Formula Mitigates Mycoplasma pneumoniae Infection via the PERK Signaling Pathway.
Betaine Inhibits NLRP3 Inflammasome Hyperactivation and Regulates Microglial M1/M2 Phenotypic Differentiation, Thereby Attenuating Lipopolysaccharide-Induced Depression-Like Behavior.
Hippocampal Mitochondrial Abnormalities Induced the Dendritic Complexity Reduction and Cognitive Decline in a Rat Model of Spinal Cord Injury.
HSPB8 Overexpression Ameliorates Cognitive Impairment in Diabetic Mice via Inhibiting NLRP3 Inflammation Activation.
Electroacupuncture Preconditioning Alleviates Lipopolysaccharides-Induced Acute Lung Injury by Downregulating LC3-II/I and Beclin 1 Expression.
Sequential Treatment with Activin and Hepatocyte Growth Factor Induces FOXM1 to Promote Colorectal Cancer Liver Metastasis.
Cell-Dependent Pathogenic Roles of Filamin B in Different Skeletal Malformations.
Activation of LRP1 Ameliorates Cerebral Ischemia/Reperfusion Injury and Cognitive Decline by Suppressing Neuroinflammation and Oxidative Stress through TXNIP/NLRP3 Signaling Pathway in Mice.
Long Noncoding RNA ENSG00000254693 Promotes Diabetic Kidney Disease via Interacting with HuR.
Thioredoxin-Interacting Protein (TXNIP) Knockdown Protects against Sepsis-Induced Brain Injury and Cognitive Decline in Mice by Suppressing Oxidative Stress and Neuroinflammation.
Nr2f2 Overexpression Aggravates Ferroptosis and Mitochondrial Dysfunction by Regulating the PGC-1α Signaling in Diabetes-Induced Heart Failure Mice.
MiR-205-5p Functions as a Tumor Suppressor in Gastric Cancer Cells through Downregulating FAM84B.
Downregulated XBP-1 Rescues Cerebral Ischemia/Reperfusion Injury-Induced Pyroptosis via the NLRP3/Caspase-1/GSDMD Axis.
miR-138-5p Inhibits the Growth and Invasion of Glioma Cells by Regulating WEE1.
Hepatoblastoma: Derived Exosomal LncRNA NEAT1 Induces BMSCs Differentiation into Tumor-Supporting Myofibroblasts via Modulating the miR-132/MMP9 Axis.
Celastrol Protects against Cerebral Ischemia/Reperfusion Injury in Mice by Inhibiting Glycolysis through Targeting HIF-1α/PDK1 Axis.
Protective Effect of Photobiomodulation against Hydrogen Peroxide-Induced Oxidative Damage by Promoting Autophagy through Inhibition of PI3K/AKT/mTOR Pathway in MC3T3-E1 Cells.
Preventive Effects of Ilex Cornuta Aqueous Extract on High-Fat Diet-Induced Fatty Liver of Mice.
Metabolism-Related Gene TXNRD1 Regulates Inflammation and Oxidative Stress Induced by Cigarette Smoke through the Nrf2/HO-1 Pathway in the Small Airway Epithelium.
Molecular Mechanisms Underlying the Effects of Bimin Kang Mixture on Allergic Rhinitis: Network Pharmacology and RNA Sequencing Analysis.
Pygo1 Regulates the Behavior of Human Non-Small-Cell Lung Cancer via the Wnt/β-Catenin Pathway.
Targeting Ferroptosis Attenuates Inflammation, Fibrosis, and Mast Cell Activation in Chronic Prostatitis.
Electroacupuncture at Zusanli Alleviates Sepsis by Regulating the TLR4-MyD88-NF-Kappa B Pathway and Diversity of Intestinal Flora.
Effects of Electroacupuncture at Different Acupoints on Functional Dyspepsia Rats.
miR-127-5p Targets JAM3 to Regulate Ferroptosis, Proliferation, and Metastasis in Malignant Meningioma Cells.
Controlled Hemorrhage Sensitizes Angiotensin II-Elicited Hypertension through Activation of the Brain Renin-Angiotensin System Independently of Endoplasmic Reticulum Stress.
The Gut Microbiota Dysbiosis in Preeclampsia Contributed to Trophoblast Cell Proliferation, Invasion, and Migration via lncRNA BC030099/NF-κB Pathway.
Correlation Analysis of Umbilical Cord Blood Metabolic Phenotype and Inflammation in Patients with Gestational Diabetes Mellitus Complicated with Overweight and Obesity.
Expression of POT1-AS1 in GC Tissue, Its Effect on Biological Behavior of Gastric Cancer, and Its Significance on Prognosis of Gastric Cancer.
Baicalin Alleviates Thrombin-Induced Inflammation in Vascular Smooth Muscle Cells.
The Traditional Chinese Medicine Formula FTZ Protects against Cardiac Fibrosis by Suppressing the TGFβ1-Smad2/3 Pathway.
Xuesaitong Combined with Dexmedetomidine Improves Cerebral Ischemia-Reperfusion Injury in Rats by Activating Keap1/Nrf2 Signaling and Mitophagy in Hippocampal Tissue.
Quantitative Proteomics Analysis Expands the Roles of Lysine β-Hydroxybutyrylation Pathway in Response to Environmental β-Hydroxybutyrate.
Cepharanthine Attenuates Early Brain Injury after Subarachnoid Hemorrhage in Mice via Inhibiting 15-Lipoxygenase-1-Mediated Microglia and Endothelial Cell Ferroptosis.
Silencing ATF3 Might Delay TBHP-Induced Intervertebral Disc Degeneration by Repressing NPC Ferroptosis, Apoptosis, and ECM Degradation.
Inhibition of KCTD10 Affects Diabetic Retinopathy Progression by Reducing VEGF and Affecting Angiogenesis.
Preparation and Biocompatibility of Core-Shell Microspheres for Sequential, Sustained Release of BMP-2 and VEGF.
Acidic Tumor Microenvironment Promotes Pancreatic Cancer through miR-451a/MEF2D Axis.
The lncRNA KIF9-AS1 Accelerates Hepatocellular Carcinoma Growth by Recruiting DNMT1 to Promote RAI2 DNA Methylation.
Lycopene Improves Bone Quality and Regulates AGE/RAGE/NF-кB Signaling Pathway in High-Fat Diet-Induced Obese Mice.
Identification of RPS7 as the Biomarker of Ferroptosis in Acute Kidney Injury.
Prognostic Lnc-S100B-2 Affects Cell Apoptosis and Microenvironment of Colorectal Cancer through MLLT10 Signaling.
Theaflavin-3,3'-Digallate Inhibits Erastin-Induced Chondrocytes Ferroptosis via the Nrf2/GPX4 Signaling Pathway in Osteoarthritis.
miR-328-5p Induces Human Intervertebral Disc Degeneration by Targeting WWP2.
Transcutaneous Electrical Acupoint Stimulation Ameliorates Cognitive Function through PINK1/Parkin Mediated Mitophagy in VD Rats.
Artemisinin and Its Derivate Alleviate Pulmonary Hypertension and Vasoconstriction in Rodent Models.
Therapy-resistant and -sensitive lncRNAs, SNHG1 and UBL7-AS1 promote glioblastoma cell proliferation.
Rhein Ameliorates Cognitive Impairment in an APP/PS1 Transgenic Mouse Model of Alzheimer's Disease by Relieving Oxidative Stress through Activating the SIRT1/PGC-1α Pathway.
The Pretreatment of Xiaoqinglong Decoction Alleviates Inflammation and Oxidative Damage and Up-Regulates Angiotensin-Converting Enzyme 2 in Lipopolysaccharide-Induced Septic Acute Lung Injury Rats.
Overexpression of PTPRZ1 Regulates p120/β-Catenin Phosphorylation to Promote Carcinogenesis of Oral Submucous Fibrosis.
High-Calcium Microenvironment during the Development of Kidney Calculi Can Promote Phenotypic Transformation of NRK-52E Cells by Inhibiting the Expression of Stromal Interaction Molecule-1.
Mitochondrial Targeted Antioxidant SKQ1 Ameliorates Acute Kidney Injury by Inhibiting Ferroptosis.
Oleoylethanolamide Alleviates Hepatic Ischemia-Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress-Associated Apoptosis.
Isoschaftoside Reverses Nonalcoholic Fatty Liver Disease via Activating Autophagy In Vivo and In Vitro.
Sestrin2 Overexpression Ameliorates Endoplasmic Reticulum Stress-Induced Apoptosis via Inhibiting mTOR Pathway in HepG2 Cells.
lncRNA GAS5 Sensitizes Breast Cancer Cells to Ionizing Radiation by Inhibiting DNA Repair.
Hugan Buzure Induces Autophagy and Apoptosis in Hepatocellular Carcinoma by Inhibiting PI3K/Akt/mTOR Signaling Pathway.
Tuftelin 1 Facilitates Hepatocellular Carcinoma Progression through Regulation of Lipogenesis and Focal Adhesion Maturation.
Upregulation of Klotho Aggravates Insulin Resistance in Gestational Diabetes Mellitus Trophoblast Cells.
Ginsenoside Rg1 Reduces Oxidative Stress Via Nrf2 Activation to Regulate Age-Related Mesenchymal Stem Cells Fate Switch Between Osteoblasts and Adipocytes.
Mitochondrial Transplantation Promotes Remyelination and Long-Term Locomotion Recovery following Cerebral Ischemia.
PPARγ Alleviates Sepsis-Induced Liver Injury by Inhibiting Hepatocyte Pyroptosis via Inhibition of the ROS/TXNIP/NLRP3 Signaling Pathway.
Paeoniflorin attenuates monocrotaline-induced pulmonary arterial hypertension in rats by suppressing TAK1-MAPK/NF-κB pathways.
Upregulation of SQLE Contributes to Poor Survival in Head and Neck Squamous Cell Carcinoma.
Quantitative proteomics of HFD-induced fatty liver uncovers novel transcription factors of lipid metabolism.
TDG suppresses the migration and invasion of human colon cancer cells via the DNMT3A/TIMP2 axis.
Mannan-Binding Lectin Deficiency Limits Inflammation-induced Myeloid-Derived Suppressor Cells Expansion via Modulating Tumor Necrosis Factor Alpha-triggered Apoptosis.
Cancer-associated adipocytes promote the invasion and metastasis in breast cancer through LIF/CXCLs positive feedback loop.
Hypoxic pancreatic cancer derived exosomal miR-30b-5p promotes tumor angiogenesis by inhibiting GJA1 expression.
Mir-484 contributes to diminished ovarian reserve by regulating granulosa cell function via YAP1-mediated mitochondrial function and apoptosis.
Lactylation of PKM2 Suppresses Inflammatory Metabolic Adaptation in Pro-inflammatory Macrophages.
P2RY13 Exacerbates Intestinal Inflammation by Damaging the Intestinal Mucosal Barrier via Activating IL-6/STAT3 Pathway.
A Novel ER Stress Mediator TMTC3 Promotes Squamous Cell Carcinoma Progression by Activating GRP78/PERK Signaling Pathway.
The m6A-induced lncRNA CASC8 promotes proliferation and chemoresistance via upregulation of hnRNPL in esophageal squamous cell carcinoma.
Deacetylation of Glutaminase by HDAC4 contributes to Lung Cancer Tumorigenesis.
RASAL2 mediated the enhancement of YAP1/TIAM1 signaling promotes malignant phenotypes of pancreatic ductal adenocarcinoma.
Mechanosensitive Piezo1 is crucial for periosteal stem cell-mediated fracture healing.
Enhanced Intracellular Reactive Oxygen Species by Photodynamic Therapy Effectively Promotes Chemoresistant Cell Death.
Supplementation with dietary omega-3 PUFA mitigates fetal brain inflammation and mitochondrial damage caused by high doses of sodium nitrite in maternal rats.
LncRNA LINC01857 reduces metastasis and angiogenesis in breast cancer cells via regulating miR-2052/CENPQ axis.
Long non-coding RNA NEAT1 promotes angiogenesis in hepatoma carcinoma via the miR-125a-5p/VEGF pathway.
NCOA4-Mediated Ferroptosis in Bronchial Epithelial Cells Promotes Macrophage M2 Polarization in COPD Emphysema.
Study on the Local Anti-Osteoporosis Effect of Polaprezinc-Loaded Antioxidant Electrospun Membrane.
Pseudoephedrine Nanoparticles Alleviate Adriamycin-Induced Reproductive Toxicity Through the GnRhR Signaling Pathway.
Microglial activation in the motor cortex mediated NLRP3-related neuroinflammation and neuronal damage following spinal cord injury.
The Role of Microglia/Macrophages Activation and TLR4/NF-κB/MAPK Pathway in Distraction Spinal Cord Injury-Induced Inflammation.
Ursolic Acid Ameliorates Spinal Cord Injury in Mice by Regulating Gut Microbiota and Metabolic Changes.
MicroRNA-582-5p Contributes to the Maintenance of Neural Stem Cells Through Inhibiting Secretory Protein FAM19A1.
Meningitic Escherichia coli-Induced Interleukin-17A Facilitates Blood-Brain Barrier Disruption via Inhibiting Proteinase 3/Protease-Activated Receptor 2 Axis.
Anomalous Levels of CD47/Signal Regulatory Protein Alpha in the Hippocampus Lead to Excess Microglial Engulfment in Mouse Model of Perioperative Neurocognitive Disorders.
Genetic Inhibition of Plppr5 Aggravates Hypoxic-Ischemie-Induced Cortical Damage and Excitotoxic Phenotype.
Anti-Inflammatory Effects and Molecular Mechanisms of Shenmai Injection in Treating Acute Pancreatitis: Network Pharmacology Analysis and Experimental Verification.
The m6A RNA Modification Quantity and the Prognostic Effect of Reader YTHDC2 in Colorectal Cancer.
Excitatory and Inhibitory Synaptic Imbalance Caused by Brain-Derived Neurotrophic Factor Deficits During Development in a Valproic Acid Mouse Model of Autism.
NF-κB and AP-1 are required for the lipopolysaccharide-induced expression of MCP-1, CXCL1, and Cx43 in cultured rat dorsal spinal cord astrocytes.
FGF15 Protects Septic Mice by Inhibiting Inflammation and Modulating Treg Responses.
Engeletin Alleviates the Inflammation and Apoptosis in Intervertebral Disc Degeneration via Inhibiting the NF-κB and MAPK Pathways.
Chitosan/Sodium Alginate/Velvet Antler Blood Peptides Hydrogel Promotes Diabetic Wound Healing via Regulating Angiogenesis, Inflammatory Response and Skin Flora.
Alpha-Momorcharin Inhibits Proinflammatory Cytokine Expression by M1 Macrophages but Not Anti-Inflammatory Cytokine Expression by M2 Macrophages.
MULT1-Encoding DNA Alleviates Schistosomiasis-Associated Hepatic Fibrosis via Modulating Cellular Immune Response.
miR-17-5p Promotes Glucose Uptake of HTR8/SVneo Trophoblast Cells by Inhibiting TXNIP/NLRP3 Inflammasome Pathway.
Effect of Azelaic Acid on Psoriasis Progression Investigated Based on Phosphatidylinositol 3-Kinase (PI3K)/Protein Kinase B (AKT) Signaling Pathway.
Identification of Biomarkers Related to Regulatory T Cell Infiltration in Oral Squamous Cell Carcinoma Based on Integrated Bioinformatics Analysis.
Mannan-Binding Lectin Regulates the Th17/Treg Axis Through JAK/STAT and TGF-β/SMAD Signaling Against Candida albicans Infection.
Shortening of the KHDRBS1 3'UTR by alternative cleavage and polyadenylation alters miRNA-mediated regulation and promotes gastric cancer progression.
Arsenic exposure increases susceptibility to Ptpn11-induced malignancy in mouse embryonic fibroblasts through mitochondrial hypermetabolism.
TM9SF4 Is a Crucial Regulator of Inflammation and ER Stress in Inflammatory Bowel Disease.
GDF15 negatively regulates RGS16 to impair hepatic lipid metabolism in male mice offspring conceived by in vitro fertilization.
The CEL-HYB1 Hybrid Allele Promotes Digestive Enzyme Misfolding and Pancreatitis in Mice.
Presenilin Deficiency Increases Susceptibility to Oxidative Damage in Fibroblasts.
Role of BDNF/ProBDNF Imbalance in Postoperative Cognitive Dysfunction by Modulating Synaptic Plasticity in Aged Mice.
Identification of Key Genes and FUNCTIONAL Pathway in Radioresistance of Non-Small Cell Lung Cancer.
AKAP9 Upregulation Predicts Unfavorable Prognosis in Pediatric Acute Myeloid Leukemia and Promotes Stemness Properties via the Wnt/β-Catenin Pathway.
Circular RNA circASPM promotes the progression of glioblastoma by acting as a competing endogenous RNA to regulate miR-130b-3p/E2F1 axis.
Targeting HNRNPM Inhibits Cancer Stemness and Enhances Antitumor Immunity in Wnt-activated Hepatocellular Carcinoma.
Loss of SPTBN1 Suppresses Autophagy Via SETD7-mediated YAP Methylation in Hepatocellular Carcinoma Initiation and Development.
Epigenetic modifications inhibit the expression of MARVELD1 and in turn tumorigenesis by regulating the Wnt/β-catenin pathway in pan-cancer.
Akkermansia muciniphila administration exacerbated the development of colitis-associated colorectal cancer in mice.
Temporally integrated transcriptome analysis reveals ASFV pathology and host response dynamics.
Photobiomodulation promotes repair following spinal cord injury by restoring neuronal mitochondrial bioenergetics via AMPK/PGC-1α/TFAM pathway.
Connective tissue disease-related interstitial lung disease is alleviated by tripterine through inhibition of the PI3K/Akt, apoptosis, and TNF-α signalling pathways.
Herpes simplex virus type 2 inhibits TNF-α-induced NF-κB activation through viral protein ICP22-mediated interaction with p65.
MiR-146b-5p/TRAF6 axis is essential for Ginkgo biloba L. extract GBE to attenuate LPS-induced neuroinflammation.
Anti-inflammatory, antioxidant and anti-virulence roles of atractylodin in attenuating Listeria monocytogenes infection.
Annexin A2 regulates Mycoplasma bovis adhesion and invasion to embryo bovine lung cells affecting molecular expression essential to inflammatory response.
Cannabidiol prevents methamphetamine-induced neurotoxicity by modulating dopamine receptor D1-mediated calcium-dependent phosphorylation of methyl-CpG-binding protein 2.
Calycosin attenuates renal ischemia/reperfusion injury by suppressing NF-κB mediated inflammation via PPARγ/EGR1 pathway.
Coxsackievirus B3 infection induces glycolysis to facilitate viral replication.
Enterovirus A71 utilizes host cell lipid β-oxidation to promote its replication.
Creatinine accelerates APAP-induced liver damage by increasing oxidative stress through ROS/JNK signaling pathway.
Vaccarin alleviates endothelial inflammatory injury in diabetes by mediating miR-570-3p/HDAC1 pathway.
SMO mutation predicts the effect of immune checkpoint inhibitor: From NSCLC to multiple cancers.
Chrysophanol-8-O-glucoside protects mice against acute liver injury by inhibiting autophagy in hepatic stellate cells and inflammatory response in liver-resident macrophages.
Therapeutic effects and mechanisms of N-(9,10-anthraquinone-2-ylcarbonyl) xanthine oxidase inhibitors on hyperuricemia.
Network pharmacology and experimental analysis to reveal the mechanism of Dan-Shen-Yin against endothelial to mesenchymal transition in atherosclerosis.
(±)-5-bromo-2-(5-fluoro-1-hydroxyamyl) Benzoate Protects Against Oxidative Stress Injury in PC12 Cells Exposed to H(2)O(2) Through Activation of Nrf2 Pathway.
Mycoplasma bovis inhibits autophagy in bovine mammary epithelial cells via a PTEN/PI3K-Akt-mTOR-dependent pathway.
Identification of the effect and mechanism of Yiyi Fuzi Baijiang powder against colorectal cancer using network pharmacology and experimental validation.
PM2.5 Synergizes With Pseudomonas aeruginosa to Suppress Alveolar Macrophage Function in Mice Through the mTOR Pathway.
Transcriptomic Analysis of Dysregulated Genes of the nDNA-mtDNA Axis in a Mouse Model of Dilated Cardiomyopathy.
Allyl methyl trisulfide protected against LPS-induced acute lung injury in mice via inhibition of the NF-κB and MAPK pathways.
Role of complement C1q/C3-CR3 signaling in brain injury after experimental intracerebral hemorrhage and the effect of minocycline treatment.
Reduced Immunity Regulator MAVS Contributes to Non-Hypertrophic Cardiac Dysfunction by Disturbing Energy Metabolism and Mitochondrial Homeostasis.
Yi-Shen-Hua-Shi Granule Alleviates Adriamycin-Induced Glomerular Fibrosis by Suppressing the BMP2/Smad Signaling Pathway.
ATP-citrate lyase inhibitor improves ectopic lipid accumulation in the kidney in a db/db mouse model.
Berberrubine, a Main Metabolite of Berberine, Alleviates Non-Alcoholic Fatty Liver Disease via Modulating Glucose and Lipid Metabolism and Restoring Gut Microbiota.
Cisplatin-Induced Anorexia and Pica Behavior in Rats Enhanced by Chronic Stress Pretreatment.
Curcumol Suppresses CCF-Mediated Hepatocyte Senescence Through Blocking LC3B-Lamin B1 Interaction in Alcoholic Fatty Liver Disease.
Empagliflozin Attenuates Obesity-Related Kidney Dysfunction and NLRP3 Inflammasome Activity Through the HO-1-Adiponectin Axis.
Total extract of Abelmoschus manihot L. alleviates uric acid-induced renal tubular epithelial injury via inhibition of caspase-8/caspase-3/NLRP3/GSDME signaling.
Furfural Produces Dose-Dependent Attenuating Effects on Ethanol-Induced Toxicity in the Liver.
Ninjinyoeito improves social behavior disorder in neuropeptide Y deficient zebrafish.
A Mechanistic Exploratory Study on the Therapeutic Efficacy of Astragaloside IV Against Diabetic Retinopathy Revealed by Network Pharmacology.
Csf2ra deletion attenuates acute lung injuries induced by intratracheal inoculation of aerosolized ricin in mice.
USP7 Promotes deubiquitination and stabilization of MyD88 to enhance immune responses.
Transcriptomics and Network Pharmacology Reveal the Protective Effect of Chaiqin Chengqi Decoction on Obesity-Related Alcohol-Induced Acute Pancreatitis via Oxidative Stress and PI3K/Akt Signaling Pathway.
Astragalus-Scorpion Drug Pair Inhibits the Development of Prostate Cancer by Regulating GDPD4-2/PI3K/AKT/mTOR Pathway and Autophagy.
Natural Compound Library Screening Identifies Oroxin A for the Treatment of Myocardial Ischemia/Reperfusion Injury.
EGFR Activation Impairs Antiviral Activity of Interferon Signaling in Brain Microvascular Endothelial Cells During Japanese Encephalitis Virus Infection.
A ROCK1 Inhibitior Fasudil Alleviates Cardiomyocyte Apoptosis in Diabetic Cardiomyopathy by Inhibiting Mitochondrial Fission in a Type 2 Diabetes Mouse Model.
Oridonin Delays Aging Through the AKT Signaling Pathway.
TIPE2 May Target the Nrf2/HO-1 Pathway to Inhibit M1 Macrophage-Related Neutrophilic Inflammation in Asthma.
Engineered Exosomes-Mediated Transfer of hsa-miR-320a Overcomes Chemoresistance in Cervical Cancer Cells via Targeting MCL1.
Pan-Cancer Analysis of the Immunological Role of PDIA5: A Potential Target for Immunotherapy.
Host MKRN1-Mediated Mycobacterial PPE Protein Ubiquitination Suppresses Innate Immune Response.
Hepatotoxicity of the Major Anthraquinones Derived From Polygoni Multiflori Radix Based on Bile Acid Homeostasis.
Clinical significance of SPOCK2 expression signature for high-grade serous ovarian cancer patients.
Baohuoside I Inhibits Osteoclastogenesis and Protects Against Ovariectomy-Induced Bone Loss.
Ginsenoside Rb1 Ameliorated Bavachin-Induced Renal Fibrosis via Suppressing Bip/eIF2α/CHOP Signaling-Mediated EMT.
Effects of Pereskia aculeate Miller Petroleum Ether Extract on Complete Freund's Adjuvant-Induced Rheumatoid Arthritis in Rats and its Potential Molecular Mechanisms.
Knockdown of NRSF Alleviates Ischemic Brain Injury and Microvasculature Defects in Diabetic MCAO Mice.
Vitamin D3 Suppresses Human Cytomegalovirus-Induced Vascular Endothelial Apoptosis via Rectification of Paradoxical m6A Modification of Mitochondrial Calcium Uniporter mRNA, Which Is Regulated by METTL3 and YTHDF3.
Single Cell Dissection of Epithelial-Immune Cellular Interplay in Acute Kidney Injury Microenvironment.
AQP2 Promotes Astrocyte Activation by Modulating the TLR4/NFκB-p65 Pathway Following Intracerebral Hemorrhage.
The Construction and Immunogenicity Analyses of Recombinant Pseudorabies Virus With NADC30-Like Porcine Reproductive and Respiratory Syndrome Virus-Like Particles Co-expression.
Saikosaponin D Inhibited IL-1β Induced ATDC 5 Chondrocytes Apoptosis In Vitro and Delayed Articular Cartilage Degeneration in OA Model Mice In Vivo.
Network Pharmacology-Based Strategy to Identify the Pharmacological Mechanisms of Pulsatilla Decoction against Crohn's Disease.
Dan-Shen-Yin Granules Prevent Hypoxia-Induced Pulmonary Hypertension via STAT3/HIF-1α/VEGF and FAK/AKT Signaling Pathways.
Exogenous Linoleic Acid Intervention Alters Hepatic Glucose Metabolism in an Avian Embryo Model.
Polysaccharides From the Aerial Parts of Tetrastigma Hemsleyanum Diels et Gilg Induce Bidirectional Immunity and Ameliorate LPS-Induced Acute Respiratory Distress Syndrome in Mice.
Effect of Xiongmatang Extract on Behavioral and TRPV1-CGRP/CGRP-R Pathway in Rats With Migraine.
Dihydromyricetin Alleviates Pulmonary Fibrosis by Regulating Abnormal Fibroblasts Through the STAT3/p-STAT3/GLUT1 Signaling Pathway.
Antigen Presentation Machinery Signature-Derived CALR Mediates Migration, Polarization of Macrophages in Glioma and Predicts Immunotherapy Response.
Lactobacillus plantarum RS-09 Induces M1-Type Macrophage Immunity Against Salmonella Typhimurium Challenge via the TLR2/NF-κB Signalling Pathway.
Asiatic Acid Attenuates Osteoporotic Bone Loss in Ovariectomized Mice Through Inhibiting NF-kappaB/MAPK/ Protein Kinase B Signaling Pathway.
ALG-bFGF Hydrogel Inhibiting Autophagy Contributes to Protection of Blood-Spinal Cord Barrier Integrity via PI3K/Akt/FOXO1/KLF4 Pathway After SCI.
Trilobatin, a Natural Food Additive, Exerts Anti-Type 2 Diabetes Effect Mediated by Nrf2/ARE and IRS-1/GLUT2 Signaling Pathways.
Recovery Infectious Enterovirus 71 by Bac-to-Bac Expression System in vitro and in vivo.
An RRx-001 Analogue With Potent Anti-NLRP3 Inflammasome Activity but Without High-Energy Nitro Functional Groups.
Cold Exposure Induces Intestinal Barrier Damage and Endoplasmic Reticulum Stress in the Colon via the SIRT1/Nrf2 Signaling Pathway.
Characterization of a Novel Monoclonal Antibody for Serine-129 Phosphorylated α-Synuclein: A Potential Application for Clinical and Basic Research.
Gut microbiota-mediated metabolic restructuring aggravates emotional deficits after anesthesia/surgery in rats with preoperative stress.
Propofol Augments Paclitaxel-Induced Cervical Cancer Cell Ferroptosis In Vitro.
Metabolomics Analysis of the Prefrontal Cortex in a Rat Chronic Unpredictable Mild Stress Model of Depression.
OPN5 Regulating Mechanism of Follicle Development Through the TSH-DIO2/DIO3 Pathway in Mountain Ducks Under Different Photoperiods.
The Role of RNA-Binding Protein HuR in Lung Cancer by RNA Sequencing Analysis.
Salidroside Ameliorates Depression by Suppressing NLRP3-Mediated Pyroptosis via P2X7/NF-κB/NLRP3 Signaling Pathway.
Uncovering the Pharmacological Mechanisms of Gexia-Zhuyu Formula (GXZY) in Treating Liver Cirrhosis by an Integrative Pharmacology Strategy.
RNA 2'-O-Methyltransferase Fibrillarin Facilitates Virus Entry Into Macrophages Through Inhibiting Type I Interferon Response.
Molecular Mechanisms Underlying the Inhibition of Proliferation and Differentiation by Florfenicol in P19 Stem Cells: Transcriptome Analysis.
Cinnamaldehyde Suppressed EGF-Induced EMT Process and Inhibits Ovarian Cancer Progression Through PI3K/AKT Pathway.
The Antitumor Effect and Mechanism of Total Flavonoids From Coreopsis Tinctoria Nutt (Snow Chrysanthemum) on Lung Cancer Using Network Pharmacology and Molecular Docking.
Inflammatory-Dependent Bidirectional Effect of Bile Acids on NLRP3 Inflammasome and Its Role in Ameliorating CPT-11-Induced Colitis.
Astragalus propinquus schischkin and Salvia miltiorrhiza bunge promote angiogenesis to treat myocardial ischemia via Ang-1/Tie-2/FAK pathway.
Deleterious variants in TAF7L cause human oligoasthenoteratozoospermia and its impairing histone to protamine exchange inducing reduced in vitro fertilization.
Wogonin increases gemcitabine sensitivity in pancreatic cancer by inhibiting Akt pathway.
Neuregulin-1β increases glucose uptake and promotes GLUT4 translocation in palmitate-treated C2C12 myotubes by activating PI3K/AKT signaling pathway.
Calycosin induces autophagy and apoptosis via Sestrin2/AMPK/mTOR in human papillary thyroid cancer cells.
Integrated network pharmacology and serum metabolomics approach deciphers the anti-colon cancer mechanisms of Huangqi Guizhi Wuwu Decoction.
Sleeve gastrectomy improves lipid dysmetabolism by downregulating the USP20-HSPA2 axis in diet-induced obese mice.
Pathophysiological conditions induced by SARS-CoV-2 infection reduce ACE2 expression in the lung.
Protein-protein interactions between RUNX3 and ZEB1 in chronic lung injury induced by methamphetamine abuse.
Enterovirus 71 non-structural protein 3A hijacks vacuolar protein sorting 25 to boost exosome biogenesis to facilitate viral replication.
Forsythiaside B ameliorates coagulopathies in a rat model of sepsis through inhibition of the formation of PAD4-dependent neutrophil extracellular traps.
Improvement of gut-vascular barrier by terlipressin reduces bacterial translocation and remote organ injuries in gut-derived sepsis.
Sleeve gastrectomy attenuated diabetes-related cognitive decline in diabetic rats.
Exploitation of tumor antigens and construction of immune subtype classifier for mRNA vaccine development in bladder cancer.
Clinical identification of expressed proteins in adrenal medullary hyperplasia detected with hypertension.
Dual immunological and proliferative regulation of immune checkpoint FGL1 in lung adenocarcinoma: The pivotal role of the YY1-FGL1-MYH9 axis.
X-box binding protein 1: A new metabolic mediator and drug target of metformin?
Sunitinib induced hepatotoxicity in L02 cells via ROS-MAPKs signaling pathway.
COA3 overexpression promotes non-small cell lung cancer metastasis by reprogramming glucose metabolism.
M2 microglia-derived extracellular vesicles promote white matter repair and functional recovery via miR-23a-5p after cerebral ischemia in mice.
miR-1297 inhibits osteosarcoma cell proliferation and growth by targeting CCND2.
Hepatic RACK1 deficiency protects against fulminant hepatitis through myeloid-derived suppressor cells.
Exosome-mediated delivery of RBP-J decoy oligodeoxynucleotides ameliorates hepatic fibrosis in mice.
Mitochondrial STAT3 exacerbates LPS-induced sepsis by driving CPT1a-mediated fatty acid oxidation.
Methionine deprivation inhibits glioma growth through downregulation of CTSL.
Integrative proteomics and m6A microarray analyses of the signatures induced by METTL3 reveals prognostically significant in gastric cancer by affecting cellular metabolism.
Identification of pyroptosis-related lncRNA signature and AC005253.1 as a pyroptosis-related oncogene in prostate cancer.
FTO promotes liver inflammation by suppressing m6A mRNA methylation of IL-17RA.
Construction and validation of a prognostic model with RNA binding protein-related mRNAs for the HBV-related hepatocellular carcinoma patients.
Effects of glycolysis and polyamine predation on intestinal epithelial barrier in colorectal cancer.
Pan-cancer analysis reveals DDX21 as a potential biomarker for the prognosis of multiple tumor types.
Silenced LINC01134 Enhances Oxaliplatin Sensitivity by Facilitating Ferroptosis Through GPX4 in Hepatocarcinoma.
CAPRIN2 upregulation by LINC00941 promotes nasopharyngeal carcinoma ferroptosis resistance and metastatic colonization through HMGCR.
Loss of exosomal micro-RNA-200b-3p from hypoxia cancer-associated fibroblasts reduces sensitivity to 5-flourouracil in colorectal cancer through targeting high-mobility group box 3.
ESR1 Regulates the Obesity- and Metabolism-Differential Gene MMAA to Inhibit the Occurrence and Development of Hepatocellular Carcinoma.
High-Metastatic Melanoma Cells Promote the Metastatic Capability of Low-Metastatic Melanoma Cells via Exosomal Transfer of miR-411-5p.
ITGB5 promotes innate radiation resistance in pancreatic adenocarcinoma by promoting DNA damage repair and the MEK/ERK signaling pathway.
TFAP2C-Mediated lncRNA PCAT1 Inhibits Ferroptosis in Docetaxel-Resistant Prostate Cancer Through c-Myc/miR-25-3p/SLC7A11 Signaling.
Mitochondrion-Localized SND1 Promotes Mitophagy and Liver Cancer Progression Through PGAM5.
Up-Regulation of TRIM32 Associated With the Poor Prognosis of Acute Myeloid Leukemia by Integrated Bioinformatics Analysis With External Validation.
FGF19 Is Coamplified With CCND1 to Promote Proliferation in Lung Squamous Cell Carcinoma and Their Combined Inhibition Shows Improved Efficacy.
Knockdown of hnRNPA1 Promotes NSCLC Metastasis and EMT by Regulating Alternative Splicing of LAS1L exon 9.
Olaparib Induces RPL5/RPL11-Dependent p53 Activation via Nucleolar Stress.
Inhibition of NEK7 Suppressed Hepatocellular Carcinoma Progression by Mediating Cancer Cell Pyroptosis.
Thymidine Kinase 1 Drives Skin Cutaneous Melanoma Malignant Progression and Metabolic Reprogramming.
Syntenin Regulated by miR-216b Promotes Cancer Progression in Pancreatic Cancer.
Overexpression of CDCA8 Predicts Poor Prognosis and Promotes Tumor Cell Growth in Prostate Cancer.
Transient Receptor Potential Cation Channel Subfamily V Member 1 Expression Promotes Chemoresistance in Non-Small-Cell Lung Cancer.
Anti-Tumor Role of CAMK2B in Remodeling the Stromal Microenvironment and Inhibiting Proliferation in Papillary Renal Cell Carcinoma.
Dual-fluorescent reporter for live-cell imaging of the ER during DENV infection.
Inhibition of RNF182 mediated by Bap promotes non-small cell lung cancer progression.
Polysaccharides from Vaccaria segetalis seeds reduce urinary tract infections by inhibiting the adhesion and invasion abilities of uropathogenic Escherichia coli.
Retrospective analysis of the efficacy of adjuvant cytokine-induced killer cell immunotherapy combined with chemotherapy in colorectal cancer patients after surgery.
CAV1 alleviated CaOx stones formation via suppressing autophagy-dependent ferroptosis.
Involvement of PI3K/Akt signaling pathway in promoting osteogenesis on titanium implant surfaces modified with novel non-thermal atmospheric plasma.
Adhesive, injectable, and ROS-responsive hybrid polyvinyl alcohol (PVA) hydrogel co-delivers metformin and fibroblast growth factor 21 (FGF21) for enhanced diabetic wound repair.
Expression profiles of exosomal tRNA-derived fragments and their biological functions in lipomas.
Manganese-Based Prussian Blue Nanocatalysts Suppress Non-Small Cell Lung Cancer Growth and Metastasis via Photothermal and Chemodynamic Therapy.
Extracellular vimentin is expressed at the rear of activated macrophage-like cells: Potential role in enhancement of migration and phagocytosis.
The Apoptotic Resistance of BRCA1-Deficient Ovarian Cancer Cells is Mediated by cAMP.
The Maternal Microbiome Programs the m(6)A Epitranscriptome of the Mouse Fetal Brain and Intestine.
Umbilical Cord Mesenchymal Stem Cells Ameliorate Kidney Injury in MRL/Ipr Mice Through the TGF-β1 Pathway.
Reciprocal Regulation of Mitofusin 2-Mediated Mitophagy and Mitochondrial Fusion by Different PINK1 Phosphorylation Events.
AZD5153, a Bivalent BRD4 Inhibitor, Suppresses Hepatocarcinogenesis by Altering BRD4 Chromosomal Landscape and Modulating the Transcriptome of HCC Cells.
miR-381-3p Cooperated With Hes1 to Regulate the Proliferation and Differentiation of Retinal Progenitor Cells.
Elucidating the Potential Mechanisms Underlying Distraction Spinal Cord Injury-Associated Neuroinflammation and Apoptosis.
Adenosine Kinase Inhibition Prevents Severe Acute Pancreatitis via Suppressing Inflammation and Acinar Cell Necroptosis.
Inhibition of the NLRP3 Inflammasome Activation by Manoalide Ameliorates Experimental Autoimmune Encephalomyelitis Pathogenesis.
PLK1 Mitigates Intervertebral Disc Degeneration by Delaying Senescence of Nucleus Pulposus Cells.
Quercetin Administration Following Hypoxia-Induced Neonatal Brain Damage Attenuates Later-Life Seizure Susceptibility and Anxiety-Related Behavior: Modulating Inflammatory Response.
Platelet-rich plasma attenuates the severity of joint capsule fibrosis following post-traumatic joint contracture in rats.
Construction and osteogenic effects of 3D-printed porous titanium alloy loaded with VEGF/BMP-2 shell-core microspheres in a sustained-release system.
BCAT1 promotes lung adenocarcinoma progression through enhanced mitochondrial function and NF-κB pathway activation.
The E3 Ligase TRIM4 Facilitates SET Ubiquitin-Mediated Degradation to Enhance ER-α Action in Breast Cancer.
Icariside II suppresses the tumorigenesis and development of ovarian cancer by regulating miR-144-3p/IGF2R axis.
Quercetin ameliorates salivary gland apoptosis and inflammation in primary Sjögren's syndrome through regulation of the leptin/OB-R signaling.
Carotenoid transporter CD36 expression depends on hypoxia-inducible factor-1α in mouse soleus muscles.
HSPA5 repressed ferroptosis to promote colorectal cancer development by maintaining GPX4 stability.
Insulin Deficiency Increases Sirt2 Level in Streptozotocin-Treated Alzheimer's Disease-Like Mouse Model: Increased Sirt2 Induces Tau Phosphorylation Through ERK Activation.
Nav1.8 in keratinocytes contributes to ROS-mediated inflammation in inflammatory skin diseases.
A possible mechanism to the antidepressant-like effects of 20 (S)-protopanaxadiol based on its target protein 14-3-3 ζ.
KRAS-G12D mutation drives immune suppression and the primary resistance of anti-PD-1/PD-L1 immunotherapy in non-small cell lung cancer.
Serum-derived exosomes from SD rats induce inflammation in macrophages through the mTOR pathway.
FumDSB can alleviate the inflammatory response induced by fumonisin B(1) in growing pigs.
Exosomal miR-7002-5p derived from highglucose-induced macrophages suppresses autophagy in tubular epithelial cells by targeting Atg9b.
Androgen receptor splicing variant 7 (ARv7) promotes DNA damage response in prostate cancer cells.
Trehalose improves palmitic acid-induced apoptosis of osteoblasts by regulating SIRT3-medicated autophagy via the AMPK/mTOR/ULK1 pathway.
A novel role of TCAIM: suppressing renal carcinoma growth and enhancing its sensitivity to sunitinib.
Rare variants in GABRG2 associated with sleep-related hypermotor epilepsy.
Identification of ferroptosis-related genes for the prediction of prognosis and chemotherapy benefit of gastric cancer.
Epigallocatechin-3-gallate attenuates myocardial fibrosis in diabetic rats by activating autophagy.
Integrated analysis of ALK higher expression in human cancer and downregulation in LUAD using RNA molecular scissors.
Salvianolic Acid B Alleviates Myocardial Ischemia Injury by Suppressing NLRP3 Inflammasome Activation via SIRT1-AMPK-PGC-1α Signaling Pathway.
Inhibition of 8-oxoguanine DNA glycosylase (OGG1) expression suppresses polycystic ovarian syndrome via the NF-κB signaling pathway.
DI-3-n-butylphthalide mitigates stress-induced cognitive deficits in mice through inhibition of NLRP3-Mediated neuroinflammation.
High-circulating gut microbiota-dependent metabolite trimethylamine N-oxide is associated with poor prognosis in pulmonary arterial hypertension.
Protective effects of fraxin on cerebral ischemia-reperfusion injury by mediating neuroinflammation and oxidative stress through PPAR-γ/NF-κB pathway.
Transcranial focused ultrasound stimulation reduces vasogenic edema after middle cerebral artery occlusion in mice.
Urolithin A alleviates blood-brain barrier disruption and attenuates neuronal apoptosis following traumatic brain injury in mice.
Phospho-proteomics reveals that RSK signaling is required for proliferation of natural killer cells stimulated with IL-2 or IL-15.
Effect of flavonoids from Rhizoma Drynariae on osteoporosis rats and osteocytes.
Compromised glycolysis contributes to foot process fusion of podocytes in diabetic kidney disease: Role of ornithine catabolism.
NF-κB-coupled IL17 mediates inflammatory signaling and intestinal inflammation in Artemia sinica.
LncRNA DACH1 protects against pulmonary fibrosis by binding to SRSF1 to suppress CTNNB1 accumulation.
The ubiquitin-26S proteasome system and autophagy relay proteome homeostasis regulation during silique development.
7-O-(2- (Propylamino)-2-oxoethyl) hesperetin attenuates inflammation and protects against alcoholic liver injury by NLRP12.
Hirudin alleviates acute ischemic stroke by inhibiting NLRP3 inflammasome-mediated neuroinflammation: In vivo and in vitro approaches.
High expression of PTGES3 is an independent predictive poor prognostic biomarker and correlates with immune infiltrates in lung adenocarcinoma.
Neobavaisoflavone inhibits allergic inflammatory responses by suppressing mast cell activation.
Luteolin ameliorates hypoxia-induced pulmonary hypertension via regulating HIF-2α-Arg-NO axis and PI3K-AKT-eNOS-NO signaling pathway.
Iristectorigenin A exerts novel protective properties against airway inflammation and mucus hypersecretion in OVA-induced asthmatic mice: Iristectorigenin A ameliorates asthma phenotype.
Serum exosomal coronin 1A and dynamin 2 as neural tube defect biomarkers.
Biomimetic cytomembrane-coated ZIF-8-loaded DMDD nanoparticle and sonodynamic co-therapy for cancer.
Growth advantage of corrected hepatocytes in a juvenile model of methylmalonic acidemia following liver directed adeno-associated viral mediated nuclease-free genome editing.
Achyranthoside D (AD) improve intervertebral disc degeneration through affect the autophagy and the activation of PI3K/Akt/mTOR pathway.
Topoisomerase IIA in adult NSCs regulates SVZ neurogenesis by transcriptional activation of Usp37.
Integrative network analysis of circular RNAs reveals regulatory mechanisms for hepatic specification of human iPSC-derived endoderm.
Identification of a small-molecule RPL11 mimetic that inhibits tumor growth by targeting MDM2-p53 pathway.
Acid ceramidase targeting pyruvate kinase affected trypsinogen activation in acute pancreatitis.
The histone modification reader ZCWPW1 promotes double-strand break repair by regulating cross-talk of histone modifications and chromatin accessibility at meiotic hotspots.
TRIM46 aggravated high glucose-induced hyper permeability and inflammatory response in human retinal capillary endothelial cells by promoting IκBα ubiquitination.
Membrane-associated RING-CH protein (MARCH8) is a novel glycolysis repressor targeted by miR-32 in colorectal cancer.
The MBNL1/circNTRK2/PAX5 pathway regulates aerobic glycolysis in glioblastoma cells by encoding a novel protein NTRK2-243aa.
CLDN4 promotes growth of acute myeloid leukemia cells via regulating AKT and ERK1/2 signaling.
FOXD1 facilitates pancreatic cancer cell proliferation, invasion, and metastasis by regulating GLUT1-mediated aerobic glycolysis.
Inhibition of Mcl-1 Synergistically Enhances the Antileukemic Activity of Gilteritinib and MRX-2843 in Preclinical Models of FLT3-Mutated Acute Myeloid Leukemia.
SPLUNC1 regulates LPS-induced progression of nasopharyngeal carcinoma and proliferation of myeloid-derived suppressor cells.
Exosomal miR-22-3p from Mesenchymal Stem Cells Inhibits the Epithelial-Mesenchymal Transition (EMT) of Melanoma Cells by Regulating LGALS1.
Effects of growth hormone/estrogen/androgen on COVID-19-type proinflammatory responses in normal human lung epithelial BEAS-2B cells.
Grass Carp Prx 3 Elevates Host Antioxidant Activity and Induces Autophagy to Inhibit Grass Carp Reovirus (GCRV) Replication.
Rabphilin 3A binds the N-peptide of SNAP-25 to promote SNARE complex assembly in exocytosis.
Nonstructural Protein 1 of Variant PEDV Plays a Key Role in Escaping Replication Restriction by Complement C3.
Single cell analysis of PANoptosome cell death complexes through an expansion microscopy method.
Post-Injury Buprenorphine Administration Is Associated with Long-Term Region-Specific Glial Alterations in Rats.
Impad1 and Syt11 work in an epistatic pathway that regulates EMT-mediated vesicular trafficking to drive lung cancer invasion and metastasis.
Inhibiting ALK-TOPK signaling pathway promotes cell apoptosis of ALK-positive NSCLC.
Differential requirements for mitochondrial electron transport chain components in the adult murine liver.
PIKE-A Modulates Mitochondrial Metabolism through Increasing SDHA Expression Mediated by STAT3/FTO Axis.
Exploring Active Ingredients, Beneficial Effects, and Potential Mechanism of Allium tenuissimum L. Flower for Treating T2DM Mice Based on Network Pharmacology and Gut Microbiota.
7-aminocephalosporanic acid, a novel HSP90β inhibitor, attenuates HFD-induced hepatic steatosis.
Gastrodin Ameliorates Cognitive Dysfunction in Vascular Dementia Rats by Suppressing Ferroptosis via the Regulation of the Nrf2/Keap1-GPx4 Signaling Pathway.
PKM2 promotes pulmonary fibrosis by stabilizing TGF-β1 receptor I and enhancing TGF-β1 signaling.
Design, Synthesis, and Biological Evaluation of Androgen Receptor Degrading and Antagonizing Bifunctional Steroidal Analogs for the Treatment of Advanced Prostate Cancer.
Akebia Saponin D Inhibits the Inflammatory Reaction by Inhibiting the IL-6-STAT3-DNMT3b Axis and Activating the Nrf2 Pathway.
TOP2A deficit-induced abnormal decidualization leads to recurrent implantation failure via the NF-κB signaling pathway.
SHP-1/STAT3-Signaling-Axis-Regulated Coupling between BECN1 and SLC7A11 Contributes to Sorafenib-Induced Ferroptosis in Hepatocellular Carcinoma.
Correlation of the prognostic value of FNDC4 in glioblastoma with macrophage polarization.
A causal variant rs3769823 in 2q33.1 involved in apoptosis pathway leading to a decreased risk of non-small cell lung cancer.
KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer.
Asiatic Acid Attenuates Inflammation Induced by Salmonella via Upregulating LncRNA TVX1 in Microglia.
TWIST1 induces proteasomal degradation of β-catenin during the differentiation of ovarian cancer stem-like cells.
Isoalantolactone (IAL) Regulates Neuro-Inflammation and Neuronal Apoptosis to Curb Pathology of Parkinson's Disease.
PD-1 Alleviates Cisplatin-Induced Muscle Atrophy by Regulating Inflammation and Oxidative Stress.
CTCF DNA-binding domain undergoes dynamic and selective protein-protein interactions.
Pericyte mediates the infiltration, migration, and polarization of macrophages by CD163/MCAM axis in glioblastoma.
Kaempferol impairs aerobic glycolysis against melanoma metastasis via inhibiting the mitochondrial binding of HK2 and VDAC1.
Alpha1B-adreneroceptor is involved in norepinephrine-induced pulmonary artery smooth muscle cell proliferation via p38 signaling.
Aberrant human ClpP activation disturbs mitochondrial proteome homeostasis to suppress pancreatic ductal adenocarcinoma.
Purple sweet potato delphinidin-3-rutin represses glioma proliferation by inducing miR-20b-5p/Atg7-dependent cytostatic autophagy.
African Swine Fever Virus pI215L Inhibits Type I Interferon Signaling by Targeting Interferon Regulatory Factor 9 for Autophagic Degradation.
CIDEA Regulates De Novo Fatty Acid Synthesis in Bovine Mammary Epithelial Cells by Targeting the AMPK/PPARγ Axis and Regulating SREBP1.
Chemically modified in-vitro-transcribed mRNA encoding thrombopoietin stimulates thrombopoiesis in mice.
Deubiquitination of BES1 by UBP12/UBP13 promotes brassinosteroid signaling and plant growth.
Direct conversion of human umbilical cord mesenchymal stem cells into retinal pigment epithelial cells for treatment of retinal degeneration.
GCAF(TMEM251) regulates lysosome biogenesis by activating the mannose-6-phosphate pathway.
COPS5 Conferred the Platinum Resistance in Epithelial Ovarian Cancer.
MCPIP1 promotes cell proliferation, migration and angiogenesis of glioma via VEGFA-mediated ERK pathway.
Flufenamic acid improves survival and neurologic outcome after successful cardiopulmonary resuscitation in mice.
Tumor-intrinsic PRC2 inactivation drives a context-dependent immune-desert microenvironment and is sensitized by immunogenic viruses.
Metabolism-Based Molecular Subtyping Endows Effective Ketogenic Therapy in p53-Mutant Colon Cancer.
TCQA, A Natural Caffeoylquinic Acid Derivative Attenuates H2O2-Induced Neuronal Apoptosis by Suppressing Phosphorylation of MAPKs Signaling Pathway.
Identification of active natural products that induce lysosomal biogenesis by lysosome-based screening and biological evaluation.
Oleuropein ameliorated lung ischemia-reperfusion injury by inhibiting TLR4 signaling cascade in alveolar macrophages.
EphA4 regulates white matter remyelination after ischemic stroke through Ephexin-1/RhoA/ROCK signaling pathway.
TCF3 protein was highly expressed in pediatric Burkitt lymphoma and predicts poor prognosis: a single-center study.
A Dual-Action Molecule Suppresses S. aureus Infection as an Inhibitor Targeting Hla Pore Formation and TLR2 Signaling.
GDNF Promotes Astrocyte Abnormal Proliferation and Migration Through the GFRα1/RET/MAPK/pCREB/LOXL2 Signaling Axis.
Impact of Resolvin D1 on the inflammatory phenotype of periodontal ligament cell response to hypoxia.
PGC-1α attenuates TNF-α-induced inflammatory responses in OCCM-30 cells.
Quercetin in Tonglong Qibi decoction ameliorates testosterone-induced benign prostatic hyperplasia in rats by regulating Nrf2 signalling pathways and oxidative stress.
The c.612A>G mutation of MC4R affects constitutive activity and signaling in domestic goats.
Catalpol Exerts Antidepressant-Like Effects by Enhancing Anti-oxidation and Neurotrophy and Inhibiting Neuroinflammation via Activation of HO-1.
Proteasomal deubiquitylase activity enhances cell surface recycling of the epidermal growth factor receptor in non-small cell lung cancer.
Effect of the Pulsed Electromagnetic Field Treatment in a Rat Model of Senile Osteoporosis In Vivo.
Inducement of ER Stress by PAD Inhibitor BB-Cl-Amidine to Effectively Kill AML Cells.
Network pharmacology and molecular docking study on the effect of Kaempferol in treatment of metabolic associated fatty liver disease.
Ultrasound-based radiomics for the evaluation of fetal rat lung maturity: A noninvasive assessment method (Ultrasound-based radiomics in fetal rat lung).
Sestrin2 attenuates renal damage by regulating Hippo pathway in diabetic nephropathy.
Hepatic cytokine-inducible SH2-containing protein (CISH) regulates gluconeogenesis via cAMP-responsive element binding protein (CREB).
Bryodulcosigenin attenuates bleomycin-induced pulmonary fibrosis via inhibiting AMPK-mediated mesenchymal epithelial transition and oxidative stress.
MicroRNA-124 attenuates PTSD-like behaviors and reduces the level of inflammatory cytokines by downregulating the expression of TRAF6 in the hippocampus of rats following single-prolonged stress.
Depression compromises antiviral innate immunity via the AVP-AHI1-Tyk2 axis.
Proteasomal degradation of WT proinsulin in pancreatic beta cells.
Proto-oncogene FAM83A contributes to casein kinase 1-mediated mitochondrial maintenance and white adipocyte differentiation.
ATG4B hinders porcine epidemic diarrhea virus replication through interacting with TRAF3 and activating type-I IFN signaling.
IL-1β induced by PRRSV co-infection inhibited CSFV C-strain proliferation via the TLR4/NF-κB/MAPK pathways and the NLRP3 inflammasome.
Pharmacologic inhibition of LAT1 predominantly suppresses transport of large neutral amino acids and downregulates global translation in cancer cells.
MiR-574-5p promotes cell proliferation by negatively regulating small C-terminal domain phosphatase 1 in esophageal squamous cell carcinoma.
Cold exposure-induced endoplasmic reticulum stress regulates autophagy through the SIRT2/FoxO1 signaling pathway.
Inka2, a novel Pak4 inhibitor, regulates actin dynamics in neuronal development.
Schisantherin D from Schisandra chinensis (Turcz.) Baill. exhibits anti-liver fibrosis capacity via modulating ETBR involved signaling, an in vitro and in vivo study.
Apelin-13 attenuates depressive-like behaviors induced by chronic unpredictable mild stress via activating AMPK/PGC-1α/FNDC5/BDNF pathway.
Babao Dan inhibits lymphangiogenesis of gastric cancer in vitro and in vivo via lncRNA-ANRIL/VEGF-C/VEGFR-3 signaling axis.
Fucoidan inhibits EGFR redistribution and potentiates sorafenib to overcome sorafenib-resistant hepatocellular carcinoma.
Gegen Qinlian decoction ameliorates murine colitis by inhibiting the expansion of Enterobacteriaceae through activating PPAR-γ signaling.
Identification by RNA-Seq of let-7 clusters as prenatal biomarkers for nonsyndromic cleft lip with palate.
LncRNA LINC00281/Annexin A2 Regulates Vascular Smooth Muscle Cell Phenotype Switching via the Nuclear Factor-Kappa B Signaling Pathway.
Lithocarpus polystachyus (Sweet Tea) water extract promotes human hepatocytes HL7702 proliferation through activation of HGF/AKT/ERK signaling pathway.
VCAM-1-binding peptide targeted cationic liposomes containing NLRP3 siRNA to modulate LDL transcytosis as a novel therapy for experimental atherosclerosis.
Triclocarban evoked neutrophil extracellular trap formation in common carp (Cyprinus carpio L.) by modulating SIRT3-mediated ROS crosstalk with ERK1/2/p38 signaling.
Synthesis and anti-inflammatory activity of paeonol derivatives with etherized aryl urea by regulating TLR4/MyD88 signaling pathway in RAW264.7 cell.
Hoxa9/meis1-transgenic zebrafish develops acute myeloid leukaemia-like disease with rapid onset and high penetrance.
Acadesine alleviates acute pancreatitis-related lung injury by mediating the barrier protective function of pulmonary microvascular endothelial cells.
Eupalinolide B attenuates lipopolysaccharide-induced acute lung injury through inhibition of NF-κB and MAPKs signaling by targeting TAK1 protein.
SCO-spondin-derived peptide NX210 rescues neurons from cerebral ischemia/reperfusion injury through modulating the Integrin-β1 mediated PI3K/Akt pathway.
High-throughput membrane-anchored proteome screening reveals PIEZO1 as a promising antibody-drug target for human esophageal squamous cell carcinoma.
Ginseng under forest exerts stronger anti-aging effects compared to garden ginseng probably via regulating PI3K/AKT/mTOR pathway, SIRT1/NF-κB pathway and intestinal flora.
Ban-xia-xie-xin-tang ameliorates hepatic steatosis by regulating Cidea and Cidec expression in HFD-fed mice.
Deletion of Smurf1 attenuates liver steatosis via stabilization of p53.
Structure-based discovery of Licoflavone B and Ginkgetin targeting c-Myc G-quadruplex to suppress c-Myc transcription and myeloma growth.
Downregulation of exosomal miR-7-5p promotes breast cancer migration and invasion by targeting RYK and participating in the atypical WNT signalling pathway.
CXCL12/CXCR7/β-arrestin1 biased signal promotes epithelial-to-mesenchymal transition of colorectal cancer by repressing miRNAs through YAP1 nuclear translocation.
Up-regulation of miR-133a-3p promotes ovary insulin resistance on granulosa cells of obese PCOS patients via inhibiting PI3K/AKT signaling.
Gandouling Mitigates CuSO(4)-Induced Heart Injury in Rats.
Progesterone Induces Apoptosis and Steroidogenesis in Porcine Placental Trophoblasts.
ZIP1(+) fibroblasts protect lung cancer against chemotherapy via connexin-43 mediated intercellular Zn(2+) transfer.
Protein disulfide isomerase blocks the interaction of LC3II-PHB2 and promotes mTOR signaling to regulate autophagy and radio/chemo-sensitivity.
Exploring the protective mechanisms of total tannins from Geum japonicum var. chinense F.Bolle in mice with hematopoietic dysfunction via the JAK2/STAT3/5 signaling pathway.
Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation.
CTRP1 prevents high fat diet-induced obesity and improves glucose homeostasis in obese and STZ-induced diabetic mice.
Upregulation of CRABP2 by TET1-mediated DNA hydroxymethylation attenuates mitochondrial apoptosis and promotes oxaliplatin resistance in gastric cancer.
Z. morio Hemolymph Relieves E. coli-Induced Mastitis by Inhibiting Inflammatory Response and Repairing the Blood-Milk Barrier.
Injectable and reactive oxygen species-scavenging gelatin hydrogel promotes neural repair in experimental traumatic brain injury.
Preparation of curcumin-loaded cochleates: characterisation, stability and antioxidant properties.
Lysine acetylome profiling in mouse hippocampus and its alterations upon FMRP deficiency linked to abnormal energy metabolism.
Interferon-Inducible Transmembrane Protein 3 (IFITM3) Restricts Rotavirus Infection.
VAMP4 regulates insulin levels by targeting secretory granules to lysosomes.
Down-regulation of NR2B receptors contributes to the analgesic and antianxiety effects of enriched environment mediated by endocannabinoid system in the inflammatory pain mice.
Srolo Bzhtang reduces inflammation and vascular remodeling via suppression of the MAPK/NF-κB signaling pathway in rats with pulmonary arterial hypertension.
RTCB Complex Regulates Stress-Induced tRNA Cleavage.
Auxin and abscisic acid antagonistically regulate ascorbic acid production via the SlMAPK8-SlARF4-SlMYB11 module in tomato.
Granulocytic MDSC with Deficient CCR5 Alleviates Lipogenesis and Inflammation in Nonalcoholic Fatty Liver Disease.
Neuropilin-1 Facilitates Pseudorabies Virus Replication and Viral Glycoprotein B Promotes Its Degradation in a Furin-Dependent Manner.
Circ007071 Inhibits Unsaturated Fatty Acid Synthesis by Interacting with miR-103-5p to Enhance PPARγ Expression in the Dairy Goat Mammary Gland.
Fucosylated Chondroitin Sulfate against Parkinson's Disease through Inhibiting Inflammation Induced by Gut Dysbiosis.
The oncoprotein MUC1 facilitates breast cancer progression by promoting Pink1-dependent mitophagy via ATAD3A destabilization.
METTL3 acetylation impedes cancer metastasis via fine-tuning its nuclear and cytosolic functions.
Environmentally-relevant concentrations of the antipsychotic drugs sulpiride and clozapine induce abnormal dopamine and serotonin signaling in zebrafish brain.
Docetaxel-resistant triple-negative breast cancer cell-derived exosomal lncRNA LINC00667 reduces the chemosensitivity of breast cancer cells to docetaxel via targeting miR-200b-3p/Bcl-2 axis.
SLC38A6, regulated by EP300-mediated modifications of H3K27ac, promotes cell proliferation, glutamine metabolism and mitochondrial respiration in hepatocellular carcinoma.
The necroptosis-inducing pseudokinase mixed lineage kinase domain-like regulates the adipogenic differentiation of pre-adipocytes.
Vascular restenosis reduction with platelet membrane coated nanoparticle directed M2 macrophage polarization.
Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration.
Histone methyltransferase Smyd2 drives adipogenesis via regulating STAT3 phosphorylation.
Argininosuccinate lyase drives activation of mutant TERT promoter in glioblastomas.
In Vitro and In Vivo Evaluation of Antidiabetic Properties and Mechanisms of Ficus tikoua Bur.
Proteomic analysis reveals zinc-finger CCHC-type containing protein 3 as a factor inhibiting virus infection by promoting innate signaling.
Astragalus polysaccharide alleviated the inhibition of CSFV C-strain replication caused by PRRSV via the TLRs/NF‑κB/TNF-α pathways.
SOX2 Promotes Invasion in Human Bladder Cancers through MMP2 Upregulation and FOXO1 Downregulation.
High RAS-related protein Rab-7a (RAB7A) expression is a poor prognostic factor in pancreatic adenocarcinoma.
Artemisia sphaerocephala Krasch polysaccharide promotes adipose thermogenesis and decreases obesity by shaping the gut microbiota.
PCSK9 promotes the progression and metastasis of colon cancer cells through regulation of EMT and PI3K/AKT signaling in tumor cells and phenotypic polarization of macrophages.
Inhibition of LSD1 with Bomedemstat Sensitizes Small Cell Lung Cancer to Immune Checkpoint Blockade and T-Cell Killing.
Structural analysis of the overoxidized Cu/Zn-superoxide dismutase in ROS-induced ALS filament formation.
LncGSAR Controls Ovarian Granulosa Cell Steroidogenesis via Sponging MiR-125b to Activate SCAP/SREBP Pathway.
The Effect of Circumscribed Exposure to the Pan-Aurora Kinase Inhibitor VX-680 on Proliferating Euploid Cells.
Cortisol Stimulates Local Progesterone Withdrawal Through Induction of AKR1C1 in Human Amnion Fibroblasts at Parturition.
Characterizing and Targeting Genes Regulated by Transcription Factor MYBL2 in Lung Adenocarcinoma Cells.
mTORC1 signaling pathway integrates estrogen and growth factor to coordinate vaginal epithelial cells proliferation and differentiation.
CGG repeat expansion in NOTCH2NLC causes mitochondrial dysfunction and progressive neurodegeneration in Drosophila model.
Stain-Free total-protein normalization enhances the reproducibility of Western blot data.
Siah1 promotes the proliferation of NSCLC cells through ubiquitinating and stabilizing Notch1.
Exosomal circRNA Scm-like with four malignant brain tumor domains 2 (circ-SFMBT2) enhances the docetaxel resistance of prostate cancer via the microRNA-136-5p/tribbles homolog 1 pathway.
Effect of muscone on anti-apoptotic ability of muskrat prostate primary cells.
lncRNA UCA1 induces autophagic gene expression via epigenetic regulation mediated by ATG16L1 and miR-132-3p in SH-SY5Y cells treated with retinoic acid.
β-Arrestin2-biased Drd2 agonist UNC9995 alleviates astrocyte inflammatory injury via interaction between β-arrestin2 and STAT3 in mouse model of depression.
Advanced glycation end products induce Aβ(1-42) deposition and cognitive decline through H19/miR-15b/BACE1 axis in diabetic encephalopathy.
Inactivation of fatty acid amide hydrolase protects against ischemic reperfusion injury-induced renal fibrogenesis.
Role of estrogen receptors in thyroid toxicity induced by mono (2-ethylhexyl) phthalate via endoplasmic reticulum stress: An in vitro mechanistic investigation.
SARS-CoV-2 ORF10 antagonizes STING-dependent interferon activation and autophagy.
Plasma exosomal miR-122 regulates the efficacy of metformin via AMPK in type 2 diabetes and hepatocellular carcinoma.
Carboxylesterase 2 induces mitochondrial dysfunction via disrupting lipid homeostasis in oral squamous cell carcinoma.
CCT4 knockdown enhances the sensitivity of cisplatin by inhibiting glycolysis in human esophageal squamous cell carcinomas.
Mutations in GCK May Lead to MODY2 by Reducing Glycogen Synthesis.
Ergosterol increases 7-dehydrocholesterol, a cholesterol precursor, and decreases cholesterol in human HepG2 cells.
NINJ1 triggers extravillous trophoblast cell dysfunction through blocking the STAT3 signaling pathway.
AIMP1 promotes multiple myeloma malignancy through interacting with ANP32A to mediate histone H3 acetylation.
Targeting epiregulin in the treatment-damaged tumor microenvironment restrains therapeutic resistance.
Repurposing an Antiepileptic Drug for the Treatment of Glioblastoma.
Cancer-associated fibroblast-secreted miR-421 promotes pancreatic cancer by regulating the SIRT3/H3K9Ac/HIF-1α axis.
Disturbing NLRP3 acetylation and inflammasome assembly inhibits androgen receptor-promoted inflammatory responses and prostate cancer progression.
Total flavonoids from the dried root of Tetrastigma hemsleyanum Diels et Gilg inhibit colorectal cancer growth through PI3K/AKT/mTOR signaling pathway.
Wogonoside attenuates liver fibrosis by triggering hepatic stellate cell ferroptosis through SOCS1/P53/SLC7A11 pathway.
The role of reelin in the pathological mechanism of depression from clinical to rodents.
Specific targeting of glioblastoma with an oncolytic virus expressing a cetuximab-CCL5 fusion protein via innate and adaptive immunity.
Atg6 promotes organismal health by suppression of cell stress and inflammation.
Wnt/beta-catenin signaling confers ferroptosis resistance by targeting GPX4 in gastric cancer.
PTX3 mediates the infiltration, migration, and inflammation-resolving-polarization of macrophages in glioblastoma.
KLF16 inhibits PEDV replication by activating the type I IFN signaling pathway.
LOC102553417 silencing facilitates the apoptosis of hepatic stellate cells via the miR‑30e/MTDH axis.
IL-17A promotes lung fibrosis through impairing mitochondrial homeostasis in type II alveolar epithelial cells.
High expression of HOXA4 in patients with glioma indicates unfavorable clinical outcomes.
A single N6-methyladenosine site regulates lncRNA HOTAIR function in breast cancer cells.
Intermittent fasting protects against Alzheimer's disease in mice by altering metabolism through remodeling of the gut microbiota.
Small immune effectors coordinate peptidoglycan-derived immunity to regulate intestinal bacteria in shrimp.
Si-Wu-Tang ameliorates bile duct ligation-induced liver fibrosis via modulating immune environment.
The dipeptidyl peptidase-4 inhibitor linagliptin ameliorates LPS-induced acute lung injury by maintenance of pulmonary microvascular barrier via activating the Epac1/AKT pathway.
B-cell receptor associated protein 31 deficiency decreases the expression of adhesion molecule CD11b/CD18 and PSGL-1 in neutrophils to ameliorate acute lung injury.
LncRNA TM1-3P Regulates Proliferation, Apoptosis and Inflammation of Fibroblasts in Osteoarthritis through miR-144-3p/ONECUT2 Axis.
A novel ceRNA regulatory network involving the long noncoding NEAT1, miRNA-466f-3p and its mRNA target in osteoblast autophagy and osteoporosis.
Schisandra chinensis Lignans Exert Antidepressant Effects by Promoting BV2 Microglia Polarization toward the M2 Phenotype through the Activation of the Cannabinoid Receptor Type-2-Signal Transducer and Activator of Transcription 6 Pathway.
In Vivo Visualization of RNAi Efficiency Using a Pumilio/FBF Protein-Based Reporter.
Increased joint loading induces subchondral bone loss of the temporomandibular joint via the RANTES-CCRs-Akt2 axis.
Glucosamine delays the progression of osteoporosis in senile mice by promoting osteoblast autophagy.
E3 Ubiquitin Ligase FBXO3 Drives Neuroinflammation to Aggravate Cerebral Ischemia/Reperfusion Injury.
UNC13D inhibits STING signaling by attenuating its oligomerization on the endoplasmic reticulum.
TRIM50 promotes NLRP3 inflammasome activation by directly inducing NLRP3 oligomerization.
The tyrosine phosphorylation of GRK2 is responsible for activated D(2)R-mediated insulin resistance.
Cadmium-induced apoptosis of Leydig cells is mediated by excessive mitochondrial fission and inhibition of mitophagy.
Defective Human SRP Induces Protein Quality Control and Triggers Stress Response.
Metformin alleviates HFD-induced oxidative stress in hepatocyte via activating SIRT6/PGC-1α/ENDOG signaling.
Transcriptome Analysis of Protection by Dendrobium Nobile Alkaloids (DNLA) against Chronic Alcoholic Liver Injury in Mice.
Tim-4 reprograms cholesterol metabolism to suppress antiviral innate immunity by disturbing the Insig1-SCAP interaction in macrophages.
IPO7 Promotes Odontoblastic Differentiation and Inhibits Osteoblastic Differentiation Through Regulation of RUNX2 Expression and Translocation.
De novo pyrimidine synthesis fuels glycolysis and confers chemoresistance in gastric cancer.
Pathological characterization of a novel mouse model expressing the PD-linked CHCHD2-T61I mutation.
Ciclopirox drives growth arrest and autophagic cell death through STAT3 in gastric cancer cells.
Targeting APLN/APJ restores blood-testis barrier and improves spermatogenesis in murine and human diabetic models.
Secreted EMC10 is upregulated in human obesity and its neutralizing antibody prevents diet-induced obesity in mice.
Monochromatic Light Pollution Exacerbates High-Fat Diet-Induced Adipocytic Hypertrophy in Mice.
Resident intruder paradigm-induced PMDD rat model of premenstrual irritability: behavioral phenotypes, drug intervention, and biomarkers.
The Clostridium Metabolite P-Cresol Sulfate Relieves Inflammation of Primary Biliary Cholangitis by Regulating Kupffer Cells.
USP14 regulates cell cycle progression through deubiquitinating CDK1 in breast cancer.
Exploring the Effective Components and Mechanism of Action of Japanese Ardisia in the Treatment of Autoimmune Hepatitis Based on Network Pharmacology and Experimental Verification.
Orally Administered Ginkgolide C Attenuates DSS-Induced Colitis by Maintaining Gut Barrier Integrity, Inhibiting Inflammatory Responses, and Regulating Intestinal Flora.
Branched-chain amino acid catabolism breaks glutamine addiction to sustain hepatocellular carcinoma progression.
Adenosine deaminase acting on RNA-1 is essential for early B lymphopoiesis.
Effective-component compatibility of Bufei Yishen formula III ameliorated COPD by improving airway epithelial cell senescence by promoting mitophagy via the NRF2/PINK1 pathway.
Functionally integrating nanoparticles alleviate deep vein thrombosis in pregnancy and rescue intrauterine growth restriction.
IL-37 alleviates Coxsackievirus B3-induced viral myocarditis via inhibiting NLRP3 inflammasome-mediated pyroptosis.
Dihydromyricetin Attenuates Depressive-like Behaviors in Mice by Inhibiting the AGE-RAGE Signaling Pathway.
Essential role of MESP1-RING1A complex in cardiac differentiation.
Characterization of Mitochondrial Alterations in Aicardi-Goutières Patients Mutated in RNASEH2A and RNASEH2B Genes.
Apigenin Ameliorates Hyperuricemia and Renal Injury through Regulation of Uric Acid Metabolism and JAK2/STAT3 Signaling Pathway.
BP5 alleviates endotoxemia-induced acute lung injury by activating Nrf2 via dual regulation of the Keap1-Nrf2 interaction and the Akt (Ser473)/GSK3β (Ser9)/Fyn pathway.
CRISPR-mediated MECOM depletion retards tumor growth by reducing cancer stem cell properties in lung squamous cell carcinoma.
Cyanidin Chloride Improves LPS-Induced Depression-Like Behavior in Mice by Ameliorating Hippocampal Inflammation and Excitotoxicity.
Girdin Promotes Tumorigenesis and Chemoresistance in Lung Adenocarcinoma by Interacting with PKM2.
HBO1 catalyzes lysine benzoylation in mammalian cells.
In vitro evaluation of platelet extracellular vesicles (PEVs) for corneal endothelial regeneration.
Circular RNA circPTPRF promotes the progression of GBM via sponging miR-1208 to up-regulate YY1.
Identification of purine biosynthesis as an NADH-sensing pathway to mediate energy stress.
Palmitic Acid Promotes Lung Metastasis of Melanomas via the TLR4/TRIF-Peli1-pNF-κB Pathway.
Bone marrow-targetable Green Tea Catechin-Based Micellar Nanocomplex for synergistic therapy of Acute myeloid leukemia.
LncRNA Airn alleviates diabetic cardiac fibrosis by inhibiting activation of cardiac fibroblasts via a m6A-IMP2-p53 axis.
Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR cytosolic complex.
Tea Tree Oil Mediates Antioxidant Factors Relish and Nrf2-Autophagy Axis Regulating the Lipid Metabolism of Macrobrachium rosenbergii.
Cadmium exposure induces pyroptosis in testicular tissue by increasing oxidative stress and activating the AIM2 inflammasome pathway.
Schisandra chinensis (Turcz.) Baill. Protects against DSS-induced colitis in mice: Involvement of TLR4/NF-κB/NLRP3 inflammasome pathway and gut microbiota.
Anti-infective therapy using species-specific activators of Staphylococcus aureus ClpP.
Promoting Effect of L-Fucose on the Regeneration of Intestinal Stem Cells through AHR/IL-22 Pathway of Intestinal Lamina Propria Monocytes.
Generative deep learning enables the discovery of a potent and selective RIPK1 inhibitor.
RAB27A promotes the proliferation and invasion of colorectal cancer cells.
Combination of tolvaptan and valsartan improves cardiac and renal functions in doxorubicin-induced heart failure in mice.
Dihydrotanshinone I Inhibits the Proliferation and Growth of Oxaliplatin-Resistant Human HCT116 Colorectal Cancer Cells.
DJ-1 Protein Inhibits Apoptosis in Cerebral Ischemia by Regulating the Notch1 and Nuclear Factor Erythroid2-Related Factor 2 Signaling Pathways.
Phosphoproteomics revealed cellular signals immediately responding to disruption of cancer amino acid homeostasis induced by inhibition of L-type amino acid transporter 1.
KIF17 maintains the epithelial phenotype of breast cancer cells and curbs tumour metastasis.
HA-ADT suppresses esophageal squamous cell carcinoma progression via apoptosis promotion and autophagy inhibition.
Mobilizing phospholipids on tumor plasma membrane implicates phosphatidylserine externalization blockade for cancer immunotherapy.
Effects of apolipoprotein E on regulating insulin sensitivity via regulating insulin receptor signalosome in caveolae.
SIRT4 Expression Ameliorates the Detrimental Effect of Heat Stress via AMPK/mTOR Signaling Pathway in BMECs.
Salidroside protects against osteoporosis in ovariectomized rats by inhibiting oxidative stress and promoting osteogenesis via Nrf2 activation.
Asperosaponin VI protects mice from sepsis by regulating Hippo and Rho signaling pathway.
SiNiSan alleviates liver injury by promoting hepatic stem cell differentiation via Wnt/β-catenin signaling pathway.
MiR-1298-5p level downregulation induced by Helicobacter pylori infection inhibits autophagy and promotes gastric cancer development by targeting MAP2K6.
MYPT1/PP1-Mediated EZH2 Dephosphorylation at S21 Promotes Epithelial-Mesenchymal Transition in Fibrosis through Control of Multiple Families of Genes.
Multistage targeting and dual inhibiting strategies based on bioengineered tumor matrix microenvironment-mediated protein nanocages for enhancing cancer biotherapy.
Macrophage-targeted delivery of siRNA to silence Mecp2 gene expression attenuates pulmonary fibrosis.
Intracellular hydroxyproline imprinting following resolution of bleomycin-induced pulmonary fibrosis.
LncRNA LINC00152 promotes oral squamous cell carcinoma growth via enhancing Upstream Transcription Factor 1 mediated Mitochondrial Ribosomal Protein L52 transcription.
Absence of TNF Leads to Alternative Activation in Peritoneal Macrophages in Experimental Listeria Monocytogenes Infection.
Neuregulin-1 regulates the conversion of M1/M2 microglia phenotype via ErbB4-dependent inhibition of the NF-κB pathway.
27-hydroxycholesterol linked high cholesterol diet to lung adenocarcinoma metastasis.
Non-oxidative pentose phosphate pathway controls regulatory T cell function by integrating metabolism and epigenetics.
Serpina3c deficiency induced necroptosis promotes non-alcoholic fatty liver disease through β-catenin/Foxo1/TLR4 signaling.
Leonurine inhibits the TXNIP/NLRP3 and NF-κB pathways via Nrf2 activation to alleviate carrageenan-induced pleurisy in mice.
iTRAQ-derived quantitative proteomics uncovers the neuroprotective property of bexarotene in a mice model of cerebral ischemia-reperfusion injury.
Schizosaccharomyces pombe Fzo1 is subjected to the ubiquitin-proteasome-mediated degradation during the stationary phase.
Cannabidiol inhibits methamphetamine-induced dopamine release via modulation of the DRD1-MeCP2-BDNF-TrkB signaling pathway.
Saccharides from Arctium lappa L. root reduce platelet activation and thrombus formation in a laser injury thrombosis mouse model.
2-Deoxy-D-glucose increases the sensitivity of glioblastoma cells to BCNU through the regulation of glycolysis, ROS and ERS pathways: In vitro and in vivo validation.
Urea transporter B downregulates polyamines levels in melanoma B16 cells via p53 activation.
A53T α-synuclein induces neurogenesis impairment and cognitive dysfunction in line M83 transgenic mice and reduces the proliferation of embryonic neural stem cells.
Pseudorabies virus tegument protein UL13 recruits RNF5 to inhibit STING-mediated antiviral immunity.
MEF2D-NR4A1-FAM134B2-mediated reticulophagy contributes to amino acid homeostasis.
M1-type microglia can induce astrocytes to deposit chondroitin sulfate proteoglycan after spinal cord injury.
Recombinant P40 protein of Schistosoma japonicum inhibits TREM-1 expression in RAW264.7 cells via FOXO3a.
Remote cyclic compression ameliorates myocardial infarction injury in rats via AMPK-dependent pathway.
Transformer 2 alpha homolog is a downstream gene of hypoxia-inducible factor 1 subunit alpha and is involved in the progression of pancreatic cancer.
Dihydroartemisinin alleviates steatosis and inflammation in nonalcoholic steatohepatitis by decreasing endoplasmic reticulum stress and oxidative stress.
GM1 ganglioside modifies microglial and neuroinflammatory responses to α-synuclein in the rat AAV-A53T α-synuclein model of Parkinson's disease.
Targeting DCLK1 overcomes 5-fluorouracil resistance in colorectal cancer through inhibiting CCAR1/β-catenin pathway-mediated cancer stemness.
Ckip-1 Mediates P. gingivalis-Suppressed Cementoblast Mineralization.
Identification of oleoylethanolamide as an endogenous ligand for HIF-3α.
Forkhead Box q1 promotes invasion and metastasis in colorectal cancer by activating the epidermal growth factor receptor pathway.
Mitochondrial apolipoprotein A-I binding protein alleviates atherosclerosis by regulating mitophagy and macrophage polarization.
BIN1 is a key regulator of proinflammatory and neurodegeneration-related activation in microglia.
Small Extracellular Vesicles Containing miR-34c Derived from Bone Marrow Mesenchymal Stem Cells Regulates Epithelial Sodium Channel via Targeting MARCKS.
Combination of berberine and low glucose inhibits gastric cancer through the PP2A/GSK3β/MCL-1 signaling pathway.
CCDC50 suppresses NLRP3 inflammasome activity by mediating autophagic degradation of NLRP3.
Targeted delivery of fat extract by platelet membrane-cloaked nanocarriers for the treatment of ischemic stroke.
Maternal Prenatal Inflammation Increases Brain Damage Susceptibility of Lipopolysaccharide in Adult Rat Offspring via COX-2/PGD-2/DPs Pathway Activation.
SM22α-lineage niche cells regulate intramembranous bone regeneration via PDGFRβ-triggered hydrogen sulfide production.
DNA methylation of miR-138 regulates cell proliferation and EMT in cervical cancer by targeting EZH2.
Therapeutic strategies targeting uPAR potentiate anti-PD-1 efficacy in diffuse-type gastric cancer.
Novel dual-targeting c-Myc inhibitor D347-2761 represses myeloma growth via blocking c-Myc/Max heterodimerization and disturbing its stability.
TARDBP Inhibits Porcine Epidemic Diarrhea Virus Replication through Degrading Viral Nucleocapsid Protein and Activating Type I Interferon Signaling.
Aberrant methylmalonylation underlies methylmalonic acidemia and is attenuated by an engineered sirtuin.
Role of Nrf2 Nucleus Translocation in Beauvericin-Induced Cell Damage in Rat Hepatocytes.
Melatonin Alleviates Oxidative Stress Induced by H(2)O(2) in Porcine Trophectoderm Cells.
Four AAs increase DMT1 abundance in duodenal brush-border membrane vesicles and enhance iron absorption in iron-deprived mice.
Antibiotic pretreatment attenuates liver ischemia-reperfusion injury by Farnesoid X receptor activation.
Premature translation termination mediated non-ER stress induced ATF6 activation by a ligand-dependent ribosomal frameshifting circuit.
[P4HA2 promotes occurrence and progression of liver cancer by regulating the PI3K/Akt/mTOR signaling pathway].
Overexpressed p-S6 associates with lymph node metastasis and predicts poor prognosis in non-small cell lung cancer.
Inhibition of the CDK2 and Cyclin A complex leads to autophagic degradation of CDK2 in cancer cells.
Microarray Profiling and Co-Expression Network Analysis of LncRNAs and mRNAs in Acute Respiratory Distress Syndrome Mouse Model.
Cystathionine-β-synthase (CBS)/H2S system promotes lymph node metastasis of esophageal squamous cell carcinoma (ESCC) by activating SIRT1.
Antisense oligonucleotides targeting the SMN2 promoter region enhance SMN2 expression in spinal muscular atrophy cell lines and mouse model.
Downregulation of lncRNA Miat contributes to the protective effect of electroacupuncture against myocardial fibrosis.
BMP4 Exerts Anti-Neurogenic Effect via Inducing Id3 during Aging.
TMCO1 expression promotes cell proliferation and induces epithelial-mesenchymal transformation in human gliomas.
Induction of p27 contributes to inhibitory effect of isorhapontigenin (ISO) on malignant transformation of human urothelial cells.
Induction of COX-2 by feline calicivirus via activation of the MEK1-ERK1/2 pathway, and attenuation of feline lung inflammation and injury by MEK1 inhibitor AZD6244 (selumetinib).
Infectious Bronchitis Virus Nsp14 Degrades JAK1 to Inhibit the JAK-STAT Signaling Pathway in HD11 Cells.
Hsa_circ_0000345 inhibits cell proliferation, migration and invasion of nasopharyngeal carcinoma cells via miR-513a-3p/PTEN axis.
Human epididymis protein 4 aggravates airway inflammation and remodeling in chronic obstructive pulmonary disease.
Pu-erh Tea Restored Circadian Rhythm Disruption by Regulating Tryptophan Metabolism.
Temporal Dynamics of the Ruminant Type I IFN-Induced Antiviral State against Homologous Parainfluenza Virus 3 Challenge In Vitro.
TGR5 Agonist INT-777 Alleviates Inflammatory Neurodegeneration in Parkinson's Disease Mouse Model by Modulating Mitochondrial Dynamics in Microglia.
Effect of 1-Deoxynojirimycin on insulin resistance in prediabetic mice based on next-generation sequencing and intestinal microbiota study.
P-Coumaric Acid Reverses Depression-Like Behavior and Memory Deficit Via Inhibiting AGE-RAGE-Mediated Neuroinflammation.
Hepatokine ERAP1 Disturbs Skeletal Muscle Insulin Sensitivity Via Inhibiting USP33-Mediated ADRB2 Deubiquitination.
Design, synthesis and activity study of a novel PI3K degradation by hijacking VHL E3 ubiquitin ligase.
Curcumin protects against manganese-induced neurotoxicity in rat by regulating oxidative stress-related gene expression via H3K27 acetylation.
Fabrication of SA/Gel/C scaffold with 3D bioprinting to generate micro-nano porosity structure for skin wound healing: a detailed animal in vivo study.
Injectable self-healing hydrogel with siRNA delivery property for sustained STING silencing and enhanced therapy of intervertebral disc degeneration.
Role of Lysocardiolipin Acyltransferase in Cigarette Smoke-Induced Lung Epithelial Cell Mitochondrial ROS, Mitochondrial Dynamics, and Apoptosis.
Circular RNA PVT1 inhibits tendon stem/progenitor cell senescence by sponging microRNA-199a-5p.
Dysregulated lipid metabolism blunts the sensitivity of cancer cells to EZH2 inhibitor.
Long Non-coding Antisense RNA DDIT4-AS1 Regulates Meningitic Escherichia coli-Induced Neuroinflammation by Promoting DDIT4 mRNA Stability.
XBP1s promotes the development of lung adenocarcinoma via the p‑JNK MAPK pathway.
Epac activation ameliorates tubulointerstitial inflammation in diabetic nephropathy.
YTHDF2 promotes multiple myeloma cell proliferation via STAT5A/MAP2K2/p-ERK axis.
Nicotinamide N-methyltransferase ameliorates renal fibrosis by its metabolite 1-methylnicotinamide inhibiting the TGF-β1/Smad3 pathway.
Ornithine decarboxylase of the fungal pathogen Colletotrichum higginsianum plays an important role in regulating global metabolic pathways and virulence.
Proteomic analysis reveals that Xbp1s promotes hypoxic pulmonary hypertension through the p-JNK MAPK pathway.
Role of SLC39A6 in the development and progression of liver cancer.
Cordycepin prevents and ameliorates experimental autoimmune encephalomyelitis by inhibiting leukocyte infiltration and reducing neuroinflammation.
Chk1 Inhibition Ameliorates Alzheimer's Disease Pathogenesis and Cognitive Dysfunction Through CIP2A/PP2A Signaling.
LPS Activated Macrophages Induced Hepatocyte Pyroptosis via P2X7R Activation of NLRP3 in Mice.
DECR1 directly activates HSL to promote lipolysis in cervical cancer cells.
C19orf12 ablation causes ferroptosis in mitochondrial membrane protein-associated with neurodegeneration.
Maintaining homeostasis of mitochondria and endoplasmic reticulum with NSC228155 alleviates cisplatin-induced acute kidney injury.
ROS-responsive nanoparticles for oral delivery of luteolin and targeted therapy of ulcerative colitis by regulating pathological microenvironment.
In situ injectable hydrogel-loaded drugs induce anti-tumor immune responses in melanoma immunochemotherapy.
MiR-7-5p suppresses invasion via downregulation of the autophagy-related gene ATG7 and increases chemoresistance to cisplatin in BCa.
Divergence of Tbx4 hindlimb enhancer HLEA underlies the hindlimb loss during cetacean evolution.
Anti-PD-L1 antibody alleviates pulmonary fibrosis by inducing autophagy via inhibition of the PI3K/Akt/mTOR pathway.
Myricetin exerts its antiviral activity against infectious bronchitis virus by inhibiting the deubiquitinating activity of papain-like protease.
Cinnamomi Ramulus inhibits the growth of colon cancer cells via Akt/ERK signaling pathways.
Implications of miR-148a-3p/p35/PTEN signaling in tau hyperphosphorylation and autoregulatory feedforward of Akt/CREB in Alzheimer's disease.
Highly efficient A-to-G base editing by ABE8.17 in rabbits.
LncRNA PVT1 promotes tumorigenesis of glioblastoma by recruiting COPS5 to deubiquitinate and stabilize TRIM24.
Hyperglycemia Promotes Endothelial Cell Senescence through AQR/PLAU Signaling Axis.
RETRACTED: PINK1 deficiency in gastric cancer compromises mitophagy, promotes the Warburg effect, and facilitates M2 polarization of macrophages.
Regulation of chromatin accessibility by hypoxia and HIF.
Skin epithelial cells change their mechanics and proliferation upon snail-mediated EMT signalling.
The SETD8/ELK1/bach1 complex regulates hyperglycaemia-mediated EndMT in diabetic nephropathy.
Construction of a Recombinant Japanese Encephalitis Virus with a Hemagglutinin-Tagged NS2A: A Model for an Analysis of Biological Characteristics and Functions of NS2A during Viral Infection.
SETD8 cooperates with MZF1 to participate in hyperglycemia-induced endothelial inflammation via elevation of WNT5A levels in diabetic nephropathy.
TGF-β1-induced RAP2 regulates invasion in pancreatic cancer.
Highland barley Monascus purpureus Went extract ameliorates high-fat, high-fructose, high-cholesterol diet induced nonalcoholic fatty liver disease by regulating lipid metabolism in golden hamsters.
WWOX-Mediated Degradation of AMOTp130 Negatively Affects Egress of Filovirus VP40 Virus-Like Particles.
Long noncoding RNA Gm31629 protects against mucosal damage in experimental colitis via YB-1/E2F pathway.
NAD(+) Anabolism Disturbance Causes Glomerular Mesangial Cell Injury in Diabetic Nephropathy.
Peroxidase-like Active Nanomedicine with Dual Glutathione Depletion Property to Restore Oxaliplatin Chemosensitivity and Promote Programmed Cell Death.
Co-delivery of EGCG and lycopene via a pickering double emulsion induced synergistic hypolipidemic effect.
Ascorbic acid 2-glucoside preconditioning enhances the ability of bone marrow mesenchymal stem cells in promoting wound healing.
Folic Acid-Modified Fluorescent-Magnetic Nanoparticles for Efficient Isolation and Identification of Circulating Tumor Cells in Ovarian Cancer.
lncRNA HITT inhibits metastasis by attenuating Rab5-mediated endocytosis in lung adenocarcinoma.
An advanced network pharmacology study to explore the novel molecular mechanism of Compound Kushen Injection for treating hepatocellular carcinoma by bioinformatics and experimental verification.
MYCT1 alters the glycogen shunt by regulating selective translation of RACK1-mediated enzymes.
Structures of a deltacoronavirus spike protein bound to porcine and human receptors.
Cancer stem cell regulated phenotypic plasticity protects metastasized cancer cells from ferroptosis.
Novel phosphanegold(I) thiolate complexes suppress de novo lipid synthesis in human lung cancer.
Transition of autophagy and apoptosis in fibroblasts depends on dominant expression of HIF-1α or p53.
ALKBH3-dependent m(1)A demethylation of Aurora A mRNA inhibits ciliogenesis.
Knockdown of long noncoding RNA MIAT attenuates cigarette smoke-induced airway remodeling by downregulating miR-29c-3p-HIF3A axis.
Zinc finger protein 91 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation.
Systematic characterization of the metabolites of defatted walnut powder extract in vivo and screening of the mechanisms against NAFLD by UPLC-Q-Exactive Orbitrap MS combined with network pharmacology.
RKIP Induction Promotes Tumor Differentiation via SOX2 Degradation in NF2-Deficient Conditions.
Tumor Necrosis Factor-α-Induced Protein 8-Like 2 Fosters Tumor-Associated Microbiota to Promote the Development of Colorectal Cancer.
KLF2 mediates the suppressive effect of BDNF on diabetic intimal calcification by inhibiting HK1 induced endothelial-to-mesenchymal transition.
Synchronous Disintegration of Ferroptosis Defense Axis via Engineered Exosome-Conjugated Magnetic Nanoparticles for Glioblastoma Therapy.
Acute Myeloid Leukemia Cells Educate Mesenchymal Stromal Cells toward an Adipogenic Differentiation Propensity with Leukemia Promotion Capabilities.
Circ_0060731 mediated miR-21-5p-PDCD4/ESR1 pathway to induce apoptosis of placental trophoblasts in intrahepatic cholestasis of pregnancy.
Palbociclib regulates intracellular lipids in mammary tumor cells by secreting lipoprotein lipase.
Targeting RPL23 restores chemosensitivity of cisplatin-resistant ovarian carcinoma by inhibiting EMT.
Differential Expression of CB(1) Cannabinoid Receptor and Cannabinoid Receptor Interacting Protein 1a in Labor.
Maternal Prkce expression in mature oocytes is critical for the first cleavage facilitating maternal-to-zygotic transition in mouse early embryos.
Bicyclol alleviates high-fat diet-induced hepatic ER stress- and autophagy-associated non-alcoholic fatty liver disease/non-alcoholic steatohepatitis in mice.
Tetrandrine Ameliorates Traumatic Brain Injury by Regulating Autophagy to Reduce Ferroptosis.
The function and mechanism of dopamine in the activation of CD4(+) T cell.
Osthole inhibits the migration and invasion of highly metastatic breast cancer cells by suppressing ITGα3/ITGβ5 signaling.
LncRNA-6395 promotes myocardial ischemia-reperfusion injury in mice through increasing p53 pathway.
Caffeine Citrate Protects Against Sepsis-Associated Encephalopathy and Inhibits the UCP2/NLRP3 Axis in Astrocytes.
Melatonin Alleviates Liver Fibrosis by Inhibiting Autophagy.
ADH1C Facilitates Cisplatin Resistance of Lung Adenocarcinoma Cells.
Protection of pancreatic β-cell by phosphocreatine through mitochondrial improvement via the regulation of dual AKT/IRS-1/GSK-3β and STAT3/Cyp-D signaling pathways.
HDM induce airway epithelial cell ferroptosis and promote inflammation by activating ferritinophagy in asthma.
Rutin-activated adipose tissue thermogenesis is correlated with increased intestinal short-chain fatty acid levels.
MiR-153 downregulation alleviates PTSD-like behaviors and reduces cell apoptosis by upregulating the Sigma-1 receptor in the hippocampus of rats exposed to single-prolonged stress.
Early environmental enrichment for autism spectrum disorder Fmr1 mice models has positive behavioral and molecular effects.
The anti-angiogenesis mechanism of Geniposide on rheumatoid arthritis is related to the regulation of PTEN.
Alternative splicing of the human rhomboid family-1 gene RHBDF1 inhibits epidermal growth factor receptor activation.
Mammalian PERIOD2 regulates H2A.Z incorporation in chromatin to orchestrate circadian negative feedback.
Lithium attenuates blood-brain barrier damage and brain edema following intracerebral hemorrhage via an endothelial Wnt/β-catenin signaling-dependent mechanism in mice.
Tanshinone IIA inhibits cell growth by suppressing SIX1-induced aerobic glycolysis in non-small cell lung cancer cells.
Proteomic analysis reveals the heterogeneity of metabolic reprogramming in lacrimal gland tumors.
MicroRNA-221-5p Promotes Ricin Toxin-induced Inflammation via PI3K/Akt signaling pathway by targeting COL4a5.
AMG487 inhibits PRRSV replication and ameliorates lung injury in pig lung xenografts by down-regulating the expression of ANXA2.
FAIM regulates autophagy through glutaminolysis in lung adenocarcinoma.
HGF Secreted by Mesenchymal Stromal Cells Promotes Primordial Follicle Activation by Increasing the Activity of the PI3K-AKT Signaling Pathway.
Ephedra herb reduces adriamycin-induced testicular toxicity by upregulating the gonadotropin-releasing hormone signalling pathway.
Naringin suppressed airway inflammation and ameliorated pulmonary endothelial hyperpermeability by upregulating Aquaporin1 in lipopolysaccharide/cigarette smoke-induced mice.
Berberine reduces hepatic ceramide levels to improve insulin resistance in HFD-fed mice by inhibiting HIF-2α.
Abrogation of ARF6 in promoting erastin-induced ferroptosis and mitigating capecitabine resistance in gastric cancer cells.
DR1 Activation Inhibits the Proliferation of Vascular Smooth Muscle Cells through Increasing Endogenous H(2)S in Diabetes.
Effects of 2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione on autophagy and the PI3K/AKT/mTOR signaling pathway in human cholangiocarcinoma QBC939 cells.
SORTING NEXIN2 proteins mediate stomatal movement and the response to drought stress by modulating trafficking and protein levels of the ABA exporter ABCG25.
Dietary curcumin supplementation ameliorates placental inflammation in rats with intra-uterine growth retardation by inhibiting the NF-κB signaling pathway.
Genome-scale CRISPR-Cas9 screen reveals novel regulators of B7-H3 in tumor cells.
Small molecule targeting FOXM1 DNA binding domain exhibits anti-tumor activity in ovarian cancer.
Novel Sphingosine Kinase 1 Inhibitor Suppresses Growth of Solid Tumor and Inhibits the Lung Metastasis of Triple-Negative Breast Cancer.
Recombinant ACE2 protein protects against acute lung injury induced by SARS-CoV-2 spike RBD protein.
Zebrafish Xenograft Model for Studying Pancreatic Cancer-Instructed Innate Immune Microenvironment.
Novel Thermosensitive Hydrogel Promotes Spinal Cord Repair by Regulating Mitochondrial Function.
Structural basis of substrate recognition and translocation by human very long-chain fatty acid transporter ABCD1.
The circadian clock protein Rev-erbα provides neuroprotection and attenuates neuroinflammation against Parkinson's disease via the microglial NLRP3 inflammasome.
Anti-tumor activity of polysaccharides extracted from Pinus massoniana pollen in colorectal cancer- in vitro and in vivo studies.
Overexpression of VPS16 correlates with tumor progression and chemoresistance in colorectal cancer.
Carboxymethyl Chitosan Modified Oxymatrine Liposomes for the Alleviation of Emphysema in Mice via Pulmonary Administration.
C. elegans monitor energy status via the AMPK pathway to trigger innate immune responses against bacterial pathogens.
Extracellular Vesicles-Encapsulated miR-153-3p Potentiate the Survival and Invasion of Lung Adenocarcinoma.
Targeting the SREBP-1/Hsa-Mir-497/SCAP/FASN Oncometabolic Axis Inhibits the Cancer Stem-like and Chemoresistant Phenotype of Non-Small Cell Lung Carcinoma Cells.
The mechanism of dioscin preventing lung cancer based on network pharmacology and experimental validation.
All-trans retinoic acid increases the pathogenicity of the H9N2 influenza virus in mice.
Oncostatin M receptor regulates osteoblast differentiation via extracellular signal-regulated kinase/autophagy signaling.
Salubrinal-mediated activation of eIF2α signaling improves oxidative stress-induced BMSCs senescence and senile osteoporosis.
KDM6B promotes PARthanatos via suppression of O6-methylguanine DNA methyltransferase repair and sustained checkpoint response.
Bisacodyl Limits Chikungunya Virus Replication In Vitro and Is Broadly Antiviral.
Ferroptosis participates in neuron damage in experimental cerebral malaria and is partially induced by activated CD8(+) T cells.
Phloretin ameliorates diabetic nephropathy by inhibiting nephrin and podocin reduction through a non-hypoglycemic effect.
Baicalin alleviates endometrial inflammatory injury through regulation of tight junction proteins.
Probiotic Bifidobacterium breve MCC1274 Mitigates Alzheimer's Disease-Related Pathologies in Wild-Type Mice.
Enhanced autophagy promotes radiosensitivity by mediating Sirt1 downregulation in RM-1 prostate cancer cells.
Inhibition of noncaspase proteases, calpain and proteasome, via ALLN and Bortezomib contributes to cell death through low degradation of pro-/anti-apoptotic proteins and apoptosis induction.
Inhibition of AKT induces p53/SIRT6/PARP1-dependent parthanatos to suppress tumor growth.
Phosphorylation of guanosine monophosphate reductase triggers a GTP-dependent switch from pro- to anti-oncogenic function of EPHA4.
Host Zinc-finger CCHC-type containing protein 3 inhibits pseudorabies virus proliferation by regulating type I interferon signaling.
Integrated analysis of tRNA-derived small RNAs in proliferative human aortic smooth muscle cells.
JNK and Jag1/Notch2 co-regulate CXCL16 to facilitate cypermethrin-induced kidney damage.
Integrated metabolism and epigenetic modifications in the macrophages of mice in responses to cold stress.
SARS-CoV-2 productively infects human brain microvascular endothelial cells.
Inhibition of the lncRNA MIAT prevents podocyte injury and mitotic catastrophe in diabetic nephropathy.
Protective Effects of Liquiritigenin against Cisplatin-Induced Nephrotoxicity via NRF2/SIRT3-Mediated Improvement of Mitochondrial Function.
Resveratrol Induces Autophagy and Apoptosis in Non-Small-Cell Lung Cancer Cells by Activating the NGFR-AMPK-mTOR Pathway.
NCAPH is a prognostic biomarker and associated with immune infiltrates in lung adenocarcinoma.
The role of ER stress and ATP/AMPK in oxidative stress meditated hepatotoxicity induced by citrinin.
High-frequency repetitive transcranial magnetic stimulation mitigates depression-like behaviors in CUMS-induced rats via FGF2/FGFR1/p-ERK signaling pathway.
Large Yellow Tea Extract Ameliorates Metabolic Syndrome by Suppressing Lipogenesis through SIRT6/SREBP1 Pathway and Modulating Microbiota in Leptin Receptor Knockout Rats.
Antioxidant potential of Pediococcus pentosaceus strains from the sow milk bacterial collection in weaned piglets.
Hexokinase 2-mediated glycolysis promotes receptor activator of NF-κB ligand expression in Porphyromonas gingivalis lipopolysaccharide-treated osteoblasts.
miR-520d-3p/MIG-7 axis regulates vasculogenic mimicry formation and metastasis in osteosarcoma.
Sema3A accelerates bone formation during distraction osteogenesis in mice.
Inhibition of nuclear deacetylase Sirtuin-1 induces mitochondrial acetylation and calcium overload leading to cell death.
Dopamine 1 receptors inhibit apoptosis via activating CSE/H(2) S pathway in high glucose-induced vascular endothelial cells.
In utero hypoxia attenuated acetylcholine-mediated vasodilatation via CHRM3/p-NOS3 in fetal sheep MCA: role of ROS/ERK1/2.
Curcumin attenuates isoniazid-induced hepatotoxicity by upregulating the SIRT1/PGC-1α/NRF1 pathway.
PCDHB14 promotes ferroptosis and is a novel tumor suppressor in hepatocellular carcinoma.
Podophyllotoxin-combined 5-aminolevulinic acid photodynamic therapy significantly promotes HR-HPV-infected cell death.
Entacapone alleviates acute kidney injury by inhibiting ferroptosis.
Periostin promotes nucleus pulposus cells apoptosis by activating the Wnt/β-catenin signaling pathway.
Trilobatin promotes angiogenesis after cerebral ischemia-reperfusion injury via SIRT7/VEGFA signaling pathway in rats.
A dual crosslinked hydrogel-mediated integrated peptides and BMSC therapy for myocardial regeneration.
Prognostic and functional role of hyaluronan-binding protein 1 in pancreatic ductal adenocarcinoma.
Inhibition of Drp1 ameliorates diabetic retinopathy by regulating mitochondrial homeostasis.
Inhibition of Cpt1a alleviates oxidative stress-induced chondrocyte senescence via regulating mitochondrial dysfunction and activating mitophagy.
Elevation of N-acetyltransferase 10 in hippocampal neurons mediates depression- and anxiety-like behaviors.
Newcastle disease virus degrades SIRT3 via PINK1-PRKN-dependent mitophagy to reprogram energy metabolism in infected cells.
Amentoflavone attenuates Listeria monocytogenes pathogenicity through an LLO-dependent mechanism.
The neuroprotective effects of GPR55 against hippocampal neuroinflammation and impaired adult neurogenesis in CSDS mice.
Hippocampal AMPA receptors mediate the impairment of spatial learning and memory in prenatally stressed offspring rats.
Dasatinib suppresses atherosclerotic lesions by suppressing cholesterol uptake in a mouse model of hypercholesterolemia.
Discovery of cinnamamide-barbiturate hybrids as a novel class of Nrf2 activator against myocardial ischemia/reperfusion injury.
Targeting chemoresistance in Xp11.2 translocation renal cell carcinoma using a novel polyamide-chlorambucil conjugate.
IL-17A drives cognitive aging probably via inducing neuroinflammation and theta oscillation disruption in the hippocampus.
Thiamine pretreatment improves endotoxemia-related liver injury and cholestatic complications by regulating galactose metabolism and inhibiting macrophage activation.
Pemafibrate attenuates pulmonary fibrosis by inhibiting myofibroblast differentiation.
Perilipin 5 protects against oxygen-glucose deprivation/reoxygenation-elicited neuronal damage by inhibiting oxidative stress and inflammatory injury via the Akt-GSK-3β-Nrf2 pathway.
Cellular protein HSC70 promotes fowl adenovirus serotype 4 replication in LMH cells via interacting with viral 100K protein.
Effect of starvation and refeeding on reactive oxygen species, autophagy and oxidative stress in Chinese perch (Siniperca chuatsi) muscle growth.
Gallic acid induces T-helper-1-like T(reg) cells and strengthens immune checkpoint blockade efficacy.
Induction of endothelial barrier dysfunction by serum factors in rats subjected to traumatic brain injury and hemorrhagic shock.
LncRNA HOTTIP PROMOTES OVARIAN CANCER CELL INVASION AND METASTASIS BY STABILIZING HIF-1α IN THE ANOXIC CELLULAR MICROENVIRONMENT.
Gankyrin modulated non-small cell lung cancer progression via glycolysis metabolism in a YAP1-dependent manner.
Hypoxia-Induced Scleral HIF-2α Upregulation Contributes to Rises in MMP-2 Expression and Myopia Development in Mice.
PFKM inhibits doxorubicin-induced cardiotoxicity by enhancing oxidative phosphorylation and glycolysis.
Duck Tembusu virus infection induces mitochondrial-mediated and death receptor-mediated apoptosis in duck embryo fibroblasts.
Transcriptional landscape of human neuroblastoma cells in response to SARS-CoV-2.
Targeting BCAT1 Combined with α-Ketoglutarate Triggers Metabolic Synthetic Lethality in Glioblastoma.
Human chorion-derived mesenchymal stem cells suppress JAK2/STAT3 signaling and induce apoptosis of cholangiocarcinoma cell lines.
20(S)-Protopanaxadiol decreases atherosclerosis in ApoE KO mice by increasing the levels of LDLR and inhibiting its binding with PCSK9.
Akkermansia muciniphila Colonization Alleviating High Fructose and Restraint Stress-Induced Jejunal Mucosal Barrier Disruption.
Cholesterol sulfate alleviates ulcerative colitis by promoting cholesterol biosynthesis in colonic epithelial cells.
LncRNA ANRIL mediates endothelial dysfunction through BDNF downregulation in chronic kidney disease.
Pseudoislet Aggregation of Pancreatic β-Cells Improves Glucose Stimulated Insulin Secretion by Altering Glucose Metabolism and Increasing ATP Production.
Dabie bandavirus Nonstructural Protein Interacts with Actin to Induce F-Actin Rearrangement and Inhibit Viral Adsorption and Entry.
Effects of Artemisinin on Escherichia coli-Induced Mastitis in Bovine Mammary Epithelial Cells and Mice.
HDAC2- and EZH2-Mediated Histone Modifications Induce PDK1 Expression through miR-148a Downregulation in Breast Cancer Progression and Adriamycin Resistance.
Enhancement of Osteoblast Function through Extracellular Vesicles Derived from Adipose-Derived Stem Cells.
Prefrontal GABA(A)(δ)R Promotes Fear Extinction through Enabling the Plastic Regulation of Neuronal Intrinsic Excitability.
GRP75-driven, cell-cycle-dependent macropinocytosis of Tat/pDNA-Ca(2+) nanoparticles underlies distinct gene therapy effect in ovarian cancer.
Thiostrepton induces ferroptosis in pancreatic cancer cells through STAT3/GPX4 signalling.
The E3 ubiquitin ligase MG53 inhibits hepatocellular carcinoma by targeting RAC1 signaling.
β-Caryophyllene suppresses ferroptosis induced by cerebral ischemia reperfusion via activation of the NRF2/HO-1 signaling pathway in MCAO/R rats.
Bisdemethoxycurcumin Attenuated Renal Injury via Activation of Keap1/Nrf2 Pathway in High-Fat Diet-Fed Mice.
Pseudorabies Virus Tegument Protein UL13 Suppresses RLR-Mediated Antiviral Innate Immunity through Regulating Receptor Transcription.
N-glycosylation of GDF15 abolishes its inhibitory effect on EGFR in AR inhibitor-resistant prostate cancer cells.
Viral evasion of PKR restriction by reprogramming cellular stress granules.
Proteomic Mapping and Targeting of Mitotic Pericentriolar Material in Tumors Bearing Centrosome Amplification.
Iron deficiency exacerbates aortic medial degeneration by inducing excessive mitochondrial fission.
Nicotinamide mononucleotide supplementation protects the intestinal function in aging mice and D-galactose induced senescent cells.
Effect of Qingyangshen glycosides on social defeat mice model.
Sulfate oligosaccharide of Gracilaria lemaneiformis modulates type 1 immunity by restraining T cell activation.
The role of ciliopathy-associated type 3 adenylyl cyclase in infanticidal behavior in virgin adult male mice.
N6-methyladenosine RNA demethylase ALKBH5 is testis-specifically downregulated in hybrid male sterile dzo and is a target gene of bta-miR-200a.
Monitoring Protein Import into the Endoplasmic Reticulum in Living Cells with Proximity Labeling.
KIFC3 promotes proliferation, migration and invasion of esophageal squamous cell carcinoma cells by activating EMT and β-catenin signaling.
CCL20/CCR6 axis mediates macrophages to promote proliferation and migration of ESCs by blocking autophagic flux in endometriosis.
Structure-Based Discovery of a Series of NSD2-PWWP1 Inhibitors.
Chronic stress-induced depression requires the recruitment of peripheral Th17 cells into the brain.
ZEB2/TWIST1/PRMT5/NuRD Multicomplex Contributes to the Epigenetic Regulation of EMT and Metastasis in Colorectal Carcinoma.
FUBP3 Degrades the Porcine Epidemic Diarrhea Virus Nucleocapsid Protein and Induces the Production of Type I Interferon.
Nonstructural Protein NSs Activates Inflammasome and Pyroptosis through Interaction with NLRP3 in Human Microglial Cells Infected with Severe Fever with Thrombocytopenia Syndrome Bandavirus.
Quantitative proteomic analysis of Bi Zhong Xiao decoction against collagen-induced arthritis rats in the early and late stages.
Transient neuroinflammation following surgery contributes to long-lasting cognitive decline in elderly rats via dysfunction of synaptic NMDA receptor.
Mitochondrial Calcium-Triggered Oxidative Stress and Developmental Defects in Dopaminergic Neurons Differentiated from Deciduous Teeth-Derived Dental Pulp Stem Cells with MFF Insufficiency.
PRIM2 Promotes Cell Cycle and Tumor Progression in p53-Mutant Lung Cancer.
TFRC upregulation promotes ferroptosis in CVB3 infection via nucleus recruitment of Sp1.
Blocking glycine utilization inhibits multiple myeloma progression by disrupting glutathione balance.
SULF2 enhances GDF15-SMAD axis to facilitate the initiation and progression of pancreatic cancer.
Combined exposure of lead and high-fat diet enhanced cognitive decline via interacting with CREB-BDNF signaling in male rats.
Interleukin 7 inhibit autophagy via P53 regulated AMPK/mTOR signaling pathway in non-small cell lung cancer.
Activated AXL Protects Against Hepatic Ischemia-reperfusion Injury by Upregulating SOCS-1 Expression.
Knockdown of GBP1 inhibits BCG-induced apoptosis in macrophage RAW 264.7 cells via p38/JNK pathway.
Rosmarinic Acid Decreases the Malignancy of Pancreatic Cancer Through Inhibiting Gli1 Signaling.
Moringa oleifera Lam. seed extract protects kidney function in rats with diabetic nephropathy by increasing GSK-3β activity and activating the Nrf2/HO-1 pathway.
Ciliary Type III Adenylyl Cyclase in the VMH Is Crucial for High-Fat Diet-Induced Obesity Mediated by Autophagy.
Ror2 mediates chronic post-thoracotomy pain by inducing the transformation of A1/A2 reactive astrocytes in rats.
Galactose-decorated liver tumor-specific nanoliposomes incorporating selective BRD4-targeted PROTAC for hepatocellular carcinoma therapy.
Resveratrol Improves Synaptic Plasticity in Hypoxic-Ischemic Brain Injury in Neonatal Mice via Alleviating SIRT1/NF-κB Signaling-Mediated Neuroinflammation.
Inflammatory cell-derived CXCL3 promotes pancreatic cancer metastasis through a novel myofibroblast-hijacked cancer escape mechanism.
A calcium phosphate drug carrier loading with 5-fluorouracil achieving a synergistic effect for pancreatic cancer therapy.
Exosomes from dental pulp cells attenuate bone loss in mouse experimental periodontitis.
Sorafenib attenuates liver fibrosis by triggering hepatic stellate cell ferroptosis via HIF-1α/SLC7A11 pathway.
Sestrin2 induction contributes to anti-inflammatory responses and cell survival by globular adiponectin in macrophages.
SIRT1 induces the accumulation of TAMs at colorectal cancer tumor sites via the CXCR4/CXCL12 axis.
The double-edged sword role of TGF-β signaling pathway between intrauterine inflammation and cranial neural crest development.
Alnustone inhibits the growth of hepatocellular carcinoma via ROS- mediated PI3K/Akt/mTOR/p70S6K axis.
Inhibition of progesterone receptor membrane component-1 exacerbates neonatal hypoxic-ischemic cerebral damage in male mice.
ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1.
The deubiquitinase USP28 stabilizes the expression of RecQ family helicases and maintains the viability of triple negative breast cancer cells.
Electroacupuncture alleviates spatial memory deficits in METH withdrawal mice by enhancing astrocyte-mediated glutamate clearance in the dCA1.
Bcl-2 hijacks the arsenic trioxide resistance in SH-SY5Y cells.
Immunoproteasome modulates NLRP3 inflammasome-mediated neuroinflammation under cerebral ischaemia and reperfusion conditions.
C1632 suppresses the migration and proliferation of non-small-cell lung cancer cells involving LIN28 and FGFR1 pathway.
Caveolin-1 negatively regulates inflammation and fibrosis in silicosis.
The critical role of B4GALT4 in promoting microtubule spindle assembly in HCC through the regulation of PLK1 and RHAMM expression.
Role and mechanism of the Dectin-1-mediated Syk/NF-κB signaling pathway in Talaromyces marneffei infection.
Zinc-finger protein 750 mitigates malignant biological behavior of oral CSC-like cells enriched from parental CAL-27 cells.
DNMT3B regulates proliferation of A549 cells through the microRNA-152-3p/NCAM1 pathway.
Deubiquitinase USP13 promotes the epithelial-mesenchymal transition and metastasis in gastric cancer by maintaining Snail protein.
Topical retinoic acid induces corneal strengthening by upregulating transglutaminase 2 in murine cornea.
Morphological changes of macrophages and their potential contribution to tendon healing.
MICAL1 inhibits colorectal cancer cell migration and proliferation by regulating the EGR1/β-catenin signaling pathway.
METTL3 Regulates Liver Homeostasis, Hepatocyte Ploidy, and Circadian Rhythm-Controlled Gene Expression in Mice.
Pyridoxamine ameliorates methylglyoxal-induced macrophage dysfunction to facilitate tissue repair in diabetic wounds.
RNF2 promotes the progression of colon cancer by regulating ubiquitination and degradation of IRF4.
Carrier-Free Delivery of Ultrasmall π-Conjugated Oligomer Nanoparticles with Photothermal Conversion over 80% for Cancer Theranostics.
Silencing TXNIP ameliorates high uric acid-induced insulin resistance via the IRS2/AKT and Nrf2/HO-1 pathways in macrophages.
Silent information regulator 1 ameliorates oxidative stress injury via PGC-1α/PPARγ-Nrf2 pathway after ischemic stroke in rat.
Mettl3 inhibits the apoptosis and autophagy of chondrocytes in inflammation through mediating Bcl2 stability via Ythdf1-mediated m(6)A modification.
Overexpression of DOCK6 in oral squamous cell cancer promotes cellular migration and invasion and is associated with poor prognosis.
Injectable hyaluronic acid hydrogel loaded with BMSC and NGF for traumatic brain injury treatment.
Characterization and function of mandarin fish c-Myc during viral infection process.
Lysyl oxidase promotes anaplastic thyroid carcinoma cell proliferation and metastasis mediated via BMP1.
Cotargeting of Bcl-2 and Mcl-1 shows promising antileukemic activity against AML cells including those with acquired cytarabine resistance.
BPIFA2 as a Novel Early Biomarker to Identify Fatal Radiation Injury After Radiation Exposure.
Effect of Ultraviolet B Irradiation on Melanin Content Accompanied by the Activation of p62/GATA4-Mediated Premature Senescence in HaCaT Cells.
Enhancement of Acylcarnitine Levels in Small Intestine of Abdominal Irradiation Rats Might Relate to Fatty Acid β-Oxidation Pathway Disequilibration.
HSP90AB1 Promotes the Proliferation, Migration, and Glycolysis of Head and Neck Squamous Cell Carcinoma.
Spinal 5-HT(2A) receptor is involved in electroacupuncture inhibition of chronic pain.
A virulence factor as a therapeutic: the probiotic Enterococcus faecium SF68 arginine deiminase inhibits innate immune signaling pathways.
ROS/PI3K/Akt and Wnt/β-catenin signalings activate HIF-1α-induced metabolic reprogramming to impart 5-fluorouracil resistance in colorectal cancer.
ERK/p38/ROS burst responses to environmentally relevant concentrations of diphenyl phosphate-evoked neutrophil extracellular traps formation: Assessing the role of autophagy.
CHMFL-BMX-078, a BMX inhibitor, overcomes the resistance of melanoma to vemurafenib via inhibiting AKT pathway.
High salt activates p97 to reduce host antiviral immunity by restricting Viperin induction.
Novel 5-fluorouracil sensitizers for colorectal cancer therapy: Design and synthesis of S1P receptor 2 (S1PR2) antagonists.
SIRT6 protects vascular smooth muscle cells from osteogenic transdifferentiation via Runx2 in chronic kidney disease.
Urolithin A protects dopaminergic neurons in experimental models of Parkinson's disease by promoting mitochondrial biogenesis through the SIRT1/PGC-1α signaling pathway.
The association of telomere maintenance and TERT expression with susceptibility to human papillomavirus infection in cervical epithelium.
m6A modifications regulate intestinal immunity and rotavirus infection.
Metastasis suppressor 1 controls osteoblast differentiation and bone homeostasis through regulating Src-Wnt/β-catenin signaling.
Saponins from Nigella glandulifera seeds attenuate collagen-induced rheumatoid arthritis in rats via the OPG/RANKL/NF-κB and Ang/Tie-2 pathways.
Guizhi-Shaoyao-Zhimu decoction attenuates monosodium urate crystal-induced inflammation through inactivation of NF-κB and NLRP3 inflammasome.
The ethanol extract of flower buds of Tussilago farfara L. attenuates cigarette smoke-induced lung inflammation through regulating NLRP3 inflammasome, Nrf2, and NF-κB.
A Novel Rat Model of Dry Eye Induced by Aerosol Exposure of Particulate Matter.
Ketogenic diet ameliorates lipid dysregulation in type 2 diabetic mice by downregulating hepatic pescadillo 1.
CBX4-dependent regulation of HDAC3 nuclear translocation reduces Bmp2-induced osteoblastic differentiation and calcification in adamantinomatous craniopharyngioma.
Hyaluronic Acid-Modified Nanoparticles Self-Assembled from Linoleic Acid-Conjugated Chitosan for the Codelivery of miR34a and Doxorubicin in Resistant Breast Cancer.
Long non-coding RNA lncC11orf54-1 modulates neuroinflammatory responses by activating NF-κB signaling during meningitic Escherichia coli infection.
Ginsenoside compound K acts via LRP1 to alleviate Amyloid β(42)-induced neuroinflammation in microglia by suppressing NF-κB.
Actin nucleator formins regulate the tension-buffering function of caveolin-1.
LINC01119 negatively regulates osteogenic differentiation of mesenchymal stem cells via the Wnt pathway by targeting FZD4.
Steroid-sensitive nephrotic syndrome candidate gene CLVS1 regulates podocyte oxidative stress and endocytosis.
Role of Sleep Restriction in Daily Rhythms of Expression of Hypothalamic Core Clock Genes in Mice.
Structure and transport mechanism of the human cholesterol transporter ABCG1.
The Mitochondrial PHB2/OMA1/DELE1 Pathway Cooperates with Endoplasmic Reticulum Stress to Facilitate the Response to Chemotherapeutics in Ovarian Cancer.
Integrative bioinformatics and experimental analysis revealed TEAD as novel prognostic target for hepatocellular carcinoma and its roles in ferroptosis regulation.
Modular assembly of the principal microtubule nucleator γ-TuRC.
SARS-CoV-2 NSP5 and N protein counteract the RIG-I signaling pathway by suppressing the formation of stress granules.
Sodium hydrosulfide reverses β(2)-microglobulin-induced depressive-like behaviors of male Sprague-Dawley rats: Involving improvement of synaptic plasticity and enhancement of Warburg effect in hippocampus.
Salubrinal protects against inflammatory response in macrophage and attenuates psoriasiform skin inflammation by antagonizing NF-κB signaling pathway.
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone provokes progression from chronic pancreatitis to pancreatic intraepithelial neoplasia.
Pyk2 suppresses contextual fear memory in an autophosphorylation-independent manner.
Benzaldehyde Attenuates the Fifth Stage Larval Excretory-Secretory Product of Angiostrongylus cantonensis-Induced Injury in Mouse Astrocytes via Regulation of Endoplasmic Reticulum Stress and Oxidative Stress.
Epimedium protects against dyszoospermia in mice with Pex3 knockout by exerting antioxidant effects and regulating the expression level of P16.
PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells by phosphorylating PRAS40.
Extracellular vesicles from adipose-derived stem cells promote microglia M2 polarization and neurological recovery in a mouse model of transient middle cerebral artery occlusion.
Pulsed electromagnetic field alleviates synovitis and inhibits the NLRP3/Caspase-1/GSDMD signaling pathway in osteoarthritis rats.
4,5-Dimethoxycanthin-6-one is a novel LSD1 inhibitor that inhibits proliferation of glioblastoma cells and induces apoptosis and pyroptosis.
PDGF-D-PDGFRβ signaling enhances IL-15-mediated human natural killer cell survival.
Genome-wide CRISPR/Cas9 library screen identifies PCMT1 as a critical driver of ovarian cancer metastasis.
The amino acids of Autographa californica multiple nucleopolyhedrovirus P48 critical for the association with Ac93 are important for the nuclear egress of nucleocapsids and efficient formation of intranuclear microvesicles.
Ellagic acid ameliorates paraquat-induced liver injury associated with improved gut microbial profile.
Identification of G protein-coupled receptor 55 (GPR55) as a target of curcumin.
The PERK/PKR-eIF2α Pathway Negatively Regulates Porcine Hemagglutinating Encephalomyelitis Virus Replication by Attenuating Global Protein Translation and Facilitating Stress Granule Formation.
Extracellular vesicles derived from glioblastoma promote proliferation and migration of neural progenitor cells via PI3K-Akt pathway.
The Effects of Intraoperative Hypothermia on Postoperative Cognitive Function in the Rat Hippocampus and Its Possible Mechanisms.
Selenium Induces Pancreatic Cancer Cell Death Alone and in Combination with Gemcitabine.
Anti-tumor effect of Yanggan Huayu granule by inducing AKT-mediated apoptosis in hepatocellular carcinoma.
Tanshinone IIA alleviates NLRP3 inflammasome-mediated pyroptosis in Mycobacterium tuberculosis-(H37Ra-) infected macrophages by inhibiting endoplasmic reticulum stress.
Xiaoyao powder improves endometrial receptivity via VEGFR-2-mediated angiogenesis through the activation of the JNK and P38 signaling pathways.
Overexpression of Lin28a induces a primary ovarian insufficiency phenotype via facilitation of primordial follicle activation in mice.
Ligature induced periodontitis in rats causes gut dysbiosis leading to hepatic injury through SCD1/AMPK signalling pathway.
Role of notch signaling pathway in Muc5ac secretion induced by atmospheric PM(2.5) in rats.
PTP70-2, a novel polysaccharide from Polygala tenuifolia, prevents neuroinflammation and protects neurons by suppressing the TLR4-mediated MyD88/NF-κB signaling pathway.
Agrimoniin sensitizes pancreatic cancer to apoptosis through ROS-mediated energy metabolism dysfunction.
Sleeve gastrectomy suppresses hepatic de novo cholesterogenesis and improves hepatic cholesterol accumulation in obese rats with type 2 diabetes mellitus.
Transgelin-2 interacts with CD44 to regulate Notch1 signaling pathway and participates in colorectal cancer proliferation and migration.
NPC1-regulated dynamic of clathrin-coated pits is essential for viral entry.
Notch activation suppresses endothelial cell migration and sprouting via miR-223-3p targeting Fbxw7.
The IFN-inducible GTPase IRGB10 regulates viral replication and inflammasome activation during influenza A virus infection in mice.
Benchmarking a highly selective USP30 inhibitor for enhancement of mitophagy and pexophagy.
Induction of estrogen receptor β-mediated autophagy sensitizes breast cancer cells to TAD1822-7, a novel biphenyl urea taspine derivative.
PDCD4 Simultaneously Promotes Microglia Activation via PDCD4-MAPK-NF-κB Positive Loop and Facilitates Neuron Apoptosis During Neuroinflammation.
Methylene blue prevents osteoarthritis progression and relieves pain in rats via upregulation of Nrf2/PRDX1.
An IgD-Fc-Ig fusion protein restrains the activation of T and B cells by inhibiting IgD-IgDR-Lck signaling in rheumatoid arthritis.
Ginsenoside Rb1 alleviates diabetic kidney podocyte injury by inhibiting aldose reductase activity.
Malic enzyme 2 maintains protein stability of mutant p53 through 2-hydroxyglutarate.
Establishment of a pseudovirus neutralization assay based on SARS-CoV-2 S protein incorporated into lentiviral particles.
Estrogen receptor beta increases clear cell renal cell carcinoma stem cell phenotype via altering the circPHACTR4/miR-34b-5p/c-Myc signaling.
Spindle pole body component 24 homolog potentiates tumor progression via regulation of SRY-box transcription factor 2 in clear cell renal cell carcinoma.
Activation of PGC-1α via isoliquiritigenin-induced downregulation of miR-138-5p alleviates nonalcoholic fatty liver disease.
Exogenous melatonin prevents type 1 diabetes mellitus-induced bone loss, probably by inhibiting senescence.
Neuroglobin expression and function in the temporal cortex of bilirubin encephalopathy rats.
Cryo-EM structure of mouse TRPML2 in lipid nanodiscs.
Differential expression of long non-coding RNAs in the hippocampus of mice exposed to PM(2.5) in Dalian, China.
G protein-coupled receptor 17 restricts rabies virus replication via BAK-mediated apoptosis.
Cinnamic Aldehyde, the main monomer component of Cinnamon, exhibits anti-inflammatory property in OA synovial fibroblasts via TLR4/MyD88 pathway.
Cancer-cell-derived GABA promotes β-catenin-mediated tumour growth and immunosuppression.
The volume-regulated anion channel LRRC8C suppresses T cell function by regulating cyclic dinucleotide transport and STING-p53 signaling.
Mesenchymal stem cell-derived exosome mediated long non-coding RNA KLF3-AS1 represses autophagy and apoptosis of chondrocytes in osteoarthritis.
Role of TGF-β1 in Fluoride-Treated Osteoblasts at Different Stages.
Zinc Protects against Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in TM3 Leydig Cells.
Assessing Mitochondrial DNA Release into the Cytosol and Subsequent Activation of Innate Immune-related Pathways in Mammalian Cells.
Survivin suppression heightens BZML-induced mitotic catastrophe to overcome multidrug resistance by removing therapy-induced senescent A549/Taxol cells.
MxB inhibits long interspersed element type 1 retrotransposition.
miRNA-338-3p inhibits glioma cell proliferation and progression by targeting MYT1L.
The histone deacetylase inhibitor belinostat ameliorates experimental autoimmune encephalomyelitis in mice by inhibiting TLR2/MyD88 and HDAC3/ NF-κB p65-mediated neuroinflammation.
Anti-Inflammatory and Anti-Oxidant Activity of Ultra-Short Wave Diathermy on LPS-Induced Rat Lung Injury.
OLFM4 depletion sensitizes gallbladder cancer cells to cisplatin through the ARL6IP1/caspase-3 axis.
IL-22 Downregulates Peptidylarginine Deiminase-1 in Human Keratinocytes: Adding Another Piece to the IL-22 Puzzle in Epidermal Barrier Formation.
Sodium butyrate alleviates pre-eclampsia in pregnant rats by improving the gut microbiota and short-chain fatty acid metabolites production.
Pleckstrin homology-like domain family A, member 3, a miR-19a-3p-regulated gene, suppresses tumor growth in osteosarcoma by downregulating the Akt pathway.
Salvianolic acid B alleviates diabetic endothelial and mitochondrial dysfunction by down-regulating apoptosis and mitophagy of endothelial cells.
Vibrio harveyi infections induce production of proinflammatory cytokines in murine peritoneal macrophages via activation of p38 MAPK and NF-κB pathways, but reversed by PI3K/AKT pathways.
Persistent high glucose induced EPB41L4A-AS1 inhibits glucose uptake via GCN5 mediating crotonylation and acetylation of histones and non-histones.
Paclitaxel-based supramolecular hydrogel loaded with mifepristone for the inhibition of breast cancer metastasis.
One-Step Synthesis of Multifunctional Chitosan Hydrogel for Full-Thickness Wound Closure and Healing.
Sodium houttuynia alleviates airway inflammation in asthmatic mice by regulating FoxP3/RORγT expression and reversing Treg/Th17 cell imbalance.
MiR-29b-1-5p regulates the proliferation and differentiation of chicken primary myoblasts and analysis of its effective targets.
ATF6-Mediated Unfolded Protein Response Facilitates Adeno-associated Virus 2 (AAV2) Transduction by Releasing the Suppression of the AAV Receptor on Endoplasmic Reticulum Stress.
The spliceosome component Usp39 controls B cell development by regulating immunoglobulin gene rearrangement.
Staphylococcus aureus mediates pyroptosis in bovine mammary epithelial cell via activation of NLRP3 inflammasome.
AQP4 Attenuated TRAF6/NFκB Activation in Acrylamide-Induced Neurotoxicity.
Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance.
Heterozygous FMN2 missense variant found in a family case of premature ovarian insufficiency.
MYSM1 induces apoptosis and sensitizes TNBC cells to cisplatin via RSK3-phospho-BAD pathway.
Changes of flavin-containing monooxygenases and trimethylamine-N-oxide may be involved in the promotion of non-alcoholic fatty liver disease by intestinal microbiota metabolite trimethylamine.
Norepinephrine promotes glioma cell migration through up-regulating the expression of Twist1.
Circular RNA circSHPRH inhibits the malignant behaviors of bladder cancer by regulating the miR-942/BARX2 pathway.
Comprehensive Analysis of Protein Acetylation and Glucose Metabolism in Mouse Brains Infected with Rabies Virus.
Neuroprotection of chicoric acid in a mouse model of Parkinson's disease involves gut microbiota and TLR4 signaling pathway.
Employing CRISPR-Cas9 to Generate CD133 Synthetic Lethal Melanoma Stem Cells.
The deubiquitinating enzyme USP20 regulates the stability of the MCL1 protein.
PINK1-parkin-mediated neuronal mitophagy deficiency in prion disease.
Overexpressed mitogen-and stress-activated protein kinase 1 promotes the resistance of cytarabine in acute myeloid leukemia through brahma related gene 1-mediated upregulation of heme oxygenase-1.
Synthesis and biological evaluation of aminobenzamides containing purine moiety as class I histone deacetylases inhibitors.
Asprosin induces vascular endothelial-to-mesenchymal transition in diabetic lower extremity peripheral artery disease.
Themis is indispensable for IL-2 and IL-15 signaling in T cells.
Novel stress granule-like structures are induced via a paracrine mechanism during viral infection.
Programmed death-ligand 1 signaling and expression are reversible by lycopene via PI3K/AKT and Raf/MEK/ERK pathways in tongue squamous cell carcinoma.
Chicoric Acid Prevents Neuroinflammation and Neurodegeneration in a Mouse Parkinson's Disease Model: Immune Response and Transcriptome Profile of the Spleen and Colon.
ZHX2 inhibits thyroid cancer metastasis through transcriptional inhibition of S100A14.
A Second Near-Infrared Ru(II) Polypyridyl Complex for Synergistic Chemo-Photothermal Therapy.
Structural Optimization and Structure-Activity Relationship Studies of 6,6-Dimethyl-4-(phenylamino)-6H-pyrimido[5,4-b][1,4]oxazin-7(8H)-one Derivatives as A New Class of Potent Inhibitors of Pan-Trk and Their Drug-Resistant Mutants.
Discovery of 3,4-Dihydrobenzo[f][1,4]oxazepin-5(2H)-one Derivatives as a New Class of Selective TNIK Inhibitors and Evaluation of Their Anti-Colorectal Cancer Effects.
Anti-proliferation and anti-inflammation effects of corilagin in rheumatoid arthritis by downregulating NF-κB and MAPK signaling pathways.
Physiological and transcriptomic analyses reveal the toxicological mechanism and risk assessment of environmentally-relevant waterborne tetracycline exposure on the gills of tilapia (Oreochromis niloticus).
Berberine inhibits gastric cancer development and progression by regulating the JAK2/STAT3 pathway and downregulating IL-6.
Silk fibroin nanofibrous scaffolds incorporated with microRNA-222 loaded chitosan nanoparticles for enhanced neuronal differentiation of neural stem cells.
Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis.
PRSS2 overexpression relates to poor prognosis and promotes proliferation, migration and invasion in gastric cancer.
Integrated bioinformatics analysis and screening of hub genes in polycystic ovary syndrome.
CircCERS6 Suppresses the Development of Epithelial Ovarian Cancer Through Mediating miR-630/RASSF8.
Yiqi Huoxue Tongluo recipe regulates NR4A1 to improve renal mitochondrial function in unilateral ureteral obstruction (UUO) rats.
Catalpol relieved angiotensin II-induced blood-brain barrier destruction via inhibiting the TLR4 pathway in brain endothelial cells.
Aspirin relieves the calcification of aortic smooth muscle cells by enhancing the heat shock response.
Study on the biological mechanism of urolithin a on nasopharyngeal carcinoma in vitro.
Louki Zupa decoction attenuates the airway inflammation in acute asthma mice induced by ovalbumin through IL-33/ST2-NF-κB/GSK3β/mTOR signalling pathway.
Structure and biological evaluation of Caenorhabditis elegans CISD-1/mitoNEET, a KLP-17 tail domain homologue, supports attenuation of paraquat-induced oxidative stress through a p38 MAPK-mediated antioxidant defense response.
FUS Mutation Causes Disordered Lipid Metabolism in Skeletal Muscle Associated with ALS.
circSKIL promotes osteoblastic differentiation of periodontal ligament cells by sponging miR-532-5p to activate Notch signaling.
Knockdown of ZBTB11 impedes R-loop elimination and increases the sensitivity to cisplatin by inhibiting DDX1 transcription in bladder cancer.
Periostin contributes to the adventitial remodeling of atherosclerosis by activating adventitial fibroblasts.
Dissection of cellular and molecular mechanisms of aristolochic acid-induced hepatotoxicity via single-cell transcriptomics.
PEDF inhibits non‑small cell lung cancer proliferation by suppressing autophagy through downregulation of AMPK‑ULK1 signaling.
The LINC00152/miR-205-5p/CXCL11 axis in hepatocellular carcinoma cancer-associated fibroblasts affects cancer cell phenotypes and tumor growth.
DNASE1L3 inhibits hepatocellular carcinoma by delaying cell cycle progression through CDK2.
CircRNA-001241 mediates sorafenib resistance of hepatocellular carcinoma cells by sponging miR-21-5p and regulating TIMP3 expression.
Yanghe decoction attenuated pain hypersensitivity induced by michigan cancer foundation-7 injection in rats with bone metastases from breast cancer by inhibiting transient receptor potential ankyrin 1.
A homogalacturonan from Lonicera japonica Thunb. disrupts angiogenesis via epidermal growth factor receptor and Delta-like 4 associated signaling.
Photobiomodulation effects in metalloproteinases expression in zymosan-induced arthritis.
3-Arylcoumarin inhibits vascular calcification by inhibiting the generation of AGEs and anti-oxidative stress.
Effects of bicyclol on hepatic sinusoidal obstruction syndrome induced by Gynura segetum.
Flavonoid extract of saffron by-product alleviates hyperuricemia via inhibiting xanthine oxidase and modulating gut microbiota.
Andrographolide suppresses breast cancer progression by modulating tumor-associated macrophage polarization through the Wnt/β-catenin pathway.
Expression and significance of let-7a and tumor necrosis factor-alpha in placenta of severe preeclampsia.
Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia.
Androgen receptor suppresses β-adrenoceptor-mediated CREB activation and thermogenesis in brown adipose tissue of male mice.
A recombinant scFv antibody-based fusion protein that targets EGFR associated with IMPDH2 downregulation and its drug conjugate show therapeutic efficacy against esophageal cancer.
HIV-1 Tat drives the Fabp4/NF-κB feedback loop in microglia to mediate inflammatory response and neuronal apoptosis.
Enhancement of astrocytic gap junctions Connexin43 coupling can improve long-term isoflurane anesthesia-mediated brain network abnormalities and cognitive impairment.
KDM6B cooperates with Tau and regulates synaptic plasticity and cognition via inducing VGLUT1/2.
c-Myc plays a critical role in the antileukemic activity of the Mcl-1-selective inhibitor AZD5991 in acute myeloid leukemia.
FBXL6 depletion restrains clear cell renal cell carcinoma progression.
Hsp90 Inhibitor STA9090 induced VPS35 related extracellular vesicle release and metastasis in hepatocellular carcinoma.
miR‑141 impairs mitochondrial function in cardiomyocytes subjected to hypoxia/reoxygenation by targeting Sirt1 and MFN2.
Network pharmacology and molecular docking analysis on molecular targets and mechanisms of Gastrodia elata Blume in the treatment of ischemic stroke.
Pseudogene CSPG4P12 affects the biological behavior of non‑small cell lung cancer by Bcl‑2/Bax mitochondrial apoptosis pathway.
NSUN5 promotes progression and predicts poor prognosis in hepatocellular carcinoma.
The Mechano-Ubiquitinome of Articular Cartilage: Differential Ubiquitination and Activation of a Group of ER-Associated DUBs and ER Stress Regulators.
Efficient reprogramming of human fibroblasts using RNA reprogramming with DAPT and iDOT1L under normoxia conditions.
Polydopamine-mediated graphene oxide and nanohydroxyapatite-incorporated conductive scaffold with an immunomodulatory ability accelerates periodontal bone regeneration in diabetes.
Сyclooxygenase-2 Inhibitor Parecoxib Reduces LPS-Induced Activation of BV2 Microglia Cells.
Oxidative phosphorylation regulates interleukin-10 production in regulatory B cells via the extracellular signal-related kinase pathway.
Rifaximin protects against circadian rhythm disruption-induced cognitive impairment through preventing gut barrier damage and neuroinflammation.
Targeted lipidomics analysis of lysine 179 acetylation of ACSF2 in rat hepatic stellate cells.
Clitoria ternatea blue petal extract protects against obesity, oxidative stress, and inflammation induced by a high-fat, high-fructose diet in C57BL/6 mice.
Facile discovery of red blood cell deformation and compromised membrane/skeleton assembly in Prader-Willi syndrome.
R158Q and G212S, novel pathogenic compound heterozygous variants in SLC12A3 of Gitelman syndrome.
Hyaluronic acids mediate the infiltration, migration, and M2 polarization of macrophages: evaluating metabolic molecular phenotypes in gliomas.
The transcription factor KLF14 attenuates LPS-induced acute lung injury by ameliorating apoptosis of alveolar epithelial cells in mice.
The mechanism underlying ICAM-1 and E-selectin-mediated hypertriglyceridemic pancreatitis-associated lung injury.
RPLP1, an NS4B-interacting protein, enhances production of CSFV through promoting translation of viral genome.
Regulation of host factor γ-H2AX level and location by enterovirus A71 for viral replication.
Tetrandrine alleviates inflammation and neuron apoptosis in experimental traumatic brain injury by regulating the IRE1α/JNK/CHOP signal pathway.
Pathogenic variants in TSC2 might cause premature ovarian insufficiency through activated mTOR induced hyperactivation of primordial follicles.
Di-2-ethylhexyl phthalate-induced miR-155-5p promoted lipid metabolism via inhibiting cAMP/PKA signaling pathway in human trophoblastic HTR-8/Svneo cells.
Epoxymicheliolide prevents dextran sulfate sodium-induced colitis in mice by inhibiting TAK1-NF-κB pathway and activating Keap1-NRF2 signaling in macrophages.
Eplerenone inhibits the macrophage-to-myofibroblast transition in rats with UUO-induced type 4 cardiorenal syndrome through the MR/CTGF pathway.
Nodakenin attenuates cartilage degradation and inflammatory responses in a mice model of knee osteoarthritis by regulating mitochondrial Drp1/ROS/NLRP3 axis.
Blockade of CBX4-mediated β-catenin SUMOylation attenuates airway epithelial barrier dysfunction in asthma.
Brown adipocytes promote epithelial mesenchymal transition of neuroblastoma cells by inducing PPAR-γ/UCP2 expression.
Isorhamnetin protects zearalenone-induced damage via the PI3K/Akt signaling pathway in porcine ovarian granulosa cells.
Systemic gene therapy for methylmalonic acidemia using the novel adeno-associated viral vector 44.9.
Melatonin Maintains Homeostasis and Potentiates the Anti-inflammatory Response in Staphylococcus aureus-Induced Mastitis through microRNA-16b/YAP1.
GABA regulates IL-1β production in macrophages.
CIP2A deficiency promotes depression-like behaviors in mice through inhibition of dendritic arborization.
Silencing of lncRNA SNHG17 inhibits the tumorigenesis of epithelial ovarian cancer through regulation of miR-485-5p/AKT1 axis.
LncRNA GAS5 regulates the Wnt/β-catenin pathway through the miR-18a-5p/AXIN2/GSK3β axis to inhibit the proliferation and migration of bladder cancer cells.
Mechanically activated ion channel Piezo1 contributes to melanoma malignant progression through AKT/mTOR signaling.
Exosome-transmitted S100A4 induces immunosuppression and non-small cell lung cancer development by activating STAT3.
Quercetin ameliorates memory impairment by inhibiting abnormal microglial activation in a mouse model of paradoxical sleep deprivation.
Geraniol-Mediated Suppression of Endoplasmic Reticulum Stress Protects against Cerebral Ischemia-Reperfusion Injury via the PERK-ATF4-CHOP Pathway.
SMYD3 associates with the NuRD (MTA1/2) complex to regulate transcription and promote proliferation and invasiveness in hepatocellular carcinoma cells.
Targeting Cell Membranes, Depleting ROS by Dithiane and Thioketal-Containing Polymers with Pendant Cholesterols Delivering Necrostatin-1 for Glaucoma Treatment.
4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer.
MALAT1 modulates alternative splicing by cooperating with the splicing factors PTBP1 and PSF.
Prognostic and therapeutic implication of m6A methylation in Crohn disease.
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation.
Myo-Inositol Supplementation Alleviates Cisplatin-Induced Acute Kidney Injury via Inhibition of Ferroptosis.
β-hydroxybutyrate inhibits ferroptosis-mediated pancreatic damage in acute liver failure through the increase of H3K9bhb.
The Ginsenoside Compound K Suppresses Stem-Cell-like Properties and Colorectal Cancer Metastasis by Targeting Hypoxia-Driven Nur77-Akt Feed-Forward Signaling.
A multifunctional black phosphorus-based adhesive patch intrinsically induces partial EMT for effective burn wound healing.
LncRNA ELF3-AS1 inhibits gastric cancer by forming a negative feedback loop with SNAI2 and regulates ELF3 mRNA stability via interacting with ILF2/ILF3 complex.
Targeting regulation of VEGF by BPTF in non-small cell lung cancer and its potential clinical significance.
Long noncoding RNA HOTAIR facilitates pulmonary vascular endothelial cell apoptosis via DNMT1 mediated hypermethylation of Bcl-2 promoter in COPD.
Electroacupuncture Alleviates Neuroinflammation by Inhibiting the HMGB1 Signaling Pathway in Rats with Sepsis-Associated Encephalopathy.
Fluid shear stress-induced down-regulation of miR-146a-5p inhibits osteoblast apoptosis via targeting SMAD4.
Inhibition of TIGAR Increases Exogenous p53 and Cisplatin Combination Sensitivity in Lung Cancer Cells by Regulating Glycolytic Flux.
Genome-Wide Analysis of Circular RNAs Reveals circCHRNG Regulates Sheep Myoblast Proliferation via miR-133/SRF and MEF2A Axis.
Polystyrene Microplastics Postpone APAP-Induced Liver Injury through Impeding Macrophage Polarization.
The selective NLRP3 inflammasome inhibitor MCC950 improves isoproterenol-induced cardiac dysfunction by inhibiting cardiomyocyte senescence.
Energy sensor AMPK gamma regulates translation via phosphatase PPP6C independent of AMPK alpha.
PRL stimulates mitotic errors by suppressing kinetochore-localized activation of AMPK during mitosis.
Ferroptosis as a mechanism of oligodendrocyte loss and demyelination in experimental autoimmune encephalomyelitis.
Role of Ero1α in cognitive impairment induced by chronic hypoxia.
Fine-tuning of mTOR signaling by the UBE4B-KLHL22 E3 ubiquitin ligase cascade in brain development.
Coxsackievirus Group B3 Has Oncolytic Activity against Colon Cancer through Gasdermin E-Mediated Pyroptosis.
Matrix protein Tenascin-C promotes kidney fibrosis via STAT3 activation in response to tubular injury.
Fecal Microbiota Transplantation Alleviated Cerebral Ischemia Reperfusion Injury in Obese Rats.
miR21 modulates the Hippo signaling pathway via interference with PP2A Bβ to inhibit trophoblast invasion and cause preeclampsia.
PINK1/Parkin-Mediated Mitophagy Partially Protects against Inorganic Arsenic-Induced Hepatic Macrophage Polarization in Acute Arsenic-Exposed Mice.
Treadmill training mitigates bone deterioration via inhibiting NLRP3/Caspase1/IL-1β signaling in aged rats.
Silibinin Overcomes EMT-Driven Lung Cancer Resistance to New-Generation ALK Inhibitors.
DEXMEDETOMIDINE PREVENTS PDIA3 DECREASE BY ACTIVATING α2-ADRENERGIC RECEPTOR TO ALLEVIATE INTESTINAL I/R IN MICE.
Non-canonical phosphoglycerate dehydrogenase activity promotes liver cancer growth via mitochondrial translation and respiratory metabolism.
COOH-terminal fragment of APP interacts with p62, forms an aggregate, and induces autophagic degradation in Alzheimer's cell model.
Aloe polymeric acemannan inhibits the cytokine storm in mouse pneumonia models by modulating macrophage metabolism.
Alleviating effects of selenium on fluoride-induced testosterone synthesis disorder and reproduction toxicity in rats.
Fucoidan ameliorates LPS-induced neuronal cell damage and cognitive impairment in mice.
Resveratrol activates the SIRT1/PGC-1 pathway in mice to improve synaptic-related cognitive impairment after TBI.
Subchronic Oral Cylindrospermopsin Exposure Alters the Host Gut Microbiome and Is Associated with Progressive Hepatic Inflammation, Stellate Cell Activation, and Mild Fibrosis in a Preclinical Study.
Intestinal epithelial β Klotho is a critical protective factor in alcohol-induced intestinal barrier dysfunction and liver injury.
Suppression of nitric oxide synthase aggravates non-alcoholic steatohepatitis and atherosclerosis in SHRSP5/Dmcr rat via acceleration of abnormal lipid metabolism.
Porphyromonas gingivalis lipopolysaccharide affects the angiogenic function of endothelial progenitor cells via Akt/FoxO1 signaling.
Mesenchymal stem cell-exosome-mediated matrix metalloproteinase 1 participates in oral leukoplakia and carcinogenesis by inducing angiogenesis.
Umbilical cord-derived mesenchymal stem cell conditioned medium reverses neuronal oxidative injury by inhibition of TRPM2 activation and the JNK signaling pathway.
Oxidative stress and Cx43-mediated apoptosis are involved in PFOS-induced nephrotoxicity.
Transcriptional regulator CTR9 promotes hepatocellular carcinoma progression and metastasis via increasing PEG10 transcriptional activity.
Alteration of the neuronal and glial cell profiles in Neu1-deficient zebrafish.
Extracellular HSP90α promotes cellular senescence by modulating TGF-β signaling in pulmonary fibrosis.
Targeted Disruption of a Proximal Tubule-Specific TMEM174 Gene in Mice Causes Hyperphosphatemia and Vascular Calcification.
GRASP55 regulates the unconventional secretion and aggregation of mutant huntingtin.
Nuclear ribonucleoprotein RALY targets virus nucleocapsid protein and induces autophagy to restrict porcine epidemic diarrhea virus replication.
MgIG exerts therapeutic effects on crizotinib-induced hepatotoxicity by limiting ROS-mediated autophagy and pyroptosis.
Human breast milk-derived exosomes through inhibiting AT II cell apoptosis to prevent bronchopulmonary dysplasia in rat lung.
The transcription factor TOX is involved in the regulation of T-cell exhaustion in neuroblastoma.
Cyclometalated iridium(III) dithioformic acid complexes as mitochondria-targeted imaging and anticancer agents.
Anti-inflammatory Properties of the Alpha-Melanocyte-Stimulating Hormone in Models of Granulomatous Inflammation.
Guanxinning tablet inhibits the interaction between leukocyte integrin Mac-1 and platelet GPIbα for antithrombosis without increased bleeding risk.
DDIT3/CHOP mediates the inhibitory effect of ER stress on chondrocyte differentiation by AMPKα-SIRT1 pathway.
Cullin-associated and neddylation-dissociated 1 protein (CAND1) governs cardiac hypertrophy and heart failure partially through regulating calcineurin degradation.
Leonurine alleviates ferroptosis in cisplatin-induced acute kidney injury by activating the Nrf2 signalling pathway.
NSUN2-mediated RNA m(5)C modification modulates uveal melanoma cell proliferation and migration.
Neuropeptide Y promotes hepatic apolipoprotein A1 synthesis and secretion through neuropeptide Y Y5 receptor.
Modification of taxifolin particles with an enteric coating material promotes repair of acute liver injury in mice through modulation of inflammation and autophagy signaling pathway.
TPN171H alleviates pulmonary hypertension via inhibiting inflammation in hypoxia and monocrotaline-induced rats.
Microbial and metabolic profiles of bronchopulmonary dysplasia and therapeutic effects of potential probiotics Limosilactobacillus reuteri and Bifidobacterium bifidum.
Bacillus subtilis WB800N alleviates diabetic wounds in mice by regulating gut microbiota homeostasis and TLR2.
Neomycin inhibits Megalocytivirus infection in fish by antagonizing the increase of intracellular reduced glutathione.
LncRNA SNHG11 promotes the malignant transformation of human bronchial epithelial cells induced by beryllium sulfate.
High-fructose corn syrup promotes proinflammatory Macrophage activation via ROS-mediated NF-κB signaling and exacerbates colitis in mice.
Paeoniflorin ameliorates diabetic liver injury by targeting the TXNIP-mediated NLRP3 inflammasome in db/db mice.
Burdock (Arctium lappa L.) leaf flavonoids rich in morin and quercetin 3-O-rhamnoside ameliorate lipopolysaccharide-induced inflammation and oxidative stress in RAW264.7 cells.
High-affinity SOAT1 ligands remodeled cholesterol metabolism program to inhibit tumor growth.
The inhibitory effect and mechanism of Yi-qi-hua-yu-jie-du decoction on the drug resistance of gastric cancer stem cells based on ABC transporters.
Pharmacological induction of AMFR increases functional EAAT2 oligomer levels and reduces epileptic seizures in mice.
Construction of Attenuated Strains for Red-Spotted Grouper Nervous Necrosis Virus (RGNNV) via Reverse Genetic System.
The mechanism of the imbalance between proliferation and ferroptosis in pulmonary artery smooth muscle cells based on the activation of SLC7A11.
Retinal Src homology region 2-containing protein tyrosine phosphatase 2 silencing alleviates diabetic retinopathy via suppressing inflammatory response and oxidative stress by regulating Yes-associated protein 1 activity.
Incomplete autophagy promotes the proliferation of Mycoplasma hyopneumoniae through the JNK and Akt pathways in porcine alveolar macrophages.
6-Hydroxydopamine-Induced Neurotoxicity in Rat Model of Parkinson's Disease: Is Reversed via Anti-Oxidative Activities of Curcumin and Aerobic Exercise Therapy.
Kaempferol-Driven Inhibition of Listeriolysin O Pore Formation and Inflammation Suppresses Listeria monocytogenes Infection.
GNIP1 functions both as a scaffold protein and an E3 ubiquitin ligase to regulate autophagy in lung cancer.
LncRNA H19 inhibits ER stress induced apoptosis and improves diabetic cardiomyopathy by regulating PI3K/AKT/mTOR axis.
Dual antioxidant activity and the related mechanisms of a novel pentapeptide GLP4 from the fermented mycelia of Ganoderma lingzhi.
Circ_0047339 promotes the activation of fibroblasts and affects the development of urethral stricture by targeting the miR-4691-5p/TSP-1 axis.
Downregulation of IL-8 and IL-10 by the Activation of Ca(2+)-Activated K(+) Channel K(Ca)3.1 in THP-1-Derived M(2) Macrophages.
Effects of MICU1-Mediated Mitochondrial Calcium Uptake on Energy Metabolism and Quality of Vitrified-Thawed Mouse Metaphase II Oocytes.
Cornuside Is a Potential Agent against Alzheimer's Disease via Orchestration of Reactive Astrocytes.
Staphylococcus aureus-Induced Necroptosis Promotes Mitochondrial Damage in Goat Endometrial Epithelial Cells.
The mechanism of Yinchenhao decoction in treating obstructive-jaundice-induced liver injury based on Nrf2 signaling pathway.
Rhodococcus equi-Derived Extracellular Vesicles Promoting Inflammatory Response in Macrophage through TLR2-NF-κB/MAPK Pathways.
Mesenchymal stem cells-derived exosomes prevent sepsis-induced myocardial injury by a CircRTN4/miR-497-5p/MG53 pathway.
ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection.
BRAT1 links Integrator and defective RNA processing with neurodegeneration.
Breaking the Iron Homeostasis: A "Trojan Horse" Self-Assembled Nanodrug Sensitizes Homologous Recombination Proficient Ovarian Cancer Cells to PARP Inhibition.
Neu1 deficiency increases the susceptibility of zebrafish to Edwardsiella piscicida infection via lysosomal dysfunction.
Diallyl trisulfide sensitizes radiation therapy on glioblastoma through directly targeting thioredoxin 1.
GPT2 Is Induced by Hypoxia-Inducible Factor (HIF)-2 and Promotes Glioblastoma Growth.
Quantitative Acetylomics Uncover Acetylation-Mediated Pathway Changes Following Histone Deacetylase Inhibition in Anaplastic Large Cell Lymphoma.
Single-cell atlas of diverse immune populations in the advanced biliary tract cancer microenvironment.
Developmental differences of in vitro cultured murine bone marrow- and fetal liver-derived megakaryocytes.
A Novel Pectin-Like Glycopeptide Isolated from the Fruit of Fructus Mori Impedes Aggregation and Production of Aβ(42).
YTHDC1 is downregulated by the YY1/HDAC2 complex and controls the sensitivity of ccRCC to sunitinib by targeting the ANXA1-MAPK pathway.
Phenolic Acids from Fructus Chebulae Immaturus Alleviate Intestinal Ischemia-Reperfusion Injury in Mice through the PPARα/NF-κB Pathway.
Construction of a novel model based on cell-in-cell-related genes and validation of KRT7 as a biomarker for predicting survival and immune microenvironment in pancreatic cancer.
CD38 Mediates Lung Fibrosis by Promoting Alveolar Epithelial Cell Aging.
Quantitative Proteomics Explore the Potential Targets and Action Mechanisms of Hydroxychloroquine.
Inert Pepper aptamer-mediated endogenous mRNA recognition and imaging in living cells.
Melatonin ameliorates diabetic hyperglycaemia-induced impairment of Leydig cell steroidogenic function through activation of SIRT1 pathway.
The NS4A Protein of Classical Swine Fever Virus Suppresses RNA Silencing in Mammalian Cells.
Hsp70 Inhibits the Replication of Fowl Adenovirus Serotype 4 by Suppressing Viral Hexon with the Assistance of DnaJC7.
The effects of Jiawei Duhuo Jisheng mixture on Wnt/β-catenin signaling pathway in the synovium inflamed by knee osteoarthritis: An in vitro and in vivo experiment.
Jianpi Huayu decoction inhibits the epithelial-mesenchymal transition of hepatocellular carcinoma cells by suppressing exosomal miR-23a-3p/Smad signaling.
MAB21L1 promotes survival of lens epithelial cells through control of αB-crystallin and ATR/CHK1/p53 pathway.
MDM2-mediated ubiquitination of LKB1 contributes to the development of diabetic cataract.
Multifunctional chitin-based hollow nerve conduit for peripheral nerve regeneration and neuroma inhibition.
4-Octyl itaconate suppresses the osteogenic response in aortic valvular interstitial cells via the Nrf2 pathway and alleviates aortic stenosis in mice with direct wire injury.
The Annexin A2-Notch regulatory loop in hepatocytes promotes liver fibrosis in NAFLD by increasing osteopontin expression.
Tangeretin suppresses osteoarthritis progression via the Nrf2/NF-κB and MAPK/NF-κB signaling pathways.
EML4-ALK G1202R mutation induces EMT and confers resistance to ceritinib in NSCLC cells via activation of STAT3/Slug signaling.
c-Myc participates in high glucose-mediated endothelial inflammation via upregulation of IRAK1 expression in diabetic nephropathy.
LPS induces pulmonary microvascular endothelial cell barrier dysfunction by upregulating ceramide production.
Decreased efficacy of the ketamine and scopolamine-induced sustained antidepressant-like effects in rats receiving metformin.
COP1 Acts as a Ubiquitin Ligase for PCDH9 Ubiquitination and Degradation in Human Glioma.
Interleukin-17A Contributed to the Damage of Blood-CNS Barriers During Streptococcus suis Meningitis.
A comparison expression analysis of CXCR4, CXCL9 and Caspase-9 in dermal vascular endothelial cells between keloids and normal skin on chemotaxis and apoptosis.
Grem1 accelerates nucleus pulposus cell apoptosis and intervertebral disc degeneration by inhibiting TGF-β-mediated Smad2/3 phosphorylation.
Enterobacter cloacae: a villain in CaOx stone disease?
Linagliptin ameliorates pulmonary fibrosis in systemic sclerosis mouse model via inhibition of endothelial-to-mesenchymal transition.
Functional characterization of human organic anion transporter 10 (OAT10/SLC22A13) as an orotate transporter.
Early Aerobic Exercise Promotes Neurological Function Recovery of Rats after Cerebral Ischemia/Reperfusion by Upregulating the Expression of Heat Shock Protein A5.
MicroRNA-22 represses glioma development via activation of macrophage-mediated innate and adaptive immune responses.
Interleukin-17A mediates tobacco smoke-induced lung cancer epithelial-mesenchymal transition through transcriptional regulation of ΔNp63α on miR-19.
MiR-125b enhances doxorubicin-induced cardiotoxicity by suppressing the nucleus-cytoplasmic translocation of YAP via targeting STARD13.
UHRF1 shapes both the trophoblast invasion and decidual macrophage differentiation in early pregnancy.
TIMP2 mediates endoplasmic reticulum stress contributing to sepsis-induced acute kidney injury.
The alleviative effect of flavonol-type Nrf2 activator rhamnazin from Physalis alkekengi L. var. franchetii (Mast.) Makino on pulmonary disorders.
FAK regulates cardiomyocyte mitochondrial fission and function through Drp1.
Occludin facilitates tumour angiogenesis in bladder cancer by regulating IL8/STAT3 through STAT4.
Genetic instability of lung induced by carbon black nanoparticles is related with Plk1 signals changes.
Molecular mechanism of the TGF‑β/Smad7 signaling pathway in ulcerative colitis.
Exosomes derived from the blood of patients with sepsis regulate apoptosis and aerobic glycolysis in human myocardial cells via the hsa‑miR‑1262/SLC2A1 signaling pathway.
USP5 promotes breast cancer cell proliferation and metastasis by stabilizing HIF2α.
UBE2T is upregulated, predicts poor prognosis, and promotes cell proliferation and invasion by promoting epithelial-mesenchymal transition via inhibiting autophagy in an AKT/mTOR dependent manner in ovarian cancer.
Itaconate attenuates osteoarthritis by inhibiting STING/NF-κB axis in chondrocytes and promoting M2 polarization in macrophages.
Pharmacological targeting macrophage phenotype via gut-kidney axis ameliorates renal fibrosis in mice.
Tetrastigma hemsleyanum Diels et Gilg ameliorates lipopolysaccharide induced sepsis via repairing the intestinal mucosal barrier.
circHIPK3 regulates cell proliferation and migration by sponging microRNA-124 and regulating serine/threonine kinase 3 expression in esophageal squamous cell carcinoma.
Human umbilical vein endothelial cells-derived exosomes enhance cardiac function after acute myocardial infarction by activating the PI3K/AKT signaling pathway.
HSP90 promotes radioresistance of cervical cancer cells via reducing FBXO6-mediated CD147 polyubiquitination.
The OPG/RANKL/RANK system modulates calcification of common carotid artery in simulated microgravity rats by regulating NF-κB pathway.
BRD4 promotes the migration and invasion of bladder cancer cells through the Sonic hedgehog signaling pathway and enhances cisplatin resistance.
LATS1 is a central signal transmitter for achieving full type-I interferon activity.
Mechanosensitive Piezo1 channels mediate renal fibrosis.
Sp1 S-Sulfhydration Induced by Hydrogen Sulfide Inhibits Inflammation via HDAC6/MyD88/NF-κB Signaling Pathway in Adjuvant-Induced Arthritis.
Stearic Acid Activates the PI3K-mTOR-4EBP1/S6K and mTOR-SREBP-1 Signaling Axes through FATP4-CDK1 To Promote Milk Synthesis in Primary Bovine Mammary Epithelial Cells.
The Slack Channel Regulates Anxiety-Like Behaviors via Basolateral Amygdala Glutamatergic Projections to Ventral Hippocampus.
METTL3-mediated m(6)A modification of TIMP2 mRNA promotes podocyte injury in diabetic nephropathy.
TNFAIP8 protein functions as a tumor suppressor in inflammation-associated colorectal tumorigenesis.
Pdcd4 promotes lipid deposition by attenuating PPARα-mediated fatty acid oxidation in hepatocytes.
Positive feedback regulation of microglial glucose metabolism by histone H4 lysine 12 lactylation in Alzheimer's disease.
miR-AB, a miRNA-based shRNA viral toolkit for multicolor-barcoded multiplex RNAi at a single-cell level.
Vitamin K2 Modulates Mitochondrial Dysfunction Induced by 6-Hydroxydopamine in SH-SY5Y Cells via Mitochondrial Quality-Control Loop.
Proteomic Analysis of Vero Cells Infected with Pseudorabies Virus.
Ginsenoside Rk1 regulates glutamine metabolism in hepatocellular carcinoma through inhibition of the ERK/c-Myc pathway.
Antioxidant Activity of Acanthopanax senticosus Flavonoids in H(2)O(2)-Induced RAW 264.7 Cells and DSS-Induced Colitis in Mice.
LMOD1, an oncogene associated with Lauren classification, regulates the metastasis of gastric cancer cells through the FAK-AKT/mTOR pathway.
Cdh1 Deficiency Sensitizes TNBC Cells to PARP Inhibitors.
Neuron-specific enolase promotes stem cell-like characteristics of small-cell lung cancer by downregulating NBL1 and activating the BMP2/Smad/ID1 pathway.
Trappc9 Deficiency Impairs the Plasticity of Stem Cells.
MicroRNA-146a-5p-modified human umbilical cord mesenchymal stem cells enhance protection against diabetic nephropathy in rats through facilitating M2 macrophage polarization.
Mandarin Fish (Siniperca chuatsi) p53 Regulates Glutaminolysis Induced by Virus via the p53/miR145-5p/c-Myc Pathway in Chinese Perch Brain Cells.
Propofol protects against high glucose-mediated endothelial injury via inhibition of COX2 and iNOS expressions.
RETREG1-mediated ER-phagy activation induced by glucose deprivation alleviates nucleus pulposus cell damage via ER stress pathway.
A methylprednisolone-loaded and core-shell nanofiber-covered stent-graft to prevent inflammation and reduce degradation in aortic dissection.
Network pharmacology analysis and experimental validation to explore the mechanism of Shenlian extract on myocardial ischemia.
Reversal of Lipid Metabolism Dysregulation by Selenium and Folic Acid Co-Supplementation to Mitigate Pathology in Alzheimer's Disease.
A novel oncogenic seRNA promotes nasopharyngeal carcinoma metastasis.
Telomerase RNA TERC and the PI3K-AKT pathway form a positive feedback loop to regulate cell proliferation independent of telomerase activity.
ORP5 promotes tumor metastasis via stabilizing c-Met in renal cell carcinoma.
Comparative Proteomic Analysis Reveals Mx1 Inhibits Senecavirus A Replication in PK-15 Cells by Interacting with the Capsid Proteins VP1, VP2 and VP3.
HGF/c-Met pathway facilitates the perineural invasion of pancreatic cancer by activating the mTOR/NGF axis.
Oryzanol alleviates high fat and cholesterol diet-induced hypercholesterolemia associated with the modulation of the gut microbiota in hamsters.
Age-dependent effects of a high-fat diet combined with dietary advanced glycation end products on cognitive function and protection with voluntary exercise.
Exosomal miR-146a-5p and miR-155-5p promote CXCL12/CXCR7-induced metastasis of colorectal cancer by crosstalk with cancer-associated fibroblasts.
Suppression of premature transcription termination leads to reduced mRNA isoform diversity and neurodegeneration.
TRIM26-mediated degradation of nucleocapsid protein limits porcine reproductive and respiratory syndrome virus-2 infection.
Graphene quantum dots rescue angiogenic retinopathy via blocking STAT3/Periostin/ERK signaling.
Flubendazole induces mitochondrial dysfunction and DRP1-mediated mitophagy by targeting EVA1A in breast cancer.
Cavβ1 regulates T cell expansion and apoptosis independently of voltage-gated Ca(2+) channel function.
Inhibition of KIF23 Alleviates IPAH by Targeting Pyroptosis and Proliferation of PASMCs.
Regulatory variants at 2q33.1 confer schizophrenia risk by modulating distal gene TYW5 expression.
β-catenin correlates with the progression of colon cancers and berberine inhibits the proliferation of colon cancer cells by regulating the β-catenin signaling pathway.
Identified human breast milk compositions effectively inhibit SARS-CoV-2 and variants infection and replication.
VPS28 regulates brain vasculature by controlling neuronal VEGF trafficking through extracellular vesicle secretion.
Xihuang pills induce apoptosis in hepatocellular carcinoma by suppressing phosphoinositide 3-kinase/protein kinase-B/mechanistic target of rapamycin pathway.
EGFR/MET promotes hepatocellular carcinoma metastasis by stabilizing tumor cells and resisting to RTKs inhibitors in circulating tumor microemboli.
Tumor-resident intracellular microbiota promotes metastatic colonization in breast cancer.
miR-199-5p regulates spermiogenesis at the posttranscriptional level via targeting Tekt1 in allotriploid crucian carp.
Intestinal Tuft-2 cells exert antimicrobial immunity via sensing bacterial metabolite N-undecanoylglycine.
An oxygen-adaptive interaction between SNHG12 and occludin maintains blood-brain barrier integrity.
Dapagliflozin, sildenafil and their combination in monocrotaline-induced pulmonary arterial hypertension.
Proteomic Studies of the Mechanism of Cytotoxicity, Induced by Palytoxin on HaCaT Cells.
Chidamide and mitomycin C exert synergistic cytotoxic effects against bladder cancer cells in vitro and suppress tumor growth in a rat bladder cancer model.
Microcystin-leucine arginine (MC-LR) induces mouse ovarian inflammation by promoting granulosa cells to produce inflammatory cytokine via activation of cGAS-STING signaling.
Norcantharidin Induces Immunogenic Cell Death of Bladder Cancer Cells through Promoting Autophagy in Acidic Culture.
Urolithin A promotes mitophagy and suppresses NLRP3 inflammasome activation in lipopolysaccharide-induced BV2 microglial cells and MPTP-induced Parkinson's disease model.
Golgi Phosphoprotein 3 Confers Radioresistance via Stabilizing EGFR in Lung Adenocarcinoma.
Inhibiting Hyper-O-GlcNAcylation of c-Myc accelerate diabetic wound healing by alleviating keratinocyte dysfunction.
Comprehensive analysis of abnormal expression, prognostic value and oncogenic role of the hub gene FN1 in pancreatic ductal adenocarcinoma via bioinformatic analysis and in vitro experiments.
Identification of KIF4A as a pan-cancer diagnostic and prognostic biomarker via bioinformatics analysis and validation in osteosarcoma cell lines.
Integrated Analysis of Ferroptosis-Related Biomarker Signatures to Improve the Diagnosis and Prognosis Prediction of Ovarian Cancer.
Identification and Validation of HOTAIRM1 as a Novel Biomarker for Oral Squamous Cell Carcinoma.
Differential Expression Profiles and Potential Intergenerational Functions of tRNA-Derived Small RNAs in Mice After Cadmium Exposure.
Exosomal MIF Derived From Nasopharyngeal Carcinoma Promotes Metastasis by Repressing Ferroptosis of Macrophages.
PPy@Fe(3)O(4) Nanoparticles Inhibit Tumor Growth and Metastasis Through Chemodynamic and Photothermal Therapy in Non-small Cell Lung Cancer.
Keratin 17 Is Required for Lipid Metabolism in Keratinocytes and Benefits Epidermal Permeability Barrier Homeostasis.
Cadherin-12 Regulates Neurite Outgrowth Through the PKA/Rac1/Cdc42 Pathway in Cortical Neurons.
Multiple DSB Resection Activities Redundantly Promote Alternative End Joining-Mediated Class Switch Recombination.
TGR5 Activation Ameliorates Mitochondrial Homeostasis via Regulating the PKCδ/Drp1-HK2 Signaling in Diabetic Retinopathy.
LncRNA FEZF1-AS1 Promotes Multi-Drug Resistance of Gastric Cancer Cells via Upregulating ATG5.
Eicosapentaenoic Acid-Induced Autophagy Attenuates Intervertebral Disc Degeneration by Suppressing Endoplasmic Reticulum Stress, Extracellular Matrix Degradation, and Apoptosis.
Autophagy Regulates VDAC3 Ubiquitination by FBXW7 to Promote Erastin-Induced Ferroptosis in Acute Lymphoblastic Leukemia.
TMT-Based Proteomic Explores the Influence of DHEA on the Osteogenic Differentiation of hBMSCs.
Lack of MOF Decreases Susceptibility to Hypoxia and Promotes Multidrug Resistance in Hepatocellular Carcinoma via HIF-1α.
ESRRB Facilitates the Conversion of Trophoblast-Like Stem Cells From Induced Pluripotent Stem Cells by Directly Regulating CDX2.
Role of GRK2 in Trophoblast Necroptosis and Spiral Artery Remodeling: Implications for Preeclampsia Pathogenesis.
Cardioprotective Role of SIRT5 in Response to Acute Ischemia Through a Novel Liver-Cardiac Crosstalk Mechanism.
Cyclophosphamide Exposure Causes Long-Term Detrimental Effect of Oocytes Developmental Competence Through Affecting the Epigenetic Modification and Maternal Factors' Transcription During Oocyte Growth.
The E3 Ligase PIAS1 Regulates p53 Sumoylation to Control Stress-Induced Apoptosis of Lens Epithelial Cells Through the Proapoptotic Regulator Bax.
SARS-CoV-2 Host Receptor ACE2 Protein Expression Atlas in Human Gastrointestinal Tract.
MYC Enhances Cholesterol Biosynthesis and Supports Cell Proliferation Through SQLE.
NTNG1 Modulates Cisplatin Resistance in Epithelial Ovarian Cancer Cells via the GAS6/AXL/Akt Pathway.
TAp63α Is Involved in Tobacco Smoke-Induced Lung Cancer EMT and the Anti-cancer Activity of Curcumin via miR-19 Transcriptional Suppression.
Grb2 Induces Cardiorenal Syndrome Type 3: Roles of IL-6, Cardiomyocyte Bioenergetics, and Akt/mTOR Pathway.
Deficiency of Sirtuin 1 Impedes Endometrial Decidualization in Recurrent Implantation Failure Patients.
The Cancer-Testis Long Non-coding RNA PCAT6 Facilitates the Malignant Phenotype of Ovarian Cancer by Sponging miR-143-3p.
Zirconia Nanoparticles Induce HeLa Cell Death Through Mitochondrial Apoptosis and Autophagy Pathways Mediated by ROS.
Inhibition of miR-96-5p May Reduce Aβ42/Aβ40 Ratio via Regulating ATP-binding cassette transporter A1.
Honokiol Restores Microglial Phagocytosis by Reversing Metabolic Reprogramming.
JMJD1A/NR4A1 Signaling Regulates the Procession of Renal Tubular Epithelial Interstitial Fibrosis Induced by AGEs in HK-2.
A Global Phosphorylation Atlas of Proteins Within Pathological Site of Rotator Cuff Tendinopathy.
Lanthanum Chloride Sensitizes Cisplatin Resistance of Ovarian Cancer Cells via PI3K/Akt Pathway.
Auranofin and ICG-001 Emerge Synergistic Anti-tumor Effect on Canine Breast Cancer by Inducing Apoptosis via Mitochondrial Pathway.
Maslinic Acid Attenuates Ischemia/Reperfusion Injury-Induced Myocardial Inflammation and Apoptosis by Regulating HMGB1-TLR4 Axis.
Spermidine Affects Cardiac Function in Heart Failure Mice by Influencing the Gut Microbiota and Cardiac Galectin-3.
Loss of Hepatic Surf4 Depletes Lipid Droplets in the Adrenal Cortex but Does Not Impair Adrenal Hormone Production.
S-Propargyl-Cysteine Attenuates Diabetic Cardiomyopathy in db/db Mice Through Activation of Cardiac Insulin Receptor Signaling.
The Regulation of Staphylococcus aureus-Induced Inflammatory Responses in Bovine Mammary Epithelial Cells.
β-Sitosterol Ameliorates Endometrium Receptivity in PCOS-Like Mice: The Mediation of Gut Microbiota.
Exosomal MicroRNA-181a Derived From Mesenchymal Stem Cells Improves Gut Microbiota Composition, Barrier Function, and Inflammatory Status in an Experimental Colitis Model.
Liraglutide Protects Nucleus Pulposus Cells Against High-Glucose Induced Apoptosis by Activating PI3K/Akt/ mTOR/Caspase-3 and PI3K/Akt/GSK3β/Caspase-3 Signaling Pathways.
Identification of the Prognostic Value Among Suppressor Of Cytokine Signaling Family Members in Kidney Renal Clear Cell Carcinoma.
Hydroxysafflor yellow A acutely attenuates blood-brain barrier permeability, oxidative stress, inflammation and apoptosis in traumatic brain injury in rats1.
Autophagy Prevents Osteocyte Cell Death under Hypoxic Conditions.
Long Noncoding RNA HCG9 Promotes Osteosarcoma Progression through RAD51 by Acting as a ceRNA of miR-34b-3p.
Exosomes Containing LINC00636 Inhibit MAPK1 through the miR-450a-2-3p Overexpression in Human Pericardial Fluid and Improve Cardiac Fibrosis in Patients with Atrial Fibrillation.
TRIM29 Reverses Oxaliplatin Resistance of P53 Mutant Colon Cancer Cell.
Constitutive Androstane Receptor-Mediated Inhibition of Metformin on Phase II Metabolic Enzyme SULT2A1.
Ze-Qi-Tang Formula Induces Granulocytic Myeloid-Derived Suppressor Cell Apoptosis via STAT3/S100A9/Bcl-2/Caspase-3 Signaling to Prolong the Survival of Mice with Orthotopic Lung Cancer.
ADAM17 Mediates Hypoxia-Induced Keratinocyte Migration via the p38/MAPK Pathway.
Tanshinone I Mitigates Steroid-Induced Osteonecrosis of the Femoral Head and Activates the Nrf2 Signaling Pathway in Rats.
Catalpol-Induced AMPK Activation Alleviates Cisplatin-Induced Nephrotoxicity through the Mitochondrial-Dependent Pathway without Compromising Its Anticancer Properties.
In Hepatocellular Carcinoma, miRNA-296-3p Targets MSL2 and Suppresses Cell Proliferation and Invasion.
UBC Mediated by SEPT6 Inhibited the Progression of Prostate Cancer.
High Methionine Diet-Induced Alzheimer's Disease like Symptoms Are Accompanied by 5-Methylcytosine Elevated Levels in the Brain.
Neferine Protects against Hypoxic-Ischemic Brain Damage in Neonatal Rats by Suppressing NLRP3-Mediated Inflammasome Activation.
The Regulation of ROS- and BECN1-Mediated Autophagy by Human Telomerase Reverse Transcriptase in Glioblastoma.
Overexpression of RIPK4 Predicts Poor Prognosis and Promotes Metastasis in Ovarian Cancer.
Uncovering the Pharmacology of Xiaochaihu Decoction in the Treatment of Acute Pancreatitis Based on the Network Pharmacology.
Taohong Siwu-Containing Serum Enhances Angiogenesis in Rat Aortic Endothelial Cells by Regulating the VHL/HIF-1α/VEGF Signaling Pathway.
GDF-15 Suppresses Atherosclerosis by Inhibiting oxLDL-Induced Lipid Accumulation and Inflammation in Macrophages.
Deficiency of MIF Accentuates Overloaded Compression-Induced Nucleus Pulposus Cell Oxidative Damage via Depressing Mitophagy.
Epigallocatechin-3-Gallate Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease via Inhibition of Apoptosis and Promotion of Autophagy through the ROS/MAPK Signaling Pathway.
EZH2 Mediates miR-146a-5p/HIF-1α to Alleviate Inflammation and Glycolysis after Acute Spinal Cord Injury.
A Network Pharmacology Approach for Exploring the Mechanisms of Panax notoginseng Saponins in Ischaemic Stroke.
Inhibition of α-Synuclein Accumulation Improves Neuronal Apoptosis and Delayed Postoperative Cognitive Recovery in Aged Mice.
POU2F1 Promotes Cell Viability and Tumor Growth in Gastric Cancer through Transcriptional Activation of lncRNA TTC3-AS1.
Baihe Jizihuang Tang Ameliorates Chronic Unpredictable Mild Stress-Induced Depression-Like Behavior: Integrating Network Pharmacology and Brain-Gut Axis Evaluation.
NOX4-Derived ROS Mediates TGF-β1-Induced Metabolic Reprogramming during Epithelial-Mesenchymal Transition through the PI3K/AKT/HIF-1α Pathway in Glioblastoma.
Study on the Antitumor Effect and Glycolysis of Andrographolide in Anaplastic Thyroid Carcinoma.
Berbamine Inhibits Cell Proliferation and Migration and Induces Cell Death of Lung Cancer Cells via Regulating c-Maf, PI3K/Akt, and MDM2-P53 Pathways.
The Key Ingredient Acacetin in Weishu Decoction Alleviates Gastrointestinal Motility Disorder Based on Network Pharmacology Analysis.
The Effect of miR-520b on Macrophage Polarization and T Cell Immunity by Targeting PTEN in Breast Cancer.
OM-MSCs Alleviate the Golgi Apparatus Stress Response following Cerebral Ischemia/Reperfusion Injury via the PEDF-PI3K/Akt/mTOR Signaling Pathway.
The Dietary Supplement γ-Oryzanol Attenuates Hepatic Ischemia Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress and HMGB1/NLRP3 Inflammasome.
Ameliorative Effects and Mechanism of Buyang Huanwu Decoction on Pulmonary Vascular Remodeling: Network and Experimental Analyses.
Comparative Efficacy of Haizao Yuhu Decoction Composed of Different Varieties of Glycyrrhiza in Goiter Rats.
Zinc Regulates Glucose Metabolism of the Spinal Cord and Neurons and Promotes Functional Recovery after Spinal Cord Injury through the AMPK Signaling Pathway.
ARHGAP11A Promotes the Malignant Progression of Gastric Cancer by Regulating the Stability of Actin Filaments through TPM1.
Nrf2 Pathway Ameliorates Bladder Dysfunction in Cyclophosphamide-Induced Cystitis via Suppression of Oxidative Stress.
FAM134B-Mediated ER-phagy Upregulation Attenuates AGEs-Induced Apoptosis and Senescence in Human Nucleus Pulposus Cells.
Chlorogenic Acid Alleviates Colon Mucosal Damage Induced by a High-Fat Diet via Gut Microflora Adjustment to Increase Short-Chain Fatty Acid Accumulation in Rats.
Electroacupuncture Ameliorates Depression-Like Behaviour in Rats by Enhancing Synaptic Plasticity via the GluN2B/CaMKII/CREB Signalling Pathway.
Inhibition of the PERK/TXNIP/NLRP3 Axis by Baicalin Reduces NLRP3 Inflammasome-Mediated Pyroptosis in Macrophages Infected with Mycobacterium tuberculosis.
Microglia-Derived Exosomes Improve Spinal Cord Functional Recovery after Injury via Inhibiting Oxidative Stress and Promoting the Survival and Function of Endothelia Cells.
Inhibiting PP2Acα Promotes the Malignant Phenotype of Gastric Cancer Cells through the ATM/METTL3 Axis.
Qingda granule exerts neuroprotective effects against ischemia/reperfusion-induced cerebral injury via lncRNA GAS5/miR-137 signaling pathway.
NSE, positively regulated by LINC00657-miR-93-5p axis, promotes small cell lung cancer (SCLC) invasion and epithelial-mesenchymal transition (EMT) process.
Simultaneous silencing Aurora-A and UHRF1 inhibits colorectal cancer cell growth through regulating expression of DNMT1 and STAT1.
GABAB receptor inhibits tumor progression and epithelial-mesenchymal transition via the regulation of Hippo/YAP1 pathway in colorectal cancer.
Macrophage migration inhibitory factor regulates joint capsule fibrosis by promoting TGF-β1 production in fibroblasts.
Aurka deficiency in the intestinal epithelium promotes age-induced obesity via propionate-mediated AKT activation.
Targeting HLA-F suppresses the proliferation of glioma cells via a reduction in hexokinase 2-dependent glycolysis.
FOXM1-induced miR-552 expression contributes to pancreatic cancer progression by targeting multiple tumor suppressor genes.
AKR1B10 confers resistance to radiotherapy via FFA/TLR4/NF-κB axis in nasopharyngeal carcinoma.
SOCS2 Suppresses Inflammation and Apoptosis during NASH Progression through Limiting NF-κB Activation in Macrophages.
KMT5A downregulation participated in High Glucose-mediated EndMT via Upregulation of ENO1 Expression in Diabetic Nephropathy.
The imbalance of PGD2-DPs pathway is involved in the type 2 diabetes brain injury by regulating autophagy.
Discovery of a novel HDACi structure that inhibits the proliferation of ovarian cancer cells in vivo and in vitro.
Deubiquitinase PSMD7 promotes the proliferation, invasion, and cisplatin resistance of gastric cancer cells by stabilizing RAD23B.
NCTD Prevents Renal Interstitial Fibrosis via Targeting Sp1/lncRNA Gm26669 Axis.
H2O2 gel bleaching induces cytotoxicity and pain conduction in dental pulp stem cells via intracellular reactive oxygen species on enamel/dentin disc.
Chirality and asymmetry increase the potency of candidate ADRM1/RPN13 inhibitors.
Harmine inhibits breast cancer cell migration and invasion by inducing the degradation of Twist1.
HIV-1 Vpr protein upregulates microRNA-210-5p expression to induce G2 arrest by targeting TGIF2.
Inhibition of histone deacetylation with vorinostat does not prevent tunicamycin-mediated acute kidney injury.
Systematic identification of autophagy-related proteins in Aedes albopictus.
Accurately Controlled Delivery of Temozolomide by Biocompatible UiO-66-NH(2) Through Ultrasound to Enhance the Antitumor Efficacy and Attenuate the Toxicity for Treatment of Malignant Glioma.
Hypermethylation of the Nrf2 Promoter Induces Ferroptosis by Inhibiting the Nrf2-GPX4 Axis in COPD.
Total Flavonoids of Chuju Decrease Oxidative Stress and Cell Apoptosis in Ischemic Stroke Rats: Network and Experimental Analyses.
Photobiomodulation Promotes Repair Following Spinal Cord Injury by Regulating the Transformation of A1/A2 Reactive Astrocytes.
5-HT(7) Receptor Is Involved in Electroacupuncture Inhibition of Chronic Pain in the Spinal Cord.
IL-17 Inhibits Oligodendrocyte Progenitor Cell Proliferation and Differentiation by Increasing K(+) Channel Kv1.3.
Injection of Anti-proBDNF Attenuates Hippocampal-Dependent Learning and Memory Dysfunction in Mice With Sepsis-Associated Encephalopathy.
Tetramethylpyrazine Alleviates Behavioral and Psychological Symptoms of Dementia Through Facilitating Hippocampal Synaptic Plasticity in Rats With Chronic Cerebral Hypoperfusion.
Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice.
IRE1α-XBP1 Affects the Mitochondrial Function of Aβ25-35-Treated SH-SY5Y Cells by Regulating Mitochondria-Associated Endoplasmic Reticulum Membranes.
Oroxin B Attenuates Ovariectomy-Induced Bone Loss by Suppressing Osteoclast Formation and Activity.
Doxazosin Attenuates Liver Fibrosis by Inhibiting Autophagy in Hepatic Stellate Cells via Activation of the PI3K/Akt/mTOR Signaling Pathway.
Baicalin Alleviates Oxidative Stress and Inflammation in Diabetic Nephropathy via Nrf2 and MAPK Signaling Pathway.
Selective Inhibition of 11β-Hydroxysteroid Dehydrogenase Type 1 Attenuates High-Fat Diet-Induced Hepatic Steatosis in Mice.
ADAM17 and NF-κB p65 form a positive feedback loop that facilitates human esophageal squamous cell carcinoma cell viability.
Significance of TEAD Family in Diagnosis, Prognosis and Immune Response for Ovarian Serous Carcinoma.
Ginsenoside Rg1 Inhibits Microglia Pyroptosis Induced by Lipopolysaccharide Through Regulating STAT3 Signaling.
Gαi1 Promoted Proliferation, Migration and Invasion via Activating the Akt-mTOR/Erk-MAPK Signaling Pathway in Renal Cell Carcinoma.
Regulation of IFN-Is by MEF2D Promotes Inflammatory Homeostasis in Microglia.
GADD45B Facilitates Metastasis of Ovarian Cancer Through Epithelial-Mesenchymal Transition.
Upregulation of Neuronal Cylindromatosis Expression is Essential for Electroacupuncture-Mediated Alleviation of Neuroinflammatory Injury by Regulating Microglial Polarization in Rats Subjected to Focal Cerebral Ischemia/Reperfusion.
Orexin-A Attenuates Inflammatory Responses in Lipopolysaccharide-Induced Neural Stem Cells by Regulating NF-KB and Phosphorylation of MAPK/P38/Erk Pathways.
MiRNA-223-3p Affects Mantle Cell Lymphoma Development by Regulating the CHUK/NF-ƘB2 Signaling Pathway.
The Significance of HOXC11 and LSH in Survival Prediction in Gastric Adenocarcinoma.
Network pharmacology-guided mechanism study uncovers inhibitory effect of Mahuang Decoction on lung cancer growth by impeding Akt/ERK signaling pathways.
Myosin 1b promotes migration, invasion and glycolysis in cervical cancer via ERK/HIF-1α pathway.
Sevoflurane prevents pulmonary vascular remodeling and right ventricular dysfunction in pulmonary arterial hypertension in rats.
Dura cells in the etiopathogenesis of Crouzon syndrome: the effects of FGFR2 mutations in the dura cells on the proliferation of osteoblasts through the hippo/YAP mediated transcriptional regulation pathway.
Schisandrin C attenuates renal damage in diabetic nephropathy by regulating macrophage polarization.
Overexpression of the lncRNA AC012213.3 Promotes Proliferation, Migration and Invasion of Breast Cancer via RAD54B/PI3K/AKT Axis and is Associated with Worse Patient Prognosis.
Calcitriol Alleviates MPP(+)- and MPTP-Induced Parthanatos Through the VDR/PARP1 Pathway in the Model of Parkinson's Disease.
ZNF750 exerted its Antitumor Action in Oral Squamous Cell Carcinoma by regulating E2F2.
LncRNA TMEM220-AS1 suppresses hepatocellular carcinoma cell proliferation and invasion by regulating the TMEM220/β-catenin axis.
LncRNA MALAT1 was regulated by HPV16 E7 independently of pRB in cervical cancer cells.
Inositol hexaphosphate sensitizes hepatocellular carcinoma to oxaliplatin relating inhibition of CCN2-LRP6-β-catenin-ABCG1 signaling pathway.
Caspase-11-Mediated Hepatocytic Pyroptosis Promotes the Progression of Nonalcoholic Steatohepatitis.
SLC39A7 promotes malignant behaviors in glioma via the TNF-α-mediated NF-κB signaling pathway.
Demethylzelasteral inhibits proliferation and EMT via repressing Wnt/β-catenin signaling in esophageal squamous cell carcinoma.
CDK5 Knockdown inhibits proliferation and induces apoptosis and Cell Cycle Arrest in Human Glioblastoma.
Proteomic Analysis of the Alterations in Follicular Fluid Proteins During Oocyte Maturation in Humans.
Diosgenin From Dioscorea Nipponica Rhizoma Against Graves' Disease-On Network Pharmacology and Experimental Evaluation.
Exploring the Pharmacological Mechanisms of Xihuang Pills Against Prostate Cancer via Integrating Network Pharmacology and Experimental Validation In Vitro and In Vivo.
Proteomics Study Reveals the Anti-Depressive Mechanisms and the Compatibility Advantage of Chaihu-Shugan-San in a Rat Model of Chronic Unpredictable Mild Stress.
Punicalin Attenuates Breast Cancer-Associated Osteolysis by Inhibiting the NF-κB Signaling Pathway of Osteoclasts.
Baicalein Alleviates Osteoarthritis Progression in Mice by Protecting Subchondral Bone and Suppressing Chondrocyte Apoptosis Based on Network Pharmacology.
Chitosan Protects Immunosuppressed Mice Against Cryptosporidium parvum Infection Through TLR4/STAT1 Signaling Pathways and Gut Microbiota Modulation.
Integrated Network Pharmacology and Lipidomics to Reveal the Inhibitory Effect of Qingfei Oral Liquid on Excessive Autophagy in RSV-Induced Lung Inflammation.
Inhibiting YAP in Endothelial Cells From Entering the Nucleus Attenuates Blood-Brain Barrier Damage During Ischemia-Reperfusion Injury.
Acid-Sensing Ion Channel 1/Calpain1 Activation Impedes Macrophage ATP-Binding Cassette Protein A1-Mediated Cholesterol Efflux Induced by Extracellular Acidification.
Activation of TAF9 via Danshensu-Induced Upregulation of HDAC1 Expression Alleviates Non-alcoholic Fatty Liver Disease.
Enhancing Fatty Acids Oxidation via L-Carnitine Attenuates Obesity-Related Atrial Fibrillation and Structural Remodeling by Activating AMPK Signaling and Alleviating Cardiac Lipotoxicity.
CircEpc1 Promotes Ricin Toxin-Induced Inflammation via Activation of NF-κB and MAPK Signaling Pathways by Sponging miR-5114.
Screening and Functional Analysis of TEK Mutations in Chinese Children With Primary Congenital Glaucoma.
circKLF4 Upregulates Klf4 and Endoglin to Promote Odontoblastic Differentiation of Mouse Dental Papilla Cells via Sponging miRNA-1895 and miRNA-5046.
Trametinib Inhibits the Growth and Aerobic Glycolysis of Glioma Cells by Targeting the PKM2/c-Myc Axis.
Dauricine Attenuates Vascular Endothelial Inflammation Through Inhibiting NF-κB Pathway.
The ALDH Family Contributes to Immunocyte Infiltration, Proliferation and Epithelial-Mesenchymal Transformation in Glioma.
β2-Adrenergic Receptor Enhances the Alternatively Activated Macrophages and Promotes Biliary Injuries Caused by Helminth Infection.
Characterization of Pathogenesis and Inflammatory Responses to Experimental Parechovirus Encephalitis.
The Effect of Ellagic Acid on Hepatic Lipid Metabolism and Antioxidant Activity in Mice.
SARS-CoV-2 Nsp5 Activates NF-κB Pathway by Upregulating SUMOylation of MAVS.
Rhein Relieves Oxidative Stress in an Aβ(1-42) Oligomer-Burdened Neuron Model by Activating the SIRT1/PGC-1α-Regulated Mitochondrial Biogenesis.
Anlotinib Inhibits PFKFB3-Driven Glycolysis in Myofibroblasts to Reverse Pulmonary Fibrosis.
Mechanisms Underlying Gastrodin Alleviating Vincristine-Induced Peripheral Neuropathic Pain.
Identification of a Novel Gene Correlated With Vascular Smooth Muscle Cells Proliferation and Migration in Chronic Thromboembolic Pulmonary Hypertension.
Morchella importuna Flavones Improve Intestinal Integrity in Dextran Sulfate Sodium-Challenged Mice.
Probiotic Interventions Alleviate Food Allergy Symptoms Correlated With Cesarean Section: A Murine Model.
High-Salt Attenuates the Efficacy of Dapagliflozin in Tubular Protection by Impairing Fatty Acid Metabolism in Diabetic Kidney Disease.
Tetrandrine Modulates Rheb-mTOR Signaling-Mediated Selective Autophagy and Protects Pulmonary Fibrosis.
MIR337-3p Enhances Mycobacterial Pathogenicity Involving TLR4/MYD88 and STAT3 Signals, Impairing VDR Antimicrobial Response and Fast-Acting Immunity.
Paeoniflorin Suppresses TBHP-Induced Oxidative Stress and Apoptosis in Human Umbilical Vein Endothelial Cells via the Nrf2/HO-1 Signaling Pathway and Improves Skin Flap Survival.
β-Adrenergic Receptor Inhibitor and Oncolytic Herpesvirus Combination Therapy Shows Enhanced Antitumoral and Antiangiogenic Effects on Colorectal Cancer.
Polysaccharides Extracted From Panax Ginseng C.A. Mey Enhance Complement Component 4 Biosynthesis in Human Hepatocytes.
Berberine Reduces Lipid Accumulation by Promoting Fatty Acid Oxidation in Renal Tubular Epithelial Cells of the Diabetic Kidney.
Clozapine Induced Disturbances in Hepatic Glucose Metabolism: The Potential Role of PGRMC1 Signaling.
Association of Pericyte Loss With Microthrombosis After Subarachnoid Hemorrhage in ApoE-Deficient Mice.
Protective Effect of Oxytocin on Ventilator-Induced Lung Injury Through NLRP3-Mediated Pathways.
Ddb1 Is Essential for the Expansion of CD4(+) Helper T Cells by Regulating Cell Cycle Progression and Cell Death.
Identification of Potential Prognostic Biomarker for Predicting Survival in Multiple Myeloma Using Bioinformatics Analysis and Experiments.
The Downregulation of eIF3a Contributes to Vemurafenib Resistance in Melanoma by Activating ERK via PPP2R1B.
Inhibition of the Inflammasome Activity of NLRP3 Attenuates HDM-Induced Allergic Asthma.
Exploring the Critical Components and Therapeutic Mechanisms of Perilla frutescens L. in the Treatment of Chronic Kidney Disease via Network Pharmacology.
Weighted Gene Co-Expression Network Analysis Identifies ANGPTL4 as a Key Regulator in Diabetic Cardiomyopathy via FAK/SIRT3/ROS Pathway in Cardiomyocyte.
Novel Pyrazolo[3,4-b] Pyridine Derivative (HLQ2g) Attenuates Hypoxic Pulmonary Hypertension via Restoring cGKI Expression and BMP Signaling Pathway.
miR-25 Regulates Gastric Cancer Cell Growth and Apoptosis by Targeting EGR2.
An Escherichia coli Effector Protein EspF May Induce Host DNA Damage via Interaction With SMC1.
Lidocaine Promoted Ferroptosis by Targeting miR-382-5p /SLC7A11 Axis in Ovarian and Breast Cancer.
Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke.
c-Myc Upregulated by High Glucose Inhibits HaCaT Differentiation by S100A6 Transcriptional Activation.
High Mobility Group Box 1 (HMGB1) Induces Toll-Like Receptor 4-Mediated Production of the Immunosuppressive Protein Galectin-9 in Human Cancer Cells.
Effects of Sodium Ferulate on Cardiac Hypertrophy Are via the CaSR-Mediated Signaling Pathway.
SARS-CoV-2 Membrane Protein Inhibits Type I Interferon Production Through Ubiquitin-Mediated Degradation of TBK1.
Astragaloside IV Inhibits Galactose-Deficient IgA1 Secretion via miR-98-5p in Pediatric IgA Nephropathy.
Circ_0040039 May Aggravate Intervertebral Disk Degeneration by Regulating the MiR-874-3p-ESR1 Pathway.
A New Chalcone Derivative C49 Reverses Doxorubicin Resistance in MCF-7/DOX Cells by Inhibiting P-Glycoprotein Expression.
Nicotine Causes Mitochondrial Dynamics Imbalance and Apoptosis Through ROS Mediated Mitophagy Impairment in Cardiomyocytes.
Quercetin Attenuates Trauma-Induced Heterotopic Ossification by Tuning Immune Cell Infiltration and Related Inflammatory Insult.
TOX Acts as a Tumor Suppressor by Inhibiting mTOR Signaling in Colorectal Cancer.
Identification of a RAD52 Inhibitor Inducing Synthetic Lethality in BRCA2-Deficient Cancer Cells.
BYHWD Alleviates Inflammatory Response by NIK-Mediated Repression of the Noncanonical NF-κB Pathway During ICH Recovery.
Increased Angiogenin Expression Correlates With Radiation Resistance and Predicts Poor Survival for Patients With Nasopharyngeal Carcinoma.
Meteorin-Like Ameliorates β Cell Function by Inhibiting β Cell Apoptosis of and Promoting β Cell Proliferation via Activating the WNT/β-Catenin Pathway.
Duck Hepatitis A Virus Type 1 Induces eIF2α Phosphorylation-Dependent Cellular Translation Shutoff via PERK/GCN2.
In Vivo Inhibition of MicroRNA-326 in a NOD.H-2(h4) Mouse Model of Autoimmune Thyroiditis.
IR-61 Improves Voiding Function via Mitochondrial Protection in Diabetic Rats.
Bortezomib Sustains T Cell Function by Inducing miR-155-Mediated Downregulation of SOCS1 and SHIP1.
Inhibition of Shear-Induced Platelet Aggregation by Xueshuantong via Targeting Piezo1 Channel-Mediated Ca(2+) Signaling Pathway.
SFTSV Infection Induced Interleukin-1β Secretion Through NLRP3 Inflammasome Activation.
PHB2 promotes tumorigenesis via RACK1 in non-small cell lung cancer.
Necroptosis pathway blockage attenuates PFKFB3 inhibitor-induced cell viability loss and genome instability in colorectal cancer cells.
Targeting of glioma stem-like cells with a parthenolide derivative ACT001 through inhibition of AEBP1/PI3K/AKT signaling.
Local administration of liposomal-based Srpx2 gene therapy reverses pulmonary fibrosis by blockading fibroblast-to-myofibroblast transition.
KAT6A, a novel regulator of β-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1.
Aurka loss in CD19(+) B cells promotes megakaryocytopoiesis via IL-6/STAT3 signaling-mediated thrombopoietin production.
Ese-3 contributes to colon cancer progression by downregulating EHD2 and transactivating INPP4B.
Cardiac telocytes inhibit cardiac microvascular endothelial cell apoptosis through exosomal miRNA-21-5p-targeted cdip1 silencing to improve angiogenesis following myocardial infarction.
Deferoxamine Counteracts Cisplatin Resistance in A549 Lung Adenocarcinoma Cells by Increasing Vulnerability to Glutamine Deprivation-Induced Cell Death.
Phospholipid Phosphatase 4 as a Driver of Malignant Glioma and Pancreatic Adenocarcinoma.
Modulated TRPC1 Expression Predicts Sensitivity of Breast Cancer to Doxorubicin and Magnetic Field Therapy: Segue Towards a Precision Medicine Approach.
ITGA5 Predicts Dual-Drug Resistance to Temozolomide and Bevacizumab in Glioma.
Prognostic Value and Correlation With Tumor Immune Infiltration of a Novel Metabolism-Related Gene Signature in Pancreatic Cancer.
Autophagy-Induced HDAC6 Activity During Hypoxia Regulates Mitochondrial Energy Metabolism Through the β-Catenin/COUP-TFII Axis in Hepatocellular Carcinoma Cells.
Purified Vitexin Compound 1 Serves as a Promising Antineoplastic Agent in Ovarian Cancer.
Identification of Glycolysis-Related lncRNAs and the Novel lncRNA WAC-AS1 Promotes Glycolysis and Tumor Progression in Hepatocellular Carcinoma.
Honokiol Suppresses Perineural Invasion of Pancreatic Cancer by Inhibiting SMAD2/3 Signaling.
The Anti-Colon Cancer Effects of Essential Oil of Curcuma phaeocaulis Through Tumour Vessel Normalisation.
Downregulation of miR-142a Contributes to the Enhanced Anti-Apoptotic Ability of Murine Chronic Myelogenous Leukemia Cells.
Cystatin-B Negatively Regulates the Malignant Characteristics of Oral Squamous Cell Carcinoma Possibly Via the Epithelium Proliferation/Differentiation Program.
NEK7 Promotes Pancreatic Cancer Progression And Its Expression Is Correlated With Poor Prognosis.
Transcriptomic Analyses of the Adenoma-Carcinoma Sequence Identify Hallmarks Associated With the Onset of Colorectal Cancer.
The EIF4A3/CASC2/RORA Feedback Loop Regulates the Aggressive Phenotype in Glioblastomas.
Aeromonas sobria Induces Proinflammatory Cytokines Production in Mouse Macrophages via Activating NLRP3 Inflammasome Signaling Pathways.
Transcriptomic Analyses Reveal B-Cell Translocation Gene 2 as a Potential Therapeutic Target in Ovarian Cancer.
The RNA-Binding Protein NELFE Promotes Gastric Cancer Growth and Metastasis Through E2F2.
Long Non-Coding RNA LINC00467 Correlates to Poor Prognosis and Aggressiveness of Breast Cancer.
N6-Methyladenosine Modification of LncRNA DUXAP9 Promotes Renal Cancer Cells Proliferation and Motility by Activating the PI3K/AKT Signaling Pathway.
Downregulation of GLYAT Facilitates Tumor Growth and Metastasis and Poor Clinical Outcomes Through the PI3K/AKT/Snail Pathway in Human Breast Cancer.
MiR-454-3p Promotes Oxaliplatin Resistance by Targeting PTEN in Colorectal Cancer.
Asparagine Synthetase-Mediated l-Asparagine Metabolism Disorder Promotes the Perineural Invasion of Oral Squamous Cell Carcinoma.
Discovering and Characterizing of Survivin Dominant Negative Mutants With Stronger Pro-apoptotic Activity on Cancer Cells and CSCs.
HOXA5 Is Recognized as a Prognostic-Related Biomarker and Promotes Glioma Progression Through Affecting Cell Cycle.
TFEB Promotes Prostate Cancer Progression via Regulating ABCA2-Dependent Lysosomal Biogenesis.
Identification of Hub Genes Associated With Sensitivity of 5-Fluorouracil Based Chemotherapy for Colorectal Cancer by Integrated Bioinformatics Analysis.
IFN-γ facilitates liver fibrogenesis by CD161(+)CD4(+) T cells through a regenerative IL-23/IL-17 axis in chronic hepatitis B virus infection.
Epigallocatechin-3-gallate inhibits proliferation and triggers apoptosis in colon cancer via the hedgehog/phosphoinositide 3-kinase pathways.
SARS-CoV-2 ORF9b antagonizes type I and III interferons by targeting multiple components of the RIG-I/MDA-5-MAVS, TLR3-TRIF, and cGAS-STING signaling pathways.
Subicular Caspase-1 Contributes to Pharmacoresistance in Temporal Lobe Epilepsy.
Yangonin modulates lipid homeostasis, ameliorates cholestasis and cellular senescence in alcoholic liver disease via activating nuclear receptor FXR.
Spindle and kinetochore-associated complex subunit 3 (SKA3) promotes stem cell-like properties of hepatocellular carcinoma cells through activating Notch signaling pathway.
Actin-binding protein, IQGAP1, regulates LPS-induced RPMVECs hyperpermeability and ICAM-1 upregulation via Rap1/Src signalling pathway.
HOXA5 induces M2 macrophage polarization to attenuate carotid atherosclerosis by activating MED1.
AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence.
Disruption of Circadian Clocks Promotes Progression of Alzheimer's Disease in Diabetic Mice.
Postconditioning with Sevoflurane or Propofol Alleviates Lipopolysaccharide-Induced Neuroinflammation but Exerts Dissimilar Effects on the NR2B Subunit and Cognition.
Melatonin and doxorubicin synergistically enhance apoptosis via autophagy-dependent reduction of AMPKα1 transcription in human breast cancer cells.
Bruton's tyrosine kinase regulates macrophage‑induced inflammation in the diabetic kidney via NLRP3 inflammasome activation.
Environmental Microcystin exposure in underlying NAFLD-induced exacerbation of neuroinflammation, blood-brain barrier dysfunction, and neurodegeneration are NLRP3 and S100B dependent.
Spata2 Knockdown Exacerbates Brain Inflammation via NF-κB/P38MAPK Signaling and NLRP3 Inflammasome Activation in Cerebral Ischemia/Reperfusion Rats.
Long noncoding RNA ANRIL knockdown attenuates neuroinflammation following ischemic stroke via suppressing the expression of NF-κB in vitro and in vivo.
KDELR2 promotes breast cancer proliferation via HDAC3-mediated cell cycle progression.
Gastrodin protects against high glucose-induced cardiomyocyte toxicity via GSK-3β-mediated nuclear translocation of Nrf2.
An Antioxidant Sesquiterpene Inhibits Osteoclastogenesis Via Blocking IPMK/TRAF6 and Counteracts OVX-Induced Osteoporosis in Mice.
Long non-coding RNA DUXAP9 promotes hepatocellular carcinoma cell stemness via directly interacting with sox9.
Compound essential oils relieve oxidative stress caused by PM(2) (.5) exposure by inhibiting autophagy through the AMPK/mTOR pathway.
CTR9-mediated JAK2/STAT3 pathway promotes the proliferation, migration, and invasion of human glioma cells.
MiR-100-5p regulates cardiac hypertrophy through activation of autophagy by targeting mTOR.
Bone marrow mesenchymal stem cell-derived exosomes induce the Th17/Treg imbalance in immune thrombocytopenia through miR-146a-5p/IRAK1 axis.
Bovine viral diarrhea virus NS4B protein interacts with 2CARD of MDA5 domain and negatively regulates the RLR-mediated IFN-β production.
Docosahexaenoic acid activates the Nrf2 signaling pathway to alleviate impairment of spleen cellular immunity in intrauterine growth restricted rat pups.
Cinnabar protects serum-nutrient starvation induced apoptosis by improving intracellular oxidative stress and inhibiting the expression of CHOP and PERK.
miR-29c-3p regulates TET2 expression and inhibits autophagy process in Parkinson's disease models.
DNM3OS regulates GAPDH expression and influences the molecular pathogenesis of Huntington's disease.
Exogenous H(2) S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
Expression of TCF3 in Wilms' tumor and its regulatory role in kidney tumor cell viability, migration and apoptosis in vitro.
Identification and validation of EPHX2 as a prognostic biomarker in hepatocellular carcinoma.
Salusin‑β participates in high glucose‑induced HK‑2 cell ferroptosis in a Nrf‑2‑dependent manner.
Lack of Mof reduces acute liver injury by enhancing transcriptional activation of Igf1.
PKC-β/Alox5 axis activation promotes Bcr-Abl-independent TKI-resistance in chronic myeloid leukemia.
Propofol inhibited gastric cancer proliferation via the hsa-miR-328-3p/STAT3 pathway.
The piRNA pathway is essential for generating functional oocytes in golden hamsters.
RNA N(6) -methyladenosine modification suppresses replication of rice black streaked dwarf virus and is associated with virus persistence in its insect vector.
Autophagy promotes invadopodia formation in human ovarian cancer cells via the p62-extracellular signal-regulated kinase 1/2 pathway.
Low-dose repeated exposure to chemical surfactant impairs corneal epithelium: When personal cleaning products entering the eye.
Hsa_circ_0006232 promotes laryngeal squamous cell cancer progression through FUS-mediated EZH2 stabilization.
Total Flavonoids of Engelhardia roxburghiana Wall. Leaves Alleviated Foam Cells Formation through AKT/mTOR-Mediated Autophagy in the Progression of Atherosclerosis.
High mobility group box 1 mediates inflammatory response of astrocytes via cyclooxygenase 2/prostaglandin E2 signaling following spinal cord injury.
Ruyiping extract reduces lung metastasis in triple negative breast cancer by regulating macrophage polarization.
Quadruple-editing of the MAPK and PI3K pathways effectively blocks the progression of KRAS-mutated colorectal cancer cells.
METTL14 promotes glomerular endothelial cell injury and diabetic nephropathy via m6A modification of α-klotho.
Genomic and epigenomic evolution of acquired resistance to combination therapy in esophageal squamous cell carcinoma.
Viral targeting of glioblastoma stem cells with patient-specific genetic and post-translational p53 deregulations.
A pair of long intergenic non-coding RNA LINC00887 variants act antagonistically to control Carbonic Anhydrase IX transcription upon hypoxia in tongue squamous carcinoma progression.
Cannabidiol Effectively Promoted Cell Death in Bladder Cancer and the Improved Intravesical Adhesion Drugs Delivery Strategy Could Be Better Used for Treatment.
ACLY ubiquitination by CUL3-KLHL25 induces the reprogramming of fatty acid metabolism to facilitate iTreg differentiation.
Suppressors of cytokine signaling 1 protein in a regenerative model of the Gekko japonicus spinal cord.
Stimulation of ROS Generation by Extract of Warburgia ugandensis Leading to G(0)/G(1) Cell Cycle Arrest and Antiproliferation in A549 Cells.
Identification and Characterization of Eimeria tenella Microneme Protein (EtMIC8).
HIF-1α/JMJD1A signaling regulates inflammation and oxidative stress following hyperglycemia and hypoxia-induced vascular cell injury.
Adipose expression of CREB3L3 modulates body weight during obesity.
Exosomal microRNA-588 from M2 polarized macrophages contributes to cisplatin resistance of gastric cancer cells.
Dual Inhibition of Endoplasmic Reticulum Stress and Oxidation Stress Manipulates the Polarization of Macrophages under Hypoxia to Sensitize Immunotherapy.
Identification of genes and pathways leading to metastasis and poor prognosis in melanoma.
The Ginsenoside Rg(1) Rescues Mitochondrial Disorders in Aristolochic Acid-Induced Nephropathic Mice.
Anti-osteosarcoma effect of antiserum against cross antigen TPD52 between osteosarcoma and Trichinella spiralis.
MEST promotes lung cancer invasion and metastasis by interacting with VCP to activate NF-κB signaling.
Potent Inhibition of HIF1α and p300 Interaction by a Constrained Peptide Derived from CITED2.
Discovery of a Potent Glutathione Peroxidase 4 Inhibitor as a Selective Ferroptosis Inducer.
Perinatal low-dose bisphenol AF exposure impairs synaptic plasticity and cognitive function of adult offspring in a sex-dependent manner.
Genistein exhibits therapeutic potential for PCOS mice via the ER-Nrf2-Foxo1-ROS pathway.
Isonicotinylation is a histone mark induced by the anti-tuberculosis first-line drug isoniazid.
β-adrenergic receptor inhibition enhances oncolytic herpes virus propagation through STAT3 activation in gastric cancer.
Ultramicronized Palmitoylethanolamide Inhibits NLRP3 Inflammasome Expression and Pro-Inflammatory Response Activated by SARS-CoV-2 Spike Protein in Cultured Murine Alveolar Macrophages.
RIOK2 Inhibitor NSC139021 Exerts Anti-Tumor Effects on Glioblastoma via Inducing Skp2-Mediated Cell Cycle Arrest and Apoptosis.
Lactobacillus johnsonii L531 Alleviates the Damage Caused by Salmonella Typhimurium via Inhibiting TLR4, NF-κB, and NLRP3 Inflammasome Signaling Pathways.
KIF15 upregulation promotes leiomyosarcoma cell growth via promoting USP15-mediated DEK deubiquitylation.
UBE2S promotes the progression and Olaparib resistance of ovarian cancer through Wnt/β-catenin signaling pathway.
HSF1 is involved in suppressing A1 phenotype conversion of astrocytes following spinal cord injury in rats.
MiR-200c-3p promotes ox-LDL-induced endothelial to mesenchymal transition in human umbilical vein endothelial cells through SMAD7/YAP pathway.
Harmine-inspired design and synthesis of benzo[d]imidazo[2,1-b]thiazole derivatives bearing 1,3,4-oxadiazole moiety as potential tumor suppressors.
Hypoxia increases KIAA1199/CEMIP expression and enhances cell migration in pancreatic cancer.
Genetically variant human pluripotent stem cells selectively eliminate wild-type counterparts through YAP-mediated cell competition.
Ketamine ameliorates depressive-like behaviors in mice through increasing glucose uptake regulated by the ERK/GLUT3 signaling pathway.
A standardized extract of Asparagus officinalis stem improves HSP70-mediated redox balance and cell functions in bovine cumulus-granulosa cells.
2,5-dimethyl celecoxib induces apoptosis and autophagy via activation of ROS/JNK axis in nasopharyngeal carcinoma cells.
Defining the Cholesterol Lowering Mechanism of Bergamot (Citrus bergamia) Extract in HepG2 and Caco-2 Cells.
Targeting chromosome trisomy for chromosome editing.
Baicalein Enhances the Effect of Acarbose on the Improvement of Nonalcoholic Fatty Liver Disease Associated with Prediabetes via the Inhibition of De Novo Lipogenesis.
H(2)S alleviates aortic aneurysm and dissection: Crosstalk between transforming growth factor 1 signaling and NLRP3 inflammasome.
Silica nanoparticles inhibiting the differentiation of round spermatid and chromatin remodeling of haploid period via MIWI in mice.
LncAY controls BMI1 expression and activates BMI1/Wnt/β-catenin signaling axis in hepatocellular carcinoma.
Sitagliptin attenuates endothelial dysfunction independent of its blood glucose controlling effect.
LncRNA OIP5-AS1 inhibits ferroptosis in prostate cancer with long-term cadmium exposure through miR-128-3p/SLC7A11 signaling.
Yeast Shells Encapsulating Adjuvant AS04 as an Antigen Delivery System for a Novel Vaccine against Toxoplasma Gondii.
Radiation-Induced Autophagy in Human Pancreatic Cancer Cells is Critically Dependent on G2 Checkpoint Activation: A Mechanism of Radioresistance in Pancreatic Cancer.
Exosomes derived from induced pluripotent stem cells suppresses M2-type macrophages during pulmonary fibrosis via miR-302a-3p/TET1 axis.
JNK inhibition alleviates delayed neurocognitive recovery after surgery by limiting microglia pyroptosis.
Thymus quinquecostatus Celak. ameliorates cerebral ischemia-reperfusion injury via dual antioxidant actions: Activating Keap1/Nrf2/HO-1 signaling pathway and directly scavenging ROS.
Lactobacillus casei relieves liver injury by regulating immunity and suppression of the enterogenic endotoxin-induced inflammatory response in rats cotreated with alcohol and iron.
Characteristics and clinical significance of polyploid giant cancer cells in laryngeal carcinoma.
SETD3 Downregulation Mediates PTEN Upregulation-Induced Ischemic Neuronal Death Through Suppression of Actin Polymerization and Mitochondrial Function.
Systematic screening identifies a TEAD4-S100A13 axis modulating cisplatin sensitivity of oral squamous cell carcinoma cells.
Alpha-ketoglutarate ameliorates pressure overload-induced chronic cardiac dysfunction in mice.
CTHRC1 Knockdown Promotes Inflammatory Responses Partially by p38 MAPK Activation in Human Periodontal Ligament Cells.
Interleukin-38 Suppresses Cell Migration and Proliferation and Promotes Apoptosis of Colorectal Cancer Cell Through Negatively Regulating Extracellular Signal-Regulated Kinases Signaling.
High-mobility group AT-Hook 1 mediates the role of nuclear factor I/X in osteogenic differentiation through activating canonical Wnt signaling.
Autographa Californica Multiple Nucleopolyhedrovirus orf13 Is Required for Efficient Nuclear Egress of Nucleocapsids.
An enzyme-responsive Gp1a-hydrogel for skin wound healing.
Imbalanced inflammatory response in subchronic arsenic-induced liver injury and the protective effects of Ginkgo biloba extract in rats: Potential role of cytokines mediated cell-cell interactions.
5-IP(7) is a GPCR messenger mediating neural control of synaptotagmin-dependent insulin exocytosis and glucose homeostasis.
Dynamin-related protein 1 regulates substrate oxidation in skeletal muscle by stabilizing cellular and mitochondrial calcium dynamics.
Arsenic Trioxide Combining Leflunomide Activates Nrf2-ARE-HO-1 Signaling Pathway and Protects Heart Xenografts.
MicroRNA ssc-miR-124a exhibits antiviral activity against porcine reproductive and respiratory syndrome virus via suppression of host genes CD163.
TRIM21 negatively regulates Corynebacterium pseudotuberculosis-induced inflammation and is critical for the survival of C. pseudotuberculosis infected C57BL6 mice.
Reactive oxygen species induced by uric acid promote NRK‑52E cell apoptosis through the NEK7‑NLRP3 signaling pathway.
Hsa_circ_0004058 inhibits apoptosis of SRA01/04 cells by promoting autophagy via miR-186/ATG7 axis.
Advanced Maternal Age-associated SIRT1 Deficiency Compromises Trophoblast Epithelial-Mesenchymal Transition through an Increase in Vimentin Acetylation.
Activation of angiotensin-converting enzyme 2/angiotensin (1-7)/mas receptor axis triggers autophagy and suppresses microglia proinflammatory polarization via forkhead box class O1 signaling.
Peptides derived from viral glycoprotein Gc Inhibit infection of severe fever with thrombocytopenia syndrome virus.
RSL3 enhances the antitumor effect of cisplatin on prostate cancer cells via causing glycolysis dysfunction.
PIKE-A promotes glioblastoma growth by driving PPP flux through increasing G6PD expression mediated by phosphorylation of STAT3.
Dihydroartemisinin regulates lipid droplet metabolism in hepatic stellate cells by inhibiting lncRNA-H19-induced AMPK signal.
LncRNA-Malat1 down-regulates miR-211-5p expression to promote neuronal damage from cerebral ischemia reperfusion injury.
REM Sleep Deprivation Impairs Learning and Memory by Decreasing Brain O-GlcNAc Cycling in Mouse.
Ginsenoside Rg1 prevents bone marrow mesenchymal stem cell senescence via NRF2 and PI3K/Akt signaling.
A purified human platelet pellet lysate rich in neurotrophic factors and antioxidants repairs and protects corneal endothelial cells from oxidative stress.
Panax notoginseng saponins reduces the cisplatin-induced acute renal injury by increasing HIF-1α/BNIP3 to inhibit mitochondrial apoptosis pathway.
Deletion of ribosomal paralogs Rpl39 and Rpl39l compromises cell proliferation via protein synthesis and mitochondrial activity.
Design, synthesis and antitumor evaluation of novel chiral diaryl substituted azetidin-2-one derivatives as tubulin polymerization inhibitors.
Transcription factor POU4F2 promotes colorectal cancer cell migration and invasion through hedgehog-mediated epithelial-mesenchymal transition.
ERK1/2 mitogen-activated protein kinase mediates downregulation of intestinal tight junction proteins in heat stress-induced IBD model in pig.
Aberrant expression of SNHG12 contributes to N, N-dimethylformamide-induced hepatic apoptosis both in short-term and long-term DMF exposure.
Protocols for Characterization of Cdk5 Kinase Activity.
CENPA promotes clear cell renal cell carcinoma progression and metastasis via Wnt/β-catenin signaling pathway.
sTNFRII-Fc modification protects human UC-MSCs against apoptosis/autophagy induced by TNF-α and enhances their efficacy in alleviating inflammatory arthritis.
Glycogen synthase kinase 3 drives thymocyte egress by suppressing β-catenin activation of Akt.
d-mannose attenuates lipopolysaccharide-induced osteolysis via CPT1A-Mediated lipid metabolic regulation in macrophages.
TDAG51 induces renal interstitial fibrosis through modulation of TGF-β receptor 1 in chronic kidney disease.
Sulforaphane downregulated fatty acid synthase and inhibited microtubule-mediated mitophagy leading to apoptosis.
Tetrahedral Framework Nucleic Acid Delivered RNA Therapeutics Significantly Attenuate Pancreatic Cancer Progression via Inhibition of CTR1-Dependent Copper Absorption.
Leojaponin inhibits NLRP3 inflammasome activation through restoration of autophagy via upregulating RAPTOR phosphorylation.
p53 transcriptionally regulates SQLE to repress cholesterol synthesis and tumor growth.
PFP@PLGA/Cu(12)Sb(4)S(13)-mediated PTT ablates hepatocellular carcinoma by inhibiting the RAS/MAPK/MT-CO1 signaling pathway.
Activation of G protein coupled estrogen receptor prevents chemotherapy-induced intestinal mucositis by inhibiting the DNA damage in crypt cell in an extracellular signal-regulated kinase 1- and 2- dependent manner.
ATP-binding cassette protein ABCF1 couples transcription and genome surveillance in embryonic stem cells through low-complexity domain.
Fructus Ligustri Lucidi aqueous extract promotes calcium balance and short-chain fatty acids production in ovariectomized rats.
Dysfunctional lactate metabolism in human alveolar type II cells from idiopathic pulmonary fibrosis lung explant tissue.
Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation.
FABP4 is an independent risk factor for lymph node metastasis and poor prognosis in patients with cervical cancer.
The overexpression of Tipe2 in CRC cells suppresses survival while endogenous Tipe2 accelerates AOM/DSS induced-tumor initiation.
Circular RNA circPRKCI contributes to malignant progression of T-cell acute lymphoblastic leukemia by modulating miR-20a-5p/SOX4 axis.
Glaesserella parasuis serotype 4 HPS4-YC disrupts the integrity of the swine tracheal epithelial barrier and facilitates bacterial translocation.
Layered Double Hydroxide Nanoparticles with Osteogenic Effects as miRNA Carriers to Synergistically Promote Osteogenesis of MSCs.
Metformin sensitises hepatocarcinoma cells to methotrexate by targeting dihydrofolate reductase.
ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis.
Synapse development is regulated by microglial THIK-1 K(+) channels.
Targeting CDC7 potentiates ATR-CHK1 signaling inhibition through induction of DNA replication stress in liver cancer.
Aronia melanocarpa polysaccharide ameliorates inflammation and aging in mice by modulating the AMPK/SIRT1/NF-κB signaling pathway and gut microbiota.
Unexpected Implication of SRP and AGO2 in Parkinson's Disease: Involvement in Alpha-Synuclein Biogenesis.
Thromboxane A(2) is involved in the development of hypertension in chronic kidney disease rats.
A systematic approach to decode the mechanism of Cornus in the treatment of hepatocellular carcinoma (HCC).
Antidepressant mechanism of catalpol: Involvement of the PI3K/Akt/Nrf2/HO-1 signaling pathway in rat hippocampus.
Pharmacological activation of SIRT1 by metformin prevented trauma-induced heterotopic ossification through inhibiting macrophage mediated inflammation.
TRIM46 contributes to high glucose-induced ferroptosis and cell growth inhibition in human retinal capillary endothelial cells by facilitating GPX4 ubiquitination.
The expression of IFN-β is suppressed by the viral 3D polymerase via its impact on PGAM5 expression during enterovirus D68 infection.
NLRP3 inflammasome blocked the glycolytic pathway via targeting to PKLR in arsenic-induced hepatic insulin resistance.
5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma.
HBeAg mediates inflammatory functions of macrophages by TLR2 contributing to hepatic fibrosis.
The Timing and Effects of Low-Dose Ethanol Treatment on Acetaminophen-Induced Liver Injury.
Revisiting astrocyte to neuron conversion with lineage tracing in vivo.
The interaction of S100A16 and GRP78 actives endoplasmic reticulum stress-mediated through the IRE1α/XBP1 pathway in renal tubulointerstitial fibrosis.
Shift in MSL1 alternative polyadenylation in response to DNA damage protects cancer cells from chemotherapeutic agent-induced apoptosis.
Vezatin regulates seizures by controlling AMPAR-mediated synaptic activity.
Sitagliptin activates the p62-Keap1-Nrf2 signalling pathway to alleviate oxidative stress and excessive autophagy in severe acute pancreatitis-related acute lung injury.
Triiodothyronine ameliorates silica-induced pulmonary inflammation and fibrosis in mice.
Effects of Bacillus subtilis on jejunal integrity, redox status, and microbial composition of intrauterine growth restriction suckling piglets.
Catalpol Weakens Depressive-like Behavior in Mice with Streptozotocin-induced Hyperglycemia via PI3K/AKT/Nrf2/HO-1 Signaling Pathway.
GRIM-19 inhibits proliferation and induces apoptosis in a p53-dependent manner in colorectal cancer cells through the SIRT7/PCAF/MDM2 axis.
EPS8 supports pancreatic cancer growth by inhibiting BMI1 mediated proteasomal degradation of ALDH7A1.
Harpagide alleviate neuronal apoptosis and blood-brain barrier leakage by inhibiting TLR4/MyD88/NF-κB signaling pathway in Angiotensin II-induced microglial activation in vitro.
Antagonizing effects of curcumin against mercury-induced autophagic death and trace elements disorder by regulating PI3K/AKT and Nrf2 pathway in the spleen.
Cadmium promotes apoptosis and inflammation via the circ08409/miR-133a/TGFB2 axis in bovine mammary epithelial cells and mouse mammary gland.
Cellular OCIAD2 protein is a proviral factor for hepatitis C virus replication.
Switch receptor T3/28 improves long-term persistence and antitumor efficacy of CAR-T cells.
Nitrate increases cisplatin chemosensitivity of oral squamous cell carcinoma via REDD1/AKT signaling pathway.
Hsa-miR-372-5p regulates the NIMA related kinase 7 and IL-1β release in NK/T-cell lymphoma.
D-mannose alleviates osteoarthritis progression by inhibiting chondrocyte ferroptosis in a HIF-2α-dependent manner.
Selenoprotein K deficiency-induced apoptosis: A role for calpain and the ERS pathway.
Curcumol inhibits the malignant progression of prostate cancer and regulates the PDK1/AKT/mTOR pathway by targeting miR‑9.
Protein kinase G signaling pathway is involved in sympathetically maintained pain by modulating ATP-sensitive potassium channels.
Interleukin-17 upregulation participates in the pathogenesis of heart failure in mice via NF-κB-dependent suppression of SERCA2a and Cav1.2 expression.
Oxidative stress-mediated apoptosis is involved in bisphenol S-induced reproductive toxicity in male C57BL/6 mice.
Propylparaben concentrations in the urine of women and adverse effects on ovarian function in mice in vivo and ovarian cells in vitro.
Proteasome inhibition induces macrophage apoptosis via mitochondrial dysfunction.
Rutaecarpine alleviates acute pancreatitis in mice and AR42J cells by suppressing the MAPK and NF-κB signaling pathways via calcitonin gene-related peptide.
Icariin attenuates renal fibrosis in chronic kidney disease by inhibiting interleukin-1β/transforming growth factor-β-mediated activation of renal fibroblasts.
NudCL2 is an autophagy receptor that mediates selective autophagic degradation of CP110 at mother centrioles to promote ciliogenesis.
A peptide CORO1C-47aa encoded by the circular noncoding RNA circ-0000437 functions as a negative regulator in endometrium tumor angiogenesis.
Environmental Pollutant Benzo[a]pyrene Upregulated Long Non-coding RNA HZ07 Inhibits Trophoblast Cell Migration by Inactivating PI3K/AKT/MMP2 Signaling Pathway in Recurrent Pregnancy Loss.
miR‑486‑5p suppresses gastric cancer cell growth and migration through downregulation of fibroblast growth factor 9.
Low-dose exposure to black carbon significantly increase lung injury of cadmium by promoting cellular apoptosis.
Gas6/Axl signaling pathway promotes proliferation, migration and invasion and inhibits apoptosis in A549 cells.
Metformin attenuates H(2)O(2)-induced osteoblast apoptosis by regulating SIRT3 via the PI3K/AKT pathway.
The anti-neoplastic activities of aloperine in HeLa cervical cancer cells are associated with inhibition of the IL-6-JAK1-STAT3 feedback loop.
Tau phosphorylation and OPA1 proteolysis are unrelated events: Implications for Alzheimer's Disease.
Chemical Constituents from the Rhizome of Ligusticum chuanxiong Hort. and Their Nrf2 Inducing Activity.
Chitotriosidase attenuates brain inflammation via HDAC3/NF-κB pathway in D-galactose and aluminum-induced rat model with cognitive impairments.
The differentiation state of the Schwann cell progenitor drives phenotypic variation between two contagious cancers.
Perfluorooctane sulfonate induces autophagy-dependent lysosomal membrane permeabilization by weakened interaction between tyrosinated alpha-tubulin and spinster 1.
Gastrodin promotes hippocampal neurogenesis via PDE9-cGMP-PKG pathway in mice following cerebral ischemia.
Comparative proteomics reveals Cryptosporidium parvum manipulation of the host cell molecular expression and immune response.
Trophoblast-derived interleukin 9 mediates immune cell conversion and contributes to maternal-fetal tolerance.
Dopamine receptor 2 downregulation and brain-derived neurotrophic factor upregulation in the paraventricular nucleus are correlated with brown adipose tissue thermogenesis in rats with bilateral substantia nigra lesions.
miRNA-223-3p modulates ibrutinib resistance through regulation of the CHUK/Nf-κb signaling pathway in mantle cell lymphoma.
Isoliquiritigenin alleviates LPS/ D-GalN-induced acute liver failure by activating the PGC-1α/ Nrf2 pathway to reduce oxidative stress and inflammatory response.
Functional role of galectin-9 in directing human innate immune reactions to Gram-negative bacteria and T cell apoptosis.
The CCAAT-binding complex mediates azole susceptibility of Aspergillus fumigatus by suppressing SrbA expression and cleavage.
Ultrathin 2D Titanium Carbide MXene (Ti(3) C(2) T(x) ) Nanoflakes Activate WNT/HIF-1α-Mediated Metabolism Reprogramming for Periodontal Regeneration.
DNMT1-induced miR-378a-3p silencing promotes angiogenesis via the NF-κB signaling pathway by targeting TRAF1 in hepatocellular carcinoma.
High throughput sequencing of whole transcriptome and construct of ceRNA regulatory network in RD cells infected with enterovirus D68.
Betaine alleviates right ventricular failure via regulation of Rho A/ROCK signaling pathway in rats with pulmonary arterial hypertension.
Discovery of a potent MLL1 and WDR5 protein-protein interaction inhibitor with in vivo antitumor activity.
NOX4-derived ROS-induced overexpression of FOXM1 regulates aerobic glycolysis in glioblastoma.
Photobiomodulation inhibits the activation of neurotoxic microglia and astrocytes by inhibiting Lcn2/JAK2-STAT3 crosstalk after spinal cord injury in male rats.
Ex vivo to in vivo extrapolation of syringic acid and ferulic acid as grape juice proxies for endothelium-dependent vasodilation: Redefining vasoprotective resveratrol of the French paradox.
WFS1 functions in ER export of vesicular cargo proteins in pancreatic β-cells.
Hyaluronic acid hydrogel encapsulated BMP-14-modified ADSCs accelerate cartilage defect repair in rabbits.
Taxifolin retards the D-galactose-induced aging process through inhibiting Nrf2-mediated oxidative stress and regulating the gut microbiota in mice.
Metformin Improves Stemness of Human Adipose-Derived Stem Cells by Downmodulation of Mechanistic Target of Rapamycin (mTOR) and Extracellular Signal-Regulated Kinase (ERK) Signaling.
Structure-Based Discovery of Potent CARM1 Inhibitors for Solid Tumor and Cancer Immunology Therapy.
Proteolysis-Targeting Chimera (PROTAC) Modification of Dovitinib Enhances the Antiproliferative Effect against FLT3-ITD-Positive Acute Myeloid Leukemia Cells.
Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion.
Effect of combination therapy with neural stem cell transplantation and teramethylpyrazine in rats following acute spinal cord injury.
HIF-1-regulated expression of calreticulin promotes breast tumorigenesis and progression through Wnt/β-catenin pathway activation.
The Protective Role of Yin-Yang 1 in Cardiac Injury and Remodeling After Myocardial Infarction.
Identification of proximal SUMO-dependent interactors using SUMO-ID.
Fluoride Stimulates Anxiety- and Depression-like Behaviors Associated with SIK2-CRTC1 Signaling Dysfunction.
Dendrobium officinale Polysaccharide Alleviates Intestinal Inflammation by Promoting Small Extracellular Vesicle Packaging of miR-433-3p.
Role of Epigallocatechin Gallate in Glucose, Lipid, and Protein Metabolism and L-Theanine in the Metabolism-Regulatory Effects of Epigallocatechin Gallate.
Exopolysaccharides from Bifidobacterium animalis Ameliorate Escherichia coli-Induced IPEC-J2 Cell Damage via Inhibiting Apoptosis and Restoring Autophagy.
Astragalus polysaccharide prevents ferroptosis in a murine model of experimental colitis and human Caco-2 cells via inhibiting NRF2/HO-1 pathway.
HMMR is a downstream target of FOXM1 in enhancing proliferation and partial epithelial-to-mesenchymal transition of bladder cancer cells.
3-Epipachysamine B suppresses proliferation and induces apoptosis of breast cancer cell via PI3K/AKT/mTOR signaling pathway.
Si-Wu-Tang facilitates ovarian function through improving ovarian microenvironment and angiogenesis in a mouse model of premature ovarian failure.
Protective effect of the effective part of Andrographis paniculata (Burm.f.) Nees on PM(2.5)-induced lung injury in rats by modulating the NF-κB pathway.
Yi-Qi-Jian-Pi formula modulates the PI3K/AKT signaling pathway to attenuate acute-on-chronic liver failure by suppressing hypoxic injury and apoptosis in vivo and in vitro.
Cutting Edge: Caspase-8 Is a Linchpin in Caspase-3 and Gasdermin D Activation to Control Cell Death, Cytokine Release, and Host Defense during Influenza A Virus Infection.
SARS-CoV-2 inhibits induction of the MHC class I pathway by targeting the STAT1-IRF1-NLRC5 axis.
Heat stress induces oxidative stress and activates the KEAP1-NFE2L2-ARE pathway in bovine endometrial epithelial cells†.
Xbp1s-Ddit3 promotes MCT-induced pulmonary hypertension.
The Mutational Landscape of PTK7 in Congenital Scoliosis and Adolescent Idiopathic Scoliosis.
Phase separation drives RNA virus-induced activation of the NLRP6 inflammasome.
Erythritol Improves Nonalcoholic Fatty Liver Disease by Activating Nrf2 Antioxidant Capacity.
AICAR enhances the cytotoxicity of PFKFB3 inhibitor in an AMPK signaling-independent manner in colorectal cancer cells.
Isorhapontigenin (ISO) inhibits EMT through FOXO3A/METTL14/VIMENTIN pathway in bladder cancer cells.
SAA1 is transcriptionally activated by STAT3 and accelerates renal interstitial fibrosis by inducing endoplasmic reticulum stress.
Competing endogenous RNA network associated with oxygen-induced retinopathy: Expression of the network and identification of the MALAT1/miR-124-3p/EGR1 regulatory axis.
A naturally occurring FXR agonist, alisol B 23-acetate, protects against renal ischemia-reperfusion injury.
Vps13D functions in a Pink1-dependent and Parkin-independent mitophagy pathway.
LncRNA NEAT1 mediates intestinal inflammation by regulating TNFRSF1B.
Deleterious impact of nerve growth factor precursor (proNGF) on bladder urothelial and smooth muscle cells.
Efficient Killing of Multidrug-Resistant Internalized Bacteria by AIEgens In Vivo.
Amelioration of Murine Macrophage Activation Syndrome by Monomethyl Fumarate in Both a Heme Oxygenase 1-Dependent and Heme Oxygenase 1-Independent Manner.
Elevated type I interferon responses potentiate metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice.
Novel Japanese encephalitis virus NS1-based vaccine: Truncated NS1 fused with E. coli heat labile enterotoxin B subunit.
Cu-induced mitochondrial dysfunction is mediated by abnormal mitochondrial fission through oxidative stress in primary chicken embryo hepatocytes.
Changes of lipid profiles in human umbilical vein endothelial cells exposed to zirconia nanoparticles with or without the presence of free fatty acids.
Comparison of toxicity of Ti(3) C(2) and Nb(2) C Mxene quantum dots (QDs) to human umbilical vein endothelial cells.
Long non-coding RNA LEISA promotes progression of lung adenocarcinoma via enhancing interaction between STAT3 and IL-6 promoter.
miR-509-3p Suppresses Migration, Invasion, and Epithelial- Mesenchymal Transition in Melanoma Cells by Targeting Collagen Triple Helix Repeat Containing 1.
Cross-talk Between Histone and DNA Methylation Mediates Bone Loss in Hind Limb Unloading.
Long noncoding RNA DUXAP10 promotes the stemness of glioma cells by recruiting HuR to enhance Sox12 mRNA stability.
Glucose-dependent insulinotropic polypeptide modifies adipose plasticity and promotes beige adipogenesis of human omental adipose-derived stem cells.
Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer's disease.
Cholesterol 25-hydroxylase inhibits Senecavirus A replication by enzyme activity-dependent and independent mechanisms.
IL-1/IL-1R signaling induced by all-trans-retinal contributes to complement alternative pathway activation in retinal pigment epithelium.
Free Deoxycholic Acid Exacerbates Vascular Calcification in CKD through ER Stress-Mediated ATF4 Activation.
Long non-coding RNA PCA3 inhibits lipid accumulation and atherosclerosis through the miR-140-5p/RFX7/ABCA1 axis.
Anti-osteoporotic effects of alisol C 23-acetate via osteoclastogenesis inhibition.
Reversine suppresses osteosarcoma cell growth through targeting BMP-Smad1/5/8-mediated angiogenesis.
Inhibition of NLRP3 inflammasome ameliorates podocyte damage by suppressing lipid accumulation in diabetic nephropathy.
SREBP1/FASN/cholesterol axis facilitates radioresistance in colorectal cancer.
Multi-omics approaches identify SF3B3 and SIRT3 as candidate autophagic regulators and druggable targets in invasive breast carcinoma.
The role of PKA/PP2B-mediated Drp1 phosphorylation and the subsequent EGFR inhibition in Cr(VI)-induced premature senescence.
De novo purine biosynthesis is a major driver of chemoresistance in glioblastoma.
Oxidative stress induced by NOX2 contributes to neuropathic pain via plasma membrane translocation of PKCε in rat dorsal root ganglion neurons.
Redd1 knockdown prevents doxorubicin-induced cardiac senescence.
Circular RNA Calm4 Regulates Hypoxia-Induced Pulmonary Arterial Smooth Muscle Cells Pyroptosis via the Circ-Calm4/miR-124-3p/PDCD6 Axis.
Evaluation of Stable LifeAct-mRuby2- and LAMP1-NeonGreen Expressing A549 Cell Lines for Investigation of Aspergillus fumigatus Interaction with Pulmonary Cells.
High-fat diet impairs ferroptosis and promotes cancer invasiveness via downregulating tumor suppressor ACSL4 in lung adenocarcinoma.
FKBP52 overexpression accelerates hippocampal-dependent memory impairments in a tau transgenic mouse model.
Ribonucleic Acid Export 1 Is a Kinetochore-Associated Protein That Participates in Chromosome Alignment in Mouse Oocytes.
Effect of circular RNA, mmu_circ_0000296, on neuronal apoptosis in chronic cerebral ischaemia via the miR-194-5p/Runx3/Sirt1 axis.
Oocyte-secreted factors strongly stimulate sFRP4 expression in human cumulus cells.
Vertebrate cells differentially interpret ciliary and extraciliary cAMP.
Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells.
Evaluation of the nephrotoxicity and safety of low-dose aristolochic acid, extending to the use of Xixin (Asurum), by determination of methylglyoxal and d-lactate.
Downregulation of CD151 restricts VCAM-1 mediated leukocyte infiltration to reduce neurobiological injuries after experimental stroke.
Maternal folic acid supplementation prevents autistic behaviors in a rat model induced by prenatal exposure to valproic acid.
Ganoderma lucidum stimulates autophagy-dependent longevity pathways in Caenorhabditis elegans and human cells.
USP18 positively regulates innate antiviral immunity by promoting K63-linked polyubiquitination of MAVS.
The miR-378c-Samd1 circuit promotes phenotypic modulation of vascular smooth muscle cells and foam cells formation in atherosclerosis lesions.
Mir-139-5p inhibits glioma cell proliferation and progression by targeting GABRA1.
LncRNA ZNF674-AS1 regulates granulosa cell glycolysis and proliferation by interacting with ALDOA.
Exercise improves lipid droplet metabolism disorder through activation of AMPK-mediated lipophagy in NAFLD.
SET8 mitigates hepatic ischemia/reperfusion injury in mice by suppressing MARK4/NLRP3 inflammasome pathway.
Purification, structural characterization, and PCSK9 secretion inhibitory effect of the novel alkali-extracted polysaccharide from Cordyceps militaris.
Asenapine maleate inhibits angiotensin II-induced proliferation and activation of cardiac fibroblasts via the ROS/TGFβ1/MAPK signaling pathway.
Hyperactivation of HER2-SHCBP1-PLK1 axis promotes tumor cell mitosis and impairs trastuzumab sensitivity to gastric cancer.
trans-Fatty acids promote p53-dependent apoptosis triggered by cisplatin-induced DNA interstrand crosslinks via the Nox-RIP1-ASK1-MAPK pathway.
A subcellular map of the human kinome.
Berberine-photodynamic therapy sensitizes melanoma cells to cisplatin-induced apoptosis through ROS-mediated P38 MAPK pathways.
High fat suppresses SOD1 activity by reducing copper chaperone for SOD1 associated with neurodegeneration and memory decline.
Short-term but not long-term high fat diet feeding protects against pressure overload-induced heart failure through activation of mitophagy.
6-Gingerol attenuates ventilator-induced lung injury via anti-inflammation and antioxidative stress by modulating the PPARγ/NF-κBsignalling pathway in rats.
Total glycosides from stems of Cistanche tubulosa alleviate depression-like behaviors: bidirectional interaction of the phytochemicals and gut microbiota.
Androgen Receptor Stimulates Hexokinase 2 and Induces Glycolysis by PKA/CREB Signaling in Hepatocellular Carcinoma.
Circadian clock genes promote glioma progression by affecting tumour immune infiltration and tumour cell proliferation.
Nbs1-mediated DNA damage repair pathway regulates haematopoietic stem cell development and embryonic haematopoiesis.
MiR-520a-3p inhibits malignant progression of epithelial ovarian cancer by targeting SUV39H1 expression.
Oncogenic AURKA-enhanced N(6)-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells.
Chondrocyte ferroptosis contribute to the progression of osteoarthritis.
miR-130b-3p regulates M1 macrophage polarization via targeting IRF1.
Apoptosis inhibition is involved in improvement of sevoflurane-induced cognitive impairment following normobaric hyperoxia preconditioning in aged rats.
Regulation of ARL2 in colorectal cancer cell proliferation and tumorigenicity, and its negative association with AXL.
Three phytosterols from sweet potato inhibit MCF7-xenograft-tumor growth through modulating gut microbiota homeostasis and SCFAs secretion.
d-Mannose suppresses osteoarthritis development in vivo and delays IL-1β-induced degeneration in vitro by enhancing autophagy activated via the AMPK pathway.
Gasdermin D Protects Mouse Podocytes Against High-Glucose-Induced Inflammation and Apoptosis via the C-Jun N-Terminal Kinase (JNK) Pathway.
Plumbagin, a Biomolecule with (Anti)Osteoclastic Properties.
Expression of Talin-1 in endometriosis and its possible role in pathogenesis.
lncRNA GCAT1 is involved in premature ovarian insufficiency by regulating p27 translation in GCs via competitive binding to PTBP1.
Combining combretastatin A4 phosphate with ginsenoside Rd synergistically inhibited hepatocellular carcinoma by reducing HIF-1α via PI3K/AKT/mTOR signalling pathway.
PUMA facilitates EMI1-promoted cytoplasmic Rad51 ubiquitination and inhibits DNA repair in stem and progenitor cells.
MYC promotes cancer progression by modulating m(6) A modifications to suppress target gene translation.
The CREB/KMT5A complex regulates PTP1B to modulate high glucose-induced endothelial inflammatory factor levels in diabetic nephropathy.
Profiling PRMT methylome reveals roles of hnRNPA1 arginine methylation in RNA splicing and cell growth.
Angiomotin Counteracts the Negative Regulatory Effect of Host WWOX on Viral PPxY-Mediated Egress.
Hispidulin inhibits proliferation, migration, and invasion by promoting autophagy via regulation of PPARγ activation in prostate cancer cells and xenograft models.
Inhibition of lipogenesis and induction of apoptosis by valproic acid in prostate cancer cells via the C/EBPα/SREBP-1 pathway.
Effects of transforming growth factor-β1 on odontoblastic differentiation in dental papilla cells is determined by IPO7 expression level.
hPER3 promotes adipogenesis via hHSP90AA1-mediated inhibition of Notch1 pathway.
Identifying SLC27A5 as a potential prognostic marker of hepatocellular carcinoma by weighted gene co-expression network analysis and in vitro assays.
PEG-GO@XN nanocomposite suppresses breast cancer metastasis via inhibition of mitochondrial oxidative phosphorylation and blockade of epithelial-to-mesenchymal transition.
PCGF3 promotes the proliferation and migration of non-small cell lung cancer cells via the PI3K/AKT signaling pathway.
The Effect of Hispidulin, a Flavonoid from Salvia plebeia, on Human Nasopharyngeal Carcinoma CNE-2Z Cell Proliferation, Migration, Invasion, and Apoptosis.
Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.
Gastrodin ameliorates learning and memory impairment in rats with vascular dementia by promoting autophagy flux via inhibition of the Ca(2+)/CaMKII signal pathway.
Cytotoxicity mechanisms of plumbagin in drug-resistant tongue squamous cell carcinoma.
The deubiquitylase USP9X controls ribosomal stalling.
SZB120 Exhibits Immunomodulatory Effects by Targeting eIF2α to Suppress Th17 Cell Differentiation.
Melatonin inhibits vascular endothelial cell pyroptosis by improving mitochondrial function via up-regulation and demethylation of UQCRC1.
A novel peptide promotes human trophoblast proliferation and migration through PI3K/Akt/mTOR signaling pathway.
Ninjinyoeito improves anxiety behavior in neuropeptide Y deficient zebrafish.
Interleukin-24 as a Pulmonary Target Cytokine in Bronchopulmonary Dysplasia.
Promoterless, Nuclease-Free Genome Editing Confers a Growth Advantage for Corrected Hepatocytes in Mice With Methylmalonic Acidemia.
NCOA4-mediated ferritinophagy promoted inflammatory responses in periodontitis.
Sodium sulfite causes gastric mucosal cell death by inducing oxidative stress.
Golgi phosphoprotein 3 promotes the proliferation of gallbladder carcinoma cells via regulation of the NLRP3 inflammasome.
FMR1/circCHAF1A/miR-211-5p/HOXC8 feedback loop regulates proliferation and tumorigenesis via MDM2-dependent p53 signaling in GSCs.
SMAR1 attenuates the stemness of osteosarcoma cells via through suppressing ABCG2 transcriptional activity.
Small Interfering RNA Targeting DMP1 Protects Mice Against Blood-Brain Barrier Disruption and Brain Injury After Intracerebral Hemorrhage.
Cellular microRNAs influence replication of H3N2 canine influenza virus in infected cells.
Sparstolonin B exerts beneficial effects on prostate cancer by acting on the reactive oxygen species-mediated PI3K/AKT pathway.
Fructose-1,6-bisphosphatase aggravates oxidative stress-induced apoptosis in asthma by suppressing the Nrf2 pathway.
Phgdh serves a protective role in Il‑1β induced chondrocyte inflammation and oxidative‑stress damage.
Exploration of the hepatoprotective effect and mechanism of magnesium isoglycyrrhizinate in mice with arsenic trioxide‑induced acute liver injury.
Resveratrol sensitizes A549 cells to irradiation damage via suppression of store-operated calcium entry with Orai1 and STIM1 downregulation.
Differential expression of protein disulfide isomerase (PDI) in regulating endometrial receptivity in humans.
miR-29a-3p-dependent COL3A1 and COL5A1 expression reduction assists sulforaphane to inhibit gastric cancer progression.
RRx-001 ameliorates inflammatory diseases by acting as a potent covalent NLRP3 inhibitor.
Signal-regulatory protein alpha is an anti-viral entry factor targeting viruses using endocytic pathways.
SNX-3 mediates retromer-independent tubular endosomal recycling by opposing EEA-1-facilitated trafficking.
Paricalcitol inhibits oxidative stress-induced cell senescence of the bile duct epithelium dependent on modulating Sirt1 pathway in cholestatic mice.
Natural molecule Munronoid I attenuates LPS-induced acute lung injury by promoting the K48-linked ubiquitination and degradation of TAK1.
Tumor cell membrane-based peptide delivery system targeting the tumor microenvironment for cancer immunotherapy and diagnosis.
Long non-coding RNA muskelin 1 antisense RNA (MKLN1-AS) is a potential diagnostic and prognostic biomarker and therapeutic target for hepatocellular carcinoma.
Upregulation of ZHX2 predicts poor prognosis and is correlated with immune infiltration in gastric cancer.
Effect of SOCS3 on apoptosis of human trophoblasts via adjustment of the JAK2/STAT3 signaling pathway in preterm birth.
CDK5 positively regulates Notch1 signaling in pancreatic cancer cells by phosphorylation.
PBRM1 Cooperates with YTHDF2 to Control HIF-1α Protein Translation.
Multilevel regulation of Wnt signaling by Zic2 in colon cancer due to mutation of β-catenin.
The combination of CUDC-907 and gilteritinib shows promising in vitro and in vivo antileukemic activity against FLT3-ITD AML.
Hypericin-mediated photodynamic therapy inhibits growth of colorectal cancer cells via inducing S phase cell cycle arrest and apoptosis.
Cisplatin remodels the tumor immune microenvironment via the transcription factor EB in ovarian cancer.
The benzoate plant metabolite ethyl gallate prevents cellular- and vascular-lipid accumulation in experimental models of atherosclerosis.
Alisol A 24-acetate protects against brain microvascular endothelial cells injury through inhibiting miR-92a-3p/tight junctions axis.
Formin-like protein 2 promotes cell proliferation by a p27-related mechanism in human breast cancer cells.
Purification, characterization and anti-atherosclerotic effects of the polysaccharides from the fruiting body of Cordyceps militaris.
Self-stabilizing regulation of deubiquitinating enzymes in an enzymatic activity-dependent manner.
Breast tumor stiffness instructs bone metastasis via maintenance of mechanical conditioning.
Neu1 deficiency induces abnormal emotional behavior in zebrafish.
Thymosin β4 reverses phenotypic polarization of glial cells and cognitive impairment via negative regulation of NF-κB signaling axis in APP/PS1 mice.
The Anti-Tumor Effect and Underlying Apoptotic Mechanism of Ginsenoside Rk1 and Rg5 in Human Liver Cancer Cells.
DUSP1 overexpression attenuates renal tubular mitochondrial dysfunction by restoring Parkin-mediated mitophagy in diabetic nephropathy.
LncRNA CARMN overexpression promotes prognosis and chemosensitivity of triple negative breast cancer via acting as miR143-3p host gene and inhibiting DNA replication.
Binding of Benzo[a]pyrene Alters the Bioreactivity of Fine Biochar Particles toward Macrophages Leading to Deregulated Macrophagic Defense and Autophagy.
LINC00842 inactivates transcription co-regulator PGC-1α to promote pancreatic cancer malignancy through metabolic remodelling.
LINC_00355 promotes gastric cancer progression by upregulating PHF19 expression through sponging miR-15a-5p.
Colorectal cancer cells utilize autophagy to maintain mitochondrial metabolism for cell proliferation under nutrient stress.
Isorhamnetin Promotes Estrogen Biosynthesis and Proliferation in Porcine Granulosa Cells via the PI3K/Akt Signaling Pathway.
Protective effect of scorpion venom heat-resistant synthetic peptide against PM(2.5)-induced microglial polarization via TLR4-mediated autophagy activating PI3K/AKT/NF-κB signaling pathway.
HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron.
Aerobic Exercise Improves Mitochondrial Function in Sarcopenia Mice Through Sestrin2 in an AMPKα2-Dependent Manner.
The engineered expression of secreted HSPB5-Fc in CHO cells exhibits cytoprotection in vitro.
Protective effects of 4-octyl itaconate against inflammatory response in angiotensin II-induced oxidative stress in human primary retinal pigment epithelium.
Protective Effects of Bone Marrow Mesenchymal Stem Cells (BMMSCS) Combined with Normothermic Machine Perfusion on Liver Grafts Donated After Circulatory Death via Reducing the Ferroptosis of Hepatocytes.
Central nervous system-targeted adeno-associated virus gene therapy in methylmalonic acidemia.
LncRNA CTD-2528L19.6 prevents the progression of IPF by alleviating fibroblast activation.
Resveratrol and its derivative pterostilbene ameliorate intestine injury in intrauterine growth-retarded weanling piglets by modulating redox status and gut microbiota.
Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance.
Hyaluronic acid/polyethyleneimine nanoparticles loaded with copper ion and disulfiram for esophageal cancer.
Galectin-9 Targets NLRP3 for Autophagic Degradation to Limit Inflammation.
Butyrate enhances CPT1A activity to promote fatty acid oxidation and iTreg differentiation.
25-Hydroxycholesterol mitigates hepatic ischemia reperfusion injury via mediating mitophagy.
Targeting TSP-1 decreased periodontitis by attenuating extracellular matrix degradation and alveolar bone destruction.
Pirfenidone mediates cigarette smoke extract induced inflammation and oxidative stress in vitro and in vivo.
A neutral polysaccharide from Ophiocordyceps lanpingensis restrains cisplatin-induced nephrotoxicity.
YAP/TEAD4-induced KIF4A contributes to the progression and worse prognosis of esophageal squamous cell carcinoma.
Thioredoxin-1 Rescues MPP(+)/MPTP-Induced Ferroptosis by Increasing Glutathione Peroxidase 4.
miR-671-5p Attenuates Neuroinflammation via Suppressing NF-κB Expression in an Acute Ischemic Stroke Model.
DHCR24 Knockdown Lead to Hyperphosphorylation of Tau at Thr181, Thr231, Ser262, Ser396, and Ser422 Sites by Membrane Lipid-Raft Dependent PP2A Signaling in SH-SY5Y Cells.
Hawthorn polyphenols, D-chiro-inositol, and epigallocatechin gallate exert a synergistic hypoglycemic effect.
EZH2 regulates expression of FOXC1 by mediating H3K27me3 in breast cancers.
The role of the HIF-1α/ALYREF/PKM2 axis in glycolysis and tumorigenesis of bladder cancer.
Sestrin2 protects against traumatic brain injury by reinforcing the activation of Nrf2 signaling.
Targeted radioimmunotherapy with the iodine-131-labeled caerin 1.1 peptide for human anaplastic thyroid cancer in nude mice.
Hepcidin sequesters iron to sustain nucleotide metabolism and mitochondrial function in colorectal cancer epithelial cells.
TCDD induced lipid accumulation by impairment of autophagic flux in THP-1 macrophages.
NT5DC2 promotes leiomyosarcoma tumour cell growth via stabilizing unpalmitoylated TEAD4 and generating a positive feedback loop.
Comparison of multi-walled carbon nanotubes and halloysite nanotubes on lipid profiles in human umbilical vein endothelial cells.
TLR2 senses the SARS-CoV-2 envelope protein to produce inflammatory cytokines.
Effect of the interference with DRP1 expression on the biological characteristics of glioma stem cells.
A conserved ubiquitin- and ESCRT-dependent pathway internalizes human lysosomal membrane proteins for degradation.
C1orf61 promotes hepatocellular carcinoma metastasis and increases the therapeutic response to sorafenib.
Visfatin regulates Pg LPS-induced proinflammatory/prodegradative effects in healthy and inflammatory periodontal cells partially via NF-κB pathway.
Ets-2 deletion in myeloid cells attenuates IL-1α-mediated inflammatory disease caused by a Ptpn6 point mutation.
Mycobacterium tuberculosis inhibits the NLRP3 inflammasome activation via its phosphokinase PknF.
DENV NS1 and MMP-9 cooperate to induce vascular leakage by altering endothelial cell adhesion and tight junction.
Chemical conjugation of FITC to track silica nanoparticles in vivo and in vitro: An emerging method to assess the reproductive toxicity of industrial nanomaterials.
Andrographolide Attenuates Gut-Brain-Axis Associated Pathology in Gulf War Illness by Modulating Bacteriome-Virome Associated Inflammation and Microglia-Neuron Proinflammatory Crosstalk.
ets1 associates with KMT5A to participate in high glucose-mediated EndMT via upregulation of PFN2 expression in diabetic nephropathy.
Inhibition of xCT suppresses the efficacy of anti-PD-1/L1 melanoma treatment through exosomal PD-L1-induced macrophage M2 polarization.
Baicalein Delays H(2)O(2)-Induced Astrocytic Senescence through Inhibition of Senescence-Associated Secretory Phenotype (SASP), Suppression of JAK2/STAT1/NF-κB Pathway, and Regulation of Leucine Metabolism.
Piperlongumine inhibits migration and proliferation of castration-resistant prostate cancer cells via triggering persistent DNA damage.
Baicalein inhibits RLS3-induced ferroptosis in melanocytes.
Melatonin alleviates Ochratoxin A-induced liver inflammation involved intestinal microbiota homeostasis and microbiota-independent manner.
mPEG(2k)-PCL(x) Polymeric Micelles Influence Pharmacokinetics and Hypoglycemic Efficacy of Metformin through Inhibition of Organic Cation Transporters in Rats.
The intrinsic role and mechanism of tumor expressed-CD38 on lung adenocarcinoma progression.
Probiotic-fermented black tartary buckwheat alleviates hyperlipidemia and gut microbiota dysbiosis in rats fed with a high-fat diet.
L-Theanine regulates glutamine metabolism and immune function by binding to cannabinoid receptor 1.
NR1D1 suppressed the growth of ovarian cancer by abrogating the JAK/STAT3 signaling pathway.
Anti-anemia drug FG4592 retards the AKI-to-CKD transition by improving vascular regeneration and antioxidative capability.
Glycoursodeoxycholic acid ameliorates diet-induced metabolic disorders with inhibiting endoplasmic reticulum stress.
Subregion-Specific Regulation of Dopamine D1 Receptor Signaling in the Striatum: Implication for L-DOPA-Induced Dyskinesia.
Growth Hormone Receptor (GHR) 6Ω Pseudoexon Activation: a Novel Cause of Severe Growth Hormone Insensitivity.
HELLS serves as a poor prognostic biomarker and its downregulation reserves the malignant phenotype in pancreatic cancer.
Serum exosomes from young rats improve the reduced osteogenic differentiation of BMSCs in aged rats with osteoporosis after fatigue loading in vivo.
Nuclear iASPP determines cell fate by selectively inhibiting either p53 or NF-κB.
Integrated analysis of m(6)A mRNA methylation in rats with monocrotaline-induced pulmonary arterial hypertension.
Effects of Loblolly Pine Biochar and Wood Vinegar on Poultry Litter Nutrients and Microbial Abundance.
Phenethylamine in chlorella alleviates high-fat diet-induced mouse liver damage by regulating generation of methylglyoxal.
Hypoxic preconditioning rejuvenates mesenchymal stem cells and enhances neuroprotection following intracerebral hemorrhage via the miR-326-mediated autophagy.
VALD-3, a Schiff base ligand synthesized from o-vanillin derivatives, induces cell cycle arrest and apoptosis in breast cancer cells by inhibiting the Wnt/β-catenin pathway.
Lactate secreted by PKM2 upregulation promotes Galectin-9-mediated immunosuppression via inhibiting NF-κB pathway in HNSCC.
Spodoptera frugiperda mRNA export factor interacts with and mediates the nuclear import of Autographa californica multiple nucleopolyhedrovirus ORF34 (Ac34).
Establishment of a specific in vivo Cu(Ⅰ) reporting system based on metallothionein screening.
Potential effect of EGCG on the anti-tumor efficacy of metformin in melanoma cells.
Decreased expression of the clock gene Bmal1 is involved in the pathogenesis of temporal lobe epilepsy.
p53 deficiency induces MTHFD2 transcription to promote cell proliferation and restrain DNA damage.
Cyclophilin A Inhibits Human Respiratory Syncytial Virus (RSV) Replication by Binding to RSV-N through Its PPIase Activity.
Stimuli-Responsive and Highly Penetrable Nanoparticles as a Multifunctional Nanoplatform for Boosting Nonsmall Cell Lung Cancer siRNA Therapy.
Activation of Adenosine A(1) Receptor in Ischemic Stroke: Neuroprotection by Tetrahydroxy Stilbene Glycoside as an Agonist.
The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability.
Evaluating the protective effects of individual or combined ginsenoside compound K and the downregulation of soluble epoxide hydrolase expression against sodium valproate-induced liver cell damage.
MicroRNA-363-3p promotes apoptosis in response to cadmium-induced renal injury by down-regulating phosphoinositide 3-kinase expression.
p55PIK deficiency and its NH(2)-terminal derivative inhibit inflammation and emphysema in COPD mouse model.
Novel functional variants in the Notch pathway and survival of Chinese colorectal cancer.
Alterations of GABA B receptors in the APP/PS1 mouse model of Alzheimer's disease.
Identification and validation of L Antigen Family Member 3 as an immune-related biomarker associated with the progression of papillary thyroid cancer.
Postnatal overfeeding induces hepatic microRNA-221 expression and impairs the PI3K/AKT pathway in adult male rats.
Uncaria rhynchophylla ameliorates unpredictable chronic mild stress-induced depression in mice via activating 5-HT(1A) receptor: Insights from transcriptomics.
Regulation of branched-chain amino acid metabolism by hypoxia-inducible factor in glioblastoma.
miR-937-5p targets SOX17 to modulate breast cancer cell cycle and cell proliferation through the Wnt signaling pathway.
Isoorientin exerts a urate-lowering effect through inhibition of xanthine oxidase and regulation of the TLR4-NLRP3 inflammasome signaling pathway.
Layer-specific strain for assessing the effect of naringin on systolic myocardial dysfunction induced by sepsis and its underlying mechanisms.
Esomeprazole overcomes paclitaxel-resistance and enhances anticancer effects of paclitaxel by inducing autophagy in A549/Taxol cells.
Topotecan induces hepatocellular injury via ASCT2 mediated oxidative stress.
Small extracellular vesicles containing miR-30a-3p attenuate the migration and invasion of hepatocellular carcinoma by targeting SNAP23 gene.
FBW7-NRA41-SCD1 axis synchronously regulates apoptosis and ferroptosis in pancreatic cancer cells.
Senolytic therapy ameliorates renal fibrosis postacute kidney injury by alleviating renal senescence.
Neuropathy-associated histidyl-tRNA synthetase variants attenuate protein synthesis in vitro and disrupt axon outgrowth in developing zebrafish.
Arsenic exposure increased expression of HOTAIR and LincRNA-p21 in vivo and vitro.
CircRNA-vgll3 promotes osteogenic differentiation of adipose-derived mesenchymal stem cells via modulating miRNA-dependent integrin α5 expression.
SNHG1 represses the anti-cancer roles of baicalein in cervical cancer through regulating miR-3127-5p/FZD4/Wnt/β-catenin signaling.
Endogenous promoter-driven sgRNA for monitoring the expression of low-abundance transcripts and lncRNAs.
Protection against Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice by Neferine, A Natural Product from Nelumbo nucifera Gaertn.
Quantitative proteomics reveals stage-specific protein regulation of triple negative breast cancer.
Loss of WD2 subdomain of Apaf-1 forms an apoptosome structure which blocks activation of caspase-3 and caspase-9.
Characteristics of inflammation process in monocrotaline-induced pulmonary arterial hypertension in rats.
Neuroprotective effects of kukoamine A on 6-OHDA-induced Parkinson's model through apoptosis and iron accumulation inhibition.
Improved BMP2-CPC-stimulated osteogenesis in vitro and in vivo via modulation of macrophage polarization.
Hyperglycemia-reduced NAD(+) biosynthesis impairs corneal epithelial wound healing in diabetic mice.
MiR-362 suppresses cervical cancer progression via directly targeting BAP31 and activating TGFβ/Smad pathway.
Identification of an N6-methyladenosine-mediated positive feedback loop that promotes Epstein-Barr virus infection.
Androgen receptor splicing variant 7 (ARV7) inhibits docetaxel sensitivity by inactivating the spindle assembly checkpoint.
The ATPase ATP6V1A facilitates rabies virus replication by promoting virion uncoating and interacting with the viral matrix protein.
Protective Effect of Retrograde Reperfusion Against Hepatic Autophagy Impairment in Rat Liver Transplantation.
Overexpression of ICAT Inhibits the Progression of Colorectal Cancer by Binding with β-Catenin in the Cytoplasm.
The EGFR-HSF1 axis accelerates the tumorigenesis of pancreatic cancer.
Identification of the atypical cadherin FAT1 as a novel glypican-3 interacting protein in liver cancer cells.
Cell surface GRP78 regulates BACE2 via lysosome-dependent manner to maintain mesenchymal phenotype of glioma stem cells.
Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes.
β-Conglycinin induces the formation of neutrophil extracellular traps dependent on NADPH oxidase-derived ROS, PAD4, ERK1/2 and p38 signaling pathways in mice.
Yangonin inhibits ethanol-induced hepatocyte senescence via miR-194/FXR axis.
Progranulin induces immune escape in breast cancer via up-regulating PD-L1 expression on tumor-associated macrophages (TAMs) and promoting CD8(+) T cell exclusion.
NEO100 enables brain delivery of blood‒brain barrier impermeable therapeutics.
Effect of Pregnane X Receptor on CYP3A29 Expression in Porcine Alveolar Macrophages during Mycoplasma hyopneumoniae Infection.
Effects of different concentrations of coated nano zinc oxide material on fecal bacterial composition and intestinal barrier in weaned piglets.
ADAM15 Participates in Tick-Borne Encephalitis Virus Replication.
Angiogenesis is promoted by exosomal DPP4 derived from 5-fluorouracil-resistant colon cancer cells.
Absolute configuration of tetrandrine and isotetrandrine influences their anti-proliferation effects in human T cells via different regulation of NF-κB.
Poly(lactide-co-glycolide) Nanoparticles Mediate Sustained Gene Silencing and Improved Biocompatibility of siRNA Delivery Systems in Mouse Lungs after Pulmonary Administration.
Arsenite induce neurotoxicity of common carp: Involvement of blood brain barrier, apoptosis and autophagy, and subsequently relieved by zinc (Ⅱ) supplementation.
MicroRNA-193a-5p Regulates the Synthesis of Polyunsaturated Fatty Acids by Targeting Fatty Acid Desaturase 1 (FADS1) in Bovine Mammary Epithelial Cells.
Circular RNA circRUNX1 promotes papillary thyroid cancer progression and metastasis by sponging MiR-296-3p and regulating DDHD2 expression.
Diosmetin Ameliorates Nonalcoholic Steatohepatitis through Modulating Lipogenesis and Inflammatory Response in a STAT1/CXCL10-Dependent Manner.
Perampanel Stimulates Mitochondrial Biogenesis in Neuronal Cells through Activation of the SIRT1/PGC-1α Signaling Pathway.
Downregulation of metabotropic glutamate receptor 5 alleviates central sensitization by activating autophagy via inhibiting mTOR pathway in a rat model of chronic migraine.
Mutations in GDAP1 Influence Structure and Function of the Trans-Golgi Network.
Synergism of HPV and MNNG repress miR-218 promoting Het-1A cell malignant transformation by targeting GAB2.
Hypoxic conditioned promotes the proliferation of human olfactory mucosa mesenchymal stem cells and relevant lncRNA and mRNA analysis.
Microcystin-leucine arginine induced the apoptosis of GnRH neurons by activating the endoplasmic reticulum stress resulting in a decrease of serum testosterone level in mice.
Zinc offers splenic protection through suppressing PERK/IRE1-driven apoptosis pathway in common carp (Cyprinus carpio) under arsenic stress.
Curcumin ameliorates mercuric chloride-induced liver injury via modulating cytochrome P450 signaling and Nrf2/HO-1 pathway.
Upregulation of silent information regulator 1 alleviates mitochondrial dysfunction in the trigeminal nucleus caudalis in a rat model of chronic migraine.
iASPP protects the heart from ischemia injury by inhibiting p53 expression and cardiomyocyte apoptosis.
Salvia miltiorrhiza stems and leaves total phenolic acids combination with tanshinone protect against DSS-induced ulcerative colitis through inhibiting TLR4/PI3K/AKT/mTOR signaling pathway in mice.
Aptamer-based CRISPR/Cas12a assay for the ultrasensitive detection of extracellular vesicle proteins.
An identified PfHMGB1 promotes microcystin-LR-induced liver injury of yellow catfish (Pelteobagrus fulvidraco).
The impact of SAMHD1 expression and mutation status in mantle cell lymphoma: An analysis of the MCL Younger and Elderly trial.
Role of Slit2 upregulation in recurrent miscarriage through regulation of stromal decidualization.
mTORC1-mediated amino acid signaling is critical for cell fate determination under transplant-induced stress.
Mutation analysis of MFSD8 in an amyotrophic lateral sclerosis cohort from mainland China.
lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.
The miR-145-5p/CD36 pathway mediates PCB2-induced apoptosis in MCF-7 cells.
Hypoxia-induced PLOD1 overexpression contributes to the malignant phenotype of glioblastoma via NF-κB signaling.
Activation of the G Protein-Coupled Estrogen Receptor Prevented the Development of Acute Colitis by Protecting the Crypt Cell.
TAR DNA-Binding Protein 43 is Cleaved by the Protease 3C of Enterovirus A71.
Enhancer II-targeted dsRNA decreases GDNF expression via histone H3K9 trimethylation to inhibit glioblastoma progression.
Upregulated Nmnat2 causes neuronal death and increases seizure susceptibility in temporal lobe epilepsy.
Piezo2 channel in nodose ganglia neurons is essential in controlling hypertension in a pathway regulated directly by Nedd4-2.
Effect of Babao Dan on angiogenesis of gastric cancer in vitro by regulating VEGFA/VEGFR2 signaling pathway.
Triptolide inhibits epithelial-mesenchymal transition phenotype through the p70S6k/GSK3/β-catenin signaling pathway in taxol-resistant human lung adenocarcinoma.
Tregs facilitate obesity and insulin resistance via a Blimp-1/IL-10 axis.
NOGOB receptor-mediated RAS signaling pathway is a target for suppressing proliferating hemangioma.
Fork head box M1 regulates vascular endothelial growth factor-A expression to promote the angiogenesis and tumor cell growth of gallbladder cancer.
Hypoxic pancreatic stellate cell-derived exosomal mirnas promote proliferation and invasion of pancreatic cancer through the PTEN/AKT pathway.
Human drug efflux transporter ABCC5 confers acquired resistance to pemetrexed in breast cancer.
Exosomes in ovarian cancer ascites promote epithelial-mesenchymal transition of ovarian cancer cells by delivery of miR-6780b-5p.
Correction: Injectable postoperative enzyme-responsive hydrogels for reversing temozolomide resistance and reducing local recurrence after glioma operation.
Impaired Intestinal Akkermansia muciniphila and Aryl Hydrocarbon Receptor Ligands Contribute to Nonalcoholic Fatty Liver Disease in Mice.
Comparison of content-toxicity-activity of six ingenane-type diterpenoids between Euphorbia kansui before and after stir-fried with vinegar by using UFLC-MS/MS, zebrafish embryos and HT-29 cells.
Small extracellular vesicle-mediated Hsp70 intercellular delivery enhances breast cancer adriamycin resistance.
Differential mitochondrial proteomic analysis of A549 cells infected with avian influenza virus subtypes H5 and H9.
Polyamine Analog Diethylnorspermidine Restricts Coxsackievirus B3 and Is Overcome by 2A Protease Mutation In Vitro.
Down-regulation of A(3)AR signaling by IL-6-induced GRK2 activation contributes to Th17 cell differentiation.
Circ_0119872 promotes uveal melanoma development by regulating the miR-622/G3BP1 axis and downstream signalling pathways.
The long noncoding RNA KTN1-AS1 promotes bladder cancer tumorigenesis via KTN1 cis-activation and the consequent initiation of Rho GTPase-mediated signaling.
Protective role of serpina3c as a novel thrombin inhibitor against atherosclerosis in mice.
QiShenYiQi pill activates autophagy to attenuate reactive myocardial fibrosis via the PI3K/AKT/mTOR pathway.
Diosgenin alleviates hypercholesterolemia via SRB1/CES-1/CYP7A1/FXR pathway in high-fat diet-fed rats.
A novel tonicity-responsive microRNA miR-23a-5p modulates renal cell survival under osmotic stress through targeting heat shock protein 70 HSPA1B.
NF-κB pathway play a role in SCD1 deficiency-induced ceramide de novo synthesis.
Vascular endothelial cell-secreted exosomes facilitate osteoarthritis pathogenesis by promoting chondrocyte apoptosis.
Red ginseng has stronger anti-aging effects compared to ginseng possibly due to its regulation of oxidative stress and the gut microbiota.
Gastrodin exerts protective effects in reactive TNC1 astrocytes via regulation of the Notch signaling pathway.
Phosphorylated nuclear factor erythroid 2-related factor 2 promotes the secretion of C-C motif chemokine ligand 2 and the recruitment of M2 macrophages.
IL-27 signalling promotes adipocyte thermogenesis and energy expenditure.
Hypoxia-inducible factor-1α promotes proliferation of airway smooth muscle cells through miRNA-103-mediated signaling pathway under hypoxia.
SIRT2 tyrosine nitration by peroxynitrite in response to renal ischemia/reperfusion injury.
CoCrMo-Nanoparticles induced peri-implant osteolysis by promoting osteoblast ferroptosis via regulating Nrf2-ARE signalling pathway.
Identification of autophagic target RAB13 with small-molecule inhibitor in low-grade glioma via integrated multi-omics approaches coupled with virtual screening of traditional Chinese medicine databases.
Semaglutide attenuates seizure severity and ameliorates cognitive dysfunction by blocking the NLR family pyrin domain containing 3 inflammasome in pentylenetetrazole‑kindled mice.
Endoplasmic reticulum stress pathway mediates T-2 toxin-induced chondrocyte apoptosis.
FOXO1 inhibits prostate cancer cell proliferation via suppressing E2F1 activated NPRL2 expression.
3-Hydroxybenzaldehyde and 4-Hydroxybenzaldehyde enhance survival of mouse astrocytes treated with Angiostrongylus cantonensis young adults excretory/secretory products.
GLO 1 and PKCλ Regulate ALDH1-positive Breast Cancer Stem Cell Survival.
The transcribed ultraconserved element uc.51 promotes the proliferation and metastasis of breast cancer by stabilizing NONO.
ubtor Mutation Causes Motor Hyperactivity by Activating mTOR Signaling in Zebrafish.
Stigmasterol inhibits the progression of lung cancer by regulating retinoic acid-related orphan receptor C.
The flavonoid procyanidin C1 has senotherapeutic activity and increases lifespan in mice.
Caspase-6 promotes activation of the caspase-11-NLRP3 inflammasome during gram-negative bacterial infections.
MEHP induces pyroptosis and autophagy alternation by cathepsin B activation in INS-1 cells.
A bivalent cyclic RGD-siRNA conjugate enhances the antitumor effect of apatinib via co-inhibiting VEGFR2 in non-small cell lung cancer xenografts.
Exosomal ANXA2 derived from ovarian cancer cells regulates epithelial-mesenchymal plasticity of human peritoneal mesothelial cells.
FPR2 serves a role in recurrent spontaneous abortion by regulating trophoblast function via the PI3K/AKT signaling pathway.
Knockdown of TRIM9 attenuates irinotecan‑induced intestinal mucositis in IEC‑6 cells by regulating DUSP6 expression via the P38 pathway.
Suppression of ER-stress induction of GRP78 as an anti-neoplastic mechanism of the cardiac glycoside Lanatoside C in pancreatic cancer: Lanatoside C suppresses GRP78 stress induction.
Danshensu derivative ADTM ameliorates CCl(4)‑induced acute liver injury in mice through inhibiting oxidative stress and apoptosis.
Mel1b and Mel1c melatonin receptors mediate green light-induced secretion of growth hormone in chick adenohypophysis cells via the AC/PKA and ERK1/2 signalling pathways.
Arsenic (III) induces oxidative stress and inflammation in the gills of common carp, which is ameliorated by zinc (II).
Knockdown of METTL14 suppresses the malignant progression of non-small cell lung cancer by reducing Twist expression.
CMPK2 accelerates liver ischemia/reperfusion injury via the NLRP3 signaling pathway.
Hsa-miR-335 enhances cell migration and invasion in lung adenocarcinoma through targeting Copine-1.
Antidepressant effect of catalpol on corticosterone-induced depressive-like behavior involves the inhibition of HPA axis hyperactivity, central inflammation and oxidative damage probably via dual regulation of NF-κB and Nrf2.
Small molecule targeting topoisomerase 3β for cancer therapy.
Dihydroartemisinin ameliorates retinal vascular dysfunction in diabetes mellitus via the FASN/Kmal-mTOR/SREBP1 feedback loop.
Viral RNA N6-methyladenosine modification modulates both innate and adaptive immune responses of human respiratory syncytial virus.
DNA damage-inducible transcript 3 restrains osteoclast differentiation and function.
Acupuncture regulates the autophagy of ovarian granulosa cells in polycystic ovarian syndrome ovulation disorder by inhibiting the PI3K/AKT/mTOR pathway through LncMEG3.
Selenoprotein S attenuates high glucose and/or ox-LDL-induced endothelium injury by regulating Akt/mTOR signaling and autophagy.
Shockwave Treatment Enhanced Extracellular Matrix Production in Articular Chondrocytes Through Activation of the ROS/MAPK/Nrf2 Signaling Pathway.
Silencing FYVE, RhoGEF, and PH domain containing 1 (FGD1) suppresses melanoma progression by inhibiting PI3K/AKT signaling pathway.
Role of Rho guanine nucleotide exchange factors in non-small cell lung cancer.
Mechanistic insights into the renoprotective role of curcumin in cisplatin-induced acute kidney injury: network pharmacology analysis and experimental validation.
Human umbilical vein endothelial cells derived-exosomes promote osteosarcoma cell stemness by activating Notch signaling pathway.
A comprehensive genome-wide analysis of long non-coding RNA and mRNA expression profiles of JAK2V617F-positive classical myeloproliferative neoplasms.
Transcription factor 3 (TCF3) combined with histone deacetylase 3 (HDAC3) down-regulates microRNA-101 to promote Burkitt lymphoma cell proliferation and inhibit apoptosis.
Fat mass and obesity-associated protein (FTO) mediates signal transducer and activator of transcription 3 (STAT3)-drived resistance of breast cancer to doxorubicin.
MicroRNA miR-188-5p as a mediator of long non-coding RNA MALAT1 regulates cell proliferation and apoptosis in multiple myeloma.
A virulent Bacillus cereus strain from deep-sea cold seep induces pyroptosis in a manner that involves NLRP3 inflammasome, JNK pathway, and lysosomal rupture.
ATR kinase activity promotes antibody class switch recombination in B cells through cell cycle regulation without suppressing DSB resection and microhomology usage.
A living cell-based fluorescent reporter for high-throughput screening of anti-tumor drugs.
GABA(A) receptor agonist muscimol rescues inhibitory microcircuit defects in the olfactory bulb and improves olfactory function in APP/PS1 transgenic mice.
1β-Hydroxyalantolactone from Inulae Flos alleviated the progression of pulmonary fibrosis via inhibiting JNK/FOXO1/NF-κB pathway.
Dietary hawthorn-leaves flavonoids improves ovarian function and liver lipid metabolism in aged breeder hens.
Mannan-binding lectin deficiency augments hepatic endoplasmic reticulum stress through IP3R-controlled calcium release.
Transcriptomic-based toxicological investigations of graphene oxide with modest cytotoxicity to human umbilical vein endothelial cells: changes of Toll-like receptor signaling pathways.
Acquiring high expression of suilysin enable non-epidemic Streptococccus suis to cause streptococcal toxic shock-like syndrome (STSLS) through NLRP3 inflammasome hyperactivation.
The Mechanism of Mitochondrial Injury in Alpha-1 Antitrypsin Deficiency Mediated Liver Disease.
SARS-CoV-2 ORF3a Induces Incomplete Autophagy via the Unfolded Protein Response.
MiRNA-132/212 regulates tight junction stabilization in blood-brain barrier after stroke.
NLRP3 inflammasome signal pathway involves in Vibrio harveyi-induced inflammatory response in murine peritoneal macrophages in vitro.
HOPX Plays a Critical Role in Antiretroviral Drugs Induced Epigenetic Modification and Cardiac Hypertrophy.
ZNF382 controls mouse neuropathic pain via silencer-based epigenetic inhibition of Cxcl13 in DRG neurons.
Biophysical and biochemical properties of PHGDH revealed by studies on PHGDH inhibitors.
Diacerein attenuates vascular dysfunction by reducing inflammatory response and insulin resistance in type 2 diabetic rats.
Irisin Association with Ki-67, MCM3 and MT-I/II in Squamous Cell Carcinomas of the Larynx.
CD38 activation by monosodium urate crystals contributes to inflammatory responses in human and murine macrophages.
USP30-AS1 contributes to mitochondrial quality control in glioblastoma cells.
Loss of ATF4 leads to functional aging-like attrition of adult hematopoietic stem cells.
Antiplatelet and Antithrombotic Effects of Isaridin E Isolated from the Marine-Derived Fungus via Downregulating the PI3K/Akt Signaling Pathway.
Installation of Pargyline, a LSD1 Inhibitor, in the HDAC Inhibitory Template Culminated in the Identification of a Tractable Antiprostate Cancer Agent.
Heat stress affects fetal brain and intestinal function associated with the alterations of placental barrier in late pregnant mouse.
Interleukin-37 inhibits inflammation activation and disease severity of PM2.5-induced airway hyperresponsiveness.
Cancer-associated fibroblasts promote oral squamous cell carcinoma progression through LOX-mediated matrix stiffness.
Nuclear factor I-C disrupts cellular homeostasis between autophagy and apoptosis via miR-200b-Ambra1 in neural tube defects.
p66α Suppresses Breast Cancer Cell Growth and Migration by Acting as Co-Activator of p53.
Nucleosomes enter cells by clathrin- and caveolin-dependent endocytosis.
Evaluating the Effect of Lenvatinib on Sorafenib-Resistant Hepatocellular Carcinoma Cells.
A distributed residue network permits conformational binding specificity in a conserved family of actin remodelers.
MIF promotes neurodegeneration and cell death via its nuclease activity following traumatic brain injury.
TCF4 and HuR mediated-METTL14 suppresses dissemination of colorectal cancer via N6-methyladenosine-dependent silencing of ARRDC4.
Probiotic Bacillus cereus Alleviates Dextran Sulfate Sodium-Induced Colitis in Mice through Improvement of the Intestinal Barrier Function, Anti-Inflammation, and Gut Microbiota Modulation.
Tangeretin maintains antioxidant activity by reducing CUL3 mediated NRF2 ubiquitination.
ERα promotes transcription of tumor suppressor gene ApoA-I by establishing H3K27ac-enriched chromatin microenvironment in breast cancer cells.
The laminin-binding integrins regulate nuclear factor κB-dependent epithelial cell polarity and inflammation.
Suppressing Alpha-Hemolysin as Potential Target to Screen of Flavonoids to Combat Bacterial Coinfection.
TRPV1 channel mediates NLRP3 inflammasome-dependent neuroinflammation in microglia.
α-Synuclein aggregation in the olfactory bulb induces olfactory deficits by perturbing granule cells and granular-mitral synaptic transmission.
Polysaccharide CM1 from Cordyceps militaris hinders adipocyte differentiation and alleviates hyperlipidemia in LDLR((+/-)) hamsters.
Carnosol alleviates nonalcoholic fatty liver disease by inhibiting mitochondrial dysfunction and apoptosis through targeting of PRDX3.
Involvement of endoplasmic reticulum stress-activated PERK-eIF2α-ATF4 signaling pathway in T-2 toxin-induced apoptosis of porcine renal epithelial cells.
PAX5-activated lncRNA ARRDC1-AS1 accelerates the autophagy and progression of DLBCL through sponging miR-2355-5p to regulate ATG5.
Ketamine enhances novel object recognition memory reconsolidation via the BDNF/TrkB pathway in mice.
Role of the hippo signaling pathway in the extracellular matrix degradation of chondrocytes induced by fluoride exposure.
Cypermethrin triggers YY1-mediated testosterone biosynthesis suppression.
Quercetin reverses chronic unpredictable mild stress-induced depression-like behavior in vivo by involving nuclear factor-E2-related factor 2.
Metformin alleviates hydrogen peroxide-induced inflammation and oxidative stress via inhibiting P2X7R signaling in spinal cord tissue cells neurons.
AKR1C3 decreased CML sensitivity to Imatinib in bone marrow microenvironment via dysregulation of miR-379-5p.
Heat shock protein 90 inhibitor ameliorates pancreatic fibrosis by degradation of transforming growth factor-β receptor.
Microglial Calhm2 regulates neuroinflammation and contributes to Alzheimer's disease pathology.
Rapid generation of maternal mutants via oocyte transgenic expression of CRISPR-Cas9 and sgRNAs in zebrafish.
The intervention of intestinal Wnt/β-catenin pathway alters inflammation and disease severity of CIA.
Milk Polar Lipids Supplementation to Obese Rats During Pregnancy and Lactation Benefited Skeletal Outcomes of Male Offspring.
H. pylori infection induces CXCL8 expression and promotes gastric cancer progress through downregulating KLF4.
Exosomal miR-193b-5p as a regulator of LPS-induced inflammation in dairy cow mammary epithelial cells.
Circadian misalignment promotes vascular smooth muscle cell apoptosis via defective autophagy.
Progranulin promotes osteogenic differentiation of periodontal membrane stem cells in both inflammatory and non-inflammatory conditions.
Lipocalin-2: a role in hepatic gluconeogenesis via AMP-activated protein kinase (AMPK).
Hepatoprotective effects of loach (Misgurnus anguillicaudatus) lyophilized powder on dimethylnitrosamine-induced liver fibrosis in rats.
Chicoric acid attenuates hyperglycemia-induced endothelial dysfunction through AMPK-dependent inhibition of oxidative/nitrative stresses.
W436, a novel SMART derivative, exhibits anti-hepatocarcinoma activity by inducing apoptosis and G2/M cell cycle arrest in vitro and in vivo and induces protective autophagy.
Immunization with recombinant E(rns)-LTB fusion protein elicits protective immune responses against bovine viral diarrhea virus.
Downregulation of SUN2 promotes metastasis of colon cancer by activating BDNF/TrkB signalling by interacting with SIRT1.
Procyanidin B2 alleviates liver injury caused by cold stimulation through Sonic hedgehog signalling and autophagy.
LncRNA MAYA promotes iron overload and hepatocyte senescence through inhibition of YAP in non-alcoholic fatty liver disease.
CircPLCE1 facilitates the malignant progression of colorectal cancer by repressing the SRSF2-dependent PLCE1 pre-RNA splicing.
Fisetin mitigates hepatic ischemia-reperfusion injury by regulating GSK3β/AMPK/NLRP3 inflammasome pathway.
DDIT3/CHOP promotes autophagy in chondrocytes via SIRT1-AKT pathway.
Targeting P2RX1 alleviates renal ischemia/reperfusion injury by preserving mitochondrial dynamics.
MondoA-Thioredoxin-Interacting Protein Axis Maintains Regulatory T-Cell Identity and Function in Colorectal Cancer Microenvironment.
Ferroptosis inducer erastin sensitizes NSCLC cells to celastrol through activation of the ROS-mitochondrial fission-mitophagy axis.
Momordin Ic induces G0/1 phase arrest and apoptosis in colon cancer cells by suppressing SENP1/c-MYC signaling pathway.
The active ingredients and mechanisms of Longchai Jiangxue Formula in treating PV, based on UPLC/Q-TOF-MS/MS, systematic pharmacology, and molecular biology validation.
Systematic investigation of the pharmacological mechanism for renal protection by the leaves of Eucommia ulmoides Oliver using UPLC-Q-TOF/MS combined with network pharmacology analysis.
Grouper TRAF5 exerts negative regulation on antiviral immune response against iridovirus.
CSNK2A1-mediated phosphorylation of HMGA2 modulates cisplatin resistance in cervical cancer.
Lipoxin A4 protects primary spinal cord neurons from Erastin-induced ferroptosis by activating the Akt/Nrf2/HO-1 signaling pathway.
Bone morphogenetic protein-7 inhibits endothelial-to-mesenchymal transition in primary human umbilical vein endothelial cells and mouse model of systemic sclerosis via Akt/mTOR/p70S6K pathway.
Melatonin mediates monochromatic light-induced expression of somatostatin in the hypothalamus and pituitary of chicks.
Suramin attenuates intervertebral disc degeneration by inhibiting NF-κB signalling pathway.
Extract of Cynomorium songaricum ameliorates mitochondrial ultrastructure impairments and dysfunction in two different in vitro models of Alzheimer's disease.
Metformin Is a Pyridoxal-5'-phosphate (PLP)-Competitive Inhibitor of SHMT2.
TRIM28 SUMOylates and stabilizes NLRP3 to facilitate inflammasome activation.
Association of CASC18/miR-20a-3p/TGFB2 ceRNA axis with occult lymph node metastasis in tongue squamous cell carcinoma.
DEAD-box helicase 27 enhances stem cell-like properties with poor prognosis in breast cancer.
METTL3 regulates PM(2.5)-induced cell injury by targeting OSGIN1 in human airway epithelial cells.
Mammalian target of rapamycin signaling pathway is involved in synaptic plasticity of the spinal dorsal horn and neuropathic pain in rats by regulating autophagy.
circBTBD7 Promotes Immature Porcine Sertoli Cell Growth through Modulating miR-24-3p/MAPK7 Axis to Inactivate p38 MAPK Signaling Pathway.
Targeting Amino Acid Metabolic Reprogramming via L-Type Amino Acid Transporter 1 (LAT1) for Endocrine-Resistant Breast Cancer.
The COL-4A1 polypeptide destroy endothelial cells through the TGF-β/PI3K/AKT pathway.
CCT5 interacts with cyclin D1 promoting lung adenocarcinoma cell migration and invasion.
Association of T2285C polymorphism in PARP1 gene coding region with its expression, activity and NSCLC risk along with prognosis.
Glyceraldehyde-3-Phosphate Dehydrogenase Restricted in Cytoplasmic Location by Viral GP5 Facilitates Porcine Reproductive and Respiratory Syndrome Virus Replication via Its Glycolytic Activity.
Hepatoprotective effect of anemoside B4 against sepsis-induced acute liver injury through modulating the mTOR/p70S6K-mediated autophagy.
Ten-eleven translocation 1 mediated-DNA hydroxymethylation is required for myelination and remyelination in the mouse brain.
Circular RNA CircEYA3 induces energy production to promote pancreatic ductal adenocarcinoma progression through the miR-1294/c-Myc axis.
HIF-1α-activated TM4SF1-AS1 promotes the proliferation, migration, and invasion of hepatocellular carcinoma cells by enhancing TM4SF1 expression.
Advanced oxidation protein products impair autophagic flux in macrophage by inducing lysosomal dysfunction via activation of PI3K-Akt-mTOR pathway in Crohn's disease.
MicroRNA-138-1-3p sensitizes sorafenib to hepatocellular carcinoma by targeting PAK5 mediated β-catenin/ABCB1 signaling pathway.
The RNA m6A reader YTHDF2 controls NK cell antitumor and antiviral immunity.
Polysaccharides from Ulva prolifera O.F. Müller inhibit cell proliferation via activating MAPK signaling in A549 and H1650 cells.
Ceruloplasmin correlates with immune infiltration and serves as a prognostic biomarker in breast cancer.
Silibinin Suppresses Tumor Cell-Intrinsic Resistance to Nintedanib and Enhances Its Clinical Activity in Lung Cancer.
Serum DJ-1 Is a Biomarker of Colorectal Cancer and DJ-1 Activates Mitophagy to Promote Colorectal Cancer Progression.
Large-scale and high-resolution mass spectrometry-based proteomics profiling defines molecular subtypes of esophageal cancer for therapeutic targeting.
In vitro assessment of a synergistic combination of gemcitabine and zebularine in pancreatic cancer cells.
Microtubule associated protein 4 (MAP4) phosphorylation reduces cardiac microvascular density through NLRP3-related pyroptosis.
KAT2A-mediated AR translocation into nucleus promotes abiraterone-resistance in castration-resistant prostate cancer.
Metformin attenuates renal tubulointerstitial fibrosis via upgrading autophagy in the early stage of diabetic nephropathy.
Nervous Necrosis Virus Coat Protein Mediates Host Translation Shutoff through Nuclear Translocalization and Degradation of Polyadenylate Binding Protein.
Ophiocordyceps lanpingensis polysaccharides alleviate chronic kidney disease through MAPK/NF-κB pathway.
LncRNA LINC00680 promotes lung adenocarcinoma growth via binding to GATA6 and canceling GATA6-mediated suppression of SOX12 expression.
Empagliflozin, a sodium glucose cotransporter-2 inhibitor, ameliorates peritoneal fibrosis via suppressing TGF-β/Smad signaling.
Ergosterol peroxide exhibits antiviral and immunomodulatory abilities against porcine deltacoronavirus (PDCoV) via suppression of NF-κB and p38/MAPK signaling pathways in vitro.
LncRNA ABCC6P1 promotes proliferation and migration of papillary thyroid cancer cells via Wnt/β-catenin signaling pathway.
Limonin induces apoptosis of HL-60 cells by inhibiting NQO1 activity.
Melatonin Ameliorates Lipopolysaccharide-Induced Microglial Inflammation via Triggering SIRT1/HMGB1 Signaling Axis.
Pooled CRISPR screening identifies m(6)A as a positive regulator of macrophage activation.
Bio-inspired chiral self-assemblies promoted neuronal differentiation of retinal progenitor cells through activation of metabolic pathway.
Perilipin 4 Protein: an Impending Target for Amyotrophic Lateral Sclerosis.
Inhibition of soluble epoxide hydrolase (sEH) protects hippocampal neurons and reduces cognitive decline in type 2 diabetic mice.
Let-7 mediated airway remodelling in chronic obstructive pulmonary disease via the regulation of IL-6.
Expression of lncRNA CCAT2 in children with neuroblastoma and its effect on cancer cell growth.
Induction of NUPR1 and AP‑1 contributes to the carcinogenic potential of nickel.
Anti-thrombotic activity of phenolic acids obtained from Salvia miltiorrhiza f. alba in TNF-α-stimulated endothelial cells via the NF-κB/JNK/p38 MAPK signaling pathway.
miR-182-5p and miR-96-5p Target PIAS1 and Mediate the Negative Feedback Regulatory Loop between PIAS1 and STAT3 in Endometrial Cancer.
CRISPR/Cas9 library screening uncovered methylated PKP2 as a critical driver of lung cancer radioresistance by stabilizing β-catenin.
The orphan nuclear receptor Nurr1 agonist amodiaquine mediates neuroprotective effects in 6-OHDA Parkinson's disease animal model by enhancing the phosphorylation of P38 mitogen-activated kinase but not PI3K/AKT signaling pathway.
Programmed cell death 4 modulates lysosomal function by inhibiting TFEB translation.
ARFGAP1 binds to classical swine fever virus NS5A protein and enhances CSFV replication in PK-15 cells.
MARCH5 restores endothelial cell function against ischaemic/hypoxia injury via Akt/eNOS pathway.
Method used to establish a large animal model of drug-induced acute kidney injury.
Postnatal growth retardation is associated with deteriorated intestinal mucosal barrier function using a porcine model.
[Effect of astragaloside IV on the expression of NOD-like receptor protein 3 inflammasome in neonatal rats with hypoxic-ischemic brain damage].
LncIHAT Is Induced by Hypoxia-Inducible Factor 1 and Promotes Breast Cancer Progression.
Cigarette smoke extract amplifies NADPH oxidase-dependent ROS production to inactivate PTEN by oxidation in BEAS-2B cells.
Low-dose naltrexone plays antineoplastic role in cervical cancer progression through suppressing PI3K/AKT/mTOR pathway.
The S100 calcium-binding protein A11 promotes hepatic steatosis through RAGE-mediated AKT-mTOR signaling.
Resveratrol Attenuates Meningitic Escherichia coli-Mediated Blood-Brain Barrier Disruption.
PolyQ-expanded proteins impair cellular proteostasis of ataxin-3 through sequestering the co-chaperone HSJ1 into aggregates.
N(6)-methyladenosine-binding protein YTHDF1 suppresses EBV replication and promotes EBV RNA decay.
ASIC1 and ASIC3 mediate cellular senescence of human nucleus pulposus mesenchymal stem cells during intervertebral disc degeneration.
EGFR-ERK induced activation of GRHL1 promotes cell cycle progression by up-regulating cell cycle related genes in lung cancer.
miR-190 promotes malignant transformation and progression of human urothelial cells through CDKN1B/p27 inhibition.
Pterostilbene, a Dimethylether Analogue of Resveratrol, Possesses High Potency in the Prevention of Platelet Activation in Humans and the Reduction of Vascular Thrombosis in Mice.
Fludarabine Inhibits Infection of Zika Virus, SFTS Phlebovirus, and Enterovirus A71.
Dynamic evolution of emphysema and airway remodeling in two mouse models of COPD.
Leukemia inhibitory factor regulates Schwann cell proliferation and migration and affects peripheral nerve regeneration.
Circ11103 Interacts with miR-128/PPARGC1A to Regulate Milk Fat Metabolism in Dairy Cows.
H(2)O(2) enhances the anticancer activity of TMPyP4 by ROS-mediated mitochondrial dysfunction and DNA damage.
Buprenorphine alters microglia and astrocytes acutely following diffuse traumatic brain injury.
CK2 Activity Mediates the Aggressive Molecular Signature of Glioblastoma Multiforme by Inducing Nerve/Glial Antigen (NG)2 Expression.
Identification of a mesenchymal-related signature associated with clinical prognosis in glioma.
Btk knockout attenuates the liver inflammation in STZ-induced diabetic mice by suppressing NLRP3 inflammasome activation.
Chemoproteomics-enabled discovery of covalent RNF114-based degraders that mimic natural product function.
Loss of Mitochondrial Protease CLPP Activates Type I IFN Responses through the Mitochondrial DNA-cGAS-STING Signaling Axis.
AKR1B10 negatively regulates autophagy through reducing GAPDH upon glucose starvation in colon cancer.
Kisspeptin-10 Maintains the Activation of the mTOR Signaling Pathway by Inhibiting SIRT6 to Promote the Synthesis of Milk in Bovine Mammary Epithelial Cells.
AIF3 splicing switch triggers neurodegeneration.
An Experimentally Induced Mutation in the UBA Domain of p62 Changes the Sensitivity of Cisplatin by Up-Regulating HK2 Localisation on the Mitochondria and Increasing Mitophagy in A2780 Ovarian Cancer Cells.
Nonsegmented Negative-Sense RNA Viruses Utilize N(6)-Methyladenosine (m(6)A) as a Common Strategy To Evade Host Innate Immunity.
Kaempferol induces ROS-dependent apoptosis in pancreatic cancer cells via TGM2-mediated Akt/mTOR signaling.
Effect of Shuangdan Mingmu capsule, a Chinese herbal formula, on oxidative stress-induced apoptosis of pericytes through PARP/GAPDH pathway.
TET1 may contribute to hypoxia-induced epithelial to mesenchymal transition of endometrial epithelial cells in endometriosis.
Lycopene alleviates oxidative stress via the PI3K/Akt/Nrf2pathway in a cell model of Alzheimer's disease.
Tethering of Telomeres to the Nuclear Envelope Is Mediated by SUN1-MAJIN and Possibly Promoted by SPDYA-CDK2 During Meiosis.
Enterohemorrhagic Escherichia coli Effector Protein EspF Interacts With Host Protein ANXA6 and Triggers Myosin Light Chain Kinase (MLCK)-Dependent Tight Junction Dysregulation.
Safrana l Prevents Prostate Cancer Recurrence by Blocking the Re-activation of Quiescent Cancer Cells via Downregulation of S-Phase Kinase-Associated Protein 2.
miR-7-5p Affects Brain Edema After Intracerebral Hemorrhage and Its Possible Mechanism.
Amnion-Derived Mesenchymal Stem Cell Exosomes-Mediated Autophagy Promotes the Survival of Trophoblasts Under Hypoxia Through mTOR Pathway by the Downregulation of EZH2.
C2C12 Mouse Myoblasts Damage Induced by Oxidative Stress Is Alleviated by the Antioxidant Capacity of the Active Substance Phloretin.
Ferroptosis-Related Gene Signature Predicts Glioma Cell Death and Glioma Patient Progression.
miR-205 Expression Elevated With EDS Treatment and Induced Leydig Cell Apoptosis by Targeting RAP2B via the PI3K/AKT Signaling Pathway.
Ketamine ameliorates hypoxia-induced endothelial injury in human umbilical vein endothelial cells.
Cdk5 Inhibitory Peptide Prevents Loss of Neurons and Alleviates Behavioral Changes in p25 Transgenic Mice.
Maternal Methyl-Donor Micronutrient Supplementation During Pregnancy Promotes Skeletal Muscle Differentiation and Maturity in Newborn and Weaning Pigs.
Potential Role of SLC5A8 Expression in the Etiology of Subacute Ruminal Acidosis.
miR-124-3p Suppresses the Invasiveness and Metastasis of Hepatocarcinoma Cells via Targeting CRKL.
MicroRNA-362-3p Inhibits Migration and Invasion via Targeting BCAP31 in Cervical Cancer.
Metformin effectively treats Tsc1 deletion-caused kidney pathology by upregulating AMPK phosphorylation.
miR-143-3p inhibition promotes neuronal survival in an Alzheimer's disease cell model by targeting neuregulin-1.
Modulation of Wnt/β-catenin signaling in IL-17A-mediated macrophage polarization of RAW264.7 cells.
Antrodia Cinnamomea Attenuates Non-Alcoholic Steatohepatitis by Suppressing NLRP3 Inflammasome Activation In Vitro and In Vivo.
Koumine Alleviates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction in IPEC-J2 Cells by Regulating Nrf2/NF-κB Pathway.
Osthole Improves Cognitive Function of Vascular Dementia Rats: Reducing Aβ Deposition via Inhibition NLRP3 Inflammasome.
Dietary Baicalin Zinc Supplementation Alleviates Oxidative Stress and Enhances Nutrition Absorption in Deoxynivalenol Challenged Pigs.
Heme Oxygenase-1-Mediated Autophagy Protects against Oxidative Damage in Rat Nucleus Pulposus-Derived Mesenchymal Stem Cells.
Environmental Pollutant Benzo[a]pyrene Induces Recurrent Pregnancy Loss through Promoting Apoptosis and Suppressing Migration of Extravillous Trophoblast.
Disease Mutation Study Identifies Critical Residues for Phosphatidylserine Flippase ATP11A.
Rhein Suppresses Neuroinflammation via Multiple Signaling Pathways in LPS-Stimulated BV2 Microglia Cells.
Hydrogen Gas Attenuates Hypoxic-Ischemic Brain Injury via Regulation of the MAPK/HO-1/PGC-1a Pathway in Neonatal Rats.
Human Tissue Kallikrein 1 Improves Erectile Dysfunction of Streptozotocin-Induced Diabetic Rats by Inhibition of Excessive Oxidative Stress and Activation of the PI3K/AKT/eNOS Pathway.
Bergenin Attenuates Hepatic Fibrosis by Regulating Autophagy Mediated by the PPAR-γ/TGF-β Pathway.
Hyperglycemia Induces Endoplasmic Reticulum Stress in Atrial Cardiomyocytes, and Mitofusin-2 Downregulation Prevents Mitochondrial Dysfunction and Subsequent Cell Death.
Mild Hypothermia Attenuates Hepatic Ischemia-Reperfusion Injury through Regulating the JAK2/STAT3-CPT1a-Dependent Fatty Acid β-Oxidation.
Dexmedetomidine Attenuates Neurotoxicity in Developing Rats Induced by Sevoflurane through Upregulating BDNF-TrkB-CREB and Downregulating ProBDNF-P75NRT-RhoA Signaling Pathway.
NLRC3 Delays the Progression of AD in APP/PS1 Mice via Inhibiting PI3K Activation.
Qingjie Fuzheng Granule Inhibited the Migration and Invasion of Colorectal Cancer Cells by Regulating the lncRNA ANRIL/let-7a/TGF-β1/Smad Axis.
The Nrf2/PGC1α Pathway Regulates Antioxidant and Proteasomal Activity to Alter Cisplatin Sensitivity in Ovarian Cancer.
Congrong Shujing Granule-Induced GRP78 Expression Reduced Endoplasmic Reticulum Stress and Neuronal Apoptosis in the Midbrain in a Parkinson's Disease Rat Model.
LncRNA CAR10 Upregulates PDPK1 to Promote Cervical Cancer Development by Sponging miR-125b-5p.
Fasting Induces Hepatocellular Carcinoma Cell Apoptosis by Inhibiting SET8 Expression.
Tyrosine Kinase Receptors Axl and MerTK Mediate the Beneficial Effect of Electroacupuncture in a Cuprizone-Induced Demyelinating Model.
Gubenzhike Recipe Ameliorates Respiratory Mucosal Immunity in Mice with Chronic Obstructive Pulmonary Disease through Upregulation of the γδT Lymphocytes and KGF Levels.
Hypouricemic Effects of Extracts from Urtica hyperborea Jacq. ex Wedd. in Hyperuricemia Mice through XOD, URAT1, and OAT1.
Gentiopicroside Ameliorates Oxidative Stress and Lipid Accumulation through Nuclear Factor Erythroid 2-Related Factor 2 Activation.
Mechanisms of Cong Rong Shu Jing Compound Effects on Endoplasmic Reticulum Stress in a Rat Model of Parkinson's Disease.
N-Butanol Extract of Gastrodia elata Suppresses Inflammatory Responses in Lipopolysaccharide-Stimulated Macrophages and Complete Freund's Adjuvant- (CFA-) Induced Arthritis Rats via Inhibition of MAPK Signaling Pathway.
Effect of Thymoquinone on Acute Kidney Injury Induced by Sepsis in BALB/c Mice.
HuR Affects Proliferation and Apoptosis of Chronic Lymphocytic Leukemia Cells via NF-κB Pathway.
Azelaic Acid Exerts Antileukemia Effects against Acute Myeloid Leukemia by Regulating the Prdxs/ROS Signaling Pathway.
Melatonin Alleviates Neuroinflammation and Metabolic Disorder in DSS-Induced Depression Rats.
Suppression of NLRP3 Inflammasome, Pyroptosis, and Cell Death by NIM811 in Rotenone-Exposed Cells as an in vitro Model of Parkinson's Disease.
MiR-1307-5p targeting TRAF3 upregulates the MAPK/NF-κB pathway and promotes lung adenocarcinoma proliferation.
XIST lost induces ovarian cancer stem cells to acquire taxol resistance via a KMT2C-dependent way.
TET1 promotes fatty acid oxidation and inhibits NAFLD progression by hydroxymethylation of PPARα promoter.
Integrin α1 promotes tumorigenicity and progressive capacity of colorectal cancer.
PFKP is transcriptionally repressed by BRCA1/ZBRK1 and predicts prognosis in breast cancer.
Structure-function analyses of candidate small molecule RPN13 inhibitors with antitumor properties.
Jia-Ji Electro-Acupuncture Improves Locomotor Function With Spinal Cord Injury by Regulation of Autophagy Flux and Inhibition of Necroptosis.
Hydrogen Sulfide Overproduction Is Involved in Acute Ischemic Cerebral Injury Under Hyperhomocysteinemia.
Olfactory Mucosa Mesenchymal Stem Cells Ameliorate Cerebral Ischemic/Reperfusion Injury Through Modulation of UBIAD1 Expression.
Differences in DNA Methylation Reprogramming Underlie the Sexual Dimorphism of Behavioral Disorder Caused by Prenatal Stress in Rats.
iTRAQ-Based Quantitative Proteomic Analysis of Intestines in Murine Polymicrobial Sepsis with Hydrogen Gas Treatment.
Identification of a Novel c-Myc Inhibitor 7594-0037 by Structure-Based Virtual Screening and Investigation of Its Anti-Cancer Effect on Multiple Myeloma.
The Potential Effects of Aliskiren on Atrial Remodeling Induced by Chronic Intermittent Hypoxia in Rats.
Electro-Acupuncture Promotes the Differentiation of Endogenous Neural Stem Cells via Exosomal microRNA 146b After Ischemic Stroke.
Paeoniflorin Ameliorates Chronic Hypoxia/SU5416-Induced Pulmonary Arterial Hypertension by Inhibiting Endothelial-to-Mesenchymal Transition.
The knockdown of the sepiapterin reductase gene suppresses the proliferation of breast cancer by inducing ROS-mediated apoptosis.
Chaetomugilin J Enhances Apoptosis in Human Ovarian Cancer A2780 Cells Induced by Cisplatin Through Inhibiting Pink1/Parkin Mediated Mitophagy.
MicroRNA-623 Inhibits Epithelial-Mesenchymal Transition to Attenuate Glioma Proliferation by Targeting TRIM44.
Excessive Treadmill Training Enhances Brain-Specific MicroRNA-34a in the Mouse Hippocampus.
Chronic Intermittent Hypobaric Hypoxia Restores Hippocampus Function and Rescues Cognitive Impairments in Chronic Epileptic Rats via Wnt/β-catenin Signaling.
β-Elemene Enhances the Chemotherapeutic Effect of 5-Fluorouracil in Triple-Negative Breast Cancer via PI3K/AKT, RAF-MEK-ErK, and NF-κB Signaling Pathways.
Elevated Levels of circRUNX1 in Colorectal Cancer Promote Cell Growth and Metastasis via miR-145-5p/IGF1 Signalling.
Microsatellite Instability-Related ACVR2A Mutations Partially Account for Decreased Lymph Node Metastasis in MSI-H Gastric Cancers.
Long Noncoding RNA NEAT1 Upregulates Survivin and Facilitates Gallbladder Cancer Progression by Sponging microRNA-335.
Alpha1-Antitrypsin in Urinary Extracellular Vesicles: A Potential Biomarker of Diabetic Kidney Disease Prior to Microalbuminuria.
Empagliflozin Protects Against Proximal Renal Tubular Cell Injury Induced by High Glucose via Regulation of Hypoxia-Inducible Factor 1-Alpha.
Simultaneous Inhibition of Ornithine Decarboxylase 1 and Pyruvate Kinase M2 Exerts Synergistic Effects Against Hepatocellular Carcinoma Cells.
MiR-935/HIF1α Feedback Loop Inhibits the Proliferation and Invasiveness of Glioma.
SNHG9 was upregulated in NSCLC and associated with DDP-resistance and poor prognosis of NSCLC patients.
Brequinar inhibits enterovirus replication by targeting biosynthesis pathway of pyrimidines.
A New Rat Model of Chronic Cerebral Hypoperfusion Resulting in Early-Stage Vascular Cognitive Impairment.
Overexpression of IGFBP5 Enhances Radiosensitivity Through PI3K-AKT Pathway in Prostate Cancer.
Long Noncoding RNA LINC00261 Reduces Proliferation and Migration of Breast Cancer Cells via the NME1-EMT Pathway.
Resatorvid Relieves Breast Cancer Complicated with Depression by Inactivating Hippocampal Microglia Through TLR4/NF-κB/NLRP3 Signaling Pathway.
The lncRNA BCYRN1 Functions as an Oncogene in Human Glioma by Downregulating miR-125a-5p in vitro.
Pyruvate dehydrogenase kinase 1 interferes with glucose metabolism reprogramming and mitochondrial quality control to aggravate stress damage in cancer.
Long Noncoding RNA DSCAM-AS1 Facilitates Colorectal Cancer Cell Proliferation and Migration via miR-137/Notch1 Axis.
Arsenic trioxide (ATO) induced degradation of Cyclin D1 sensitized PD-1/PD-L1 checkpoint inhibitor in oral and esophageal squamous cell carcinoma.
Translocator Protein 18 kDa (TSPO) Deficiency Inhibits Microglial Activation and Impairs Mitochondrial Function.
Mitochondrial Iron Overload-Mediated Inhibition of Nrf2-HO-1/GPX4 Assisted ALI-Induced Nephrotoxicity.
Histone Deacetylase SIRT1 Mediates C5b-9-Induced Cell Cycle in Oligodendrocytes.
Oleoylethanolamide Protects Against Acute Liver Injury by Regulating Nrf-2/HO-1 and NLRP3 Pathways in Mice.
A Mechanism of Action Study on Danggui Sini Decoction to Discover Its Therapeutic Effect on Gastric Cancer.
JAK2(V617F) Mutation Promoted IL-6 Production and Glycolysis via Mediating PKM1 Stabilization in Macrophages.
Bu-Shen-Huo-Xue Decoction Ameliorates Diabetic Nephropathy by Inhibiting Rac1/PAK1/p38MAPK Signaling Pathway in High-Fat Diet/Streptozotocin-Induced Diabetic Mice.
miR-222 Suppresses Immature Porcine Sertoli Cell Growth by Targeting the GRB10 Gene Through Inactivating the PI3K/AKT Signaling Pathway.
Bu-Yin-Qian-Zheng Formula Ameliorates MPP(+)-Induced Mitochondrial Dysfunction in Parkinson's Disease via Parkin.
Molecular and Immune Characteristics for Lung Adenocarcinoma Patients With ERLIN2 Overexpression.
microRNA-630 Regulates Underglycosylated IgA1 Production in the Tonsils by Targeting TLR4 in IgA Nephropathy.
Metabolomics Deciphers Potential Targets of Xuefu Zhuyu Decoction Against Traumatic Brain Injury in Rat.
Susceptibility to Hyperglycemia in Rats With Stress-Induced Depressive-Like Behavior: Involvement of IL-6 Mediated Glucose Homeostasis Signaling.
PKM2-c-Myc-Survivin Cascade Regulates the Cell Proliferation, Migration, and Tamoxifen Resistance in Breast Cancer.
Effects of Xiaoyaosan on Depressive-Like Behaviors in Rats With Chronic Unpredictable Mild Stress Through HPA Axis Induced Astrocytic Activities.
Lian Hua Qing Wen Capsules, a Potent Epithelial Protector in Acute Lung Injury Model, Block Proapoptotic Communication Between Macrophages, and Alveolar Epithelial Cells.
ARP-1 Regulates the Transcriptional Activity of the Aromatase Gene in the Mouse Brain.
Scutellarein inhibits BLM-mediated pulmonary fibrosis by affecting fibroblast differentiation, proliferation, and apoptosis.
MicroRNA-34a Inhibition Alleviates Lung Injury in Cecal Ligation and Puncture Induced Septic Mice.
PPARγ as an E3 Ubiquitin-Ligase Impedes Phosphate-Stat6 Stability and Promotes Prostaglandins E(2)-Mediated Inhibition of IgE Production in Asthma.
Schisandrin B Inhibits Osteoclastogenesis and Protects Against Ovariectomy-Induced Bone Loss.
Toddalolactone Protects Lipopolysaccharide-Induced Sepsis and Attenuates Lipopolysaccharide-Induced Inflammatory Response by Modulating HMGB1-NF-κB Translocation.
MiR-10a-5p-Mediated Syndecan 1 Suppression Restricts Porcine Hemagglutinating Encephalomyelitis Virus Replication.
Eye Drops of Metformin Prevents Fibrosis After Glaucoma Filtration Surgery in Rats via Activating AMPK/Nrf2 Signaling Pathway.
CoenzymeQ10-Induced Activation of AMPK-YAP-OPA1 Pathway Alleviates Atherosclerosis by Improving Mitochondrial Function, Inhibiting Oxidative Stress and Promoting Energy Metabolism.
A miR-146a-5p/TRAF6/NF-kB p65 axis regulates pancreatic cancer chemoresistance: functional validation and clinical significance.
α1,6-Fucosyltransferase (FUT8) regulates the cancer-promoting capacity of cancer-associated fibroblasts (CAFs) by modifying EGFR core fucosylation (CF) in non-small cell lung cancer (NSCLC).
Cardio-renal Exosomes in Myocardial Infarction Serum Regulate Proangiogenic Paracrine Signaling in Adipose Mesenchymal Stem Cells.
Theta-burst transcranial magnetic stimulation promotes stroke recovery by vascular protection and neovascularization.
Graphene oxide improves postoperative cognitive dysfunction by maximally alleviating amyloid beta burden in mice.
Targeting BCL10 by small peptides for the treatment of B cell lymphoma.
Flubendazole elicits anti-cancer effects via targeting EVA1A-modulated autophagy and apoptosis in Triple-negative Breast Cancer.
Protein acetylation derepresses Serotonin Synthesis to potentiate Pancreatic Beta-Cell Function through HDAC1-PKA-Tph1 signaling.
Homozygous MESP1 knock-in reporter hESCs facilitated cardiovascular cell differentiation and myocardial infarction repair.
Extracellular vesicle-mediated delivery of miR-101 inhibits lung metastasis in osteosarcoma.
Aberrant miR-1246 expression promotes radioresistance in non-small cell lung cancer: a potential prognostic biomarker and radiotherapy sensitization target.
KLF13 suppresses the proliferation and growth of colorectal cancer cells through transcriptionally inhibiting HMGCS1-mediated cholesterol biosynthesis.
TIPE Regulates DcR3 Expression and Function by Activating the PI3K/AKT Signaling Pathway in CRC.
Forkhead Box Q1 Is Critical to Angiogenesis and Macrophage Recruitment of Colorectal Cancer.
Up-regulation of L Antigen Family Member 3 Associates With Aggressive Progression of Breast Cancer.
A Natural Dietary Flavone Myricetin as an α-Hemolysin Inhibitor for Controlling Staphylococcus aureus Infection.
Steroid 5α-Reductase Type I Induces Cell Viability and Migration via Nuclear Factor-κB/Vascular Endothelial Growth Factor Signaling Pathway in Colorectal Cancer.
The SIRT6-Autophagy-Warburg Effect Axis in Papillary Thyroid Cancer.
Methylation-Induced Silencing of ALDH2 Facilitates Lung Adenocarcinoma Bone Metastasis by Activating the MAPK Pathway.
Prognostic and Clinicopathological Significance of X-Box-Binding Protein 1 and N-Acetyltransferase 1 in Gallbladder Cancer.
NLRP6 contributes to inflammation and brain injury following intracerebral haemorrhage by activating autophagy.
Low-dose naltrexone inhibits the epithelial-mesenchymal transition of cervical cancer cells in vitro and effects indirectly on tumor-associated macrophages in vivo.
Increased regulatory T cells and eosinophils characterize atopic dermatitis-like graft-versus-host disease compared with lichen planus-like graft-versus-host disease.
Sublethal Levels of Antibiotics Promote Bacterial Persistence in Epithelial Cells.
Mitochondrial Transplantation Attenuates Brain Dysfunction in Sepsis by Driving Microglial M2 Polarization.
S-palmitoylation of swine interferon-inducible transmembrane protein is essential for its anti-JEV activity.
Deficiency of Grx1 leads to high sensitivity of HeLaS3 cells to oxidative stress via excessive accumulation of intracellular oxidants including ROS.
Estrogen Exerts Neuroprotective Effects in Vascular Dementia Rats by Suppressing Autophagy and Activating the Wnt/β-Catenin Signaling Pathway.
MCC950 Inhibits NLRP3 Inflammasome and Alleviates Axonal Injures in Early Stages of Diffuse Axonal Injury in Rats.
A novel GNAS-mutated human induced pluripotent stem cell model for understanding GNAS-mutated tumors.
Visualization of translocator protein (18 kDa) (TSPO) in the retina of diabetic retinopathy rats using fluorine-18-DPA-714.
SRSF10 inhibits the polymerase activity and replication of avian influenza virus by regulating the alternative splicing of chicken ANP32A.
The deubiquitylase USP2 maintains ErbB2 abundance via counteracting endocytic degradation and represents a therapeutic target in ErbB2-positive breast cancer.
RUNX3-dependent oxidative epithelial-to-mesenchymal transition in methamphetamine-induced chronic lung injury.
ACE2 modulates glucose homeostasis through GABA signaling during metabolic stress.
Musashi2 promotes the progression of pancreatic cancer through a novel ISYNA1-p21/ZEB-1 pathway.
Tacrolimus ameliorates tubulointerstitial inflammation in diabetic nephropathy via inhibiting the NFATc1/TRPC6 pathway.
Knockdown of endogenous RNF4 exacerbates ischaemia-induced cardiomyocyte apoptosis in mice.
Rosamultin Attenuates Acute Hypobaric Hypoxia-Induced Bone Injuries by Regulation of Sclerostin and Its Downstream Signals.
Polyphyllin II inhibits human bladder cancer migration and invasion by regulating EMT-associated factors and MMPs.
Sirtuin 3-mediated deacetylation of acyl-CoA synthetase family member 3 by protocatechuic acid attenuates non-alcoholic fatty liver disease.
Methamphetamine induces GSDME-dependent cell death in hippocampal neuronal cells through the endoplasmic reticulum stress pathway.
Inhibition of NK1R attenuates LPS-induced microglial inflammation and consequent death of PC12 cells.
NS5-V372A and NS5-H386Y variations are responsible for differences in interferon α/β induction and co-contribute to the replication advantage of Japanese encephalitis virus genotype I over genotype III in ducklings.
H63D variant of the homeostatic iron regulator (HFE) gene alters α-synuclein expression, aggregation, and toxicity.
Interleukin-18 levels in the hippocampus and behavior of adult rat offspring exposed to prenatal restraint stress during early and late pregnancy.
Control the fate of human umbilical cord mesenchymal stem cells with dual-enzymatically cross-linked gelatin hydrogels for potential applications in nerve regeneration.
Duck IFIT5 differentially regulates Tembusu virus replication and inhibits virus-triggered innate immune response.
The effect of monotropein on alleviating cisplatin-induced acute kidney injury by inhibiting oxidative damage, inflammation and apoptosis.
Dual PI3K/mTOR inhibitor PKI-402 suppresses the growth of ovarian cancer cells by degradation of Mcl-1 through autophagy.
SOCS3-deficient lung epithelial cells uptaking neutrophil-derived SOCS3 worsens lung influenza infection.
The roles of grouper TANK in innate immune defense against iridovirus and nodavirus infections.
Zinc exerts its renal protection effect on arsenic-exposed common carp: A signaling network comprising Nrf2, NF-κB and MAPK pathways.
S-allyl-L-cysteine protects hepatocytes from indomethacin-induced apoptosis by attenuating endoplasmic reticulum stress.
HEATR1 promotes proliferation in gastric cancer in vitro and in vivo.
Autocrine INSL5 promotes tumor progression and glycolysis via activation of STAT5 signaling.
Circular RNA circREPS2 Acts as a Sponge of miR-558 to Suppress Gastric Cancer Progression by Regulating RUNX3/β-catenin Signaling.
The microRNA/TET3/REST axis is required for olfactory globose basal cell proliferation and male behavior.
Oxidative stress mediates the apoptosis and epigenetic modification of the Bcl-2 promoter via DNMT1 in a cigarette smoke-induced emphysema model.
Myricanol 5-fluorobenzyloxy ether regulation of survivin pathway inhibits human lung adenocarcinoma A549 cells growth in vitro.
Characterization of Low Molecular Weight Sulfate Ulva Polysaccharide and its Protective Effect against IBD in Mice.
NOD2/c-Jun NH(2)-Terminal Kinase Triggers Mycoplasma ovipneumoniae-Induced Macrophage Autophagy.
L-Theanine affects intestinal mucosal immunity by regulating short-chain fatty acid metabolism under dietary fiber feeding.
Astaxanthin attenuates oxidative stress and immune impairment in D-galactose-induced aging in rats by activating the Nrf2/Keap1 pathway and suppressing the NF-κB pathway.
Neural progenitor cell pyroptosis contributes to Zika virus-induced brain atrophy and represents a therapeutic target.
(+)-Clausenamide protects against drug-induced liver injury by inhibiting hepatocyte ferroptosis.
Overexpression of MicroRNA-9a-5p Ameliorates NLRP1 Inflammasome-mediated Ischemic Injury in Rats Following Ischemic Stroke.
Inhibition of autophagy enhances timosaponin AIII-induced lung cancer cell apoptosis and anti-tumor effect in vitro and in vivo.
Inflammasome/NF-κB translocation inhibition via PPARγ agonist mitigates inorganic mercury induced nephrotoxicity.
FUT9-Driven Programming of Colon Cancer Cells towards a Stem Cell-Like State.
Adenovirus-mediated specific tumor tagging facilitates CAR-T therapy against antigen-mismatched solid tumors.
The AKT/GSK3-Mediated Slug Expression Contributes to Oxaliplatin Resistance in Colorectal Cancer via Upregulation of ERCC1.
Combination of luteolin and lycopene effectively protect against the "two-hit" in NAFLD through Sirt1/AMPK signal pathway.
Four active monomers from Moutan Cortex exert inhibitory effects against oxidative stress by activating Nrf2/Keap1 signaling pathway.
Herpes Simplex Virus Type 2 Inhibits Type I IFN Signaling Mediated by the Novel E3 Ubiquitin Protein Ligase Activity of Viral Protein ICP22.
Targeting SLC7A11 specifically suppresses the progression of colorectal cancer stem cells via inducing ferroptosis.
Stimulation of endothelial progenitor cells by microRNA-31a-5p to induce endothelialization in an aneurysm neck after coil embolization by modulating the Axin1-mediated β-catenin/vascular endothelial growth factor pathway.
Expression Level of Small Envelope Protein in Addition to Sequence Divergence inside Its Major Hydrophilic Region Contributes to More Efficient Surface Antigen Secretion by Hepatitis B Virus Subgenotype D2 than Subgenotype A2.
Down-regulation of NTSR3 inhibits cell growth and metastasis, as well as the PI3K-AKT and MAPK signaling pathways in colorectal cancer.
Cytotoxic effects of vitamins K1, K2, and K3 against human T lymphoblastoid leukemia cells through apoptosis induction and cell cycle arrest.
Ubiquitin specific protease 5 negatively regulates the IFNs-mediated antiviral activity via targeting SMURF1.
Lycopene protects neuroblastoma cells against oxidative damage via depression of ER stress.
Upregulation of secreted phosphoprotein 1 affects malignant progression, prognosis, and resistance to cetuximab via the KRAS/MEK pathway in head and neck cancer.
Resveratrol modulates the apoptosis and autophagic death of human lung adenocarcinoma A549 cells via a p53‑dependent pathway: Integrated bioinformatics analysis and experimental validation.
Schisandrin A restrains osteoclastogenesis by inhibiting reactive oxygen species and activating Nrf2 signalling.
YY1-mediated PTEN dephosphorylation antagonizes IR-induced DNA repair contributing to tongue squamous cell carcinoma radiosensitization.
Spatiotemporal expression of neurogenic locus notch homolog protein 1 in developing caudal spinal cord of fetuses with anorectal malformations from ETU-fed rats.
Silica nanoparticles induce spermatogenesis disorders via L3MBTL2-DNA damage-p53 apoptosis and RNF8-ubH2A/ubH2B pathway in mice.
Autophagy plays a protective role during Pseudomonas aeruginosa-induced apoptosis via ROS-MAPK pathway.
LKB1-MARK2 signalling mediates lipopolysaccharide-induced production of cytokines in mouse macrophages.
Dihydrotanshinone I inhibits ovarian cancer cell proliferation and migration by transcriptional repression of PIK3CA gene.
KIAA1429 regulates cell proliferation by targeting c-Jun messenger RNA directly in gastric cancer.
Silencing long non‑coding RNA NEAT1 suppresses the tumorigenesis of infantile hemangioma by competitively binding miR‑33a‑5p to stimulate HIF1α/NF‑κB pathway.
Arsenic (III) and/or copper (II) induces oxidative stress in chicken brain and subsequent effects on mitochondrial homeostasis and autophagy.
Dihydrotanshinone I inhibits human glioma cell proliferation via the activation of ferroptosis.
Essential roles of S100A10 in Toll-like receptor signaling and immunity to infection.
miR-103a-3p regulates mitophagy in Parkinson's disease through Parkin/Ambra1 signaling.
p53 promotes ZDHHC1-mediated IFITM3 palmitoylation to inhibit Japanese encephalitis virus replication.
A Histomorphological Study of the Divergent Corpus Spongiosum Surrounding the Urethral Plate in Hypospadias.
Exosomal miR-1255b-5p targets human telomerase reverse transcriptase in colorectal cancer cells to suppress epithelial-to-mesenchymal transition.
Polydatin alleviates parkinsonism in MPTP-model mice by enhancing glycolysis in dopaminergic neurons.
Proteomic analyses reveal that Orf virus induces the activation and maturation of mouse bone marrow-derived dendritic cells.
Biomechanically reduced expression of Derlin-3 is linked to the apoptosis of chondrocytes in the mandibular condylar cartilage via the endoplasmic reticulum stress pathway.
T-type calcium channel blockade induces apoptosis in C2C12 myotubes and skeletal muscle via endoplasmic reticulum stress activation.
Impaired NLRP3 inflammasome activation/pyroptosis leads to robust inflammatory cell death via caspase-8/RIPK3 during coronavirus infection.
Calreticulin promotes EMT in pancreatic cancer via mediating Ca(2+) dependent acute and chronic endoplasmic reticulum stress.
Profiling pro-neural to mesenchymal transition identifies a lncRNA signature in glioma.
Revealing active ingredients, potential targets, and action mechanism of Ermiao fang for treating endometritis based on network pharmacology strategy.
c-Myc inactivation of p53 through the pan-cancer lncRNA MILIP drives cancer pathogenesis.
Defect of SLC38A3 promotes epithelial-mesenchymal transition and predicts poor prognosis in esophageal squamous cell carcinoma.
Transcriptomic and Proteomic Analysis Reveals Mechanisms of Patulin-Induced Cell Toxicity in Human Embryonic Kidney Cells.
Anticancer Effects of Honokiol via Mitochondrial Dysfunction Are Strongly Enhanced by the Mitochondria-Targeting Carrier Berberine.
Rosmarinic Acid Alleviates Inflammation, Apoptosis, and Oxidative Stress through Regulating miR-155-5p in a Mice Model of Parkinson's Disease.
miR-497 regulates fatty acid synthesis via LATS2 in bovine mammary epithelial cells.
Amorphous silica nanoparticles accelerated atherosclerotic lesion progression in ApoE(-/-) mice through endoplasmic reticulum stress-mediated CD36 up-regulation in macrophage.
Sodium butyrate promotes milk fat synthesis in bovine mammary epithelial cells via GPR41 and its downstream signalling pathways.
Designing an eEF2K-Targeting PROTAC small molecule that induces apoptosis in MDA-MB-231 cells.
Sestrin2 promotes angiogenesis to alleviate brain injury by activating Nrf2 through regulating the interaction between p62 and Keap1 following photothrombotic stroke in rats.
Upregulation of Glutaredoxin 2 alleviates oxygen-glucose deprivation/reoxygenation-induced apoptosis and ROS production in neurons by enhancing Nrf2 signaling via modulation of GSK-3β.
A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters.
Polydatin executes anticancer effects against glioblastoma multiforme by inhibiting the EGFR-AKT/ERK1/2/STAT3-SOX2/Snail signaling pathway.
Notch1 contributes to TNF-α-induced proliferation and migration of airway smooth muscle cells through regulation of the Hes1/PTEN axis.
Knockdown of fatty acid binding protein 4 exacerbates Bacillus Calmette-Guerin infection-induced RAW264.7 cell apoptosis via the endoplasmic reticulum stress pathway.
Enhanced therapeutic efficacy of a novel colon-specific nanosystem loading emodin on DSS-induced experimental colitis.
CaMKII as a key regulator of contrast-induced nephropathy through mPTP opening in HK-2 cells.
Histone demethylase Jmjd3 modulates osteoblast apoptosis induced by tumor necrosis factor-alpha through directly targeting RASSF5.
RNA binding motif protein 10 suppresses lung cancer progression by controlling alternative splicing of eukaryotic translation initiation factor 4H.
Spatiotemporal heterogeneity of PPARγ expression in porcine uteroplacenta for regulating of placental angiogenesis through VEGF-mediated signalling.
Identification of octopus peptide and its promotion of β-casein synthesis in a mouse mammary epithelial cell line.
Low-intensity pulsed ultrasound protects subchondral bone in rabbit temporomandibular joint osteoarthritis by suppressing TGF-β1/Smad3 pathway.
Involvement of NMDAR/PSD-95/nNOS-NO-cGMP pathway in embryonic exposure to BPA induced learning and memory dysfunction of rats.
Long noncoding RNA LINC00346 promotes glioma cell migration, invasion and proliferation by up-regulating ROCK1.
MicroRNA-127-5p impairs function of granulosa cells via HMGB2 gene in premature ovarian insufficiency.
Oxidative stress is important in the pathogenesis of stress-related mucosal disease.
Brilliant blue G attenuates neuro-inflammation via regulating MAPKs and NF-κB signaling pathways in lipopolysaccharide-induced BV2 microglia cells.
Methylprednisolone potentiates tetrandrine pharmacodynamics against human T lymphoblastoid leukemia MOLT-4 cells via regulation of NF-κB activation and cell cycle transition.
Activation of angiotensin II type-2 receptor protects against cigarette smoke-induced COPD.
Up-regulation of astrocyte excitatory amino acid transporter 2 alleviates central sensitization in a rat model of chronic migraine.
TRIM25 upregulation by Mycobacterium tuberculosis infection promotes intracellular survival of M.tb in RAW264.7 cells.
Indirubin alleviates bleomycin-induced pulmonary fibrosis in mice by suppressing fibroblast to myofibroblast differentiation.
Nucleoredoxin interaction with flightless-I/actin complex is differentially altered in alcoholic liver disease.
Mycoplasma bovis-generated reactive oxygen species and induced apoptosis in bovine mammary epithelial cell cultures.
Sox13 promotes hepatocellular carcinoma metastasis by transcriptionally activating Twist1.
TMEM176A acts as a tumor suppressor gene in pancreatic cancer by inhibiting ERK signaling.
Deficiency of microglial Hv1 channel is associated with activation of autophagic pathway and ROS production in LPC-induced demyelination mouse model.
Effects of Osthole on Progesterone Secretion in Chicken Preovulatory Follicles Granulosa Cells.
Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation.
Anthocyanins decrease the internalization of TiO(2) nanoparticles into 3D Caco-2 spheroids.
Hypoxia induces sorafenib resistance mediated by autophagy via activating FOXO3a in hepatocellular carcinoma.
Effective RNA Knockdown Using CRISPR-Cas13a and Molecular Targeting of the EML4-ALK Transcript in H3122 Lung Cancer Cells.
MiR-103a-3p promotes tumour glycolysis in colorectal cancer via hippo/YAP1/HIF1A axis.
Velvet antler polypeptide prevents the disruption of hepatic tight junctions via inhibiting oxidative stress in cholestatic mice and liver cell lines.
Identification of Milk Fat Metabolism-Related Pathways of the Bovine Mammary Gland during Mid and Late Lactation and Functional Verification of the ACSL4 Gene.
Eurocristatine, a plant alkaloid from Eurotium cristatum, alleviates insulin resistance in db/db diabetic mice via activation of PI3K/AKT signaling pathway.
Baicalein ameliorates ionizing radiation-induced injuries by rebalancing gut microbiota and inhibiting apoptosis.
A novel polysaccharide from Acorus tatarinowii protects against LPS-induced neuroinflammation and neurotoxicity by inhibiting TLR4-mediated MyD88/NF-κB and PI3K/Akt signaling pathways.
Binding properties of marine bromophenols with human protein tyrosine phosphatase 1B: Molecular docking, surface plasmon resonance and cellular insulin resistance study.
Targeting HMGB3/hTERT axis for radioresistance in cervical cancer.
Synergism of TNF-α and IFN-γ triggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes.
Duck enteritis virus pUL47, as a late structural protein localized in the nucleus, mainly depends on residues 40 to 50 and 768 to 777 and inhibits IFN-β signalling by interacting with STAT1.
Immunoproteasome is up-regulated in rotenone-induced Parkinson's disease rat model.
Berberine inhibits proliferation and induces G0/G1 phase arrest in colorectal cancer cells by downregulating IGF2BP3.
iTRAQ-based quantitative proteomic analysis of the therapeutic effects of 2% hydrogen gas inhalation on brain injury in septic mice.
Combination of N, N'-dicyclohexyl-N-arachidonic acylurea and tacrolimus prolongs cardiac allograft survival in mice.
Long non-coding RNA OIP5-AS1 promotes pancreatic cancer cell growth through sponging miR-342-3p via AKT/ERK signaling pathway.
Role of fucosyltransferase IV in the migration and invasion of human melanoma cells.
OGDHL silencing promotes hepatocellular carcinoma by reprogramming glutamine metabolism.
miR-142-5P regulates triglyceride by targeting CTNNB1 in goat mammary epithelial cells.
Transcriptome sequencing analysis of mono‑ADP‑ribosylation in colorectal cancer cells.
Annexin-1 Mimetic Peptide Ac2-26 Suppresses Inflammatory Mediators in LPS-Induced Astrocytes and Ameliorates Pain Hypersensitivity in a Rat Model of Inflammatory Pain.
Mitochondrial dysfunction is involved in aristolochic acid I-induced apoptosis in renal proximal tubular epithelial cells.
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
Programmable prodrug micelle with size-shrinkage and charge-reversal for chemotherapy-improved IDO immunotherapy.
Lin28a protects against diabetic cardiomyopathy through Mst1 inhibition.
PM2.5 in poultry houses synergizes with Pseudomonas aeruginosa to aggravate lung inflammation in mice through the NF-κB pathway.
Shear stress stimulates integrin β1 trafficking and increases directional migration of cancer cells via promoting deacetylation of microtubules.
TOPORS, a tumor suppressor protein, contributes to the maintenance of higher-order chromatin architecture.
Protective effect of cilastatin against diclofenac-induced nephrotoxicity through interaction with diclofenac acyl glucuronide via organic anion transporters.
Palmatine induces G2/M phase arrest and mitochondrial-associated pathway apoptosis in colon cancer cells by targeting AURKA.
Protective effect of ginsenoside Rg5 against kidney injury via inhibition of NLRP3 inflammasome activation and the MAPK signaling pathway in high-fat diet/streptozotocin-induced diabetic mice.
Elevated SRC3 expression predicts pemetrexed resistance in lung adenocarcinoma.
LncRNA MFI2-AS1 promotes HCC progression and metastasis by acting as a competing endogenous RNA of miR-134 to upregulate FOXM1 expression.
Protein kinase CK2 participates in estrogen-mediated endothelial progenitor cell homing to endometriotic lesions through stromal cells in a stromal cell-derived factor-1- CXCR4-dependent manner.
BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma.
Suppression of experimental atrial fibrillation in a canine model of rapid atrial pacing by the phosphodiesterase 3 inhibitor cilostazol.
Mitochondria-related miR-574 reduces sperm ATP by targeting ND5 in aging males.
Rare Neurologic Disease-Associated Mutations of AIMP1 are Related with Inhibitory Neuronal Differentiation Which is Reversed by Ibuprofen.
Artesunate attenuates 2, 4-dinitrochlorobenzene-induced atopic dermatitis by down-regulating Th17 cell responses in BALB/c mice.
Effect of miR-195-5p on cardiomyocyte apoptosis in rats with heart failure by regulating TGF-β1/Smad3 signaling pathway.
TET2-mediated Cdkn2A DNA hydroxymethylation in midbrain dopaminergic neuron injury of Parkinson's disease.
The Lumiptosome, an engineered luminescent form of the apoptosome can report cell death by using the same Apaf-1 dependent pathway.
P-21-activated kinase 1 contributes to tumor angiogenesis upon photodynamic therapy via the HIF-1α/VEGF pathway.
Neddylation-mediated Nedd4-2 activation regulates ubiquitination modification of renal NBCe1.
Concentration and Duration of Indoxyl Sulfate Exposure Affects Osteoclastogenesis by Regulating NFATc1 via Aryl Hydrocarbon Receptor.
Androgen aggravates liver fibrosis by activation of NLRP3 inflammasome in CCl(4)-induced liver injury mouse model.
In vitro and in vivo anti-Listeria effect of Succinoglycan Riclin through regulating MAPK/IL-6 axis and metabolic profiling.
Blueberry Prevents the Bladder Dysfunction in Bladder Outlet Obstruction Rats by Attenuating Oxidative Stress and Suppressing Bladder Remodeling.
Ketamine attenuates high-glucose-mediated endothelial inflammation in human umbilical vein endothelial cells.
Interleukin-4 Restores Insulin Sensitivity in Insulin-Resistant Osteoblasts by Increasing the Expression of Insulin Receptor Substrate 1.
NLRP6 expressed in astrocytes aggravates neurons injury after OGD/R through activating the inflammasome and inducing pyroptosis.
Dihydroartemisinin inhibits the proliferation of IgAN mesangial cells through the mTOR signaling pathway.
JTE-013 supplementation improves erectile dysfunction in rats with streptozotocin-induced type Ⅰ diabetes through the inhibition of the rho-kinase pathway, fibrosis, and apoptosis.
Danshen formula granule and salvianic acid A alleviate ethanol-induced neurotoxicity.
Resveratrol protects the integrity of alveolar epithelial barrier via SIRT1/PTEN/p-Akt pathway in methamphetamine-induced chronic lung injury.
Integrin β3 Modulates TLR4-Mediated Inflammation by Regulation of CD14 Expression in Macrophages in Septic Condition.
Inhibitory mechanism of muscone in liver cancer involves the induction of apoptosis and autophagy.
Samarium enriches antitumor activity of ZnO nanoparticles via downregulation of CXCR4 receptor and cytochrome P450.
Cyclovirobuxine D Exerts Anticancer Effects by Suppressing the EGFR-FAK-AKT/ERK1/2-Slug Signaling Pathway in Human Hepatocellular Carcinoma.
Lysophosphatidic acid receptor 4 regulates osteogenic and adipogenic differentiation of progenitor cells via inactivation of RhoA/ROCK1/β-catenin signaling.
HUWE1 promotes EGFR ubiquitination and degradation to protect against renal tubulointerstitial fibrosis.
Molecular hydrogen regulates PTEN-AKT-mTOR signaling via ROS to alleviate peritoneal dialysis-related peritoneal fibrosis.
Recombinant Human Milk Fat Globule-Epidermal Growth Factor 8 Attenuates Microthrombosis after Subarachnoid Hemorrhage in Rats.
Blockade of HSP70 by VER-155008 synergistically enhances bortezomib-induced cytotoxicity in multiple myeloma.
The marine-derived furanone reduces intracellular lipid accumulation in vitro by targeting LXRα and PPARα.
Mechanism of the hypoxia inducible factor 1/hypoxic response element pathway in rat myocardial ischemia/diazoxide post‑conditioning.
Ginsenosides reduce body weight and ameliorate hepatic steatosis in high fat diet‑induced obese mice via endoplasmic reticulum stress and p‑STAT3/STAT3 signaling.
Cystatin C promotes cognitive dysfunction in rats with cerebral microbleeds by inhibiting the ERK/synapsin Ia/Ib pathway.
WHIMP links the actin nucleation machinery to Src-family kinase signaling during protrusion and motility.
LongShengZhi capsule inhibits doxorubicin-induced heart failure by anti-oxidative stress.
The mechanism of PDA/PEI/5-Fu coated esophageal stent material on inhibiting cancer associated pathological cells.
DJ-1 exerts anti-inflammatory effects and regulates NLRX1-TRAF6 via SHP-1 in stroke.
Transcription co-activator P300 activates Elk1-aPKC-ι signaling mediated epithelial-to-mesenchymal transition and malignancy in hepatocellular carcinoma.
Quantitative Mitochondrial Proteomics Reveals ANXA7 as a Crucial Factor in Mitophagy.
miR-17 regulates the proliferation and differentiation of retinal progenitor cells by targeting CHMP1A.
SIRT3 inhibits cardiac hypertrophy by regulating PARP-1 activity.
BCAP31, a cancer/testis antigen-like protein, can act as a probe for non-small-cell lung cancer metastasis.
(20S)G-Rh2 Inhibits NF-κB Regulated Epithelial-Mesenchymal Transition by Targeting Annexin A2.
5-HT(1A)R alleviates Aβ-induced cognitive decline and neuroinflammation through crosstalk with NF-κB pathway in mice.
The Agpat4/LPA axis in colorectal cancer cells regulates antitumor responses via p38/p65 signaling in macrophages.
LINC00978 promotes hepatocellular carcinoma carcinogenesis partly via activating the MAPK/ERK pathway.
Posttranslational lysine 2-hydroxyisobutyrylation of human sperm tail proteins affects motility.
Design, Synthesis, and Biological Evaluation of Imidazo[1,2-a]pyridine Derivatives as Novel PI3K/mTOR Dual Inhibitors.
Dendrobium officinale polysaccharides protected against ethanol-induced acute liver injury in vivo and in vitro via the TLR4/NF-κB signaling pathway.
Optimization of Experimental Variables Influencing Apoptosome Biosensor in HEK293T Cells.
Protective effects of panax notoginseng saponin on dextran sulfate sodium-induced colitis in rats through phosphoinositide-3-kinase protein kinase B signaling pathway inhibition.
Extrahepatic deficiency of transferrin receptor 2 is associated with increased erythropoiesis independent of iron overload.
Dual regulation of p53 by the ribosome maturation factor SBDS.
Regulation of the linear ubiquitination of STAT1 controls antiviral interferon signaling.
HNF-1a promotes pancreatic cancer growth and apoptosis resistance via its target gene PKLR.
Alarmin HMGB1 Plays a Detrimental Role in Hippocampal Dysfunction Caused by Hypoxia-Ischemia Insult in Neonatal Mice: Evidence from the Application of the HMGB1 Inhibitor Glycyrrhizin.
Identification of ALPPL2 as a Naive Pluripotent State-Specific Surface Protein Essential for Human Naive Pluripotency Regulation.
TXNIP deficiency mitigates podocyte apoptosis via restraining the activation of mTOR or p38 MAPK signaling in diabetic nephropathy.
Synergetic inhibition of daidzein and regular exercise on breast cancer in bearing-4T1 mice by regulating NK cells and apoptosis pathway.
Neuronal BIN1 Regulates Presynaptic Neurotransmitter Release and Memory Consolidation.
HIF2-Induced Long Noncoding RNA RAB11B-AS1 Promotes Hypoxia-Mediated Angiogenesis and Breast Cancer Metastasis.
Microcystins-LR induced apoptosis via S-nitrosylation of GAPDH in colorectal cancer cells.
Ferulic acid isolated from propolis inhibits porcine parvovirus replication potentially through Bid-mediate apoptosis.
Histone demethylase KDM4A regulates adipogenic and osteogenic differentiation via epigenetic regulation of C/EBPα and canonical Wnt signaling.
ARHGEF38 as a novel biomarker to predict aggressive prostate cancer.
Reversing a model of Parkinson's disease with in situ converted nigral neurons.
MiR-153-3p induces immune dysregulation by inhibiting PELI1 expression in umbilical cord-derived mesenchymal stem cells in patients with systemic lupus erythematosus.
PAQR3 protects against oxygen-glucose deprivation/reperfusion-induced injury through the ERK signaling pathway in N2A cells.
Clinical significance of sHER2‑ECD and calpain‑10 expression in tumor tissues of patients with breast cancer.
Esculetin Ameliorates Lipopolysaccharide-Induced Acute Lung Injury in Mice Via Modulation of the AKT/ERK/NF-κB and RORγt/IL-17 Pathways.
Quercetin suppresses migration and invasion by targeting miR-146a/GATA6 axis in fibroblast-like synoviocytes of rheumatoid arthritis.
Inhibition of miR-574-5p suppresses cell growth and metastasis and enhances chemosensitivity by targeting RNA binding protein QKI in cervical cancer cells.
Human placenta derived mesenchymal stromal cells alleviate GVHD by promoting the generation of GSH and GST in PD-1(+)T cells.
Regulatory T cell is critical for interleukin-33-mediated neuroprotection against stroke.
SUMOylation of vascular endothelial growth factor receptor 2 inhibits the proliferation, migration, and angiogenesis signaling pathway in non-small cell lung cancer.
Tizoxanide mitigates inflammatory response in LPS-induced neuroinflammation in microglia via restraining p38/MAPK pathway.
Astrocyte elevated gene 1 (AEG-1) promotes anoikis resistance and metastasis by inducing autophagy in hepatocellular carcinoma.
Disregulation of Autophagy in the Transgenerational Cc2d1a Mouse Model of Autism.
The Activation of Heat-Shock Protein After Copper(II) and/or Arsenic(III)-Induced Imbalance of Homeostasis, Inflammatory Response in Chicken Rectum.
BRM-SWI/SNF chromatin remodeling complex enables functional telomeres by promoting co-expression of TRF2 and TRF1.
Sustained mitochondrial biogenesis is essential to maintain caloric restriction-induced beige adipocytes.
Tolfenamic acid inhibits GSK-3β and PP2A mediated tau hyperphosphorylation in Alzheimer's disease models.
Highly expressed STAT1 contributes to the suppression of stemness properties in human paclitaxel-resistant ovarian cancer cells.
Arsenic induces dysfunctional autophagy via dual regulation of mTOR pathway and Beclin1-Vps34/PI3K complex in MLTC-1 cells.
The GTPase Rab27b regulates the release, autophagic clearance, and toxicity of α-synuclein.
BDH2 triggers ROS-induced cell death and autophagy by promoting Nrf2 ubiquitination in gastric cancer.
Enterovirus A71 Oncolysis of Malignant Gliomas.
Cytoplasmic PCNA is located in the actin belt and involved in osteoclast differentiation.
MiR-377-3p inhibits atherosclerosis-associated vascular smooth muscle cell proliferation and migration via targeting neuropilin2.
Molecular mechanism of targeted inhibition of HMGA2 via miRNAlet-7a in proliferation and metastasis of laryngeal squamous cell carcinoma.
Opening large-conductance potassium channels selectively induced cell death of triple-negative breast cancer.
Enhanced autophagic retrograde axonal transport by dynein intermediate chain upregulation improves Aβ clearance and cognitive function in APP/PS1 double transgenic mice.
L-3-n-butylphthalide attenuates inflammation response and brain edema in rat intracerebral hemorrhage model.
A Gold(I) Complex Containing an Oleanolic Acid Derivative as a Potential Anti-Ovarian-Cancer Agent by Inhibiting TrxR and Activating ROS-Mediated ERS.
Excretory/secretory products of Angiostrongylus cantonensis fifth-stage larvae induce endoplasmic reticulum stress via the Sonic hedgehog pathway in mouse astrocytes.
Immune profiling reveals prognostic genes in high-grade serous ovarian cancer.
Neurotoxicity of aluminum oxide nanoparticles and their mechanistic role in dopaminergic neuron injury involving p53-related pathways.
Cerenkov luminescence imaging is an effective preclinical tool for assessing colorectal cancer PD-L1 levels in vivo.
Mechanism of Heshouwuyin inhibiting the Cyt c/Apaf-1/Caspase-9/Caspase-3 pathway in spermatogenic cell apoptosis.
Regulatory effects of Prohibitin 1 on proliferation and apoptosis of pulmonary arterial smooth muscle cells in monocrotaline-induced PAH rats.
Synergistic Effect of Benzethonium Chloride Combined with Endoxan against Hepatocellular Carcinoma in Rats through Targeting Apoptosis Signaling Pathway.
Fast and unbiased purification of RNA-protein complexes after UV cross-linking.
Daucosterol linolenate from Sweet Potato Suppresses MCF7-Xenograft-Tumor Growth through Regulating PI3K/AKT Pathway.
A novel homozygous nonsense ZP1 variant causes human female infertility associated with empty follicle syndrome (EFS).
Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation.
A mitophagic response to iron overload-induced oxidative damage associated with the PINK1/Parkin pathway in pancreatic beta cells.
lncRNA LA16c‑313D11.11 modulates the development of endometrial cancer by binding to and inhibiting microRNA‑205‑5p function and indirectly increasing PTEN activity.
Matrix Metalloproteinase 11 as a Novel Tumor Promoter and Diagnostic and Prognostic Biomarker for Pancreatic Ductal Adenocarcinoma.
Characterization of red ginseng-drug interaction by CYP3A activity increased in high dose administration in mice.
HMGB1-induced aberrant autophagy contributes to insulin resistance in granulosa cells in PCOS.
miR-196b-5p controls adipocyte differentiation and lipogenesis through regulating mTORC1 and TGF-β signaling.
Presynaptic Caytaxin prevents apoptosis via deactivating DAPK1 in the acute phase of cerebral ischemic stroke.
miR-203a suppresses cell proliferation by targeting RING-finger protein 6 in colorectal cancer.
Stomatin-like protein-2 confers neuroprotection effect in oxygen-glucose deprivation/reoxygenation-injured neurons by regulating AMPK/Nrf2 signalling.
Protective effect of quercetin on rat testes against cadmium toxicity by alleviating oxidative stress and autophagy.
BMP7 is Downregulated in Lumbosacral Spinal Cord of Rat Embryos With Anorectal Malformation.
Targeted immunomodulation of inflammatory monocytes across the blood-brain barrier by curcumin-loaded nanoparticles delays the progression of experimental autoimmune encephalomyelitis.
AMPH1 functions as a tumour suppressor in ovarian cancer via the inactivation of PI3K/AKT pathway.
SIRT2 suppresses expression of inflammatory factors via Hsp90-glucocorticoid receptor signalling.
CUDC-907, a novel dual PI3K and HDAC inhibitor, in prostate cancer: Antitumour activity and molecular mechanism of action.
The effect of lncRNA-ARAP1-AS2/ARAP1 on high glucose-induced cytoskeleton rearrangement and epithelial-mesenchymal transition in human renal tubular epithelial cells.
Reversal of prolonged obesity-associated cerebrovascular dysfunction by inhibiting microglial Tak1.
LHPP inhibits hepatocellular carcinoma cell growth and metastasis.
Melatonin protects against chronic stress-induced oxidative meiotic defects in mice MII oocytes by regulating SIRT1.
Human alkaline ceramidase 2 promotes the growth, invasion, and migration of hepatocellular carcinoma cells via sphingomyelin phosphodiesterase acid-like 3B.
Bisdemethoxycurcumin inhibits oxidative stress and antagonizes Alzheimer's disease by up-regulating SIRT1.
Pathological mutations in PNKP trigger defects in DNA single-strand break repair but not DNA double-strand break repair.
Integrative Proteomic Characterization of Human Lung Adenocarcinoma.
SLC7A2 serves as a potential biomarker and therapeutic target for ovarian cancer.
Protective effect of miRNA-containing extracellular vesicles derived from mesenchymal stromal cells of old rats on renal function in chronic kidney disease.
SNHG11 promotes cell proliferation in colorectal cancer by forming a positive regulatory loop with c-Myc.
The miR-1224-5p/TNS4/EGFR axis inhibits tumour progression in oesophageal squamous cell carcinoma.
Transcriptome Analysis of Testes and Uterus: Reproductive Dysfunction Induced by Toxoplasma gondii in Mice.
NLRP3 inflammasome-mediated microglial pyroptosis is critically involved in the development of post-cardiac arrest brain injury.
Innate Effector Systems in Primary Human Macrophages Sensitize Multidrug-Resistant Klebsiella pneumoniae to Antibiotics.
ZIC2 is downregulated and represses tumor growth via the regulation of STAT3 in breast cancer.
Impairment in dynein-mediated nuclear translocation by BICD2 C-terminal truncation leads to neuronal migration defect and human brain malformation.
Genetic variants in m6A modification genes are associated with esophageal squamous-cell carcinoma in the Chinese population.
Long non-coding RNA JPX correlates with poor prognosis and tumor progression in non-small-cell lung cancer by interacting with miR-145-5p and CCND2.
Excessive Mg(2+) Impairs Intestinal Homeostasis by Enhanced Production of Adenosine Triphosphate and Reactive Oxygen Species.
Carfilzomib inhibits the growth of lung adenocarcinoma via upregulation of Gadd45a expression.
Identification and characterization of c-raf from orange-spotted grouper (Epinephelus coioides).
MiR-203a-3p inhibits retinal angiogenesis and alleviates proliferative diabetic retinopathy in oxygen-induced retinopathy (OIR) rat model via targeting VEGFA and HIF-1α.
Calycosin-7-O-β-D-glucoside attenuates myocardial ischemia-reperfusion injury by activating JAK2/STAT3 signaling pathway via the regulation of IL-10 secretion in mice.
MiR-183-5p protects rat hearts against myocardial ischemia/reperfusion injury through targeting VDAC1.
Decreased ALCAM expression and promoter hypermethylation is associated with preeclampsia.
High Expression of c-Met, PKCλ and ALDH1A3 Predicts a Poor Prognosis in Late-stage Breast Cancer.
ALK(ATI) interacts with c-Myc and promotes cancer stem cell-like properties in sarcoma.
MnTBAP inhibits bone loss in ovariectomized rats by reducing mitochondrial oxidative stress in osteoblasts.
LncRNA SNHG3 promotes cell proliferation and invasion through the miR-384/hepatoma-derived growth factor axis in breast cancer.
Hydrogen sulfide attenuates cigarette smoke-induced airway remodeling by upregulating SIRT1 signaling pathway.
Human mesenchymal stem cells-derived conditioned medium inhibits hypoxia-induced death of neonatal porcine islets by inducing autophagy.
LncRNA HOXA11-AS regulates calcium oxalate crystal-induced renal inflammation via miR-124-3p/MCP-1.
Arsenic influences spermatogenesis by disorganizing the elongation of spermatids in adult male mice.
Endoplasmic reticulum stress regulates epithelial‑mesenchymal transition in human lens epithelial cells.
Effects of oral florfenicol on intestinal structure, function and microbiota in mice.
MicroRNA-138 inhibits tumor growth and enhances chemosensitivity in human cervical cancer by targeting H2AX.
REDD1 overexpression in oral squamous cell carcinoma may predict poor prognosis and correlates with high microvessel density.
USP12 translocation maintains interferon antiviral efficacy by inhibiting CBP acetyltransferase activity.
The novel thioredoxin reductase inhibitor A-Z2 triggers intrinsic apoptosis and shows efficacy in the treatment of acute myeloid leukemia.
Osthole inhibits cell proliferation by regulating the TGF-β1/Smad/p38 signaling pathways in pulmonary arterial smooth muscle cells.
Tandem mass tag (TMT) proteomic analysis of fetal lungs revealed differential expression of tight junction proteins in a rat model of congenital diaphragmatic hernia.
Activation of CD137 signaling promotes neointimal formation by attenuating TET2 and transferrring from endothelial cell-derived exosomes to vascular smooth muscle cells.
LncRNA GAS5 exacerbates renal tubular epithelial fibrosis by acting as a competing endogenous RNA of miR-96-5p.
Isolated Erythrocytosis Associated With 3 Novel Missense Mutations in the EGLN1 Gene.
Acetyltransferase GCN5 regulates autophagy and lysosome biogenesis by targeting TFEB.
5-(3,4,5-trimethoxybenzoyl)-4-methyl-2-(p-tolyl) imidazol (BZML) targets tubulin and DNA to induce anticancer activity and overcome multidrug resistance in colorectal cancer cells.
Resveratrol targets PD-L1 glycosylation and dimerization to enhance antitumor T-cell immunity.
The tight junction protein TJP1 regulates the feeding-modulated hepatic circadian clock.
Porphyromonas gingivalis triggers inflammatory responses in periodontal ligament cells by succinate-succinate dehydrogenase-HIF-1α axis.
Alisol A-24-acetate promotes glucose uptake via activation of AMPK in C2C12 myotubes.
Schnurri-3 regulates BMP9-induced osteogenic differentiation and angiogenesis of human amniotic mesenchymal stem cells through Runx2 and VEGF.
Calcium relieves fluoride-induced bone damage through the PI3K/AKT pathway.
Graphene Oxide Promotes Cancer Metastasis through Associating with Plasma Membrane To Promote TGF-β Signaling-Dependent Epithelial-Mesenchymal Transition.
GSPE alleviates renal fibrosis by inhibiting the activation of C3/ HMGB1/ TGF-β1 pathway.
An insertion mutation of ERBB2 enhances breast cancer cell growth and confers resistance to lapatinib through AKT signaling pathway.
miR-485 suppresses inflammation and proliferation of mesangial cells in an in vitro model of diabetic nephropathy by targeting NOX5.
FAM60A, increased by Helicobacter pylori, promotes proliferation and suppresses apoptosis of gastric cancer cells by targeting the PI3K/AKT pathway.
A protective role of renalase in diabetic nephropathy.
The Nuclear Matrix Protein SAFB Cooperates with Major Satellite RNAs to Stabilize Heterochromatin Architecture Partially through Phase Separation.
Effects of a natural PTP1B inhibitor from Rhodomela confervoides on the amelioration of fatty acid-induced insulin resistance in hepatocytes and hyperglycaemia in STZ-induced diabetic rats.
K562 cell-derived exosomes suppress the adhesive function of bone marrow mesenchymal stem cells via delivery of miR-711.
Fangchinoline derivatives induce cell cycle arrest and apoptosis in human leukemia cell lines via suppression of the PI3K/AKT and MAPK signaling pathway.
Microglia P2X4R-BDNF signalling contributes to central sensitization in a recurrent nitroglycerin-induced chronic migraine model.
DEF Cell-Derived Exosomal miR-148a-5p Promotes DTMUV Replication by Negative Regulating TLR3 Expression.
RETRACTED: Endogenous production of C-C motif chemokine ligand 2 by nasopharyngeal carcinoma cells drives radioresistance-associated metastasis.
Schizandrin B Mitigates Rifampicin-Induced Liver Injury by Inhibiting Endoplasmic Reticulum Stress.
Regulation of the firing activity by PKA-PKC-Src family kinases in cultured neurons of hypothalamic arcuate nucleus.
PITPNC1 fuels radioresistance of rectal cancer by inhibiting reactive oxygen species production.
Chronic toxicity of methamphetamine: Oxidative remodeling of pulmonary arteries.
Beta-Amyloid Increases the Expression Levels of Tid1 Responsible for Neuronal Cell Death and Amyloid Beta Production.
Association between different levels of lipid metabolism‑related enzymes and fatty acid synthase in Wilms' tumor.
BDNF-TrkB pathway mediates antidepressant-like roles of H(2) S in diabetic rats via promoting hippocampal autophagy.
Transcription factor RUNX2 regulates epithelial‑mesenchymal transition and progression in renal cell carcinomas.
Sirtuin 3 induces apoptosis and necroptosis by regulating mutant p53 expression in small‑cell lung cancer.
Visfatin Exerts Immunotherapeutic Effects in Lipopolysaccharide-Induced Acute Lung Injury in Murine Model.
Lactobacillus johnsonii L531 ameliorates enteritis via elimination of damaged mitochondria and suppression of SQSTM1-dependent mitophagy in a Salmonella infantis model of piglet diarrhea.
Berberine inhibits proliferation and migration of colorectal cancer cells by downregulation of GRP78.
RhoB is regulated by hypoxia and modulates metastasis in breast cancer.
Polychlorinated biphenyl quinone promotes macrophage polarization to CD163(+) cells through Nrf2 signaling pathway.
LncRNA HRCEG, regulated by HDAC1, inhibits cells proliferation and epithelial-mesenchymal-transition in gastric cancer.
Mitochondrial respiratory chain damage and mitochondrial fusion disorder are involved in liver dysfunction of fluoride-induced mice.
Effects of Starvation on Antioxidant-Related Signaling Molecules, Oxidative Stress, and Autophagy in Juvenile Chinese Perch Skeletal Muscle.
Involvement of neurotrophic signaling in doxorubicin-induced cardiotoxicity.
1,3-Dicaffeoylquinic acid targeting 14-3-3 tau suppresses human breast cancer cell proliferation and metastasis through IL6/JAK2/PI3K pathway.
Discovery of a first-in-class EZH2 selective degrader.
PDE9 inhibition promotes proliferation of neural stem cells via cGMP-PKG pathway following oxygen-glucose deprivation/reoxygenation injury in vitro.
Predictive Value of Pin1 in Cervical Low-Grade Squamous Intraepithelial Lesions and Inhibition of Pin1 Exerts Potent Anticancer Activity against Human Cervical Cancer.
Ferrostatin-1 mitigates cognitive impairment of epileptic rats by inhibiting P38 MAPK activation.
The Combination of Fasting, Acute Resistance Exercise, and Protein Ingestion Led to Different Responses of Autophagy Markers in Gastrocnemius and Liver Samples.
MicroRNA-377-3p alleviates IL-1β-caused chondrocyte apoptosis and cartilage degradation in osteoarthritis in part by downregulating ITGA6.
RNA Binding Protein RNPC1 Suppresses the Stemness of Human Endometrial Cancer Cells via Stabilizing MST1/2 mRNA.
Targeting UBE4A Revives Viperin Protein in Epithelium to Enhance Host Antiviral Defense.
Polyphyllin VII attenuated RANKL-induced osteoclast differentiation via inhibiting of TRAF6/c-Src/PI3K pathway and ROS production.
GRWD1 promotes cell proliferation and migration in non-small cell lung cancer by activating the Notch pathway.
Network Pharmacology-Based Prediction and Verification of Qingluo Tongbi Formula to Reduce Liver Toxicity of Tripterygium wilfordii via UGT2B7 in Endoplasmic Reticulum.
PRL/microRNA-183/IRS1 Pathway Regulates Milk Fat Metabolism in Cow Mammary Epithelial Cells.
Sustained delivery of PlGF-2(123-144*)-fused BMP2-related peptide P28 from small intestinal submucosa/polylactic acid scaffold material for bone tissue regeneration.
Doublecortin undergo nucleocytoplasmic transport via the RanGTPase signaling to promote glioma progression.
Curcumin Protects Human Trophoblast HTR8/SVneo Cells from H(2)O(2)-Induced Oxidative Stress by Activating Nrf2 Signaling Pathway.
Protective effect of resveratrol on obesity-related osteoarthritis via alleviating JAK2/STAT3 signaling pathway is independent of SOCS3.
PTP1B promotes macrophage activation by regulating the NF-κB pathway in alcoholic liver injury.
Silencing of DsbA-L gene impairs the PPARγ agonist function of improving insulin resistance in a high-glucose cell model.
SUMOylation of Pdia3 exacerbates proinsulin misfolding and ER stress in pancreatic beta cells.
LXA4 protects against hypoxic-ischemic damage in neonatal rats by reducing the inflammatory response via the IκB/NF-κB pathway.
Annexin A3 upregulates the infiltrated neutrophil-lymphocyte ratio to remodel the immune microenvironment in hepatocellular carcinoma.
Angiopoietin-like protein 4 promotes very-low-density lipoprotein assembly and secretion in bovine hepatocytes in vitro.
Quercetin alleviates neonatal hypoxic-ischemic brain injury by inhibiting microglia-derived oxidative stress and TLR4-mediated inflammation.
Knockdown of eukaryotic translation initiation factor 5A2 enhances the therapeutic efficiency of doxorubicin in hepatocellular carcinoma cells by triggering lethal autophagy.
Nobiletin Ameliorates NLRP3 Inflammasome-Mediated Inflammation Through Promoting Autophagy via the AMPK Pathway.
An antiviral drug-resistant mutant of hepatitis B virus with high replication capacity in association with a large in-frame deletion in the preS1 region of viral surface gene.
Intratunical injection of human urine-derived stem cells derived exosomes prevents fibrosis and improves erectile function in a rat model of Peyronie's disease.
MMP7 damages the integrity of the renal tubule epithelium by activating MMP2/9 during ischemia-reperfusion injury.
Down-Regulated CUEDC2 Increases GDNF Expression by Stabilizing CREB Through Reducing Its Ubiquitination in Glioma.
Aberrant expression of miRNA-192-5p contributes to N,N-dimethylformamide-induced hepatic apoptosis.
Histone demethylase JHDM2A regulates H3K9 dimethylation in response to arsenic-induced DNA damage and repair in normal human liver cells.
Inhibition of ACSL4 attenuates ferroptotic damage after pulmonary ischemia-reperfusion.
PFOS-induced placental cell growth inhibition is partially mediated by lncRNA H19 through interacting with miR-19a and miR-19b.
Molecular identification, tissue distribution and in vitro functional analysis of growth hormone and its receptors in red-spotted grouper (Epinephelus akaara).
Inhibition of CACNA1H can alleviate endoplasmic reticulum stress and reduce myocardial cell apoptosis caused by myocardial infarction.
FABP4 inhibitor attenuates inflammation and endoplasmic reticulum stress of islet in leptin receptor knockout rats.
Polarization of ADAM17-driven EGFR signalling in electric field-guided collective migration of epidermal sheets.
The proinflammatory cytokines IL-1β and TNF-α modulate corneal epithelial wound healing through p16(Ink4a) suppressing STAT3 activity.
miR-448-3p alleviates diabetic vascular dysfunction by inhibiting endothelial-mesenchymal transition through DPP-4 dysregulation.
Inhibition of p38 MAPK regulates epileptic severity by decreasing expression levels of A1R and ENT1.
Effect of TFAM on ATP content in tachypacing primary cultured cardiomyocytes and atrial fibrillation patients.
IGFBP‑rP1‑silencing promotes hypoxia‑induced angiogenic potential of choroidal endothelial cells via the RAF/MEK/ERK signaling pathway.
Pseudolaric acid B induces apoptosis in human rhabdomyosarcoma RD cells.
A Combination of BRD4 and HDAC3 Inhibitors Synergistically Suppresses Glioma Stem Cell Growth by Blocking GLI1/IL6/STAT3 Signaling Axis.
Resveratrol improves meat quality, muscular antioxidant capacity, lipid metabolism and fiber type composition of intrauterine growth retarded pigs.
Polymethoxyflavones from citrus inhibited gastric cancer cell proliferation through inducing apoptosis by upregulating RARβ, both in vitro and in vivo.
Cannabinoid receptor subtype influence on neuritogenesis in human SH-SY5Y cells.
Andrographolide exerts anti-inflammatory effects in Mycobacterium tuberculosis-infected macrophages by regulating the Notch1/Akt/NF-κB axis.
Structural and Functional Characterization of Host FHL1 Protein Interaction with Hypervariable Domain of Chikungunya Virus nsP3 Protein.
β-Elemene enhances radiosensitivity in non-small-cell lung cancer by inhibiting epithelial-mesenchymal transition and cancer stem cell traits via Prx-1/NF-kB/iNOS signaling pathway.
Condensation of Rubisco into a proto-pyrenoid in higher plant chloroplasts.
Exploration of the Effects of Substrate Stiffness on Biological Responses of Neural Cells and Their Mechanisms.
circ_2858 Helps Blood-Brain Barrier Disruption by Increasing VEGFA via Sponging miR-93-5p during Escherichia coli Meningitis.
Metabotropic glutamate receptor 5 regulates synaptic plasticity in a chronic migraine rat model through the PKC/NR2B signal.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein inhibits type I and III interferon production by targeting RIG-I/MDA-5 signaling.
TRIM24 promotes stemness and invasiveness of glioblastoma cells via activating Sox2 expression.
RIPK1 Distinctly Regulates Yersinia-Induced Inflammatory Cell Death, PANoptosis.
Ubiquitination of RIPK1 regulates its activation mediated by TNFR1 and TLRs signaling in distinct manners.
Exploring the mechanism of cisplatin resistance by transcriptome sequencing and reversing the chemoresistance by autophagy inhibition in small cell lung cancer.
Podocyte-derived extracellular vesicles mediate renal proximal tubule cells dedifferentiation via microRNA-221 in diabetic nephropathy.
PhospholipaseCγ1/calcium-dependent membranous localization of Gsdmd-N drives endothelial pyroptosis, contributing to lipopolysaccharide-induced fatal outcome.
Effects of taraxasterol against ethanol and high-fat diet-induced liver injury by regulating TLR4/MyD88/NF-κB and Nrf2/HO-1 signaling pathways.
NPY stimulates cholesterol synthesis acutely by activating the SREBP2-HMGCR pathway through the Y1 and Y5 receptors in murine hepatocytes.
Prostaglandin I2 mediates weak vasodilatation in human placental microvessels.
HOTAIR promotes paclitaxel resistance by regulating CHEK1 in ovarian cancer.
Ginsenoside Rk3 alleviated DSS-induced ulcerative colitis by protecting colon barrier and inhibiting NLRP3 inflammasome pathway.
Metformin inhibits extracellular matrix accumulation, inflammation and proliferation of mesangial cells in diabetic nephropathy by regulating H19/miR-143-3p/TGF-β1 axis.
GOLPH3 Regulates Exosome miRNA Secretion in Glioma Cells.
Metabolomic profiling reveals similar cytotoxic effects and protective functions of quercetin during deoxynivalenol- and 15-acetyl deoxynivalenol-induced cell apoptosis.
All-Trans Retinoic Acid Exerts Neuroprotective Effects in Amyotrophic Lateral Sclerosis-Like Tg (SOD1*G93A)1Gur Mice.
Exopolysaccharide from Cryptococcus heimaeyensis S20 induces autophagic cell death in non-small cell lung cancer cells via ROS/p38 and ROS/ERK signalling.
Role of Zinc Sulphate in Immune Regulation in Artemisia annua Pollen-challenged P815 Mastocytoma Cells.
Exogenous spermine attenuates myocardial fibrosis in diabetic cardiomyopathy by inhibiting endoplasmic reticulum stress and the canonical Wnt signaling pathway.
Setosphapyrone C and D accelerate macrophages cholesterol efflux by promoting LXRα/ABCA1 pathway.
Thymidine phosphorylase promotes angiogenesis and tumour growth in intrahepatic cholangiocarcinoma.
Downregulation of miR-140-5p affects the pathogenesis of HSCR by targeting EGR2.
Inhibition of the facilitative sugar transporters (GLUTs) by tea extracts and catechins.
Lnc00462717 regulates the permeability of the blood-brain tumor barrier through interaction with PTBP1 to inhibit the miR-186-5p/Occludin signaling pathway.
USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylation.
Pseudorabies virus infection inhibits stress granules formation via dephosphorylating eIF2α.
Protective effect of exogenous hydrogen sulfide on diaphragm muscle fibrosis in streptozotocin-induced diabetic rats.
Cell cycle exit during bortezomib-induced osteogenic differentiation of mesenchymal stem cells was mediated by Xbp1s-upregulated p21(Cip1) and p27(Kip1).
Salvianic acid A alleviates chronic alcoholic liver disease by inhibiting HMGB1 translocation via down-regulating BRD4.
Septin4 regulates endoplasmic reticulum stress and apoptosis in melatonin‑induced osteoblasts.
Overexpression of negative regulator of ubiquitin-like proteins 1 (NUB1) inhibits proliferation and invasion of gastric cancer cells through upregulation of p27Kip1 and inhibition of epithelial-mesenchymal transition.
Overexpression of B7-H4 promotes renal cell carcinoma progression by recruiting tumor-associated neutrophils via upregulation of CXCL8.
Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated β-catenin pathway and EMT in colorectal cancer.
Catalase is required for peroxisome maintenance during adipogenesis.
Targeting G6PD reverses paclitaxel resistance in ovarian cancer by suppressing GSTP1.
Localization of ZIP14 and ZIP8 in HIBCPP Cells.
Reelin Promotes Cisplatin Resistance by Induction of Epithelial-Mesenchymal Transition via p38/GSK3β/Snail Signaling in Non-Small Cell Lung Cancer.
STIM1-mediated calcium influx controls antifungal immunity and the metabolic function of non-pathogenic Th17 cells.
Selective Translation of Cell Fate Regulators Mediates Tolerance to Broad Oncogenic Stress.
Development of a Cationic Amphiphilic Helical Peptidomimetic (B18L) As A Novel Anti-Cancer Drug Lead.
Hippuric Acid Promotes Renal Fibrosis by Disrupting Redox Homeostasis via Facilitation of NRF2-KEAP1-CUL3 Interactions in Chronic Kidney Disease.
Cotargeting of Mitochondrial Complex I and Bcl-2 Shows Antileukemic Activity against Acute Myeloid Leukemia Cells Reliant on Oxidative Phosphorylation.
α-Mangostin, a Dietary Xanthone, Exerts Protective Effects on Cisplatin-Induced Renal Injury via PI3K/Akt and JNK Signaling Pathways in HEK293 Cells.
Tetrandrine enhances glucocorticoid receptor translocation possibly via inhibition of P-glycoprotein in daunorubicin-resistant human T lymphoblastoid leukemia cells.
Bcl2 inhibitor ABT737 reverses the Warburg effect via the Sirt3-HIF1α axis to promote oxidative stress-induced apoptosis in ovarian cancer cells.
Lactobacillus johnsonii L531 Ameliorates Escherichia coli-Induced Cell Damage via Inhibiting NLRP3 Inflammasome Activity and Promoting ATG5/ATG16L1-Mediated Autophagy in Porcine Mammary Epithelial Cells.
Plakoglobin is involved in cytoskeletal rearrangement of podocytes under the regulation of UCH-L1.
Flavagline synthetic derivative induces senescence in glioblastoma cancer cells without being toxic to healthy astrocytes.
Acetylation of Cytidine Residues Boosts HIV-1 Gene Expression by Increasing Viral RNA Stability.
Cultivation of Hair Matrix Cells from Cashmere Goat Skins and Exemplified Applications.
The Small Molecule P7C3-A20 Exerts Neuroprotective Effects in a Hypoxic-ischemic Encephalopathy Model via Activation of PI3K/AKT/GSK3β Signaling.
TMT-based proteomics analysis reveals the protective effects of Xuefu Zhuyu decoction in a rat model of traumatic brain injury.
Lignans from Schisandra chinensis ameliorate alcohol and CCl(4)-induced long-term liver injury and reduce hepatocellular degeneration via blocking ETBR.
Role of ion channels in chronic intermittent hypoxia-induced atrial remodeling in rats.
TLR4 knockout upregulates the expression of Mfn2 and PGC-1α in a high-fat diet and ischemia-reperfusion mice model of liver injury.
Comparative analysis of two brine shrimps revealed differential expression pattern and functional characterization of CK2α under bacterial stimulation from different geographical distribution.
Fangjihuangqi Decoction inhibits MDA-MB-231 cell invasion in vitro and decreases tumor growth and metastasis in triple-negative breast cancer xenografts tumor zebrafish model.
Berberine combined with cyclosporine A alleviates acute graft-versus-host disease in murine models.
Long non-coding RNA LOC100133669 promotes cell proliferation in oesophageal squamous cell carcinoma.
Retinoid X receptor α (RXRα)-mediated erythroid-2-related factor-2 (NRF2) inactivation contributes to N,N-dimethylformamide (DMF)-induced oxidative stress in HL-7702 and HuH6 cells.
The Potential Role of PKA/CREB Signaling Pathway Concerned with Gastrodin Administration on Methamphetamine-Induced Conditioned Place Preference Rats and SH-SY5Y Cell Line.
Virus analog decreases estradiol secretion in FSH-treated human ovarian granulosa cells.
The deletion of mutant SOD1 via CRISPR/Cas9/sgRNA prolongs survival in an amyotrophic lateral sclerosis mouse model.
MiR-129-5p protects against myocardial ischemia-reperfusion injury via targeting HMGB1.
Targeting STAT3 enhances NDV-induced immunogenic cell death in prostate cancer cells.
GLL398, an oral selective estrogen receptor degrader (SERD), blocks tumor growth in xenograft breast cancer models.
IL-29 promoted obesity-induced inflammation and insulin resistance.
NEK2 induces autophagy-mediated bortezomib resistance by stabilizing Beclin-1 in multiple myeloma.
A novel Sprouty4-ERK1/2-Wnt/β-catenin regulatory loop in marrow stromal progenitor cells controls osteogenic and adipogenic differentiation.
Myxovirus resistance (Mx) gene and its differential expression regulated by three type I and two type II IFNs in mandarin fish, Siniperca chuatsi.
AKT but not MYC promotes reactive oxygen species-mediated cell death in oxidative culture.
p53-mediated control of aspartate-asparagine homeostasis dictates LKB1 activity and modulates cell survival.
A Combination of Formic Acid and Monolaurin Attenuates Enterotoxigenic Escherichia coli Induced Intestinal Inflammation in Piglets by Inhibiting the NF-κB/MAPK Pathways with Modulation of Gut Microbiota.
Synergistic Neuroprotective Effect of Endogenously-Produced Hydroxytyrosol and Synaptic Vesicle Proteins on Pheochromocytoma Cell Line Against Salsolinol.
Interaction between PHB2 and Enterovirus A71 VP1 Induces Autophagy and Affects EV-A71 Infection.
Anti-neuroinflammatory effects of dimethylaminomylide (DMAMCL, i.e., ACT001) are associated with attenuating the NLRP3 inflammasome in MPTP-induced Parkinson disease in mice.
MicroRNA-574-5p in gastric cancer cells promotes angiogenesis by targeting protein tyrosine phosphatase non-receptor type 3 (PTPN3).
Effect of fluoride on osteocyte-driven osteoclastic differentiation.
Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense.
Decreased ZNF750 promotes angiogenesis in a paracrine manner via activating DANCR/miR-4707-3p/FOXC2 axis in esophageal squamous cell carcinoma.
Cold atmospheric plasma induces GSDME-dependent pyroptotic signaling pathway via ROS generation in tumor cells.
4β-Hydroxywithanolide E from Goldenberry (Whole Fruits of Physalis peruviana L.) as a Promising Agent against Chronic Obstructive Pulmonary Disease.
HIF-1β Positively Regulates NF-κB Activity via Direct Control of TRAF6.
Maternal curcumin supplementation ameliorates placental function and fetal growth in mice with intrauterine growth retardation†.
Pathogenic Variants in CEP85L Cause Sporadic and Familial Posterior Predominant Lissencephaly.
Soluble epoxide hydrolase inhibitor protects against blood-brain barrier dysfunction in a mouse model of type 2 diabetes via the AMPK/HO-1 pathway.
AcMNPV PKIP is required for hyperexpression of very late genes and involved in the hyperphosphorylation of the viral basic protein P6.9.
Circadian clock gene Clock is involved in the pathogenesis of preeclampsia through hypoxia.
STIM2 knockdown protects against ischemia/reperfusion injury through reducing mitochondrial calcium overload and preserving mitochondrial function.
The SCF(β-TrCP) E3 Ubiquitin Ligase Regulates Immune Receptor Signaling by Targeting the Negative Regulatory Protein TIPE2.
Physicochemical characterization of polysaccharide from the leaf of Dendrobium officinale and effect on LPS induced damage in GES-1 cell.
Trehalose attenuates renal ischemia-reperfusion injury by enhancing autophagy and inhibiting oxidative stress and inflammation.
Localized injection of miRNA-21-enriched extracellular vesicles effectively restores cardiac function after myocardial infarction.
HSF2 regulates aerobic glycolysis by suppression of FBP1 in hepatocellular carcinoma.
Oncogenic MSH6-CXCR4-TGFB1 Feedback Loop: A Novel Therapeutic Target of Photothermal Therapy in Glioblastoma Multiforme.
Targeting mitochondrial dynamics by regulating Mfn2 for therapeutic intervention in diabetic cardiomyopathy.
Triptolide Induces Glioma Cell Autophagy and Apoptosis via Upregulating the ROS/JNK and Downregulating the Akt/mTOR Signaling Pathways.
Identification of RE1-Silencing Transcription Factor as a Promoter of Metastasis in Pancreatic Cancer.
Inhibition of oxidative stress by testosterone improves synaptic plasticity in senescence accelerated mice.
Evidence for interaction of the NLRP3 inflammasome and Bruton's tyrosine kinase in tumor-associated macrophages: implications for myeloid cell production of interleukin-1beta.
Bergenin Ameliorates MPTP-Induced Parkinson's Disease by Activating PI3K/Akt Signaling Pathway.
aFGF Promotes Neurite Growth by Regulating GSK3β-CRMP2 Signaling Pathway in Cortical Neurons Damaged by Amyloid-β.
Synergetic Inhibition of Human Colorectal Cancer Cells by Combining Polyyne-Enriched Fraction from Oplopanax elatus and Irinotecan.
AAV9-Mediated Cdk5 Inhibitory Peptide Reduces Hyperphosphorylated Tau and Inflammation and Ameliorates Behavioral Changes Caused by Overexpression of p25 in the Brain.
MiR-223-3p Alleviates Vascular Endothelial Injury by Targeting IL6ST in Kawasaki Disease.
Loss of the Golgi Matrix Protein 130 Cause Aberrant IgA1 Glycosylation in IgA Nephropathy.
Chemo-Preventive Potential of Falcarindiol-Enriched Fraction from Oplopanax elatus on Colorectal Cancer Interfered by Human Gut Microbiota.
Cinobufagin Promotes Cell Cycle Arrest and Apoptosis to Block Human Esophageal Squamous Cell Carcinoma Cells Growth via the p73 Signalling Pathway.
Loss of Mitochondrial DNA by Gemcitabine Triggers Mitophagy and Cell Death.
RNA-seq analysis of PHD and VHL inhibitors reveals differences and similarities to the hypoxia response.
The Role of Nrf2 Signaling Pathway in Eucommia ulmoides Flavones Regulating Oxidative Stress in the Intestine of Piglets.
Dexmedetomidine Attenuates Orthotopic Liver Transplantation-Induced Acute Gut Injury via α (2)-Adrenergic Receptor-Dependent Suppression of Oxidative Stress.
Paneth Cell Ablation Aggravates Pancreatic and Intestinal Injuries in a Rat Model of Acute Necrotizing Pancreatitis after Normal and High-Fat Diet.
Palmitic Acid Induces MicroRNA-221 Expression to Decrease Glucose Uptake in HepG2 Cells via the PI3K/AKT/GLUT4 Pathway.
Tetrandrine-Induced Autophagy in MDA-MB-231 Triple-Negative Breast Cancer Cell through the Inhibition of PI3K/AKT/mTOR Signaling.
N-n-Butyl Haloperidol Iodide Ameliorates Oxidative Stress in Mitochondria Induced by Hypoxia/Reoxygenation through the Mitochondrial c-Jun N-Terminal Kinase/Sab/Src/Reactive Oxygen Species Pathway in H9c2 Cells.
Oral Administration of Lactobacillus delbrueckii during the Suckling Phase Improves Antioxidant Activities and Immune Responses after the Weaning Event in a Piglet Model.
Minocycline Protects against Rotenone-Induced Neurotoxicity Correlating with Upregulation of Nurr1 in a Parkinson's Disease Rat Model.
Phosphocreatine Improves Cardiac Dysfunction by Normalizing Mitochondrial Respiratory Function through JAK2/STAT3 Signaling Pathway In Vivo and In Vitro.
CD133 Is Associated with Increased Melanoma Cell Survival after Multikinase Inhibition.
CTGF Attenuates Tendon-Derived Stem/Progenitor Cell Aging.
Reactive Oxygen Species Are Involved in the Development of Gastric Cancer and Gastric Cancer-Related Depression through ABL1-Mediated Inflammation Signaling Pathway.
Purple Sweet Potato Color Attenuates Kidney Damage by Blocking VEGFR2/ROS/NLRP3 Signaling in High-Fat Diet-Treated Mice.
Nicorandil Attenuates LPS-Induced Acute Lung Injury by Pulmonary Endothelial Cell Protection via NF-κB and MAPK Pathways.
Shuangyu Tiaozhi Granule Attenuates Hypercholesterolemia through the Reduction of Cholesterol Synthesis in Rat Fed a High Cholesterol Diet.
Prevention of Huntington's Disease-Like Behavioral Deficits in R6/1 Mouse by Tolfenamic Acid Is Associated with Decreases in Mutant Huntingtin and Oxidative Stress.
Bu Shen Zhu Yun Decoction Improves Endometrial Receptivity via VEGFR-2-Mediated Angiogenesis.
Yiqihuoxue Formula Activates Autophagy and Offers Renoprotection in a Rat Model of Adenine-Induced Kidney Disease.
Curcumin and Curcumol Inhibit NF-κB and TGF-β (1)/Smads Signaling Pathways in CSE-Treated RAW246.7 Cells.
Astragalus Membranaceus Treatment Protects Raw264.7 Cells from Influenza Virus by Regulating G1 Phase and the TLR3-Mediated Signaling Pathway.
Salvianolic Acid A Protects the Kidney against Oxidative Stress by Activating the Akt/GSK-3β/Nrf2 Signaling Pathway and Inhibiting the NF-κB Signaling Pathway in 5/6 Nephrectomized Rats.
Stem Cells from Human Exfoliated Deciduous Teeth Ameliorate Diabetic Nephropathy In Vivo and In Vitro by Inhibiting Advanced Glycation End Product-Activated Epithelial-Mesenchymal Transition.
Leukemia Inhibitory Factor Receptor Is Involved in Apoptosis in Rat Astrocytes Exposed to Oxygen-Glucose Deprivation.
Astragaloside IV Suppresses High Glucose-Induced NLRP3 Inflammasome Activation by Inhibiting TLR4/NF-κB and CaSR.
miR-100-3p inhibits cell proliferation and induces apoptosis in human gastric cancer through targeting to BMPR2.
SSRP1 influences colorectal cancer cell growth and apoptosis via the AKT pathway.
Fucoidan prevent murine autoimmune diabetes via suppression TLR4-signaling pathways, regulation DC/Treg induced immune tolerance and improving gut microecology.
CXXC5 Mediates P. gingivalis-suppressed Cementoblast Functions Partially via MAPK Signaling Network.
Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts.
SPSB2 inhibits hepatitis C virus replication by targeting NS5A for ubiquitination and degradation.
Resveratrol induced premature senescence and inhibited epithelial-mesenchymal transition of cancer cells via induction of tumor suppressor Rad9.
The Pseudogene PTTG3P Promotes Cell Migration and Invasion in Esophageal Squamous Cell Carcinoma.
Synergism of cisplatin-oleanolic acid co-loaded calcium carbonate nanoparticles on hepatocellular carcinoma cells for enhanced apoptosis and reduced hepatotoxicity.
Treatment With Liraglutide Exerts Neuroprotection After Hypoxic-Ischemic Brain Injury in Neonatal Rats via the PI3K/AKT/GSK3β Pathway.
Overexpression of CX3CR1 in Adipose-Derived Stem Cells Promotes Cell Migration and Functional Recovery After Experimental Intracerebral Hemorrhage.
Arsenic sulfide induces miR-4665-3p to inhibit gastric cancer cell invasion and migration.
Hydrogen Sulfide Attenuates β2-Microglobulin-Induced Cognitive Dysfunction: Involving Recovery of Hippocampal Autophagic Flux.
Necrostatin-1 Ameliorates Peripheral Nerve Injury-Induced Neuropathic Pain by Inhibiting the RIP1/RIP3 Pathway.
The Neuroprotection of KIBRA in Promoting Neuron Survival and Against Amyloid β-Induced Apoptosis.
SUMOylation and deacetylation affect NF-κB p65 activity induced by high glucose in human lens epithelial cells.
Gatifloxacin inducing apoptosis of stromal fibroblasts through cross-talk between caspase-dependent extrinsic and intrinsic pathways.
Expression Of BMP7 In Ovarian Cancer And Biological Effect Of BMP7 Knockdown On Ovarian Cancer Cells.
MicroRNA-765 sensitizes osteosarcoma cells to cisplatin via downregulating APE1 expression.
LAPTM4B knockdown increases the radiosensitivity of EGFR-overexpressing radioresistant nasopharyngeal cancer cells by inhibiting autophagy.
β-elemene inhibits radiation and hypoxia-induced macrophages infiltration via Prx-1/NF-κB/HIF-1α signaling pathway.
Exosomal Tenascin-c induces proliferation and invasion of pancreatic cancer cells by WNT signaling.
Multiple Functions of KBP in Neural Development Underlie Brain Anomalies in Goldberg-Shprintzen Syndrome.
Dichloroacetic acid upregulates apoptosis of ovarian cancer cells by regulating mitochondrial function.
miR-492 Promotes Cancer Progression by Targeting GJB4 and Is a Novel Biomarker for Bladder Cancer.
miR-509-5p Downregulation Is Associated With Male Infertility And Acts As A Suppressor In Testicular Germ Cell Tumor Cells Through Targeting MDM2.
Escin protects against acetaminophen-induced liver injury in mice via attenuating inflammatory response and inhibiting ERK signaling pathway.
MiR-302a-5p suppresses cell proliferation and invasion in non-small cell lung carcinoma by targeting ITGA6.
VASN promotes YAP/TAZ and EMT pathway in thyroid carcinogenesis in vitro.
Overexpression of CBX2 in breast cancer promotes tumor progression through the PI3K/AKT signaling pathway.
BPTF cooperates with p50 NF-κB to promote COX-2 expression and tumor cell growth in lung cancer.
Clinical roles of miR-136-5p and its target metadherin in thyroid carcinoma.
Downregulation of angiopoietin-like protein 2 inhibits cementoblast differentiation partially by activating the ERK1/2 signaling pathway.
ADAR1 may be involved in the proliferation of acute myeloid leukemia cells via regulation of the Wnt pathway.
Overexpressed PKMYT1 promotes tumor progression and associates with poor survival in esophageal squamous cell carcinoma.
HIF1α/miR-520a-3p/AKT1/mTOR Feedback Promotes The Proliferation And Glycolysis Of Gastric Cancer Cells.
STIP1 Regulates Proliferation and Migration of Lung Adenocarcinoma Through JAK2/STAT3 Signaling Pathway.
Inhibition of RNA-Binding Protein Musashi-1 Suppresses Malignant Properties and Reverses Paclitaxel Resistance in Ovarian Carcinoma.
CLEC4M is associated with poor prognosis and promotes cisplatin resistance in NSCLC patients.
Methylation of SLFN11 promotes gastric cancer growth and increases gastric cancer cell resistance to cisplatin.
EP300 as an oncogene correlates with poor prognosis in esophageal squamous carcinoma.
8-bromo-7-methoxychrysin targets NF-κB and FoxM1 to inhibit lung cancer stem cells induced by pro-inflammatory factors.
An NF90/long noncoding RNA-LET/miR-548k feedback amplification loop controls esophageal squamous cell carcinoma progression.
Verteporfin suppresses the proliferation, epithelial-mesenchymal transition and stemness of head and neck squamous carcinoma cells via inhibiting YAP1.
ITRAQ-Based Proteomics Analysis Reveals the Effect of Neoliensinine on KCl-Induced Vascular Smooth Muscle Contraction by Inhibiting Regulatory Light Chain Phosphorylation.
Discovery of N-(2-Aminophenyl)-4-(bis(2-chloroethyl)amino)Benzamide as a Potent Histone Deacetylase Inhibitor.
A Novel Regulatory Circuit "C/EBPα/miR-20a-5p/TOB2" Regulates Adipogenesis and Lipogenesis.
Effects of Exercise Training on the Autophagy-Related Muscular Proteins Expression in Ovariectomized Rats.
Irbesartan Ameliorates Lipid Deposition by Enhancing Autophagy via PKC/AMPK/ULK1 Axis in Free Fatty Acid Induced Hepatocytes.
Fish Autophagy Protein 5 Exerts Negative Regulation on Antiviral Immune Response Against Iridovirus and Nodavirus.
A Novel Postbiotic From Lactobacillus rhamnosus GG With a Beneficial Effect on Intestinal Barrier Function.
An improved Tet-on system in microRNA overexpression and CRISPR/Cas9-mediated gene editing.
Identification of a Novel Bcl-2 Inhibitor by Ligand-Based Screening and Investigation of Its Anti-cancer Effect on Human Breast Cancer Cells.
Prepartum body conditions affect insulin signaling pathways in postpartum adipose tissues in transition dairy cows.
Da-Bu-Yin-Wan and Qian-Zheng-San Ameliorate Mitochondrial Dynamics in the Parkinson's Disease Cell Model Induced by MPP().
The Involvement of Renin-Angiotensin System in Lipopolysaccharide-Induced Behavioral Changes, Neuroinflammation, and Disturbed Insulin Signaling.
Epstein-Barr Virus Nuclear Antigen 1 Recruits Cyclophilin A to Facilitate the Replication of Viral DNA Genome.
Dengue Virus Infection Activates Interleukin-1β to Induce Tissue Injury and Vascular Leakage.
Hypertensive Rats Treated Chronically With N(ω)-Nitro-L-Arginine Methyl Ester (L-NAME) Induced Disorder of Hepatic Fatty Acid Metabolism and Intestinal Pathophysiology.
Cathelicidin-WA Facilitated Intestinal Fatty Acid Absorption Through Enhancing PPAR-γ Dependent Barrier Function.
The Capsid Protein VP1 of Coxsackievirus B Induces Cell Cycle Arrest by Up-Regulating Heat Shock Protein 70.
LncRNA LUCRC Regulates Colorectal Cancer Cell Growth and Tumorigenesis by Targeting Endoplasmic Reticulum Stress Response.
Ghrelin Attenuates Neuroinflammation and Demyelination in Experimental Autoimmune Encephalomyelitis Involving NLRP3 Inflammasome Signaling Pathway and Pyroptosis.
An Improved Enzyme-Linked Focus Formation Assay Revealed Baloxavir Acid as a Potential Antiviral Therapeutic Against Hantavirus Infection.
LPS Induces Preeclampsia-Like Phenotype in Rats and HTR8/SVneo Cells Dysfunction Through TLR4/p38 MAPK Pathway.
Sorghum Phenolics Inhibits Inflammasomes in Lipopolysaccharide (LPS)-Primed and Adenosine Triphosphate (ATP)-Activated Macrophages.
Functional evidence for a de novo mutation in WDR45 leading to BPAN in a Chinese girl.
Aerobic Exercise Improves Synaptic-Related Proteins of Diabetic Rats by Inhibiting FOXO1/NF-κB/NLRP3 Inflammatory Signaling Pathway and Ameliorating PI3K/Akt Insulin Signaling Pathway.
Comparison of the Effects of Green and Black Tea Extracts on Na(+) /K(+) -ATPase Activity in Intestine of Type 1 and Type 2 Diabetic Mice.
Mechanosensitive ion channel Piezo1 promotes prostate cancer development through the activation of the Akt/mTOR pathway and acceleration of cell cycle.
MicroRNA-191 promotes hepatocellular carcinoma cell proliferation by has_circ_0000204/miR-191/KLF6 axis.
Cardiac troponin I autoantibody induces myocardial dysfunction by PTEN signaling activation.
DEPDC1 drives hepatocellular carcinoma cell proliferation, invasion and angiogenesis by regulating the CCL20/CCR6 signaling pathway.
Eukaryotic elongation factor-2 kinase regulates the cross-talk between autophagy and pyroptosis in doxorubicin-treated human melanoma cells in vitro.
The Functional Polymorphism R129W in the BVES Gene Is Associated with Sporadic Tetralogy of Fallot in the Han Chinese Population.
Ursolic acid suppresses the invasive potential of colorectal cancer cells by regulating the TGF-β1/ZEB1/miR-200c signaling pathway.
2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone induced apoptosis and G1 cell cycle arrest through PI3K/AKT pathway in BEL-7402/5-FU cells.
HOXA11-AS regulates JAK-STAT pathway by miR-15a-3p/STAT3 axis to promote the growth and metastasis in liver cancer.
SARI attenuates colon inflammation by promoting STAT1 degradation in intestinal epithelial cells.
Induction of Nrf2 pathway by Dendrobium nobile Lindl. alkaloids protects against carbon tetrachloride induced acute liver injury.
A hidden human proteome encoded by 'non-coding' genes.
LINC01123, a c-Myc-activated long non-coding RNA, promotes proliferation and aerobic glycolysis of non-small cell lung cancer through miR-199a-5p/c-Myc axis.
CDK5-dependent phosphorylation and nuclear translocation of TRIM59 promotes macroH2A1 ubiquitination and tumorigenicity.
Applying vibration in early postmenopausal osteoporosis promotes osteogenic differentiation of bone marrow-derived mesenchymal stem cells and suppresses postmenopausal osteoporosis progression.
Fine particulate matters induce apoptosis via the ATM/P53/CDK2 and mitochondria apoptosis pathway triggered by oxidative stress in rat and GC-2spd cell.
NRF2-dependent gene expression promotes ciliogenesis and Hedgehog signaling.
MiR-143-3p directly targets GLUT9 to reduce uric acid reabsorption and inflammatory response of renal tubular epithelial cells.
Kinsenoside ameliorates intervertebral disc degeneration through the activation of AKT-ERK1/2-Nrf2 signaling pathway.
Accelerated Metabolite Levels of Aerobic Glycolysis and the Pentose Phosphate Pathway Are Required for Efficient Replication of Infectious Spleen and Kidney Necrosis Virus in Chinese Perch Brain Cells.
Long non-coding RNA, HOTAIRM1, promotes glioma malignancy by forming a ceRNA network.
Maltol (3-Hydroxy-2-methyl-4-pyrone) Slows d-Galactose-Induced Brain Aging Process by Damping the Nrf2/HO-1-Mediated Oxidative Stress in Mice.
Exosomes derived from cardiac progenitor cells attenuate CVB3-induced apoptosis via abrogating the proliferation of CVB3 and modulating the mTOR signaling pathways.
Bisdemethoxycurcumin Protection of Cardiomyocyte Mainly Depends on Nrf2/HO-1 Activation Mediated by the PI3K/AKT Pathway.
Regulatory effect of a Chinese herbal medicine formula on non-alcoholic fatty liver disease.
Artocarmitin B enhances intracellular antioxidant capacity via activation of Nrf2 signaling pathway in human lung epithelial cells.
Tetrandrine and cepharanthine induce apoptosis through caspase cascade regulation, cell cycle arrest, MAPK activation and PI3K/Akt/mTOR signal modification in glucocorticoid resistant human leukemia Jurkat T cells.
Astragaloside IV protects against hyperglycemia-induced vascular endothelial dysfunction by inhibiting oxidative stress and Calpain-1 activation.
The protective effects of Ghrelin/GHSR on hippocampal neurogenesis in CUMS mice.
Grouper Atg12 negatively regulates the antiviral immune response against Singapore grouper iridovirus (SGIV) infection.
MicroRNA-182-3p negatively regulates cytokines expression by targeting TLR5M in orange-spotted grouper, Epinephelus coioides.
Naringin mitigates myocardial strain and the inflammatory response in sepsis-induced myocardial dysfunction through regulation of PI3K/AKT/NF-κB pathway.
Rhein inhibits ATP-triggered inflammatory responses in rheumatoid rat fibroblast-like synoviocytes.
SIRT1-regulated HMGB1 release is partially involved in TLR4 signal transduction: A possible anti-neuroinflammatory mechanism of resveratrol in neonatal hypoxic-ischemic brain injury.
USP22 Deubiquitinates CD274 to Suppress Anticancer Immunity.
Overexpression of Limb-Bud and Heart (LBH) promotes angiogenesis in human glioma via VEGFA-mediated ERK signalling under hypoxia.
MiR-26a promotes fracture healing of nonunion rats possibly by targeting SOSTDC1 and further activating Wnt/β-catenin signaling pathway.
Ginsenoside compound K ameliorates Alzheimer's disease in HT22 cells by adjusting energy metabolism.
Dioscin attenuates Bleomycin-Induced acute lung injury via inhibiting the inflammatory response in mice.
Propentofylline reduces mechanical allodynia and induces mitogen-activated protein kinase phosphatase-1: An experimental study in a rat model of acute incisional pain.
PM(2.5) upregulates rat mesenteric arteries 5-HT(2A) receptor via inflammatory-mediated mitogen-activated protein kinases signaling pathway.
MYCT1 represses apoptosis of laryngeal cancerous cells through the MAX/miR-181a/NPM1 pathway.
LncRNA ADPGK-AS1 regulated cell proliferation, invasion, migration and apoptosis via targeting miR-542-3p in osteosarcoma.
Berberine attenuates XRCC1-mediated base excision repair and sensitizes breast cancer cells to the chemotherapeutic drugs.
Glycine cleavage system determines the fate of pluripotent stem cells via the regulation of senescence and epigenetic modifications.
Cleavage and polyadenylation specific factor 4 promotes colon cancer progression by transcriptionally activating hTERT.
Apigenin reduces the excessive accumulation of lipids induced by palmitic acid via the AMPK signaling pathway in HepG2 cells.
The development of a cell-based model for the assessment of carcinogenic potential upon long-term PM2.5 exposure.
Inhibition of myeloid differentiation 1 specifically in colon with antisense oligonucleotide exacerbates dextran sodium sulfate-induced colitis.
RNA sequencing analysis of the CAL-27 cell response to over-expressed ZNF750 gene revealed an extensive regulation on cell cycle.
Limonin enhances the radiosensitivity of nasopharyngeal carcinoma cells via attenuating Stat3-induced cell stemness.
SIRT1 activation attenuates cardiac fibrosis by endothelial-to-mesenchymal transition.
Inhibition of high mobility group box 1 (HMGB1) attenuates podocyte apoptosis and epithelial-mesenchymal transition by regulating autophagy flux.
MiR-16a Regulates Milk Fat Metabolism by Targeting Large Tumor Suppressor Kinase 1 (LATS1) in Bovine Mammary Epithelial Cells.
Viral N(6)-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus.
CircWHSC1 promotes ovarian cancer progression by regulating MUC1 and hTERT through sponging miR-145 and miR-1182.
Oxidative stress-induced cellular senescence desensitizes cell growth and migration of vascular smooth muscle cells through down-regulation of platelet-derived growth factor receptor-beta.
Tumor vasculature remolding by thalidomide increases delivery and efficacy of cisplatin.
Knockout of neutrophil elastase protects against western diet induced nonalcoholic steatohepatitis in mice by regulating hepatic ceramides metabolism.
SPOP suppresses pancreatic cancer progression by promoting the degradation of NANOG.
Circ-Spidr enhances axon regeneration after peripheral nerve injury.
γ-Oryzanol alleviates acetaminophen-induced liver injury: roles of modulating AMPK/GSK3β/Nrf2 and NF-κB signaling pathways.
Six1 is negatively correlated with poor prognosis and reduces 5-fluorouracil sensitivity via attenuating the stemness of hepatocellular carcinoma cells.
Angiotensin II deteriorates advanced atherosclerosis by promoting MerTK cleavage and impairing efferocytosis through the AT(1)R/ROS/p38 MAPK/ADAM17 pathway.
Melatonin Receptor Mel1b- and Mel1c-mediated Green Light Induced the Secretion of Growth Hormone in Anterior Pituitary of Chicks.
A novel RING finger protein CqRNF152-like with self-ubiquitination activity inhibits white spot syndrome virus infection in a crustacean Cherax quadricarinatus.
Zinc alleviates arsenism in common carp: Varied change profiles of cytokines and tight junction proteins among two intestinal segments.
Molecular cloning, expression and functional analysis of Atg16L1 from orange-spotted grouper (Epinephelus coioides).
Screening candidate microR-15a- IRAK2 regulatory pairs for predicting the response to Staphylococcus aureus-induced mastitis in dairy cows.
Tumor-suppressive activity of Hnf1β in Wilms' tumor.
The protective effects of L-carnitine on myocardial ischaemia-reperfusion injury in patients with rheumatic valvular heart disease undergoing CPB surgery are associated with the suppression of NF-κB pathway and the activation of Nrf2 pathway.
ADP-ribosyltransferase PARP11 modulates the interferon antiviral response by mono-ADP-ribosylating the ubiquitin E3 ligase β-TrCP.
Nonviral Delivery of GRIM-19 Gene Inhibits Tumor Growth with Reduced Local and Systemic Complications.
Long-term exposure of 4-hydroxyestradiol induces the cancer cell characteristics via upregulating CYP1B1 in MCF-10A cells.
Isoflurane produces antidepressant effects inducing BDNF-TrkB signaling in CUMS mice.
Astragaloside IV alleviates myocardial damage induced by type 2 diabetes via improving energy metabolism.
Deep Protein Methylation Profiling by Combined Chemical and Immunoaffinity Approaches Reveals Novel PRMT1 Targets.
Repurposing of the anti-helminthic drug niclosamide to treat melanoma and pulmonary metastasis via the STAT3 signaling pathway.
Increased Tim-3 expression alleviates liver injury by regulating macrophage activation in MCD-induced NASH mice.
LNRRIL6, a novel long noncoding RNA, protects colorectal cancer cells by activating the IL-6-STAT3 pathway.
Inhibition of p53 and/or AKT as a new therapeutic approach specifically targeting ALT cancers.
O-GlcNAcylation of Thr(12)/Ser(56) in short-form O-GlcNAc transferase (sOGT) regulates its substrate selectivity.
LncRNA GABPB1-AS1 and GABPB1 regulate oxidative stress during erastin-induced ferroptosis in HepG2 hepatocellular carcinoma cells.
Porcine Circovirus Type 2 Induces Single Immunoglobulin Interleukin-1 Related Receptor (SIGIRR) Downregulation to Promote Interleukin-1β Upregulation in Porcine Alveolar Macrophage.
Dietary Stevioside Supplementation Alleviates Lipopolysaccharide-Induced Intestinal Mucosal Damage through Anti-Inflammatory and Antioxidant Effects in Broiler Chickens.
Mulberry leaf reduces inflammation and insulin resistance in type 2 diabetic mice by TLRs and insulin Signalling pathway.
Inhibition of PTP1B blocks pancreatic cancer progression by targeting the PKM2/AMPK/mTOC1 pathway.
Self-Assembled saRNA Delivery System Based on Rolling Circle Transcription for Aptamer-Targeting Cancer Therapy.
Tissue plasminogen activator disrupts the blood-brain barrier through increasing the inflammatory response mediated by pericytes after cerebral ischemia.
Chitosan Oligosaccharide Attenuates Nonalcoholic Fatty Liver Disease Induced by High Fat Diet through Reducing Lipid Accumulation, Inflammation and Oxidative Stress in C57BL/6 Mice.
Cardioprotective effects of galectin-3 inhibition against ischemia/reperfusion injury.
Anti-osteoporosis effects of osteoking via reducing reactive oxygen species.
Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications.
Epithelial and interstitial Notch1 activity contributes to the myofibroblastic phenotype and fibrosis.
Dengue Virus M Protein Promotes NLRP3 Inflammasome Activation To Induce Vascular Leakage in Mice.
Epigenetic Memory Is Involved in the Persistent Alterations of Drug-Processing Genes in Adult Mice Due to PCN-Activated PXR During Early Life.
Recombinant porcine NK-lysin inhibits the invasion of hepatocellular carcinoma cells in vitro.
Hepatocyte nuclear factor 1 alpha (HNF1A) regulates transcription of O-GlcNAc transferase in a negative feedback mechanism.
Degradation of Caytaxin Causes Learning and Memory Deficits via Activation of DAPK1 in Aging.
ZW290 Increases Cold Tolerance by Inducing Thermogenesis via the Upregulation of Uncoupling Protein 1 in Brown Adipose Tissue In Vitro and In Vivo.
Inhibition of PI3K/mTOR increased the sensitivity of hepatocellular carcinoma cells to cisplatin via interference with mitochondrial-lysosomal crosstalk.
Homeodomain-interacting protein kinase 2 suppresses proliferation and aerobic glycolysis via ERK/cMyc axis in pancreatic cancer.
Moderate- and Low-Dose of Atorvastatin Alleviate Cognition Impairment Induced by High-Fat Diet via Sirt1 Activation.
Apoptosis and cell cycle arrest of hepatocellular carcinoma spheroids treated by an alternating electric field.
[6]-Gingerol enhances the cisplatin sensitivity of gastric cancer cells through inhibition of proliferation and invasion via PI3K/AKT signaling pathway.
5-aminolevulinic acid photodynamic therapy reduces HPV viral load via autophagy and apoptosis by modulating Ras/Raf/MEK/ERK and PI3K/AKT pathways in HeLa cells.
A novel function of anaphase promoting complex subunit 10 in tumor progression in non-small cell lung cancer.
Nano hydroxyapatite induces glioma cell apoptosis by suppressing NF-κB signaling pathway.
Porcine circovirus type 2 ORF5 protein induces endoplasmic reticulum stress and unfolded protein response in porcine alveolar macrophages.
TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response.
Heat shock factor 1 in cancer-associated fibroblasts is a potential prognostic factor and drives progression of oral squamous cell carcinoma.
LncRNA TPT1-AS1 promotes tumorigenesis and metastasis in epithelial ovarian cancer by inducing TPT1 expression.
Highly Selective Protein Tyrosine Phosphatase Inhibitor, 2,2',3,3'-Tetrabromo-4,4',5,5'-tetrahydroxydiphenylmethane, Ameliorates Type 2 Diabetes Mellitus in BKS db Mice.
Adipose HuR protects against diet-induced obesity and insulin resistance.
Canagliflozin inhibits growth of hepatocellular carcinoma via blocking glucose-influx-induced β-catenin activation.
Fucoidan A2 from the Brown Seaweed Ascophyllum nodosum Lowers Lipid by Improving Reverse Cholesterol Transport in C57BL/6J Mice Fed a High-Fat Diet.
Estrogen negatively regulates the renal epithelial sodium channel (ENaC) by promoting Derlin-1 expression and AMPK activation.
Phosphatase of regenerating liver sensitizes MET to functional activation by hepatocyte growth factor.
Triptolide prevents proliferation and migration of Esophageal Squamous Cell Cancer via MAPK/ERK signaling pathway.
Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs.
MiR-34s negatively regulate homologous recombination through targeting RAD51.
Gambogic acid attenuates liver fibrosis by inhibiting the PI3K/AKT and MAPK signaling pathways via inhibiting HSP90.
Meningitic Escherichia coli-induced upregulation of PDGF-B and ICAM-1 aggravates blood-brain barrier disruption and neuroinflammatory response.
Sodium ferulate protects against influenza virus infection by activation of the TLR7/9-MyD88-IRF7 signaling pathway and inhibition of the NF-κB signaling pathway.
A maternal high-fat, high-sucrose diet induces transgenerational cardiac mitochondrial dysfunction independently of maternal mitochondrial inheritance.
Histone deacetylase 7 inhibits plakoglobin expression to promote lung cancer cell growth and metastasis.
Overexpression of ERBB4 rejuvenates aged mesenchymal stem cells and enhances angiogenesis via PI3K/AKT and MAPK/ERK pathways.
In utero exposure to PM2.5 during gestation caused adult cardiac hypertrophy through histone acetylation modification.
Nuciferine inhibits the progression of glioblastoma by suppressing the SOX2-AKT/STAT3-Slug signaling pathway.
Cysteine Dioxygenase Regulates the Epithelial Morphogenesis of Mammary Gland via Cysteine Sulfinic Acid.
The nanoparticle-facilitated autophagy inhibition of cancer stem cells for improved chemotherapeutic effects on glioblastomas.
Curcumin and Resveratrol Regulate Intestinal Bacteria and Alleviate Intestinal Inflammation in Weaned Piglets.
Effect of Stereochemical Configuration on the Transport and Metabolism of Catechins from Green Tea across Caco-2 Monolayers.
RNA-Binding Motif Protein 24 (RBM24) Is Involved in Pregenomic RNA Packaging by Mediating Interaction between Hepatitis B Virus Polymerase and the Epsilon Element.
GRASP depletion-mediated Golgi destruction decreases cell adhesion and migration via the reduction of α5β1 integrin.
The role of adenosine in up-regulation of p38 MAPK and ERK during limb ischemic preconditioning-induced brain ischemic tolerance.
Purification of cross-linked RNA-protein complexes by phenol-toluol extraction.
CD30 ligand deficiency accelerates glioma progression by promoting the formation of tumor immune microenvironment.
Deficiency of ZnT8 Promotes Adiposity and Metabolic Dysfunction by Increasing Peripheral Serotonin Production.
MicroRNA-145 regulates immune cytokines via targeting FSCN1 in Staphylococcus aureus-induced mastitis in dairy cows.
ERβ modulates genistein's cisplatin-enhancing activities in breast cancer MDA-MB-231 cells via P53-independent pathway.
B-lymphocyte-intrinsic and -extrinsic defects in secretory immunoglobulin A production in the neural crest-conditional deletion of endothelin receptor B model of Hirschsprung-associated enterocolitis.
p62 aggregates mediated Caspase 8 activation is responsible for progression of ovarian cancer.
Age-dependent expression of the vitamin D receptor and the protective effect of vitamin D receptor activation on H(2)O(2)-induced apoptosis in rat intervertebral disc cells.
TUSC3 as a potential biomarker for prognosis in clear cell renal cell carcinoma.
An NLRP3 inflammasome-triggered cytokine storm contributes to Streptococcal toxic shock-like syndrome (STSLS).
Decreased S1P and SPHK2 are involved in pancreatic acinar cell injury.
A promising therapeutic option for diabetic bladder dysfunction: Adipose tissue-derived stem cells pretreated by defocused low-energy shock wave.
High-level expression of PRSS3 correlates with metastasis and poor prognosis in patients with gastric cancer.
Recombinant human arginase I elicited immunosuppression in activated macrophages through inhibiting autophagy.
Rh type C-glycoprotein functions as a novel tumor suppressor gene by inhibiting tumorigenicity and metastasis in head and neck squamous cell carcinoma.
Mechanism of Snhg8/miR-384/Hoxa13/FAM3A axis regulating neuronal apoptosis in ischemic mice model.
ROS/JNK/c-Jun axis is involved in oridonin-induced caspase-dependent apoptosis in human colorectal cancer cells.
TGF-β mediates thoracic radiation-induced abscopal effects of testis injury in rat.
Chitosan Hydrogel Delivery System Containing Herbal Compound Functions as a Potential Antineuroinflammatory Agent.
UHRF1 promotes aerobic glycolysis and proliferation via suppression of SIRT4 in pancreatic cancer.
TRIP4 promotes tumor growth and metastasis and regulates radiosensitivity of cervical cancer by activating MAPK, PI3K/AKT, and hTERT signaling.
Silencing of Aberrant Secretory Protein Expression by Disease-Associated Mutations.
Organophosphorus Flame Retardants Impair Intracellular Lipid Metabolic Function in Human Hepatocellular Cells.
Blocking podoplanin suppresses growth and pulmonary metastasis of human malignant melanoma.
Insulin transcriptionally down-regulates carboxylesterases through pregnane X receptor in an Akt-dependent manner.
Inhibition of Glioma Development by ASCL1-Mediated Direct Neuronal Reprogramming.
Porcine HMGCR Inhibits Porcine Circovirus Type 2 Infection by Directly Interacting with the Viral Proteins.
Sonodynamic therapy inhibits palmitate-induced beta cell dysfunction via PINK1/Parkin-dependent mitophagy.
Macrophage Migration Inhibitory Factor Promotes Chemotaxis of Astrocytes through Regulation of Cholesterol 25-Hydroxylase Following Rat Spinal Cord Injury.
A new split-luciferase complementation assay identifies pentachlorophenol as an inhibitor of apoptosome formation.
Activation of the immunoproteasome protects SH-SY5Y cells from the toxicity of rotenone.
Atractylodin ameliorates lipopolysaccharide and d-galactosamine-induced acute liver failure via the suppression of inflammation and oxidative stress.
MicroRNA-221 sensitizes chronic myeloid leukemia cells to imatinib by targeting STAT5.
Epithelial ovarian cancer stem‑like cells are resistant to the cellular lysis of cytokine‑induced killer cells via HIF1A‑mediated downregulation of ICAM‑1.
Aspirin targets P4HA2 through inhibiting NF-κB and LMCD1-AS1/let-7g to inhibit tumour growth and collagen deposition in hepatocellular carcinoma.
Tubeimoside-1, a triterpenoid saponin, induces cytoprotective autophagy in human breast cancer cells in vitro via Akt-mediated pathway.
Septin 9 isoforms promote tumorigenesis in mammary epithelial cells by increasing migration and ECM degradation through metalloproteinase secretion at focal adhesions.
STAT3 phosphorylation mediates high glucose-impaired cell autophagy in an HDAC1-dependent and -independent manner in Schwann cells of diabetic peripheral neuropathy.
Notch signaling activation induces cell death in MAPKi-resistant melanoma cells.
Complement C3 activation regulates the production of tRNA-derived fragments Gly-tRFs and promotes alcohol-induced liver injury and steatosis.
CtIP promotes G2/M arrest in etoposide-treated HCT116 cells in a p53-independent manner.
DAAM1-mediated migration and invasion of ovarian cancer cells are suppressed by miR-208a-5p.
CDK1 and CDK2 regulate NICD1 turnover and the periodicity of the segmentation clock.
Harnessing the anti-cancer natural product nimbolide for targeted protein degradation.
Observation of novel COX20 mutations related to autosomal recessive axonal neuropathy and static encephalopathy.
Low-dose PCB126 compromises circadian rhythms associated with disordered glucose and lipid metabolism in mice.
UCP2 alleviates tubular epithelial cell apoptosis in lipopolysaccharide-induced acute kidney injury by decreasing ROS production.
Roscovitine attenuates renal interstitial fibrosis in diabetic mice through the TGF-β1/p38 MAPK pathway.
Naringenin ameliorates insulin resistance by modulating endoplasmic reticulum stress in hepatitis C virus-infected liver.
Regulation of CD11b by HIF-1α and the STAT3 signaling pathway contributes to the immunosuppressive function of B cells in inflammatory bowel disease.
Lysine glutarylation in human sperm is associated with progressive motility.
Inhibition of nucleotide synthesis promotes replicative senescence of human mammary epithelial cells.
A novel hydrogen sulfide-releasing donor, HA-ADT, suppresses the growth of human breast cancer cells through inhibiting the PI3K/AKT/mTOR and Ras/Raf/MEK/ERK signaling pathways.
Lingguizhugan decoction attenuates diet-induced obesity and hepatosteatosis via gut microbiota.
Hypoxia inducible factor 1α in vascular smooth muscle cells promotes angiotensin II-induced vascular remodeling via activation of CCL7-mediated macrophage recruitment.
AcMNPV PKIP is associated with nucleocapsid of budded virions and involved in nucleocapsid assembly.
CUL7 E3 Ubiquitin Ligase Mediates the Degradation of Activation-Induced Cytidine Deaminase and Regulates the Ig Class Switch Recombination in B Lymphocytes.
Tri-ortho-cresyl phosphate (TOCP) induced ovarian failure in mice is related to the Hippo signaling pathway disruption.
Autocrine secretions enhance radioresistance in an exosome‑independent manner in NSCLC cells.
miR-132-3p boosts caveolae-mediated transcellular transport in glioma endothelial cells by targeting PTEN/PI3K/PKB/Src/Cav-1 signaling pathway.
Plant-derived alkaloid sinomenine potentiates glucocorticoid pharmacodynamics in mitogen-activated human peripheral blood mononuclear cells by regulating the translocation of glucocorticoid receptor.
MMP-9 Upregulation is Attenuated by the Monoclonal TLR2 Antagonist T2.5 After Oxygen-Glucose Deprivation and Reoxygenation in Rat Brain Microvascular Endothelial Cells.
Function of BRD4 in the pathogenesis of high glucose‑induced cardiac hypertrophy.
SVIP alleviates CCl(4)-induced liver fibrosis via activating autophagy and protecting hepatocytes.
LncRNA SNHG12 inhibits miR-199a to upregulate SIRT1 to attenuate cerebral ischemia/reperfusion injury through activating AMPK signaling pathway.
Reciprocal regulation of integrin β4 and KLF4 promotes gliomagenesis through maintaining cancer stem cell traits.
MMP13 inhibition rescues cognitive decline in Alzheimer transgenic mice via BACE1 regulation.
Mechanism underlying the retarded nuclear translocation of androgen receptor splice variants.
Sodium rutin ameliorates Alzheimer's disease-like pathology by enhancing microglial amyloid-β clearance.
Nucleoporin 107 facilitates the nuclear export of Scn5a mRNA to regulate cardiac bioelectricity.
Effects of Fluoride on Autophagy in Mouse Sertoli Cells.
CDK11(p110) plays a critical role in the tumorigenicity of esophageal squamous cell carcinoma cells and is a potential drug target.
Berberrubine and its analog, hydroxypropyl-berberrubine, regulate LDLR and PCSK9 expression via the ERK signal pathway to exert cholesterol-lowering effects in human hepatoma HepG2 cells.
Intestinal non-canonical NFκB signaling shapes the local and systemic immune response.
Dietary canolol induces apoptosis in human cervical carcinoma HeLa cells through ROS-MAPK mediated mitochondrial signaling pathway: In vitro and in vivo.
Regulation of macrophage iron homeostasis is associated with the localization of bacteria.
Kibra Modulates Learning and Memory via Binding to Dendrin.
miR-33 and RIP140 participate in LPS-induced acute lung injury.
Gene expression profile-based drug screen identifies SAHA as a novel treatment for NAFLD.
The Autographa californica Multiple Nucleopolyhedrovirus ac51 Gene Is Required for Efficient Nuclear Egress of Nucleocapsids and Is Essential for In Vivo Virulence.
SRT1720 retards renal fibrosis via inhibition of HIF1α /GLUT1 in diabetic nephropathy.
JAK2/STAT1-mediated HMGB1 translocation increases inflammation and cell death in a ventilator-induced lung injury model.
LncRNA SNHG4 promotes the proliferation, migration, invasiveness, and epithelial-mesenchymal transition of lung cancer cells by regulating miR-98-5p.
NO donor inhibits proliferation and induces apoptosis by targeting PI3K/AKT/mTOR and MEK/ERK pathways in hepatocellular carcinoma cells.
Carpesium abrotanoides (L.) Root as a Potential Source of Natural Anticancer Compounds: Targeting Glucose Metabolism and PKM2/HIF-1α Axis of Breast Cancer Cells.
Indoxyl sulfate-induced calcification of vascular smooth muscle cells via the PI3K/Akt/NF-κB signaling pathway.
Peroxisome Proliferator-Activated Receptors (PPARs) levels in spermatozoa of normozoospermic and asthenozoospermic men.
LncRNA-241 inhibits 1,2-Dichloroethane-induced hepatic apoptosis.
Lipopolysaccharide-induced DNA damage response activates nuclear factor κB signalling pathway via GATA4 in dental pulp cells.
Transcriptome sequencing of Eospalax fontanierii to determine hypoxia regulation of cardiac fibrinogen.
Dysregulated Transcription Factor TFAP2A After Peripheral Nerve Injury Modulated Schwann Cell Phenotype.
ORP4L couples IP(3) to ITPR1 in control of endoplasmic reticulum calcium release.
Base pair editing in goat: nonsense codon introgression into FGF5 results in longer hair.
Rotenone protects against β-cell apoptosis and attenuates type 1 diabetes mellitus.
S100A9 regulates porcine reproductive and respiratory syndrome virus replication by interacting with the viral nucleocapsid protein.
Tandem repeat sequence of duck circovirus serves as downstream sequence element to regulate viral gene expression.
MicroRNA-181b-5p modulates tumor necrosis factor-α-induced inflammatory responses by targeting interleukin-6 in cementoblasts.
Role of nuclear factor-κB pathway in the transition of mouse secondary follicles to antral follicles.
miR-451a inhibits cancer growth, epithelial-mesenchymal transition and induces apoptosis in papillary thyroid cancer by targeting PSMB8.
Punicalagin Reversed the Hepatic Injury of Tetrachloromethane by Antioxidation and Enhancement of Autophagy.
Hypoxia enhances IL-10-producing B cell generation through upregulating high-mobility group B1 on tumor cell-released autophagosomes.
Novel sphingomyelin biomarkers for brain glioma and associated regulation research on the PI3K/Akt signaling pathway.
Catalpol alleviates adriamycin-induced nephropathy by activating the SIRT1 signalling pathway in vivo and in vitro.
HDAC11 restricts HBV replication through epigenetic repression of cccDNA transcription.
BECN1 promotes the migration of NSCLC cells through regulating the ubiquitination of Vimentin.
Xiaoerfupi alleviates the symptoms of functional dyspepsia by regulating the HTR3A and c-FOS.
Pleiotropic Effects of Epithelial Mesenchymal Crosstalk on Head and Neck Cancer: EMT and beyond.
Endocytic degradation of ErbB2 mediates the effectiveness of neratinib in the suppression of ErbB2-positive ovarian cancer.
Curcumin inhibits LPS-induced neuroinflammation by promoting microglial M2 polarization via TREM2/ TLR4/ NF-κB pathways in BV2 cells.
Critical roles of NLRP3 inflammasome in IL-1β secretion induced by Corynebacterium pseudotuberculosis in vitro.
Activating macrophages for enhanced osteogenic and bactericidal performance by Cu ion release from micro/nano-topographical coating on a titanium substrate.
Oral Administration of Succinoglycan Riclin Improves Diet-Induced Hypercholesterolemia in Mice.
Yes-associated protein regulates podocyte cell cycle re-entry and dedifferentiation in adriamycin-induced nephropathy.
Sal B Alleviates Myocardial Ischemic Injury by Inhibiting TLR4 and the Priming Phase of NLRP3 Inflammasome.
Hydrogen sulfide attenuates mitochondrial dysfunction-induced cellular senescence and apoptosis in alveolar epithelial cells by upregulating sirtuin 1.
Beneficial Effects of Ticagrelor on Oxidized Low-Density Lipoprotein (ox-LDL)-Induced Apoptosis in Human Umbilical Vein Endothelial Cells.
RASAL1 induces to downregulate the SCD1, leading to suppression of cell proliferation in colon cancer via LXRα/SREBP1c pathway.
Stasimon Contributes to the Loss of Sensory Synapses and Motor Neuron Death in a Mouse Model of Spinal Muscular Atrophy.
Gdf11 gene transfer prevents high fat diet-induced obesity and improves metabolic homeostasis in obese and STZ-induced diabetic mice.
Integration of transcriptomics and network analysis deciphers the mechanisms of baicalein in improving learning and memory impairment in senescence-accelerated mouse prone 8 (SAMP8).
Rafoxanide promotes apoptosis and autophagy of gastric cancer cells by suppressing PI3K /Akt/mTOR pathway.
PI3K/Akt inhibitor partly decreases TNF-α-induced activation of fibroblast-like synoviocytes in osteoarthritis.
Aptamer-Based Erythrocyte-Derived Mimic Vesicles Loaded with siRNA and Doxorubicin for the Targeted Treatment of Multidrug-Resistant Tumors.
7-O-geranylquercetin contributes to reverse P-gp-mediated adriamycin resistance in breast cancer.
Fe(3)O(4)@OA@Poloxamer nanoparticles lower triglyceride in hepatocytes through liposuction effect and nano-enzyme effect.
Abnormal expression of Pappa2 gene may indirectly affect mouse hip development through the IGF signaling pathway.
MIF/CD74 axis participates in inflammatory activation of Schwann cells following sciatic nerve injury.
In Vitro Infectious Risk Assessment of Heliothis virescens ascovirus 3j (HvAV-3j) toward Non-target Vertebrate Cells.
PLZF regulates apoptosis of leukemia cells by regulating AKT/Foxo3a pathway.
The effects of fluorene-9-bisphenol on female zebrafish (Danio rerio) reproductive and exploratory behaviors.
17β‑Estradiol protects against interleukin‑1β‑induced apoptosis in rat nucleus pulposus cells via the mTOR/caspase‑3 pathway.
Proteomic Analysis Reveals that Odoroside A Triggers G2/M Arrest and Apoptosis in Colorectal Carcinoma Through ROS-p53 Pathway.
Diosgenin regulates cholesterol metabolism in hypercholesterolemic rats by inhibiting NPC1L1 and enhancing ABCG5 and ABCG8.
HSF1 phosphorylation by cyclosporin A confers hyperthermia sensitivity through suppression of HSP expression.
Sesterterpene MHO7 suppresses breast cancer cells as a novel estrogen receptor degrader.
Proteomic analysis of murine bone marrow derived dendritic cells in response to peste des petits ruminants virus.
Involvement of microRNA-23b-5p in the promotion of cardiac hypertrophy and dysfunction via the HMGB2 signaling pathway.
Interleukin-1 receptor associated kinase (IRAK)-M -mediated type 2 microglia polarization ameliorates the severity of experimental autoimmune encephalomyelitis (EAE).
USP49 potently stabilizes APOBEC3G protein by removing ubiquitin and inhibits HIV-1 replication.
Bone marrow-derived mesenchymal stromal cells promote resistance to tyrosine kinase inhibitors in chronic myeloid leukemia via the IL-7/JAK1/STAT5 pathway.
ANLN-induced EZH2 upregulation promotes pancreatic cancer progression by mediating miR-218-5p/LASP1 signaling axis.
Jingfukang induces anti-cancer activity through oxidative stress-mediated DNA damage in circulating human lung cancer cells.
Platelet-Membrane-Camouflaged Black Phosphorus Quantum Dots Enhance Anticancer Effect Mediated by Apoptosis and Autophagy.
Large-conductance calcium-activated potassium channels mediate lipopolysaccharide-induced activation of murine microglia.
ORMDL3 knockdown in the lungs alleviates airway inflammation and airway remodeling in asthmatic mice via JNK1/2-MMP-9 pathway.
Glial response in early stages of traumatic brain injury.
Divergent engagements between adeno-associated viruses with their cellular receptor AAVR.
BMAL1 Disrupted Intrinsic Diurnal Oscillation in Rat Cerebrovascular Contractility of Simulated Microgravity Rats by Altering Circadian Regulation of miR-103/Ca(V)1.2 Signal Pathway.
Induction of Fibroblast Senescence During Mouse Corneal Wound Healing.
Temporal induction of intestinal epithelial hypoxia-inducible factor-2α is sufficient to drive colitis.
The fucoidan A3 from the seaweed Ascophyllum nodosum enhances RCT-related genes expression in hyperlipidemic C57BL/6J mice.
The fucoidan from the brown seaweed Ascophyllum nodosum ameliorates atherosclerosis in apolipoprotein E-deficient mice.
The status of ω-3 PUFAs influence chronic unpredicted mild stress-induced metabolic side effects in rats through INSIG/SREBP pathway.
LncRNA THOR increases osteosarcoma cell stemness and migration by enhancing SOX9 mRNA stability.
Nerve growth factor prevents arsenic-induced toxicity in PC12 cells through the AKT/GSK-3β/NFAT pathway.
NLRP3 inflammasome plays an important role in caspase-1 activation and IL-1β secretion in macrophages infected with Pasteurella multocida.
Curcumin exerts cytotoxicity dependent on reactive oxygen species accumulation in non-small-cell lung cancer cells.
Downregulation of RGMA by HIF-1A/miR-210-3p axis promotes cell proliferation in oral squamous cell carcinoma.
Aspirin ameliorates lung cancer by targeting the miR-98/WNT1 axis.
Human cells are permissive for the productive infection of porcine circovirus type 2 in vitro.
LncRNA SNHG20 predicts a poor prognosis and promotes cell progression in epithelial ovarian cancer.
UBE2C functions as a potential oncogene by enhancing cell proliferation, migration, invasion, and drug resistance in hepatocellular carcinoma cells.
Zearalenone Induces Estrogen-Receptor-Independent Neutrophil Extracellular Trap Release in Vitro.
Excessive miR-25-3p maturation via N(6)-methyladenosine stimulated by cigarette smoke promotes pancreatic cancer progression.
Icariin attenuates neuroinflammation and exerts dopamine neuroprotection via an Nrf2-dependent manner.
Ntrk1 Promotes Resistance to PD-1 Checkpoint Blockade in Mesenchymal Kras/p53 Mutant Lung Cancer.
Macrophage migration inhibitory factor facilitates prostaglandin E(2) production of astrocytes to tune inflammatory milieu following spinal cord injury.
MicroRNA-106b Regulates Milk Fat Metabolism via ATP Binding Cassette Subfamily A Member 1 ( ABCA1) in Bovine Mammary Epithelial Cells.
Immunomodulatory effects of an acidic polysaccharide fraction from herbal Gynostemma pentaphyllum tea in RAW264.7 cells.
Exosomal ephrinA2 derived from serum as a potential biomarker for prostate cancer.
AMPH-1 is critical for breast cancer progression.
The Protective Effect of Astaxanthin on Cognitive Function via Inhibition of Oxidative Stress and Inflammation in the Brains of Chronic T2DM Rats.
Maternal Protein Restriction Induces Alterations in Hepatic Unfolded Protein Response-Related Molecules in Adult Rat Offspring.
β-TrCP Restricts Lipopolysaccharide (LPS)-Induced Activation of TRAF6-IKK Pathway Upstream of IκBα Signaling.
The Host Restriction Factor Interferon-Inducible Transmembrane Protein 3 Inhibits Vaccinia Virus Infection.
Protective Effect of Extract of Bletilla Striata on Isoflurane Induced Neuronal Injury By Altering PI3K/Akt Pathway.
Magnolol Alleviates Inflammatory Responses and Lipid Accumulation by AMP-Activated Protein Kinase-Dependent Peroxisome Proliferator-Activated Receptor α Activation.
Geniposide and Chlorogenic Acid Combination Ameliorates Non-alcoholic Steatohepatitis Involving the Protection on the Gut Barrier Function in Mouse Induced by High-Fat Diet.
Oncolytic Newcastle disease virus induces autophagy-dependent immunogenic cell death in lung cancer cells.
Add-On therapy with Chinese herb medicine Bo-Er-Ning capsule (BENC) improves outcomes of gastric cancer patients: a randomized clinical trial followed with bioinformatics-assisted mechanism study.
Liposomal Curcumin Targeting Endometrial Cancer Through the NF-κB Pathway.
Placental growth factor promotes epithelial-mesenchymal transition-like changes in ARPE-19 cells under hypoxia.
Dorsal Root Ganglion Maintains Stemness of Bone Marrow Mesenchymal Stem Cells by Enhancing Autophagy through the AMPK/mTOR Pathway in a Coculture System.
Glucagon-Like Peptide-1 Mediates the Protective Effect of the Dipeptidyl Peptidase IV Inhibitor on Renal Fibrosis via Reducing the Phenotypic Conversion of Renal Microvascular Cells in Monocrotaline-Treated Rats.
Oxidative stress and NF-κB signaling are involved in LPS induced pulmonary dysplasia in chick embryos.
Foot-and-mouth disease virus capsid protein VP2 activates the cellular EIF2S1-ATF4 pathway and induces autophagy via HSPB1.
TRIM59 regulates autophagy through modulating both the transcription and the ubiquitination of BECN1.
Linagliptin unmasks specific antioxidant pathways protective against albuminuria and kidney hypertrophy in a mouse model of diabetes.
Dysregulation of Neuregulin-1/ErbB signaling in the hippocampus of rats after administration of doxorubicin.
Involvement of microRNA-146a in diabetic peripheral neuropathy through the regulation of inflammation.
Expression and significance of the Hedgehog signal transduction pathway in oxygen-induced retinal neovascularization in mice.
miR-222-3p promotes osteosarcoma cell migration and invasion through targeting TIMP3.
Protective Effect of Hydrogen on Sodium Iodate-Induced Age-Related Macular Degeneration in Mice.
Dl-3-n-Butylphthalide improves lipopolysaccharide-induced depressive-like behavior in rats: involvement of Nrf2 and NF-κB pathways.
miR-34b-5p inhibition attenuates lung inflammation and apoptosis in an LPS-induced acute lung injury mouse model by targeting progranulin.
Amyotrophic lateral sclerosis (ALS) and Alzheimer's disease (AD) are characterised by differential activation of ER stress pathways: focus on UPR target genes.
Exosomal zinc transporter ZIP4 promotes cancer growth and is a novel diagnostic biomarker for pancreatic cancer.
Disruption of Tmem30a results in cerebellar ataxia and degeneration of Purkinje cells.
The regulatory effects of metformin on the [SNAIL/miR-34]:[ZEB/miR-200] system in the epithelial-mesenchymal transition(EMT) for colorectal cancer(CRC).
Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors.
Transcriptomic but not genomic variability confers phenotype of breast cancer stem cells.
Cattle Encephalon Glycoside and Ignotin Reduce Early Brain Injury and Cognitive Dysfunction after Subarachnoid Hemorrhage in Rats.
Cutting Edge: Dysregulated CARD9 Signaling in Neutrophils Drives Inflammation in a Mouse Model of Neutrophilic Dermatoses.
Resveratrol Suppresses Matrix Metalloproteinase-2 Activation Induced by Lipopolysaccharide in Mouse Osteoblasts via Interactions with AMP-Activated Protein Kinase and Suppressor of Cytokine Signaling 1.
The apoptosis in arsenic-induced oxidative stress is associated with autophagy in the testis tissues of chicken.
Dipeptidyl peptidase IV (DPP-4) inhibition alleviates pulmonary arterial remodeling in experimental pulmonary hypertension.
Bone morphogenetic protein 4 expression in the developing lumbosacral spinal cord of rat embryos with anorectal malformations.
MicroRNA-543 functions as an osteogenesis promoter in human periodontal ligament-derived stem cells by inhibiting transducer of ERBB2, 2.
Curcumol induces RIPK1/RIPK3 complex-dependent necroptosis via JNK1/2-ROS signaling in hepatic stellate cells.
Quantitative Global Proteome and Lysine Succinylome Analyses Reveal the Effects of Energy Metabolism in Renal Cell Carcinoma.
Salidroside attenuates endothelial cellular senescence via decreasing the expression of inflammatory cytokines and increasing the expression of SIRT3.
TRIM65 supports bladder urothelial carcinoma cell aggressiveness by promoting ANXA2 ubiquitination and degradation.
Cyclophilin J limits inflammation through the blockage of ubiquitin chain sensing.
Quercetin ameliorates podocyte injury via inhibition of oxidative stress and the TGF-β1/Smad pathway in DN rats.
Apelin-13 Upregulates BDNF Against Chronic Stress-induced Depression-like Phenotypes by Ameliorating HPA Axis and Hippocampal Glucocorticoid Receptor Dysfunctions.
Reduced graphene oxide triggered epithelial-mesenchymal transition in A549 cells.
Andrographolide inhibits breast cancer through suppressing COX-2 expression and angiogenesis via inactivation of p300 signaling and VEGF pathway.
SUMO-1 modification of FEN1 facilitates its interaction with Rad9-Rad1-Hus1 to counteract DNA replication stress.
Fluoride induces apoptosis and autophagy through the IL-17 signaling pathway in mice hepatocytes.
Atorvastatin Pretreatment Attenuates Ischemic Brain Edema by Suppressing Aquaporin 4.
Oncogenic activation of PI3K induces progenitor cell differentiation to suppress epidermal growth.
(2R,3R)Dihydromyricetin inhibits osteoclastogenesis and bone loss through scavenging LPS-induced oxidative stress and NF-κB and MAPKs pathways activating.
NR2B-Tyr phosphorylation regulates synaptic plasticity in central sensitization in a chronic migraine rat model.
MicroRNA-32 Regulates Development and Progression of Hepatocellular Carcinoma by Targeting ADAMTS9 and Affects Its Prognosis.
Zinc finger E-box-binding homeobox 1 mediates aerobic glycolysis via suppression of sirtuin 3 in pancreatic cancer.
Estrogen receptor β upregulated by lncRNA-H19 to promote cancer stem-like properties in papillary thyroid carcinoma.
Citrus Tangeretin Improves Skeletal Muscle Mitochondrial Biogenesis via Activating the AMPK-PGC1-α Pathway In Vitro and In Vivo: A Possible Mechanism for Its Beneficial Effect on Physical Performance.
Nitric oxide triggers the assembly of "type II" stress granules linked to decreased cell viability.
Inhibitor of Bruton's tyrosine kinases, PCI-32765, decreases pro-inflammatory mediators' production in high glucose-induced macrophages.
Overexpression of collagen type V α1 chain in human breast invasive ductal carcinoma is mediated by TGF-β1.
Establishment of a human embryonic stem cell line with homozygous TP53 R248W mutant by TALEN mediated gene editing.
Induction of OTUD1 by RNA viruses potently inhibits innate immune responses by promoting degradation of the MAVS/TRAF3/TRAF6 signalosome.
Systemic administration of scAAV9-IGF1 extends survival in SOD1(G93A) ALS mice via inhibiting p38 MAPK and the JNK-mediated apoptosis pathway.
Exogenous leptin affects sperm parameters and impairs blood testis barrier integrity in adult male mice.
Promotion of autophagosome-lysosome fusion via salvianolic acid A-mediated SIRT1 up-regulation ameliorates alcoholic liver disease.
IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation.
Effect of propolis on preserving human periodontal ligament cells and regulating pro-inflammatory cytokines.
Hepatoprotection of auraptene from peels of citrus fruits against thioacetamide-induced hepatic fibrosis in mice by activating farnesoid X receptor.
TRIM50 suppressed hepatocarcinoma progression through directly targeting SNAIL for ubiquitous degradation.
Geniposide attenuates Aβ(25-35)-induced neurotoxicity via the TLR4/NF-κB pathway in HT22 cells.
Renal protective effect of Paeoniflorin by inhibition of JAK2/STAT3 signaling pathway in diabetic mice.
Cell Cycle Regulation by Alternative Polyadenylation of CCND1.
Dietary α-Mangostin Provides Protective Effects against Acetaminophen-Induced Hepatotoxicity in Mice via Akt/mTOR-Mediated Inhibition of Autophagy and Apoptosis.
ASK1/2 signaling promotes inflammation in a mouse model of neutrophilic dermatosis.
Innately activated TLR4 signal in the nucleus accumbens is sustained by CRF amplification loop and regulates impulsivity.
Effects of gelling bath on the physical properties of alginate gel beads and the biological characteristics of entrapped HepG2 cells.
Insulin Treatment Cannot Promote Lipogenesis in Rat Fetal Lung in Gestational Diabetes Mellitus Because of Failure to Redress the Imbalance Among SREBP-1, SCAP, and INSIG-1.
Ubenimex, an APN inhibitor, could serve as an anti‑tumor drug in RT112 and 5637 cells by operating in an Akt‑associated manner.
LIFR increases the release of soluble endoglin via the upregulation of MMP14 expression in preeclampsia.
7α,8α-Epoxynagilactones and their glucosides from the twigs of Podocarpus nagi: Isolation, structures, and cytotoxic activities.
Elucidation of the Molecular-Mechanisms and In Vivo Evaluation of the Anti-inflammatory Effect of Alginate-Derived Seleno-polymannuronate.
Nicotine-Induced Neuroprotection against Cognitive Dysfunction after Partial Hepatectomy Involves Activation of BDNF/TrkB Signaling Pathway and Inhibition of NF-κB Signaling Pathway in Aged Rats.
Correction and Republication: Effect of Di-(2-ethylhexyl) phthalate on the hypothalamus-pituitary-thyroid axis in adolescent rat.
Exosomes from C2C12 myoblasts enhance osteogenic differentiation of MC3T3-E1 pre-osteoblasts by delivering miR-27a-3p.
New Drug Candidate Targeting the 4A1 Orphan Nuclear Receptor for Medullary Thyroid Cancer Therapy.
Apoptosome formation upon overexpression of native and truncated Apaf-1 in cell-free and cell-based systems.
Mitochondrial Dysfunctions Contribute to Hypertrophic Cardiomyopathy in Patient iPSC-Derived Cardiomyocytes with MT-RNR2 Mutation.
Cell division cycle 7 is a potential therapeutic target in oral squamous cell carcinoma and is regulated by E2F1.
IL-6 receptor blockade ameliorates diabetic nephropathy via inhibiting inflammasome in mice.
Metformin inhibits ovarian cancer via decreasing H3K27 trimethylation.
Avian leukosis virus subgroup J promotes cell proliferation and cell cycle progression through miR-221 by targeting CDKN1B.
PEDF improves cardiac function in rats subjected to myocardial ischemia/reperfusion injury by inhibiting ROS generation via PEDF‑R.
Effect of Banxia Xiexin decoction on Helicobacter pylori-related peptic ulcers and its possible mechanism via the TGF-β/Smad signaling pathway.
Doxycycline attenuates chronic intermittent hypoxia-induced atrial fibrosis in rats.
Cysteine-rich protein 61 regulates adipocyte differentiation from mesenchymal stem cells through mammalian target of rapamycin complex 1 and canonical Wnt signaling.
A comparison of CRISPR/Cas9 and siRNA-mediated ALDH2 gene silencing in human cell lines.
Effects of nicotine on the metabolism and gene expression profile of Sprague‑Dawley rat primary osteoblasts.
Myxovirus resistance protein A inhibits hepatitis C virus replication through JAK-STAT pathway activation.
Berberine exerts antioxidant effects via protection of spiral ganglion cells against cytomegalovirus-induced apoptosis.
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Enhancer of zeste homolog 2 promotes cisplatin resistance by reducing cellular platinum accumulation.
Acetylation of oxidized base repair-initiating NEIL1 DNA glycosylase required for chromatin-bound repair complex formation in the human genome increases cellular resistance to oxidative stress.
Mussel adhesive protein fused with VE-cadherin domain specifically triggers endothelial cell adhesion.
Procyanidin B2 mitigates behavioral impairment and protects myelin integrity in cuprizone-induced schizophrenia in mice.
Effects of Levonorgestrel and progesterone on Oviductal physiology in mammals.
Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.
DRm217 attenuates myocardial ischemia-reperfusion injury via stabilizing plasma membrane Na(+)-K(+)-ATPase, inhibiting Na(+)-K(+)-ATPase/ROS pathway and activating PI3K/Akt and ERK1/2.
Long noncoding RNA lncARSR promotes hepatic cholesterol biosynthesis via modulating Akt/SREBP-2/HMGCR pathway.
Underexpression of Receptor for Activated C Kinase 1 (RACK1) in Leukocytes from Patients with Severe Acute Pancreatitis.
Generation and propagation of yeast prion [URE3] are elevated under electromagnetic field.
Japanese encephalitis virus induces apoptosis by inhibiting Foxo signaling pathway.
Membrane topology of rat sodium-coupled neutral amino acid transporter 2 (SNAT2).
Rapamycin and ZSTK474 can have differential effects at different post‑infection time‑points regarding CVB3 replication and CVB3‑induced autophagy.
Chronic stress causes protein kinase C epsilon-aldehyde dehydrogenase 2 signaling pathway perturbation in the rat hippocampus and prefrontal cortex, but not in the myocardium.
A Polysaccharide Isolated from Dictyophora indusiata Promotes Recovery from Antibiotic-Driven Intestinal Dysbiosis and Improves Gut Epithelial Barrier Function in a Mouse Model.
The actin cytoskeletal architecture of estrogen receptor positive breast cancer cells suppresses invasion.
Myc activity is required for maintenance of the neuromesodermal progenitor signalling network and for segmentation clock gene oscillations in mouse.
Synthesis and structure-activity relationship studies of MI-2 analogues as MALT1 inhibitors.
Blocking the Thiol at Cysteine-322 Destabilizes Tau Protein and Prevents Its Oligomer Formation.
ATXN3 Positively Regulates Type I IFN Antiviral Response by Deubiquitinating and Stabilizing HDAC3.
Vitamin C increases 5-hydroxymethylcytosine level and inhibits the growth of bladder cancer.
A novel small-molecule activator of Sirtuin-1 induces autophagic cell death/mitophagy as a potential therapeutic strategy in glioblastoma.
A reproducible swine model of proximal descending thoracic aortic aneurysm created with intra-adventitial application of elastase.
Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.
Hypoxia induces the dysfunction of human endothelial colony-forming cells via HIF-1α signaling.
Mechanism of prolactin inhibition of miR-135b via methylation in goat mammary epithelial cells.
Selectivity, cell permeability and oral availability studies of novel bromophenol derivative HPN as protein tyrosine phosphatase 1B inhibitor.
Clinical efficacy of recombinant human latrophilin 3 antibody in the treatment of pediatric asthma.
PTEN-L promotes type I interferon responses and antiviral immunity.
Epithelial-mesenchymal crosstalk induces radioresistance in HNSCC cells.
Wnt/β-catenin pathway promotes acute lung injury induced by LPS through driving the Th17 response in mice.
Comparative Proteomics Analysis Identifies Cdc42-Cdc42BPA Signaling as Prognostic Biomarker and Therapeutic Target for Colon Cancer Invasion.
Rhubarb Supplementation Promotes Intestinal Mucosal Innate Immune Homeostasis through Modulating Intestinal Epithelial Microbiota in Goat Kids.
Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
SOCE induced calcium overload regulates autophagy in acute pancreatitis via calcineurin activation.
Autophagy promotes metastasis and glycolysis by upregulating MCT1 expression and Wnt/β-catenin signaling pathway activation in hepatocellular carcinoma cells.
Increased Expression of Cullin 3 in Nasopharyngeal Carcinoma and Knockdown Inhibits Proliferation and Invasion.
Proteasome Inhibitor Carbobenzoxy-L-Leucyl-L-Leucyl-L-Leucinal (MG132) Enhances Therapeutic Effect of Paclitaxel on Breast Cancer by Inhibiting Nuclear Factor (NF)-κB Signaling.
miR-3189-3p Mimics Enhance the Effects of S100A4 siRNA on the Inhibition of Proliferation and Migration of Gastric Cancer Cells by Targeting CFL2.
Uncovering the anticancer mechanism of Compound Kushen Injection against HCC by integrating quantitative analysis, network analysis and experimental validation.
Dietary Supplement of Large Yellow Tea Ameliorates Metabolic Syndrome and Attenuates Hepatic Steatosis in db/db Mice.
Repulsive guidance molecule a suppresses angiogenesis after ischemia/reperfusion injury of middle cerebral artery occlusion in rats.
Protein Kinase A/CREB Signaling Prevents Adriamycin-Induced Podocyte Apoptosis via Upregulation of Mitochondrial Respiratory Chain Complexes.
Eukaryotic translation initiation factor 2 subunit α (eIF2α) inhibitor salubrinal attenuates paraquat-induced human lung epithelial-like A549 cell apoptosis by regulating the PERK-eIF2α signaling pathway.
RhPDCD5 combined with dexamethasone increases antitumor activity in multiple myeloma partially via inhibiting the Wnt signalling pathway.
Aberrant expression of miR-451a contributes to 1,2-dichloroethane-induced hepatic glycerol gluconeogenesis disorder by inhibiting glycerol kinase expression in NIH Swiss mice.
Ephrin receptor A2 is an epithelial cell receptor for Epstein-Barr virus entry.
Carnosol-mediated Sirtuin 1 activation inhibits Enhancer of Zeste Homolog 2 to attenuate liver fibrosis.
N-oleoylethanolamide suppresses intimal hyperplasia after balloon injury in rats through AMPK/PPARα pathway.
PUM1 promotes ovarian cancer proliferation, migration and invasion.
Interferon-alpha enhances the antitumour activity of EGFR-targeted therapies by upregulating RIG-I in head and neck squamous cell carcinoma.
Involvement of impaired autophagy and mitophagy in Neuro-2a cell damage under hypoxic and/or high-glucose conditions.
Hypoxia Activates Src and Promotes Endocytosis Which Decreases MMP-2 Activity and Aggravates Renal Interstitial Fibrosis.
The RARS-MAD1L1 Fusion Gene Induces Cancer Stem Cell-like Properties and Therapeutic Resistance in Nasopharyngeal Carcinoma.
Ajudecumin A from Ajuga ovalifolia var. calantha exhibits anti-inflammatory activity in lipopolysaccharide-activated RAW264.7 murine macrophages and animal models of acute inflammation.
Effects of garlic polysaccharide on alcoholic liver fibrosis and intestinal microflora in mice.
Involvement of PINK1/Parkin-mediated mitophagy in paraquat- induced apoptosis in human lung epithelial-like A549 cells.
Oxymatrine attenuates brain hypoxic-ischemic injury from apoptosis and oxidative stress: role of p-Akt/GSK3β/HO-1/Nrf-2 signaling pathway.
RNF126 Quenches RNF168 Function in the DNA Damage Response.
1,3-Dichloro-2-Propanol inhibits autophagy via P53/AMPK/mTOR pathway in HepG2 cells.
Urea transport B gene induces melanoma B16 cell death via activation of p53 and mitochondrial apoptosis.
Type 3 innate lymphoid cell: a new player in liver fibrosis progression.
Long non-coding RNA BRE-AS1 represses non-small cell lung cancer cell growth and survival via up-regulating NR4A3.
Distinct autophagy-inducing abilities of similar-sized nanoparticles in cell culture and live C. elegans.
Protein A from orange-spotted grouper nervous necrosis virus triggers type I interferon production in fish cell.
Overcoming resistance to mitochondrial apoptosis by BZML-induced mitotic catastrophe is enhanced by inhibition of autophagy in A549/Taxol cells.
Osteoglycin-induced VEGF Inhibition Enhances T Lymphocytes Infiltrating in Colorectal Cancer.
Restoration of 5-hydroxymethylcytosine by ascorbate blocks kidney tumour growth.
Matrine inhibits the proliferation and migration of lung cancer cells through regulation of the protein kinase B/glycogen synthase kinase-3β signaling pathways.
TNFSF14/LIGHT, a Non-Canonical NF-κB Stimulus, Induces the HIF Pathway.
miR-346 Promotes HCC Progression by Suppressing Breast Cancer Metastasis Suppressor 1 Expression.
NRAGE confers poor prognosis and promotes proliferation, invasion, and chemoresistance in gastric cancer.
Selenium-enriched yeast inhibited β-amyloid production and modulated autophagy in a triple transgenic mouse model of Alzheimer's disease.
Effects of Dahuang zhechong pill on doxorubicin-resistant SMMC-7721 xenografts in mice.
Uncoupling protein 1 expression in adipocytes derived from skeletal muscle fibro/adipogenic progenitors is under genetic and hormonal control.
Role of TGF-β activated kinase-1 inhibitor on the interaction between macrophages and mesangial cells on the condition of high glucose.
MiR-151a is involved in the pathogenesis of atopic dermatitis by regulating interleukin-12 receptor β2.
TIPE2 is negatively correlated with tissue factor and thrombospondin-1 expression in patients with bronchial asthma.
The enhancement of siPLK1 penetration across BBB and its anti glioblastoma activity in vivo by magnet and transferrin co-modified nanoparticle.
Identification of novel Nrf2 activators from Cinnamomum chartophyllum H.W. Li and their potential application of preventing oxidative insults in human lung epithelial cells.
Catalpol ameliorates hepatic insulin resistance in type 2 diabetes through acting on AMPK/NOX4/PI3K/AKT pathway.
Protective effect of methylallyl sulfone in the development of cigarette smoke extract-induced apoptosis in rats and HFL-1 cells.
Smurf1 restricts the antiviral function mediated by USP25 through promoting its ubiquitination and degradation.
GRASP55 Senses Glucose Deprivation through O-GlcNAcylation to Promote Autophagosome-Lysosome Fusion.
Pathological Features of Staphylococcus aureus Induced Mastitis in Dairy Cows and Isobaric-Tags-for-Relative-and-Absolute-Quantitation Proteomic Analyses.
Role of silent information regulator 1 in the protective effect of hydrogen sulfide on homocysteine-induced cognitive dysfunction: Involving reduction of hippocampal ER stress.
Differential CRABP-II and FABP5 expression patterns and implications for medulloblastoma retinoic acid sensitivity.
Nogo-B receptor promotes epithelial-mesenchymal transition in non-small cell lung cancer cells through the Ras/ERK/Snail1 pathway.
GRHL2 suppresses tumor metastasis via regulation of transcriptional activity of RhoG in non-small cell lung cancer.
Silencing Rab14 represses the proliferation and migration of oral squamous cell carcinoma, and enhances cisplatin sensitivity.
3-Mercaptopyruvate Sulfurtransferase, Not Cystathionine β-Synthase Nor Cystathionine γ-Lyase, Mediates Hypoxia-Induced Migration of Vascular Endothelial Cells.
Antimycobacterial and Anti-inflammatory Mechanisms of Baicalin via Induced Autophagy in Macrophages Infected with Mycobacterium tuberculosis.
Variant Amino Acid Residues Alter the Enzyme Activity of Peanut Type 2 Diacylglycerol Acyltransferases.
Iridoids with Genipin Stem Nucleus Inhibit Lipopolysaccharide-Induced Inflammation and Oxidative Stress by Blocking the NF-κB Pathway in Polycystic Ovary Syndrome.
The USP7 Inhibitor P5091 Induces Cell Death in Ovarian Cancers with Different P53 Status.
α-Lipoic Acid Promotes Neurological Recovery After Ischemic Stroke by Activating the Nrf2/HO-1 Pathway to Attenuate Oxidative Damage.
Targeted kinase inhibition relieves slowness and tremor in a Drosophila model of LRRK2 Parkinson's disease.
Endoplasmic Reticulum Stress Is Involved in Cochlear Cell Apoptosis in a Cisplatin-Induced Ototoxicity Rat Model.
Role of Zebrafish fhl1A in Satellite Cell and Skeletal Muscle Development.
XRCC5 cooperates with p300 to promote cyclooxygenase-2 expression and tumor growth in colon cancers.
miR-125b-5p functions as a tumor suppressor gene partially by regulating HMGA2 in esophageal squamous cell carcinoma.
Autophagy promotes degradation of polyethyleneimine-alginate nanoparticles in endothelial progenitor cells.
Curcumin Activates AMPK Pathway and Regulates Lipid Metabolism in Rats Following Prolonged Clozapine Exposure.
Paeoniflorin attenuates incipient diabetic nephropathy in streptozotocin-induced mice by the suppression of the Toll-like receptor-2 signaling pathway.
Roux-en-Y Gastric Bypass Improves Hepatic Glucose Metabolism Involving Down-Regulation of Protein Tyrosine Phosphatase 1B in Obese Rats.
HOXD-AS1 functions as an oncogenic ceRNA to promote NSCLC cell progression by sequestering miR-147a.
Transcription Factor NFAT5 Promotes Glioblastoma Cell-driven Angiogenesis via SBF2-AS1/miR-338-3p-Mediated EGFL7 Expression Change.
Identification of Flavin-Containing Monooxygenase 5 (FMO5) as a Regulator of Glucose Homeostasis and a Potential Sensor of Gut Bacteria.
Visfatin induces the apoptosis of endothelial progenitor cells via the induction of pro-inflammatory mediators through the NF-κB pathway.
Mechanism of Lycium barbarum polysaccharides on primary cultured rat hippocampal neurons.
Downregulation of serum RAB27B confers improved prognosis and is associated with hepatocellular carcinoma progression through PI3K-AKT-P21 signaling.
Vegetally localised Vrtn functions as a novel repressor to modulate bmp2b transcription during dorsoventral patterning in zebrafish.
Dendrobium nobile Lindl. alkaloids regulate metabolism gene expression in livers of mice.
APPL1 promotes the migration of gastric cancer cells by regulating Akt2 phosphorylation.
Thrombospondin-1 Production Regulates the Inflammatory Cytokine Secretion in THP-1 Cells Through NF-κB Signaling Pathway.
An Important Function of Petrosiol E in Inducing the Differentiation of Neuronal Progenitors and in Protecting Them against Oxidative Stress.
Anti-inflammatory capacity of Lactobacillus rhamnosus GG in monophasic variant Salmonella infected piglets is correlated with impeding NLRP6-mediated host inflammatory responses.
Ovarian cancer proliferation and apoptosis are regulated by human transfer RNA methyltransferase 9-likevia LIN9.
High expression of IL-4R enhances proliferation and invasion of hepatocellular carcinoma cells.
The role of long non-coding RNA PCA3 in epithelial ovarian carcinoma tumorigenesis and progression.
Inhibition of Starvation-Triggered Endoplasmic Reticulum Stress, Autophagy, and Apoptosis in ARPE-19 Cells by Taurine through Modulating the Expression of Calpain-1 and Calpain-2.
Evidence for a direct cross-talk between malic enzyme and the pentose phosphate pathway via structural interactions.
Ligand-dependent EphA7 signaling inhibits prostate tumor growth and progression.
Fluoride-Induced Autophagy via the Regulation of Phosphorylation of Mammalian Targets of Rapamycin in Mice Leydig Cells.
MicroRNA-23a promotes pancreatic cancer metastasis by targeting epithelial splicing regulator protein 1.
Epigenetic silencing of ASPP1 confers 5-FU resistance in clear cell renal cell carcinoma by preventing p53 activation.
Cryptotanshinone sensitizes antitumor effect of paclitaxel on tongue squamous cell carcinoma growth by inhibiting the JAK/STAT3 signaling pathway.
Spatiotemporal Expression of Bcl-2/Bax and Neural Cell Apoptosis in the Developing Lumbosacral Spinal Cord of Rat Fetuses with Anorectal Malformations.
Sialic acid-modified solid lipid nanoparticles as vascular endothelium-targeting carriers for ischemia-reperfusion-induced acute renal injury.
Lack of BACE1 S-palmitoylation reduces amyloid burden and mitigates memory deficits in transgenic mouse models of Alzheimer's disease.
Cell-autonomous adiposity through increased cell surface GLUT4 due to ankyrin-B deficiency.
Proteomics and metabolomics analysis of hepatic mitochondrial metabolism in alcohol-preferring and non-preferring rats.
Copper or/and arsenic induce oxidative stress-cascaded, nuclear factor kappa B-dependent inflammation and immune imbalance, trigging heat shock response in the kidney of chicken.
Hydrogen Sulfide Inhibits Chronic Unpredictable Mild Stress-Induced Depressive-Like Behavior by Upregulation of Sirt-1: Involvement in Suppression of Hippocampal Endoplasmic Reticulum Stress.
Inhibition of tissue transglutaminase attenuates lipopolysaccharide-induced inflammation in glial cells through AKT/mTOR signal pathway.
FGF7/FGFR2 signal promotes invasion and migration in human gastric cancer through upregulation of thrombospondin-1.
Embelin attenuates adipogenesis and lipogenesis through activating canonical Wnt signaling and inhibits high-fat diet-induced obesity.
Preliminary evaluation for Bit1 as a potential biomarker for squamous cell carcinoma and adenocarcinoma of esophagus.
Sulforaphane-cysteine induces apoptosis by sustained activation of ERK1/2 and caspase 3 in human glioblastoma U373MG and U87MG cells.
oxLDL antibody inhibits MCP-1 release in monocytes/macrophages by regulating Ca(2+) /K(+) channel flow.
TET3-mediated DNA oxidation promotes ATR-dependent DNA damage response.
Menin enhances c-Myc-mediated transcription to promote cancer progression.
Thyroid stimulating hormone increases hepatic gluconeogenesis via CRTC2.
Longikaurin A, a natural ent-kaurane, suppresses stemness in nasopharyngeal carcinoma cells.
Hypoxia promotes chemotherapy resistance by down-regulating SKA1 gene expression in human osteosarcoma.
miR-148a and miR-17-5p synergistically regulate milk TAG synthesis via PPARGC1A and PPARA in goat mammary epithelial cells.
MicroRNA-17-92 Regulates the Transcription Factor E2F3b during Myogenesis In Vitro and In Vivo.
Probiotics may delay the progression of nonalcoholic fatty liver disease by restoring the gut microbiota structure and improving intestinal endotoxemia.
Anti-tumor effect of evodiamine by inducing Akt-mediated apoptosis in hepatocellular carcinoma.
AMPK/α-Ketoglutarate Axis Regulates Intestinal Water and Ion Homeostasis in Young Pigs.
Upregulation of microRNA-574-3p in a human gastric cancer cell line AGS by TGF-β1.
A coumarin-based fluorescence resonance energy transfer probe targeting matrix metalloproteinase-2 for the detection of cervical cancer.
Sulforaphane prevents bleomycin‑induced pulmonary fibrosis in mice by inhibiting oxidative stress via nuclear factor erythroid 2‑related factor‑2 activation.
Cerebrolysin alleviates cognitive deficits induced by chronic cerebral hypoperfusion by increasing the levels of plasticity-related proteins and decreasing the levels of apoptosis-related proteins in the rat hippocampus.
CADASIL mutant NOTCH3(R90C) decreases the viability of HS683 oligodendrocytes via apoptosis.
The MBNL3 splicing factor promotes hepatocellular carcinoma by increasing PXN expression through the alternative splicing of lncRNA-PXN-AS1.
Malvidin and cyanidin derivatives from açai fruit (Euterpe oleracea Mart.) counteract UV-A-induced oxidative stress in immortalized fibroblasts.
Selenium-Containing Polysaccharide-Protein Complex in Se-Enriched Ulva fasciata Induces Mitochondria-Mediated Apoptosis in A549 Human Lung Cancer Cells.
Deubiquitinase USP33 is negatively regulated by β-TrCP through ubiquitin-dependent proteolysis.
Transcription regulator TRIP-Br2 mediates ER stress-induced brown adipocytes dysfunction.
The role of the ATM/Chk/P53 pathway in mediating DNA damage in hand-foot syndrome induced by PLD.
Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin.
Knockdown of TREM-1 suppresses IL-1β-induced chondrocyte injury via inhibiting the NF-κB pathway.
Transdifferentiation of human male germline stem cells to hepatocytes in vivo via the transplantation under renal capsules.
Calycosin attenuates triglyceride accumulation and hepatic fibrosis in murine model of non-alcoholic steatohepatitis via activating farnesoid X receptor.
Single tumor-initiating cells evade immune clearance by recruiting type II macrophages.
Ontogeny, aging, and gender-related changes in hepatic multidrug resistant protein genes in rats.
Altered Expression of TXNIP in the peripheral leukocytes of patients with coronary atherosclerotic heart disease.
Effects of polysaccharide from Physalis alkekengi var. francheti on liver injury and intestinal microflora in type-2 diabetic mice.
Induction of autophagy by an oleanolic acid derivative, SZC017, promotes ROS-dependent apoptosis through Akt and JAK2/STAT3 signaling pathway in human lung cancer cells.
Glucose potentiates β-cell function by inducing Tph1 expression in rat islets.
POSH participates in epileptogenesis by increasing the surface expression of the NMDA receptor: a promising therapeutic target for epilepsy.
Regulation of AMH by oocyte-specific growth factors in human primary cumulus cells.
Effects of dimethyl carbonate-induced autophagic activation on follicular development in the mouse ovary.
MicroRNA-30e Functions as a Tumor Suppressor in Cervical Carcinoma Cells through Targeting GALNT7.
Piperlongumine suppresses bladder cancer invasion via inhibiting epithelial mesenchymal transition and F-actin reorganization.
Salvianolic acid B protects against lipopolysaccharide-induced behavioral deficits and neuroinflammatory response: involvement of autophagy and NLRP3 inflammasome.
Rho/ROCK Pathway Regulates Migration and Invasion of Esophageal Squamous Cell Carcinoma by Regulating Caveolin-1.
CAPE-pNO(2) ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.
Synergistic inhibition of tumor growth by combination treatment with drugs against different subpopulations of glioblastoma cells.
Discovery of a Small-Molecule Bromodomain-Containing Protein 4 (BRD4) Inhibitor That Induces AMP-Activated Protein Kinase-Modulated Autophagy-Associated Cell Death in Breast Cancer.
Cadherin 6 is activated by Epstein-Barr virus LMP1 to mediate EMT and metastasis as an interplay node of multiple pathways in nasopharyngeal carcinoma.
Ultrasound reverses chemoresistance in breast cancer stem cell like cells by altering ABCG2 expression.
Indomethacin-based stimuli-responsive micelles combined with paclitaxel to overcome multidrug resistance.
De novo, deleterious sequence variants that alter the transcriptional activity of the homeoprotein PBX1 are associated with intellectual disability and pleiotropic developmental defects.
Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells.
Adeno-associated virus 9-mediated Cdk5 inhibitory peptide reverses pathologic changes and behavioral deficits in the Alzheimer's disease mouse model.
Effect of GAPT extract on expression of tau protein and its phosphorylation related enzymes in hippocampal neurons of APPV717I transgenic mice.
Ubiquitin C-terminal hydrolase-L3 promotes interferon antiviral activity by stabilizing type I-interferon receptor.
Palbociclib induces activation of AMPK and inhibits hepatocellular carcinoma in a CDK4/6-independent manner.
NFATc3 mediates the sensitivity of gastric cancer cells to arsenic sulfide.
Apoptosis pattern and alterations of expression of apoptosis-related factors of supporting cells in Kölliker's organ in vivo in early stage after birth in rats.
Enteric dysbiosis-linked gut barrier disruption triggers early renal injury induced by chronic high salt feeding in mice.
Structure-based virtual screening and optimization of modulators targeting Hsp90-Cdc37 interaction.
Exogenous H(2)S facilitating ubiquitin aggregates clearance via autophagy attenuates type 2 diabetes-induced cardiomyopathy.
High expression of RBM8A predicts poor patient prognosis and promotes tumor progression in hepatocellular carcinoma.
Upregulated unique long 16 binding protein 1 detected in preeclamptic placenta affects human extravillous trophoblast cell line (HTR-8/SVneo) invasion by modulating the function of uterine natural killer cells.
Endogenous Stem Cells Were Recruited by Defocused Low-Energy Shock Wave in Treating Diabetic Bladder Dysfunction.
Autoinhibition of Dishevelled protein regulated by its extreme C terminus plays a distinct role in Wnt/β-catenin and Wnt/planar cell polarity (PCP) signaling pathways.
A novel glutaminase inhibitor-968 inhibits the migration and proliferation of non-small cell lung cancer cells by targeting EGFR/ERK signaling pathway.
Paper/PMMA Hybrid 3D Cell Culture Microfluidic Platform for the Study of Cellular Crosstalk.
Tenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicity.
Discovery of a small molecule targeting ULK1-modulated cell death of triple negative breast cancer in vitro and in vivo.
The role of TGF-β-activated kinase 1 in db/db mice and high glucose-induced macrophage.
B7-H4 expression in human infiltrating ductal carcinoma‑associated macrophages.
Interleukin-11 promotes epithelial-mesenchymal transition in anaplastic thyroid carcinoma cells through PI3K/Akt/GSK3β signaling pathway activation.
Functional characterization of hepatitis B virus core promoter mutants revealed transcriptional interference among co-terminal viral mRNAs.
Effect of Polygonatum odoratum extract on human breast cancer MDA-MB-231 cell proliferation and apoptosis.
Afamin promotes glucose metabolism in papillary thyroid carcinoma.
MicroRNA-181b suppresses TAG via target IRS2 and regulating multiple genes in the Hippo pathway.
HSPB1 deficiency sensitizes melanoma cells to hyperthermia induced cell death.
A comparison of incidences of bladder neck contracture of 80- versus 180-W GreenLight laser photoselective vaporization of benign prostatic hyperplasia.
Ubiquitin-dependent Turnover of Adenosine Deaminase Acting on RNA 1 (ADAR1) Is Required for Efficient Antiviral Activity of Type I Interferon.
A novel transgenic mouse model of lysosomal storage disorder.
Foxo3b but not Foxo3a activates cyp19a1a in Epinephelus coioides.
Valsartan Attenuates KIR2.1 by Downregulating the Th1 Immune Response in Rats Following Myocardial Infarction.
Human epithelial-type ovarian tumour marker beta-2-microglobulin is regulated by the TGF-β signaling pathway.
AMPK activation protects cells from oxidative stress-induced senescence via autophagic flux restoration and intracellular NAD(+) elevation.
Pancreatic cancer risk variant in LINC00673 creates a miR-1231 binding site and interferes with PTPN11 degradation.
Deubiquitinase USP2a Sustains Interferons Antiviral Activity by Restricting Ubiquitination of Activated STAT1 in the Nucleus.
Homologous recombination-dependent repair of telomeric DSBs in proliferating human cells.
Blockade of TGF-β-activated kinase 1 prevents advanced glycation end products-induced inflammatory response in macrophages.
The PLC/PKC/Ras/MEK/Kv channel pathway is involved in uncarboxylated osteocalcin-regulated insulin secretion in rats.
Nuclear PTEN interferes with binding of Ku70 at double-strand breaks through post-translational poly(ADP-ribosyl)ation.
Berberine increases adipose triglyceride lipase in 3T3-L1 adipocytes through the AMPK pathway.
Novel Tetrahydropyrido[4,3-d]pyrimidines as Potent Inhibitors of Chaperone Heat Shock Protein 90.
Senescence: novel insight into DLX3 mutations leading to enhanced bone formation in Tricho-Dento-Osseous syndrome.
H2O2 treatment or serum deprivation induces autophagy and apoptosis in naked mole-rat skin fibroblasts by inhibiting the PI3K/Akt signaling pathway.
Chronic stress and excessive glucocorticoid exposure both lead to altered Neuregulin-1/ErbB signaling in rat myocardium.
YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression.
Enhanced SLC34A2 in breast cancer stem cell-like cells induces chemotherapeutic resistance to doxorubicin via SLC34A2-Bmi1-ABCC5 signaling.
Protective effect of melatonin on myenteric neuron damage in experimental colitis in rats.
Arsenic sulfide, the main component of realgar, a traditional Chinese medicine, induces apoptosis of gastric cancer cells in vitro and in vivo.
Cardiac microvascular barrier function mediates the protection of Tongxinluo against myocardial ischemia/reperfusion injury.
Elevated GAPDH expression is associated with the proliferation and invasion of lung and esophageal squamous cell carcinomas.
Gabarapl1 mediates androgen-regulated autophagy in prostate cancer.
MiR-101 sensitizes human nasopharyngeal carcinoma cells to radiation by targeting stathmin 1.
Formaldehyde exposure induces autophagy in testicular tissues of adult male rats.
Astrocyte elevated gene-1 promotes progression of cervical squamous cell carcinoma by inducing epithelial-mesenchymal transition via Wnt signaling.
MiR-200c inhibits autophagy and enhances radiosensitivity in breast cancer cells by targeting UBQLN1.
G-protein coupled receptor 34 activates Erk and phosphatidylinositol 3-kinase/Akt pathways and functions as alternative pathway to mediate p185Bcr-Abl-induced transformation and leukemogenesis.
8-p-Hdroxybenzoyl Tovarol Induces Paraptosis Like Cell Death and Protective Autophagy in Human Cervical Cancer HeLa Cells.
Annexin A3 as a potential target for immunotherapy of liver cancer stem-like cells.
Inhibition of JNK3 promotes apoptosis induced by BH3 mimetic S1 in chemoresistant human ovarian cancer cells.
Decreased expression of mucin-1 in endometriosis endometrium correlated with progesterone receptor B involved in infertility.
Tolerance to endoplasmic reticulum stress mediates cisplatin resistance in human ovarian cancer cells by maintaining endoplasmic reticulum and mitochondrial homeostasis.
IFIT5 positively regulates NF-κB signaling through synergizing the recruitment of IκB kinase (IKK) to TGF-β-activated kinase 1 (TAK1).
Mitophagy in APPsw/PS1dE9 transgenic mice and APPsw stably expressing in HEK293 cells.
G1/S Cell Cycle Checkpoint Dysfunction in Lymphoblasts from Sporadic Parkinson's Disease Patients.
Lentivirus vector-mediated gene transduction of CNGRC peptide in rat adipose stem cells.
Directional Plk1 inhibition-driven cell cycle interruption using amphiphilic thin-coated peptide-lanthanide upconversion nanomaterials as in vivo tumor suppressors.
Neuropilin-1 promotes epithelial-to-mesenchymal transition by stimulating nuclear factor-kappa B and is associated with poor prognosis in human oral squamous cell carcinoma.
Altered expression of hypoxia-inducible factor-1α (HIF-1α) and its regulatory genes in gastric cancer tissues.
Proteomics approaches for identification of tumor relevant protein targets in pulmonary squamous cell carcinoma by 2D-DIGE-MS.
The association of HMGB1 gene with the prognosis of HCC.
Tetramethylpyrazine ameliorates high glucose-induced endothelial dysfunction by increasing mitochondrial biogenesis.
Prognostic value of myeloid differentiation primary response 88 and Toll-like receptor 4 in breast cancer patients.
Elevated MiR-222-3p promotes proliferation and invasion of endometrial carcinoma via targeting ERα.
Matrix metalloproteinase 3 promotes cellular anti-dengue virus response via interaction with transcription factor NFκB in cell nucleus.
Cytotoxicity induced by nanobacteria and nanohydroxyapatites in human choriocarcinoma cells.
PNMA1 promotes cell growth in human pancreatic ductal adenocarcinoma.
mTOR inhibitor AZD8055 inhibits proliferation and induces apoptosis in laryngeal carcinoma.
Involvement of TLR4 in oxidized LDL/β2GPI/anti-β2GPI-induced transformation of macrophages to foam cells.
Ganoderma lucidum polysaccharides target a Fas/caspase dependent pathway to induce apoptosis in human colon cancer cells.
Atorvastatin induces autophagy of mesenchymal stem cells under hypoxia and serum deprivation conditions by activating the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway.
Geniposide and its iridoid analogs exhibit antinociception by acting at the spinal GLP-1 receptors.
Cryopreserved mouse fetal liver stromal cells treated with mitomycin C are able to support the growth of human embryonic stem cells.
USP33, a new player in lung cancer, mediates Slit-Robo signaling.
Neuroprotective role of BNIP3 under oxidative stress through autophagy in neuroblastoma cells.
Dysregulation of vitamin D metabolism in the brain and myocardium of rats following prolonged exposure to dexamethasone.
In vitro and in vivo protection against enterovirus 71 by an antisense phosphorothioate oligonucleotide.
Lipoxin A4 methyl ester ameliorates cognitive deficits induced by chronic cerebral hypoperfusion through activating ERK/Nrf2 signaling pathway in rats.
Direct interaction of 14-3-3ζ with ezrin promotes cell migration by regulating the formation of membrane ruffle.
Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology.
Bone marrow mesenchymal stem cells repair spinal cord ischemia/reperfusion injury by promoting axonal growth and anti-autophagy.
A central role for TRPS1 in the control of cell cycle and cancer development.
Cationic poly(amidoamine) dendrimers induced cyto-protective autophagy in hepatocellular carcinoma cells.
Ezrin is required for epithelial-mesenchymal transition induced by TGF-β1 in A549 cells.
Novel microRNA-like viral small regulatory RNAs arising during human hepatitis A virus infection.
Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.
Chronic stress causes neuroendocrine-immune disturbances without affecting renal vitamin D metabolism in rats.
MicroRNA-145 inhibits cell proliferation by directly targeting ADAM17 in hepatocellular carcinoma.
Toxic effects of levofloxacin on rat annulus fibrosus cells: an in-vitro study.
Cholesterol-conjugated let-7a mimics: antitumor efficacy on hepatocellular carcinoma in vitro and in a preclinical orthotopic xenograft model of systemic therapy.
Phosphatidylinositol 3-kinase CB association with preoperative radiotherapy response in rectal adenocarcinoma.
Levels of human replication factor C4, a clamp loader, correlate with tumor progression and predict the prognosis for colorectal cancer.
Curcumin improves the integrity of blood-spinal cord barrier after compressive spinal cord injury in rats.
The sodium channel β1 subunit mediates outgrowth of neurite-like processes on breast cancer cells and promotes tumour growth and metastasis.
17β-Estradiol protects against apoptosis induced by levofloxacin in rat nucleus pulposus cells by upregulating integrin α2β1.
Nitro-oleic acid downregulates lipoprotein-associated phospholipase A2 expression via the p42/p44 MAPK and NFκB pathways.
Microcystin-LR stabilizes c-myc protein by inhibiting protein phosphatase 2A in HEK293 cells.
Chemical characterization and antitumor activities of polysaccharide extracted from Ganoderma lucidum.
A caspase-dependent pathway is involved in Wnt/β-catenin signaling promoted apoptosis in Bacillus Calmette-Guerin infected RAW264.7 macrophages.
HMG-CoA reductase is negatively associated with PCV2 infection and PCV2-induced apoptotic cell death.
Downregulation of p16(ink4a) inhibits cell proliferation and induces G1 cell cycle arrest in cervical cancer cells.
Zebrafish Cacna1fa is required for cone photoreceptor function and synaptic ribbon formation.
TNF-α promotes early atherosclerosis by increasing transcytosis of LDL across endothelial cells: crosstalk between NF-κB and PPAR-γ.
Effects of natural mineral-rich water consumption on the expression of sirtuin 1 and angiogenic factors in the erectile tissue of rats with fructose-induced metabolic syndrome.
Ruthenium(II) polypyridyl complexes: cellular uptake, cell image and apoptosis of HeLa cancer cells induced by double targets.
Lactobacillus casei reduces susceptibility to type 2 diabetes via microbiota-mediated body chloride ion influx.
Nanoscale chromatin profiling of gastric adenocarcinoma reveals cancer-associated cryptic promoters and somatically acquired regulatory elements.
Chondroprotective effects and multi-target mechanisms of Icariin in IL-1 beta-induced human SW 1353 chondrosarcoma cells and a rat osteoarthritis model.
Protection of ischemic post conditioning against transient focal ischemia-induced brain damage is associated with inhibition of neuroinflammation via modulation of TLR2 and TLR4 pathways.
Expression of SPRR3 is associated with tumor cell proliferation and invasion in glioblastoma multiforme.
MiR-451 increases radiosensitivity of nasopharyngeal carcinoma cells by targeting ras-related protein 14 (RAB14).
Fluoride affects calcium homeostasis and osteogenic transcription factor expressions through L-type calcium channels in osteoblast cell line.
MicroRNA-15b promotes neurogenesis and inhibits neural progenitor proliferation by directly repressing TET3 during early neocortical development.
Lentiviral vector-mediated RBM5 overexpression downregulates EGFR expression in human non-small cell lung cancer cells.
Blocking autophagy enhanced cytotoxicity induced by recombinant human arginase in triple-negative breast cancer cells.
The expression level of TRAF1 in human gastric mucosa is related to virulence genotypes of Helicobacter pylori.
Reversal of multidrug resistance in vitro and in vivo by 5-N-formylardeemin, a new ardeemin derivative.
oxLDL/β2GPI/anti-β2GPI complex induced macrophage differentiation to foam cell involving TLR4/NF-kappa B signal transduction pathway.
Anthocyanin-rich fractions from red raspberries attenuate inflammation in both RAW264.7 macrophages and a mouse model of colitis.
The crucial role of Atg5 in cortical neurogenesis during early brain development.
si-DNMT1 restore tumor suppressor genes expression through the reversal of DNA hypermethylation in cholangiocarcinoma.
NLRP3 deficiency ameliorates neurovascular damage in experimental ischemic stroke.
A synergic role of caspase-6 and caspase-3 in Tau truncation at D421 induced by H2O 2.
miR-200c inhibits metastasis of breast cancer cells by targeting HMGB1.
Epigallocatechin-3-gallate inhibits TF and TNF-α expression induced by the anti-β2GPI/β2GPI complex in human THP-1 cells.
Association analysis of UGT1A genotype and haplotype with SN-38 glucuronidation in human livers.
Activation of spinal glucagon-like peptide-1 receptors specifically suppresses pain hypersensitivity.
Ezh2 regulates adult hippocampal neurogenesis and memory.
Ubiquitin B in cervical cancer: critical for the maintenance of cancer stem-like cell characters.
Simvastatin alleviates hyperpermeability of glomerular endothelial cells in early-stage diabetic nephropathy by inhibition of RhoA/ROCK1.
NOD2 deficiency protects against cardiac remodeling after myocardial infarction in mice.
Scutellarin attenuates hypertension-induced expression of brain Toll-like receptor 4/nuclear factor kappa B.
Anti-β2GPI/β2GPI stimulates activation of THP-1 cells through TLR4/MD-2/MyD88 and NF-κB signaling pathways.
Overexpression of 4EBP1, p70S6K, Akt1 or Akt2 differentially promotes Coxsackievirus B3-induced apoptosis in HeLa cells.
L-3-n-butylphthalide protects against vascular dementia via activation of the Akt kinase pathway.
Specific deletion of Cdc42 does not affect meiotic spindle organization/migration and homologous chromosome segregation but disrupts polarity establishment and cytokinesis in mouse oocytes.
Nucleoside analog inhibits microRNA-214 through targeting heat-shock factor 1 in human epithelial ovarian cancer.
Astragaloside IV attenuates inflammatory cytokines by inhibiting TLR4/NF-кB signaling pathway in isoproterenol-induced myocardial hypertrophy.
Identification and analysis of glycogen synthase kinase 3 beta1 interactome.
Concurrent blockade of NF-κB and Akt pathways potentiates cisplatin's antitumor activity in vivo.
Anti-inflammatory mechanism of taurine against ischemic stroke is related to down-regulation of PARP and NF-κB.
Surgery upregulates high mobility group box-1 and disrupts the blood-brain barrier causing cognitive dysfunction in aged rats.
Regulation of fibroblast growth factor-2 expression and cell cycle progression by an endogenous antisense RNA.
Rosuvastatin treatment activates JAK-STAT pathway and increases efficacy of allogeneic mesenchymal stem cell transplantation in infarcted hearts.
Involvement of IRAKs and TRAFs in anti-β₂GPI/β₂GPI-induced tissue factor expression in THP-1 cells.
Atorvastatin prevents mesenchymal stem cells from hypoxia and serum-free injury through activating AMP-activated protein kinase.
Lentiviral-mediated siRNA targeted against osteopontin suppresses the growth and metastasis of gastric cancer cells.
Perturbation of survivin expression affects chromosome alignment and spindle checkpoint in mouse oocyte meiotic maturation.
[Effects of paclitaxel and gefitinib on the proliferation and cell cycle of human lung adenocarcinoma cell SPC-A1.].
Chen Y, Shen J, Yuan M, Li H, Li Y, Zheng S, Han B, Zhang C, Liu S, Sun Q, Wu J
Journal of advanced research 2025 Jan;67:331-348
Journal of advanced research 2025 Jan;67:331-348
TMEM43 promotes the development of hepatocellular carcinoma by activating VDAC1 through USP7 deubiquitination.
Zhang N, Wang F, Yang X, Wang Q, Chang R, Zhu L, Feitelson MA, Chen Z
Translational gastroenterology and hepatology 2024;9:9
Translational gastroenterology and hepatology 2024;9:9
Radix Bupleuri-Radix Paeoniae Alba Inhibits the Development of Hepatocellular Carcinoma through Activation of the PTEN/PD-L1 Axis within the Immune Microenvironment.
Zhang F, Zhou K, Yuan W, Sun K
Nutrition and cancer 2024;76(1):63-79
Nutrition and cancer 2024;76(1):63-79
Inhibition of IGF2BP1 attenuates the progression of endometriosis through PTBP1.
Su Y, Tian W, Cheng L, Yin L, He X, Wei X
Folia histochemica et cytobiologica 2024;62(1):25-36
Folia histochemica et cytobiologica 2024;62(1):25-36
Hsa_circ_0008833 promotes COPD progression via inducing pyroptosis in bronchial epithelial cells.
Xie T, Yang Z, Xian S, Lin Q, Huang L, Ding Y
Experimental lung research 2024;50(1):1-14
Experimental lung research 2024;50(1):1-14
POMC Neuron BBSome Regulation of Body Weight is Independent of its Ciliary Function.
Guo DF, Williams PA, Laule C, Seaby C, Zhang Q, Sheffield VC, Rahmouni K
Function (Oxford, England) 2024;5(1):zqad070
Function (Oxford, England) 2024;5(1):zqad070
ABCF1/CXCL12/CXCR4 Enhances Glioblastoma Cell Proliferation, Migration, and Invasion by Activating the PI3K/AKT Signal Pathway.
Yin X, Xia K, Peng S, Tan B, Huang Y, Wang M, He M
Developmental neuroscience 2024;46(3):210-220
Developmental neuroscience 2024;46(3):210-220
Therapeutic potential of HUC-MSC-exos primed with IFN-γ against LPS-induced acute lung injury.
Wang C, Jiang C, Yang Y, Xi C, Yin Y, Wu H, Qian C
Iranian journal of basic medical sciences 2024;27(3):375-382
Iranian journal of basic medical sciences 2024;27(3):375-382
Apigenin targets fetuin-A to ameliorate obesity-induced insulin resistance.
Hsu MC, Chen CH, Wang MC, Chen WH, Hu PA, Guo BC, Chang RW, Wang CH, Lee TS
International journal of biological sciences 2024;20(5):1563-1577
International journal of biological sciences 2024;20(5):1563-1577
HNF4A-Bridging the Gap Between Intestinal Metaplasia and Gastric Cancer.
Zhao Y, Tang H, Xu J, Sun F, Zhao Y, Li Y
Evolutionary bioinformatics online 2024;20:11769343241249017
Evolutionary bioinformatics online 2024;20:11769343241249017
Trilobatin ameliorates dextran sulfate sodium-induced ulcerative colitis in mice via the NF-κB pathway and alterations in gut microbiota.
Wang N, Li Z, Cao L, Cui Z
PloS one 2024;19(6):e0305926
PloS one 2024;19(6):e0305926
Echinatin attenuates acute lung injury and inflammatory responses via TAK1-MAPK/NF-κB and Keap1-Nrf2-HO-1 signaling pathways in macrophages.
Luo L, Wang H, Xiong J, Chen X, Shen X, Zhang H
PloS one 2024;19(5):e0303556
PloS one 2024;19(5):e0303556
Comprehensive analysis and validation reveal DEPDC1 as a potential diagnostic biomarker associated with tumor immunity in non-small-cell lung cancer.
Lv M, Li X, Yin Z, Yang H, Zhou B
PloS one 2024;19(4):e0294227
PloS one 2024;19(4):e0294227
A comparative study of apoptosis, pyroptosis, necroptosis, and PANoptosis components in mouse and human cells.
Choudhury SM, Sarkar R, Karki R, Kanneganti TD
PloS one 2024;19(2):e0299577
PloS one 2024;19(2):e0299577
Mesencephalic Astrocyte-derived Neurotrophic Factor Supports Hepatitis B Virus-induced Immunotolerance.
Xie H, Deng H, Yang X, Gao X, Yang S, Chen W, Wang Y, Yang N, Yong L, Hou X
Cellular and molecular gastroenterology and hepatology 2024;18(3):101360
Cellular and molecular gastroenterology and hepatology 2024;18(3):101360
Xinfeng Capsule Inhibits Pyroptosis and Ameliorates Myocardial Injury in Rats with Adjuvant Arthritis via the GAS5/miR-21/TLR4 Axis.
Fu W, Cao Y, Liu J, Huang C, Shu K, Zhu N
Drug design, development and therapy 2024;18:2421-2433
Drug design, development and therapy 2024;18:2421-2433
Propofol and Dexmedetomidine Ameliorate Endotoxemia-Associated Encephalopathy via Inhibiting Ferroptosis.
Zhou Y, Yang Y, Yi L, Pan M, Tang W, Duan H
Drug design, development and therapy 2024;18:1349-1368
Drug design, development and therapy 2024;18:1349-1368
DNMT3B Alleviates Liver Steatosis Induced by Chronic Low-grade LPS via Inhibiting CIDEA Expression.
Li Q, Wang W, Duan F, Wang Y, Chen S, Shi K, Xia Y, Li X, Gao Y, Liu G
Cellular and molecular gastroenterology and hepatology 2024;17(1):59-77
Cellular and molecular gastroenterology and hepatology 2024;17(1):59-77
Downregulation of ST6GAL2 Correlates to Liver Inflammation and Predicts Adverse Prognosis in Hepatocellular Carcinoma.
Liu R, Yu X, Cao X, Wang X, Liang Y, Qi W, Ye Y, Zao X
Journal of inflammation research 2024;17:565-580
Journal of inflammation research 2024;17:565-580
Tat-CIRP Peptide Facilitates Frozen Wound Healing by Ameliorating Inflammation and Promoting Angiogenesis.
Li J, Ding J, Wu H, Lu C, Wu J, Luo Q
Journal of inflammation research 2024;17:2205-2215
Journal of inflammation research 2024;17:2205-2215
Maresin-1 Attenuates Sepsis-Associated Acute Kidney Injury via Suppressing Inflammation, Endoplasmic Reticulum Stress and Pyroptosis by Activating the AMPK/SIRT3 Pathway.
Sun M, Wang F, Li H, Li M, Wang Y, Wang C, Zhang Y, Zhang D, Li J, Yao S
Journal of inflammation research 2024;17:1349-1364
Journal of inflammation research 2024;17:1349-1364
MAT2A inhibition suppresses inflammation in Porphyromonas gingivalis-infected human gingival fibroblasts.
Jiang L, Li J, Ji K, Lei L, Li H
Journal of oral microbiology 2024;16(1):2292375
Journal of oral microbiology 2024;16(1):2292375
MiR-15b-3p weakens bicalutamide sensitivity in prostate cancer via targeting KLF2 to suppress ferroptosis.
Zhang C, Yu H, Bai X, Zhou X, Feng Z, Li Y, Peng X, Mei Y, Li L, Gou X, Deng Y, Chen G
Journal of Cancer 2024;15(8):2306-2317
Journal of Cancer 2024;15(8):2306-2317
Cuproptosis-related genes score and its hub gene GCSH: A novel predictor for cholangiocarcinomas prognosis based on RNA seq and experimental analyses.
He R, Li Y, Jiao P, Huang Y, Dong S, Mo L, Jiao X
Journal of Cancer 2024;15(6):1551-1567
Journal of Cancer 2024;15(6):1551-1567
AQP3 Promotes the Invasion and Metastasis in Cervical Cancer by Regulating NOX4-derived H(2)O(2) Activation of Syk/PI3K/Akt Signaling Axis.
Wang Q, Lin B, Wei H, Wang X, Nie X, Shi Y
Journal of Cancer 2024;15(4):1124-1137
Journal of Cancer 2024;15(4):1124-1137
CENPW knockdown inhibits progression of bladder cancer through inducing cell cycle arrest and apoptosis.
Zhang P, Yang Q, Chen X, Chen X, Wang Q, Chen K, An Y, Jiang K, Sun F
Journal of Cancer 2024;15(3):858-870
Journal of Cancer 2024;15(3):858-870
Exploring the biological behavior and underlying mechanism of KITLG in triple-negative breast cancer.
Qin L, Li Y, Huang Y, Tang C, Yang W, Tang Y, Qiu C, Mao M, Li J
Journal of Cancer 2024;15(3):764-775
Journal of Cancer 2024;15(3):764-775
Radiosensitization of Osteosarcoma Cells Using the PARP Inhibitor Olaparib Combined with X-rays or Carbon Ions.
Dong M, Luo H, Liu R, Zhang J, Yang Z, Wang D, Wang Y, Chen J, Ou Y, Zhang Q, Wang X
Journal of Cancer 2024;15(3):699-713
Journal of Cancer 2024;15(3):699-713
Expression and clinical significance of ECHS1 in gastric cancer.
Lu T, Sun L, Fan Q, Yan J, Zhao D, Xu C, Dong F
Journal of Cancer 2024;15(2):418-427
Journal of Cancer 2024;15(2):418-427
Involvement of autophagy in mesaconitine-induced neurotoxicity in HT22 cells revealed through integrated transcriptomic, proteomic, and m6A epitranscriptomic profiling.
Lin X, Zhang J, Wu Z, Shi Y, Chen M, Li M, Hu H, Tian K, Lv X, Li C, Liu Y, Gao X, Yang Q, Chen K, Zhu A
Frontiers in pharmacology 2024;15:1393717
Frontiers in pharmacology 2024;15:1393717
TAK1 inhibition mitigates intracerebral hemorrhage-induced brain injury through reduction of oxidative stress and neuronal pyroptosis via the NRF2 signaling pathway.
Zhao J, Chen C, Ge L, Jiang Z, Hu Z, Yin L
Frontiers in immunology 2024;15:1386780
Frontiers in immunology 2024;15:1386780
PCBP1 interacts with the HTLV-1 Tax oncoprotein to potentiate NF-κB activation.
Su R, Kang X, Niu Y, Zhao T, Wang H
Frontiers in immunology 2024;15:1375168
Frontiers in immunology 2024;15:1375168
Novel prognostic biomarker TBC1D1 is associated with immunotherapy resistance in gliomas.
Song D, Yang Q, Li L, Wei Y, Zhang C, Du H, Ren G, Li H
Frontiers in immunology 2024;15:1372113
Frontiers in immunology 2024;15:1372113
Identification of claudin-2 as a promising biomarker for early diagnosis of pre-diabetes.
Songtao Y, Fangyu L, Jie C, Li Y
Frontiers in pharmacology 2024;15:1370708
Frontiers in pharmacology 2024;15:1370708
A hypoxia-related genes prognostic risk model, and mechanisms of hypoxia contributing to poor prognosis through immune microenvironment and drug resistance in acute myeloid leukemia.
Liu X, Wang L, Kang Q, Feng C, Wang J
Frontiers in pharmacology 2024;15:1339465
Frontiers in pharmacology 2024;15:1339465
Genistein is effective in inhibiting Orf virus infection in vitro by targeting viral RNA polymerase subunit RPO30 protein.
Lv P, Fang Z, Guan J, Lv L, Xu M, Liu X, Li Z, Lan Y, Li Z, Lu H, Song D, He W, Gao F, Wang D, Zhao K
Frontiers in microbiology 2024;15:1336490
Frontiers in microbiology 2024;15:1336490
TRIM56: a promising prognostic immune biomarker for glioma revealed by pan-cancer and single-cell analysis.
Wang B, Wang Z, Li Y, Shang Z, Liu Z, Fan H, Zhan R, Xin T
Frontiers in immunology 2024;15:1327898
Frontiers in immunology 2024;15:1327898
Single-cell RNA sequencing reveals S100a9(hi) macrophages promote the transition from acute inflammation to fibrotic remodeling after myocardial ischemia‒reperfusion.
Shen S, Zhang M, Wang X, Liu Q, Su H, Sun B, Guo Z, Tian B, Gan H, Gong C, Ma L
Theranostics 2024;14(3):1241-1259
Theranostics 2024;14(3):1241-1259
Ginsenoside Rg3 decreases breast cancer stem-like phenotypes through impairing MYC mRNA stability.
Ning JY, Zhang ZH, Zhang J, Liu YM, Li GC, Wang AM, Li Y, Shan X, Wang JH, Zhang X, Zhao Y
American journal of cancer research 2024;14(2):601-615
American journal of cancer research 2024;14(2):601-615
Polydatin ameliorates low-density lipoprotein cholesterol and lipid metabolism by downregulating proprotein convertase subtilisin/kexin type 9 (PCSK9) in triple-negative breast cancer with hyperlipidemia.
Liu M, Zhang Q
American journal of cancer research 2024;14(1):52-72
American journal of cancer research 2024;14(1):52-72
Bioinformatics analysis and experimental verification of TIGD1 in non-small cell lung cancer.
Xia L, Yang Z, Xv M, Wang G, Mao Y, Yang Y, Tang J
Frontiers in medicine 2024;11:1374260
Frontiers in medicine 2024;11:1374260
IGF2BP2 modulates autophagy and serves as a prognostic marker in glioma.
Li N, Deng L, Zhang Y, Tang X, Lei B, Zhang Q
Ibrain 2024 Spring;10(1):19-33
Ibrain 2024 Spring;10(1):19-33
Exosomes Derived from Meningitic Escherichia coli-Infected Brain Microvascular Endothelial Cells Facilitate Astrocyte Activation.
Yang R, Qu X, Zhi S, Wang J, Fu J, Tan C, Chen H, Wang X
Molecular neurobiology 2024 Sep;61(9):7195-7210
Molecular neurobiology 2024 Sep;61(9):7195-7210
Restoration of HMGCS2-mediated ketogenesis alleviates tacrolimus-induced hepatic lipid metabolism disorder.
Li SL, Zhou H, Liu J, Yang J, Jiang L, Yuan HM, Wang MH, Yang KS, Xiang M
Acta pharmacologica Sinica 2024 Sep;45(9):1898-1911
Acta pharmacologica Sinica 2024 Sep;45(9):1898-1911
mtDNA amplifies beryllium sulfate-induced inflammatory responses via the cGAS-STING pathway in 16HBE cells.
Liu X, Jiang T, Jin H, Yan C, Tong Y, Ding J, Li Y, Huang L, Zhang Z
Journal of applied toxicology : JAT 2024 Sep;44(9):1403-1415
Journal of applied toxicology : JAT 2024 Sep;44(9):1403-1415
NOX1 triggers ferroptosis and ferritinophagy, contributes to Parkinson's disease.
Wang H, Mao W, Zhang Y, Feng W, Bai B, Ji B, Chen J, Cheng B, Yan F
Free radical biology & medicine 2024 Sep;222:331-343
Free radical biology & medicine 2024 Sep;222:331-343
Zinc-Mediated Endoplasmic Reticulum Stress and Metallothionein Alleviate Arsenic-Induced Cardiotoxicity in Cyprinus Carpio.
Dong H, Song H, Liu Y, Zou H
Biological trace element research 2024 Sep;202(9):4203-4215
Biological trace element research 2024 Sep;202(9):4203-4215
PRM1201 effectively inhibits colorectal cancer metastasis via shaping gut microbiota and short- chain fatty acids.
Jia R, Shao S, Zhang P, Yuan Y, Rong W, An Z, Lv S, Feng Y, Liu N, Feng Q, Wang Y, Li Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155795
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155795
Notch-Targeted Therapeutic in Colorectal Cancer by Notch1 Attenuation Via Tumor Microenvironment-Responsive Cascade DNA Delivery.
Lu Y, Cao Y, Guo X, Gao Y, Chen X, Zhang Z, Ge Z, Chu D
Advanced healthcare materials 2024 Sep;13(22):e2400797
Advanced healthcare materials 2024 Sep;13(22):e2400797
Knockdown of programmed cell death factor 4 restores erectile function by attenuating apoptosis in rats with bilateral cavernous nerve crush injury.
Ge Y, Xia T, Feng Z, Xi Y, Hu D, Hong Y, Tang B, Wu J, Chen J, Xiao H
Andrology 2024 Sep;12(6):1439-1448
Andrology 2024 Sep;12(6):1439-1448
A novel UVA-associated circUBE2I mediates ferroptosis in HaCaT cells.
Yi P, Huang Y, Zhao X, Qin Z, Zhu D, Liu L, Zheng Y, Feng J, Long M
Photochemistry and photobiology 2024 Sep-Oct;100(5):1365-1377
Photochemistry and photobiology 2024 Sep-Oct;100(5):1365-1377
Metabolomics reveals the implication of acetoacetate and ketogenic diet therapy in radioiodine-refractory differentiated thyroid carcinoma.
Wang J, Xu Q, Xuan Z, Mao Y, Tang X, Yang K, Song F, Zhu X
The oncologist 2024 Sep 6;29(9):e1120-e1131
The oncologist 2024 Sep 6;29(9):e1120-e1131
Reduced levels of MRE11 cause disease phenotypes distinct from ataxia telangiectasia-like disorder.
Hartlerode AJ, Mostafa AM, Orban SK, Benedeck R, Campbell K, Hoenerhoff MJ, Ferguson DO, Sekiguchi JM
Human molecular genetics 2024 Sep 3;33(18):1605-1617
Human molecular genetics 2024 Sep 3;33(18):1605-1617
Tanreqing injection inhibits influenza virus replication by promoting the fusion of autophagosomes with lysosomes: An integrated pharmacological study.
Guo R, Liu H, Su R, Mao Q, Zhao M, Zhang H, Mu J, Zhao N, Wang Y, Hao Y
Journal of ethnopharmacology 2024 Sep 15;331:118159
Journal of ethnopharmacology 2024 Sep 15;331:118159
Harmine inhibits pulmonary fibrosis through regulating DNA damage repair-related genes and activation of TP53-Gadd45α pathway.
Gong Y, Wang J, Pan M, Zhao Y, Zhang H, Zhang F, Liu J, Yang J, Hu J
International immunopharmacology 2024 Sep 10;138:112542
International immunopharmacology 2024 Sep 10;138:112542
Berberine as a potential enhancer for 5-ALA-mediated fluorescence in glioblastoma: increasing detectability of infiltrating glioma stem cells to optimize 5-ALA-guided surgery.
Ohtsuka Y, Suehiro S, Inoue A, Ohnishi T, Nishikawa M, Yamashita D, Yano H, Choudhury ME, Ozaki S, Sampetrean O, Saya H, Watanabe H, Tanaka J, Kunieda T
Journal of neurosurgery 2024 Sep 1;141(3):653-663
Journal of neurosurgery 2024 Sep 1;141(3):653-663
Central role of Sigma-1 receptor in ochratoxin A-induced ferroptosis.
Chen W, Han L, Yang R, Wang H, Yao S, Deng H, Liu S, Zhou Y, Shen XL
Archives of toxicology 2024 Oct;98(10):3323-3336
Archives of toxicology 2024 Oct;98(10):3323-3336
AQP4 Endocytosis-Lysosome Degradation Mediated by MMP-9/β-DG Involved in Diabetes Cognitive Impairment.
Yuan Y, Peng W, Lei J, Zhao Y, Zhao B, Li Y, Wang J, Qu Q
Molecular neurobiology 2024 Oct;61(10):8438-8453
Molecular neurobiology 2024 Oct;61(10):8438-8453
Influenza A Virus PB1-F2 Induces Affective Disorder by Interfering Synaptic Plasticity in Hippocampal Dentate Gyrus.
Wang S, Zhang H, Liu R, Han P, Yang Q, Cheng C, Chen Y, Rong Z, Su C, Li F, Wei G, Zhao M, Yang L
Molecular neurobiology 2024 Oct;61(10):8293-8306
Molecular neurobiology 2024 Oct;61(10):8293-8306
Dexmedetomidine attenuates ferroptosis by Keap1-Nrf2/HO-1 pathway in LPS-induced acute kidney injury.
Luo RR, Yang J, Sun YL, Zhou BY, Zhou SX, Zhang GX, Yang AX
Naunyn-Schmiedeberg's archives of pharmacology 2024 Oct;397(10):7785-7796
Naunyn-Schmiedeberg's archives of pharmacology 2024 Oct;397(10):7785-7796
PTPN7 mediates macrophage-polarization and determines immunotherapy in gliomas: A single-cell sequencing analysis.
Ji X, Cheng J, Su J, Wen R, Zhang Q, Liu G, Peng Y, Mao J
Environmental toxicology 2024 Oct;39(10):4562-4580
Environmental toxicology 2024 Oct;39(10):4562-4580
Circular RNA CircACAP2 regulates temporomandibular joint osteoarthritis via miR-21-5p/PLAG1 axis.
Chen H, Qu Z, Shi T, Zhao H, Huang S, Ma C
Oral diseases 2024 Oct;30(7):4440-4453
Oral diseases 2024 Oct;30(7):4440-4453
Panobinostat sensitizes AraC-resistant AML cells to the combination of azacitidine and venetoclax.
Zhao J, Wu S, Wang D, Edwards H, Thibodeau J, Kim S, Stemmer P, Wang G, Jin J, Savasan S, Taub JW, Ge Y
Biochemical pharmacology 2024 Oct;228:116065
Biochemical pharmacology 2024 Oct;228:116065
Ginkgo Biloba Extract Can Antagonize Subchronic Arsenite Exposure-Induced Hepatocyte Senescence by Inhibiting Oxidative Damage and Inflammation in Rats.
Chen X, Wu F, Chen C, Ren Q, Zhang A
Biological trace element research 2024 Oct;202(10):4596-4604
Biological trace element research 2024 Oct;202(10):4596-4604
Capturing acyl-enzyme intermediates with genetically encoded 2,3-diaminopropionic acid for hydrolase substrate identification.
Luo J, Yu Y, Wang K, He S, Wang L, Liang F, Chin JW, Tang S
Nature protocols 2024 Oct;19(10):2967-2999
Nature protocols 2024 Oct;19(10):2967-2999
LncRNA H19/miR-107 regulates endothelial progenitor cell pyroptosis and promotes flow recovery of lower extremity ischemia through targeting FADD.
Huang L, Ye Y, Sun Y, Zhou Z, Deng T, Liu Y, Wu R, Wang K, Yao C
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167323
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167323
Identification of TACSTD2 as novel therapeutic targets for cisplatin-induced acute kidney injury by multi-omics data integration.
Deng Z, Dong Z, Wang Y, Dai Y, Liu J, Deng F
Human genetics 2024 Oct;143(9-10):1061-1080
Human genetics 2024 Oct;143(9-10):1061-1080
Neutrophil-Mediated Nanozyme Delivery System for Acute Kidney Injury Therapy.
Yang Y, Du J, Gan J, Song X, Shu J, An C, Lu L, Wei H, Che J, Zhao X
Advanced healthcare materials 2024 Oct;13(26):e2401198
Advanced healthcare materials 2024 Oct;13(26):e2401198
Untargeted serum and gastric metabolomics and network pharmacology analysis reveal the superior efficacy of zingiberis rhizoma recens-/euodiae fructus-processed Coptidis Rhizoma on gastric ulcer rats.
Zhang Z, Zheng Y, Zhang B, Wang R, Chen L, Wang Y, Feng W, Zheng X, Li K, Zhou N
Journal of ethnopharmacology 2024 Oct 5;332:118376
Journal of ethnopharmacology 2024 Oct 5;332:118376
Emerging perfluoroalkyl substances retard skeletal growth by accelerating osteoblasts senescence via ferroptosis.
Wang X, Wang K, Mao W, Fan Z, Liu T, Hong R, Chen H, Pan C
Environmental research 2024 Oct 1;258:119483
Environmental research 2024 Oct 1;258:119483
p38 MAPK inhibitor SB202190 suppresses ferroptosis in the glutamate-induced retinal excitotoxicity glaucoma model.
Feng L, Wang C, Zhang C, Zhang W, Zhu W, He Y, Xia Z, Song W
Neural regeneration research 2024 Oct 1;19(10):2299-2309
Neural regeneration research 2024 Oct 1;19(10):2299-2309
Engineered extracellular vesicles enable high-efficient delivery of intracellular therapeutic proteins.
Ma D, Xie A, Lv J, Min X, Zhang X, Zhou Q, Gao D, Wang E, Gao L, Cheng L, Liu S
Protein & cell 2024 Oct 1;15(10):724-743
Protein & cell 2024 Oct 1;15(10):724-743
Metformin attenuates PM(2.5)-induced oxidative stress by inhibiting the AhR/CYP1A1 pathway in proximal renal tubular epithelial cells.
Cui J, Chen W, Zhang D, Lu M, Huang Z, Yi B
Toxicology mechanisms and methods 2024 Nov;34(9):1022-1034
Toxicology mechanisms and methods 2024 Nov;34(9):1022-1034
Activation of autophagy by Citri Reticulatae Semen extract ameliorates amyloid-beta-induced cell death and cognition deficits in Alzheimer's disease.
Tang Y, Wei J, Wang XF, Long T, Xiang X, Qu L, Wang X, Yu C, Xiao X, Hu X, Zeng J, Xu Q, Wu A, Wu J, Qin D, Zhou X, Law BY
Neural regeneration research 2024 Nov 1;19(11):2467-2479
Neural regeneration research 2024 Nov 1;19(11):2467-2479
Gas6/AXL Alleviates Hepatic Ischemia/Reperfusion Injury by Inhibiting Ferroptosis via the PI3K/AKT Pathway.
Zhan M, Liu D, Yao L, Wang W, Zhang R, Xu Y, Wang Z, Yan Q, Fang Q, Du J, Chen L
Transplantation 2024 Nov 1;108(11):e357-e369
Transplantation 2024 Nov 1;108(11):e357-e369
Autophagy-related protein 5 (ATG5) interacts with bone marrow stromal cell antigen 2 (BST2) to stimulate HBV replication through antagonizing the antiviral activity of BST2.
Li Q, Wen W, Wang Y, Gong T, Wang X, Tan Q, Fan B, Xie H, Li Y, Li S, Yang C, Zhou Z, Duan X, Lin W, Chen L
Journal of medical virology 2024 May;96(5):e29659
Journal of medical virology 2024 May;96(5):e29659
The association between endothelial function and autoimmune thyroiditis induced by iodine excess.
Wang D, Li P, Zhou Z, Jin M, Li B, Li F, Shen H
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2024 May;83:127413
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2024 May;83:127413
Excessive linoleic acid induces muscle oxidative stress through 5-lipoxygenase-dependent peroxidation.
Cao X, Guo H, Dai Y, Jiang G, Liu W, Li X, Zhang D, Huang Y, Wang X, Hua H, Wang J, Chen K, Chi C, Liu H
Redox biology 2024 May;71:103096
Redox biology 2024 May;71:103096
Berberine inhibits excessive autophagy and protects myocardium against ischemia/reperfusion injury via the RhoE/AMPK pathway.
Hu F, Hu T, Qiao Y, Huang H, Zhang Z, Huang W, Liu J, Lai S
International journal of molecular medicine 2024 May;53(5)
International journal of molecular medicine 2024 May;53(5)
Butyrate increases methylglyoxal production through regulation of the JAK2/Stat3/Nrf2/Glo1 pathway in castration‑resistant prostate cancer cells.
Hsia YJ, Lin ZM, Zhang T, Chou TC
Oncology reports 2024 May;51(5)
Oncology reports 2024 May;51(5)
Targeting Large-Conductance Calcium-Activated Potassium Channels to Ameliorate Lipopolysaccharide-Induced Depressive-Like Behavior in Mice.
Li G, Hu L, Gu X, Zhu W, Zhen X, Sun X
Neurochemical research 2024 May;49(5):1239-1253
Neurochemical research 2024 May;49(5):1239-1253
Macrophages promote the transition from myocardial ischemia reperfusion injury to cardiac fibrosis in mice through GMCSF/CCL2/CCR2 and phenotype switching.
Shen SC, Xu J, Cheng C, Xiang XJ, Hong BY, Zhang M, Gong C, Ma LK
Acta pharmacologica Sinica 2024 May;45(5):959-974
Acta pharmacologica Sinica 2024 May;45(5):959-974
Mangiferin alleviates diabetic pulmonary fibrosis in mice via inhibiting endothelial-mesenchymal transition through AMPK/FoxO3/SIRT3 axis.
Fu TL, Li GR, Li DH, He RY, Liu BH, Xiong R, Xu CZ, Lu ZL, Song CK, Qiu HL, Wang WJ, Zou SS, Yi K, Li N, Geng Q
Acta pharmacologica Sinica 2024 May;45(5):1002-1018
Acta pharmacologica Sinica 2024 May;45(5):1002-1018
Characteristics of spatial protein expression in the mouse cochlear sensory epithelia: Implications for age-related hearing loss.
Lao H, Zhu Y, Yang M, Wang L, Tang J, Xiong H
Hearing research 2024 May;446:109006
Hearing research 2024 May;446:109006
Colorectal cancer cells secreting DKK4 transform fibroblasts to promote tumour metastasis.
Li X, Chen Y, Lu R, Hu M, Gu L, Huang Q, Meng W, Zhu H, Fan C, Zhou Z, Mo X
Oncogene 2024 May;43(20):1506-1521
Oncogene 2024 May;43(20):1506-1521
Molecular mechanism of quercetin in treating RA-ILD based on network pharmacology, molecular docking, and experimental validation.
Wang J, Wang Z, Zhao Y, Bai L, Wei Y, Huang T, Xu Y, Zhou X
Naunyn-Schmiedeberg's archives of pharmacology 2024 May;397(5):3077-3092
Naunyn-Schmiedeberg's archives of pharmacology 2024 May;397(5):3077-3092
TOPK promotes the development of psoriasis and worenine alleviates psoriasiform dermatitis by inhibiting TOPK activity.
Lu H, Huang Y, Ni X, Ma T, Chang T, Liu M, Li N, Lu P, Yuan P, Liu L, Shi F, Xiao J, Xiao H, Duan Q, Zhu F
Journal of the European Academy of Dermatology and Venereology : JEADV 2024 May;38(5):851-863
Journal of the European Academy of Dermatology and Venereology : JEADV 2024 May;38(5):851-863
4-PBA exerts brain-protective effects against sepsis-associated encephalopathy in a mouse model of sepsis.
Xiong F, Wang C, Lu J, Bai G, Zhou D, Ling J
Experimental neurology 2024 May;375:114738
Experimental neurology 2024 May;375:114738
TSG6-Exo@CS/GP Attenuates Endometrium Fibrosis by Inhibiting Macrophage Activation in a Murine IUA Model.
Sun H, Dong J, Fu Z, Lu X, Chen X, Lei H, Xiao X, Chen S, Lu J, Su D, Xiong Y, Fang Z, Mao J, Chen L, Wang X
Advanced materials (Deerfield Beach, Fla.) 2024 May;36(21):e2308921
Advanced materials (Deerfield Beach, Fla.) 2024 May;36(21):e2308921
SPI1 activates TGF-β1/PI3K/Akt signaling through transcriptional upregulation of FKBP12 to support the mesenchymal phenotype of glioma stem cells.
Song Y, Zhang Y, Wang X, Han X, Shi M, Xu L, Yu J, Zhang L, Han S
Brain pathology (Zurich, Switzerland) 2024 May;34(3):e13217
Brain pathology (Zurich, Switzerland) 2024 May;34(3):e13217
Human umbilical cord mesenchymal stem cell-derived exosomal miR-214-3p regulates the progression of gallbladder cancer by regulating ACLY/GLUT1.
Liu L, Xiao W, Yang Z, Wang Q, Yi J
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2024 May;33(5):499-510
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2024 May;33(5):499-510
Retinoblastoma-associated protein is important for TRIM24-mediated activation of the mTOR signaling pathway through DUSP2 action in prostate cancer.
Ren D, Li W, Zeng R, Liu X, Liang H, Xiong W, Yang C, Jin X
Cell death and differentiation 2024 May;31(5):592-604
Cell death and differentiation 2024 May;31(5):592-604
Electroacupuncture regulates Rab5a-mediating NGF transduction to improve learning and memory ability in the early stage of AD mice.
Li J, Yang M, Dai Y, Guo X, Ding Y, Li X, Zhang S, Xu W, Chen L, Tao J, Liu W
CNS neuroscience & therapeutics 2024 May;30(5):e14743
CNS neuroscience & therapeutics 2024 May;30(5):e14743
Bovine parainfluenza virus type 3 infections induce ER stress-mediated autophagy to facilitate virus replication.
Han Y, Wang C, Bai C, Diao E, Yuan B, Lu K, Dong X, Zhang R, Han B, Liu H, Wang J, Wang X, Xiao S, Yang Z
Veterinary microbiology 2024 May;292:110051
Veterinary microbiology 2024 May;292:110051
Epigenetic regulation by KDM5A mediates the effects of prenatal PM(2.5) exposure on hippocampal development and synaptic integrity through the Shh signaling pathway.
Huang J, Song C, Liu Y, Zhang T, Wang T, Liu X, Yu L
Ecotoxicology and environmental safety 2024 May;276:116311
Ecotoxicology and environmental safety 2024 May;276:116311
Icariin‑curcumol promotes ferroptosis in prostate cancer cells through Nrf2/HO‑1 signaling.
Sheng W, Li B, Sun T, Zhu C, Li Y, Xu W
Experimental and therapeutic medicine 2024 May;27(5):232
Experimental and therapeutic medicine 2024 May;27(5):232
SUMOylation of GMFB regulates its stability and function in retinal pigment epithelial cells under hyperglycemia.
Sun W, Wang J, Liu C, Gao F, Ou Q, Tian H, Xu J, Zhang J, Li J, Xu J, Jia S, Zhang J, Xu G, Huang J, Jin C, Lu L
International journal of biological macromolecules 2024 May;268(Pt 2):131678
International journal of biological macromolecules 2024 May;268(Pt 2):131678
Iridoid glycosides from Morinda officinalis induce lysosomal biogenesis and promote autophagic flux to attenuate oxidative stress.
Wang YY, Ni JC, Zhao YQ, Yang X, Niu ZP, Yang XZ, Dong XX, Zhao YH, Hao XJ, Ding X
Journal of Asian natural products research 2024 May;26(5):562-574
Journal of Asian natural products research 2024 May;26(5):562-574
Circular RNA hsa_circ_0094976 modulates GPR155 to inhibit gastric adenocarcinoma malignant characteristics by targeting miR-223-3p.
Liu L, Li X, Song L, Yang Y, Li B
Pathology, research and practice 2024 May;257:155325
Pathology, research and practice 2024 May;257:155325
TGF-β1 inhibitor P144 protects against benign restenosis after esophageal stenting through TGF-β1/Smads signaling pathway inhibition.
Wu JZ, Zhou C, Liu S, Zhang JX, Yang W, Shi HB, Zhou WZ
Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology 2024 May;25(2):214-222
Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology 2024 May;25(2):214-222
Chemical proteomics reveals the target landscape of 1,000 kinase inhibitors.
Reinecke M, Brear P, Vornholz L, Berger BT, Seefried F, Wilhelm S, Samaras P, Gyenis L, Litchfield DW, Médard G, Müller S, Ruland J, Hyvönen M, Wilhelm M, Kuster B
Nature chemical biology 2024 May;20(5):577-585
Nature chemical biology 2024 May;20(5):577-585
TRIM22 facilitates autophagosome-lysosome fusion by mediating the association of GABARAPs and PLEKHM1.
Heo H, Park H, Lee MS, Kim J, Kim J, Jung SY, Kim SK, Lee S, Chang J
Autophagy 2024 May;20(5):1098-1113
Autophagy 2024 May;20(5):1098-1113
Endorepellin downregulation promotes angiogenesis after experimental traumatic brain injury.
Zhang Q, Jing Y, Gong Q, Cai L, Wang R, Yang D, Wang L, Qu M, Chen H, Tang Y, Tian H, Ding J, Xu Z
Neural regeneration research 2024 May;19(5):1092-1097
Neural regeneration research 2024 May;19(5):1092-1097
Toosendanin induces hepatotoxicity via disrupting LXRα/Lipin1/SREBP1 mediated lipid metabolism.
Chen S, Ni J, Luo L, Lin J, Peng H, Shen F, Huang Z
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 May;187:114631
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 May;187:114631
Human epididymis protein 4, a novel potential biomarker for diagnostic and prognosis monitoring of lung cancer.
Zhang T, Chu L, Tan W, Ye C, Dong H
The clinical respiratory journal 2024 May;18(5):e13774
The clinical respiratory journal 2024 May;18(5):e13774
Novel small molecule DMAMCL induces differentiation in rhabdomyosarcoma by downregulating of DLL1.
Li Q, Chen Y, Chen Y, Hua Z, Gong B, Liu Z, Thiele CJ, Li Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116562
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116562
Protective effect of esculentoside A against myocardial infarction via targeting C-X-C motif chemokine receptor 2.
Gao M, Cai Q, Bian Y, Wang Z, Xu L, Peng J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116529
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116529
Upregulation of ATF4 mediates the cellular adaptation to pharmacologic inhibition of amino acid transporter LAT1 in pancreatic ductal adenocarcinoma cells.
Ma Y, Okuda S, Okanishi H, Xu M, Jin C, Endou H, Ohgaki R, Kanai Y
Journal of pharmacological sciences 2024 May;155(1):14-20
Journal of pharmacological sciences 2024 May;155(1):14-20
Discovery of a novel small-molecule activator of SIRT3 that inhibits cell proliferation and migration by apoptosis and autophagy-dependent cell death pathways in colorectal cancer.
Mou Y, Chen Y, Fan Z, Ye L, Hu B, Han B, Wang G
Bioorganic chemistry 2024 May;146:107327
Bioorganic chemistry 2024 May;146:107327
Riboflavin protects against pancreatic cancer metastasis by targeting TGF-β receptor 1.
Zhao J, Liu X, Jin X, Dong T, Gao X, Wang J, Li Y, Ma E
Bioorganic chemistry 2024 May;146:107274
Bioorganic chemistry 2024 May;146:107274
WTAP-Mediated N6-Methyladenosine of RNAs Facilitate the Pathophysiology of Atopic Dermatitis.
Tan L, Chen X, Yan S, Guo A, Gao L, Zhou L, Zhou Y, Zeng J, Lu J
The Journal of investigative dermatology 2024 May;144(5):1058-1070.e4
The Journal of investigative dermatology 2024 May;144(5):1058-1070.e4
Urolithin A Hijacks ERK1/2-ULK1 Cascade to Improve CD8(+) T Cell Fitness for Antitumor Immunity.
Ma S, Wu Q, Wu W, Tian Y, Zhang J, Chen C, Sheng X, Zhao F, Ding L, Wang T, Zhao L, Xie Y, Wang Y, Yue X, Wu Z, Wei J, Zhang K, Liang X, Gao L, Wang H, Wang G, Li C, Ma C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(18):e2310065
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(18):e2310065
COSA-1 mediated pro-crossover complex formation promotes meiotic crossing over in C. elegans.
Yang Y, Wang N, Liu G, Nan W, Wang B, Gartner A, Zhang H, Hong Y
Nucleic acids research 2024 May 8;52(8):4375-4392
Nucleic acids research 2024 May 8;52(8):4375-4392
Iron (II)-based metal-organic framework nanozyme for boosting tumor ferroptosis through inhibiting DNA damage repair and system Xc().
Xue P, Zhuang H, Bai T, Zeng X, Deng J, Shao S, Yan S
Journal of nanobiotechnology 2024 May 8;22(1):228
Journal of nanobiotechnology 2024 May 8;22(1):228
Aging-induced tRNA(Glu)-derived fragment impairs glutamate biosynthesis by targeting mitochondrial translation-dependent cristae organization.
Li D, Gao X, Ma X, Wang M, Cheng C, Xue T, Gao F, Shen Y, Zhang J, Liu Q
Cell metabolism 2024 May 7;36(5):1059-1075.e9
Cell metabolism 2024 May 7;36(5):1059-1075.e9
Metaplastic regeneration in the mouse stomach requires a reactive oxygen species pathway.
Miao ZF, Sun JX, Huang XZ, Bai S, Pang MJ, Li JY, Chen HY, Tong QY, Ye SY, Wang XY, Hu XH, Li JY, Zou JW, Xu W, Yang JH, Lu X, Mills JC, Wang ZN
Developmental cell 2024 May 6;59(9):1175-1191.e7
Developmental cell 2024 May 6;59(9):1175-1191.e7
Isocitrate dehydrogenase 1 upregulation in urinary extracellular vesicles from proximal tubules of type 2 diabetic rats.
Sei H, Hirade N, Kamiya K, Nakashima F, Yoshitake J, Kano K, Mishiro-Sato E, Kikuchi R, Uchida K, Shibata T
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23688
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23688
Melatonin suppresses atherosclerosis by ferroptosis inhibition via activating NRF2 pathway.
Tao Y, Zhao Q, Lu C, Yong W, Xu M, Wang Z, Leng X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23678
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23678
Senegenin Attenuates Pulmonary Fibrosis by Inhibiting Oxidative-Stress-Induced Epithelial Cell Senescence through Activation of the Sirt1/Pgc-1α Signaling Pathway.
Zeng Q, Luo Y, Sang X, Liao M, Wen B, Hu Z, Sun M, Luo Z, Huang X, Liu W, Tang S
Antioxidants (Basel, Switzerland) 2024 May 31;13(6)
Antioxidants (Basel, Switzerland) 2024 May 31;13(6)
Serum sSelectin-L is an early specific indicator of radiation injury.
Li S, Zhang W, Zhang H, Fan Y, Jia M, Qi Z, Shen L, He S, Wang Z, Wang Q, Li Y
Heliyon 2024 May 30;10(10):e30527
Heliyon 2024 May 30;10(10):e30527
Inhibitory effects of black phosphorus nanosheets on tumor cell proliferation through downregulation of ADIPOQ and downstream signaling pathways.
Liu D, Zhao Q, Tu Z, Zhang S, Deng S, Xiong Z, Zeng J, Wu F, Zhang X, Xing B
Chemico-biological interactions 2024 May 25;395:110994
Chemico-biological interactions 2024 May 25;395:110994
Phosphatidylserine Counteracts the High Stocking Density-Induced Stress Response, Redox Imbalance and Immunosuppression in Fish Megalobrama ambylsephala.
Jiang Y, Liu Z, Zhang L, Liu W, Li H, Li X
Antioxidants (Basel, Switzerland) 2024 May 25;13(6)
Antioxidants (Basel, Switzerland) 2024 May 25;13(6)
Integrated network pharmacology and experimental validation-based approach to reveal the underlying mechanisms and key material basis of Jinhua Qinggan granules against acute lung injury.
Mi Y, Liang Y, Liu Y, Bai Z, Li N, Tan S, Hou Y
Journal of ethnopharmacology 2024 May 23;326:117920
Journal of ethnopharmacology 2024 May 23;326:117920
Gancao decoction attenuates hepatic necroptosis via activating caspase 8 in cholestatic liver injury.
Zou B, Zhang S, Li F, Weng F, Zhao J, Jin J, Yan D, Xu X, Chen G, Liu C, Yao C, Li Y, Qiu F
Journal of ethnopharmacology 2024 May 23;326:117909
Journal of ethnopharmacology 2024 May 23;326:117909
APC/C-regulated CPT1C promotes tumor progression by upregulating the energy supply and accelerating the G1/S transition.
Zhao H, Cheng X, Yan L, Mi F, Wang W, Hu Y, Liu X, Fan Y, Min Q, Wang Y, Zhang W, Wu Q, Zhan Q
Cell communication and signaling : CCS 2024 May 23;22(1):283
Cell communication and signaling : CCS 2024 May 23;22(1):283
Reduction of specific enterocytes from loss of intestinal LGR4 improves lipid metabolism in mice.
Liang Y, Luo C, Sun L, Feng T, Yin W, Zhang Y, Mulholland MW, Zhang W, Yin Y
Nature communications 2024 May 23;15(1):4393
Nature communications 2024 May 23;15(1):4393
Pacidusin B isolated from Phyllanthus acidus triggers ferroptotic cell death in HT1080 cells.
Zhu G, Luo D, Zhao Y, Xiang Z, Chen C, Li N, Hao X, Ding X, Zhang Y, Zhao Y
Natural products and bioprospecting 2024 May 23;14(1):34
Natural products and bioprospecting 2024 May 23;14(1):34
TRIM65 promotes renal cell carcinoma through ubiquitination and degradation of BTG3.
Zhang Q, Li Y, Zhu Q, Xie T, Xiao Y, Zhang F, Li N, Deng K, Xin H, Huang X
Cell death & disease 2024 May 22;15(5):355
Cell death & disease 2024 May 22;15(5):355
Combination treatment with ferroptosis and autophagy inducers significantly inhibit the proliferation and migration of oral squamous cell carcinoma.
Zhang L, Li Z, Ma X, Yang W, Hao Y, Zhang L, Piao S
Biochemical and biophysical research communications 2024 May 21;709:149842
Biochemical and biophysical research communications 2024 May 21;709:149842
Silent information regulator 2 deficiency exacerbates chronic cold exposure-induced colonic injury and p65 activation in mice.
Guo J, Zhang H, Hu H, Zhao T, Ji H, Ma L, Lu J, Yuan J, Xu B
Gene 2024 May 20;907:148276
Gene 2024 May 20;907:148276
Serine/Arginine-Rich Splicing Factor 7 Knockdown Inhibits Aerobic Glycolysis and Growth in HepG2 Cells by Regulating PKM2 Expression.
Shi W, Yao X, Cao X, Fu Y, Wang Y
Current issues in molecular biology 2024 May 20;46(5):5023-5036
Current issues in molecular biology 2024 May 20;46(5):5023-5036
BAP31 Plays an Essential Role in Mouse B Cell Development via Regulation of BCR Signaling.
Zhao B, An F, Hao Z, Zhang W, Wang B
International journal of molecular sciences 2024 May 2;25(9)
International journal of molecular sciences 2024 May 2;25(9)
Porphyromonas gingivalis OMVs promoting endothelial dysfunction via the STING pathway in periodontitis.
Chen Z, Cao Y, Jiang W, Yan Z, Cai G, Ye J, Wang H, Liu L
Oral diseases 2024 May 2;
Oral diseases 2024 May 2;
KAT6A deficiency impairs cognitive functions through suppressing RSPO2/Wnt signaling in hippocampal CA3.
Liu Y, Fan M, Yang J, Mihaljević L, Chen KH, Ye Y, Sun S, Qiu Z
Science advances 2024 May 17;10(20):eadm9326
Science advances 2024 May 17;10(20):eadm9326
FOXC1 regulates endothelial CD98 (LAT1/4F2hc) expression in retinal angiogenesis and blood-retina barrier formation.
Bhakuni T, Norden PR, Ujiie N, Tan C, Lee SK, Tedeschi T, Hsieh YW, Wang Y, Liu T, Fawzi AA, Kume T
Nature communications 2024 May 16;15(1):4097
Nature communications 2024 May 16;15(1):4097
The miR-641-STIM1 and SATB1 axes play important roles in the regulation of the Th17/Treg balance in ITP.
Zhu H, Ruan X, Zhao K, Kuang W, Liu S, Yan W, Fu X, Cheng Z, Li R, Peng H
Scientific reports 2024 May 16;14(1):11243
Scientific reports 2024 May 16;14(1):11243
Alleviative effects of the parthenolide derivative ACT001 on insulin resistance induced by sodium propionate combined with a high-fat diet and its potential mechanisms.
Yu Q, Zuo X, Bai H, Zhang S, Luan J, Zhao Q, Zhao X, Feng X
European journal of pharmacology 2024 May 15;971:176529
European journal of pharmacology 2024 May 15;971:176529
Pyroptosis inhibitors MCC950 and VX-765 mitigate myocardial injury by alleviating oxidative stress, inflammation, and apoptosis in acute myocardial hypoxia.
Ye X, Lin ZJ, Hong GH, Wang ZM, Dou RT, Lin JY, Xie JH, Shen YW
Experimental cell research 2024 May 15;438(2):114061
Experimental cell research 2024 May 15;438(2):114061
Caspase-3/Gasdermin E-mediated pyroptosis contributes to Ricin toxin-induced inflammation.
Xu Y, Dong M, Sun C, Wang Y, Zhao N, Yu K, Lu N, Xu N, Liu W, Wu C
Toxicology letters 2024 May 15;396:19-27
Toxicology letters 2024 May 15;396:19-27
Wine- and stir-frying processing of Cuscutae Semen enhance its ability to alleviate oxidative stress and apoptosis via the Keap 1-Nrf2/HO-1 and PI3K/AKT pathways in H(2)O(2)-challenged KGN human granulosa cell line.
Liang Y, Shi Y, Guo R, Xu C, Fu M, Shen J, Gao X, Li W, Qin K
BMC complementary medicine and therapies 2024 May 15;24(1):189
BMC complementary medicine and therapies 2024 May 15;24(1):189
iTRAQ-based proteomic study on monocyte cell model discovered an association of LAMP2 downregulation with HIV-1 latency.
Yin L, Wang Q, Liu S, Chen J, Zhang Y, Lu L, Lu H, Song Z, Zhang L
Proteome science 2024 May 15;22(1):6
Proteome science 2024 May 15;22(1):6
Mecp2 fine-tunes quiescence exit by targeting nuclear receptors.
Yang J, Zou S, Qiu Z, Lai M, Long Q, Chen H, Lai PL, Zhang S, Rao Z, Xie X, Gong Y, Liu A, Li M, Bai X
eLife 2024 May 15;12
eLife 2024 May 15;12
Dihydroquercetin regulates HIF-1α/AKT/NR2B signalling to improve impaired brain function in rats with metabolic syndrome.
Fu Y, Yuan P, Zeng M, Zhang Q, Hou Y, Gao L, Wei Y, Zheng Y, Feng W, Zheng X
Heliyon 2024 May 15;10(9):e29807
Heliyon 2024 May 15;10(9):e29807
Pseudorabies virus usurps non-muscle myosin heavy chain IIA to dampen viral DNA recognition by cGAS for antagonism of host antiviral innate immunity.
Liu Y, Qin Y, Yang B, Zheng H, Qiao S, Luo Z, Li R
Journal of virology 2024 May 14;98(5):e0048324
Journal of virology 2024 May 14;98(5):e0048324
METTL3 Promotes OSCC Progression by Down-Regulating WEE1 in a m6A-YTHDF2-Dependent Manner.
Su Y, Hu Y, Qu B, Lei R, Guo G
Molecular biotechnology 2024 May 14;
Molecular biotechnology 2024 May 14;
Epigenetic silencing of LDHB promotes hepatocellular carcinoma by remodeling the tumor microenvironment.
Zhang P, Wan Y, Ma J, Gong J, Zhong Z, Cui Y, Zhang H, Da Y, Ma J, Li C, Liu L, Gong T, Tan Y, Zhang C
Cancer immunology, immunotherapy : CII 2024 May 13;73(7):127
Cancer immunology, immunotherapy : CII 2024 May 13;73(7):127
The crosstalk between macrophages and cancer cells potentiates pancreatic cancer cachexia.
Liu M, Ren Y, Zhou Z, Yang J, Shi X, Cai Y, Arreola AX, Luo W, Fung KM, Xu C, Nipp RD, Bronze MS, Zheng L, Li YP, Houchen CW, Zhang Y, Li M
Cancer cell 2024 May 13;42(5):885-903.e4
Cancer cell 2024 May 13;42(5):885-903.e4
Iron promotes ovarian cancer malignancy and advances platinum resistance by enhancing DNA repair via FTH1/FTL/POLQ/RAD51 axis.
Zhang Q, Chen C, Zou X, Wu W, Di Y, Li N, Fu A
Cell death & disease 2024 May 13;15(5):329
Cell death & disease 2024 May 13;15(5):329
MSC-derived exosomal miR-140-3p improves cognitive dysfunction in sepsis-associated encephalopathy by HMGB1 and S-lactoylglutathione metabolism.
Ma Y, She X, Liu Y, Qin X
Communications biology 2024 May 11;7(1):562
Communications biology 2024 May 11;7(1):562
Cepharanthine synergistically promotes methylprednisolone pharmacodynamics against human peripheral blood mononuclear cells possibly via regulation of P-glycoprotein/glucocorticoid receptor translocation.
Xu W, Chen S, Wang X, Min J, Tanaka S, Onda K, Sugiyama K, Yamada H, Hirano T
BMC complementary medicine and therapies 2024 May 11;24(1):186
BMC complementary medicine and therapies 2024 May 11;24(1):186
Glycosides of Buyang Huanwu decoction inhibits inflammation associated with cerebral ischemia-reperfusion via the PINK1/Parkin mitophagy pathway.
Jiao K, Lai Z, Cheng Q, Yang Z, Liao W, Liao Y, Long H, Sun R, Lang T, Shao L, Deng C, She Y
Journal of ethnopharmacology 2024 May 10;325:117766
Journal of ethnopharmacology 2024 May 10;325:117766
Helicobacter pylori disrupts gastric mucosal homeostasis by stimulating macrophages to secrete CCL3.
Wei YF, Li X, Zhao MR, Liu S, Min L, Zhu ST, Zhang ST, Xie SA
Cell communication and signaling : CCS 2024 May 10;22(1):263
Cell communication and signaling : CCS 2024 May 10;22(1):263
Targeting BRD4 with PROTAC degrader ameliorates LPS-induced acute lung injury by inhibiting M1 alveolar macrophage polarization.
Li D, Deng Y, Wen G, Wang L, Shi X, Chen S, Chen R
International immunopharmacology 2024 May 10;132:111991
International immunopharmacology 2024 May 10;132:111991
The E3 ubiquitin ligase TRIM9 regulates synaptic function and actin dynamics in response to netrin-1.
McCormick LE, Evans EB, Barker NK, Herring LE, Diering GH, Gupton SL
Molecular biology of the cell 2024 May 1;35(5):ar67
Molecular biology of the cell 2024 May 1;35(5):ar67
The role of the sensory input intervention in recovery of the motor function in hypoxic ischemic encephalopathy rat model.
Dong J, Dong Y, An L, Wang Y, Li Y, Jin L
Journal of neurophysiology 2024 May 1;131(5):865-871
Journal of neurophysiology 2024 May 1;131(5):865-871
Lrg1 silencing attenuates ischemia-reperfusion renal injury by regulating autophagy and apoptosis through the TGFβ1- Smad1/5 signaling pathway.
Chen J, Zhang Z, Feng L, Liu W, Wang X, Chen H, Zou H
Archives of biochemistry and biophysics 2024 Mar;753:109892
Archives of biochemistry and biophysics 2024 Mar;753:109892
Myelin repair of spinal cord injury in adult mice induced by treadmill training upregulated peroxisome proliferator-activated receptor gamma coactivator 1 alpha.
Su H, Luo H, Wang Y, Zhao Q, Zhang Q, Zhu Y, Pan L, Liu Y, Yang C, Yin Y, Tan B
Glia 2024 Mar;72(3):607-624
Glia 2024 Mar;72(3):607-624
Knockdown of SIK3 in the CA1 Region can Reduce Seizure Susceptibility in Mice by Inhibiting Decreases in GABA(A)R α1 Expression.
Jiang ZF, Xuan LN, Sun XW, Liu SB, Yin J
Molecular neurobiology 2024 Mar;61(3):1404-1416
Molecular neurobiology 2024 Mar;61(3):1404-1416
Involvement of DJ-1 in the pathogenesis of intervertebral disc degeneration via hexokinase 2-mediated mitophagy.
Lin J, Wang L, Wu Y, Xiang Q, Zhao Y, Zheng X, Jiang S, Sun Z, Fan D, Li W
Experimental & molecular medicine 2024 Mar;56(3):747-759
Experimental & molecular medicine 2024 Mar;56(3):747-759
Gene expression analysis of oxidative stress-related genes in the apical, middle, and basal turns of the cochlea.
Yang Y, Chen X, Tian C, Fan B, An X, Liu Z, Li Q, Mi W, Lin Y, Zha D
Gene expression patterns : GEP 2024 Mar;51:119356
Gene expression patterns : GEP 2024 Mar;51:119356
Morphine induces HADHA succinylation, while HADHA desuccinylation alleviates morphine tolerance by influencing autophagy.
Huang Y, Lu S, Chen Y, Feng Y, Lu W
Naunyn-Schmiedeberg's archives of pharmacology 2024 Mar;397(3):1589-1600
Naunyn-Schmiedeberg's archives of pharmacology 2024 Mar;397(3):1589-1600
Lead inhibits microglial cell migration via suppression of store-operated calcium entry.
Tang W, Peng J, Chen L, Yu C, Wang Y, Zou F, Zheng G, Meng X
Toxicology letters 2024 Mar;393:69-77
Toxicology letters 2024 Mar;393:69-77
Melatonin ameliorates PM2.5-induced spermatogenesis disorder by preserving H3K9 methylation and SIRT3.
Liu J, Zhao M, Dong X, Zhang Y, Xue J, Duan J, Sun Z, Zhou X
Environmental toxicology 2024 Mar;39(3):1471-1480
Environmental toxicology 2024 Mar;39(3):1471-1480
Hypothermic machine perfusion reduces donation after circulatory death liver ischemia-reperfusion injury through the SERPINA3-mediated PI3Kδ/Akt pathway.
Peng S, Liang W, Liu Z, Ye S, Peng Z, Zhong Z, Ye Q
Human cell 2024 Mar;37(2):420-434
Human cell 2024 Mar;37(2):420-434
Rab5c promotes RSV and ADV replication by autophagy in respiratory epithelial cells.
Wang X, Cheng J, Shen L, Chen M, Sun K, Li J, Li M, Ma C, Wei L
Virus research 2024 Mar;341:199324
Virus research 2024 Mar;341:199324
40 Hz light flickering promotes sleep through cortical adenosine signaling.
Zhou X, He Y, Xu T, Wu Z, Guo W, Xu X, Liu Y, Zhang Y, Shang H, Huang L, Yao Z, Li Z, Su L, Li Z, Feng T, Zhang S, Monteiro O, Cunha RA, Huang ZL, Zhang K, Li Y, Cai X, Qu J, Chen JF
Cell research 2024 Mar;34(3):214-231
Cell research 2024 Mar;34(3):214-231
Fucoidan suppresses proliferation and epithelial-mesenchymal transition process via Wnt/β-catenin signalling in hemangioma.
Zhu Z, Luo J, Li L, Wang D, Xu Q, Teng J, Zhou J, Sun L, Yu N, Zuo D
Experimental dermatology 2024 Mar;33(3):e15027
Experimental dermatology 2024 Mar;33(3):e15027
Divergent Roles of KLF4 During Primordial Germ Cell Fate Induction from Human Embryonic Stem Cells.
Fang F, Li Z, Zhang X, Huang Q, Lu S, Wang X
Reproductive sciences (Thousand Oaks, Calif.) 2024 Mar;31(3):727-735
Reproductive sciences (Thousand Oaks, Calif.) 2024 Mar;31(3):727-735
Lipid overload-induced RTN3 activation leads to cardiac dysfunction by promoting lipid droplet biogenesis.
Guo D, Zhang M, Qi B, Peng T, Liu M, Li Z, Fu F, Guo Y, Li C, Wang Y, Hu L, Li Y
Cell death and differentiation 2024 Mar;31(3):292-308
Cell death and differentiation 2024 Mar;31(3):292-308
Normobaric hyperoxia alleviates complement C3-mediated synaptic pruning and brain injury after intracerebral hemorrhage.
Wu M, Chen K, Zhao Y, Jiang M, Bao B, Yu W, Chen Z, Yin X
CNS neuroscience & therapeutics 2024 Mar;30(3):e14694
CNS neuroscience & therapeutics 2024 Mar;30(3):e14694
Rasd1 is involved in white matter injury through neuron-oligodendrocyte communication after subarachnoid hemorrhage.
Fu W, Che X, Tan J, Cui S, Ma Y, Xu D, Long H, Yang X, Wen T, He Z
CNS neuroscience & therapeutics 2024 Mar;30(3):e14452
CNS neuroscience & therapeutics 2024 Mar;30(3):e14452
Inhibition of HDAC6 promotes microvascular endothelial cells to phagocytize myelin debris and reduces inflammatory response to accelerate the repair of spinal cord injury.
Wu C, Pan Y, Wang L, Liu M, Tu P, Chen S, Shi L, Yan D, Ma Y, Guo Y
CNS neuroscience & therapeutics 2024 Mar;30(3):e14439
CNS neuroscience & therapeutics 2024 Mar;30(3):e14439
CD8(+) T cell infiltration and proliferation in the brainstem during experimental cerebral malaria.
Wang J, Zhu Q, Shen Y, Liang J, Wang Y, Huang Y, Tong G, Wang X, Zhang N, Yu K, Li Y, Zhao Y
CNS neuroscience & therapeutics 2024 Mar;30(3):e14431
CNS neuroscience & therapeutics 2024 Mar;30(3):e14431
Selective HDAC6 inhibition protects against blood-brain barrier dysfunction after intracerebral hemorrhage.
Peng C, Wang Y, Hu Z, Chen C
CNS neuroscience & therapeutics 2024 Mar;30(3):e14429
CNS neuroscience & therapeutics 2024 Mar;30(3):e14429
Protective Effects of Danmu Extract Syrup on Acute Lung Injury Induced by Lipopolysaccharide in Mice through Endothelial Barrier Repair.
Xu H, Xu SC, Li LY, Wu YH, Tan YF, Chen L, Liu P, Liang CF, He XN, Li YH
Chinese journal of integrative medicine 2024 Mar;30(3):243-250
Chinese journal of integrative medicine 2024 Mar;30(3):243-250
Capnocytophaga gingivalis is a potential tumor promotor in oral cancer.
Zhu W, Shen W, Wang J, Xu Y, Zhai R, Zhang J, Wang M, Wang M, Liu L
Oral diseases 2024 Mar;30(2):353-362
Oral diseases 2024 Mar;30(2):353-362
Blockade of BTLA alone or in combination with PD-1 restores the activation and proliferation of CD8(+) T cells during in vitro infection with NCP BVDV.
Liu Y, Zhao Z, Su S, Li Y, Chen N, He L, Dong M, Xu B, Zhang Z, Zhou Y, Zhu Z
Veterinary microbiology 2024 Mar;290:110004
Veterinary microbiology 2024 Mar;290:110004
African swine fever virus maintains de novo global cellular protein synthesis and inhibits stress granules formation via dephosphorylating eIF2α.
Gao H, Gao X, Liu X, Luo Y, Zhong J, Liu J, Yan L, Wang H, Gong L, Zhang G, Zheng Z, Sun Y
Veterinary microbiology 2024 Mar;290:109988
Veterinary microbiology 2024 Mar;290:109988
A lncRNA Dleu2-encoded peptide relieves autoimmunity by facilitating Smad3-mediated Treg induction.
Tang S, Zhang J, Lou F, Zhou H, Cai X, Wang Z, Sun L, Sun Y, Li X, Fan L, Li Y, Jin X, Deng S, Yin Q, Bai J, Wang H, Wang H
EMBO reports 2024 Mar;25(3):1208-1232
EMBO reports 2024 Mar;25(3):1208-1232
Alpha-Emitter Radium-223 Induces STING-Dependent Pyroptosis to Trigger Robust Antitumor Immunity.
Yang M, Liu H, Lou J, Zhang J, Zuo C, Zhu M, Zhang X, Yin Y, Zhang Y, Qin S, Zhang H, Fan X, Dang Y, Cheng C, Cheng Z, Yu F
Small (Weinheim an der Bergstrasse, Germany) 2024 Mar;20(9):e2307448
Small (Weinheim an der Bergstrasse, Germany) 2024 Mar;20(9):e2307448
A genome-wide CRISPR screening uncovers that TOB1 acts as a key host factor for FMDV infection via both IFN and EGFR mediated pathways.
Peng G, Liu T, Qi X, Wang Y, Ren J, Peng J, Du X, Hu S, Wu S, Zhao Y, Li D, Zheng H
PLoS pathogens 2024 Mar;20(3):e1012104
PLoS pathogens 2024 Mar;20(3):e1012104
A preliminary mechanistic exploration of the effect of leptin on the docetaxel sensitivity of MDA‑MB‑231 triple‑negative breast cancer cells.
Gao S, Ding S, Tang Z
Molecular and clinical oncology 2024 Mar;20(3):24
Molecular and clinical oncology 2024 Mar;20(3):24
STING activation in cardiomyocytes drives hypertrophy-associated heart failure via NF-κB-mediated inflammatory response.
Wang L, Zhang S, Liu H, Gao L, He L, Chen Y, Zhang J, Yang M, He C
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):166997
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):166997
Ramelteon alleviates myocardial ischemia/reperfusion injury (MIRI) through Sirt3--dependent regulation of cardiomyocyte apoptosis.
Yang Z, Xie Y, Li M, Chen W, Zhong C, Ju J, Deng Q, Wang H, Cheng T, Zhang L, Du W, Liang H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116229
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116229
Proteomic Characterization Identifies Clinically Relevant Subgroups of Gastrointestinal Stromal Tumors.
Sun M, Tong Y, Yuan W, Wang Y, Pu Y, Huang W, Lv B, Xu C, Jiang W, Luo R, Fang R, Tang S, Ren L, Wang J, Feng J, Sun C, Shen K, He F, Hou Y, Ding C
Gastroenterology 2024 Mar;166(3):450-465.e33
Gastroenterology 2024 Mar;166(3):450-465.e33
Inhibition of amino acid transporter LAT1 in cancer cells suppresses G0/G1-S transition by downregulating cyclin D1 via p38 MAPK activation.
Zhou X, Ohgaki R, Jin C, Xu M, Okanishi H, Endou H, Kanai Y
Journal of pharmacological sciences 2024 Mar;154(3):182-191
Journal of pharmacological sciences 2024 Mar;154(3):182-191
TOX3 deficiency mitigates hyperglycemia by suppressing hepatic gluconeogenesis through FoxO1.
Liu C, Zheng Y, Hu S, Liang X, Li Y, Yu Z, Liu Y, Bian Y, Man Y, Zhao S, Liu X, Liu H, Huang T, Ma J, Chen ZJ, Zhao H, Zhang Y
Metabolism: clinical and experimental 2024 Mar;152:155766
Metabolism: clinical and experimental 2024 Mar;152:155766
Mucous cell histopathology and label-free quantitative proteomic analysis of skin mucus in fat greenling (Hexagrammos otakii) infected with Vibrio harveyi.
Wei X, Shi Y, Wang S, Liu H, Zhang Z, Yu L, Hua W, Cui D, Chen Y, Li X, Wang W
Fish & shellfish immunology 2024 Mar;146:109398
Fish & shellfish immunology 2024 Mar;146:109398
Design, synthesis, and pharmacological evaluation of novel benzothiazole derivatives targeting LCK in acute lymphoblastic leukemia.
Chen Y, Zhang K, Tan J, Fan Z, Fu Y, Li X, Liu B, Wang G
Bioorganic chemistry 2024 Mar;144:107180
Bioorganic chemistry 2024 Mar;144:107180
Novel compound heterozygous variants in FANCI cause premature ovarian insufficiency.
Cao L, He X, Ren J, Wen C, Guo T, Yang F, Qin Y, Chen ZJ, Zhao S, Yang Y
Human genetics 2024 Mar;143(3):357-369
Human genetics 2024 Mar;143(3):357-369
Tau induces inflammasome activation and microgliosis through acetylating NLRP3.
Zhang L, Gai Y, Liu Y, Meng D, Zeng Y, Luo Y, Zhang H, Wang Z, Yang M, Li Y, Liu Y, Lai Y, Yang J, Wu G, Chen Y, Zhu J, Liu S, Yu T, Zeng J, Wang J, Zhu D, Wang X, Lan X, Liu R
Clinical and translational medicine 2024 Mar;14(3):e1623
Clinical and translational medicine 2024 Mar;14(3):e1623
Hepatic transcriptome discloses the potential targets of Xuefu Zhuyu Decoction ameliorating non-alcoholic fatty liver disease induced by high-fat diet.
Tang H, Wang J, Fang Y, Yin Y, Liu W, Hu Y, Peng J
Journal of traditional and complementary medicine 2024 Mar;14(2):135-147
Journal of traditional and complementary medicine 2024 Mar;14(2):135-147
MBIP promotes ESCC metastasis by activating MAPK pathway.
Ma Y, Hua Y, Yin X, Jiao Y, Xu E, Yan T, Yang J, Zhang L
Cellular signalling 2024 Mar;115:111040
Cellular signalling 2024 Mar;115:111040
Identification of PRDX5 as A Target for The Treatment of Castration-Resistant Prostate Cancer.
Wang R, Mi Y, Ni J, Wang Y, Ding L, Ran X, Sun Q, Tan SY, Koeffler HP, Feng N, Chen YQ
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(9):e2304939
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(9):e2304939
Cfp1 Controls Cardiomyocyte Maturation by Modifying Histone H3K4me3 of Structural, Metabolic, and Contractile Related Genes.
Li C, Zhang Y, Shen J, Bao H, Zhao Y, Li D, Li S, Liu Y, Yang J, Zhou Z, Gao K, Zhao L, Pei Y, Lu Y, Pan Z, Cai B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(11):e2305992
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(11):e2305992
Disrupting PIAS3-mediated SUMOylation of MLK3 ameliorates poststroke neuronal damage and deficits in cognitive and sensorimotor behaviors.
Jiang Y, Hu L, Wang B, Zhang B, Shao M, Meng L, Xu Y, Chen R, Li M, Du C
Cellular and molecular life sciences : CMLS 2024 Mar 8;81(1):119
Cellular and molecular life sciences : CMLS 2024 Mar 8;81(1):119
Polyphyllin B inhibited STAT3/NCOA4 pathway and restored gut microbiota to ameliorate lung tissue injury in cigarette smoke-induced mice.
Wang Q, He Z, Zhu J, Hu M, Yang L, Yang H
BMC biotechnology 2024 Mar 8;24(1):13
BMC biotechnology 2024 Mar 8;24(1):13
Aryl hydrocarbon receptor suppresses STING-mediated type I IFN expression in triple-negative breast cancer.
Martin JC, da Silva Fernandes T, Chaudhry KA, Oshi M, Abrams SI, Takabe K, Rosario SR, Bianchi-Smiraglia A
Scientific reports 2024 Mar 8;14(1):5731
Scientific reports 2024 Mar 8;14(1):5731
High expression of KIFC1 is a poor prognostic biomarker and correlates with TP53 mutation in lung cancer.
Li X, Wang S, Ruan P, Bajinka O, Zhang W
Medicine 2024 Mar 8;103(10):e37286
Medicine 2024 Mar 8;103(10):e37286
Interleukin-22 Contributes to Blood-Brain Barrier Disruption via STAT3/VEGFA Activation in Escherichia coli Meningitis.
Yang R, Chen J, Qu X, Liu H, Wang X, Tan C, Chen H, Wang X
ACS infectious diseases 2024 Mar 8;10(3):988-999
ACS infectious diseases 2024 Mar 8;10(3):988-999
Late-stage modification of complex drug: Base-controlled Pd-catalyzed regioselective synthesis and bioactivity of arylated osimertinibs.
Feng R, Zhen YQ, Wu D, Sun L, Xu JB, Li X, Zhang L, Gao F
Science advances 2024 Mar 8;10(10):eadl0026
Science advances 2024 Mar 8;10(10):eadl0026
Identified S100A9 as a target for diagnosis and treatment of ulcerative colitis by bioinformatics analysis.
Tan L, Li X, Qin H, Zhang Q, Wang J, Chen T, Zhang C, Zhang X, Tan Y
Scientific reports 2024 Mar 6;14(1):5517
Scientific reports 2024 Mar 6;14(1):5517
Hinokitiol protects gastric injury from ethanol exposure via its iron sequestration capacity.
Zhao M, Qiao C, Yang S, Tang Y, Sun W, Sun S, Guo Q, Du F, Zhang N, Ning T, Wu J, Xu J, Li P
European journal of pharmacology 2024 Mar 5;966:176340
European journal of pharmacology 2024 Mar 5;966:176340
Dietary Restriction Improves Perioperative Neurocognitive Disorders by Inhibiting Neuroinflammation and Gut Microbial Dysbiosis.
Ren L, Liang H, Zhu L, Yang X, Zhang H, Sun N, Huang D, Feng J, Wu Y, Xiong L, Ke X, Li M, Zhang A
Neuroscience 2024 Mar 5;540:48-67
Neuroscience 2024 Mar 5;540:48-67
T-2 toxin induces mitochondrial dysfunction in chondrocytes via the p53-cyclophilin D pathway.
Yu FF, Yu SY, Sun L, Zuo J, Luo KT, Wang M, Fu XL, Zhang F, Huang H, Zhou GY, Wang YJ, Ba Y
Journal of hazardous materials 2024 Mar 5;465:133090
Journal of hazardous materials 2024 Mar 5;465:133090
Augmentation of scleral glycolysis promotes myopia through histone lactylation.
Lin X, Lei Y, Pan M, Hu C, Xie B, Wu W, Su J, Li Y, Tan Y, Wei X, Xue Z, Xu R, Di M, Deng H, Liu S, Yang X, Qu J, Chen W, Zhou X, Zhao F
Cell metabolism 2024 Mar 5;36(3):511-525.e7
Cell metabolism 2024 Mar 5;36(3):511-525.e7
Whole genome sequencing analysis of Limosilactobacillus reuteri from the intestinal tract of mice recovering from ulcerative colitis and preliminary study on anti-inflammatory effects of its derived peptides.
Wang Z, Zhang Z, Shi Q, Liu S, Wu Q, Wang Z, Saiding E, Han J, Zhou J, Wang R, Su X
Archives of microbiology 2024 Mar 5;206(4):140
Archives of microbiology 2024 Mar 5;206(4):140
SARS-CoV-2 NSP2 as a Potential Delivery Vehicle for Proteins.
Zheng N, Liu S, Chen J, Xu Y, Cao W, Lin J, Lu G, Zhang G
Molecular pharmaceutics 2024 Mar 4;21(3):1149-1159
Molecular pharmaceutics 2024 Mar 4;21(3):1149-1159
CSNK2A1 confers gemcitabine resistance to pancreatic ductal adenocarcinoma via inducing autophagy.
Liu ZD, Shi YH, Xu QC, Zhao GY, Zhu YQ, Li FX, Ma MJ, Ye JY, Huang XT, Wang XY, Xu X, Wang JQ, Zhao W, Yin XY
Cancer letters 2024 Mar 31;585:216640
Cancer letters 2024 Mar 31;585:216640
WNT2B activates macrophages via NF-κB signaling pathway in inflammatory bowel disease.
Lan L, Huang C, Liu D, Cheng Y, Tang R, Gu J, Geng L, Cheng Y, Gong S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 31;38(6):e23551
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 31;38(6):e23551
PGRN inhibits CD8(+)T cell recruitment and promotes breast cancer progression by up-regulating ICAM-1 on TAM.
Zhou T, Qian H, Zhang D, Fang W, Yao M, Shi H, Chen T, Chai C, Guo B
Cancer immunology, immunotherapy : CII 2024 Mar 30;73(5):76
Cancer immunology, immunotherapy : CII 2024 Mar 30;73(5):76
Pcgf5: An important regulatory factor in early embryonic neural induction.
Yang X, Zhou W, Zhou J, Li A, Zhang C, Fang Z, Wang C, Liu S, Hao A, Zhang M
Heliyon 2024 Mar 30;10(6):e27634
Heliyon 2024 Mar 30;10(6):e27634
Elucidating the role of intrinsic adenosine A1 receptors in acute alcoholism using human-induced pluripotent stem cell-derived hepatocytes.
Nagata T, Huang YG
Bioscience reports 2024 Mar 29;44(3)
Bioscience reports 2024 Mar 29;44(3)
Fisetin Alleviates Inflammation and Oxidative Stress in Deep Vein Thrombosis via MAPK and NRF2 Signaling Pathway.
Liu H, Lu Q
International journal of molecular sciences 2024 Mar 27;25(7)
International journal of molecular sciences 2024 Mar 27;25(7)
The Tumor Microenvironment Mediates the HIF-1α/PD-L1 Pathway to Promote Immune Escape in Colorectal Cancer.
Sun J, Zhao Z, Lu J, An W, Zhang Y, Li W, Yang L
International journal of molecular sciences 2024 Mar 27;25(7)
International journal of molecular sciences 2024 Mar 27;25(7)
Human periodontal ligament stem cell sheets activated by graphene oxide quantum dots repair periodontal bone defects by promoting mitochondrial dynamics dependent osteogenic differentiation.
An N, Yan X, Qiu Q, Zhang Z, Zhang X, Zheng B, Zhao Z, Guo J, Liu Y
Journal of nanobiotechnology 2024 Mar 27;22(1):133
Journal of nanobiotechnology 2024 Mar 27;22(1):133
SRRM2 phase separation drives assembly of nuclear speckle subcompartments.
Zhang M, Gu Z, Guo S, Sun Y, Ma S, Yang S, Guo J, Fang C, Shu L, Ge Y, Chen Z, Wang B
Cell reports 2024 Mar 26;43(3):113827
Cell reports 2024 Mar 26;43(3):113827
Exploring the molecular mechanism of Artemisia rupestris L. for the treatment of hepatocellular carcinoma via PI3K/AKT pathway.
Zhang S, Cai X, Khan GJ, Cheng J, He J, Zhai K, Mao Y
Journal of ethnopharmacology 2024 Mar 25;322:117572
Journal of ethnopharmacology 2024 Mar 25;322:117572
MiR-155-5p improves the insulin sensitivity of trophoblasts by targeting CEBPB in gestational diabetes mellitus.
Zhang H, Jiang Y, Zhu S, Wei L, Zhou X, Gao P, Zhang J, Chen Y, Du Y, Fang C, Su R, Li J, Wang S, Feng L
Placenta 2024 Mar 25;148:1-11
Placenta 2024 Mar 25;148:1-11
Hypoxia-Challenged Pancreatic Adenocarcinoma Cell-Derived Exosomal circR3HCC1L Drives Tumor Growth Via Upregulating PKM2 Through Sequestering miR-873-5p.
Wang L, Zhou S, Ruan Y, Wu X, Zhang X, Li Y, Ying D, Lu Y, Tian Y, Cheng G, Zhang J, Lv K, Zhou X
Molecular biotechnology 2024 Mar 25;
Molecular biotechnology 2024 Mar 25;
A novel microglia-targeting strategy based on nanoparticle-mediated delivery of miR-26a-5p for long-lasting analgesia in chronic pain.
Lu Y, Liu S, Wang P, Guo X, Qin Z, Hou H, Tao T
Journal of nanobiotechnology 2024 Mar 23;22(1):128
Journal of nanobiotechnology 2024 Mar 23;22(1):128
AURKA emerges as a vulnerable target for KEAP1-deficient non-small cell lung cancer by activation of asparagine synthesis.
Deng B, Liu F, Chen N, Li X, Lei J, Chen N, Wu J, Wang X, Lu J, Fang M, Chen A, Zhang Z, He B, Yan M, Zhang Y, Wang Z, Liu Q
Cell death & disease 2024 Mar 23;15(3):233
Cell death & disease 2024 Mar 23;15(3):233
Identification and validation of DHCR7 as a diagnostic biomarker involved in the proliferation and mitochondrial function of breast cancer.
Wang Y, Fan J, Liu Y, Du J, Liang B, Wang H, Song Z
Aging 2024 Mar 22;16(7):5967-5986
Aging 2024 Mar 22;16(7):5967-5986
G-quadruplexes on chromosomal DNA negatively regulates topoisomerase 1 activity.
Liang HT, Yan JY, Yao HJ, Zhang XN, Xing ZM, Liu L, Chen YQ, Li GR, Huang J, He YD, Zheng KW
Nucleic acids research 2024 Mar 21;52(5):2142-2156
Nucleic acids research 2024 Mar 21;52(5):2142-2156
Trimethylamine N-oxide impairs β-cell function and glucose tolerance.
Kong L, Zhao Q, Jiang X, Hu J, Jiang Q, Sheng L, Peng X, Wang S, Chen Y, Wan Y, Hou S, Liu X, Ma C, Li Y, Quan L, Chen L, Cui B, Li P
Nature communications 2024 Mar 21;15(1):2526
Nature communications 2024 Mar 21;15(1):2526
[Activation of α7 nAChR improves white fat homeostasis and promotes beige adipogenesis and thermogenesis in obese mice].
Bao H, Wang S, Lü M, Wang Y, Jiang P, Li X
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2024 Mar 20;44(3):499-506
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2024 Mar 20;44(3):499-506
Bi(2)S(3)/Ti(3)C(2)-TPP nano-heterostructures induced by near-infrared for photodynamic therapy combined with photothermal therapy on hypoxic tumors.
Jiang H, Sun J, Liu F, Zhao Y, Chen X, Dai C, Wen Z
Journal of nanobiotechnology 2024 Mar 20;22(1):123
Journal of nanobiotechnology 2024 Mar 20;22(1):123
Identification and validation of a novel signature based on macrophage marker genes for predicting prognosis and drug response in kidney renal clear cell carcinoma by integrated analysis of single cell and bulk RNA sequencing.
Chen X, Zhang Z, Qin Z, Zhu X, Wang K, Kang L, Li C, Wang H
Aging 2024 Mar 20;16(6):5676-5702
Aging 2024 Mar 20;16(6):5676-5702
Extracellular vesicles secreted from mesenchymal stem cells ameliorate renal ischemia reperfusion injury by delivering miR-100-5p targeting FKBP5/AKT axis.
Chen G, Li X, Zhou X, Li Y, Yu H, Peng X, Bai X, Zhang C, Feng Z, Mei Y, Li L, Liu Y, Gou X, Jiang Y
Scientific reports 2024 Mar 20;14(1):6720
Scientific reports 2024 Mar 20;14(1):6720
Lactobacillus rhamnosus GG ameliorates hyperuricemia in a novel model.
Fu Y, Chen YS, Xia DY, Luo XD, Luo HT, Pan J, Ma WQ, Li JZ, Mo QY, Tu Q, Li MM, Zhao Y, Li Y, Huang YT, Chen ZX, Li ZJ, Bernard L, Dione M, Zhang YM, Miao K, Chen JY, Zhu SS, Ren J, Zhou LJ, Jiang XZ, Chen J, Lin ZP, Chen JP, Ye H, Cao QY, Zhu YW, Yang L, Wang X, Wang WC
NPJ biofilms and microbiomes 2024 Mar 20;10(1):25
NPJ biofilms and microbiomes 2024 Mar 20;10(1):25
Endogenous TDP-43 mislocalization in a novel knock-in mouse model reveals DNA repair impairment, inflammation, and neuronal senescence.
Mitra J, Dharmalingam P, Kodavati M, Guerrero EN, Rao KS, Garruto RM, Hegde ML
Research square 2024 Mar 20;
Research square 2024 Mar 20;
Ubiquitin-specific proteinase 1 stabilizes PRRSV nonstructural protein Nsp1β to promote viral replication by regulating K48 ubiquitination.
Zhai Y, Du Y, Yuan H, Fan S, Chen X, Wang J, He W, Han S, Zhang Y, Hu M, Zhang G, Kong Z, Wan B
Journal of virology 2024 Mar 19;98(3):e0168623
Journal of virology 2024 Mar 19;98(3):e0168623
RBM14 inhibits the replication of porcine epidemic diarrhea virus by recruiting p62 to degrade nucleocapsid protein through the activation of autophagy and interferon pathway.
Wang X, Tong W, Yang X, Zhai H, Qin W, Liu C, Zheng H, Yu H, Tong G, Zhang Z, Kong N, Shan T
Journal of virology 2024 Mar 19;98(3):e0018224
Journal of virology 2024 Mar 19;98(3):e0018224
Deacetylase Sirtuin 1 mitigates type I IFN- and type II IFN-induced signaling and antiviral immunity.
Yu S-S, Tang R-C, Zhang A, Geng S, Yu H, Zhang Y, Sun X-Y, Zhang J
Journal of virology 2024 Mar 19;98(3):e0008824
Journal of virology 2024 Mar 19;98(3):e0008824
ART1 knockdown decreases the IL-6-induced proliferation of colorectal cancer cells.
Lin T, Zhang S, Tang Y, Xiao M, Li M, Gong H, Xie H, Wang Y
BMC cancer 2024 Mar 19;24(1):354
BMC cancer 2024 Mar 19;24(1):354
Pan-cancer analysis of NUP155 and validation of its role in breast cancer cell proliferation, migration, and apoptosis.
Wang ZQ, Wu ZX, Wang ZP, Bao JX, Wu HD, Xu DY, Li HF, Xu YY, Wu RX, Dai XX
BMC cancer 2024 Mar 19;24(1):353
BMC cancer 2024 Mar 19;24(1):353
CircALMS1 Alleviates Pulmonary Microvascular Endothelial Cell Dysfunction in Pulmonary Hypertension.
Hu X, Sun Y, Wang S, Zhao H, Wei Y, Fu J, Huang Y, Wu W, Li J, Liu J, Gong S, Zhao Q, Wang L, Jiang R, Song X, Yuan P
Journal of the American Heart Association 2024 Mar 19;13(6):e031867
Journal of the American Heart Association 2024 Mar 19;13(6):e031867
Loss of Preproinsulin Interaction with Signal Recognition Particle Activates Protein Quality Control, Decreasing mRNA Stability.
Miller SC, Tikhonova EB, Hernandez SM, Dufour JM, Karamyshev AL
Journal of molecular biology 2024 Mar 15;436(6):168492
Journal of molecular biology 2024 Mar 15;436(6):168492
Co-exposure to polystyrene nanoplastics and triclosan induces synergistic cytotoxicity in human KGN granulosa cells by promoting reactive oxygen species accumulation.
Wang W, Zhou C, Ma Z, Zeng L, Wang H, Cheng X, Zhang C, Xue Y, Yuan Y, Li J, Hu L, Huang J, Luo T, Zheng L
Ecotoxicology and environmental safety 2024 Mar 15;273:116121
Ecotoxicology and environmental safety 2024 Mar 15;273:116121
TET2 stabilized by deubiquitinase USP21 ameliorates cigarette smoke-induced apoptosis in airway epithelial cells.
Luo L, Zeng Z, Li T, Liu X, Cui Y, Tao Y, Li Y, Chen Y
iScience 2024 Mar 15;27(3):109252
iScience 2024 Mar 15;27(3):109252
Dietary protein restriction regulates skeletal muscle fiber metabolic characteristics associated with the FGF21-ERK1/2 pathway.
Li S, Zhong H, Wang Z, Chen J, Huang Z, Zou T, You J
iScience 2024 Mar 15;27(3):109249
iScience 2024 Mar 15;27(3):109249
Independent prognostic value of CLDN6 in bladder cancer based on M2 macrophages related signature.
Qi D, Lu Y, Qu H, Dong Y, Jin Q, Sun M, Li Y, Quan C
iScience 2024 Mar 15;27(3):109138
iScience 2024 Mar 15;27(3):109138
The mechanisms and therapeutic potential of clopidogrel in mitigating diabetic cardiomyopathy in db/db mice.
Li B, Zhang Y, Zheng Y, Cai H
iScience 2024 Mar 15;27(3):109134
iScience 2024 Mar 15;27(3):109134
FTO attenuates the cytotoxicity of cisplatin in KGN granulosa cell-like tumour cells by regulating the Hippo/YAP1 signalling pathway.
Wang R, Cheng F, Yang X
Journal of ovarian research 2024 Mar 15;17(1):62
Journal of ovarian research 2024 Mar 15;17(1):62
l-Theanine delays d-galactose-induced senescence by regulating the cell cycle and inhibiting apoptosis in rat intestinal cells.
Xu W, Xiang X, Lin L, Gong ZH, Xiao WJ
Journal of the science of food and agriculture 2024 Mar 15;104(4):2073-2084
Journal of the science of food and agriculture 2024 Mar 15;104(4):2073-2084
L-Theanine alleviates heat stress through modulation of gut microbiota and immunity.
Liu S, Wang B, Lin L, Xu W, Gong ZH, Xiao WJ
Journal of the science of food and agriculture 2024 Mar 15;104(4):2059-2072
Journal of the science of food and agriculture 2024 Mar 15;104(4):2059-2072
GPR39 Agonist TC-G 1008 Promoted Mitochondrial Biogenesis and Improved Antioxidative Capability via CREB/PGC-1α Pathway Following Intracerebral Hemorrhage in Mice.
Zhang Z, Yuan Y, Zhang X, Gu L, Tang Y, Zhao Y, Dai J, Tao Y, Xie Z
Translational stroke research 2024 Mar 15;
Translational stroke research 2024 Mar 15;
Purinergic P2X7 receptor involves in anti-retinal photodamage effects of berberine.
Ye SS, Wang JN, Zhao YF, Dai LS, Zhang JZ, Zuo YQ, Song JT
Purinergic signalling 2024 Mar 15;
Purinergic signalling 2024 Mar 15;
SARS-CoV-2 remodels the Golgi apparatus to facilitate viral assembly and secretion.
Zhang J, Kennedy A, de Melo Jorge DM, Xing L, Reid W, Bui S, Joppich J, Rose M, Ercan S, Tang Q, Tai AW, Wang Y
bioRxiv : the preprint server for biology 2024 Mar 15;
bioRxiv : the preprint server for biology 2024 Mar 15;
MCL1 inhibition: a promising approach to augment the efficacy of sorafenib in NSCLC through ferroptosis induction.
Huang CY, Chen LJ, Chen CS, Wang CY, Hong SY
Cell death discovery 2024 Mar 14;10(1):137
Cell death discovery 2024 Mar 14;10(1):137
HLA-class II restricted TCR targeting human papillomavirus type 18 E7 induces solid tumor remission in mice.
Long J, Chen X, He M, Ou S, Zhao Y, Yan Q, Ma M, Chen J, Qin X, Zhou X, Chu J, Han Y
Nature communications 2024 Mar 13;15(1):2271
Nature communications 2024 Mar 13;15(1):2271
BNC1 deficiency induces mitochondrial dysfunction-triggered spermatogonia apoptosis through the CREB/SIRT1/FOXO3 pathway: the therapeutic potential of nicotinamide riboside and metformin†.
Ni F, Wang F, Li J, Liu Y, Sun X, Chen J, Li J, Zhang Y, Jin J, Ye X, Tu M, Chen J, Chen C, Zhang D
Biology of reproduction 2024 Mar 13;110(3):615-631
Biology of reproduction 2024 Mar 13;110(3):615-631
Sulforaphane Regulates Macrophage M1/M2 Polarization to Attenuate Macrophage-induced Caco-2 Cell Injury in an Inflammatory Environment.
Yi T, Liu Z, Jia H, Liu Q, Peng J
Iranian journal of immunology : IJI 2024 Mar 12;21(1):37-52
Iranian journal of immunology : IJI 2024 Mar 12;21(1):37-52
Cluster of Differentiation-44-Targeting Prussian Blue Nanoparticles Onloaded with Colchicine for Atherosclerotic Plaque Regression in a Mice Model.
Zhu Y, Fang Y, Wang Y, Han D, Liu J, Tian L, Xu M, Wang Y, Cao F
ACS biomaterials science & engineering 2024 Mar 11;10(3):1530-1543
ACS biomaterials science & engineering 2024 Mar 11;10(3):1530-1543
Synergistic effects and molecular mechanisms of DL-3-n-butylphthalide combined with dual antiplatelet therapy in acute ischemic stroke.
Du Y, Li L, Li X, Tan J, Qin Y, Lv Y, Zhai X
International immunopharmacology 2024 Mar 10;129:111592
International immunopharmacology 2024 Mar 10;129:111592
High-frequency repetitive transcranial magnetic stimulation improves depressive-like behaviors in CUMS-induced rats by modulating astrocyte GLT-1 to reduce glutamate toxicity.
Wang X, Zhang F, Niu L, Yan J, Liu H, Wang D, Hui J, Dai H, Song J, Zhang Z
Journal of affective disorders 2024 Mar 1;348:265-274
Journal of affective disorders 2024 Mar 1;348:265-274
Testosterone regulates thymic remodeling by altering metabolic reprogramming in male rats.
Li D, Yao H, Ren Y, Shang J, Han X, Cao X, Song T, Zeng X
General and comparative endocrinology 2024 Mar 1;348:114448
General and comparative endocrinology 2024 Mar 1;348:114448
From inflammation to pyroptosis: Understanding the consequences of cadmium exposure in chicken liver cells.
Li L, Xu H, Wang Y, Zhang Y, Ye R, Li W, Yang J, Wu J, Li J, Jin E, Cao M, Li X, Li S, Liu C
Ecotoxicology and environmental safety 2024 Mar 1;272:116004
Ecotoxicology and environmental safety 2024 Mar 1;272:116004
Comprehensive Atlas of Alternative Splicing Reveals NSRP1 Promoting Adipogenesis through CCDC18.
Liu L, Wang W, Liu W, Li X, Yi G, Adetula AA, Huang H, Tang Z
International journal of molecular sciences 2024 Mar 1;25(5)
International journal of molecular sciences 2024 Mar 1;25(5)
P2Y(13) receptor involved in HIV-1 gp120 induced neuropathy in superior cervical ganglia through NLRP3 inflammasome activation.
Yin S, Yang X, Li H, Li C, Li C, Chen C, Ye S, Zou L, Liang S, Liu S
Neuropharmacology 2024 Mar 1;245:109818
Neuropharmacology 2024 Mar 1;245:109818
Down-regulating nuclear factor of activated T cells 1 alleviates cognitive deficits in a mouse model of sepsis-associated encephalopathy, possibly by stimulating hippocampal neurogenesis.
Guo Y, Feng Y, Jiang F, Hu L, Shan T, Li H, Liao H, Bao H, Shi H, Si Y
Brain research 2024 Mar 1;1826:148731
Brain research 2024 Mar 1;1826:148731
Decreased NSD2 impairs stromal cell proliferation in human endometrium via reprogramming H3K36me2.
Qin CM, Wei XW, Wu JY, Liu XQ, Lin Y
Reproduction (Cambridge, England) 2024 Mar 1;167(3)
Reproduction (Cambridge, England) 2024 Mar 1;167(3)
Depletion of the N(6)-Methyladenosine (m6A) reader protein IGF2BP3 induces ferroptosis in glioma by modulating the expression of GPX4.
Deng L, Di Y, Chen C, Xia J, Lei B, Li N, Zhang Q
Cell death & disease 2024 Mar 1;15(3):181
Cell death & disease 2024 Mar 1;15(3):181
VD(3)/VDR attenuates bisphenol A-induced impairment in mouse Leydig cells via regulation of autophagy.
Wang L, Zhuang J, Xue Z, Lu H, Zeng W, Zhang T
Journal of food science 2024 Jun;89(6):3858-3870
Journal of food science 2024 Jun;89(6):3858-3870
Knocking Down PIAS3 Reduces H(2)O(2)-induced Oxidative Stress Injury in HT22 Cells.
Wang B, Qian W, Chen K, Li M, Du C
Cell biochemistry and biophysics 2024 Jun;82(2):1381-1387
Cell biochemistry and biophysics 2024 Jun;82(2):1381-1387
Transcriptomic analysis reveals molecular characterization and immune landscape of PANoptosis-related genes in atherosclerosis.
Zheng Z, Li K, Yang Z, Wang X, Shen C, Zhang Y, Lu H, Yin Z, Sha M, Ye J, Zhu L
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Jun;73(6):961-978
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Jun;73(6):961-978
Jiaohong pills attenuate neuroinflammation and amyloid-β protein-induced cognitive deficits by modulating the mitogen-activated protein kinase/nuclear factor kappa-B pathway.
Zhang H, Cai W, Dong L, Yang Q, Li Q, Ran Q, Liu L, Wang Y, Li Y, Weng X, Zhu X, Chen Y
Animal models and experimental medicine 2024 Jun;7(3):222-233
Animal models and experimental medicine 2024 Jun;7(3):222-233
GSK-126 Attenuates Cell Apoptosis in Ischemic Brain Injury by Modulating the EZH2-H3K27me3-Bcl2l1 Axis.
Zhou T, Zhang L, He L, Lan Y, Ding L, Li L, Wang Z
Molecular neurobiology 2024 Jun;61(6):3369-3383
Molecular neurobiology 2024 Jun;61(6):3369-3383
HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression.
Ling H, Li Y, Peng C, Yang S, Seto E
NAR cancer 2024 Jun;6(2):zcae018
NAR cancer 2024 Jun;6(2):zcae018
Nanoparticulate bioceramic putty suppresses osteoclastogenesis and inflammatory bone loss in mice via inhibition of TRAF6-mediated signalling pathways: A laboratory investigation.
Wang Z, Zhang J, Sun X, Yu J, Liu B, Peng B, Wang L, Yang J, Zhu L
International endodontic journal 2024 Jun;57(6):682-699
International endodontic journal 2024 Jun;57(6):682-699
TOPK Inhibition Enhances the Sensitivity of Colorectal Cancer Cells to Radiotherapy by Reducing the DNA Damage Response.
Pang SG, Zhang X, Li ZX, He LF, Chen F, Liu ML, Huang YZ, Mo JM, Luo KL, Xiao JJ, Zhu F
Current medical science 2024 Jun;44(3):545-553
Current medical science 2024 Jun;44(3):545-553
Quercetin, a key active ingredient of Jianpi Zishen Xiehuo Formula, suppresses M1 macrophage polarization and platelet phagocytosis by inhibiting STAT3 activation based on network pharmacology.
Wang W, Xu X, Xu Y, Zhan Y, Wu C, Xiao X, Cheng C, Gao C
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jun;397(6):4219-4233
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jun;397(6):4219-4233
African swine fever virus infection regulates pyroptosis by cleaving gasdermin A via active caspase-3 and caspase-4.
Li S, Song J, Liu J, Zhou S, Zhao G, Li T, Huang L, Li J, Weng C
The Journal of biological chemistry 2024 Jun;300(6):107307
The Journal of biological chemistry 2024 Jun;300(6):107307
Caffeine upregulates SIRT3 expression to ameliorate astrocytes-mediated HIV-1 Tat neurotoxicity via suppression of EGR1 signaling pathway.
Gao L, Sun W, Zhang L, Liang C, Zhang D
Journal of neurovirology 2024 Jun;30(3):286-302
Journal of neurovirology 2024 Jun;30(3):286-302
Insights into the effect of guanylate-binding protein 1 on the survival of Brucella intracellularly.
Li Z, Wang S, Han J, Yang G, Xi L, Zhang C, Cui Y, Yin S, Zhang Y, Zhang H
Veterinary microbiology 2024 Jun;293:110089
Veterinary microbiology 2024 Jun;293:110089
Expression, characterization and antivascular activity of amino acid sequence repeating collagen hexadecapeptide.
Yan W, Huang C, Yan Y, Wang P, Yuwen W, Zhu C, Fu R, Duan Z, Fan D
International journal of biological macromolecules 2024 Jun;270(Pt 1):131886
International journal of biological macromolecules 2024 Jun;270(Pt 1):131886
Saccharomyces boulardii alleviates allergic asthma by restoring gut microbiota and metabolic homeostasis via up-regulation of METTL3 in an m6A-dependent manner.
Liu D, Hu L, Yang Y, Wang Y, Li Y, Su J, Wang G, Gong S
Immunology letters 2024 Jun;267:106853
Immunology letters 2024 Jun;267:106853
Mammalian IRE1α dynamically and functionally coalesces with stress granules.
Liu S, Zhang X, Yao X, Wang G, Huang S, Chen P, Tang M, Cai J, Wu Z, Zhang Y, Xu R, Liu K, He K, Wang Y, Jiang L, Wang QA, Rui L, Liu J, Liu Y
Nature cell biology 2024 Jun;26(6):917-931
Nature cell biology 2024 Jun;26(6):917-931
Landscape of transcriptome-wide m(6)A modification in diabetic liver reveals rewiring of PI3K-Akt signaling after physical exercise.
Chen C, Jiang C, Lin T, Hu Y, Wu H, Xiang Q, Yang M, Wang S, Han X, Tao J
Acta physiologica (Oxford, England) 2024 Jun;240(6):e14154
Acta physiologica (Oxford, England) 2024 Jun;240(6):e14154
Neutrophil extracellular traps formation may be involved in the association of propranolol with the development of portal vein thrombosis.
Xu X, Xu S, Zhang Y, Wang L, Yan C, Xu Z, Zhao Q, Qi X
Thrombosis research 2024 Jun;238:208-221
Thrombosis research 2024 Jun;238:208-221
Isobavachin attenuates osteoclastogenesis and periodontitis-induced bone loss by inhibiting cellular iron accumulation and mitochondrial biogenesis.
Li T, Du Y, Yao H, Zhao B, Wang Z, Chen R, Ji Y, Du M
Biochemical pharmacology 2024 Jun;224:116202
Biochemical pharmacology 2024 Jun;224:116202
Targeting NKAα1 to treat Parkinson's disease through inhibition of mitophagy-dependent ferroptosis.
Zhang X, Li G, Chen H, Nie XW, Bian JS
Free radical biology & medicine 2024 Jun;218:190-204
Free radical biology & medicine 2024 Jun;218:190-204
Senecavirus A induces mitophagy to promote self-replication through direct interaction of 2C protein with K27-linked ubiquitinated TUFM catalyzed by RNF185.
Chen M, Zhang X, Kong F, Gao P, Ge X, Zhou L, Han J, Guo X, Zhang Y, Yang H
Autophagy 2024 Jun;20(6):1286-1313
Autophagy 2024 Jun;20(6):1286-1313
Suppression of N-Glycosylation of Zinc Finger Protein 471 Affects Proliferation, Invasion, and Docetaxel Sensitivity of Tongue Squamous Cell Carcinoma via Regulation of c-Myc.
Liu Y, Cai X, Hu S, Wang Z, Tian H, Wang H
The American journal of pathology 2024 Jun;194(6):1106-1125
The American journal of pathology 2024 Jun;194(6):1106-1125
Obeticholic acid attenuates the intestinal barrier disruption in a rat model of short bowel syndrome.
Hou L, Wang H, Yan M, Cai Y, Zheng R, Ma Y, Tang W, Jiang W
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167221
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167221
Gut microbiota regulates the ALK5/NOX1 axis by altering glutamine metabolism to inhibit ferroptosis of intrahepatic cholangiocarcinoma cells.
Zhang Q, Zhou J, Zhai D, Jiang Q, Yang M, Zhou M
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167152
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167152
OTUD1 enhances gastric cancer aggressiveness by deubiquitinating EBV-encoded protein BALF1 to stabilize the apoptosis inhibitor Bcl-2.
Lin H, Han Y, Sang Y, Wu Y, Tian M, Chen X, Lin X, Lin X
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167132
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167132
Altered landscape of total RNA, tRNA and sncRNA modifications in the liver and spleen of mice infected by Toxoplasma gondii.
Zhang XX, Sun YZ, Wang W, Gao Y, Wei XY, Sun HC, Wang CR, Ni HB, Yang X, Elsheikha HM, Guo HP
PLoS neglected tropical diseases 2024 Jun;18(6):e0012281
PLoS neglected tropical diseases 2024 Jun;18(6):e0012281
The antidepressant effects of protein arginine methyltransferase 2 involve neuroinflammation.
Liu S, Zhang B, Guo H, Ding Z, Hou W, Hu X, Wang Y, Tan W, Zhou S
Neurochemistry international 2024 Jun;176:105728
Neurochemistry international 2024 Jun;176:105728
13-Oxyingenol-dodecanoate inhibits the growth of non-small cell lung cancer cells by targeting ULK1.
Wang XY, Wang YJ, Guo BW, Hou ZL, Zhang GX, Han Z, Liu Q, Yao GD, Song SJ
Bioorganic chemistry 2024 Jun;147:107367
Bioorganic chemistry 2024 Jun;147:107367
Neuroectoderm phenotypes in a human stem cell model of O-GlcNAc transferase associated with intellectual disability.
Murray M, Davidson L, Ferenbach AT, Lefeber D, van Aalten DMF
Molecular genetics and metabolism 2024 Jun;142(2):108492
Molecular genetics and metabolism 2024 Jun;142(2):108492
Neobractatin induces pyroptosis of esophageal cancer cells by TOM20/BAX signaling pathway.
Li Z, Bao Z, Tan J, Chen G, Ye B, Zhao J, Zhang L, Xu H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155547
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155547
Silibinin is a suppressor of the metastasis-promoting transcription factor ID3.
Verdura S, Encinar JA, Gratchev A, Llop-Hernández À, López J, Serrano-Hervás E, Teixidor E, López-Bonet E, Martin-Castillo B, Micol V, Bosch-Barrera J, Cuyàs E, Menendez JA
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155493
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155493
E3 ubiquitin ligase CHIP interacts with transferrin receptor 1 for degradation and promotes cell proliferation through inhibiting ferroptosis in hepatocellular carcinoma.
Shao M, Qi K, Wang L, Yu X, Zhang Q, Yu L, Wang L, Yang C, Fan L
Cellular signalling 2024 Jun;118:111148
Cellular signalling 2024 Jun;118:111148
H3K4me3-Mediated FOXJ2/SLAMF8 Axis Aggravates Thrombosis and Inflammation in β2GPI/Anti-β2GPI-Treated Monocytes.
Tan Y, Qiao J, Yang S, Liu H, Wang Q, Liu Q, Feng W, Cui L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(24):e2309140
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(24):e2309140
Peptide Transporter 1-Mediated Dipeptide Transport Promotes Hepatocellular Carcinoma Metastasis by Activating MAP4K4/G3BP2 Signaling Axis.
Song F, Zhang Z, Liu W, Xu T, Hu X, Wang Q, Zhang W, Ge L, Zhang C, Hu Q, Qin H, Zhang S, Ren X, Fan W, Zhang Y, Huang P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(24):e2306671
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(24):e2306671
Single-Nucleus Multiomic Analyses Identifies Gene Regulatory Dynamics of Phenotypic Modulation in Human Aneurysmal Aortic Root.
Liu X, Zeng Q, Yang H, Li W, Chen Q, Yin K, Pan Z, Wang K, Luo M, Shu C, Zhou Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(22):e2400444
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(22):e2400444
Microglial lipid droplet accumulation in tauopathy brain is regulated by neuronal AMPK.
Li Y, Munoz-Mayorga D, Nie Y, Kang N, Tao Y, Lagerwall J, Pernaci C, Curtin G, Coufal NG, Mertens J, Shi L, Chen X
Cell metabolism 2024 Jun 4;36(6):1351-1370.e8
Cell metabolism 2024 Jun 4;36(6):1351-1370.e8
Proteomics analysis of PK-15 cells infected with porcine parvovirus and the effect of PCBP1 on PPV replication.
Wang L, Song Y, Xu M, Zhang C, Zhang L, Xia L, Wei Z
Microbiology spectrum 2024 Jun 4;12(6):e0391423
Microbiology spectrum 2024 Jun 4;12(6):e0391423
P53 upregulation by USP7-engaging molecular glues.
Li Z, Wang Z, Zhong C, Zhang H, Liu R, An P, Ma Z, Lu J, Pan C, Zhang Z, Cao Z, Hu J, Xing D, Fei Y, Ding Y, Lu B
Science bulletin 2024 Jun 30;69(12):1936-1953
Science bulletin 2024 Jun 30;69(12):1936-1953
Chishao - Fuzi herbal pair restore the macrophage M1/M2 balance in acute-on-chronic liver failure.
Tan N, Jian G, Peng J, Tian X, Chen B
Journal of ethnopharmacology 2024 Jun 28;328:118010
Journal of ethnopharmacology 2024 Jun 28;328:118010
Mammalian orthoreovirus capsid protein σ3 antagonizes RLR-mediated antiviral responses by degrading MAVS.
Li D, Mo R, Li X, Cheng R, Xie J, Li H, Yang Y, Li S, Li H, Yan Z, Wei S, Idris A, Li X, Feng R
mSphere 2024 Jun 25;9(6):e0023624
mSphere 2024 Jun 25;9(6):e0023624
VHL suppresses UBE3B-mediated breast tumor growth and metastasis.
Wang S, Li H, Liu X, Yin T, Li T, Zheng M, Liu M, Meng X, Zhou J, Wang Y, Chen Y
Cell death & disease 2024 Jun 24;15(6):446
Cell death & disease 2024 Jun 24;15(6):446
ZEB2 alleviates Hirschsprung's-associated enterocolitis by promoting the proliferation and differentiation of enteric neural precursor cells via the Notch-1/Jagged-2 pathway.
Feng Y, Zhou C, Zhao F, Ma T, Xiao Y, Peng K, Xia R
Gene 2024 Jun 20;912:148365
Gene 2024 Jun 20;912:148365
Chemotherapy-induced high expression of IL23A enhances efficacy of anti-PD-1 therapy in TNBC by co-activating the PI3K-AKT signaling pathway of CTLs.
Pan F, Liu J, Chen Y, Zhu B, Chen W, Yang Y, Zhu C, Zhao H, Liu X, Xu Y, Xu X, Huo L, Xie L, Wang R, Gu J, Huang G
Scientific reports 2024 Jun 20;14(1):14248
Scientific reports 2024 Jun 20;14(1):14248
Development of a PCSK9-targeted nanoparticle vaccine to effectively decrease the hypercholesterolemia.
Fang Q, Lu X, Zhu Y, Lv X, Yu F, Ma X, Liu B, Zhang H
Cell reports. Medicine 2024 Jun 18;5(6):101614
Cell reports. Medicine 2024 Jun 18;5(6):101614
Graphene Far-Infrared Irradiation Can Effectively Relieve the Blood Pressure Level of Rat Untr-HT in Primary Hypertension.
Lu G, Guo H, Zhang Y, Zhang M, Zhang T, Hu G, Zhang Q
International journal of molecular sciences 2024 Jun 18;25(12)
International journal of molecular sciences 2024 Jun 18;25(12)
Empirical analysis of lead neurotoxicity mode of action and its application in health risk assessment.
Huang H, Lv Y, Chen Q, Huang X, Qin J, Liu Y, Liao Q, Xing X, Chen L, Liu Q, Li S, Long Z, Wang Q, Chen W, Wei Q, Hou M, Hu Q, Xiao Y
Environmental research 2024 Jun 15;251(Pt 2):118708
Environmental research 2024 Jun 15;251(Pt 2):118708
Microglial SIX2 suppresses lipopolysaccharide (LPS)-induced neuroinflammation by up-regulating FXYD2 expression.
Cao XY, Liu Y, Kan JS, Huang XX, Kambey PA, Zhang CT, Gao J
Brain research bulletin 2024 Jun 15;212:110970
Brain research bulletin 2024 Jun 15;212:110970
Involvement of P2X7R-mediated microglia polarization and neuroinflammation in the response to electroacupuncture on post-stroke memory impairment.
Lin B, Wang M, Chen X, Chai L, Ni J, Huang J
Brain research bulletin 2024 Jun 15;212:110967
Brain research bulletin 2024 Jun 15;212:110967
CK1δ/ε kinases regulate TDP-43 phosphorylation and are therapeutic targets for ALS-related TDP-43 hyperphosphorylation.
Ko VI, Ong K, Cleveland DW, Yu H, Ravits JM
Neurobiology of disease 2024 Jun 15;196:106516
Neurobiology of disease 2024 Jun 15;196:106516
Menaquinone-4 alleviates hypoxic-ischemic brain damage in neonatal rats by reducing mitochondrial dysfunction via Sirt1-PGC-1α-TFAM signaling pathway.
Feng X, Zheng Y, Mao N, Shen M, Chu L, Fang Y, Pang M, Wang Z, Lin Z
International immunopharmacology 2024 Jun 15;134:112257
International immunopharmacology 2024 Jun 15;134:112257
Diosmetin ameliorates psoriasis-associated inflammation and keratinocyte hyperproliferation by modulation of PGC-1α / YAP signaling pathway.
Yang D, Peng M, Fu F, Zhao W, Zhang B
International immunopharmacology 2024 Jun 15;134:112248
International immunopharmacology 2024 Jun 15;134:112248
IRTKS contributes to the malignant progression of cervical cancer cells.
Zhang Y, Yi F, Zhang X, Song J, Cai J, Lai J, Song F
Medical oncology (Northwood, London, England) 2024 Jun 13;41(7):174
Medical oncology (Northwood, London, England) 2024 Jun 13;41(7):174
Procyanidin B1 and Coumaric Acid from Highland Barley Alleviated High-Fat-Diet-Induced Hyperlipidemia by Regulating PPARα-Mediated Hepatic Lipid Metabolism and Gut Microbiota in Diabetic C57BL/6J Mice.
Liu Z, Liu J, Tang R, Zhang Z, Tian S
Foods (Basel, Switzerland) 2024 Jun 12;13(12)
Foods (Basel, Switzerland) 2024 Jun 12;13(12)
FBXO43 promotes cell cycle progression in cancer cells through stabilizing SKP2.
Zheng L, Shen J, Chen Y, Lin J, Li P, Zhao X, Ren H, Sun Y, Wang Z
Cancer letters 2024 Jun 1;591:216848
Cancer letters 2024 Jun 1;591:216848
GADD45B in the ventral hippocampal CA1 modulates aversive memory acquisition and spatial cognition.
Huang M, Tao X, Bao J, Wang J, Gong X, Luo L, Pan S, Yang R, Gui Y, Zhou H, Xia Y, Yang Y, Sun B, Liu W, Shu X
Life sciences 2024 Jun 1;346:122618
Life sciences 2024 Jun 1;346:122618
Polystyrene microplastics induce pulmonary fibrosis by promoting alveolar epithelial cell ferroptosis through cGAS/STING signaling.
Zhang J, Du J, Liu D, Zhuo J, Chu L, Li Y, Gao L, Xu M, Chen W, Huang W, Xie L, Chen J, Meng X, Zou F, Cai S, Dong H
Ecotoxicology and environmental safety 2024 Jun 1;277:116357
Ecotoxicology and environmental safety 2024 Jun 1;277:116357
HO-1 upregulation promotes mitophagy-dependent ferroptosis in PM2.5-exposed hippocampal neurons.
Li X, Ran Q, He X, Peng D, Xiong A, Jiang M, Zhang L, Wang J, Bai L, Liu S, Li S, Sun B, Li G
Ecotoxicology and environmental safety 2024 Jun 1;277:116314
Ecotoxicology and environmental safety 2024 Jun 1;277:116314
Amelioration of NAFLD by sleeve gastrectomy-triggered hepatocyte regeneration in mice - experimental research.
Yu T, Ma X, Cheng Y, Wang Z, Zhang G, Ding H, Yin J, Wang Y, Hu S
International journal of surgery (London, England) 2024 Jun 1;110(6):3307-3325
International journal of surgery (London, England) 2024 Jun 1;110(6):3307-3325
Exosomal LncRNA TM7SF3-AU1 Aggravates White Matter Injury via MiR-702-3p/SARM1 Signaling After Subarachnoid Hemorrhage in Rats.
Zhang Z, Yan J, Chen H, Zhao G, Liu L, He J, Xia X, Zhou C, Sun X
Molecular neurobiology 2024 Jul;61(7):4783-4803
Molecular neurobiology 2024 Jul;61(7):4783-4803
Rack1-mediated ferroptosis affects hindgut development in rats with anorectal malformations: Spatial transcriptome insights.
Wang CY, Li MY, Li SY, Wei XG, Dong NX, Liu ST, Yuan ZW, Li B, Pierro A, Tang XB, Bai YZ
Cell proliferation 2024 Jul;57(7):e13618
Cell proliferation 2024 Jul;57(7):e13618
Role of formyl peptide receptor 2 in steatosis of L02 cells exposed to Mono-(2-ethylhexyl) phthalate.
Feng X, Zhang R, Miao X, Li X, Cui J, Xu H, Fang X, Zhou C, Ye L, Zhou L
Environmental toxicology 2024 Jul;39(7):3967-3979
Environmental toxicology 2024 Jul;39(7):3967-3979
The cooperative regulatory effect of the miRNA-130 family on milk fat metabolism in dairy cows.
Li X, Wu Y, Yang X, Gao R, Lu Q, Lv X, Chen Z
Animal bioscience 2024 Jul;37(7):1289-1302
Animal bioscience 2024 Jul;37(7):1289-1302
An arabinogalactan isolated from Cynanchum atratum promotes lymphangiogenesis and lymphatic vessel remodeling to alleviate secondary lymphedema.
Li N, Ruan M, Chen W, Han Y, Yang K, Xu H, Shi S, Wang S, Wang H, Wang Y, Liang Q
International journal of biological macromolecules 2024 Jul;273(Pt 2):133061
International journal of biological macromolecules 2024 Jul;273(Pt 2):133061
A dual role of ERGIC-localized Rabs in TMED10-mediated unconventional protein secretion.
Sun Y, Tao X, Han Y, Lin X, Tian R, Wang H, Chang P, Sun Q, Ge L, Zhang M
Nature cell biology 2024 Jul;26(7):1077-1092
Nature cell biology 2024 Jul;26(7):1077-1092
MICAL-L2, as an estrogen-responsive gene, is involved in ER-positive breast cancer cell progression and tamoxifen sensitivity via the AKT/mTOR pathway.
Wen P, Li J, Wen Z, Guo X, Ma G, Hu S, Xu J, Zhao H, Li R, Liu Y, Wang Y, Gao J
Biochemical pharmacology 2024 Jul;225:116256
Biochemical pharmacology 2024 Jul;225:116256
Selective microRNA expression of exosomes from retinal pigment epithelial cells by oxidative stress.
Zhang Z, Gu Q, Chen L, Yuan D, Gu X, Qian H, Xie P, Liu Q, Hu Z
Vision research 2024 Jul;220:108388
Vision research 2024 Jul;220:108388
Rocaglamide regulates iron homeostasis by suppressing hepcidin expression.
Zhu X, Zuo Q, Xie X, Chen Z, Wang L, Chang L, Liu Y, Luo J, Fang C, Che L, Zhou X, Yao C, Gong C, Hu D, Zhao W, Zhou Y, Zhu S
Free radical biology & medicine 2024 Jul;219:153-162
Free radical biology & medicine 2024 Jul;219:153-162
Cryptochrome 2 Suppresses Epithelial-Mesenchymal Transition by Promoting Trophoblastic Ferroptosis in Unexplained Recurrent Spontaneous Abortion.
Li F, Guo L, Zhou M, Han L, Wu S, Wu L, Yang J
The American journal of pathology 2024 Jul;194(7):1197-1217
The American journal of pathology 2024 Jul;194(7):1197-1217
Direct vagus nerve stimulation: A new tool to control allergic airway inflammation through α7 nicotinic acetylcholine receptor.
Sévoz-Couche C, Liao W, Foo HYC, Bonne I, Lu TB, Tan Qi Hui C, Azhar SH, Peh WYX, Yen SC, Wong WSF
British journal of pharmacology 2024 Jul;181(13):1916-1934
British journal of pharmacology 2024 Jul;181(13):1916-1934
Insect cells of Spodoptera frugiperda support WSSV gene replication but not progeny virion assembly.
Jing SS, Liu LK, Liu HP
Developmental and comparative immunology 2024 Jul;156:105160
Developmental and comparative immunology 2024 Jul;156:105160
GBP2 inhibits pathological angiogenesis in the retina via the AKT/mTOR/VEGFA axis.
Xu X, Ding X, Wang Z, Ye S, Xu J, Liang Z, Luo R, Xu J, Li X, Ren Z
Microvascular research 2024 Jul;154:104689
Microvascular research 2024 Jul;154:104689
Electroacupuncture improves articular microcirculation and attenuates cartilage hypoxia in a male rabbit model of knee osteoarthritis.
Weiwei M, Mei D, Juan L, Longfei X, Xilin C, Tingyao H, Wenting Z, Changqing G
Journal of traditional and complementary medicine 2024 Jul;14(4):414-423
Journal of traditional and complementary medicine 2024 Jul;14(4):414-423
Bushen Huoxue recipe ameliorates ovarian function via promoting BMSCs proliferation and homing to ovaries in POI mice.
Huang Y, Hu R, Liu Z, Geng Y, Li F, Song Y, Ma W, Dong H, Xu L, Zhang M, Song K
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155630
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155630
Shenfu injection targets the PI3K-AKT pathway to regulate autophagy and apoptosis in acute respiratory distress syndrome caused by sepsis.
Chen J, Ding W, Zhang Z, Li Q, Wang M, Feng J, Zhang W, Cao L, Ji X, Nie S, Sun Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155627
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155627
Salvia miltiorrhiza Bge. processed with porcine cardiac blood inhibited GLRX5-mediated ferroptosis alleviating cerebral ischemia-reperfusion injury.
Zhou S, Wang Z, Wang T, Peng C, Zhang J, Liu C, Xu J, Zhang Y, Zhang L, Luo L, Yan X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155622
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155622
Bergenin alleviates proliferative arterial diseases by modulating glucose metabolism in vascular smooth muscle cells.
Song Y, Deng M, Qiu Y, Cui Y, Zhang B, Xin J, Feng L, Mu X, Cui J, Li H, Sun Y, Yi W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155592
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155592
Exploring the anti-skin inflammation substances and mechanism of Paeonia lactiflora Pall. Flower via network pharmacology-HPLC integration.
Chen Y, Li H, Zhang XL, Wang W, Rashed MMA, Duan H, Li LL, Zhai KF
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155565
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155565
Genome sequence and cell biological toolbox of the highly regenerative, coenocytic green feather alga Bryopsis.
Ochiai KK, Hanawa D, Ogawa HA, Tanaka H, Uesaka K, Edzuka T, Shirae-Kurabayashi M, Toyoda A, Itoh T, Goshima G
The Plant journal : for cell and molecular biology 2024 Jul;119(2):1091-1111
The Plant journal : for cell and molecular biology 2024 Jul;119(2):1091-1111
Active secretion of IL-33 from astrocytes is dependent on TMED10 and promotes central nervous system homeostasis.
Jiao M, Wang C, Tang X, Dai C, Zhang N, Fan A, Qian Z, Liu S, Zhang F, Li B, Xu Y, Tan Z, Gong F, Lu Y, Zheng F
Brain, behavior, and immunity 2024 Jul;119:539-553
Brain, behavior, and immunity 2024 Jul;119:539-553
CXXC5 drove inflammation and ovarian cancer proliferation via transcriptional activation of ZNF143 and EGR1.
Geng T, Sun Q, He J, Chen Y, Cheng W, Shen J, Liu B, Zhang M, Wang S, Asan K, Song M, Gao Q, Song Y, Liu R, Liu X, Ding Y, Jing A, Ye X, Ren H, Zeng K, Zhou Y, Zhang B, Ma S, Liu W, Liu S, Ji J
Cellular signalling 2024 Jul;119:111180
Cellular signalling 2024 Jul;119:111180
Transient stimulation of TRPMLs enhance the functionality of hDPCs and facilitate hair growth in mice.
Sun J, Zhang H, Xie B, Shen Y, Zhu Y, Xu W, Zhang B, Song X
Cellular signalling 2024 Jul;119:111167
Cellular signalling 2024 Jul;119:111167
Adiponectin inhibits ROS/NLRP3 inflammatory pathway through FOXO3A to ameliorate oral submucosal fibrosis.
Zeng Y, Luo M, Yao Z, Xiao X
Odontology 2024 Jul;112(3):811-825
Odontology 2024 Jul;112(3):811-825
Luteolin alleviates cadmium-induced metabolism disorder through antioxidant and anti-inflammatory mechanisms in chicken kidney.
Wang X, Zhang K, Ali W, Li J, Huang Q, Liu D, Liu G, Ran D, Liu Z
Poultry science 2024 Jul;103(7):103817
Poultry science 2024 Jul;103(7):103817
Oridonin promotes RSL3-induced ferroptosis in breast cancer cells by regulating the oxidative stress signaling pathway JNK/Nrf2/HO-1.
Ye S, Hu X, Sun S, Su B, Cai J, Jiang J
European journal of pharmacology 2024 Jul 5;974:176620
European journal of pharmacology 2024 Jul 5;974:176620
Genipin improves obesity through promoting bile secretion and changing bile acids composition in diet-induced obese rats.
Guan L, Zhang L, Gong D, Li P, Zhu S, Tang J, Du M, Zhang M, Zou Y
The Journal of pharmacy and pharmacology 2024 Jul 5;76(7):897-907
The Journal of pharmacy and pharmacology 2024 Jul 5;76(7):897-907
ATPR induces acute promyelocytic leukemia cells differentiation and cycle arrest via the lncRNA CONCR/DDX11/PML-RARα signaling axis.
Liu S, Zhan W, He X, Hao M, Shen W, Zhang X, Wang M, Li Z, Hou R, Ou Z, Feng Y, Chen F
Gene 2024 Jul 30;917:148443
Gene 2024 Jul 30;917:148443
Stigmasterol Activates the mTOR Signaling Pathway by Inhibiting ORP5 Ubiquitination to Promote Milk Synthesis in Bovine Mammary Epithelial Cells.
Sun M, Cao Y, Cheng J, Xu D, Li F, Wang J, Ge Y, Liu Y, Long X, Guo W, Liu J, Fu S
Journal of agricultural and food chemistry 2024 Jul 3;72(26):14769-14785
Journal of agricultural and food chemistry 2024 Jul 3;72(26):14769-14785
Narirutin mitigates dextrose sodium sulfate-induced colitis in mice by modulating intestinal flora.
Xu D, Liu D, Jiang N, Xie Y, He D, Cheng J, Liu J, Fu S, Hu G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155730
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155730
Podophyllotoxin via SIRT1/PPAR /NF-κB axis induced cardiac injury in rats based on the toxicological evidence chain (TEC) concept.
Jiang T, Sun L, Wang Y, Zhang F, Guo J, Sun L, Jiang Y, Xue J, Duan J, Liu C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155655
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155655
Overexpression of transcription factor TBX5 inhibits the activation of YAP1-TEAD1 pathway to promote ferroptosis in lung cancer cells.
Ma R, Hu K, Dai S, Wang Y
Biochemical and biophysical research communications 2024 Jul 23;718:150037
Biochemical and biophysical research communications 2024 Jul 23;718:150037
Calorie Restriction Attenuates Memory Impairment and Reduces Neuroinflammation in Obese Aged Rats.
Jantsch J, da Silva Rodrigues F, Silva Dias V, de Farias Fraga G, Eller S, Giovenardi M, Guedes RP
Molecular neurobiology 2024 Jul 22;
Molecular neurobiology 2024 Jul 22;
Fasudil attenuates oxidative stress-induced partial epithelial-mesenchymal transition of tubular epithelial cells in hyperuricemic nephropathy via activating Nrf2.
Cao Y, Wang Y, Li W, Feng J, Chen Y, Chen R, Hu L, Wei J
European journal of pharmacology 2024 Jul 15;975:176640
European journal of pharmacology 2024 Jul 15;975:176640
Identification of activating transcription factor 6 (ATF6) as a novel prognostic biomarker and potential target in oral squamous cell carcinoma.
Wu Y, Xie Q, Wu L, Li Z, Li X, Zhang L, Zhang B
Gene 2024 Jul 15;915:148436
Gene 2024 Jul 15;915:148436
Comprehensive bioinformatics analysis and cell line experiments revealed the important role of CDCA3 in sarcoma.
Li Y, Wu Z, Ding T, Zhang W, Guo H, Huang F
Heliyon 2024 Jul 15;10(13):e32785
Heliyon 2024 Jul 15;10(13):e32785
Discovery of a Covalent Inhibitor That Overcame Resistance to Venetoclax in AML Cells Overexpressing BFL-1.
Lou J, Zhou Q, Lyu X, Cen X, Liu C, Yan Z, Li Y, Tang H, Liu Q, Ding J, Lu Y, Huang H, Xie H, Zhao Y
Journal of medicinal chemistry 2024 Jul 11;67(13):10795-10830
Journal of medicinal chemistry 2024 Jul 11;67(13):10795-10830
AQP1 Deficiency Drives Phthalate-Induced Epithelial Barrier Disruption through Intestinal Inflammation.
Zhao Y, Hu ZY, Lou M, Jiang FW, Huang YF, Chen MS, Wang JX, Liu S, Shi YS, Zhu HM, Li JL
Journal of agricultural and food chemistry 2024 Jul 10;72(27):15334-15344
Journal of agricultural and food chemistry 2024 Jul 10;72(27):15334-15344
Caveolin-1 scaffolding domain-derived peptide enhances erectile function by regulating oxidative stress, mitochondrial dysfunction, and apoptosis of corpus cavernosum smooth muscle cells in rats with cavernous nerve injury.
Xi Y, Feng Z, Xia T, Hong Y, Wu J, Chen J, Ge Y, Xiao H
Life sciences 2024 Jul 1;348:122694
Life sciences 2024 Jul 1;348:122694
Biphasic regulation of miR-17∼92 transcription during hypoxia: roles of HIF1 and p53 hyperphosphorylation at ser15.
Sun MR, Gonzalez S, Huang JB, Zhou Q, Cherukuri A, Adavadkar R, Yan HL, Sun SH, Zhou G, Raj JU, Chen T
American journal of physiology. Lung cellular and molecular physiology 2024 Jul 1;327(1):L102-L113
American journal of physiology. Lung cellular and molecular physiology 2024 Jul 1;327(1):L102-L113
Trailblazing in adjuvant research: succinate's uncharted territory with neutrophils.
Wang Y, Xiu Z, Qu K, Wang L, Wang H, Yu Y
American journal of physiology. Cell physiology 2024 Jul 1;327(1):C1-C10
American journal of physiology. Cell physiology 2024 Jul 1;327(1):C1-C10
Inhibition of TREM-1 alleviates neuroinflammation by modulating microglial polarization via SYK/p38MAPK signaling pathway after traumatic brain injury.
Zhao T, Zhou Y, Zhang D, Han D, Ma J, Li S, Li T, Hu S, Li Z
Brain research 2024 Jul 1;1834:148907
Brain research 2024 Jul 1;1834:148907
Study on the effect of protein lysine lactylation modification in macrophages on inhibiting periodontitis in rats.
Liu X, Wang J, Lao M, Liu F, Zhu H, Man K, Zhang J
Journal of periodontology 2024 Jan;95(1):50-63
Journal of periodontology 2024 Jan;95(1):50-63
Single-Cell RNA Transcriptome of the Human Endometrium Reveals Epithelial Characterizations Associated with Recurrent Implantation Failure.
Zhang H, Zhang C, Zhang S
Advanced biology 2024 Jan;8(1):e2300110
Advanced biology 2024 Jan;8(1):e2300110
Allicin ameliorates sepsis-induced acute kidney injury through Nrf2/HO-1 signaling pathway.
Li XJ, Liu T, Wang Y
Journal of natural medicines 2024 Jan;78(1):53-67
Journal of natural medicines 2024 Jan;78(1):53-67
Soy isoflavone genistein attenuates the efficacy of immune checkpoint therapy in C57BL/6 mice inoculated with B16F1 melanoma and a high PD-L1 expression level reflects tumor resistance.
Yamamoto M, Tanaka Y, Takeda R, Nakamoto A, Nakamoto M, Yagita H, Sakai T
Journal of clinical biochemistry and nutrition 2024 Jan;74(1):57-62
Journal of clinical biochemistry and nutrition 2024 Jan;74(1):57-62
TAPI-1 Exhibits Anti-tumor Efficacy in Human Esophageal Squamous Cell Carcinoma Cells via Suppression of NF-κB Signaling Pathway.
Gao L, Li L, Zhang D, Qiu J, Qian J, Liu H
Digestive diseases and sciences 2024 Jan;69(1):81-94
Digestive diseases and sciences 2024 Jan;69(1):81-94
Mycobacterium tuberculosis PE_PGRS45 (Rv2615c) Promotes Recombinant Mycobacteria Intracellular Survival via Regulation of Innate Immunity, and Inhibition of Cell Apoptosis.
Xu T, Wang C, Li M, Wei J, He Z, Qian Z, Wang X, Wang H
Journal of microbiology (Seoul, Korea) 2024 Jan;62(1):49-62
Journal of microbiology (Seoul, Korea) 2024 Jan;62(1):49-62
A novel AluYb8 insertion-associated non-coding RNA, lncMUTYH, impairs mitochondrial function and dampens the M2-like polarization of macrophages.
Dong G, Yin X, Liang Y, Chen J, Wang J, Jiang F, Wang C, Guo W, Wang Y
Free radical research 2024 Jan;58(1):27-42
Free radical research 2024 Jan;58(1):27-42
Muscle fibre transition and transcriptional changes of horse skeletal muscles during traditional Mongolian endurance training.
Bou T, Ding W, Ren X, Liu H, Gong W, Jia Z, Zhang X, Dugarjaviin M, Bai D
Equine veterinary journal 2024 Jan;56(1):178-192
Equine veterinary journal 2024 Jan;56(1):178-192
Hsa_circ_0001583 fuels bladder cancer metastasis by promoting staphylococcal nuclease and tudor domain containing 1-mediated MicroRNA decay.
Liu C, Cong Y, Chen L, Lv F, Cheng L, Song Y, Xing Y
Neoplasia (New York, N.Y.) 2024 Jan;47:100963
Neoplasia (New York, N.Y.) 2024 Jan;47:100963
PGAM5 exacerbates acute renal injury by initiating mitochondria-dependent apoptosis by facilitating mitochondrial cytochrome c release.
Li JY, Sun XA, Wang X, Yang NH, Xie HY, Guo HJ, Lu L, Xie X, Zhou L, Liu J, Zhang W, Lu LM
Acta pharmacologica Sinica 2024 Jan;45(1):125-136
Acta pharmacologica Sinica 2024 Jan;45(1):125-136
Pb induces the release of CXCL10 and CCL2 chemokines via mtROS/NF-κB activation in BV-2 cells.
Jiang C, Li X, Xiang C, Ye F
Toxicology letters 2024 Jan;391:62-70
Toxicology letters 2024 Jan;391:62-70
Let-7a-5p abrogates progression of papillary thyroid carcinoma cells by decreasing nuclear receptor subfamily 6 group a member 1-mediated lipogenesis.
Zhao T, Sun J, Lu X, Liu L, Chen L, Zhao W, Zhou B
Journal of biochemical and molecular toxicology 2024 Jan;38(1):e23572
Journal of biochemical and molecular toxicology 2024 Jan;38(1):e23572
Serum amyloid A aggravates endotoxin-induced ocular inflammation through the regulation of retinal microglial activation.
Feng H, Zhou W, Yang Y, Zhang X, Mao R, Zhou Y, Cheng T, Xiao H, Rao Y, He J, Zhao P, Li J, Jiang C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan;38(1):e23389
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan;38(1):e23389
CD30 plays a role in T-dependent immune response and T cell proliferation.
Cui D, Zhang Y, Chen L, Du H, Zheng B, Huang M, Li X, Wei J, Chen Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan;38(1):e23365
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan;38(1):e23365
Taxifolin-mediated Nrf2 activation ameliorates oxidative stress and apoptosis for the treatment of glucocorticoid-induced osteonecrosis of the femoral head.
Jiang H, Lin C, Cai T, Jiang L, Lou C, Lin S, Wang W, Yan Z, Pan X, Xue X
Phytotherapy research : PTR 2024 Jan;38(1):156-173
Phytotherapy research : PTR 2024 Jan;38(1):156-173
PCB126 impairs human sperm functions by affecting post-translational modifications and mitochondrial functions.
Yang Y, Mei G, Yang L, Luo T, Wu R, Peng S, Peng Z, Cui J, Cheng Y
Chemosphere 2024 Jan;346:140532
Chemosphere 2024 Jan;346:140532
Ubiquitin ligase NEDD4 promotes the proliferation of hepatocellular carcinoma cells through targeting PCDH17 protein for ubiquitination and degradation.
Liu Z, Hu Q, Hu B, Cao K, Xu T, Hou T, Cao T, Wang R, Shi H, Zhang B
The Journal of biological chemistry 2024 Jan;300(1):105593
The Journal of biological chemistry 2024 Jan;300(1):105593
SynCAM1 deficiency in the hippocampal parvalbumin interneurons contributes to sevoflurane-induced cognitive impairment in neonatal rats.
Zhao MM, Gu HW, Pan WT, Liu PM, Zhu TT, Shang HJ, Jia M, Yang JJ
CNS neuroscience & therapeutics 2024 Jan;30(1):e14554
CNS neuroscience & therapeutics 2024 Jan;30(1):e14554
TRPC3 signalling contributes to the biogenesis of extracellular vesicles.
Padbury EH, Bálint Š, Carollo E, Carter DRF, Becker EBE
Journal of extracellular biology 2024 Jan;3(1):e132
Journal of extracellular biology 2024 Jan;3(1):e132
Exosome‑delivered miR‑486‑3p inhibits the progression of osteosarcoma via sponging CircKEAP1/MARCH1 axis components.
Yang H, He C, Feng Y, Jin J
Oncology letters 2024 Jan;27(1):24
Oncology letters 2024 Jan;27(1):24
Hematoporphyrin derivative photodynamic therapy induces apoptosis and suppresses the migration of human esophageal squamous cell carcinoma cells by regulating the PI3K/AKT/mTOR signaling pathway.
Wei X, Ni J, Yuan L, Li X
Oncology letters 2024 Jan;27(1):17
Oncology letters 2024 Jan;27(1):17
Astragaloside IV promotes exosome secretion of endothelial progenitor cells to regulate PI3KR2/SPRED1 signaling and inhibit pyroptosis of diabetic endothelial cells.
Xiong W, Zhang X, Zhou J, Chen J, Liu Y, Yan Y, Tan M, Huang H, Si Y, Wei Y
Cytotherapy 2024 Jan;26(1):36-50
Cytotherapy 2024 Jan;26(1):36-50
Gut microbial metabolite facilitates colorectal cancer development via ferroptosis inhibition.
Cui W, Guo M, Liu D, Xiao P, Yang C, Huang H, Liang C, Yang Y, Fu X, Zhang Y, Liu J, Shi S, Cong J, Han Z, Xu Y, Du L, Yin C, Zhang Y, Sun J, Gu W, Chai R, Zhu S, Chu B
Nature cell biology 2024 Jan;26(1):124-137
Nature cell biology 2024 Jan;26(1):124-137
Oxidative stress is involved in immunosuppression and macrophage regulation in glioblastoma.
Liang X, Wang Z, Dai Z, Liu J, Zhang H, Wen J, Zhang N, Zhang J, Luo P, Liu Z, Liu Z, Cheng Q
Clinical immunology (Orlando, Fla.) 2024 Jan;258:109802
Clinical immunology (Orlando, Fla.) 2024 Jan;258:109802
Effects of hazelnut soluble dietary fiber on lipid-lowering and gut microbiota in high-fat-diet-fed rats.
Lin H, Li J, Sun M, Wang X, Zhao J, Zhang W, Lv G, Wang Y, Lin Z
International journal of biological macromolecules 2024 Jan;256(Pt 2):128538
International journal of biological macromolecules 2024 Jan;256(Pt 2):128538
Grass carp superoxide dismutases exert antioxidant function and inhibit autophagy to promote grass carp reovirus (GCRV) replication.
Liang X, Wang Q, Wang H, Wang X, Chu P, Yang C, Li Y, Liao L, Zhu Z, Wang Y, He L
International journal of biological macromolecules 2024 Jan;256(Pt 2):128454
International journal of biological macromolecules 2024 Jan;256(Pt 2):128454
Vasculogenic mimicry-associated novel gene signature predicted prognosis and response to immunotherapy in lung adenocarcinoma.
Zhang L, Wu J, Yin WW, Hu J, Liao L, Ma J, Xu Z, Wu S
Pathology, research and practice 2024 Jan;253:155048
Pathology, research and practice 2024 Jan;253:155048
TESC acts as a prognostic factor and promotes epithelial-mesenchymal transition progression in esophageal squamous carcinoma.
Dong Y, Fan B, Li M, Zhang J, Xie S, Di S, Jia Q, Gong T
Pathology, research and practice 2024 Jan;253:154964
Pathology, research and practice 2024 Jan;253:154964
NAMPT regulates mitochondria function and lipid metabolism during porcine oocyte maturation.
Guo X, Jiao L, Yi Y, Zhang HL, Liu YX, Wang ZY, Sun SC
Journal of cellular physiology 2024 Jan;239(1):180-192
Journal of cellular physiology 2024 Jan;239(1):180-192
Hydrogen sulfide attenuates depression-like behaviours in Parkinson's disease model rats by improving synaptic plasticity in a hippocampal Warburg effect-dependent manner.
Liu F, Tian Q, Tang HL, Cheng X, Zou W, Zhang P
Pharmacology, biochemistry, and behavior 2024 Jan;234:173677
Pharmacology, biochemistry, and behavior 2024 Jan;234:173677
Malonate differentially affects cell survival and confers chemoresistance in cancer cells via the induction of p53-dependent autophagy.
Cui H, Zhu B, Li H, Meng Y, Cai M, Wang H, Yuan M, Zhong X, Wang B, Shan H, Zhe Miao M, Chai K, Zheng J, Zhang L, Liu Y
Biochemical pharmacology 2024 Jan;219:115950
Biochemical pharmacology 2024 Jan;219:115950
Clemastine-induced enhancement of hippocampal myelination alleviates memory impairment in mice with chronic pain.
Zhu TT, Wang H, Liu PM, Gu HW, Pan WT, Zhao MM, Hashimoto K, Yang JJ
Neurobiology of disease 2024 Jan;190:106375
Neurobiology of disease 2024 Jan;190:106375
Hepatocyte growth factor attenuates high glucose-disturbed mitochondrial dynamics in podocytes by decreasing ARF6-dependent DRP1 translocation.
Li Y, Li X, Yang Y, Li F, Chen Q, Zhao Z, Zhang N, Li H
Biochimica et biophysica acta. Molecular cell research 2024 Jan;1871(1):119623
Biochimica et biophysica acta. Molecular cell research 2024 Jan;1871(1):119623
Myo6 mediates osteoclast function and is essential for joint damage in collagen-induced arthritis.
Tan H, Ma L, Qin T, Liu K, Liu Y, Wen C, You K, Pang C, Luo H, Wei L, Shu Y, Yang X, Shen X, Zhou C
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166902
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166902
CARD9 deficiency aggravated nonalcoholic steatohepatitis in mice through increasing inflammatory response.
Liu X, Fang Y, Qian C, Chen J, Luo W, Zuo W, Lin J, Xie L, Liang G, Huang L, Wang Y
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166893
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166893
Melatonin inhibits fibroblast cell functions and hypertrophic scar formation by enhancing autophagy through the MT2 receptor-inhibited PI3K/Akt /mTOR signaling.
Dong Y, Cao X, Huang J, Hu Z, Chen C, Chen M, Long Q, Xu Z, Lv D, Rong Y, Luo S, Wang H, Deng W, Tang B
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166887
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166887
Eupatilin inhibits xanthine oxidase in vitro and attenuates hyperuricemia and renal injury in vivo.
Xu G, Wu L, Yang H, Liu T, Tong Y, Wan J, Han B, Zhou L, Hu X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Jan;183:114307
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Jan;183:114307
6-Gingerol regulates triglyceride and cholesterol biosynthesis to improve hepatic steatosis in MAFLD by activating the AMPK-SREBPs signaling pathway.
Xia Q, Lu F, Chen Y, Li J, Huang Z, Fang K, Hu M, Guo Y, Dong H, Xu L, Gong J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:116060
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:116060
Berberine exerts antidepressant effects in vivo and in vitro through the PI3K/AKT/CREB/BDNF signaling pathway.
Tang Y, Su H, Nie K, Wang H, Gao Y, Chen S, Lu F, Dong H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:116012
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:116012
Exercise ameliorating myocardial injury in type 2 diabetic rats by inhibiting excessive mitochondrial fission involving increased irisin expression and AMP-activated protein kinase phosphorylation.
Wang B, Zhao C, Wang Y, Tian X, Lin J, Zhu B, Zhou Y, Zhang X, Li N, Sun Y, Xu H, Zhao R
Journal of diabetes 2024 Jan;16(1):e13475
Journal of diabetes 2024 Jan;16(1):e13475
Brassisterol A, a new ergosterol from co-cultivation of fungi attenuates neuroinflammation via targeting NLRP3/caspase-1/GSDMD pathway.
Tong Z, Kong L, Zhang Y, Hu T, Dai R, Wang Y, Ji J, Huang Z, Hu L
Bioorganic chemistry 2024 Jan;142:106955
Bioorganic chemistry 2024 Jan;142:106955
ARID5B-mediated LINC01128 epigenetically activated pyroptosis and apoptosis by promoting the formation of the BTF3/STAT3 complex in β2GPI/anti-β2GPI-treated monocytes.
Tan Y, Qiao J, Yang S, Wang Q, Liu H, Liu Q, Feng W, Yang B, Li Z, Cui L
Clinical and translational medicine 2024 Jan;14(1):e1539
Clinical and translational medicine 2024 Jan;14(1):e1539
The homologous tumor-derived-exosomes loaded with miR-1270 selectively enhanced the suppression effect for colorectal cancer cells.
Jin Y, Sun L, Chen Y, Lu Y
Cancer medicine 2024 Jan;13(1):e6936
Cancer medicine 2024 Jan;13(1):e6936
Taxifolin inhibits melanoma proliferation/migration impeding USP18/Rac1/JNK/β-catenin oncogenic signaling.
Xu L, Zhang L, Zhang S, Yang J, Zhu A, Sun J, Kalvakolanu DV, Cong X, Zhang J, Tang J, Guo B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155199
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155199
Radix Astragali decoction improves liver regeneration by upregulating hepatic expression of aquaporin-9.
Li Y, Yang X, Bao T, Sun X, Li X, Zhu H, Zhang B, Ma T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155166
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155166
Targeting HSP70 chaperones by rhein sensitizes liver cancer to artemisinin derivatives.
Wang J, Zhang J, Guo Z, Hua H, Zhang H, Liu Y, Jiang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155156
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155156
Hyperoxia-induced airflow restriction and Renin-Angiotensin System expression in a bronchopulmonary dysplasia mouse model.
Dowell J, Bice Z, Yan K, Konduri GG
Physiological reports 2024 Jan;12(1):e15895
Physiological reports 2024 Jan;12(1):e15895
Branched-Chain Amino Acid Accumulation Fuels the Senescence-Associated Secretory Phenotype.
Liang Y, Pan C, Yin T, Wang L, Gao X, Wang E, Quang H, Huang D, Tan L, Xiang K, Wang Y, Alexander PB, Li QJ, Yao TP, Zhang Z, Wang XF
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(2):e2303489
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(2):e2303489
let-7g sensitized liver cancer cells to 5-fluorouracil by downregulating ABCC10 expression.
Chen Y, Zhang B, Zhong C, Zhou Y, Xue L, Luo C, Yi L, Gong Q, Long Y
Chemical biology & drug design 2024 Jan;103(1):e14396
Chemical biology & drug design 2024 Jan;103(1):e14396
Drp1 regulated PINK1-dependent mitophagy protected duck follicular granulosa cells from acute heat stress injury.
Yang C, Luo P, Yang YT, Fu XL, Li BX, Shen X, Xu DN, Huang YM, Tian YB, Liu WJ
Poultry science 2024 Jan;103(1):103247
Poultry science 2024 Jan;103(1):103247
Resveratrol alleviates heat-stress-induced impairment of the jejunal mucosa through TLR4/MAPK signaling pathway in black-boned chicken.
Liu L, Gong X, Zhang X, Zhang D, Tang Y, Liu J, Li Y, Pan D
Poultry science 2024 Jan;103(1):103242
Poultry science 2024 Jan;103(1):103242
Gut microbiota regulates host melatonin production through epithelial cell MyD88.
Liu B, Fan L, Wang Y, Wang H, Yan Y, Chen S, Hung I, Liu C, Wei H, Ge L, Ren W
Gut microbes 2024 Jan-Dec;16(1):2313769
Gut microbes 2024 Jan-Dec;16(1):2313769
SH3RF2 contributes to cisplatin resistance in ovarian cancer cells by promoting RBPMS degradation.
Gong TT, Liu FH, Xiao Q, Li YZ, Wei YF, Xu HL, Cao F, Sun ML, Jiang FL, Tao T, Ma QP, Qin X, Song Y, Gao S, Wu L, Zhao YH, Huang DH, Wu QJ
Communications biology 2024 Jan 9;7(1):67
Communications biology 2024 Jan 9;7(1):67
The E3 ligase NEURL3 suppresses epithelial-mesenchymal transition and metastasis in nasopharyngeal carcinoma by promoting vimentin degradation.
Zhou SQ, Feng P, Ye ML, Huang SY, He SW, Zhu XH, Chen J, Zhang Q, Li YQ
Journal of experimental & clinical cancer research : CR 2024 Jan 9;43(1):14
Journal of experimental & clinical cancer research : CR 2024 Jan 9;43(1):14
Novel lissencephaly-associated NDEL1 variant reveals distinct roles of NDE1 and NDEL1 in nucleokinesis and human cortical malformations.
Tsai MH, Ke HC, Lin WC, Nian FS, Huang CW, Cheng HY, Hsu CS, Granata T, Chang CH, Castellotti B, Lin SY, Doniselli FM, Lu CJ, Franceschetti S, Ragona F, Hou PS, Canafoglia L, Tung CY, Lee MH, Wang WJ, Tsai JW
Acta neuropathologica 2024 Jan 9;147(1):13
Acta neuropathologica 2024 Jan 9;147(1):13
Near-infrared-responsive GE11-CuS@Gal nanoparticles as an intelligent drug release system for targeting therapy against oral squamous cell carcinoma.
Lan Q, Wang S, Chen Z, Hua J, Hu J, Luo S, Xu Y
International journal of pharmaceutics 2024 Jan 5;649:123667
International journal of pharmaceutics 2024 Jan 5;649:123667
Engineered exosomes mediated targeted delivery of neuroprotective peptide NR2B9c for the treatment of traumatic brain injury.
Haroon K, Zheng H, Wu S, Liu Z, Tang Y, Yang GY, Liu Y, Zhang Z
International journal of pharmaceutics 2024 Jan 5;649:123656
International journal of pharmaceutics 2024 Jan 5;649:123656
Gestational exposure to 1-NP induces ferroptosis in placental trophoblasts via CYP1B1/ERK signaling pathway leading to fetal growth restriction.
Yu S, Mu Y, Wang K, Wang L, Wang C, Yang Z, Liu Y, Li S, Zhang M
Chemico-biological interactions 2024 Jan 5;387:110812
Chemico-biological interactions 2024 Jan 5;387:110812
Diosgenin alters LPS-induced macrophage polarization by activating PPARγ/NF-κB signaling pathway.
Xiang X, Xin X, Hou Y, Deng Y, Liu X, Yu W
International immunopharmacology 2024 Jan 5;126:111270
International immunopharmacology 2024 Jan 5;126:111270
Knockdown of Smox protects the integrity of the blood-brain barrier through antioxidant effect and Nrf2 pathway activation in stroke.
Wang G, Li Z, Lin P, Zhang H, Wang Y, Zhang T, Wang H, Li H, Lin L, Zhao Y, Jia L, Chen Y, Ji H, Zhao W, Fu Z, Zhong Z
International immunopharmacology 2024 Jan 5;126:111183
International immunopharmacology 2024 Jan 5;126:111183
A framework for Frizzled-G protein coupling and implications to the PCP signaling pathways.
Zhang Z, Lin X, Wei L, Wu Y, Xu L, Wu L, Wei X, Zhao S, Zhu X, Xu F
Cell discovery 2024 Jan 5;10(1):3
Cell discovery 2024 Jan 5;10(1):3
TIMELESS promotes reprogramming of glucose metabolism in oral squamous cell carcinoma.
Chen Y, Han Z, Zhang L, Gao C, Wei J, Yang X, Han Y, Li Y, Zhang C, Wei Y, Dong J, Xun W, Sun W, Zhang T, Zhang H, Chen J, Yuan P
Journal of translational medicine 2024 Jan 4;22(1):21
Journal of translational medicine 2024 Jan 4;22(1):21
TET2-mediated tumor cGAS triggers endothelial STING activation to regulate vasculature remodeling and anti-tumor immunity in liver cancer.
Lv H, Zong Q, Chen C, Lv G, Xiang W, Xing F, Jiang G, Yan B, Sun X, Ma Y, Wang L, Wu Z, Cui X, Wang H, Yang W
Nature communications 2024 Jan 4;15(1):6
Nature communications 2024 Jan 4;15(1):6
Adipose-derived stem cell exosomes promote tumor characterization and immunosuppressive microenvironment in breast cancer.
Zhu Q, Cao Y, Yuan J, Hu Y
Cancer immunology, immunotherapy : CII 2024 Jan 31;73(2):39
Cancer immunology, immunotherapy : CII 2024 Jan 31;73(2):39
Methionine Promotes Milk Synthesis through the BRCC36-BRG1-mTOR Signaling Axis in Mammary Epithelial Cells.
Xie L, Li R, Zhang J, Li H, Gao X, Zhang M
Journal of agricultural and food chemistry 2024 Jan 31;72(4):2135-2144
Journal of agricultural and food chemistry 2024 Jan 31;72(4):2135-2144
A network pharmacology approach and experimental validation to investigate the anticancer mechanism of Qi-Qin-Hu-Chang formula against colitis-associated colorectal cancer through induction of apoptosis via JNK/p38 MAPK signaling pathway.
Wu Y, Fang Y, Li Y, Au R, Cheng C, Li W, Xu F, Cui Y, Zhu L, Shen H
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117323
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117323
Huaier suppresses cisplatin resistance in non-small cell lung cancer by inhibiting the JNK/JUN/IL-8 signaling pathway.
Jin H, Liu C, Liu X, Wang H, Zhang Y, Liu Y, Li J, Yu Z, Liu HX
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117270
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117270
Prunella vulgaris L. attenuates gut dysbiosis and endotoxin leakage against alcoholic liver disease.
Rao PL, Shen YH, Song YJ, Xu Y, Xu HX
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117237
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117237
The protective effect of apolipoprotein H in paediatric sepsis.
Yu Z, Xiao C, Liu R, Pi D, Jin B, Zou Z, Xu F
Critical care (London, England) 2024 Jan 30;28(1):36
Critical care (London, England) 2024 Jan 30;28(1):36
A peptide from the Japanese encephalitis virus failed to induce the production of anti-N-methyl-d-aspartate receptor antibodies via molecular mimicry in mice.
Luo H, Yang J, Yang X, Han Z, Fang Z, Huang D, Gui J, Ding R, Chen H, Cheng L, Ma J, Jiang L
Heliyon 2024 Jan 30;10(2):e24700
Heliyon 2024 Jan 30;10(2):e24700
Huc-MSC-derived exosomal miR-144 alleviates inflammation in LPS-induced preeclampsia-like pregnant rats via the FosB/Flt-1 pathway.
Sun J, Zhang W
Heliyon 2024 Jan 30;10(2):e24575
Heliyon 2024 Jan 30;10(2):e24575
TET2-mediated ECM1 hypomethylation promotes the neovascularization in active proliferative diabetic retinopathy.
Cai C, Gu C, He S, Meng C, Lai D, Zhang J, Qiu Q
Clinical epigenetics 2024 Jan 3;16(1):6
Clinical epigenetics 2024 Jan 3;16(1):6
Porcine Intestinal Mucosal Peptides Target Macrophage-Modulated Inflammation and Alleviate Intestinal Homeostasis in Dextrose Sodium Sulfate-Induced Colitis in Mice.
Wang Y, Xie Z, Wu X, Du L, Chong Z, Liu R, Han J
Foods (Basel, Switzerland) 2024 Jan 3;13(1)
Foods (Basel, Switzerland) 2024 Jan 3;13(1)
Antioxidative Sirt1 and the Keap1-Nrf2 Signaling Pathway Impair Inflammation and Positively Regulate Autophagy in Murine Mammary Epithelial Cells or Mammary Glands Infected with Streptococcus uberis.
Khan S, Wang T, Cobo ER, Liang B, Khan MA, Xu M, Qu W, Gao J, Barkema HW, Kastelic JP, Liu G, Han B
Antioxidants (Basel, Switzerland) 2024 Jan 29;13(2)
Antioxidants (Basel, Switzerland) 2024 Jan 29;13(2)
Deciphering the tumor-suppressive role of PSMB9 in melanoma through multi-omics and single-cell transcriptome analyses.
Hu X, Hu Z, Zhang H, Zhang N, Feng H, Jia X, Zhang C, Cheng Q
Cancer letters 2024 Jan 28;581:216466
Cancer letters 2024 Jan 28;581:216466
Phosphorylated α-synuclein deposited in Schwann cells interacting with TLR2 mediates cell damage and induces Parkinson's disease autonomic dysfunction.
Li Y, Tong Q, Wang Y, Cheng Y, Geng Y, Tian T, Yuan Y, Fan Y, Lu M, Zhang K
Cell death discovery 2024 Jan 26;10(1):52
Cell death discovery 2024 Jan 26;10(1):52
Endoplasmic reticulum aminopeptidase 2 regulates CD4(+) T cells pyroptosis in rheumatoid arthritis.
Zhang J, Cai H, Sun W, Wu W, Nan Y, Ni Y, Wu X, Chen M, Xu H, Wang Y
Arthritis research & therapy 2024 Jan 25;26(1):36
Arthritis research & therapy 2024 Jan 25;26(1):36
SHMT2 promotes papillary thyroid cancer metastasis through epigenetic activation of AKT signaling.
Sun M, Zhao M, Li R, Zhang Y, Shi X, Ding C, Ma C, Lu J, Yue X
Cell death & disease 2024 Jan 25;15(1):87
Cell death & disease 2024 Jan 25;15(1):87
Morroniside-mediated mitigation of stem cell and endothelial cell dysfunction for the therapy of glucocorticoid-induced osteonecrosis of the femoral head.
Jiang H, Wang W, Mao Y, Jiang L, Yu J, Zhu X, Fu H, Lin Z, Shen H, Pan X, Xue X
International immunopharmacology 2024 Jan 25;127:111421
International immunopharmacology 2024 Jan 25;127:111421
Gypenoside XLIX attenuates sepsis-induced splenic injury through inhibiting inflammation and oxidative stress.
Xu B, Yang R, Qiang J, Xu X, Zhou M, Ji X, Lu Y, Dong Z
International immunopharmacology 2024 Jan 25;127:111420
International immunopharmacology 2024 Jan 25;127:111420
TDP43/HDAC6/Prdx1 signaling pathway participated in the cognitive impairment of obstructive sleep apnea via regulating inflammation and oxidative stress.
Ou Y, Shen C, Chen Z, Liu T, Peng Y, Zong D, Ouyang R
International immunopharmacology 2024 Jan 25;127:111350
International immunopharmacology 2024 Jan 25;127:111350
Panax notoginseng saponin R1 improves glucocorticoid-inhibited airway epithelium repair via glucocorticoid receptor β.
Yang L, Xu M, Zhang L, Zhang M, Wu W, Luo Z, Tian D, Fu Z, Zou W
International immunopharmacology 2024 Jan 25;127:111347
International immunopharmacology 2024 Jan 25;127:111347
Cold-inducible RNA-binding protein induces inflammatory responses via NF-κB signaling pathway in normal human bronchial epithelial cells infected with streptococcus pneumoniae.
Zhang R, Fang K, Mu C, Zhang L
International immunopharmacology 2024 Jan 25;127:111338
International immunopharmacology 2024 Jan 25;127:111338
METTL1 mediated tRNA m(7)G modification promotes leukaemogenesis of AML via tRNA regulated translational control.
Zhao P, Xia L, Chen D, Xu W, Guo H, Xu Y, Yan B, Wu X, Li Y, Zhang Y, Zhang X
Experimental hematology & oncology 2024 Jan 24;13(1):8
Experimental hematology & oncology 2024 Jan 24;13(1):8
Integrin β1-rich extracellular vesicles of kidney recruit Fn1+ macrophages to aggravate ischemia-reperfusion-induced inflammation.
Wang W, Ren X, Chen X, Hong Q, Cai G
JCI insight 2024 Jan 23;9(2)
JCI insight 2024 Jan 23;9(2)
Exogenous carbon monoxide promotes GPX4-dependent ferroptosis through ROS/GSK3β axis in non-small cell lung cancer.
Cao W, Sun M, Yu KN, Zhao L, Feng Y, Tan C, Yang M, Wang Y, Zhu F, Chen L, Nie L, Zhao Y, Chen G, Han W
Cell death discovery 2024 Jan 23;10(1):42
Cell death discovery 2024 Jan 23;10(1):42
LDLR is used as a cell entry receptor by multiple alphaviruses.
Zhai X, Li X, Veit M, Wang N, Wang Y, Merits A, Jiang Z, Qin Y, Zhang X, Qi K, Jiao H, He WT, Chen Y, Mao Y, Su S
Nature communications 2024 Jan 20;15(1):622
Nature communications 2024 Jan 20;15(1):622
Targeting gut microbial nitrogen recycling and cellular uptake of ammonium to improve bortezomib resistance in multiple myeloma.
Zhu Y, Jian X, Chen S, An G, Jiang D, Yang Q, Zhang J, Hu J, Qiu Y, Feng X, Guo J, Chen X, Li Z, Zhou R, Hu C, He N, Shi F, Huang S, Liu H, Li X, Xie L, Zhu Y, Zhao L, Jiang Y, Li J, Wang J, Qiu L, Chen X, Jia W, He Y, Zhou W
Cell metabolism 2024 Jan 2;36(1):159-175.e8
Cell metabolism 2024 Jan 2;36(1):159-175.e8
Pharmaceutical targeting of OTUB2 sensitizes tumors to cytotoxic T cells via degradation of PD-L1.
Ren W, Xu Z, Chang Y, Ju F, Wu H, Liang Z, Zhao M, Wang N, Lin Y, Xu C, Chen S, Rao Y, Lin C, Yang J, Liu P, Zhang J, Huang C, Xia N
Nature communications 2024 Jan 2;15(1):9
Nature communications 2024 Jan 2;15(1):9
FOXP3(+) regulatory T cell perturbation mediated by the IFNγ-STAT1-IFITM3 feedback loop is essential for anti-tumor immunity.
Liu X, Zhang W, Han Y, Cheng H, Liu Q, Ke S, Zhu F, Lu Y, Dai X, Wang C, Huang G, Su B, Zou Q, Li H, Zhao W, Xiao L, Lu L, Tong X, Pan F, Li H, Li B
Nature communications 2024 Jan 2;15(1):122
Nature communications 2024 Jan 2;15(1):122
YTHDF3 modulates the Cbln1 level by recruiting BTG2 and is implicated in the impaired cognition of prenatal hypoxia offspring.
Lu L, Shi Y, Wei B, Li W, Yu X, Zhao Y, Yu D, Sun M
iScience 2024 Jan 19;27(1):108703
iScience 2024 Jan 19;27(1):108703
Hexamethylene amiloride synergizes with venetoclax to induce lysosome-dependent cell death in acute myeloid leukemia.
Jiang X, Huang K, Sun X, Li Y, Hua L, Liu F, Huang R, Du J, Zeng H
iScience 2024 Jan 19;27(1):108691
iScience 2024 Jan 19;27(1):108691
Phosphorylation-dependent membraneless organelle fusion and fission illustrated by postsynaptic density assemblies.
Wu H, Chen X, Shen Z, Li H, Liang S, Lu Y, Zhang M
Molecular cell 2024 Jan 18;84(2):309-326.e7
Molecular cell 2024 Jan 18;84(2):309-326.e7
Loss of LBP triggers lipid metabolic disorder through H3K27 acetylation-mediated C/EBPβ- SCD activation in non-alcoholic fatty liver disease.
Zhu YL, Meng LL, Ma JH, Yuan X, Chen SW, Yi XR, Li XY, Wang Y, Tang YS, Xue M, Zhu MZ, Peng J, Lu XJ, Huang JZ, Song ZC, Wu C, Zheng KZ, Dai QQ, Huang F, Fang HS
Zoological research 2024 Jan 18;45(1):79-94
Zoological research 2024 Jan 18;45(1):79-94
MTFR2-dependent mitochondrial fission promotes HCC progression.
Zhang L, Zhang X, Liu H, Yang C, Yu J, Zhao W, Guo J, Zhou B, Jiang N
Journal of translational medicine 2024 Jan 18;22(1):73
Journal of translational medicine 2024 Jan 18;22(1):73
The SIRT1/Nrf2 signaling pathway mediates the anti-pulmonary fibrosis effect of liquiritigenin.
Hua Q, Ren L
Chinese medicine 2024 Jan 18;19(1):12
Chinese medicine 2024 Jan 18;19(1):12
Metabolic regulation of homologous recombination repair by MRE11 lactylation.
Chen Y, Wu J, Zhai L, Zhang T, Yin H, Gao H, Zhao F, Wang Z, Yang X, Jin M, Huang B, Ding X, Li R, Yang J, He Y, Wang Q, Wang W, Kloeber JA, Li Y, Hao B, Zhang Y, Wang J, Tan M, Li K, Wang P, Lou Z, Yuan J
Cell 2024 Jan 18;187(2):294-311.e21
Cell 2024 Jan 18;187(2):294-311.e21
Transcription factor Sp1 transcriptionally enhances GSDME expression for pyroptosis.
Pan J, Li Y, Gao W, Jiang Q, Geng L, Ding J, Li S, Li J
Cell death & disease 2024 Jan 18;15(1):66
Cell death & disease 2024 Jan 18;15(1):66
USP29 activation mediated by FUBP1 promotes AURKB stability and oncogenic functions in gastric cancer.
Tu R, Kang Y, Pan Y, Da Y, Ren D, Zhang R, Cai Z, Liu Y, Xu J, Ma J, Zhou Z, Yin S, Li X, Zhang P, Zhang Q, Wang J, Lu X, Zhang C
Cancer cell international 2024 Jan 17;24(1):33
Cancer cell international 2024 Jan 17;24(1):33
Egr-1 is a key regulator of the blood-brain barrier damage induced by meningitic Escherichia coli.
Yang R, Wang X, Liu H, Chen J, Tan C, Chen H, Wang X
Cell communication and signaling : CCS 2024 Jan 17;22(1):44
Cell communication and signaling : CCS 2024 Jan 17;22(1):44
Antitumor Effect of Platinum-Modified STING Agonist MSA-2.
Wang M, Cai Y, He T, Zhang Y, Yi L, Li W, Zhou P
ACS omega 2024 Jan 16;9(2):2650-2656
ACS omega 2024 Jan 16;9(2):2650-2656
MicroRNA-218-5p-Ddx41 axis restrains microglia-mediated neuroinflammation through downregulating type I interferon response in a mouse model of Parkinson's disease.
Wang D, Gao H, Qin Q, Li J, Zhao J, Qu Y, Li J, Xiong Y, Min Z, Mao Z, Xue Z
Journal of translational medicine 2024 Jan 16;22(1):63
Journal of translational medicine 2024 Jan 16;22(1):63
Cell surface GRP78: A potential therapeutic target for high glucose-induced endothelial injury.
Wang B, He X, Zhang J, Zhang Y
Biochemical and biophysical research communications 2024 Jan 15;692:149347
Biochemical and biophysical research communications 2024 Jan 15;692:149347
Resveratrol protected against the development of endometriosis by promoting ferroptosis through miR-21-3p/p53/SLC7A11 signaling pathway.
Zou W, Wang X, Xia X, Zhang T, Nie M, Xiong J, Fang X
Biochemical and biophysical research communications 2024 Jan 15;692:149338
Biochemical and biophysical research communications 2024 Jan 15;692:149338
Celastrol-loaded bovine serum albumin nanoparticles target inflamed neutrophils for improved rheumatoid arthritis therapy.
Liu S, Liu M, Xiu J, Zhang T, Zhang B, Cun D, Yang C, Li K, Zhang J, Zhao X
Acta biomaterialia 2024 Jan 15;174:345-357
Acta biomaterialia 2024 Jan 15;174:345-357
Multi-monoubiquitylation controls VASP-mediated actin dynamics.
McCormick LE, Suarez C, Herring LE, Cannon KS, Kovar DR, Brown NG, Gupton SL
Journal of cell science 2024 Jan 15;137(2)
Journal of cell science 2024 Jan 15;137(2)
MicroRNA-146a-loaded magnesium silicate nanospheres promote bone regeneration in an inflammatory microenvironment.
Yang J, Shuai J, Siow L, Lu J, Sun M, An W, Yu M, Wang B, Chen Q
Bone research 2024 Jan 15;12(1):2
Bone research 2024 Jan 15;12(1):2
Identification and Validation of a Prognostic Signature Derived from the Cancer Stem Cells for Oral Squamous Cell Carcinoma.
Shi M, Huang K, Wei J, Wang S, Yang W, Wang H, Li Y
International journal of molecular sciences 2024 Jan 14;25(2)
International journal of molecular sciences 2024 Jan 14;25(2)
From Hit to Lead: Structure-Based Optimization of Novel Selective Inhibitors of Receptor-Interacting Protein Kinase 1 (RIPK1) for the Treatment of Inflammatory Diseases.
Zhang L, Li Y, Tian C, Yang R, Wang Y, Xu H, Zhu Q, Chen S, Li L, Yang S
Journal of medicinal chemistry 2024 Jan 11;67(1):754-773
Journal of medicinal chemistry 2024 Jan 11;67(1):754-773
PHB2 promotes SHIP2 ubiquitination via the E3 ligase NEDD4 to regulate AKT signaling in gastric cancer.
Xu L, Xiang W, Yang J, Gao J, Wang X, Meng L, Ye K, Zhao XH, Zhang XD, Jin L, Ye Y
Journal of experimental & clinical cancer research : CR 2024 Jan 11;43(1):17
Journal of experimental & clinical cancer research : CR 2024 Jan 11;43(1):17
Gentiopicroside inhibits the progression of gastric cancer through modulating EGFR/PI3K/AKT signaling pathway.
Chen Q, Zhang T, Li B, Zhu Z, Ma X, Zhang Y, Li L, Zhu J, Zhang G
European journal of medical research 2024 Jan 11;29(1):47
European journal of medical research 2024 Jan 11;29(1):47
Orange-spotted grouper nervous necrosis virus-encoded protein A induces interferon expression via RIG-I/MDA5-MAVS-TBK1-IRF3 signaling in fish cells.
Huang S, Huang Y, Su T, Huang R, Su L, Wu Y, Weng S, He J, Xie J
Microbiology spectrum 2024 Jan 11;12(1):e0453222
Microbiology spectrum 2024 Jan 11;12(1):e0453222
Podophyllotoxin-mediated neurotoxicity via the microbiota-gut-brain axis in SD rats based on the toxicological evidence chain (TEC) concept.
Duan J, Sun J, Jiang T, Ma X, Li X, Wang Y, Zhang F, Liu C
The Science of the total environment 2024 Jan 10;907:168106
The Science of the total environment 2024 Jan 10;907:168106
Acylated Ghrelin Activates PI3K/mTOR Signaling Pathway by Promoting ThPOK Acetylation to Promote Milk Fat Synthesis in Bovine Mammary Epithelial Cells.
Wang J, Cao Y, Long X, Li F, Jiang N, Sun M, Xie Y, Ge Y, Guo W, Liu J, Fu S
Journal of agricultural and food chemistry 2024 Jan 10;72(1):390-404
Journal of agricultural and food chemistry 2024 Jan 10;72(1):390-404
Chinese herbal medicine alleviates autophagy and apoptosis in ovarian granulosa cells induced by testosterone through PI3K/AKT1/FOXO1 pathway.
Hu W, Xie N, Pan M, Zhang Q, Zhang H, Wang F, Qu F
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117025
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117025
Xiaobanxia decoction alleviates chemotherapy-induced nausea and vomiting by inhibiting GSDME-mediated pyroptosis.
Liao X, Ye B, Hu W, Han J, Zhao Y, Dai Y, Wu X, Mo Z, Wei L, Nie K
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):116970
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):116970
Inhibitory effect of Lonicera japonica-derived exosomal miR2911 on human papilloma virus.
Chi Y, Shi L, Lu S, Cui H, Zha W, Shan L, Shen Y
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):116969
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):116969
Xiao-Ban-Xia decoction mitigates cisplatin-induced emesis via restoring PINK1/Parkin mediated mitophagy deficiency in a rat pica model.
Zhao Y, Han J, Hu W, Dai Y, Wu X, Liao X, Zhou H, Nie K
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116882
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116882
ETV7 promotes colorectal cancer progression through upregulation of IFIT3.
Chai B, Li Y, Guo Y, Zhang Z, Jia K, Chai X, Suo Y
Functional & integrative genomics 2024 Jan 10;24(1):8
Functional & integrative genomics 2024 Jan 10;24(1):8
ALCAT1-mediated abnormal cardiolipin remodelling promotes mitochondrial injury in podocytes in diabetic kidney disease.
Hao Y, Fan Y, Feng J, Zhu Z, Luo Z, Hu H, Li W, Yang H, Ding G
Cell communication and signaling : CCS 2024 Jan 10;22(1):26
Cell communication and signaling : CCS 2024 Jan 10;22(1):26
PFKFB3 promotes endometriosis cell proliferation via enhancing the protein stability of β-catenin.
Ling X, Liu L, Jiang A, Shi X, Liu L, Wang X, Lu C, Ren C, Yu Z
Molecular and cellular endocrinology 2024 Jan 1;579:112083
Molecular and cellular endocrinology 2024 Jan 1;579:112083
Blocking the interaction between circTNRC18 and LIN28A promotes trophoblast epithelial-mesenchymal transformation and alleviates preeclampsia.
Chen LL, Li YQ, Kang ZH, Zhang X, Gu SY, Wang N, Shen XY
Molecular and cellular endocrinology 2024 Jan 1;579:112073
Molecular and cellular endocrinology 2024 Jan 1;579:112073
Aging-related NOX4-Nrf2 redox imbalance increases susceptibility to cisplatin-induced acute kidney injury by regulating mitophagy.
Hu J, Hou W, Ma N, Zhang Y, Liu X, Wang Y, Ci X
Life sciences 2024 Jan 1;336:122352
Life sciences 2024 Jan 1;336:122352
Parkin-mediated mitophagy is a potential treatment for oxaliplatin-induced peripheral neuropathy.
Zhao G, Zhang T, Li J, Li L, Chen P, Zhang C, Li K, Cui C
American journal of physiology. Cell physiology 2024 Jan 1;326(1):C214-C228
American journal of physiology. Cell physiology 2024 Jan 1;326(1):C214-C228
Low beauvericin concentrations promote PC-12 cell survival under oxidative stress by regulating lipid metabolism and PI3K/AKT/mTOR signaling.
Hu L, Sui X, Dong X, Li Z, Lun S, Wang S
Ecotoxicology and environmental safety 2024 Jan 1;269:115786
Ecotoxicology and environmental safety 2024 Jan 1;269:115786
Synergistic anticancer effect by targeting CDK2 and EGFR-ERK signaling.
Wu J, Chen Y, Li R, Guan Y, Chen M, Yin H, Yang X, Jin M, Huang B, Ding X, Yang J, Wang Z, He Y, Wang Q, Luo J, Wang P, Mao Z, Huen MSY, Lou Z, Yuan J, Gong F
The Journal of cell biology 2024 Jan 1;223(1)
The Journal of cell biology 2024 Jan 1;223(1)
Proteolysis Targeting Chimeras (PROTACs) based on celastrol induce multiple protein degradation for triple-negative breast cancer treatment.
Gan X, Wang F, Luo J, Zhao Y, Wang Y, Yu C, Chen J
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2024 Jan 1;192:106624
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2024 Jan 1;192:106624
Rapid turnover of CTLA4 is associated with a complex architecture of reversible ubiquitylation.
Tey PY, Dufner A, Knobeloch KP, Pruneda JN, Clague MJ, Urbé S
bioRxiv : the preprint server for biology 2024 Jan 1;
bioRxiv : the preprint server for biology 2024 Jan 1;
The E3 ubiquitin ligase TRIM9 regulates synaptic function and actin dynamics.
McCormick LE, Evans EB, Barker NK, Herring LE, Diering GH, Gupton SL
bioRxiv : the preprint server for biology 2024 Jan 1;
bioRxiv : the preprint server for biology 2024 Jan 1;
Demethylase FTO-Mediated m6A Modification of lncRNA MEG3 Activates Neuronal Pyroptosis via NLRP3 Signaling in Cerebral Ischemic Stroke.
Yan H, Huang W, Rao J, Yan D, Yuan J
Molecular neurobiology 2024 Feb;61(2):1023-1043
Molecular neurobiology 2024 Feb;61(2):1023-1043
LncRNA JHDM1D-AS1 promotes osteogenic differentiation of periodontal ligament cells by targeting miR-532-5p to activate IGF1R signaling.
Zhong X, Wang H
Journal of periodontal research 2024 Feb;59(1):220-230
Journal of periodontal research 2024 Feb;59(1):220-230
Omega-3 polyunsaturated fatty acids and its metabolite 12-HEPE rescue busulfan disrupted spermatogenesis via target to GPR120.
Jing J, Ouyang L, Zhang H, Liang K, Ma R, Ge X, Tang T, Zhao S, Xue T, Shen J, Ma J, Li Z, Wu J, Yang Y, Zhao W, Zheng L, Qian Z, Sun S, Ge Y, Chen L, Li C, Yao B
Cell proliferation 2024 Feb;57(2):e13551
Cell proliferation 2024 Feb;57(2):e13551
Pyruvate kinase M2 regulates kidney fibrosis through pericyte glycolysis during the progression from acute kidney injury to chronic kidney disease.
Chen Y, Bai X, Chen J, Huang M, Hong Q, Ouyang Q, Sun X, Zhang Y, Liu J, Wang X, Wu L, Chen X
Cell proliferation 2024 Feb;57(2):e13548
Cell proliferation 2024 Feb;57(2):e13548
Helicobacter pylori CagA-mediated ether lipid biosynthesis promotes ferroptosis susceptibility in gastric cancer.
Peng Y, Lei X, Yang Q, Zhang G, He S, Wang M, Ling R, Zheng B, He J, Chen X, Li F, Zhou Q, Zhao L, Ye G, Li G
Experimental & molecular medicine 2024 Feb;56(2):441-452
Experimental & molecular medicine 2024 Feb;56(2):441-452
A Study on the Acquisition and Identification of Beige Adipocytes and Exosomes as Well as Their Inflammatory Regulation by Promoting Macrophage Polarization.
Wu B, Cen W, Liu C, Wang T, Wei J, Wang S, Zhang D, Li C
Aesthetic plastic surgery 2024 Feb;48(3):519-529
Aesthetic plastic surgery 2024 Feb;48(3):519-529
Overexpressed FAM111B degrades GSDMA to promote esophageal cancer tumorigenesis and cisplatin resistance.
Wang H, Wang H, Chen J, Liu P, Xiao X
Cellular oncology (Dordrecht, Netherlands) 2024 Feb;47(1):343-359
Cellular oncology (Dordrecht, Netherlands) 2024 Feb;47(1):343-359
NQO1 Mediates Lenvatinib Resistance by Regulating ROS-induced Apoptosis in Hepatocellular Carcinoma.
Xue W, Wang T, Tian WJ, Pang SQ, Zhang HF, Jia WD
Current medical science 2024 Feb;44(1):168-179
Current medical science 2024 Feb;44(1):168-179
Synergistic effect of adavosertib and fimepinostat on acute myeloid leukemia cells by enhancing the induction of DNA damage.
Wang Y, Lin X, Wang Y, Wang G
Investigational new drugs 2024 Feb;42(1):70-79
Investigational new drugs 2024 Feb;42(1):70-79
The protein kinase A signaling pathway mediates the effect of electroacupuncture on excessive contraction of the bladder detrusor in a rat model of neurogenic bladder.
Liu Q, Qu QR, Xu M, Liu JS, Qi F, Yi XQ, Zhang H, Zhou L, Ai K
Acupuncture in medicine : journal of the British Medical Acupuncture Society 2024 Feb;42(1):32-38
Acupuncture in medicine : journal of the British Medical Acupuncture Society 2024 Feb;42(1):32-38
Hsp90 β is critical for the infection of severe fever with thrombocytopenia syndrome virus.
Wang B, Zhang L, Deng F, Hu Z, Wang M, Liu J
Virologica Sinica 2024 Feb;39(1):113-122
Virologica Sinica 2024 Feb;39(1):113-122
The role and mechanism of RIPK1 in vascular endothelial dysfunction in chronic kidney disease.
Wang C, Chen H, Su H, Sheng Q, Lang Y, Yu Q, Lv Z, Wang R
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Feb;38(2):e23446
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Feb;38(2):e23446
Oral administration of punicalagin attenuates imiquimod-induced psoriasis by reducing ROS generation and inflammation via MAPK/ERK and NF-κB signaling pathways.
Wang Y, Han D, Huang Y, Dai Y, Wang Y, Liu M, Wang N, Yin T, Du W, He K, Zheng Y
Phytotherapy research : PTR 2024 Feb;38(2):713-726
Phytotherapy research : PTR 2024 Feb;38(2):713-726
[Adipose-derived stem cell-derived exosomes regulate Th2/Treg balance in peripheral blood of AR patients through the mTOR pathway].
Han F, Xu X, Wang Y
Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery 2024 Feb;38(2):140-145
Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery 2024 Feb;38(2):140-145
Serabelisib regulates GSDMD-mediated pyroptosis, apoptosis and migration of hepatoma cells via the PI3K/Akt/E-cadherin signaling pathway.
Li M, Huang Z, Zhou Y
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2024 Feb;33(2):171-181
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2024 Feb;33(2):171-181
Tasquinimod enhances the sensitivity of ovarian cancer cells to cisplatin by regulating the Nur77-Bcl-2 apoptotic pathway.
Lin Y, Liu YQ, Zhu KA, Hu MQ, Li Z, Min XJ
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2024 Feb;33(2):151-161
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2024 Feb;33(2):151-161
Targeted transplantation of engineered mitochondrial compound promotes functional recovery after spinal cord injury by enhancing macrophage phagocytosis.
Xu J, Shi C, Yuan F, Ding Y, Xie Y, Liu Y, Zhu F, Lu H, Duan C, Hu J, Jiang L
Bioactive materials 2024 Feb;32:427-444
Bioactive materials 2024 Feb;32:427-444
Comprehensive analysis of PSMD family members and validation of PSMD9 as a potential therapeutic target in human glioblastoma.
Li Y, Liu X, Zhao F, Zhao Z, Li X, Wang J, Huang B, Chen A
CNS neuroscience & therapeutics 2024 Feb;30(2):e14366
CNS neuroscience & therapeutics 2024 Feb;30(2):e14366
CIA-II is associated with lower-grade glioma survival and cell proliferation.
Xiao F, Zhu H, Guo Y, Zhang Z, Sun G, Xiao Y, Hu G, Huang K, Guo H
CNS neuroscience & therapeutics 2024 Feb;30(2):e14340
CNS neuroscience & therapeutics 2024 Feb;30(2):e14340
Tanshinone IIA, a component of the self-made Xiao-Yin decoction, ameliorates psoriasis by inhibiting IL-17/IL-23 and PTGS2/NF-κB/AP-1 pathways.
Fu L, Li M, Wang P, Chen L, Huang J, Zhang H
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2024 Feb;30(2):e13577
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2024 Feb;30(2):e13577
miR‑186‑5p regulates the inflammatory response of chronic obstructive pulmonary disorder by targeting HIF‑1α.
Fu Y, Zhao J, Chen J, Zheng Y, Mo R, Zhang L, Zhang B, Lin Q, He C, Li S, Lin L, Xie T, Ding Y
Molecular medicine reports 2024 Feb;29(2)
Molecular medicine reports 2024 Feb;29(2)
Identification of differentially expressed genes associated with ferroptosis in Crohn's disease.
Zhang W, Li Z, Li H, Zhang D
Experimental and therapeutic medicine 2024 Feb;27(2):89
Experimental and therapeutic medicine 2024 Feb;27(2):89
JAM2 is a prognostic biomarker and inhibits proliferation, metastasis and epithelial-mesenchymal transition in lung adenocarcinoma.
Dong Y, Zhang J, Xie S, Di S, Fan B, Gong T
The journal of gene medicine 2024 Feb;26(2):e3679
The journal of gene medicine 2024 Feb;26(2):e3679
A dihydromyricetin-loaded phellinus igniarius polysaccharide/l-arginine modified chitosan-based hydrogel for promoting wound recovery in diabetic mice via JNK and TGF-β/Smad signaling pathway.
Yang J, Zhang L, Sun S, Zhang S, Ding Q, Chai G, Yu W, Zhao T, Shen L, Gao Y, Liu W, Ding C
International journal of biological macromolecules 2024 Feb;259(Pt 1):129124
International journal of biological macromolecules 2024 Feb;259(Pt 1):129124
Natural isoflavone glabridin targets PI3Kγ as an adjuvant to increase the sensitivity of MDA-MB-231 to tamoxifen and DU145 to paclitaxel.
Lin H, Ai D, Liu Q, Wang X, Chen Q, Hong Z, Tao Y, Gao J, Wang L
The Journal of steroid biochemistry and molecular biology 2024 Feb;236:106426
The Journal of steroid biochemistry and molecular biology 2024 Feb;236:106426
Repression of YEATS2 induces cellular senescence in hepatocellular carcinoma and inhibits tumor growth.
Wu Q, Zheng Q, Yuan L, Gao D, Hu Y, Jiang X, Zhai Q, Liu M, Xu L, Xu H, Ye J, Zhang F
Cell cycle (Georgetown, Tex.) 2024 Feb;23(4):478-494
Cell cycle (Georgetown, Tex.) 2024 Feb;23(4):478-494
Upregulation of TRIM16 mitigates doxorubicin-induced cardiotoxicity by modulating TAK1 and YAP/Nrf2 pathways in mice.
Guo X, Liu M, Han B, Zheng Y, Zhang K, Bao G, Gao C, Shi H, Sun Q, Zhao Z
Biochemical pharmacology 2024 Feb;220:116009
Biochemical pharmacology 2024 Feb;220:116009
PCSK9 regulates myofibroblast transformation through the JAK2/STAT3 pathway to regulate fibrosis after myocardial infarction.
Bao H, Wang X, Zhou H, Zhou W, Liao F, Wei F, Yang S, Luo Z, Li W
Biochemical pharmacology 2024 Feb;220:115996
Biochemical pharmacology 2024 Feb;220:115996
Gestational exposure to bisphenol AF causes endocrine disorder of corpus luteum by altering ovarian SIRT-1/Nrf2/NF-kB expressions and macrophage proangiogenic function in mice.
Lu S, Liu M, Liu H, Yang C, Zhu J, Ling Y, Kuang H
Biochemical pharmacology 2024 Feb;220:115954
Biochemical pharmacology 2024 Feb;220:115954
Fructus Ligustri Lucidi inhibits ferroptosis in ovariectomy‑induced osteoporosis in rats via the Nrf2/HO‑1 signaling pathway.
Li P, Wang Y, Yan Q, Yang Y, Zhu R, Ma J, Chen Y, Liu H, Zhang Z
Biomedical reports 2024 Feb;20(2):27
Biomedical reports 2024 Feb;20(2):27
BAP18 acting as a novel peroxisome proliferator-activated receptor α co-regulator contributes to hepatocellular carcinoma progression.
Liu W, Wang S, Lin L, Zou R, Sun H, Zeng K, Wu Y, Li Y, Shigeaki K, Wang X, Wang C, Zhao Y
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166974
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166974
Palmitic acid and trans-4-hydroxy-3-methoxycinnamate, the active ingredients of Yaobishu formula, reduce inflammation and pain by regulating gut microbiota and metabolic changes after lumbar disc herniation to activate autophagy and the Wnt/β-catenin pathway.
Li S, Chen T, Zhou Y, Li X
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166972
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166972
Farnesoid X receptor overexpression prevents hepatic steatosis through inhibiting AIM2 inflammasome activation in nonalcoholic fatty liver disease.
Xu S, Kong L, Li L, Wang C, Gu J, Luo H, Meng Q
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166930
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166930
Fluorene-9-bisphenol exposure damages the testis in mice through a novel mechanism of ferroptosis.
Feng Q, Liu Y, Zou L, Lei M, Zhu C, Xia W
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Feb;184:114385
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Feb;184:114385
Human umbilical cord-derived mesenchymal stem cells ameliorate liver fibrosis by improving mitochondrial function via Slc25a47-Sirt3 signaling pathway.
Chen P, Yuan M, Yao L, Xiong Z, Liu P, Wang Z, Jiang Y, Li L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Feb;171:116133
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Feb;171:116133
HDAC6-MYCN-CXCL3 axis mediates allergic inflammation and is necessary for allergic inflammation-promoted cellular interactions.
Kwon Y, Choi Y, Kim M, Jo H, Jeong MS, Jung HS, Jeoung D
Molecular immunology 2024 Feb;166:1-15
Molecular immunology 2024 Feb;166:1-15
Extra villous trophoblast-derived PDL1 can ameliorate macrophage inflammation and promote immune adaptation associated with preeclampsia.
Cui Y, Wu S, Liu K, Zhao H, Ma B, Gong L, Zhou Q, Li X
Journal of reproductive immunology 2024 Feb;161:104186
Journal of reproductive immunology 2024 Feb;161:104186
Gestational Diabetes Mellitus Remodels the Fetal Brain Fatty Acid Profile Through Placenta-Brain Lipid Axis in C57BL/6J Mice.
Yu HT, Gong JY, Xu WH, Chen YR, Li YT, Chen YF, Liu GL, Zhang HY, Xie L
The Journal of nutrition 2024 Feb;154(2):590-599
The Journal of nutrition 2024 Feb;154(2):590-599
The involvement of RNA N6-methyladenosine and histone methylation modification in decidualization and endometriosis-associated infertility.
Lin X, Dai Y, Gu W, Zhang Y, Zhuo F, Zhao F, Jin X, Li C, Huang D, Tong X, Zhang S
Clinical and translational medicine 2024 Feb;14(2):e1564
Clinical and translational medicine 2024 Feb;14(2):e1564
KLF4 interacts with TXNIP to modulate the pyroptosis in ulcerative colitis via regulating NLRP3 signaling.
Chen Y, Sun L, Liu H, Li J, Guo L, Wang Z
Immunity, inflammation and disease 2024 Feb;12(2):e1199
Immunity, inflammation and disease 2024 Feb;12(2):e1199
Sustainable inflammatory activation following spinal cord injury is driven by thrombin-mediated dynamic expression of astrocytic chemokines.
He B, Niu L, Li S, Li H, Hou Y, Li A, Zhang X, Hao H, Song H, Cai R, Zhou Y, Wang Y, Wang Y
Brain, behavior, and immunity 2024 Feb;116:85-100
Brain, behavior, and immunity 2024 Feb;116:85-100
Coenzyme Q10 Protects Against Hyperlipidemia-Induced Osteoporosis by Improving Mitochondrial Function via Modulating miR-130b-3p/PGC-1α Pathway.
Meng M, Wang J, Wang C, Zhao J, Wang H, Zhang Y, Sun H, Liu M
Calcified tissue international 2024 Feb;114(2):182-199
Calcified tissue international 2024 Feb;114(2):182-199
A Novel Cargo Delivery System-AnCar-Exo(LaIMTS) Ameliorates Arthritis via Specifically Targeting Pro-Inflammatory Macrophages.
Li S, Wu YR, Peng XQ, Chen HG, Zhang TY, Chen H, Yang J, Xie YL, Qi HB, Xiang W, Huang B, Zhou SR, Hu Y, Tan QY, Du XL, Huang JL, Zhang RB, Li XH, Luo FT, Jin M, Su N, Luo XQ, Huang S, Yang P, Yan XJ, Lian JQ, Zhu Y, Xiong Y, Xiao GY, Liu YY, Shen C, Kuang L, Ni ZH, Chen L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(7):e2306143
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(7):e2306143
METTL16 inhibits papillary thyroid cancer tumorigenicity through m(6)A/YTHDC2/SCD1-regulated lipid metabolism.
Li Q, Wang Y, Meng X, Wang W, Duan F, Chen S, Zhang Y, Sheng Z, Gao Y, Zhou L
Cellular and molecular life sciences : CMLS 2024 Feb 9;81(1):81
Cellular and molecular life sciences : CMLS 2024 Feb 9;81(1):81
Balancing macrophage polarization via stem cell-derived apoptotic bodies for diabetic wound healing.
Mao J, Qian S, Zhao Q, Zhao B, Lu B, Zhang L, Mao X, Zhang Y, Cui W, Sun X
Med (New York, N.Y.) 2024 Feb 9;5(2):148-168.e8
Med (New York, N.Y.) 2024 Feb 9;5(2):148-168.e8
MTHFD1 regulates the NADPH redox homeostasis in MYCN-amplified neuroblastoma.
Guan J, Li M, Wang Y, Zhang Y, Que Y, Lu S, Wang J, Zhu J, Huang J, Zhen Z, Sun F, Song M, Zhang Y
Cell death & disease 2024 Feb 9;15(2):124
Cell death & disease 2024 Feb 9;15(2):124
Collecting duct NCOR1 controls blood pressure by regulating mineralocorticoid receptor.
Sun K, Wang YL, Hou CC, Shang D, Du LJ, Bai L, Zhang XY, Hao CM, Duan SZ
Journal of advanced research 2024 Feb 8;
Journal of advanced research 2024 Feb 8;
Whey Protein Peptide Pro-Glu-Trp Ameliorates Hyperuricemia by Enhancing Intestinal Uric Acid Excretion, Modulating the Gut Microbiota, and Protecting the Intestinal Barrier in Rats.
Qi X, Ma Y, Guan K, Zhao L, Ma Y, Wang R
Journal of agricultural and food chemistry 2024 Feb 7;72(5):2573-2584
Journal of agricultural and food chemistry 2024 Feb 7;72(5):2573-2584
A mouse model to distinguish NLRP6-mediated inflammasome-dependent and -independent functions.
Li R, Zan Y, Wang D, Chen X, Wang A, Tan H, Zhang G, Ding S, Shen C, Wu H, Zhu S
Proceedings of the National Academy of Sciences of the United States of America 2024 Feb 6;121(6):e2321419121
Proceedings of the National Academy of Sciences of the United States of America 2024 Feb 6;121(6):e2321419121
Identification of a potential signature to predict the risk of postmenopausal osteoporosis.
Geng Y, Shao R, Xu T, Zhang L
Gene 2024 Feb 5;894:147942
Gene 2024 Feb 5;894:147942
MicroRNA-148a-3p suppresses the glycolysis and Cell proliferation by targeting transmembrane protein 54 in liver cancer.
Yuan X, Wen Y, Shi Q, Zhao Y, Ding J
Biochemical and biophysical research communications 2024 Feb 5;695:149424
Biochemical and biophysical research communications 2024 Feb 5;695:149424
JMJD3 regulate H3K27me3 modification via interacting directly with TET1 to affect spermatogonia self-renewal and proliferation.
Wang J, Liu L, Li Z, Wang H, Ren Y, Wang K, Liu Y, Tao X, Zheng L
BMC genomics 2024 Feb 29;25(1):225
BMC genomics 2024 Feb 29;25(1):225
Warm Acupuncture Reduces Pain and Inflammation in Rats with Lumbar Disc Herniation Induced by Autologous Nucleus Pulposus Transplantation via Regulating p38MAPK/NF-κB Pathway.
Pan F, Zeng F, Chen Y, Zheng Y, Chen Z, Zhu X, Yin MF, Huang Y, Liu Z
Journal of acupuncture and meridian studies 2024 Feb 29;17(1):28-37
Journal of acupuncture and meridian studies 2024 Feb 29;17(1):28-37
Preliminary exploration of the potential biological functions and prognosis values of RAB4B in pan-cancer combing with experimental validation in BLCA.
Li K, Liang S, Mi H
Translational cancer research 2024 Feb 29;13(2):613-633
Translational cancer research 2024 Feb 29;13(2):613-633
The ARID1A-METTL3-m6A axis ensures effective RNase H1-mediated resolution of R-loops and genome stability.
Zhang J, Chen F, Tang M, Xu W, Tian Y, Liu Z, Shu Y, Yang H, Zhu Q, Lu X, Peng B, Liu X, Xu X, Gullerova M, Zhu WG
Cell reports 2024 Feb 27;43(2):113779
Cell reports 2024 Feb 27;43(2):113779
Human YKT6 forms priming complex with STX17 and SNAP29 to facilitate autophagosome-lysosome fusion.
Zheng D, Tong M, Zhang S, Pan Y, Zhao Y, Zhong Q, Liu X
Cell reports 2024 Feb 27;43(2):113760
Cell reports 2024 Feb 27;43(2):113760
p53 promotes antiviral innate immunity by driving hexosamine metabolism.
Xia W, Jiang P
Cell reports 2024 Feb 27;43(2):113724
Cell reports 2024 Feb 27;43(2):113724
ALOX5 drives the pyroptosis of CD4(+) T cells and tissue inflammation in rheumatoid arthritis.
Cai H, Zhang J, Xu H, Sun W, Wu W, Dong C, Zhou P, Xue C, Nan Y, Ni Y, Wu X, Gu Z, Chen M, Wang Y
Science signaling 2024 Feb 27;17(825):eadh1178
Science signaling 2024 Feb 27;17(825):eadh1178
Nucleoporin Seh1 controls murine neocortical development via transcriptional repression of p21 in neural stem cells.
Dai W, Liu Z, Yan M, Nian X, Hong F, Zhou Z, Wang C, Fu X, Li X, Jiang M, Zhu Y, Huang Q, Lu X, Hou L, Yan N, Wang Q, Hu J, Mo W, Zhang X, Zhang L
Developmental cell 2024 Feb 26;59(4):482-495.e6
Developmental cell 2024 Feb 26;59(4):482-495.e6
EGR1 mediates MDR1 transcriptional activity regulating gemcitabine resistance in pancreatic cancer.
Yang Z, Chen F, Wei D, Chen F, Jiang H, Qin S
BMC cancer 2024 Feb 26;24(1):268
BMC cancer 2024 Feb 26;24(1):268
S-nitrosothiol homeostasis maintained by ADH5 facilitates STING-dependent host defense against pathogens.
Jia M, Chai L, Wang J, Wang M, Qin D, Song H, Fu Y, Zhao C, Gao C, Jia J, Zhao W
Nature communications 2024 Feb 26;15(1):1750
Nature communications 2024 Feb 26;15(1):1750
NINJ1 mediates inflammatory cell death, PANoptosis, and lethality during infection conditions and heat stress.
Han JH, Karki R, Malireddi RKS, Mall R, Sarkar R, Sharma BR, Klein J, Berns H, Pisharath H, Pruett-Miller SM, Bae SJ, Kanneganti TD
Nature communications 2024 Feb 26;15(1):1739
Nature communications 2024 Feb 26;15(1):1739
DIA proteomics analysis reveals the mechanism of folic acid-induced acute kidney injury and the effects of icariin.
Zhang D, Liu S, Jiang H, Liu S, Kong F
Chemico-biological interactions 2024 Feb 25;390:110878
Chemico-biological interactions 2024 Feb 25;390:110878
Ameliorative Effect of Coenzyme Q10 on Phenotypic Transformation in Human Smooth Muscle Cells with FBN1 Knockdown.
Zhang X, Zhang Z, Wan S, Qi J, Hao Y, An P, Luo Y, Luo J
International journal of molecular sciences 2024 Feb 25;25(5)
International journal of molecular sciences 2024 Feb 25;25(5)
Synergistic suppression of ovarian cancer by combining NRF2 and GPX4 inhibitors: in vitro and in vivo evidence.
Li N, Jiang X, Zhang Q, Huang Y, Wei J, Zhang H, Luo H
Journal of ovarian research 2024 Feb 23;17(1):49
Journal of ovarian research 2024 Feb 23;17(1):49
Protective effects of Pt-N-C single-atom nanozymes against myocardial ischemia-reperfusion injury.
Ye T, Chen C, Wang D, Huang C, Yan Z, Chen Y, Jin X, Wang X, Ding X, Shen C
Nature communications 2024 Feb 23;15(1):1682
Nature communications 2024 Feb 23;15(1):1682
Discovery of D25, a Potent and Selective MNK Inhibitor for Sepsis-Associated Acute Spleen Injury.
Li Q, Ke L, Yu D, Xu H, Zhang Z, Yu R, Jiang T, Guo YW, Su M, Jin X
Journal of medicinal chemistry 2024 Feb 22;67(4):3167-3189
Journal of medicinal chemistry 2024 Feb 22;67(4):3167-3189
Development of Potent MALT1 Inhibitors Featuring a Novel "2-Thioxo-2,3-dihydrothiazolo[4,5-d]pyrimidin-7(6H)-one" Scaffold for the Treatment of B Cell Lymphoma.
Liang X, Yu H, Liang R, Feng Z, Saidahmatov A, Sun C, Ren H, Wei X, Zhao J, Yang C, Liu H
Journal of medicinal chemistry 2024 Feb 22;67(4):2884-2906
Journal of medicinal chemistry 2024 Feb 22;67(4):2884-2906
The Parkinson's disease related mutant VPS35 (D620N) amplifies the LRRK2 response to endolysosomal stress.
McCarron KR, Elcocks H, Mortiboys H, Urbé S, Clague MJ
The Biochemical journal 2024 Feb 21;481(4):265-278
The Biochemical journal 2024 Feb 21;481(4):265-278
Nel-like Molecule Type 1 Combined with Gold Nanoparticles Modulates Macrophage Polarization, Osteoclastogenesis, and Oral Microbiota in Periodontitis.
Liao W, Ni C, Ge R, Li Y, Jiang S, Yang W, Yan F
ACS applied materials & interfaces 2024 Feb 21;16(7):8442-8458
ACS applied materials & interfaces 2024 Feb 21;16(7):8442-8458
HMGA1 drives chemoresistance in esophageal squamous cell carcinoma by suppressing ferroptosis.
Yang JY, Lei XY, He KY, Guo JR, Liu MJ, Li JQ, Li QT, Jiang ZH, Zhang L, Wu DH, Li YJ, Sun QH, Jian YP, Xu ZX
Cell death & disease 2024 Feb 21;15(2):158
Cell death & disease 2024 Feb 21;15(2):158
[Protective effect of FAK inhibitor PF-562271 against human umbilical vein endothelial cell injury induced by aging platelets].
Bai Y, Gang B, Zhang M, Wan Z, Liu G, Gu W
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2024 Feb 20;44(2):252-259
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2024 Feb 20;44(2):252-259
The pathogenicity of vancomycin-resistant Enterococcus faecalis to colon cancer cells.
Zhang L, Deng M, Liu J, Zhang J, Wang F, Yu W
BMC infectious diseases 2024 Feb 20;24(1):230
BMC infectious diseases 2024 Feb 20;24(1):230
P21 resists ferroptosis in osteoarthritic chondrocytes by regulating GPX4 protein stability.
Zheng Z, Shang X, Sun K, Hou Y, Zhang X, Xu J, Liu H, Ruan Z, Hou L, Guo Z, Wang G, Xu F, Guo F
Free radical biology & medicine 2024 Feb 20;212:336-348
Free radical biology & medicine 2024 Feb 20;212:336-348
SYNJ2BP ameliorates intervertebral disc degeneration by facilitating mitochondria-associated endoplasmic reticulum membrane formation and mitochondrial Zn(2+) homeostasis.
Song Y, Geng W, Zhu D, Liang H, Du Z, Tong B, Wang K, Li S, Gao Y, Feng X, Liao Z, Mei R, Yang C
Free radical biology & medicine 2024 Feb 20;212:220-233
Free radical biology & medicine 2024 Feb 20;212:220-233
Ezrin inhibition alleviates oxidative stress and pyroptosis via regulating TRPML1-calcineurin axis mediated enhancement of autophagy in spinal cord injury.
Lou J, Jin M, Zhou C, Fan Y, Ni L, Mao Y, Shen H, Li J, Zhang H, Fu C, Mao X, Chen Y, Zhong J, Zhou K, Wang L, Wu J
Free radical biology & medicine 2024 Feb 20;212:133-148
Free radical biology & medicine 2024 Feb 20;212:133-148
A Curcumin-Decorated Nanozyme with ROS Scavenging and Anti-Inflammatory Properties for Neuroprotection.
Gao F, Liang W, Chen Q, Chen B, Liu Y, Liu Z, Xu X, Zhu R, Cheng L
Nanomaterials (Basel, Switzerland) 2024 Feb 20;14(5)
Nanomaterials (Basel, Switzerland) 2024 Feb 20;14(5)
Transcriptotype-Driven Discovery of Apigenin as a Therapy against Cholestatic Liver Fibrosis: Through Inhibition of PANoptosis and Following Type-I Interferon Responses.
Duan S, Li X, Han J, Yang Y, Luo R, Cai Y, Li X, Zheng Q, Guo J, Liu R
Antioxidants (Basel, Switzerland) 2024 Feb 20;13(3)
Antioxidants (Basel, Switzerland) 2024 Feb 20;13(3)
The clustering status of detached gastric cancer cells inhibits anoikis-induced ferroptosis to promote metastatic colonization.
Sun J, Li J, Pantopoulos K, Liu Y, He Y, Kang W, Ye X
Cancer cell international 2024 Feb 18;24(1):77
Cancer cell international 2024 Feb 18;24(1):77
Tumorigenesis of basal muscle invasive bladder cancer was mediated by PTEN protein degradation resulting from SNHG1 upregulation.
Li T, Huang M, Sun N, Hua X, Chen R, Xie Q, Huang S, Du M, Zhao Y, Lin Q, Xu J, Han X, Zhao Y, Tian Z, Zhang Y, Chen W, Shen X, Huang C
Journal of experimental & clinical cancer research : CR 2024 Feb 17;43(1):50
Journal of experimental & clinical cancer research : CR 2024 Feb 17;43(1):50
Teadenol B as a Component of Microorganism-Fermented Tea Extract Inhibited Breast Cancers by Promoting Autophagy.
Zhao Y, Ding ZG, Yan YJ, Yang R, Qi MM, Pan SK, Xie JL, Sun YH, Xiang J
Molecules (Basel, Switzerland) 2024 Feb 16;29(4)
Molecules (Basel, Switzerland) 2024 Feb 16;29(4)
KLF2 controls proliferation and apoptosis of human spermatogonial stem cells via targeting GJA1.
Chen W, Cui Y, Li C, He C, Du L, Liu W, He Z
iScience 2024 Feb 16;27(2):109024
iScience 2024 Feb 16;27(2):109024
Investigating HMGB1 as a potential serum biomarker for early diabetic nephropathy monitoring by quantitative proteomics.
Peng R, Zuo S, Li X, Huang Y, Chen S, Zou X, Long H, Chen M, Yang Y, Yuan H, Zhao Q, Guo B, Liu L
iScience 2024 Feb 16;27(2):108834
iScience 2024 Feb 16;27(2):108834
Inhibition of RIPK1 alleviating vascular smooth muscle cells osteogenic transdifferentiation via Runx2.
Li Y, Jie W, Qi Y, Mo M, Lian Y, Yin L, Huang H
iScience 2024 Feb 16;27(2):108766
iScience 2024 Feb 16;27(2):108766
Total flavonoids of Astragalus protects glomerular filtration barrier in diabetic kidney disease.
Liu PY, Hong KF, Liu YD, Sun ZY, Zhao TT, Li XL, Lao CC, Tan SF, Zhang HY, Zhao YH, Xie Y, Xu YH
Chinese medicine 2024 Feb 16;19(1):27
Chinese medicine 2024 Feb 16;19(1):27
ALKBH5 promotes the development of lung adenocarcinoma by regulating the polarization of M2 macrophages through CDCA4.
Tan J, Chen F, Wang J, Li J, Ouyang B, Li X, Li Y, Zhang W, Jiang Y
Gene 2024 Feb 15;895:147975
Gene 2024 Feb 15;895:147975
Serine synthesis sustains macrophage IL-1β production via NAD(+)-dependent protein acetylation.
Wang C, Chen Q, Chen S, Fan L, Gan Z, Zhao M, Shi L, Bin P, Yang G, Zhou X, Ren W
Molecular cell 2024 Feb 15;84(4):744-759.e6
Molecular cell 2024 Feb 15;84(4):744-759.e6
Scutellarin targets Wnt5a against zearalenone-induced apoptosis in mouse granulosa cells in vitro and in vivo.
Sun N, Haseeb A, Sun P, Zhang H, Zhong J, Yin W, Fan K, Yang H, Zhang Z, Sun Y, Hu P, Li H
Journal of hazardous materials 2024 Feb 15;464:132917
Journal of hazardous materials 2024 Feb 15;464:132917
Lysine demethylase KDM3A alleviates hyperoxia-induced bronchopulmonary dysplasia in mice by promoting ETS1 expression.
Yang M, Chen Y, Huang X, Shen F, Meng Y
Experimental cell research 2024 Feb 15;435(2):113945
Experimental cell research 2024 Feb 15;435(2):113945
The levels of IL1RN is a factor influencing the onset of rheumatoid arthritis in non-alcoholic fatty liver disease.
Gu J, Xu J, Jiao A, Gao Z, Zhang C, Cai N, Xia S, Li J, Wang Z, Chen G, Liu X, Chen Y
International immunopharmacology 2024 Feb 15;128:111528
International immunopharmacology 2024 Feb 15;128:111528
L-lysine supplementation attenuates experimental autoimmune hepatitis in a chronic murine model.
Lei Y, Chen Y, Wang S, Lin Z, Han P, Tian D, Wang H, Liu M
Experimental animals 2024 Feb 14;73(1):83-92
Experimental animals 2024 Feb 14;73(1):83-92
PEDV inhibits HNRNPA3 expression by miR-218-5p to enhance cellular lipid accumulation and promote viral replication.
Shi X, Zhang Q, Yang N, Wang Q, Zhang Y, Xu X
mBio 2024 Feb 14;15(2):e0319723
mBio 2024 Feb 14;15(2):e0319723
Role of TFEB-autophagy lysosomal pathway in palmitic acid induced renal tubular epithelial cell injury.
Cai MY, Jiang XS, Wei YX, Wen RZ, Du XG
Biochemical and biophysical research communications 2024 Feb 12;696:149472
Biochemical and biophysical research communications 2024 Feb 12;696:149472
Exercise enhances placental labyrinth trophoblast development by activation of PGC-1α and FNDC5/irisin†.
Chae SA, Du M, Zhu MJ, Son JS
Biology of reproduction 2024 Feb 10;110(2):355-364
Biology of reproduction 2024 Feb 10;110(2):355-364
DNA hypomethylation-mediated upregulation of GADD45B facilitates airway inflammation and epithelial cell senescence in COPD.
Zhan Y, Huang Q, Deng Z, Chen S, Yang R, Zhang J, Zhang Y, Peng M, Wu J, Gu Y, Zeng Z, Xie J
Journal of advanced research 2024 Feb 10;
Journal of advanced research 2024 Feb 10;
OXCT1 functions as a succinyltransferase, contributing to hepatocellular carcinoma via succinylating LACTB.
Ma W, Sun Y, Yan R, Zhang P, Shen S, Lu H, Zhou Z, Jiang Z, Ye L, Mao Q, Xiong N, Jia W, Sun L, Gao P, Zhang H
Molecular cell 2024 Feb 1;84(3):538-551.e7
Molecular cell 2024 Feb 1;84(3):538-551.e7
POH1 induces Smad3 deubiquitination and promotes lung cancer metastasis.
Yuan Y, Li Y, Wu X, Bo J, Zhang L, Zhang J, Hu Y, Chen Y, Zeng Y, Wei X, Zhang H
Cancer letters 2024 Feb 1;582:216526
Cancer letters 2024 Feb 1;582:216526
TLR9 activation induces immunosuppression and tumorigenesis via PARP1/PD-L1 signaling pathway in oral squamous cell carcinoma.
Ma L, Qin N, Wan W, Song S, Hua S, Jiang C, Li N, Huang L, Gao X
American journal of physiology. Cell physiology 2024 Feb 1;326(2):C362-C381
American journal of physiology. Cell physiology 2024 Feb 1;326(2):C362-C381
Therapeutic application of human type 2 innate lymphoid cells via induction of granzyme B-mediated tumor cell death.
Li Z, Ma R, Tang H, Guo J, Shah Z, Zhang J, Liu N, Cao S, Marcucci G, Artis D, Caligiuri MA, Yu J
Cell 2024 Feb 1;187(3):624-641.e23
Cell 2024 Feb 1;187(3):624-641.e23
Leptin receptor deficiency impedes metabolic surgery related-weight loss through inhibition of energy expenditure in db/db mice.
Tong D, Xiang J, Liu W, Sun F, Wang L, Mou A, Cao T, Zhou Q, You M, Liao Y, Gao P, Liu D, Lu Z, Zhu Z
Diabetology & metabolic syndrome 2024 Feb 1;16(1):33
Diabetology & metabolic syndrome 2024 Feb 1;16(1):33
Tabersonine enhances cisplatin sensitivity by modulating Aurora kinase A and suppressing epithelial-mesenchymal transition in triple-negative breast cancer.
Chen X, Yan Y, Liu Y, Yi Q, Xu Z
Pharmaceutical biology 2024 Dec;62(1):394-403
Pharmaceutical biology 2024 Dec;62(1):394-403
Nanoparticles transfected with plasmid-encoded lncRNA-OIP5-AS1 inhibit renal ischemia-reperfusion injury in mice via the miR-410-3p/Nrf2 axis.
Zhang R, Zhang X, Zhu X, Li T, Li Y, Zhang P, Chen Y, Li G, Han X
Renal failure 2024 Dec;46(1):2319327
Renal failure 2024 Dec;46(1):2319327
Ginsenoside Rg1 mitigates cerebral ischaemia/reperfusion injury in mice by inhibiting autophagy through activation of mTOR signalling.
Xi ZC, Ren HG, Ai L, Wang Y, Liu MF, Qiu YF, Feng JL, Fu W, Bi QQ, Wang F, Xu HX
Acta pharmacologica Sinica 2024 Dec;45(12):2474-2486
Acta pharmacologica Sinica 2024 Dec;45(12):2474-2486
NOD2 contributes to Parvimonas micra-induced bone resorption in diabetic rats with experimental periodontitis.
Chen YY, Tan L, Su XL, Chen NX, Liu Q, Feng YZ, Guo Y
Molecular oral microbiology 2024 Dec;39(6):446-460
Molecular oral microbiology 2024 Dec;39(6):446-460
Novel isobavachalcone derivatives induce apoptosis and necroptosis in human non-small cell lung cancer H1975 cells.
Chen J, Zhao L, Xu MF, Huang D, Sun XL, Zhang YX, Li HM, Wu CZ
Journal of enzyme inhibition and medicinal chemistry 2024 Dec;39(1):2292006
Journal of enzyme inhibition and medicinal chemistry 2024 Dec;39(1):2292006
Ivacaftor attenuates gentamicin-induced ototoxicity through the CFTR-Nrf2-HO1/NQO1 pathway.
Hu R, Wu F, Zheng YQ
Redox report : communications in free radical research 2024 Dec;29(1):2332038
Redox report : communications in free radical research 2024 Dec;29(1):2332038
Integration of single-nucleus and exosome RNA sequencing dissected inter-cellular communication and biomarkers in pancreatic ductal adenocarcinoma.
Tang R, Zhang Z, Xu J, Wang W, Meng Q, Liu Y, Du Q, Liang C, Hua J, Zhang B, Yu X, Shi S
Computational and structural biotechnology journal 2024 Dec;23:1689-1704
Computational and structural biotechnology journal 2024 Dec;23:1689-1704
Downregulation of ABLIM3 confers to the metastasis of neuroblastoma via regulating the cell adhesion molecules pathway.
Gong B, Qu T, Zhang J, Jia Y, Song Z, Chen C, Yang J, Wang C, Liu Y, Jin Y, Cao W, Zhao Q
Computational and structural biotechnology journal 2024 Dec;23:1547-1561
Computational and structural biotechnology journal 2024 Dec;23:1547-1561
Study on chromatin regulation patterns of expression vectors in the PhiC31 integration site.
Liu X, Chen Q, Yin X, Wang X, Ran J, Yu W, Wang B
Epigenetics 2024 Dec;19(1):2337085
Epigenetics 2024 Dec;19(1):2337085
Molecular mechanism of infectious spleen and kidney necrosis virus in manipulating the hypoxia-inducible factor pathway to augment virus replication.
He J, Yu Y, Liu W, Li Z, Qi Z, Weng S, Guo C, He J
Virulence 2024 Dec;15(1):2349027
Virulence 2024 Dec;15(1):2349027
miR-10b-5p promotes tumor growth by regulating cell metabolism in liver cancer via targeting SLC38A2.
Xia M, Chen J, Hu Y, Qu B, Bu Q, Shen H
Cancer biology & therapy 2024 Dec 31;25(1):2315651
Cancer biology & therapy 2024 Dec 31;25(1):2315651
Deficiency of betaine-homocysteine methyltransferase activates glucose-6-phosphate dehydrogenase (G6PD) by decreasing arginine methylation of G6PD in hepatocellular carcinogenesis.
Gao J, Shi X, Sun Y, Liu X, Zhang F, Shi C, Yu X, Yan Z, Liu L, Yu S, Zhang J, Zhang X, Zhang S, Guo W
Science China. Life sciences 2024 Aug;67(8):1648-1665
Science China. Life sciences 2024 Aug;67(8):1648-1665
The combination of Butyricicoccus pullicaecorum and 3-hydroxyanthranilic acid prevents postmenopausal osteoporosis by modulating gut microbiota and Th17/Treg.
Zhu F, Liu H, Cao Y, Dai B, Wu H, Li W
European journal of nutrition 2024 Aug;63(5):1945-1959
European journal of nutrition 2024 Aug;63(5):1945-1959
Serum IL-24 combined with CA125 as screening and prognostic biomarkers for NSCLC.
Zhang K, Qu J, Deng S, Yuan E
Cell biology international 2024 Aug;48(8):1160-1168
Cell biology international 2024 Aug;48(8):1160-1168
Empagliflozin and liraglutide ameliorate HFpEF in mice via augmenting the Erbb4 signaling pathway.
Ni XY, Feng XJ, Wang ZH, Zhang Y, Little PJ, Cao Y, Xu SW, Tang LQ, Weng JP
Acta pharmacologica Sinica 2024 Aug;45(8):1604-1617
Acta pharmacologica Sinica 2024 Aug;45(8):1604-1617
Maresin1 alleviates neuroinflammation by inhibiting caspase-3/ GSDME-mediated pyroptosis in mice cerebral ischemia-reperfusion model.
Zhao M, Xian W, Liu W, Chen D, Wang S, Cao J
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2024 Aug;33(8):107789
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2024 Aug;33(8):107789
Identifying SLC2A6 as the novel protective factor in breast cancer by TP53-related genes affecting M1 macrophage infiltration.
Dai C, Man Y, Zhang L, Zhang X, Xie C, Wang S, Zhang Y, Guo Q, Zou L, Hong H, Jiang L, Shi Y
Apoptosis : an international journal on programmed cell death 2024 Aug;29(7-8):1211-1231
Apoptosis : an international journal on programmed cell death 2024 Aug;29(7-8):1211-1231
Blue light irradiation suppresses oral squamous cell carcinoma through induction of endoplasmic reticulum stress and mitochondrial dysfunction.
Jiang H, Fu Q, Yang J, Qin H, Li A, Liu S, Liu M
Journal of photochemistry and photobiology. B, Biology 2024 Aug;257:112963
Journal of photochemistry and photobiology. B, Biology 2024 Aug;257:112963
Homoplantaginin alleviates intervertebral disc degeneration by blocking the NF-κB/MAPK pathways via binding to TAK1.
Li B, Hu Y, Chen Y, Liu K, Rong K, Hua Q, Fu S, Yang X, Zhou T, Cheng X, Zhang K, Zhao J
Biochemical pharmacology 2024 Aug;226:116389
Biochemical pharmacology 2024 Aug;226:116389
FeP-Based Nanotheranostic Platform for Enhanced Phototherapy/Ferroptosis/Chemodynamic Therapy.
An N, Tang S, Wang Y, Luan J, Shi Y, Gao M, Guo C
Small (Weinheim an der Bergstrasse, Germany) 2024 Aug;20(32):e2309940
Small (Weinheim an der Bergstrasse, Germany) 2024 Aug;20(32):e2309940
Lipoamide Attenuates Hypertensive Myocardial Hypertrophy Through PI3K/Akt-Mediated Nrf2 Signaling Pathway.
Cao H, Zhao L, Yuan Y, Liao C, Zeng W, Li A, Huang Q, Zhao Y, Fan Y, Jiang L, Song D, Li S, Zhang B
Journal of cardiovascular translational research 2024 Aug;17(4):910-922
Journal of cardiovascular translational research 2024 Aug;17(4):910-922
Hypobaric hypoxia causes low fecundity in zebrafish parents and impairment of skeletal development in zebrafish embryos and rat offspring.
Chen C, Wang X, Li Y, Zhao T, Wang H, Gao Y, Feng Y, Wang J, Shang L, Wang Y, Zhao B, Dong W
Reproductive toxicology (Elmsford, N.Y.) 2024 Aug;127:108603
Reproductive toxicology (Elmsford, N.Y.) 2024 Aug;127:108603
Reversing MET-Mediated Resistance in Oncogene-Driven NSCLC by MET-Activated Wnt Condensative Prodrug.
Liu N, Zheng X, Yan J, Jiang A, Yao Y, He W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(30):e2400603
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(30):e2400603
Loss of NLRP6 expression increases the severity of intestinal injury after syngeneic hematopoietic stem cell transplantation.
Zhu S, Zhang X, Xu K, Liang J, Wang W, Zeng L, Xu K
Annals of hematology 2024 Aug;103(8):3145-3154
Annals of hematology 2024 Aug;103(8):3145-3154
Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer.
Jiang Y, Wang Y, Chen G, Sun F, Wu Q, Huang Q, Zeng D, Qiu W, Wang J, Yao Z, Liang B, Li S, Wu J, Huang N, Wang Y, Chen J, Zhai X, Huang L, Xu B, Yamamoto M, Tsukamoto T, Nomura S, Liao W, Shi M
Cell metabolism 2024 Aug 6;36(8):1806-1822.e11
Cell metabolism 2024 Aug 6;36(8):1806-1822.e11
Recharacterization of RSL3 reveals that the selenoproteome is a druggable target in colorectal cancer.
DeAngelo SL, Zhao L, Dziechciarz S, Shin M, Solanki S, Balia A, El-Derany MO, Castillo C, Qin Y, Das NK, Bell HN, Paulo JA, Zhang Y, Rossiter NJ, McCulla EC, He J, Talukder I, Ng BW, Schafer ZT, Neamati N, Mancias JD, Koutmos M, Shah YM
bioRxiv : the preprint server for biology 2024 Aug 27;
bioRxiv : the preprint server for biology 2024 Aug 27;
Nicotinamide riboside ameliorates survival time and motor dysfunction in an MPTP-Induced Parkinson's disease zebrafish model through effects on glucose metabolism and endoplasmic reticulum stress.
Luo Q, Yang Y, Xian C, Zhou P, Zhang H, Lv Z, Liu J
Chemico-biological interactions 2024 Aug 25;399:111118
Chemico-biological interactions 2024 Aug 25;399:111118
Neural epidermal growth factor-like 1 protein (Nell-1) alleviates periodontal tissue destruction in periodontitis by regulating the ratio of M2/M1 macrophage phenotypes.
Ni C, Liao W, Nie H, Ge R, Liu R, Zou X, Yuan Z, Yan F
International immunopharmacology 2024 Aug 20;137:112522
International immunopharmacology 2024 Aug 20;137:112522
A novel oral TLR7 agonist orchestrates immune response and synergizes with PD-L1 blockade via type I IFN pathway in lung cancer.
Zuo X, Cheng Q, Wang Z, Liu J, Lu W, Wu G, Zhu S, Liu X, Lv T, Song Y
International immunopharmacology 2024 Aug 20;137:112478
International immunopharmacology 2024 Aug 20;137:112478
Azithromycin regulates Mettl3-mediated NF-κB pathway to enhance M2 polarization of RAW264.7 macrophages and attenuate LPS-triggered cytotoxicity of MLE-12 alveolar cells.
Xu S, Xing J, Zheng L, Su H, Zou Y, Niu Y, Di H
International immunopharmacology 2024 Aug 20;137:112426
International immunopharmacology 2024 Aug 20;137:112426
Diosgenin attenuates nonalcoholic hepatic steatosis through the hepatic SIRT1/PGC-1α pathway.
Meng D, Yin G, Chen S, Zhang X, Yu W, Wang L, Liu H, Jiang W, Sun Y, Zhang F
European journal of pharmacology 2024 Aug 15;977:176737
European journal of pharmacology 2024 Aug 15;977:176737
Nrf2 expression, mitochondrial fission, and neuronal apoptosis in the prefrontal cortex of methamphetamine abusers and rats.
Nie QY, Yang GM, Zhang P, Dong WJ, Jing D, Hou ZP, Peng YX, Yu Y, Li LH, Hong SJ
Brain research 2024 Aug 15;1837:148973
Brain research 2024 Aug 15;1837:148973
The mechanism of extracellular CypB promotes glioblastoma adaptation to glutamine deprivation microenvironment.
Yin H, Liu Y, Dong Q, Wang H, Yan Y, Wang X, Wan X, Yuan G, Pan Y
Cancer letters 2024 Aug 10;597:216862
Cancer letters 2024 Aug 10;597:216862
Fusobacterium nucleatum induces oxaliplatin resistance by inhibiting ferroptosis through E-cadherin/β-catenin/GPX4 axis in colorectal cancer.
Li B, Wei Z, Wang Z, Xu F, Yang J, Lin B, Chen Y, Wenren H, Wu L, Guo X, Liu Y, Wei Y
Free radical biology & medicine 2024 Aug 1;220:125-138
Free radical biology & medicine 2024 Aug 1;220:125-138
Neuritin promotes autophagic flux by inhibiting the cGAS-STING pathway to alleviate brain injury after subarachnoid haemorrhage.
Zhang H, Ren K, Hu Y, Liu B, He Y, Xu H, Ma K, Tian W, Dai L, Zhao D
Brain research 2024 Aug 1;1836:148909
Brain research 2024 Aug 1;1836:148909
Altered vacuole membrane protein 1 (VMP1) expression is associated with increased NLRP3 inflammasome activation and mitochondrial dysfunction.
Zack SR, Venkatesan M, Nikolaienko R, Cook B, Melki R, Zima AV, Campbell EM
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Apr;73(4):563-580
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Apr;73(4):563-580
Insertion of a neomycin selection cassette in the Amigo1 locus alters gene expression in the olfactory epithelium leading to region-specific defects in olfactory receptor neuron development.
Raja R, Dumontier E, Phen A, Cloutier JF
Genesis (New York, N.Y. : 2000) 2024 Apr;62(2):e23594
Genesis (New York, N.Y. : 2000) 2024 Apr;62(2):e23594
ZFP541 and KCTD19 regulate chromatin organization and transcription programs for male meiotic progression.
Zhou X, Fang K, Liu Y, Li W, Tan Y, Zhang J, Yu X, Wang G, Zhang Y, Shang Y, Zhang L, Chen CD, Wang S
Cell proliferation 2024 Apr;57(4):e13567
Cell proliferation 2024 Apr;57(4):e13567
Crosstalk between autophagy and inflammasomes in ricin-induced inflammatory injury.
Zhang S, Zhao N, Song S, Wang Y, Wang Y, Sun C, Dong M, Huo M, Xu N, Liu W, Li G
Toxicology and applied pharmacology 2024 Apr;485:116890
Toxicology and applied pharmacology 2024 Apr;485:116890
Vinpocetine represses the progression of nonalcoholic steatohepatitis in mice by mediating inflammasome components via NF-κB signaling.
Zhu Y, Tang H, Zhao H, Lu J, Lin K, Ni J, Zhao B, Wu G, Tan C
Gastroenterologia y hepatologia 2024 Apr;47(4):366-376
Gastroenterologia y hepatologia 2024 Apr;47(4):366-376
Upregulation of UHRF1 Promotes PINK1-mediated Mitophagy to Alleviates Ferroptosis in Diabetic Nephropathy.
Ji H, Zhao Y, Ma X, Wu L, Guo F, Huang F, Song Y, Wang J, Qin G
Inflammation 2024 Apr;47(2):718-732
Inflammation 2024 Apr;47(2):718-732
Britannin as a novel NLRP3 inhibitor, suppresses inflammasome activation in macrophages and alleviates NLRP3-related diseases in mice.
Shao JJ, Li WF, Sun JF, Zhuang ZS, Min JL, Long XH, Wu GJ, Xu HW, Liang G
Acta pharmacologica Sinica 2024 Apr;45(4):803-814
Acta pharmacologica Sinica 2024 Apr;45(4):803-814
Mechanisms of Dangua Fang in multi-target and multi-method regulation of glycolipid metabolism based on phosphoproteomics.
Xianpei H, Zhita W, Liang LI, Liuqing Y, Suping H, Lang J, Weidong HE
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2024 Apr;44(2):334-344
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2024 Apr;44(2):334-344
Propofol-induced LINC01133 inhibits the progression of colorectal cancer via miR-186-5p/NR3C2 axis.
Yao Y, Zhang F, Liu F, Xia D
Environmental toxicology 2024 Apr;39(4):2265-2284
Environmental toxicology 2024 Apr;39(4):2265-2284
Polystyrene microplastics mediate cell cycle arrest, apoptosis, and autophagy in the G2/M phase through ROS in grass carp kidney cells.
Lu H, Hou L, Zhang Y, Guo T, Wang Y, Xing M
Environmental toxicology 2024 Apr;39(4):1923-1935
Environmental toxicology 2024 Apr;39(4):1923-1935
Efficient gene delivery by multifunctional star poly (β-amino ester)s into difficult-to-transfect macrophages for M1 polarization.
Bo T, Wang C, Yao D, Jiang Q, Zhao Y, Wang F, He W, Xu W, Zhou H, Li M, Zhang S, Xue R
Journal of controlled release : official journal of the Controlled Release Society 2024 Apr;368:157-169
Journal of controlled release : official journal of the Controlled Release Society 2024 Apr;368:157-169
Lysosomal destabilization: A missing link between pathological calcification and osteoarthritis.
Ye T, Wang C, Yan J, Qin Z, Qin W, Ma Y, Wan Q, Lu W, Zhang M, Tay FR, Jiao K, Niu L
Bioactive materials 2024 Apr;34:37-50
Bioactive materials 2024 Apr;34:37-50
Construction of a versatile fusion protein for targeted therapy and immunotherapy.
Huang XS, Yang LT, Yang K, Zhou H, Abudureheman T, Zheng WW, Chen KM, Duan CW
Protein science : a publication of the Protein Society 2024 Apr;33(4):e4944
Protein science : a publication of the Protein Society 2024 Apr;33(4):e4944
Novel α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor (AMPAR) potentiator LT-102: A promising therapeutic agent for treating cognitive impairment associated with schizophrenia.
Qi X, Yu X, Wei L, Jiang H, Dong J, Li H, Wei Y, Zhao L, Deng W, Guo W, Hu X, Li T
CNS neuroscience & therapeutics 2024 Apr;30(4):e14713
CNS neuroscience & therapeutics 2024 Apr;30(4):e14713
Integrated transcriptomic and proteomic profiling reveals the key molecular signatures of brain endothelial reperfusion injury.
Ji Y, Chen Y, Tan X, Huang X, Gao Q, Ma Y, Yang S, Yin M, Yu M, Fang C, Wang Y, Shi Z, Chang J
CNS neuroscience & therapeutics 2024 Apr;30(4):e14483
CNS neuroscience & therapeutics 2024 Apr;30(4):e14483
Isorhamnetin Downregulates MMP2 and MMP9 to Inhibit Development of Rheumatoid Arthritis through SRC/ERK/CREB Pathway.
Liu XR, Li SF, Mei WY, Liu XD, Zhou RB
Chinese journal of integrative medicine 2024 Apr;30(4):299-310
Chinese journal of integrative medicine 2024 Apr;30(4):299-310
Oxidative stress-induced changes in the transcriptomic profile of extracellular vesicles.
Dellar ER, Hill C, Carter DRF, Baena-Lopez LA
Journal of extracellular biology 2024 Apr;3(4):e150
Journal of extracellular biology 2024 Apr;3(4):e150
Abnormal activation of RFC3, A YAP1/TEAD downstream target, promotes gastric cancer progression.
Guo Z, Guo L
International journal of clinical oncology 2024 Apr;29(4):442-455
International journal of clinical oncology 2024 Apr;29(4):442-455
Cathepsin L prevents the accumulation of alpha-synuclein fibrils in the cell.
Matsuki A, Watanabe Y, Hashimoto S, Hoshino A, Matoba S
Genes to cells : devoted to molecular & cellular mechanisms 2024 Apr;29(4):328-336
Genes to cells : devoted to molecular & cellular mechanisms 2024 Apr;29(4):328-336
Investigation of GPR143 as a promising novel marker for the progression of skin cutaneous melanoma through bioinformatic analyses and cell experiments.
Bai R, Yin P, Xing Z, Wu S, Zhang W, Ma X, Gan X, Liang Y, Zang Q, Lei H, Wei Y, Zhang C, Dai B, Zheng Y
Apoptosis : an international journal on programmed cell death 2024 Apr;29(3-4):372-392
Apoptosis : an international journal on programmed cell death 2024 Apr;29(3-4):372-392
HBI-8000 improves heart failure with preserved ejection fraction via the TGF-β1/MAPK signalling pathway.
Tian J, Li W, Zeng L, Li Y, Du J, Li Y, Li B, Su G
Journal of cellular and molecular medicine 2024 Apr;28(7):e18238
Journal of cellular and molecular medicine 2024 Apr;28(7):e18238
Retinoic acid induced specific changes in the phosphoproteome of C17.2 neural stem cells.
Zhang C, Ge L, Xie H, Liu X, Xun C, Chen Y, Chen H, Lu M, Chen P
Journal of cellular and molecular medicine 2024 Apr;28(7):e18205
Journal of cellular and molecular medicine 2024 Apr;28(7):e18205
Lipin-1 deficiency deteriorates defect of fatty acid β-oxidation and lipid-related kidney damage in diabetic kidney disease.
Lin S, Wang L, Jia Y, Sun Y, Qiao P, Quan Y, Liu J, Hu H, Yang B, Zhou H
Translational research : the journal of laboratory and clinical medicine 2024 Apr;266:1-15
Translational research : the journal of laboratory and clinical medicine 2024 Apr;266:1-15
Polyvinyl alcohol/carboxymethyl chitosan-based hydrogels loaded with taxifolin liposomes promote diabetic wound healing by inhibiting inflammation and regulating autophagy.
Ding Q, Liu X, Liu X, Chai G, Wang N, Ma S, Zhang L, Zhang S, Yang J, Wang Y, Shen L, Ding C, Liu W
International journal of biological macromolecules 2024 Apr;263(Pt 1):130226
International journal of biological macromolecules 2024 Apr;263(Pt 1):130226
A Pt(II) complex bearing N-heterocycle ring induced ferroptotic cell death in ovarian cancer.
Shen X, Peng Y, Zhou H, Ye X, Han Z, Shi X
Journal of inorganic biochemistry 2024 Apr;253:112502
Journal of inorganic biochemistry 2024 Apr;253:112502
Excessive processing and acetylation of OPA1 aggravate age-related hearing loss via the dysregulation of mitochondrial dynamics.
Zhang A, Pan Y, Wang H, Ding R, Zou T, Guo D, Shen Y, Ji P, Huang W, Wen Q, Wang Q, Hu H, Wu J, Xiang M, Ye B
Aging cell 2024 Apr;23(4):e14091
Aging cell 2024 Apr;23(4):e14091
The NLRX1-SLC39A7 complex orchestrates mitochondrial dynamics and mitophagy to rejuvenate intervertebral disc by modulating mitochondrial Zn(2+) trafficking.
Song Y, Liang H, Li G, Ma L, Zhu D, Zhang W, Tong B, Li S, Gao Y, Wu X, Zhang Y, Feng X, Wang K, Yang C
Autophagy 2024 Apr;20(4):809-829
Autophagy 2024 Apr;20(4):809-829
DDIT3/CHOP promotes LPS/ATP-induced pyroptosis in osteoblasts via mitophagy inhibition.
Dong Z, Yang B, Jia M, Yang C, Wang S, Mu H, Wang J
Biochimica et biophysica acta. Molecular cell research 2024 Apr;1871(4):119712
Biochimica et biophysica acta. Molecular cell research 2024 Apr;1871(4):119712
The regulatory role of the apelin/APJ axis in scarring: Identification of upstream and downstream mechanisms.
Shi N, Wang Y, Xia Z, Zhang J, Jia S, Jiao Y, Wang C, Wang X, Zhao J, Zhang J, Jiang D
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167125
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167125
Discovery of 2,8-dihydroxyadenine in HUA patients with uroliths and biomarkers for its associated nephropathy.
Zheng X, Lu X, Li Q, Gong S, Chen B, Xie Q, Yan F, Li J, Su Z, Liu Y, Guo Z, Chen J, Li Y
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167051
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167051
LCP1-mediated cytoskeleton alterations involve in arsenite-triggered malignant phenotype of human immortalized prostate stromal cells.
Yang Y, Zhou M, Huang Y, Ye X, Mo Y, Huang Y, Wang S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114548
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114548
Development of a therapeutic monoclonal antibody against circulating adipocyte fatty acid binding protein to treat ischaemic stroke.
Liao B, Yang S, Geng L, Zong J, Zhang Z, Jiang M, Jiang X, Li S, Xu A, Chang J, Hoo RLC
British journal of pharmacology 2024 Apr;181(8):1238-1255
British journal of pharmacology 2024 Apr;181(8):1238-1255
Trilobatin attenuates cerebral ischaemia/reperfusion-induced blood-brain barrier dysfunction by targeting matrix metalloproteinase 9: The legend of a food additive.
Feng L, Li Y, Lin M, Xie D, Luo Y, Zhang Y, He Z, Gong Q, Zhun ZY, Gao J
British journal of pharmacology 2024 Apr;181(7):1005-1027
British journal of pharmacology 2024 Apr;181(7):1005-1027
Chidamide improves gefitinib treatment outcomes in NSCLC by attenuating recruitment and immunosuppressive function of myeloid-derived suppressor cells.
Shao J, Ye Z, Shen Z, Liu N, Zhang L, Tachibana M, Xie Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Apr;173:116306
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Apr;173:116306
Iron overload increases the sensitivity of endometriosis stromal cells to ferroptosis via a PRC2-independent function of EZH2.
Luo Y, Li L, Hu Q, Zhang Z, Liu F, Peng Y, Zou Y, Chen L
The international journal of biochemistry & cell biology 2024 Apr;169:106553
The international journal of biochemistry & cell biology 2024 Apr;169:106553
Design, synthesis, and biological evaluation of gambogenic acid derivatives: Unraveling their anti-cancer effects by inducing pyroptosis.
Huang Q, Guo K, Ren Y, Tan J, Ren Y, Zhang L, Zheng C, Xu H
Bioorganic chemistry 2024 Apr;145:107182
Bioorganic chemistry 2024 Apr;145:107182
NF-κB affected the serum levels of TNF-α and IL-1β via activation of the MAPK/NF-κB signaling pathway in rat model of acute pulmonary microthromboembolism.
Zhong Y, Liang B, Zhang X, Li J, Zeng D, Huang T, Wu J
Pulmonary circulation 2024 Apr;14(2):e12357
Pulmonary circulation 2024 Apr;14(2):e12357
Nanointegrative Glycoengineering-Activated Necroptosis of Triple Negative Breast Cancer Stem Cells Enables Self-Amplifiable Immunotherapy for Systemic Tumor Rejection.
Zhao Y, Li Y, He J, Li M, Yao X, Yang H, Luo Z, Luo P, Su M
Advanced healthcare materials 2024 Apr;13(9):e2303337
Advanced healthcare materials 2024 Apr;13(9):e2303337
Xanthohumol ameliorates drug-induced hepatic ferroptosis via activating Nrf2/xCT/GPX4 signaling pathway.
Deng Y, Chu X, Li Q, Zhu G, Hu J, Sun J, Zeng H, Huang J, Ge G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155458
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155458
Preparation and characterisation of baicalin magnesium and its protective effect in ulcerative colitis via gut microbiota-bile acid axis modulation.
Zhang L, Miao C, Wang Z, Guan X, Ma Y, Song J, Shen S, Song H, Li M, Liu C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155416
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155416
Tiliroside attenuates acute kidney injury by inhibiting ferroptosis through the disruption of NRF2-KEAP1 interaction.
Cai F, Li D, Zhou K, Zhang W, Yang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155407
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155407
Cadmium disrupts spermatogenic cell cycle via piRNA-DQ717867/p53 pathway.
Wei J, Dai J, Shi X, Zhao R, Fu G, Li R, Xia C, Zhang L, Zhou T, Wang H, Shi Y
Reproductive toxicology (Elmsford, N.Y.) 2024 Apr;125:108554
Reproductive toxicology (Elmsford, N.Y.) 2024 Apr;125:108554
Histone deacetylase 6 suppression of renal tubular epithelial cell promotes interstitial mineral deposition via alpha-tubulin acetylation.
Li S, Wu W, Yang B, Liu Z, Duan X, Sun X, Liu H, Zhang S, Zhou Y, Wu W
Cellular signalling 2024 Apr;116:111057
Cellular signalling 2024 Apr;116:111057
Beta-Cell Tipe1 Orchestrates Insulin Secretion and Cell Proliferation by Promoting Gαs/cAMP Signaling via USP5.
Ding L, Sun Y, Liang Y, Zhang J, Fu Z, Ren C, Li P, Liu W, Xiao R, Wang H, Zhang Z, Yue X, Li C, Wu Z, Feng Y, Liang X, Ma C, Gao L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(16):e2304940
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(16):e2304940
Baicalin inhibits monosodium urate crystal-induced pyroptosis in renal tubular epithelial cell line through Panx-1/P2X7 pathways: Molecular docking, molecular dynamics, and in vitro experiments.
Fu W, Liu Z, Wang Y, Li X, Yu X, Li Y, Yu Z, Qiu Y, Mei Z, Xu L
Chemical biology & drug design 2024 Apr;103(4):e14522
Chemical biology & drug design 2024 Apr;103(4):e14522
PPARγ alleviates preeclampsia development by regulating lipid metabolism and ferroptosis.
Lai W, Yu L, Deng Y
Communications biology 2024 Apr 9;7(1):429
Communications biology 2024 Apr 9;7(1):429
Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8(+) T cell effector functions.
Cong J, Liu P, Han Z, Ying W, Li C, Yang Y, Wang S, Yang J, Cao F, Shen J, Zeng Y, Bai Y, Zhou C, Ye L, Zhou R, Guo C, Cang C, Kasper DL, Song X, Dai L, Sun L, Pan W, Zhu S
Immunity 2024 Apr 9;57(4):876-889.e11
Immunity 2024 Apr 9;57(4):876-889.e11
Occludin and collagen IV degradation mediated by the T9SS effector SspA contributes to blood-brain barrier damage in ducks during Riemerella anatipestifer infection.
Chen Z, Zhu M, Liu D, Wu M, Niu P, Yu Y, Ding C, Yu S
Veterinary research 2024 Apr 9;55(1):49
Veterinary research 2024 Apr 9;55(1):49
Hesperidin ameliorates H(2)O(2)-induced bovine mammary epithelial cell oxidative stress via the Nrf2 signaling pathway.
Huang Q, Liu J, Peng C, Han X, Tan Z
Journal of animal science and biotechnology 2024 Apr 9;15(1):57
Journal of animal science and biotechnology 2024 Apr 9;15(1):57
LDL receptor-related protein 5 selectively transports unesterified polyunsaturated fatty acids to intracellular compartments.
Tang W, Luan Y, Yuan Q, Li A, Chen S, Menacherry S, Young L, Wu D
Nature communications 2024 Apr 9;15(1):3068
Nature communications 2024 Apr 9;15(1):3068
Activation of the IKK2/NF-κB pathway in VSMCs inhibits calcified vascular stiffness in CKD.
Miyazaki-Anzai S, Masuda M, Keenan AL, Shiozaki Y, Miranda JG, Miyazaki M
JCI insight 2024 Apr 8;9(7)
JCI insight 2024 Apr 8;9(7)
MiR-574-5p activates human TLR8 to promote autoimmune signaling and lupus.
Wang T, Song D, Li X, Luo Y, Yang D, Liu X, Kong X, Xing Y, Bi S, Zhang Y, Hu T, Zhang Y, Dai S, Shao Z, Chen D, Hou J, Ballestar E, Cai J, Zheng F, Yang JY
Cell communication and signaling : CCS 2024 Apr 8;22(1):220
Cell communication and signaling : CCS 2024 Apr 8;22(1):220
NBR1-p62-Nrf2 mediates the anti-pulmonary fibrosis effects of protodioscin.
Zeng Q, Wen BB, Liu X, Luo YY, Hu ZG, Huang L, Zhang XH, Huang XT, Zhou TT, Sang XX, Luo YY, Xiong DY, Luo ZQ, Liu W, Tang SY
Chinese medicine 2024 Apr 8;19(1):60
Chinese medicine 2024 Apr 8;19(1):60
ATP Citrate Lyase is a General Tumour Biomarker and Contributes to the Development of Cutaneous Squamous Cell Carcinoma.
Luo R, Huang Y, Bai R, Liu M, Sun L, Wang X, Zheng Y
Acta dermato-venereologica 2024 Apr 8;104:adv23805
Acta dermato-venereologica 2024 Apr 8;104:adv23805
Mulberry (Morus alba L.) leaf water extract attenuates type 2 diabetes mellitus by regulating gut microbiota dysbiosis, lipopolysaccharide elevation and endocannabinoid system disorder.
Du Y, Zhang R, Zheng XX, Zhao YL, Chen YL, Ji S, Guo MZ, Tang DQ
Journal of ethnopharmacology 2024 Apr 6;323:117681
Journal of ethnopharmacology 2024 Apr 6;323:117681
Jiawei Buzhong Yiqi decoction ameliorates polycystic ovary syndrome via oocyte-granulosa cell communication.
Hu R, Huang Y, Geng Y, Liu Z, Li F, Zhang Z, Ma W, Song K, Dong H, Song Y, Zhang M
Journal of ethnopharmacology 2024 Apr 6;323:117654
Journal of ethnopharmacology 2024 Apr 6;323:117654
Systematic HOIP interactome profiling reveals critical roles of linear ubiquitination in tissue homeostasis.
Fu Y, Li L, Zhang X, Deng Z, Wu Y, Chen W, Liu Y, He S, Wang J, Xie Y, Tu Z, Lyu Y, Wei Y, Wang S, Cui CP, Liu CH, Zhang L
Nature communications 2024 Apr 6;15(1):2974
Nature communications 2024 Apr 6;15(1):2974
The role of mTORC1/TFEB axis mediated lysosomal biogenesis and autophagy impairment in fluoride neurotoxicity and the intervention effects of resveratrol.
Tang H, Hou H, Song L, Tian Z, Liu W, Xia T, Wang A
Journal of hazardous materials 2024 Apr 5;467:133634
Journal of hazardous materials 2024 Apr 5;467:133634
Identification of HK3 as a promising immunomodulatory and prognostic target in sepsis-induced acute lung injury.
Zhu M, Tang X, Xu J, Gong Y
Biochemical and biophysical research communications 2024 Apr 30;706:149759
Biochemical and biophysical research communications 2024 Apr 30;706:149759
Mycobacterium tuberculosis PE_PGRS38 Enhances Intracellular Survival of Mycobacteria by Inhibiting TLR4/NF-κB-Dependent Inflammation and Apoptosis of the Host.
Ullah H, Shi X, Taj A, Cheng L, Yan Q, Sha S, Ahmad, Kang J, Haris M, Ma X, Ma Y
Biology 2024 Apr 30;13(5)
Biology 2024 Apr 30;13(5)
E2F-mediated POLA2 upregulation is correlated with macrophage infiltration and poor prognosis in hepatocellular carcinoma.
Teng Y, Liu R
Translational cancer research 2024 Apr 30;13(4):1848-1860
Translational cancer research 2024 Apr 30;13(4):1848-1860
Baicalin reduces inflammation to inhibit lung cancer via targeting SOCS1/NF-κB/STAT3 axis.
Guo L, Yue M, Ma C, Wang Y, Hou J, Li H
Heliyon 2024 Apr 30;10(8):e29361
Heliyon 2024 Apr 30;10(8):e29361
Epigenetic regulation of FOXI2 promotes clear cell renal cell carcinoma progression.
Zhou S, Cheng C, Liao YX, Wang L, Zeng JM, Zhou FF, Zhang XQ, Yang T
Heliyon 2024 Apr 30;10(8):e29218
Heliyon 2024 Apr 30;10(8):e29218
Phthalates Induce Neurotoxicity by Disrupting the Mfn2-PERK Axis-Mediated Endoplasmic Reticulum-Mitochondria Interaction.
Zhao Y, Chang YH, Ren HR, Lou M, Jiang FW, Wang JX, Chen MS, Liu S, Shi YS, Zhu HM, Li JL
Journal of agricultural and food chemistry 2024 Apr 3;72(13):7411-7422
Journal of agricultural and food chemistry 2024 Apr 3;72(13):7411-7422
Expression of Multicopy Tandem Recombinant Ginseng Hexapeptide in Bacillus subtilis and the Evaluation of Antiaging Activity.
Xiang Q, Qu L, Lei H, Duan Z, Zhu C, Yuwen W, Ma X, Fan D
Journal of agricultural and food chemistry 2024 Apr 3;72(13):7266-7278
Journal of agricultural and food chemistry 2024 Apr 3;72(13):7266-7278
Rapamycin alleviates irradiation-induced parotid injury by enhancing the whole gland homeostasis.
Zhu Z, Song J, Zhang C, Zhang J, Shan Z
Oral diseases 2024 Apr 3;
Oral diseases 2024 Apr 3;
CD63(+) cancer-associated fibroblasts confer CDK4/6 inhibitor resistance to breast cancer cells by exosomal miR-20.
Sun J, Du R, Li X, Liu C, Wang D, He X, Li G, Zhang K, Wang S, Hao Q, Zhang Y, Li M, Gao Y, Zhang C
Cancer letters 2024 Apr 28;588:216747
Cancer letters 2024 Apr 28;588:216747
Proteomics Identifies LUC7L3 as a Prognostic Biomarker for Hepatocellular Carcinoma.
Hou Y, Wang S, Zhang Y, Huang X, Zhang X, He F, Tian C, Sun A
Current issues in molecular biology 2024 Apr 27;46(5):4004-4020
Current issues in molecular biology 2024 Apr 27;46(5):4004-4020
Agomirs upregulating carboxypeptidase E expression rescue hippocampal neurogenesis and memory deficits in Alzheimer's disease.
Jiang D, Liu H, Li T, Zhao S, Yang K, Yao F, Zhou B, Feng H, Wang S, Shen J, Tang J, Zhang YX, Wang Y, Guo C, Tang TS
Translational neurodegeneration 2024 Apr 26;13(1):24
Translational neurodegeneration 2024 Apr 26;13(1):24
Sphingolipid biosynthesis is essential for metabolic rewiring during T(H)17 cell differentiation.
Abimannan T, Parthibane V, Le SH, Vijaykrishna N, Fox SD, Karim B, Kunduri G, Blankenberg D, Andresson T, Bamba T, Acharya U, Acharya JK
Science advances 2024 Apr 26;10(17):eadk1045
Science advances 2024 Apr 26;10(17):eadk1045
Expression and functional significance of phosphoenolpyruvate carboxykinase 1 in uveal melanoma.
Bi HE, Zhang J, Yao Y, Wang S, Yao J, Shao Z, Jiang Q
Cell death discovery 2024 Apr 26;10(1):196
Cell death discovery 2024 Apr 26;10(1):196
Peptide Inhibitor Targeting the Extraterminal Domain in BRD4 Potently Suppresses Breast Cancer Both In Vitro and In Vivo.
Huang QX, Fan DM, Zheng ZZ, Ran T, Bai A, Xiao RQ, Hu GS, Liu W
Journal of medicinal chemistry 2024 Apr 25;67(8):6658-6672
Journal of medicinal chemistry 2024 Apr 25;67(8):6658-6672
Structure-Guided Discovery and Preclinical Assessment of Novel (Thiophen-3-yl)aminopyrimidine Derivatives as Potent ERK1/2 Inhibitors.
Shuai W, Xiao H, Yang P, Zhang Y, Bu F, Wu Y, Sun Q, Wang G, Ouyang L
Journal of medicinal chemistry 2024 Apr 25;67(8):6425-6455
Journal of medicinal chemistry 2024 Apr 25;67(8):6425-6455
Pterostilbene nanoemulsion promotes Nrf2 signaling pathway to downregulate oxidative stress for treating Alzheimer's disease.
Liu J, Xu J, Jia L, Zhou Y, Fu Q, Wang Y, Mu D, Wang D, Li N, Hou Y
International journal of pharmaceutics 2024 Apr 25;655:124002
International journal of pharmaceutics 2024 Apr 25;655:124002
Abrogation of KLF5 sensitizes BRCA1-proficient pancreatic cancer to PARP inhibition.
Zhang Z, Liu Y, Xu Y, Xu Z, Jia J, Jin Y, Wang W, Liu L
Acta biochimica et biophysica Sinica 2024 Apr 25;56(4):576-585
Acta biochimica et biophysica Sinica 2024 Apr 25;56(4):576-585
Norcantharidin Enhances the Antitumor Effect of 5-Fluorouracil by Inducing Apoptosis of Cervical Cancer Cells: Network Pharmacology, Molecular Docking, and Experimental Validation.
Huang Y, Wan XW, Du YT, Feng Y, Yang LS, Liu YB, Chen T, Zhu Z, Xu YT, Wang CC
Current issues in molecular biology 2024 Apr 25;46(5):3906-3918
Current issues in molecular biology 2024 Apr 25;46(5):3906-3918
Association of Cadherin-Related Family Member 1 with Traumatic Brain Injury.
Jiang Y, Chen P, Zhao Y, Zhang Y
Cellular and molecular neurobiology 2024 Apr 24;44(1):41
Cellular and molecular neurobiology 2024 Apr 24;44(1):41
Anti-hepatocellular carcinoma activity of Sorbaria sorbifolia by regulating VEGFR and c-Met/apoptotic pathway.
Xu ZH, Dang Y, Dong Y, Dong CY, Liu Y, Chen X, Yao Z, Shi JP
Journal of ethnopharmacology 2024 Apr 24;324:117758
Journal of ethnopharmacology 2024 Apr 24;324:117758
Leech extract alleviates idiopathic pulmonary fibrosis by TGF-β1/Smad3 signaling pathway.
Zhang Y, Lu YB, Zhu WJ, Gong XX, Qian R, Lu YJ, Li Y, Yao WF, Bao BH, Zhang Y, Zhang L, Cheng FF
Journal of ethnopharmacology 2024 Apr 24;324:117737
Journal of ethnopharmacology 2024 Apr 24;324:117737
Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome.
Wu S, Dai X, Xia Y, Zhao Q, Zhao H, Shi Z, Yin X, Liu X, Zhang A, Yao Z, Zhang H, Li Q, Thorne RF, Zhang S, Sheng W, Hu W, Gu H
Cell reports 2024 Apr 23;43(4):114111
Cell reports 2024 Apr 23;43(4):114111
Genetic or pharmacologic blockade of mPGES-2 attenuates renal lipotoxicity and diabetic kidney disease by targeting Rev-Erbα/FABP5 signaling.
Zhong D, Chen J, Qiao R, Song C, Hao C, Zou Y, Bai M, Su W, Yang B, Sun D, Jia Z, Sun Y
Cell reports 2024 Apr 23;43(4):114075
Cell reports 2024 Apr 23;43(4):114075
Hippo-signaling-controlled MHC class I antigen processing and presentation pathway potentiates antitumor immunity.
Peng L, Zhou L, Li H, Zhang X, Li S, Wang K, Yang M, Ma X, Zhang D, Xiang S, Duan Y, Wang T, Sun C, Wang C, Lu D, Qian M, Wang Z
Cell reports 2024 Apr 23;43(4):114003
Cell reports 2024 Apr 23;43(4):114003
Systematic optimization and evaluation of culture conditions for the construction of circulating tumor cell clusters using breast cancer cell lines.
Zou J, Chen Q, He Y, Pan Y, Zhao H, Shi J, Wei Z, Yu S, Zhao Y, Han X, Lu Y, Chen W
BMC cancer 2024 Apr 23;24(1):507
BMC cancer 2024 Apr 23;24(1):507
PCV2 Induced Endothelial Derived IL-8 Affects MoDCs Maturation Mainly via NF-κB Signaling Pathway.
Zhang M, Xu W, Yang N, Li Z, Zhou S, Liu X, Wang J, Li H
Viruses 2024 Apr 22;16(4)
Viruses 2024 Apr 22;16(4)
Caspase-1 Deficiency Modulates Adipogenesis through Atg7-Mediated Autophagy: An Inflammatory-Independent Mechanism.
Wang Y, Chen G, Xu M, Cui Y, He W, Zeng H, Zeng T, Cheng R, Li X
Biomolecules 2024 Apr 20;14(4)
Biomolecules 2024 Apr 20;14(4)
Ascorbyl palmitate ameliorates inflammatory diseases by inhibition of NLRP3 inflammasome.
Zhang L, Li G, Lin B, He H, Zhou R, Jiang W
International immunopharmacology 2024 Apr 20;131:111915
International immunopharmacology 2024 Apr 20;131:111915
The prevention effect of pulsed electromagnetic fields treatment on senile osteoporosis in vivo via improving the inflammatory bone microenvironment.
Zhou J, Jia F, Qu M, Ning P, Huang X, Tan L, Liu D, Zhong P, Wu Q
Electromagnetic biology and medicine 2024 Apr 2;43(1-2):46-60
Electromagnetic biology and medicine 2024 Apr 2;43(1-2):46-60
TRAF6-mediated ubiquitination of AKT in the nucleus is a critical event underlying the desensitization of G protein-coupled receptors.
Wu C, Hu L, Liu B, Zeng X, Ma H, Cao Y, Li H, Zhang X
Cell communication and signaling : CCS 2024 Apr 2;22(1):213
Cell communication and signaling : CCS 2024 Apr 2;22(1):213
Profiling the role of m6A effectors in the regulation of pluripotent reprogramming.
Wang W, Zhou L, Li H, Sun T, Wen X, Li W, Esteban MA, Hoffman AR, Hu JF, Cui J
Human genomics 2024 Apr 2;18(1):33
Human genomics 2024 Apr 2;18(1):33
miR-3188 inhibits hepatitis B virus transcription by targeting Bcl-2.
Wang S, Xie Y, Liu F, Wang J, Yang Y, Wang J, Wang Y, Hang X
Archives of virology 2024 Apr 2;169(5):88
Archives of virology 2024 Apr 2;169(5):88
Macrophage-derived exosomes rescue the TNF-ɑ-suppressed osteo-/cementogenic differentiation of hPDLCs.
Deng Y, Xiao J, Huang X, Cao Z
Oral diseases 2024 Apr 2;
Oral diseases 2024 Apr 2;
Dimethyl fumarate covalently modifies Cys673 of NLRP3 to exert anti-inflammatory effects.
Hu H, Cai Y, Shi Y, Zhang S, Yu X, Ma T, Liao S
iScience 2024 Apr 19;27(4):109544
iScience 2024 Apr 19;27(4):109544
TDP-43 deficiency in suprachiasmatic nucleus perturbs rhythmicity of neuroactivity in prefrontal cortex.
Zhang H, Chen C, Zhang EE, Huang X
iScience 2024 Apr 19;27(4):109522
iScience 2024 Apr 19;27(4):109522
The deubiquitinase cofactor UAF1 interacts with USP1 and plays an essential role in spermiogenesis.
Wang Z, Li T, Liu D, Li M, Liu S, Yu X, Li H, Song H, Zhao W, Liu Z, Chen X, Lu G, Chen ZJ, Huang T, Liu H
iScience 2024 Apr 19;27(4):109456
iScience 2024 Apr 19;27(4):109456
Insulin-like growth factor-1 promotes the testicular sperm production by improving germ cell survival and proliferation in high-fat diet-treated male mice.
Liu G, Liu D, Zhu M, Zhang M, Li C, Xu X, Pan F
Andrology 2024 Apr 19;
Andrology 2024 Apr 19;
Neutrophil Extracellular Traps Regulate Surgical Brain Injury by Activating the cGAS-STING Pathway.
Li B, Xu L, Wang Z, Shi Q, Cui Y, Fan W, Wu Q, Tong X, Yan H
Cellular and molecular neurobiology 2024 Apr 18;44(1):36
Cellular and molecular neurobiology 2024 Apr 18;44(1):36
Verapamil Attenuates the Severity of Tendinopathy by Mitigating Mitochondrial Dysfunction through the Activation of the Nrf2/HO-1 Pathway.
Wang Z, Dong Z, Li Y, Jiao X, Liu Y, Chang H, Gan Y
Biomedicines 2024 Apr 18;12(4)
Biomedicines 2024 Apr 18;12(4)
Resveratrol Alleviates Zearalenone-Induced Intestinal Dysfunction in Mice through the NF-κB/Nrf2/HO-1 Signalling Pathway.
Xia S, Yan C, Gu J, Yuan Y, Zou H, Liu Z, Bian J
Foods (Basel, Switzerland) 2024 Apr 17;13(8)
Foods (Basel, Switzerland) 2024 Apr 17;13(8)
KDM5C-Mediated Recruitment of BRD4 to Chromatin Regulates Enhancer Activation and BET Inhibitor Sensitivity.
Qiang Y, Fan J, Xie C, Yan L, Song X, Zhang N, Lin Y, Xiong J, Zhang W, Liu Y, Wei L, Li Y, Chen S, Liang K, Li F
Cancer research 2024 Apr 15;84(8):1252-1269
Cancer research 2024 Apr 15;84(8):1252-1269
Association of GAL-8 promoter methylation levels with coronary plaque inflammation.
Xia B, Lu Y, Liang J, Li F, Peng J, Wang J, Wan C, Ding J, Le C, Dai J, Guo B, Shen Z
International journal of cardiology 2024 Apr 15;401:131782
International journal of cardiology 2024 Apr 15;401:131782
Human umbilical cord mesenchymal stem cell-derived exosomes ameliorate renal fibrosis in diabetic nephropathy by targeting Hedgehog/SMO signaling.
Zhang K, Zheng S, Wu J, He J, Ouyang Y, Ao C, Lang R, Jiang Y, Yang Y, Xiao H, Li Y, Li M, Wang H, Li C, Wu D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23599
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23599
PRMT4 interacts with NCOA4 to inhibit ferritinophagy in cisplatin-induced acute kidney injury.
Zhou L, Deng Z, Wang Y, Zhang H, Yan S, Kanwar YS, Wang Y, Dai Y, Deng F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23584
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23584
Integrated network toxicology, molecular docking, and in vivo experiments to elucidate molecular mechanism of aflatoxin B1 hepatotoxicity.
Ge B, Yan K, Sang R, Wang W, Liu X, Yu M, Liu X, Qiu Q, Zhang X
Ecotoxicology and environmental safety 2024 Apr 15;275:116278
Ecotoxicology and environmental safety 2024 Apr 15;275:116278
Quinic acid regulated TMA/TMAO-related lipid metabolism and vascular endothelial function through gut microbiota to inhibit atherosclerotic.
Jin Q, Zhang C, Chen R, Jiang L, Li H, Wu P, Li L
Journal of translational medicine 2024 Apr 15;22(1):352
Journal of translational medicine 2024 Apr 15;22(1):352
zDHHC3-mediated S-palmitoylation of SLC9A2 regulates apoptosis in kidney clear cell carcinoma.
Zhang X, Hou J, Zhou G, Wang H, Wu Z
Journal of cancer research and clinical oncology 2024 Apr 15;150(4):194
Journal of cancer research and clinical oncology 2024 Apr 15;150(4):194
Taurine ameliorates sensorimotor function by inhibiting apoptosis and activating A2 astrocytes in mice after subarachnoid hemorrhage.
Yang C, Jiang Z, Gao X, Yang H, Su J, Weng R, Ni W, Gu Y
Amino acids 2024 Apr 14;56(1):31
Amino acids 2024 Apr 14;56(1):31
CCDC58 is a potential biomarker for diagnosis, prognosis, immunity, and genomic heterogeneity in pan-cancer.
Yang K, Ma Y, Chen W, Liu L, Yang Z, He C, Zheng N, Liu X, Cheng X, Song J, Chen Y, Qiao H, Zhang R
Scientific reports 2024 Apr 13;14(1):8575
Scientific reports 2024 Apr 13;14(1):8575
Functional analysis and validation of oncodrive gene AP3S1 in ovarian cancer through filtering of mutation data from whole-exome sequencing.
Kong D, Wu Y, Liu Q, Huang C, Wang T, Huang Z, Gao Y, Li Y, Guo H
European journal of medical research 2024 Apr 12;29(1):231
European journal of medical research 2024 Apr 12;29(1):231
Hawthorn Proanthocyanidin Extract Inhibits Colorectal Carcinoma Metastasis by Targeting the Epithelial-Mesenchymal Transition Process and Wnt/β-Catenin Signaling Pathway.
Wang Z, Sun Y, Wu M, Zhou L, Zheng Y, Ren T, Li M, Zhao W
Foods (Basel, Switzerland) 2024 Apr 12;13(8)
Foods (Basel, Switzerland) 2024 Apr 12;13(8)
Hazel Leaf Polyphenol Extract Alleviated Cisplatin-Induced Acute Kidney Injury by Reducing Ferroptosis through Inhibiting Hippo Signaling.
Sun M, Chang H, Jiang F, Zhang W, Yang Q, Wang X, Lv G, Lin H, Luo H, Lin Z, Wang Y
Molecules (Basel, Switzerland) 2024 Apr 11;29(8)
Molecules (Basel, Switzerland) 2024 Apr 11;29(8)
Unlocking the Therapeutic Potential of a Manila Clam-Derived Antioxidant Peptide: Insights into Mechanisms of Action and Cytoprotective Effects against Oxidative Stress.
Jin H, Zhao H, Shi R, Fan F, Cheng W
Foods (Basel, Switzerland) 2024 Apr 11;13(8)
Foods (Basel, Switzerland) 2024 Apr 11;13(8)
Targeting FTO induces colorectal cancer ferroptotic cell death by decreasing SLC7A11/GPX4 expression.
Qiao Y, Su M, Zhao H, Liu H, Wang C, Dai X, Liu L, Liu G, Sun H, Sun M, Wang J, Li Z, Fan J, Zhang Q, Li C, Situ F, Xue J, Jia Z, Zhang C, Zhang S, Shan C
Journal of experimental & clinical cancer research : CR 2024 Apr 10;43(1):108
Journal of experimental & clinical cancer research : CR 2024 Apr 10;43(1):108
The W195 Residue of the Newcastle Disease Virus V Protein Is Critical for Multiple Aspects of Viral Self-Regulation through Interactions between V and Nucleoproteins.
Wei Q, Wang W, Meng F, Wang Y, Wei N, Tian J, Li H, Hao Q, Zhou Z, Liu H, Yang Z, Xiao S
Viruses 2024 Apr 10;16(4)
Viruses 2024 Apr 10;16(4)
Protective Effects of Isoliquiritigenin and Licochalcone B on the Immunotoxicity of BDE-47: Antioxidant Effects Based on the Activation of the Nrf2 Pathway and Inhibition of the NF-κB Pathway.
Dong M, Yang Z, Gao Q, Deng Q, Li L, Chen H
Antioxidants (Basel, Switzerland) 2024 Apr 10;13(4)
Antioxidants (Basel, Switzerland) 2024 Apr 10;13(4)
Hepatic LGR4 aggravates cholestasis-induced liver injury in mice.
Gao Y, Zhai W, Sun L, Du X, Wang X, Mulholland MW, Yin Y, Zhang W
American journal of physiology. Gastrointestinal and liver physiology 2024 Apr 1;326(4):G460-G472
American journal of physiology. Gastrointestinal and liver physiology 2024 Apr 1;326(4):G460-G472
Rutin mitigates fluoride-induced nephrotoxicity by inhibiting ROS-mediated lysosomal membrane permeabilization and the GSDME-HMGB1 axis involved in pyroptosis and inflammation.
Ma Y, Xu P, Xing H, Zhang Y, Li T, Ding X, Liu L, Niu Q
Ecotoxicology and environmental safety 2024 Apr 1;274:116195
Ecotoxicology and environmental safety 2024 Apr 1;274:116195
Mechanically tough, adhesive, self-healing hydrogel promotes annulus fibrosus repair via autologous cell recruitment and microenvironment regulation.
Wei Z, Ye H, Li Y, Li X, Liu Y, Chen Y, Yu J, Wang J, Ye X
Acta biomaterialia 2024 Apr 1;178:50-67
Acta biomaterialia 2024 Apr 1;178:50-67
Caged xanthone derivatives to promote mitochondria-mediated apoptosis in breast cancer cells.
Wang Y, Zheng H, Jiang X, Wu H, Ren Y, Xi Z, Zheng C, Xu H
Bioorganic & medicinal chemistry 2024 Apr 1;103:117655
Bioorganic & medicinal chemistry 2024 Apr 1;103:117655
MiR-181c-5p ameliorates learning and memory in sleep-deprived mice via HMGB1/TLR4/NF-κB pathway.
Hu Y, Hu C, Yin J, Zhong J, Deng Y, Yang G
Anais da Academia Brasileira de Ciencias 2023;95(suppl 1):e20220750
Anais da Academia Brasileira de Ciencias 2023;95(suppl 1):e20220750
The Involvement of PGRMC1 Signaling in Cognitive Impairment Induced by Long-Term Clozapine Treatment in Rats.
Cao T, Wang L, Jiao S, Chen H, Lin C, Zhang B, Cai H
Neuropsychobiology 2023;82(6):346-358
Neuropsychobiology 2023;82(6):346-358
Semisynthesis and in Vitro Anti-cancer Effect of New Magnolol Derivatives on the Cell Proliferation, Apoptosis, Migration, and Invasion of Human Hepatocellular Carcinoma SMMC-7721 Cells.
He NN, Wang JA, Huang D, Sun XL, Ding F, Zhao L, Zhang YX, Li HM, Wu CZ
Chemical & pharmaceutical bulletin 2023;71(11):798-803
Chemical & pharmaceutical bulletin 2023;71(11):798-803
NRF1 Alleviated Oxidative Stress of Glioblastoma Cells by Regulating NOR1.
Wang J, Chen S, Xiang W, Zhu Q, Ren N
Folia biologica 2023;69(1):13-21
Folia biologica 2023;69(1):13-21
FNDC5 Attenuates Atherosclerotic Plaque Formation and Regulates PPARα/HO-1 in ApoE-/- Mice.
Zhou B, Wang X, Wang Y, Liu D
Journal of vascular research 2023;60(3):172-182
Journal of vascular research 2023;60(3):172-182
CDKs Functional Analysis in Low Proliferating Early-Stage Pancreatic Ductal Adenocarcinoma.
Zhu S, Yang H, Liu L, Jiang Z, Ji J, Wang X, Zhong L, Liu F, Gao X, Wang H, Zhou Y
Journal of bioinformatics and systems biology : Open access 2023;6(3):187-200
Journal of bioinformatics and systems biology : Open access 2023;6(3):187-200
Phenolic profile, antioxidation and anti-proliferation activity of phenolic-rich extracts from Sanghuangporusvaninii.
Gao H, Yin C, Li C, Li Y, Shi D, Fan X, Yao F, Wu W, Li J
Current research in food science 2023;6:100519
Current research in food science 2023;6:100519
Baicalin Ameliorates Lung Injury in Rats by Inhibiting NLRP3 Inflammasome Activation via NF-[Formula: see text]B Signaling Pathway.
Yang X, Han J, Huan Z, Xu C, Wang Q, Ge X
The American journal of Chinese medicine 2023;51(4):979-996
The American journal of Chinese medicine 2023;51(4):979-996
Amelioration of Lung Fibrosis by Total Flavonoids of Astragalus via Inflammatory Modulation and Epithelium Regeneration.
Yang CG, Mao XL, Wu JF, An X, Cao JJ, Zhang XY, Li M, Zhang FF
The American journal of Chinese medicine 2023;51(2):373-389
The American journal of Chinese medicine 2023;51(2):373-389
Baicalin Reduces Immune Cell Infiltration by Inhibiting Inflammation and Protecting Tight Junctions in Ischemic Stroke Injury.
Hao Z, Zhang Z, Zhao Y, Wang D
The American journal of Chinese medicine 2023;51(2):355-372
The American journal of Chinese medicine 2023;51(2):355-372
Propofol improves ischemia reperfusion-induced liver fibrosis by regulating lncRNA HOXA11-AS.
Luo J, Liu J, Mou Y, Luo F, Liao Q, Liao Y
The Journal of toxicological sciences 2023;48(6):345-354
The Journal of toxicological sciences 2023;48(6):345-354
Methylthioacetic acid, a derivative of aroma compounds from Cucumis melo var. conomon dose-dependently triggers differentiation and apoptosis of RCM-1 human colorectal cancer cells.
Kamimura M, Sasaki A, Otani Y, Nakamura Y, Nakamura T, Kuramochi K, Imai T, Kubo N, Okamoto S
The Journal of toxicological sciences 2023;48(1):25-35
The Journal of toxicological sciences 2023;48(1):25-35
ESE-1 mediates lipopolysaccharide-induced BV2 cell inflammation via upregulation of HMGB1 expression.
Lu Y, Ding J, Huang J, Zhao Y
Journal of biosciences 2023;48
Journal of biosciences 2023;48
Ponicidin Induces Apoptosis of Murine Melanoma by Inhibiting the NF-κB Signaling Pathway.
Wang L, Lou X, Wang D, Lu K, Zhang S, Cheng B
Biological & pharmaceutical bulletin 2023;46(6):803-810
Biological & pharmaceutical bulletin 2023;46(6):803-810
C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways.
Chen Y, Liu Y, Li H, Huna R, Tan X, Li N, Zhang Y, Jiao X, Liu M
Journal of applied oral science : revista FOB 2023;31:e20220404
Journal of applied oral science : revista FOB 2023;31:e20220404
Exploring the Targets and Molecular Mechanisms of Thalidomide in the Treatment of Ulcerative Colitis: Network Pharmacology and Experimental Validation.
Li J, Tao Q, Xie Y, Wang P, Jin R, Huang X, Chen Y, Zeng C
Current pharmaceutical design 2023;29(34):2721-2737
Current pharmaceutical design 2023;29(34):2721-2737
Lycium barbarum Polysaccharides Regulating miR-181/Bcl-2 Decreased Autophagy of Retinal Pigment Epithelium with Oxidative Stress.
Yang YJ, Wang Y, Deng Y, Liu XQ, Lu J, Peng J, Li J, Zhou YS, Zhu HA, Li B, Qin YH, Peng QH
Oxidative medicine and cellular longevity 2023;2023:9554457
Oxidative medicine and cellular longevity 2023;2023:9554457
STK24 Promotes Progression of LUAD and Modulates the Immune Microenvironment.
Li Y, Liu Y, Wang K, Xue D, Huang Y, Tan Z, Chen Y
Mediators of inflammation 2023;2023:8646088
Mediators of inflammation 2023;2023:8646088
Pterostilbene Confers Protection against Diquat-Induced Intestinal Damage with Potential Regulation of Redox Status and Ferroptosis in Broiler Chickens.
Chen Y, Zhang H, Li Y, Wang T
Oxidative medicine and cellular longevity 2023;2023:8258354
Oxidative medicine and cellular longevity 2023;2023:8258354
Exploring the Effect of Compound Glycyrrhizin and Silybinin on the Metabolism of Pexidartinib in Rats Based on CYP3A4 and CYP2C9.
Su Y, Wei X, Cheng Q, Qi H, Chen J, Qiu XJ
Advances in pharmacological and pharmaceutical sciences 2023;2023:6737062
Advances in pharmacological and pharmaceutical sciences 2023;2023:6737062
JFD, a Novel Natural Inhibitor of Keap1 Alkylation, Suppresses Intracellular Mycobacterium Tuberculosis Growth through Keap1/Nrf2/SOD2-Mediated ROS Accumulation.
Wan H, Cai Y, Xiao L, Ling Y, Ge L, Mo S, Xie Q, Peng S, Zhou B, Zeng X, Chen X
Oxidative medicine and cellular longevity 2023;2023:6726654
Oxidative medicine and cellular longevity 2023;2023:6726654
Xuanhuang Runtong Tablets Relieve Slow Transit Constipation in Mice by Regulating TLR5/IL-17A Signaling Mediated by Gut Microbes.
Liang X, Wan D, Cai Y, Yue W, Wang X, Zhou H, Zhou R, Du Q, Xiao J, Zhang S
Evidence-based complementary and alternative medicine : eCAM 2023;2023:6506244
Evidence-based complementary and alternative medicine : eCAM 2023;2023:6506244
Network Pharmacology-Based Identification of Key Targets of Ziyin Mingmu Pills Acting on Age-Related Macular Degeneration.
Yang Y, Wang Y, Liu X, Deng Y, Lu J, Jiang F, Nie F, Peng J, Peng Q, Qin Y
Evidence-based complementary and alternative medicine : eCAM 2023;2023:5933125
Evidence-based complementary and alternative medicine : eCAM 2023;2023:5933125
Inhibition of miR-182-5p Targets FGF9 to Alleviate Osteoarthritis.
Sun Y, Su S, Li M, Deng A
Analytical cellular pathology (Amsterdam) 2023;2023:5911546
Analytical cellular pathology (Amsterdam) 2023;2023:5911546
Human Umbilical Cord Mesenchymal Stem Cells Inhibit Pyroptosis of Renal Tubular Epithelial Cells through miR-342-3p/Caspase1 Signaling Pathway in Diabetic Nephropathy.
Zheng S, Zhang K, Zhang Y, He J, Ouyang Y, Lang R, Ao C, Jiang Y, Xiao H, Li Y, Li M, Li C, Wu D
Stem cells international 2023;2023:5584894
Stem cells international 2023;2023:5584894
Vasoprotective Effects of Hyperoside against Cerebral Ischemia/Reperfusion Injury in Rats: Activation of Large-Conductance Ca(2+)-Activated K(+) Channels.
Hong WM, Xie YW, Zhao MY, Yu TH, Wang LN, Xu WY, Gao S, Cai HB, Guo Y, Zhang F
Neural plasticity 2023;2023:5545205
Neural plasticity 2023;2023:5545205
The Interaction of Apelin and FGFR1 Ameliorated the Kidney Fibrosis through Suppression of TGFβ-Induced Endothelial-to-Mesenchymal Transition.
Gao R, Wu Y, Yang Q, Chen L, Chen J, Wang B, Liu Z, Jin J, Li J, Wu G
Oxidative medicine and cellular longevity 2023;2023:5012474
Oxidative medicine and cellular longevity 2023;2023:5012474
QiHuangYiShen Granules Modulate the Expression of LncRNA MALAT1 and Attenuate Epithelial-Mesenchymal Transition in Kidney of Diabetic Nephropathy Rats.
Yuan LS, Du H, Ren QY, Yang RL, Liu SW, Liu SY, Shi KF, Wang B, Meng XF, Li TX, Zhang N
Evidence-based complementary and alternative medicine : eCAM 2023;2023:3357281
Evidence-based complementary and alternative medicine : eCAM 2023;2023:3357281
Calpain-2 Facilitates Autophagic/Lysosomal Defects and Apoptosis in ARPE-19 Cells and Rats Induced by Exosomes from RPE Cells under NaIO(3) Stimulation.
Zhang S, Qiu Y, Feng Y, Zhang Y, Li Y, Wang B, Wei H, Chen X, Shen L, Li W, Zheng L, Zhang Y
Oxidative medicine and cellular longevity 2023;2023:3310621
Oxidative medicine and cellular longevity 2023;2023:3310621
Upregulation of NDUFAF2 in Lung Adenocarcinoma Is a Novel Independent Prognostic Biomarker.
Zou K, Gao P, Xu X, Zhang W, Zeng Z
Computational and mathematical methods in medicine 2023;2023:2912968
Computational and mathematical methods in medicine 2023;2023:2912968
Microbiota from Exercise Mice Counteracts High-Fat High-Cholesterol Diet-Induced Cognitive Impairment in C57BL/6 Mice.
Li R, Liu R, Chen L, Wang G, Qin L, Yu Z, Wan Z
Oxidative medicine and cellular longevity 2023;2023:2766250
Oxidative medicine and cellular longevity 2023;2023:2766250
Characterization of TIM-3 Expression and Its Correlation with TNF-α and IFN-γ in Patients with Surgically Resected Lung Adenocarcinoma.
Tan J, Shen P, Yang X, Cai W, Liao H
Disease markers 2023;2023:2352945
Disease markers 2023;2023:2352945
Prevention of Bleomycin-Induced Pulmonary Inflammation and Fibrosis in Mice by Bilobalide.
Zhang X, Zhang W, Chen X, Cai Y
Evidence-based complementary and alternative medicine : eCAM 2023;2023:1973163
Evidence-based complementary and alternative medicine : eCAM 2023;2023:1973163
Leonurine Regulates Hippocampal Nerve Regeneration in Rats with Chronic and Unpredictable Mild Stress by Activating SHH/GLI Signaling Pathway and Restoring Gut Microbiota and Microbial Metabolic Homeostasis.
Meng P, Zhang X, Li D, Yang H, Lin X, Zhao H, Li P, Wang Y, Wang X, Ge J
Neural plasticity 2023;2023:1455634
Neural plasticity 2023;2023:1455634
Traxoprodil Produces Antidepressant-Like Behaviors in Chronic Unpredictable Mild Stress Mice through BDNF/ERK/CREB and AKT/FOXO/Bim Signaling Pathway.
Wang Y, Liang Z, Song W, Qin Y, Todd N, Gao M
Oxidative medicine and cellular longevity 2023;2023:1131422
Oxidative medicine and cellular longevity 2023;2023:1131422
Anomanolide C suppresses tumor progression and metastasis by ubiquitinating GPX4-driven autophagy-dependent ferroptosis in triple negative breast cancer.
Chen YM, Xu W, Liu Y, Zhang JH, Yang YY, Wang ZW, Sun DJ, Li H, Liu B, Chen LX
International journal of biological sciences 2023;19(8):2531-2550
International journal of biological sciences 2023;19(8):2531-2550
Berberine inhibits high fat diet-associated colorectal cancer through modulation of the gut microbiota-mediated lysophosphatidylcholine.
Chen H, Ye C, Wu C, Zhang J, Xu L, Wang X, Xu C, Zhang J, Guo Y, Yao Q
International journal of biological sciences 2023;19(7):2097-2113
International journal of biological sciences 2023;19(7):2097-2113
NLRP3 Inflammasome Mediates Silica-induced Lung Epithelial Injury and Aberrant Regeneration in Lung Stem/Progenitor Cell-derived Organotypic Models.
Zhou H, Zhang Q, Huang W, Zhou S, Wang Y, Zeng X, Wang H, Xie W, Kong H
International journal of biological sciences 2023;19(6):1875-1893
International journal of biological sciences 2023;19(6):1875-1893
M6A-modified circRBM33 promotes prostate cancer progression via PDHA1-mediated mitochondrial respiration regulation and presents a potential target for ARSI therapy.
Zhong C, Long Z, Yang T, Wang S, Zhong W, Hu F, Teoh JY, Lu J, Mao X
International journal of biological sciences 2023;19(5):1543-1563
International journal of biological sciences 2023;19(5):1543-1563
Development and anticancer properties of Up284, a spirocyclic candidate ADRM1/RPN13 inhibitor.
Anchoori RK, Anchoori V, Lam B, Tseng SH, Das S, Velasquez FC, Karanam B, Poddatoori D, Patnam R, Rudek MA, Chang YN, Roden RBS
PloS one 2023;18(6):e0285221
PloS one 2023;18(6):e0285221
Combinatorial expression of ebony and tan generates body color variation from nymph through adult stages in the cricket, Gryllus bimaculatus.
Inoue S, Watanabe T, Hamaguchi T, Ishimaru Y, Miyawaki K, Nikawa T, Takahashi A, Noji S, Mito T
PloS one 2023;18(5):e0285934
PloS one 2023;18(5):e0285934
Mitochondrial decline in the ageing old world primate retina: Little evidence for difference between the centre and periphery.
Kam JH, Shinhmar H, Powner MB, Hayes MJ, Aboelnour A, Jeffery G
PloS one 2023;18(5):e0273882
PloS one 2023;18(5):e0273882
Downregulation of KIAA1199 alleviated the activation, proliferation, and migration of hepatic stellate cells by the inhibition of epithelial-mesenchymal transition.
Liu J, Xia S, Han P, Zhang M, Wu J, Liao J
Open medicine (Warsaw, Poland) 2023;18(1):20230689
Open medicine (Warsaw, Poland) 2023;18(1):20230689
Identification and Characterization of a Novel Nanobody Against Human CTGF to Reveal Its Antifibrotic Effect in an in vitro Model of Liver Fibrosis.
Liu R, Zhu M, Chen J, Gai J, Huang J, Zhou Y, Wan Y, Tu C
International journal of nanomedicine 2023;18:5407-5422
International journal of nanomedicine 2023;18:5407-5422
Glycosylation-Engineered Platelet Membrane-Coated Interleukin 10 Nanoparticles for Targeted Inhibition of Vascular Restenosis.
Li F, Rong Z, Chen T, Wang P, Di X, Ni L, Liu C
International journal of nanomedicine 2023;18:5011-5030
International journal of nanomedicine 2023;18:5011-5030
Integrated Network Pharmacology, Molecular Docking and Animal Experiment to Explore the Efficacy and Potential Mechanism of Baiyu Decoction Against Ulcerative Colitis by Enema.
Cui Y, Hu J, Li Y, Au R, Fang Y, Cheng C, Xu F, Li W, Wu Y, Zhu L, Shen H
Drug design, development and therapy 2023;17:3453-3472
Drug design, development and therapy 2023;17:3453-3472
Jiawei Danxuan Koukang Alleviates Arecoline Induced Oral Mucosal Lesions: Network Pharmacology and the Combined Ultra-High Performance Liquid Chromatography (UPLC) and Mass Spectrometry (MS).
Zhou L, Tan J, Dai Y, Zhu K, Xiao Y, Wu D, Wang Z, Tan Y, Qin Y
Drug design, development and therapy 2023;17:3085-3101
Drug design, development and therapy 2023;17:3085-3101
10-Gingerol Enhances the Effect of Taxol in Triple-Negative Breast Cancer via Targeting ADRB2 Signaling.
Liang Y, Wu G, Luo T, Xie H, Zuo Q, Huang P, Li H, Chen L, Lu H, Chen Q
Drug design, development and therapy 2023;17:129-142
Drug design, development and therapy 2023;17:129-142
K(+)/Cl(-) cotransporter 2 (KCC2) and Na(+)/HCO3- cotransporter 1 (NBCe1) interaction modulates profile of KCC2 phosphorylation.
Pethe A, Hamze M, Giannaki M, Heimrich B, Medina I, Hartmann AM, Roussa E
Frontiers in cellular neuroscience 2023;17:1253424
Frontiers in cellular neuroscience 2023;17:1253424
EFEMP1 is a potential biomarker of choroid thickness change in myopia.
Shi WQ, Wan T, Li B, Li T, Zhou XD
Frontiers in neuroscience 2023;17:1144421
Frontiers in neuroscience 2023;17:1144421
Network pharmacology reveals that Berberine may function against Alzheimer's disease via the AKT signaling pathway.
Wei W, Yao JX, Zhang TT, Wen JY, Zhang Z, Luo YM, Cao Y, Li H
Frontiers in neuroscience 2023;17:1059496
Frontiers in neuroscience 2023;17:1059496
Semaphorin4F is a potential biomarker for clinical progression and prognosis in gastric cancer.
Wang H, Ji X, Chen L, Ju L, Ma Q, Wu Y, Cai W
International journal of clinical and experimental pathology 2023;16(9):210-224
International journal of clinical and experimental pathology 2023;16(9):210-224
Establishment of Risk Model and Analysis of Immunoinfiltration Based on Mitophagy-Related Associated Genes in Atrial Fibrillation.
Sang W, Wang L, Yan X, Sun H, Han Y, Wang F, Tang B, Li Y
Journal of inflammation research 2023;16:2561-2583
Journal of inflammation research 2023;16:2561-2583
Comprehensive Analysis of NABP2 as a Prognostic Biomarker and Its Correlation with Immune Infiltration in Hepatocellular Carcinoma.
Li B, Liu J, Xu L, Xu Q, Liu Z, Liu T
Journal of inflammation research 2023;16:1783-1804
Journal of inflammation research 2023;16:1783-1804
Integrated proteomics and metabolomics analysis of D-pinitol function during hippocampal damage in streptozocin-induced aging-accelerated mice.
Li X, Gao Y, Li B, Zhao W, Cai Q, Yin W, Zeng S, Li X, Gao H, Cheng M
Frontiers in molecular neuroscience 2023;16:1251513
Frontiers in molecular neuroscience 2023;16:1251513
Sex Differences in Genomic Features of Hepatitis B-Associated Hepatocellular Carcinoma With Distinct Antitumor Immunity.
Xu C, Cheng S, Chen K, Song Q, Liu C, Fan C, Zhang R, Zhu Q, Wu Z, Wang Y, Fan J, Zheng H, Lu L, Chen T, Zhao H, Jiao Y, Qu C
Cellular and molecular gastroenterology and hepatology 2023;15(2):327-354
Cellular and molecular gastroenterology and hepatology 2023;15(2):327-354
HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.
Yuan J, Lv T, Yang J, Wu Z, Yan L, Yang J, Shi Y, Jiang L
Cellular and molecular gastroenterology and hepatology 2023;15(2):307-325
Cellular and molecular gastroenterology and hepatology 2023;15(2):307-325
CKIP-1 mediates P. gingivalis-suppressed osteogenic/cementogenic differentiation of periodontal ligament cells partially via p38 signaling pathway.
Huang X, Xiao J, Wang H, Peng Y, Liu H, Ma L, Wang X, Cao Z
Journal of oral microbiology 2023;15(1):2236427
Journal of oral microbiology 2023;15(1):2236427
Slc6a13 Deficiency Attenuates Pasteurella multocida Infection-Induced Inflammation via Glycine-Inflammasome Signaling.
He F, Qiu Y, Wu X, Xia Y, Yang L, Wu C, Li P, Zhang R, Fang R, Li N, Peng Y
Journal of innate immunity 2023;15(1):107-121
Journal of innate immunity 2023;15(1):107-121
PIWI-interacting RNA-17458 is oncogenic and a potential therapeutic target in cervical cancer.
Liu L, Li L, Zu W, Jing J, Liu G, Sun T, Xie Q
Journal of Cancer 2023;14(9):1648-1659
Journal of Cancer 2023;14(9):1648-1659
A Positive Feedback Loop of E2F4-Mediated Activation of MNX1 Regulates Tumour Progression in Colorectal Cancer.
Li JK, Liu H, Zhang HW, Li J, Liang ZT
Journal of Cancer 2023;14(14):2739-2750
Journal of Cancer 2023;14(14):2739-2750
ALDOB plays a tumor-suppressive role by inhibiting AKT activation in gastric cancer.
Peng C, Yang X, Li X, Ye Z, Wang J, Wu W
Journal of Cancer 2023;14(12):2255-2262
Journal of Cancer 2023;14(12):2255-2262
Up-regulation of ABCG1 is associated with methotrexate resistance in acute lymphoblastic leukemia cells.
Chen Y, Fang H, Sun H, Wu X, Xu Y, Zhou BS, Li H
Frontiers in pharmacology 2023;14:1331687
Frontiers in pharmacology 2023;14:1331687
Integration of RRBS and RNA-seq unravels the regulatory role of DNMT3A in porcine Sertoli cell proliferation.
Xu D, Yan S, Jin H, Chen C, Tang X, Wang X, Li Y, Fei F, Yang A
Frontiers in genetics 2023;14:1302351
Frontiers in genetics 2023;14:1302351
Secondary metabolites of Bacillus subtilis L2 show antiviral activity against pseudorabies virus.
Wang X, Hao G, Zhou M, Chen M, Ling H, Shang Y
Frontiers in microbiology 2023;14:1277782
Frontiers in microbiology 2023;14:1277782
Direct interaction of the molecular chaperone GRP78/BiP with the Newcastle disease virus hemagglutinin-neuraminidase protein plays a vital role in viral attachment to and infection of culture cells.
Han C, Xie Z, Lv Y, Liu D, Chen R
Frontiers in immunology 2023;14:1259237
Frontiers in immunology 2023;14:1259237
Tangeretin attenuates bleomycin-induced pulmonary fibrosis by inhibiting epithelial-mesenchymal transition via the PI3K/Akt pathway.
Li J, Wei Q, Song K, Wang Y, Yang Y, Li M, Yu J, Su G, Peng L, Fu B, Yi P
Frontiers in pharmacology 2023;14:1247800
Frontiers in pharmacology 2023;14:1247800
6-Gingerol alleviates placental injury in preeclampsia by inhibiting oxidative stress via BNIP3/LC3 signaling-mediated trophoblast mitophagy.
Li A, Zhao M, Yang Z, Fang Z, Qi W, Zhang C, Zhou M, Guo J, Li S, Wang X, Zhang M
Frontiers in pharmacology 2023;14:1243734
Frontiers in pharmacology 2023;14:1243734
Transcriptome sequencing and functional verification revealed the roles of exogenous magnesium in tobacco anti-PVY infection.
Guo H, Xu C, Wang F, Jiang L, Lei X, Zhang M, Li R, Lan X, Xia Z, Wang Z, Wu Y
Frontiers in microbiology 2023;14:1232279
Frontiers in microbiology 2023;14:1232279
Artesunate, as an Hsp90 inhibitor, inhibits the proliferation of Burkitt's lymphoma cells by inhibiting AKT and ERK.
Yuan-Ce L, Qi Z, Hong-Yang Z, Yan-Wen W, Yu-Mei S, Bi-Juan Y, Jun-Lin Y
Frontiers in pharmacology 2023;14:1218467
Frontiers in pharmacology 2023;14:1218467
Choroidal circulation disturbance is an initial factor in outer retinal degeneration in rats under simulated weightlessness.
Mu Y, Wei D, Yao L, Xu X, Li S, Cao R, Chen T, Zhang Z
Frontiers in physiology 2023;14:1198862
Frontiers in physiology 2023;14:1198862
Electroacupuncture alleviates ulcerative colitis by targeting CXCL1: evidence from the transcriptome and validation.
Zhang RB, Dong LC, Shen Y, Li HY, Huang Q, Yu SG, Wu QF
Frontiers in immunology 2023;14:1187574
Frontiers in immunology 2023;14:1187574
Cholesterol 25-hydroxylase suppresses avian reovirus replication by its enzymatic product 25-hydroxycholesterol.
Wang Y, Zuo W, Zhang Y, Bo Z, Zhang C, Zhang X, Wu Y
Frontiers in microbiology 2023;14:1178005
Frontiers in microbiology 2023;14:1178005
Acute murine cytomegalovirus infection boosts cell-type specific response and lipid metabolism changes in the liver of infant mice.
Gao J, Wang A, Bu X, Jia W
Frontiers in immunology 2023;14:1169869
Frontiers in immunology 2023;14:1169869
African swine fever virus pA104R protein acts as a suppressor of type I interferon signaling.
Chen Q, Li L, Guo S, Liu Z, Liu L, Tan C, Chen H, Wang X
Frontiers in microbiology 2023;14:1169699
Frontiers in microbiology 2023;14:1169699
Role of asparagine biosynthesis pathway in Siniperca chuatsi rhabdovirus proliferation.
Li F, Fu X, Luo X, Lin Q, Liang H, Niu Y, Liu L, Li N
Frontiers in microbiology 2023;14:1165491
Frontiers in microbiology 2023;14:1165491
Probiotics treatment ameliorated mycophenolic acid-induced colitis by enhancing intestinal barrier function and improving intestinal microbiota dysbiosis in mice.
Zhang P, Chen J, Ming Y, Niu Y
Frontiers in microbiology 2023;14:1153188
Frontiers in microbiology 2023;14:1153188
Tetrandrine inhibits the proliferation of mesangial cells induced by enzymatically deglycosylated human IgA1 via IgA receptor/MAPK/NF-κB signaling pathway.
Xu W, Song W, Chen S, Jin S, Xue X, Min J, Wang X, You P
Frontiers in pharmacology 2023;14:1150829
Frontiers in pharmacology 2023;14:1150829
Gut microbiota from sigma-1 receptor knockout mice induces depression-like behaviors and modulates the cAMP/CREB/BDNF signaling pathway.
Li JH, Liu JL, Li XW, Liu Y, Yang JZ, Chen LJ, Zhang KK, Xie XL, Wang Q
Frontiers in microbiology 2023;14:1143648
Frontiers in microbiology 2023;14:1143648
E. coli Nissle 1917 ameliorates mitochondrial injury of granulosa cells in polycystic ovary syndrome through promoting gut immune factor IL-22 via gut microbiota and microbial metabolism.
Luo M, Chen Y, Pan X, Chen H, Fan L, Wen Y
Frontiers in immunology 2023;14:1137089
Frontiers in immunology 2023;14:1137089
Apilimod activates the NLRP3 inflammasome through lysosome-mediated mitochondrial damage.
Hou Y, He H, Ma M, Zhou R
Frontiers in immunology 2023;14:1128700
Frontiers in immunology 2023;14:1128700
Identification and validation of hub genes in drug induced acute kidney injury basing on integrated transcriptomic analysis.
Deng YX, Liu K, Qiu QX, Tang ZY, Que RM, Li DK, Gu XR, Zhou GL, Wu YF, Zhou LY, Yin WJ, Zuo XC
Frontiers in immunology 2023;14:1126348
Frontiers in immunology 2023;14:1126348
Protective effects of Scutellariae Radix Carbonisata-derived carbon dots on blood-heat and hemorrhage rats.
Zhang M, Cheng J, Luo J, Li C, Hou T, Zhao Y, Wang Y, Qu H, Kong H
Frontiers in pharmacology 2023;14:1118550
Frontiers in pharmacology 2023;14:1118550
TIGAR deficiency induces caspase-1-dependent trophoblasts pyroptosis through NLRP3-ASC inflammasome.
Guo J, Zhou M, Zhao M, Li S, Fang Z, Li A, Zhang M
Frontiers in immunology 2023;14:1114620
Frontiers in immunology 2023;14:1114620
Dendrobium mixture ameliorates type 2 diabetes mellitus with non-alcoholic fatty liver disease through PPAR gamma: An integrated study of bioinformatics analysis and experimental verification.
Zhuang S, Zhang J, Lin X, Wang X, Yu W, Shi H
Frontiers in pharmacology 2023;14:1112554
Frontiers in pharmacology 2023;14:1112554
Effect of acupuncture on the opening time of implantation window and endometrial receptivity in controlled ovarian hyperstimulation rats during peri-implantation period.
Hu R, Huang Y, Song Y, Wu X, Song K, Huang G, Zhang M, Dong H
Frontiers in endocrinology 2023;14:1110266
Frontiers in endocrinology 2023;14:1110266
Dietary fiber alters immunity and intestinal barrier function of different breeds of growing pigs.
Ding S, Cheng Y, Azad MAK, Dong H, He J, Huang P, Kong X
Frontiers in immunology 2023;14:1104837
Frontiers in immunology 2023;14:1104837
The TRPM4 channel inhibitor 9-phenanthrol alleviates cerebral edema after traumatic brain injury in rats.
Ma P, Huang N, Tang J, Zhou Z, Xu J, Chen Y, Zhang M, Huang Q, Cheng Y
Frontiers in pharmacology 2023;14:1098228
Frontiers in pharmacology 2023;14:1098228
Sirtuin 1 activator alleviated lethal inflammatory injury via promotion of autophagic degradation of pyruvate kinase M2.
Zhao S, Sun Y, Wu X, Yang Y, Fan K, Hu K, Qin Y, Li K, Lin L, Chen K, Ma Y, Zhu M, Liu G, Zhang L
Frontiers in pharmacology 2023;14:1092943
Frontiers in pharmacology 2023;14:1092943
Identification of immune signatures in Parkinson's disease based on co-expression networks.
Dong X, Li Y, Li Q, Li W, Wu G
Frontiers in genetics 2023;14:1090382
Frontiers in genetics 2023;14:1090382
RUNX1/CD44 axis regulates the proliferation, migration, and immunotherapy of gliomas: A single-cell sequencing analysis.
Zhang H, Cao H, Luo H, Zhang N, Wang Z, Dai Z, Wu W, Liu G, Xie Z, Cheng Q, Cheng Y
Frontiers in immunology 2023;14:1086280
Frontiers in immunology 2023;14:1086280
Integrated analysis of Dendrobium nobile extract Dendrobin A against pancreatic ductal adenocarcinoma based on network pharmacology, bioinformatics, and validation experiments.
Xu X, Yu Y, Yang L, Wang B, Fan Y, Ruan B, Zhang X, Dai H, Mei W, Jie W, Zheng S
Frontiers in pharmacology 2023;14:1079539
Frontiers in pharmacology 2023;14:1079539
The prognostic value of the GPAT/AGPAT gene family in hepatocellular carcinoma and its role in the tumor immune microenvironment.
Wen P, Wang R, Xing Y, Ouyang W, Yuan Y, Zhang S, Liu Y, Peng Z
Frontiers in immunology 2023;14:1026669
Frontiers in immunology 2023;14:1026669
A strategy of local hydrogen capture and catalytic hydrogenation for enhanced therapy of chronic liver diseases.
Tao G, Liu F, Jin Z, Liu B, Wang H, Li D, Tang W, Chen Y, He Q, Qin S
Theranostics 2023;13(8):2455-2470
Theranostics 2023;13(8):2455-2470
Platelets promote CRC by activating the C5a/C5aR1 axis via PSGL-1/JNK/STAT1 signaling in tumor-associated macrophages.
Li X, Chen X, Gong S, Zhao J, Yao C, Zhu H, Xiao R, Qin Y, Li R, Sun N, Li X, Dong F, Zhao T, Pan Y, Yang J
Theranostics 2023;13(6):2040-2056
Theranostics 2023;13(6):2040-2056
ZY-444 inhibits the growth and metastasis of prostate cancer by targeting TNFAIP3 through TNF signaling pathway.
Han MT, Pei H, Sun QQ, Wang CL, Li P, Xie YY, Cao LJ, Zhang XX, Sun ZL
American journal of cancer research 2023;13(4):1533-1546
American journal of cancer research 2023;13(4):1533-1546
IRG1/Itaconate induces metabolic reprogramming to suppress ER-positive breast cancer cell growth.
Wang HC, Chang WC, Lee DY, Li XG, Hung MC
American journal of cancer research 2023;13(3):1067-1081
American journal of cancer research 2023;13(3):1067-1081
DNMT1 mediates the disturbed flow-induced endothelial to mesenchymal transition through disrupting β-alanine and carnosine homeostasis.
Zhao J, Zhao C, Yang F, Jiang Z, Zhu J, Yao W, Pang W, Zhou J
Theranostics 2023;13(13):4392-4411
Theranostics 2023;13(13):4392-4411
Network pharmacology and experimental verification reveal the mechanism of safranal against glioblastoma (GBM).
Yang X, Lu D, Sun Y, Wei T, Man D, Chen A, Luo T, Zhao F, Liu X, Cheng B, Wang X, Zhao P, Wang D, Li X
Frontiers in oncology 2023;13:1255164
Frontiers in oncology 2023;13:1255164
BPOZ-2 is a negative regulator of the NLPR3 inflammasome contributing to SARS-CoV-2-induced hyperinflammation.
Li J, Lin H, Fan T, Huang L, Zhang X, Tai Y, Fang Y, Li Q, Zhao R, Wang P, Zhou L, Wan L, Wu Y, Zhong H, Wei C, Yang X
Frontiers in cellular and infection microbiology 2023;13:1134511
Frontiers in cellular and infection microbiology 2023;13:1134511
Study on the protective effect of OM-MSCs on Golgi apparatus after intracerebral hemorrhage in Sprague-Dawley rats.
Liu J, Hu Z, Huang Y, Zhang Y, Peng D
American journal of stem cells 2023;12(5):124-137
American journal of stem cells 2023;12(5):124-137
Selective HDAC6 inhibitor TubA offers neuroprotection after intracerebral hemorrhage via inhibiting neuronal apoptosis.
Peng C, Gong X, Hu Z, Chen C, Jiang Z
PeerJ 2023;11:e15293
PeerJ 2023;11:e15293
Investigation of anti-diabetic effect of a novel coenzyme Q10 derivative.
Tan X, Yang X, Xu X, Peng Y, Li X, Deng Y, Zhang X, Qiu W, Wu D, Ruan Y, Zhi C
Frontiers in chemistry 2023;11:1280999
Frontiers in chemistry 2023;11:1280999
Tanshinone IIA inhibits cardiomyocyte pyroptosis through TLR4/NF-κB p65 pathway after acute myocardial infarction.
Chai R, Ye Z, Xue W, Shi S, Wei Y, Hu Y, Wu H
Frontiers in cell and developmental biology 2023;11:1252942
Frontiers in cell and developmental biology 2023;11:1252942
Evidence for developmental vascular-associated necroptosis and its contribution to venous-lymphatic endothelial differentiation.
Meng H, Zhao Y, Li Y, Fan H, Yi X, Meng X, Wang P, Fu F, Wu S, Wang Y
Frontiers in cell and developmental biology 2023;11:1229788
Frontiers in cell and developmental biology 2023;11:1229788
Role of UDP-glucose ceramide glucosyltransferase in venous malformation.
Chen S, Wang Y, Kong L, Ji Y, Cui J, Shen W
Frontiers in cell and developmental biology 2023;11:1178045
Frontiers in cell and developmental biology 2023;11:1178045
The combination of NDUFS1 with CD4(+) T cell infiltration predicts favorable prognosis in kidney renal clear cell carcinoma.
Wu D, He L, Xu Z, Tian RF, Fan XY, Fan J, Ai J, Bian HJ, Qin WJ, Qin J, Li L
Frontiers in cell and developmental biology 2023;11:1168462
Frontiers in cell and developmental biology 2023;11:1168462
Effect of blood flow-restricted resistance training on myocardial fibrosis in early spontaneously hypertensive rats.
Tan Z, Chen P, Zheng Y, Pan Y, Wang B, Zhao Y
Frontiers in cardiovascular medicine 2023;10:1101748
Frontiers in cardiovascular medicine 2023;10:1101748
Inhibition of tiRNA-Gly-GCC ameliorates neointimal formation via CBX3-mediated VSMCs phenotypic switching.
Rong Z, Li F, Zhang R, Niu S, Di X, Ni L, Liu C
Frontiers in cardiovascular medicine 2023;10:1030635
Frontiers in cardiovascular medicine 2023;10:1030635
Role of NLRP3 inflammasome activation in HCC cell progression.
Dai B, Cao H, Hu Y, Gong Z, Huang X, Chen Y, Liu F, Peng X, Zhang Y, Lei X
Heliyon 2023 Sep;9(9):e19542
Heliyon 2023 Sep;9(9):e19542
Electroacupuncture preconditioning protects against myocardial ischemia-reperfusion injury by modulating dynamic inflammatory response.
Bai H, Xu SL, Shi JJ, Ding YP, Liu QQ, Jiang CH, He LL, Zhang HR, Lu SF, Gu YH
Heliyon 2023 Sep;9(9):e19396
Heliyon 2023 Sep;9(9):e19396
MAVI1, an endoplasmic reticulum-localized microprotein, suppresses antiviral innate immune response by targeting MAVS on mitochondrion.
Shi TT, Huang Y, Li Y, Dai XL, He YH, Ding JC, Ran T, Shi Y, Yuan Q, Li WJ, Liu W
Science advances 2023 Sep;9(35):eadg7053
Science advances 2023 Sep;9(35):eadg7053
WBP2 restrains the lysosomal degradation of GPX4 to inhibit ferroptosis in cisplatin-induced acute kidney injury.
Deng Z, Wang Y, Liu J, Zhang H, Zhou L, Zhao H, Han Y, Yan S, Dong Z, Wang Y, Dai Y, Deng F
Redox biology 2023 Sep;65:102826
Redox biology 2023 Sep;65:102826
Transcription Factor BCL11A Regulates Schwann Cell Behavior During Peripheral Nerve Regeneration.
Zhang Y, Shen Y, Zhao L, Zhao Q, Zhao L, Yi S
Molecular neurobiology 2023 Sep;60(9):5352-5365
Molecular neurobiology 2023 Sep;60(9):5352-5365
Moderate Intensity of Treadmill Exercise Rescues TBI-Induced Ferroptosis, Neurodegeneration, and Cognitive Impairments via Suppressing STING Pathway.
Chen J, Zhu T, Yu D, Yan B, Zhang Y, Jin J, Yang Z, Zhang B, Hao X, Chen Z, Yan C, Yu J
Molecular neurobiology 2023 Sep;60(9):4872-4896
Molecular neurobiology 2023 Sep;60(9):4872-4896
TRIM9 promotes Müller cell-derived retinal stem cells to differentiate into retinal ganglion cells by regulating Atoh7.
Zeng Q, Zhou J, Hua X
In vitro cellular & developmental biology. Animal 2023 Sep;59(8):586-595
In vitro cellular & developmental biology. Animal 2023 Sep;59(8):586-595
Isoquercitrin Played a Neuroprotective Role in Rats After Cerebral Ischemia/Reperfusion Through Up-Regulating Neuroglobin and Anti-Oxidative Stress.
Li X, Yi L, Liu X, Chen X, Chen S, Cai S
Transplantation proceedings 2023 Sep;55(7):1751-1761
Transplantation proceedings 2023 Sep;55(7):1751-1761
Hypoxia caused by unilateral nasal obstruction decreases mandibular density in rats through inhibition of Cyp1a1 expression.
Xu Y, Wang Y, Xiao H, Li Y
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2023 Sep;52(8):786-794
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2023 Sep;52(8):786-794
Sophoricoside attenuates autoimmune‑mediated liver injury through the regulation of oxidative stress and the NF‑κB signaling pathway.
Chen Y, Lei Y, Wang H, Wang L, Xu J, Wang S, Yu M, Peng Z, Xiao F, Tian D, Liu M
International journal of molecular medicine 2023 Sep;52(3)
International journal of molecular medicine 2023 Sep;52(3)
FBXO28 suppresses liver cancer invasion and metastasis by promoting PKA-dependent SNAI2 degradation.
Qiao X, Lin J, Shen J, Chen Y, Zheng L, Ren H, Zhao X, Yang H, Li P, Wang Z
Oncogene 2023 Sep;42(39):2878-2891
Oncogene 2023 Sep;42(39):2878-2891
Klotho-beta attenuates Rab8a-mediated exosome regulation and promotes prostate cancer progression.
Wu T, Zhang Y, Han Q, Lu X, Cheng Y, Chen J, Sha J, Xia W
Oncogene 2023 Sep;42(38):2801-2815
Oncogene 2023 Sep;42(38):2801-2815
The Circadian System Is Essential for the Crosstalk of VEGF-Notch-mediated Endothelial Angiogenesis in Ischemic Stroke.
Zhang Y, Zhao X, Guo C, Zhang Y, Zeng F, Yin Q, Li Z, Shao L, Zhou D, Liu L
Neuroscience bulletin 2023 Sep;39(9):1375-1395
Neuroscience bulletin 2023 Sep;39(9):1375-1395
Cuproptosis enhances docetaxel chemosensitivity by inhibiting autophagy via the DLAT/mTOR pathway in prostate cancer.
Wen H, Qu C, Wang Z, Gao H, Liu W, Wang H, Sun H, Gu J, Yang Z, Wang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Sep;37(9):e23145
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Sep;37(9):e23145
Pinocembrin alleviates pyroptosis and apoptosis through ROS elimination in random skin flaps via activation of SIRT3.
Li J, Li Y, Wang X, Xie Y, Lou J, Yang Y, Jiang S, Ye M, Chen H, Diao W, Xu S
Phytotherapy research : PTR 2023 Sep;37(9):4059-4075
Phytotherapy research : PTR 2023 Sep;37(9):4059-4075
Isoamericanin A improves lipopolysaccharide-induced memory impairment in mice through suppression of the nicotinamide adenine dinucleotide phosphateoxidase-dependent nuclear factor kappa B signaling pathway.
Yang Y, Chen R, Che Y, Yao X, Fang M, Wang Y, Zhou D, Li N, Hou Y
Phytotherapy research : PTR 2023 Sep;37(9):3982-4001
Phytotherapy research : PTR 2023 Sep;37(9):3982-4001
LINC00938 alleviates hypoxia ischemia encephalopathy induced neonatal brain injury by regulating oxidative stress and inhibiting JNK/p38 MAPK signaling pathway.
Zhao J, Le M, Li J, Huang Q, Chen H, Zhang W, Mao H, Sun Q, Li A, Zhao Y, Yu L, Yi M, Wang J, Li X, Zhang G, Ma J, Dong X
Experimental neurology 2023 Sep;367:114449
Experimental neurology 2023 Sep;367:114449
Silibinin ameliorates deoxycholic acid-induced pyroptosis in steatotic HepG2 cells by inhibiting NLRP3 inflammasome activation.
Mai M, Wang Y, Luo M, Li Z, Wang D, Ruan Y, Guo H
Biochemistry and biophysics reports 2023 Sep;35:101545
Biochemistry and biophysics reports 2023 Sep;35:101545
CHAF1A promotes the proliferation and growth of epithelial ovarian cancer cells by affecting the phosphorylation of JAK2/STAT3 signaling pathway.
Xia D, Xu X, Wei J, Wang W, Xiong J, Tan Q, Xue P, Wang H
Biochemistry and biophysics reports 2023 Sep;35:101522
Biochemistry and biophysics reports 2023 Sep;35:101522
Lysine methylation of PPP1CA by the methyltransferase SUV39H2 disrupts TFEB-dependent autophagy and promotes intervertebral disc degeneration.
Liang H, Luo R, Li G, Zhang W, Zhu D, Wu D, Zhou X, Tong B, Wang B, Feng X, Wang K, Song Y, Yang C
Cell death and differentiation 2023 Sep;30(9):2135-2150
Cell death and differentiation 2023 Sep;30(9):2135-2150
Porcine reproductive and respiratory syndrome virus-mediated lactate facilitates virus replication by targeting MAVS.
Zhang L, Liu X, Mao J, Sun Y, Gao Y, Bai J, Jiang P
Veterinary microbiology 2023 Sep;284:109846
Veterinary microbiology 2023 Sep;284:109846
PEDV N protein capture protein translation element PABPC1 and eIF4F to promote viral replication.
Zhai H, Qin W, Dong S, Yang X, Zhai X, Tong W, Liu C, Zheng H, Yu H, Kong N, Tong G, Shan T
Veterinary microbiology 2023 Sep;284:109844
Veterinary microbiology 2023 Sep;284:109844
PRRSV inhibited the proliferation of CSFV by inducing IL-1β maturation via NLRP3 inflammasome activation.
Chen D, Tuo T, Zhang Y, Zhou L, Ge X, Han J, Guo X, Yang H
Veterinary microbiology 2023 Sep;284:109825
Veterinary microbiology 2023 Sep;284:109825
Tetracaine hydrochloride induces macrophage pyroptosis through caspase‑1/11‑GSDMD signaling pathways.
Zhang R, Gou W, Yi P, Qin Z, Zhu D, Jia J, Liu L, Jiang X, Feng J
Experimental and therapeutic medicine 2023 Sep;26(3):428
Experimental and therapeutic medicine 2023 Sep;26(3):428
Antisense lncRNA-RP11-498C9.13 promotes bladder cancer progression by enhancing reactive oxygen species-induced mitophagy.
Song W, Li Z, Yang K, Gao Z, Zhou Q, Li P
The journal of gene medicine 2023 Sep;25(9):e3527
The journal of gene medicine 2023 Sep;25(9):e3527
Knockdown of AK142426 suppresses M2 macrophage polarization and inflammation in peritoneal fibrosis via binding to c-Jun.
Shao Q, Jiang C, Zhang Q, Liu J, Jin B, Zhao M, Xia Y
The journal of gene medicine 2023 Sep;25(9):e3524
The journal of gene medicine 2023 Sep;25(9):e3524
Whether the Subacute MPTP-Treated Mouse is as Suitable as a Classic Model of Parkinsonism.
Qi Y, Zhang Z, Li Y, Zhao G, Huang J, Zhang Y, Xue J, Tang X
Neuromolecular medicine 2023 Sep;25(3):360-374
Neuromolecular medicine 2023 Sep;25(3):360-374
Glutaredoxin 2 protects lens epithelial cells from epithelial-mesenchymal transition by suppressing mitochondrial oxidative stress-related upregulation of integrin-linked kinase.
Chen X, Chen Y, Li C, Li J, Zhang S, Liang C, Deng Q, Guo Z, Guo C, Yan H
Experimental eye research 2023 Sep;234:109609
Experimental eye research 2023 Sep;234:109609
The long noncoding RNA CIRBIL is a regulator of steroidogenesis in mice.
Huang X, Liu X, Zhang X, Yang Y, Gao H, Gao J, Bao H, Zhao L, Yang G, Zhang Y, Liu D
Reproductive biology 2023 Sep;23(3):100783
Reproductive biology 2023 Sep;23(3):100783
EIF4A3-regulated hsa_circ_0001445 can inhibit the progression of laryngeal squamous cell carcinoma via hsa-miR-432-5p-dependent up-regulation of RGMA expression.
Yu M, Cao H, Yang J, Liu T, Gao J, Wang B
Cell cycle (Georgetown, Tex.) 2023 Sep;22(18):2038-2056
Cell cycle (Georgetown, Tex.) 2023 Sep;22(18):2038-2056
Hypoxia-induced GPCPD1 depalmitoylation triggers mitophagy via regulating PRKN-mediated ubiquitination of VDAC1.
Liu Y, Zhang H, Liu Y, Zhang S, Su P, Wang L, Li Y, Liang Y, Wang X, Zhao W, Chen B, Luo D, Zhang N, Yang Q
Autophagy 2023 Sep;19(9):2443-2463
Autophagy 2023 Sep;19(9):2443-2463
Heat shock factor 1 promotes neurite outgrowth and suppresses inflammation in the severed spinal cord of geckos.
He BQ, Li AC, Hou YX, Li H, Zhang XY, Hao HF, Song HH, Cai RX, Wang YJ, Zhou Y, Wang YJ
Neural regeneration research 2023 Sep;18(9):2011-2018
Neural regeneration research 2023 Sep;18(9):2011-2018
TRAF6-TAK1-IKKβ pathway mediates TLR2 agonists activating "one-step" NLRP3 inflammasome in human monocytes.
Chen M, Yu S, Gao Y, Li J, Wang X, Wei B, Meng G
Cytokine 2023 Sep;169:156302
Cytokine 2023 Sep;169:156302
The 5-HT(7) receptors in the VLO contribute to the development of morphine-induced behavioral sensitization in rats.
Yang JS, Gao FF, Yang XX, Liang F, Yang ZJ, Chen J, Zhang YX, Yan CX
Neurochemistry international 2023 Sep;168:105566
Neurochemistry international 2023 Sep;168:105566
Analysis of gene expression profiles and experimental validations of a rat chronic cervical cord compression model.
Pu PM, Li ZY, Dai YX, Sun YL, Wang YJ, Cui XJ, Yao M
Neurochemistry international 2023 Sep;168:105564
Neurochemistry international 2023 Sep;168:105564
The mechanism of metformin combined with total flavonoids of Rhizoma Drynariae on ovariectomy-induced osteoporotic rats.
Jiang N, Jin H, Yang K, Zhang Z, Xu W, Chen X, Zhang Z, Xu H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115181
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115181
PFKFB2 is a favorable prognostic biomarker for colorectal cancer by suppressing metastasis and tumor glycolysis.
Liu F, Wei X, Chen Z, Chen Y, Hu P, Jin Y
Journal of cancer research and clinical oncology 2023 Sep;149(12):10737-10752
Journal of cancer research and clinical oncology 2023 Sep;149(12):10737-10752
USP2 promotes cell proliferation and metastasis in choroidal melanoma via stabilizing Snail.
Wei C, Zhao X, Zhang H, Wang L
Journal of cancer research and clinical oncology 2023 Sep;149(11):9263-9276
Journal of cancer research and clinical oncology 2023 Sep;149(11):9263-9276
In vitro and in vivo study on the treatment of non-small cell lung cancer with radionuclide labeled PD-L1 nanobody.
Zhu M, Zhang J, Yang M, Zhang H, Xu T, Kan F, Zhang X, Zhang S, Yin Y, Yu F
Journal of cancer research and clinical oncology 2023 Sep;149(11):8429-8442
Journal of cancer research and clinical oncology 2023 Sep;149(11):8429-8442
The kinase inhibitory region of SOCS3 attenuates reactive astrogliosis and astroglial scar in mice after traumatic brain injury.
Cai Z, Zhang Z, Zhang L, Tan R, Wang Y, Sun M, Hu X, Ge Q, An J, Lu H
Journal of chemical neuroanatomy 2023 Sep;131:102273
Journal of chemical neuroanatomy 2023 Sep;131:102273
IGF2BP3 mediates the mRNA degradation of NF1 to promote triple-negative breast cancer progression via an m6A-dependent manner.
Zhang X, Shi L, Sun HD, Wang ZW, Xu F, Wei JF, Ding Q
Clinical and translational medicine 2023 Sep;13(9):e1427
Clinical and translational medicine 2023 Sep;13(9):e1427
Circular RNA circARPC1B functions as a stabilisation enhancer of Vimentin to prevent high cholesterol-induced articular cartilage degeneration.
Li J, Li X, Zhou S, Wang Y, Ying T, Wang Q, Wu Y, Zhao F
Clinical and translational medicine 2023 Sep;13(9):e1415
Clinical and translational medicine 2023 Sep;13(9):e1415
ACSL4 promotes ferroptosis and M1 macrophage polarization to regulate the tumorigenesis of nasopharyngeal carcinoma.
Chen P, Wang D, Xiao T, Gu W, Yang H, Yang M, Wang H
International immunopharmacology 2023 Sep;122:110629
International immunopharmacology 2023 Sep;122:110629
Pharmacological activation of the Nrf2 pathway by Taxifolin remodels articular cartilage microenvironment for the therapy of Osteoarthritis.
Jiang H, Yu J, Yan Z, Lin Z, Lin M, Mao Y, Hong Z, Lin J, Xue X, Pan X
International immunopharmacology 2023 Sep;122:110587
International immunopharmacology 2023 Sep;122:110587
CD73 inhibits titanium particle-associated aseptic loosening by alternating activation of macrophages.
Sun Z, Kang J, Yang S, Zhang Y, Huang N, Zhang X, Du G, Jiang J, Ning B
International immunopharmacology 2023 Sep;122:110561
International immunopharmacology 2023 Sep;122:110561
Lunasin reduces the susceptibility of IL-10 deficient mice to inflammatory bowel disease and modulates the activation of the NLRP3 inflammasome.
Nieto-Veloza A, Hong S, Reeder M, Sula MJ, D'Souza DH, Zhong Q, Dia VP
The Journal of nutritional biochemistry 2023 Sep;119:109383
The Journal of nutritional biochemistry 2023 Sep;119:109383
Comparison of endocytosis pathways of Duck Tembusu virus in BHK-21 and duck embryo fibroblasts.
Xian X, Yang S, Shi Y, Chen Q
Poultry science 2023 Sep;102(9):102891
Poultry science 2023 Sep;102(9):102891
miR-146b-5p promotes duck Tembusu virus replication by targeting RPS14.
Huang J, Lei L, Cui M, Cheng A, Wang M, Liu M, Zhu D, Chen S, Zhao X, Yang Q, Wu Y, Zhang S, Ou X, Mao S, Gao Q, Sun D, Tian B, Yin Z, Jia R
Poultry science 2023 Sep;102(9):102890
Poultry science 2023 Sep;102(9):102890
Targeted knockout of Mx in the DF-1 chicken fibroblast cell line impairs immune response against Newcastle disease virus.
Wang L, Xue Z, Wang J, Jian Y, Lu H, Ma H, Wang S, Zeng W, Zhang T
Poultry science 2023 Sep;102(9):102855
Poultry science 2023 Sep;102(9):102855
TP53RK Drives the Progression of Chronic Kidney Disease by Phosphorylating Birc5.
Wu M, Jin Q, Xu X, Fan J, Chen W, Miao M, Gu R, Zhang S, Guo Y, Huang S, Zhang Y, Zhang A, Jia Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(25):e2301753
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(25):e2301753
Estrogen-Induced LncRNA, LINC02568, Promotes Estrogen Receptor-Positive Breast Cancer Development and Drug Resistance Through Both In Trans and In Cis Mechanisms.
Chen X, Ding JC, Hu GS, Shu XY, Liu Y, Du J, Wen ZJ, Liu JY, Huang HH, Tang GH, Liu W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(25):e2206663
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(25):e2206663
Ochratoxin A induces abnormal tryptophan metabolism in the intestine and liver to activate AMPK signaling pathway.
Ma W, Fu Y, Zhu S, Xia D, Zhai S, Xiao D, Zhu Y, Dione M, Ben L, Yang L, Wang W
Journal of animal science and biotechnology 2023 Sep 8;14(1):125
Journal of animal science and biotechnology 2023 Sep 8;14(1):125
Gut microbes exacerbate systemic inflammation and behavior disorders in neurologic disease CADASIL.
Liu S, Men X, Guo Y, Cai W, Wu R, Gao R, Zhong W, Guo H, Ruan H, Chou S, Mai J, Ping S, Jiang C, Zhou H, Mou X, Zhao W, Lu Z
Microbiome 2023 Sep 8;11(1):202
Microbiome 2023 Sep 8;11(1):202
Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation.
Wang J, Xie W, Li N, Li W, Zhang Z, Fan N, Ouyang Z, Zhao Y, Lai C, Li H, Chen M, Quan L, Li Y, Jiang Y, Jia W, Fu L, Mazid MA, Zhu Y, Maxwell PH, Pan G, Esteban MA, Dai Z, Lai L
Cell stem cell 2023 Sep 7;30(9):1235-1245.e6
Cell stem cell 2023 Sep 7;30(9):1235-1245.e6
SUMO1-regulated DBC1 promotes p53-dependent stress-induced apoptosis of lens epithelial cells.
Wang Y, Wang JM, Xiao Y, Hu XB, Zheng SY, Fu JL, Zhang L, Gan YW, Liang XM, Li DW
Aging 2023 Sep 7;15(17):8812-8832
Aging 2023 Sep 7;15(17):8812-8832
Asarinin attenuates bleomycin-induced pulmonary fibrosis by activating PPARγ.
Zeng Q, Zhou TT, Huang WJ, Huang XT, Huang L, Zhang XH, Sang XX, Luo YY, Tian YM, Wu B, Liu L, Luo ZQ, He B, Liu W, Tang SY
Scientific reports 2023 Sep 7;13(1):14706
Scientific reports 2023 Sep 7;13(1):14706
Reduced expression of phosphorylated ataxia-telangiectasia mutated gene is related to poor prognosis and gemcitabine chemoresistance in pancreatic cancer.
Xun J, Ohtsuka H, Hirose K, Douchi D, Nakayama S, Ishida M, Miura T, Ariake K, Mizuma M, Nakagawa K, Morikawa T, Furukawa T, Unno M
BMC cancer 2023 Sep 6;23(1):835
BMC cancer 2023 Sep 6;23(1):835
A novel small molecule effectively ameliorates estrogen deficiency-induced osteoporosis by targeting the gut-bone signaling axis.
Chen C, Lei H, Zhao Y, Hou Y, Zheng H, Zhang C, Cao Z, Wu F, Chen G, Song Y, Zhang C, Zhou J, Lu Y, Xie D, Zhang L
European journal of pharmacology 2023 Sep 5;954:175868
European journal of pharmacology 2023 Sep 5;954:175868
1,8-Cineole ameliorates endothelial injury and hypertension induced by L-NAME through regulation of autophagy via PI3K/mTOR signaling pathway.
Chen M, Hu Q, Wang S, Tao L, Hu X, Shen X
European journal of pharmacology 2023 Sep 5;954:175863
European journal of pharmacology 2023 Sep 5;954:175863
Activation of TrkB signaling mitigates cerebellar anomalies caused by Rbm4-Bdnf deficiency.
Tsai YY, Shen CL, D D, Tsai CY, Tarn WY
Communications biology 2023 Sep 5;6(1):910
Communications biology 2023 Sep 5;6(1):910
Structural characterization of human RPA70N association with DNA damage response proteins.
Wu Y, Fu W, Zang N, Zhou C
eLife 2023 Sep 5;12
eLife 2023 Sep 5;12
A twin UGUA motif directs the balance between gene isoforms through CFIm and the mTORC1 signaling pathway.
Herron RS, Kunisky AK, Madden JR, Anyaeche VI, Maung MZ, Hwang HW
eLife 2023 Sep 4;12
eLife 2023 Sep 4;12
Preparation of a new resource food-arabinogalactan and its protective effect against enterotoxicity in IEC-6 cells by inhibiting endoplasmic reticulum stress.
Zhang S, Wang S, Fan YY, Liu WC, Zheng YN, Wang Z, Ren S, Li W
International journal of biological macromolecules 2023 Sep 30;249:126124
International journal of biological macromolecules 2023 Sep 30;249:126124
A multifunctional polydopamine/genipin/alendronate nanoparticle licences fibrin hydrogels osteoinductive and immunomodulatory potencies for repairing bone defects.
Shi W, Gao Y, Wu Y, Sun J, Xu B, Lu X, Wang Q
International journal of biological macromolecules 2023 Sep 30;249:126072
International journal of biological macromolecules 2023 Sep 30;249:126072
miR-491-5p regulates the susceptibility of glioblastoma to ferroptosis through TP53.
Jie XF, Li YP, Liu S, Fu Y, Xiong YY
Biochemical and biophysical research communications 2023 Sep 3;671:309-317
Biochemical and biophysical research communications 2023 Sep 3;671:309-317
Hesperidin inhibits methylation and autophagy in LPS and high glucose-induced human villous trophoblasts.
Chen Q, Hu K, Shi J, Li H, Li W
Biochemical and biophysical research communications 2023 Sep 3;671:278-285
Biochemical and biophysical research communications 2023 Sep 3;671:278-285
Gastrodin relieves cognitive impairment by regulating autophagy via PI3K/AKT signaling pathway in vascular dementia.
Chen YX, Yang H, Wang DS, Yao YT, Chen TT, Tao L, Chen Y, Shen XC
Biochemical and biophysical research communications 2023 Sep 3;671:246-254
Biochemical and biophysical research communications 2023 Sep 3;671:246-254
Antidiabetic Effect of Collagen Peptides from Harpadon nehereus Bones in Streptozotocin-Induced Diabetes Mice by Regulating Oxidative Stress and Glucose Metabolism.
Lin Q, Guo Y, Li J, He S, Chen Y, Jin H
Marine drugs 2023 Sep 29;21(10)
Marine drugs 2023 Sep 29;21(10)
HSP90B1-mediated plasma membrane localization of GLUT1 promotes radioresistance of glioblastomas.
Li Y, Ge Y, Zhao M, Ding F, Wang X, Shi Z, Ge X, Wang X, Qian X
Journal of biomedical research 2023 Sep 28;37(5):326-339
Journal of biomedical research 2023 Sep 28;37(5):326-339
The Gut Microbiota of Pregnant Rats Alleviates Fetal Growth Restriction by Inhibiting the TLR9/MyD88 Pathway.
Tang H, Li H, Li D, Peng J, Zhang X, Yang W
Journal of microbiology and biotechnology 2023 Sep 28;33(9):1213-1227
Journal of microbiology and biotechnology 2023 Sep 28;33(9):1213-1227
Benzophenanthridine Alkaloid Chelerythrine Elicits Necroptosis of Gastric Cancer Cells via Selective Conjugation at the Redox Hyperreactive C-Terminal Sec(498) Residue of Cytosolic Selenoprotein Thioredoxin Reductase.
Liu M, Sun S, Meng Y, Wang L, Liu H, Shi W, Zhang Q, Xu W, Sun B, Xu J
Molecules (Basel, Switzerland) 2023 Sep 28;28(19)
Molecules (Basel, Switzerland) 2023 Sep 28;28(19)
PUF60 promotes cell cycle and lung cancer progression by regulating alternative splicing of CDC25C.
Xu N, Ren Y, Bao Y, Shen X, Kang J, Wang N, Wang Z, Han X, Li Z, Zuo J, Wei GH, Wang Z, Zong WX, Liu W, Xie G, Wang Y
Cell reports 2023 Sep 26;42(9):113041
Cell reports 2023 Sep 26;42(9):113041
PM2.5 leads to adverse pregnancy outcomes by inducing trophoblast oxidative stress and mitochondrial apoptosis via KLF9/CYP1A1 transcriptional axis.
Li S, Li L, Zhang C, Fu H, Yu S, Zhou M, Guo J, Fang Z, Li A, Zhao M, Zhang M, Wang X
eLife 2023 Sep 22;12
eLife 2023 Sep 22;12
TSWIFT, a novel method for iterative staining of embedded and mounted human brain sections.
Porter CM, Truttmann MC
bioRxiv : the preprint server for biology 2023 Sep 22;
bioRxiv : the preprint server for biology 2023 Sep 22;
Glucose Starvation Stimulates the Promoting Strength of a Novel Evolved Suc2 Promoter.
Wang B, Zhao X, Fu T, Chen X, Guo X, Li X, Yang F
Journal of agricultural and food chemistry 2023 Sep 20;71(37):13838-13847
Journal of agricultural and food chemistry 2023 Sep 20;71(37):13838-13847
[miRNA-128-3p inhibits malignant behavior of glioma cells by downregulating KLHDC8A expression].
Yu Z, Li J, Jiang J, Li Y, Lin L, Xia Y, Wang L
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Sep 20;43(9):1447-1459
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Sep 20;43(9):1447-1459
A Unique G-Quadruplex Aptamer: A Novel Approach for Cancer Cell Recognition, Cell Membrane Visualization, and RSV Infection Detection.
Xiao CD, Zhong MQ, Gao Y, Yang ZL, Jia MH, Hu XH, Xu Y, Shen XC
International journal of molecular sciences 2023 Sep 20;24(18)
International journal of molecular sciences 2023 Sep 20;24(18)
Icariin-Curcumol promotes docetaxel sensitivity in prostate cancer through modulation of the PI3K-Akt signaling pathway and the Warburg effect.
Xu W, Ding J, Kuang S, Li B, Sun T, Zhu C, Liu J, Zhu L, Li Y, Sheng W
Cancer cell international 2023 Sep 2;23(1):190
Cancer cell international 2023 Sep 2;23(1):190
Lactobacillus fermentum Alleviates the Colorectal Inflammation Induced by Low-Dose Sub-Chronic Microcystin-LR Exposure.
Yang Y, Wen C, Zheng S, Song F, Liu Y, Yao X, Tang Y, Feng X, Chen J, Yang F
Toxins 2023 Sep 19;15(9)
Toxins 2023 Sep 19;15(9)
Long-Term Exposure to Microcystin-LR Induces Gastric Toxicity by Activating the Mitogen-Activated Protein Kinase Signaling Pathway.
Liu Y, Li Y, Tan Q, Lv Y, Tang Y, Yang Y, Yao X, Yang F
Toxins 2023 Sep 18;15(9)
Toxins 2023 Sep 18;15(9)
Rosmarinic acid ameliorates autoimmune responses through suppression of intracellular nucleic acid-mediated type I interferon expression.
Li XW, Yuan SC, Wang M, Su ZH, Zhao M, Li T, Zhang XM, Xue W, Li WH
Biochemical and biophysical research communications 2023 Sep 17;673:73-80
Biochemical and biophysical research communications 2023 Sep 17;673:73-80
Specific inhibitory effects of guanosine on breast cancer cell proliferation.
Takizawa Y, Kizawa M, Niwa N, Komura Y, Takahashi M, Koda D, Kurita T, Nakajima T
Biochemical and biophysical research communications 2023 Sep 17;673:67-72
Biochemical and biophysical research communications 2023 Sep 17;673:67-72
Hypoxic Preconditioning Enhances Cellular Viability and Migratory Ability: Role of DANCR/miR-656-3p/HIF-1α Axis in Placental Mesenchymal Stem Cells.
Haoran S, Zhishan J, Yan M, Ruilin M, Jianjian C, Zejun Y, Jianwen Z, Hui G, Yin Z
Stem cells (Dayton, Ohio) 2023 Sep 15;41(9):877-891
Stem cells (Dayton, Ohio) 2023 Sep 15;41(9):877-891
Ginsenoside Rg1 attenuates diabetic vascular endothelial dysfunction by inhibiting the calpain-1/ROS/PKC-β axis.
Lu M, Zhao F, Ran C, Xu Y, Zhang J, Wang H
Life sciences 2023 Sep 15;329:121972
Life sciences 2023 Sep 15;329:121972
Modified Gegen Qinlian decoction ameliorated ulcerative colitis by attenuating inflammation and oxidative stress and enhancing intestinal barrier function in vivo and in vitro.
Wang Y, Zhang J, Zhang B, Lu M, Ma J, Liu Z, Huang J, Ma J, Yang X, Wang F, Tang X
Journal of ethnopharmacology 2023 Sep 15;313:116538
Journal of ethnopharmacology 2023 Sep 15;313:116538
Congenital cataracts affect the retinal visual cycle and mitochondrial function: A multi-omics study of GJA8 knockout rabbits.
Sun W, Gu S, Zhang F, Xu M, Chang P, Zhao Y
Journal of proteomics 2023 Sep 15;287:104972
Journal of proteomics 2023 Sep 15;287:104972
ATG7 upregulation contributes to malignant transformation of human bronchial epithelial cells by B[a]PDE via DNMT3B protein degradation and miR-494 promoter methylation.
Tian Z, Hua X, Zhu J, Li P, Chen R, Li X, Li T, Zhou C, Huang C
Ecotoxicology and environmental safety 2023 Sep 15;263:115273
Ecotoxicology and environmental safety 2023 Sep 15;263:115273
Cadmium exposure promotes ferroptosis by upregulating Heat Shock Protein 70 in vascular endothelial damage of zebrafish.
Zhang T, Yan W, Liu C, Duan W, Duan Y, Li Y, Yu Q, Sun Y, Tian J, Zhou J, Xia Z, Wang G, Xu S
Ecotoxicology and environmental safety 2023 Sep 15;263:115241
Ecotoxicology and environmental safety 2023 Sep 15;263:115241
A stepwise and digital pattern of RSK phosphorylation determines the outcome of thymic selection.
Funasaki S, Hatano A, Nakatsumi H, Koga D, Sugahara O, Yumimoto K, Baba M, Matsumoto M, Nakayama KI
iScience 2023 Sep 15;26(9):107552
iScience 2023 Sep 15;26(9):107552
Systemic gene therapy using an AAV44.9 vector rescues a neonatal lethal mouse model of propionic acidemia.
Chandler RJ, Di Pasquale G, Choi EY, Chang D, Smith SN, Sloan JL, Hoffmann V, Li L, Chiorini JA, Venditti CP
Molecular therapy. Methods & clinical development 2023 Sep 14;30:181-190
Molecular therapy. Methods & clinical development 2023 Sep 14;30:181-190
Solar ultraviolet B radiation promotes α-MSH secretion to attenuate the function of ILC2s via the pituitary-lung axis.
Huang Y, Zhu L, Cheng S, Dai R, Huang C, Song Y, Peng B, Li X, Wen J, Gong Y, Hu Y, Qian L, Zhu L, Zhang F, Yu L, Yi C, Gu W, Ling Z, Ma L, Tang W, Peng L, Shi G, Zhang Y, Sun B
Nature communications 2023 Sep 12;14(1):5601
Nature communications 2023 Sep 12;14(1):5601
Oxidative stress mediates hippocampal neuronal apoptosis through ROS/JNK/P53 pathway in rats with PTSD triggered by high-voltage electrical burn.
Lv Y, Zhao X, Zhang R, He Z, Xu Y, Tu L, Jiang L, Xu S, Zhang Q
Folia morphologica 2023 Sep 11;
Folia morphologica 2023 Sep 11;
Codium fragile Suppressed Chronic PM(2.5)-Exposed Pulmonary Dysfunction via TLR/TGF-β Pathway in BALB/c Mice.
Kim TY, Kim JM, Lee HL, Go MJ, Joo SG, Kim JH, Lee HS, Jeong WM, Lee DY, Kim HJ, Heo HJ
Antioxidants (Basel, Switzerland) 2023 Sep 10;12(9)
Antioxidants (Basel, Switzerland) 2023 Sep 10;12(9)
Long-term iTBS Improves Neural Functional Recovery by Reducing the Inflammatory Response and Inhibiting Neuronal Apoptosis Via miR-34c-5p/p53/Bax Signaling Pathway in Cerebral Ischemic Rats.
Hu S, Wang X, Yang X, Ouyang S, Pan X, Fu Y, Wu S
Neuroscience 2023 Sep 1;527:37-51
Neuroscience 2023 Sep 1;527:37-51
Gambogenic acid induces cell death in human osteosarcoma through altering iron metabolism, disturbing the redox balance, and activating the P53 signaling pathway.
Liu Z, Wang X, Li J, Yang X, Huang J, Ji C, Li X, Li L, Zhou J, Hu Y
Chemico-biological interactions 2023 Sep 1;382:110602
Chemico-biological interactions 2023 Sep 1;382:110602
Epithelial TIPE1 Protein Guards against Colitis by Inhibiting TNF-α-Mediated Inflammation.
Lou Y, Jiang S, Song M, Wang H, Han M, Tian X, Zhao Y, Gao J, Song Y, Ma S, Zhao P, Zheng Q, Niu Z, Zhang W, Chang T, Chen YH, Wang H
Journal of immunology (Baltimore, Md. : 1950) 2023 Sep 1;211(5):874-884
Journal of immunology (Baltimore, Md. : 1950) 2023 Sep 1;211(5):874-884
TGR5 supresses cGAS/STING pathway by inhibiting GRP75-mediated endoplasmic reticulum-mitochondrial coupling in diabetic retinopathy.
Li Y, Zhu L, Cai MX, Wang ZL, Zhuang M, Tan CY, Xie TH, Yao Y, Wei TT
Cell death & disease 2023 Sep 1;14(9):583
Cell death & disease 2023 Sep 1;14(9):583
DSTN Hypomethylation Promotes Radiotherapy Resistance of Rectal Cancer by Activating the Wnt/β-Catenin Signaling Pathway.
Wen R, Zhou L, Jiang S, Fan H, Zheng K, Yu Y, Gao X, Hao L, Lou Z, Yu G, Yang F, Zhang W
International journal of radiation oncology, biology, physics 2023 Sep 1;117(1):198-210
International journal of radiation oncology, biology, physics 2023 Sep 1;117(1):198-210
RBM15‑mediating MDR1 mRNA m(6)A methylation regulated by the TGF‑β signaling pathway in paclitaxel‑resistant ovarian cancer.
Yuan J, Guan W, Li X, Wang F, Liu H, Xu G
International journal of oncology 2023 Oct;63(4)
International journal of oncology 2023 Oct;63(4)
Ghrelin inhibits NLRP3 inflammasome activation by upregulating autophagy to improve Alzheimer's disease.
Guo Y, Zhang L
In vitro cellular & developmental biology. Animal 2023 Oct;59(9):665-673
In vitro cellular & developmental biology. Animal 2023 Oct;59(9):665-673
Quercetin promotes autophagy to alleviate cigarette smoke-related periodontitis.
Yu J, Jing Z, Shen D, Yang M, Liu K, Xiang K, Zhou C, Gong X, Deng Y, Li Y, Yang S
Journal of periodontal research 2023 Oct;58(5):1082-1095
Journal of periodontal research 2023 Oct;58(5):1082-1095
Molecular classification of hormone receptor-positive HER2-negative breast cancer.
Jin X, Zhou YF, Ma D, Zhao S, Lin CJ, Xiao Y, Fu T, Liu CL, Chen YY, Xiao WX, Liu YQ, Chen QW, Yu Y, Shi LM, Shi JX, Huang W, Robertson JFR, Jiang YZ, Shao ZM
Nature genetics 2023 Oct;55(10):1696-1708
Nature genetics 2023 Oct;55(10):1696-1708
Fine particulate matter promotes airway inflammation and mucin production by activating endoplasmic reticulum stress and the IRE1α/NOD1/NF‑κB pathway.
Hu L, Xu C, Tang X, Yu S, Wang L, Li Q, Zhou X
International journal of molecular medicine 2023 Oct;52(4)
International journal of molecular medicine 2023 Oct;52(4)
Loss of hepatic FTCD promotes lipid accumulation and hepatocarcinogenesis by upregulating PPARγ and SREBP2.
Wang S, Zhou Y, Yu R, Ling J, Li B, Yang C, Cheng Z, Qian R, Lin Z, Yu C, Zheng J, Zheng X, Jia Q, Wu W, Wu Q, Chen M, Yuan S, Dong W, Shi Y, Jansen R, Yang C, Hao Y, Yao M, Qin W, Jin H
JHEP reports : innovation in hepatology 2023 Oct;5(10):100843
JHEP reports : innovation in hepatology 2023 Oct;5(10):100843
IGF-1 Combined with OPN Promotes Neuronal Axon Growth in Vitro Through the IGF-1R/Akt/mTOR Signaling Pathway in Lipid Rafts.
Zhao Q, Su H, Jiang W, Luo H, Pan L, Liu Y, Yang C, Yin Y, Yu L, Tan B
Neurochemical research 2023 Oct;48(10):3190-3201
Neurochemical research 2023 Oct;48(10):3190-3201
VCAM-1(+) hUC-MSCs Exert Considerable Neuroprotection Against Cerebral Infarction in Rats by Suppression of NLRP3-Induced Pyroptosis.
Zhang X, Sang X, Chen Y, Yu H, Sun Y, Liang X, Zheng X, Wang X, Yang H, Bi J, Zhang L, Wang P
Neurochemical research 2023 Oct;48(10):3084-3098
Neurochemical research 2023 Oct;48(10):3084-3098
Pregnane X receptor activation alleviates renal fibrosis in mice via interacting with p53 and inhibiting the Wnt7a/β-catenin signaling.
Ming WH, Luan ZL, Yao Y, Liu HC, Hu SY, Du CX, Zhang C, Zhao YH, Huang YZ, Sun XW, Qiao RF, Xu H, Guan YF, Zhang XY
Acta pharmacologica Sinica 2023 Oct;44(10):2075-2090
Acta pharmacologica Sinica 2023 Oct;44(10):2075-2090
miR-188-5p silencing improves cerebral ischemia/reperfusion injury by targeting Lin28a.
Hou D, Pei C, Yu D, Yang G
Metabolic brain disease 2023 Oct;38(7):2327-2338
Metabolic brain disease 2023 Oct;38(7):2327-2338
The potential mechanism of Choulingdan mixture in improving acute lung injury based on HPLC-Q-TOF-MS, network pharmacology and in vivo experiments.
Wang L, Li Z, Lu T, Su L, Mao C, Zhang Y, Zhang X, Jiang X, Xie H, Yu X
Biomedical chromatography : BMC 2023 Oct;37(10):e5709
Biomedical chromatography : BMC 2023 Oct;37(10):e5709
Bavachinin selectively modulates PPAR γ and maintains bone homeostasis in Type 2 Diabetes.
Liu J, Li X, Wang H, Ren Y, Li Y, Guo F
Phytotherapy research : PTR 2023 Oct;37(10):4457-4472
Phytotherapy research : PTR 2023 Oct;37(10):4457-4472
Paternal cadmium exposure induces glucolipid metabolic reprogramming in offspring mice via PPAR signaling pathway.
Zeng L, Zhou J, Zhang Y, Wang X, Li Y, Song J, Shao J, Su P
Chemosphere 2023 Oct;339:139592
Chemosphere 2023 Oct;339:139592
BCKDHA contributes to melanoma progression by promoting the expressions of lipogenic enzymes FASN and ACLY.
Tian Y, Ma J, Wang M, Yi X, Guo S, Wang H, Zhang H, Wang H, Yang Y, Zhang B, Du J, Shi Q, Gao T, Li C, Guo W
Experimental dermatology 2023 Oct;32(10):1633-1643
Experimental dermatology 2023 Oct;32(10):1633-1643
Filamin A facilitates NLRP3 inflammasome activation during arsenic-induced nonalcoholic steatohepatitis.
Shi Y, Qiu T, Wu C, Yuan W, Yao X, Jiang L, Wang N, Wang L, Han Q, Yang G, Liu X, Sun X
Environmental science and pollution research international 2023 Oct;30(49):107703-107715
Environmental science and pollution research international 2023 Oct;30(49):107703-107715
The E3 ubiquitin ligase TRIM17 promotes gastric cancer survival and progression via controlling BAX stability and antagonizing apoptosis.
Shen J, Yang H, Qiao X, Chen Y, Zheng L, Lin J, Lang J, Yu Q, Wang Z
Cell death and differentiation 2023 Oct;30(10):2322-2335
Cell death and differentiation 2023 Oct;30(10):2322-2335
LncRNA BCAN-AS1 stabilizes c-Myc via N(6)-methyladenosine-mediated binding with SNIP1 to promote pancreatic cancer.
Wu G, Su J, Zeng L, Deng S, Huang X, Ye Y, Li R, Bai R, Zhuang L, Li M, Zhou Q, Zheng Y, Deng J, Zhang S, Chen R, Lin D, Zhang J, Zheng J
Cell death and differentiation 2023 Oct;30(10):2213-2230
Cell death and differentiation 2023 Oct;30(10):2213-2230
DJ-1-mediated p62 degradation delays intervertebral disc degeneration by inhibiting apoptosis of nucleus pulposus cells.
Lin J, Zheng X, Xiong Z, Xiang Q, Zhao Y, Jiang S, Sun Z, Fan D, Sun C, Li W
Apoptosis : an international journal on programmed cell death 2023 Oct;28(9-10):1357-1371
Apoptosis : an international journal on programmed cell death 2023 Oct;28(9-10):1357-1371
Oncogenic roles of GPR176 in breast cancer: a potential marker of aggressiveness and a potential target of gene therapy.
Yun WJ, Xue H, Yang N, Xiao LJ, Sun HZ, Zheng HC
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 Oct;25(10):3042-3056
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 Oct;25(10):3042-3056
CRISPR/SaCas9-based gene editing rescues photoreceptor degeneration throughout a rhodopsin-associated autosomal dominant retinitis pigmentosa mouse model.
Du W, Li J, Tang X, Yu W, Zhao M
Experimental biology and medicine (Maywood, N.J.) 2023 Oct;248(20):1818-1828
Experimental biology and medicine (Maywood, N.J.) 2023 Oct;248(20):1818-1828
Functional analysis of two abnormal antithrombin proteins with different intracellular kinetics.
Imai Y, Nagaya S, Araiso Y, Meguro-Horike M, Togashi T, Horike SI, Kawasaki H, Morishita E
Thrombosis research 2023 Oct;230:18-26
Thrombosis research 2023 Oct;230:18-26
ACLY promotes gastric tumorigenesis and accelerates peritoneal metastasis of gastric cancer regulated by HIF-1A.
Yan Z, Liu K, Xu P, Chen Z, Zhang P, Pei S, Cheng Q, Huang S, Li B, Lv J, Xu Z, Xu H, Yang L, Zhang D
Cell cycle (Georgetown, Tex.) 2023 Oct;22(20):2288-2301
Cell cycle (Georgetown, Tex.) 2023 Oct;22(20):2288-2301
IGF2BP2 promotes glycolysis and hepatocellular carcinoma stemness by stabilizing CDC45 mRNA via m6A modification.
Wu T, Liao L, Wu T, Chen S, Yi Q, Xu M
Cell cycle (Georgetown, Tex.) 2023 Oct;22(20):2245-2263
Cell cycle (Georgetown, Tex.) 2023 Oct;22(20):2245-2263
EGFR suppression contributes to growth inhibitory activity of G-quadruplex ligands in non-small cell lung cancers.
Lu K, Wang HC, Tu YC, Lou PJ, Chang TC, Lin JJ
Biochemical pharmacology 2023 Oct;216:115788
Biochemical pharmacology 2023 Oct;216:115788
Histone methyltransferase SETD2 inhibits M1 macrophage polarization and glycolysis by suppressing HIF-1α in sepsis-induced acute lung injury.
Meng Y, Kong KW, Chang YQ, Deng XM, Yang T
Medical microbiology and immunology 2023 Oct;212(5):369-379
Medical microbiology and immunology 2023 Oct;212(5):369-379
FN1 mediated activation of aspartate metabolism promotes the progression of triple-negative and luminal a breast cancer.
Chen C, Ye L, Yi J, Liu T, Li Z
Breast cancer research and treatment 2023 Oct;201(3):515-533
Breast cancer research and treatment 2023 Oct;201(3):515-533
A sequential scheme including PTT and 2'3'-cGAMP/CQ-LP reveals the antitumor immune function of PTT through the type I interferon pathway.
Song X, Wang M, Liu S, Liu H, Jiang A, Zou Y, Deng Y, Qin Q, Song Y, Zheng Y
Pharmacological research 2023 Oct;196:106939
Pharmacological research 2023 Oct;196:106939
Ampelopsin attenuates Staphylococcus aureus Alpha-Toxin-Induced Lung Injury.
Wang Y, Tang M, Deng H, Hong Z, Liang Z, Huang Y, Zeng C, Yang K
Microbial pathogenesis 2023 Oct;183:106316
Microbial pathogenesis 2023 Oct;183:106316
Activation of Nrf2 signalling pathway by tectoridin protects against ferroptosis in particulate matter-induced lung injury.
Dong T, Fan X, Zheng N, Yan K, Hou T, Peng L, Ci X
British journal of pharmacology 2023 Oct;180(19):2532-2549
British journal of pharmacology 2023 Oct;180(19):2532-2549
6-Mercaptopurine potently inhibits recruitment of SHP2 by phosphorylated PD-1 to inhibit PD-1 signalling and enhance T cell function.
Liu L, Lei Y, Zheng Z, Zhou X, Chen S, Zeng G, Yu L, Wang P, Chen L
Immunology 2023 Oct;170(2):230-242
Immunology 2023 Oct;170(2):230-242
The role of the gut-microbiota-brain axis via the subdiaphragmatic vagus nerve in chronic inflammatory pain and comorbid spatial working memory impairment in complete Freund's adjuvant mice.
Yue C, Luan W, Gu H, Qiu D, Ding X, Liu P, Wang X, Hashimoto K, Yang JJ
Journal of psychiatric research 2023 Oct;166:61-73
Journal of psychiatric research 2023 Oct;166:61-73
Babao Dan alleviates gut immune and microbiota disorders while impacting the TLR4/MyD88/NF-кB pathway to attenuate 5-Fluorouracil-induced intestinal injury.
Huang B, Gui M, An H, Shen J, Ye F, Ni Z, Zhan H, Che L, Lai Z, Zeng J, Peng J, Lin J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115387
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115387
Undesirable ER stress induced by bavachin contributed to follicular atresia in zebrafish ovary.
Huang CS, Deng HF, Zhou L, Shen P, Ni YH, Wang NN, Li GF, Yue LX, Zhou YQ, Zhou W, Gao Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115322
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115322
Synthesis and biological evaluation of chromanone-based derivatives as potential anti-neuroinflammatory agents.
Li G, Feng X, Wang W, Li J, Shi Y, Wang L, Hu C
Bioorganic chemistry 2023 Oct;139:106767
Bioorganic chemistry 2023 Oct;139:106767
Cullin-associated and neddylation-dissociated 1 regulate reprogramming of lipid metabolism through SKP1-Cullin-1-F-box(FBXO11) -mediated heterogeneous nuclear ribonucleoprotein A2/B1 ubiquitination and promote hepatocellular carcinoma.
Zhang H, Xia P, Yang Z, Liu J, Zhu Y, Huang Z, Zhang Z, Yuan Y
Clinical and translational medicine 2023 Oct;13(10):e1443
Clinical and translational medicine 2023 Oct;13(10):e1443
Quercetin ameliorates nonalcoholic fatty liver disease (NAFLD) via the promotion of AMPK-mediated hepatic mitophagy.
Cao P, Wang Y, Zhang C, Sullivan MA, Chen W, Jing X, Yu H, Li F, Wang Q, Zhou Z, Wang Q, Tian W, Qiu Z, Luo L
The Journal of nutritional biochemistry 2023 Oct;120:109414
The Journal of nutritional biochemistry 2023 Oct;120:109414
Anti-rheumatoid arthritis effects of total saponins from Rhizoma Panacis Majoris on adjuvant-induced arthritis in rats and rheumatoid arthritis fibroblast-like synoviocytes.
Ren M, Ma K, Pang X, Liu Y, Song Z, Zhou R, Tang Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155021
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155021
OTUB1's role in promoting OSCC development by stabilizing RACK1 involves cell proliferation, migration, invasion, and tumor-associated macrophage M1 polarization.
Li Y, Li R, Qin H, He H, Li S
Cellular signalling 2023 Oct;110:110835
Cellular signalling 2023 Oct;110:110835
Puerarin protects against acetaminophen-induced oxidative damage in liver through activation of the Keap1/Nrf2 signaling pathway.
Zhou W, He H, Wei Q, Che L, Zhao X, Liu W, Yan Y, Hu L, Du Y, Yin Z, Shuai Y, Yang L, Feng R
Food science & nutrition 2023 Oct;11(10):6604-6615
Food science & nutrition 2023 Oct;11(10):6604-6615
CCDC50 promotes tumor growth through regulation of lysosome homeostasis.
Jia P, Tian T, Li Z, Wang Y, Lin Y, Zeng W, Ye Y, He M, Ni X, Pan J, Dong X, Huang J, Li CM, Guo D, Hou P
EMBO reports 2023 Oct 9;24(10):e56948
EMBO reports 2023 Oct 9;24(10):e56948
URI alleviates tyrosine kinase inhibitors-induced ferroptosis by reprogramming lipid metabolism in p53 wild-type liver cancers.
Ding Z, Pan Y, Shang T, Jiang T, Lin Y, Yang C, Pang S, Cui X, Wang Y, Feng XF, Xu M, Pei M, Chen Y, Li X, Ding J, Tan Y, Wang H, Dong L, Wang L
Nature communications 2023 Oct 7;14(1):6269
Nature communications 2023 Oct 7;14(1):6269
PI3K/mTOR inhibitors promote G6PD autophagic degradation and exacerbate oxidative stress damage to radiosensitize small cell lung cancer.
Deng H, Chen Y, Wang L, Zhang Y, Hang Q, Li P, Zhang P, Ji J, Song H, Chen M, Jin Y
Cell death & disease 2023 Oct 6;14(10):652
Cell death & disease 2023 Oct 6;14(10):652
Prefrontal cortex-specific Dcc deletion induces schizophrenia-related behavioral phenotypes and fail to be rescued by olanzapine treatment.
Sun J, Cong Q, Sun T, Xi S, Liu Y, Zeng R, Wang J, Zhang W, Gao J, Qian J, Qin S
European journal of pharmacology 2023 Oct 5;956:175940
European journal of pharmacology 2023 Oct 5;956:175940
C1632 inhibits ovarian cancer cell growth and migration by inhibiting LIN28 B/let-7/FAK signaling pathway and FAK phosphorylation.
Zhang Q, Shi M, Zheng R, Han H, Zhang X, Lin F
European journal of pharmacology 2023 Oct 5;956:175935
European journal of pharmacology 2023 Oct 5;956:175935
VPS41-mediated incomplete autophagy aggravates cadmium-induced apoptosis in mouse hepatocytes.
Wang T, Yan L, Wang L, Sun J, Qu H, Ma Y, Song R, Tong X, Zhu J, Yuan Y, Gu J, Bian J, Liu Z, Zou H
Journal of hazardous materials 2023 Oct 5;459:132243
Journal of hazardous materials 2023 Oct 5;459:132243
Inhibition of adult hippocampal neurogenesis induced by postoperative CD8 + T-cell infiltration is associated with cognitive decline later following surgery in adult mice.
Li X, Wang H, Zhang Q, Sun X, Zhang M, Wang G
Journal of neuroinflammation 2023 Oct 5;20(1):227
Journal of neuroinflammation 2023 Oct 5;20(1):227
STING/ACSL4 axis-dependent ferroptosis and inflammation promote hypertension-associated chronic kidney disease.
Gao L, Zhang J, Yang T, Jiang L, Liu X, Wang S, Wang X, Huang Y, Wang H, Zhang M, Gong T, Ma L, Li C, He C, Meng XM, Wu Y
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Oct 4;31(10):3084-3103
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Oct 4;31(10):3084-3103
miR-124 and VAMP3 Act Antagonistically in Human Neuroblastoma.
Zhang X, Yang C, Meng Z, Zhong H, Hou X, Wang F, Lu Y, Guo J, Zeng Y
International journal of molecular sciences 2023 Oct 4;24(19)
International journal of molecular sciences 2023 Oct 4;24(19)
Heme oxygenase-1 increases intracellular iron storage and suppresses inflammatory response of macrophages by inhibiting M1 polarization.
Tang X, Li Y, Zhao J, Liang L, Zhang K, Zhang X, Yu H, Du H
Metallomics : integrated biometal science 2023 Oct 4;15(10)
Metallomics : integrated biometal science 2023 Oct 4;15(10)
Aspartyl-tRNA synthetase 2 orchestrates iron-sulfur metabolism in hematopoietic stem cells via fine-tuning alternative RNA splicing.
Gu X, Li K, Zhang M, Chen Y, Zhou J, Yao C, Zang Y, He J, Wan J, Guo B
Cell reports 2023 Oct 31;42(10):113264
Cell reports 2023 Oct 31;42(10):113264
Mechanotransduction in response to ECM stiffening impairs cGAS immune signaling in tumor cells.
Liu Y, Yao X, Zhao Y, Fang D, Shi L, Yang L, Song G, Cai K, Li L, Deng Q, Li M, Luo Z
Cell reports 2023 Oct 31;42(10):113213
Cell reports 2023 Oct 31;42(10):113213
Intraperitoneal Injection of MCC950 Inhibits the Progression of Myopia in Form-Deprivation Myopic Mice.
Chen Z, Xiao K, Long Q
International journal of molecular sciences 2023 Oct 31;24(21)
International journal of molecular sciences 2023 Oct 31;24(21)
Caveolin-1 scaffolding domain peptide prevents corpus cavernosum fibrosis and erectile dysfunction in bilateral cavernous nerve injury-induced rats.
Xi Y, Ge Y, Hu D, Xia T, Chen J, Zhang C, Cui Y, Xiao H
The journal of sexual medicine 2023 Oct 31;20(11):1274-1284
The journal of sexual medicine 2023 Oct 31;20(11):1274-1284
Lactobacillus casei combined with Lactobacillus reuteri alleviate pancreatic cancer by inhibiting TLR4 to promote macrophage M1 polarization and regulate gut microbial homeostasis.
Zhu Z, Yi B, Tang Z, Chen X, Li M, Xu T, Zhao Z, Tang C
BMC cancer 2023 Oct 30;23(1):1044
BMC cancer 2023 Oct 30;23(1):1044
Comparison of Multiple Strategies for Precision Transgene Knock-In in Gallus gallus Genome via Microhomology-Mediated End Joining.
Wang L, Sun J, Liu Z, Zheng Q, Wang G
International journal of molecular sciences 2023 Oct 29;24(21)
International journal of molecular sciences 2023 Oct 29;24(21)
RNF149 Promotes HCC Progression through Its E3 Ubiquitin Ligase Activity.
Guo Z, Jiang P, Dong Q, Zhang Y, Xu K, Zhai Y, He F, Tian C, Sun A
Cancers 2023 Oct 29;15(21)
Cancers 2023 Oct 29;15(21)
Sirtuin1 Mediates the Protective Effects of Echinacoside against Sepsis-Induced Acute Lung Injury via Regulating the NOX4-Nrf2 Axis.
Xie W, Deng L, Lin M, Huang X, Qian R, Xiong D, Liu W, Tang S
Antioxidants (Basel, Switzerland) 2023 Oct 29;12(11)
Antioxidants (Basel, Switzerland) 2023 Oct 29;12(11)
Poria cocos Lanostane Triterpenoids Extract Promotes Collagen and Hyaluronic Acid Production in D-Galactose-Induced Aging Rats.
Chao CL, Kuo HP, Huang HW, Cheng MY, Chao HF, Lu SM, Lin HC, Wang CJ, Chang TC, Wu CR
Life (Basel, Switzerland) 2023 Oct 28;13(11)
Life (Basel, Switzerland) 2023 Oct 28;13(11)
Liensinine and neferine exert neuroprotective effects via the autophagy pathway in transgenic Caenorhabditis elegans.
Wu MC, Gao YH, Zhang C, Ma BT, Lin HR, Jiang JY, Xue MF, Li S, Wang HB
BMC complementary medicine and therapies 2023 Oct 27;23(1):386
BMC complementary medicine and therapies 2023 Oct 27;23(1):386
METTL3-regulated m6A modification impairs the decidualization of endometrial stromal cells by regulating YTHDF2-mediated degradation of FOXO1 mRNA in endometriosis-related infertility.
Li X, Jin J, Long X, Weng R, Xiong W, Liang J, Liu J, Sun J, Cai X, Zhang L, Liu Y
Reproductive biology and endocrinology : RB&E 2023 Oct 27;21(1):99
Reproductive biology and endocrinology : RB&E 2023 Oct 27;21(1):99
Leveraging a disulfidptosis-related signature to predict the prognosis and immunotherapy effectiveness of cutaneous melanoma based on machine learning.
Zhao Y, Wei Y, Fan L, Nie Y, Li J, Zeng R, Li J, Zhan X, Lei L, Kang Z, Li J, Zhang W, Yang Z
Molecular medicine (Cambridge, Mass.) 2023 Oct 26;29(1):145
Molecular medicine (Cambridge, Mass.) 2023 Oct 26;29(1):145
Cordyceps militaris Solid Medium Extract Alleviates Lipoteichoic Acid-Induced MH-S Inflammation by Inhibiting TLR2/NF-κB/NLRP3 Pathways.
Wang X, Peng Z, Wang L, Zhang J, Zhang K, Guo Z, Xu G, Li J
International journal of molecular sciences 2023 Oct 24;24(21)
International journal of molecular sciences 2023 Oct 24;24(21)
Nuclear respiratory factor 1 drives hepatocellular carcinoma progression by activating LPCAT1-ERK1/2-CREB axis.
Liu R, Yin C, Zhao P, Guo B, Ke W, Zheng X, Xie D, Wang Y, Wang G, Jia Y, Gao Y, Hu W, Liu GL, Song Z
Biology direct 2023 Oct 24;18(1):67
Biology direct 2023 Oct 24;18(1):67
Metformin inhibits inflammatory response and endoplasmic reticulum stress to improve hypothalamic aging in obese mice.
Yang L, Lu P, Qi X, Yang Q, Liu L, Dou T, Guan Q, Yu C
iScience 2023 Oct 20;26(10):108082
iScience 2023 Oct 20;26(10):108082
Dominant-negative HNF1α mutant promotes liver steatosis and inflammation by regulating hepatic complement factor D.
Liu M, Liu L, Guo H, Fan X, Liu T, Xu C, He Z, Song Y, Gao L, Shao S, Zhao J, Lu P
iScience 2023 Oct 20;26(10):108018
iScience 2023 Oct 20;26(10):108018
Focused low-intensity pulsed ultrasound alleviates osteoarthritis via restoring impaired FUNDC1-mediated mitophagy.
Ye H, Li D, Wei X, Yu L, Jia L
iScience 2023 Oct 20;26(10):107772
iScience 2023 Oct 20;26(10):107772
CHIP protects against septic acute kidney injury by inhibiting NLRP3-mediated pyroptosis.
Zhang H, Deng Z, Wang Y, Zheng X, Zhou L, Yan S, Wang Y, Dai Y, Kanwar YS, Deng F
iScience 2023 Oct 20;26(10):107762
iScience 2023 Oct 20;26(10):107762
African Swine Fever Virus pF778R Attenuates Type I Interferon Response by Impeding STAT1 Nuclear Translocation.
Chen Q, Li L, Liu L, Liu Z, Guo S, Tan C, Chen H, Wang X
Virus research 2023 Oct 2;335:199190
Virus research 2023 Oct 2;335:199190
Identification of KLHDC2 as an efficient proximity-induced degrader of K-RAS, STK33, β-catenin, and FoxP3.
Röth S, Kocaturk NM, Sathyamurthi PS, Carton B, Watt M, Macartney TJ, Chan KH, Isidro-Llobet A, Konopacka A, Queisser MA, Sapkota GP
Cell chemical biology 2023 Oct 19;30(10):1261-1276.e7
Cell chemical biology 2023 Oct 19;30(10):1261-1276.e7
Insulin-induced gene 2 protects against hepatic ischemia-reperfusion injury via metabolic remodeling.
Wu Y, Li C, Khan AA, Chen K, Su R, Xu S, Sun Y, Gao F, Wang K, Wang X, Lian Z, Wang S, Yu M, Hu X, Yang F, Zheng S, Qiu N, Liu Z, Xu X
Journal of translational medicine 2023 Oct 19;21(1):739
Journal of translational medicine 2023 Oct 19;21(1):739
Targeting neoadjuvant chemotherapy-induced metabolic reprogramming in pancreatic cancer promotes anti-tumor immunity and chemo-response.
Tang R, Xu J, Wang W, Meng Q, Shao C, Zhang Y, Lei Y, Zhang Z, Liu Y, Du Q, Sun X, Wu D, Liang C, Hua J, Zhang B, Yu X, Shi S, Chinese Study Group for Pancreatic Cancer
Cell reports. Medicine 2023 Oct 17;4(10):101234
Cell reports. Medicine 2023 Oct 17;4(10):101234
Posttranslational ISGylation of NLRP3 by HERC enzymes facilitates inflammasome activation in models of inflammation.
Qin Y, Meng X, Wang M, Liang W, Xu R, Chen J, Song H, Fu Y, Li J, Gao C, Jia M, Zhao C, Zhao W
The Journal of clinical investigation 2023 Oct 16;133(20)
The Journal of clinical investigation 2023 Oct 16;133(20)
PI3K/mTOR inhibitor VS-5584 combined with PLK1 inhibitor exhibits synergistic anti-cancer effects on non-small cell lung cancer.
Zhao S, Li Y, Li G, Ye J, Wang R, Zhang X, Li F, Gao C, Li J, Jiang J, Mi Y
European journal of pharmacology 2023 Oct 15;957:176004
European journal of pharmacology 2023 Oct 15;957:176004
Silencing of ATP1A1 attenuates cell membrane disruption by nanosecond electric pulses.
Silkuniene G, Mangalanathan UM, Pakhomov AG, Pakhomova ON
Biochemical and biophysical research communications 2023 Oct 15;677:93-97
Biochemical and biophysical research communications 2023 Oct 15;677:93-97
Autophagy modulates the stability of Wee1 and cell cycle G2/M transition.
Han B, Chen Y, Song C, Chen Y, Chen Y, Ferguson D, Yang Y, He A
Biochemical and biophysical research communications 2023 Oct 15;677:63-69
Biochemical and biophysical research communications 2023 Oct 15;677:63-69
A unique inflammation-related mechanism by which high-fat diets induce depression-like behaviors in mice.
Yu H, Yu B, Qin X, Shan W
Journal of affective disorders 2023 Oct 15;339:180-193
Journal of affective disorders 2023 Oct 15;339:180-193
African swine fever virus MGF360-9L promotes viral replication by degrading the host protein HAX1.
Yang J, Yang B, Hao Y, Shi X, Yang X, Zhang D, Zhao D, Yan W, Chen L, Bie X, Chen G, Zhu Z, Li D, Shen C, Li G, Liu X, Zheng H, Zhang K
Virus research 2023 Oct 15;336:199198
Virus research 2023 Oct 15;336:199198
Downregulation of XBP1s aggravates lipopolysaccharide-induced inflammation by promoting NF-κB and NLRP3 pathways' activation in goat endometrial epithelial cells.
Gao K, Yi Y, Xue Z, Wang Z, Huang S, Zhang B, Lin P, Wang A, Chen H, Jin Y
Theriogenology 2023 Oct 15;210:119-132
Theriogenology 2023 Oct 15;210:119-132
Leptin Promotes the Proliferation and Neuronal Differentiation of Neural Stem Cells through the Cooperative Action of MAPK/ERK1/2, JAK2/STAT3 and PI3K/AKT Signaling Pathways.
Tan R, Hu X, Wang X, Sun M, Cai Z, Zhang Z, Fu Y, Chen X, An J, Lu H
International journal of molecular sciences 2023 Oct 13;24(20)
International journal of molecular sciences 2023 Oct 13;24(20)
Flubendazole Enhances the Inhibitory Effect of Paclitaxel via HIF1α/PI3K/AKT Signaling Pathways in Breast Cancer.
Zhou Y, Liao M, Li Z, Ye J, Wu L, Mou Y, Fu L, Zhen Y
International journal of molecular sciences 2023 Oct 12;24(20)
International journal of molecular sciences 2023 Oct 12;24(20)
METTL3/IGF2BP2 axis affects the progression of colorectal cancer by regulating m6A modification of STAG3.
Yi J, Peng F, Zhao J, Gong X
Scientific reports 2023 Oct 12;13(1):17292
Scientific reports 2023 Oct 12;13(1):17292
Peptide Characterization of Bovine Myocardium Hydrolysates and Its Ameliorative Effects on Doxorubicin-Induced Myocardial Injury in H9c2 Cells and in Mice.
Li W, Lv M, Zhang T, Zhou M, Zheng L, Song T, Zhao M
Journal of agricultural and food chemistry 2023 Oct 11;71(40):14562-14574
Journal of agricultural and food chemistry 2023 Oct 11;71(40):14562-14574
AP4M1 as a prognostic biomarker associated with cell proliferation, migration and immune regulation in hepatocellular carcinoma.
Peng Y, Li X, Kang K, Zhou Y
Cancer cell international 2023 Oct 11;23(1):235
Cancer cell international 2023 Oct 11;23(1):235
Comparing the value of mono- vs coculture for high-throughput compound screening in hematological malignancies.
Herbst SA, Kim V, Roider T, Schitter EC, Bruch PM, Liebers N, Kolb C, Knoll M, Lu J, Dreger P, Müller-Tidow C, Zenz T, Huber W, Dietrich S
Blood advances 2023 Oct 10;7(19):5925-5936
Blood advances 2023 Oct 10;7(19):5925-5936
Cryo-EM structure of severe fever with thrombocytopenia syndrome virus.
Du S, Peng R, Xu W, Qu X, Wang Y, Wang J, Li L, Tian M, Guan Y, Wang J, Wang G, Li H, Deng L, Shi X, Ma Y, Liu F, Sun M, Wei Z, Jin N, Liu W, Qi J, Liu Q, Liao M, Li C
Nature communications 2023 Oct 10;14(1):6333
Nature communications 2023 Oct 10;14(1):6333
Novel c-Myc G4 stabilizer EP12 promotes myeloma cytotoxicity by disturbing NF-κB signaling.
Yao R, Zhang Y, Zeng Y, Zhang Y, Liu L, Gao J
Experimental cell research 2023 Oct 1;431(1):113759
Experimental cell research 2023 Oct 1;431(1):113759
Inulin alleviates neuroinflammation and oxidative stress induced by perinatal 2-ethylhexyl diphenyl phosphate (EHDPHP) exposure in female mice and offspring.
Li XW, Qiu F, Liu Y, Chen LJ, Li JH, Liu JL, Yang JZ, Hsu C, Chen L, Zeng JH, Xie XL, Wang Q
Ecotoxicology and environmental safety 2023 Oct 1;264:115396
Ecotoxicology and environmental safety 2023 Oct 1;264:115396
Complement C1q drives microglia-dependent synaptic loss and cognitive impairments in a mouse model of lipopolysaccharide-induced neuroinflammation.
Wu X, Gao Y, Shi C, Tong J, Ma D, Shen J, Yang J, Ji M
Neuropharmacology 2023 Oct 1;237:109646
Neuropharmacology 2023 Oct 1;237:109646
Umbilical cord mesenchymal stem cell-conditioned medium inhibits microglial activation to ameliorate neuroinflammation in amyotrophic lateral sclerosis mice and cell models.
Tang J, Kang Y, Zhou Y, Chen Q, Lan J, Liu X, Peng Y
Brain research bulletin 2023 Oct 1;202:110760
Brain research bulletin 2023 Oct 1;202:110760
Dendrobium mixture ameliorates hepatic injury induced by insulin resistance in vitro and in vivo through the downregulation of AGE/RAGE/Akt signaling pathway.
Zhuang S, Zhou X, Yang X, Chang D, Chen T, Sun Y, Wang C, Zhang C, Jiang J, Chen Y, Lin X, Wang X, Yu W, Lin X, He C, Zheng Y, Zhang J, Shi H
Heliyon 2023 Nov;9(11):e22007
Heliyon 2023 Nov;9(11):e22007
Arginase2 mediates contrast-induced acute kidney injury via facilitating nitrosative stress in tubular cells.
Zhou LY, Liu K, Yin WJ, Xie YL, Wang JL, Zuo SR, Tang ZY, Wu YF, Zuo XC
Redox biology 2023 Nov;67:102929
Redox biology 2023 Nov;67:102929
Tobacco toxins induce osteoporosis through ferroptosis.
Jing Z, Li Y, Zhang H, Chen T, Yu J, Xu X, Zou Y, Wang X, Xiang K, Gong X, He P, Fu Y, Ren M, Ji P, Yang S
Redox biology 2023 Nov;67:102922
Redox biology 2023 Nov;67:102922
The novel β-TrCP protein isoform hidden in circular RNA confers trastuzumab resistance in HER2-positive breast cancer.
Wang S, Wang Y, Li Q, Li X, Feng X, Zeng K
Redox biology 2023 Nov;67:102896
Redox biology 2023 Nov;67:102896
TRIM16 E121D variant affects the risk and prognosis of hepatocellular carcinoma by modulating the Wnt/β-catenin pathway.
Li S, Wang J, Chen H, Hou J, Shen T, Li J, Zhou B, Zhang B, Liu H, Jiang DK
Molecular carcinogenesis 2023 Nov;62(11):1686-1699
Molecular carcinogenesis 2023 Nov;62(11):1686-1699
LKB1 loss promotes colorectal cancer cell metastasis through regulating TNIK expression and actin cytoskeleton remodeling.
Hu G, Huang N, Zhang J, Zhang D, Wang S, Zhang Y, Wang L, Du Y, Kuang S, Ma K, Zhu H, Xu N, Liu M
Molecular carcinogenesis 2023 Nov;62(11):1659-1672
Molecular carcinogenesis 2023 Nov;62(11):1659-1672
Rutaecarpine Mitigates Cognitive Impairment by Balancing Mitochondrial Function Through Activation of the AMPK/PGC1α Pathway.
Gong M, Jia J
Molecular neurobiology 2023 Nov;60(11):6598-6612
Molecular neurobiology 2023 Nov;60(11):6598-6612
A new ferrocene derivative blocks K-Ras localization and function by oxidative modification at His95.
Rehl KM, Selvakumar J, Pitsch RL, Hoang D, Arumugam K, Harshman SW, Gorfe AA, Cho KJ
Life science alliance 2023 Nov;6(11)
Life science alliance 2023 Nov;6(11)
RNA‑binding protein quaking 5 inhibits the progression of non‑small cell lung cancer by upregulating netrin‑4 expression.
Wu Z, Liu S, Pang G, Jiang H
Oncology reports 2023 Nov;50(5)
Oncology reports 2023 Nov;50(5)
LncRNA MALAT1 Promoted Neuronal Necroptosis in Cerebral Ischemia-reperfusion Mice by Stabilizing HSP90.
Huang S, Hou D, Zhang L, Pei C, Liang J, Li J, Yang G, Yu D
Neurochemical research 2023 Nov;48(11):3457-3471
Neurochemical research 2023 Nov;48(11):3457-3471
Ginsenoside Rg5 promotes wound healing in diabetes by reducing the negative regulation of SLC7A11 on the efferocytosis of dendritic cells.
Xia W, Zhu Z, Xiang S, Yang Y
Journal of ginseng research 2023 Nov;47(6):784-794
Journal of ginseng research 2023 Nov;47(6):784-794
The cysteine-rich receptor-like kinase CRK4 contributes to the different drought stress response between Columbia and Landsberg erecta.
Zhao M, Li M, Huang M, Liang C, Chen D, Hwang I, Zhang W, Wang M
Plant, cell & environment 2023 Nov;46(11):3258-3272
Plant, cell & environment 2023 Nov;46(11):3258-3272
Inhibition of TMEM16A improves cisplatin-induced acute kidney injury via preventing DRP1-mediated mitochondrial fission.
Li XL, Liu XW, Liu WL, Lin YQ, Liu J, Peng YS, Cheng LM, Du YH
Acta pharmacologica Sinica 2023 Nov;44(11):2230-2242
Acta pharmacologica Sinica 2023 Nov;44(11):2230-2242
Cardiomyocyte peroxisome proliferator-activated receptor α prevents septic cardiomyopathy via improving mitochondrial function.
Zhu XX, Wang X, Jiao SY, Liu Y, Shi L, Xu Q, Wang JJ, Chen YE, Zhang Q, Song YT, Wei M, Yu BQ, Fielitz J, Gonzalez FJ, Du J, Qu AJ
Acta pharmacologica Sinica 2023 Nov;44(11):2184-2200
Acta pharmacologica Sinica 2023 Nov;44(11):2184-2200
Neuroprotective Effect of Hydrogen Sulfide Subchronic Treatment Against TBI-Induced Ferroptosis and Cognitive Deficits Mediated Through Wnt Signaling Pathway.
Chen J, Chen Z, Yu D, Yan Y, Hao X, Zhang M, Zhu T
Cellular and molecular neurobiology 2023 Nov;43(8):4117-4140
Cellular and molecular neurobiology 2023 Nov;43(8):4117-4140
Inflammatory Cell-Derived MYDGF Attenuates Endothelial LDL Transcytosis to Protect Against Atherogenesis.
Xu J, Ma H, Shi L, Zhou H, Cheng Y, Tong J, Meng B, Xu X, He K, Ding S, Zhang J, Yue L, Xiang G
Arteriosclerosis, thrombosis, and vascular biology 2023 Nov;43(11):e443-e467
Arteriosclerosis, thrombosis, and vascular biology 2023 Nov;43(11):e443-e467
UBE3B promotes breast cancer progression by antagonizing HIF-2α degradation.
Wang Y, Liu X, Wang M, Wang Y, Wang S, Jin L, Liu M, Zhou J, Chen Y
Oncogene 2023 Nov;42(46):3394-3406
Oncogene 2023 Nov;42(46):3394-3406
Fusaric acid inhibits proliferation and induces apoptosis through triggering endoplasmic reticulum stress in MCF-7 human breast cancer cells.
Zhang J, Yuan H, Li W, Chen S, Liu S, Li C, Yao X
Mycotoxin research 2023 Nov;39(4):347-364
Mycotoxin research 2023 Nov;39(4):347-364
Genetic Architecture and Functional Implications of the CSF-Contacting Nucleus.
Song S, Yuan Y, Xu L, Jiang J, Li Y, Yan Y, Li Q, Zhou F, Cao J, Zhang L
Neuroscience bulletin 2023 Nov;39(11):1638-1654
Neuroscience bulletin 2023 Nov;39(11):1638-1654
UFMylation of HRD1 regulates endoplasmic reticulum homeostasis.
Luo H, Jiao QB, Shen CB, Gong WY, Yuan JH, Liu YY, Chen Z, Liu J, Xu XL, Cong YS, Zhang XW
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23221
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23221
RUNX1 promotes proliferation and migration in non-small cell lung cancer cell lines via the mTOR pathway.
Ma H, Jiang S, Yuan Y, Li J, Li Y, Lv Y, Du T, Guan J, Jiang X, Tian L, Zheng Q, Yang L, Li Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23195
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23195
Potent gene delivery from fluorinated poly(β-amino ester) in adhesive and suspension difficult-to-transfect cells for apoptosis and ferroptosis.
Deng Y, Zhang J, Sun X, Li L, Zhou M, Liu S, Chen F, Pan C, Yu Z, Li M, Zhong W, Zeng M
Journal of controlled release : official journal of the Controlled Release Society 2023 Nov;363:597-605
Journal of controlled release : official journal of the Controlled Release Society 2023 Nov;363:597-605
Neuropathological hallmarks in autopsied cases with mitochondrial diseases caused by the mitochondrial 3243A>G mutation.
Miyahara H, Tamai C, Inoue M, Sekiguchi K, Tahara D, Tahara N, Takeda K, Arafuka S, Moriyoshi H, Koizumi R, Akagi A, Riku Y, Sone J, Yoshida M, Ihara K, Iwasaki Y
Brain pathology (Zurich, Switzerland) 2023 Nov;33(6):e13199
Brain pathology (Zurich, Switzerland) 2023 Nov;33(6):e13199
M2 macrophage exosomal LINC01001 promotes non-small cell lung cancer development by affecting METTL3 and glycolysis pathway.
Xu L, Li K, Li J, Xu F, Liang S, Kong Y, Chen B
Cancer gene therapy 2023 Nov;30(11):1569-1580
Cancer gene therapy 2023 Nov;30(11):1569-1580
Targeting SOD1 via RNAi with PEGylated graphene oxide nanoparticles in platinum-resistant ovarian cancer.
Szénási A, Sivasudhan E, Du H, Zhang P, Huang J, Zhang Z, Rocha S, Wang M
Cancer gene therapy 2023 Nov;30(11):1554-1568
Cancer gene therapy 2023 Nov;30(11):1554-1568
Combination of hyperlipidemia and 17β-Estradiol induces TMJOA-like pathological changes in rats.
Zhao Y, Gan YH
Oral diseases 2023 Nov;29(8):3640-3653
Oral diseases 2023 Nov;29(8):3640-3653
Involvement of ferroptosis in Porphyromonas gingivalis lipopolysaccharide-stimulated periodontitis in vitro and in vivo.
Qiao S, Li B, Cai Q, Li Z, Yin Z, He J, Li Y, Meng W
Oral diseases 2023 Nov;29(8):3571-3582
Oral diseases 2023 Nov;29(8):3571-3582
Acetyl zingerone ameliorates osteoarthritis by inhibiting chondrocyte programmed cell death.
Chen X, Chen J, Miao C, Yin G, Zhang Z, Sun R, Ni S
Molecular medicine reports 2023 Nov;28(5)
Molecular medicine reports 2023 Nov;28(5)
Knockdown of Bach1 protects periodontal bone regeneration from inflammatory damage.
Yuan Z, Li J, Zou X, Liu C, Lu J, Ni C, Tang L, Wu X, Yan F
Journal of cellular and molecular medicine 2023 Nov;27(22):3465-3477
Journal of cellular and molecular medicine 2023 Nov;27(22):3465-3477
Transcriptomics and metabolomics study in mouse kidney of the molecular mechanism underlying energy metabolism response to hypoxic stress in highland areas.
Gao Y, Long Q, Yang H, Hu Y, Xu Y, Tang C, Gu C, Yong S
Experimental and therapeutic medicine 2023 Nov;26(5):533
Experimental and therapeutic medicine 2023 Nov;26(5):533
An HPK1 inhibitor enhanced the tumour response to anti-PD-1 immunotherapy in non-Hodgkin's lymphoma.
Yang L, Zhao Q, Chen T, Liu W, Qiu X, Chen J, Huang S, Huang R, Dong L
Clinical and experimental medicine 2023 Nov;23(7):3767-3780
Clinical and experimental medicine 2023 Nov;23(7):3767-3780
Mulberry leaf flavonoids activate BAT and induce browning of WAT to improve type 2 diabetes via regulating the AMPK/SIRT1/PGC-1α signaling pathway.
Cheng L, Shi L, He C, Wang C, Lv Y, Li H, An Y, Duan Y, Dai H, Zhang H, Huang Y, Fu W, Sun W, Zhao B
Chinese journal of natural medicines 2023 Nov;21(11):812-829
Chinese journal of natural medicines 2023 Nov;21(11):812-829
Sphingosine kinase 1/S1P receptor signaling axis is essential for cellular uptake of Neisseria meningitidis in brain endothelial cells.
Fohmann I, Weinmann A, Schumacher F, Peters S, Prell A, Weigel C, Spiegel S, Kleuser B, Schubert-Unkmeir A
PLoS pathogens 2023 Nov;19(11):e1011842
PLoS pathogens 2023 Nov;19(11):e1011842
Autophagy regulation and protein kinase activity of PIK3C3 controls sertoli cell polarity through its negative regulation on SCIN (scinderin).
Wang K, Kong F, Qiu Y, Chen T, Fu J, Jin X, Su Y, Gu Y, Hu Z, Li J
Autophagy 2023 Nov;19(11):2934-2957
Autophagy 2023 Nov;19(11):2934-2957
Ferroptosis inhibition protects vascular endothelial cells and maintains integrity of the blood-spinal cord barrier after spinal cord injury.
Li W, Zhao X, Zhang R, Liu X, Qi Z, Zhang Y, Yang W, Pang Y, Zhao C, Fan B, Ran N, Zhang J, Kong X, Feng S, Yao X
Neural regeneration research 2023 Nov;18(11):2474-2481
Neural regeneration research 2023 Nov;18(11):2474-2481
Angelica sinensis polysaccharides ameliorated 5-Fluorouracil-induced damage of early B cell progenitors by alleviating oxidative stress of IL-7 producing mesenchymal stem and progenitor cells.
Xiao H, Wang Y, Wang Z, Wang B, Hu L, Hou J, Du K, Sun N, Wang L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115599
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115599
Fructus Lycii and Salvia miltiorrhiza Bunge extract attenuate oxidative stress-induced photoreceptor ferroptosis in retinitis pigmentosa.
Yang Y, Wang Y, Deng Y, Lu J, Xiao L, Li J, Zhou Y, Nie F, Chen X, Peng J, Tan H, Qin Y, Peng Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115547
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115547
Design and synthesis of 3,4-seco-lupane triterpene derivatives to resist myocardial ischemia-reperfusion injury by inhibiting oxidative stress-mediated mitochondrial dysfunction via the PI3K/AKT/HIF-1α axis.
Teng H, Wu D, Lu L, Gao C, Wang H, Zhao Y, Wang L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115452
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115452
L-arabinose Attenuates LPS-Induced Intestinal Inflammation and Injury through Reduced M1 Macrophage Polarization.
Kang L, Pang J, Zhang X, Liu Y, Wu Y, Wang J, Han D
The Journal of nutrition 2023 Nov;153(11):3327-3340
The Journal of nutrition 2023 Nov;153(11):3327-3340
Meroterpenoids from Daphne genkwa shows promising in vitro antitumor activity via inhibiting PI3K/Akt/mTOR signaling pathway in A549 cells.
Ma RF, Liu H, Zhao XC, Shan P, Sun P, Xue JJ, Wei G, Zhang H
Bioorganic chemistry 2023 Nov;140:106803
Bioorganic chemistry 2023 Nov;140:106803
Effects of the PI3K/Akt/HO-1 pathway on autophagy in a sepsis-induced acute lung injury mouse model.
Tian J, Li Y, Mao X, Xie K, Zheng Y, Yu Y, Yu Y
International immunopharmacology 2023 Nov;124(Pt B):111063
International immunopharmacology 2023 Nov;124(Pt B):111063
E3 ubiquitin ligase Siah1 aggravates NAFLD through Scp2 ubiquitination.
Zhu Z, Hu X, Liu K, Li J, Fan K, Wang H, Wang L, He L, Ma Y, Guan R, Wang Z
International immunopharmacology 2023 Nov;124(Pt A):110897
International immunopharmacology 2023 Nov;124(Pt A):110897
Pachymic acid suppresses the inflammatory response of chondrocytes and alleviates the progression of osteoarthritis via regulating the Sirtuin 6/NF-κB signal axis.
Wu Y, Ying J, Zhu X, Xu C, Wu L
International immunopharmacology 2023 Nov;124(Pt A):110854
International immunopharmacology 2023 Nov;124(Pt A):110854
The STING inhibitor C-176 attenuates MPTP-induced neuroinflammation and neurodegeneration in mouse parkinsonian models.
Wang B, Wang Y, Qiu J, Gao S, Yu S, Sun D, Lou H
International immunopharmacology 2023 Nov;124(Pt A):110827
International immunopharmacology 2023 Nov;124(Pt A):110827
Human placental mesenchymal stromal cells modulate IFN-γ and IL-10 secretion by CD4(+)T cells via CD73, and alleviate intestinal damage in mice with graft-versus-host disease.
Zhang J, Zhao Y, Zhang H, Han K, Ma J, Xiong Y, Wang G, Luan X
International immunopharmacology 2023 Nov;124(Pt A):110767
International immunopharmacology 2023 Nov;124(Pt A):110767
Glycosides of Buyang Huanwu decoction inhibits pyroptosis associated with cerebral ischemia-reperfusion through Nrf2-mediated antioxidant signaling pathway both in vivo and in vitro.
She Y, Shao L, Jiao K, Sun R, Lang T, Long H, Tang Y, Zhang W, Ding C, Deng C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155001
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155001
Mesenchymal stem cell-derived exosomal miR-548x-3p inhibits pyroptosis of vascular endothelial cells through HMGB1 in heat stroke.
Pei Y, Ma W, Wang H, Chen F, Xiao W, Fan M, Han X, Cao Y
Genomics 2023 Nov;115(6):110719
Genomics 2023 Nov;115(6):110719
Inhibition of STAT-mediated cytokine responses to chemically-induced colitis prevents inflammation-associated neurobehavioral impairments.
Sin R, Sotogaku N, Ohnishi YN, Shuto T, Kuroiwa M, Kawahara Y, Sugiyama K, Murakami Y, Kanai M, Funakoshi H, Chakraborti A, Bibb JA, Nishi A
Brain, behavior, and immunity 2023 Nov;114:173-186
Brain, behavior, and immunity 2023 Nov;114:173-186
KLF5/MDM2 Axis Modulates Oxidative Stress and Epithelial-Mesenchymal Transition in Human Lens Epithelial Cells: The Role in Diabetic Cataract.
Li X, Chen D, Ouyang B, Wang S, Li Y, Li L, Zhu S, Zheng G
Laboratory investigation; a journal of technical methods and pathology 2023 Nov;103(11):100226
Laboratory investigation; a journal of technical methods and pathology 2023 Nov;103(11):100226
Guanxin V alleviates ventricular remodeling by promoting transforming growth factor-beta 1-mediated proteasomal degradation of Vimentin.
Gu N, Liang B
Poultry science 2023 Nov;102(11):103026
Poultry science 2023 Nov;102(11):103026
The Peptide AWRK6 Alleviates Lipid Accumulation in Hepatocytes by Inhibiting miR-5100 Targeting G6PC.
Liu J, Liu Y, Wang Q, Jin L, Zhang D
International journal of molecular sciences 2023 Nov 9;24(22)
International journal of molecular sciences 2023 Nov 9;24(22)
Aqueous Extract of Brassica rapa L.'s Impact on Modulating Exercise-Induced Fatigue via Gut-Muscle Axis.
Wang C, Zhu H, Cheng Y, Guo Y, Zhao Y, Qian H
Nutrients 2023 Nov 9;15(22)
Nutrients 2023 Nov 9;15(22)
Hyperoside Protects Trastuzumab-Induced Cardiotoxicity via Activating the PI3K/Akt Signaling Pathway.
Wei S, Ma W, Xie S, Liu S, Xie N, Li W, Zhang B, Liu J
Cardiovascular drugs and therapy 2023 Nov 9;
Cardiovascular drugs and therapy 2023 Nov 9;
Duck Tembusu virus induces incomplete autophagy via the ERK/mTOR and AMPK/mTOR signalling pathways to promote viral replication in neuronal cells.
Wang Q, Jiang Y, Bao G, Yao W, Yang Q, Chen S, Wang G
Veterinary research 2023 Nov 7;54(1):103
Veterinary research 2023 Nov 7;54(1):103
Bone marrow immune cells respond to fluctuating nutritional stress to constrain weight regain.
Zhou HY, Feng X, Wang LW, Zhou R, Sun H, Chen X, Lu RB, Huang Y, Guo Q, Luo XH
Cell metabolism 2023 Nov 7;35(11):1915-1930.e8
Cell metabolism 2023 Nov 7;35(11):1915-1930.e8
Cuproptosis-related gene DLAT serves as a prognostic biomarker for immunotherapy in clear cell renal cell carcinoma: multi-database and experimental verification.
Huang S, Cai C, Zhou K, Wang X, Wang X, Cen D, Weng G
Aging 2023 Nov 7;15(21):12314-12329
Aging 2023 Nov 7;15(21):12314-12329
An ULK1/2-PXN mechanotransduction pathway suppresses breast cancer cell migration.
Liang P, Zhang J, Wu Y, Zheng S, Xu Z, Yang S, Wang J, Ma S, Xiao L, Hu T, Jiang W, Huang C, Xing Q, Kundu M, Wang B
EMBO reports 2023 Nov 6;24(11):e56850
EMBO reports 2023 Nov 6;24(11):e56850
Chromofungin, a chromogranin A-derived peptide, protects against sepsis-induced acute lung injury by inhibiting LBP/TLR4-dependent inflammatory signaling.
Zhou W, Kang S, Wang F, Qin Y, Liu J, Xiao X, Chen X, Zhang D
European journal of pharmacology 2023 Nov 5;958:176043
European journal of pharmacology 2023 Nov 5;958:176043
Discovery of a novel dual-target inhibitor of CDK12 and PARP1 that induces synthetic lethality for treatment of triple-negative breast cancer.
Zhang L, Zhen Y, Feng L, Li Z, Lu Y, Wang G, Ouyang L
European journal of medicinal chemistry 2023 Nov 5;259:115648
European journal of medicinal chemistry 2023 Nov 5;259:115648
Cell volume controlled by LRRC8A-formed volume-regulated anion channels fine-tunes T cell activation and function.
Wang Y, Sun Z, Ping J, Tang J, He B, Chang T, Zhou Q, Yuan S, Tang Z, Li X, Lu Y, He R, He X, Liu Z, Yin L, Wu N
Nature communications 2023 Nov 4;14(1):7075
Nature communications 2023 Nov 4;14(1):7075
PGAM5 degrades PDCoV N protein and activates type I interferon to antagonize viral replication.
Yang X, Kong N, Qin W, Zhai X, Song Y, Tong W, Li L, Liu C, Zheng H, Yu H, Zhang W, Tong G, Shan T
Journal of virology 2023 Nov 30;97(11):e0147023
Journal of virology 2023 Nov 30;97(11):e0147023
Alphavirus-based replicons demonstrate different interactions with host cells and can be optimized to increase protein expression.
Dominguez F, Palchevska O, Frolova EI, Frolov I
Journal of virology 2023 Nov 30;97(11):e0122523
Journal of virology 2023 Nov 30;97(11):e0122523
Jun-APOE-LRP1 axis promotes tumor metastasis in colorectal cancer.
He L, Shi M, Ren S, Zhang J, Tian Y, Yang X, Liu H
Biomolecules & biomedicine 2023 Nov 3;23(6):1026-1037
Biomolecules & biomedicine 2023 Nov 3;23(6):1026-1037
Selective activator of human ClpP triggers cell cycle arrest to inhibit lung squamous cell carcinoma.
Zhou LL, Zhang T, Xue Y, Yue C, Pan Y, Wang P, Yang T, Li M, Zhou H, Ding K, Gan J, Ji H, Yang CG
Nature communications 2023 Nov 3;14(1):7069
Nature communications 2023 Nov 3;14(1):7069
Spliceosome component Usp39 contributes to hepatic lipid homeostasis through the regulation of autophagy.
Cui D, Wang Z, Dang Q, Wang J, Qin J, Song J, Zhai X, Zhou Y, Zhao L, Lu G, Liu H, Liu G, Liu R, Shao C, Zhang X, Liu Z
Nature communications 2023 Nov 3;14(1):7032
Nature communications 2023 Nov 3;14(1):7032
A bacteria-derived tetramerized protein ameliorates nonalcoholic steatohepatitis in mice via binding and relocating acetyl-coA carboxylase.
Lin Y, Yang M, Huang L, Yang F, Fan J, Qiang Y, Chang Y, Zhou W, Yan L, Xiong J, Ping J, Chen S, Men D, Li F
Cell reports 2023 Nov 28;42(11):113453
Cell reports 2023 Nov 28;42(11):113453
Targeting PRMT1-mediated SRSF1 methylation to suppress oncogenic exon inclusion events and breast tumorigenesis.
Li WJ, Huang Y, Lin YA, Zhang BD, Li MY, Zou YQ, Hu GS, He YH, Yang JJ, Xie BL, Huang HH, Deng X, Liu W
Cell reports 2023 Nov 28;42(11):113385
Cell reports 2023 Nov 28;42(11):113385
Kaempferol Improves Breast Cancer-Related Depression through the COX-2/PGE2 Pathway.
Zhu Q, Han Y, He Y, Fu Y, Yang H, Chen Y, Shi Y
Frontiers in bioscience (Landmark edition) 2023 Nov 28;28(11):311
Frontiers in bioscience (Landmark edition) 2023 Nov 28;28(11):311
A Mild Hyperthermia Hollow Carbon Nanozyme as Pyroptosis Inducer for Boosted Antitumor Immunity.
Tao N, Jiao L, Li H, Deng L, Wang W, Zhao S, Chen W, Chen L, Zhu C, Liu YN
ACS nano 2023 Nov 28;17(22):22844-22858
ACS nano 2023 Nov 28;17(22):22844-22858
LSM14B is essential for oocyte meiotic maturation by regulating maternal mRNA storage and clearance.
Wan Y, Yang S, Li T, Cai Y, Wu X, Zhang M, Muhammad T, Huang T, Lv Y, Chan WY, Lu G, Li J, Sha QQ, Chen ZJ, Liu H
Nucleic acids research 2023 Nov 27;51(21):11652-11667
Nucleic acids research 2023 Nov 27;51(21):11652-11667
FUNDC2, a mitochondrial outer membrane protein, mediates triple-negative breast cancer progression via the AKT/GSK3β/GLI1 pathway.
Yin L, Cao R, Liu Z, Luo G, Li Y, Zhou X, Chen X, Wu Y, He J, Zu X, Shen Y
Acta biochimica et biophysica Sinica 2023 Nov 25;55(11):1770-1783
Acta biochimica et biophysica Sinica 2023 Nov 25;55(11):1770-1783
Intervention of Tanshinone IIA on the PGK1-PDHK1 Pathway to Reprogram Macrophage Phenotype After Myocardial Infarction.
Gao S, Yang Z, Li D, Wang B, Zheng X, Li C, Fan G
Cardiovascular drugs and therapy 2023 Nov 22;
Cardiovascular drugs and therapy 2023 Nov 22;
The Protective Effects of Reineckia carnea Ether Fraction against Alzheimer's Disease Pathology: An Exploration in Caenorhabditis elegans Models.
Fu HJ, Zhou XY, Li YP, Chen X, He YN, Qin DL, Yu L, Yu CL, Wu JM, Wu AG, Zhou XG
International journal of molecular sciences 2023 Nov 20;24(22)
International journal of molecular sciences 2023 Nov 20;24(22)
RGS5 maintaining vascular homeostasis is altered by the tumor microenvironment.
Kong P, Wang X, Gao YK, Zhang DD, Huang XF, Song Y, Zhang WD, Guo RJ, Li H, Han M
Biology direct 2023 Nov 20;18(1):78
Biology direct 2023 Nov 20;18(1):78
Progesterone Activates the Histone Lactylation-Hif1α-glycolysis Feedback Loop to Promote Decidualization.
Zhao W, Wang Y, Liu J, Yang Q, Zhang S, Hu X, Shi Z, Zhang Z, Tian J, Chu D, An L
Endocrinology 2023 Nov 20;165(1)
Endocrinology 2023 Nov 20;165(1)
Attenuation of estrogen and its receptors in the post-menopausal stage exacerbates dyslipidemia and leads to cognitive impairment.
Meng Q, Chao Y, Zhang S, Ding X, Feng H, Zhang C, Liu B, Zhu W, Li Y, Zhang Q, Tong H, Wu L, Bian H
Molecular brain 2023 Nov 20;16(1):80
Molecular brain 2023 Nov 20;16(1):80
Cinnamaldehyde Alleviates Bone Loss by Targeting Oxidative Stress and Mitochondrial Damage via the Nrf2/HO-1 Pathway in BMSCs and Ovariectomized Mice.
Lin BH, Ma RX, Wu JT, Du SQ, Lv YY, Yu HN, Zhang W, Mao SM, Liu GY, Bu YT, Chen ZH, Jin C, Wu ZY, Yang L
Journal of agricultural and food chemistry 2023 Nov 2;
Journal of agricultural and food chemistry 2023 Nov 2;
Iron derived from NCOA4-mediated ferritinophagy causes cellular senescence via the cGAS-STING pathway.
Li HY, Wei TT, Zhuang M, Tan CY, Xie TH, Cai J, Yao Y, Zhu L
Cell death discovery 2023 Nov 18;9(1):419
Cell death discovery 2023 Nov 18;9(1):419
Ferroptosis sensitization in glioma: exploring the regulatory mechanism of SOAT1 and its therapeutic implications.
Sun S, Qi G, Chen H, He D, Ma D, Bie Y, Xu L, Feng B, Pang Q, Guo H, Zhang R
Cell death & disease 2023 Nov 18;14(11):754
Cell death & disease 2023 Nov 18;14(11):754
ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury.
Zhang Y, Fan Y, Hu H, Zhang X, Wang Z, Wu Z, Wang L, Yu X, Song X, Xiang P, Zhang X, Wang T, Tan S, Li C, Gao L, Liang X, Li S, Li N, Yue X, Ma C
Nature communications 2023 Nov 18;14(1):7527
Nature communications 2023 Nov 18;14(1):7527
DLX2 promotes osteosarcoma epithelial-mesenchymal transition and doxorubicin resistance by enhancing HOXC8-CDH2 axis.
Zhang B, Du X, Fan Y, Qu G, Pang LK, Zhao R, Yao W
iScience 2023 Nov 17;26(11):108272
iScience 2023 Nov 17;26(11):108272
AKAP150 from nucleus accumbens dopamine D1 and D2 receptor-expressing medium spiny neurons regulates morphine withdrawal.
Bai X, Zhang K, Ou C, Mu Y, Chi D, Zhang J, Huang J, Li X, Zhang Y, Huang W, Ouyang H
iScience 2023 Nov 17;26(11):108227
iScience 2023 Nov 17;26(11):108227
Cullin 5 aggravates hypoxic pulmonary hypertension by activating TRAF6/NF-κB/HIF-1α/VEGF.
Wang L, Huang J, Zhang R, Zhang M, Guo Y, Liu Y, Li C, Wang W, Ying S, Liu J, Wang C
iScience 2023 Nov 17;26(11):108199
iScience 2023 Nov 17;26(11):108199
Oral pathogens exacerbate Parkinson's disease by promoting Th1 cell infiltration in mice.
Bai XB, Xu S, Zhou LJ, Meng XQ, Li YL, Chen YL, Jiang YH, Lin WZ, Chen BY, Du LJ, Tian GC, Liu Y, Duan SZ, Zhu YQ
Microbiome 2023 Nov 17;11(1):254
Microbiome 2023 Nov 17;11(1):254
Blockage of CacyBP inhibits macrophage recruitment and improves anti-PD-1 therapy in hepatocellular carcinoma.
Wang J, Zhang X, Ma X, Chen D, Cai M, Xiao L, Li J, Huang Z, Huang Y, Lian Y
Journal of experimental & clinical cancer research : CR 2023 Nov 16;42(1):303
Journal of experimental & clinical cancer research : CR 2023 Nov 16;42(1):303
Simvastatin induces pyroptosis via ROS/caspase-1/GSDMD pathway in colon cancer.
Xie W, Peng M, Liu Y, Zhang B, Yi L, Long Y
Cell communication and signaling : CCS 2023 Nov 16;21(1):329
Cell communication and signaling : CCS 2023 Nov 16;21(1):329
Development of decoy oligonucleotide-warheaded chimeric molecules targeting STAT3.
Shih PC, Naganuma M, Tsuji G, Demizu Y, Naito M
Bioorganic & medicinal chemistry 2023 Nov 15;95:117507
Bioorganic & medicinal chemistry 2023 Nov 15;95:117507
Structural determinants specific for retromer protein sorting nexin 5 in regulating subcellular retrograde membrane trafficking.
Chen Q, Sun M, Han X, Xu H, Liu Y
Journal of biomedical research 2023 Nov 15;37(6):492-506
Journal of biomedical research 2023 Nov 15;37(6):492-506
Inhibition of METTL3 alleviated LPS-induced alveolar epithelial cell apoptosis and acute lung injury via restoring neprilysin expression.
Jia J, Yuan Y, He Y, Wasti B, Duan W, Chen Z, Li D, Sun W, Zeng Q, Ma L, Zhang X, Liu S, Zhang D, Liu L, Liu Q, Liang H, Wang G, Xiang X, Xiao B
Life sciences 2023 Nov 15;333:122148
Life sciences 2023 Nov 15;333:122148
Discovery of potent pyrrolo-pyrimidine and purine HDAC inhibitors for the treatment of advanced prostate cancer.
Moi D, Bonanni D, Belluti S, Linciano P, Citarella A, Franchini S, Sorbi C, Imbriano C, Pinzi L, Rastelli G
European journal of medicinal chemistry 2023 Nov 15;260:115730
European journal of medicinal chemistry 2023 Nov 15;260:115730
Sclerotome-derived PDGF signaling functions as a niche cue responsible for primitive erythropoiesis.
Mao A, Li Z, Ning G, Zhou Z, Wei C, Li J, He X, Wang Q
Development (Cambridge, England) 2023 Nov 15;150(22)
Development (Cambridge, England) 2023 Nov 15;150(22)
Polyamine metabolism controls B-to-Z DNA transition to orchestrate DNA sensor cGAS activity.
Zhao C, Ma Y, Zhang M, Gao X, Liang W, Qin Y, Fu Y, Jia M, Song H, Gao C, Zhao W
Immunity 2023 Nov 14;56(11):2508-2522.e6
Immunity 2023 Nov 14;56(11):2508-2522.e6
Interactome profiling of Crimean-Congo hemorrhagic fever virus glycoproteins.
Dai S, Min YQ, Li Q, Feng K, Jiang Z, Wang Z, Zhang C, Ren F, Fang Y, Zhang J, Zhu Q, Wang M, Wang H, Deng F, Ning YJ
Nature communications 2023 Nov 14;14(1):7365
Nature communications 2023 Nov 14;14(1):7365
The hippocampal FTO-BDNF-TrkB pathway is required for novel object recognition memory reconsolidation in mice.
Chang R, Zhu S, Peng J, Lang Z, Zhou X, Liao H, Zou J, Zeng P, Tan S
Translational psychiatry 2023 Nov 14;13(1):349
Translational psychiatry 2023 Nov 14;13(1):349
Curcumin enhances elvitegravir concentration and alleviates oxidative stress and inflammatory response.
Godse S, Zhou L, Sinha N, Kodidela S, Kumar A, Singh UP, Kumar S
Scientific reports 2023 Nov 14;13(1):19864
Scientific reports 2023 Nov 14;13(1):19864
Ubc9 regulates the expression of MHC II in dendritic cells to enhance DSS-induced colitis by mediating RBPJ SUMOylation.
Zhang J, Chen L, Xu Q, Zou Y, Sun F, Zhou Q, Luo X, Li Y, Chen C, Zhang S, Xiong F, Yang P, Liu S, Wang CY
Cell death & disease 2023 Nov 13;14(11):737
Cell death & disease 2023 Nov 13;14(11):737
Identification of OLA1 as a Novel Protein Target of Vitexin to Ameliorate Dextran Sulfate Sodium-Induced Colitis with Tissue Thermal Proteome Profiling.
Li N, Wang R, Li W, Du Q, Deng Z, Fan Y, Zheng L
Journal of agricultural and food chemistry 2023 Nov 1;71(43):16057-16066
Journal of agricultural and food chemistry 2023 Nov 1;71(43):16057-16066
Phlorizin Mitigates Dextran Sulfate Sodium-Induced Colitis in Mice by Modulating Gut Microbiota and Inhibiting Ferroptosis.
Cheng J, Liu D, Huang Y, Chen L, Li Y, Yang Z, Fu S, Hu G
Journal of agricultural and food chemistry 2023 Nov 1;71(43):16043-16056
Journal of agricultural and food chemistry 2023 Nov 1;71(43):16043-16056
Col3a1 delivered via extracellular vesicles of Sertoli cells is essential for mice Sertoli cell proliferation.
Zhu Y, Lin Y, Zheng X, Wang H, Li Z, Sun F
Molecular and cellular endocrinology 2023 Nov 1;577:112036
Molecular and cellular endocrinology 2023 Nov 1;577:112036
Oncogene SCARNA12 as a potential diagnostic biomarker for colorectal cancer.
Zhang H, Liu X, Zhang W, Deng J, Lin C, Qi Z, Li Y, Gu Y, Wang Q, Shen L, Wang Z
Molecular biomedicine 2023 Nov 1;4(1):37
Molecular biomedicine 2023 Nov 1;4(1):37
Genome-Wide CRISPR/Cas9 Screening Identifies That Mitochondrial Solute Carrier SLC25A23 Attenuates Type I IFN Antiviral Immunity via Interfering with MAVS Aggregation.
Zhang H, Li X, Wang Y, Liu X, Guo J, Wang Z, Zhang L, Xiong S, Dong C
Journal of immunology (Baltimore, Md. : 1950) 2023 Nov 1;211(9):1406-1417
Journal of immunology (Baltimore, Md. : 1950) 2023 Nov 1;211(9):1406-1417
Soluble epoxide hydrolase deficiency attenuates airway inflammation in COPD via IRE1α/JNK/AP-1 signaling pathway.
Yu Y, Yang A, He X, Wu B, Wu Y, Li Y, Nie S, Xu B, Wang H, Yu G
Journal of inflammation (London, England) 2023 Nov 1;20(1):36
Journal of inflammation (London, England) 2023 Nov 1;20(1):36
Follicle-stimulating hormone orchestrates glucose-stimulated insulin secretion of pancreatic islets.
Cheng Y, Zhu H, Ren J, Wu HY, Yu JE, Jin LY, Pang HY, Pan HT, Luo SS, Yan J, Dong KX, Ye LY, Zhou CL, Pan JX, Meng ZX, Yu T, Jin L, Lin XH, Wu YT, Yang HB, Liu XM, Sheng JZ, Ding GL, Huang HF
Nature communications 2023 Nov 1;14(1):6991
Nature communications 2023 Nov 1;14(1):6991
A human mitofusin 2 mutation can cause mitophagic cardiomyopathy.
Franco A, Li J, Kelly DP, Hershberger RE, Marian AJ, Lewis RM, Song M, Dang X, Schmidt AD, Mathyer ME, Edwards JR, Strong CG, Dorn GW
eLife 2023 Nov 1;12
eLife 2023 Nov 1;12
Photobiomodulation augments the effects of mitochondrial transplantation in the treatment of spinal cord injury in rats by facilitating mitochondrial transfer to neurons via Connexin 36.
Zhu Z, Li X, Wang X, Zuo X, Ma Y, Gao X, Liang Z, Zhang Z, Song Z, Ding T, Ju C, Li P, Li K, Zhang J, Quan H, Wang Z, Hu X
Bioengineering & translational medicine 2023 May;8(3):e10473
Bioengineering & translational medicine 2023 May;8(3):e10473
Triptolide injection reduces Alzheimer's disease-like pathology in mice.
Mao R, Xu S, Sun G, Yu Y, Zuo Z, Wang Y, Yang K, Zhang Z, Yang W
Synapse (New York, N.Y.) 2023 May;77(3):e22261
Synapse (New York, N.Y.) 2023 May;77(3):e22261
GSTP1-mediated S-glutathionylation of Pik3r1 is a redox hub that inhibits osteoclastogenesis through regulating autophagic flux.
Ji X, Hong J, Yang W, Yao M, Wang J, Jiang G, Wang Y, Li C, Lin J, Mou H, Li C, Li S, Chen Y, Shi M, Wang W, Lu F, Wu H, Zhao X, Qi Y, Yan S
Redox biology 2023 May;61:102635
Redox biology 2023 May;61:102635
Relationship between IL-22 and IL-22BP in diabetic cognitive dysfunction.
Wang X, Yu S, Liu W, Lv P, Zhao L, Wang Y, Fu C, Meng L, Yang Q, Wang X, Huang Y, Zuo Z, Liu X
Acta diabetologica 2023 May;60(5):631-644
Acta diabetologica 2023 May;60(5):631-644
Segregation of pathways leading to pexophagy.
Barone FG, Urbé S, Clague MJ
Life science alliance 2023 May;6(5)
Life science alliance 2023 May;6(5)
MSC-EXO and tempol ameliorate bronchopulmonary dysplasia in newborn rats by activating HIF-1α.
Wang J, Zhang A, Huang F, Xu J, Zhao M
Pediatric pulmonology 2023 May;58(5):1367-1379
Pediatric pulmonology 2023 May;58(5):1367-1379
Cannabinoid type 2 receptor activation inhibits MPP(+)-induced M1 differentiation of microglia through activating PI3K/Akt/Nrf2 signal pathway.
Wang M, Liu M, Ma Z
Molecular biology reports 2023 May;50(5):4423-4433
Molecular biology reports 2023 May;50(5):4423-4433
Discovery of a natural small-molecule AMP-activated kinase activator that alleviates nonalcoholic steatohepatitis.
Chen J, Xu L, Zhang XQ, Liu X, Zhang ZX, Zhu QM, Liu JY, Iqbal MO, Ding N, Shao CL, Wei MY, Gu YC
Marine life science & technology 2023 May;5(2):196-210
Marine life science & technology 2023 May;5(2):196-210
Apelin-13 Improves Cognitive Impairment and Repairs Hippocampal Neuronal Damage by Activating PGC-1α/PPARγ Signaling.
Chen B, Wu J, Hu S, Liu Q, Yang H, You Y
Neurochemical research 2023 May;48(5):1504-1515
Neurochemical research 2023 May;48(5):1504-1515
TRPM8 promotes hepatocellular carcinoma progression by inducing SNORA55 mediated nuclear-mitochondrial communication.
Fu J, Liu G, Zhang X, Lei X, Liu Q, Qian K, Tong Q, Qin W, Li Z, Cao Z, Zhang J, Liu C, Wang Z, Liu Z, Liang XM, Yamamoto H, Xu X
Cancer gene therapy 2023 May;30(5):738-751
Cancer gene therapy 2023 May;30(5):738-751
PKM2 allosteric converter: A self-assembly peptide for suppressing renal cell carcinoma and sensitizing chemotherapy.
Wang L, Fu B, Hou DY, Lv YL, Yang G, Li C, Shen JC, Kong B, Zheng LB, Qiu Y, Wang HL, Liu C, Zhang JJ, Bai SY, Li LL, Wang H, Xu WH
Biomaterials 2023 May;296:122060
Biomaterials 2023 May;296:122060
Staphylococcus aureus induces mitophagy to promote its survival within bovine mammary epithelial cells.
Xu D, Hu G, Luo J, Cheng J, Wu D, Cheng L, Huang X, Fu S, Liu J
Veterinary microbiology 2023 May;280:109697
Veterinary microbiology 2023 May;280:109697
CD98 regulates the phosphorylation of HER2 and a bispecific anti-HER2/CD98 antibody inhibits the growth signal of human breast cancer cells.
Yamasaki A, Maruyama-Takahashi K, Nishida K, Okazaki S, Okita K, Akiyama Y, Suzuki H, Endo Y, Masuko K, Masuko T, Tomioka Y
Genes to cells : devoted to molecular & cellular mechanisms 2023 May;28(5):374-382
Genes to cells : devoted to molecular & cellular mechanisms 2023 May;28(5):374-382
Curcumin protects against doxorubicin induced oxidative stress by regulating the Keap1-Nrf2-ARE and autophagy signaling pathways.
Liao D, Shangguan D, Wu Y, Chen Y, Liu N, Tang J, Yao D, Shi Y
Psychopharmacology 2023 May;240(5):1179-1190
Psychopharmacology 2023 May;240(5):1179-1190
Lipid phosphatase SAC1 suppresses hepatitis B virus replication through promoting autophagic degradation of virions.
Zheng J, Deng Y, Wei Z, Zou H, Wen X, Cai J, Zhang S, Jia B, Lu M, Lu K, Lin Y
Antiviral research 2023 May;213:105601
Antiviral research 2023 May;213:105601
HIF-1α Mediates Arsenic-Induced Metabolic Reprogramming in Lung Bronchial Epithelial Cells.
Wang W, Zhang A
Biological trace element research 2023 May;201(5):2284-2293
Biological trace element research 2023 May;201(5):2284-2293
Proline promotes proliferation and drug resistance of multiple myeloma by downregulation of proline dehydrogenase.
Zhang J, Shi F, Liu X, Wu X, Hu C, Guo J, Yang Q, Xia J, He Y, An G, Qiu L, Feng X, Zhou W
British journal of haematology 2023 May;201(4):704-717
British journal of haematology 2023 May;201(4):704-717
Themis suppresses the effector function of CD8(+) T cells in acute viral infection.
Tang J, Jia X, Li J, Dong J, Wang J, Li W, Zhu Y, Hu Y, Hou B, Lin C, Cong Y, Ren T, Yan C, Yang H, Lai Q, Zheng H, Bao Y, Gautam N, Wang HR, Xu B, Chen XL, Li Q, Gascoigne NRJ, Fu G
Cellular & molecular immunology 2023 May;20(5):512-524
Cellular & molecular immunology 2023 May;20(5):512-524
Novel secreted STPKLRR from Vibrio splendidus AJ01 promotes pathogen internalization via mediating tropomodulin phosphorylation dependent cytoskeleton rearrangement.
Dai F, Guo M, Shao Y, Li C
PLoS pathogens 2023 May;19(5):e1011419
PLoS pathogens 2023 May;19(5):e1011419
EphA2 is a functional entry receptor for HCMV infection of glioblastoma cells.
Dong XD, Li Y, Li Y, Sun C, Liu SX, Duan H, Cui R, Zhong Q, Mou YG, Wen L, Yang B, Zeng MS, Luo MH, Zhang H
PLoS pathogens 2023 May;19(5):e1011304
PLoS pathogens 2023 May;19(5):e1011304
Bisphenol P exposure in C57BL/6 mice caused gut microbiota dysbiosis and induced intestinal barrier disruption via LPS/TLR4/NF-κB signaling pathway.
Ma N, Ma D, Liu X, Zhao L, Ma L, Ma D, Dong S
Environment international 2023 May;175:107949
Environment international 2023 May;175:107949
CDGSH iron sulfur domain 2 over-expression alleviates neuronal ferroptosis and brain injury by inhibiting lipid peroxidation via AKT/mTOR pathway following intracerebral hemorrhage in mice.
Li R, Zhang X, Gu L, Yuan Y, Luo X, Shen W, Xie Z
Journal of neurochemistry 2023 May;165(3):426-444
Journal of neurochemistry 2023 May;165(3):426-444
Targeting ZDHHC9 potentiates anti-programmed death-ligand 1 immunotherapy of pancreatic cancer by modifying the tumor microenvironment.
Lin Z, Huang K, Guo H, Jia M, Sun Q, Chen X, Wu J, Yao Q, Zhang P, Vakal S, Zou Z, Gao H, Ci L, Chen J, Guo W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114567
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114567
CBL0137 activates ROS/BAX signaling to promote caspase-3/GSDME-dependent pyroptosis in ovarian cancer cells.
Yang C, Wang ZQ, Zhang ZC, Lou G, Jin WL
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114529
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114529
The impact and mechanism of TET3 overexpression on the progression of hepatic fibrosis.
Liu R, Feng L, Tang S, Liu Y, Yang Q
Epigenomics 2023 May;15(10):577-591
Epigenomics 2023 May;15(10):577-591
Characterization and mechanisms of radioresistant lung squamous cell carcinoma cell lines.
Pan L, Wu Q, Wang Y, Ma S, Zhang S
Thoracic cancer 2023 May;14(14):1239-1250
Thoracic cancer 2023 May;14(14):1239-1250
High-frequency repetitive transcranial magnetic stimulation protects against cerebral ischemia/reperfusion injury in rats: Involving the mitigation of ferroptosis and inflammation.
Zhou GJ, Liu DN, Huang XR, Wu Q, Feng WB, Zeng YH, Liu HY, Yu J, Xiao ZJ, Zhou J
Brain and behavior 2023 May;13(5):e2988
Brain and behavior 2023 May;13(5):e2988
NSUN2-mediated m(5) C RNA methylation dictates retinoblastoma progression through promoting PFAS mRNA stability and expression.
Zuo S, Li L, Wen X, Gu X, Zhuang A, Li R, Ye F, Ge S, Fan X, Fan J, Chai P, Lu L
Clinical and translational medicine 2023 May;13(5):e1273
Clinical and translational medicine 2023 May;13(5):e1273
Integrating HPLC-Q-TOF-MS/MS, network pharmacology and experimental validation to decipher the chemical substances and mechanism of modified Gui-shao-liu-jun-zi decoction against gastric cancer.
Huang W, Wen F, Ruan S, Gu P, Gu S, Song S, Zhou J, Li Y, Liu J, Shu P
Journal of traditional and complementary medicine 2023 May;13(3):245-262
Journal of traditional and complementary medicine 2023 May;13(3):245-262
Extracellular vesicles derived from Akkermansia muciniphila promote placentation and mitigate preeclampsia in a mouse model.
Chen Y, Ou Z, Pang M, Tao Z, Zheng X, Huang Z, Wen D, Li Q, Zhou R, Chen P, Situ B, Sheng C, Huang Y, Yue X, Zheng L, Huang L
Journal of extracellular vesicles 2023 May;12(5):e12328
Journal of extracellular vesicles 2023 May;12(5):e12328
d-mannose blocks the interaction between keratinocytes and Th17 cells to alleviate psoriasis by inhibiting HIF-1α/CCL20 in mice.
Jiang Q, Wei B, You M, Zhou X
International immunopharmacology 2023 May;118:110087
International immunopharmacology 2023 May;118:110087
Tanshinone IIA analogue 15a inhibits NLRP3-mediated inflammation by activating mitophagy in macrophages to alleviate acute tubular necrosis.
Chen J, Luo W, Hu C, Ren M, Xu H, Xu X, Li W, Chen Y, Shao J, Xiao Z, Lv X, Liang G
International immunopharmacology 2023 May;118:110065
International immunopharmacology 2023 May;118:110065
C1q/tumor necrosis factor-related protein-9 exerts antioxidant and anti-inflammatory effects on oxygen-glucose deprivation/reoxygenation-stimulated neurons by modulating the Akt-GSK-3β-Nrf2 cascade via AdipoR1.
Wang J, Ren B, Yang Y, Li Y
International immunopharmacology 2023 May;118:110045
International immunopharmacology 2023 May;118:110045
Highly pathogenic porcine reproductive and respiratory syndrome virus-induced inflammatory response in porcine pulmonary microvascular endothelial cells and effects of herbal ingredients on main inflammatory molecules.
Wu Y, Song X, Li P, Wang Z, Zhao Z, Zhang T
International immunopharmacology 2023 May;118:110012
International immunopharmacology 2023 May;118:110012
Prognosis-related VDAC1 regulates the proliferation and apoptosis of osteosarcoma cells via the MAPK signaling pathway.
Cai X, Zhu S
Genomics 2023 May;115(3):110595
Genomics 2023 May;115(3):110595
Loureirin C inhibits ferroptosis after cerebral ischemia reperfusion through regulation of the Nrf2 pathway in mice.
Liu Y, Mi Y, Wang Y, Meng Q, Xu L, Liu Y, Zhou D, Wang Y, Liang D, Li W, Li N, Hou Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 May;113:154729
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 May;113:154729
Rs15285, a functional polymorphism located in lipoprotein lipase, predicts the risk and prognosis of gastric cancer.
Shen K, Zhou X, Hu L, Xiao J, Cheng Q, Wang Y, Liu K, Fan H, Xu Z, Yang L
Applied microbiology and biotechnology 2023 May;107(10):3243-3256
Applied microbiology and biotechnology 2023 May;107(10):3243-3256
Orai1 is an Entotic Ca(2+) Channel for Non-Apoptotic Cell Death, Entosis in Cancer Development.
Lee AR, Park CY
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 May;10(14):e2205913
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 May;10(14):e2205913
Astaxanthin protects human ARPE-19 retinal pigment epithelium cells from blue light-induced phototoxicity by scavenging singlet oxygen.
Kitao M, Yamaguchi A, Tomioka T, Kai K, Kamei Y, Sugimoto K, Akagawa M
Free radical research 2023 May-Jun;57(6-12):430-443
Free radical research 2023 May-Jun;57(6-12):430-443
Resistance to anti-HER2 therapy associated with the TSC2 nonsynonymous variant c.4349 C > G (p.Pro1450Arg) is reversed by CDK4/6 inhibitor in HER2-positive breast cancer.
Yang Z, Feng J, Jing J, Huang Y, Ye WW, Lei L, Wang XJ, Cao WM
NPJ breast cancer 2023 May 9;9(1):36
NPJ breast cancer 2023 May 9;9(1):36
ER-localized JmjC domain-containing protein JMJD8 targets STING to promote immune evasion and tumor growth in breast cancer.
Yi J, Wang L, Du J, Wang M, Shen H, Liu Z, Qin Y, Liu J, Hu G, Xiao R, Ding J, Chen X, Wang H, Huang H, Ouyang G, Liu W
Developmental cell 2023 May 8;58(9):760-778.e6
Developmental cell 2023 May 8;58(9):760-778.e6
The relationship between gut microbiota and susceptibility to type 2 diabetes mellitus in rats.
An Y, Dai H, Duan Y, Cheng L, Shi L, He C, Wang C, Lv Y, Li H, Zhang H, Huang Y, Fu W, Sun W, Zhao B
Chinese medicine 2023 May 5;18(1):49
Chinese medicine 2023 May 5;18(1):49
The Screening of Broadly Neutralizing Antibodies Targeting the SARS-CoV-2 Spike Protein by mRNA Immunization in Mice.
An Z, Zhang Y, Yu X, Xia J, Yin Y, Li G, Lu J, Fan X, Xu Y
Pharmaceutics 2023 May 5;15(5)
Pharmaceutics 2023 May 5;15(5)
Mitochondrial Glycerol-3-Phosphate Dehydrogenase Restricts HBV Replication via the TRIM28-Mediated Degradation of HBx.
Liu C, Zhao K, Chen Y, Yao Y, Tang J, Wang J, Xu C, Yang Q, Zheng Y, Yuan Y, Sun H, Zhang Y, Zhou Y, Chen J, Wang Y, Wu C, Pei R, Chen X
Journal of virology 2023 May 31;97(5):e0058023
Journal of virology 2023 May 31;97(5):e0058023
Pancreatic tumors exhibit myeloid-driven amino acid stress and upregulate arginine biosynthesis.
Apiz Saab JJ, Dzierozynski LN, Jonker PB, AminiTabrizi R, Shah H, Menjivar RE, Scott AJ, Nwosu ZC, Zhu Z, Chen RN, Oh M, Sheehan C, Wahl DR, Pasca di Magliano M, Lyssiotis CA, Macleod KF, Weber CR, Muir A
eLife 2023 May 31;12
eLife 2023 May 31;12
Epsin1-mediated exosomal sorting of Dll4 modulates the tubular-macrophage crosstalk in diabetic nephropathy.
Liu JL, Zhang L, Huang Y, Li XH, Liu YF, Zhang SM, Zhao YE, Chen XJ, Liu Y, He LY, Dong Z, Liu FY, Sun L, Xiao L
Molecular therapy : the journal of the American Society of Gene Therapy 2023 May 3;31(5):1451-1467
Molecular therapy : the journal of the American Society of Gene Therapy 2023 May 3;31(5):1451-1467
Targeting copper death genotyping associated gene RARRES2 suppresses glioblastoma progression and macrophages infiltration.
Yan T, Yang H, Meng Y, Li H, Jiang Q, Liu J, Xu C, Xue Y, Xu J, Song Y, Chu X, Wang L, Chen X, Che F
Cancer cell international 2023 May 29;23(1):105
Cancer cell international 2023 May 29;23(1):105
Pulsatilla Decoction and its bioactive component β-peltatin induce G2/M cell cycle arrest and apoptosis in pancreatic cancer.
Wu R, Xi Z, Liu M, Ren H, Dai R, Jiang X, Nik Nabil WN, Wang Y, Feng J, Chai Q, Dong Q, Xu H
Chinese medicine 2023 May 28;18(1):61
Chinese medicine 2023 May 28;18(1):61
Anti-Neuroinflammatory Meroterpenoids from a Chinese Collection of the Brown Alga Sargassum siliquastrum.
Qi Y, Wang Z, Zhang J, Tang S, Zhu H, Jiang B, Li X, Wang J, Sun Z, Zhao M, Zhu H, Yan P
Journal of natural products 2023 May 26;86(5):1284-1293
Journal of natural products 2023 May 26;86(5):1284-1293
The Nrf2/HMGB1/NF-κB axis modulates chondrocyte apoptosis and extracellular matrix degradation in osteoarthritis.
Li W, Tao C, Mao M, Zhu K
Acta biochimica et biophysica Sinica 2023 May 26;55(5):818-830
Acta biochimica et biophysica Sinica 2023 May 26;55(5):818-830
Apolipoprotein A4 Elevates Sympathetic Activity and Thermogenesis in Male Mice.
Kuo HN, LaRussa Z, Xu FM, West K, Consitt L, Davidson WS, Liu M, Coschigano KT, Shi H, Lo CC
Nutrients 2023 May 26;15(11)
Nutrients 2023 May 26;15(11)
High Level of GMFG Correlated to Poor Clinical Outcome and Promoted Cell Migration and Invasion through EMT Pathway in Triple-Negative Breast Cancer.
Zhao Y, Wei X, Li J, Diao Y, Shan C, Li W, Zhang S, Wu F
Genes 2023 May 26;14(6)
Genes 2023 May 26;14(6)
miR-199a-5p from bone marrow mesenchymal stem cell exosomes promotes the proliferation of neural stem cells by targeting GSK-3β.
Yang Y, Li Y, Zhang S, Cao L, Zhang Y, Fang B
Acta biochimica et biophysica Sinica 2023 May 25;55(5):783-794
Acta biochimica et biophysica Sinica 2023 May 25;55(5):783-794
Rhein Inhibited Ferroptosis and EMT to Attenuate Diabetic Nephropathy by Regulating the Rac1/NOX1/β-Catenin Axis.
Xiong D, Hu W, Han X, Cai Y
Frontiers in bioscience (Landmark edition) 2023 May 25;28(5):100
Frontiers in bioscience (Landmark edition) 2023 May 25;28(5):100
The FBXO32/ATR/ATM axis acts as a molecular switch to control the sensitivity of osteosarcoma cells to irradiation through its regulation of EXO1 expression.
Lu Y, Huang P, Li Y, Liu W, Li J, Zhao R, Feng H, Shi C, Cao G
Acta biochimica et biophysica Sinica 2023 May 24;55(5):842-852
Acta biochimica et biophysica Sinica 2023 May 24;55(5):842-852
TMT proteomics analysis reveals the mechanism of bleomycin-induced pulmonary fibrosis and effects of Ginseng honeysuckle superfine powdered tea.
Li X, Yu X, Gao Y, Zhao W, Wang Y, Yu F, Fu C, Gao H, Cheng M, Li B
Chinese medicine 2023 May 24;18(1):60
Chinese medicine 2023 May 24;18(1):60
Ambra1 modulates the sensitivity of mantle cell lymphoma to palbociclib by regulating cyclin D1.
Jiang Z, Zhang A, Wei W, Li S
Scientific reports 2023 May 24;13(1):8389
Scientific reports 2023 May 24;13(1):8389
Hydroxysafflor yellow a confers neuroprotection against acute traumatic brain injury by modulating neuronal autophagy to inhibit NLRP3 inflammasomes.
Lai Z, Li C, Ma H, Hua S, Liu Z, Huang S, Liu K, Li J, Feng Z, Cai Y, Zou Y, Tang Y, Jiang X
Journal of ethnopharmacology 2023 May 23;308:116268
Journal of ethnopharmacology 2023 May 23;308:116268
All-Trans Retinoic Acid-Responsive LGR6 Is Transiently Expressed during Myogenic Differentiation and Is Required for Myoblast Differentiation and Fusion.
Kitakaze T, Tatsumi R, Yamaguchi M, Nakatsuji A, Harada N, Yamaji R
International journal of molecular sciences 2023 May 20;24(10)
International journal of molecular sciences 2023 May 20;24(10)
RBM10 Loss Promotes EGFR-Driven Lung Cancer and Confers Sensitivity to Spliceosome Inhibition.
Bao Y, Zhang S, Zhang X, Pan Y, Yan Y, Wang N, Ren Y, Zuo J, Zong WX, Wang Z, Wang Y
Cancer research 2023 May 2;83(9):1490-1502
Cancer research 2023 May 2;83(9):1490-1502
Reduced hepatic bradykinin degradation accounts for cold-induced BAT thermogenesis and WAT browning in male mice.
Xiao F, Jiang H, Li Z, Jiang X, Chen S, Niu Y, Yin H, Shu Y, Peng B, Lu W, Li X, Li Z, Lan S, Xu X, Guo F
Nature communications 2023 May 2;14(1):2523
Nature communications 2023 May 2;14(1):2523
Epigenetically silenced lncRNA SNAI3-AS1 promotes ferroptosis in glioma via perturbing the m(6)A-dependent recognition of Nrf2 mRNA mediated by SND1.
Zheng J, Zhang Q, Zhao Z, Qiu Y, Zhou Y, Wu Z, Jiang C, Wang X, Jiang X
Journal of experimental & clinical cancer research : CR 2023 May 19;42(1):127
Journal of experimental & clinical cancer research : CR 2023 May 19;42(1):127
Multi-omics analysis of a drug-induced model of bipolar disorder in zebrafish.
Li Y, Zhang L, Mao M, He L, Wang T, Pan Y, Zhao X, Li Z, Mu X, Qian Y, Qiu J
iScience 2023 May 19;26(5):106744
iScience 2023 May 19;26(5):106744
MRPL12-ANT3 interaction involves in acute kidney injury via regulating MPTP of tubular epithelial cells.
Ji X, Chu L, Su D, Sun J, Song P, Sun S, Wang Y, Mu Q, Liu Y, Wan Q
iScience 2023 May 19;26(5):106656
iScience 2023 May 19;26(5):106656
Amphibian pore-forming protein βγ-CAT drives extracellular nutrient scavenging under cell nutrient deficiency.
Liu LZ, Liu L, Shi ZH, Bian XL, Si ZR, Wang QQ, Xiang Y, Zhang Y
iScience 2023 May 19;26(5):106598
iScience 2023 May 19;26(5):106598
C9ORF72 suppresses JAK-STAT mediated inflammation.
Pang W, Hu F
iScience 2023 May 19;26(5):106579
iScience 2023 May 19;26(5):106579
Transcription factor Dmrt1 triggers the SPRY1-NF-κB pathway to maintain testicular immune homeostasis and male fertility.
Zhang MF, Wan SC, Chen WB, Yang DH, Liu WQ, Li BL, Aierken A, Du XM, Li YX, Wu WP, Yang XC, Wei YD, Li N, Peng S, Li XL, Li GP, Hua JL
Zoological research 2023 May 18;44(3):505-521
Zoological research 2023 May 18;44(3):505-521
Evaluation of different rat models intrauterine adhesion models and improvement of the technique for their establishment.
Xi J, Pan Y, Jin C, Liu J, Cheng J, Xu B
Experimental animals 2023 May 17;72(2):274-284
Experimental animals 2023 May 17;72(2):274-284
miR-100-5p Regulates Skeletal Muscle Myogenesis through the Trib2/mTOR/S6K Signaling Pathway.
Wang K, Liufu S, Yu Z, Xu X, Ai N, Li X, Liu X, Chen B, Zhang Y, Ma H, Yin Y
International journal of molecular sciences 2023 May 17;24(10)
International journal of molecular sciences 2023 May 17;24(10)
Adiponectin Attenuates Splenectomy-Induced Cognitive Deficits by Neuroinflammation and Oxidative Stress via TLR4/MyD88/NF-κb Signaling Pathway in Aged Rats.
Zhang Z, Guo L, Yang F, Peng S, Wang D, Lai X, Su B, Xie H
ACS chemical neuroscience 2023 May 17;14(10):1799-1809
ACS chemical neuroscience 2023 May 17;14(10):1799-1809
The High Level of RANKL Improves IκB/p65/Cyclin D1 Expression and Decreases p-Stat5 Expression in Firm Udder of Dairy Goats.
Gao Z, Shao D, Zhao C, Liu H, Zhao X, Wei Q, Ma B
International journal of molecular sciences 2023 May 16;24(10)
International journal of molecular sciences 2023 May 16;24(10)
Recognition Mechanism of a Novel Gabapentinoid Drug, Mirogabalin, for Recombinant Human α(2)δ1, a Voltage-Gated Calcium Channel Subunit.
Kozai D, Numoto N, Nishikawa K, Kamegawa A, Kawasaki S, Hiroaki Y, Irie K, Oshima A, Hanzawa H, Shimada K, Kitano Y, Fujiyoshi Y
Journal of molecular biology 2023 May 15;435(10):168049
Journal of molecular biology 2023 May 15;435(10):168049
CircPVT1 promotes ER-positive breast tumorigenesis and drug resistance by targeting ESR1 and MAVS.
Yi J, Wang L, Hu GS, Zhang YY, Du J, Ding JC, Ji X, Shen HF, Huang HH, Ye F, Liu W
The EMBO journal 2023 May 15;42(10):e112408
The EMBO journal 2023 May 15;42(10):e112408
Interaction of Nmi and IFP35 Promotes Mutual Protein Stabilization and IRF3 and IRF7 Degradation to Suppress Type I IFN Production in Teleost Fish.
Li L, Chen SN, Wang KL, Li N, Pang AN, Liu LH, Li B, Hou J, Wang S, Nie P
Journal of immunology (Baltimore, Md. : 1950) 2023 May 15;210(10):1494-1507
Journal of immunology (Baltimore, Md. : 1950) 2023 May 15;210(10):1494-1507
FOXA2 plays a critical role in hepatocellular carcinoma progression and lenvatinib-associated drug resistance.
Wang Z, Shen J, Chen C, Wen T, Li C
Bioscience trends 2023 May 15;17(2):136-147
Bioscience trends 2023 May 15;17(2):136-147
Elevated nuclear TDP-43 induces constitutive exon skipping.
Carmen-Orozco RP, Tsao W, Ye Y, Sinha IR, Chang K, Trinh V, Chung W, Bowden K, Troncoso JC, Blackshaw S, Hayes LR, Sun S, Wong PC, Ling JP
bioRxiv : the preprint server for biology 2023 May 12;
bioRxiv : the preprint server for biology 2023 May 12;
Structure of Semliki Forest virus in complex with its receptor VLDLR.
Cao D, Ma B, Cao Z, Zhang X, Xiang Y
Cell 2023 May 11;186(10):2208-2218.e15
Cell 2023 May 11;186(10):2208-2218.e15
Lactiplantibacillus plantarum attenuates Coxsackievirus B3-induced pancreatitis through the BAX/BCL2/CASP3 signaling pathway.
Yu X, Zhang Y, Pei K, Tan J, Tian H, Xu T, Liu F, Peng N, Huang Y, Huang X, Huang X, Wu J, Liu Q, Zeng L, Hua W, Huang X
Food & function 2023 May 11;14(9):4129-4142
Food & function 2023 May 11;14(9):4129-4142
Effect of Sublethal Concentrations of Metal Nanomaterials on Cell Energy Metabolism.
Liang C, Jiang Q, Liu Z, Yang J, Zhang J, Zhang S, Xin W
Toxics 2023 May 11;11(5)
Toxics 2023 May 11;11(5)
Interleukin-1 increases cyclooxygenase-2 expression and prostaglandin E2 production in human granulosa-lutein cell via nuclear factor kappa B/P65 and extracellular signal-regulated kinase 1/2 signaling pathways.
Wan S, Chen Q, Xiang Y, Sang Y, Tang M, Song Y, Feng G, Ye B, Bai L, Zhu Y
Molecular and cellular endocrinology 2023 May 1;566-567:111891
Molecular and cellular endocrinology 2023 May 1;566-567:111891
Cancer-associated fibroblasts suppressed ferroptosis in glioblastoma via upregulating lncRNA DLEU1.
Zhao J, Yang S, Lv C, Liu Y
American journal of physiology. Cell physiology 2023 May 1;324(5):C1039-C1052
American journal of physiology. Cell physiology 2023 May 1;324(5):C1039-C1052
EVL and MIM/MTSS1 regulate actin cytoskeletal remodeling to promote dendritic filopodia in neurons.
Parker SS, Ly KT, Grant AD, Sweetland J, Wang AM, Parker JD, Roman MR, Saboda K, Roe DJ, Padi M, Wolgemuth CW, Langlais P, Mouneimne G
The Journal of cell biology 2023 May 1;222(5)
The Journal of cell biology 2023 May 1;222(5)
Soluble TREM-like Transcript-1 Acts as a Damage-Associated Molecular Pattern through the TLR4/MD2 Pathway Contributing to Immune Dysregulation during Sepsis.
Chang CM, Cheng KH, Wei TY, Lu MP, Chen YC, Lu YT
Journal of immunology (Baltimore, Md. : 1950) 2023 May 1;210(9):1351-1362
Journal of immunology (Baltimore, Md. : 1950) 2023 May 1;210(9):1351-1362
Cardiac-specific Trim44 knockout in rat attenuates isoproterenol-induced cardiac remodeling via inhibition of AKT/mTOR pathway.
Jiang XY, Guan FF, Ma JX, Dong W, Qi XL, Zhang X, Chen W, Gao S, Gao X, Pan S, Wang JZ, Ma YW, Zhang LF, Lu D
Disease models & mechanisms 2023 May 1;16(5)
Disease models & mechanisms 2023 May 1;16(5)
FBXO11 amplifies type I interferon signaling to exert antiviral effects by facilitating the assemble of TRAF3-TBK1-IRF3 complex.
Gao L, Gao Y, Han K, Wang Z, Meng F, Liu J, Zhao X, Shao Y, Shen J, Sun W, Liu Y, Xu H, Du X, Li J, Qin FX
Journal of medical virology 2023 Mar;95(3):e28655
Journal of medical virology 2023 Mar;95(3):e28655
SARS-CoV-2 Omicron XBB subvariants exhibit enhanced fusogenicity and substantial immune evasion in elderly population, but high sensitivity to pan-coronavirus fusion inhibitors.
Xia S, Jiao F, Wang L, Yu X, Lu T, Fu Y, Huang Z, Li X, Huang J, Wang Q, Man Q, Xiong L, Jiang S, Lu L
Journal of medical virology 2023 Mar;95(3):e28641
Journal of medical virology 2023 Mar;95(3):e28641
ZNFX1 antisense RNA1 promotes antiviral innate immune responses via modulating ZNFX1 function.
Jia X, Zhang M, Wang H, Cheng C, Li Q, Li Y, Kong L, Lan X, Wang Y, Liang X, Yuan S, Wang Y, Xu A
Journal of medical virology 2023 Mar;95(3):e28637
Journal of medical virology 2023 Mar;95(3):e28637
Ubiquitin E3 ligase β-TrCP negatively regulates surface protein of hepatitis B virus.
Tu W, Liu J, Qian F, Zhu L, Li M, Zheng H, Zhu C
Journal of medical virology 2023 Mar;95(3):e28620
Journal of medical virology 2023 Mar;95(3):e28620
SARS-CoV-2 NSP7 inhibits type I and III IFN production by targeting the RIG-I/MDA5, TRIF, and STING signaling pathways.
Deng J, Zheng Y, Zheng SN, Nan ML, Han L, Zhang J, Jin Y, Pan JA, Gao C, Wang PH
Journal of medical virology 2023 Mar;95(3):e28561
Journal of medical virology 2023 Mar;95(3):e28561
ATG16L1 adopts a dual-binding site mode to interact with WIPI2b in autophagy.
Gong X, Wang Y, Tang Y, Wang Y, Zhang M, Li M, Zhang Y, Pan L
Science advances 2023 Mar;9(9):eadf0824
Science advances 2023 Mar;9(9):eadf0824
YY1 (Yin-Yang 1), a transcription factor regulating systemic inflammation, is involved in cognitive impairment of depression.
Lu J, Jin K, Jiao J, Liu R, Mou T, Chen B, Zhang Z, Jiang C, Zhao H, Wang Z, Zhou R, Huang M
Psychiatry and clinical neurosciences 2023 Mar;77(3):149-159
Psychiatry and clinical neurosciences 2023 Mar;77(3):149-159
A Disintegrin and Metalloproteinase 10 (ADAM10) Is Essential for Oligodendrocyte Precursor Development and Myelination in the Mouse Brain.
Guo D, Huang F, Xue R, Ma Y, Xiao L, Lou H, Pan S
Molecular neurobiology 2023 Mar;60(3):1675-1689
Molecular neurobiology 2023 Mar;60(3):1675-1689
An unconventional cancer-promoting function of methamphetamine in hepatocellular carcinoma.
Si Z, Yang G, Wang X, Yu Z, Pang Q, Zhang S, Qian L, Ruan Y, Huang J, Yu L
Life science alliance 2023 Mar;6(3)
Life science alliance 2023 Mar;6(3)
GBP2 promotes clear cell renal cell carcinoma progression through immune infiltration and regulation of PD‑L1 expression via STAT1 signaling.
Ye S, Li S, Qin L, Zheng W, Liu B, Li X, Ren Z, Zhao H, Hu X, Ye N, Li G
Oncology reports 2023 Mar;49(3)
Oncology reports 2023 Mar;49(3)
Effects of icariin and curcumol on autophagy, ferroptosis, and lipid metabolism based on miR-7/m-TOR/SREBP1 pathway on prostate cancer.
Xu W, Ding J, Li B, Sun T, You X, He Q, Sheng W
BioFactors (Oxford, England) 2023 Mar;49(2):438-456
BioFactors (Oxford, England) 2023 Mar;49(2):438-456
Methionine sulfoxide suppresses adipogenic differentiation by regulating the mitogen-activated protein kinase signaling pathway.
Qin D, Lei Y, Xie W, Zheng Q, Peng Z, Liu Y, Dai B, Ma T, Wei P, Gao C, Guo X, Gao J, Zhao J, Du J, Zeng Q, Zhang Z, Dong X, Shen H
Cell biology international 2023 Mar;47(3):648-659
Cell biology international 2023 Mar;47(3):648-659
RASSF1A inhibits epithelial-mesenchymal transition of gastric cancer cells by downregulating P-JNK.
Bin Y, Deng W, Hu H, Zeng Q, Chen J, Xu Y, Dai Y, Liao A, Xiao W
Cell biology international 2023 Mar;47(3):573-583
Cell biology international 2023 Mar;47(3):573-583
Ginsenoside compound K reduces ischemia/reperfusion-induced neuronal apoptosis by inhibiting PTP1B-mediated IRS1 tyrosine dephosphorylation.
Fu J, Yu L, Yu Q, Yu N, Xu F, Li S
Journal of ginseng research 2023 Mar;47(2):274-282
Journal of ginseng research 2023 Mar;47(2):274-282
p52-ZER6: a determinant of tumor cell sensitivity to MDM2-p53 binding inhibitors.
Li WF, Alfason L, Huang C, Tang Y, Qiu L, Miyagishi M, Wu SR, Kasim V
Acta pharmacologica Sinica 2023 Mar;44(3):647-660
Acta pharmacologica Sinica 2023 Mar;44(3):647-660
The E3 ligase RBCK1 reduces the sensitivity of ccRCC to sunitinib through the ANKRD35-MITD1-ANXA1 axis.
Wang Y, Peng M, Zhong Y, Xiong W, Zhu L, Jin X
Oncogene 2023 Mar;42(13):952-966
Oncogene 2023 Mar;42(13):952-966
hASCs-derived exosomal miR-155-5p targeting TGFβR2 promotes autophagy and reduces pyroptosis to alleviate intervertebral disc degeneration.
Chen D, Jiang X, Zou H
Journal of orthopaedic translation 2023 Mar;39:163-176
Journal of orthopaedic translation 2023 Mar;39:163-176
Cerebrospinal fluid-derived extracellular vesicles after spinal cord injury promote vascular regeneration via PI3K/AKT signaling pathway.
Li C, Qin T, Jin Y, Hu J, Yuan F, Cao Y, Duan C
Journal of orthopaedic translation 2023 Mar;39:124-134
Journal of orthopaedic translation 2023 Mar;39:124-134
Linear ubiquitination of LKB1 activates AMPK pathway to inhibit NLRP3 inflammasome response and reduce chondrocyte pyroptosis in osteoarthritis.
Chen Y, Liu Y, Jiang K, Wen Z, Cao X, Wu S
Journal of orthopaedic translation 2023 Mar;39:1-11
Journal of orthopaedic translation 2023 Mar;39:1-11
miR-124-3p improves mitochondrial function of renal tubular epithelial cells in db/db mice.
Liang L, Wo C, Yuan Y, Cao H, Tan W, Zhou X, Wang D, Chen R, Shi M, Zhang F, Xiao Y, Liu L, Zhou Y, Zhang T, Wang Y, Guo B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22794
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22794
A Physiologically Responsive Nanocomposite Hydrogel for Treatment of Head and Neck Squamous Cell Carcinoma via Proteolysis-Targeting Chimeras Enhanced Immunotherapy.
Wu Y, Chang X, Yang G, Chen L, Wu Q, Gao J, Tian R, Mu W, Gooding JJ, Chen X, Sun S
Advanced materials (Deerfield Beach, Fla.) 2023 Mar;35(12):e2210787
Advanced materials (Deerfield Beach, Fla.) 2023 Mar;35(12):e2210787
HSP90β promotes osteoclastogenesis by dual-activation of cholesterol synthesis and NF-κB signaling.
Cheng HM, Xing M, Zhou YP, Zhang W, Liu Z, Li L, Zheng Z, Ma Y, Li P, Liu X, Li P, Xu X
Cell death and differentiation 2023 Mar;30(3):673-686
Cell death and differentiation 2023 Mar;30(3):673-686
Glioblastoma glycolytic signature predicts unfavorable prognosis, immunological heterogeneity, and ENO1 promotes microglia M2 polarization and cancer cell malignancy.
Liang X, Wang Z, Dai Z, Zhang H, Zhang J, Luo P, Liu Z, Liu Z, Yang K, Cheng Q, Zhang M
Cancer gene therapy 2023 Mar;30(3):481-496
Cancer gene therapy 2023 Mar;30(3):481-496
Transcription factor SOX15 regulates stem cell pluripotency and promotes neural fate during differentiation by activating the neurogenic gene Hes5.
Choi EB, Vodnala M, Saini P, Anugula S, Zerbato M, Ho JJ, Wang J, Ho Sui SJ, Yoon J, Roels M, Inouye C, Fong YW
The Journal of biological chemistry 2023 Mar;299(3):102996
The Journal of biological chemistry 2023 Mar;299(3):102996
USP22 suppresses the NLRP3 inflammasome by degrading NLRP3 via ATG5-dependent autophagy.
Di Q, Zhao X, Tang H, Li X, Xiao Y, Wu H, Wu Z, Quan J, Chen W
Autophagy 2023 Mar;19(3):873-885
Autophagy 2023 Mar;19(3):873-885
SDC1-dependent TGM2 determines radiosensitivity in glioblastoma by coordinating EPG5-mediated fusion of autophagosomes with lysosomes.
Zheng W, Chen Q, Liu H, Zeng L, Zhou Y, Liu X, Bai Y, Zhang J, Pan Y, Shao C
Autophagy 2023 Mar;19(3):839-857
Autophagy 2023 Mar;19(3):839-857
Liraglutide abrogates nephrotoxic effects of chemotherapies.
Xu C, Lu C, Wang Z, Hu X, Li S, Xie Y, Qiu Y, Cao R, Li Y, Yang J
Pharmacological research 2023 Mar;189:106680
Pharmacological research 2023 Mar;189:106680
Chronic spinal cord compression associated with intervertebral disc degeneration in SPARC-null mice.
Li ZY, Zhou AF, Li G, Zhou LY, Pu PM, Zhu K, Zheng Z, Wang YJ, Liang QQ, Yao M, Cui XJ
Neural regeneration research 2023 Mar;18(3):634-642
Neural regeneration research 2023 Mar;18(3):634-642
Ectopic endometriotic stromal cells-derived lactate induces M2 macrophage polarization via Mettl3/Trib1/ERK/STAT3 signalling pathway in endometriosis.
Gou Y, Wang H, Wang T, Wang H, Wang B, Jiao N, Yu Y, Cao Y, Wang H, Zhang Z
Immunology 2023 Mar;168(3):389-402
Immunology 2023 Mar;168(3):389-402
The Effect of Gut Microbiota on the Progression of Intervertebral Disc Degeneration.
Yao B, Cai Y, Wang W, Deng J, Zhao L, Han Z, Wan L
Orthopaedic surgery 2023 Mar;15(3):858-867
Orthopaedic surgery 2023 Mar;15(3):858-867
Hesperidin enhances intestinal barrier function in Caco-2 cell monolayers via AMPK-mediated tight junction-related proteins.
Park HY, Yu JH
FEBS open bio 2023 Mar;13(3):532-544
FEBS open bio 2023 Mar;13(3):532-544
Thioredoxin 1 overexpression attenuated diabetes-induced endoplasmic reticulum stress in Müller cells via apoptosis signal-regulating kinase 1.
Yu X, Teng Q, Bao K, Chudhary M, Qi H, Zhou W, Che H, Liu J, Ren X, Kong L
Journal of cellular biochemistry 2023 Mar;124(3):421-433
Journal of cellular biochemistry 2023 Mar;124(3):421-433
Antidepressant-like effect of CP-101,606: Evidence of mTOR pathway activation.
Qin Y, Guo X, Song W, Liang Z, Wang Y, Feng D, Yang Y, Li M, Gao M
Molecular and cellular neurosciences 2023 Mar;124:103821
Molecular and cellular neurosciences 2023 Mar;124:103821
Metabolism-related lncRNAs signature to predict the prognosis of colon adenocarcinoma.
Sun Y, Liu B, Xiao B, Jiang X, Xiang JJ, Xie J, Hu XM
Cancer medicine 2023 Mar;12(5):5994-6008
Cancer medicine 2023 Mar;12(5):5994-6008
Developmental changes in lipid and fatty acid metabolism and the inhibition by in ovo feeding oleic acid in Muscovy duck embryogenesis.
Zhang X, Wu Q, Zheng W, Liu C, Huang L, Zuo X, Xiao W, Han X, Ye H, Wang W, Yang L, Zhu Y
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2023 Mar;12:321-333
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2023 Mar;12:321-333
Lin28a induced mitochondrial dysfunction in human granulosa cells via suppressing LARS2 expression.
Chen J, Liu W
Cellular signalling 2023 Mar;103:110536
Cellular signalling 2023 Mar;103:110536
Guanylate-binding protein 1 restricts avian coronavirus infectious bronchitis virus-infected HD11 cells.
Ma P, Gu K, Wen R, Li C, Zhou C, Zhao Y, Li H, Lei C, Yang X, Wang H
Poultry science 2023 Mar;102(3):102398
Poultry science 2023 Mar;102(3):102398
Uridine Alleviates Sepsis-Induced Acute Lung Injury by Inhibiting Ferroptosis of Macrophage.
Lai K, Song C, Gao M, Deng Y, Lu Z, Li N, Geng Q
International journal of molecular sciences 2023 Mar 7;24(6)
International journal of molecular sciences 2023 Mar 7;24(6)
p53 directly downregulates the expression of CDC20 to exert anti-tumor activity in mantle cell lymphoma.
Chen Y, Yang P, Wang J, Gao S, Xiao S, Zhang W, Zhu M, Wang Y, Ke X, Jing H
Experimental hematology & oncology 2023 Mar 7;12(1):28
Experimental hematology & oncology 2023 Mar 7;12(1):28
Effects of Caprylic Acid and Eicosapentaenoic Acid on Lipids, Inflammatory Levels, and the JAK2/STAT3 Pathway in ABCA1-Deficient Mice and ABCA1 Knock-Down RAW264.7 Cells.
Zhang X, Zhang P, Liu Y, Liu Z, Xu Q, Zhang Y, Liu L, Yang X, Li L, Xue C
Nutrients 2023 Mar 6;15(5)
Nutrients 2023 Mar 6;15(5)
Isopropyl 3-(3, 4-dihydroxyphenyl)-2-hydroxypropanoate protects lipopolysaccharide-induced acute lung injury in mice by attenuating pyroptosis.
Zhang ML, Wang M, Chen J, Liu YJ, Yu YJ, Liu LM, Zheng XH, Xiao YC, Zhang JM, Zhu MX, Yue X, Zhao Y, Niu W, Li ZC
European journal of pharmacology 2023 Mar 5;942:175545
European journal of pharmacology 2023 Mar 5;942:175545
Sertaconazole nitrate targets IDO1 and regulates the MAPK signaling pathway to induce autophagy and apoptosis in CRC cells.
Yang Y, Jin Y, Yin L, Liu P, Zhu L, Gao H
European journal of pharmacology 2023 Mar 5;942:175515
European journal of pharmacology 2023 Mar 5;942:175515
PKM2/PDK1 dual-targeted shikonin derivatives restore the sensitivity of EGFR-mutated NSCLC cells to gefitinib by remodeling glucose metabolism.
Lin H, Han H, Yang M, Wen Z, Chen Q, Ma Y, Wang X, Wang C, Yin T, Wang X, Lu G, Chen H, Qi J, Yang Y
European journal of medicinal chemistry 2023 Mar 5;249:115166
European journal of medicinal chemistry 2023 Mar 5;249:115166
DNA repair mechanisms that promote insertion-deletion events during immunoglobulin gene diversification.
Hao Q, Zhan C, Lian C, Luo S, Cao W, Wang B, Xie X, Ye X, Gui T, Voena C, Pighi C, Wang Y, Tian Y, Wang X, Dai P, Cai Y, Liu X, Ouyang S, Sun S, Hu Q, Liu J, Ye Y, Zhao J, Lu A, Wang JY, Huang C, Su B, Meng FL, Chiarle R, Pan-Hammarström Q, Yeap LS
Science immunology 2023 Mar 31;8(81):eade1167
Science immunology 2023 Mar 31;8(81):eade1167
The stromal-tumor amplifying STC1-Notch1 feedforward signal promotes the stemness of hepatocellular carcinoma.
Bai S, Zhao Y, Chen W, Peng W, Wang Y, Xiong S, Aruna, Li Y, Yang Y, Chen S, Cheng B, Wang R
Journal of translational medicine 2023 Mar 31;21(1):236
Journal of translational medicine 2023 Mar 31;21(1):236
Ferredoxin 1 regulates granulosa cell apoptosis and autophagy in polycystic ovary syndrome.
Xing J, Qiao G, Luo X, Liu S, Chen S, Ye G, Zhang C, Yi J
Clinical science (London, England : 1979) 2023 Mar 31;137(6):453-468
Clinical science (London, England : 1979) 2023 Mar 31;137(6):453-468
Sustainably released nanoparticle-based rhynchophylline limits pulmonary fibrosis by inhibiting the TEK-PI3K/AKT signaling pathway.
Wang S, Huang Z, Liu Y, Sun H, Zhou Y, Shi J
Translational lung cancer research 2023 Mar 31;12(3):427-445
Translational lung cancer research 2023 Mar 31;12(3):427-445
9-Butyl-Harmol Exerts Antiviral Activity against Newcastle Disease Virus through Targeting GSK-3β and HSP90β.
Wang C, Wang T, Hu R, Duan L, Hou Q, Han Y, Dai J, Wang W, Ren S, Liu H, Wang X, Xiao S, Li N, Wang J, Yang Z
Journal of virology 2023 Mar 30;97(3):e0198422
Journal of virology 2023 Mar 30;97(3):e0198422
All Domains of SARS-CoV-2 nsp1 Determine Translational Shutoff and Cytotoxicity of the Protein.
Frolov I, Agback T, Palchevska O, Dominguez F, Lomzov A, Agback P, Frolova EI
Journal of virology 2023 Mar 30;97(3):e0186522
Journal of virology 2023 Mar 30;97(3):e0186522
Newcastle Disease Virus Manipulates Mitochondrial MTHFD2-Mediated Nucleotide Metabolism for Virus Replication.
Tang N, Chen P, Zhao C, Liu P, Tan L, Song C, Qiu X, Liao Y, Liu X, Luo T, Sun Y, Ding C
Journal of virology 2023 Mar 30;97(3):e0001623
Journal of virology 2023 Mar 30;97(3):e0001623
Theabrownin Isolated from Pu-Erh Tea Enhances the Innate Immune and Anti-Inflammatory Effects of RAW264.7 Macrophages via the TLR2/4-Mediated Signaling Pathway.
Zhao L, Miao Y, Shan B, Zhao C, Peng C, Gong J
Foods (Basel, Switzerland) 2023 Mar 30;12(7)
Foods (Basel, Switzerland) 2023 Mar 30;12(7)
RPL11 promotes non-small cell lung cancer cell proliferation by regulating endoplasmic reticulum stress and cell autophagy.
Chen J, Lei C, Zhang H, Huang X, Yang Y, Liu J, Jia Y, Shi H, Zhang Y, Zhang J, Du J
BMC molecular and cell biology 2023 Mar 3;24(1):7
BMC molecular and cell biology 2023 Mar 3;24(1):7
PVT1/miR-136/Sox2/UPF1 axis regulates the malignant phenotypes of endometrial cancer stem cells.
Li Q, Kong F, Cong R, Ma J, Wang C, Ma X
Cell death & disease 2023 Mar 3;14(3):177
Cell death & disease 2023 Mar 3;14(3):177
Comprehensive proteogenomic characterization of early duodenal cancer reveals the carcinogenesis tracks of different subtypes.
Li L, Jiang D, Liu H, Guo C, Zhao R, Zhang Q, Xu C, Qin Z, Feng J, Liu Y, Wang H, Chen W, Zhang X, Li B, Bai L, Tian S, Tan S, Yu Z, Chen L, Huang J, Zhao JY, Hou Y, Ding C
Nature communications 2023 Mar 29;14(1):1751
Nature communications 2023 Mar 29;14(1):1751
A new ferrocene derivative blocks KRAS localization and function by oxidative modification at His95.
Rehl KM, Selvakumar J, Hoang D, Arumugam K, Gorfe AA, Cho KJ
bioRxiv : the preprint server for biology 2023 Mar 29;
bioRxiv : the preprint server for biology 2023 Mar 29;
Baicalin facilitates remyelination and suppresses neuroinflammation in rats with chronic cerebral hypoperfusion by activating Wnt/β-catenin and inhibiting NF-κB signaling.
Xiao Y, Guan T, Yang X, Xu J, Zhang J, Qi Q, Teng Z, Dong Y, Gao Y, Li M, Meng N, Lv P
Behavioural brain research 2023 Mar 28;442:114301
Behavioural brain research 2023 Mar 28;442:114301
Role of Berberine Thermosensitive Hydrogel in Periodontitis via PI3K/AKT Pathway In Vitro.
Wang C, Liu C, Liang C, Qu X, Zou X, Du S, Zhang Q, Wang L
International journal of molecular sciences 2023 Mar 28;24(7)
International journal of molecular sciences 2023 Mar 28;24(7)
PARM1 Drives Smooth Muscle Cell Proliferation in Pulmonary Arterial Hypertension via AKT/FOXO3A Axis.
He Z, Chang T, Chen Y, Wang H, Dai L, Zeng H
International journal of molecular sciences 2023 Mar 28;24(7)
International journal of molecular sciences 2023 Mar 28;24(7)
Identification of biomarkers of hepatocellular carcinoma gene prognosis based on the immune-related lncRNA signature of transcriptome data.
Ma A, Sun Y, Ogbodu RO, Xiao L, Deng H, Zhou H
Functional & integrative genomics 2023 Mar 28;23(2):104
Functional & integrative genomics 2023 Mar 28;23(2):104
Hyperglycemia induces PFKFB3 overexpression and promotes malignant phenotype of breast cancer through RAS/MAPK activation.
Cheng X, Jia X, Wang C, Zhou S, Chen J, Chen L, Chen J
World journal of surgical oncology 2023 Mar 28;21(1):112
World journal of surgical oncology 2023 Mar 28;21(1):112
CD137 signaling aggravates myocardial ischemia-reperfusion injury by inhibiting mitophagy mediated NLRP3 inflammasome activation.
Zang GY, Yin Q, Shao C, Sun Z, Zhang LL, Xu Y, Li LH, Wang ZQ
Journal of geriatric cardiology : JGC 2023 Mar 28;20(3):223-237
Journal of geriatric cardiology : JGC 2023 Mar 28;20(3):223-237
Downregulated annexin A1 expression correlates with poor prognosis, metastasis, and immunosuppressive microenvironment in Ewing's sarcoma.
Shi X, Wu Y, Tang L, Ni H, Xu Y
Aging 2023 Mar 28;15(6):2321-2346
Aging 2023 Mar 28;15(6):2321-2346
The Construction and Immunogenicity Analyses of a Recombinant Pseudorabies Virus with Senecavirus A VP2 Protein Coexpression.
Tao Q, Zhu L, Xu L, Yang Y, Zhang Y, Liu Z, Xu T, Wen J, Deng L, Zhou Y, Xu Z
Microbiology spectrum 2023 Mar 28;11(2):e0522922
Microbiology spectrum 2023 Mar 28;11(2):e0522922
Microglial aryl hydrocarbon receptor enhances phagocytic function via SYK and promotes remyelination in the cuprizone mouse model of demyelination.
Wang Y, Sun J, Zhu K, Wang D, Zhao X, Zhang H, Wu S, Wang Y, Wang J
Journal of neuroinflammation 2023 Mar 25;20(1):83
Journal of neuroinflammation 2023 Mar 25;20(1):83
FZD7, Regulated by Non-CpG Methylation, Plays an Important Role in Immature Porcine Sertoli Cell Proliferation.
Yang A, Yan S, Yin Y, Chen C, Tang X, Ran M, Chen B
International journal of molecular sciences 2023 Mar 24;24(7)
International journal of molecular sciences 2023 Mar 24;24(7)
The rhythmic coupling of Egr-1 and Cidea regulates age-related metabolic dysfunction in the liver of male mice.
Wu J, Bu D, Wang H, Shen D, Chong D, Zhang T, Tao W, Zhao M, Zhao Y, Fang L, Li P, Xue B, Li CJ
Nature communications 2023 Mar 24;14(1):1634
Nature communications 2023 Mar 24;14(1):1634
Podocyte-specific deletion of ubiquitin carboxyl-terminal hydrolase L1 causes podocyte injury by inducing endoplasmic reticulum stress.
Hu Y, Qi C, Shi J, Tan W, Adiljan Abdurusul, Zhao Z, Xu Y, Wu H, Zhang Z
Cellular and molecular life sciences : CMLS 2023 Mar 23;80(4):106
Cellular and molecular life sciences : CMLS 2023 Mar 23;80(4):106
The OTUD1-Notch2-ICD axis orchestrates allogeneic T cell-mediated graft-versus-host disease.
Cheng Q, Wang D, Lai X, Liu Y, Zuo Y, Zhang W, Lei L, Chen J, Liu H, Wang Y, Liu H, Zheng H, Wu D, Xu Y
Blood 2023 Mar 23;141(12):1474-1488
Blood 2023 Mar 23;141(12):1474-1488
p38-mediated FOXN3 phosphorylation modulates lung inflammation and injury through the NF-κB signaling pathway.
Zhu X, Huang B, Zhao F, Lian J, He L, Zhang Y, Ji L, Zhang J, Yan X, Zeng T, Ma C, Liang Y, Zhang C, Lin J
Nucleic acids research 2023 Mar 21;51(5):2195-2214
Nucleic acids research 2023 Mar 21;51(5):2195-2214
Activating mitofusins interrupts mitochondrial degeneration and delays disease progression in SOD1 mutant amyotrophic lateral sclerosis.
Dang X, Zhang L, Franco A, Dorn Ii GW
Human molecular genetics 2023 Mar 20;32(7):1208-1222
Human molecular genetics 2023 Mar 20;32(7):1208-1222
Prediction and Verification of Curcumin as a Potential Drug for Inhibition of PDCoV Replication in LLC-PK1 Cells.
Wang X, Wang X, Zhang J, Shan Q, Zhu Y, Xu C, Wang J
International journal of molecular sciences 2023 Mar 20;24(6)
International journal of molecular sciences 2023 Mar 20;24(6)
TUBA1C: a new potential target of LncRNA EGFR-AS1 promotes gastric cancer progression.
Wang H, Cui H, Yang X, Peng L
BMC cancer 2023 Mar 20;23(1):258
BMC cancer 2023 Mar 20;23(1):258
Dietary choline metabolite TMAO impairs cognitive function and induces hippocampal synaptic plasticity declining through the mTOR/P70S6K/4EBP1 pathway.
Zhou S, Liu J, Sun Y, Xu P, Liu JL, Sun S, Zhu B, Wu H
Food & function 2023 Mar 20;14(6):2881-2895
Food & function 2023 Mar 20;14(6):2881-2895
Aberrant Activation of the STING-TBK1 Pathway in γδ T Cells Regulates Immune Responses in Oral Lichen Planus.
Huang S, Tan YQ, Zhou G
Biomedicines 2023 Mar 20;11(3)
Biomedicines 2023 Mar 20;11(3)
Secreted protease PRSS35 suppresses hepatocellular carcinoma by disabling CXCL2-mediated neutrophil extracellular traps.
Wang T, Zhou Y, Zhou Z, Zhang P, Yan R, Sun L, Ma W, Zhang T, Shen S, Liu H, Lu H, Ye L, Feng J, Chen Z, Zhong X, Wu G, Cai Y, Jia W, Gao P, Zhang H
Nature communications 2023 Mar 18;14(1):1513
Nature communications 2023 Mar 18;14(1):1513
An XBP1s-PIM-2 positive feedback loop controls IL-15-mediated survival of natural killer cells.
Ma S, Han J, Li Z, Xiao S, Zhang J, Yan J, Tang T, Barr T, Kraft AS, Caligiuri MA, Yu J
Science immunology 2023 Mar 17;8(81):eabn7993
Science immunology 2023 Mar 17;8(81):eabn7993
PPT1 regulation of HSP90α depalmitoylation participates in the pathogenesis of hyperandrogenism.
Xue T, Zhao S, Zhang H, Tang T, Zheng L, Jing J, Ge X, Ma R, Ma J, Ren X, Jueraitetibaike K, Guo Z, Chen L, Yao B
iScience 2023 Mar 17;26(3):106131
iScience 2023 Mar 17;26(3):106131
Hsp22 pretreatment protects against LPS-induced hippocampal injury by alleviating neuroinflammation and apoptosis by regulating the NLRP3/Caspase1/IL-1β signaling pathway in mice.
Peng S, Yu Y, Li J, Jiang D, Xu G, Wu L, Hu J
Aging 2023 Mar 17;15(6):1977-2004
Aging 2023 Mar 17;15(6):1977-2004
SIM imaging resolves endocytosis of SARS-CoV-2 spike RBD in living cells.
Miao L, Yan C, Chen Y, Zhou W, Zhou X, Qiao Q, Xu Z
Cell chemical biology 2023 Mar 16;30(3):248-260.e4
Cell chemical biology 2023 Mar 16;30(3):248-260.e4
Efficient tumor synergistic chemoimmunotherapy by self-augmented ROS-responsive immunomodulatory polymeric nanodrug.
Song J, Cheng M, Xie Y, Li K, Zang X
Journal of nanobiotechnology 2023 Mar 16;21(1):93
Journal of nanobiotechnology 2023 Mar 16;21(1):93
DnaJC7 specifically regulates tau seeding.
Perez VA, Sanders DW, Mendoza-Oliva A, Stopschinski BE, Mullapudi V, White CL 3rd, Joachimiak LA, Diamond MI
bioRxiv : the preprint server for biology 2023 Mar 16;
bioRxiv : the preprint server for biology 2023 Mar 16;
Proteome profiling of the prefrontal cortex of Fmr1 knockout mouse reveals enhancement of complement and coagulation cascades.
Gao MM, Shi H, Yan HJ, Long YS
Journal of proteomics 2023 Mar 15;274:104822
Journal of proteomics 2023 Mar 15;274:104822
RIG-I Promotes Tumorigenesis and Confers Radioresistance of Esophageal Squamous Cell Carcinoma by Regulating DUSP6.
Li L, Lv L, Xu JC, He Q, Chang N, Cui YY, Tao ZC, Zhu T, Qian LT
International journal of molecular sciences 2023 Mar 15;24(6)
International journal of molecular sciences 2023 Mar 15;24(6)
Combination therapy with ultrasound and 2D nanomaterials promotes recovery after spinal cord injury via Piezo1 downregulation.
Zhang F, He X, Dong K, Yang L, Ma B, Liu Y, Liu Z, Chen B, Zhu R, Cheng L
Journal of nanobiotechnology 2023 Mar 15;21(1):91
Journal of nanobiotechnology 2023 Mar 15;21(1):91
CENP-I directly targets centromeric DNA to support CENP-A deposition and centromere maintenance.
Hu L, Zhao C, Liu M, Liu S, Ye J, Wang K, Shi J, Tian W, He X
Proceedings of the National Academy of Sciences of the United States of America 2023 Mar 14;120(11):e2219170120
Proceedings of the National Academy of Sciences of the United States of America 2023 Mar 14;120(11):e2219170120
IFIT2 Depletion Promotes Cancer Stem Cell-like Phenotypes in Oral Cancer.
Lai KC, Regmi P, Liu CJ, Lo JF, Lee TC
Biomedicines 2023 Mar 14;11(3)
Biomedicines 2023 Mar 14;11(3)
Vascular Endothelial Growth Factor A Contributes to Increased Mammalian Respiratory Epithelial Permeability Induced by Pasteurella multocida Infection.
Lin L, Yang J, Zhang D, Lv Q, Wang F, Liu P, Wang M, Shi C, Huang X, Liang W, Tan C, Wang X, Chen H, Wilson BA, Wu B, Peng Z
Microbiology spectrum 2023 Mar 14;11(2):e0455422
Microbiology spectrum 2023 Mar 14;11(2):e0455422
A novel cuproptosis-related gene signature to predict prognosis in Glioma.
Zhang M, Liu X, Wang D, Ruan X, Wang P, Liu L, Xue Y
BMC cancer 2023 Mar 13;23(1):237
BMC cancer 2023 Mar 13;23(1):237
Adipocyte YTH N(6)-methyladenosine RNA-binding protein 1 protects against obesity by promoting white adipose tissue beiging in male mice.
Yan S, Zhou X, Wu C, Gao Y, Qian Y, Hou J, Xie R, Han B, Chen Z, Wei S, Gao X
Nature communications 2023 Mar 13;14(1):1379
Nature communications 2023 Mar 13;14(1):1379
CCP1, a Regulator of Tubulin Post-Translational Modifications, Potentially Plays an Essential Role in Cerebellar Development.
Pang B, Araki A, Zhou L, Takebayashi H, Harada T, Kadota K
International journal of molecular sciences 2023 Mar 10;24(6)
International journal of molecular sciences 2023 Mar 10;24(6)
Canagliflozin ameliorates the development of NAFLD by preventing NLRP3-mediated pyroptosis through FGF21-ERK1/2 pathway.
Huang S, Wu B, He Y, Qiu R, Yang T, Wang S, Lei Y, Li H, Zheng F
Hepatology communications 2023 Mar 1;7(3):e0045
Hepatology communications 2023 Mar 1;7(3):e0045
The Qi-Bang-Yi-Shen formula ameliorates renal dysfunction and fibrosis in rats with diabetic kidney disease via regulating PI3K/AKT, ERK and PPARγ signaling pathways.
Wang Z, Jian G, Chen T, Chen Y, Li J, Wang N
European journal of histochemistry : EJH 2023 Mar 1;67(1)
European journal of histochemistry : EJH 2023 Mar 1;67(1)
Pinellia ternata lectin induces inflammation through TLR4 receptor and mediates PI3K/Akt/mTOR axis to regulate NF-κB signaling pathway.
Li J, Wang W, Yuan Y, Cui X, Bian H, Wen H, Zhang X, Yu H, Wu H
Toxicology 2023 Mar 1;486:153430
Toxicology 2023 Mar 1;486:153430
Effects and mechanisms of Xiaochaihu Tang against liver fibrosis: An integration of network pharmacology, molecular docking and experimental validation.
Wang SJ, Ye W, Li WY, Tian W, Zhang M, Sun Y, Feng YD, Liu CX, Liu SY, Cao W, Meng JR, Li XQ
Journal of ethnopharmacology 2023 Mar 1;303:116053
Journal of ethnopharmacology 2023 Mar 1;303:116053
Exploring the potential of ginseng glycoprotein to improve learning and memory in mice via Notch signaling pathway and structural analysis using multi-information fusion based on liquid chromatography-mass spectrometry.
Fang X, Zhang X, Zhang Y, Zhang X, Shan M, Guan S, Qiu Z, Zhu D, Luo H
Journal of ethnopharmacology 2023 Mar 1;303:115978
Journal of ethnopharmacology 2023 Mar 1;303:115978
Identification of menaquinone-4 (vitamin K2) target genes in bovine endometrial epithelial cells in vitro.
Bai H, Kawahara M, Takahashi M
Theriogenology 2023 Mar 1;198:183-193
Theriogenology 2023 Mar 1;198:183-193
Gold nanoparticles inhibit tumor growth via targeting the Warburg effect in a c-Myc-dependent way.
Sun L, Liu Y, Yang N, Ye X, Liu Z, Wu J, Zhou M, Zhong W, Cao M, Zhang J, Mequanint K, Xing M, Liao W
Acta biomaterialia 2023 Mar 1;158:583-598
Acta biomaterialia 2023 Mar 1;158:583-598
TP63 gain-of-function mutations cause premature ovarian insufficiency by inducing oocyte apoptosis.
Huang C, Zhao S, Yang Y, Guo T, Ke H, Mi X, Qin Y, Chen ZJ, Zhao S
The Journal of clinical investigation 2023 Mar 1;133(5)
The Journal of clinical investigation 2023 Mar 1;133(5)
CRISPR/Cas9 screen uncovers functional translation of cryptic lncRNA-encoded open reading frames in human cancer.
Zheng C, Wei Y, Zhang P, Xu L, Zhang Z, Lin K, Hou J, Lv X, Ding Y, Chiu Y, Jain A, Islam N, Malovannaya A, Wu Y, Ding F, Xu H, Sun M, Chen X, Chen Y
The Journal of clinical investigation 2023 Mar 1;133(5)
The Journal of clinical investigation 2023 Mar 1;133(5)
SARS-CoV-2 NSP13 interacts with host IRF3, blocking antiviral immune responses.
Feng K, Zhang HJ, Min YQ, Zhou M, Deng F, Wang HL, Li PQ, Ning YJ
Journal of medical virology 2023 Jun;95(6):e28881
Journal of medical virology 2023 Jun;95(6):e28881
TMEM2 induces epithelial-mesenchymal transition and promotes resistance to temozolomide in GBM cells.
Gao L, Tong S, Liu J, Cai J, Ye Z, Zhou L, Song P, Li Z, Lei P, Wei H, Hua Q, Tian D, Cai Q
Heliyon 2023 Jun;9(6):e16559
Heliyon 2023 Jun;9(6):e16559
Glutaredoxin 1 protects lens epithelial cells from epithelial-mesenchymal transition by preventing casein kinase 1α S-glutathionylation during posterior capsular opacification.
Li C, Chen X, Zhang S, Liang C, Ma X, Zhang R, Yan H
Redox biology 2023 Jun;62:102676
Redox biology 2023 Jun;62:102676
Exercise improves homeostasis of the intestinal epithelium by activation of apelin receptor-AMP-activated protein kinase signalling.
Chae SA, Du M, Son JS, Zhu MJ
The Journal of physiology 2023 Jun;601(12):2371-2389
The Journal of physiology 2023 Jun;601(12):2371-2389
Dysfunction of NRG1/ErbB4 Signaling in the Hippocampus Might Mediate Long-term Memory Decline After Systemic Inflammation.
Gao YZ, Wu XM, Zhou ZQ, Liu PM, Yang JJ, Ji MH
Molecular neurobiology 2023 Jun;60(6):3210-3226
Molecular neurobiology 2023 Jun;60(6):3210-3226
The YTHDC1/GLUT3/RNF183 axis forms a positive feedback loop that modulates glucose metabolism and bladder cancer progression.
Yan B, Li X, Peng M, Zuo Y, Wang Y, Liu P, Ren W, Jin X
Experimental & molecular medicine 2023 Jun;55(6):1145-1158
Experimental & molecular medicine 2023 Jun;55(6):1145-1158
ARID3A plays a key regulatory role in palmitic acid-stimulated milk fat synthesis in mouse mammary epithelial cells.
Guo X, Qi H, Lin G, Yu J, Zhang M, Gao X
Cell biology international 2023 Jun;47(6):1106-1117
Cell biology international 2023 Jun;47(6):1106-1117
TLR2-mediated NF-κB signaling pathway is involved in PPV1-induced apoptosis in PK-15 cells.
Xu M, Jin X, Zhang C, Liao H, Wang P, Zhou Y, Song Y, Xia L, Wang L
Veterinary research communications 2023 Jun;47(2):397-407
Veterinary research communications 2023 Jun;47(2):397-407
Chlorogenic Acid Alleviates Hepatic Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress, Inflammation, and Mitochondria-Mediated Apoptosis In Vivo and In Vitro.
Li K, Feng Z, Wang L, Ma X, Wang L, Liu K, Geng X, Peng C
Inflammation 2023 Jun;46(3):1061-1076
Inflammation 2023 Jun;46(3):1061-1076
Thioredoxin-1 regulates IRE1α to ameliorate sepsis-induced NLRP3 inflammasome activation and oxidative stress in Raw 264.7 cell.
Shao R, Lou X, Xue J, Yang Y, Ning D, Chen G, Jiang L
Immunopharmacology and immunotoxicology 2023 Jun;45(3):277-286
Immunopharmacology and immunotoxicology 2023 Jun;45(3):277-286
Tabersonine, a natural NLRP3 inhibitor, suppresses inflammasome activation in macrophages and attenuate NLRP3-driven diseases in mice.
Xu HW, Li WF, Hong SS, Shao JJ, Chen JH, Chattipakorn N, Wu D, Luo W, Liang G
Acta pharmacologica Sinica 2023 Jun;44(6):1252-1261
Acta pharmacologica Sinica 2023 Jun;44(6):1252-1261
Quantitative proteomics of sperm tail in asthenozoospermic patients: exploring the molecular pathways affecting sperm motility.
Mirshahvaladi S, Topraggaleh TR, Bucak MN, Rahimizadeh P, Shahverdi A
Cell and tissue research 2023 Jun;392(3):793-810
Cell and tissue research 2023 Jun;392(3):793-810
Hawthorn fruit extract protect against MC-LR-induced hepatotoxicity by attenuating oxidative stress and apoptosis.
Wang Y, Guo Y, Liu H, Du X, Shi L, Wang W, Zhang S
Environmental toxicology 2023 Jun;38(6):1239-1250
Environmental toxicology 2023 Jun;38(6):1239-1250
A novel nano material for anti-cerebral ischaemia: preparation and application of borneol angelica polysaccharide liposomes.
Ding H, Wang K, He LQ, Yang XY, Huang HH, Liu WL, Xiao C, Du ZX, Yu L, Zhang W
Journal of liposome research 2023 Jun;33(2):144-153
Journal of liposome research 2023 Jun;33(2):144-153
Loss of exosomal miR-200b-3p from hypoxia cancer-associated fibroblasts promotes tumorigenesis and reduces sensitivity to 5-Flourouracil in colorectal cancer via upregulation of ZEB1 and E2F3.
Gong W, Guo Y, Yuan H, Chai R, Wan Z, Zheng B, Hu X, Chen B, Gao S, Dai Q, Yu P, Tu S
Cancer gene therapy 2023 Jun;30(6):905-916
Cancer gene therapy 2023 Jun;30(6):905-916
A Genome-Wide Association Study for Susceptibility to Axial Length in Highly Myopic Eyes.
Lu Q, Du Y, Zhang Y, Chen Y, Li H, He W, Tang Y, Zhao Z, Zhang Y, Wu J, Zhu X, Lu Y
Phenomics (Cham, Switzerland) 2023 Jun;3(3):255-267
Phenomics (Cham, Switzerland) 2023 Jun;3(3):255-267
Oculocerebrorenal syndrome of Lowe (OCRL) controls leukemic T-cell survival by preventing excessive PI(4,5)P(2) hydrolysis in the plasma membrane.
Chen H, Lu C, Tan Y, Weber-Boyvat M, Zheng J, Xu M, Xiao J, Liu S, Tang Z, Lai C, Li M, Olkkonen VM, Yan D, Zhong W
The Journal of biological chemistry 2023 Jun;299(6):104812
The Journal of biological chemistry 2023 Jun;299(6):104812
Disruption of the ADAM17/NF-κB feedback loop in astrocytes ameliorates HIV-1 Tat-induced inflammatory response and neuronal death.
Qiu X, Wang J, Zhang W, Duan C, Chen T, Zhang D, Su J, Gao L
Journal of neurovirology 2023 Jun;29(3):283-296
Journal of neurovirology 2023 Jun;29(3):283-296
Baicalin and baicalein attenuate hyperuricemic nephropathy via inhibiting PI3K/AKT/NF-κB signalling pathway.
Liu Z, Xiang H, Deng Q, Fu W, Li Y, Yu Z, Qiu Y, Mei Z, Xu L
Nephrology (Carlton, Vic.) 2023 Jun;28(6):315-327
Nephrology (Carlton, Vic.) 2023 Jun;28(6):315-327
Donor graft METTL3 gene transfer ameliorates rat liver transplantation ischemia-reperfusion injury by enhancing HO-1 expression in an m(6)A-dependent manner.
Xiang S, Wang Y, Lei D, Luo Y, Peng D, Zong K, Liu Y, Huang Z, Mo S, Pu X, Zheng J, Wu Z
Clinical immunology (Orlando, Fla.) 2023 Jun;251:109325
Clinical immunology (Orlando, Fla.) 2023 Jun;251:109325
BACH1 promotes intervertebral disc degeneration by regulating HMOX1/GPX4 to mediate oxidative stress, ferroptosis, and lipid metabolism in nucleus pulposus cells.
Yao B, Cai Y, Wan L, Deng J, Zhao L, Wang W, Han Z
The journal of gene medicine 2023 Jun;25(6):e3488
The journal of gene medicine 2023 Jun;25(6):e3488
Silencing of FAM111B inhibits tumor growth and promotes apoptosis by decreasing AKT activity in ovarian cancer.
Wang W, Gu Y, Ni H, Quan Q, Guo L
Experimental biology and medicine (Maywood, N.J.) 2023 Jun;248(12):1043-1055
Experimental biology and medicine (Maywood, N.J.) 2023 Jun;248(12):1043-1055
Upregulation of CSNK1A1 induced by ITGB5 confers to hepatocellular carcinoma resistance to sorafenib in vivo by disrupting the EPS15/EGFR complex.
Gu L, Jin X, Liang H, Yang C, Zhang Y
Pharmacological research 2023 Jun;192:106789
Pharmacological research 2023 Jun;192:106789
Charged multivesicular body protein 2B ameliorates biliary injury in the liver from donation after cardiac death rats via autophagy with air-oxygenated normothermic machine perfusion.
Bai Y, Shi JH, Liu Q, Yang DJ, Yan ZP, Zhang JK, Tang HW, Guo WZ, Jin Y, Zhang SJ
Biochimica et biophysica acta. Molecular basis of disease 2023 Jun;1869(5):166686
Biochimica et biophysica acta. Molecular basis of disease 2023 Jun;1869(5):166686
Discovery of alantolactone as a naturally occurring NLRP3 inhibitor to alleviate NLRP3-driven inflammatory diseases in mice.
Li W, Xu H, Shao J, Chen J, Lin Y, Zheng Z, Wang Y, Luo W, Liang G
British journal of pharmacology 2023 Jun;180(12):1634-1647
British journal of pharmacology 2023 Jun;180(12):1634-1647
Ginsenoside Rb1 improves energy metabolism after spinal cord injury.
Wen S, Zou ZR, Cheng S, Guo H, Hu HS, Zeng FZ, Mei XF
Neural regeneration research 2023 Jun;18(6):1332-1338
Neural regeneration research 2023 Jun;18(6):1332-1338
An integrated strategy combining network toxicology and feature-based molecular networking for exploring hepatotoxic constituents and mechanism of Epimedii Folium-induced hepatotoxicity in vitro.
Zhao Z, Du JF, Wang QL, Qiu FN, Chen XY, Liu FJ, Li P, Jiang Y, Li HJ
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jun;176:113785
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jun;176:113785
MiR-5622-3p inhibits ZCWPW1 to induce apoptosis in silica-exposed mice and spermatocyte cells.
Zhao M, Zhou G, Wang J, Zhang Y, Xue J, Liu J, Xie J, Ren L, Zhou X
Nanotoxicology 2023 Jun;17(4):372-384
Nanotoxicology 2023 Jun;17(4):372-384
Baicalin ameliorates multidrug-resistant Pseudomonas aeruginosa induced pulmonary inflammation in rat via arginine biosynthesis.
Li L, Cui H, Zhang Y, Xie W, Lin Y, Guo Y, Huang T, Xue B, Guo W, Huang Z, Man T, Yu H, Zhai Z, Cheng M, Wang M, Lei H, Wang C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114660
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114660
NPTX2 Promotes Epithelial-Mesenchymal Transition in Cutaneous Squamous Cell Carcinoma through METTL3-Mediated N6-Methyladenosine Methylation of SNAIL.
Kang T, Zhang C, Lei H, Luo R, Liu M, Wang S, Zhang X, Duan Q, Xiao S, Zheng Y
The Journal of investigative dermatology 2023 Jun;143(6):977-988.e2
The Journal of investigative dermatology 2023 Jun;143(6):977-988.e2
Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer.
Wang X, Xu J, Sun Y, Cao S, Zeng H, Jin N, Shou M, Tang S, Chen Y, Huang M
Acta pharmaceutica Sinica. B 2023 Jun;13(6):2601-2612
Acta pharmaceutica Sinica. B 2023 Jun;13(6):2601-2612
Anti-oxidative-initiated cognitive impairment amelioration in Alzheimer's disease model rats through preventive transcutaneous electrical acupoint stimulation.
Weng H, Wang Q, Ye R, Bai Y, Yang H, Xu G, Wang Q
Integrative medicine research 2023 Jun;12(2):100946
Integrative medicine research 2023 Jun;12(2):100946
Piperine ameliorates psoriatic skin inflammation by inhibiting the phosphorylation of STAT3.
Lu H, Gong H, Du J, Gao W, Xu J, Cai X, Yang Y, Xiao H
International immunopharmacology 2023 Jun;119:110221
International immunopharmacology 2023 Jun;119:110221
Inflachromene inhibits intimal hyperplasia through the HMGB1/2- regulated TLR4-NF-κB pathway.
Teng S, Zhu Z, Wu C, He Y, Zhou S
International immunopharmacology 2023 Jun;119:110198
International immunopharmacology 2023 Jun;119:110198
Escherichia coli enhances Th17/Treg imbalance via TLR4/NF-κB signaling pathway in oral lichen planus.
Wang J, Yang J, Xia W, Zhang M, Tang H, Wang K, Zhou C, Qian L, Fan Y
International immunopharmacology 2023 Jun;119:110175
International immunopharmacology 2023 Jun;119:110175
Characterizing the specific mechanism of series processed Coptidis Rhizoma by multi-organ metabolomics combined with network pharmacology and molecular docking.
Zhou N, Wang Y, Zhang Z, Feng W, Liu T, Cao Y, Zhang J, Zhang B, Zheng X, Li K
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154804
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154804
Effect of STK3 on proliferation and apoptosis of pancreatic cancer cells via PI3K/AKT/mTOR pathway.
Chen J, Liu F, Wu J, Yang Y, He J, Wu F, Yang K, Li J, Jiang Z, Jiang Z
Cellular signalling 2023 Jun;106:110642
Cellular signalling 2023 Jun;106:110642
Elevated expression of myosin VI contributes to breast cancer progression via MAPK/ERK signaling pathway.
Zhan XJ, Wang R, Kuang XR, Zhou JY, Hu XL
Cellular signalling 2023 Jun;106:110633
Cellular signalling 2023 Jun;106:110633
Wnt3a-Loaded Extracellular Vesicles Promote Alveolar Epithelial Regeneration after Lung Injury.
Gao L, Sun Y, Zhang X, Ma D, Xie A, Wang E, Cheng L, Liu S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(18):e2206606
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(18):e2206606
Discovery of a New-Generation S-Adenosylmethionine-Noncompetitive Covalent Inhibitor Targeting the Lysine Methyltransferase Enhancer of Zeste Homologue 2.
Zhang Y, Yang H, Li B, Li J, Li H, Shi Q, Li B, Wang Z, Zheng J, Zhang Y, Dong H, Huang X, Wang Y
Journal of medicinal chemistry 2023 Jun 8;66(11):7629-7644
Journal of medicinal chemistry 2023 Jun 8;66(11):7629-7644
Silencing mouse circular RNA circSlc8a1 by circular antisense cA-circSlc8a1 induces cardiac hepatopathy.
Wu N, Li F, Yang W, Du WW, Awan FM, Zhang C, Lyu J, Misir S, Zeng K, Eshaghi E, Yang BB
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Jun 7;31(6):1688-1704
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Jun 7;31(6):1688-1704
A copper complex that combats triple negative breast cancer by restraining angiogenesis.
Zheng H, Hu C, Quan Y, Ye X, Shi X, Guo Z, Wang X
Dalton transactions (Cambridge, England : 2003) 2023 Jun 6;52(22):7626-7634
Dalton transactions (Cambridge, England : 2003) 2023 Jun 6;52(22):7626-7634
Taurochenodeoxycholic acid inhibits intestinal epithelial cell proliferation and induces apoptosis independent of the farnesoid X receptor.
Liu Y, Niu K, Wang R, Liang X, Lin C, Wu X, Zhai Z
Food & function 2023 Jun 6;14(11):5277-5289
Food & function 2023 Jun 6;14(11):5277-5289
Discovery of bipyridine amide derivatives targeting pRXRα-PLK1 interaction for anticancer therapy.
Chen J, Zhao T, He F, Zhong Y, Wang S, Tang Z, Qiu Y, Wu Z, Fang M
European journal of medicinal chemistry 2023 Jun 5;254:115341
European journal of medicinal chemistry 2023 Jun 5;254:115341
Preparation of nanocomposite membranes loaded with taxifolin liposome and its mechanism of wound healing in diabetic mice.
Ding Q, Ding C, Liu X, Zheng Y, Zhao Y, Zhang S, Sun S, Peng Z, Liu W
International journal of biological macromolecules 2023 Jun 30;241:124537
International journal of biological macromolecules 2023 Jun 30;241:124537
Role of ionizing radiation activated NRF2 in lung cancer radioresistance.
Xu Q, Zhang P, Han X, Ren H, Yu W, Hao W, Luo B, Khan MI, Chen N
International journal of biological macromolecules 2023 Jun 30;241:124476
International journal of biological macromolecules 2023 Jun 30;241:124476
MAGOH is correlated with poor prognosis and is essential for cell proliferation in lower-grade glioma.
Xiao F, Long Z, Guo Y, Zhu H, Zhang Z, Xiao Y, Hu G, Yang Q, Huang K, Guo H
Aging 2023 Jun 30;15(12):5713-5733
Aging 2023 Jun 30;15(12):5713-5733
AAV9-Tspyl2 gene therapy retards bleomycin-induced pulmonary fibrosis by modulating downstream TGF-β signaling in mice.
Zhang S, Tong X, Liu S, Huang J, Zhang L, Zhang T, Wang D, Fan H
Cell death & disease 2023 Jun 30;14(6):389
Cell death & disease 2023 Jun 30;14(6):389
DnaJC7 specifically regulates tau seeding.
Perez VA, Sanders DW, Mendoza-Oliva A, Stopschinski BE, Mullapudi V, White CL, Joachimiak LA, Diamond MI
eLife 2023 Jun 30;12
eLife 2023 Jun 30;12
APOBEC3B coordinates R-loop to promote replication stress and sensitize cancer cells to ATR/Chk1 inhibitors.
Zong C, Zhang Z, Gao L, He J, Wang Y, Li Q, Liu X, Yang J, Chen D, Huang R, Zheng G, Jin X, Wei W, Jia R, Shen J
Cell death & disease 2023 Jun 3;14(6):348
Cell death & disease 2023 Jun 3;14(6):348
CircHIPK3 negatively regulates autophagy by blocking VCP binding to the Beclin 1 complex in bladder cancer.
Wang C, Liu T, Wang J, Cheng C, Zhang Z, Zhang J, Huang H, Li Y
Discover oncology 2023 Jun 3;14(1):86
Discover oncology 2023 Jun 3;14(1):86
Palmitoylation at Residue C221 of Japanese Encephalitis Virus NS2A Protein Contributes to Viral Replication Efficiency and Virulence.
Ma X, Xia Q, Liu K, Wu Z, Li C, Xiao C, Dong N, Hameed M, Anwar MN, Li Z, Shao D, Li B, Qiu Y, Wei J, Ma Z
Journal of virology 2023 Jun 29;97(6):e0038223
Journal of virology 2023 Jun 29;97(6):e0038223
Circulating LPS from gut microbiota leverages stenosis-induced deep vein thrombosis in mice.
Liu C, Zhou Y, Gao H, Zhang Z, Zhou Y, Xu Z, Zhang C, Xu Z, Zheng H, Ma YQ
Thrombosis journal 2023 Jun 29;21(1):71
Thrombosis journal 2023 Jun 29;21(1):71
A core NRF2 gene set defined through comprehensive transcriptomic analysis predicts selective drug resistance and poor multi-cancer prognosis.
Luo G, Kumar H, Alridge K, Rieger S, Jiang E, Chan ER, Soliman A, Mahdi H, Letterio JJ
bioRxiv : the preprint server for biology 2023 Jun 29;
bioRxiv : the preprint server for biology 2023 Jun 29;
Down-regulation of the Smad signaling by circZBTB46 via the Smad2-PDLIM5 axis to inhibit type I collagen expression.
Yu J, Yan WZ, Zhang XH, Zheng B, Pan WS, Yang Z, Zhang H, Nie ZY, Ma Y, Bai Y, Zhang L, Feng DD, Wen JK
Journal of geriatric cardiology : JGC 2023 Jun 28;20(6):431-447
Journal of geriatric cardiology : JGC 2023 Jun 28;20(6):431-447
GATA zinc finger protein p66β promotes breast cancer cell migration by acting as a co-activator of Snail.
Zou X, Ma L, Zhang Y, Zhang Q, Xu C, Zhang D, Chu Y, Zhang J, Li M, Zhang H, Wang J, Peng C, Wei G, Wu Y, Hou Z, Jia H
Cell death & disease 2023 Jun 28;14(6):382
Cell death & disease 2023 Jun 28;14(6):382
Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration.
Sun L, Zhang X, Wu S, Liu Y, Guerrero-Juarez CF, Liu W, Huang J, Yao Q, Yin M, Li J, Ramos R, Liao Y, Wu R, Xia T, Zhang X, Yang Y, Li F, Heng S, Zhang W, Yang M, Tzeng CM, Ji C, Plikus MV, Gallo RL, Zhang LJ
Cell reports 2023 Jun 27;42(6):112647
Cell reports 2023 Jun 27;42(6):112647
The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-κB.
Fei X, Huang J, Li F, Wang Y, Shao Z, Dong L, Wu Y, Li B, Zhang X, Lv B, Zhao Y, Weng Q, Chen K, Zhang M, Yang S, Zhang C, Zhang M, Li W, Ying S, Sun Q, Chen Z, Shen H
Cell reports 2023 Jun 27;42(6):112586
Cell reports 2023 Jun 27;42(6):112586
The Benefits of Nanosized Magnesium Oxide in Fish Megalobrama amblycephala: Evidence in Growth Performance, Redox Defense, Glucose Metabolism, and Magnesium Homeostasis.
Zhang L, Liu Z, Deng Y, He C, Liu W, Li X
Antioxidants (Basel, Switzerland) 2023 Jun 27;12(7)
Antioxidants (Basel, Switzerland) 2023 Jun 27;12(7)
Notch mediates the glycolytic switch via PI3K/Akt signaling to support embryonic development.
Wang H, Liang W, Wang X, Zhan Y, Wang W, Yang L, Zhu Y
Cellular & molecular biology letters 2023 Jun 26;28(1):50
Cellular & molecular biology letters 2023 Jun 26;28(1):50
SIAH1/CTR9 axis promotes the epithelial-mesenchymal transition of hepatocellular carcinoma.
Liu Z, Luo P, Cao K, Hu Q, Hu B, Cui L, Wang X, Shi H, Zhang B, Wang R
Carcinogenesis 2023 Jun 24;44(4):304-316
Carcinogenesis 2023 Jun 24;44(4):304-316
Perturbation of endoplasmic reticulum proteostasis triggers tissue injury in the thyroid gland.
Zhang X, Young C, Liao XH, Refetoff S, Torres M, Tomer Y, Stefan-Lifshitz M, Zhang H, Larkin D, Fang D, Qi L, Arvan P
JCI insight 2023 Jun 22;8(12)
JCI insight 2023 Jun 22;8(12)
Ginsenoside Rk3 Regulates Nonalcoholic Steatohepatitis by Modulation of Intestinal Flora and the PI3K/AKT Signaling Pathway in C57BL/6 Mice.
Guo M, Zhu C, Fu R, Ma X, Duan Z, Fan D
Journal of agricultural and food chemistry 2023 Jun 21;71(24):9370-9380
Journal of agricultural and food chemistry 2023 Jun 21;71(24):9370-9380
C-X-C Motif Chemokine 3 Promotes the Inflammatory Response of Microglia after Escherichia coli-Induced Meningitis.
Qu X, Dou B, Yang R, Tan C, Chen H, Wang X
International journal of molecular sciences 2023 Jun 21;24(13)
International journal of molecular sciences 2023 Jun 21;24(13)
METTL16 promotes glycolytic metabolism reprogramming and colorectal cancer progression.
Wei W, Zhang ZY, Shi B, Cai Y, Zhang HS, Sun CL, Fei YF, Zhong W, Zhang S, Wang C, He B, Jiang GM, Wang H
Journal of experimental & clinical cancer research : CR 2023 Jun 20;42(1):151
Journal of experimental & clinical cancer research : CR 2023 Jun 20;42(1):151
Profiling the metabolome of uterine fluid for early detection of ovarian cancer.
Wang P, Ma J, Li W, Wang Q, Xiao Y, Jiang Y, Gu X, Wu Y, Dong S, Guo H, Li M
Cell reports. Medicine 2023 Jun 20;4(6):101061
Cell reports. Medicine 2023 Jun 20;4(6):101061
ULK1-mediated metabolic reprogramming regulates Vps34 lipid kinase activity by its lactylation.
Jia M, Yue X, Sun W, Zhou Q, Chang C, Gong W, Feng J, Li X, Zhan R, Mo K, Zhang L, Qian Y, Sun Y, Wang A, Zou Y, Chen W, Li Y, Huang L, Yang Y, Zhao Y, Cheng X
Science advances 2023 Jun 2;9(22):eadg4993
Science advances 2023 Jun 2;9(22):eadg4993
Chemo- and Diastereoselective Cycloisomerization/[2 + 3] Cycloaddition of Enynamides: Synthesis of Spiropyrazolines as Potential Anticancer Reagents.
Fang H, Li Y, Zhang L, Yan ZH, Ma K, Peng C, Huang W, Zhan G
The Journal of organic chemistry 2023 Jun 2;88(11):7311-7319
The Journal of organic chemistry 2023 Jun 2;88(11):7311-7319
Effects of Si-Miao-Yong-An decoction on myocardial I/R rats by regulating gut microbiota to inhibit LPS-induced TLR4/NF-κB signaling pathway.
Cui Y, Zhang F, Xu W, Li Z, Zou J, Gao P, Hu J
BMC complementary medicine and therapies 2023 Jun 2;23(1):180
BMC complementary medicine and therapies 2023 Jun 2;23(1):180
Oridonin promotes endoplasmic reticulum stress via TP53-repressed TCF4 transactivation in colorectal cancer.
Zhou F, Gao H, Shang L, Li J, Zhang M, Wang S, Li R, Ye L, Yang S
Journal of experimental & clinical cancer research : CR 2023 Jun 19;42(1):150
Journal of experimental & clinical cancer research : CR 2023 Jun 19;42(1):150
Biallelic variants in MAD2L1BP (p31(comet)) cause female infertility characterized by oocyte maturation arrest.
Huang L, Li W, Dai X, Zhao S, Xu B, Wang F, Jin RT, Luo L, Wu L, Jiang X, Cheng Y, Zou J, Xu C, Tong X, Fan HY, Zhao H, Bao J
eLife 2023 Jun 19;12
eLife 2023 Jun 19;12
Genetic lineage tracing reveals stellate cells as contributors to myofibroblasts in pancreas and islet fibrosis.
Wang J, Li T, Zhou Y, Wang X, Carvalho V, Ni C, Li W, Wang Q, Chen Y, Shang Z, Qiu S, Sun Z
iScience 2023 Jun 16;26(6):106988
iScience 2023 Jun 16;26(6):106988
Zhx2 maintains islet β-cell mass and function by transcriptionally regulating Pax6.
Ding L, Zhang Y, Wang Y, Wang Y, Tong Z, Li P, Chen C, Wang B, Yue X, Li C, Wu Z, Liang X, Ma C, Gao L
iScience 2023 Jun 16;26(6):106871
iScience 2023 Jun 16;26(6):106871
Cathepsin K promotes the proliferation of hepatocellular carcinoma cells through induction of SIAH1 ubiquitination and degradation.
Zhang C, Liu Z, Wang X, Zhang B, Cui L, Hu Q, Hu B, Cao K, Shan W, Shi H, Wang R
iScience 2023 Jun 16;26(6):106852
iScience 2023 Jun 16;26(6):106852
Aminosalicylates target GPR35, partly contributing to the prevention of DSS-induced colitis.
Otkur W, Wang J, Hou T, Liu F, Yang R, Li Y, Xiang K, Pei S, Qi H, Lin H, Zhou H, Zhang X, Piao HL, Liang X
European journal of pharmacology 2023 Jun 15;949:175719
European journal of pharmacology 2023 Jun 15;949:175719
ZDHHC2-Mediated AGK Palmitoylation Activates AKT-mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma.
Sun Y, Zhu L, Liu P, Zhang H, Guo F, Jin X
Cancer research 2023 Jun 15;83(12):2034-2051
Cancer research 2023 Jun 15;83(12):2034-2051
Subconjunctival Administration of Mesenchymal Stem Cells Alleviates Ocular Inflammation in a Murine Model of Corneal Alkali Burn.
Chen M, Chen X, Li X, Wang J, Wu J, Wang Q, Huang Y, Li Z, Wang L
Stem cells (Dayton, Ohio) 2023 Jun 15;41(6):592-602
Stem cells (Dayton, Ohio) 2023 Jun 15;41(6):592-602
Microglia activation mediates circadian rhythm disruption-induced cognitive impairment in mice.
Meng D, Yang M, Zhang H, Zhang L, Song H, Liu Y, Zeng Y, Yang B, Wang X, Chen Y, Liu R
Journal of neuroimmunology 2023 Jun 15;379:578102
Journal of neuroimmunology 2023 Jun 15;379:578102
Combination effects of amino acid transporter LAT1 inhibitor nanvuranlat and cytotoxic anticancer drug gemcitabine on pancreatic and biliary tract cancer cells.
Nishikubo K, Ohgaki R, Liu X, Okanishi H, Xu M, Endou H, Kanai Y
Cancer cell international 2023 Jun 15;23(1):116
Cancer cell international 2023 Jun 15;23(1):116
Baicalein Suppresses NLRP3 and AIM2 Inflammasome-Mediated Pyroptosis in Macrophages Infected by Mycobacterium tuberculosis via Induced Autophagy.
Ning B, Shen J, Liu F, Zhang H, Jiang X
Microbiology spectrum 2023 Jun 15;11(3):e0471122
Microbiology spectrum 2023 Jun 15;11(3):e0471122
Rapamycin Inhibits Osteoclastogenesis and Prevents LPS-Induced Alveolar Bone Loss by Oxidative Stress Suppression.
Feng C, Liu Y, Zhang BY, Zhang H, Shan FY, Li TQ, Zhao ZN, Wang XX, Zhang XY
ACS omega 2023 Jun 13;8(23):20739-20754
ACS omega 2023 Jun 13;8(23):20739-20754
Bioengineered Bacteriophage-Like Nanoparticles as RNAi Therapeutics to Enhance Radiotherapy against Glioblastomas.
Pang HH, Huang CY, Chen PY, Li NS, Hsu YP, Wu JK, Fan HF, Wei KC, Yang HW
ACS nano 2023 Jun 13;17(11):10407-10422
ACS nano 2023 Jun 13;17(11):10407-10422
Gastroprotective Effects of the Aqueous Extract of Finger Citron Pickled Products against Ethanol-Induced Gastric Damage: In Vitro and In Vivo Studies.
Chen X, Yang D, Wang Q, Zhou A
Foods (Basel, Switzerland) 2023 Jun 13;12(12)
Foods (Basel, Switzerland) 2023 Jun 13;12(12)
Discovery of a potent inhibitor of chaperone-mediated autophagy that targets the HSC70-LAMP2A interaction in non-small cell lung cancer cells.
Dong RF, Qin CJ, Yin Y, Han LL, Xiao CM, Wang KD, Wei RY, Xia YZ, Kong LY
British journal of pharmacology 2023 Jun 13;
British journal of pharmacology 2023 Jun 13;
Yi-Shen-Xie-Zhuo formula alleviates cisplatin-induced AKI by regulating inflammation and apoptosis via the cGAS/STING pathway.
Qi J, Luo Q, Zhang Q, Wu M, Zhang L, Qin L, Xue Q, Nie X
Journal of ethnopharmacology 2023 Jun 12;309:116327
Journal of ethnopharmacology 2023 Jun 12;309:116327
Antidepressive mechanisms of rhynchophylline in mice with chronic unpredictable stress-induced depression.
Liu EY, Yang CL, Tsai JC, Cheng HY, Peng WH
Journal of ethnopharmacology 2023 Jun 12;309:116302
Journal of ethnopharmacology 2023 Jun 12;309:116302
Ubiquitination of GRK2 Is Required for the β-Arrestin-Biased Signaling Pathway of Dopamine D2 Receptors to Activate ERK Kinases.
Liu H, Ma H, Zeng X, Wu C, Acharya S, Sudan SK, Zhang X
International journal of molecular sciences 2023 Jun 12;24(12)
International journal of molecular sciences 2023 Jun 12;24(12)
The synbiotic mixture of lactulose and Bacillus coagulans protects intestinal barrier dysfunction and apoptosis in weaned piglets challenged with lipopolysaccharide.
Zheng W, Zhao Z, Yang Y, Ding L, Yao W
Journal of animal science and biotechnology 2023 Jun 11;14(1):80
Journal of animal science and biotechnology 2023 Jun 11;14(1):80
EFFECT OF EXOSOMES DERIVED FROM BONE MARROW MESENCHYMAL STEM CELLS ON PROGRAMMED CELL DEATH IN BLAST-INDUCED LUNG INJURY IN RATS.
Deng M, He J, Hao C, Guo Y, Si H, Deng X, Zhang C, Li S, Yao S, Ren W, Yao W
Shock (Augusta, Ga.) 2023 Jun 1;59(6):955-965
Shock (Augusta, Ga.) 2023 Jun 1;59(6):955-965
MiR-24-3p/Dio3 axis is essential for BDE47 to induce local thyroid hormone disorder and neurotoxicity.
Liu M, Yu Z, Zhao Z, Yang F, Zhou M, Wang C, Tian X, Zhang B, Liang G, Liu X, Shao J
Toxicology 2023 Jun 1;491:153527
Toxicology 2023 Jun 1;491:153527
Dexamethasone enhances venetoclax-induced apoptosis in acute myeloid leukemia cells.
Wang H, Zhou J, Ma X, Jiao C, Chen E, Wu Z, Zhang Y, Pan M, Cui J, Luan C, Ge J
Medical oncology (Northwood, London, England) 2023 Jun 1;40(7):193
Medical oncology (Northwood, London, England) 2023 Jun 1;40(7):193
CM3-SII polysaccharide obtained from Cordyceps militaris ameliorates hyperlipidemia in heterozygous LDLR-deficient hamsters by modulating gut microbiota and NPC1L1 and PPARα levels.
Yu WQ, Wang XL, Ji HH, Miao M, Zhang BH, Li H, Zhang ZY, Ji CF, Guo SD
International journal of biological macromolecules 2023 Jun 1;239:124293
International journal of biological macromolecules 2023 Jun 1;239:124293
An O-GlcNAc transferase pathogenic variant linked to intellectual disability affects pluripotent stem cell self-renewal.
Omelková M, Fenger CD, Murray M, Hammer TB, Pravata VM, Bartual SG, Czajewski I, Bayat A, Ferenbach AT, Stavridis MP, van Aalten DMF
Disease models & mechanisms 2023 Jun 1;16(6)
Disease models & mechanisms 2023 Jun 1;16(6)
Tissue-resident CXCR4(+) macrophage as a poor prognosis signature promotes pancreatic ductal adenocarcinoma progression.
Liao Z, Ye L, Li T, Jin X, Lin X, Fei Q, Zhang H, Shi S, Yu X, Jin K, Wu W
International journal of cancer 2023 Jun 1;152(11):2396-2409
International journal of cancer 2023 Jun 1;152(11):2396-2409
Lymphocyte-Related Immunomodulatory Therapy with Siponimod (BAF-312) Improves Outcomes in Mice with Acute Intracerebral Hemorrhage.
Zhang Z, Li Y, Shi J, Zhu L, Dai Y, Fu P, Liu S, Hong M, Zhang J, Wang J, Jiang C
Aging and disease 2023 Jun 1;14(3):966-991
Aging and disease 2023 Jun 1;14(3):966-991
Curcumin preconditioning enhances the neuroprotective effects of olfactory mucosa-derived mesenchymal stem cells on experimental intracerebral hemorrhage.
Huang Y, Liu J, He J, Tan F, Lu M, Yuan F, Zhu X, Kong L
Heliyon 2023 Jul;9(7):e17874
Heliyon 2023 Jul;9(7):e17874
Peripheral immune cell death in sepsis based on bulk RNA and single-cell RNA sequencing.
Liu S, Duan C, Xie J, Zhang J, Luo X, Wang Q, Liang X, Zhao X, Zhuang R, Zhao W, Yin W
Heliyon 2023 Jul;9(7):e17764
Heliyon 2023 Jul;9(7):e17764
The role of TRPV4 in the regulation of retinal ganglion cells apoptosis in rat and mouse.
Wang Y, Zhang W, Xu G, Shi C, Wang X, Qu J, Wang H, Liu C
Heliyon 2023 Jul;9(7):e17583
Heliyon 2023 Jul;9(7):e17583
Natural Oncolysis of Enterovirus 71 in Antitumor Therapy of Colorectal Cancer.
Ruan Z, Chi J, Kong Y, Li C, Ruan X, Zhou X, Chen Y, Li Y, Luo Z
Advanced biology 2023 Jul;7(7):e2200336
Advanced biology 2023 Jul;7(7):e2200336
Targeting ACYP1-mediated glycolysis reverses lenvatinib resistance and restricts hepatocellular carcinoma progression.
Wang S, Zhou L, Ji N, Sun C, Sun L, Sun J, Du Y, Zhang N, Li Y, Liu W, Lu W
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2023 Jul;69:100976
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2023 Jul;69:100976
Intermittent Fasting Alleviates Non-Alcoholic Steatohepatitis by Regulating Bile Acid Metabolism and Promoting Fecal Bile Acid Excretion in High-Fat and High-Cholesterol Diet Fed Mice.
Lin X, Zhu X, Xin Y, Zhang P, Xiao Y, He T, Guo H
Molecular nutrition & food research 2023 Jul;67(14):e2200595
Molecular nutrition & food research 2023 Jul;67(14):e2200595
Advanced glycation end products promote the progression of chronic kidney diseases by targeting calpain 6.
Zhang Y, Han H, Qian Y, Wang Q, Jiang M
Amino acids 2023 Jul;55(7):903-912
Amino acids 2023 Jul;55(7):903-912
MLL4 Regulates the Progression of Non-Small-Cell Lung Cancer by Regulating the PI3K/AKT/SOX2 Axis.
Yang Y, Qiu R, Weng Q, Xu Z, Song J, Zhao S, Meng M, Zhang D, Kong C, Wang H, Xu M, Zhao Z, Ji J
Cancer research and treatment 2023 Jul;55(3):778-803
Cancer research and treatment 2023 Jul;55(3):778-803
RNA-binding Protein QKI Inhibits Osteogenic Differentiation Via Suppressing Wnt Pathway.
Yan Z, Ruan B, Wang S, Du T, Shao X, Chen G, Wang L, Zhai D, Zhu S, Lu Z, Cao X
Archives of medical research 2023 Jul;54(5):102853
Archives of medical research 2023 Jul;54(5):102853
Sevoflurane-induced P300 promotes neuron apoptosis via Sp1/CDK9 pathway.
Zhou X, Liu C, Xia D
Clinical and experimental pharmacology & physiology 2023 Jul;50(7):541-553
Clinical and experimental pharmacology & physiology 2023 Jul;50(7):541-553
mGluR5 in hippocampal CA1 pyramidal neurons mediates stress-induced anxiety-like behavior.
Li X, Du ZJ, Xu JN, Liang ZM, Lin S, Chen H, Li SJ, Li XW, Yang JM, Gao TM
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2023 Jul;48(8):1164-1174
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2023 Jul;48(8):1164-1174
Hypoxia-Preconditioned Bone Marrow Mesenchymal Stem Cells Improved Cerebral Collateral Circulation and Stroke Outcome in Mice.
Tian H, Yang X, Zhao J, Liu X, Liu X, Cai Y, Wehbe A, Ding Y, Yu S, Wei L, Liu L
Arteriosclerosis, thrombosis, and vascular biology 2023 Jul;43(7):1281-1294
Arteriosclerosis, thrombosis, and vascular biology 2023 Jul;43(7):1281-1294
The choleretic role of tauroursodeoxycholic acid exacerbates alpha-naphthylisothiocyanate induced cholestatic liver injury through the FXR/BSEP pathway.
Zhao J, Song G, Weng F, Li Y, Zou B, Jin J, Yan D, Sun X, Liu C, Qiu FR
Journal of applied toxicology : JAT 2023 Jul;43(7):1095-1103
Journal of applied toxicology : JAT 2023 Jul;43(7):1095-1103
USP13 deubiquitinates and stabilizes cyclin D1 to promote gastric cancer cell cycle progression and cell proliferation.
Ma C, Wang D, Tian Z, Gao W, Zang Y, Qian L, Xu X, Jia J, Liu Z
Oncogene 2023 Jul;42(29):2249-2262
Oncogene 2023 Jul;42(29):2249-2262
miR-101-5p suppresses trophoblast cell migration and invasion via modulating the DUSP6-ERK1/2 axis in preeclampsia.
Xu J, Wang J, Chen M, Chao B, He J, Bai Y, Luo X, Liu H, Xie L, Tao Y, Qi H, Luo X
Journal of assisted reproduction and genetics 2023 Jul;40(7):1597-1610
Journal of assisted reproduction and genetics 2023 Jul;40(7):1597-1610
Effect of peroxiredoxin 1 on the regulation of trophoblast function by affecting autophagy and oxidative stress in preeclampsia.
Zhou M, Guo J, Li S, Li A, Fang Z, Zhao M, Zhang M, Wang X
Journal of assisted reproduction and genetics 2023 Jul;40(7):1573-1587
Journal of assisted reproduction and genetics 2023 Jul;40(7):1573-1587
SLC25A22 as a Key Mitochondrial Transporter Against Ferroptosis by Producing Glutathione and Monounsaturated Fatty Acids.
Liu Y, Wang Y, Lin Z, Kang R, Tang D, Liu J
Antioxidants & redox signaling 2023 Jul;39(1-3):166-185
Antioxidants & redox signaling 2023 Jul;39(1-3):166-185
HDAC inhibitor chidamide overcomes drug resistance in chronic myeloid leukemia with the T315i mutation through the Akt-autophagy pathway.
Yin L, Zhang Q, Xie S, Cheng Z, Li R, Zhu H, Yu Q, Yuan H, Wang C, Peng H, Zhang G
Human cell 2023 Jul;36(4):1564-1577
Human cell 2023 Jul;36(4):1564-1577
Cathepsin B S-nitrosylation promotes ADAR1-mediated editing of its own mRNA transcript via an ADD1/MATR3 regulatory axis.
Lin Z, Zhao S, Li X, Miao Z, Cao J, Chen Y, Shi Z, Zhang J, Wang D, Chen S, Wang L, Gu A, Chen F, Yang T, Sun K, Han Y, Xie L, Chen H, Ji Y
Cell research 2023 Jul;33(7):546-561
Cell research 2023 Jul;33(7):546-561
Absorbable suture knots on the supraspinatus tendon prevent adverse effects of nonabsorbable suture knots in a rat model.
Ben H, Luo C, Cheng J, Zeng CH, Zhou Y, Jeon IH, Sun Y
Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA 2023 Jul;31(7):2572-2580
Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA 2023 Jul;31(7):2572-2580
The deubiquitylating enzyme USP35 restricts regulated cell death to promote survival of renal clear cell carcinoma.
Wang S, Wang T, Zhang X, Cheng S, Chen C, Yang G, Wang F, Wang R, Zhang Q, Yang D, Zhang Y, Liu S, Qin H, Liu Q, Liu H
Cell death and differentiation 2023 Jul;30(7):1757-1770
Cell death and differentiation 2023 Jul;30(7):1757-1770
The deubiquitinase USP28 maintains the expression of the transcription factor MYCN and is essential in neuroblastoma cells.
Li J, Peng J, Wu L, Shen X, Zhen X, Zhang Y, Ma H, Xu Y, Xiong Q, Zhu Q, Zhang P
The Journal of biological chemistry 2023 Jul;299(7):104856
The Journal of biological chemistry 2023 Jul;299(7):104856
Nutrient-dependent regulation of β-cell proinsulin content.
Xu X, Arunagiri A, Alam M, Haataja L, Evans CR, Zhao I, Castro-Gutierrez R, Russ HA, Demangel C, Qi L, Tsai B, Liu M, Arvan P
The Journal of biological chemistry 2023 Jul;299(7):104836
The Journal of biological chemistry 2023 Jul;299(7):104836
Palmitic acid-induced ferroptosis via CD36 activates ER stress to break calcium-iron balance in colon cancer cells.
Kuang H, Sun X, Liu Y, Tang M, Wei Y, Shi Y, Li R, Xiao G, Kang J, Wang F, Peng J, Xu H, Zhou F
The FEBS journal 2023 Jul;290(14):3664-3687
The FEBS journal 2023 Jul;290(14):3664-3687
Radiation resistance of cancer cells caused by mitochondrial dysfunction depends on SIRT3-mediated mitophagy.
Wei Y, Xiao G, Xu H, Sun X, Shi Y, Wang F, Kang J, Peng J, Zhou F
The FEBS journal 2023 Jul;290(14):3629-3645
The FEBS journal 2023 Jul;290(14):3629-3645
Pemetrexed induces ROS generation and cellular senescence by attenuating TS-mediated thymidylate metabolism to reverse gefitinib resistance in NSCLC.
Chen Y, Zhang C, Jin S, Li J, Dai J, Zhang Z, Guo R
Journal of cellular and molecular medicine 2023 Jul;27(14):2032-2044
Journal of cellular and molecular medicine 2023 Jul;27(14):2032-2044
RBM25 induces trophoblast epithelial-mesenchymal transition and preeclampsia disorder by enhancing the positive feedback loop between Grhl2 and RBM25.
Zhang J, Chen WQ, Yang K, Wang ZX, Sun DL, Peng YY, Yu M, Wang SX, Guo Q
Experimental biology and medicine (Maywood, N.J.) 2023 Jul;248(14):1267-1277
Experimental biology and medicine (Maywood, N.J.) 2023 Jul;248(14):1267-1277
Neotuberostemonine and tuberostemonine ameliorate pulmonary fibrosis through suppressing TGF-β and SDF-1 secreted by macrophages and fibroblasts via the PI3K-dependent AKT and ERK pathways.
Fu S, Song X, Hu Y, Zhu Q, Lv X, Tang X, Zhang M
Chinese journal of natural medicines 2023 Jul;21(7):527-539
Chinese journal of natural medicines 2023 Jul;21(7):527-539
Eucommia lignans alleviate the progression of diabetic nephropathy through mediating the AR/Nrf2/HO-1/AMPK axis in vivo and in vitro.
Huang Q, Zhang Y, Jiang Y, Huang L, Liu Q, Ouyang D
Chinese journal of natural medicines 2023 Jul;21(7):516-526
Chinese journal of natural medicines 2023 Jul;21(7):516-526
Membrane-dependent actin polymerization mediated by the Legionella pneumophila effector protein MavH.
Zhang Q, Wan M, Kudryashova E, Kudryashov DS, Mao Y
PLoS pathogens 2023 Jul;19(7):e1011512
PLoS pathogens 2023 Jul;19(7):e1011512
Bile duct ligation increased dopamine levels in the cerebral cortex of rats partly due to induction of tyrosine hydroxylase.
Kong W, Sun X, Yu S, Liu P, Zheng X, Zhang J, Zhu L, Jiang T, Jin M, Gao J, Fan X, Liu X, Liu L
British journal of pharmacology 2023 Jul;180(13):1690-1709
British journal of pharmacology 2023 Jul;180(13):1690-1709
Emodin attenuates inflammation and demyelination in experimental autoimmune encephalomyelitis.
Cui YR, Bu ZQ, Yu HY, Yan LL, Feng J
Neural regeneration research 2023 Jul;18(7):1535-1541
Neural regeneration research 2023 Jul;18(7):1535-1541
Betulinic acid mitigates zearalenone-induced liver injury by ERS/MAPK/Nrf2 signaling pathways in mice.
Wu J, Li J, Wu Y, Yang M, Chen Y, Wang N, Wang J, Yuan Z, Yi J, Yang C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113811
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113811
ACC010, a novel BRD4 inhibitor, synergized with homoharringtonine in acute myeloid leukemia with FLT3-ITD.
Qian Y, Zhang X, Mao S, Wei W, Lin X, Ling Q, Ye W, Li F, Pan J, Zhou Y, Zhao Y, Huang X, Huang J, Tong H, Sun J, Jin J
Molecular oncology 2023 Jul;17(7):1402-1418
Molecular oncology 2023 Jul;17(7):1402-1418
Resveratrol Promotes Gluconeogenesis by Inhibiting SESN2-mTORC2-AKT Pathway in Calf Hepatocytes.
Wang G, Qin S, Geng H, Zheng Y, Li R, Xia C, Chen L, Yao J, Deng L
The Journal of nutrition 2023 Jul;153(7):1930-1943
The Journal of nutrition 2023 Jul;153(7):1930-1943
Targeting NAD metabolism regulates extracellular adenosine levels to improve the cytotoxicity of CD8+ effector T cells in the tumor microenvironment of gastric cancer.
Liu HY, Wang FH, Liang JM, Xiang YY, Liu SH, Zhang SW, Zhu CM, He YL, Zhang CH
Journal of cancer research and clinical oncology 2023 Jul;149(7):2743-2756
Journal of cancer research and clinical oncology 2023 Jul;149(7):2743-2756
Alpinia oxyphylla Miq. volatile oil ameliorates depressive behaviors and inhibits neuroinflammation in CUMS-exposed mice by inhibiting the TLR4-medicated MyD88/NF-κB signaling pathway.
Wu B, Gan A, Wang R, Lin F, Yan T, Jia Y
Journal of chemical neuroanatomy 2023 Jul;130:102270
Journal of chemical neuroanatomy 2023 Jul;130:102270
rTMS treatment for abrogating intracerebral hemorrhage-induced brain parenchymal metabolite clearance dysfunction in male mice by regulating intracranial lymphatic drainage.
Liu Y, Liu X, Sun P, Li J, Nie M, Gong J, He A, Zhao M, Yang C, Wang Z
Brain and behavior 2023 Jul;13(7):e3062
Brain and behavior 2023 Jul;13(7):e3062
Suramin ameliorates osteoarthritis by acting on the Nrf2/HO-1 and NF-κB signaling pathways in chondrocytes and promoting M2 polarization in macrophages.
Shen PC, Huang SH, Liu ZM, Lu CC, Chou SH, Tien YC
International immunopharmacology 2023 Jul;120:110295
International immunopharmacology 2023 Jul;120:110295
Ergolide covalently binds NLRP3 and inhibits NLRP3 inflammasome-mediated pyroptosis.
Ren M, Chen J, Xu H, Li W, Wang T, Chi Z, Lin Y, Zhang A, Chen G, Wang X, Sun X, Liang G, Wang J, Luo W
International immunopharmacology 2023 Jul;120:110292
International immunopharmacology 2023 Jul;120:110292
Stromal cell-derived small extracellular vesicles enhance radioresistance of prostate cancer cells via interleukin-8-induced autophagy.
Wang X, Xu F, Kou H, Zheng Y, Yang J, Xu Z, Fang Y, Sun W, Zhu S, Jiang Q, Wei X, Xu Y
Journal of extracellular vesicles 2023 Jul;12(7):e12342
Journal of extracellular vesicles 2023 Jul;12(7):e12342
COLEC10 Induces Endoplasmic Reticulum Stress by Occupying GRP78 and Inhibits Hepatocellular Carcinoma.
Cai MN, Chen DM, Xiao LX, Li SS, Liao CH, Li J, Huang ZX, Wang JL, Gu YR, Gu L, Huang YH, Lian YF
Laboratory investigation; a journal of technical methods and pathology 2023 Jul;103(7):100130
Laboratory investigation; a journal of technical methods and pathology 2023 Jul;103(7):100130
Targeting macrophagic PIM-1 alleviates osteoarthritis by inhibiting NLRP3 inflammasome activation via suppressing mitochondrial ROS/Cl(-) efflux signaling pathway.
Zhang Z, Xie S, Qian J, Gao F, Jin W, Wang L, Yan L, Chen H, Yao W, Li M, Wang X, Zhu L
Journal of translational medicine 2023 Jul 8;21(1):452
Journal of translational medicine 2023 Jul 8;21(1):452
Synergistic Effect of Treatment with Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus and Lipopolysaccharide on the Inflammatory Response of Porcine Pulmonary Microvascular Endothelial Cells.
Yao X, Dai W, Yang S, Wang Z, Zhang Q, Meng Q, Zhang T
Viruses 2023 Jul 8;15(7)
Viruses 2023 Jul 8;15(7)
Abnormal Expression of Prolyl Oligopeptidase (POP) and Its Catalytic Products Ac-SDKP Contributes to the Ovarian Fibrosis Change in Polycystic Ovary Syndrome (PCOS) Mice.
Han S, Wang S, Fan X, Chen M, Wang X, Huang Y, Zhang H, Ma Y, Wang J, Zhang C
Biomedicines 2023 Jul 7;11(7)
Biomedicines 2023 Jul 7;11(7)
Gasdermin D licenses MHCII induction to maintain food tolerance in small intestine.
He K, Wan T, Wang D, Hu J, Zhou T, Tao W, Wei Z, Lu Q, Zhou R, Tian Z, Flavell RA, Zhu S
Cell 2023 Jul 6;186(14):3033-3048.e20
Cell 2023 Jul 6;186(14):3033-3048.e20
Microglial-to-neuronal CCR5 signaling regulates autophagy in neurodegeneration.
Festa BP, Siddiqi FH, Jimenez-Sanchez M, Won H, Rob M, Djajadikerta A, Stamatakou E, Rubinsztein DC
Neuron 2023 Jul 5;111(13):2021-2037.e12
Neuron 2023 Jul 5;111(13):2021-2037.e12
Alphavirus-induced transcriptional and translational shutoffs play major roles in blocking the formation of stress granules.
Palchevska O, Dominguez F, Frolova EI, Frolov I
bioRxiv : the preprint server for biology 2023 Jul 5;
bioRxiv : the preprint server for biology 2023 Jul 5;
SFRP1 Expression is Inversely Associated With Metastasis Formation in Canine Mammary Tumours.
Seitz J, Bilsland A, Puget C, Baasner I, Klopfleisch R, Stein T
Journal of mammary gland biology and neoplasia 2023 Jul 4;28(1):15
Journal of mammary gland biology and neoplasia 2023 Jul 4;28(1):15
CircRNA-02191 regulating unsaturated fatty acid synthesis by adsorbing miR-145 to enhance CD36 expression in bovine mammary gland.
Chen Z, Wang Y, Wang K, Zhang Z, Han M, Li G, Zhang B, Yang Y, Loor JJ, Yang Z, Zhong F, Dai R, Wang M
International journal of biological macromolecules 2023 Jul 31;244:125306
International journal of biological macromolecules 2023 Jul 31;244:125306
Exosomes from tannic acid-stimulated macrophages accelerate wound healing through miR-221-3p mediated fibroblasts migration by targeting CDKN1b.
Song X, Chen Y, Chen X, Zhao X, Zou Y, Li L, Zhou X, Li M, Zhang D, Ye G, Jia R, Yin Z
International journal of biological macromolecules 2023 Jul 31;244:125088
International journal of biological macromolecules 2023 Jul 31;244:125088
Long non-coding RNA PVT1 regulates atherosclerosis progression via the microRNA-106b-5p/ACSL4 axis.
Zhang M, Yu Z, Zhao L, Luo H
Biochemical and biophysical research communications 2023 Jul 30;667:170-179
Biochemical and biophysical research communications 2023 Jul 30;667:170-179
FBXL4 ubiquitin ligase deficiency promotes mitophagy by elevating NIX levels.
Elcocks H, Brazel AJ, McCarron KR, Kaulich M, Husnjak K, Mortiboys H, Clague MJ, Urbé S
The EMBO journal 2023 Jul 3;42(13):e112799
The EMBO journal 2023 Jul 3;42(13):e112799
circACTA2 inhibits NLRP3 inflammasome-mediated inflammation via interacting with NF-κB in vascular smooth muscle cells.
Bai Y, Zhang L, Zheng B, Zhang X, Zhang H, Zhao A, Yu J, Yang Z, Wen J
Cellular and molecular life sciences : CMLS 2023 Jul 27;80(8):229
Cellular and molecular life sciences : CMLS 2023 Jul 27;80(8):229
Single-cell transcriptomics reveals intestinal cell heterogeneity and identifies Ep300 as a potential therapeutic target in mice with acute liver failure.
Yin J, Zhao Z, Huang J, Xiao Y, Rehmutulla M, Zhang B, Zhang Z, Xiang M, Tong Q, Zhang Y
Cell discovery 2023 Jul 25;9(1):77
Cell discovery 2023 Jul 25;9(1):77
αKG-driven RNA polymerase II transcription of cyclin D1 licenses malic enzyme 2 to promote cell-cycle progression.
Yang Y, Zhang Z, Li W, Si Y, Li L, Du W
Cell reports 2023 Jul 25;42(7):112770
Cell reports 2023 Jul 25;42(7):112770
Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2.
Wu Z, Cao Z, Yao H, Yan X, Xu W, Zhang M, Jiao Z, Zhang Z, Chen J, Liu Y, Zhang M, Wang D
Cell reports 2023 Jul 25;42(7):112693
Cell reports 2023 Jul 25;42(7):112693
Astrocytic α4-containing nAChR signaling in the hippocampus governs the formation of temporal association memory.
Ma W, Si T, Wang Z, Wen P, Zhu Z, Liu Q, Wang J, Xu F, Li Q
Cell reports 2023 Jul 25;42(7):112674
Cell reports 2023 Jul 25;42(7):112674
SIRT3 ameliorates diabetes-associated cognitive dysfunction via regulating mitochondria-associated ER membranes.
Chang Y, Wang C, Zhu J, Zheng S, Sun S, Wu Y, Jiang X, Li L, Ma R, Li G
Journal of translational medicine 2023 Jul 22;21(1):494
Journal of translational medicine 2023 Jul 22;21(1):494
Iron induces B cell pyroptosis through Tom20-Bax-caspase-gasdermin E signaling to promote inflammation post-spinal cord injury.
Wu C, Wang L, Chen S, Shi L, Liu M, Tu P, Sun J, Zhao R, Zhang Y, Wang J, Pan Y, Ma Y, Guo Y
Journal of neuroinflammation 2023 Jul 22;20(1):171
Journal of neuroinflammation 2023 Jul 22;20(1):171
LILRB2/PirB mediates macrophage recruitment in fibrogenesis of nonalcoholic steatohepatitis.
Li DP, Huang L, Kan RR, Meng XY, Wang SY, Zou HJ, Guo YM, Luo PQ, Pan LM, Xiang YX, Mao BB, Xie YY, Wang ZH, Yang M, He R, Yang Y, Liu ZL, Xie JH, Ma DL, Zhang BP, Shao SY, Chen X, Xu SM, He WT, Li WJ, Chen Y, Yu XF
Nature communications 2023 Jul 22;14(1):4436
Nature communications 2023 Jul 22;14(1):4436
Dephosphorylation of Six2Y129 protects tyrosine hydroxylase-positive cells in SNpc by regulating TEA domain 1 expression.
Zhang CT, Qin DL, Cao XY, Kan JS, Huang XX, Gao DS, Gao J
iScience 2023 Jul 21;26(7):107049
iScience 2023 Jul 21;26(7):107049
ZIC2 induces pro-tumor macrophage polarization in nasopharyngeal carcinoma by activating the JUNB/MCSF axis.
Liu Q, Yang T, Zhang Y, Hu ZD, Liu YM, Luo YL, Liu SX, Zhang H, Zhong Q
Cell death & disease 2023 Jul 21;14(7):455
Cell death & disease 2023 Jul 21;14(7):455
Novel Protein C6ORF120 Promotes Apoptosis through Mitochondria-dependent Pathway in CD4 (+)T Lymphocytes.
Liu H, Wang X, Wang P, Wang YQ, Yi YY, Li X
Biomedical and environmental sciences : BES 2023 Jul 20;36(7):639-643
Biomedical and environmental sciences : BES 2023 Jul 20;36(7):639-643
HnRNP A1 Suppresses the Odontogenic Differentiation and the Inclusion of RUNX2 Exon 5 of Dental Mesenchymal Cells.
Zhang Y, Huang J, Yan L, Jia R, Guo J
Frontiers in bioscience (Landmark edition) 2023 Jul 19;28(7):139
Frontiers in bioscience (Landmark edition) 2023 Jul 19;28(7):139
Combined surface functionalization of MSC membrane and PDA inhibits neurotoxicity induced by Fe(3)O(4) in mice based on apoptosis and autophagy through the ASK1/JNK signaling pathway.
Li Y, Liu T, Li X, Yang M, Liu T, Bao J, Jiang M, Hu L, Wang Y, Shao P, Jiang J
Aging 2023 Jul 19;15(14):6933-6949
Aging 2023 Jul 19;15(14):6933-6949
Transcriptional analysis of the expression and prognostic value of lipid droplet-localized proteins in hepatocellular carcinoma.
Zhang Y, Liang X, Lian Q, Liu L, Zhang B, Dong Z, Liu K
BMC cancer 2023 Jul 18;23(1):677
BMC cancer 2023 Jul 18;23(1):677
Structures of p53/BCL-2 complex suggest a mechanism for p53 to antagonize BCL-2 activity.
Wei H, Wang H, Wang G, Qu L, Jiang L, Dai S, Chen X, Zhang Y, Chen Z, Li Y, Guo M, Chen Y
Nature communications 2023 Jul 18;14(1):4300
Nature communications 2023 Jul 18;14(1):4300
Selective activation of AKAP150/TRPV1 in ventrolateral periaqueductal gray GABAergic neurons facilitates conditioned place aversion in male mice.
Bai X, Zhang K, Ou C, Nie B, Zhang J, Huang Y, Zhang Y, Huang J, Ouyang H, Cao M, Huang W
Communications biology 2023 Jul 17;6(1):742
Communications biology 2023 Jul 17;6(1):742
COPS3 inhibition promotes cell proliferation blockage and anoikis via regulating PFKFB3 in osteosarcoma cancer cells.
Zhang F, Li Q, Zhang Y, Li N, Rao M, Li S, Ai Z, Yan S, Tian Z
European journal of pharmacology 2023 Jul 15;951:175799
European journal of pharmacology 2023 Jul 15;951:175799
Proteomic analysis reveals the mechanisms of the astaxanthin suppressed foam cell formation.
Liu A, Li R, Zaaboul F, He M, Li X, Shi J, Liu Y, Xu YJ
Life sciences 2023 Jul 15;325:121774
Life sciences 2023 Jul 15;325:121774
An animal model induced by bilateral cavernous nerve crushing mimics post-radical prostatectomy erectile dysfunction in old rats.
Ge Y, Hu D, Xi Y, Wang H, Xia T, Chen J, Pu X, Xiao H
Life sciences 2023 Jul 15;325:121767
Life sciences 2023 Jul 15;325:121767
Resveratrol plays an anti-fibrotic and anti-autophagy role by stimulating miR-192-5p expression in urethral fibrosis.
Lv J, Zhang R, Li D, Liu Y
Functional & integrative genomics 2023 Jul 14;23(3):241
Functional & integrative genomics 2023 Jul 14;23(3):241
N-Acetylaspartate Drives Oligodendroglial Differentiation via Histone Deacetylase Activation.
Dominicis A, Del Giovane A, Torreggiani M, Recchia AD, Ciccarone F, Ciriolo MR, Ragnini-Wilson A
Cells 2023 Jul 14;12(14)
Cells 2023 Jul 14;12(14)
JMJD8 regulates neuropathic pain by affecting spinal cord astrocyte differentiation.
Li Y, Zhang Y, Zhou Z, Yi L, Ji F, Zhang K, Zhang Y, Xu H
Neuroscience letters 2023 Jul 13;809:137307
Neuroscience letters 2023 Jul 13;809:137307
Identification of residues critical for the extension of Munc18-1 domain 3a.
Wang X, Gong J, Zhu L, Chen H, Jin Z, Mo X, Wang S, Yang X, Ma C
BMC biology 2023 Jul 13;21(1):158
BMC biology 2023 Jul 13;21(1):158
Fetal factors disrupt placental and maternal iron homeostasis in murine β-thalassemia.
Yu Y, Woloshun RR, Lee JK, Ebea PO, Zhu S, Nemeth E, Garrick LM, Garrick MD, Collins JF
Blood 2023 Jul 13;142(2):185-196
Blood 2023 Jul 13;142(2):185-196
Activation of the IKK2-NFκB pathway in VSMCs inhibits calcified vascular stiffness in CKD by reducing the secretion of calcifying extracellular vesicles.
Miyazaki-Anzai S, Masuda M, Keenan AL, Shiozaki Y, Miyazaki M
bioRxiv : the preprint server for biology 2023 Jul 12;
bioRxiv : the preprint server for biology 2023 Jul 12;
CXCR4-Targeted Necrosis-Inducing Peptidomimetic for Treating Breast Cancer.
Akonnor A, Makise M, Kuniyasu A
ACS omega 2023 Jul 11;8(27):24467-24476
ACS omega 2023 Jul 11;8(27):24467-24476
Embryonic Exposure to UV-328 Impairs the Cell Cycle in Zebrafish (Danio rerio) by Inhibiting the p38 MAPK/p53/Gadd45a Signaling Pathway.
Zhang L, Shen L, Huang Y, Cui S, Zhao Q, Zhang C, Zhuang S, Jiang G
Environmental science & technology 2023 Jul 11;57(27):9965-9974
Environmental science & technology 2023 Jul 11;57(27):9965-9974
Protective Effect of Water-Soluble Acacetin Prodrug on APAP-Induced Acute Liver Injury Is Associated with Upregulation of PPARγ and Alleviation of ER Stress.
Miao J, Yao S, Sun H, Jiang Z, Gao Z, Xu J, Chen K
International journal of molecular sciences 2023 Jul 11;24(14)
International journal of molecular sciences 2023 Jul 11;24(14)
Lysophosphatidic acid is associated with oocyte maturation by enhancing autophagy via PI3K-AKT-mTOR signaling pathway in granulosa cells.
Liu J, Wang C
Journal of ovarian research 2023 Jul 11;16(1):137
Journal of ovarian research 2023 Jul 11;16(1):137
Antiandrogen treatment induces stromal cell reprogramming to promote castration resistance in prostate cancer.
Wang H, Li N, Liu Q, Guo J, Pan Q, Cheng B, Xu J, Dong B, Yang G, Yang B, Wang X, Gu Y, Zhang G, Lian Y, Zhang W, Zhang M, Li T, Zang Y, Tan M, Li Q, Wang X, Yu Z, Jiang J, Huang H, Qin J
Cancer cell 2023 Jul 10;41(7):1345-1362.e9
Cancer cell 2023 Jul 10;41(7):1345-1362.e9
A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy.
Southwell N, Primiano G, Nadkarni V, Attarwala N, Beattie E, Miller D, Alam S, Liparulo I, Shurubor YI, Valentino ML, Carelli V, Servidei S, Gross SS, Manfredi G, Chen Q, D'Aurelio M
EMBO molecular medicine 2023 Jul 10;15(7):e16951
EMBO molecular medicine 2023 Jul 10;15(7):e16951
γ-Bungarotoxin impairs the vascular endothelial barrier function by inhibiting integrin α5.
Chen W, Yu H, Sun C, Dong M, Zhao N, Wang Y, Yu K, Zhang J, Xu N, Liu W
Toxicology letters 2023 Jul 1;383:177-191
Toxicology letters 2023 Jul 1;383:177-191
Periplocin inhibits hepatocellular carcinoma progression and reduces the recruitment of MDSCs through AKT/NF-κB pathway.
Lin JP, Huang MH, Sun ZT, Chen L, Lei YH, Huang YQ, Qi M, Fan SR, Chen SG, Chung CW, Chan MC, Liu JS, Hu M, Chen MF, Ye WC, Chen YY, Deng LJ
Life sciences 2023 Jul 1;324:121715
Life sciences 2023 Jul 1;324:121715
Lysine crotonylation of SERCA2a correlates to cardiac dysfunction and arrhythmia in Sirt1 cardiac-specific knockout mice.
Chen HX, Wang XC, Hou HT, Wang J, Yang Q, Chen YL, Chen HZ, He GW
International journal of biological macromolecules 2023 Jul 1;242(Pt 4):125151
International journal of biological macromolecules 2023 Jul 1;242(Pt 4):125151
Angelica sinensis aboveground part polysaccharide and its metabolite 5-MT ameliorate colitis via modulating gut microbiota and TLR4/MyD88/NF-κB pathway.
Zou YF, Li CY, Fu YP, JiZe XP, Zhao YZ, Peng X, Wang JY, Yin ZQ, Li YP, Song X, Li LX, Zhao XH, Feng B, Huang C, Ye G, Tang HQ, Chen J, Li R, Chen XF, Tian ML
International journal of biological macromolecules 2023 Jul 1;242(Pt 1):124689
International journal of biological macromolecules 2023 Jul 1;242(Pt 1):124689
An enzyme-instructed self-assembly system induces tumor acidosis via sequential-dual effect for cancer selective therapy.
Zhang H, Wang Z, Gao T, Wang Z, Ren C, Liu J
Acta biomaterialia 2023 Jul 1;164:447-457
Acta biomaterialia 2023 Jul 1;164:447-457
Integrating network pharmacology and experimental verification to explore the pharmacological mechanisms of asparagus against polycystic ovary syndrome.
Xing J, Luo X, Jia K, Liu S, Chen S, Qiao G, Zhang C, Yi J
Journal of ovarian research 2023 Jul 1;16(1):128
Journal of ovarian research 2023 Jul 1;16(1):128
KLF6 alleviates hepatic ischemia-reperfusion injury by inhibiting autophagy.
Li J, Yu D, He C, Yu Q, Huo Z, Zhang Y, Zhang S
Cell death & disease 2023 Jul 1;14(7):393
Cell death & disease 2023 Jul 1;14(7):393
Heme oxygenase-1 protects against PM2.5 induced endothelial dysfunction through inhibition of HIF1α.
Xu H, Wen Q, Xu X, Yu D, Liu Z, Zhang C, Zhang X, Ma J, Zhao H, Song L
Environmental toxicology and pharmacology 2023 Jan;97:104024
Environmental toxicology and pharmacology 2023 Jan;97:104024
Direct administration of mesenchymal stem cell-derived mitochondria improves cardiac function after infarction via ameliorating endothelial senescence.
Liang X, Zhang Y, Lin F, Li M, Li X, Chen Y, Liu J, Meng Q, Ma X, Wang E, Wei L, He Z, Fan H, Zhou X, Ding Y, Liu Z
Bioengineering & translational medicine 2023 Jan;8(1):e10365
Bioengineering & translational medicine 2023 Jan;8(1):e10365
Tanshinone functions as a coenzyme that confers gain of function of NQO1 to suppress ferroptosis.
Wang TX, Duan KL, Huang ZX, Xue ZA, Liang JY, Dang Y, Zhang A, Xiong Y, Ding C, Guan KL, Yuan HX
Life science alliance 2023 Jan;6(1)
Life science alliance 2023 Jan;6(1)
Gomphrena globosa L. extract alleviates carbon tetrachoride-induced liver injury in mice by activating antioxidant signaling pathways and promoting autophagy.
Wei Y, Tan W, Qin H, Jin M, Yu H, Cheng J, Feng H
Molecular biology reports 2023 Jan;50(1):97-106
Molecular biology reports 2023 Jan;50(1):97-106
Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.
Yang Z, Yan C, Ma J, Peng P, Ren X, Cai S, Shen X, Wu Y, Zhang S, Wang X, Qiu S, Zhou J, Fan J, Huang H, Gao Q
Nature metabolism 2023 Jan;5(1):61-79
Nature metabolism 2023 Jan;5(1):61-79
LncRNA LINC00534 regulates cell proliferation and migration via the miR-494-3p/PTEN axis in HTR-8/SVneo cells.
Song X, Zhang X, Xia Q, Li C, Zhang Y, Huang Y, Meng L, Wang C, Li J, Long W
Journal of clinical laboratory analysis 2023 Jan;37(1):e24802
Journal of clinical laboratory analysis 2023 Jan;37(1):e24802
VASN promotes colorectal cancer progression by activating the YAP/TAZ and AKT signaling pathways via YAP.
Liang W, Zuo J, Liu M, Su Y, Guo B, Hou J, Xing Q, Peng Y, Fang L, Cao Y, Shan J, Sun R, Zhao J, Wang J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Jan;37(1):e22688
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Jan;37(1):e22688
6-Methoxydihydrosanguinarine induces apoptosis and autophagy in breast cancer MCF-7 cells by accumulating ROS to suppress the PI3K/AKT/mTOR signaling pathway.
Zhang L, Zhang X, Che D, Zeng L, Zhang Y, Nan K, Zhang X, Zhang H, Guo Z
Phytotherapy research : PTR 2023 Jan;37(1):124-139
Phytotherapy research : PTR 2023 Jan;37(1):124-139
Neuroprotective effect of meglumine cyclic adenylate against ischemia/reperfusion injury via STAT3-Ser727 phosphorylation.
Niu XQ, Li DD, Bao YJ, Yang Q, Liu YK, Lu F, Yan JZ, Yin XH, Li C
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2023 Jan;32(1):106892
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2023 Jan;32(1):106892
N(6)-Methyladenosine-modified lncRNA LINREP promotes Glioblastoma progression by recruiting the PTBP1/HuR complex.
Ji X, Liu Z, Gao J, Bing X, He D, Liu W, Wang Y, Wei Y, Yin X, Zhang F, Han M, Lu X, Wang Z, Liu Q, Xin T
Cell death and differentiation 2023 Jan;30(1):54-68
Cell death and differentiation 2023 Jan;30(1):54-68
Bud31-mediated alternative splicing is required for spermatogonial stem cell self-renewal and differentiation.
Qin J, Huang T, Wang Z, Zhang X, Wang J, Dang Q, Cui D, Wang X, Zhai Y, Zhao L, Lu G, Shao C, Li S, Liu H, Liu Z
Cell death and differentiation 2023 Jan;30(1):184-194
Cell death and differentiation 2023 Jan;30(1):184-194
FAAH served a key membrane-anchoring and stabilizing role for NLRP3 protein independently of the endocannabinoid system.
Zhu Y, Zhang H, Mao H, Zhong S, Huang Y, Chen S, Yan K, Zhao Z, Hao X, Zhang Y, Yao H, Huang X, Wang M, Zhang W, Li J, Meng G, Qin X, Ye Z, Shen J, Song Y, Xu Y, Yang Z, Wang L, Zhang Y, Wen L
Cell death and differentiation 2023 Jan;30(1):168-183
Cell death and differentiation 2023 Jan;30(1):168-183
Quantitative reactive cysteinome profiling reveals a functional link between ferroptosis and proteasome-mediated degradation.
Wang Y, Wang C
Cell death and differentiation 2023 Jan;30(1):125-136
Cell death and differentiation 2023 Jan;30(1):125-136
Remodeling of imbalanced extracellular matrix homeostasis for reversal of pancreatic fibrosis.
Qi L, Han H, Han MM, Sun Y, Xing L, Jiang HL, Pandol SJ, Li L
Biomaterials 2023 Jan;292:121945
Biomaterials 2023 Jan;292:121945
Dexmedetomidine attenuates airway inflammation and oxidative stress in asthma via the Nrf2 signaling pathway.
Xiao S, Zhou Y, Gao H, Yang D
Molecular medicine reports 2023 Jan;27(1)
Molecular medicine reports 2023 Jan;27(1)
Metabolomic analysis and pharmacological validation of the cerebral protective effect of 3,4‑dihydroxybenzaldehyde on cerebral ischemia‑reperfusion injury.
Luo Y, Chen P, Yang L, Duan X
Molecular medicine reports 2023 Jan;27(1)
Molecular medicine reports 2023 Jan;27(1)
Chloride intracellular channel 1 promotes esophageal squamous cell carcinoma proliferation via mTOR signalling.
Geng H, Feng C, Sun Z, Fan X, Xie Y, Gu J, Fan L, Liu G, Li C, Thorne RF, Zhang XD, Li X, Liu X
Translational oncology 2023 Jan;27:101560
Translational oncology 2023 Jan;27:101560
FXR1 promotes proliferation, invasion and migration of hepatocellular carcinoma in vitro and in vivo.
Zhao K, Gao J, Shi J, Shi C, Pang C, Li J, Guo W, Zhang S
Oncology letters 2023 Jan;25(1):22
Oncology letters 2023 Jan;25(1):22
RBM24 inhibits the translation of SARS-CoV-2 polyproteins by targeting the 5'-untranslated region.
Yao Y, Sun H, Chen Y, Tian L, Huang D, Liu C, Zhou Y, Wang Y, Wen Z, Yang B, Chen X, Pei R
Antiviral research 2023 Jan;209:105478
Antiviral research 2023 Jan;209:105478
Upregulation of PIK3IP1 monitors the anti-cancer activity of PI3Kα inhibitors in gastric cancer cells.
Ma XB, Wang Y, Jia YJ, Liu YJ, Tian YQ, Liu Y, Hou GQ, Xu YC, Liu HM
Biochemical pharmacology 2023 Jan;207:115380
Biochemical pharmacology 2023 Jan;207:115380
Southern rice black-streaked dwarf virus induces incomplete autophagy for persistence in gut epithelial cells of its vector insect.
Zhang L, Liu W, Wu N, Wang H, Zhang Z, Liu Y, Wang X
PLoS pathogens 2023 Jan;19(1):e1011134
PLoS pathogens 2023 Jan;19(1):e1011134
c-kit(+)VEGFR-2(+) Mesenchymal Stem Cells Differentiate into Cardiovascular Cells and Repair Infarcted Myocardium after Transplantation.
Zhou P, Yu SN, Zhang HF, Wang YL, Tao P, Tan YZ, Wang HJ
Stem cell reviews and reports 2023 Jan;19(1):230-247
Stem cell reviews and reports 2023 Jan;19(1):230-247
Exosomal microRNA-4535 of Melanoma Stem Cells Promotes Metastasis by Inhibiting Autophagy Pathway.
Liu D, Li X, Zeng B, Zhao Q, Chen H, Zhang Y, Chen Y, Wang J, Xing HR
Stem cell reviews and reports 2023 Jan;19(1):155-169
Stem cell reviews and reports 2023 Jan;19(1):155-169
Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine.
Wang SM, Wu HE, Yasui Y, Geva M, Hayden M, Maurice T, Cozzolino M, Su TP
Autophagy 2023 Jan;19(1):126-151
Autophagy 2023 Jan;19(1):126-151
T-cell immunoglobulin- and mucin-domain-containing molecule-4 maintains adipose tissue homeostasis by orchestrating M2 macrophage polarization via nuclear factor kappa B pathway.
Ding L, Liang Y, Wang Y, Tong Z, Liu W, Tan S, Zhang J, Wang Y, Wu Z, Liang X, Ma C, Gao L
Immunology 2023 Jan;168(1):49-62
Immunology 2023 Jan;168(1):49-62
Exosomal miR-543 derived from umbilical cord mesenchymal stem cells ameliorates endometrial fibrosis in intrauterine adhesion via downregulating N-cadherin.
Yuan D, Guo T, Qian H, Jin C, Ge H, Zhao Y, Zhu D, Lin M, Wang H, Yu H
Placenta 2023 Jan;131:75-81
Placenta 2023 Jan;131:75-81
Flavonoids dimers from the fruits of Psoralea corylifolia and their cytotoxicity against MCF-7 cells.
Xu QX, Wang ZJ, He ZC, Xu J, Xu W, Yang XW
Bioorganic chemistry 2023 Jan;130:106262
Bioorganic chemistry 2023 Jan;130:106262
Downregulation of CBX7 induced by EZH2 upregulates FGFR3 expression to reduce sensitivity to cisplatin in bladder cancer.
Ren J, Yu H, Li W, Jin X, Yan B
British journal of cancer 2023 Jan;128(2):232-244
British journal of cancer 2023 Jan;128(2):232-244
Amyloid β oligomers disrupt piriform cortical output via a serotonergic pathway.
Wang X, Hu M, Xie Q, Geng C, Jin C, Ren W, Fan J, Ma T, Hu B
Neurobiology of aging 2023 Jan;121:64-77
Neurobiology of aging 2023 Jan;121:64-77
Banoxantrone Coordinated Metal-Organic Framework for Photoacoustic Imaging-Guided High Intensity Focused Ultrasound Therapy.
Sun T, Li J, Zeng C, Luo C, Luo X, Li H
Advanced healthcare materials 2023 Jan;12(2):e2202348
Advanced healthcare materials 2023 Jan;12(2):e2202348
Methotrexate and Triptolide regulate Notch signaling pathway by targeting the Nedd4-Numb axis.
Wu Q, Chen X, Qiao C, Cao X, Du Q, Yuan Y, Zuo Y, Miao Y, Zheng Z, Zhang T, Zang L, Yang X, Shi W, Xie Z, Xu Y, Wu D, Wen C, Zheng H
International immunopharmacology 2023 Jan;114:109595
International immunopharmacology 2023 Jan;114:109595
IL-33/ST2 axis promotes remodeling of the extracellular matrix and drives protective microglial responses in the mouse model of perioperative neurocognitive disorders.
Li S, Liu H, Qian Y, Jiang L, Liu S, Liu Y, Liu C, Gu X
International immunopharmacology 2023 Jan;114:109479
International immunopharmacology 2023 Jan;114:109479
Identification and characterization of novel carboxyl ester lipase gene variants in patients with different subtypes of diabetes.
Wu H, Shu M, Liu C, Zhao W, Li Q, Song Y, Zhang T, Chen X, Shi Y, Shi P, Fang L, Wang R, Xu C
BMJ open diabetes research & care 2023 Jan;11(1)
BMJ open diabetes research & care 2023 Jan;11(1)
Alantolactone induces concurrent apoptosis and GSDME-dependent pyroptosis of anaplastic thyroid cancer through ROS mitochondria-dependent caspase pathway.
Hu Y, Wen Q, Cai Y, Liu Y, Ma W, Li Q, Song F, Guo Y, Zhu L, Ge J, Zeng Q, Wang J, Yin C, Zheng G, Ge M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;108:154528
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;108:154528
Phosphoglycerate mutase 5 initiates inflammation in acute kidney injury by triggering mitochondrial DNA release by dephosphorylating the pro-apoptotic protein Bax.
Li J, Sun X, Yang N, Ni J, Xie H, Guo H, Wang X, Zhou L, Liu J, Chen S, Wang X, Zhang Y, Yu C, Zhang W, Lu L
Kidney international 2023 Jan;103(1):115-133
Kidney international 2023 Jan;103(1):115-133
Sclareol ameliorates liver injury by inhibiting nuclear factor-kappa B/NOD-like receptor protein 3-mediated inflammation and lipid metabolism disorder in diabetic mice.
Tang L, Mei X, Ye M, Liu Y, Huang Y, Yu J, Zhang L, Zhuge S, Jiang G, Zhu J
International journal of immunopathology and pharmacology 2023 Jan-Dec;37:3946320231223644
International journal of immunopathology and pharmacology 2023 Jan-Dec;37:3946320231223644
Boswellic acid coated zinc nanoparticles attenuate NF-κB-mediated inflammation in DSS-induced ulcerative colitis in rats.
Abou Zaid ES, Mansour SZ, El-Sonbaty SM, Moawed FS, Kandil EI, Haroun RA
International journal of immunopathology and pharmacology 2023 Jan-Dec;37:3946320221150720
International journal of immunopathology and pharmacology 2023 Jan-Dec;37:3946320221150720
CD27-Expressing Xenoantigen-Expanded Human Regulatory T Cells Are Efficient in Suppressing Xenogeneic Immune Response.
Cao L, Ma X, Zhang J, Yang M, He Z, Yang C, Li S, Rong P, Wang W
Cell transplantation 2023 Jan-Dec;32:9636897221149444
Cell transplantation 2023 Jan-Dec;32:9636897221149444
BDNF-TrkB signaling pathway-mediated microglial activation induces neuronal KCC2 downregulation contributing to dynamic allodynia following spared nerve injury.
Hu Z, Yu X, Chen P, Jin K, Zhou J, Wang G, Yu J, Wu T, Wang Y, Lin F, Zhang T, Wang Y, Zhao X
Molecular pain 2023 Jan-Dec;19:17448069231185439
Molecular pain 2023 Jan-Dec;19:17448069231185439
Study on the treatment of postmenopausal osteoporosis with quercetin in Liuwei Dihuang Pill based on network pharmacology.
Zhu F, Li W, Wang L, Dai B, Liu Z, Wu H, Deng T
Journal of orthopaedic surgery and research 2023 Jan 9;18(1):21
Journal of orthopaedic surgery and research 2023 Jan 9;18(1):21
iTRAQ-based Proteomic Analysis Unveils ACSL4 as a Novel Potential Regulator of Human Endometrial Receptivity.
Hu S, Sun Z, Li B, Zhao H, Wang Y, Yao G, Li X, Bian X, Li TC, Vankelecom H, Sun Y
Endocrinology 2023 Jan 9;164(3)
Endocrinology 2023 Jan 9;164(3)
Virulence factors and mechanisms of paediatric pneumonia caused by Enterococcus faecalis.
Tian Z, Khan AI, Rehman AU, Deng T, Ma C, Wang L
Gut pathogens 2023 Jan 9;15(1):2
Gut pathogens 2023 Jan 9;15(1):2
The Mechanosensitive Ion Channel PIEZO1 in Intestinal Epithelial Cells Mediates Inflammation through the NOD-Like Receptor 3 Pathway in Crohn's Disease.
Liu Q, Wang D, Yang X, Ma F, Han W, Hu J, Mei Q
Inflammatory bowel diseases 2023 Jan 5;29(1):103-115
Inflammatory bowel diseases 2023 Jan 5;29(1):103-115
A Mulberry Diels-Alder-Type Adduct, Kuwanon M, Triggers Apoptosis and Paraptosis of Lung Cancer Cells through Inducing Endoplasmic Reticulum Stress.
Ma M, Luan X, Zheng H, Wang X, Wang S, Shen T, Ren D
International journal of molecular sciences 2023 Jan 5;24(2)
International journal of molecular sciences 2023 Jan 5;24(2)
PRPF19 Limits Porcine Epidemic Diarrhea Virus Replication through Targeting and Degrading Viral Capsid Protein.
Zhai X, Kong N, Wang C, Qin W, Dong S, Zhai H, Yang X, Ye C, Ye M, Li G, Tong W, Liu C, Zheng H, Yu H, Zhang W, Yang X, Tong G, Shan T
Journal of virology 2023 Jan 31;97(1):e0161422
Journal of virology 2023 Jan 31;97(1):e0161422
SLC7A14 imports GABA to lysosomes and impairs hepatic insulin sensitivity via inhibiting mTORC2.
Jiang X, Liu K, Jiang H, Yin H, Wang ED, Cheng H, Yuan F, Xiao F, Wang F, Lu W, Peng B, Shu Y, Li X, Chen S, Guo F
Cell reports 2023 Jan 31;42(1):111984
Cell reports 2023 Jan 31;42(1):111984
A role of cytoplasmic p53 in the regulation of metabolism shown by bat-mimicking p53 NLS mutant mice.
Sanford JD, Jin A, Grois GA, Zhang Y
Cell reports 2023 Jan 31;42(1):111920
Cell reports 2023 Jan 31;42(1):111920
The deubiquitinase OTUD1 noncanonically suppresses Akt activation through its N-terminal intrinsically disordered region.
Fan G, Wang F, Chen Y, Zheng Q, Xiong J, Lv Q, Wu K, Xiong J, Wei L, Li D, Zhang J, Zhang W, Li F
Cell reports 2023 Jan 31;42(1):111916
Cell reports 2023 Jan 31;42(1):111916
Disruption of the Intestinal Mucosal Barrier Induced by High Fructose and Restraint Stress Is Regulated by the Intestinal Microbiota and Microbiota Metabolites.
Yu J, Liu T, Guo Q, Wang Z, Chen Y, Dong Y
Microbiology spectrum 2023 Jan 31;11(2):e0469822
Microbiology spectrum 2023 Jan 31;11(2):e0469822
Jinhua Qinggan granules attenuates acute lung injury by promotion of neutrophil apoptosis and inhibition of TLR4/MyD88/NF-κB pathway.
Zhu Y, Han Q, Wang L, Wang B, Chen J, Cai B, Wu C, Zhu X, Liu F, Han D, Dong H, Jia Y, Liu Y
Journal of ethnopharmacology 2023 Jan 30;301:115763
Journal of ethnopharmacology 2023 Jan 30;301:115763
Alteration in branching morphogenesis via YAP/TAZ in fibroblasts of fetal lungs in an LPS-induced inflammation model.
Ko HS, Laiman V, Tsao PN, Chen CM, Chuang HC
Molecular medicine (Cambridge, Mass.) 2023 Jan 30;29(1):16
Molecular medicine (Cambridge, Mass.) 2023 Jan 30;29(1):16
FTO-dependent m(6)A modification of Plpp3 in circSCMH1-regulated vascular repair and functional recovery following stroke.
Li B, Xi W, Bai Y, Liu X, Zhang Y, Li L, Bian L, Liu C, Tang Y, Shen L, Yang L, Gu X, Xie J, Zhou Z, Wang Y, Yu X, Wang J, Chao J, Han B, Yao H
Nature communications 2023 Jan 30;14(1):489
Nature communications 2023 Jan 30;14(1):489
LncRNA WDR11-AS1 Promotes Extracellular Matrix Synthesis in Osteoarthritis by Directly Interacting with RNA-Binding Protein PABPC1 to Stabilize SOX9 Expression.
Huang H, Yan J, Lan X, Guo Y, Sun M, Zhao Y, Zhang F, Sun J, Lu S
International journal of molecular sciences 2023 Jan 3;24(1)
International journal of molecular sciences 2023 Jan 3;24(1)
Ketogenic Diet Combined with Moderate Aerobic Exercise Training Ameliorates White Adipose Tissue Mass, Serum Biomarkers, and Hepatic Lipid Metabolism in High-Fat Diet-Induced Obese Mice.
Yan J, Ren C, Dong Y, Wali JA, Song H, Zhang Y, Zhang H, Kou G, Raubenheimer D, Cui Z
Nutrients 2023 Jan 3;15(1)
Nutrients 2023 Jan 3;15(1)
Vacuole Membrane Protein 1 (VMP1) Restricts NLRP3 Inflammasome Activation by Modulating SERCA Activity and Autophagy.
Zack SR, Nikolaienko R, Cook B, Melki R, Zima AV, Campbell EM
Research square 2023 Jan 27;
Research square 2023 Jan 27;
Identification of the Acid-Sensitive Site Critical for Chloral Hydrate (CH) Activation of the Proton-Activated Chloride Channel.
Xu XY, Zhang FF, Gan J, Zhang MY, Shen ZS, Guo Q, Teng Y, Ji JW, Cao JL, Tang QY, Zhang Z
The Journal of neuroscience : the official journal of the Society for Neuroscience 2023 Jan 25;43(4):526-539
The Journal of neuroscience : the official journal of the Society for Neuroscience 2023 Jan 25;43(4):526-539
Activation of NLRP3 inflammasome in lung epithelial cells triggers radiation-induced lung injury.
Rao X, Zhou D, Deng H, Chen Y, Wang J, Zhou X, Jie X, Xu Y, Wu Z, Wang G, Dong X, Zhang S, Meng R, Wu C, Xing S, Fan K, Wu G, Zhou R
Respiratory research 2023 Jan 24;24(1):25
Respiratory research 2023 Jan 24;24(1):25
Membrane-dependent actin polymerization mediated by the Legionella pneumophila effector protein MavH.
Zhang Q, Wan M, Mao Y
bioRxiv : the preprint server for biology 2023 Jan 24;
bioRxiv : the preprint server for biology 2023 Jan 24;
LIPUS accelerates bone regeneration via HDAC6-mediated ciliogenesis.
Xiao H, Yan A, Li M, Wang L, Xiang J
Biochemical and biophysical research communications 2023 Jan 22;641:34-41
Biochemical and biophysical research communications 2023 Jan 22;641:34-41
TRIM15 forms a regulatory loop with the AKT/FOXO1 axis and LASP1 to modulate the sensitivity of HCC cells to TKIs.
Yang C, Jin X, Liu X, Wu G, Yang W, Pang B, Jiang J, Liao D, Zhang Y
Cell death & disease 2023 Jan 20;14(1):47
Cell death & disease 2023 Jan 20;14(1):47
PHB2 promotes colorectal cancer cell proliferation and tumorigenesis through NDUFS1-mediated oxidative phosphorylation.
Ren L, Meng L, Gao J, Lu M, Guo C, Li Y, Rong Z, Ye Y
Cell death & disease 2023 Jan 20;14(1):44
Cell death & disease 2023 Jan 20;14(1):44
Photobiomodulation promotes spinal cord injury repair by inhibiting macrophage polarization through lncRNA TUG1-miR-1192/TLR3 axis.
Ju C, Ma Y, Zuo X, Wang X, Song Z, Zhang Z, Zhu Z, Li X, Liang Z, Ding T, Hu X, Wang Z
Cellular & molecular biology letters 2023 Jan 19;28(1):5
Cellular & molecular biology letters 2023 Jan 19;28(1):5
The role of atypical MAP kinase 4 in the host interaction with Cryptosporidium parvum.
Watanabe N, Bando H, Murakoshi F, Sakurai R, Kabir MHB, Fukuda Y, Kato K
Scientific reports 2023 Jan 19;13(1):1096
Scientific reports 2023 Jan 19;13(1):1096
Long noncoding RNA uc007nnj.1 mediates neuronal death induced by retinal ischemia/reperfusion in mice via the miR-155-5p/Tle4 axis.
Feng Y, Lu J, Peng X, Ge Y, Zhang R, Li H
Molecular medicine (Cambridge, Mass.) 2023 Jan 18;29(1):9
Molecular medicine (Cambridge, Mass.) 2023 Jan 18;29(1):9
Structural basis of bacterial effector protein azurin targeting tumor suppressor p53 and inhibiting its ubiquitination.
Hu J, Jiang W, Zuo J, Shi D, Chen X, Yang X, Zhang W, Ma L, Liu Z, Xing Q
Communications biology 2023 Jan 17;6(1):59
Communications biology 2023 Jan 17;6(1):59
The natural flavone acacetin protects against high-fat diet-induced lipid accumulation in the liver via the endoplasmic reticulum stress/ferroptosis pathway.
Jiang Z, Sun H, Miao J, Sheng Q, Xu J, Gao Z, Zhang X, Song Y, Chen K
Biochemical and biophysical research communications 2023 Jan 15;640:183-191
Biochemical and biophysical research communications 2023 Jan 15;640:183-191
Knockdown of PKMYT1 is associated with autophagy inhibition and apoptosis induction and suppresses tumor progression in hepatocellular carcinoma.
Wu F, Tu C, Zhang K, Che H, Lin Q, Li Z, Zhou Q, Tang B, Yang Y, Chen M, Shao C
Biochemical and biophysical research communications 2023 Jan 15;640:173-182
Biochemical and biophysical research communications 2023 Jan 15;640:173-182
Novel insights into the mediating roles of cluster of differentiation 36 in transmembrane transport and tissue partition of per- and polyfluoroalkyl substances in mice.
Jia Y, Zhu Y, Wang R, Ye Q, Xu D, Zhang W, Zhang Y, Shan G, Zhu L
Journal of hazardous materials 2023 Jan 15;442:130129
Journal of hazardous materials 2023 Jan 15;442:130129
Inhibition of cGAS ameliorates acute lung injury triggered by zinc oxide nanoparticles.
Jiang Z, Jiang Y, Fan J, Zhang J, Xu G, Fan Y, Zhang L, Qin X, Jiang X, Mao L, Liu G, Chen C, Zou Z
Toxicology letters 2023 Jan 15;373:62-75
Toxicology letters 2023 Jan 15;373:62-75
BAP31 regulates the expression of ICAM-1/VCAM-1 via MyD88/NF-κB pathway in acute lung injury mice model.
Li G, Jiang X, Liang X, Hou Y, Zang J, Zhu B, Jia C, Niu K, Liu X, Xu X, Jiang R, Wang B
Life sciences 2023 Jan 15;313:121310
Life sciences 2023 Jan 15;313:121310
The U2AF65/circNCAPG/RREB1 feedback loop promotes malignant phenotypes of glioma stem cells through activating the TGF-β pathway.
Li H, Jiang Y, Hu J, Xu J, Chen L, Zhang G, Zhao J, Zong S, Guo Z, Li X, Zhao X, Jing Z
Cell death & disease 2023 Jan 13;14(1):23
Cell death & disease 2023 Jan 13;14(1):23
Flavivirus prM interacts with MDA5 and MAVS to inhibit RLR antiviral signaling.
Sui L, Zhao Y, Wang W, Chi H, Tian T, Wu P, Zhang J, Zhao Y, Wei ZK, Hou Z, Zhou G, Wang G, Wang Z, Liu Q
Cell & bioscience 2023 Jan 13;13(1):9
Cell & bioscience 2023 Jan 13;13(1):9
Betulinaldehyde exhibits effective anti-tumor effects in A549 cells by regulating intracellular autophagy.
Huang PH, Duan XB, Tang ZZ, Zou ZX, Song WM, Gao G, Li D, Nie FQ, Yan X, Fu YX, Guo R, Xu YY
Scientific reports 2023 Jan 13;13(1):743
Scientific reports 2023 Jan 13;13(1):743
Discovery of rafoxanide as a novel agent for the treatment of non-small cell lung cancer.
Hu A, Liu J, Wang Y, Zhang M, Guo Y, Qin Y, Liu T, Men Y, Chen Q, Liu T
Scientific reports 2023 Jan 13;13(1):693
Scientific reports 2023 Jan 13;13(1):693
Crizotinib Nanomicelles Synergize with Chemotherapy through Inducing Proteasomal Degradation of Mutp53 Proteins.
Yi T, Qian J, Ye Y, Zhang H, Jin X, Wang M, Yang Z, Zhang W, Wen L, Zhang Y
ACS applied materials & interfaces 2023 Jan 11;15(1):511-523
ACS applied materials & interfaces 2023 Jan 11;15(1):511-523
PFC@O(2) Targets HIF-1α to Reverse the Immunosuppressive TME in OSCC.
Lan Z, Zou KL, Cui H, Chen H, Zhao YY, Yu GT
Journal of clinical medicine 2023 Jan 10;12(2)
Journal of clinical medicine 2023 Jan 10;12(2)
Dioscin reduced chemoresistance for colon cancer and analysis of sensitizing targets.
Li R, Qin J, Wang Z, Lv F, Guo J, Zhu H, Huang Y
Biochemical and biophysical research communications 2023 Jan 1;638:94-102
Biochemical and biophysical research communications 2023 Jan 1;638:94-102
Ablation of AQP5 gene in mice leads to olfactory dysfunction caused by hyposecretion of Bowman's gland.
Zhao X, Liu G, Yu X, Yang X, Gao W, Zhao Z, Ma T, Ma J
Chemical senses 2023 Jan 1;48
Chemical senses 2023 Jan 1;48
Toxicity of polystyrene nanoparticles for mouse ovary and cultured human granulosa cells.
Huang J, Zou L, Bao M, Feng Q, Xia W, Zhu C
Ecotoxicology and environmental safety 2023 Jan 1;249:114371
Ecotoxicology and environmental safety 2023 Jan 1;249:114371
A Prevascularized Sinus Tract on the Liver Surface for Islet Transplantation.
Li F, Lv Y, Li X, Yang Z, Guo T, Zhang J
Transplantation 2023 Jan 1;107(1):117-128
Transplantation 2023 Jan 1;107(1):117-128
M2 macrophages with inflammation tropism facilitate cementoblast mineralization.
Huang X, Wang X, Ma L, Wang H, Peng Y, Liu H, Xiao J, Cao Z
Journal of periodontology 2023 Feb;94(2):290-300
Journal of periodontology 2023 Feb;94(2):290-300
Luteolin improves vasoconstriction function and survival of septic mice via AMPK/NF-κB pathway.
Liu B, Su H
Heliyon 2023 Feb;9(2):e13330
Heliyon 2023 Feb;9(2):e13330
Triptonide inhibits growth and metastasis in HCC by suppressing EGFR/PI3K/AKT signaling.
Zhang H, Mao Y, Zou X, Niu J, Jiang J, Chen X, Zhu M, Yang X, Dong T
Neoplasma 2023 Feb;70(1):94-102
Neoplasma 2023 Feb;70(1):94-102
CRISPR-Cas9-Mediated NPC1 Gene Deletion Enhances HEK 293 T Cell Adhesion by Regulating E-Cadherin.
Jia Z, Yang M, Zhao Y, Li X, Yang C, Qiao L, Li H, Du J, Lin J, Guan L
Molecular biotechnology 2023 Feb;65(2):252-262
Molecular biotechnology 2023 Feb;65(2):252-262
Moderate-Intensity Treadmill Exercise Promotes mTOR-Dependent Motor Cortical Neurotrophic Factor Expression and Functional Recovery in a Murine Model of Crush Spinal Cord Injury (SCI).
Zhan Z, Pan L, Zhu Y, Wang Y, Zhao Q, Liu Y, Li S, Wang H, Yang C, Yu L, Yin Y, Tan B
Molecular neurobiology 2023 Feb;60(2):960-978
Molecular neurobiology 2023 Feb;60(2):960-978
Disrupted in renal carcinoma 2 (DIRC2/SLC49A4) is an H(+)-driven lysosomal pyridoxine exporter.
Akino S, Yasujima T, Yamashiro T, Yuasa H
Life science alliance 2023 Feb;6(2)
Life science alliance 2023 Feb;6(2)
The role of Sirt3-induced autophagy in renal structural damage caused by periodontitis in rats.
Ding X, Hou Y, Liu X, Li X, Liu X, Deng Y, Cao N, Yu W
Journal of periodontal research 2023 Feb;58(1):97-108
Journal of periodontal research 2023 Feb;58(1):97-108
Cul5 mediates taurine-stimulated mTOR mRNA expression and proliferation of mouse mammary epithelial cells.
Xu M, Zhou Y, Fan S, Zhang M, Gao X
Amino acids 2023 Feb;55(2):243-252
Amino acids 2023 Feb;55(2):243-252
Fc receptor-like 1 (FCRL1) is a novel biomarker for prognosis and a possible therapeutic target in diffuse large B-cell lymphoma.
Yousefi Z, Sharifzadeh S, Zare F, Eskandari N
Molecular biology reports 2023 Feb;50(2):1133-1145
Molecular biology reports 2023 Feb;50(2):1133-1145
Extracellular acidosis restricts one-carbon metabolism and preserves T cell stemness.
Cheng H, Qiu Y, Xu Y, Chen L, Ma K, Tao M, Frankiw L, Yin H, Xie E, Pan X, Du J, Wang Z, Zhu W, Chen L, Zhang L, Li G
Nature metabolism 2023 Feb;5(2):314-330
Nature metabolism 2023 Feb;5(2):314-330
POU Domain Class 2 Transcription Factor 2 Inhibits Ferroptosis in Cerebral Ischemia Reperfusion Injury by Activating Sestrin2.
Yang J, Guo Q, Wang L, Yu S
Neurochemical research 2023 Feb;48(2):658-670
Neurochemical research 2023 Feb;48(2):658-670
MiR-29c Inhibits TNF-α-Induced ROS Production and Apoptosis in Mouse Hippocampal HT22 Cell Line.
Li B, Lu Y, Wang R, Xu T, Lei X, Jin H, Gao X, Xie Y, Liu X, Zeng J
Neurochemical research 2023 Feb;48(2):519-536
Neurochemical research 2023 Feb;48(2):519-536
Anti-inflammatory effects of extracellular vesicles from Morchella on LPS-stimulated RAW264.7 cells via the ROS-mediated p38 MAPK signaling pathway.
Chen Q, Che C, Yang S, Ding P, Si M, Yang G
Molecular and cellular biochemistry 2023 Feb;478(2):317-327
Molecular and cellular biochemistry 2023 Feb;478(2):317-327
PKMYT1 inhibits lung adenocarcinoma progression by abrogating AKT1 activity.
Wang S, Liu X, Zhou T, Li J, Lin Y, Zhou A, Huang J, Zhao J, Cai J, Cai X, Huang Y, Li X
Cellular oncology (Dordrecht, Netherlands) 2023 Feb;46(1):195-209
Cellular oncology (Dordrecht, Netherlands) 2023 Feb;46(1):195-209
Oligosaccharide Blocks PAR1 (Proteinase-Activated Receptor 1)-PAR4-Mediated Platelet Activation by Binding to Thrombin Exosite II and Impairs Thrombosis.
Li S, Wang W, Lin L, Yang L, Cai Y, Yang X, Zhang T, Xiao C, Yan H, Gao N, Zhao J
Arteriosclerosis, thrombosis, and vascular biology 2023 Feb;43(2):253-266
Arteriosclerosis, thrombosis, and vascular biology 2023 Feb;43(2):253-266
miR-34b-3p Inhibition of eIF4E Causes Post-stroke Depression in Adult Mice.
Ke X, Deng M, Wu Z, Yu H, Yu D, Li H, Lu Y, Shu K, Pei L
Neuroscience bulletin 2023 Feb;39(2):194-212
Neuroscience bulletin 2023 Feb;39(2):194-212
The cytotoxicity of zinc oxide nanoparticles to 3D brain organoids results from excessive intracellular zinc ions and defective autophagy.
Liu L, Wang J, Zhang J, Huang C, Yang Z, Cao Y
Cell biology and toxicology 2023 Feb;39(1):259-275
Cell biology and toxicology 2023 Feb;39(1):259-275
STAT3/Mitophagy Axis Coordinates Macrophage NLRP3 Inflammasome Activation and Inflammatory Bone Loss.
Zhu L, Wang Z, Sun X, Yu J, Li T, Zhao H, Ji Y, Peng B, Du M
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2023 Feb;38(2):335-353
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2023 Feb;38(2):335-353
Bone marrow mesenchymal stem cells repair hexavalent chromium-induced testicular injury by regulating autophagy and ferroptosis mediated by the AKT/mTOR pathway in rats.
Zhuge R, Li Z, He C, Ma W, Yan J, Xue Q, Wang R, Liu Y, Lu R, Du H, Yin F, Guo L
Environmental toxicology 2023 Feb;38(2):289-299
Environmental toxicology 2023 Feb;38(2):289-299
Ubiquitin-specific protease 24 promotes EV71 infection by restricting K63-linked polyubiquitination of TBK1.
Zang L, Gu J, Yang X, Yuan Y, Guo H, Zhou W, Ma J, Chen Y, Wu Y, Zheng H, Shi W
Virologica Sinica 2023 Feb;38(1):75-83
Virologica Sinica 2023 Feb;38(1):75-83
Paeoniflorin-6'-O-benzene sulfonate protected the intestinal epithelial barrier by restoring the inhibitory effect of GRK2 and β-arrestin 2 on ERK1/2-NF-κB.
Jiang M, Tang C, Yang M, Li Y, Wang W, Wang C, Wei W, Chen J
Phytotherapy research : PTR 2023 Feb;37(2):743-758
Phytotherapy research : PTR 2023 Feb;37(2):743-758
N(6)-methyladenosine-modified USP13 induces pro-survival autophagy and imatinib resistance via regulating the stabilization of autophagy-related protein 5 in gastrointestinal stromal tumors.
Gao Z, Li C, Sun H, Bian Y, Cui Z, Wang N, Wang Z, Yang Y, Liu Z, He Z, Li B, Li F, Li Z, Wang L, Zhang D, Yang L, Xu Z, Li X, Xu H
Cell death and differentiation 2023 Feb;30(2):544-559
Cell death and differentiation 2023 Feb;30(2):544-559
Forced activation of dystrophin transcription by CRISPR/dCas9 reduced arrhythmia susceptibility via restoring membrane Nav1.5 distribution.
Zhang R, Liu J, Xue G, Yang J, Li D, Tian T, Zhang X, Gao K, Pan Z
Gene therapy 2023 Feb;30(1-2):142-149
Gene therapy 2023 Feb;30(1-2):142-149
TIPE1 promotes liver regeneration by enhancing ROS-FoxO1 axis mediated autophagy.
Zhang X, Li S, Ren X, Xiang P, Zhang Y, Wang T, Qin Q, Sun F, Liu J, Gao L, Ma C, Yue X, Yang X, Han S, Liang X
The FEBS journal 2023 Feb;290(4):1117-1133
The FEBS journal 2023 Feb;290(4):1117-1133
Landscape of pathogenic mutations in premature ovarian insufficiency.
Ke H, Tang S, Guo T, Hou D, Jiao X, Li S, Luo W, Xu B, Zhao S, Li G, Zhang X, Xu S, Wang L, Wu Y, Wang J, Zhang F, Qin Y, Jin L, Chen ZJ
Nature medicine 2023 Feb;29(2):483-492
Nature medicine 2023 Feb;29(2):483-492
KIAA1199 promotes oxaliplatin resistance and epithelial mesenchymal transition of colorectal cancer via protein O-GlcNAcylation.
Hua Q, Lu Y, Wang D, Da J, Peng W, Sun G, Gu K, Wang H, Zhu Y
Translational oncology 2023 Feb;28:101617
Translational oncology 2023 Feb;28:101617
Pirfenidone suppressed triple-negative breast cancer metastasis by inhibiting the activity of the TGF-β/SMAD pathway.
Luo D, Zeng X, Zhang S, Li D, Cheng Z, Wang Y, Long J, Hu Z, Long S, Zhou J, Zhang S, Zeng Z
Journal of cellular and molecular medicine 2023 Feb;27(3):456-469
Journal of cellular and molecular medicine 2023 Feb;27(3):456-469
Role of SUMOylation of STAT1 in tubular epithelial‑mesenchymal transition induced by high glucose.
Gu C, Gao F, Zhang S, Kang L, Zhang W, Feng X, Liu J, Tian Y, Wei Q, Du Y, Xing Y, Liu Q, Liu S
Molecular medicine reports 2023 Feb;27(2)
Molecular medicine reports 2023 Feb;27(2)
Mechanism of autophagy mediated by IGF-1 signaling pathway in the neurotoxicity of lead in pubertal rats.
Zhang B, Li H, Wang Y, Li Y, Zhou Z, Hou X, Zhang X, Liu T
Ecotoxicology and environmental safety 2023 Feb;251:114557
Ecotoxicology and environmental safety 2023 Feb;251:114557
YTHDF2 orchestrates tumor-associated macrophage reprogramming and controls antitumor immunity through CD8(+) T cells.
Ma S, Sun B, Duan S, Han J, Barr T, Zhang J, Bissonnette MB, Kortylewski M, He C, Chen J, Caligiuri MA, Yu J
Nature immunology 2023 Feb;24(2):255-266
Nature immunology 2023 Feb;24(2):255-266
Mitochondrial targeting half-sandwich iridium(III) and ruthenium(II) dppf complexes and in vitro anticancer assay.
Liu J, Wu Y, Yang G, Liu Z, Liu X
Journal of inorganic biochemistry 2023 Feb;239:112069
Journal of inorganic biochemistry 2023 Feb;239:112069
Inositol polyphosphates-regulated polyubiquitination of PHR1 by NLA E3 ligase during phosphate starvation response in Arabidopsis.
Park SH, Jeong JS, Huang CH, Park BS, Chua NH
The New phytologist 2023 Feb;237(4):1215-1228
The New phytologist 2023 Feb;237(4):1215-1228
Effects of substrate topography on the regulation of human fibroblasts and capsule formation via modulating macrophage polarization.
Chen C, Chen Y, Lan YJ, Tian MN, Zhang YM, Lei ZY, Fan DL
Colloids and surfaces. B, Biointerfaces 2023 Feb;222:113086
Colloids and surfaces. B, Biointerfaces 2023 Feb;222:113086
Barrier-penetrating liposome targeted delivery of basic fibroblast growth factor for spinal cord injury repair.
Wu F, Wang P, Wei X, Yang Y, Al Mamun A, Zhang X, Zhu Y, Mo T, Zhang H, Jiang C, Hu J, Xiao J
Materials today. Bio 2023 Feb;18:100546
Materials today. Bio 2023 Feb;18:100546
LncRNA NR2F1-AS1 was involved in azacitidine resistance of THP-1 cells by targeting IGF1 with miR-483-3p.
Hu C, Li S, Fu X, Zhao X, Peng J
Cytokine 2023 Feb;162:156105
Cytokine 2023 Feb;162:156105
A biomaterial-based therapy using a sodium hyaluronate/bioglass composite hydrogel for the treatment of oral submucous fibrosis.
Guo ZX, Zhang Z, Yan JF, Xu HQ, Wang SY, Ye T, Han XX, Wang WR, Wang Y, Gao JL, Niu LN, Chang J, Jiao K
Acta biomaterialia 2023 Feb;157:639-654
Acta biomaterialia 2023 Feb;157:639-654
Hyperbaric oxygen enhanced the chemotherapy of mitochondrial targeting molecule IR-780 in bladder cancer.
Shen C, Yue X, Dai L, Wang J, Li J, Fang Q, Zhi Y, Shi C, Li W
Journal of cancer research and clinical oncology 2023 Feb;149(2):683-699
Journal of cancer research and clinical oncology 2023 Feb;149(2):683-699
Costunolide covalently targets NACHT domain of NLRP3 to inhibit inflammasome activation and alleviate NLRP3-driven inflammatory diseases.
Xu H, Chen J, Chen P, Li W, Shao J, Hong S, Wang Y, Chen L, Luo W, Liang G
Acta pharmaceutica Sinica. B 2023 Feb;13(2):678-693
Acta pharmaceutica Sinica. B 2023 Feb;13(2):678-693
Identification of miR-30c-5p as a tumor suppressor by targeting the m(6) A reader HNRNPA2B1 in ovarian cancer.
Wu Q, Li G, Gong L, Cai J, Chen L, Xu X, Liu X, Zhao J, Zeng Y, Gao R, Yu L, Wang Z
Cancer medicine 2023 Feb;12(4):5055-5070
Cancer medicine 2023 Feb;12(4):5055-5070
Macrophage migration inhibitory factor (MIF) inhibitor iSO-1 promotes staphylococcal protein A-induced osteogenic differentiation by inhibiting NF-κB signaling pathway.
Shi X, Wu Y, Ni H, Li M, Qi B, Xu Y
International immunopharmacology 2023 Feb;115:109600
International immunopharmacology 2023 Feb;115:109600
Transcriptome analysis highlights the role of ferroptosis in palmitic acid-induced endothelial dysfunction.
Tan XH, Gu YY, Song WP, Nan TG, Song WD, Fang D, Yuan YM, Xin ZC, Li XS, Guan RL
Sexual medicine 2023 Feb;11(1):qfac008
Sexual medicine 2023 Feb;11(1):qfac008
Sestrin2 contributes to BRAF inhibitor resistance via reducing redox vulnerability of melanoma cells.
Guo S, Yue Q, Wang S, Wang H, Ye Z, Zhang W, Shi Q, Gao T, Li C, Zhu G
Journal of dermatological science 2023 Feb;109(2):52-60
Journal of dermatological science 2023 Feb;109(2):52-60
Manipulation of PD-L1 Endosomal Trafficking Promotes Anticancer Immunity.
Ye Z, Xiong Y, Peng W, Wei W, Huang L, Yue J, Zhang C, Lin G, Huang F, Zhang L, Zheng S, Yue J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Feb;10(6):e2206411
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Feb;10(6):e2206411
Low temperature exposure inhibits proliferation and induces apoptosis of bovine subcutaneous preadipocytes via p38 MAPK/JNK activation.
Li T, Bai H, Yang L, Hao W, Wei S, Yan P
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2023 Feb-Mar;264:110813
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2023 Feb-Mar;264:110813
The Prognostic Value and the Oncogenic and Immunological Roles of Vacuolar Protein Sorting Associated Protein 26 A in Pancreatic Adenocarcinoma.
Hou J, Wu H, Xu B, Shang J, Xu X, Li G, Zhang H, Zhang W, Deng Y, Hong X, Hu T, Zhang M, Zhan Y
International journal of molecular sciences 2023 Feb 9;24(4)
International journal of molecular sciences 2023 Feb 9;24(4)
Morphometric analysis of the size-adjusted linear dimensions of the skull landmarks revealed craniofacial dysmorphology in Mid1-cKO mice.
Liang Y, Song C, Li J, Li T, Zhang C, Zou Y
BMC genomics 2023 Feb 9;24(1):68
BMC genomics 2023 Feb 9;24(1):68
Protective Effect of 20(S)-Protopanaxadiol on D-Gal-Induced Cognitively Impaired Mice Based on Its Target Protein Brain-type Creatine Kinase.
Zhang H, Chen F, Xu S, Zhang W, Li R, Yao Q, Zhao Y, Zhu Z, Chen L
Journal of agricultural and food chemistry 2023 Feb 8;
Journal of agricultural and food chemistry 2023 Feb 8;
Ginsenoside Rg3 Ameliorates DSS-Induced Colitis by Inhibiting NLRP3 Inflammasome Activation and Regulating Microbial Homeostasis.
Liu D, Tian Q, Liu K, Ren F, Liu G, Zhou J, Yuan L, Fang Z, Zou B, Wang S
Journal of agricultural and food chemistry 2023 Feb 8;
Journal of agricultural and food chemistry 2023 Feb 8;
Viral Hemorrhagic Septicemia Virus Activates Integrated Stress Response Pathway and Induces Stress Granules to Regulate Virus Replication.
Ramnani B, Powell S, Shetty AG, Manivannan P, Hibbard BR, Leaman DW, Malathi K
Viruses 2023 Feb 7;15(2)
Viruses 2023 Feb 7;15(2)
Myristic acid as a checkpoint to regulate STING-dependent autophagy and interferon responses by promoting N-myristoylation.
Jia M, Wang Y, Wang J, Qin D, Wang M, Chai L, Fu Y, Zhao C, Gao C, Jia J, Zhao W
Nature communications 2023 Feb 7;14(1):660
Nature communications 2023 Feb 7;14(1):660
Methyltransferase-like 3 aggravates endoplasmic reticulum stress in preeclampsia by targeting TMBIM6 in YTHDF2-dependent manner.
Chen Y, Liu X, Li L, He X, Zheng F, Zhang Y, Gao H, Jin Z, Wu D, Wang Q, Tao H, Zhao Y, Liu W, Zou L
Molecular medicine (Cambridge, Mass.) 2023 Feb 6;29(1):19
Molecular medicine (Cambridge, Mass.) 2023 Feb 6;29(1):19
Chromatin remodeler BRM is a key mediator of leucine-stimulated mTOR gene transcription in mouse mammary epithelial cells.
Ke C, Zhao S, Wang L, Zhang M, Gao X
Biochemical and biophysical research communications 2023 Feb 5;643:88-95
Biochemical and biophysical research communications 2023 Feb 5;643:88-95
Ang-(1-7)/MasR axis promotes functional recovery after spinal cord injury by regulating microglia/macrophage polarization.
Gu G, Zhu B, Ren J, Song X, Fan B, Ding H, Shang J, Wu H, Li J, Wang H, Li J, Wei Z, Feng S
Cell & bioscience 2023 Feb 4;13(1):23
Cell & bioscience 2023 Feb 4;13(1):23
Ant-Neointimal Formation Effects of SLC6A6 in Preventing Vascular Smooth Muscle Cell Proliferation and Migration via Wnt/β-Catenin Signaling.
Rong Z, Li F, Zhang R, Niu S, Di X, Ni L, Liu C
International journal of molecular sciences 2023 Feb 3;24(3)
International journal of molecular sciences 2023 Feb 3;24(3)
Microglia PKM2 Mediates Neuroinflammation and Neuron Loss in Mice Epilepsy through the Astrocyte C3-Neuron C3R Signaling Pathway.
Li X, Zhou R, Peng H, Peng J, Li Q, Mei M
Brain sciences 2023 Feb 3;13(2)
Brain sciences 2023 Feb 3;13(2)
Cofilin promotes tau pathology in Alzheimer's disease.
Yan M, Tang L, Dai L, Lei C, Xiong M, Zhang X, He M, Tian Y, Xiong J, Ke W, Zhang Z, Zhang C, Deng X, Zhang Z
Cell reports 2023 Feb 28;42(2):112138
Cell reports 2023 Feb 28;42(2):112138
E2F1 inhibits cellular senescence and promotes oxaliplatin resistance in colorectal cancer.
Gao H, Zhou F, Li R, Yuan J, Ye L
Annals of translational medicine 2023 Feb 28;11(4):185
Annals of translational medicine 2023 Feb 28;11(4):185
Naringenin is a Potential Immunomodulator for Inhibiting Liver Fibrosis by Inhibiting the cGAS-STING Pathway.
Chen L, Xia S, Wang S, Zhou Y, Wang F, Li Z, Li Y, Kong D, Zhang Z, Shao J, Xu X, Zhang F, Zheng S
Journal of clinical and translational hepatology 2023 Feb 28;11(1):26-37
Journal of clinical and translational hepatology 2023 Feb 28;11(1):26-37
Lactobacillus johnsonii L531 Ameliorates Salmonella enterica Serovar Typhimurium Diarrhea by Modulating Iron Homeostasis and Oxidative Stress via the IRP2 Pathway.
Chen K, Wang J, Guo L, Wang J, Yang L, Hu T, Zhao Y, Wang X, Zhu Y
Nutrients 2023 Feb 23;15(5)
Nutrients 2023 Feb 23;15(5)
Peroxiredoxin-6 Released by Astrocytes Contributes to Neuroapoptosis During Ischemia.
Hou JY, Zhou XL, Wang XY, Liang J, Xue Q
Neuroscience 2023 Feb 21;512:59-69
Neuroscience 2023 Feb 21;512:59-69
Cyanidin-3-O-glucoside and protocatechuic acid alleviate heat stress-induced testicular damage.
Cai D, Li X, Xu Q, Li H, Liu R, Chen J, Jiang X, Sun J, Lai C, Bai W
Food & function 2023 Feb 21;14(4):2200-2211
Food & function 2023 Feb 21;14(4):2200-2211
Synergistic effects of L-theanine and epigallocatechin gallate in alleviating ovalbumin allergy by regulating intestinal immunity through inhibition of mast cell degranulation.
Xu W, Song X, Qu Q, Gong Z, Xiao W
Food & function 2023 Feb 21;14(4):2059-2073
Food & function 2023 Feb 21;14(4):2059-2073
TIM-4 orchestrates mitochondrial homeostasis to promote lung cancer progression via ANXA2/PI3K/AKT/OPA1 axis.
Wang Y, Wang Y, Liu W, Ding L, Zhang X, Wang B, Tong Z, Yue X, Li C, Xu L, Wu Z, Liang X, Ma C, Gao L
Cell death & disease 2023 Feb 20;14(2):141
Cell death & disease 2023 Feb 20;14(2):141
Enterococcus faecalis promotes the progression of colorectal cancer via its metabolite: biliverdin.
Zhang L, Liu J, Deng M, Chen X, Jiang L, Zhang J, Tao L, Yu W, Qiu Y
Journal of translational medicine 2023 Feb 2;21(1):72
Journal of translational medicine 2023 Feb 2;21(1):72
Optimization of Primary Human Bronchial Epithelial 3D Cell Culture with Donor-Matched Fibroblasts and Comparison of Two Different Culture Media.
Maurer J, Walles T, Wiese-Rischke C
International journal of molecular sciences 2023 Feb 18;24(4)
International journal of molecular sciences 2023 Feb 18;24(4)
Circular RNA METTL9 contributes to neuroinflammation following traumatic brain injury by complexing with astrocytic SND1.
Huang C, Sun L, Xiao C, You W, Sun L, Wang S, Zhang Z, Liu S
Journal of neuroinflammation 2023 Feb 17;20(1):39
Journal of neuroinflammation 2023 Feb 17;20(1):39
Nanodrug rescues liver fibrosis via synergistic therapy with H(2)O(2) depletion and Saikosaponin b1 sustained release.
Dong H, Han X, Hao M, Yang Q, Lyu Q, Tang D, Shen Z, Wang K, Kuang H, Cao G, Peng M, Shao M
Communications biology 2023 Feb 16;6(1):184
Communications biology 2023 Feb 16;6(1):184
RGS12 represses oral squamous cell carcinoma by driving M1 polarization of tumor-associated macrophages via controlling ciliary MYCBP2/KIF2A signaling.
Yuan G, Yang S, Yang S
International journal of oral science 2023 Feb 16;15(1):11
International journal of oral science 2023 Feb 16;15(1):11
Thiram-induced hyperglycemia causes tibial dyschondroplasia by triggering aberrant ECM remodeling via the gut-pancreas axis in broiler chickens.
Mo Q, Kulyar MF, Quan C, Ding Y, Zhang Y, Zhang L, Pan H, Li J
Journal of hazardous materials 2023 Feb 15;444(Pt A):130368
Journal of hazardous materials 2023 Feb 15;444(Pt A):130368
Disorders in the gut and liver are involved in depression contagion between isosexual post-stroke depression mice and the healthy cohabitors.
Wang H, Bin Wang, Pan MB, Jiang ST, Wang YC, Zhu Y, Zhang QC, Dong YF
Behavioural brain research 2023 Feb 15;439:114246
Behavioural brain research 2023 Feb 15;439:114246
Hexokinase 2-mediated glycolysis supports inflammatory responses to Porphyromonas gingivalis in gingival fibroblasts.
Su W, Li J, Jiang L, Lei L, Li H
BMC oral health 2023 Feb 15;23(1):103
BMC oral health 2023 Feb 15;23(1):103
CMTM3 protects the gastric epithelial cells from apoptosis and promotes IL-8 by stabilizing NEMO during Helicobacter pylori infection.
Zhang J, Ning J, Fu W, Shi Y, Zhang J, Ding S
Gut pathogens 2023 Feb 13;15(1):6
Gut pathogens 2023 Feb 13;15(1):6
Exosomal lncRNA HOTAIR induces PDL1(+) B cells to impede anti-tumor immunity in colorectal cancer.
Xie Z, Xia J, Jiao M, Zhao P, Wang Z, Lin S, Xing Y, Li Y, Lu Z, Zhong Z, Miao C, Zhou P, Qian J, Wang L, Zhang D, Gu J, Chu Y, Liu R
Biochemical and biophysical research communications 2023 Feb 12;644:112-121
Biochemical and biophysical research communications 2023 Feb 12;644:112-121
Qingre Huazhuo Jiangsuan Decoction promotes autophagy by inhibiting PI3K/AKT/mTOR signaling pathway to relieve acute gouty arthritis.
Liu P, Xu Y, Ye J, Tan J, Hou J, Wang Y, Li J, Cui W, Wang S, Zhao Q
Journal of ethnopharmacology 2023 Feb 10;302(Pt A):115875
Journal of ethnopharmacology 2023 Feb 10;302(Pt A):115875
Macrophage Migration Inhibitory Factor Promotes Expression of Matrix Metalloproteinases 1 and 3 in Spinal Cord Astrocytes following Gecko Tail Amputation.
Zhang H, Sun C, He B, Zhang X, Hao H, Hou Y, Li A, Wang Y, Wang Y
Journal of integrative neuroscience 2023 Feb 10;22(2):29
Journal of integrative neuroscience 2023 Feb 10;22(2):29
Melanin-like polydopamine nanoparticles mediating anti-inflammatory and rescuing synaptic loss for inflammatory depression therapy.
Zhu TT, Wang H, Gu HW, Ju LS, Wu XM, Pan WT, Zhao MM, Yang JJ, Liu PM
Journal of nanobiotechnology 2023 Feb 10;21(1):52
Journal of nanobiotechnology 2023 Feb 10;21(1):52
mTOR inhibitor, gemcitabine and PD-L1 antibody blockade combination therapy suppresses pancreatic cancer progression via metabolic reprogramming and immune microenvironment remodeling in Trp53(flox/+)LSL-Kras(G12D/+)Pdx-1-Cre murine models.
Qiu J, Feng M, Yang G, Cao Z, Liu Y, You L, Zhang T
Cancer letters 2023 Feb 1;554:216020
Cancer letters 2023 Feb 1;554:216020
GRAMD1/ASTER-mediated cholesterol transport promotes Smoothened cholesterylation at the endoplasmic reticulum.
Qiu ZP, Lin ZC, Hu A, Liu YB, Zeng WE, Zhao X, Shi XJ, Luo J, Song BL
The EMBO journal 2023 Feb 1;42(3):e111513
The EMBO journal 2023 Feb 1;42(3):e111513
HERC2 promotes inflammation-driven cancer stemness and immune evasion in hepatocellular carcinoma by activating STAT3 pathway.
Liu Y, Xu Q, Deng F, Zheng Z, Luo J, Wang P, Zhou J, Lu X, Zhang L, Chen Z, Zhang Q, Chen Q, Zuo D
Journal of experimental & clinical cancer research : CR 2023 Feb 1;42(1):38
Journal of experimental & clinical cancer research : CR 2023 Feb 1;42(1):38
Clinical Implications of a New DDX58 Pathogenic Variant That Causes Lupus Nephritis due to RIG-I Hyperactivation.
Peng J, Wang Y, Han X, Zhang C, Chen X, Jin Y, Yang Z, An Y, Zhang J, Liu Z, Chen Y, Gao E, Zhang Y, Xu F, Zheng C, Zhou Q, Liu Z
Journal of the American Society of Nephrology : JASN 2023 Feb 1;34(2):258-272
Journal of the American Society of Nephrology : JASN 2023 Feb 1;34(2):258-272
Molecular weight-dependent hyaluronic acid permeability and tight junction modulation in human buccal TR146 cell monolayers.
Park HY, Kweon DK, Kim JK
International journal of biological macromolecules 2023 Feb 1;227:182-192
International journal of biological macromolecules 2023 Feb 1;227:182-192
BMF-AS1/BMF Promotes Diabetic Vascular Calcification and Aging both In Vitro and In Vivo.
Lin X, Xiang QY, Li S, Song WL, Wang YJ, Ni YQ, Zhao Y, Li C, Wang Y, Li HH, Liang Z, Zhan JK, Liu YS
Aging and disease 2023 Feb 1;14(1):170-183
Aging and disease 2023 Feb 1;14(1):170-183
MiR-224-5p inhibits osteoblast differentiation and impairs bone formation by targeting Runx2 and Sp7.
Ding S, Ma Y, Yang J, Tang Y, Jin Y, Li L, Ma C
Cytotechnology 2023 Dec;75(6):505-516
Cytotechnology 2023 Dec;75(6):505-516
Phenylalanine diminishes M1 macrophage inflammation.
Zhang Q, Chen S, Guo Y, He F, Fu J, Ren W
Science China. Life sciences 2023 Dec;66(12):2862-2876
Science China. Life sciences 2023 Dec;66(12):2862-2876
JSI-124 inhibits cell proliferation and tumor growth by inducing autophagy and apoptosis in murine malignant mesothelioma.
Zhang C, Sun Q, Zhao J, Jiang N, Hao Y, Luo J, Karim S, Wu L, de Perrot M, Peng C, Zhao X
Molecular carcinogenesis 2023 Dec;62(12):1888-1901
Molecular carcinogenesis 2023 Dec;62(12):1888-1901
Guilu-Erxian-Glue alleviates Tripterygium wilfordii polyglycoside-induced oligoasthenospermia in rats by resisting ferroptosis via the Keap1/Nrf2/GPX4 signaling pathway.
Ding J, Lu B, Liu L, Zhong Z, Wang N, Li B, Sheng W, He Q
Pharmaceutical biology 2023 Dec;61(1):213-227
Pharmaceutical biology 2023 Dec;61(1):213-227
Integrating network pharmacology and experimental validation to decipher the mechanism of the Chinese herbal prescription modified Shen-Yan-Fang-Shuai formula in treating diabetic nephropathy.
Yu B, Zhou M, Dong Z, Zheng H, Zhao Y, Zhou J, Zhang C, Wei F, Yu G, Liu WJ, Liu H, Wang Y
Pharmaceutical biology 2023 Dec;61(1):1222-1233
Pharmaceutical biology 2023 Dec;61(1):1222-1233
Transcriptomic analysis reveals the regulatory mechanism underlying the indirubin-mediated amelioration of dextran sulfate sodium-induced colitis in mice.
Liu Z, Zhang JR, Huang YX, Li XY, Zhu HP, Yang RY, Chen S
Pharmaceutical biology 2023 Dec;61(1):1082-1093
Pharmaceutical biology 2023 Dec;61(1):1082-1093
NDRG1 promotes endothelial dysfunction and hypoxia-induced pulmonary hypertension by targeting TAF15.
Li C, Lv J, Wumaier G, Zhao Y, Dong L, Zeng Y, Zhu N, Zhang X, Wang J, Xia J, Li S
Precision clinical medicine 2023 Dec;6(4):pbad024
Precision clinical medicine 2023 Dec;6(4):pbad024
Glioblastoma cellular MAP4K1 facilitates tumor growth and disrupts T effector cell infiltration.
Sun JM, Fan HY, Zhu Y, Pan TT, Wu YP, Zhang DY, Hou XY
Life science alliance 2023 Dec;6(12)
Life science alliance 2023 Dec;6(12)
Hypoxia dissociates HDAC6/FOXO1 complex and aggregates them into nucleus to regulate autophagy and osteogenic differentiation.
Xu Y, Wang Y, Xiao H, Li Y
Journal of periodontal research 2023 Dec;58(6):1248-1260
Journal of periodontal research 2023 Dec;58(6):1248-1260
Role of GPX4 inhibition-mediated ferroptosis in the chemoresistance of ovarian cancer to Taxol in vitro.
Feng Q, Hao S, Fang P, Zhang P, Sheng X
Molecular biology reports 2023 Dec;50(12):10189-10198
Molecular biology reports 2023 Dec;50(12):10189-10198
TRPV4-mediated Ca(2+) deregulation causes mitochondrial dysfunction via the AKT/α-synuclein pathway in dopaminergic neurons.
Sun X, Kong J, Dong S, Kato H, Sato H, Hirofuji Y, Ito Y, Wang L, Kato TA, Torio M, Sakai Y, Ohga S, Fukumoto S, Masuda K
FASEB bioAdvances 2023 Dec;5(12):507-520
FASEB bioAdvances 2023 Dec;5(12):507-520
Targeting TRIM24 promotes neuroblastoma differentiation and decreases tumorigenicity via LSD1/CoREST complex.
Shi Q, Yu B, Zhang Y, Yang Y, Xu C, Zhang M, Chen G, Luo F, Sun B, Yang R, Li Y, Feng H
Cellular oncology (Dordrecht, Netherlands) 2023 Dec;46(6):1763-1775
Cellular oncology (Dordrecht, Netherlands) 2023 Dec;46(6):1763-1775
LncRNA H19-EZH2 interaction promotes liver fibrosis via reprogramming H3K27me3 profiles.
Li XJ, Zhou F, Li YJ, Xue XY, Qu JR, Fan GF, Liu J, Sun R, Wu JZ, Zheng Q, Liu RP
Acta pharmacologica Sinica 2023 Dec;44(12):2479-2491
Acta pharmacologica Sinica 2023 Dec;44(12):2479-2491
Dual network analysis of transcriptome data for discovery of new therapeutic targets in non-small cell lung cancer.
Bai Y, Zhou L, Zhang C, Guo M, Xia L, Tang Z, Liu Y, Deng S
Oncogene 2023 Dec;42(49):3605-3618
Oncogene 2023 Dec;42(49):3605-3618
Integrating network pharmacology and experimental models to examine the mechanisms of corosolic acid in preventing hepatocellular carcinoma progression through activation PERK-eIF2a-ATF4 signaling.
Tang F, Peng Y, Liu J, Gao W, Xu Y
Naunyn-Schmiedeberg's archives of pharmacology 2023 Dec;396(12):3671-3682
Naunyn-Schmiedeberg's archives of pharmacology 2023 Dec;396(12):3671-3682
Hyperhomocysteinemia lowers serum testosterone concentration via impairing testosterone production in Leydig cells.
Su Z, Liu Z, Lei W, Xia K, Xiao A, Hu Z, Zhou M, Zhu F, Tian J, Yang M, Wang D, Xiang AP, Nie J
Cell biology and toxicology 2023 Dec;39(6):3077-3100
Cell biology and toxicology 2023 Dec;39(6):3077-3100
Design, synthesis, and evaluation of novel benzoylhydrazone derivatives as Nur77 modulators with potent antitumor activity against hepatocellular carcinoma.
He F, Chen J, Zhao T, Wu Q, Yin N, Wang X, Zhong Y, Guo X, Qiu Y, Li B, Fang M, Wu Z
Journal of enzyme inhibition and medicinal chemistry 2023 Dec;38(1):2227777
Journal of enzyme inhibition and medicinal chemistry 2023 Dec;38(1):2227777
Molecular mechanisms in the miR-33a/LPPR4 pathway regulating unsaturated fatty acid synthesis in bovine mammary epithelial cells.
Wu Y, Zhang W, Wang Y, Lu Q, Zhou J, Chen Z, Yang Z, Loor JJ
Animal biotechnology 2023 Dec;34(7):2636-2648
Animal biotechnology 2023 Dec;34(7):2636-2648
Mannose antagonizes GSDME-mediated pyroptosis through AMPK activated by metabolite GlcNAc-6P.
Ai YL, Wang WJ, Liu FJ, Fang W, Chen HZ, Wu LZ, Hong X, Zhu Y, Zhang CX, Liu LY, Hong WB, Zhou B, Chen QT, Wu Q
Cell research 2023 Dec;33(12):904-922
Cell research 2023 Dec;33(12):904-922
Functional analysis of two SLC9A6 frameshift variants in lymphoblastoid cells from patients with Christianson syndrome.
He H, Zhang H, Chen H, He F, Yin F, Stauber T, Zou X, Peng J
CNS neuroscience & therapeutics 2023 Dec;29(12):4059-4069
CNS neuroscience & therapeutics 2023 Dec;29(12):4059-4069
Photobiomodulation reduces neuropathic pain after spinal cord injury by downregulating CXCL10 expression.
Zhang Z, Zhu Z, Zuo X, Wang X, Ju C, Liang Z, Li K, Zhang J, Luo L, Ma Y, Song Z, Li X, Li P, Quan H, Huang P, Yao Z, Yang N, Zhou J, Kou Z, Chen B, Ding T, Wang Z, Hu X
CNS neuroscience & therapeutics 2023 Dec;29(12):3995-4017
CNS neuroscience & therapeutics 2023 Dec;29(12):3995-4017
PP2Ac knockdown attenuates lipotoxicity‑induced pancreatic β‑cell dysfunction and apoptosis.
Zhang Z, Tong B, Liu J, Feng J, Song L, Wang H, Ke M, Xu C, Xu Y
Experimental and therapeutic medicine 2023 Dec;26(6):549
Experimental and therapeutic medicine 2023 Dec;26(6):549
FAM107A as a tumor suppressor in esophageal squamous carcinoma inhibits growth and metastasis.
Zhang J, Di S, Li M, Dong Y, Xie S, Gong T, Hu P, Jia Q, Fan B
Pathology, research and practice 2023 Dec;252:154945
Pathology, research and practice 2023 Dec;252:154945
Blue light photobiomodulation induced apoptosis by increasing ROS level and regulating SOCS3 and PTEN/PI3K/AKT pathway in osteosarcoma cells.
Yang J, Jiang H, Fu Q, Qin H, Li Y, Liu M
Journal of photochemistry and photobiology. B, Biology 2023 Dec;249:112814
Journal of photochemistry and photobiology. B, Biology 2023 Dec;249:112814
Insulin-like growth factor 2 mRNA-binding protein 2 is a therapeutic target in ovarian cancer.
Yuan J, Li X, Wang F, Liu H, Guan W, Xu G
Experimental biology and medicine (Maywood, N.J.) 2023 Dec;248(23):2198-2209
Experimental biology and medicine (Maywood, N.J.) 2023 Dec;248(23):2198-2209
Integrated analysis of murine cornea identifies JAK/STAT signaling pathway upregulated specifically in female Vitamin A Deficient mice.
Yu H, Wu J, Li K, Huang Y, Wu T, Wang L, Huang Y
Experimental eye research 2023 Dec;237:109714
Experimental eye research 2023 Dec;237:109714
HD-sEVs in bovine follicular fluid regulate granulosa cell apoptosis and estradiol secretion through the autophagy pathway.
Wang Y, Zhao Y, Ling Z, Luan D, Kang J, Dong X, Quan F
Theriogenology 2023 Dec;212:91-103
Theriogenology 2023 Dec;212:91-103
Integrated NLRP3, AIM2, NLRC4, Pyrin inflammasome activation and assembly drive PANoptosis.
Oh S, Lee J, Oh J, Yu G, Ryu H, Kim D, Lee S
Cellular & molecular immunology 2023 Dec;20(12):1513-1526
Cellular & molecular immunology 2023 Dec;20(12):1513-1526
Inhibition of USP1 ameliorates hypertensive nephropathy through regulating oxidative stress and ferroptosis: A precise treatment via SJB3-019A nanodelivery.
Hao F, Li Y, Zhang Y, Han Y, Shang J, Gan L, Zheng J, Zhang C
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2023 Dec;193:187-197
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2023 Dec;193:187-197
ENO1 promotes liver carcinogenesis through YAP1-dependent arachidonic acid metabolism.
Sun L, Suo C, Zhang T, Shen S, Gu X, Qiu S, Zhang P, Wei H, Ma W, Yan R, Chen R, Jia W, Cao J, Zhang H, Gao P
Nature chemical biology 2023 Dec;19(12):1492-1503
Nature chemical biology 2023 Dec;19(12):1492-1503
Scribble promotes fibrosis-dependent mechanisms of hepatocarcinogenesis by p53/PUMA-mediated glycolysis.
Wu Y, Song L, Kong J, Wen Q, Jiao J, Wang X, Li G, Xu X, Zhan L
Biochimica et biophysica acta. Molecular basis of disease 2023 Dec;1869(8):166823
Biochimica et biophysica acta. Molecular basis of disease 2023 Dec;1869(8):166823
Ceftazidime reduces cellular Skp2 to promote type-I interferon activity.
Qiao C, Huang F, He J, Wu Q, Zheng Z, Zhang T, Miao Y, Yuan Y, Chen X, Du Q, Xu Y, Wu D, Yu Z, Zheng H
Immunology 2023 Dec;170(4):527-539
Immunology 2023 Dec;170(4):527-539
CBX4 promotes antitumor immunity by suppressing Pdcd1 expression in T cells.
Ren L, Li Z, Zhou Y, Zhang J, Zhao Z, Wu Z, Zhao Y, Ju Y, Pang X, Sun X, Wang W, Zhang Y
Molecular oncology 2023 Dec;17(12):2694-2708
Molecular oncology 2023 Dec;17(12):2694-2708
The synthetic oleanane triterpenoid CDDO-2P-Im binds GRP78/BiP to induce unfolded protein response-mediated apoptosis in myeloma.
Luo G, Aldridge K, Chen T, Aslot V, Kim BG, Han EH, Singh N, Li S, Xiao TS, Sporn MB, Letterio JJ
Molecular oncology 2023 Dec;17(12):2526-2545
Molecular oncology 2023 Dec;17(12):2526-2545
Trigonelline inhibits tubular epithelial-mesenchymal transformation in diabetic kidney disease via targeting Smad7.
Gong M, Guo Y, Dong H, Wu W, Wu F, Lu F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115747
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115747
Cell-in-Cell-Mediated Entosis Reveals a Progressive Mechanism in Pancreatic Cancer.
Song J, Xu R, Zhang H, Xue X, Ruze R, Chen Y, Yin X, Wang C, Zhao Y
Gastroenterology 2023 Dec;165(6):1505-1521.e20
Gastroenterology 2023 Dec;165(6):1505-1521.e20
Propionate promotes gluconeogenesis by regulating mechanistic target of rapamycin (mTOR) pathway in calf hepatocytes.
Wang GY, Qin SL, Zheng YN, Geng HJ, Chen L, Yao JH, Deng L
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2023 Dec;15:88-98
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2023 Dec;15:88-98
The expression of Nramp1 modulates the uptake of Mycobacterium tuberculosis by macrophages through alternating inflammatory responses.
Meng C, Chen G, Wen D, Dong L, Cui X, Jing X, Cui J, Gao Y, Liu Y, Bu H, Wu C
Tuberculosis (Edinburgh, Scotland) 2023 Dec;143:102414
Tuberculosis (Edinburgh, Scotland) 2023 Dec;143:102414
Staphylococcus aureus planktonic but not biofilm environment induces an IFN-β macrophage immune response via the STING/IRF3 pathway.
Seebach E, Sonnenmoser G, Kubatzky KF
Virulence 2023 Dec;14(1):2254599
Virulence 2023 Dec;14(1):2254599
Oligomeric Aβ25-35 induces the tyrosine phosphorylation of PSD-95 by SrcPTKs in rat hippocampal CA1 subfield.
Wu GM, Du CP, Xu Y
The International journal of neuroscience 2023 Dec;133(8):888-895
The International journal of neuroscience 2023 Dec;133(8):888-895
Berberine ameliorates renal interstitial inflammation and fibrosis in mice with unilateral ureteral obstruction.
Tan E, Gao Z, Wang Q, Han B, Shi H, Wang L, Zhu G, Hou Y
Basic & clinical pharmacology & toxicology 2023 Dec;133(6):757-769
Basic & clinical pharmacology & toxicology 2023 Dec;133(6):757-769
The novel CDK9 inhibitor, XPW1, alone and in combination with BRD4 inhibitor JQ1, for the treatment of clear cell renal cell carcinoma.
Kuang Z, Guo K, Cao Y, Jiang M, Wang C, Wu Q, Hu G, Ao M, Huang M, Qin J, Zhao T, Lu S, Sun C, Li M, Wu T, Liu W, Fang M
British journal of cancer 2023 Dec;129(12):1915-1929
British journal of cancer 2023 Dec;129(12):1915-1929
Assessment of intestinal status in MPL(W515L) mutant myeloproliferative neoplasms mice model.
Zhu S, Xu K, Li S, Yu X, Liu Y, Zhang Q, Zeng L, Xu K, Fu C
International immunopharmacology 2023 Dec;125(Pt A):111091
International immunopharmacology 2023 Dec;125(Pt A):111091
Identification of TMEM53 as a novel SADS-CoV restriction factor that targets viral RNA-dependent RNA polymerase.
Yao YL, Luo Y, Wang Q, Geng R, Chen Y, Liu MQ, Li B, Chen J, Wu CG, Jia JK, Luo JY, He YT, Jiang TT, Zhu Y, Hu B, Zhou P, Shi ZL
Emerging microbes & infections 2023 Dec;12(2):2249120
Emerging microbes & infections 2023 Dec;12(2):2249120
SARS-CoV-2 Omicron subvariants exhibit distinct fusogenicity, but similar sensitivity, to pan-CoV fusion inhibitors.
Xia S, Wang L, Jiao F, Yu X, Xu W, Huang Z, Li X, Wang Q, Zhu Y, Man Q, Jiang S, Lu L
Emerging microbes & infections 2023 Dec;12(1):2178241
Emerging microbes & infections 2023 Dec;12(1):2178241
NSUN2-mediated M(5)c methylation of IRF3 mRNA negatively regulates type I interferon responses during various viral infections.
Wang H, Feng J, Zeng C, Liu J, Fu Z, Wang D, Wang Y, Zhang L, Li J, Jiang A, He M, Cao Y, Yan K, Tang H, Guo D, Xu K, Zhou X, Zhou L, Lan K, Zhou Y, Chen Y
Emerging microbes & infections 2023 Dec;12(1):2178238
Emerging microbes & infections 2023 Dec;12(1):2178238
PROS1, a clinical prognostic biomarker and tumor suppressor, is associated with immune cell infiltration in breast cancer: A bioinformatics analysis combined with experimental verification.
He T, Sun X, Wu C, Yao L, Zhang Y, Liu S, Jiang Y, Li Y, Wang M, Xu Y
Cellular signalling 2023 Dec;112:110918
Cellular signalling 2023 Dec;112:110918
Umbelliferone attenuates cisplatin-induced acute kidney injury by inhibiting oxidative stress and inflammation via NRF2.
Yang Z, Ning R, Liu Q, Zang R, Liu S, Sun S
Physiological reports 2023 Dec;11(23):e15879
Physiological reports 2023 Dec;11(23):e15879
Inducible nitric oxide synthase accelerates nonalcoholic fatty liver disease progression by regulating macrophage autophagy.
Jin G, Yao X, Liu D, Zhang J, Zhang X, Yang Y, Bi Y, Zhang H, Dong G, Tang H, Cheng S, Hong F, Si M
Immunity, inflammation and disease 2023 Dec;11(12):e1114
Immunity, inflammation and disease 2023 Dec;11(12):e1114
Inhibition of inflammation and infiltration of M2 macrophages in NSCLC through the ATF3/CSF1 axis: Role of miR-27a-3p.
Zhou B, Xu Y, Xu L, Kong Y, Li K, Chen B, Li J
International journal of experimental pathology 2023 Dec;104(6):292-303
International journal of experimental pathology 2023 Dec;104(6):292-303
Probiotic-fermented Qushi decoction alleviates reserpine-induced spleen deficiency syndrome by regulating spleen function and gut microbiota dysbiosis.
Zeng W, Chen Y, Zhang H, Peng L, Li Y, Liu B, Liang H, Du B, Li P
Journal of the science of food and agriculture 2023 Dec;103(15):7702-7711
Journal of the science of food and agriculture 2023 Dec;103(15):7702-7711
Bone Marrow-Derived GCA(+) Immune Cells Drive Alzheimer's Disease Progression.
Zhou R, Wang L, Chen L, Feng X, Zhou R, Xiang P, Wen J, Huang Y, Zhou H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(36):e2303402
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(36):e2303402
Prolonged sleep deprivation induces a cytokine-storm-like syndrome in mammals.
Sang D, Lin K, Yang Y, Ran G, Li B, Chen C, Li Q, Ma Y, Lu L, Cui XY, Liu Z, Lv SQ, Luo M, Liu Q, Li Y, Zhang EE
Cell 2023 Dec 7;186(25):5500-5516.e21
Cell 2023 Dec 7;186(25):5500-5516.e21
The Human Placental Amniotic Membrane Mesenchymal-Stromal-Cell-Derived Conditioned Medium Inhibits Growth and Promotes Apoptosis of Human Cholangiocarcinoma Cells In Vitro and In Vivo by Suppressing IL-6/JAK2/STAT3 Signaling.
Jantalika T, Manochantr S, Kheolamai P, Tantikanlayaporn D, Thongsepee N, Warnnissorn N, Saijuntha W, Pinlaor S, Tantrawatpan C
Cells 2023 Dec 7;12(24)
Cells 2023 Dec 7;12(24)
HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance.
Ling H, Li Y, Peng C, Yang S, Seto E
bioRxiv : the preprint server for biology 2023 Dec 7;
bioRxiv : the preprint server for biology 2023 Dec 7;
The Role of Cellular Senescence in Cyclophosphamide-Induced Primary Ovarian Insufficiency.
Xu Z, Takahashi N, Harada M, Kunitomi C, Kusamoto A, Koike H, Tanaka T, Sakaguchi N, Urata Y, Wada-Hiraike O, Hirota Y, Osuga Y
International journal of molecular sciences 2023 Dec 6;24(24)
International journal of molecular sciences 2023 Dec 6;24(24)
DHA and EPA Alleviate Epileptic Depression in PTZ-Treated Young Mice Model by Inhibiting Neuroinflammation through Regulating Microglial M2 Polarization and Improving Mitochondrial Metabolism.
Yang Y, Chen L, Zhang N, Zhao Y, Che H, Wang Y, Zhang T, Wen M
Antioxidants (Basel, Switzerland) 2023 Dec 6;12(12)
Antioxidants (Basel, Switzerland) 2023 Dec 6;12(12)
Study on the mechanism of Orthosiphon aristatus (Blume) Miq. in the treatment of hyperuricemia by microbiome combined with metabonomics.
Zhu C, Niu H, Bian M, Zhang X, Zhang X, Zhou Z
Journal of ethnopharmacology 2023 Dec 5;317:116805
Journal of ethnopharmacology 2023 Dec 5;317:116805
Pro-inflammatory Cytokines Promote the Occurrence and Development of Colitis-associated Colorectal Cancer by Inhibiting miR-615-5p.
Sun D, Gong L, Wang X, Chen S, Yi J, Liu X
Inflammatory bowel diseases 2023 Dec 5;29(12):1854-1864
Inflammatory bowel diseases 2023 Dec 5;29(12):1854-1864
Design, synthesis, and biological evaluation of novel 4,4'-bipyridine derivatives acting as CDK9-Cyclin T1 protein-protein interaction inhibitors against triple-negative breast cancer.
Gao G, Li J, Cao Y, Li X, Qian Y, Wang X, Li M, Qiu Y, Wu T, Wang L, Fang M
European journal of medicinal chemistry 2023 Dec 5;261:115858
European journal of medicinal chemistry 2023 Dec 5;261:115858
Mechanistic insights into the homo-dimerization of HOIL-1L and SHARPIN.
Zhang Y, Xu X, Wang Y, Wang Y, Zhou X, Pan L
Biochemical and biophysical research communications 2023 Dec 31;689:149239
Biochemical and biophysical research communications 2023 Dec 31;689:149239
Super-enhancer-associated EEPD1 facilitates EMT-mediated metastasis by regulating the PI3K/AKT/mTOR pathway in gastric cancer.
Jin Y, Xia Y, Du H, Xiang T, Lan B, Wei S, Li H, Huang H
Biochemical and biophysical research communications 2023 Dec 31;689:149188
Biochemical and biophysical research communications 2023 Dec 31;689:149188
Soyasaponin I alleviates hypertensive intracerebral hemorrhage by inhibiting the renin-angiotensin-aldosterone system.
Li W, Li SG, Li L, Yang LJ, Li ZS, Li X, Ye AY, Xiong Y, Zhang Y, Xiong YY
Clinical and experimental hypertension (New York, N.Y. : 1993) 2023 Dec 31;45(1):2177667
Clinical and experimental hypertension (New York, N.Y. : 1993) 2023 Dec 31;45(1):2177667
Exopolysaccharide from Weissella confusa J4-1 inhibits colorectal cancer via induction of cell cycle arrest.
Liu L, Du Y, Du Y, Yan W, Li Y, Cui K, Li Z, Yu P, Zhang W, Feng J, Ma W, Zhao H
International journal of biological macromolecules 2023 Dec 31;253(Pt 8):127625
International journal of biological macromolecules 2023 Dec 31;253(Pt 8):127625
An injectable and light curable hyaluronic acid composite gel with anti-biofilm, anti-inflammatory and pro-healing characteristics for accelerating infected wound healing.
Lin X, Fu T, Lei Y, Xu J, Wang S, He F, Xie Z, Zhang L
International journal of biological macromolecules 2023 Dec 31;253(Pt 5):127190
International journal of biological macromolecules 2023 Dec 31;253(Pt 5):127190
Astragaloside IV enhances the sensitivity of breast cancer stem cells to paclitaxel by inhibiting stemness.
Huang P, Li H, Ren L, Xie H, Chen L, Liang Y, Hu Y, Selistre-de-Araujo HS, Boussios S, Jhawar SR, Cui R, Zuo Q, Chen Q
Translational cancer research 2023 Dec 31;12(12):3703-3717
Translational cancer research 2023 Dec 31;12(12):3703-3717
IGF2BP1 enhances the stability of SIK2 mRNA through m(6)A modification to promote non-small cell lung cancer progression.
Xu Y, Xu L, Kong Y, Li K, Li J, Xu F, Liang S, Chen B
Biochemical and biophysical research communications 2023 Dec 3;684:149113
Biochemical and biophysical research communications 2023 Dec 3;684:149113
Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy.
Cheng J, Yan Z, Jiang K, Liu C, Xu D, Lyu X, Hu X, Zhang S, Zhou Y, Li J, Zhao Y
Journal of medicinal chemistry 2023 Dec 28;66(24):16991-17025
Journal of medicinal chemistry 2023 Dec 28;66(24):16991-17025
RTKN2 knockdown alleviates the malignancy of breast cancer cells by regulating the Wnt/β-catenin pathway.
Zhang X, Wang J, Li H
Scientific reports 2023 Dec 27;13(1):23023
Scientific reports 2023 Dec 27;13(1):23023
DPP4 Regulates the Th17/IL-17 Axis and Accelerates Epithelial Mesenchymal Transition to Promote Ovalbumin-Induced Asthma in Female C57BL/6J Mice.
Li L, Ling F, Li R, Jiang Y, Long H, Xiao B, Wu J, Long Z, Ma L
Frontiers in bioscience (Landmark edition) 2023 Dec 26;28(12):342
Frontiers in bioscience (Landmark edition) 2023 Dec 26;28(12):342
Biochemical Toxicological Study of Insulin Overdose in Rats: A Forensic Perspective.
Bian C, He X, Wang Q, Zheng Z, Zhang Y, Xiong H, Li Y, Zhao M, Li J
Toxics 2023 Dec 23;12(1)
Toxics 2023 Dec 23;12(1)
Circulating small extracellular vesicles microRNAs plus CA-125 for treatment stratification in advanced ovarian cancer.
Zhou X, Liu M, Sun L, Cao Y, Tan S, Luo G, Liu T, Yao Y, Xiao W, Wan Z, Tang J
Journal of translational medicine 2023 Dec 22;21(1):927
Journal of translational medicine 2023 Dec 22;21(1):927
Phosphorylated Adapter RNA Export Protein Is Methylated at Lys 381 by an Methyltransferase-like 21C (METTL21C).
Ke M, Yu X, Sun Y, Han S, Wang L, Zhang T, Zeng W, Lu H
International journal of molecular sciences 2023 Dec 21;25(1)
International journal of molecular sciences 2023 Dec 21;25(1)
Schistosome egg-derived extracellular vesicles deliver Sja-miR-71a inhibits host macrophage and neutrophil extracellular traps via targeting Sema4D.
Liao Y, Zhu Z, Liu Y, Wu J, Li D, Li Z, Xu J, Yang R, Wang L
Cell communication and signaling : CCS 2023 Dec 21;21(1):366
Cell communication and signaling : CCS 2023 Dec 21;21(1):366
Choroid plexus mast cells drive tumor-associated hydrocephalus.
Li Y, Di C, Song S, Zhang Y, Lu Y, Liao J, Lei B, Zhong J, Guo K, Zhang N, Su S
Cell 2023 Dec 21;186(26):5719-5738.e28
Cell 2023 Dec 21;186(26):5719-5738.e28
Identification and validation of key biomarkers associated with macrophages in nonalcoholic fatty liver disease based on hdWGCNA and machine learning.
Li R, Zhao M, Miao C, Shi X, Lu J
Aging 2023 Dec 21;15(24):15451-15472
Aging 2023 Dec 21;15(24):15451-15472
BACH1 controls hepatic insulin signaling and glucose homeostasis in mice.
Jin J, He Y, Guo J, Pan Q, Wei X, Xu C, Qi Z, Li Q, Ma S, Lin J, Jiang N, Ma J, Wang X, Jiang L, Ding Q, Osto E, Zhi X, Meng D
Nature communications 2023 Dec 21;14(1):8428
Nature communications 2023 Dec 21;14(1):8428
Nobiletin Ameliorates Hepatic Lipid Deposition, Oxidative Stress, and Inflammation by Mechanisms That Involve the Nrf2/NF-κB Axis in Nonalcoholic Fatty Liver Disease.
Fan C, Ling-Hu A, Sun D, Gao W, Zhang C, Duan X, Li H, Tian W, Yu Q, Ke Z
Journal of agricultural and food chemistry 2023 Dec 20;71(50):20105-20117
Journal of agricultural and food chemistry 2023 Dec 20;71(50):20105-20117
Vidofludimus inhibits porcine reproductive and respiratory syndrome virus infection by targeting dihydroorotate dehydrogenase.
Yang Y, Gao Y, Zhang L, Liu X, Sun Y, Bai J, Jiang P
Veterinary research 2023 Dec 20;54(1):124
Veterinary research 2023 Dec 20;54(1):124
Hedgehog-Gli1-derived exosomal circ-0011536 mediates peripheral neural remodeling in pancreatic cancer by modulating the miR-451a/VGF axis.
Dai W, Wu X, Li J, Tang W, Wang Y, Xu W, Han D, Xu X, Xu X
Journal of experimental & clinical cancer research : CR 2023 Dec 2;42(1):329
Journal of experimental & clinical cancer research : CR 2023 Dec 2;42(1):329
Insights into the ISG15 transfer cascade by the UBE1L activating enzyme.
Wallace I, Baek K, Prabu JR, Vollrath R, von Gronau S, Schulman BA, Swatek KN
Nature communications 2023 Dec 2;14(1):7970
Nature communications 2023 Dec 2;14(1):7970
The nonstructural protein 1 of respiratory syncytial virus hijacks host mitophagy as a novel mitophagy receptor to evade the type I IFN response in HEp-2 cells.
Cheng J, Wang Y, Yin L, Liang W, Zhang J, Ma C, Zhang Y, Liu B, Wang J, Zhao W, Li M, Wei L
mBio 2023 Dec 19;14(6):e0148023
mBio 2023 Dec 19;14(6):e0148023
Gss deficiency causes age-related fertility impairment via ROS-triggered ferroptosis in the testes of mice.
Zhu H, Cheng Y, Wang X, Yang X, Liu M, Liu J, Liu S, Wang H, Zhang A, Li R, Ye C, Zhang J, Gao J, Fu X, Wu B
Cell death & disease 2023 Dec 19;14(12):845
Cell death & disease 2023 Dec 19;14(12):845
ER Stress-Perturbed Intracellular Protein O-GlcNAcylation Aggravates Podocyte Injury in Diabetes Nephropathy.
Song S, Hu T, Shi X, Jin Y, Liu S, Li X, Zou W, Wang C
International journal of molecular sciences 2023 Dec 18;24(24)
International journal of molecular sciences 2023 Dec 18;24(24)
The HSP40 family chaperone isoform DNAJB6b prevents neuronal cells from tau aggregation.
Chang YL, Yang CC, Huang YY, Chen YA, Yang CW, Liao CY, Li H, Wu CS, Lin CH, Teng SC
BMC biology 2023 Dec 18;21(1):293
BMC biology 2023 Dec 18;21(1):293
Fluorinated Cell-Penetrating Peptide for Co-Delivering siHIF-1α and Sorafenib to Enhance In Vitro Anti-Tumor Efficacy.
Wan Y, Yang Y, Lai Q, Wang W, Wu M, Feng S
Pharmaceutics 2023 Dec 16;15(12)
Pharmaceutics 2023 Dec 16;15(12)
Glycyrrhetinic acid attenuates endoplasmic reticulum stress-induced hepatocyte apoptosis via CHOP/DR5/Caspase 8 pathway in cholestasis.
Zou B, Zhang S, Zhao J, Song G, Weng F, Xu X, Li F, Jin J, Yan D, Huang K, Liu C, Li Y, Qiu F
European journal of pharmacology 2023 Dec 15;961:176193
European journal of pharmacology 2023 Dec 15;961:176193
GPR146 regulates pulmonary vascular remodeling by promoting pulmonary artery smooth muscle cell proliferation through 5-lipoxygenase.
Huang J, Xie Y, Chen B, Xia Y, Jiang Y, Sun Z, Liu Y
European journal of pharmacology 2023 Dec 15;961:176123
European journal of pharmacology 2023 Dec 15;961:176123
Glutathione-responsive PROTAC for targeted degradation of ERα in breast cancer cells.
Zhou Z, Fan H, Yu D, Shi F, Li Q, Zhang Z, Wang X, Zhang X, Dong C, Sun H, Mi W
Bioorganic & medicinal chemistry 2023 Dec 15;96:117526
Bioorganic & medicinal chemistry 2023 Dec 15;96:117526
Targeting AKT induced Ferroptosis through FTO/YTHDF2-dependent GPX4 m6A methylation up-regulating and degradating in colorectal cancer.
Zhang G, Mi W, Wang C, Li J, Zhang Y, Liu N, Jiang M, Jia G, Wang F, Yang G, Zhang L, Wang J, Fu Y, Zhang Y
Cell death discovery 2023 Dec 15;9(1):457
Cell death discovery 2023 Dec 15;9(1):457
Adoptive transfer of immature dendritic cells with high HO-1 expression delays the onset of T1DM in NOD mice.
Yang X, Ma Z, Tan X, Shi Y, Yuan M, Chen G, Luo X, Hou L
Life sciences 2023 Dec 15;335:122273
Life sciences 2023 Dec 15;335:122273
A Study on the Pharmacological Effects and Mechanism of Rhodojaponin III in Rheumatoid Arthritis.
Liu X, Li S, Xu Y, Mei W, Zhou R
Frontiers in bioscience (Landmark edition) 2023 Dec 15;28(12):337
Frontiers in bioscience (Landmark edition) 2023 Dec 15;28(12):337
Identification of ANXA3 as a biomarker associated with pyroptosis in ischemic stroke.
Liu L, Cai Y, Deng C
European journal of medical research 2023 Dec 15;28(1):596
European journal of medical research 2023 Dec 15;28(1):596
Autophagy is involved in degradation of AQP1 in response to an acute decrement in tonicity.
Guo X, Xu L, Kong Y, Li M, Zhai Q, Liang B, Zhao X, Long L, Huang M, Wang W, Li C
iScience 2023 Dec 15;26(12):108485
iScience 2023 Dec 15;26(12):108485
Foxp3-mediated blockage of ryanodine receptor 2 underlies contact-based suppression by regulatory T cells.
Wang X, Geng S, Meng J, Kang N, Liu X, Xu Y, Lyu H, Xu Y, Xu X, Song X, Zhang B, Wang X, Nuerbulati N, Zhang Z, Zhai D, Mao X, Sun R, Wang X, Wang R, Guo J, Chen SRW, Zhou X, Xia T, Qi H, Hu X, Shi Y
The Journal of clinical investigation 2023 Dec 15;133(24)
The Journal of clinical investigation 2023 Dec 15;133(24)
IL20RB signaling enhances stemness and chemotherapy resistance in pancreatic cancer.
Li XH, Huang GZ, Xu ZL, Zhao CY, Dong XY, Cui BK, Lin XJ
Journal of translational medicine 2023 Dec 14;21(1):911
Journal of translational medicine 2023 Dec 14;21(1):911
Cyclosporine A alleviates colitis by inhibiting the formation of neutrophil extracellular traps via the regulating pentose phosphate pathway.
Xu C, Ye Z, Jiang W, Wang S, Zhang H
Molecular medicine (Cambridge, Mass.) 2023 Dec 13;29(1):169
Molecular medicine (Cambridge, Mass.) 2023 Dec 13;29(1):169
Alleviation of ischemia-reperfusion induced renal injury by chemically modified SOD2 mRNA delivered via lipid nanoparticles.
Hou Y, Lin S, Xia J, Zhang Y, Yin Y, Huang M, Xu Y, Yang W, Zhu Y
Molecular therapy. Nucleic acids 2023 Dec 12;34:102067
Molecular therapy. Nucleic acids 2023 Dec 12;34:102067
Cytomegalovirus-vectored COVID-19 vaccines elicit neutralizing antibodies against the SARS-CoV-2 Omicron variant (BA.2) in mice.
Liu J, Jaijyan DK, Chen Y, Feng C, Yang S, Xu Z, Zhan N, Hong C, Li S, Cheng T, Zhu H
Microbiology spectrum 2023 Dec 12;11(6):e0246323
Microbiology spectrum 2023 Dec 12;11(6):e0246323
NLRP3 inflammasome-mediated pyroptosis involvement in cadmium exposure-induced cognitive deficits via the Sirt3-mtROS axis.
Wang D, Wu Y, Sun S, Zhao P, Zhou X, Liang C, Ma Y, Li S, Zhu X, Hao X, Shi J, Fan H
The Science of the total environment 2023 Dec 10;903:166478
The Science of the total environment 2023 Dec 10;903:166478
Inhibition of the lncRNA 585189 prevents podocyte injury and mitochondria dysfunction by promoting hnRNP A1 and SIRT1 in diabetic nephropathy.
Chen H, Liu Y, Zhang T, Huang T, Lang Y, Sheng Q, Liu Y, Kong Z, Gao Y, Lu S, Yang M, Li X, Wang R, Lv Z
Molecular and cellular endocrinology 2023 Dec 1;578:112065
Molecular and cellular endocrinology 2023 Dec 1;578:112065
Restoring System xc- activity by xCT overexpression inhibited neuronal ferroptosis and improved neurological deficits after experimental subarachnoid hemorrhage.
Cao C, Lu T, Cheng Q, Cui G, Wang Z, Li X, Li H, Gao H, Shen H, Sun Q
Brain research 2023 Dec 1;1820:148556
Brain research 2023 Dec 1;1820:148556
CRISPR screening identifies the deubiquitylase ATXN3 as a PD-L1-positive regulator for tumor immune evasion.
Wang S, Iyer R, Han X, Wei J, Li N, Cheng Y, Zhou Y, Gao Q, Zhang L, Yan M, Sun Z, Fang D
The Journal of clinical investigation 2023 Dec 1;133(23)
The Journal of clinical investigation 2023 Dec 1;133(23)
LY6E is a pan-coronavirus restriction factor in the respiratory tract.
Mar KB, Wells AI, Caballero Van Dyke MC, Lopez AH, Eitson JL, Fan W, Hanners NW, Evers BM, Shelton JM, Schoggins JW
Nature microbiology 2023 Aug;8(8):1587-1599
Nature microbiology 2023 Aug;8(8):1587-1599
Exosomal PPARγ derived from macrophages suppresses LPS-induced peritonitis by negative regulation of CD14/TLR4 axis.
Meng M, Lu M, Feng J, Zhou X, Meng P, Chen L, Zou X, Liu X, Liu L, Gao X, Zhang Y
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Aug;72(8):1567-1581
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Aug;72(8):1567-1581
Retrotransposons hijack alt-EJ for DNA replication and eccDNA biogenesis.
Yang F, Su W, Chung OW, Tracy L, Wang L, Ramsden DA, Zhang ZZZ
Nature 2023 Aug;620(7972):218-225
Nature 2023 Aug;620(7972):218-225
Scutellarin Acts via MAPKs Pathway to Promote M2 Polarization of Microglial Cells.
Chen HL, Yang L, Zhang XL, Jia QY, Duan ZD, Li JJ, Zheng LY, Liu TT, Qi Z, Yuan Y, Wu CY
Molecular neurobiology 2023 Aug;60(8):4304-4323
Molecular neurobiology 2023 Aug;60(8):4304-4323
The therapeutic effect of tanshinone IIA in mouse astrocytes after treatment with Angiostrongylus cantonensis fifth-stage larval excretory-secretory products.
Chen KY, Chen YJ, Cheng CJ, Jhan KY, Chiu CH, Wang LC
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2023 Aug;56(4):853-862
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2023 Aug;56(4):853-862
Aquaporin 1 is a prognostic marker and inhibits tumour progression through downregulation of Snail expression in intrahepatic cholangiocarcinoma.
Zhuang MQ, Jiang XL, Liu WD, Xie QH, Wang P, Dong LW, Hu HP, Zhou HB, Zhou YB
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2023 Aug;55(8):1133-1140
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2023 Aug;55(8):1133-1140
The G allele of SNP rs3922 reduces the binding affinity between IGF2BP3 and CXCR5 correlating with a lower antibody production.
Duan Z, Ma L, Jin J, Ma L, Ye L, Wu J, Luo Y
European journal of immunology 2023 Aug;53(8):e2250261
European journal of immunology 2023 Aug;53(8):e2250261
Dipyridamole enhances the anti-cancer ability of aspirin against colorectal cancer by inducing apoptosis in an unfolded protein response-dependent manner.
Huang S, Zhang NQ, Xu CJ, Huang WQ, Li DX, Li J, Yao LL, Sundquist K, Sundquist J, Jiang SH, Xing X, Hu LP, Zhang ZG, Ji J, Zhang XL
Cellular oncology (Dordrecht, Netherlands) 2023 Aug;46(4):953-967
Cellular oncology (Dordrecht, Netherlands) 2023 Aug;46(4):953-967
Glutamine metabolic microenvironment drives M2 macrophage polarization to mediate trastuzumab resistance in HER2-positive gastric cancer.
Hu X, Ma Z, Xu B, Li S, Yao Z, Liang B, Wang J, Liao W, Lin L, Wang C, Zheng S, Wu Q, Huang Q, Yu L, Wang F, Shi M
Cancer communications (London, England) 2023 Aug;43(8):909-937
Cancer communications (London, England) 2023 Aug;43(8):909-937
Cell Cycle-Related FAM64A Could be Activated by TGF-β Signaling to Promote Glioma Progression.
Fu M, Zhang J, Zhang L, Feng Y, Fang X, Zhang J, Wen W, Hua W, Mao Y
Cellular and molecular neurobiology 2023 Aug;43(6):2975-2987
Cellular and molecular neurobiology 2023 Aug;43(6):2975-2987
SARS-CoV-2 Nsp8 induces mitophagy by damaging mitochondria.
Zong S, Wu Y, Li W, You Q, Peng Q, Wang C, Wan P, Bai T, Ma Y, Sun B, Qiao J
Virologica Sinica 2023 Aug;38(4):520-530
Virologica Sinica 2023 Aug;38(4):520-530
Dickkopf-1 promotes vascular smooth muscle cell foam cell formation and atherosclerosis development through CYP4A11/SREBP2/ABCA1.
Li X, Zheng T, Zhang Y, Zhao Y, Liu F, Dai S, Liu X, Zhang M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Aug;37(8):e23048
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Aug;37(8):e23048
Metal-ion transporter SLC39A8 is required for brain manganese uptake and accumulation.
Liu Q, Jenkitkasemwong S, Prami TA, McCabe SM, Zhao N, Hojyo S, Fukada T, Knutson MD
The Journal of biological chemistry 2023 Aug;299(8):105078
The Journal of biological chemistry 2023 Aug;299(8):105078
PTBP1 suppresses porcine epidemic diarrhea virus replication via inducing protein degradation and IFN production.
Qin W, Kong N, Zhang Y, Wang C, Dong S, Zhai H, Zhai X, Yang X, Ye C, Ye M, Tong W, Liu C, Yu L, Zheng H, Yu H, Zhang W, Lan D, Tong G, Shan T
The Journal of biological chemistry 2023 Aug;299(8):104987
The Journal of biological chemistry 2023 Aug;299(8):104987
HIV-1 subtype B Tat enhances NOTCH3 signaling in astrocytes to mediate oxidative stress, inflammatory response, and neuronal apoptosis.
Gao L, Sun W, Zhang D, Shang Y, Li L, Tao W, Zhang L, Liu H
Journal of neurovirology 2023 Aug;29(4):479-491
Journal of neurovirology 2023 Aug;29(4):479-491
Role of Escin in breast cancer therapy: potential mechanism for inducing ferroptosis and synergistic antitumor activity with cisplatin.
Li C, He Z, Yao F, Liao S, Sun K, Sun S, Li Z, Wang Z
Apoptosis : an international journal on programmed cell death 2023 Aug;28(7-8):1154-1167
Apoptosis : an international journal on programmed cell death 2023 Aug;28(7-8):1154-1167
Identification and validation of SOCS1/2/3/4 as potential prognostic biomarkers and correlate with immune infiltration in glioblastoma.
Dai L, Han Y, Yang Z, Zeng Y, Liang W, Shi Z, Tao Y, Liang X, Liu W, Zhou S, Xing Z, Hu W, Wang X
Journal of cellular and molecular medicine 2023 Aug;27(15):2194-2214
Journal of cellular and molecular medicine 2023 Aug;27(15):2194-2214
Overexpression of hepatic pescadillo 1 in obesity induces lipid dysregulation by inhibiting autophagy.
Zhou J, Lu Y, Lin Y, Li C, Liu J, Jiang Z, Chen K
Translational research : the journal of laboratory and clinical medicine 2023 Aug;258:1-15
Translational research : the journal of laboratory and clinical medicine 2023 Aug;258:1-15
ETS1 Ameliorates Hyperoxia-Induced Bronchopulmonary Dysplasia in Mice by Activating Nrf2/HO-1 Mediated Ferroptosis.
Yang M, Chen Y, Huang X, Shen F, Meng Y
Lung 2023 Aug;201(4):425-441
Lung 2023 Aug;201(4):425-441
Profilin1 Regulates Trophoblast Invasion and Macrophage Differentiation.
Chen X, Song QL, Wang JY, Ji R, Li ZH, Cao ML, Mu XF, Guo DY, Zhang Y, Yang J
The American journal of pathology 2023 Aug;193(8):1059-1071
The American journal of pathology 2023 Aug;193(8):1059-1071
Contrasting effects of filamin A and B proteins in modulating filovirus entry.
Shepley-McTaggart A, Liang J, Ding Y, Djurkovic MA, Kriachun V, Shtanko O, Sunyer O, Harty RN
PLoS pathogens 2023 Aug;19(8):e1011595
PLoS pathogens 2023 Aug;19(8):e1011595
N protein of PEDV plays chess game with host proteins by selective autophagy.
Zhai X, Kong N, Zhang Y, Song Y, Qin W, Yang X, Ye C, Ye M, Tong W, Liu C, Zheng H, Yu H, Zhang W, Yang X, Zhang G, Tong G, Shan T
Autophagy 2023 Aug;19(8):2338-2352
Autophagy 2023 Aug;19(8):2338-2352
Mesenchymal Stem Cell-Derived Exosomal miR-150-3p Affects Intracerebral Hemorrhage By Regulating TRAF6/NF-κB Axis, Gut Microbiota and Metabolism.
Sun J, Xu G
Stem cell reviews and reports 2023 Aug;19(6):1907-1921
Stem cell reviews and reports 2023 Aug;19(6):1907-1921
Death-associated protein kinase 1 is associated with cognitive dysfunction in major depressive disorder.
Li XH, Zhu HC, Cui XM, Wang W, Yang L, Wang LB, Hu NW, Duan DX
Neural regeneration research 2023 Aug;18(8):1795-1801
Neural regeneration research 2023 Aug;18(8):1795-1801
Potential targets and mechanisms of photobiomodulation for spinal cord injury.
Ju C, Ma YG, Zuo XS, Wang XK, Song ZW, Zhang ZH, Zhu ZJ, Li X, Liang ZW, Ding T, Wang Z, Hu XY
Neural regeneration research 2023 Aug;18(8):1782-1788
Neural regeneration research 2023 Aug;18(8):1782-1788
High SNRPA1 expression leads to poor prognosis in patients with lung adenocarcinoma.
Yang JJ, Yang YJ, Gu YL, Tong L, Liu YF, Zhang JG
The clinical respiratory journal 2023 Aug;17(8):719-732
The clinical respiratory journal 2023 Aug;17(8):719-732
Schwann cell-derived amphiregulin enhances nerve regeneration via supporting the proliferation and migration of Schwann cells and the elongation of axons.
Chen S, Chen Q, Zhang X, Shen Y, Shi X, Dai X, Yi S
Journal of neurochemistry 2023 Aug;166(4):678-691
Journal of neurochemistry 2023 Aug;166(4):678-691
1,8-Cineole ameliorates diabetic retinopathy by inhibiting retinal pigment epithelium ferroptosis via PPAR-γ/TXNIP pathways.
Liu Z, Gan S, Fu L, Xu Y, Wang S, Zhang G, Pan D, Tao L, Shen X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Aug;164:114978
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Aug;164:114978
AF9 sustains glycolysis in colorectal cancer via H3K9ac-mediated PCK2 and FBP1 transcription.
He X, Zhong X, Fang Y, Hu Z, Chen Z, Wang Y, Huang H, Zhao S, Li D, Wei P
Clinical and translational medicine 2023 Aug;13(8):e1352
Clinical and translational medicine 2023 Aug;13(8):e1352
PRSS2 regulates EMT and metastasis via MMP-9 in gastric cancer.
Wang F, Yi J, Chen Y, Bai X, Lu C, Feng S, Zhou X
Acta histochemica 2023 Aug;125(6):152071
Acta histochemica 2023 Aug;125(6):152071
Ficolin A knockout alleviates sepsis-induced severe lung injury in mice by restoring gut Akkermansia to inhibit S100A4/STAT3 pathway.
Wu X, Xuan W, Yang X, Liu W, Zhang H, Jiang G, Cao B, Jiang Y
International immunopharmacology 2023 Aug;121:110548
International immunopharmacology 2023 Aug;121:110548
Astragaloside IV protects LO2 cells from oxidative damage caused by radiation-induced bystander effect through Akt/Nrf2 pathway.
Wan D, Zhu Z, Zhou J, Deng Z, Lei P, Liu Q, Sun X, Huang B
Toxicology research 2023 Aug;12(4):635-647
Toxicology research 2023 Aug;12(4):635-647
ROS Scavenging Nanozyme Modulates Immunosuppression for Sensitized Cancer Immunotherapy.
Mo W, Liu S, Zhao X, Wei F, Li Y, Sheng X, Cao W, Ding M, Zhang W, Chen X, Meng L, Yao S, Diao W, Wei H, Guo H
Advanced healthcare materials 2023 Aug;12(21):e2300191
Advanced healthcare materials 2023 Aug;12(21):e2300191
Inhibition of VEGFR2 and EGFR signaling cooperatively suppresses the proliferation of oral squamous cell carcinoma.
Onda M, Ota A, Ito K, Ono T, Karnan S, Kato M, Kondo S, Furuhashi A, Hayashi T, Hosokawa Y, Kazaoka Y
Cancer medicine 2023 Aug;12(15):16416-16430
Cancer medicine 2023 Aug;12(15):16416-16430
YAP/STAT3 inhibited CD8(+) T cells activity in the breast cancer immune microenvironment by inducing M2 polarization of tumor-associated macrophages.
Wang C, Shen N, Guo Q, Tan X, He S
Cancer medicine 2023 Aug;12(15):16295-16309
Cancer medicine 2023 Aug;12(15):16295-16309
Angiopoietin-like 4 induces head and neck squamous cell carcinoma cell migration through the NRP1/ABL1/PXN pathway.
Hefni E, Menon D, Ma T, Asiedu EB, Sultan A, Meiller T, Schneider A, Sodhi A, Montaner S
Cellular signalling 2023 Aug;108:110697
Cellular signalling 2023 Aug;108:110697
Curcumin enhances elvitegravir concentration and alleviates oxidative stress and inflammatory response.
Godse S, Zhou L, Sinha N, Kodidela S, Kumar A, Singh UP, Kumar S
Research square 2023 Aug 9;
Research square 2023 Aug 9;
Mitochondrial carrier 1 (MTCH1) governs ferroptosis by triggering the FoxO1-GPX4 axis-mediated retrograde signaling in cervical cancer cells.
Wang X, Ji Y, Qi J, Zhou S, Wan S, Fan C, Gu Z, An P, Luo Y, Luo J
Cell death & disease 2023 Aug 8;14(8):508
Cell death & disease 2023 Aug 8;14(8):508
Hesperidin may improve depressive symptoms by binding NLRP3 and influencing the pyroptosis pathway in a rat model.
Cao H, Yang D, Nie K, Lin R, Peng L, Zhou X, Zhang M, Zeng Y, Liu L, Huang W
European journal of pharmacology 2023 Aug 5;952:175670
European journal of pharmacology 2023 Aug 5;952:175670
SQLE promotes pancreatic cancer growth by attenuating ER stress and activating lipid rafts-regulated Src/PI3K/Akt signaling pathway.
Xu R, Song J, Ruze R, Chen Y, Yin X, Wang C, Zhao Y
Cell death & disease 2023 Aug 4;14(8):497
Cell death & disease 2023 Aug 4;14(8):497
Identification of NOX4 as a New Biomarker in Hepatocellular Carcinoma and Its Effect on Sorafenib Therapy.
Li HZ, Liu QQ, Chang DH, Li SX, Yang LT, Zhou P, Deng JB, Huang CH, Xiao YD
Biomedicines 2023 Aug 4;11(8)
Biomedicines 2023 Aug 4;11(8)
Ficolin B secreted by alveolar macrophage exosomes exacerbates bleomycin-induced lung injury via ferroptosis through the cGAS-STING signaling pathway.
Wu X, Jiang Y, Li R, Xia Y, Li F, Zhao M, Li G, Tan X
Cell death & disease 2023 Aug 30;14(8):577
Cell death & disease 2023 Aug 30;14(8):577
Tissue pleiotropic effect of biotin and prebiotic supplementation in established obesity.
Voland L, Yuan M, Lecoutre S, Debédat J, Pelloux V, Pradeau M, Coles E, Merabtene F, Zhang C, Mardinoglu A, Le Roy T, Soula H, Clément K
American journal of physiology. Endocrinology and metabolism 2023 Aug 30;
American journal of physiology. Endocrinology and metabolism 2023 Aug 30;
Optimized allotopic expression of mitochondrial ND6 transgene restored complex I and apoptosis deficiencies caused by LHON-linked ND6 14484T > C mutation.
Wang J, Ji Y, Ai C, Chen JR, Gan D, Zhang J, Mo JQ, Guan MX
Journal of biomedical science 2023 Aug 3;30(1):63
Journal of biomedical science 2023 Aug 3;30(1):63
MicroRNA-144-3p protects against chemotherapy-induced apoptosis of ovarian granulosa cells and activation of primordial follicles by targeting MAP3K9.
Liu M, Xiao B, Zhu Y, Chen M, Huang J, Guo H, Wang F
European journal of medical research 2023 Aug 3;28(1):264
European journal of medical research 2023 Aug 3;28(1):264
MATR3-antisense LINE1 RNA meshwork scaffolds higher-order chromatin organization.
Zhang Y, Cao X, Gao Z, Ma X, Wang Q, Xu X, Cai X, Zhang Y, Zhang Z, Wei G, Wen B
EMBO reports 2023 Aug 3;24(8):e57550
EMBO reports 2023 Aug 3;24(8):e57550
Hedgehog receptors exert immune-surveillance roles in the epidermis across species.
Wang Q, Fu R, Li G, Xiong S, Zhu Y, Zhang H
Cell reports 2023 Aug 29;42(8):112929
Cell reports 2023 Aug 29;42(8):112929
SLC38A5 aggravates DC-mediated psoriasiform skin inflammation via potentiating lysosomal acidification.
Zhu L, Xia X, Li G, Zhu C, Li Q, Wang B, Shi NX, Lei Z, Yang S, Zhang Z, Li H, Tan J, Liu Z, Wen Q, Zhong H, Lin XJ, Sun G, Bao X, Wang Q, Deng L, Bin L, Cao G, Yin Z
Cell reports 2023 Aug 29;42(8):112910
Cell reports 2023 Aug 29;42(8):112910
Sox10 escalates vascular inflammation by mediating vascular smooth muscle cell transdifferentiation and pyroptosis in neointimal hyperplasia.
Xu X, Zhang DD, Kong P, Gao YK, Huang XF, Song Y, Zhang WD, Guo RJ, Li CL, Chen BW, Sun Y, Zhao YB, Jia FY, Wang X, Zhang F, Han M
Cell reports 2023 Aug 29;42(8):112869
Cell reports 2023 Aug 29;42(8):112869
A p53/LINC00324 positive feedback loop suppresses tumor growth by counteracting SET-mediated transcriptional repression.
Zhang L, Zhang J, Xuan X, Wu D, Yu J, Wang P, Yang X, Zhang J, Gan W, He M, Liu XM, Zhou J, Wang D, Gu W, Li D
Cell reports 2023 Aug 29;42(8):112833
Cell reports 2023 Aug 29;42(8):112833
The non-redundant functions of PIWI family proteins in gametogenesis in golden hamsters.
Lv X, Xiao W, Lai Y, Zhang Z, Zhang H, Qiu C, Hou L, Chen Q, Wang D, Gao Y, Song Y, Shui X, Chen Q, Qin R, Liang S, Zeng W, Shi A, Li J, Wu L
Nature communications 2023 Aug 29;14(1):5267
Nature communications 2023 Aug 29;14(1):5267
Inhibition of cancer-type amino acid transporter LAT1 suppresses B16-F10 melanoma metastasis in mouse models.
Shi Z, Kaneda-Nakashima K, Ohgaki R, Xu M, Okanishi H, Endou H, Nagamori S, Kanai Y
Scientific reports 2023 Aug 25;13(1):13943
Scientific reports 2023 Aug 25;13(1):13943
A Compared Study of Eicosapentaenoic Acid and Docosahexaenoic Acid in Improving Seizure-Induced Cognitive Deficiency in a Pentylenetetrazol-Kindling Young Mice Model.
Yang Y, Wang X, Chen L, Wang S, Han J, Wang Z, Wen M
Marine drugs 2023 Aug 24;21(9)
Marine drugs 2023 Aug 24;21(9)
Convergent activation of Ca(2+) permeability in two-pore channel 2 through distinct molecular routes.
Saito R, Mu Q, Yuan Y, Rubio-Alarcón M, Eznarriaga M, Zhao P, Gunaratne G, Kumar S, Keller M, Bracher F, Grimm C, Brailoiu E, Marchant JS, Rahman T, Patel S
Science signaling 2023 Aug 22;16(799):eadg0661
Science signaling 2023 Aug 22;16(799):eadg0661
Flt3 Activation Mitigates Mitochondrial Fragmentation and Heart Dysfunction through Rebalanced L-OPA1 Processing by Hindering the Interaction between Acetylated p53 and PHB2 in Cardiac Remodeling.
Zhang K, Zheng Y, Bao G, Ma W, Han B, Shi H, Zhao Z
Antioxidants (Basel, Switzerland) 2023 Aug 22;12(9)
Antioxidants (Basel, Switzerland) 2023 Aug 22;12(9)
DpdtpA, A Multi-metal Ion Chelator, Attenuates Tau Phosphorylation and Microglial Inflammatory Response via Regulating the PI3K/AKT/GSK-3β Signal Pathways.
Wang L, Wei Y, Sun Z, Jiang LH, Yin Y, Zheng P, Fu Y, Wang H, Li C, Wang JZ
Neuroscience 2023 Aug 21;526:196-203
Neuroscience 2023 Aug 21;526:196-203
Differential effects of PGAM5 knockout on high fat high fructose diet and methionine choline-deficient diet induced non-alcoholic steatohepatitis (NASH) in mice.
Li L, Guo C, Yu Y, Tie L, Lu G, Liu F, Han X, Ji L, Zou X
Cell & bioscience 2023 Aug 21;13(1):154
Cell & bioscience 2023 Aug 21;13(1):154
[VDAC1 participates in house dust mite-induced asthmatic airway inflammation in mice by inducing ferroptosis of airway epithelial cells].
Huang Y, Lin L, Huang H, Dong H
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Aug 20;43(8):1333-1338
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Aug 20;43(8):1333-1338
Inosine enhances tumor mitochondrial respiration by inducing Rag GTPases and nascent protein synthesis under nutrient starvation.
Li MX, Wu XT, Jing WQ, Hou WK, Hu S, Yan W
Cell death & disease 2023 Aug 2;14(8):492
Cell death & disease 2023 Aug 2;14(8):492
Mutational burden of XPNPEP3 leads to defects in mitochondrial complex I and cilia in NPHPL1.
Tong L, Rao J, Yang C, Xu J, Lu Y, Zhang Y, Cang X, Xie S, Mao J, Jiang P
iScience 2023 Aug 18;26(8):107446
iScience 2023 Aug 18;26(8):107446
IRP1 mediated ferroptosis reverses temozolomide resistance in glioblastoma via affecting LCN2/FPN1 signaling axis depended on NFKB2.
Lan Y, Yang T, Yue Q, Wang Z, Zhong X, Luo X, Zuo B, Zhang M, Zeng T, Liu B, Guo H
iScience 2023 Aug 18;26(8):107377
iScience 2023 Aug 18;26(8):107377
A defective mechanosensing pathway affects fibroblast-to-myofibroblast transition in the old male mouse heart.
Angelini A, Trial J, Saltzman AB, Malovannaya A, Cieslik KA
iScience 2023 Aug 18;26(8):107283
iScience 2023 Aug 18;26(8):107283
Warburg effect enhanced by AKR1B10 promotes acquired resistance to pemetrexed in lung cancer-derived brain metastasis.
Duan W, Liu W, Xia S, Zhou Y, Tang M, Xu M, Lin M, Li X, Wang Q
Journal of translational medicine 2023 Aug 16;21(1):547
Journal of translational medicine 2023 Aug 16;21(1):547
Design and discovery of new selective and potent VEGF receptor 2 tyrosine kinase inhibitors.
Hou F, Yao Y, Wei Y, Wang Y, Cao Y, Liu X, Zheng L, Zhang Q, Jiao Y, Chen Y, Meng Y, Sun Y, Wu Y, Wang J, Wang J, Wu Z, Zhang K, Wei M, Yang G
Bioorganic & medicinal chemistry 2023 Aug 15;91:117404
Bioorganic & medicinal chemistry 2023 Aug 15;91:117404
PGAM5 deacetylation mediated by SIRT2 facilitates lipid metabolism and liver cancer proliferation.
Fu G, Li ST, Jiang Z, Mao Q, Xiong N, Li X, Hao Y, Zhang H
Acta biochimica et biophysica Sinica 2023 Aug 15;55(9):1370-1379
Acta biochimica et biophysica Sinica 2023 Aug 15;55(9):1370-1379
FAAP100 is required for the resolution of transcription-replication conflicts in primordial germ cells.
Xu W, Yang Y, Yu Y, Wen C, Zhao S, Cao L, Zhao S, Qin Y, Chen ZJ
BMC biology 2023 Aug 15;21(1):174
BMC biology 2023 Aug 15;21(1):174
Estradiol mitigates stress-induced cardiac injury and inflammation by downregulating ADAM17 via the GPER-1/PI3K signaling pathway.
Adu-Amankwaah J, Bushi A, Tan R, Adekunle AO, Adzika GK, Ndzie Noah ML, Nadeem I, Adzraku SY, Koda S, Mprah R, Cui J, Li K, Wowui PI, Sun H
Cellular and molecular life sciences : CMLS 2023 Aug 12;80(9):246
Cellular and molecular life sciences : CMLS 2023 Aug 12;80(9):246
Structural and biochemical insights into the molecular mechanism of TRPT1 for nucleic acid ADP-ribosylation.
Yang X, Wang J, Li S, Li X, Gong J, Yan Z, Zhou H, Wu C, Liu X
Nucleic acids research 2023 Aug 11;51(14):7649-7665
Nucleic acids research 2023 Aug 11;51(14):7649-7665
Intermittent fasting activates macrophage migration inhibitory factor and alleviates high-fat diet-induced nonalcoholic fatty liver disease.
Li D, Dun Y, Qi D, Ripley-Gonzalez JW, Dong J, Zhou N, Qiu L, Zhang J, Zeng T, You B, Liu S
Scientific reports 2023 Aug 11;13(1):13068
Scientific reports 2023 Aug 11;13(1):13068
Simiao San alleviates hyperuricemia and kidney inflammation by inhibiting NLRP3 inflammasome and JAK2/STAT3 signaling in hyperuricemia mice.
Zhang Y, Wang S, Dai X, Liu T, Liu Y, Shi H, Yin J, Xu T, Zhang Y, Zhao D, Sukhorukov V, Orekhov AN, Gao S, Wang L, Zhang D
Journal of ethnopharmacology 2023 Aug 10;312:116530
Journal of ethnopharmacology 2023 Aug 10;312:116530
Marein reduces lipid levels via modulating the PI3K/AKT/mTOR pathway to induce lipophagy.
Zhang PP, Zhuo BY, Duan ZW, Li X, Huang SL, Cao Q, Zhao T, Wei SL, Hu XH, Zhang Y
Journal of ethnopharmacology 2023 Aug 10;312:116523
Journal of ethnopharmacology 2023 Aug 10;312:116523
Nicotinamide Riboside Improves Stemness of Human Adipose-Derived Stem Cells and Inhibits Terminal Adipocyte Differentiation.
Chinnapaka S, Malekzadeh H, Tirmizi Z, Arellano JA, Ejaz A
Pharmaceuticals (Basel, Switzerland) 2023 Aug 10;16(8)
Pharmaceuticals (Basel, Switzerland) 2023 Aug 10;16(8)
Subchronic Arsenite Exposure Induced Atrophy and Erythropoietin Sensitivity Reduction in Skeletal Muscle Were Relevant to Declined Serum Melatonin Levels in Middle-Aged Rats.
Chen X, Chen W, Wang D, Ma L, Tao J, Zhang A
Toxics 2023 Aug 10;11(8)
Toxics 2023 Aug 10;11(8)
Repetitive Transcranial Magnetic Stimulation Improves Depression-like Behavior in Rats by Promoting Neural Stem Cell Proliferation and Differentiation.
Jiang C, Zheng S, Chen T, Li W, Zhang C, Gu S, Ren H, Huanhuan, Song J, Zhang Z
Neuroscience 2023 Aug 1;524:1-10
Neuroscience 2023 Aug 1;524:1-10
Schisandrin B induces HepG2 cells pyroptosis by activating NK cells mediated anti-tumor immunity.
Song A, Ding T, Wei N, Yang J, Ma M, Zheng S, Jin H
Toxicology and applied pharmacology 2023 Aug 1;472:116574
Toxicology and applied pharmacology 2023 Aug 1;472:116574
Low-dose graphene oxide promotes tumor cells proliferation by activating PI3K-AKT-mTOR signaling via cellular membrane protein integrin αV.
Zheng Z, Halifu A, Ma J, Liu L, Fu Q, Yi B, Du E, Tian D, Xu Y, Zhang Z, Zhu J
Environmental pollution (Barking, Essex : 1987) 2023 Aug 1;330:121817
Environmental pollution (Barking, Essex : 1987) 2023 Aug 1;330:121817
Mucin2 regulated by Ho1/p38/IL-10 axis plays a protective role in polystyrene nanoplastics-mediated intestinal toxicity.
Cui M, He Q, Wang Z, Yu Y, Gao H, Liu Z, Peng H, Wang H, Zhang X, Li D, Chen L, Xing X, Xiao Y, Chen W, Wang Q
Environmental pollution (Barking, Essex : 1987) 2023 Aug 1;330:121808
Environmental pollution (Barking, Essex : 1987) 2023 Aug 1;330:121808
miR-342-5p promotes vascular smooth muscle cell phenotypic transition through a negative-feedback regulation of Notch signaling via targeting FOXO3.
Wen T, Duan Y, Gao D, Zhang X, Zhang X, Liang L, Yang Z, Zhang P, Zhang J, Sun J, Feng Y, Zheng Q, Han H, Yan X
Life sciences 2023 Aug 1;326:121828
Life sciences 2023 Aug 1;326:121828
Repairing gastric ulcer with hyaluronic acid/extracellular matrix composite through promoting M2-type polarization of macrophages.
Ni R, Luo Y, Jiang L, Mao X, Feng Y, Tuersun S, Hu Z, Zhu Y
International journal of biological macromolecules 2023 Aug 1;245:125556
International journal of biological macromolecules 2023 Aug 1;245:125556
A terrified-sound stress causes cognitive impairment in female mice by impairing neuronal plasticity.
Gao S, Zhang L, Wang X, Li R, Han L, Xiong X, Jiang Q, Cheng D, Xiao X, Li H, Yang J
Brain research 2023 Aug 1;1812:148419
Brain research 2023 Aug 1;1812:148419
PARP16-Mediated Stabilization of Amyloid Precursor Protein mRNA Exacerbates Alzheimer's Disease Pathogenesis.
Wang J, Cheng Q, Zhang Y, Hong C, Liu J, Liu X, Chang J
Aging and disease 2023 Aug 1;14(4):1458-1471
Aging and disease 2023 Aug 1;14(4):1458-1471
Houpo paiqi mixture promotes intestinal motility in constipated rats by modulating gut microbiota and activating 5-HT-cAMP-PKA signal pathway.
Wang R, Lu X, Zhao L, Zhang W, Zhang S
Journal of applied microbiology 2023 Aug 1;134(8)
Journal of applied microbiology 2023 Aug 1;134(8)
Weizmannia coagulans JA845 improves atherosclerosis induced by vitamin D3 and high-fat diet in rats through modulating lipid metabolism, oxidative stress, and endothelial vascular injury.
Ma L, Zhao Z, Zhao Y, Gao Y, Zhao L, Li S
Journal of applied microbiology 2023 Aug 1;134(8)
Journal of applied microbiology 2023 Aug 1;134(8)
The effect of PINK1/Parkin pathway on glucose homeostasis imbalance induced by tacrolimus in mouse livers.
Li Z, Xiang J, Mei S, Wu Y, Xu Y
Heliyon 2023 Apr;9(4):e15536
Heliyon 2023 Apr;9(4):e15536
Mitochondrial division inhibitor (mdivi-1) inhibits proliferation and epithelial-mesenchymal transition via the NF-κB pathway in thyroid cancer cells.
Zhang L, Sun L, Wang L, Wang J, Wang D, Jiang J, Zhang J, Zhou Q
Toxicology in vitro : an international journal published in association with BIBRA 2023 Apr;88:105552
Toxicology in vitro : an international journal published in association with BIBRA 2023 Apr;88:105552
Therapeutic role of Artemether in the prevention of hepatic steatosis through miR-34a-5p/PPARα pathway.
Chen L, Yu S, Hong S, Lin X, Zhu X, Cao X, Li Y, Xiao H
Drug development research 2023 Apr;84(2):156-171
Drug development research 2023 Apr;84(2):156-171
Amnion-derived serum amyloid A1 participates in sterile inflammation of fetal membranes at parturition.
Lin YK, Zhang F, Lei WJ, Gan XW, Li MD, Pan F, Wang WS, Sun K
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Apr;72(4):797-812
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Apr;72(4):797-812
Osmoadaptive GLP-1R signalling in hypothalamic neurones inhibits antidiuretic hormone synthesis and release.
Greenwood MP, Greenwood M, Bárez-López S, Hawkins JW, Short K, Tatovic D, Murphy D
Molecular metabolism 2023 Apr;70:101692
Molecular metabolism 2023 Apr;70:101692
Holothuria leucospilota Polysaccharides Improve Immunity and the Gut Microbiota in Cyclophosphamide-Treated Immunosuppressed Mice.
Zhao F, Ma T, Zhang X, Zhao Q, Zhu K, Cao J, Liu Z, Shen X, Li C
Molecular nutrition & food research 2023 Apr;67(8):e2200317
Molecular nutrition & food research 2023 Apr;67(8):e2200317
LncRNA CFAR promotes cardiac fibrosis via the miR-449a-5p/LOXL3/mTOR axis.
Zhang M, Zhang B, Wang X, Song J, Tong M, Dong Z, Xu J, Liu M, Jiang Y, Wang N, Wang Y, Du Z, Liu Y, Zhang R, Xu C
Science China. Life sciences 2023 Apr;66(4):783-799
Science China. Life sciences 2023 Apr;66(4):783-799
SNORD60 promotes the tumorigenesis and progression of endometrial cancer through binding PIK3CA and regulating PI3K/AKT/mTOR signaling pathway.
Wu W, Chen X, Liu X, Bao HJ, Li QH, Xian JY, Lu BF, Zhao Y, Chen S
Molecular carcinogenesis 2023 Apr;62(4):413-426
Molecular carcinogenesis 2023 Apr;62(4):413-426
FUT2-dependent fucosylation of HYOU1 protects intestinal stem cells against inflammatory injury by regulating unfolded protein response.
Wang Z, Tan C, Duan C, Wu J, Zhou D, Hou L, Qian W, Han C, Hou X
Redox biology 2023 Apr;60:102618
Redox biology 2023 Apr;60:102618
Sensitive and quantitative in vivo analysis of PD-L1 using magnetic particle imaging and imaging-guided immunotherapy.
Peng Z, Lu C, Shi G, Yin L, Liang X, Song G, Tian J, Du Y
European journal of nuclear medicine and molecular imaging 2023 Apr;50(5):1291-1305
European journal of nuclear medicine and molecular imaging 2023 Apr;50(5):1291-1305
PGAM4 silencing inhibited glycolysis and chemoresistance to temozolomide in glioma cells.
Lu B, Nie XH, Yin R, Ding P, Su ZZ, Qiu S, Qian YF
Cell biology international 2023 Apr;47(4):776-786
Cell biology international 2023 Apr;47(4):776-786
Hederagenin Suppresses Inflammation and Cartilage Degradation to Ameliorate the Progression of Osteoarthritis: An In vivo and In vitro Study.
Shen Y, Teng L, Qu Y, Huang Y, Peng Y, Tang M, Fu Q
Inflammation 2023 Apr;46(2):655-678
Inflammation 2023 Apr;46(2):655-678
Reciprocal FGF19-GLI2 signaling induces epithelial-to-mesenchymal transition to promote lung squamous cell carcinoma metastasis.
Zhang Y, Wu T, Wang Y, Chen Z, Chen J, Lu S, Xia W
Cellular oncology (Dordrecht, Netherlands) 2023 Apr;46(2):437-450
Cellular oncology (Dordrecht, Netherlands) 2023 Apr;46(2):437-450
Activation of TRPV1 receptor facilitates myelin repair following demyelination via the regulation of microglial function.
Sun JX, Zhu KY, Wang YM, Wang DJ, Zhang MZ, Sarlus H, Benito-Cuesta I, Zhao XQ, Zou ZF, Zhong QY, Feng Y, Wu S, Wang YQ, Harris RA, Wang J
Acta pharmacologica Sinica 2023 Apr;44(4):766-779
Acta pharmacologica Sinica 2023 Apr;44(4):766-779
NONO regulates B-cell development and B-cell receptor signaling.
Zhang Y, Cui D, Huang M, Zheng Y, Zheng B, Chen L, Chen Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Apr;37(4):e22862
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Apr;37(4):e22862
P4HA2-mediated HIF-1α stabilization promotes erdafitinib-resistance in FGFR3-alteration bladder cancer.
Li X, Li Y, Liu B, Chen L, Lyu F, Zhang P, He Q, Cheng L, Liu C, Song Y, Xing Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Apr;37(4):e22840
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Apr;37(4):e22840
Perilla frutescens L. alleviates trimethylamine N-oxide-induced apoptosis in the renal tubule by regulating ASK1-JNK phosphorylation.
Yong C, Huang G, Ge H, Zhu Y, Yang Y, Yu Y, Tian F, Gao K, Zhou E
Phytotherapy research : PTR 2023 Apr;37(4):1274-1292
Phytotherapy research : PTR 2023 Apr;37(4):1274-1292
Reshaping the Endogenous Electric Field to Boost Wound Repair via Electrogenerative Dressing.
Luo R, Liang Y, Yang J, Feng H, Chen Y, Jiang X, Zhang Z, Liu J, Bai Y, Xue J, Chao S, Xi Y, Liu X, Wang E, Luo D, Li Z, Zhang J
Advanced materials (Deerfield Beach, Fla.) 2023 Apr;35(16):e2208395
Advanced materials (Deerfield Beach, Fla.) 2023 Apr;35(16):e2208395
Influence of cyclin D1 splicing variants expression on breast cancer chemoresistance via CDK4/CyclinD1-pRB-E2F1 pathway.
Wang J, Zhang J, Ma Q, Zhang S, Ma F, Su W, Zhang T, Xie X, Di C
Journal of cellular and molecular medicine 2023 Apr;27(7):991-1005
Journal of cellular and molecular medicine 2023 Apr;27(7):991-1005
Kaempferol promotes melanogenesis and reduces oxidative stress in PIG1 normal human skin melanocytes.
Xie Y, Mei X, Shi W
Journal of cellular and molecular medicine 2023 Apr;27(7):982-990
Journal of cellular and molecular medicine 2023 Apr;27(7):982-990
Tax1 binding protein 3 regulates osteogenic and adipogenic differentiation through inactivating Wnt/β-catenin signalling.
Wang Y, Gan Y, Dong Y, Zhou J, Zhu E, Yuan H, Li X, Wang B
Journal of cellular and molecular medicine 2023 Apr;27(7):950-961
Journal of cellular and molecular medicine 2023 Apr;27(7):950-961
Knockdown of the long non‑coding RNA MALAT1 ameliorates TNF‑α‑mediated endothelial cell pyroptosis via the miR‑30c‑5p/Cx43 axis.
Yang ZJ, Liu R, Han XJ, Qiu CL, Dong GL, Liu ZQ, Liu LH, Luo Y, Jiang LP
Molecular medicine reports 2023 Apr;27(4)
Molecular medicine reports 2023 Apr;27(4)
Hydroxysafflor Yellow A Exerts Neuroprotective Effect by Reducing Aβ Toxicity Through Inhibiting Endoplasmic Reticulum Stress in Oxygen-Glucose Deprivation/Reperfusion Cell Model.
Ma HH, Wen JR, Fang H, Su S, Wan C, Zhang C, Lu FM, Fan LL, Wu GL, Zhou ZY, Qiao LJ, Zhang SJ, Cai YF
Rejuvenation research 2023 Apr;26(2):57-67
Rejuvenation research 2023 Apr;26(2):57-67
LPS inhibits TRIM65 expression in macrophages and C57BL/6J mouse by activating the ERK1/2 signaling pathway.
Zeng X, Deng X, Ni Y, Bi H, Jiang M, Wang D, Dong P, Xiao Y, Jiang M
Experimental and therapeutic medicine 2023 Apr;25(4):188
Experimental and therapeutic medicine 2023 Apr;25(4):188
Low expression of SEMA4D as a potential predictive molecular marker of poor survival in patients with melanoma combined with liver cancer.
Liu X, Zhang C, Yang WH, Li SC, Wang RF, Zhang YB, Zhang ZL
Oncology letters 2023 Apr;25(4):160
Oncology letters 2023 Apr;25(4):160
PSKH1 affects proliferation and invasion of osteosarcoma cells via the p38/MAPK signaling pathway.
Zhu X, Jiang C, Wang Z, Zhu X, Yuan F, Yang Y
Oncology letters 2023 Apr;25(4):144
Oncology letters 2023 Apr;25(4):144
MiR-133a/CD47 axis is a novel prognostic biomarker to promote triple negative breast cancer progression.
Yan H, Huang W, Chen C, Zhang X, Zhu K, Yuan J
Pathology, research and practice 2023 Apr;244:154400
Pathology, research and practice 2023 Apr;244:154400
CircHGS enhances the progression of bladder cancer by regulating the miR-513a-5p/VEGFC axis and activating the AKT/mTOR signaling pathway.
Zhu Y, Zuo L, Xiong H, Li S, Chen R, Liu H
Cell cycle (Georgetown, Tex.) 2023 Apr;22(8):919-938
Cell cycle (Georgetown, Tex.) 2023 Apr;22(8):919-938
Dimethyl fumarate protects against hepatic ischemia-reperfusion injury by alleviating ferroptosis via the NRF2/SLC7A11/HO-1 axis.
Qi D, Chen P, Bao H, Zhang L, Sun K, Song S, Li T
Cell cycle (Georgetown, Tex.) 2023 Apr;22(7):818-828
Cell cycle (Georgetown, Tex.) 2023 Apr;22(7):818-828
ADAMTS12 promotes migration and epithelial-mesenchymal transition and predicts poor prognosis for pancreatic cancer.
He RZ, Zheng JH, Yao HF, Xu DP, Yang MW, Liu DJ, Sun YW, Huo YM
Hepatobiliary & pancreatic diseases international : HBPD INT 2023 Apr;22(2):169-178
Hepatobiliary & pancreatic diseases international : HBPD INT 2023 Apr;22(2):169-178
Lenvatinib inhibited HCC cell migration and invasion through regulating the transcription and ubiquitination of UHRF1 and DNMT1.
Fang T, Jiao Z, You Y, Cao J, Wang C, Liu J, Zhao W
Biochemical pharmacology 2023 Apr;210:115489
Biochemical pharmacology 2023 Apr;210:115489
Oncogenic FLT3 internal tandem duplication activates E2F1 to regulate purine metabolism in acute myeloid leukaemia.
Ou ZY, Wang K, Shen WW, Deng G, Xu YY, Wang LF, Zai ZY, Ling YA, Zhang T, Peng XQ, Chen FH
Biochemical pharmacology 2023 Apr;210:115458
Biochemical pharmacology 2023 Apr;210:115458
Selenoprotein Gene mRNA Expression Evaluation During Renal Ischemia-Reperfusion Injury in Rats and Ebselen Intervention Effects.
Wu Y, Shi H, Xu Y, Wen R, Gong M, Hong G, Xu S
Biological trace element research 2023 Apr;201(4):1792-1805
Biological trace element research 2023 Apr;201(4):1792-1805
HTR2A agonists play a therapeutic role by restricting ILC2 activation in papain-induced lung inflammation.
Wang Z, Yan C, Du Q, Huang Y, Li X, Zeng D, Mao R, Gurram RK, Cheng S, Gu W, Zhu L, Fan W, Ma L, Ling Z, Qiu J, Li D, Liu E, Zhang Y, Fang Y, Zhu J, Sun B
Cellular & molecular immunology 2023 Apr;20(4):404-418
Cellular & molecular immunology 2023 Apr;20(4):404-418
Selenoprotein K enhances STING oligomerization to facilitate antiviral response.
Lv L, Chai L, Wang J, Wang M, Qin D, Song H, Fu Y, Zhao C, Jia J, Zhao W, Jia M
PLoS pathogens 2023 Apr;19(4):e1011314
PLoS pathogens 2023 Apr;19(4):e1011314
FOXP3+ macrophage represses acute ischemic stroke-induced neural inflammation.
Cai W, Hu M, Li C, Wu R, Lu D, Xie C, Zhang W, Li T, Shen S, Huang H, Qiu W, Liu Q, Lu Y, Lu Z
Autophagy 2023 Apr;19(4):1144-1163
Autophagy 2023 Apr;19(4):1144-1163
Necroptosis plays a crucial role in the exacerbation of retinal injury after blunt ocular trauma.
Huan Y, Wu XQ, Chen T, Dou YN, Jia B, He X, Wei DY, Fei Z, Fei F
Neural regeneration research 2023 Apr;18(4):922-928
Neural regeneration research 2023 Apr;18(4):922-928
Identification and functional analysis of three novel genetic variants resulting in premature termination codons in three unrelated patients with hereditary antithrombin deficiency.
Imai Y, Nagaya S, Araiso Y, Meguro-Horike M, Togashi T, Ohmori K, Makita Y, Sato E, Yujiri T, Nagamori Y, Horike SI, Watanabe A, Morishita E
International journal of hematology 2023 Apr;117(4):523-529
International journal of hematology 2023 Apr;117(4):523-529
EGFR-TNFR1 pathway in endothelial cell facilitates acute lung injury by NF-κB/MAPK-mediated inflammation and RIP3-dependent necroptosis.
Zhang H, Zhang X, Ling C, Liu C, Hua S, Xiong Z, Zhao H, Feng Q, Feng Z, Tang J, Hong X
International immunopharmacology 2023 Apr;117:109902
International immunopharmacology 2023 Apr;117:109902
ARID1B blocks methionine-stimulated mTOR activation to inhibit milk fat and protein synthesis in and proliferation of mouse mammary epithelial cells.
Lin G, Qi H, Guo X, Wang W, Zhang M, Gao X
The Journal of nutritional biochemistry 2023 Apr;114:109274
The Journal of nutritional biochemistry 2023 Apr;114:109274
Acinetobacter baumannii outer membrane protein A induces autophagy in bone marrow-derived dendritic cells involving the PI3K/mTOR pathway.
Tan H, Cao L
Immunity, inflammation and disease 2023 Apr;11(4):e830
Immunity, inflammation and disease 2023 Apr;11(4):e830
Engineered Extracellular Vesicle-Delivered CRISPR/CasRx as a Novel RNA Editing Tool.
Li T, Zhang L, Lu T, Zhu T, Feng C, Gao N, Liu F, Yu J, Chen K, Zhong J, Tang Q, Zhang Q, Deng X, Ren J, Zeng J, Zhou H, Zhu J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Apr;10(10):e2206517
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Apr;10(10):e2206517
Wei-Tong-Xin exerts anti-inflammatory effects through TLR4-mediated macrophages M1/M2 polarization and affects GLP-1 secretion.
Zhang X, Yang X, Zhang S, Wang J, Wang M, Ma T, Wan M, Lv X, Yan T, Jia Y
The Journal of pharmacy and pharmacology 2023 Apr 7;75(4):574-584
The Journal of pharmacy and pharmacology 2023 Apr 7;75(4):574-584
ZSWIM1 Promotes the Proliferation and Metastasis of Lung Adenocarcinoma Cells through the STK38/MEKK2/ERK1/2 Axis.
Gao X, Lian Q, Guan B, Liu QY, Meng M, Chen Y, Jin J, Li H, Liu X, Sun Z, Liu L, He QY, Zhang G
Journal of proteome research 2023 Apr 7;22(4):1080-1091
Journal of proteome research 2023 Apr 7;22(4):1080-1091
Integrated network pharmacology and experimental verification to explore the molecular mechanism of Jingxin Zhidong formula for treating Tic disorder.
Tian X, Ou G, Hu S, Wang C, Han F, Gao L
Journal of ethnopharmacology 2023 Apr 6;305:116114
Journal of ethnopharmacology 2023 Apr 6;305:116114
Identification of hub genes and pathways in lung metastatic colorectal cancer.
Dai W, Guo C, Wang Y, Li Y, Xie R, Wu J, Yao B, Xie D, He L, Li Y, Huang H, Wang Y, Liu S
BMC cancer 2023 Apr 6;23(1):323
BMC cancer 2023 Apr 6;23(1):323
RNF20 is required for male fertility through regulation of H2B ubiquitination in the Sertoli cells.
Lai F, Wang H, Zhao X, Yang K, Cai L, Hu M, Lin L, Xia X, Li W, Cheng H, Zhou R
Cell & bioscience 2023 Apr 6;13(1):71
Cell & bioscience 2023 Apr 6;13(1):71
Goliath induces inflammation in obese mice by linking fatty acid β-oxidation to glycolysis.
Hao S, Zhang S, Ye J, Chen L, Wang Y, Pei S, Zhu Q, Xu J, Tao Y, Zhou N, Yin H, Duan CW, Mao C, Zheng M, Xiao Y
EMBO reports 2023 Apr 5;24(4):e56932
EMBO reports 2023 Apr 5;24(4):e56932
Ligation to Scavenging Strategy Enables On-Demand Termination of Targeted Protein Degradation.
Jin Y, Fan J, Wang R, Wang X, Li N, You Q, Jiang Z
Journal of the American Chemical Society 2023 Apr 5;145(13):7218-7229
Journal of the American Chemical Society 2023 Apr 5;145(13):7218-7229
Lateral septum adenosine A(2A) receptors control stress-induced depressive-like behaviors via signaling to the hypothalamus and habenula.
Wang M, Li P, Li Z, da Silva BS, Zheng W, Xiang Z, He Y, Xu T, Cordeiro C, Deng L, Dai Y, Ye M, Lin Z, Zhou J, Zhou X, Ye F, Cunha RA, Chen J, Guo W
Nature communications 2023 Apr 5;14(1):1880
Nature communications 2023 Apr 5;14(1):1880
Characterization of dominant-negative growth hormone receptor variants reveals a potential therapeutic target for short stature.
Andrews A, Cottrell E, Maharaj A, Ladha T, Williams J, Schilbach K, Kaisinger LR, Perry JRB, Metherell LA, McCormick PJ, Storr HL
European journal of endocrinology 2023 Apr 4;188(4):353-365
European journal of endocrinology 2023 Apr 4;188(4):353-365
Heat-Killed Lacticaseibacillus paracasei Repairs Lipopolysaccharide-Induced Intestinal Epithelial Barrier Damage via MLCK/MLC Pathway Activation.
Xie Z, Zhang G, Liu R, Wang Y, Tsapieva AN, Zhang L, Han J
Nutrients 2023 Apr 4;15(7)
Nutrients 2023 Apr 4;15(7)
Aqueous-soluble components of sporoderm-removed Ganoderma lucidum spore powder promote ferroptosis in oral squamous cell carcinoma.
Wu X, Wu Q, Wang Y, Liu Y, Li Z, Liu Q, Huang Z, Li M, Zhang B, Zhan Q
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2023 Apr 30;35(2):176-190
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2023 Apr 30;35(2):176-190
Donkey Oil-Based Ketogenic Diet Prevents Tumor Progression by Regulating Intratumor Inflammation, Metastasis and Angiogenesis in CT26 Tumor-Bearing Mice.
Zhang H, Xie L, Zhang N, Qi X, Lu T, Xing J, Akhtar MF, Li L, Liu G
Genes 2023 Apr 30;14(5)
Genes 2023 Apr 30;14(5)
The outer mitochondrial membrane protein TMEM11 demarcates spatially restricted BNIP3/BNIP3L-mediated mitophagy.
Gok MO, Connor OM, Wang X, Menezes CJ, Llamas CB, Mishra P, Friedman JR
The Journal of cell biology 2023 Apr 3;222(4)
The Journal of cell biology 2023 Apr 3;222(4)
Knockdown of the SELENOK gene induces ferroptosis in cervical cancer cells.
Abdurahman A, Li Y, Jia SZ, Xu XW, Lin SJ, Ouyang P, Jun He Z, Zhang ZH, Liu Q, Xu Y, Song GL
Metallomics : integrated biometal science 2023 Apr 3;15(4)
Metallomics : integrated biometal science 2023 Apr 3;15(4)
Caffeine can alleviate non-alcoholic fatty liver disease by augmenting LDLR expression via targeting EGFR.
Huang YW, Wang LT, Zhang M, Nie Y, Yang JB, Meng WL, Wang XJ, Sheng J
Food & function 2023 Apr 3;14(7):3269-3278
Food & function 2023 Apr 3;14(7):3269-3278
Upregulation of carbonic anhydrase 1 beneficial for depressive disorder.
Cheng K, Wang Y, He Y, Tian Y, Li J, Chen C, Xu X, Wu Z, Yu H, Chen X, Wu Y, Song W, Dong Z, Xu H, Xie P
Acta neuropathologica communications 2023 Apr 3;11(1):59
Acta neuropathologica communications 2023 Apr 3;11(1):59
Identification of glutamyl-prolyl-tRNA synthetase as a new therapeutic target in hepatocellular carcinoma via a novel bioinformatic approach.
Shu J, Luo P, Zhang G, Gao Y
Journal of gastrointestinal oncology 2023 Apr 29;14(2):636-649
Journal of gastrointestinal oncology 2023 Apr 29;14(2):636-649
Dual role of PID1 in regulating apoptosis induced by distinct anticancer-agents through AKT/Raf-1-dependent pathway in hepatocellular carcinoma.
Yang J, Li S, He J, Xu Q, Xie M, Yang C, Wang H, Zhang Y, Wan Q, Xiang M
Cell death discovery 2023 Apr 28;9(1):139
Cell death discovery 2023 Apr 28;9(1):139
N(6)-methyladenosine reader IGF2BP3 as a prognostic Biomarker contribute to malignant progression of glioma.
Zheng X, Li S, Yu J, Dai C, Yan S, Chen G, Sun C
Translational cancer research 2023 Apr 28;12(4):992-1005
Translational cancer research 2023 Apr 28;12(4):992-1005
Acinous cell AR42J-derived exosome miR125b-5p promotes acute pancreatitis exacerbation by inhibiting M2 macrophage polarization via PI3K/AKT signaling pathway.
Zheng Z, Cao F, Ding YX, Lu JD, Fu YQ, Liu L, Guo YL, Liu S, Sun HC, Cui YQ, Li F
World journal of gastrointestinal surgery 2023 Apr 27;15(4):600-620
World journal of gastrointestinal surgery 2023 Apr 27;15(4):600-620
MAVS-Based Reporter Systems for Real-Time Imaging of EV71 Infection and Antiviral Testing.
Li X, Yang E, Li X, Fan T, Guo S, Yang H, Wu B, Wang H
Viruses 2023 Apr 26;15(5)
Viruses 2023 Apr 26;15(5)
The complement inhibitor CD59 is required for GABAergic synaptic transmission in the dentate gyrus.
Wen L, Yang X, Wu Z, Fu S, Zhan Y, Chen Z, Bi D, Shen Y
Cell reports 2023 Apr 25;42(4):112349
Cell reports 2023 Apr 25;42(4):112349
Synergistic effect of constituent drugs of Baibutang on improving Yin-deficiency pulmonary fibrosis in rats.
Fu S, Song X, Tang X, Qian X, Du Z, Hu Y, Xu X, Zhang M
Journal of ethnopharmacology 2023 Apr 24;306:116050
Journal of ethnopharmacology 2023 Apr 24;306:116050
Progerinin, an Inhibitor of Progerin, Alleviates Cardiac Abnormalities in a Model Mouse of Hutchinson-Gilford Progeria Syndrome.
Kang SM, Seo S, Song EJ, Kweon O, Jo AH, Park S, Woo TG, Kim BH, Oh GT, Park BJ
Cells 2023 Apr 24;12(9)
Cells 2023 Apr 24;12(9)
Sleeve gastrectomy decreased hepatic lipid accumulation by inducing autophagy via AMPK/mTOR pathway.
Zeng R, Zeng Y, Wang Q, Li X, Liu J, Li B, Zhang G, Hu S
Biochemical and biophysical research communications 2023 Apr 23;653:115-125
Biochemical and biophysical research communications 2023 Apr 23;653:115-125
In situ isolation of nuclei or nuclear proteins from adherent cells: a simple, effective method with less cytoplasmic contamination.
Qin Y, Zhou Y, Wang K, Gu J, Xiong Z, Zhang W, Chen Y
Biological research 2023 Apr 21;56(1):18
Biological research 2023 Apr 21;56(1):18
Human Cytomegalovirus UL23 Antagonizes the Antiviral Effect of Interferon-γ by Restraining the Expression of Specific IFN-Stimulated Genes.
Wang H, Peng W, Wang J, Zhang C, Zhao W, Ran Y, Yang X, Chen J, Li H
Viruses 2023 Apr 20;15(4)
Viruses 2023 Apr 20;15(4)
Protective Effect of Lonicera japonica on PM(2.5)-Induced Pulmonary Damage in BALB/c Mice via the TGF-β and NF-κB Pathway.
Lee HL, Kim JM, Go MJ, Kim TY, Joo SG, Kim JH, Lee HS, Kim HJ, Heo HJ
Antioxidants (Basel, Switzerland) 2023 Apr 20;12(4)
Antioxidants (Basel, Switzerland) 2023 Apr 20;12(4)
NLRP3 Plays a Key Role in Antihelminth Immunity in the Enteral and Parenteral Stages of Trichinella spiralis-Infected Mice.
Pan TX, Huang HB, Lu HN, Zhao GX, Quan Y, Li JY, Xue Y, Zhu ZY, Wang Y, Shi CW, Wang N, Yang GL, Wang CF
Infection and immunity 2023 Apr 18;91(4):e0038222
Infection and immunity 2023 Apr 18;91(4):e0038222
p53 protects against alcoholic fatty liver disease via ALDH2 inhibition.
Yao P, Zhang Z, Liu H, Jiang P, Li W, Du W
The EMBO journal 2023 Apr 17;42(8):e112304
The EMBO journal 2023 Apr 17;42(8):e112304
Phosphorylation and stabilization of EZH2 by DCAF1/VprBP trigger aberrant gene silencing in colon cancer.
Ghate NB, Kim S, Shin Y, Kim J, Doche M, Valena S, Situ A, Kim S, Rhie SK, Lenz HJ, Ulmer TS, Mumenthaler SM, An W
Nature communications 2023 Apr 17;14(1):2140
Nature communications 2023 Apr 17;14(1):2140
Vimar/RAP1GDS1 promotes acceleration of brain aging after flies and mice reach middle age.
Xiong Y, Cheng Q, Li Y, Han Y, Sun X, Liu L
Communications biology 2023 Apr 15;6(1):420
Communications biology 2023 Apr 15;6(1):420
Mitoglitazone ameliorates renal ischemia/reperfusion injury by inhibiting ferroptosis via targeting mitoNEET.
Qi Y, Hu M, Qiu Y, Zhang L, Yan Y, Feng Y, Feng C, Hou X, Wang Z, Zhang D, Zhao J
Toxicology and applied pharmacology 2023 Apr 15;465:116440
Toxicology and applied pharmacology 2023 Apr 15;465:116440
cGAS Mediates Inflammation by Polarizing Macrophages to M1 Phenotype via the mTORC1 Pathway.
Shen X, Sun C, Cheng Y, Ma D, Sun Y, Lin Y, Zhao Y, Yang M, Jing W, Cui X, Han L
Journal of immunology (Baltimore, Md. : 1950) 2023 Apr 15;210(8):1098-1107
Journal of immunology (Baltimore, Md. : 1950) 2023 Apr 15;210(8):1098-1107
High-cholesterol diet promotes depression- and anxiety-like behaviors in mice by impact gut microbe and neuroinflammation.
Zou L, Tian Y, Wang Y, Chen D, Lu X, Zeng Z, Chen Z, Lin C, Liang Y
Journal of affective disorders 2023 Apr 14;327:425-438
Journal of affective disorders 2023 Apr 14;327:425-438
Resveratrol induces proliferation and differentiation of mouse pre-osteoblast MC3T3-E1 by promoting autophagy.
Cai W, Sun B, Song C, Liu F, Wu Z, Liu Z
BMC complementary medicine and therapies 2023 Apr 14;23(1):121
BMC complementary medicine and therapies 2023 Apr 14;23(1):121
EPC-exosomal miR-26a-5p improves airway remodeling in COPD by inhibiting ferroptosis of bronchial epithelial cells via PTGS2/PGE2 signaling pathway.
Liu C, Lu J, Yuan T, Xie L, Zhang L
Scientific reports 2023 Apr 14;13(1):6126
Scientific reports 2023 Apr 14;13(1):6126
Immunophenotyping of Monocyte Migration Markers and Therapeutic Effects of Selenium on IL-6 and IL-1β Cytokine Axes of Blood Mononuclear Cells in Preoperative and Postoperative Coronary Artery Disease Patients.
Wacker M, Ball A, Beer HD, Schmitz I, Borucki K, Azizzadeh F, Scherner M, Awad G, Wippermann J, Veluswamy P
International journal of molecular sciences 2023 Apr 13;24(8)
International journal of molecular sciences 2023 Apr 13;24(8)
TIGD1 Function as a Potential Cuproptosis Regulator Following a Novel Cuproptosis-Related Gene Risk Signature in Colorectal Cancer.
Wu Z, Lin C, Zhang F, Lu Z, Wang Y, Liu Y, Zhou Z, Li L, Song L
Cancers 2023 Apr 13;15(8)
Cancers 2023 Apr 13;15(8)
Porcine Epidemic Diarrhea Virus Replication in Human Intestinal Cells Reveals Potential Susceptibility to Cross-Species Infection.
Niu Z, Zhang S, Xu S, Wang J, Wang S, Hu X, Zhang L, Ren L, Zhang J, Liu X, Zhou Y, Yang L, Song Z
Viruses 2023 Apr 13;15(4)
Viruses 2023 Apr 13;15(4)
Menstrual blood-derived endometrial stem cells alleviate neuroinflammation by modulating M1/M2 polarization in cell and rat Parkinson's disease models.
Li H, Wei J, Zhang Z, Li J, Ma Y, Zhang P, Lin J
Stem cell research & therapy 2023 Apr 13;14(1):85
Stem cell research & therapy 2023 Apr 13;14(1):85
Excessive serine from the bone marrow microenvironment impairs megakaryopoiesis and thrombopoiesis in Multiple Myeloma.
Kuang C, Xia M, An G, Liu C, Hu C, Zhang J, Liu Z, Meng B, Su P, Xia J, Guo J, Zhu Y, Liu X, Wu X, Shen Y, Feng X, He Y, Li J, Qiu L, Zhou J, Zhou W
Nature communications 2023 Apr 13;14(1):2093
Nature communications 2023 Apr 13;14(1):2093
Xiaoyaosan ameliorates depressive-like behavior and susceptibility to glucose intolerance in rat: involvement of LepR-STAT3/PI3K pathway in hypothalamic arcuate nucleus.
Qiu W, Wu Q, Zhang K, Da X, Tang K, Yuan N, Deng L, Wu M, Zhang Y, Quan J, Ma Q, Li X, Chen J
BMC complementary medicine and therapies 2023 Apr 12;23(1):116
BMC complementary medicine and therapies 2023 Apr 12;23(1):116
Hepatic G Protein-Coupled Receptor 180 Deficiency Ameliorates High Fat Diet-Induced Lipid Accumulation via the Gi-PKA-SREBP Pathway.
Zhang Y, Zhu Z, Sun L, Yin W, Liang Y, Chen H, Bi Y, Zhai W, Yin Y, Zhang W
Nutrients 2023 Apr 11;15(8)
Nutrients 2023 Apr 11;15(8)
Deregulation of ER-mitochondria contact formation and mitochondrial calcium homeostasis mediated by VDAC in fragile X syndrome.
Geng J, Khaket TP, Pan J, Li W, Zhang Y, Ping Y, Cobos Sillero MI, Lu B
Developmental cell 2023 Apr 10;58(7):597-615.e10
Developmental cell 2023 Apr 10;58(7):597-615.e10
Palmitoyl transferases act as novel drug targets for pancreatic cancer.
Lin Z, Lv Z, Liu X, Huang K
Journal of translational medicine 2023 Apr 10;21(1):249
Journal of translational medicine 2023 Apr 10;21(1):249
ME2 Promotes Hepatocellular Carcinoma Cell Migration through Pyruvate.
Yang Y, Zhang Z, Li W, Li L, Zhou Y, Du W
Metabolites 2023 Apr 10;13(4)
Metabolites 2023 Apr 10;13(4)
Exosomal circCLIP1 regulates PM(2.5)-induced airway obstruction via targeting SEPT10 in vitro.
Zhu H, Tang X, Zhang H, Zhou M, Liu H, Chu H, Zhang Z
Ecotoxicology and environmental safety 2023 Apr 1;254:114750
Ecotoxicology and environmental safety 2023 Apr 1;254:114750
Subchronic Microcystin-LR Aggravates Colorectal Inflammatory Response and Barrier Disruption via Raf/ERK Signaling Pathway in Obese Mice.
Yang Y, Zheng S, Chu H, Du C, Chen M, Emran MY, Chen J, Yang F, Tian L
Toxins 2023 Apr 1;15(4)
Toxins 2023 Apr 1;15(4)
Identification of FEZ2 as a potential oncogene in pancreatic ductal adenocarcinoma.
Yang C, Wang X, Qiu C, Zheng Z, Lin K, Tu M, Zhang K, Jiang K, Gao W
PeerJ 2022;9:e12736
PeerJ 2022;9:e12736
Role of TRPV1 ion channel in cervical squamous cell carcinoma genesis.
Wang Z, Dong J, Tian W, Qiao S, Wang H
Frontiers in molecular biosciences 2022;9:980262
Frontiers in molecular biosciences 2022;9:980262
Identification of amino acid residues in the MT-loop of MT1-MMP critical for its ability to cleave low-density lipoprotein receptor.
Wang M, Alabi A, Gu HM, Gill G, Zhang Z, Jarad S, Xia XD, Shen Y, Wang GQ, Zhang DW
Frontiers in cardiovascular medicine 2022;9:917238
Frontiers in cardiovascular medicine 2022;9:917238
Structural Characterization and Anti-breast Cancer Activity in vitro of a Novel Polysaccharide From Cymbopogon citratus.
Chen Y, Qiao S, Liu H, Xing H, Chen P
Frontiers in nutrition 2022;9:911838
Frontiers in nutrition 2022;9:911838
Sodium-glucose cotransporter-2 inhibitor alleviated atrial remodeling in STZ-induced diabetic rats by targeting TLR4 pathway.
Zhan X, Cheng L, Huo N, Yu L, Liu C, Liu T, Li G, Fu H
Frontiers in cardiovascular medicine 2022;9:908037
Frontiers in cardiovascular medicine 2022;9:908037
The Protective Effect of Sulforaphane on Dextran Sulfate Sodium-Induced Colitis Depends on Gut Microbial and Nrf2-Related Mechanism.
He C, Gao M, Zhang X, Lei P, Yang H, Qing Y, Zhang L
Frontiers in nutrition 2022;9:893344
Frontiers in nutrition 2022;9:893344
(-)-Epicatechin Provides Neuroprotection in Sodium Iodate-Induced Retinal Degeneration.
Peng M, Zhou X, Yao F, Li H, Song W, Xiong S, Xia X
Frontiers in medicine 2022;9:879901
Frontiers in medicine 2022;9:879901
Isoliquiritin Ameliorates Cisplatin-Induced Renal Proximal Tubular Cell Injury by Antagonizing Apoptosis, Oxidative Stress and Inflammation.
Pei Z, Wu M, Yu H, Long G, Gui Z, Li X, Chen H, Jia Z, Xia W
Frontiers in medicine 2022;9:873739
Frontiers in medicine 2022;9:873739
Momordica. charantia-Derived Extracellular Vesicles-Like Nanovesicles Protect Cardiomyocytes Against Radiation Injury via Attenuating DNA Damage and Mitochondria Dysfunction.
Cui WW, Ye C, Wang KX, Yang X, Zhu PY, Hu K, Lan T, Huang LY, Wang W, Gu B, Yan C, Ma P, Qi SH, Luo L
Frontiers in cardiovascular medicine 2022;9:864188
Frontiers in cardiovascular medicine 2022;9:864188
Ornithine α-Ketoglutarate Alleviates Inflammation via Regulating Ileal Mucosa Microbiota and Metabolites in Enterotoxigenic Escherichia coli-Infected Pigs.
Li Y, Bao X, Yang F, Tian J, Su W, Yin J, Yao K, Li T, Yin Y
Frontiers in nutrition 2022;9:862498
Frontiers in nutrition 2022;9:862498
The Mechanism of Lipopolysaccharide Escaping the Intestinal Barrier in Megalobrama amblycephala Fed a High-Fat Diet.
Dai YJ, Liu WB, Abasubong KP, Zhang DD, Li XF, Xiao K, Wang X, Jiang GZ
Frontiers in nutrition 2022;9:853409
Frontiers in nutrition 2022;9:853409
Berberine Ameliorates Inflammation in Acute Lung Injury via NF-κB/Nlrp3 Signaling Pathway.
Chen J, Huang Y, Bian X, He Y
Frontiers in nutrition 2022;9:851255
Frontiers in nutrition 2022;9:851255
Effects of Excessive Activation of N-methyl-D-aspartic Acid Receptors in Neonatal Cardiac Mitochondrial Dysfunction Induced by Intrauterine Hypoxia.
Liu Y, Luo Z, Liao Z, Wang M, Zhou Y, Luo S, Ding Y, Liu T, Cao C, Yue S
Frontiers in cardiovascular medicine 2022;9:837142
Frontiers in cardiovascular medicine 2022;9:837142
Metabolomic Profile Reveals That Ceramide Metabolic Disturbance Plays an Important Role in Thoracic Aortic Dissection.
Yang H, Yang F, Luo M, Chen Q, Liu X, Zhang Y, Zhu G, Chen W, Li T, Shu C, Zhou Z
Frontiers in cardiovascular medicine 2022;9:826861
Frontiers in cardiovascular medicine 2022;9:826861
Selective Cleavage at CCA Ends and Anticodon Loops of tRNAs by Stress-Induced RNases.
Akiyama Y, Lyons SM, Fay MM, Tomioka Y, Abe T, Anderson PJ, Ivanov P
Frontiers in molecular biosciences 2022;9:791094
Frontiers in molecular biosciences 2022;9:791094
Expression of the Immune Checkpoint Protein VISTA Is Differentially Regulated by the TGF-β1 - Smad3 Signaling Pathway in Rapidly Proliferating Human Cells and T Lymphocytes.
Schlichtner S, Yasinska IM, Ruggiero S, Berger SM, Aliu N, Prunk M, Kos J, Meyer NH, Gibbs BF, Fasler-Kan E, Sumbayev VV
Frontiers in medicine 2022;9:790995
Frontiers in medicine 2022;9:790995
Melatonin Engineered Adipose-Derived Biomimetic Nanovesicles Regulate Mitochondrial Functions and Promote Myocardial Repair in Myocardial Infarction.
Zhang Y, Yang N, Huang X, Zhu Y, Gao S, Liu Z, Cao F, Wang Y
Frontiers in cardiovascular medicine 2022;9:789203
Frontiers in cardiovascular medicine 2022;9:789203
Dishevelled-Associated Activator of Morphogenesis 2 (DAAM2) Predicts the Immuno-Hot Phenotype in Pancreatic Adenocarcinoma.
Zhang Q, Pan J, Nie H, Wang H, An F, Zhan Q
Frontiers in molecular biosciences 2022;9:750083
Frontiers in molecular biosciences 2022;9:750083
Differential Expression Profile of microRNAs and Tight Junction in the Lung Tissues of Rat With Mitomycin-C-Induced Pulmonary Veno-Occlusive Disease.
Song Q, Chen P, Wu SJ, Chen Y, Zhang Y
Frontiers in cardiovascular medicine 2022;9:746888
Frontiers in cardiovascular medicine 2022;9:746888
Molecular and Cellular Response of the Myocardium (H9C2 Cells) Towards Hypoxia and HIF-1α Inhibition.
Osuru HP, Lavallee M, Thiele RH
Frontiers in cardiovascular medicine 2022;9:711421
Frontiers in cardiovascular medicine 2022;9:711421
Cryptotanshinone attenuates LPS-induced acute lung injury by regulating metabolic reprogramming of macrophage.
Ye Z, Wang P, Feng G, Wang Q, Liu C, Lu J, Chen J, Liu P
Frontiers in medicine 2022;9:1075465
Frontiers in medicine 2022;9:1075465
Exosomes derived from M2 macrophages induce angiogenesis to promote wound healing.
Lyu L, Cai Y, Zhang G, Jing Z, Liang J, Zhang R, Dang X, Zhang C
Frontiers in molecular biosciences 2022;9:1008802
Frontiers in molecular biosciences 2022;9:1008802
Metabolic Reprogramming of Microglia Enhances Proinflammatory Cytokine Release through EphA2/p38 MAPK Pathway in Alzheimer's Disease.
Ma X, Zhang Y, Gou D, Ma J, Du J, Wang C, Li S, Cui H
Journal of Alzheimer's disease : JAD 2022;88(2):771-785
Journal of Alzheimer's disease : JAD 2022;88(2):771-785
Probiotic Bifidobacterium breve Prevents Memory Impairment Through the Reduction of Both Amyloid-β Production and Microglia Activation in APP Knock-In Mouse.
Abdelhamid M, Zhou C, Ohno K, Kuhara T, Taslima F, Abdullah M, Jung CG, Michikawa M
Journal of Alzheimer's disease : JAD 2022;85(4):1555-1571
Journal of Alzheimer's disease : JAD 2022;85(4):1555-1571
Administration of miR-195 Inhibitor Enhances Memory Function Through Improving Synaptic Degradation and Mitochondrial Dysfunction of the Hippocampal Neurons in SAMP8 Mice.
Gao Z, Zhang R, Jiang L, Zhou H, Wang Q, Ma Y, Zhang D, Qin Y, Tian P, Zhang N, Shi Z, Xu S
Journal of Alzheimer's disease : JAD 2022;85(4):1495-1509
Journal of Alzheimer's disease : JAD 2022;85(4):1495-1509
Spatial Training Attenuates Long-Term Alzheimer's Disease-Related Pathogenic Processes in APP/PS1 Mice.
Zhao Y, Bao J, Liu W, Gong X, Liang Z, Li W, Wu M, Xiao Y, Sun B, Wang X, Wang JZ, Wang J, Shu X
Journal of Alzheimer's disease : JAD 2022;85(4):1453-1466
Journal of Alzheimer's disease : JAD 2022;85(4):1453-1466
3D-Printed β-Tricalcium Phosphate Scaffolds Promote Osteogenic Differentiation of Bone Marrow-Deprived Mesenchymal Stem Cells in an N6-methyladenosine-Dependent Manner.
Jiao X, Sun X, Li W, Chu W, Zhang Y, Li Y, Wang Z, Zhou X, Ma J, Xu C, Dai K, Wang J, Gan Y
International journal of bioprinting 2022;8(2):544
International journal of bioprinting 2022;8(2):544
Antitumor Effects of Astaxanthin on Esophageal Squamous Cell Carcinoma by up-Regulation of PPARγ.
Cui L, Li Z, Xu F, Tian Y, Chen T, Li J, Guo Y, Lyu Q
Nutrition and cancer 2022;74(4):1399-1410
Nutrition and cancer 2022;74(4):1399-1410
Lactobacillus acidophilus ATCC 4356 Exopolysaccharides Suppresses Mediators of Inflammation through the Inhibition of TLR2/STAT-3/P38-MAPK Pathway in DEN-Induced Hepatocarcinogenesis in Rats.
Khedr OMS, El-Sonbaty SM, Moawed FSM, Kandil EI, Abdel-Maksoud BE
Nutrition and cancer 2022;74(3):1037-1047
Nutrition and cancer 2022;74(3):1037-1047
LincRNA-p21 Upregulates Nuclear Orphan Receptor Nr4a2 and Aggravates Myocardial Ischemia/Reperfusion Injury via Targeting MiR-466i-5p.
Zhai X, Liu R, Li J, Wang F, Liu L, Wei S, Bian Y, Pang J, Xue M, Qin D, Wang S, Xu T, Xu F, Cao S, Yuan Q, Chen Y
International heart journal 2022;63(5):1004-1014
International heart journal 2022;63(5):1004-1014
Astragaloside IV - mediated endothelial progenitor cell exosomes promote autophagy and inhibit apoptosis in hyperglycemic damaged endothelial cells via miR-21/PTEN axis.
Xiong W, Huang XL, Li CY, Wang XL, Lan HW, Wang TT, Chen ZL, Yang QP, Hu AL, Xia YF, Zhu FR, Zhou ZZ
Folia histochemica et cytobiologica 2022;60(4):323-334
Folia histochemica et cytobiologica 2022;60(4):323-334
Neferine Suppresses Experimental Colitis-Associated Colorectal Cancer by Inhibition of NF-[Formula: see text]B p65 and STAT3.
Zhou Y, Xiang S, Zheng H, Hou Y, Wang Y, Li CC, Wu Q, Shi J, Chen X
The American journal of Chinese medicine 2022;50(5):1387-1400
The American journal of Chinese medicine 2022;50(5):1387-1400
Protective Effect of Ginsenosides from Stems and Leaves of Panax ginseng against Scopolamine-Induced Memory Damage via Multiple Molecular Mechanisms.
Wang Y, Zhang JJ, Hou JG, Li X, Liu W, Zhang JT, Zheng SW, Su FY, Li W
The American journal of Chinese medicine 2022;50(4):1113-1131
The American journal of Chinese medicine 2022;50(4):1113-1131
Effects of Capsaicin on the Hypoglycemic Regulation of Metformin and Gut Microbiota Profiles in Type 2 Diabetic Rats.
Kang ZQ, Hu JL, Chen MY, Mao Y, Xie LF, Yang N, Liu T, Zhang W, Huang WH
The American journal of Chinese medicine 2022;50(3):839-861
The American journal of Chinese medicine 2022;50(3):839-861
Proanthocyanidin oligomers extract from hawthorn mediates cell cycle arrest, apoptosis, and lysosome vacuolation on HCT116 cells.
Sun YS, Wang ZW, Gao Z, Zhao W, Thakur K, Zhong Q, Wei ZJ
Current research in food science 2022;5:904-917
Current research in food science 2022;5:904-917
Study on the Protective Effect of Schizandrin B against Acetaminophen-Induced Cytotoxicity in Human Hepatocyte.
Cheng L, Wang T, Gao Z, Wu W, Cao Y, Wang L, Zhang Q
Biological & pharmaceutical bulletin 2022;45(5):596-604
Biological & pharmaceutical bulletin 2022;45(5):596-604
RING-Finger Protein 6 promotes Drug Resistance in Retinoblastoma via JAK2/STAT3 Signaling Pathway.
Chai Y, Jiao S, Peng X, Gan Q, Chen L, Hu X, Hao L, Zhang S, Tao Q
Pathology oncology research : POR 2022;28:1610273
Pathology oncology research : POR 2022;28:1610273
Sufentanil Alleviates Sepsis-Induced Myocardial Injury and Stress Response in Rats through the ERK/GSK-3β Signaling Axis.
Zang H, Shao G, Lou Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9630716
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9630716
lncRNA IGF2-AS Regulates Nucleotide Metabolism by Mediating HMGA1 to Promote Pyroptosis of Endothelial Progenitor Cells in Sepsis Patients.
Liang G, Zeng M, Gao M, Xing W, Jin X, Wang Q, Deng L, Ou H, He Z
Oxidative medicine and cellular longevity 2022;2022:9369035
Oxidative medicine and cellular longevity 2022;2022:9369035
A Network Pharmacology Approach for Uncovering the Antitumor Effects and Potential Mechanisms of the Sijunzi Decoction for the Treatment of Gastric Cancer.
Ding P, Guo Y, Wang C, Chen J, Guo C, Liu H, Shi Q
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9364313
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9364313
Qingfei Tongluo Formula Mitigates Mycoplasma pneumoniae Infection via the PERK Signaling Pathway.
Liu X, Wang M, Kan Q, Lin Y, Jiang Z
Disease markers 2022;2022:9340353
Disease markers 2022;2022:9340353
Betaine Inhibits NLRP3 Inflammasome Hyperactivation and Regulates Microglial M1/M2 Phenotypic Differentiation, Thereby Attenuating Lipopolysaccharide-Induced Depression-Like Behavior.
Zhang M, Wang XL, Shi H, Meng LQ, Quan HF, Yan L, Yang HF, Peng XD
Journal of immunology research 2022;2022:9313436
Journal of immunology research 2022;2022:9313436
Hippocampal Mitochondrial Abnormalities Induced the Dendritic Complexity Reduction and Cognitive Decline in a Rat Model of Spinal Cord Injury.
Hu X, Wu L, Wen Y, Liu J, Li H, Zhang Y, Wang Z, Ding J, Zeng Z, Xia H
Oxidative medicine and cellular longevity 2022;2022:9253916
Oxidative medicine and cellular longevity 2022;2022:9253916
HSPB8 Overexpression Ameliorates Cognitive Impairment in Diabetic Mice via Inhibiting NLRP3 Inflammation Activation.
Chang Y, Wu Y, Jiang X, Zhu J, Wang C, Ma R, Li G
Oxidative medicine and cellular longevity 2022;2022:9251835
Oxidative medicine and cellular longevity 2022;2022:9251835
Electroacupuncture Preconditioning Alleviates Lipopolysaccharides-Induced Acute Lung Injury by Downregulating LC3-II/I and Beclin 1 Expression.
Sun G, Zeng Y, Luo F, Zhang L, Tan J, Tong J, Yang L, Liu D, Liu L, Zhou J
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8997173
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8997173
Sequential Treatment with Activin and Hepatocyte Growth Factor Induces FOXM1 to Promote Colorectal Cancer Liver Metastasis.
Peng H, Ye T, Deng L, Yang X, Jiang Z, Guo J
Canadian journal of gastroenterology & hepatology 2022;2022:8996203
Canadian journal of gastroenterology & hepatology 2022;2022:8996203
Cell-Dependent Pathogenic Roles of Filamin B in Different Skeletal Malformations.
Wu H, Wang Y, Chen X, Yao Y, Zhao W, Fang L, Sun X, Wang N, Jiang J, Gao L, Zhao J, Xu C
Oxidative medicine and cellular longevity 2022;2022:8956636
Oxidative medicine and cellular longevity 2022;2022:8956636
Activation of LRP1 Ameliorates Cerebral Ischemia/Reperfusion Injury and Cognitive Decline by Suppressing Neuroinflammation and Oxidative Stress through TXNIP/NLRP3 Signaling Pathway in Mice.
Yang CJ, Li X, Feng XQ, Chen Y, Feng JG, Jia J, Wei JC, Zhou J
Oxidative medicine and cellular longevity 2022;2022:8729398
Oxidative medicine and cellular longevity 2022;2022:8729398
Long Noncoding RNA ENSG00000254693 Promotes Diabetic Kidney Disease via Interacting with HuR.
Yu Q, Lin J, Ma Q, Li Y, Wang Q, Chen H, Liu Y, Liu B
Journal of diabetes research 2022;2022:8679548
Journal of diabetes research 2022;2022:8679548
Thioredoxin-Interacting Protein (TXNIP) Knockdown Protects against Sepsis-Induced Brain Injury and Cognitive Decline in Mice by Suppressing Oxidative Stress and Neuroinflammation.
Zhang Y, Xing CJ, Liu X, Li YH, Jia J, Feng JG, Yang CJ, Chen Y, Zhou J
Oxidative medicine and cellular longevity 2022;2022:8645714
Oxidative medicine and cellular longevity 2022;2022:8645714
Nr2f2 Overexpression Aggravates Ferroptosis and Mitochondrial Dysfunction by Regulating the PGC-1α Signaling in Diabetes-Induced Heart Failure Mice.
Miao W, Chen M, Chen M, Cui C, Zhu Y, Luo X, Wu B
Mediators of inflammation 2022;2022:8373389
Mediators of inflammation 2022;2022:8373389
MiR-205-5p Functions as a Tumor Suppressor in Gastric Cancer Cells through Downregulating FAM84B.
Chen X, Zhang L, Geng J, Chen Z, Cui X
Journal of oncology 2022;2022:8267891
Journal of oncology 2022;2022:8267891
Downregulated XBP-1 Rescues Cerebral Ischemia/Reperfusion Injury-Induced Pyroptosis via the NLRP3/Caspase-1/GSDMD Axis.
Zhang Y, Yao Z, Xiao Y, Zhang X, Liu J
Mediators of inflammation 2022;2022:8007078
Mediators of inflammation 2022;2022:8007078
miR-138-5p Inhibits the Growth and Invasion of Glioma Cells by Regulating WEE1.
Gong J, Tang Z, Yu Z, Deng Z, Liu Y, Ren N, Wang L, He Z
Analytical cellular pathology (Amsterdam) 2022;2022:7809882
Analytical cellular pathology (Amsterdam) 2022;2022:7809882
Hepatoblastoma: Derived Exosomal LncRNA NEAT1 Induces BMSCs Differentiation into Tumor-Supporting Myofibroblasts via Modulating the miR-132/MMP9 Axis.
Hu Y, Zai H, Jiang W, Ou Z, Yao Y, Zhu Q
Journal of oncology 2022;2022:7630698
Journal of oncology 2022;2022:7630698
Celastrol Protects against Cerebral Ischemia/Reperfusion Injury in Mice by Inhibiting Glycolysis through Targeting HIF-1α/PDK1 Axis.
Chen M, Liu M, Luo Y, Cao J, Zeng F, Yang L, Yang J, Tao T, Jiang Y
Oxidative medicine and cellular longevity 2022;2022:7420507
Oxidative medicine and cellular longevity 2022;2022:7420507
Protective Effect of Photobiomodulation against Hydrogen Peroxide-Induced Oxidative Damage by Promoting Autophagy through Inhibition of PI3K/AKT/mTOR Pathway in MC3T3-E1 Cells.
Zuo X, Wei X, Ju C, Wang X, Zhang Z, Ma Y, Zhu Z, Li X, Song Z, Luo L, Hu X, Wang Z
Oxidative medicine and cellular longevity 2022;2022:7223353
Oxidative medicine and cellular longevity 2022;2022:7223353
Preventive Effects of Ilex Cornuta Aqueous Extract on High-Fat Diet-Induced Fatty Liver of Mice.
Liu M, Jia H, He Y, Huan Y, Kong Z, Xu N, Cao X, Duan Y, Li Z, Yang L, Wei WP, Wang L, Li L
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7183471
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7183471
Metabolism-Related Gene TXNRD1 Regulates Inflammation and Oxidative Stress Induced by Cigarette Smoke through the Nrf2/HO-1 Pathway in the Small Airway Epithelium.
Huang Q, Peng M, Gu Y, Wu J, Zhan Y, Deng Z, Chen S, Yang R, Chen J, Xie J
Oxidative medicine and cellular longevity 2022;2022:7067623
Oxidative medicine and cellular longevity 2022;2022:7067623
Molecular Mechanisms Underlying the Effects of Bimin Kang Mixture on Allergic Rhinitis: Network Pharmacology and RNA Sequencing Analysis.
Qi LJ, Wang RZ, Gao S, Chen XJ, Zhang X, Zhang YP
BioMed research international 2022;2022:7034078
BioMed research international 2022;2022:7034078
Pygo1 Regulates the Behavior of Human Non-Small-Cell Lung Cancer via the Wnt/β-Catenin Pathway.
Wen Y, Li Y, Yang B, Guo X, Lin L, Liang J, Zhang K, Li X, Jiang Z, Wang Y, Li Y, Wu X, Fan X, Li F, Yuan W
Disease markers 2022;2022:6993994
Disease markers 2022;2022:6993994
Targeting Ferroptosis Attenuates Inflammation, Fibrosis, and Mast Cell Activation in Chronic Prostatitis.
Lin D, Zhang M, Luo C, Wei P, Cui K, Chen Z
Journal of immunology research 2022;2022:6833867
Journal of immunology research 2022;2022:6833867
Electroacupuncture at Zusanli Alleviates Sepsis by Regulating the TLR4-MyD88-NF-Kappa B Pathway and Diversity of Intestinal Flora.
Zhan L, Liu H, Zheng J, Meng J, Fu D, Pang L, Ji C
Evidence-based complementary and alternative medicine : eCAM 2022;2022:6706622
Evidence-based complementary and alternative medicine : eCAM 2022;2022:6706622
Effects of Electroacupuncture at Different Acupoints on Functional Dyspepsia Rats.
Li YJ, Yang NN, Huang J, Lin LL, Qi LY, Ma SM, Hu CX, Wang Y, Yang JW, Liu CZ
Evidence-based complementary and alternative medicine : eCAM 2022;2022:6548623
Evidence-based complementary and alternative medicine : eCAM 2022;2022:6548623
miR-127-5p Targets JAM3 to Regulate Ferroptosis, Proliferation, and Metastasis in Malignant Meningioma Cells.
Zhang J, Liu Z, Dong Y
Disease markers 2022;2022:6423237
Disease markers 2022;2022:6423237
Controlled Hemorrhage Sensitizes Angiotensin II-Elicited Hypertension through Activation of the Brain Renin-Angiotensin System Independently of Endoplasmic Reticulum Stress.
Wu GB, Du HB, Zhai JY, Sun S, Cui JL, Zhang Y, Zhao ZA, Wu JL, Johnson AK, Xue B, Zhao ZG, Zhang GS
Oxidative medicine and cellular longevity 2022;2022:6371048
Oxidative medicine and cellular longevity 2022;2022:6371048
The Gut Microbiota Dysbiosis in Preeclampsia Contributed to Trophoblast Cell Proliferation, Invasion, and Migration via lncRNA BC030099/NF-κB Pathway.
Tang R, Xiao G, Jian Y, Yuan Q, Jiang C, Wang W
Mediators of inflammation 2022;2022:6367264
Mediators of inflammation 2022;2022:6367264
Correlation Analysis of Umbilical Cord Blood Metabolic Phenotype and Inflammation in Patients with Gestational Diabetes Mellitus Complicated with Overweight and Obesity.
Chen Q, Li W, Deng Y, Li Y, Huang L, Zhao L, Li H
Evidence-based complementary and alternative medicine : eCAM 2022;2022:6072286
Evidence-based complementary and alternative medicine : eCAM 2022;2022:6072286
Expression of POT1-AS1 in GC Tissue, Its Effect on Biological Behavior of Gastric Cancer, and Its Significance on Prognosis of Gastric Cancer.
Jiang L, Yang L, Dai Y, Yang G, Pan S
Computational and mathematical methods in medicine 2022;2022:6021994
Computational and mathematical methods in medicine 2022;2022:6021994
Baicalin Alleviates Thrombin-Induced Inflammation in Vascular Smooth Muscle Cells.
Zheng X, Wang P, Jia M, Li Q, Zhang A, Zhou Q
BioMed research international 2022;2022:5799308
BioMed research international 2022;2022:5799308
The Traditional Chinese Medicine Formula FTZ Protects against Cardiac Fibrosis by Suppressing the TGFβ1-Smad2/3 Pathway.
Zhang Y, Wang D, Wu K, Shao X, Diao H, Wang Z, Sun M, Huang X, Li Y, Tang X, Yan M, Guo J
Evidence-based complementary and alternative medicine : eCAM 2022;2022:5642307
Evidence-based complementary and alternative medicine : eCAM 2022;2022:5642307
Xuesaitong Combined with Dexmedetomidine Improves Cerebral Ischemia-Reperfusion Injury in Rats by Activating Keap1/Nrf2 Signaling and Mitophagy in Hippocampal Tissue.
Han GJ, Min XZ, Ma SS, Ding C, Wang XQ
Oxidative medicine and cellular longevity 2022;2022:5126042
Oxidative medicine and cellular longevity 2022;2022:5126042
Quantitative Proteomics Analysis Expands the Roles of Lysine β-Hydroxybutyrylation Pathway in Response to Environmental β-Hydroxybutyrate.
Hou W, Liu G, Ren X, Liu X, He L, Huang H
Oxidative medicine and cellular longevity 2022;2022:4592170
Oxidative medicine and cellular longevity 2022;2022:4592170
Cepharanthine Attenuates Early Brain Injury after Subarachnoid Hemorrhage in Mice via Inhibiting 15-Lipoxygenase-1-Mediated Microglia and Endothelial Cell Ferroptosis.
Gao S, Zhou L, Lu J, Fang Y, Wu H, Xu W, Pan Y, Wang J, Wang X, Zhang J, Shao A
Oxidative medicine and cellular longevity 2022;2022:4295208
Oxidative medicine and cellular longevity 2022;2022:4295208
Silencing ATF3 Might Delay TBHP-Induced Intervertebral Disc Degeneration by Repressing NPC Ferroptosis, Apoptosis, and ECM Degradation.
Li Y, Pan D, Wang X, Huo Z, Wu X, Li J, Cao J, Xu H, Du L, Xu B
Oxidative medicine and cellular longevity 2022;2022:4235126
Oxidative medicine and cellular longevity 2022;2022:4235126
Inhibition of KCTD10 Affects Diabetic Retinopathy Progression by Reducing VEGF and Affecting Angiogenesis.
Feng Y, Wang C, Wang G
Genetics research 2022;2022:4112307
Genetics research 2022;2022:4112307
Preparation and Biocompatibility of Core-Shell Microspheres for Sequential, Sustained Release of BMP-2 and VEGF.
Liu Z, Xu Z, Wang X, Zhang Y, Wu Y, Jiang D, Jia R
BioMed research international 2022;2022:4072975
BioMed research international 2022;2022:4072975
Acidic Tumor Microenvironment Promotes Pancreatic Cancer through miR-451a/MEF2D Axis.
Xu J, Li Y, Li Z, Shao W, Song J, Wei J
Journal of oncology 2022;2022:3966386
Journal of oncology 2022;2022:3966386
The lncRNA KIF9-AS1 Accelerates Hepatocellular Carcinoma Growth by Recruiting DNMT1 to Promote RAI2 DNA Methylation.
Yu Y, Lu X, Yan Y, Wang Y, Meng J, Tian S, Mu J
Journal of oncology 2022;2022:3888798
Journal of oncology 2022;2022:3888798
Lycopene Improves Bone Quality and Regulates AGE/RAGE/NF-кB Signaling Pathway in High-Fat Diet-Induced Obese Mice.
Xia B, Zhu R, Zhang H, Chen B, Liu Y, Dai X, Ye Z, Zhao D, Mo F, Gao S, Wang XD, Bromme D, Wang L, Wang X, Zhang D
Oxidative medicine and cellular longevity 2022;2022:3697067
Oxidative medicine and cellular longevity 2022;2022:3697067
Identification of RPS7 as the Biomarker of Ferroptosis in Acute Kidney Injury.
Zhang H, Liu X, Zhou L, Deng Z, Wang Y
BioMed research international 2022;2022:3667339
BioMed research international 2022;2022:3667339
Prognostic Lnc-S100B-2 Affects Cell Apoptosis and Microenvironment of Colorectal Cancer through MLLT10 Signaling.
Yi J, Peng F, Zhao J, Gong X
Journal of oncology 2022;2022:3565118
Journal of oncology 2022;2022:3565118
Theaflavin-3,3'-Digallate Inhibits Erastin-Induced Chondrocytes Ferroptosis via the Nrf2/GPX4 Signaling Pathway in Osteoarthritis.
Xu C, Ni S, Xu N, Yin G, Yu Y, Zhou B, Zhao G, Wang L, Zhu R, Jiang S, Wang Y
Oxidative medicine and cellular longevity 2022;2022:3531995
Oxidative medicine and cellular longevity 2022;2022:3531995
miR-328-5p Induces Human Intervertebral Disc Degeneration by Targeting WWP2.
Yan J, Wu LG, Zhang M, Fang T, Pan W, Zhao JL, Zhou Q
Oxidative medicine and cellular longevity 2022;2022:3511967
Oxidative medicine and cellular longevity 2022;2022:3511967
Transcutaneous Electrical Acupoint Stimulation Ameliorates Cognitive Function through PINK1/Parkin Mediated Mitophagy in VD Rats.
Hu Z, Wen T, Hu K, Wang R, Su X, Ouyang W, Zhou J, Wen Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2810794
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2810794
Artemisinin and Its Derivate Alleviate Pulmonary Hypertension and Vasoconstriction in Rodent Models.
Bao C, He Q, Wang H, Sun Y, Xu Y, Pan Y, Hu Y, Zheng S, Liang S, Luo A, Nahar T, Chen J, Tang H, Han Y
Oxidative medicine and cellular longevity 2022;2022:2782429
Oxidative medicine and cellular longevity 2022;2022:2782429
Therapy-resistant and -sensitive lncRNAs, SNHG1 and UBL7-AS1 promote glioblastoma cell proliferation.
Cao M, Ma R, Li H, Cui J, Zhang C, Zhao J
Oxidative medicine and cellular longevity 2022;2022:2623599
Oxidative medicine and cellular longevity 2022;2022:2623599
Rhein Ameliorates Cognitive Impairment in an APP/PS1 Transgenic Mouse Model of Alzheimer's Disease by Relieving Oxidative Stress through Activating the SIRT1/PGC-1α Pathway.
Yin Z, Gao D, Du K, Han C, Liu Y, Wang Y, Gao X
Oxidative medicine and cellular longevity 2022;2022:2524832
Oxidative medicine and cellular longevity 2022;2022:2524832
The Pretreatment of Xiaoqinglong Decoction Alleviates Inflammation and Oxidative Damage and Up-Regulates Angiotensin-Converting Enzyme 2 in Lipopolysaccharide-Induced Septic Acute Lung Injury Rats.
Su JC, Cheng C, Wang CY, Zhang Y, He YT, Guo ZW, Liu XY, Liu WM, Zhang YJ, Xu SW, Zhang XY, Liu ZB, Zhang XF
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2421198
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2421198
Overexpression of PTPRZ1 Regulates p120/β-Catenin Phosphorylation to Promote Carcinogenesis of Oral Submucous Fibrosis.
Ma L, Shen T, Peng H, Wu J, Wang W, Gao X
Journal of oncology 2022;2022:2352360
Journal of oncology 2022;2022:2352360
High-Calcium Microenvironment during the Development of Kidney Calculi Can Promote Phenotypic Transformation of NRK-52E Cells by Inhibiting the Expression of Stromal Interaction Molecule-1.
Li LS, Zhu YP, Xia QD, Wang SG, He D
BioMed research international 2022;2022:2350198
BioMed research international 2022;2022:2350198
Mitochondrial Targeted Antioxidant SKQ1 Ameliorates Acute Kidney Injury by Inhibiting Ferroptosis.
Song J, Sheng J, Lei J, Gan W, Yang Y
Oxidative medicine and cellular longevity 2022;2022:2223957
Oxidative medicine and cellular longevity 2022;2022:2223957
Oleoylethanolamide Alleviates Hepatic Ischemia-Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress-Associated Apoptosis.
Qi S, Yan Q, Wang Z, Liu D, Zhan M, Du J, Chen L
PPAR research 2022;2022:2212996
PPAR research 2022;2022:2212996
Isoschaftoside Reverses Nonalcoholic Fatty Liver Disease via Activating Autophagy In Vivo and In Vitro.
Su Y, Kang Y, Yi J, Lin Q, Zhang C, Lin Z, Yan Z, Qu J, Liu J
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2122563
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2122563
Sestrin2 Overexpression Ameliorates Endoplasmic Reticulum Stress-Induced Apoptosis via Inhibiting mTOR Pathway in HepG2 Cells.
Hu H, Luo Z, Liu X, Huang L, Lu X, Ding R, Duan C, He Y
International journal of endocrinology 2022;2022:2009753
International journal of endocrinology 2022;2022:2009753
lncRNA GAS5 Sensitizes Breast Cancer Cells to Ionizing Radiation by Inhibiting DNA Repair.
Ma Y, Yu L, Yan W, Qiu L, Zhang J, Jia X
BioMed research international 2022;2022:1987519
BioMed research international 2022;2022:1987519
Hugan Buzure Induces Autophagy and Apoptosis in Hepatocellular Carcinoma by Inhibiting PI3K/Akt/mTOR Signaling Pathway.
Meng X, Li M, Qiao M, Li X, Yang J, Hu J
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1618491
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1618491
Tuftelin 1 Facilitates Hepatocellular Carcinoma Progression through Regulation of Lipogenesis and Focal Adhesion Maturation.
Zhu L, Zhou KX, Ma MZ, Yao LL, Zhang YL, Li H, Du C, Yang XM
Journal of immunology research 2022;2022:1590717
Journal of immunology research 2022;2022:1590717
Upregulation of Klotho Aggravates Insulin Resistance in Gestational Diabetes Mellitus Trophoblast Cells.
Lin L, Wang X, Zhao W, Chen Y
Genetics research 2022;2022:1500768
Genetics research 2022;2022:1500768
Ginsenoside Rg1 Reduces Oxidative Stress Via Nrf2 Activation to Regulate Age-Related Mesenchymal Stem Cells Fate Switch Between Osteoblasts and Adipocytes.
Hou J, Wang L, Wang C, Ma R, Wang Z, Xiao H, Zeng D, Ling L, Wang Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1411354
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1411354
Mitochondrial Transplantation Promotes Remyelination and Long-Term Locomotion Recovery following Cerebral Ischemia.
Chen T, Zhu Y, Jia J, Meng H, Xu C, Xian P, Li Z, Tang Z, Wu Y, Liu Y
Mediators of inflammation 2022;2022:1346343
Mediators of inflammation 2022;2022:1346343
PPARγ Alleviates Sepsis-Induced Liver Injury by Inhibiting Hepatocyte Pyroptosis via Inhibition of the ROS/TXNIP/NLRP3 Signaling Pathway.
Li Z, Liu T, Feng Y, Tong Y, Jia Y, Wang C, Cui R, Qu K, Liu C, Zhang J
Oxidative medicine and cellular longevity 2022;2022:1269747
Oxidative medicine and cellular longevity 2022;2022:1269747
Paeoniflorin attenuates monocrotaline-induced pulmonary arterial hypertension in rats by suppressing TAK1-MAPK/NF-κB pathways.
Yu M, Wu X, Wang J, He M, Han H, Hu S, Xu J, Yang M, Tan Q, Wang Y, Wang H, Xie W, Kong H
International journal of medical sciences 2022;19(4):681-694
International journal of medical sciences 2022;19(4):681-694
Upregulation of SQLE Contributes to Poor Survival in Head and Neck Squamous Cell Carcinoma.
Li J, Yang T, Wang Q, Li Y, Wu H, Zhang M, Qi H, Zhang H, Li J
International journal of biological sciences 2022;18(9):3576-3591
International journal of biological sciences 2022;18(9):3576-3591
Quantitative proteomics of HFD-induced fatty liver uncovers novel transcription factors of lipid metabolism.
Zhi S, Congcong Z, Zhiling G, Yihan Q, Yijing X, Guanjie L, Fang W, Xuehua S, Hongjie L, Xiaoni K, Yueqiu G
International journal of biological sciences 2022;18(8):3298-3312
International journal of biological sciences 2022;18(8):3298-3312
TDG suppresses the migration and invasion of human colon cancer cells via the DNMT3A/TIMP2 axis.
Miao J, Zhao C, Tang K, Xiong X, Wu F, Xue W, Duan B, Zhang H, Jing X, Li W, Sun Y, Hou N, Huang C
International journal of biological sciences 2022;18(6):2527-2539
International journal of biological sciences 2022;18(6):2527-2539
Mannan-Binding Lectin Deficiency Limits Inflammation-induced Myeloid-Derived Suppressor Cells Expansion via Modulating Tumor Necrosis Factor Alpha-triggered Apoptosis.
Dong L, Jiang H, Chen K, Xie J, An Q, Deng F, Sun Z, Liu Y, Zhou J, Zhang L, Lu X, Wang M, Chen Z, Zou X, Zuo D
International journal of biological sciences 2022;18(4):1580-1593
International journal of biological sciences 2022;18(4):1580-1593
Cancer-associated adipocytes promote the invasion and metastasis in breast cancer through LIF/CXCLs positive feedback loop.
Zhou C, He X, Tong C, Li H, Xie C, Wu Y, Wang L, Yan X, Luo D, Tang Y, Cheng Z, Xiong X
International journal of biological sciences 2022;18(4):1363-1380
International journal of biological sciences 2022;18(4):1363-1380
Hypoxic pancreatic cancer derived exosomal miR-30b-5p promotes tumor angiogenesis by inhibiting GJA1 expression.
Chen K, Wang Q, Liu X, Wang F, Yang Y, Tian X
International journal of biological sciences 2022;18(3):1220-1237
International journal of biological sciences 2022;18(3):1220-1237
Mir-484 contributes to diminished ovarian reserve by regulating granulosa cell function via YAP1-mediated mitochondrial function and apoptosis.
Li H, Wang X, Mu H, Mei Q, Liu Y, Min Z, Zhang L, Su P, Xiang W
International journal of biological sciences 2022;18(3):1008-1021
International journal of biological sciences 2022;18(3):1008-1021
Lactylation of PKM2 Suppresses Inflammatory Metabolic Adaptation in Pro-inflammatory Macrophages.
Wang J, Yang P, Yu T, Gao M, Liu D, Zhang J, Lu C, Chen X, Zhang X, Liu Y
International journal of biological sciences 2022;18(16):6210-6225
International journal of biological sciences 2022;18(16):6210-6225
P2RY13 Exacerbates Intestinal Inflammation by Damaging the Intestinal Mucosal Barrier via Activating IL-6/STAT3 Pathway.
Wu X, Wei S, Chen M, Li J, Wei Y, Zhang J, Dong W
International journal of biological sciences 2022;18(13):5056-5069
International journal of biological sciences 2022;18(13):5056-5069
A Novel ER Stress Mediator TMTC3 Promotes Squamous Cell Carcinoma Progression by Activating GRP78/PERK Signaling Pathway.
Yuan H, Zhao Z, Guo Z, Ma L, Han J, Song Y
International journal of biological sciences 2022;18(13):4853-4868
International journal of biological sciences 2022;18(13):4853-4868
The m6A-induced lncRNA CASC8 promotes proliferation and chemoresistance via upregulation of hnRNPL in esophageal squamous cell carcinoma.
Wu Q, Zhang H, Yang D, Min Q, Wang Y, Zhang W, Zhan Q
International journal of biological sciences 2022;18(13):4824-4836
International journal of biological sciences 2022;18(13):4824-4836
Deacetylation of Glutaminase by HDAC4 contributes to Lung Cancer Tumorigenesis.
Wang T, Lu Z, Han T, Wang Y, Gan M, Wang JB
International journal of biological sciences 2022;18(11):4452-4465
International journal of biological sciences 2022;18(11):4452-4465
RASAL2 mediated the enhancement of YAP1/TIAM1 signaling promotes malignant phenotypes of pancreatic ductal adenocarcinoma.
Yue Y, Wu K, Qian W, Zhu Z, Zhang S, Zhang W, Zhang W, Wu S, Li L, Wu Z, Ma Q, Xie K, Wang Z
International journal of biological sciences 2022;18(10):4245-4259
International journal of biological sciences 2022;18(10):4245-4259
Mechanosensitive Piezo1 is crucial for periosteal stem cell-mediated fracture healing.
Liu Y, Tian H, Hu Y, Cao Y, Song H, Lan S, Dai Z, Chen W, Zhang Y, Shao Z, Liu Y, Tong W
International journal of biological sciences 2022;18(10):3961-3980
International journal of biological sciences 2022;18(10):3961-3980
Enhanced Intracellular Reactive Oxygen Species by Photodynamic Therapy Effectively Promotes Chemoresistant Cell Death.
Xu X, Wang C, Zhang P, Gao X, Guan W, Wang F, Li X, Yuan J, Dou H, Xu G
International journal of biological sciences 2022;18(1):374-385
International journal of biological sciences 2022;18(1):374-385
Supplementation with dietary omega-3 PUFA mitigates fetal brain inflammation and mitochondrial damage caused by high doses of sodium nitrite in maternal rats.
Sun J, Zhang W
PloS one 2022;17(3):e0266084
PloS one 2022;17(3):e0266084
LncRNA LINC01857 reduces metastasis and angiogenesis in breast cancer cells via regulating miR-2052/CENPQ axis.
Qian W, Yang L, Ni Y, Yin F, Qin L, Yang Y
Open medicine (Warsaw, Poland) 2022;17(1):1357-1367
Open medicine (Warsaw, Poland) 2022;17(1):1357-1367
Long non-coding RNA NEAT1 promotes angiogenesis in hepatoma carcinoma via the miR-125a-5p/VEGF pathway.
Guo J, Yuan Q, Fang Y, Liao J, Zhang Z
Open life sciences 2022;17(1):1229-1239
Open life sciences 2022;17(1):1229-1239
NCOA4-Mediated Ferroptosis in Bronchial Epithelial Cells Promotes Macrophage M2 Polarization in COPD Emphysema.
Liu J, Zhang Z, Yang Y, Di T, Wu Y, Bian T
International journal of chronic obstructive pulmonary disease 2022;17:667-681
International journal of chronic obstructive pulmonary disease 2022;17:667-681
Study on the Local Anti-Osteoporosis Effect of Polaprezinc-Loaded Antioxidant Electrospun Membrane.
Gao X, Al-Baadani MA, Wu M, Tong N, Shen X, Ding X, Liu J
International journal of nanomedicine 2022;17:17-29
International journal of nanomedicine 2022;17:17-29
Pseudoephedrine Nanoparticles Alleviate Adriamycin-Induced Reproductive Toxicity Through the GnRhR Signaling Pathway.
Fu Y, Yuan P, Zheng Y, Wei Y, Gao L, Ruan Y, Chen Y, Li P, Feng W, Zheng X
International journal of nanomedicine 2022;17:1549-1566
International journal of nanomedicine 2022;17:1549-1566
Microglial activation in the motor cortex mediated NLRP3-related neuroinflammation and neuronal damage following spinal cord injury.
Hu X, Zhang Y, Wang L, Ding J, Li M, Li H, Wu L, Zeng Z, Xia H
Frontiers in cellular neuroscience 2022;16:956079
Frontiers in cellular neuroscience 2022;16:956079
The Role of Microglia/Macrophages Activation and TLR4/NF-κB/MAPK Pathway in Distraction Spinal Cord Injury-Induced Inflammation.
Liang W, Han B, Hai Y, Liu Y, Liu X, Yang J, Sun D, Yin P
Frontiers in cellular neuroscience 2022;16:926453
Frontiers in cellular neuroscience 2022;16:926453
Ursolic Acid Ameliorates Spinal Cord Injury in Mice by Regulating Gut Microbiota and Metabolic Changes.
Rong ZJ, Cai HH, Wang H, Liu GH, Zhang ZW, Chen M, Huang YL
Frontiers in cellular neuroscience 2022;16:872935
Frontiers in cellular neuroscience 2022;16:872935
MicroRNA-582-5p Contributes to the Maintenance of Neural Stem Cells Through Inhibiting Secretory Protein FAM19A1.
Zhang YF, Li XX, Cao XL, Ji CC, Gao XY, Gao D, Han H, Yu F, Zheng MH
Frontiers in cellular neuroscience 2022;16:866020
Frontiers in cellular neuroscience 2022;16:866020
Meningitic Escherichia coli-Induced Interleukin-17A Facilitates Blood-Brain Barrier Disruption via Inhibiting Proteinase 3/Protease-Activated Receptor 2 Axis.
Xu B, Chen J, Fu J, Yang R, Yang B, Huo D, Tan C, Chen H, Wang X
Frontiers in cellular neuroscience 2022;16:814867
Frontiers in cellular neuroscience 2022;16:814867
Anomalous Levels of CD47/Signal Regulatory Protein Alpha in the Hippocampus Lead to Excess Microglial Engulfment in Mouse Model of Perioperative Neurocognitive Disorders.
Shui M, Sun Y, Lin D, Xue Z, Liu J, Wu A, Wei C
Frontiers in neuroscience 2022;16:788675
Frontiers in neuroscience 2022;16:788675
Genetic Inhibition of Plppr5 Aggravates Hypoxic-Ischemie-Induced Cortical Damage and Excitotoxic Phenotype.
Sun Y, Jin MF, Li L, Liu Y, Wang D, Ni H
Frontiers in neuroscience 2022;16:751489
Frontiers in neuroscience 2022;16:751489
Anti-Inflammatory Effects and Molecular Mechanisms of Shenmai Injection in Treating Acute Pancreatitis: Network Pharmacology Analysis and Experimental Verification.
He Y, Hu C, Liu S, Xu M, Liang G, Du D, Liu T, Cai F, Chen Z, Tan Q, Deng L, Xia Q
Drug design, development and therapy 2022;16:2479-2495
Drug design, development and therapy 2022;16:2479-2495
The m6A RNA Modification Quantity and the Prognostic Effect of Reader YTHDC2 in Colorectal Cancer.
Liu T, Tang W, Chen Y, Liu Y, Xu D, Jiang Y, Zhou S, Qin X, Ren L, Chang W, Xu J
Clinical Medicine Insights. Oncology 2022;16:11795549221104441
Clinical Medicine Insights. Oncology 2022;16:11795549221104441
Excitatory and Inhibitory Synaptic Imbalance Caused by Brain-Derived Neurotrophic Factor Deficits During Development in a Valproic Acid Mouse Model of Autism.
Qi C, Chen A, Mao H, Hu E, Ge J, Ma G, Ren K, Xue Q, Wang W, Wu S
Frontiers in molecular neuroscience 2022;15:860275
Frontiers in molecular neuroscience 2022;15:860275
NF-κB and AP-1 are required for the lipopolysaccharide-induced expression of MCP-1, CXCL1, and Cx43 in cultured rat dorsal spinal cord astrocytes.
Lu Y, Li B, Xu A, Liang X, Xu T, Jin H, Xie Y, Wang R, Liu X, Gao X, Han Y, Zeng J
Frontiers in molecular neuroscience 2022;15:859558
Frontiers in molecular neuroscience 2022;15:859558
FGF15 Protects Septic Mice by Inhibiting Inflammation and Modulating Treg Responses.
Li X, Zhu Z, Xia Z, Xu B
Journal of inflammation research 2022;15:6187-6197
Journal of inflammation research 2022;15:6187-6197
Engeletin Alleviates the Inflammation and Apoptosis in Intervertebral Disc Degeneration via Inhibiting the NF-κB and MAPK Pathways.
Li B, Yang X, Zhang P, Guo J, Rong K, Wang X, Cao X, Zhou T, Zhao J
Journal of inflammation research 2022;15:5767-5783
Journal of inflammation research 2022;15:5767-5783
Chitosan/Sodium Alginate/Velvet Antler Blood Peptides Hydrogel Promotes Diabetic Wound Healing via Regulating Angiogenesis, Inflammatory Response and Skin Flora.
Hao M, Ding C, Sun S, Peng X, Liu W
Journal of inflammation research 2022;15:4921-4938
Journal of inflammation research 2022;15:4921-4938
Alpha-Momorcharin Inhibits Proinflammatory Cytokine Expression by M1 Macrophages but Not Anti-Inflammatory Cytokine Expression by M2 Macrophages.
Peng K, Deng N, Meng Y, He Q, Meng H, Luo T, Wei Y, Kang Y, Zhou X, Shen F
Journal of inflammation research 2022;15:4853-4872
Journal of inflammation research 2022;15:4853-4872
MULT1-Encoding DNA Alleviates Schistosomiasis-Associated Hepatic Fibrosis via Modulating Cellular Immune Response.
Yang L, Sun L, Cao Y, Wang Q, Song A, Zhu R, Liu W, Lu S
Journal of inflammation research 2022;15:4027-4045
Journal of inflammation research 2022;15:4027-4045
miR-17-5p Promotes Glucose Uptake of HTR8/SVneo Trophoblast Cells by Inhibiting TXNIP/NLRP3 Inflammasome Pathway.
Jiang Y, Wei L, Zhang H, Chen Y, Gao P, Zhang J, Zhou X, Zhu S, Du Y, Fang C, Li J, Feng L, He M, Wang S, Yu J
Diabetes, metabolic syndrome and obesity : targets and therapy 2022;15:3361-3374
Diabetes, metabolic syndrome and obesity : targets and therapy 2022;15:3361-3374
Effect of Azelaic Acid on Psoriasis Progression Investigated Based on Phosphatidylinositol 3-Kinase (PI3K)/Protein Kinase B (AKT) Signaling Pathway.
Li L, Lu H, Zhang Y, Li Q, Shi S, Liu Y
Clinical, cosmetic and investigational dermatology 2022;15:2523-2534
Clinical, cosmetic and investigational dermatology 2022;15:2523-2534
Identification of Biomarkers Related to Regulatory T Cell Infiltration in Oral Squamous Cell Carcinoma Based on Integrated Bioinformatics Analysis.
Wang C, Chen Z, Yang X, Zhang W, Zhou J, Zhang H, Ding X, Ye J, Wu H, Wu Y, Zheng Y, Song X
International journal of general medicine 2022;15:2361-2376
International journal of general medicine 2022;15:2361-2376
Mannan-Binding Lectin Regulates the Th17/Treg Axis Through JAK/STAT and TGF-β/SMAD Signaling Against Candida albicans Infection.
Wang F, Yang Y, Li Z, Wang Y, Zhang Z, Zhang W, Mu Y, Yang J, Yu L, Wang M
Journal of inflammation research 2022;15:1797-1810
Journal of inflammation research 2022;15:1797-1810
Shortening of the KHDRBS1 3'UTR by alternative cleavage and polyadenylation alters miRNA-mediated regulation and promotes gastric cancer progression.
Yu X, Kang W, Zhang J, Chen C, Liu Y
American journal of translational research 2022;14(9):6574-6585
American journal of translational research 2022;14(9):6574-6585
Arsenic exposure increases susceptibility to Ptpn11-induced malignancy in mouse embryonic fibroblasts through mitochondrial hypermetabolism.
Yang F, Tan Z, Dai Y, Wang X, Huang Z, Kan C, Wang S
American journal of translational research 2022;14(7):4591-4605
American journal of translational research 2022;14(7):4591-4605
TM9SF4 Is a Crucial Regulator of Inflammation and ER Stress in Inflammatory Bowel Disease.
Xie M, Mak JWY, Yu H, Cheng CTY, Chan HCH, Chan TT, Lau LHS, Wong MTL, Ko WH, Jiang L, Yao X
Cellular and molecular gastroenterology and hepatology 2022;14(2):245-270
Cellular and molecular gastroenterology and hepatology 2022;14(2):245-270
GDF15 negatively regulates RGS16 to impair hepatic lipid metabolism in male mice offspring conceived by in vitro fertilization.
Liu J, Zhu Y, Zhu D, Shi Y, Lu L, Li W, Li L, Zhou X, Zhang P, Yang H, Li M, Wang B, Sun M
American journal of translational research 2022;14(10):7535-7551
American journal of translational research 2022;14(10):7535-7551
The CEL-HYB1 Hybrid Allele Promotes Digestive Enzyme Misfolding and Pancreatitis in Mice.
Mao XT, Zou WB, Cao Y, Wang YC, Deng SJ, Cooper DN, Férec C, Li ZS, Chen JM, Liao Z
Cellular and molecular gastroenterology and hepatology 2022;14(1):55-74
Cellular and molecular gastroenterology and hepatology 2022;14(1):55-74
Presenilin Deficiency Increases Susceptibility to Oxidative Damage in Fibroblasts.
Zou K, Islam S, Sun Y, Gao Y, Nakamura T, Komano H, Tomita T, Michikawa M
Frontiers in aging neuroscience 2022;14:902525
Frontiers in aging neuroscience 2022;14:902525
Role of BDNF/ProBDNF Imbalance in Postoperative Cognitive Dysfunction by Modulating Synaptic Plasticity in Aged Mice.
Xue Z, Shui M, Lin X, Sun Y, Liu J, Wei C, Wu A, Li T
Frontiers in aging neuroscience 2022;14:780972
Frontiers in aging neuroscience 2022;14:780972
Identification of Key Genes and FUNCTIONAL Pathway in Radioresistance of Non-Small Cell Lung Cancer.
Li S, Feng J, Weng H, Zhao F, Cui G, Fu W, Lin X, Hu H
Cancer management and research 2022;14:2871-2884
Cancer management and research 2022;14:2871-2884
AKAP9 Upregulation Predicts Unfavorable Prognosis in Pediatric Acute Myeloid Leukemia and Promotes Stemness Properties via the Wnt/β-Catenin Pathway.
Wu S, Shen D, Zhao L
Cancer management and research 2022;14:157-167
Cancer management and research 2022;14:157-167
Circular RNA circASPM promotes the progression of glioblastoma by acting as a competing endogenous RNA to regulate miR-130b-3p/E2F1 axis.
Hou D, Wang Z, Li H, Liu J, Liu Y, Jiang Y, Lou M
Journal of Cancer 2022;13(5):1664-1678
Journal of Cancer 2022;13(5):1664-1678
Targeting HNRNPM Inhibits Cancer Stemness and Enhances Antitumor Immunity in Wnt-activated Hepatocellular Carcinoma.
Zhu GQ, Wang Y, Wang B, Liu WR, Dong SS, Chen EB, Cai JL, Wan JL, Du JX, Song LN, Chen SP, Yu L, Zhou ZJ, Wang Z, Zhou J, Shi YH, Fan J, Dai Z
Cellular and molecular gastroenterology and hepatology 2022;13(5):1413-1447
Cellular and molecular gastroenterology and hepatology 2022;13(5):1413-1447
Loss of SPTBN1 Suppresses Autophagy Via SETD7-mediated YAP Methylation in Hepatocellular Carcinoma Initiation and Development.
Chen S, Wu H, Wang Z, Jia M, Guo J, Jin J, Li X, Meng D, Lin L, He AR, Zhou P, Zhi X
Cellular and molecular gastroenterology and hepatology 2022;13(3):949-973.e7
Cellular and molecular gastroenterology and hepatology 2022;13(3):949-973.e7
Epigenetic modifications inhibit the expression of MARVELD1 and in turn tumorigenesis by regulating the Wnt/β-catenin pathway in pan-cancer.
Zhang J, Li Q, Sun Q, Wang B, Cui Y, Lou C, Yao Y, Zhang Y
Journal of Cancer 2022;13(1):225-242
Journal of Cancer 2022;13(1):225-242
Akkermansia muciniphila administration exacerbated the development of colitis-associated colorectal cancer in mice.
Wang F, Cai K, Xiao Q, He L, Xie L, Liu Z
Journal of Cancer 2022;13(1):124-133
Journal of Cancer 2022;13(1):124-133
Temporally integrated transcriptome analysis reveals ASFV pathology and host response dynamics.
Lv L, Zhang T, Jia H, Zhang Y, Ahsan A, Zhao X, Chen T, Shen Z, Shen N
Frontiers in immunology 2022;13:995998
Frontiers in immunology 2022;13:995998
Photobiomodulation promotes repair following spinal cord injury by restoring neuronal mitochondrial bioenergetics via AMPK/PGC-1α/TFAM pathway.
Zhu Z, Wang X, Song Z, Zuo X, Ma Y, Zhang Z, Ju C, Liang Z, Li K, Hu X, Wang Z
Frontiers in pharmacology 2022;13:991421
Frontiers in pharmacology 2022;13:991421
Connective tissue disease-related interstitial lung disease is alleviated by tripterine through inhibition of the PI3K/Akt, apoptosis, and TNF-α signalling pathways.
Zhu W, Wang Y, Liu C, Wu Y, Li Y, Wang Y
Frontiers in pharmacology 2022;13:990760
Frontiers in pharmacology 2022;13:990760
Herpes simplex virus type 2 inhibits TNF-α-induced NF-κB activation through viral protein ICP22-mediated interaction with p65.
Hu H, Fu M, Li C, Zhang B, Li Y, Hu Q, Zhang M
Frontiers in immunology 2022;13:983502
Frontiers in immunology 2022;13:983502
MiR-146b-5p/TRAF6 axis is essential for Ginkgo biloba L. extract GBE to attenuate LPS-induced neuroinflammation.
Liu M, Peng Y, Che Y, Zhou M, Bai Y, Tang W, Huang S, Zhang B, Deng S, Wang C, Yu Z
Frontiers in pharmacology 2022;13:978587
Frontiers in pharmacology 2022;13:978587
Anti-inflammatory, antioxidant and anti-virulence roles of atractylodin in attenuating Listeria monocytogenes infection.
Xu L, Zhou Y, Xu J, Xu X, Lu G, Lv Q, Wei L, Deng X, Shen X, Feng H, Wang J
Frontiers in immunology 2022;13:977051
Frontiers in immunology 2022;13:977051
Annexin A2 regulates Mycoplasma bovis adhesion and invasion to embryo bovine lung cells affecting molecular expression essential to inflammatory response.
Zhang H, Lu D, Zhang Y, Zhao G, Raheem A, Chen Y, Chen X, Hu C, Chen H, Yang L, Guo A
Frontiers in immunology 2022;13:974006
Frontiers in immunology 2022;13:974006
Cannabidiol prevents methamphetamine-induced neurotoxicity by modulating dopamine receptor D1-mediated calcium-dependent phosphorylation of methyl-CpG-binding protein 2.
Shen B, Zhang R, Yang G, Peng Y, Nie Q, Yu H, Dong W, Chen B, Song C, Tian Y, Qin L, Shu J, Hong S, Li L
Frontiers in pharmacology 2022;13:972828
Frontiers in pharmacology 2022;13:972828
Calycosin attenuates renal ischemia/reperfusion injury by suppressing NF-κB mediated inflammation via PPARγ/EGR1 pathway.
Zhang N, Guan C, Liu Z, Li C, Yang C, Xu L, Niu M, Zhao L, Zhou B, Che L, Wang Y, Xu Y
Frontiers in pharmacology 2022;13:970616
Frontiers in pharmacology 2022;13:970616
Coxsackievirus B3 infection induces glycolysis to facilitate viral replication.
Qian Y, Yang Y, Qing W, Li C, Kong M, Kang Z, Zuo Y, Wu J, Yu M, Yang Z
Frontiers in microbiology 2022;13:962766
Frontiers in microbiology 2022;13:962766
Enterovirus A71 utilizes host cell lipid β-oxidation to promote its replication.
Yang X, Chen J, Lu Z, Huang S, Zhang S, Cai J, Zhou Y, Cao G, Yu J, Qin Z, Zhao W, Zhang B, Zhu L
Frontiers in microbiology 2022;13:961942
Frontiers in microbiology 2022;13:961942
Creatinine accelerates APAP-induced liver damage by increasing oxidative stress through ROS/JNK signaling pathway.
Liu F, Liu Y, Peng Q, Wang G, Tan Q, Ou Z, Xu Q, Liu C, Zuo D, Zhao J
Frontiers in pharmacology 2022;13:959497
Frontiers in pharmacology 2022;13:959497
Vaccarin alleviates endothelial inflammatory injury in diabetes by mediating miR-570-3p/HDAC1 pathway.
Li T, Yu X, Zhu X, Wen Y, Zhu M, Cai W, Hou B, Xu F, Qiu L
Frontiers in pharmacology 2022;13:956247
Frontiers in pharmacology 2022;13:956247
SMO mutation predicts the effect of immune checkpoint inhibitor: From NSCLC to multiple cancers.
Ji W, Niu X, Yu Y, Li Z, Gu L, Lu S
Frontiers in immunology 2022;13:955800
Frontiers in immunology 2022;13:955800
Chrysophanol-8-O-glucoside protects mice against acute liver injury by inhibiting autophagy in hepatic stellate cells and inflammatory response in liver-resident macrophages.
Wang T, Lu Z, Qu XH, Xiong ZY, Wu YT, Luo Y, Zhang ZY, Han XJ, Xie CF
Frontiers in pharmacology 2022;13:951521
Frontiers in pharmacology 2022;13:951521
Therapeutic effects and mechanisms of N-(9,10-anthraquinone-2-ylcarbonyl) xanthine oxidase inhibitors on hyperuricemia.
Gao T, Xu J, Xiao Y, Li J, Hu W, Su X, Shen X, Yu W, Chen Z, Huang B, Li H, Wang X
Frontiers in pharmacology 2022;13:950699
Frontiers in pharmacology 2022;13:950699
Network pharmacology and experimental analysis to reveal the mechanism of Dan-Shen-Yin against endothelial to mesenchymal transition in atherosclerosis.
Hong M, Wu Y, Zhang H, Gu J, Chen J, Guan Y, Qin X, Li Y, Cao J
Frontiers in pharmacology 2022;13:946193
Frontiers in pharmacology 2022;13:946193
(±)-5-bromo-2-(5-fluoro-1-hydroxyamyl) Benzoate Protects Against Oxidative Stress Injury in PC12 Cells Exposed to H(2)O(2) Through Activation of Nrf2 Pathway.
Qi S, Zhang X, Fu Z, Pi A, Shi F, Fan Y, Zhang J, Xiao T, Shang D, Lin M, Gao N, Chang J, Gao Y
Frontiers in pharmacology 2022;13:943111
Frontiers in pharmacology 2022;13:943111
Mycoplasma bovis inhibits autophagy in bovine mammary epithelial cells via a PTEN/PI3K-Akt-mTOR-dependent pathway.
Xu M, Liu Y, Mayinuer T, Lin Y, Wang Y, Gao J, Wang D, Kastelic JP, Han B
Frontiers in microbiology 2022;13:935547
Frontiers in microbiology 2022;13:935547
Identification of the effect and mechanism of Yiyi Fuzi Baijiang powder against colorectal cancer using network pharmacology and experimental validation.
Xiang B, Geng R, Zhang Z, Ji X, Zou J, Chen L, Liu J
Frontiers in pharmacology 2022;13:929836
Frontiers in pharmacology 2022;13:929836
PM2.5 Synergizes With Pseudomonas aeruginosa to Suppress Alveolar Macrophage Function in Mice Through the mTOR Pathway.
Zhang J, Liu C, Zhao G, Li M, Ma D, Meng Q, Tang W, Huang Q, Shi P, Li Y, Jiang L, Yu X, Zhu H, Chen G, Zhang X
Frontiers in pharmacology 2022;13:924242
Frontiers in pharmacology 2022;13:924242
Transcriptomic Analysis of Dysregulated Genes of the nDNA-mtDNA Axis in a Mouse Model of Dilated Cardiomyopathy.
Ziemann M, Wu W, Deng XL, Du XJ
Frontiers in genetics 2022;13:921610
Frontiers in genetics 2022;13:921610
Allyl methyl trisulfide protected against LPS-induced acute lung injury in mice via inhibition of the NF-κB and MAPK pathways.
Wang S, Liu J, Dong J, Fan Z, Wang F, Wu P, Li X, Kou R, Chen F
Frontiers in pharmacology 2022;13:919898
Frontiers in pharmacology 2022;13:919898
Role of complement C1q/C3-CR3 signaling in brain injury after experimental intracerebral hemorrhage and the effect of minocycline treatment.
Zheng Y, Fan L, Xia S, Yang Q, Zhang Z, Chen H, Zeng H, Fu X, Peng Y, Xu C, Yu K, Liu F, Cao S
Frontiers in immunology 2022;13:919444
Frontiers in immunology 2022;13:919444
Reduced Immunity Regulator MAVS Contributes to Non-Hypertrophic Cardiac Dysfunction by Disturbing Energy Metabolism and Mitochondrial Homeostasis.
Wang Q, Sun Z, Cao S, Lin X, Wu M, Li Y, Yin J, Zhou W, Huang S, Zhang A, Zhang Y, Xia W, Jia Z
Frontiers in immunology 2022;13:919038
Frontiers in immunology 2022;13:919038
Yi-Shen-Hua-Shi Granule Alleviates Adriamycin-Induced Glomerular Fibrosis by Suppressing the BMP2/Smad Signaling Pathway.
Tan Z, Si Y, Yu Y, Ding J, Huang L, Xu Y, Zhang H, Lu Y, Wang C, Yu B, Yuan L
Frontiers in pharmacology 2022;13:917428
Frontiers in pharmacology 2022;13:917428
ATP-citrate lyase inhibitor improves ectopic lipid accumulation in the kidney in a db/db mouse model.
Zhan Z, Li A, Zhang W, Wu X, He J, Li Z, Li Y, Sun J, Zhang H
Frontiers in endocrinology 2022;13:914865
Frontiers in endocrinology 2022;13:914865
Berberrubine, a Main Metabolite of Berberine, Alleviates Non-Alcoholic Fatty Liver Disease via Modulating Glucose and Lipid Metabolism and Restoring Gut Microbiota.
Yang S, Cao S, Li C, Zhang J, Liu C, Qiu F, Kang N
Frontiers in pharmacology 2022;13:913378
Frontiers in pharmacology 2022;13:913378
Cisplatin-Induced Anorexia and Pica Behavior in Rats Enhanced by Chronic Stress Pretreatment.
Guo Z, Duan J, Chen Y, Cai W, Yang C, Yang Z, Liu X, Xu F
Frontiers in pharmacology 2022;13:913124
Frontiers in pharmacology 2022;13:913124
Curcumol Suppresses CCF-Mediated Hepatocyte Senescence Through Blocking LC3B-Lamin B1 Interaction in Alcoholic Fatty Liver Disease.
Qi X, Zheng S, Ma M, Lian N, Wang H, Chen L, Song A, Lu C, Zheng S, Jin H
Frontiers in pharmacology 2022;13:912825
Frontiers in pharmacology 2022;13:912825
Empagliflozin Attenuates Obesity-Related Kidney Dysfunction and NLRP3 Inflammasome Activity Through the HO-1-Adiponectin Axis.
Ye T, Zhang J, Wu D, Shi J, Kuang Z, Ma Y, Xu Q, Chen B, Kan C, Sun X, Han F
Frontiers in endocrinology 2022;13:907984
Frontiers in endocrinology 2022;13:907984
Total extract of Abelmoschus manihot L. alleviates uric acid-induced renal tubular epithelial injury via inhibition of caspase-8/caspase-3/NLRP3/GSDME signaling.
Ding Z, Zhao J, Wang X, Li W, Chen C, Yong C, Zhu Y, Tian F, Liu L, Yu M, Zhou E, Gu L, Yao C, Gao K
Frontiers in pharmacology 2022;13:907980
Frontiers in pharmacology 2022;13:907980
Furfural Produces Dose-Dependent Attenuating Effects on Ethanol-Induced Toxicity in the Liver.
Cheng Z, Luo X, Zhu Z, Huang Y, Yan X
Frontiers in pharmacology 2022;13:906933
Frontiers in pharmacology 2022;13:906933
Ninjinyoeito improves social behavior disorder in neuropeptide Y deficient zebrafish.
Kawabe M, Nishida T, Horita C, Ikeda A, Takahashi R, Inui A, Shiozaki K
Frontiers in pharmacology 2022;13:905711
Frontiers in pharmacology 2022;13:905711
A Mechanistic Exploratory Study on the Therapeutic Efficacy of Astragaloside IV Against Diabetic Retinopathy Revealed by Network Pharmacology.
Zhao ZH, Xu M, Fu C, Huang Y, Wang TH, Zuo ZF, Liu XZ
Frontiers in pharmacology 2022;13:903485
Frontiers in pharmacology 2022;13:903485
Csf2ra deletion attenuates acute lung injuries induced by intratracheal inoculation of aerosolized ricin in mice.
Zong F, Li S, Wang Y, Xiao N, Deng M, Zhang Z, Su D, Gao B, Zhou D, Hu L, Yang H
Frontiers in immunology 2022;13:900755
Frontiers in immunology 2022;13:900755
USP7 Promotes deubiquitination and stabilization of MyD88 to enhance immune responses.
Zhang N, Wang F, Zhang G, Zhang Q, Liu Y, Wang Q, Elsharkawy MS, Zheng M, Wen J, Zhao G, Li Q
Frontiers in immunology 2022;13:900243
Frontiers in immunology 2022;13:900243
Transcriptomics and Network Pharmacology Reveal the Protective Effect of Chaiqin Chengqi Decoction on Obesity-Related Alcohol-Induced Acute Pancreatitis via Oxidative Stress and PI3K/Akt Signaling Pathway.
Yang X, Yao L, Yuan M, Zhang X, Jakubowska MA, Ferdek PE, Dai L, Yang J, Jin T, Deng L, Fu X, Du D, Liu T, Criddle DN, Sutton R, Huang W, Xia Q
Frontiers in pharmacology 2022;13:896523
Frontiers in pharmacology 2022;13:896523
Astragalus-Scorpion Drug Pair Inhibits the Development of Prostate Cancer by Regulating GDPD4-2/PI3K/AKT/mTOR Pathway and Autophagy.
You X, Wu Y, Li Q, Sheng W, Zhou Q, Fu W
Frontiers in pharmacology 2022;13:895696
Frontiers in pharmacology 2022;13:895696
Natural Compound Library Screening Identifies Oroxin A for the Treatment of Myocardial Ischemia/Reperfusion Injury.
Cheng X, Huang T, Wang C, Hao S, Shu L, Wang S, Cheng G, Zhang Q, Huang J, Chen C
Frontiers in pharmacology 2022;13:894899
Frontiers in pharmacology 2022;13:894899
EGFR Activation Impairs Antiviral Activity of Interferon Signaling in Brain Microvascular Endothelial Cells During Japanese Encephalitis Virus Infection.
Zhang YG, Chen HW, Zhang HX, Wang K, Su J, Chen YR, Wang XR, Fu ZF, Cui M
Frontiers in microbiology 2022;13:894356
Frontiers in microbiology 2022;13:894356
A ROCK1 Inhibitior Fasudil Alleviates Cardiomyocyte Apoptosis in Diabetic Cardiomyopathy by Inhibiting Mitochondrial Fission in a Type 2 Diabetes Mouse Model.
Fan X, Li X, Liu H, Xu F, Ji X, Chen Y, Li C
Frontiers in pharmacology 2022;13:892643
Frontiers in pharmacology 2022;13:892643
Oridonin Delays Aging Through the AKT Signaling Pathway.
An Y, Zhu J, Wang X, Sun X, Luo C, Zhang Y, Ye Y, Li X, Abulizi A, Huang Z, Zhang H, Yang B, Xie Z
Frontiers in pharmacology 2022;13:888247
Frontiers in pharmacology 2022;13:888247
TIPE2 May Target the Nrf2/HO-1 Pathway to Inhibit M1 Macrophage-Related Neutrophilic Inflammation in Asthma.
Shi B, Hao Y, Li W, Dong H, Xu M, Gao P
Frontiers in immunology 2022;13:883885
Frontiers in immunology 2022;13:883885
Engineered Exosomes-Mediated Transfer of hsa-miR-320a Overcomes Chemoresistance in Cervical Cancer Cells via Targeting MCL1.
Zhou J, Wang Y, Zhang L, Chen Q, Zhu X, Jiang P, Jiang N, Zhao W, Li B
Frontiers in pharmacology 2022;13:883445
Frontiers in pharmacology 2022;13:883445
Pan-Cancer Analysis of the Immunological Role of PDIA5: A Potential Target for Immunotherapy.
Chen Y, He J, Chen R, Wang Z, Dai Z, Liang X, Wu W, Luo P, Zhang J, Peng Y, Zhang N, Liu Z, Zhang L, Zhang H, Cheng Q
Frontiers in immunology 2022;13:881722
Frontiers in immunology 2022;13:881722
Host MKRN1-Mediated Mycobacterial PPE Protein Ubiquitination Suppresses Innate Immune Response.
Dou Y, Xie Y, Zhang L, Liu S, Xu D, Wei Y, Li Y, Zhang XL
Frontiers in immunology 2022;13:880315
Frontiers in immunology 2022;13:880315
Hepatotoxicity of the Major Anthraquinones Derived From Polygoni Multiflori Radix Based on Bile Acid Homeostasis.
Kang L, Li D, Jiang X, Zhang Y, Pan M, Hu Y, Si L, Zhang Y, Huang J
Frontiers in pharmacology 2022;13:878817
Frontiers in pharmacology 2022;13:878817
Clinical significance of SPOCK2 expression signature for high-grade serous ovarian cancer patients.
Jiao M, Sun W, Li L, Li C, Zhou J, Li Q, Duan L
Frontiers in genetics 2022;13:878123
Frontiers in genetics 2022;13:878123
Baohuoside I Inhibits Osteoclastogenesis and Protects Against Ovariectomy-Induced Bone Loss.
Ma M, Fan AY, Liu Z, Yang LQ, Huang JM, Pang ZY, Yin F
Frontiers in pharmacology 2022;13:874952
Frontiers in pharmacology 2022;13:874952
Ginsenoside Rb1 Ameliorated Bavachin-Induced Renal Fibrosis via Suppressing Bip/eIF2α/CHOP Signaling-Mediated EMT.
Ni YH, Deng HF, Zhou L, Huang CS, Wang NN, Yue LX, Li GF, Yu HJ, Zhou W, Gao Y
Frontiers in pharmacology 2022;13:872474
Frontiers in pharmacology 2022;13:872474
Effects of Pereskia aculeate Miller Petroleum Ether Extract on Complete Freund's Adjuvant-Induced Rheumatoid Arthritis in Rats and its Potential Molecular Mechanisms.
Chen Y, Liu K, Qin Y, Chen S, Guan G, Huang Y, Chen Y, Mo Z
Frontiers in pharmacology 2022;13:869810
Frontiers in pharmacology 2022;13:869810
Knockdown of NRSF Alleviates Ischemic Brain Injury and Microvasculature Defects in Diabetic MCAO Mice.
He CF, Xue WJ, Xu XD, Wang JT, Wang XR, Feng Y, Zhou HG, Guo JC
Frontiers in neurology 2022;13:869220
Frontiers in neurology 2022;13:869220
Vitamin D3 Suppresses Human Cytomegalovirus-Induced Vascular Endothelial Apoptosis via Rectification of Paradoxical m6A Modification of Mitochondrial Calcium Uniporter mRNA, Which Is Regulated by METTL3 and YTHDF3.
Zhu W, Zhang H, Wang S
Frontiers in microbiology 2022;13:861734
Frontiers in microbiology 2022;13:861734
Single Cell Dissection of Epithelial-Immune Cellular Interplay in Acute Kidney Injury Microenvironment.
Zhang M, Wu L, Deng Y, Peng F, Wang T, Zhao Y, Chen P, Liu J, Cai G, Wang L, Wu J, Chen X
Frontiers in immunology 2022;13:857025
Frontiers in immunology 2022;13:857025
AQP2 Promotes Astrocyte Activation by Modulating the TLR4/NFκB-p65 Pathway Following Intracerebral Hemorrhage.
Deng S, Chen X, Lei Q, Lu W
Frontiers in immunology 2022;13:847360
Frontiers in immunology 2022;13:847360
The Construction and Immunogenicity Analyses of Recombinant Pseudorabies Virus With NADC30-Like Porcine Reproductive and Respiratory Syndrome Virus-Like Particles Co-expression.
Zhao J, Zhu L, Xu L, Li F, Deng H, Huang Y, Gu S, Sun X, Zhou Y, Xu Z
Frontiers in microbiology 2022;13:846079
Frontiers in microbiology 2022;13:846079
Saikosaponin D Inhibited IL-1β Induced ATDC 5 Chondrocytes Apoptosis In Vitro and Delayed Articular Cartilage Degeneration in OA Model Mice In Vivo.
Wu X, Zhao K, Fang X, Lu F, Cheng P, Song X, Zhang W, Yao C, Zhu J, Chen H
Frontiers in pharmacology 2022;13:845959
Frontiers in pharmacology 2022;13:845959
Network Pharmacology-Based Strategy to Identify the Pharmacological Mechanisms of Pulsatilla Decoction against Crohn's Disease.
Liu J, Zhang L, Wang Z, Chen S, Feng S, He Y, Zhang S
Frontiers in pharmacology 2022;13:844685
Frontiers in pharmacology 2022;13:844685
Dan-Shen-Yin Granules Prevent Hypoxia-Induced Pulmonary Hypertension via STAT3/HIF-1α/VEGF and FAK/AKT Signaling Pathways.
Wang RR, Yuan TY, Chen D, Chen YC, Sun SC, Wang SB, Kong LL, Fang LH, Du GH
Frontiers in pharmacology 2022;13:844400
Frontiers in pharmacology 2022;13:844400
Exogenous Linoleic Acid Intervention Alters Hepatic Glucose Metabolism in an Avian Embryo Model.
Zhang X, Wu Q, Zheng W, Liu C, Huang L, Zuo X, Xiao W, Han X, Ye H, Wang W, Zhu Y, Yang L
Frontiers in physiology 2022;13:844148
Frontiers in physiology 2022;13:844148
Polysaccharides From the Aerial Parts of Tetrastigma Hemsleyanum Diels et Gilg Induce Bidirectional Immunity and Ameliorate LPS-Induced Acute Respiratory Distress Syndrome in Mice.
Lu J, Zhu B, Zhou F, Ding X, Qian C, Ding Z, Ye X
Frontiers in pharmacology 2022;13:838873
Frontiers in pharmacology 2022;13:838873
Effect of Xiongmatang Extract on Behavioral and TRPV1-CGRP/CGRP-R Pathway in Rats With Migraine.
Liu D, Chang L, Wang J, Zhu Q, Jiang N, Azhar M, Ahmed A, Zeng G
Frontiers in pharmacology 2022;13:835187
Frontiers in pharmacology 2022;13:835187
Dihydromyricetin Alleviates Pulmonary Fibrosis by Regulating Abnormal Fibroblasts Through the STAT3/p-STAT3/GLUT1 Signaling Pathway.
Li Z, Geng J, Xie B, He J, Wang J, Peng L, Hu Y, Dai H, Wang C
Frontiers in pharmacology 2022;13:834604
Frontiers in pharmacology 2022;13:834604
Antigen Presentation Machinery Signature-Derived CALR Mediates Migration, Polarization of Macrophages in Glioma and Predicts Immunotherapy Response.
Chen R, Zhang H, Wu W, Li S, Wang Z, Dai Z, Liu Z, Zhang J, Luo P, Xia Z, Cheng Q
Frontiers in immunology 2022;13:833792
Frontiers in immunology 2022;13:833792
Lactobacillus plantarum RS-09 Induces M1-Type Macrophage Immunity Against Salmonella Typhimurium Challenge via the TLR2/NF-κB Signalling Pathway.
Zhao C, Chen H, Liang H, Zhao X, Tang W, Wei M, Li Y, Zhang J, Yu X, Chen G, Zhu H, Jiang L, Zhang X
Frontiers in pharmacology 2022;13:832245
Frontiers in pharmacology 2022;13:832245
Asiatic Acid Attenuates Osteoporotic Bone Loss in Ovariectomized Mice Through Inhibiting NF-kappaB/MAPK/ Protein Kinase B Signaling Pathway.
Dong M, Zeng J, Yang C, Qiu Y, Wang X
Frontiers in pharmacology 2022;13:829741
Frontiers in pharmacology 2022;13:829741
ALG-bFGF Hydrogel Inhibiting Autophagy Contributes to Protection of Blood-Spinal Cord Barrier Integrity via PI3K/Akt/FOXO1/KLF4 Pathway After SCI.
Zhang R, Xie L, Wu F, Xu J, Lu L, Cao L, Li L, Meng W, Zhang H, Shao C, Li X, Chen D
Frontiers in pharmacology 2022;13:828896
Frontiers in pharmacology 2022;13:828896
Trilobatin, a Natural Food Additive, Exerts Anti-Type 2 Diabetes Effect Mediated by Nrf2/ARE and IRS-1/GLUT2 Signaling Pathways.
Shi YL, Zhang YP, Luo H, Xu F, Gao JM, Shi JS, Gong QH
Frontiers in pharmacology 2022;13:828473
Frontiers in pharmacology 2022;13:828473
Recovery Infectious Enterovirus 71 by Bac-to-Bac Expression System in vitro and in vivo.
Lu B, Tang Q, Wang Q, Liu X, Peng H, Zhu B, Xie L, Li Z, Wang H, Zheng Z, Wang L, Li B
Frontiers in microbiology 2022;13:825111
Frontiers in microbiology 2022;13:825111
An RRx-001 Analogue With Potent Anti-NLRP3 Inflammasome Activity but Without High-Energy Nitro Functional Groups.
Lin H, Yang M, Li C, Lin B, Deng X, He H, Zhou R
Frontiers in pharmacology 2022;13:822833
Frontiers in pharmacology 2022;13:822833
Cold Exposure Induces Intestinal Barrier Damage and Endoplasmic Reticulum Stress in the Colon via the SIRT1/Nrf2 Signaling Pathway.
Guo J, Hu H, Chen Z, Xu J, Nie J, Lu J, Ma L, Ji H, Yuan J, Xu B
Frontiers in physiology 2022;13:822348
Frontiers in physiology 2022;13:822348
Characterization of a Novel Monoclonal Antibody for Serine-129 Phosphorylated α-Synuclein: A Potential Application for Clinical and Basic Research.
Liu W, Zhang Q, Xing H, Gao G, Liu J, Huang Y, Yang H
Frontiers in neurology 2022;13:821792
Frontiers in neurology 2022;13:821792
Gut microbiota-mediated metabolic restructuring aggravates emotional deficits after anesthesia/surgery in rats with preoperative stress.
Lei L, Ji M, Yang J, Chen S, Gu H, Yang JJ
Frontiers in immunology 2022;13:819289
Frontiers in immunology 2022;13:819289
Propofol Augments Paclitaxel-Induced Cervical Cancer Cell Ferroptosis In Vitro.
Zhao MY, Liu P, Sun C, Pei LJ, Huang YG
Frontiers in pharmacology 2022;13:816432
Frontiers in pharmacology 2022;13:816432
Metabolomics Analysis of the Prefrontal Cortex in a Rat Chronic Unpredictable Mild Stress Model of Depression.
Duan L, Fan R, Li T, Yang Z, Hu E, Yu Z, Tian J, Luo W, Zhang C
Frontiers in psychiatry 2022;13:815211
Frontiers in psychiatry 2022;13:815211
OPN5 Regulating Mechanism of Follicle Development Through the TSH-DIO2/DIO3 Pathway in Mountain Ducks Under Different Photoperiods.
Liufu S, Pan J, Sun J, Shen X, Jiang D, Ouyang H, Xu D, Tian Y, Huang Y
Frontiers in physiology 2022;13:813881
Frontiers in physiology 2022;13:813881
The Role of RNA-Binding Protein HuR in Lung Cancer by RNA Sequencing Analysis.
Ye X, Fu Q, Xiao H
Frontiers in genetics 2022;13:813268
Frontiers in genetics 2022;13:813268
Salidroside Ameliorates Depression by Suppressing NLRP3-Mediated Pyroptosis via P2X7/NF-κB/NLRP3 Signaling Pathway.
Chai Y, Cai Y, Fu Y, Wang Y, Zhang Y, Zhang X, Zhu L, Miao M, Yan T
Frontiers in pharmacology 2022;13:812362
Frontiers in pharmacology 2022;13:812362
Uncovering the Pharmacological Mechanisms of Gexia-Zhuyu Formula (GXZY) in Treating Liver Cirrhosis by an Integrative Pharmacology Strategy.
Cao X, Liang Y, Liu R, Zao X, Zhang J, Chen G, Liu R, Chen H, He Y, Zhang J, Ye Y
Frontiers in pharmacology 2022;13:793888
Frontiers in pharmacology 2022;13:793888
RNA 2'-O-Methyltransferase Fibrillarin Facilitates Virus Entry Into Macrophages Through Inhibiting Type I Interferon Response.
Li P, Liu Y, Song R, Zhao L, Yang J, Lu F, Cao X
Frontiers in immunology 2022;13:793582
Frontiers in immunology 2022;13:793582
Molecular Mechanisms Underlying the Inhibition of Proliferation and Differentiation by Florfenicol in P19 Stem Cells: Transcriptome Analysis.
Hu D, Zhang B, Suo Y, Li Z, Wan Z, Zhao W, Chen L, Yin Z, Ning H, Ge Y, Li W
Frontiers in pharmacology 2022;13:779664
Frontiers in pharmacology 2022;13:779664
Cinnamaldehyde Suppressed EGF-Induced EMT Process and Inhibits Ovarian Cancer Progression Through PI3K/AKT Pathway.
Wang Y, Li Y, Wang L, Chen B, Zhu M, Ma C, Mu C, Tao A, Li S, Luo L, Ma P, Ji S, Lan T
Frontiers in pharmacology 2022;13:779608
Frontiers in pharmacology 2022;13:779608
The Antitumor Effect and Mechanism of Total Flavonoids From Coreopsis Tinctoria Nutt (Snow Chrysanthemum) on Lung Cancer Using Network Pharmacology and Molecular Docking.
Wufuer Y, Yang X, Guo L, Aximujiang K, Zhong L, Yunusi K, Wu G
Frontiers in pharmacology 2022;13:761785
Frontiers in pharmacology 2022;13:761785
Inflammatory-Dependent Bidirectional Effect of Bile Acids on NLRP3 Inflammasome and Its Role in Ameliorating CPT-11-Induced Colitis.
Liao C, Wang D, Qin S, Zhang Y, Chen J, Xu R, Xu F, Zhang P
Frontiers in pharmacology 2022;13:677738
Frontiers in pharmacology 2022;13:677738
Astragalus propinquus schischkin and Salvia miltiorrhiza bunge promote angiogenesis to treat myocardial ischemia via Ang-1/Tie-2/FAK pathway.
Zhang MX, Huang XY, Song Y, Xu WL, Li YL, Li C
Frontiers in pharmacology 2022;13:1103557
Frontiers in pharmacology 2022;13:1103557
Deleterious variants in TAF7L cause human oligoasthenoteratozoospermia and its impairing histone to protamine exchange inducing reduced in vitro fertilization.
Bai H, Sha Y, Tan Y, Li P, Zhang Y, Xu J, Xu S, Ji Z, Wang X, Chen W, Zhang J, Yao C, Li Z, Zhi E
Frontiers in endocrinology 2022;13:1099270
Frontiers in endocrinology 2022;13:1099270
Wogonin increases gemcitabine sensitivity in pancreatic cancer by inhibiting Akt pathway.
Zhang T, Liu M, Liu Q, Xiao GG
Frontiers in pharmacology 2022;13:1068855
Frontiers in pharmacology 2022;13:1068855
Neuregulin-1β increases glucose uptake and promotes GLUT4 translocation in palmitate-treated C2C12 myotubes by activating PI3K/AKT signaling pathway.
Yu M, Wu S, Gong C, Chen L
Frontiers in pharmacology 2022;13:1066279
Frontiers in pharmacology 2022;13:1066279
Calycosin induces autophagy and apoptosis via Sestrin2/AMPK/mTOR in human papillary thyroid cancer cells.
Qu N, Qu J, Huang N, Zhang K, Ye T, Shi J, Chen B, Kan C, Zhang J, Han F, Hou N, Sun X, Pan R
Frontiers in pharmacology 2022;13:1056687
Frontiers in pharmacology 2022;13:1056687
Integrated network pharmacology and serum metabolomics approach deciphers the anti-colon cancer mechanisms of Huangqi Guizhi Wuwu Decoction.
Pan B, Xia Y, Fang S, Ai J, Wang K, Zhang J, Du C, Chen Y, Liu L, Yan S
Frontiers in pharmacology 2022;13:1043252
Frontiers in pharmacology 2022;13:1043252
Sleeve gastrectomy improves lipid dysmetabolism by downregulating the USP20-HSPA2 axis in diet-induced obese mice.
Zhang W, Shi B, Li S, Liu Z, Li S, Dong S, Cheng Y, Zhu J, Zhang G, Zhong M
Frontiers in endocrinology 2022;13:1041027
Frontiers in endocrinology 2022;13:1041027
Pathophysiological conditions induced by SARS-CoV-2 infection reduce ACE2 expression in the lung.
Miura Y, Ohkubo H, Nakano A, Bourke JE, Kanazawa S
Frontiers in immunology 2022;13:1028613
Frontiers in immunology 2022;13:1028613
Protein-protein interactions between RUNX3 and ZEB1 in chronic lung injury induced by methamphetamine abuse.
Bao N, Cheng L, Wang Y, Peng Z, Wang Z, Chen S
Frontiers in pharmacology 2022;13:1025922
Frontiers in pharmacology 2022;13:1025922
Enterovirus 71 non-structural protein 3A hijacks vacuolar protein sorting 25 to boost exosome biogenesis to facilitate viral replication.
Ruan Z, Liang Y, Chen Z, Yin J, Li C, Pan P, Zhang Q, Wu J, Luo Z
Frontiers in microbiology 2022;13:1024899
Frontiers in microbiology 2022;13:1024899
Forsythiaside B ameliorates coagulopathies in a rat model of sepsis through inhibition of the formation of PAD4-dependent neutrophil extracellular traps.
He W, Xi Q, Cui H, Zhang P, Huang R, Wang T, Wang D
Frontiers in pharmacology 2022;13:1022985
Frontiers in pharmacology 2022;13:1022985
Improvement of gut-vascular barrier by terlipressin reduces bacterial translocation and remote organ injuries in gut-derived sepsis.
Chang Z, Zhang Y, Lin M, Wen S, Lai H, Zhan Y, Zhu X, Huang Z, Zhang X, Liu Z
Frontiers in pharmacology 2022;13:1019109
Frontiers in pharmacology 2022;13:1019109
Sleeve gastrectomy attenuated diabetes-related cognitive decline in diabetic rats.
Ding H, Liu C, Zhang S, Li B, Xu Q, Shi B, Li S, Dong S, Ma X, Zhang Y, Zhong M, Zhang G
Frontiers in endocrinology 2022;13:1015819
Frontiers in endocrinology 2022;13:1015819
Exploitation of tumor antigens and construction of immune subtype classifier for mRNA vaccine development in bladder cancer.
Zhang X, Zhang Y, Zhao L, Wang J, Li J, Wang X, Zhang M, Hu X
Frontiers in immunology 2022;13:1014638
Frontiers in immunology 2022;13:1014638
Clinical identification of expressed proteins in adrenal medullary hyperplasia detected with hypertension.
Ma H, Wang K, Lai B, Zhang X, Lv Y, Li R
Frontiers in endocrinology 2022;13:1014366
Frontiers in endocrinology 2022;13:1014366
Dual immunological and proliferative regulation of immune checkpoint FGL1 in lung adenocarcinoma: The pivotal role of the YY1-FGL1-MYH9 axis.
Tang XY, Xiong YL, Zhao YB, Yang J, Shi AP, Zheng KF, Liu YJ, Shu C, Jiang T, Ma N, Zhao JB
Frontiers in immunology 2022;13:1014053
Frontiers in immunology 2022;13:1014053
X-box binding protein 1: A new metabolic mediator and drug target of metformin?
Lou K, Sun P, Zhang C, Jiang Q, Pang S
Frontiers in pharmacology 2022;13:1013218
Frontiers in pharmacology 2022;13:1013218
Sunitinib induced hepatotoxicity in L02 cells via ROS-MAPKs signaling pathway.
Tang TL, Yang Y, Guo L, Xia S, Zhang B, Yan M
Frontiers in pharmacology 2022;13:1002142
Frontiers in pharmacology 2022;13:1002142
COA3 overexpression promotes non-small cell lung cancer metastasis by reprogramming glucose metabolism.
Lin H, Gao Y, Sun K, Zhang Q, Li Y, Chen M, Jin F
American journal of cancer research 2022;12(8):3662-3678
American journal of cancer research 2022;12(8):3662-3678
M2 microglia-derived extracellular vesicles promote white matter repair and functional recovery via miR-23a-5p after cerebral ischemia in mice.
Li Y, Liu Z, Song Y, Pan JJ, Jiang Y, Shi X, Liu C, Ma Y, Luo L, Mamtilahun M, Shi Z, Khan H, Xie Q, Wang Y, Tang Y, Zhang Z, Yang GY
Theranostics 2022;12(7):3553-3573
Theranostics 2022;12(7):3553-3573
miR-1297 inhibits osteosarcoma cell proliferation and growth by targeting CCND2.
Jiang P, Mao L, Lei X, Luo C, Zhang Y, Zhong X, Yin Z, Xu X, Li D, Zheng Q
American journal of cancer research 2022;12(7):3464-3478
American journal of cancer research 2022;12(7):3464-3478
Hepatic RACK1 deficiency protects against fulminant hepatitis through myeloid-derived suppressor cells.
Liu G, Wang Q, Deng L, Huang X, Yang G, Cheng Q, Guo T, Guo L, Niu C, Yang X, Dong J, Zhang J
Theranostics 2022;12(5):2248-2265
Theranostics 2022;12(5):2248-2265
Exosome-mediated delivery of RBP-J decoy oligodeoxynucleotides ameliorates hepatic fibrosis in mice.
He F, Li WN, Li XX, Yue KY, Duan JL, Ruan B, Liu JJ, Song P, Yue ZS, Tao KS, Wang L
Theranostics 2022;12(4):1816-1828
Theranostics 2022;12(4):1816-1828
Mitochondrial STAT3 exacerbates LPS-induced sepsis by driving CPT1a-mediated fatty acid oxidation.
Li R, Li X, Zhao J, Meng F, Yao C, Bao E, Sun N, Chen X, Cheng W, Hua H, Li X, Wang B, Wang H, Pan X, You H, Yang J, Ikezoe T
Theranostics 2022;12(2):976-998
Theranostics 2022;12(2):976-998
Methionine deprivation inhibits glioma growth through downregulation of CTSL.
Qian F, Xu H, Zhang Y, Li L, Yu R
American journal of cancer research 2022;12(11):5004-5018
American journal of cancer research 2022;12(11):5004-5018
Integrative proteomics and m6A microarray analyses of the signatures induced by METTL3 reveals prognostically significant in gastric cancer by affecting cellular metabolism.
Peng G, Chen S, Zheng N, Tang Y, Su X, Wang J, Dong R, Wu D, Hu M, Zhao Y, Liu M, Wu H
Frontiers in oncology 2022;12:996329
Frontiers in oncology 2022;12:996329
Identification of pyroptosis-related lncRNA signature and AC005253.1 as a pyroptosis-related oncogene in prostate cancer.
Yu J, Tang R, Li J
Frontiers in oncology 2022;12:991165
Frontiers in oncology 2022;12:991165
FTO promotes liver inflammation by suppressing m6A mRNA methylation of IL-17RA.
Gan X, Dai Z, Ge C, Yin H, Wang Y, Tan J, Sun S, Zhou W, Yuan S, Yang F
Frontiers in oncology 2022;12:989353
Frontiers in oncology 2022;12:989353
Construction and validation of a prognostic model with RNA binding protein-related mRNAs for the HBV-related hepatocellular carcinoma patients.
Xu S, Liu H, Tian R, Xie J, Chen S, Luo J, Zhu H, Wang Y, Li Z
Frontiers in oncology 2022;12:970613
Frontiers in oncology 2022;12:970613
Effects of glycolysis and polyamine predation on intestinal epithelial barrier in colorectal cancer.
Wang Y, He H, Chen J, Song Z, Pan X, Lan T, Wang G
Frontiers in oncology 2022;12:961257
Frontiers in oncology 2022;12:961257
Pan-cancer analysis reveals DDX21 as a potential biomarker for the prognosis of multiple tumor types.
Hu A, Wang Y, Tian J, Chen Z, Chen R, Han X, Chen Y, Liu T, Chen Q
Frontiers in oncology 2022;12:947054
Frontiers in oncology 2022;12:947054
Silenced LINC01134 Enhances Oxaliplatin Sensitivity by Facilitating Ferroptosis Through GPX4 in Hepatocarcinoma.
Kang X, Huo Y, Jia S, He F, Li H, Zhou Q, Chang N, Liu D, Li R, Hu Y, Zhang P, Xu A
Frontiers in oncology 2022;12:939605
Frontiers in oncology 2022;12:939605
CAPRIN2 upregulation by LINC00941 promotes nasopharyngeal carcinoma ferroptosis resistance and metastatic colonization through HMGCR.
Qiu L, Zhou R, Zhou L, Yang S, Wu J
Frontiers in oncology 2022;12:931749
Frontiers in oncology 2022;12:931749
Loss of exosomal micro-RNA-200b-3p from hypoxia cancer-associated fibroblasts reduces sensitivity to 5-flourouracil in colorectal cancer through targeting high-mobility group box 3.
Yuan H, Chen B, Chai R, Gong W, Wan Z, Zheng B, Hu X, Guo Y, Gao S, Dai Q, Yu P, Tu S
Frontiers in oncology 2022;12:920131
Frontiers in oncology 2022;12:920131
ESR1 Regulates the Obesity- and Metabolism-Differential Gene MMAA to Inhibit the Occurrence and Development of Hepatocellular Carcinoma.
Zhang Y, Cheng J, Zhong C, Xia Q, Li Y, Chen P, Fan X, Mao Q, Lin H, Hong D
Frontiers in oncology 2022;12:899969
Frontiers in oncology 2022;12:899969
High-Metastatic Melanoma Cells Promote the Metastatic Capability of Low-Metastatic Melanoma Cells via Exosomal Transfer of miR-411-5p.
Chen H, Zeng B, Li X, Zhao Q, Liu D, Chen Y, Zhang Y, Wang J, Xing HR
Frontiers in oncology 2022;12:895164
Frontiers in oncology 2022;12:895164
ITGB5 promotes innate radiation resistance in pancreatic adenocarcinoma by promoting DNA damage repair and the MEK/ERK signaling pathway.
Wen X, Chen S, Chen X, Qiu H, Wang W, Zhang N, Liu W, Wang T, Ding X, Zhang L
Frontiers in oncology 2022;12:887068
Frontiers in oncology 2022;12:887068
TFAP2C-Mediated lncRNA PCAT1 Inhibits Ferroptosis in Docetaxel-Resistant Prostate Cancer Through c-Myc/miR-25-3p/SLC7A11 Signaling.
Jiang X, Guo S, Xu M, Ma B, Liu R, Xu Y, Zhang Y
Frontiers in oncology 2022;12:862015
Frontiers in oncology 2022;12:862015
Mitochondrion-Localized SND1 Promotes Mitophagy and Liver Cancer Progression Through PGAM5.
Liang S, Zhu C, Suo C, Wei H, Yu Y, Gu X, Chen L, Yuan M, Shen S, Li S, Sun L, Gao P
Frontiers in oncology 2022;12:857968
Frontiers in oncology 2022;12:857968
Up-Regulation of TRIM32 Associated With the Poor Prognosis of Acute Myeloid Leukemia by Integrated Bioinformatics Analysis With External Validation.
Xu X, Qi J, Yang J, Pan T, Han H, Yang M, Han Y
Frontiers in oncology 2022;12:848395
Frontiers in oncology 2022;12:848395
FGF19 Is Coamplified With CCND1 to Promote Proliferation in Lung Squamous Cell Carcinoma and Their Combined Inhibition Shows Improved Efficacy.
Zhang Y, Wu T, Li F, Cheng Y, Han Q, Lu X, Lu S, Xia W
Frontiers in oncology 2022;12:846744
Frontiers in oncology 2022;12:846744
Knockdown of hnRNPA1 Promotes NSCLC Metastasis and EMT by Regulating Alternative Splicing of LAS1L exon 9.
Han P, Cao P, Yue J, Kong K, Hu S, Deng Y, Li L, Li F, Zhao B
Frontiers in oncology 2022;12:837248
Frontiers in oncology 2022;12:837248
Olaparib Induces RPL5/RPL11-Dependent p53 Activation via Nucleolar Stress.
Han T, Tong J, Wang M, Gan Y, Gao B, Chen J, Liu Y, Hao Q, Zhou X
Frontiers in oncology 2022;12:821366
Frontiers in oncology 2022;12:821366
Inhibition of NEK7 Suppressed Hepatocellular Carcinoma Progression by Mediating Cancer Cell Pyroptosis.
Yan Z, Da Q, Li Z, Lin Q, Yi J, Su Y, Yu G, Ren Q, Liu X, Lin Z, Qu J, Yin W, Liu J
Frontiers in oncology 2022;12:812655
Frontiers in oncology 2022;12:812655
Thymidine Kinase 1 Drives Skin Cutaneous Melanoma Malignant Progression and Metabolic Reprogramming.
Zuo S, Wang H, Li L, Pan H, Lu L
Frontiers in oncology 2022;12:802807
Frontiers in oncology 2022;12:802807
Syntenin Regulated by miR-216b Promotes Cancer Progression in Pancreatic Cancer.
Zu F, Chen H, Liu Q, Zang H, Li Z, Tan X
Frontiers in oncology 2022;12:790788
Frontiers in oncology 2022;12:790788
Overexpression of CDCA8 Predicts Poor Prognosis and Promotes Tumor Cell Growth in Prostate Cancer.
Wan S, He Y, Zhang B, Yang Z, Du FM, Zhang CP, Fu YQ, Mi J
Frontiers in oncology 2022;12:784183
Frontiers in oncology 2022;12:784183
Transient Receptor Potential Cation Channel Subfamily V Member 1 Expression Promotes Chemoresistance in Non-Small-Cell Lung Cancer.
Li L, Chen C, Xiang Q, Fan S, Xiao T, Chen Y, Zheng D
Frontiers in oncology 2022;12:773654
Frontiers in oncology 2022;12:773654
Anti-Tumor Role of CAMK2B in Remodeling the Stromal Microenvironment and Inhibiting Proliferation in Papillary Renal Cell Carcinoma.
Jia Q, Liao X, Zhang Y, Xu B, Song Y, Bian G, Fu X
Frontiers in oncology 2022;12:740051
Frontiers in oncology 2022;12:740051
Dual-fluorescent reporter for live-cell imaging of the ER during DENV infection.
Corliss L, Holliday M, Lennemann NJ
Frontiers in cellular and infection microbiology 2022;12:1042735
Frontiers in cellular and infection microbiology 2022;12:1042735
Inhibition of RNF182 mediated by Bap promotes non-small cell lung cancer progression.
Liu Y, Ouyang L, Mao C, Chen Y, Liu N, Chen L, Shi Y, Xiao D, Liu S, Tao Y
Frontiers in oncology 2022;12:1009508
Frontiers in oncology 2022;12:1009508
Polysaccharides from Vaccaria segetalis seeds reduce urinary tract infections by inhibiting the adhesion and invasion abilities of uropathogenic Escherichia coli.
Yao R, Mao X, Xu Y, Qiu X, Zhou L, Wang Y, Pang B, Chen M, Cao S, Bao L, Bao Y, Guo S, Hu L, Zhang H, Cui X
Frontiers in cellular and infection microbiology 2022;12:1004751
Frontiers in cellular and infection microbiology 2022;12:1004751
Retrospective analysis of the efficacy of adjuvant cytokine-induced killer cell immunotherapy combined with chemotherapy in colorectal cancer patients after surgery.
Li X, Zhou H, Huang W, Wang X, Meng M, Hou Z, Liao L, Tang W, Xie Y, Wang R, Yu H, Wang L, Zhu H, Wang W, Tan J, Li R
Clinical & translational immunology 2022;11(1):e1368
Clinical & translational immunology 2022;11(1):e1368
CAV1 alleviated CaOx stones formation via suppressing autophagy-dependent ferroptosis.
Yang Y, Hong S, Lu Y, Wang Q, Wang S, Xun Y
PeerJ 2022;10:e14033
PeerJ 2022;10:e14033
Involvement of PI3K/Akt signaling pathway in promoting osteogenesis on titanium implant surfaces modified with novel non-thermal atmospheric plasma.
Zheng Z, He Y, Long L, Gan S, Chen S, Zhang M, Xu J, Fu R, Liao Y, Zhu Z, Wang H, Chen W
Frontiers in bioengineering and biotechnology 2022;10:975840
Frontiers in bioengineering and biotechnology 2022;10:975840
Adhesive, injectable, and ROS-responsive hybrid polyvinyl alcohol (PVA) hydrogel co-delivers metformin and fibroblast growth factor 21 (FGF21) for enhanced diabetic wound repair.
Zhu H, Xu J, Zhao M, Luo H, Lin M, Luo Y, Li Y, He H, Wu J
Frontiers in bioengineering and biotechnology 2022;10:968078
Frontiers in bioengineering and biotechnology 2022;10:968078
Expression profiles of exosomal tRNA-derived fragments and their biological functions in lipomas.
Zhou Y, Tao D, Shao Z, Wang X, Xu J, Li Y, Li K
Frontiers in cell and developmental biology 2022;10:942133
Frontiers in cell and developmental biology 2022;10:942133
Manganese-Based Prussian Blue Nanocatalysts Suppress Non-Small Cell Lung Cancer Growth and Metastasis via Photothermal and Chemodynamic Therapy.
Fang D, Liu Z, Jin H, Huang X, Shi Y, Ben S
Frontiers in bioengineering and biotechnology 2022;10:939158
Frontiers in bioengineering and biotechnology 2022;10:939158
Extracellular vimentin is expressed at the rear of activated macrophage-like cells: Potential role in enhancement of migration and phagocytosis.
Thalla DG, Rajwar AC, Laurent AM, Becher JE, Kainka L, Lautenschläger F
Frontiers in cell and developmental biology 2022;10:891281
Frontiers in cell and developmental biology 2022;10:891281
The Apoptotic Resistance of BRCA1-Deficient Ovarian Cancer Cells is Mediated by cAMP.
Yue W, Ma J, Xiao Y, Wang P, Gu X, Xie B, Li M
Frontiers in cell and developmental biology 2022;10:889656
Frontiers in cell and developmental biology 2022;10:889656
The Maternal Microbiome Programs the m(6)A Epitranscriptome of the Mouse Fetal Brain and Intestine.
Xiao Z, Liu S, Li Z, Cui J, Wang H, Wang Z, Ren Q, Xia L, Wang Z, Li Y
Frontiers in cell and developmental biology 2022;10:882994
Frontiers in cell and developmental biology 2022;10:882994
Umbilical Cord Mesenchymal Stem Cells Ameliorate Kidney Injury in MRL/Ipr Mice Through the TGF-β1 Pathway.
Huang C, Meng M, Li S, Liu S, Li L, Su Y, Gao H, He S, Zhao Y, Zhang M, Hou Z, Wang W, Wang X
Frontiers in cell and developmental biology 2022;10:876054
Frontiers in cell and developmental biology 2022;10:876054
Reciprocal Regulation of Mitofusin 2-Mediated Mitophagy and Mitochondrial Fusion by Different PINK1 Phosphorylation Events.
Li J, Dang X, Franco A, Dorn GW 2nd
Frontiers in cell and developmental biology 2022;10:868465
Frontiers in cell and developmental biology 2022;10:868465
AZD5153, a Bivalent BRD4 Inhibitor, Suppresses Hepatocarcinogenesis by Altering BRD4 Chromosomal Landscape and Modulating the Transcriptome of HCC Cells.
Lin CH, Kuo JC, Li D, Koenig AB, Pan A, Yan P, Bai XF, Lee RJ, Ghoshal K
Frontiers in cell and developmental biology 2022;10:853652
Frontiers in cell and developmental biology 2022;10:853652
miR-381-3p Cooperated With Hes1 to Regulate the Proliferation and Differentiation of Retinal Progenitor Cells.
Wang J, Sun N, Ju Y, Ni N, Tang Z, Zhang D, Dai X, Chen M, Wang Y, Gu P, Ji J
Frontiers in cell and developmental biology 2022;10:853215
Frontiers in cell and developmental biology 2022;10:853215
Elucidating the Potential Mechanisms Underlying Distraction Spinal Cord Injury-Associated Neuroinflammation and Apoptosis.
Han B, Liang W, Hai Y, Liu Y, Chen Y, Ding H, Yang J, Yin P
Frontiers in cell and developmental biology 2022;10:839313
Frontiers in cell and developmental biology 2022;10:839313
Adenosine Kinase Inhibition Prevents Severe Acute Pancreatitis via Suppressing Inflammation and Acinar Cell Necroptosis.
Sun S, Han Y, Zhang C, Liu H, Wang B, Cao S, Yuan Q, Wei S, Chen Y
Frontiers in cell and developmental biology 2022;10:827714
Frontiers in cell and developmental biology 2022;10:827714
Inhibition of the NLRP3 Inflammasome Activation by Manoalide Ameliorates Experimental Autoimmune Encephalomyelitis Pathogenesis.
Li C, Lin H, He H, Ma M, Jiang W, Zhou R
Frontiers in cell and developmental biology 2022;10:822236
Frontiers in cell and developmental biology 2022;10:822236
PLK1 Mitigates Intervertebral Disc Degeneration by Delaying Senescence of Nucleus Pulposus Cells.
Zhang Z, Huang Y, Xu N, Wang J, Yao T, Xu Y, Qiao D, Gao J, Shen S, Ma J
Frontiers in cell and developmental biology 2022;10:819262
Frontiers in cell and developmental biology 2022;10:819262
Quercetin Administration Following Hypoxia-Induced Neonatal Brain Damage Attenuates Later-Life Seizure Susceptibility and Anxiety-Related Behavior: Modulating Inflammatory Response.
Wu Y, Wei H, Li P, Zhao H, Li R, Yang F
Frontiers in pediatrics 2022;10:791815
Frontiers in pediatrics 2022;10:791815
Platelet-rich plasma attenuates the severity of joint capsule fibrosis following post-traumatic joint contracture in rats.
Zhang Y, Wang Z, Zong C, Gu X, Fan S, Xu L, Cai B, Lu S
Frontiers in bioengineering and biotechnology 2022;10:1078527
Frontiers in bioengineering and biotechnology 2022;10:1078527
Construction and osteogenic effects of 3D-printed porous titanium alloy loaded with VEGF/BMP-2 shell-core microspheres in a sustained-release system.
Liu Z, Xu Z, Wang X, Zhang Y, Wu Y, Jiang D, Jia R
Frontiers in bioengineering and biotechnology 2022;10:1028278
Frontiers in bioengineering and biotechnology 2022;10:1028278
BCAT1 promotes lung adenocarcinoma progression through enhanced mitochondrial function and NF-κB pathway activation.
Yu M, Zhao Q, Li J, Xu F, Zhang Z, Liu Y, Dai L, Zhang B, Zhang J, Zhang J
Journal of Zhejiang University. Science. B 2022 Sept 15;23(9):760-769
Journal of Zhejiang University. Science. B 2022 Sept 15;23(9):760-769
The E3 Ligase TRIM4 Facilitates SET Ubiquitin-Mediated Degradation to Enhance ER-α Action in Breast Cancer.
Han D, Wang L, Long L, Su P, Luo D, Zhang H, Li Z, Chen B, Zhao W, Zhang N, Wang X, Liang Y, Li Y, Hu G, Yang Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Sep;9(25):e2201701
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Sep;9(25):e2201701
Icariside II suppresses the tumorigenesis and development of ovarian cancer by regulating miR-144-3p/IGF2R axis.
Yuan D, Guo T, Qian H, Ge H, Zhao Y, Huang A, Wang X, Cao X, Zhu D, He C, Yu H
Drug development research 2022 Sep;83(6):1383-1393
Drug development research 2022 Sep;83(6):1383-1393
Quercetin ameliorates salivary gland apoptosis and inflammation in primary Sjögren's syndrome through regulation of the leptin/OB-R signaling.
Chang L, Kong A, Guo Y, Zhang J, Sun Y, Chen P, Wang X
Drug development research 2022 Sep;83(6):1351-1361
Drug development research 2022 Sep;83(6):1351-1361
Carotenoid transporter CD36 expression depends on hypoxia-inducible factor-1α in mouse soleus muscles.
Kitakaze T, Sugihira T, Kameyama H, Maruchi A, Kobayashi Y, Harada N, Yamaji R
Journal of clinical biochemistry and nutrition 2022 Sep;71(2):112-121
Journal of clinical biochemistry and nutrition 2022 Sep;71(2):112-121
HSPA5 repressed ferroptosis to promote colorectal cancer development by maintaining GPX4 stability.
Wang R, Hua L, Ma P, Song Y, Min J, Guo Y, Yang C, Li J, Su H
Neoplasma 2022 Sep;69(5):1054-1069
Neoplasma 2022 Sep;69(5):1054-1069
Insulin Deficiency Increases Sirt2 Level in Streptozotocin-Treated Alzheimer's Disease-Like Mouse Model: Increased Sirt2 Induces Tau Phosphorylation Through ERK Activation.
Zhou C, Jung CG, Kim MJ, Watanabe A, Abdelhamid M, Taslima F, Michikawa M
Molecular neurobiology 2022 Sep;59(9):5408-5425
Molecular neurobiology 2022 Sep;59(9):5408-5425
Nav1.8 in keratinocytes contributes to ROS-mediated inflammation in inflammatory skin diseases.
Zhang Y, Li Y, Zhou L, Yuan X, Wang Y, Deng Q, Deng Z, Xu S, Wang Q, Xie H, Li J
Redox biology 2022 Sep;55:102427
Redox biology 2022 Sep;55:102427
A possible mechanism to the antidepressant-like effects of 20 (S)-protopanaxadiol based on its target protein 14-3-3 ζ.
Chen L, Li R, Chen F, Zhang H, Zhu Z, Xu S, Cheng Y, Zhao Y
Journal of ginseng research 2022 Sep;46(5):666-674
Journal of ginseng research 2022 Sep;46(5):666-674
KRAS-G12D mutation drives immune suppression and the primary resistance of anti-PD-1/PD-L1 immunotherapy in non-small cell lung cancer.
Liu C, Zheng S, Wang Z, Wang S, Wang X, Yang L, Xu H, Cao Z, Feng X, Xue Q, Wang Y, Sun N, He J
Cancer communications (London, England) 2022 Sep;42(9):828-847
Cancer communications (London, England) 2022 Sep;42(9):828-847
Serum-derived exosomes from SD rats induce inflammation in macrophages through the mTOR pathway.
Wang Y, Liu YP, Sun ZB, Deng WH, Yuan XY, Lei YD, Cai Y, Huang L, Zhang ZH
Journal of applied toxicology : JAT 2022 Sep;42(9):1524-1532
Journal of applied toxicology : JAT 2022 Sep;42(9):1524-1532
FumDSB can alleviate the inflammatory response induced by fumonisin B(1) in growing pigs.
Liu Q, Huang L, Cui Z, Qiao B, Li F, Wang C
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 2022 Sep;39(9):1619-1633
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 2022 Sep;39(9):1619-1633
Exosomal miR-7002-5p derived from highglucose-induced macrophages suppresses autophagy in tubular epithelial cells by targeting Atg9b.
Zhao J, Chen J, Zhu W, Qi XM, Wu YG
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Sep;36(9):e22501
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Sep;36(9):e22501
Androgen receptor splicing variant 7 (ARv7) promotes DNA damage response in prostate cancer cells.
Luo H, Liu Y, Li Y, Zhang C, Yu B, Shao C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Sep;36(9):e22495
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Sep;36(9):e22495
Trehalose improves palmitic acid-induced apoptosis of osteoblasts by regulating SIRT3-medicated autophagy via the AMPK/mTOR/ULK1 pathway.
Cao L, Zhou S, Qiu X, Qiu S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Sep;36(9):e22491
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Sep;36(9):e22491
A novel role of TCAIM: suppressing renal carcinoma growth and enhancing its sensitivity to sunitinib.
Ye Z, Ren C, Wang Q, Wang Y
The FEBS journal 2022 Sep;289(17):5259-5278
The FEBS journal 2022 Sep;289(17):5259-5278
Rare variants in GABRG2 associated with sleep-related hypermotor epilepsy.
Jiang YL, Song CG, Zhou HM, Feng B, Zhao JJ, Liu Y, Man YL, Han J, Liu SB, Jiang W
Journal of neurology 2022 Sep;269(9):4939-4954
Journal of neurology 2022 Sep;269(9):4939-4954
Identification of ferroptosis-related genes for the prediction of prognosis and chemotherapy benefit of gastric cancer.
Zheng JJ, Wang JP
European review for medical and pharmacological sciences 2022 Sep;26(18):6754-6763
European review for medical and pharmacological sciences 2022 Sep;26(18):6754-6763
Epigallocatechin-3-gallate attenuates myocardial fibrosis in diabetic rats by activating autophagy.
Jia Q, Yang R, Mehmood S, Li Y
Experimental biology and medicine (Maywood, N.J.) 2022 Sep;247(17):1591-1600
Experimental biology and medicine (Maywood, N.J.) 2022 Sep;247(17):1591-1600
Integrated analysis of ALK higher expression in human cancer and downregulation in LUAD using RNA molecular scissors.
Saifullah, Tsukahara T
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2022 Sep;24(9):1785-1799
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2022 Sep;24(9):1785-1799
Salvianolic Acid B Alleviates Myocardial Ischemia Injury by Suppressing NLRP3 Inflammasome Activation via SIRT1-AMPK-PGC-1α Signaling Pathway.
Li Q, Zuo Z, Pan Y, Zhang Q, Xu L, Jiang B
Cardiovascular toxicology 2022 Sep;22(9):842-857
Cardiovascular toxicology 2022 Sep;22(9):842-857
Inhibition of 8-oxoguanine DNA glycosylase (OGG1) expression suppresses polycystic ovarian syndrome via the NF-κB signaling pathway.
Xia J, Wu S, Wu G, Yang J
Reproductive biology 2022 Sep;22(3):100679
Reproductive biology 2022 Sep;22(3):100679
DI-3-n-butylphthalide mitigates stress-induced cognitive deficits in mice through inhibition of NLRP3-Mediated neuroinflammation.
Chen X, He JL, Liu XT, Zhao N, Geng F, Zhu MM, Liu GP, Ren QG
Neurobiology of stress 2022 Sep;20:100486
Neurobiology of stress 2022 Sep;20:100486
High-circulating gut microbiota-dependent metabolite trimethylamine N-oxide is associated with poor prognosis in pulmonary arterial hypertension.
Yang Y, Zeng Q, Gao J, Yang B, Zhou J, Li K, Li L, Wang A, Li X, Liu Z, Luo Q, Zhao Z, Liu B, Xue J, Jiang X, Konerman MC, Zheng L, Xiong C
European heart journal open 2022 Sep;2(5):oeac021
European heart journal open 2022 Sep;2(5):oeac021
Protective effects of fraxin on cerebral ischemia-reperfusion injury by mediating neuroinflammation and oxidative stress through PPAR-γ/NF-κB pathway.
Yao H, Zhao J, Song X
Brain research bulletin 2022 Sep;187:49-62
Brain research bulletin 2022 Sep;187:49-62
Transcranial focused ultrasound stimulation reduces vasogenic edema after middle cerebral artery occlusion in mice.
Deng LD, Qi L, Suo Q, Wu SJ, Mamtilahun M, Shi RB, Liu Z, Sun JF, Tang YH, Zhang ZJ, Yang GY, Wang JX
Neural regeneration research 2022 Sep;17(9):2058-2063
Neural regeneration research 2022 Sep;17(9):2058-2063
Urolithin A alleviates blood-brain barrier disruption and attenuates neuronal apoptosis following traumatic brain injury in mice.
Gong QY, Cai L, Jing Y, Wang W, Yang DX, Chen SW, Tian HL
Neural regeneration research 2022 Sep;17(9):2007-2013
Neural regeneration research 2022 Sep;17(9):2007-2013
Phospho-proteomics reveals that RSK signaling is required for proliferation of natural killer cells stimulated with IL-2 or IL-15.
MacMullan MA, Wang P, Graham NA
Cytokine 2022 Sep;157:155958
Cytokine 2022 Sep;157:155958
Effect of flavonoids from Rhizoma Drynariae on osteoporosis rats and osteocytes.
Jin H, Jiang N, Xu W, Zhang Z, Yang Y, Zhang J, Xu H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113379
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113379
Compromised glycolysis contributes to foot process fusion of podocytes in diabetic kidney disease: Role of ornithine catabolism.
Luo Q, Liang W, Zhang Z, Zhu Z, Chen Z, Hu J, Yang K, Chi Q, Ding G
Metabolism: clinical and experimental 2022 Sep;134:155245
Metabolism: clinical and experimental 2022 Sep;134:155245
NF-κB-coupled IL17 mediates inflammatory signaling and intestinal inflammation in Artemia sinica.
Wang Z, Sun X, Wang W, Zheng M, Zhang D, Yin H
Fish & shellfish immunology 2022 Sep;128:38-49
Fish & shellfish immunology 2022 Sep;128:38-49
LncRNA DACH1 protects against pulmonary fibrosis by binding to SRSF1 to suppress CTNNB1 accumulation.
Sun J, Jin T, Niu Z, Guo J, Guo Y, Yang R, Wang Q, Gao H, Zhang Y, Li T, He W, Li Z, Ma W, Su W, Li L, Fan X, Shan H, Liang H
Acta pharmaceutica Sinica. B 2022 Sep;12(9):3602-3617
Acta pharmaceutica Sinica. B 2022 Sep;12(9):3602-3617
The ubiquitin-26S proteasome system and autophagy relay proteome homeostasis regulation during silique development.
Yu P, Hua Z
The Plant journal : for cell and molecular biology 2022 Sep;111(5):1324-1339
The Plant journal : for cell and molecular biology 2022 Sep;111(5):1324-1339
7-O-(2- (Propylamino)-2-oxoethyl) hesperetin attenuates inflammation and protects against alcoholic liver injury by NLRP12.
Niu XN, Zhang YL, Cheng M, Yin NN, Wu YY, Shi W, Yang YL, Zhu L, Huang C, Li J
International immunopharmacology 2022 Sep;110:109006
International immunopharmacology 2022 Sep;110:109006
Hirudin alleviates acute ischemic stroke by inhibiting NLRP3 inflammasome-mediated neuroinflammation: In vivo and in vitro approaches.
Li WQ, Qin ZS, Chen S, Cheng D, Yang SC, Choi YMM, Chu B, Zhou WH, Zhang ZJ
International immunopharmacology 2022 Sep;110:108967
International immunopharmacology 2022 Sep;110:108967
High expression of PTGES3 is an independent predictive poor prognostic biomarker and correlates with immune infiltrates in lung adenocarcinoma.
Gao P, Zou K, Xiao L, Zhou H, Xu X, Zeng Z, Zhang W
International immunopharmacology 2022 Sep;110:108954
International immunopharmacology 2022 Sep;110:108954
Neobavaisoflavone inhibits allergic inflammatory responses by suppressing mast cell activation.
Liang R, Yuan Y, Bai Y, Liu X, Chen J, Jiang D, Meng D, Chen G, Li B, Zhou L, Guo W
International immunopharmacology 2022 Sep;110:108953
International immunopharmacology 2022 Sep;110:108953
Luteolin ameliorates hypoxia-induced pulmonary hypertension via regulating HIF-2α-Arg-NO axis and PI3K-AKT-eNOS-NO signaling pathway.
Ji L, Su S, Xin M, Zhang Z, Nan X, Li Z, Lu D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154329
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154329
Iristectorigenin A exerts novel protective properties against airway inflammation and mucus hypersecretion in OVA-induced asthmatic mice: Iristectorigenin A ameliorates asthma phenotype.
Wuniqiemu T, Teng F, Qin J, Lv Y, Nabijan M, Luo Q, Zhou Y, Cui J, Yi L, Tang W, Zhu X, Amangu, Wang S, Abduwaki M, Nurahmat M, Wei Y, Dong JC
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154252
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154252
Serum exosomal coronin 1A and dynamin 2 as neural tube defect biomarkers.
Wang Y, Ma L, Jia S, Liu D, Gu H, Wei X, Ma W, Luo W, Bai Y, Wang W, Yuan Z
Journal of molecular medicine (Berlin, Germany) 2022 Sep;100(9):1307-1319
Journal of molecular medicine (Berlin, Germany) 2022 Sep;100(9):1307-1319
Biomimetic cytomembrane-coated ZIF-8-loaded DMDD nanoparticle and sonodynamic co-therapy for cancer.
Zhao S, Chen M, Yu Z, Pham TTH, Mo S, He Y, Liang T, Cao W, Han C
Annals of translational medicine 2022 Sep;10(18):971
Annals of translational medicine 2022 Sep;10(18):971
Growth advantage of corrected hepatocytes in a juvenile model of methylmalonic acidemia following liver directed adeno-associated viral mediated nuclease-free genome editing.
Venturoni LE, Chandler RJ, Liao J, Hoffmann V, Ramesh N, Gordo S, Chau N, Venditti CP
Molecular genetics and metabolism 2022 Sep-Oct;137(1-2):1-8
Molecular genetics and metabolism 2022 Sep-Oct;137(1-2):1-8
Achyranthoside D (AD) improve intervertebral disc degeneration through affect the autophagy and the activation of PI3K/Akt/mTOR pathway.
Zhang C, Li Z, Li L, Li S, Yang L, Chen L, Zhang X, Yang S, Guo Y
Journal of orthopaedic surgery (Hong Kong) 2022 Sep-Dec;30(3):10225536221135474
Journal of orthopaedic surgery (Hong Kong) 2022 Sep-Dec;30(3):10225536221135474
Topoisomerase IIA in adult NSCs regulates SVZ neurogenesis by transcriptional activation of Usp37.
Qin S, Yuan Y, Huang X, Tan Z, Hu X, Liu H, Pu Y, Ding YQ, Su Z, He C
Nucleic acids research 2022 Sep 9;50(16):9319-9338
Nucleic acids research 2022 Sep 9;50(16):9319-9338
Integrative network analysis of circular RNAs reveals regulatory mechanisms for hepatic specification of human iPSC-derived endoderm.
Bai F, Duan J, Yang D, Lai X, Zhu X, He X, Hu A
Stem cell research & therapy 2022 Sep 8;13(1):468
Stem cell research & therapy 2022 Sep 8;13(1):468
Identification of a small-molecule RPL11 mimetic that inhibits tumor growth by targeting MDM2-p53 pathway.
Wang B, Gao J, Zhao Z, Zhong X, Cui H, Hou H, Zhang Y, Zheng J, Di J, Liu Y
Molecular medicine (Cambridge, Mass.) 2022 Sep 7;28(1):109
Molecular medicine (Cambridge, Mass.) 2022 Sep 7;28(1):109
Acid ceramidase targeting pyruvate kinase affected trypsinogen activation in acute pancreatitis.
Xiao J, Zeng W, Zhang P, Zhou Y, Fang Q
Molecular medicine (Cambridge, Mass.) 2022 Sep 6;28(1):106
Molecular medicine (Cambridge, Mass.) 2022 Sep 6;28(1):106
The histone modification reader ZCWPW1 promotes double-strand break repair by regulating cross-talk of histone modifications and chromatin accessibility at meiotic hotspots.
Yuan S, Huang T, Bao Z, Wang S, Wu X, Liu J, Liu H, Chen ZJ
Genome biology 2022 Sep 6;23(1):187
Genome biology 2022 Sep 6;23(1):187
TRIM46 aggravated high glucose-induced hyper permeability and inflammatory response in human retinal capillary endothelial cells by promoting IκBα ubiquitination.
Shen H, Gong Q, Zhang J, Wang H, Qiu Q, Zhang J, Luo D
Eye and vision (London, England) 2022 Sep 5;9(1):35
Eye and vision (London, England) 2022 Sep 5;9(1):35
Membrane-associated RING-CH protein (MARCH8) is a novel glycolysis repressor targeted by miR-32 in colorectal cancer.
Wang Z, Wang MM, Geng Y, Ye CY, Zang YS
Journal of translational medicine 2022 Sep 5;20(1):402
Journal of translational medicine 2022 Sep 5;20(1):402
The MBNL1/circNTRK2/PAX5 pathway regulates aerobic glycolysis in glioblastoma cells by encoding a novel protein NTRK2-243aa.
Zhao Y, Song J, Dong W, Liu X, Yang C, Wang D, Xue Y, Ruan X, Liu L, Wang P, Zhang M, Liu Y
Cell death & disease 2022 Sep 5;13(9):767
Cell death & disease 2022 Sep 5;13(9):767
CLDN4 promotes growth of acute myeloid leukemia cells via regulating AKT and ERK1/2 signaling.
Hao S, Yang C, Song P, Shi H, Zou Y, Chen M, Wu X, Yin Y, Yu Z, Zhu W, Li M
Biochemical and biophysical research communications 2022 Sep 3;619:137-143
Biochemical and biophysical research communications 2022 Sep 3;619:137-143
FOXD1 facilitates pancreatic cancer cell proliferation, invasion, and metastasis by regulating GLUT1-mediated aerobic glycolysis.
Cai K, Chen S, Zhu C, Li L, Yu C, He Z, Sun C
Cell death & disease 2022 Sep 3;13(9):765
Cell death & disease 2022 Sep 3;13(9):765
Inhibition of Mcl-1 Synergistically Enhances the Antileukemic Activity of Gilteritinib and MRX-2843 in Preclinical Models of FLT3-Mutated Acute Myeloid Leukemia.
Wu S, Edwards H, Wang D, Liu S, Qiao X, Carter J, Wang Y, Taub JW, Wang G, Ge Y
Cells 2022 Sep 3;11(17)
Cells 2022 Sep 3;11(17)
SPLUNC1 regulates LPS-induced progression of nasopharyngeal carcinoma and proliferation of myeloid-derived suppressor cells.
Tang L, Peng L, Liu H, Xiao T, Gu W, Yang H, Wang H, Chen P
Medical oncology (Northwood, London, England) 2022 Sep 29;39(12):214
Medical oncology (Northwood, London, England) 2022 Sep 29;39(12):214
Exosomal miR-22-3p from Mesenchymal Stem Cells Inhibits the Epithelial-Mesenchymal Transition (EMT) of Melanoma Cells by Regulating LGALS1.
Chen Y, Fang Y, Li L, Luo H, Cao T, Tu B
Frontiers in bioscience (Landmark edition) 2022 Sep 29;27(9):275
Frontiers in bioscience (Landmark edition) 2022 Sep 29;27(9):275
Effects of growth hormone/estrogen/androgen on COVID-19-type proinflammatory responses in normal human lung epithelial BEAS-2B cells.
Zhu Z, Zhao Z, Chen X, Chu Z, He Y, Tan Y, Zhou J, Tang C
BMC molecular and cell biology 2022 Sep 29;23(1):42
BMC molecular and cell biology 2022 Sep 29;23(1):42
Grass Carp Prx 3 Elevates Host Antioxidant Activity and Induces Autophagy to Inhibit Grass Carp Reovirus (GCRV) Replication.
Liang X, Li Y, Chu P, Wang Q, Wang H, Liao L, Yang C, Zhu Z, Wang Y, He L
Antioxidants (Basel, Switzerland) 2022 Sep 29;11(10)
Antioxidants (Basel, Switzerland) 2022 Sep 29;11(10)
Rabphilin 3A binds the N-peptide of SNAP-25 to promote SNARE complex assembly in exocytosis.
Li T, Cheng Q, Wang S, Ma C
eLife 2022 Sep 29;11
eLife 2022 Sep 29;11
Nonstructural Protein 1 of Variant PEDV Plays a Key Role in Escaping Replication Restriction by Complement C3.
Fan B, Peng Q, Song S, Shi D, Zhang X, Guo W, Li Y, Zhou J, Zhu X, Zhao Y, Guo R, He K, Fan H, Ding S, Li B
Journal of virology 2022 Sep 28;96(18):e0102422
Journal of virology 2022 Sep 28;96(18):e0102422
Single cell analysis of PANoptosome cell death complexes through an expansion microscopy method.
Wang Y, Pandian N, Han JH, Sundaram B, Lee S, Karki R, Guy CS, Kanneganti TD
Cellular and molecular life sciences : CMLS 2022 Sep 28;79(10):531
Cellular and molecular life sciences : CMLS 2022 Sep 28;79(10):531
Post-Injury Buprenorphine Administration Is Associated with Long-Term Region-Specific Glial Alterations in Rats.
Ryu J, Jeizan P, Ahmed S, Ehsan S, Jose J, Regan S, Gorse K, Kelliher C, Lafrenaye A
Pharmaceutics 2022 Sep 28;14(10)
Pharmaceutics 2022 Sep 28;14(10)
Impad1 and Syt11 work in an epistatic pathway that regulates EMT-mediated vesicular trafficking to drive lung cancer invasion and metastasis.
Bajaj R, Rodriguez BL, Russell WK, Warner AN, Diao L, Wang J, Raso MG, Lu W, Khan K, Solis LS, Batra H, Tang X, Fradette JF, Kundu ST, Gibbons DL
Cell reports 2022 Sep 27;40(13):111429
Cell reports 2022 Sep 27;40(13):111429
Inhibiting ALK-TOPK signaling pathway promotes cell apoptosis of ALK-positive NSCLC.
Xiao J, Zhang L, Yi H, Zou L, Mo J, Xue F, Zheng J, Huang Y, Lu H, Wu H, Xue P, Zhang X, He L, Li Z, Pang S, Qiao G, Duan Q, Zhu F
Cell death & disease 2022 Sep 27;13(9):828
Cell death & disease 2022 Sep 27;13(9):828
Differential requirements for mitochondrial electron transport chain components in the adult murine liver.
Lesner NP, Wang X, Chen Z, Frank A, Menezes CJ, House S, Shelton SD, Lemoff A, McFadden DG, Wansapura J, DeBerardinis RJ, Mishra P
eLife 2022 Sep 26;11
eLife 2022 Sep 26;11
PIKE-A Modulates Mitochondrial Metabolism through Increasing SDHA Expression Mediated by STAT3/FTO Axis.
Sun M, Yan Q, Qiao Y, Zhao H, Wang Y, Shan C, Zhang S
International journal of molecular sciences 2022 Sep 25;23(19)
International journal of molecular sciences 2022 Sep 25;23(19)
Exploring Active Ingredients, Beneficial Effects, and Potential Mechanism of Allium tenuissimum L. Flower for Treating T2DM Mice Based on Network Pharmacology and Gut Microbiota.
Zhang SS, Hou YF, Liu SJ, Guo S, Ho CT, Bai NS
Nutrients 2022 Sep 25;14(19)
Nutrients 2022 Sep 25;14(19)
7-aminocephalosporanic acid, a novel HSP90β inhibitor, attenuates HFD-induced hepatic steatosis.
Zhang W, Xue H, Zhou C, Zheng Z, Xing M, Chu H, Li P, Zhang N, Dang Y, Xu X
Biochemical and biophysical research communications 2022 Sep 24;622:184-191
Biochemical and biophysical research communications 2022 Sep 24;622:184-191
Gastrodin Ameliorates Cognitive Dysfunction in Vascular Dementia Rats by Suppressing Ferroptosis via the Regulation of the Nrf2/Keap1-GPx4 Signaling Pathway.
Li Y, Zhang E, Yang H, Chen Y, Tao L, Xu Y, Chen T, Shen X
Molecules (Basel, Switzerland) 2022 Sep 24;27(19)
Molecules (Basel, Switzerland) 2022 Sep 24;27(19)
PKM2 promotes pulmonary fibrosis by stabilizing TGF-β1 receptor I and enhancing TGF-β1 signaling.
Gao S, Li X, Jiang Q, Liang Q, Zhang F, Li S, Zhang R, Luan J, Zhu J, Gu X, Xiao T, Huang H, Chen S, Ning W, Yang G, Yang C, Zhou H
Science advances 2022 Sep 23;8(38):eabo0987
Science advances 2022 Sep 23;8(38):eabo0987
Design, Synthesis, and Biological Evaluation of Androgen Receptor Degrading and Antagonizing Bifunctional Steroidal Analogs for the Treatment of Advanced Prostate Cancer.
Wang A, Luo X, Wang Y, Meng X, Lu Z, Yang Y
Journal of medicinal chemistry 2022 Sep 22;65(18):12460-12481
Journal of medicinal chemistry 2022 Sep 22;65(18):12460-12481
Akebia Saponin D Inhibits the Inflammatory Reaction by Inhibiting the IL-6-STAT3-DNMT3b Axis and Activating the Nrf2 Pathway.
Luo JF, Zhou H, Lio CK
Molecules (Basel, Switzerland) 2022 Sep 22;27(19)
Molecules (Basel, Switzerland) 2022 Sep 22;27(19)
TOP2A deficit-induced abnormal decidualization leads to recurrent implantation failure via the NF-κB signaling pathway.
Fu H, Tan W, Chen Z, Ye Z, Duan Y, Huang J, Qi H, Liu X
Reproductive biology and endocrinology : RB&E 2022 Sep 22;20(1):142
Reproductive biology and endocrinology : RB&E 2022 Sep 22;20(1):142
SHP-1/STAT3-Signaling-Axis-Regulated Coupling between BECN1 and SLC7A11 Contributes to Sorafenib-Induced Ferroptosis in Hepatocellular Carcinoma.
Huang CY, Chen LJ, Chen G, Chao TI, Wang CY
International journal of molecular sciences 2022 Sep 21;23(19)
International journal of molecular sciences 2022 Sep 21;23(19)
Correlation of the prognostic value of FNDC4 in glioblastoma with macrophage polarization.
Li H, Yan X, Ou S
Cancer cell international 2022 Sep 2;22(1):273
Cancer cell international 2022 Sep 2;22(1):273
A causal variant rs3769823 in 2q33.1 involved in apoptosis pathway leading to a decreased risk of non-small cell lung cancer.
Zhang X, Qin N, Fan J, Zhang C, Sun Q, Gu Y, Zhu M, Zhang E, Dai J, Jin G, Ma H, Hu Z, Shen H
Cancer biology & medicine 2022 Sep 2;19(9):1385-96
Cancer biology & medicine 2022 Sep 2;19(9):1385-96
KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer.
Yao H, Ren D, Wang Y, Wu L, Wu Y, Wang W, Li Q, Liu L
Cell death & disease 2022 Sep 2;13(9):761
Cell death & disease 2022 Sep 2;13(9):761
Asiatic Acid Attenuates Inflammation Induced by Salmonella via Upregulating LncRNA TVX1 in Microglia.
Zou W, Zhang J, Zhang K, Peng Z, Xin R, Wang L, Li J
International journal of molecular sciences 2022 Sep 19;23(18)
International journal of molecular sciences 2022 Sep 19;23(18)
TWIST1 induces proteasomal degradation of β-catenin during the differentiation of ovarian cancer stem-like cells.
Liu J, Shu G, Wu A, Zhang X, Zhou Z, Alvero AB, Mor G, Yin G
Scientific reports 2022 Sep 19;12(1):15650
Scientific reports 2022 Sep 19;12(1):15650
Isoalantolactone (IAL) Regulates Neuro-Inflammation and Neuronal Apoptosis to Curb Pathology of Parkinson's Disease.
He D, Liu Y, Li J, Wang H, Ye B, He Y, Li Z, Gao X, Fu S, Liu D
Cells 2022 Sep 19;11(18)
Cells 2022 Sep 19;11(18)
PD-1 Alleviates Cisplatin-Induced Muscle Atrophy by Regulating Inflammation and Oxidative Stress.
Liu X, Xu M, Yu Y, Chen Y, Weng X, Zhu L
Antioxidants (Basel, Switzerland) 2022 Sep 18;11(9)
Antioxidants (Basel, Switzerland) 2022 Sep 18;11(9)
CTCF DNA-binding domain undergoes dynamic and selective protein-protein interactions.
Zhou R, Tian K, Huang J, Duan W, Fu H, Feng Y, Wang H, Jiang Y, Li Y, Wang R, Hu J, Ma H, Qi Z, Ji X
iScience 2022 Sep 16;25(9):105011
iScience 2022 Sep 16;25(9):105011
Pericyte mediates the infiltration, migration, and polarization of macrophages by CD163/MCAM axis in glioblastoma.
Zhang H, Zhang N, Wu W, Wang Z, Dai Z, Liang X, Zhang L, Peng Y, Luo P, Zhang J, Liu Z, Cheng Q, Liu Z
iScience 2022 Sep 16;25(9):104918
iScience 2022 Sep 16;25(9):104918
Kaempferol impairs aerobic glycolysis against melanoma metastasis via inhibiting the mitochondrial binding of HK2 and VDAC1.
Zheng X, Pan Y, Yang G, Liu Y, Zou J, Zhao H, Yin G, Wu Y, Li X, Wei Z, Yu S, Zhao Y, Wang A, Chen W, Lu Y
European journal of pharmacology 2022 Sep 15;931:175226
European journal of pharmacology 2022 Sep 15;931:175226
Alpha1B-adreneroceptor is involved in norepinephrine-induced pulmonary artery smooth muscle cell proliferation via p38 signaling.
Xiao X, Zhang Y, Tian S, Wang X, Zhang Q, Zhang L, Yu X, Ma C, Zheng X, Li Y, Zhang J, Qu L
European journal of pharmacology 2022 Sep 15;931:175159
European journal of pharmacology 2022 Sep 15;931:175159
Aberrant human ClpP activation disturbs mitochondrial proteome homeostasis to suppress pancreatic ductal adenocarcinoma.
Wang P, Zhang T, Wang X, Xiao H, Li H, Zhou LL, Yang T, Wei B, Zhu Z, Zhou L, Yang S, Lu X, Zhang Y, Huang Y, Gan J, Yang CG
Cell chemical biology 2022 Sep 15;29(9):1396-1408.e8
Cell chemical biology 2022 Sep 15;29(9):1396-1408.e8
Purple sweet potato delphinidin-3-rutin represses glioma proliferation by inducing miR-20b-5p/Atg7-dependent cytostatic autophagy.
Wang M, Liu K, Bu H, Cong H, Dong G, Xu N, Li C, Zhao Y, Jiang F, Zhang Y, Yuan B, Li R, Jiang J
Molecular therapy oncolytics 2022 Sep 15;26:314-329
Molecular therapy oncolytics 2022 Sep 15;26:314-329
African Swine Fever Virus pI215L Inhibits Type I Interferon Signaling by Targeting Interferon Regulatory Factor 9 for Autophagic Degradation.
Li L, Fu J, Li J, Guo S, Chen Q, Zhang Y, Liu Z, Tan C, Chen H, Wang X
Journal of virology 2022 Sep 14;96(17):e0094422
Journal of virology 2022 Sep 14;96(17):e0094422
CIDEA Regulates De Novo Fatty Acid Synthesis in Bovine Mammary Epithelial Cells by Targeting the AMPK/PPARγ Axis and Regulating SREBP1.
Cheng J, Xu D, Chen L, Guo W, Hu G, Liu J, Fu S
Journal of agricultural and food chemistry 2022 Sep 14;70(36):11324-11335
Journal of agricultural and food chemistry 2022 Sep 14;70(36):11324-11335
Chemically modified in-vitro-transcribed mRNA encoding thrombopoietin stimulates thrombopoiesis in mice.
Zhang Y, Xi X, Yu H, Yang L, Lin J, Yang W, Liu J, Fan X, Xu Y
Molecular therapy. Nucleic acids 2022 Sep 13;29:657-671
Molecular therapy. Nucleic acids 2022 Sep 13;29:657-671
Deubiquitination of BES1 by UBP12/UBP13 promotes brassinosteroid signaling and plant growth.
Park SH, Jeong JS, Zhou Y, Binte Mustafa NF, Chua NH
Plant communications 2022 Sep 12;3(5):100348
Plant communications 2022 Sep 12;3(5):100348
Direct conversion of human umbilical cord mesenchymal stem cells into retinal pigment epithelial cells for treatment of retinal degeneration.
Zhu X, Chen Z, Wang L, Ou Q, Feng Z, Xiao H, Shen Q, Li Y, Jin C, Xu JY, Gao F, Wang J, Zhang J, Zhang J, Xu Z, Xu GT, Lu L, Tian H
Cell death & disease 2022 Sep 12;13(9):785
Cell death & disease 2022 Sep 12;13(9):785
GCAF(TMEM251) regulates lysosome biogenesis by activating the mannose-6-phosphate pathway.
Zhang W, Yang X, Li Y, Yu L, Zhang B, Zhang J, Cho WJ, Venkatarangan V, Chen L, Burugula BB, Bui S, Wang Y, Duan C, Kitzman JO, Li M
Nature communications 2022 Sep 12;13(1):5351
Nature communications 2022 Sep 12;13(1):5351
COPS5 Conferred the Platinum Resistance in Epithelial Ovarian Cancer.
Zhang H, Yan T, Zhong A, Guo L, Lu R
Current issues in molecular biology 2022 Sep 1;44(9):3948-3958
Current issues in molecular biology 2022 Sep 1;44(9):3948-3958
MCPIP1 promotes cell proliferation, migration and angiogenesis of glioma via VEGFA-mediated ERK pathway.
Wang R, Sun S, Wang Z, Xu X, Jiang T, Liu H, Li X, Ren Z
Experimental cell research 2022 Sep 1;418(1):113267
Experimental cell research 2022 Sep 1;418(1):113267
Flufenamic acid improves survival and neurologic outcome after successful cardiopulmonary resuscitation in mice.
Chen J, Chang Y, Zhu J, Peng Y, Li Z, Zhang K, Zhang Y, Lin C, Lin Z, Pan S, Huang K
Journal of neuroinflammation 2022 Sep 1;19(1):214
Journal of neuroinflammation 2022 Sep 1;19(1):214
Tumor-intrinsic PRC2 inactivation drives a context-dependent immune-desert microenvironment and is sensitized by immunogenic viruses.
Yan J, Chen Y, Patel AJ, Warda S, Lee CJ, Nixon BG, Wong EW, Miranda-Román MA, Yang N, Wang Y, Pachai MR, Sher J, Giff E, Tang F, Khurana E, Singer S, Liu Y, Galbo PM Jr, Maag JL, Koche RP, Zheng D, Antonescu CR, Deng L, Li MO, Chen Y, Chi P
The Journal of clinical investigation 2022 Sep 1;132(17)
The Journal of clinical investigation 2022 Sep 1;132(17)
Metabolism-Based Molecular Subtyping Endows Effective Ketogenic Therapy in p53-Mutant Colon Cancer.
Tang M, Xu H, Huang H, Kuang H, Wang C, Li Q, Zhang X, Ge Y, Song M, Zhang X, Wang Z, Ma C, Kang J, Zhang W, Wang Y, Zhang B, Zhang X, Chen Y, Cong M, Melino G, Wang X, Zhou F, Sun Q, Shi H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Oct;9(29):e2201992
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Oct;9(29):e2201992
TCQA, A Natural Caffeoylquinic Acid Derivative Attenuates H2O2-Induced Neuronal Apoptosis by Suppressing Phosphorylation of MAPKs Signaling Pathway.
Yang Y, Ding Y, Gao H, Jiang X, Zhao Q
Planta medica 2022 Oct;88(13):1132-1140
Planta medica 2022 Oct;88(13):1132-1140
Identification of active natural products that induce lysosomal biogenesis by lysosome-based screening and biological evaluation.
Ding X, Yang X, Zhao Y, Wang Y, Fei J, Niu Z, Dong X, Wang X, Liu B, Li H, Hao X, Zhao Y
Heliyon 2022 Oct;8(10):e11179
Heliyon 2022 Oct;8(10):e11179
Oleuropein ameliorated lung ischemia-reperfusion injury by inhibiting TLR4 signaling cascade in alveolar macrophages.
Xu Z, Sun X, Ding B, Zi M, Ma Y
Transplant immunology 2022 Oct;74:101664
Transplant immunology 2022 Oct;74:101664
EphA4 regulates white matter remyelination after ischemic stroke through Ephexin-1/RhoA/ROCK signaling pathway.
Liu C, Han S, Zheng J, Wang H, Li S, Li J
Glia 2022 Oct;70(10):1971-1991
Glia 2022 Oct;70(10):1971-1991
TCF3 protein was highly expressed in pediatric Burkitt lymphoma and predicts poor prognosis: a single-center study.
Man J, Wang H, Qian X, Chen L, Ma Y, Qian M, Zhai X
Leukemia & lymphoma 2022 Oct;63(10):2453-2460
Leukemia & lymphoma 2022 Oct;63(10):2453-2460
A Dual-Action Molecule Suppresses S. aureus Infection as an Inhibitor Targeting Hla Pore Formation and TLR2 Signaling.
Wang T, Jiang F, Su J, Chu X, Cao Y, Lv H, Deng X, Wang J
Advanced biology 2022 Oct;6(10):e2200109
Advanced biology 2022 Oct;6(10):e2200109
GDNF Promotes Astrocyte Abnormal Proliferation and Migration Through the GFRα1/RET/MAPK/pCREB/LOXL2 Signaling Axis.
Wang M, Han X, Zha W, Wang X, Liu L, Li Z, Shi Y, Kan X, Wang G, Gao D, Zhang B
Molecular neurobiology 2022 Oct;59(10):6321-6340
Molecular neurobiology 2022 Oct;59(10):6321-6340
Impact of Resolvin D1 on the inflammatory phenotype of periodontal ligament cell response to hypoxia.
Cai J, Liu J, Yan J, Lu X, Wang X, Li S, Mustafa K, Wang H, Xue Y, Mustafa M, Kantarci A, Xing Z
Journal of periodontal research 2022 Oct;57(5):1034-1042
Journal of periodontal research 2022 Oct;57(5):1034-1042
PGC-1α attenuates TNF-α-induced inflammatory responses in OCCM-30 cells.
Fu Y, Du M, Cao Z, He H
Journal of periodontal research 2022 Oct;57(5):1024-1033
Journal of periodontal research 2022 Oct;57(5):1024-1033
Quercetin in Tonglong Qibi decoction ameliorates testosterone-induced benign prostatic hyperplasia in rats by regulating Nrf2 signalling pathways and oxidative stress.
Fu W, Chen S, Zhang Z, Chen Y, You X, Li Q
Andrologia 2022 Oct;54(9):e14502
Andrologia 2022 Oct;54(9):e14502
The c.612A>G mutation of MC4R affects constitutive activity and signaling in domestic goats.
Yan Y, Chi S, Liu G, Huang Y, Pan D, Jiang X
Animal genetics 2022 Oct;53(5):665-675
Animal genetics 2022 Oct;53(5):665-675
Catalpol Exerts Antidepressant-Like Effects by Enhancing Anti-oxidation and Neurotrophy and Inhibiting Neuroinflammation via Activation of HO-1.
Wu X, Liu C, Wang J, Guan Y, Song L, Chen R, Gong M
Neurochemical research 2022 Oct;47(10):2975-2991
Neurochemical research 2022 Oct;47(10):2975-2991
Proteasomal deubiquitylase activity enhances cell surface recycling of the epidermal growth factor receptor in non-small cell lung cancer.
Wang S, Wang T, Yang Q, Cheng S, Liu F, Yang G, Wang F, Wang R, Yang D, Zhou M, Duan C, Zhang Y, Liu H, Dai Z, Tian K, Liu S
Cellular oncology (Dordrecht, Netherlands) 2022 Oct;45(5):951-965
Cellular oncology (Dordrecht, Netherlands) 2022 Oct;45(5):951-965
Effect of the Pulsed Electromagnetic Field Treatment in a Rat Model of Senile Osteoporosis In Vivo.
Zhou J, Wang J, Qu M, Huang X, Yin L, Liao Y, Huang F, Ning P, Zhong P, Zeng Y
Bioelectromagnetics 2022 Oct;43(7):438-447
Bioelectromagnetics 2022 Oct;43(7):438-447
Inducement of ER Stress by PAD Inhibitor BB-Cl-Amidine to Effectively Kill AML Cells.
Sun YN, Ma YN, Jia XQ, Yao Q, Chen JP, Li H
Current medical science 2022 Oct;42(5):958-965
Current medical science 2022 Oct;42(5):958-965
Network pharmacology and molecular docking study on the effect of Kaempferol in treatment of metabolic associated fatty liver disease.
Kaixuan Z, Dong Z, Huiwei B, Lijing LI
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Oct;42(5):788-794
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Oct;42(5):788-794
Ultrasound-based radiomics for the evaluation of fetal rat lung maturity: A noninvasive assessment method (Ultrasound-based radiomics in fetal rat lung).
Du Y, Jiao J, Cao A, Ji C, Li M, Ji C, Wu Y, Guo Y, Wang Y, Zhou J, Ren Y
Prenatal diagnosis 2022 Oct;42(11):1429-1437
Prenatal diagnosis 2022 Oct;42(11):1429-1437
Sestrin2 attenuates renal damage by regulating Hippo pathway in diabetic nephropathy.
Bian Y, Shi C, Song S, Mu L, Wu M, Qiu D, Dong J, Zhang W, Yuan C, Wang D, Zhou Z, Dong X, Shi Y
Cell and tissue research 2022 Oct;390(1):93-112
Cell and tissue research 2022 Oct;390(1):93-112
Hepatic cytokine-inducible SH2-containing protein (CISH) regulates gluconeogenesis via cAMP-responsive element binding protein (CREB).
Xiao F, Deng J, Jiao F, Hu X, Jiang H, Yuan F, Chen S, Niu Y, Jiang X, Guo F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Oct;36(10):e22541
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Oct;36(10):e22541
Bryodulcosigenin attenuates bleomycin-induced pulmonary fibrosis via inhibiting AMPK-mediated mesenchymal epithelial transition and oxidative stress.
Ding Y, Wang L, Liu B, Ren G, Okubo R, Yu J, Zhang C
Phytotherapy research : PTR 2022 Oct;36(10):3911-3923
Phytotherapy research : PTR 2022 Oct;36(10):3911-3923
MicroRNA-124 attenuates PTSD-like behaviors and reduces the level of inflammatory cytokines by downregulating the expression of TRAF6 in the hippocampus of rats following single-prolonged stress.
Chen Y, An Q, Yang ST, Chen YL, Tong L, Ji LL
Experimental neurology 2022 Oct;356:114154
Experimental neurology 2022 Oct;356:114154
Depression compromises antiviral innate immunity via the AVP-AHI1-Tyk2 axis.
Zhang HG, Wang B, Yang Y, Liu X, Wang J, Xin N, Li S, Miao Y, Wu Q, Guo T, Yuan Y, Zuo Y, Chen X, Ren T, Dong C, Wang J, Ruan H, Sun M, Xu X, Zheng H
Cell research 2022 Oct;32(10):897-913
Cell research 2022 Oct;32(10):897-913
Proteasomal degradation of WT proinsulin in pancreatic beta cells.
Xu X, Arunagiri A, Haataja L, Alam M, Ji S, Qi L, Tsai B, Liu M, Arvan P
The Journal of biological chemistry 2022 Oct;298(10):102406
The Journal of biological chemistry 2022 Oct;298(10):102406
Proto-oncogene FAM83A contributes to casein kinase 1-mediated mitochondrial maintenance and white adipocyte differentiation.
Huang K, Jia Z, Li H, Peng Y, Chen X, Luo N, Song T, Wang Y, Shi X, Kuang S, Yang G
The Journal of biological chemistry 2022 Oct;298(10):102339
The Journal of biological chemistry 2022 Oct;298(10):102339
ATG4B hinders porcine epidemic diarrhea virus replication through interacting with TRAF3 and activating type-I IFN signaling.
Dong S, Kong N, Qin W, Zhai H, Zhai X, Yang X, Ye C, Ye M, Liu C, Yu L, Zheng H, Tong W, Yu H, Zhang W, Li Y, Tong G, Shan T
Veterinary microbiology 2022 Oct;273:109544
Veterinary microbiology 2022 Oct;273:109544
IL-1β induced by PRRSV co-infection inhibited CSFV C-strain proliferation via the TLR4/NF-κB/MAPK pathways and the NLRP3 inflammasome.
Chen D, Xu S, Jiang R, Guo Y, Yang X, Zhang Y, Zhou L, Ge X, Han J, Guo X, Yang H
Veterinary microbiology 2022 Oct;273:109513
Veterinary microbiology 2022 Oct;273:109513
Pharmacologic inhibition of LAT1 predominantly suppresses transport of large neutral amino acids and downregulates global translation in cancer cells.
Nishikubo K, Ohgaki R, Okanishi H, Okuda S, Xu M, Endou H, Kanai Y
Journal of cellular and molecular medicine 2022 Oct;26(20):5246-5256
Journal of cellular and molecular medicine 2022 Oct;26(20):5246-5256
MiR-574-5p promotes cell proliferation by negatively regulating small C-terminal domain phosphatase 1 in esophageal squamous cell carcinoma.
Zhao C, Liu J, Xu Y, Guo J, Wang L, Chen L, Xu L, Dong G, Zheng W, Li Z, Cai H, Li S
Iranian journal of basic medical sciences 2022 Oct;25(10):1243-1250
Iranian journal of basic medical sciences 2022 Oct;25(10):1243-1250
Cold exposure-induced endoplasmic reticulum stress regulates autophagy through the SIRT2/FoxO1 signaling pathway.
Guo J, Nie J, Chen Z, Wang X, Hu H, Xu J, Lu J, Ma L, Ji H, Yuan J, Xu B
Journal of cellular physiology 2022 Oct;237(10):3960-3970
Journal of cellular physiology 2022 Oct;237(10):3960-3970
Inka2, a novel Pak4 inhibitor, regulates actin dynamics in neuronal development.
Yamada S, Mizukoshi T, Tokunaga A, Sakakibara SI
PLoS genetics 2022 Oct;18(10):e1010438
PLoS genetics 2022 Oct;18(10):e1010438
Schisantherin D from Schisandra chinensis (Turcz.) Baill. exhibits anti-liver fibrosis capacity via modulating ETBR involved signaling, an in vitro and in vivo study.
Li C, Ru YJ, Lin QY, Gao GC, Yang YD, Zhang XQ, Gao JL, Liu SH, Zheng CW, Wang L, Zheng YX, Wu JM
Fitoterapia 2022 Oct;162:105290
Fitoterapia 2022 Oct;162:105290
Apelin-13 attenuates depressive-like behaviors induced by chronic unpredictable mild stress via activating AMPK/PGC-1α/FNDC5/BDNF pathway.
Hu S, He L, Chen B, You Y
Peptides 2022 Oct;156:170847
Peptides 2022 Oct;156:170847
Babao Dan inhibits lymphangiogenesis of gastric cancer in vitro and in vivo via lncRNA-ANRIL/VEGF-C/VEGFR-3 signaling axis.
Guan J, Guan B, Shang H, Peng J, Yang H, Lin J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113630
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113630
Fucoidan inhibits EGFR redistribution and potentiates sorafenib to overcome sorafenib-resistant hepatocellular carcinoma.
Luo J, Li L, Zhu Z, Chang B, Deng F, Wang D, Lu X, Zuo D, Chen Q, Zhou J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113602
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113602
Gegen Qinlian decoction ameliorates murine colitis by inhibiting the expansion of Enterobacteriaceae through activating PPAR-γ signaling.
Hu J, Tong Y, Shen Z, Li Y, Cheng C, Au R, Xu F, Liu Y, Zhu L, Shen H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113571
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113571
Identification by RNA-Seq of let-7 clusters as prenatal biomarkers for nonsyndromic cleft lip with palate.
Jia S, Zhang Q, Wang Y, Wei X, Gu H, Liu D, Ma W, He Y, Luo W, Yuan Z
Annals of the New York Academy of Sciences 2022 Oct;1516(1):234-246
Annals of the New York Academy of Sciences 2022 Oct;1516(1):234-246
LncRNA LINC00281/Annexin A2 Regulates Vascular Smooth Muscle Cell Phenotype Switching via the Nuclear Factor-Kappa B Signaling Pathway.
Cheng L, Wang H, Maboh R, Mao G, Wu X, Chen H
Journal of cardiovascular translational research 2022 Oct;15(5):971-984
Journal of cardiovascular translational research 2022 Oct;15(5):971-984
Lithocarpus polystachyus (Sweet Tea) water extract promotes human hepatocytes HL7702 proliferation through activation of HGF/AKT/ERK signaling pathway.
Lei M, Chen N, Xu Y, Gong Q, Gao J
Chinese herbal medicines 2022 Oct;14(4):576-582
Chinese herbal medicines 2022 Oct;14(4):576-582
VCAM-1-binding peptide targeted cationic liposomes containing NLRP3 siRNA to modulate LDL transcytosis as a novel therapy for experimental atherosclerosis.
Jia X, Bai X, Yang X, Wang L, Lu Y, Zhu L, Zhao Y, Cheng W, Shu M, Mei Q, Jin S
Metabolism: clinical and experimental 2022 Oct;135:155274
Metabolism: clinical and experimental 2022 Oct;135:155274
Triclocarban evoked neutrophil extracellular trap formation in common carp (Cyprinus carpio L.) by modulating SIRT3-mediated ROS crosstalk with ERK1/2/p38 signaling.
Li S, Wang Y, Yu D, Zhang Y, Wang X, Shi M, Xiao Y, Li X, Xiao H, Chen L, Xiong X
Fish & shellfish immunology 2022 Oct;129:85-95
Fish & shellfish immunology 2022 Oct;129:85-95
Synthesis and anti-inflammatory activity of paeonol derivatives with etherized aryl urea by regulating TLR4/MyD88 signaling pathway in RAW264.7 cell.
Gong X, He Y, Yang D, Yang S, Li J, Zhao H, Chen Q, Ren Q, Zhang B
Bioorganic chemistry 2022 Oct;127:105939
Bioorganic chemistry 2022 Oct;127:105939
Hoxa9/meis1-transgenic zebrafish develops acute myeloid leukaemia-like disease with rapid onset and high penetrance.
Wang W, Li H, Huang M, Wang X, Li W, Qian X, Jing L
Open biology 2022 Oct;12(10):220172
Open biology 2022 Oct;12(10):220172
Acadesine alleviates acute pancreatitis-related lung injury by mediating the barrier protective function of pulmonary microvascular endothelial cells.
Zhu X, Duan F, Zhang Y, Wang X, Wang Y, Chen J, Zhang L, Wu M, Pan Z, Chen B
International immunopharmacology 2022 Oct;111:109165
International immunopharmacology 2022 Oct;111:109165
Eupalinolide B attenuates lipopolysaccharide-induced acute lung injury through inhibition of NF-κB and MAPKs signaling by targeting TAK1 protein.
Yang L, Chen H, Hu Q, Liu L, Yuan Y, Zhang C, Tang J, Shen X
International immunopharmacology 2022 Oct;111:109148
International immunopharmacology 2022 Oct;111:109148
SCO-spondin-derived peptide NX210 rescues neurons from cerebral ischemia/reperfusion injury through modulating the Integrin-β1 mediated PI3K/Akt pathway.
Yang L, Zhu J, Yang L, Gan Y, Hu D, Zhao J, Zhao Y
International immunopharmacology 2022 Oct;111:109079
International immunopharmacology 2022 Oct;111:109079
High-throughput membrane-anchored proteome screening reveals PIEZO1 as a promising antibody-drug target for human esophageal squamous cell carcinoma.
Qin X, Ni Z, Jiang J, Liu X, Dong X, Li M, Miao K, Rao S, Zhang W, Cai K
Cancer medicine 2022 Oct;11(19):3700-3713
Cancer medicine 2022 Oct;11(19):3700-3713
Ginseng under forest exerts stronger anti-aging effects compared to garden ginseng probably via regulating PI3K/AKT/mTOR pathway, SIRT1/NF-κB pathway and intestinal flora.
Hao M, Ding C, Peng X, Chen H, Dong L, Zhang Y, Chen X, Liu W, Luo Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Oct;105:154365
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Oct;105:154365
Ban-xia-xie-xin-tang ameliorates hepatic steatosis by regulating Cidea and Cidec expression in HFD-fed mice.
Xia QS, Gao Y, Wen-Bin W, Wu F, Dong H, Xu LJ, Fang K, Hu ML, Yuan F, Lu FE, Gong J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Oct;105:154351
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Oct;105:154351
Deletion of Smurf1 attenuates liver steatosis via stabilization of p53.
Lin W, Zhang X, Zhang C, Li L, Zhang J, Xie P, Zhan Y, An W
Laboratory investigation; a journal of technical methods and pathology 2022 Oct;102(10):1075-1087
Laboratory investigation; a journal of technical methods and pathology 2022 Oct;102(10):1075-1087
Structure-based discovery of Licoflavone B and Ginkgetin targeting c-Myc G-quadruplex to suppress c-Myc transcription and myeloma growth.
Liu L, Geng X, Zhang J, Li S, Gao J
Chemical biology & drug design 2022 Oct;100(4):525-533
Chemical biology & drug design 2022 Oct;100(4):525-533
Downregulation of exosomal miR-7-5p promotes breast cancer migration and invasion by targeting RYK and participating in the atypical WNT signalling pathway.
Liang Z, Liu L, Gao R, Che C, Yang G
Cellular & molecular biology letters 2022 Oct 9;27(1):88
Cellular & molecular biology letters 2022 Oct 9;27(1):88
CXCL12/CXCR7/β-arrestin1 biased signal promotes epithelial-to-mesenchymal transition of colorectal cancer by repressing miRNAs through YAP1 nuclear translocation.
Si M, Song Y, Wang X, Wang D, Liu X, Qu X, Song Z, Yu X
Cell & bioscience 2022 Oct 9;12(1):171
Cell & bioscience 2022 Oct 9;12(1):171
Up-regulation of miR-133a-3p promotes ovary insulin resistance on granulosa cells of obese PCOS patients via inhibiting PI3K/AKT signaling.
Yang X, Wang K, Lang J, Guo D, Gao H, Qiu Y, Jin X, Zhang M, Shi J, Ma Q, Ma Q, Wen Z
BMC women's health 2022 Oct 8;22(1):412
BMC women's health 2022 Oct 8;22(1):412
Gandouling Mitigates CuSO(4)-Induced Heart Injury in Rats.
Fang S, Yang W, Zhang K, Peng C
Animals : an open access journal from MDPI 2022 Oct 8;12(19)
Animals : an open access journal from MDPI 2022 Oct 8;12(19)
Progesterone Induces Apoptosis and Steroidogenesis in Porcine Placental Trophoblasts.
Liu Y, Ding H, Yang Y, Liu Y, Cao X, Feng T
Animals : an open access journal from MDPI 2022 Oct 8;12(19)
Animals : an open access journal from MDPI 2022 Oct 8;12(19)
ZIP1(+) fibroblasts protect lung cancer against chemotherapy via connexin-43 mediated intercellular Zn(2+) transfer.
Ni C, Lou X, Yao X, Wang L, Wan J, Duan X, Liang J, Zhang K, Yang Y, Zhang L, Sun C, Li Z, Wang M, Zhu L, Lv D, Qin Z
Nature communications 2022 Oct 7;13(1):5919
Nature communications 2022 Oct 7;13(1):5919
Protein disulfide isomerase blocks the interaction of LC3II-PHB2 and promotes mTOR signaling to regulate autophagy and radio/chemo-sensitivity.
Wang R, Shang Y, Chen B, Xu F, Zhang J, Zhang Z, Zhao X, Wan X, Xu A, Wu L, Zhao G
Cell death & disease 2022 Oct 6;13(10):851
Cell death & disease 2022 Oct 6;13(10):851
Exploring the protective mechanisms of total tannins from Geum japonicum var. chinense F.Bolle in mice with hematopoietic dysfunction via the JAK2/STAT3/5 signaling pathway.
Mu W, Ao J, Li Y, Zhang J, Duan C
Journal of ethnopharmacology 2022 Oct 5;296:115507
Journal of ethnopharmacology 2022 Oct 5;296:115507
Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation.
Wang Y, Karki R, Mall R, Sharma BR, Kalathur RC, Lee S, Kancharana B, So M, Combs KL, Kanneganti TD
Cell reports 2022 Oct 4;41(1):111434
Cell reports 2022 Oct 4;41(1):111434
CTRP1 prevents high fat diet-induced obesity and improves glucose homeostasis in obese and STZ-induced diabetic mice.
Ren M, Pan J, Yu X, Chang K, Yuan X, Zhang C
Journal of translational medicine 2022 Oct 4;20(1):449
Journal of translational medicine 2022 Oct 4;20(1):449
Upregulation of CRABP2 by TET1-mediated DNA hydroxymethylation attenuates mitochondrial apoptosis and promotes oxaliplatin resistance in gastric cancer.
Tang X, Liang Y, Sun G, He Q, Hou Z, Jiang X, Gao P, Qu H
Cell death & disease 2022 Oct 4;13(10):848
Cell death & disease 2022 Oct 4;13(10):848
Z. morio Hemolymph Relieves E. coli-Induced Mastitis by Inhibiting Inflammatory Response and Repairing the Blood-Milk Barrier.
Zou Y, Wang X, Xu J, Wang S, Li S, Zhu Y, Wang J
International journal of molecular sciences 2022 Oct 31;23(21)
International journal of molecular sciences 2022 Oct 31;23(21)
Injectable and reactive oxygen species-scavenging gelatin hydrogel promotes neural repair in experimental traumatic brain injury.
Zhang D, Chang R, Ren Y, He Y, Guo S, Guan F, Yao M
International journal of biological macromolecules 2022 Oct 31;219:844-863
International journal of biological macromolecules 2022 Oct 31;219:844-863
Preparation of curcumin-loaded cochleates: characterisation, stability and antioxidant properties.
Chen L, Yue B, Liu Z, Luo Y, Ni L, Shen W, Zhou Z, Ge X
Food & function 2022 Oct 31;13(21):11273-11282
Food & function 2022 Oct 31;13(21):11273-11282
Lysine acetylome profiling in mouse hippocampus and its alterations upon FMRP deficiency linked to abnormal energy metabolism.
Wu YY, Yang C, Yan HJ, Lu P, Zhang L, Feng WC, Long YS
Journal of proteomics 2022 Oct 30;269:104720
Journal of proteomics 2022 Oct 30;269:104720
Interferon-Inducible Transmembrane Protein 3 (IFITM3) Restricts Rotavirus Infection.
Pang Z, Hao P, Qu Q, Li L, Jiang Y, Xiao S, Jin N, Li C
Viruses 2022 Oct 30;14(11)
Viruses 2022 Oct 30;14(11)
VAMP4 regulates insulin levels by targeting secretory granules to lysosomes.
Li M, Feng F, Feng H, Hu P, Xue Y, Xu T, Song E
The Journal of cell biology 2022 Oct 3;221(10)
The Journal of cell biology 2022 Oct 3;221(10)
Down-regulation of NR2B receptors contributes to the analgesic and antianxiety effects of enriched environment mediated by endocannabinoid system in the inflammatory pain mice.
Jiang S, Zheng C, Wen G, Bu B, Zhao S, Xu X
Behavioural brain research 2022 Oct 28;435:114062
Behavioural brain research 2022 Oct 28;435:114062
Srolo Bzhtang reduces inflammation and vascular remodeling via suppression of the MAPK/NF-κB signaling pathway in rats with pulmonary arterial hypertension.
Chen T, Su S, Yang Z, Zhang D, Li Z, Lu D
Journal of ethnopharmacology 2022 Oct 28;297:115572
Journal of ethnopharmacology 2022 Oct 28;297:115572
RTCB Complex Regulates Stress-Induced tRNA Cleavage.
Akiyama Y, Takenaka Y, Kasahara T, Abe T, Tomioka Y, Ivanov P
International journal of molecular sciences 2022 Oct 28;23(21)
International journal of molecular sciences 2022 Oct 28;23(21)
Auxin and abscisic acid antagonistically regulate ascorbic acid production via the SlMAPK8-SlARF4-SlMYB11 module in tomato.
Xu X, Zhang Q, Gao X, Wu G, Wu M, Yuan Y, Zheng X, Gong Z, Hu X, Gong M, Qi T, Li H, Luo Z, Li Z, Deng W
The Plant cell 2022 Oct 27;34(11):4409-4427
The Plant cell 2022 Oct 27;34(11):4409-4427
Granulocytic MDSC with Deficient CCR5 Alleviates Lipogenesis and Inflammation in Nonalcoholic Fatty Liver Disease.
Liao TC, Huang JP, Tsai YT, Shih WC, Juan CC, Hsieh PS, Hung LM, Yu CL
International journal of molecular sciences 2022 Oct 27;23(21)
International journal of molecular sciences 2022 Oct 27;23(21)
Neuropilin-1 Facilitates Pseudorabies Virus Replication and Viral Glycoprotein B Promotes Its Degradation in a Furin-Dependent Manner.
Chen M, Wang MH, Shen XG, Liu H, Zhang YY, Peng JM, Meng F, Wang TY, Bai YZ, Sun MX, Tian ZJ, Yin X, Cai XH, Tang YD
Journal of virology 2022 Oct 26;96(20):e0131822
Journal of virology 2022 Oct 26;96(20):e0131822
Circ007071 Inhibits Unsaturated Fatty Acid Synthesis by Interacting with miR-103-5p to Enhance PPARγ Expression in the Dairy Goat Mammary Gland.
Chen Z, Lu Q, Zhang X, Zhang Z, Cao X, Wang K, Lu X, Yang Z, Loor JJ, Jiao P
Journal of agricultural and food chemistry 2022 Oct 26;70(42):13719-13729
Journal of agricultural and food chemistry 2022 Oct 26;70(42):13719-13729
Fucosylated Chondroitin Sulfate against Parkinson's Disease through Inhibiting Inflammation Induced by Gut Dysbiosis.
Liu Y, Liu X, Ye Q, Wang Y, Zhang J, Lin S, Wang G, Yang X, Zhang J, Chen S, Wu N
Journal of agricultural and food chemistry 2022 Oct 26;70(42):13676-13691
Journal of agricultural and food chemistry 2022 Oct 26;70(42):13676-13691
The oncoprotein MUC1 facilitates breast cancer progression by promoting Pink1-dependent mitophagy via ATAD3A destabilization.
Li Q, Chu Y, Li S, Yu L, Deng H, Liao C, Liao X, Yang C, Qi M, Cheng J, Chen G, Huang L
Cell death & disease 2022 Oct 26;13(10):899
Cell death & disease 2022 Oct 26;13(10):899
METTL3 acetylation impedes cancer metastasis via fine-tuning its nuclear and cytosolic functions.
Li Y, He X, Lu X, Gong Z, Li Q, Zhang L, Yang R, Wu C, Huang J, Ding J, He Y, Liu W, Chen C, Cao B, Zhou D, Shi Y, Chen J, Wang C, Zhang S, Zhang J, Ye J, You H
Nature communications 2022 Oct 26;13(1):6350
Nature communications 2022 Oct 26;13(1):6350
Environmentally-relevant concentrations of the antipsychotic drugs sulpiride and clozapine induce abnormal dopamine and serotonin signaling in zebrafish brain.
Zhang B, Peng X, Sun X, Guo Y, Li T
Scientific reports 2022 Oct 26;12(1):17973
Scientific reports 2022 Oct 26;12(1):17973
Docetaxel-resistant triple-negative breast cancer cell-derived exosomal lncRNA LINC00667 reduces the chemosensitivity of breast cancer cells to docetaxel via targeting miR-200b-3p/Bcl-2 axis.
Li J, Kang J, Liu W, Liu J, Pan G, Mao A, Zhang Q, Lu J, Ding J, Li H
European journal of histochemistry : EJH 2022 Oct 25;66(4)
European journal of histochemistry : EJH 2022 Oct 25;66(4)
SLC38A6, regulated by EP300-mediated modifications of H3K27ac, promotes cell proliferation, glutamine metabolism and mitochondrial respiration in hepatocellular carcinoma.
Huang L, Li L, Cheng B, Xing T
Carcinogenesis 2022 Oct 22;43(9):885-894
Carcinogenesis 2022 Oct 22;43(9):885-894
The necroptosis-inducing pseudokinase mixed lineage kinase domain-like regulates the adipogenic differentiation of pre-adipocytes.
Magusto J, Beaupère C, Afonso MB, Auclair M, Delaunay JL, Soret PA, Courtois G, Aït-Slimane T, Housset C, Jéru I, Fève B, Ratziu V, Rodrigues CMP, Gautheron J
iScience 2022 Oct 21;25(10):105166
iScience 2022 Oct 21;25(10):105166
Vascular restenosis reduction with platelet membrane coated nanoparticle directed M2 macrophage polarization.
Li F, Rong Z, Zhang R, Niu S, Di X, Ni L, Liu C
iScience 2022 Oct 21;25(10):105147
iScience 2022 Oct 21;25(10):105147
Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration.
Tian H, Chen Z, Zhu X, Ou Q, Wang Z, Wu B, Xu JY, Jin C, Gao F, Wang J, Zhang J, Zhang J, Lu L, Xu GT
iScience 2022 Oct 21;25(10):105050
iScience 2022 Oct 21;25(10):105050
Histone methyltransferase Smyd2 drives adipogenesis via regulating STAT3 phosphorylation.
Su H, Meng C, Xu J, Su Z, Xiao C, Yang D
Cell death & disease 2022 Oct 21;13(10):890
Cell death & disease 2022 Oct 21;13(10):890
Argininosuccinate lyase drives activation of mutant TERT promoter in glioblastomas.
Shi Z, Ge X, Li M, Yin J, Wang X, Zhang J, Chen D, Li X, Wang X, Ji J, You Y, Qian X
Molecular cell 2022 Oct 20;82(20):3919-3931.e7
Molecular cell 2022 Oct 20;82(20):3919-3931.e7
In Vitro and In Vivo Evaluation of Antidiabetic Properties and Mechanisms of Ficus tikoua Bur.
Wang H, Zhang K, Chen X, Han M, Lu J, Zhang Y
Nutrients 2022 Oct 20;14(20)
Nutrients 2022 Oct 20;14(20)
Proteomic analysis reveals zinc-finger CCHC-type containing protein 3 as a factor inhibiting virus infection by promoting innate signaling.
Chen X, Li Z, Wang S, Tong G, Chen K, Zhao Y
Virus research 2022 Oct 2;319:198876
Virus research 2022 Oct 2;319:198876
Astragalus polysaccharide alleviated the inhibition of CSFV C-strain replication caused by PRRSV via the TLRs/NF‑κB/TNF-α pathways.
Chen D, Kang H, Tuo T, Wang L, Xia Y, Zhang Y, Zhou L, Ge X, Han J, Guo X, Yang H
Virus research 2022 Oct 2;319:198854
Virus research 2022 Oct 2;319:198854
SOX2 Promotes Invasion in Human Bladder Cancers through MMP2 Upregulation and FOXO1 Downregulation.
Xie Q, Hua X, Huang C, Liao X, Tian Z, Xu J, Zhao Y, Jiang G, Huang H, Huang C
International journal of molecular sciences 2022 Oct 19;23(20)
International journal of molecular sciences 2022 Oct 19;23(20)
High RAS-related protein Rab-7a (RAB7A) expression is a poor prognostic factor in pancreatic adenocarcinoma.
Liu Q, Bai Y, Shi X, Guo D, Wang Y, Wang Y, Guo WZ, Zhang S
Scientific reports 2022 Oct 19;12(1):17492
Scientific reports 2022 Oct 19;12(1):17492
Artemisia sphaerocephala Krasch polysaccharide promotes adipose thermogenesis and decreases obesity by shaping the gut microbiota.
Zeng X, Ren D, Li D, Du H, Yang X
Food & function 2022 Oct 17;13(20):10651-10664
Food & function 2022 Oct 17;13(20):10651-10664
PCSK9 promotes the progression and metastasis of colon cancer cells through regulation of EMT and PI3K/AKT signaling in tumor cells and phenotypic polarization of macrophages.
Wang L, Li S, Luo H, Lu Q, Yu S
Journal of experimental & clinical cancer research : CR 2022 Oct 14;41(1):303
Journal of experimental & clinical cancer research : CR 2022 Oct 14;41(1):303
Inhibition of LSD1 with Bomedemstat Sensitizes Small Cell Lung Cancer to Immune Checkpoint Blockade and T-Cell Killing.
Hiatt JB, Sandborg H, Garrison SM, Arnold HU, Liao SY, Norton JP, Friesen TJ, Wu F, Sutherland KD, Rienhoff HY, Martins R, Houghton AM, Srivastava S, MacPherson D
Clinical cancer research : an official journal of the American Association for Cancer Research 2022 Oct 14;28(20):4551-4564
Clinical cancer research : an official journal of the American Association for Cancer Research 2022 Oct 14;28(20):4551-4564
Structural analysis of the overoxidized Cu/Zn-superoxide dismutase in ROS-induced ALS filament formation.
Baek Y, Woo TG, Ahn J, Lee D, Kwon Y, Park BJ, Ha NC
Communications biology 2022 Oct 12;5(1):1085
Communications biology 2022 Oct 12;5(1):1085
LncGSAR Controls Ovarian Granulosa Cell Steroidogenesis via Sponging MiR-125b to Activate SCAP/SREBP Pathway.
Wang Y, Guo Y, Duan C, Li J, Ji S, Yan H, Liu Y, Zhang Y
International journal of molecular sciences 2022 Oct 12;23(20)
International journal of molecular sciences 2022 Oct 12;23(20)
The Effect of Circumscribed Exposure to the Pan-Aurora Kinase Inhibitor VX-680 on Proliferating Euploid Cells.
Liu X, Shi Q, Choudhry N, Zhang T, Liu H, Zhang S, Zhang J, Yang D
International journal of molecular sciences 2022 Oct 11;23(20)
International journal of molecular sciences 2022 Oct 11;23(20)
Cortisol Stimulates Local Progesterone Withdrawal Through Induction of AKR1C1 in Human Amnion Fibroblasts at Parturition.
Lu JW, Lei WJ, Ling LJ, Wang LY, Lin YK, Zhang F, Li MD, Pan F, Wang WS, Sun K
Endocrinology 2022 Oct 11;163(11)
Endocrinology 2022 Oct 11;163(11)
Characterizing and Targeting Genes Regulated by Transcription Factor MYBL2 in Lung Adenocarcinoma Cells.
Lee Y, Wu Z, Yang S, Schreiner SM, Gonzalez-Smith LD, Rhie SK
Cancers 2022 Oct 11;14(20)
Cancers 2022 Oct 11;14(20)
mTORC1 signaling pathway integrates estrogen and growth factor to coordinate vaginal epithelial cells proliferation and differentiation.
Wan S, Sun Y, Fu J, Song H, Xiao Z, Yang Q, Wang S, Yu G, Feng P, Lv W, Luo L, Guan Z, Liu F, Zhou Q, Yin Z, Yang M
Cell death & disease 2022 Oct 11;13(10):862
Cell death & disease 2022 Oct 11;13(10):862
CGG repeat expansion in NOTCH2NLC causes mitochondrial dysfunction and progressive neurodegeneration in Drosophila model.
Yu J, Liufu T, Zheng Y, Xu J, Meng L, Zhang W, Yuan Y, Hong D, Charlet-Berguerand N, Wang Z, Deng J
Proceedings of the National Academy of Sciences of the United States of America 2022 Oct 11;119(41):e2208649119
Proceedings of the National Academy of Sciences of the United States of America 2022 Oct 11;119(41):e2208649119
Stain-Free total-protein normalization enhances the reproducibility of Western blot data.
Maloy A, Alexander S, Andreas A, Nyunoya T, Chandra D
Analytical biochemistry 2022 Oct 1;654:114840
Analytical biochemistry 2022 Oct 1;654:114840
Siah1 promotes the proliferation of NSCLC cells through ubiquitinating and stabilizing Notch1.
Liu Y, Li Q, Geng L, Zhou X, Zhou X, Dong Y, Zhang Y
Experimental cell research 2022 Oct 1;419(1):113305
Experimental cell research 2022 Oct 1;419(1):113305
Exosomal circRNA Scm-like with four malignant brain tumor domains 2 (circ-SFMBT2) enhances the docetaxel resistance of prostate cancer via the microRNA-136-5p/tribbles homolog 1 pathway.
Tan X, Song X, Fan B, Li M, Zhang A, Pei L
Anti-cancer drugs 2022 Oct 1;33(9):871-882
Anti-cancer drugs 2022 Oct 1;33(9):871-882
Effect of muscone on anti-apoptotic ability of muskrat prostate primary cells.
Zhang Y, Zhao X, Man X, Ma Y, Zhang W, Wang Y, Lei X, Bai S
American journal of physiology. Regulatory, integrative and comparative physiology 2022 Oct 1;323(4):R571-R580
American journal of physiology. Regulatory, integrative and comparative physiology 2022 Oct 1;323(4):R571-R580
lncRNA UCA1 induces autophagic gene expression via epigenetic regulation mediated by ATG16L1 and miR-132-3p in SH-SY5Y cells treated with retinoic acid.
Wen F, Zhan Q, Zou T, Tan ZG, Xiang J
Epileptic disorders : international epilepsy journal with videotape 2022 Oct 1;24(5):917-927
Epileptic disorders : international epilepsy journal with videotape 2022 Oct 1;24(5):917-927
β-Arrestin2-biased Drd2 agonist UNC9995 alleviates astrocyte inflammatory injury via interaction between β-arrestin2 and STAT3 in mouse model of depression.
Liu Y, Song N, Yao H, Jiang S, Wang Y, Zheng Y, Zhou Y, Ding J, Hu G, Lu M
Journal of neuroinflammation 2022 Oct 1;19(1):240
Journal of neuroinflammation 2022 Oct 1;19(1):240
Advanced glycation end products induce Aβ(1-42) deposition and cognitive decline through H19/miR-15b/BACE1 axis in diabetic encephalopathy.
Jiang L, Yuan N, Zhao N, Tian P, Zhang D, Qin Y, Shi Z, Gao Z, Zhang N, Zhou H, Zhang R, Xu S
Brain research bulletin 2022 Oct 1;188:187-196
Brain research bulletin 2022 Oct 1;188:187-196
Inactivation of fatty acid amide hydrolase protects against ischemic reperfusion injury-induced renal fibrogenesis.
Chen C, Wang W, Poklis JL, Lichtman AH, Ritter JK, Hu G, Xie D, Li N
Biochimica et biophysica acta. Molecular basis of disease 2022 Oct 1;1868(10):166456
Biochimica et biophysica acta. Molecular basis of disease 2022 Oct 1;1868(10):166456
Role of estrogen receptors in thyroid toxicity induced by mono (2-ethylhexyl) phthalate via endoplasmic reticulum stress: An in vitro mechanistic investigation.
Xu Q, Zhou L, Ri H, Li X, Zhang X, Qi W, Ye L
Environmental toxicology and pharmacology 2022 Nov;96:104007
Environmental toxicology and pharmacology 2022 Nov;96:104007
SARS-CoV-2 ORF10 antagonizes STING-dependent interferon activation and autophagy.
Han L, Zheng Y, Deng J, Nan ML, Xiao Y, Zhuang MW, Zhang J, Wang W, Gao C, Wang PH
Journal of medical virology 2022 Nov;94(11):5174-5188
Journal of medical virology 2022 Nov;94(11):5174-5188
Plasma exosomal miR-122 regulates the efficacy of metformin via AMPK in type 2 diabetes and hepatocellular carcinoma.
Peng H, Hou M, Wu Z, Wang J, Zhou M, Zhuang X, Xing J, Tao Q, Huang L, Zhou F, Zhang S, Feng Q, Hou Y, Yu Q
Heliyon 2022 Nov;8(11):e11503
Heliyon 2022 Nov;8(11):e11503
Carboxylesterase 2 induces mitochondrial dysfunction via disrupting lipid homeostasis in oral squamous cell carcinoma.
Chen X, Liu Q, Chen Y, Wang L, Yang R, Zhang W, Pan X, Zhang S, Chen C, Wu T, Xia J, Cheng B, Chen X, Ren X
Molecular metabolism 2022 Nov;65:101600
Molecular metabolism 2022 Nov;65:101600
CCT4 knockdown enhances the sensitivity of cisplatin by inhibiting glycolysis in human esophageal squamous cell carcinomas.
Fang J, Ma Y, Li Y, Li J, Zhang X, Han X, Ma S, Guan F
Molecular carcinogenesis 2022 Nov;61(11):1043-1055
Molecular carcinogenesis 2022 Nov;61(11):1043-1055
Mutations in GCK May Lead to MODY2 by Reducing Glycogen Synthesis.
Li Z, Li K, Sun Y, Jiang X, Liu J, Li J, Fang L, Li G, Guan Q, Xu C
Advanced biology 2022 Nov;6(11):e2200097
Advanced biology 2022 Nov;6(11):e2200097
Ergosterol increases 7-dehydrocholesterol, a cholesterol precursor, and decreases cholesterol in human HepG2 cells.
Kuwabara N, Ohta-Shimizu M, Fuwa F, Tomitsuka E, Sato S, Nakagawa S
Lipids 2022 Nov;57(6):303-311
Lipids 2022 Nov;57(6):303-311
NINJ1 triggers extravillous trophoblast cell dysfunction through blocking the STAT3 signaling pathway.
Zhang X, Chen Y, Wang X, Zhang Z, Wang J, Shen Y, Hu Y, Wu X
Genes & genomics 2022 Nov;44(11):1385-1397
Genes & genomics 2022 Nov;44(11):1385-1397
AIMP1 promotes multiple myeloma malignancy through interacting with ANP32A to mediate histone H3 acetylation.
Wei R, Zhu Y, Zhang Y, Zhao W, Yu X, Wang L, Gu C, Gu X, Yang Y
Cancer communications (London, England) 2022 Nov;42(11):1185-1206
Cancer communications (London, England) 2022 Nov;42(11):1185-1206
Targeting epiregulin in the treatment-damaged tumor microenvironment restrains therapeutic resistance.
Wang C, Long Q, Fu Q, Xu Q, Fu D, Li Y, Gao L, Guo J, Zhang X, Lam EW, Campisi J, Sun Y
Oncogene 2022 Nov;41(45):4941-4959
Oncogene 2022 Nov;41(45):4941-4959
Repurposing an Antiepileptic Drug for the Treatment of Glioblastoma.
Yadav A, Alnakhli A, Vemana HP, Bhutkar S, Muth A, Dukhande VV
Pharmaceutical research 2022 Nov;39(11):2871-2883
Pharmaceutical research 2022 Nov;39(11):2871-2883
Cancer-associated fibroblast-secreted miR-421 promotes pancreatic cancer by regulating the SIRT3/H3K9Ac/HIF-1α axis.
Zhou B, Lei JH, Wang Q, Qu TF, Cha LC, Zhan HX, Liu SL, Hu X, Sun CD, Guo WD, Qiu FB, Cao JY
The Kaohsiung journal of medical sciences 2022 Nov;38(11):1080-1092
The Kaohsiung journal of medical sciences 2022 Nov;38(11):1080-1092
Disturbing NLRP3 acetylation and inflammasome assembly inhibits androgen receptor-promoted inflammatory responses and prostate cancer progression.
Zhao AN, Yang Z, Wang DD, Shi B, Zhang H, Bai Y, Yan BW, Zhang Y, Wen JK, Wang XL, Qu CB
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Nov;36(11):e22602
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Nov;36(11):e22602
Total flavonoids from the dried root of Tetrastigma hemsleyanum Diels et Gilg inhibit colorectal cancer growth through PI3K/AKT/mTOR signaling pathway.
Zhai Y, Sun J, Sun C, Zhao H, Li X, Yao J, Su J, Xu X, Xu X, Hu J, Daglia M, Han B, Kai G
Phytotherapy research : PTR 2022 Nov;36(11):4263-4277
Phytotherapy research : PTR 2022 Nov;36(11):4263-4277
Wogonoside attenuates liver fibrosis by triggering hepatic stellate cell ferroptosis through SOCS1/P53/SLC7A11 pathway.
Liu G, Wei C, Yuan S, Zhang Z, Li J, Zhang L, Wang G, Fang L
Phytotherapy research : PTR 2022 Nov;36(11):4230-4243
Phytotherapy research : PTR 2022 Nov;36(11):4230-4243
The role of reelin in the pathological mechanism of depression from clinical to rodents.
Jin K, Zhang S, Jiang C, Liu R, Chen B, Zhao H, Zhang Q, Shen Z, Xu P, Hu X, Jiao J, Lu J, Huang M
Psychiatry research 2022 Nov;317:114838
Psychiatry research 2022 Nov;317:114838
Specific targeting of glioblastoma with an oncolytic virus expressing a cetuximab-CCL5 fusion protein via innate and adaptive immunity.
Tian L, Xu B, Chen Y, Li Z, Wang J, Zhang J, Ma R, Cao S, Hu W, Chiocca EA, Kaur B, Caligiuri MA, Yu J
Nature cancer 2022 Nov;3(11):1318-1335
Nature cancer 2022 Nov;3(11):1318-1335
Atg6 promotes organismal health by suppression of cell stress and inflammation.
Shen JL, Doherty J, Allen E, Fortier TM, Baehrecke EH
Cell death and differentiation 2022 Nov;29(11):2275-2287
Cell death and differentiation 2022 Nov;29(11):2275-2287
Wnt/beta-catenin signaling confers ferroptosis resistance by targeting GPX4 in gastric cancer.
Wang Y, Zheng L, Shang W, Yang Z, Li T, Liu F, Shao W, Lv L, Chai L, Qu L, Xu Q, Du J, Liang X, Zeng J, Jia J
Cell death and differentiation 2022 Nov;29(11):2190-2202
Cell death and differentiation 2022 Nov;29(11):2190-2202
PTX3 mediates the infiltration, migration, and inflammation-resolving-polarization of macrophages in glioblastoma.
Zhang H, Wang Y, Zhao Y, Liu T, Wang Z, Zhang N, Dai Z, Wu W, Cao H, Feng S, Zhang L, Cheng Q, Liu Z
CNS neuroscience & therapeutics 2022 Nov;28(11):1748-1766
CNS neuroscience & therapeutics 2022 Nov;28(11):1748-1766
KLF16 inhibits PEDV replication by activating the type I IFN signaling pathway.
Dong S, Kong N, Shen H, Li Y, Qin W, Zhai H, Zhai X, Yang X, Ye C, Ye M, Liu C, Yu L, Zheng H, Tong W, Yu H, Zhang W, Tong G, Shan T
Veterinary microbiology 2022 Nov;274:109577
Veterinary microbiology 2022 Nov;274:109577
LOC102553417 silencing facilitates the apoptosis of hepatic stellate cells via the miR‑30e/MTDH axis.
Wei W, Lin C, Hu R, Huang J, Chen X, Zhou L, Wei J, Deng YB, Wang CF
Molecular medicine reports 2022 Nov;26(5)
Molecular medicine reports 2022 Nov;26(5)
IL-17A promotes lung fibrosis through impairing mitochondrial homeostasis in type II alveolar epithelial cells.
Xiao H, Peng L, Jiang D, Liu Y, Zhu L, Li Z, Geng J, Xie B, Huang X, Wang J, Dai H, Wang C
Journal of cellular and molecular medicine 2022 Nov;26(22):5728-5741
Journal of cellular and molecular medicine 2022 Nov;26(22):5728-5741
High expression of HOXA4 in patients with glioma indicates unfavorable clinical outcomes.
Yu Z, Liu Z, Lian X, Cheng X, Liu B, Zhang B, Wang H, Wang J, Li A, Ren Z, Pang B, Qian R, Gao Y
Cell cycle (Georgetown, Tex.) 2022 Nov;21(22):2387-2402
Cell cycle (Georgetown, Tex.) 2022 Nov;21(22):2387-2402
A single N6-methyladenosine site regulates lncRNA HOTAIR function in breast cancer cells.
Porman AM, Roberts JT, Duncan ED, Chrupcala ML, Levine AA, Kennedy MA, Williams MM, Richer JK, Johnson AM
PLoS biology 2022 Nov;20(11):e3001885
PLoS biology 2022 Nov;20(11):e3001885
Intermittent fasting protects against Alzheimer's disease in mice by altering metabolism through remodeling of the gut microbiota.
Pan RY, Zhang J, Wang J, Wang Y, Li Z, Liao Y, Liao Y, Zhang C, Liu Z, Song L, Yu J, Yuan Z
Nature aging 2022 Nov;2(11):1024-1039
Nature aging 2022 Nov;2(11):1024-1039
Small immune effectors coordinate peptidoglycan-derived immunity to regulate intestinal bacteria in shrimp.
Liu PP, Wei Z, Cheng ZH, Wang XW
PLoS pathogens 2022 Nov;18(11):e1010967
PLoS pathogens 2022 Nov;18(11):e1010967
Si-Wu-Tang ameliorates bile duct ligation-induced liver fibrosis via modulating immune environment.
Ma Z, Xue X, Bai J, Cai Y, Jin X, Jia K, Ding M, Lyu X, Li X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113834
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113834
The dipeptidyl peptidase-4 inhibitor linagliptin ameliorates LPS-induced acute lung injury by maintenance of pulmonary microvascular barrier via activating the Epac1/AKT pathway.
Zhang N, Tang S, Zhang J, Pei B, Pang T, Sun G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113704
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113704
B-cell receptor associated protein 31 deficiency decreases the expression of adhesion molecule CD11b/CD18 and PSGL-1 in neutrophils to ameliorate acute lung injury.
Li GX, Jiang XH, Zang JN, Zhu BZ, Jia CC, Niu KW, Liu X, Jiang R, Wang B
The international journal of biochemistry & cell biology 2022 Nov;152:106299
The international journal of biochemistry & cell biology 2022 Nov;152:106299
LncRNA TM1-3P Regulates Proliferation, Apoptosis and Inflammation of Fibroblasts in Osteoarthritis through miR-144-3p/ONECUT2 Axis.
Yi Y, Yang N, Yang Z, Tao X, Li Y
Orthopaedic surgery 2022 Nov;14(11):3078-3091
Orthopaedic surgery 2022 Nov;14(11):3078-3091
A novel ceRNA regulatory network involving the long noncoding NEAT1, miRNA-466f-3p and its mRNA target in osteoblast autophagy and osteoporosis.
Zhao X, Zhao D, Geng B, Yaobin W, Xia Y
Journal of molecular medicine (Berlin, Germany) 2022 Nov;100(11):1629-1646
Journal of molecular medicine (Berlin, Germany) 2022 Nov;100(11):1629-1646
Schisandra chinensis Lignans Exert Antidepressant Effects by Promoting BV2 Microglia Polarization toward the M2 Phenotype through the Activation of the Cannabinoid Receptor Type-2-Signal Transducer and Activator of Transcription 6 Pathway.
Wang J, Zhang G, Yang Y, Zhang X, Shi K, Zhang X, Yan T, Jia Y
Journal of agricultural and food chemistry 2022 Nov 9;70(44):14157-14169
Journal of agricultural and food chemistry 2022 Nov 9;70(44):14157-14169
In Vivo Visualization of RNAi Efficiency Using a Pumilio/FBF Protein-Based Reporter.
Shi X, Hu C, Jiang Y, Lei Z, Zhang C, Zhang B, Wang F
Analytical chemistry 2022 Nov 8;94(44):15525-15533
Analytical chemistry 2022 Nov 8;94(44):15525-15533
Increased joint loading induces subchondral bone loss of the temporomandibular joint via the RANTES-CCRs-Akt2 axis.
Feng SY, Lei J, Li YX, Shi WG, Wang RR, Yap AU, Wang YX, Fu KY
JCI insight 2022 Nov 8;7(21)
JCI insight 2022 Nov 8;7(21)
Glucosamine delays the progression of osteoporosis in senile mice by promoting osteoblast autophagy.
Su W, Lv C, Huang L, Zheng X, Yang S
Nutrition & metabolism 2022 Nov 8;19(1):75
Nutrition & metabolism 2022 Nov 8;19(1):75
E3 Ubiquitin Ligase FBXO3 Drives Neuroinflammation to Aggravate Cerebral Ischemia/Reperfusion Injury.
Gao Y, Xiao X, Luo J, Wang J, Peng Q, Zhao J, Jiang N, Zhao Y
International journal of molecular sciences 2022 Nov 7;23(21)
International journal of molecular sciences 2022 Nov 7;23(21)
UNC13D inhibits STING signaling by attenuating its oligomerization on the endoplasmic reticulum.
Song P, Yang W, Lou KF, Dong H, Zhang H, Wang B, Chen D
EMBO reports 2022 Nov 7;23(11):e55099
EMBO reports 2022 Nov 7;23(11):e55099
TRIM50 promotes NLRP3 inflammasome activation by directly inducing NLRP3 oligomerization.
Lin Y, Lv X, Sun C, Sun Y, Yang M, Ma D, Jing W, Zhao Y, Cheng Y, Xuan H, Han L
EMBO reports 2022 Nov 7;23(11):e54569
EMBO reports 2022 Nov 7;23(11):e54569
The tyrosine phosphorylation of GRK2 is responsible for activated D(2)R-mediated insulin resistance.
Gao Z, Min X, Kim KM, Liu H, Hu L, Wu C, Zhang X
Biochemical and biophysical research communications 2022 Nov 5;628:40-48
Biochemical and biophysical research communications 2022 Nov 5;628:40-48
Cadmium-induced apoptosis of Leydig cells is mediated by excessive mitochondrial fission and inhibition of mitophagy.
Yi L, Shang XJ, Lv L, Wang Y, Zhang J, Quan C, Shi Y, Liu Y, Zhang L
Cell death & disease 2022 Nov 5;13(11):928
Cell death & disease 2022 Nov 5;13(11):928
Defective Human SRP Induces Protein Quality Control and Triggers Stress Response.
Tikhonova EB, Gutierrez Guarnizo SA, Kellogg MK, Karamyshev A, Dozmorov IM, Karamysheva ZN, Karamyshev AL
Journal of molecular biology 2022 Nov 30;434(22):167832
Journal of molecular biology 2022 Nov 30;434(22):167832
Metformin alleviates HFD-induced oxidative stress in hepatocyte via activating SIRT6/PGC-1α/ENDOG signaling.
Gao S, Yang Q, Liu Z, Kong W, Chen J, Li X, Peng Y, Bao M, Bian X, Zhang Y, Jiang Q, Li Z, Zhang Y, Yan F, Ye J
Clinical science (London, England : 1979) 2022 Nov 30;136(22):1711-1730
Clinical science (London, England : 1979) 2022 Nov 30;136(22):1711-1730
Transcriptome Analysis of Protection by Dendrobium Nobile Alkaloids (DNLA) against Chronic Alcoholic Liver Injury in Mice.
Huang X, Yang S, Sun J, Li X, Zhou SY, Shi JS, Liu J, Wu Q
Biomedicines 2022 Nov 3;10(11)
Biomedicines 2022 Nov 3;10(11)
Tim-4 reprograms cholesterol metabolism to suppress antiviral innate immunity by disturbing the Insig1-SCAP interaction in macrophages.
Wang Y, Wang Y, Ding L, Ren X, Wang B, Wang L, Zhao S, Yue X, Wu Z, Li C, Liang X, Ma C, Gao L
Cell reports 2022 Nov 29;41(9):111738
Cell reports 2022 Nov 29;41(9):111738
IPO7 Promotes Odontoblastic Differentiation and Inhibits Osteoblastic Differentiation Through Regulation of RUNX2 Expression and Translocation.
Zhang Y, Zhang H, Xiao Z, Yuan G, Yang G
Stem cells (Dayton, Ohio) 2022 Nov 29;40(11):1020-1030
Stem cells (Dayton, Ohio) 2022 Nov 29;40(11):1020-1030
De novo pyrimidine synthesis fuels glycolysis and confers chemoresistance in gastric cancer.
He D, Chen M, Chang L, Gu J, Liu F, Gao X, Ruan Y
Cancer letters 2022 Nov 28;549:215837
Cancer letters 2022 Nov 28;549:215837
Pathological characterization of a novel mouse model expressing the PD-linked CHCHD2-T61I mutation.
Kee TR, Wehinger JL, Gonzalez PE, Nguyen E, McGill Percy KC, Khan SA, Chaput D, Wang X, Liu T, Kang DE, Woo JA
Human molecular genetics 2022 Nov 28;31(23):3987-4005
Human molecular genetics 2022 Nov 28;31(23):3987-4005
Ciclopirox drives growth arrest and autophagic cell death through STAT3 in gastric cancer cells.
Chen L, Chen D, Li J, He L, Chen T, Song D, Shan S, Wang J, Lu X, Lu B
Cell death & disease 2022 Nov 28;13(11):1007
Cell death & disease 2022 Nov 28;13(11):1007
Targeting APLN/APJ restores blood-testis barrier and improves spermatogenesis in murine and human diabetic models.
Song K, Yang X, An G, Xia X, Zhao J, Xu X, Wan C, Liu T, Zheng Y, Ren S, Wang M, Chang G, Cronin SJF, Penninger JM, Jing T, Ou X, Rao S, Liu Z, Zhao XY
Nature communications 2022 Nov 28;13(1):7335
Nature communications 2022 Nov 28;13(1):7335
Secreted EMC10 is upregulated in human obesity and its neutralizing antibody prevents diet-induced obesity in mice.
Wang X, Li Y, Qiang G, Wang K, Dai J, McCann M, Munoz MD, Gil V, Yu Y, Li S, Yang Z, Xu S, Cordoba-Chacon J, De Jesus DF, Sun B, Chen K, Wang Y, Liu X, Miao Q, Zhou L, Hu R, Ding Q, Kulkarni RN, Gao D, Blüher M, Liew CW
Nature communications 2022 Nov 28;13(1):7323
Nature communications 2022 Nov 28;13(1):7323
Monochromatic Light Pollution Exacerbates High-Fat Diet-Induced Adipocytic Hypertrophy in Mice.
Guan Q, Li Y, Wang Z, Cao J, Dong Y, Ren F, Chen Y
Cells 2022 Nov 28;11(23)
Cells 2022 Nov 28;11(23)
Resident intruder paradigm-induced PMDD rat model of premenstrual irritability: behavioral phenotypes, drug intervention, and biomarkers.
Gao M, Zhang H, Gao Z, Sun Y, Xu G, Wei F, Wang J, Gao D
Aging 2022 Nov 27;14(22):9210-9220
Aging 2022 Nov 27;14(22):9210-9220
The Clostridium Metabolite P-Cresol Sulfate Relieves Inflammation of Primary Biliary Cholangitis by Regulating Kupffer Cells.
Fu HY, Xu JM, Ai X, Dang FT, Tan X, Yu HY, Feng J, Yang WX, Ma HT, Tu RF, Gupta AK, Manandhar LK, Bao WM, Tang YM
Cells 2022 Nov 26;11(23)
Cells 2022 Nov 26;11(23)
USP14 regulates cell cycle progression through deubiquitinating CDK1 in breast cancer.
Liu Y, Xu J, Wang Y, Gan M, Hu Q, Wang J, Han T
Acta biochimica et biophysica Sinica 2022 Nov 25;54(11):1610-1618
Acta biochimica et biophysica Sinica 2022 Nov 25;54(11):1610-1618
Exploring the Effective Components and Mechanism of Action of Japanese Ardisia in the Treatment of Autoimmune Hepatitis Based on Network Pharmacology and Experimental Verification.
Fu T, Chen Y, Li J, Zhu P, He H, Zhang W, Yung KKL, Wu W
Pharmaceuticals (Basel, Switzerland) 2022 Nov 24;15(12)
Pharmaceuticals (Basel, Switzerland) 2022 Nov 24;15(12)
Orally Administered Ginkgolide C Attenuates DSS-Induced Colitis by Maintaining Gut Barrier Integrity, Inhibiting Inflammatory Responses, and Regulating Intestinal Flora.
Xu D, Zhuang L, Gao S, Ma H, Cheng J, Liu J, Liu D, Fu S, Hu G
Journal of agricultural and food chemistry 2022 Nov 23;70(46):14718-14731
Journal of agricultural and food chemistry 2022 Nov 23;70(46):14718-14731
Branched-chain amino acid catabolism breaks glutamine addiction to sustain hepatocellular carcinoma progression.
Yang D, Liu H, Cai Y, Lu K, Zhong X, Xing S, Song W, Zhang Y, Ye L, Zhu X, Wang T, Zhang P, Li ST, Feng J, Jia W, Zhang H, Gao P
Cell reports 2022 Nov 22;41(8):111691
Cell reports 2022 Nov 22;41(8):111691
Adenosine deaminase acting on RNA-1 is essential for early B lymphopoiesis.
Chen W, Li Y, Ruan GX, Huang H, Zhang R, Wang J, Ouyang Y, Li Y, Xu S, Ou X
Cell reports 2022 Nov 22;41(8):111687
Cell reports 2022 Nov 22;41(8):111687
Effective-component compatibility of Bufei Yishen formula III ameliorated COPD by improving airway epithelial cell senescence by promoting mitophagy via the NRF2/PINK1 pathway.
Li MY, Qin YQ, Tian YG, Li KC, Oliver BG, Liu XF, Zhao P, Li JS
BMC pulmonary medicine 2022 Nov 22;22(1):434
BMC pulmonary medicine 2022 Nov 22;22(1):434
Functionally integrating nanoparticles alleviate deep vein thrombosis in pregnancy and rescue intrauterine growth restriction.
Cheng J, Zhang S, Li C, Li K, Jia X, Wei Q, Qi H, Zhang J
Nature communications 2022 Nov 22;13(1):7166
Nature communications 2022 Nov 22;13(1):7166
IL-37 alleviates Coxsackievirus B3-induced viral myocarditis via inhibiting NLRP3 inflammasome-mediated pyroptosis.
Sun L, Yuan H, Zhao G
Scientific reports 2022 Nov 22;12(1):20077
Scientific reports 2022 Nov 22;12(1):20077
Dihydromyricetin Attenuates Depressive-like Behaviors in Mice by Inhibiting the AGE-RAGE Signaling Pathway.
Huang J, Chen B, Wang H, Hu S, Yu X, Reilly J, He Z, You Y, Shu X
Cells 2022 Nov 22;11(23)
Cells 2022 Nov 22;11(23)
Essential role of MESP1-RING1A complex in cardiac differentiation.
Liang Q, Wang S, Zhou X, Li Y, Xing S, Sha Y, Yang F, Huang W, Liu N, Li Z, Chen Y, Xu Y, Zhu P, Lan F, Sun N
Developmental cell 2022 Nov 21;57(22):2533-2549.e7
Developmental cell 2022 Nov 21;57(22):2533-2549.e7
Characterization of Mitochondrial Alterations in Aicardi-Goutières Patients Mutated in RNASEH2A and RNASEH2B Genes.
Dragoni F, Garau J, Sproviero D, Orcesi S, Varesio C, De Siervi S, Gagliardi S, Cereda C, Pansarasa O
International journal of molecular sciences 2022 Nov 21;23(22)
International journal of molecular sciences 2022 Nov 21;23(22)
Apigenin Ameliorates Hyperuricemia and Renal Injury through Regulation of Uric Acid Metabolism and JAK2/STAT3 Signaling Pathway.
Liu T, Gao H, Zhang Y, Wang S, Lu M, Dai X, Liu Y, Shi H, Xu T, Yin J, Gao S, Wang L, Zhang D
Pharmaceuticals (Basel, Switzerland) 2022 Nov 21;15(11)
Pharmaceuticals (Basel, Switzerland) 2022 Nov 21;15(11)
BP5 alleviates endotoxemia-induced acute lung injury by activating Nrf2 via dual regulation of the Keap1-Nrf2 interaction and the Akt (Ser473)/GSK3β (Ser9)/Fyn pathway.
Li T, Geng Z, Zhang J, Xu L, Zhu X
Free radical biology & medicine 2022 Nov 20;193(Pt 1):304-318
Free radical biology & medicine 2022 Nov 20;193(Pt 1):304-318
CRISPR-mediated MECOM depletion retards tumor growth by reducing cancer stem cell properties in lung squamous cell carcinoma.
Ma Y, Kang B, Li S, Xie G, Bi J, Li F, An G, Liu B, Li J, Shen Y, Xu X, Yang H, Yang Y, Gu Y, Wu N
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Nov 2;30(11):3341-3357
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Nov 2;30(11):3341-3357
Cyanidin Chloride Improves LPS-Induced Depression-Like Behavior in Mice by Ameliorating Hippocampal Inflammation and Excitotoxicity.
Qu D, Ye Z, Zhang W, Dai B, Chen G, Wang L, Shao X, Xiang A, Lu Z, Shi J
ACS chemical neuroscience 2022 Nov 2;13(21):3023-3033
ACS chemical neuroscience 2022 Nov 2;13(21):3023-3033
Girdin Promotes Tumorigenesis and Chemoresistance in Lung Adenocarcinoma by Interacting with PKM2.
Cao F, Yang D, Tang F, Lu C, He X, Chen S, Yang Z, Gong S, Sun L, Enomoto A, Takahashi M, Weng L
Cancers 2022 Nov 19;14(22)
Cancers 2022 Nov 19;14(22)
HBO1 catalyzes lysine benzoylation in mammalian cells.
Tan D, Wei W, Han Z, Ren X, Yan C, Qi S, Song X, Zheng YG, Wong J, Huang H
iScience 2022 Nov 18;25(11):105443
iScience 2022 Nov 18;25(11):105443
In vitro evaluation of platelet extracellular vesicles (PEVs) for corneal endothelial regeneration.
Widyaningrum R, Wu YW, Delila L, Lee DY, Wang TJ, Burnouf T
Platelets 2022 Nov 17;33(8):1237-1250
Platelets 2022 Nov 17;33(8):1237-1250
Circular RNA circPTPRF promotes the progression of GBM via sponging miR-1208 to up-regulate YY1.
Zhou J, Wang C, Liu Y, Cui D, Wang Z, Jiang Y, Gao L
Cancer cell international 2022 Nov 17;22(1):359
Cancer cell international 2022 Nov 17;22(1):359
Identification of purine biosynthesis as an NADH-sensing pathway to mediate energy stress.
Yang R, Yang C, Ma L, Zhao Y, Guo Z, Niu J, Chu Q, Ma Y, Li B
Nature communications 2022 Nov 17;13(1):7031
Nature communications 2022 Nov 17;13(1):7031
Palmitic Acid Promotes Lung Metastasis of Melanomas via the TLR4/TRIF-Peli1-pNF-κB Pathway.
Zhang X, Li X, Xiong G, Yun F, Feng Y, Ni Q, Wu N, Yang L, Yi Z, Zhang Q, Yang Z, Kuang Y, Sai B, Zhu Y
Metabolites 2022 Nov 17;12(11)
Metabolites 2022 Nov 17;12(11)
Bone marrow-targetable Green Tea Catechin-Based Micellar Nanocomplex for synergistic therapy of Acute myeloid leukemia.
Bae KH, Lai F, Mong J, Niibori-Nambu A, Chan KH, Her Z, Osato M, Tan MH, Chen Q, Kurisawa M
Journal of nanobiotechnology 2022 Nov 16;20(1):481
Journal of nanobiotechnology 2022 Nov 16;20(1):481
LncRNA Airn alleviates diabetic cardiac fibrosis by inhibiting activation of cardiac fibroblasts via a m6A-IMP2-p53 axis.
Peng T, Liu M, Hu L, Guo D, Wang D, Qi B, Ren G, Hu C, Zhang F, Chun HJ, Song L, Hu J, Li Y
Biology direct 2022 Nov 16;17(1):32
Biology direct 2022 Nov 16;17(1):32
Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR cytosolic complex.
Gruszczyk J, Grandvuillemin L, Lai-Kee-Him J, Paloni M, Savva CG, Germain P, Grimaldi M, Boulahtouf A, Kwong HS, Bous J, Ancelin A, Bechara C, Barducci A, Balaguer P, Bourguet W
Nature communications 2022 Nov 16;13(1):7010
Nature communications 2022 Nov 16;13(1):7010
Tea Tree Oil Mediates Antioxidant Factors Relish and Nrf2-Autophagy Axis Regulating the Lipid Metabolism of Macrobrachium rosenbergii.
Liu M, Zheng X, Sun C, Zhou Q, Liu B, Xu P
Antioxidants (Basel, Switzerland) 2022 Nov 16;11(11)
Antioxidants (Basel, Switzerland) 2022 Nov 16;11(11)
Cadmium exposure induces pyroptosis in testicular tissue by increasing oxidative stress and activating the AIM2 inflammasome pathway.
Zhou J, Zeng L, Zhang Y, Wang M, Li Y, Jia Y, Wu L, Su P
The Science of the total environment 2022 Nov 15;847:157500
The Science of the total environment 2022 Nov 15;847:157500
Schisandra chinensis (Turcz.) Baill. Protects against DSS-induced colitis in mice: Involvement of TLR4/NF-κB/NLRP3 inflammasome pathway and gut microbiota.
Bian Z, Qin Y, Li L, Su L, Fei C, Li Y, Hu M, Chen X, Zhang W, Mao C, Yuan X, Lu T, Ji D
Journal of ethnopharmacology 2022 Nov 15;298:115570
Journal of ethnopharmacology 2022 Nov 15;298:115570
Anti-infective therapy using species-specific activators of Staphylococcus aureus ClpP.
Wei B, Zhang T, Wang P, Pan Y, Li J, Chen W, Zhang M, Ji Q, Wu W, Lan L, Gan J, Yang CG
Nature communications 2022 Nov 14;13(1):6909
Nature communications 2022 Nov 14;13(1):6909
Promoting Effect of L-Fucose on the Regeneration of Intestinal Stem Cells through AHR/IL-22 Pathway of Intestinal Lamina Propria Monocytes.
Tan C, Hong G, Wang Z, Duan C, Hou L, Wu J, Qian W, Han C, Hou X
Nutrients 2022 Nov 12;14(22)
Nutrients 2022 Nov 12;14(22)
Generative deep learning enables the discovery of a potent and selective RIPK1 inhibitor.
Li Y, Zhang L, Wang Y, Zou J, Yang R, Luo X, Wu C, Yang W, Tian C, Xu H, Wang F, Yang X, Li L, Yang S
Nature communications 2022 Nov 12;13(1):6891
Nature communications 2022 Nov 12;13(1):6891
RAB27A promotes the proliferation and invasion of colorectal cancer cells.
Li Q, Zhao H, Dong W, Guan N, Hu Y, Zeng Z, Zhang H, Zhang F, Li Q, Yang J, Xiao W
Scientific reports 2022 Nov 12;12(1):19359
Scientific reports 2022 Nov 12;12(1):19359
Combination of tolvaptan and valsartan improves cardiac and renal functions in doxorubicin-induced heart failure in mice.
Yan F, Zhu H, He Y, Wu Q, Duan X
European journal of histochemistry : EJH 2022 Nov 11;66(4)
European journal of histochemistry : EJH 2022 Nov 11;66(4)
Dihydrotanshinone I Inhibits the Proliferation and Growth of Oxaliplatin-Resistant Human HCT116 Colorectal Cancer Cells.
Wang M, Xiang Y, Wang R, Zhang L, Zhang H, Chen H, Luan X, Chen L
Molecules (Basel, Switzerland) 2022 Nov 11;27(22)
Molecules (Basel, Switzerland) 2022 Nov 11;27(22)
DJ-1 Protein Inhibits Apoptosis in Cerebral Ischemia by Regulating the Notch1 and Nuclear Factor Erythroid2-Related Factor 2 Signaling Pathways.
Wang T, Xue Y, Li Y, Gao S, Peng L, Zhao Y, Yu S
Neuroscience 2022 Nov 10;504:33-46
Neuroscience 2022 Nov 10;504:33-46
Phosphoproteomics revealed cellular signals immediately responding to disruption of cancer amino acid homeostasis induced by inhibition of L-type amino acid transporter 1.
Okanishi H, Ohgaki R, Xu M, Endou H, Kanai Y
Cancer & metabolism 2022 Nov 10;10(1):18
Cancer & metabolism 2022 Nov 10;10(1):18
KIF17 maintains the epithelial phenotype of breast cancer cells and curbs tumour metastasis.
Li T, Zhai D, Zhang M, Ye R, Kuang X, Shao N, Bi J, Lin Y
Cancer letters 2022 Nov 1;548:215904
Cancer letters 2022 Nov 1;548:215904
HA-ADT suppresses esophageal squamous cell carcinoma progression via apoptosis promotion and autophagy inhibition.
Duan SF, Zhang MM, Zhang X, Liu W, Zhang SH, Yang B, Dong Q, Han JG, Yu HL, Li T, Ji XY, Wu DD, Zhang XJ
Experimental cell research 2022 Nov 1;420(1):113341
Experimental cell research 2022 Nov 1;420(1):113341
Mobilizing phospholipids on tumor plasma membrane implicates phosphatidylserine externalization blockade for cancer immunotherapy.
Wang W, Wu S, Cen Z, Zhang Y, Chen Y, Huang Y, Cillo AR, Prokopec JS, Quarato G, Vignali DAA, Stewart-Ornstein J, Li S, Lu B, Gong YN
Cell reports 2022 Nov 1;41(5):111582
Cell reports 2022 Nov 1;41(5):111582
Effects of apolipoprotein E on regulating insulin sensitivity via regulating insulin receptor signalosome in caveolae.
Liu M, Chen MY, An L, Ma SQ, Mei J, Huang WH, Zhang W
Life sciences 2022 Nov 1;308:120929
Life sciences 2022 Nov 1;308:120929
SIRT4 Expression Ameliorates the Detrimental Effect of Heat Stress via AMPK/mTOR Signaling Pathway in BMECs.
Ding Q, Wang Y, Xia SW, Zhao F, Zhong JF, Wang HL, Chen KL
International journal of molecular sciences 2022 Nov 1;23(21)
International journal of molecular sciences 2022 Nov 1;23(21)
Salidroside protects against osteoporosis in ovariectomized rats by inhibiting oxidative stress and promoting osteogenesis via Nrf2 activation.
Wang YF, Chang YY, Zhang XM, Gao MT, Zhang QL, Li X, Zhang L, Yao WF
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:154020
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:154020
Asperosaponin VI protects mice from sepsis by regulating Hippo and Rho signaling pathway.
Pang C, Wen C, Liang Y, Luo H, Wei L, Liu H, Qin T, Tan H, He C, Liu Y, Chen Y, Zeng S, Zhou C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:154010
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:154010
SiNiSan alleviates liver injury by promoting hepatic stem cell differentiation via Wnt/β-catenin signaling pathway.
Xu W, Du X, Li J, Zhang Z, Ma X, Luo D, Xiao M, Sun Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:153969
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:153969
MiR-1298-5p level downregulation induced by Helicobacter pylori infection inhibits autophagy and promotes gastric cancer development by targeting MAP2K6.
Li X, Zhu M, Zhao G, Zhou A, Min L, Liu S, Zhang N, Zhu S, Guo Q, Zhang S, Li P
Cellular signalling 2022 May;93:110286
Cellular signalling 2022 May;93:110286
MYPT1/PP1-Mediated EZH2 Dephosphorylation at S21 Promotes Epithelial-Mesenchymal Transition in Fibrosis through Control of Multiple Families of Genes.
Zhang L, Wang L, Hu XB, Hou M, Xiao Y, Xiang JW, Xie J, Chen ZG, Yang TH, Nie Q, Fu JL, Wang Y, Zheng SY, Liu YF, Gan YW, Gao Q, Bai YY, Wang JM, Qi RL, Zou M, Ke Q, Zhu XF, Gong L, Liu Y, Li DW
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 May;9(14):e2105539
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 May;9(14):e2105539
Multistage targeting and dual inhibiting strategies based on bioengineered tumor matrix microenvironment-mediated protein nanocages for enhancing cancer biotherapy.
Hu F, Deng C, Zhou Y, Liu Y, Zhang T, Zhang P, Zhao Z, Miao H, Zheng W, Zhang W, Wang M, Ma X
Bioengineering & translational medicine 2022 May;7(2):e10290
Bioengineering & translational medicine 2022 May;7(2):e10290
Macrophage-targeted delivery of siRNA to silence Mecp2 gene expression attenuates pulmonary fibrosis.
Mou Y, Wu GR, Wang Q, Pan T, Zhang L, Xu Y, Xiong W, Zhou Q, Wang Y
Bioengineering & translational medicine 2022 May;7(2):e10280
Bioengineering & translational medicine 2022 May;7(2):e10280
Intracellular hydroxyproline imprinting following resolution of bleomycin-induced pulmonary fibrosis.
Song S, Fu Z, Guan R, Zhao J, Yang P, Li Y, Yin H, Lai Y, Gong G, Zhao S, Yu J, Peng X, He Y, Luo Y, Zhong N, Su J
The European respiratory journal 2022 May;59(5)
The European respiratory journal 2022 May;59(5)
LncRNA LINC00152 promotes oral squamous cell carcinoma growth via enhancing Upstream Transcription Factor 1 mediated Mitochondrial Ribosomal Protein L52 transcription.
Zou X, Hu X, He F, Zhang M, Kong X, Rui S, Liu Y, Wang L, Zheng X, Liu J, Li Z, Luo H
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2022 May;51(5):454-463
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2022 May;51(5):454-463
Absence of TNF Leads to Alternative Activation in Peritoneal Macrophages in Experimental Listeria Monocytogenes Infection.
Li X, Chen C, Zhang L, Cheng X, Geng H, Ji Q, Li C, Chen H, Körner H, Liu X
Immunological investigations 2022 May;51(4):1005-1022
Immunological investigations 2022 May;51(4):1005-1022
Neuregulin-1 regulates the conversion of M1/M2 microglia phenotype via ErbB4-dependent inhibition of the NF-κB pathway.
Ma Y, Fan P, Zhao R, Zhang Y, Wang X, Cui W
Molecular biology reports 2022 May;49(5):3975-3986
Molecular biology reports 2022 May;49(5):3975-3986
27-hydroxycholesterol linked high cholesterol diet to lung adenocarcinoma metastasis.
Li X, Chen H, Zhang L, Chen L, Wei W, Gao S, Xue Q, Li Y, Wang B, Li J, Gao Y, Lin Y
Oncogene 2022 May;41(19):2685-2695
Oncogene 2022 May;41(19):2685-2695
Non-oxidative pentose phosphate pathway controls regulatory T cell function by integrating metabolism and epigenetics.
Liu Q, Zhu F, Liu X, Lu Y, Yao K, Tian N, Tong L, Figge DA, Wang X, Han Y, Li Y, Zhu Y, Hu L, Ji Y, Xu N, Li D, Gu X, Liang R, Gan G, Wu L, Zhang P, Xu T, Hu H, Hu Z, Xu H, Ye D, Yang H, Li B, Tong X
Nature metabolism 2022 May;4(5):559-574
Nature metabolism 2022 May;4(5):559-574
Serpina3c deficiency induced necroptosis promotes non-alcoholic fatty liver disease through β-catenin/Foxo1/TLR4 signaling.
Qian LL, Ji JJ, Jiang Y, Guo JQ, Wu Y, Yang Z, Ma GS, Yao YY
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 May;36(5):e22316
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 May;36(5):e22316
Leonurine inhibits the TXNIP/NLRP3 and NF-κB pathways via Nrf2 activation to alleviate carrageenan-induced pleurisy in mice.
Yan K, Hu J, Hou T, Ci X, Peng L
Phytotherapy research : PTR 2022 May;36(5):2161-2172
Phytotherapy research : PTR 2022 May;36(5):2161-2172
iTRAQ-derived quantitative proteomics uncovers the neuroprotective property of bexarotene in a mice model of cerebral ischemia-reperfusion injury.
Liu H, Wang H, Chen S, Liu S, Tian X, Dong Z, Xu L
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society 2022 May;30(5):585-594
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society 2022 May;30(5):585-594
Schizosaccharomyces pombe Fzo1 is subjected to the ubiquitin-proteasome-mediated degradation during the stationary phase.
Ahmad F, Zhang Y, Yin H, Luo Y, Huang Y
International microbiology : the official journal of the Spanish Society for Microbiology 2022 May;25(2):397-404
International microbiology : the official journal of the Spanish Society for Microbiology 2022 May;25(2):397-404
Cannabidiol inhibits methamphetamine-induced dopamine release via modulation of the DRD1-MeCP2-BDNF-TrkB signaling pathway.
Shen B, Zhang D, Zeng X, Guan L, Yang G, Liu L, Huang J, Li Y, Hong S, Li L
Psychopharmacology 2022 May;239(5):1521-1537
Psychopharmacology 2022 May;239(5):1521-1537
Saccharides from Arctium lappa L. root reduce platelet activation and thrombus formation in a laser injury thrombosis mouse model.
Ruan Y, Ding Y, Li X, Zhang C, Wang M, Liu M, Wang L, Xing J, Hu L, Zhao X, Ding Z, Dong J, Liu Y
Experimental and therapeutic medicine 2022 May;23(5):344
Experimental and therapeutic medicine 2022 May;23(5):344
2-Deoxy-D-glucose increases the sensitivity of glioblastoma cells to BCNU through the regulation of glycolysis, ROS and ERS pathways: In vitro and in vivo validation.
Sun X, Fan T, Sun G, Zhou Y, Huang Y, Zhang N, Zhao L, Zhong R, Peng Y
Biochemical pharmacology 2022 May;199:115029
Biochemical pharmacology 2022 May;199:115029
Urea transporter B downregulates polyamines levels in melanoma B16 cells via p53 activation.
Li J, Sun Y, Yan R, Wu X, Zou H, Meng Y
Biochimica et biophysica acta. Molecular cell research 2022 May;1869(5):119236
Biochimica et biophysica acta. Molecular cell research 2022 May;1869(5):119236
A53T α-synuclein induces neurogenesis impairment and cognitive dysfunction in line M83 transgenic mice and reduces the proliferation of embryonic neural stem cells.
Zhang Y, Wu Q, Ren Y, Zhang Y, Feng L
Brain research bulletin 2022 May;182:118-129
Brain research bulletin 2022 May;182:118-129
Pseudorabies virus tegument protein UL13 recruits RNF5 to inhibit STING-mediated antiviral immunity.
Kong Z, Yin H, Wang F, Liu Z, Luan X, Sun L, Liu W, Shang Y
PLoS pathogens 2022 May;18(5):e1010544
PLoS pathogens 2022 May;18(5):e1010544
MEF2D-NR4A1-FAM134B2-mediated reticulophagy contributes to amino acid homeostasis.
Shiozaki Y, Miyazaki-Anzai S, Keenan AL, Miyazaki M
Autophagy 2022 May;18(5):1049-1061
Autophagy 2022 May;18(5):1049-1061
M1-type microglia can induce astrocytes to deposit chondroitin sulfate proteoglycan after spinal cord injury.
Yu SS, Li ZY, Xu XZ, Yao F, Luo Y, Liu YC, Cheng L, Zheng MG, Jing JH
Neural regeneration research 2022 May;17(5):1072-1079
Neural regeneration research 2022 May;17(5):1072-1079
Recombinant P40 protein of Schistosoma japonicum inhibits TREM-1 expression in RAW264.7 cells via FOXO3a.
Shen P, Zhang T, Chen G, Zhang B, Huang A, Duan L, Zhu D, Chen J, Wang J, Duan Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 May;149:112826
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 May;149:112826
Remote cyclic compression ameliorates myocardial infarction injury in rats via AMPK-dependent pathway.
Xu S, Xia X, Liu Y, Chen F, Gu R, Bian X, Xu X, Jia C, Lu S, Gu Y, Bai H, Zhang H
Microvascular research 2022 May;141:104313
Microvascular research 2022 May;141:104313
Transformer 2 alpha homolog is a downstream gene of hypoxia-inducible factor 1 subunit alpha and is involved in the progression of pancreatic cancer.
Cao W, Lei S, Zeng Z, Xiao C, Sun B, Xie P, Li Y, Luo D, Yu W
Bioengineered 2022 May;13(5):13238-13251
Bioengineered 2022 May;13(5):13238-13251
Dihydroartemisinin alleviates steatosis and inflammation in nonalcoholic steatohepatitis by decreasing endoplasmic reticulum stress and oxidative stress.
Li T, Chen Y, Tan P, Shi H, Huang Z, Cai T, Cheng Y, Du Y, Fu W
Bioorganic chemistry 2022 May;122:105737
Bioorganic chemistry 2022 May;122:105737
GM1 ganglioside modifies microglial and neuroinflammatory responses to α-synuclein in the rat AAV-A53T α-synuclein model of Parkinson's disease.
Schneider JS, Singh G, Williams CK, Singh V
Molecular and cellular neurosciences 2022 May;120:103729
Molecular and cellular neurosciences 2022 May;120:103729
Targeting DCLK1 overcomes 5-fluorouracil resistance in colorectal cancer through inhibiting CCAR1/β-catenin pathway-mediated cancer stemness.
Wang L, Zhao L, Lin Z, Yu D, Jin M, Zhou P, Ren J, Cheng J, Yang K, Wu G, Zhang T, Zhang D
Clinical and translational medicine 2022 May;12(5):e743
Clinical and translational medicine 2022 May;12(5):e743
Ckip-1 Mediates P. gingivalis-Suppressed Cementoblast Mineralization.
Huang X, Ma L, Wang X, Wang H, Peng Y, Gao X, Huang H, Chen Y, Zhang Y, Cao Z
Journal of dental research 2022 May;101(5):599-608
Journal of dental research 2022 May;101(5):599-608
Identification of oleoylethanolamide as an endogenous ligand for HIF-3α.
Diao X, Ye F, Zhang M, Ren X, Tian X, Lu J, Sun X, Hou Z, Chen X, Li F, Zhuang J, Ding H, Peng C, Rastinejad F, Luo C, Wu D
Nature communications 2022 May 9;13(1):2529
Nature communications 2022 May 9;13(1):2529
Forkhead Box q1 promotes invasion and metastasis in colorectal cancer by activating the epidermal growth factor receptor pathway.
Zhang JJ, Cao CX, Wan LL, Zhang W, Liu ZJ, Wang JL, Guo Q, Tang H
World journal of gastroenterology 2022 May 7;28(17):1781-1797
World journal of gastroenterology 2022 May 7;28(17):1781-1797
Mitochondrial apolipoprotein A-I binding protein alleviates atherosclerosis by regulating mitophagy and macrophage polarization.
Duan M, Chen H, Yin L, Zhu X, Novák P, Lv Y, Zhao G, Yin K
Cell communication and signaling : CCS 2022 May 7;20(1):60
Cell communication and signaling : CCS 2022 May 7;20(1):60
BIN1 is a key regulator of proinflammatory and neurodegeneration-related activation in microglia.
Sudwarts A, Ramesha S, Gao T, Ponnusamy M, Wang S, Hansen M, Kozlova A, Bitarafan S, Kumar P, Beaulieu-Abdelahad D, Zhang X, Collier L, Szekeres C, Wood LB, Duan J, Thinakaran G, Rangaraju S
Molecular neurodegeneration 2022 May 7;17(1):33
Molecular neurodegeneration 2022 May 7;17(1):33
Small Extracellular Vesicles Containing miR-34c Derived from Bone Marrow Mesenchymal Stem Cells Regulates Epithelial Sodium Channel via Targeting MARCKS.
Hua Y, Han A, Yu T, Hou Y, Ding Y, Nie H
International journal of molecular sciences 2022 May 6;23(9)
International journal of molecular sciences 2022 May 6;23(9)
Combination of berberine and low glucose inhibits gastric cancer through the PP2A/GSK3β/MCL-1 signaling pathway.
Peng Z, Wangmu T, Li L, Han G, Huang D, Yi P
European journal of pharmacology 2022 May 5;922:174918
European journal of pharmacology 2022 May 5;922:174918
CCDC50 suppresses NLRP3 inflammasome activity by mediating autophagic degradation of NLRP3.
Lin Y, Li Z, Wang Y, Tian T, Jia P, Ye Y, He M, Yang Z, Li C, Guo D, Hou P
EMBO reports 2022 May 4;23(5):e54453
EMBO reports 2022 May 4;23(5):e54453
Targeted delivery of fat extract by platelet membrane-cloaked nanocarriers for the treatment of ischemic stroke.
Wang C, Yang X, Jiang Y, Qi L, Zhuge D, Xu T, Guo Y, Deng M, Zhang W, Tian D, Yin Q, Li L, Zhang Z, Wang Y, Yang GY, Chen Y, Tang Y
Journal of nanobiotechnology 2022 May 31;20(1):249
Journal of nanobiotechnology 2022 May 31;20(1):249
Maternal Prenatal Inflammation Increases Brain Damage Susceptibility of Lipopolysaccharide in Adult Rat Offspring via COX-2/PGD-2/DPs Pathway Activation.
Zhang J, Yao P, Han W, Luo Y, Li Y, Yang Y, Xia H, Chen Z, Chen Q, Wang H, Yang L, Li H, Hu C, Huang H, Peng Z, Tan X, Li M, Yang J
International journal of molecular sciences 2022 May 30;23(11)
International journal of molecular sciences 2022 May 30;23(11)
SM22α-lineage niche cells regulate intramembranous bone regeneration via PDGFRβ-triggered hydrogen sulfide production.
Zhou X, Liu J, Zheng Y, Zhang Z, Wu Y, Yang W, Liu J, Huang Y, Yi Y, Zhao Z, Xiao H, Mo X, Wang J
Cell reports 2022 May 3;39(5):110750
Cell reports 2022 May 3;39(5):110750
DNA methylation of miR-138 regulates cell proliferation and EMT in cervical cancer by targeting EZH2.
Chen R, Gan Q, Zhao S, Zhang D, Wang S, Yao L, Yuan M, Cheng J
BMC cancer 2022 May 3;22(1):488
BMC cancer 2022 May 3;22(1):488
Therapeutic strategies targeting uPAR potentiate anti-PD-1 efficacy in diffuse-type gastric cancer.
Qin L, Wang L, Zhang J, Zhou H, Yang Z, Wang Y, Cai W, Wen F, Jiang X, Zhang T, Ye H, Long B, Qin J, Shi W, Guan X, Yu Z, Yang J, Wang Q, Jiao Z
Science advances 2022 May 27;8(21):eabn3774
Science advances 2022 May 27;8(21):eabn3774
Novel dual-targeting c-Myc inhibitor D347-2761 represses myeloma growth via blocking c-Myc/Max heterodimerization and disturbing its stability.
Yao R, Zhang M, Zhou J, Liu L, Zhang Y, Gao J, Xu K
Cell communication and signaling : CCS 2022 May 26;20(1):73
Cell communication and signaling : CCS 2022 May 26;20(1):73
TARDBP Inhibits Porcine Epidemic Diarrhea Virus Replication through Degrading Viral Nucleocapsid Protein and Activating Type I Interferon Signaling.
Dong S, Kong N, Zhang Y, Li Y, Sun D, Qin W, Zhai H, Zhai X, Yang X, Ye C, Ye M, Liu C, Yu L, Zheng H, Tong W, Yu H, Zhang W, Tong G, Shan T
Journal of virology 2022 May 25;96(10):e0007022
Journal of virology 2022 May 25;96(10):e0007022
Aberrant methylmalonylation underlies methylmalonic acidemia and is attenuated by an engineered sirtuin.
Head PE, Myung S, Chen Y, Schneller JL, Wang C, Duncan N, Hoffman P, Chang D, Gebremariam A, Gucek M, Manoli I, Venditti CP
Science translational medicine 2022 May 25;14(646):eabn4772
Science translational medicine 2022 May 25;14(646):eabn4772
Role of Nrf2 Nucleus Translocation in Beauvericin-Induced Cell Damage in Rat Hepatocytes.
Shi J, Wang Y, Xu W, Cai G, Zou H, Yuan Y, Gu J, Liu Z, Bian J
Toxins 2022 May 25;14(6)
Toxins 2022 May 25;14(6)
Melatonin Alleviates Oxidative Stress Induced by H(2)O(2) in Porcine Trophectoderm Cells.
Fu Y, Chen Y, Jin Z, Gao H, Song G, Wang Q, Xu K
Antioxidants (Basel, Switzerland) 2022 May 25;11(6)
Antioxidants (Basel, Switzerland) 2022 May 25;11(6)
Four AAs increase DMT1 abundance in duodenal brush-border membrane vesicles and enhance iron absorption in iron-deprived mice.
Woloshun RR, Yu Y, Xu X, Lee JK, Zhu S, Shine JS, Ebea P, Stevens BR, Vidyasagar S, Collins JF
Blood advances 2022 May 24;6(10):3011-3021
Blood advances 2022 May 24;6(10):3011-3021
Antibiotic pretreatment attenuates liver ischemia-reperfusion injury by Farnesoid X receptor activation.
Liu H, Wang J, Ding Y, Shi X, Ren H
Cell death & disease 2022 May 21;13(5):484
Cell death & disease 2022 May 21;13(5):484
Premature translation termination mediated non-ER stress induced ATF6 activation by a ligand-dependent ribosomal frameshifting circuit.
Hsu HT, Murata A, Dohno C, Nakatani K, Chang K
Nucleic acids research 2022 May 20;50(9):5369-5383
Nucleic acids research 2022 May 20;50(9):5369-5383
[P4HA2 promotes occurrence and progression of liver cancer by regulating the PI3K/Akt/mTOR signaling pathway].
Shang L, Jiang W, Zhang J, Wu W
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2022 May 20;42(5):665-672
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2022 May 20;42(5):665-672
Overexpressed p-S6 associates with lymph node metastasis and predicts poor prognosis in non-small cell lung cancer.
Tang Y, Luo J, Zhou Y, Zang H, Yang Y, Liu S, Zheng H, Ma J, Fan S, Wen Q
BMC cancer 2022 May 20;22(1):564
BMC cancer 2022 May 20;22(1):564
Inhibition of the CDK2 and Cyclin A complex leads to autophagic degradation of CDK2 in cancer cells.
Zhang J, Gan Y, Li H, Yin J, He X, Lin L, Xu S, Fang Z, Kim BW, Gao L, Ding L, Zhang E, Ma X, Li J, Li L, Xu Y, Horne D, Xu R, Yu H, Gu Y, Huang W
Nature communications 2022 May 20;13(1):2835
Nature communications 2022 May 20;13(1):2835
Microarray Profiling and Co-Expression Network Analysis of LncRNAs and mRNAs in Acute Respiratory Distress Syndrome Mouse Model.
Wu X, Ma C, Ma Q, Zhuang P, Deng G
Pathogens (Basel, Switzerland) 2022 May 2;11(5)
Pathogens (Basel, Switzerland) 2022 May 2;11(5)
Cystathionine-β-synthase (CBS)/H2S system promotes lymph node metastasis of esophageal squamous cell carcinoma (ESCC) by activating SIRT1.
Liu Y, Pan L, Li Y, Deng Y, Han X, Fu H, Wang T
Carcinogenesis 2022 May 19;43(4):382-392
Carcinogenesis 2022 May 19;43(4):382-392
Antisense oligonucleotides targeting the SMN2 promoter region enhance SMN2 expression in spinal muscular atrophy cell lines and mouse model.
Wang J, Bai J, OuYang S, Wang H, Jin Y, Peng X, Ge X, Jiao H, Zou J, He C, Xiao P, Song F, Qu Y
Human molecular genetics 2022 May 19;31(10):1635-1650
Human molecular genetics 2022 May 19;31(10):1635-1650
Downregulation of lncRNA Miat contributes to the protective effect of electroacupuncture against myocardial fibrosis.
Qi W, Li X, Ren Y, Liu X, Fu H, Wang X, Li X, Xiong J, Zheng Q, Cai D, Liang F
Chinese medicine 2022 May 17;17(1):57
Chinese medicine 2022 May 17;17(1):57
BMP4 Exerts Anti-Neurogenic Effect via Inducing Id3 during Aging.
Li T, Liu H, Jiang D, Yang K, Shen J, Feng H, Wang S, Zhang Y, Wang Y, Tang TS
Biomedicines 2022 May 17;10(5)
Biomedicines 2022 May 17;10(5)
TMCO1 expression promotes cell proliferation and induces epithelial-mesenchymal transformation in human gliomas.
Gao L, Ye Z, Liu JH, Yang JA, Li Y, Cai JY, Wang YX, Tong SA, Deng G, Zhang S, Chen QX
Medical oncology (Northwood, London, England) 2022 May 15;39(5):90
Medical oncology (Northwood, London, England) 2022 May 15;39(5):90
Induction of p27 contributes to inhibitory effect of isorhapontigenin (ISO) on malignant transformation of human urothelial cells.
Huang M, Hua X, Xu J, Tian Z, Wang J, Chen H, Wang X, Shu P, Ye H, Shu J, Huang C
Cell cycle (Georgetown, Tex.) 2022 May 15;:1-14
Cell cycle (Georgetown, Tex.) 2022 May 15;:1-14
Induction of COX-2 by feline calicivirus via activation of the MEK1-ERK1/2 pathway, and attenuation of feline lung inflammation and injury by MEK1 inhibitor AZD6244 (selumetinib).
Liu Y, Shi WD, Xie QQ, Wang JG, Gu CC, Ji ZH, Xiao J, Liu WQ
Biochemical and biophysical research communications 2022 May 14;604:8-13
Biochemical and biophysical research communications 2022 May 14;604:8-13
Infectious Bronchitis Virus Nsp14 Degrades JAK1 to Inhibit the JAK-STAT Signaling Pathway in HD11 Cells.
Ma P, Gu K, Li H, Zhao Y, Li C, Wen R, Zhou C, Lei C, Yang X, Wang H
Viruses 2022 May 14;14(5)
Viruses 2022 May 14;14(5)
Hsa_circ_0000345 inhibits cell proliferation, migration and invasion of nasopharyngeal carcinoma cells via miR-513a-3p/PTEN axis.
Jiang C, Li H, Liu F, Shi L, Liu J, Li Y
The journal of physiological sciences : JPS 2022 May 12;72(1):10
The journal of physiological sciences : JPS 2022 May 12;72(1):10
Human epididymis protein 4 aggravates airway inflammation and remodeling in chronic obstructive pulmonary disease.
Zhan Y, Chen J, Wu J, Gu Y, Huang Q, Deng Z, Chen S, Wu X, Lv Y, Zeng Z, Xie J
Respiratory research 2022 May 12;23(1):120
Respiratory research 2022 May 12;23(1):120
Pu-erh Tea Restored Circadian Rhythm Disruption by Regulating Tryptophan Metabolism.
Hu S, Luo L, Bian X, Liu RH, Zhao S, Chen Y, Sun K, Jiang J, Liu Z, Zeng L
Journal of agricultural and food chemistry 2022 May 11;70(18):5610-5623
Journal of agricultural and food chemistry 2022 May 11;70(18):5610-5623
Temporal Dynamics of the Ruminant Type I IFN-Induced Antiviral State against Homologous Parainfluenza Virus 3 Challenge In Vitro.
Sun M, Hao F, Li W, Cheng Z, Zhang W, Yang L, Mao L, Liu M
Viruses 2022 May 11;14(5)
Viruses 2022 May 11;14(5)
TGR5 Agonist INT-777 Alleviates Inflammatory Neurodegeneration in Parkinson's Disease Mouse Model by Modulating Mitochondrial Dynamics in Microglia.
Huang R, Gao Y, Chen J, Duan Q, He P, Zhang J, Huang H, Zhang Q, Ma G, Zhang Y, Nie K, Wang L
Neuroscience 2022 May 10;490:100-119
Neuroscience 2022 May 10;490:100-119
Effect of 1-Deoxynojirimycin on insulin resistance in prediabetic mice based on next-generation sequencing and intestinal microbiota study.
Ren X, Xing Y, He L, Xiu Z, Yang L, Han A, Jia Q, Dong Y
Journal of ethnopharmacology 2022 May 10;289:115029
Journal of ethnopharmacology 2022 May 10;289:115029
P-Coumaric Acid Reverses Depression-Like Behavior and Memory Deficit Via Inhibiting AGE-RAGE-Mediated Neuroinflammation.
Yu XD, Zhang D, Xiao CL, Zhou Y, Li X, Wang L, He Z, Reilly J, Xiao ZY, Shu X
Cells 2022 May 10;11(10)
Cells 2022 May 10;11(10)
Hepatokine ERAP1 Disturbs Skeletal Muscle Insulin Sensitivity Via Inhibiting USP33-Mediated ADRB2 Deubiquitination.
Niu Y, Jiang H, Yin H, Wang F, Hu R, Hu X, Peng B, Shu Y, Li Z, Chen S, Guo F
Diabetes 2022 May 1;71(5):921-933
Diabetes 2022 May 1;71(5):921-933
Design, synthesis and activity study of a novel PI3K degradation by hijacking VHL E3 ubiquitin ligase.
Wang H, Li C, Liu X, Ma M
Bioorganic & medicinal chemistry 2022 May 1;61:116707
Bioorganic & medicinal chemistry 2022 May 1;61:116707
Curcumin protects against manganese-induced neurotoxicity in rat by regulating oxidative stress-related gene expression via H3K27 acetylation.
Yang Y, Liu Y, Zhang AL, Tang SF, Ming Q, Ao CY, Liu Y, Li CZ, Yu C, Zhao H, Chen L, Li J
Ecotoxicology and environmental safety 2022 May 1;236:113469
Ecotoxicology and environmental safety 2022 May 1;236:113469
Fabrication of SA/Gel/C scaffold with 3D bioprinting to generate micro-nano porosity structure for skin wound healing: a detailed animal in vivo study.
Niu C, Wang L, Ji D, Ren M, Ke D, Fu Q, Zhang K, Yang X
Cell regeneration (London, England) 2022 May 1;11(1):10
Cell regeneration (London, England) 2022 May 1;11(1):10
Injectable self-healing hydrogel with siRNA delivery property for sustained STING silencing and enhanced therapy of intervertebral disc degeneration.
Chen J, Zhu H, Zhu Y, Zhao C, Wang S, Zheng Y, Xie Z, Jin Y, Song H, Yang L, Zhang J, Dai J, Hu Z, Wang H
Bioactive materials 2022 Mar;9:29-43
Bioactive materials 2022 Mar;9:29-43
Role of Lysocardiolipin Acyltransferase in Cigarette Smoke-Induced Lung Epithelial Cell Mitochondrial ROS, Mitochondrial Dynamics, and Apoptosis.
Bandela M, Suryadevara V, Fu P, Reddy SP, Bikkavilli K, Huang LS, Dhavamani S, Subbaiah PV, Singla S, Dudek SM, Ware LB, Ramchandran R, Natarajan V
Cell biochemistry and biophysics 2022 Mar;80(1):203-216
Cell biochemistry and biophysics 2022 Mar;80(1):203-216
Circular RNA PVT1 inhibits tendon stem/progenitor cell senescence by sponging microRNA-199a-5p.
Han W, Tao X, Weng T, Chen L
Toxicology in vitro : an international journal published in association with BIBRA 2022 Mar;79:105297
Toxicology in vitro : an international journal published in association with BIBRA 2022 Mar;79:105297
Dysregulated lipid metabolism blunts the sensitivity of cancer cells to EZH2 inhibitor.
Zhang T, Guo Z, Huo X, Gong Y, Li C, Huang J, Wang Y, Feng H, Ma X, Jiang C, Yin Q, Xue L
EBioMedicine 2022 Mar;77:103872
EBioMedicine 2022 Mar;77:103872
Long Non-coding Antisense RNA DDIT4-AS1 Regulates Meningitic Escherichia coli-Induced Neuroinflammation by Promoting DDIT4 mRNA Stability.
Yang B, Xu B, Yang R, Fu J, Li L, Huo D, Chen J, Yang X, Tan C, Chen H, Wang X
Molecular neurobiology 2022 Mar;59(3):1351-1365
Molecular neurobiology 2022 Mar;59(3):1351-1365
XBP1s promotes the development of lung adenocarcinoma via the p‑JNK MAPK pathway.
Jiang H, Jiang Q, He Y, Li X, Xu Y, Liu X
International journal of molecular medicine 2022 Mar;49(3)
International journal of molecular medicine 2022 Mar;49(3)
Epac activation ameliorates tubulointerstitial inflammation in diabetic nephropathy.
Yang WX, Liu Y, Zhang SM, Wang HF, Liu YF, Liu JL, Li XH, Zeng MR, Han YZ, Liu FY, Sun L, Xiao L
Acta pharmacologica Sinica 2022 Mar;43(3):659-671
Acta pharmacologica Sinica 2022 Mar;43(3):659-671
YTHDF2 promotes multiple myeloma cell proliferation via STAT5A/MAP2K2/p-ERK axis.
Hua Z, Wei R, Guo M, Lin Z, Yu X, Li X, Gu C, Yang Y
Oncogene 2022 Mar;41(10):1482-1491
Oncogene 2022 Mar;41(10):1482-1491
Nicotinamide N-methyltransferase ameliorates renal fibrosis by its metabolite 1-methylnicotinamide inhibiting the TGF-β1/Smad3 pathway.
Zhang W, Rong G, Gu J, Fan C, Guo T, Jiang T, Deng W, Xie J, Su Z, Yu Q, Mai J, Zheng R, Chen X, Tang X, Zhang J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Mar;36(3):e22084
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Mar;36(3):e22084
Ornithine decarboxylase of the fungal pathogen Colletotrichum higginsianum plays an important role in regulating global metabolic pathways and virulence.
Yan Y, Tang J, Yuan Q, Liu H, Huang J, Hsiang T, Bao C, Zheng L
Environmental microbiology 2022 Mar;24(3):1093-1116
Environmental microbiology 2022 Mar;24(3):1093-1116
Proteomic analysis reveals that Xbp1s promotes hypoxic pulmonary hypertension through the p-JNK MAPK pathway.
Jiang H, Niu Y, He Y, Li X, Xu Y, Liu X
Journal of cellular physiology 2022 Mar;237(3):1948-1963
Journal of cellular physiology 2022 Mar;237(3):1948-1963
Role of SLC39A6 in the development and progression of liver cancer.
Wan Z, Wang X
Oncology letters 2022 Mar;23(3):77
Oncology letters 2022 Mar;23(3):77
Cordycepin prevents and ameliorates experimental autoimmune encephalomyelitis by inhibiting leukocyte infiltration and reducing neuroinflammation.
Song YC, Liu CT, Lee HJ, Yen HR
Biochemical pharmacology 2022 Mar;197:114918
Biochemical pharmacology 2022 Mar;197:114918
Chk1 Inhibition Ameliorates Alzheimer's Disease Pathogenesis and Cognitive Dysfunction Through CIP2A/PP2A Signaling.
Hu W, Wang Z, Zhang H, Mahaman YAR, Huang F, Meng D, Zhou Y, Wang S, Jiang N, Xiong J, Westermarck J, Lu Y, Wang J, Wang X, Shentu Y, Liu R
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2022 Mar;19(2):570-591
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2022 Mar;19(2):570-591
LPS Activated Macrophages Induced Hepatocyte Pyroptosis via P2X7R Activation of NLRP3 in Mice.
Luo L, Fang Y, Yuan Q, Liao J, Zhang Z
Iranian journal of immunology : IJI 2022 Mar;19(1):4
Iranian journal of immunology : IJI 2022 Mar;19(1):4
DECR1 directly activates HSL to promote lipolysis in cervical cancer cells.
Zhou H, Zhang J, Yan Z, Qu M, Zhang G, Han J, Wang F, Sun K, Wang L, Yang X
Biochimica et biophysica acta. Molecular and cell biology of lipids 2022 Mar;1867(3):159090
Biochimica et biophysica acta. Molecular and cell biology of lipids 2022 Mar;1867(3):159090
C19orf12 ablation causes ferroptosis in mitochondrial membrane protein-associated with neurodegeneration.
Shao C, Zhu J, Ma X, Siedlak SL, Cohen ML, Lerner A, Wang W
Free radical biology & medicine 2022 Mar;182:23-33
Free radical biology & medicine 2022 Mar;182:23-33
Maintaining homeostasis of mitochondria and endoplasmic reticulum with NSC228155 alleviates cisplatin-induced acute kidney injury.
Li Y, Jiang Y, Zhou W, Wu Y, Zhang S, Ding G, Zhang Y, Zhang A, Huang S, Jia Z, You R
Free radical biology & medicine 2022 Mar;181:270-287
Free radical biology & medicine 2022 Mar;181:270-287
ROS-responsive nanoparticles for oral delivery of luteolin and targeted therapy of ulcerative colitis by regulating pathological microenvironment.
Tan C, Fan H, Ding J, Han C, Guan Y, Zhu F, Wu H, Liu Y, Zhang W, Hou X, Tan S, Tang Q
Materials today. Bio 2022 Mar;14:100246
Materials today. Bio 2022 Mar;14:100246
In situ injectable hydrogel-loaded drugs induce anti-tumor immune responses in melanoma immunochemotherapy.
Li J, Luo G, Zhang C, Long S, Guo L, Yang G, Wang F, Zhang L, Shi L, Fu Y, Zhang Y
Materials today. Bio 2022 Mar;14:100238
Materials today. Bio 2022 Mar;14:100238
MiR-7-5p suppresses invasion via downregulation of the autophagy-related gene ATG7 and increases chemoresistance to cisplatin in BCa.
Wang C, Tang Z, Zhang Z, Liu T, Zhang J, Huang H, Li Y
Bioengineered 2022 Mar;13(3):7328-7339
Bioengineered 2022 Mar;13(3):7328-7339
Divergence of Tbx4 hindlimb enhancer HLEA underlies the hindlimb loss during cetacean evolution.
Liang N, Deme L, Kong Q, Sun L, Cao Y, Wu T, Huang X, Xu S, Yang G
Genomics 2022 Mar;114(2):110292
Genomics 2022 Mar;114(2):110292
Anti-PD-L1 antibody alleviates pulmonary fibrosis by inducing autophagy via inhibition of the PI3K/Akt/mTOR pathway.
Lu Y, Zhong W, Liu Y, Chen W, Zhang J, Zeng Z, Huang H, Qiao Y, Wan X, Meng X, Cai S, Dong H
International immunopharmacology 2022 Mar;104:108504
International immunopharmacology 2022 Mar;104:108504
Myricetin exerts its antiviral activity against infectious bronchitis virus by inhibiting the deubiquitinating activity of papain-like protease.
Peng S, Fang C, He H, Song X, Zhao X, Zou Y, Li L, Jia R, Yin Z
Poultry science 2022 Mar;101(3):101626
Poultry science 2022 Mar;101(3):101626
Cinnamomi Ramulus inhibits the growth of colon cancer cells via Akt/ERK signaling pathways.
Pan B, Xia Y, Gao Z, Zhao G, Wang L, Fang S, Liu L, Yan S
Chinese medicine 2022 Mar 9;17(1):36
Chinese medicine 2022 Mar 9;17(1):36
Implications of miR-148a-3p/p35/PTEN signaling in tau hyperphosphorylation and autoregulatory feedforward of Akt/CREB in Alzheimer's disease.
Zeng L, Jiang H, Ashraf GM, Liu J, Wang L, Zhao K, Liu M, Li Z, Liu R
Molecular therapy. Nucleic acids 2022 Mar 8;27:256-275
Molecular therapy. Nucleic acids 2022 Mar 8;27:256-275
Highly efficient A-to-G base editing by ABE8.17 in rabbits.
Zhao D, Qian Y, Li J, Li Z, Lai L
Molecular therapy. Nucleic acids 2022 Mar 8;27:1156-1163
Molecular therapy. Nucleic acids 2022 Mar 8;27:1156-1163
LncRNA PVT1 promotes tumorigenesis of glioblastoma by recruiting COPS5 to deubiquitinate and stabilize TRIM24.
Lv T, Jin Y, Miao Y, Xu T, Jia F, Feng H, Zhang X
Molecular therapy. Nucleic acids 2022 Mar 8;27:109-121
Molecular therapy. Nucleic acids 2022 Mar 8;27:109-121
Hyperglycemia Promotes Endothelial Cell Senescence through AQR/PLAU Signaling Axis.
Wan Y, Liu Z, Wu A, Khan AH, Zhu Y, Ding S, Li X, Zhao Y, Dai X, Zhou J, Liu J, Li Y, Gong X, Liu M, Tian XL
International journal of molecular sciences 2022 Mar 7;23(5)
International journal of molecular sciences 2022 Mar 7;23(5)
RETRACTED: PINK1 deficiency in gastric cancer compromises mitophagy, promotes the Warburg effect, and facilitates M2 polarization of macrophages.
Xu Y, Lu J, Tang Y, Xie W, Zhang H, Wang B, Zhang S, Hou W, Zou C, Jiang P, Zhang W
Cancer letters 2022 Mar 31;529:19-36
Cancer letters 2022 Mar 31;529:19-36
Regulation of chromatin accessibility by hypoxia and HIF.
Batie M, Frost J, Shakir D, Rocha S
The Biochemical journal 2022 Mar 31;479(6):767-786
The Biochemical journal 2022 Mar 31;479(6):767-786
Skin epithelial cells change their mechanics and proliferation upon snail-mediated EMT signalling.
Hosseini K, Trus P, Frenzel A, Werner C, Fischer-Friedrich E
Soft matter 2022 Mar 30;18(13):2585-2596
Soft matter 2022 Mar 30;18(13):2585-2596
The SETD8/ELK1/bach1 complex regulates hyperglycaemia-mediated EndMT in diabetic nephropathy.
Li X, Lu L, Hou W, Wang F, Huang T, Meng Z, Zhu M
Journal of translational medicine 2022 Mar 29;20(1):147
Journal of translational medicine 2022 Mar 29;20(1):147
Construction of a Recombinant Japanese Encephalitis Virus with a Hemagglutinin-Tagged NS2A: A Model for an Analysis of Biological Characteristics and Functions of NS2A during Viral Infection.
Ma X, Li C, Xia Q, Zhang Y, Yang Y, Wahaab A, Liu K, Li Z, Li B, Qiu Y, Wei J, Ma Z
Viruses 2022 Mar 29;14(4)
Viruses 2022 Mar 29;14(4)
SETD8 cooperates with MZF1 to participate in hyperglycemia-induced endothelial inflammation via elevation of WNT5A levels in diabetic nephropathy.
Wang F, Hou W, Li X, Lu L, Huang T, Zhu M, Miao C
Cellular & molecular biology letters 2022 Mar 26;27(1):30
Cellular & molecular biology letters 2022 Mar 26;27(1):30
TGF-β1-induced RAP2 regulates invasion in pancreatic cancer.
Jin K, Liu C, Cheng H, Fei Q, Huang Q, Xiao Z, Yu X, Wu W
Acta biochimica et biophysica Sinica 2022 Mar 25;54(3):361-369
Acta biochimica et biophysica Sinica 2022 Mar 25;54(3):361-369
Highland barley Monascus purpureus Went extract ameliorates high-fat, high-fructose, high-cholesterol diet induced nonalcoholic fatty liver disease by regulating lipid metabolism in golden hamsters.
Zhao CZ, Jiang W, Zhu YY, Wang CZ, Zhong WH, Wu G, Chen J, Zhu MN, Wu QL, Du XL, Luo YY, Li M, Wang HL, Zhao H, Ma QG, Zhong GY, Wei RR
Journal of ethnopharmacology 2022 Mar 25;286:114922
Journal of ethnopharmacology 2022 Mar 25;286:114922
WWOX-Mediated Degradation of AMOTp130 Negatively Affects Egress of Filovirus VP40 Virus-Like Particles.
Liang J, Ruthel G, Freedman BD, Harty RN
Journal of virology 2022 Mar 23;96(6):e0202621
Journal of virology 2022 Mar 23;96(6):e0202621
Long noncoding RNA Gm31629 protects against mucosal damage in experimental colitis via YB-1/E2F pathway.
Feng X, Xiao Y, He J, Yang M, Guo Q, Su T, Huang Y, Yi J, Li CJ, Luo XH, Liu XW, Zhou HY
JCI insight 2022 Mar 22;7(6)
JCI insight 2022 Mar 22;7(6)
NAD(+) Anabolism Disturbance Causes Glomerular Mesangial Cell Injury in Diabetic Nephropathy.
Li X, Li Y, Li F, Chen Q, Zhao Z, Liu X, Zhang N, Li H
International journal of molecular sciences 2022 Mar 22;23(7)
International journal of molecular sciences 2022 Mar 22;23(7)
Peroxidase-like Active Nanomedicine with Dual Glutathione Depletion Property to Restore Oxaliplatin Chemosensitivity and Promote Programmed Cell Death.
Wu F, Du Y, Yang J, Shao B, Mi Z, Yao Y, Cui Y, He F, Zhang Y, Yang P
ACS nano 2022 Mar 22;16(3):3647-3663
ACS nano 2022 Mar 22;16(3):3647-3663
Co-delivery of EGCG and lycopene via a pickering double emulsion induced synergistic hypolipidemic effect.
Wang Q, Wang L, Abdullah, Tian W, Song M, Cao Y, Xiao J
Food & function 2022 Mar 21;13(6):3419-3430
Food & function 2022 Mar 21;13(6):3419-3430
Ascorbic acid 2-glucoside preconditioning enhances the ability of bone marrow mesenchymal stem cells in promoting wound healing.
Yi Y, Wu M, Zhou X, Xiong M, Tan Y, Yu H, Liu Z, Wu Y, Zhang Q
Stem cell research & therapy 2022 Mar 21;13(1):119
Stem cell research & therapy 2022 Mar 21;13(1):119
Folic Acid-Modified Fluorescent-Magnetic Nanoparticles for Efficient Isolation and Identification of Circulating Tumor Cells in Ovarian Cancer.
Pan Y, Wang Z, Ma J, Zhou T, Wu Z, Ding P, Sun N, Liu L, Pei R, Zhu W
Biosensors 2022 Mar 21;12(3)
Biosensors 2022 Mar 21;12(3)
lncRNA HITT inhibits metastasis by attenuating Rab5-mediated endocytosis in lung adenocarcinoma.
Wang X, Zheng S, Yang F, Zhang W, Zhao D, Xue X, Lin Q, He Y, Hu G, Hu Y
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Mar 2;30(3):1071-1088
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Mar 2;30(3):1071-1088
An advanced network pharmacology study to explore the novel molecular mechanism of Compound Kushen Injection for treating hepatocellular carcinoma by bioinformatics and experimental verification.
Lu S, Meng Z, Tan Y, Wu C, Huang Z, Huang J, Fu C, Stalin A, Guo S, Liu X, You L, Li X, Zhang J, Zhou W, Zhang X, Wang M, Wu J
BMC complementary medicine and therapies 2022 Mar 2;22(1):54
BMC complementary medicine and therapies 2022 Mar 2;22(1):54
MYCT1 alters the glycogen shunt by regulating selective translation of RACK1-mediated enzymes.
Ding DX, Wang Y, Yan W, Fu WN
iScience 2022 Mar 18;25(3):103955
iScience 2022 Mar 18;25(3):103955
Structures of a deltacoronavirus spike protein bound to porcine and human receptors.
Ji W, Peng Q, Fang X, Li Z, Li Y, Xu C, Zhao S, Li J, Chen R, Mo G, Wei Z, Xu Y, Li B, Zhang S
Nature communications 2022 Mar 18;13(1):1467
Nature communications 2022 Mar 18;13(1):1467
Cancer stem cell regulated phenotypic plasticity protects metastasized cancer cells from ferroptosis.
Wu M, Zhang X, Zhang W, Chiou YS, Qian W, Liu X, Zhang M, Yan H, Li S, Li T, Han X, Qian P, Liu S, Pan Y, Lobie PE, Zhu T
Nature communications 2022 Mar 16;13(1):1371
Nature communications 2022 Mar 16;13(1):1371
Novel phosphanegold(I) thiolate complexes suppress de novo lipid synthesis in human lung cancer.
Luo M, Ma X, Jiang W, Zhang J, Liu W, Wei S, Liu H
European journal of medicinal chemistry 2022 Mar 15;232:114168
European journal of medicinal chemistry 2022 Mar 15;232:114168
Transition of autophagy and apoptosis in fibroblasts depends on dominant expression of HIF-1α or p53.
Li M, Su Y, Gao X, Yu J, Wang Z, Wang X
Journal of Zhejiang University. Science. B 2022 Mar 15;23(3):204-217
Journal of Zhejiang University. Science. B 2022 Mar 15;23(3):204-217
ALKBH3-dependent m(1)A demethylation of Aurora A mRNA inhibits ciliogenesis.
Kuang W, Jin H, Yang F, Chen X, Liu J, Li T, Chang Y, Liu M, Xu Z, Huo C, Yan X, Yang Y, Liu W, Shu Q, Xie S, Zhou T
Cell discovery 2022 Mar 11;8(1):25
Cell discovery 2022 Mar 11;8(1):25
Knockdown of long noncoding RNA MIAT attenuates cigarette smoke-induced airway remodeling by downregulating miR-29c-3p-HIF3A axis.
Gu W, Wang L, Deng G, Gu X, Tang Z, Li S, Jin W, Yang J, Guo X, Li Q
Toxicology letters 2022 Mar 1;357:11-19
Toxicology letters 2022 Mar 1;357:11-19
Zinc finger protein 91 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation.
Zhong Y, Zhang ZH, Wang JY, Xing Y, Ri MH, Jin HL, Zuo HX, Li MY, Ma J, Jin X
Toxicology letters 2022 Mar 1;356:75-88
Toxicology letters 2022 Mar 1;356:75-88
Systematic characterization of the metabolites of defatted walnut powder extract in vivo and screening of the mechanisms against NAFLD by UPLC-Q-Exactive Orbitrap MS combined with network pharmacology.
Ren SM, Zhang QZ, Jiang M, Chen ML, Xu XJ, Wang DM, Pan YN, Liu XQ
Journal of ethnopharmacology 2022 Mar 1;285:114870
Journal of ethnopharmacology 2022 Mar 1;285:114870
RKIP Induction Promotes Tumor Differentiation via SOX2 Degradation in NF2-Deficient Conditions.
Cho JH, Park S, Kim S, Kang SM, Woo TG, Yoon MH, Lee H, Jeong M, Park YH, Kim H, Han YT, Suh YG, Kim BH, Kwon Y, Yun H, Park BJ
Molecular cancer research : MCR 2022 Mar 1;20(3):412-424
Molecular cancer research : MCR 2022 Mar 1;20(3):412-424
Tumor Necrosis Factor-α-Induced Protein 8-Like 2 Fosters Tumor-Associated Microbiota to Promote the Development of Colorectal Cancer.
Lou Y, Song M, Han M, Zhong J, Tian X, Ren Y, Song Y, Duan L, Zhao P, Song X, Zhang W, Chen YH, Wang H
Cancer immunology research 2022 Mar 1;10(3):354-367
Cancer immunology research 2022 Mar 1;10(3):354-367
KLF2 mediates the suppressive effect of BDNF on diabetic intimal calcification by inhibiting HK1 induced endothelial-to-mesenchymal transition.
Wang FF, Zhang JL, Ji Y, Yan XJ, Sun L, Zhu Y, Jin H
Cellular signalling 2022 Jun;94:110324
Cellular signalling 2022 Jun;94:110324
Synchronous Disintegration of Ferroptosis Defense Axis via Engineered Exosome-Conjugated Magnetic Nanoparticles for Glioblastoma Therapy.
Li B, Chen X, Qiu W, Zhao R, Duan J, Zhang S, Pan Z, Zhao S, Guo Q, Qi Y, Wang W, Deng L, Ni S, Sang Y, Xue H, Liu H, Li G
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jun;9(17):e2105451
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jun;9(17):e2105451
Acute Myeloid Leukemia Cells Educate Mesenchymal Stromal Cells toward an Adipogenic Differentiation Propensity with Leukemia Promotion Capabilities.
Zhang L, Zhao Q, Cang H, Wang Z, Hu X, Pan R, Yang Y, Chen Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jun;9(16):2105811
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jun;9(16):2105811
Circ_0060731 mediated miR-21-5p-PDCD4/ESR1 pathway to induce apoptosis of placental trophoblasts in intrahepatic cholestasis of pregnancy.
Feng F, Lei L, Liao J, Huang X, Shao Y
Tissue & cell 2022 Jun;76:101771
Tissue & cell 2022 Jun;76:101771
Palbociclib regulates intracellular lipids in mammary tumor cells by secreting lipoprotein lipase.
Fujii T, Kamishikiryo J, Morita T
Pharmacological reports : PR 2022 Jun;74(3):503-512
Pharmacological reports : PR 2022 Jun;74(3):503-512
Targeting RPL23 restores chemosensitivity of cisplatin-resistant ovarian carcinoma by inhibiting EMT.
Liu Y, Lai S, He J, Wan J, Fu F, Jinlong Y
Cytotechnology 2022 Jun;74(3):421-432
Cytotechnology 2022 Jun;74(3):421-432
Differential Expression of CB(1) Cannabinoid Receptor and Cannabinoid Receptor Interacting Protein 1a in Labor.
Kozakiewicz ML, Zhang J, Leone-Kabler S, Yamaleyeva LM, McDonald AG, Brost BC, Howlett AC
Cannabis and cannabinoid research 2022 Jun;7(3):279-288
Cannabis and cannabinoid research 2022 Jun;7(3):279-288
Maternal Prkce expression in mature oocytes is critical for the first cleavage facilitating maternal-to-zygotic transition in mouse early embryos.
Zhang S, Gong X, Zhou Y, Ma Q, Cai Q, Yang G, Guo X, Chen Y, Xu M, Zhu Y, Zeng Y, Zeng F
Cell proliferation 2022 Jun;55(6):e13231
Cell proliferation 2022 Jun;55(6):e13231
Bicyclol alleviates high-fat diet-induced hepatic ER stress- and autophagy-associated non-alcoholic fatty liver disease/non-alcoholic steatohepatitis in mice.
Jia S, Jin L, Cheng X, Wu J, Yao X, Shao J, Zhang C, Cen D, Cheng B, Wang J, Chen L, Yao X
Drug development and industrial pharmacy 2022 Jun;48(6):247-254
Drug development and industrial pharmacy 2022 Jun;48(6):247-254
Tetrandrine Ameliorates Traumatic Brain Injury by Regulating Autophagy to Reduce Ferroptosis.
Liu H, He S, Wang J, Li C, Liao Y, Zou Q, Chen R
Neurochemical research 2022 Jun;47(6):1574-1587
Neurochemical research 2022 Jun;47(6):1574-1587
The function and mechanism of dopamine in the activation of CD4(+) T cell.
Shao Y, Dong Y, Wang W, Chen Z, Hao C, Yang Y, Zhang J
Immunopharmacology and immunotoxicology 2022 Jun;44(3):410-420
Immunopharmacology and immunotoxicology 2022 Jun;44(3):410-420
Osthole inhibits the migration and invasion of highly metastatic breast cancer cells by suppressing ITGα3/ITGβ5 signaling.
Chen YQ, Song HY, Zhou ZY, Ma J, Luo ZY, Zhou Y, Wang JY, Liu S, Han XH
Acta pharmacologica Sinica 2022 Jun;43(6):1544-1555
Acta pharmacologica Sinica 2022 Jun;43(6):1544-1555
LncRNA-6395 promotes myocardial ischemia-reperfusion injury in mice through increasing p53 pathway.
Zhan LF, Zhang Q, Zhao L, Dong X, Pei XY, Peng LL, Zhang XW, Meng B, Shang WD, Pan ZW, Xu CQ, Lu YJ, Zhang MY
Acta pharmacologica Sinica 2022 Jun;43(6):1383-1394
Acta pharmacologica Sinica 2022 Jun;43(6):1383-1394
Caffeine Citrate Protects Against Sepsis-Associated Encephalopathy and Inhibits the UCP2/NLRP3 Axis in Astrocytes.
Hu J, Cheng Y, Chen P, Huang Z, Yang L
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2022 Jun;42(6):267-278
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2022 Jun;42(6):267-278
Melatonin Alleviates Liver Fibrosis by Inhibiting Autophagy.
Jie L, Hong RT, Zhang YJ, Sha LL, Chen W, Ren XF
Current medical science 2022 Jun;42(3):498-504
Current medical science 2022 Jun;42(3):498-504
ADH1C Facilitates Cisplatin Resistance of Lung Adenocarcinoma Cells.
Jiang F, Shen Q, Zhang F, Fu J, Hu L, Wang J, Zhou H, Chen J, Wang Y
DNA and cell biology 2022 Jun;41(6):631-640
DNA and cell biology 2022 Jun;41(6):631-640
Protection of pancreatic β-cell by phosphocreatine through mitochondrial improvement via the regulation of dual AKT/IRS-1/GSK-3β and STAT3/Cyp-D signaling pathways.
Wang H, Ai J, Shopit A, Niu M, Ahmed N, Tesfaldet T, Tang Z, Li X, Jamalat Y, Chu P, Peng J, Ma X, Qaed E, Han G, Zhang W, Wang J, Tang Z
Cell biology and toxicology 2022 Jun;38(3):531-551
Cell biology and toxicology 2022 Jun;38(3):531-551
HDM induce airway epithelial cell ferroptosis and promote inflammation by activating ferritinophagy in asthma.
Zeng Z, Huang H, Zhang J, Liu Y, Zhong W, Chen W, Lu Y, Qiao Y, Zhao H, Meng X, Zou F, Cai S, Dong H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jun;36(6):e22359
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jun;36(6):e22359
Rutin-activated adipose tissue thermogenesis is correlated with increased intestinal short-chain fatty acid levels.
Cheng L, Shi L, He C, Wang C, Lv Y, Li H, An Y, Dai H, Duan Y, Zhang H, Huang Y, Fu W, Meng Y, Zhao B
Phytotherapy research : PTR 2022 Jun;36(6):2495-2510
Phytotherapy research : PTR 2022 Jun;36(6):2495-2510
MiR-153 downregulation alleviates PTSD-like behaviors and reduces cell apoptosis by upregulating the Sigma-1 receptor in the hippocampus of rats exposed to single-prolonged stress.
Chen YL, Tong L, Chen Y, Fu CH, Peng JB, Ji LL
Experimental neurology 2022 Jun;352:114034
Experimental neurology 2022 Jun;352:114034
Early environmental enrichment for autism spectrum disorder Fmr1 mice models has positive behavioral and molecular effects.
Chen YS, Zhang SM, Yue CX, Xiang P, Li JQ, Wei Z, Xu L, Zeng Y
Experimental neurology 2022 Jun;352:114033
Experimental neurology 2022 Jun;352:114033
The anti-angiogenesis mechanism of Geniposide on rheumatoid arthritis is related to the regulation of PTEN.
Bu Y, Wu H, Deng R, Wang Y
Inflammopharmacology 2022 Jun;30(3):1047-1062
Inflammopharmacology 2022 Jun;30(3):1047-1062
Alternative splicing of the human rhomboid family-1 gene RHBDF1 inhibits epidermal growth factor receptor activation.
Ji R, Shi Q, Cao Y, Zhang J, Zhao C, Zhao H, Sayyed Y, Fu L, Li LY
The Journal of biological chemistry 2022 Jun;298(6):102033
The Journal of biological chemistry 2022 Jun;298(6):102033
Mammalian PERIOD2 regulates H2A.Z incorporation in chromatin to orchestrate circadian negative feedback.
Tartour K, Andriani F, Folco EG, Letkova D, Schneider R, Saidi I, Sato T, Welz PS, Benitah SA, Allier C, Padmanabhan K
Nature structural & molecular biology 2022 Jun;29(6):549-562
Nature structural & molecular biology 2022 Jun;29(6):549-562
Lithium attenuates blood-brain barrier damage and brain edema following intracerebral hemorrhage via an endothelial Wnt/β-catenin signaling-dependent mechanism in mice.
Song D, Ji YB, Huang XW, Ma YZ, Fang C, Qiu LH, Tan XX, Chen YM, Wang SN, Chang J, Guo F
CNS neuroscience & therapeutics 2022 Jun;28(6):862-872
CNS neuroscience & therapeutics 2022 Jun;28(6):862-872
Tanshinone IIA inhibits cell growth by suppressing SIX1-induced aerobic glycolysis in non-small cell lung cancer cells.
Qi H, Chen Z, Qin Y, Wang X, Zhang Z, Li Y
Oncology letters 2022 Jun;23(6):184
Oncology letters 2022 Jun;23(6):184
Proteomic analysis reveals the heterogeneity of metabolic reprogramming in lacrimal gland tumors.
Yang J, Li Y, Gao W, Feng Y, He X, Ni H, Song X, Fan J
Experimental eye research 2022 Jun;219:109052
Experimental eye research 2022 Jun;219:109052
MicroRNA-221-5p Promotes Ricin Toxin-induced Inflammation via PI3K/Akt signaling pathway by targeting COL4a5.
Zhao N, Yu H, Xi Y, Dong M, Wang Y, Sun C, Zhang J, Xu N, Liu W
Toxicon : official journal of the International Society on Toxinology 2022 Jun;212:11-18
Toxicon : official journal of the International Society on Toxinology 2022 Jun;212:11-18
AMG487 inhibits PRRSV replication and ameliorates lung injury in pig lung xenografts by down-regulating the expression of ANXA2.
Liu J, Yao L, Huang S, Wang B, Li L, Li L, Gu W, Xiao S, Liu G
Antiviral research 2022 Jun;202:105314
Antiviral research 2022 Jun;202:105314
FAIM regulates autophagy through glutaminolysis in lung adenocarcinoma.
Han T, Wang P, Wang Y, Xun W, Lei J, Wang T, Lu Z, Gan M, Zhang W, Yu B, Wang JB
Autophagy 2022 Jun;18(6):1416-1432
Autophagy 2022 Jun;18(6):1416-1432
HGF Secreted by Mesenchymal Stromal Cells Promotes Primordial Follicle Activation by Increasing the Activity of the PI3K-AKT Signaling Pathway.
Mi X, Jiao W, Yang Y, Qin Y, Chen ZJ, Zhao S
Stem cell reviews and reports 2022 Jun;18(5):1834-1850
Stem cell reviews and reports 2022 Jun;18(5):1834-1850
Ephedra herb reduces adriamycin-induced testicular toxicity by upregulating the gonadotropin-releasing hormone signalling pathway.
Fu Y, Yuan P, Zheng Y, Gao L, Wei Y, Chen Y, Li P, Ruan Y, Zheng X, Feng W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:113061
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:113061
Naringin suppressed airway inflammation and ameliorated pulmonary endothelial hyperpermeability by upregulating Aquaporin1 in lipopolysaccharide/cigarette smoke-induced mice.
Zhang HH, Zhou XJ, Zhong YS, Ji LT, Yu WY, Fang J, Ying HZ, Li CY
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:113035
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:113035
Berberine reduces hepatic ceramide levels to improve insulin resistance in HFD-fed mice by inhibiting HIF-2α.
Xia QS, Wu F, Wu WB, Dong H, Huang ZY, Xu L, Lu FE, Gong J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:112955
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:112955
Abrogation of ARF6 in promoting erastin-induced ferroptosis and mitigating capecitabine resistance in gastric cancer cells.
Geng D, Wu H
Journal of gastrointestinal oncology 2022 Jun;13(3):958-967
Journal of gastrointestinal oncology 2022 Jun;13(3):958-967
DR1 Activation Inhibits the Proliferation of Vascular Smooth Muscle Cells through Increasing Endogenous H(2)S in Diabetes.
Xi Y, Wen X, Zhang Y, Jiao L, Bai S, Shi S, Chang G, Wu R, Sun F, Hao J, Li H
Aging and disease 2022 Jun;13(3):910-926
Aging and disease 2022 Jun;13(3):910-926
Effects of 2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione on autophagy and the PI3K/AKT/mTOR signaling pathway in human cholangiocarcinoma QBC939 cells.
He Y, Li Y, Liang T, Mo S, Liao Y, Chen Z, Zhao S, Ran Q, Han C, Hoa PTT
Journal of gastrointestinal oncology 2022 Jun;13(3):1423-1432
Journal of gastrointestinal oncology 2022 Jun;13(3):1423-1432
SORTING NEXIN2 proteins mediate stomatal movement and the response to drought stress by modulating trafficking and protein levels of the ABA exporter ABCG25.
Liang C, Li C, Wu J, Zhao M, Chen D, Liu C, Chu J, Zhang W, Hwang I, Wang M
The Plant journal : for cell and molecular biology 2022 Jun;110(6):1603-1618
The Plant journal : for cell and molecular biology 2022 Jun;110(6):1603-1618
Dietary curcumin supplementation ameliorates placental inflammation in rats with intra-uterine growth retardation by inhibiting the NF-κB signaling pathway.
Qi L, Jiang J, Yu G, Zhang X, Qi X, Zhang J, Zhang L, Wang T
The Journal of nutritional biochemistry 2022 Jun;104:108973
The Journal of nutritional biochemistry 2022 Jun;104:108973
Genome-scale CRISPR-Cas9 screen reveals novel regulators of B7-H3 in tumor cells.
Zhao S, Wang Y, Yang N, Mu M, Wu Z, Li H, Tang X, Zhong K, Zhang Z, Huang C, Cao T, Zheng M, Wang G, Nie C, Yang H, Guo G, Zhou L, Zheng X, Tong A
Journal for immunotherapy of cancer 2022 Jun;10(6)
Journal for immunotherapy of cancer 2022 Jun;10(6)
Small molecule targeting FOXM1 DNA binding domain exhibits anti-tumor activity in ovarian cancer.
Zhang Z, Xue ST, Gao Y, Li Y, Zhou Z, Wang J, Li Z, Liu Z
Cell death discovery 2022 Jun 9;8(1):280
Cell death discovery 2022 Jun 9;8(1):280
Novel Sphingosine Kinase 1 Inhibitor Suppresses Growth of Solid Tumor and Inhibits the Lung Metastasis of Triple-Negative Breast Cancer.
Zhang S, Chen X, Wu C, Xu H, Xie X, Feng M, Hu S, Bai H, Gao F, Tong L, Ding J, Liu H, Xie Z, Wang J
Journal of medicinal chemistry 2022 Jun 9;65(11):7697-7716
Journal of medicinal chemistry 2022 Jun 9;65(11):7697-7716
Recombinant ACE2 protein protects against acute lung injury induced by SARS-CoV-2 spike RBD protein.
Zhang L, Zhang Y, Qin X, Jiang X, Zhang J, Mao L, Jiang Z, Jiang Y, Liu G, Qiu J, Chen C, Qiu F, Zou Z
Critical care (London, England) 2022 Jun 9;26(1):171
Critical care (London, England) 2022 Jun 9;26(1):171
Zebrafish Xenograft Model for Studying Pancreatic Cancer-Instructed Innate Immune Microenvironment.
Wang X, Li W, Jiang H, Ma C, Huang M, Wei X, Wang W, Jing L
International journal of molecular sciences 2022 Jun 9;23(12)
International journal of molecular sciences 2022 Jun 9;23(12)
Novel Thermosensitive Hydrogel Promotes Spinal Cord Repair by Regulating Mitochondrial Function.
Li Y, Yang L, Hu F, Xu J, Ye J, Liu S, Wang L, Zhuo M, Ran B, Zhang H, Ye J, Xiao J
ACS applied materials & interfaces 2022 Jun 8;14(22):25155-25172
ACS applied materials & interfaces 2022 Jun 8;14(22):25155-25172
Structural basis of substrate recognition and translocation by human very long-chain fatty acid transporter ABCD1.
Chen ZP, Xu D, Wang L, Mao YX, Li Y, Cheng MT, Zhou CZ, Hou WT, Chen Y
Nature communications 2022 Jun 8;13(1):3299
Nature communications 2022 Jun 8;13(1):3299
The circadian clock protein Rev-erbα provides neuroprotection and attenuates neuroinflammation against Parkinson's disease via the microglial NLRP3 inflammasome.
Kou L, Chi X, Sun Y, Han C, Wan F, Hu J, Yin S, Wu J, Li Y, Zhou Q, Zou W, Xiong N, Huang J, Xia Y, Wang T
Journal of neuroinflammation 2022 Jun 6;19(1):133
Journal of neuroinflammation 2022 Jun 6;19(1):133
Anti-tumor activity of polysaccharides extracted from Pinus massoniana pollen in colorectal cancer- in vitro and in vivo studies.
Shang H, Niu X, Cui W, Sha Z, Wang C, Huang T, Guo P, Wang X, Gao P, Zhang S, Wei K, Zhu R
Food & function 2022 Jun 6;13(11):6350-6361
Food & function 2022 Jun 6;13(11):6350-6361
Overexpression of VPS16 correlates with tumor progression and chemoresistance in colorectal cancer.
Zhang B, Ma Y, Niu H, Liu Z
Biochemical and biophysical research communications 2022 Jun 4;607:81-88
Biochemical and biophysical research communications 2022 Jun 4;607:81-88
Carboxymethyl Chitosan Modified Oxymatrine Liposomes for the Alleviation of Emphysema in Mice via Pulmonary Administration.
Peng J, Cai Z, Wang Q, Zhou J, Xu J, Pan D, Chen T, Zhang G, Tao L, Chen Y, Shen X
Molecules (Basel, Switzerland) 2022 Jun 4;27(11)
Molecules (Basel, Switzerland) 2022 Jun 4;27(11)
C. elegans monitor energy status via the AMPK pathway to trigger innate immune responses against bacterial pathogens.
Ju S, Chen H, Wang S, Lin J, Ma Y, Aroian RV, Peng D, Sun M
Communications biology 2022 Jun 30;5(1):643
Communications biology 2022 Jun 30;5(1):643
Extracellular Vesicles-Encapsulated miR-153-3p Potentiate the Survival and Invasion of Lung Adenocarcinoma.
Cao H, Zhang P, Yu H, Xi J
Molecules and cells 2022 Jun 30;45(6):376-387
Molecules and cells 2022 Jun 30;45(6):376-387
Targeting the SREBP-1/Hsa-Mir-497/SCAP/FASN Oncometabolic Axis Inhibits the Cancer Stem-like and Chemoresistant Phenotype of Non-Small Cell Lung Carcinoma Cells.
Tiong TY, Weng PW, Wang CH, Setiawan SA, Yadav VK, Pikatan NW, Fong IH, Yeh CT, Hsu CH, Kuo KT
International journal of molecular sciences 2022 Jun 30;23(13)
International journal of molecular sciences 2022 Jun 30;23(13)
The mechanism of dioscin preventing lung cancer based on network pharmacology and experimental validation.
Xi P, Niu Y, Zhang Y, Li W, Gao F, Gu W, Kui F, Liu Z, Lu L, Du G
Journal of ethnopharmacology 2022 Jun 28;292:115138
Journal of ethnopharmacology 2022 Jun 28;292:115138
All-trans retinoic acid increases the pathogenicity of the H9N2 influenza virus in mice.
Niu X, Wang H, Zhao L, Lian P, Bai Y, Li J, Qiao J
Virology journal 2022 Jun 28;19(1):113
Virology journal 2022 Jun 28;19(1):113
Oncostatin M receptor regulates osteoblast differentiation via extracellular signal-regulated kinase/autophagy signaling.
Zhou J, Yang J, Dong Y, Shi Y, Zhu E, Yuan H, Li X, Wang B
Stem cell research & therapy 2022 Jun 28;13(1):278
Stem cell research & therapy 2022 Jun 28;13(1):278
Salubrinal-mediated activation of eIF2α signaling improves oxidative stress-induced BMSCs senescence and senile osteoporosis.
Li L, Hu G, Xie R, Yang J, Shi X, Jia Z, Qu X, Wang M, Wu Y
Biochemical and biophysical research communications 2022 Jun 25;610:70-76
Biochemical and biophysical research communications 2022 Jun 25;610:70-76
KDM6B promotes PARthanatos via suppression of O6-methylguanine DNA methyltransferase repair and sustained checkpoint response.
Yang M, Wang C, Zhou M, Bao L, Wang Y, Kumar A, Xing C, Luo W, Wang Y
Nucleic acids research 2022 Jun 24;50(11):6313-6331
Nucleic acids research 2022 Jun 24;50(11):6313-6331
Bisacodyl Limits Chikungunya Virus Replication In Vitro and Is Broadly Antiviral.
LoMascolo NJ, Cruz-Pulido YE, Mounce BC
Antimicrobial agents and chemotherapy 2022 Jun 21;66(6):e0029222
Antimicrobial agents and chemotherapy 2022 Jun 21;66(6):e0029222
Ferroptosis participates in neuron damage in experimental cerebral malaria and is partially induced by activated CD8(+) T cells.
Liang J, Shen Y, Wang Y, Huang Y, Wang J, Zhu Q, Tong G, Yu K, Cao W, Wang Q, Li Y, Zhao Y
Molecular brain 2022 Jun 20;15(1):57
Molecular brain 2022 Jun 20;15(1):57
Phloretin ameliorates diabetic nephropathy by inhibiting nephrin and podocin reduction through a non-hypoglycemic effect.
Liu J, Sun M, Xia Y, Cui X, Jiang J
Food & function 2022 Jun 20;13(12):6613-6622
Food & function 2022 Jun 20;13(12):6613-6622
Baicalin alleviates endometrial inflammatory injury through regulation of tight junction proteins.
Yang D, Yin R, Lei Q, Zhu J, Nan S, Ma N, Zhu H, Chen J, Han L, Ding M, Ding Y
Food & function 2022 Jun 20;13(12):6522-6533
Food & function 2022 Jun 20;13(12):6522-6533
Probiotic Bifidobacterium breve MCC1274 Mitigates Alzheimer's Disease-Related Pathologies in Wild-Type Mice.
Abdelhamid M, Zhou C, Jung CG, Michikawa M
Nutrients 2022 Jun 19;14(12)
Nutrients 2022 Jun 19;14(12)
Enhanced autophagy promotes radiosensitivity by mediating Sirt1 downregulation in RM-1 prostate cancer cells.
Wang KX, Yan C, Yang X, Zhu PY, Cui WW, Ye C, Hu K, Lan T, Huang LY, Wang W, Ma P, Qi SH, Gu B, Luo L
Biochemical and biophysical research communications 2022 Jun 18;609:84-92
Biochemical and biophysical research communications 2022 Jun 18;609:84-92
Inhibition of noncaspase proteases, calpain and proteasome, via ALLN and Bortezomib contributes to cell death through low degradation of pro-/anti-apoptotic proteins and apoptosis induction.
Hamidi R, Ataei F, Hosseinkhani S
Medical oncology (Northwood, London, England) 2022 Jun 18;39(9):125
Medical oncology (Northwood, London, England) 2022 Jun 18;39(9):125
Inhibition of AKT induces p53/SIRT6/PARP1-dependent parthanatos to suppress tumor growth.
Zhang Y, Zhang C, Li J, Jiang M, Guo S, Yang G, Zhang L, Wang F, Yi S, Wang J, Fu Y, Zhang Y
Cell communication and signaling : CCS 2022 Jun 17;20(1):93
Cell communication and signaling : CCS 2022 Jun 17;20(1):93
Phosphorylation of guanosine monophosphate reductase triggers a GTP-dependent switch from pro- to anti-oncogenic function of EPHA4.
Wolff DW, Deng Z, Bianchi-Smiraglia A, Foley CE, Han Z, Wang X, Shen S, Rosenberg MM, Moparthy S, Yun DH, Chen J, Baker BK, Roll MV, Magiera AJ, Li J, Hurley E, Feltri ML, Cox AO, Lee J, Furdui CM, Liu L, Bshara W, LaConte LEW, Kandel ES, Pasquale EB, Qu J, Hedstrom L, Nikiforov MA
Cell chemical biology 2022 Jun 16;29(6):970-984.e6
Cell chemical biology 2022 Jun 16;29(6):970-984.e6
Host Zinc-finger CCHC-type containing protein 3 inhibits pseudorabies virus proliferation by regulating type I interferon signaling.
Chen X, Shan T, Sun D, Zhai H, Dong S, Kong N, Zheng H, Tong W, Tong G
Gene 2022 Jun 15;827:146480
Gene 2022 Jun 15;827:146480
Integrated analysis of tRNA-derived small RNAs in proliferative human aortic smooth muscle cells.
Zhao JZ, Li QY, Lin JJ, Yang LY, Du MY, Wang Y, Liu KX, Jiang ZA, Li HH, Wang SF, Sun B, Mu SQ, Li B, Liu K, Gong M, Sun SG
Cellular & molecular biology letters 2022 Jun 15;27(1):47
Cellular & molecular biology letters 2022 Jun 15;27(1):47
JNK and Jag1/Notch2 co-regulate CXCL16 to facilitate cypermethrin-induced kidney damage.
Liu C, Wu M, Qu J, Huang X, Zeng Q, Ha M
Ecotoxicology and environmental safety 2022 Jun 15;238:113582
Ecotoxicology and environmental safety 2022 Jun 15;238:113582
Integrated metabolism and epigenetic modifications in the macrophages of mice in responses to cold stress.
Lu J, Fu S, Dai J, Hu J, Li S, Ji H, Wang Z, Yu J, Bao J, Xu B, Guo J, Yang H
Journal of Zhejiang University. Science. B 2022 Jun 15;23(6):461-480
Journal of Zhejiang University. Science. B 2022 Jun 15;23(6):461-480
SARS-CoV-2 productively infects human brain microvascular endothelial cells.
Yang RC, Huang K, Zhang HP, Li L, Zhang YF, Tan C, Chen HC, Jin ML, Wang XR
Journal of neuroinflammation 2022 Jun 15;19(1):149
Journal of neuroinflammation 2022 Jun 15;19(1):149
Inhibition of the lncRNA MIAT prevents podocyte injury and mitotic catastrophe in diabetic nephropathy.
Wang Z, Chang Y, Liu Y, Liu B, Zhen J, Li X, Lin J, Yu Q, Lv Z, Wang R
Molecular therapy. Nucleic acids 2022 Jun 14;28:136-153
Molecular therapy. Nucleic acids 2022 Jun 14;28:136-153
Protective Effects of Liquiritigenin against Cisplatin-Induced Nephrotoxicity via NRF2/SIRT3-Mediated Improvement of Mitochondrial Function.
Zhou M, Dai Y, Ma Y, Yan Y, Hua M, Gao Q, Geng X, Zhou Q
Molecules (Basel, Switzerland) 2022 Jun 14;27(12)
Molecules (Basel, Switzerland) 2022 Jun 14;27(12)
Resveratrol Induces Autophagy and Apoptosis in Non-Small-Cell Lung Cancer Cells by Activating the NGFR-AMPK-mTOR Pathway.
Li J, Fan Y, Zhang Y, Liu Y, Yu Y, Ma M
Nutrients 2022 Jun 10;14(12)
Nutrients 2022 Jun 10;14(12)
NCAPH is a prognostic biomarker and associated with immune infiltrates in lung adenocarcinoma.
Li C, Meng J, Zhang T
Scientific reports 2022 Jun 10;12(1):9578
Scientific reports 2022 Jun 10;12(1):9578
The role of ER stress and ATP/AMPK in oxidative stress meditated hepatotoxicity induced by citrinin.
Wu J, Yang C, Yang M, Liang Z, Wu Y, Kong X, Fan H, Wang S, Ning C, Xiao W, Jin Y, Yi J, Yuan Z
Ecotoxicology and environmental safety 2022 Jun 1;237:113531
Ecotoxicology and environmental safety 2022 Jun 1;237:113531
High-frequency repetitive transcranial magnetic stimulation mitigates depression-like behaviors in CUMS-induced rats via FGF2/FGFR1/p-ERK signaling pathway.
Yan J, Zhang F, Niu L, Wang X, Lu X, Ma C, Zhang C, Song J, Zhang Z
Brain research bulletin 2022 Jun 1;183:94-103
Brain research bulletin 2022 Jun 1;183:94-103
Large Yellow Tea Extract Ameliorates Metabolic Syndrome by Suppressing Lipogenesis through SIRT6/SREBP1 Pathway and Modulating Microbiota in Leptin Receptor Knockout Rats.
Wu G, Sun X, Cheng H, Xu S, Li D, Xie Z
Foods (Basel, Switzerland) 2022 Jun 1;11(11)
Foods (Basel, Switzerland) 2022 Jun 1;11(11)
Antioxidant potential of Pediococcus pentosaceus strains from the sow milk bacterial collection in weaned piglets.
Wang L, Liu Q, Chen Y, Zheng X, Wang C, Qi Y, Dong Y, Xiao Y, Chen C, Chen T, Huang Q, Zhai Z, Long C, Yang H, Li J, Wang L, Zhang G, Liao P, Liu YX, Huang P, Huang J, Wang Q, Chu H, Yin J, Yin Y
Microbiome 2022 Jun 1;10(1):83
Microbiome 2022 Jun 1;10(1):83
Hexokinase 2-mediated glycolysis promotes receptor activator of NF-κB ligand expression in Porphyromonas gingivalis lipopolysaccharide-treated osteoblasts.
Yu Y, Jiang L, Li J, Lei L, Li H
Journal of periodontology 2022 Jul;93(7):1036-1047
Journal of periodontology 2022 Jul;93(7):1036-1047
miR-520d-3p/MIG-7 axis regulates vasculogenic mimicry formation and metastasis in osteosarcoma.
Yao N, Zhou J, Song J, Jiang Y, Zhang J
Neoplasma 2022 Jul;69(4):764-775
Neoplasma 2022 Jul;69(4):764-775
Sema3A accelerates bone formation during distraction osteogenesis in mice.
Zhang N, Hua Y, Li Y, Pan J
Connective tissue research 2022 Jul;63(4):382-392
Connective tissue research 2022 Jul;63(4):382-392
Inhibition of nuclear deacetylase Sirtuin-1 induces mitochondrial acetylation and calcium overload leading to cell death.
Sun Y, Yang YM, Hu YY, Ouyang L, Sun ZH, Yin XF, Li N, He QY, Wang Y
Redox biology 2022 Jul;53:102334
Redox biology 2022 Jul;53:102334
Dopamine 1 receptors inhibit apoptosis via activating CSE/H(2) S pathway in high glucose-induced vascular endothelial cells.
Li H, Wu R, Xi Y, Li H, Chang G, Sun F, Wei C, Jiao L, Wen X, Zhang G, Zaid A, Hao J
Cell biology international 2022 Jul;46(7):1098-1108
Cell biology international 2022 Jul;46(7):1098-1108
In utero hypoxia attenuated acetylcholine-mediated vasodilatation via CHRM3/p-NOS3 in fetal sheep MCA: role of ROS/ERK1/2.
He Y, Su H, Li N, Zhang Y, Zhang P, Zhang Y, Ye Y, Zhang Y, Tang J, Xu Z
Hypertension research : official journal of the Japanese Society of Hypertension 2022 Jul;45(7):1168-1182
Hypertension research : official journal of the Japanese Society of Hypertension 2022 Jul;45(7):1168-1182
Curcumin attenuates isoniazid-induced hepatotoxicity by upregulating the SIRT1/PGC-1α/NRF1 pathway.
Li Y, Luo WW, Cheng X, Xiang HR, He B, Zhang QZ, Peng WX
Journal of applied toxicology : JAT 2022 Jul;42(7):1192-1204
Journal of applied toxicology : JAT 2022 Jul;42(7):1192-1204
PCDHB14 promotes ferroptosis and is a novel tumor suppressor in hepatocellular carcinoma.
Liu Y, Ouyang L, Mao C, Chen Y, Li T, Liu N, Wang Z, Lai W, Zhou Y, Cao Y, Liu S, Liang Y, Wang M, Liu S, Chen L, Shi Y, Xiao D, Tao Y
Oncogene 2022 Jul;41(27):3570-3583
Oncogene 2022 Jul;41(27):3570-3583
Podophyllotoxin-combined 5-aminolevulinic acid photodynamic therapy significantly promotes HR-HPV-infected cell death.
Wang J, Wang Q, Chen P, Li Q, Li Z, Xu M, Zeng K, Li C
Photodermatology, photoimmunology & photomedicine 2022 Jul;38(4):343-353
Photodermatology, photoimmunology & photomedicine 2022 Jul;38(4):343-353
Entacapone alleviates acute kidney injury by inhibiting ferroptosis.
Yang J, Sun X, Huang N, Li P, He J, Jiang L, Zhang X, Han S, Xin H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jul;36(7):e22399
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jul;36(7):e22399
Periostin promotes nucleus pulposus cells apoptosis by activating the Wnt/β-catenin signaling pathway.
Zhu D, Wang Z, Zhang G, Ma C, Qiu X, Wang Y, Liu M, Guo X, Chen H, Deng Q, Kang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jul;36(7):e22369
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jul;36(7):e22369
Trilobatin promotes angiogenesis after cerebral ischemia-reperfusion injury via SIRT7/VEGFA signaling pathway in rats.
Huang F, Luo L, Wu Y, Xia D, Xu F, Gao J, Shi J, Gong Q
Phytotherapy research : PTR 2022 Jul;36(7):2940-2951
Phytotherapy research : PTR 2022 Jul;36(7):2940-2951
A dual crosslinked hydrogel-mediated integrated peptides and BMSC therapy for myocardial regeneration.
Zheng Z, Guo Z, Zhong F, Wang B, Liu L, Ma W, Yu CY, Wei H
Journal of controlled release : official journal of the Controlled Release Society 2022 Jul;347:127-142
Journal of controlled release : official journal of the Controlled Release Society 2022 Jul;347:127-142
Prognostic and functional role of hyaluronan-binding protein 1 in pancreatic ductal adenocarcinoma.
Adachi Y, Sato N, Oba T, Amaike T, Kudo Y, Kohi S, Nakayama T, Hirata K
Oncology letters 2022 Jul;24(1):222
Oncology letters 2022 Jul;24(1):222
Inhibition of Drp1 ameliorates diabetic retinopathy by regulating mitochondrial homeostasis.
Zhang MY, Zhu L, Bao X, Xie TH, Cai J, Zou J, Wang W, Gu S, Li Y, Li HY, Yao Y, Wei TT
Experimental eye research 2022 Jul;220:109095
Experimental eye research 2022 Jul;220:109095
Inhibition of Cpt1a alleviates oxidative stress-induced chondrocyte senescence via regulating mitochondrial dysfunction and activating mitophagy.
Jiang N, Xing B, Peng R, Shang J, Wu B, Xiao P, Lin S, Xu X, Lu H
Mechanisms of ageing and development 2022 Jul;205:111688
Mechanisms of ageing and development 2022 Jul;205:111688
Elevation of N-acetyltransferase 10 in hippocampal neurons mediates depression- and anxiety-like behaviors.
Guo XF, Wang XH, Fu YL, Meng Q, Huang BY, Yang R, Guo Y, Du YR, Wang X, Gao Y, Song L, Gong M, Wang S, Li YD, Shi HS, Shi Y
Brain research bulletin 2022 Jul;185:91-98
Brain research bulletin 2022 Jul;185:91-98
Newcastle disease virus degrades SIRT3 via PINK1-PRKN-dependent mitophagy to reprogram energy metabolism in infected cells.
Gong Y, Tang N, Liu P, Sun Y, Lu S, Liu W, Tan L, Song C, Qiu X, Liao Y, Yu S, Liu X, Lin SH, Ding C
Autophagy 2022 Jul;18(7):1503-1521
Autophagy 2022 Jul;18(7):1503-1521
Amentoflavone attenuates Listeria monocytogenes pathogenicity through an LLO-dependent mechanism.
Tingting W, Tianqi F, Xinyu W, Can Z, Xue S, Xuming D, Jianfeng W
British journal of pharmacology 2022 Jul;179(14):3839-3858
British journal of pharmacology 2022 Jul;179(14):3839-3858
The neuroprotective effects of GPR55 against hippocampal neuroinflammation and impaired adult neurogenesis in CSDS mice.
Shen SY, Yu R, Li W, Liang LF, Han QQ, Huang HJ, Li B, Xu SF, Wu GC, Zhang YQ, Yu J
Neurobiology of disease 2022 Jul;169:105743
Neurobiology of disease 2022 Jul;169:105743
Hippocampal AMPA receptors mediate the impairment of spatial learning and memory in prenatally stressed offspring rats.
Yao D, Mu Y, Lu Y, Li L, Shao S, Zhou J, Li J, Chen S, Zhang D, Zhang Y, Zhu Z, Li H
Journal of psychiatric research 2022 Jul;151:17-24
Journal of psychiatric research 2022 Jul;151:17-24
Dasatinib suppresses atherosclerotic lesions by suppressing cholesterol uptake in a mouse model of hypercholesterolemia.
Takaba M, Iwaki T, Arakawa T, Ono T, Maekawa Y, Umemura K
Journal of pharmacological sciences 2022 Jul;149(3):158-165
Journal of pharmacological sciences 2022 Jul;149(3):158-165
Discovery of cinnamamide-barbiturate hybrids as a novel class of Nrf2 activator against myocardial ischemia/reperfusion injury.
Wei B, Zhang J, Li NN, Yang LH, Xu XL, Shi YY, Liu SH, Chen YJ
Bioorganic chemistry 2022 Jul;124:105828
Bioorganic chemistry 2022 Jul;124:105828
Targeting chemoresistance in Xp11.2 translocation renal cell carcinoma using a novel polyamide-chlorambucil conjugate.
Funasaki S, Mehanna S, Ma W, Nishizawa H, Kamikubo Y, Sugiyama H, Ikeda S, Motoshima T, Hasumi H, Linehan WM, Schmidt LS, Ricketts C, Suda T, Oike Y, Kamba T, Baba M
Cancer science 2022 Jul;113(7):2352-2367
Cancer science 2022 Jul;113(7):2352-2367
IL-17A drives cognitive aging probably via inducing neuroinflammation and theta oscillation disruption in the hippocampus.
Li Y, Mao M, Zhu L, Sun Q, Tong J, Zhou Z
International immunopharmacology 2022 Jul;108:108898
International immunopharmacology 2022 Jul;108:108898
Thiamine pretreatment improves endotoxemia-related liver injury and cholestatic complications by regulating galactose metabolism and inhibiting macrophage activation.
Li T, Bai J, Du Y, Tan P, Zheng T, Chen Y, Cheng Y, Cai T, Huang M, Fu W, Wen J
International immunopharmacology 2022 Jul;108:108892
International immunopharmacology 2022 Jul;108:108892
Pemafibrate attenuates pulmonary fibrosis by inhibiting myofibroblast differentiation.
Liu Y, Chen S, Yu L, Deng Y, Li D, Yu X, Chen D, Lu Y, Liu S, Chen R
International immunopharmacology 2022 Jul;108:108728
International immunopharmacology 2022 Jul;108:108728
Perilipin 5 protects against oxygen-glucose deprivation/reoxygenation-elicited neuronal damage by inhibiting oxidative stress and inflammatory injury via the Akt-GSK-3β-Nrf2 pathway.
Huo K, Ma KG, Guo QY, Duan P, Xu J
International immunopharmacology 2022 Jul;108:108718
International immunopharmacology 2022 Jul;108:108718
Cellular protein HSC70 promotes fowl adenovirus serotype 4 replication in LMH cells via interacting with viral 100K protein.
Gao S, Chen H, Zhang X, Zhao J, Wang Z
Poultry science 2022 Jul;101(7):101941
Poultry science 2022 Jul;101(7):101941
Effect of starvation and refeeding on reactive oxygen species, autophagy and oxidative stress in Chinese perch (Siniperca chuatsi) muscle growth.
Wu P, Chen L, Cheng J, Pan Y, Zhu X, Chu W, Zhang J
Journal of fish biology 2022 Jul;101(1):168-178
Journal of fish biology 2022 Jul;101(1):168-178
Gallic acid induces T-helper-1-like T(reg) cells and strengthens immune checkpoint blockade efficacy.
Deng B, Yang B, Chen J, Wang S, Zhang W, Guo Y, Han Y, Li H, Dang Y, Yuan Y, Dai X, Zang Y, Li Y, Li B
Journal for immunotherapy of cancer 2022 Jul;10(7)
Journal for immunotherapy of cancer 2022 Jul;10(7)
Induction of endothelial barrier dysfunction by serum factors in rats subjected to traumatic brain injury and hemorrhagic shock.
Ke Y, Proctor JL, Zhang C, Medina J, Miller CHT, Kim J, Grissom TE, Birukova AA, Fiskum GM, Birukov KG
Physiological reports 2022 Jul;10(13):e15350
Physiological reports 2022 Jul;10(13):e15350
LncRNA HOTTIP PROMOTES OVARIAN CANCER CELL INVASION AND METASTASIS BY STABILIZING HIF-1α IN THE ANOXIC CELLULAR MICROENVIRONMENT.
Zhang S, Ma Q, Wu X, Chen P
Acta endocrinologica (Bucharest, Romania : 2005) 2022 Jul-Sep;18(3):263-270
Acta endocrinologica (Bucharest, Romania : 2005) 2022 Jul-Sep;18(3):263-270
Gankyrin modulated non-small cell lung cancer progression via glycolysis metabolism in a YAP1-dependent manner.
Yu T, Liu Y, Xue J, Sun X, Zhu D, Ma L, Guo Y, Jin T, Cao H, Chen Y, Zhu T, Li X, Liang H, Du Z, Shan H
Cell death discovery 2022 Jul 9;8(1):312
Cell death discovery 2022 Jul 9;8(1):312
Hypoxia-Induced Scleral HIF-2α Upregulation Contributes to Rises in MMP-2 Expression and Myopia Development in Mice.
Wu W, Su Y, Hu C, Tao H, Jiang Y, Zhu G, Zhu J, Zhai Y, Qu J, Zhou X, Zhao F
Investigative ophthalmology & visual science 2022 Jul 8;63(8):2
Investigative ophthalmology & visual science 2022 Jul 8;63(8):2
PFKM inhibits doxorubicin-induced cardiotoxicity by enhancing oxidative phosphorylation and glycolysis.
Zhou M, Sun X, Wang C, Wang F, Fang C, Hu Z
Scientific reports 2022 Jul 8;12(1):11684
Scientific reports 2022 Jul 8;12(1):11684
Duck Tembusu virus infection induces mitochondrial-mediated and death receptor-mediated apoptosis in duck embryo fibroblasts.
Pan Y, Cai W, Cheng A, Wang M, Chen S, Huang J, Yang Q, Wu Y, Sun D, Mao S, Zhu D, Liu M, Zhao X, Zhang S, Gao Q, Ou X, Tian B, Yin Z, Jia R
Veterinary research 2022 Jul 7;53(1):53
Veterinary research 2022 Jul 7;53(1):53
Transcriptional landscape of human neuroblastoma cells in response to SARS-CoV-2.
Yang RC, Huang K, Zhang HP, Li L, Tan C, Chen HC, Jin ML, Wang XR
BMC neuroscience 2022 Jul 6;23(1):43
BMC neuroscience 2022 Jul 6;23(1):43
Targeting BCAT1 Combined with α-Ketoglutarate Triggers Metabolic Synthetic Lethality in Glioblastoma.
Zhang B, Peng H, Zhou M, Bao L, Wang C, Cai F, Zhang H, Wang JE, Niu Y, Chen Y, Wang Y, Hatanpaa KJ, Copland JA, DeBerardinis RJ, Wang Y, Luo W
Cancer research 2022 Jul 5;82(13):2388-2402
Cancer research 2022 Jul 5;82(13):2388-2402
Human chorion-derived mesenchymal stem cells suppress JAK2/STAT3 signaling and induce apoptosis of cholangiocarcinoma cell lines.
Jantalika T, Manochantr S, Kheolamai P, Tantikanlayaporn D, Saijuntha W, Pinlaor S, Chairoungdua A, Paraoan L, Tantrawatpan C
Scientific reports 2022 Jul 5;12(1):11341
Scientific reports 2022 Jul 5;12(1):11341
20(S)-Protopanaxadiol decreases atherosclerosis in ApoE KO mice by increasing the levels of LDLR and inhibiting its binding with PCSK9.
Huang YW, Zhang M, Wang LT, Nie Y, Yang JB, Meng WL, Wang XJ, Sheng J
Food & function 2022 Jul 4;13(13):7020-7028
Food & function 2022 Jul 4;13(13):7020-7028
Akkermansia muciniphila Colonization Alleviating High Fructose and Restraint Stress-Induced Jejunal Mucosal Barrier Disruption.
Yu J, Liu T, Gao Z, Liu R, Wang Z, Chen Y, Cao J, Dong Y
Nutrients 2022 Jul 30;14(15)
Nutrients 2022 Jul 30;14(15)
Cholesterol sulfate alleviates ulcerative colitis by promoting cholesterol biosynthesis in colonic epithelial cells.
Xu D, Ma R, Ju Y, Song X, Niu B, Hong W, Wang R, Yang Q, Zhao Z, Zhang Y, Zheng Y, Bai Q, Lv M, Sun N, Li X
Nature communications 2022 Jul 30;13(1):4428
Nature communications 2022 Jul 30;13(1):4428
LncRNA ANRIL mediates endothelial dysfunction through BDNF downregulation in chronic kidney disease.
Su H, Liu B, Chen H, Zhang T, Huang T, Liu Y, Wang C, Ma Q, Wang Q, Lv Z, Wang R
Cell death & disease 2022 Jul 29;13(7):661
Cell death & disease 2022 Jul 29;13(7):661
Pseudoislet Aggregation of Pancreatic β-Cells Improves Glucose Stimulated Insulin Secretion by Altering Glucose Metabolism and Increasing ATP Production.
Cornell D, Miwa S, Georgiou M, Anderson SJ, Honkanen-Scott M, Shaw JAM, Arden C
Cells 2022 Jul 29;11(15)
Cells 2022 Jul 29;11(15)
Dabie bandavirus Nonstructural Protein Interacts with Actin to Induce F-Actin Rearrangement and Inhibit Viral Adsorption and Entry.
Liu H, Liu S, Liu Z, Gao X, Xu L, Huang M, Su Y, Wang Z, Wang T
Journal of virology 2022 Jul 27;96(14):e0078822
Journal of virology 2022 Jul 27;96(14):e0078822
Effects of Artemisinin on Escherichia coli-Induced Mastitis in Bovine Mammary Epithelial Cells and Mice.
Li Z, Hu J, Wang X, Du Y, Yin J, Gao J, Han B, Cui S, Liu Y, Liu J
Veterinary sciences 2022 Jul 26;9(8)
Veterinary sciences 2022 Jul 26;9(8)
HDAC2- and EZH2-Mediated Histone Modifications Induce PDK1 Expression through miR-148a Downregulation in Breast Cancer Progression and Adriamycin Resistance.
Xie Y, Shi Z, Qian Y, Jiang C, Liu W, Liu B, Jiang B
Cancers 2022 Jul 23;14(15)
Cancers 2022 Jul 23;14(15)
Enhancement of Osteoblast Function through Extracellular Vesicles Derived from Adipose-Derived Stem Cells.
Ho ML, Hsu CJ, Wu CW, Chang LH, Chen JW, Chen CH, Huang KC, Chang JK, Wu SC, Shao PL
Biomedicines 2022 Jul 21;10(7)
Biomedicines 2022 Jul 21;10(7)
Prefrontal GABA(A)(δ)R Promotes Fear Extinction through Enabling the Plastic Regulation of Neuronal Intrinsic Excitability.
Pan HQ, Liu XX, He Y, Zhou J, Liao CZ, You WJ, Jiang SY, Qin X, Chen WB, Fei EK, Zhang WH, Pan BX
The Journal of neuroscience : the official journal of the Society for Neuroscience 2022 Jul 20;42(29):5755-5770
The Journal of neuroscience : the official journal of the Society for Neuroscience 2022 Jul 20;42(29):5755-5770
GRP75-driven, cell-cycle-dependent macropinocytosis of Tat/pDNA-Ca(2+) nanoparticles underlies distinct gene therapy effect in ovarian cancer.
Su L, Sun Z, Qi F, Su H, Qian L, Li J, Zuo L, Huang J, Yu Z, Li J, Chen Z, Zhang S
Journal of nanobiotechnology 2022 Jul 20;20(1):340
Journal of nanobiotechnology 2022 Jul 20;20(1):340
Thiostrepton induces ferroptosis in pancreatic cancer cells through STAT3/GPX4 signalling.
Zhang W, Gong M, Zhang W, Mo J, Zhang S, Zhu Z, Wang X, Zhang B, Qian W, Wu Z, Ma Q, Wang Z
Cell death & disease 2022 Jul 20;13(7):630
Cell death & disease 2022 Jul 20;13(7):630
The E3 ubiquitin ligase MG53 inhibits hepatocellular carcinoma by targeting RAC1 signaling.
Ma X, Ma X, Zhu L, Zhao Y, Chen M, Li T, Lin Y, Ma D, Sun C, Han L
Oncogenesis 2022 Jul 20;11(1):40
Oncogenesis 2022 Jul 20;11(1):40
β-Caryophyllene suppresses ferroptosis induced by cerebral ischemia reperfusion via activation of the NRF2/HO-1 signaling pathway in MCAO/R rats.
Hu Q, Zuo T, Deng L, Chen S, Yu W, Liu S, Liu J, Wang X, Fan X, Dong Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul 20;102:154112
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul 20;102:154112
Bisdemethoxycurcumin Attenuated Renal Injury via Activation of Keap1/Nrf2 Pathway in High-Fat Diet-Fed Mice.
Ding X, Chen Y, Zhou L, Wu R, Jian T, Lyu H, Liu Y, Chen J
International journal of molecular sciences 2022 Jul 2;23(13)
International journal of molecular sciences 2022 Jul 2;23(13)
Pseudorabies Virus Tegument Protein UL13 Suppresses RLR-Mediated Antiviral Innate Immunity through Regulating Receptor Transcription.
Zhao N, Wang F, Kong Z, Shang Y
Viruses 2022 Jul 2;14(7)
Viruses 2022 Jul 2;14(7)
N-glycosylation of GDF15 abolishes its inhibitory effect on EGFR in AR inhibitor-resistant prostate cancer cells.
Wang R, Wen P, Yang G, Feng Y, Mi Y, Wang X, Zhu S, Chen YQ
Cell death & disease 2022 Jul 19;13(7):626
Cell death & disease 2022 Jul 19;13(7):626
Viral evasion of PKR restriction by reprogramming cellular stress granules.
Gao P, Liu Y, Wang H, Chai Y, Weng W, Zhang Y, Zhou L, Ge X, Guo X, Han J, Yang H
Proceedings of the National Academy of Sciences of the United States of America 2022 Jul 19;119(29):e2201169119
Proceedings of the National Academy of Sciences of the United States of America 2022 Jul 19;119(29):e2201169119
Proteomic Mapping and Targeting of Mitotic Pericentriolar Material in Tumors Bearing Centrosome Amplification.
Xie B, Pu Y, Yang F, Chen W, Yue W, Ma J, Zhang N, Jiang Y, Wu J, Lin Y, Liang X, Wang C, Zou P, Li M
Cancer research 2022 Jul 18;82(14):2576-2592
Cancer research 2022 Jul 18;82(14):2576-2592
Iron deficiency exacerbates aortic medial degeneration by inducing excessive mitochondrial fission.
Zhong X, Wu Q, Wang Z, Zhang M, Zheng S, Shi F, Chen Y, Che Y, Yuan S, Xing K
Food & function 2022 Jul 18;13(14):7666-7683
Food & function 2022 Jul 18;13(14):7666-7683
Nicotinamide mononucleotide supplementation protects the intestinal function in aging mice and D-galactose induced senescent cells.
Ru M, Wang W, Zhai Z, Wang R, Li Y, Liang J, Kothari D, Niu K, Wu X
Food & function 2022 Jul 18;13(14):7507-7519
Food & function 2022 Jul 18;13(14):7507-7519
Effect of Qingyangshen glycosides on social defeat mice model.
Liu D, Wang J, Chang L, Zhu Q, Jiang N, Azhar M, Zeng G
Journal of ethnopharmacology 2022 Jul 15;293:115253
Journal of ethnopharmacology 2022 Jul 15;293:115253
Sulfate oligosaccharide of Gracilaria lemaneiformis modulates type 1 immunity by restraining T cell activation.
Liu Q, Zhou Y, Ma L, Gu F, Liao K, Liu Y, Zhang Y, Liu H, Hong Y, Cao M, Liu WH, Liu C, Liu G
Carbohydrate polymers 2022 Jul 15;288:119377
Carbohydrate polymers 2022 Jul 15;288:119377
The role of ciliopathy-associated type 3 adenylyl cyclase in infanticidal behavior in virgin adult male mice.
Wu X, Yang D, Zhou Y, Li S, Wang Z
iScience 2022 Jul 15;25(7):104534
iScience 2022 Jul 15;25(7):104534
N6-methyladenosine RNA demethylase ALKBH5 is testis-specifically downregulated in hybrid male sterile dzo and is a target gene of bta-miR-200a.
Chen H, Zhang J, Yan Y, Zhu C, Wang L, Fu S, Zuo F, Zhang GW
Theriogenology 2022 Jul 15;187:51-57
Theriogenology 2022 Jul 15;187:51-57
Monitoring Protein Import into the Endoplasmic Reticulum in Living Cells with Proximity Labeling.
Lyu Z, Sycks MM, Espinoza MF, Nguyen KK, Montoya MR, Galapate CM, Mei L, Genereux JC
ACS chemical biology 2022 Jul 15;17(7):1963-1977
ACS chemical biology 2022 Jul 15;17(7):1963-1977
KIFC3 promotes proliferation, migration and invasion of esophageal squamous cell carcinoma cells by activating EMT and β-catenin signaling.
Hao WW, Xu F
World journal of gastrointestinal oncology 2022 Jul 15;14(7):1239-1251
World journal of gastrointestinal oncology 2022 Jul 15;14(7):1239-1251
CCL20/CCR6 axis mediates macrophages to promote proliferation and migration of ESCs by blocking autophagic flux in endometriosis.
Tan J, Xu T, Gou Y, Wang H, Liang Z, Cao Y, Wang H, Yu Y, Jiao N, Zhang Z
Stem cell research & therapy 2022 Jul 15;13(1):294
Stem cell research & therapy 2022 Jul 15;13(1):294
Structure-Based Discovery of a Series of NSD2-PWWP1 Inhibitors.
Li N, Yang H, Liu K, Zhou L, Huang Y, Cao D, Li Y, Sun Y, Yu A, Du Z, Yu F, Zhang Y, Wang B, Geng M, Li J, Xiong B, Xu S, Huang X, Liu T
Journal of medicinal chemistry 2022 Jul 14;65(13):9459-9477
Journal of medicinal chemistry 2022 Jul 14;65(13):9459-9477
Chronic stress-induced depression requires the recruitment of peripheral Th17 cells into the brain.
Peng Z, Peng S, Lin K, Zhao B, Wei L, Tuo Q, Liao D, Yuan T, Shi Z
Journal of neuroinflammation 2022 Jul 14;19(1):186
Journal of neuroinflammation 2022 Jul 14;19(1):186
ZEB2/TWIST1/PRMT5/NuRD Multicomplex Contributes to the Epigenetic Regulation of EMT and Metastasis in Colorectal Carcinoma.
Zheng Y, Dai M, Dong Y, Yu H, Liu T, Feng X, Yu B, Zhang H, Wu J, Kong W, Yu X, Wu H
Cancers 2022 Jul 14;14(14)
Cancers 2022 Jul 14;14(14)
FUBP3 Degrades the Porcine Epidemic Diarrhea Virus Nucleocapsid Protein and Induces the Production of Type I Interferon.
Dong S, Kong N, Wang C, Li Y, Sun D, Qin W, Zhai H, Zhai X, Yang X, Ye C, Ye M, Liu C, Yu L, Zheng H, Tong W, Yu H, Zhang W, Tong G, Shan T
Journal of virology 2022 Jul 13;96(13):e0061822
Journal of virology 2022 Jul 13;96(13):e0061822
Nonstructural Protein NSs Activates Inflammasome and Pyroptosis through Interaction with NLRP3 in Human Microglial Cells Infected with Severe Fever with Thrombocytopenia Syndrome Bandavirus.
Gao C, Yu Y, Wen C, Li Z, Ding H, Qi X, Cardona CJ, Xing Z
Journal of virology 2022 Jul 13;96(13):e0016722
Journal of virology 2022 Jul 13;96(13):e0016722
Quantitative proteomic analysis of Bi Zhong Xiao decoction against collagen-induced arthritis rats in the early and late stages.
He C, Wang Y, Wen Y, Li T, Hu E, Zeng S, Xiong X
BMC complementary medicine and therapies 2022 Jul 13;22(1):186
BMC complementary medicine and therapies 2022 Jul 13;22(1):186
Transient neuroinflammation following surgery contributes to long-lasting cognitive decline in elderly rats via dysfunction of synaptic NMDA receptor.
Chen B, Qin G, Xiao J, Deng X, Lin A, Liu H
Journal of neuroinflammation 2022 Jul 13;19(1):181
Journal of neuroinflammation 2022 Jul 13;19(1):181
Mitochondrial Calcium-Triggered Oxidative Stress and Developmental Defects in Dopaminergic Neurons Differentiated from Deciduous Teeth-Derived Dental Pulp Stem Cells with MFF Insufficiency.
Sun X, Dong S, Kato H, Kong J, Ito Y, Hirofuji Y, Sato H, Kato TA, Sakai Y, Ohga S, Fukumoto S, Masuda K
Antioxidants (Basel, Switzerland) 2022 Jul 13;11(7)
Antioxidants (Basel, Switzerland) 2022 Jul 13;11(7)
PRIM2 Promotes Cell Cycle and Tumor Progression in p53-Mutant Lung Cancer.
Wang T, Tang T, Jiang Y, He T, Qi L, Chang H, Qiao Y, Sun M, Shan C, Zhu X, Liu J, Wang J
Cancers 2022 Jul 11;14(14)
Cancers 2022 Jul 11;14(14)
TFRC upregulation promotes ferroptosis in CVB3 infection via nucleus recruitment of Sp1.
Yi L, Hu Y, Wu Z, Li Y, Kong M, Kang Z, Zuoyuan B, Yang Z
Cell death & disease 2022 Jul 11;13(7):592
Cell death & disease 2022 Jul 11;13(7):592
Blocking glycine utilization inhibits multiple myeloma progression by disrupting glutathione balance.
Xia J, Zhang J, Wu X, Du W, Zhu Y, Liu X, Liu Z, Meng B, Guo J, Yang Q, Wang Y, Wang Q, Feng X, Xie G, Shen Y, He Y, Xiang J, Wu M, An G, Qiu L, Jia W, Zhou W
Nature communications 2022 Jul 11;13(1):4007
Nature communications 2022 Jul 11;13(1):4007
SULF2 enhances GDF15-SMAD axis to facilitate the initiation and progression of pancreatic cancer.
He R, Shi J, Xu D, Yang J, Shen Y, Jiang YS, Tao L, Yang M, Fu X, Yang JY, Liu D, Huo Y, Shen X, Lu P, Niu N, Sun YW, Xue J, Liu W
Cancer letters 2022 Jul 10;538:215693
Cancer letters 2022 Jul 10;538:215693
Combined exposure of lead and high-fat diet enhanced cognitive decline via interacting with CREB-BDNF signaling in male rats.
Liu R, Bai L, Liu M, Wang R, Wu Y, Li Q, Ba Y, Zhang H, Zhou G, Yu F, Huang H
Environmental pollution (Barking, Essex : 1987) 2022 Jul 1;304:119200
Environmental pollution (Barking, Essex : 1987) 2022 Jul 1;304:119200
Interleukin 7 inhibit autophagy via P53 regulated AMPK/mTOR signaling pathway in non-small cell lung cancer.
Zhu Y, Jiang X, Ding Z, Ming J
Scientific reports 2022 Jul 1;12(1):11208
Scientific reports 2022 Jul 1;12(1):11208
Activated AXL Protects Against Hepatic Ischemia-reperfusion Injury by Upregulating SOCS-1 Expression.
Wang Z, Liu D, Yan Q, Liu F, Zhan M, Qi S, Fang Q, Yao L, Wang W, Zhang R, Du J, Chen L
Transplantation 2022 Jul 1;106(7):1351-1364
Transplantation 2022 Jul 1;106(7):1351-1364
Knockdown of GBP1 inhibits BCG-induced apoptosis in macrophage RAW 264.7 cells via p38/JNK pathway.
Wang J, Liu Z, Li W, Yu J, Zhang D
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2022 Jan;97:105158
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2022 Jan;97:105158
Rosmarinic Acid Decreases the Malignancy of Pancreatic Cancer Through Inhibiting Gli1 Signaling.
Zhou X, Wang W, Li Z, Chen L, Wen C, Ruan Q, Xu Z, Liu R, Xu J, Bai Y, Deng J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153861
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153861
Moringa oleifera Lam. seed extract protects kidney function in rats with diabetic nephropathy by increasing GSK-3β activity and activating the Nrf2/HO-1 pathway.
Wen Y, Liu Y, Huang Q, Liu R, Liu J, Zhang F, Liu S, Jiang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153856
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153856
Ciliary Type III Adenylyl Cyclase in the VMH Is Crucial for High-Fat Diet-Induced Obesity Mediated by Autophagy.
Yang D, Wu X, Wang W, Zhou Y, Wang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jan;9(3):e2102568
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jan;9(3):e2102568
Ror2 mediates chronic post-thoracotomy pain by inducing the transformation of A1/A2 reactive astrocytes in rats.
Liu C, Shen L, Xu L, Zhu A, Huang Y
Cellular signalling 2022 Jan;89:110183
Cellular signalling 2022 Jan;89:110183
Galactose-decorated liver tumor-specific nanoliposomes incorporating selective BRD4-targeted PROTAC for hepatocellular carcinoma therapy.
Saraswat A, Vemana HP, Dukhande VV, Patel K
Heliyon 2022 Jan;8(1):e08702
Heliyon 2022 Jan;8(1):e08702
Resveratrol Improves Synaptic Plasticity in Hypoxic-Ischemic Brain Injury in Neonatal Mice via Alleviating SIRT1/NF-κB Signaling-Mediated Neuroinflammation.
Peng X, Wang J, Peng J, Jiang H, Le K
Journal of molecular neuroscience : MN 2022 Jan;72(1):113-125
Journal of molecular neuroscience : MN 2022 Jan;72(1):113-125
Inflammatory cell-derived CXCL3 promotes pancreatic cancer metastasis through a novel myofibroblast-hijacked cancer escape mechanism.
Sun X, He X, Zhang Y, Hosaka K, Andersson P, Wu J, Wu J, Jing X, Du Q, Hui X, Ding B, Guo Z, Hong A, Liu X, Wang Y, Ji Q, Beyaert R, Yang Y, Li Q, Cao Y
Gut 2022 Jan;71(1):129-147
Gut 2022 Jan;71(1):129-147
A calcium phosphate drug carrier loading with 5-fluorouracil achieving a synergistic effect for pancreatic cancer therapy.
Chen J, Qiu M, Zhang S, Li B, Li D, Huang X, Qian Z, Zhao J, Wang Z, Tang D
Journal of colloid and interface science 2022 Jan;605:263-273
Journal of colloid and interface science 2022 Jan;605:263-273
Exosomes from dental pulp cells attenuate bone loss in mouse experimental periodontitis.
Shimizu Y, Takeda-Kawaguchi T, Kuroda I, Hotta Y, Kawasaki H, Hariyama T, Shibata T, Akao Y, Kunisada T, Tatsumi J, Tezuka KI
Journal of periodontal research 2022 Jan;57(1):162-172
Journal of periodontal research 2022 Jan;57(1):162-172
Sorafenib attenuates liver fibrosis by triggering hepatic stellate cell ferroptosis via HIF-1α/SLC7A11 pathway.
Yuan S, Wei C, Liu G, Zhang L, Li J, Li L, Cai S, Fang L
Cell proliferation 2022 Jan;55(1):e13158
Cell proliferation 2022 Jan;55(1):e13158
Sestrin2 induction contributes to anti-inflammatory responses and cell survival by globular adiponectin in macrophages.
Lee S, Pham DV, Park PH
Archives of pharmacal research 2022 Jan;45(1):38-50
Archives of pharmacal research 2022 Jan;45(1):38-50
SIRT1 induces the accumulation of TAMs at colorectal cancer tumor sites via the CXCR4/CXCL12 axis.
Fang H, Huang Y, Luo Y, Tang J, Yu M, Zhang Y, Zhong M
Cellular immunology 2022 Jan;371:104458
Cellular immunology 2022 Jan;371:104458
The double-edged sword role of TGF-β signaling pathway between intrauterine inflammation and cranial neural crest development.
Li H, Long D, Lv G, Cheng X, Wang G, Yang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jan;36(1):e22113
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jan;36(1):e22113
Alnustone inhibits the growth of hepatocellular carcinoma via ROS- mediated PI3K/Akt/mTOR/p70S6K axis.
Wang L, Cheng L, Ma L, Ahmad Farooqi A, Qiao G, Zhang Y, Ye H, Liu M, Huang J, Yang X, Lin X, Cao S
Phytotherapy research : PTR 2022 Jan;36(1):525-542
Phytotherapy research : PTR 2022 Jan;36(1):525-542
Inhibition of progesterone receptor membrane component-1 exacerbates neonatal hypoxic-ischemic cerebral damage in male mice.
Sun X, Hu Y, Zhou H, Wang S, Zhou C, Lin L, Zhu T, Ge J, Han J, Zhou Y, Jin G, Wang Y, Zu J, Shi H, Yang X, Zan K, Wang J, Hua F
Experimental neurology 2022 Jan;347:113893
Experimental neurology 2022 Jan;347:113893
ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1.
Zhang T, Sun L, Hao Y, Suo C, Shen S, Wei H, Ma W, Zhang P, Wang T, Gu X, Li ST, Chen Z, Yan R, Zhang Y, Cai Y, Zhou R, Jia W, Huang F, Gao P, Zhang H
Nature cancer 2022 Jan;3(1):75-89
Nature cancer 2022 Jan;3(1):75-89
The deubiquitinase USP28 stabilizes the expression of RecQ family helicases and maintains the viability of triple negative breast cancer cells.
Wang J, Dong Y, Ma H, Wu L, Zhen X, Tang L, Jin J, Han S, Zhang P, Peng J
The Journal of biological chemistry 2022 Jan;298(1):101443
The Journal of biological chemistry 2022 Jan;298(1):101443
Electroacupuncture alleviates spatial memory deficits in METH withdrawal mice by enhancing astrocyte-mediated glutamate clearance in the dCA1.
He T, Li N, Shi P, Xu X, Nie J, Lu X, Yu P, Fan Y, Ge F, Guan X
Addiction biology 2022 Jan;27(1):e13068
Addiction biology 2022 Jan;27(1):e13068
Bcl-2 hijacks the arsenic trioxide resistance in SH-SY5Y cells.
Wang J, Peng X, Yang D, Guo M, Xu X, Yin F, Wang Y, Huang J, Zhan L, Qi Z
Journal of cellular and molecular medicine 2022 Jan;26(2):563-569
Journal of cellular and molecular medicine 2022 Jan;26(2):563-569
Immunoproteasome modulates NLRP3 inflammasome-mediated neuroinflammation under cerebral ischaemia and reperfusion conditions.
Chen X, Wang Y, Yao N, Lin Z
Journal of cellular and molecular medicine 2022 Jan;26(2):462-474
Journal of cellular and molecular medicine 2022 Jan;26(2):462-474
C1632 suppresses the migration and proliferation of non-small-cell lung cancer cells involving LIN28 and FGFR1 pathway.
Chen JY, Chen YJ, Liu L, Jin XX, Shen Z, Chen WB, Yang T, Xu SB, Wang GB, Cheng YN, Cheng DZ, Liu ZG, Zheng XH
Journal of cellular and molecular medicine 2022 Jan;26(2):422-435
Journal of cellular and molecular medicine 2022 Jan;26(2):422-435
Caveolin-1 negatively regulates inflammation and fibrosis in silicosis.
He R, Yuan X, Lv X, Liu Q, Tao L, Meng J
Journal of cellular and molecular medicine 2022 Jan;26(1):99-107
Journal of cellular and molecular medicine 2022 Jan;26(1):99-107
The critical role of B4GALT4 in promoting microtubule spindle assembly in HCC through the regulation of PLK1 and RHAMM expression.
Dai Z, Wang K, Gao Y
Journal of cellular physiology 2022 Jan;237(1):617-636
Journal of cellular physiology 2022 Jan;237(1):617-636
Role and mechanism of the Dectin-1-mediated Syk/NF-κB signaling pathway in Talaromyces marneffei infection.
Peng Y, Chen Y, Ma J, Zhou W, Wang Y, Wang Y, Zheng H, Shi W
Experimental and therapeutic medicine 2022 Jan;23(1):84
Experimental and therapeutic medicine 2022 Jan;23(1):84
Zinc-finger protein 750 mitigates malignant biological behavior of oral CSC-like cells enriched from parental CAL-27 cells.
Xu C, Yang HL, Yang YK, Pan L, Chen HY
Oncology letters 2022 Jan;23(1):28
Oncology letters 2022 Jan;23(1):28
DNMT3B regulates proliferation of A549 cells through the microRNA-152-3p/NCAM1 pathway.
Yang B, Huang S, Chen H, Li R, Hou S, Zhao J, Li Y
Oncology letters 2022 Jan;23(1):11
Oncology letters 2022 Jan;23(1):11
Deubiquitinase USP13 promotes the epithelial-mesenchymal transition and metastasis in gastric cancer by maintaining Snail protein.
Zhang T, Zheng J, Qiao L, Zhao W
Pathology, research and practice 2022 Jan;229:153705
Pathology, research and practice 2022 Jan;229:153705
Topical retinoic acid induces corneal strengthening by upregulating transglutaminase 2 in murine cornea.
Wu J, Wang J, Wang L, Huang Y
Experimental eye research 2022 Jan;214:108850
Experimental eye research 2022 Jan;214:108850
Morphological changes of macrophages and their potential contribution to tendon healing.
Yang QQ, Zhang L, Zhou YL, Tang JB
Colloids and surfaces. B, Biointerfaces 2022 Jan;209(Pt 1):112145
Colloids and surfaces. B, Biointerfaces 2022 Jan;209(Pt 1):112145
MICAL1 inhibits colorectal cancer cell migration and proliferation by regulating the EGR1/β-catenin signaling pathway.
Gu H, Li Y, Cui X, Cao H, Hou Z, Ti Y, Liu D, Gao J, Wang Y, Wen P
Biochemical pharmacology 2022 Jan;195:114870
Biochemical pharmacology 2022 Jan;195:114870
METTL3 Regulates Liver Homeostasis, Hepatocyte Ploidy, and Circadian Rhythm-Controlled Gene Expression in Mice.
Barajas JM, Lin CH, Sun HL, Alencastro F, Zhu AC, Aljuhani M, Navari L, Yilmaz SA, Yu L, Corps K, He C, Duncan AW, Ghoshal K
The American journal of pathology 2022 Jan;192(1):56-71
The American journal of pathology 2022 Jan;192(1):56-71
Pyridoxamine ameliorates methylglyoxal-induced macrophage dysfunction to facilitate tissue repair in diabetic wounds.
Jiang M, Yakupu A, Guan H, Dong J, Liu Y, Song F, Tang J, Tian M, Niu Y, Lu S
International wound journal 2022 Jan;19(1):52-63
International wound journal 2022 Jan;19(1):52-63
RNF2 promotes the progression of colon cancer by regulating ubiquitination and degradation of IRF4.
Wang J, Ouyang X, Zhou Z, Mao S, Niu X, Li H, Xu W, Song Y, Cao J, Lai B
Biochimica et biophysica acta. Molecular cell research 2022 Jan;1869(1):119162
Biochimica et biophysica acta. Molecular cell research 2022 Jan;1869(1):119162
Carrier-Free Delivery of Ultrasmall π-Conjugated Oligomer Nanoparticles with Photothermal Conversion over 80% for Cancer Theranostics.
Zheng R, Zhao Q, Qing W, Li S, Liu Z, Li Q, Huang Y
Small (Weinheim an der Bergstrasse, Germany) 2022 Jan;18(4):e2104521
Small (Weinheim an der Bergstrasse, Germany) 2022 Jan;18(4):e2104521
Silencing TXNIP ameliorates high uric acid-induced insulin resistance via the IRS2/AKT and Nrf2/HO-1 pathways in macrophages.
Yu W, Chen C, Zhuang W, Wang W, Liu W, Zhao H, Lv J, Xie D, Wang Q, He F, Xu C, Chen B, Yamamoto T, Koyama H, Cheng J
Free radical biology & medicine 2022 Jan;178:42-53
Free radical biology & medicine 2022 Jan;178:42-53
Silent information regulator 1 ameliorates oxidative stress injury via PGC-1α/PPARγ-Nrf2 pathway after ischemic stroke in rat.
Zhou Y, Peng L, Li Y, Zhao Y
Brain research bulletin 2022 Jan;178:37-48
Brain research bulletin 2022 Jan;178:37-48
Mettl3 inhibits the apoptosis and autophagy of chondrocytes in inflammation through mediating Bcl2 stability via Ythdf1-mediated m(6)A modification.
He Y, Wang W, Xu X, Yang B, Yu X, Wu Y, Wang J
Bone 2022 Jan;154:116182
Bone 2022 Jan;154:116182
Overexpression of DOCK6 in oral squamous cell cancer promotes cellular migration and invasion and is associated with poor prognosis.
Zhang ZY, Sun YY, Wang HC, Fu WN, Sun CF
Archives of oral biology 2022 Jan;133:105297
Archives of oral biology 2022 Jan;133:105297
Injectable hyaluronic acid hydrogel loaded with BMSC and NGF for traumatic brain injury treatment.
Wang L, Zhang D, Ren Y, Guo S, Li J, Ma S, Yao M, Guan F
Materials today. Bio 2022 Jan;13:100201
Materials today. Bio 2022 Jan;13:100201
Characterization and function of mandarin fish c-Myc during viral infection process.
Ye C, Li N, Niu Y, Lin Q, Luo X, Liang H, Liu L, Fu X
Fish & shellfish immunology 2022 Jan;120:686-694
Fish & shellfish immunology 2022 Jan;120:686-694
Lysyl oxidase promotes anaplastic thyroid carcinoma cell proliferation and metastasis mediated via BMP1.
Liu Y, Zhang Y, Tan Z, Wang J, Hu Y, Sun J, Bao M, Huang P, Ge M, Chai YJ, Zheng C
Gland surgery 2022 Jan;11(1):245-257
Gland surgery 2022 Jan;11(1):245-257
Cotargeting of Bcl-2 and Mcl-1 shows promising antileukemic activity against AML cells including those with acquired cytarabine resistance.
Liu F, Zhao Q, Su Y, Lv J, Gai Y, Liu S, Lin H, Wang Y, Wang G
Experimental hematology 2022 Jan;105:39-49
Experimental hematology 2022 Jan;105:39-49
BPIFA2 as a Novel Early Biomarker to Identify Fatal Radiation Injury After Radiation Exposure.
He L, Zhou S, Li W, Wang Q, Qi Z, Zhou P, Wang Z, Chen J, Li Y, Lin Z
Dose-response : a publication of International Hormesis Society 2022 Jan-Mar;20(1):15593258221086478
Dose-response : a publication of International Hormesis Society 2022 Jan-Mar;20(1):15593258221086478
Effect of Ultraviolet B Irradiation on Melanin Content Accompanied by the Activation of p62/GATA4-Mediated Premature Senescence in HaCaT Cells.
Yan J, Ma LP, Liu F, Sun B, Tian M, Lu X, Liu HX, Gao L, Liu QJ
Dose-response : a publication of International Hormesis Society 2022 Jan-Mar;20(1):15593258221075321
Dose-response : a publication of International Hormesis Society 2022 Jan-Mar;20(1):15593258221075321
Enhancement of Acylcarnitine Levels in Small Intestine of Abdominal Irradiation Rats Might Relate to Fatty Acid β-Oxidation Pathway Disequilibration.
Liu HX, Lu X, Zhao H, Li S, Gao L, Tian M, Liu QJ
Dose-response : a publication of International Hormesis Society 2022 Jan-Mar;20(1):15593258221075118
Dose-response : a publication of International Hormesis Society 2022 Jan-Mar;20(1):15593258221075118
HSP90AB1 Promotes the Proliferation, Migration, and Glycolysis of Head and Neck Squamous Cell Carcinoma.
Zhang H, Yin X, Zhang X, Zhou M, Xu W, Wei Z, Song C, Han S, Han W
Technology in cancer research & treatment 2022 Jan-Dec;21:15330338221118202
Technology in cancer research & treatment 2022 Jan-Dec;21:15330338221118202
Spinal 5-HT(2A) receptor is involved in electroacupuncture inhibition of chronic pain.
Yuan XC, Wang YY, Tian LX, Yan XJ, Guo YX, Zhao YL, Baba SS, Jia H, Wang HS, Li M, Huo FQ
Molecular pain 2022 Jan-Dec;18:17448069221087583
Molecular pain 2022 Jan-Dec;18:17448069221087583
A virulence factor as a therapeutic: the probiotic Enterococcus faecium SF68 arginine deiminase inhibits innate immune signaling pathways.
Ghazisaeedi F, Meens J, Hansche B, Maurischat S, Schwerk P, Goethe R, Wieler LH, Fulde M, Tedin K
Gut microbes 2022 Jan-Dec;14(1):2106105
Gut microbes 2022 Jan-Dec;14(1):2106105
ROS/PI3K/Akt and Wnt/β-catenin signalings activate HIF-1α-induced metabolic reprogramming to impart 5-fluorouracil resistance in colorectal cancer.
Dong S, Liang S, Cheng Z, Zhang X, Luo L, Li L, Zhang W, Li S, Xu Q, Zhong M, Zhu J, Zhang G, Hu S
Journal of experimental & clinical cancer research : CR 2022 Jan 8;41(1):15
Journal of experimental & clinical cancer research : CR 2022 Jan 8;41(1):15
ERK/p38/ROS burst responses to environmentally relevant concentrations of diphenyl phosphate-evoked neutrophil extracellular traps formation: Assessing the role of autophagy.
Li S, Ma Y, Ye S, Hu D, Xiao F
Journal of hazardous materials 2022 Jan 5;421:126758
Journal of hazardous materials 2022 Jan 5;421:126758
CHMFL-BMX-078, a BMX inhibitor, overcomes the resistance of melanoma to vemurafenib via inhibiting AKT pathway.
Jiang S, Jiang T, Huang H, Chen X, Li L, Wang Z, Fei J, Liu C, Liu Z, Cheng Y
Chemico-biological interactions 2022 Jan 5;351:109747
Chemico-biological interactions 2022 Jan 5;351:109747
High salt activates p97 to reduce host antiviral immunity by restricting Viperin induction.
Yuan Y, Miao Y, Ren T, Huang F, Qian L, Chen X, Zuo Y, Zhang HG, He J, Qiao C, Du Q, Wu Q, Zhang W, Zhu C, Xu Y, Wu D, Shi W, Jiang J, Xu G, Zheng H
EMBO reports 2022 Jan 5;23(1):e53466
EMBO reports 2022 Jan 5;23(1):e53466
Novel 5-fluorouracil sensitizers for colorectal cancer therapy: Design and synthesis of S1P receptor 2 (S1PR2) antagonists.
Luo D, Guo Z, Zhao X, Wu L, Liu X, Zhang Y, Zhang Y, Deng Z, Qu X, Cui S, Wan S
European journal of medicinal chemistry 2022 Jan 5;227:113923
European journal of medicinal chemistry 2022 Jan 5;227:113923
SIRT6 protects vascular smooth muscle cells from osteogenic transdifferentiation via Runx2 in chronic kidney disease.
Li W, Feng W, Su X, Luo D, Li Z, Zhou Y, Zhu Y, Zhang M, Chen J, Liu B, Huang H
The Journal of clinical investigation 2022 Jan 4;132(1)
The Journal of clinical investigation 2022 Jan 4;132(1)
Urolithin A protects dopaminergic neurons in experimental models of Parkinson's disease by promoting mitochondrial biogenesis through the SIRT1/PGC-1α signaling pathway.
Liu J, Jiang J, Qiu J, Wang L, Zhuo J, Wang B, Sun D, Yu S, Lou H
Food & function 2022 Jan 4;13(1):375-385
Food & function 2022 Jan 4;13(1):375-385
The association of telomere maintenance and TERT expression with susceptibility to human papillomavirus infection in cervical epithelium.
Wang LN, Wang L, Cheng G, Dai M, Yu Y, Teng G, Zhao J, Xu D
Cellular and molecular life sciences : CMLS 2022 Jan 31;79(2):110
Cellular and molecular life sciences : CMLS 2022 Jan 31;79(2):110
m6A modifications regulate intestinal immunity and rotavirus infection.
Wang A, Tao W, Tong J, Gao J, Wang J, Hou G, Qian C, Zhang G, Li R, Wang D, Ren X, Zhang K, Ding S, Flavell RA, Li H, Pan W, Zhu S
eLife 2022 Jan 31;11
eLife 2022 Jan 31;11
Metastasis suppressor 1 controls osteoblast differentiation and bone homeostasis through regulating Src-Wnt/β-catenin signaling.
Chen M, Shan L, Gan Y, Tian L, Zhou J, Zhu E, Yuan H, Li X, Wang B
Cellular and molecular life sciences : CMLS 2022 Jan 30;79(2):107
Cellular and molecular life sciences : CMLS 2022 Jan 30;79(2):107
Saponins from Nigella glandulifera seeds attenuate collagen-induced rheumatoid arthritis in rats via the OPG/RANKL/NF-κB and Ang/Tie-2 pathways.
Jiang H, Xu F, Zeng L, Li C, Chen Y, Wang L, Li Z, Liu R
Journal of ethnopharmacology 2022 Jan 30;283:114714
Journal of ethnopharmacology 2022 Jan 30;283:114714
Guizhi-Shaoyao-Zhimu decoction attenuates monosodium urate crystal-induced inflammation through inactivation of NF-κB and NLRP3 inflammasome.
Zhou GQ, Chen G, Yang J, Qin WY, Ping J
Journal of ethnopharmacology 2022 Jan 30;283:114707
Journal of ethnopharmacology 2022 Jan 30;283:114707
The ethanol extract of flower buds of Tussilago farfara L. attenuates cigarette smoke-induced lung inflammation through regulating NLRP3 inflammasome, Nrf2, and NF-κB.
Xu LT, Wang T, Fang KL, Zhao Y, Wang XN, Ren DM, Shen T
Journal of ethnopharmacology 2022 Jan 30;283:114694
Journal of ethnopharmacology 2022 Jan 30;283:114694
A Novel Rat Model of Dry Eye Induced by Aerosol Exposure of Particulate Matter.
Mu N, Wang H, Chen D, Wang F, Ji L, Zhang C, Li M, Lu P
Investigative ophthalmology & visual science 2022 Jan 3;63(1):39
Investigative ophthalmology & visual science 2022 Jan 3;63(1):39
Ketogenic diet ameliorates lipid dysregulation in type 2 diabetic mice by downregulating hepatic pescadillo 1.
Zhou J, Lu Y, Jia Y, Lu J, Jiang Z, Chen K
Molecular medicine (Cambridge, Mass.) 2022 Jan 3;28(1):1
Molecular medicine (Cambridge, Mass.) 2022 Jan 3;28(1):1
CBX4-dependent regulation of HDAC3 nuclear translocation reduces Bmp2-induced osteoblastic differentiation and calcification in adamantinomatous craniopharyngioma.
Yan X, Kang D, Lin Y, Qi S, Jiang C
Cell communication and signaling : CCS 2022 Jan 3;20(1):3
Cell communication and signaling : CCS 2022 Jan 3;20(1):3
Hyaluronic Acid-Modified Nanoparticles Self-Assembled from Linoleic Acid-Conjugated Chitosan for the Codelivery of miR34a and Doxorubicin in Resistant Breast Cancer.
Yang X, Shang P, Ji J, Malichewe C, Yao Z, Liao J, Du D, Sun C, Wang L, Tang YJ, Guo X
Molecular pharmaceutics 2022 Jan 3;19(1):2-17
Molecular pharmaceutics 2022 Jan 3;19(1):2-17
Long non-coding RNA lncC11orf54-1 modulates neuroinflammatory responses by activating NF-κB signaling during meningitic Escherichia coli infection.
Xu B, Yang R, Yang B, Li L, Chen J, Fu J, Qu X, Huo D, Tan C, Chen H, Peng Z, Wang X
Molecular brain 2022 Jan 3;15(1):4
Molecular brain 2022 Jan 3;15(1):4
Ginsenoside compound K acts via LRP1 to alleviate Amyloid β(42)-induced neuroinflammation in microglia by suppressing NF-κB.
Jiao H, Jia J
Biochemical and biophysical research communications 2022 Jan 29;590:14-19
Biochemical and biophysical research communications 2022 Jan 29;590:14-19
Actin nucleator formins regulate the tension-buffering function of caveolin-1.
Shi X, Tang D, Xing Y, Zhao S, Fan C, Zhong J, Cui Y, Shi K, Jiu Y
Journal of molecular cell biology 2022 Jan 29;13(12):876-888
Journal of molecular cell biology 2022 Jan 29;13(12):876-888
LINC01119 negatively regulates osteogenic differentiation of mesenchymal stem cells via the Wnt pathway by targeting FZD4.
Gao H, Dong H, Zheng J, Jiang X, Gong M, Hu L, He J, Wang Y
Stem cell research & therapy 2022 Jan 29;13(1):43
Stem cell research & therapy 2022 Jan 29;13(1):43
Steroid-sensitive nephrotic syndrome candidate gene CLVS1 regulates podocyte oxidative stress and endocytosis.
Lane BM, Chryst-Stangl M, Wu G, Shalaby M, El Desoky S, Middleton CC, Huggins K, Sood A, Ochoa A, Malone AF, Vancini R, Miller SE, Hall G, Kim SY, Howell DN, Kari JA, Gbadegesin R
JCI insight 2022 Jan 25;7(2)
JCI insight 2022 Jan 25;7(2)
Role of Sleep Restriction in Daily Rhythms of Expression of Hypothalamic Core Clock Genes in Mice.
Li W, Wang Z, Cao J, Dong Y, Chen Y
Current issues in molecular biology 2022 Jan 25;44(2):609-625
Current issues in molecular biology 2022 Jan 25;44(2):609-625
Structure and transport mechanism of the human cholesterol transporter ABCG1.
Xu D, Li Y, Yang F, Sun CR, Pan J, Wang L, Chen ZP, Fang SC, Yao X, Hou WT, Zhou CZ, Chen Y
Cell reports 2022 Jan 25;38(4):110298
Cell reports 2022 Jan 25;38(4):110298
The Mitochondrial PHB2/OMA1/DELE1 Pathway Cooperates with Endoplasmic Reticulum Stress to Facilitate the Response to Chemotherapeutics in Ovarian Cancer.
Cheng M, Yu H, Kong Q, Wang B, Shen L, Dong D, Sun L
International journal of molecular sciences 2022 Jan 25;23(3)
International journal of molecular sciences 2022 Jan 25;23(3)
Integrative bioinformatics and experimental analysis revealed TEAD as novel prognostic target for hepatocellular carcinoma and its roles in ferroptosis regulation.
Ren X, Wang X, Yan Y, Chen X, Cai Y, Liang Q, Peng B, Xu Z, He Q, Kang F, Li J, Zhang W, Hong Q, Peng J, Xiao M
Aging 2022 Jan 25;14(2):961-974
Aging 2022 Jan 25;14(2):961-974
Modular assembly of the principal microtubule nucleator γ-TuRC.
Würtz M, Zupa E, Atorino ES, Neuner A, Böhler A, Rahadian AS, Vermeulen BJA, Tonon G, Eustermann S, Schiebel E, Pfeffer S
Nature communications 2022 Jan 25;13(1):473
Nature communications 2022 Jan 25;13(1):473
SARS-CoV-2 NSP5 and N protein counteract the RIG-I signaling pathway by suppressing the formation of stress granules.
Zheng Y, Deng J, Han L, Zhuang MW, Xu Y, Zhang J, Nan ML, Xiao Y, Zhan P, Liu X, Gao C, Wang PH
Signal transduction and targeted therapy 2022 Jan 24;7(1):22
Signal transduction and targeted therapy 2022 Jan 24;7(1):22
Sodium hydrosulfide reverses β(2)-microglobulin-induced depressive-like behaviors of male Sprague-Dawley rats: Involving improvement of synaptic plasticity and enhancement of Warburg effect in hippocampus.
Yang SQ, Tang YY, Zeng D, Tian Q, Wei HJ, Wang CY, Zhang P, Chen YJ, Zou W, Tang XQ
Behavioural brain research 2022 Jan 24;417:113562
Behavioural brain research 2022 Jan 24;417:113562
Salubrinal protects against inflammatory response in macrophage and attenuates psoriasiform skin inflammation by antagonizing NF-κB signaling pathway.
Shangguan Y, Chen Y, Ma Y, Zhao Y, He Y, Li W
Biochemical and biophysical research communications 2022 Jan 22;589:63-70
Biochemical and biophysical research communications 2022 Jan 22;589:63-70
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone provokes progression from chronic pancreatitis to pancreatic intraepithelial neoplasia.
Chen X, Sheng L, Ma J, Qi D, Li X, Wang Z, Wu Z, Wong L, Huang JH, Wu E, Ma Q, Zhang D
iScience 2022 Jan 21;25(1):103647
iScience 2022 Jan 21;25(1):103647
Pyk2 suppresses contextual fear memory in an autophosphorylation-independent manner.
Zheng J, Suo L, Zhou Y, Jia L, Li J, Kuang Y, Cui D, Zhang X, Wu Q
Journal of molecular cell biology 2022 Jan 21;13(11):808-821
Journal of molecular cell biology 2022 Jan 21;13(11):808-821
Benzaldehyde Attenuates the Fifth Stage Larval Excretory-Secretory Product of Angiostrongylus cantonensis-Induced Injury in Mouse Astrocytes via Regulation of Endoplasmic Reticulum Stress and Oxidative Stress.
Chen KY, Chen YJ, Cheng CJ, Jhan KY, Wang LC
Biomolecules 2022 Jan 21;12(2)
Biomolecules 2022 Jan 21;12(2)
Epimedium protects against dyszoospermia in mice with Pex3 knockout by exerting antioxidant effects and regulating the expression level of P16.
Zhao H, Zhao T, Yang J, Huang Q, Wu H, Pan Y, Wang H, Qian Y
Cell death & disease 2022 Jan 20;13(1):69
Cell death & disease 2022 Jan 20;13(1):69
PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells by phosphorylating PRAS40.
Zhang T, Wang Y, Yu H, Zhang T, Guo L, Xu J, Wei X, Wang N, Wu Y, Wang X, Huang L
Cell death & disease 2022 Jan 20;13(1):68
Cell death & disease 2022 Jan 20;13(1):68
Extracellular vesicles from adipose-derived stem cells promote microglia M2 polarization and neurological recovery in a mouse model of transient middle cerebral artery occlusion.
Hu X, Pan J, Li Y, Jiang Y, Zheng H, Shi R, Zhang Q, Liu C, Tian H, Zhang Z, Tang Y, Yang GY, Wang Y
Stem cell research & therapy 2022 Jan 20;13(1):21
Stem cell research & therapy 2022 Jan 20;13(1):21
Pulsed electromagnetic field alleviates synovitis and inhibits the NLRP3/Caspase-1/GSDMD signaling pathway in osteoarthritis rats.
Liu J, Huang X, Zhou J, Li L, Xiao H, Qu M, Sun Z
Electromagnetic biology and medicine 2022 Jan 2;41(1):101-107
Electromagnetic biology and medicine 2022 Jan 2;41(1):101-107
4,5-Dimethoxycanthin-6-one is a novel LSD1 inhibitor that inhibits proliferation of glioblastoma cells and induces apoptosis and pyroptosis.
Li W, Huang BS, Xiong YY, Yang LJ, Wu LX
Cancer cell international 2022 Jan 18;22(1):32
Cancer cell international 2022 Jan 18;22(1):32
PDGF-D-PDGFRβ signaling enhances IL-15-mediated human natural killer cell survival.
Ma S, Tang T, Wu X, Mansour AG, Lu T, Zhang J, Wang LS, Caligiuri MA, Yu J
Proceedings of the National Academy of Sciences of the United States of America 2022 Jan 18;119(3)
Proceedings of the National Academy of Sciences of the United States of America 2022 Jan 18;119(3)
Genome-wide CRISPR/Cas9 library screen identifies PCMT1 as a critical driver of ovarian cancer metastasis.
Zhang J, Li Y, Liu H, Zhang J, Wang J, Xia J, Zhang Y, Yu X, Ma J, Huang M, Wang J, Wang L, Li Q, Cui R, Yang W, Xu Y, Feng W
Journal of experimental & clinical cancer research : CR 2022 Jan 15;41(1):24
Journal of experimental & clinical cancer research : CR 2022 Jan 15;41(1):24
The amino acids of Autographa californica multiple nucleopolyhedrovirus P48 critical for the association with Ac93 are important for the nuclear egress of nucleocapsids and efficient formation of intranuclear microvesicles.
Wang Y, He J, Mo M, Cai Q, Wu W, Yuan M, Yang K
Virus research 2022 Jan 15;308:198644
Virus research 2022 Jan 15;308:198644
Ellagic acid ameliorates paraquat-induced liver injury associated with improved gut microbial profile.
Qi M, Wang N, Xiao Y, Deng Y, Zha A, Tan B, Wang J, Yin Y, Liao P
Environmental pollution (Barking, Essex : 1987) 2022 Jan 15;293:118572
Environmental pollution (Barking, Essex : 1987) 2022 Jan 15;293:118572
Identification of G protein-coupled receptor 55 (GPR55) as a target of curcumin.
Harada N, Okuyama M, Teraoka Y, Arahori Y, Shinmori Y, Horiuchi H, Luis PB, Joseph AI, Kitakaze T, Matsumura S, Hira T, Yamamoto N, Iuni T, Goshima N, Schneider C, Inui H, Yamaji R
NPJ science of food 2022 Jan 14;6(1):4
NPJ science of food 2022 Jan 14;6(1):4
The PERK/PKR-eIF2α Pathway Negatively Regulates Porcine Hemagglutinating Encephalomyelitis Virus Replication by Attenuating Global Protein Translation and Facilitating Stress Granule Formation.
Shi J, Li Z, Xu R, Zhang J, Zhou Q, Gao R, Lu H, Lan Y, Zhao K, He H, Gao F, He W
Journal of virology 2022 Jan 12;96(1):e0169521
Journal of virology 2022 Jan 12;96(1):e0169521
Extracellular vesicles derived from glioblastoma promote proliferation and migration of neural progenitor cells via PI3K-Akt pathway.
Pan J, Sheng S, Ye L, Xu X, Ma Y, Feng X, Qiu L, Fan Z, Wang Y, Xia X, Zheng JC
Cell communication and signaling : CCS 2022 Jan 12;20(1):7
Cell communication and signaling : CCS 2022 Jan 12;20(1):7
The Effects of Intraoperative Hypothermia on Postoperative Cognitive Function in the Rat Hippocampus and Its Possible Mechanisms.
Xu G, Li T, Huang Y
Brain sciences 2022 Jan 12;12(1)
Brain sciences 2022 Jan 12;12(1)
Selenium Induces Pancreatic Cancer Cell Death Alone and in Combination with Gemcitabine.
Wooten DJ, Sinha I, Sinha R
Biomedicines 2022 Jan 11;10(1)
Biomedicines 2022 Jan 11;10(1)
Anti-tumor effect of Yanggan Huayu granule by inducing AKT-mediated apoptosis in hepatocellular carcinoma.
Shen Y, Yang F, Peng H, Zhang G, Zhu F, Xu H, Shi L
Journal of ethnopharmacology 2022 Jan 10;282:114601
Journal of ethnopharmacology 2022 Jan 10;282:114601
Tanshinone IIA alleviates NLRP3 inflammasome-mediated pyroptosis in Mycobacterium tuberculosis-(H37Ra-) infected macrophages by inhibiting endoplasmic reticulum stress.
Li Y, Fu Y, Sun J, Shen J, Liu F, Ning B, Lu Z, Wei L, Jiang X
Journal of ethnopharmacology 2022 Jan 10;282:114595
Journal of ethnopharmacology 2022 Jan 10;282:114595
Xiaoyao powder improves endometrial receptivity via VEGFR-2-mediated angiogenesis through the activation of the JNK and P38 signaling pathways.
He M, Li L, Wei X, Geng D, Jiang H, Xiangxiang G, Zhang Y, Du H
Journal of ethnopharmacology 2022 Jan 10;282:114580
Journal of ethnopharmacology 2022 Jan 10;282:114580
Overexpression of Lin28a induces a primary ovarian insufficiency phenotype via facilitation of primordial follicle activation in mice.
Chen J, Liu W, Lee KF, Liu K, Wong BPC, Shu-Biu Yeung W
Molecular and cellular endocrinology 2022 Jan 1;539:111460
Molecular and cellular endocrinology 2022 Jan 1;539:111460
Ligature induced periodontitis in rats causes gut dysbiosis leading to hepatic injury through SCD1/AMPK signalling pathway.
Xing T, Liu Y, Cheng H, Bai M, Chen J, Ji H, He M, Chen K
Life sciences 2022 Jan 1;288:120162
Life sciences 2022 Jan 1;288:120162
Role of notch signaling pathway in Muc5ac secretion induced by atmospheric PM(2.5) in rats.
Liu Y, Zhou L, Wu H, Wang Y, Danzengluobu, Zhang B
Ecotoxicology and environmental safety 2022 Jan 1;229:113052
Ecotoxicology and environmental safety 2022 Jan 1;229:113052
PTP70-2, a novel polysaccharide from Polygala tenuifolia, prevents neuroinflammation and protects neurons by suppressing the TLR4-mediated MyD88/NF-κB signaling pathway.
Chen H, Zhong J, Li J, Zeng Z, Yu Q, Yan C
International journal of biological macromolecules 2022 Jan 1;194:546-555
International journal of biological macromolecules 2022 Jan 1;194:546-555
Agrimoniin sensitizes pancreatic cancer to apoptosis through ROS-mediated energy metabolism dysfunction.
Zhu X, Zhang Y, Wang Y, Zhang H, Wang X, Tang H, Huang H, Zhou Z, Chen B, Sun L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153807
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153807
Sleeve gastrectomy suppresses hepatic de novo cholesterogenesis and improves hepatic cholesterol accumulation in obese rats with type 2 diabetes mellitus.
Chen F, Liu B
Nutrition (Burbank, Los Angeles County, Calif.) 2022 Feb;94:111531
Nutrition (Burbank, Los Angeles County, Calif.) 2022 Feb;94:111531
Transgelin-2 interacts with CD44 to regulate Notch1 signaling pathway and participates in colorectal cancer proliferation and migration.
Ding R, Li G, Yao Y, Zhang L, Zhang X, Li J, Shen T, Gao Y, Wu T, Kong S, Huang M, Li Y
Journal of physiology and biochemistry 2022 Feb;78(1):99-108
Journal of physiology and biochemistry 2022 Feb;78(1):99-108
NPC1-regulated dynamic of clathrin-coated pits is essential for viral entry.
Li G, Su B, Fu P, Bai Y, Ding G, Li D, Wang J, Yang G, Chu B
Science China. Life sciences 2022 Feb;65(2):341-361
Science China. Life sciences 2022 Feb;65(2):341-361
Notch activation suppresses endothelial cell migration and sprouting via miR-223-3p targeting Fbxw7.
Wang R, Yang Z, Liang L, Feng X, Che B, Zhang X, Zheng Q, Yan X, Han H
In vitro cellular & developmental biology. Animal 2022 Feb;58(2):124-135
In vitro cellular & developmental biology. Animal 2022 Feb;58(2):124-135
The IFN-inducible GTPase IRGB10 regulates viral replication and inflammasome activation during influenza A virus infection in mice.
Christgen S, Place DE, Zheng M, Briard B, Yamamoto M, Kanneganti TD
European journal of immunology 2022 Feb;52(2):285-296
European journal of immunology 2022 Feb;52(2):285-296
Benchmarking a highly selective USP30 inhibitor for enhancement of mitophagy and pexophagy.
Rusilowicz-Jones EV, Barone FG, Lopes FM, Stephen E, Mortiboys H, Urbé S, Clague MJ
Life science alliance 2022 Feb;5(2)
Life science alliance 2022 Feb;5(2)
Induction of estrogen receptor β-mediated autophagy sensitizes breast cancer cells to TAD1822-7, a novel biphenyl urea taspine derivative.
Su Q, Wu Q, Chen K, Wang J, Sarwar A, Zhang Y
Molecular biology reports 2022 Feb;49(2):1223-1232
Molecular biology reports 2022 Feb;49(2):1223-1232
PDCD4 Simultaneously Promotes Microglia Activation via PDCD4-MAPK-NF-κB Positive Loop and Facilitates Neuron Apoptosis During Neuroinflammation.
Chen Q, Lu H, Duan C, Zhu X, Zhang Y, Li M, Zhang D
Inflammation 2022 Feb;45(1):234-252
Inflammation 2022 Feb;45(1):234-252
Methylene blue prevents osteoarthritis progression and relieves pain in rats via upregulation of Nrf2/PRDX1.
Li JW, Wang RL, Xu J, Sun KY, Jiang HM, Sun ZY, Lv ZY, Xu XQ, Wu R, Guo H, Jiang Q, Shi DQ
Acta pharmacologica Sinica 2022 Feb;43(2):417-428
Acta pharmacologica Sinica 2022 Feb;43(2):417-428
An IgD-Fc-Ig fusion protein restrains the activation of T and B cells by inhibiting IgD-IgDR-Lck signaling in rheumatoid arthritis.
Hu XX, Zhang AJ, Pan WW, Xin QL, Chen JY, Zhang LL, Chang Y, Wu YJ, Wei W
Acta pharmacologica Sinica 2022 Feb;43(2):387-400
Acta pharmacologica Sinica 2022 Feb;43(2):387-400
Ginsenoside Rb1 alleviates diabetic kidney podocyte injury by inhibiting aldose reductase activity.
He JY, Hong Q, Chen BX, Cui SY, Liu R, Cai GY, Guo J, Chen XM
Acta pharmacologica Sinica 2022 Feb;43(2):342-353
Acta pharmacologica Sinica 2022 Feb;43(2):342-353
Malic enzyme 2 maintains protein stability of mutant p53 through 2-hydroxyglutarate.
Zhao M, Yao P, Mao Y, Wu J, Wang W, Geng C, Cheng J, Du W, Jiang P
Nature metabolism 2022 Feb;4(2):225-238
Nature metabolism 2022 Feb;4(2):225-238
Establishment of a pseudovirus neutralization assay based on SARS-CoV-2 S protein incorporated into lentiviral particles.
Wang S, Liu L, Wang C, Wang Z, Duan X, Chen G, Zhou H, Shao H
Biosafety and health 2022 Feb;4(1):38-44
Biosafety and health 2022 Feb;4(1):38-44
Estrogen receptor beta increases clear cell renal cell carcinoma stem cell phenotype via altering the circPHACTR4/miR-34b-5p/c-Myc signaling.
Wang Y, Yang Z, Gu J, Zhang Y, Wang X, Teng Z, Wang D, Gao L, Li W, Yeh S, Han Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Feb;36(2):e22163
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Feb;36(2):e22163
Spindle pole body component 24 homolog potentiates tumor progression via regulation of SRY-box transcription factor 2 in clear cell renal cell carcinoma.
Sun C, Wei J, Long Z, Zhao W, Huangfu Q, Xie Q, Wang B, Wen J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Feb;36(2):e22086
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Feb;36(2):e22086
Activation of PGC-1α via isoliquiritigenin-induced downregulation of miR-138-5p alleviates nonalcoholic fatty liver disease.
Wang L, Wang X, Kong L, Li Y, Huang K, Wu J, Wang C, Sun H, Sun P, Gu J, Luo H, Liu K, Meng Q
Phytotherapy research : PTR 2022 Feb;36(2):899-913
Phytotherapy research : PTR 2022 Feb;36(2):899-913
Exogenous melatonin prevents type 1 diabetes mellitus-induced bone loss, probably by inhibiting senescence.
Gong Z, Da W, Tian Y, Zhao R, Qiu S, Wu Q, Wen K, Shen L, Zhou R, Tao L, Zhu Y
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2022 Feb;33(2):453-466
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2022 Feb;33(2):453-466
Neuroglobin expression and function in the temporal cortex of bilirubin encephalopathy rats.
Hu JH, Fan P, Zhang LR, Chen CY, Xu J, Huang J, Lu WT, Zhu SJ, Qiu GP, Xu SY, Ran JH, Gan SW
Anatomical record (Hoboken, N.J. : 2007) 2022 Feb;305(2):254-264
Anatomical record (Hoboken, N.J. : 2007) 2022 Feb;305(2):254-264
Cryo-EM structure of mouse TRPML2 in lipid nanodiscs.
Song X, Li J, Tian M, Zhu H, Hu X, Zhang Y, Cao Y, Ye H, McCormick PJ, Zeng B, Fu Y, Duan J, Zhang J
The Journal of biological chemistry 2022 Feb;298(2):101487
The Journal of biological chemistry 2022 Feb;298(2):101487
Differential expression of long non-coding RNAs in the hippocampus of mice exposed to PM(2.5) in Dalian, China.
Li J, Zhang L, Wang J, Jia R, Zhang X, Li X, Fu Y, Song L
Environmental science and pollution research international 2022 Feb;29(8):12136-12146
Environmental science and pollution research international 2022 Feb;29(8):12136-12146
G protein-coupled receptor 17 restricts rabies virus replication via BAK-mediated apoptosis.
Liu W, Yang Y, Zeng Z, Tian Y, Wu Q, Zhou M, Fu ZF, Zhao L
Veterinary microbiology 2022 Feb;265:109326
Veterinary microbiology 2022 Feb;265:109326
Cinnamic Aldehyde, the main monomer component of Cinnamon, exhibits anti-inflammatory property in OA synovial fibroblasts via TLR4/MyD88 pathway.
Chen P, Zhou J, Ruan A, Zeng L, Liu J, Wang Q
Journal of cellular and molecular medicine 2022 Feb;26(3):913-924
Journal of cellular and molecular medicine 2022 Feb;26(3):913-924
Cancer-cell-derived GABA promotes β-catenin-mediated tumour growth and immunosuppression.
Huang D, Wang Y, Thompson JW, Yin T, Alexander PB, Qin D, Mudgal P, Wu H, Liang Y, Tan L, Pan C, Yuan L, Wan Y, Li QJ, Wang XF
Nature cell biology 2022 Feb;24(2):230-241
Nature cell biology 2022 Feb;24(2):230-241
The volume-regulated anion channel LRRC8C suppresses T cell function by regulating cyclic dinucleotide transport and STING-p53 signaling.
Concepcion AR, Wagner LE 2nd, Zhu J, Tao AY, Yang J, Khodadadi-Jamayran A, Wang YH, Liu M, Rose RE, Jones DR, Coetzee WA, Yule DI, Feske S
Nature immunology 2022 Feb;23(2):287-302
Nature immunology 2022 Feb;23(2):287-302
Mesenchymal stem cell-derived exosome mediated long non-coding RNA KLF3-AS1 represses autophagy and apoptosis of chondrocytes in osteoarthritis.
Wen C, Lin L, Zou R, Lin F, Liu Y
Cell cycle (Georgetown, Tex.) 2022 Feb;21(3):289-303
Cell cycle (Georgetown, Tex.) 2022 Feb;21(3):289-303
Role of TGF-β1 in Fluoride-Treated Osteoblasts at Different Stages.
Jiang N, Xu W, Zhang Z, Jin H, Yang Y, Zhang J, Xu H
Biological trace element research 2022 Feb;200(2):740-748
Biological trace element research 2022 Feb;200(2):740-748
Zinc Protects against Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in TM3 Leydig Cells.
Xiong Y, Li J, He S
Biological trace element research 2022 Feb;200(2):728-739
Biological trace element research 2022 Feb;200(2):728-739
Assessing Mitochondrial DNA Release into the Cytosol and Subsequent Activation of Innate Immune-related Pathways in Mammalian Cells.
Bryant JD, Lei Y, VanPortfliet JJ, Winters AD, West AP
Current protocols 2022 Feb;2(2):e372
Current protocols 2022 Feb;2(2):e372
Survivin suppression heightens BZML-induced mitotic catastrophe to overcome multidrug resistance by removing therapy-induced senescent A549/Taxol cells.
Bai Z, Zhou Y, Ye X, Li Y, Peng Y, Guan Q, Zhang W, Ma L
Biochimica et biophysica acta. Molecular cell research 2022 Feb;1869(2):119174
Biochimica et biophysica acta. Molecular cell research 2022 Feb;1869(2):119174
MxB inhibits long interspersed element type 1 retrotransposition.
Huang Y, Xu F, Mei S, Liu X, Zhao F, Wei L, Fan Z, Hu Y, Wang L, Ai B, Cen S, Liang C, Guo F
PLoS genetics 2022 Feb;18(2):e1010034
PLoS genetics 2022 Feb;18(2):e1010034
miRNA-338-3p inhibits glioma cell proliferation and progression by targeting MYT1L.
Yu Z, Liu Y, Li Y, Zhang J, Peng J, Gong J, Xia Y, Wang L
Brain research bulletin 2022 Feb;179:1-12
Brain research bulletin 2022 Feb;179:1-12
The histone deacetylase inhibitor belinostat ameliorates experimental autoimmune encephalomyelitis in mice by inhibiting TLR2/MyD88 and HDAC3/ NF-κB p65-mediated neuroinflammation.
Shen Y, Yang R, Zhao J, Chen M, Chen S, Ji B, Chen H, Liu D, Li L, Du G
Pharmacological research 2022 Feb;176:105969
Pharmacological research 2022 Feb;176:105969
Anti-Inflammatory and Anti-Oxidant Activity of Ultra-Short Wave Diathermy on LPS-Induced Rat Lung Injury.
Wu Q, Qu M, Zhong P, Zeng Y, Wang J, Zhang Q, Wang T, Liu D, Yang L, Zhou J, Wang T
Bulletin of experimental biology and medicine 2022 Feb;172(4):423-429
Bulletin of experimental biology and medicine 2022 Feb;172(4):423-429
OLFM4 depletion sensitizes gallbladder cancer cells to cisplatin through the ARL6IP1/caspase-3 axis.
Lin Z, Yang S, Zhou Y, Hou Z, Li L, Meng M, Ge C, Zeng B, Lai J, Gao H, Zhao Y, Xie Y, He S, Tang W, Li R, Tan J, Wang W
Translational oncology 2022 Feb;16:101331
Translational oncology 2022 Feb;16:101331
IL-22 Downregulates Peptidylarginine Deiminase-1 in Human Keratinocytes: Adding Another Piece to the IL-22 Puzzle in Epidermal Barrier Formation.
Padhi A, Srivastava A, Ramesh A, Ehrström M, Simon M, Sonkoly E, Eidsmo L, Bergman P, Lysell J
The Journal of investigative dermatology 2022 Feb;142(2):333-342.e6
The Journal of investigative dermatology 2022 Feb;142(2):333-342.e6
Sodium butyrate alleviates pre-eclampsia in pregnant rats by improving the gut microbiota and short-chain fatty acid metabolites production.
Yong W, Zhao Y, Jiang X, Li P
Journal of applied microbiology 2022 Feb;132(2):1370-1383
Journal of applied microbiology 2022 Feb;132(2):1370-1383
Pleckstrin homology-like domain family A, member 3, a miR-19a-3p-regulated gene, suppresses tumor growth in osteosarcoma by downregulating the Akt pathway.
Wang P, Huang Y, Xia X, Han J, Zhang L, Zhao W
Bioengineered 2022 Feb;13(2):3993-4009
Bioengineered 2022 Feb;13(2):3993-4009
Salvianolic acid B alleviates diabetic endothelial and mitochondrial dysfunction by down-regulating apoptosis and mitophagy of endothelial cells.
Xiang J, Zhang C, Di T, Chen L, Zhao W, Wei L, Zhou S, Wu X, Wang G, Zhang Y
Bioengineered 2022 Feb;13(2):3486-3502
Bioengineered 2022 Feb;13(2):3486-3502
Vibrio harveyi infections induce production of proinflammatory cytokines in murine peritoneal macrophages via activation of p38 MAPK and NF-κB pathways, but reversed by PI3K/AKT pathways.
Yu G, Yu H, Yang Q, Wang J, Fan H, Liu G, Wang L, Bello BK, Zhao P, Zhang H, Dong J
Developmental and comparative immunology 2022 Feb;127:104292
Developmental and comparative immunology 2022 Feb;127:104292
Persistent high glucose induced EPB41L4A-AS1 inhibits glucose uptake via GCN5 mediating crotonylation and acetylation of histones and non-histones.
Liao W, Xu N, Zhang H, Liao W, Wang Y, Wang S, Zhang S, Jiang Y, Xie W, Zhang Y
Clinical and translational medicine 2022 Feb;12(2):e699
Clinical and translational medicine 2022 Feb;12(2):e699
Paclitaxel-based supramolecular hydrogel loaded with mifepristone for the inhibition of breast cancer metastasis.
Zhao CC, Zhang CG, Sun X, Guo Q, Liu J, Liu Y, Hao YN, Feng G, Yang L, Liu H, Liu J
Cancer science 2022 Feb;113(2):733-743
Cancer science 2022 Feb;113(2):733-743
One-Step Synthesis of Multifunctional Chitosan Hydrogel for Full-Thickness Wound Closure and Healing.
Guo S, Yao M, Zhang D, He Y, Chang R, Ren Y, Guan F
Advanced healthcare materials 2022 Feb;11(4):e2101808
Advanced healthcare materials 2022 Feb;11(4):e2101808
Sodium houttuynia alleviates airway inflammation in asthmatic mice by regulating FoxP3/RORγT expression and reversing Treg/Th17 cell imbalance.
Wang C, Huang CF, Li M
International immunopharmacology 2022 Feb;103:108487
International immunopharmacology 2022 Feb;103:108487
MiR-29b-1-5p regulates the proliferation and differentiation of chicken primary myoblasts and analysis of its effective targets.
Li Y, Zhai B, Yuan P, Fan S, Jin W, Li W, Sun G, Tian Y, Liu X, Kang X, Li G
Poultry science 2022 Feb;101(2):101557
Poultry science 2022 Feb;101(2):101557
ATF6-Mediated Unfolded Protein Response Facilitates Adeno-associated Virus 2 (AAV2) Transduction by Releasing the Suppression of the AAV Receptor on Endoplasmic Reticulum Stress.
Cui M, Zhao Q, Wang J, Si Y, Cheng S, Ding W
Journal of virology 2022 Feb 9;96(3):e0110321
Journal of virology 2022 Feb 9;96(3):e0110321
The spliceosome component Usp39 controls B cell development by regulating immunoglobulin gene rearrangement.
Ruan GX, Li Y, Chen W, Huang H, Zhang R, Chen C, Lam KP, Xu S, Ou X
Cell reports 2022 Feb 8;38(6):110338
Cell reports 2022 Feb 8;38(6):110338
Staphylococcus aureus mediates pyroptosis in bovine mammary epithelial cell via activation of NLRP3 inflammasome.
Wang X, Liu M, Geng N, Du Y, Li Z, Gao X, Han B, Liu J, Liu Y
Veterinary research 2022 Feb 5;53(1):10
Veterinary research 2022 Feb 5;53(1):10
AQP4 Attenuated TRAF6/NFκB Activation in Acrylamide-Induced Neurotoxicity.
Hung CY, Chang CH, Lin TJ, Yi HH, Tsai NZ, Chen YR, Chen YT
Molecules (Basel, Switzerland) 2022 Feb 4;27(3)
Molecules (Basel, Switzerland) 2022 Feb 4;27(3)
Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance.
Chen Y, Wu X, Zhang J, Pan G, Wang X, Guo X, Wang J, Cui X, Gao H, Cheng M, Yang J, Zhang C, Jiang F
EMBO reports 2022 Feb 3;23(3):e53373
EMBO reports 2022 Feb 3;23(3):e53373
Heterozygous FMN2 missense variant found in a family case of premature ovarian insufficiency.
Li J, Peng T, Wang L, Long P, Quan R, Tan H, Zeng M, Wu X, Yang J, Xiao H, Shi X
Journal of ovarian research 2022 Feb 28;15(1):31
Journal of ovarian research 2022 Feb 28;15(1):31
MYSM1 induces apoptosis and sensitizes TNBC cells to cisplatin via RSK3-phospho-BAD pathway.
Guan X, Meng X, Zhu K, Kai J, Liu Y, Ma Q, Tong Y, Zheng H, Xie S, Ma X, Wang Y, Lu R, Guo L
Cell death discovery 2022 Feb 26;8(1):84
Cell death discovery 2022 Feb 26;8(1):84
Changes of flavin-containing monooxygenases and trimethylamine-N-oxide may be involved in the promotion of non-alcoholic fatty liver disease by intestinal microbiota metabolite trimethylamine.
Shi C, Pei M, Wang Y, Chen Q, Cao P, Zhang L, Guo J, Deng W, Wang L, Li X, Gong Z
Biochemical and biophysical research communications 2022 Feb 26;594:1-7
Biochemical and biophysical research communications 2022 Feb 26;594:1-7
Norepinephrine promotes glioma cell migration through up-regulating the expression of Twist1.
Wang X, Wang Y, Xie F, Song ZT, Zhang ZQ, Zhao Y, Wang SD, Hu H, Zhang YS, Qian LJ
BMC cancer 2022 Feb 26;22(1):213
BMC cancer 2022 Feb 26;22(1):213
Circular RNA circSHPRH inhibits the malignant behaviors of bladder cancer by regulating the miR-942/BARX2 pathway.
Zuo L, Zhu Y, Han J, Liu H
Aging 2022 Feb 24;14(4):1891-1909
Aging 2022 Feb 24;14(4):1891-1909
Comprehensive Analysis of Protein Acetylation and Glucose Metabolism in Mouse Brains Infected with Rabies Virus.
Pei J, Yuan Y, Tian D, Huang F, Zhang C, Wang C, Zhou M, Chen H, Fu Z, Zhao L
Journal of virology 2022 Feb 23;96(4):e0194221
Journal of virology 2022 Feb 23;96(4):e0194221
Neuroprotection of chicoric acid in a mouse model of Parkinson's disease involves gut microbiota and TLR4 signaling pathway.
Wang N, Feng BN, Hu B, Cheng YL, Guo YH, Qian H
Food & function 2022 Feb 21;13(4):2019-2032
Food & function 2022 Feb 21;13(4):2019-2032
Employing CRISPR-Cas9 to Generate CD133 Synthetic Lethal Melanoma Stem Cells.
Simbulan-Rosenthal CM, Haribabu Y, Vakili S, Kuo LW, Clark H, Dougherty R, Alobaidi R, Carney B, Sykora P, Rosenthal DS
International journal of molecular sciences 2022 Feb 20;23(4)
International journal of molecular sciences 2022 Feb 20;23(4)
The deubiquitinating enzyme USP20 regulates the stability of the MCL1 protein.
Feng J, Liu P, Li X, Zhang D, Lin H, Hou Z, Guo C, Niu Y, Dai B, Wang O, Qi M, Wang H, Zhou H
Biochemical and biophysical research communications 2022 Feb 19;593:122-128
Biochemical and biophysical research communications 2022 Feb 19;593:122-128
PINK1-parkin-mediated neuronal mitophagy deficiency in prion disease.
Li J, Lai M, Zhang X, Li Z, Yang D, Zhao M, Wang D, Sun Z, Ehsan S, Li W, Gao H, Zhao D, Yang L
Cell death & disease 2022 Feb 18;13(2):162
Cell death & disease 2022 Feb 18;13(2):162
Overexpressed mitogen-and stress-activated protein kinase 1 promotes the resistance of cytarabine in acute myeloid leukemia through brahma related gene 1-mediated upregulation of heme oxygenase-1.
Zhang S, Pan C, Shang Q, Wang W, Hu T, Liu P, Chen S, Wang J, Fang Q
European journal of pharmacology 2022 Feb 15;917:174722
European journal of pharmacology 2022 Feb 15;917:174722
Synthesis and biological evaluation of aminobenzamides containing purine moiety as class I histone deacetylases inhibitors.
Mao PT, He WB, Mai X, Feng LH, Li N, Liao YJ, Zhu CS, Li J, Chen T, Liu SH, Zhang QM, He L
Bioorganic & medicinal chemistry 2022 Feb 15;56:116599
Bioorganic & medicinal chemistry 2022 Feb 15;56:116599
Asprosin induces vascular endothelial-to-mesenchymal transition in diabetic lower extremity peripheral artery disease.
You M, Liu Y, Wang B, Li L, Zhang H, He H, Zhou Q, Cao T, Wang L, Zhao Z, Zhu Z, Gao P, Yan Z
Cardiovascular diabetology 2022 Feb 15;21(1):25
Cardiovascular diabetology 2022 Feb 15;21(1):25
Themis is indispensable for IL-2 and IL-15 signaling in T cells.
Liu Y, Cong Y, Niu Y, Yuan Y, Tan F, Lai Q, Hu Y, Hou B, Li J, Lin C, Zheng H, Dong J, Tang J, Chen Q, Brzostek J, Zhang X, Chen XL, Wang HR, Gascoigne NRJ, Xu B, Lin SH, Fu G
Science signaling 2022 Feb 15;15(721):eabi9983
Science signaling 2022 Feb 15;15(721):eabi9983
Novel stress granule-like structures are induced via a paracrine mechanism during viral infection.
Iadevaia V, Burke JM, Eke L, Moller-Levet C, Parker R, Locker N
Journal of cell science 2022 Feb 15;135(4)
Journal of cell science 2022 Feb 15;135(4)
Programmed death-ligand 1 signaling and expression are reversible by lycopene via PI3K/AKT and Raf/MEK/ERK pathways in tongue squamous cell carcinoma.
Peng M, Fan S, Li J, Zhou X, Liao Q, Tang F, Liu W
Genes & nutrition 2022 Feb 14;17(1):3
Genes & nutrition 2022 Feb 14;17(1):3
Chicoric Acid Prevents Neuroinflammation and Neurodegeneration in a Mouse Parkinson's Disease Model: Immune Response and Transcriptome Profile of the Spleen and Colon.
Wang N, Li R, Feng B, Cheng Y, Guo Y, Qian H
International journal of molecular sciences 2022 Feb 12;23(4)
International journal of molecular sciences 2022 Feb 12;23(4)
ZHX2 inhibits thyroid cancer metastasis through transcriptional inhibition of S100A14.
Zhang Y, Sun M, Gao L, Liang X, Ma C, Lu J, Yue X
Cancer cell international 2022 Feb 12;22(1):76
Cancer cell international 2022 Feb 12;22(1):76
A Second Near-Infrared Ru(II) Polypyridyl Complex for Synergistic Chemo-Photothermal Therapy.
Liu Y, Li Q, Gu M, Lu D, Xiong X, Zhang Z, Pan Y, Liao Y, Ding Q, Gong W, Chen DS, Guan M, Wu J, Tian Z, Deng H, Gu L, Hong X, Xiao Y
Journal of medicinal chemistry 2022 Feb 10;65(3):2225-2237
Journal of medicinal chemistry 2022 Feb 10;65(3):2225-2237
Structural Optimization and Structure-Activity Relationship Studies of 6,6-Dimethyl-4-(phenylamino)-6H-pyrimido[5,4-b][1,4]oxazin-7(8H)-one Derivatives as A New Class of Potent Inhibitors of Pan-Trk and Their Drug-Resistant Mutants.
Pan S, Zhang L, Luo X, Nan J, Yang W, Bin H, Li Y, Huang Q, Wang T, Pan Z, Mu B, Wang F, Tian C, Liu Y, Li L, Yang S
Journal of medicinal chemistry 2022 Feb 10;65(3):2035-2058
Journal of medicinal chemistry 2022 Feb 10;65(3):2035-2058
Discovery of 3,4-Dihydrobenzo[f][1,4]oxazepin-5(2H)-one Derivatives as a New Class of Selective TNIK Inhibitors and Evaluation of Their Anti-Colorectal Cancer Effects.
Li Y, Zhang L, Yang R, Qiao Z, Wu M, Huang C, Tian C, Luo X, Yang W, Zhang Y, Li L, Yang S
Journal of medicinal chemistry 2022 Feb 10;65(3):1786-1807
Journal of medicinal chemistry 2022 Feb 10;65(3):1786-1807
Anti-proliferation and anti-inflammation effects of corilagin in rheumatoid arthritis by downregulating NF-κB and MAPK signaling pathways.
Shen Y, Teng L, Qu Y, Liu J, Zhu X, Chen S, Yang L, Huang Y, Song Q, Fu Q
Journal of ethnopharmacology 2022 Feb 10;284:114791
Journal of ethnopharmacology 2022 Feb 10;284:114791
Physiological and transcriptomic analyses reveal the toxicological mechanism and risk assessment of environmentally-relevant waterborne tetracycline exposure on the gills of tilapia (Oreochromis niloticus).
Xu YC, Liu GH, Xu YH, Zhao T, Zheng H, Tan XY
The Science of the total environment 2022 Feb 1;806(Pt 3):151290
The Science of the total environment 2022 Feb 1;806(Pt 3):151290
Berberine inhibits gastric cancer development and progression by regulating the JAK2/STAT3 pathway and downregulating IL-6.
Xu M, Ren L, Fan J, Huang L, Zhou L, Li X, Ye X
Life sciences 2022 Feb 1;290:120266
Life sciences 2022 Feb 1;290:120266
Silk fibroin nanofibrous scaffolds incorporated with microRNA-222 loaded chitosan nanoparticles for enhanced neuronal differentiation of neural stem cells.
Li Z, Meng Z, Zhao Z
Carbohydrate polymers 2022 Feb 1;277:118791
Carbohydrate polymers 2022 Feb 1;277:118791
Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis.
Xu S, Yang X, Chen Q, Liu Z, Chen Y, Yao X, Xiao A, Tian J, Xie L, Zhou M, Hu Z, Zhu F, Xu X, Hou F, Nie J
EBioMedicine 2022 Dec;86:104312
EBioMedicine 2022 Dec;86:104312
PRSS2 overexpression relates to poor prognosis and promotes proliferation, migration and invasion in gastric cancer.
Chen Y, Wang B, Zhao Z, Li M, Wang F
Tissue & cell 2022 Dec;79:101949
Tissue & cell 2022 Dec;79:101949
Integrated bioinformatics analysis and screening of hub genes in polycystic ovary syndrome.
Qiao G, Xing J, Luo X, Zhang C, Yi J
Endocrine 2022 Dec;78(3):615-627
Endocrine 2022 Dec;78(3):615-627
CircCERS6 Suppresses the Development of Epithelial Ovarian Cancer Through Mediating miR-630/RASSF8.
Li X, Jiang X, Lu J, Lin Y, Jiang L, Li Y, Wan F, Wang C
Biochemical genetics 2022 Dec;60(6):2611-2629
Biochemical genetics 2022 Dec;60(6):2611-2629
Yiqi Huoxue Tongluo recipe regulates NR4A1 to improve renal mitochondrial function in unilateral ureteral obstruction (UUO) rats.
He Z, Zhang M, Xu H, Zhou W, Xu C, Wang Z, He M, Wang X
Pharmaceutical biology 2022 Dec;60(1):2308-2318
Pharmaceutical biology 2022 Dec;60(1):2308-2318
Catalpol relieved angiotensin II-induced blood-brain barrier destruction via inhibiting the TLR4 pathway in brain endothelial cells.
Xia Y, Lu YW, Hao RJ, Yu GR
Pharmaceutical biology 2022 Dec;60(1):2210-2218
Pharmaceutical biology 2022 Dec;60(1):2210-2218
Aspirin relieves the calcification of aortic smooth muscle cells by enhancing the heat shock response.
Shen Q, Chen Q, Liu Y, Xue X, Shen X, He Q, Wang G, Han F
Pharmaceutical biology 2022 Dec;60(1):17-24
Pharmaceutical biology 2022 Dec;60(1):17-24
Study on the biological mechanism of urolithin a on nasopharyngeal carcinoma in vitro.
Yang Y, Ren ZZ, Wei WJ, He ZL, Deng YL, Wang Z, Fan YC, Zhou J, Jiang LH
Pharmaceutical biology 2022 Dec;60(1):1566-1577
Pharmaceutical biology 2022 Dec;60(1):1566-1577
Louki Zupa decoction attenuates the airway inflammation in acute asthma mice induced by ovalbumin through IL-33/ST2-NF-κB/GSK3β/mTOR signalling pathway.
Huang X, Yu H, Xie C, Zhou YL, Chen MM, Shi HL, Tang WF, Dong JC, Luo QL
Pharmaceutical biology 2022 Dec;60(1):1520-1532
Pharmaceutical biology 2022 Dec;60(1):1520-1532
Structure and biological evaluation of Caenorhabditis elegans CISD-1/mitoNEET, a KLP-17 tail domain homologue, supports attenuation of paraquat-induced oxidative stress through a p38 MAPK-mediated antioxidant defense response.
Boos JR, Jandrain HN, Hagiuda E, Taguchi AT, Hasegawa K, Fedun BL, Taylor SJ, Elad SM, Faber SE, Kumasaka T, Iwasaki T, Geldenhuys WJ
Advances in redox research 2022 Dec;6
Advances in redox research 2022 Dec;6
FUS Mutation Causes Disordered Lipid Metabolism in Skeletal Muscle Associated with ALS.
Zhou B, Zheng Y, Li X, Dong H, Yu J, Zou Y, Zhu M, Yu Y, Fang X, Zhou M, Zhang W, Yuan Y, Wang Z, Deng J, Hong D
Molecular neurobiology 2022 Dec;59(12):7265-7277
Molecular neurobiology 2022 Dec;59(12):7265-7277
circSKIL promotes osteoblastic differentiation of periodontal ligament cells by sponging miR-532-5p to activate Notch signaling.
Zhong X, Wang H
Journal of periodontal research 2022 Dec;57(6):1148-1158
Journal of periodontal research 2022 Dec;57(6):1148-1158
Knockdown of ZBTB11 impedes R-loop elimination and increases the sensitivity to cisplatin by inhibiting DDX1 transcription in bladder cancer.
Chen L, Liu Z, Tang H, Zhou Z, Chen J, Ma Z, Deng M, Li X, Wu Y, Zheng L, Zhou L, Zheng X, Liu Z
Cell proliferation 2022 Dec;55(12):e13325
Cell proliferation 2022 Dec;55(12):e13325
Periostin contributes to the adventitial remodeling of atherosclerosis by activating adventitial fibroblasts.
Wang Z, Li G, Li M, Hu L, Hao Z, Li Q, Sun C
Atherosclerosis plus 2022 Dec;50:57-64
Atherosclerosis plus 2022 Dec;50:57-64
Dissection of cellular and molecular mechanisms of aristolochic acid-induced hepatotoxicity via single-cell transcriptomics.
Luo P, Chen J, Zhang Q, Xia F, Wang C, Bai Y, Tang H, Liu D, Gu L, Du Q, Xiao W, Yang C, Wang J
Precision clinical medicine 2022 Dec;5(4):pbac023
Precision clinical medicine 2022 Dec;5(4):pbac023
PEDF inhibits non‑small cell lung cancer proliferation by suppressing autophagy through downregulation of AMPK‑ULK1 signaling.
Miao H, Hui H, Li H, Lin Y, Li D, Luo M, Jiang B, Zhang Y
Oncology reports 2022 Dec;48(6)
Oncology reports 2022 Dec;48(6)
The LINC00152/miR-205-5p/CXCL11 axis in hepatocellular carcinoma cancer-associated fibroblasts affects cancer cell phenotypes and tumor growth.
Liu G, Yang ZF, Sun J, Sun BY, Zhou PY, Zhou C, Guan RY, Wang ZT, Yi Y, Qiu SJ
Cellular oncology (Dordrecht, Netherlands) 2022 Dec;45(6):1435-1449
Cellular oncology (Dordrecht, Netherlands) 2022 Dec;45(6):1435-1449
DNASE1L3 inhibits hepatocellular carcinoma by delaying cell cycle progression through CDK2.
Sun J, Wang X, Shen Q, Wang M, Chen S, Zhang X, Huang Y, Zhang Z, Li W, Yuan Y, Huang Z
Cellular oncology (Dordrecht, Netherlands) 2022 Dec;45(6):1187-1202
Cellular oncology (Dordrecht, Netherlands) 2022 Dec;45(6):1187-1202
CircRNA-001241 mediates sorafenib resistance of hepatocellular carcinoma cells by sponging miR-21-5p and regulating TIMP3 expression.
Yang Q, Wu G
Gastroenterologia y hepatologia 2022 Dec;45(10):742-752
Gastroenterologia y hepatologia 2022 Dec;45(10):742-752
Yanghe decoction attenuated pain hypersensitivity induced by michigan cancer foundation-7 injection in rats with bone metastases from breast cancer by inhibiting transient receptor potential ankyrin 1.
Hui G, Yang LI, Lei F, Yujie X, Lizhong H, Dan M, Hui Z
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Dec;42(6):948-955
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Dec;42(6):948-955
A homogalacturonan from Lonicera japonica Thunb. disrupts angiogenesis via epidermal growth factor receptor and Delta-like 4 associated signaling.
Liao W, Hu X, Du Z, Wang P, Ding K
Glycoconjugate journal 2022 Dec;39(6):725-735
Glycoconjugate journal 2022 Dec;39(6):725-735
Photobiomodulation effects in metalloproteinases expression in zymosan-induced arthritis.
Dos Anjos LMJ, Quirino-Teixeira AC, Hottz ED, da Fonseca AS, Gameiro J, de Paoli F
Lasers in medical science 2022 Dec;37(9):3661-3670
Lasers in medical science 2022 Dec;37(9):3661-3670
3-Arylcoumarin inhibits vascular calcification by inhibiting the generation of AGEs and anti-oxidative stress.
Li Y, Pan Y, Wang L, Wang X, Chu H, Li Y, Mu Y, Sun J
Journal of enzyme inhibition and medicinal chemistry 2022 Dec;37(1):2147-2157
Journal of enzyme inhibition and medicinal chemistry 2022 Dec;37(1):2147-2157
Effects of bicyclol on hepatic sinusoidal obstruction syndrome induced by Gynura segetum.
Yao J, Wu J, Jia S, Shao J, Zhang X, Xu Z, Zhang H, Li H, Yao X
Journal of clinical laboratory analysis 2022 Dec;36(12):e24793
Journal of clinical laboratory analysis 2022 Dec;36(12):e24793
Flavonoid extract of saffron by-product alleviates hyperuricemia via inhibiting xanthine oxidase and modulating gut microbiota.
Chen N, Wang R, Li H, Wang W, Wang L, Yin X, Yao R, Yang B
Phytotherapy research : PTR 2022 Dec;36(12):4604-4619
Phytotherapy research : PTR 2022 Dec;36(12):4604-4619
Andrographolide suppresses breast cancer progression by modulating tumor-associated macrophage polarization through the Wnt/β-catenin pathway.
Li L, Yang LL, Yang SL, Wang RQ, Gao H, Lin ZY, Zhao YY, Tang WW, Han R, Wang WJ, Liu P, Hou ZL, Meng MY, Liao LW
Phytotherapy research : PTR 2022 Dec;36(12):4587-4603
Phytotherapy research : PTR 2022 Dec;36(12):4587-4603
Expression and significance of let-7a and tumor necrosis factor-alpha in placenta of severe preeclampsia.
Zhou T, Wang W, Qi T, Ma S, Lu W
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022 Dec;35(25):7363-7367
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022 Dec;35(25):7363-7367
Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia.
Hu CL, Chen BY, Li Z, Yang T, Xu CH, Yang R, Yu PC, Zhao J, Liu T, Liu N, Shan B, Zhang Q, Song J, Fei MY, Zong LJ, Zhang JY, Wu JC, Chen SB, Wang Y, Chang B, Hou D, Liu P, Jiang Y, Li X, Chen X, Deng CH, Ren YY, Wang R, Jin J, Xue K, Zhang Y, Du M, Shi J, Wu LY, Chang CK, Shen S, Chen Z, Chen SJ, Liu X, Sun XJ, Zheng M, Wang L
Cell research 2022 Dec;32(12):1105-1123
Cell research 2022 Dec;32(12):1105-1123
Androgen receptor suppresses β-adrenoceptor-mediated CREB activation and thermogenesis in brown adipose tissue of male mice.
Harada N, Kubo K, Onishi T, Kitakaze T, Goto T, Inui H, Yamaji R
The Journal of biological chemistry 2022 Dec;298(12):102619
The Journal of biological chemistry 2022 Dec;298(12):102619
A recombinant scFv antibody-based fusion protein that targets EGFR associated with IMPDH2 downregulation and its drug conjugate show therapeutic efficacy against esophageal cancer.
He S, Zhao C, Tao H, Sheng W, Gao R, Liu X, Zhen Y
Drug delivery 2022 Dec;29(1):1243-1256
Drug delivery 2022 Dec;29(1):1243-1256
HIV-1 Tat drives the Fabp4/NF-κB feedback loop in microglia to mediate inflammatory response and neuronal apoptosis.
Zhou X, Zhou S, Tao J, Gao Y, Meng G, Cao D, Gao L
Journal of neurovirology 2022 Dec;28(4-6):483-496
Journal of neurovirology 2022 Dec;28(4-6):483-496
Enhancement of astrocytic gap junctions Connexin43 coupling can improve long-term isoflurane anesthesia-mediated brain network abnormalities and cognitive impairment.
Dong R, Lv P, Han Y, Jiang L, Wang Z, Peng L, Ma Z, Xia T, Zhang B, Gu X
CNS neuroscience & therapeutics 2022 Dec;28(12):2281-2297
CNS neuroscience & therapeutics 2022 Dec;28(12):2281-2297
KDM6B cooperates with Tau and regulates synaptic plasticity and cognition via inducing VGLUT1/2.
Wang Y, Khandelwal N, Liu S, Zhou M, Bao L, Wang JE, Kumar A, Xing C, Gibson JR, Wang Y
Molecular psychiatry 2022 Dec;27(12):5213-5226
Molecular psychiatry 2022 Dec;27(12):5213-5226
c-Myc plays a critical role in the antileukemic activity of the Mcl-1-selective inhibitor AZD5991 in acute myeloid leukemia.
Liu S, Qiao X, Wu S, Gai Y, Su Y, Edwards H, Wang Y, Lin H, Taub JW, Wang G, Ge Y
Apoptosis : an international journal on programmed cell death 2022 Dec;27(11-12):913-928
Apoptosis : an international journal on programmed cell death 2022 Dec;27(11-12):913-928
FBXL6 depletion restrains clear cell renal cell carcinoma progression.
Yu Y, Yao W, Wang T, Xue W, Meng Y, Cai L, Jian W, Yu Y, Zhang C
Translational oncology 2022 Dec;26:101550
Translational oncology 2022 Dec;26:101550
Hsp90 Inhibitor STA9090 induced VPS35 related extracellular vesicle release and metastasis in hepatocellular carcinoma.
Tan W, Zhang J, Liu L, Liang M, Li J, Deng Z, Zheng Z, Deng Y, Liu C, Li Y, Xie G, Zhang J, Zou F, Chen X
Translational oncology 2022 Dec;26:101502
Translational oncology 2022 Dec;26:101502
miR‑141 impairs mitochondrial function in cardiomyocytes subjected to hypoxia/reoxygenation by targeting Sirt1 and MFN2.
Zhang H, Wang Y, Wu K, Liu R, Wang H, Yao Y, Kvietys P, Rui T
Experimental and therapeutic medicine 2022 Dec;24(6):763
Experimental and therapeutic medicine 2022 Dec;24(6):763
Network pharmacology and molecular docking analysis on molecular targets and mechanisms of Gastrodia elata Blume in the treatment of ischemic stroke.
Luo Y, Chen P, Yang L, Duan X
Experimental and therapeutic medicine 2022 Dec;24(6):742
Experimental and therapeutic medicine 2022 Dec;24(6):742
Pseudogene CSPG4P12 affects the biological behavior of non‑small cell lung cancer by Bcl‑2/Bax mitochondrial apoptosis pathway.
Hu W, Wu H, Li A, Zheng X, Zhang W, Tian Q, Zhang X
Experimental and therapeutic medicine 2022 Dec;24(6):734
Experimental and therapeutic medicine 2022 Dec;24(6):734
NSUN5 promotes progression and predicts poor prognosis in hepatocellular carcinoma.
Zhang XW, Wu LY, Liu HR, Huang Y, Qi Q, Zhong R, Zhu L, Gao CF, Zhou L, Yu J, Wu HG
Oncology letters 2022 Dec;24(6):439
Oncology letters 2022 Dec;24(6):439
The Mechano-Ubiquitinome of Articular Cartilage: Differential Ubiquitination and Activation of a Group of ER-Associated DUBs and ER Stress Regulators.
Kaokhum N, Pinto-Fernández A, Wilkinson M, Kessler BM, Ismail HM
Molecular & cellular proteomics : MCP 2022 Dec;21(12):100419
Molecular & cellular proteomics : MCP 2022 Dec;21(12):100419
Efficient reprogramming of human fibroblasts using RNA reprogramming with DAPT and iDOT1L under normoxia conditions.
Morita K, Nakamura A, Machida M, Kawasaki T, Nakanishi R, Ichida J, Iwata T, Umezawa A, Akutsu H
Regenerative therapy 2022 Dec;21:389-397
Regenerative therapy 2022 Dec;21:389-397
Polydopamine-mediated graphene oxide and nanohydroxyapatite-incorporated conductive scaffold with an immunomodulatory ability accelerates periodontal bone regeneration in diabetes.
Li Y, Yang L, Hou Y, Zhang Z, Chen M, Wang M, Liu J, Wang J, Zhao Z, Xie C, Lu X
Bioactive materials 2022 Dec;18:213-227
Bioactive materials 2022 Dec;18:213-227
Сyclooxygenase-2 Inhibitor Parecoxib Reduces LPS-Induced Activation of BV2 Microglia Cells.
Li X, Zhou JX, Qu YD, Kuang X
Bulletin of experimental biology and medicine 2022 Dec;174(2):210-215
Bulletin of experimental biology and medicine 2022 Dec;174(2):210-215
Oxidative phosphorylation regulates interleukin-10 production in regulatory B cells via the extracellular signal-related kinase pathway.
Zhu Y, Zhang X, Xie S, Bao W, Chen J, Wu Q, Lai X, Liu L, Xiong S, Peng Y
Immunology 2022 Dec;167(4):576-589
Immunology 2022 Dec;167(4):576-589
Rifaximin protects against circadian rhythm disruption-induced cognitive impairment through preventing gut barrier damage and neuroinflammation.
Meng D, Yang M, Hu L, Liu T, Zhang H, Sun X, Wang X, Chen Y, Jin Y, Liu R
Journal of neurochemistry 2022 Dec;163(5):406-418
Journal of neurochemistry 2022 Dec;163(5):406-418
Targeted lipidomics analysis of lysine 179 acetylation of ACSF2 in rat hepatic stellate cells.
Wang M, Su Y, Hou C, Ren K, Liu X, Zhao S, Wang Y, Liu X
Prostaglandins & other lipid mediators 2022 Dec;163:106671
Prostaglandins & other lipid mediators 2022 Dec;163:106671
Clitoria ternatea blue petal extract protects against obesity, oxidative stress, and inflammation induced by a high-fat, high-fructose diet in C57BL/6 mice.
Wang Y, Liu T, Xie Y, Li N, Liu Y, Wen J, Zhang M, Feng W, Huang J, Guo Y, Kabbas Junior T, Wang D, Granato D
Food research international (Ottawa, Ont.) 2022 Dec;162(Pt A):112008
Food research international (Ottawa, Ont.) 2022 Dec;162(Pt A):112008
Facile discovery of red blood cell deformation and compromised membrane/skeleton assembly in Prader-Willi syndrome.
Yang Y, Li G, Wang Y, Sun Y, Xu C, Wei Z, Zhang S, Gao L, Liu S, Zhao J
Frontiers of medicine 2022 Dec;16(6):946-956
Frontiers of medicine 2022 Dec;16(6):946-956
R158Q and G212S, novel pathogenic compound heterozygous variants in SLC12A3 of Gitelman syndrome.
Li Z, Wu H, Wei S, Liu M, Shi Y, Li M, Wang N, Fang L, Xiang B, Gao L, Xu C, Zhao J
Frontiers of medicine 2022 Dec;16(6):932-945
Frontiers of medicine 2022 Dec;16(6):932-945
Hyaluronic acids mediate the infiltration, migration, and M2 polarization of macrophages: evaluating metabolic molecular phenotypes in gliomas.
Zhang H, Zhang N, Dai Z, Wang Z, Zhang X, Liang X, Zhang L, Feng S, Wu W, Ye W, Zhang J, Luo P, Liu Z, Cheng Q, Liu Z
Molecular oncology 2022 Dec;16(22):3927-3948
Molecular oncology 2022 Dec;16(22):3927-3948
The transcription factor KLF14 attenuates LPS-induced acute lung injury by ameliorating apoptosis of alveolar epithelial cells in mice.
Liu L, Yuan Y, Zhou Y, Yao L, Li J, Chen F
Molecular immunology 2022 Dec;152:67-77
Molecular immunology 2022 Dec;152:67-77
The mechanism underlying ICAM-1 and E-selectin-mediated hypertriglyceridemic pancreatitis-associated lung injury.
Yu R, Hou C, Peng Y, Zhu X, Shi C, Huang D, Miao Y, Li Q
Molecular immunology 2022 Dec;152:55-66
Molecular immunology 2022 Dec;152:55-66
RPLP1, an NS4B-interacting protein, enhances production of CSFV through promoting translation of viral genome.
Zhang L, Lin J, Weng M, Wen Y, Zhang Y, Deng W
Virulence 2022 Dec;13(1):370-386
Virulence 2022 Dec;13(1):370-386
Regulation of host factor γ-H2AX level and location by enterovirus A71 for viral replication.
Yu J, Zhang W, Huo W, Meng X, Zhong T, Su Y, Liu Y, Liu J, Wang Z, Song F, Zhang S, Li Z, Yu X, Yu X, Hua S
Virulence 2022 Dec;13(1):241-257
Virulence 2022 Dec;13(1):241-257
Tetrandrine alleviates inflammation and neuron apoptosis in experimental traumatic brain injury by regulating the IRE1α/JNK/CHOP signal pathway.
Liu H, He S, Li C, Wang J, Zou Q, Liao Y, Chen R
Brain and behavior 2022 Dec;12(12):e2786
Brain and behavior 2022 Dec;12(12):e2786
Pathogenic variants in TSC2 might cause premature ovarian insufficiency through activated mTOR induced hyperactivation of primordial follicles.
Xu B, Li Z, Li S, Ke H, Zhang Q, Qin Y, Guo T
Fertility and sterility 2022 Dec;118(6):1139-1149
Fertility and sterility 2022 Dec;118(6):1139-1149
Di-2-ethylhexyl phthalate-induced miR-155-5p promoted lipid metabolism via inhibiting cAMP/PKA signaling pathway in human trophoblastic HTR-8/Svneo cells.
Gu X, Liu H, Luo W, Wang X, Wang H, Li L
Reproductive toxicology (Elmsford, N.Y.) 2022 Dec;114:22-31
Reproductive toxicology (Elmsford, N.Y.) 2022 Dec;114:22-31
Epoxymicheliolide prevents dextran sulfate sodium-induced colitis in mice by inhibiting TAK1-NF-κB pathway and activating Keap1-NRF2 signaling in macrophages.
He J, Liu L, Liu X, Chen H, Liu K, Huang N, Wang Y
International immunopharmacology 2022 Dec;113(Pt A):109404
International immunopharmacology 2022 Dec;113(Pt A):109404
Eplerenone inhibits the macrophage-to-myofibroblast transition in rats with UUO-induced type 4 cardiorenal syndrome through the MR/CTGF pathway.
Han Y, Xian Y, Gao X, Qiang P, Hao J, Yang F, Shimosawa T, Chang Y, Xu Q
International immunopharmacology 2022 Dec;113(Pt A):109396
International immunopharmacology 2022 Dec;113(Pt A):109396
Nodakenin attenuates cartilage degradation and inflammatory responses in a mice model of knee osteoarthritis by regulating mitochondrial Drp1/ROS/NLRP3 axis.
Yi N, Mi Y, Xu X, Li N, Chen B, Yan K, Tan K, Zhang B, Wang L, Kuang G, Lu M
International immunopharmacology 2022 Dec;113(Pt A):109349
International immunopharmacology 2022 Dec;113(Pt A):109349
Blockade of CBX4-mediated β-catenin SUMOylation attenuates airway epithelial barrier dysfunction in asthma.
Liang S, Zhou Z, Zhou Z, Liang J, Lin W, Zhang C, Zhou C, Zhao H, Meng X, Zou F, Yu C, Cai S
International immunopharmacology 2022 Dec;113(Pt A):109333
International immunopharmacology 2022 Dec;113(Pt A):109333
Brown adipocytes promote epithelial mesenchymal transition of neuroblastoma cells by inducing PPAR-γ/UCP2 expression.
Ge Z, Shang Y, Wang W, Yang J, Chen SZ
Adipocyte 2022 Dec;11(1):335-345
Adipocyte 2022 Dec;11(1):335-345
Isorhamnetin protects zearalenone-induced damage via the PI3K/Akt signaling pathway in porcine ovarian granulosa cells.
Li X, Chen H, Zhang Z, Duan J, Hua R, Li X, Yang L, Cheng J, Li Q
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Dec;11:381-390
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Dec;11:381-390
Systemic gene therapy for methylmalonic acidemia using the novel adeno-associated viral vector 44.9.
Chandler RJ, Di Pasquale G, Sloan JL, McCoy S, Hubbard BT, Kilts TM, Manoli I, Chiorini JA, Venditti CP
Molecular therapy. Methods & clinical development 2022 Dec 8;27:61-72
Molecular therapy. Methods & clinical development 2022 Dec 8;27:61-72
Melatonin Maintains Homeostasis and Potentiates the Anti-inflammatory Response in Staphylococcus aureus-Induced Mastitis through microRNA-16b/YAP1.
Chen Z, Wang K, Guo J, Zhou J, Loor JJ, Yang Z, Yang Y
Journal of agricultural and food chemistry 2022 Dec 7;70(48):15255-15270
Journal of agricultural and food chemistry 2022 Dec 7;70(48):15255-15270
GABA regulates IL-1β production in macrophages.
Fu J, Han Z, Wu Z, Xia Y, Yang G, Yin Y, Ren W
Cell reports 2022 Dec 6;41(10):111770
Cell reports 2022 Dec 6;41(10):111770
CIP2A deficiency promotes depression-like behaviors in mice through inhibition of dendritic arborization.
Hu WT, Liuyang ZY, Tian Y, Liang JW, Zhang XL, Zhang HL, Wang G, Huo Y, Shentu YP, Wang JZ, Wang XC, Lu YM, Westermarck J, Man HY, Liu R
EMBO reports 2022 Dec 6;23(12):e54911
EMBO reports 2022 Dec 6;23(12):e54911
Silencing of lncRNA SNHG17 inhibits the tumorigenesis of epithelial ovarian cancer through regulation of miR-485-5p/AKT1 axis.
Wang W, Yu S, Li W, Hu H, Zou G
Biochemical and biophysical research communications 2022 Dec 31;637:117-126
Biochemical and biophysical research communications 2022 Dec 31;637:117-126
LncRNA GAS5 regulates the Wnt/β-catenin pathway through the miR-18a-5p/AXIN2/GSK3β axis to inhibit the proliferation and migration of bladder cancer cells.
Zhang Z, Liu T, Cheng C, Wang J, Wang C, Huang H, Li Y
Carcinogenesis 2022 Dec 31;43(12):1176-1189
Carcinogenesis 2022 Dec 31;43(12):1176-1189
Mechanically activated ion channel Piezo1 contributes to melanoma malignant progression through AKT/mTOR signaling.
Zhang S, Cao S, Gong M, Zhang W, Zhang W, Zhu Z, Wu S, Yue Y, Qian W, Ma Q, Wang S, Wang Z
Cancer biology & therapy 2022 Dec 31;23(1):336-347
Cancer biology & therapy 2022 Dec 31;23(1):336-347
Exosome-transmitted S100A4 induces immunosuppression and non-small cell lung cancer development by activating STAT3.
Wu X, Zhang H, Jiang G, Peng M, Li C, Lu J, Jiang S, Yang X, Jiang Y
Clinical and experimental immunology 2022 Dec 31;210(3):309-320
Clinical and experimental immunology 2022 Dec 31;210(3):309-320
Quercetin ameliorates memory impairment by inhibiting abnormal microglial activation in a mouse model of paradoxical sleep deprivation.
Zhang Y, Xie Y, Cheng Z, Xi K, Huang X, Kuang F, Wang W, Liu T, Guo B, Wu S
Biochemical and biophysical research communications 2022 Dec 3;632:10-16
Biochemical and biophysical research communications 2022 Dec 3;632:10-16
Geraniol-Mediated Suppression of Endoplasmic Reticulum Stress Protects against Cerebral Ischemia-Reperfusion Injury via the PERK-ATF4-CHOP Pathway.
Wu Y, Fan X, Chen S, Deng L, Jiang L, Yang S, Dong Z
International journal of molecular sciences 2022 Dec 29;24(1)
International journal of molecular sciences 2022 Dec 29;24(1)
SMYD3 associates with the NuRD (MTA1/2) complex to regulate transcription and promote proliferation and invasiveness in hepatocellular carcinoma cells.
Yang Y, Qiu R, Zhao S, Shen L, Tang B, Weng Q, Xu Z, Zheng L, Chen W, Shu G, Wang Y, Zhao Z, Chen M, Ji J
BMC biology 2022 Dec 27;20(1):294
BMC biology 2022 Dec 27;20(1):294
Targeting Cell Membranes, Depleting ROS by Dithiane and Thioketal-Containing Polymers with Pendant Cholesterols Delivering Necrostatin-1 for Glaucoma Treatment.
Rong R, Zhou X, Liang G, Li H, You M, Liang Z, Zeng Z, Xiao H, Ji D, Xia X
ACS nano 2022 Dec 27;16(12):21225-21239
ACS nano 2022 Dec 27;16(12):21225-21239
4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer.
Wang Y, Lei J, Zhang S, Wang X, Jin J, Liu Y, Gan M, Yuan Y, Sun L, Li X, Han T, Wang JB
Cell death & disease 2022 Dec 27;13(12):1075
Cell death & disease 2022 Dec 27;13(12):1075
MALAT1 modulates alternative splicing by cooperating with the splicing factors PTBP1 and PSF.
Miao H, Wu F, Li Y, Qin C, Zhao Y, Xie M, Dai H, Yao H, Cai H, Wang Q, Song X, Li L
Science advances 2022 Dec 23;8(51):eabq7289
Science advances 2022 Dec 23;8(51):eabq7289
Prognostic and therapeutic implication of m6A methylation in Crohn disease.
He Y, Hu Y, Yuan M, Xu W, Du Y, Liu J
Medicine 2022 Dec 23;101(51):e32399
Medicine 2022 Dec 23;101(51):e32399
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation.
Lim RG, Al-Dalahmah O, Wu J, Gold MP, Reidling JC, Tang G, Adam M, Dansu DK, Park HJ, Casaccia P, Miramontes R, Reyes-Ortiz AM, Lau A, Hickman RA, Khan F, Paryani F, Tang A, Ofori K, Miyoshi E, Michael N, McClure N, Flowers XE, Vonsattel JP, Davidson S, Menon V, Swarup V, Fraenkel E, Goldman JE, Thompson LM
Nature communications 2022 Dec 21;13(1):7791
Nature communications 2022 Dec 21;13(1):7791
Myo-Inositol Supplementation Alleviates Cisplatin-Induced Acute Kidney Injury via Inhibition of Ferroptosis.
Qi H, Deng F, Wang Y, Zhang H, Kanwar YS, Dai Y
Cells 2022 Dec 21;12(1)
Cells 2022 Dec 21;12(1)
β-hydroxybutyrate inhibits ferroptosis-mediated pancreatic damage in acute liver failure through the increase of H3K9bhb.
Zheng Y, Sun W, Shan C, Li B, Liu J, Xing H, Xu Q, Cui B, Zhu W, Chen J, Liu L, Yang T, Sun N, Li X
Cell reports 2022 Dec 20;41(12):111847
Cell reports 2022 Dec 20;41(12):111847
The Ginsenoside Compound K Suppresses Stem-Cell-like Properties and Colorectal Cancer Metastasis by Targeting Hypoxia-Driven Nur77-Akt Feed-Forward Signaling.
Zhang M, Shi Z, Zhang S, Li X, To SKY, Peng Y, Liu J, Chen S, Hu H, Wong AST, Zeng JZ
Cancers 2022 Dec 20;15(1)
Cancers 2022 Dec 20;15(1)
A multifunctional black phosphorus-based adhesive patch intrinsically induces partial EMT for effective burn wound healing.
Wang X, Tang X, Li N, Sun Y, Yu R, Zhang J, Li D, Yang B, Sun H
Biomaterials science 2022 Dec 20;11(1):235-247
Biomaterials science 2022 Dec 20;11(1):235-247
LncRNA ELF3-AS1 inhibits gastric cancer by forming a negative feedback loop with SNAI2 and regulates ELF3 mRNA stability via interacting with ILF2/ILF3 complex.
Li D, Shen L, Zhang X, Chen Z, Huang P, Huang C, Qin S
Journal of experimental & clinical cancer research : CR 2022 Dec 2;41(1):332
Journal of experimental & clinical cancer research : CR 2022 Dec 2;41(1):332
Targeting regulation of VEGF by BPTF in non-small cell lung cancer and its potential clinical significance.
Dai M, Hua C, Wang M, Gao L, Jiang L, Liu Y
European journal of medical research 2022 Dec 19;27(1):299
European journal of medical research 2022 Dec 19;27(1):299
Long noncoding RNA HOTAIR facilitates pulmonary vascular endothelial cell apoptosis via DNMT1 mediated hypermethylation of Bcl-2 promoter in COPD.
Dai Z, Liu X, Zeng H, Chen Y
Respiratory research 2022 Dec 17;23(1):356
Respiratory research 2022 Dec 17;23(1):356
Electroacupuncture Alleviates Neuroinflammation by Inhibiting the HMGB1 Signaling Pathway in Rats with Sepsis-Associated Encephalopathy.
Xin Y, Wang J, Chu T, Zhou Y, Liu C, Xu A
Brain sciences 2022 Dec 17;12(12)
Brain sciences 2022 Dec 17;12(12)
Fluid shear stress-induced down-regulation of miR-146a-5p inhibits osteoblast apoptosis via targeting SMAD4.
Liu X, Zhang K, Wang L, Geng B, Liu Z, Yi Q, Xia Y
Physiological research 2022 Dec 16;71(6):835-848
Physiological research 2022 Dec 16;71(6):835-848
Inhibition of TIGAR Increases Exogenous p53 and Cisplatin Combination Sensitivity in Lung Cancer Cells by Regulating Glycolytic Flux.
Fu J, Yu S, Zhao X, Zhang C, Shen L, Liu Y, Yu H
International journal of molecular sciences 2022 Dec 16;23(24)
International journal of molecular sciences 2022 Dec 16;23(24)
Genome-Wide Analysis of Circular RNAs Reveals circCHRNG Regulates Sheep Myoblast Proliferation via miR-133/SRF and MEF2A Axis.
Liu Y, Chen Q, Bao J, Pu Y, Han J, Zhao H, Ma Y, Zhao Q
International journal of molecular sciences 2022 Dec 16;23(24)
International journal of molecular sciences 2022 Dec 16;23(24)
Polystyrene Microplastics Postpone APAP-Induced Liver Injury through Impeding Macrophage Polarization.
Liu J, Zhang L, Xu F, Meng S, Li H, Song Y
Toxics 2022 Dec 16;10(12)
Toxics 2022 Dec 16;10(12)
The selective NLRP3 inflammasome inhibitor MCC950 improves isoproterenol-induced cardiac dysfunction by inhibiting cardiomyocyte senescence.
Shi Y, Zhao L, Wang J, Liu S, Zhang Y, Qin Q
European journal of pharmacology 2022 Dec 15;937:175364
European journal of pharmacology 2022 Dec 15;937:175364
Energy sensor AMPK gamma regulates translation via phosphatase PPP6C independent of AMPK alpha.
Zhou Q, Hao B, Cao X, Gao L, Yu Z, Zhao Y, Zhu M, Zhong G, Chi F, Dai X, Mao J, Zhu Y, Rong P, Chen L, Bai X, Ye C, Chen S, Liang T, Li L, Feng XH, Tan M, Zhao B
Molecular cell 2022 Dec 15;82(24):4700-4711.e12
Molecular cell 2022 Dec 15;82(24):4700-4711.e12
PRL stimulates mitotic errors by suppressing kinetochore-localized activation of AMPK during mitosis.
Ryu K, Yoshida A, Funato Y, Yamazaki D, Miki H
Cell structure and function 2022 Dec 15;47(2):75-87
Cell structure and function 2022 Dec 15;47(2):75-87
Ferroptosis as a mechanism of oligodendrocyte loss and demyelination in experimental autoimmune encephalomyelitis.
Li X, Chu Y, Ma R, Dou M, Li S, Song Y, Lv Y, Zhu L
Journal of neuroimmunology 2022 Dec 15;373:577995
Journal of neuroimmunology 2022 Dec 15;373:577995
Role of Ero1α in cognitive impairment induced by chronic hypoxia.
Zhang N, Shentu Y, Zhu M, Wang H, Yin X, Du C, Xue F, Fan J, Gong Y, Fan X
Brain research 2022 Dec 15;1797:148117
Brain research 2022 Dec 15;1797:148117
Fine-tuning of mTOR signaling by the UBE4B-KLHL22 E3 ubiquitin ligase cascade in brain development.
Kong X, Shu X, Wang J, Liu D, Ni Y, Zhao W, Wang L, Gao Z, Chen J, Yang B, Guo X, Wang Z
Development (Cambridge, England) 2022 Dec 15;149(24)
Development (Cambridge, England) 2022 Dec 15;149(24)
Coxsackievirus Group B3 Has Oncolytic Activity against Colon Cancer through Gasdermin E-Mediated Pyroptosis.
Zhang Y, Xu T, Tian H, Wu J, Yu X, Zeng L, Liu F, Liu Q, Huang X
Cancers 2022 Dec 15;14(24)
Cancers 2022 Dec 15;14(24)
Matrix protein Tenascin-C promotes kidney fibrosis via STAT3 activation in response to tubular injury.
Xie Q, Zhang M, Mao X, Xu M, Liu S, Shang D, Xu Y, Chen R, Guan Y, Huang X, Zent R, Pozzi A, Hao CM
Cell death & disease 2022 Dec 15;13(12):1044
Cell death & disease 2022 Dec 15;13(12):1044
Fecal Microbiota Transplantation Alleviated Cerebral Ischemia Reperfusion Injury in Obese Rats.
Xie T, Yang R, Zhang X, Shen X, Yu L, Liao J, Bao T, Fang Q
The Tohoku journal of experimental medicine 2022 Dec 14;259(1):49-55
The Tohoku journal of experimental medicine 2022 Dec 14;259(1):49-55
miR21 modulates the Hippo signaling pathway via interference with PP2A Bβ to inhibit trophoblast invasion and cause preeclampsia.
Hu M, Zheng Y, Liao J, Wen L, Cheng J, Huang J, Huang B, Lin L, Long Y, Wu Y, Ye X, Fu Y, Qi H, Baker PN, Tong C
Molecular therapy. Nucleic acids 2022 Dec 13;30:143-161
Molecular therapy. Nucleic acids 2022 Dec 13;30:143-161
PINK1/Parkin-Mediated Mitophagy Partially Protects against Inorganic Arsenic-Induced Hepatic Macrophage Polarization in Acute Arsenic-Exposed Mice.
Qu G, Liu Z, Zhang J, Guo Y, Li H, Qu R, Su W, Zhang H, Zhang L, Xu H, Shen F, Jiang S, Liu H, Li J
Molecules (Basel, Switzerland) 2022 Dec 13;27(24)
Molecules (Basel, Switzerland) 2022 Dec 13;27(24)
Treadmill training mitigates bone deterioration via inhibiting NLRP3/Caspase1/IL-1β signaling in aged rats.
Wu Q, Zhong P, Ning P, Tan L, Huang X, Peng T, Yin L, Luo F, Qu M, Zhou J
BMC musculoskeletal disorders 2022 Dec 13;23(1):1089
BMC musculoskeletal disorders 2022 Dec 13;23(1):1089
Silibinin Overcomes EMT-Driven Lung Cancer Resistance to New-Generation ALK Inhibitors.
Verdura S, Encinar JA, Teixidor E, Segura-Carretero A, Micol V, Cuyàs E, Bosch-Barrera J, Menendez JA
Cancers 2022 Dec 11;14(24)
Cancers 2022 Dec 11;14(24)
DEXMEDETOMIDINE PREVENTS PDIA3 DECREASE BY ACTIVATING α2-ADRENERGIC RECEPTOR TO ALLEVIATE INTESTINAL I/R IN MICE.
Zhan Y, Chen Z, Qiu Y, Deng Q, Huang W, Wen S, Shen J
Shock (Augusta, Ga.) 2022 Dec 1;58(6):556-564
Shock (Augusta, Ga.) 2022 Dec 1;58(6):556-564
Non-canonical phosphoglycerate dehydrogenase activity promotes liver cancer growth via mitochondrial translation and respiratory metabolism.
Shu Y, Hao Y, Feng J, Liu H, Li ST, Feng J, Jiang Z, Ye L, Zhou Y, Sun Y, Zhou Z, Wei H, Gao P, Zhang H, Sun L
The EMBO journal 2022 Dec 1;41(23):e111550
The EMBO journal 2022 Dec 1;41(23):e111550
COOH-terminal fragment of APP interacts with p62, forms an aggregate, and induces autophagic degradation in Alzheimer's cell model.
Tanaka K, Kuramoto K, Nakagawa T, Nomura Y, Ozawa K, Hosoi T
American journal of physiology. Cell physiology 2022 Dec 1;323(6):C1633-C1641
American journal of physiology. Cell physiology 2022 Dec 1;323(6):C1633-C1641
Aloe polymeric acemannan inhibits the cytokine storm in mouse pneumonia models by modulating macrophage metabolism.
Li L, Xu W, Luo Y, Lao C, Tong X, Du J, Huang B, Li D, Chen J, Ye H, Cong F, Guo X, Li J
Carbohydrate polymers 2022 Dec 1;297:120032
Carbohydrate polymers 2022 Dec 1;297:120032
Alleviating effects of selenium on fluoride-induced testosterone synthesis disorder and reproduction toxicity in rats.
Zhao H, Zhu Y, Zhao Y, Wang T, Li H, Yang J, Cheng X, Wang J, Wang J
Ecotoxicology and environmental safety 2022 Dec 1;247:114249
Ecotoxicology and environmental safety 2022 Dec 1;247:114249
Fucoidan ameliorates LPS-induced neuronal cell damage and cognitive impairment in mice.
Wang Y, Wang Q, Duan L, Li X, Yang W, Huang T, Kong M, Guan F, Ma S
International journal of biological macromolecules 2022 Dec 1;222(Pt A):759-771
International journal of biological macromolecules 2022 Dec 1;222(Pt A):759-771
Resveratrol activates the SIRT1/PGC-1 pathway in mice to improve synaptic-related cognitive impairment after TBI.
Yu D, Zhao XY, Meng QP, Teng D, Deng K, Lin N
Brain research 2022 Dec 1;1796:148109
Brain research 2022 Dec 1;1796:148109
Subchronic Oral Cylindrospermopsin Exposure Alters the Host Gut Microbiome and Is Associated with Progressive Hepatic Inflammation, Stellate Cell Activation, and Mild Fibrosis in a Preclinical Study.
Saha P, Upright M, Bose D, Roy S, Trivedi A, More M, Scott GI, Brooks BW, Chatterjee S
Toxins 2022 Dec 1;14(12)
Toxins 2022 Dec 1;14(12)
Intestinal epithelial β Klotho is a critical protective factor in alcohol-induced intestinal barrier dysfunction and liver injury.
Hou Z, Ding Q, Li Y, Zhao Z, Yan F, Li Y, Wang X, Xu J, Chen W, Wu G, Ruan X, Zhao L
EBioMedicine 2022 Aug;82:104181
EBioMedicine 2022 Aug;82:104181
Suppression of nitric oxide synthase aggravates non-alcoholic steatohepatitis and atherosclerosis in SHRSP5/Dmcr rat via acceleration of abnormal lipid metabolism.
Sato I, Yamamoto S, Kakimoto M, Fujii M, Honma K, Kumazaki S, Matsui M, Nakayama H, Kirihara S, Ran S, Usui S, Shinohata R, Kitamori K, Hirohata S, Watanabe S
Pharmacological reports : PR 2022 Aug;74(4):669-683
Pharmacological reports : PR 2022 Aug;74(4):669-683
Porphyromonas gingivalis lipopolysaccharide affects the angiogenic function of endothelial progenitor cells via Akt/FoxO1 signaling.
Deng H, Gong Y, Chen Y, Zhang G, Chen H, Cheng T, Jin L, Wang Y
Journal of periodontal research 2022 Aug;57(4):859-868
Journal of periodontal research 2022 Aug;57(4):859-868
Mesenchymal stem cell-exosome-mediated matrix metalloproteinase 1 participates in oral leukoplakia and carcinogenesis by inducing angiogenesis.
Li S, Han Y, Lu M, Liu Z, Jin J, Guo Q, Wang Y, Liu H
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2022 Aug;51(7):638-648
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2022 Aug;51(7):638-648
Umbilical cord-derived mesenchymal stem cell conditioned medium reverses neuronal oxidative injury by inhibition of TRPM2 activation and the JNK signaling pathway.
Wang Y, Liu J, Yu B, Jin Y, Li J, Ma X, Yu J, Niu J, Liang X
Molecular biology reports 2022 Aug;49(8):7337-7345
Molecular biology reports 2022 Aug;49(8):7337-7345
Oxidative stress and Cx43-mediated apoptosis are involved in PFOS-induced nephrotoxicity.
Tang L, Yu J, Zhuge S, Chen H, Zhang L, Jiang G
Toxicology 2022 Aug;478:153283
Toxicology 2022 Aug;478:153283
Transcriptional regulator CTR9 promotes hepatocellular carcinoma progression and metastasis via increasing PEG10 transcriptional activity.
Zhang B, Liu ZY, Wu R, Zhang CM, Cao K, Shan WG, Liu Z, Ji M, Tian ZL, Sethi G, Shi HL, Wang RH
Acta pharmacologica Sinica 2022 Aug;43(8):2109-2118
Acta pharmacologica Sinica 2022 Aug;43(8):2109-2118
Alteration of the neuronal and glial cell profiles in Neu1-deficient zebrafish.
Ikeda A, Yamasaki C, Kubo Y, Doi Y, Komamizu M, Komatsu M, Shiozaki K
Glycoconjugate journal 2022 Aug;39(4):499-512
Glycoconjugate journal 2022 Aug;39(4):499-512
Extracellular HSP90α promotes cellular senescence by modulating TGF-β signaling in pulmonary fibrosis.
Zhong W, Chen W, Liu Y, Zhang J, Lu Y, Wan X, Qiao Y, Huang H, Zeng Z, Li W, Meng X, Zhao H, Zou M, Cai S, Dong H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Aug;36(8):e22475
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Aug;36(8):e22475
Targeted Disruption of a Proximal Tubule-Specific TMEM174 Gene in Mice Causes Hyperphosphatemia and Vascular Calcification.
Miyazaki-Anzai S, Keenan AL, Blaine J, Miyazaki M
Journal of the American Society of Nephrology : JASN 2022 Aug;33(8):1477-1486
Journal of the American Society of Nephrology : JASN 2022 Aug;33(8):1477-1486
GRASP55 regulates the unconventional secretion and aggregation of mutant huntingtin.
Ahat E, Bui S, Zhang J, da Veiga Leprevost F, Sharkey L, Reid W, Nesvizhskii AI, Paulson HL, Wang Y
The Journal of biological chemistry 2022 Aug;298(8):102219
The Journal of biological chemistry 2022 Aug;298(8):102219
Nuclear ribonucleoprotein RALY targets virus nucleocapsid protein and induces autophagy to restrict porcine epidemic diarrhea virus replication.
Qin W, Kong N, Zhang Y, Dong S, Zhai H, Zhai X, Yang X, Ye C, Ye M, Liu C, Yu L, Zheng H, Yu H, Zhang W, Tong G, Lan D, Tong W, Shan T
The Journal of biological chemistry 2022 Aug;298(8):102190
The Journal of biological chemistry 2022 Aug;298(8):102190
MgIG exerts therapeutic effects on crizotinib-induced hepatotoxicity by limiting ROS-mediated autophagy and pyroptosis.
Li M, Wang C, Yu Z, Lan Q, Xu S, Ye Z, Li R, Ying L, Zhang X, Zhou Z
Journal of cellular and molecular medicine 2022 Aug;26(16):4492-4505
Journal of cellular and molecular medicine 2022 Aug;26(16):4492-4505
Human breast milk-derived exosomes through inhibiting AT II cell apoptosis to prevent bronchopulmonary dysplasia in rat lung.
Zhou Y, Liu Y, Xu G, Liu L, Li H, Li Y, Yin J, Wang X, Yu Z
Journal of cellular and molecular medicine 2022 Aug;26(15):4169-4182
Journal of cellular and molecular medicine 2022 Aug;26(15):4169-4182
The transcription factor TOX is involved in the regulation of T-cell exhaustion in neuroblastoma.
Pei M, Chai W, Wang X, Duan Y, Wang H, Xi Y, Mou W, Wang W, Chen X, Zhang H, Li Q, Song W, Wang H, Ma X, Gui J
Immunology letters 2022 Aug;248:16-25
Immunology letters 2022 Aug;248:16-25
Cyclometalated iridium(III) dithioformic acid complexes as mitochondria-targeted imaging and anticancer agents.
Wu Y, Liu J, Shao M, Zhang P, Song S, Yang G, Liu X, Liu Z
Journal of inorganic biochemistry 2022 Aug;233:111855
Journal of inorganic biochemistry 2022 Aug;233:111855
Anti-inflammatory Properties of the Alpha-Melanocyte-Stimulating Hormone in Models of Granulomatous Inflammation.
Shahraki AH, Tian R, Zhang C, Fregien NL, Bejarano P, Mirsaeidi M
Lung 2022 Aug;200(4):463-472
Lung 2022 Aug;200(4):463-472
Guanxinning tablet inhibits the interaction between leukocyte integrin Mac-1 and platelet GPIbα for antithrombosis without increased bleeding risk.
Yang QQ, Fang MS, Tu J, Ma QX, Shen LY, Xu YY, Chen J, Chen ML
Chinese journal of natural medicines 2022 Aug;20(8):589-600
Chinese journal of natural medicines 2022 Aug;20(8):589-600
DDIT3/CHOP mediates the inhibitory effect of ER stress on chondrocyte differentiation by AMPKα-SIRT1 pathway.
Yu X, Xu X, Dong W, Yang C, Luo Y, He Y, Jiang C, Wu Y, Wang J
Biochimica et biophysica acta. Molecular cell research 2022 Aug;1869(8):119265
Biochimica et biophysica acta. Molecular cell research 2022 Aug;1869(8):119265
Cullin-associated and neddylation-dissociated 1 protein (CAND1) governs cardiac hypertrophy and heart failure partially through regulating calcineurin degradation.
Li X, Zhang Y, Zhao Y, Zhou Y, Han Q, Yang Y, Zhang L, Shi L, Jin X, Zhang R, Gao H, Xue G, Li D, Zhang ZR, Lu Y, Yang B, Pan Z
Pharmacological research 2022 Aug;182:106284
Pharmacological research 2022 Aug;182:106284
Leonurine alleviates ferroptosis in cisplatin-induced acute kidney injury by activating the Nrf2 signalling pathway.
Hu J, Gu W, Ma N, Fan X, Ci X
British journal of pharmacology 2022 Aug;179(15):3991-4009
British journal of pharmacology 2022 Aug;179(15):3991-4009
NSUN2-mediated RNA m(5)C modification modulates uveal melanoma cell proliferation and migration.
Luo G, Xu W, Chen X, Wang S, Wang J, Dong F, Hu DN, Reinach PS, Yan D
Epigenetics 2022 Aug;17(8):922-933
Epigenetics 2022 Aug;17(8):922-933
Neuropeptide Y promotes hepatic apolipoprotein A1 synthesis and secretion through neuropeptide Y Y5 receptor.
Liu B, Chen F
Peptides 2022 Aug;154:170824
Peptides 2022 Aug;154:170824
Modification of taxifolin particles with an enteric coating material promotes repair of acute liver injury in mice through modulation of inflammation and autophagy signaling pathway.
Ding Q, Chen K, Liu X, Ding C, Zhao Y, Sun S, Zhang Y, Zhang J, Liu S, Liu W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Aug;152:113242
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Aug;152:113242
TPN171H alleviates pulmonary hypertension via inhibiting inflammation in hypoxia and monocrotaline-induced rats.
Zhao C, Hu L, He X, Li L, Yin M, Tettey AT, Wang Y, Shen J, Tang S, Wu C, Li Q, Wang Z, Li X
Vascular pharmacology 2022 Aug;145:107017
Vascular pharmacology 2022 Aug;145:107017
Microbial and metabolic profiles of bronchopulmonary dysplasia and therapeutic effects of potential probiotics Limosilactobacillus reuteri and Bifidobacterium bifidum.
Li Y, He L, Zhao Q, Bo T
Journal of applied microbiology 2022 Aug;133(2):908-921
Journal of applied microbiology 2022 Aug;133(2):908-921
Bacillus subtilis WB800N alleviates diabetic wounds in mice by regulating gut microbiota homeostasis and TLR2.
Mi J, Xie C, Zeng L, Zhu Z, Chen N, He Q, Xu X, Xie H, Zhou J, Li L, Liao J
Journal of applied microbiology 2022 Aug;133(2):436-447
Journal of applied microbiology 2022 Aug;133(2):436-447
Neomycin inhibits Megalocytivirus infection in fish by antagonizing the increase of intracellular reduced glutathione.
Deng H, Li Y, Li J, Shen W, Chen Q, Weng S, He J, Xu X
Fish & shellfish immunology 2022 Aug;127:148-154
Fish & shellfish immunology 2022 Aug;127:148-154
LncRNA SNHG11 promotes the malignant transformation of human bronchial epithelial cells induced by beryllium sulfate.
Deng W, Sun Z, Chen S, Li G, Liu X, Huang L, Zhang Z
Toxicology research 2022 Aug;11(4):605-615
Toxicology research 2022 Aug;11(4):605-615
High-fructose corn syrup promotes proinflammatory Macrophage activation via ROS-mediated NF-κB signaling and exacerbates colitis in mice.
Wang L, Ji T, Yuan Y, Fu H, Wang Y, Tian S, Hu J, Wang L, Wang Z
International immunopharmacology 2022 Aug;109:108814
International immunopharmacology 2022 Aug;109:108814
Paeoniflorin ameliorates diabetic liver injury by targeting the TXNIP-mediated NLRP3 inflammasome in db/db mice.
Wang A, Gong Y, Pei Z, Jiang L, Xia L, Wu Y
International immunopharmacology 2022 Aug;109:108792
International immunopharmacology 2022 Aug;109:108792
Burdock (Arctium lappa L.) leaf flavonoids rich in morin and quercetin 3-O-rhamnoside ameliorate lipopolysaccharide-induced inflammation and oxidative stress in RAW264.7 cells.
Cui J, Zong W, Zhao N, Yuan R
Food science & nutrition 2022 Aug;10(8):2718-2726
Food science & nutrition 2022 Aug;10(8):2718-2726
High-affinity SOAT1 ligands remodeled cholesterol metabolism program to inhibit tumor growth.
Wang Z, Wang M, Zhang M, Xu K, Zhang X, Xie Y, Zhang Y, Chang C, Li X, Sun A, He F
BMC medicine 2022 Aug 9;20(1):292
BMC medicine 2022 Aug 9;20(1):292
The inhibitory effect and mechanism of Yi-qi-hua-yu-jie-du decoction on the drug resistance of gastric cancer stem cells based on ABC transporters.
Huang W, Wen F, Gu P, Liu J, Xia Y, Li Y, Zhou J, Song S, Ruan S, Gu S, Chen X, Shu P
Chinese medicine 2022 Aug 9;17(1):93
Chinese medicine 2022 Aug 9;17(1):93
Pharmacological induction of AMFR increases functional EAAT2 oligomer levels and reduces epileptic seizures in mice.
Sha L, Li G, Zhang X, Lin Y, Qiu Y, Deng Y, Zhu W, Xu Q
JCI insight 2022 Aug 8;7(15)
JCI insight 2022 Aug 8;7(15)
Construction of Attenuated Strains for Red-Spotted Grouper Nervous Necrosis Virus (RGNNV) via Reverse Genetic System.
Lei Y, Xiong Y, Tao D, Wang T, Chen T, Du X, Cao G, Tu J, Dai J
Viruses 2022 Aug 6;14(8)
Viruses 2022 Aug 6;14(8)
The mechanism of the imbalance between proliferation and ferroptosis in pulmonary artery smooth muscle cells based on the activation of SLC7A11.
Hu P, Xu Y, Jiang Y, Huang J, Liu Y, Wang D, Tao T, Sun Z, Liu Y
European journal of pharmacology 2022 Aug 5;928:175093
European journal of pharmacology 2022 Aug 5;928:175093
Retinal Src homology region 2-containing protein tyrosine phosphatase 2 silencing alleviates diabetic retinopathy via suppressing inflammatory response and oxidative stress by regulating Yes-associated protein 1 activity.
Han N, Su Y, Guo M, Yu L
Experimental animals 2022 Aug 5;71(3):376-384
Experimental animals 2022 Aug 5;71(3):376-384
Incomplete autophagy promotes the proliferation of Mycoplasma hyopneumoniae through the JNK and Akt pathways in porcine alveolar macrophages.
Wen Y, Chen Z, Tian Y, Yang M, Dong Q, Yang Y, Ding H
Veterinary research 2022 Aug 4;53(1):62
Veterinary research 2022 Aug 4;53(1):62
6-Hydroxydopamine-Induced Neurotoxicity in Rat Model of Parkinson's Disease: Is Reversed via Anti-Oxidative Activities of Curcumin and Aerobic Exercise Therapy.
Sokouti H, Mohajeri D, Nourazar MA
Physiological research 2022 Aug 31;71(4):551-560
Physiological research 2022 Aug 31;71(4):551-560
Kaempferol-Driven Inhibition of Listeriolysin O Pore Formation and Inflammation Suppresses Listeria monocytogenes Infection.
Wang T, Liu B, Zhang C, Fang T, Ding Y, Song G, Zhang S, Shi L, Deng X, Wang J
Microbiology spectrum 2022 Aug 31;10(4):e0181022
Microbiology spectrum 2022 Aug 31;10(4):e0181022
GNIP1 functions both as a scaffold protein and an E3 ubiquitin ligase to regulate autophagy in lung cancer.
Zhou F, Liu Y, Ai W, Wang Y, Gan M, Jiang Q, Han T, Wang JB
Cell communication and signaling : CCS 2022 Aug 30;20(1):133
Cell communication and signaling : CCS 2022 Aug 30;20(1):133
LncRNA H19 inhibits ER stress induced apoptosis and improves diabetic cardiomyopathy by regulating PI3K/AKT/mTOR axis.
Wang S, Duan J, Liao J, Wang Y, Xiao X, Li L, Liu Y, Gu H, Yang P, Fu D, Du J, Li X, Shao M
Aging 2022 Aug 30;14(16):6809-6828
Aging 2022 Aug 30;14(16):6809-6828
Dual antioxidant activity and the related mechanisms of a novel pentapeptide GLP4 from the fermented mycelia of Ganoderma lingzhi.
Huang P, Luo FJ, Ma YC, Wang SX, Huang J, Qin DD, Xue FF, Liu BY, Wu Q, Wang XL, Liu GQ
Food & function 2022 Aug 30;13(17):9032-9048
Food & function 2022 Aug 30;13(17):9032-9048
Circ_0047339 promotes the activation of fibroblasts and affects the development of urethral stricture by targeting the miR-4691-5p/TSP-1 axis.
Ding K, Li D, Zhang R, Zuo M
Scientific reports 2022 Aug 30;12(1):14746
Scientific reports 2022 Aug 30;12(1):14746
Downregulation of IL-8 and IL-10 by the Activation of Ca(2+)-Activated K(+) Channel K(Ca)3.1 in THP-1-Derived M(2) Macrophages.
Ohya S, Matsui M, Kajikuri J, Kito H, Endo K
International journal of molecular sciences 2022 Aug 3;23(15)
International journal of molecular sciences 2022 Aug 3;23(15)
Effects of MICU1-Mediated Mitochondrial Calcium Uptake on Energy Metabolism and Quality of Vitrified-Thawed Mouse Metaphase II Oocytes.
Lan T, Zhang K, Lin F, He Q, Wu S, Xu Z, Zhang Y, Quan F
International journal of molecular sciences 2022 Aug 3;23(15)
International journal of molecular sciences 2022 Aug 3;23(15)
Cornuside Is a Potential Agent against Alzheimer's Disease via Orchestration of Reactive Astrocytes.
Shi JZ, Zheng XM, Zhou YF, Yun LY, Luo DM, Hao JJ, Liu PF, Zhang WK, Xu JK, Yan Y, Xie XM, He YY, Pang XB
Nutrients 2022 Aug 3;14(15)
Nutrients 2022 Aug 3;14(15)
Staphylococcus aureus-Induced Necroptosis Promotes Mitochondrial Damage in Goat Endometrial Epithelial Cells.
Yi Y, Gao K, Lin P, Chen H, Zhou D, Tang K, Wang A, Jin Y
Animals : an open access journal from MDPI 2022 Aug 29;12(17)
Animals : an open access journal from MDPI 2022 Aug 29;12(17)
The mechanism of Yinchenhao decoction in treating obstructive-jaundice-induced liver injury based on Nrf2 signaling pathway.
Liu JJ, Xu Y, Chen S, Hao CF, Liang J, Li ZL
World journal of gastroenterology 2022 Aug 28;28(32):4635-4648
World journal of gastroenterology 2022 Aug 28;28(32):4635-4648
Rhodococcus equi-Derived Extracellular Vesicles Promoting Inflammatory Response in Macrophage through TLR2-NF-κB/MAPK Pathways.
Xu Z, Hao X, Li M, Luo H
International journal of molecular sciences 2022 Aug 28;23(17)
International journal of molecular sciences 2022 Aug 28;23(17)
Mesenchymal stem cells-derived exosomes prevent sepsis-induced myocardial injury by a CircRTN4/miR-497-5p/MG53 pathway.
Li J, Jiang R, Hou Y, Lin A
Biochemical and biophysical research communications 2022 Aug 27;618:133-140
Biochemical and biophysical research communications 2022 Aug 27;618:133-140
ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection.
Karki R, Lee S, Mall R, Pandian N, Wang Y, Sharma BR, Malireddi RS, Yang D, Trifkovic S, Steele JA, Connelly JP, Vishwanath G, Sasikala M, Reddy DN, Vogel P, Pruett-Miller SM, Webby R, Jonsson CB, Kanneganti TD
Science immunology 2022 Aug 26;7(74):eabo6294
Science immunology 2022 Aug 26;7(74):eabo6294
BRAT1 links Integrator and defective RNA processing with neurodegeneration.
Cihlarova Z, Kubovciak J, Sobol M, Krejcikova K, Sachova J, Kolar M, Stanek D, Barinka C, Yoon G, Caldecott KW, Hanzlikova H
Nature communications 2022 Aug 26;13(1):5026
Nature communications 2022 Aug 26;13(1):5026
Breaking the Iron Homeostasis: A "Trojan Horse" Self-Assembled Nanodrug Sensitizes Homologous Recombination Proficient Ovarian Cancer Cells to PARP Inhibition.
Li Y, Cen Y, Fang Y, Tang S, Li S, Ren Y, Zhang H, Lu W, Xu J
ACS nano 2022 Aug 23;16(8):12786-12800
ACS nano 2022 Aug 23;16(8):12786-12800
Neu1 deficiency increases the susceptibility of zebrafish to Edwardsiella piscicida infection via lysosomal dysfunction.
Sahashi D, Kubo Y, Ishii M, Ikeda A, Yamasaki C, Komatsu M, Shiozaki K
Gene 2022 Aug 20;836:146667
Gene 2022 Aug 20;836:146667
Diallyl trisulfide sensitizes radiation therapy on glioblastoma through directly targeting thioredoxin 1.
Tian Y, Ge Z, Xu M, Ge X, Zhao M, Ding F, Yin J, Wang X, You Y, Shi Z, Qian X
Free radical biology & medicine 2022 Aug 20;189:157-168
Free radical biology & medicine 2022 Aug 20;189:157-168
GPT2 Is Induced by Hypoxia-Inducible Factor (HIF)-2 and Promotes Glioblastoma Growth.
Zhang B, Chen Y, Bao L, Luo W
Cells 2022 Aug 20;11(16)
Cells 2022 Aug 20;11(16)
Quantitative Acetylomics Uncover Acetylation-Mediated Pathway Changes Following Histone Deacetylase Inhibition in Anaplastic Large Cell Lymphoma.
Zrimšek M, Kuchaříková H, Draganić K, Dobrovolná P, Heiss Spornberger V, Winkelmayer L, Hassler MR, Lochmanová G, Zdráhal Z, Egger G
Cells 2022 Aug 2;11(15)
Cells 2022 Aug 2;11(15)
Single-cell atlas of diverse immune populations in the advanced biliary tract cancer microenvironment.
Shi X, Li Z, Yao R, Cheng Q, Li W, Wu R, Xie Z, Zhu Y, Qiu X, Yang S, Zhou T, Hu J, Zhang Y, Wu T, Zhao Y, Zhang Y, Wu J, Wang H, Jiang X, Chen L
NPJ precision oncology 2022 Aug 18;6(1):58
NPJ precision oncology 2022 Aug 18;6(1):58
Developmental differences of in vitro cultured murine bone marrow- and fetal liver-derived megakaryocytes.
Bertović I, Bura A, Jurak Begonja A
Platelets 2022 Aug 18;33(6):887-899
Platelets 2022 Aug 18;33(6):887-899
A Novel Pectin-Like Glycopeptide Isolated from the Fruit of Fructus Mori Impedes Aggregation and Production of Aβ(42).
Li S, Jin C, Gao P, Zhou W, Xiao R, Zhang Z, Liao W, Ding K
Journal of agricultural and food chemistry 2022 Aug 17;70(32):9908-9918
Journal of agricultural and food chemistry 2022 Aug 17;70(32):9908-9918
YTHDC1 is downregulated by the YY1/HDAC2 complex and controls the sensitivity of ccRCC to sunitinib by targeting the ANXA1-MAPK pathway.
Li W, Ye K, Li X, Liu X, Peng M, Chen F, Xiong W, Wang Y, Zhu L
Journal of experimental & clinical cancer research : CR 2022 Aug 17;41(1):250
Journal of experimental & clinical cancer research : CR 2022 Aug 17;41(1):250
Phenolic Acids from Fructus Chebulae Immaturus Alleviate Intestinal Ischemia-Reperfusion Injury in Mice through the PPARα/NF-κB Pathway.
Liu J, Li B, Liu J, Qiu F, Diao Y, Lei Y, Liu J, Zhang W
Molecules (Basel, Switzerland) 2022 Aug 16;27(16)
Molecules (Basel, Switzerland) 2022 Aug 16;27(16)
Construction of a novel model based on cell-in-cell-related genes and validation of KRT7 as a biomarker for predicting survival and immune microenvironment in pancreatic cancer.
Song J, Ruze R, Chen Y, Xu R, Yin X, Wang C, Xu Q, Zhao Y
BMC cancer 2022 Aug 16;22(1):894
BMC cancer 2022 Aug 16;22(1):894
CD38 Mediates Lung Fibrosis by Promoting Alveolar Epithelial Cell Aging.
Cui H, Xie N, Banerjee S, Dey T, Liu RM, Antony VB, Sanders YY, Adams TS, Gomez JL, Thannickal VJ, Kaminski N, Liu G
American journal of respiratory and critical care medicine 2022 Aug 15;206(4):459-475
American journal of respiratory and critical care medicine 2022 Aug 15;206(4):459-475
Quantitative Proteomics Explore the Potential Targets and Action Mechanisms of Hydroxychloroquine.
Zhao J, Zhao Z, Hou W, Jiang Y, Liu G, Ren X, Liu K, Liu H, Chen K, Huang H
Molecules (Basel, Switzerland) 2022 Aug 14;27(16)
Molecules (Basel, Switzerland) 2022 Aug 14;27(16)
Inert Pepper aptamer-mediated endogenous mRNA recognition and imaging in living cells.
Wang Q, Xiao F, Su H, Liu H, Xu J, Tang H, Qin S, Fang Z, Lu Z, Wu J, Weng X, Zhou X
Nucleic acids research 2022 Aug 12;50(14):e84
Nucleic acids research 2022 Aug 12;50(14):e84
Melatonin ameliorates diabetic hyperglycaemia-induced impairment of Leydig cell steroidogenic function through activation of SIRT1 pathway.
Wang P, Zhang S, Lin S, Lv Z
Reproductive biology and endocrinology : RB&E 2022 Aug 12;20(1):117
Reproductive biology and endocrinology : RB&E 2022 Aug 12;20(1):117
The NS4A Protein of Classical Swine Fever Virus Suppresses RNA Silencing in Mammalian Cells.
Qian Q, Xu R, Wang Y, Ma L
Journal of virology 2022 Aug 10;96(15):e0187421
Journal of virology 2022 Aug 10;96(15):e0187421
Hsp70 Inhibits the Replication of Fowl Adenovirus Serotype 4 by Suppressing Viral Hexon with the Assistance of DnaJC7.
Cao J, Liu S, Liu M, Wang S, Bi Z, Fan W, Shi Z, Song S, Yan L
Journal of virology 2022 Aug 10;96(15):e0080722
Journal of virology 2022 Aug 10;96(15):e0080722
The effects of Jiawei Duhuo Jisheng mixture on Wnt/β-catenin signaling pathway in the synovium inflamed by knee osteoarthritis: An in vitro and in vivo experiment.
Shi Q, Huang L, Duan J, Kuang G, Lu M, Tan X
Journal of ethnopharmacology 2022 Aug 10;294:115363
Journal of ethnopharmacology 2022 Aug 10;294:115363
Jianpi Huayu decoction inhibits the epithelial-mesenchymal transition of hepatocellular carcinoma cells by suppressing exosomal miR-23a-3p/Smad signaling.
Xie CF, Feng KL, Wang JN, Luo R, Fang CK, Zhang Y, Shen CP, Zhong C
Journal of ethnopharmacology 2022 Aug 10;294:115360
Journal of ethnopharmacology 2022 Aug 10;294:115360
MAB21L1 promotes survival of lens epithelial cells through control of αB-crystallin and ATR/CHK1/p53 pathway.
Xiao Y, Xiang JW, Gao Q, Bai YY, Huang ZX, Hu XH, Wang L, Li DW
Aging 2022 Aug 10;14(15):6128-6148
Aging 2022 Aug 10;14(15):6128-6148
MDM2-mediated ubiquitination of LKB1 contributes to the development of diabetic cataract.
Li X, Sun X, Li L, Luo Y, Chi Y, Zheng G
Experimental cell research 2022 Aug 1;417(1):113191
Experimental cell research 2022 Aug 1;417(1):113191
Multifunctional chitin-based hollow nerve conduit for peripheral nerve regeneration and neuroma inhibition.
Yang X, Huang L, Yi X, Huang S, Duan B, Yu A
Carbohydrate polymers 2022 Aug 1;289:119443
Carbohydrate polymers 2022 Aug 1;289:119443
4-Octyl itaconate suppresses the osteogenic response in aortic valvular interstitial cells via the Nrf2 pathway and alleviates aortic stenosis in mice with direct wire injury.
Peng X, Su S, Zeng J, Xie K, Yang X, Xian G, Xiao Z, Zhu P, Zheng S, Xu D, Zeng Q
Free radical biology & medicine 2022 Aug 1;188:404-418
Free radical biology & medicine 2022 Aug 1;188:404-418
The Annexin A2-Notch regulatory loop in hepatocytes promotes liver fibrosis in NAFLD by increasing osteopontin expression.
Wang G, Duan J, Pu G, Ye C, Li Y, Xiu W, Xu J, Liu B, Zhu Y, Wang C
Biochimica et biophysica acta. Molecular basis of disease 2022 Aug 1;1868(8):166413
Biochimica et biophysica acta. Molecular basis of disease 2022 Aug 1;1868(8):166413
Tangeretin suppresses osteoarthritis progression via the Nrf2/NF-κB and MAPK/NF-κB signaling pathways.
Shi Y, Chen J, Li S, Wu Y, Yu C, Ni L, Xiao J, Shao Z, Zhu H, Wang J, Wang X, Zhang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Apr;98:153928
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Apr;98:153928
EML4-ALK G1202R mutation induces EMT and confers resistance to ceritinib in NSCLC cells via activation of STAT3/Slug signaling.
Shen J, Meng Y, Wang K, Gao M, Du J, Wang J, Li Z, Zuo D, Wu Y
Cellular signalling 2022 Apr;92:110264
Cellular signalling 2022 Apr;92:110264
c-Myc participates in high glucose-mediated endothelial inflammation via upregulation of IRAK1 expression in diabetic nephropathy.
Hou W, Lu L, Li X, Sun M, Zhu M, Miao C
Cellular signalling 2022 Apr;92:110263
Cellular signalling 2022 Apr;92:110263
LPS induces pulmonary microvascular endothelial cell barrier dysfunction by upregulating ceramide production.
Jiang J, Ouyang H, Zhou Q, Tang S, Fang P, Xie G, Yang J, Sun G
Cellular signalling 2022 Apr;92:110250
Cellular signalling 2022 Apr;92:110250
Decreased efficacy of the ketamine and scopolamine-induced sustained antidepressant-like effects in rats receiving metformin.
Chuang HW, Wei IH, Li CT, Huang CC
Pharmacological reports : PR 2022 Apr;74(2):340-352
Pharmacological reports : PR 2022 Apr;74(2):340-352
COP1 Acts as a Ubiquitin Ligase for PCDH9 Ubiquitination and Degradation in Human Glioma.
Zhou K, Wang L, Sun Z, Liu Y, Zhu Y, Liu Z, Zhang B, Shi H
Molecular neurobiology 2022 Apr;59(4):2378-2388
Molecular neurobiology 2022 Apr;59(4):2378-2388
Interleukin-17A Contributed to the Damage of Blood-CNS Barriers During Streptococcus suis Meningitis.
Xu L, Lu X, Xiao P, Liu R, Xia K, Wu M, Jin M, Zhang A
Molecular neurobiology 2022 Apr;59(4):2116-2128
Molecular neurobiology 2022 Apr;59(4):2116-2128
A comparison expression analysis of CXCR4, CXCL9 and Caspase-9 in dermal vascular endothelial cells between keloids and normal skin on chemotaxis and apoptosis.
Dong X, Zhang M, Chen Y, Li C, Wang Y, Jin X
Journal of plastic surgery and hand surgery 2022 Apr;56(2):93-102
Journal of plastic surgery and hand surgery 2022 Apr;56(2):93-102
Grem1 accelerates nucleus pulposus cell apoptosis and intervertebral disc degeneration by inhibiting TGF-β-mediated Smad2/3 phosphorylation.
Chen S, Lei L, Li Z, Chen F, Huang Y, Jiang G, Guo X, Zhao Z, Liu H, Wang H, Liu C, Zheng Z, Wang J
Experimental & molecular medicine 2022 Apr;54(4):518-530
Experimental & molecular medicine 2022 Apr;54(4):518-530
Enterobacter cloacae: a villain in CaOx stone disease?
Yang Y, Hong S, Xu J, Li C, Wang S, Xun Y
Urolithiasis 2022 Apr;50(2):177-188
Urolithiasis 2022 Apr;50(2):177-188
Linagliptin ameliorates pulmonary fibrosis in systemic sclerosis mouse model via inhibition of endothelial-to-mesenchymal transition.
Pei B, Zhang N, Pang T, Sun G
Molecular and cellular biochemistry 2022 Apr;477(4):995-1007
Molecular and cellular biochemistry 2022 Apr;477(4):995-1007
Functional characterization of human organic anion transporter 10 (OAT10/SLC22A13) as an orotate transporter.
Shinoda Y, Yamashiro T, Hosooka A, Yasujima T, Yuasa H
Drug metabolism and pharmacokinetics 2022 Apr;43:100443
Drug metabolism and pharmacokinetics 2022 Apr;43:100443
Early Aerobic Exercise Promotes Neurological Function Recovery of Rats after Cerebral Ischemia/Reperfusion by Upregulating the Expression of Heat Shock Protein A5.
Peng ZF, Zhang NB, Meng J, Zhang JH
Current medical science 2022 Apr;42(2):267-273
Current medical science 2022 Apr;42(2):267-273
MicroRNA-22 represses glioma development via activation of macrophage-mediated innate and adaptive immune responses.
Tu J, Fang Y, Han D, Tan X, Xu Z, Jiang H, Wang X, Hong W, Wei W
Oncogene 2022 Apr;41(17):2444-2457
Oncogene 2022 Apr;41(17):2444-2457
Interleukin-17A mediates tobacco smoke-induced lung cancer epithelial-mesenchymal transition through transcriptional regulation of ΔNp63α on miR-19.
Xie C, Zhu J, Huang C, Yang X, Wang X, Meng Y, Geng S, Wu J, Shen H, Hu Z, Meng Z, Li X, Zhong C
Cell biology and toxicology 2022 Apr;38(2):273-289
Cell biology and toxicology 2022 Apr;38(2):273-289
MiR-125b enhances doxorubicin-induced cardiotoxicity by suppressing the nucleus-cytoplasmic translocation of YAP via targeting STARD13.
Jin X, Yu W, Ye P
Environmental toxicology 2022 Apr;37(4):730-740
Environmental toxicology 2022 Apr;37(4):730-740
UHRF1 shapes both the trophoblast invasion and decidual macrophage differentiation in early pregnancy.
Liu H, Wang LL, Xu QH, Wang J, Zhang YJ, Luo J, Liao AH
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Apr;36(4):e22247
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Apr;36(4):e22247
TIMP2 mediates endoplasmic reticulum stress contributing to sepsis-induced acute kidney injury.
Jiang N, Huang R, Zhang J, Xu D, Li T, Sun Z, Su L, Peng Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Apr;36(4):e22228
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Apr;36(4):e22228
The alleviative effect of flavonol-type Nrf2 activator rhamnazin from Physalis alkekengi L. var. franchetii (Mast.) Makino on pulmonary disorders.
Wu XY, Wang T, Hu HX, Zhang K, Zhao Y, Zhao BB, Lou HX, Wang XN, Shen T
Phytotherapy research : PTR 2022 Apr;36(4):1692-1707
Phytotherapy research : PTR 2022 Apr;36(4):1692-1707
FAK regulates cardiomyocyte mitochondrial fission and function through Drp1.
Chang YW, Song ZH, Chen CC
The FEBS journal 2022 Apr;289(7):1897-1910
The FEBS journal 2022 Apr;289(7):1897-1910
Occludin facilitates tumour angiogenesis in bladder cancer by regulating IL8/STAT3 through STAT4.
Yang F, Liu XQ, He JZ, Xian SP, Yang PF, Mai ZY, Li M, Liu Y, Zhang XD
Journal of cellular and molecular medicine 2022 Apr;26(8):2363-2376
Journal of cellular and molecular medicine 2022 Apr;26(8):2363-2376
Genetic instability of lung induced by carbon black nanoparticles is related with Plk1 signals changes.
Pei Z, Ning J, Zhang N, Zhang X, Zhang H, Zhang R
NanoImpact 2022 Apr;26:100400
NanoImpact 2022 Apr;26:100400
Molecular mechanism of the TGF‑β/Smad7 signaling pathway in ulcerative colitis.
Bai B, Li H, Han L, Mei Y, Hu C, Mei Q, Xu J, Liu X
Molecular medicine reports 2022 Apr;25(4)
Molecular medicine reports 2022 Apr;25(4)
Exosomes derived from the blood of patients with sepsis regulate apoptosis and aerobic glycolysis in human myocardial cells via the hsa‑miR‑1262/SLC2A1 signaling pathway.
Sun F, Geng H, Sun Y, Feng W, Tian T, Ye L, Lei M
Molecular medicine reports 2022 Apr;25(4)
Molecular medicine reports 2022 Apr;25(4)
USP5 promotes breast cancer cell proliferation and metastasis by stabilizing HIF2α.
Huang W, Liu X, Zhang Y, Deng M, Li G, Chen G, Yu L, Jin L, Liu T, Wang Y, Chen Y
Journal of cellular physiology 2022 Apr;237(4):2211-2219
Journal of cellular physiology 2022 Apr;237(4):2211-2219
UBE2T is upregulated, predicts poor prognosis, and promotes cell proliferation and invasion by promoting epithelial-mesenchymal transition via inhibiting autophagy in an AKT/mTOR dependent manner in ovarian cancer.
Huang W, Huang H, Xiao Y, Wang L, Zhang T, Fang X, Xia X
Cell cycle (Georgetown, Tex.) 2022 Apr;21(8):780-791
Cell cycle (Georgetown, Tex.) 2022 Apr;21(8):780-791
Itaconate attenuates osteoarthritis by inhibiting STING/NF-κB axis in chondrocytes and promoting M2 polarization in macrophages.
Ni L, Lin Z, Hu S, Shi Y, Jiang Z, Zhao J, Zhou Y, Wu Y, Tian N, Sun L, Wu A, Pan Z, Zhang X, Wang X
Biochemical pharmacology 2022 Apr;198:114935
Biochemical pharmacology 2022 Apr;198:114935
Pharmacological targeting macrophage phenotype via gut-kidney axis ameliorates renal fibrosis in mice.
Xie Y, Hu X, Li S, Qiu Y, Cao R, Xu C, Lu C, Wang Z, Yang J
Pharmacological research 2022 Apr;178:106161
Pharmacological research 2022 Apr;178:106161
Tetrastigma hemsleyanum Diels et Gilg ameliorates lipopolysaccharide induced sepsis via repairing the intestinal mucosal barrier.
Zhan L, Pu J, Zheng J, Hang S, Pang L, Dai M, Ji C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Apr;148:112741
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Apr;148:112741
circHIPK3 regulates cell proliferation and migration by sponging microRNA-124 and regulating serine/threonine kinase 3 expression in esophageal squamous cell carcinoma.
Yao D, Lin S, Chen S, Wang Z
Bioengineered 2022 Apr;13(4):9767-9780
Bioengineered 2022 Apr;13(4):9767-9780
Human umbilical vein endothelial cells-derived exosomes enhance cardiac function after acute myocardial infarction by activating the PI3K/AKT signaling pathway.
Liu W, Feng Y, Wang X, Ding J, Li H, Guan H, Chen Z
Bioengineered 2022 Apr;13(4):8850-8865
Bioengineered 2022 Apr;13(4):8850-8865
HSP90 promotes radioresistance of cervical cancer cells via reducing FBXO6-mediated CD147 polyubiquitination.
Song Q, Wen J, Li W, Xue J, Zhang Y, Liu H, Han J, Ning T, Lu Z
Cancer science 2022 Apr;113(4):1463-1474
Cancer science 2022 Apr;113(4):1463-1474
The OPG/RANKL/RANK system modulates calcification of common carotid artery in simulated microgravity rats by regulating NF-κB pathway.
Liu H, Ru NY, Cai Y, Lyu Q, Guo CH, Zhou Y, Li SH, Cheng JH, Chang JR, Ma J, Su XL
Canadian journal of physiology and pharmacology 2022 Apr;100(4):324-333
Canadian journal of physiology and pharmacology 2022 Apr;100(4):324-333
BRD4 promotes the migration and invasion of bladder cancer cells through the Sonic hedgehog signaling pathway and enhances cisplatin resistance.
Liu T, Zhang Z, Wang C, Huang H, Li Y
Biochemistry and cell biology = Biochimie et biologie cellulaire 2022 Apr;100(2):179-187
Biochemistry and cell biology = Biochimie et biologie cellulaire 2022 Apr;100(2):179-187
LATS1 is a central signal transmitter for achieving full type-I interferon activity.
Zuo Y, He J, Liu S, Xu Y, Liu J, Qiao C, Zang L, Sun W, Yuan Y, Zhang H, Chen X, Jin L, Miao Y, Huang F, Ren T, Wang J, Qian F, Zhu C, Zhang W, Liu Y, Xu G, Ma F, Zheng H
Science advances 2022 Apr 8;8(14):eabj3887
Science advances 2022 Apr 8;8(14):eabj3887
Mechanosensitive Piezo1 channels mediate renal fibrosis.
Zhao X, Kong Y, Liang B, Xu J, Lin Y, Zhou N, Li J, Jiang B, Cheng J, Li C, Wang W
JCI insight 2022 Apr 8;7(7)
JCI insight 2022 Apr 8;7(7)
Sp1 S-Sulfhydration Induced by Hydrogen Sulfide Inhibits Inflammation via HDAC6/MyD88/NF-κB Signaling Pathway in Adjuvant-Induced Arthritis.
Li M, Hu W, Wang R, Li Z, Yu Y, Zhuo Y, Zhang Y, Wang Z, Qiu Y, Chen K, Ding Q, Qi W, Zhu M, Zhu Y
Antioxidants (Basel, Switzerland) 2022 Apr 7;11(4)
Antioxidants (Basel, Switzerland) 2022 Apr 7;11(4)
Stearic Acid Activates the PI3K-mTOR-4EBP1/S6K and mTOR-SREBP-1 Signaling Axes through FATP4-CDK1 To Promote Milk Synthesis in Primary Bovine Mammary Epithelial Cells.
Li F, Hu G, Long X, Cao Y, Li Q, Guo W, Wang J, Liu J, Fu S
Journal of agricultural and food chemistry 2022 Apr 6;70(13):4007-4018
Journal of agricultural and food chemistry 2022 Apr 6;70(13):4007-4018
The Slack Channel Regulates Anxiety-Like Behaviors via Basolateral Amygdala Glutamatergic Projections to Ventral Hippocampus.
Zhang Q, Gao SH, Shen ZS, Wang Y, Hu SW, Duan GB, Liu Y, Zhong DY, Liu J, Sun MH, Zhang X, Cao TY, Cao JL, Tang QY, Zhang Z
The Journal of neuroscience : the official journal of the Society for Neuroscience 2022 Apr 6;42(14):3049-3064
The Journal of neuroscience : the official journal of the Society for Neuroscience 2022 Apr 6;42(14):3049-3064
METTL3-mediated m(6)A modification of TIMP2 mRNA promotes podocyte injury in diabetic nephropathy.
Jiang L, Liu X, Hu X, Gao L, Zeng H, Wang X, Huang Y, Zhu W, Wang J, Wen J, Meng X, Wu Y
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Apr 6;30(4):1721-1740
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Apr 6;30(4):1721-1740
TNFAIP8 protein functions as a tumor suppressor in inflammation-associated colorectal tumorigenesis.
Lou Y, Tian X, Sun C, Song M, Han M, Zhao Y, Song Y, Song X, Zhang W, Chen YH, Wang H
Cell death & disease 2022 Apr 6;13(4):311
Cell death & disease 2022 Apr 6;13(4):311
Pdcd4 promotes lipid deposition by attenuating PPARα-mediated fatty acid oxidation in hepatocytes.
Du X, Osoro EK, Chen Q, Yan X, Gao D, Wu L, Ren J, Feng L, Wu N, Lu K, Yang X, Zhong B, Han Y, Zhang F, Li D, Lan X, Lu S
Molecular and cellular endocrinology 2022 Apr 5;545:111562
Molecular and cellular endocrinology 2022 Apr 5;545:111562
Positive feedback regulation of microglial glucose metabolism by histone H4 lysine 12 lactylation in Alzheimer's disease.
Pan RY, He L, Zhang J, Liu X, Liao Y, Gao J, Liao Y, Yan Y, Li Q, Zhou X, Cheng J, Xing Q, Guan F, Zhang J, Sun L, Yuan Z
Cell metabolism 2022 Apr 5;34(4):634-648.e6
Cell metabolism 2022 Apr 5;34(4):634-648.e6
miR-AB, a miRNA-based shRNA viral toolkit for multicolor-barcoded multiplex RNAi at a single-cell level.
Wang D, Xiu J, Zhao J, Luo J
EMBO reports 2022 Apr 5;23(4):e53691
EMBO reports 2022 Apr 5;23(4):e53691
Vitamin K2 Modulates Mitochondrial Dysfunction Induced by 6-Hydroxydopamine in SH-SY5Y Cells via Mitochondrial Quality-Control Loop.
Tang H, Zheng Z, Wang H, Wang L, Zhao G, Wang P
Nutrients 2022 Apr 4;14(7)
Nutrients 2022 Apr 4;14(7)
Proteomic Analysis of Vero Cells Infected with Pseudorabies Virus.
Yang X, Xu S, Chen D, Jiang R, Kang H, Ge X, Zhou L, Han J, Zhang Y, Guo X, Yang H
Viruses 2022 Apr 4;14(4)
Viruses 2022 Apr 4;14(4)
Ginsenoside Rk1 regulates glutamine metabolism in hepatocellular carcinoma through inhibition of the ERK/c-Myc pathway.
Lu H, Yin H, Qu L, Ma X, Fu R, Fan D
Food & function 2022 Apr 4;13(7):3793-3811
Food & function 2022 Apr 4;13(7):3793-3811
Antioxidant Activity of Acanthopanax senticosus Flavonoids in H(2)O(2)-Induced RAW 264.7 Cells and DSS-Induced Colitis in Mice.
Su J, Zhang X, Kan Q, Chu X
Molecules (Basel, Switzerland) 2022 Apr 30;27(9)
Molecules (Basel, Switzerland) 2022 Apr 30;27(9)
LMOD1, an oncogene associated with Lauren classification, regulates the metastasis of gastric cancer cells through the FAK-AKT/mTOR pathway.
Tan Y, Chen Q, Pan S, An W, Xu H, Xing Y, Zhang J
BMC cancer 2022 Apr 30;22(1):474
BMC cancer 2022 Apr 30;22(1):474
Cdh1 Deficiency Sensitizes TNBC Cells to PARP Inhibitors.
Li J, Lan M, Peng J, Xiong Q, Xu Y, Yang Y, Zhou Y, Liu J, Zeng Z, Yang X, Zhang Z, Zhang P, Zhu Q, Wu W
Genes 2022 Apr 30;13(5)
Genes 2022 Apr 30;13(5)
Neuron-specific enolase promotes stem cell-like characteristics of small-cell lung cancer by downregulating NBL1 and activating the BMP2/Smad/ID1 pathway.
Lu L, Zha Z, Zhang P, Wang P, Liu X, Fang X, Weng C, Li B, Mao H, Wang L, Guan M, Wu Y, Xu Z, Liu Z, Liu G
Oncogenesis 2022 Apr 29;11(1):21
Oncogenesis 2022 Apr 29;11(1):21
Trappc9 Deficiency Impairs the Plasticity of Stem Cells.
Usman M, Li Y, Ke Y, Chhetri G, Islam MA, Wang Z, Li X
International journal of molecular sciences 2022 Apr 28;23(9)
International journal of molecular sciences 2022 Apr 28;23(9)
MicroRNA-146a-5p-modified human umbilical cord mesenchymal stem cells enhance protection against diabetic nephropathy in rats through facilitating M2 macrophage polarization.
Zhang Y, Le X, Zheng S, Zhang K, He J, Liu M, Tu C, Rao W, Du H, Ouyang Y, Li C, Wu D
Stem cell research & therapy 2022 Apr 27;13(1):171
Stem cell research & therapy 2022 Apr 27;13(1):171
Mandarin Fish (Siniperca chuatsi) p53 Regulates Glutaminolysis Induced by Virus via the p53/miR145-5p/c-Myc Pathway in Chinese Perch Brain Cells.
Ye C, Liu S, Li N, Zuo S, Niu Y, Lin Q, Liang H, Luo X, Fu X
Microbiology spectrum 2022 Apr 27;10(2):e0272721
Microbiology spectrum 2022 Apr 27;10(2):e0272721
Propofol protects against high glucose-mediated endothelial injury via inhibition of COX2 and iNOS expressions.
Shao J, Ding J, Lu L, Hou W, Wang F, Sun Z, Jiang H, Zhao Y
Acta biochimica et biophysica Sinica 2022 Apr 25;54(4):548-555
Acta biochimica et biophysica Sinica 2022 Apr 25;54(4):548-555
RETREG1-mediated ER-phagy activation induced by glucose deprivation alleviates nucleus pulposus cell damage via ER stress pathway.
Luo R, Liang H, Zhang W, Li G, Zhao K, Hua W, Song Y, Yang C
Acta biochimica et biophysica Sinica 2022 Apr 25;54(4):524-536
Acta biochimica et biophysica Sinica 2022 Apr 25;54(4):524-536
A methylprednisolone-loaded and core-shell nanofiber-covered stent-graft to prevent inflammation and reduce degradation in aortic dissection.
Liu J, Zhu H, Pei Y, Zhang H, Zhou J, Jing Z
Biomaterials research 2022 Apr 25;26(1):15
Biomaterials research 2022 Apr 25;26(1):15
Network pharmacology analysis and experimental validation to explore the mechanism of Shenlian extract on myocardial ischemia.
Li JJ, Wang CM, Wang YJ, Yang Q, Cai WY, Li YJ, Song M, Zang YL, Cui XH, Li Q, Chen Y, Weng XG, Zhu XX
Journal of ethnopharmacology 2022 Apr 24;288:114973
Journal of ethnopharmacology 2022 Apr 24;288:114973
Reversal of Lipid Metabolism Dysregulation by Selenium and Folic Acid Co-Supplementation to Mitigate Pathology in Alzheimer's Disease.
Zhang ZH, Cao XC, Peng JY, Huang SL, Chen C, Jia SZ, Ni JZ, Song GL
Antioxidants (Basel, Switzerland) 2022 Apr 24;11(5)
Antioxidants (Basel, Switzerland) 2022 Apr 24;11(5)
A novel oncogenic seRNA promotes nasopharyngeal carcinoma metastasis.
Tan Y, Jiang C, Jia Q, Wang J, Huang G, Tang F
Cell death & disease 2022 Apr 23;13(4):401
Cell death & disease 2022 Apr 23;13(4):401
Telomerase RNA TERC and the PI3K-AKT pathway form a positive feedback loop to regulate cell proliferation independent of telomerase activity.
Wu S, Ge Y, Lin K, Liu Q, Zhou H, Hu Q, Zhao Y, He W, Ju Z
Nucleic acids research 2022 Apr 22;50(7):3764-3776
Nucleic acids research 2022 Apr 22;50(7):3764-3776
ORP5 promotes tumor metastasis via stabilizing c-Met in renal cell carcinoma.
Song L, Zhang L, Zhou Y, Shao X, Xu Y, Pei D, Wang Q
Cell death discovery 2022 Apr 21;8(1):219
Cell death discovery 2022 Apr 21;8(1):219
Comparative Proteomic Analysis Reveals Mx1 Inhibits Senecavirus A Replication in PK-15 Cells by Interacting with the Capsid Proteins VP1, VP2 and VP3.
Gao H, Xiang Z, Ge X, Zhou L, Han J, Guo X, Chen Y, Zhang Y, Yang H
Viruses 2022 Apr 21;14(5)
Viruses 2022 Apr 21;14(5)
HGF/c-Met pathway facilitates the perineural invasion of pancreatic cancer by activating the mTOR/NGF axis.
Qin T, Xiao Y, Qian W, Wang X, Gong M, Wang Q, An R, Han L, Duan W, Ma Q, Wang Z
Cell death & disease 2022 Apr 21;13(4):387
Cell death & disease 2022 Apr 21;13(4):387
Oryzanol alleviates high fat and cholesterol diet-induced hypercholesterolemia associated with the modulation of the gut microbiota in hamsters.
Yan S, Chen J, Zhu L, Guo T, Qin D, Hu Z, Han S, Wang J, Matias FB, Wen L, Luo F, Lin Q
Food & function 2022 Apr 20;13(8):4486-4501
Food & function 2022 Apr 20;13(8):4486-4501
Age-dependent effects of a high-fat diet combined with dietary advanced glycation end products on cognitive function and protection with voluntary exercise.
Luo L, Li R, Wang G, Chen J, Chen L, Qin LQ, Yu Z, Wan Z
Food & function 2022 Apr 20;13(8):4445-4458
Food & function 2022 Apr 20;13(8):4445-4458
Exosomal miR-146a-5p and miR-155-5p promote CXCL12/CXCR7-induced metastasis of colorectal cancer by crosstalk with cancer-associated fibroblasts.
Wang D, Wang X, Song Y, Si M, Sun Y, Liu X, Cui S, Qu X, Yu X
Cell death & disease 2022 Apr 20;13(4):380
Cell death & disease 2022 Apr 20;13(4):380
Suppression of premature transcription termination leads to reduced mRNA isoform diversity and neurodegeneration.
LaForce GR, Farr JS, Liu J, Akesson C, Gumus E, Pinkard O, Miranda HC, Johnson K, Sweet TJ, Ji P, Lin A, Coller J, Philippidou P, Wagner EJ, Schaffer AE
Neuron 2022 Apr 20;110(8):1340-1357.e7
Neuron 2022 Apr 20;110(8):1340-1357.e7
TRIM26-mediated degradation of nucleocapsid protein limits porcine reproductive and respiratory syndrome virus-2 infection.
Zhao P, Jing H, Dong W, Duan E, Ke W, Tao R, Li Y, Cao S, Wang H, Zhang Y, Sun Y, Wang J
Virus research 2022 Apr 2;311:198690
Virus research 2022 Apr 2;311:198690
Graphene quantum dots rescue angiogenic retinopathy via blocking STAT3/Periostin/ERK signaling.
Zhao N, Gui X, Fang Q, Zhang R, Zhu W, Zhang H, Li Q, Zhou Y, Zhao J, Cui X, Gao G, Tang H, Shen N, Chen T, Song H, Shen W
Journal of nanobiotechnology 2022 Apr 2;20(1):174
Journal of nanobiotechnology 2022 Apr 2;20(1):174
Flubendazole induces mitochondrial dysfunction and DRP1-mediated mitophagy by targeting EVA1A in breast cancer.
Zhen Y, Yuan Z, Zhang J, Chen Y, Fu Y, Liu Y, Fu L, Zhang L, Zhou XL
Cell death & disease 2022 Apr 19;13(4):375
Cell death & disease 2022 Apr 19;13(4):375
Cavβ1 regulates T cell expansion and apoptosis independently of voltage-gated Ca(2+) channel function.
Erdogmus S, Concepcion AR, Yamashita M, Sidhu I, Tao AY, Li W, Rocha PP, Huang B, Garippa R, Lee B, Lee A, Hell JW, Lewis RS, Prakriya M, Feske S
Nature communications 2022 Apr 19;13(1):2033
Nature communications 2022 Apr 19;13(1):2033
Inhibition of KIF23 Alleviates IPAH by Targeting Pyroptosis and Proliferation of PASMCs.
Wu Z, Zhou G, Wang H, Yao P
International journal of molecular sciences 2022 Apr 18;23(8)
International journal of molecular sciences 2022 Apr 18;23(8)
Regulatory variants at 2q33.1 confer schizophrenia risk by modulating distal gene TYW5 expression.
Li S, Li J, Liu J, Wang J, Li X, Huo Y, Li Y, Liu Y, Li M, Xiao X, Luo XJ
Brain : a journal of neurology 2022 Apr 18;145(2):770-786
Brain : a journal of neurology 2022 Apr 18;145(2):770-786
β-catenin correlates with the progression of colon cancers and berberine inhibits the proliferation of colon cancer cells by regulating the β-catenin signaling pathway.
Nie Q, Peng WW, Wang Y, Zhong L, Zhang X, Zeng L
Gene 2022 Apr 15;818:146207
Gene 2022 Apr 15;818:146207
Identified human breast milk compositions effectively inhibit SARS-CoV-2 and variants infection and replication.
Lai X, Yu Y, Xian W, Ye F, Ju X, Luo Y, Dong H, Zhou YH, Tan W, Zhuang H, Li T, Liu X, Ding Q, Xiang K
iScience 2022 Apr 15;25(4):104136
iScience 2022 Apr 15;25(4):104136
VPS28 regulates brain vasculature by controlling neuronal VEGF trafficking through extracellular vesicle secretion.
Dong X, Jiang D, Wang L, Zhao J, Yu L, Huang Y, Wu X, Zhu Y, Zhao Y, Zhao Q, Zhang G, Li X
iScience 2022 Apr 15;25(4):104042
iScience 2022 Apr 15;25(4):104042
Xihuang pills induce apoptosis in hepatocellular carcinoma by suppressing phosphoinositide 3-kinase/protein kinase-B/mechanistic target of rapamycin pathway.
Teng YJ, Deng Z, Ouyang ZG, Zhou Q, Mei S, Fan XX, Wu YR, Long HP, Fang LY, Yin DL, Zhang BY, Guo YM, Zhu WH, Huang Z, Zheng P, Ning DM, Tian XF
World journal of gastrointestinal oncology 2022 Apr 15;14(4):872-886
World journal of gastrointestinal oncology 2022 Apr 15;14(4):872-886
EGFR/MET promotes hepatocellular carcinoma metastasis by stabilizing tumor cells and resisting to RTKs inhibitors in circulating tumor microemboli.
Song S, Yu Z, You Y, Liu C, Xie X, Lv H, Xiao F, Zhu Q, Qin C
Cell death & disease 2022 Apr 15;13(4):351
Cell death & disease 2022 Apr 15;13(4):351
Tumor-resident intracellular microbiota promotes metastatic colonization in breast cancer.
Fu A, Yao B, Dong T, Chen Y, Yao J, Liu Y, Li H, Bai H, Liu X, Zhang Y, Wang C, Guo Y, Li N, Cai S
Cell 2022 Apr 14;185(8):1356-1372.e26
Cell 2022 Apr 14;185(8):1356-1372.e26
miR-199-5p regulates spermiogenesis at the posttranscriptional level via targeting Tekt1 in allotriploid crucian carp.
Li S, Wang Q, Huang L, Fan S, Li T, Shu Y, Zhang C, Zhou Y, Liu Q, Luo K, Tao M, Liu S
Journal of animal science and biotechnology 2022 Apr 13;13(1):44
Journal of animal science and biotechnology 2022 Apr 13;13(1):44
Intestinal Tuft-2 cells exert antimicrobial immunity via sensing bacterial metabolite N-undecanoylglycine.
Xiong Z, Zhu X, Geng J, Xu Y, Wu R, Li C, Fan D, Qin X, Du Y, Tian Y, Fan Z
Immunity 2022 Apr 12;55(4):686-700.e7
Immunity 2022 Apr 12;55(4):686-700.e7
An oxygen-adaptive interaction between SNHG12 and occludin maintains blood-brain barrier integrity.
Li Y, Wei JY, Liu H, Wang KJ, Jin SN, Su ZK, Wang HJ, Shi JX, Li B, Shang DS, Fang WG, Qin XX, Zhao WD, Chen YH
Cell reports 2022 Apr 12;39(2):110656
Cell reports 2022 Apr 12;39(2):110656
Dapagliflozin, sildenafil and their combination in monocrotaline-induced pulmonary arterial hypertension.
Tang Y, Tan S, Li M, Tang Y, Xu X, Zhang Q, Fu Q, Tang M, He J, Zhang Y, Zheng Z, Peng J, Zhu T, Xie W
BMC pulmonary medicine 2022 Apr 12;22(1):142
BMC pulmonary medicine 2022 Apr 12;22(1):142
Proteomic Studies of the Mechanism of Cytotoxicity, Induced by Palytoxin on HaCaT Cells.
Cheng D, Deng B, Tong Q, Gao S, Xiao B, Zhu M, Ren Z, Wang L, Sun M
Toxins 2022 Apr 10;14(4)
Toxins 2022 Apr 10;14(4)
Chidamide and mitomycin C exert synergistic cytotoxic effects against bladder cancer cells in vitro and suppress tumor growth in a rat bladder cancer model.
Wang SC, Yu CY, Wu YC, Chang YC, Chen SL, Sung WW
Cancer letters 2022 Apr 1;530:8-15
Cancer letters 2022 Apr 1;530:8-15
Microcystin-leucine arginine (MC-LR) induces mouse ovarian inflammation by promoting granulosa cells to produce inflammatory cytokine via activation of cGAS-STING signaling.
Liu K, Zhao X, Guo M, Zhu J, Li D, Ding J, Han X, Wu J
Toxicology letters 2022 Apr 1;358:6-16
Toxicology letters 2022 Apr 1;358:6-16
Norcantharidin Induces Immunogenic Cell Death of Bladder Cancer Cells through Promoting Autophagy in Acidic Culture.
Xu L, Su B, Mo L, Zhao C, Zhao Z, Li H, Hu Z, Li J
International journal of molecular sciences 2022 Apr 1;23(7)
International journal of molecular sciences 2022 Apr 1;23(7)
Urolithin A promotes mitophagy and suppresses NLRP3 inflammasome activation in lipopolysaccharide-induced BV2 microglial cells and MPTP-induced Parkinson's disease model.
Qiu J, Chen Y, Zhuo J, Zhang L, Liu J, Wang B, Sun D, Yu S, Lou H
Neuropharmacology 2022 Apr 1;207:108963
Neuropharmacology 2022 Apr 1;207:108963
Golgi Phosphoprotein 3 Confers Radioresistance via Stabilizing EGFR in Lung Adenocarcinoma.
Chen G, Kong P, Yang M, Hu W, Prise KM, Yu KN, Cui S, Qin F, Meng G, Almahi WA, Nie L, Han W
International journal of radiation oncology, biology, physics 2022 Apr 1;112(5):1216-1228
International journal of radiation oncology, biology, physics 2022 Apr 1;112(5):1216-1228
Inhibiting Hyper-O-GlcNAcylation of c-Myc accelerate diabetic wound healing by alleviating keratinocyte dysfunction.
Zhang J, Yang P, Liu D, Gao M, Wang J, Yu T, Zhang X, Liu Y
Burns & trauma 2021;9:tkab031
Burns & trauma 2021;9:tkab031
Comprehensive analysis of abnormal expression, prognostic value and oncogenic role of the hub gene FN1 in pancreatic ductal adenocarcinoma via bioinformatic analysis and in vitro experiments.
Lei X, Chen G, Li J, Wen W, Gong J, Fu J
PeerJ 2021;9:e12141
PeerJ 2021;9:e12141
Identification of KIF4A as a pan-cancer diagnostic and prognostic biomarker via bioinformatics analysis and validation in osteosarcoma cell lines.
Pan J, Lei X, Mao X
PeerJ 2021;9:e11455
PeerJ 2021;9:e11455
Integrated Analysis of Ferroptosis-Related Biomarker Signatures to Improve the Diagnosis and Prognosis Prediction of Ovarian Cancer.
Wang H, Cheng Q, Chang K, Bao L, Yi X
Frontiers in cell and developmental biology 2021;9:807862
Frontiers in cell and developmental biology 2021;9:807862
Identification and Validation of HOTAIRM1 as a Novel Biomarker for Oral Squamous Cell Carcinoma.
Yu Y, Niu J, Zhang X, Wang X, Song H, Liu Y, Jiao X, Chen F
Frontiers in bioengineering and biotechnology 2021;9:798584
Frontiers in bioengineering and biotechnology 2021;9:798584
Differential Expression Profiles and Potential Intergenerational Functions of tRNA-Derived Small RNAs in Mice After Cadmium Exposure.
Zeng L, Zhou J, Zhang Y, Wang X, Wang M, Su P
Frontiers in cell and developmental biology 2021;9:791784
Frontiers in cell and developmental biology 2021;9:791784
Exosomal MIF Derived From Nasopharyngeal Carcinoma Promotes Metastasis by Repressing Ferroptosis of Macrophages.
Chen W, Zuo F, Zhang K, Xia T, Lei W, Zhang Z, Bao L, You Y
Frontiers in cell and developmental biology 2021;9:791187
Frontiers in cell and developmental biology 2021;9:791187
PPy@Fe(3)O(4) Nanoparticles Inhibit Tumor Growth and Metastasis Through Chemodynamic and Photothermal Therapy in Non-small Cell Lung Cancer.
Fang D, Jin H, Huang X, Shi Y, Liu Z, Ben S
Frontiers in chemistry 2021;9:789934
Frontiers in chemistry 2021;9:789934
Keratin 17 Is Required for Lipid Metabolism in Keratinocytes and Benefits Epidermal Permeability Barrier Homeostasis.
Pang B, Zhu Z, Xiao C, Luo Y, Fang H, Bai Y, Sun Z, Ma J, Dang E, Wang G
Frontiers in cell and developmental biology 2021;9:779257
Frontiers in cell and developmental biology 2021;9:779257
Cadherin-12 Regulates Neurite Outgrowth Through the PKA/Rac1/Cdc42 Pathway in Cortical Neurons.
Guo B, Qi M, Huang S, Zhuo R, Zhang W, Zhang Y, Xu M, Liu M, Guan T, Liu Y
Frontiers in cell and developmental biology 2021;9:768970
Frontiers in cell and developmental biology 2021;9:768970
Multiple DSB Resection Activities Redundantly Promote Alternative End Joining-Mediated Class Switch Recombination.
Sun X, Bai J, Xu J, Xi X, Gu M, Zhu C, Xue H, Chen C, Dong J
Frontiers in cell and developmental biology 2021;9:767624
Frontiers in cell and developmental biology 2021;9:767624
TGR5 Activation Ameliorates Mitochondrial Homeostasis via Regulating the PKCδ/Drp1-HK2 Signaling in Diabetic Retinopathy.
Zhang MY, Zhu L, Zheng X, Xie TH, Wang W, Zou J, Li Y, Li HY, Cai J, Gu S, Yao Y, Wei TT
Frontiers in cell and developmental biology 2021;9:759421
Frontiers in cell and developmental biology 2021;9:759421
LncRNA FEZF1-AS1 Promotes Multi-Drug Resistance of Gastric Cancer Cells via Upregulating ATG5.
Gui Z, Zhao Z, Sun Q, Shao G, Huang J, Zhao W, Kuang Y
Frontiers in cell and developmental biology 2021;9:749129
Frontiers in cell and developmental biology 2021;9:749129
Eicosapentaenoic Acid-Induced Autophagy Attenuates Intervertebral Disc Degeneration by Suppressing Endoplasmic Reticulum Stress, Extracellular Matrix Degradation, and Apoptosis.
Lin Z, Ni L, Teng C, Zhang Z, Wu L, Jin Y, Lu X, Lin Z
Frontiers in cell and developmental biology 2021;9:745621
Frontiers in cell and developmental biology 2021;9:745621
Autophagy Regulates VDAC3 Ubiquitination by FBXW7 to Promote Erastin-Induced Ferroptosis in Acute Lymphoblastic Leukemia.
Zhu T, Liu B, Wu D, Xu G, Fan Y
Frontiers in cell and developmental biology 2021;9:740884
Frontiers in cell and developmental biology 2021;9:740884
TMT-Based Proteomic Explores the Influence of DHEA on the Osteogenic Differentiation of hBMSCs.
Liang X, He M, Zhu B, Zhu Y, He X, Liu D, Wei Q
Frontiers in cell and developmental biology 2021;9:726549
Frontiers in cell and developmental biology 2021;9:726549
Lack of MOF Decreases Susceptibility to Hypoxia and Promotes Multidrug Resistance in Hepatocellular Carcinoma via HIF-1α.
Wang M, Liu H, Zhang X, Zhao W, Lin X, Zhang F, Li D, Xu C, Xie F, Wu Z, Yang Q, Li X
Frontiers in cell and developmental biology 2021;9:718707
Frontiers in cell and developmental biology 2021;9:718707
ESRRB Facilitates the Conversion of Trophoblast-Like Stem Cells From Induced Pluripotent Stem Cells by Directly Regulating CDX2.
Yu S, Zhang R, Shen Q, Zhu Z, Zhang J, Wu X, Zhao W, Li N, Yang F, Wei H, Hua J
Frontiers in cell and developmental biology 2021;9:712224
Frontiers in cell and developmental biology 2021;9:712224
Role of GRK2 in Trophoblast Necroptosis and Spiral Artery Remodeling: Implications for Preeclampsia Pathogenesis.
Lv Z, Xiong LL, Qin X, Zhang H, Luo X, Peng W, Kilby MD, Saffery R, Baker PN, Qi HB
Frontiers in cell and developmental biology 2021;9:694261
Frontiers in cell and developmental biology 2021;9:694261
Cardioprotective Role of SIRT5 in Response to Acute Ischemia Through a Novel Liver-Cardiac Crosstalk Mechanism.
Zhou B, Xiao M, Hu H, Pei X, Xue Y, Miao G, Wang J, Li W, Du Y, Zhang P, Wei T
Frontiers in cell and developmental biology 2021;9:687559
Frontiers in cell and developmental biology 2021;9:687559
Cyclophosphamide Exposure Causes Long-Term Detrimental Effect of Oocytes Developmental Competence Through Affecting the Epigenetic Modification and Maternal Factors' Transcription During Oocyte Growth.
Yang W, Ma Y, Jin J, Ren P, Zhou H, Xu S, Zhang Y, Hu Z, Rong Y, Dai Y, Zhang Y, Zhang S
Frontiers in cell and developmental biology 2021;9:682060
Frontiers in cell and developmental biology 2021;9:682060
The E3 Ligase PIAS1 Regulates p53 Sumoylation to Control Stress-Induced Apoptosis of Lens Epithelial Cells Through the Proapoptotic Regulator Bax.
Nie Q, Chen H, Zou M, Wang L, Hou M, Xiang JW, Luo Z, Gong XD, Fu JL, Wang Y, Zheng SY, Xiao Y, Gan YW, Gao Q, Bai YY, Wang JM, Zhang L, Tang XC, Hu X, Gong L, Liu Y, Li DW
Frontiers in cell and developmental biology 2021;9:660494
Frontiers in cell and developmental biology 2021;9:660494
SARS-CoV-2 Host Receptor ACE2 Protein Expression Atlas in Human Gastrointestinal Tract.
An X, Lin W, Liu H, Zhong W, Zhang X, Zhu Y, Wang X, Li J, Sheng Q
Frontiers in cell and developmental biology 2021;9:659809
Frontiers in cell and developmental biology 2021;9:659809
MYC Enhances Cholesterol Biosynthesis and Supports Cell Proliferation Through SQLE.
Yang F, Kou J, Liu Z, Li W, Du W
Frontiers in cell and developmental biology 2021;9:655889
Frontiers in cell and developmental biology 2021;9:655889
NTNG1 Modulates Cisplatin Resistance in Epithelial Ovarian Cancer Cells via the GAS6/AXL/Akt Pathway.
Fang S, Luo Y, Zhang Y, Wang H, Liu Q, Li X, Yu T
Frontiers in cell and developmental biology 2021;9:652325
Frontiers in cell and developmental biology 2021;9:652325
TAp63α Is Involved in Tobacco Smoke-Induced Lung Cancer EMT and the Anti-cancer Activity of Curcumin via miR-19 Transcriptional Suppression.
Xie C, Zhu J, Yang X, Huang C, Zhou L, Meng Z, Li X, Zhong C
Frontiers in cell and developmental biology 2021;9:645402
Frontiers in cell and developmental biology 2021;9:645402
Grb2 Induces Cardiorenal Syndrome Type 3: Roles of IL-6, Cardiomyocyte Bioenergetics, and Akt/mTOR Pathway.
Wang J, Sun X, Wang X, Cui S, Liu R, Liu J, Fu B, Gong M, Wang C, Shi Y, Chen Q, Cai G, Chen X
Frontiers in cell and developmental biology 2021;9:630412
Frontiers in cell and developmental biology 2021;9:630412
Deficiency of Sirtuin 1 Impedes Endometrial Decidualization in Recurrent Implantation Failure Patients.
Li J, Qi J, Yao G, Zhu Q, Li X, Xu R, Zhu Z, Zhao H, Wang Y, Ding Y, Sun Y
Frontiers in cell and developmental biology 2021;9:598364
Frontiers in cell and developmental biology 2021;9:598364
The Cancer-Testis Long Non-coding RNA PCAT6 Facilitates the Malignant Phenotype of Ovarian Cancer by Sponging miR-143-3p.
Tan X, Shao Y, Teng Y, Liu S, Li W, Xue L, Cao Y, Sun C, Zhang J, Han J, Wu X, Xu H, Xie K
Frontiers in cell and developmental biology 2021;9:593677
Frontiers in cell and developmental biology 2021;9:593677
Zirconia Nanoparticles Induce HeLa Cell Death Through Mitochondrial Apoptosis and Autophagy Pathways Mediated by ROS.
Shang Y, Wang Q, Li J, Liu H, Zhao Q, Huang X, Dong H, Chen W, Gui R, Nie X
Frontiers in chemistry 2021;9:522708
Frontiers in chemistry 2021;9:522708
Inhibition of miR-96-5p May Reduce Aβ42/Aβ40 Ratio via Regulating ATP-binding cassette transporter A1.
Zhu M, Jia L, Jia J
Journal of Alzheimer's disease : JAD 2021;83(1):367-377
Journal of Alzheimer's disease : JAD 2021;83(1):367-377
Honokiol Restores Microglial Phagocytosis by Reversing Metabolic Reprogramming.
Li W, Wang S, Zhang H, Li B, Xu L, Li Y, Kong C, Jiao H, Wang Y, Pang Y, Qin W, Jia L, Jia J
Journal of Alzheimer's disease : JAD 2021;82(4):1475-1485
Journal of Alzheimer's disease : JAD 2021;82(4):1475-1485
JMJD1A/NR4A1 Signaling Regulates the Procession of Renal Tubular Epithelial Interstitial Fibrosis Induced by AGEs in HK-2.
Wang S, Zuo A, Jiang W, Xie J, Lin H, Sun W, Zhao M, Xia J, Shao J, Zhao X, Liang D, Yang A, Sun J, Wang M
Frontiers in medicine 2021;8:807694
Frontiers in medicine 2021;8:807694
A Global Phosphorylation Atlas of Proteins Within Pathological Site of Rotator Cuff Tendinopathy.
Wang Y, Zhang J, Lin Y, Cheng S, Wang D, Rao M, Jiang Y, Huang X, Chen R, Xie Y, Yin P, Cheng B
Frontiers in molecular biosciences 2021;8:787008
Frontiers in molecular biosciences 2021;8:787008
Lanthanum Chloride Sensitizes Cisplatin Resistance of Ovarian Cancer Cells via PI3K/Akt Pathway.
Fang S, Zhang P, Chen X, Liu F, Wang F
Frontiers in medicine 2021;8:776876
Frontiers in medicine 2021;8:776876
Auranofin and ICG-001 Emerge Synergistic Anti-tumor Effect on Canine Breast Cancer by Inducing Apoptosis via Mitochondrial Pathway.
Lin Z, Lin Z, Zhao Y, Cheng N, Zhang D, Lin J, Zhang H, Lin D
Frontiers in veterinary science 2021;8:772687
Frontiers in veterinary science 2021;8:772687
Maslinic Acid Attenuates Ischemia/Reperfusion Injury-Induced Myocardial Inflammation and Apoptosis by Regulating HMGB1-TLR4 Axis.
Li Q, Xu M, Li Z, Li T, Wang Y, Chen Q, Wang Y, Feng J, Yin X, Lu C
Frontiers in cardiovascular medicine 2021;8:768947
Frontiers in cardiovascular medicine 2021;8:768947
Spermidine Affects Cardiac Function in Heart Failure Mice by Influencing the Gut Microbiota and Cardiac Galectin-3.
Chen Y, Guo Z, Li S, Liu Z, Chen P
Frontiers in cardiovascular medicine 2021;8:765591
Frontiers in cardiovascular medicine 2021;8:765591
Loss of Hepatic Surf4 Depletes Lipid Droplets in the Adrenal Cortex but Does Not Impair Adrenal Hormone Production.
Chang X, Zhao Y, Qin S, Wang H, Wang B, Zhai L, Liu B, Gu HM, Zhang DW
Frontiers in cardiovascular medicine 2021;8:764024
Frontiers in cardiovascular medicine 2021;8:764024
S-Propargyl-Cysteine Attenuates Diabetic Cardiomyopathy in db/db Mice Through Activation of Cardiac Insulin Receptor Signaling.
Li Y, Xie KF, Chang YH, Wang C, Chen Y, Wang MJ, Zhu YC
Frontiers in cardiovascular medicine 2021;8:737191
Frontiers in cardiovascular medicine 2021;8:737191
The Regulation of Staphylococcus aureus-Induced Inflammatory Responses in Bovine Mammary Epithelial Cells.
Cai M, Fan W, Li X, Sun H, Dai L, Lei D, Dai Y, Liao Y
Frontiers in veterinary science 2021;8:683886
Frontiers in veterinary science 2021;8:683886
β-Sitosterol Ameliorates Endometrium Receptivity in PCOS-Like Mice: The Mediation of Gut Microbiota.
Yu Y, Cao Y, Huang W, Liu Y, Lu Y, Zhao J
Frontiers in nutrition 2021;8:667130
Frontiers in nutrition 2021;8:667130
Exosomal MicroRNA-181a Derived From Mesenchymal Stem Cells Improves Gut Microbiota Composition, Barrier Function, and Inflammatory Status in an Experimental Colitis Model.
Gu L, Ren F, Fang X, Yuan L, Liu G, Wang S
Frontiers in medicine 2021;8:660614
Frontiers in medicine 2021;8:660614
Liraglutide Protects Nucleus Pulposus Cells Against High-Glucose Induced Apoptosis by Activating PI3K/Akt/ mTOR/Caspase-3 and PI3K/Akt/GSK3β/Caspase-3 Signaling Pathways.
Yao M, Zhang J, Li Z, Bai X, Ma J, Li Y
Frontiers in medicine 2021;8:630962
Frontiers in medicine 2021;8:630962
Identification of the Prognostic Value Among Suppressor Of Cytokine Signaling Family Members in Kidney Renal Clear Cell Carcinoma.
Li C, Zhang W, Fang T, Li N, Wang Y, He L, He H
Frontiers in molecular biosciences 2021;8:585000
Frontiers in molecular biosciences 2021;8:585000
Hydroxysafflor yellow A acutely attenuates blood-brain barrier permeability, oxidative stress, inflammation and apoptosis in traumatic brain injury in rats1.
Xu J, Zhan T, Zheng W, Huang YK, Chen K, Zhang XH, Ren P, Huang X
Acta cirurgica brasileira 2021;35(12):e351202
Acta cirurgica brasileira 2021;35(12):e351202
Autophagy Prevents Osteocyte Cell Death under Hypoxic Conditions.
Kurihara M, Mukudai Y, Watanabe H, Asakura M, Abe Y, Houri A, Chikuda J, Shimane T, Shirota T
Cells, tissues, organs 2021;210(5-6):326-338
Cells, tissues, organs 2021;210(5-6):326-338
Long Noncoding RNA HCG9 Promotes Osteosarcoma Progression through RAD51 by Acting as a ceRNA of miR-34b-3p.
Wang L, Li S, Qi L, Ling L
Mediators of inflammation 2021;2021:9978882
Mediators of inflammation 2021;2021:9978882
Exosomes Containing LINC00636 Inhibit MAPK1 through the miR-450a-2-3p Overexpression in Human Pericardial Fluid and Improve Cardiac Fibrosis in Patients with Atrial Fibrillation.
Liu L, Luo F, Lei K
Mediators of inflammation 2021;2021:9960241
Mediators of inflammation 2021;2021:9960241
TRIM29 Reverses Oxaliplatin Resistance of P53 Mutant Colon Cancer Cell.
Lei G, Liu S, Yang X, He C
Canadian journal of gastroenterology & hepatology 2021;2021:8870907
Canadian journal of gastroenterology & hepatology 2021;2021:8870907
Constitutive Androstane Receptor-Mediated Inhibition of Metformin on Phase II Metabolic Enzyme SULT2A1.
Hu X, Li M, Zhang C, Pang S
International journal of endocrinology 2021;2021:8867218
International journal of endocrinology 2021;2021:8867218
Ze-Qi-Tang Formula Induces Granulocytic Myeloid-Derived Suppressor Cell Apoptosis via STAT3/S100A9/Bcl-2/Caspase-3 Signaling to Prolong the Survival of Mice with Orthotopic Lung Cancer.
Xu ZH, Zhu YZ, Su L, Tang XY, Yao C, Jiao XN, Hou YF, Chen X, Wei LY, Wang WT, Wang J, Gong CY, Zhu XD, Zhang F, Zhu SG, Zou CP
Mediators of inflammation 2021;2021:8856326
Mediators of inflammation 2021;2021:8856326
ADAM17 Mediates Hypoxia-Induced Keratinocyte Migration via the p38/MAPK Pathway.
Zhu G, Liu J, Wang Y, Jia N, Wang W, Zhang J, Liang Y, Tian H, Zhang J
BioMed research international 2021;2021:8328216
BioMed research international 2021;2021:8328216
Tanshinone I Mitigates Steroid-Induced Osteonecrosis of the Femoral Head and Activates the Nrf2 Signaling Pathway in Rats.
Xu X, Shen Y, Lv H, Zhao J, Li X, Gao L, Ren S, Zhang X
Evidence-based complementary and alternative medicine : eCAM 2021;2021:8002161
Evidence-based complementary and alternative medicine : eCAM 2021;2021:8002161
Catalpol-Induced AMPK Activation Alleviates Cisplatin-Induced Nephrotoxicity through the Mitochondrial-Dependent Pathway without Compromising Its Anticancer Properties.
Zhang J, Zhao T, Wang C, Meng Q, Huo X, Wang C, Sun P, Sun H, Ma X, Wu J, Liu K
Oxidative medicine and cellular longevity 2021;2021:7467156
Oxidative medicine and cellular longevity 2021;2021:7467156
In Hepatocellular Carcinoma, miRNA-296-3p Targets MSL2 and Suppresses Cell Proliferation and Invasion.
Li X, An M, Gao Z
Journal of oncology 2021;2021:7430468
Journal of oncology 2021;2021:7430468
UBC Mediated by SEPT6 Inhibited the Progression of Prostate Cancer.
Zhang R, Yang Y, Huang H, Li T, Ye L, Lin L, Wei Y
Mediators of inflammation 2021;2021:7393029
Mediators of inflammation 2021;2021:7393029
High Methionine Diet-Induced Alzheimer's Disease like Symptoms Are Accompanied by 5-Methylcytosine Elevated Levels in the Brain.
Pi T, Wei S, Jiang Y, Shi JS
Behavioural neurology 2021;2021:6683318
Behavioural neurology 2021;2021:6683318
Neferine Protects against Hypoxic-Ischemic Brain Damage in Neonatal Rats by Suppressing NLRP3-Mediated Inflammasome Activation.
Zhu JJ, Yu BY, Huang XK, He MZ, Chen BW, Chen TT, Fang HY, Chen SQ, Fu XQ, Li PJ, Lin ZL, Zhu JH
Oxidative medicine and cellular longevity 2021;2021:6654954
Oxidative medicine and cellular longevity 2021;2021:6654954
The Regulation of ROS- and BECN1-Mediated Autophagy by Human Telomerase Reverse Transcriptase in Glioblastoma.
Ding X, Nie Z, She Z, Bai X, Yang Q, Wang F, Wang F, Geng X
Oxidative medicine and cellular longevity 2021;2021:6636510
Oxidative medicine and cellular longevity 2021;2021:6636510
Overexpression of RIPK4 Predicts Poor Prognosis and Promotes Metastasis in Ovarian Cancer.
Liu S, He L, Sheng C, Su R, Wu X, Sun Y, Xi X
BioMed research international 2021;2021:6622439
BioMed research international 2021;2021:6622439
Uncovering the Pharmacology of Xiaochaihu Decoction in the Treatment of Acute Pancreatitis Based on the Network Pharmacology.
Zhan L, Pu J, Hu Y, Xu P, Liang W, Ji C
BioMed research international 2021;2021:6621682
BioMed research international 2021;2021:6621682
Taohong Siwu-Containing Serum Enhances Angiogenesis in Rat Aortic Endothelial Cells by Regulating the VHL/HIF-1α/VEGF Signaling Pathway.
Tang Z, Li W, Xie H, Jiang S, Pu Y, Xiong H
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6610116
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6610116
GDF-15 Suppresses Atherosclerosis by Inhibiting oxLDL-Induced Lipid Accumulation and Inflammation in Macrophages.
Huang H, Chen Z, Li Y, Gong K, Xiao L, Fu H, Yang J, Wang X, Meng Q
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6497568
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6497568
Deficiency of MIF Accentuates Overloaded Compression-Induced Nucleus Pulposus Cell Oxidative Damage via Depressing Mitophagy.
Wang Y, Hu Y, Wang H, Liu N, Luo L, Zhao C, Zhou D, Tong H, Li P, Zhou Q
Oxidative medicine and cellular longevity 2021;2021:6192498
Oxidative medicine and cellular longevity 2021;2021:6192498
Epigallocatechin-3-Gallate Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease via Inhibition of Apoptosis and Promotion of Autophagy through the ROS/MAPK Signaling Pathway.
Wu D, Liu Z, Wang Y, Zhang Q, Li J, Zhong P, Xie Z, Ji A, Li Y
Oxidative medicine and cellular longevity 2021;2021:5599997
Oxidative medicine and cellular longevity 2021;2021:5599997
EZH2 Mediates miR-146a-5p/HIF-1α to Alleviate Inflammation and Glycolysis after Acute Spinal Cord Injury.
Ni S, Yang B, Xia L, Zhang H
Mediators of inflammation 2021;2021:5591582
Mediators of inflammation 2021;2021:5591582
A Network Pharmacology Approach for Exploring the Mechanisms of Panax notoginseng Saponins in Ischaemic Stroke.
Wang C, Chen H, Ma ST, Mao BB, Chen Y, Xu HN, Yu H
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5582782
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5582782
Inhibition of α-Synuclein Accumulation Improves Neuronal Apoptosis and Delayed Postoperative Cognitive Recovery in Aged Mice.
Li Y, Yuan Y, Li Y, Han D, Liu T, Yang N, Mi X, Hong J, Liu K, Song Y, He J, Zhou Y, Han Y, Shi C, Yu S, Zou P, Guo X, Li Z
Oxidative medicine and cellular longevity 2021;2021:5572899
Oxidative medicine and cellular longevity 2021;2021:5572899
POU2F1 Promotes Cell Viability and Tumor Growth in Gastric Cancer through Transcriptional Activation of lncRNA TTC3-AS1.
Wang J, Xiao K, Hou F, Tang L, Luo D, Liu G, Wang Z
Journal of oncology 2021;2021:5570088
Journal of oncology 2021;2021:5570088
Baihe Jizihuang Tang Ameliorates Chronic Unpredictable Mild Stress-Induced Depression-Like Behavior: Integrating Network Pharmacology and Brain-Gut Axis Evaluation.
Zhu JP, Wu HY, Zi Y, Xia XB, Xie MZ, Yuan ZY
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5554363
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5554363
NOX4-Derived ROS Mediates TGF-β1-Induced Metabolic Reprogramming during Epithelial-Mesenchymal Transition through the PI3K/AKT/HIF-1α Pathway in Glioblastoma.
Su X, Yang Y, Guo C, Zhang R, Sun S, Wang Y, Qiao Q, Fu Y, Pang Q
Oxidative medicine and cellular longevity 2021;2021:5549047
Oxidative medicine and cellular longevity 2021;2021:5549047
Study on the Antitumor Effect and Glycolysis of Andrographolide in Anaplastic Thyroid Carcinoma.
Yang K, Wu K, Feng J, Yutian L, Zhu X, Xu D
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5526581
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5526581
Berbamine Inhibits Cell Proliferation and Migration and Induces Cell Death of Lung Cancer Cells via Regulating c-Maf, PI3K/Akt, and MDM2-P53 Pathways.
Liu L, Xu Z, Yu B, Tao L, Cao Y
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5517143
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5517143
The Key Ingredient Acacetin in Weishu Decoction Alleviates Gastrointestinal Motility Disorder Based on Network Pharmacology Analysis.
Guo X, Xu Y, Tan HL, Wang XJ, Xiao L
Mediators of inflammation 2021;2021:5265444
Mediators of inflammation 2021;2021:5265444
The Effect of miR-520b on Macrophage Polarization and T Cell Immunity by Targeting PTEN in Breast Cancer.
Zhu Q, Yuan J, He Y, Hu Y
Journal of oncology 2021;2021:5170496
Journal of oncology 2021;2021:5170496
OM-MSCs Alleviate the Golgi Apparatus Stress Response following Cerebral Ischemia/Reperfusion Injury via the PEDF-PI3K/Akt/mTOR Signaling Pathway.
He J, Liu J, Huang Y, Tang X, Xiao H, Liu Z, Jiang Z, Zeng L, Hu Z, Lu M
Oxidative medicine and cellular longevity 2021;2021:4805040
Oxidative medicine and cellular longevity 2021;2021:4805040
The Dietary Supplement γ-Oryzanol Attenuates Hepatic Ischemia Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress and HMGB1/NLRP3 Inflammasome.
Du Y, Zhong F, Cheng H, Li T, Chen Y, Tan P, Huang M, Liang T, Liu Y, Xia X, Fu W
Oxidative medicine and cellular longevity 2021;2021:4628050
Oxidative medicine and cellular longevity 2021;2021:4628050
Ameliorative Effects and Mechanism of Buyang Huanwu Decoction on Pulmonary Vascular Remodeling: Network and Experimental Analyses.
Chen Y, Cui L, Wang C, Liu J, Guo J
Oxidative medicine and cellular longevity 2021;2021:4576071
Oxidative medicine and cellular longevity 2021;2021:4576071
Comparative Efficacy of Haizao Yuhu Decoction Composed of Different Varieties of Glycyrrhiza in Goiter Rats.
Chen F, Li N, Xiu L, Liu H, Chen S, He C, Fan A, Yu X, Wang X, Ge C, Huo M, He J, Zhong G
Evidence-based complementary and alternative medicine : eCAM 2021;2021:4343239
Evidence-based complementary and alternative medicine : eCAM 2021;2021:4343239
Zinc Regulates Glucose Metabolism of the Spinal Cord and Neurons and Promotes Functional Recovery after Spinal Cord Injury through the AMPK Signaling Pathway.
Hu H, Xia N, Lin J, Li D, Zhang C, Ge M, Tian H, Mei X
Oxidative medicine and cellular longevity 2021;2021:4331625
Oxidative medicine and cellular longevity 2021;2021:4331625
ARHGAP11A Promotes the Malignant Progression of Gastric Cancer by Regulating the Stability of Actin Filaments through TPM1.
Guan X, Guan X, Qin J, Qin L, Shi W, Jiao Z
Journal of oncology 2021;2021:4146910
Journal of oncology 2021;2021:4146910
Nrf2 Pathway Ameliorates Bladder Dysfunction in Cyclophosphamide-Induced Cystitis via Suppression of Oxidative Stress.
Ni B, Chen Z, Shu L, Shao Y, Huang Y, Tamrat NE, Wei Z, Shen B
Oxidative medicine and cellular longevity 2021;2021:4009308
Oxidative medicine and cellular longevity 2021;2021:4009308
FAM134B-Mediated ER-phagy Upregulation Attenuates AGEs-Induced Apoptosis and Senescence in Human Nucleus Pulposus Cells.
Luo R, Li S, Li G, Lu S, Zhang W, Liu H, Lei J, Ma L, Ke W, Liao Z, Wang B, Song Y, Wang K, Zhang Y, Yang C
Oxidative medicine and cellular longevity 2021;2021:3843145
Oxidative medicine and cellular longevity 2021;2021:3843145
Chlorogenic Acid Alleviates Colon Mucosal Damage Induced by a High-Fat Diet via Gut Microflora Adjustment to Increase Short-Chain Fatty Acid Accumulation in Rats.
Xie MG, Fei YQ, Wang Y, Wang WY, Wang Z
Oxidative medicine and cellular longevity 2021;2021:3456542
Oxidative medicine and cellular longevity 2021;2021:3456542
Electroacupuncture Ameliorates Depression-Like Behaviour in Rats by Enhancing Synaptic Plasticity via the GluN2B/CaMKII/CREB Signalling Pathway.
Zhang K, Liu R, Zhang J, Wei X, Gao Y, Ma W, Li Y, Cai W, Shen W
Evidence-based complementary and alternative medicine : eCAM 2021;2021:2146001
Evidence-based complementary and alternative medicine : eCAM 2021;2021:2146001
Inhibition of the PERK/TXNIP/NLRP3 Axis by Baicalin Reduces NLRP3 Inflammasome-Mediated Pyroptosis in Macrophages Infected with Mycobacterium tuberculosis.
Fu Y, Shen J, Li Y, Liu F, Ning B, Zheng Y, Jiang X
Mediators of inflammation 2021;2021:1805147
Mediators of inflammation 2021;2021:1805147
Microglia-Derived Exosomes Improve Spinal Cord Functional Recovery after Injury via Inhibiting Oxidative Stress and Promoting the Survival and Function of Endothelia Cells.
Peng W, Wan L, Luo Z, Xie Y, Liu Y, Huang T, Lu H, Hu J
Oxidative medicine and cellular longevity 2021;2021:1695087
Oxidative medicine and cellular longevity 2021;2021:1695087
Inhibiting PP2Acα Promotes the Malignant Phenotype of Gastric Cancer Cells through the ATM/METTL3 Axis.
Cheng Z, Gao S, Liang X, Lian C, Chen J, Fang C
BioMed research international 2021;2021:1015293
BioMed research international 2021;2021:1015293
Qingda granule exerts neuroprotective effects against ischemia/reperfusion-induced cerebral injury via lncRNA GAS5/miR-137 signaling pathway.
Zhang L, Cai Q, Lin S, Chen B, Jia B, Ye R, Weygant N, Chu J, Peng J
International journal of medical sciences 2021;18(7):1687-1698
International journal of medical sciences 2021;18(7):1687-1698
NSE, positively regulated by LINC00657-miR-93-5p axis, promotes small cell lung cancer (SCLC) invasion and epithelial-mesenchymal transition (EMT) process.
Lu L, Zha Z, Zhang P, Li D, Liu G
International journal of medical sciences 2021;18(16):3768-3779
International journal of medical sciences 2021;18(16):3768-3779
Simultaneous silencing Aurora-A and UHRF1 inhibits colorectal cancer cell growth through regulating expression of DNMT1 and STAT1.
Han J, Chen X, Xu J, Chu L, Li R, Sun N, Jiang Z, Liu H, Ge X, Zheng J, Yang J, Ikezoe T
International journal of medical sciences 2021;18(15):3437-3451
International journal of medical sciences 2021;18(15):3437-3451
GABAB receptor inhibits tumor progression and epithelial-mesenchymal transition via the regulation of Hippo/YAP1 pathway in colorectal cancer.
Wang H, Zhang H, Sun Z, Chen W, Miao C
International journal of biological sciences 2021;17(8):1953-1962
International journal of biological sciences 2021;17(8):1953-1962
Macrophage migration inhibitory factor regulates joint capsule fibrosis by promoting TGF-β1 production in fibroblasts.
Zhang Y, Liu Z, Wang K, Lu S, Fan S, Xu L, Cai B
International journal of biological sciences 2021;17(7):1837-1850
International journal of biological sciences 2021;17(7):1837-1850
Aurka deficiency in the intestinal epithelium promotes age-induced obesity via propionate-mediated AKT activation.
Sun N, Meng F, Zhao J, Li X, Li R, Han J, Chen X, Cheng W, Yang X, Kou Y, Zheng K, Yang J, Ikezoe T
International journal of biological sciences 2021;17(5):1302-1314
International journal of biological sciences 2021;17(5):1302-1314
Targeting HLA-F suppresses the proliferation of glioma cells via a reduction in hexokinase 2-dependent glycolysis.
Chen X, Sun N, Li R, Sang X, Li X, Zhao J, Han J, Yang J, Ikezoe T
International journal of biological sciences 2021;17(5):1263-1276
International journal of biological sciences 2021;17(5):1263-1276
FOXM1-induced miR-552 expression contributes to pancreatic cancer progression by targeting multiple tumor suppressor genes.
Wang X, Dou N, Wang J, Zhang Y, Li Y, Gao Y
International journal of biological sciences 2021;17(4):915-925
International journal of biological sciences 2021;17(4):915-925
AKR1B10 confers resistance to radiotherapy via FFA/TLR4/NF-κB axis in nasopharyngeal carcinoma.
Liu X, Hu Z, Qu J, Li J, Gong K, Wang L, Jiang J, Li X, He R, Duan L, Luo W, Xia C, Luo D
International journal of biological sciences 2021;17(3):756-767
International journal of biological sciences 2021;17(3):756-767
SOCS2 Suppresses Inflammation and Apoptosis during NASH Progression through Limiting NF-κB Activation in Macrophages.
Li S, Han S, Jin K, Yu T, Chen H, Zhou X, Tan Z, Zhang G
International journal of biological sciences 2021;17(15):4165-4175
International journal of biological sciences 2021;17(15):4165-4175
KMT5A downregulation participated in High Glucose-mediated EndMT via Upregulation of ENO1 Expression in Diabetic Nephropathy.
Lu L, Li X, Zhong Z, Zhou W, Zhou D, Zhu M, Miao C
International journal of biological sciences 2021;17(15):4093-4107
International journal of biological sciences 2021;17(15):4093-4107
The imbalance of PGD2-DPs pathway is involved in the type 2 diabetes brain injury by regulating autophagy.
Yang Y, Xiang P, Chen Q, Luo Y, Wang H, Li H, Yang L, Hu C, Zhang J, Li Y, Xia H, Chen Z, Yang J
International journal of biological sciences 2021;17(14):3993-4004
International journal of biological sciences 2021;17(14):3993-4004
Discovery of a novel HDACi structure that inhibits the proliferation of ovarian cancer cells in vivo and in vitro.
Bai M, Cui M, Li M, Yao X, Wu Y, Zheng L, Sun L, Song Q, Wang S, Liu L, Yu C, Huang Y
International journal of biological sciences 2021;17(13):3493-3507
International journal of biological sciences 2021;17(13):3493-3507
Deubiquitinase PSMD7 promotes the proliferation, invasion, and cisplatin resistance of gastric cancer cells by stabilizing RAD23B.
Wang J, Liu R, Mo H, Xiao X, Xu Q, Zhao W
International journal of biological sciences 2021;17(13):3331-3342
International journal of biological sciences 2021;17(13):3331-3342
NCTD Prevents Renal Interstitial Fibrosis via Targeting Sp1/lncRNA Gm26669 Axis.
Tian J, Xiao Z, Wei J, Shan Y, Zeng D, Tao Y, Fang X, Tang C, Chen X, Li Y
International journal of biological sciences 2021;17(12):3118-3132
International journal of biological sciences 2021;17(12):3118-3132
H2O2 gel bleaching induces cytotoxicity and pain conduction in dental pulp stem cells via intracellular reactive oxygen species on enamel/dentin disc.
Chen C, Huang X, Zhu W, Ding C, Huang P, Li R
PloS one 2021;16(9):e0257221
PloS one 2021;16(9):e0257221
Chirality and asymmetry increase the potency of candidate ADRM1/RPN13 inhibitors.
Anchoori RK, George L, Tseng SH, Lam B, Polkampally S, Amiano AD, Foran P, Tsingine H, Samanapally H, Carrizo Velasquez F, Das S, Xing D, Bin Salam A, Karanam B, Hung CF, Roden RBS
PloS one 2021;16(9):e0256937
PloS one 2021;16(9):e0256937
Harmine inhibits breast cancer cell migration and invasion by inducing the degradation of Twist1.
Nafie E, Lolarga J, Lam B, Guo J, Abdollahzadeh E, Rodriguez S, Glackin C, Liu J
PloS one 2021;16(2):e0247652
PloS one 2021;16(2):e0247652
HIV-1 Vpr protein upregulates microRNA-210-5p expression to induce G2 arrest by targeting TGIF2.
Qiao J, Peng Q, Qian F, You Q, Feng L, Hu S, Liu W, Huang L, Shu X, Sun B
PloS one 2021;16(12):e0261971
PloS one 2021;16(12):e0261971
Inhibition of histone deacetylation with vorinostat does not prevent tunicamycin-mediated acute kidney injury.
Carlisle RE, Farooqi S, Zhang MC, Liu S, Lu C, Phan A, Brimble E, Dickhout JG
PloS one 2021;16(11):e0260519
PloS one 2021;16(11):e0260519
Systematic identification of autophagy-related proteins in Aedes albopictus.
Wang Y, Qiao J, Zhang D, Zhong C, Wang S, Li X, Feng L, Shi S, Wang B, Liu Q
PloS one 2021;16(1):e0245694
PloS one 2021;16(1):e0245694
Accurately Controlled Delivery of Temozolomide by Biocompatible UiO-66-NH(2) Through Ultrasound to Enhance the Antitumor Efficacy and Attenuate the Toxicity for Treatment of Malignant Glioma.
Wan Z, Li C, Gu J, Qian J, Zhu J, Wang J, Li Y, Jiang J, Chen H, Luo C
International journal of nanomedicine 2021;16:6905-6922
International journal of nanomedicine 2021;16:6905-6922
Hypermethylation of the Nrf2 Promoter Induces Ferroptosis by Inhibiting the Nrf2-GPX4 Axis in COPD.
Zhang Z, Fu C, Liu J, Sai X, Qin C, Di T, Yang Y, Wu Y, Bian T
International journal of chronic obstructive pulmonary disease 2021;16:3347-3362
International journal of chronic obstructive pulmonary disease 2021;16:3347-3362
Total Flavonoids of Chuju Decrease Oxidative Stress and Cell Apoptosis in Ischemic Stroke Rats: Network and Experimental Analyses.
Wang C, Chen H, Jiang HH, Mao BB, Yu H
Frontiers in neuroscience 2021;15:772401
Frontiers in neuroscience 2021;15:772401
Photobiomodulation Promotes Repair Following Spinal Cord Injury by Regulating the Transformation of A1/A2 Reactive Astrocytes.
Wang X, Zhang Z, Zhu Z, Liang Z, Zuo X, Ju C, Song Z, Li X, Hu X, Wang Z
Frontiers in neuroscience 2021;15:768262
Frontiers in neuroscience 2021;15:768262
5-HT(7) Receptor Is Involved in Electroacupuncture Inhibition of Chronic Pain in the Spinal Cord.
Yuan XC, Yan XJ, Tian LX, Guo YX, Zhao YL, Baba SS, Wang YY, Liang LL, Jia H, Xu LP, Li L, Lin H, Huo FQ
Frontiers in neuroscience 2021;15:733779
Frontiers in neuroscience 2021;15:733779
IL-17 Inhibits Oligodendrocyte Progenitor Cell Proliferation and Differentiation by Increasing K(+) Channel Kv1.3.
Liu H, Yang X, Yang J, Yuan Y, Wang Y, Zhang R, Xiong H, Xu Y
Frontiers in cellular neuroscience 2021;15:679413
Frontiers in cellular neuroscience 2021;15:679413
Injection of Anti-proBDNF Attenuates Hippocampal-Dependent Learning and Memory Dysfunction in Mice With Sepsis-Associated Encephalopathy.
Cui YH, Zhou SF, Liu Y, Wang S, Li F, Dai RP, Hu ZL, Li CQ
Frontiers in neuroscience 2021;15:665757
Frontiers in neuroscience 2021;15:665757
Tetramethylpyrazine Alleviates Behavioral and Psychological Symptoms of Dementia Through Facilitating Hippocampal Synaptic Plasticity in Rats With Chronic Cerebral Hypoperfusion.
Tan Z, Qiu J, Zhang Y, Yang Q, Yin X, Li J, Liu G, Li H, Yang G
Frontiers in neuroscience 2021;15:646537
Frontiers in neuroscience 2021;15:646537
Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice.
Chang Y, Yao Y, Ma R, Wang Z, Hu J, Wu Y, Jiang X, Li L, Li G
Frontiers in neuroscience 2021;15:620176
Frontiers in neuroscience 2021;15:620176
IRE1α-XBP1 Affects the Mitochondrial Function of Aβ25-35-Treated SH-SY5Y Cells by Regulating Mitochondria-Associated Endoplasmic Reticulum Membranes.
Chu B, Li M, Cao X, Li R, Jin S, Yang H, Xu L, Wang P, Bi J
Frontiers in cellular neuroscience 2021;15:614556
Frontiers in cellular neuroscience 2021;15:614556
Oroxin B Attenuates Ovariectomy-Induced Bone Loss by Suppressing Osteoclast Formation and Activity.
Huang JM, Wang CZ, Lu SY, Wang Z, Yan ZQ
Drug design, development and therapy 2021;15:4811-4825
Drug design, development and therapy 2021;15:4811-4825
Doxazosin Attenuates Liver Fibrosis by Inhibiting Autophagy in Hepatic Stellate Cells via Activation of the PI3K/Akt/mTOR Signaling Pathway.
Xiu AY, Ding Q, Li Z, Zhang CQ
Drug design, development and therapy 2021;15:3643-3659
Drug design, development and therapy 2021;15:3643-3659
Baicalin Alleviates Oxidative Stress and Inflammation in Diabetic Nephropathy via Nrf2 and MAPK Signaling Pathway.
Ma L, Wu F, Shao Q, Chen G, Xu L, Lu F
Drug design, development and therapy 2021;15:3207-3221
Drug design, development and therapy 2021;15:3207-3221
Selective Inhibition of 11β-Hydroxysteroid Dehydrogenase Type 1 Attenuates High-Fat Diet-Induced Hepatic Steatosis in Mice.
Li H, Sheng J, Wang J, Gao H, Yu J, Ding G, Ding N, He W, Zha J
Drug design, development and therapy 2021;15:2309-2324
Drug design, development and therapy 2021;15:2309-2324
ADAM17 and NF-κB p65 form a positive feedback loop that facilitates human esophageal squamous cell carcinoma cell viability.
Gao L, Liu H, Xu R, Qiu J, Peng X, Yang Y, Zhang D, Qian J
International journal of clinical and experimental pathology 2021;14(7):845-854
International journal of clinical and experimental pathology 2021;14(7):845-854
Significance of TEAD Family in Diagnosis, Prognosis and Immune Response for Ovarian Serous Carcinoma.
Ren X, Wang X, Peng B, Liang Q, Cai Y, Gao K, Hu Y, Xu Z, Yan Y
International journal of general medicine 2021;14:7133-7143
International journal of general medicine 2021;14:7133-7143
Ginsenoside Rg1 Inhibits Microglia Pyroptosis Induced by Lipopolysaccharide Through Regulating STAT3 Signaling.
Yao Y, Li C, Qian F, Zhao Y, Shi X, Hong D, Ai Q, Zhong L
Journal of inflammation research 2021;14:6619-6632
Journal of inflammation research 2021;14:6619-6632
Gαi1 Promoted Proliferation, Migration and Invasion via Activating the Akt-mTOR/Erk-MAPK Signaling Pathway in Renal Cell Carcinoma.
Chen Z, Zhang Y, Wu X, Zhang J, Xu W, Shen C, Zheng B
OncoTargets and therapy 2021;14:2941-2952
OncoTargets and therapy 2021;14:2941-2952
Regulation of IFN-Is by MEF2D Promotes Inflammatory Homeostasis in Microglia.
Lu F, Wang R, Xia L, Nie T, Gao F, Yang S, Huang L, Shao K, Liu J, Yang Q
Journal of inflammation research 2021;14:2851-2863
Journal of inflammation research 2021;14:2851-2863
GADD45B Facilitates Metastasis of Ovarian Cancer Through Epithelial-Mesenchymal Transition.
Gong L, Cai L, Li G, Cai J, Yi X
OncoTargets and therapy 2021;14:255-269
OncoTargets and therapy 2021;14:255-269
Upregulation of Neuronal Cylindromatosis Expression is Essential for Electroacupuncture-Mediated Alleviation of Neuroinflammatory Injury by Regulating Microglial Polarization in Rats Subjected to Focal Cerebral Ischemia/Reperfusion.
Lin X, Zhan J, Jiang J, Ren Y
Journal of inflammation research 2021;14:2061-2078
Journal of inflammation research 2021;14:2061-2078
Orexin-A Attenuates Inflammatory Responses in Lipopolysaccharide-Induced Neural Stem Cells by Regulating NF-KB and Phosphorylation of MAPK/P38/Erk Pathways.
Ye W, Yan Y, Tang Y, Dong X, Chen G, Kang J, Huang L, Xiong Q, Feng Z
Journal of inflammation research 2021;14:2007-2017
Journal of inflammation research 2021;14:2007-2017
MiRNA-223-3p Affects Mantle Cell Lymphoma Development by Regulating the CHUK/NF-ƘB2 Signaling Pathway.
Yuan J, Zhang Q, Wu S, Yan S, Zhao R, Sun Y, Tian X, Zhou K
OncoTargets and therapy 2021;14:1553-1564
OncoTargets and therapy 2021;14:1553-1564
The Significance of HOXC11 and LSH in Survival Prediction in Gastric Adenocarcinoma.
Peng X, Sun J, Long Y, Xiao D, Zhou J, Tao Y, Liu S
OncoTargets and therapy 2021;14:1517-1529
OncoTargets and therapy 2021;14:1517-1529
Network pharmacology-guided mechanism study uncovers inhibitory effect of Mahuang Decoction on lung cancer growth by impeding Akt/ERK signaling pathways.
Pan Y, Chen Y, Wu C, Ai J, Wang Y, Jia J, Liu L
American journal of translational research 2021;13(4):2094-2110
American journal of translational research 2021;13(4):2094-2110
Myosin 1b promotes migration, invasion and glycolysis in cervical cancer via ERK/HIF-1α pathway.
Wen LJ, Hu XL, Li CY, Liu J, Li ZY, Li YZ, Zhou JY
American journal of translational research 2021;13(11):12536-12548
American journal of translational research 2021;13(11):12536-12548
Sevoflurane prevents pulmonary vascular remodeling and right ventricular dysfunction in pulmonary arterial hypertension in rats.
Zhai W, Li Y, Luo Y, Gao W, Liu S, Han J, Geng J
American journal of translational research 2021;13(10):11302-11315
American journal of translational research 2021;13(10):11302-11315
Dura cells in the etiopathogenesis of Crouzon syndrome: the effects of FGFR2 mutations in the dura cells on the proliferation of osteoblasts through the hippo/YAP mediated transcriptional regulation pathway.
Dong XH, Zhang MZ, Lai CZ, Li CC, Du L, Song GD, Zong XL, Jin XL
American journal of translational research 2021;13(10):11255-11270
American journal of translational research 2021;13(10):11255-11270
Schisandrin C attenuates renal damage in diabetic nephropathy by regulating macrophage polarization.
Wang Y, Cui J, Liu M, Shao Y, Dong X
American journal of translational research 2021;13(1):210-222
American journal of translational research 2021;13(1):210-222
Overexpression of the lncRNA AC012213.3 Promotes Proliferation, Migration and Invasion of Breast Cancer via RAD54B/PI3K/AKT Axis and is Associated with Worse Patient Prognosis.
Zhong H, Zeng G, He L
Cancer management and research 2021;13:7213-7223
Cancer management and research 2021;13:7213-7223
Calcitriol Alleviates MPP(+)- and MPTP-Induced Parthanatos Through the VDR/PARP1 Pathway in the Model of Parkinson's Disease.
Hu J, Wu J, Wan F, Kou L, Yin S, Sun Y, Li Y, Zhou Q, Wang T
Frontiers in aging neuroscience 2021;13:657095
Frontiers in aging neuroscience 2021;13:657095
ZNF750 exerted its Antitumor Action in Oral Squamous Cell Carcinoma by regulating E2F2.
Yang HL, Xu C, Yang YK, Tang WQ, Hong M, Pan L, Chen HY
Journal of Cancer 2021;12(24):7266-7276
Journal of Cancer 2021;12(24):7266-7276
LncRNA TMEM220-AS1 suppresses hepatocellular carcinoma cell proliferation and invasion by regulating the TMEM220/β-catenin axis.
Liu Y, Liu R, Zhao J, Zeng Z, Shi Z, Lu Q, Guo J, Li L, Yao Y, Liu X, Xu Q
Journal of Cancer 2021;12(22):6805-6813
Journal of Cancer 2021;12(22):6805-6813
LncRNA MALAT1 was regulated by HPV16 E7 independently of pRB in cervical cancer cells.
Wang T, Zhang W, Huang W, Hua Z, Li S
Journal of Cancer 2021;12(21):6344-6355
Journal of Cancer 2021;12(21):6344-6355
Inositol hexaphosphate sensitizes hepatocellular carcinoma to oxaliplatin relating inhibition of CCN2-LRP6-β-catenin-ABCG1 signaling pathway.
Liao X, Zhang Y, Xu B, Ali A, Liu X, Jia Q
Journal of Cancer 2021;12(20):6071-6080
Journal of Cancer 2021;12(20):6071-6080
Caspase-11-Mediated Hepatocytic Pyroptosis Promotes the Progression of Nonalcoholic Steatohepatitis.
Zhu Y, Zhao H, Lu J, Lin K, Ni J, Wu G, Tang H
Cellular and molecular gastroenterology and hepatology 2021;12(2):653-664
Cellular and molecular gastroenterology and hepatology 2021;12(2):653-664
SLC39A7 promotes malignant behaviors in glioma via the TNF-α-mediated NF-κB signaling pathway.
Chen L, Zhou J, Li L, Zhao J, Li H, Zheng W, Xu J, Jing Z
Journal of Cancer 2021;12(15):4530-4541
Journal of Cancer 2021;12(15):4530-4541
Demethylzelasteral inhibits proliferation and EMT via repressing Wnt/β-catenin signaling in esophageal squamous cell carcinoma.
Yu J, Wang W, Liu B, Gu J, Chen S, Cui Y, Sun G
Journal of Cancer 2021;12(13):3967-3975
Journal of Cancer 2021;12(13):3967-3975
CDK5 Knockdown inhibits proliferation and induces apoptosis and Cell Cycle Arrest in Human Glioblastoma.
Zhou Y, Wang X, Lv P, Yu H, Jiang X
Journal of Cancer 2021;12(13):3958-3966
Journal of Cancer 2021;12(13):3958-3966
Proteomic Analysis of the Alterations in Follicular Fluid Proteins During Oocyte Maturation in Humans.
Wang C, Fei X, Zhang H, Zhou W, Cheng Z, Feng Y
Frontiers in endocrinology 2021;12:830691
Frontiers in endocrinology 2021;12:830691
Diosgenin From Dioscorea Nipponica Rhizoma Against Graves' Disease-On Network Pharmacology and Experimental Evaluation.
Xin J, Cheng W, Yu Y, Chen J, Zhang X, Shao S
Frontiers in pharmacology 2021;12:806829
Frontiers in pharmacology 2021;12:806829
Exploring the Pharmacological Mechanisms of Xihuang Pills Against Prostate Cancer via Integrating Network Pharmacology and Experimental Validation In Vitro and In Vivo.
Wu Y, You X, Lin Q, Xiong W, Guo Y, Huang Z, Dai X, Chen Z, Mei S, Long Y, Tian X, Zhou Q
Frontiers in pharmacology 2021;12:791269
Frontiers in pharmacology 2021;12:791269
Proteomics Study Reveals the Anti-Depressive Mechanisms and the Compatibility Advantage of Chaihu-Shugan-San in a Rat Model of Chronic Unpredictable Mild Stress.
Zhu X, Li T, Hu E, Duan L, Zhang C, Wang Y, Tang T, Yang Z, Fan R
Frontiers in pharmacology 2021;12:791097
Frontiers in pharmacology 2021;12:791097
Punicalin Attenuates Breast Cancer-Associated Osteolysis by Inhibiting the NF-κB Signaling Pathway of Osteoclasts.
Li T, Jiang G, Hu X, Yang D, Tan T, Gao Z, Chen Z, Xiang C, Li S, Ouyang Z, Guo X
Frontiers in pharmacology 2021;12:789552
Frontiers in pharmacology 2021;12:789552
Baicalein Alleviates Osteoarthritis Progression in Mice by Protecting Subchondral Bone and Suppressing Chondrocyte Apoptosis Based on Network Pharmacology.
Yi N, Mi Y, Xu X, Li N, Zeng F, Yan K, Tan K, Kuang G, Lu M
Frontiers in pharmacology 2021;12:788392
Frontiers in pharmacology 2021;12:788392
Chitosan Protects Immunosuppressed Mice Against Cryptosporidium parvum Infection Through TLR4/STAT1 Signaling Pathways and Gut Microbiota Modulation.
Rahman SU, Gong H, Mi R, Huang Y, Han X, Chen Z
Frontiers in immunology 2021;12:784683
Frontiers in immunology 2021;12:784683
Integrated Network Pharmacology and Lipidomics to Reveal the Inhibitory Effect of Qingfei Oral Liquid on Excessive Autophagy in RSV-Induced Lung Inflammation.
Lin L, An L, Chen H, Feng L, Lu M, Liu Y, Chu C, Shan J, Xie T, Wang X, Wang S
Frontiers in pharmacology 2021;12:777689
Frontiers in pharmacology 2021;12:777689
Inhibiting YAP in Endothelial Cells From Entering the Nucleus Attenuates Blood-Brain Barrier Damage During Ischemia-Reperfusion Injury.
Gong S, Ma H, Zheng F, Huang J, Zhang Y, Yu B, Li F, Kou J
Frontiers in pharmacology 2021;12:777680
Frontiers in pharmacology 2021;12:777680
Acid-Sensing Ion Channel 1/Calpain1 Activation Impedes Macrophage ATP-Binding Cassette Protein A1-Mediated Cholesterol Efflux Induced by Extracellular Acidification.
Wang YM, Tan MY, Zhang RJ, Qiu MY, Fu YS, Xie XJ, Gu HF
Frontiers in physiology 2021;12:777386
Frontiers in physiology 2021;12:777386
Activation of TAF9 via Danshensu-Induced Upregulation of HDAC1 Expression Alleviates Non-alcoholic Fatty Liver Disease.
Wang R, Wang Z, Sun R, Fu R, Sun Y, Zhu M, Geng Y, Gao D, Tian X, Zhao Y, Yao J
Frontiers in pharmacology 2021;12:775528
Frontiers in pharmacology 2021;12:775528
Enhancing Fatty Acids Oxidation via L-Carnitine Attenuates Obesity-Related Atrial Fibrillation and Structural Remodeling by Activating AMPK Signaling and Alleviating Cardiac Lipotoxicity.
Zhang Y, Fu Y, Jiang T, Liu B, Sun H, Zhang Y, Fan B, Li X, Qin X, Zheng Q
Frontiers in pharmacology 2021;12:771940
Frontiers in pharmacology 2021;12:771940
CircEpc1 Promotes Ricin Toxin-Induced Inflammation via Activation of NF-κB and MAPK Signaling Pathways by Sponging miR-5114.
Dong M, Zhang X, Yu H, Wang Y, Chang Y, Sun C, Zhang J, Zhao N, Yu K, Sun G, Zhao G, Xu N, Liu W
Frontiers in pharmacology 2021;12:767900
Frontiers in pharmacology 2021;12:767900
Screening and Functional Analysis of TEK Mutations in Chinese Children With Primary Congenital Glaucoma.
Qiao Y, Chen Y, Tan C, Sun X, Chen X, Chen J
Frontiers in genetics 2021;12:764509
Frontiers in genetics 2021;12:764509
circKLF4 Upregulates Klf4 and Endoglin to Promote Odontoblastic Differentiation of Mouse Dental Papilla Cells via Sponging miRNA-1895 and miRNA-5046.
Zhang Y, Zhang H, Yuan G, Yang G
Frontiers in physiology 2021;12:760223
Frontiers in physiology 2021;12:760223
Trametinib Inhibits the Growth and Aerobic Glycolysis of Glioma Cells by Targeting the PKM2/c-Myc Axis.
Gao M, Yang J, Gong H, Lin Y, Liu J
Frontiers in pharmacology 2021;12:760055
Frontiers in pharmacology 2021;12:760055
Dauricine Attenuates Vascular Endothelial Inflammation Through Inhibiting NF-κB Pathway.
Hu J, Chen R, An J, Wang Y, Liang M, Huang K
Frontiers in pharmacology 2021;12:758962
Frontiers in pharmacology 2021;12:758962
The ALDH Family Contributes to Immunocyte Infiltration, Proliferation and Epithelial-Mesenchymal Transformation in Glioma.
Wang Z, Mo Y, Tan Y, Wen Z, Dai Z, Zhang H, Zhang X, Feng S, Liang X, Song T, Cheng Q
Frontiers in immunology 2021;12:756606
Frontiers in immunology 2021;12:756606
β2-Adrenergic Receptor Enhances the Alternatively Activated Macrophages and Promotes Biliary Injuries Caused by Helminth Infection.
Koda S, Zhang B, Zhou QY, Xu N, Li J, Liu JX, Liu M, Lv ZY, Wang JL, Shi Y, Gao S, Yu Q, Li XY, Xu YH, Chen JX, Tekengne BOT, Adzika GK, Tang RX, Sun H, Zheng KY, Yan C
Frontiers in immunology 2021;12:754208
Frontiers in immunology 2021;12:754208
Characterization of Pathogenesis and Inflammatory Responses to Experimental Parechovirus Encephalitis.
Jan MW, Su HL, Chang TH, Tsai KJ
Frontiers in immunology 2021;12:753683
Frontiers in immunology 2021;12:753683
The Effect of Ellagic Acid on Hepatic Lipid Metabolism and Antioxidant Activity in Mice.
Xu Q, Li S, Tang W, Yan J, Wei X, Zhou M, Diao H
Frontiers in physiology 2021;12:751501
Frontiers in physiology 2021;12:751501
SARS-CoV-2 Nsp5 Activates NF-κB Pathway by Upregulating SUMOylation of MAVS.
Li W, Qiao J, You Q, Zong S, Peng Q, Liu Y, Hu S, Liu W, Li S, Shu X, Sun B
Frontiers in immunology 2021;12:750969
Frontiers in immunology 2021;12:750969
Rhein Relieves Oxidative Stress in an Aβ(1-42) Oligomer-Burdened Neuron Model by Activating the SIRT1/PGC-1α-Regulated Mitochondrial Biogenesis.
Yin Z, Geng X, Zhang Z, Wang Y, Gao X
Frontiers in pharmacology 2021;12:746711
Frontiers in pharmacology 2021;12:746711
Anlotinib Inhibits PFKFB3-Driven Glycolysis in Myofibroblasts to Reverse Pulmonary Fibrosis.
Chen W, Zhang J, Zhong W, Liu Y, Lu Y, Zeng Z, Huang H, Wan X, Meng X, Zou F, Cai S, Dong H
Frontiers in pharmacology 2021;12:744826
Frontiers in pharmacology 2021;12:744826
Mechanisms Underlying Gastrodin Alleviating Vincristine-Induced Peripheral Neuropathic Pain.
Wang X, Zhang B, Li X, Liu X, Wang S, Xie Y, Pi J, Yang Z, Li J, Jia Q, Zhang Y
Frontiers in pharmacology 2021;12:744663
Frontiers in pharmacology 2021;12:744663
Identification of a Novel Gene Correlated With Vascular Smooth Muscle Cells Proliferation and Migration in Chronic Thromboembolic Pulmonary Hypertension.
Wang F, Sun C, Lv X, Sun M, Si C, Zhen Y, Guo J, Sun W, Ye Z, Wen J, Liu P
Frontiers in physiology 2021;12:744219
Frontiers in physiology 2021;12:744219
Morchella importuna Flavones Improve Intestinal Integrity in Dextran Sulfate Sodium-Challenged Mice.
Xu Y, Xie L, Tang J, He X, Zhang Z, Chen Y, Zhou J, Gan B, Peng W
Frontiers in microbiology 2021;12:742033
Frontiers in microbiology 2021;12:742033
Probiotic Interventions Alleviate Food Allergy Symptoms Correlated With Cesarean Section: A Murine Model.
Jin BY, Li Z, Xia YN, Li LX, Zhao ZX, Li XY, Li Y, Li B, Zhou RC, Fu SC, Li SY, Li YQ
Frontiers in immunology 2021;12:741371
Frontiers in immunology 2021;12:741371
High-Salt Attenuates the Efficacy of Dapagliflozin in Tubular Protection by Impairing Fatty Acid Metabolism in Diabetic Kidney Disease.
Zou M, Chen Y, Zheng Z, Sheng S, Jia Y, Wang X, Ren S, Yang Y, Li X, Dong W, Guan M, Zhang Q, Xue Y
Frontiers in pharmacology 2021;12:741087
Frontiers in pharmacology 2021;12:741087
Tetrandrine Modulates Rheb-mTOR Signaling-Mediated Selective Autophagy and Protects Pulmonary Fibrosis.
Liu Y, Zhong W, Zhang J, Chen W, Lu Y, Qiao Y, Zeng Z, Huang H, Cai S, Dong H
Frontiers in pharmacology 2021;12:739220
Frontiers in pharmacology 2021;12:739220
MIR337-3p Enhances Mycobacterial Pathogenicity Involving TLR4/MYD88 and STAT3 Signals, Impairing VDR Antimicrobial Response and Fast-Acting Immunity.
Liang S, Huang G, Wu T, Peng Y, Liu X, Ji X, Sha W, Wang F, Shen L, Shen H
Frontiers in immunology 2021;12:739219
Frontiers in immunology 2021;12:739219
Paeoniflorin Suppresses TBHP-Induced Oxidative Stress and Apoptosis in Human Umbilical Vein Endothelial Cells via the Nrf2/HO-1 Signaling Pathway and Improves Skin Flap Survival.
Jiang J, Dong C, Zhai L, Lou J, Jin J, Cheng S, Chen Z, Guo X, Lin D, Ding J, Gao W
Frontiers in pharmacology 2021;12:735530
Frontiers in pharmacology 2021;12:735530
β-Adrenergic Receptor Inhibitor and Oncolytic Herpesvirus Combination Therapy Shows Enhanced Antitumoral and Antiangiogenic Effects on Colorectal Cancer.
Hu J, Chen C, Lu R, Zhang Y, Wang Y, Hu Q, Li W, Wang S, Jing O, Yi H, Zhang W, Chen L, Huang W, Luo J, McLeod HL, Xu R, He Y
Frontiers in pharmacology 2021;12:735278
Frontiers in pharmacology 2021;12:735278
Polysaccharides Extracted From Panax Ginseng C.A. Mey Enhance Complement Component 4 Biosynthesis in Human Hepatocytes.
Liu S, Liu F, Wang T, Liu J, Hu C, Sun L, Wang G
Frontiers in pharmacology 2021;12:734394
Frontiers in pharmacology 2021;12:734394
Berberine Reduces Lipid Accumulation by Promoting Fatty Acid Oxidation in Renal Tubular Epithelial Cells of the Diabetic Kidney.
Rong Q, Han B, Li Y, Yin H, Li J, Hou Y
Frontiers in pharmacology 2021;12:729384
Frontiers in pharmacology 2021;12:729384
Clozapine Induced Disturbances in Hepatic Glucose Metabolism: The Potential Role of PGRMC1 Signaling.
Cao T, Chen Q, Zhang B, Wu X, Zeng C, Zhang S, Cai H
Frontiers in endocrinology 2021;12:727371
Frontiers in endocrinology 2021;12:727371
Association of Pericyte Loss With Microthrombosis After Subarachnoid Hemorrhage in ApoE-Deficient Mice.
Pang J, Wu Y, Peng J, Yang P, Chen L, Jiang Y
Frontiers in neurology 2021;12:726520
Frontiers in neurology 2021;12:726520
Protective Effect of Oxytocin on Ventilator-Induced Lung Injury Through NLRP3-Mediated Pathways.
Yang X, An X, Wang C, Gao F, Lin Y, Chen W, Deng Q, Xu D, Li S, Zhang P, Sun B, Hou Y, Wu J
Frontiers in pharmacology 2021;12:722907
Frontiers in pharmacology 2021;12:722907
Ddb1 Is Essential for the Expansion of CD4(+) Helper T Cells by Regulating Cell Cycle Progression and Cell Death.
Yang L, Chen W, Li L, Xiao Y, Fan S, Zhang Q, Xia T, Li M, Hong Y, Zhao T, Li Q, Liu WH, Xiao N
Frontiers in immunology 2021;12:722273
Frontiers in immunology 2021;12:722273
Identification of Potential Prognostic Biomarker for Predicting Survival in Multiple Myeloma Using Bioinformatics Analysis and Experiments.
Zhou J, Zhang M, Zhang Y, Shi X, Liu L, Yao R
Frontiers in genetics 2021;12:722132
Frontiers in genetics 2021;12:722132
The Downregulation of eIF3a Contributes to Vemurafenib Resistance in Melanoma by Activating ERK via PPP2R1B.
Jiang SL, Wang ZB, Zhu T, Jiang T, Fei JF, Liu C, Luo C, Cheng Y, Liu ZQ
Frontiers in pharmacology 2021;12:720619
Frontiers in pharmacology 2021;12:720619
Inhibition of the Inflammasome Activity of NLRP3 Attenuates HDM-Induced Allergic Asthma.
Ma M, Li G, Qi M, Jiang W, Zhou R
Frontiers in immunology 2021;12:718779
Frontiers in immunology 2021;12:718779
Exploring the Critical Components and Therapeutic Mechanisms of Perilla frutescens L. in the Treatment of Chronic Kidney Disease via Network Pharmacology.
Yong C, Zhang Z, Huang G, Yang Y, Zhu Y, Qian L, Tian F, Liu L, Wu Q, Xu Z, Chen C, Zhao J, Gao K, Zhou E
Frontiers in pharmacology 2021;12:717744
Frontiers in pharmacology 2021;12:717744
Weighted Gene Co-Expression Network Analysis Identifies ANGPTL4 as a Key Regulator in Diabetic Cardiomyopathy via FAK/SIRT3/ROS Pathway in Cardiomyocyte.
Dai L, Xie Y, Zhang W, Zhong X, Wang M, Jiang H, He Z, Liu X, Zeng H, Wang H
Frontiers in endocrinology 2021;12:705154
Frontiers in endocrinology 2021;12:705154
Novel Pyrazolo[3,4-b] Pyridine Derivative (HLQ2g) Attenuates Hypoxic Pulmonary Hypertension via Restoring cGKI Expression and BMP Signaling Pathway.
Li L, Yin M, Hu L, Tian X, He X, Zhao C, Li Y, Li Q, Li X
Frontiers in pharmacology 2021;12:691405
Frontiers in pharmacology 2021;12:691405
miR-25 Regulates Gastric Cancer Cell Growth and Apoptosis by Targeting EGR2.
Yang L, Li L, Chang P, Wei M, Chen J, Zhu C, Jia J
Frontiers in genetics 2021;12:690196
Frontiers in genetics 2021;12:690196
An Escherichia coli Effector Protein EspF May Induce Host DNA Damage via Interaction With SMC1.
Fu M, Liang S, Wu J, Hua Y, Chen H, Zhang Z, Liu J, Li X, Zhang B, Zhao W, Wan C
Frontiers in microbiology 2021;12:682064
Frontiers in microbiology 2021;12:682064
Lidocaine Promoted Ferroptosis by Targeting miR-382-5p /SLC7A11 Axis in Ovarian and Breast Cancer.
Sun D, Li YC, Zhang XY
Frontiers in pharmacology 2021;12:681223
Frontiers in pharmacology 2021;12:681223
Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke.
Xu ZQ, Zhang JJ, Kong N, Zhang GY, Ke P, Han T, Su DF, Liu C
Frontiers in pharmacology 2021;12:676589
Frontiers in pharmacology 2021;12:676589
c-Myc Upregulated by High Glucose Inhibits HaCaT Differentiation by S100A6 Transcriptional Activation.
Zhang J, Yang P, Liu D, Gao M, Wang J, Wang X, Liu Y, Zhang X
Frontiers in endocrinology 2021;12:676403
Frontiers in endocrinology 2021;12:676403
High Mobility Group Box 1 (HMGB1) Induces Toll-Like Receptor 4-Mediated Production of the Immunosuppressive Protein Galectin-9 in Human Cancer Cells.
Teo Hansen Selnø A, Schlichtner S, Yasinska IM, Sakhnevych SS, Fiedler W, Wellbrock J, Berger SM, Klenova E, Gibbs BF, Fasler-Kan E, Sumbayev VV
Frontiers in immunology 2021;12:675731
Frontiers in immunology 2021;12:675731
Effects of Sodium Ferulate on Cardiac Hypertrophy Are via the CaSR-Mediated Signaling Pathway.
Chen P, Wen Z, Shi W, Li Z, Chen X, Gao Y, Xu S, Gong Q, Deng J
Frontiers in pharmacology 2021;12:674570
Frontiers in pharmacology 2021;12:674570
SARS-CoV-2 Membrane Protein Inhibits Type I Interferon Production Through Ubiquitin-Mediated Degradation of TBK1.
Sui L, Zhao Y, Wang W, Wu P, Wang Z, Yu Y, Hou Z, Tan G, Liu Q
Frontiers in immunology 2021;12:662989
Frontiers in immunology 2021;12:662989
Astragaloside IV Inhibits Galactose-Deficient IgA1 Secretion via miR-98-5p in Pediatric IgA Nephropathy.
Liu C, Li X, Shuai L, Dang X, Peng F, Zhao M, Xiong S, Liu Y, He Q
Frontiers in pharmacology 2021;12:658236
Frontiers in pharmacology 2021;12:658236
Circ_0040039 May Aggravate Intervertebral Disk Degeneration by Regulating the MiR-874-3p-ESR1 Pathway.
Li Y, Wang X, Xu H, Li G, Huo Z, Du L, Zhang K, Shen L, Li H, Xu B
Frontiers in genetics 2021;12:656759
Frontiers in genetics 2021;12:656759
A New Chalcone Derivative C49 Reverses Doxorubicin Resistance in MCF-7/DOX Cells by Inhibiting P-Glycoprotein Expression.
Wang T, Dong J, Yuan X, Wen H, Wu L, Liu J, Sui H, Deng W
Frontiers in pharmacology 2021;12:653306
Frontiers in pharmacology 2021;12:653306
Nicotine Causes Mitochondrial Dynamics Imbalance and Apoptosis Through ROS Mediated Mitophagy Impairment in Cardiomyocytes.
Meng TT, Wang W, Meng FL, Wang SY, Wu HH, Chen JM, Zheng Y, Wang GX, Zhang MX, Li Y, Su GH
Frontiers in physiology 2021;12:650055
Frontiers in physiology 2021;12:650055
Quercetin Attenuates Trauma-Induced Heterotopic Ossification by Tuning Immune Cell Infiltration and Related Inflammatory Insult.
Li J, Sun Z, Luo G, Wang S, Cui H, Yao Z, Xiong H, He Y, Qian Y, Fan C
Frontiers in immunology 2021;12:649285
Frontiers in immunology 2021;12:649285
TOX Acts as a Tumor Suppressor by Inhibiting mTOR Signaling in Colorectal Cancer.
Yang M, Huang Q, Li C, Jiang Z, Sun J, Wang Z, Liang R, Li D, Li B, Zhao H
Frontiers in immunology 2021;12:647540
Frontiers in immunology 2021;12:647540
Identification of a RAD52 Inhibitor Inducing Synthetic Lethality in BRCA2-Deficient Cancer Cells.
Yang Q, Li Y, Sun R, Li J
Frontiers in pharmacology 2021;12:637825
Frontiers in pharmacology 2021;12:637825
BYHWD Alleviates Inflammatory Response by NIK-Mediated Repression of the Noncanonical NF-κB Pathway During ICH Recovery.
Xiao W, He Z, Luo W, Feng D, Wang Y, Tang T, Yang A, Luo J
Frontiers in pharmacology 2021;12:632407
Frontiers in pharmacology 2021;12:632407
Increased Angiogenin Expression Correlates With Radiation Resistance and Predicts Poor Survival for Patients With Nasopharyngeal Carcinoma.
Guo SS, Liang YJ, Liu LT, Chen QY, Wen YF, Liu SL, Sun XS, Tang QN, Li XY, Mai HQ, Tang LQ
Frontiers in pharmacology 2021;12:627935
Frontiers in pharmacology 2021;12:627935
Meteorin-Like Ameliorates β Cell Function by Inhibiting β Cell Apoptosis of and Promoting β Cell Proliferation via Activating the WNT/β-Catenin Pathway.
Hu W, Wang R, Sun B
Frontiers in pharmacology 2021;12:627147
Frontiers in pharmacology 2021;12:627147
Duck Hepatitis A Virus Type 1 Induces eIF2α Phosphorylation-Dependent Cellular Translation Shutoff via PERK/GCN2.
Liu Y, Cheng A, Wang M, Mao S, Ou X, Yang Q, Wu Y, Gao Q, Liu M, Zhang S, Huang J, Jia R, Zhu D, Chen S, Zhao X, Yu Y, Liu Y, Zhang L, Tian B, Pan L
Frontiers in microbiology 2021;12:624540
Frontiers in microbiology 2021;12:624540
In Vivo Inhibition of MicroRNA-326 in a NOD.H-2(h4) Mouse Model of Autoimmune Thyroiditis.
Zhao N, Wang Z, Cui X, Wang S, Fan C, Li Y, Shan Z, Teng W
Frontiers in immunology 2021;12:620916
Frontiers in immunology 2021;12:620916
IR-61 Improves Voiding Function via Mitochondrial Protection in Diabetic Rats.
Wang J, Dai L, Yue X, Shen C, Li T, Long L, Zhi Y, Wang Y, Shen G, Shi C, Liu Y, Fang Q, Li W
Frontiers in pharmacology 2021;12:608637
Frontiers in pharmacology 2021;12:608637
Bortezomib Sustains T Cell Function by Inducing miR-155-Mediated Downregulation of SOCS1 and SHIP1.
Renrick AN, Thounaojam MC, de Aquino MTP, Chaudhuri E, Pandhare J, Dash C, Shanker A
Frontiers in immunology 2021;12:607044
Frontiers in immunology 2021;12:607044
Inhibition of Shear-Induced Platelet Aggregation by Xueshuantong via Targeting Piezo1 Channel-Mediated Ca(2+) Signaling Pathway.
Liu L, Zhang Q, Xiao S, Sun Z, Ding S, Chen Y, Wang L, Yin X, Liao F, Jiang LH, Xue M, You Y
Frontiers in pharmacology 2021;12:606245
Frontiers in pharmacology 2021;12:606245
SFTSV Infection Induced Interleukin-1β Secretion Through NLRP3 Inflammasome Activation.
Liu JW, Chu M, Jiao YJ, Zhou CM, Qi R, Yu XJ
Frontiers in immunology 2021;12:595140
Frontiers in immunology 2021;12:595140
PHB2 promotes tumorigenesis via RACK1 in non-small cell lung cancer.
Wu B, Chang N, Xi H, Xiong J, Zhou Y, Wu Y, Wu S, Wang N, Yi H, Song Y, Chen L, Zhang J
Theranostics 2021;11(7):3150-3166
Theranostics 2021;11(7):3150-3166
Necroptosis pathway blockage attenuates PFKFB3 inhibitor-induced cell viability loss and genome instability in colorectal cancer cells.
Yan S, Li Q, Zhang D, Wang X, Xu Y, Zhang C, Guo D, Bao Y
American journal of cancer research 2021;11(5):2062-2080
American journal of cancer research 2021;11(5):2062-2080
Targeting of glioma stem-like cells with a parthenolide derivative ACT001 through inhibition of AEBP1/PI3K/AKT signaling.
Hou Y, Sun B, Liu W, Yu B, Shi Q, Luo F, Bai Y, Feng H
Theranostics 2021;11(2):555-566
Theranostics 2021;11(2):555-566
Local administration of liposomal-based Srpx2 gene therapy reverses pulmonary fibrosis by blockading fibroblast-to-myofibroblast transition.
Wang Q, Liu J, Hu Y, Pan T, Xu Y, Yu J, Xiong W, Zhou Q, Wang Y
Theranostics 2021;11(14):7110-7125
Theranostics 2021;11(14):7110-7125
KAT6A, a novel regulator of β-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1.
Liu W, Zhan Z, Zhang M, Sun B, Shi Q, Luo F, Zhang M, Zhang W, Hou Y, Xiao X, Li Y, Feng H
Theranostics 2021;11(13):6278-6292
Theranostics 2021;11(13):6278-6292
Aurka loss in CD19(+) B cells promotes megakaryocytopoiesis via IL-6/STAT3 signaling-mediated thrombopoietin production.
Chen X, Wang C, Sun N, Pan S, Li R, Li X, Zhao J, Tong H, Tang Y, Han J, Qiao J, Qiu H, Wang H, Yang J, Ikezoe T
Theranostics 2021;11(10):4655-4671
Theranostics 2021;11(10):4655-4671
Ese-3 contributes to colon cancer progression by downregulating EHD2 and transactivating INPP4B.
Li J, Yang J, Hua L, Wang R, Li H, Zhang C, Zhang H, Li S, Zhu L, Su H
American journal of cancer research 2021;11(1):92-107
American journal of cancer research 2021;11(1):92-107
Cardiac telocytes inhibit cardiac microvascular endothelial cell apoptosis through exosomal miRNA-21-5p-targeted cdip1 silencing to improve angiogenesis following myocardial infarction.
Liao Z, Chen Y, Duan C, Zhu K, Huang R, Zhao H, Hintze M, Pu Q, Yuan Z, Lv L, Chen H, Lai B, Feng S, Qi X, Cai D
Theranostics 2021;11(1):268-291
Theranostics 2021;11(1):268-291
Deferoxamine Counteracts Cisplatin Resistance in A549 Lung Adenocarcinoma Cells by Increasing Vulnerability to Glutamine Deprivation-Induced Cell Death.
Liu WJ, Pan PY, Sun Y, Wang JB, Zhou H, Xie X, Duan ZY, Dong HY, Chen WN, Zhang LD, Wang C
Frontiers in oncology 2021;11:794735
Frontiers in oncology 2021;11:794735
Phospholipid Phosphatase 4 as a Driver of Malignant Glioma and Pancreatic Adenocarcinoma.
Tian W, Wang P, Wang Z, Qi H, Dong J, Wang H
Frontiers in oncology 2021;11:790676
Frontiers in oncology 2021;11:790676
Modulated TRPC1 Expression Predicts Sensitivity of Breast Cancer to Doxorubicin and Magnetic Field Therapy: Segue Towards a Precision Medicine Approach.
Tai YK, Chan KKW, Fong CHH, Ramanan S, Yap JLY, Yin JN, Yip YS, Tan WR, Koh APF, Tan NS, Chan CW, Huang RYJ, Li JZ, Fröhlich J, Franco-Obregón A
Frontiers in oncology 2021;11:783803
Frontiers in oncology 2021;11:783803
ITGA5 Predicts Dual-Drug Resistance to Temozolomide and Bevacizumab in Glioma.
Shi Y, Wu M, Liu Y, Hu L, Wu H, Xie L, Liu Z, Wu A, Chen L, Xu C
Frontiers in oncology 2021;11:769592
Frontiers in oncology 2021;11:769592
Prognostic Value and Correlation With Tumor Immune Infiltration of a Novel Metabolism-Related Gene Signature in Pancreatic Cancer.
Chen H, Zu F, Zeng T, Chen Z, Wei J, Liu P, Li Z, Zhou L, Wang H, Tan H, Tan X
Frontiers in oncology 2021;11:757791
Frontiers in oncology 2021;11:757791
Autophagy-Induced HDAC6 Activity During Hypoxia Regulates Mitochondrial Energy Metabolism Through the β-Catenin/COUP-TFII Axis in Hepatocellular Carcinoma Cells.
Yan X, Qu X, Liu B, Zhao Y, Xu L, Yu S, Wang J, Wang L, Su J
Frontiers in oncology 2021;11:742460
Frontiers in oncology 2021;11:742460
Purified Vitexin Compound 1 Serves as a Promising Antineoplastic Agent in Ovarian Cancer.
Ma K, Wang K, Zhou Y, Liu N, Guo W, Qi J, Hu Z, Su S, Tang P, Zhou X
Frontiers in oncology 2021;11:734708
Frontiers in oncology 2021;11:734708
Identification of Glycolysis-Related lncRNAs and the Novel lncRNA WAC-AS1 Promotes Glycolysis and Tumor Progression in Hepatocellular Carcinoma.
Xia X, Zhang H, Xia P, Zhu Y, Liu J, Xu K, Yuan Y
Frontiers in oncology 2021;11:733595
Frontiers in oncology 2021;11:733595
Honokiol Suppresses Perineural Invasion of Pancreatic Cancer by Inhibiting SMAD2/3 Signaling.
Qin T, Li J, Xiao Y, Wang X, Gong M, Wang Q, Zhu Z, Zhang S, Zhang W, Cao F, Han L, Wang Z, Ma Q, Sha H
Frontiers in oncology 2021;11:728583
Frontiers in oncology 2021;11:728583
The Anti-Colon Cancer Effects of Essential Oil of Curcuma phaeocaulis Through Tumour Vessel Normalisation.
Feng Y, Deng L, Guo H, Zhao Y, Peng F, Wang G, Yu C
Frontiers in oncology 2021;11:728464
Frontiers in oncology 2021;11:728464
Downregulation of miR-142a Contributes to the Enhanced Anti-Apoptotic Ability of Murine Chronic Myelogenous Leukemia Cells.
Chen Z, Xie Y, Liu D, Liu P, Li F, Zhang Z, Zhang M, Wang X, Zhang Y, Sun X, Huang Q
Frontiers in oncology 2021;11:718731
Frontiers in oncology 2021;11:718731
Cystatin-B Negatively Regulates the Malignant Characteristics of Oral Squamous Cell Carcinoma Possibly Via the Epithelium Proliferation/Differentiation Program.
Xu TT, Zeng XW, Wang XH, Yang LX, Luo G, Yu T
Frontiers in oncology 2021;11:707066
Frontiers in oncology 2021;11:707066
NEK7 Promotes Pancreatic Cancer Progression And Its Expression Is Correlated With Poor Prognosis.
Yan Z, Qu J, Li Z, Yi J, Su Y, Lin Q, Yu G, Lin Z, Yin W, Lu F, Liu J
Frontiers in oncology 2021;11:705797
Frontiers in oncology 2021;11:705797
Transcriptomic Analyses of the Adenoma-Carcinoma Sequence Identify Hallmarks Associated With the Onset of Colorectal Cancer.
Hong Q, Li B, Cai X, Lv Z, Cai S, Zhong Y, Wen B
Frontiers in oncology 2021;11:704531
Frontiers in oncology 2021;11:704531
The EIF4A3/CASC2/RORA Feedback Loop Regulates the Aggressive Phenotype in Glioblastomas.
Zhao J, Jiang Y, Chen L, Ma Y, Zhang H, Zhou J, Li H, Jing Z
Frontiers in oncology 2021;11:699933
Frontiers in oncology 2021;11:699933
Aeromonas sobria Induces Proinflammatory Cytokines Production in Mouse Macrophages via Activating NLRP3 Inflammasome Signaling Pathways.
Zhang W, Li Z, Yang H, Wang G, Liu G, Wang Y, Bello BK, Zhao P, Liang W, Dong J
Frontiers in cellular and infection microbiology 2021;11:691445
Frontiers in cellular and infection microbiology 2021;11:691445
Transcriptomic Analyses Reveal B-Cell Translocation Gene 2 as a Potential Therapeutic Target in Ovarian Cancer.
Wang J, Li H, Wang L, Zhang J, Li M, Qiao L, Zhang J, Liu L, Zhang C, Gao J, Li W
Frontiers in oncology 2021;11:681250
Frontiers in oncology 2021;11:681250
The RNA-Binding Protein NELFE Promotes Gastric Cancer Growth and Metastasis Through E2F2.
Chen C, Zheng Q, Pan S, Chen W, Huang J, Cao Y, Tu Y, Li Z, Yu C, Jie Z
Frontiers in oncology 2021;11:677111
Frontiers in oncology 2021;11:677111
Long Non-Coding RNA LINC00467 Correlates to Poor Prognosis and Aggressiveness of Breast Cancer.
Zhang Y, Sun Y, Ding L, Shi W, Ding K, Zhu Y
Frontiers in oncology 2021;11:643394
Frontiers in oncology 2021;11:643394
N6-Methyladenosine Modification of LncRNA DUXAP9 Promotes Renal Cancer Cells Proliferation and Motility by Activating the PI3K/AKT Signaling Pathway.
Tan L, Tang Y, Li H, Li P, Ye Y, Cen J, Gui C, Luo J, Cao J, Wei J
Frontiers in oncology 2021;11:641833
Frontiers in oncology 2021;11:641833
Downregulation of GLYAT Facilitates Tumor Growth and Metastasis and Poor Clinical Outcomes Through the PI3K/AKT/Snail Pathway in Human Breast Cancer.
Tian X, Wu L, Jiang M, Zhang Z, Wu R, Miao J, Liu C, Gao S
Frontiers in oncology 2021;11:641399
Frontiers in oncology 2021;11:641399
MiR-454-3p Promotes Oxaliplatin Resistance by Targeting PTEN in Colorectal Cancer.
Qian XL, Zhou F, Xu S, Jiang J, Chen ZP, Wang SK, Zuo Y, Ni C
Frontiers in oncology 2021;11:638537
Frontiers in oncology 2021;11:638537
Asparagine Synthetase-Mediated l-Asparagine Metabolism Disorder Promotes the Perineural Invasion of Oral Squamous Cell Carcinoma.
Fu Y, Ding L, Yang X, Ding Z, Huang X, Zhang L, Chen S, Hu Q, Ni Y
Frontiers in oncology 2021;11:637226
Frontiers in oncology 2021;11:637226
Discovering and Characterizing of Survivin Dominant Negative Mutants With Stronger Pro-apoptotic Activity on Cancer Cells and CSCs.
Guo W, Ma X, Fu Y, Liu C, Liu Q, Hu F, Miao H, Zhang T, Liu Y, Han MH, You F, Yang Y, Zheng W
Frontiers in oncology 2021;11:635233
Frontiers in oncology 2021;11:635233
HOXA5 Is Recognized as a Prognostic-Related Biomarker and Promotes Glioma Progression Through Affecting Cell Cycle.
Ding F, Chen P, Bie P, Piao W, Cheng Q
Frontiers in oncology 2021;11:633430
Frontiers in oncology 2021;11:633430
TFEB Promotes Prostate Cancer Progression via Regulating ABCA2-Dependent Lysosomal Biogenesis.
Zhu X, Zhuo Y, Wu S, Chen Y, Ye J, Deng Y, Feng Y, Liu R, Cai S, Zou Z, Wang B, Wu CL, Zeng G, Zhong W
Frontiers in oncology 2021;11:632524
Frontiers in oncology 2021;11:632524
Identification of Hub Genes Associated With Sensitivity of 5-Fluorouracil Based Chemotherapy for Colorectal Cancer by Integrated Bioinformatics Analysis.
Wang Y, Wei Q, Chen Y, Long S, Yao Y, Fu K
Frontiers in oncology 2021;11:604315
Frontiers in oncology 2021;11:604315
IFN-γ facilitates liver fibrogenesis by CD161(+)CD4(+) T cells through a regenerative IL-23/IL-17 axis in chronic hepatitis B virus infection.
Li J, Cheng L, Jia H, Liu C, Wang S, Liu Y, Shen Y, Wu S, Meng F, Zheng B, Yang C, Jiang W
Clinical & translational immunology 2021;10(11):e1353
Clinical & translational immunology 2021;10(11):e1353
Epigallocatechin-3-gallate inhibits proliferation and triggers apoptosis in colon cancer via the hedgehog/phosphoinositide 3-kinase pathways.
Ding F, Yang S
Canadian journal of physiology and pharmacology 2021 Sep;99(9):910-920
Canadian journal of physiology and pharmacology 2021 Sep;99(9):910-920
SARS-CoV-2 ORF9b antagonizes type I and III interferons by targeting multiple components of the RIG-I/MDA-5-MAVS, TLR3-TRIF, and cGAS-STING signaling pathways.
Han L, Zhuang MW, Deng J, Zheng Y, Zhang J, Nan ML, Zhang XJ, Gao C, Wang PH
Journal of medical virology 2021 Sep;93(9):5376-5389
Journal of medical virology 2021 Sep;93(9):5376-5389
Subicular Caspase-1 Contributes to Pharmacoresistance in Temporal Lobe Epilepsy.
Xu C, Zhang S, Gong Y, Nao J, Shen Y, Tan B, Xu S, Cui S, Ruan Y, Wang S, Wang Y, Chen Z
Annals of neurology 2021 Sep;90(3):377-390
Annals of neurology 2021 Sep;90(3):377-390
Yangonin modulates lipid homeostasis, ameliorates cholestasis and cellular senescence in alcoholic liver disease via activating nuclear receptor FXR.
Kong L, Dong R, Huang K, Wang X, Wang D, Yue N, Wang C, Sun P, Gu J, Luo H, Liu K, Wu J, Sun H, Meng Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Sep;90:153629
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Sep;90:153629
Spindle and kinetochore-associated complex subunit 3 (SKA3) promotes stem cell-like properties of hepatocellular carcinoma cells through activating Notch signaling pathway.
Bai S, Chen W, Zheng M, Wang X, Peng W, Zhao Y, Wang Y, Xiong S, Cheng B
Annals of translational medicine 2021 Sep;9(17):1361
Annals of translational medicine 2021 Sep;9(17):1361
Actin-binding protein, IQGAP1, regulates LPS-induced RPMVECs hyperpermeability and ICAM-1 upregulation via Rap1/Src signalling pathway.
Zhang N, Wang G, Sun G
Cellular signalling 2021 Sep;85:110067
Cellular signalling 2021 Sep;85:110067
HOXA5 induces M2 macrophage polarization to attenuate carotid atherosclerosis by activating MED1.
Jing Y, Gao B, Han Z, Xin S
IUBMB life 2021 Sep;73(9):1142-1152
IUBMB life 2021 Sep;73(9):1142-1152
AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence.
Lee S, Karki R, Wang Y, Nguyen LN, Kalathur RC, Kanneganti TD
Nature 2021 Sep;597(7876):415-419
Nature 2021 Sep;597(7876):415-419
Disruption of Circadian Clocks Promotes Progression of Alzheimer's Disease in Diabetic Mice.
Huang J, Peng X, Fan R, Dong K, Shi X, Zhang S, Yu X, Yang Y
Molecular neurobiology 2021 Sep;58(9):4404-4412
Molecular neurobiology 2021 Sep;58(9):4404-4412
Postconditioning with Sevoflurane or Propofol Alleviates Lipopolysaccharide-Induced Neuroinflammation but Exerts Dissimilar Effects on the NR2B Subunit and Cognition.
Liu H, Chen B, Guo B, Deng X, Wang B, Dou X
Molecular neurobiology 2021 Sep;58(9):4251-4267
Molecular neurobiology 2021 Sep;58(9):4251-4267
Melatonin and doxorubicin synergistically enhance apoptosis via autophagy-dependent reduction of AMPKα1 transcription in human breast cancer cells.
Tran QH, Hoang DH, Song M, Choe W, Kang I, Kim SS, Ha J
Experimental & molecular medicine 2021 Sep;53(9):1413-1422
Experimental & molecular medicine 2021 Sep;53(9):1413-1422
Bruton's tyrosine kinase regulates macrophage‑induced inflammation in the diabetic kidney via NLRP3 inflammasome activation.
Zhao J, Chen J, Li YY, Xia LL, Wu YG
International journal of molecular medicine 2021 Sep;48(3)
International journal of molecular medicine 2021 Sep;48(3)
Environmental Microcystin exposure in underlying NAFLD-induced exacerbation of neuroinflammation, blood-brain barrier dysfunction, and neurodegeneration are NLRP3 and S100B dependent.
Mondal A, Saha P, Bose D, Chatterjee S, Seth RK, Xiao S, Porter DE, Brooks BW, Scott GI, Nagarkatti M, Nagarkatti P, Chatterjee S
Toxicology 2021 Sep;461:152901
Toxicology 2021 Sep;461:152901
Spata2 Knockdown Exacerbates Brain Inflammation via NF-κB/P38MAPK Signaling and NLRP3 Inflammasome Activation in Cerebral Ischemia/Reperfusion Rats.
Ren Y, Jiang J, Jiang W, Zhou X, Lu W, Wang J, Luo Y
Neurochemical research 2021 Sep;46(9):2262-2275
Neurochemical research 2021 Sep;46(9):2262-2275
Long noncoding RNA ANRIL knockdown attenuates neuroinflammation following ischemic stroke via suppressing the expression of NF-κB in vitro and in vivo.
Deng L, Guo Y, Liu J, Chen S, Wang X, Zhao H, Zuo T, Hu Q, Dong Z
Neurological research 2021 Sep;43(9):767-777
Neurological research 2021 Sep;43(9):767-777
KDELR2 promotes breast cancer proliferation via HDAC3-mediated cell cycle progression.
Wei H, Ma W, Lu X, Liu H, Lin K, Wang Y, Ye Z, Sun L, Huang Z, Pan T, Zhou Z, Cheng EY, Zhang H, Gao P, Zhong X
Cancer communications (London, England) 2021 Sep;41(9):904-920
Cancer communications (London, England) 2021 Sep;41(9):904-920
Gastrodin protects against high glucose-induced cardiomyocyte toxicity via GSK-3β-mediated nuclear translocation of Nrf2.
Dong Z, Bian L, Wang YL, Sun LM
Human & experimental toxicology 2021 Sep;40(9):1584-1597
Human & experimental toxicology 2021 Sep;40(9):1584-1597
An Antioxidant Sesquiterpene Inhibits Osteoclastogenesis Via Blocking IPMK/TRAF6 and Counteracts OVX-Induced Osteoporosis in Mice.
Wang S, Ma Q, Xie Z, Shen Y, Zheng B, Jiang C, Yuan P, An Q, Fan S, Jie Z
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2021 Sep;36(9):1850-1865
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2021 Sep;36(9):1850-1865
Long non-coding RNA DUXAP9 promotes hepatocellular carcinoma cell stemness via directly interacting with sox9.
Zeng R, Wang C, Wang W, Wang S
Environmental toxicology 2021 Sep;36(9):1793-1801
Environmental toxicology 2021 Sep;36(9):1793-1801
Compound essential oils relieve oxidative stress caused by PM(2) (.5) exposure by inhibiting autophagy through the AMPK/mTOR pathway.
Ren F, Xu X, Xu J, Mei Y, Zhang J, Wang X, Li F
Environmental toxicology 2021 Sep;36(9):1765-1774
Environmental toxicology 2021 Sep;36(9):1765-1774
CTR9-mediated JAK2/STAT3 pathway promotes the proliferation, migration, and invasion of human glioma cells.
Xu Y, Chen J, He G, Zhang Y
Journal of clinical laboratory analysis 2021 Sep;35(9):e23943
Journal of clinical laboratory analysis 2021 Sep;35(9):e23943
MiR-100-5p regulates cardiac hypertrophy through activation of autophagy by targeting mTOR.
Zeng J, Wang L, Zhao J, Zheng Z, Peng J, Zhang W, Wen T, Nie J, Ding L, Yi D
Human cell 2021 Sep;34(5):1388-1397
Human cell 2021 Sep;34(5):1388-1397
Bone marrow mesenchymal stem cell-derived exosomes induce the Th17/Treg imbalance in immune thrombocytopenia through miR-146a-5p/IRAK1 axis.
He Y, Ji D, Lu W, Li F, Huang X, Huang R, Chen G
Human cell 2021 Sep;34(5):1360-1374
Human cell 2021 Sep;34(5):1360-1374
Bovine viral diarrhea virus NS4B protein interacts with 2CARD of MDA5 domain and negatively regulates the RLR-mediated IFN-β production.
Shan Y, Tong Z, Jinzhu M, Yu L, Zecai Z, Chenhua W, Wenjing H, Siyu L, Nannan C, Siyu S, Tongtong B, Jiang H, Biaohui B, Xin J, Yulong Z, Zhanbo Z
Virus research 2021 Sep;302:198471
Virus research 2021 Sep;302:198471
Docosahexaenoic acid activates the Nrf2 signaling pathway to alleviate impairment of spleen cellular immunity in intrauterine growth restricted rat pups.
Jiang W, Wan L, Chen P, Lu W
Saudi journal of biological sciences 2021 Sep;28(9):4987-4993
Saudi journal of biological sciences 2021 Sep;28(9):4987-4993
Cinnabar protects serum-nutrient starvation induced apoptosis by improving intracellular oxidative stress and inhibiting the expression of CHOP and PERK.
Ma HH, Ding YN, Wang A, Li X, Wang Y, Shi FG, Lu YF
Biochemistry and biophysics reports 2021 Sep;27:101055
Biochemistry and biophysics reports 2021 Sep;27:101055
miR-29c-3p regulates TET2 expression and inhibits autophagy process in Parkinson's disease models.
Wang R, Yao J, Gong F, Chen S, He Y, Hu C, Li C
Genes to cells : devoted to molecular & cellular mechanisms 2021 Sep;26(9):684-697
Genes to cells : devoted to molecular & cellular mechanisms 2021 Sep;26(9):684-697
DNM3OS regulates GAPDH expression and influences the molecular pathogenesis of Huntington's disease.
Dong X, Cong S
Journal of cellular and molecular medicine 2021 Sep;25(18):9066-9071
Journal of cellular and molecular medicine 2021 Sep;25(18):9066-9071
Exogenous H(2) S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
Zhang L, Jiang X, Liu N, Li M, Kang J, Chen L, Tang J, Dong S, Lu F, Zhang W
Journal of cellular and molecular medicine 2021 Sep;25(17):8201-8214
Journal of cellular and molecular medicine 2021 Sep;25(17):8201-8214
Expression of TCF3 in Wilms' tumor and its regulatory role in kidney tumor cell viability, migration and apoptosis in vitro.
Zhou N, Yan B, Ma J, Jiang H, Li L, Tang H, Ji F, Yao Z
Molecular medicine reports 2021 Sep;24(3)
Molecular medicine reports 2021 Sep;24(3)
Identification and validation of EPHX2 as a prognostic biomarker in hepatocellular carcinoma.
Zhan K, Bai Y, Liao S, Chen H, Kuang L, Luo Q, Lv L, Qiu L, Mei Z
Molecular medicine reports 2021 Sep;24(3)
Molecular medicine reports 2021 Sep;24(3)
Salusin‑β participates in high glucose‑induced HK‑2 cell ferroptosis in a Nrf‑2‑dependent manner.
Wang WJ, Jiang X, Gao CC, Chen ZW
Molecular medicine reports 2021 Sep;24(3)
Molecular medicine reports 2021 Sep;24(3)
Lack of Mof reduces acute liver injury by enhancing transcriptional activation of Igf1.
Wang M, Liu H, Zhang X, Zhao W, Li D, Xu C, Wu Z, Xie F, Li X
Journal of cellular physiology 2021 Sep;236(9):6559-6570
Journal of cellular physiology 2021 Sep;236(9):6559-6570
PKC-β/Alox5 axis activation promotes Bcr-Abl-independent TKI-resistance in chronic myeloid leukemia.
Ma D, Liu P, Wang P, Zhou Z, Fang Q, Wang J
Journal of cellular physiology 2021 Sep;236(9):6312-6327
Journal of cellular physiology 2021 Sep;236(9):6312-6327
Propofol inhibited gastric cancer proliferation via the hsa-miR-328-3p/STAT3 pathway.
Bai ZM, Li XF, Yang Y, Yang YF, Lv DR, Tang LL
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2021 Sep;23(9):1866-1873
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2021 Sep;23(9):1866-1873
The piRNA pathway is essential for generating functional oocytes in golden hamsters.
Zhang H, Zhang F, Chen Q, Li M, Lv X, Xiao Y, Zhang Z, Hou L, Lai Y, Zhang Y, Zhang A, Gao S, Fu H, Xiao W, Zhou J, Diao F, Shi A, Su YQ, Zeng W, Wu L, Li J
Nature cell biology 2021 Sep;23(9):1013-1022
Nature cell biology 2021 Sep;23(9):1013-1022
RNA N(6) -methyladenosine modification suppresses replication of rice black streaked dwarf virus and is associated with virus persistence in its insect vector.
Tian S, Wu N, Zhang L, Wang X
Molecular plant pathology 2021 Sep;22(9):1070-1081
Molecular plant pathology 2021 Sep;22(9):1070-1081
Autophagy promotes invadopodia formation in human ovarian cancer cells via the p62-extracellular signal-regulated kinase 1/2 pathway.
Zhou Z, Zhao J, Liu Y, Yan X, Sun H, Xia M, Su J
Experimental and therapeutic medicine 2021 Sep;22(3):952
Experimental and therapeutic medicine 2021 Sep;22(3):952
Low-dose repeated exposure to chemical surfactant impairs corneal epithelium: When personal cleaning products entering the eye.
Wu J, Wu T, Zheng S, Huang Y, Wang L
Experimental eye research 2021 Sep;210:108696
Experimental eye research 2021 Sep;210:108696
Hsa_circ_0006232 promotes laryngeal squamous cell cancer progression through FUS-mediated EZH2 stabilization.
Wu T, Wang G, Zeng X, Sun Z, Li S, Wang W, Yu B
Cell cycle (Georgetown, Tex.) 2021 Sep;20(18):1799-1811
Cell cycle (Georgetown, Tex.) 2021 Sep;20(18):1799-1811
Total Flavonoids of Engelhardia roxburghiana Wall. Leaves Alleviated Foam Cells Formation through AKT/mTOR-Mediated Autophagy in the Progression of Atherosclerosis.
Wei J, Huang L, Li D, He J, Li Y, He F, Fang W, Wei G
Chemistry & biodiversity 2021 Sep;18(9):e2100308
Chemistry & biodiversity 2021 Sep;18(9):e2100308
High mobility group box 1 mediates inflammatory response of astrocytes via cyclooxygenase 2/prostaglandin E2 signaling following spinal cord injury.
Song HH, Song TC, Yang T, Sun CS, He BQ, Li H, Wang YJ, Li Y, Wu H, Hu YM, Wang YJ
Neural regeneration research 2021 Sep;16(9):1848-1855
Neural regeneration research 2021 Sep;16(9):1848-1855
Ruyiping extract reduces lung metastasis in triple negative breast cancer by regulating macrophage polarization.
Yang R, Xie Y, Li Q, Ye Y, Shi Y, Zhao X, Wu C, Xu Y, Wang R, Zhang Y, Yang X, Han X, Liu S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Sep;141:111883
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Sep;141:111883
Quadruple-editing of the MAPK and PI3K pathways effectively blocks the progression of KRAS-mutated colorectal cancer cells.
Wang Z, Kang B, Gao Q, Huang L, Di J, Fan Y, Yu J, Jiang B, Gao F, Wang D, Sun H, Gu Y, Li J, Su X
Cancer science 2021 Sep;112(9):3895-3910
Cancer science 2021 Sep;112(9):3895-3910
METTL14 promotes glomerular endothelial cell injury and diabetic nephropathy via m6A modification of α-klotho.
Li M, Deng L, Xu G
Molecular medicine (Cambridge, Mass.) 2021 Sep 9;27(1):106
Molecular medicine (Cambridge, Mass.) 2021 Sep 9;27(1):106
Genomic and epigenomic evolution of acquired resistance to combination therapy in esophageal squamous cell carcinoma.
Min Q, Wang Y, Wu Q, Li X, Teng H, Fan J, Cao Y, Fan P, Zhan Q
JCI insight 2021 Sep 8;6(17)
JCI insight 2021 Sep 8;6(17)
Viral targeting of glioblastoma stem cells with patient-specific genetic and post-translational p53 deregulations.
Gil-Ranedo J, Gallego-García C, Almendral JM
Cell reports 2021 Sep 7;36(10):109673
Cell reports 2021 Sep 7;36(10):109673
A pair of long intergenic non-coding RNA LINC00887 variants act antagonistically to control Carbonic Anhydrase IX transcription upon hypoxia in tongue squamous carcinoma progression.
Shen T, Xia W, Min S, Yang Z, Cheng L, Wang W, Zhan Q, Shao F, Zhang X, Wang Z, Zhang Y, Shen G, Zhang H, Wu LL, Yu GY, Kong QP, Wang X
BMC biology 2021 Sep 7;19(1):192
BMC biology 2021 Sep 7;19(1):192
Cannabidiol Effectively Promoted Cell Death in Bladder Cancer and the Improved Intravesical Adhesion Drugs Delivery Strategy Could Be Better Used for Treatment.
Chen S, Deng C, Zheng W, Li S, Liu Y, Zhang T, Zhang C, Fu Y, Miao H, Ren F, Ma X
Pharmaceutics 2021 Sep 7;13(9)
Pharmaceutics 2021 Sep 7;13(9)
ACLY ubiquitination by CUL3-KLHL25 induces the reprogramming of fatty acid metabolism to facilitate iTreg differentiation.
Tian M, Hao F, Jin X, Sun X, Jiang Y, Wang Y, Li D, Chang T, Zou Y, Peng P, Xia C, Liu J, Li Y, Wang P, Feng Y, Wei M
eLife 2021 Sep 7;10
eLife 2021 Sep 7;10
Suppressors of cytokine signaling 1 protein in a regenerative model of the Gekko japonicus spinal cord.
He B, Wang W, Sun C, Yang T, Li H, Chen X, Liang H, Song H, Wang Y, Wang Y
Journal of integrative neuroscience 2021 Sep 30;20(3):585-594
Journal of integrative neuroscience 2021 Sep 30;20(3):585-594
Stimulation of ROS Generation by Extract of Warburgia ugandensis Leading to G(0)/G(1) Cell Cycle Arrest and Antiproliferation in A549 Cells.
Zhang YL, Chen GL, Liu Y, Zhuang XC, Guo MQ
Antioxidants (Basel, Switzerland) 2021 Sep 30;10(10)
Antioxidants (Basel, Switzerland) 2021 Sep 30;10(10)
Identification and Characterization of Eimeria tenella Microneme Protein (EtMIC8).
Zhao N, Ming S, Sun L, Wang B, Li H, Zhang X, Zhao X
Microbiology spectrum 2021 Sep 3;9(1):e0022821
Microbiology spectrum 2021 Sep 3;9(1):e0022821
HIF-1α/JMJD1A signaling regulates inflammation and oxidative stress following hyperglycemia and hypoxia-induced vascular cell injury.
Zhao M, Wang S, Zuo A, Zhang J, Wen W, Jiang W, Chen H, Liang D, Sun J, Wang M
Cellular & molecular biology letters 2021 Sep 3;26(1):40
Cellular & molecular biology letters 2021 Sep 3;26(1):40
Adipose expression of CREB3L3 modulates body weight during obesity.
McCann MA, Li Y, Muñoz M, Gil V, Qiang G, Cordoba-Chacon J, Blüher M, Duncan S, Liew CW
Scientific reports 2021 Sep 29;11(1):19400
Scientific reports 2021 Sep 29;11(1):19400
Exosomal microRNA-588 from M2 polarized macrophages contributes to cisplatin resistance of gastric cancer cells.
Cui HY, Rong JS, Chen J, Guo J, Zhu JQ, Ruan M, Zuo RR, Zhang SS, Qi JM, Zhang BH
World journal of gastroenterology 2021 Sep 28;27(36):6079-6092
World journal of gastroenterology 2021 Sep 28;27(36):6079-6092
Dual Inhibition of Endoplasmic Reticulum Stress and Oxidation Stress Manipulates the Polarization of Macrophages under Hypoxia to Sensitize Immunotherapy.
Jiang M, Li X, Zhang J, Lu Y, Shi Y, Zhu C, Liu Y, Qin B, Luo Z, Du Y, Luo L, Peng L, You J
ACS nano 2021 Sep 28;15(9):14522-14534
ACS nano 2021 Sep 28;15(9):14522-14534
Identification of genes and pathways leading to metastasis and poor prognosis in melanoma.
Zhang X, Wang W, Wang Y, Jiang G
Aging 2021 Sep 28;13(18):22474-22489
Aging 2021 Sep 28;13(18):22474-22489
The Ginsenoside Rg(1) Rescues Mitochondrial Disorders in Aristolochic Acid-Induced Nephropathic Mice.
Chou CK, Huang YS, Lin PY, Imai K, Chen SM, Lee JA
Life (Basel, Switzerland) 2021 Sep 27;11(10)
Life (Basel, Switzerland) 2021 Sep 27;11(10)
Anti-osteosarcoma effect of antiserum against cross antigen TPD52 between osteosarcoma and Trichinella spiralis.
Yue TT, Zhang N, Li JH, Lu XY, Wang XC, Li X, Zhang HB, Cheng SQ, Wang BB, Gong PT, Zhang XC
Parasites & vectors 2021 Sep 26;14(1):498
Parasites & vectors 2021 Sep 26;14(1):498
MEST promotes lung cancer invasion and metastasis by interacting with VCP to activate NF-κB signaling.
Wang Y, Zhang J, Li YJ, Yu NN, Liu WT, Liang JZ, Xu WW, Sun ZH, Li B, He QY
Journal of experimental & clinical cancer research : CR 2021 Sep 24;40(1):301
Journal of experimental & clinical cancer research : CR 2021 Sep 24;40(1):301
Potent Inhibition of HIF1α and p300 Interaction by a Constrained Peptide Derived from CITED2.
Qin X, Chen H, Tu L, Ma Y, Liu N, Zhang H, Li D, Riedl B, Bierer D, Yin F, Li Z
Journal of medicinal chemistry 2021 Sep 23;64(18):13693-13703
Journal of medicinal chemistry 2021 Sep 23;64(18):13693-13703
Discovery of a Potent Glutathione Peroxidase 4 Inhibitor as a Selective Ferroptosis Inducer.
Xu C, Xiao Z, Wang J, Lai H, Zhang T, Guan Z, Xia M, Chen M, Ren L, He Y, Gao Y, Zhao C
Journal of medicinal chemistry 2021 Sep 23;64(18):13312-13326
Journal of medicinal chemistry 2021 Sep 23;64(18):13312-13326
Perinatal low-dose bisphenol AF exposure impairs synaptic plasticity and cognitive function of adult offspring in a sex-dependent manner.
Zhang C, Wu XC, Li S, Dou LJ, Zhou L, Wang FH, Ma K, Huang D, Pan Y, Gu JJ, Cao JY, Wang H, Hao JH
The Science of the total environment 2021 Sep 20;788:147918
The Science of the total environment 2021 Sep 20;788:147918
Genistein exhibits therapeutic potential for PCOS mice via the ER-Nrf2-Foxo1-ROS pathway.
Luo M, Zheng LW, Wang YS, Huang JC, Yang ZQ, Yue ZP, Guo B
Food & function 2021 Sep 20;12(18):8800-8811
Food & function 2021 Sep 20;12(18):8800-8811
Isonicotinylation is a histone mark induced by the anti-tuberculosis first-line drug isoniazid.
Jiang Y, Li Y, Liu C, Zhang L, Lv D, Weng Y, Cheng Z, Chen X, Zhan J, Zhang H
Nature communications 2021 Sep 20;12(1):5548
Nature communications 2021 Sep 20;12(1):5548
β-adrenergic receptor inhibition enhances oncolytic herpes virus propagation through STAT3 activation in gastric cancer.
Hu J, Lu R, Zhang Y, Li W, Hu Q, Chen C, Liu Z, Zhang W, Chen L, Xu R, Luo J, McLeod HL, He Y
Cell & bioscience 2021 Sep 20;11(1):174
Cell & bioscience 2021 Sep 20;11(1):174
Ultramicronized Palmitoylethanolamide Inhibits NLRP3 Inflammasome Expression and Pro-Inflammatory Response Activated by SARS-CoV-2 Spike Protein in Cultured Murine Alveolar Macrophages.
Del Re A, Corpetti C, Pesce M, Seguella L, Steardo L, Palenca I, Rurgo S, De Conno B, Sarnelli G, Esposito G
Metabolites 2021 Sep 2;11(9)
Metabolites 2021 Sep 2;11(9)
RIOK2 Inhibitor NSC139021 Exerts Anti-Tumor Effects on Glioblastoma via Inducing Skp2-Mediated Cell Cycle Arrest and Apoptosis.
Yu M, Hu X, Yan J, Wang Y, Lu F, Chang J
Biomedicines 2021 Sep 17;9(9)
Biomedicines 2021 Sep 17;9(9)
Lactobacillus johnsonii L531 Alleviates the Damage Caused by Salmonella Typhimurium via Inhibiting TLR4, NF-κB, and NLRP3 Inflammasome Signaling Pathways.
Chen S, Li Y, Chu B, Yuan L, Liu N, Zhu Y, Wang J
Microorganisms 2021 Sep 17;9(9)
Microorganisms 2021 Sep 17;9(9)
KIF15 upregulation promotes leiomyosarcoma cell growth via promoting USP15-mediated DEK deubiquitylation.
Ge W, Chen Y, Guo Y, Zhao D, Mu L, Zhang K, Zhuo W
Biochemical and biophysical research communications 2021 Sep 17;570:117-124
Biochemical and biophysical research communications 2021 Sep 17;570:117-124
UBE2S promotes the progression and Olaparib resistance of ovarian cancer through Wnt/β-catenin signaling pathway.
Hu W, Li M, Chen Y, Gu X
Journal of ovarian research 2021 Sep 17;14(1):121
Journal of ovarian research 2021 Sep 17;14(1):121
HSF1 is involved in suppressing A1 phenotype conversion of astrocytes following spinal cord injury in rats.
Li L, Li Y, He B, Li H, Ji H, Wang Y, Zhu Z, Hu Y, Zhou Y, Yang T, Sun C, Yuan Y, Wang Y
Journal of neuroinflammation 2021 Sep 16;18(1):205
Journal of neuroinflammation 2021 Sep 16;18(1):205
MiR-200c-3p promotes ox-LDL-induced endothelial to mesenchymal transition in human umbilical vein endothelial cells through SMAD7/YAP pathway.
Mao Y, Jiang L
The journal of physiological sciences : JPS 2021 Sep 15;71(1):30
The journal of physiological sciences : JPS 2021 Sep 15;71(1):30
Harmine-inspired design and synthesis of benzo[d]imidazo[2,1-b]thiazole derivatives bearing 1,3,4-oxadiazole moiety as potential tumor suppressors.
Zhao T, Yang Y, Yang J, Cui Y, Cao Z, Zuo D, Zhai X
Bioorganic & medicinal chemistry 2021 Sep 15;46:116367
Bioorganic & medicinal chemistry 2021 Sep 15;46:116367
Hypoxia increases KIAA1199/CEMIP expression and enhances cell migration in pancreatic cancer.
Oba T, Sato N, Adachi Y, Amaike T, Kudo Y, Koga A, Kohi S, Hirata K
Scientific reports 2021 Sep 14;11(1):18193
Scientific reports 2021 Sep 14;11(1):18193
Genetically variant human pluripotent stem cells selectively eliminate wild-type counterparts through YAP-mediated cell competition.
Price CJ, Stavish D, Gokhale PJ, Stevenson BA, Sargeant S, Lacey J, Rodriguez TA, Barbaric I
Developmental cell 2021 Sep 13;56(17):2455-2470.e10
Developmental cell 2021 Sep 13;56(17):2455-2470.e10
Ketamine ameliorates depressive-like behaviors in mice through increasing glucose uptake regulated by the ERK/GLUT3 signaling pathway.
Ouyang X, Wang Z, Luo M, Wang M, Liu X, Chen J, Feng J, Jia J, Wang X
Scientific reports 2021 Sep 13;11(1):18181
Scientific reports 2021 Sep 13;11(1):18181
A standardized extract of Asparagus officinalis stem improves HSP70-mediated redox balance and cell functions in bovine cumulus-granulosa cells.
Ho KT, Homma K, Takanari J, Bai H, Kawahara M, Nguyen KTK, Takahashi M
Scientific reports 2021 Sep 13;11(1):18175
Scientific reports 2021 Sep 13;11(1):18175
2,5-dimethyl celecoxib induces apoptosis and autophagy via activation of ROS/JNK axis in nasopharyngeal carcinoma cells.
Tan T, Fu X, Qu J, Zhang M, Chen H, Wang Y, Wang B, Li J, Liu J, Liu P
Aging 2021 Sep 12;13(17):21483-21496
Aging 2021 Sep 12;13(17):21483-21496
Defining the Cholesterol Lowering Mechanism of Bergamot (Citrus bergamia) Extract in HepG2 and Caco-2 Cells.
Huang Y, Tocmo R, Nauman MC, Haughan MA, Johnson JJ
Nutrients 2021 Sep 10;13(9)
Nutrients 2021 Sep 10;13(9)
Targeting chromosome trisomy for chromosome editing.
Abe T, Suzuki Y, Ikeya T, Hirota K
Scientific reports 2021 Sep 10;11(1):18054
Scientific reports 2021 Sep 10;11(1):18054
Baicalein Enhances the Effect of Acarbose on the Improvement of Nonalcoholic Fatty Liver Disease Associated with Prediabetes via the Inhibition of De Novo Lipogenesis.
Xing Y, Ren X, Li X, Sui L, Shi X, Sun Y, Quan C, Xiu Z, Dong Y
Journal of agricultural and food chemistry 2021 Sep 1;69(34):9822-9836
Journal of agricultural and food chemistry 2021 Sep 1;69(34):9822-9836
H(2)S alleviates aortic aneurysm and dissection: Crosstalk between transforming growth factor 1 signaling and NLRP3 inflammasome.
Cui J, Xu G, Bian F
International journal of cardiology 2021 Sep 1;338:215-225
International journal of cardiology 2021 Sep 1;338:215-225
Silica nanoparticles inhibiting the differentiation of round spermatid and chromatin remodeling of haploid period via MIWI in mice.
Liu J, Li X, Zhou G, Zhang Y, Sang Y, Wang J, Li Y, Ge W, Sun Z, Zhou X
Environmental pollution (Barking, Essex : 1987) 2021 Sep 1;284:117446
Environmental pollution (Barking, Essex : 1987) 2021 Sep 1;284:117446
LncAY controls BMI1 expression and activates BMI1/Wnt/β-catenin signaling axis in hepatocellular carcinoma.
Chen MH, Fu LS, Zhang F, Yang Y, Wu XZ
Life sciences 2021 Sep 1;280:119748
Life sciences 2021 Sep 1;280:119748
Sitagliptin attenuates endothelial dysfunction independent of its blood glucose controlling effect.
Chang XM, Xiao F, Pan Q, Wang XX, Guo LX
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2021 Sep 1;25(5):425-437
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2021 Sep 1;25(5):425-437
LncRNA OIP5-AS1 inhibits ferroptosis in prostate cancer with long-term cadmium exposure through miR-128-3p/SLC7A11 signaling.
Zhang Y, Guo S, Wang S, Li X, Hou D, Li H, Wang L, Xu Y, Ma B, Wang H, Jiang X
Ecotoxicology and environmental safety 2021 Sep 1;220:112376
Ecotoxicology and environmental safety 2021 Sep 1;220:112376
Yeast Shells Encapsulating Adjuvant AS04 as an Antigen Delivery System for a Novel Vaccine against Toxoplasma Gondii.
Zhu L, Lei Z, Xia X, Zhang Y, Chen Y, Wang B, Li J, Li G, Yang G, Cao G, Yin Z
ACS applied materials & interfaces 2021 Sep 1;13(34):40415-40428
ACS applied materials & interfaces 2021 Sep 1;13(34):40415-40428
Radiation-Induced Autophagy in Human Pancreatic Cancer Cells is Critically Dependent on G2 Checkpoint Activation: A Mechanism of Radioresistance in Pancreatic Cancer.
Suzuki M, Anko M, Ohara M, Matsumoto KI, Hasegawa S
International journal of radiation oncology, biology, physics 2021 Sep 1;111(1):260-271
International journal of radiation oncology, biology, physics 2021 Sep 1;111(1):260-271
Exosomes derived from induced pluripotent stem cells suppresses M2-type macrophages during pulmonary fibrosis via miR-302a-3p/TET1 axis.
Zhou Y, Gao Y, Zhang W, Chen Y, Jin M, Yang Z
International immunopharmacology 2021 Oct;99:108075
International immunopharmacology 2021 Oct;99:108075
JNK inhibition alleviates delayed neurocognitive recovery after surgery by limiting microglia pyroptosis.
He J, Liu T, Li Y, Mi X, Han D, Yang N, Chen L, Li Y, Hong J, Kuang C, Yuan Y, Cao Y, Han Y, Shi C, Li Z, Guo X
International immunopharmacology 2021 Oct;99:107962
International immunopharmacology 2021 Oct;99:107962
Thymus quinquecostatus Celak. ameliorates cerebral ischemia-reperfusion injury via dual antioxidant actions: Activating Keap1/Nrf2/HO-1 signaling pathway and directly scavenging ROS.
Fan S, Liu X, Wang Y, Ren X, Liu Y, Dong Y, Fan Q, Wei J, Ma J, Yu A, Song R, Sui H, Shen M, Fang F, Xia Q, She G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Oct;91:153673
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Oct;91:153673
Lactobacillus casei relieves liver injury by regulating immunity and suppression of the enterogenic endotoxin-induced inflammatory response in rats cotreated with alcohol and iron.
Li X, Han J, Liu Y, Liang H
Food science & nutrition 2021 Oct;9(10):5391-5401
Food science & nutrition 2021 Oct;9(10):5391-5401
Characteristics and clinical significance of polyploid giant cancer cells in laryngeal carcinoma.
Liu HT, Xia T, You YW, Zhang QC, Ni HS, Liu YF, Liu YR, Xu YQ, You B, Zhang ZX
Laryngoscope investigative otolaryngology 2021 Oct;6(5):1228-1234
Laryngoscope investigative otolaryngology 2021 Oct;6(5):1228-1234
SETD3 Downregulation Mediates PTEN Upregulation-Induced Ischemic Neuronal Death Through Suppression of Actin Polymerization and Mitochondrial Function.
Xu X, Cui Y, Li C, Wang Y, Cheng J, Chen S, Sun J, Ren J, Yao X, Gao J, Huang X, Wan Q, Wang Q
Molecular neurobiology 2021 Oct;58(10):4906-4920
Molecular neurobiology 2021 Oct;58(10):4906-4920
Systematic screening identifies a TEAD4-S100A13 axis modulating cisplatin sensitivity of oral squamous cell carcinoma cells.
Li R, Li W, He F, Zhang M, Luo H, Tang H
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2021 Oct;50(9):882-890
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2021 Oct;50(9):882-890
Alpha-ketoglutarate ameliorates pressure overload-induced chronic cardiac dysfunction in mice.
An D, Zeng Q, Zhang P, Ma Z, Zhang H, Liu Z, Li J, Ren H, Xu D
Redox biology 2021 Oct;46:102088
Redox biology 2021 Oct;46:102088
CTHRC1 Knockdown Promotes Inflammatory Responses Partially by p38 MAPK Activation in Human Periodontal Ligament Cells.
Guo Y, Jiang C, Yao S, Ma L, Zhang H, Wang X, Xu S, Cao Z
Inflammation 2021 Oct;44(5):1831-1842
Inflammation 2021 Oct;44(5):1831-1842
Interleukin-38 Suppresses Cell Migration and Proliferation and Promotes Apoptosis of Colorectal Cancer Cell Through Negatively Regulating Extracellular Signal-Regulated Kinases Signaling.
Huang L, Zhang H, Zhao D, Hu H, Lu Z
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2021 Oct;41(10):375-384
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2021 Oct;41(10):375-384
High-mobility group AT-Hook 1 mediates the role of nuclear factor I/X in osteogenic differentiation through activating canonical Wnt signaling.
Wu X, Wang X, Shan L, Zhou J, Zhang X, Zhu E, Yuan H, Wang B
Stem cells (Dayton, Ohio) 2021 Oct;39(10):1349-1361
Stem cells (Dayton, Ohio) 2021 Oct;39(10):1349-1361
Autographa Californica Multiple Nucleopolyhedrovirus orf13 Is Required for Efficient Nuclear Egress of Nucleocapsids.
Chen X, Yang X, Lei C, Qin F, Sun X, Hu J
Virologica Sinica 2021 Oct;36(5):968-980
Virologica Sinica 2021 Oct;36(5):968-980
An enzyme-responsive Gp1a-hydrogel for skin wound healing.
Zhao C, Dong Y, Liu J, Cai H, Li Z, Sun X, Yin W, Ma J, Liu H, Li S
Journal of biomaterials applications 2021 Oct;36(4):714-721
Journal of biomaterials applications 2021 Oct;36(4):714-721
Imbalanced inflammatory response in subchronic arsenic-induced liver injury and the protective effects of Ginkgo biloba extract in rats: Potential role of cytokines mediated cell-cell interactions.
Dong L, Liu Y, Wang D, Zhu K, Zou Z, Zhang A
Environmental toxicology 2021 Oct;36(10):2073-2092
Environmental toxicology 2021 Oct;36(10):2073-2092
5-IP(7) is a GPCR messenger mediating neural control of synaptotagmin-dependent insulin exocytosis and glucose homeostasis.
Zhang X, Li N, Zhang J, Zhang Y, Yang X, Luo Y, Zhang B, Xu Z, Zhu Z, Yang X, Yan Y, Lin B, Wang S, Chen D, Ye C, Ding Y, Lou M, Wu Q, Hou Z, Zhang K, Liang Z, Wei A, Wang B, Wang C, Jiang N, Zhang W, Xiao G, Ma C, Ren Y, Qi X, Han W, Wang C, Rao F
Nature metabolism 2021 Oct;3(10):1400-1414
Nature metabolism 2021 Oct;3(10):1400-1414
Dynamin-related protein 1 regulates substrate oxidation in skeletal muscle by stabilizing cellular and mitochondrial calcium dynamics.
King WT, Axelrod CL, Zunica ERM, Noland RC, Davuluri G, Fujioka H, Tandler B, Pergola K, Hermann GE, Rogers RC, López-Domènech S, Dantas WS, Stadler K, Hoppel CL, Kirwan JP
The Journal of biological chemistry 2021 Oct;297(4):101196
The Journal of biological chemistry 2021 Oct;297(4):101196
Arsenic Trioxide Combining Leflunomide Activates Nrf2-ARE-HO-1 Signaling Pathway and Protects Heart Xenografts.
Wang TD, Xu SL, Yu ZY, Ni SB, Zhang C, Jiao ZX
Chinese journal of integrative medicine 2021 Oct;27(10):760-766
Chinese journal of integrative medicine 2021 Oct;27(10):760-766
MicroRNA ssc-miR-124a exhibits antiviral activity against porcine reproductive and respiratory syndrome virus via suppression of host genes CD163.
Li N, Huang K, Chen Y, Huang Z, Zhang Y, Leng C, Liu Y, Shi J, Xiao S, Yao L
Veterinary microbiology 2021 Oct;261:109216
Veterinary microbiology 2021 Oct;261:109216
TRIM21 negatively regulates Corynebacterium pseudotuberculosis-induced inflammation and is critical for the survival of C. pseudotuberculosis infected C57BL6 mice.
Tan J, Yi W, Wang Z, Ye C, Tian S, Li X, Zou A, Zhao X, Yuan Y, Wang X, Hu S, Zhou Z
Veterinary microbiology 2021 Oct;261:109209
Veterinary microbiology 2021 Oct;261:109209
Reactive oxygen species induced by uric acid promote NRK‑52E cell apoptosis through the NEK7‑NLRP3 signaling pathway.
Li D, Wang L, Ou J, Wang C, Zhou J, Lu L, Wu Y, Gao J
Molecular medicine reports 2021 Oct;24(4)
Molecular medicine reports 2021 Oct;24(4)
Hsa_circ_0004058 inhibits apoptosis of SRA01/04 cells by promoting autophagy via miR-186/ATG7 axis.
Wang Y, Wu Z, Huang Y, Zhang Y
Experimental eye research 2021 Oct;211:108721
Experimental eye research 2021 Oct;211:108721
Advanced Maternal Age-associated SIRT1 Deficiency Compromises Trophoblast Epithelial-Mesenchymal Transition through an Increase in Vimentin Acetylation.
Xiong L, Ye X, Chen Z, Fu H, Li S, Xu P, Yu J, Wen L, Gao R, Fu Y, Qi H, Kilby MD, Saffery R, Baker PN, Tong C
Aging cell 2021 Oct;20(10):e13491
Aging cell 2021 Oct;20(10):e13491
Activation of angiotensin-converting enzyme 2/angiotensin (1-7)/mas receptor axis triggers autophagy and suppresses microglia proinflammatory polarization via forkhead box class O1 signaling.
Dang R, Yang M, Cui C, Wang C, Zhang W, Geng C, Han W, Jiang P
Aging cell 2021 Oct;20(10):e13480
Aging cell 2021 Oct;20(10):e13480
Peptides derived from viral glycoprotein Gc Inhibit infection of severe fever with thrombocytopenia syndrome virus.
Gao C, Yu Y, Wen C, Li Z, Sun M, Gao S, Lin S, Wang S, Zou P, Xing Z
Antiviral research 2021 Oct;194:105164
Antiviral research 2021 Oct;194:105164
RSL3 enhances the antitumor effect of cisplatin on prostate cancer cells via causing glycolysis dysfunction.
Li M, Chen X, Wang X, Wei X, Wang D, Liu X, Xu L, Batu W, Li Y, Guo B, Zhang L
Biochemical pharmacology 2021 Oct;192:114741
Biochemical pharmacology 2021 Oct;192:114741
PIKE-A promotes glioblastoma growth by driving PPP flux through increasing G6PD expression mediated by phosphorylation of STAT3.
Sun M, Sheng H, Wu T, Song J, Sun H, Wang Y, Wang J, Li Z, Zhao H, Tan J, Li Y, Chen G, Huang Q, Zhang Y, Lan B, Liu S, Shan C, Zhang S
Biochemical pharmacology 2021 Oct;192:114736
Biochemical pharmacology 2021 Oct;192:114736
Dihydroartemisinin regulates lipid droplet metabolism in hepatic stellate cells by inhibiting lncRNA-H19-induced AMPK signal.
Xia S, Wang Z, Chen L, Zhou Y, Li Y, Wang S, Chen A, Xu X, Shao J, Zhang Z, Tan S, Zhang F, Zheng S
Biochemical pharmacology 2021 Oct;192:114730
Biochemical pharmacology 2021 Oct;192:114730
LncRNA-Malat1 down-regulates miR-211-5p expression to promote neuronal damage from cerebral ischemia reperfusion injury.
Tan X, Guo W, Peng Z, Gu C, Xiang P, Tu Y, Fei H, Liu X, Lu Y, Li M, Wang H, Luo Y, Yang J
Biochemical pharmacology 2021 Oct;192:114694
Biochemical pharmacology 2021 Oct;192:114694
REM Sleep Deprivation Impairs Learning and Memory by Decreasing Brain O-GlcNAc Cycling in Mouse.
Kim SM, Zhang S, Park J, Sung HJ, Tran TT, Chung C, Han IO
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2021 Oct;18(4):2504-2517
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2021 Oct;18(4):2504-2517
Ginsenoside Rg1 prevents bone marrow mesenchymal stem cell senescence via NRF2 and PI3K/Akt signaling.
Wang Z, Wang L, Jiang R, Li C, Chen X, Xiao H, Hou J, Hu L, Huang C, Wang Y
Free radical biology & medicine 2021 Oct;174:182-194
Free radical biology & medicine 2021 Oct;174:182-194
A purified human platelet pellet lysate rich in neurotrophic factors and antioxidants repairs and protects corneal endothelial cells from oxidative stress.
Widyaningrum R, Burnouf T, Nebie O, Delila L, Wang TJ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:112046
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:112046
Panax notoginseng saponins reduces the cisplatin-induced acute renal injury by increasing HIF-1α/BNIP3 to inhibit mitochondrial apoptosis pathway.
Li Q, Zhang Y, Yang Y, Huang S, Zou X, Wei C, Liang T, Zhong X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:111965
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:111965
Deletion of ribosomal paralogs Rpl39 and Rpl39l compromises cell proliferation via protein synthesis and mitochondrial activity.
Zou Q, Qi H
The international journal of biochemistry & cell biology 2021 Oct;139:106070
The international journal of biochemistry & cell biology 2021 Oct;139:106070
Design, synthesis and antitumor evaluation of novel chiral diaryl substituted azetidin-2-one derivatives as tubulin polymerization inhibitors.
Liang Y, Zhang M, Zhou P, Liu M, Li J, Wang Y
Bioorganic chemistry 2021 Oct;115:105239
Bioorganic chemistry 2021 Oct;115:105239
Transcription factor POU4F2 promotes colorectal cancer cell migration and invasion through hedgehog-mediated epithelial-mesenchymal transition.
Guo K, Wang P, Zhang L, Zhou Y, Dai X, Yan Y, Chen Y, Wasan HS, Yu J, Ruan S, Sun L
Cancer science 2021 Oct;112(10):4176-4186
Cancer science 2021 Oct;112(10):4176-4186
ERK1/2 mitogen-activated protein kinase mediates downregulation of intestinal tight junction proteins in heat stress-induced IBD model in pig.
Yong Y, Li J, Gong D, Yu T, Wu L, Hu C, Liu X, Yu Z, Ma X, Gooneratne R, Abd El-Aty AM, Chen J, Ju X
Journal of thermal biology 2021 Oct;101:103103
Journal of thermal biology 2021 Oct;101:103103
Aberrant expression of SNHG12 contributes to N, N-dimethylformamide-induced hepatic apoptosis both in short-term and long-term DMF exposure.
Liu Y, Wen C, Zhang Y, Liu Z, He Q, Cui M, Peng H, Wang Y, Zhang X, Li X, Wang Q
Toxicology research 2021 Oct;10(5):1022-1033
Toxicology research 2021 Oct;10(5):1022-1033
Protocols for Characterization of Cdk5 Kinase Activity.
Terse A, Amin N, Hall B, Bhaskar M, B K B, Utreras E, Pareek TK, Pant H, Kulkarni AB
Current protocols 2021 Oct;1(10):e276
Current protocols 2021 Oct;1(10):e276
CENPA promotes clear cell renal cell carcinoma progression and metastasis via Wnt/β-catenin signaling pathway.
Wang Q, Xu J, Xiong Z, Xu T, Liu J, Liu Y, Chen J, Shi J, Shou Y, Yue C, Liu D, Liang H, Yang H, Yang X, Zhang X
Journal of translational medicine 2021 Oct 9;19(1):417
Journal of translational medicine 2021 Oct 9;19(1):417
sTNFRII-Fc modification protects human UC-MSCs against apoptosis/autophagy induced by TNF-α and enhances their efficacy in alleviating inflammatory arthritis.
Zhao Y, Yang X, Li S, Zhang B, Li S, Wang X, Wang Y, Jia C, Chang Y, Wei W
Stem cell research & therapy 2021 Oct 9;12(1):535
Stem cell research & therapy 2021 Oct 9;12(1):535
Glycogen synthase kinase 3 drives thymocyte egress by suppressing β-catenin activation of Akt.
Liu C, Ma L, Wang Y, Zhao J, Chen P, Chen X, Wang Y, Hu Y, Liu Y, Jia X, Yang Z, Yin X, Wu J, Wu S, Zheng H, Ma X, Sun X, He Y, Lin L, Fu Y, Liao K, Zhou X, Jiang S, Fu G, Tang J, Han W, Chen XL, Fan W, Hong Y, Han J, Huang X, Li BA, Xiao N, Xiao C, Fu G, Liu WH
Science advances 2021 Oct 8;7(41):eabg6262
Science advances 2021 Oct 8;7(41):eabg6262
d-mannose attenuates lipopolysaccharide-induced osteolysis via CPT1A-Mediated lipid metabolic regulation in macrophages.
Zhang Z, Zhou X, Liu J, Zheng Y, Wu Y, Yang W, Yi Y, Liu J, Wang J
Biochemical and biophysical research communications 2021 Oct 8;583:135-141
Biochemical and biophysical research communications 2021 Oct 8;583:135-141
TDAG51 induces renal interstitial fibrosis through modulation of TGF-β receptor 1 in chronic kidney disease.
Carlisle RE, Mohammed-Ali Z, Lu C, Yousof T, Tat V, Nademi S, MacDonald ME, Austin RC, Dickhout JG
Cell death & disease 2021 Oct 8;12(10):921
Cell death & disease 2021 Oct 8;12(10):921
Sulforaphane downregulated fatty acid synthase and inhibited microtubule-mediated mitophagy leading to apoptosis.
Yan Y, Zhou Y, Li J, Zheng Z, Hu Y, Li L, Wu W
Cell death & disease 2021 Oct 7;12(10):917
Cell death & disease 2021 Oct 7;12(10):917
Tetrahedral Framework Nucleic Acid Delivered RNA Therapeutics Significantly Attenuate Pancreatic Cancer Progression via Inhibition of CTR1-Dependent Copper Absorption.
Song G, Dong H, Ma D, Wang H, Ren X, Qu Y, Wu H, Zhu J, Song W, Meng Y, Wang L, Liu T, Shen X, Zhao Y, Zhu C
ACS applied materials & interfaces 2021 Oct 6;13(39):46334-46342
ACS applied materials & interfaces 2021 Oct 6;13(39):46334-46342
Leojaponin inhibits NLRP3 inflammasome activation through restoration of autophagy via upregulating RAPTOR phosphorylation.
Zhang XJ, Shang K, Pu YK, Wang Q, Wang TT, Zou Y, Wang YM, Xu YJ, Li XL, Zhang RH, Xiao WL
Journal of ethnopharmacology 2021 Oct 5;278:114322
Journal of ethnopharmacology 2021 Oct 5;278:114322
p53 transcriptionally regulates SQLE to repress cholesterol synthesis and tumor growth.
Sun H, Li L, Li W, Yang F, Zhang Z, Liu Z, Du W
EMBO reports 2021 Oct 5;22(10):e52537
EMBO reports 2021 Oct 5;22(10):e52537
PFP@PLGA/Cu(12)Sb(4)S(13)-mediated PTT ablates hepatocellular carcinoma by inhibiting the RAS/MAPK/MT-CO1 signaling pathway.
Dong T, Jiang J, Zhang H, Liu H, Zou X, Niu J, Mao Y, Zhu M, Chen X, Li Z, Chen Y, Shi C, Yang X
Nano convergence 2021 Oct 4;8(1):29
Nano convergence 2021 Oct 4;8(1):29
Activation of G protein coupled estrogen receptor prevents chemotherapy-induced intestinal mucositis by inhibiting the DNA damage in crypt cell in an extracellular signal-regulated kinase 1- and 2- dependent manner.
Chen G, Zeng H, Li X, Liu J, Li Z, Xu R, Ma Y, Liu C, Xue B
Cell death & disease 2021 Oct 30;12(11):1034
Cell death & disease 2021 Oct 30;12(11):1034
ATP-binding cassette protein ABCF1 couples transcription and genome surveillance in embryonic stem cells through low-complexity domain.
Choi EB, Vodnala M, Zerbato M, Wang J, Ho JJ, Inouye C, Ding L, Fong YW
Science advances 2021 Oct 29;7(44):eabk2775
Science advances 2021 Oct 29;7(44):eabk2775
Fructus Ligustri Lucidi aqueous extract promotes calcium balance and short-chain fatty acids production in ovariectomized rats.
Chen B, Wei J, Zhu R, Zhang H, Xia B, Liu Y, Dai X, Ye Z, Tian Y, Li R, Zhao D, Mo F, Orekhov AN, Gao S, Brὃmme D, Wang L, Zhang D
Journal of ethnopharmacology 2021 Oct 28;279:114348
Journal of ethnopharmacology 2021 Oct 28;279:114348
Dysfunctional lactate metabolism in human alveolar type II cells from idiopathic pulmonary fibrosis lung explant tissue.
Newton DA, Lottes RG, Ryan RM, Spyropoulos DD, Baatz JE
Respiratory research 2021 Oct 28;22(1):278
Respiratory research 2021 Oct 28;22(1):278
Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation.
Ulferts R, Marcassa E, Timimi L, Lee LC, Daley A, Montaner B, Turner SD, Florey O, Baillie JK, Beale R
Cell reports 2021 Oct 26;37(4):109899
Cell reports 2021 Oct 26;37(4):109899
FABP4 is an independent risk factor for lymph node metastasis and poor prognosis in patients with cervical cancer.
Li G, Wu Q, Gong L, Xu X, Cai J, Xu L, Zeng Y, He X, Wang Z
Cancer cell international 2021 Oct 26;21(1):568
Cancer cell international 2021 Oct 26;21(1):568
The overexpression of Tipe2 in CRC cells suppresses survival while endogenous Tipe2 accelerates AOM/DSS induced-tumor initiation.
Li Y, Zhang N, Ma C, Xu W, Jin G, Zheng Y, Zhang L, Liu B, Gao C, Liu S
Cell death & disease 2021 Oct 26;12(11):1001
Cell death & disease 2021 Oct 26;12(11):1001
Circular RNA circPRKCI contributes to malignant progression of T-cell acute lymphoblastic leukemia by modulating miR-20a-5p/SOX4 axis.
Zheng Y, Niu B, Zhang W, Ru X, Gao Y, Li C, Wu X
Aging 2021 Oct 25;13(20):23757-23768
Aging 2021 Oct 25;13(20):23757-23768
Glaesserella parasuis serotype 4 HPS4-YC disrupts the integrity of the swine tracheal epithelial barrier and facilitates bacterial translocation.
Wang Q, Chang X, Liu M, Lu Q, Zhu M, Lin H, Fan H
Veterinary research 2021 Oct 21;52(1):135
Veterinary research 2021 Oct 21;52(1):135
Layered Double Hydroxide Nanoparticles with Osteogenic Effects as miRNA Carriers to Synergistically Promote Osteogenesis of MSCs.
Yang L, He X, Jing G, Wang H, Niu J, Qian Y, Wang S
ACS applied materials & interfaces 2021 Oct 20;13(41):48386-48402
ACS applied materials & interfaces 2021 Oct 20;13(41):48386-48402
Metformin sensitises hepatocarcinoma cells to methotrexate by targeting dihydrofolate reductase.
Wang Y, Lu H, Sun L, Chen X, Wei H, Suo C, Feng J, Yuan M, Shen S, Jia W, Wang Y, Zhang H, Li Z, Zhong X, Gao P
Cell death & disease 2021 Oct 2;12(10):902
Cell death & disease 2021 Oct 2;12(10):902
ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis.
Karki R, Sundaram B, Sharma BR, Lee S, Malireddi RKS, Nguyen LN, Christgen S, Zheng M, Wang Y, Samir P, Neale G, Vogel P, Kanneganti TD
Cell reports 2021 Oct 19;37(3):109858
Cell reports 2021 Oct 19;37(3):109858
Synapse development is regulated by microglial THIK-1 K(+) channels.
Izquierdo P, Shiina H, Hirunpattarasilp C, Gillis G, Attwell D
Proceedings of the National Academy of Sciences of the United States of America 2021 Oct 19;118(42)
Proceedings of the National Academy of Sciences of the United States of America 2021 Oct 19;118(42)
Targeting CDC7 potentiates ATR-CHK1 signaling inhibition through induction of DNA replication stress in liver cancer.
Guo Y, Wang J, Benedict B, Yang C, van Gemert F, Ma X, Gao D, Wang H, Zhang S, Lieftink C, Beijersbergen RL, Te Riele H, Qiao X, Gao Q, Sun C, Qin W, Bernards R, Wang C
Genome medicine 2021 Oct 18;13(1):166
Genome medicine 2021 Oct 18;13(1):166
Aronia melanocarpa polysaccharide ameliorates inflammation and aging in mice by modulating the AMPK/SIRT1/NF-κB signaling pathway and gut microbiota.
Zhao Y, Liu X, Zheng Y, Liu W, Ding C
Scientific reports 2021 Oct 18;11(1):20558
Scientific reports 2021 Oct 18;11(1):20558
Unexpected Implication of SRP and AGO2 in Parkinson's Disease: Involvement in Alpha-Synuclein Biogenesis.
Hernandez SM, Tikhonova EB, Baca KR, Zhao F, Zhu X, Karamyshev AL
Cells 2021 Oct 18;10(10)
Cells 2021 Oct 18;10(10)
Thromboxane A(2) is involved in the development of hypertension in chronic kidney disease rats.
Hu J, Yang Z, Chen X, Kuang S, Lian Z, Ke G, Liao R, Ma J, Li S, Zhang L, Li Z, Feng Z, Liang H, Lin T, Dong W, Li R, Li Z, Chen Y, Liang X, Shi W, Deng C, Liu S
European journal of pharmacology 2021 Oct 15;909:174435
European journal of pharmacology 2021 Oct 15;909:174435
A systematic approach to decode the mechanism of Cornus in the treatment of hepatocellular carcinoma (HCC).
Shen HY, Li XQ, Fan WQ, Wang YW, Huang F, Wu JQ, Zhang W, Feng XS, Chao X
European journal of pharmacology 2021 Oct 15;909:174405
European journal of pharmacology 2021 Oct 15;909:174405
Antidepressant mechanism of catalpol: Involvement of the PI3K/Akt/Nrf2/HO-1 signaling pathway in rat hippocampus.
Wang J, Chen R, Liu C, Wu X, Zhang Y
European journal of pharmacology 2021 Oct 15;909:174396
European journal of pharmacology 2021 Oct 15;909:174396
Pharmacological activation of SIRT1 by metformin prevented trauma-induced heterotopic ossification through inhibiting macrophage mediated inflammation.
Sun Z, Li J, Luo G, Liu W, He Y, Wang F, Qian Y, Fan C
European journal of pharmacology 2021 Oct 15;909:174386
European journal of pharmacology 2021 Oct 15;909:174386
TRIM46 contributes to high glucose-induced ferroptosis and cell growth inhibition in human retinal capillary endothelial cells by facilitating GPX4 ubiquitination.
Zhang J, Qiu Q, Wang H, Chen C, Luo D
Experimental cell research 2021 Oct 15;407(2):112800
Experimental cell research 2021 Oct 15;407(2):112800
The expression of IFN-β is suppressed by the viral 3D polymerase via its impact on PGAM5 expression during enterovirus D68 infection.
Yang Z, Zheng H, Li H, Chen Y, Hou D, Fan Q, Song J, Guo L, Liu L
Virus research 2021 Oct 15;304:198549
Virus research 2021 Oct 15;304:198549
NLRP3 inflammasome blocked the glycolytic pathway via targeting to PKLR in arsenic-induced hepatic insulin resistance.
Zhang J, Qiu T, Jiang L, Wang N, Zhu Y, Yan R, Wang S, Bai J, Shi X, Yang G, Liu X, Yao X, Sun X
Ecotoxicology and environmental safety 2021 Oct 15;223:112590
Ecotoxicology and environmental safety 2021 Oct 15;223:112590
5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma.
Wang S, Yang H, Su M, Lian F, Cong Z, Wei R, Zhou Y, Li X, Zheng X, Li C, Fu X, Han X, Shi Q, Li C, Zhang N, Geng M, Liu H, Li J, Huang X, Wang J
European journal of medicinal chemistry 2021 Oct 15;222:113592
European journal of medicinal chemistry 2021 Oct 15;222:113592
HBeAg mediates inflammatory functions of macrophages by TLR2 contributing to hepatic fibrosis.
Xie X, Lv H, Liu C, Su X, Yu Z, Song S, Bian H, Tian M, Qin C, Qi J, Zhu Q
BMC medicine 2021 Oct 15;19(1):247
BMC medicine 2021 Oct 15;19(1):247
The Timing and Effects of Low-Dose Ethanol Treatment on Acetaminophen-Induced Liver Injury.
Liu FC, Yu HP, Liao CC, Chou AH, Lee HC
Life (Basel, Switzerland) 2021 Oct 15;11(10)
Life (Basel, Switzerland) 2021 Oct 15;11(10)
Revisiting astrocyte to neuron conversion with lineage tracing in vivo.
Wang LL, Serrano C, Zhong X, Ma S, Zou Y, Zhang CL
Cell 2021 Oct 14;184(21):5465-5481.e16
Cell 2021 Oct 14;184(21):5465-5481.e16
The interaction of S100A16 and GRP78 actives endoplasmic reticulum stress-mediated through the IRE1α/XBP1 pathway in renal tubulointerstitial fibrosis.
Jin R, Zhao A, Han S, Zhang D, Sun H, Li M, Su D, Liang X
Cell death & disease 2021 Oct 13;12(10):942
Cell death & disease 2021 Oct 13;12(10):942
Shift in MSL1 alternative polyadenylation in response to DNA damage protects cancer cells from chemotherapeutic agent-induced apoptosis.
Kunisky AK, Anyaeche VI, Herron RS, Park CY, Hwang HW
Cell reports 2021 Oct 12;37(2):109815
Cell reports 2021 Oct 12;37(2):109815
Vezatin regulates seizures by controlling AMPAR-mediated synaptic activity.
Wang Y, Yuan J, Yu X, Liu X, Tan C, Chen Y, Xu T
Cell death & disease 2021 Oct 12;12(10):936
Cell death & disease 2021 Oct 12;12(10):936
Sitagliptin activates the p62-Keap1-Nrf2 signalling pathway to alleviate oxidative stress and excessive autophagy in severe acute pancreatitis-related acute lung injury.
Kong L, Deng J, Zhou X, Cai B, Zhang B, Chen X, Chen Z, Wang W
Cell death & disease 2021 Oct 11;12(10):928
Cell death & disease 2021 Oct 11;12(10):928
Triiodothyronine ameliorates silica-induced pulmonary inflammation and fibrosis in mice.
Yang M, Wang D, Gan S, Wang B, Yu L, Xie Y, Fan L, Ma J, Chen W
The Science of the total environment 2021 Oct 10;790:148041
The Science of the total environment 2021 Oct 10;790:148041
Effects of Bacillus subtilis on jejunal integrity, redox status, and microbial composition of intrauterine growth restriction suckling piglets.
Yun Y, Ji S, Yu G, Jia P, Niu Y, Zhang H, Zhang X, Wang T, Zhang L
Journal of animal science 2021 Oct 1;99(10)
Journal of animal science 2021 Oct 1;99(10)
Catalpol Weakens Depressive-like Behavior in Mice with Streptozotocin-induced Hyperglycemia via PI3K/AKT/Nrf2/HO-1 Signaling Pathway.
Wu X, Wang J, Song L, Guan Y, Cao C, Cui Y, Zhang Y, Liu C
Neuroscience 2021 Oct 1;473:102-118
Neuroscience 2021 Oct 1;473:102-118
GRIM-19 inhibits proliferation and induces apoptosis in a p53-dependent manner in colorectal cancer cells through the SIRT7/PCAF/MDM2 axis.
Wang D, Wei X, Chen X, Wang Q, Zhang J, Kalvakolanu DV, Guo B, Zhang L
Experimental cell research 2021 Oct 1;407(1):112799
Experimental cell research 2021 Oct 1;407(1):112799
EPS8 supports pancreatic cancer growth by inhibiting BMI1 mediated proteasomal degradation of ALDH7A1.
Tan M, Meng J, Sun X, Fu X, Wang R
Experimental cell research 2021 Oct 1;407(1):112782
Experimental cell research 2021 Oct 1;407(1):112782
Harpagide alleviate neuronal apoptosis and blood-brain barrier leakage by inhibiting TLR4/MyD88/NF-κB signaling pathway in Angiotensin II-induced microglial activation in vitro.
Lu Y, Hao R, Hu Y, Wei Y, Xie Y, Shen Y, Rui Q, Yu G
Chemico-biological interactions 2021 Oct 1;348:109653
Chemico-biological interactions 2021 Oct 1;348:109653
Antagonizing effects of curcumin against mercury-induced autophagic death and trace elements disorder by regulating PI3K/AKT and Nrf2 pathway in the spleen.
Zhao G, Qi L, Wang Y, Li X, Li Q, Tang X, Wang X, Wu C
Ecotoxicology and environmental safety 2021 Oct 1;222:112529
Ecotoxicology and environmental safety 2021 Oct 1;222:112529
Cadmium promotes apoptosis and inflammation via the circ08409/miR-133a/TGFB2 axis in bovine mammary epithelial cells and mouse mammary gland.
Chen Z, Liang Y, Lu Q, Nazar M, Mao Y, Aboragah A, Yang Z, Loor JJ
Ecotoxicology and environmental safety 2021 Oct 1;222:112477
Ecotoxicology and environmental safety 2021 Oct 1;222:112477
Cellular OCIAD2 protein is a proviral factor for hepatitis C virus replication.
Yang Z, Ouyang T, Aoyagi H, Wang T, Xing X, Zhang Y, Wang Y, Li Y, Aizaki H, Li S, Kong L
International journal of biological macromolecules 2021 Oct 1;188:147-159
International journal of biological macromolecules 2021 Oct 1;188:147-159
Switch receptor T3/28 improves long-term persistence and antitumor efficacy of CAR-T cells.
Zhao S, Wang C, Lu P, Lou Y, Liu H, Wang T, Yang S, Bao Z, Han L, Liang X, Ma C, Gao L
Journal for immunotherapy of cancer 2021 Nov;9(12)
Journal for immunotherapy of cancer 2021 Nov;9(12)
Nitrate increases cisplatin chemosensitivity of oral squamous cell carcinoma via REDD1/AKT signaling pathway.
Feng Y, Cao X, Zhao B, Song C, Pang B, Hu L, Zhang C, Wang J, He J, Wang S
Science China. Life sciences 2021 Nov;64(11):1814-1828
Science China. Life sciences 2021 Nov;64(11):1814-1828
Hsa-miR-372-5p regulates the NIMA related kinase 7 and IL-1β release in NK/T-cell lymphoma.
Chen Q, Liu S, Zhang K, Yu B, Zhang W, Zhang H, Chen X
Leukemia & lymphoma 2021 Nov;62(11):2648-2656
Leukemia & lymphoma 2021 Nov;62(11):2648-2656
D-mannose alleviates osteoarthritis progression by inhibiting chondrocyte ferroptosis in a HIF-2α-dependent manner.
Zhou X, Zheng Y, Sun W, Zhang Z, Liu J, Yang W, Yuan W, Yi Y, Wang J, Liu J
Cell proliferation 2021 Nov;54(11):e13134
Cell proliferation 2021 Nov;54(11):e13134
Selenoprotein K deficiency-induced apoptosis: A role for calpain and the ERS pathway.
Jia SZ, Xu XW, Zhang ZH, Chen C, Chen YB, Huang SL, Liu Q, Hoffmann PR, Song GL
Redox biology 2021 Nov;47:102154
Redox biology 2021 Nov;47:102154
Curcumol inhibits the malignant progression of prostate cancer and regulates the PDK1/AKT/mTOR pathway by targeting miR‑9.
Sheng W, Xu W, Ding J, Li L, You X, Wu Y, He Q
Oncology reports 2021 Nov;46(5)
Oncology reports 2021 Nov;46(5)
Protein kinase G signaling pathway is involved in sympathetically maintained pain by modulating ATP-sensitive potassium channels.
Li H, Shang M, Liu L, Lin X, Hu J, Han Q, Xing J
Regional anesthesia and pain medicine 2021 Nov;46(11):1006-1011
Regional anesthesia and pain medicine 2021 Nov;46(11):1006-1011
Interleukin-17 upregulation participates in the pathogenesis of heart failure in mice via NF-κB-dependent suppression of SERCA2a and Cav1.2 expression.
Xue GL, Li DS, Wang ZY, Liu Y, Yang JM, Li CZ, Li XD, Ma JD, Zhang MM, Lu YJ, Li Y, Yang BF, Pan ZW
Acta pharmacologica Sinica 2021 Nov;42(11):1780-1789
Acta pharmacologica Sinica 2021 Nov;42(11):1780-1789
Oxidative stress-mediated apoptosis is involved in bisphenol S-induced reproductive toxicity in male C57BL/6 mice.
Dai W, He QZ, Zhu BQ, Zeng HC
Journal of applied toxicology : JAT 2021 Nov;41(11):1839-1851
Journal of applied toxicology : JAT 2021 Nov;41(11):1839-1851
Propylparaben concentrations in the urine of women and adverse effects on ovarian function in mice in vivo and ovarian cells in vitro.
Jiao L, Li S, Zhai J, Wang D, Li H, Chu W, Geng X, Du Y
Journal of applied toxicology : JAT 2021 Nov;41(11):1719-1731
Journal of applied toxicology : JAT 2021 Nov;41(11):1719-1731
Proteasome inhibition induces macrophage apoptosis via mitochondrial dysfunction.
Wang J, Wang Y, He S, Wang Z, Deng Q, Liang H
Journal of biochemical and molecular toxicology 2021 Nov;35(11):e22894
Journal of biochemical and molecular toxicology 2021 Nov;35(11):e22894
Rutaecarpine alleviates acute pancreatitis in mice and AR42J cells by suppressing the MAPK and NF-κB signaling pathways via calcitonin gene-related peptide.
Huang H, Wang M, Guo Z, Wu D, Wang H, Jia Y, Liu H, Ding J, Peng J
Phytotherapy research : PTR 2021 Nov;35(11):6472-6485
Phytotherapy research : PTR 2021 Nov;35(11):6472-6485
Icariin attenuates renal fibrosis in chronic kidney disease by inhibiting interleukin-1β/transforming growth factor-β-mediated activation of renal fibroblasts.
Wang M, Wang L, Zhou Y, Feng X, Ye C, Wang C
Phytotherapy research : PTR 2021 Nov;35(11):6204-6215
Phytotherapy research : PTR 2021 Nov;35(11):6204-6215
NudCL2 is an autophagy receptor that mediates selective autophagic degradation of CP110 at mother centrioles to promote ciliogenesis.
Liu M, Zhang W, Li M, Feng J, Kuang W, Chen X, Yang F, Sun Q, Xu Z, Hua J, Yang C, Liu W, Shu Q, Yang Y, Zhou T, Xie S
Cell research 2021 Nov;31(11):1199-1211
Cell research 2021 Nov;31(11):1199-1211
A peptide CORO1C-47aa encoded by the circular noncoding RNA circ-0000437 functions as a negative regulator in endometrium tumor angiogenesis.
Li F, Cai Y, Deng S, Yang L, Liu N, Chang X, Jing L, Zhou Y, Li H
The Journal of biological chemistry 2021 Nov;297(5):101182
The Journal of biological chemistry 2021 Nov;297(5):101182
Environmental Pollutant Benzo[a]pyrene Upregulated Long Non-coding RNA HZ07 Inhibits Trophoblast Cell Migration by Inactivating PI3K/AKT/MMP2 Signaling Pathway in Recurrent Pregnancy Loss.
Ye Y, Jiang S, Du T, Ding M, Hou M, Mi C, Liang T, Zhong H, Xie J, Xu W, Zhang H, Zhao X
Reproductive sciences (Thousand Oaks, Calif.) 2021 Nov;28(11):3085-3093
Reproductive sciences (Thousand Oaks, Calif.) 2021 Nov;28(11):3085-3093
miR‑486‑5p suppresses gastric cancer cell growth and migration through downregulation of fibroblast growth factor 9.
Wei W, Liu C, Yao R, Tan Q, Wang Q, Tian H
Molecular medicine reports 2021 Nov;24(5)
Molecular medicine reports 2021 Nov;24(5)
Low-dose exposure to black carbon significantly increase lung injury of cadmium by promoting cellular apoptosis.
Wang L, Bao S, Liu X, Wang F, Zhang J, Dang P, Wang F, Li B, Lin Y
Ecotoxicology and environmental safety 2021 Nov;224:112703
Ecotoxicology and environmental safety 2021 Nov;224:112703
Gas6/Axl signaling pathway promotes proliferation, migration and invasion and inhibits apoptosis in A549 cells.
Wang D, Bi L, Ran J, Zhang L, Xiao N, Li X
Experimental and therapeutic medicine 2021 Nov;22(5):1321
Experimental and therapeutic medicine 2021 Nov;22(5):1321
Metformin attenuates H(2)O(2)-induced osteoblast apoptosis by regulating SIRT3 via the PI3K/AKT pathway.
Yang K, Pei L, Zhou S, Tao L, Zhu Y
Experimental and therapeutic medicine 2021 Nov;22(5):1316
Experimental and therapeutic medicine 2021 Nov;22(5):1316
The anti-neoplastic activities of aloperine in HeLa cervical cancer cells are associated with inhibition of the IL-6-JAK1-STAT3 feedback loop.
Chen YD, Cai FY, Mao YZ, Yang YS, Xu K, Liu XF, Fan WW, Chen W, Jiang FQ, Zhang H
Chinese journal of natural medicines 2021 Nov;19(11):815-824
Chinese journal of natural medicines 2021 Nov;19(11):815-824
Tau phosphorylation and OPA1 proteolysis are unrelated events: Implications for Alzheimer's Disease.
Alavi MV
Biochimica et biophysica acta. Molecular cell research 2021 Nov;1868(12):119116
Biochimica et biophysica acta. Molecular cell research 2021 Nov;1868(12):119116
Chemical Constituents from the Rhizome of Ligusticum chuanxiong Hort. and Their Nrf2 Inducing Activity.
Zhang K, Fang KL, Wang T, Xu LT, Zhao Y, Wang XN, Xiang L, Shen T
Chemistry & biodiversity 2021 Nov;18(11):e2100302
Chemistry & biodiversity 2021 Nov;18(11):e2100302
Chitotriosidase attenuates brain inflammation via HDAC3/NF-κB pathway in D-galactose and aluminum-induced rat model with cognitive impairments.
Yu X, Yu W, Wu L, Yang W, Lü Y
Neuroscience research 2021 Nov;172:73-79
Neuroscience research 2021 Nov;172:73-79
The differentiation state of the Schwann cell progenitor drives phenotypic variation between two contagious cancers.
Owen RS, Ramarathinam SH, Bailey A, Gastaldello A, Hussey K, Skipp PJ, Purcell AW, Siddle HV
PLoS pathogens 2021 Nov;17(11):e1010033
PLoS pathogens 2021 Nov;17(11):e1010033
Perfluorooctane sulfonate induces autophagy-dependent lysosomal membrane permeabilization by weakened interaction between tyrosinated alpha-tubulin and spinster 1.
Dong Z, Qiu T, Zhang J, Sha S, Han X, Kang J, Shi X, Sun X, Jiang L, Yang G, Yao X, Ma Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112540
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112540
Gastrodin promotes hippocampal neurogenesis via PDE9-cGMP-PKG pathway in mice following cerebral ischemia.
Xiao H, Jiang Q, Qiu H, Wu K, Ma X, Yang J, Cheng O
Neurochemistry international 2021 Nov;150:105171
Neurochemistry international 2021 Nov;150:105171
Comparative proteomics reveals Cryptosporidium parvum manipulation of the host cell molecular expression and immune response.
Li T, Liu H, Jiang N, Wang Y, Wang Y, Zhang J, Shen Y, Cao J
PLoS neglected tropical diseases 2021 Nov;15(11):e0009949
PLoS neglected tropical diseases 2021 Nov;15(11):e0009949
Trophoblast-derived interleukin 9 mediates immune cell conversion and contributes to maternal-fetal tolerance.
Sun Y, Wu S, Zhou Q, Li X
Journal of reproductive immunology 2021 Nov;148:103379
Journal of reproductive immunology 2021 Nov;148:103379
Dopamine receptor 2 downregulation and brain-derived neurotrophic factor upregulation in the paraventricular nucleus are correlated with brown adipose tissue thermogenesis in rats with bilateral substantia nigra lesions.
Zhang Y, Zhou L, Lian H, Zhang Y, Tong S, Wang Z
Journal of chemical neuroanatomy 2021 Nov;117:102016
Journal of chemical neuroanatomy 2021 Nov;117:102016
miRNA-223-3p modulates ibrutinib resistance through regulation of the CHUK/Nf-κb signaling pathway in mantle cell lymphoma.
Yuan J, Zhang Q, Wu S, Yan S, Zhao R, Sun Y, Tian X, Zhou K
Experimental hematology 2021 Nov;103:52-59.e2
Experimental hematology 2021 Nov;103:52-59.e2
Isoliquiritigenin alleviates LPS/ D-GalN-induced acute liver failure by activating the PGC-1α/ Nrf2 pathway to reduce oxidative stress and inflammatory response.
Wang L, Wang X, Kong L, Wang S, Huang K, Wu J, Wang C, Sun H, Liu K, Meng Q
International immunopharmacology 2021 Nov;100:108159
International immunopharmacology 2021 Nov;100:108159
Functional role of galectin-9 in directing human innate immune reactions to Gram-negative bacteria and T cell apoptosis.
Schlichtner S, Meyer NH, Yasinska IM, Aliu N, Berger SM, Gibbs BF, Fasler-Kan E, Sumbayev VV
International immunopharmacology 2021 Nov;100:108155
International immunopharmacology 2021 Nov;100:108155
The CCAAT-binding complex mediates azole susceptibility of Aspergillus fumigatus by suppressing SrbA expression and cleavage.
Zhang C, Gao L, Ren Y, Gu H, Zhang Y, Lu L
MicrobiologyOpen 2021 Nov;10(6):e1249
MicrobiologyOpen 2021 Nov;10(6):e1249
Ultrathin 2D Titanium Carbide MXene (Ti(3) C(2) T(x) ) Nanoflakes Activate WNT/HIF-1α-Mediated Metabolism Reprogramming for Periodontal Regeneration.
Cui D, Kong N, Ding L, Guo Y, Yang W, Yan F
Advanced healthcare materials 2021 Nov;10(22):e2101215
Advanced healthcare materials 2021 Nov;10(22):e2101215
DNMT1-induced miR-378a-3p silencing promotes angiogenesis via the NF-κB signaling pathway by targeting TRAF1 in hepatocellular carcinoma.
Zhu B, Chen JJ, Feng Y, Yang JL, Huang H, Chung WY, Hu YL, Xue WJ
Journal of experimental & clinical cancer research : CR 2021 Nov 8;40(1):352
Journal of experimental & clinical cancer research : CR 2021 Nov 8;40(1):352
High throughput sequencing of whole transcriptome and construct of ceRNA regulatory network in RD cells infected with enterovirus D68.
Si J, Tang X, Xu L, Fu H, Li H, He Y, Bao J, Tang J, Li A, Lu N, Yang C
Virology journal 2021 Nov 7;18(1):216
Virology journal 2021 Nov 7;18(1):216
Betaine alleviates right ventricular failure via regulation of Rho A/ROCK signaling pathway in rats with pulmonary arterial hypertension.
Lv Y, Ma P, Wang J, Xu Q, Fan J, Yan L, Ma P, Zhou R
European journal of pharmacology 2021 Nov 5;910:174311
European journal of pharmacology 2021 Nov 5;910:174311
Discovery of a potent MLL1 and WDR5 protein-protein interaction inhibitor with in vivo antitumor activity.
Chen W, Chen X, Li D, Wang X, Long G, Jiang Z, You Q, Guo X
European journal of medicinal chemistry 2021 Nov 5;223:113677
European journal of medicinal chemistry 2021 Nov 5;223:113677
NOX4-derived ROS-induced overexpression of FOXM1 regulates aerobic glycolysis in glioblastoma.
Su X, Yang Y, Yang Q, Pang B, Sun S, Wang Y, Qiao Q, Guo C, Liu H, Pang Q
BMC cancer 2021 Nov 5;21(1):1181
BMC cancer 2021 Nov 5;21(1):1181
Photobiomodulation inhibits the activation of neurotoxic microglia and astrocytes by inhibiting Lcn2/JAK2-STAT3 crosstalk after spinal cord injury in male rats.
Wang X, Li X, Zuo X, Liang Z, Ding T, Li K, Ma Y, Li P, Zhu Z, Ju C, Zhang Z, Song Z, Quan H, Zhang J, Hu X, Wang Z
Journal of neuroinflammation 2021 Nov 5;18(1):256
Journal of neuroinflammation 2021 Nov 5;18(1):256
Ex vivo to in vivo extrapolation of syringic acid and ferulic acid as grape juice proxies for endothelium-dependent vasodilation: Redefining vasoprotective resveratrol of the French paradox.
Huang Y, Xu M, Li J, Chen K, Xia L, Wang W, Ren P, Huang X
Food chemistry 2021 Nov 30;363:130323
Food chemistry 2021 Nov 30;363:130323
WFS1 functions in ER export of vesicular cargo proteins in pancreatic β-cells.
Wang L, Liu H, Zhang X, Song E, Wang Y, Xu T, Li Z
Nature communications 2021 Nov 30;12(1):6996
Nature communications 2021 Nov 30;12(1):6996
Hyaluronic acid hydrogel encapsulated BMP-14-modified ADSCs accelerate cartilage defect repair in rabbits.
Liu H, Rui Y, Liu J, Gao F, Jin Y
Journal of orthopaedic surgery and research 2021 Nov 3;16(1):657
Journal of orthopaedic surgery and research 2021 Nov 3;16(1):657
Taxifolin retards the D-galactose-induced aging process through inhibiting Nrf2-mediated oxidative stress and regulating the gut microbiota in mice.
Liu XL, Zhao YC, Zhu HY, Wu M, Zheng YN, Yang M, Cheng ZQ, Ding CB, Liu WC
Food & function 2021 Nov 29;12(23):12142-12158
Food & function 2021 Nov 29;12(23):12142-12158
Metformin Improves Stemness of Human Adipose-Derived Stem Cells by Downmodulation of Mechanistic Target of Rapamycin (mTOR) and Extracellular Signal-Regulated Kinase (ERK) Signaling.
Chinnapaka S, Yang KS, Flowers Q, Faisal M, Nerone WV, Rubin JP, Ejaz A
Biomedicines 2021 Nov 27;9(12)
Biomedicines 2021 Nov 27;9(12)
Structure-Based Discovery of Potent CARM1 Inhibitors for Solid Tumor and Cancer Immunology Therapy.
Zhang Z, Guo Z, Xu X, Cao D, Yang H, Li Y, Shi Q, Du Z, Guo X, Wang X, Chen D, Zhang Y, Chen L, Zhou K, Li J, Geng M, Huang X, Xiong B
Journal of medicinal chemistry 2021 Nov 25;64(22):16650-16674
Journal of medicinal chemistry 2021 Nov 25;64(22):16650-16674
Proteolysis-Targeting Chimera (PROTAC) Modification of Dovitinib Enhances the Antiproliferative Effect against FLT3-ITD-Positive Acute Myeloid Leukemia Cells.
Cao S, Ma L, Liu Y, Wei M, Yao Y, Li C, Wang R, Liu N, Dong Z, Li X, Li M, Wang X, Yang C, Yang G
Journal of medicinal chemistry 2021 Nov 25;64(22):16497-16511
Journal of medicinal chemistry 2021 Nov 25;64(22):16497-16511
Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion.
Zeng L, Zhou J, Wang X, Zhang Y, Wang M, Su P
Free radical biology & medicine 2021 Nov 20;176:176-188
Free radical biology & medicine 2021 Nov 20;176:176-188
Effect of combination therapy with neural stem cell transplantation and teramethylpyrazine in rats following acute spinal cord injury.
Zhang H, Huang Z, Guo M, Meng L, Piao M, Zhang M, Yu H
Neuroreport 2021 Nov 2;32(16):1311-1319
Neuroreport 2021 Nov 2;32(16):1311-1319
HIF-1-regulated expression of calreticulin promotes breast tumorigenesis and progression through Wnt/β-catenin pathway activation.
Liu X, Xie P, Hao N, Zhang M, Liu Y, Liu P, Semenza GL, He J, Zhang H
Proceedings of the National Academy of Sciences of the United States of America 2021 Nov 2;118(44)
Proceedings of the National Academy of Sciences of the United States of America 2021 Nov 2;118(44)
The Protective Role of Yin-Yang 1 in Cardiac Injury and Remodeling After Myocardial Infarction.
Huang Y, Li L, Chen H, Liao Q, Yang X, Yang D, Xia X, Wang H, Wang WE, Chen L, Zeng C
Journal of the American Heart Association 2021 Nov 2;10(21):e021895
Journal of the American Heart Association 2021 Nov 2;10(21):e021895
Identification of proximal SUMO-dependent interactors using SUMO-ID.
Barroso-Gomila O, Trulsson F, Muratore V, Canosa I, Merino-Cacho L, Cortazar AR, Pérez C, Azkargorta M, Iloro I, Carracedo A, Aransay AM, Elortza F, Mayor U, Vertegaal ACO, Barrio R, Sutherland JD
Nature communications 2021 Nov 18;12(1):6671
Nature communications 2021 Nov 18;12(1):6671
Fluoride Stimulates Anxiety- and Depression-like Behaviors Associated with SIK2-CRTC1 Signaling Dysfunction.
Zhou G, Hu Y, Wang A, Guo M, Du Y, Gong Y, Ding L, Feng Z, Hou X, Xu K, Yu F, Li Z, Ba Y
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13618-13627
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13618-13627
Dendrobium officinale Polysaccharide Alleviates Intestinal Inflammation by Promoting Small Extracellular Vesicle Packaging of miR-433-3p.
Liu H, Liang J, Zhong Y, Xiao G, Efferth T, Georgiev MI, Vargas-De-La-Cruz C, Bajpai VK, Caprioli G, Liu J, Lin J, Wu H, Peng L, Li Y, Ma L, Xiao J, Wang Q
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13510-13523
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13510-13523
Role of Epigallocatechin Gallate in Glucose, Lipid, and Protein Metabolism and L-Theanine in the Metabolism-Regulatory Effects of Epigallocatechin Gallate.
Lin L, Zeng L, Liu A, Yuan D, Peng Y, Zhang S, Li Y, Chen J, Xiao W, Gong Z
Nutrients 2021 Nov 17;13(11)
Nutrients 2021 Nov 17;13(11)
Exopolysaccharides from Bifidobacterium animalis Ameliorate Escherichia coli-Induced IPEC-J2 Cell Damage via Inhibiting Apoptosis and Restoring Autophagy.
Yuan L, Chu B, Chen S, Li Y, Liu N, Zhu Y, Zhou D
Microorganisms 2021 Nov 16;9(11)
Microorganisms 2021 Nov 16;9(11)
Astragalus polysaccharide prevents ferroptosis in a murine model of experimental colitis and human Caco-2 cells via inhibiting NRF2/HO-1 pathway.
Chen Y, Wang J, Li J, Zhu J, Wang R, Xi Q, Wu H, Shi T, Chen W
European journal of pharmacology 2021 Nov 15;911:174518
European journal of pharmacology 2021 Nov 15;911:174518
HMMR is a downstream target of FOXM1 in enhancing proliferation and partial epithelial-to-mesenchymal transition of bladder cancer cells.
Yang D, Ma Y, Zhao P, Ma J, He C
Experimental cell research 2021 Nov 15;408(2):112860
Experimental cell research 2021 Nov 15;408(2):112860
3-Epipachysamine B suppresses proliferation and induces apoptosis of breast cancer cell via PI3K/AKT/mTOR signaling pathway.
Zhang L, Zheng Y, Zeng L, Zhang F, Che D, Cao Z, Huang C, Xian L, Zhang X, Zhang H, Guo Z
Life sciences 2021 Nov 15;285:119995
Life sciences 2021 Nov 15;285:119995
Si-Wu-Tang facilitates ovarian function through improving ovarian microenvironment and angiogenesis in a mouse model of premature ovarian failure.
Zhou F, Song Y, Liu X, Zhang C, Li F, Hu R, Huang Y, Ma W, Song K, Zhang M
Journal of ethnopharmacology 2021 Nov 15;280:114431
Journal of ethnopharmacology 2021 Nov 15;280:114431
Protective effect of the effective part of Andrographis paniculata (Burm.f.) Nees on PM(2.5)-induced lung injury in rats by modulating the NF-κB pathway.
Yao H, Zhao J, Zhu L, Xie Y, Zhao N, Yao R, Sun H, Han G
Journal of ethnopharmacology 2021 Nov 15;280:114420
Journal of ethnopharmacology 2021 Nov 15;280:114420
Yi-Qi-Jian-Pi formula modulates the PI3K/AKT signaling pathway to attenuate acute-on-chronic liver failure by suppressing hypoxic injury and apoptosis in vivo and in vitro.
Tang L, Wang F, Xiao L, Shen M, Xia S, Zhang Z, Zhang F, Zheng S, Tan S
Journal of ethnopharmacology 2021 Nov 15;280:114411
Journal of ethnopharmacology 2021 Nov 15;280:114411
Cutting Edge: Caspase-8 Is a Linchpin in Caspase-3 and Gasdermin D Activation to Control Cell Death, Cytokine Release, and Host Defense during Influenza A Virus Infection.
Wang Y, Karki R, Zheng M, Kancharana B, Lee S, Kesavardhana S, Hansen BS, Pruett-Miller SM, Kanneganti TD
Journal of immunology (Baltimore, Md. : 1950) 2021 Nov 15;207(10):2411-2416
Journal of immunology (Baltimore, Md. : 1950) 2021 Nov 15;207(10):2411-2416
SARS-CoV-2 inhibits induction of the MHC class I pathway by targeting the STAT1-IRF1-NLRC5 axis.
Yoo JS, Sasaki M, Cho SX, Kasuga Y, Zhu B, Ouda R, Orba Y, de Figueiredo P, Sawa H, Kobayashi KS
Nature communications 2021 Nov 15;12(1):6602
Nature communications 2021 Nov 15;12(1):6602
Heat stress induces oxidative stress and activates the KEAP1-NFE2L2-ARE pathway in bovine endometrial epithelial cells†.
Murata H, Kunii H, Kusama K, Sakurai T, Bai H, Kawahara M, Takahashi M
Biology of reproduction 2021 Nov 15;105(5):1114-1125
Biology of reproduction 2021 Nov 15;105(5):1114-1125
Xbp1s-Ddit3 promotes MCT-induced pulmonary hypertension.
Jiang H, Ding D, He Y, Li X, Xu Y, Liu X
Clinical science (London, England : 1979) 2021 Nov 12;135(21):2467-2481
Clinical science (London, England : 1979) 2021 Nov 12;135(21):2467-2481
The Mutational Landscape of PTK7 in Congenital Scoliosis and Adolescent Idiopathic Scoliosis.
Su Z, Yang Y, Wang S, Zhao S, Zhao H, Li X, Niu Y, Deciphering Disorders Involving Scoliosis And COmorbidities Disco Study Group, Qiu G, Wu Z, Wu N, Zhang TJ
Genes 2021 Nov 12;12(11)
Genes 2021 Nov 12;12(11)
Phase separation drives RNA virus-induced activation of the NLRP6 inflammasome.
Shen C, Li R, Negro R, Cheng J, Vora SM, Fu TM, Wang A, He K, Andreeva L, Gao P, Tian Z, Flavell RA, Zhu S, Wu H
Cell 2021 Nov 11;184(23):5759-5774.e20
Cell 2021 Nov 11;184(23):5759-5774.e20
Erythritol Improves Nonalcoholic Fatty Liver Disease by Activating Nrf2 Antioxidant Capacity.
Jin M, Wei Y, Yu H, Ma X, Yan S, Zhao L, Ding L, Cheng J, Feng H
Journal of agricultural and food chemistry 2021 Nov 10;69(44):13080-13092
Journal of agricultural and food chemistry 2021 Nov 10;69(44):13080-13092
AICAR enhances the cytotoxicity of PFKFB3 inhibitor in an AMPK signaling-independent manner in colorectal cancer cells.
Yan S, Yuan D, Li Q, Li S, Zhang F
Medical oncology (Northwood, London, England) 2021 Nov 10;39(1):10
Medical oncology (Northwood, London, England) 2021 Nov 10;39(1):10
Isorhapontigenin (ISO) inhibits EMT through FOXO3A/METTL14/VIMENTIN pathway in bladder cancer cells.
Zhang N, Hua X, Tu H, Li J, Zhang Z, Max C
Cancer letters 2021 Nov 1;520:400-408
Cancer letters 2021 Nov 1;520:400-408
SAA1 is transcriptionally activated by STAT3 and accelerates renal interstitial fibrosis by inducing endoplasmic reticulum stress.
Zhang F, Zhou X, Zou H, Liu L, Li X, Ruan Y, Xie Y, Shi M, Xiao Y, Wang Y, Zhou Y, Wu Y, Guo B
Experimental cell research 2021 Nov 1;408(1):112856
Experimental cell research 2021 Nov 1;408(1):112856
Competing endogenous RNA network associated with oxygen-induced retinopathy: Expression of the network and identification of the MALAT1/miR-124-3p/EGR1 regulatory axis.
Xia F, Xu Y, Zhang X, Lyu J, Zhao P
Experimental cell research 2021 Nov 1;408(1):112783
Experimental cell research 2021 Nov 1;408(1):112783
A naturally occurring FXR agonist, alisol B 23-acetate, protects against renal ischemia-reperfusion injury.
Luan ZL, Ming WH, Sun XW, Zhang C, Zhou Y, Zheng F, Yang YL, Guan YF, Zhang XY
American journal of physiology. Renal physiology 2021 Nov 1;321(5):F617-F628
American journal of physiology. Renal physiology 2021 Nov 1;321(5):F617-F628
Vps13D functions in a Pink1-dependent and Parkin-independent mitophagy pathway.
Shen JL, Fortier TM, Wang R, Baehrecke EH
The Journal of cell biology 2021 Nov 1;220(11)
The Journal of cell biology 2021 Nov 1;220(11)
LncRNA NEAT1 mediates intestinal inflammation by regulating TNFRSF1B.
Pan S, Liu R, Wu X, Ma K, Luo W, Nie K, Zhang C, Meng X, Tong T, Chen X, Wang X, Deng M
Annals of translational medicine 2021 May;9(9):773
Annals of translational medicine 2021 May;9(9):773
Deleterious impact of nerve growth factor precursor (proNGF) on bladder urothelial and smooth muscle cells.
Mossa AH, Abdaem J, Cammisotto P, Campeau L
Cellular signalling 2021 May;81:109936
Cellular signalling 2021 May;81:109936
Efficient Killing of Multidrug-Resistant Internalized Bacteria by AIEgens In Vivo.
Li Y, Liu F, Zhang J, Liu X, Xiao P, Bai H, Chen S, Wang D, Sung SHP, Kwok RTK, Shen J, Zhu K, Tang BZ
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 May;8(9):2001750
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 May;8(9):2001750
Amelioration of Murine Macrophage Activation Syndrome by Monomethyl Fumarate in Both a Heme Oxygenase 1-Dependent and Heme Oxygenase 1-Independent Manner.
Biswas C, Chu N, Burn TN, Kreiger PA, Behrens EM
Arthritis & rheumatology (Hoboken, N.J.) 2021 May;73(5):885-895
Arthritis & rheumatology (Hoboken, N.J.) 2021 May;73(5):885-895
Elevated type I interferon responses potentiate metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice.
Lei Y, Guerra Martinez C, Torres-Odio S, Bell SL, Birdwell CE, Bryant JD, Tong CW, Watson RO, West LC, West AP
Science advances 2021 May;7(22)
Science advances 2021 May;7(22)
Novel Japanese encephalitis virus NS1-based vaccine: Truncated NS1 fused with E. coli heat labile enterotoxin B subunit.
Wan J, Wang T, Xu J, Ouyang T, Wang Q, Zhang Y, Weng S, Li Y, Wang Y, Xin X, Wang X, Li S, Kong L
EBioMedicine 2021 May;67:103353
EBioMedicine 2021 May;67:103353
Cu-induced mitochondrial dysfunction is mediated by abnormal mitochondrial fission through oxidative stress in primary chicken embryo hepatocytes.
Wu L, Kang Z, Qiao N, Wang C, Tang Z
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2021 May;65:126721
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2021 May;65:126721
Changes of lipid profiles in human umbilical vein endothelial cells exposed to zirconia nanoparticles with or without the presence of free fatty acids.
Cheng X, Guo H, Xian Y, Xie X
Journal of applied toxicology : JAT 2021 May;41(5):765-774
Journal of applied toxicology : JAT 2021 May;41(5):765-774
Comparison of toxicity of Ti(3) C(2) and Nb(2) C Mxene quantum dots (QDs) to human umbilical vein endothelial cells.
Gu M, Dai Z, Yan X, Ma J, Niu Y, Lan W, Wang X, Xu Q
Journal of applied toxicology : JAT 2021 May;41(5):745-754
Journal of applied toxicology : JAT 2021 May;41(5):745-754
Long non-coding RNA LEISA promotes progression of lung adenocarcinoma via enhancing interaction between STAT3 and IL-6 promoter.
Wu S, Liu B, Zhang Y, Hong R, Liu S, Xiang T, Tao T, Cai J, Wu J, Li M, Guan H
Oncogene 2021 May;40(19):3449-3459
Oncogene 2021 May;40(19):3449-3459
miR-509-3p Suppresses Migration, Invasion, and Epithelial- Mesenchymal Transition in Melanoma Cells by Targeting Collagen Triple Helix Repeat Containing 1.
Yuan K, Sun Y, Ji Y
Balkan medical journal 2021 May;38(3):177-182
Balkan medical journal 2021 May;38(3):177-182
Cross-talk Between Histone and DNA Methylation Mediates Bone Loss in Hind Limb Unloading.
Li B, Zhao J, Ma J, Chen W, Zhou C, Wei W, Li S, Li G, Xin G, Zhang Y, Liu J, Wang Y, Ma X
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2021 May;36(5):956-967
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2021 May;36(5):956-967
Long noncoding RNA DUXAP10 promotes the stemness of glioma cells by recruiting HuR to enhance Sox12 mRNA stability.
Wu B, Yang C, Fang Y, Ding W, Zhang Y
Environmental toxicology 2021 May;36(5):840-849
Environmental toxicology 2021 May;36(5):840-849
Glucose-dependent insulinotropic polypeptide modifies adipose plasticity and promotes beige adipogenesis of human omental adipose-derived stem cells.
Chen X, He X, Guo Y, Liu L, Li H, Tan J, Feng W, Guan H, Cao X, Xiao H, Li Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21534
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21534
Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer's disease.
Bao WD, Pang P, Zhou XT, Hu F, Xiong W, Chen K, Wang J, Wang F, Xie D, Hu YZ, Han ZT, Zhang HH, Wang WX, Nelson PT, Chen JG, Lu Y, Man HY, Liu D, Zhu LQ
Cell death and differentiation 2021 May;28(5):1548-1562
Cell death and differentiation 2021 May;28(5):1548-1562
Cholesterol 25-hydroxylase inhibits Senecavirus A replication by enzyme activity-dependent and independent mechanisms.
Zhu H, Yan J, Liu X, Li L, Liu W, Wang X, Jiang P, Bai J
Veterinary microbiology 2021 May;256:109038
Veterinary microbiology 2021 May;256:109038
IL-1/IL-1R signaling induced by all-trans-retinal contributes to complement alternative pathway activation in retinal pigment epithelium.
Cheng X, He D, Liao C, Lin S, Tang L, Wang YL, Hu J, Li W, Liu Z, Wu Y, Liao Y
Journal of cellular physiology 2021 May;236(5):3660-3674
Journal of cellular physiology 2021 May;236(5):3660-3674
Free Deoxycholic Acid Exacerbates Vascular Calcification in CKD through ER Stress-Mediated ATF4 Activation.
Miyazaki-Anzai S, Masuda M, Shiozaki Y, Keenan AL, Chonchol M, Kremoser C, Miyazaki M
Kidney360 2021 May;2(5):857-868
Kidney360 2021 May;2(5):857-868
Long non-coding RNA PCA3 inhibits lipid accumulation and atherosclerosis through the miR-140-5p/RFX7/ABCA1 axis.
Zhao ZW, Zhang M, Liao LX, Zou J, Wang G, Wan XJ, Zhou L, Li H, Qin YS, Yu XH, Tang CK
Biochimica et biophysica acta. Molecular and cell biology of lipids 2021 May;1866(5):158904
Biochimica et biophysica acta. Molecular and cell biology of lipids 2021 May;1866(5):158904
Anti-osteoporotic effects of alisol C 23-acetate via osteoclastogenesis inhibition.
Jia X, Zhu H, Li G, Lan M, Li X, Huang M, Xu W, Wu S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 May;137:111321
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 May;137:111321
Reversine suppresses osteosarcoma cell growth through targeting BMP-Smad1/5/8-mediated angiogenesis.
Hu L, Li K, Lin L, Qian F, Li P, Zhu L, Cai H, You L, Song J, Kok SHL, Lee KKH, Yang X, Cheng X
Microvascular research 2021 May;135:104136
Microvascular research 2021 May;135:104136
Inhibition of NLRP3 inflammasome ameliorates podocyte damage by suppressing lipid accumulation in diabetic nephropathy.
Wu M, Yang Z, Zhang C, Shi Y, Han W, Song S, Mu L, Du C, Shi Y
Metabolism: clinical and experimental 2021 May;118:154748
Metabolism: clinical and experimental 2021 May;118:154748
SREBP1/FASN/cholesterol axis facilitates radioresistance in colorectal cancer.
Jin Y, Chen Z, Dong J, Wang B, Fan S, Yang X, Cui M
FEBS open bio 2021 May;11(5):1343-1352
FEBS open bio 2021 May;11(5):1343-1352
Multi-omics approaches identify SF3B3 and SIRT3 as candidate autophagic regulators and druggable targets in invasive breast carcinoma.
Zhang S, Zhang J, An Y, Zeng X, Qin Z, Zhao Y, Xu H, Liu B
Acta pharmaceutica Sinica. B 2021 May;11(5):1227-1245
Acta pharmaceutica Sinica. B 2021 May;11(5):1227-1245
The role of PKA/PP2B-mediated Drp1 phosphorylation and the subsequent EGFR inhibition in Cr(VI)-induced premature senescence.
Li S, Ma Y, Liang Y, Liang N, Ye S, Xiao F
Ecotoxicology and environmental safety 2021 May 7;218:112300
Ecotoxicology and environmental safety 2021 May 7;218:112300
De novo purine biosynthesis is a major driver of chemoresistance in glioblastoma.
Shireman JM, Atashi F, Lee G, Ali ES, Saathoff MR, Park CH, Savchuk S, Baisiwala S, Miska J, Lesniak MS, James CD, Stupp R, Kumthekar P, Horbinski CM, Ben-Sahra I, Ahmed AU
Brain : a journal of neurology 2021 May 7;144(4):1230-1246
Brain : a journal of neurology 2021 May 7;144(4):1230-1246
Oxidative stress induced by NOX2 contributes to neuropathic pain via plasma membrane translocation of PKCε in rat dorsal root ganglion neurons.
Xu J, Wu S, Wang J, Wang J, Yan Y, Zhu M, Zhang D, Jiang C, Liu T
Journal of neuroinflammation 2021 May 6;18(1):106
Journal of neuroinflammation 2021 May 6;18(1):106
Redd1 knockdown prevents doxorubicin-induced cardiac senescence.
Huang P, Bai L, Liu L, Fu J, Wu K, Liu H, Liu Y, Qi B, Qi B
Aging 2021 May 6;13(10):13788-13806
Aging 2021 May 6;13(10):13788-13806
Circular RNA Calm4 Regulates Hypoxia-Induced Pulmonary Arterial Smooth Muscle Cells Pyroptosis via the Circ-Calm4/miR-124-3p/PDCD6 Axis.
Jiang Y, Liu H, Yu H, Zhou Y, Zhang J, Xin W, Li Y, He S, Ma C, Zheng X, Zhang L, Zhao X, Wu B, Jiang C, Zhu D
Arteriosclerosis, thrombosis, and vascular biology 2021 May 5;41(5):1675-1693
Arteriosclerosis, thrombosis, and vascular biology 2021 May 5;41(5):1675-1693
Evaluation of Stable LifeAct-mRuby2- and LAMP1-NeonGreen Expressing A549 Cell Lines for Investigation of Aspergillus fumigatus Interaction with Pulmonary Cells.
Schiefermeier-Mach N, Moresco V, Geley S, Heinrich L, Lechner L, Oberhauser H, Perkhofer S
International journal of molecular sciences 2021 May 31;22(11)
International journal of molecular sciences 2021 May 31;22(11)
High-fat diet impairs ferroptosis and promotes cancer invasiveness via downregulating tumor suppressor ACSL4 in lung adenocarcinoma.
Zhang Y, Li S, Li F, Lv C, Yang QK
Biology direct 2021 May 31;16(1):10
Biology direct 2021 May 31;16(1):10
FKBP52 overexpression accelerates hippocampal-dependent memory impairments in a tau transgenic mouse model.
Criado-Marrero M, Gebru NT, Gould LA, Blazier DM, Vidal-Aguiar Y, Smith TM, Abdelmaboud SS, Shelton LB, Wang X, Dahrendorff J, Beaulieu-Abdelahad D, Dickey CA, Blair LJ
NPJ aging and mechanisms of disease 2021 May 3;7(1):9
NPJ aging and mechanisms of disease 2021 May 3;7(1):9
Ribonucleic Acid Export 1 Is a Kinetochore-Associated Protein That Participates in Chromosome Alignment in Mouse Oocytes.
Chen F, Jiao XF, Meng F, Wang YS, Ding ZM, Miao YL, Xiong JJ, Huo LJ
International journal of molecular sciences 2021 May 3;22(9)
International journal of molecular sciences 2021 May 3;22(9)
Effect of circular RNA, mmu_circ_0000296, on neuronal apoptosis in chronic cerebral ischaemia via the miR-194-5p/Runx3/Sirt1 axis.
Huang K, Yang C, Zheng J, Liu X, Liu J, Che D, Xue Y, An P, Wang D, Ruan X, Yu B
Cell death discovery 2021 May 29;7(1):124
Cell death discovery 2021 May 29;7(1):124
Oocyte-secreted factors strongly stimulate sFRP4 expression in human cumulus cells.
Esfandyari S, Winston NJ, Fierro MA, Scoccia H, Stocco C
Molecular human reproduction 2021 May 29;27(6)
Molecular human reproduction 2021 May 29;27(6)
Vertebrate cells differentially interpret ciliary and extraciliary cAMP.
Truong ME, Bilekova S, Choksi SP, Li W, Bugaj LJ, Xu K, Reiter JF
Cell 2021 May 27;184(11):2911-2926.e18
Cell 2021 May 27;184(11):2911-2926.e18
Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells.
Le Vasseur M, Friedman J, Jost M, Xu J, Yamada J, Kampmann M, Horlbeck MA, Salemi MR, Phinney BS, Weissman JS, Nunnari J
eLife 2021 May 26;10
eLife 2021 May 26;10
Evaluation of the nephrotoxicity and safety of low-dose aristolochic acid, extending to the use of Xixin (Asurum), by determination of methylglyoxal and d-lactate.
Lin CE, Lin PY, Yang WC, Huang YS, Lin TY, Chen CM, Chen HS, Lee JA, Chen SM
Journal of ethnopharmacology 2021 May 23;272:113945
Journal of ethnopharmacology 2021 May 23;272:113945
Downregulation of CD151 restricts VCAM-1 mediated leukocyte infiltration to reduce neurobiological injuries after experimental stroke.
Gao C, Jia W, Xu W, Wu Q, Wu J
Journal of neuroinflammation 2021 May 22;18(1):118
Journal of neuroinflammation 2021 May 22;18(1):118
Maternal folic acid supplementation prevents autistic behaviors in a rat model induced by prenatal exposure to valproic acid.
Di Y, Li Z, Li J, Cheng Q, Zheng Q, Zhai C, Kang M, Wei C, Lan J, Fan J, Ren W, Tian Y
Food & function 2021 May 21;12(10):4544-4555
Food & function 2021 May 21;12(10):4544-4555
Ganoderma lucidum stimulates autophagy-dependent longevity pathways in Caenorhabditis elegans and human cells.
Peng HH, Wu CY, Hsiao YC, Martel J, Ke PY, Chiu CY, Liau JC, Chang IT, Su YH, Ko YF, Young JD, Ojcius DM
Aging 2021 May 20;13(10):13474-13495
Aging 2021 May 20;13(10):13474-13495
USP18 positively regulates innate antiviral immunity by promoting K63-linked polyubiquitination of MAVS.
Hou J, Han L, Zhao Z, Liu H, Zhang L, Ma C, Yi F, Liu B, Zheng Y, Gao C
Nature communications 2021 May 20;12(1):2970
Nature communications 2021 May 20;12(1):2970
The miR-378c-Samd1 circuit promotes phenotypic modulation of vascular smooth muscle cells and foam cells formation in atherosclerosis lesions.
Tian S, Cao Y, Wang J, Bi Y, Zhong J, Meng X, Sun W, Yang R, Gan L, Wang X, Li H, Wang R
Scientific reports 2021 May 18;11(1):10548
Scientific reports 2021 May 18;11(1):10548
Mir-139-5p inhibits glioma cell proliferation and progression by targeting GABRA1.
Wang L, Liu Y, Yu Z, Gong J, Deng Z, Ren N, Zhong Z, Cai H, Tang Z, Cheng H, Chen S, He Z
Journal of translational medicine 2021 May 17;19(1):213
Journal of translational medicine 2021 May 17;19(1):213
LncRNA ZNF674-AS1 regulates granulosa cell glycolysis and proliferation by interacting with ALDOA.
Li D, Wang X, Li G, Dang Y, Zhao S, Qin Y
Cell death discovery 2021 May 16;7(1):107
Cell death discovery 2021 May 16;7(1):107
Exercise improves lipid droplet metabolism disorder through activation of AMPK-mediated lipophagy in NAFLD.
Li H, Dun Y, Zhang W, You B, Liu Y, Fu S, Qiu L, Cheng J, Ripley-Gonzalez JW, Liu S
Life sciences 2021 May 15;273:119314
Life sciences 2021 May 15;273:119314
SET8 mitigates hepatic ischemia/reperfusion injury in mice by suppressing MARK4/NLRP3 inflammasome pathway.
Luo Y, Huang Z, Mou T, Pu J, Li T, Li Z, Yang H, Yan P, Wu Z, Wu Q
Life sciences 2021 May 15;273:119286
Life sciences 2021 May 15;273:119286
Purification, structural characterization, and PCSK9 secretion inhibitory effect of the novel alkali-extracted polysaccharide from Cordyceps militaris.
Wang J, Wang Y, Yang X, Lin P, Liu N, Li X, Zhang B, Guo S
International journal of biological macromolecules 2021 May 15;179:407-417
International journal of biological macromolecules 2021 May 15;179:407-417
Asenapine maleate inhibits angiotensin II-induced proliferation and activation of cardiac fibroblasts via the ROS/TGFβ1/MAPK signaling pathway.
Wu HH, Meng TT, Chen JM, Meng FL, Wang SY, Liu RH, Chen JN, Ning B, Li Y, Su GH
Biochemical and biophysical research communications 2021 May 14;553:172-179
Biochemical and biophysical research communications 2021 May 14;553:172-179
Hyperactivation of HER2-SHCBP1-PLK1 axis promotes tumor cell mitosis and impairs trastuzumab sensitivity to gastric cancer.
Shi W, Zhang G, Ma Z, Li L, Liu M, Qin L, Yu Z, Zhao L, Liu Y, Zhang X, Qin J, Ye H, Jiang X, Zhou H, Sun H, Jiao Z
Nature communications 2021 May 14;12(1):2812
Nature communications 2021 May 14;12(1):2812
trans-Fatty acids promote p53-dependent apoptosis triggered by cisplatin-induced DNA interstrand crosslinks via the Nox-RIP1-ASK1-MAPK pathway.
Hirata Y, Takahashi M, Yamada Y, Matsui R, Inoue A, Ashida R, Noguchi T, Matsuzawa A
Scientific reports 2021 May 14;11(1):10350
Scientific reports 2021 May 14;11(1):10350
A subcellular map of the human kinome.
Zhang H, Cao X, Tang M, Zhong G, Si Y, Li H, Zhu F, Liao Q, Li L, Zhao J, Feng J, Li S, Wang C, Kaulich M, Wang F, Chen L, Li L, Xia Z, Liang T, Lu H, Feng XH, Zhao B
eLife 2021 May 14;10
eLife 2021 May 14;10
Berberine-photodynamic therapy sensitizes melanoma cells to cisplatin-induced apoptosis through ROS-mediated P38 MAPK pathways.
Wang X, Gong Q, Song C, Fang J, Yang Y, Liang X, Huang X, Liu J
Toxicology and applied pharmacology 2021 May 1;418:115484
Toxicology and applied pharmacology 2021 May 1;418:115484
High fat suppresses SOD1 activity by reducing copper chaperone for SOD1 associated with neurodegeneration and memory decline.
Lu P, Yan HJ, Yang C, Feng WC, Hu F, Wu YY, Sun WW, Gao MM, Long YS
Life sciences 2021 May 1;272:119243
Life sciences 2021 May 1;272:119243
Short-term but not long-term high fat diet feeding protects against pressure overload-induced heart failure through activation of mitophagy.
Tan Y, Li M, Wu G, Lou J, Feng M, Xu J, Zhou J, Zhang P, Yang H, Dong L, Li J, Zhang X, Gao F
Life sciences 2021 May 1;272:119242
Life sciences 2021 May 1;272:119242
6-Gingerol attenuates ventilator-induced lung injury via anti-inflammation and antioxidative stress by modulating the PPARγ/NF-κBsignalling pathway in rats.
Hong W, Zhi FX, Kun TH, Hua FJ, Huan Ling L, Fang F, Wen C, Jie W, Yang LC
International immunopharmacology 2021 Mar;92:107367
International immunopharmacology 2021 Mar;92:107367
Total glycosides from stems of Cistanche tubulosa alleviate depression-like behaviors: bidirectional interaction of the phytochemicals and gut microbiota.
Fan L, Peng Y, Wang J, Ma P, Zhao L, Li X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Mar;83:153471
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Mar;83:153471
Androgen Receptor Stimulates Hexokinase 2 and Induces Glycolysis by PKA/CREB Signaling in Hepatocellular Carcinoma.
Sun RF, Zhao CY, Chen S, Yu W, Zhou MM, Gao CR
Digestive diseases and sciences 2021 Mar;66(3):802-813
Digestive diseases and sciences 2021 Mar;66(3):802-813
Circadian clock genes promote glioma progression by affecting tumour immune infiltration and tumour cell proliferation.
Wang Z, Su G, Dai Z, Meng M, Zhang H, Fan F, Liu Z, Zhang L, Weygant N, He F, Fang N, Zhang L, Cheng Q
Cell proliferation 2021 Mar;54(3):e12988
Cell proliferation 2021 Mar;54(3):e12988
Nbs1-mediated DNA damage repair pathway regulates haematopoietic stem cell development and embryonic haematopoiesis.
Chen Y, Sun J, Ju Z, Wang ZQ, Li T
Cell proliferation 2021 Mar;54(3):e12972
Cell proliferation 2021 Mar;54(3):e12972
MiR-520a-3p inhibits malignant progression of epithelial ovarian cancer by targeting SUV39H1 expression.
Li J, Shao W, Zhao J
Human cell 2021 Mar;34(2):570-578
Human cell 2021 Mar;34(2):570-578
Oncogenic AURKA-enhanced N(6)-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells.
Peng F, Xu J, Cui B, Liang Q, Zeng S, He B, Zou H, Li M, Zhao H, Meng Y, Chen J, Liu B, Lv S, Chu P, An F, Wang Z, Huang J, Zhan Y, Liao Y, Lu J, Xu L, Zhang J, Sun Z, Li Z, Wang F, Lam EW, Liu Q
Cell research 2021 Mar;31(3):345-361
Cell research 2021 Mar;31(3):345-361
Chondrocyte ferroptosis contribute to the progression of osteoarthritis.
Yao X, Sun K, Yu S, Luo J, Guo J, Lin J, Wang G, Guo Z, Ye Y, Guo F
Journal of orthopaedic translation 2021 Mar;27:33-43
Journal of orthopaedic translation 2021 Mar;27:33-43
miR-130b-3p regulates M1 macrophage polarization via targeting IRF1.
Guo Q, Zhu X, Wei R, Zhao L, Zhang Z, Yin X, Zhang Y, Chu C, Wang B, Li X
Journal of cellular physiology 2021 Mar;236(3):2008-2022
Journal of cellular physiology 2021 Mar;236(3):2008-2022
Apoptosis inhibition is involved in improvement of sevoflurane-induced cognitive impairment following normobaric hyperoxia preconditioning in aged rats.
Wang Y, Yin CP, Tai YL, Zhao ZJ, Hou ZY, Wang QJ
Experimental and therapeutic medicine 2021 Mar;21(3):203
Experimental and therapeutic medicine 2021 Mar;21(3):203
Regulation of ARL2 in colorectal cancer cell proliferation and tumorigenicity, and its negative association with AXL.
Pang X, Wang Y, Miao B, Fei S, Chen W
Oncology letters 2021 Mar;21(3):196
Oncology letters 2021 Mar;21(3):196
Three phytosterols from sweet potato inhibit MCF7-xenograft-tumor growth through modulating gut microbiota homeostasis and SCFAs secretion.
Han B, Jiang P, Jiang L, Li X, Ye X
Food research international (Ottawa, Ont.) 2021 Mar;141:110147
Food research international (Ottawa, Ont.) 2021 Mar;141:110147
d-Mannose suppresses osteoarthritis development in vivo and delays IL-1β-induced degeneration in vitro by enhancing autophagy activated via the AMPK pathway.
Lin Z, Miao J, Zhang T, He M, Zhou X, Zhang H, Gao Y, Bai L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Mar;135:111199
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Mar;135:111199
Gasdermin D Protects Mouse Podocytes Against High-Glucose-Induced Inflammation and Apoptosis via the C-Jun N-Terminal Kinase (JNK) Pathway.
Li H, Zhao K, Li Y
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 9;27:e928411
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 9;27:e928411
Plumbagin, a Biomolecule with (Anti)Osteoclastic Properties.
Sultanli S, Ghumnani S, Ashma R, Kubatzky KF
International journal of molecular sciences 2021 Mar 9;22(5)
International journal of molecular sciences 2021 Mar 9;22(5)
Expression of Talin-1 in endometriosis and its possible role in pathogenesis.
Tang X, Li Q, Li L, Jiang J
Reproductive biology and endocrinology : RB&E 2021 Mar 9;19(1):42
Reproductive biology and endocrinology : RB&E 2021 Mar 9;19(1):42
lncRNA GCAT1 is involved in premature ovarian insufficiency by regulating p27 translation in GCs via competitive binding to PTBP1.
Li D, Wang X, Dang Y, Zhang X, Zhao S, Lu G, Chan WY, Leung PCK, Qin Y
Molecular therapy. Nucleic acids 2021 Mar 5;23:132-141
Molecular therapy. Nucleic acids 2021 Mar 5;23:132-141
Combining combretastatin A4 phosphate with ginsenoside Rd synergistically inhibited hepatocellular carcinoma by reducing HIF-1α via PI3K/AKT/mTOR signalling pathway.
Yang X, Gao M, Miao M, Jiang C, Zhang D, Yin Z, Ni Y, Chen J, Zhang J
The Journal of pharmacy and pharmacology 2021 Mar 4;73(2):263-271
The Journal of pharmacy and pharmacology 2021 Mar 4;73(2):263-271
PUMA facilitates EMI1-promoted cytoplasmic Rad51 ubiquitination and inhibits DNA repair in stem and progenitor cells.
Kang JW, Zhan Z, Ji G, Sang Y, Zhou D, Li Y, Feng H, Cheng T
Signal transduction and targeted therapy 2021 Mar 31;6(1):129
Signal transduction and targeted therapy 2021 Mar 31;6(1):129
MYC promotes cancer progression by modulating m(6) A modifications to suppress target gene translation.
Wu G, Suo C, Yang Y, Shen S, Sun L, Li ST, Zhou Y, Yang D, Wang Y, Cai Y, Wang N, Zhang H, Yang YG, Cao J, Gao P
EMBO reports 2021 Mar 3;22(3):e51519
EMBO reports 2021 Mar 3;22(3):e51519
The CREB/KMT5A complex regulates PTP1B to modulate high glucose-induced endothelial inflammatory factor levels in diabetic nephropathy.
Huang T, Li X, Wang F, Lu L, Hou W, Zhu M, Miao C
Cell death & disease 2021 Mar 29;12(4):333
Cell death & disease 2021 Mar 29;12(4):333
Profiling PRMT methylome reveals roles of hnRNPA1 arginine methylation in RNA splicing and cell growth.
Li WJ, He YH, Yang JJ, Hu GS, Lin YA, Ran T, Peng BL, Xie BL, Huang MF, Gao X, Huang HH, Zhu HH, Ye F, Liu W
Nature communications 2021 Mar 29;12(1):1946
Nature communications 2021 Mar 29;12(1):1946
Angiomotin Counteracts the Negative Regulatory Effect of Host WWOX on Viral PPxY-Mediated Egress.
Liang J, Ruthel G, Sagum CA, Bedford MT, Sidhu SS, Sudol M, Jaladanki CK, Fan H, Freedman BD, Harty RN
Journal of virology 2021 Mar 25;95(8)
Journal of virology 2021 Mar 25;95(8)
Hispidulin inhibits proliferation, migration, and invasion by promoting autophagy via regulation of PPARγ activation in prostate cancer cells and xenograft models.
Wang Y, Guo S, Jia Y, Yu X, Mou R, Li X
Bioscience, biotechnology, and biochemistry 2021 Mar 24;85(4):786-797
Bioscience, biotechnology, and biochemistry 2021 Mar 24;85(4):786-797
Inhibition of lipogenesis and induction of apoptosis by valproic acid in prostate cancer cells via the C/EBPα/SREBP-1 pathway.
Pang B, Zhang J, Zhang X, Yuan J, Shi Y, Qiao L
Acta biochimica et biophysica Sinica 2021 Mar 2;53(3):354-364
Acta biochimica et biophysica Sinica 2021 Mar 2;53(3):354-364
Effects of transforming growth factor-β1 on odontoblastic differentiation in dental papilla cells is determined by IPO7 expression level.
Zhang Y, Zhang H, Yuan G, Yang G
Biochemical and biophysical research communications 2021 Mar 19;545:105-111
Biochemical and biophysical research communications 2021 Mar 19;545:105-111
hPER3 promotes adipogenesis via hHSP90AA1-mediated inhibition of Notch1 pathway.
Wan X, Zhu L, Zhao L, Peng L, Xiong J, Yang W, Yuan J, Liang F, Zhang K, Chen K
Cell death & disease 2021 Mar 19;12(4):301
Cell death & disease 2021 Mar 19;12(4):301
Identifying SLC27A5 as a potential prognostic marker of hepatocellular carcinoma by weighted gene co-expression network analysis and in vitro assays.
Zhang F, Xue M, Jiang X, Yu H, Qiu Y, Yu J, Yang F, Bao Z
Cancer cell international 2021 Mar 17;21(1):174
Cancer cell international 2021 Mar 17;21(1):174
PEG-GO@XN nanocomposite suppresses breast cancer metastasis via inhibition of mitochondrial oxidative phosphorylation and blockade of epithelial-to-mesenchymal transition.
Zhang J, Yan L, Wei P, Zhou R, Hua C, Xiao M, Tu Y, Gu Z, Wei T
European journal of pharmacology 2021 Mar 15;895:173866
European journal of pharmacology 2021 Mar 15;895:173866
PCGF3 promotes the proliferation and migration of non-small cell lung cancer cells via the PI3K/AKT signaling pathway.
Hu Y, Cheng Y, Jiang X, Zhang Y, Wang H, Ren H, Xu Y, Jiang J, Wang Q, Su H, Zhang B, Qiu X
Experimental cell research 2021 Mar 15;400(2):112496
Experimental cell research 2021 Mar 15;400(2):112496
The Effect of Hispidulin, a Flavonoid from Salvia plebeia, on Human Nasopharyngeal Carcinoma CNE-2Z Cell Proliferation, Migration, Invasion, and Apoptosis.
Dai Y, Sun X, Li B, Ma H, Wu P, Zhang Y, Zhu M, Li HM, Qin M, Wu CZ
Molecules (Basel, Switzerland) 2021 Mar 14;26(6)
Molecules (Basel, Switzerland) 2021 Mar 14;26(6)
Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.
Han D, Xu Y, Peng WP, Feng F, Wang Z, Gu C, Zhou X
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 12;27:e928547
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 12;27:e928547
Gastrodin ameliorates learning and memory impairment in rats with vascular dementia by promoting autophagy flux via inhibition of the Ca(2+)/CaMKII signal pathway.
Chen TT, Zhou X, Xu YN, Li Y, Wu XY, Xiang Q, Fu LY, Hu XX, Tao L, Shen XC
Aging 2021 Mar 10;13(7):9542-9565
Aging 2021 Mar 10;13(7):9542-9565
Cytotoxicity mechanisms of plumbagin in drug-resistant tongue squamous cell carcinoma.
Xue D, Zhou X, Qiu J
The Journal of pharmacy and pharmacology 2021 Mar 1;73(1):98-109
The Journal of pharmacy and pharmacology 2021 Mar 1;73(1):98-109
The deubiquitylase USP9X controls ribosomal stalling.
Clancy A, Heride C, Pinto-Fernández A, Elcocks H, Kallinos A, Kayser-Bricker KJ, Wang W, Smith V, Davis S, Fessler S, McKinnon C, Katz M, Hammonds T, Jones NP, O'Connell J, Follows B, Mischke S, Caravella JA, Ioannidis S, Dinsmore C, Kim S, Behrens A, Komander D, Kessler BM, Urbé S, Clague MJ
The Journal of cell biology 2021 Mar 1;220(3)
The Journal of cell biology 2021 Mar 1;220(3)
SZB120 Exhibits Immunomodulatory Effects by Targeting eIF2α to Suppress Th17 Cell Differentiation.
Chen L, Bai J, Peng D, Gao Y, Cai X, Zhang J, Tang S, Niu L, Sun Y, Lou F, Zhou H, Yin Q, Wang Z, Sun L, Du X, Xu Z, Wang H, Li Q, Wang H
Journal of immunology (Baltimore, Md. : 1950) 2021 Mar 1;206(5):953-962
Journal of immunology (Baltimore, Md. : 1950) 2021 Mar 1;206(5):953-962
Melatonin inhibits vascular endothelial cell pyroptosis by improving mitochondrial function via up-regulation and demethylation of UQCRC1.
Zeng J, Tao J, Xia L, Zeng Z, Chen J, Wang Z, Meng J, Liu L
Biochemistry and cell biology = Biochimie et biologie cellulaire 2021 Jun;99(3):339-347
Biochemistry and cell biology = Biochimie et biologie cellulaire 2021 Jun;99(3):339-347
A novel peptide promotes human trophoblast proliferation and migration through PI3K/Akt/mTOR signaling pathway.
Ling L, Yuan X, Liu X, Pei W, Li R
Annals of translational medicine 2021 Jun;9(12):981
Annals of translational medicine 2021 Jun;9(12):981
Ninjinyoeito improves anxiety behavior in neuropeptide Y deficient zebrafish.
Kawabe M, Hayashi A, Komatsu M, Inui A, Shiozaki K
Neuropeptides 2021 Jun;87:102136
Neuropeptides 2021 Jun;87:102136
Interleukin-24 as a Pulmonary Target Cytokine in Bronchopulmonary Dysplasia.
Gao R, Li Z, Ai D, Ma J, Chen C, Liu X
Cell biochemistry and biophysics 2021 Jun;79(2):311-320
Cell biochemistry and biophysics 2021 Jun;79(2):311-320
Promoterless, Nuclease-Free Genome Editing Confers a Growth Advantage for Corrected Hepatocytes in Mice With Methylmalonic Acidemia.
Chandler RJ, Venturoni LE, Liao J, Hubbard BT, Schneller JL, Hoffmann V, Gordo S, Zang S, Ko CW, Chau N, Chiang K, Kay MA, Barzel A, Venditti CP
Hepatology (Baltimore, Md.) 2021 Jun;73(6):2223-2237
Hepatology (Baltimore, Md.) 2021 Jun;73(6):2223-2237
NCOA4-mediated ferritinophagy promoted inflammatory responses in periodontitis.
Guo W, Zhao Y, Li H, Lei L
Journal of periodontal research 2021 Jun;56(3):523-534
Journal of periodontal research 2021 Jun;56(3):523-534
Sodium sulfite causes gastric mucosal cell death by inducing oxidative stress.
Oshimo M, Nakashima F, Kai K, Matsui H, Shibata T, Akagawa M
Free radical research 2021 Jun;55(6):731-743
Free radical research 2021 Jun;55(6):731-743
Golgi phosphoprotein 3 promotes the proliferation of gallbladder carcinoma cells via regulation of the NLRP3 inflammasome.
Zhu Z, Zhu Q, Cai D, Chen L, Xie W, Bai Y, Luo K
Oncology reports 2021 Jun;45(6)
Oncology reports 2021 Jun;45(6)
FMR1/circCHAF1A/miR-211-5p/HOXC8 feedback loop regulates proliferation and tumorigenesis via MDM2-dependent p53 signaling in GSCs.
Jiang Y, Wang Z, Ying C, Hu J, Zeng T, Gao L
Oncogene 2021 Jun;40(24):4094-4110
Oncogene 2021 Jun;40(24):4094-4110
SMAR1 attenuates the stemness of osteosarcoma cells via through suppressing ABCG2 transcriptional activity.
Xu H, Liu T, Li W, Yao Q
Environmental toxicology 2021 Jun;36(6):1090-1098
Environmental toxicology 2021 Jun;36(6):1090-1098
Small Interfering RNA Targeting DMP1 Protects Mice Against Blood-Brain Barrier Disruption and Brain Injury After Intracerebral Hemorrhage.
Shu Y, Huang J, Gao M, Gan S, Zhu S, Xu S, Yang Z, Liao Y, Lu W
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2021 Jun;30(6):105760
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2021 Jun;30(6):105760
Cellular microRNAs influence replication of H3N2 canine influenza virus in infected cells.
Xie X, Pang M, Liang S, Lin Y, Zhao Y, Qiu D, Liu J, Dong Y, Liu Y
Veterinary microbiology 2021 Jun;257:109083
Veterinary microbiology 2021 Jun;257:109083
Sparstolonin B exerts beneficial effects on prostate cancer by acting on the reactive oxygen species-mediated PI3K/AKT pathway.
Liu S, Hu J, Shi C, Sun L, Yan W, Song Y
Journal of cellular and molecular medicine 2021 Jun;25(12):5511-5524
Journal of cellular and molecular medicine 2021 Jun;25(12):5511-5524
Fructose-1,6-bisphosphatase aggravates oxidative stress-induced apoptosis in asthma by suppressing the Nrf2 pathway.
Hu J, Wang J, Li C, Shang Y
Journal of cellular and molecular medicine 2021 Jun;25(11):5001-5014
Journal of cellular and molecular medicine 2021 Jun;25(11):5001-5014
Phgdh serves a protective role in Il‑1β induced chondrocyte inflammation and oxidative‑stress damage.
Huang H, Liu K, Ou H, Qian X, Wan J
Molecular medicine reports 2021 Jun;23(6)
Molecular medicine reports 2021 Jun;23(6)
Exploration of the hepatoprotective effect and mechanism of magnesium isoglycyrrhizinate in mice with arsenic trioxide‑induced acute liver injury.
Liu M, Zheng B, Liu P, Zhang J, Chu X, Dong C, Shi J, Liang Y, Chu L, Liu Y, Han X
Molecular medicine reports 2021 Jun;23(6)
Molecular medicine reports 2021 Jun;23(6)
Resveratrol sensitizes A549 cells to irradiation damage via suppression of store-operated calcium entry with Orai1 and STIM1 downregulation.
Lele W, Lei L, Liting Q
Experimental and therapeutic medicine 2021 Jun;21(6):587
Experimental and therapeutic medicine 2021 Jun;21(6):587
Differential expression of protein disulfide isomerase (PDI) in regulating endometrial receptivity in humans.
Fernando SR, Kottawatta KSA, Jiang L, Chen X, Cheng KW, Wong BP, Ng EH, Yeung WS, Lee KF
Reproductive biology 2021 Jun;21(2):100498
Reproductive biology 2021 Jun;21(2):100498
miR-29a-3p-dependent COL3A1 and COL5A1 expression reduction assists sulforaphane to inhibit gastric cancer progression.
Han S, Wang Z, Liu J, Wang HD, Yuan Q
Biochemical pharmacology 2021 Jun;188:114539
Biochemical pharmacology 2021 Jun;188:114539
RRx-001 ameliorates inflammatory diseases by acting as a potent covalent NLRP3 inhibitor.
Chen Y, He H, Lin B, Chen Y, Deng X, Jiang W, Zhou R
Cellular & molecular immunology 2021 Jun;18(6):1425-1436
Cellular & molecular immunology 2021 Jun;18(6):1425-1436
Signal-regulatory protein alpha is an anti-viral entry factor targeting viruses using endocytic pathways.
Sarute N, Cheng H, Yan Z, Salas-Briceno K, Richner J, Rong L, Ross SR
PLoS pathogens 2021 Jun;17(6):e1009662
PLoS pathogens 2021 Jun;17(6):e1009662
SNX-3 mediates retromer-independent tubular endosomal recycling by opposing EEA-1-facilitated trafficking.
Tian Y, Kang Q, Shi X, Wang Y, Zhang N, Ye H, Xu Q, Xu T, Zhang R
PLoS genetics 2021 Jun;17(6):e1009607
PLoS genetics 2021 Jun;17(6):e1009607
Paricalcitol inhibits oxidative stress-induced cell senescence of the bile duct epithelium dependent on modulating Sirt1 pathway in cholestatic mice.
Jia R, Yang F, Yan P, Ma L, Yang L, Li L
Free radical biology & medicine 2021 Jun;169:158-168
Free radical biology & medicine 2021 Jun;169:158-168
Natural molecule Munronoid I attenuates LPS-induced acute lung injury by promoting the K48-linked ubiquitination and degradation of TAK1.
Ma X, Li X, Di Q, Zhao X, Zhang R, Xiao Y, Sun P, Tang H, Quan J, Xiao W, Chen W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111543
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111543
Tumor cell membrane-based peptide delivery system targeting the tumor microenvironment for cancer immunotherapy and diagnosis.
Meng X, Wang J, Zhou J, Tian Q, Qie B, Zhou G, Duan W, Zhu Y
Acta biomaterialia 2021 Jun;127:266-275
Acta biomaterialia 2021 Jun;127:266-275
Long non-coding RNA muskelin 1 antisense RNA (MKLN1-AS) is a potential diagnostic and prognostic biomarker and therapeutic target for hepatocellular carcinoma.
Guo C, Zhou S, Yi W, Yang P, Li O, Liu J, Peng C
Experimental and molecular pathology 2021 Jun;120:104638
Experimental and molecular pathology 2021 Jun;120:104638
Upregulation of ZHX2 predicts poor prognosis and is correlated with immune infiltration in gastric cancer.
Cheng A, Guo X, Dai X, Wang Z
FEBS open bio 2021 Jun;11(6):1785-1798
FEBS open bio 2021 Jun;11(6):1785-1798
Effect of SOCS3 on apoptosis of human trophoblasts via adjustment of the JAK2/STAT3 signaling pathway in preterm birth.
Yin Y, Qu L, Zhu D, Wu Y, Zhou X
Translational pediatrics 2021 Jun;10(6):1637-1646
Translational pediatrics 2021 Jun;10(6):1637-1646
CDK5 positively regulates Notch1 signaling in pancreatic cancer cells by phosphorylation.
Chu Q, Wang L, Zhang J, Wang W, Wang Y
Cancer medicine 2021 Jun;10(11):3689-3699
Cancer medicine 2021 Jun;10(11):3689-3699
PBRM1 Cooperates with YTHDF2 to Control HIF-1α Protein Translation.
Shmakova A, Frost M, Batie M, Kenneth NS, Rocha S
Cells 2021 Jun 8;10(6)
Cells 2021 Jun 8;10(6)
Multilevel regulation of Wnt signaling by Zic2 in colon cancer due to mutation of β-catenin.
Xu Z, Zheng J, Chen Z, Guo J, Li X, Wang X, Qu C, Yuan L, Cheng C, Sun X, Yu J
Cell death & disease 2021 Jun 7;12(6):584
Cell death & disease 2021 Jun 7;12(6):584
The combination of CUDC-907 and gilteritinib shows promising in vitro and in vivo antileukemic activity against FLT3-ITD AML.
Qiao X, Ma J, Knight T, Su Y, Edwards H, Polin L, Li J, Kushner J, Dzinic SH, White K, Wang J, Lin H, Wang Y, Wang L, Wang G, Taub JW, Ge Y
Blood cancer journal 2021 Jun 7;11(6):111
Blood cancer journal 2021 Jun 7;11(6):111
Hypericin-mediated photodynamic therapy inhibits growth of colorectal cancer cells via inducing S phase cell cycle arrest and apoptosis.
Hu J, Song J, Tang Z, Wei S, Chen L, Zhou R
European journal of pharmacology 2021 Jun 5;900:174071
European journal of pharmacology 2021 Jun 5;900:174071
Cisplatin remodels the tumor immune microenvironment via the transcription factor EB in ovarian cancer.
Liu W, Wang Y, Xie Y, Dai T, Fan M, Li C, Zou Y
Cell death discovery 2021 Jun 5;7(1):136
Cell death discovery 2021 Jun 5;7(1):136
The benzoate plant metabolite ethyl gallate prevents cellular- and vascular-lipid accumulation in experimental models of atherosclerosis.
Liu W, Liu J, Xing S, Pan X, Wei S, Zhou M, Li Z, Wang L, Bielicki JK
Biochemical and biophysical research communications 2021 Jun 4;556:65-71
Biochemical and biophysical research communications 2021 Jun 4;556:65-71
Alisol A 24-acetate protects against brain microvascular endothelial cells injury through inhibiting miR-92a-3p/tight junctions axis.
Lu L, Lu T, Shen J, Lv X, Wei W, Wang H, Xue X
Aging 2021 Jun 4;13(11):15353-15365
Aging 2021 Jun 4;13(11):15353-15365
Formin-like protein 2 promotes cell proliferation by a p27-related mechanism in human breast cancer cells.
Jiao X, Wang B, Feng C, Song S, Tian B, Zhou C, Gao X, Sun W, Liu P
BMC cancer 2021 Jun 30;21(1):760
BMC cancer 2021 Jun 30;21(1):760
Purification, characterization and anti-atherosclerotic effects of the polysaccharides from the fruiting body of Cordyceps militaris.
Yang X, Lin P, Wang J, Liu N, Yin F, Shen N, Guo S
International journal of biological macromolecules 2021 Jun 30;181:890-904
International journal of biological macromolecules 2021 Jun 30;181:890-904
Self-stabilizing regulation of deubiquitinating enzymes in an enzymatic activity-dependent manner.
Hou Z, Shi W, Feng J, Wang W, Zheng E, Lin H, Yu C, Li L
International journal of biological macromolecules 2021 Jun 30;181:1081-1091
International journal of biological macromolecules 2021 Jun 30;181:1081-1091
Breast tumor stiffness instructs bone metastasis via maintenance of mechanical conditioning.
Watson AW, Grant AD, Parker SS, Hill S, Whalen MB, Chakrabarti J, Harman MW, Roman MR, Forte BL, Gowan CC, Castro-Portuguez R, Stolze LK, Franck C, Cusanovich DA, Zavros Y, Padi M, Romanoski CE, Mouneimne G
Cell reports 2021 Jun 29;35(13):109293
Cell reports 2021 Jun 29;35(13):109293
Neu1 deficiency induces abnormal emotional behavior in zebrafish.
Ikeda A, Komamizu M, Hayashi A, Yamasaki C, Okada K, Kawabe M, Komatsu M, Shiozaki K
Scientific reports 2021 Jun 29;11(1):13477
Scientific reports 2021 Jun 29;11(1):13477
Thymosin β4 reverses phenotypic polarization of glial cells and cognitive impairment via negative regulation of NF-κB signaling axis in APP/PS1 mice.
Wang M, Feng LR, Li ZL, Ma KG, Chang KW, Chen XL, Yang PB, Ji SF, Ma YB, Han H, Ruganzua JB, Yang WN, Qian YH
Journal of neuroinflammation 2021 Jun 28;18(1):146
Journal of neuroinflammation 2021 Jun 28;18(1):146
The Anti-Tumor Effect and Underlying Apoptotic Mechanism of Ginsenoside Rk1 and Rg5 in Human Liver Cancer Cells.
Chen C, Lv Q, Li Y, Jin YH
Molecules (Basel, Switzerland) 2021 Jun 27;26(13)
Molecules (Basel, Switzerland) 2021 Jun 27;26(13)
DUSP1 overexpression attenuates renal tubular mitochondrial dysfunction by restoring Parkin-mediated mitophagy in diabetic nephropathy.
Lu C, Wu B, Liao Z, Xue M, Zou Z, Feng J, Sheng J
Biochemical and biophysical research communications 2021 Jun 25;559:141-147
Biochemical and biophysical research communications 2021 Jun 25;559:141-147
LncRNA CARMN overexpression promotes prognosis and chemosensitivity of triple negative breast cancer via acting as miR143-3p host gene and inhibiting DNA replication.
Sheng X, Dai H, Du Y, Peng J, Sha R, Yang F, Zhou L, Lin Y, Xu S, Wu Y, Yin W, Lu J
Journal of experimental & clinical cancer research : CR 2021 Jun 23;40(1):205
Journal of experimental & clinical cancer research : CR 2021 Jun 23;40(1):205
Binding of Benzo[a]pyrene Alters the Bioreactivity of Fine Biochar Particles toward Macrophages Leading to Deregulated Macrophagic Defense and Autophagy.
Ma J, Liu X, Yang Y, Qiu J, Dong Z, Ren Q, Zuo YY, Xia T, Chen W, Liu S
ACS nano 2021 Jun 22;15(6):9717-9731
ACS nano 2021 Jun 22;15(6):9717-9731
LINC00842 inactivates transcription co-regulator PGC-1α to promote pancreatic cancer malignancy through metabolic remodelling.
Huang X, Pan L, Zuo Z, Li M, Zeng L, Li R, Ye Y, Zhang J, Wu G, Bai R, Zhuang L, Wei L, Zheng Y, Su J, Deng J, Deng S, Zhang S, Zhu S, Che X, Wang C, Wu C, Chen R, Lin D, Zheng J
Nature communications 2021 Jun 22;12(1):3830
Nature communications 2021 Jun 22;12(1):3830
LINC_00355 promotes gastric cancer progression by upregulating PHF19 expression through sponging miR-15a-5p.
Zhang J, Lv W, Liu Y, Fu W, Chen B, Ma Q, Gao X
BMC cancer 2021 Jun 2;21(1):657
BMC cancer 2021 Jun 2;21(1):657
Colorectal cancer cells utilize autophagy to maintain mitochondrial metabolism for cell proliferation under nutrient stress.
Devenport SN, Singhal R, Radyk MD, Taranto JG, Kerk SA, Chen B, Goyert JW, Jain C, Das NK, Oravecz-Wilson K, Zhang L, Greenson JK, Chen YE, Soleimanpour SA, Reddy P, Lyssiotis CA, Shah YM
JCI insight 2021 Jun 17;6(14)
JCI insight 2021 Jun 17;6(14)
Isorhamnetin Promotes Estrogen Biosynthesis and Proliferation in Porcine Granulosa Cells via the PI3K/Akt Signaling Pathway.
Li X, Chen H, Zhang Z, Xu D, Duan J, Li X, Yang L, Hua R, Cheng J, Li Q
Journal of agricultural and food chemistry 2021 Jun 16;69(23):6535-6542
Journal of agricultural and food chemistry 2021 Jun 16;69(23):6535-6542
Protective effect of scorpion venom heat-resistant synthetic peptide against PM(2.5)-induced microglial polarization via TLR4-mediated autophagy activating PI3K/AKT/NF-κB signaling pathway.
Xu X, Xu H, Ren F, Huang L, Xu J, Li F
Journal of neuroimmunology 2021 Jun 15;355:577567
Journal of neuroimmunology 2021 Jun 15;355:577567
HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron.
Singhal R, Mitta SR, Das NK, Kerk SA, Sajjakulnukit P, Solanki S, Andren A, Kumar R, Olive KP, Banerjee R, Lyssiotis CA, Shah YM
The Journal of clinical investigation 2021 Jun 15;131(12)
The Journal of clinical investigation 2021 Jun 15;131(12)
Aerobic Exercise Improves Mitochondrial Function in Sarcopenia Mice Through Sestrin2 in an AMPKα2-Dependent Manner.
Liu S, Yu C, Xie L, Niu Y, Fu L
The journals of gerontology. Series A, Biological sciences and medical sciences 2021 Jun 14;76(7):1161-1168
The journals of gerontology. Series A, Biological sciences and medical sciences 2021 Jun 14;76(7):1161-1168
The engineered expression of secreted HSPB5-Fc in CHO cells exhibits cytoprotection in vitro.
Li J, Yu J, Xue W, Huang H, Yan L, Sang F, An S, Zhang J, Wang M, Zhang J, Li H, Cui X, He J, Hu Y
BMC biotechnology 2021 Jun 14;21(1):39
BMC biotechnology 2021 Jun 14;21(1):39
Protective effects of 4-octyl itaconate against inflammatory response in angiotensin II-induced oxidative stress in human primary retinal pigment epithelium.
Fu X, Wu M, Zhou X
Biochemical and biophysical research communications 2021 Jun 11;557:77-84
Biochemical and biophysical research communications 2021 Jun 11;557:77-84
Protective Effects of Bone Marrow Mesenchymal Stem Cells (BMMSCS) Combined with Normothermic Machine Perfusion on Liver Grafts Donated After Circulatory Death via Reducing the Ferroptosis of Hepatocytes.
Sun D, Yang L, Zheng W, Cao H, Wu L, Song H
Medical science monitor : international medical journal of experimental and clinical research 2021 Jun 11;27:e930258
Medical science monitor : international medical journal of experimental and clinical research 2021 Jun 11;27:e930258
Central nervous system-targeted adeno-associated virus gene therapy in methylmalonic acidemia.
May FJ, Head PE, Venturoni LE, Chandler RJ, Venditti CP
Molecular therapy. Methods & clinical development 2021 Jun 11;21:765-776
Molecular therapy. Methods & clinical development 2021 Jun 11;21:765-776
LncRNA CTD-2528L19.6 prevents the progression of IPF by alleviating fibroblast activation.
Chen T, Guo Y, Wang J, Ai L, Ma L, He W, Li Z, Yu X, Li J, Fan X, Gu Y, Liang H
Cell death & disease 2021 Jun 10;12(6):600
Cell death & disease 2021 Jun 10;12(6):600
Resveratrol and its derivative pterostilbene ameliorate intestine injury in intrauterine growth-retarded weanling piglets by modulating redox status and gut microbiota.
Chen Y, Zhang H, Chen Y, Jia P, Ji S, Zhang Y, Wang T
Journal of animal science and biotechnology 2021 Jun 10;12(1):70
Journal of animal science and biotechnology 2021 Jun 10;12(1):70
Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance.
Liu Y, Liang G, Xu H, Dong W, Dong Z, Qiu Z, Zhang Z, Li F, Huang Y, Li Y, Wu J, Yin S, Zhang Y, Guo P, Liu J, Xi JJ, Jiang P, Han D, Yang CG, Xu MM
Cell metabolism 2021 Jun 1;33(6):1221-1233.e11
Cell metabolism 2021 Jun 1;33(6):1221-1233.e11
Hyaluronic acid/polyethyleneimine nanoparticles loaded with copper ion and disulfiram for esophageal cancer.
Xu R, Zhang K, Liang J, Gao F, Li J, Guan F
Carbohydrate polymers 2021 Jun 1;261:117846
Carbohydrate polymers 2021 Jun 1;261:117846
Galectin-9 Targets NLRP3 for Autophagic Degradation to Limit Inflammation.
Wang W, Qin Y, Song H, Wang L, Jia M, Zhao C, Gong M, Zhao W
Journal of immunology (Baltimore, Md. : 1950) 2021 Jun 1;206(11):2692-2699
Journal of immunology (Baltimore, Md. : 1950) 2021 Jun 1;206(11):2692-2699
Butyrate enhances CPT1A activity to promote fatty acid oxidation and iTreg differentiation.
Hao F, Tian M, Zhang X, Jin X, Jiang Y, Sun X, Wang Y, Peng P, Liu J, Xia C, Feng Y, Wei M
Proceedings of the National Academy of Sciences of the United States of America 2021 Jun 1;118(22)
Proceedings of the National Academy of Sciences of the United States of America 2021 Jun 1;118(22)
25-Hydroxycholesterol mitigates hepatic ischemia reperfusion injury via mediating mitophagy.
Cao Q, Luo J, Xiong Y, Liu Z, Ye Q
International immunopharmacology 2021 Jul;96:107643
International immunopharmacology 2021 Jul;96:107643
Targeting TSP-1 decreased periodontitis by attenuating extracellular matrix degradation and alveolar bone destruction.
Liu X, Jin J, Liu Y, Shen Z, Zhao R, Ou L, Xing T
International immunopharmacology 2021 Jul;96:107618
International immunopharmacology 2021 Jul;96:107618
Pirfenidone mediates cigarette smoke extract induced inflammation and oxidative stress in vitro and in vivo.
Ma Y, Luo L, Liu X, Li H, Zeng Z, He X, Zhan Z, Chen Y
International immunopharmacology 2021 Jul;96:107593
International immunopharmacology 2021 Jul;96:107593
A neutral polysaccharide from Ophiocordyceps lanpingensis restrains cisplatin-induced nephrotoxicity.
Zhou S, Zhou Y, Yu J, Jiang L, Xiang Y, Wang J, Du Y, Cui X, Ge F
Food science & nutrition 2021 Jul;9(7):3602-3616
Food science & nutrition 2021 Jul;9(7):3602-3616
YAP/TEAD4-induced KIF4A contributes to the progression and worse prognosis of esophageal squamous cell carcinoma.
Li Y, Zhu X, Yang M, Wang Y, Li J, Fang J, Guo W, Ma S, Guan F
Molecular carcinogenesis 2021 Jul;60(7):440-454
Molecular carcinogenesis 2021 Jul;60(7):440-454
Thioredoxin-1 Rescues MPP(+)/MPTP-Induced Ferroptosis by Increasing Glutathione Peroxidase 4.
Bai L, Yan F, Deng R, Gu R, Zhang X, Bai J
Molecular neurobiology 2021 Jul;58(7):3187-3197
Molecular neurobiology 2021 Jul;58(7):3187-3197
miR-671-5p Attenuates Neuroinflammation via Suppressing NF-κB Expression in an Acute Ischemic Stroke Model.
Deng L, Guo Y, Liu J, Wang X, Chen S, Wang Q, Rao J, Wang Y, Zuo T, Hu Q, Zhao X, Dong Z
Neurochemical research 2021 Jul;46(7):1801-1813
Neurochemical research 2021 Jul;46(7):1801-1813
DHCR24 Knockdown Lead to Hyperphosphorylation of Tau at Thr181, Thr231, Ser262, Ser396, and Ser422 Sites by Membrane Lipid-Raft Dependent PP2A Signaling in SH-SY5Y Cells.
Qi Z, Zhang Y, Yao K, Zhang M, Xu Y, Zhang J, Bai X, Zu H
Neurochemical research 2021 Jul;46(7):1627-1640
Neurochemical research 2021 Jul;46(7):1627-1640
Hawthorn polyphenols, D-chiro-inositol, and epigallocatechin gallate exert a synergistic hypoglycemic effect.
Xin C, Zhao M, Wang J, Wang Z
Journal of food biochemistry 2021 Jul;45(7):e13771
Journal of food biochemistry 2021 Jul;45(7):e13771
EZH2 regulates expression of FOXC1 by mediating H3K27me3 in breast cancers.
Zheng XJ, Li W, Yi J, Liu JY, Ren LW, Zhu XM, Liu SW, Wang JH, Du GH
Acta pharmacologica Sinica 2021 Jul;42(7):1171-1179
Acta pharmacologica Sinica 2021 Jul;42(7):1171-1179
The role of the HIF-1α/ALYREF/PKM2 axis in glycolysis and tumorigenesis of bladder cancer.
Wang JZ, Zhu W, Han J, Yang X, Zhou R, Lu HC, Yu H, Yuan WB, Li PC, Tao J, Lu Q, Wei JF, Yang H
Cancer communications (London, England) 2021 Jul;41(7):560-575
Cancer communications (London, England) 2021 Jul;41(7):560-575
Sestrin2 protects against traumatic brain injury by reinforcing the activation of Nrf2 signaling.
Liu X, Li M, Zhu J, Huang W, Song J
Human & experimental toxicology 2021 Jul;40(7):1095-1111
Human & experimental toxicology 2021 Jul;40(7):1095-1111
Targeted radioimmunotherapy with the iodine-131-labeled caerin 1.1 peptide for human anaplastic thyroid cancer in nude mice.
Lin R, Ma B, Liu N, Zhang L, He T, Liu X, Chen T, Liu W, Liang Y, Wang T, Ni G, Liu X, Yang N, Zhang J, Yuan J
Annals of nuclear medicine 2021 Jul;35(7):811-822
Annals of nuclear medicine 2021 Jul;35(7):811-822
Hepcidin sequesters iron to sustain nucleotide metabolism and mitochondrial function in colorectal cancer epithelial cells.
Schwartz AJ, Goyert JW, Solanki S, Kerk SA, Chen B, Castillo C, Hsu PP, Do BT, Singhal R, Dame MK, Lee HJ, Spence JR, Lakhal-Littleton S, Vander Heiden MG, Lyssiotis CA, Xue X, Shah YM
Nature metabolism 2021 Jul;3(7):969-982
Nature metabolism 2021 Jul;3(7):969-982
TCDD induced lipid accumulation by impairment of autophagic flux in THP-1 macrophages.
Lu J, Liu M, Fan Y, Zheng H, Guan S
Environmental science and pollution research international 2021 Jul;28(27):36053-36059
Environmental science and pollution research international 2021 Jul;28(27):36053-36059
NT5DC2 promotes leiomyosarcoma tumour cell growth via stabilizing unpalmitoylated TEAD4 and generating a positive feedback loop.
Hu B, Zhou S, Hu X, Zhang H, Lan X, Li M, Wang Y, Hu Q
Journal of cellular and molecular medicine 2021 Jul;25(13):5976-5987
Journal of cellular and molecular medicine 2021 Jul;25(13):5976-5987
Comparison of multi-walled carbon nanotubes and halloysite nanotubes on lipid profiles in human umbilical vein endothelial cells.
Liu Y, Hu Q, Huang C, Cao Y
NanoImpact 2021 Jul;23:100333
NanoImpact 2021 Jul;23:100333
TLR2 senses the SARS-CoV-2 envelope protein to produce inflammatory cytokines.
Zheng M, Karki R, Williams EP, Yang D, Fitzpatrick E, Vogel P, Jonsson CB, Kanneganti TD
Nature immunology 2021 Jul;22(7):829-838
Nature immunology 2021 Jul;22(7):829-838
Effect of the interference with DRP1 expression on the biological characteristics of glioma stem cells.
Zhang L, Cao H, Tao H, Yang J, Gong W, Hu Q
Experimental and therapeutic medicine 2021 Jul;22(1):696
Experimental and therapeutic medicine 2021 Jul;22(1):696
A conserved ubiquitin- and ESCRT-dependent pathway internalizes human lysosomal membrane proteins for degradation.
Zhang W, Yang X, Chen L, Liu YY, Venkatarangan V, Reist L, Hanson P, Xu H, Wang Y, Li M
PLoS biology 2021 Jul;19(7):e3001361
PLoS biology 2021 Jul;19(7):e3001361
C1orf61 promotes hepatocellular carcinoma metastasis and increases the therapeutic response to sorafenib.
Yu Y, Wang Z, Huang Z, Tang X, Huang X, Li W
Biochimica et biophysica acta. Molecular cell research 2021 Jul;1868(8):119048
Biochimica et biophysica acta. Molecular cell research 2021 Jul;1868(8):119048
Visfatin regulates Pg LPS-induced proinflammatory/prodegradative effects in healthy and inflammatory periodontal cells partially via NF-κB pathway.
Yao S, Jiang C, Zhang H, Gao X, Guo Y, Cao Z
Biochimica et biophysica acta. Molecular cell research 2021 Jul;1868(8):119042
Biochimica et biophysica acta. Molecular cell research 2021 Jul;1868(8):119042
Ets-2 deletion in myeloid cells attenuates IL-1α-mediated inflammatory disease caused by a Ptpn6 point mutation.
Tartey S, Gurung P, Karki R, Burton A, Hertzog P, Kanneganti TD
Cellular & molecular immunology 2021 Jul;18(7):1798-1808
Cellular & molecular immunology 2021 Jul;18(7):1798-1808
Mycobacterium tuberculosis inhibits the NLRP3 inflammasome activation via its phosphokinase PknF.
Rastogi S, Ellinwood S, Augenstreich J, Mayer-Barber KD, Briken V
PLoS pathogens 2021 Jul;17(7):e1009712
PLoS pathogens 2021 Jul;17(7):e1009712
DENV NS1 and MMP-9 cooperate to induce vascular leakage by altering endothelial cell adhesion and tight junction.
Pan P, Li G, Shen M, Yu Z, Ge W, Lao Z, Fan Y, Chen K, Ding Z, Wang W, Wan P, Shereen MA, Luo Z, Chen X, Zhang Q, Lin L, Wu J
PLoS pathogens 2021 Jul;17(7):e1008603
PLoS pathogens 2021 Jul;17(7):e1008603
Chemical conjugation of FITC to track silica nanoparticles in vivo and in vitro: An emerging method to assess the reproductive toxicity of industrial nanomaterials.
Li J, Tian J, Yin H, Peng Y, Liu S, Yao S, Zhang L
Environment international 2021 Jul;152:106497
Environment international 2021 Jul;152:106497
Andrographolide Attenuates Gut-Brain-Axis Associated Pathology in Gulf War Illness by Modulating Bacteriome-Virome Associated Inflammation and Microglia-Neuron Proinflammatory Crosstalk.
Saha P, Skidmore PT, Holland LA, Mondal A, Bose D, Seth RK, Sullivan K, Janulewicz PA, Horner R, Klimas N, Nagarkatti M, Nagarkatti P, Lim ES, Chatterjee S
Brain sciences 2021 Jul 9;11(7)
Brain sciences 2021 Jul 9;11(7)
ets1 associates with KMT5A to participate in high glucose-mediated EndMT via upregulation of PFN2 expression in diabetic nephropathy.
Lu L, Zhong Z, Gu J, Nan K, Zhu M, Miao C
Molecular medicine (Cambridge, Mass.) 2021 Jul 8;27(1):74
Molecular medicine (Cambridge, Mass.) 2021 Jul 8;27(1):74
Inhibition of xCT suppresses the efficacy of anti-PD-1/L1 melanoma treatment through exosomal PD-L1-induced macrophage M2 polarization.
Liu N, Zhang J, Yin M, Liu H, Zhang X, Li J, Yan B, Guo Y, Zhou J, Tao J, Hu S, Chen X, Peng C
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Jul 7;29(7):2321-2334
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Jul 7;29(7):2321-2334
Baicalein Delays H(2)O(2)-Induced Astrocytic Senescence through Inhibition of Senescence-Associated Secretory Phenotype (SASP), Suppression of JAK2/STAT1/NF-κB Pathway, and Regulation of Leucine Metabolism.
Gao L, Zheng WG, Wu XK, Du GH, Qin XM
ACS chemical neuroscience 2021 Jul 7;12(13):2320-2335
ACS chemical neuroscience 2021 Jul 7;12(13):2320-2335
Piperlongumine inhibits migration and proliferation of castration-resistant prostate cancer cells via triggering persistent DNA damage.
Zhang DF, Yang ZC, Chen JQ, Jin XX, Qiu YD, Chen XJ, Shi HY, Liu ZG, Wang MS, Liang G, Zheng XH
BMC complementary medicine and therapies 2021 Jul 6;21(1):195
BMC complementary medicine and therapies 2021 Jul 6;21(1):195
Baicalein inhibits RLS3-induced ferroptosis in melanocytes.
Yang M, Li X, Li H, Zhang X, Liu X, Song Y
Biochemical and biophysical research communications 2021 Jul 5;561:65-72
Biochemical and biophysical research communications 2021 Jul 5;561:65-72
Melatonin alleviates Ochratoxin A-induced liver inflammation involved intestinal microbiota homeostasis and microbiota-independent manner.
Xia D, Yang L, Li Y, Chen J, Zhang X, Wang H, Zhai S, Jiang X, Meca G, Wang S, Huang L, Zhu S, Fu Y, Ma W, Zhu Y, Ye H, Wang W
Journal of hazardous materials 2021 Jul 5;413:125239
Journal of hazardous materials 2021 Jul 5;413:125239
mPEG(2k)-PCL(x) Polymeric Micelles Influence Pharmacokinetics and Hypoglycemic Efficacy of Metformin through Inhibition of Organic Cation Transporters in Rats.
Zhang Y, Sun M, Jian S, Huang J, Xiao C, Zhang X, Hu R, Si L
Molecular pharmaceutics 2021 Jul 5;18(7):2586-2599
Molecular pharmaceutics 2021 Jul 5;18(7):2586-2599
The intrinsic role and mechanism of tumor expressed-CD38 on lung adenocarcinoma progression.
Gao L, Liu Y, Du X, Ma S, Ge M, Tang H, Han C, Zhao X, Liu Y, Shao Y, Wu Z, Zhang L, Meng F, Xiao-Feng Qin F
Cell death & disease 2021 Jul 5;12(7):680
Cell death & disease 2021 Jul 5;12(7):680
Probiotic-fermented black tartary buckwheat alleviates hyperlipidemia and gut microbiota dysbiosis in rats fed with a high-fat diet.
Ren Y, Wu S, Xia Y, Huang J, Ye J, Xuan Z, Li P, Du B
Food & function 2021 Jul 5;12(13):6045-6057
Food & function 2021 Jul 5;12(13):6045-6057
L-Theanine regulates glutamine metabolism and immune function by binding to cannabinoid receptor 1.
Liu A, Lin L, Xu W, Gong Z, Liu Z, Xiao W
Food & function 2021 Jul 5;12(13):5755-5769
Food & function 2021 Jul 5;12(13):5755-5769
NR1D1 suppressed the growth of ovarian cancer by abrogating the JAK/STAT3 signaling pathway.
Wang H, Fu Y
BMC cancer 2021 Jul 30;21(1):871
BMC cancer 2021 Jul 30;21(1):871
Anti-anemia drug FG4592 retards the AKI-to-CKD transition by improving vascular regeneration and antioxidative capability.
Wu M, Chen W, Miao M, Jin Q, Zhang S, Bai M, Fan J, Zhang Y, Zhang A, Jia Z, Huang S
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1707-1726
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1707-1726
Glycoursodeoxycholic acid ameliorates diet-induced metabolic disorders with inhibiting endoplasmic reticulum stress.
Cheng L, Chen T, Guo M, Liu P, Qiao X, Wei Y, She J, Li B, Xi W, Zhou J, Yuan Z, Wu Y, Liu J
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1689-1706
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1689-1706
Subregion-Specific Regulation of Dopamine D1 Receptor Signaling in the Striatum: Implication for L-DOPA-Induced Dyskinesia.
Sugiyama K, Kuroiwa M, Shuto T, Ohnishi YN, Kawahara Y, Miyamoto Y, Fukuda T, Nishi A
The Journal of neuroscience : the official journal of the Society for Neuroscience 2021 Jul 28;41(30):6388-6414
The Journal of neuroscience : the official journal of the Society for Neuroscience 2021 Jul 28;41(30):6388-6414
Growth Hormone Receptor (GHR) 6Ω Pseudoexon Activation: a Novel Cause of Severe Growth Hormone Insensitivity.
Cottrell E, Maharaj A, Williams J, Chatterjee S, Cirillo G, Miraglia Del Giudice E, Festa A, Palumbo S, Capalbo D, Salerno M, Pignata C, Savage MO, Schilbach K, Bidlingmaier M, Hwa V, Metherell LA, Grandone A, Storr HL
The Journal of clinical endocrinology and metabolism 2021 Jul 28;
The Journal of clinical endocrinology and metabolism 2021 Jul 28;
HELLS serves as a poor prognostic biomarker and its downregulation reserves the malignant phenotype in pancreatic cancer.
Wang FJ, Jing YH, Cheng CS, Cao ZQ, Jiao JY, Chen Z
BMC medical genomics 2021 Jul 27;14(1):189
BMC medical genomics 2021 Jul 27;14(1):189
Serum exosomes from young rats improve the reduced osteogenic differentiation of BMSCs in aged rats with osteoporosis after fatigue loading in vivo.
Xun J, Li C, Liu M, Mei Y, Zhou Q, Wu B, Xie F, Liu Y, Dai R
Stem cell research & therapy 2021 Jul 27;12(1):424
Stem cell research & therapy 2021 Jul 27;12(1):424
Nuclear iASPP determines cell fate by selectively inhibiting either p53 or NF-κB.
Ge W, Wang Y, Zheng S, Zhao D, Wang X, Zhang X, Hu Y
Cell death discovery 2021 Jul 26;7(1):195
Cell death discovery 2021 Jul 26;7(1):195
Integrated analysis of m(6)A mRNA methylation in rats with monocrotaline-induced pulmonary arterial hypertension.
Zeng Y, Huang T, Zuo W, Wang D, Xie Y, Wang X, Xiao Z, Chen Z, Liu Q, Liu N, Xiao Y
Aging 2021 Jul 26;13(14):18238-18256
Aging 2021 Jul 26;13(14):18238-18256
Effects of Loblolly Pine Biochar and Wood Vinegar on Poultry Litter Nutrients and Microbial Abundance.
Mohammadi-Aragh MK, Stokes CE, Street JT, Linhoss JE
Animals : an open access journal from MDPI 2021 Jul 26;11(8)
Animals : an open access journal from MDPI 2021 Jul 26;11(8)
Phenethylamine in chlorella alleviates high-fat diet-induced mouse liver damage by regulating generation of methylglyoxal.
Zheng Y, Martin-Morales A, Wang J, Fujishima M, Okumura E, Sato K
NPJ science of food 2021 Jul 23;5(1):22
NPJ science of food 2021 Jul 23;5(1):22
Hypoxic preconditioning rejuvenates mesenchymal stem cells and enhances neuroprotection following intracerebral hemorrhage via the miR-326-mediated autophagy.
Liu J, He J, Ge L, Xiao H, Huang Y, Zeng L, Jiang Z, Lu M, Hu Z
Stem cell research & therapy 2021 Jul 22;12(1):413
Stem cell research & therapy 2021 Jul 22;12(1):413
VALD-3, a Schiff base ligand synthesized from o-vanillin derivatives, induces cell cycle arrest and apoptosis in breast cancer cells by inhibiting the Wnt/β-catenin pathway.
Li H, Dang C, Tai X, Xue L, Meng Y, Ma S, Zhang J
Scientific reports 2021 Jul 22;11(1):14985
Scientific reports 2021 Jul 22;11(1):14985
Lactate secreted by PKM2 upregulation promotes Galectin-9-mediated immunosuppression via inhibiting NF-κB pathway in HNSCC.
Chang H, Xu Q, Li J, Li M, Zhang Z, Ma H, Yang X
Cell death & disease 2021 Jul 21;12(8):725
Cell death & disease 2021 Jul 21;12(8):725
Spodoptera frugiperda mRNA export factor interacts with and mediates the nuclear import of Autographa californica multiple nucleopolyhedrovirus ORF34 (Ac34).
Tang Z, Luo W, Huang Z, Yuan M, Wu W, Yang K
Virus research 2021 Jul 2;299:198438
Virus research 2021 Jul 2;299:198438
Establishment of a specific in vivo Cu(Ⅰ) reporting system based on metallothionein screening.
Ma M, Qiu B, Jin J, Wang J, Nie Y, Liang Y, Yu Z, Teng CB
Metallomics : integrated biometal science 2021 Jul 2;13(7)
Metallomics : integrated biometal science 2021 Jul 2;13(7)
Potential effect of EGCG on the anti-tumor efficacy of metformin in melanoma cells.
Xu A, Lee J, Zhao Y, Wang Y, Li X, Xu P
Journal of Zhejiang University. Science. B 2021 Jul 15;22(7):548-562
Journal of Zhejiang University. Science. B 2021 Jul 15;22(7):548-562
Decreased expression of the clock gene Bmal1 is involved in the pathogenesis of temporal lobe epilepsy.
Wu H, Liu Y, Liu L, Meng Q, Du C, Li K, Dong S, Zhang Y, Li H, Zhang H
Molecular brain 2021 Jul 14;14(1):113
Molecular brain 2021 Jul 14;14(1):113
p53 deficiency induces MTHFD2 transcription to promote cell proliferation and restrain DNA damage.
Li G, Wu J, Li L, Jiang P
Proceedings of the National Academy of Sciences of the United States of America 2021 Jul 13;118(28)
Proceedings of the National Academy of Sciences of the United States of America 2021 Jul 13;118(28)
Cyclophilin A Inhibits Human Respiratory Syncytial Virus (RSV) Replication by Binding to RSV-N through Its PPIase Activity.
Liang W, Zhang Y, Li M, Al-Shaebi F, Li J, Zhang J, Wei L
Journal of virology 2021 Jul 12;95(15):e0056321
Journal of virology 2021 Jul 12;95(15):e0056321
Stimuli-Responsive and Highly Penetrable Nanoparticles as a Multifunctional Nanoplatform for Boosting Nonsmall Cell Lung Cancer siRNA Therapy.
Shi M, Wang Y, Zhao X, Zhang J, Hu H, Qiao M, Zhao X, Chen D
ACS biomaterials science & engineering 2021 Jul 12;7(7):3141-3155
ACS biomaterials science & engineering 2021 Jul 12;7(7):3141-3155
Activation of Adenosine A(1) Receptor in Ischemic Stroke: Neuroprotection by Tetrahydroxy Stilbene Glycoside as an Agonist.
Ruan L, Li G, Zhao W, Meng H, Zheng Q, Wang J
Antioxidants (Basel, Switzerland) 2021 Jul 12;10(7)
Antioxidants (Basel, Switzerland) 2021 Jul 12;10(7)
The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability.
Pan Q, Zhong S, Wang H, Wang X, Li N, Li Y, Zhang G, Yuan H, Lian Y, Chen Q, Han Y, Guo J, Liu Q, Qiu T, Jiang J, Li Q, Tan M, Yin H, Peng J, Xiao Y, Qin J
Molecular cell 2021 Jul 1;81(13):2736-2751.e8
Molecular cell 2021 Jul 1;81(13):2736-2751.e8
Evaluating the protective effects of individual or combined ginsenoside compound K and the downregulation of soluble epoxide hydrolase expression against sodium valproate-induced liver cell damage.
Zhou L, Zeng X, Rao T, Tan Z, Zhou G, Ouyang D, Chen L
Toxicology and applied pharmacology 2021 Jul 1;422:115555
Toxicology and applied pharmacology 2021 Jul 1;422:115555
MicroRNA-363-3p promotes apoptosis in response to cadmium-induced renal injury by down-regulating phosphoinositide 3-kinase expression.
Chen J, Lai W, Deng Y, Liu M, Dong M, Liu Z, Wang T, Li X, Zhao Z, Yin X, Yang J, Yu R, Liu L
Toxicology letters 2021 Jul 1;345:12-23
Toxicology letters 2021 Jul 1;345:12-23
p55PIK deficiency and its NH(2)-terminal derivative inhibit inflammation and emphysema in COPD mouse model.
Wang T, Du X, Wang Z, Gu Y, Huang Q, Wu J, Zhan Y, Chen J, Xiao C, Xie J
American journal of physiology. Lung cellular and molecular physiology 2021 Jul 1;321(1):L159-L173
American journal of physiology. Lung cellular and molecular physiology 2021 Jul 1;321(1):L159-L173
Novel functional variants in the Notch pathway and survival of Chinese colorectal cancer.
Qu X, Zhao L, Wang M, Zhang R, Cheng L, Qiu L, Tong X, Cai S, Wei Q, Li Q
International journal of cancer 2021 Jul 1;149(1):84-96
International journal of cancer 2021 Jul 1;149(1):84-96
Alterations of GABA B receptors in the APP/PS1 mouse model of Alzheimer's disease.
Salazar AM, Leisgang AM, Ortiz AA, Murtishaw AS, Kinney JW
Neurobiology of aging 2021 Jan;97:129-143
Neurobiology of aging 2021 Jan;97:129-143
Identification and validation of L Antigen Family Member 3 as an immune-related biomarker associated with the progression of papillary thyroid cancer.
Dong X, Yang Q, Gu J, Lv S, Song D, Chen D, Song J, Zhang X, Huang D
International immunopharmacology 2021 Jan;90:107267
International immunopharmacology 2021 Jan;90:107267
Postnatal overfeeding induces hepatic microRNA-221 expression and impairs the PI3K/AKT pathway in adult male rats.
Huang F, Zhu P, Wang J, Chen J, Lin W
Pediatric research 2021 Jan;89(1):143-149
Pediatric research 2021 Jan;89(1):143-149
Uncaria rhynchophylla ameliorates unpredictable chronic mild stress-induced depression in mice via activating 5-HT(1A) receptor: Insights from transcriptomics.
Qiao YL, Zhou JJ, Liang JH, Deng XP, Zhang ZJ, Huang HL, Li S, Dai SF, Liu CQ, Luan ZL, Yu ZL, Sun CP, Ma XC
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jan;81:153436
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jan;81:153436
Regulation of branched-chain amino acid metabolism by hypoxia-inducible factor in glioblastoma.
Zhang B, Chen Y, Shi X, Zhou M, Bao L, Hatanpaa KJ, Patel T, DeBerardinis RJ, Wang Y, Luo W
Cellular and molecular life sciences : CMLS 2021 Jan;78(1):195-206
Cellular and molecular life sciences : CMLS 2021 Jan;78(1):195-206
miR-937-5p targets SOX17 to modulate breast cancer cell cycle and cell proliferation through the Wnt signaling pathway.
Xiong X, Xu W, Gong J, Wang L, Dai M, Chen G, Yuan L
Cellular signalling 2021 Jan;77:109818
Cellular signalling 2021 Jan;77:109818
Isoorientin exerts a urate-lowering effect through inhibition of xanthine oxidase and regulation of the TLR4-NLRP3 inflammasome signaling pathway.
An MF, Wang MY, Shen C, Sun ZR, Zhao YL, Wang XJ, Sheng J
Journal of natural medicines 2021 Jan;75(1):129-141
Journal of natural medicines 2021 Jan;75(1):129-141
Layer-specific strain for assessing the effect of naringin on systolic myocardial dysfunction induced by sepsis and its underlying mechanisms.
Sun LJ, Qiao W, Xiao YJ, Ren WD
The Journal of international medical research 2021 Jan;49(1):300060520986369
The Journal of international medical research 2021 Jan;49(1):300060520986369
Esomeprazole overcomes paclitaxel-resistance and enhances anticancer effects of paclitaxel by inducing autophagy in A549/Taxol cells.
Bai Z, Ding N, Ge J, Wang Y, Wang L, Wu N, Wei Q, Xu S, Liu X, Zhou G
Cell biology international 2021 Jan;45(1):177-187
Cell biology international 2021 Jan;45(1):177-187
Topotecan induces hepatocellular injury via ASCT2 mediated oxidative stress.
Zhou G, Qin M, Zhang X, Yang J, Yu H
Gastroenterologia y hepatologia 2021 Jan;44(1):1-12
Gastroenterologia y hepatologia 2021 Jan;44(1):1-12
Small extracellular vesicles containing miR-30a-3p attenuate the migration and invasion of hepatocellular carcinoma by targeting SNAP23 gene.
Liu C, Zhou X, Long Q, Zeng H, Sun Q, Chen Y, Wu D, Liu L
Oncogene 2021 Jan;40(2):233-245
Oncogene 2021 Jan;40(2):233-245
FBW7-NRA41-SCD1 axis synchronously regulates apoptosis and ferroptosis in pancreatic cancer cells.
Ye Z, Zhuo Q, Hu Q, Xu X, Mengqi Liu, Zhang Z, Xu W, Liu W, Fan G, Qin Y, Yu X, Ji S
Redox biology 2021 Jan;38:101807
Redox biology 2021 Jan;38:101807
Senolytic therapy ameliorates renal fibrosis postacute kidney injury by alleviating renal senescence.
Li C, Shen Y, Huang L, Liu C, Wang J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21229
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21229
Neuropathy-associated histidyl-tRNA synthetase variants attenuate protein synthesis in vitro and disrupt axon outgrowth in developing zebrafish.
Mullen P, Abbott JA, Wellman T, Aktar M, Fjeld C, Demeler B, Ebert AM, Francklyn CS
The FEBS journal 2021 Jan;288(1):142-159
The FEBS journal 2021 Jan;288(1):142-159
Arsenic exposure increased expression of HOTAIR and LincRNA-p21 in vivo and vitro.
Tan J, Sun M, Luo Q, Sun H, Wang M, Jiang C, Li S, He Y
Environmental science and pollution research international 2021 Jan;28(1):587-596
Environmental science and pollution research international 2021 Jan;28(1):587-596
CircRNA-vgll3 promotes osteogenic differentiation of adipose-derived mesenchymal stem cells via modulating miRNA-dependent integrin α5 expression.
Zhang D, Ni N, Wang Y, Tang Z, Gao H, Ju Y, Sun N, He X, Gu P, Fan X
Cell death and differentiation 2021 Jan;28(1):283-302
Cell death and differentiation 2021 Jan;28(1):283-302
SNHG1 represses the anti-cancer roles of baicalein in cervical cancer through regulating miR-3127-5p/FZD4/Wnt/β-catenin signaling.
Yu X, Xia J, Cao Y, Tang L, Tang X, Li Z
Experimental biology and medicine (Maywood, N.J.) 2021 Jan;246(1):20-30
Experimental biology and medicine (Maywood, N.J.) 2021 Jan;246(1):20-30
Endogenous promoter-driven sgRNA for monitoring the expression of low-abundance transcripts and lncRNAs.
Gao N, Hu J, He B, Ji Z, Hu X, Huang J, Wei Y, Peng J, Wei Y, Zhou Y, Shen X, Li H, Feng X, Xiao Q, Shi L, Sun Y, Zhou C, Zhou H, Yang H
Nature cell biology 2021 Jan;23(1):99-108
Nature cell biology 2021 Jan;23(1):99-108
Protection against Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice by Neferine, A Natural Product from Nelumbo nucifera Gaertn.
Min X, Guo Y, Zhou Y, Chen X
Cell journal 2021 Jan;22(4):523-531
Cell journal 2021 Jan;22(4):523-531
Quantitative proteomics reveals stage-specific protein regulation of triple negative breast cancer.
Lin Y, Lin L, Fu F, Wang C, Hu A, Xie J, Jiang M, Wang Z, Yang L, Guo R, Yang P, Shen H
Breast cancer research and treatment 2021 Jan;185(1):39-52
Breast cancer research and treatment 2021 Jan;185(1):39-52
Loss of WD2 subdomain of Apaf-1 forms an apoptosome structure which blocks activation of caspase-3 and caspase-9.
Noori AR, Tashakor A, Nikkhah M, Eriksson LA, Hosseinkhani S, Fearnhead HO
Biochimie 2021 Jan;180:23-29
Biochimie 2021 Jan;180:23-29
Characteristics of inflammation process in monocrotaline-induced pulmonary arterial hypertension in rats.
Tang C, Luo Y, Li S, Huang B, Xu S, Li L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jan;133:111081
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jan;133:111081
Neuroprotective effects of kukoamine A on 6-OHDA-induced Parkinson's model through apoptosis and iron accumulation inhibition.
Li X, Jiang XW, Chu HX, Zhao QC, Ding HW, Cai CH
Chinese herbal medicines 2021 Jan;13(1):105-115
Chinese herbal medicines 2021 Jan;13(1):105-115
Improved BMP2-CPC-stimulated osteogenesis in vitro and in vivo via modulation of macrophage polarization.
Shen H, Shi J, Zhi Y, Yang X, Yuan Y, Si J, Shen SGF
Materials science & engineering. C, Materials for biological applications 2021 Jan;118:111471
Materials science & engineering. C, Materials for biological applications 2021 Jan;118:111471
Hyperglycemia-reduced NAD(+) biosynthesis impairs corneal epithelial wound healing in diabetic mice.
Li Y, Li J, Zhao C, Yang L, Qi X, Wang X, Zhou Q, Shi W
Metabolism: clinical and experimental 2021 Jan;114:154402
Metabolism: clinical and experimental 2021 Jan;114:154402
MiR-362 suppresses cervical cancer progression via directly targeting BAP31 and activating TGFβ/Smad pathway.
Yang S, Sun Y, Jiang D, Wang J, Dang E, Li Z, Zhou J, Lu Y, Shi J, Tao L, Wang J, Jin B, Zheng L, Yang K
Cancer medicine 2021 Jan;10(1):305-316
Cancer medicine 2021 Jan;10(1):305-316
Identification of an N6-methyladenosine-mediated positive feedback loop that promotes Epstein-Barr virus infection.
Dai DL, Li X, Wang L, Xie C, Jin Y, Zeng MS, Zuo Z, Xia TL
The Journal of biological chemistry 2021 Jan-Jun;296:100547
The Journal of biological chemistry 2021 Jan-Jun;296:100547
Androgen receptor splicing variant 7 (ARV7) inhibits docetaxel sensitivity by inactivating the spindle assembly checkpoint.
Yu B, Liu Y, Luo H, Fu J, Li Y, Shao C
The Journal of biological chemistry 2021 Jan-Jun;296:100276
The Journal of biological chemistry 2021 Jan-Jun;296:100276
The ATPase ATP6V1A facilitates rabies virus replication by promoting virion uncoating and interacting with the viral matrix protein.
Liu X, Li F, Zhang J, Wang L, Wang J, Wen Z, Wang Z, Shuai L, Wang X, Ge J, Zhao D, Bu Z
The Journal of biological chemistry 2021 Jan-Jun;296:100096
The Journal of biological chemistry 2021 Jan-Jun;296:100096
Protective Effect of Retrograde Reperfusion Against Hepatic Autophagy Impairment in Rat Liver Transplantation.
Cheng Y, Lan H, Chen Y, Jiang Y, Chen Y
Transplantation proceedings 2021 Jan-Feb;53(1):443-449
Transplantation proceedings 2021 Jan-Feb;53(1):443-449
Overexpression of ICAT Inhibits the Progression of Colorectal Cancer by Binding with β-Catenin in the Cytoplasm.
Hu J, Wang Z, Chen J, Yu Z, Zhang J, Li W, Lin M, Yang X, Liu H
Technology in cancer research & treatment 2021 Jan-Dec;20:15330338211041253
Technology in cancer research & treatment 2021 Jan-Dec;20:15330338211041253
The EGFR-HSF1 axis accelerates the tumorigenesis of pancreatic cancer.
Qian W, Chen K, Qin T, Xiao Y, Li J, Yue Y, Zhou C, Ma J, Duan W, Lei J, Han L, Li L, Shen X, Wu Z, Ma Q, Wang Z
Journal of experimental & clinical cancer research : CR 2021 Jan 9;40(1):25
Journal of experimental & clinical cancer research : CR 2021 Jan 9;40(1):25
Identification of the atypical cadherin FAT1 as a novel glypican-3 interacting protein in liver cancer cells.
Meng P, Zhang YF, Zhang W, Chen X, Xu T, Hu S, Liang X, Feng M, Yang X, Ho M
Scientific reports 2021 Jan 8;11(1):40
Scientific reports 2021 Jan 8;11(1):40
Cell surface GRP78 regulates BACE2 via lysosome-dependent manner to maintain mesenchymal phenotype of glioma stem cells.
Chen Z, Wang H, Zhang Z, Xu J, Qi Y, Xue H, Gao Z, Zhao R, Wang S, Zhang S, Qiu W, Guo X, Li G
Journal of experimental & clinical cancer research : CR 2021 Jan 7;40(1):20
Journal of experimental & clinical cancer research : CR 2021 Jan 7;40(1):20
Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes.
Karki R, Sharma BR, Tuladhar S, Williams EP, Zalduondo L, Samir P, Zheng M, Sundaram B, Banoth B, Malireddi RKS, Schreiner P, Neale G, Vogel P, Webby R, Jonsson CB, Kanneganti TD
Cell 2021 Jan 7;184(1):149-168.e17
Cell 2021 Jan 7;184(1):149-168.e17
β-Conglycinin induces the formation of neutrophil extracellular traps dependent on NADPH oxidase-derived ROS, PAD4, ERK1/2 and p38 signaling pathways in mice.
Liu X, Fu Y, Wang J, Wu D, Li S, Wang C, Yang Z, Zhou E
Food & function 2021 Jan 7;12(1):154-161
Food & function 2021 Jan 7;12(1):154-161
Yangonin inhibits ethanol-induced hepatocyte senescence via miR-194/FXR axis.
Dong R, Wang X, Wang L, Wang C, Huang K, Fu T, Liu K, Wu J, Sun H, Meng Q
European journal of pharmacology 2021 Jan 5;890:173653
European journal of pharmacology 2021 Jan 5;890:173653
Progranulin induces immune escape in breast cancer via up-regulating PD-L1 expression on tumor-associated macrophages (TAMs) and promoting CD8(+) T cell exclusion.
Fang W, Zhou T, Shi H, Yao M, Zhang D, Qian H, Zeng Q, Wang Y, Jin F, Chai C, Chen T
Journal of experimental & clinical cancer research : CR 2021 Jan 4;40(1):4
Journal of experimental & clinical cancer research : CR 2021 Jan 4;40(1):4
NEO100 enables brain delivery of blood‒brain barrier impermeable therapeutics.
Wang W, Marín-Ramos NI, He H, Zeng S, Cho HY, Swenson SD, Zheng L, Epstein AL, Schönthal AH, Hofman FM, Chen L, Chen TC
Neuro-oncology 2021 Jan 30;23(1):63-75
Neuro-oncology 2021 Jan 30;23(1):63-75
Effect of Pregnane X Receptor on CYP3A29 Expression in Porcine Alveolar Macrophages during Mycoplasma hyopneumoniae Infection.
Yang X, Xing F, Wang L, Zhao W, Fu Y, Tu F, Li B, Fang X, Ren S
Animals : an open access journal from MDPI 2021 Jan 30;11(2)
Animals : an open access journal from MDPI 2021 Jan 30;11(2)
Effects of different concentrations of coated nano zinc oxide material on fecal bacterial composition and intestinal barrier in weaned piglets.
Liu H, Bai M, Xu K, Zhou J, Zhang X, Yu R, Huang R, Yin Y
Journal of the science of food and agriculture 2021 Jan 30;101(2):735-745
Journal of the science of food and agriculture 2021 Jan 30;101(2):735-745
ADAM15 Participates in Tick-Borne Encephalitis Virus Replication.
Yang Q, Pei R, Wang Y, Zhou Y, Yang M, Chen X, Chen J
Journal of virology 2021 Jan 28;95(4)
Journal of virology 2021 Jan 28;95(4)
Angiogenesis is promoted by exosomal DPP4 derived from 5-fluorouracil-resistant colon cancer cells.
Zheng X, Liu J, Li X, Tian R, Shang K, Dong X, Cao B
Cancer letters 2021 Jan 28;497:190-201
Cancer letters 2021 Jan 28;497:190-201
Absolute configuration of tetrandrine and isotetrandrine influences their anti-proliferation effects in human T cells via different regulation of NF-κB.
Xu W, Kusano J, Chen S, Yamamoto R, Matsuda H, Hara Y, Fujii Y, Hayashi S, Tanaka S, Sugiyama K, Yamada H, Hirano T
Zeitschrift fur Naturforschung. C, Journal of biosciences 2021 Jan 27;76(1-2):21-25
Zeitschrift fur Naturforschung. C, Journal of biosciences 2021 Jan 27;76(1-2):21-25
Poly(lactide-co-glycolide) Nanoparticles Mediate Sustained Gene Silencing and Improved Biocompatibility of siRNA Delivery Systems in Mouse Lungs after Pulmonary Administration.
Wu L, Wu LP, Wu J, Sun J, He Z, Rodríguez-Rodríguez C, Saatchi K, Dailey LA, Häfeli UO, Cun D, Yang M
ACS applied materials & interfaces 2021 Jan 27;13(3):3722-3737
ACS applied materials & interfaces 2021 Jan 27;13(3):3722-3737
Arsenite induce neurotoxicity of common carp: Involvement of blood brain barrier, apoptosis and autophagy, and subsequently relieved by zinc (Ⅱ) supplementation.
Wang Y, Zhao H, Liu Y, Guo M, Tian Y, Huang P, Xing M
Aquatic toxicology (Amsterdam, Netherlands) 2021 Jan 25;232:105765
Aquatic toxicology (Amsterdam, Netherlands) 2021 Jan 25;232:105765
MicroRNA-193a-5p Regulates the Synthesis of Polyunsaturated Fatty Acids by Targeting Fatty Acid Desaturase 1 (FADS1) in Bovine Mammary Epithelial Cells.
Fan Y, Arbab AAI, Zhang H, Yang Y, Lu X, Han Z, Yang Z
Biomolecules 2021 Jan 25;11(2)
Biomolecules 2021 Jan 25;11(2)
Circular RNA circRUNX1 promotes papillary thyroid cancer progression and metastasis by sponging MiR-296-3p and regulating DDHD2 expression.
Chu J, Tao L, Yao T, Chen Z, Lu X, Gao L, Fang L, Chen J, He G, Shen S, Zhang D
Cell death & disease 2021 Jan 21;12(1):112
Cell death & disease 2021 Jan 21;12(1):112
Diosmetin Ameliorates Nonalcoholic Steatohepatitis through Modulating Lipogenesis and Inflammatory Response in a STAT1/CXCL10-Dependent Manner.
Luo N, Yang C, Zhu Y, Chen Q, Zhang B
Journal of agricultural and food chemistry 2021 Jan 20;69(2):655-667
Journal of agricultural and food chemistry 2021 Jan 20;69(2):655-667
Perampanel Stimulates Mitochondrial Biogenesis in Neuronal Cells through Activation of the SIRT1/PGC-1α Signaling Pathway.
Jiang Y, Li D, Du Z, Li J, Lu R, Zhou Q, Wang Q, Zhu H
ACS chemical neuroscience 2021 Jan 20;12(2):323-329
ACS chemical neuroscience 2021 Jan 20;12(2):323-329
Downregulation of metabotropic glutamate receptor 5 alleviates central sensitization by activating autophagy via inhibiting mTOR pathway in a rat model of chronic migraine.
Niu Y, Zeng X, Qin G, Zhang D, Zhou J, Chen L
Neuroscience letters 2021 Jan 19;743:135552
Neuroscience letters 2021 Jan 19;743:135552
Mutations in GDAP1 Influence Structure and Function of the Trans-Golgi Network.
Binięda K, Rzepnikowska W, Kolakowski D, Kaminska J, Szczepankiewicz AA, Nieznańska H, Kochański A, Kabzińska D
International journal of molecular sciences 2021 Jan 18;22(2)
International journal of molecular sciences 2021 Jan 18;22(2)
Synergism of HPV and MNNG repress miR-218 promoting Het-1A cell malignant transformation by targeting GAB2.
Zhang Y, Zheng Y, Pan E, Zhao C, Zhang H, Liu R, Wang S, Pu Y, Yin L
Toxicology 2021 Jan 15;447:152635
Toxicology 2021 Jan 15;447:152635
Hypoxic conditioned promotes the proliferation of human olfactory mucosa mesenchymal stem cells and relevant lncRNA and mRNA analysis.
He J, Huang Y, Liu J, Ge L, Tang X, Lu M, Hu Z
Life sciences 2021 Jan 15;265:118861
Life sciences 2021 Jan 15;265:118861
Microcystin-leucine arginine induced the apoptosis of GnRH neurons by activating the endoplasmic reticulum stress resulting in a decrease of serum testosterone level in mice.
Jin H, Hou J, Meng X, Ma T, Wang B, Liu Z, Sha X, Ding J, Han X
Ecotoxicology and environmental safety 2021 Jan 15;208:111748
Ecotoxicology and environmental safety 2021 Jan 15;208:111748
Zinc offers splenic protection through suppressing PERK/IRE1-driven apoptosis pathway in common carp (Cyprinus carpio) under arsenic stress.
Wang Y, Zhao H, Mu M, Guo M, Xing M
Ecotoxicology and environmental safety 2021 Jan 15;208:111473
Ecotoxicology and environmental safety 2021 Jan 15;208:111473
Curcumin ameliorates mercuric chloride-induced liver injury via modulating cytochrome P450 signaling and Nrf2/HO-1 pathway.
Li S, Wang X, Xiao Y, Wang Y, Wan Y, Li X, Li Q, Tang X, Cai D, Ran B, Wu C
Ecotoxicology and environmental safety 2021 Jan 15;208:111426
Ecotoxicology and environmental safety 2021 Jan 15;208:111426
Upregulation of silent information regulator 1 alleviates mitochondrial dysfunction in the trigeminal nucleus caudalis in a rat model of chronic migraine.
Liang J, Zhou X, Wang J, Fei ZY, Qin GC, Zhang DK, Zhou JY, Chen LX
Neuroreport 2021 Jan 13;32(2):144-156
Neuroreport 2021 Jan 13;32(2):144-156
iASPP protects the heart from ischemia injury by inhibiting p53 expression and cardiomyocyte apoptosis.
Yagudin T, Zhao Y, Gao H, Zhang Y, Yang Y, Zhang X, Ma W, Daba TM, Ishmetov V, Kang K, Yang B, Pan Z
Acta biochimica et biophysica Sinica 2021 Jan 12;53(1):102-111
Acta biochimica et biophysica Sinica 2021 Jan 12;53(1):102-111
Salvia miltiorrhiza stems and leaves total phenolic acids combination with tanshinone protect against DSS-induced ulcerative colitis through inhibiting TLR4/PI3K/AKT/mTOR signaling pathway in mice.
Peng KY, Gu JF, Su SL, Zhu Y, Guo JM, Qian DW, Duan JA
Journal of ethnopharmacology 2021 Jan 10;264:113052
Journal of ethnopharmacology 2021 Jan 10;264:113052
Aptamer-based CRISPR/Cas12a assay for the ultrasensitive detection of extracellular vesicle proteins.
Li H, Xing S, Xu J, He Y, Lai Y, Wang Y, Zhang G, Guo S, Deng M, Zeng M, Liu W
Talanta 2021 Jan 1;221:121670
Talanta 2021 Jan 1;221:121670
An identified PfHMGB1 promotes microcystin-LR-induced liver injury of yellow catfish (Pelteobagrus fulvidraco).
Wang Y, Xiao X, Wang F, Yang Z, Yue J, Shi J, Ke F, Xie Z, Fan Y
Ecotoxicology and environmental safety 2021 Jan 1;207:111266
Ecotoxicology and environmental safety 2021 Jan 1;207:111266
The impact of SAMHD1 expression and mutation status in mantle cell lymphoma: An analysis of the MCL Younger and Elderly trial.
Roider T, Wang X, Hüttl K, Müller-Tidow C, Klapper W, Rosenwald A, Stewart JP, de Castro DG, Dreger P, Hermine O, Kluin-Nelemans HC, Grabe N, Dreyling M, Pott C, Ott G, Hoster E, Dietrich S
International journal of cancer 2021 Jan 1;148(1):150-160
International journal of cancer 2021 Jan 1;148(1):150-160
Role of Slit2 upregulation in recurrent miscarriage through regulation of stromal decidualization.
Chen J, Liu J, Gao S, Qiu Y, Wang Y, Zhang Y, Gao L, Qi G, Wu Y, Lash GE, Li P
Placenta 2021 Jan 1;103:1-9
Placenta 2021 Jan 1;103:1-9
mTORC1-mediated amino acid signaling is critical for cell fate determination under transplant-induced stress.
Cheng X, Ge M, Zhu S, Li D, Wang R, Xu Q, Chen Z, Xie S, Liu H
FEBS letters 2021 Feb;595(4):462-475
FEBS letters 2021 Feb;595(4):462-475
Mutation analysis of MFSD8 in an amyotrophic lateral sclerosis cohort from mainland China.
Huang L, Liu Z, Yuan Y, Shen L, Jiang H, Tang B, Wang J, Lei L
The European journal of neuroscience 2021 Feb;53(4):1197-1206
The European journal of neuroscience 2021 Feb;53(4):1197-1206
lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.
Dai W, Wang M, Wang P, Wen J, Wang J, Cha S, Xiao X, He Y, Shu R, Bai D
International journal of molecular medicine 2021 Feb;47(2):607-620
International journal of molecular medicine 2021 Feb;47(2):607-620
The miR-145-5p/CD36 pathway mediates PCB2-induced apoptosis in MCF-7 cells.
Yuan Y, Xue C, Wu Q, Wang M, Liu J, Zhang L, Xing Q, Liang J, Wu H, Chen Z
Genes & genomics 2021 Feb;43(2):161-171
Genes & genomics 2021 Feb;43(2):161-171
Hypoxia-induced PLOD1 overexpression contributes to the malignant phenotype of glioblastoma via NF-κB signaling.
Wang Z, Shi Y, Ying C, Jiang Y, Hu J
Oncogene 2021 Feb;40(8):1458-1475
Oncogene 2021 Feb;40(8):1458-1475
Activation of the G Protein-Coupled Estrogen Receptor Prevented the Development of Acute Colitis by Protecting the Crypt Cell.
Wang Q, Li Z, Liu K, Liu J, Chai S, Chen G, Wen S, Ming T, Wang J, Ma Y, Zeng H, Liu C, Xue B
The Journal of pharmacology and experimental therapeutics 2021 Feb;376(2):281-293
The Journal of pharmacology and experimental therapeutics 2021 Feb;376(2):281-293
TAR DNA-Binding Protein 43 is Cleaved by the Protease 3C of Enterovirus A71.
Wo X, Yuan Y, Xu Y, Chen Y, Wang Y, Zhao S, Lin L, Zhong X, Wang Y, Zhong Z, Zhao W
Virologica Sinica 2021 Feb;36(1):95-103
Virologica Sinica 2021 Feb;36(1):95-103
Enhancer II-targeted dsRNA decreases GDNF expression via histone H3K9 trimethylation to inhibit glioblastoma progression.
Zhang B, Han X, Gao Q, Liu J, Li S, Zha W, Wang X, Guo X, Gao D
Brain research bulletin 2021 Feb;167:22-32
Brain research bulletin 2021 Feb;167:22-32
Upregulated Nmnat2 causes neuronal death and increases seizure susceptibility in temporal lobe epilepsy.
Wu H, Meng Q, Zhang Y, Li H, Liu Y, Dong S, Liu B, Zhang H
Brain research bulletin 2021 Feb;167:1-10
Brain research bulletin 2021 Feb;167:1-10
Piezo2 channel in nodose ganglia neurons is essential in controlling hypertension in a pathway regulated directly by Nedd4-2.
Huo L, Gao Y, Zhang D, Wang S, Han Y, Men H, Yang Z, Qin X, Wang R, Kong D, Bai H, Zhang H, Zhang W, Jia Z
Pharmacological research 2021 Feb;164:105391
Pharmacological research 2021 Feb;164:105391
Effect of Babao Dan on angiogenesis of gastric cancer in vitro by regulating VEGFA/VEGFR2 signaling pathway.
Guan JH, Cao ZY, Guan B, Wei LH, Peng J, Chen YQ, Sferra TJ, Sankararaman S, Zhan ZX, Lin JM
Translational cancer research 2021 Feb;10(2):953-965
Translational cancer research 2021 Feb;10(2):953-965
Triptolide inhibits epithelial-mesenchymal transition phenotype through the p70S6k/GSK3/β-catenin signaling pathway in taxol-resistant human lung adenocarcinoma.
Tian Y, Li P, Xiao Z, Zhou J, Xue X, Jiang N, Peng C, Wu L, Tian H, Popper H, Poh ME, Marcucci F, Zhang C, Zhao X
Translational lung cancer research 2021 Feb;10(2):1007-1019
Translational lung cancer research 2021 Feb;10(2):1007-1019
Tregs facilitate obesity and insulin resistance via a Blimp-1/IL-10 axis.
Beppu LY, Mooli RGR, Qu X, Marrero GJ, Finley CA, Fooks AN, Mullen ZP, Frias AB Jr, Sipula I, Xie B, Helfrich KE, Watkins SC, Poholek AC, Ramakrishnan SK, Jurczak MJ, D'Cruz LM
JCI insight 2021 Feb 8;6(3)
JCI insight 2021 Feb 8;6(3)
NOGOB receptor-mediated RAS signaling pathway is a target for suppressing proliferating hemangioma.
Hu W, Liu Z, Salato V, North PE, Bischoff J, Kumar SN, Fang Z, Rajan S, Hussain MM, Miao QR
JCI insight 2021 Feb 8;6(3)
JCI insight 2021 Feb 8;6(3)
Fork head box M1 regulates vascular endothelial growth factor-A expression to promote the angiogenesis and tumor cell growth of gallbladder cancer.
Wang RT, Miao RC, Zhang X, Yang GH, Mu YP, Zhang ZY, Qu K, Liu C
World journal of gastroenterology 2021 Feb 28;27(8):692-707
World journal of gastroenterology 2021 Feb 28;27(8):692-707
Hypoxic pancreatic stellate cell-derived exosomal mirnas promote proliferation and invasion of pancreatic cancer through the PTEN/AKT pathway.
Cao W, Zeng Z, He Z, Lei S
Aging 2021 Feb 26;13(5):7120-7132
Aging 2021 Feb 26;13(5):7120-7132
Human drug efflux transporter ABCC5 confers acquired resistance to pemetrexed in breast cancer.
Chen J, Wang Z, Gao S, Wu K, Bai F, Zhang Q, Wang H, Ye Q, Xu F, Sun H, Lu Y, Liu Y
Cancer cell international 2021 Feb 25;21(1):136
Cancer cell international 2021 Feb 25;21(1):136
Exosomes in ovarian cancer ascites promote epithelial-mesenchymal transition of ovarian cancer cells by delivery of miR-6780b-5p.
Cai J, Gong L, Li G, Guo J, Yi X, Wang Z
Cell death & disease 2021 Feb 24;12(2):210
Cell death & disease 2021 Feb 24;12(2):210
Correction: Injectable postoperative enzyme-responsive hydrogels for reversing temozolomide resistance and reducing local recurrence after glioma operation.
Zhao Z, Shen J, Zhang L, Wang L, Xu H, Han Y, Jia J, Lu Y, Yu R, Liu H
Biomaterials science 2021 Feb 23;9(4):1466
Biomaterials science 2021 Feb 23;9(4):1466
Impaired Intestinal Akkermansia muciniphila and Aryl Hydrocarbon Receptor Ligands Contribute to Nonalcoholic Fatty Liver Disease in Mice.
Shi Z, Lei H, Chen G, Yuan P, Cao Z, Ser HL, Zhu X, Wu F, Liu C, Dong M, Song Y, Guo Y, Chen C, Hu K, Zhu Y, Zeng XA, Zhou J, Lu Y, Patterson AD, Zhang L
mSystems 2021 Feb 23;6(1)
mSystems 2021 Feb 23;6(1)
Comparison of content-toxicity-activity of six ingenane-type diterpenoids between Euphorbia kansui before and after stir-fried with vinegar by using UFLC-MS/MS, zebrafish embryos and HT-29 cells.
Zhou SK, Zhang Y, Ju YH, Zhang Q, Luo D, Cao YD, Yao WF, Tang YP, Zhang L
Journal of pharmaceutical and biomedical analysis 2021 Feb 20;195:113828
Journal of pharmaceutical and biomedical analysis 2021 Feb 20;195:113828
Small extracellular vesicle-mediated Hsp70 intercellular delivery enhances breast cancer adriamycin resistance.
Hu W, Xu Z, Zhu S, Sun W, Wang X, Tan C, Zhang Y, Zhang G, Xu Y, Tang J
Free radical biology & medicine 2021 Feb 20;164:85-95
Free radical biology & medicine 2021 Feb 20;164:85-95
Differential mitochondrial proteomic analysis of A549 cells infected with avian influenza virus subtypes H5 and H9.
Yang Y, Zhang Y, Yang C, Fang F, Wang Y, Chang H, Chen Z, Chen P
Virology journal 2021 Feb 18;18(1):39
Virology journal 2021 Feb 18;18(1):39
Polyamine Analog Diethylnorspermidine Restricts Coxsackievirus B3 and Is Overcome by 2A Protease Mutation In Vitro.
Hulsebosch BM, Mounce BC
Viruses 2021 Feb 16;13(2)
Viruses 2021 Feb 16;13(2)
Down-regulation of A(3)AR signaling by IL-6-induced GRK2 activation contributes to Th17 cell differentiation.
Hu S, Guo P, Wang Z, Zhou Z, Wang R, Zhang M, Tao J, Tai Y, Zhou W, Wei W, Wang Q
Experimental cell research 2021 Feb 15;399(2):112482
Experimental cell research 2021 Feb 15;399(2):112482
Circ_0119872 promotes uveal melanoma development by regulating the miR-622/G3BP1 axis and downstream signalling pathways.
Liu S, Chen L, Chen H, Xu K, Peng X, Zhang M
Journal of experimental & clinical cancer research : CR 2021 Feb 12;40(1):66
Journal of experimental & clinical cancer research : CR 2021 Feb 12;40(1):66
The long noncoding RNA KTN1-AS1 promotes bladder cancer tumorigenesis via KTN1 cis-activation and the consequent initiation of Rho GTPase-mediated signaling.
Hu X, Xiang L, He D, Zhu R, Fang J, Wang Z, Cao K
Clinical science (London, England : 1979) 2021 Feb 12;135(3):555-574
Clinical science (London, England : 1979) 2021 Feb 12;135(3):555-574
Protective role of serpina3c as a novel thrombin inhibitor against atherosclerosis in mice.
Qian LL, Ji JJ, Guo JQ, Wu YP, Ma GS, Yao YY
Clinical science (London, England : 1979) 2021 Feb 12;135(3):447-463
Clinical science (London, England : 1979) 2021 Feb 12;135(3):447-463
QiShenYiQi pill activates autophagy to attenuate reactive myocardial fibrosis via the PI3K/AKT/mTOR pathway.
Lv S, Yuan P, Lu C, Dong J, Li M, Qu F, Zhu Y, Zhang J
Aging 2021 Feb 11;13(4):5525-5538
Aging 2021 Feb 11;13(4):5525-5538
Diosgenin alleviates hypercholesterolemia via SRB1/CES-1/CYP7A1/FXR pathway in high-fat diet-fed rats.
Yu L, Lu H, Yang X, Li R, Shi J, Yu Y, Ma C, Sun F, Zhang S, Zhang F
Toxicology and applied pharmacology 2021 Feb 1;412:115388
Toxicology and applied pharmacology 2021 Feb 1;412:115388
A novel tonicity-responsive microRNA miR-23a-5p modulates renal cell survival under osmotic stress through targeting heat shock protein 70 HSPA1B.
Kang K, Liao X, Li Q, Chen J, Niu Y, Zeng Y, Xia S, Zeng L, Liu S, Gou D
American journal of physiology. Cell physiology 2021 Feb 1;320(2):C225-C239
American journal of physiology. Cell physiology 2021 Feb 1;320(2):C225-C239
NF-κB pathway play a role in SCD1 deficiency-induced ceramide de novo synthesis.
Zheng RH, Zhang YB, Qiu FN, Liu ZH, Han Y, Huang R, Zhao Y, Yao P, Qiu Y, Ren J
Cancer biology & therapy 2021 Feb 1;22(2):164-174
Cancer biology & therapy 2021 Feb 1;22(2):164-174
Vascular endothelial cell-secreted exosomes facilitate osteoarthritis pathogenesis by promoting chondrocyte apoptosis.
Yang RZ, Zheng HL, Xu WN, Zheng XF, Li B, Jiang LS, Jiang SD
Aging 2021 Feb 1;13(3):4647-4662
Aging 2021 Feb 1;13(3):4647-4662
Red ginseng has stronger anti-aging effects compared to ginseng possibly due to its regulation of oxidative stress and the gut microbiota.
Peng X, Hao M, Zhao Y, Cai Y, Chen X, Chen H, Zhang Y, Dong L, Liu X, Ding C, Liu W, Yang M, Luo Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Dec;93:153772
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Dec;93:153772
Gastrodin exerts protective effects in reactive TNC1 astrocytes via regulation of the Notch signaling pathway.
Zhang XLN, Yang XK, Wu CY, Yuan Y
Annals of translational medicine 2021 Dec;9(24):1754
Annals of translational medicine 2021 Dec;9(24):1754
Phosphorylated nuclear factor erythroid 2-related factor 2 promotes the secretion of C-C motif chemokine ligand 2 and the recruitment of M2 macrophages.
Huang Z, Li X, Zhou T, Jiang Y, Shi JH
Annals of translational medicine 2021 Dec;9(23):1719
Annals of translational medicine 2021 Dec;9(23):1719
IL-27 signalling promotes adipocyte thermogenesis and energy expenditure.
Wang Q, Li D, Cao G, Shi Q, Zhu J, Zhang M, Cheng H, Wen Q, Xu H, Zhu L, Zhang H, Perry RJ, Spadaro O, Yang Y, He S, Chen Y, Wang B, Li G, Liu Z, Yang C, Wu X, Zhou L, Zhou Q, Ju Z, Lu H, Xin Y, Yang X, Wang C, Liu Y, Shulman GI, Dixit VD, Lu L, Yang H, Flavell RA, Yin Z
Nature 2021 Dec;600(7888):314-318
Nature 2021 Dec;600(7888):314-318
Hypoxia-inducible factor-1α promotes proliferation of airway smooth muscle cells through miRNA-103-mediated signaling pathway under hypoxia.
Zhang C, Gao J, Zhu S
In vitro cellular & developmental biology. Animal 2021 Dec;57(10):944-952
In vitro cellular & developmental biology. Animal 2021 Dec;57(10):944-952
SIRT2 tyrosine nitration by peroxynitrite in response to renal ischemia/reperfusion injury.
Wang Y, Wu CJ, Du Y, Liu YQ, Cai JR, Wu XQ, Hu SQ
Free radical research 2021 Dec;55(11-12):1104-1118
Free radical research 2021 Dec;55(11-12):1104-1118
CoCrMo-Nanoparticles induced peri-implant osteolysis by promoting osteoblast ferroptosis via regulating Nrf2-ARE signalling pathway.
Xu Y, Sang W, Zhong Y, Xue S, Yang M, Wang C, Lu H, Huan R, Mao X, Zhu L, He C, Ma J
Cell proliferation 2021 Dec;54(12):e13142
Cell proliferation 2021 Dec;54(12):e13142
Identification of autophagic target RAB13 with small-molecule inhibitor in low-grade glioma via integrated multi-omics approaches coupled with virtual screening of traditional Chinese medicine databases.
Su W, Liao M, Tan H, Chen Y, Zhao R, Jin W, Zhu S, Zhang Y, He L, Liu B
Cell proliferation 2021 Dec;54(12):e13135
Cell proliferation 2021 Dec;54(12):e13135
Semaglutide attenuates seizure severity and ameliorates cognitive dysfunction by blocking the NLR family pyrin domain containing 3 inflammasome in pentylenetetrazole‑kindled mice.
Wang L, Ding J, Zhu C, Guo B, Yang W, He W, Li X, Wang Y, Li W, Wang F, Sun T
International journal of molecular medicine 2021 Dec;48(6)
International journal of molecular medicine 2021 Dec;48(6)
Endoplasmic reticulum stress pathway mediates T-2 toxin-induced chondrocyte apoptosis.
Liu YN, Mu YD, Wang H, Zhang M, Shi YW, Mi G, Peng LX, Chen JH
Toxicology 2021 Dec;464:152989
Toxicology 2021 Dec;464:152989
FOXO1 inhibits prostate cancer cell proliferation via suppressing E2F1 activated NPRL2 expression.
Tang Y, Jiang L, Zhao X, Hu D, Zhao G, Luo S, Du X, Tang W
Cell biology international 2021 Dec;45(12):2510-2520
Cell biology international 2021 Dec;45(12):2510-2520
3-Hydroxybenzaldehyde and 4-Hydroxybenzaldehyde enhance survival of mouse astrocytes treated with Angiostrongylus cantonensis young adults excretory/secretory products.
Chen KY, Chen YJ, Cheng CJ, Jhan KY, Chiu CH, Wang LC
Biomedical journal 2021 Dec;44(6 Suppl 2):S258-S266
Biomedical journal 2021 Dec;44(6 Suppl 2):S258-S266
GLO 1 and PKCλ Regulate ALDH1-positive Breast Cancer Stem Cell Survival.
Motomura H, Tamori S, Yatani MA, Namiki A, Onaga C, Ozaki A, Takasawa R, Mano Y, Sato T, Hara Y, Sato K, Xiong Y, Harada Y, Hanawa T, Tanuma SI, Sasaki K, Ohno S, Akimoto K
Anticancer research 2021 Dec;41(12):5959-5971
Anticancer research 2021 Dec;41(12):5959-5971
The transcribed ultraconserved element uc.51 promotes the proliferation and metastasis of breast cancer by stabilizing NONO.
Shi X, Huang X, Chen R, Li Y, Xu Y, Zhang W, Zhu Q, Zha X, Wang J
Clinical & experimental metastasis 2021 Dec;38(6):551-571
Clinical & experimental metastasis 2021 Dec;38(6):551-571
ubtor Mutation Causes Motor Hyperactivity by Activating mTOR Signaling in Zebrafish.
Wang T, Zhou M, Zhang Q, Zhang C, Peng G
Neuroscience bulletin 2021 Dec;37(12):1658-1670
Neuroscience bulletin 2021 Dec;37(12):1658-1670
Stigmasterol inhibits the progression of lung cancer by regulating retinoic acid-related orphan receptor C.
Dong Y, Chen C, Chen C, Zhang C, Zhang L, Zhang Y, Li Y, Dong Z
Histology and histopathology 2021 Dec;36(12):1285-1299
Histology and histopathology 2021 Dec;36(12):1285-1299
The flavonoid procyanidin C1 has senotherapeutic activity and increases lifespan in mice.
Xu Q, Fu Q, Li Z, Liu H, Wang Y, Lin X, He R, Zhang X, Ju Z, Campisi J, Kirkland JL, Sun Y
Nature metabolism 2021 Dec;3(12):1706-1726
Nature metabolism 2021 Dec;3(12):1706-1726
Caspase-6 promotes activation of the caspase-11-NLRP3 inflammasome during gram-negative bacterial infections.
Zheng M, Karki R, Kancharana B, Berns H, Pruett-Miller SM, Kanneganti TD
The Journal of biological chemistry 2021 Dec;297(6):101379
The Journal of biological chemistry 2021 Dec;297(6):101379
MEHP induces pyroptosis and autophagy alternation by cathepsin B activation in INS-1 cells.
Jiang L, Qiu T, Yao X, Chen H, Yao K, Sun X, Yang G, Jiang L, Zhang C, Wang N, Zhang H, Liu X
Environmental science and pollution research international 2021 Dec;28(47):66628-66642
Environmental science and pollution research international 2021 Dec;28(47):66628-66642
A bivalent cyclic RGD-siRNA conjugate enhances the antitumor effect of apatinib via co-inhibiting VEGFR2 in non-small cell lung cancer xenografts.
Liao L, Cen B, Li G, Wei Y, Wang Z, Huang W, He S, Yuan Y, Ji A
Drug delivery 2021 Dec;28(1):1432-1442
Drug delivery 2021 Dec;28(1):1432-1442
Exosomal ANXA2 derived from ovarian cancer cells regulates epithelial-mesenchymal plasticity of human peritoneal mesothelial cells.
Gao L, Nie X, Gou R, Hu Y, Dong H, Li X, Lin B
Journal of cellular and molecular medicine 2021 Dec;25(23):10916-10929
Journal of cellular and molecular medicine 2021 Dec;25(23):10916-10929
FPR2 serves a role in recurrent spontaneous abortion by regulating trophoblast function via the PI3K/AKT signaling pathway.
Li A, Li S, Zhang C, Fang Z, Sun Y, Peng Y, Wang X, Zhang M
Molecular medicine reports 2021 Dec;24(6)
Molecular medicine reports 2021 Dec;24(6)
Knockdown of TRIM9 attenuates irinotecan‑induced intestinal mucositis in IEC‑6 cells by regulating DUSP6 expression via the P38 pathway.
Zhao W, Wang Q
Molecular medicine reports 2021 Dec;24(6)
Molecular medicine reports 2021 Dec;24(6)
Suppression of ER-stress induction of GRP78 as an anti-neoplastic mechanism of the cardiac glycoside Lanatoside C in pancreatic cancer: Lanatoside C suppresses GRP78 stress induction.
Ha DP, Tsai YL, Lee AS
Neoplasia (New York, N.Y.) 2021 Dec;23(12):1213-1226
Neoplasia (New York, N.Y.) 2021 Dec;23(12):1213-1226
Danshensu derivative ADTM ameliorates CCl(4)‑induced acute liver injury in mice through inhibiting oxidative stress and apoptosis.
Jia S, Chen Q, Wu J, Yao X, Shao J, Cheng X, Zhang C, Cen D, Wang Y, Shen Z, Shan L, Yao X
Pathology, research and practice 2021 Dec;228:153656
Pathology, research and practice 2021 Dec;228:153656
Mel1b and Mel1c melatonin receptors mediate green light-induced secretion of growth hormone in chick adenohypophysis cells via the AC/PKA and ERK1/2 signalling pathways.
Liu X, Wang L, Wang Z, Dong Y, Chen Y, Cao J
Journal of photochemistry and photobiology. B, Biology 2021 Dec;225:112322
Journal of photochemistry and photobiology. B, Biology 2021 Dec;225:112322
Arsenic (III) induces oxidative stress and inflammation in the gills of common carp, which is ameliorated by zinc (II).
Lu H, Zhao H, Wang Y, Guo M, Mu M, Liu Y, Nie X, Huang P, Xing M
Journal of inorganic biochemistry 2021 Dec;225:111617
Journal of inorganic biochemistry 2021 Dec;225:111617
Knockdown of METTL14 suppresses the malignant progression of non-small cell lung cancer by reducing Twist expression.
Yang F, Yuan WQ, Li J, Luo YQ
Oncology letters 2021 Dec;22(6):847
Oncology letters 2021 Dec;22(6):847
CMPK2 accelerates liver ischemia/reperfusion injury via the NLRP3 signaling pathway.
Luo Y, Zheng D, Mou T, Pu J, Huang Z, Chen W, Zhang Y, Wu Z
Experimental and therapeutic medicine 2021 Dec;22(6):1358
Experimental and therapeutic medicine 2021 Dec;22(6):1358
Hsa-miR-335 enhances cell migration and invasion in lung adenocarcinoma through targeting Copine-1.
Wang Y, Zhang J, Zhong LY, Huang SJ, Yu NN, Ouyang L, Niu YL, Chen JX, Lu CH, He QY
MedComm 2021 Dec;2(4):810-820
MedComm 2021 Dec;2(4):810-820
Antidepressant effect of catalpol on corticosterone-induced depressive-like behavior involves the inhibition of HPA axis hyperactivity, central inflammation and oxidative damage probably via dual regulation of NF-κB and Nrf2.
Song L, Wu X, Wang J, Guan Y, Zhang Y, Gong M, Wang Y, Li B
Brain research bulletin 2021 Dec;177:81-91
Brain research bulletin 2021 Dec;177:81-91
Small molecule targeting topoisomerase 3β for cancer therapy.
Zhang X, Wang L, Zhang Q, Lyu S, Zhu D, Shen M, Ke X, Qu Y
Pharmacological research 2021 Dec;174:105927
Pharmacological research 2021 Dec;174:105927
Dihydroartemisinin ameliorates retinal vascular dysfunction in diabetes mellitus via the FASN/Kmal-mTOR/SREBP1 feedback loop.
Gu C, She X, Zhou C, Su T, He S, Meng C, Gu Q, Luo D, Zheng Z, Qiu Q
Pharmacological research 2021 Dec;174:105871
Pharmacological research 2021 Dec;174:105871
Viral RNA N6-methyladenosine modification modulates both innate and adaptive immune responses of human respiratory syncytial virus.
Xue M, Zhang Y, Wang H, Kairis EL, Lu M, Ahmad S, Attia Z, Harder O, Zhang Z, Wei J, Chen P, Gao Y, Peeples ME, Sharma A, Boyaka P, He C, Hur S, Niewiesk S, Li J
PLoS pathogens 2021 Dec;17(12):e1010142
PLoS pathogens 2021 Dec;17(12):e1010142
DNA damage-inducible transcript 3 restrains osteoclast differentiation and function.
Yang B, Sun H, Jia M, He Y, Luo Y, Wang T, Wu Y, Wang J
Bone 2021 Dec;153:116162
Bone 2021 Dec;153:116162
Acupuncture regulates the autophagy of ovarian granulosa cells in polycystic ovarian syndrome ovulation disorder by inhibiting the PI3K/AKT/mTOR pathway through LncMEG3.
Chen X, Tang H, Liang Y, Wu P, Xie L, Ding Y, Yang P, Long B, Lin J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112288
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112288
Selenoprotein S attenuates high glucose and/or ox-LDL-induced endothelium injury by regulating Akt/mTOR signaling and autophagy.
Wang Z, Li Y, Yao J, Yu S, Yu H, Men L, Du J
The international journal of biochemistry & cell biology 2021 Dec;141:106111
The international journal of biochemistry & cell biology 2021 Dec;141:106111
Shockwave Treatment Enhanced Extracellular Matrix Production in Articular Chondrocytes Through Activation of the ROS/MAPK/Nrf2 Signaling Pathway.
Shen PC, Chou SH, Lu CC, Huang HT, Chien SH, Huang PJ, Liu ZM, Shih CL, Su SJ, Chen LM, Tien YC
Cartilage 2021 Dec;13(2_suppl):238S-253S
Cartilage 2021 Dec;13(2_suppl):238S-253S
Silencing FYVE, RhoGEF, and PH domain containing 1 (FGD1) suppresses melanoma progression by inhibiting PI3K/AKT signaling pathway.
Niu Z, Li Y, Xu Y, Jiang W, Tao R, Chen Y, Han Y
Bioengineered 2021 Dec;12(2):12193-12205
Bioengineered 2021 Dec;12(2):12193-12205
Role of Rho guanine nucleotide exchange factors in non-small cell lung cancer.
Zeng RJ, Xie WJ, Zheng CW, Chen WX, Wang SM, Li Z, Cheng CB, Zou HY, Xu LY, Li EM
Bioengineered 2021 Dec;12(2):11169-11187
Bioengineered 2021 Dec;12(2):11169-11187
Mechanistic insights into the renoprotective role of curcumin in cisplatin-induced acute kidney injury: network pharmacology analysis and experimental validation.
Hui Z, Dong QQ, Shu HP, Tu YC, Liao QQ, Yao LJ
Bioengineered 2021 Dec;12(2):11041-11056
Bioengineered 2021 Dec;12(2):11041-11056
Human umbilical vein endothelial cells derived-exosomes promote osteosarcoma cell stemness by activating Notch signaling pathway.
Yang J, Hu Y, Wang L, Sun X, Yu L, Guo W
Bioengineered 2021 Dec;12(2):11007-11017
Bioengineered 2021 Dec;12(2):11007-11017
A comprehensive genome-wide analysis of long non-coding RNA and mRNA expression profiles of JAK2V617F-positive classical myeloproliferative neoplasms.
Zhou J, Wu H, Guo C, Li B, Zhou LL, Liang AB, Fu JF
Bioengineered 2021 Dec;12(2):10564-10586
Bioengineered 2021 Dec;12(2):10564-10586
Transcription factor 3 (TCF3) combined with histone deacetylase 3 (HDAC3) down-regulates microRNA-101 to promote Burkitt lymphoma cell proliferation and inhibit apoptosis.
Dong L, Huang J, Zu P, Liu J, Gao X, Du J, Li Y
Bioengineered 2021 Dec;12(1):7995-8005
Bioengineered 2021 Dec;12(1):7995-8005
Fat mass and obesity-associated protein (FTO) mediates signal transducer and activator of transcription 3 (STAT3)-drived resistance of breast cancer to doxorubicin.
Wang Y, Cheng Z, Xu J, Lai M, Liu L, Zuo M, Dang L
Bioengineered 2021 Dec;12(1):1874-1889
Bioengineered 2021 Dec;12(1):1874-1889
MicroRNA miR-188-5p as a mediator of long non-coding RNA MALAT1 regulates cell proliferation and apoptosis in multiple myeloma.
Liu H, Chi Z, Jin H, Yang W
Bioengineered 2021 Dec;12(1):1611-1626
Bioengineered 2021 Dec;12(1):1611-1626
A virulent Bacillus cereus strain from deep-sea cold seep induces pyroptosis in a manner that involves NLRP3 inflammasome, JNK pathway, and lysosomal rupture.
Zhao Y, Jiang S, Zhang J, Guan XL, Sun BG, Sun L
Virulence 2021 Dec;12(1):1362-1376
Virulence 2021 Dec;12(1):1362-1376
ATR kinase activity promotes antibody class switch recombination in B cells through cell cycle regulation without suppressing DSB resection and microhomology usage.
Sun X, Liu M, Bai J, Xu J, Zhu C, Dong J, Chen C
Journal of leukocyte biology 2021 Dec;110(6):1101-1112
Journal of leukocyte biology 2021 Dec;110(6):1101-1112
A living cell-based fluorescent reporter for high-throughput screening of anti-tumor drugs.
Tang N, Li L, Xie F, Lu Y, Zuo Z, Shan H, Zhang Q, Zhang L
Journal of pharmaceutical analysis 2021 Dec;11(6):808-814
Journal of pharmaceutical analysis 2021 Dec;11(6):808-814
GABA(A) receptor agonist muscimol rescues inhibitory microcircuit defects in the olfactory bulb and improves olfactory function in APP/PS1 transgenic mice.
Hu B, Geng C, Guo F, Liu Y, Zong YC, Hou XY
Neurobiology of aging 2021 Dec;108:47-57
Neurobiology of aging 2021 Dec;108:47-57
1β-Hydroxyalantolactone from Inulae Flos alleviated the progression of pulmonary fibrosis via inhibiting JNK/FOXO1/NF-κB pathway.
Yu B, Jin XQ, Yu WY, Dong YY, Ying HZ, Yu CH
International immunopharmacology 2021 Dec;101(Pt A):108339
International immunopharmacology 2021 Dec;101(Pt A):108339
Dietary hawthorn-leaves flavonoids improves ovarian function and liver lipid metabolism in aged breeder hens.
Dai H, Lv Z, Huang Z, Ye N, Li S, Jiang J, Cheng Y, Shi F
Poultry science 2021 Dec;100(12):101499
Poultry science 2021 Dec;100(12):101499
Mannan-binding lectin deficiency augments hepatic endoplasmic reticulum stress through IP3R-controlled calcium release.
Chen Y, Hu M, Deng F, Wang P, Lin J, Zheng Z, Liu Y, Dong L, Lu X, Chen Z, Zhou J, Zuo D
Cell calcium 2021 Dec;100:102477
Cell calcium 2021 Dec;100:102477
Transcriptomic-based toxicological investigations of graphene oxide with modest cytotoxicity to human umbilical vein endothelial cells: changes of Toll-like receptor signaling pathways.
Luo Y, Wang X, Cao Y
Toxicology research 2021 Dec;10(6):1104-1115
Toxicology research 2021 Dec;10(6):1104-1115
Acquiring high expression of suilysin enable non-epidemic Streptococccus suis to cause streptococcal toxic shock-like syndrome (STSLS) through NLRP3 inflammasome hyperactivation.
Xu L, Lin L, Lu X, Xiao P, Liu R, Wu M, Jin M, Zhang A
Emerging microbes & infections 2021 Dec;10(1):1309-1319
Emerging microbes & infections 2021 Dec;10(1):1309-1319
The Mechanism of Mitochondrial Injury in Alpha-1 Antitrypsin Deficiency Mediated Liver Disease.
Khodayari N, Wang RL, Oshins R, Lu Y, Millett M, Aranyos AM, Mostofizadeh S, Scindia Y, Flagg TO, Brantly M
International journal of molecular sciences 2021 Dec 9;22(24)
International journal of molecular sciences 2021 Dec 9;22(24)
SARS-CoV-2 ORF3a Induces Incomplete Autophagy via the Unfolded Protein Response.
Su WQ, Yu XJ, Zhou CM
Viruses 2021 Dec 9;13(12)
Viruses 2021 Dec 9;13(12)
MiRNA-132/212 regulates tight junction stabilization in blood-brain barrier after stroke.
Yan H, Kanki H, Matsumura S, Kawano T, Nishiyama K, Sugiyama S, Takemori H, Mochizuki H, Sasaki T
Cell death discovery 2021 Dec 8;7(1):380
Cell death discovery 2021 Dec 8;7(1):380
NLRP3 inflammasome signal pathway involves in Vibrio harveyi-induced inflammatory response in murine peritoneal macrophages in vitro.
Yu G, Wang J, Zhang W, Yang Q, Liu G, Wang L, Bello BK, Zhang X, Zhang T, Fan H, Zhao P, Liang W, Dong J
Acta biochimica et biophysica Sinica 2021 Dec 8;53(12):1590-1601
Acta biochimica et biophysica Sinica 2021 Dec 8;53(12):1590-1601
HOPX Plays a Critical Role in Antiretroviral Drugs Induced Epigenetic Modification and Cardiac Hypertrophy.
Kashyap S, Rabbani M, de Lima I, Kondrachuk O, Patel R, Shafiei MS, Mukker A, Rajakumar A, Gupta MK
Cells 2021 Dec 8;10(12)
Cells 2021 Dec 8;10(12)
ZNF382 controls mouse neuropathic pain via silencer-based epigenetic inhibition of Cxcl13 in DRG neurons.
Ma L, Yu L, Jiang BC, Wang J, Guo X, Huang Y, Ren J, Sun N, Gao DS, Ding H, Lu J, Zhou H, Zou L, Gao Y, Wang L, Sun K, Ming Y, Meng Z, Tao YX, Yan M
The Journal of experimental medicine 2021 Dec 6;218(12)
The Journal of experimental medicine 2021 Dec 6;218(12)
Biophysical and biochemical properties of PHGDH revealed by studies on PHGDH inhibitors.
Tan Y, Zhou X, Gong Y, Gou K, Luo Y, Jia D, Dai L, Zhao Y, Sun Q
Cellular and molecular life sciences : CMLS 2021 Dec 31;79(1):27
Cellular and molecular life sciences : CMLS 2021 Dec 31;79(1):27
Diacerein attenuates vascular dysfunction by reducing inflammatory response and insulin resistance in type 2 diabetic rats.
He A, Shen J, Xue Y, Xiang Li, Li Y, Huang L, Lv D, Luo M
Biochemical and biophysical research communications 2021 Dec 31;585:68-74
Biochemical and biophysical research communications 2021 Dec 31;585:68-74
Irisin Association with Ki-67, MCM3 and MT-I/II in Squamous Cell Carcinomas of the Larynx.
Pinkowska A, Nowinska K, Ciesielska U, Podhorska-Okolow M
Biomolecules 2021 Dec 30;12(1)
Biomolecules 2021 Dec 30;12(1)
CD38 activation by monosodium urate crystals contributes to inflammatory responses in human and murine macrophages.
Wen S, Arakawa H, Tamai I
Biochemical and biophysical research communications 2021 Dec 3;581:6-11
Biochemical and biophysical research communications 2021 Dec 3;581:6-11
USP30-AS1 contributes to mitochondrial quality control in glioblastoma cells.
Wang N, Li J, Xin Q, Xu N
Biochemical and biophysical research communications 2021 Dec 3;581:31-37
Biochemical and biophysical research communications 2021 Dec 3;581:31-37
Loss of ATF4 leads to functional aging-like attrition of adult hematopoietic stem cells.
Sun Y, Lin X, Liu B, Zhang Y, Li W, Zhang S, He F, Tian H, Zhu X, Liu X, Wu J, Cai J, Li M
Science advances 2021 Dec 24;7(52):eabj6877
Science advances 2021 Dec 24;7(52):eabj6877
Antiplatelet and Antithrombotic Effects of Isaridin E Isolated from the Marine-Derived Fungus via Downregulating the PI3K/Akt Signaling Pathway.
Pan N, Li ZC, Li ZH, Chen SH, Jiang MH, Yang HY, Liu YS, Hu R, Zeng YW, Dai LH, Liu L, Wang GL
Marine drugs 2021 Dec 24;20(1)
Marine drugs 2021 Dec 24;20(1)
Installation of Pargyline, a LSD1 Inhibitor, in the HDAC Inhibitory Template Culminated in the Identification of a Tractable Antiprostate Cancer Agent.
Ojha R, Chen IC, Hsieh CM, Nepali K, Lai RW, Hsu KC, Lin TE, Pan SL, Chen MC, Liou JP
Journal of medicinal chemistry 2021 Dec 23;64(24):17824-17845
Journal of medicinal chemistry 2021 Dec 23;64(24):17824-17845
Heat stress affects fetal brain and intestinal function associated with the alterations of placental barrier in late pregnant mouse.
Guo H, Yang Y, Qiao Y, He J, Yao W, Zheng W
Ecotoxicology and environmental safety 2021 Dec 20;227:112916
Ecotoxicology and environmental safety 2021 Dec 20;227:112916
Interleukin-37 inhibits inflammation activation and disease severity of PM2.5-induced airway hyperresponsiveness.
Wang M, Hou S, Lu X, Li J, Li R, Yan X
Ecotoxicology and environmental safety 2021 Dec 20;227:112890
Ecotoxicology and environmental safety 2021 Dec 20;227:112890
Cancer-associated fibroblasts promote oral squamous cell carcinoma progression through LOX-mediated matrix stiffness.
Zhang JY, Zhu WW, Wang MY, Zhai RD, Wang Q, Shen WL, Liu LK
Journal of translational medicine 2021 Dec 20;19(1):513
Journal of translational medicine 2021 Dec 20;19(1):513
Nuclear factor I-C disrupts cellular homeostasis between autophagy and apoptosis via miR-200b-Ambra1 in neural tube defects.
Huang W, Huang T, Liu Y, Fu J, Wei X, Liu D, Ma W, Gu H, Yuan Z
Cell death & disease 2021 Dec 20;13(1):17
Cell death & disease 2021 Dec 20;13(1):17
p66α Suppresses Breast Cancer Cell Growth and Migration by Acting as Co-Activator of p53.
Zhang Q, Zhang Y, Zhang J, Zhang D, Li M, Yan H, Zhang H, Song L, Wang J, Hou Z, Yang Y, Zou X
Cells 2021 Dec 20;10(12)
Cells 2021 Dec 20;10(12)
Nucleosomes enter cells by clathrin- and caveolin-dependent endocytosis.
Wang H, Shan X, Ren M, Shang M, Zhou C
Nucleic acids research 2021 Dec 2;49(21):12306-12319
Nucleic acids research 2021 Dec 2;49(21):12306-12319
Evaluating the Effect of Lenvatinib on Sorafenib-Resistant Hepatocellular Carcinoma Cells.
Shi T, Iwama H, Fujita K, Kobara H, Nishiyama N, Fujihara S, Goda Y, Yoneyama H, Morishita A, Tani J, Yamada M, Nakahara M, Takuma K, Masaki T
International journal of molecular sciences 2021 Dec 2;22(23)
International journal of molecular sciences 2021 Dec 2;22(23)
A distributed residue network permits conformational binding specificity in a conserved family of actin remodelers.
Hwang T, Parker SS, Hill SM, Ilunga MW, Grant RA, Mouneimne G, Keating AE
eLife 2021 Dec 2;10
eLife 2021 Dec 2;10
MIF promotes neurodegeneration and cell death via its nuclease activity following traumatic brain injury.
Ruan Z, Lu Q, Wang JE, Zhou M, Liu S, Zhang H, Durvasula A, Wang Y, Wang Y, Luo W, Wang Y
Cellular and molecular life sciences : CMLS 2021 Dec 18;79(1):39
Cellular and molecular life sciences : CMLS 2021 Dec 18;79(1):39
TCF4 and HuR mediated-METTL14 suppresses dissemination of colorectal cancer via N6-methyladenosine-dependent silencing of ARRDC4.
Wang H, Wei W, Zhang ZY, Liu Y, Shi B, Zhong W, Zhang HS, Fang X, Sun CL, Wang JB, Liu LX
Cell death & disease 2021 Dec 17;13(1):3
Cell death & disease 2021 Dec 17;13(1):3
Probiotic Bacillus cereus Alleviates Dextran Sulfate Sodium-Induced Colitis in Mice through Improvement of the Intestinal Barrier Function, Anti-Inflammation, and Gut Microbiota Modulation.
Sheng K, Xu Y, Kong X, Wang J, Zha X, Wang Y
Journal of agricultural and food chemistry 2021 Dec 15;69(49):14810-14823
Journal of agricultural and food chemistry 2021 Dec 15;69(49):14810-14823
Tangeretin maintains antioxidant activity by reducing CUL3 mediated NRF2 ubiquitination.
Wang Y, Jin R, Chen J, Cao J, Xiao J, Li X, Sun C
Food chemistry 2021 Dec 15;365:130470
Food chemistry 2021 Dec 15;365:130470
ERα promotes transcription of tumor suppressor gene ApoA-I by establishing H3K27ac-enriched chromatin microenvironment in breast cancer cells.
Wang B, Shen Y, Liu T, Tan L
Journal of Zhejiang University. Science. B 2021 Dec 15;22(12):1034-1044
Journal of Zhejiang University. Science. B 2021 Dec 15;22(12):1034-1044
The laminin-binding integrins regulate nuclear factor κB-dependent epithelial cell polarity and inflammation.
Yazlovitskaya EM, Plosa E, Bock F, Viquez OM, Mernaugh G, Gewin LS, De Arcangelis A, Georges-Labouesse E, Sonnenberg A, Blackwell TS, Pozzi A, Zent R
Journal of cell science 2021 Dec 15;134(24)
Journal of cell science 2021 Dec 15;134(24)
Suppressing Alpha-Hemolysin as Potential Target to Screen of Flavonoids to Combat Bacterial Coinfection.
He S, Deng Q, Liang B, Yu F, Yu X, Guo D, Liu X, Dong H
Molecules (Basel, Switzerland) 2021 Dec 14;26(24)
Molecules (Basel, Switzerland) 2021 Dec 14;26(24)
TRPV1 channel mediates NLRP3 inflammasome-dependent neuroinflammation in microglia.
Zhang Y, Hou B, Liang P, Lu X, Wu Y, Zhang X, Fan Y, Liu Y, Chen T, Liu W, Peng B, Yin J, Han S, He X
Cell death & disease 2021 Dec 14;12(12):1159
Cell death & disease 2021 Dec 14;12(12):1159
α-Synuclein aggregation in the olfactory bulb induces olfactory deficits by perturbing granule cells and granular-mitral synaptic transmission.
Chen F, Liu W, Liu P, Wang Z, Zhou Y, Liu X, Li A
NPJ Parkinson's disease 2021 Dec 13;7(1):114
NPJ Parkinson's disease 2021 Dec 13;7(1):114
Polysaccharide CM1 from Cordyceps militaris hinders adipocyte differentiation and alleviates hyperlipidemia in LDLR((+/-)) hamsters.
Yu WQ, Yin F, Shen N, Lin P, Xia B, Li YJ, Guo SD
Lipids in health and disease 2021 Dec 13;20(1):178
Lipids in health and disease 2021 Dec 13;20(1):178
Carnosol alleviates nonalcoholic fatty liver disease by inhibiting mitochondrial dysfunction and apoptosis through targeting of PRDX3.
Geng Y, Wang Y, Sun R, Kang X, Zhao H, Zhu M, Sun Y, Hu Y, Wang Z, Tian X, Zhao Y, Yao J
Toxicology and applied pharmacology 2021 Dec 1;432:115758
Toxicology and applied pharmacology 2021 Dec 1;432:115758
Involvement of endoplasmic reticulum stress-activated PERK-eIF2α-ATF4 signaling pathway in T-2 toxin-induced apoptosis of porcine renal epithelial cells.
Liu X, Wang Z, Wang X, Yan X, He Q, Liu S, Ye M, Li X, Yuan Z, Wu J, Yi J, Wen L, Li R
Toxicology and applied pharmacology 2021 Dec 1;432:115753
Toxicology and applied pharmacology 2021 Dec 1;432:115753
PAX5-activated lncRNA ARRDC1-AS1 accelerates the autophagy and progression of DLBCL through sponging miR-2355-5p to regulate ATG5.
Xu H, Yu X, Yang Z, Song Q, Cheng S, He Z, Dai L
Life sciences 2021 Dec 1;286:119932
Life sciences 2021 Dec 1;286:119932
Ketamine enhances novel object recognition memory reconsolidation via the BDNF/TrkB pathway in mice.
Fan JF, Tang ZH, Wang SY, Lei S, Zhang B, Tian SW
Physiology & behavior 2021 Dec 1;242:113626
Physiology & behavior 2021 Dec 1;242:113626
Role of the hippo signaling pathway in the extracellular matrix degradation of chondrocytes induced by fluoride exposure.
Yu FF, Zuo J, Fu X, Gao MH, Sun L, Yu SY, Li Z, Zhou GY, Ba Y
Ecotoxicology and environmental safety 2021 Dec 1;225:112796
Ecotoxicology and environmental safety 2021 Dec 1;225:112796
Cypermethrin triggers YY1-mediated testosterone biosynthesis suppression.
Liu C, Qu J, Wu M, Huang X, Li L
Ecotoxicology and environmental safety 2021 Dec 1;225:112792
Ecotoxicology and environmental safety 2021 Dec 1;225:112792
Quercetin reverses chronic unpredictable mild stress-induced depression-like behavior in vivo by involving nuclear factor-E2-related factor 2.
Guan Y, Wang J, Wu X, Song L, Wang Y, Gong M, Li B
Brain research 2021 Dec 1;1772:147661
Brain research 2021 Dec 1;1772:147661
Metformin alleviates hydrogen peroxide-induced inflammation and oxidative stress via inhibiting P2X7R signaling in spinal cord tissue cells neurons.
Wang G, Chen S, Shao Z, Li Y, Wang W, Mao L, Li J, Mei X
Canadian journal of physiology and pharmacology 2021 Aug;99(8):768-774
Canadian journal of physiology and pharmacology 2021 Aug;99(8):768-774
AKR1C3 decreased CML sensitivity to Imatinib in bone marrow microenvironment via dysregulation of miR-379-5p.
Pan D, Yang W, Zeng Y, Li W, Wang K, Zhao L, Li J, Ye Y, Guo Q
Cellular signalling 2021 Aug;84:110038
Cellular signalling 2021 Aug;84:110038
Heat shock protein 90 inhibitor ameliorates pancreatic fibrosis by degradation of transforming growth factor-β receptor.
Peng YF, Lin H, Liu DC, Zhu XY, Huang N, Wei YX, Li L
Cellular signalling 2021 Aug;84:110001
Cellular signalling 2021 Aug;84:110001
Microglial Calhm2 regulates neuroinflammation and contributes to Alzheimer's disease pathology.
Cheng J, Dong Y, Ma J, Pan R, Liao Y, Kong X, Li X, Li S, Chen P, Wang L, Yu Y, Yuan Z
Science advances 2021 Aug;7(35)
Science advances 2021 Aug;7(35)
Rapid generation of maternal mutants via oocyte transgenic expression of CRISPR-Cas9 and sgRNAs in zebrafish.
Zhang C, Lu T, Zhang Y, Li J, Tarique I, Wen F, Chen A, Wang J, Zhang Z, Zhang Y, Shi DL, Shao M
Science advances 2021 Aug;7(32)
Science advances 2021 Aug;7(32)
The intervention of intestinal Wnt/β-catenin pathway alters inflammation and disease severity of CIA.
Tan W, Qiu Y, Chen N, Gao J, Liang J, Liu Y, Zhao D
Immunologic research 2021 Aug;69(4):323-333
Immunologic research 2021 Aug;69(4):323-333
Milk Polar Lipids Supplementation to Obese Rats During Pregnancy and Lactation Benefited Skeletal Outcomes of Male Offspring.
Han L, Du M, Ren F, Mao X
Molecular nutrition & food research 2021 Aug;65(15):e2001208
Molecular nutrition & food research 2021 Aug;65(15):e2001208
H. pylori infection induces CXCL8 expression and promotes gastric cancer progress through downregulating KLF4.
Liu Z, Wu X, Tian Y, Zhang W, Qiao S, Xu W, Liu Y, Wang S
Molecular carcinogenesis 2021 Aug;60(8):524-537
Molecular carcinogenesis 2021 Aug;60(8):524-537
Exosomal miR-193b-5p as a regulator of LPS-induced inflammation in dairy cow mammary epithelial cells.
Xu H, Zhang T, Hu X, Xie Y, Wu R, Lian S, Wang J
In vitro cellular & developmental biology. Animal 2021 Aug;57(7):695-703
In vitro cellular & developmental biology. Animal 2021 Aug;57(7):695-703
Circadian misalignment promotes vascular smooth muscle cell apoptosis via defective autophagy.
Guo Z, Yu B, Li X, Yang X, Wang C, Fan L
Journal of molecular histology 2021 Aug;52(4):799-808
Journal of molecular histology 2021 Aug;52(4):799-808
Progranulin promotes osteogenic differentiation of periodontal membrane stem cells in both inflammatory and non-inflammatory conditions.
Yu M, Sun L, Ba P, Li L, Chen J, Sun Q
The Journal of international medical research 2021 Aug;49(8):3000605211032508
The Journal of international medical research 2021 Aug;49(8):3000605211032508
Lipocalin-2: a role in hepatic gluconeogenesis via AMP-activated protein kinase (AMPK).
Sun WX, Lou K, Chen LJ, Liu SD, Pang SG
Journal of endocrinological investigation 2021 Aug;44(8):1753-1765
Journal of endocrinological investigation 2021 Aug;44(8):1753-1765
Hepatoprotective effects of loach (Misgurnus anguillicaudatus) lyophilized powder on dimethylnitrosamine-induced liver fibrosis in rats.
Zhang Q, Shang MM, Ling QF, Wu XP, Liu CY
Archives of pharmacal research 2021 Aug;44(8):1-12
Archives of pharmacal research 2021 Aug;44(8):1-12
Chicoric acid attenuates hyperglycemia-induced endothelial dysfunction through AMPK-dependent inhibition of oxidative/nitrative stresses.
Ma X, Zhang J, Wu Z, Wang X
Journal of receptor and signal transduction research 2021 Aug;41(4):378-392
Journal of receptor and signal transduction research 2021 Aug;41(4):378-392
W436, a novel SMART derivative, exhibits anti-hepatocarcinoma activity by inducing apoptosis and G2/M cell cycle arrest in vitro and in vivo and induces protective autophagy.
Man S, Wu Z, Sun R, Guan Q, Li Z, Zuo D, Zhang W, Wu Y
Journal of biochemical and molecular toxicology 2021 Aug;35(8):e22831
Journal of biochemical and molecular toxicology 2021 Aug;35(8):e22831
Immunization with recombinant E(rns)-LTB fusion protein elicits protective immune responses against bovine viral diarrhea virus.
Wang SH, Yang GH, Nie JW, Wang J, Wang YX, Du MZ, Guo L, Yang RJ, Zhu YH
Veterinary microbiology 2021 Aug;259:109084
Veterinary microbiology 2021 Aug;259:109084
Downregulation of SUN2 promotes metastasis of colon cancer by activating BDNF/TrkB signalling by interacting with SIRT1.
Liu L, Li SW, Yuan W, Tang J, Sang Y
The Journal of pathology 2021 Aug;254(5):531-542
The Journal of pathology 2021 Aug;254(5):531-542
Procyanidin B2 alleviates liver injury caused by cold stimulation through Sonic hedgehog signalling and autophagy.
Ma L, Li C, Lian S, Xu B, Lv H, Liu Y, Lu J, Ji H, Li S, Guo J, Yang H
Journal of cellular and molecular medicine 2021 Aug;25(16):8015-8027
Journal of cellular and molecular medicine 2021 Aug;25(16):8015-8027
LncRNA MAYA promotes iron overload and hepatocyte senescence through inhibition of YAP in non-alcoholic fatty liver disease.
Yuan P, Qi X, Song A, Ma M, Zhang X, Lu C, Bian M, Lian N, He J, Zheng S, Jin H
Journal of cellular and molecular medicine 2021 Aug;25(15):7354-7366
Journal of cellular and molecular medicine 2021 Aug;25(15):7354-7366
CircPLCE1 facilitates the malignant progression of colorectal cancer by repressing the SRSF2-dependent PLCE1 pre-RNA splicing.
Chen Z, Chen H, Yang L, Li X, Wang Z
Journal of cellular and molecular medicine 2021 Aug;25(15):7244-7256
Journal of cellular and molecular medicine 2021 Aug;25(15):7244-7256
Fisetin mitigates hepatic ischemia-reperfusion injury by regulating GSK3β/AMPK/NLRP3 inflammasome pathway.
Pu JL, Huang ZT, Luo YH, Mou T, Li TT, Li ZT, Wei XF, Wu ZJ
Hepatobiliary & pancreatic diseases international : HBPD INT 2021 Aug;20(4):352-360
Hepatobiliary & pancreatic diseases international : HBPD INT 2021 Aug;20(4):352-360
DDIT3/CHOP promotes autophagy in chondrocytes via SIRT1-AKT pathway.
Yang C, Xu X, Dong X, Yang B, Dong W, Luo Y, Liu X, Wu Y, Wang J
Biochimica et biophysica acta. Molecular cell research 2021 Aug;1868(9):119074
Biochimica et biophysica acta. Molecular cell research 2021 Aug;1868(9):119074
Targeting P2RX1 alleviates renal ischemia/reperfusion injury by preserving mitochondrial dynamics.
Zhuang S, Xia S, Huang P, Wu J, Qu J, Chen R, Sun N, Li D, Wu H, Zhang M, Zhang J, Yuan X, Wang X
Pharmacological research 2021 Aug;170:105712
Pharmacological research 2021 Aug;170:105712
MondoA-Thioredoxin-Interacting Protein Axis Maintains Regulatory T-Cell Identity and Function in Colorectal Cancer Microenvironment.
Lu Y, Li Y, Liu Q, Tian N, Du P, Zhu F, Han Y, Liu X, Liu X, Peng X, Wang X, Wu Y, Tong L, Li Y, Zhu Y, Wu L, Zhang P, Xu Y, Chen H, Li B, Tong X
Gastroenterology 2021 Aug;161(2):575-591.e16
Gastroenterology 2021 Aug;161(2):575-591.e16
Ferroptosis inducer erastin sensitizes NSCLC cells to celastrol through activation of the ROS-mitochondrial fission-mitophagy axis.
Liu M, Fan Y, Li D, Han B, Meng Y, Chen F, Liu T, Song Z, Han Y, Huang L, Chang Y, Cao P, Nakai A, Tan K
Molecular oncology 2021 Aug;15(8):2084-2105
Molecular oncology 2021 Aug;15(8):2084-2105
Momordin Ic induces G0/1 phase arrest and apoptosis in colon cancer cells by suppressing SENP1/c-MYC signaling pathway.
Xianjun F, Xirui X, Jie T, Huiwen M, Shaojun Z, Qiaoyun L, Yunxin L, Xuqun S
Journal of pharmacological sciences 2021 Aug;146(4):249-258
Journal of pharmacological sciences 2021 Aug;146(4):249-258
The active ingredients and mechanisms of Longchai Jiangxue Formula in treating PV, based on UPLC/Q-TOF-MS/MS, systematic pharmacology, and molecular biology validation.
Ming J, Liu W, Wu H, Li Y, Yang E, Wang Z, Xiao H, Quan R, Hu X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Aug;140:111767
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Aug;140:111767
Systematic investigation of the pharmacological mechanism for renal protection by the leaves of Eucommia ulmoides Oliver using UPLC-Q-TOF/MS combined with network pharmacology analysis.
Huang Q, Zhang F, Liu S, Jiang Y, Ouyang D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Aug;140:111735
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Aug;140:111735
Grouper TRAF5 exerts negative regulation on antiviral immune response against iridovirus.
Sun M, Wu S, Zhang X, Zhang L, Kang S, Qin Q, Wei J
Fish & shellfish immunology 2021 Aug;115:7-13
Fish & shellfish immunology 2021 Aug;115:7-13
CSNK2A1-mediated phosphorylation of HMGA2 modulates cisplatin resistance in cervical cancer.
Shi Z, Wu D, Xu H, Yang J, Sun X
FEBS open bio 2021 Aug;11(8):2245-2255
FEBS open bio 2021 Aug;11(8):2245-2255
Lipoxin A4 protects primary spinal cord neurons from Erastin-induced ferroptosis by activating the Akt/Nrf2/HO-1 signaling pathway.
Wei N, Lu T, Yang L, Dong Y, Liu X
FEBS open bio 2021 Aug;11(8):2118-2126
FEBS open bio 2021 Aug;11(8):2118-2126
Bone morphogenetic protein-7 inhibits endothelial-to-mesenchymal transition in primary human umbilical vein endothelial cells and mouse model of systemic sclerosis via Akt/mTOR/p70S6K pathway.
Shen C, Jiang Y, Li Q, Liu C, Hu F, Li M
Journal of dermatological science 2021 Aug;103(2):82-92
Journal of dermatological science 2021 Aug;103(2):82-92
Melatonin mediates monochromatic light-induced expression of somatostatin in the hypothalamus and pituitary of chicks.
Qin X, Liu X, Yan X, Long M, Wang Z, Dong Y, Chen Y, Cao J
Poultry science 2021 Aug;100(8):101285
Poultry science 2021 Aug;100(8):101285
Suramin attenuates intervertebral disc degeneration by inhibiting NF-κB signalling pathway.
Liu ZM, Lu CC, Shen PC, Chou SH, Shih CL, Chen JC, Tien YC
Bone & joint research 2021 Aug;10(8):498-513
Bone & joint research 2021 Aug;10(8):498-513
Extract of Cynomorium songaricum ameliorates mitochondrial ultrastructure impairments and dysfunction in two different in vitro models of Alzheimer's disease.
Cheng D, Su L, Wang X, Li X, Li L, Hu M, Lu Y
BMC complementary medicine and therapies 2021 Aug 9;21(1):206
BMC complementary medicine and therapies 2021 Aug 9;21(1):206
Metformin Is a Pyridoxal-5'-phosphate (PLP)-Competitive Inhibitor of SHMT2.
Tramonti A, Cuyàs E, Encinar JA, Pietzke M, Paone A, Verdura S, Arbusà A, Martin-Castillo B, Giardina G, Joven J, Vazquez A, Contestabile R, Cutruzzolà F, Menendez JA
Cancers 2021 Aug 9;13(16)
Cancers 2021 Aug 9;13(16)
TRIM28 SUMOylates and stabilizes NLRP3 to facilitate inflammasome activation.
Qin Y, Li Q, Liang W, Yan R, Tong L, Jia M, Zhao C, Zhao W
Nature communications 2021 Aug 9;12(1):4794
Nature communications 2021 Aug 9;12(1):4794
Association of CASC18/miR-20a-3p/TGFB2 ceRNA axis with occult lymph node metastasis in tongue squamous cell carcinoma.
Zhou B, Zhou Y, Liu Y, Zhang H, Mao H, Peng M, Xu A, Li Z, Wang H, Tan H, Ren H, Zhou X, Long Y
Molecular medicine (Cambridge, Mass.) 2021 Aug 6;27(1):85
Molecular medicine (Cambridge, Mass.) 2021 Aug 6;27(1):85
DEAD-box helicase 27 enhances stem cell-like properties with poor prognosis in breast cancer.
Li S, Ma J, Zheng A, Song X, Chen S, Jin F
Journal of translational medicine 2021 Aug 6;19(1):334
Journal of translational medicine 2021 Aug 6;19(1):334
METTL3 regulates PM(2.5)-induced cell injury by targeting OSGIN1 in human airway epithelial cells.
Yuan Q, Zhu H, Liu H, Wang M, Chu H, Zhang Z
Journal of hazardous materials 2021 Aug 5;415:125573
Journal of hazardous materials 2021 Aug 5;415:125573
Mammalian target of rapamycin signaling pathway is involved in synaptic plasticity of the spinal dorsal horn and neuropathic pain in rats by regulating autophagy.
Hu J, Chen X, Cheng J, Kong F, Xia H, Wu J
Neuroreport 2021 Aug 4;32(11):925-935
Neuroreport 2021 Aug 4;32(11):925-935
circBTBD7 Promotes Immature Porcine Sertoli Cell Growth through Modulating miR-24-3p/MAPK7 Axis to Inactivate p38 MAPK Signaling Pathway.
Bian Q, Chen B, Weng B, Chu D, Tang X, Yan S, Yin Y, Ran M
International journal of molecular sciences 2021 Aug 30;22(17)
International journal of molecular sciences 2021 Aug 30;22(17)
Targeting Amino Acid Metabolic Reprogramming via L-Type Amino Acid Transporter 1 (LAT1) for Endocrine-Resistant Breast Cancer.
Shindo H, Harada-Shoji N, Ebata A, Sato M, Soga T, Miyashita M, Tada H, Kawai M, Kosaka S, Onuki K, Usami S, Furumoto S, Hayashi S, Abe T, Suzuki T, Ishida T, Sasano H
Cancers 2021 Aug 30;13(17)
Cancers 2021 Aug 30;13(17)
The COL-4A1 polypeptide destroy endothelial cells through the TGF-β/PI3K/AKT pathway.
Li T, Ling Z, Xie K, Wang Y, Miao Z, Ji X, Li J, Hou W, Tang Q, Yuan X, Li N, Li C, Ding H
Scientific reports 2021 Aug 3;11(1):15761
Scientific reports 2021 Aug 3;11(1):15761
CCT5 interacts with cyclin D1 promoting lung adenocarcinoma cell migration and invasion.
Meng Y, Yang L, Wei X, Luo H, Hu Y, Tao X, He J, Zheng X, Xu Q, Luo K, Yu G, Luo Q
Biochemical and biophysical research communications 2021 Aug 27;567:222-229
Biochemical and biophysical research communications 2021 Aug 27;567:222-229
Association of T2285C polymorphism in PARP1 gene coding region with its expression, activity and NSCLC risk along with prognosis.
Wang Y, Xia XB, Tang HZ, Cai JR, Shi XK, Ji HX, Yan XN, Xu T
Mutagenesis 2021 Aug 27;36(4):281-293
Mutagenesis 2021 Aug 27;36(4):281-293
Glyceraldehyde-3-Phosphate Dehydrogenase Restricted in Cytoplasmic Location by Viral GP5 Facilitates Porcine Reproductive and Respiratory Syndrome Virus Replication via Its Glycolytic Activity.
Liu X, Liu X, Bai J, Gao Y, Song Z, Nauwynck H, Wang X, Yang Y, Jiang P
Journal of virology 2021 Aug 25;95(18):e0021021
Journal of virology 2021 Aug 25;95(18):e0021021
Hepatoprotective effect of anemoside B4 against sepsis-induced acute liver injury through modulating the mTOR/p70S6K-mediated autophagy.
Pei L, He L
Chemico-biological interactions 2021 Aug 25;345:109534
Chemico-biological interactions 2021 Aug 25;345:109534
Ten-eleven translocation 1 mediated-DNA hydroxymethylation is required for myelination and remyelination in the mouse brain.
Zhang M, Wang J, Zhang K, Lu G, Liu Y, Ren K, Wang W, Xin D, Xu L, Mao H, Xing J, Gao X, Jin W, Berry K, Mikoshiba K, Wu S, Lu QR, Zhao X
Nature communications 2021 Aug 24;12(1):5091
Nature communications 2021 Aug 24;12(1):5091
Circular RNA CircEYA3 induces energy production to promote pancreatic ductal adenocarcinoma progression through the miR-1294/c-Myc axis.
Rong Z, Shi S, Tan Z, Xu J, Meng Q, Hua J, Liu J, Zhang B, Wang W, Yu X, Liang C
Molecular cancer 2021 Aug 21;20(1):106
Molecular cancer 2021 Aug 21;20(1):106
HIF-1α-activated TM4SF1-AS1 promotes the proliferation, migration, and invasion of hepatocellular carcinoma cells by enhancing TM4SF1 expression.
Zeng Z, Shi Z, Liu Y, Zhao J, Lu Q, Guo J, Liu X, Huang D, Xu Q
Biochemical and biophysical research communications 2021 Aug 20;566:80-86
Biochemical and biophysical research communications 2021 Aug 20;566:80-86
Advanced oxidation protein products impair autophagic flux in macrophage by inducing lysosomal dysfunction via activation of PI3K-Akt-mTOR pathway in Crohn's disease.
Liao Y, Xu J, Qin B, Shi J, Qin C, Xie F, Ou S, Tang J, Wang W, Wu F, Bai L
Free radical biology & medicine 2021 Aug 20;172:33-47
Free radical biology & medicine 2021 Aug 20;172:33-47
MicroRNA-138-1-3p sensitizes sorafenib to hepatocellular carcinoma by targeting PAK5 mediated β-catenin/ABCB1 signaling pathway.
Li TT, Mou J, Pan YJ, Huo FC, Du WQ, Liang J, Wang Y, Zhang LS, Pei DS
Journal of biomedical science 2021 Aug 2;28(1):56
Journal of biomedical science 2021 Aug 2;28(1):56
The RNA m6A reader YTHDF2 controls NK cell antitumor and antiviral immunity.
Ma S, Yan J, Barr T, Zhang J, Chen Z, Wang LS, Sun JC, Chen J, Caligiuri MA, Yu J
The Journal of experimental medicine 2021 Aug 2;218(8)
The Journal of experimental medicine 2021 Aug 2;218(8)
Polysaccharides from Ulva prolifera O.F. Müller inhibit cell proliferation via activating MAPK signaling in A549 and H1650 cells.
Yang JJ, Wang YH, Yin J, Leng H, Shen SD
Food & function 2021 Aug 2;12(15):6915-6924
Food & function 2021 Aug 2;12(15):6915-6924
Ceruloplasmin correlates with immune infiltration and serves as a prognostic biomarker in breast cancer.
Chen F, Han B, Meng Y, Han Y, Liu B, Zhang B, Chang Y, Cao P, Fan Y, Tan K
Aging 2021 Aug 19;13(16):20438-20467
Aging 2021 Aug 19;13(16):20438-20467
Silibinin Suppresses Tumor Cell-Intrinsic Resistance to Nintedanib and Enhances Its Clinical Activity in Lung Cancer.
Bosch-Barrera J, Verdura S, Ruffinelli JC, Carcereny E, Sais E, Cuyàs E, Palmero R, Lopez-Bonet E, Hernández-Martínez A, Oliveras G, Buxó M, Izquierdo A, Morán T, Nadal E, Menendez JA
Cancers 2021 Aug 19;13(16)
Cancers 2021 Aug 19;13(16)
Serum DJ-1 Is a Biomarker of Colorectal Cancer and DJ-1 Activates Mitophagy to Promote Colorectal Cancer Progression.
Chen WT, Yang HB, Ke TW, Liao WL, Hung SY
Cancers 2021 Aug 18;13(16)
Cancers 2021 Aug 18;13(16)
Large-scale and high-resolution mass spectrometry-based proteomics profiling defines molecular subtypes of esophageal cancer for therapeutic targeting.
Liu W, Xie L, He YH, Wu ZY, Liu LX, Bai XF, Deng DX, Xu XE, Liao LD, Lin W, Heng JH, Xu X, Peng L, Huang QF, Li CY, Zhang ZD, Wang W, Zhang GR, Gao X, Wang SH, Li CQ, Xu LY, Liu W, Li EM
Nature communications 2021 Aug 16;12(1):4961
Nature communications 2021 Aug 16;12(1):4961
In vitro assessment of a synergistic combination of gemcitabine and zebularine in pancreatic cancer cells.
Patki M, Saraswat A, Bhutkar S, Dukhande V, Patel K
Experimental cell research 2021 Aug 15;405(2):112660
Experimental cell research 2021 Aug 15;405(2):112660
Microtubule associated protein 4 (MAP4) phosphorylation reduces cardiac microvascular density through NLRP3-related pyroptosis.
Feng YH, Li LF, Zhang Q, Zhang JH, Huang Y, Lv YL, Jia JZ, Zhang D, Hu JY, Huang YS
Cell death discovery 2021 Aug 12;7(1):213
Cell death discovery 2021 Aug 12;7(1):213
KAT2A-mediated AR translocation into nucleus promotes abiraterone-resistance in castration-resistant prostate cancer.
Lu D, Song Y, Yu Y, Wang D, Liu B, Chen L, Li X, Li Y, Cheng L, Lv F, Zhang P, Xing Y
Cell death & disease 2021 Aug 12;12(8):787
Cell death & disease 2021 Aug 12;12(8):787
Metformin attenuates renal tubulointerstitial fibrosis via upgrading autophagy in the early stage of diabetic nephropathy.
Wang F, Sun H, Zuo B, Shi K, Zhang X, Zhang C, Sun D
Scientific reports 2021 Aug 11;11(1):16362
Scientific reports 2021 Aug 11;11(1):16362
Nervous Necrosis Virus Coat Protein Mediates Host Translation Shutoff through Nuclear Translocalization and Degradation of Polyadenylate Binding Protein.
Cheng CA, Luo JM, Chiang MH, Fang KY, Li CH, Chen CW, Wang YS, Chang CY
Journal of virology 2021 Aug 10;95(17):e0236420
Journal of virology 2021 Aug 10;95(17):e0236420
Ophiocordyceps lanpingensis polysaccharides alleviate chronic kidney disease through MAPK/NF-κB pathway.
Zhou S, He Y, Zhang W, Xiong Y, Jiang L, Wang J, Cui X, Qu Y, Ge F
Journal of ethnopharmacology 2021 Aug 10;276:114189
Journal of ethnopharmacology 2021 Aug 10;276:114189
LncRNA LINC00680 promotes lung adenocarcinoma growth via binding to GATA6 and canceling GATA6-mediated suppression of SOX12 expression.
Sun X, Wang R, Tan M, Tian X, Meng J
Experimental cell research 2021 Aug 1;405(1):112653
Experimental cell research 2021 Aug 1;405(1):112653
Empagliflozin, a sodium glucose cotransporter-2 inhibitor, ameliorates peritoneal fibrosis via suppressing TGF-β/Smad signaling.
Shentu Y, Li Y, Xie S, Jiang H, Sun S, Lin R, Chen C, Bai Y, Zhang Y, Zheng C, Zhou Y
International immunopharmacology 2021 Apr;93:107374
International immunopharmacology 2021 Apr;93:107374
Ergosterol peroxide exhibits antiviral and immunomodulatory abilities against porcine deltacoronavirus (PDCoV) via suppression of NF-κB and p38/MAPK signaling pathways in vitro.
Duan C, Ge X, Wang J, Wei Z, Feng WH, Wang J
International immunopharmacology 2021 Apr;93:107317
International immunopharmacology 2021 Apr;93:107317
LncRNA ABCC6P1 promotes proliferation and migration of papillary thyroid cancer cells via Wnt/β-catenin signaling pathway.
Guan Y, Li Y, Yang QB, Yu J, Qiao H
Annals of translational medicine 2021 Apr;9(8):664
Annals of translational medicine 2021 Apr;9(8):664
Limonin induces apoptosis of HL-60 cells by inhibiting NQO1 activity.
Chen Y, Liang J, Liang X, Chen J, Wang Y, Cao J, Sun C, Ye J, Chen Q
Food science & nutrition 2021 Apr;9(4):1860-1869
Food science & nutrition 2021 Apr;9(4):1860-1869
Melatonin Ameliorates Lipopolysaccharide-Induced Microglial Inflammation via Triggering SIRT1/HMGB1 Signaling Axis.
Chibaatar E, Le K, Abdoulaye IA, Wu S, Guo Y
Journal of molecular neuroscience : MN 2021 Apr;71(4):691-701
Journal of molecular neuroscience : MN 2021 Apr;71(4):691-701
Pooled CRISPR screening identifies m(6)A as a positive regulator of macrophage activation.
Tong J, Wang X, Liu Y, Ren X, Wang A, Chen Z, Yao J, Mao K, Liu T, Meng FL, Pan W, Zou Q, Liu J, Zhou Y, Xia Q, Flavell RA, Zhu S, Li HB
Science advances 2021 Apr;7(18)
Science advances 2021 Apr;7(18)
Bio-inspired chiral self-assemblies promoted neuronal differentiation of retinal progenitor cells through activation of metabolic pathway.
Sun N, Dou X, Tang Z, Zhang D, Ni N, Wang J, Gao H, Ju Y, Dai X, Zhao C, Gu P, Ji J, Feng C
Bioactive materials 2021 Apr;6(4):990-997
Bioactive materials 2021 Apr;6(4):990-997
Perilipin 4 Protein: an Impending Target for Amyotrophic Lateral Sclerosis.
Zhu L, Hu F, Li C, Zhang C, Hang R, Xu R
Molecular neurobiology 2021 Apr;58(4):1723-1737
Molecular neurobiology 2021 Apr;58(4):1723-1737
Inhibition of soluble epoxide hydrolase (sEH) protects hippocampal neurons and reduces cognitive decline in type 2 diabetic mice.
Wu J, Fan Z, Zhao Y, Chen Q, Xiao Q
The European journal of neuroscience 2021 Apr;53(8):2532-2540
The European journal of neuroscience 2021 Apr;53(8):2532-2540
Let-7 mediated airway remodelling in chronic obstructive pulmonary disease via the regulation of IL-6.
Di T, Yang Y, Fu C, Zhang Z, Qin C, Sai X, Liu J, Hu C, Zheng M, Wu Y, Bian T
European journal of clinical investigation 2021 Apr;51(4):e13425
European journal of clinical investigation 2021 Apr;51(4):e13425
Expression of lncRNA CCAT2 in children with neuroblastoma and its effect on cancer cell growth.
Chen M, Zhao M, Hou Y, Zhu B
Molecular and cellular biochemistry 2021 Apr;476(4):1871-1879
Molecular and cellular biochemistry 2021 Apr;476(4):1871-1879
Induction of NUPR1 and AP‑1 contributes to the carcinogenic potential of nickel.
Murphy A, Roy N, Sun H, Jin C, Costa M
Oncology reports 2021 Apr;45(4)
Oncology reports 2021 Apr;45(4)
Anti-thrombotic activity of phenolic acids obtained from Salvia miltiorrhiza f. alba in TNF-α-stimulated endothelial cells via the NF-κB/JNK/p38 MAPK signaling pathway.
Zheng X, Liu H, Ma M, Ji J, Zhu F, Sun L
Archives of pharmacal research 2021 Apr;44(4):427-438
Archives of pharmacal research 2021 Apr;44(4):427-438
miR-182-5p and miR-96-5p Target PIAS1 and Mediate the Negative Feedback Regulatory Loop between PIAS1 and STAT3 in Endometrial Cancer.
Xiao Y, Huang W, Huang H, Wang L, Wang M, Zhang T, Fang X, Xia X
DNA and cell biology 2021 Apr;40(4):618-628
DNA and cell biology 2021 Apr;40(4):618-628
CRISPR/Cas9 library screening uncovered methylated PKP2 as a critical driver of lung cancer radioresistance by stabilizing β-catenin.
Cheng C, Pei X, Li SW, Yang J, Li C, Tang J, Hu K, Huang G, Min WP, Sang Y
Oncogene 2021 Apr;40(16):2842-2857
Oncogene 2021 Apr;40(16):2842-2857
The orphan nuclear receptor Nurr1 agonist amodiaquine mediates neuroprotective effects in 6-OHDA Parkinson's disease animal model by enhancing the phosphorylation of P38 mitogen-activated kinase but not PI3K/AKT signaling pathway.
Kambey PA, Chengcheng M, Xiaoxiao G, Abdulrahman AA, Kanwore K, Nadeem I, Jiao W, Gao D
Metabolic brain disease 2021 Apr;36(4):609-625
Metabolic brain disease 2021 Apr;36(4):609-625
Programmed cell death 4 modulates lysosomal function by inhibiting TFEB translation.
Chen X, Guan Y, Zhang Y, Jia Y, Li W, Guo C, Li Y, Wang X, Shi Y, Wang Q, Zhu F, Li Y, Zhang L
Cell death and differentiation 2021 Apr;28(4):1237-1250
Cell death and differentiation 2021 Apr;28(4):1237-1250
ARFGAP1 binds to classical swine fever virus NS5A protein and enhances CSFV replication in PK-15 cells.
Zhang L, Jin M, Song M, Liu S, Wang T, Guo K, Zhang Y
Veterinary microbiology 2021 Apr;255:109034
Veterinary microbiology 2021 Apr;255:109034
MARCH5 restores endothelial cell function against ischaemic/hypoxia injury via Akt/eNOS pathway.
Lei W, Li J, Li C, Chen L, Huang F, Xiao D, Zhang J, Zhao J, Li G, Qu T, Zhou H, Liao Y, Chen M
Journal of cellular and molecular medicine 2021 Apr;25(7):3182-3193
Journal of cellular and molecular medicine 2021 Apr;25(7):3182-3193
Method used to establish a large animal model of drug-induced acute kidney injury.
Wang SY, Zhang CY, Cai GY, Chen XM
Experimental biology and medicine (Maywood, N.J.) 2021 Apr;246(8):986-995
Experimental biology and medicine (Maywood, N.J.) 2021 Apr;246(8):986-995
Postnatal growth retardation is associated with deteriorated intestinal mucosal barrier function using a porcine model.
Qi M, Tan B, Wang J, Liao S, Li J, Cui Z, Shao Y, Ji P, Yin Y
Journal of cellular physiology 2021 Apr;236(4):2631-2648
Journal of cellular physiology 2021 Apr;236(4):2631-2648
[Effect of astragaloside IV on the expression of NOD-like receptor protein 3 inflammasome in neonatal rats with hypoxic-ischemic brain damage].
Li N, Mu YP, Liu CY, Wang Y, Li XF, Wang XW
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 2021 Apr;23(4):402-409
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 2021 Apr;23(4):402-409
LncIHAT Is Induced by Hypoxia-Inducible Factor 1 and Promotes Breast Cancer Progression.
Chen L, Bao L, Niu Y, Wang JE, Kumar A, Xing C, Wang Y, Luo W
Molecular cancer research : MCR 2021 Apr;19(4):678-687
Molecular cancer research : MCR 2021 Apr;19(4):678-687
Cigarette smoke extract amplifies NADPH oxidase-dependent ROS production to inactivate PTEN by oxidation in BEAS-2B cells.
Cai B, Liu M, Li J, Xu D, Li J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Apr;150:112050
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Apr;150:112050
Low-dose naltrexone plays antineoplastic role in cervical cancer progression through suppressing PI3K/AKT/mTOR pathway.
Liu N, Yan L, Shan F, Wang X, Qu N, Handley MK, Ma M
Translational oncology 2021 Apr;14(4):101028
Translational oncology 2021 Apr;14(4):101028
The S100 calcium-binding protein A11 promotes hepatic steatosis through RAGE-mediated AKT-mTOR signaling.
Teng F, Jiang J, Zhang J, Yuan Y, Li K, Zhou B, Zhou X, Liu W, Zhang P, Liu D, Zheng M, Lu Y, Zhang H
Metabolism: clinical and experimental 2021 Apr;117:154725
Metabolism: clinical and experimental 2021 Apr;117:154725
Resveratrol Attenuates Meningitic Escherichia coli-Mediated Blood-Brain Barrier Disruption.
Yang R, Lv Y, Miao L, Zhang H, Qu X, Chen J, Xu B, Yang B, Fu J, Tan C, Chen H, Wang X
ACS infectious diseases 2021 Apr 9;7(4):777-789
ACS infectious diseases 2021 Apr 9;7(4):777-789
PolyQ-expanded proteins impair cellular proteostasis of ataxin-3 through sequestering the co-chaperone HSJ1 into aggregates.
Yue HW, Hong JY, Zhang SX, Jiang LL, Hu HY
Scientific reports 2021 Apr 9;11(1):7815
Scientific reports 2021 Apr 9;11(1):7815
N(6)-methyladenosine-binding protein YTHDF1 suppresses EBV replication and promotes EBV RNA decay.
Xia TL, Li X, Wang X, Zhu YJ, Zhang H, Cheng W, Chen ML, Ye Y, Li Y, Zhang A, Dai DL, Zhu QY, Yuan L, Zheng J, Huang H, Chen SQ, Xiao ZW, Wang HB, Roy G, Zhong Q, Lin D, Zeng YX, Wang J, Zhao B, Gewurz BE, Chen J, Zuo Z, Zeng MS
EMBO reports 2021 Apr 7;22(4):e50128
EMBO reports 2021 Apr 7;22(4):e50128
ASIC1 and ASIC3 mediate cellular senescence of human nucleus pulposus mesenchymal stem cells during intervertebral disc degeneration.
Ding J, Zhang R, Li H, Ji Q, Cheng X, Thorne RF, Hondermarck H, Liu X, Shen C
Aging 2021 Apr 6;13(7):10703-10723
Aging 2021 Apr 6;13(7):10703-10723
EGFR-ERK induced activation of GRHL1 promotes cell cycle progression by up-regulating cell cycle related genes in lung cancer.
He Y, Gan M, Wang Y, Huang T, Wang J, Han T, Yu B
Cell death & disease 2021 Apr 30;12(5):430
Cell death & disease 2021 Apr 30;12(5):430
miR-190 promotes malignant transformation and progression of human urothelial cells through CDKN1B/p27 inhibition.
Huang S, Hua X, Kuang M, Zhu J, Mu H, Tian Z, Zheng X, Xie Q
Cancer cell international 2021 Apr 29;21(1):241
Cancer cell international 2021 Apr 29;21(1):241
Pterostilbene, a Dimethylether Analogue of Resveratrol, Possesses High Potency in the Prevention of Platelet Activation in Humans and the Reduction of Vascular Thrombosis in Mice.
Huang WC, Liu JC, Hsia CW, Fong TH, Hsia CH, Tran OT, Velusamy M, Yang CH, Sheu JR
Journal of agricultural and food chemistry 2021 Apr 28;69(16):4697-4707
Journal of agricultural and food chemistry 2021 Apr 28;69(16):4697-4707
Fludarabine Inhibits Infection of Zika Virus, SFTS Phlebovirus, and Enterovirus A71.
Gao C, Wen C, Li Z, Lin S, Gao S, Ding H, Zou P, Xing Z, Yu Y
Viruses 2021 Apr 27;13(5)
Viruses 2021 Apr 27;13(5)
Dynamic evolution of emphysema and airway remodeling in two mouse models of COPD.
Yang Y, Di T, Zhang Z, Liu J, Fu C, Wu Y, Bian T
BMC pulmonary medicine 2021 Apr 26;21(1):134
BMC pulmonary medicine 2021 Apr 26;21(1):134
Leukemia inhibitory factor regulates Schwann cell proliferation and migration and affects peripheral nerve regeneration.
Chen Q, Liu Q, Zhang Y, Li S, Yi S
Cell death & disease 2021 Apr 22;12(5):417
Cell death & disease 2021 Apr 22;12(5):417
Circ11103 Interacts with miR-128/PPARGC1A to Regulate Milk Fat Metabolism in Dairy Cows.
Chen Z, Lu Q, Liang Y, Cui X, Wang X, Mao Y, Yang Z
Journal of agricultural and food chemistry 2021 Apr 21;69(15):4490-4500
Journal of agricultural and food chemistry 2021 Apr 21;69(15):4490-4500
H(2)O(2) enhances the anticancer activity of TMPyP4 by ROS-mediated mitochondrial dysfunction and DNA damage.
Chen J, Jin X, Shen Z, Mei Y, Zhu J, Zhang X, Liang G, Zheng X
Medical oncology (Northwood, London, England) 2021 Apr 21;38(6):59
Medical oncology (Northwood, London, England) 2021 Apr 21;38(6):59
Buprenorphine alters microglia and astrocytes acutely following diffuse traumatic brain injury.
Ryu J, Stone P, Lee S, Payne B, Gorse K, Lafrenaye A
Scientific reports 2021 Apr 21;11(1):8620
Scientific reports 2021 Apr 21;11(1):8620
CK2 Activity Mediates the Aggressive Molecular Signature of Glioblastoma Multiforme by Inducing Nerve/Glial Antigen (NG)2 Expression.
Schmitt BM, Boewe AS, Götz C, Philipp SE, Urbschat S, Oertel J, Menger MD, Laschke MW, Ampofo E
Cancers 2021 Apr 2;13(7)
Cancers 2021 Apr 2;13(7)
Identification of a mesenchymal-related signature associated with clinical prognosis in glioma.
Zhang Z, Chen J, Huo X, Zong G, Huang K, Cheng M, Sun L, Yue X, Bian E, Zhao B
Aging 2021 Apr 19;13(9):12431-12455
Aging 2021 Apr 19;13(9):12431-12455
Btk knockout attenuates the liver inflammation in STZ-induced diabetic mice by suppressing NLRP3 inflammasome activation.
Li Y, Zhao J, Wu Y, Xia L
Biochemical and biophysical research communications 2021 Apr 16;549:75-82
Biochemical and biophysical research communications 2021 Apr 16;549:75-82
Chemoproteomics-enabled discovery of covalent RNF114-based degraders that mimic natural product function.
Luo M, Spradlin JN, Boike L, Tong B, Brittain SM, McKenna JM, Tallarico JA, Schirle M, Maimone TJ, Nomura DK
Cell chemical biology 2021 Apr 15;28(4):559-566.e15
Cell chemical biology 2021 Apr 15;28(4):559-566.e15
Loss of Mitochondrial Protease CLPP Activates Type I IFN Responses through the Mitochondrial DNA-cGAS-STING Signaling Axis.
Torres-Odio S, Lei Y, Gispert S, Maletzko A, Key J, Menissy SS, Wittig I, Auburger G, West AP
Journal of immunology (Baltimore, Md. : 1950) 2021 Apr 15;206(8):1890-1900
Journal of immunology (Baltimore, Md. : 1950) 2021 Apr 15;206(8):1890-1900
AKR1B10 negatively regulates autophagy through reducing GAPDH upon glucose starvation in colon cancer.
Li W, Liu C, Huang Z, Shi L, Zhong C, Zhou W, Meng P, Li Z, Wang S, Luo F, Yan J, Wu T
Journal of cell science 2021 Apr 15;134(8)
Journal of cell science 2021 Apr 15;134(8)
Kisspeptin-10 Maintains the Activation of the mTOR Signaling Pathway by Inhibiting SIRT6 to Promote the Synthesis of Milk in Bovine Mammary Epithelial Cells.
Cao Y, Hu G, Zhang Q, Ma L, Wang J, Li W, Ge Y, Cheng J, Yang Z, Fu S, Liu J
Journal of agricultural and food chemistry 2021 Apr 14;69(14):4093-4100
Journal of agricultural and food chemistry 2021 Apr 14;69(14):4093-4100
AIF3 splicing switch triggers neurodegeneration.
Liu S, Zhou M, Ruan Z, Wang Y, Chang C, Sasaki M, Rajaram V, Lemoff A, Nambiar K, Wang JE, Hatanpaa KJ, Luo W, Dawson TM, Dawson VL, Wang Y
Molecular neurodegeneration 2021 Apr 14;16(1):25
Molecular neurodegeneration 2021 Apr 14;16(1):25
An Experimentally Induced Mutation in the UBA Domain of p62 Changes the Sensitivity of Cisplatin by Up-Regulating HK2 Localisation on the Mitochondria and Increasing Mitophagy in A2780 Ovarian Cancer Cells.
Yu S, Yan X, Tian R, Xu L, Zhao Y, Sun L, Su J
International journal of molecular sciences 2021 Apr 13;22(8)
International journal of molecular sciences 2021 Apr 13;22(8)
Nonsegmented Negative-Sense RNA Viruses Utilize N(6)-Methyladenosine (m(6)A) as a Common Strategy To Evade Host Innate Immunity.
Lu M, Xue M, Wang HT, Kairis EL, Ahmad S, Wei J, Zhang Z, Liu Q, Zhang Y, Gao Y, Garcin D, Peeples ME, Sharma A, Hur S, He C, Li J
Journal of virology 2021 Apr 12;95(9)
Journal of virology 2021 Apr 12;95(9)
Kaempferol induces ROS-dependent apoptosis in pancreatic cancer cells via TGM2-mediated Akt/mTOR signaling.
Wang F, Wang L, Qu C, Chen L, Geng Y, Cheng C, Yu S, Wang D, Yang L, Meng Z, Chen Z
BMC cancer 2021 Apr 12;21(1):396
BMC cancer 2021 Apr 12;21(1):396
Effect of Shuangdan Mingmu capsule, a Chinese herbal formula, on oxidative stress-induced apoptosis of pericytes through PARP/GAPDH pathway.
Nie F, Yan J, Ling Y, Liu Z, Fu C, Li X, Qin Y
BMC complementary medicine and therapies 2021 Apr 10;21(1):118
BMC complementary medicine and therapies 2021 Apr 10;21(1):118
TET1 may contribute to hypoxia-induced epithelial to mesenchymal transition of endometrial epithelial cells in endometriosis.
Wu J, Li X, Huang H, Xia X, Zhang M, Fang X
PeerJ 2020;8:e9950
PeerJ 2020;8:e9950
Lycopene alleviates oxidative stress via the PI3K/Akt/Nrf2pathway in a cell model of Alzheimer's disease.
Fang Y, Ou S, Wu T, Zhou L, Tang H, Jiang M, Xu J, Guo K
PeerJ 2020;8:e9308
PeerJ 2020;8:e9308
Tethering of Telomeres to the Nuclear Envelope Is Mediated by SUN1-MAJIN and Possibly Promoted by SPDYA-CDK2 During Meiosis.
Wang G, Wu X, Zhou L, Gao S, Yun D, Liang A, Sun F
Frontiers in cell and developmental biology 2020;8:845
Frontiers in cell and developmental biology 2020;8:845
Enterohemorrhagic Escherichia coli Effector Protein EspF Interacts With Host Protein ANXA6 and Triggers Myosin Light Chain Kinase (MLCK)-Dependent Tight Junction Dysregulation.
Hua Y, Wu J, Fu M, Liu J, Li X, Zhang B, Zhao W, Wan C
Frontiers in cell and developmental biology 2020;8:613061
Frontiers in cell and developmental biology 2020;8:613061
Safrana l Prevents Prostate Cancer Recurrence by Blocking the Re-activation of Quiescent Cancer Cells via Downregulation of S-Phase Kinase-Associated Protein 2.
Jiang X, Li Y, Feng JL, Nik Nabil WN, Wu R, Lu Y, Liu H, Xi ZC, Xu HX
Frontiers in cell and developmental biology 2020;8:598620
Frontiers in cell and developmental biology 2020;8:598620
miR-7-5p Affects Brain Edema After Intracerebral Hemorrhage and Its Possible Mechanism.
Chen X, Deng S, Lei Q, He Q, Ren Y, Zhang Y, Nie J, Lu W
Frontiers in cell and developmental biology 2020;8:598020
Frontiers in cell and developmental biology 2020;8:598020
Amnion-Derived Mesenchymal Stem Cell Exosomes-Mediated Autophagy Promotes the Survival of Trophoblasts Under Hypoxia Through mTOR Pathway by the Downregulation of EZH2.
Chu Y, Chen W, Peng W, Liu Y, Xu L, Zuo J, Zhou J, Zhang Y, Zhang N, Li J, Liu L, Yao K, Gao G, Wang X, Han R, Liu C, Li Y, Zhou H, Huang Y, Ye Y
Frontiers in cell and developmental biology 2020;8:545852
Frontiers in cell and developmental biology 2020;8:545852
C2C12 Mouse Myoblasts Damage Induced by Oxidative Stress Is Alleviated by the Antioxidant Capacity of the Active Substance Phloretin.
Li J, Yang Q, Han L, Pan C, Lei C, Chen H, Lan X
Frontiers in cell and developmental biology 2020;8:541260
Frontiers in cell and developmental biology 2020;8:541260
Ferroptosis-Related Gene Signature Predicts Glioma Cell Death and Glioma Patient Progression.
Liu HJ, Hu HM, Li GZ, Zhang Y, Wu F, Liu X, Wang KY, Zhang CB, Jiang T
Frontiers in cell and developmental biology 2020;8:538
Frontiers in cell and developmental biology 2020;8:538
miR-205 Expression Elevated With EDS Treatment and Induced Leydig Cell Apoptosis by Targeting RAP2B via the PI3K/AKT Signaling Pathway.
Cui Y, Chen R, Ma L, Yang W, Chen M, Zhang Y, Yu S, Dong W, Zeng W, Lan X, Pan C
Frontiers in cell and developmental biology 2020;8:448
Frontiers in cell and developmental biology 2020;8:448
Ketamine ameliorates hypoxia-induced endothelial injury in human umbilical vein endothelial cells.
Zhou X, Liu J, Yang S, Su Y, Meng Z, Hu Y
Clinics (Sao Paulo, Brazil) 2020;75:e1865
Clinics (Sao Paulo, Brazil) 2020;75:e1865
Cdk5 Inhibitory Peptide Prevents Loss of Neurons and Alleviates Behavioral Changes in p25 Transgenic Mice.
Huang Y, Huang W, Huang Y, Song P, Zhang M, Zhang HT, Pan S, Hu Y
Journal of Alzheimer's disease : JAD 2020;74(4):1231-1242
Journal of Alzheimer's disease : JAD 2020;74(4):1231-1242
Maternal Methyl-Donor Micronutrient Supplementation During Pregnancy Promotes Skeletal Muscle Differentiation and Maturity in Newborn and Weaning Pigs.
He Q, Zou T, Chen J, Jian L, He J, Xia Y, Xie F, Wang Z, You J
Frontiers in nutrition 2020;7:609022
Frontiers in nutrition 2020;7:609022
Potential Role of SLC5A8 Expression in the Etiology of Subacute Ruminal Acidosis.
Zhao C, Bobe G, Wang Y, Zhang X, Zhao Z, Zhang S, Sun G, Yuan X, Li X, Liu G
Frontiers in veterinary science 2020;7:394
Frontiers in veterinary science 2020;7:394
miR-124-3p Suppresses the Invasiveness and Metastasis of Hepatocarcinoma Cells via Targeting CRKL.
Majid A, Wang J, Nawaz M, Abdul S, Ayesha M, Guo C, Liu Q, Liu S, Sun MZ
Frontiers in molecular biosciences 2020;7:223
Frontiers in molecular biosciences 2020;7:223
MicroRNA-362-3p Inhibits Migration and Invasion via Targeting BCAP31 in Cervical Cancer.
Yang S, Zhang X, Sun Y, Shi J, Jiang D, Wang J, Liu Y, Hu C, Pan J, Zheng L, Yang K
Frontiers in molecular biosciences 2020;7:107
Frontiers in molecular biosciences 2020;7:107
Metformin effectively treats Tsc1 deletion-caused kidney pathology by upregulating AMPK phosphorylation.
Fang Y, Li F, Qi C, Mao X, Wang F, Zhao Z, Chen JK, Zhang Z, Wu H
Cell death discovery 2020;6:52
Cell death discovery 2020;6:52
miR-143-3p inhibition promotes neuronal survival in an Alzheimer's disease cell model by targeting neuregulin-1.
Sun C, Jia N, Li R, Zhang Z, Zhong Y, Han K
Folia neuropathologica 2020;58(1):10-21
Folia neuropathologica 2020;58(1):10-21
Modulation of Wnt/β-catenin signaling in IL-17A-mediated macrophage polarization of RAW264.7 cells.
Yuan C, Yang D, Ma J, Yang J, Xue J, Song F, Liu X
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2020;53(8):e9488
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2020;53(8):e9488
Antrodia Cinnamomea Attenuates Non-Alcoholic Steatohepatitis by Suppressing NLRP3 Inflammasome Activation In Vitro and In Vivo.
Yen IC, Lin JC, Chen Y, Tu QW, Lee SY
The American journal of Chinese medicine 2020;48(8):1859-1874
The American journal of Chinese medicine 2020;48(8):1859-1874
Koumine Alleviates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction in IPEC-J2 Cells by Regulating Nrf2/NF-κB Pathway.
Wu J, Yang CL, Sha YK, Wu Y, Liu ZY, Yuan ZH, Sun ZL
The American journal of Chinese medicine 2020;48(1):127-142
The American journal of Chinese medicine 2020;48(1):127-142
Osthole Improves Cognitive Function of Vascular Dementia Rats: Reducing Aβ Deposition via Inhibition NLRP3 Inflammasome.
Liu Y, Chen X, Gong Q, Shi J, Li F
Biological & pharmaceutical bulletin 2020;43(9):1315-1323
Biological & pharmaceutical bulletin 2020;43(9):1315-1323
Dietary Baicalin Zinc Supplementation Alleviates Oxidative Stress and Enhances Nutrition Absorption in Deoxynivalenol Challenged Pigs.
Zha A, Cui Z, Qi M, Liao S, Chen L, Liao P, Tan B
Current drug metabolism 2020;21(8):614-625
Current drug metabolism 2020;21(8):614-625
Heme Oxygenase-1-Mediated Autophagy Protects against Oxidative Damage in Rat Nucleus Pulposus-Derived Mesenchymal Stem Cells.
Chen S, Liu S, Zhao L, Lin H, Ma K, Shao Z
Oxidative medicine and cellular longevity 2020;2020:9349762
Oxidative medicine and cellular longevity 2020;2020:9349762
Environmental Pollutant Benzo[a]pyrene Induces Recurrent Pregnancy Loss through Promoting Apoptosis and Suppressing Migration of Extravillous Trophoblast.
Ye Y, Jiang S, Zhang C, Cheng Y, Zhong H, Du T, Xu W, Azziz R, Zhang H, Zhao X
BioMed research international 2020;2020:8983494
BioMed research international 2020;2020:8983494
Disease Mutation Study Identifies Critical Residues for Phosphatidylserine Flippase ATP11A.
Sun K, Tian W, Li X, Liu W, Yang Y, Zhu X
BioMed research international 2020;2020:7342817
BioMed research international 2020;2020:7342817
Rhein Suppresses Neuroinflammation via Multiple Signaling Pathways in LPS-Stimulated BV2 Microglia Cells.
Zheng P, Tian X, Zhang W, Yang Z, Zhou J, Zheng J, Cui H, Tang T, Luo J, Wang Y
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7210627
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7210627
Hydrogen Gas Attenuates Hypoxic-Ischemic Brain Injury via Regulation of the MAPK/HO-1/PGC-1a Pathway in Neonatal Rats.
Wang P, Zhao M, Chen Z, Wu G, Fujino M, Zhang C, Zhou W, Zhao M, Hirano SI, Li XK, Zhao L
Oxidative medicine and cellular longevity 2020;2020:6978784
Oxidative medicine and cellular longevity 2020;2020:6978784
Human Tissue Kallikrein 1 Improves Erectile Dysfunction of Streptozotocin-Induced Diabetic Rats by Inhibition of Excessive Oxidative Stress and Activation of the PI3K/AKT/eNOS Pathway.
Luan Y, Cui K, Tang Z, Ruan Y, Liu K, Wang T, Chen Z, Wang S, Liu J
Oxidative medicine and cellular longevity 2020;2020:6834236
Oxidative medicine and cellular longevity 2020;2020:6834236
Bergenin Attenuates Hepatic Fibrosis by Regulating Autophagy Mediated by the PPAR-γ/TGF-β Pathway.
Xia Y, Li J, Chen K, Feng J, Guo C
PPAR research 2020;2020:6694214
PPAR research 2020;2020:6694214
Hyperglycemia Induces Endoplasmic Reticulum Stress in Atrial Cardiomyocytes, and Mitofusin-2 Downregulation Prevents Mitochondrial Dysfunction and Subsequent Cell Death.
Yuan M, Gong M, Zhang Z, Meng L, Tse G, Zhao Y, Bao Q, Zhang Y, Yuan M, Liu X, Li G, Liu T
Oxidative medicine and cellular longevity 2020;2020:6569728
Oxidative medicine and cellular longevity 2020;2020:6569728
Mild Hypothermia Attenuates Hepatic Ischemia-Reperfusion Injury through Regulating the JAK2/STAT3-CPT1a-Dependent Fatty Acid β-Oxidation.
Wang W, Hu X, Xia Z, Liu Z, Zhong Z, Lu Z, Liu A, Ye S, Cao Q, Wang Y, Zhu F, Ye Q
Oxidative medicine and cellular longevity 2020;2020:5849794
Oxidative medicine and cellular longevity 2020;2020:5849794
Dexmedetomidine Attenuates Neurotoxicity in Developing Rats Induced by Sevoflurane through Upregulating BDNF-TrkB-CREB and Downregulating ProBDNF-P75NRT-RhoA Signaling Pathway.
Dong Y, Hong W, Tang Z, Gao Y, Wu X, Liu H
Mediators of inflammation 2020;2020:5458061
Mediators of inflammation 2020;2020:5458061
NLRC3 Delays the Progression of AD in APP/PS1 Mice via Inhibiting PI3K Activation.
Zha L, Yu Z, Fang J, Zhou L, Guo W, Zhou J
Oxidative medicine and cellular longevity 2020;2020:5328031
Oxidative medicine and cellular longevity 2020;2020:5328031
Qingjie Fuzheng Granule Inhibited the Migration and Invasion of Colorectal Cancer Cells by Regulating the lncRNA ANRIL/let-7a/TGF-β1/Smad Axis.
Zhang L, Liu J, Lin S, Tan J, Huang B, Lin J
Evidence-based complementary and alternative medicine : eCAM 2020;2020:5264651
Evidence-based complementary and alternative medicine : eCAM 2020;2020:5264651
The Nrf2/PGC1α Pathway Regulates Antioxidant and Proteasomal Activity to Alter Cisplatin Sensitivity in Ovarian Cancer.
Deng X, Lin N, Fu J, Xu L, Luo H, Jin Y, Liu Y, Sun L, Su J
Oxidative medicine and cellular longevity 2020;2020:4830418
Oxidative medicine and cellular longevity 2020;2020:4830418
Congrong Shujing Granule-Induced GRP78 Expression Reduced Endoplasmic Reticulum Stress and Neuronal Apoptosis in the Midbrain in a Parkinson's Disease Rat Model.
Xu Q, Yang S, Wu F, Lin Y, Zhong J, Tang L, Hu X, Cai J
Evidence-based complementary and alternative medicine : eCAM 2020;2020:4796236
Evidence-based complementary and alternative medicine : eCAM 2020;2020:4796236
LncRNA CAR10 Upregulates PDPK1 to Promote Cervical Cancer Development by Sponging miR-125b-5p.
Hu T, Zhang Q, Gao L
BioMed research international 2020;2020:4351671
BioMed research international 2020;2020:4351671
Fasting Induces Hepatocellular Carcinoma Cell Apoptosis by Inhibiting SET8 Expression.
Qi J, Chen X, Wu Q, Wang J, Zhang H, Mao A, Zhu M, Miao C
Oxidative medicine and cellular longevity 2020;2020:3985089
Oxidative medicine and cellular longevity 2020;2020:3985089
Tyrosine Kinase Receptors Axl and MerTK Mediate the Beneficial Effect of Electroacupuncture in a Cuprizone-Induced Demyelinating Model.
Zou Z, Sun J, Kang Z, Wang Y, Zhao H, Zhu K, Wang J
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3205176
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3205176
Gubenzhike Recipe Ameliorates Respiratory Mucosal Immunity in Mice with Chronic Obstructive Pulmonary Disease through Upregulation of the γδT Lymphocytes and KGF Levels.
Wang YQ, Liao Q, Tang SH, Cai Z, Zhang HC
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3056797
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3056797
Hypouricemic Effects of Extracts from Urtica hyperborea Jacq. ex Wedd. in Hyperuricemia Mice through XOD, URAT1, and OAT1.
Han S, Wei R, Han D, Zhu J, Luo W, Ao W, Zhong G
BioMed research international 2020;2020:2968135
BioMed research international 2020;2020:2968135
Gentiopicroside Ameliorates Oxidative Stress and Lipid Accumulation through Nuclear Factor Erythroid 2-Related Factor 2 Activation.
Jin M, Feng H, Wang Y, Yan S, Shen B, Li Z, Qin H, Wang Q, Li J, Liu G
Oxidative medicine and cellular longevity 2020;2020:2940746
Oxidative medicine and cellular longevity 2020;2020:2940746
Mechanisms of Cong Rong Shu Jing Compound Effects on Endoplasmic Reticulum Stress in a Rat Model of Parkinson's Disease.
Lin Y, Tang L, Huang P, Liu T, Zhong J, Xu Q, Li X, Lin Y, Xiao S, Cai J
Evidence-based complementary and alternative medicine : eCAM 2020;2020:1818307
Evidence-based complementary and alternative medicine : eCAM 2020;2020:1818307
N-Butanol Extract of Gastrodia elata Suppresses Inflammatory Responses in Lipopolysaccharide-Stimulated Macrophages and Complete Freund's Adjuvant- (CFA-) Induced Arthritis Rats via Inhibition of MAPK Signaling Pathway.
He P, Hu Y, Huang C, Wang X, Zhang H, Zhang X, Dai H, Wang R, Gao Y
Evidence-based complementary and alternative medicine : eCAM 2020;2020:1658618
Evidence-based complementary and alternative medicine : eCAM 2020;2020:1658618
Effect of Thymoquinone on Acute Kidney Injury Induced by Sepsis in BALB/c Mice.
Guo LP, Liu SX, Yang Q, Liu HY, Xu LL, Hao YH, Zhang XQ
BioMed research international 2020;2020:1594726
BioMed research international 2020;2020:1594726
HuR Affects Proliferation and Apoptosis of Chronic Lymphocytic Leukemia Cells via NF-κB Pathway.
Xiao K, Yang L, Gao X, An Y, Xie W, Jingquan G
BioMed research international 2020;2020:1481572
BioMed research international 2020;2020:1481572
Azelaic Acid Exerts Antileukemia Effects against Acute Myeloid Leukemia by Regulating the Prdxs/ROS Signaling Pathway.
Zhang D, Luo Z, Jin Y, Chen Y, Yang T, Yang Q, Wu B, Shang Y, Liu X, Wei Y, Zhou F
Oxidative medicine and cellular longevity 2020;2020:1295984
Oxidative medicine and cellular longevity 2020;2020:1295984
Melatonin Alleviates Neuroinflammation and Metabolic Disorder in DSS-Induced Depression Rats.
Lv WJ, Liu C, Yu LZ, Zhou JH, Li Y, Xiong Y, Guo A, Chao LM, Qu Q, Wei GW, Tang XG, Yin YL, Guo SN
Oxidative medicine and cellular longevity 2020;2020:1241894
Oxidative medicine and cellular longevity 2020;2020:1241894
Suppression of NLRP3 Inflammasome, Pyroptosis, and Cell Death by NIM811 in Rotenone-Exposed Cells as an in vitro Model of Parkinson's Disease.
Zhang M, He Q, Chen G, Li PA
Neuro-degenerative diseases 2020;20(2-3):73-83
Neuro-degenerative diseases 2020;20(2-3):73-83
MiR-1307-5p targeting TRAF3 upregulates the MAPK/NF-κB pathway and promotes lung adenocarcinoma proliferation.
Du X, Wang S, Liu X, He T, Lin X, Wu S, Wang D, Li J, Huang W, Yang H
Cancer cell international 2020;20:502
Cancer cell international 2020;20:502
XIST lost induces ovarian cancer stem cells to acquire taxol resistance via a KMT2C-dependent way.
Huang R, Zhu L, Zhang Y
Cancer cell international 2020;20:436
Cancer cell international 2020;20:436
TET1 promotes fatty acid oxidation and inhibits NAFLD progression by hydroxymethylation of PPARα promoter.
Wang J, Zhang Y, Zhuo Q, Tseng Y, Wang J, Ma Y, Zhang J, Liu J
Nutrition & metabolism 2020;17:46
Nutrition & metabolism 2020;17:46
Integrin α1 promotes tumorigenicity and progressive capacity of colorectal cancer.
Li H, Wang Y, Rong SK, Li L, Chen T, Fan YY, Wang YF, Yang CR, Yang C, Cho WC, Yang J
International journal of biological sciences 2020;16(5):815-826
International journal of biological sciences 2020;16(5):815-826
PFKP is transcriptionally repressed by BRCA1/ZBRK1 and predicts prognosis in breast cancer.
Yeerken D, Hong R, Wang Y, Gong Y, Liu R, Yang D, Li J, Fan J, Chen J, Zhang W, Zhan Q
PloS one 2020;15(5):e0233750
PloS one 2020;15(5):e0233750
Structure-function analyses of candidate small molecule RPN13 inhibitors with antitumor properties.
Anchoori RK, Tan M, Tseng SH, Peng S, Soong RS, Algethami A, Foran P, Das S, Wang C, Wang TL, Liang H, Hung CF, Roden RBS
PloS one 2020;15(1):e0227727
PloS one 2020;15(1):e0227727
Jia-Ji Electro-Acupuncture Improves Locomotor Function With Spinal Cord Injury by Regulation of Autophagy Flux and Inhibition of Necroptosis.
Hongna Y, Hongzhao T, Quan L, Delin F, Guijun L, Xiaolin L, Fulin G, Zhongren S
Frontiers in neuroscience 2020;14:616864
Frontiers in neuroscience 2020;14:616864
Hydrogen Sulfide Overproduction Is Involved in Acute Ischemic Cerebral Injury Under Hyperhomocysteinemia.
Ji Y, Li Y, Zhao Z, Li P, Xie Y
Frontiers in neuroscience 2020;14:582851
Frontiers in neuroscience 2020;14:582851
Olfactory Mucosa Mesenchymal Stem Cells Ameliorate Cerebral Ischemic/Reperfusion Injury Through Modulation of UBIAD1 Expression.
Liu J, Huang Y, He J, Zhuo Y, Chen W, Ge L, Duan D, Lu M, Hu Z
Frontiers in cellular neuroscience 2020;14:580206
Frontiers in cellular neuroscience 2020;14:580206
Differences in DNA Methylation Reprogramming Underlie the Sexual Dimorphism of Behavioral Disorder Caused by Prenatal Stress in Rats.
Lei L, Wu X, Gu H, Ji M, Yang J
Frontiers in neuroscience 2020;14:573107
Frontiers in neuroscience 2020;14:573107
iTRAQ-Based Quantitative Proteomic Analysis of Intestines in Murine Polymicrobial Sepsis with Hydrogen Gas Treatment.
Jiang Y, Bian Y, Lian N, Wang Y, Xie K, Qin C, Yu Y
Drug design, development and therapy 2020;14:4885-4900
Drug design, development and therapy 2020;14:4885-4900
Identification of a Novel c-Myc Inhibitor 7594-0037 by Structure-Based Virtual Screening and Investigation of Its Anti-Cancer Effect on Multiple Myeloma.
Yao R, Xie Y, Sun X, Zhang M, Zhou J, Liu L, Gao J, Xu K
Drug design, development and therapy 2020;14:3983-3993
Drug design, development and therapy 2020;14:3983-3993
The Potential Effects of Aliskiren on Atrial Remodeling Induced by Chronic Intermittent Hypoxia in Rats.
Miao S, Yang Y, Li R, Yin L, Zhang K, Cheng L, Xu X, Wang W, Zhao Z, Li G
Drug design, development and therapy 2020;14:3755-3764
Drug design, development and therapy 2020;14:3755-3764
Electro-Acupuncture Promotes the Differentiation of Endogenous Neural Stem Cells via Exosomal microRNA 146b After Ischemic Stroke.
Zhang S, Jin T, Wang L, Liu W, Zhang Y, Zheng Y, Lin Y, Yang M, He X, Lin H, Chen L, Tao J
Frontiers in cellular neuroscience 2020;14:223
Frontiers in cellular neuroscience 2020;14:223
Paeoniflorin Ameliorates Chronic Hypoxia/SU5416-Induced Pulmonary Arterial Hypertension by Inhibiting Endothelial-to-Mesenchymal Transition.
Yu M, Peng L, Liu P, Yang M, Zhou H, Ding Y, Wang J, Huang W, Tan Q, Wang Y, Xie W, Kong H, Wang H
Drug design, development and therapy 2020;14:1191-1202
Drug design, development and therapy 2020;14:1191-1202
The knockdown of the sepiapterin reductase gene suppresses the proliferation of breast cancer by inducing ROS-mediated apoptosis.
Zhang X, Chen Y, Wang K, Tang J, Chen Y, Jin G, Liu X
International journal of clinical and experimental pathology 2020;13(9):2228-2239
International journal of clinical and experimental pathology 2020;13(9):2228-2239
Chaetomugilin J Enhances Apoptosis in Human Ovarian Cancer A2780 Cells Induced by Cisplatin Through Inhibiting Pink1/Parkin Mediated Mitophagy.
Hu X, Wang J, Chai J, Yu X, Zhang Y, Feng Y, Qin J, Yu H
OncoTargets and therapy 2020;13:9967-9976
OncoTargets and therapy 2020;13:9967-9976
MicroRNA-623 Inhibits Epithelial-Mesenchymal Transition to Attenuate Glioma Proliferation by Targeting TRIM44.
Cui D, Wang K, Liu Y, Gao J, Cui J
OncoTargets and therapy 2020;13:9291-9303
OncoTargets and therapy 2020;13:9291-9303
Excessive Treadmill Training Enhances Brain-Specific MicroRNA-34a in the Mouse Hippocampus.
Xu L, Zheng YL, Yin X, Xu SJ, Tian D, Zhang CY, Wang S, Ma JZ
Frontiers in molecular neuroscience 2020;13:7
Frontiers in molecular neuroscience 2020;13:7
Chronic Intermittent Hypobaric Hypoxia Restores Hippocampus Function and Rescues Cognitive Impairments in Chronic Epileptic Rats via Wnt/β-catenin Signaling.
Sun C, Fu J, Qu Z, Jia L, Li D, Zhen J, Wang W
Frontiers in molecular neuroscience 2020;13:617143
Frontiers in molecular neuroscience 2020;13:617143
β-Elemene Enhances the Chemotherapeutic Effect of 5-Fluorouracil in Triple-Negative Breast Cancer via PI3K/AKT, RAF-MEK-ErK, and NF-κB Signaling Pathways.
Su P, Ahmad B, Zou K, Zou L
OncoTargets and therapy 2020;13:5207-5222
OncoTargets and therapy 2020;13:5207-5222
Elevated Levels of circRUNX1 in Colorectal Cancer Promote Cell Growth and Metastasis via miR-145-5p/IGF1 Signalling.
Chen ZL, Li XN, Ye CX, Chen HY, Wang ZJ
OncoTargets and therapy 2020;13:4035-4048
OncoTargets and therapy 2020;13:4035-4048
Microsatellite Instability-Related ACVR2A Mutations Partially Account for Decreased Lymph Node Metastasis in MSI-H Gastric Cancers.
Zhao L, Zhang J, Qu X, Yang Y, Gong Z, Yang Y, Wu Z, Guo W
OncoTargets and therapy 2020;13:3809-3821
OncoTargets and therapy 2020;13:3809-3821
Long Noncoding RNA NEAT1 Upregulates Survivin and Facilitates Gallbladder Cancer Progression by Sponging microRNA-335.
Yang F, Tang Z, Duan A, Yi B, Shen N, Bo Z, Yin L, Zhu B, Qiu Y, Li J
OncoTargets and therapy 2020;13:2357-2367
OncoTargets and therapy 2020;13:2357-2367
Alpha1-Antitrypsin in Urinary Extracellular Vesicles: A Potential Biomarker of Diabetic Kidney Disease Prior to Microalbuminuria.
Ning J, Xiang Z, Xiong C, Zhou Q, Wang X, Zou H
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:2037-2048
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:2037-2048
Empagliflozin Protects Against Proximal Renal Tubular Cell Injury Induced by High Glucose via Regulation of Hypoxia-Inducible Factor 1-Alpha.
Ndibalema AR, Kabuye D, Wen S, Li L, Li X, Fan Q
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:1953-1967
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:1953-1967
Simultaneous Inhibition of Ornithine Decarboxylase 1 and Pyruvate Kinase M2 Exerts Synergistic Effects Against Hepatocellular Carcinoma Cells.
Zeng Z, Lan J, Lei S, Yang Y, He Z, Xue Y, Chen T
OncoTargets and therapy 2020;13:11697-11709
OncoTargets and therapy 2020;13:11697-11709
MiR-935/HIF1α Feedback Loop Inhibits the Proliferation and Invasiveness of Glioma.
Huang G, Chen J, Liu J, Zhang X, Duan H, Fang Q
OncoTargets and therapy 2020;13:10817-10828
OncoTargets and therapy 2020;13:10817-10828
SNHG9 was upregulated in NSCLC and associated with DDP-resistance and poor prognosis of NSCLC patients.
Wang R, Chen C, Kang W, Meng G
American journal of translational research 2020;12(8):4456-4466
American journal of translational research 2020;12(8):4456-4466
Brequinar inhibits enterovirus replication by targeting biosynthesis pathway of pyrimidines.
Fu H, Zhang Z, Dai Y, Liu S, Fu E
American journal of translational research 2020;12(12):8247-8255
American journal of translational research 2020;12(12):8247-8255
A New Rat Model of Chronic Cerebral Hypoperfusion Resulting in Early-Stage Vascular Cognitive Impairment.
Wang J, Yang C, Wang H, Li D, Li T, Sun Y, Zhao M, Ma J, Hua W, Yang Z
Frontiers in aging neuroscience 2020;12:86
Frontiers in aging neuroscience 2020;12:86
Overexpression of IGFBP5 Enhances Radiosensitivity Through PI3K-AKT Pathway in Prostate Cancer.
Chen X, Yu Q, Pan H, Li P, Wang X, Fu S
Cancer management and research 2020;12:5409-5418
Cancer management and research 2020;12:5409-5418
Long Noncoding RNA LINC00261 Reduces Proliferation and Migration of Breast Cancer Cells via the NME1-EMT Pathway.
Guo G, Dai S, Chen Q
Cancer management and research 2020;12:3081-3089
Cancer management and research 2020;12:3081-3089
Resatorvid Relieves Breast Cancer Complicated with Depression by Inactivating Hippocampal Microglia Through TLR4/NF-κB/NLRP3 Signaling Pathway.
Luo W, Han Y, Meng P, Yang Q, Zhao H, Ling J, Wang Y
Cancer management and research 2020;12:13003-13014
Cancer management and research 2020;12:13003-13014
The lncRNA BCYRN1 Functions as an Oncogene in Human Glioma by Downregulating miR-125a-5p in vitro.
Yu W, Xiang D, Jia H, He X, Sheng J, Long Y, Zhu S, Wang K, Liu Q
Cancer management and research 2020;12:1151-1161
Cancer management and research 2020;12:1151-1161
Pyruvate dehydrogenase kinase 1 interferes with glucose metabolism reprogramming and mitochondrial quality control to aggravate stress damage in cancer.
Deng X, Wang Q, Cheng M, Chen Y, Yan X, Guo R, Sun L, Li Y, Liu Y
Journal of Cancer 2020;11(4):962-973
Journal of Cancer 2020;11(4):962-973
Long Noncoding RNA DSCAM-AS1 Facilitates Colorectal Cancer Cell Proliferation and Migration via miR-137/Notch1 Axis.
Xu J, Wu G, Zhao Y, Han Y, Zhang S, Li C, Zhang J
Journal of Cancer 2020;11(22):6623-6632
Journal of Cancer 2020;11(22):6623-6632
Arsenic trioxide (ATO) induced degradation of Cyclin D1 sensitized PD-1/PD-L1 checkpoint inhibitor in oral and esophageal squamous cell carcinoma.
Zhu G, Li X, Li J, Zhou W, Chen Z, Fan Y, Jiang Y, Zhao Y, Sun G, Mao W
Journal of Cancer 2020;11(22):6516-6529
Journal of Cancer 2020;11(22):6516-6529
Translocator Protein 18 kDa (TSPO) Deficiency Inhibits Microglial Activation and Impairs Mitochondrial Function.
Yao R, Pan R, Shang C, Li X, Cheng J, Xu J, Li Y
Frontiers in pharmacology 2020;11:986
Frontiers in pharmacology 2020;11:986
Mitochondrial Iron Overload-Mediated Inhibition of Nrf2-HO-1/GPX4 Assisted ALI-Induced Nephrotoxicity.
Deng HF, Yue LX, Wang NN, Zhou YQ, Zhou W, Liu X, Ni YH, Huang CS, Qiu LZ, Liu H, Tan HL, Tang XL, Wang YG, Ma ZC, Gao Y
Frontiers in pharmacology 2020;11:624529
Frontiers in pharmacology 2020;11:624529
Histone Deacetylase SIRT1 Mediates C5b-9-Induced Cell Cycle in Oligodendrocytes.
Tatomir A, Rao G, Boodhoo D, Vlaicu SI, Beltrand A, Anselmo F, Rus V, Rus H
Frontiers in immunology 2020;11:619
Frontiers in immunology 2020;11:619
Oleoylethanolamide Protects Against Acute Liver Injury by Regulating Nrf-2/HO-1 and NLRP3 Pathways in Mice.
Hu J, Zhu Z, Ying H, Yao J, Ma H, Li L, Zhao Y
Frontiers in pharmacology 2020;11:605065
Frontiers in pharmacology 2020;11:605065
A Mechanism of Action Study on Danggui Sini Decoction to Discover Its Therapeutic Effect on Gastric Cancer.
Pan B, Wang Y, Wu C, Jia J, Huang C, Fang S, Liu L
Frontiers in pharmacology 2020;11:592903
Frontiers in pharmacology 2020;11:592903
JAK2(V617F) Mutation Promoted IL-6 Production and Glycolysis via Mediating PKM1 Stabilization in Macrophages.
Li R, Sun N, Chen X, Li X, Zhao J, Cheng W, Hua H, Fukatsu M, Mori H, Takahashi H, Ohkawara H, Fukami M, Okamoto M, Hamazaki Y, Zheng K, Yang J, Ikezoe T
Frontiers in immunology 2020;11:589048
Frontiers in immunology 2020;11:589048
Bu-Shen-Huo-Xue Decoction Ameliorates Diabetic Nephropathy by Inhibiting Rac1/PAK1/p38MAPK Signaling Pathway in High-Fat Diet/Streptozotocin-Induced Diabetic Mice.
Wang W, Long H, Huang W, Zhang T, Xie L, Chen C, Liu J, Xiong D, Hu W
Frontiers in pharmacology 2020;11:587663
Frontiers in pharmacology 2020;11:587663
miR-222 Suppresses Immature Porcine Sertoli Cell Growth by Targeting the GRB10 Gene Through Inactivating the PI3K/AKT Signaling Pathway.
Luo H, Peng F, Weng B, Tang X, Chen Y, Yang A, Chen B, Ran M
Frontiers in genetics 2020;11:581593
Frontiers in genetics 2020;11:581593
Bu-Yin-Qian-Zheng Formula Ameliorates MPP(+)-Induced Mitochondrial Dysfunction in Parkinson's Disease via Parkin.
Ma HJ, Gai C, Chai Y, Feng WD, Cheng CC, Zhang JK, Zhang YX, Yang LP, Guo ZY, Gao YS, Sun HM
Frontiers in pharmacology 2020;11:577017
Frontiers in pharmacology 2020;11:577017
Molecular and Immune Characteristics for Lung Adenocarcinoma Patients With ERLIN2 Overexpression.
Liu Y, Xie P, Jiang D, Liu J, Zhang J, Bian T, Shi J
Frontiers in immunology 2020;11:568440
Frontiers in immunology 2020;11:568440
microRNA-630 Regulates Underglycosylated IgA1 Production in the Tonsils by Targeting TLR4 in IgA Nephropathy.
Liu C, Ye MY, Yan WZ, Peng XF, He LY, Peng YM
Frontiers in immunology 2020;11:563699
Frontiers in immunology 2020;11:563699
Metabolomics Deciphers Potential Targets of Xuefu Zhuyu Decoction Against Traumatic Brain Injury in Rat.
Li T, Hu E, Li P, Yang Z, Wu Y, Ding R, Zhu X, Tang T, Wang Y
Frontiers in pharmacology 2020;11:559618
Frontiers in pharmacology 2020;11:559618
Susceptibility to Hyperglycemia in Rats With Stress-Induced Depressive-Like Behavior: Involvement of IL-6 Mediated Glucose Homeostasis Signaling.
Li X, Qiu W, Li N, Da X, Ma Q, Hou Y, Wang T, Song M, Chen J
Frontiers in psychiatry 2020;11:557
Frontiers in psychiatry 2020;11:557
PKM2-c-Myc-Survivin Cascade Regulates the Cell Proliferation, Migration, and Tamoxifen Resistance in Breast Cancer.
Yu P, Li AX, Chen XS, Tian M, Wang HY, Wang XL, Zhang Y, Wang KS, Cheng Y
Frontiers in pharmacology 2020;11:550469
Frontiers in pharmacology 2020;11:550469
Effects of Xiaoyaosan on Depressive-Like Behaviors in Rats With Chronic Unpredictable Mild Stress Through HPA Axis Induced Astrocytic Activities.
Song M, Zhang J, Li X, Liu Y, Wang T, Yan Z, Chen J
Frontiers in psychiatry 2020;11:545823
Frontiers in psychiatry 2020;11:545823
Lian Hua Qing Wen Capsules, a Potent Epithelial Protector in Acute Lung Injury Model, Block Proapoptotic Communication Between Macrophages, and Alveolar Epithelial Cells.
Li Q, Ran Q, Sun L, Yin J, Luo T, Liu L, Zhao Z, Yang Q, Li Y, Chen Y, Weng X, Wang Y, Cai W, Zhu X
Frontiers in pharmacology 2020;11:522729
Frontiers in pharmacology 2020;11:522729
ARP-1 Regulates the Transcriptional Activity of the Aromatase Gene in the Mouse Brain.
Honda SI, Harada N
Frontiers in endocrinology 2020;11:306
Frontiers in endocrinology 2020;11:306
Scutellarein inhibits BLM-mediated pulmonary fibrosis by affecting fibroblast differentiation, proliferation, and apoptosis.
Miao K, Pan T, Mou Y, Zhang L, Xiong W, Xu Y, Yu J, Wang Y
Therapeutic advances in chronic disease 2020;11:2040622320940185
Therapeutic advances in chronic disease 2020;11:2040622320940185
MicroRNA-34a Inhibition Alleviates Lung Injury in Cecal Ligation and Puncture Induced Septic Mice.
Chen S, Ding R, Hu Z, Yin X, Xiao F, Zhang W, Yan S, Lv C
Frontiers in immunology 2020;11:1829
Frontiers in immunology 2020;11:1829
PPARγ as an E3 Ubiquitin-Ligase Impedes Phosphate-Stat6 Stability and Promotes Prostaglandins E(2)-Mediated Inhibition of IgE Production in Asthma.
Wu J, Wang Y, Zhou Y, Wang Y, Sun X, Zhao Y, Guan Y, Zhang Y, Wang W
Frontiers in immunology 2020;11:1224
Frontiers in immunology 2020;11:1224
Schisandrin B Inhibits Osteoclastogenesis and Protects Against Ovariectomy-Induced Bone Loss.
Wang J, Fang Z, Song C, Kang H, Guo Q, Dong Y, Zhang Y, Peng R, Guan H, Li F
Frontiers in pharmacology 2020;11:1175
Frontiers in pharmacology 2020;11:1175
Toddalolactone Protects Lipopolysaccharide-Induced Sepsis and Attenuates Lipopolysaccharide-Induced Inflammatory Response by Modulating HMGB1-NF-κB Translocation.
Ni J, Zhao Y, Su J, Liu Z, Fang S, Li L, Deng J, Fan G
Frontiers in pharmacology 2020;11:109
Frontiers in pharmacology 2020;11:109
MiR-10a-5p-Mediated Syndecan 1 Suppression Restricts Porcine Hemagglutinating Encephalomyelitis Virus Replication.
Hu S, Li Z, Lan Y, Guan J, Zhao K, Chu D, Fan G, Guo Y, Gao F, He W
Frontiers in microbiology 2020;11:105
Frontiers in microbiology 2020;11:105
Eye Drops of Metformin Prevents Fibrosis After Glaucoma Filtration Surgery in Rats via Activating AMPK/Nrf2 Signaling Pathway.
Li X, Leng Y, Jiang Q, Wang Z, Luo P, Zhang C, Chen L, Wang Y, Wang H, Yue X, Shen C, Zhou Y, Shi C, Xie L
Frontiers in pharmacology 2020;11:1038
Frontiers in pharmacology 2020;11:1038
CoenzymeQ10-Induced Activation of AMPK-YAP-OPA1 Pathway Alleviates Atherosclerosis by Improving Mitochondrial Function, Inhibiting Oxidative Stress and Promoting Energy Metabolism.
Xie T, Wang C, Jin Y, Meng Q, Liu Q, Wu J, Sun H
Frontiers in pharmacology 2020;11:1034
Frontiers in pharmacology 2020;11:1034
A miR-146a-5p/TRAF6/NF-kB p65 axis regulates pancreatic cancer chemoresistance: functional validation and clinical significance.
Meng Q, Liang C, Hua J, Zhang B, Liu J, Zhang Y, Wei M, Yu X, Xu J, Shi S
Theranostics 2020;10(9):3967-3979
Theranostics 2020;10(9):3967-3979
α1,6-Fucosyltransferase (FUT8) regulates the cancer-promoting capacity of cancer-associated fibroblasts (CAFs) by modifying EGFR core fucosylation (CF) in non-small cell lung cancer (NSCLC).
Li F, Zhao S, Cui Y, Guo T, Qiang J, Xie Q, Yu W, Guo W, Deng W, Gu C, Wu T
American journal of cancer research 2020;10(3):816-837
American journal of cancer research 2020;10(3):816-837
Cardio-renal Exosomes in Myocardial Infarction Serum Regulate Proangiogenic Paracrine Signaling in Adipose Mesenchymal Stem Cells.
Gao L, Mei S, Zhang S, Qin Q, Li H, Liao Y, Fan H, Liu Z, Zhu H
Theranostics 2020;10(3):1060-1073
Theranostics 2020;10(3):1060-1073
Theta-burst transcranial magnetic stimulation promotes stroke recovery by vascular protection and neovascularization.
Zong X, Li Y, Liu C, Qi W, Han D, Tucker L, Dong Y, Hu S, Yan X, Zhang Q
Theranostics 2020;10(26):12090-12110
Theranostics 2020;10(26):12090-12110
Graphene oxide improves postoperative cognitive dysfunction by maximally alleviating amyloid beta burden in mice.
Zhang J, Zhu S, Jin P, Huang Y, Dai Q, Zhu Q, Wei P, Yang Z, Zhang L, Liu H, Xu G, Chen L, Gu E, Zhang Y, Wen L, Liu X
Theranostics 2020;10(26):11908-11920
Theranostics 2020;10(26):11908-11920
Targeting BCL10 by small peptides for the treatment of B cell lymphoma.
Bao W, Sun C, Sun X, He M, Yu H, Yan W, Wen F, Zhang L, Yang C
Theranostics 2020;10(25):11622-11636
Theranostics 2020;10(25):11622-11636
Flubendazole elicits anti-cancer effects via targeting EVA1A-modulated autophagy and apoptosis in Triple-negative Breast Cancer.
Zhen Y, Zhao R, Wang M, Jiang X, Gao F, Fu L, Zhang L, Zhou XL
Theranostics 2020;10(18):8080-8097
Theranostics 2020;10(18):8080-8097
Protein acetylation derepresses Serotonin Synthesis to potentiate Pancreatic Beta-Cell Function through HDAC1-PKA-Tph1 signaling.
Zhang Y, Wang S, Zhang L, Zhou F, Zhu K, Zhu Q, Liu Q, Liu Y, Jiang L, Ning G, Bi Y, Zhou L, Wang X
Theranostics 2020;10(16):7351-7368
Theranostics 2020;10(16):7351-7368
Homozygous MESP1 knock-in reporter hESCs facilitated cardiovascular cell differentiation and myocardial infarction repair.
Wang L, Zhang F, Duan F, Huang R, Chen X, Ming J, Na J
Theranostics 2020;10(15):6898-6914
Theranostics 2020;10(15):6898-6914
Extracellular vesicle-mediated delivery of miR-101 inhibits lung metastasis in osteosarcoma.
Zhang K, Dong C, Chen M, Yang T, Wang X, Gao Y, Wang L, Wen Y, Chen G, Wang X, Yu X, Zhang Y, Wang P, Shang M, Han K, Zhou Y
Theranostics 2020;10(1):411-425
Theranostics 2020;10(1):411-425
Aberrant miR-1246 expression promotes radioresistance in non-small cell lung cancer: a potential prognostic biomarker and radiotherapy sensitization target.
Fan L, Wang J, Cao Q, Ding X, Li B
American journal of cancer research 2020;10(1):314-335
American journal of cancer research 2020;10(1):314-335
KLF13 suppresses the proliferation and growth of colorectal cancer cells through transcriptionally inhibiting HMGCS1-mediated cholesterol biosynthesis.
Yao W, Jiao Y, Zhou Y, Luo X
Cell & bioscience 2020;10:76
Cell & bioscience 2020;10:76
TIPE Regulates DcR3 Expression and Function by Activating the PI3K/AKT Signaling Pathway in CRC.
Zhong M, Qiu X, Liu Y, Yang Y, Gu L, Wang C, Chen H, Liu Z, Miao J, Zhuang G
Frontiers in oncology 2020;10:623048
Frontiers in oncology 2020;10:623048
Forkhead Box Q1 Is Critical to Angiogenesis and Macrophage Recruitment of Colorectal Cancer.
Tang H, Zheng J, Bai X, Yue KL, Liang JH, Li DY, Wang LP, Wang JL, Guo Q
Frontiers in oncology 2020;10:564298
Frontiers in oncology 2020;10:564298
Up-regulation of L Antigen Family Member 3 Associates With Aggressive Progression of Breast Cancer.
Dong X, Lv S, Gu D, Zhang X, Ye Z
Frontiers in oncology 2020;10:553628
Frontiers in oncology 2020;10:553628
A Natural Dietary Flavone Myricetin as an α-Hemolysin Inhibitor for Controlling Staphylococcus aureus Infection.
Wang T, Zhang P, Lv H, Deng X, Wang J
Frontiers in cellular and infection microbiology 2020;10:330
Frontiers in cellular and infection microbiology 2020;10:330
Steroid 5α-Reductase Type I Induces Cell Viability and Migration via Nuclear Factor-κB/Vascular Endothelial Growth Factor Signaling Pathway in Colorectal Cancer.
Wei R, Zhong S, Qiao L, Guo M, Shao M, Wang S, Jiang B, Yang Y, Gu C
Frontiers in oncology 2020;10:1501
Frontiers in oncology 2020;10:1501
The SIRT6-Autophagy-Warburg Effect Axis in Papillary Thyroid Cancer.
Yang Z, Huang R, Wei X, Yu W, Min Z, Ye M
Frontiers in oncology 2020;10:1265
Frontiers in oncology 2020;10:1265
Methylation-Induced Silencing of ALDH2 Facilitates Lung Adenocarcinoma Bone Metastasis by Activating the MAPK Pathway.
Yang M, Wang A, Li C, Sun J, Yi G, Cheng H, Liu X, Wang Z, Zhou Y, Yao G, Wang S, Liang R, Li B, Li D, Zhao H
Frontiers in oncology 2020;10:1141
Frontiers in oncology 2020;10:1141
Prognostic and Clinicopathological Significance of X-Box-Binding Protein 1 and N-Acetyltransferase 1 in Gallbladder Cancer.
Liu R, Wu Z, Zhang Y, Miao X, Zou Q, Yuan Y, Li D, Yang Z
Frontiers in oncology 2020;10:1124
Frontiers in oncology 2020;10:1124
NLRP6 contributes to inflammation and brain injury following intracerebral haemorrhage by activating autophagy.
Xiao H, Chen H, Jiang R, Zhang L, Wang L, Gan H, Jiang N, Zhao J, Zhai X, Liang P
Journal of molecular medicine (Berlin, Germany) 2020 Sep;98(9):1319-1331
Journal of molecular medicine (Berlin, Germany) 2020 Sep;98(9):1319-1331
Low-dose naltrexone inhibits the epithelial-mesenchymal transition of cervical cancer cells in vitro and effects indirectly on tumor-associated macrophages in vivo.
Liu N, Ma M, Qu N, Wang R, Chen H, Hu F, Gao S, Shan F
International immunopharmacology 2020 Sep;86:106718
International immunopharmacology 2020 Sep;86:106718
Increased regulatory T cells and eosinophils characterize atopic dermatitis-like graft-versus-host disease compared with lichen planus-like graft-versus-host disease.
Li K, Mu Z, Wen G, Zhao Y, Cong X, Zhang J
Journal of the American Academy of Dermatology 2020 Sep;83(3):824-831
Journal of the American Academy of Dermatology 2020 Sep;83(3):824-831
Sublethal Levels of Antibiotics Promote Bacterial Persistence in Epithelial Cells.
Liu X, Liu F, Ding S, Shen J, Zhu K
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2020 Sep;7(18):1900840
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2020 Sep;7(18):1900840
Mitochondrial Transplantation Attenuates Brain Dysfunction in Sepsis by Driving Microglial M2 Polarization.
Yan C, Ma Z, Ma H, Li Q, Zhai Q, Jiang T, Zhang Z, Wang Q
Molecular neurobiology 2020 Sep;57(9):3875-3890
Molecular neurobiology 2020 Sep;57(9):3875-3890
S-palmitoylation of swine interferon-inducible transmembrane protein is essential for its anti-JEV activity.
Xu Z, Li X, Xue J, Shen L, Zheng W, Yin S, Xu J
Virology 2020 Sep;548:82-92
Virology 2020 Sep;548:82-92
Deficiency of Grx1 leads to high sensitivity of HeLaS3 cells to oxidative stress via excessive accumulation of intracellular oxidants including ROS.
Zhao T, Zhang-Akiyama QM
Free radical research 2020 Sep;54(8-9):585-605
Free radical research 2020 Sep;54(8-9):585-605
Estrogen Exerts Neuroprotective Effects in Vascular Dementia Rats by Suppressing Autophagy and Activating the Wnt/β-Catenin Signaling Pathway.
Yang Y, Zhao L, Li N, Dai C, Yin N, Chu Z, Duan X, Niu X, Yan P, Lv P
Neurochemical research 2020 Sep;45(9):2100-2112
Neurochemical research 2020 Sep;45(9):2100-2112
MCC950 Inhibits NLRP3 Inflammasome and Alleviates Axonal Injures in Early Stages of Diffuse Axonal Injury in Rats.
Zhao J, Guo X, Wang B, Yang Z, Huang T, Guo D, Zhang M, Song J
Neurochemical research 2020 Sep;45(9):2020-2031
Neurochemical research 2020 Sep;45(9):2020-2031
A novel GNAS-mutated human induced pluripotent stem cell model for understanding GNAS-mutated tumors.
Watanabe K, Nakamura T, Onodera S, Saito A, Shibahara T, Azuma T
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2020 Sep;42(9):1010428320962588
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2020 Sep;42(9):1010428320962588
Visualization of translocator protein (18 kDa) (TSPO) in the retina of diabetic retinopathy rats using fluorine-18-DPA-714.
Zhou Y, Ou Y, Ju Z, Zhang X, Zheng L, Li J, Sun Y, Liu X
Annals of nuclear medicine 2020 Sep;34(9):675-681
Annals of nuclear medicine 2020 Sep;34(9):675-681
SRSF10 inhibits the polymerase activity and replication of avian influenza virus by regulating the alternative splicing of chicken ANP32A.
Fang A, Bi Z, Ye H, Yan L
Virus research 2020 Sep;286:198063
Virus research 2020 Sep;286:198063
The deubiquitylase USP2 maintains ErbB2 abundance via counteracting endocytic degradation and represents a therapeutic target in ErbB2-positive breast cancer.
Zhang J, Liu S, Li Q, Shi Y, Wu Y, Liu F, Wang S, Zaky MY, Yousuf W, Sun Q, Guo D, Wang T, Zhang Y, Wang Y, Li M, Liu H
Cell death and differentiation 2020 Sep;27(9):2710-2725
Cell death and differentiation 2020 Sep;27(9):2710-2725
RUNX3-dependent oxidative epithelial-to-mesenchymal transition in methamphetamine-induced chronic lung injury.
Shi L, Liu BY, Wang X, Zhu MJ, Chen L, Zhou MY, Gu YJ, Cheng L, Wang Y
Cell stress & chaperones 2020 Sep;25(5):793-802
Cell stress & chaperones 2020 Sep;25(5):793-802
ACE2 modulates glucose homeostasis through GABA signaling during metabolic stress.
Ma X, Gao F, Chen Q, Xuan X, Wang Y, Deng H, Yang F, Yuan L
The Journal of endocrinology 2020 Sep;246(3):223-236
The Journal of endocrinology 2020 Sep;246(3):223-236
Musashi2 promotes the progression of pancreatic cancer through a novel ISYNA1-p21/ZEB-1 pathway.
Zhou L, Sheng W, Jia C, Shi X, Cao R, Wang G, Lin Y, Zhu F, Dong Q, Dong M
Journal of cellular and molecular medicine 2020 Sep;24(18):10560-10572
Journal of cellular and molecular medicine 2020 Sep;24(18):10560-10572
Tacrolimus ameliorates tubulointerstitial inflammation in diabetic nephropathy via inhibiting the NFATc1/TRPC6 pathway.
Zhang S, Wang H, Liu Y, Yang W, Liu J, Han Y, Liu Y, Liu F, Sun L, Xiao L
Journal of cellular and molecular medicine 2020 Sep;24(17):9810-9824
Journal of cellular and molecular medicine 2020 Sep;24(17):9810-9824
Knockdown of endogenous RNF4 exacerbates ischaemia-induced cardiomyocyte apoptosis in mice.
Qiu F, Han Y, Shao X, Paulo P, Li W, Zhu M, Tang N, Guo S, Chen Y, Wu H, Zhao D, Liu Y, Chu W
Journal of cellular and molecular medicine 2020 Sep;24(17):9545-9559
Journal of cellular and molecular medicine 2020 Sep;24(17):9545-9559
Rosamultin Attenuates Acute Hypobaric Hypoxia-Induced Bone Injuries by Regulation of Sclerostin and Its Downstream Signals.
Wang XM, Liu H, Li JY, Wei JX, Li X, Zhang YL, Li LZ, Zhang XZ
High altitude medicine & biology 2020 Sep;21(3):273-286
High altitude medicine & biology 2020 Sep;21(3):273-286
Polyphyllin II inhibits human bladder cancer migration and invasion by regulating EMT-associated factors and MMPs.
Niu W, Xu L, Li J, Zhai Y, Sun Z, Shi W, Jiang Y, Ma C, Lin H, Guo Y, Liu Z
Oncology letters 2020 Sep;20(3):2928-2936
Oncology letters 2020 Sep;20(3):2928-2936
Sirtuin 3-mediated deacetylation of acyl-CoA synthetase family member 3 by protocatechuic acid attenuates non-alcoholic fatty liver disease.
Sun R, Kang X, Zhao Y, Wang Z, Wang R, Fu R, Li Y, Hu Y, Wang Z, Shan W, Zhou J, Tian X, Yao J
British journal of pharmacology 2020 Sep;177(18):4166-4180
British journal of pharmacology 2020 Sep;177(18):4166-4180
Methamphetamine induces GSDME-dependent cell death in hippocampal neuronal cells through the endoplasmic reticulum stress pathway.
Liu Y, Wen D, Gao J, Xie B, Yu H, Shen Q, Zhang J, Jing W, Cong B, Ma C
Brain research bulletin 2020 Sep;162:73-83
Brain research bulletin 2020 Sep;162:73-83
Inhibition of NK1R attenuates LPS-induced microglial inflammation and consequent death of PC12 cells.
Jiang W, Wang X, Wang W, Hua F, Zhang Z, Zhang Z, Xiang J, Yang X
Brain research bulletin 2020 Sep;162:115-124
Brain research bulletin 2020 Sep;162:115-124
NS5-V372A and NS5-H386Y variations are responsible for differences in interferon α/β induction and co-contribute to the replication advantage of Japanese encephalitis virus genotype I over genotype III in ducklings.
Li C, Di D, Huang H, Wang X, Xia Q, Ma X, Liu K, Li B, Shao D, Qiu Y, Li Z, Wei J, Ma Z
PLoS pathogens 2020 Sep;16(9):e1008773
PLoS pathogens 2020 Sep;16(9):e1008773
H63D variant of the homeostatic iron regulator (HFE) gene alters α-synuclein expression, aggregation, and toxicity.
Kim Y, Stahl MC, Huang X, Connor JR
Journal of neurochemistry 2020 Sep;155(2):177-190
Journal of neurochemistry 2020 Sep;155(2):177-190
Interleukin-18 levels in the hippocampus and behavior of adult rat offspring exposed to prenatal restraint stress during early and late pregnancy.
Chen MX, Liu Q, Cheng S, Lei L, Lin AJ, Wei R, K Hui TC, Li Q, Ao LJ, Sham PC
Neural regeneration research 2020 Sep;15(9):1748-1756
Neural regeneration research 2020 Sep;15(9):1748-1756
Control the fate of human umbilical cord mesenchymal stem cells with dual-enzymatically cross-linked gelatin hydrogels for potential applications in nerve regeneration.
Li J, Gao F, Ma S, Zhang Y, Zhang J, Guan F, Yao M
Journal of tissue engineering and regenerative medicine 2020 Sep;14(9):1261-1271
Journal of tissue engineering and regenerative medicine 2020 Sep;14(9):1261-1271
Duck IFIT5 differentially regulates Tembusu virus replication and inhibits virus-triggered innate immune response.
Wu X, Liu K, Jia R, Pan Y, Wang M, Chen S, Liu M, Zhu D, Zhao X, Wu Y, Yang Q, Zhang S, Huang J, Zhang L, Liu Y, Tian B, Pan L, Yu Y, Ur Rehman M, Yin Z, Jing B, Cheng A
Cytokine 2020 Sep;133:155161
Cytokine 2020 Sep;133:155161
The effect of monotropein on alleviating cisplatin-induced acute kidney injury by inhibiting oxidative damage, inflammation and apoptosis.
Zhang Y, Chen Y, Li B, Ding P, Jin D, Hou S, Cai X, Sheng X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110408
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110408
Dual PI3K/mTOR inhibitor PKI-402 suppresses the growth of ovarian cancer cells by degradation of Mcl-1 through autophagy.
Hu X, Xia M, Wang J, Yu H, Chai J, Zhang Z, Sun Y, Su J, Sun L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110397
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110397
SOCS3-deficient lung epithelial cells uptaking neutrophil-derived SOCS3 worsens lung influenza infection.
Li L, Wu H, Li Q, Chen J, Xu K, Xu J, Su X
Molecular immunology 2020 Sep;125:51-62
Molecular immunology 2020 Sep;125:51-62
The roles of grouper TANK in innate immune defense against iridovirus and nodavirus infections.
Wei J, Li C, Ou J, Zhang X, Liu Z, Qin Q
Fish & shellfish immunology 2020 Sep;104:506-516
Fish & shellfish immunology 2020 Sep;104:506-516
Zinc exerts its renal protection effect on arsenic-exposed common carp: A signaling network comprising Nrf2, NF-κB and MAPK pathways.
Wang Y, Zhao H, Liu Y, Nie X, Xing M
Fish & shellfish immunology 2020 Sep;104:383-390
Fish & shellfish immunology 2020 Sep;104:383-390
S-allyl-L-cysteine protects hepatocytes from indomethacin-induced apoptosis by attenuating endoplasmic reticulum stress.
Chen P, Chen C, Hu M, Cui R, Liu F, Yu H, Ren Y
FEBS open bio 2020 Sep;10(9):1900-1911
FEBS open bio 2020 Sep;10(9):1900-1911
HEATR1 promotes proliferation in gastric cancer in vitro and in vivo.
Zhao J, Zhu Y, Fu Q, Zhu Y, Zhao G
Acta biochimica et biophysica Sinica 2020 Sep 8;52(9):1030-1039
Acta biochimica et biophysica Sinica 2020 Sep 8;52(9):1030-1039
Autocrine INSL5 promotes tumor progression and glycolysis via activation of STAT5 signaling.
Li SB, Liu YY, Yuan L, Ji MF, Zhang A, Li HY, Tang LQ, Fang SG, Zhang H, Xing S, Li MZ, Zhong Q, Lin SJ, Liu WL, Huang P, Zeng YX, Zheng YM, Ling ZQ, Sui JH, Zeng MS
EMBO molecular medicine 2020 Sep 7;12(9):e12050
EMBO molecular medicine 2020 Sep 7;12(9):e12050
Circular RNA circREPS2 Acts as a Sponge of miR-558 to Suppress Gastric Cancer Progression by Regulating RUNX3/β-catenin Signaling.
Guo X, Dai X, Liu J, Cheng A, Qin C, Wang Z
Molecular therapy. Nucleic acids 2020 Sep 4;21:577-591
Molecular therapy. Nucleic acids 2020 Sep 4;21:577-591
The microRNA/TET3/REST axis is required for olfactory globose basal cell proliferation and male behavior.
Yang D, Wu X, Zhou Y, Wang W, Wang Z
EMBO reports 2020 Sep 3;21(9):e49431
EMBO reports 2020 Sep 3;21(9):e49431
Oxidative stress mediates the apoptosis and epigenetic modification of the Bcl-2 promoter via DNMT1 in a cigarette smoke-induced emphysema model.
Zeng H, Li T, He X, Cai S, Luo H, Chen P, Chen Y
Respiratory research 2020 Sep 3;21(1):229
Respiratory research 2020 Sep 3;21(1):229
Myricanol 5-fluorobenzyloxy ether regulation of survivin pathway inhibits human lung adenocarcinoma A549 cells growth in vitro.
Dai GH, Chen X, Ren ZM, Dai CJ, Tong YL, Chai KQ
BMC complementary medicine and therapies 2020 Sep 3;20(1):269
BMC complementary medicine and therapies 2020 Sep 3;20(1):269
Characterization of Low Molecular Weight Sulfate Ulva Polysaccharide and its Protective Effect against IBD in Mice.
Li Y, Ye H, Wang T, Wang P, Liu R, Li Y, Tian Y, Zhang J
Marine drugs 2020 Sep 29;18(10)
Marine drugs 2020 Sep 29;18(10)
NOD2/c-Jun NH(2)-Terminal Kinase Triggers Mycoplasma ovipneumoniae-Induced Macrophage Autophagy.
Luo H, Wu X, Xu Z, Hao X, Wang Y, Li M
Journal of bacteriology 2020 Sep 23;202(20)
Journal of bacteriology 2020 Sep 23;202(20)
L-Theanine affects intestinal mucosal immunity by regulating short-chain fatty acid metabolism under dietary fiber feeding.
Xu W, Lin L, Liu A, Zhang T, Zhang S, Li Y, Chen J, Gong Z, Liu Z, Xiao W
Food & function 2020 Sep 23;11(9):8369-8379
Food & function 2020 Sep 23;11(9):8369-8379
Astaxanthin attenuates oxidative stress and immune impairment in D-galactose-induced aging in rats by activating the Nrf2/Keap1 pathway and suppressing the NF-κB pathway.
Chen Z, Xiao J, Liu H, Yao K, Hou X, Cao Y, Liu X
Food & function 2020 Sep 23;11(9):8099-8111
Food & function 2020 Sep 23;11(9):8099-8111
Neural progenitor cell pyroptosis contributes to Zika virus-induced brain atrophy and represents a therapeutic target.
He Z, An S, Chen J, Zhang S, Tan C, Yu J, Ye H, Wu Y, Yuan J, Wu J, Zhu X, Li M
Proceedings of the National Academy of Sciences of the United States of America 2020 Sep 22;117(38):23869-23878
Proceedings of the National Academy of Sciences of the United States of America 2020 Sep 22;117(38):23869-23878
(+)-Clausenamide protects against drug-induced liver injury by inhibiting hepatocyte ferroptosis.
Wang M, Liu CY, Wang T, Yu HM, Ouyang SH, Wu YP, Gong HB, Ma XH, Jiao GL, Fu LL, Wu QS, Kurihara H, Li YF, Shen T, He RR
Cell death & disease 2020 Sep 19;11(9):781
Cell death & disease 2020 Sep 19;11(9):781
Overexpression of MicroRNA-9a-5p Ameliorates NLRP1 Inflammasome-mediated Ischemic Injury in Rats Following Ischemic Stroke.
Cao Y, Zhang H, Lu X, Wang J, Zhang X, Sun S, Bao Z, Tian W, Ning S, Wang L, Cui L
Neuroscience 2020 Sep 15;444:106-117
Neuroscience 2020 Sep 15;444:106-117
Inhibition of autophagy enhances timosaponin AIII-induced lung cancer cell apoptosis and anti-tumor effect in vitro and in vivo.
Liu J, Deng X, Sun X, Dong J, Huang J
Life sciences 2020 Sep 15;257:118040
Life sciences 2020 Sep 15;257:118040
Inflammasome/NF-κB translocation inhibition via PPARγ agonist mitigates inorganic mercury induced nephrotoxicity.
Li S, Shi M, Wan Y, Wang Y, Zhu M, Wang B, Zhan Y, Ran B, Wu C
Ecotoxicology and environmental safety 2020 Sep 15;201:110801
Ecotoxicology and environmental safety 2020 Sep 15;201:110801
FUT9-Driven Programming of Colon Cancer Cells towards a Stem Cell-Like State.
Blanas A, Zaal A, van der Haar Àvila I, Kempers M, Kruijssen L, de Kok M, Popovic MA, van der Horst JC, J van Vliet S
Cancers 2020 Sep 10;12(9)
Cancers 2020 Sep 10;12(9)
Adenovirus-mediated specific tumor tagging facilitates CAR-T therapy against antigen-mismatched solid tumors.
Tang X, Li Y, Ma J, Wang X, Zhao W, Hossain MA, Yang Y
Cancer letters 2020 Sep 1;487:1-9
Cancer letters 2020 Sep 1;487:1-9
The AKT/GSK3-Mediated Slug Expression Contributes to Oxaliplatin Resistance in Colorectal Cancer via Upregulation of ERCC1.
Wei W, Ma XD, Jiang GM, Shi B, Zhong W, Sun CL, Zhao L, Hou YJ, Wang H
Oncology research 2020 Sep 1;28(4):423-438
Oncology research 2020 Sep 1;28(4):423-438
Combination of luteolin and lycopene effectively protect against the "two-hit" in NAFLD through Sirt1/AMPK signal pathway.
Zhu Y, Liu R, Shen Z, Cai G
Life sciences 2020 Sep 1;256:117990
Life sciences 2020 Sep 1;256:117990
Four active monomers from Moutan Cortex exert inhibitory effects against oxidative stress by activating Nrf2/Keap1 signaling pathway.
Zhang B, Yu D, Luo N, Yang C, Zhu Y
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2020 Sep 1;24(5):373-384
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2020 Sep 1;24(5):373-384
Herpes Simplex Virus Type 2 Inhibits Type I IFN Signaling Mediated by the Novel E3 Ubiquitin Protein Ligase Activity of Viral Protein ICP22.
Zhang M, Fu M, Li M, Hu H, Gong S, Hu Q
Journal of immunology (Baltimore, Md. : 1950) 2020 Sep 1;205(5):1281-1292
Journal of immunology (Baltimore, Md. : 1950) 2020 Sep 1;205(5):1281-1292
Targeting SLC7A11 specifically suppresses the progression of colorectal cancer stem cells via inducing ferroptosis.
Xu X, Zhang X, Wei C, Zheng D, Lu X, Yang Y, Luo A, Zhang K, Duan X, Wang Y
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2020 Sep 1;152:105450
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2020 Sep 1;152:105450
Stimulation of endothelial progenitor cells by microRNA-31a-5p to induce endothelialization in an aneurysm neck after coil embolization by modulating the Axin1-mediated β-catenin/vascular endothelial growth factor pathway.
Yu G, Liu P, Shi Y, Li S, Liu Y, Fan Z, Zhu W
Journal of neurosurgery 2020 Sep 1;133(3):918-926
Journal of neurosurgery 2020 Sep 1;133(3):918-926
Expression Level of Small Envelope Protein in Addition to Sequence Divergence inside Its Major Hydrophilic Region Contributes to More Efficient Surface Antigen Secretion by Hepatitis B Virus Subgenotype D2 than Subgenotype A2.
Wang Q, Fu S, Zhang J, Yuan Q, Li J, Xia N, Wen YM, Wang Y, Tong S
Viruses 2020 Sep 1;12(9)
Viruses 2020 Sep 1;12(9)
Down-regulation of NTSR3 inhibits cell growth and metastasis, as well as the PI3K-AKT and MAPK signaling pathways in colorectal cancer.
Liu A, Zuo Z, Liu L, Liu L
Biochemistry and cell biology = Biochimie et biologie cellulaire 2020 Oct;98(5):548-555
Biochemistry and cell biology = Biochimie et biologie cellulaire 2020 Oct;98(5):548-555
Cytotoxic effects of vitamins K1, K2, and K3 against human T lymphoblastoid leukemia cells through apoptosis induction and cell cycle arrest.
Xu W, Wu H, Chen S, Wang X, Tanaka S, Sugiyama K, Yamada H, Hirano T
Chemical biology & drug design 2020 Oct;96(4):1134-1147
Chemical biology & drug design 2020 Oct;96(4):1134-1147
Ubiquitin specific protease 5 negatively regulates the IFNs-mediated antiviral activity via targeting SMURF1.
Qian G, Zhu L, Huang C, Liu Y, Ren Y, Ding Y, Qian W, Xu Q, Zheng H, Lv H
International immunopharmacology 2020 Oct;87:106763
International immunopharmacology 2020 Oct;87:106763
Lycopene protects neuroblastoma cells against oxidative damage via depression of ER stress.
Ou S, Fang Y, Tang H, Wu T, Chen L, Jiang M, Zhou L, Xu J, Guo K
Journal of food science 2020 Oct;85(10):3552-3561
Journal of food science 2020 Oct;85(10):3552-3561
Upregulation of secreted phosphoprotein 1 affects malignant progression, prognosis, and resistance to cetuximab via the KRAS/MEK pathway in head and neck cancer.
Liu K, Hu H, Jiang H, Liu C, Zhang H, Gong S, Wei D, Yu Z
Molecular carcinogenesis 2020 Oct;59(10):1147-1158
Molecular carcinogenesis 2020 Oct;59(10):1147-1158
Resveratrol modulates the apoptosis and autophagic death of human lung adenocarcinoma A549 cells via a p53‑dependent pathway: Integrated bioinformatics analysis and experimental validation.
Fan Y, Li J, Yang Y, Zhao X, Liu Y, Jiang Y, Zhou L, Feng Y, Yu Y, Cheng Y
International journal of oncology 2020 Oct;57(4):925-938
International journal of oncology 2020 Oct;57(4):925-938
Schisandrin A restrains osteoclastogenesis by inhibiting reactive oxygen species and activating Nrf2 signalling.
Ni S, Qian Z, Yuan Y, Li D, Zhong Z, Ghorbani F, Zhang X, Zhang F, Zhang Z, Liu Z, Yu B
Cell proliferation 2020 Oct;53(10):e12882
Cell proliferation 2020 Oct;53(10):e12882
YY1-mediated PTEN dephosphorylation antagonizes IR-induced DNA repair contributing to tongue squamous cell carcinoma radiosensitization.
Zhao L, Li R, Qiu JZ, Yu JB, Cao Y, Yuan RT
Molecular and cellular probes 2020 Oct;53:101577
Molecular and cellular probes 2020 Oct;53:101577
Spatiotemporal expression of neurogenic locus notch homolog protein 1 in developing caudal spinal cord of fetuses with anorectal malformations from ETU-fed rats.
Yang Z, Jia H, Bai Y, Wang W
Journal of molecular histology 2020 Oct;51(5):519-530
Journal of molecular histology 2020 Oct;51(5):519-530
Silica nanoparticles induce spermatogenesis disorders via L3MBTL2-DNA damage-p53 apoptosis and RNF8-ubH2A/ubH2B pathway in mice.
Liu J, Li X, Zhou G, Sang Y, Zhang Y, Zhao Y, Ge W, Sun Z, Zhou X
Environmental pollution (Barking, Essex : 1987) 2020 Oct;265(Pt A):114974
Environmental pollution (Barking, Essex : 1987) 2020 Oct;265(Pt A):114974
Autophagy plays a protective role during Pseudomonas aeruginosa-induced apoptosis via ROS-MAPK pathway.
Han L, Ma Q, Yu J, Gong Z, Ma C, Xu Y, Deng G, Wu X
Innate immunity 2020 Oct;26(7):580-591
Innate immunity 2020 Oct;26(7):580-591
LKB1-MARK2 signalling mediates lipopolysaccharide-induced production of cytokines in mouse macrophages.
Deng J, Wen C, Ding X, Zhang X, Hou G, Liu A, Xu H, Cao X, Bai Y
Journal of cellular and molecular medicine 2020 Oct;24(19):11307-11317
Journal of cellular and molecular medicine 2020 Oct;24(19):11307-11317
Dihydrotanshinone I inhibits ovarian cancer cell proliferation and migration by transcriptional repression of PIK3CA gene.
Wang X, Xu X, Jiang G, Zhang C, Liu L, Kang J, Wang J, Owusu L, Zhou L, Zhang L, Li W
Journal of cellular and molecular medicine 2020 Oct;24(19):11177-11187
Journal of cellular and molecular medicine 2020 Oct;24(19):11177-11187
KIAA1429 regulates cell proliferation by targeting c-Jun messenger RNA directly in gastric cancer.
Miao R, Dai CC, Mei L, Xu J, Sun SW, Xing YL, Wu LS, Wang MH, Wei JF
Journal of cellular physiology 2020 Oct;235(10):7420-7432
Journal of cellular physiology 2020 Oct;235(10):7420-7432
Silencing long non‑coding RNA NEAT1 suppresses the tumorigenesis of infantile hemangioma by competitively binding miR‑33a‑5p to stimulate HIF1α/NF‑κB pathway.
Yu L, Shu H, Xing L, Lv MX, Li L, Xie YC, Zhang Z, Zhang L, Xie YY
Molecular medicine reports 2020 Oct;22(4):3358-3366
Molecular medicine reports 2020 Oct;22(4):3358-3366
Arsenic (III) and/or copper (II) induces oxidative stress in chicken brain and subsequent effects on mitochondrial homeostasis and autophagy.
Liu Y, Zhao H, Wang Y, Guo M, Mu M, Xing M
Journal of inorganic biochemistry 2020 Oct;211:111201
Journal of inorganic biochemistry 2020 Oct;211:111201
Dihydrotanshinone I inhibits human glioma cell proliferation via the activation of ferroptosis.
Tan S, Hou X, Mei L
Oncology letters 2020 Oct;20(4):122
Oncology letters 2020 Oct;20(4):122
Essential roles of S100A10 in Toll-like receptor signaling and immunity to infection.
Lou Y, Han M, Liu H, Niu Y, Liang Y, Guo J, Zhang W, Wang H
Cellular & molecular immunology 2020 Oct;17(10):1053-1062
Cellular & molecular immunology 2020 Oct;17(10):1053-1062
miR-103a-3p regulates mitophagy in Parkinson's disease through Parkin/Ambra1 signaling.
Zhou J, Zhao Y, Li Z, Zhu M, Wang Z, Li Y, Xu T, Feng D, Zhang S, Tang F, Yao J
Pharmacological research 2020 Oct;160:105197
Pharmacological research 2020 Oct;160:105197
p53 promotes ZDHHC1-mediated IFITM3 palmitoylation to inhibit Japanese encephalitis virus replication.
Wang X, Wu Z, Li Y, Yang Y, Xiao C, Liu X, Xiang X, Wei J, Shao D, Liu K, Deng X, Wu J, Qiu Y, Li B, Ma Z
PLoS pathogens 2020 Oct;16(10):e1009035
PLoS pathogens 2020 Oct;16(10):e1009035
A Histomorphological Study of the Divergent Corpus Spongiosum Surrounding the Urethral Plate in Hypospadias.
Bao X, Huang Y, Lyu Y, Xi Z, Xie H, Fu Q, Song L, Chen F
Urology 2020 Oct;144:188-193
Urology 2020 Oct;144:188-193
Exosomal miR-1255b-5p targets human telomerase reverse transcriptase in colorectal cancer cells to suppress epithelial-to-mesenchymal transition.
Zhang X, Bai J, Yin H, Long L, Zheng Z, Wang Q, Chen F, Yu X, Zhou Y
Molecular oncology 2020 Oct;14(10):2589-2608
Molecular oncology 2020 Oct;14(10):2589-2608
Polydatin alleviates parkinsonism in MPTP-model mice by enhancing glycolysis in dopaminergic neurons.
Zhang S, Wang S, Shi X, Feng X
Neurochemistry international 2020 Oct;139:104815
Neurochemistry international 2020 Oct;139:104815
Proteomic analyses reveal that Orf virus induces the activation and maturation of mouse bone marrow-derived dendritic cells.
Feng Q, Li L, Du G, Liu Y, Liu X, Wu J, Shang Y
Research in veterinary science 2020 Oct;132:563-573
Research in veterinary science 2020 Oct;132:563-573
Biomechanically reduced expression of Derlin-3 is linked to the apoptosis of chondrocytes in the mandibular condylar cartilage via the endoplasmic reticulum stress pathway.
Liu J, Yang H, Zhang H, Liu Q, Zhou P, He F, Zhang M, Yu S, Liu J, Wang M
Archives of oral biology 2020 Oct;118:104843
Archives of oral biology 2020 Oct;118:104843
T-type calcium channel blockade induces apoptosis in C2C12 myotubes and skeletal muscle via endoplasmic reticulum stress activation.
Chen M, Li S, Hao M, Chen J, Zhao Z, Hong S, Min J, Tang J, Hu M, Hong L
FEBS open bio 2020 Oct;10(10):2122-2136
FEBS open bio 2020 Oct;10(10):2122-2136
Impaired NLRP3 inflammasome activation/pyroptosis leads to robust inflammatory cell death via caspase-8/RIPK3 during coronavirus infection.
Zheng M, Williams EP, Malireddi RKS, Karki R, Banoth B, Burton A, Webby R, Channappanavar R, Jonsson CB, Kanneganti TD
The Journal of biological chemistry 2020 Oct 9;295(41):14040-14052
The Journal of biological chemistry 2020 Oct 9;295(41):14040-14052
Calreticulin promotes EMT in pancreatic cancer via mediating Ca(2+) dependent acute and chronic endoplasmic reticulum stress.
Sheng W, Wang G, Tang J, Shi X, Cao R, Sun J, Lin YH, Jia C, Chen C, Zhou J, Dong M
Journal of experimental & clinical cancer research : CR 2020 Oct 7;39(1):209
Journal of experimental & clinical cancer research : CR 2020 Oct 7;39(1):209
Profiling pro-neural to mesenchymal transition identifies a lncRNA signature in glioma.
Liang Q, Guan G, Li X, Wei C, Wu J, Cheng P, Wu A, Cheng W
Journal of translational medicine 2020 Oct 7;18(1):378
Journal of translational medicine 2020 Oct 7;18(1):378
Revealing active ingredients, potential targets, and action mechanism of Ermiao fang for treating endometritis based on network pharmacology strategy.
Zhang C, Su T, Yu D, Wang F, Yue C, Wang HQ
Journal of ethnopharmacology 2020 Oct 5;260:113051
Journal of ethnopharmacology 2020 Oct 5;260:113051
c-Myc inactivation of p53 through the pan-cancer lncRNA MILIP drives cancer pathogenesis.
Feng YC, Liu XY, Teng L, Ji Q, Wu Y, Li JM, Gao W, Zhang YY, La T, Tabatabaee H, Yan XG, Jamaluddin MFB, Zhang D, Guo ST, Scott RJ, Liu T, Thorne RF, Zhang XD, Jin L
Nature communications 2020 Oct 5;11(1):4980
Nature communications 2020 Oct 5;11(1):4980
Defect of SLC38A3 promotes epithelial-mesenchymal transition and predicts poor prognosis in esophageal squamous cell carcinoma.
Liu R, Hong R, Wang Y, Gong Y, Yeerken D, Yang D, Li J, Fan J, Chen J, Zhang W, Zhan Q
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2020 Oct 31;32(5):547-563
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2020 Oct 31;32(5):547-563
Transcriptomic and Proteomic Analysis Reveals Mechanisms of Patulin-Induced Cell Toxicity in Human Embryonic Kidney Cells.
Han N, Luo R, Liu J, Guo T, Feng J, Peng X
Toxins 2020 Oct 29;12(11)
Toxins 2020 Oct 29;12(11)
Anticancer Effects of Honokiol via Mitochondrial Dysfunction Are Strongly Enhanced by the Mitochondria-Targeting Carrier Berberine.
Shi X, Zhang T, Lou H, Song H, Li C, Fan P
Journal of medicinal chemistry 2020 Oct 22;63(20):11786-11800
Journal of medicinal chemistry 2020 Oct 22;63(20):11786-11800
Rosmarinic Acid Alleviates Inflammation, Apoptosis, and Oxidative Stress through Regulating miR-155-5p in a Mice Model of Parkinson's Disease.
Lv R, Du L, Zhou F, Yuan X, Liu X, Zhang L
ACS chemical neuroscience 2020 Oct 21;11(20):3259-3266
ACS chemical neuroscience 2020 Oct 21;11(20):3259-3266
miR-497 regulates fatty acid synthesis via LATS2 in bovine mammary epithelial cells.
Chen Z, Chu S, Liang Y, Xu T, Sun Y, Li M, Zhang H, Wang X, Mao Y, Loor JJ, Wu Y, Yang Z
Food & function 2020 Oct 21;11(10):8625-8636
Food & function 2020 Oct 21;11(10):8625-8636
Amorphous silica nanoparticles accelerated atherosclerotic lesion progression in ApoE(-/-) mice through endoplasmic reticulum stress-mediated CD36 up-regulation in macrophage.
Ma R, Qi Y, Zhao X, Li X, Sun X, Niu P, Li Y, Guo C, Chen R, Sun Z
Particle and fibre toxicology 2020 Oct 2;17(1):50
Particle and fibre toxicology 2020 Oct 2;17(1):50
Sodium butyrate promotes milk fat synthesis in bovine mammary epithelial cells via GPR41 and its downstream signalling pathways.
Cheng J, Zhang Y, Ge Y, Li W, Cao Y, Qu Y, Liu S, Guo Y, Fu S, Liu J
Life sciences 2020 Oct 15;259:118375
Life sciences 2020 Oct 15;259:118375
Designing an eEF2K-Targeting PROTAC small molecule that induces apoptosis in MDA-MB-231 cells.
Liu Y, Zhen Y, Wang G, Yang G, Fu L, Liu B, Ouyang L
European journal of medicinal chemistry 2020 Oct 15;204:112505
European journal of medicinal chemistry 2020 Oct 15;204:112505
Sestrin2 promotes angiogenesis to alleviate brain injury by activating Nrf2 through regulating the interaction between p62 and Keap1 following photothrombotic stroke in rats.
Li Y, Wu J, Yu S, Zhu J, Zhou Y, Wang P, Li L, Zhao Y
Brain research 2020 Oct 15;1745:146948
Brain research 2020 Oct 15;1745:146948
Upregulation of Glutaredoxin 2 alleviates oxygen-glucose deprivation/reoxygenation-induced apoptosis and ROS production in neurons by enhancing Nrf2 signaling via modulation of GSK-3β.
Wen J, Li X, Zheng S, Xiao Y
Brain research 2020 Oct 15;1745:146946
Brain research 2020 Oct 15;1745:146946
A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters.
Wang Y, Zhu Y, Niu J, Deng Q, Guo S, Jiang H, Peng Z, Xue Y, Peng H, Xuan L, Pan G
Toxicology and applied pharmacology 2020 Oct 1;404:115169
Toxicology and applied pharmacology 2020 Oct 1;404:115169
Polydatin executes anticancer effects against glioblastoma multiforme by inhibiting the EGFR-AKT/ERK1/2/STAT3-SOX2/Snail signaling pathway.
Chen Y, Niu J, Li L, Li Z, Jiang J, Zhu M, Dong T, Zhang J, Shi C, Xu P, Lu Y, Jiang Y, Liu P, Chen W
Life sciences 2020 Oct 1;258:118158
Life sciences 2020 Oct 1;258:118158
Notch1 contributes to TNF-α-induced proliferation and migration of airway smooth muscle cells through regulation of the Hes1/PTEN axis.
Li X, Zou F, Lu Y, Fan X, Wu Y, Feng X, Sun X, Liu Y
International immunopharmacology 2020 Nov;88:106911
International immunopharmacology 2020 Nov;88:106911
Knockdown of fatty acid binding protein 4 exacerbates Bacillus Calmette-Guerin infection-induced RAW264.7 cell apoptosis via the endoplasmic reticulum stress pathway.
Yu J, Ma C, Xu Y, Han L, Wu X, Wang Y, Deng G
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2020 Nov;85:104552
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2020 Nov;85:104552
Enhanced therapeutic efficacy of a novel colon-specific nanosystem loading emodin on DSS-induced experimental colitis.
Wang D, Sun M, Zhang Y, Chen Z, Zang S, Li G, Li G, Clark AR, Huang J, Si L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Nov;78:153293
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Nov;78:153293
CaMKII as a key regulator of contrast-induced nephropathy through mPTP opening in HK-2 cells.
Hu C, Zhou G, Liu K, Yin W, Zhou L, Wang J, Chen L, Zuo S, Xie Y, Zuo X
Cellular signalling 2020 Nov;75:109734
Cellular signalling 2020 Nov;75:109734
Histone demethylase Jmjd3 modulates osteoblast apoptosis induced by tumor necrosis factor-alpha through directly targeting RASSF5.
Sun HY, Yang D, Mi J, Yu YQ, Qiu LH
Connective tissue research 2020 Nov;61(6):517-525
Connective tissue research 2020 Nov;61(6):517-525
RNA binding motif protein 10 suppresses lung cancer progression by controlling alternative splicing of eukaryotic translation initiation factor 4H.
Zhang S, Bao Y, Shen X, Pan Y, Sun Y, Xiao M, Chen K, Wei H, Zuo J, Saffen D, Zong WX, Sun Y, Wang Z, Wang Y
EBioMedicine 2020 Nov;61:103067
EBioMedicine 2020 Nov;61:103067
Spatiotemporal heterogeneity of PPARγ expression in porcine uteroplacenta for regulating of placental angiogenesis through VEGF-mediated signalling.
Zhang J, Xue L, Nie A, Yang Q, Peng X, Chen Z, Yang L, Xie Y, Yuan A, Xu J
Reproduction in domestic animals = Zuchthygiene 2020 Nov;55(11):1479-1489
Reproduction in domestic animals = Zuchthygiene 2020 Nov;55(11):1479-1489
Identification of octopus peptide and its promotion of β-casein synthesis in a mouse mammary epithelial cell line.
Cai B, Wan P, Chen H, Chen X, Sun H, Pan J
Journal of food biochemistry 2020 Nov;44(11):e13467
Journal of food biochemistry 2020 Nov;44(11):e13467
Low-intensity pulsed ultrasound protects subchondral bone in rabbit temporomandibular joint osteoarthritis by suppressing TGF-β1/Smad3 pathway.
Yi X, Wu L, Liu J, Qin YX, Li B, Zhou Q
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2020 Nov;38(11):2505-2512
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2020 Nov;38(11):2505-2512
Involvement of NMDAR/PSD-95/nNOS-NO-cGMP pathway in embryonic exposure to BPA induced learning and memory dysfunction of rats.
Yu H, Ma L, Liu D, Wang Y, Pei X, Duan Z, Ma M, Zhang Y
Environmental pollution (Barking, Essex : 1987) 2020 Nov;266(Pt 1):115055
Environmental pollution (Barking, Essex : 1987) 2020 Nov;266(Pt 1):115055
Long noncoding RNA LINC00346 promotes glioma cell migration, invasion and proliferation by up-regulating ROCK1.
Chen X, Li D, Chen L, Hao B, Gao Y, Li L, Zhou C, He X, Cao Y
Journal of cellular and molecular medicine 2020 Nov;24(22):13010-13019
Journal of cellular and molecular medicine 2020 Nov;24(22):13010-13019
MicroRNA-127-5p impairs function of granulosa cells via HMGB2 gene in premature ovarian insufficiency.
Zhang X, Dang Y, Liu R, Zhao S, Ma J, Qin Y
Journal of cellular physiology 2020 Nov;235(11):8826-8838
Journal of cellular physiology 2020 Nov;235(11):8826-8838
Oxidative stress is important in the pathogenesis of stress-related mucosal disease.
Wang X, Zhao Q, Shi H, Qi F, Shi N, Bai D, Li X, Yuan H, Zuo X
Experimental and therapeutic medicine 2020 Nov;20(5):83
Experimental and therapeutic medicine 2020 Nov;20(5):83
Brilliant blue G attenuates neuro-inflammation via regulating MAPKs and NF-κB signaling pathways in lipopolysaccharide-induced BV2 microglia cells.
Wang W, Huang F, Jiang W, Wang W, Xiang J
Experimental and therapeutic medicine 2020 Nov;20(5):116
Experimental and therapeutic medicine 2020 Nov;20(5):116
Methylprednisolone potentiates tetrandrine pharmacodynamics against human T lymphoblastoid leukemia MOLT-4 cells via regulation of NF-κB activation and cell cycle transition.
Xu W, Chen S, Wang X, Wu H, Yamada H, Hirano T
Steroids 2020 Nov;163:108714
Steroids 2020 Nov;163:108714
Activation of angiotensin II type-2 receptor protects against cigarette smoke-induced COPD.
Mei D, Tan WSD, Liao W, Heng CKM, Wong WSF
Pharmacological research 2020 Nov;161:105223
Pharmacological research 2020 Nov;161:105223
Up-regulation of astrocyte excitatory amino acid transporter 2 alleviates central sensitization in a rat model of chronic migraine.
Zhou X, Liang J, Wang J, Fei Z, Qin G, Zhang D, Zhou J, Chen L
Journal of neurochemistry 2020 Nov;155(4):370-389
Journal of neurochemistry 2020 Nov;155(4):370-389
TRIM25 upregulation by Mycobacterium tuberculosis infection promotes intracellular survival of M.tb in RAW264.7 cells.
Liu H, Zhu T, Li Q, Xiong X, Wang J, Zhu X, Zhou X, Zhang L, Zhu Y, Peng Y, Chen Y, Hu C, Chen H, Guo A
Microbial pathogenesis 2020 Nov;148:104456
Microbial pathogenesis 2020 Nov;148:104456
Indirubin alleviates bleomycin-induced pulmonary fibrosis in mice by suppressing fibroblast to myofibroblast differentiation.
Wang Q, Yu J, Hu Y, Chen X, Zhang L, Pan T, Miao K, Mou Y, Xu Y, Xiong W, Wang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110715
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110715
Nucleoredoxin interaction with flightless-I/actin complex is differentially altered in alcoholic liver disease.
Alarcón-Sánchez BR, Guerrero-Escalera D, Rosas-Madrigal S, Ivette Aparicio-Bautista D, Reyes-Gordillo K, Lakshman MR, Ortiz-Fernández A, Quezada H, Medina-Contreras Ó, Villa-Treviño S, Isael Pérez-Carreón J, Arellanes-Robledo J
Basic & clinical pharmacology & toxicology 2020 Nov;127(5):389-404
Basic & clinical pharmacology & toxicology 2020 Nov;127(5):389-404
Mycoplasma bovis-generated reactive oxygen species and induced apoptosis in bovine mammary epithelial cell cultures.
Liu Y, Zhou M, Xu S, Khan MA, Shi Y, Qu W, Gao J, Liu G, Kastelic JP, Han B
Journal of dairy science 2020 Nov;103(11):10429-10445
Journal of dairy science 2020 Nov;103(11):10429-10445
Sox13 promotes hepatocellular carcinoma metastasis by transcriptionally activating Twist1.
Feng M, Fang F, Fang T, Jiao H, You S, Wang X, Zhao W
Laboratory investigation; a journal of technical methods and pathology 2020 Nov;100(11):1400-1410
Laboratory investigation; a journal of technical methods and pathology 2020 Nov;100(11):1400-1410
TMEM176A acts as a tumor suppressor gene in pancreatic cancer by inhibiting ERK signaling.
Guo Y, Cao F, Hu S, Liu S, Sun H, Li A, Li F
Discovery medicine 2020 Nov-Dec;30(161):145-153
Discovery medicine 2020 Nov-Dec;30(161):145-153
Deficiency of microglial Hv1 channel is associated with activation of autophagic pathway and ROS production in LPC-induced demyelination mouse model.
Chen M, Yang LL, Hu ZW, Qin C, Zhou LQ, Duan YL, Bosco DB, Wu LJ, Zhan KB, Xu SB, Tian DS
Journal of neuroinflammation 2020 Nov 6;17(1):333
Journal of neuroinflammation 2020 Nov 6;17(1):333
Effects of Osthole on Progesterone Secretion in Chicken Preovulatory Follicles Granulosa Cells.
Sun N, Zhang Y, Hou Y, Yi Y, Guo J, Zheng X, Sun P, Sun Y, Khan A, Li H
Animals : an open access journal from MDPI 2020 Nov 4;10(11)
Animals : an open access journal from MDPI 2020 Nov 4;10(11)
Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation.
Quan L, Ohgaki R, Hara S, Okuda S, Wei L, Okanishi H, Nagamori S, Endou H, Kanai Y
Journal of experimental & clinical cancer research : CR 2020 Nov 30;39(1):266
Journal of experimental & clinical cancer research : CR 2020 Nov 30;39(1):266
Anthocyanins decrease the internalization of TiO(2) nanoparticles into 3D Caco-2 spheroids.
Wang J, Zhang J, Li S, Huang C, Xie Y, Cao Y
Food chemistry 2020 Nov 30;331:127360
Food chemistry 2020 Nov 30;331:127360
Hypoxia induces sorafenib resistance mediated by autophagy via activating FOXO3a in hepatocellular carcinoma.
Liang C, Dong Z, Cai X, Shen J, Xu Y, Zhang M, Li H, Yu W, Chen W
Cell death & disease 2020 Nov 29;11(11):1017
Cell death & disease 2020 Nov 29;11(11):1017
Effective RNA Knockdown Using CRISPR-Cas13a and Molecular Targeting of the EML4-ALK Transcript in H3122 Lung Cancer Cells.
Saifullah, Sakari M, Suzuki T, Yano S, Tsukahara T
International journal of molecular sciences 2020 Nov 24;21(23)
International journal of molecular sciences 2020 Nov 24;21(23)
MiR-103a-3p promotes tumour glycolysis in colorectal cancer via hippo/YAP1/HIF1A axis.
Sun Z, Zhang Q, Yuan W, Li X, Chen C, Guo Y, Shao B, Dang Q, Zhou Q, Wang Q, Wang G, Liu J, Kan Q
Journal of experimental & clinical cancer research : CR 2020 Nov 20;39(1):250
Journal of experimental & clinical cancer research : CR 2020 Nov 20;39(1):250
Velvet antler polypeptide prevents the disruption of hepatic tight junctions via inhibiting oxidative stress in cholestatic mice and liver cell lines.
Li L, Yang F, Jia R, Yan P, Ma L
Food & function 2020 Nov 18;11(11):9752-9763
Food & function 2020 Nov 18;11(11):9752-9763
Identification of Milk Fat Metabolism-Related Pathways of the Bovine Mammary Gland during Mid and Late Lactation and Functional Verification of the ACSL4 Gene.
Fan Y, Han Z, Lu X, Zhang H, Arbab AAI, Loor JJ, Yang Y, Yang Z
Genes 2020 Nov 16;11(11)
Genes 2020 Nov 16;11(11)
Eurocristatine, a plant alkaloid from Eurotium cristatum, alleviates insulin resistance in db/db diabetic mice via activation of PI3K/AKT signaling pathway.
Zhang H, Hui J, Yang J, Deng J, Fan D
European journal of pharmacology 2020 Nov 15;887:173557
European journal of pharmacology 2020 Nov 15;887:173557
Baicalein ameliorates ionizing radiation-induced injuries by rebalancing gut microbiota and inhibiting apoptosis.
Wang M, Dong Y, Wu J, Li H, Zhang Y, Fan S, Li D
Life sciences 2020 Nov 15;261:118463
Life sciences 2020 Nov 15;261:118463
A novel polysaccharide from Acorus tatarinowii protects against LPS-induced neuroinflammation and neurotoxicity by inhibiting TLR4-mediated MyD88/NF-κB and PI3K/Akt signaling pathways.
Zhong J, Qiu X, Yu Q, Chen H, Yan C
International journal of biological macromolecules 2020 Nov 15;163:464-475
International journal of biological macromolecules 2020 Nov 15;163:464-475
Binding properties of marine bromophenols with human protein tyrosine phosphatase 1B: Molecular docking, surface plasmon resonance and cellular insulin resistance study.
Luo J, Zhang R, Wang X, Hou Z, Guo S, Jiang B
International journal of biological macromolecules 2020 Nov 15;163:200-208
International journal of biological macromolecules 2020 Nov 15;163:200-208
Targeting HMGB3/hTERT axis for radioresistance in cervical cancer.
Li Z, Zhang Y, Sui S, Hua Y, Zhao A, Tian X, Wang R, Guo W, Yu W, Zou K, Deng W, He L, Zou L
Journal of experimental & clinical cancer research : CR 2020 Nov 13;39(1):243
Journal of experimental & clinical cancer research : CR 2020 Nov 13;39(1):243
Synergism of TNF-α and IFN-γ triggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes.
Karki R, Sharma BR, Tuladhar S, Williams EP, Zalduondo L, Samir P, Zheng M, Sundaram B, Banoth B, Malireddi RKS, Schreiner P, Neale G, Vogel P, Webby R, Jonsson CB, Kanneganti TD
bioRxiv : the preprint server for biology 2020 Nov 13;
bioRxiv : the preprint server for biology 2020 Nov 13;
Duck enteritis virus pUL47, as a late structural protein localized in the nucleus, mainly depends on residues 40 to 50 and 768 to 777 and inhibits IFN-β signalling by interacting with STAT1.
He T, Wang M, Cheng A, Yang Q, Jia R, Wu Y, Huang J, Chen S, Zhao XX, Liu M, Zhu D, Zhang S, Ou X, Mao S, Gao Q, Sun D, Wen X, Tian B, Liu Y, Yu Y, Zhang L, Pan L, Chen X
Veterinary research 2020 Nov 11;51(1):135
Veterinary research 2020 Nov 11;51(1):135
Immunoproteasome is up-regulated in rotenone-induced Parkinson's disease rat model.
Sun C, Jia G, Wang X, Wang Y, Liu Y
Neuroscience letters 2020 Nov 1;738:135360
Neuroscience letters 2020 Nov 1;738:135360
Berberine inhibits proliferation and induces G0/G1 phase arrest in colorectal cancer cells by downregulating IGF2BP3.
Zhang Y, Liu X, Yu M, Xu M, Xiao Y, Ma W, Huang L, Li X, Ye X
Life sciences 2020 Nov 1;260:118413
Life sciences 2020 Nov 1;260:118413
iTRAQ-based quantitative proteomic analysis of the therapeutic effects of 2% hydrogen gas inhalation on brain injury in septic mice.
Xie K, Lian N, Kan Y, Yang M, Pan J, Yu Y, Yu Y
Brain research 2020 Nov 1;1746:147003
Brain research 2020 Nov 1;1746:147003
Combination of N, N'-dicyclohexyl-N-arachidonic acylurea and tacrolimus prolongs cardiac allograft survival in mice.
An K, Qin Q, Yu S, Xue M, Wang Z, Lin Q, Ma Y, Yan G, Mo S, Chen Y, Zhang L, Zhong J, Qi Z, Xia J
Immunology and cell biology 2020 May;98(5):382-396
Immunology and cell biology 2020 May;98(5):382-396
Long non-coding RNA OIP5-AS1 promotes pancreatic cancer cell growth through sponging miR-342-3p via AKT/ERK signaling pathway.
Meng X, Ma J, Wang B, Wu X, Liu Z
Journal of physiology and biochemistry 2020 May;76(2):301-315
Journal of physiology and biochemistry 2020 May;76(2):301-315
Role of fucosyltransferase IV in the migration and invasion of human melanoma cells.
Shan X, Dong W, Zhang L, Cai X, Zhao Y, Chen Q, Yan Q, Liu J
IUBMB life 2020 May;72(5):942-956
IUBMB life 2020 May;72(5):942-956
OGDHL silencing promotes hepatocellular carcinoma by reprogramming glutamine metabolism.
Dai W, Xu L, Yu X, Zhang G, Guo H, Liu H, Song G, Weng S, Dong L, Zhu J, Liu T, Guo C, Shen X
Journal of hepatology 2020 May;72(5):909-923
Journal of hepatology 2020 May;72(5):909-923
miR-142-5P regulates triglyceride by targeting CTNNB1 in goat mammary epithelial cells.
Sui M, Wang Z, Xi D, Wang H
Reproduction in domestic animals = Zuchthygiene 2020 May;55(5):613-623
Reproduction in domestic animals = Zuchthygiene 2020 May;55(5):613-623
Transcriptome sequencing analysis of mono‑ADP‑ribosylation in colorectal cancer cells.
Zhang NN, Lin T, Xiao M, Li QS, Li X, Yang L, Wang CL, Wang YL
Oncology reports 2020 May;43(5):1413-1428
Oncology reports 2020 May;43(5):1413-1428
Annexin-1 Mimetic Peptide Ac2-26 Suppresses Inflammatory Mediators in LPS-Induced Astrocytes and Ameliorates Pain Hypersensitivity in a Rat Model of Inflammatory Pain.
Luo Z, Wang H, Fang S, Li L, Li X, Shi J, Zhu M, Tan Z, Lu Z
Cellular and molecular neurobiology 2020 May;40(4):569-585
Cellular and molecular neurobiology 2020 May;40(4):569-585
Mitochondrial dysfunction is involved in aristolochic acid I-induced apoptosis in renal proximal tubular epithelial cells.
Liu X, Wu J, Wang J, Feng X, Wu H, Huang R, Fan J, Yu X, Yang X
Human & experimental toxicology 2020 May;39(5):673-682
Human & experimental toxicology 2020 May;39(5):673-682
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
Wang Y, Chen J, Li S, Zhang X, Guo Z, Hu J, Shao X, Song N, Zhao Y, Li H, Yang G, Xu C, Wei C
Redox biology 2020 May;32:101514
Redox biology 2020 May;32:101514
Programmable prodrug micelle with size-shrinkage and charge-reversal for chemotherapy-improved IDO immunotherapy.
Dai L, Li X, Yao M, Niu P, Yuan X, Li K, Chen M, Fu Z, Duan X, Liu H, Cai K, Yang H
Biomaterials 2020 May;241:119901
Biomaterials 2020 May;241:119901
Lin28a protects against diabetic cardiomyopathy through Mst1 inhibition.
You P, Cheng Z, He X, Deng J, Diao J, Chen H, Cheng G
Journal of cellular physiology 2020 May;235(5):4455-4465
Journal of cellular physiology 2020 May;235(5):4455-4465
PM2.5 in poultry houses synergizes with Pseudomonas aeruginosa to aggravate lung inflammation in mice through the NF-κB pathway.
Li M, Wei X, Li Y, Feng T, Jiang L, Zhu H, Yu X, Tang J, Chen G, Zhang J, Zhang X
Journal of veterinary science 2020 May;21(3):e46
Journal of veterinary science 2020 May;21(3):e46
Shear stress stimulates integrin β1 trafficking and increases directional migration of cancer cells via promoting deacetylation of microtubules.
Tang K, Li S, Li P, Xia Q, Yang R, Li T, Li L, Jiang Y, Qin X, Yang H, Wu C, You F, Tan Y, Liu Y
Biochimica et biophysica acta. Molecular cell research 2020 May;1867(5):118676
Biochimica et biophysica acta. Molecular cell research 2020 May;1867(5):118676
TOPORS, a tumor suppressor protein, contributes to the maintenance of higher-order chromatin architecture.
Ji L, Huo X, Zhang Y, Yan Z, Wang Q, Wen B
Biochimica et biophysica acta. Gene regulatory mechanisms 2020 May;1863(5):194518
Biochimica et biophysica acta. Gene regulatory mechanisms 2020 May;1863(5):194518
Protective effect of cilastatin against diclofenac-induced nephrotoxicity through interaction with diclofenac acyl glucuronide via organic anion transporters.
Huo X, Meng Q, Wang C, Wu J, Wang C, Zhu Y, Ma X, Sun H, Liu K
British journal of pharmacology 2020 May;177(9):1933-1948
British journal of pharmacology 2020 May;177(9):1933-1948
Palmatine induces G2/M phase arrest and mitochondrial-associated pathway apoptosis in colon cancer cells by targeting AURKA.
Liu X, Zhang Y, Wu S, Xu M, Shen Y, Yu M, Fan J, Wei S, Xu C, Huang L, Zhao H, Li X, Ye X
Biochemical pharmacology 2020 May;175:113933
Biochemical pharmacology 2020 May;175:113933
Protective effect of ginsenoside Rg5 against kidney injury via inhibition of NLRP3 inflammasome activation and the MAPK signaling pathway in high-fat diet/streptozotocin-induced diabetic mice.
Zhu Y, Zhu C, Yang H, Deng J, Fan D
Pharmacological research 2020 May;155:104746
Pharmacological research 2020 May;155:104746
Elevated SRC3 expression predicts pemetrexed resistance in lung adenocarcinoma.
Chen Y, Sun Y, Zhao W, Ma Y, Yan Z, Nie X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109958
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109958
LncRNA MFI2-AS1 promotes HCC progression and metastasis by acting as a competing endogenous RNA of miR-134 to upregulate FOXM1 expression.
Wei Y, Wang Z, Zong Y, Deng D, Chen P, Lu J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109890
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109890
Protein kinase CK2 participates in estrogen-mediated endothelial progenitor cell homing to endometriotic lesions through stromal cells in a stromal cell-derived factor-1- CXCR4-dependent manner.
Zhao R, Feng D, Zhuang G, Liu Y, Chi S, Zhang J, Zhou X, Zhang W, Wang H
Fertility and sterility 2020 May;113(5):1067-1079.e5
Fertility and sterility 2020 May;113(5):1067-1079.e5
BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma.
Yu YP, Cai LC, Wang XY, Cheng SY, Zhang DM, Jian WG, Wang TD, Yang JK, Yang KB, Zhang C
Cancer science 2020 May;111(5):1555-1566
Cancer science 2020 May;111(5):1555-1566
Suppression of experimental atrial fibrillation in a canine model of rapid atrial pacing by the phosphodiesterase 3 inhibitor cilostazol.
Zhao Z, Li R, Wang X, Li J, Xu X, Liu T, Liu E, Li G
Journal of electrocardiology 2020 May-Jun;60:151-158
Journal of electrocardiology 2020 May-Jun;60:151-158
Mitochondria-related miR-574 reduces sperm ATP by targeting ND5 in aging males.
Ma J, Chen Q, Wang S, Ma R, Jing J, Yang Y, Feng Y, Zou Z, Zhang Y, Ge X, Xue T, Liang K, Cao S, Wang D, Chen L, Yao B
Aging 2020 May 7;12(9):8321-8338
Aging 2020 May 7;12(9):8321-8338
Rare Neurologic Disease-Associated Mutations of AIMP1 are Related with Inhibitory Neuronal Differentiation Which is Reversed by Ibuprofen.
Takeuchi Y, Tanaka M, Okura N, Fukui Y, Noguchi K, Hayashi Y, Torii T, Ooizumi H, Ohbuchi K, Mizoguchi K, Miyamoto Y, Yamauchi J
Medicines (Basel, Switzerland) 2020 May 6;7(5)
Medicines (Basel, Switzerland) 2020 May 6;7(5)
Artesunate attenuates 2, 4-dinitrochlorobenzene-induced atopic dermatitis by down-regulating Th17 cell responses in BALB/c mice.
Bai XY, Liu P, Chai YW, Wang Y, Ren SH, Li YY, Zhou H
European journal of pharmacology 2020 May 5;874:173020
European journal of pharmacology 2020 May 5;874:173020
Effect of miR-195-5p on cardiomyocyte apoptosis in rats with heart failure by regulating TGF-β1/Smad3 signaling pathway.
Xie C, Qi H, Huan L, Yang Y
Bioscience reports 2020 May 29;40(5)
Bioscience reports 2020 May 29;40(5)
TET2-mediated Cdkn2A DNA hydroxymethylation in midbrain dopaminergic neuron injury of Parkinson's disease.
Wu TT, Liu T, Li X, Chen YJ, Chen TJ, Zhu XY, Chen JL, Li Q, Liu Y, Feng Y, Wu YC
Human molecular genetics 2020 May 28;29(8):1239-1252
Human molecular genetics 2020 May 28;29(8):1239-1252
The Lumiptosome, an engineered luminescent form of the apoptosome can report cell death by using the same Apaf-1 dependent pathway.
Hosseini ES, Nikkhah M, Hamidieh AA, Fearnhead HO, Concordet JP, Hosseinkhani S
Journal of cell science 2020 May 27;133(10)
Journal of cell science 2020 May 27;133(10)
P-21-activated kinase 1 contributes to tumor angiogenesis upon photodynamic therapy via the HIF-1α/VEGF pathway.
Jiang S, Gao Y, Yu QH, Li M, Cheng X, Hu SB, Song ZF, Zheng QC
Biochemical and biophysical research communications 2020 May 21;526(1):98-104
Biochemical and biophysical research communications 2020 May 21;526(1):98-104
Neddylation-mediated Nedd4-2 activation regulates ubiquitination modification of renal NBCe1.
Tu J, Zhang B, Fang G, Chang W, Zhao Y
Experimental cell research 2020 May 15;390(2):111958
Experimental cell research 2020 May 15;390(2):111958
Concentration and Duration of Indoxyl Sulfate Exposure Affects Osteoclastogenesis by Regulating NFATc1 via Aryl Hydrocarbon Receptor.
Liu WC, Shyu JF, Lim PS, Fang TC, Lu CL, Zheng CM, Hou YC, Wu CC, Lin YF, Lu KC
International journal of molecular sciences 2020 May 15;21(10)
International journal of molecular sciences 2020 May 15;21(10)
Androgen aggravates liver fibrosis by activation of NLRP3 inflammasome in CCl(4)-induced liver injury mouse model.
Ma X, Zhou Y, Qiao B, Jiang S, Shen Q, Han Y, Liu A, Chen X, Wei L, Zhou L, Zhao J
American journal of physiology. Endocrinology and metabolism 2020 May 1;318(5):E817-E829
American journal of physiology. Endocrinology and metabolism 2020 May 1;318(5):E817-E829
In vitro and in vivo anti-Listeria effect of Succinoglycan Riclin through regulating MAPK/IL-6 axis and metabolic profiling.
Wu Z, Cheng Y, Yang Y, Gao Y, Sun X, Wang L, Sun Q, Zhang J, Xu X
International journal of biological macromolecules 2020 May 1;150:802-813
International journal of biological macromolecules 2020 May 1;150:802-813
Blueberry Prevents the Bladder Dysfunction in Bladder Outlet Obstruction Rats by Attenuating Oxidative Stress and Suppressing Bladder Remodeling.
Miyazaki N, Katsura R, Hamada K, Suzutani T
Nutrients 2020 May 1;12(5)
Nutrients 2020 May 1;12(5)
Ketamine attenuates high-glucose-mediated endothelial inflammation in human umbilical vein endothelial cells.
Wang T, Zhu H, Hou Y, Duan W, Meng F, Liu Y
Canadian journal of physiology and pharmacology 2020 Mar;98(3):156-161
Canadian journal of physiology and pharmacology 2020 Mar;98(3):156-161
Interleukin-4 Restores Insulin Sensitivity in Insulin-Resistant Osteoblasts by Increasing the Expression of Insulin Receptor Substrate 1.
Chao R, Li D, Yue Z, Huang C, Kou Y, Zhou Q, Gao Y, Hasegawa T, Guo J, Li M
Biochemistry. Biokhimiia 2020 Mar;85(3):334-343
Biochemistry. Biokhimiia 2020 Mar;85(3):334-343
NLRP6 expressed in astrocytes aggravates neurons injury after OGD/R through activating the inflammasome and inducing pyroptosis.
Zhang J, Jiang N, Zhang L, Meng C, Zhao J, Wu J
International immunopharmacology 2020 Mar;80:106183
International immunopharmacology 2020 Mar;80:106183
Dihydroartemisinin inhibits the proliferation of IgAN mesangial cells through the mTOR signaling pathway.
Xia M, Liu D, Tang X, Liu Y, Liu H, Liu Y, Chen G, Liu H
International immunopharmacology 2020 Mar;80:106125
International immunopharmacology 2020 Mar;80:106125
JTE-013 supplementation improves erectile dysfunction in rats with streptozotocin-induced type Ⅰ diabetes through the inhibition of the rho-kinase pathway, fibrosis, and apoptosis.
Liu K, Cui K, Feng H, Li R, Lin H, Chen Y, Zhang Y, Chen Z, Yuan H, Li M, Wang T, Lan R, Liu J, Rao K, Wen B
Andrology 2020 Mar;8(2):497-508
Andrology 2020 Mar;8(2):497-508
Danshen formula granule and salvianic acid A alleviate ethanol-induced neurotoxicity.
Li Y, Chen H, Yang Y, Niu M, Wang J, Wu Y, Niu L, Liu H, Bao D
Journal of natural medicines 2020 Mar;74(2):399-408
Journal of natural medicines 2020 Mar;74(2):399-408
Resveratrol protects the integrity of alveolar epithelial barrier via SIRT1/PTEN/p-Akt pathway in methamphetamine-induced chronic lung injury.
Wang X, Liu M, Zhu MJ, Shi L, Liu L, Zhao YL, Cheng L, Gu YJ, Zhou MY, Chen L, Kumar A, Wang Y
Cell proliferation 2020 Mar;53(3):e12773
Cell proliferation 2020 Mar;53(3):e12773
Integrin β3 Modulates TLR4-Mediated Inflammation by Regulation of CD14 Expression in Macrophages in Septic Condition.
Chen Z, Wang S, Chen Y, Shao Z, Yu Z, Mei S, Li Q
Shock (Augusta, Ga.) 2020 Mar;53(3):335-343
Shock (Augusta, Ga.) 2020 Mar;53(3):335-343
Inhibitory mechanism of muscone in liver cancer involves the induction of apoptosis and autophagy.
Qi W, Li Z, Yang C, Jiangshan Dai J, Zhang Q, Wang D, Wu C, Xia L, Xu S
Oncology reports 2020 Mar;43(3):839-850
Oncology reports 2020 Mar;43(3):839-850
Samarium enriches antitumor activity of ZnO nanoparticles via downregulation of CXCR4 receptor and cytochrome P450.
Nabeel AI
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2020 Mar;42(3):1010428320909999
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2020 Mar;42(3):1010428320909999
Cyclovirobuxine D Exerts Anticancer Effects by Suppressing the EGFR-FAK-AKT/ERK1/2-Slug Signaling Pathway in Human Hepatocellular Carcinoma.
Zhang J, Chen Y, Lin J, Jia R, An T, Dong T, Zhang Y, Yang X
DNA and cell biology 2020 Mar;39(3):355-367
DNA and cell biology 2020 Mar;39(3):355-367
Lysophosphatidic acid receptor 4 regulates osteogenic and adipogenic differentiation of progenitor cells via inactivation of RhoA/ROCK1/β-catenin signaling.
Xie Y, Wang X, Wu X, Tian L, Zhou J, Li X, Wang B
Stem cells (Dayton, Ohio) 2020 Mar;38(3):451-463
Stem cells (Dayton, Ohio) 2020 Mar;38(3):451-463
HUWE1 promotes EGFR ubiquitination and degradation to protect against renal tubulointerstitial fibrosis.
Zhu Q, Dong H, Bukhari AA, Zhao A, Li M, Sun Y, Zhang X, Cao C, Su D, Liang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4591-4601
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4591-4601
Molecular hydrogen regulates PTEN-AKT-mTOR signaling via ROS to alleviate peritoneal dialysis-related peritoneal fibrosis.
Lu H, Chen W, Liu W, Si Y, Zhao T, Lai X, Kang Z, Sun X, Guo Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4134-4146
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4134-4146
Recombinant Human Milk Fat Globule-Epidermal Growth Factor 8 Attenuates Microthrombosis after Subarachnoid Hemorrhage in Rats.
Wang J, Zuo Y, Zhuang K, Luo K, Yan X, Li J, Zhang JH, Liu F
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2020 Mar;29(3):104536
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2020 Mar;29(3):104536
Blockade of HSP70 by VER-155008 synergistically enhances bortezomib-induced cytotoxicity in multiple myeloma.
Huang L, Wang Y, Bai J, Yang Y, Wang F, Feng Y, Zhang R, Li F, Zhang P, Lv N, Lei L, Hu J, He A
Cell stress & chaperones 2020 Mar;25(2):357-367
Cell stress & chaperones 2020 Mar;25(2):357-367
The marine-derived furanone reduces intracellular lipid accumulation in vitro by targeting LXRα and PPARα.
Li T, Hu SM, Pang XY, Wang JF, Yin JY, Li FH, Wang J, Yang XQ, Xia B, Liu YH, Song WG, Guo SD
Journal of cellular and molecular medicine 2020 Mar;24(6):3384-3398
Journal of cellular and molecular medicine 2020 Mar;24(6):3384-3398
Mechanism of the hypoxia inducible factor 1/hypoxic response element pathway in rat myocardial ischemia/diazoxide post‑conditioning.
Li J, Zhou W, Chen W, Wang H, Zhang Y, Yu T
Molecular medicine reports 2020 Mar;21(3):1527-1536
Molecular medicine reports 2020 Mar;21(3):1527-1536
Ginsenosides reduce body weight and ameliorate hepatic steatosis in high fat diet‑induced obese mice via endoplasmic reticulum stress and p‑STAT3/STAT3 signaling.
Yao Y
Molecular medicine reports 2020 Mar;21(3):1059-1070
Molecular medicine reports 2020 Mar;21(3):1059-1070
Cystatin C promotes cognitive dysfunction in rats with cerebral microbleeds by inhibiting the ERK/synapsin Ia/Ib pathway.
Yu G, Sun X, Li L, Huang L, Liu H, Wang S, Ren Z, Zhang Y
Experimental and therapeutic medicine 2020 Mar;19(3):2282-2290
Experimental and therapeutic medicine 2020 Mar;19(3):2282-2290
WHIMP links the actin nucleation machinery to Src-family kinase signaling during protrusion and motility.
Kabrawala S, Zimmer MD, Campellone KG
PLoS genetics 2020 Mar;16(3):e1008694
PLoS genetics 2020 Mar;16(3):e1008694
LongShengZhi capsule inhibits doxorubicin-induced heart failure by anti-oxidative stress.
Xu S, Wang Y, Yu M, Wang D, Liang Y, Chen Y, Liao C, Xie Z, Zhao B, Han J, Duan Y, Yang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109803
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109803
The mechanism of PDA/PEI/5-Fu coated esophageal stent material on inhibiting cancer associated pathological cells.
Zhang K, Bai Y, Xu R, Li J, Guan F
Journal of biomedical materials research. Part A 2020 Mar;108(3):814-821
Journal of biomedical materials research. Part A 2020 Mar;108(3):814-821
DJ-1 exerts anti-inflammatory effects and regulates NLRX1-TRAF6 via SHP-1 in stroke.
Peng L, Zhou Y, Jiang N, Wang T, Zhu J, Chen Y, Li L, Zhang J, Yu S, Zhao Y
Journal of neuroinflammation 2020 Mar 9;17(1):81
Journal of neuroinflammation 2020 Mar 9;17(1):81
Transcription co-activator P300 activates Elk1-aPKC-ι signaling mediated epithelial-to-mesenchymal transition and malignancy in hepatocellular carcinoma.
Ma C, Huang S, Xu L, Tian L, Yang Y, Wang J
Oncogenesis 2020 Mar 6;9(3):32
Oncogenesis 2020 Mar 6;9(3):32
Quantitative Mitochondrial Proteomics Reveals ANXA7 as a Crucial Factor in Mitophagy.
Meng K, Lu S, Yan X, Sun Y, Gao J, Wang Y, Yin X, Sun Z, He QY
Journal of proteome research 2020 Mar 6;19(3):1275-1284
Journal of proteome research 2020 Mar 6;19(3):1275-1284
miR-17 regulates the proliferation and differentiation of retinal progenitor cells by targeting CHMP1A.
Sun N, Zhang D, Ni N, Tang Z, Gao H, Ju Y, Dai X, Wang J, Gu P, Ji J
Biochemical and biophysical research communications 2020 Mar 5;523(2):493-499
Biochemical and biophysical research communications 2020 Mar 5;523(2):493-499
SIRT3 inhibits cardiac hypertrophy by regulating PARP-1 activity.
Feng X, Wang Y, Chen W, Xu S, Li L, Geng Y, Shen A, Gao H, Zhang L, Liu S
Aging 2020 Mar 4;12(5):4178-4192
Aging 2020 Mar 4;12(5):4178-4192
BCAP31, a cancer/testis antigen-like protein, can act as a probe for non-small-cell lung cancer metastasis.
Wang J, Jiang D, Li Z, Yang S, Zhou J, Zhang G, Zhang Z, Sun Y, Zhang Z, Li X, Tao L, Shi J, Lu Y, Zheng L, Song C, Yang K
Scientific reports 2020 Mar 4;10(1):4025
Scientific reports 2020 Mar 4;10(1):4025
(20S)G-Rh2 Inhibits NF-κB Regulated Epithelial-Mesenchymal Transition by Targeting Annexin A2.
Wang YS, Li H, Li Y, Zhang S, Jin YH
Biomolecules 2020 Mar 31;10(4)
Biomolecules 2020 Mar 31;10(4)
5-HT(1A)R alleviates Aβ-induced cognitive decline and neuroinflammation through crosstalk with NF-κB pathway in mice.
Wang M, Zong HF, Chang KW, Han H, Yasir Rizvi M, Iffat Neha S, Li ZY, Yang WN, Qian YH
International immunopharmacology 2020 Mar 3;82:106354
International immunopharmacology 2020 Mar 3;82:106354
The Agpat4/LPA axis in colorectal cancer cells regulates antitumor responses via p38/p65 signaling in macrophages.
Zhang D, Shi R, Xiang W, Kang X, Tang B, Li C, Gao L, Zhang X, Zhang L, Dai R, Miao H
Signal transduction and targeted therapy 2020 Mar 27;5(1):24
Signal transduction and targeted therapy 2020 Mar 27;5(1):24
LINC00978 promotes hepatocellular carcinoma carcinogenesis partly via activating the MAPK/ERK pathway.
Zhang Q, Cheng S, Cao L, Yang J, Wang Y, Chen Y
Bioscience reports 2020 Mar 27;40(3)
Bioscience reports 2020 Mar 27;40(3)
Posttranslational lysine 2-hydroxyisobutyrylation of human sperm tail proteins affects motility.
Cheng YM, Peng Z, Chen HY, Pan TT, Hu XN, Wang F, Luo T
Human reproduction (Oxford, England) 2020 Mar 27;35(3):494-503
Human reproduction (Oxford, England) 2020 Mar 27;35(3):494-503
Design, Synthesis, and Biological Evaluation of Imidazo[1,2-a]pyridine Derivatives as Novel PI3K/mTOR Dual Inhibitors.
Yu Y, Han Y, Zhang F, Gao Z, Zhu T, Dong S, Ma M
Journal of medicinal chemistry 2020 Mar 26;63(6):3028-3046
Journal of medicinal chemistry 2020 Mar 26;63(6):3028-3046
Dendrobium officinale polysaccharides protected against ethanol-induced acute liver injury in vivo and in vitro via the TLR4/NF-κB signaling pathway.
Yang K, Zhan L, Lu T, Zhou C, Chen X, Dong Y, Lv G, Chen S
Cytokine 2020 Mar 26;130:155058
Cytokine 2020 Mar 26;130:155058
Optimization of Experimental Variables Influencing Apoptosome Biosensor in HEK293T Cells.
Oladzad A, Nikkhah M, Hosseinkhani S
Sensors (Basel, Switzerland) 2020 Mar 23;20(6)
Sensors (Basel, Switzerland) 2020 Mar 23;20(6)
Protective effects of panax notoginseng saponin on dextran sulfate sodium-induced colitis in rats through phosphoinositide-3-kinase protein kinase B signaling pathway inhibition.
Lu QG, Zeng L, Li XH, Liu Y, Du XF, Bai GM, Yan X
World journal of gastroenterology 2020 Mar 21;26(11):1156-1171
World journal of gastroenterology 2020 Mar 21;26(11):1156-1171
Extrahepatic deficiency of transferrin receptor 2 is associated with increased erythropoiesis independent of iron overload.
Wortham AM, Goldman DC, Chen J, Fleming WH, Zhang AS, Enns CA
The Journal of biological chemistry 2020 Mar 20;295(12):3906-3917
The Journal of biological chemistry 2020 Mar 20;295(12):3906-3917
Dual regulation of p53 by the ribosome maturation factor SBDS.
Hao Q, Wang J, Chen Y, Wang S, Cao M, Lu H, Zhou X
Cell death & disease 2020 Mar 20;11(3):197
Cell death & disease 2020 Mar 20;11(3):197
Regulation of the linear ubiquitination of STAT1 controls antiviral interferon signaling.
Zuo Y, Feng Q, Jin L, Huang F, Miao Y, Liu J, Xu Y, Chen X, Zhang H, Guo T, Yuan Y, Zhang L, Wang J, Zheng H
Nature communications 2020 Mar 2;11(1):1146
Nature communications 2020 Mar 2;11(1):1146
HNF-1a promotes pancreatic cancer growth and apoptosis resistance via its target gene PKLR.
Fan Z, Fan K, Deng S, Gong Y, Qian Y, Huang Q, Yang C, Cheng H, Jin K, Luo G, Liu C, Yu X
Acta biochimica et biophysica Sinica 2020 Mar 18;52(3):241-250
Acta biochimica et biophysica Sinica 2020 Mar 18;52(3):241-250
Alarmin HMGB1 Plays a Detrimental Role in Hippocampal Dysfunction Caused by Hypoxia-Ischemia Insult in Neonatal Mice: Evidence from the Application of the HMGB1 Inhibitor Glycyrrhizin.
Le K, Wu S, Chibaatar E, Ali AI, Guo Y
ACS chemical neuroscience 2020 Mar 18;11(6):979-993
ACS chemical neuroscience 2020 Mar 18;11(6):979-993
Identification of ALPPL2 as a Naive Pluripotent State-Specific Surface Protein Essential for Human Naive Pluripotency Regulation.
Bi Y, Tu Z, Zhang Y, Yang P, Guo M, Zhu X, Zhao C, Zhou J, Wang H, Wang Y, Gao S
Cell reports 2020 Mar 17;30(11):3917-3931.e5
Cell reports 2020 Mar 17;30(11):3917-3931.e5
TXNIP deficiency mitigates podocyte apoptosis via restraining the activation of mTOR or p38 MAPK signaling in diabetic nephropathy.
Song S, Qiu D, Wang Y, Wei J, Wu H, Wu M, Wang S, Zhou X, Shi Y, Duan H
Experimental cell research 2020 Mar 15;388(2):111862
Experimental cell research 2020 Mar 15;388(2):111862
Synergetic inhibition of daidzein and regular exercise on breast cancer in bearing-4T1 mice by regulating NK cells and apoptosis pathway.
Wang B, Xu H, Hu X, Ma W, Zhang J, Li Y, Yu M, Zhang Y, Li X, Ye X
Life sciences 2020 Mar 15;245:117387
Life sciences 2020 Mar 15;245:117387
Neuronal BIN1 Regulates Presynaptic Neurotransmitter Release and Memory Consolidation.
De Rossi P, Nomura T, Andrew RJ, Masse NY, Sampathkumar V, Musial TF, Sudwarts A, Recupero AJ, Le Metayer T, Hansen MT, Shim HN, Krause SV, Freedman DJ, Bindokas VP, Kasthuri N, Nicholson DA, Contractor A, Thinakaran G
Cell reports 2020 Mar 10;30(10):3520-3535.e7
Cell reports 2020 Mar 10;30(10):3520-3535.e7
HIF2-Induced Long Noncoding RNA RAB11B-AS1 Promotes Hypoxia-Mediated Angiogenesis and Breast Cancer Metastasis.
Niu Y, Bao L, Chen Y, Wang C, Luo M, Zhang B, Zhou M, Wang JE, Fang YV, Kumar A, Xing C, Wang Y, Luo W
Cancer research 2020 Mar 1;80(5):964-975
Cancer research 2020 Mar 1;80(5):964-975
Microcystins-LR induced apoptosis via S-nitrosylation of GAPDH in colorectal cancer cells.
Li K, Huang M, Xu P, Wang M, Ye S, Wang Q, Zeng S, Chen X, Gao W, Chen J, Zhang Q, Zhong Z, Sun Y, Liu Q
Ecotoxicology and environmental safety 2020 Mar 1;190:110096
Ecotoxicology and environmental safety 2020 Mar 1;190:110096
Ferulic acid isolated from propolis inhibits porcine parvovirus replication potentially through Bid-mediate apoptosis.
Ma X, Guo Z, Zhang Z, Li X, Wang X, Liu Y, Wang X
International immunopharmacology 2020 Jun;83:106379
International immunopharmacology 2020 Jun;83:106379
Histone demethylase KDM4A regulates adipogenic and osteogenic differentiation via epigenetic regulation of C/EBPα and canonical Wnt signaling.
Qi Q, Wang Y, Wang X, Yang J, Xie Y, Zhou J, Li X, Wang B
Cellular and molecular life sciences : CMLS 2020 Jun;77(12):2407-2421
Cellular and molecular life sciences : CMLS 2020 Jun;77(12):2407-2421
ARHGEF38 as a novel biomarker to predict aggressive prostate cancer.
Liu K, Wang A, Ran L, Zhang W, Jing S, Wang Y, Zhang X, Liu G, Sen W, Song F
Genes & diseases 2020 Jun;7(2):217-224
Genes & diseases 2020 Jun;7(2):217-224
Reversing a model of Parkinson's disease with in situ converted nigral neurons.
Qian H, Kang X, Hu J, Zhang D, Liang Z, Meng F, Zhang X, Xue Y, Maimon R, Dowdy SF, Devaraj NK, Zhou Z, Mobley WC, Cleveland DW, Fu XD
Nature 2020 Jun;582(7813):550-556
Nature 2020 Jun;582(7813):550-556
MiR-153-3p induces immune dysregulation by inhibiting PELI1 expression in umbilical cord-derived mesenchymal stem cells in patients with systemic lupus erythematosus.
Li D, Li X, Duan M, Dou Y, Feng Y, Nan N, Zhang W
Autoimmunity 2020 Jun;53(4):201-209
Autoimmunity 2020 Jun;53(4):201-209
PAQR3 protects against oxygen-glucose deprivation/reperfusion-induced injury through the ERK signaling pathway in N2A cells.
Peng W, Mo X, Li L, Lu T, Hu Z
Journal of molecular histology 2020 Jun;51(3):307-315
Journal of molecular histology 2020 Jun;51(3):307-315
Clinical significance of sHER2‑ECD and calpain‑10 expression in tumor tissues of patients with breast cancer.
Ding Y, Ma M, Li Q, Gao S, Li S, Liu J, Geng C
Oncology reports 2020 Jun;43(6):2093-2104
Oncology reports 2020 Jun;43(6):2093-2104
Esculetin Ameliorates Lipopolysaccharide-Induced Acute Lung Injury in Mice Via Modulation of the AKT/ERK/NF-κB and RORγt/IL-17 Pathways.
Lee HC, Liu FC, Tsai CN, Chou AH, Liao CC, Yu HP
Inflammation 2020 Jun;43(3):962-974
Inflammation 2020 Jun;43(3):962-974
Quercetin suppresses migration and invasion by targeting miR-146a/GATA6 axis in fibroblast-like synoviocytes of rheumatoid arthritis.
Zhao J, Chen B, Peng X, Wang C, Wang K, Han F, Xu J
Immunopharmacology and immunotoxicology 2020 Jun;42(3):221-227
Immunopharmacology and immunotoxicology 2020 Jun;42(3):221-227
Inhibition of miR-574-5p suppresses cell growth and metastasis and enhances chemosensitivity by targeting RNA binding protein QKI in cervical cancer cells.
Tong R, Zhang J, Wang C, Li Q, Wang L, Ju M
Naunyn-Schmiedeberg's archives of pharmacology 2020 Jun;393(6):951-966
Naunyn-Schmiedeberg's archives of pharmacology 2020 Jun;393(6):951-966
Human placenta derived mesenchymal stromal cells alleviate GVHD by promoting the generation of GSH and GST in PD-1(+)T cells.
Zhuoya W, Nannan Z, Aiping Z, Guoyan W, Menghua D, Jiashen Z, Yanlian X, Xiying L
Cellular immunology 2020 Jun;352:104083
Cellular immunology 2020 Jun;352:104083
Regulatory T cell is critical for interleukin-33-mediated neuroprotection against stroke.
Liu X, Hu R, Pei L, Si P, Wang C, Tian X, Wang X, Liu H, Wang B, Xia Z, Xu Y, Song B
Experimental neurology 2020 Jun;328:113233
Experimental neurology 2020 Jun;328:113233
SUMOylation of vascular endothelial growth factor receptor 2 inhibits the proliferation, migration, and angiogenesis signaling pathway in non-small cell lung cancer.
Wang M, Jiang X
Anti-cancer drugs 2020 Jun;31(5):492-499
Anti-cancer drugs 2020 Jun;31(5):492-499
Tizoxanide mitigates inflammatory response in LPS-induced neuroinflammation in microglia via restraining p38/MAPK pathway.
Li XW, He RZ, Li Y, Ruan ZF
European review for medical and pharmacological sciences 2020 Jun;24(11):6446-6454
European review for medical and pharmacological sciences 2020 Jun;24(11):6446-6454
Astrocyte elevated gene 1 (AEG-1) promotes anoikis resistance and metastasis by inducing autophagy in hepatocellular carcinoma.
Zhu HD, Liu L, Deng H, Li ZB, Sheng JQ, He XX, Tian DA, Li PY
Journal of cellular physiology 2020 Jun;235(6):5084-5095
Journal of cellular physiology 2020 Jun;235(6):5084-5095
Disregulation of Autophagy in the Transgenerational Cc2d1a Mouse Model of Autism.
Dana H, Bayramov KK, Delibaşı N, Tahtasakal R, Bayramov R, Hamurcu Z, Sener EF
Neuromolecular medicine 2020 Jun;22(2):239-249
Neuromolecular medicine 2020 Jun;22(2):239-249
The Activation of Heat-Shock Protein After Copper(II) and/or Arsenic(III)-Induced Imbalance of Homeostasis, Inflammatory Response in Chicken Rectum.
Yang X, Zhao H, Wang Y, Liu J, Guo M, Fei D, Mu M, Xing M
Biological trace element research 2020 Jun;195(2):613-623
Biological trace element research 2020 Jun;195(2):613-623
BRM-SWI/SNF chromatin remodeling complex enables functional telomeres by promoting co-expression of TRF2 and TRF1.
Wu S, Ge Y, Li X, Yang Y, Zhou H, Lin K, Zhang Z, Zhao Y
PLoS genetics 2020 Jun;16(6):e1008799
PLoS genetics 2020 Jun;16(6):e1008799
Sustained mitochondrial biogenesis is essential to maintain caloric restriction-induced beige adipocytes.
Mooli RGR, Mukhi D, Watt M, Edmunds L, Xie B, Capooci J, Reslink M, Eze C, Mills A, Stolz DB, Jurczak M, Ramakrishnan SK
Metabolism: clinical and experimental 2020 Jun;107:154225
Metabolism: clinical and experimental 2020 Jun;107:154225
Tolfenamic acid inhibits GSK-3β and PP2A mediated tau hyperphosphorylation in Alzheimer's disease models.
Zhang H, Wang X, Xu P, Ji X, Chi T, Liu P, Zou L
The journal of physiological sciences : JPS 2020 Jun 9;70(1):29
The journal of physiological sciences : JPS 2020 Jun 9;70(1):29
Highly expressed STAT1 contributes to the suppression of stemness properties in human paclitaxel-resistant ovarian cancer cells.
Wang F, Zhang L, Liu J, Zhang J, Xu G
Aging 2020 Jun 9;12(11):11042-11060
Aging 2020 Jun 9;12(11):11042-11060
Arsenic induces dysfunctional autophagy via dual regulation of mTOR pathway and Beclin1-Vps34/PI3K complex in MLTC-1 cells.
Liang C, Feng Z, Manthari RK, Wang C, Han Y, Fu W, Wang J, Zhang J
Journal of hazardous materials 2020 Jun 5;391:122227
Journal of hazardous materials 2020 Jun 5;391:122227
The GTPase Rab27b regulates the release, autophagic clearance, and toxicity of α-synuclein.
Underwood R, Wang B, Carico C, Whitaker RH, Placzek WJ, Yacoubian TA
The Journal of biological chemistry 2020 Jun 5;295(23):8005-8016
The Journal of biological chemistry 2020 Jun 5;295(23):8005-8016
BDH2 triggers ROS-induced cell death and autophagy by promoting Nrf2 ubiquitination in gastric cancer.
Liu JZ, Hu YL, Feng Y, Jiang Y, Guo YB, Liu YF, Chen X, Yang JL, Chen YY, Mao QS, Xue WJ
Journal of experimental & clinical cancer research : CR 2020 Jun 30;39(1):123
Journal of experimental & clinical cancer research : CR 2020 Jun 30;39(1):123
Enterovirus A71 Oncolysis of Malignant Gliomas.
Zhang X, Wang H, Sun Y, Qi M, Li W, Zhang Z, Zhang XE, Cui Z
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Jun 3;28(6):1533-1546
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Jun 3;28(6):1533-1546
Cytoplasmic PCNA is located in the actin belt and involved in osteoclast differentiation.
Tang D, Liu X, Chen K, Li Z, Dai Y, Xu J, Zhang HT, Gao X, Liu L
Aging 2020 Jun 27;12(13):13297-13317
Aging 2020 Jun 27;12(13):13297-13317
MiR-377-3p inhibits atherosclerosis-associated vascular smooth muscle cell proliferation and migration via targeting neuropilin2.
Wang H, Wei Z, Li H, Guan Y, Han Z, Wang H, Liu B
Bioscience reports 2020 Jun 26;40(6)
Bioscience reports 2020 Jun 26;40(6)
Molecular mechanism of targeted inhibition of HMGA2 via miRNAlet-7a in proliferation and metastasis of laryngeal squamous cell carcinoma.
Ma LJ, Wu J, Zhou E, Yin J, Xiao XP
Bioscience reports 2020 Jun 26;40(6)
Bioscience reports 2020 Jun 26;40(6)
Opening large-conductance potassium channels selectively induced cell death of triple-negative breast cancer.
Sizemore G, McLaughlin S, Newman M, Brundage K, Ammer A, Martin K, Pugacheva E, Coad J, Mattes MD, Yu HG
BMC cancer 2020 Jun 26;20(1):595
BMC cancer 2020 Jun 26;20(1):595
Enhanced autophagic retrograde axonal transport by dynein intermediate chain upregulation improves Aβ clearance and cognitive function in APP/PS1 double transgenic mice.
Zhou F, Xiong X, Li S, Liang J, Zhang X, Tian M, Li X, Gao M, Tang L, Li Y
Aging 2020 Jun 24;12(12):12142-12159
Aging 2020 Jun 24;12(12):12142-12159
L-3-n-butylphthalide attenuates inflammation response and brain edema in rat intracerebral hemorrhage model.
Zeng Z, Gong X, Hu Z
Aging 2020 Jun 21;12(12):11768-11780
Aging 2020 Jun 21;12(12):11768-11780
A Gold(I) Complex Containing an Oleanolic Acid Derivative as a Potential Anti-Ovarian-Cancer Agent by Inhibiting TrxR and Activating ROS-Mediated ERS.
Bian M, Sun Y, Liu Y, Xu Z, Fan R, Liu Z, Liu W
Chemistry (Weinheim an der Bergstrasse, Germany) 2020 Jun 2;26(31):7092-7108
Chemistry (Weinheim an der Bergstrasse, Germany) 2020 Jun 2;26(31):7092-7108
Excretory/secretory products of Angiostrongylus cantonensis fifth-stage larvae induce endoplasmic reticulum stress via the Sonic hedgehog pathway in mouse astrocytes.
Chen KY, Chen YJ, Cheng CJ, Jhan KY, Wang LC
Parasites & vectors 2020 Jun 18;13(1):317
Parasites & vectors 2020 Jun 18;13(1):317
Immune profiling reveals prognostic genes in high-grade serous ovarian cancer.
Wu Y, Xia L, Zhao P, Deng Y, Guo Q, Zhu J, Chen X, Ju X, Wu X
Aging 2020 Jun 16;12(12):11398-11415
Aging 2020 Jun 16;12(12):11398-11415
Neurotoxicity of aluminum oxide nanoparticles and their mechanistic role in dopaminergic neuron injury involving p53-related pathways.
Liu H, Zhang W, Fang Y, Yang H, Tian L, Li K, Lai W, Bian L, Lin B, Liu X, Xi Z
Journal of hazardous materials 2020 Jun 15;392:122312
Journal of hazardous materials 2020 Jun 15;392:122312
Cerenkov luminescence imaging is an effective preclinical tool for assessing colorectal cancer PD-L1 levels in vivo.
Zhao S, Pan W, Jiang H, Zhang R, Jiang H, Liang Z, Hu H
EJNMMI research 2020 Jun 15;10(1):64
EJNMMI research 2020 Jun 15;10(1):64
Mechanism of Heshouwuyin inhibiting the Cyt c/Apaf-1/Caspase-9/Caspase-3 pathway in spermatogenic cell apoptosis.
Wang H, Zhu J, Jiang L, Shan B, Xiao P, Ai J, Li N, Qi F, Niu S
BMC complementary medicine and therapies 2020 Jun 11;20(1):180
BMC complementary medicine and therapies 2020 Jun 11;20(1):180
Regulatory effects of Prohibitin 1 on proliferation and apoptosis of pulmonary arterial smooth muscle cells in monocrotaline-induced PAH rats.
Cao YY, Ba HX, Li Y, Tang SY, Luo ZQ, Li XH
Life sciences 2020 Jun 1;250:117548
Life sciences 2020 Jun 1;250:117548
Synergistic Effect of Benzethonium Chloride Combined with Endoxan against Hepatocellular Carcinoma in Rats through Targeting Apoptosis Signaling Pathway.
Abozaid OAR, Moawed FSM, Farrag MA, Kawara RSM
Asian Pacific journal of cancer prevention : APJCP 2020 Jun 1;21(6):1709-1716
Asian Pacific journal of cancer prevention : APJCP 2020 Jun 1;21(6):1709-1716
Fast and unbiased purification of RNA-protein complexes after UV cross-linking.
Urdaneta EC, Beckmann BM
Methods (San Diego, Calif.) 2020 Jun 1;178:72-82
Methods (San Diego, Calif.) 2020 Jun 1;178:72-82
Daucosterol linolenate from Sweet Potato Suppresses MCF7-Xenograft-Tumor Growth through Regulating PI3K/AKT Pathway.
Han B, Jiang L, Jiang P, Zhou D, Jia X, Li X, Ye X
Planta medica 2020 Jul;86(11):767-775
Planta medica 2020 Jul;86(11):767-775
A novel homozygous nonsense ZP1 variant causes human female infertility associated with empty follicle syndrome (EFS).
Xu Q, Zhu X, Maqsood M, Li W, Tong X, Kong S, Wang F, Liu X, Wei Z, Zhang Z, Zhu F, Cao Y, Bao J
Molecular genetics & genomic medicine 2020 Jul;8(7):e1269
Molecular genetics & genomic medicine 2020 Jul;8(7):e1269
Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation.
Chen Z, Li Z, Hu X, Xie F, Kuang S, Zhan B, Gao W, Chen X, Gao S, Li Y, Wang Y, Qian F, Ding C, Gan J, Ji C, Xu XW, Zhou Z, Huang J, He HH, Li J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2020 Jul;7(14):2000532
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2020 Jul;7(14):2000532
A mitophagic response to iron overload-induced oxidative damage associated with the PINK1/Parkin pathway in pancreatic beta cells.
Zhang L, Hou L, Liu Z, Huang S, Meng Z, Liang L
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2020 Jul;60:126493
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2020 Jul;60:126493
lncRNA LA16c‑313D11.11 modulates the development of endometrial cancer by binding to and inhibiting microRNA‑205‑5p function and indirectly increasing PTEN activity.
Xin W, Zhao S, Han X, Zhao P, Yu H, Gao X, Li P, Wu Q, Ding J, Hua K
International journal of oncology 2020 Jul;57(1):355-363
International journal of oncology 2020 Jul;57(1):355-363
Matrix Metalloproteinase 11 as a Novel Tumor Promoter and Diagnostic and Prognostic Biomarker for Pancreatic Ductal Adenocarcinoma.
Zhang X, Lu J, Zhou L, You L, Liang Z, Guo J, Zhao Y
Pancreas 2020 Jul;49(6):812-821
Pancreas 2020 Jul;49(6):812-821
Characterization of red ginseng-drug interaction by CYP3A activity increased in high dose administration in mice.
Kim Y, Jo JJ, Cho P, Shrestha R, Kim KM, Ki SH, Song KS, Liu KH, Song IS, Kim JH, Lee JM, Lee S
Biopharmaceutics & drug disposition 2020 Jul;41(7):295-306
Biopharmaceutics & drug disposition 2020 Jul;41(7):295-306
HMGB1-induced aberrant autophagy contributes to insulin resistance in granulosa cells in PCOS.
Zhang C, Hu J, Wang W, Sun Y, Sun K
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jul;34(7):9563-9574
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jul;34(7):9563-9574
miR-196b-5p controls adipocyte differentiation and lipogenesis through regulating mTORC1 and TGF-β signaling.
Shi Y, Li F, Wang S, Wang C, Xie Y, Zhou J, Li X, Wang B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jul;34(7):9207-9222
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jul;34(7):9207-9222
Presynaptic Caytaxin prevents apoptosis via deactivating DAPK1 in the acute phase of cerebral ischemic stroke.
Wang S, Chen K, Yu J, Wang X, Li Q, Lv F, Shen H, Pei L
Experimental neurology 2020 Jul;329:113303
Experimental neurology 2020 Jul;329:113303
miR-203a suppresses cell proliferation by targeting RING-finger protein 6 in colorectal cancer.
Miao J, Hou N, Yang W, Jiang Q, Xue W, Wang X, Zhang H, Xiong X, Wang L, Zhao L, Huang C
Anti-cancer drugs 2020 Jul;31(6):583-591
Anti-cancer drugs 2020 Jul;31(6):583-591
Stomatin-like protein-2 confers neuroprotection effect in oxygen-glucose deprivation/reoxygenation-injured neurons by regulating AMPK/Nrf2 signalling.
Wang M, Li C, Shi W
Journal of drug targeting 2020 Jul;28(6):600-608
Journal of drug targeting 2020 Jul;28(6):600-608
Protective effect of quercetin on rat testes against cadmium toxicity by alleviating oxidative stress and autophagy.
Wang J, Zhu H, Wang K, Yang Z, Liu Z
Environmental science and pollution research international 2020 Jul;27(20):25278-25286
Environmental science and pollution research international 2020 Jul;27(20):25278-25286
BMP7 is Downregulated in Lumbosacral Spinal Cord of Rat Embryos With Anorectal Malformation.
Yang Z, Li X, Jia H, Bai Y, Wang W
The Journal of surgical research 2020 Jul;251:202-210
The Journal of surgical research 2020 Jul;251:202-210
Targeted immunomodulation of inflammatory monocytes across the blood-brain barrier by curcumin-loaded nanoparticles delays the progression of experimental autoimmune encephalomyelitis.
Lu L, Qi S, Chen Y, Luo H, Huang S, Yu X, Luo Q, Zhang Z
Biomaterials 2020 Jul;245:119987
Biomaterials 2020 Jul;245:119987
AMPH1 functions as a tumour suppressor in ovarian cancer via the inactivation of PI3K/AKT pathway.
Chen Y, Cao W, Wang L, Zhong T
Journal of cellular and molecular medicine 2020 Jul;24(13):7652-7659
Journal of cellular and molecular medicine 2020 Jul;24(13):7652-7659
SIRT2 suppresses expression of inflammatory factors via Hsp90-glucocorticoid receptor signalling.
Sun K, Wang X, Fang N, Xu A, Lin Y, Zhao X, Nazarali AJ, Ji S
Journal of cellular and molecular medicine 2020 Jul;24(13):7439-7450
Journal of cellular and molecular medicine 2020 Jul;24(13):7439-7450
CUDC-907, a novel dual PI3K and HDAC inhibitor, in prostate cancer: Antitumour activity and molecular mechanism of action.
Hu C, Xia H, Bai S, Zhao J, Edwards H, Li X, Yang Y, Lyu J, Wang G, Zhan Y, Dong Y, Ge Y
Journal of cellular and molecular medicine 2020 Jul;24(13):7239-7253
Journal of cellular and molecular medicine 2020 Jul;24(13):7239-7253
The effect of lncRNA-ARAP1-AS2/ARAP1 on high glucose-induced cytoskeleton rearrangement and epithelial-mesenchymal transition in human renal tubular epithelial cells.
Li L, Xu L, Wen S, Yang Y, Li X, Fan Q
Journal of cellular physiology 2020 Jul;235(7-8):5787-5795
Journal of cellular physiology 2020 Jul;235(7-8):5787-5795
Reversal of prolonged obesity-associated cerebrovascular dysfunction by inhibiting microglial Tak1.
Shen Q, Chen Z, Zhao F, Pan S, Zhang T, Cheng X, Zhang L, Zhang S, Qi J, Li J, Cai D, Zhang G
Nature neuroscience 2020 Jul;23(7):832-841
Nature neuroscience 2020 Jul;23(7):832-841
LHPP inhibits hepatocellular carcinoma cell growth and metastasis.
Liao L, Duan D, Liu Y, Chen L
Cell cycle (Georgetown, Tex.) 2020 Jul;19(14):1846-1854
Cell cycle (Georgetown, Tex.) 2020 Jul;19(14):1846-1854
Melatonin protects against chronic stress-induced oxidative meiotic defects in mice MII oocytes by regulating SIRT1.
Guo Y, Sun J, Bu S, Li B, Zhang Q, Wang Q, Lai D
Cell cycle (Georgetown, Tex.) 2020 Jul;19(13):1677-1695
Cell cycle (Georgetown, Tex.) 2020 Jul;19(13):1677-1695
Human alkaline ceramidase 2 promotes the growth, invasion, and migration of hepatocellular carcinoma cells via sphingomyelin phosphodiesterase acid-like 3B.
Liu B, Xiao J, Dong M, Qiu Z, Jin J
Cancer science 2020 Jul;111(7):2259-2274
Cancer science 2020 Jul;111(7):2259-2274
Bisdemethoxycurcumin inhibits oxidative stress and antagonizes Alzheimer's disease by up-regulating SIRT1.
Xu Y, Hu R, He D, Zhou G, Wu H, Xu C, He B, Wu L, Wang Y, Chang Y, Ma R, Xie M, Xiao Z
Brain and behavior 2020 Jul;10(7):e01655
Brain and behavior 2020 Jul;10(7):e01655
Pathological mutations in PNKP trigger defects in DNA single-strand break repair but not DNA double-strand break repair.
Kalasova I, Hailstone R, Bublitz J, Bogantes J, Hofmann W, Leal A, Hanzlikova H, Caldecott KW
Nucleic acids research 2020 Jul 9;48(12):6672-6684
Nucleic acids research 2020 Jul 9;48(12):6672-6684
Integrative Proteomic Characterization of Human Lung Adenocarcinoma.
Xu JY, Zhang C, Wang X, Zhai L, Ma Y, Mao Y, Qian K, Sun C, Liu Z, Jiang S, Wang M, Feng L, Zhao L, Liu P, Wang B, Zhao X, Xie H, Yang X, Zhao L, Chang Y, Jia J, Wang X, Zhang Y, Wang Y, Yang Y, Wu Z, Yang L, Liu B, Zhao T, Ren S, Sun A, Zhao Y, Ying W, Wang F, Wang G, Zhang Y, Cheng S, Qin J, Qian X, Wang Y, Li J, He F, Xiao T, Tan M
Cell 2020 Jul 9;182(1):245-261.e17
Cell 2020 Jul 9;182(1):245-261.e17
SLC7A2 serves as a potential biomarker and therapeutic target for ovarian cancer.
Sun T, Bi F, Liu Z, Yang Q
Aging 2020 Jul 9;12(13):13281-13296
Aging 2020 Jul 9;12(13):13281-13296
Protective effect of miRNA-containing extracellular vesicles derived from mesenchymal stromal cells of old rats on renal function in chronic kidney disease.
Wang Y, Guo YF, Fu GP, Guan C, Zhang X, Yang DG, Shi YC
Stem cell research & therapy 2020 Jul 8;11(1):274
Stem cell research & therapy 2020 Jul 8;11(1):274
SNHG11 promotes cell proliferation in colorectal cancer by forming a positive regulatory loop with c-Myc.
Huang W, Dong S, Cha Y, Yuan X
Biochemical and biophysical research communications 2020 Jul 5;527(4):985-992
Biochemical and biophysical research communications 2020 Jul 5;527(4):985-992
The miR-1224-5p/TNS4/EGFR axis inhibits tumour progression in oesophageal squamous cell carcinoma.
Shi ZZ, Wang WJ, Chen YX, Fan ZW, Xie XF, Yang LY, Chang C, Cai Y, Hao JJ, Wang MR, Bai J
Cell death & disease 2020 Jul 30;11(7):597
Cell death & disease 2020 Jul 30;11(7):597
Transcriptome Analysis of Testes and Uterus: Reproductive Dysfunction Induced by Toxoplasma gondii in Mice.
Wang J, Liu T, Mahmmod YS, Yang Z, Tan J, Ren Z, Zhang X, Yang X, Zhang XX, Yuan ZG
Microorganisms 2020 Jul 28;8(8)
Microorganisms 2020 Jul 28;8(8)
NLRP3 inflammasome-mediated microglial pyroptosis is critically involved in the development of post-cardiac arrest brain injury.
Chang Y, Zhu J, Wang D, Li H, He Y, Liu K, Wang X, Peng Y, Pan S, Huang K
Journal of neuroinflammation 2020 Jul 23;17(1):219
Journal of neuroinflammation 2020 Jul 23;17(1):219
Innate Effector Systems in Primary Human Macrophages Sensitize Multidrug-Resistant Klebsiella pneumoniae to Antibiotics.
Rekha RS, Karadottir H, Ahmed S, Gudmundsson GH, Agerberth B, Bergman P
Infection and immunity 2020 Jul 21;88(8)
Infection and immunity 2020 Jul 21;88(8)
ZIC2 is downregulated and represses tumor growth via the regulation of STAT3 in breast cancer.
Liu ZH, Chen ML, Zhang Q, Zhang Y, An X, Luo YL, Liu XM, Liu SX, Liu Q, Yang T, Liu YM, Liu BL, Zhou AJ, Li MZ, Liu YJ, Liu ZX, Zhong Q
International journal of cancer 2020 Jul 15;147(2):505-518
International journal of cancer 2020 Jul 15;147(2):505-518
Impairment in dynein-mediated nuclear translocation by BICD2 C-terminal truncation leads to neuronal migration defect and human brain malformation.
Tsai MH, Cheng HY, Nian FS, Liu C, Chao NH, Chiang KL, Chen SF, Tsai JW
Acta neuropathologica communications 2020 Jul 14;8(1):106
Acta neuropathologica communications 2020 Jul 14;8(1):106
Genetic variants in m6A modification genes are associated with esophageal squamous-cell carcinoma in the Chinese population.
Yang N, Ying P, Tian J, Wang X, Mei S, Zou D, Peng X, Gong Y, Yang Y, Zhu Y, Ke J, Zhong R, Chang J, Miao X
Carcinogenesis 2020 Jul 10;41(6):761-768
Carcinogenesis 2020 Jul 10;41(6):761-768
Long non-coding RNA JPX correlates with poor prognosis and tumor progression in non-small-cell lung cancer by interacting with miR-145-5p and CCND2.
Jin M, Ren J, Luo M, You Z, Fang Y, Han Y, Li G, Liu H
Carcinogenesis 2020 Jul 10;41(5):634-645
Carcinogenesis 2020 Jul 10;41(5):634-645
Excessive Mg(2+) Impairs Intestinal Homeostasis by Enhanced Production of Adenosine Triphosphate and Reactive Oxygen Species.
Hashizume O, Funato Y, Yamazaki D, Miki H
Antioxidants & redox signaling 2020 Jul 1;33(1):20-34
Antioxidants & redox signaling 2020 Jul 1;33(1):20-34
Carfilzomib inhibits the growth of lung adenocarcinoma via upregulation of Gadd45a expression.
Yang F, Liu WW, Chen H, Zhu J, Huang AH, Zhou F, Gan Y, Zhang YH, Ma L
Journal of Zhejiang University. Science. B 2020 Jan.;21(1):64-76
Journal of Zhejiang University. Science. B 2020 Jan.;21(1):64-76
Identification and characterization of c-raf from orange-spotted grouper (Epinephelus coioides).
Mo ZQ, Lai XL, Wang WT, Chen HP, He ZC, Han R, Wang JL, Luo XC, Li YW, Dan XM
Fish & shellfish immunology 2020 Jan;96:311-318
Fish & shellfish immunology 2020 Jan;96:311-318
MiR-203a-3p inhibits retinal angiogenesis and alleviates proliferative diabetic retinopathy in oxygen-induced retinopathy (OIR) rat model via targeting VEGFA and HIF-1α.
Han N, Xu H, Yu N, Wu Y, Yu L
Clinical and experimental pharmacology & physiology 2020 Jan;47(1):85-94
Clinical and experimental pharmacology & physiology 2020 Jan;47(1):85-94
Calycosin-7-O-β-D-glucoside attenuates myocardial ischemia-reperfusion injury by activating JAK2/STAT3 signaling pathway via the regulation of IL-10 secretion in mice.
Liu Y, Che G, Di Z, Sun W, Tian J, Ren M
Molecular and cellular biochemistry 2020 Jan;463(1-2):175-187
Molecular and cellular biochemistry 2020 Jan;463(1-2):175-187
MiR-183-5p protects rat hearts against myocardial ischemia/reperfusion injury through targeting VDAC1.
Lin D, Cui B, Ma J, Ren J
BioFactors (Oxford, England) 2020 Jan;46(1):83-93
BioFactors (Oxford, England) 2020 Jan;46(1):83-93
Decreased ALCAM expression and promoter hypermethylation is associated with preeclampsia.
Wei LL, Pan YS, Tang Q, Yang ZJ, Song WQ, Gao YF, Li J, Zhang L, Liu SG
Hypertension research : official journal of the Japanese Society of Hypertension 2020 Jan;43(1):13-22
Hypertension research : official journal of the Japanese Society of Hypertension 2020 Jan;43(1):13-22
High Expression of c-Met, PKCλ and ALDH1A3 Predicts a Poor Prognosis in Late-stage Breast Cancer.
Motomura H, Nozaki Y, Onaga C, Ozaki A, Tamori S, Shiina TA, Kanai S, Ohira C, Hara Y, Harada Y, Takasawa R, Hanawa T, Tanuma SI, Mano Y, Sato T, Sato K, Akimoto K
Anticancer research 2020 Jan;40(1):35-52
Anticancer research 2020 Jan;40(1):35-52
ALK(ATI) interacts with c-Myc and promotes cancer stem cell-like properties in sarcoma.
Xu BS, Chen HY, Que Y, Xiao W, Zeng MS, Zhang X
Oncogene 2020 Jan;39(1):151-163
Oncogene 2020 Jan;39(1):151-163
MnTBAP inhibits bone loss in ovariectomized rats by reducing mitochondrial oxidative stress in osteoblasts.
Cao X, Luo D, Li T, Huang Z, Zou W, Wang L, Lian K, Lin D
Journal of bone and mineral metabolism 2020 Jan;38(1):27-37
Journal of bone and mineral metabolism 2020 Jan;38(1):27-37
LncRNA SNHG3 promotes cell proliferation and invasion through the miR-384/hepatoma-derived growth factor axis in breast cancer.
Ma Q, Qi X, Lin X, Li L, Chen L, Hu W
Human cell 2020 Jan;33(1):232-242
Human cell 2020 Jan;33(1):232-242
Hydrogen sulfide attenuates cigarette smoke-induced airway remodeling by upregulating SIRT1 signaling pathway.
Guan R, Wang J, Cai Z, Li Z, Wang L, Li Y, Xu J, Li D, Yao H, Liu W, Deng B, Lu W
Redox biology 2020 Jan;28:101356
Redox biology 2020 Jan;28:101356
Human mesenchymal stem cells-derived conditioned medium inhibits hypoxia-induced death of neonatal porcine islets by inducing autophagy.
Xu Y, Tan M, Ma X, Li H, He X, Chen Z, Tan Y, Nie W, Rong P, Wang W
Xenotransplantation 2020 Jan;27(1):e12556
Xenotransplantation 2020 Jan;27(1):e12556
LncRNA HOXA11-AS regulates calcium oxalate crystal-induced renal inflammation via miR-124-3p/MCP-1.
Li Y, Yan G, Zhang J, Chen W, Ding T, Yin Y, Li M, Zhu Y, Sun S, Yuan JH, Guo Z
Journal of cellular and molecular medicine 2020 Jan;24(1):238-249
Journal of cellular and molecular medicine 2020 Jan;24(1):238-249
Arsenic influences spermatogenesis by disorganizing the elongation of spermatids in adult male mice.
Han Y, Liang C, Manthari RK, Yu Y, Gao Y, Liu Y, Jiang S, Tikka C, Wang J, Zhang J
Chemosphere 2020 Jan;238:124650
Chemosphere 2020 Jan;238:124650
Endoplasmic reticulum stress regulates epithelial‑mesenchymal transition in human lens epithelial cells.
Zhou S, Yang J, Wang M, Zheng D, Liu Y
Molecular medicine reports 2020 Jan;21(1):173-180
Molecular medicine reports 2020 Jan;21(1):173-180
Effects of oral florfenicol on intestinal structure, function and microbiota in mice.
Yun S, Guo Y, Yang L, Zhang X, Shen W, Wang Z, Wen S, Zhao D, Wu H, Chen J, Sun Y, Duan Z
Archives of microbiology 2020 Jan;202(1):161-169
Archives of microbiology 2020 Jan;202(1):161-169
MicroRNA-138 inhibits tumor growth and enhances chemosensitivity in human cervical cancer by targeting H2AX.
Yuan M, Zhao S, Chen R, Wang G, Bie Y, Wu Q, Cheng J
Experimental and therapeutic medicine 2020 Jan;19(1):630-638
Experimental and therapeutic medicine 2020 Jan;19(1):630-638
REDD1 overexpression in oral squamous cell carcinoma may predict poor prognosis and correlates with high microvessel density.
Feng Y, Song K, Shang W, Chen L, Wang C, Pang B, Wang N
Oncology letters 2020 Jan;19(1):431-441
Oncology letters 2020 Jan;19(1):431-441
USP12 translocation maintains interferon antiviral efficacy by inhibiting CBP acetyltransferase activity.
Liu J, Jin L, Chen X, Yuan Y, Zuo Y, Miao Y, Feng Q, Zhang H, Huang F, Guo T, Zhang L, Zhu L, Qian F, Zhu C, Zheng H
PLoS pathogens 2020 Jan;16(1):e1008215
PLoS pathogens 2020 Jan;16(1):e1008215
The novel thioredoxin reductase inhibitor A-Z2 triggers intrinsic apoptosis and shows efficacy in the treatment of acute myeloid leukemia.
Zhang D, Liu Y, Luo Z, Chen Y, Xu A, Liang Y, Wu B, Tong X, Liu X, Shen H, Liu L, Wei Y, Zhou H, Liu Y, Zhou F
Free radical biology & medicine 2020 Jan;146:275-286
Free radical biology & medicine 2020 Jan;146:275-286
Osthole inhibits cell proliferation by regulating the TGF-β1/Smad/p38 signaling pathways in pulmonary arterial smooth muscle cells.
Yue Y, Li YQ, Fu S, Wu YT, Zhu L, Hua L, Lv JY, Li YL, Yang DL
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109640
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109640
Tandem mass tag (TMT) proteomic analysis of fetal lungs revealed differential expression of tight junction proteins in a rat model of congenital diaphragmatic hernia.
Li X, Liu H, Yu W, Liu X, Liu C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109621
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109621
Activation of CD137 signaling promotes neointimal formation by attenuating TET2 and transferrring from endothelial cell-derived exosomes to vascular smooth muscle cells.
Li B, Zang G, Zhong W, Chen R, Zhang Y, Yang P, Yan J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109593
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109593
LncRNA GAS5 exacerbates renal tubular epithelial fibrosis by acting as a competing endogenous RNA of miR-96-5p.
Wang W, Jia YJ, Yang YL, Xue M, Zheng ZJ, Wang L, Xue YM
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109411
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109411
Isolated Erythrocytosis Associated With 3 Novel Missense Mutations in the EGLN1 Gene.
Moore JA, Hubbi ME, Wang C, Wang Y, Luo W, Hofmann S, Rambally S
Journal of investigative medicine high impact case reports 2020 Jan-Dec;8:2324709620947256
Journal of investigative medicine high impact case reports 2020 Jan-Dec;8:2324709620947256
Acetyltransferase GCN5 regulates autophagy and lysosome biogenesis by targeting TFEB.
Wang Y, Huang Y, Liu J, Zhang J, Xu M, You Z, Peng C, Gong Z, Liu W
EMBO reports 2020 Jan 7;21(1):e48335
EMBO reports 2020 Jan 7;21(1):e48335
5-(3,4,5-trimethoxybenzoyl)-4-methyl-2-(p-tolyl) imidazol (BZML) targets tubulin and DNA to induce anticancer activity and overcome multidrug resistance in colorectal cancer cells.
Bai Z, Liu X, Guan Q, Ding N, Wei Q, Tong B, Zhao M, Zhang W, Ma L
Chemico-biological interactions 2020 Jan 5;315:108886
Chemico-biological interactions 2020 Jan 5;315:108886
Resveratrol targets PD-L1 glycosylation and dimerization to enhance antitumor T-cell immunity.
Verdura S, Cuyàs E, Cortada E, Brunet J, Lopez-Bonet E, Martin-Castillo B, Bosch-Barrera J, Encinar JA, Menendez JA
Aging 2020 Jan 4;12(1):8-34
Aging 2020 Jan 4;12(1):8-34
The tight junction protein TJP1 regulates the feeding-modulated hepatic circadian clock.
Liu Y, Zhang Y, Li T, Han J, Wang Y
Nature communications 2020 Jan 30;11(1):589
Nature communications 2020 Jan 30;11(1):589
Porphyromonas gingivalis triggers inflammatory responses in periodontal ligament cells by succinate-succinate dehydrogenase-HIF-1α axis.
Su W, Shi J, Zhao Y, Yan F, Lei L, Li H
Biochemical and biophysical research communications 2020 Jan 29;522(1):184-190
Biochemical and biophysical research communications 2020 Jan 29;522(1):184-190
Alisol A-24-acetate promotes glucose uptake via activation of AMPK in C2C12 myotubes.
Chen JX, Li HY, Li TT, Fu WC, Du X, Liu CH, Zhang W
BMC complementary medicine and therapies 2020 Jan 29;20(1):22
BMC complementary medicine and therapies 2020 Jan 29;20(1):22
Schnurri-3 regulates BMP9-induced osteogenic differentiation and angiogenesis of human amniotic mesenchymal stem cells through Runx2 and VEGF.
Li Y, Liu Z, Tang Y, Feng W, Zhao C, Liao J, Zhang C, Chen H, Ren Y, Dong S, Liu Y, Hu N, Huang W
Cell death & disease 2020 Jan 29;11(1):72
Cell death & disease 2020 Jan 29;11(1):72
Calcium relieves fluoride-induced bone damage through the PI3K/AKT pathway.
Wang J, Xu H, Cheng X, Yang J, Yan Z, Ma H, Zhao Y, Ommati MM, Manthari RK, Wang J
Food & function 2020 Jan 29;11(1):1155-1164
Food & function 2020 Jan 29;11(1):1155-1164
Graphene Oxide Promotes Cancer Metastasis through Associating with Plasma Membrane To Promote TGF-β Signaling-Dependent Epithelial-Mesenchymal Transition.
Zhu J, Li B, Xu M, Liu R, Xia T, Zhang Z, Xu Y, Liu S
ACS nano 2020 Jan 28;14(1):818-827
ACS nano 2020 Jan 28;14(1):818-827
GSPE alleviates renal fibrosis by inhibiting the activation of C3/ HMGB1/ TGF-β1 pathway.
Wang K, Wei H, Zhan J, Liang X, Zhang C, Liu Y, Xu G
Chemico-biological interactions 2020 Jan 25;316:108926
Chemico-biological interactions 2020 Jan 25;316:108926
An insertion mutation of ERBB2 enhances breast cancer cell growth and confers resistance to lapatinib through AKT signaling pathway.
Yang ZY, Yang L, Xu CW, Wang XJ, Lei L
Biology open 2020 Jan 24;9(1)
Biology open 2020 Jan 24;9(1)
miR-485 suppresses inflammation and proliferation of mesangial cells in an in vitro model of diabetic nephropathy by targeting NOX5.
Wu J, Lu K, Zhu M, Xie X, Ding Y, Shao X, Chen Y, Liu J, Xu M, Xu Y, Zhou J, Shen X, Zhu C
Biochemical and biophysical research communications 2020 Jan 22;521(4):984-990
Biochemical and biophysical research communications 2020 Jan 22;521(4):984-990
FAM60A, increased by Helicobacter pylori, promotes proliferation and suppresses apoptosis of gastric cancer cells by targeting the PI3K/AKT pathway.
Yao X, Liu D, Zhou L, Xie Y, Li Y
Biochemical and biophysical research communications 2020 Jan 22;521(4):1003-1009
Biochemical and biophysical research communications 2020 Jan 22;521(4):1003-1009
A protective role of renalase in diabetic nephropathy.
Yin J, Liu X, Zhao T, Liang R, Wu R, Zhang F, Kong Y, Liu L, Xing T, Wang N, Zhao Q, Wang F
Clinical science (London, England : 1979) 2020 Jan 17;134(1):75-85
Clinical science (London, England : 1979) 2020 Jan 17;134(1):75-85
The Nuclear Matrix Protein SAFB Cooperates with Major Satellite RNAs to Stabilize Heterochromatin Architecture Partially through Phase Separation.
Huo X, Ji L, Zhang Y, Lv P, Cao X, Wang Q, Yan Z, Dong S, Du D, Zhang F, Wei G, Liu Y, Wen B
Molecular cell 2020 Jan 16;77(2):368-383.e7
Molecular cell 2020 Jan 16;77(2):368-383.e7
Effects of a natural PTP1B inhibitor from Rhodomela confervoides on the amelioration of fatty acid-induced insulin resistance in hepatocytes and hyperglycaemia in STZ-induced diabetic rats.
Guo S, Wang L, Chen D, Jiang B
RSC advances 2020 Jan 16;10(6):3429-3437
RSC advances 2020 Jan 16;10(6):3429-3437
K562 cell-derived exosomes suppress the adhesive function of bone marrow mesenchymal stem cells via delivery of miR-711.
Jiang YH, Liu J, Lin J, Li SQ, Xu YM, Min QH, Zhong QH, Sun F, Li J, You XH, Liao KL, Qin TY, Zhao C, Huang B, Wang XZ
Biochemical and biophysical research communications 2020 Jan 15;521(3):584-589
Biochemical and biophysical research communications 2020 Jan 15;521(3):584-589
Fangchinoline derivatives induce cell cycle arrest and apoptosis in human leukemia cell lines via suppression of the PI3K/AKT and MAPK signaling pathway.
Yang J, Hu S, Wang C, Song J, Chen C, Fan Y, Ben-David Y, Pan W
European journal of medicinal chemistry 2020 Jan 15;186:111898
European journal of medicinal chemistry 2020 Jan 15;186:111898
Microglia P2X4R-BDNF signalling contributes to central sensitization in a recurrent nitroglycerin-induced chronic migraine model.
Long T, He W, Pan Q, Zhang S, Zhang D, Qin G, Chen L, Zhou J
The journal of headache and pain 2020 Jan 14;21(1):4
The journal of headache and pain 2020 Jan 14;21(1):4
DEF Cell-Derived Exosomal miR-148a-5p Promotes DTMUV Replication by Negative Regulating TLR3 Expression.
Guo H, Cheng A, Zhang X, Pan Y, Wang M, Huang J, Zhu D, Chen S, Liu M, Zhao X, Wu Y, Yang Q, Zhang S, Yu Y, Pan L, Tian B, Rehman MU, Chen X, Liu Y, Zhang L, Yin Z, Jing B, Jia R
Viruses 2020 Jan 14;12(1)
Viruses 2020 Jan 14;12(1)
RETRACTED: Endogenous production of C-C motif chemokine ligand 2 by nasopharyngeal carcinoma cells drives radioresistance-associated metastasis.
Guo SS, Liu R, Wen YF, Liu LT, Yuan L, Li YX, Li Y, Hao WW, Peng JY, Chen DN, Tang QN, Sun XS, Guo L, Mo HY, Qian CN, Zeng MS, Bei JX, Sun SY, Chen QY, Tang LQ, Mai HQ
Cancer letters 2020 Jan 1;468:27-40
Cancer letters 2020 Jan 1;468:27-40
Schizandrin B Mitigates Rifampicin-Induced Liver Injury by Inhibiting Endoplasmic Reticulum Stress.
Cheng L, Yang Z, Sun Z, Zhang W, Ren Y, Wang M, Han X, Fei L, Zhao Y, Pan H, Xie J, Nie S
Biological & pharmaceutical bulletin 2020 Jan 1;43(1):145-152
Biological & pharmaceutical bulletin 2020 Jan 1;43(1):145-152
Regulation of the firing activity by PKA-PKC-Src family kinases in cultured neurons of hypothalamic arcuate nucleus.
Sun XD, Wang A, Ma P, Gong S, Tao J, Yu XM, Jiang X
Journal of neuroscience research 2020 Feb;98(2):384-403
Journal of neuroscience research 2020 Feb;98(2):384-403
PITPNC1 fuels radioresistance of rectal cancer by inhibiting reactive oxygen species production.
Tan Y, Shao R, Li J, Huang H, Wang Y, Zhang M, Cao J, Zhang J, Bu J
Annals of translational medicine 2020 Feb;8(4):126
Annals of translational medicine 2020 Feb;8(4):126
Chronic toxicity of methamphetamine: Oxidative remodeling of pulmonary arteries.
Liang LY, Wang MM, Liu M, Zhao W, Wang X, Shi L, Zhu MJ, Zhao YL, Liu L, Maurya P, Wang Y
Toxicology in vitro : an international journal published in association with BIBRA 2020 Feb;62:104668
Toxicology in vitro : an international journal published in association with BIBRA 2020 Feb;62:104668
Beta-Amyloid Increases the Expression Levels of Tid1 Responsible for Neuronal Cell Death and Amyloid Beta Production.
Zhou C, Taslima F, Abdelhamid M, Kim SW, Akatsu H, Michikawa M, Jung CG
Molecular neurobiology 2020 Feb;57(2):1099-1114
Molecular neurobiology 2020 Feb;57(2):1099-1114
Association between different levels of lipid metabolism‑related enzymes and fatty acid synthase in Wilms' tumor.
Wang X, Du G, Wu Y, Zhang Y, Guo F, Liu W, Wu R
International journal of oncology 2020 Feb;56(2):568-580
International journal of oncology 2020 Feb;56(2):568-580
BDNF-TrkB pathway mediates antidepressant-like roles of H(2) S in diabetic rats via promoting hippocampal autophagy.
Liu HY, Wei HJ, Wu L, Liu SM, Tang YY, Zou W, Wang CY, Zhang P, Tang XQ
Clinical and experimental pharmacology & physiology 2020 Feb;47(2):302-312
Clinical and experimental pharmacology & physiology 2020 Feb;47(2):302-312
Transcription factor RUNX2 regulates epithelial‑mesenchymal transition and progression in renal cell carcinomas.
Liu B, Liu J, Yu H, Wang C, Kong C
Oncology reports 2020 Feb;43(2):609-616
Oncology reports 2020 Feb;43(2):609-616
Sirtuin 3 induces apoptosis and necroptosis by regulating mutant p53 expression in small‑cell lung cancer.
Tang X, Li Y, Liu L, Guo R, Zhang P, Zhang Y, Zhang Y, Zhao J, Su J, Sun L, Liu Y
Oncology reports 2020 Feb;43(2):591-600
Oncology reports 2020 Feb;43(2):591-600
Visfatin Exerts Immunotherapeutic Effects in Lipopolysaccharide-Induced Acute Lung Injury in Murine Model.
Luo Y, Pang XX, Ansari AR, Wu XT, Li HZ, Zhang ZW, Song H
Inflammation 2020 Feb;43(1):109-122
Inflammation 2020 Feb;43(1):109-122
Lactobacillus johnsonii L531 ameliorates enteritis via elimination of damaged mitochondria and suppression of SQSTM1-dependent mitophagy in a Salmonella infantis model of piglet diarrhea.
Xia B, Yu J, He T, Liu X, Su J, Wang M, Wang J, Zhu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2821-2839
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2821-2839
Berberine inhibits proliferation and migration of colorectal cancer cells by downregulation of GRP78.
Gong C, Hu X, Xu Y, Yang J, Zong L, Wang C, Zhu J, Li Z, Lu D
Anti-cancer drugs 2020 Feb;31(2):141-149
Anti-cancer drugs 2020 Feb;31(2):141-149
RhoB is regulated by hypoxia and modulates metastasis in breast cancer.
Ju JA, Godet I, DiGiacomo JW, Gilkes DM
Cancer reports (Hoboken, N.J.) 2020 Feb;3(1):e1164
Cancer reports (Hoboken, N.J.) 2020 Feb;3(1):e1164
Polychlorinated biphenyl quinone promotes macrophage polarization to CD163(+) cells through Nrf2 signaling pathway.
Liu J, Yang B, Wang Y, Wu Y, Fan B, Zhu S, Song E, Song Y
Environmental pollution (Barking, Essex : 1987) 2020 Feb;257:113587
Environmental pollution (Barking, Essex : 1987) 2020 Feb;257:113587
LncRNA HRCEG, regulated by HDAC1, inhibits cells proliferation and epithelial-mesenchymal-transition in gastric cancer.
Wu S, Wu E, Wang D, Niu Y, Yue H, Zhang D, Luo J, Chen R
Cancer genetics 2020 Feb;241:25-33
Cancer genetics 2020 Feb;241:25-33
Mitochondrial respiratory chain damage and mitochondrial fusion disorder are involved in liver dysfunction of fluoride-induced mice.
Wang HW, Liu J, Wei SS, Zhao WP, Zhu SQ, Zhou BH
Chemosphere 2020 Feb;241:125099
Chemosphere 2020 Feb;241:125099
Effects of Starvation on Antioxidant-Related Signaling Molecules, Oxidative Stress, and Autophagy in Juvenile Chinese Perch Skeletal Muscle.
Wu P, Wang A, Cheng J, Chen L, Pan Y, Li H, Zhang Q, Zhang J, Chu W, Zhang J
Marine biotechnology (New York, N.Y.) 2020 Feb;22(1):81-93
Marine biotechnology (New York, N.Y.) 2020 Feb;22(1):81-93
Involvement of neurotrophic signaling in doxorubicin-induced cardiotoxicity.
Liao D, Zhang C, Liu N, Cao L, Wang C, Feng Q, Yao D, Long M, Jiang P
Experimental and therapeutic medicine 2020 Feb;19(2):1129-1135
Experimental and therapeutic medicine 2020 Feb;19(2):1129-1135
1,3-Dicaffeoylquinic acid targeting 14-3-3 tau suppresses human breast cancer cell proliferation and metastasis through IL6/JAK2/PI3K pathway.
Zhou Y, Fu X, Guan Y, Gong M, He K, Huang B
Biochemical pharmacology 2020 Feb;172:113752
Biochemical pharmacology 2020 Feb;172:113752
Discovery of a first-in-class EZH2 selective degrader.
Ma A, Stratikopoulos E, Park KS, Wei J, Martin TC, Yang X, Schwarz M, Leshchenko V, Rialdi A, Dale B, Lagana A, Guccione E, Parekh S, Parsons R, Jin J
Nature chemical biology 2020 Feb;16(2):214-222
Nature chemical biology 2020 Feb;16(2):214-222
PDE9 inhibition promotes proliferation of neural stem cells via cGMP-PKG pathway following oxygen-glucose deprivation/reoxygenation injury in vitro.
Huan X, Oumei C, Hongmei Q, Junxia Y, Xiaojiao M, Qingsong J
Neurochemistry international 2020 Feb;133:104630
Neurochemistry international 2020 Feb;133:104630
Predictive Value of Pin1 in Cervical Low-Grade Squamous Intraepithelial Lesions and Inhibition of Pin1 Exerts Potent Anticancer Activity against Human Cervical Cancer.
Guo YT, Lu Y, Jia YY, Qu HN, Qi D, Wang XQ, Song PY, Jin XS, Xu WH, Dong Y, Liang YY, Quan CS
Aging and disease 2020 Feb;11(1):44-59
Aging and disease 2020 Feb;11(1):44-59
Ferrostatin-1 mitigates cognitive impairment of epileptic rats by inhibiting P38 MAPK activation.
Ye Q, Zeng C, Luo C, Wu Y
Epilepsy & behavior : E&B 2020 Feb;103(Pt A):106670
Epilepsy & behavior : E&B 2020 Feb;103(Pt A):106670
The Combination of Fasting, Acute Resistance Exercise, and Protein Ingestion Led to Different Responses of Autophagy Markers in Gastrocnemius and Liver Samples.
Pinto AP, Vieira TS, Marafon BB, Batitucci G, Cabrera EMB, da Rocha AL, Kohama EB, Rodrigues KCC, de Moura LP, Pauli JR, Cintra DE, Ropelle ER, de Freitas EC, da Silva ASR
Nutrients 2020 Feb 28;12(3)
Nutrients 2020 Feb 28;12(3)
MicroRNA-377-3p alleviates IL-1β-caused chondrocyte apoptosis and cartilage degradation in osteoarthritis in part by downregulating ITGA6.
Tu Y, Ma T, Wen T, Yang T, Xue L, Cai M, Wang F, Guan M, Xue H
Biochemical and biophysical research communications 2020 Feb 26;523(1):46-53
Biochemical and biophysical research communications 2020 Feb 26;523(1):46-53
RNA Binding Protein RNPC1 Suppresses the Stemness of Human Endometrial Cancer Cells via Stabilizing MST1/2 mRNA.
Wu X, Wang Y, Zhong W, Cheng H, Tian Z
Medical science monitor : international medical journal of experimental and clinical research 2020 Feb 23;26:e921389
Medical science monitor : international medical journal of experimental and clinical research 2020 Feb 23;26:e921389
Targeting UBE4A Revives Viperin Protein in Epithelium to Enhance Host Antiviral Defense.
Yuan Y, Miao Y, Qian L, Zhang Y, Liu C, Liu J, Zuo Y, Feng Q, Guo T, Zhang L, Chen X, Jin L, Huang F, Zhang H, Zhang W, Li W, Xu G, Zheng H
Molecular cell 2020 Feb 20;77(4):734-747.e7
Molecular cell 2020 Feb 20;77(4):734-747.e7
Polyphyllin VII attenuated RANKL-induced osteoclast differentiation via inhibiting of TRAF6/c-Src/PI3K pathway and ROS production.
Zhou L, Song H, Zhang Y, Ren Z, Li M, Fu Q
BMC musculoskeletal disorders 2020 Feb 19;21(1):112
BMC musculoskeletal disorders 2020 Feb 19;21(1):112
GRWD1 promotes cell proliferation and migration in non-small cell lung cancer by activating the Notch pathway.
Wang Q, Ren H, Xu Y, Jiang J, Wudu M, Liu Z, Su H, Jiang X, Zhang Y, Zhang B, Qiu X
Experimental cell research 2020 Feb 15;387(2):111806
Experimental cell research 2020 Feb 15;387(2):111806
Network Pharmacology-Based Prediction and Verification of Qingluo Tongbi Formula to Reduce Liver Toxicity of Tripterygium wilfordii via UGT2B7 in Endoplasmic Reticulum.
Li M, Wang J, Fu L, Lu Y, Xu J, Zhou L, Zhu H, Fang L, Feng Z, Xie T, Zhou X
Medical science monitor : international medical journal of experimental and clinical research 2020 Feb 15;26:e920376
Medical science monitor : international medical journal of experimental and clinical research 2020 Feb 15;26:e920376
PRL/microRNA-183/IRS1 Pathway Regulates Milk Fat Metabolism in Cow Mammary Epithelial Cells.
Jiao P, Yuan Y, Zhang M, Sun Y, Wei C, Xie X, Zhang Y, Wang S, Chen Z, Wang X
Genes 2020 Feb 13;11(2)
Genes 2020 Feb 13;11(2)
Sustained delivery of PlGF-2(123-144*)-fused BMP2-related peptide P28 from small intestinal submucosa/polylactic acid scaffold material for bone tissue regeneration.
Xiong Z, Cui W, Sun T, Teng Y, Qu Y, Yang L, Zhou J, Chen K, Yao S, Shao Z, Guo X
RSC advances 2020 Feb 13;10(12):7289-7300
RSC advances 2020 Feb 13;10(12):7289-7300
Doublecortin undergo nucleocytoplasmic transport via the RanGTPase signaling to promote glioma progression.
Ayanlaja AA, Ji G, Wang J, Gao Y, Cheng B, Kanwore K, Zhang L, Xiong Y, Kambey PA, Gao D
Cell communication and signaling : CCS 2020 Feb 12;18(1):24
Cell communication and signaling : CCS 2020 Feb 12;18(1):24
Curcumin Protects Human Trophoblast HTR8/SVneo Cells from H(2)O(2)-Induced Oxidative Stress by Activating Nrf2 Signaling Pathway.
Qi L, Jiang J, Zhang J, Zhang L, Wang T
Antioxidants (Basel, Switzerland) 2020 Feb 1;9(2)
Antioxidants (Basel, Switzerland) 2020 Feb 1;9(2)
Protective effect of resveratrol on obesity-related osteoarthritis via alleviating JAK2/STAT3 signaling pathway is independent of SOCS3.
Jiang M, He J, Gu H, Yang Y, Huang Y, Xu X, Liu L
Toxicology and applied pharmacology 2020 Feb 1;388:114871
Toxicology and applied pharmacology 2020 Feb 1;388:114871
PTP1B promotes macrophage activation by regulating the NF-κB pathway in alcoholic liver injury.
Yang L, Sun YY, Liu YR, Yin NN, Bu FT, Yu HX, Du XS, Li J, Huang C
Toxicology letters 2020 Feb 1;319:11-21
Toxicology letters 2020 Feb 1;319:11-21
Silencing of DsbA-L gene impairs the PPARγ agonist function of improving insulin resistance in a high-glucose cell model.
Zhou X, Li JQ, Wei LJ, He MZ, Jia J, Zhang JY, Wang SS, Feng L
Journal of Zhejiang University. Science. B 2020 Dec.;21(12):990-998
Journal of Zhejiang University. Science. B 2020 Dec.;21(12):990-998
SUMOylation of Pdia3 exacerbates proinsulin misfolding and ER stress in pancreatic beta cells.
Li N, Luo X, Yu Q, Yang P, Chen Z, Wang X, Jiang J, Xu J, Gong Q, Eizirik DL, Zhou Z, Zhao J, Xiong F, Zhang S, Wang CY
Journal of molecular medicine (Berlin, Germany) 2020 Dec;98(12):1795-1807
Journal of molecular medicine (Berlin, Germany) 2020 Dec;98(12):1795-1807
LXA4 protects against hypoxic-ischemic damage in neonatal rats by reducing the inflammatory response via the IκB/NF-κB pathway.
Zhu JJ, Yu BY, Fu CC, He MZ, Zhu JH, Chen BW, Zheng YH, Chen SQ, Fu XQ, Li PJ, Lin ZL
International immunopharmacology 2020 Dec;89(Pt B):107095
International immunopharmacology 2020 Dec;89(Pt B):107095
Annexin A3 upregulates the infiltrated neutrophil-lymphocyte ratio to remodel the immune microenvironment in hepatocellular carcinoma.
Zhu Q, Pan QZ, Zhong AL, Hu H, Zhao JJ, Tang Y, Hu WM, Li M, Weng DS, Chen MY, Ma G, Xia JC
International immunopharmacology 2020 Dec;89(Pt A):107139
International immunopharmacology 2020 Dec;89(Pt A):107139
Angiopoietin-like protein 4 promotes very-low-density lipoprotein assembly and secretion in bovine hepatocytes in vitro.
Kong Y, Zhao C, Huang Y, Liu Y, Liu S, Guo Y, Li M, Xu T, Zhao B, Wang J
IUBMB life 2020 Dec;72(12):2710-2721
IUBMB life 2020 Dec;72(12):2710-2721
Quercetin alleviates neonatal hypoxic-ischemic brain injury by inhibiting microglia-derived oxidative stress and TLR4-mediated inflammation.
Le K, Song Z, Deng J, Peng X, Zhang J, Wang L, Zhou L, Bi H, Liao Z, Feng Z
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2020 Dec;69(12):1201-1213
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2020 Dec;69(12):1201-1213
Knockdown of eukaryotic translation initiation factor 5A2 enhances the therapeutic efficiency of doxorubicin in hepatocellular carcinoma cells by triggering lethal autophagy.
Tang Y, Chen K, Luan X, Zhang J, Liu R, Zheng X, Xie S, Ke H, Zhang X, Chen W
International journal of oncology 2020 Dec;57(6):1368-1380
International journal of oncology 2020 Dec;57(6):1368-1380
Nobiletin Ameliorates NLRP3 Inflammasome-Mediated Inflammation Through Promoting Autophagy via the AMPK Pathway.
Wang H, Guo Y, Qiao Y, Zhang J, Jiang P
Molecular neurobiology 2020 Dec;57(12):5056-5068
Molecular neurobiology 2020 Dec;57(12):5056-5068
An antiviral drug-resistant mutant of hepatitis B virus with high replication capacity in association with a large in-frame deletion in the preS1 region of viral surface gene.
Wang T, Qin Y, Zhang J, Li X, Tong S, Zhao W, Zhang J
Virus genes 2020 Dec;56(6):677-686
Virus genes 2020 Dec;56(6):677-686
Intratunical injection of human urine-derived stem cells derived exosomes prevents fibrosis and improves erectile function in a rat model of Peyronie's disease.
Yang Q, Chen W, Han D, Zhang C, Xie Y, Sun X, Liu G, Deng C
Andrologia 2020 Dec;52(11):e13831
Andrologia 2020 Dec;52(11):e13831
MMP7 damages the integrity of the renal tubule epithelium by activating MMP2/9 during ischemia-reperfusion injury.
Hu Q, Lan J, Liang W, Chen Y, Chen B, Liu Z, Xiong Y, Zhong Z, Wang Y, Ye Q
Journal of molecular histology 2020 Dec;51(6):685-700
Journal of molecular histology 2020 Dec;51(6):685-700
Down-Regulated CUEDC2 Increases GDNF Expression by Stabilizing CREB Through Reducing Its Ubiquitination in Glioma.
Liu XF, Tang CX, Zhang L, Tong SY, Wang Y, Abdulrahman AA, Ji GQ, Gao Y, Gao DS, Zhang BL
Neurochemical research 2020 Dec;45(12):2915-2925
Neurochemical research 2020 Dec;45(12):2915-2925
Aberrant expression of miRNA-192-5p contributes to N,N-dimethylformamide-induced hepatic apoptosis.
Zhang Z, Zhu W, Liu Z, Liu Y, Chang C, Jiang H, Li R, Xiao Y, Chen W, Hu Q, Wang Q
Journal of applied toxicology : JAT 2020 Dec;40(12):1683-1693
Journal of applied toxicology : JAT 2020 Dec;40(12):1683-1693
Histone demethylase JHDM2A regulates H3K9 dimethylation in response to arsenic-induced DNA damage and repair in normal human liver cells.
Zhang AL, Tang SF, Yang Y, Li CZ, Ding XJ, Zhao H, Wang JH, Yang GH, Li J
Journal of applied toxicology : JAT 2020 Dec;40(12):1661-1672
Journal of applied toxicology : JAT 2020 Dec;40(12):1661-1672
Inhibition of ACSL4 attenuates ferroptotic damage after pulmonary ischemia-reperfusion.
Xu Y, Li X, Cheng Y, Yang M, Wang R
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16262-16275
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16262-16275
PFOS-induced placental cell growth inhibition is partially mediated by lncRNA H19 through interacting with miR-19a and miR-19b.
Li J, Quan XJ, Chen G, Hong JW, Wang Q, Xu LL, Wang BH, Yu ZH, Yu HM
Chemosphere 2020 Dec;261:127640
Chemosphere 2020 Dec;261:127640
Molecular identification, tissue distribution and in vitro functional analysis of growth hormone and its receptors in red-spotted grouper (Epinephelus akaara).
Yuan X, Lin Y, Qin J, Zhang Y, Yang G, Cai R, Liao Z, Sun C, Li W
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2020 Dec;250:110488
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2020 Dec;250:110488
Inhibition of CACNA1H can alleviate endoplasmic reticulum stress and reduce myocardial cell apoptosis caused by myocardial infarction.
Wang MX, Liu X, Li JM, Liu L, Lu W, Chen GC
European review for medical and pharmacological sciences 2020 Dec;24(24):12887-12895
European review for medical and pharmacological sciences 2020 Dec;24(24):12887-12895
FABP4 inhibitor attenuates inflammation and endoplasmic reticulum stress of islet in leptin receptor knockout rats.
Yao F, Jiang DD, Guo WH, Guo LS, Gao MM, Bai Y, Wang X, Zhang LS
European review for medical and pharmacological sciences 2020 Dec;24(24):12808-12820
European review for medical and pharmacological sciences 2020 Dec;24(24):12808-12820
Polarization of ADAM17-driven EGFR signalling in electric field-guided collective migration of epidermal sheets.
Jia N, Liu J, Zhu G, Liang Y, Wang Y, Wang W, Chen Y, Yang J, Zhang W, Zhang J
Journal of cellular and molecular medicine 2020 Dec;24(23):14073-14085
Journal of cellular and molecular medicine 2020 Dec;24(23):14073-14085
The proinflammatory cytokines IL-1β and TNF-α modulate corneal epithelial wound healing through p16(Ink4a) suppressing STAT3 activity.
Wang X, Zhang S, Dong M, Li Y, Zhou Q, Yang L
Journal of cellular physiology 2020 Dec;235(12):10081-10093
Journal of cellular physiology 2020 Dec;235(12):10081-10093
miR-448-3p alleviates diabetic vascular dysfunction by inhibiting endothelial-mesenchymal transition through DPP-4 dysregulation.
Guan GY, Wei N, Song T, Zhao C, Sun Y, Pan RX, Zhang LL, Xu YY, Dai YM, Han H
Journal of cellular physiology 2020 Dec;235(12):10024-10036
Journal of cellular physiology 2020 Dec;235(12):10024-10036
Inhibition of p38 MAPK regulates epileptic severity by decreasing expression levels of A1R and ENT1.
Zhou X, Chen Q, Huang H, Zhang J, Wang J, Chen Y, Peng Y, Zhang H, Zeng J, Feng Z, Xu Z
Molecular medicine reports 2020 Dec;22(6):5348-5357
Molecular medicine reports 2020 Dec;22(6):5348-5357
Effect of TFAM on ATP content in tachypacing primary cultured cardiomyocytes and atrial fibrillation patients.
Liu Y, Zhao Y, Tang R, Jiang X, Wang Y, Gu T
Molecular medicine reports 2020 Dec;22(6):5105-5112
Molecular medicine reports 2020 Dec;22(6):5105-5112
IGFBP‑rP1‑silencing promotes hypoxia‑induced angiogenic potential of choroidal endothelial cells via the RAF/MEK/ERK signaling pathway.
Zhu S, Wang H, Zhang Z, Ma M, Zheng Z, Xu X, Sun T
Molecular medicine reports 2020 Dec;22(6):4837-4847
Molecular medicine reports 2020 Dec;22(6):4837-4847
Pseudolaric acid B induces apoptosis in human rhabdomyosarcoma RD cells.
Liu C, Wang F, Wang B, Wu T, Wang Y, Huo W, Zhang S, Su Y, Liu J, Liu Y, Yu J
Oncology letters 2020 Dec;20(6):358
Oncology letters 2020 Dec;20(6):358
A Combination of BRD4 and HDAC3 Inhibitors Synergistically Suppresses Glioma Stem Cell Growth by Blocking GLI1/IL6/STAT3 Signaling Axis.
Wang Q, Jia S, Wang D, Chen X, Kalvakolanu DV, Zheng H, Wei X, Wen N, Liang H, Guo B, Zhang L
Molecular cancer therapeutics 2020 Dec;19(12):2542-2553
Molecular cancer therapeutics 2020 Dec;19(12):2542-2553
Resveratrol improves meat quality, muscular antioxidant capacity, lipid metabolism and fiber type composition of intrauterine growth retarded pigs.
Cheng K, Yu C, Li Z, Li S, Yan E, Song Z, Zhang H, Zhang L, Wang T
Meat science 2020 Dec;170:108237
Meat science 2020 Dec;170:108237
Polymethoxyflavones from citrus inhibited gastric cancer cell proliferation through inducing apoptosis by upregulating RARβ, both in vitro and in vivo.
Wang Y, Chen Y, Zhang H, Chen J, Cao J, Chen Q, Li X, Sun C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Dec;146:111811
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Dec;146:111811
Cannabinoid receptor subtype influence on neuritogenesis in human SH-SY5Y cells.
Lyons EL, Leone-Kabler S, Kovach AL, Thomas BF, Howlett AC
Molecular and cellular neurosciences 2020 Dec;109:103566
Molecular and cellular neurosciences 2020 Dec;109:103566
Andrographolide exerts anti-inflammatory effects in Mycobacterium tuberculosis-infected macrophages by regulating the Notch1/Akt/NF-κB axis.
He W, Sun J, Zhang Q, Li Y, Fu Y, Zheng Y, Jiang X
Journal of leukocyte biology 2020 Dec;108(6):1747-1764
Journal of leukocyte biology 2020 Dec;108(6):1747-1764
Structural and Functional Characterization of Host FHL1 Protein Interaction with Hypervariable Domain of Chikungunya Virus nsP3 Protein.
Lukash T, Agback T, Dominguez F, Shiliaev N, Meshram C, Frolova EI, Agback P, Frolov I
Journal of virology 2020 Dec 9;95(1)
Journal of virology 2020 Dec 9;95(1)
β-Elemene enhances radiosensitivity in non-small-cell lung cancer by inhibiting epithelial-mesenchymal transition and cancer stem cell traits via Prx-1/NF-kB/iNOS signaling pathway.
Zou K, Li Z, Zhang Y, Mu L, Chen M, Wang R, Deng W, Zou L, Liu J
Aging 2020 Dec 9;13(2):2575-2592
Aging 2020 Dec 9;13(2):2575-2592
Condensation of Rubisco into a proto-pyrenoid in higher plant chloroplasts.
Atkinson N, Mao Y, Chan KX, McCormick AJ
Nature communications 2020 Dec 9;11(1):6303
Nature communications 2020 Dec 9;11(1):6303
Exploration of the Effects of Substrate Stiffness on Biological Responses of Neural Cells and Their Mechanisms.
Zhang C, Tan Y, Feng J, Huang C, Liu B, Fan Z, Xu B, Lu T
ACS omega 2020 Dec 8;5(48):31115-31125
ACS omega 2020 Dec 8;5(48):31115-31125
circ_2858 Helps Blood-Brain Barrier Disruption by Increasing VEGFA via Sponging miR-93-5p during Escherichia coli Meningitis.
Yang R, Chen J, Xu B, Yang B, Fu J, Xiao S, Tan C, Chen H, Wang X
Molecular therapy. Nucleic acids 2020 Dec 4;22:708-721
Molecular therapy. Nucleic acids 2020 Dec 4;22:708-721
Metabotropic glutamate receptor 5 regulates synaptic plasticity in a chronic migraine rat model through the PKC/NR2B signal.
Niu Y, Zeng X, Zhao L, Zhou Y, Qin G, Zhang D, Fu Q, Zhou J, Chen L
The journal of headache and pain 2020 Dec 4;21(1):139
The journal of headache and pain 2020 Dec 4;21(1):139
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein inhibits type I and III interferon production by targeting RIG-I/MDA-5 signaling.
Zheng Y, Zhuang MW, Han L, Zhang J, Nan ML, Zhan P, Kang D, Liu X, Gao C, Wang PH
Signal transduction and targeted therapy 2020 Dec 28;5(1):299
Signal transduction and targeted therapy 2020 Dec 28;5(1):299
TRIM24 promotes stemness and invasiveness of glioblastoma cells via activating Sox2 expression.
Zhang LH, Yin YH, Chen HZ, Feng SY, Liu JL, Chen L, Fu WL, Sun GC, Yu XG, Xu DG
Neuro-oncology 2020 Dec 18;22(12):1797-1808
Neuro-oncology 2020 Dec 18;22(12):1797-1808
RIPK1 Distinctly Regulates Yersinia-Induced Inflammatory Cell Death, PANoptosis.
Malireddi RKS, Kesavardhana S, Karki R, Kancharana B, Burton AR, Kanneganti TD
ImmunoHorizons 2020 Dec 11;4(12):789-796
ImmunoHorizons 2020 Dec 11;4(12):789-796
Ubiquitination of RIPK1 regulates its activation mediated by TNFR1 and TLRs signaling in distinct manners.
Li X, Zhang M, Huang X, Liang W, Li G, Lu X, Li Y, Pan H, Shi L, Zhu H, Qian L, Shan B, Yuan J
Nature communications 2020 Dec 11;11(1):6364
Nature communications 2020 Dec 11;11(1):6364
Exploring the mechanism of cisplatin resistance by transcriptome sequencing and reversing the chemoresistance by autophagy inhibition in small cell lung cancer.
Ma K, Li S, Huo X, Guo M, Du X, Li C, Liu X, Lv J, Chen Z
Biochemical and biophysical research communications 2020 Dec 10;533(3):474-480
Biochemical and biophysical research communications 2020 Dec 10;533(3):474-480
Podocyte-derived extracellular vesicles mediate renal proximal tubule cells dedifferentiation via microRNA-221 in diabetic nephropathy.
Su H, Qiao J, Hu J, Li Y, Lin J, Yu Q, Zhen J, Ma Q, Wang Q, Lv Z, Wang R
Molecular and cellular endocrinology 2020 Dec 1;518:111034
Molecular and cellular endocrinology 2020 Dec 1;518:111034
PhospholipaseCγ1/calcium-dependent membranous localization of Gsdmd-N drives endothelial pyroptosis, contributing to lipopolysaccharide-induced fatal outcome.
Liu H, Tang D, Zhou X, Yang X, Chen AF
American journal of physiology. Heart and circulatory physiology 2020 Dec 1;319(6):H1482-H1495
American journal of physiology. Heart and circulatory physiology 2020 Dec 1;319(6):H1482-H1495
Effects of taraxasterol against ethanol and high-fat diet-induced liver injury by regulating TLR4/MyD88/NF-κB and Nrf2/HO-1 signaling pathways.
Li Z, Lian Y, Wei R, Jin L, Cao H, Zhao T, Ma X, Zhong M, Gao Y, Zhang K
Life sciences 2020 Dec 1;262:118546
Life sciences 2020 Dec 1;262:118546
NPY stimulates cholesterol synthesis acutely by activating the SREBP2-HMGCR pathway through the Y1 and Y5 receptors in murine hepatocytes.
Chen F, Zhou Y, Yang K, Shen M, Wang Y
Life sciences 2020 Dec 1;262:118478
Life sciences 2020 Dec 1;262:118478
Prostaglandin I2 mediates weak vasodilatation in human placental microvessels.
Feng X, Zhang Y, Zhang Y, Yang X, Man D, Lu L, Xu T, Liu Y, Yang C, Li H, Qi L, Su H, Zhou X, Xu Z
Biology of reproduction 2020 Dec 1;103(6):1229-1237
Biology of reproduction 2020 Dec 1;103(6):1229-1237
HOTAIR promotes paclitaxel resistance by regulating CHEK1 in ovarian cancer.
Jiang J, Wang S, Wang Z, Cai J, Han L, Xie L, Han Q, Wang W, Zhang Y, He X, Yang C
Cancer chemotherapy and pharmacology 2020 Aug;86(2):295-305
Cancer chemotherapy and pharmacology 2020 Aug;86(2):295-305
Ginsenoside Rk3 alleviated DSS-induced ulcerative colitis by protecting colon barrier and inhibiting NLRP3 inflammasome pathway.
Tian M, Ma P, Zhang Y, Mi Y, Fan D
International immunopharmacology 2020 Aug;85:106645
International immunopharmacology 2020 Aug;85:106645
Metformin inhibits extracellular matrix accumulation, inflammation and proliferation of mesangial cells in diabetic nephropathy by regulating H19/miR-143-3p/TGF-β1 axis.
Xu J, Xiang P, Liu L, Sun J, Ye S
The Journal of pharmacy and pharmacology 2020 Aug;72(8):1101-1109
The Journal of pharmacy and pharmacology 2020 Aug;72(8):1101-1109
GOLPH3 Regulates Exosome miRNA Secretion in Glioma Cells.
Hu P, Wang K, Zhou D, Wang L, Zhao M, Wang W, Zhang Y, Liu Y, Yu R, Zhou X
Journal of molecular neuroscience : MN 2020 Aug;70(8):1257-1266
Journal of molecular neuroscience : MN 2020 Aug;70(8):1257-1266
Metabolomic profiling reveals similar cytotoxic effects and protective functions of quercetin during deoxynivalenol- and 15-acetyl deoxynivalenol-induced cell apoptosis.
Yang YX, Yu S, Jia BX, Liu N, Wu A
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104838
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104838
All-Trans Retinoic Acid Exerts Neuroprotective Effects in Amyotrophic Lateral Sclerosis-Like Tg (SOD1*G93A)1Gur Mice.
Zhu Y, Liu Y, Yang F, Chen W, Jiang J, He P, Jiang S, Li M, Xu R
Molecular neurobiology 2020 Aug;57(8):3603-3615
Molecular neurobiology 2020 Aug;57(8):3603-3615
Exopolysaccharide from Cryptococcus heimaeyensis S20 induces autophagic cell death in non-small cell lung cancer cells via ROS/p38 and ROS/ERK signalling.
Hao Y, Huang Y, Chen J, Li J, Yuan Y, Wang M, Han L, Xin X, Wang H, Lin D, Peng F, Yu F, Zheng C, Shen C
Cell proliferation 2020 Aug;53(8):e12869
Cell proliferation 2020 Aug;53(8):e12869
Role of Zinc Sulphate in Immune Regulation in Artemisia annua Pollen-challenged P815 Mastocytoma Cells.
Yang FX, Hou L, Wen WL, Shen XL, Feng NY, Ma RX, Yin S
Immunological investigations 2020 Aug;49(6):622-631
Immunological investigations 2020 Aug;49(6):622-631
Exogenous spermine attenuates myocardial fibrosis in diabetic cardiomyopathy by inhibiting endoplasmic reticulum stress and the canonical Wnt signaling pathway.
Hu J, Lu X, Zhang X, Shao X, Wang Y, Chen J, Zhao B, Li S, Xu C, Wei C
Cell biology international 2020 Aug;44(8):1660-1670
Cell biology international 2020 Aug;44(8):1660-1670
Setosphapyrone C and D accelerate macrophages cholesterol efflux by promoting LXRα/ABCA1 pathway.
Li T, Yin J, Ji Y, Lin P, Li Y, Yang Z, Hu S, Wang J, Zhang B, Koshti S, Wang J, Ji C, Guo S
Archives of pharmacal research 2020 Aug;43(8):788-797
Archives of pharmacal research 2020 Aug;43(8):788-797
Thymidine phosphorylase promotes angiogenesis and tumour growth in intrahepatic cholangiocarcinoma.
Li S, Yang H, Li K, Fan G, Deng L, Xu C
Cell biochemistry and function 2020 Aug;38(6):743-752
Cell biochemistry and function 2020 Aug;38(6):743-752
Downregulation of miR-140-5p affects the pathogenesis of HSCR by targeting EGR2.
Du G, Wang X, Wu Y, Zhang Y, Liu W, Wu R
Pediatric surgery international 2020 Aug;36(8):883-890
Pediatric surgery international 2020 Aug;36(8):883-890
Inhibition of the facilitative sugar transporters (GLUTs) by tea extracts and catechins.
Ni D, Ai Z, Munoz-Sandoval D, Suresh R, Ellis PR, Yuqiong C, Sharp PA, Butterworth PJ, Yu Z, Corpe CP
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Aug;34(8):9995-10010
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Aug;34(8):9995-10010
Lnc00462717 regulates the permeability of the blood-brain tumor barrier through interaction with PTBP1 to inhibit the miR-186-5p/Occludin signaling pathway.
Zhang C, Zhang X, Wang J, Di F, Xue Y, Lin X, Zhang Y, Zhang H, Zhang Z, Gu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Aug;34(8):9941-9958
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Aug;34(8):9941-9958
USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylation.
Rusilowicz-Jones EV, Jardine J, Kallinos A, Pinto-Fernandez A, Guenther F, Giurrandino M, Barone FG, McCarron K, Burke CJ, Murad A, Martinez A, Marcassa E, Gersch M, Buckmelter AJ, Kayser-Bricker KJ, Lamoliatte F, Gajbhiye A, Davis S, Scott HC, Murphy E, England K, Mortiboys H, Komander D, Trost M, Kessler BM, Ioannidis S, Ahlijanian MK, Urbé S, Clague MJ
Life science alliance 2020 Aug;3(8)
Life science alliance 2020 Aug;3(8)
Pseudorabies virus infection inhibits stress granules formation via dephosphorylating eIF2α.
Xu S, Chen D, Chen D, Hu Q, Zhou L, Ge X, Han J, Guo X, Yang H
Veterinary microbiology 2020 Aug;247:108786
Veterinary microbiology 2020 Aug;247:108786
Protective effect of exogenous hydrogen sulfide on diaphragm muscle fibrosis in streptozotocin-induced diabetic rats.
Yang R, Jia Q, Li Y, Mehmood S
Experimental biology and medicine (Maywood, N.J.) 2020 Aug;245(14):1280-1289
Experimental biology and medicine (Maywood, N.J.) 2020 Aug;245(14):1280-1289
Cell cycle exit during bortezomib-induced osteogenic differentiation of mesenchymal stem cells was mediated by Xbp1s-upregulated p21(Cip1) and p27(Kip1).
Zhang D, Fan R, Lei L, Lei L, Wang Y, Lv N, Chen P, Williamson RA, Wang B, Hu J
Journal of cellular and molecular medicine 2020 Aug;24(16):9428-9438
Journal of cellular and molecular medicine 2020 Aug;24(16):9428-9438
Salvianic acid A alleviates chronic alcoholic liver disease by inhibiting HMGB1 translocation via down-regulating BRD4.
Lan Y, Yan R, Shan W, Chu J, Sun R, Wang R, Zhao Y, Wang Z, Zhang N, Yao J
Journal of cellular and molecular medicine 2020 Aug;24(15):8518-8531
Journal of cellular and molecular medicine 2020 Aug;24(15):8518-8531
Septin4 regulates endoplasmic reticulum stress and apoptosis in melatonin‑induced osteoblasts.
Tao L, Zhao S, Tao Z, Wen K, Zhou S, Da W, Zhu Y
Molecular medicine reports 2020 Aug;22(2):1179-1186
Molecular medicine reports 2020 Aug;22(2):1179-1186
Overexpression of negative regulator of ubiquitin-like proteins 1 (NUB1) inhibits proliferation and invasion of gastric cancer cells through upregulation of p27Kip1 and inhibition of epithelial-mesenchymal transition.
Zhang D, Wu P, Zhang Z, An W, Zhang C, Pan S, Tan Y, Xu H
Pathology, research and practice 2020 Aug;216(8):153002
Pathology, research and practice 2020 Aug;216(8):153002
Overexpression of B7-H4 promotes renal cell carcinoma progression by recruiting tumor-associated neutrophils via upregulation of CXCL8.
Li A, Zhang N, Zhao Z, Chen Y, Zhang L
Oncology letters 2020 Aug;20(2):1535-1544
Oncology letters 2020 Aug;20(2):1535-1544
Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated β-catenin pathway and EMT in colorectal cancer.
Liu D, Zhang H, Cui M, Chen C, Feng Y
Cell cycle (Georgetown, Tex.) 2020 Aug;19(15):1917-1927
Cell cycle (Georgetown, Tex.) 2020 Aug;19(15):1917-1927
Catalase is required for peroxisome maintenance during adipogenesis.
Nitta Y, Muraoka-Hirayama S, Sakurai K
Biochimica et biophysica acta. Molecular and cell biology of lipids 2020 Aug;1865(8):158726
Biochimica et biophysica acta. Molecular and cell biology of lipids 2020 Aug;1865(8):158726
Targeting G6PD reverses paclitaxel resistance in ovarian cancer by suppressing GSTP1.
Feng Q, Li X, Sun W, Sun M, Li Z, Sheng H, Xie F, Zhang S, Shan C
Biochemical pharmacology 2020 Aug;178:114092
Biochemical pharmacology 2020 Aug;178:114092
Localization of ZIP14 and ZIP8 in HIBCPP Cells.
Morgan SE, Schroten H, Ishikawa H, Zhao N
Brain sciences 2020 Aug 8;10(8)
Brain sciences 2020 Aug 8;10(8)
Reelin Promotes Cisplatin Resistance by Induction of Epithelial-Mesenchymal Transition via p38/GSK3β/Snail Signaling in Non-Small Cell Lung Cancer.
Li JM, Yang F, Li J, Yuan WQ, Wang H, Luo YQ
Medical science monitor : international medical journal of experimental and clinical research 2020 Aug 7;26:e925298
Medical science monitor : international medical journal of experimental and clinical research 2020 Aug 7;26:e925298
STIM1-mediated calcium influx controls antifungal immunity and the metabolic function of non-pathogenic Th17 cells.
Kahlfuss S, Kaufmann U, Concepcion AR, Noyer L, Raphael D, Vaeth M, Yang J, Pancholi P, Maus M, Muller J, Kozhaya L, Khodadadi-Jamayran A, Sun Z, Shaw P, Unutmaz D, Stathopulos PB, Feist C, Cameron SB, Turvey SE, Feske S
EMBO molecular medicine 2020 Aug 7;12(8):e11592
EMBO molecular medicine 2020 Aug 7;12(8):e11592
Selective Translation of Cell Fate Regulators Mediates Tolerance to Broad Oncogenic Stress.
Cai EY, Kufeld MN, Schuster S, Arora S, Larkin M, Germanos AA, Hsieh AC, Beronja S
Cell stem cell 2020 Aug 6;27(2):270-283.e7
Cell stem cell 2020 Aug 6;27(2):270-283.e7
Development of a Cationic Amphiphilic Helical Peptidomimetic (B18L) As A Novel Anti-Cancer Drug Lead.
Lyu Y, Kopcho S, Alvarez FA, Okeoma BC, Okeoma CM
Cancers 2020 Aug 28;12(9)
Cancers 2020 Aug 28;12(9)
Hippuric Acid Promotes Renal Fibrosis by Disrupting Redox Homeostasis via Facilitation of NRF2-KEAP1-CUL3 Interactions in Chronic Kidney Disease.
Sun B, Wang X, Liu X, Wang L, Ren F, Wang X, Leng X
Antioxidants (Basel, Switzerland) 2020 Aug 25;9(9)
Antioxidants (Basel, Switzerland) 2020 Aug 25;9(9)
Cotargeting of Mitochondrial Complex I and Bcl-2 Shows Antileukemic Activity against Acute Myeloid Leukemia Cells Reliant on Oxidative Phosphorylation.
Liu F, Kalpage HA, Wang D, Edwards H, Hüttemann M, Ma J, Su Y, Carter J, Li X, Polin L, Kushner J, Dzinic SH, White K, Wang G, Taub JW, Ge Y
Cancers 2020 Aug 24;12(9)
Cancers 2020 Aug 24;12(9)
α-Mangostin, a Dietary Xanthone, Exerts Protective Effects on Cisplatin-Induced Renal Injury via PI3K/Akt and JNK Signaling Pathways in HEK293 Cells.
Li Q, Yan XT, Zhao LC, Ren S, He YF, Liu WC, Wang Z, Li XD, Jiang S, Li W
ACS omega 2020 Aug 18;5(32):19960-19967
ACS omega 2020 Aug 18;5(32):19960-19967
Tetrandrine enhances glucocorticoid receptor translocation possibly via inhibition of P-glycoprotein in daunorubicin-resistant human T lymphoblastoid leukemia cells.
Xu W, Wang X, Chen S, Wu H, Tanaka S, Onda K, Sugiyama K, Yamada H, Hirano T
European journal of pharmacology 2020 Aug 15;881:173232
European journal of pharmacology 2020 Aug 15;881:173232
Bcl2 inhibitor ABT737 reverses the Warburg effect via the Sirt3-HIF1α axis to promote oxidative stress-induced apoptosis in ovarian cancer cells.
Dong D, Dong Y, Fu J, Lu S, Yuan C, Xia M, Sun L
Life sciences 2020 Aug 15;255:117846
Life sciences 2020 Aug 15;255:117846
Lactobacillus johnsonii L531 Ameliorates Escherichia coli-Induced Cell Damage via Inhibiting NLRP3 Inflammasome Activity and Promoting ATG5/ATG16L1-Mediated Autophagy in Porcine Mammary Epithelial Cells.
Zou YJ, Xu JJ, Wang X, Zhu YH, Wu Q, Wang JF
Veterinary sciences 2020 Aug 14;7(3)
Veterinary sciences 2020 Aug 14;7(3)
Plakoglobin is involved in cytoskeletal rearrangement of podocytes under the regulation of UCH-L1.
Fang Y, Li F, Qi C, Mao X, Xu Y, Zhao Z, Wu H, Zhang Z
Biochemical and biophysical research communications 2020 Aug 13;529(1):112-118
Biochemical and biophysical research communications 2020 Aug 13;529(1):112-118
Flavagline synthetic derivative induces senescence in glioblastoma cancer cells without being toxic to healthy astrocytes.
Harmouch E, Seitlinger J, Chaddad H, Ubeaud-Sequier G, Barths J, Saidu S, Désaubry L, Grandemange S, Massfelder T, Fuhrmann G, Fioretti F, Dontenwill M, Benkirane-Jessel N, Idoux-Gillet Y
Scientific reports 2020 Aug 13;10(1):13750
Scientific reports 2020 Aug 13;10(1):13750
Acetylation of Cytidine Residues Boosts HIV-1 Gene Expression by Increasing Viral RNA Stability.
Tsai K, Jaguva Vasudevan AA, Martinez Campos C, Emery A, Swanstrom R, Cullen BR
Cell host & microbe 2020 Aug 12;28(2):306-312.e6
Cell host & microbe 2020 Aug 12;28(2):306-312.e6
Cultivation of Hair Matrix Cells from Cashmere Goat Skins and Exemplified Applications.
Ma S, Wang L, Zong B, Wang Y, Wang X, Shi Y, Yang Y, Chen Y
Animals : an open access journal from MDPI 2020 Aug 12;10(8)
Animals : an open access journal from MDPI 2020 Aug 12;10(8)
The Small Molecule P7C3-A20 Exerts Neuroprotective Effects in a Hypoxic-ischemic Encephalopathy Model via Activation of PI3K/AKT/GSK3β Signaling.
Bai J, Zeng S, Zhu J, Fu C, He M, Zhu J, Chen S, Fu X, Li P, Lin Z
Neuroscience 2020 Aug 10;441:197-208
Neuroscience 2020 Aug 10;441:197-208
TMT-based proteomics analysis reveals the protective effects of Xuefu Zhuyu decoction in a rat model of traumatic brain injury.
Zhou D, Liu J, Hang Y, Li T, Li P, Guo S, Liu T, Xia Z, Wang Y
Journal of ethnopharmacology 2020 Aug 10;258:112826
Journal of ethnopharmacology 2020 Aug 10;258:112826
Lignans from Schisandra chinensis ameliorate alcohol and CCl(4)-induced long-term liver injury and reduce hepatocellular degeneration via blocking ETBR.
Xu JB, Gao GC, Yuan MJ, Huang X, Zhou HY, Zhang Y, Zheng YX, Wu Z, Feng JM, Wu JM
Journal of ethnopharmacology 2020 Aug 10;258:112813
Journal of ethnopharmacology 2020 Aug 10;258:112813
Role of ion channels in chronic intermittent hypoxia-induced atrial remodeling in rats.
Zhang K, Ma Z, Song C, Duan X, Yang Y, Li G
Life sciences 2020 Aug 1;254:117797
Life sciences 2020 Aug 1;254:117797
TLR4 knockout upregulates the expression of Mfn2 and PGC-1α in a high-fat diet and ischemia-reperfusion mice model of liver injury.
Zhang C, Jia Y, Liu B, Wang G, Zhang Y
Life sciences 2020 Aug 1;254:117762
Life sciences 2020 Aug 1;254:117762
Comparative analysis of two brine shrimps revealed differential expression pattern and functional characterization of CK2α under bacterial stimulation from different geographical distribution.
Wang Z, Hou Q, Wan K, Zhang R, Dong L, Zhang D, Yin H
Fish & shellfish immunology 2020 Apr;99:631-640
Fish & shellfish immunology 2020 Apr;99:631-640
Fangjihuangqi Decoction inhibits MDA-MB-231 cell invasion in vitro and decreases tumor growth and metastasis in triple-negative breast cancer xenografts tumor zebrafish model.
Guo Y, Fan Y, Pei X
Cancer medicine 2020 Apr;9(7):2564-2578
Cancer medicine 2020 Apr;9(7):2564-2578
Berberine combined with cyclosporine A alleviates acute graft-versus-host disease in murine models.
Wang M, Zhang J, Zhao H, Wan D, Jiang Z
International immunopharmacology 2020 Apr;81:106205
International immunopharmacology 2020 Apr;81:106205
Long non-coding RNA LOC100133669 promotes cell proliferation in oesophageal squamous cell carcinoma.
Guan Z, Wang Y, Wang Y, Liu X, Wang Y, Zhang W, Chi X, Dong Y, Liu X, Shao S, Zhan Q
Cell proliferation 2020 Apr;53(4):e12750
Cell proliferation 2020 Apr;53(4):e12750
Retinoid X receptor α (RXRα)-mediated erythroid-2-related factor-2 (NRF2) inactivation contributes to N,N-dimethylformamide (DMF)-induced oxidative stress in HL-7702 and HuH6 cells.
Jiang H, Li R, Zhang Z, Chang C, Liu Y, Liu Z, He Q, Wang Q
Journal of applied toxicology : JAT 2020 Apr;40(4):470-482
Journal of applied toxicology : JAT 2020 Apr;40(4):470-482
The Potential Role of PKA/CREB Signaling Pathway Concerned with Gastrodin Administration on Methamphetamine-Induced Conditioned Place Preference Rats and SH-SY5Y Cell Line.
Yang GM, Li L, Xue FL, Ma CL, Zeng XF, Zhao YN, Zhang DX, Yu Y, Yan QW, Zhou YQ, Hong SJ, Li LH
Neurotoxicity research 2020 Apr;37(4):926-935
Neurotoxicity research 2020 Apr;37(4):926-935
Virus analog decreases estradiol secretion in FSH-treated human ovarian granulosa cells.
Fang Y, Wang B, Lyu S, Zhang K, Cheng Q, Zhu Y
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2020 Apr;36(4):346-350
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2020 Apr;36(4):346-350
The deletion of mutant SOD1 via CRISPR/Cas9/sgRNA prolongs survival in an amyotrophic lateral sclerosis mouse model.
Duan W, Guo M, Yi L, Liu Y, Li Z, Ma Y, Zhang G, Liu Y, Bu H, Song X, Li C
Gene therapy 2020 Apr;27(3-4):157-169
Gene therapy 2020 Apr;27(3-4):157-169
MiR-129-5p protects against myocardial ischemia-reperfusion injury via targeting HMGB1.
Chen ZX, He D, Mo QW, Xie LP, Liang JR, Liu L, Fu WJ
European review for medical and pharmacological sciences 2020 Apr;24(8):4440-4450
European review for medical and pharmacological sciences 2020 Apr;24(8):4440-4450
Targeting STAT3 enhances NDV-induced immunogenic cell death in prostate cancer cells.
Wang X, Shao X, Gu L, Jiang K, Wang S, Chen J, Fang J, Guo X, Yuan M, Shi J, Ding C, Meng S, Xu Q
Journal of cellular and molecular medicine 2020 Apr;24(7):4286-4297
Journal of cellular and molecular medicine 2020 Apr;24(7):4286-4297
GLL398, an oral selective estrogen receptor degrader (SERD), blocks tumor growth in xenograft breast cancer models.
Guo S, Zhang C, Mottamal M, Hossain A, Liu J, Wang G
Breast cancer research and treatment 2020 Apr;180(2):359-368
Breast cancer research and treatment 2020 Apr;180(2):359-368
IL-29 promoted obesity-induced inflammation and insulin resistance.
Lin TY, Chiu CJ, Kuan CH, Chen FH, Shen YC, Wu CH, Hsu YH
Cellular & molecular immunology 2020 Apr;17(4):369-379
Cellular & molecular immunology 2020 Apr;17(4):369-379
NEK2 induces autophagy-mediated bortezomib resistance by stabilizing Beclin-1 in multiple myeloma.
Xia J, He Y, Meng B, Chen S, Zhang J, Wu X, Zhu Y, Shen Y, Feng X, Guan Y, Kuang C, Guo J, Lei Q, Wu Y, An G, Li G, Qiu L, Zhan F, Zhou W
Molecular oncology 2020 Apr;14(4):763-778
Molecular oncology 2020 Apr;14(4):763-778
A novel Sprouty4-ERK1/2-Wnt/β-catenin regulatory loop in marrow stromal progenitor cells controls osteogenic and adipogenic differentiation.
Tian L, Xiao H, Li M, Wu X, Xie Y, Zhou J, Zhang X, Wang B
Metabolism: clinical and experimental 2020 Apr;105:154189
Metabolism: clinical and experimental 2020 Apr;105:154189
Myxovirus resistance (Mx) gene and its differential expression regulated by three type I and two type II IFNs in mandarin fish, Siniperca chuatsi.
Li L, Chen SN, Laghari ZA, Huo HJ, Hou J, Huang L, Li N, Nie P
Developmental and comparative immunology 2020 Apr;105:103604
Developmental and comparative immunology 2020 Apr;105:103604
AKT but not MYC promotes reactive oxygen species-mediated cell death in oxidative culture.
Zheng D, Sussman JH, Jeon MP, Parrish ST, MacMullan MA, Delfarah A, Graham NA
Journal of cell science 2020 Apr 9;133(7)
Journal of cell science 2020 Apr 9;133(7)
p53-mediated control of aspartate-asparagine homeostasis dictates LKB1 activity and modulates cell survival.
Deng L, Yao P, Li L, Ji F, Zhao S, Xu C, Lan X, Jiang P
Nature communications 2020 Apr 9;11(1):1755
Nature communications 2020 Apr 9;11(1):1755
A Combination of Formic Acid and Monolaurin Attenuates Enterotoxigenic Escherichia coli Induced Intestinal Inflammation in Piglets by Inhibiting the NF-κB/MAPK Pathways with Modulation of Gut Microbiota.
Ren C, Wang Y, Lin X, Song H, Zhou Q, Xu W, Shi K, Chen J, Song J, Chen F, Zhang S, Guan W
Journal of agricultural and food chemistry 2020 Apr 8;68(14):4155-4165
Journal of agricultural and food chemistry 2020 Apr 8;68(14):4155-4165
Synergistic Neuroprotective Effect of Endogenously-Produced Hydroxytyrosol and Synaptic Vesicle Proteins on Pheochromocytoma Cell Line Against Salsolinol.
Manzoor R, Rasool A, Ahmed M, Kaleem U, Duru LN, Ma H, Deng Y
Molecules (Basel, Switzerland) 2020 Apr 8;25(7)
Molecules (Basel, Switzerland) 2020 Apr 8;25(7)
Interaction between PHB2 and Enterovirus A71 VP1 Induces Autophagy and Affects EV-A71 Infection.
Su W, Huang S, Zhu H, Zhang B, Wu X
Viruses 2020 Apr 8;12(4)
Viruses 2020 Apr 8;12(4)
Anti-neuroinflammatory effects of dimethylaminomylide (DMAMCL, i.e., ACT001) are associated with attenuating the NLRP3 inflammasome in MPTP-induced Parkinson disease in mice.
Liu Q, Guo X, Huang Z, He Q, Zhu D, Zhang S, Peng Z, Che Y, Feng X
Behavioural brain research 2020 Apr 6;383:112539
Behavioural brain research 2020 Apr 6;383:112539
MicroRNA-574-5p in gastric cancer cells promotes angiogenesis by targeting protein tyrosine phosphatase non-receptor type 3 (PTPN3).
Zhang S, Zhang R, Xu R, Shang J, He H, Yang Q
Gene 2020 Apr 5;733:144383
Gene 2020 Apr 5;733:144383
Effect of fluoride on osteocyte-driven osteoclastic differentiation.
Jiang N, Guo F, Xu W, Zhang Z, Jin H, Shi L, Zhang X, Gao J, Xu H
Toxicology 2020 Apr 30;436:152429
Toxicology 2020 Apr 30;436:152429
Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense.
Zheng M, Karki R, Vogel P, Kanneganti TD
Cell 2020 Apr 30;181(3):674-687.e13
Cell 2020 Apr 30;181(3):674-687.e13
Decreased ZNF750 promotes angiogenesis in a paracrine manner via activating DANCR/miR-4707-3p/FOXC2 axis in esophageal squamous cell carcinoma.
Bi Y, Guo S, Xu X, Kong P, Cui H, Yan T, Ma Y, Cheng Y, Chen Y, Liu X, Zhang L, Cheng C, Xu E, Qian Y, Yang J, Song B, Li H, Wang F, Hu X, Liu X, Niu X, Zhai Y, Liu J, Li Y, Cheng X, Cui Y
Cell death & disease 2020 Apr 27;11(4):296
Cell death & disease 2020 Apr 27;11(4):296
Cold atmospheric plasma induces GSDME-dependent pyroptotic signaling pathway via ROS generation in tumor cells.
Yang X, Chen G, Yu KN, Yang M, Peng S, Ma J, Qin F, Cao W, Cui S, Nie L, Han W
Cell death & disease 2020 Apr 27;11(4):295
Cell death & disease 2020 Apr 27;11(4):295
4β-Hydroxywithanolide E from Goldenberry (Whole Fruits of Physalis peruviana L.) as a Promising Agent against Chronic Obstructive Pulmonary Disease.
Yang WJ, Chen XM, Wang SQ, Hu HX, Cheng XP, Xu LT, Ren DM, Wang XN, Zhao BB, Lou HX, Shen T
Journal of natural products 2020 Apr 24;83(4):1217-1228
Journal of natural products 2020 Apr 24;83(4):1217-1228
HIF-1β Positively Regulates NF-κB Activity via Direct Control of TRAF6.
D'Ignazio L, Shakir D, Batie M, Muller HA, Rocha S
International journal of molecular sciences 2020 Apr 24;21(8)
International journal of molecular sciences 2020 Apr 24;21(8)
Maternal curcumin supplementation ameliorates placental function and fetal growth in mice with intrauterine growth retardation†.
Qi L, Jiang J, Zhang J, Zhang L, Wang T
Biology of reproduction 2020 Apr 24;102(5):1090-1101
Biology of reproduction 2020 Apr 24;102(5):1090-1101
Pathogenic Variants in CEP85L Cause Sporadic and Familial Posterior Predominant Lissencephaly.
Tsai MH, Muir AM, Wang WJ, Kang YN, Yang KC, Chao NH, Wu MF, Chang YC, Porter BE, Jansen LA, Sebire G, Deconinck N, Fan WL, Su SC, Chung WH, Almanza Fuerte EP, Mehaffey MG, University of Washington Center for Mendelian Genomics, Ng CC, Chan CK, Lim KS, Leventer RJ, Lockhart PJ, Riney K, Damiano JA, Hildebrand MS, Mirzaa GM, Dobyns WB, Berkovic SF, Scheffer IE, Tsai JW, Mefford HC
Neuron 2020 Apr 22;106(2):237-245.e8
Neuron 2020 Apr 22;106(2):237-245.e8
Soluble epoxide hydrolase inhibitor protects against blood-brain barrier dysfunction in a mouse model of type 2 diabetes via the AMPK/HO-1 pathway.
Wu J, Zhao Y, Fan Z, Chen Q, Chen J, Sun Y, Jiang X, Xiao Q
Biochemical and biophysical research communications 2020 Apr 2;524(2):354-359
Biochemical and biophysical research communications 2020 Apr 2;524(2):354-359
AcMNPV PKIP is required for hyperexpression of very late genes and involved in the hyperphosphorylation of the viral basic protein P6.9.
Lai Q, Xu L, Wang Y, Luo W, Zhu L, Yuan M, Wu W, Yang K
Virus research 2020 Apr 2;279:197889
Virus research 2020 Apr 2;279:197889
Circadian clock gene Clock is involved in the pathogenesis of preeclampsia through hypoxia.
Li Y, Li J, Hou Y, Huang L, Bian Y, Song G, Qiao C
Life sciences 2020 Apr 15;247:117441
Life sciences 2020 Apr 15;247:117441
STIM2 knockdown protects against ischemia/reperfusion injury through reducing mitochondrial calcium overload and preserving mitochondrial function.
Tu CC, Wan BY, Zeng Y
Life sciences 2020 Apr 15;247:116560
Life sciences 2020 Apr 15;247:116560
The SCF(β-TrCP) E3 Ubiquitin Ligase Regulates Immune Receptor Signaling by Targeting the Negative Regulatory Protein TIPE2.
Lou Y, Han M, Song Y, Zhong J, Zhang W, Chen YH, Wang H
Journal of immunology (Baltimore, Md. : 1950) 2020 Apr 15;204(8):2122-2132
Journal of immunology (Baltimore, Md. : 1950) 2020 Apr 15;204(8):2122-2132
Physicochemical characterization of polysaccharide from the leaf of Dendrobium officinale and effect on LPS induced damage in GES-1 cell.
Yang K, Lu T, Zhan L, Zhou C, Zhang N, Lei S, Wang Y, Yang J, Yan M, Lv G, Chen S
International journal of biological macromolecules 2020 Apr 15;149:320-330
International journal of biological macromolecules 2020 Apr 15;149:320-330
Trehalose attenuates renal ischemia-reperfusion injury by enhancing autophagy and inhibiting oxidative stress and inflammation.
Liu S, Yang Y, Gao H, Zhou N, Wang P, Zhang Y, Zhang A, Jia Z, Huang S
American journal of physiology. Renal physiology 2020 Apr 1;318(4):F994-F1005
American journal of physiology. Renal physiology 2020 Apr 1;318(4):F994-F1005
Localized injection of miRNA-21-enriched extracellular vesicles effectively restores cardiac function after myocardial infarction.
Song Y, Zhang C, Zhang J, Jiao Z, Dong N, Wang G, Wang Z, Wang L
Theranostics 2019;9(8):2346-2360
Theranostics 2019;9(8):2346-2360
HSF2 regulates aerobic glycolysis by suppression of FBP1 in hepatocellular carcinoma.
Yang LN, Ning ZY, Wang L, Yan X, Meng ZQ
American journal of cancer research 2019;9(8):1607-1621
American journal of cancer research 2019;9(8):1607-1621
Oncogenic MSH6-CXCR4-TGFB1 Feedback Loop: A Novel Therapeutic Target of Photothermal Therapy in Glioblastoma Multiforme.
Chen Y, Liu P, Sun P, Jiang J, Zhu Y, Dong T, Cui Y, Tian Y, An T, Zhang J, Li Z, Yang X
Theranostics 2019;9(5):1453-1473
Theranostics 2019;9(5):1453-1473
Targeting mitochondrial dynamics by regulating Mfn2 for therapeutic intervention in diabetic cardiomyopathy.
Hu L, Ding M, Tang D, Gao E, Li C, Wang K, Qi B, Qiu J, Zhao H, Chang P, Fu F, Li Y
Theranostics 2019;9(13):3687-3706
Theranostics 2019;9(13):3687-3706
Triptolide Induces Glioma Cell Autophagy and Apoptosis via Upregulating the ROS/JNK and Downregulating the Akt/mTOR Signaling Pathways.
Liu X, Zhao P, Wang X, Wang L, Zhu Y, Gao W
Frontiers in oncology 2019;9:387
Frontiers in oncology 2019;9:387
Identification of RE1-Silencing Transcription Factor as a Promoter of Metastasis in Pancreatic Cancer.
Jin H, Liu P, Kong L, Fei X, Gao Y, Wu T, Sun D, Tan X
Frontiers in oncology 2019;9:291
Frontiers in oncology 2019;9:291
Inhibition of oxidative stress by testosterone improves synaptic plasticity in senescence accelerated mice.
Wang L, Pei JH, Jia JX, Wang J, Song W, Fang X, Cai ZP, Huo DS, Wang H, Yang ZJ
Journal of toxicology and environmental health. Part A 2019;82(20):1061-1068
Journal of toxicology and environmental health. Part A 2019;82(20):1061-1068
Evidence for interaction of the NLRP3 inflammasome and Bruton's tyrosine kinase in tumor-associated macrophages: implications for myeloid cell production of interleukin-1beta.
Benner B, Scarberry L, Stiff A, Duggan MC, Good L, Lapurga G, Butchar JP, Tridandapani S, Carson WE
Oncoimmunology 2019;8(11):1659704
Oncoimmunology 2019;8(11):1659704
Bergenin Ameliorates MPTP-Induced Parkinson's Disease by Activating PI3K/Akt Signaling Pathway.
Ji Y, Wang D, Zhang B, Lu H
Journal of Alzheimer's disease : JAD 2019;72(3):823-833
Journal of Alzheimer's disease : JAD 2019;72(3):823-833
aFGF Promotes Neurite Growth by Regulating GSK3β-CRMP2 Signaling Pathway in Cortical Neurons Damaged by Amyloid-β.
Cao Q, Meng T, Man J, Peng D, Chen H, Xiang Q, Su Z, Zhang Q, Huang Y
Journal of Alzheimer's disease : JAD 2019;72(1):97-109
Journal of Alzheimer's disease : JAD 2019;72(1):97-109
Synergetic Inhibition of Human Colorectal Cancer Cells by Combining Polyyne-Enriched Fraction from Oplopanax elatus and Irinotecan.
Wang J, Shao L, Wang CZ, Zhou HH, Yuan CS, Huang WH
Nutrition and cancer 2019;71(3):472-482
Nutrition and cancer 2019;71(3):472-482
AAV9-Mediated Cdk5 Inhibitory Peptide Reduces Hyperphosphorylated Tau and Inflammation and Ameliorates Behavioral Changes Caused by Overexpression of p25 in the Brain.
Xu M, Huang Y, Song P, Huang Y, Huang W, Zhang HT, Hu Y
Journal of Alzheimer's disease : JAD 2019;70(2):573-585
Journal of Alzheimer's disease : JAD 2019;70(2):573-585
MiR-223-3p Alleviates Vascular Endothelial Injury by Targeting IL6ST in Kawasaki Disease.
Wang X, Ding YY, Chen Y, Xu QQ, Qian GH, Qian WG, Cao L, Zhou WP, Hou M, Lv HT
Frontiers in pediatrics 2019;7:288
Frontiers in pediatrics 2019;7:288
Loss of the Golgi Matrix Protein 130 Cause Aberrant IgA1 Glycosylation in IgA Nephropathy.
Wang C, Ye M, Zhao Q, Xia M, Liu D, He L, Chen G, Peng Y, Liu H
American journal of nephrology 2019;49(4):307-316
American journal of nephrology 2019;49(4):307-316
Chemo-Preventive Potential of Falcarindiol-Enriched Fraction from Oplopanax elatus on Colorectal Cancer Interfered by Human Gut Microbiota.
Wang J, Shao L, Rao T, Zhang W, Huang WH
The American journal of Chinese medicine 2019;47(6):1381-1404
The American journal of Chinese medicine 2019;47(6):1381-1404
Cinobufagin Promotes Cell Cycle Arrest and Apoptosis to Block Human Esophageal Squamous Cell Carcinoma Cells Growth via the p73 Signalling Pathway.
Deng X, Sheng J, Liu H, Wang N, Dai C, Wang Z, Zhang J, Zhao J, Dai E
Biological & pharmaceutical bulletin 2019;42(9):1500-1509
Biological & pharmaceutical bulletin 2019;42(9):1500-1509
Loss of Mitochondrial DNA by Gemcitabine Triggers Mitophagy and Cell Death.
Inamura A, Muraoka-Hirayama S, Sakurai K
Biological & pharmaceutical bulletin 2019;42(12):1977-1987
Biological & pharmaceutical bulletin 2019;42(12):1977-1987
RNA-seq analysis of PHD and VHL inhibitors reveals differences and similarities to the hypoxia response.
Frost J, Ciulli A, Rocha S
Wellcome open research 2019;4:17
Wellcome open research 2019;4:17
The Role of Nrf2 Signaling Pathway in Eucommia ulmoides Flavones Regulating Oxidative Stress in the Intestine of Piglets.
Xiao D, Yuan D, Tan B, Wang J, Liu Y, Tan B
Oxidative medicine and cellular longevity 2019;2019:9719618
Oxidative medicine and cellular longevity 2019;2019:9719618
Dexmedetomidine Attenuates Orthotopic Liver Transplantation-Induced Acute Gut Injury via α (2)-Adrenergic Receptor-Dependent Suppression of Oxidative Stress.
Lv P, Chen T, Liu P, Zheng L, Tian J, Tan F, Chen J, Deng Y, Li J, Cai J, Chi X
Oxidative medicine and cellular longevity 2019;2019:9426368
Oxidative medicine and cellular longevity 2019;2019:9426368
Paneth Cell Ablation Aggravates Pancreatic and Intestinal Injuries in a Rat Model of Acute Necrotizing Pancreatitis after Normal and High-Fat Diet.
Guo Y, Huang C, Liu L, Fu X, Lu Y, Zheng J, Mei Q, Huang Z, Fan J, Lu L, Zeng Y
Mediators of inflammation 2019;2019:8474523
Mediators of inflammation 2019;2019:8474523
Palmitic Acid Induces MicroRNA-221 Expression to Decrease Glucose Uptake in HepG2 Cells via the PI3K/AKT/GLUT4 Pathway.
Huang F, Chen J, Wang J, Zhu P, Lin W
BioMed research international 2019;2019:8171989
BioMed research international 2019;2019:8171989
Tetrandrine-Induced Autophagy in MDA-MB-231 Triple-Negative Breast Cancer Cell through the Inhibition of PI3K/AKT/mTOR Signaling.
Guo Y, Pei X
Evidence-based complementary and alternative medicine : eCAM 2019;2019:7517431
Evidence-based complementary and alternative medicine : eCAM 2019;2019:7517431
N-n-Butyl Haloperidol Iodide Ameliorates Oxidative Stress in Mitochondria Induced by Hypoxia/Reoxygenation through the Mitochondrial c-Jun N-Terminal Kinase/Sab/Src/Reactive Oxygen Species Pathway in H9c2 Cells.
Chu Q, Zhang Y, Zhong S, Gao F, Chen Y, Wang B, Zhang Z, Cai W, Li W, Zheng F, Shi G
Oxidative medicine and cellular longevity 2019;2019:7417561
Oxidative medicine and cellular longevity 2019;2019:7417561
Oral Administration of Lactobacillus delbrueckii during the Suckling Phase Improves Antioxidant Activities and Immune Responses after the Weaning Event in a Piglet Model.
Li Y, Hou S, Peng W, Lin Q, Chen F, Yang L, Li F, Huang X
Oxidative medicine and cellular longevity 2019;2019:6919803
Oxidative medicine and cellular longevity 2019;2019:6919803
Minocycline Protects against Rotenone-Induced Neurotoxicity Correlating with Upregulation of Nurr1 in a Parkinson's Disease Rat Model.
Sun C, Wang Y, Mo M, Song C, Wang X, Chen S, Liu Y
BioMed research international 2019;2019:6843265
BioMed research international 2019;2019:6843265
Phosphocreatine Improves Cardiac Dysfunction by Normalizing Mitochondrial Respiratory Function through JAK2/STAT3 Signaling Pathway In Vivo and In Vitro.
Qaed E, Wang J, Almoiliqy M, Song Y, Liu W, Chu P, Alademi S, Alademi M, Li H, Alshwmi M, Al-Azab M, Ahsan A, Mahdi S, Han G, Niu M, Ali A, Shopit A, Wang H, Li X, Qaid A, Ma X, Li T, Peng J, Ma J, Zhang J, Tang Z
Oxidative medicine and cellular longevity 2019;2019:6521218
Oxidative medicine and cellular longevity 2019;2019:6521218
CD133 Is Associated with Increased Melanoma Cell Survival after Multikinase Inhibition.
Simbulan-Rosenthal CM, Gaur A, Zhou H, AbdusSamad M, Qin Q, Dougherty R, Aljehane L, Kuo LW, Vakili S, Karna K, Clark H, McCarron E, Rosenthal DS
Journal of oncology 2019;2019:6486173
Journal of oncology 2019;2019:6486173
CTGF Attenuates Tendon-Derived Stem/Progenitor Cell Aging.
Rui YF, Chen MH, Li YJ, Xiao LF, Geng P, Wang P, Xu ZY, Zhang XP, Dai GC
Stem cells international 2019;2019:6257537
Stem cells international 2019;2019:6257537
Reactive Oxygen Species Are Involved in the Development of Gastric Cancer and Gastric Cancer-Related Depression through ABL1-Mediated Inflammation Signaling Pathway.
Huang T, Zhou F, Yuan X, Yang T, Liang X, Wang Y, Tu H, Chang J, Nan K, Wei Y
Oxidative medicine and cellular longevity 2019;2019:5813985
Oxidative medicine and cellular longevity 2019;2019:5813985
Purple Sweet Potato Color Attenuates Kidney Damage by Blocking VEGFR2/ROS/NLRP3 Signaling in High-Fat Diet-Treated Mice.
Zheng GH, Shan Q, Mu JJ, Wang YJ, Zhang ZF, Fan SH, Hu B, Li MQ, Xie J, Chen P, Wu DM, Lu J, Zheng YL
Oxidative medicine and cellular longevity 2019;2019:5189819
Oxidative medicine and cellular longevity 2019;2019:5189819
Nicorandil Attenuates LPS-Induced Acute Lung Injury by Pulmonary Endothelial Cell Protection via NF-κB and MAPK Pathways.
He M, Shi W, Yu M, Li X, Xu J, Zhu J, Jin L, Xie W, Kong H
Oxidative medicine and cellular longevity 2019;2019:4957646
Oxidative medicine and cellular longevity 2019;2019:4957646
Shuangyu Tiaozhi Granule Attenuates Hypercholesterolemia through the Reduction of Cholesterol Synthesis in Rat Fed a High Cholesterol Diet.
Shi J, Li R, Liu Y, Lu H, Yu L, Zhang F
BioMed research international 2019;2019:4805926
BioMed research international 2019;2019:4805926
Prevention of Huntington's Disease-Like Behavioral Deficits in R6/1 Mouse by Tolfenamic Acid Is Associated with Decreases in Mutant Huntingtin and Oxidative Stress.
Liu P, Li Y, Yang W, Liu D, Ji X, Chi T, Guo Z, Li L, Zou L
Oxidative medicine and cellular longevity 2019;2019:4032428
Oxidative medicine and cellular longevity 2019;2019:4032428
Bu Shen Zhu Yun Decoction Improves Endometrial Receptivity via VEGFR-2-Mediated Angiogenesis.
Li L, Jiang H, Wei X, Geng D, He M, Du H
Evidence-based complementary and alternative medicine : eCAM 2019;2019:3949824
Evidence-based complementary and alternative medicine : eCAM 2019;2019:3949824
Yiqihuoxue Formula Activates Autophagy and Offers Renoprotection in a Rat Model of Adenine-Induced Kidney Disease.
Xia CH, Han XT, Zhang X, Zhu ZB, Guo J, Cui HL, Jiang HX, Huang WJ, Chen GZ, Liu YN, Liu WJ
Evidence-based complementary and alternative medicine : eCAM 2019;2019:3423981
Evidence-based complementary and alternative medicine : eCAM 2019;2019:3423981
Curcumin and Curcumol Inhibit NF-κB and TGF-β (1)/Smads Signaling Pathways in CSE-Treated RAW246.7 Cells.
Li N, Liu TH, Yu JZ, Li CX, Liu Y, Wu YY, Yang ZS, Yuan JL
Evidence-based complementary and alternative medicine : eCAM 2019;2019:3035125
Evidence-based complementary and alternative medicine : eCAM 2019;2019:3035125
Astragalus Membranaceus Treatment Protects Raw264.7 Cells from Influenza Virus by Regulating G1 Phase and the TLR3-Mediated Signaling Pathway.
Liang Y, Zhang Q, Zhang L, Wang R, Xu X, Hu X
Evidence-based complementary and alternative medicine : eCAM 2019;2019:2971604
Evidence-based complementary and alternative medicine : eCAM 2019;2019:2971604
Salvianolic Acid A Protects the Kidney against Oxidative Stress by Activating the Akt/GSK-3β/Nrf2 Signaling Pathway and Inhibiting the NF-κB Signaling Pathway in 5/6 Nephrectomized Rats.
Zhang HF, Wang JH, Wang YL, Gao C, Gu YT, Huang J, Wang JH, Zhang Z
Oxidative medicine and cellular longevity 2019;2019:2853534
Oxidative medicine and cellular longevity 2019;2019:2853534
Stem Cells from Human Exfoliated Deciduous Teeth Ameliorate Diabetic Nephropathy In Vivo and In Vitro by Inhibiting Advanced Glycation End Product-Activated Epithelial-Mesenchymal Transition.
Rao N, Wang X, Xie J, Li J, Zhai Y, Li X, Fang T, Wang Y, Zhao Y, Ge L
Stem cells international 2019;2019:2751475
Stem cells international 2019;2019:2751475
Leukemia Inhibitory Factor Receptor Is Involved in Apoptosis in Rat Astrocytes Exposed to Oxygen-Glucose Deprivation.
Huo L, Fan Y, Wang H
BioMed research international 2019;2019:1613820
BioMed research international 2019;2019:1613820
Astragaloside IV Suppresses High Glucose-Induced NLRP3 Inflammasome Activation by Inhibiting TLR4/NF-κB and CaSR.
Leng B, Zhang Y, Liu X, Zhang Z, Liu Y, Wang H, Lu M
Mediators of inflammation 2019;2019:1082497
Mediators of inflammation 2019;2019:1082497
miR-100-3p inhibits cell proliferation and induces apoptosis in human gastric cancer through targeting to BMPR2.
Peng CW, Yue LX, Zhou YQ, Tang S, Kan C, Xia LM, Yang F, Wang SY
Cancer cell international 2019;19:354
Cancer cell international 2019;19:354
SSRP1 influences colorectal cancer cell growth and apoptosis via the AKT pathway.
Wang Q, Jia S, Jiao Y, Xu L, Wang D, Chen X, Hu X, Liang H, Wen N, Zhang S, Guo B, Zhang L
International journal of medical sciences 2019;16(12):1573-1582
International journal of medical sciences 2019;16(12):1573-1582
Fucoidan prevent murine autoimmune diabetes via suppression TLR4-signaling pathways, regulation DC/Treg induced immune tolerance and improving gut microecology.
Xue M, Liang H, Ji X, Liu Y, Ge Y, Hou L, Sun T
Nutrition & metabolism 2019;16:87
Nutrition & metabolism 2019;16:87
CXXC5 Mediates P. gingivalis-suppressed Cementoblast Functions Partially via MAPK Signaling Network.
Ma L, Wang X, Liu H, Jiang C, Liao H, Xu S, Guo Y, Cao Z
International journal of biological sciences 2019;15(8):1685-1695
International journal of biological sciences 2019;15(8):1685-1695
Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts.
Dias HB, de Oliveira JR, Donadio MVF, Kimura S
PloS one 2019;14(9):e0222202
PloS one 2019;14(9):e0222202
SPSB2 inhibits hepatitis C virus replication by targeting NS5A for ubiquitination and degradation.
Wang M, Wang Y, Liu Y, Wang H, Xin X, Li J, Hao Y, Han L, Yu F, Zheng C, Shen C
PloS one 2019;14(7):e0219989
PloS one 2019;14(7):e0219989
Resveratrol induced premature senescence and inhibited epithelial-mesenchymal transition of cancer cells via induction of tumor suppressor Rad9.
Chen KY, Chen CC, Chang YC, Chang MC
PloS one 2019;14(7):e0219317
PloS one 2019;14(7):e0219317
The Pseudogene PTTG3P Promotes Cell Migration and Invasion in Esophageal Squamous Cell Carcinoma.
Zhang Z, Shi Z
Open medicine (Warsaw, Poland) 2019;14:516-522
Open medicine (Warsaw, Poland) 2019;14:516-522
Synergism of cisplatin-oleanolic acid co-loaded calcium carbonate nanoparticles on hepatocellular carcinoma cells for enhanced apoptosis and reduced hepatotoxicity.
Khan MW, Zhao P, Khan A, Raza F, Raza SM, Sarfraz M, Chen Y, Li M, Yang T, Ma X, Xiang G
International journal of nanomedicine 2019;14:3753-3771
International journal of nanomedicine 2019;14:3753-3771
Treatment With Liraglutide Exerts Neuroprotection After Hypoxic-Ischemic Brain Injury in Neonatal Rats via the PI3K/AKT/GSK3β Pathway.
Zeng SS, Bai JJ, Jiang H, Zhu JJ, Fu CC, He MZ, Zhu JH, Chen SQ, Li PJ, Fu XQ, Lin ZL
Frontiers in cellular neuroscience 2019;13:585
Frontiers in cellular neuroscience 2019;13:585
Overexpression of CX3CR1 in Adipose-Derived Stem Cells Promotes Cell Migration and Functional Recovery After Experimental Intracerebral Hemorrhage.
Li G, Yu H, Liu N, Zhang P, Tang Y, Hu Y, Zhang Y, Pan C, Deng H, Wang J, Li Q, Tang Z
Frontiers in neuroscience 2019;13:462
Frontiers in neuroscience 2019;13:462
Arsenic sulfide induces miR-4665-3p to inhibit gastric cancer cell invasion and migration.
Zhang X, Tan Z, Kang T, Zhu C, Chen S
Drug design, development and therapy 2019;13:3037-3049
Drug design, development and therapy 2019;13:3037-3049
Hydrogen Sulfide Attenuates β2-Microglobulin-Induced Cognitive Dysfunction: Involving Recovery of Hippocampal Autophagic Flux.
Chen SM, Yi YL, Zeng D, Tang YY, Kang X, Zhang P, Zou W, Tang XQ
Frontiers in behavioral neuroscience 2019;13:244
Frontiers in behavioral neuroscience 2019;13:244
Necrostatin-1 Ameliorates Peripheral Nerve Injury-Induced Neuropathic Pain by Inhibiting the RIP1/RIP3 Pathway.
Liang YX, Wang NN, Zhang ZY, Juan ZD, Zhang C
Frontiers in cellular neuroscience 2019;13:211
Frontiers in cellular neuroscience 2019;13:211
The Neuroprotection of KIBRA in Promoting Neuron Survival and Against Amyloid β-Induced Apoptosis.
Song L, Tang S, Dong L, Han X, Cong L, Dong J, Han X, Zhang Q, Wang Y, Du Y
Frontiers in cellular neuroscience 2019;13:137
Frontiers in cellular neuroscience 2019;13:137
SUMOylation and deacetylation affect NF-κB p65 activity induced by high glucose in human lens epithelial cells.
Han X, Dong XX, Shi MY, Feng L, Wang XL, Zhang JS, Yan QC
International journal of ophthalmology 2019;12(9):1371-1379
International journal of ophthalmology 2019;12(9):1371-1379
Gatifloxacin inducing apoptosis of stromal fibroblasts through cross-talk between caspase-dependent extrinsic and intrinsic pathways.
Xu B, Sui YL, Fan TJ
International journal of ophthalmology 2019;12(10):1524-1530
International journal of ophthalmology 2019;12(10):1524-1530
Expression Of BMP7 In Ovarian Cancer And Biological Effect Of BMP7 Knockdown On Ovarian Cancer Cells.
Guan H, Li J, Sun R, Liu W, Feng M, Ma H, Li C
OncoTargets and therapy 2019;12:7897-7909
OncoTargets and therapy 2019;12:7897-7909
MicroRNA-765 sensitizes osteosarcoma cells to cisplatin via downregulating APE1 expression.
Liang W, Li C, Li M, Wang D, Zhong Z
OncoTargets and therapy 2019;12:7203-7214
OncoTargets and therapy 2019;12:7203-7214
LAPTM4B knockdown increases the radiosensitivity of EGFR-overexpressing radioresistant nasopharyngeal cancer cells by inhibiting autophagy.
Chu C, Niu X, Ou X, Hu C
OncoTargets and therapy 2019;12:5661-5677
OncoTargets and therapy 2019;12:5661-5677
β-elemene inhibits radiation and hypoxia-induced macrophages infiltration via Prx-1/NF-κB/HIF-1α signaling pathway.
Yu X, Li Z, Zhang Y, Xu M, Che Y, Tian X, Wang R, Zou K, Zou L
OncoTargets and therapy 2019;12:4203-4211
OncoTargets and therapy 2019;12:4203-4211
Exosomal Tenascin-c induces proliferation and invasion of pancreatic cancer cells by WNT signaling.
Qian S, Tan X, Liu X, Liu P, Wu Y
OncoTargets and therapy 2019;12:3197-3205
OncoTargets and therapy 2019;12:3197-3205
Multiple Functions of KBP in Neural Development Underlie Brain Anomalies in Goldberg-Shprintzen Syndrome.
Chang HY, Cheng HY, Tsao AN, Liu C, Tsai JW
Frontiers in molecular neuroscience 2019;12:265
Frontiers in molecular neuroscience 2019;12:265
Dichloroacetic acid upregulates apoptosis of ovarian cancer cells by regulating mitochondrial function.
Zhou L, Liu L, Chai W, Zhao T, Jin X, Guo X, Han L, Yuan C
OncoTargets and therapy 2019;12:1729-1739
OncoTargets and therapy 2019;12:1729-1739
miR-492 Promotes Cancer Progression by Targeting GJB4 and Is a Novel Biomarker for Bladder Cancer.
Wang K, Lü H, Qu H, Xie Q, Sun T, Gan O, Hu B
OncoTargets and therapy 2019;12:11453-11464
OncoTargets and therapy 2019;12:11453-11464
miR-509-5p Downregulation Is Associated With Male Infertility And Acts As A Suppressor In Testicular Germ Cell Tumor Cells Through Targeting MDM2.
Sun J, Niu L, Gao S, Yi X, Chen J
OncoTargets and therapy 2019;12:10515-10522
OncoTargets and therapy 2019;12:10515-10522
Escin protects against acetaminophen-induced liver injury in mice via attenuating inflammatory response and inhibiting ERK signaling pathway.
Lee HC, Yu HP, Liao CC, Chou AH, Liu FC
American journal of translational research 2019;11(8):5170-5182
American journal of translational research 2019;11(8):5170-5182
MiR-302a-5p suppresses cell proliferation and invasion in non-small cell lung carcinoma by targeting ITGA6.
Chen W, Zhuang X, Qi R, Qiao T
American journal of translational research 2019;11(7):4348-4357
American journal of translational research 2019;11(7):4348-4357
VASN promotes YAP/TAZ and EMT pathway in thyroid carcinogenesis in vitro.
Bhandari A, Guan Y, Xia E, Huang Q, Chen Y
American journal of translational research 2019;11(6):3589-3599
American journal of translational research 2019;11(6):3589-3599
Overexpression of CBX2 in breast cancer promotes tumor progression through the PI3K/AKT signaling pathway.
Zheng S, Lv P, Su J, Miao K, Xu H, Li M
American journal of translational research 2019;11(3):1668-1682
American journal of translational research 2019;11(3):1668-1682
BPTF cooperates with p50 NF-κB to promote COX-2 expression and tumor cell growth in lung cancer.
Dai M, Hu S, Liu CF, Jiang L, Yu W, Li ZL, Guo W, Tang R, Dong CY, Wu TH, Deng WG
American journal of translational research 2019;11(12):7398-7409
American journal of translational research 2019;11(12):7398-7409
Clinical roles of miR-136-5p and its target metadherin in thyroid carcinoma.
Gao RZ, Que Q, Lin P, Pang YY, Wu HY, Li XJ, Chen G, He Y, Yang H
American journal of translational research 2019;11(11):6754-6774
American journal of translational research 2019;11(11):6754-6774
Downregulation of angiopoietin-like protein 2 inhibits cementoblast differentiation partially by activating the ERK1/2 signaling pathway.
Jiang C, Liu H, Sun H, Wang X, Liao H, Ma L, Cao Z
American journal of translational research 2019;11(1):314-326
American journal of translational research 2019;11(1):314-326
ADAR1 may be involved in the proliferation of acute myeloid leukemia cells via regulation of the Wnt pathway.
Xiao H, Cheng Q, Wu X, Tang Y, Liu J, Li X
Cancer management and research 2019;11:8547-8555
Cancer management and research 2019;11:8547-8555
Overexpressed PKMYT1 promotes tumor progression and associates with poor survival in esophageal squamous cell carcinoma.
Zhang Q, Zhao X, Zhang C, Wang W, Li F, Liu D, Wu K, Zhu D, Liu S, Shen C, Yuan X, Zhang K, Yang Y, Zhang Y, Zhao S
Cancer management and research 2019;11:7813-7824
Cancer management and research 2019;11:7813-7824
HIF1α/miR-520a-3p/AKT1/mTOR Feedback Promotes The Proliferation And Glycolysis Of Gastric Cancer Cells.
Pan C, Liu Q, Wu X
Cancer management and research 2019;11:10145-10156
Cancer management and research 2019;11:10145-10156
STIP1 Regulates Proliferation and Migration of Lung Adenocarcinoma Through JAK2/STAT3 Signaling Pathway.
Guo X, Yan Z, Zhang G, Wang X, Pan Y, Huang M
Cancer management and research 2019;11:10061-10072
Cancer management and research 2019;11:10061-10072
Inhibition of RNA-Binding Protein Musashi-1 Suppresses Malignant Properties and Reverses Paclitaxel Resistance in Ovarian Carcinoma.
Chen H, Liu J, Wang H, Cheng Q, Zhou C, Chen X, Ye F
Journal of Cancer 2019;10(6):1580-1592
Journal of Cancer 2019;10(6):1580-1592
CLEC4M is associated with poor prognosis and promotes cisplatin resistance in NSCLC patients.
Tan LM, Li X, Qiu CF, Zhu T, Hu CP, Yin JY, Zhang W, Zhou HH, Liu ZQ
Journal of Cancer 2019;10(25):6374-6383
Journal of Cancer 2019;10(25):6374-6383
Methylation of SLFN11 promotes gastric cancer growth and increases gastric cancer cell resistance to cisplatin.
Peng Y, Wang L, Wu L, Zhang L, Nie G, Guo M
Journal of Cancer 2019;10(24):6124-6134
Journal of Cancer 2019;10(24):6124-6134
EP300 as an oncogene correlates with poor prognosis in esophageal squamous carcinoma.
Bi Y, Kong P, Zhang L, Cui H, Xu X, Chang F, Yan T, Li J, Cheng C, Song B, Niu X, Liu X, Liu X, Xu E, Hu X, Qian Y, Wang F, Li H, Ma Y, Yang J, Liu Y, Zhai Y, Wang Y, Zhang Y, Liu H, Liu J, Wang J, Cui Y, Cheng X
Journal of Cancer 2019;10(22):5413-5426
Journal of Cancer 2019;10(22):5413-5426
8-bromo-7-methoxychrysin targets NF-κB and FoxM1 to inhibit lung cancer stem cells induced by pro-inflammatory factors.
Yuan Q, Wen M, Xu C, Chen A, Qiu YB, Cao JG, Zhang JS, Song ZW
Journal of Cancer 2019;10(21):5244-5255
Journal of Cancer 2019;10(21):5244-5255
An NF90/long noncoding RNA-LET/miR-548k feedback amplification loop controls esophageal squamous cell carcinoma progression.
Lin J, Chen Z, Wu S, Huang W, Chen F, Huang Z
Journal of Cancer 2019;10(21):5139-5152
Journal of Cancer 2019;10(21):5139-5152
Verteporfin suppresses the proliferation, epithelial-mesenchymal transition and stemness of head and neck squamous carcinoma cells via inhibiting YAP1.
Liu K, Du S, Gao P, Zheng J
Journal of Cancer 2019;10(18):4196-4207
Journal of Cancer 2019;10(18):4196-4207
ITRAQ-Based Proteomics Analysis Reveals the Effect of Neoliensinine on KCl-Induced Vascular Smooth Muscle Contraction by Inhibiting Regulatory Light Chain Phosphorylation.
Yang GM, Yan K, Wang P, Zhang JL, Pan ZH, Pan Y
Frontiers in pharmacology 2019;10:979
Frontiers in pharmacology 2019;10:979
Discovery of N-(2-Aminophenyl)-4-(bis(2-chloroethyl)amino)Benzamide as a Potent Histone Deacetylase Inhibitor.
Zhang L, Li X, Chen Y, Wan M, Jiang Q, Zhang L, Chou CJ, Song W, Zhang L
Frontiers in pharmacology 2019;10:957
Frontiers in pharmacology 2019;10:957
A Novel Regulatory Circuit "C/EBPα/miR-20a-5p/TOB2" Regulates Adipogenesis and Lipogenesis.
Zhou J, Yang J, Wang X, Li M, Li F, Zhu E, Li X, Li X, Wang B
Frontiers in endocrinology 2019;10:894
Frontiers in endocrinology 2019;10:894
Effects of Exercise Training on the Autophagy-Related Muscular Proteins Expression in Ovariectomized Rats.
Zhong W, Shi X, Yuan H, Bu H, Wu L, Wang R
Frontiers in physiology 2019;10:735
Frontiers in physiology 2019;10:735
Irbesartan Ameliorates Lipid Deposition by Enhancing Autophagy via PKC/AMPK/ULK1 Axis in Free Fatty Acid Induced Hepatocytes.
He J, Ding J, Lai Q, Wang X, Li A, Liu S
Frontiers in physiology 2019;10:681
Frontiers in physiology 2019;10:681
Fish Autophagy Protein 5 Exerts Negative Regulation on Antiviral Immune Response Against Iridovirus and Nodavirus.
Li C, Liu J, Zhang X, Wei S, Huang X, Huang Y, Wei J, Qin Q
Frontiers in immunology 2019;10:517
Frontiers in immunology 2019;10:517
A Novel Postbiotic From Lactobacillus rhamnosus GG With a Beneficial Effect on Intestinal Barrier Function.
Gao J, Li Y, Wan Y, Hu T, Liu L, Yang S, Gong Z, Zeng Q, Wei Y, Yang W, Zeng Z, He X, Huang SH, Cao H
Frontiers in microbiology 2019;10:477
Frontiers in microbiology 2019;10:477
An improved Tet-on system in microRNA overexpression and CRISPR/Cas9-mediated gene editing.
Kang K, Huang L, Li Q, Liao X, Dang Q, Yang Y, Luo J, Zeng Y, Li L, Gou D
Journal of animal science and biotechnology 2019;10:43
Journal of animal science and biotechnology 2019;10:43
Identification of a Novel Bcl-2 Inhibitor by Ligand-Based Screening and Investigation of Its Anti-cancer Effect on Human Breast Cancer Cells.
Wen M, Deng ZK, Jiang SL, Guan YD, Wu HZ, Wang XL, Xiao SS, Zhang Y, Yang JM, Cao DS, Cheng Y
Frontiers in pharmacology 2019;10:391
Frontiers in pharmacology 2019;10:391
Prepartum body conditions affect insulin signaling pathways in postpartum adipose tissues in transition dairy cows.
Zhang F, Li D, Wu Q, Sun J, Guan W, Hou Y, Zhu Y, Wang J
Journal of animal science and biotechnology 2019;10:38
Journal of animal science and biotechnology 2019;10:38
Da-Bu-Yin-Wan and Qian-Zheng-San Ameliorate Mitochondrial Dynamics in the Parkinson's Disease Cell Model Induced by MPP().
Gai C, Feng WD, Qiang TY, Ma HJ, Chai Y, Zhang SJ, Guo ZY, Hu JH, Sun HM
Frontiers in pharmacology 2019;10:372
Frontiers in pharmacology 2019;10:372
The Involvement of Renin-Angiotensin System in Lipopolysaccharide-Induced Behavioral Changes, Neuroinflammation, and Disturbed Insulin Signaling.
Gong X, Hu H, Qiao Y, Xu P, Yang M, Dang R, Han W, Guo Y, Chen D, Jiang P
Frontiers in pharmacology 2019;10:318
Frontiers in pharmacology 2019;10:318
Epstein-Barr Virus Nuclear Antigen 1 Recruits Cyclophilin A to Facilitate the Replication of Viral DNA Genome.
Xin S, Du S, Liu L, Xie Y, Zuo L, Yang J, Hu J, Yue W, Zhang J, Cao P, Zhu F, Lu J
Frontiers in microbiology 2019;10:2879
Frontiers in microbiology 2019;10:2879
Dengue Virus Infection Activates Interleukin-1β to Induce Tissue Injury and Vascular Leakage.
Pan P, Zhang Q, Liu W, Wang W, Yu Z, Lao Z, Zhang W, Shen M, Wan P, Xiao F, Shereen MA, Zhang W, Tan Q, Liu Y, Liu X, Wu K, Liu Y, Li G, Wu J
Frontiers in microbiology 2019;10:2637
Frontiers in microbiology 2019;10:2637
Hypertensive Rats Treated Chronically With N(ω)-Nitro-L-Arginine Methyl Ester (L-NAME) Induced Disorder of Hepatic Fatty Acid Metabolism and Intestinal Pathophysiology.
Li B, He X, Lei SS, Zhou FC, Zhang NY, Chen YH, Wang YZ, Su J, Yu JJ, Li LZ, Zheng X, Luo R, Kołodyńska D, Xiong S, Lv GY, Chen SH
Frontiers in pharmacology 2019;10:1677
Frontiers in pharmacology 2019;10:1677
Cathelicidin-WA Facilitated Intestinal Fatty Acid Absorption Through Enhancing PPAR-γ Dependent Barrier Function.
Zong X, Cao X, Wang H, Xiao X, Wang Y, Lu Z
Frontiers in immunology 2019;10:1674
Frontiers in immunology 2019;10:1674
The Capsid Protein VP1 of Coxsackievirus B Induces Cell Cycle Arrest by Up-Regulating Heat Shock Protein 70.
Wang Y, Zhao S, Chen Y, Wang T, Dong C, Wo X, Zhang J, Dong Y, Xu W, Feng X, Qu C, Wang Y, Zhong Z, Zhao W
Frontiers in microbiology 2019;10:1633
Frontiers in microbiology 2019;10:1633
LncRNA LUCRC Regulates Colorectal Cancer Cell Growth and Tumorigenesis by Targeting Endoplasmic Reticulum Stress Response.
Tang GH, Chen X, Ding JC, Du J, Lin XT, Xia L, Lian JB, Ye F, He XS, Liu W
Frontiers in genetics 2019;10:1409
Frontiers in genetics 2019;10:1409
Ghrelin Attenuates Neuroinflammation and Demyelination in Experimental Autoimmune Encephalomyelitis Involving NLRP3 Inflammasome Signaling Pathway and Pyroptosis.
Liu F, Li Z, He X, Yu H, Feng J
Frontiers in pharmacology 2019;10:1320
Frontiers in pharmacology 2019;10:1320
An Improved Enzyme-Linked Focus Formation Assay Revealed Baloxavir Acid as a Potential Antiviral Therapeutic Against Hantavirus Infection.
Ye C, Wang D, Liu H, Ma H, Dong Y, Yao M, Wang Y, Zhang H, Zhang L, Cheng L, Xu Z, Lei Y, Zhang F, Ye W
Frontiers in pharmacology 2019;10:1203
Frontiers in pharmacology 2019;10:1203
LPS Induces Preeclampsia-Like Phenotype in Rats and HTR8/SVneo Cells Dysfunction Through TLR4/p38 MAPK Pathway.
Fan M, Li X, Gao X, Dong L, Xin G, Chen L, Qiu J, Xu Y
Frontiers in physiology 2019;10:1030
Frontiers in physiology 2019;10:1030
Sorghum Phenolics Inhibits Inflammasomes in Lipopolysaccharide (LPS)-Primed and Adenosine Triphosphate (ATP)-Activated Macrophages.
Dia VP, Bradwell J, Pangloli P
Plant foods for human nutrition (Dordrecht, Netherlands) 2019 Sep;74(3):307-315
Plant foods for human nutrition (Dordrecht, Netherlands) 2019 Sep;74(3):307-315
Functional evidence for a de novo mutation in WDR45 leading to BPAN in a Chinese girl.
Xiong Q, Li W, Li P, Zhao Z, Wu C, Xiao H
Molecular genetics & genomic medicine 2019 Sep;7(9):e858
Molecular genetics & genomic medicine 2019 Sep;7(9):e858
Aerobic Exercise Improves Synaptic-Related Proteins of Diabetic Rats by Inhibiting FOXO1/NF-κB/NLRP3 Inflammatory Signaling Pathway and Ameliorating PI3K/Akt Insulin Signaling Pathway.
Wang Q, Hu J, Liu Y, Li J, Liu B, Li M, Lou S
Journal of molecular neuroscience : MN 2019 Sep;69(1):28-38
Journal of molecular neuroscience : MN 2019 Sep;69(1):28-38
Comparison of the Effects of Green and Black Tea Extracts on Na(+) /K(+) -ATPase Activity in Intestine of Type 1 and Type 2 Diabetic Mice.
Qu F, Liu S, He C, Zhou J, Zhang S, Ai Z, Chen Y, Yu Z, Ni D
Molecular nutrition & food research 2019 Sep;63(17):e1801039
Molecular nutrition & food research 2019 Sep;63(17):e1801039
Mechanosensitive ion channel Piezo1 promotes prostate cancer development through the activation of the Akt/mTOR pathway and acceleration of cell cycle.
Han Y, Liu C, Zhang D, Men H, Huo L, Geng Q, Wang S, Gao Y, Zhang W, Zhang Y, Jia Z
International journal of oncology 2019 Sep;55(3):629-644
International journal of oncology 2019 Sep;55(3):629-644
MicroRNA-191 promotes hepatocellular carcinoma cell proliferation by has_circ_0000204/miR-191/KLF6 axis.
Tian F, Yu C, Wu M, Wu X, Wan L, Zhu X
Cell proliferation 2019 Sep;52(5):e12635
Cell proliferation 2019 Sep;52(5):e12635
Cardiac troponin I autoantibody induces myocardial dysfunction by PTEN signaling activation.
Wu Y, Qin YH, Liu Y, Zhu L, Zhao XX, Liu YY, Luo SW, Tang GS, Shen Q
EBioMedicine 2019 Sep;47:329-340
EBioMedicine 2019 Sep;47:329-340
DEPDC1 drives hepatocellular carcinoma cell proliferation, invasion and angiogenesis by regulating the CCL20/CCR6 signaling pathway.
Guo W, Li H, Liu H, Ma X, Yang S, Wang Z
Oncology reports 2019 Sep;42(3):1075-1089
Oncology reports 2019 Sep;42(3):1075-1089
Eukaryotic elongation factor-2 kinase regulates the cross-talk between autophagy and pyroptosis in doxorubicin-treated human melanoma cells in vitro.
Yu P, Wang HY, Tian M, Li AX, Chen XS, Wang XL, Zhang Y, Cheng Y
Acta pharmacologica Sinica 2019 Sep;40(9):1237-1244
Acta pharmacologica Sinica 2019 Sep;40(9):1237-1244
The Functional Polymorphism R129W in the BVES Gene Is Associated with Sporadic Tetralogy of Fallot in the Han Chinese Population.
Shi Y, Li Y, Wang Y, Zhuang J, Wang H, Hu M, Mo X, Yue S, Chen Y, Fan X, Chen J, Cai W, Zhu X, Wan Y, Zhong Y, Ye X, Li F, Zhou Z, Dai G, Luo R, Ocorr K, Jiang Z, Li X, Zhu P, Wu X, Yuan W
Genetic testing and molecular biomarkers 2019 Sep;23(9):601-609
Genetic testing and molecular biomarkers 2019 Sep;23(9):601-609
Ursolic acid suppresses the invasive potential of colorectal cancer cells by regulating the TGF-β1/ZEB1/miR-200c signaling pathway.
Zhang L, Cai QY, Liu J, Peng J, Chen YQ, Sferra TJ, Lin JM
Oncology letters 2019 Sep;18(3):3274-3282
Oncology letters 2019 Sep;18(3):3274-3282
2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone induced apoptosis and G1 cell cycle arrest through PI3K/AKT pathway in BEL-7402/5-FU cells.
Ji X, Wei X, Qian J, Mo X, Kai G, An F, Lu Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Sep;131:110533
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Sep;131:110533
HOXA11-AS regulates JAK-STAT pathway by miR-15a-3p/STAT3 axis to promote the growth and metastasis in liver cancer.
Wang S, Zhang S, He Y, Huang X, Hui Y, Tang Y
Journal of cellular biochemistry 2019 Sep;120(9):15941-15951
Journal of cellular biochemistry 2019 Sep;120(9):15941-15951
SARI attenuates colon inflammation by promoting STAT1 degradation in intestinal epithelial cells.
Dai L, Liu Y, Cheng L, Wang H, Lin Y, Shi G, Dong Z, Li J, Fan P, Wang Q, Su X, Zhang S, Yang Y, Hu X, Huang W, Zhou Z, Yu D, Probert C, Wei Y, Deng H
Mucosal immunology 2019 Sep;12(5):1130-1140
Mucosal immunology 2019 Sep;12(5):1130-1140
Induction of Nrf2 pathway by Dendrobium nobile Lindl. alkaloids protects against carbon tetrachloride induced acute liver injury.
Li S, Zhou J, Xu S, Li J, Liu J, Lu Y, Shi J, Zhou S, Wu Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109073
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109073
A hidden human proteome encoded by 'non-coding' genes.
Lu S, Zhang J, Lian X, Sun L, Meng K, Chen Y, Sun Z, Yin X, Li Y, Zhao J, Wang T, Zhang G, He QY
Nucleic acids research 2019 Sep 5;47(15):8111-8125
Nucleic acids research 2019 Sep 5;47(15):8111-8125
LINC01123, a c-Myc-activated long non-coding RNA, promotes proliferation and aerobic glycolysis of non-small cell lung cancer through miR-199a-5p/c-Myc axis.
Hua Q, Jin M, Mi B, Xu F, Li T, Zhao L, Liu J, Huang G
Journal of hematology & oncology 2019 Sep 5;12(1):91
Journal of hematology & oncology 2019 Sep 5;12(1):91
CDK5-dependent phosphorylation and nuclear translocation of TRIM59 promotes macroH2A1 ubiquitination and tumorigenicity.
Sang Y, Li Y, Zhang Y, Alvarez AA, Yu B, Zhang W, Hu B, Cheng SY, Feng H
Nature communications 2019 Sep 5;10(1):4013
Nature communications 2019 Sep 5;10(1):4013
Applying vibration in early postmenopausal osteoporosis promotes osteogenic differentiation of bone marrow-derived mesenchymal stem cells and suppresses postmenopausal osteoporosis progression.
Li H, Wu W, He X, Cao C, Yu X, Zeng Y, Li L
Bioscience reports 2019 Sep 30;39(9)
Bioscience reports 2019 Sep 30;39(9)
Fine particulate matters induce apoptosis via the ATM/P53/CDK2 and mitochondria apoptosis pathway triggered by oxidative stress in rat and GC-2spd cell.
Liu J, Zhang J, Ren L, Wei J, Zhu Y, Duan J, Jing L, Sun Z, Zhou X
Ecotoxicology and environmental safety 2019 Sep 30;180:280-287
Ecotoxicology and environmental safety 2019 Sep 30;180:280-287
NRF2-dependent gene expression promotes ciliogenesis and Hedgehog signaling.
Martin-Hurtado A, Martin-Morales R, Robledinos-Antón N, Blanco R, Palacios-Blanco I, Lastres-Becker I, Cuadrado A, Garcia-Gonzalo FR
Scientific reports 2019 Sep 25;9(1):13896
Scientific reports 2019 Sep 25;9(1):13896
MiR-143-3p directly targets GLUT9 to reduce uric acid reabsorption and inflammatory response of renal tubular epithelial cells.
Zhou Z, Dong Y, Zhou H, Liu J, Zhao W
Biochemical and biophysical research communications 2019 Sep 24;517(3):413-420
Biochemical and biophysical research communications 2019 Sep 24;517(3):413-420
Kinsenoside ameliorates intervertebral disc degeneration through the activation of AKT-ERK1/2-Nrf2 signaling pathway.
Wang Y, Zuo R, Wang Z, Luo L, Wu J, Zhang C, Liu M, Shi C, Zhou Y
Aging 2019 Sep 23;11(18):7961-7977
Aging 2019 Sep 23;11(18):7961-7977
Accelerated Metabolite Levels of Aerobic Glycolysis and the Pentose Phosphate Pathway Are Required for Efficient Replication of Infectious Spleen and Kidney Necrosis Virus in Chinese Perch Brain Cells.
Guo X, Wu S, Li N, Lin Q, Liu L, Liang H, Niu Y, Huang Z, Fu X
Biomolecules 2019 Sep 2;9(9)
Biomolecules 2019 Sep 2;9(9)
Long non-coding RNA, HOTAIRM1, promotes glioma malignancy by forming a ceRNA network.
Liang Q, Li X, Guan G, Xu X, Chen C, Cheng P, Cheng W, Wu A
Aging 2019 Sep 2;11(17):6805-6838
Aging 2019 Sep 2;11(17):6805-6838
Maltol (3-Hydroxy-2-methyl-4-pyrone) Slows d-Galactose-Induced Brain Aging Process by Damping the Nrf2/HO-1-Mediated Oxidative Stress in Mice.
Sha JY, Zhou YD, Yang JY, Leng J, Li JH, Hu JN, Liu W, Jiang S, Wang YP, Chen C, Li W
Journal of agricultural and food chemistry 2019 Sep 18;67(37):10342-10351
Journal of agricultural and food chemistry 2019 Sep 18;67(37):10342-10351
Exosomes derived from cardiac progenitor cells attenuate CVB3-induced apoptosis via abrogating the proliferation of CVB3 and modulating the mTOR signaling pathways.
Li X, Yang Z, Nie W, Jiang J, Li S, Li Z, Tian L, Ma X
Cell death & disease 2019 Sep 18;10(10):691
Cell death & disease 2019 Sep 18;10(10):691
Bisdemethoxycurcumin Protection of Cardiomyocyte Mainly Depends on Nrf2/HO-1 Activation Mediated by the PI3K/AKT Pathway.
Li X, Huo C, Xiao Y, Xu R, Liu Y, Jia X, Wang X
Chemical research in toxicology 2019 Sep 16;32(9):1871-1879
Chemical research in toxicology 2019 Sep 16;32(9):1871-1879
Regulatory effect of a Chinese herbal medicine formula on non-alcoholic fatty liver disease.
Yang JM, Sun Y, Wang M, Zhang XL, Zhang SJ, Gao YS, Chen L, Wu MY, Zhou L, Zhou YM, Wang Y, Zheng FJ, Li YH
World journal of gastroenterology 2019 Sep 14;25(34):5105-5119
World journal of gastroenterology 2019 Sep 14;25(34):5105-5119
Artocarmitin B enhances intracellular antioxidant capacity via activation of Nrf2 signaling pathway in human lung epithelial cells.
Wu XY, Chen XM, Zhou MX, Hu HX, Zhang JZ, Wang XN, Ren DM, Lou HX, Shen T
Chemico-biological interactions 2019 Sep 1;310:108741
Chemico-biological interactions 2019 Sep 1;310:108741
Tetrandrine and cepharanthine induce apoptosis through caspase cascade regulation, cell cycle arrest, MAPK activation and PI3K/Akt/mTOR signal modification in glucocorticoid resistant human leukemia Jurkat T cells.
Xu W, Wang X, Tu Y, Masaki H, Tanaka S, Onda K, Sugiyama K, Yamada H, Hirano T
Chemico-biological interactions 2019 Sep 1;310:108726
Chemico-biological interactions 2019 Sep 1;310:108726
Astragaloside IV protects against hyperglycemia-induced vascular endothelial dysfunction by inhibiting oxidative stress and Calpain-1 activation.
Nie Q, Zhu L, Zhang L, Leng B, Wang H
Life sciences 2019 Sep 1;232:116662
Life sciences 2019 Sep 1;232:116662
The protective effects of Ghrelin/GHSR on hippocampal neurogenesis in CUMS mice.
Huang HJ, Chen XR, Han QQ, Wang J, Pilot A, Yu R, Liu Q, Li B, Wu GC, Wang YQ, Yu J
Neuropharmacology 2019 Sep 1;155:31-43
Neuropharmacology 2019 Sep 1;155:31-43
Grouper Atg12 negatively regulates the antiviral immune response against Singapore grouper iridovirus (SGIV) infection.
Li C, Yu Y, Zhang X, Wei J, Qin Q
Fish & shellfish immunology 2019 Oct;93:702-710
Fish & shellfish immunology 2019 Oct;93:702-710
MicroRNA-182-3p negatively regulates cytokines expression by targeting TLR5M in orange-spotted grouper, Epinephelus coioides.
He L, Zhao M, Yu X, Zhao Y, Fu L, Qiao X, Lin H, Zhang Y, Li G, Li S, Lu D
Fish & shellfish immunology 2019 Oct;93:589-596
Fish & shellfish immunology 2019 Oct;93:589-596
Naringin mitigates myocardial strain and the inflammatory response in sepsis-induced myocardial dysfunction through regulation of PI3K/AKT/NF-κB pathway.
Sun LJ, Qiao W, Xiao YJ, Cui L, Wang X, Ren WD
International immunopharmacology 2019 Oct;75:105782
International immunopharmacology 2019 Oct;75:105782
Rhein inhibits ATP-triggered inflammatory responses in rheumatoid rat fibroblast-like synoviocytes.
Hu F, Zhu D, Pei W, Lee I, Zhang X, Pan L, Xu J
International immunopharmacology 2019 Oct;75:105780
International immunopharmacology 2019 Oct;75:105780
SIRT1-regulated HMGB1 release is partially involved in TLR4 signal transduction: A possible anti-neuroinflammatory mechanism of resveratrol in neonatal hypoxic-ischemic brain injury.
Le K, Chibaatar Daliv E, Wu S, Qian F, Ali AI, Yu D, Guo Y
International immunopharmacology 2019 Oct;75:105779
International immunopharmacology 2019 Oct;75:105779
USP22 Deubiquitinates CD274 to Suppress Anticancer Immunity.
Huang X, Zhang Q, Lou Y, Wang J, Zhao X, Wang L, Zhang X, Li S, Zhao Y, Chen Q, Liang T, Bai X
Cancer immunology research 2019 Oct;7(10):1580-1590
Cancer immunology research 2019 Oct;7(10):1580-1590
Overexpression of Limb-Bud and Heart (LBH) promotes angiogenesis in human glioma via VEGFA-mediated ERK signalling under hypoxia.
Jiang Y, Zhou J, Zou D, Hou D, Zhang H, Zhao J, Li L, Hu J, Zhang Y, Jing Z
EBioMedicine 2019 Oct;48:36-48
EBioMedicine 2019 Oct;48:36-48
MiR-26a promotes fracture healing of nonunion rats possibly by targeting SOSTDC1 and further activating Wnt/β-catenin signaling pathway.
Sun L, Li Z, Xue H, Ma T, Ren C, Li M, Lu Y, Sun H, Zhang K
Molecular and cellular biochemistry 2019 Oct;460(1-2):165-173
Molecular and cellular biochemistry 2019 Oct;460(1-2):165-173
Ginsenoside compound K ameliorates Alzheimer's disease in HT22 cells by adjusting energy metabolism.
Chen X, Li H, Yang Q, Lan X, Wang J, Cao Z, Shi X, Li J, Kan M, Qu X, Li N
Molecular biology reports 2019 Oct;46(5):5323-5332
Molecular biology reports 2019 Oct;46(5):5323-5332
Dioscin attenuates Bleomycin-Induced acute lung injury via inhibiting the inflammatory response in mice.
Wu ZL, Wang J
Experimental lung research 2019 Oct;45(8):236-244
Experimental lung research 2019 Oct;45(8):236-244
Propentofylline reduces mechanical allodynia and induces mitogen-activated protein kinase phosphatase-1: An experimental study in a rat model of acute incisional pain.
Yang Y, Shi Y, Jia J, Wang S, Chang H, Li M, Jin X, Wang J
Neurological research 2019 Oct;41(10):900-908
Neurological research 2019 Oct;41(10):900-908
PM(2.5) upregulates rat mesenteric arteries 5-HT(2A) receptor via inflammatory-mediated mitogen-activated protein kinases signaling pathway.
Wang R, Cao L, Shen ZX, Cao YX, Yu J
Environmental toxicology 2019 Oct;34(10):1094-1104
Environmental toxicology 2019 Oct;34(10):1094-1104
MYCT1 represses apoptosis of laryngeal cancerous cells through the MAX/miR-181a/NPM1 pathway.
Wang HT, Tong X, Zhang ZX, Sun YY, Yan W, Xu ZM, Fu WN
The FEBS journal 2019 Oct;286(19):3892-3908
The FEBS journal 2019 Oct;286(19):3892-3908
LncRNA ADPGK-AS1 regulated cell proliferation, invasion, migration and apoptosis via targeting miR-542-3p in osteosarcoma.
Luo XF, Wu XJ, Wei X, Wang AG, Wang SH, Wang JL
European review for medical and pharmacological sciences 2019 Oct;23(20):8751-8760
European review for medical and pharmacological sciences 2019 Oct;23(20):8751-8760
Berberine attenuates XRCC1-mediated base excision repair and sensitizes breast cancer cells to the chemotherapeutic drugs.
Gao X, Wang J, Li M, Wang J, Lv J, Zhang L, Sun C, Ji J, Yang W, Zhao Z, Mao W
Journal of cellular and molecular medicine 2019 Oct;23(10):6797-6804
Journal of cellular and molecular medicine 2019 Oct;23(10):6797-6804
Glycine cleavage system determines the fate of pluripotent stem cells via the regulation of senescence and epigenetic modifications.
Tian S, Feng J, Cao Y, Shen S, Cai Y, Yang D, Yan R, Wang L, Zhang H, Zhong X, Gao P
Life science alliance 2019 Oct;2(5)
Life science alliance 2019 Oct;2(5)
Cleavage and polyadenylation specific factor 4 promotes colon cancer progression by transcriptionally activating hTERT.
Yang Q, Fan W, Zheng Z, Lin S, Liu C, Wang R, Li W, Zuo Y, Sun Y, Hu S, Chen M, Guo P, Pan J, Tian C, Zhu T, Diao C, Hao J, Yu W, Li L, Li Y, Guo W, Deng W, Wu X
Biochimica et biophysica acta. Molecular cell research 2019 Oct;1866(10):1533-1543
Biochimica et biophysica acta. Molecular cell research 2019 Oct;1866(10):1533-1543
Apigenin reduces the excessive accumulation of lipids induced by palmitic acid via the AMPK signaling pathway in HepG2 cells.
Lu J, Meng Z, Cheng B, Liu M, Tao S, Guan S
Experimental and therapeutic medicine 2019 Oct;18(4):2965-2971
Experimental and therapeutic medicine 2019 Oct;18(4):2965-2971
The development of a cell-based model for the assessment of carcinogenic potential upon long-term PM2.5 exposure.
Chen S, Li D, Zhang H, Yu D, Chen R, Zhang B, Tan Y, Niu Y, Duan H, Mai B, Chen S, Yu J, Luan T, Chen L, Xing X, Li Q, Xiao Y, Dong G, Niu Y, Aschner M, Zhang R, Zheng Y, Chen W
Environment international 2019 Oct;131:104943
Environment international 2019 Oct;131:104943
Inhibition of myeloid differentiation 1 specifically in colon with antisense oligonucleotide exacerbates dextran sodium sulfate-induced colitis.
Chen X, Pan H, Li J, Zhang G, Cheng S, Zuo N, Zhao Q, Peng Z
Journal of cellular biochemistry 2019 Oct;120(10):16888-16899
Journal of cellular biochemistry 2019 Oct;120(10):16888-16899
RNA sequencing analysis of the CAL-27 cell response to over-expressed ZNF750 gene revealed an extensive regulation on cell cycle.
Liu X, Yang Y, Xu C, Yang H, Chen S, Chen H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109377
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109377
Limonin enhances the radiosensitivity of nasopharyngeal carcinoma cells via attenuating Stat3-induced cell stemness.
Gao L, Sang JZ, Cao H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109366
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109366
SIRT1 activation attenuates cardiac fibrosis by endothelial-to-mesenchymal transition.
Liu ZH, Zhang Y, Wang X, Fan XF, Zhang Y, Li X, Gong YS, Han LP
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109227
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109227
Inhibition of high mobility group box 1 (HMGB1) attenuates podocyte apoptosis and epithelial-mesenchymal transition by regulating autophagy flux.
Jin J, Gong J, Zhao L, Zhang H, He Q, Jiang X
Journal of diabetes 2019 Oct;11(10):826-836
Journal of diabetes 2019 Oct;11(10):826-836
MiR-16a Regulates Milk Fat Metabolism by Targeting Large Tumor Suppressor Kinase 1 (LATS1) in Bovine Mammary Epithelial Cells.
Chen Z, Chu S, Wang X, Sun Y, Xu T, Mao Y, Loor JJ, Yang Z
Journal of agricultural and food chemistry 2019 Oct 9;67(40):11167-11178
Journal of agricultural and food chemistry 2019 Oct 9;67(40):11167-11178
Viral N(6)-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus.
Xue M, Zhao BS, Zhang Z, Lu M, Harder O, Chen P, Lu Z, Li A, Ma Y, Xu Y, Liang X, Zhou J, Niewiesk S, Peeples ME, He C, Li J
Nature communications 2019 Oct 9;10(1):4595
Nature communications 2019 Oct 9;10(1):4595
CircWHSC1 promotes ovarian cancer progression by regulating MUC1 and hTERT through sponging miR-145 and miR-1182.
Zong ZH, Du YP, Guan X, Chen S, Zhao Y
Journal of experimental & clinical cancer research : CR 2019 Oct 30;38(1):437
Journal of experimental & clinical cancer research : CR 2019 Oct 30;38(1):437
Oxidative stress-induced cellular senescence desensitizes cell growth and migration of vascular smooth muscle cells through down-regulation of platelet-derived growth factor receptor-beta.
Pan CH, Chen CJ, Shih CM, Wang MF, Wang JY, Wu CH
Aging 2019 Oct 3;11(19):8085-8102
Aging 2019 Oct 3;11(19):8085-8102
Tumor vasculature remolding by thalidomide increases delivery and efficacy of cisplatin.
Shen Y, Li S, Wang X, Wang M, Tian Q, Yang J, Wang J, Wang B, Liu P, Yang J
Journal of experimental & clinical cancer research : CR 2019 Oct 28;38(1):427
Journal of experimental & clinical cancer research : CR 2019 Oct 28;38(1):427
Knockout of neutrophil elastase protects against western diet induced nonalcoholic steatohepatitis in mice by regulating hepatic ceramides metabolism.
Chen J, Liang B, Bian D, Luo Y, Yang J, Li Z, Zhuang Z, Zang S, Shi J
Biochemical and biophysical research communications 2019 Oct 22;518(4):691-697
Biochemical and biophysical research communications 2019 Oct 22;518(4):691-697
SPOP suppresses pancreatic cancer progression by promoting the degradation of NANOG.
Tan P, Xu Y, Du Y, Wu L, Guo B, Huang S, Zhu J, Li B, Lin F, Yao L
Cell death & disease 2019 Oct 17;10(11):794
Cell death & disease 2019 Oct 17;10(11):794
Circ-Spidr enhances axon regeneration after peripheral nerve injury.
Mao S, Huang T, Chen Y, Shen L, Zhou S, Zhang S, Yu B
Cell death & disease 2019 Oct 17;10(11):787
Cell death & disease 2019 Oct 17;10(11):787
γ-Oryzanol alleviates acetaminophen-induced liver injury: roles of modulating AMPK/GSK3β/Nrf2 and NF-κB signaling pathways.
Shu G, Qiu Y, Hao J, Fu Q, Deng X
Food & function 2019 Oct 16;10(10):6858-6872
Food & function 2019 Oct 16;10(10):6858-6872
Six1 is negatively correlated with poor prognosis and reduces 5-fluorouracil sensitivity via attenuating the stemness of hepatocellular carcinoma cells.
Chen K, Wei H, Pan J, Chen Z, Pan D, Gao T, Huang J, Huang M, Ou M, Zhong W
European journal of pharmacology 2019 Oct 15;861:172599
European journal of pharmacology 2019 Oct 15;861:172599
Angiotensin II deteriorates advanced atherosclerosis by promoting MerTK cleavage and impairing efferocytosis through the AT(1)R/ROS/p38 MAPK/ADAM17 pathway.
Zhang Y, Wang Y, Zhou D, Zhang LS, Deng FX, Shu S, Wang LJ, Wu Y, Guo N, Zhou J, Yuan ZY
American journal of physiology. Cell physiology 2019 Oct 1;317(4):C776-C787
American journal of physiology. Cell physiology 2019 Oct 1;317(4):C776-C787
Melatonin Receptor Mel1b- and Mel1c-mediated Green Light Induced the Secretion of Growth Hormone in Anterior Pituitary of Chicks.
Yue L, Qin X, Liu X, Wang Z, Dong Y, Chen Y, Cao J
Photochemistry and photobiology 2019 Nov;95(6):1387-1394
Photochemistry and photobiology 2019 Nov;95(6):1387-1394
A novel RING finger protein CqRNF152-like with self-ubiquitination activity inhibits white spot syndrome virus infection in a crustacean Cherax quadricarinatus.
Zheng SC, Chang XJ, Li WD, Wang H, Guo LM, Wang KJ, Liu HP
Fish & shellfish immunology 2019 Nov;94:934-943
Fish & shellfish immunology 2019 Nov;94:934-943
Zinc alleviates arsenism in common carp: Varied change profiles of cytokines and tight junction proteins among two intestinal segments.
Zhao H, Wang Y, Yang X, Fei D, Mu M, Guo M, Yu H, Xing M
Fish & shellfish immunology 2019 Nov;94:761-768
Fish & shellfish immunology 2019 Nov;94:761-768
Molecular cloning, expression and functional analysis of Atg16L1 from orange-spotted grouper (Epinephelus coioides).
Li C, Wang L, Zhang X, Wei J, Qin Q
Fish & shellfish immunology 2019 Nov;94:113-121
Fish & shellfish immunology 2019 Nov;94:113-121
Screening candidate microR-15a- IRAK2 regulatory pairs for predicting the response to Staphylococcus aureus-induced mastitis in dairy cows.
Chen Z, Zhou J, Wang X, Zhang Y, Lu X, Fan Y, Mao Y, Loor JJ, Yang Z
The Journal of dairy research 2019 Nov;86(4):425-431
The Journal of dairy research 2019 Nov;86(4):425-431
Tumor-suppressive activity of Hnf1β in Wilms' tumor.
Liu Y, Kanyomse Q, Xie Y
Bioscience, biotechnology, and biochemistry 2019 Nov;83(11):2008-2015
Bioscience, biotechnology, and biochemistry 2019 Nov;83(11):2008-2015
The protective effects of L-carnitine on myocardial ischaemia-reperfusion injury in patients with rheumatic valvular heart disease undergoing CPB surgery are associated with the suppression of NF-κB pathway and the activation of Nrf2 pathway.
Li M, Xu S, Geng Y, Sun L, Wang R, Yan Y, Wang H, Li Y, Yi Q, Zhang Y, Hao J, Deng C, Li W, Xue L
Clinical and experimental pharmacology & physiology 2019 Nov;46(11):1001-1012
Clinical and experimental pharmacology & physiology 2019 Nov;46(11):1001-1012
ADP-ribosyltransferase PARP11 modulates the interferon antiviral response by mono-ADP-ribosylating the ubiquitin E3 ligase β-TrCP.
Guo T, Zuo Y, Qian L, Liu J, Yuan Y, Xu K, Miao Y, Feng Q, Chen X, Jin L, Zhang L, Dong C, Xiong S, Zheng H
Nature microbiology 2019 Nov;4(11):1872-1884
Nature microbiology 2019 Nov;4(11):1872-1884
Nonviral Delivery of GRIM-19 Gene Inhibits Tumor Growth with Reduced Local and Systemic Complications.
Xu Y, Wang X, Guo B, Wang D, Kalvakolanu DV, Chen X, Tang J, Zhang L, Yang Q
Human gene therapy 2019 Nov;30(11):1419-1430
Human gene therapy 2019 Nov;30(11):1419-1430
Long-term exposure of 4-hydroxyestradiol induces the cancer cell characteristics via upregulating CYP1B1 in MCF-10A cells.
Lanxiang W, Bin W, Ge X, Yutang H, Chunjie W, Honghao Z
Toxicology mechanisms and methods 2019 Nov;29(9):686-692
Toxicology mechanisms and methods 2019 Nov;29(9):686-692
Isoflurane produces antidepressant effects inducing BDNF-TrkB signaling in CUMS mice.
Zhang SS, Tian YH, Jin SJ, Wang WC, Zhao JX, Si XM, Zhang L, Xu H, Jin JY
Psychopharmacology 2019 Nov;236(11):3301-3315
Psychopharmacology 2019 Nov;236(11):3301-3315
Astragaloside IV alleviates myocardial damage induced by type 2 diabetes via improving energy metabolism.
Zhang Z, Wang J, Zhu Y, Zhang H, Wang H
Molecular medicine reports 2019 Nov;20(5):4612-4622
Molecular medicine reports 2019 Nov;20(5):4612-4622
Deep Protein Methylation Profiling by Combined Chemical and Immunoaffinity Approaches Reveals Novel PRMT1 Targets.
Hartel NG, Chew B, Qin J, Xu J, Graham NA
Molecular & cellular proteomics : MCP 2019 Nov;18(11):2149-2164
Molecular & cellular proteomics : MCP 2019 Nov;18(11):2149-2164
Repurposing of the anti-helminthic drug niclosamide to treat melanoma and pulmonary metastasis via the STAT3 signaling pathway.
Zhu Y, Zuo W, Chen L, Bian S, Jing J, Gan C, Wu X, Liu H, Su X, Hu W, Guo Y, Wang Y, Ye T
Biochemical pharmacology 2019 Nov;169:113610
Biochemical pharmacology 2019 Nov;169:113610
Increased Tim-3 expression alleviates liver injury by regulating macrophage activation in MCD-induced NASH mice.
Du X, Wu Z, Xu Y, Liu Y, Liu W, Wang T, Li C, Zhang C, Yi F, Gao L, Liang X, Ma C
Cellular & molecular immunology 2019 Nov;16(11):878-886
Cellular & molecular immunology 2019 Nov;16(11):878-886
LNRRIL6, a novel long noncoding RNA, protects colorectal cancer cells by activating the IL-6-STAT3 pathway.
Wang J, Zhou J, Jiang C, Zheng J, Namba H, Chi P, Asakawa T
Molecular oncology 2019 Nov;13(11):2344-2360
Molecular oncology 2019 Nov;13(11):2344-2360
Inhibition of p53 and/or AKT as a new therapeutic approach specifically targeting ALT cancers.
Ge Y, Wu S, Zhang Z, Li X, Li F, Yan S, Liu H, Huang J, Zhao Y
Protein & cell 2019 Nov;10(11):808-824
Protein & cell 2019 Nov;10(11):808-824
O-GlcNAcylation of Thr(12)/Ser(56) in short-form O-GlcNAc transferase (sOGT) regulates its substrate selectivity.
Liu L, Li L, Ma C, Shi Y, Liu C, Xiao Z, Zhang Y, Tian F, Gao Y, Zhang J, Ying W, Wang PG, Zhang L
The Journal of biological chemistry 2019 Nov 8;294(45):16620-16633
The Journal of biological chemistry 2019 Nov 8;294(45):16620-16633
LncRNA GABPB1-AS1 and GABPB1 regulate oxidative stress during erastin-induced ferroptosis in HepG2 hepatocellular carcinoma cells.
Qi W, Li Z, Xia L, Dai J, Zhang Q, Wu C, Xu S
Scientific reports 2019 Nov 7;9(1):16185
Scientific reports 2019 Nov 7;9(1):16185
Porcine Circovirus Type 2 Induces Single Immunoglobulin Interleukin-1 Related Receptor (SIGIRR) Downregulation to Promote Interleukin-1β Upregulation in Porcine Alveolar Macrophage.
Yang S, Liu B, Yin S, Shang Y, Zhang X, Khan MUZ, Liu X, Cai J
Viruses 2019 Nov 3;11(11)
Viruses 2019 Nov 3;11(11)
Dietary Stevioside Supplementation Alleviates Lipopolysaccharide-Induced Intestinal Mucosal Damage through Anti-Inflammatory and Antioxidant Effects in Broiler Chickens.
Jiang J, Qi L, Lv Z, Jin S, Wei X, Shi F
Antioxidants (Basel, Switzerland) 2019 Nov 21;8(12)
Antioxidants (Basel, Switzerland) 2019 Nov 21;8(12)
Mulberry leaf reduces inflammation and insulin resistance in type 2 diabetic mice by TLRs and insulin Signalling pathway.
Tian S, Wang M, Liu C, Zhao H, Zhao B
BMC complementary and alternative medicine 2019 Nov 21;19(1):326
BMC complementary and alternative medicine 2019 Nov 21;19(1):326
Inhibition of PTP1B blocks pancreatic cancer progression by targeting the PKM2/AMPK/mTOC1 pathway.
Xu Q, Wu N, Li X, Guo C, Li C, Jiang B, Wang H, Shi D
Cell death & disease 2019 Nov 19;10(12):874
Cell death & disease 2019 Nov 19;10(12):874
Self-Assembled saRNA Delivery System Based on Rolling Circle Transcription for Aptamer-Targeting Cancer Therapy.
Wang T, Hong S, Luo Y, Lv H, Zhang Y, Pei R
ACS applied bio materials 2019 Nov 18;2(11):4737-4746
ACS applied bio materials 2019 Nov 18;2(11):4737-4746
Tissue plasminogen activator disrupts the blood-brain barrier through increasing the inflammatory response mediated by pericytes after cerebral ischemia.
Yang E, Cai Y, Yao X, Liu J, Wang Q, Jin W, Wu Q, Fan W, Qiu L, Kang C, Wu J
Aging 2019 Nov 18;11(22):10167-10182
Aging 2019 Nov 18;11(22):10167-10182
Chitosan Oligosaccharide Attenuates Nonalcoholic Fatty Liver Disease Induced by High Fat Diet through Reducing Lipid Accumulation, Inflammation and Oxidative Stress in C57BL/6 Mice.
Tao W, Sun W, Liu L, Wang G, Xiao Z, Pei X, Wang M
Marine drugs 2019 Nov 16;17(11)
Marine drugs 2019 Nov 16;17(11)
Cardioprotective effects of galectin-3 inhibition against ischemia/reperfusion injury.
Mo D, Tian W, Zhang HN, Feng YD, Sun Y, Quan W, Hao XW, Wang XY, Liu XX, Li C, Cao W, Liu WJ, Li XQ
European journal of pharmacology 2019 Nov 15;863:172701
European journal of pharmacology 2019 Nov 15;863:172701
Anti-osteoporosis effects of osteoking via reducing reactive oxygen species.
Qin D, Zhang H, Zhang H, Sun T, Zhao H, Lee WH
Journal of ethnopharmacology 2019 Nov 15;244:112045
Journal of ethnopharmacology 2019 Nov 15;244:112045
Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications.
Ward CC, Kleinman JI, Brittain SM, Lee PS, Chung CYS, Kim K, Petri Y, Thomas JR, Tallarico JA, McKenna JM, Schirle M, Nomura DK
ACS chemical biology 2019 Nov 15;14(11):2430-2440
ACS chemical biology 2019 Nov 15;14(11):2430-2440
Epithelial and interstitial Notch1 activity contributes to the myofibroblastic phenotype and fibrosis.
Hong W, Zhang G, Lu H, Guo Y, Zheng S, Zhu H, Xiao Y, Papa APD, Wu C, Sun L, Chen B, Bai Y
Cell communication and signaling : CCS 2019 Nov 12;17(1):145
Cell communication and signaling : CCS 2019 Nov 12;17(1):145
Dengue Virus M Protein Promotes NLRP3 Inflammasome Activation To Induce Vascular Leakage in Mice.
Pan P, Zhang Q, Liu W, Wang W, Lao Z, Zhang W, Shen M, Wan P, Xiao F, Liu F, Zhang W, Tan Q, Liu X, Wu K, Liu Y, Li G, Wu J
Journal of virology 2019 Nov 1;93(21)
Journal of virology 2019 Nov 1;93(21)
Epigenetic Memory Is Involved in the Persistent Alterations of Drug-Processing Genes in Adult Mice Due to PCN-Activated PXR During Early Life.
Wang P, Liu G, Nie Y, Han S, Li J, Zhong XB, Zhang L
Toxicological sciences : an official journal of the Society of Toxicology 2019 Nov 1;172(1):98-108
Toxicological sciences : an official journal of the Society of Toxicology 2019 Nov 1;172(1):98-108
Recombinant porcine NK-lysin inhibits the invasion of hepatocellular carcinoma cells in vitro.
Khan A, Fan K, Sun N, Yin W, Sun Y, Sun P, Jahejo AR, Li H
International journal of biological macromolecules 2019 Nov 1;140:1249-1259
International journal of biological macromolecules 2019 Nov 1;140:1249-1259
Hepatocyte nuclear factor 1 alpha (HNF1A) regulates transcription of O-GlcNAc transferase in a negative feedback mechanism.
Zhang C, Xie F, Li L, Zhang C, Zhang Y, Ying W, Liu L, Yan X, Yin F, Zhang L
FEBS letters 2019 May;593(10):1050-1060
FEBS letters 2019 May;593(10):1050-1060
Degradation of Caytaxin Causes Learning and Memory Deficits via Activation of DAPK1 in Aging.
Guo Y, Li H, Ke X, Deng M, Wu Z, Cai Y, Afewerky HK, Zhang X, Pei L, Lu Y
Molecular neurobiology 2019 May;56(5):3368-3379
Molecular neurobiology 2019 May;56(5):3368-3379
ZW290 Increases Cold Tolerance by Inducing Thermogenesis via the Upregulation of Uncoupling Protein 1 in Brown Adipose Tissue In Vitro and In Vivo.
Wang N, Lu HY, Li X, Du YJ, Meng WH, Ding HW, Zhao QC
Lipids 2019 May;54(5):265-276
Lipids 2019 May;54(5):265-276
Inhibition of PI3K/mTOR increased the sensitivity of hepatocellular carcinoma cells to cisplatin via interference with mitochondrial-lysosomal crosstalk.
Sheng J, Shen L, Sun L, Zhang X, Cui R, Wang L
Cell proliferation 2019 May;52(3):e12609
Cell proliferation 2019 May;52(3):e12609
Homeodomain-interacting protein kinase 2 suppresses proliferation and aerobic glycolysis via ERK/cMyc axis in pancreatic cancer.
Qin Y, Hu Q, Ji S, Xu J, Dai W, Liu W, Xu W, Sun Q, Zhang Z, Ni Q, Yu X, Zhang B, Xu X
Cell proliferation 2019 May;52(3):e12603
Cell proliferation 2019 May;52(3):e12603
Moderate- and Low-Dose of Atorvastatin Alleviate Cognition Impairment Induced by High-Fat Diet via Sirt1 Activation.
Liu H, Yang J, Wang K, Niu T, Huang D
Neurochemical research 2019 May;44(5):1065-1078
Neurochemical research 2019 May;44(5):1065-1078
Apoptosis and cell cycle arrest of hepatocellular carcinoma spheroids treated by an alternating electric field.
Huang CH, Lei KF, Tsang NM
Biotechnology progress 2019 May;35(3):e2787
Biotechnology progress 2019 May;35(3):e2787
[6]-Gingerol enhances the cisplatin sensitivity of gastric cancer cells through inhibition of proliferation and invasion via PI3K/AKT signaling pathway.
Luo Y, Zha L, Luo L, Chen X, Zhang Q, Gao C, Zhuang X, Yuan S, Qiao T
Phytotherapy research : PTR 2019 May;33(5):1353-1362
Phytotherapy research : PTR 2019 May;33(5):1353-1362
5-aminolevulinic acid photodynamic therapy reduces HPV viral load via autophagy and apoptosis by modulating Ras/Raf/MEK/ERK and PI3K/AKT pathways in HeLa cells.
Xie J, Wang S, Li Z, Ao C, Wang J, Wang L, Peng X, Zeng K
Journal of photochemistry and photobiology. B, Biology 2019 May;194:46-55
Journal of photochemistry and photobiology. B, Biology 2019 May;194:46-55
A novel function of anaphase promoting complex subunit 10 in tumor progression in non-small cell lung cancer.
Wang Y, Han T, Gan M, Guo M, Xie C, Jin J, Zhang S, Wang P, Cao J, Wang JB
Cell cycle (Georgetown, Tex.) 2019 May;18(9):1019-1032
Cell cycle (Georgetown, Tex.) 2019 May;18(9):1019-1032
Nano hydroxyapatite induces glioma cell apoptosis by suppressing NF-κB signaling pathway.
Guo G, Tian A, Lan X, Fu C, Yan Z, Wang C
Experimental and therapeutic medicine 2019 May;17(5):4080-4088
Experimental and therapeutic medicine 2019 May;17(5):4080-4088
Porcine circovirus type 2 ORF5 protein induces endoplasmic reticulum stress and unfolded protein response in porcine alveolar macrophages.
Ouyang Y, Xu L, Lv J, Hou Y, Fan Z, Xu P, Jiang Y, Wu M, Li R, Zhang Y, Guo K
Archives of virology 2019 May;164(5):1323-1334
Archives of virology 2019 May;164(5):1323-1334
TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response.
Wang P, Deng J, Dong J, Liu J, Bigio EH, Mesulam M, Wang T, Sun L, Wang L, Lee AY, McGee WA, Chen X, Fushimi K, Zhu L, Wu JY
PLoS genetics 2019 May;15(5):e1007947
PLoS genetics 2019 May;15(5):e1007947
Heat shock factor 1 in cancer-associated fibroblasts is a potential prognostic factor and drives progression of oral squamous cell carcinoma.
Wang Q, Zhang YC, Zhu LF, Pan L, Yu M, Shen WL, Li B, Zhang W, Liu LK
Cancer science 2019 May;110(5):1790-1803
Cancer science 2019 May;110(5):1790-1803
LncRNA TPT1-AS1 promotes tumorigenesis and metastasis in epithelial ovarian cancer by inducing TPT1 expression.
Wu W, Gao H, Li X, Zhu Y, Peng S, Yu J, Zhan G, Wang J, Liu N, Guo X
Cancer science 2019 May;110(5):1587-1598
Cancer science 2019 May;110(5):1587-1598
Highly Selective Protein Tyrosine Phosphatase Inhibitor, 2,2',3,3'-Tetrabromo-4,4',5,5'-tetrahydroxydiphenylmethane, Ameliorates Type 2 Diabetes Mellitus in BKS db Mice.
Li C, Luo J, Guo S, Jia X, Guo C, Li X, Xu Q, Shi D
Molecular pharmaceutics 2019 May 6;16(5):1839-1850
Molecular pharmaceutics 2019 May 6;16(5):1839-1850
Adipose HuR protects against diet-induced obesity and insulin resistance.
Li J, Gong L, Liu S, Zhang Y, Zhang C, Tian M, Lu H, Bu P, Yang J, Ouyang C, Jiang X, Wu J, Zhang Y, Min Q, Zhang C, Zhang W
Nature communications 2019 May 30;10(1):2375
Nature communications 2019 May 30;10(1):2375
Canagliflozin inhibits growth of hepatocellular carcinoma via blocking glucose-influx-induced β-catenin activation.
Hung MH, Chen YL, Chen LJ, Chu PY, Hsieh FS, Tsai MH, Shih CT, Chao TI, Huang CY, Chen KF
Cell death & disease 2019 May 29;10(6):420
Cell death & disease 2019 May 29;10(6):420
Fucoidan A2 from the Brown Seaweed Ascophyllum nodosum Lowers Lipid by Improving Reverse Cholesterol Transport in C57BL/6J Mice Fed a High-Fat Diet.
Yang Z, Liu G, Wang Y, Yin J, Wang J, Xia B, Li T, Yang X, Hou P, Hu S, Song W, Guo S
Journal of agricultural and food chemistry 2019 May 22;67(20):5782-5791
Journal of agricultural and food chemistry 2019 May 22;67(20):5782-5791
Estrogen negatively regulates the renal epithelial sodium channel (ENaC) by promoting Derlin-1 expression and AMPK activation.
Zhang X, Ge Y, Bukhari AA, Zhu Q, Shen Y, Li M, Sun H, Su D, Liang X
Experimental & molecular medicine 2019 May 21;51(5):1-12
Experimental & molecular medicine 2019 May 21;51(5):1-12
Phosphatase of regenerating liver sensitizes MET to functional activation by hepatocyte growth factor.
Kojima T, Funato Y, Miki H
The Biochemical journal 2019 May 21;476(10):1419-1431
The Biochemical journal 2019 May 21;476(10):1419-1431
Triptolide prevents proliferation and migration of Esophageal Squamous Cell Cancer via MAPK/ERK signaling pathway.
Yanchun M, Yi W, Lu W, Yu Q, Jian Y, Pengzhou K, Ting Y, Hongyi L, Fang W, Xiaolong C, Yongping C
European journal of pharmacology 2019 May 15;851:43-51
European journal of pharmacology 2019 May 15;851:43-51
Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs.
Jia YN, Peng YL, Zhao YP, Cheng XF, Zhou Y, Chai CL, Zeng LS, Pan MH, Xu L
Journal of agricultural and food chemistry 2019 May 15;67(19):5521-5529
Journal of agricultural and food chemistry 2019 May 15;67(19):5521-5529
MiR-34s negatively regulate homologous recombination through targeting RAD51.
Chen S, Liu R, Wang Q, Qi Z, Hu Y, Zhou P, Wang Z
Archives of biochemistry and biophysics 2019 May 15;666:73-82
Archives of biochemistry and biophysics 2019 May 15;666:73-82
Gambogic acid attenuates liver fibrosis by inhibiting the PI3K/AKT and MAPK signaling pathways via inhibiting HSP90.
Yu Z, Jv Y, Cai L, Tian X, Huo X, Wang C, Zhang B, Sun C, Ning J, Feng L, Zhang H, Ma X
Toxicology and applied pharmacology 2019 May 15;371:63-73
Toxicology and applied pharmacology 2019 May 15;371:63-73
Meningitic Escherichia coli-induced upregulation of PDGF-B and ICAM-1 aggravates blood-brain barrier disruption and neuroinflammatory response.
Yang RC, Qu XY, Xiao SY, Li L, Xu BJ, Fu JY, Lv YJ, Amjad N, Tan C, Kim KS, Chen HC, Wang XR
Journal of neuroinflammation 2019 May 15;16(1):101
Journal of neuroinflammation 2019 May 15;16(1):101
Sodium ferulate protects against influenza virus infection by activation of the TLR7/9-MyD88-IRF7 signaling pathway and inhibition of the NF-κB signaling pathway.
Zhu Y, Shao Y, Qu X, Guo J, Yang J, Zhou Z, Wang S
Biochemical and biophysical research communications 2019 May 14;512(4):793-798
Biochemical and biophysical research communications 2019 May 14;512(4):793-798
A maternal high-fat, high-sucrose diet induces transgenerational cardiac mitochondrial dysfunction independently of maternal mitochondrial inheritance.
Ferey JLA, Boudoures AL, Reid M, Drury A, Scheaffer S, Modi Z, Kovacs A, Pietka T, DeBosch BJ, Thompson MD, Diwan A, Moley KH
American journal of physiology. Heart and circulatory physiology 2019 May 1;316(5):H1202-H1210
American journal of physiology. Heart and circulatory physiology 2019 May 1;316(5):H1202-H1210
Histone deacetylase 7 inhibits plakoglobin expression to promote lung cancer cell growth and metastasis.
Sang Y, Sun L, Wu Y, Yuan W, Liu Y, Li SW
International journal of oncology 2019 Mar;54(3):1112-1122
International journal of oncology 2019 Mar;54(3):1112-1122
Overexpression of ERBB4 rejuvenates aged mesenchymal stem cells and enhances angiogenesis via PI3K/AKT and MAPK/ERK pathways.
Liang X, Ding Y, Lin F, Zhang Y, Zhou X, Meng Q, Lu X, Jiang G, Zhu H, Chen Y, Lian Q, Fan H, Liu Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Mar;33(3):4559-4570
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Mar;33(3):4559-4570
In utero exposure to PM2.5 during gestation caused adult cardiac hypertrophy through histone acetylation modification.
Wu X, Pan B, Liu L, Zhao W, Zhu J, Huang X, Tian J
Journal of cellular biochemistry 2019 Mar;120(3):4375-4384
Journal of cellular biochemistry 2019 Mar;120(3):4375-4384
Nuciferine inhibits the progression of glioblastoma by suppressing the SOX2-AKT/STAT3-Slug signaling pathway.
Li Z, Chen Y, An T, Liu P, Zhu J, Yang H, Zhang W, Dong T, Jiang J, Zhang Y, Jiang M, Yang X
Journal of experimental & clinical cancer research : CR 2019 Mar 29;38(1):139
Journal of experimental & clinical cancer research : CR 2019 Mar 29;38(1):139
Cysteine Dioxygenase Regulates the Epithelial Morphogenesis of Mammary Gland via Cysteine Sulfinic Acid.
Zhao J, Han Y, Ma X, Zhou Y, Yuan S, Shen Q, Ye G, Liu H, Fu P, Zhang G, Qiao B, Liu A
iScience 2019 Mar 29;13:173-189
iScience 2019 Mar 29;13:173-189
The nanoparticle-facilitated autophagy inhibition of cancer stem cells for improved chemotherapeutic effects on glioblastomas.
Lu L, Shen X, Tao B, Lin C, Li K, Luo Z, Cai K
Journal of materials chemistry. B 2019 Mar 28;7(12):2054-2062
Journal of materials chemistry. B 2019 Mar 28;7(12):2054-2062
Curcumin and Resveratrol Regulate Intestinal Bacteria and Alleviate Intestinal Inflammation in Weaned Piglets.
Gan Z, Wei W, Li Y, Wu J, Zhao Y, Zhang L, Wang T, Zhong X
Molecules (Basel, Switzerland) 2019 Mar 28;24(7)
Molecules (Basel, Switzerland) 2019 Mar 28;24(7)
Effect of Stereochemical Configuration on the Transport and Metabolism of Catechins from Green Tea across Caco-2 Monolayers.
Ai Z, Liu S, Qu F, Zhang H, Chen Y, Ni D
Molecules (Basel, Switzerland) 2019 Mar 26;24(6)
Molecules (Basel, Switzerland) 2019 Mar 26;24(6)
RNA-Binding Motif Protein 24 (RBM24) Is Involved in Pregenomic RNA Packaging by Mediating Interaction between Hepatitis B Virus Polymerase and the Epsilon Element.
Yao Y, Yang B, Chen Y, Wang H, Hu X, Zhou Y, Gao X, Lu M, Niu J, Wen Z, Wu C, Chen X
Journal of virology 2019 Mar 15;93(6)
Journal of virology 2019 Mar 15;93(6)
GRASP depletion-mediated Golgi destruction decreases cell adhesion and migration via the reduction of α5β1 integrin.
Ahat E, Xiang Y, Zhang X, Bekier ME 2nd, Wang Y
Molecular biology of the cell 2019 Mar 15;30(6):766-777
Molecular biology of the cell 2019 Mar 15;30(6):766-777
The role of adenosine in up-regulation of p38 MAPK and ERK during limb ischemic preconditioning-induced brain ischemic tolerance.
Yuan Q, Jia HX, Li SQ, Xiao-Zhang, Wu YJ, Feng L, Liu XL, Sun XC, Li WB
Brain research 2019 Mar 15;1707:172-183
Brain research 2019 Mar 15;1707:172-183
Purification of cross-linked RNA-protein complexes by phenol-toluol extraction.
Urdaneta EC, Vieira-Vieira CH, Hick T, Wessels HH, Figini D, Moschall R, Medenbach J, Ohler U, Granneman S, Selbach M, Beckmann BM
Nature communications 2019 Mar 1;10(1):990
Nature communications 2019 Mar 1;10(1):990
CD30 ligand deficiency accelerates glioma progression by promoting the formation of tumor immune microenvironment.
Duan J, Gao Y, Zhang X, Wang X, Wang B, Meng X, Yoshikai Y, Wang Y, Sun X
International immunopharmacology 2019 Jun;71:350-360
International immunopharmacology 2019 Jun;71:350-360
Deficiency of ZnT8 Promotes Adiposity and Metabolic Dysfunction by Increasing Peripheral Serotonin Production.
Mao Z, Lin H, Su W, Li J, Zhou M, Li Z, Zhou B, Yang Q, Zhou M, Pan K, He J, Zhang W
Diabetes 2019 Jun;68(6):1197-1209
Diabetes 2019 Jun;68(6):1197-1209
MicroRNA-145 regulates immune cytokines via targeting FSCN1 in Staphylococcus aureus-induced mastitis in dairy cows.
Chen Z, Xu X, Tan T, Chen D, Liang H, Sun K, Li M, Zhang H, Mao Y, Yang Z
Reproduction in domestic animals = Zuchthygiene 2019 Jun;54(6):882-891
Reproduction in domestic animals = Zuchthygiene 2019 Jun;54(6):882-891
ERβ modulates genistein's cisplatin-enhancing activities in breast cancer MDA-MB-231 cells via P53-independent pathway.
Liu R, Xu X, Liang C, Chen X, Yu X, Zhong H, Xu W, Cheng Y, Wang W, Wu Y, Yu L, Hu X
Molecular and cellular biochemistry 2019 Jun;456(1-2):205-216
Molecular and cellular biochemistry 2019 Jun;456(1-2):205-216
B-lymphocyte-intrinsic and -extrinsic defects in secretory immunoglobulin A production in the neural crest-conditional deletion of endothelin receptor B model of Hirschsprung-associated enterocolitis.
Medrano G, Cailleux F, Guan P, Kuruvilla K, Barlow-Anacker AJ, Gosain A
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jun;33(6):7615-7624
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jun;33(6):7615-7624
p62 aggregates mediated Caspase 8 activation is responsible for progression of ovarian cancer.
Yan XY, Zhong XR, Yu SH, Zhang LC, Liu YN, Zhang Y, Sun LK, Su J
Journal of cellular and molecular medicine 2019 Jun;23(6):4030-4042
Journal of cellular and molecular medicine 2019 Jun;23(6):4030-4042
Age-dependent expression of the vitamin D receptor and the protective effect of vitamin D receptor activation on H(2)O(2)-induced apoptosis in rat intervertebral disc cells.
Tong T, Liu Z, Zhang H, Sun J, Zhang D, Wang F, Miao D, Shen Y
The Journal of steroid biochemistry and molecular biology 2019 Jun;190:126-138
The Journal of steroid biochemistry and molecular biology 2019 Jun;190:126-138
TUSC3 as a potential biomarker for prognosis in clear cell renal cell carcinoma.
Yan Y, Chen Z, Liao Y, Zhou J
Oncology letters 2019 Jun;17(6):5073-5079
Oncology letters 2019 Jun;17(6):5073-5079
An NLRP3 inflammasome-triggered cytokine storm contributes to Streptococcal toxic shock-like syndrome (STSLS).
Lin L, Xu L, Lv W, Han L, Xiang Y, Fu L, Jin M, Zhou R, Chen H, Zhang A
PLoS pathogens 2019 Jun;15(6):e1007795
PLoS pathogens 2019 Jun;15(6):e1007795
Decreased S1P and SPHK2 are involved in pancreatic acinar cell injury.
Xiao J, Lin H, Liu B, Xia Z, Zhang J, Jin J
Biomarkers in medicine 2019 Jun;13(8):627-637
Biomarkers in medicine 2019 Jun;13(8):627-637
A promising therapeutic option for diabetic bladder dysfunction: Adipose tissue-derived stem cells pretreated by defocused low-energy shock wave.
Zhang H, Zhao Y, Wang M, Song W, Sun P, Jin X
Journal of tissue engineering and regenerative medicine 2019 Jun;13(6):986-996
Journal of tissue engineering and regenerative medicine 2019 Jun;13(6):986-996
High-level expression of PRSS3 correlates with metastasis and poor prognosis in patients with gastric cancer.
Wang F, Hu YL, Feng Y, Guo YB, Liu YF, Mao QS, Xue WJ
Journal of surgical oncology 2019 Jun;119(8):1108-1121
Journal of surgical oncology 2019 Jun;119(8):1108-1121
Recombinant human arginase I elicited immunosuppression in activated macrophages through inhibiting autophagy.
Wang Z, Song P, Li Y, Wang S, Fan J, Zhang X, Luan J, Chen W, Wang Y, Liu P, Ju D
Applied microbiology and biotechnology 2019 Jun;103(12):4825-4838
Applied microbiology and biotechnology 2019 Jun;103(12):4825-4838
Rh type C-glycoprotein functions as a novel tumor suppressor gene by inhibiting tumorigenicity and metastasis in head and neck squamous cell carcinoma.
Xu W, Zou H, Wei Z, Song C, Tang C, Yin X, Wang Y, Han S, Cai Y, Han W
Aging 2019 Jun 6;11(11):3601-3623
Aging 2019 Jun 6;11(11):3601-3623
Mechanism of Snhg8/miR-384/Hoxa13/FAM3A axis regulating neuronal apoptosis in ischemic mice model.
Liu J, An P, Xue Y, Che D, Liu X, Zheng J, Liu Y, Yang C, Li Z, Yu B
Cell death & disease 2019 Jun 5;10(6):441
Cell death & disease 2019 Jun 5;10(6):441
ROS/JNK/c-Jun axis is involved in oridonin-induced caspase-dependent apoptosis in human colorectal cancer cells.
Zhang D, Zhou Q, Huang D, He L, Zhang H, Hu B, Peng H, Ren D
Biochemical and biophysical research communications 2019 Jun 4;513(3):594-601
Biochemical and biophysical research communications 2019 Jun 4;513(3):594-601
TGF-β mediates thoracic radiation-induced abscopal effects of testis injury in rat.
Zhang J, Yao D, Zhang J, Song Y, Mo F, Chu X, Pan Y, Bai Y, Shao C
Biochemical and biophysical research communications 2019 Jun 30;514(3):678-683
Biochemical and biophysical research communications 2019 Jun 30;514(3):678-683
Chitosan Hydrogel Delivery System Containing Herbal Compound Functions as a Potential Antineuroinflammatory Agent.
Zhou J, Zheng J, Zhang Y, Zheng P, Tang T, Luo JK, Cui HJ, Song RR, Wang Y
ACS omega 2019 Jun 30;4(6):10185-10191
ACS omega 2019 Jun 30;4(6):10185-10191
UHRF1 promotes aerobic glycolysis and proliferation via suppression of SIRT4 in pancreatic cancer.
Hu Q, Qin Y, Ji S, Xu W, Liu W, Sun Q, Zhang Z, Liu M, Ni Q, Yu X, Xu X
Cancer letters 2019 Jun 28;452:226-236
Cancer letters 2019 Jun 28;452:226-236
TRIP4 promotes tumor growth and metastasis and regulates radiosensitivity of cervical cancer by activating MAPK, PI3K/AKT, and hTERT signaling.
Che Y, Li Y, Zheng F, Zou K, Li Z, Chen M, Hu S, Tian C, Yu W, Guo W, Luo M, Deng W, Zou L
Cancer letters 2019 Jun 28;452:1-13
Cancer letters 2019 Jun 28;452:1-13
Silencing of Aberrant Secretory Protein Expression by Disease-Associated Mutations.
Tikhonova EB, Karamysheva ZN, von Heijne G, Karamyshev AL
Journal of molecular biology 2019 Jun 28;431(14):2567-2580
Journal of molecular biology 2019 Jun 28;431(14):2567-2580
Organophosphorus Flame Retardants Impair Intracellular Lipid Metabolic Function in Human Hepatocellular Cells.
Hao Z, Zhang Z, Lu D, Ding B, Shu L, Zhang Q, Wang C
Chemical research in toxicology 2019 Jun 17;32(6):1250-1258
Chemical research in toxicology 2019 Jun 17;32(6):1250-1258
Blocking podoplanin suppresses growth and pulmonary metastasis of human malignant melanoma.
Xu M, Wang X, Pan Y, Zhao X, Yan B, Ruan C, Xia L, Zhao Y
BMC cancer 2019 Jun 17;19(1):599
BMC cancer 2019 Jun 17;19(1):599
Insulin transcriptionally down-regulates carboxylesterases through pregnane X receptor in an Akt-dependent manner.
Yang X, Zhang X, Liu Y, Xi T, Xiong J
Toxicology 2019 Jun 15;422:60-68
Toxicology 2019 Jun 15;422:60-68
Inhibition of Glioma Development by ASCL1-Mediated Direct Neuronal Reprogramming.
Cheng X, Tan Z, Huang X, Yuan Y, Qin S, Gu Y, Wang D, He C, Su Z
Cells 2019 Jun 11;8(6)
Cells 2019 Jun 11;8(6)
Porcine HMGCR Inhibits Porcine Circovirus Type 2 Infection by Directly Interacting with the Viral Proteins.
Ouyang T, Niu G, Zhang Y, Liu X, Zhang X, Zhang S, Geng Y, Pang D, Ouyang H, Ren L
Viruses 2019 Jun 11;11(6)
Viruses 2019 Jun 11;11(6)
Sonodynamic therapy inhibits palmitate-induced beta cell dysfunction via PINK1/Parkin-dependent mitophagy.
Guo T, Liu T, Sun Y, Liu X, Xiong R, Li H, Li Z, Zhang Z, Tian Z, Tian Y
Cell death & disease 2019 Jun 11;10(6):457
Cell death & disease 2019 Jun 11;10(6):457
Macrophage Migration Inhibitory Factor Promotes Chemotaxis of Astrocytes through Regulation of Cholesterol 25-Hydroxylase Following Rat Spinal Cord Injury.
Zhu Z, Hu Y, Zhou Y, Zhang Y, Yu L, Tao L, Guo A, Fang Q
Neuroscience 2019 Jun 1;408:349-360
Neuroscience 2019 Jun 1;408:349-360
A new split-luciferase complementation assay identifies pentachlorophenol as an inhibitor of apoptosome formation.
Tashakor A, H-Dehkordi M, O'Connell E, Gomez Ganau S, Gozalbes R, Eriksson LA, Hosseinkhani S, Fearnhead HO
FEBS open bio 2019 Jul;9(7):1194-1203
FEBS open bio 2019 Jul;9(7):1194-1203
Activation of the immunoproteasome protects SH-SY5Y cells from the toxicity of rotenone.
Sun C, Mo M, Wang Y, Yu W, Song C, Wang X, Chen S, Liu Y
Neurotoxicology 2019 Jul;73:112-119
Neurotoxicology 2019 Jul;73:112-119
Atractylodin ameliorates lipopolysaccharide and d-galactosamine-induced acute liver failure via the suppression of inflammation and oxidative stress.
Lyu Z, Ji X, Chen G, An B
International immunopharmacology 2019 Jul;72:348-357
International immunopharmacology 2019 Jul;72:348-357
MicroRNA-221 sensitizes chronic myeloid leukemia cells to imatinib by targeting STAT5.
Jiang X, Cheng Y, Hu C, Zhang A, Ren Y, Xu X
Leukemia & lymphoma 2019 Jul;60(7):1709-1720
Leukemia & lymphoma 2019 Jul;60(7):1709-1720
Epithelial ovarian cancer stem‑like cells are resistant to the cellular lysis of cytokine‑induced killer cells via HIF1A‑mediated downregulation of ICAM‑1.
Bu S, Li B, Wang Q, Gu T, Dong Q, Miao X, Lai D
International journal of oncology 2019 Jul;55(1):179-190
International journal of oncology 2019 Jul;55(1):179-190
Aspirin targets P4HA2 through inhibiting NF-κB and LMCD1-AS1/let-7g to inhibit tumour growth and collagen deposition in hepatocellular carcinoma.
Wang T, Fu X, Jin T, Zhang L, Liu B, Wu Y, Xu F, Wang X, Ye K, Zhang W, Ye L
EBioMedicine 2019 Jul;45:168-180
EBioMedicine 2019 Jul;45:168-180
Tubeimoside-1, a triterpenoid saponin, induces cytoprotective autophagy in human breast cancer cells in vitro via Akt-mediated pathway.
Jiang SL, Guan YD, Chen XS, Ge P, Wang XL, Lao YZ, Xiao SS, Zhang Y, Yang JM, Xu XJ, Cao DS, Cheng Y
Acta pharmacologica Sinica 2019 Jul;40(7):919-928
Acta pharmacologica Sinica 2019 Jul;40(7):919-928
Septin 9 isoforms promote tumorigenesis in mammary epithelial cells by increasing migration and ECM degradation through metalloproteinase secretion at focal adhesions.
Marcus J, Bejerano-Sagie M, Patterson N, Bagchi S, Verkhusha VV, Connolly D, Goldberg GL, Golden A, Sharma VP, Condeelis J, Montagna C
Oncogene 2019 Jul;38(30):5839-5859
Oncogene 2019 Jul;38(30):5839-5859
STAT3 phosphorylation mediates high glucose-impaired cell autophagy in an HDAC1-dependent and -independent manner in Schwann cells of diabetic peripheral neuropathy.
Du W, Wang N, Li F, Jia K, An J, Liu Y, Wang Y, Zhu L, Zhao S, Hao J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jul;33(7):8008-8021
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jul;33(7):8008-8021
Notch signaling activation induces cell death in MAPKi-resistant melanoma cells.
Mikheil DM, Prabhakar K, Arshad A, Rodriguez CI, Newton MA, Setaluri V
Pigment cell & melanoma research 2019 Jul;32(4):528-539
Pigment cell & melanoma research 2019 Jul;32(4):528-539
Complement C3 activation regulates the production of tRNA-derived fragments Gly-tRFs and promotes alcohol-induced liver injury and steatosis.
Zhong F, Hu Z, Jiang K, Lei B, Wu Z, Yuan G, Luo H, Dong C, Tang B, Zheng C, Yang S, Zeng Y, Guo Z, Yu S, Su H, Zhang G, Qiu X, Tomlinson S, He S
Cell research 2019 Jul;29(7):548-561
Cell research 2019 Jul;29(7):548-561
CtIP promotes G2/M arrest in etoposide-treated HCT116 cells in a p53-independent manner.
Chen H, Shan J, Chen D, Wang R, Qi W, Wang H, Ke Y, Liu W, Zeng X
Journal of cellular physiology 2019 Jul;234(7):11871-11881
Journal of cellular physiology 2019 Jul;234(7):11871-11881
DAAM1-mediated migration and invasion of ovarian cancer cells are suppressed by miR-208a-5p.
Mei J, Huang Y, Hao L, Liu Y, Yan T, Qiu T, Xu R, Xu B, Xiao Z, Jiang X, Hu K, Zhu Y
Pathology, research and practice 2019 Jul;215(7):152452
Pathology, research and practice 2019 Jul;215(7):152452
CDK1 and CDK2 regulate NICD1 turnover and the periodicity of the segmentation clock.
Carrieri FA, Murray PJ, Ditsova D, Ferris MA, Davies P, Dale JK
EMBO reports 2019 Jul;20(7):e46436
EMBO reports 2019 Jul;20(7):e46436
Harnessing the anti-cancer natural product nimbolide for targeted protein degradation.
Spradlin JN, Hu X, Ward CC, Brittain SM, Jones MD, Ou L, To M, Proudfoot A, Ornelas E, Woldegiorgis M, Olzmann JA, Bussiere DE, Thomas JR, Tallarico JA, McKenna JM, Schirle M, Maimone TJ, Nomura DK
Nature chemical biology 2019 Jul;15(7):747-755
Nature chemical biology 2019 Jul;15(7):747-755
Observation of novel COX20 mutations related to autosomal recessive axonal neuropathy and static encephalopathy.
Xu H, Ji T, Lian Y, Wang S, Chen X, Li S, Yin Y, Dong X
Human genetics 2019 Jul;138(7):749-756
Human genetics 2019 Jul;138(7):749-756
Low-dose PCB126 compromises circadian rhythms associated with disordered glucose and lipid metabolism in mice.
Shen X, Chen Y, Zhang J, Yan X, Liu W, Guo Y, Shan Q, Liu S
Environment international 2019 Jul;128:146-157
Environment international 2019 Jul;128:146-157
UCP2 alleviates tubular epithelial cell apoptosis in lipopolysaccharide-induced acute kidney injury by decreasing ROS production.
Zhong X, He J, Zhang X, Li C, Tian X, Xia W, Gan H, Xia Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108914
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108914
Roscovitine attenuates renal interstitial fibrosis in diabetic mice through the TGF-β1/p38 MAPK pathway.
Wang S, Zhou Y, Zhang Y, He X, Zhao X, Zhao H, Liu W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108895
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108895
Naringenin ameliorates insulin resistance by modulating endoplasmic reticulum stress in hepatitis C virus-infected liver.
Jia B, Wang Y, Yu G, Cheng Y, Yang C, Cao F, He Y, Cao P, Meng X, Yu D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108848
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108848
Regulation of CD11b by HIF-1α and the STAT3 signaling pathway contributes to the immunosuppressive function of B cells in inflammatory bowel disease.
Qian T, Hong J, Wang L, Wang Z, Lu Z, Li Y, Liu R, Chu Y
Molecular immunology 2019 Jul;111:162-171
Molecular immunology 2019 Jul;111:162-171
Lysine glutarylation in human sperm is associated with progressive motility.
Cheng YM, Hu XN, Peng Z, Pan TT, Wang F, Chen HY, Chen WQ, Zhang Y, Zeng XH, Luo T
Human reproduction (Oxford, England) 2019 Jul 8;34(7):1186-1194
Human reproduction (Oxford, England) 2019 Jul 8;34(7):1186-1194
Inhibition of nucleotide synthesis promotes replicative senescence of human mammary epithelial cells.
Delfarah A, Parrish S, Junge JA, Yang J, Seo F, Li S, Mac J, Wang P, Fraser SE, Graham NA
The Journal of biological chemistry 2019 Jul 5;294(27):10564-10578
The Journal of biological chemistry 2019 Jul 5;294(27):10564-10578
A novel hydrogen sulfide-releasing donor, HA-ADT, suppresses the growth of human breast cancer cells through inhibiting the PI3K/AKT/mTOR and Ras/Raf/MEK/ERK signaling pathways.
Dong Q, Yang B, Han JG, Zhang MM, Liu W, Zhang X, Yu HL, Liu ZG, Zhang SH, Li T, Wu DD, Ji XY, Duan SF
Cancer letters 2019 Jul 28;455:60-72
Cancer letters 2019 Jul 28;455:60-72
Lingguizhugan decoction attenuates diet-induced obesity and hepatosteatosis via gut microbiota.
Liu MT, Huang YJ, Zhang TY, Tan LB, Lu XF, Qin J
World journal of gastroenterology 2019 Jul 21;25(27):3590-3606
World journal of gastroenterology 2019 Jul 21;25(27):3590-3606
Hypoxia inducible factor 1α in vascular smooth muscle cells promotes angiotensin II-induced vascular remodeling via activation of CCL7-mediated macrophage recruitment.
Qi D, Wei M, Jiao S, Song Y, Wang X, Xie G, Taranto J, Liu Y, Duan Y, Yu B, Li H, Shah YM, Xu Q, Du J, Gonzalez FJ, Qu A
Cell death & disease 2019 Jul 18;10(8):544
Cell death & disease 2019 Jul 18;10(8):544
AcMNPV PKIP is associated with nucleocapsid of budded virions and involved in nucleocapsid assembly.
Lai Q, Zhu L, Xu L, Yuan M, Wu W, Yang K
Virus research 2019 Jul 15;268:27-37
Virus research 2019 Jul 15;268:27-37
CUL7 E3 Ubiquitin Ligase Mediates the Degradation of Activation-Induced Cytidine Deaminase and Regulates the Ig Class Switch Recombination in B Lymphocytes.
Luo Y, Liu Y, Wu L, Ma X, Liu Q, Huang F, Zhang X, Zhang Y, Zhang J, Luo H, Yang Y, Lu G, Tang X, Li L, Zeng Y, Pan T, Zhang H
Journal of immunology (Baltimore, Md. : 1950) 2019 Jul 1;203(1):269-281
Journal of immunology (Baltimore, Md. : 1950) 2019 Jul 1;203(1):269-281
Tri-ortho-cresyl phosphate (TOCP) induced ovarian failure in mice is related to the Hippo signaling pathway disruption.
Hu L, Peng T, Huang J, Su T, Luo R, Zheng Y, Zhong Z, Yu P, Nie K, Zheng L
Reproductive toxicology (Elmsford, N.Y.) 2019 Jan;83:21-27
Reproductive toxicology (Elmsford, N.Y.) 2019 Jan;83:21-27
Autocrine secretions enhance radioresistance in an exosome‑independent manner in NSCLC cells.
Wang S, Gao P, Li N, Chen P, Wang J, He N, Ji K, Du L, Liu Q
International journal of oncology 2019 Jan;54(1):229-238
International journal of oncology 2019 Jan;54(1):229-238
miR-132-3p boosts caveolae-mediated transcellular transport in glioma endothelial cells by targeting PTEN/PI3K/PKB/Src/Cav-1 signaling pathway.
Gu Y, Cai R, Zhang C, Xue Y, Pan Y, Wang J, Zhang Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jan;33(1):441-454
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jan;33(1):441-454
Plant-derived alkaloid sinomenine potentiates glucocorticoid pharmacodynamics in mitogen-activated human peripheral blood mononuclear cells by regulating the translocation of glucocorticoid receptor.
Xu W, Wang X, Tu Y, Masaki H, Tanaka S, Onda K, Sugiyama K, Yamada H, Hirano T
Phytotherapy research : PTR 2019 Jan;33(1):187-196
Phytotherapy research : PTR 2019 Jan;33(1):187-196
MMP-9 Upregulation is Attenuated by the Monoclonal TLR2 Antagonist T2.5 After Oxygen-Glucose Deprivation and Reoxygenation in Rat Brain Microvascular Endothelial Cells.
Zhu H, Dai R, Fu H, Meng Q
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2019 Jan;28(1):97-106
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2019 Jan;28(1):97-106
Function of BRD4 in the pathogenesis of high glucose‑induced cardiac hypertrophy.
Wang Q, Sun Y, Li T, Liu L, Zhao Y, Li L, Zhang L, Meng Y
Molecular medicine reports 2019 Jan;19(1):499-507
Molecular medicine reports 2019 Jan;19(1):499-507
SVIP alleviates CCl(4)-induced liver fibrosis via activating autophagy and protecting hepatocytes.
Jia D, Wang YY, Wang P, Huang Y, Liang DY, Wang D, Cheng C, Zhang C, Guo L, Liang P, Wang Y, Jia Y, Li C
Cell death & disease 2019 Jan 25;10(2):71
Cell death & disease 2019 Jan 25;10(2):71
LncRNA SNHG12 inhibits miR-199a to upregulate SIRT1 to attenuate cerebral ischemia/reperfusion injury through activating AMPK signaling pathway.
Yin WL, Yin WG, Huang BS, Wu LX
Neuroscience letters 2019 Jan 18;690:188-195
Neuroscience letters 2019 Jan 18;690:188-195
Reciprocal regulation of integrin β4 and KLF4 promotes gliomagenesis through maintaining cancer stem cell traits.
Ma B, Zhang L, Zou Y, He R, Wu Q, Han C, Zhang B
Journal of experimental & clinical cancer research : CR 2019 Jan 18;38(1):23
Journal of experimental & clinical cancer research : CR 2019 Jan 18;38(1):23
MMP13 inhibition rescues cognitive decline in Alzheimer transgenic mice via BACE1 regulation.
Zhu BL, Long Y, Luo W, Yan Z, Lai YJ, Zhao LG, Zhou WH, Wang YJ, Shen LL, Liu L, Deng XJ, Wang XF, Sun F, Chen GJ
Brain : a journal of neurology 2019 Jan 1;142(1):176-192
Brain : a journal of neurology 2019 Jan 1;142(1):176-192
Mechanism underlying the retarded nuclear translocation of androgen receptor splice variants.
Liu Y, Wang Y, Wang F, Pan J, Xu J, Li J, Zhou C, Ding G, Wu Y, Liu X, Sheng J, Huang H
Science China. Life sciences 2019 Feb;62(2):257-267
Science China. Life sciences 2019 Feb;62(2):257-267
Sodium rutin ameliorates Alzheimer's disease-like pathology by enhancing microglial amyloid-β clearance.
Pan RY, Ma J, Kong XX, Wang XF, Li SS, Qi XL, Yan YH, Cheng J, Liu Q, Jin W, Tan CH, Yuan Z
Science advances 2019 Feb;5(2):eaau6328
Science advances 2019 Feb;5(2):eaau6328
Nucleoporin 107 facilitates the nuclear export of Scn5a mRNA to regulate cardiac bioelectricity.
Guan Y, Gao X, Tang Q, Huang L, Gao S, Yu S, Huang J, Li J, Zhou D, Zhang Y, Shi D, Liang D, Liu Y, Li L, Cui Y, Xu L, Chen YH
Journal of cellular and molecular medicine 2019 Feb;23(2):1448-1457
Journal of cellular and molecular medicine 2019 Feb;23(2):1448-1457
Effects of Fluoride on Autophagy in Mouse Sertoli Cells.
Feng Z, Liang C, Manthari RK, Wang C, Zhang J
Biological trace element research 2019 Feb;187(2):499-505
Biological trace element research 2019 Feb;187(2):499-505
CDK11(p110) plays a critical role in the tumorigenicity of esophageal squamous cell carcinoma cells and is a potential drug target.
Du Y, Yan D, Yuan Y, Xu J, Wang S, Yang Z, Cheng W, Tian X, Kan Q
Cell cycle (Georgetown, Tex.) 2019 Feb;18(4):452-466
Cell cycle (Georgetown, Tex.) 2019 Feb;18(4):452-466
Berberrubine and its analog, hydroxypropyl-berberrubine, regulate LDLR and PCSK9 expression via the ERK signal pathway to exert cholesterol-lowering effects in human hepatoma HepG2 cells.
Cao S, Xu P, Yan J, Liu H, Liu L, Cheng L, Qiu F, Kang N
Journal of cellular biochemistry 2019 Feb;120(2):1340-1349
Journal of cellular biochemistry 2019 Feb;120(2):1340-1349
Intestinal non-canonical NFκB signaling shapes the local and systemic immune response.
Ramakrishnan SK, Zhang H, Ma X, Jung I, Schwartz AJ, Triner D, Devenport SN, Das NK, Xue X, Zeng MY, Hu Y, Mortensen RM, Greenson JK, Cascalho M, Wobus CE, Colacino JA, Nunez G, Rui L, Shah YM
Nature communications 2019 Feb 8;10(1):660
Nature communications 2019 Feb 8;10(1):660
Dietary canolol induces apoptosis in human cervical carcinoma HeLa cells through ROS-MAPK mediated mitochondrial signaling pathway: In vitro and in vivo.
Xia X, Xiang X, Huang F, Zheng M, Zhang Z, Han L
Chemico-biological interactions 2019 Feb 25;300:138-150
Chemico-biological interactions 2019 Feb 25;300:138-150
Regulation of macrophage iron homeostasis is associated with the localization of bacteria.
Gan Z, Tang X, Wang Z, Li J, Wang Z, Du H
Metallomics : integrated biometal science 2019 Feb 20;11(2):454-461
Metallomics : integrated biometal science 2019 Feb 20;11(2):454-461
Kibra Modulates Learning and Memory via Binding to Dendrin.
Ji Z, Li H, Yang Z, Huang X, Ke X, Ma S, Lin Z, Lu Y, Zhang M
Cell reports 2019 Feb 19;26(8):2064-2077.e7
Cell reports 2019 Feb 19;26(8):2064-2077.e7
miR-33 and RIP140 participate in LPS-induced acute lung injury.
Li H, Hou H, Liu S, Feng Y, Zhong W, Hu X, Yan N
Turkish journal of medical sciences 2019 Feb 11;49(1):422-428
Turkish journal of medical sciences 2019 Feb 11;49(1):422-428
Gene expression profile-based drug screen identifies SAHA as a novel treatment for NAFLD.
Cheng Z, Wen Y, Liang B, Chen S, Liu Y, Wang Z, Cheng J, Tang X, Xin H, Deng L
Molecular omics 2019 Feb 11;15(1):50-58
Molecular omics 2019 Feb 11;15(1):50-58
The Autographa californica Multiple Nucleopolyhedrovirus ac51 Gene Is Required for Efficient Nuclear Egress of Nucleocapsids and Is Essential for In Vivo Virulence.
Qiu J, Tang Z, Cai Y, Wu W, Yuan M, Yang K
Journal of virology 2019 Feb 1;93(3)
Journal of virology 2019 Feb 1;93(3)
SRT1720 retards renal fibrosis via inhibition of HIF1α /GLUT1 in diabetic nephropathy.
Han W, Wang C, Yang Z, Mu L, Wu M, Chen N, Du C, Duan H, Shi Y
The Journal of endocrinology 2019 Feb 1;
The Journal of endocrinology 2019 Feb 1;
JAK2/STAT1-mediated HMGB1 translocation increases inflammation and cell death in a ventilator-induced lung injury model.
Liu Q, Xie W, Wang Y, Chen S, Han J, Wang L, Gui P, Wu Q
Laboratory investigation; a journal of technical methods and pathology 2019 Dec;99(12):1810-1821
Laboratory investigation; a journal of technical methods and pathology 2019 Dec;99(12):1810-1821
LncRNA SNHG4 promotes the proliferation, migration, invasiveness, and epithelial-mesenchymal transition of lung cancer cells by regulating miR-98-5p.
Tang Y, Wu L, Zhao M, Zhao G, Mao S, Wang L, Liu S, Wang X
Biochemistry and cell biology = Biochimie et biologie cellulaire 2019 Dec;97(6):767-776
Biochemistry and cell biology = Biochimie et biologie cellulaire 2019 Dec;97(6):767-776
NO donor inhibits proliferation and induces apoptosis by targeting PI3K/AKT/mTOR and MEK/ERK pathways in hepatocellular carcinoma cells.
Liu L, Chen J, Cao M, Wang J, Wang S
Cancer chemotherapy and pharmacology 2019 Dec;84(6):1303-1314
Cancer chemotherapy and pharmacology 2019 Dec;84(6):1303-1314
Carpesium abrotanoides (L.) Root as a Potential Source of Natural Anticancer Compounds: Targeting Glucose Metabolism and PKM2/HIF-1α Axis of Breast Cancer Cells.
Chai XX, Le YF, Wang JC, Mei CX, Feng JF, Zhao H, Wang C, Lu DZ
Journal of food science 2019 Dec;84(12):3825-3832
Journal of food science 2019 Dec;84(12):3825-3832
Indoxyl sulfate-induced calcification of vascular smooth muscle cells via the PI3K/Akt/NF-κB signaling pathway.
He X, Jiang H, Gao F, Liang S, Wei M, Chen L
Microscopy research and technique 2019 Dec;82(12):2000-2006
Microscopy research and technique 2019 Dec;82(12):2000-2006
Peroxisome Proliferator-Activated Receptors (PPARs) levels in spermatozoa of normozoospermic and asthenozoospermic men.
Mousavi MS, Shahverdi A, Drevet J, Akbarinejad V, Esmaeili V, Sayahpour FA, Topraggaleh TR, Rahimizadeh P, Alizadeh A
Systems biology in reproductive medicine 2019 Dec;65(6):409-419
Systems biology in reproductive medicine 2019 Dec;65(6):409-419
LncRNA-241 inhibits 1,2-Dichloroethane-induced hepatic apoptosis.
Zeng N, Zhang Z, Jiang H, Li R, Chang C, Wang F, Xu D, Fan Q, Wang T, Xiao Y, Chen W, Shan Z, Huang Z, Wang Q
Toxicology in vitro : an international journal published in association with BIBRA 2019 Dec;61:104650
Toxicology in vitro : an international journal published in association with BIBRA 2019 Dec;61:104650
Lipopolysaccharide-induced DNA damage response activates nuclear factor κB signalling pathway via GATA4 in dental pulp cells.
Qiao W, Huang Y, Bian Z, Sun X, Wang X, Gao Q, Peng Y, Meng L
International endodontic journal 2019 Dec;52(12):1704-1715
International endodontic journal 2019 Dec;52(12):1704-1715
Transcriptome sequencing of Eospalax fontanierii to determine hypoxia regulation of cardiac fibrinogen.
Xu L, Hao Z, Lin J, Zhao Q, Zhang B, Li G, He J, Li J
Molecular biology reports 2019 Dec;46(6):5671-5683
Molecular biology reports 2019 Dec;46(6):5671-5683
Dysregulated Transcription Factor TFAP2A After Peripheral Nerve Injury Modulated Schwann Cell Phenotype.
Zhang F, Gu X, Yi S, Xu H
Neurochemical research 2019 Dec;44(12):2776-2785
Neurochemical research 2019 Dec;44(12):2776-2785
ORP4L couples IP(3) to ITPR1 in control of endoplasmic reticulum calcium release.
Cao X, Chen J, Li D, Xie P, Xu M, Lin W, Li S, Pan G, Tang Y, Xu J, Olkkonen VM, Yan D, Zhong W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Dec;33(12):13852-13865
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Dec;33(12):13852-13865
Base pair editing in goat: nonsense codon introgression into FGF5 results in longer hair.
Li G, Zhou S, Li C, Cai B, Yu H, Ma B, Huang Y, Ding Y, Liu Y, Ding Q, He C, Zhou J, Wang Y, Zhou G, Li Y, Yan Y, Hua J, Petersen B, Jiang Y, Sonstegard T, Huang X, Chen Y, Wang X
The FEBS journal 2019 Dec;286(23):4675-4692
The FEBS journal 2019 Dec;286(23):4675-4692
Rotenone protects against β-cell apoptosis and attenuates type 1 diabetes mellitus.
Wu M, Chen W, Zhang S, Huang S, Zhang A, Zhang Y, Jia Z
Apoptosis : an international journal on programmed cell death 2019 Dec;24(11-12):879-891
Apoptosis : an international journal on programmed cell death 2019 Dec;24(11-12):879-891
S100A9 regulates porcine reproductive and respiratory syndrome virus replication by interacting with the viral nucleocapsid protein.
Song Z, Bai J, Liu X, Nauwynck H, Wu J, Liu X, Jiang P
Veterinary microbiology 2019 Dec;239:108498
Veterinary microbiology 2019 Dec;239:108498
Tandem repeat sequence of duck circovirus serves as downstream sequence element to regulate viral gene expression.
Wu ZC, Xia XJ, Li HR, Jiang SJ, Ma ZY, Wang X
Veterinary microbiology 2019 Dec;239:108496
Veterinary microbiology 2019 Dec;239:108496
MicroRNA-181b-5p modulates tumor necrosis factor-α-induced inflammatory responses by targeting interleukin-6 in cementoblasts.
Wang X, Sun H, Liu H, Ma L, Jiang C, Liao H, Xu S, Xiang J, Cao Z
Journal of cellular physiology 2019 Dec;234(12):22719-22730
Journal of cellular physiology 2019 Dec;234(12):22719-22730
Role of nuclear factor-κB pathway in the transition of mouse secondary follicles to antral follicles.
Xu JJ, Wang G, Luo X, Wang LJ, Bao Y, Yang X
Journal of cellular physiology 2019 Dec;234(12):22565-22580
Journal of cellular physiology 2019 Dec;234(12):22565-22580
miR-451a inhibits cancer growth, epithelial-mesenchymal transition and induces apoptosis in papillary thyroid cancer by targeting PSMB8.
Fan X, Zhao Y
Journal of cellular and molecular medicine 2019 Dec;23(12):8067-8075
Journal of cellular and molecular medicine 2019 Dec;23(12):8067-8075
Punicalagin Reversed the Hepatic Injury of Tetrachloromethane by Antioxidation and Enhancement of Autophagy.
Luo J, Long Y, Ren G, Zhang Y, Chen J, Huang R, Yang L
Journal of medicinal food 2019 Dec;22(12):1271-1279
Journal of medicinal food 2019 Dec;22(12):1271-1279
Hypoxia enhances IL-10-producing B cell generation through upregulating high-mobility group B1 on tumor cell-released autophagosomes.
Zhang Y, Pan N, Sheng Y, Zhou M, Wen Z, Chen Y, Huang F, Wang LX
Immunology letters 2019 Dec;216:36-42
Immunology letters 2019 Dec;216:36-42
Novel sphingomyelin biomarkers for brain glioma and associated regulation research on the PI3K/Akt signaling pathway.
Zhai XH, Xiao J, Yu JK, Sun H, Zheng S
Oncology letters 2019 Dec;18(6):6207-6213
Oncology letters 2019 Dec;18(6):6207-6213
Catalpol alleviates adriamycin-induced nephropathy by activating the SIRT1 signalling pathway in vivo and in vitro.
Zhang J, Bi R, Meng Q, Wang C, Huo X, Liu Z, Wang C, Sun P, Sun H, Ma X, Wu J, Liu K
British journal of pharmacology 2019 Dec;176(23):4558-4573
British journal of pharmacology 2019 Dec;176(23):4558-4573
HDAC11 restricts HBV replication through epigenetic repression of cccDNA transcription.
Yuan Y, Zhao K, Yao Y, Liu C, Chen Y, Li J, Wang Y, Pei R, Chen J, Hu X, Zhou Y, Wu C, Chen X
Antiviral research 2019 Dec;172:104619
Antiviral research 2019 Dec;172:104619
BECN1 promotes the migration of NSCLC cells through regulating the ubiquitination of Vimentin.
Cheng Z, Xin H, Han T
Cell adhesion & migration 2019 Dec;13(1):249-259
Cell adhesion & migration 2019 Dec;13(1):249-259
Xiaoerfupi alleviates the symptoms of functional dyspepsia by regulating the HTR3A and c-FOS.
Ji E, Wang T, Guo F, Zhang Y, Tang C, Tang D, Wei J, Yang H, Xian M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109442
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109442
Pleiotropic Effects of Epithelial Mesenchymal Crosstalk on Head and Neck Cancer: EMT and beyond.
Steinbichler TB, Savic D, Dejaco D, Romani A, Kofler B, Skvortsova II, Riechelmann H, Dudas J
Cancer microenvironment : official journal of the International Cancer Microenvironment Society 2019 Dec;12(2-3):67-76
Cancer microenvironment : official journal of the International Cancer Microenvironment Society 2019 Dec;12(2-3):67-76
Endocytic degradation of ErbB2 mediates the effectiveness of neratinib in the suppression of ErbB2-positive ovarian cancer.
Wang S, Zhang J, Wang T, Ren F, Liu X, Lu Y, Xu L, Zhang Y, Wang D, Xu L, Wu Y, Liu F, Li Q, Zaky MY, Liu S, Dong W, Liu F, Zou K, Zhang Y
The international journal of biochemistry & cell biology 2019 Dec;117:105640
The international journal of biochemistry & cell biology 2019 Dec;117:105640
Curcumin inhibits LPS-induced neuroinflammation by promoting microglial M2 polarization via TREM2/ TLR4/ NF-κB pathways in BV2 cells.
Zhang J, Zheng Y, Luo Y, Du Y, Zhang X, Fu J
Molecular immunology 2019 Dec;116:29-37
Molecular immunology 2019 Dec;116:29-37
Critical roles of NLRP3 inflammasome in IL-1β secretion induced by Corynebacterium pseudotuberculosis in vitro.
Zhou Z, Li H, Tian S, Yi W, Zhou Y, Yang H, Li X, Wu B, Li X, Wu J, Wang Z, Hu S, Fang R
Molecular immunology 2019 Dec;116:11-17
Molecular immunology 2019 Dec;116:11-17
Activating macrophages for enhanced osteogenic and bactericidal performance by Cu ion release from micro/nano-topographical coating on a titanium substrate.
Huang Q, Ouyang Z, Tan Y, Wu H, Liu Y
Acta biomaterialia 2019 Dec;100:415-426
Acta biomaterialia 2019 Dec;100:415-426
Oral Administration of Succinoglycan Riclin Improves Diet-Induced Hypercholesterolemia in Mice.
Yang Y, Sun Q, Xu X, Yang X, Gao Y, Sun X, Zhao Y, Ding Z, Ge W, Cheng R, Zhang J
Journal of agricultural and food chemistry 2019 Dec 4;67(48):13307-13317
Journal of agricultural and food chemistry 2019 Dec 4;67(48):13307-13317
Yes-associated protein regulates podocyte cell cycle re-entry and dedifferentiation in adriamycin-induced nephropathy.
Xie K, Xu C, Zhang M, Wang M, Min L, Qian C, Wang Q, Ni Z, Mou S, Dai H, Pang H, Gu L
Cell death & disease 2019 Dec 4;10(12):915
Cell death & disease 2019 Dec 4;10(12):915
Sal B Alleviates Myocardial Ischemic Injury by Inhibiting TLR4 and the Priming Phase of NLRP3 Inflammasome.
Hu Y, Li Q, Pan Y, Xu L
Molecules (Basel, Switzerland) 2019 Dec 3;24(23)
Molecules (Basel, Switzerland) 2019 Dec 3;24(23)
Hydrogen sulfide attenuates mitochondrial dysfunction-induced cellular senescence and apoptosis in alveolar epithelial cells by upregulating sirtuin 1.
Guan R, Cai Z, Wang J, Ding M, Li Z, Xu J, Li Y, Li J, Yao H, Liu W, Qian J, Deng B, Tang C, Sun D, Lu W
Aging 2019 Dec 23;11(24):11844-11864
Aging 2019 Dec 23;11(24):11844-11864
Beneficial Effects of Ticagrelor on Oxidized Low-Density Lipoprotein (ox-LDL)-Induced Apoptosis in Human Umbilical Vein Endothelial Cells.
Kang M, Shao S, Zhang Y, Liang X, Zhang K, Li G
Medical science monitor : international medical journal of experimental and clinical research 2019 Dec 21;25:9811-9819
Medical science monitor : international medical journal of experimental and clinical research 2019 Dec 21;25:9811-9819
RASAL1 induces to downregulate the SCD1, leading to suppression of cell proliferation in colon cancer via LXRα/SREBP1c pathway.
Wang G, Li Z, Li X, Zhang C, Peng L
Biological research 2019 Dec 17;52(1):60
Biological research 2019 Dec 17;52(1):60
Stasimon Contributes to the Loss of Sensory Synapses and Motor Neuron Death in a Mouse Model of Spinal Muscular Atrophy.
Simon CM, Van Alstyne M, Lotti F, Bianchetti E, Tisdale S, Watterson DM, Mentis GZ, Pellizzoni L
Cell reports 2019 Dec 17;29(12):3885-3901.e5
Cell reports 2019 Dec 17;29(12):3885-3901.e5
Gdf11 gene transfer prevents high fat diet-induced obesity and improves metabolic homeostasis in obese and STZ-induced diabetic mice.
Lu B, Zhong J, Pan J, Yuan X, Ren M, Jiang L, Yang Y, Zhang G, Liu D, Zhang C
Journal of translational medicine 2019 Dec 17;17(1):422
Journal of translational medicine 2019 Dec 17;17(1):422
Integration of transcriptomics and network analysis deciphers the mechanisms of baicalein in improving learning and memory impairment in senescence-accelerated mouse prone 8 (SAMP8).
Li J, Zhou Y, Du G, Qin X, Gao L
European journal of pharmacology 2019 Dec 15;865:172789
European journal of pharmacology 2019 Dec 15;865:172789
Rafoxanide promotes apoptosis and autophagy of gastric cancer cells by suppressing PI3K /Akt/mTOR pathway.
Liu JZ, Hu YL, Feng Y, Guo YB, Liu YF, Yang JL, Mao QS, Xue WJ
Experimental cell research 2019 Dec 15;385(2):111691
Experimental cell research 2019 Dec 15;385(2):111691
PI3K/Akt inhibitor partly decreases TNF-α-induced activation of fibroblast-like synoviocytes in osteoarthritis.
Liu S, Cao C, Zhang Y, Liu G, Ren W, Ye Y, Sun T
Journal of orthopaedic surgery and research 2019 Dec 11;14(1):425
Journal of orthopaedic surgery and research 2019 Dec 11;14(1):425
Aptamer-Based Erythrocyte-Derived Mimic Vesicles Loaded with siRNA and Doxorubicin for the Targeted Treatment of Multidrug-Resistant Tumors.
Wang T, Luo Y, Lv H, Wang J, Zhang Y, Pei R
ACS applied materials & interfaces 2019 Dec 11;11(49):45455-45466
ACS applied materials & interfaces 2019 Dec 11;11(49):45455-45466
7-O-geranylquercetin contributes to reverse P-gp-mediated adriamycin resistance in breast cancer.
Zhang E, Liu J, Shi L, Guo X, Liang Z, Zuo J, Xu H, Wang H, Shu X, Huang S, Zhang S, Kang X, Zhen Y
Life sciences 2019 Dec 1;238:116938
Life sciences 2019 Dec 1;238:116938
Fe(3)O(4)@OA@Poloxamer nanoparticles lower triglyceride in hepatocytes through liposuction effect and nano-enzyme effect.
Sun Y, Shi F, Niu Y, Zhang Y, Xiong F
Colloids and surfaces. B, Biointerfaces 2019 Dec 1;184:110528
Colloids and surfaces. B, Biointerfaces 2019 Dec 1;184:110528
Abnormal expression of Pappa2 gene may indirectly affect mouse hip development through the IGF signaling pathway.
Chen Y, Li L, Wang E, Zhang L, Zhao Q
Endocrine 2019 Aug;65(2):440-450
Endocrine 2019 Aug;65(2):440-450
MIF/CD74 axis participates in inflammatory activation of Schwann cells following sciatic nerve injury.
Song H, Zhu Z, Zhou Y, Du N, Song T, Liang H, Chen X, Wang Y, Wang Y, Hu Y
Journal of molecular histology 2019 Aug;50(4):355-367
Journal of molecular histology 2019 Aug;50(4):355-367
In Vitro Infectious Risk Assessment of Heliothis virescens ascovirus 3j (HvAV-3j) toward Non-target Vertebrate Cells.
Yu H, Ou-Yang YY, Li N, Nakai M, Huang GH
Virologica Sinica 2019 Aug;34(4):423-433
Virologica Sinica 2019 Aug;34(4):423-433
PLZF regulates apoptosis of leukemia cells by regulating AKT/Foxo3a pathway.
Li JX, Zhang ZF, Wang XB, Yang EQ, Dong L, Meng J
European review for medical and pharmacological sciences 2019 Aug;23(15):6411-6418
European review for medical and pharmacological sciences 2019 Aug;23(15):6411-6418
The effects of fluorene-9-bisphenol on female zebrafish (Danio rerio) reproductive and exploratory behaviors.
Mi P, Zhang QP, Zhang SH, Wang C, Zhang SZ, Fang YC, Gao JZ, Feng DF, Chen DY, Feng XZ
Chemosphere 2019 Aug;228:398-411
Chemosphere 2019 Aug;228:398-411
17β‑Estradiol protects against interleukin‑1β‑induced apoptosis in rat nucleus pulposus cells via the mTOR/caspase‑3 pathway.
Guo HT, Yang SD, Zhang F, Liu S, Yang DL, Ma L, Wang H, Ding WY
Molecular medicine reports 2019 Aug;20(2):1523-1530
Molecular medicine reports 2019 Aug;20(2):1523-1530
Proteomic Analysis Reveals that Odoroside A Triggers G2/M Arrest and Apoptosis in Colorectal Carcinoma Through ROS-p53 Pathway.
Chen YY, Wen SY, Deng CM, Yin XF, Sun ZH, Jiang MM, He QY
Proteomics 2019 Aug;19(15):e1900092
Proteomics 2019 Aug;19(15):e1900092
Diosgenin regulates cholesterol metabolism in hypercholesterolemic rats by inhibiting NPC1L1 and enhancing ABCG5 and ABCG8.
Li R, Liu Y, Shi J, Yu Y, Lu H, Yu L, Liu Y, Zhang F
Biochimica et biophysica acta. Molecular and cell biology of lipids 2019 Aug;1864(8):1124-1133
Biochimica et biophysica acta. Molecular and cell biology of lipids 2019 Aug;1864(8):1124-1133
HSF1 phosphorylation by cyclosporin A confers hyperthermia sensitivity through suppression of HSP expression.
Shao J, Han B, Cao P, Zhang B, Liu M, Li D, Zhou N, Hao Q, Duan X, Chang Y, Nakai A, Fan Y, Tan K
Biochimica et biophysica acta. Gene regulatory mechanisms 2019 Aug;1862(8):846-857
Biochimica et biophysica acta. Gene regulatory mechanisms 2019 Aug;1862(8):846-857
Sesterterpene MHO7 suppresses breast cancer cells as a novel estrogen receptor degrader.
Zhao Y, Zhao C, Lu J, Wu J, Li C, Hu Z, Tian W, Yang L, Xiang J, Zhou H, Deng Z, Huang J, Hong K
Pharmacological research 2019 Aug;146:104294
Pharmacological research 2019 Aug;146:104294
Proteomic analysis of murine bone marrow derived dendritic cells in response to peste des petits ruminants virus.
Li L, Wu J, Cao X, Zhou J, Yin S, Yang S, Feng Q, Du P, Liu Y, Shang Y, Liu Y, Liu X
Research in veterinary science 2019 Aug;125:195-204
Research in veterinary science 2019 Aug;125:195-204
Involvement of microRNA-23b-5p in the promotion of cardiac hypertrophy and dysfunction via the HMGB2 signaling pathway.
Boureima Oumarou D, Ji H, Xu J, Li S, Ruan W, Xiao F, Yu F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Aug;116:108977
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Aug;116:108977
Interleukin-1 receptor associated kinase (IRAK)-M -mediated type 2 microglia polarization ameliorates the severity of experimental autoimmune encephalomyelitis (EAE).
Liu B, Gu Y, Pei S, Peng Y, Chen J, Pham LV, Shen HY, Zhang J, Wang H
Journal of autoimmunity 2019 Aug;102:77-88
Journal of autoimmunity 2019 Aug;102:77-88
USP49 potently stabilizes APOBEC3G protein by removing ubiquitin and inhibits HIV-1 replication.
Pan T, Song Z, Wu L, Liu G, Ma X, Peng Z, Zhou M, Liang L, Liu B, Liu J, Zhang J, Zhang X, Huang R, Zhao J, Li Y, Ling X, Luo Y, Tang X, Cai W, Deng K, Li L, Zhang H
eLife 2019 Aug 9;8
eLife 2019 Aug 9;8
Bone marrow-derived mesenchymal stromal cells promote resistance to tyrosine kinase inhibitors in chronic myeloid leukemia via the IL-7/JAK1/STAT5 pathway.
Zhang X, Tu H, Yang Y, Jiang X, Hu X, Luo Q, Li J
The Journal of biological chemistry 2019 Aug 9;294(32):12167-12179
The Journal of biological chemistry 2019 Aug 9;294(32):12167-12179
ANLN-induced EZH2 upregulation promotes pancreatic cancer progression by mediating miR-218-5p/LASP1 signaling axis.
Wang A, Dai H, Gong Y, Zhang C, Shu J, Luo Y, Jiang Y, Liu W, Bie P
Journal of experimental & clinical cancer research : CR 2019 Aug 8;38(1):347
Journal of experimental & clinical cancer research : CR 2019 Aug 8;38(1):347
Jingfukang induces anti-cancer activity through oxidative stress-mediated DNA damage in circulating human lung cancer cells.
Que Z, Zhou Z, Luo B, Dong C, Jiang Y, Li H, Tian J
BMC complementary and alternative medicine 2019 Aug 7;19(1):204
BMC complementary and alternative medicine 2019 Aug 7;19(1):204
Platelet-Membrane-Camouflaged Black Phosphorus Quantum Dots Enhance Anticancer Effect Mediated by Apoptosis and Autophagy.
Shang Y, Wang Q, Wu B, Zhao Q, Li J, Huang X, Chen W, Gui R
ACS applied materials & interfaces 2019 Aug 7;11(31):28254-28266
ACS applied materials & interfaces 2019 Aug 7;11(31):28254-28266
Large-conductance calcium-activated potassium channels mediate lipopolysaccharide-induced activation of murine microglia.
Yang X, Wang G, Cao T, Zhang L, Ma Y, Jiang S, Teng X, Sun X
The Journal of biological chemistry 2019 Aug 30;294(35):12921-12932
The Journal of biological chemistry 2019 Aug 30;294(35):12921-12932
ORMDL3 knockdown in the lungs alleviates airway inflammation and airway remodeling in asthmatic mice via JNK1/2-MMP-9 pathway.
Wang H, Liu Y, Shi J, Cheng Z
Biochemical and biophysical research communications 2019 Aug 27;516(3):739-746
Biochemical and biophysical research communications 2019 Aug 27;516(3):739-746
Glial response in early stages of traumatic brain injury.
Zhao J, Wang B, Huang T, Guo X, Yang Z, Song J, Zhang M
Neuroscience letters 2019 Aug 24;708:134335
Neuroscience letters 2019 Aug 24;708:134335
Divergent engagements between adeno-associated viruses with their cellular receptor AAVR.
Zhang R, Xu G, Cao L, Sun Z, He Y, Cui M, Sun Y, Li S, Li H, Qin L, Hu M, Yuan Z, Rao Z, Ding W, Rao Z, Lou Z
Nature communications 2019 Aug 21;10(1):3760
Nature communications 2019 Aug 21;10(1):3760
BMAL1 Disrupted Intrinsic Diurnal Oscillation in Rat Cerebrovascular Contractility of Simulated Microgravity Rats by Altering Circadian Regulation of miR-103/Ca(V)1.2 Signal Pathway.
Chen L, Zhang B, Yang L, Bai YG, Song JB, Ge YL, Ma HZ, Cheng JH, Ma J, Xie MJ
International journal of molecular sciences 2019 Aug 14;20(16)
International journal of molecular sciences 2019 Aug 14;20(16)
Induction of Fibroblast Senescence During Mouse Corneal Wound Healing.
Wang X, Qu M, Li J, Danielson P, Yang L, Zhou Q
Investigative ophthalmology & visual science 2019 Aug 1;60(10):3669-3679
Investigative ophthalmology & visual science 2019 Aug 1;60(10):3669-3679
Temporal induction of intestinal epithelial hypoxia-inducible factor-2α is sufficient to drive colitis.
Solanki S, Devenport SN, Ramakrishnan SK, Shah YM
American journal of physiology. Gastrointestinal and liver physiology 2019 Aug 1;317(2):G98-G107
American journal of physiology. Gastrointestinal and liver physiology 2019 Aug 1;317(2):G98-G107
The fucoidan A3 from the seaweed Ascophyllum nodosum enhances RCT-related genes expression in hyperlipidemic C57BL/6J mice.
Yang Z, Yin J, Wang Y, Wang J, Xia B, Li T, Yang X, Hu S, Ji C, Guo S
International journal of biological macromolecules 2019 Aug 1;134:759-769
International journal of biological macromolecules 2019 Aug 1;134:759-769
The fucoidan from the brown seaweed Ascophyllum nodosum ameliorates atherosclerosis in apolipoprotein E-deficient mice.
Yin J, Wang J, Li F, Yang Z, Yang X, Sun W, Xia B, Li T, Song W, Guo S
Food & function 2019 Aug 1;10(8):5124-5139
Food & function 2019 Aug 1;10(8):5124-5139
The status of ω-3 PUFAs influence chronic unpredicted mild stress-induced metabolic side effects in rats through INSIG/SREBP pathway.
Tang M, Floyd S, Cai H, Zhang M, Yang R, Dang R
Food & function 2019 Aug 1;10(8):4649-4660
Food & function 2019 Aug 1;10(8):4649-4660
LncRNA THOR increases osteosarcoma cell stemness and migration by enhancing SOX9 mRNA stability.
Wu H, He Y, Chen H, Liu Y, Wei B, Chen G, Lin H, Lin H
FEBS open bio 2019 Apr;9(4):781-790
FEBS open bio 2019 Apr;9(4):781-790
Nerve growth factor prevents arsenic-induced toxicity in PC12 cells through the AKT/GSK-3β/NFAT pathway.
Tan Z, Kang T, Zhang X, Tong Y, Chen S
Journal of cellular physiology 2019 Apr;234(4):4726-4738
Journal of cellular physiology 2019 Apr;234(4):4726-4738
NLRP3 inflammasome plays an important role in caspase-1 activation and IL-1β secretion in macrophages infected with Pasteurella multocida.
Fang R, Du H, Lei G, Liu Y, Feng S, Ye C, Li N, Peng Y
Veterinary microbiology 2019 Apr;231:207-213
Veterinary microbiology 2019 Apr;231:207-213
Curcumin exerts cytotoxicity dependent on reactive oxygen species accumulation in non-small-cell lung cancer cells.
Wang C, Song X, Shang M, Zou W, Zhang M, Wei H, Shao H
Future oncology (London, England) 2019 Apr;15(11):1243-1253
Future oncology (London, England) 2019 Apr;15(11):1243-1253
Downregulation of RGMA by HIF-1A/miR-210-3p axis promotes cell proliferation in oral squamous cell carcinoma.
Lu Y, Li Y, Wang Z, Xie S, Wang Q, Lei X, Ruan Y, Li J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108608
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108608
Aspirin ameliorates lung cancer by targeting the miR-98/WNT1 axis.
Gan H, Lin L, Hu N, Yang Y, Gao Y, Pei Y, Chen K, Sun B
Thoracic cancer 2019 Apr;10(4):744-750
Thoracic cancer 2019 Apr;10(4):744-750
Human cells are permissive for the productive infection of porcine circovirus type 2 in vitro.
Liu X, Ouyang T, Ouyang H, Liu X, Niu G, Huo W, Yin W, Pang D, Ren L
Scientific reports 2019 Apr 4;9(1):5638
Scientific reports 2019 Apr 4;9(1):5638
LncRNA SNHG20 predicts a poor prognosis and promotes cell progression in epithelial ovarian cancer.
Wang D, Dai J, Hou S, Qian Y
Bioscience reports 2019 Apr 30;39(4)
Bioscience reports 2019 Apr 30;39(4)
UBE2C functions as a potential oncogene by enhancing cell proliferation, migration, invasion, and drug resistance in hepatocellular carcinoma cells.
Xiong Y, Lu J, Fang Q, Lu Y, Xie C, Wu H, Yin Z
Bioscience reports 2019 Apr 30;39(4)
Bioscience reports 2019 Apr 30;39(4)
Zearalenone Induces Estrogen-Receptor-Independent Neutrophil Extracellular Trap Release in Vitro.
Wang JJ, Wei ZK, Han Z, Liu ZY, Zhu XY, Li XW, Wang K, Yang ZT
Journal of agricultural and food chemistry 2019 Apr 24;67(16):4588-4594
Journal of agricultural and food chemistry 2019 Apr 24;67(16):4588-4594
Excessive miR-25-3p maturation via N(6)-methyladenosine stimulated by cigarette smoke promotes pancreatic cancer progression.
Zhang J, Bai R, Li M, Ye H, Wu C, Wang C, Li S, Tan L, Mai D, Li G, Pan L, Zheng Y, Su J, Ye Y, Fu Z, Zheng S, Zuo Z, Liu Z, Zhao Q, Che X, Xie D, Jia W, Zeng MS, Tan W, Chen R, Xu RH, Zheng J, Lin D
Nature communications 2019 Apr 23;10(1):1858
Nature communications 2019 Apr 23;10(1):1858
Icariin attenuates neuroinflammation and exerts dopamine neuroprotection via an Nrf2-dependent manner.
Zhang B, Wang G, He J, Yang Q, Li D, Li J, Zhang F
Journal of neuroinflammation 2019 Apr 22;16(1):92
Journal of neuroinflammation 2019 Apr 22;16(1):92
Ntrk1 Promotes Resistance to PD-1 Checkpoint Blockade in Mesenchymal Kras/p53 Mutant Lung Cancer.
Konen JM, Rodriguez BL, Fradette JJ, Gibson L, Davis D, Minelli R, Peoples MD, Kovacs J, Carugo A, Bristow C, Heffernan T, Gibbons DL
Cancers 2019 Apr 2;11(4)
Cancers 2019 Apr 2;11(4)
Macrophage migration inhibitory factor facilitates prostaglandin E(2) production of astrocytes to tune inflammatory milieu following spinal cord injury.
Zhang Y, Zhou Y, Chen S, Hu Y, Zhu Z, Wang Y, Du N, Song T, Yang Y, Guo A, Wang Y
Journal of neuroinflammation 2019 Apr 13;16(1):85
Journal of neuroinflammation 2019 Apr 13;16(1):85
MicroRNA-106b Regulates Milk Fat Metabolism via ATP Binding Cassette Subfamily A Member 1 ( ABCA1) in Bovine Mammary Epithelial Cells.
Chen Z, Chu S, Wang X, Fan Y, Zhan T, Arbab AAI, Li M, Zhang H, Mao Y, Loor JJ, Yang Z
Journal of agricultural and food chemistry 2019 Apr 10;67(14):3981-3990
Journal of agricultural and food chemistry 2019 Apr 10;67(14):3981-3990
Immunomodulatory effects of an acidic polysaccharide fraction from herbal Gynostemma pentaphyllum tea in RAW264.7 cells.
Ren D, Zhao Y, Zheng Q, Alim A, Yang X
Food & function 2019 Apr 1;10(4):2186-2197
Food & function 2019 Apr 1;10(4):2186-2197
Exosomal ephrinA2 derived from serum as a potential biomarker for prostate cancer.
Li S, Zhao Y, Chen W, Yin L, Zhu J, Zhang H, Cai C, Li P, Huang L, Ma P
Journal of Cancer 2018;9(15):2659-2665
Journal of Cancer 2018;9(15):2659-2665
AMPH-1 is critical for breast cancer progression.
Chen Y, Liu J, Li L, Xia H, Lin Z, Zhong T
Journal of Cancer 2018;9(12):2175-2182
Journal of Cancer 2018;9(12):2175-2182
The Protective Effect of Astaxanthin on Cognitive Function via Inhibition of Oxidative Stress and Inflammation in the Brains of Chronic T2DM Rats.
Feng Y, Chu A, Luo Q, Wu M, Shi X, Chen Y
Frontiers in pharmacology 2018;9:748
Frontiers in pharmacology 2018;9:748
Maternal Protein Restriction Induces Alterations in Hepatic Unfolded Protein Response-Related Molecules in Adult Rat Offspring.
Liu X, Wang J, Gao L, Jiao Y, Liu C
Frontiers in endocrinology 2018;9:676
Frontiers in endocrinology 2018;9:676
β-TrCP Restricts Lipopolysaccharide (LPS)-Induced Activation of TRAF6-IKK Pathway Upstream of IκBα Signaling.
Liu J, Yuan Y, Xu J, Xiao K, Xu Y, Guo T, Zhang L, Wang J, Zheng H
Frontiers in immunology 2018;9:2930
Frontiers in immunology 2018;9:2930
The Host Restriction Factor Interferon-Inducible Transmembrane Protein 3 Inhibits Vaccinia Virus Infection.
Li C, Du S, Tian M, Wang Y, Bai J, Tan P, Liu W, Yin R, Wang M, Jiang Y, Li Y, Zhu N, Zhu Y, Li T, Wu S, Jin N, He F
Frontiers in immunology 2018;9:228
Frontiers in immunology 2018;9:228
Protective Effect of Extract of Bletilla Striata on Isoflurane Induced Neuronal Injury By Altering PI3K/Akt Pathway.
Zhao G, Li K, Chen J, Li L
Translational neuroscience 2018;9:183-189
Translational neuroscience 2018;9:183-189
Magnolol Alleviates Inflammatory Responses and Lipid Accumulation by AMP-Activated Protein Kinase-Dependent Peroxisome Proliferator-Activated Receptor α Activation.
Tian Y, Feng H, Han L, Wu L, Lv H, Shen B, Li Z, Zhang Q, Liu G
Frontiers in immunology 2018;9:147
Frontiers in immunology 2018;9:147
Geniposide and Chlorogenic Acid Combination Ameliorates Non-alcoholic Steatohepatitis Involving the Protection on the Gut Barrier Function in Mouse Induced by High-Fat Diet.
Peng JH, Leng J, Tian HJ, Yang T, Fang Y, Feng Q, Zhao Y, Hu YY
Frontiers in pharmacology 2018;9:1399
Frontiers in pharmacology 2018;9:1399
Oncolytic Newcastle disease virus induces autophagy-dependent immunogenic cell death in lung cancer cells.
Ye T, Jiang K, Wei L, Barr MP, Xu Q, Zhang G, Ding C, Meng S, Piao H
American journal of cancer research 2018;8(8):1514-1527
American journal of cancer research 2018;8(8):1514-1527
Add-On therapy with Chinese herb medicine Bo-Er-Ning capsule (BENC) improves outcomes of gastric cancer patients: a randomized clinical trial followed with bioinformatics-assisted mechanism study.
Pan B, Zang J, He J, Wang Z, Liu L
American journal of cancer research 2018;8(6):1090-1105
American journal of cancer research 2018;8(6):1090-1105
Liposomal Curcumin Targeting Endometrial Cancer Through the NF-κB Pathway.
Xu H, Gong Z, Zhou S, Yang S, Wang D, Chen X, Wu J, Liu L, Zhong S, Zhao J, Tang J
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(2):569-582
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(2):569-582
Placental growth factor promotes epithelial-mesenchymal transition-like changes in ARPE-19 cells under hypoxia.
Zhang Y, Zhao L, Wang L, Yang X, Zhou A, Wang J
Molecular vision 2018;24:340-352
Molecular vision 2018;24:340-352
Dorsal Root Ganglion Maintains Stemness of Bone Marrow Mesenchymal Stem Cells by Enhancing Autophagy through the AMPK/mTOR Pathway in a Coculture System.
Zhang S, Li J, Jiang H, Gao Y, Cheng P, Cao T, Li D, Wang J, Song Y, Liu B, Wu H, Wang C, Yang L, Pei G
Stem cells international 2018;2018:8478953
Stem cells international 2018;2018:8478953
Glucagon-Like Peptide-1 Mediates the Protective Effect of the Dipeptidyl Peptidase IV Inhibitor on Renal Fibrosis via Reducing the Phenotypic Conversion of Renal Microvascular Cells in Monocrotaline-Treated Rats.
Xu J, Wang J, Cheng Y, Li X, He M, Zhu J, Han H, Wei G, Kong H, Xie W, Wang H, Zuo X
BioMed research international 2018;2018:1864107
BioMed research international 2018;2018:1864107
Oxidative stress and NF-κB signaling are involved in LPS induced pulmonary dysplasia in chick embryos.
Long Y, Wang G, Li K, Zhang Z, Zhang P, Zhang J, Zhang X, Bao Y, Yang X, Wang P
Cell cycle (Georgetown, Tex.) 2018;17(14):1757-1771
Cell cycle (Georgetown, Tex.) 2018;17(14):1757-1771
Foot-and-mouth disease virus capsid protein VP2 activates the cellular EIF2S1-ATF4 pathway and induces autophagy via HSPB1.
Sun P, Zhang S, Qin X, Chang X, Cui X, Li H, Zhang S, Gao H, Wang P, Zhang Z, Luo J, Li Z
Autophagy 2018;14(2):336-346
Autophagy 2018;14(2):336-346
TRIM59 regulates autophagy through modulating both the transcription and the ubiquitination of BECN1.
Han T, Guo M, Gan M, Yu B, Tian X, Wang JB
Autophagy 2018;14(12):2035-2048
Autophagy 2018;14(12):2035-2048
Linagliptin unmasks specific antioxidant pathways protective against albuminuria and kidney hypertrophy in a mouse model of diabetes.
Spencer NY, Yang Z, Sullivan JC, Klein T, Stanton RC
PloS one 2018;13(7):e0200249
PloS one 2018;13(7):e0200249
Dysregulation of Neuregulin-1/ErbB signaling in the hippocampus of rats after administration of doxorubicin.
Liao D, Guo Y, Xiang D, Dang R, Xu P, Cai H, Cao L, Jiang P
Drug design, development and therapy 2018;12:231-239
Drug design, development and therapy 2018;12:231-239
Involvement of microRNA-146a in diabetic peripheral neuropathy through the regulation of inflammation.
Feng Y, Chen L, Luo Q, Wu M, Chen Y, Shi X
Drug design, development and therapy 2018;12:171-177
Drug design, development and therapy 2018;12:171-177
Expression and significance of the Hedgehog signal transduction pathway in oxygen-induced retinal neovascularization in mice.
Liu M, Chen X, Liu H, Di Y
Drug design, development and therapy 2018;12:1337-1346
Drug design, development and therapy 2018;12:1337-1346
miR-222-3p promotes osteosarcoma cell migration and invasion through targeting TIMP3.
Guo J, Liu Q, Li Z, Guo H, Bai C, Wang F
OncoTargets and therapy 2018;11:8643-8653
OncoTargets and therapy 2018;11:8643-8653
Protective Effect of Hydrogen on Sodium Iodate-Induced Age-Related Macular Degeneration in Mice.
Liu Y, Li R, Xie J, Hu J, Huang X, Ren F, Li L
Frontiers in aging neuroscience 2018;10:389
Frontiers in aging neuroscience 2018;10:389
Dl-3-n-Butylphthalide improves lipopolysaccharide-induced depressive-like behavior in rats: involvement of Nrf2 and NF-κB pathways.
Yang M, Dang R, Xu P, Guo Y, Han W, Liao D, Jiang P
Psychopharmacology 2018 Sep;235(9):2573-2585
Psychopharmacology 2018 Sep;235(9):2573-2585
miR-34b-5p inhibition attenuates lung inflammation and apoptosis in an LPS-induced acute lung injury mouse model by targeting progranulin.
Xie W, Lu Q, Wang K, Lu J, Gu X, Zhu D, Liu F, Guo Z
Journal of cellular physiology 2018 Sep;233(9):6615-6631
Journal of cellular physiology 2018 Sep;233(9):6615-6631
Amyotrophic lateral sclerosis (ALS) and Alzheimer's disease (AD) are characterised by differential activation of ER stress pathways: focus on UPR target genes.
Montibeller L, de Belleroche J
Cell stress & chaperones 2018 Sep;23(5):897-912
Cell stress & chaperones 2018 Sep;23(5):897-912
Exosomal zinc transporter ZIP4 promotes cancer growth and is a novel diagnostic biomarker for pancreatic cancer.
Jin H, Liu P, Wu Y, Meng X, Wu M, Han J, Tan X
Cancer science 2018 Sep;109(9):2946-2956
Cancer science 2018 Sep;109(9):2946-2956
Disruption of Tmem30a results in cerebellar ataxia and degeneration of Purkinje cells.
Yang Y, Sun K, Liu W, Zhang L, Peng K, Zhang S, Li S, Yang M, Jiang Z, Lu F, Zhu X
Cell death & disease 2018 Sep 5;9(9):899
Cell death & disease 2018 Sep 5;9(9):899
The regulatory effects of metformin on the [SNAIL/miR-34]:[ZEB/miR-200] system in the epithelial-mesenchymal transition(EMT) for colorectal cancer(CRC).
Wang Y, Wu Z, Hu L
European journal of pharmacology 2018 Sep 5;834:45-53
European journal of pharmacology 2018 Sep 5;834:45-53
Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors.
Huang X, Yan J, Zhang M, Wang Y, Chen Y, Fu X, Wei R, Zheng XL, Liu Z, Zhang X, Yang H, Hao B, Shen YY, Su Y, Cong X, Huang M, Tan M, Ding J, Geng M
Cell 2018 Sep 20;175(1):186-199.e19
Cell 2018 Sep 20;175(1):186-199.e19
Transcriptomic but not genomic variability confers phenotype of breast cancer stem cells.
Tong M, Deng Z, Yang M, Xu C, Zhang X, Zhang Q, Liao Y, Deng X, Lv D, Zhang X, Zhang Y, Li P, Song L, Wang B, Al-Dherasi A, Li Z, Liu Q
Cancer communications (London, England) 2018 Sep 19;38(1):56
Cancer communications (London, England) 2018 Sep 19;38(1):56
Cattle Encephalon Glycoside and Ignotin Reduce Early Brain Injury and Cognitive Dysfunction after Subarachnoid Hemorrhage in Rats.
Ma K, Li R, Zhao H, Qu J, Mu N, Liu X, Wang S, Yang C, Feng H, Tan L, Li F
Neuroscience 2018 Sep 15;388:181-190
Neuroscience 2018 Sep 15;388:181-190
Cutting Edge: Dysregulated CARD9 Signaling in Neutrophils Drives Inflammation in a Mouse Model of Neutrophilic Dermatoses.
Tartey S, Gurung P, Samir P, Burton A, Kanneganti TD
Journal of immunology (Baltimore, Md. : 1950) 2018 Sep 15;201(6):1639-1644
Journal of immunology (Baltimore, Md. : 1950) 2018 Sep 15;201(6):1639-1644
Resveratrol Suppresses Matrix Metalloproteinase-2 Activation Induced by Lipopolysaccharide in Mouse Osteoblasts via Interactions with AMP-Activated Protein Kinase and Suppressor of Cytokine Signaling 1.
Yu Y, Li X, Mi J, Qu L, Yang D, Guo J, Qiu L
Molecules (Basel, Switzerland) 2018 Sep 12;23(9)
Molecules (Basel, Switzerland) 2018 Sep 12;23(9)
The apoptosis in arsenic-induced oxidative stress is associated with autophagy in the testis tissues of chicken.
Shao YZ, Zhao HJ, Wang Y, Liu JJ, Li JL, Luo LY, Xing MW
Poultry science 2018 Sep 1;97(9):3248-3257
Poultry science 2018 Sep 1;97(9):3248-3257
Dipeptidyl peptidase IV (DPP-4) inhibition alleviates pulmonary arterial remodeling in experimental pulmonary hypertension.
Xu J, Wang J, He M, Han H, Xie W, Wang H, Kong H
Laboratory investigation; a journal of technical methods and pathology 2018 Oct;98(10):1333-1346
Laboratory investigation; a journal of technical methods and pathology 2018 Oct;98(10):1333-1346
Bone morphogenetic protein 4 expression in the developing lumbosacral spinal cord of rat embryos with anorectal malformations.
Yang Z, Jia H, Bai Y, Wang W
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2018 Oct;69:32-38
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2018 Oct;69:32-38
MicroRNA-543 functions as an osteogenesis promoter in human periodontal ligament-derived stem cells by inhibiting transducer of ERBB2, 2.
Ge Y, Li J, Hao Y, Hu Y, Chen D, Wu B, Fang F
Journal of periodontal research 2018 Oct;53(5):832-841
Journal of periodontal research 2018 Oct;53(5):832-841
Curcumol induces RIPK1/RIPK3 complex-dependent necroptosis via JNK1/2-ROS signaling in hepatic stellate cells.
Jia Y, Wang F, Guo Q, Li M, Wang L, Zhang Z, Jiang S, Jin H, Chen A, Tan S, Zhang F, Shao J, Zheng S
Redox biology 2018 Oct;19:375-387
Redox biology 2018 Oct;19:375-387
Quantitative Global Proteome and Lysine Succinylome Analyses Reveal the Effects of Energy Metabolism in Renal Cell Carcinoma.
Zhang N, Gao R, Yang J, Zhu Y, Zhang Z, Xu X, Wang J, Liu X, Li Z, Li Z, Gong D, Li J, Bi J, Kong C
Proteomics 2018 Oct;18(19):e1800001
Proteomics 2018 Oct;18(19):e1800001
Salidroside attenuates endothelial cellular senescence via decreasing the expression of inflammatory cytokines and increasing the expression of SIRT3.
Xing SS, Li J, Chen L, Yang YF, He PL, Li J, Yang J
Mechanisms of ageing and development 2018 Oct;175:1-6
Mechanisms of ageing and development 2018 Oct;175:1-6
TRIM65 supports bladder urothelial carcinoma cell aggressiveness by promoting ANXA2 ubiquitination and degradation.
Wei WS, Chen X, Guo LY, Li XD, Deng MH, Yuan GJ, He LY, Li YH, Zhang ZL, Jiang LJ, Chen RX, Ma XD, Wei S, Ma NF, Liu ZW, Luo JH, Zhou FJ, Xie D
Cancer letters 2018 Oct 28;435:10-22
Cancer letters 2018 Oct 28;435:10-22
Cyclophilin J limits inflammation through the blockage of ubiquitin chain sensing.
Sheng C, Yao C, Wang Z, Chen H, Zhao Y, Xu D, Huang H, Huang W, Chen S
Nature communications 2018 Oct 22;9(1):4381
Nature communications 2018 Oct 22;9(1):4381
Quercetin ameliorates podocyte injury via inhibition of oxidative stress and the TGF-β1/Smad pathway in DN rats.
Gao F, He X, Liang S, Liu S, Liu H, He Q, Chen L, Jiang H, Zhang Y
RSC advances 2018 Oct 15;8(62):35413-35421
RSC advances 2018 Oct 15;8(62):35413-35421
Apelin-13 Upregulates BDNF Against Chronic Stress-induced Depression-like Phenotypes by Ameliorating HPA Axis and Hippocampal Glucocorticoid Receptor Dysfunctions.
Dai TT, Wang B, Xiao ZY, You Y, Tian SW
Neuroscience 2018 Oct 15;390:151-159
Neuroscience 2018 Oct 15;390:151-159
Reduced graphene oxide triggered epithelial-mesenchymal transition in A549 cells.
Liao Y, Wang W, Huang X, Sun Y, Tian S, Cai P
Scientific reports 2018 Oct 12;8(1):15188
Scientific reports 2018 Oct 12;8(1):15188
Andrographolide inhibits breast cancer through suppressing COX-2 expression and angiogenesis via inactivation of p300 signaling and VEGF pathway.
Peng Y, Wang Y, Tang N, Sun D, Lan Y, Yu Z, Zhao X, Feng L, Zhang B, Jin L, Yu F, Ma X, Lv C
Journal of experimental & clinical cancer research : CR 2018 Oct 12;37(1):248
Journal of experimental & clinical cancer research : CR 2018 Oct 12;37(1):248
SUMO-1 modification of FEN1 facilitates its interaction with Rad9-Rad1-Hus1 to counteract DNA replication stress.
Xu X, Shi R, Zheng L, Guo Z, Wang L, Zhou M, Zhao Y, Tian B, Truong K, Chen Y, Shen B, Hua Y, Xu H
Journal of molecular cell biology 2018 Oct 1;10(5):460-474
Journal of molecular cell biology 2018 Oct 1;10(5):460-474
Fluoride induces apoptosis and autophagy through the IL-17 signaling pathway in mice hepatocytes.
Zhao Y, Li Y, Wang J, Manthari RK, Wang J
Archives of toxicology 2018 Nov;92(11):3277-3289
Archives of toxicology 2018 Nov;92(11):3277-3289
Atorvastatin Pretreatment Attenuates Ischemic Brain Edema by Suppressing Aquaporin 4.
Cheng ZJ, Dai TM, Shen YY, He JL, Li J, Tu JL
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2018 Nov;27(11):3247-3255
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2018 Nov;27(11):3247-3255
Oncogenic activation of PI3K induces progenitor cell differentiation to suppress epidermal growth.
Ying Z, Sandoval M, Beronja S
Nature cell biology 2018 Nov;20(11):1256-1266
Nature cell biology 2018 Nov;20(11):1256-1266
(2R,3R)Dihydromyricetin inhibits osteoclastogenesis and bone loss through scavenging LPS-induced oxidative stress and NF-κB and MAPKs pathways activating.
Zhang X, Li X, Fang J, Hou X, Fang H, Guo F, Li F, Chen A, Huang S
Journal of cellular biochemistry 2018 Nov;119(11):8981-8995
Journal of cellular biochemistry 2018 Nov;119(11):8981-8995
NR2B-Tyr phosphorylation regulates synaptic plasticity in central sensitization in a chronic migraine rat model.
Wang XY, Zhou HR, Wang S, Liu CY, Qin GC, Fu QQ, Zhou JY, Chen LX
The journal of headache and pain 2018 Nov 6;19(1):102
The journal of headache and pain 2018 Nov 6;19(1):102
MicroRNA-32 Regulates Development and Progression of Hepatocellular Carcinoma by Targeting ADAMTS9 and Affects Its Prognosis.
Li S, Li T, Li X, Yao Y, Jiang X, Zhao L, Guo W
Medical science monitor basic research 2018 Nov 5;24:177-187
Medical science monitor basic research 2018 Nov 5;24:177-187
Zinc finger E-box-binding homeobox 1 mediates aerobic glycolysis via suppression of sirtuin 3 in pancreatic cancer.
Xu WY, Hu QS, Qin Y, Zhang B, Liu WS, Ni QX, Xu J, Yu XJ
World journal of gastroenterology 2018 Nov 21;24(43):4893-4905
World journal of gastroenterology 2018 Nov 21;24(43):4893-4905
Estrogen receptor β upregulated by lncRNA-H19 to promote cancer stem-like properties in papillary thyroid carcinoma.
Li M, Chai HF, Peng F, Meng YT, Zhang LZ, Zhang L, Zou H, Liang QL, Li MM, Mao KG, Sun DX, Tong MY, Deng ZQ, Hou ZJ, Zhao Y, Li J, Wang XC, Lv SS, Zhang QQ, Yu X, Lam EW, Liu Q, Cui XN, Xu J
Cell death & disease 2018 Nov 2;9(11):1120
Cell death & disease 2018 Nov 2;9(11):1120
Citrus Tangeretin Improves Skeletal Muscle Mitochondrial Biogenesis via Activating the AMPK-PGC1-α Pathway In Vitro and In Vivo: A Possible Mechanism for Its Beneficial Effect on Physical Performance.
Kou G, Li Z, Wu C, Liu Y, Hu Y, Guo L, Xu X, Zhou Z
Journal of agricultural and food chemistry 2018 Nov 14;66(45):11917-11925
Journal of agricultural and food chemistry 2018 Nov 14;66(45):11917-11925
Nitric oxide triggers the assembly of "type II" stress granules linked to decreased cell viability.
Aulas A, Lyons SM, Fay MM, Anderson P, Ivanov P
Cell death & disease 2018 Nov 13;9(11):1129
Cell death & disease 2018 Nov 13;9(11):1129
Inhibitor of Bruton's tyrosine kinases, PCI-32765, decreases pro-inflammatory mediators' production in high glucose-induced macrophages.
Fan Z, Wang Y, Xu X, Wu Y
International immunopharmacology 2018 May;58:145-153
International immunopharmacology 2018 May;58:145-153
Overexpression of collagen type V α1 chain in human breast invasive ductal carcinoma is mediated by TGF-β1.
Ren W, Zhang Y, Zhang L, Lin Q, Zhang J, Xu G
International journal of oncology 2018 May;52(5):1694-1704
International journal of oncology 2018 May;52(5):1694-1704
Establishment of a human embryonic stem cell line with homozygous TP53 R248W mutant by TALEN mediated gene editing.
Xu A, Zhou R, Tu J, Huo Z, Zhu D, Wang D, Gingold JA, Mata H, Rao PH, Liu M, Mohamed AMT, Kong CSL, Jewell BE, Xia W, Zhao R, Hung MC, Lee DF
Stem cell research 2018 May;29:215-219
Stem cell research 2018 May;29:215-219
Induction of OTUD1 by RNA viruses potently inhibits innate immune responses by promoting degradation of the MAVS/TRAF3/TRAF6 signalosome.
Zhang L, Liu J, Qian L, Feng Q, Wang X, Yuan Y, Zuo Y, Cheng Q, Miao Y, Guo T, Zheng X, Zheng H
PLoS pathogens 2018 May;14(5):e1007067
PLoS pathogens 2018 May;14(5):e1007067
Systemic administration of scAAV9-IGF1 extends survival in SOD1(G93A) ALS mice via inhibiting p38 MAPK and the JNK-mediated apoptosis pathway.
Wang W, Wen D, Duan W, Yin J, Cui C, Wang Y, Li Z, Liu Y, Li C
Brain research bulletin 2018 May;139:203-210
Brain research bulletin 2018 May;139:203-210
Exogenous leptin affects sperm parameters and impairs blood testis barrier integrity in adult male mice.
Wang X, Zhang X, Hu L, Li H
Reproductive biology and endocrinology : RB&E 2018 May 31;16(1):55
Reproductive biology and endocrinology : RB&E 2018 May 31;16(1):55
Promotion of autophagosome-lysosome fusion via salvianolic acid A-mediated SIRT1 up-regulation ameliorates alcoholic liver disease.
Shi X, Sun R, Zhao Y, Fu R, Wang R, Zhao H, Wang Z, Tang F, Zhang N, Tian X, Yao J
RSC advances 2018 May 30;8(36):20411-20422
RSC advances 2018 May 30;8(36):20411-20422
IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation.
Karki R, Lee E, Place D, Samir P, Mavuluri J, Sharma BR, Balakrishnan A, Malireddi RKS, Geiger R, Zhu Q, Neale G, Kanneganti TD
Cell 2018 May 3;173(4):920-933.e13
Cell 2018 May 3;173(4):920-933.e13
Effect of propolis on preserving human periodontal ligament cells and regulating pro-inflammatory cytokines.
Yuan XJ, Wang YY, Shi BQ, Zhao YM
Dental traumatology : official publication of International Association for Dental Traumatology 2018 May 27;
Dental traumatology : official publication of International Association for Dental Traumatology 2018 May 27;
Hepatoprotection of auraptene from peels of citrus fruits against thioacetamide-induced hepatic fibrosis in mice by activating farnesoid X receptor.
Gao X, Wang C, Ning C, Liu K, Wang X, Liu Z, Sun H, Ma X, Sun P, Meng Q
Food & function 2018 May 23;9(5):2684-2694
Food & function 2018 May 23;9(5):2684-2694
TRIM50 suppressed hepatocarcinoma progression through directly targeting SNAIL for ubiquitous degradation.
Ma X, Ma X, Qiu Y, Zhu L, Lin Y, You Y, Ma D, Qin Z, Sun C, Zhao Y, Sun Y, Han L
Cell death & disease 2018 May 22;9(6):608
Cell death & disease 2018 May 22;9(6):608
Geniposide attenuates Aβ(25-35)-induced neurotoxicity via the TLR4/NF-κB pathway in HT22 cells.
Huang XF, Li JJ, Tao YG, Wang XQ, Zhang RL, Zhang JL, Su ZQ, Huang QH, Deng YH
RSC advances 2018 May 22;8(34):18926-18937
RSC advances 2018 May 22;8(34):18926-18937
Renal protective effect of Paeoniflorin by inhibition of JAK2/STAT3 signaling pathway in diabetic mice.
Li X, Wang Y, Wang K, Wu Y
Bioscience trends 2018 May 13;12(2):168-176
Bioscience trends 2018 May 13;12(2):168-176
Cell Cycle Regulation by Alternative Polyadenylation of CCND1.
Wang Q, He G, Hou M, Chen L, Chen S, Xu A, Fu Y
Scientific reports 2018 May 1;8(1):6824
Scientific reports 2018 May 1;8(1):6824
Dietary α-Mangostin Provides Protective Effects against Acetaminophen-Induced Hepatotoxicity in Mice via Akt/mTOR-Mediated Inhibition of Autophagy and Apoptosis.
Yan XT, Sun YS, Ren S, Zhao LC, Liu WC, Chen C, Wang Z, Li W
International journal of molecular sciences 2018 May 1;19(5)
International journal of molecular sciences 2018 May 1;19(5)
ASK1/2 signaling promotes inflammation in a mouse model of neutrophilic dermatosis.
Tartey S, Gurung P, Dasari TK, Burton A, Kanneganti TD
The Journal of clinical investigation 2018 May 1;128(5):2042-2047
The Journal of clinical investigation 2018 May 1;128(5):2042-2047
Innately activated TLR4 signal in the nucleus accumbens is sustained by CRF amplification loop and regulates impulsivity.
Balan I, Warnock KT, Puche A, Gondre-Lewis MC, Aurelian L
Brain, behavior, and immunity 2018 Mar;69:139-153
Brain, behavior, and immunity 2018 Mar;69:139-153
Effects of gelling bath on the physical properties of alginate gel beads and the biological characteristics of entrapped HepG2 cells.
Sun D, Liu Y, Wu H, Ren Y, Ma X, Wu H, Sun G
Biotechnology and applied biochemistry 2018 Mar;65(2):263-273
Biotechnology and applied biochemistry 2018 Mar;65(2):263-273
Insulin Treatment Cannot Promote Lipogenesis in Rat Fetal Lung in Gestational Diabetes Mellitus Because of Failure to Redress the Imbalance Among SREBP-1, SCAP, and INSIG-1.
Li J, Qian G, Zhong X, Yu T
DNA and cell biology 2018 Mar;37(3):264-270
DNA and cell biology 2018 Mar;37(3):264-270
Ubenimex, an APN inhibitor, could serve as an anti‑tumor drug in RT112 and 5637 cells by operating in an Akt‑associated manner.
Wang X, Liu Y, Liu W, Zhang Y, Guo F, Zhang L, Cui M, Liu S, Wu R
Molecular medicine reports 2018 Mar;17(3):4531-4539
Molecular medicine reports 2018 Mar;17(3):4531-4539
LIFR increases the release of soluble endoglin via the upregulation of MMP14 expression in preeclampsia.
Li H, Yao J, Chang X, Wu J, Duan T, Wang K
Reproduction (Cambridge, England) 2018 Mar;155(3):297-306
Reproduction (Cambridge, England) 2018 Mar;155(3):297-306
7α,8α-Epoxynagilactones and their glucosides from the twigs of Podocarpus nagi: Isolation, structures, and cytotoxic activities.
Zheng YD, Bai G, Tang C, Ke CQ, Yao S, Tong LJ, Feng F, Li Y, Ding J, Xie H, Ye Y
Fitoterapia 2018 Mar;125:174-183
Fitoterapia 2018 Mar;125:174-183
Elucidation of the Molecular-Mechanisms and In Vivo Evaluation of the Anti-inflammatory Effect of Alginate-Derived Seleno-polymannuronate.
Bi D, Lai Q, Cai N, Li T, Zhang Y, Han Q, Peng Y, Xu H, Lu J, Bao W, Liu Q, Xu X
Journal of agricultural and food chemistry 2018 Mar 7;66(9):2083-2091
Journal of agricultural and food chemistry 2018 Mar 7;66(9):2083-2091
Nicotine-Induced Neuroprotection against Cognitive Dysfunction after Partial Hepatectomy Involves Activation of BDNF/TrkB Signaling Pathway and Inhibition of NF-κB Signaling Pathway in Aged Rats.
Wei P, Zheng Q, Liu H, Wan T, Zhou J, Li D, Zhou H, Li J, Ji F, Tang W, Li J
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2018 Mar 6;20(4):515-522
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2018 Mar 6;20(4):515-522
Correction and Republication: Effect of Di-(2-ethylhexyl) phthalate on the hypothalamus-pituitary-thyroid axis in adolescent rat.
Sun D, Zhou L, Wang S, Liu T, Zhu J, Jia Y, Xu J, Chen H, Wang Q, Xu F, Zhang Y, Ye L
Endocrine journal 2018 Mar 28;65(3):261-268
Endocrine journal 2018 Mar 28;65(3):261-268
Exosomes from C2C12 myoblasts enhance osteogenic differentiation of MC3T3-E1 pre-osteoblasts by delivering miR-27a-3p.
Xu Q, Cui Y, Luan J, Zhou X, Li H, Han J
Biochemical and biophysical research communications 2018 Mar 25;498(1):32-37
Biochemical and biophysical research communications 2018 Mar 25;498(1):32-37
New Drug Candidate Targeting the 4A1 Orphan Nuclear Receptor for Medullary Thyroid Cancer Therapy.
Zhang L, Liu W, Wang Q, Li Q, Wang H, Wang J, Teng T, Chen M, Ji A, Li Y
Molecules (Basel, Switzerland) 2018 Mar 2;23(3)
Molecules (Basel, Switzerland) 2018 Mar 2;23(3)
Apoptosome formation upon overexpression of native and truncated Apaf-1 in cell-free and cell-based systems.
Noori AR, Hosseini ES, Nikkhah M, Hosseinkhani S
Archives of biochemistry and biophysics 2018 Mar 15;642:46-51
Archives of biochemistry and biophysics 2018 Mar 15;642:46-51
Mitochondrial Dysfunctions Contribute to Hypertrophic Cardiomyopathy in Patient iPSC-Derived Cardiomyocytes with MT-RNR2 Mutation.
Li S, Pan H, Tan C, Sun Y, Song Y, Zhang X, Yang W, Wang X, Li D, Dai Y, Ma Q, Xu C, Zhu X, Kang L, Fu Y, Xu X, Shu J, Zhou N, Han F, Qin D, Huang W, Liu Z, Yan Q
Stem cell reports 2018 Mar 13;10(3):808-821
Stem cell reports 2018 Mar 13;10(3):808-821
Cell division cycle 7 is a potential therapeutic target in oral squamous cell carcinoma and is regulated by E2F1.
Jin S, Ma H, Yang W, Ju H, Wang L, Zhang Z
Journal of molecular medicine (Berlin, Germany) 2018 Jun;96(6):513-525
Journal of molecular medicine (Berlin, Germany) 2018 Jun;96(6):513-525
IL-6 receptor blockade ameliorates diabetic nephropathy via inhibiting inflammasome in mice.
Wu R, Liu X, Yin J, Wu H, Cai X, Wang N, Qian Y, Wang F
Metabolism: clinical and experimental 2018 Jun;83:18-24
Metabolism: clinical and experimental 2018 Jun;83:18-24
Metformin inhibits ovarian cancer via decreasing H3K27 trimethylation.
Tang G, Guo J, Zhu Y, Huang Z, Liu T, Cai J, Yu L, Wang Z
International journal of oncology 2018 Jun;52(6):1899-1911
International journal of oncology 2018 Jun;52(6):1899-1911
Avian leukosis virus subgroup J promotes cell proliferation and cell cycle progression through miR-221 by targeting CDKN1B.
Ren C, Yu M, Zhang Y, Fan M, Chang F, Xing L, Liu Y, Wang Y, Qi X, Liu C, Zhang Y, Cui H, Li K, Gao L, Pan Q, Wang X, Gao Y
Virology 2018 Jun;519:121-130
Virology 2018 Jun;519:121-130
PEDF improves cardiac function in rats subjected to myocardial ischemia/reperfusion injury by inhibiting ROS generation via PEDF‑R.
Zhao Q, Liu Z, Huang B, Yuan Y, Liu X, Zhang H, Qiu F, Zhang Y, Li Y, Miao H, Dong H, Zhang Z
International journal of molecular medicine 2018 Jun;41(6):3243-3252
International journal of molecular medicine 2018 Jun;41(6):3243-3252
Effect of Banxia Xiexin decoction on Helicobacter pylori-related peptic ulcers and its possible mechanism via the TGF-β/Smad signaling pathway.
Chen S, Huang Y, Wan S, Huang Y, Liang H, Chen S
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2018 Jun;38(3):419-426
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2018 Jun;38(3):419-426
Doxycycline attenuates chronic intermittent hypoxia-induced atrial fibrosis in rats.
Wang W, Zhang K, Li X, Ma Z, Zhang Y, Yuan M, Suo Y, Liang X, Tse G, Goudis CA, Liu T, Li G
Cardiovascular therapeutics 2018 Jun;36(3):e12321
Cardiovascular therapeutics 2018 Jun;36(3):e12321
Cysteine-rich protein 61 regulates adipocyte differentiation from mesenchymal stem cells through mammalian target of rapamycin complex 1 and canonical Wnt signaling.
Yang Y, Qi Q, Wang Y, Shi Y, Yang W, Cen Y, Zhu E, Li X, Chen D, Wang B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Jun;32(6):3096-3107
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Jun;32(6):3096-3107
A comparison of CRISPR/Cas9 and siRNA-mediated ALDH2 gene silencing in human cell lines.
Wang F, Guo T, Jiang H, Li R, Wang T, Zeng N, Dong G, Zeng X, Li D, Xiao Y, Hu Q, Chen W, Xing X, Wang Q
Molecular genetics and genomics : MGG 2018 Jun;293(3):769-783
Molecular genetics and genomics : MGG 2018 Jun;293(3):769-783
Effects of nicotine on the metabolism and gene expression profile of Sprague‑Dawley rat primary osteoblasts.
Liang D, Wang KJ, Tang ZQ, Liu RH, Zeng F, Cheng MY, Lian QS, Wu HK
Molecular medicine reports 2018 Jun;17(6):8269-8281
Molecular medicine reports 2018 Jun;17(6):8269-8281
Myxovirus resistance protein A inhibits hepatitis C virus replication through JAK-STAT pathway activation.
Wang H, Xin X, Wang M, Han L, Li J, Hao Y, Zheng C, Shen C
Archives of virology 2018 Jun;163(6):1429-1438
Archives of virology 2018 Jun;163(6):1429-1438
Berberine exerts antioxidant effects via protection of spiral ganglion cells against cytomegalovirus-induced apoptosis.
Zhuang W, Li T, Wang C, Shi X, Li Y, Zhang S, Zhao Z, Dong H, Qiao Y
Free radical biology & medicine 2018 Jun;121:127-135
Free radical biology & medicine 2018 Jun;121:127-135
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Zhang J, Tucker LD, DongYan, Lu Y, Yang L, Wu C, Li Y, Zhang Q
Neurochemistry international 2018 Jun;116:1-12
Neurochemistry international 2018 Jun;116:1-12
Enhancer of zeste homolog 2 promotes cisplatin resistance by reducing cellular platinum accumulation.
Sun S, Zhao S, Yang Q, Wang W, Cai E, Wen Y, Yu L, Wang Z, Cai J
Cancer science 2018 Jun;109(6):1853-1864
Cancer science 2018 Jun;109(6):1853-1864
Acetylation of oxidized base repair-initiating NEIL1 DNA glycosylase required for chromatin-bound repair complex formation in the human genome increases cellular resistance to oxidative stress.
Sengupta S, Yang C, Hegde ML, Hegde PM, Mitra J, Pandey A, Dutta A, Datarwala AT, Bhakat KK, Mitra S
DNA repair 2018 Jun-Jul;66-67:1-10
DNA repair 2018 Jun-Jul;66-67:1-10
Mussel adhesive protein fused with VE-cadherin domain specifically triggers endothelial cell adhesion.
Yang D, Qiu J, Xu N, Zhao Y, Li T, Ma Q, Huang J, Wang G
Journal of materials chemistry. B 2018 Jun 28;6(24):4151-4163
Journal of materials chemistry. B 2018 Jun 28;6(24):4151-4163
Procyanidin B2 mitigates behavioral impairment and protects myelin integrity in cuprizone-induced schizophrenia in mice.
Tian H, Sun W, Zhang Q, Li X, Sang Y, Li J, Niu Y, Ding H
RSC advances 2018 Jun 27;8(42):23835-23846
RSC advances 2018 Jun 27;8(42):23835-23846
Effects of Levonorgestrel and progesterone on Oviductal physiology in mammals.
Li C, Zhang HY, Liang Y, Xia W, Zhu Q, Zhang D, Huang Z, Liang GL, Xue RH, Qi H, He XQ, Yuan JJ, Tan YJ, Huang HF, Zhang J
Reproductive biology and endocrinology : RB&E 2018 Jun 20;16(1):59
Reproductive biology and endocrinology : RB&E 2018 Jun 20;16(1):59
Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.
Fan L, Lu Y, Shen X, Shao H, Suo L, Wu Q
eLife 2018 Jun 18;7
eLife 2018 Jun 18;7
DRm217 attenuates myocardial ischemia-reperfusion injury via stabilizing plasma membrane Na(+)-K(+)-ATPase, inhibiting Na(+)-K(+)-ATPase/ROS pathway and activating PI3K/Akt and ERK1/2.
Yan X, Xun M, Wu L, Du X, Zhang F, Zheng J
Toxicology and applied pharmacology 2018 Jun 15;349:62-71
Toxicology and applied pharmacology 2018 Jun 15;349:62-71
Long noncoding RNA lncARSR promotes hepatic cholesterol biosynthesis via modulating Akt/SREBP-2/HMGCR pathway.
Huang J, Chen S, Cai D, Bian D, Wang F
Life sciences 2018 Jun 15;203:48-53
Life sciences 2018 Jun 15;203:48-53
Underexpression of Receptor for Activated C Kinase 1 (RACK1) in Leukocytes from Patients with Severe Acute Pancreatitis.
Zhang X, Guo J, Wang H, Zhang C, Shi N, Cai W, Jin T, Lin Z, Ma Y, Yang X, Xia Q, Xue P
The Tohoku journal of experimental medicine 2018 Jul;245(3):205-215
The Tohoku journal of experimental medicine 2018 Jul;245(3):205-215
Generation and propagation of yeast prion [URE3] are elevated under electromagnetic field.
Lian HY, Lin KW, Yang C, Cai P
Cell stress & chaperones 2018 Jul;23(4):581-594
Cell stress & chaperones 2018 Jul;23(4):581-594
Japanese encephalitis virus induces apoptosis by inhibiting Foxo signaling pathway.
Guo F, Yu X, Xu A, Xu J, Wang Q, Guo Y, Wu X, Tang Y, Ding Z, Zhang Y, Gong T, Pan Z, Li S, Kong L
Veterinary microbiology 2018 Jul;220:73-82
Veterinary microbiology 2018 Jul;220:73-82
Membrane topology of rat sodium-coupled neutral amino acid transporter 2 (SNAT2).
Ge Y, Gu Y, Wang J, Zhang Z
Biochimica et biophysica acta. Biomembranes 2018 Jul;1860(7):1460-1469
Biochimica et biophysica acta. Biomembranes 2018 Jul;1860(7):1460-1469
Rapamycin and ZSTK474 can have differential effects at different post‑infection time‑points regarding CVB3 replication and CVB3‑induced autophagy.
Chang H, Tian L, Chen J, Tang A, Li C, Li Z, Yang Z
Molecular medicine reports 2018 Jul;18(1):1088-1094
Molecular medicine reports 2018 Jul;18(1):1088-1094
Chronic stress causes protein kinase C epsilon-aldehyde dehydrogenase 2 signaling pathway perturbation in the rat hippocampus and prefrontal cortex, but not in the myocardium.
Zhang WY, Wang KY, Li YJ, Li YR, Lu RZ
Neural regeneration research 2018 Jul;13(7):1225-1230
Neural regeneration research 2018 Jul;13(7):1225-1230
A Polysaccharide Isolated from Dictyophora indusiata Promotes Recovery from Antibiotic-Driven Intestinal Dysbiosis and Improves Gut Epithelial Barrier Function in a Mouse Model.
Kanwal S, Joseph TP, Owusu L, Xiaomeng R, Meiqi L, Yi X
Nutrients 2018 Jul 31;10(8)
Nutrients 2018 Jul 31;10(8)
The actin cytoskeletal architecture of estrogen receptor positive breast cancer cells suppresses invasion.
Padilla-Rodriguez M, Parker SS, Adams DG, Westerling T, Puleo JI, Watson AW, Hill SM, Noon M, Gaudin R, Aaron J, Tong D, Roe DJ, Knudsen B, Mouneimne G
Nature communications 2018 Jul 30;9(1):2980
Nature communications 2018 Jul 30;9(1):2980
Myc activity is required for maintenance of the neuromesodermal progenitor signalling network and for segmentation clock gene oscillations in mouse.
Mastromina I, Verrier L, Silva JC, Storey KG, Dale JK
Development (Cambridge, England) 2018 Jul 30;145(14)
Development (Cambridge, England) 2018 Jul 30;145(14)
Synthesis and structure-activity relationship studies of MI-2 analogues as MALT1 inhibitors.
Wu G, Wang H, Zhou W, Zeng B, Mo W, Zhu K, Liu R, Zhou J, Chen C, Chen H
Bioorganic & medicinal chemistry 2018 Jul 23;26(12):3321-3344
Bioorganic & medicinal chemistry 2018 Jul 23;26(12):3321-3344
Blocking the Thiol at Cysteine-322 Destabilizes Tau Protein and Prevents Its Oligomer Formation.
Chen H, Liu S, Li S, Chen J, Ni J, Liu Q
ACS chemical neuroscience 2018 Jul 18;9(7):1560-1565
ACS chemical neuroscience 2018 Jul 18;9(7):1560-1565
ATXN3 Positively Regulates Type I IFN Antiviral Response by Deubiquitinating and Stabilizing HDAC3.
Feng Q, Miao Y, Ge J, Yuan Y, Zuo Y, Qian L, Liu J, Cheng Q, Guo T, Zhang L, Yu Z, Zheng H
Journal of immunology (Baltimore, Md. : 1950) 2018 Jul 15;201(2):675-687
Journal of immunology (Baltimore, Md. : 1950) 2018 Jul 15;201(2):675-687
Vitamin C increases 5-hydroxymethylcytosine level and inhibits the growth of bladder cancer.
Peng D, Ge G, Gong Y, Zhan Y, He S, Guan B, Li Y, Xu Z, Hao H, He Z, Xiong G, Zhang C, Shi Y, Zhou Y, Ci W, Li X, Zhou L
Clinical epigenetics 2018 Jul 13;10(1):94
Clinical epigenetics 2018 Jul 13;10(1):94
A novel small-molecule activator of Sirtuin-1 induces autophagic cell death/mitophagy as a potential therapeutic strategy in glioblastoma.
Yao ZQ, Zhang X, Zhen Y, He XY, Zhao S, Li XF, Yang B, Gao F, Guo FY, Fu L, Liu XZ, Duan CZ
Cell death & disease 2018 Jul 10;9(7):767
Cell death & disease 2018 Jul 10;9(7):767
A reproducible swine model of proximal descending thoracic aortic aneurysm created with intra-adventitial application of elastase.
Tian Y, Zhang W, Sun J, Zhai H, Yu Y, Qi X, Jones JA, Zhong H
Journal of vascular surgery 2018 Jan;67(1):300-308.e2
Journal of vascular surgery 2018 Jan;67(1):300-308.e2
Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.
Yang L, Tucker D, Dong Y, Wu C, Lu Y, Li Y, Zhang J, Liu TC, Zhang Q
Experimental neurology 2018 Jan;299(Pt A):86-96
Experimental neurology 2018 Jan;299(Pt A):86-96
Hypoxia induces the dysfunction of human endothelial colony-forming cells via HIF-1α signaling.
He M, Ma S, Cai Q, Wu Y, Shao C, Kong H, Wang H, Zeng X, Xie W
Respiratory physiology & neurobiology 2018 Jan;247:87-95
Respiratory physiology & neurobiology 2018 Jan;247:87-95
Mechanism of prolactin inhibition of miR-135b via methylation in goat mammary epithelial cells.
Chen Z, Luo J, Zhang C, Ma Y, Sun S, Zhang T, Loor JJ
Journal of cellular physiology 2018 Jan;233(1):651-662
Journal of cellular physiology 2018 Jan;233(1):651-662
Selectivity, cell permeability and oral availability studies of novel bromophenol derivative HPN as protein tyrosine phosphatase 1B inhibitor.
Luo J, Xu Q, Jiang B, Zhang R, Jia X, Li X, Wang L, Guo C, Wu N, Shi D
British journal of pharmacology 2018 Jan;175(1):140-153
British journal of pharmacology 2018 Jan;175(1):140-153
Clinical efficacy of recombinant human latrophilin 3 antibody in the treatment of pediatric asthma.
Liu M, Zhang J, Liu C
Experimental and therapeutic medicine 2018 Jan;15(1):539-547
Experimental and therapeutic medicine 2018 Jan;15(1):539-547
PTEN-L promotes type I interferon responses and antiviral immunity.
Cao Y, Wang H, Yang L, Zhang Z, Li C, Yuan X, Bu L, Chen L, Chen Y, Li CM, Guo D
Cellular & molecular immunology 2018 Jan;15(1):48-57
Cellular & molecular immunology 2018 Jan;15(1):48-57
Epithelial-mesenchymal crosstalk induces radioresistance in HNSCC cells.
Steinbichler TB, Alshaimaa A, Maria MV, Daniel D, Herbert R, Jozsef D, Ira-Ida S
Oncotarget 2018 Jan 9;9(3):3641-3652
Oncotarget 2018 Jan 9;9(3):3641-3652
Wnt/β-catenin pathway promotes acute lung injury induced by LPS through driving the Th17 response in mice.
Cheng L, Zhao Y, Qi D, Li W, Wang D
Biochemical and biophysical research communications 2018 Jan 8;495(2):1890-1895
Biochemical and biophysical research communications 2018 Jan 8;495(2):1890-1895
Comparative Proteomics Analysis Identifies Cdc42-Cdc42BPA Signaling as Prognostic Biomarker and Therapeutic Target for Colon Cancer Invasion.
Hu HF, Xu WW, Wang Y, Zheng CC, Zhang WX, Li B, He QY
Journal of proteome research 2018 Jan 5;17(1):265-275
Journal of proteome research 2018 Jan 5;17(1):265-275
Rhubarb Supplementation Promotes Intestinal Mucosal Innate Immune Homeostasis through Modulating Intestinal Epithelial Microbiota in Goat Kids.
Jiao J, Wu J, Wang M, Zhou C, Zhong R, Tan Z
Journal of agricultural and food chemistry 2018 Jan 31;66(4):1047-1057
Journal of agricultural and food chemistry 2018 Jan 31;66(4):1047-1057
Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
Zhou P, Liang Y, Zhang H, Jiang H, Feng K, Xu P, Wang J, Wang X, Ding K, Luo C, Liu M, Wang Y
European journal of medicinal chemistry 2018 Jan 20;144:817-842
European journal of medicinal chemistry 2018 Jan 20;144:817-842
SOCE induced calcium overload regulates autophagy in acute pancreatitis via calcineurin activation.
Zhu ZD, Yu T, Liu HJ, Jin J, He J
Cell death & disease 2018 Jan 19;9(2):50
Cell death & disease 2018 Jan 19;9(2):50
Autophagy promotes metastasis and glycolysis by upregulating MCT1 expression and Wnt/β-catenin signaling pathway activation in hepatocellular carcinoma cells.
Fan Q, Yang L, Zhang X, Ma Y, Li Y, Dong L, Zong Z, Hua X, Su D, Li H, Liu J
Journal of experimental & clinical cancer research : CR 2018 Jan 19;37(1):9
Journal of experimental & clinical cancer research : CR 2018 Jan 19;37(1):9
Increased Expression of Cullin 3 in Nasopharyngeal Carcinoma and Knockdown Inhibits Proliferation and Invasion.
Zeng R, Tan G, Li W, Ma Y
Oncology research 2018 Jan 19;26(1):111-122
Oncology research 2018 Jan 19;26(1):111-122
Proteasome Inhibitor Carbobenzoxy-L-Leucyl-L-Leucyl-L-Leucinal (MG132) Enhances Therapeutic Effect of Paclitaxel on Breast Cancer by Inhibiting Nuclear Factor (NF)-κB Signaling.
Zhang Y, Yang B, Zhao J, Li X, Zhang L, Zhai Z
Medical science monitor : international medical journal of experimental and clinical research 2018 Jan 15;24:294-304
Medical science monitor : international medical journal of experimental and clinical research 2018 Jan 15;24:294-304
miR-3189-3p Mimics Enhance the Effects of S100A4 siRNA on the Inhibition of Proliferation and Migration of Gastric Cancer Cells by Targeting CFL2.
Bian Y, Guo J, Qiao L, Sun X
International journal of molecular sciences 2018 Jan 13;19(1)
International journal of molecular sciences 2018 Jan 13;19(1)
Uncovering the anticancer mechanism of Compound Kushen Injection against HCC by integrating quantitative analysis, network analysis and experimental validation.
Gao L, Wang KX, Zhou YZ, Fang JS, Qin XM, Du GH
Scientific reports 2018 Jan 12;8(1):624
Scientific reports 2018 Jan 12;8(1):624
Dietary Supplement of Large Yellow Tea Ameliorates Metabolic Syndrome and Attenuates Hepatic Steatosis in db/db Mice.
Teng Y, Li D, Guruvaiah P, Xu N, Xie Z
Nutrients 2018 Jan 12;10(1)
Nutrients 2018 Jan 12;10(1)
Repulsive guidance molecule a suppresses angiogenesis after ischemia/reperfusion injury of middle cerebral artery occlusion in rats.
Wang Y, Zhang R, Xing X, Guo J, Xie F, Zhang G, Qin X
Neuroscience letters 2018 Jan 1;662:318-323
Neuroscience letters 2018 Jan 1;662:318-323
Protein Kinase A/CREB Signaling Prevents Adriamycin-Induced Podocyte Apoptosis via Upregulation of Mitochondrial Respiratory Chain Complexes.
Xie K, Zhu M, Xiang P, Chen X, Kasimumali A, Lu R, Wang Q, Mou S, Ni Z, Gu L, Pang H
Molecular and cellular biology 2018 Jan 1;38(1)
Molecular and cellular biology 2018 Jan 1;38(1)
Eukaryotic translation initiation factor 2 subunit α (eIF2α) inhibitor salubrinal attenuates paraquat-induced human lung epithelial-like A549 cell apoptosis by regulating the PERK-eIF2α signaling pathway.
Wang R, Sun DZ, Song CQ, Xu YM, Liu W, Liu Z, Dong XS
Toxicology in vitro : an international journal published in association with BIBRA 2018 Feb;46:58-65
Toxicology in vitro : an international journal published in association with BIBRA 2018 Feb;46:58-65
RhPDCD5 combined with dexamethasone increases antitumor activity in multiple myeloma partially via inhibiting the Wnt signalling pathway.
Cheng Q, Liu L, Fu Y, Zhang Y, Yang Y, Liu J
Clinical and experimental pharmacology & physiology 2018 Feb;45(2):140-145
Clinical and experimental pharmacology & physiology 2018 Feb;45(2):140-145
Aberrant expression of miR-451a contributes to 1,2-dichloroethane-induced hepatic glycerol gluconeogenesis disorder by inhibiting glycerol kinase expression in NIH Swiss mice.
Zeng N, Jiang H, Fan Q, Wang T, Rong W, Li G, Li R, Xu D, Guo T, Wang F, Zeng L, Huang M, Zheng J, Lu F, Chen W, Hu Q, Huang Z, Wang Q
Journal of applied toxicology : JAT 2018 Feb;38(2):292-303
Journal of applied toxicology : JAT 2018 Feb;38(2):292-303
Ephrin receptor A2 is an epithelial cell receptor for Epstein-Barr virus entry.
Zhang H, Li Y, Wang HB, Zhang A, Chen ML, Fang ZX, Dong XD, Li SB, Du Y, Xiong D, He JY, Li MZ, Liu YM, Zhou AJ, Zhong Q, Zeng YX, Kieff E, Zhang Z, Gewurz BE, Zhao B, Zeng MS
Nature microbiology 2018 Feb;3(2):1-8
Nature microbiology 2018 Feb;3(2):1-8
Carnosol-mediated Sirtuin 1 activation inhibits Enhancer of Zeste Homolog 2 to attenuate liver fibrosis.
Zhao H, Wang Z, Tang F, Zhao Y, Feng D, Li Y, Hu Y, Wang C, Zhou J, Tian X, Yao J
Pharmacological research 2018 Feb;128:327-337
Pharmacological research 2018 Feb;128:327-337
N-oleoylethanolamide suppresses intimal hyperplasia after balloon injury in rats through AMPK/PPARα pathway.
Zhao Y, Liu Y, Jing Z, Peng L, Jin P, Lin Y, Zhou Y, Yang L, Ren J, Xie Q, Jin X
Biochemical and biophysical research communications 2018 Feb 5;496(2):415-421
Biochemical and biophysical research communications 2018 Feb 5;496(2):415-421
PUM1 promotes ovarian cancer proliferation, migration and invasion.
Guan X, Chen S, Liu Y, Wang LL, Zhao Y, Zong ZH
Biochemical and biophysical research communications 2018 Feb 26;497(1):313-318
Biochemical and biophysical research communications 2018 Feb 26;497(1):313-318
Interferon-alpha enhances the antitumour activity of EGFR-targeted therapies by upregulating RIG-I in head and neck squamous cell carcinoma.
Ma H, Jin S, Yang W, Zhou G, Zhao M, Fang S, Zhang Z, Hu J
British journal of cancer 2018 Feb 20;118(4):509-521
British journal of cancer 2018 Feb 20;118(4):509-521
Involvement of impaired autophagy and mitophagy in Neuro-2a cell damage under hypoxic and/or high-glucose conditions.
Song Y, Du Y, Zou W, Luo Y, Zhang X, Fu J
Scientific reports 2018 Feb 19;8(1):3301
Scientific reports 2018 Feb 19;8(1):3301
Hypoxia Activates Src and Promotes Endocytosis Which Decreases MMP-2 Activity and Aggravates Renal Interstitial Fibrosis.
Cheng Z, Liu L, Wang Z, Cai Y, Xu Q, Chen P
International journal of molecular sciences 2018 Feb 15;19(2)
International journal of molecular sciences 2018 Feb 15;19(2)
The RARS-MAD1L1 Fusion Gene Induces Cancer Stem Cell-like Properties and Therapeutic Resistance in Nasopharyngeal Carcinoma.
Zhong Q, Liu ZH, Lin ZR, Hu ZD, Yuan L, Liu YM, Zhou AJ, Xu LH, Hu LJ, Wang ZF, Guan XY, Hao JJ, Lui VWY, Guo L, Mai HQ, Chen MY, Han F, Xia YF, Grandis JR, Zhang X, Zeng MS
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Feb 1;24(3):659-673
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Feb 1;24(3):659-673
Ajudecumin A from Ajuga ovalifolia var. calantha exhibits anti-inflammatory activity in lipopolysaccharide-activated RAW264.7 murine macrophages and animal models of acute inflammation.
Zhang H, Ren QC, Ren Y, Zhao L, Yang F, Zhang Y, Zhao WJ, Tan YZ, Shen XF
Pharmaceutical biology 2018 Dec;56(1):649-657
Pharmaceutical biology 2018 Dec;56(1):649-657
Effects of garlic polysaccharide on alcoholic liver fibrosis and intestinal microflora in mice.
Wang Y, Guan M, Zhao X, Li X
Pharmaceutical biology 2018 Dec;56(1):325-332
Pharmaceutical biology 2018 Dec;56(1):325-332
Involvement of PINK1/Parkin-mediated mitophagy in paraquat- induced apoptosis in human lung epithelial-like A549 cells.
Sun DZ, Song CQ, Xu YM, Wang R, Liu W, Liu Z, Dong XS
Toxicology in vitro : an international journal published in association with BIBRA 2018 Dec;53:148-159
Toxicology in vitro : an international journal published in association with BIBRA 2018 Dec;53:148-159
Oxymatrine attenuates brain hypoxic-ischemic injury from apoptosis and oxidative stress: role of p-Akt/GSK3β/HO-1/Nrf-2 signaling pathway.
Ge XH, Shao L, Zhu GJ
Metabolic brain disease 2018 Dec;33(6):1869-1875
Metabolic brain disease 2018 Dec;33(6):1869-1875
RNF126 Quenches RNF168 Function in the DNA Damage Response.
Zhang L, Wang Z, Shi R, Zhu X, Zhou J, Peng B, Xu X
Genomics, proteomics & bioinformatics 2018 Dec;16(6):428-438
Genomics, proteomics & bioinformatics 2018 Dec;16(6):428-438
1,3-Dichloro-2-Propanol inhibits autophagy via P53/AMPK/mTOR pathway in HepG2 cells.
Cheng B, Lu J, Li T, Meng Z, Liu M, Sun M, Guan S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2018 Dec;122:143-150
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2018 Dec;122:143-150
Urea transport B gene induces melanoma B16 cell death via activation of p53 and mitochondrial apoptosis.
Liu L, Sun Y, Zhao Y, Wang Q, Guo H, Guo R, Liu Y, Fu S, Zhang L, Li Y, Meng Y
Cancer science 2018 Dec;109(12):3762-3773
Cancer science 2018 Dec;109(12):3762-3773
Type 3 innate lymphoid cell: a new player in liver fibrosis progression.
Wang S, Li J, Wu S, Cheng L, Shen Y, Ma W, She W, Yang C, Wang J, Jiang W
Clinical science (London, England : 1979) 2018 Dec 21;132(24):2565-2582
Clinical science (London, England : 1979) 2018 Dec 21;132(24):2565-2582
Long non-coding RNA BRE-AS1 represses non-small cell lung cancer cell growth and survival via up-regulating NR4A3.
Zhang M, Wu J, Zhong W, Zhao Z, Liu Z
Archives of biochemistry and biophysics 2018 Dec 15;660:53-63
Archives of biochemistry and biophysics 2018 Dec 15;660:53-63
Distinct autophagy-inducing abilities of similar-sized nanoparticles in cell culture and live C. elegans.
Wang Q, Zhou Y, Fu R, Zhu Y, Song B, Zhong Y, Wu S, Shi Y, Wu Y, Su Y, Zhang H, He Y
Nanoscale 2018 Dec 13;10(48):23059-23069
Nanoscale 2018 Dec 13;10(48):23059-23069
Protein A from orange-spotted grouper nervous necrosis virus triggers type I interferon production in fish cell.
Huang R, Zhou Q, Shi Y, Zhang J, He J, Xie J
Fish & shellfish immunology 2018 Aug;79:234-243
Fish & shellfish immunology 2018 Aug;79:234-243
Overcoming resistance to mitochondrial apoptosis by BZML-induced mitotic catastrophe is enhanced by inhibition of autophagy in A549/Taxol cells.
Bai Z, Gao M, Xu X, Zhang H, Xu J, Guan Q, Wang Q, Du J, Li Z, Zuo D, Zhang W, Wu Y
Cell proliferation 2018 Aug;51(4):e12450
Cell proliferation 2018 Aug;51(4):e12450
Osteoglycin-induced VEGF Inhibition Enhances T Lymphocytes Infiltrating in Colorectal Cancer.
Hu X, Li YQ, Li QG, Ma YL, Peng JJ, Cai SJ
EBioMedicine 2018 Aug;34:35-45
EBioMedicine 2018 Aug;34:35-45
Restoration of 5-hydroxymethylcytosine by ascorbate blocks kidney tumour growth.
Ge G, Peng D, Xu Z, Guan B, Xin Z, He Q, Zhou Y, Li X, Zhou L, Ci W
EMBO reports 2018 Aug;19(8)
EMBO reports 2018 Aug;19(8)
Matrine inhibits the proliferation and migration of lung cancer cells through regulation of the protein kinase B/glycogen synthase kinase-3β signaling pathways.
Xie W, Lu J, Lu Q, Wang X, Long H, Huang J, Guo Z
Experimental and therapeutic medicine 2018 Aug;16(2):723-729
Experimental and therapeutic medicine 2018 Aug;16(2):723-729
TNFSF14/LIGHT, a Non-Canonical NF-κB Stimulus, Induces the HIF Pathway.
D'Ignazio L, Batie M, Rocha S
Cells 2018 Aug 8;7(8)
Cells 2018 Aug 8;7(8)
miR-346 Promotes HCC Progression by Suppressing Breast Cancer Metastasis Suppressor 1 Expression.
Guo Z, Li J, Sun J, Sun L, Zhou Y, Yu Z
Oncology research 2018 Aug 23;26(7):1073-1081
Oncology research 2018 Aug 23;26(7):1073-1081
NRAGE confers poor prognosis and promotes proliferation, invasion, and chemoresistance in gastric cancer.
Jiang X, Jiang X, Yang Z
Gene 2018 Aug 20;668:114-120
Gene 2018 Aug 20;668:114-120
Selenium-enriched yeast inhibited β-amyloid production and modulated autophagy in a triple transgenic mouse model of Alzheimer's disease.
Song GL, Chen C, Wu QY, Zhang ZH, Zheng R, Chen Y, Jia SZ, Ni JZ
Metallomics : integrated biometal science 2018 Aug 15;10(8):1107-1115
Metallomics : integrated biometal science 2018 Aug 15;10(8):1107-1115
Effects of Dahuang zhechong pill on doxorubicin-resistant SMMC-7721 xenografts in mice.
Wu L, Cao KX, Ni ZH, Li WD, Chen ZP, Cheng HB, Liu X
Journal of ethnopharmacology 2018 Aug 10;222:71-78
Journal of ethnopharmacology 2018 Aug 10;222:71-78
Uncoupling protein 1 expression in adipocytes derived from skeletal muscle fibro/adipogenic progenitors is under genetic and hormonal control.
Gorski T, Mathes S, Krützfeldt J
Journal of cachexia, sarcopenia and muscle 2018 Apr;9(2):384-399
Journal of cachexia, sarcopenia and muscle 2018 Apr;9(2):384-399
Role of TGF-β activated kinase-1 inhibitor on the interaction between macrophages and mesangial cells on the condition of high glucose.
Fan Z, Xu X, Qi X, Wu Y
Immunological investigations 2018 Apr;47(3):303-314
Immunological investigations 2018 Apr;47(3):303-314
MiR-151a is involved in the pathogenesis of atopic dermatitis by regulating interleukin-12 receptor β2.
Chen XF, Zhang LJ, Zhang J, Dou X, Shao Y, Jia XJ, Zhang W, Yu B
Experimental dermatology 2018 Apr;27(4):427-432
Experimental dermatology 2018 Apr;27(4):427-432
TIPE2 is negatively correlated with tissue factor and thrombospondin-1 expression in patients with bronchial asthma.
Shi G, Zhao JW, Sun XX, Ma JF, Wang P, He FC, Ming L
Experimental and therapeutic medicine 2018 Apr;15(4):3449-3454
Experimental and therapeutic medicine 2018 Apr;15(4):3449-3454
The enhancement of siPLK1 penetration across BBB and its anti glioblastoma activity in vivo by magnet and transferrin co-modified nanoparticle.
Liu DZ, Cheng Y, Cai RQ, Wang Bd WW, Cui H, Liu M, Zhang BL, Mei QB, Zhou SY
Nanomedicine : nanotechnology, biology, and medicine 2018 Apr;14(3):991-1003
Nanomedicine : nanotechnology, biology, and medicine 2018 Apr;14(3):991-1003
Identification of novel Nrf2 activators from Cinnamomum chartophyllum H.W. Li and their potential application of preventing oxidative insults in human lung epithelial cells.
Zhou MX, Li GH, Sun B, Xu YW, Li AL, Li YR, Ren DM, Wang XN, Wen XS, Lou HX, Shen T
Redox biology 2018 Apr;14:154-163
Redox biology 2018 Apr;14:154-163
Catalpol ameliorates hepatic insulin resistance in type 2 diabetes through acting on AMPK/NOX4/PI3K/AKT pathway.
Yan J, Wang C, Jin Y, Meng Q, Liu Q, Liu Z, Liu K, Sun H
Pharmacological research 2018 Apr;130:466-480
Pharmacological research 2018 Apr;130:466-480
Protective effect of methylallyl sulfone in the development of cigarette smoke extract-induced apoptosis in rats and HFL-1 cells.
Li A, Liu Y, Zhu X, Sun X, Feng X, Li D, Zhang J, Zhu M, Zhao Z
Biochemical and biophysical research communications 2018 Apr 6;498(3):627-632
Biochemical and biophysical research communications 2018 Apr 6;498(3):627-632
Smurf1 restricts the antiviral function mediated by USP25 through promoting its ubiquitination and degradation.
Qian G, Hu X, Li G, Ding Y, Zhu L, Zheng H, Li M, Li Z, Pan J, Li Y, Li G, Yang C, Liu Y, Xie Y, Lv H
Biochemical and biophysical research communications 2018 Apr 6;498(3):537-543
Biochemical and biophysical research communications 2018 Apr 6;498(3):537-543
GRASP55 Senses Glucose Deprivation through O-GlcNAcylation to Promote Autophagosome-Lysosome Fusion.
Zhang X, Wang L, Lak B, Li J, Jokitalo E, Wang Y
Developmental cell 2018 Apr 23;45(2):245-261.e6
Developmental cell 2018 Apr 23;45(2):245-261.e6
Pathological Features of Staphylococcus aureus Induced Mastitis in Dairy Cows and Isobaric-Tags-for-Relative-and-Absolute-Quantitation Proteomic Analyses.
Chen Z, Xia H, Shen H, Xu X, Arbab AAI, Li M, Zhang H, Mao Y, Yang Z
Journal of agricultural and food chemistry 2018 Apr 18;66(15):3880-3890
Journal of agricultural and food chemistry 2018 Apr 18;66(15):3880-3890
Role of silent information regulator 1 in the protective effect of hydrogen sulfide on homocysteine-induced cognitive dysfunction: Involving reduction of hippocampal ER stress.
Tang YY, Wang AP, Wei HJ, Li MH, Zou W, Li X, Wang CY, Zhang P, Tang XQ
Behavioural brain research 2018 Apr 16;342:35-42
Behavioural brain research 2018 Apr 16;342:35-42
Differential CRABP-II and FABP5 expression patterns and implications for medulloblastoma retinoic acid sensitivity.
Zhang S, Liu H, Li H, Wu M, Yu Y, Li F, Cheng X
RSC advances 2018 Apr 11;8(25):14048-14055
RSC advances 2018 Apr 11;8(25):14048-14055
Nogo-B receptor promotes epithelial-mesenchymal transition in non-small cell lung cancer cells through the Ras/ERK/Snail1 pathway.
Wu D, Zhao B, Qi X, Peng F, Fu H, Chi X, Miao QR, Shao S
Cancer letters 2018 Apr 1;418:135-146
Cancer letters 2018 Apr 1;418:135-146
GRHL2 suppresses tumor metastasis via regulation of transcriptional activity of RhoG in non-small cell lung cancer.
Pan X, Zhang R, Xie C, Gan M, Yao S, Yao Y, Jin J, Han T, Huang Y, Gong Y, Wang J, Yu B
American journal of translational research 2017;9(9):4217-4226
American journal of translational research 2017;9(9):4217-4226
Silencing Rab14 represses the proliferation and migration of oral squamous cell carcinoma, and enhances cisplatin sensitivity.
Lian Q, Ma DM, Chen MG, Chen K, Li XJ
American journal of translational research 2017;9(9):4195-4205
American journal of translational research 2017;9(9):4195-4205
3-Mercaptopyruvate Sulfurtransferase, Not Cystathionine β-Synthase Nor Cystathionine γ-Lyase, Mediates Hypoxia-Induced Migration of Vascular Endothelial Cells.
Tao B, Wang R, Sun C, Zhu Y
Frontiers in pharmacology 2017;8:657
Frontiers in pharmacology 2017;8:657
Antimycobacterial and Anti-inflammatory Mechanisms of Baicalin via Induced Autophagy in Macrophages Infected with Mycobacterium tuberculosis.
Zhang Q, Sun J, Wang Y, He W, Wang L, Zheng Y, Wu J, Zhang Y, Jiang X
Frontiers in microbiology 2017;8:2142
Frontiers in microbiology 2017;8:2142
Variant Amino Acid Residues Alter the Enzyme Activity of Peanut Type 2 Diacylglycerol Acyltransferases.
Zheng L, Shockey J, Bian F, Chen G, Shan L, Li X, Wan S, Peng Z
Frontiers in plant science 2017;8:1751
Frontiers in plant science 2017;8:1751
Iridoids with Genipin Stem Nucleus Inhibit Lipopolysaccharide-Induced Inflammation and Oxidative Stress by Blocking the NF-κB Pathway in Polycystic Ovary Syndrome.
Zuo T, Zhu M, Xu W, Wang Z, Song H
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(5):1855-1865
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(5):1855-1865
The USP7 Inhibitor P5091 Induces Cell Death in Ovarian Cancers with Different P53 Status.
Wang M, Zhang Y, Wang T, Zhang J, Zhou Z, Sun Y, Wang S, Shi Y, Luan X, Zhang Y, Wang Y, Wang Y, Zou Z, Kang L, Liu H
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(5):1755-1766
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(5):1755-1766
α-Lipoic Acid Promotes Neurological Recovery After Ischemic Stroke by Activating the Nrf2/HO-1 Pathway to Attenuate Oxidative Damage.
Lv C, Maharjan S, Wang Q, Sun Y, Han X, Wang S, Mao Z, Xin Y, Zhang B
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(3):1273-1287
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(3):1273-1287
Targeted kinase inhibition relieves slowness and tremor in a Drosophila model of LRRK2 Parkinson's disease.
Cording AC, Shiaelis N, Petridi S, Middleton CA, Wilson LG, Elliott CJH
NPJ Parkinson's disease 2017;3:34
NPJ Parkinson's disease 2017;3:34
Endoplasmic Reticulum Stress Is Involved in Cochlear Cell Apoptosis in a Cisplatin-Induced Ototoxicity Rat Model.
Zong S, Liu T, Wan F, Chen P, Luo P, Xiao H
Audiology & neuro-otology 2017;22(3):160-168
Audiology & neuro-otology 2017;22(3):160-168
Role of Zebrafish fhl1A in Satellite Cell and Skeletal Muscle Development.
Chen F, Yuan W, Mo X, Zhuang J, Wang Y, Chen J, Jiang Z, Zhu X, Zeng Q, Wan Y, Li F, Shi Y, Cao L, Fan X, Luo S, Ye X, Chen Y, Dai G, Gao J, Wang X, Xie H, Zhu P, Li Y, Wu X
Current molecular medicine 2017;17(9):627-636
Current molecular medicine 2017;17(9):627-636
XRCC5 cooperates with p300 to promote cyclooxygenase-2 expression and tumor growth in colon cancers.
Zhang Z, Zheng F, Yu Z, Hao J, Chen M, Yu W, Guo W, Chen Y, Huang W, Duan Z, Deng W
PloS one 2017;12(10):e0186900
PloS one 2017;12(10):e0186900
miR-125b-5p functions as a tumor suppressor gene partially by regulating HMGA2 in esophageal squamous cell carcinoma.
Mei LL, Wang WJ, Qiu YT, Xie XF, Bai J, Shi ZZ
PloS one 2017;12(10):e0185636
PloS one 2017;12(10):e0185636
Autophagy promotes degradation of polyethyleneimine-alginate nanoparticles in endothelial progenitor cells.
Wang GD, Tan YZ, Wang HJ, Zhou P
International journal of nanomedicine 2017;12:6661-6675
International journal of nanomedicine 2017;12:6661-6675
Curcumin Activates AMPK Pathway and Regulates Lipid Metabolism in Rats Following Prolonged Clozapine Exposure.
Liu Z, Cui C, Xu P, Dang R, Cai H, Liao D, Yang M, Feng Q, Yan X, Jiang P
Frontiers in neuroscience 2017;11:558
Frontiers in neuroscience 2017;11:558
Paeoniflorin attenuates incipient diabetic nephropathy in streptozotocin-induced mice by the suppression of the Toll-like receptor-2 signaling pathway.
Shao YX, Xu XX, Wang K, Qi XM, Wu YG
Drug design, development and therapy 2017;11:3221-3233
Drug design, development and therapy 2017;11:3221-3233
Roux-en-Y Gastric Bypass Improves Hepatic Glucose Metabolism Involving Down-Regulation of Protein Tyrosine Phosphatase 1B in Obese Rats.
Mu S, Liu J, Guo W, Zhang S, Xiao X, Wang Z, Zhang J
Obesity facts 2017;10(3):191-206
Obesity facts 2017;10(3):191-206
HOXD-AS1 functions as an oncogenic ceRNA to promote NSCLC cell progression by sequestering miR-147a.
Wang Q, Jiang S, Song A, Hou S, Wu Q, Qi L, Gao X
OncoTargets and therapy 2017;10:4753-4763
OncoTargets and therapy 2017;10:4753-4763
Transcription Factor NFAT5 Promotes Glioblastoma Cell-driven Angiogenesis via SBF2-AS1/miR-338-3p-Mediated EGFL7 Expression Change.
Yu H, Zheng J, Liu X, Xue Y, Shen S, Zhao L, Li Z, Liu Y
Frontiers in molecular neuroscience 2017;10:301
Frontiers in molecular neuroscience 2017;10:301
Identification of Flavin-Containing Monooxygenase 5 (FMO5) as a Regulator of Glucose Homeostasis and a Potential Sensor of Gut Bacteria.
Scott F, Gonzalez Malagon SG, O'Brien BA, Fennema D, Veeravalli S, Coveney CR, Phillips IR, Shephard EA
Drug metabolism and disposition: the biological fate of chemicals 2017 Sep;45(9):982-989
Drug metabolism and disposition: the biological fate of chemicals 2017 Sep;45(9):982-989
Visfatin induces the apoptosis of endothelial progenitor cells via the induction of pro-inflammatory mediators through the NF-κB pathway.
Sun L, Chen S, Gao H, Ren L, Song G
International journal of molecular medicine 2017 Sep;40(3):637-646
International journal of molecular medicine 2017 Sep;40(3):637-646
Mechanism of Lycium barbarum polysaccharides on primary cultured rat hippocampal neurons.
Zhao P, Ma NT, Chang RY, Li YX, Hao YJ, Yang WL, Zheng J, Niu Y, Sun T, Yu JQ
Cell and tissue research 2017 Sep;369(3):455-465
Cell and tissue research 2017 Sep;369(3):455-465
Downregulation of serum RAB27B confers improved prognosis and is associated with hepatocellular carcinoma progression through PI3K-AKT-P21 signaling.
Yang X, Ye X, Sun L, Gao F, Li Y, Ji X, Wang X, Feng Y, Wang X
Oncotarget 2017 Sep 22;8(37):61118-61132
Oncotarget 2017 Sep 22;8(37):61118-61132
Vegetally localised Vrtn functions as a novel repressor to modulate bmp2b transcription during dorsoventral patterning in zebrafish.
Shao M, Wang M, Liu YY, Ge YW, Zhang YJ, Shi DL
Development (Cambridge, England) 2017 Sep 15;144(18):3361-3374
Development (Cambridge, England) 2017 Sep 15;144(18):3361-3374
Dendrobium nobile Lindl. alkaloids regulate metabolism gene expression in livers of mice.
Xu YY, Xu YS, Wang Y, Wu Q, Lu YF, Liu J, Shi JS
The Journal of pharmacy and pharmacology 2017 Oct;69(10):1409-1417
The Journal of pharmacy and pharmacology 2017 Oct;69(10):1409-1417
APPL1 promotes the migration of gastric cancer cells by regulating Akt2 phosphorylation.
Liu Y, Zhang C, Zhao L, Du N, Hou N, Song T, Huang C
International journal of oncology 2017 Oct;51(4):1343-1351
International journal of oncology 2017 Oct;51(4):1343-1351
Thrombospondin-1 Production Regulates the Inflammatory Cytokine Secretion in THP-1 Cells Through NF-κB Signaling Pathway.
Xing T, Wang Y, Ding WJ, Li YL, Hu XD, Wang C, Ding A, Shen JL
Inflammation 2017 Oct;40(5):1606-1621
Inflammation 2017 Oct;40(5):1606-1621
An Important Function of Petrosiol E in Inducing the Differentiation of Neuronal Progenitors and in Protecting Them against Oxidative Stress.
Liu J, Wang L, Du Y, Liu S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2017 Oct;4(10):1700089
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2017 Oct;4(10):1700089
Anti-inflammatory capacity of Lactobacillus rhamnosus GG in monophasic variant Salmonella infected piglets is correlated with impeding NLRP6-mediated host inflammatory responses.
Yu J, Zhu YH, Yang GY, Zhang W, Zhou D, Su JH, Wang JF
Veterinary microbiology 2017 Oct;210:91-100
Veterinary microbiology 2017 Oct;210:91-100
Ovarian cancer proliferation and apoptosis are regulated by human transfer RNA methyltransferase 9-likevia LIN9.
Chen HM, Wang J, Zhang YF, Gao YH
Oncology letters 2017 Oct;14(4):4461-4466
Oncology letters 2017 Oct;14(4):4461-4466
High expression of IL-4R enhances proliferation and invasion of hepatocellular carcinoma cells.
Guo C, Ouyang Y, Cai J, Xiong L, Chen Y, Zeng X, Liu A
The International journal of biological markers 2017 Oct 31;32(4):e384-e390
The International journal of biological markers 2017 Oct 31;32(4):e384-e390
The role of long non-coding RNA PCA3 in epithelial ovarian carcinoma tumorigenesis and progression.
Liu Y, Zong ZH, Guan X, Wang LL, Zhao Y
Gene 2017 Oct 30;633:42-47
Gene 2017 Oct 30;633:42-47
Inhibition of Starvation-Triggered Endoplasmic Reticulum Stress, Autophagy, and Apoptosis in ARPE-19 Cells by Taurine through Modulating the Expression of Calpain-1 and Calpain-2.
Zhang Y, Ren S, Liu Y, Gao K, Liu Z, Zhang Z
International journal of molecular sciences 2017 Oct 14;18(10)
International journal of molecular sciences 2017 Oct 14;18(10)
Evidence for a direct cross-talk between malic enzyme and the pentose phosphate pathway via structural interactions.
Yao P, Sun H, Xu C, Chen T, Zou B, Jiang P, Du W
The Journal of biological chemistry 2017 Oct 13;292(41):17113-17120
The Journal of biological chemistry 2017 Oct 13;292(41):17113-17120
Ligand-dependent EphA7 signaling inhibits prostate tumor growth and progression.
Li S, Wu Z, Ma P, Xu Y, Chen Y, Wang H, He P, Kang Z, Yin L, Zhao Y, Zhang X, Xu X, Ma X, Guan M
Cell death & disease 2017 Oct 12;8(10):e3122
Cell death & disease 2017 Oct 12;8(10):e3122
Fluoride-Induced Autophagy via the Regulation of Phosphorylation of Mammalian Targets of Rapamycin in Mice Leydig Cells.
Zhang J, Zhu Y, Shi Y, Han Y, Liang C, Feng Z, Zheng H, Eng M, Wang J
Journal of agricultural and food chemistry 2017 Oct 11;65(40):8966-8976
Journal of agricultural and food chemistry 2017 Oct 11;65(40):8966-8976
MicroRNA-23a promotes pancreatic cancer metastasis by targeting epithelial splicing regulator protein 1.
Wu G, Li Z, Jiang P, Zhang X, Xu Y, Chen K, Li X
Oncotarget 2017 Oct 10;8(47):82854-82871
Oncotarget 2017 Oct 10;8(47):82854-82871
Epigenetic silencing of ASPP1 confers 5-FU resistance in clear cell renal cell carcinoma by preventing p53 activation.
Wang X, Cheng Y, Zhu Y, Li H, Ge W, Wu X, Zhao K, Yuan J, Li Z, Jiang S, Han Z, Jiang Q, Wu Q, Liu T, Zhang C, Yu M, Hu Y
International journal of cancer 2017 Oct 1;141(7):1422-1433
International journal of cancer 2017 Oct 1;141(7):1422-1433
Cryptotanshinone sensitizes antitumor effect of paclitaxel on tongue squamous cell carcinoma growth by inhibiting the JAK/STAT3 signaling pathway.
Wang Y, Lu HL, Liu YD, Yang LY, Jiang QK, Zhu XJ, Fan HN, Qian Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Nov;95:1388-1396
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Nov;95:1388-1396
Spatiotemporal Expression of Bcl-2/Bax and Neural Cell Apoptosis in the Developing Lumbosacral Spinal Cord of Rat Fetuses with Anorectal Malformations.
Yang Z, Geng Y, Yao Z, Jia H, Bai Y, Wang W
Neurochemical research 2017 Nov;42(11):3160-3169
Neurochemical research 2017 Nov;42(11):3160-3169
Sialic acid-modified solid lipid nanoparticles as vascular endothelium-targeting carriers for ischemia-reperfusion-induced acute renal injury.
Hu JB, Song GL, Liu D, Li SJ, Wu JH, Kang XQ, Qi J, Jin FY, Wang XJ, Xu XL, Ying XY, Yu L, You J, Du YZ
Drug delivery 2017 Nov;24(1):1856-1867
Drug delivery 2017 Nov;24(1):1856-1867
Lack of BACE1 S-palmitoylation reduces amyloid burden and mitigates memory deficits in transgenic mouse models of Alzheimer's disease.
Andrew RJ, Fernandez CG, Stanley M, Jiang H, Nguyen P, Rice RC, Buggia-Prévot V, De Rossi P, Vetrivel KS, Lamb R, Argemi A, Allaert ES, Rathbun EM, Krause SV, Wagner SL, Parent AT, Holtzman DM, Thinakaran G
Proceedings of the National Academy of Sciences of the United States of America 2017 Nov 7;114(45):E9665-E9674
Proceedings of the National Academy of Sciences of the United States of America 2017 Nov 7;114(45):E9665-E9674
Cell-autonomous adiposity through increased cell surface GLUT4 due to ankyrin-B deficiency.
Lorenzo DN, Bennett V
Proceedings of the National Academy of Sciences of the United States of America 2017 Nov 28;114(48):12743-12748
Proceedings of the National Academy of Sciences of the United States of America 2017 Nov 28;114(48):12743-12748
Proteomics and metabolomics analysis of hepatic mitochondrial metabolism in alcohol-preferring and non-preferring rats.
Zeng HL, Yang Q, Du H, Li H, Shen Y, Liu T, Chen X, Kamal GM, Guan Q, Cheng L, Wang J, Xu F
Oncotarget 2017 Nov 24;8(60):102020-102032
Oncotarget 2017 Nov 24;8(60):102020-102032
Copper or/and arsenic induce oxidative stress-cascaded, nuclear factor kappa B-dependent inflammation and immune imbalance, trigging heat shock response in the kidney of chicken.
Wang Y, Zhao H, Shao Y, Liu J, Li J, Xing M
Oncotarget 2017 Nov 17;8(58):98103-98116
Oncotarget 2017 Nov 17;8(58):98103-98116
Hydrogen Sulfide Inhibits Chronic Unpredictable Mild Stress-Induced Depressive-Like Behavior by Upregulation of Sirt-1: Involvement in Suppression of Hippocampal Endoplasmic Reticulum Stress.
Liu SY, Li D, Zeng HY, Kan LY, Zou W, Zhang P, Gu HF, Tang XQ
The international journal of neuropsychopharmacology 2017 Nov 1;20(11):867-876
The international journal of neuropsychopharmacology 2017 Nov 1;20(11):867-876
Inhibition of tissue transglutaminase attenuates lipopolysaccharide-induced inflammation in glial cells through AKT/mTOR signal pathway.
Ding Y, Zhang J, Wang R
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:1310-1319
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:1310-1319
FGF7/FGFR2 signal promotes invasion and migration in human gastric cancer through upregulation of thrombospondin-1.
Huang T, Wang L, Liu D, Li P, Xiong H, Zhuang L, Sun L, Yuan X, Qiu H
International journal of oncology 2017 May;50(5):1501-1512
International journal of oncology 2017 May;50(5):1501-1512
Embelin attenuates adipogenesis and lipogenesis through activating canonical Wnt signaling and inhibits high-fat diet-induced obesity.
Gao Y, Li J, Xu X, Wang S, Yang Y, Zhou J, Zhang L, Zheng F, Li X, Wang B
International journal of obesity (2005) 2017 May;41(5):729-738
International journal of obesity (2005) 2017 May;41(5):729-738
Preliminary evaluation for Bit1 as a potential biomarker for squamous cell carcinoma and adenocarcinoma of esophagus.
Chen J, Liu H, Gao P, Hui Y, Yang Z, Zhang X, Xu P, Tian F, Fan T
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 May;39(5):1010428317708267
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 May;39(5):1010428317708267
Sulforaphane-cysteine induces apoptosis by sustained activation of ERK1/2 and caspase 3 in human glioblastoma U373MG and U87MG cells.
Wu S, Zhou Y, Yang G, Tian H, Geng Y, Hu Y, Lin K, Wu W
Oncology reports 2017 May;37(5):2829-2838
Oncology reports 2017 May;37(5):2829-2838
oxLDL antibody inhibits MCP-1 release in monocytes/macrophages by regulating Ca(2+) /K(+) channel flow.
Su J, Zhou H, Liu X, Nilsson J, Fredrikson GN, Zhao M
Journal of cellular and molecular medicine 2017 May;21(5):929-940
Journal of cellular and molecular medicine 2017 May;21(5):929-940
TET3-mediated DNA oxidation promotes ATR-dependent DNA damage response.
Jiang D, Wei S, Chen F, Zhang Y, Li J
EMBO reports 2017 May;18(5):781-796
EMBO reports 2017 May;18(5):781-796
Menin enhances c-Myc-mediated transcription to promote cancer progression.
Wu G, Yuan M, Shen S, Ma X, Fang J, Zhu L, Sun L, Liu Z, He X, Huang D, Li T, Li C, Wu J, Hu X, Li Z, Song L, Qu K, Zhang H, Gao P
Nature communications 2017 May 5;8:15278
Nature communications 2017 May 5;8:15278
Thyroid stimulating hormone increases hepatic gluconeogenesis via CRTC2.
Li Y, Wang L, Zhou L, Song Y, Ma S, Yu C, Zhao J, Xu C, Gao L
Molecular and cellular endocrinology 2017 May 5;446:70-80
Molecular and cellular endocrinology 2017 May 5;446:70-80
Longikaurin A, a natural ent-kaurane, suppresses stemness in nasopharyngeal carcinoma cells.
Yuan Y, Du Y, Hu XY, Liu MY, Du JK, Liu XM, Yu HE, Wang TZ, Pu JX, Zhong Q, Zou QF
Oncology letters 2017 Mar;13(3):1672-1680
Oncology letters 2017 Mar;13(3):1672-1680
Hypoxia promotes chemotherapy resistance by down-regulating SKA1 gene expression in human osteosarcoma.
Ma Q, Zhang Y, Liu T, Jiang K, Wen Y, Fan Q, Qiu X
Cancer biology & therapy 2017 Mar 4;18(3):177-185
Cancer biology & therapy 2017 Mar 4;18(3):177-185
miR-148a and miR-17-5p synergistically regulate milk TAG synthesis via PPARGC1A and PPARA in goat mammary epithelial cells.
Chen Z, Luo J, Sun S, Cao D, Shi H, Loor JJ
RNA biology 2017 Mar 4;14(3):326-338
RNA biology 2017 Mar 4;14(3):326-338
MicroRNA-17-92 Regulates the Transcription Factor E2F3b during Myogenesis In Vitro and In Vivo.
Tang Z, Liu N, Luo L, Kang K, Li L, Ni R, Qiu H, Gou D
International journal of molecular sciences 2017 Mar 31;18(4)
International journal of molecular sciences 2017 Mar 31;18(4)
Probiotics may delay the progression of nonalcoholic fatty liver disease by restoring the gut microbiota structure and improving intestinal endotoxemia.
Xue L, He J, Gao N, Lu X, Li M, Wu X, Liu Z, Jin Y, Liu J, Xu J, Geng Y
Scientific reports 2017 Mar 28;7:45176
Scientific reports 2017 Mar 28;7:45176
Anti-tumor effect of evodiamine by inducing Akt-mediated apoptosis in hepatocellular carcinoma.
Yang F, Shi L, Liang T, Ji L, Zhang G, Shen Y, Zhu F, Xu L
Biochemical and biophysical research communications 2017 Mar 25;485(1):54-61
Biochemical and biophysical research communications 2017 Mar 25;485(1):54-61
AMPK/α-Ketoglutarate Axis Regulates Intestinal Water and Ion Homeostasis in Young Pigs.
He L, Huang N, Li H, Tian J, Zhou X, Li T, Yao K, Wu G, Yin Y
Journal of agricultural and food chemistry 2017 Mar 22;65(11):2287-2298
Journal of agricultural and food chemistry 2017 Mar 22;65(11):2287-2298
Upregulation of microRNA-574-3p in a human gastric cancer cell line AGS by TGF-β1.
Zhang R, Wang M, Sui P, Ding L, Yang Q
Gene 2017 Mar 20;605:63-69
Gene 2017 Mar 20;605:63-69
A coumarin-based fluorescence resonance energy transfer probe targeting matrix metalloproteinase-2 for the detection of cervical cancer.
He G, Yang L, Qian X, Li J, Yuan Z, Li C
International journal of molecular medicine 2017 Jun;39(6):1571-1579
International journal of molecular medicine 2017 Jun;39(6):1571-1579
Sulforaphane prevents bleomycin‑induced pulmonary fibrosis in mice by inhibiting oxidative stress via nuclear factor erythroid 2‑related factor‑2 activation.
Yan B, Ma Z, Shi S, Hu Y, Ma T, Rong G, Yang J
Molecular medicine reports 2017 Jun;15(6):4005-4014
Molecular medicine reports 2017 Jun;15(6):4005-4014
Cerebrolysin alleviates cognitive deficits induced by chronic cerebral hypoperfusion by increasing the levels of plasticity-related proteins and decreasing the levels of apoptosis-related proteins in the rat hippocampus.
Liu Z, Hu M, Lu P, Wang H, Qi Q, Xu J, Xiao Y, Fan M, Jia Y, Zhang D
Neuroscience letters 2017 Jun 9;651:72-78
Neuroscience letters 2017 Jun 9;651:72-78
CADASIL mutant NOTCH3(R90C) decreases the viability of HS683 oligodendrocytes via apoptosis.
Tang M, Shi C, Song B, Yang J, Yang T, Mao C, Li Y, Liu X, Zhang S, Wang H, Luo H, Xu Y
Molecular biology reports 2017 Jul;44(3):273-280
Molecular biology reports 2017 Jul;44(3):273-280
The MBNL3 splicing factor promotes hepatocellular carcinoma by increasing PXN expression through the alternative splicing of lncRNA-PXN-AS1.
Yuan JH, Liu XN, Wang TT, Pan W, Tao QF, Zhou WP, Wang F, Sun SH
Nature cell biology 2017 Jul;19(7):820-832
Nature cell biology 2017 Jul;19(7):820-832
Malvidin and cyanidin derivatives from açai fruit (Euterpe oleracea Mart.) counteract UV-A-induced oxidative stress in immortalized fibroblasts.
Petruk G, Illiano A, Del Giudice R, Raiola A, Amoresano A, Rigano MM, Piccoli R, Monti DM
Journal of photochemistry and photobiology. B, Biology 2017 Jul;172:42-51
Journal of photochemistry and photobiology. B, Biology 2017 Jul;172:42-51
Selenium-Containing Polysaccharide-Protein Complex in Se-Enriched Ulva fasciata Induces Mitochondria-Mediated Apoptosis in A549 Human Lung Cancer Cells.
Sun X, Zhong Y, Luo H, Yang Y
Marine drugs 2017 Jul 16;15(7)
Marine drugs 2017 Jul 16;15(7)
Deubiquitinase USP33 is negatively regulated by β-TrCP through ubiquitin-dependent proteolysis.
Cheng Q, Yuan Y, Li L, Guo T, Miao Y, Ren Y, Liu J, Feng Q, Wang X, Zhao P, Zuo Y, Qian L, Zhang L, Zheng H
Experimental cell research 2017 Jul 1;356(1):1-7
Experimental cell research 2017 Jul 1;356(1):1-7
Transcription regulator TRIP-Br2 mediates ER stress-induced brown adipocytes dysfunction.
Qiang G, Whang Kong H, Gil V, Liew CW
Scientific reports 2017 Jan 9;7:40215
Scientific reports 2017 Jan 9;7:40215
The role of the ATM/Chk/P53 pathway in mediating DNA damage in hand-foot syndrome induced by PLD.
Yang J, Qiao L, Zeng Z, Wang J, Zhu T, Wei J, Wu M, Ye S, Huang X, Ma D, Liu R, Gao Q
Toxicology letters 2017 Jan 4;265:131-139
Toxicology letters 2017 Jan 4;265:131-139
Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin.
Xue C, Wang C, Sun Y, Meng Q, Liu Z, Huo X, Sun P, Sun H, Ma X, Ma X, Peng J, Liu K
Oncotarget 2017 Jan 31;8(5):8622-8632
Oncotarget 2017 Jan 31;8(5):8622-8632
Knockdown of TREM-1 suppresses IL-1β-induced chondrocyte injury via inhibiting the NF-κB pathway.
Tang J, Dong Q
Biochemical and biophysical research communications 2017 Jan 22;482(4):1240-1245
Biochemical and biophysical research communications 2017 Jan 22;482(4):1240-1245
Transdifferentiation of human male germline stem cells to hepatocytes in vivo via the transplantation under renal capsules.
Chen Z, Niu M, Sun M, Yuan Q, Yao C, Hou J, Wang H, Wen L, Fu H, Zhou F, Li Z, He Z
Oncotarget 2017 Feb 28;8(9):14576-14592
Oncotarget 2017 Feb 28;8(9):14576-14592
Calycosin attenuates triglyceride accumulation and hepatic fibrosis in murine model of non-alcoholic steatohepatitis via activating farnesoid X receptor.
Duan X, Meng Q, Wang C, Liu Z, Liu Q, Sun H, Sun P, Yang X, Huo X, Peng J, Liu K
Phytomedicine : international journal of phytotherapy and phytopharmacology 2017 Feb 15;25:83-92
Phytomedicine : international journal of phytotherapy and phytopharmacology 2017 Feb 15;25:83-92
Single tumor-initiating cells evade immune clearance by recruiting type II macrophages.
Guo X, Zhao Y, Yan H, Yang Y, Shen S, Dai X, Ji X, Ji F, Gong XG, Li L, Bai X, Feng XH, Liang T, Ji J, Chen L, Wang H, Zhao B
Genes & development 2017 Feb 1;31(3):247-259
Genes & development 2017 Feb 1;31(3):247-259
Ontogeny, aging, and gender-related changes in hepatic multidrug resistant protein genes in rats.
Zhu QN, Hou WY, Xu SF, Lu YF, Liu J
Life sciences 2017 Feb 1;170:108-114
Life sciences 2017 Feb 1;170:108-114
Altered Expression of TXNIP in the peripheral leukocytes of patients with coronary atherosclerotic heart disease.
Zhang Y, Huang J, Yang X, Sun X, Xu Q, Wang B, Zhong P, Wei Z
Medicine 2017 Dec;96(49):e9108
Medicine 2017 Dec;96(49):e9108
Effects of polysaccharide from Physalis alkekengi var. francheti on liver injury and intestinal microflora in type-2 diabetic mice.
Zhao X, Chen Z, Yin Y, Li X
Pharmaceutical biology 2017 Dec;55(1):2020-2025
Pharmaceutical biology 2017 Dec;55(1):2020-2025
Induction of autophagy by an oleanolic acid derivative, SZC017, promotes ROS-dependent apoptosis through Akt and JAK2/STAT3 signaling pathway in human lung cancer cells.
Song Y, Kong L, Sun B, Gao L, Chu P, Ahsan A, Qaed E, Lin Y, Peng J, Ma X, Zhang J, Wang S, Tang Z
Cell biology international 2017 Dec;41(12):1367-1378
Cell biology international 2017 Dec;41(12):1367-1378
Glucose potentiates β-cell function by inducing Tph1 expression in rat islets.
Zhang Y, Deng R, Yang X, Xu W, Liu Y, Li F, Zhang J, Tang H, Ji X, Bi Y, Wang X, Zhou L, Ning G
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Dec;31(12):5342-5355
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Dec;31(12):5342-5355
POSH participates in epileptogenesis by increasing the surface expression of the NMDA receptor: a promising therapeutic target for epilepsy.
Wang X, Tian X, Yang Y, Lu X, Li Y, Ma Y, Zhang Y, Zheng F, Lu S, Xu D, Xu X, Wang W, Wang X
Expert opinion on therapeutic targets 2017 Dec;21(12):1083-1094
Expert opinion on therapeutic targets 2017 Dec;21(12):1083-1094
Regulation of AMH by oocyte-specific growth factors in human primary cumulus cells.
Convissar S, Armouti M, Fierro MA, Winston NJ, Scoccia H, Zamah AM, Stocco C
Reproduction (Cambridge, England) 2017 Dec;154(6):745-753
Reproduction (Cambridge, England) 2017 Dec;154(6):745-753
Effects of dimethyl carbonate-induced autophagic activation on follicular development in the mouse ovary.
Tang Z, Zhang Z, Tang Y, Qi L, Yang F, Wang Z
Experimental and therapeutic medicine 2017 Dec;14(6):5981-5989
Experimental and therapeutic medicine 2017 Dec;14(6):5981-5989
MicroRNA-30e Functions as a Tumor Suppressor in Cervical Carcinoma Cells through Targeting GALNT7.
Wu H, Chen J, Li D, Liu X, Li L, Wang K
Translational oncology 2017 Dec;10(6):876-885
Translational oncology 2017 Dec;10(6):876-885
Piperlongumine suppresses bladder cancer invasion via inhibiting epithelial mesenchymal transition and F-actin reorganization.
Liu D, Qiu XY, Wu X, Hu DX, Li CY, Yu SB, Pan F, Chen XQ
Biochemical and biophysical research communications 2017 Dec 9;494(1-2):165-172
Biochemical and biophysical research communications 2017 Dec 9;494(1-2):165-172
Salvianolic acid B protects against lipopolysaccharide-induced behavioral deficits and neuroinflammatory response: involvement of autophagy and NLRP3 inflammasome.
Jiang P, Guo Y, Dang R, Yang M, Liao D, Li H, Sun Z, Feng Q, Xu P
Journal of neuroinflammation 2017 Dec 6;14(1):239
Journal of neuroinflammation 2017 Dec 6;14(1):239
Rho/ROCK Pathway Regulates Migration and Invasion of Esophageal Squamous Cell Carcinoma by Regulating Caveolin-1.
Liu Z, Yu J, Wu R, Tang S, Cai X, Guo G, Chen S
Medical science monitor : international medical journal of experimental and clinical research 2017 Dec 30;23:6174-6185
Medical science monitor : international medical journal of experimental and clinical research 2017 Dec 30;23:6174-6185
CAPE-pNO(2) ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.
Wang X, Li D, Fan L, Xiao Q, Zuo H, Li Z
Oncotarget 2017 Dec 29;8(70):114506-114525
Oncotarget 2017 Dec 29;8(70):114506-114525
Synergistic inhibition of tumor growth by combination treatment with drugs against different subpopulations of glioblastoma cells.
Chang CH, Liu WT, Hung HC, Gean CY, Tsai HM, Su CL, Gean PW
BMC cancer 2017 Dec 29;17(1):905
BMC cancer 2017 Dec 29;17(1):905
Discovery of a Small-Molecule Bromodomain-Containing Protein 4 (BRD4) Inhibitor That Induces AMP-Activated Protein Kinase-Modulated Autophagy-Associated Cell Death in Breast Cancer.
Ouyang L, Zhang L, Liu J, Fu L, Yao D, Zhao Y, Zhang S, Wang G, He G, Liu B
Journal of medicinal chemistry 2017 Dec 28;60(24):9990-10012
Journal of medicinal chemistry 2017 Dec 28;60(24):9990-10012
Cadherin 6 is activated by Epstein-Barr virus LMP1 to mediate EMT and metastasis as an interplay node of multiple pathways in nasopharyngeal carcinoma.
Zuo LL, Zhang J, Liu LZ, Zhou Q, Du SJ, Xin SY, Ning ZP, Yang J, Yu HB, Yue WX, Wang J, Zhu FX, Li GY, Lu JH
Oncogenesis 2017 Dec 22;6(12):402
Oncogenesis 2017 Dec 22;6(12):402
Ultrasound reverses chemoresistance in breast cancer stem cell like cells by altering ABCG2 expression.
Guo L, Zheng P, Fan H, Wang H, Xu W, Zhou W
Bioscience reports 2017 Dec 22;37(6)
Bioscience reports 2017 Dec 22;37(6)
Indomethacin-based stimuli-responsive micelles combined with paclitaxel to overcome multidrug resistance.
Wang S, Tan X, Li S, Zhou Y, Geng P, Hua A, Deng A, Yu Z
Oncotarget 2017 Dec 19;8(67):111281-111294
Oncotarget 2017 Dec 19;8(67):111281-111294
De novo, deleterious sequence variants that alter the transcriptional activity of the homeoprotein PBX1 are associated with intellectual disability and pleiotropic developmental defects.
Slavotinek A, Risolino M, Losa M, Cho MT, Monaghan KG, Schneidman-Duhovny D, Parisotto S, Herkert JC, Stegmann APA, Miller K, Shur N, Chui J, Muller E, DeBrosse S, Szot JO, Chapman G, Pachter NS, Winlaw DS, Mendelsohn BA, Dalton J, Sarafoglou K, Karachunski PI, Lewis JM, Pedro H, Dunwoodie SL, Selleri L, Shieh J
Human molecular genetics 2017 Dec 15;26(24):4849-4860
Human molecular genetics 2017 Dec 15;26(24):4849-4860
Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells.
Wei X, Ye J, Shang Y, Chen H, Liu S, Liu L, Wang R
Oncotarget 2017 Dec 12;8(65):109301-109318
Oncotarget 2017 Dec 12;8(65):109301-109318
Adeno-associated virus 9-mediated Cdk5 inhibitory peptide reverses pathologic changes and behavioral deficits in the Alzheimer's disease mouse model.
He Y, Pan S, Xu M, He R, Huang W, Song P, Huang J, Zhang HT, Hu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Aug;31(8):3383-3392
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Aug;31(8):3383-3392
Effect of GAPT extract on expression of tau protein and its phosphorylation related enzymes in hippocampal neurons of APPV717I transgenic mice.
Ni JN, Shi J, Zhang XK, Yang YC, Liu XM, Wei MQ, Li T, Wang PW, Tian JZ, Wang YY
Chinese journal of integrative medicine 2017 Aug;23(8):605-610
Chinese journal of integrative medicine 2017 Aug;23(8):605-610
Ubiquitin C-terminal hydrolase-L3 promotes interferon antiviral activity by stabilizing type I-interferon receptor.
Zhao P, Guo T, Qian L, Wang X, Yuan Y, Cheng Q, Zuo Y, Liu J, Miao Y, Feng Q, Zhang L, Wu S, Zheng H
Antiviral research 2017 Aug;144:120-129
Antiviral research 2017 Aug;144:120-129
Palbociclib induces activation of AMPK and inhibits hepatocellular carcinoma in a CDK4/6-independent manner.
Hsieh FS, Chen YL, Hung MH, Chu PY, Tsai MH, Chen LJ, Hsiao YJ, Shih CT, Chang MJ, Chao TI, Shiau CW, Chen KF
Molecular oncology 2017 Aug;11(8):1035-1049
Molecular oncology 2017 Aug;11(8):1035-1049
NFATc3 mediates the sensitivity of gastric cancer cells to arsenic sulfide.
Zhang X, Kang T, Zhang L, Tong Y, Ding W, Chen S
Oncotarget 2017 Aug 8;8(32):52735-52745
Oncotarget 2017 Aug 8;8(32):52735-52745
Apoptosis pattern and alterations of expression of apoptosis-related factors of supporting cells in Kölliker's organ in vivo in early stage after birth in rats.
Liu J, Cai L, He Y, Yang J
European journal of histochemistry : EJH 2017 Aug 7;61(3):2706
European journal of histochemistry : EJH 2017 Aug 7;61(3):2706
Enteric dysbiosis-linked gut barrier disruption triggers early renal injury induced by chronic high salt feeding in mice.
Hu J, Luo H, Wang J, Tang W, Lu J, Wu S, Xiong Z, Yang G, Chen Z, Lan T, Zhou H, Nie J, Jiang Y, Chen P
Experimental & molecular medicine 2017 Aug 25;49(8):e370
Experimental & molecular medicine 2017 Aug 25;49(8):e370
Structure-based virtual screening and optimization of modulators targeting Hsp90-Cdc37 interaction.
Wang L, Li L, Zhou ZH, Jiang ZY, You QD, Xu XL
European journal of medicinal chemistry 2017 Aug 18;136:63-73
European journal of medicinal chemistry 2017 Aug 18;136:63-73
Exogenous H(2)S facilitating ubiquitin aggregates clearance via autophagy attenuates type 2 diabetes-induced cardiomyopathy.
Wu J, Tian Z, Sun Y, Lu C, Liu N, Gao Z, Zhang L, Dong S, Yang F, Zhong X, Xu C, Lu F, Zhang W
Cell death & disease 2017 Aug 10;8(8):e2992
Cell death & disease 2017 Aug 10;8(8):e2992
High expression of RBM8A predicts poor patient prognosis and promotes tumor progression in hepatocellular carcinoma.
Liang R, Lin Y, Ye JZ, Yan XX, Liu ZH, Li YQ, Luo XL, Ye HH
Oncology reports 2017 Apr;37(4):2167-2176
Oncology reports 2017 Apr;37(4):2167-2176
Upregulated unique long 16 binding protein 1 detected in preeclamptic placenta affects human extravillous trophoblast cell line (HTR-8/SVneo) invasion by modulating the function of uterine natural killer cells.
Liu J, Song G, Lin X, Pang X, Meng T
Experimental and therapeutic medicine 2017 Apr;13(4):1447-1455
Experimental and therapeutic medicine 2017 Apr;13(4):1447-1455
Endogenous Stem Cells Were Recruited by Defocused Low-Energy Shock Wave in Treating Diabetic Bladder Dysfunction.
Jin Y, Xu L, Zhao Y, Wang M, Jin X, Zhang H
Stem cell reviews and reports 2017 Apr;13(2):287-298
Stem cell reviews and reports 2017 Apr;13(2):287-298
Autoinhibition of Dishevelled protein regulated by its extreme C terminus plays a distinct role in Wnt/β-catenin and Wnt/planar cell polarity (PCP) signaling pathways.
Qi J, Lee HJ, Saquet A, Cheng XN, Shao M, Zheng JJ, Shi DL
The Journal of biological chemistry 2017 Apr 7;292(14):5898-5908
The Journal of biological chemistry 2017 Apr 7;292(14):5898-5908
A novel glutaminase inhibitor-968 inhibits the migration and proliferation of non-small cell lung cancer cells by targeting EGFR/ERK signaling pathway.
Han T, Guo M, Zhang T, Gan M, Xie C, Wang JB
Oncotarget 2017 Apr 25;8(17):28063-28073
Oncotarget 2017 Apr 25;8(17):28063-28073
Paper/PMMA Hybrid 3D Cell Culture Microfluidic Platform for the Study of Cellular Crosstalk.
Lei KF, Chang CH, Chen MJ
ACS applied materials & interfaces 2017 Apr 19;9(15):13092-13101
ACS applied materials & interfaces 2017 Apr 19;9(15):13092-13101
Tenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicity.
Zhao X, Sun K, Lan Z, Song W, Cheng L, Chi W, Chen J, Huo Y, Xu L, Liu X, Deng H, Siegenthaler JA, Chen L
Scientific reports 2017 Apr 11;7:46344
Scientific reports 2017 Apr 11;7:46344
Discovery of a small molecule targeting ULK1-modulated cell death of triple negative breast cancer in vitro and in vivo.
Zhang L, Fu L, Zhang S, Zhang J, Zhao Y, Zheng Y, He G, Yang S, Ouyang L, Liu B
Chemical science 2017 Apr 1;8(4):2687-2701
Chemical science 2017 Apr 1;8(4):2687-2701
The role of TGF-β-activated kinase 1 in db/db mice and high glucose-induced macrophage.
Xu X, Fan Z, Qi X, Shao Y, Wu Y
International immunopharmacology 2016 Sep;38:120-31
International immunopharmacology 2016 Sep;38:120-31
B7-H4 expression in human infiltrating ductal carcinoma‑associated macrophages.
Liu L, Li D, Chen S, Zhao R, Pang D, Li D, Fu Z
Molecular medicine reports 2016 Sep;14(3):2135-42
Molecular medicine reports 2016 Sep;14(3):2135-42
Interleukin-11 promotes epithelial-mesenchymal transition in anaplastic thyroid carcinoma cells through PI3K/Akt/GSK3β signaling pathway activation.
Zhong Z, Hu Z, Jiang Y, Sun R, Chen X, Chu H, Zeng M, Sun C
Oncotarget 2016 Sep 13;7(37):59652-59663
Oncotarget 2016 Sep 13;7(37):59652-59663
Functional characterization of hepatitis B virus core promoter mutants revealed transcriptional interference among co-terminal viral mRNAs.
Chen C, Jia H, Zhang F, Qin Y, Zong L, Yuan Q, Wang Y, Xia N, Li J, Wen Y, Tong S
The Journal of general virology 2016 Oct;97(10):2668-2676
The Journal of general virology 2016 Oct;97(10):2668-2676
Effect of Polygonatum odoratum extract on human breast cancer MDA-MB-231 cell proliferation and apoptosis.
Tai Y, Sun YM, Zou X, Pan Q, Lan YD, Huo Q, Zhu JW, Guo F, Zheng CQ, Wu CZ, Liu H
Experimental and therapeutic medicine 2016 Oct;12(4):2681-2687
Experimental and therapeutic medicine 2016 Oct;12(4):2681-2687
Afamin promotes glucose metabolism in papillary thyroid carcinoma.
Shen CT, Wei WJ, Qiu ZL, Song HJ, Luo QY
Molecular and cellular endocrinology 2016 Oct 15;434:108-15
Molecular and cellular endocrinology 2016 Oct 15;434:108-15
MicroRNA-181b suppresses TAG via target IRS2 and regulating multiple genes in the Hippo pathway.
Chen Z, Shi H, Sun S, Xu H, Cao D, Luo J
Experimental cell research 2016 Oct 15;348(1):66-74
Experimental cell research 2016 Oct 15;348(1):66-74
HSPB1 deficiency sensitizes melanoma cells to hyperthermia induced cell death.
Wang HX, Yang Y, Guo H, Hou DD, Zheng S, Hong YX, Cai YF, Huo W, Qi RQ, Zhang L, Chen HD, Gao XH
Oncotarget 2016 Oct 11;7(41):67449-67462
Oncotarget 2016 Oct 11;7(41):67449-67462
A comparison of incidences of bladder neck contracture of 80- versus 180-W GreenLight laser photoselective vaporization of benign prostatic hyperplasia.
Hu B, Song Z, Liu H, Qiao L, Zhao Y, Wang M, Song W, Zhang D, Jin X, Zhang H
Lasers in medical science 2016 Nov;31(8):1573-1581
Lasers in medical science 2016 Nov;31(8):1573-1581
Ubiquitin-dependent Turnover of Adenosine Deaminase Acting on RNA 1 (ADAR1) Is Required for Efficient Antiviral Activity of Type I Interferon.
Li L, Qian G, Zuo Y, Yuan Y, Cheng Q, Guo T, Liu J, Liu C, Zhang L, Zheng H
The Journal of biological chemistry 2016 Nov 25;291(48):24974-24985
The Journal of biological chemistry 2016 Nov 25;291(48):24974-24985
A novel transgenic mouse model of lysosomal storage disorder.
Ortiz-Miranda S, Ji R, Jurczyk A, Aryee KE, Mo S, Fletcher T, Shaffer SA, Greiner DL, Bortell R, Gregg RG, Cheng A, Hennings LJ, Rittenhouse AR
American journal of physiology. Gastrointestinal and liver physiology 2016 Nov 1;311(5):G903-G919
American journal of physiology. Gastrointestinal and liver physiology 2016 Nov 1;311(5):G903-G919
Foxo3b but not Foxo3a activates cyp19a1a in Epinephelus coioides.
Liu Q, Zhang Y, Shi B, Lu H, Zhang L, Zhang W
Journal of molecular endocrinology 2016 May;56(4):337-49
Journal of molecular endocrinology 2016 May;56(4):337-49
Valsartan Attenuates KIR2.1 by Downregulating the Th1 Immune Response in Rats Following Myocardial Infarction.
Li X, Hu H, Wang Y, Xue M, Li X, Cheng W, Xuan Y, Yin J, Yang N, Yan S
Journal of cardiovascular pharmacology 2016 Mar;67(3):252-9
Journal of cardiovascular pharmacology 2016 Mar;67(3):252-9
Human epithelial-type ovarian tumour marker beta-2-microglobulin is regulated by the TGF-β signaling pathway.
Sun W, Gui L, Zuo X, Zhang L, Zhou D, Duan X, Ren W, Xu G
Journal of translational medicine 2016 Mar 16;14:75
Journal of translational medicine 2016 Mar 16;14:75
AMPK activation protects cells from oxidative stress-induced senescence via autophagic flux restoration and intracellular NAD(+) elevation.
Han X, Tai H, Wang X, Wang Z, Zhou J, Wei X, Ding Y, Gong H, Mo C, Zhang J, Qin J, Ma Y, Huang N, Xiang R, Xiao H
Aging cell 2016 Jun;15(3):416-27
Aging cell 2016 Jun;15(3):416-27
Pancreatic cancer risk variant in LINC00673 creates a miR-1231 binding site and interferes with PTPN11 degradation.
Zheng J, Huang X, Tan W, Yu D, Du Z, Chang J, Wei L, Han Y, Wang C, Che X, Zhou Y, Miao X, Jiang G, Yu X, Yang X, Cao G, Zuo C, Li Z, Wang C, Cheung ST, Jia Y, Zheng X, Shen H, Wu C, Lin D
Nature genetics 2016 Jul;48(7):747-57
Nature genetics 2016 Jul;48(7):747-57
Deubiquitinase USP2a Sustains Interferons Antiviral Activity by Restricting Ubiquitination of Activated STAT1 in the Nucleus.
Ren Y, Zhao P, Liu J, Yuan Y, Cheng Q, Zuo Y, Qian L, Liu C, Guo T, Zhang L, Wang X, Qian G, Li L, Ge J, Dai J, Xiong S, Zheng H
PLoS pathogens 2016 Jul;12(7):e1005764
PLoS pathogens 2016 Jul;12(7):e1005764
Homologous recombination-dependent repair of telomeric DSBs in proliferating human cells.
Mao P, Liu J, Zhang Z, Zhang H, Liu H, Gao S, Rong YS, Zhao Y
Nature communications 2016 Jul 11;7:12154
Nature communications 2016 Jul 11;7:12154
Blockade of TGF-β-activated kinase 1 prevents advanced glycation end products-induced inflammatory response in macrophages.
Xu X, Qi X, Shao Y, Li Y, Fu X, Feng S, Wu Y
Cytokine 2016 Feb;78:62-8
Cytokine 2016 Feb;78:62-8
The PLC/PKC/Ras/MEK/Kv channel pathway is involved in uncarboxylated osteocalcin-regulated insulin secretion in rats.
Gao J, Bai T, Ren L, Ding Y, Zhong X, Wang H, Guo Y, Li J, Liu Y, Zhang Y
Peptides 2016 Dec;86:72-79
Peptides 2016 Dec;86:72-79
Nuclear PTEN interferes with binding of Ku70 at double-strand breaks through post-translational poly(ADP-ribosyl)ation.
Guan J, Zhao Q, Mao W
Biochimica et biophysica acta 2016 Dec;1863(12):3106-3115
Biochimica et biophysica acta 2016 Dec;1863(12):3106-3115
Berberine increases adipose triglyceride lipase in 3T3-L1 adipocytes through the AMPK pathway.
Jiang D, Wang D, Zhuang X, Wang Z, Ni Y, Chen S, Sun F
Lipids in health and disease 2016 Dec 9;15(1):214
Lipids in health and disease 2016 Dec 9;15(1):214
Novel Tetrahydropyrido[4,3-d]pyrimidines as Potent Inhibitors of Chaperone Heat Shock Protein 90.
Jiang F, Wang HJ, Jin YH, Zhang Q, Wang ZH, Jia JM, Liu F, Wang L, Bao QC, Li DD, You QD, Xu XL
Journal of medicinal chemistry 2016 Dec 8;59(23):10498-10519
Journal of medicinal chemistry 2016 Dec 8;59(23):10498-10519
Senescence: novel insight into DLX3 mutations leading to enhanced bone formation in Tricho-Dento-Osseous syndrome.
Zhao N, Han D, Liu H, Li Y, Wong SW, Cao Z, Xu J, Zhang X, Cai T, Wang Y, Feng H
Scientific reports 2016 Dec 7;6:38680
Scientific reports 2016 Dec 7;6:38680
H2O2 treatment or serum deprivation induces autophagy and apoptosis in naked mole-rat skin fibroblasts by inhibiting the PI3K/Akt signaling pathway.
Zhao S, Li L, Wang S, Yu C, Xiao B, Lin L, Cong W, Cheng J, Yang W, Sun W, Cui S
Oncotarget 2016 Dec 20;7(51):84839-84850
Oncotarget 2016 Dec 20;7(51):84839-84850
Chronic stress and excessive glucocorticoid exposure both lead to altered Neuregulin-1/ErbB signaling in rat myocardium.
Dang R, Guo Y, Zhang L, Chen L, Yang R, Jiang P
Steroids 2016 Aug;112:47-53
Steroids 2016 Aug;112:47-53
YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression.
Lyons SM, Achorn C, Kedersha NL, Anderson PJ, Ivanov P
Nucleic acids research 2016 Aug 19;44(14):6949-60
Nucleic acids research 2016 Aug 19;44(14):6949-60
Enhanced SLC34A2 in breast cancer stem cell-like cells induces chemotherapeutic resistance to doxorubicin via SLC34A2-Bmi1-ABCC5 signaling.
Ge G, Zhou C, Ren Y, Tang X, Wang K, Zhang W, Niu L, Zhou Y, Yan Y, He J
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Apr;37(4):5049-62
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Apr;37(4):5049-62
Protective effect of melatonin on myenteric neuron damage in experimental colitis in rats.
Shang B, Shi H, Wang X, Guo X, Wang N, Wang Y, Dong L
Fundamental & clinical pharmacology 2016 Apr;30(2):117-27
Fundamental & clinical pharmacology 2016 Apr;30(2):117-27
Arsenic sulfide, the main component of realgar, a traditional Chinese medicine, induces apoptosis of gastric cancer cells in vitro and in vivo.
Zhang L, Tian W, Kim S, Ding W, Tong Y, Chen S
Drug design, development and therapy 2015;9:79-92
Drug design, development and therapy 2015;9:79-92
Cardiac microvascular barrier function mediates the protection of Tongxinluo against myocardial ischemia/reperfusion injury.
Qi K, Li L, Li X, Zhao J, Wang Y, You S, Hu F, Zhang H, Cheng Y, Kang S, Cui H, Duan L, Jin C, Zheng Q, Yang Y
PloS one 2015;10(3):e0119846
PloS one 2015;10(3):e0119846
Elevated GAPDH expression is associated with the proliferation and invasion of lung and esophageal squamous cell carcinomas.
Hao L, Zhou X, Liu S, Sun M, Song Y, Du S, Sun B, Guo C, Gong L, Hu J, Guan H, Shao S
Proteomics 2015 Sep;15(17):3087-100
Proteomics 2015 Sep;15(17):3087-100
Gabarapl1 mediates androgen-regulated autophagy in prostate cancer.
Xie CW, Zhou Y, Liu SL, Fang ZY, Su B, Zhang W
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Nov;36(11):8727-33
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Nov;36(11):8727-33
MiR-101 sensitizes human nasopharyngeal carcinoma cells to radiation by targeting stathmin 1.
Sun Q, Liu T, Zhang T, Du S, Xie GX, Lin X, Chen L, Yuan Y
Molecular medicine reports 2015 May;11(5):3330-6
Molecular medicine reports 2015 May;11(5):3330-6
Formaldehyde exposure induces autophagy in testicular tissues of adult male rats.
Han SP, Zhou DX, Lin P, Qin Z, An L, Zheng LR, Lei L
Environmental toxicology 2015 Mar;30(3):323-31
Environmental toxicology 2015 Mar;30(3):323-31
Astrocyte elevated gene-1 promotes progression of cervical squamous cell carcinoma by inducing epithelial-mesenchymal transition via Wnt signaling.
Song E, Yu W, Xiong X, Kuang X, Ai Y, Xiong X
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2015 Mar;25(3):345-55
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2015 Mar;25(3):345-55
MiR-200c inhibits autophagy and enhances radiosensitivity in breast cancer cells by targeting UBQLN1.
Sun Q, Liu T, Yuan Y, Guo Z, Xie G, Du S, Lin X, Xu Z, Liu M, Wang W, Yuan Q, Chen L
International journal of cancer 2015 Mar 1;136(5):1003-12
International journal of cancer 2015 Mar 1;136(5):1003-12
G-protein coupled receptor 34 activates Erk and phosphatidylinositol 3-kinase/Akt pathways and functions as alternative pathway to mediate p185Bcr-Abl-induced transformation and leukemogenesis.
Zuo B, Li M, Liu Y, Li K, Ma S, Cui M, Qin Y, Zhu H, Pan X, Guo J, Dai Z, Yu W
Leukemia & lymphoma 2015 Jul;56(7):2170-81
Leukemia & lymphoma 2015 Jul;56(7):2170-81
8-p-Hdroxybenzoyl Tovarol Induces Paraptosis Like Cell Death and Protective Autophagy in Human Cervical Cancer HeLa Cells.
Zhang C, Jiang Y, Zhang J, Huang J, Wang J
International journal of molecular sciences 2015 Jul 2;16(7):14979-96
International journal of molecular sciences 2015 Jul 2;16(7):14979-96
Annexin A3 as a potential target for immunotherapy of liver cancer stem-like cells.
Pan QZ, Pan K, Wang QJ, Weng DS, Zhao JJ, Zheng HX, Zhang XF, Jiang SS, Lv L, Tang Y, Li YQ, He J, Liu Q, Chen CL, Zhang HX, Xia JC
Stem cells (Dayton, Ohio) 2015 Feb;33(2):354-66
Stem cells (Dayton, Ohio) 2015 Feb;33(2):354-66
Inhibition of JNK3 promotes apoptosis induced by BH3 mimetic S1 in chemoresistant human ovarian cancer cells.
Yang X, Xiang X, Xia M, Su J, Wu Y, Shen L, Xu Y, Sun L
Anatomical record (Hoboken, N.J. : 2007) 2015 Feb;298(2):386-95
Anatomical record (Hoboken, N.J. : 2007) 2015 Feb;298(2):386-95
Decreased expression of mucin-1 in endometriosis endometrium correlated with progesterone receptor B involved in infertility.
Shen F, Yan C, Liu M, Feng Y, Chen Y
Archives of gynecology and obstetrics 2015 Feb;291(2):439-45
Archives of gynecology and obstetrics 2015 Feb;291(2):439-45
Tolerance to endoplasmic reticulum stress mediates cisplatin resistance in human ovarian cancer cells by maintaining endoplasmic reticulum and mitochondrial homeostasis.
Xu Y, Wang C, Su J, Xie Q, Ma L, Zeng L, Yu Y, Liu S, Li S, Li Z, Sun L
Oncology reports 2015 Dec;34(6):3051-60
Oncology reports 2015 Dec;34(6):3051-60
IFIT5 positively regulates NF-κB signaling through synergizing the recruitment of IκB kinase (IKK) to TGF-β-activated kinase 1 (TAK1).
Zheng C, Zheng Z, Zhang Z, Meng J, Liu Y, Ke X, Hu Q, Wang H
Cellular signalling 2015 Dec;27(12):2343-54
Cellular signalling 2015 Dec;27(12):2343-54
Mitophagy in APPsw/PS1dE9 transgenic mice and APPsw stably expressing in HEK293 cells.
Wang X, Zhao XL, Xu LL, Wang CF, Wei LF, Liu Z, Yang H, Wang P, Xie ZH, Bi JZ
European review for medical and pharmacological sciences 2015 Dec;19(23):4595-602
European review for medical and pharmacological sciences 2015 Dec;19(23):4595-602
G1/S Cell Cycle Checkpoint Dysfunction in Lymphoblasts from Sporadic Parkinson's Disease Patients.
Esteras N, Alquézar C, Bartolomé F, de la Encarnación A, Bermejo-Pareja F, Molina JA, Martín-Requero Á
Molecular neurobiology 2015 Aug;52(1):386-98
Molecular neurobiology 2015 Aug;52(1):386-98
Lentivirus vector-mediated gene transduction of CNGRC peptide in rat adipose stem cells.
Meng D, Liu R, Pei L, Hou L, Ning Q, Yu Q, Feng L, Zhao X
Molecular medicine reports 2015 Apr;11(4):2555-61
Molecular medicine reports 2015 Apr;11(4):2555-61
Directional Plk1 inhibition-driven cell cycle interruption using amphiphilic thin-coated peptide-lanthanide upconversion nanomaterials as in vivo tumor suppressors.
Chan CF, Lan R, Tsang MK, Zhou D, Lear S, Chan WL, Cobb SL, Wong WK, Hao J, Wong WT, Wong KL
Journal of materials chemistry. B 2015 Apr 7;3(13):2624-2634
Journal of materials chemistry. B 2015 Apr 7;3(13):2624-2634
Neuropilin-1 promotes epithelial-to-mesenchymal transition by stimulating nuclear factor-kappa B and is associated with poor prognosis in human oral squamous cell carcinoma.
Chu W, Song X, Yang X, Ma L, Zhu J, He M, Wang Z, Wu Y
PloS one 2014;9(7):e101931
PloS one 2014;9(7):e101931
Altered expression of hypoxia-inducible factor-1α (HIF-1α) and its regulatory genes in gastric cancer tissues.
Wang J, Ni Z, Duan Z, Wang G, Li F
PloS one 2014;9(6):e99835
PloS one 2014;9(6):e99835
Proteomics approaches for identification of tumor relevant protein targets in pulmonary squamous cell carcinoma by 2D-DIGE-MS.
Lihong H, Linlin G, Yiping G, Yang S, Xiaoyu Q, Zhuzhu G, Xiaohan Y, Xin Z, Liyan X, Shujuan S
PloS one 2014;9(4):e95121
PloS one 2014;9(4):e95121
The association of HMGB1 gene with the prognosis of HCC.
Xiao J, Ding Y, Huang J, Li Q, Liu Y, Ni W, Zhang Y, Zhu Y, Chen L, Chen B
PloS one 2014;9(2):e89097
PloS one 2014;9(2):e89097
Tetramethylpyrazine ameliorates high glucose-induced endothelial dysfunction by increasing mitochondrial biogenesis.
Xu Q, Xia P, Li X, Wang W, Liu Z, Gao X
PloS one 2014;9(2):e88243
PloS one 2014;9(2):e88243
Prognostic value of myeloid differentiation primary response 88 and Toll-like receptor 4 in breast cancer patients.
Ma FJ, Liu ZB, Hu X, Ling H, Li S, Wu J, Shao ZM
PloS one 2014;9(10):e111639
PloS one 2014;9(10):e111639
Elevated MiR-222-3p promotes proliferation and invasion of endometrial carcinoma via targeting ERα.
Liu B, Che Q, Qiu H, Bao W, Chen X, Lu W, Li B, Wan X
PloS one 2014;9(1):e87563
PloS one 2014;9(1):e87563
Matrix metalloproteinase 3 promotes cellular anti-dengue virus response via interaction with transcription factor NFκB in cell nucleus.
Zuo X, Pan W, Feng T, Shi X, Dai J
PloS one 2014;9(1):e84748
PloS one 2014;9(1):e84748
Cytotoxicity induced by nanobacteria and nanohydroxyapatites in human choriocarcinoma cells.
Zhang M, Yang J, Shu J, Fu C, Liu S, Xu G, Zhang D
Nanoscale research letters 2014;9(1):616
Nanoscale research letters 2014;9(1):616
PNMA1 promotes cell growth in human pancreatic ductal adenocarcinoma.
Jiang SH, He P, Ma MZ, Wang Y, Li RK, Fang F, Fu Y, Tian GA, Qin WX, Zhang ZG
International journal of clinical and experimental pathology 2014;7(7):3827-35
International journal of clinical and experimental pathology 2014;7(7):3827-35
mTOR inhibitor AZD8055 inhibits proliferation and induces apoptosis in laryngeal carcinoma.
Zhao L, Teng B, Wen L, Feng Q, Wang H, Li N, Wang Y, Liang Z
International journal of clinical and experimental medicine 2014;7(2):337-47
International journal of clinical and experimental medicine 2014;7(2):337-47
Involvement of TLR4 in oxidized LDL/β2GPI/anti-β2GPI-induced transformation of macrophages to foam cells.
Zhang X, Xie Y, Zhou H, Xu Y, Liu J, Xie H, Yan J
Journal of atherosclerosis and thrombosis 2014;21(11):1140-51
Journal of atherosclerosis and thrombosis 2014;21(11):1140-51
Ganoderma lucidum polysaccharides target a Fas/caspase dependent pathway to induce apoptosis in human colon cancer cells.
Liang Z, Guo YT, Yi YJ, Wang RC, Hu QL, Xiong XY
Asian Pacific journal of cancer prevention : APJCP 2014;15(9):3981-6
Asian Pacific journal of cancer prevention : APJCP 2014;15(9):3981-6
Atorvastatin induces autophagy of mesenchymal stem cells under hypoxia and serum deprivation conditions by activating the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway.
Li N, Zhang Q, Qian H, Jin C, Yang Y, Gao R
Chinese medical journal 2014;127(6):1046-51
Chinese medical journal 2014;127(6):1046-51
Geniposide and its iridoid analogs exhibit antinociception by acting at the spinal GLP-1 receptors.
Gong N, Fan H, Ma AN, Xiao Q, Wang YX
Neuropharmacology 2014 Sep;84:31-45
Neuropharmacology 2014 Sep;84:31-45
Cryopreserved mouse fetal liver stromal cells treated with mitomycin C are able to support the growth of human embryonic stem cells.
Zhang W, Hu J, Ma Q, Hu S, Wang Y, Wen X, Ma Y, Xu H, Qian H, Xu W
Experimental and therapeutic medicine 2014 Sep;8(3):935-942
Experimental and therapeutic medicine 2014 Sep;8(3):935-942
USP33, a new player in lung cancer, mediates Slit-Robo signaling.
Wen P, Kong R, Liu J, Zhu L, Chen X, Li X, Nie Y, Wu K, Wu JY
Protein & cell 2014 Sep;5(9):704-13
Protein & cell 2014 Sep;5(9):704-13
Neuroprotective role of BNIP3 under oxidative stress through autophagy in neuroblastoma cells.
Awan MU, Hasan M, Iqbal J, Lei R, Lee WF, Hong M, Qing H, Deng Y
Molecular biology reports 2014 Sep;41(9):5729-34
Molecular biology reports 2014 Sep;41(9):5729-34
Dysregulation of vitamin D metabolism in the brain and myocardium of rats following prolonged exposure to dexamethasone.
Jiang P, Xue Y, Li HD, Liu YP, Cai HL, Tang MM, Zhang LH
Psychopharmacology 2014 Sep;231(17):3445-51
Psychopharmacology 2014 Sep;231(17):3445-51
In vitro and in vivo protection against enterovirus 71 by an antisense phosphorothioate oligonucleotide.
Liu J, Zhou Z, Li K, Han M, Yang J, Wang S
Archives of virology 2014 Sep;159(9):2339-47
Archives of virology 2014 Sep;159(9):2339-47
Lipoxin A4 methyl ester ameliorates cognitive deficits induced by chronic cerebral hypoperfusion through activating ERK/Nrf2 signaling pathway in rats.
Jin W, Jia Y, Huang L, Wang T, Wang H, Dong Y, Zhang H, Fan M, Lv P
Pharmacology, biochemistry, and behavior 2014 Sep;124:145-52
Pharmacology, biochemistry, and behavior 2014 Sep;124:145-52
Direct interaction of 14-3-3ζ with ezrin promotes cell migration by regulating the formation of membrane ruffle.
Chen M, Liu T, Xu L, Gao X, Liu X, Wang C, He Q, Zhang G, Liu L
Journal of molecular biology 2014 Sep 9;426(18):3118-3133
Journal of molecular biology 2014 Sep 9;426(18):3118-3133
Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology.
Orosco LA, Ross AP, Cates SL, Scott SE, Wu D, Sohn J, Pleasure D, Pleasure SJ, Adamopoulos IE, Zarbalis KS
Nature communications 2014 Sep 8;5:4692
Nature communications 2014 Sep 8;5:4692
Bone marrow mesenchymal stem cells repair spinal cord ischemia/reperfusion injury by promoting axonal growth and anti-autophagy.
Yin F, Meng C, Lu R, Li L, Zhang Y, Chen H, Qin Y, Guo L
Neural regeneration research 2014 Sep 15;9(18):1665-71
Neural regeneration research 2014 Sep 15;9(18):1665-71
A central role for TRPS1 in the control of cell cycle and cancer development.
Wu L, Wang Y, Liu Y, Yu S, Xie H, Shi X, Qin S, Ma F, Tan TZ, Thiery JP, Chen L
Oncotarget 2014 Sep 15;5(17):7677-90
Oncotarget 2014 Sep 15;5(17):7677-90
Cationic poly(amidoamine) dendrimers induced cyto-protective autophagy in hepatocellular carcinoma cells.
Li Y, Wang S, Wang Z, Qian X, Fan J, Zeng X, Sun Y, Song P, Feng M, Ju D
Nanotechnology 2014 Sep 12;25(36):365101
Nanotechnology 2014 Sep 12;25(36):365101
Ezrin is required for epithelial-mesenchymal transition induced by TGF-β1 in A549 cells.
Chen MJ, Gao XJ, Xu LN, Liu TF, Liu XH, Liu LX
International journal of oncology 2014 Oct;45(4):1515-22
International journal of oncology 2014 Oct;45(4):1515-22
Novel microRNA-like viral small regulatory RNAs arising during human hepatitis A virus infection.
Shi J, Sun J, Wang B, Wu M, Zhang J, Duan Z, Wang H, Hu N, Hu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2014 Oct;28(10):4381-93
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2014 Oct;28(10):4381-93
Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.
Xu D, Hu L, Su C, Xia X, Zhang P, Fu J, Wang W, Xu D, Du H, Hu Q, Song E, Song Y
Toxicology and applied pharmacology 2014 Oct 15;280(2):305-13
Toxicology and applied pharmacology 2014 Oct 15;280(2):305-13
Chronic stress causes neuroendocrine-immune disturbances without affecting renal vitamin D metabolism in rats.
Jiang P, Zhang L, Zhu W, Li H, Dang R, Tang M
Journal of endocrinological investigation 2014 Nov;37(11):1109-16
Journal of endocrinological investigation 2014 Nov;37(11):1109-16
MicroRNA-145 inhibits cell proliferation by directly targeting ADAM17 in hepatocellular carcinoma.
Liu Y, Wu C, Wang Y, Wen S, Wang J, Chen Z, He Q, Feng D
Oncology reports 2014 Nov;32(5):1923-30
Oncology reports 2014 Nov;32(5):1923-30
Toxic effects of levofloxacin on rat annulus fibrosus cells: an in-vitro study.
Bai ZL, Chen Q, Yang SD, Zhang F, Wang HY, Yang DL, Ding WY
Medical science monitor : international medical journal of experimental and clinical research 2014 Nov 8;20:2205-12
Medical science monitor : international medical journal of experimental and clinical research 2014 Nov 8;20:2205-12
Cholesterol-conjugated let-7a mimics: antitumor efficacy on hepatocellular carcinoma in vitro and in a preclinical orthotopic xenograft model of systemic therapy.
Liu YM, Xia Y, Dai W, Han HY, Dong YX, Cai J, Zeng X, Luo FY, Yang T, Li YZ, Chen J, Guan J
BMC cancer 2014 Nov 28;14:889
BMC cancer 2014 Nov 28;14:889
Phosphatidylinositol 3-kinase CB association with preoperative radiotherapy response in rectal adenocarcinoma.
Yu WD, Peng YF, Pan HD, Wang L, Li K, Gu J
World journal of gastroenterology 2014 Nov 21;20(43):16258-67
World journal of gastroenterology 2014 Nov 21;20(43):16258-67
Levels of human replication factor C4, a clamp loader, correlate with tumor progression and predict the prognosis for colorectal cancer.
Xiang J, Fang L, Luo Y, Yang Z, Liao Y, Cui J, Huang M, Yang Z, Huang Y, Fan X, Wang H, Wang L, Peng J, Wang J
Journal of translational medicine 2014 Nov 19;12:320
Journal of translational medicine 2014 Nov 19;12:320
Curcumin improves the integrity of blood-spinal cord barrier after compressive spinal cord injury in rats.
Yu DS, Cao Y, Mei XF, Wang YF, Fan ZK, Wang YS, Lv G
Journal of the neurological sciences 2014 Nov 15;346(1-2):51-9
Journal of the neurological sciences 2014 Nov 15;346(1-2):51-9
The sodium channel β1 subunit mediates outgrowth of neurite-like processes on breast cancer cells and promotes tumour growth and metastasis.
Nelson M, Millican-Slater R, Forrest LC, Brackenbury WJ
International journal of cancer 2014 Nov 15;135(10):2338-51
International journal of cancer 2014 Nov 15;135(10):2338-51
17β-Estradiol protects against apoptosis induced by levofloxacin in rat nucleus pulposus cells by upregulating integrin α2β1.
Yang SD, Ma L, Gu TX, Ding WY, Zhang F, Shen Y, Zhang YZ, Yang DL, Zhang D, Sun YP, Song YL
Apoptosis : an international journal on programmed cell death 2014 May;19(5):789-800
Apoptosis : an international journal on programmed cell death 2014 May;19(5):789-800
Nitro-oleic acid downregulates lipoprotein-associated phospholipase A2 expression via the p42/p44 MAPK and NFκB pathways.
Wang G, Ji Y, Li Z, Han X, Guo N, Song Q, Quan L, Wang T, Han W, Pang D, Ouyang H, Tang X
Scientific reports 2014 May 9;4:4905
Scientific reports 2014 May 9;4:4905
Microcystin-LR stabilizes c-myc protein by inhibiting protein phosphatase 2A in HEK293 cells.
Fan H, Cai Y, Xie P, Xiao W, Chen J, Ji W, Zhao S
Toxicology 2014 May 7;319:69-74
Toxicology 2014 May 7;319:69-74
Chemical characterization and antitumor activities of polysaccharide extracted from Ganoderma lucidum.
Liang Z, Yi Y, Guo Y, Wang R, Hu Q, Xiong X
International journal of molecular sciences 2014 May 22;15(5):9103-16
International journal of molecular sciences 2014 May 22;15(5):9103-16
A caspase-dependent pathway is involved in Wnt/β-catenin signaling promoted apoptosis in Bacillus Calmette-Guerin infected RAW264.7 macrophages.
Wu X, Deng G, Hao X, Li Y, Zeng J, Ma C, He Y, Liu X, Wang Y
International journal of molecular sciences 2014 Mar 21;15(3):5045-62
International journal of molecular sciences 2014 Mar 21;15(3):5045-62
HMG-CoA reductase is negatively associated with PCV2 infection and PCV2-induced apoptotic cell death.
Yang X, Ouyang H, Chen F, Pang D, Dong M, Yang S, Liu X, Peng Z, Wang F, Zhang X, Ren L
The Journal of general virology 2014 Jun;95(Pt 6):1330-1337
The Journal of general virology 2014 Jun;95(Pt 6):1330-1337
Downregulation of p16(ink4a) inhibits cell proliferation and induces G1 cell cycle arrest in cervical cancer cells.
Zhang CY, Bao W, Wang LH
International journal of molecular medicine 2014 Jun;33(6):1577-85
International journal of molecular medicine 2014 Jun;33(6):1577-85
Zebrafish Cacna1fa is required for cone photoreceptor function and synaptic ribbon formation.
Jia S, Muto A, Orisme W, Henson HE, Parupalli C, Ju B, Baier H, Taylor MR
Human molecular genetics 2014 Jun 1;23(11):2981-94
Human molecular genetics 2014 Jun 1;23(11):2981-94
TNF-α promotes early atherosclerosis by increasing transcytosis of LDL across endothelial cells: crosstalk between NF-κB and PPAR-γ.
Zhang Y, Yang X, Bian F, Wu P, Xing S, Xu G, Li W, Chi J, Ouyang C, Zheng T, Wu D, Zhang Y, Li Y, Jin S
Journal of molecular and cellular cardiology 2014 Jul;72:85-94
Journal of molecular and cellular cardiology 2014 Jul;72:85-94
Effects of natural mineral-rich water consumption on the expression of sirtuin 1 and angiogenic factors in the erectile tissue of rats with fructose-induced metabolic syndrome.
Pereira CD, Severo M, Rafael L, Martins MJ, Neves D
Asian journal of andrology 2014 Jul-Aug;16(4):631-8
Asian journal of andrology 2014 Jul-Aug;16(4):631-8
Ruthenium(II) polypyridyl complexes: cellular uptake, cell image and apoptosis of HeLa cancer cells induced by double targets.
Yu Q, Liu Y, Xu L, Zheng C, Le F, Qin X, Liu Y, Liu J
European journal of medicinal chemistry 2014 Jul 23;82:82-95
European journal of medicinal chemistry 2014 Jul 23;82:82-95
Lactobacillus casei reduces susceptibility to type 2 diabetes via microbiota-mediated body chloride ion influx.
Zhang Y, Guo X, Guo J, He Q, Li H, Song Y, Zhang H
Scientific reports 2014 Jul 18;4:5654
Scientific reports 2014 Jul 18;4:5654
Nanoscale chromatin profiling of gastric adenocarcinoma reveals cancer-associated cryptic promoters and somatically acquired regulatory elements.
Muratani M, Deng N, Ooi WF, Lin SJ, Xing M, Xu C, Qamra A, Tay ST, Malik S, Wu J, Lee MH, Zhang S, Tan LL, Chua H, Wong WK, Ong HS, Ooi LL, Chow PK, Chan WH, Soo KC, Goh LK, Rozen S, Teh BT, Yu Q, Ng HH, Tan P
Nature communications 2014 Jul 10;5:4361
Nature communications 2014 Jul 10;5:4361
Chondroprotective effects and multi-target mechanisms of Icariin in IL-1 beta-induced human SW 1353 chondrosarcoma cells and a rat osteoarthritis model.
Zeng L, Wang W, Rong XF, Zhong Y, Jia P, Zhou GQ, Li RH
International immunopharmacology 2014 Jan;18(1):175-81
International immunopharmacology 2014 Jan;18(1):175-81
Protection of ischemic post conditioning against transient focal ischemia-induced brain damage is associated with inhibition of neuroinflammation via modulation of TLR2 and TLR4 pathways.
Wang Y, Ge P, Yang L, Wu C, Zha H, Luo T, Zhu Y
Journal of neuroinflammation 2014 Jan 24;11:15
Journal of neuroinflammation 2014 Jan 24;11:15
Expression of SPRR3 is associated with tumor cell proliferation and invasion in glioblastoma multiforme.
Liu Q, Zhang C, Ma G, Zhang Q
Oncology letters 2014 Feb;7(2):427-432
Oncology letters 2014 Feb;7(2):427-432
MiR-451 increases radiosensitivity of nasopharyngeal carcinoma cells by targeting ras-related protein 14 (RAB14).
Zhang T, Sun Q, Liu T, Chen J, Du S, Ren C, Liao G, Yuan Y
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2014 Dec;35(12):12593-9
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2014 Dec;35(12):12593-9
Fluoride affects calcium homeostasis and osteogenic transcription factor expressions through L-type calcium channels in osteoblast cell line.
Duan XQ, Zhao ZT, Zhang XY, Wang Y, Wang H, Liu DW, Li GS, Jing L
Biological trace element research 2014 Dec;162(1-3):219-26
Biological trace element research 2014 Dec;162(1-3):219-26
MicroRNA-15b promotes neurogenesis and inhibits neural progenitor proliferation by directly repressing TET3 during early neocortical development.
Lv X, Jiang H, Liu Y, Lei X, Jiao J
EMBO reports 2014 Dec;15(12):1305-14
EMBO reports 2014 Dec;15(12):1305-14
Lentiviral vector-mediated RBM5 overexpression downregulates EGFR expression in human non-small cell lung cancer cells.
Su Z, Yin J, Zhao L, Li R, Liang H, Zhang J, Wang K
World journal of surgical oncology 2014 Dec 2;12:367
World journal of surgical oncology 2014 Dec 2;12:367
Blocking autophagy enhanced cytotoxicity induced by recombinant human arginase in triple-negative breast cancer cells.
Wang Z, Shi X, Li Y, Fan J, Zeng X, Xian Z, Wang Z, Sun Y, Wang S, Song P, Zhao S, Hu H, Ju D
Cell death & disease 2014 Dec 11;5(12):e1563
Cell death & disease 2014 Dec 11;5(12):e1563
The expression level of TRAF1 in human gastric mucosa is related to virulence genotypes of Helicobacter pylori.
Wang F, Bu G, Feng Q, Liu Z, Xu C, Shen S, Yuan Y
Scandinavian journal of gastroenterology 2014 Aug;49(8):925-32
Scandinavian journal of gastroenterology 2014 Aug;49(8):925-32
Reversal of multidrug resistance in vitro and in vivo by 5-N-formylardeemin, a new ardeemin derivative.
Zheng X, Li D, Zhao C, Wang Q, Song H, Qin Y, Liao L, Zhang L, Lin Y, Wang X
Apoptosis : an international journal on programmed cell death 2014 Aug;19(8):1293-300
Apoptosis : an international journal on programmed cell death 2014 Aug;19(8):1293-300
oxLDL/β2GPI/anti-β2GPI complex induced macrophage differentiation to foam cell involving TLR4/NF-kappa B signal transduction pathway.
Xu Y, Kong X, Zhou H, Zhang X, Liu J, Yan J, Xie H, Xie Y
Thrombosis research 2014 Aug;134(2):384-92
Thrombosis research 2014 Aug;134(2):384-92
Anthocyanin-rich fractions from red raspberries attenuate inflammation in both RAW264.7 macrophages and a mouse model of colitis.
Li L, Wang L, Wu Z, Yao L, Wu Y, Huang L, Liu K, Zhou X, Gou D
Scientific reports 2014 Aug 29;4:6234
Scientific reports 2014 Aug 29;4:6234
The crucial role of Atg5 in cortical neurogenesis during early brain development.
Lv X, Jiang H, Li B, Liang Q, Wang S, Zhao Q, Jiao J
Scientific reports 2014 Aug 11;4:6010
Scientific reports 2014 Aug 11;4:6010
si-DNMT1 restore tumor suppressor genes expression through the reversal of DNA hypermethylation in cholangiocarcinoma.
Xiang J, Luo F, Chen Y, Zhu F, Wang J
Clinics and research in hepatology and gastroenterology 2014 Apr;38(2):181-9
Clinics and research in hepatology and gastroenterology 2014 Apr;38(2):181-9
NLRP3 deficiency ameliorates neurovascular damage in experimental ischemic stroke.
Yang F, Wang Z, Wei X, Han H, Meng X, Zhang Y, Shi W, Li F, Xin T, Pang Q, Yi F
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2014 Apr;34(4):660-7
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2014 Apr;34(4):660-7
A synergic role of caspase-6 and caspase-3 in Tau truncation at D421 induced by H2O 2.
Zhao H, Zhao W, Lok K, Wang Z, Yin M
Cellular and molecular neurobiology 2014 Apr;34(3):369-78
Cellular and molecular neurobiology 2014 Apr;34(3):369-78
miR-200c inhibits metastasis of breast cancer cells by targeting HMGB1.
Chang BP, Wang DS, Xing JW, Yang SH, Chu Q, Yu SY
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2014 Apr;34(2):201-206
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2014 Apr;34(2):201-206
Epigallocatechin-3-gallate inhibits TF and TNF-α expression induced by the anti-β2GPI/β2GPI complex in human THP-1 cells.
Wang T, Zhou H, Xie H, Mu Y, Xu Y, Liu J, Zhang X
International journal of molecular medicine 2014 Apr;33(4):994-1002
International journal of molecular medicine 2014 Apr;33(4):994-1002
Association analysis of UGT1A genotype and haplotype with SN-38 glucuronidation in human livers.
Wang H, Bian T, Jin T, Chen Y, Lin A, Chen C
Pharmacogenomics 2014 Apr;15(6):785-98
Pharmacogenomics 2014 Apr;15(6):785-98
Activation of spinal glucagon-like peptide-1 receptors specifically suppresses pain hypersensitivity.
Gong N, Xiao Q, Zhu B, Zhang CY, Wang YC, Fan H, Ma AN, Wang YX
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Apr 9;34(15):5322-34
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Apr 9;34(15):5322-34
Ezh2 regulates adult hippocampal neurogenesis and memory.
Zhang J, Ji F, Liu Y, Lei X, Li H, Ji G, Yuan Z, Jiao J
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Apr 9;34(15):5184-99
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Apr 9;34(15):5184-99
Ubiquitin B in cervical cancer: critical for the maintenance of cancer stem-like cell characters.
Tian Y, Ding W, Wang Y, Ji T, Sun S, Mo Q, Chen P, Fang Y, Liu J, Wang B, Zhou J, Ma D, Wu P
PloS one 2013;8(12):e84457
PloS one 2013;8(12):e84457
Simvastatin alleviates hyperpermeability of glomerular endothelial cells in early-stage diabetic nephropathy by inhibition of RhoA/ROCK1.
Peng H, Luo P, Li Y, Wang C, Liu X, Ye Z, Li C, Lou T
PloS one 2013;8(11):e80009
PloS one 2013;8(11):e80009
NOD2 deficiency protects against cardiac remodeling after myocardial infarction in mice.
Li X, Li F, Chu Y, Wang X, Zhang H, Hu Y, Zhang Y, Wang Z, Wei X, Jian W, Zhang X, Yi F
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2013;32(6):1857-66
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2013;32(6):1857-66
Scutellarin attenuates hypertension-induced expression of brain Toll-like receptor 4/nuclear factor kappa B.
Chen X, Shi X, Zhang X, Lei H, Long S, Su H, Pei Z, Huang R
Mediators of inflammation 2013;2013:432623
Mediators of inflammation 2013;2013:432623
Anti-β2GPI/β2GPI stimulates activation of THP-1 cells through TLR4/MD-2/MyD88 and NF-κB signaling pathways.
Zhou H, Sheng L, Wang H, Xie H, Mu Y, Wang T, Yan J
Thrombosis research 2013;132(6):742-9
Thrombosis research 2013;132(6):742-9
Overexpression of 4EBP1, p70S6K, Akt1 or Akt2 differentially promotes Coxsackievirus B3-induced apoptosis in HeLa cells.
Li X, Li Z, Zhou W, Xing X, Huang L, Tian L, Chen J, Chen C, Ma X, Yang Z
Cell death & disease 2013 Sep 12;4(9):e803-9
Cell death & disease 2013 Sep 12;4(9):e803-9
L-3-n-butylphthalide protects against vascular dementia via activation of the Akt kinase pathway.
Huai Y, Dong Y, Xu J, Meng N, Song C, Li W, Lv P
Neural regeneration research 2013 Jul 5;8(19):1733-42
Neural regeneration research 2013 Jul 5;8(19):1733-42
Specific deletion of Cdc42 does not affect meiotic spindle organization/migration and homologous chromosome segregation but disrupts polarity establishment and cytokinesis in mouse oocytes.
Wang ZB, Jiang ZZ, Zhang QH, Hu MW, Huang L, Ou XH, Guo L, Ouyang YC, Hou Y, Brakebusch C, Schatten H, Sun QY
Molecular biology of the cell 2013 Dec;24(24):3832-41
Molecular biology of the cell 2013 Dec;24(24):3832-41
Nucleoside analog inhibits microRNA-214 through targeting heat-shock factor 1 in human epithelial ovarian cancer.
Chen YF, Dong Z, Xia Y, Tang J, Peng L, Wang S, Lai D
Cancer science 2013 Dec;104(12):1683-9
Cancer science 2013 Dec;104(12):1683-9
Astragaloside IV attenuates inflammatory cytokines by inhibiting TLR4/NF-кB signaling pathway in isoproterenol-induced myocardial hypertrophy.
Yang J, Wang HX, Zhang YJ, Yang YH, Lu ML, Zhang J, Li ST, Zhang SP, Li G
Journal of ethnopharmacology 2013 Dec 12;150(3):1062-70
Journal of ethnopharmacology 2013 Dec 12;150(3):1062-70
Identification and analysis of glycogen synthase kinase 3 beta1 interactome.
Gao X, Wang JY, Gao LM, Yin XF, Liu L
Cell biology international 2013 Aug;37(8):768-79
Cell biology international 2013 Aug;37(8):768-79
Concurrent blockade of NF-κB and Akt pathways potentiates cisplatin's antitumor activity in vivo.
Sun H, Zheng X, Wang Q, Yan J, Li D, Zhou Y, Lin Y, Zhang L, Wang X
Anti-cancer drugs 2012 Nov;23(10):1039-46
Anti-cancer drugs 2012 Nov;23(10):1039-46
Anti-inflammatory mechanism of taurine against ischemic stroke is related to down-regulation of PARP and NF-κB.
Sun M, Zhao Y, Gu Y, Xu C
Amino acids 2012 May;42(5):1735-47
Amino acids 2012 May;42(5):1735-47
Surgery upregulates high mobility group box-1 and disrupts the blood-brain barrier causing cognitive dysfunction in aged rats.
He HJ, Wang Y, Le Y, Duan KM, Yan XB, Liao Q, Liao Y, Tong JB, Terrando N, Ouyang W
CNS neuroscience & therapeutics 2012 Dec;18(12):994-1002
CNS neuroscience & therapeutics 2012 Dec;18(12):994-1002
Regulation of fibroblast growth factor-2 expression and cell cycle progression by an endogenous antisense RNA.
Baguma-Nibasheka M, Macfarlane LA, Murphy PR
Genes 2012 Aug 16;3(3):505-20
Genes 2012 Aug 16;3(3):505-20
Rosuvastatin treatment activates JAK-STAT pathway and increases efficacy of allogeneic mesenchymal stem cell transplantation in infarcted hearts.
Xu H, Yang YJ, Qian HY, Tang YD, Wang H, Zhang Q
Circulation journal : official journal of the Japanese Circulation Society 2011;75(6):1476-85
Circulation journal : official journal of the Japanese Circulation Society 2011;75(6):1476-85
Involvement of IRAKs and TRAFs in anti-β₂GPI/β₂GPI-induced tissue factor expression in THP-1 cells.
Xu G, Wen H, Zhou H, Guo D, Zhou F, Chen D, Xie H, Wang T, Wang H
Thrombosis and haemostasis 2011 Dec;106(6):1158-69
Thrombosis and haemostasis 2011 Dec;106(6):1158-69
Atorvastatin prevents mesenchymal stem cells from hypoxia and serum-free injury through activating AMP-activated protein kinase.
Dong Q, Yang Y, Song L, Qian H, Xu Z
International journal of cardiology 2011 Dec 15;153(3):311-6
International journal of cardiology 2011 Dec 15;153(3):311-6
Lentiviral-mediated siRNA targeted against osteopontin suppresses the growth and metastasis of gastric cancer cells.
Wang ZM, Cui YH, Li W, Chen SY, Liu TS
Oncology reports 2011 Apr;25(4):997-1003
Oncology reports 2011 Apr;25(4):997-1003
Perturbation of survivin expression affects chromosome alignment and spindle checkpoint in mouse oocyte meiotic maturation.
Sun SC, Wei L, Li M, Lin SL, Xu BZ, Liang XW, Kim NH, Schatten H, Lu SS, Sun QY
Cell cycle (Georgetown, Tex.) 2009 Oct 15;8(20):3365-72
Cell cycle (Georgetown, Tex.) 2009 Oct 15;8(20):3365-72
[Effects of paclitaxel and gefitinib on the proliferation and cell cycle of human lung adenocarcinoma cell SPC-A1.].
Jia G, Zhang W, Zhou J, Zhu Z
Zhongguo fei ai za zhi = Chinese journal of lung cancer 2008 Jun 20;11(3):339-44
Zhongguo fei ai za zhi = Chinese journal of lung cancer 2008 Jun 20;11(3):339-44
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The beta actin antibody from Proteintech is a mouse monoclonal antibody to a fusion protein of human beta actin. This antibody recognizes human,monkey,mouse,rat,hamster,zebra fish antigen. The beta actin antibody has been validated for the following applications: ELISA, IHC, IF, IP, WB analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using ACTB antibody 66009-1-lg at 1:200 dilution and Rhodamine-labeled goat anti-mouse IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-beta actin (IP:66009-1-Ig, 3ug; Detection:66009-1-Ig 1:10000) with HeLa cells lysate 3100ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 66009-1-Ig(Actin antibody) at dilution of 1:500 (under 40x lens)
- Sample type
- tissue
