66009-1-Ig

antibody from Proteintech Group

Targeting: ACTB

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunoprecipitation (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

66009-1-Ig

Provider

Proteintech Group

Proper citation

Proteintech Cat#66009-1-Ig, RRID:AB_2687938

Product name

beta actin antibody

Antibody type

Monoclonal

Description

KD/KO validated Beta Actin antibody (Cat. #66009-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat, hamster, zebrafish, monkey, dog and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.

Reactivity

Human, Mouse, Rat, Canine, Hamster, Simian, Zebrafish

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

2D4H5

Vial size

150ul

References

Submitted references

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Targeting the LHX1-LDB1 Complex Restores STING-dependent Senescence Surveillance and Inhibits Head and Neck Cancer Progression.

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Integrated single-cell transcriptomics and proteomics elucidate the molecular mechanisms and detoxification strategy of rifampicin-induced hepatotoxicity.

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Therapeutic effect and mechanism of different doses of aspirin on preterm delivery in pregnant mice.

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An Injectable Photothermal Responsive Liposome Hydrogel Co-Loaded with Bufalin, Apatinib, and IR820 for Inhibiting Postoperative Recurrence of Colon Cancer.

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Network Pharmacology Combined With Gut Microbiome and Serum Metabolomics Reveals the Therapeutic Mechanisms of Hydroxysafflor Yellow A in Diabetic Kidney Disease.

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IPO9 Promotes Ovarian Cancer Progression by Suppressing HMOX1-Dependent Ferroptosis.

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Gut-Derived Hippuric Acid Alleviates Hepatic Lipid Metabolism via UGDH/FOXK1/CD36 Axis in Obese Mice.

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GLUT5-Driven Gut-Liver Axis Injury Mediating Olanzapine-Induced NAFLD and Dapagliflozin Intervention.

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Ginsenoside Rg3 Mitigates LPS-Induced Injury in Human Bronchial Epithelial Cells by Restoring Autophagic Flux and Inhibiting the TLR4/NF-κB-Mediated Inflammatory Response.

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Decoding the role of RPL38 in lung adenocarcinoma: a multi-omics approach.

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Frontiers in immunology 2026;17:1778481

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Xiaoyao San alleviates emotional distress - induced TNBC growth through augmenting intratumoral CD8(+)T cell infiltration mediated by Rela/NF-kB-Cxcl9 axis.

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Frontiers in immunology 2026;17:1762492

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Yizong Tongluo formula attenuates idiopathic pulmonary fibrosis and inflammatory injury by inhibiting HIF-1α/LSH/SCD1-mediated ferroptosis.

Ma X, Wang X, Jiang D, Tuerxun Y, Tao S, Li F, Wei Y, Yang L, Xi L, Wang L
Frontiers in immunology 2026;17:1760615

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Metabolomics identifies chenodeoxycholic acid as a protective factor in diabetic foot ulcers.

Li Y, Guo R, Lv L, Jiang T, Zhang C, Chang J, Hu K, Peng H, Chen L, Chen R, Chen H, Ma Y
Frontiers in endocrinology 2026;17:1754743

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Meningeal lymphatic vessel dysfunction exacerbates brain injury in CVST mice via endoplasmic reticulum and oxidative stress pathways.

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Frontiers in immunology 2026;17:1745066

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A berberine-loaded hydrogel for the treatment of atopic dermatitis through antibacterial activity, inhibition of inflammation and modulation of oxidative stress.

Peng Z, Wei XY, Zeng X, Anwaier G, Zhou X, Shi BJ
Frontiers in immunology 2026;17:1740911

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Targeting the NSUN2-DHODH axis reverses ferroptosis resistance and oxaliplatin resistance in colorectal cancer.

Zhang J, Shen J, Zeng T, Gao C, Sheng B, Li J, Zeng W, Shen J, Shen C, Wang J, Wang J
Frontiers in pharmacology 2026;17:1739981

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RP-182 alleviated obstruction-induced renal fibrosis by reprogramming CD206(+) macrophages.

Cao H, Chen X, Jin R, Yang Y, Tao Y, Li P, Wu Y, Chen G, Zhao J, Wen J, Zhao Y, Wei L, Wei Z, Lu D, Chen Y, Liu D, Zhou H, Cheng J
Frontiers in pharmacology 2026;17:1739457

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Single-cell sequencing reveals reversible glial remodeling in the visual cortex during visual deprivation and recovery.

Gong X, Feng J, Xu Z, Xie Y, Han Y, Li J, Tang G, Liu Y, Dong X, Li S, Zhang J, Wang J, Liu R, Song J, Bi H
Frontiers in immunology 2026;17:1730619

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Components of Panax ginseng and Rhodiola rosea regulate mitophagy via the SIRT1/3-PGC-1α-NRF2 pathway to improve myocardial ischemia-reperfusion injury.

Yao M, Wang X, Wei H, Wang L, Zhang D, Liang Z, He R, He Y, Jiang L, Cui Y
Frontiers in pharmacology 2026;17:1716078

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Proteomic profiling of arteriovenous fistula tissue identifies dysregulated oxidoreductase proteins in diabetic end-stage renal disease.

Zhao B, Zhan S, Zhou X, Yu P, Wang Y
Frontiers in endocrinology 2026;17:1583065

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ROS-Responsive Double-Layer Microneedles Enable Sequential Antibacterial and Immunomodulatory Therapy for Infected Wound Healing.

Zhang H, Wang Z, Zhu Y, Huang T, Xiu Z, Huang H, Li H, Xie J, Huang H, Liu M, Sun L, Lan Y, Guo L
Theranostics 2026;16(4):2052-2079

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Mertk promotes early microglial-mediated synaptic engulfment in Alzheimer's disease.

Wu Y, Fan Y, Bao S, Song Y, Wang R, Wu J, Liu X, Jin J, Kong L, Hou B, Liang P, Chen T, Liu W, Peng B, He F, Zhou Y, Xu J, Chen Y, Han S, Yin J, He X
Theranostics 2026;16(3):1238-1261

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Reactive oxygen species/hypoxia dual-responsive polymers combined with melatonin inhibited PANoptosis of retinal ganglion cells for acute glaucoma treatment.

Meng S, Fang W, Wu Y, Xia Z, Chou T, Xia Y, Ding L, Zhou X, Xia X
Theranostics 2026;16(2):830-851

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Downregulation of PCYT2 by increased portal pressure safeguards liver regeneration after partial hepatectomy.

Pu G, Song Y, Li Q, Duan J, Wang G, Xiu W, Xu J, Zhao X, Dong W, Lan T, Ai R, Zhang J, Sun W, Kong D, Zhu Y, Zhang X, Liu Y, Wang C
Theranostics 2026;16(2):810-829

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A novel mouse cell line model reveals the tumor intrinsic and immune characteristics of EGFR-mutant lung cancer.

Yan Y, Shang J, Liu C, Chen Y, Bao Y, Zhao Y, Fan F, Sun Y, Zhou Y, Wu Y, Wang Y, Han H, Chen H, Pan Y
Theranostics 2026;16(2):1006-1022

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PTBP1-mediated inhibition of circular RNA SCMH1 biogenesis impairs brain recovery after ischemic stroke.

Bai Y, Han B, Zhang Y, Wen L, Liu C, Wang Y, Cui J, Zheng B, Cai N, Xu L, Shen L, Zhang Y, Yao H
Theranostics 2026;16(1):239-253

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Modified Dachengqi Decoction ameliorates sepsis-induced lung injury via the gut microbiota-bile acid axis.

Wu L, Peng W, Li Y, Yu L, Huang P, Ye Y, Feng Y, Chen B, Chen L
Frontiers in cellular and infection microbiology 2026;16:1661639

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IL20RB promotes proliferation and migration in clear cell renal cell carcinoma and is associated with immune infiltration.

Liu Y, Xie Y, Yan L, Luo Y, Liu D, Li Q, Xu W, Wang T
PeerJ 2026;14:e20898

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PLK1 overexpression as a dual-role biomarker and therapeutic vulnerability in pulmonary adenocarcinoma.

You L, Xu Y, Fu Y, Li J
PeerJ 2026;14:e20618

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The role of ASIC2 in glioma progression: implications for prognosis and therapeutic targeting.

Tian W, Wang Y, Wang Z, Peng F, Sun J, Qi H, Zhang Z, Wang P, Qiao S, Wang H, Dong J
PeerJ 2026;14:e20583

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Mechanistic insights into cadmium-induced hepatotoxicity mediated by dysregulation of microRNA expression.

Xu R, Liu Y, Gao R, Zhang Z, Feng Y, Yuan Y, Chen Z, Hu L
Frontiers in cell and developmental biology 2026;14:1787688

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Multi-scale systems toxicology defines a KLF5-centered adverse outcome pathway linking DEHP exposure to pancreatic cancer progression and signaling programs relevant to therapy tolerance.

Chen J, Pang H, Wang J, Guo J, Huang T, Zhou H
Frontiers in cell and developmental biology 2026;14:1769023

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Integrated bioinformatics and machine learning to explore the common mechanisms and potential biomarkers between periodontitis and preterm birth.

Mei F, Liu Y, Xu W, Liu R, Wang X, Li T, Chen Y, Wu T, Zhang W
Frontiers in cell and developmental biology 2026;14:1763374

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CaSR regulates SLC26A6 expression via the PKA-FOXO4 signaling axis to promote experimental calcium oxalate kidney stone formation in rats.

Gan L, Li W, Luo P, Zhang F, Zhong H, Xie M, Lu Y, Qian B, Zheng L
Frontiers in cell and developmental biology 2026;14:1746423

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A putative prognostic model for lung adenocarcinoma based on crotonylation-related genes by bioinformatics and experimental verification.

Wang W, Cui B, Li H, Zhen Z, Song X, Yuan X, Cui Q, Yuan Q, Liu Y
Frontiers in cell and developmental biology 2026;14:1639773

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Spinal cord injury-induced overflow incontinence reshapes the activin-follistatin-inhibin axis in mouse bladder and kidney.

Shen Y, Yang S, Zhou H, Zhu Y, Wang Z, Jiang W
Frontiers in molecular biosciences 2026;13:1752395

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Extracellular vesicles from Li-Qi-Yang-Yin formula attenuate LPS-stimulated inflammatory injury in human colonic epithelial cells in vitro by delivering bioactive metabolites and suppressing the oxidative stress-inflammation axis.

Deng X, Zhang W, Xu L, Ong SS, Zhang Y, Jian T, Xu T
Frontiers in medicine 2026;13:1751807

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Design, synthesis and anti-Alzheimer's disease activity evaluation of dual 17β-HSD10 and CDK5/p25 inhibitors based on the naphtho[2,3-b]furan-4,9-dione scaffold.

Dao S, Cui C, He W, Liu E, Zhang L, Tang H
European journal of medicinal chemistry 2026 Sep 5;313:118874

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Integrated LC-HRMS/MS-based metabolomics and in vitro and in vivo bioassays for comparative evaluation of two ethnomedicinal Paris species and their official counterparts.

Yu T, Sun Y, Qiu FN, Liu K, Liu CL, Pu QY, Li HJ
Journal of pharmaceutical and biomedical analysis 2026 Sep 15;278:117517

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A hybrid nanoadjuvant cascading activation of the cGAS-STING-IFN-Ⅰ pathway to enhance radio-immunotherapy.

Jiang Z, Zhang P, Cui G, Liu Y, Wang X, Zhou Z, Fei J, Wang K, Li Y, Zhang X, Shen H, Zeng S, Han Y, Shen J
Biomaterials 2026 Oct;333:124183

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Stromal cell-derived itaconate promotes endometriosis via macrophage NRF2 and lysosomal pH modulation.

Zhong Z, Wang S, Ren Q, Jiao X, Xu L, Dong X, Li N, Guan H, Chu R, Yuan M, Liu J, Du Y, Wei K, Yan L, Wang G
Redox biology 2026 May;92:104101

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Histone H3K9 lactylation activates the TXNIP/NLRP3 pathway to drive macrophage inflammation after spinal cord injury.

Shi C, Yuan F, Chen X, Xu S, Ding Y, Wen H, Duan C, Wu T, Lu H, Hu J, Xu J, Jiang L
Redox biology 2026 May;92:104078

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Design, Synthesis, Biological Evaluation, and Molecular Modeling Studies of Novel 2-Aminothiazole Derivatives as Potential FOXM1 Inhibitors for Triple-Negative Breast Cancer Therapy and Structure-Activity Relationship.

Abusharkh KAN, Çınar V, Onder A, Sıkık M, Mustafa Guzel, Hamurcu Z, Ozpolat B, Ay M, Comert Onder F
Drug development research 2026 May;87(3):e70296

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RNF26 regulating tumor immunogenicity of hepatocellular carcinoma by degrading GRP78 and instigating ER stress.

Luo J, Zhuo H, Zheng M, Fang Y, Wang X, Jin Y, Li Y, Du S, Wang J, Xue C, Jiang R, Li G
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 May;86:101375

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Hepatotoxicity induced by polylactic acid microplastics: The mediating role of gut microbiota and uric acid metabolism.

Deng Y, Li Z, Huang Y, Zhong Y, Qiu A, Chen X, Huang X, Yang X, Feng Y, Bai R, Fan B, Xian H, Li H, Chen D, Liang B, Huang Z
Journal of advanced research 2026 May;83:557-573

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Identification of Key Genes Associated With Epithelial Barrier Dysfunction by Comprehensive Analysis and Experimental Validation.

Liang S, Dong M, Zhu X, Wang S, Lin S, Li Y, Yi S, Wu D, Yang Z, Chen Y, Li J
Allergy 2026 May;81(5):1813-1832

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Plasma Proteomics Identifies Thousand-and-One-Amino Acid Kinase 3 as a Potential Biomarker of Rheumatoid Arthritis Activity and a Novel Therapeutic Target.

Xin P, Li W, A X, Shen J, Meng X, Bian Y, Han H, Xiang Z, Ran L, Sun S, Xie J, Yue T, Zhu Q, Zhang X, Xie L, Xiao L
Arthritis & rheumatology (Hoboken, N.J.) 2026 May;78(5):1045-1061

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PRAS40 activates the IRE1α-XBP-1-mediated unfolded protein response to exacerbate colorectal cancer by enhancing ST6Gal1-dependent α-2, 6 sialylation of GRP78.

Teng H, Guo Y, Chen X, Fan A, Zhang C, Zhang T, Luo Y, Huang L
Neoplasia (New York, N.Y.) 2026 May;75:101297

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The Cyclin C-CDK8/19 Mediator kinase module controls PRCC-TFE3 driven senescence in renal epithelium and tumorigenesis in TFE3-RCC.

Kuroda S, Funasaki S, Nishizawa H, Schmidt LS, Kurahashi R, Ito T, Arima Y, Tanaka M, Kitada A, James AM, Hasumi H, Jikuya R, Makiyama K, Kurotaki D, Minami T, Difilippantonio S, Linehan WM, Oike Y, Sawa T, Tanaka Y, Suda T, Yokokawa R, Nakamura T, Baba M, Kamba T
Neoplasia (New York, N.Y.) 2026 May;75:101296

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Statins targeting mevalonate-geranylgeranyl diphosphate pathway inhibit proliferation in NK/T lymphoma by promoting pyroptosis.

Wang Y, Mei M, Wang J, Wei L, Zhang M, Zhang M
Translational oncology 2026 May;67:102747

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PLOD2 Promotes Cutaneous Squamous Cell Carcinoma Progression in Association With STAT3-Related ERK and AKT Pathways.

Xian N, Wang Z, Wang B, Wang X, Zheng Y
Molecular carcinogenesis 2026 May;65(5):615-629

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Bioengineered extracellular vesicles escape lysosomal degradation and deliver Tet-PKM2 for macrophage immunometabolic reprogramming and periodontitis treatment.

Zhang WJ, Tian BM, Li F, Li X, Wu RX, Yin Y, Wang J, Deng DK, Chen YZ, Wang HY, Du YX, Wang X, Xiao Y, He XT, Chen FM
Bioactive materials 2026 May;59:607-628

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Knockdown of CCT2 inhibits the malignant progression of hepatocellular carcinoma cells by impairing STAT3 activation.

Li C, Yang L, Zhang Y, Zhao B, Qu H
Oncology reports 2026 May;55(5)

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Cinnamaldehyde inhibits the progression of gastric cancer by regulating glycolysis through PTP1B/PI3K/AKT/mTOR signaling pathway.

Qiao X, Xue D, Hu Z, Wang H, Mu L
Toxicology and applied pharmacology 2026 May;510:117775

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S-equol promotes ferroptosis in triple negative breast cancer by coordinating NCOA4-mediated ferritinophagy and PPARγ-mediated lipid metabolism.

Ni F, Huang Z, Cui Y, Huang P, Xue Z, Huang G, Zhao Y
Molecular and cellular biochemistry 2026 May;481(5):2119-2137

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Hypoxia-induced XBP1s-MYDGF axis suppresses ferroptosis through UBQLN1-mediated stabilization of LCN2 in gastric cancer.

Zhou Q, Qi H, Zou Y, Yue Z, Gan J, Xu H, Fan L, Wan H, Xin L
Oncogene 2026 May;45(19):1786-1799

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Thioredoxin-1 Inhibits Golgi Stress Induced by Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine.

Duan J, Sun X, Wei Y, Pan Y, Bai L, Yan F, Bai J
Antioxidants & redox signaling 2026 May;44(13-15):661-675

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Agomelatine Targets Aquaporin-4 Polarization to Rescue Glymphatic Dysfunction in Parkinson's Disease.

Wang S, Wu D, Chen G, Yuan J, Zheng L, Huang X, Liu X, Kang Z, Feng Y, Zhang J, Cai W, Lu Z, Wei L
Neuroscience bulletin 2026 May;42(5):1079-1094

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Exosomes From Cancer-Associated Fibroblasts Promote Colorectal Cancer Progression and Glutamine Metabolism Through METTL1-Mediated m7G Modification of SLC1A5 mRNA.

Zhang S, Chen Z, Ma C, Hu J, Lin S, Gao J, Chen S
Journal of gastroenterology and hepatology 2026 May;41(5):1541-1555

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Asperuloside-Mediated Activation of Nrf2 Inhibits the NF-κB Pathway and Suppresses Osteoarthritis Progression.

Zhu L, Shen H, Huang C, Jiang H, Yan Z, Pan X, Lu Z
Phytotherapy research : PTR 2026 May;40(5):3027-3046

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Epi-Berberine Alleviates Ulcerative Colitis, Protects the Intestinal Mucosal Barrier, and Inhibits Colonic Inflammation via Glutaminyl-Peptide Cyclotransferase in a Mouse Model of DSS-Induced Colitis.

Chen B, Liu K, Guo Y, Zhao J, Wang Y
Phytotherapy research : PTR 2026 May;40(5):3009-3026

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Periplogenin Suppresses Hepatocarcinogenesis by Inducing Cellular Senescence via the Activating FOXO1/P53 Signaling Pathway.

Wang P, Zhu J, Li W, He Z, Dai X, Shi Y, Xu Z, Wang P, Wang R, Chen J, Liang R, Huang J, Jiang Y, Chen G, Chen H, Xie X
Phytotherapy research : PTR 2026 May;40(5):2588-2603

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Polydatin Targets ACADVL to Combat Obesity by Promoting Adipocyte Browning and Activating Fatty Acid Oxidation.

He W, Gu Y, Zhang F, Xiang Y, Fang Y, Cai J, Li W, Wang Z, Qin G, Li K, Gu X, Lin X, Ma L, Hou Y, Xiao X, Luo T
Phytotherapy research : PTR 2026 May;40(5):2417-2436

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Puerarin Improves Glucose and Lipid Metabolism in Type 2 Diabetes by Regulating Gut Microbiota Homeostasis and Promoting Adipose Tissue Thermogenesis.

Cheng L, Gan M, Wang H, Song Y, Bai Y, Zhang D
Phytotherapy research : PTR 2026 May;40(5):2397-2416

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Angelica sinensis polysaccharides modulate iron metabolism and macrophage polarization to alleviate rheumatoid arthritis.

Zhan Y, Zhang H, Guo T, Qin H, Huang L, Wu N, Wang J, Mu X, Wang J, Li M, Wang K, Zhang Y
International journal of biological macromolecules 2026 May;364:152182

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Hyaluronic acid-coated Cu/Mn Prussian blue nanocubes amplify cuproptosis and cGAS-STING signaling for synergistic prostate cancer therapy.

Yao X, Ruan Y, Rao T, Lin F, Zhang W
International journal of biological macromolecules 2026 May;362:152036

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VSNL1 attenuates hypoxia‑induced myocardial apoptosis by regulating the CNP/NPRB pathway.

Yang X, Fang W, Chang R, Ma L, Chen X, Li Y
Molecular medicine reports 2026 May;33(5)

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Integrating network toxicology and experimental validation to elucidate the molecular mechanism basis of chondrotoxicity of Benzo[a]pyrene in osteoarthritis.

Pan J, Zhang Z, Ma Y, Gao Y, Wang Z, Ma J, Wang X
Ecotoxicology and environmental safety 2026 May;316:120177

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RIPK1-driven calcium overload and lysosomal-mitochondrial dysfunction induce testicular necroptosis following DEHP exposure.

Ran M, Yi R, Zhang H, Sun X, Qiu T, Li J, Wang N, Yao X, Zhang C, Deng H, Wang S, Yang G
Ecotoxicology and environmental safety 2026 May;316:120163

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Intrauterine exposure to glyphosate-based herbicide during pregnancy induces testicular impairment via activating ferroptosis in offspring.

Bai G, Wang R, Tong Y, Bai Y, Yuan H, Shi B, Teng T, He W
Ecotoxicology and environmental safety 2026 May;316:120123

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Embryonic exposure to bisphenol A glycidyl methacrylate induces craniofacial cartilage malformation via NLR signaling pathway in zebrafish.

Luo W, Zhang J, Wu S, Liao X, Xi W
Ecotoxicology and environmental safety 2026 May;316:120121

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Porcine reproductive and respiratory syndrome virus nsp2 protects viral RNA-dependent RNA polymerase from autophagic degradation.

Zhu T, Jiao X, Shi J, Wang B, Li C, Li Y
Veterinary microbiology 2026 May;316:110993

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L-2-aminoadipic acid inhibits porcine epidemic diarrhea virus replication by targeting and reducing cellular autophagy.

Ma X, Cui H, Song R, Huang Y, Li Y, Ma J, Chen H, Ma S, Wei Z
Veterinary microbiology 2026 May;316:110967

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Comparative RNA-seq analysis of Bovine parainfluenza virus type 3 and its V gene-deleted variant reveals that deletion of the V gene affects autophagy signaling.

Han Y, Wang A, Gao Y, Bai C, Ju M, Han B, Jing X, Wang C, Ren S
Veterinary microbiology 2026 May;316:110966

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C-type lectin domain family 11 member A protects osteogenic differentiation of mouse embryonic osteoblast precursor cells against lipotoxicity by inhibiting oxidative stress.

Zhang L, Zhang P, Tang M, Shi R
Cell stress & chaperones 2026 May;31(3):100175

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Exposure to magnesium oxide nanoparticles induces mitochondrial dysfunction and apoptosis in fish Megalobrama amblycephala by disrupting magnesium homeostasis.

Zhang L, Liu ZS, Xiong SS, Dong YZ, Guo YY, Zhang DD, Jiang GZ, Liu WB, Li XF
Aquatic toxicology (Amsterdam, Netherlands) 2026 May;294:107792

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Metabolomic changes following PMSG-induced estrus synchronization in Qianbei Ma goats.

Qiao FX, Ju YH, Wang XD, An PC, Ji Q, Li RY, Zeng TJ, Liu Q, Zhang DY, Feng ZH, Cao MS, Chen X
Animal reproduction science 2026 May;288:108145

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SIRT3 promotes oxaliplatin sensitivity in hepatocellular carcinoma by promoting ferroptosis through endoplasmic reticulum stress response.

Xu Y, Ma C, Xu X, Tu J, Chen X, Yang X, Sun D, Liu S, Wan Y, Qin L, Gu W, Qian H
Pathology, research and practice 2026 May;281:156400

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Lipid asymmetry disruption by XKR8 orchestrates neutrophil extracellular trap formation and inhibits fungal infection.

Liu W, Ping J, Deng L, Wang K, Xu J, Peng N, Yang M, Tang H, Liu Z, Wang W, Li T, Xie J, Han Y, Dong Z, Hu W, Liu Z, Wu N
Nature immunology 2026 May;27(5):949-960

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Endothelial cell-specific molecule 1 induced by interferon tau promotes angiogenesis in bovine endothelial cells.

Naito H, Kurata K, Yamazaki Y, Ukita H, Bai H, Kawahara M, Takasuka TE, Takahashi M
Theriogenology 2026 May;256:117855

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Antimicrobial peptide WK-13-3D inhibits Japanese encephalitis virus infection by interacting with viral particles, potentially targeting the envelope protein.

Chai F, Kassegn TA, Du J, Niu Q, Yang J, Guan G, Yin H, Wang X, Tian Z
Antiviral research 2026 May;249:106401

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miR-221 Mediates the Regulation of Phospholamban Expression and Cardiac Contractility by ZBTB20.

Ren QX, Liu YJ, Wang P, Song X, Zhao Q, Cao YN, Hui RT, Yang HT, Zhu Y, Wei CC, Ren AJ, Zhang WJ
Acta physiologica (Oxford, England) 2026 May;242(5):e70217

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Fei-Yan-Qing-Hua decoction inhibits influenza viral replication by enhancing NK cell maturation and activation through the upregulation of JAK/STAT/T-bet signalling axis.

Ma Y, Zhang W, Wu X, Xu G, Lei B, Zou Y, Liu S, Deng Y, Chen J, D'ursi P, Zhou C, Guo M, Yang X, Zheng Y
Pharmacological research 2026 May;227:108197

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Intelligent delivery of autophagy-targeting chimeric peptides by engineered exosomes for the degradation of α-synuclein.

Zeng Y, Lv Z, Liang J, Wu Y, Han L
Acta biomaterialia 2026 May;215:288-301

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Trimethyltin chloride triggers ferroptosis in myocardial injury: mitochondria-dependent protection by luteolin.

Wang P, Zhang X, Ding N, Liu A, Zhang S, Song Y, Yang L, He H, Chen M, Guo X, Zhang Y
Environment international 2026 May;211:110262

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Serine Supplementation Attenuates High-Selenium-Induced Insulin Resistance via Feedback Inhibition of PHGDH in Mice.

Wang J, Wang Q, Han F, Xiang X, Huang J, Fang C, Liu Y, Huang Z
Biological trace element research 2026 May;204(5):3309-3326

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Luteolin prevents hyperoxaluria-induced renal injury by inhibiting crystal deposition and renal inflammation.

Jin Z, Zhu S, Wang C, Wang T, Liu J, Wu Y
The international journal of biochemistry & cell biology 2026 May;194:106909

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Microvascular endothelial scavenger receptor class B type I protects against heart failure with preserved ejection fraction by inhibiting T-cell cardiotropism.

Wu Y, Yang X, Bai Y, Li C, Wang P, Xu Q, Li H, Rao X, Xu Y, Chen J, Cao H, Zhang Q, Zhao M, Zhan R, Fan X, Hou Y, Liu J, Lu HS, Wang T, Gao WD, Huang L, Xiao H, Zu L, Daugherty A, Xu M, Zheng L
EMBO molecular medicine 2026 May;18(5):1679-1706

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Betrixaban activates cGAS and ERVs to promote dual nucleic-sensing antiviral immunity.

Chen X, Zhao Y, Xie Y, Liu T, Wang H, Wang X, Guo X, You F
EMBO molecular medicine 2026 May;18(5):1563-1591

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Copy Number Amplification and c-Myc Transcriptional Activation-Mediated RNA-Binding Protein MEX3A Promotes EGFR-TKI Resistance in Non-Small-Cell Lung Cancer.

Xiling S, Lin D, Jiali D, Chen Z, Ruohan H, Chang Z, Renhua G, Jun L
Thoracic cancer 2026 May;17(9):e70284

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Echinacoside regulates the IRE1/XBP1 signaling pathway through HSP72 to reduce endoplasmic reticulum stress and improve diabetic kidney disease.

Geng R, Ma C, Wen L, Dai W, Liu J, Yang J, Hu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158062

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Curcumin augments mitophagy via Nrf2-PINK1-mediated, Parkin-dependent ubiquitination to suppress ferroptosis in post-cardiac arrest brain injury.

Li Z, Xu W, Ren S, Zheng Q, Xing J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158035

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Huzhang-Xiangbaji compounds enhance the repair of meniscal cartilage by inhibiting ferroptosis and inflammatory microenvironment.

Li J, Zhou J, Zhang G, Ding N, Kuang Z, Wang J, Liu N, Jia G, Jiang M, Wu S, Yang J, Ding X, Lei Z, Nie Y, Zhang Y, Li Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158008

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Yigan mingmu decoction treats diabetic retinopathy via Müller cell autophagy: A network pharmacology study.

Wang X, Hu ZY, Hu Q, Liu ZM, Chen XD
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158002

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Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta-on-a-Chip Model.

Liu H, Wang Y, Cai Y, Guo R, Liu S, Chen T, Sun T, Huo R, Liu T, Lv Q, Wang X
Advanced healthcare materials 2026 May;15(18):e04027

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Repurposing Hetrombopag for Multiple Myeloma by Targeting PNPO: A Celastrol-Inspired Approach.

Yu T, Wang C, Xie J, Wei Y, Cui H, Zhang H, Zhou F, Deng Z, Yang Y, Gu C
Basic & clinical pharmacology & toxicology 2026 May;138(5):e70227

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Salt-inducible kinase 1 is a key gene in suppressing EVD68-induced asthma by modulating antiviral immunity.

Liu J, Wang Y, Zou L, Han X, Lv M, Deng X, Liao J, Zang G, Xu L, Gu T, Lu N, Zhang G
Genes & diseases 2026 May;13(3):101845

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In Vivo CRISPR Screening Identifies the Glutamate Receptor GRIA2 as Promoting Peritoneal Metastasis of Gastric Cancer via Calcium-Dependent β-Catenin Activation.

Sun J, Yang X, Jiang W, Ji C, Wu Y, Sun H, Liu X, Yamamoto M, Tsukamoto T, Nomura S, Zhao J, Ruan Y, Li H, Wang X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(28):e21746

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Single-Cell Metabolic Imaging and Digital Scoring of Fat Tissue Remodeling by Label-Free Metabolic Microscopy.

Kim M, Berger C, Wolf A, Peteranderl A, Klingenspor M, Ntziachristos V, Li Y, Pleitez MA
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(28):e13042

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Dysregulation of the PATZ1/CTCF Balance Silences ZBTB20 to Drive Melanoma Progression.

Deng C, Cai S, Guo C, Khan S, Liu L, Tian Q, Ma Z, Zhang J, Zhao L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(26):e20917

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Decoding the Cardiac Immune Microenvironment and Fibroblast Crosstalk in Radiotherapy Combined with Immunotherapy-Induced Cardiac Fibrosis Based on Single-Cell Transcriptomic Analysis.

Luo Y, Yu Y, Zeng Z, Chen Y, Yi Y, Lu Z, Zeng F, Xu P, Luo D, Chen L, Liu A
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(25):e19216

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TEAD1 Enhances Exosome Secretion and Promotes Exosome-Mediated Tissue Regeneration.

Pu Y, Wan Y, Shi W, Li B, Zhang H, Wu J, Li L, Guo W, Ding C, Yang W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(25):e14104

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Proteomic profiling and molecular reclassification of high-grade serous ovarian cancer identifies prognostic subtypes and immunotherapy biomarkers.

Tu M, Tang S, Zhang Q, Guo T, Cen Y, Xu X, Wu S, Chen X, Lu W, Ding C, Xu J
EBioMedicine 2026 May;127:106248

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Reciprocal regulation between autism risk gene POGZ and circadian clock.

Wu T, He J, Xu CJ, Li CY, Zhang P, Wang Y, Zhu S, Zhang L, Zhu J, Zhang J, Li JD, Liu H
JCI insight 2026 May 8;11(9)

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AI-driven identification of a selective dual function inhibitor blocking HK2 activity and HK2-VDAC1 interaction displaying enhanced anticancer efficacy under hypoxia.

Shan W, Zhang SL, Assaraf YG, Tam KY
European journal of medicinal chemistry 2026 May 5;309:118752

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Tumor-Resident Streptococcus pneumoniae Promotes Malignant Progression and Pazopanib Resistance in Clear Cell Renal Cell Carcinoma.

Wang J, Nan Y, Liu Q, Ding T, Liu D, Duo L, Zhao J, Gao S, Zhang Y, Dai Z, Yan S, Zhang W, Li Z, Liu W, Han B, Zhao Y, Yu Y, Zhao E, Li X, You B
Cancer research 2026 May 4;86(9):2237-2252

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Multi-omics driven immune classification of colorectal cancer: Implications for immunotherapy efficacy prediction and enhancement with WNT signaling inhibition.

Hu C, Cai D, You W, Zhou Z, Liu J, Li CH, Lv MY, Gai BW, Chen C, Huang X, Wang RX, Wu XJ, Hu P, Gao F
Cancer letters 2026 May 28;646:218425

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Taohong siwu decoction alleviates hand-foot skin reaction by regulating RAGE-mediated keratinocyte apoptosis and autophagy.

Dong H, Liu Z, Yu F, Li J, Zheng Y, Shen Y, Wang A, Wu D, Wang X, Cui H, Peng Y
Journal of ethnopharmacology 2026 May 23;363:121401

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Saikosaponin D alleviates chronic prostatitis/chronic pelvic pain syndrome by regulating the NF-κB pathway via lncRNA5682.

Wang X, Zang Z, Zhou Y, Liu Z, Zhang H, Zhang K, Wang Z, Fu Q
Journal of ethnopharmacology 2026 May 23;363:121384

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Gynostemma pentaphyllum polysaccharides alleviate ulcerative colitis in mice via the Nrf2/ROS/NLRP3 axis and modulation of the gut microbiota.

Qiu M, Yi Q, Luo M, Duan S, Zhang Z, Wu X, Chen T, Ma C, Cui T, Zhang B, Zhang Y, Li J, Guo S, Gao Y, Zhang D
Journal of ethnopharmacology 2026 May 23;363:121373

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Epigenetically elevated RAD51AP1 regulates the RAD51-UAF1 complex contributing to temozolomide resistance in EGFRvIII glioblastoma.

Chang Y, Yang J, Li Z, Zhu X, Jiang T, Wang Q, Yu M, Han B, Liu X
Chinese medical journal 2026 May 20;139(10):1545-1556

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Porcine reproductive and respiratory syndrome virus N protein-mediated viral replication enhancement via interaction with host caspase-6.

Zhu D, Fu C, Dong Y, Zhang Q, Li H, Sun Y, Zhang G, Wang H
Journal of virology 2026 May 19;100(5):e0016326

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HAK-actin, a U-ExM-compatible probe to image the actin cytoskeleton.

Mercey O, Reymond L, Lemaître F, Mean I, Laporte MH, Olivetta M, Sadoul K, Dudin O, Hamel V, Guichard P
Cell reports methods 2026 May 18;6(5):101408

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LncRNA GAS5 regulates apoptosis in ovarian cancer cells by regulating O-GlcNAcylation of GOLGA8B.

Chen R, Wang J, Wang Z, Zhao G, Zhang J, Liu W, Wang Y
Gene 2026 May 15;991:150084

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Hepatic IFRD1 suppresses metabolic dysfunction-associated fatty liver disease via GLUD1/α-KG axis.

Geng M, Meng F, Li H, Sun L, Sun X, Ding Y, Shi R, Wang Z, Huang Y, Wang J, Liu Y, Wang J, Little PJ, Xu S, Liu L, Weng J, Luo S
Science bulletin 2026 May 15;71(9):2283-2299

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Eriodictyol mitigates polystyrene nanoplastic-induced ovarian toxicity via targeted inhibition of the TLR4/NF-κB/NLRP3 inflammatory axis.

Hu N, Gao Y, Fan R, Xue Y, Fang S, Wu S, Luo T, Hu L, Zhang D, Zheng L
Environmental pollution (Barking, Essex : 1987) 2026 May 15;397:128007

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Live and heat-treated Lactiplantibacillus plantarum induce distinct metabolic and immune responses in intestinal epithelial cells.

Matsumoto K, Takada Y, Imamura Y, Yoshida H, Sonomura K, Takahashi M, Moritoki N, Shindo T, Yamamoto J, Albarracin L, Ikeda-Ohtsubo W, Hori M, Villena J, Namai F, Tsujikawa Y, Hashimoto T, Nishiyama K, Kitazawa H
iScience 2026 May 15;29(5):115516

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Phenylephrine attenuates LPS-induced lung injury via Foxh1/GSK-3β/β-catenin-mediated alveolar epithelial cell differentiation in ARDS.

Zeng Z, Yin Y, Cong Z, Wei S, Wei X, Shen Z, Ge Q, Zhu X
International immunopharmacology 2026 May 15;177:116541

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Identification of Nitric Oxide-Donating Lenumlostat Derivatives with Dual Activities of Extracellular Matrix Dysregulation Inhibition and Pulmonary Vasodilation for the Treatment of Pulmonary Arterial Hypertension.

Hu Y, Wang Y, Tan W, Zhao C, Li M, Xiang S, Liang X, Gao R, Zeng B, Chen Z, Hu L, Li Q
Journal of medicinal chemistry 2026 May 14;69(9):11448-11470

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CircRNA-encoded RIPK1-98 protein drives lung adenocarcinoma progression.

Sun Q, Chi R, Zhang X, Chen T, Xu X, Ma L, Tian X, Miao Y, Yu Y, Kang R, Kroemer G, Shi Y, Tang D, Wang J
Developmental cell 2026 May 13;61(5):1092-1110.e12

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Tumor-immune-neural circuit disrupts energy homeostasis in cancer cachexia.

Shi X, Arreola AX, Zhou Z, Yang J, Liu M, Cai Y, Ren Y, Yuan H, Chen Q, Chen X, Yang X, Meng Y, Wang J, Luo W, Rudolph MC, Varshney R, Fung KM, Xu C, Chen WR, Bronze MS, Zheng L, Li YP, Houchen CW, Zhang Y, Li M
Cancer cell 2026 May 11;44(5):949-964.e6

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The HSP90-dependent bioorthogonal PROTAC prodrug system enables tumor-selective and enhanced protein degradation.

Yin F, Song T, Song Y, Wang K, Zhang H, Jiang M, Wang Z, Fan X, Zhang Y, Wang S, Teng Y, Lun H, Wang S, Xie A, Wang Z, Zhang Z
Journal of controlled release : official journal of the Controlled Release Society 2026 May 10;393:114828

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Salvia miltiorrhiza Bge. processed with porcine cardiac blood alleviates cerebral ischemia reperfusion injury through activating PPARγ/NF-κB pathway via suppressing arachidonic acid metabolism.

Zhou S, Jiang W, Sun Z, Zhang J, Zhang T, Ma B, Liu C, Zhang Y, Zhang L, Yan X
Journal of ethnopharmacology 2026 May 10;362:121385

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Sangbaipi Decoction mitigates influenza pneumonia in mice by inhibiting ZBP1-mediated PANoptosis.

Zhang C, Yu G, Liu M, Du R, Ma J, Gu X, Rong L, Lv X, Cui Q
Journal of ethnopharmacology 2026 May 10;362:121348

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Xuefu Zhuyu decoction attenuates thoracic aortic dissection by regulating VSMC phenotypic switching and oxidative stress via the JAK2/STAT3/HIF-1α pathway.

Cheng-Wen L, Rong G, Yi-Fan J, Shou-Jia W, Si-Yi L, Chun-Yan L, Fan L, Xiao-Qiang L, Wei-Xun D, Fan S
Journal of ethnopharmacology 2026 May 10;362:121324

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De novo design of protein binders that target DELE1 to inhibit the mitochondrial stress response.

Yang R, Zheng K, Metts M, Wang Y, Yin D, Li KP, Prazmowska AA, Kashatus DF, Kuhlman B, Yang J
bioRxiv : the preprint server for biology 2026 May 10;

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TGM2-mediated serotonylation in tumor endothelial cells promotes angiogenesis and tumor growth in colorectal cancer.

Ling T, Zhang W, Cai H, Kien TT, Yan T, Wang J, Chen J
Cancer letters 2026 May 1;645:218396

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PANX1-mediated NLRP3 inflammasome activation promotes an adaptive doxorubicin resistance through IL-1β signaling in breast cancer.

Yang C, Liu J, Kang X, Wang Z, Shang Q, Yue J, Li G, Dong X, Shang C, Wang T, Yang D, Wang X
Cancer letters 2026 May 1;645:218387

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Integrative single-cell and spatial transcriptomic reveals S100A16(+) tumor endothelial cells drive angiogenesis and immunosuppression in hepatocellular carcinoma.

Wang XX, Jin S, Chao X, Liu Y, Cheng YH, Ji H, Ai L, Gao Y, Sun G, Zhang J, Zhang HM
Cancer letters 2026 May 1;645:218335

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BAG3 modulates clathrin-mediated endocytosis and tau uptake in astrocytes.

Rodwell-Bullock J, Blau E, Ganguly A, Deaton C, Johnson GVW
American journal of physiology. Cell physiology 2026 May 1;330(5):C1286-C1295

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The structural characteristics, physicochemical properties, rheological behavior and anti-obesity effects of polysaccharides from Pueraria lobata: In-depth study focusing on the gut microbiota-hepatic FGF21 signaling.

Niu H, Deng Q, Hu B, Dong Y, Long Y, Zeng X, Zhang W, Duan Q, Huang Q, Zhang B, Dou Z, Zeng S
Food research international (Ottawa, Ont.) 2026 May 1;231(Pt 2):118717

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Isoliquiritigenin restores bone homeostasis in osteoporotic rats by enhancing BMSCs osteogenesis via ERK1/2-mTOR-HIF-1α-glycolytic axis and suppressing inflammation.

Chang H, Li Y, Wang Z, Fang Z, Chen H, Xu C, Jiao X, Gan Y
International immunopharmacology 2026 May 1;176:116440

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ZNRF2-mediated CD-M6PR degradation and lysosomal dysfunction aggravate cellular senescence and aging.

Zhao T, Xu W, Wang F, Chen H, Gong H, Yang Y, Huang N, Yang M, Zhang J, Gong C, Huang X, Li Y, Zhang C, Xiao H
GeroScience 2026 May 1;

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SLC38A4 promotes Kupffer cell phagocytosis and suppresses tumor liver metastasis.

Li J, Liu YD, Wang R, Lin XY, Zhu YQ, Lu WP, Tang YF, Guo XP, Ai YH, Xu TT, Lin S, Huang M, Wang J, Zhu XT, Yuan JH
Experimental & molecular medicine 2026 May 1;

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S-nitrosylation of HINT1 in macrophages aggravates foam cell formation and atherosclerosis.

Tang K, Zheng T, Zhu H, Xu F, Ma C, Qi Z, Cao S, Da Q, Yan K, Wu W, Han Y, Xie L, Zhang Y, Ji Y
Redox biology 2026 Mar;90:104063

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Small molecule HCY-NBD stabilizes GSTM2 via cys174 sulfenylation to attenuate high glucose induced endothelial cell senescence and calcification.

Zhang Y, Dong X, Yan X, Zhao C, Chi X, Zhao B, Miao J, Hong F, Lin Z
Redox biology 2026 Mar;90:104058

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Macrophage AMPK activated by oxidative stress drives profibrotic crosstalk with tubular cells to accelerate renal fibrosis after ischemic and reperfusion injury.

Tao Y, Zhang M, Chen L, Jia H, Yang Y, Wu Y, Li P, Wen Z, Zhang X, Chen X, Chen X, Li X, Zhou H
Redox biology 2026 Mar;90:104002

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DEAF1 confers resistance to adriamycin-induced apoptosis and pyroptosis in multiple myeloma.

Deng Z, Wei Y, Liu S, Chen L, Wang X, Liu Z, Liu L, Wang Y, Lv X, Sun S, Ni H, Gu C, Yang Y
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 Mar;85:101344

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Cadmium targeting MLKL-Drp1 axis to trigger mitochondrial oxidative stress contributes to necroinflammation in rat kidney.

Lian CY, Xia WH, Sun MC, Wan XM, Zhou XL, Wang L
Journal of advanced research 2026 Mar;81:1079-1093

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Targeting the ANXA2-CD63-exosomal PD-L1 axis in hepatocellular carcinoma: A novel mechanism of immune evasion and its implications for precision immunotherapy.

Zhang J, Gu Y, Zhao F, Chen Y, Xia Y, Gao D, Yuan Q, Bai X
Neoplasia (New York, N.Y.) 2026 Mar;73:101280

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KMO downregulation promotes hepatocellular carcinoma growth via 3‑HAA‑mediated mitochondrial mass and function imbalances

.

Liu M, Zhang X, Hu Y, Niu L, Guo L, Zhao G, Lu F, Jia F, Li L, Wu H, Zhu J
International journal of oncology 2026 Mar;68(3)

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Osteoblast-derived osteomodulin restrains osteoclastogenesis via ITGB8/RRM2-mediated reduction of mitochondrial respiration and mitochondrial ATP production.

Jiang X, Chen H, Hou W, Dai C, Zhang R, Chen E, Zhang J, Wu W, Xu J, Chen M, Liu L, Tan X, Ji X, Wu X, Wang K, Yu C, Yu X, Li W, Zhang W
Experimental & molecular medicine 2026 Mar;58(3):879-897

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Erythropoiesis-inosine metabolic axis failure underlying retinal neurodegeneration in glaucoma: novel diagnoses and therapies.

Chou Y, Liu W, Li Y, Chen C, Luo C, Shen S, Dai P, Feng L, Xiao W, Wang Y, Wang J, Wan L, Yang Z, Xie T, Zhang Y, Kellems RE, Song W, Xia X, Xia Y
Experimental & molecular medicine 2026 Mar;58(2):562-578

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Engineering multifunctional microspheres for sequential regulation of osteoimmune microenvironment and bone remodeling balance to promote regeneration of osteoporotic bone defects.

Luo Z, Ma J, Yang Y, Zhang H, Du Y, Dai J, Wang Y, Zhang W, Ma X, Lai Y
Journal of orthopaedic translation 2026 Mar;57:101054

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CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

.

Wang Y, Zhou H, Han X, Zhang D, Hou L, Li H, Fan T, Li S, Xue X
Oncology reports 2026 Mar;55(3)

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γδTreg/γδTh17 Cell Imbalance Drives Xanthine-Mediated Metabolic Dysfunction in Restraint Stress-Induced Anxiety-Like Behavior.

Xue X, Tang C, Yan N, Lai X, Li Q, Li E
Cell biology international 2026 Mar;50(3):e70149

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Anti-skin aging effects of black ginseng extracts through regulating inflammatory factors and the CLOCK-ERK pathway in mice.

Huang Y, Wang B, Jin Y, Qiu M, Liu J, Hao L, Zhang C, Ma H
Journal of ginseng research 2026 Mar;50(2):100926

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Inhibiting mPGES-2 impedes renal cyst growth in mice with polycystic kidney disease.

Zhong DD, Hu C, Zhao LL, Shen Y, Zhang RM, Liu Y, Liu BH, Su W, Yang BX, Xiong H, Guo D, Sun D, Zou YY, Sun Y
Acta pharmacologica Sinica 2026 Mar;47(3):689-700

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YEATS2 promotes DNA repair and induces anoikis resistance by enhancing chromatin accessibility to drive prostate cancer metastasis.

Li H, Song Y, Cong Y, Wang C, Chen K, Liu C, Zhou M, Ju Y, Chen J, Chen L, Xing Y
Oncogene 2026 Mar;45(11):971-988

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Role of ITIH4 in Modulating YAP/TAZ-Mediated Apoptosis of Type II Alveolar Epithelium during Acute Respiratory Distress Syndrome.

Shih YS, Chen XY, Lin YW, Liao ZA, Liu YH, Laiman V, Peng SW, Ito K, Chuang HC
Pharmaceutical research 2026 Mar;43(3):619-633

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Sulforaphane Attenuates Methamphetamine-Induced Neurotoxicity via Activation of the PI3K/AKT Pathway.

Li S, Zhang J, Li X, Zhang G, Ren L, Yang C, Niu S, Cui W, Wang Y, Yan J
Journal of biochemical and molecular toxicology 2026 Mar;40(3):e70769

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Single-Molecule All-In-One (SMALL) Dendritic Dots for Precise Cancer Theranostics.

Sun Y, Zheng Y, Wang Z, Gao K, Zhu Y, Zhao Z, Piao Y, Dong C, Shen Y, Zhou Z
Advanced materials (Deerfield Beach, Fla.) 2026 Mar;38(18):e08639

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Anxiety and abnormal hippocampal neurogenesis in adult rat offspring after high-speed train indoor pressure exposure during early pregnancy.

Zhang X, Deng Y, Zhang W, Wang T, Qian B, Dai L
International journal of environmental health research 2026 Mar;36(3):541-553

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α-Conotoxin LvID, an antagonist of α7 nicotinic acetylcholine receptor, mitigates Alzheimer-associated phenotypes by inhibiting Aβ deposition and reactive astrogliosis.

Yue S, Xing H, Du X, Wang Y, Qin R, He J, Yu J, Zhangsun D, Craik DJ, McIntosh JM, Wu Y, Zhu X, Luo S
International journal of biological macromolecules 2026 Mar;349:150933

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E3 ubiquitin ligase DTX3L promotes breast cancer progression by enhancing PKCα ubiquitination and inhibiting the p38 MAPK signaling pathway.

Zhang X, Song Y, Shi C, Yu D, Li S
International journal of biological macromolecules 2026 Mar;349:150861

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Pathological mechanism of ferroptosis in a rat model of α‑naphthyl isothiocyanate‑induced chronic cholestasis

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Guo Z, Wang J, Wang Y, Liu X, Xia Y, Liu P, Qi L, Liu J, Wang X
Molecular medicine reports 2026 Mar;33(3)

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Rapamycin Reduces Amyloid-β Plaques and Improves Behavioral Performance in a Sex-Dependent Manner in Mouse Models of Amyloidosis.

Guo S, Fu W, Wang Y, Liu Q, Li J, Guo K, Zhang H
CNS neuroscience & therapeutics 2026 Mar;32(3):e70807

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Trehalose Alleviates the Advancement of Temporomandibular Joint Osteoarthritis via Regulating the AMPK/ULK1 Autophagy Pathway.

Xu J, Liu Y, Zhu S, Yu W, Kang H, Bao G
Oral diseases 2026 Mar;32(3):809-821

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ZNF16 inhibits PEDV replication through autophagy-mediated degradation of S1 protein.

Zheng D, Yang X, Qin W, Gao A, Liu Y, Sun H, Tong W, Yu H, Zheng H, Tong G, Shan T, Zhang Y, Kong N, Zheng L
Veterinary microbiology 2026 Mar;314:110912

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Alix-mediated selective packaging of β-catenin into extracellular vesicles enhances their proangiogenic function.

Li R, Pan K, Zhang Q, Guo Y, Jung N, Han Z, Han ZC, Zhang J, Li Z
The Journal of biological chemistry 2026 Mar;302(3):111254

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TSG101 Promotes SIAH1 Auto-Ubiquitination to Drive Migration and Invasion in Hepatocellular Carcinoma Cells.

Qiu J, Gu X, Wu K, Wu J, Xu C, Shan W, Shi H
Journal of cellular and molecular medicine 2026 Mar;30(6):e71109

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Insulin-like growth factor 2 alleviates metabolic inflammation and associated cognitive impairment in diet-induced obesity mice.

Liu X, Chen L, Chen Y, Huang Y, Xiao X, Zhong X
Diabetes, obesity & metabolism 2026 Mar;28(3):1800-1816

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Decreased Glucose Metabolism and Declined Chaperones Are Unique Features Required for the Survival of Senescent Fibroblasts and Pyruvate Dehydrogenase Is a Potent Senolytic Target.

Zhang M, Hu Z, Piao S, Song Y, Jia Y, Liu J, Zhao N, Liu A, Fu S, Sun W, Xu H, Yang Y, Gygi SP, Zhou C
Aging cell 2026 Mar;25(3):e70434

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Engineered Bacillus subtilis WB600/ZD reduces post-weaning diarrhea in piglets by modulating gut microbiota and aryl hydrocarbon receptor (AHR) signaling.

Li W, Wang X, Zhang Y, Yang H, Wang X, Meng W, Hu T, Zhang W, Zhu Y, Wang J, Yang G
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2026 Mar;24:46-60

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A novel black soldier fly protein hydrolysate improves the muscle growth of rainbow trout (Oncorhynchus mykiss) via the PI3K/AKT/mTOR pathway.

Chen Y, Li X, Chen A, Liao Z, Gu X, Chen X, Ye T, Zhang W, He X, Li W, Zhu B, Hu P, Zhu X, Du Z, Zhao W, Niu J
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2026 Mar;24:278-290

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Arenarine D Promotes Pancreatic β Cell Proliferation Via DYRK1A Inhibition for T1DM Therapy.

Wang C, Huang Q, Gao S, Zhu Q, Lin T
Chemistry & biodiversity 2026 Mar;23(3):e71132

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Persistent histone H3K27 acetylation contributes to excessive scar formation after spinal cord injury through the regulation of microglial cholesterol accumulation.

Qiao Q, Gong Q, Li N, Sun H, Ru X, Mu N, Chen B, Li W, Chen T, Feng H, Chen Y, Cheng H
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Mar;23(2):e00868

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Oridonin induces ferroptosis by inhibiting ubiquitin-mediated degradation of HMOX1 in hepatocellular carcinoma.

Min L, Wang H, Qi H
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 Mar;209:115905

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Mdivi-1 alleviates aseptic craniofacial osteolysis via inhibition of PINK1/Parkin-dependent mitophagy.

Sun X, Liu B, Li Z, Zhou S, Wang Z, Yu J, Nie Q, Zhu L
Bone 2026 Mar;204:117738

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Ubiquitin-specific peptidase 40 promotes cellular proliferation and inhibits apoptosis through deubiquitination-mediated stabilization of c-MYC in acute myeloid leukemia.

Fu W, Wu Q, Yao Y, Sun Y, Wang H, Jie J, Zheng X, Wang L, Hu X, Tong X, Xu Q
Biochimica et biophysica acta. Molecular basis of disease 2026 Mar;1872(3):168138

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Cell metabolomics to reveal the mechanism of saponins and alkaloids on prostate inflammation via COX and LOX pathways.

Liu L, Xue L, Hou G, Zhang J, Tian L, Wang X, Dai R
Prostaglandins & other lipid mediators 2026 Mar;183:107066

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CXCL2-PI3K/AKT/NF-κB Signalling Axis Drives Neutrophil Activation and Inflammation in Systemic Lupus Erythematosus: Implications for Targeted Therapeutic Strategies.

Xu C, Zhou Y, Huang X, Pu YJ, Cao W, Yuan L, Wu Y, Deng D, Yang B
Immunology 2026 Mar;177(3):512-525

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The role of IRF1 in positive feedback of type I IFN transcription to combat Siniperca chuatsi rhabdovirus (SCRV) infection in teleost fish.

Li L, Wang KL, Li N, Peng XY, Liu LH, Chen SN, Nie P
Developmental and comparative immunology 2026 Mar;176:105567

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Crebanine protects against ovariectomy-induced bone loss by targeting Sirt1 to interfere with NF-κB acetylation and ROS activity.

Zhang H, Zhao X, Wang Z, Miao J, Hu X, Cui P, Jin C, Zhao X, Liang H, Ye H, Xu Y, Chen X, Wang W, Lu S
Journal of pharmaceutical analysis 2026 Mar;16(3):101426

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Identification and Validation of cGAS-STING Pathway-Associated Predictive and Therapeutic Models for Esophageal Squamous Cell Cancer Patients via Artificial Intelligence and Multi-Omics.

Zhou C, Liu X, Wang Z, Yang T
Cancer medicine 2026 Mar;15(3):e71645

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CAPZA1 Suppressed the Progression of Esophageal Squamous Cell Carcinoma by Binding to hnRNP K and PTPB1 to Influence Its mRNA Stability.

Kang N, Ou Y, Guo S, Chen J, Li D, Zhan Q
Cancer medicine 2026 Mar;15(3):e71587

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Traditional Chinese Herbal Formula XuMingZhuSan Alleviates Neuronal Ferroptosis in Rats After Stroke by Activating the NRF2/GPX4/SLC7A11 Pathway.

Liu X, Wang C, Han L, Xiao Y, Yu H, Hu Z, Fei X, Peng M, Zhou J, Zhong Z
Food science & nutrition 2026 Mar;14(3):e71495

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The anti-aging drug Senolytics alleviates vascular endothelial cell senescence by antagonizing the JPX-BRD4-p65 complex.

Mao K, Zhu W, Sun H, Zheng H, Fu Z
Cellular signalling 2026 Mar;139:112342

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Macrophage κ-opioid receptor inhibits hypoxic pulmonary hypertension progression and right heart dysfunction via an SCD1-dependent anti-inflammatory response.

Wang Q, Liu J, Li R, Kong S, Wang Y, Huang G, Zhang S, Feng N, Gu X, Liu Y, Jia M, Fu F, Li J, Li J, Pei J
Genes & diseases 2026 Mar;13(2):101604

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PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis.

Su T, Li G, Guan Y, Tian Q, Qi Y, Zhang Y, Wei W, Duan X, Rui J, Zhu H, Lin Z, Xie C, Xu Z, Wu Y, Peng X, Wang Z, Chen K, Xin X, Zhang B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(13):e21525

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Endoplasmic reticulum stress-induced CHOP activation mediates NLRP3 inflammasome-dependent pyroptosis in BDE-47-induced cognitive dysfunction.

Yuan Q, Zhang R, Hu J, Lin S, Zhu Y, Geng J, Du G, Yang X, Zhao Y, Wang D, Wang B, Fan H
Neurotoxicology 2026 Mar;113:103409

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Multi-omics mapping identifies CYBA-mediated mitochondrial dysfunction driving macrophage polarization and ferroptosis via Nrf2 pathway in atherosclerosis.

Dong C, Shen R, Pan C, Zhang J, Yu K, Zeng Q
APL bioengineering 2026 Mar;10(1):016107

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Transforming Growth Factor-β Drives Epithelial Mesenchymal Transition and Reduces Synthesis of Unelaborated O-GalNAc Glycans in Breast Cancer Cells.

Cull J, Pink RC, Samuel P, Brooks SA
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2026 Mar-Apr;74(2):193-214

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TGEV activates RIG-I/IFN-β/STAT1 axis to promote NLRC5-mediated SLA-I upregulation.

Wang W, Ma M, Bai H, Sun Y, Liu B, Gao A, Pan Q, Zheng D, Li M, Jiang W, Ma S, Wei Z, Zhang H, Zheng L
Veterinary research 2026 Mar 9;57(1)

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Identification and Validation of MTFP1 as a Mitochondrial Target Restoring Dynamics and ECM Remodeling in Acute Myocardial Infarction.

Hu X, Bao H, Huang Y, Cao Z, Yang W, Huang C, Chen X, Chen Y, Chen B, Xia G, Yang X, Huang R, Chen Z
Current issues in molecular biology 2026 Mar 9;48(3)

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Chemotherapy triggers immune evasion by fostering LEPR(+) Kupffer cell differentiation in liver metastases.

Wang X, Pan Q, Li Y, Li N, Guo J, Gu Y, Zhang G, Lian Y, Liu H, Cao L, Zhang W, Lin N, Xu B, Jin Z, Zeng X, Zang Y, Cheng X, Xiao H, Chen S, Lin M, Wang G, Peng J, Xiao Y, Qin J
Cancer cell 2026 Mar 9;44(3):658-675.e12

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Royal jelly protein hydrolysates accelerate in vitro diabetic wound healing by enhancing keratinocytes functions and suppressing macrophage-mediated inflammation.

Lin T, Huang L, Lin A, Yuan Y, Cai R, Lin Z, Wang L, Lin Y, Su S
BMC complementary medicine and therapies 2026 Mar 9;26(1)

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Inhibition of PRMT5 triggers synthetic lethality in ARID1A-deficient endometrial cancer by promoting aberrant R-loop accumulation.

Shu W, Dong K, Shen X, Zhou X, Zhang J, Yu S, Cheng S, Zhang T, Chen G, Zhong G, Zhang J, Wang H
Molecular cancer 2026 Mar 9;25(1)

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Integrated Proteomics and Metabolomics Reveal the Direct Hepatic Protection of Propionate Against Alcoholic Liver Disease via the RGN-PPARα Pathway.

Wang H, Liu H, Wang M, Chi T, Liu F, Qu X, Mu Y, Xu Q, Wang Q
Nutrients 2026 Mar 9;18(5)

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Epilepsy-associated FOXJ3 variants link a transcriptional program of the PTEN-mTOR pathway to neuronal specification and cortical lamination.

Cheng HY, Liu C, Nien CW, Huang HC, Zhao HJ, Nian FS, Chen C, Custodio HM, Sisodiya SM, Lu C, Chen HH, Hsu CS, Pi WC, Chu CC, Hsu JS, Chen PL, Chang FP, Tung CY, Chou SJ, Alavi S, Houlden H, Chen WY, Liu YT, Hou PS, Tsai JW
Nature communications 2026 Mar 9;17(1)

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NPM3 functions as a lactyltransferase to promote necroptosis in male diabetic cardiomyopathy mice models via FASN transcription modulation.

Xu H, Jiang X, Wang F, Meng F, Liu Y, Huang J, Li J, Zhu M
Nature communications 2026 Mar 9;17(1)

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Reduced osteogenic factors and early osteoblast senescence in SOD1(G93A) ALS mouse model.

Özkan B, Ramge JM, Wiesner D, Scekic-Zahirovic J, Antonucci S, Nungeß S, Gebauer D, Ignatius A, Weishaupt JH, Haffner-Luntzer M, Roselli F
JCI insight 2026 Mar 9;11(5)

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Inhibition of CDC20 suppresses the development and progression of mantle cell lymphoma through PI3K/AKT pathway.

Chen Y, Yang P, Gao S, Liu S, Wang J, Zhang W, Jing H
Annals of hematology 2026 Mar 9;105(4)

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A novel triaptosis-related prognostic signature to assess the clinical value in HER2-low breast cancer: evidence from clinical cohorts and experimental validation.

Liu J, Guan X, Dou M, Shi M, Yuan P
Apoptosis : an international journal on programmed cell death 2026 Mar 7;31(3)

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Deficiency of interleukin-40 prevents intestinal damage in experimental necrotizing enterocolitis by inhibiting NETosis.

Zhang Y, Ye C, Zhong X, Ding X, Yang Y, Ma Y, Guo C
Cell communication and signaling : CCS 2026 Mar 7;24(1)

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SCN5A (c.4720G> A): a rare genetic variant associated with familial sick sinus syndrome and sudden cardiac death.

Sheng M, Zheng H, Zhang L, Li K, Han X, Yu Y, Yu Y, Zhao S, Chen P, Qian W, Wang J, Wang K, Chen F
International journal of legal medicine 2026 Mar 7;

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ELAPOR1 mediated vesicle traffic is required for acrosome biogenesis and male fertility in mice.

Ding R, Guo Q, Wang L, Tang N, Fang X, Xin Z, Zhao W, Liu Y
Cellular and molecular life sciences : CMLS 2026 Mar 6;83(1)

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Plasma-activated hydrogel promotes postoperative colonic anastomotic leak healing.

Deng X, Ren K, Min T, Ma Y, Peng Y, Wang S, Zhang B, Xie X, Nan Y, Tong S, Liu Y, Zhang Y, Li K, Wang W, Hao N, Zhang G, Dang C, Sun T, Zhu K, Zhang H
Journal of advanced research 2026 Mar 6;

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Trolline attenuates diabetic vascular injury by regulating SLC7A11-mediated ferroptosis and mitochondrial dysfunction.

Liu W, Lu C, Yang B, Liu Y, Yan J, Song T, Wang X
Gene 2026 Mar 5;981:149968

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Phillyrin improves pulmonary epithelial barrier dysfunction in LPS-induced acute lung injury through the RhoA/ROCK signaling pathway.

Wang Y, Wu Q, Li L, Ke Y, Zhuang Y, Cheng B, Huang M, Wang Y
The Journal of pharmacy and pharmacology 2026 Mar 5;78(3)

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Curcumin protects against difenoconazole-induced kidney injury in carp by inhibiting ferroptosis through the Nrf2/GPX4 axis.

Zhang S, Li X, Gao Y, Dong Q, Jin X, Shi P, Dong J
Fish physiology and biochemistry 2026 Mar 5;52(2)

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Red Blood Cell-Derived Exosomes Deliver Complement C5 to Exacerbate Neuroinflammation and Neuronal Injury after Intracerebral Hemorrhage.

Chen Q, Min J, Lu X, Gao Z, Xiong Y
Inflammation 2026 Mar 5;49(1)

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Complement protein C1q induces endothelial apoptosis through C1qBP regulation of mitochondrial function in lung endothelial cells in systemic sclerosis.

Yi Z, Liu K, Shabin M
Molecular medicine (Cambridge, Mass.) 2026 Mar 5;32(1)

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PABPC1 regulates EOPE pathogenesis through modulating TMBIM4 mRNA expression and stability.

Zhao S, Lv N, Liu T, Sun Y, Li P
European journal of medical research 2026 Mar 5;

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Palmitoylation Induced Activation of SMAD3 Exacerbates Colitis by Promoting Tissue-resident Memory T Cells Differentiation.

Xu Y, Ji S, Jiang P, Zhao Z, Zhou Q, Su D, Ullah S, Zhao Y, Zou X, Zhang M, Sun J, Xu G, Tang J
Inflammation 2026 Mar 4;49(1)

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TFAP2A regulates SGPP2 transcription to promote lipid accumulation and activate the Wnt/β-catenin signaling pathway to promote malignant progression in lung adenocarcinoma.

Li Q, Li J, Zhang C, Deng Y, Yang B, Ma L, Liu Y, Wang C, Xu L, Mei J
Journal of translational medicine 2026 Mar 4;24(1)

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Yixinshu attenuates myocardial infarction via SHP1/JAK2/STAT3-mediated regulation of mitochondrial function and apoptosis.

Wang X, Wang X, Liu Y, Cui Y, Chen K, Wu H, Zhang M, Liao M, Fu L, Shen X
Chinese medicine 2026 Mar 4;21(1)

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ZG16 represses tumor progression and M2 polarization of tumor-associated macrophages in hepatocellular carcinoma by promoting ubiquitination and degradation of SNX9 via binding to ITCH.

Meng H, Wang Z, Wang L, Fang X, Li H, Ma W, Ding Y, Nan M, Meng Y, Li L, Li Y, Chen K, Zhang M
Hepatology international 2026 Mar 4;

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GR/HDAC3 Regulates Npas4 Signaling Pathway and Mediates Cognitive Impairment in Prenatal Hypoxia Male Offspring.

Zhao Z, Song Y, Yu X, Gao Q, Wang B, Sun M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 31;40(6):e71680

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Neural APLNR Deficiency-Induced Anxiety-Like Behaviors Associate with the Alteration of Global Gene Expression.

Wang X, Zheng H, Chen S, Zhao K, Li M, Cai Z, Bao G, Wu Y, Song W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 31;40(6):e71678

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Vericiguat Attenuates Post-Myocardial Infarction Inflammation Associated With Macrophage Polarization and Regulation of the Survivin/Caspase-6 Pathway.

Zhao Y, Li H, Wu Z, Yin Y, Wang H, Zhang L, Zhang Y, Jiang B, Jiang T, Li H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 31;40(6):e71635

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Integrated multi-omics analysis and functional validation reveal the role of TRIM2 as a potential novel biomarker in breast cancer.

Deng R, Ren Y, Hu K, Zhang Y, Xu Y, Zhang Q, Li Y, Huang X, Zhang F
Breast cancer research : BCR 2026 Mar 31;28(1)

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Lactiplantibacillus pentosus JWN01 and Lactiplantibacillus plantarum JWN02 attenuate renal fibrosis and pathological autophagy in hyperuricemic nephropathy via gut-kidney axis.

Mo Q, Qin M, Liang H, Wei L, Li Y, Qin Y, Tang L, Liang J, Qian C, Liang Y, Luo S, Wei Y, Kong L, Cheng J
Food research international (Ottawa, Ont.) 2026 Mar 31;228:118376

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Loss-of-function variants in ODAD1 disrupt ODA docking and induce actin cytoskeletal remodeling in primary ciliary dyskinesia.

Huo C, Luo T, Yang S, Jiang Y, Guo M, Yang F, Xu Z, Xia J, Wu L, Xu W, Gui M, Zhou T, Xie S
Cell discovery 2026 Mar 31;12(1)

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Arsenic Inhibits the PA28α/β-PSMB5 Pathway Blocking Phosphorylated TFEB Degradation and Causing Lysosomal Dysfunction that Damages the Liver.

Lv Y, Wang H, Wang T, Qin Y, Bi D, Zhi H, Du C, Peng J, Zhang J, Hu Y
Biological trace element research 2026 Mar 31;

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P2X7 receptor-mediated cGAS-STING pathway activation underlies chronic stress-induced depressive-like behaviors.

He XM, Zhang Y, Chen CY, Tang YH, Li X
Purinergic signalling 2026 Mar 30;22(2)

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Disruption of sphingolipid metabolism triggers lung vascular inflammation and aging-like changes under hypoxia through VDAC1-mediated mitochondrial DNA release.

Xu J, Ge Y, Zhang B, He S, Cao Q, Li P, Bu Y, Bai Y, Zhang L, Tan G, Ma J, Xie M
Apoptosis : an international journal on programmed cell death 2026 Mar 3;31(3)

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Glucose metabolism sustains aberrant STAT3 signaling in colorectal cancer through glycosylated local signaling factors.

Buscher K, Temprine K, Mays C, Aabed N, Kerk SA, Bell HN, Nieto Carrion JA, S Greenbaum H, Lee ZH, Ponnusamy V, Ramakrishnan SK, Lyssiotis CA, Xue X, Shah YM
Science signaling 2026 Mar 3;19(927):eadz6443

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Multi-omics analysis of NEDD1 in hepatocellular carcinoma: biological function, prognostic value, and clinical significance.

Chen Y, Wan Z, Xie H, Zhou X, Peng T
Scientific reports 2026 Mar 3;16(1)

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Development of recombinant fowl adenovirus serotype 4 harboring the HiBiT-Tag reporter and its utility in antiviral research.

Guo X, Li C, Meng L, Li X, Li F, Wang L, Dong Z, Zhu Q, Sun H, Zhang L, Yan M
Microbiology spectrum 2026 Mar 3;14(3):e0334725

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The segmented flavivirus ALSV-encoded nucleoprotein VP2 inhibits type I interferon production by targeting RIG-I.

Pan M, Song Z, Wang M, Zhao M, Fang S, Jin F, Tan Q, Xu W, Che L, Liu N, Sui L, Liu Q, Hou Z, Zhao Y
Microbiology spectrum 2026 Mar 3;14(3):e0248425

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DUSP4 mitigates doxorubicin-induced cardiotoxicity via the p38 MAPK/MK2 signaling pathway.

Deng L, Zha Y, Zhu C, Li Y, He M, Zhang S
Biochimica et biophysica acta. Molecular cell research 2026 Mar 29;1873(5):120141

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DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling-Mediated Anti-tumor Immunity.

Huang K, Dai X, Li S, Chen Y, Yu Y, Wang L, Liu K, Lyu S, Li C, Sun Y, Li F
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 29;:e17634

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FXR overexpression promotes liver regeneration through inducing FGF2 activation in APAP-induced acute liver injury.

Wang R, Chen J, Wang W, Li X, Xiao Y, Shi Y, Qv Y, Wang C, Fu T, Meng Q
Hepatology international 2026 Mar 29;

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Metformin attenuates HSV-1-induced neuropathic pain by restoring Sirt3-mediated mitophagy.

Fang Y, Deng M, Huang K, Song H, Chu Y, Wei H, Chen D, Yang Y, Han C, Yuan H
Cell communication and signaling : CCS 2026 Mar 28;24(1)

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Overcoming lysosomal barrier via V-ATPase: an exosome-based co-delivery platform for combined chemo/RNAi therapy against breast cancer.

Liu K, Xiong T, Wang X, Wang T, Wang Y, Lei M, Shao L, Zhang L, Zhu Y
Journal of nanobiotechnology 2026 Mar 28;24(1)

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TNF-α impairs the stria vascularis by inducing pericyte apoptosis via the NF-κB pathway in gentamicin-induced hearing loss.

Li G, Chen G, Hu R, Zeng J, Liu P, Liang M, Zheng Y
Journal of neuroinflammation 2026 Mar 28;23(1)

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Loganic Acid Ameliorates Rheumatoid Arthritis via the Lactobacillus murinus-Inodole-3-Acetic Acid-AhR-IL-10 Axis.

Tan W, Fu Y, Hu W, Lin Y, Cai J, Huang X, OuYang Y, Lin S, Ye L
Phytotherapy research : PTR 2026 Mar 28;

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Mitochondrial ATP production promotes T cell differentiation and function by regulating chromatin accessibility.

Ng C, Fung TS, Li D, Kropp KN, Somarribas Patterson LF, Markovitz A, Weinberg DN, Jones O, Kim JY, Zhang G, Koche R, Monetti M, Tang H, He Y, Xu Z, Cai X, Yu Z, Bhagavatula G, Colgan SP, Lin YH, Li Z, Steinert EM, Klebanoff CA, Vardhana SA, Chandel NS, Wu L, Thompson CB
bioRxiv : the preprint server for biology 2026 Mar 28;

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STUB1-VCP/p97 complex regulates mitophagy via fine-tuning of PINK1 levels.

Lin JY, Huang ZB, Zhang SQ, Wu Y, Cheng LJ, Gao X, Lautrup S, Cao SQ, Pan J, Rong D, Ai R, Weng Siong Tan H, Wang L, Wang H, Shen HM, Fang EF, Lu G
Cell reports 2026 Mar 27;45(4):117183

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WFS1-related isolated diabetes induced by a WFS1 missense mutation: focus on the isolated diabetes phenotype.

Huang M, Wei Q, Qin Y, Qin L, Shao Y, Wang S, Qu X, Yang T, Zhang M
Orphanet journal of rare diseases 2026 Mar 27;21(1)

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CircIQGAP1-CARM1 axis promotes renal cell carcinoma progression through glycolytic reprogramming.

Jia R, Zou B, Liang Y, Chen Q, Chen T, Li X, Zhang C, Pei F, Zhu X, Bian J, Guo R
Cell death & disease 2026 Mar 27;17(1)

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Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and Ferroptosis.

Yuan S, Wei N, Ma W, Hu M, Zhang B, Gao L, Gao C, Yang X, Meng Y, Liu J, Cui Y
Andrology 2026 Mar 27;

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Short-chain acyl-CoA dehydrogenase initiates mtDNA demethylation and leakage to fuel antitumor immunity in colorectal cancer.

Yang F, Wang M, Hu S, Guan X, Zhao K, Zhou Y, Yao H, Zhang T, Li L, Gao Y, Zhao S, Liu N, Xiao W, Xiang Y, Miao H
Signal transduction and targeted therapy 2026 Mar 26;11(1)

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HSYA attenuates Inflammation - Necroptosis to ameliorate secondary brain injury after intracerebral hemorrhage.

Luo L, Ma Q, Liao Y, Xiang M, Gao X, Li Z, Yan S, Zhou D, Su Q
Journal of ethnopharmacology 2026 Mar 25;359:121097

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AIBP deficiency drives MAFLD advancement via ITGβ3 mediated lipid metabolism disruption and pro-inflammatory activation.

Deng W, Yang X, Wu H, Tang H, Wang X, Tu S, Yin K, Zhu X
Cell communication and signaling : CCS 2026 Mar 25;24(1)

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A new candidate tumor suppressor tRF-Ser inhibits gastric cancer progression by regulating the CNBP/HSPA8 axis.

Jiao J, Wang G, Liu J, Xiao K, Gao Z, Dong D, Shan K, Cui H, Shang L, Li L, Zhang C
Cell death & disease 2026 Mar 25;17(1)

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Myeloid-Derived Grancalcin Promotes Periodontal Inflammation and Pathological Bone Remodeling in Periodontitis.

Zhou M, Xiao Y, Xu Z, Yang C, Li J, Liu Y, Yin P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 25;:e19267

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Acid Ceramidase Inhibition Disrupts Ceramide Homeostasis and Induces Mitochondrial Apoptosis in IDH1-Mutant Oligodendroglioma.

Larion M, Muley H, Zaibaq F, Zhang M, Davis D, Kruhlak M, Mathur S, Lita A, Song H, Zhang W, Wong Z, Harmon T, Zhang L, Cam-El Makranz C, Li A, Karadimov G, Lang F, Herold-Mende C, Yang C, Dowdy T
Research square 2026 Mar 25;

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SETDB2-mediated transcriptional repression of IDE in sensory neurons promotes migraine-like pain behaviors in mice.

Zhang Y, Huang Z, Sun Y, Wang S, Tao Y, Lu W, Zhang Y, Jiang D, Ge J, Chen G, Jin X, Ji F, Wang Y, Yu Y, Zhang Y, Tao J
Cell reports 2026 Mar 24;45(4):117201

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TCR-NF-κB signaling activates the SENP1-NR4A1 axis to fine-tune effector activation of CD8(+) T cells.

Jiang C, Yang Y, Tian J, Liang Z, Fan Q, Wang Q, Shen L, Wang S, He J, Cheng J
Cell reports 2026 Mar 24;45(3):117102

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IFITM1-targeted NIR-II fluorescence imaging enables visualisation of colorectal cancer and metastatic lymph nodes.

Jin S, Lin R, Guan S, Jiang J, He H, Wei E, Lv Z, Yang W, Huang J, Zheng S, Zhou Z, Ge R, Jia X, Yang C
Journal of translational medicine 2026 Mar 24;24(1)

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Engineered Bacteria-Driven Biohybrid Microrobots Potentiate IL-2 Immunotherapy by Evoking Pyroptosis.

Li P, Li Q, Ding L, Peng S, Wei H, Chen T, Xiong Y, Tang BZ, Huang X
ACS nano 2026 Mar 24;20(11):9407-9427

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Microglial PRMT2IP alleviates ischemia-induced brain injury.

Zhang M, Cai J, Su W, Zeng Q, Zhang H, Deng J, Zhai B, Xiao H, Zhu G, Gao R, Qiu J, Bian Z, Luan G, Wang R
Brain, behavior, and immunity 2026 Mar 24;136:106558

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Glycosylated NS3/NS3A protein of bluetongue virus facilitates efficient viral egress via lipid raft anchoring.

Huang Y, Qi Y, Guan J, Shao R, Xi C, Liu X, Zhou D, Qi S, Yin X
Journal of virology 2026 Mar 24;100(3):e0214425

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The ASFV CD2v protein inhibits apoptosis by inducing proteasomal degradation of Bim(EL) via activation of the TPL2-MEK-ERK signaling pathway.

Zeng J, Zhang X, Zhao J, Li Q, Xiang Z, Shi F, Wang H, Weng W, Zhou Q, Gao P, Zhou L, Ge X, Han J, Guo X, Zhang Y, Yang H
Journal of virology 2026 Mar 24;100(3):e0195225

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Decorin inhibits the migration and invasion of the LPS + high glucose-induced primary trophoblast cell through ADAMTS12.

Chen Q, Hu T, Luo H
In vitro cellular & developmental biology. Animal 2026 Mar 24;

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Heparan sulfate as an attachment factor for ASFV is restricted by host HB-EGF.

Xue W, Yang F, Zhang Z, Zhang X, Yang Y, Li Y, Feng Z, Li Y, Lan X, Zheng H, Zhu Z, Zhang S
Cellular and molecular life sciences : CMLS 2026 Mar 23;83(1)

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Baicalin Augments 5-Fluorouracil Efficacy in Colorectal Cancer by Triggering MLKL-Dependent Necroptosis: A Novel Strategy to Overcome Chemoresistance.

Yuan J, Peng Z, Wen R, Zhou L, Cao F, Zhang T, Wu Y, Wu J, Lin R, Yu G, Zhang W
International journal of molecular sciences 2026 Mar 23;27(6)

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MEG3 in glioma stem cells promotes glioblastoma angiogenesis through FUBP3-mediated VGF expression.

Li Y, Li Y, Tang J, Kong X, Sun S, Wang W, Wu H
Clinical and experimental medicine 2026 Mar 23;26(1)

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Extracellular vesicles derived from live or apoptotic mesenchymal stem cells: comparison of the effects of two extracellular vesicles on liver fibrosis.

Ju R, Tian S, Li B, Zhang M, Ma S, Hu Y, Su R, Yang F, Xia E, Shang Y, Zhou X, Han Y
BMC gastroenterology 2026 Mar 23;26(1)

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The APC/C subunit APC7 promotes hepatocellular carcinoma progression by mediating ubiquitination and degradation of LATS1 to activate YAP/TAZ.

Sun Y, Zhang R, Guo Y, Wu D, Wei H, Tan Z, Huang M, Wang Y, Fang Z, Zhang C, Li C, Li W, Wei D, Bian H, Liu ZK
Biology direct 2026 Mar 23;21(1)

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Dual targeting of PI3Kδ and PPARα enhances antitumor activity via FoxO1 activation in follicular lymphoma.

Wang W, Zhou H, Tan S, Qin D, Wang S, Xu C, Lei X, Li W, Wang L, Fu S, Jia S, Xu B, Zha J
Cell death & disease 2026 Mar 23;17(1)

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Monosodium Glutamate Inhibits Pseudomonas aeruginosa-Induced Acute Lung Injury by Targeting the Type III Secretion Systems and Modulating Host Immunity.

Xu J, Wang W, Zhou Y, Zhang H, Shang Z, Zhang Z, Li B, Bai Y, Zhang J
Microorganisms 2026 Mar 23;14(3)

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PEAR1/EAF1 deficiency impairs aspirin responsiveness in atherosclerotic endothelium: A novel mechanism of atypical aspirin resistance.

Liu J, Peng J, Zhan Y, Liu L, Xu K, Xie Y
Microvascular research 2026 Mar 23;:104946

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Integrated stress response inhibition rescues inflammation-associated accelerated forgetting of recognition memory in mice.

Liu SY, Zuo Y, Jin X, Kuang X, Tian SW
Psychopharmacology 2026 Mar 23;

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Elevation of H(2)S Underlies Social Deficits in Environmental Factor Double-Hit Autism Model.

Ma H, Xu Q, Dong S, Guo M, Liu H, Wang T, Wang M, Wang Y, Wu S
Neuroscience bulletin 2026 Mar 23;

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Loss of Lamp2a-dependent chaperone-mediated autophagy drives dry AMD-like retinal pathology in mice and is rescued by BK channel activation.

Mir HA, Mahesh G, Palanimuthu A, Cioffi CL, Petrukhin K
bioRxiv : the preprint server for biology 2026 Mar 23;

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TRIM21-Mediated ubiquitination of FBL suppresses PI3K/AKT signaling and tumor progression in clear cell renal cell carcinoma.

Guan B, Tang H, Yuan Z, Yao J, Cui D, Hao Z, Li X
Cellular and molecular life sciences : CMLS 2026 Mar 21;83(1)

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[Different Astragalus medicinal pairs improve diabetic nephropathy in mice by regulating lipid peroxidation through PTGS2].

Chen X, Jing Y, Liang H, Zhong J, Chen Z, Peng Y, Dai J, Xiao Y
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2026 Mar 20;46(3):592-603

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USP1 promotes hepatocellular carcinoma progression by modulating mitophagy via stabilizing MCM3 to regulate the Keap1-Nrf2 axis.

Chen Z, Sun C, Wang Y, Duan X, Ma H, Zhou X, Chen S, Peng P
iScience 2026 Mar 20;29(3):114927

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USP5-mediated CD73 deubiquitination drives osimertinib resistance via PI3K/AKT and glycolysis activation in LUAD.

Chen R, Han XH, Zhang Z, Han XJ, Xie J
iScience 2026 Mar 20;29(3):114916

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YBX1 promotes angiogenesis after myocardial infarction by stabilizing HIF1α mRNA via m(6)A signaling.

Bi F, Yu T, Liu H, Cao M, He Y, Li J, Wang H, Kong C, Xiao H, Tian H, Liu F, Wu Y, Zhou Y, Shan H
iScience 2026 Mar 20;29(3):114810

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Single-cell multiomics uncovers an endothelial mechanosensitive PIEZO1-IL-33 axis driving pulmonary fibrosis.

Zhang L, Gui X, Hou R, Jia L, Xia S, Zhang X, Fu Y, Meng QF, Luo Q, Shi X, Guo B, Liang R, Yue L, Chen X, Xu H, Wang P, Tong X, Liu L, Wang L, Li B, Chen Z, Zhou L, Zhang L, Chen R, Sun C, Xu W, Rao L, Zhou H, Ding BS, Chen S
Nature communications 2026 Mar 20;17(1)

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ARHGDIB Modulates Subcutaneous Fat Deposition in Ducks.

Wang M, Zheng H, Chen X, Zhou A
Animals : an open access journal from MDPI 2026 Mar 20;16(6)

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The sulfonamide anticancer agent indisulam enhances the chemosensitivity of gastric cancer cells by targeting FKBP8.

Li Y, Lu C, Lu J, Jiang H, Li D, Wang Y, Xu G, Wang X, Ma J
The FEBS journal 2026 Mar 20;

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ZNF219 inhibits porcine epidemic diarrhea virus by degrading viral S2 protein.

Zhao W, Kong N, Lan D, Zhang Y, Liu H, Liu C, Qin W, Yang X, Liu T, Tong W, Yu H, Zheng H, Tong G, Xie S, Xing G, Shan T
Virologica Sinica 2026 Mar 20;

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A Cross-Species Hydroquinone Model Replicates Smoking-Related Corneal Endothelial Oxidative Injury and Enables Therapeutic Screening of FGF10.

Lee BJ, Agarwal D, Huang JH, Ivanova A, Bu JJ, Hill CA, Noguchi T, Jun JH, Makarenkova HP, Wahlin KJ, Shaw PX, Afshari NA
Investigative ophthalmology & visual science 2026 Mar 2;67(3):12

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High COMP expression promotes tumor cell proliferation and migration of rectal cancer, contributing to unfavorable prognosis and suppressive immune microenvironment.

Shang J, Sheng WJ, Jia HZ, Wang D, Yang DZ
Discover oncology 2026 Mar 2;17(1)

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Biglycan knockdown improves Graves' orbitopathy (GO)-like features via inhibiting NF-kB and ERK signaling.

Chenzhao C, Zhu M, Zhang F, Xie B, Cao J, Xiong W, Tan Y
Journal of endocrinological investigation 2026 Mar 2;

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A Novel Insight into Chronic Pancreatitis Pathogenesis: the USP1/ITGB5 Axis-Mediated Stellate Cell Activation.

Wang D, Shi Y, Lu J, Bao W, Wang N, Shen Q, Lin Z, Qian L, Zhu C
Inflammation 2026 Mar 19;49(1)

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TCF7L2/DEPDC1 axis contributes to tumor progression by promoting cell proliferation, aerobic glycolysis, and immunosuppression in pancreatic cancer.

Tasiheng Y, Kenjiabieke J, Tasiheng N, Adilijiang K, Cheng H
Clinical and experimental medicine 2026 Mar 19;26(1)

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Multi-omics analysis and experimental validation uncovers prognosis significance of IKBIP in patients with hepatocellular carcinoma: a multicenter cohort study.

Jiao Y, Guo L, Lu Y, Li M, Zhong Y, Wu B, Dong H, Wang T, Chen E
BMC gastroenterology 2026 Mar 19;26(1)

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Nobiletin enhances Doxorubicin sensitivity in osteosarcoma through ER stress-induced apoptosis mediated by the PI3K/AKT pathway.

Liu F, Yuan D, Zhang Z, Gong R, Jin X, Wang C, Xie W, Zhang Y
Scientific reports 2026 Mar 19;16(1)

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Ferulic Acid Alleviates Chemotherapy-Induced POI by Targeting the Grp78 and Perk-eIF2α-ATF4-CHOP Pathway to Attenuate Endoplasmic Reticulum Stress.

Li F, Huang Y, Liu Z, Geng Y, Hu R, Song Y, Xu L, Zhang M
Biomedicines 2026 Mar 19;14(3)

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Zearalenone Disrupts the Placental Barrier via Integrated Stress Response Activation in Mice and Human Trophoblast Cells.

Wu FN, Liu JR, Qing YY, Sun ZX, Tian Z, Chen C, Liu KX, Lin S, Hong Q, Fan YJ, Chen YH
Journal of agricultural and food chemistry 2026 Mar 18;74(10):8671-8686

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Clinical and Functional Characterization of Novel GALNT3 Mutations in a Chinese Child with Hyperphosphatemic Familial Tumoral Calcinosis.

Gao Y, Zhang C, Wu S, Ying Y, Hou L, Liang Y, Luo X
International journal of molecular sciences 2026 Mar 18;27(6)

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The GAP43/RAC1 axis drives glycolytic reprogramming and progression in lung adenocarcinoma.

Li K, Shen C, Li Y, Zhang Q, Guo J
Respiratory research 2026 Mar 18;27(1)

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RNF213 Is an Interferon-Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection.

Li H, Zhang Y, Wang J, Zhang Q, Sun H, Wei F
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 18;:e11012

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Comprehensively exploring the roles of MAGEA1 in cryptorchidism and its related transcription factor regulatory network.

Chen J, Shen D, Kong J, Zhang Y, Ge W, Xian H
Journal of molecular histology 2026 Mar 17;57(2)

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Adipose tissue-derived stromal cells enhance glycolytic metabolism in injured nerve cells via the FOXK1-HK2 axis for spinal cord injury repair.

Li F, Li H, Jia Y, Ou L, Fang Y, Pan L, Liu H, Ning B
Journal of translational medicine 2026 Mar 17;24(1)

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Single-Atom Nanozyme Driven Lactate Reversal Fuels Oxidative Metabolism and Represses Lactylation to Heal Diabetic Wounds.

Wu W, Zhou H, Zhang M, Zhang X, Huang M, Tao S, Du W, Wang S, Zhao J, Zhou X, Liu N, Chen T
ACS nano 2026 Mar 17;20(10):8548-8569

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Kynurenine promotes porcine intestinal epithelial cell proliferation by activating the AHR-MST1-YAP1 axis.

Hu Z, Yin L, Wang Q, Deng J, Zhu X, Yang H, Zhang P, Yin Y, Tang X
Journal of animal science and biotechnology 2026 Mar 17;17(1)

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Hedyotis diffusa and Scutellaria barbata enhance the anti-ovarian cancer effect of cisplatin through network pharmacology analysis and molecular docking technology.

Bi R, Chen F, Fu Y, Guo C, Li W
Scientific reports 2026 Mar 17;16(1)

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Integrative Transcriptomics and Machine Learning Reveal the Association of CBX4 with Inflammation in Ulcerative Colitis as a Potential Epigenetic Regulator.

Ma X, Liu G, Gong T, Liu X
Biomedicines 2026 Mar 17;14(3)

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Inosine promotes erythrocyte metabolic reprogramming and restores oxygen release for rejuvenation via 2,3-BPG-PNP axis.

Liu W, Yang Z, Chen C, Yu F, Wu M, Yao Z, Fan Y, Xie T, Wan L, Chou T, Feng X, Qi H, Chou Y, Zhao J, Liu J, Yang Z, Zhang Y, Kellems RE, Xia Y
Cell discovery 2026 Mar 17;12(1)

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B3GNT3 facilitates NFKB2 processing and non-canonical NF-κB activation to drive lung adenocarcinoma progression.

Lin Y, Zhang Y, Yu B, Wang J, Wu Z, Wang H
Cellular oncology (Dordrecht, Netherlands) 2026 Mar 16;49(2)

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Ginsenoside Rh4 Triggers Ferroptosis in Lung Cancer: Targeting KEAP1/NRF2/HO-1 and Remodeling Gut Microbiota for Butyrate-Mediated ATF3 Activation.

Zhu Q, Xu W, Yang G, Gao Y, Zhao Y, Zhao Z, Kang Y, Li S, Zhao L
International journal of molecular sciences 2026 Mar 16;27(6)

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Study on the effects and mechanisms of M2 macrophages on PYCR1-promoted biological behavior of hepatocellular carcinoma cells.

Jin X, Hou Y, Guo J, Zhang J, Wu W
Scientific reports 2026 Mar 16;16(1)

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tLyP-1 peptide-modified MnO₂ co-delivering si-SLC16A1 and temozolomide synergistically suppresses glioblastoma via hypoxia modulation and metabolic stress.

Zhao H, Meng L, Du P, Chen Y, Gong M, Zan B, Chen J, Zeng M, Liao Y
Journal of nanobiotechnology 2026 Mar 16;

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Bisphenol A disrupts circadian locomotor rhythms via m(6)A-dependent nr1d1 destabilization in zebrafish larvae.

Kong WY, Chen PY, Shen O, Cai YN, Liu WX, Li XJ, Lu SZ, Bian W, Wang H, Wang YH, Wu LJ, Ji C, Song XY, Zhang J
Ecotoxicology and environmental safety 2026 Mar 15;313:119887

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Probiotic Gordonia alkanivorans Enhances Phagocytic Function of Porcine Alveolar Macrophages and Modulates Immune Responses in Piglets.

Lu X, Wu J, Zhang Z, Li X, Liu Z, Liu G, Wang G
Veterinary sciences 2026 Mar 15;13(3)

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Protective Effect of Gastrodia elata Polysaccharide GEP-2 Against Oxidative Stress in Intestinal Epithelial NCM460 Cells.

Yao Y, Wen X, He X, Liao D, Li M, Fan J, Liang R, Huang X, Li N
International journal of molecular sciences 2026 Mar 14;27(6)

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Germacrone suppresses renal cancer growth by regulating c-Fos-mediated lipid metabolism.

Wang B, Zhang R, Wu M, Cai T, Gao C, Wang L, Jin T, Xu Z, Jin J, He Q
Lipids in health and disease 2026 Mar 14;25(1)

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CD93-targeted resveratrol-loaded PLGA nanoparticles remodel CD8⁺ T cell metabolism through AIF-mediated oxidative phosphorylation to overcome lung cancer immunotherapy resistance.

Jiang Z, Li Y
Journal of nanobiotechnology 2026 Mar 14;24(1)

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Fibroblast-derived exosomes induce macrophage pyroptosis to mediate orthodontic bone remodeling through the mtDNA/NLRP3 axis.

Yu Q, Guo K, Yang Y, Liu H, Han Y, Yu X, Wang J, Zhao Y, Su X, Zhu K, Zheng S, Wang S, Li W, Huang Y
Journal of nanobiotechnology 2026 Mar 14;24(1)

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Mitophagy Activation via the YAP/Parkin Pathway Underlies the Neuroprotective Action of Tetramethylpyrazine in Cerebral Ischemia/Reperfusion Injury.

Xu L, Wang M, Feng Y, Wang S, Qian Y, Jiang W, Xu J, Fang Y, Zhang Y, Chu L
Biomolecules 2026 Mar 13;16(3)

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Alkaloids from Evodia rutaecarpa inhibit the occurrence and development of gallbladder cancer in vivo and in vitro.

Li Y, Zhou S, Xu H, Zhou H, Sun K, Hu S, Xu K, Yang J, Chen Y, Li W
Scientific reports 2026 Mar 13;16(1)

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Suppression of LTBP1 enhances the sensitivity of bladder cancer to cisplatin.

Li Z, Yu Y, Liu F, Wu Y, Zang Y, Ding Y, Zhang Z
Scientific reports 2026 Mar 13;16(1)

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Mapping Genetic Regulation of Transcription to Identify Functional Variants and Genes Associated with Pancreatic Cancer Risk.

Wang X, Geng H, Yao Z, Jiang Y, Chen C, Lu Z, Tian S, Zhang M, Liu R, Feng C, Li B, Miao X, Tian J, Zhang S, Zhu Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 13;:e17184

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Role of glutamine in promoting the proliferation and chondrogenic differentiation of ATDC5 cells: based on transcriptomic analysis.

Zhang RH, Yuan WH, Wang ZL, Yang QR, Sun Y, Shao QN, Wang WJ, Wang J
Molecular biology reports 2026 Mar 12;53(1)

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Rabies lyssavirus phosphoprotein possesses RNA duplex-unwinding activities.

Mu J, Wang C, Shu T, Xiong X, Ren Y, Gong R, Zhao L, Zhou X
Molecular therapy. Nucleic acids 2026 Mar 12;37(1):102863

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Design, synthesis and biological assessment of erlotinib-1,2,3-triazole derivatives for anticancer applications.

Yao Q, Qu K, Wang L, Huang M, Mao L, Li S
RSC medicinal chemistry 2026 Mar 12;17(4):2053-66

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ANGPTL2 inhibits macrophage pyroptosis and alleviates rheumatoid arthritis progression by regulating mitophagy via IGFBP5.

Liu Y, Yang Q, Huang Z, Sun J, Xiao J, Yang Z, Huang X, Ma L, Wang X, Wang C, Cao Z
Cell death & disease 2026 Mar 12;17(1)

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HIV-1 Nef induces astrocytes proliferation, inflammatory response, A1-like astrocytes polarization and subsequent neuronal apoptosis via NF-κB signaling pathway.

Zhang L, Yao H, Tao W, Cao D, Gao L
Journal of neurovirology 2026 Mar 11;32(2)

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S100A11 regulates microglial inflammatory response in neuropathic pain via H3K27ac-TFEB-mitochondrial autophagy axis.

Zheng H, Tian S, Wu L, Jia G, Xiao Y, Yu X, Zuo Q, Zhou R, Min J, Wu Q, Xie H, Luo Q, Wu W
The journal of headache and pain 2026 Mar 11;27(1)

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PET-microplastics trigger endothelial glycocalyx loss via ER stress and ROS unleashing IL-1β-driven SMC switching and early aortic structural impairment.

Huo W, Qu J, Wang S, He M, Zeng Z, Kong D, Yuan L, Feng R
Journal of nanobiotechnology 2026 Mar 11;24(1)

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Oral Rhizoma Coptis Alkaloids Nanoparticle for Treating Diabetes Through Regulating PI3K/Akt Pathways.

Liu Y, Zhu M, Su Q, Liu M, Zhao Z, Ma P
Pharmaceutics 2026 Mar 11;18(3)

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Molecular insights into the regulation of GNPTαβ by LYSET.

Yang X, Doray B, Henn D, Venkatarangan V, Jennings BC, Dong Z, Liang J, Zhang W, Zhang B, Yu L, Chen L, Kornfeld S, Li M
Nature communications 2026 Mar 11;17(1)

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Dual roles of GDNF in enteric glial cell plasticity: direct transdifferentiation via the CaMKII/NeuroD1 pathway and cooperative regulation in a neural stem cell-inducing medium.

Jia W, Yan H, Huang J, Liu W, Fu Z, Tian D, Xu W, Chen X, Gao Y, Yu H
Stem cell research & therapy 2026 Mar 11;17(1)

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miR-223-3p improves macrophage polarization balance and mitochondrial metabolism to ameliorate uveitis by orchestrating P65(Lys310) acetylation through RBPJ/HDAC1 axis.

Peng Y, Liu B, Xu S, Qu R, Zhang R, Wang C, Liu Y, Wei H, Tian Q, Zhang M, Bi H, Yin X, Guo D
Cellular & molecular biology letters 2026 Mar 10;31(1)

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Labile iron pool dynamics do not drive ferroptosis in colorectal cancer cells.

Ponnusamy V, Randall DR, Lee ZH, Das NK, Zhao L, Buscher K, Solanki S, Renslo AR, Hsu PP, Shah YM
The Journal of biological chemistry 2026 Mar 10;302(5):111357

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Tumor-Directed Disulfidptosis via Spatiotemporally Controlled Copper Bioorthogonal Activation.

Yin Y, Yu W, Shen Z, Yuan S, Cao K, Liu HK, Liu Y
ACS nano 2026 Mar 10;20(9):7569-7588

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HIF3A-mediated aberrant activation of TXNIP promotes Alzheimer's disease progression.

Xue M, Zheng W, Li F, Gao L, Jia X, Pang S
Scientific reports 2026 Mar 10;16(1)

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AGPAT3 reshapes tumor cell vulnerability to IFNγ-mediated ferroptosis and enhances immunotherapy efficacy through lipid remodeling.

Liu C, Hu C, Cheng J, Xin D, Jin S, Tian W, Li S, Jin Y, Liu Y, Wu W, Hao S, Ren H, Dai X, Liu L, Ruan J, Fang W, Bao X, Xin S, Zhao P
Journal for immunotherapy of cancer 2026 Mar 10;14(3)

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TRMT6-directed m(1)A modification initiates lung squamous cell carcinoma via YTHDF3-stabilized cell cycle genes.

Xue W, Zhu L, Wei X, Sun J, Lin W, Huang S, Wu L, Zhang D
NPJ precision oncology 2026 Mar 10;10(1)

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Angiotensin II-Induced Ferroptosis in Epithelial Cells Contributes to Kidney Injury via SP1-DPEP1-Mediated SLC3A2 Degradation.

Tian Y, Yang G, Zhang Q, Dong C, Li Y, Lv S, Li S, Zhang H, Jiang X, Xin Y
Diabetes 2026 Mar 1;75(3):548-562

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Qiang-Xin 1 formula improves cardiac function and alleviates myocardial injury in lipopolysaccharide-induced septic mice by activating calcium/calmodulin-dependent protein kinase I-mediated mitophagy.

Huang P, Wang Q, Zhu Y, Hu X, Fang X, Deng W, Cao P, He S
Journal of ethnopharmacology 2026 Mar 1;358:121033

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Yishen Qianggu Mixture formulation suppresses osteometabolic inflammation by modulating the IL-17/NF-κB/MAPK signaling axis.

Zhao J, Peng GG, Xiao D, Fu CJ, Chen HZ, Luo SJ, Wu HQ, Huang M
Journal of ethnopharmacology 2026 Mar 1;358:121011

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Angelica sinensis polysaccharides prevents marrow cell apoptosis during stress via regulating endoplasmic reticulum-mitochondrion and adaptive metabolism.

Jiang H, Min C, Wang B, Wang Z, Sun N, Du K, Wang C, Huang C, Wang Y, Wang L
Journal of ethnopharmacology 2026 Mar 1;358:120968

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Total Extract of Folium Rhododendri Daurici alleviate MASLD by regulating PPAR and TNF signaling pathways.

Zhang Y, Yin Z, Zhang Y, Wei Y, Zhai Y, Zhao X, Zhan B, Wang Z, Feng H
Journal of ethnopharmacology 2026 Mar 1;358:120955

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Protective effect and mechanism of synagrantol A from Euphorbia pseudomollis on LPS-induced neuroinflammation.

Hu Q, Zhang D, Wang H, Chen K, Zhang F, Zhang X, Zhu YZ
Journal of ethnopharmacology 2026 Mar 1;358:120944

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Integrative network toxicology and single-cell transcriptomics reveal TP53 as a key mediator of PCBs-induced microglial dysfunction in diabetic retinopathy.

Zhou M, Huang X, Wang L, Zhou Y, Chen Z, Wang L
Ecotoxicology and environmental safety 2026 Mar 1;312:119946

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METTL3-mediated GLUD1 m6A Modification Promotes Hydrogen Peroxide-induced Mitochondrial Dysfunction in Human Nucleus Pulposus Cells Via the Glutamate/α-KG Metabolic Axis.

Bai M, Wu Y, Zhang Y, Zhang H, Wang P, Li S
Journal of musculoskeletal & neuronal interactions 2026 Mar 1;26(1):147-161

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circKANSL1 promotes immature porcine Sertoli cell growth via recruiting the Vimentin to enhance its parental gene KANSL1 expression.

Yan S, Weng B, Xiang J, Chen B, Ran M
Theriogenology 2026 Mar 1;252:117772

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α-lipoic acid nanoparticles functionalized with RVG29 peptide attenuate seizure-induced neurotoxicity by restoring mitochondrial homeostasis via the PINK1/Parkin pathway.

Hou J, Hao L, Du W, Su Q, Xiong Q, Zhao W, Yang Z
Free radical biology & medicine 2026 Mar 1;245:201-222

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Lipid deposition promotes YTHDF3-mediated m6A modification of PPARα to facilitate liver metastasis of colorectal cancer.

Ni W, Xu Y, Zhang M, Li Y, Huang P, Li Z, Wu Q, Mo H, Ye Y, Li Y, Zhou A, Yao S, Zhi S, Qi J, Yu S, He S, Li J
Protein & cell 2026 Mar 1;17(3):190-211

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Administration of Nicotinamide Mononucleotide Mitigates the HIV Nef-Induced Metabolic and Pathological Changes in the Heart.

Kondrachuk O, Nakhungu E, Ogundipe G, Tailor N, Ciccone P, Hong K, Gadiraju A, Kimura Y, Zi A, Yusuf S, Alkousa A, Nguyen S, Rajkumar R, Do J, Rappaport J, Gupta MK
Cells 2026 Mar 1;15(5)

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Butyrate protects against Klebsiella pneumoniae-induced oxidative stress in alveolar macrophages via p62-Keap1-Nrf2 pathway.

Meng B, Li H, Tang M, Zhu J, Yao R, Xu Y, Zhang Q, Zhu R, Guo Y, Xu Y, Shu Y, Yu L, Li Y, Yang Y, Liu Y, Wu T, Li J
Redox biology 2026 Jun;93:104156

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Integrative multi-omics analysis identifies key ubiquitination regulators in prostate cancer.

Wei H, Gong C, Tan Z, Yang E, Huang Y, An Y, Li H, Lv D, Yang C, Chen W, Wang H, Li S, Ding M, Wang J
Translational oncology 2026 Jun;68:102788

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Effects and mechanisms of ginsenoside Rg1 in alleviating hypothalamic oxidative stress and metabolic dysfunction via Nrf2-Tyrosine metabolism axis.

Huang Z, Zheng Y, Fan Z, Wei Z, Cai J
Molecular and cellular endocrinology 2026 Jun;616:112775

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Dual-targeted manganese-doped carbon dots activate the cGAS-STING pathway and immunogenic cell death for potent glioblastoma immunotherapy.

Li Z, Yu C, Che H, Xu D, Lu D, Wang Y, Li X, Ma S, Zhang X, Zhang Z, Yu R
Materials today. Bio 2026 Jun;38:103073

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A dual-responsive CO-releasing nanogel ameliorates retinal ischemia-reperfusion injury by restoring mitochondrial homeostasis and attenuating cGAS-STING pathway activation.

Xiao D, Qin J, Zhang F, Tao T, Tang W, Cai X, Tao L, Wang X, Jiang Z
Materials today. Bio 2026 Jun;38:102974

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SRSF1 as a promising biomarker and key player in the pathogenesis of Alzheimer's disease.

Liu Y, Zhao Y, Yao Y, Liu D, Sun Y, Xu W, Yu H, Chi L
Molecular medicine reports 2026 Jun;33(6)

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Lung cancer cell-derived exosomal EHF drives M2 macrophage polarization via transcriptional activation of RNF41 to promote tumor progression.

Chen Z, Ying J, Huang G, Shang W, Shi K, Wang Z, Wang L, Ding D, Zhang C, Tan Y
Regenerative therapy 2026 Jun;32:101104

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Glaesserella parasuis serotype 5 disrupts the swine respiratory epithelial barrier via NBR1-mediated selective autophagic degradation of Claudin-1.

Wang Q, Song C, Song C, Fang K, Yuan Y, Wang J, Fan H
Veterinary microbiology 2026 Jun;317:111030

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Thrombospondin-1 triggers calreticulin expression in human mucoepidermoid carcinoma MC-3 cells via the PERK/CHOP pathway.

Bao S, Zhu Y, Guo L, Yang S
Oncology letters 2026 Jun;31(6):234

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HSP72 alleviates heat stress-induced oxidative damage in boar Sertoli cells through modulating the AGE-RAGE/NOX4/NF-κB axis.

Jiang Q, Yang J, Ma J, Gao N, Weng B, Ran M
Animal reproduction science 2026 Jun;289:108144

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ZDBF2/SIRT6-mediated H3K27 deacetylation inhibits ferroptosis and reduces sensitivity of oral squamous cell carcinoma to cisplatin.

Liu K, Rong L, Shuai Y, Mu R, Ding H, Chen B, Jin L
Pathology, research and practice 2026 Jun;282:156419

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Dietary serine supplementation improves growth performance and intestinal immunity and modulates gut microbiota in chronic oxidative stress-induced weaned piglets.

Chen H, Liu Y, Jin S, Wang C, He Y, Zhou H, Chen M, Feng Y, Wang W, Ma H, He X, Liu D, Li T, Yin Y, He L
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2026 Jun;25:122-133

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STAT3 inhibition ameliorates cognitive dysfunction in type 2 diabetes mellitus by modulating astrocytes via Nrf2 pathway activation.

Wang J, Chen P, Li Y, Wang R, Ding W, Yu R, Qin Q, Wu R, Wei W, Shi J, Yuan H, Zhuang C, Sun Y
Free radical biology & medicine 2026 Jun;249:165-179

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Semaglutide alleviates age-related dry eye disease by restoring lacrimal gland structure and function.

Zuo X, Zeng H, Wang Y, Chi K, He Y, Huang Z, Yu H
Free radical biology & medicine 2026 Jun;249:138-151

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Baimaside, a flavonoid glycoside from Apocynum venetum, ameliorates sepsis by allosterically inhibiting NF-κB p50-mediated IL-6 transcription.

Zhang Y, Li W, Liang Y, Zang L, Chen X, Xiong X, Zhang S, Li Y, Qu X, Geng J, Xin Y
Biochemical pharmacology 2026 Jun;248:117868

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Lipophagy fuels phosphatidylcholine synthesis for Newcastle disease virus replication.

Yang M, Chen J, Su X, Kan X, Tan L, Song C, Qiu X, Liao Y, Yu S, Ding C, Sun Y
Autophagy 2026 Jun;22(6):1351-1368

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Matrix stiffness promotes corneal fibrosis through the YAP/TAZ-β-catenin mechanotransduction pathway: Proteomic and functional validation.

Li K, Fu H, Miao L, Lu Y, He C, Liu Y, Hu Z, Xie B, Lv X, Lu F, Lin M, Hu L
Acta biomaterialia 2026 Jun;216:215-233

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Overexpression of Thioredoxin-1 alleviates morphine-induced neuroinflammation in BV-2 cells and the ventral tegmental area of mice.

Lu Z, Long Y, Li X, Zhang L, Bai J
Neurochemistry international 2026 Jun;196:106169

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TIMM23-ERAL1 Axis: A novel regulator of mitochondrial apoptosis in hepatocellular carcinoma.

Chen Y, Qian Q, Li J, Hu S, Wen Y, Tu L, Tan L, Chen W, Wang L, Fang Y, Jiang W, Xu Q, Huang D, Li X
Biochimica et biophysica acta. Molecular basis of disease 2026 Jun;1872(5):168235

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Microglial GLUL loss worsens TBI outcomes by amplifying the arginine-citrulline pathway.

Li J, Zhao Y, Yang Y, Dai Q, Tian R, Wang J, Ye J, Zhang L, Li L
Biochimica et biophysica acta. Molecular basis of disease 2026 Jun;1872(5):168230

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Hepatocyte specific Rab27a knockout aggravates metabolic dysfunction associated fatty liver disease.

Hu JY, Liao XY, Ran RZ, Lu TT, Lin Y, Wang MW, Lin MJ, Liang X, Yang MQ
Biochimica et biophysica acta. Molecular basis of disease 2026 Jun;1872(5):168223

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Clu(+) transitional alveolar epithelial cells promote lung injury repair and fibrosis progression.

Wang Y, Guo J, Wang Y, Liu Q, Cui Y, Ning Z, Chen Y, Liu Y, Luo Z, Gao H, Jin T, Wang X, Guo E, Zhang Y, Bian Y, Pan T, Wang S, Li X, Liang H, Gu Y
British journal of pharmacology 2026 Jun;183(12):3252-3271

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Single-cell transcriptomics reveals the ameliorative effect of gastrodin on cholestatic liver fibrosis.

Pan D, Zheng T, Chen C, Qiu J, Deng Z, Jiang Z, Chen Y, Xiao C, Xu Y, Fu L, Linghu K, Chen J, Fan F, Zhang Q, Tao L, Hu X, Zhao L, Shen X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158165

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Network pharmacology-guided self-assembling quercetin hydrogel from Astragalus membranaceous accelerates diabetic wound healing.

Liu M, Zhou H, Wang J, Wang Y, Cai C, Han C, Dong L, Wang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158137

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Xueshuantong injection alleviates ischemic heart failure via targeting PFKP-mediated endothelial-to-mesenchymal transition.

Su L, Mo R, Dai Y, Wang Z, Lai S, Mo L, Jiang T, Li X, Chen M, Li Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158085

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Platycodin D3 protects against sepsis-associated acute lung injury through direct inhibition of the PKM2-NLRP3 axis.

Wang J, Yao L, Cui K, Zhao J, Yang M
Cellular signalling 2026 Jun;142:112443

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Adhesion molecule with Ig-like domain 1 regulates stability of carotid plaque via TGFβ/Smad signaling pathway by interaction with TGFRII.

Hu X, Li X, Chen J, Li Y, Zhao Z, Yin X, Duan S, Wang B
Cellular signalling 2026 Jun;142:112412

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VDAC1-mediated cytosolic leakage of mtDNA triggers pyroptosis of nucleus pulposus cells by activating the TLR9 signaling pathway.

Hu T, Yan M, Chen Y, Chen S, Song Z, Jing X, Hu B, Liu H
Cellular signalling 2026 Jun;142:112387

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Enhanced AAV production via rational design of a novel pHelper vector integrated with HSV-1 helper genes.

Ren H, Nie J, Song Z, Mo W, Yang Y, Bai Z
Synthetic and systems biotechnology 2026 Jun;12:352-363

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Leveraging ANXA1 to enhance recombinant protein yields in CHO cells: A UPR-Mediated bioprocessing approach.

Zhao Q, Zhang HJ, Han MM, Abiti J, Dong YJ, Wang JN, Lu JT, Wang W, Zhang X, Geng SL, Qiu LL, Wang XY, Hua ZC, Wang TY, Jia YL
Synthetic and systems biotechnology 2026 Jun;12:197-208

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DAPK1 orchestrates cell division and junction to control corneal epithelial development.

Yang M, Zhao Z, Bu W, Li L, Lin X, Hu M, Dong D, Jiao L, Shan Y, Liu M, Li D
European journal of cell biology 2026 Jun;105(2):151532

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Farrerol ameliorates hepatic insulin resistance via AMPKα1/mTOR/SREBP-1 pathway: A study in T2DM rat models and palmitic acid-induced BRL 3 A hepatocytes.

Li Y, Feng X, Zheng L
Tissue & cell 2026 Jun;100:103367

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A natural product-hybridization approach toward anticancer drug discovery: synthesis and antitumor evaluation of CTBC6, designed from sulforaphane and magnolol.

Tao C, Chen M, Liu B, Chen H, Ji F, Huang J, Chen J, Guo Y, Liu X, Yuan H, Feng Y, Li Z, Cheng Y, Luo D, Wu D, Lin X, Xie J, Peng J, Chen Z
Bioorganic chemistry 2026 Jun 5;173:109697

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Synthesis and biological evaluation of novel naphthoquinone [2,3-d] thiazole derivatives as potent 17β-HSD10 inhibitor.

Liu E, Dao S, Cui C, He W, Zhang L, Tang H
Bioorganic chemistry 2026 Jun 5;173:109669

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Activating NK cell immunity against prostate cancer with Hedysarum polybotrys Hand.-Mazz.: A multi-omics integration of computational prediction and experimental validation on PI3K/AKT and PD-1/PD-L1 axes.

Zhan L, Liu Q, Zhang C, Pu J, Ren L
Journal of ethnopharmacology 2026 Jun 28;365:121564

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Bie-Jia-Jian Pill: Inhibiting tumor glycolysis and promoting CD8(+) cell-mediated anti-tumor immunity by targeting HIF-1α-PI3K/AKT/mTOR and CCL20 in hepatocellular carcinoma.

Liu Y, Yang X, Qin M, Chen W, Liu C, Jiang W, Wang Y, Tan S, Sun H, Chen J, Sun H, He S
Journal of ethnopharmacology 2026 Jun 28;365:121554

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Ailanthone ameliorates CCl(4)-induced liver fibrosis by targeting PKM2-mediated macrophage M1 polarization and glycolytic reprogramming.

Wan Y, Wang T, Wang K, Huo Q, Cheng X
International immunopharmacology 2026 Jun 15;179:116640

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EDIL3 regulates caveolin-1-dependent endothelial permeability in subchondral bone during osteoarthritis.

Ma Y, Feng K, Tian K, He X, Yan J, Wang R, Ma P, Tang Z, Zhu G, Yang Y, Sun R, Su Y, Xue D, Chen Z, Lin X, Jin Q
International immunopharmacology 2026 Jun 15;179:116637

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TRIM27 promotes microglial M2 polarization and neuroprotection via TBK1-dependent autophagy in cerebral ischemia-reperfusion injury.

Xie D, Hu S, Long P, Huang J, Li X, Yuan Y, Liu H, Chen Y
International immunopharmacology 2026 Jun 15;179:116597

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Identifying the active components and mechanisms of Toona sinensis pericarps for the treatment of diabetic kidney disease using network pharmacology and experimental verification.

Zhang Y, Li H, Sun W, Wang R, Li Z, Chen Y, Lan S, Wang Y, Liu W, Li W
Journal of ethnopharmacology 2026 Jun 12;364:121531

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Ethnopharmacological relevance and anti-inflammatory mechanisms of Lycopi Herba in diabetic nephropathy: Integrated chemical profiling and pharmacological evaluation.

Chen LZ, Yang S, Ren DM, Wang XL, Shen T, Wang XN
Journal of ethnopharmacology 2026 Jun 12;364:121505

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Sijunzi decoction alleviates cancer cachexia myatrophy by suppressing M2 polarization of tumor-associated macrophages via the MCT1/lactate/H3K18 lactylation pathway.

Nie D, Zhang Y, Jia R, Fang Z, Zhu G, Xu B, Guo T, Zhang H
Journal of ethnopharmacology 2026 Jun 12;364:121500

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Exploring the molecular mechanism of Shenling baizhu formula in the treatment of ulcerative colitis via the cGMP-PKG signaling pathway.

Chen J, Chen Y, Zheng H, Ding T, Xiang Y, Zhou X, Wang W, Li J, Li Z, Peng C, Fu Q, Li T, Fu Y
Journal of ethnopharmacology 2026 Jun 12;364:121498

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Multi-omics analysis reveals Yishen Qutong formula promotes ferroptosis in Lewis lung cancer associated with Keap1/Nrf2/Nqo1 pathway modulation.

Li S, Cui Y, Zheng S, Yan Y, Jin Y, Chen Y, Yu J, Li Y, Feng L
Journal of ethnopharmacology 2026 Jun 12;364:121469

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IGHG1(+) malignant epithelial Cell-myCAF crosstalk via MIF-CD74/APP-CD74 drives early brain metastasis in NSCLC: Delineated via primary tumor-brain metastasis single-cell and spatial transcriptomics.

Yang L, Yang H, Zhao M, Wen Y, Wu L, Chen Q, Cao F, Zhao Y, Ye D, Yuan M, Yu J, Sun X, Xing L
Cancer letters 2026 Jun 1;647:218451

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EP300/NCOA1 complex drives glioma angiogenesis via H3K27 acetylation-dependent activation of VEGFA.

Yang S, Yao X, Lin X, Yang D, Ying X
Experimental cell research 2026 Jun 1;459(1):115004

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The neuroprotective effect of guanabenz combined with α-lipoic acid in the hSOD1-G93A amyotrophic lateral sclerosis model.

Zhang W, Zhang D, Han L, Wang D, Huo D, Tan X, Su X, Wang M, Xu J, Cheng J, Feng H
Brain research bulletin 2026 Jun 1;239:111890

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Zanthoxylum bungeanum essential oil alleviates DSS-induced ulcerative colitis in mice by modulating gut microbiota-dependent AhR/Nrf2 signaling.

Sun L, Xu B, Liang Y, Tao Y, Wei C, Du W, Chen P, Wang L, Yang X, Chen X
Food research international (Ottawa, Ont.) 2026 Jun 1;233(Pt 1):118986

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Numb attenuates LPS-induced neuroinflammation via autophagic regulation of Ifi204 in microglia.

Zhang S, Zang L, Li Y, Zhang Y, Chen X, Xin Y, He G, Zhou Z, Halalmeh I, Liang Y, Li W, Yang J, Geng J, Xiong X
Neurobiology of disease 2026 Jun 1;223:107386

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Discovery of frailty-linked proteins through multi-omics integration of brain and plasma proteomes with GWAS datasets.

Zhong J, Yuan M, Zhou E, Hu S
Experimental gerontology 2026 Jun 1;218:113120

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Effects of Lycium barbarum polysaccharide on the activation of pathogenic CD4 + T cells in a mouse model of multiple sclerosis.

Guo M, Deng G, Huang B, Lin Z, Yang X, Dong L, Wang Z, Guo Y, Yi M, Wang W, Jiang ML, Zhang CJ
Neural regeneration research 2026 Jun 1;21(6):2563-2572

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Salvianolic acid a inhibits neuroinflammation and ameliorates Alzheimer's disease pathology via the p38 MAPK/NF-κB pathway based on network pharmacology and experimental validation.

Xiao S, Han Y, Yan J, Wu L, Lin H, Yuan C, Song C, Ye J
International immunopharmacology 2026 Jun 1;178:116594

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Neutrophil aconitate decarboxylase 1/itaconate axis suppresses extracellular traps via alkylating GSDMD and alleviates murine liver injury.

Zhang K, Li T, Yang L, Li W, Liu W, Yang L, Chang N, Li L
International immunopharmacology 2026 Jun 1;178:116578

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SPI1 mediates CST2 transcription to promote the proliferation, metastasis, and angiogenesis of esophageal cancer.

Chen F, Yu L, Wang D, Zhao Y, Li C
Archives of biochemistry and biophysics 2026 Jul;781:110832

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A foam cell-targeted lipophagy restoration strategy stabilizes vulnerable atherosclerotic plaques.

Li H, Qin Y, Zhang J, Guo X, Hu X, Sun D, Zhao Y, Bernardini S, Xu D, Jiang P, Zhang H, Luo Y
Bioactive materials 2026 Jul;61:879-899

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4-Octyl itaconate attenuates radiation-induced intestinal injury associated with ferroptosis inhibition and microbiota rebalance.

Zhang S, Yue T, Jin P, Zhang X, Huo Q, Li W, Tian C, Dong H, Dong Y, Zhao Y, Li D
Free radical biology & medicine 2026 Jul;250:386-398

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Semaglutide ameliorates aortic endothelial cell dysfunction in sarcopenia through the SIRT1/cGAS-STING signaling axis.

Liu Y, Sun W, Huang Z, Qiao G, Tang L, Huang T, Wang X, Li L, Zhang X, Ye X, Yang P, Wu H
Free radical biology & medicine 2026 Jul;250:352-369

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GPX3 activates autophagy to protect cochlear spiral ganglion neurons from injury in age-related hearing loss.

An M, Yin H, Li Y, Cao H, Zhang Z, Yang J, Wang J, Liu T, Zhao L, Wang C, Miao R, Wang B
Free radical biology & medicine 2026 Jul;250:16-29

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Inhibition of endothelial ALOX12 mitigates cerebral ischemia-reperfusion injury by suppressing 12-HETE.

Wang T, Zhang J, Lu G, Han D, Mi T, Ma X, Wang L, He Z, Niu J
Free radical biology & medicine 2026 Jul;250:134-152

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Tolypaxillines A-J: indole diterpenoids with neuroprotective activities from a soil-derived fungus Tolypocladium album DWS131.

Tan YF, Chen XY, Wang C, Liang AL, Lu WY, Feng LM, Huang Q, Jiang YP, Liu S, Xia XB, Li J, Wang WX
Phytochemistry 2026 Jul;247:114855

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Curcumin inhibits colorectal cancer progression by regulating MDH2-mediated glycolysis and NAD(+) metabolism.

Zhao Y, Qin H, Sun W, Chen Y, Wang R, Li C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 Jul;213:116074

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HnRNP H1 binds to nucleocapsid protein and potential guanine-quadruplex site of viral RNA to promote PRRSV-2 proliferation.

Zhang L, Jing H, Song Y, Zhao P, Zhang Z, Duan E, Liu J, Li H
Research in veterinary science 2026 Jul;206:106188

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SSD: Targeting inflammasome and oxidative stress as a therapeutic strategy in inflammatory diseases.

Zhao Y, Fu X, Zuo H, Wang X, Li S, Wu T, Cheng C, Xu M, Xu G
Biochimica et biophysica acta. General subjects 2026 Jul;1870(7):130956

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Hesperetin alleviates high-fat diet-induced NAFLD by activating FXR to modulate ferroptosis homeostasis and suppress inflammation.

Chen S, Xie J, Yin G, Wang L, Jia Y, Zhang H, Ren Y, Ren L, He Q
The Journal of nutritional biochemistry 2026 Jul;153:110329

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circFAM53B-1 and circFAM53B-2 drive VSMC phenotypic modulation via ISG15-mediated suppression of SRF.

Zhao L, Li Y, Bi R, Shen J, Gao Y, Song J, Zhen Z, Zheng B, Lian H, Wen J, Zhang X
Cellular signalling 2026 Jul;143:112498

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Paeoniflorin suppresses the phenotypic transformation of vascular smooth muscle cells during atherosclerosis by regulating the MAPK/NF-κB pathways and ABCA1 expression.

Zhang Y, Sun L, Li F, Li Y, Zhou Q
Cellular signalling 2026 Jul;143:112477

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PIN1 suppresses bladder cancer progression by inducing cellular senescence and activating the interferon response pathway.

Zhang L, Chen C, Huang W, Dong L, Zhang J, Liu B, He W
Cellular signalling 2026 Jul;143:112476

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Mechanistic insights into Nicotine-derived nitrosamine ketone (NNK) in multiple sclerosis via integrated systems analyses.

Xiao X, Cui T, Hu S, Shen S, Huang Y, Cui C, Tan H, Qiu W, Zhao Y
Gene 2026 Jul 5;997:150158

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Chen's Jinshui Pills ameliorate diabetic retinopathy in mice and are associated with intestinal barrier protection and anti-inflammatory effects.

Jiang Y, Ding J, Zhou M, Yang X, Liang Y, Zhao X, Wang J, Liao Y
Journal of ethnopharmacology 2026 Jul 15;366:121661

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Regulatory role of MRTF-A in macrophage polarization and the therapeutic mechanism of Bushen Wenyang Huayu decoction in endometriosis.

Meng X, Qi J, Yang X, Zhang L, Fu X, Li J, Chen J
Journal of ethnopharmacology 2026 Jul 15;366:121602

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MCPIP1 modulates host antifungal immunity and exacerbates lethal Candida albicans infection.

Gao X, Tan L, Ding H, Yu R, Liu Y, Tan W, Han X, He Y, Lai X, Cao J
International immunopharmacology 2026 Jul 15;181:116715

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Design, synthesis, and biological evaluation of pyranone-carbamate hybrids as selective butyrylcholinesterase inhibitors with anti-neuroinflammatory activity for Alzheimer's disease.

Liu X, Xu J, Lin C, Gao X, Xie Y, Chen X, Huang Q, Ye R, Shi H, Zhang L, Ye ZC, Wu C, Zha D
Bioorganic chemistry 2026 Jul 15;176:109887

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Structure-based design of the approved drug zafirlukast identifies HLC40 as a potent WDR5 WIN-site inhibitor with antitumor efficacy.

He L, Shen C, Fan C, Li Y, Liu S, Song J, Zheng T, Huang X, Wen J, Xu J, Lan P, Min J, Sun P, Huang Y, Chen X
Bioorganic chemistry 2026 Jul 15;176:109869

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Targeting NBL1/PI3K/AKT axis to enhance the chemosensitivity and radiosensitivity of esophageal squamous cell carcinoma.

Wang B, Zeng R, Lei L, Yang Z, Feng B
International immunopharmacology 2026 Jul 1;180:116665

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Overexpression of mitofusin 2 ameliorates inflammation and oxidative stress in lipopolysaccharide-induced mastitis model by regulating phosphofurin acidic cluster sorting protein 2.

Zhou X, Zhang Y, Ma H, Fu S, Liu J, Guo W, Tian X, Huang B
Animal models and experimental medicine 2026 Jan;9(1):154-167

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Carbon dot superoxide dismutase nanozyme enhances reactive oxygen species scavenging in diabetic skin wound repair.

Yan Z, Zhang Y, Chen Q, Li J, Ning X, Bai F, Wang Y, Liu X, Liu Y, Zhang M, Liu C, Xia Y
Journal of advanced research 2026 Jan;79:691-706

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Metformin attenuates colitis via blocking STAT3 acetylation by reducing acetyl-CoA production.

Li X, Xiang Z, Wang X, He H, Xu M, Tan C, Wu X, Zhang J, Dong W
Journal of advanced research 2026 Jan;79:393-407

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Cytosolic acetyl-coenzyme A is a signalling metabolite to control mitophagy.

Zhang Y, Shen X, Shen Y, Wang C, Yu C, Han J, Cao S, Qian L, Ma M, Huang S, Wen W, Yin M, Lei QY
Nature 2026 Jan;649(8098):1022-1031

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Basement membrane-associated gene P3H2 regulates osteosarcoma progression and epithelial-mesenchymal transition through AKT/mTOR signaling axis.

Pan R, Zhang Y, Wang H, Guan J, Chen Z, Xiao L, Ru N, Zhao J, Cheng Y, Feng S, Zheng X
Translational oncology 2026 Jan;63:102569

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Inhibitory effects of berberine hydrochloride on porcine epidemic diarrhea virus in vitro and in vivo.

Cai M, Wei Z, Wu Z, Zhang Z, Xu W, Zhang G, Zheng Z, Gong L, Li M
Virology 2026 Jan;613:110711

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YKT6 Is Essential for Male Fertility by Promoting Meiosis Progression During Spermatogenesis of Mice.

Cen J, Yu X, Wang Z, Liu W, Xu J, Fang Q, Gao F, Cao Y, Liu H
Cell proliferation 2026 Jan;59(1):e70079

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Intermittent intra-articular delivery of FGF8b enhances cartilage homeostasis and attenuates osteoarthritis progression.

Peng X, Han J, Tian Y, Li X, Zhang X, Li S, Yang J, Chen L, Zhou S, Su N, Mao X, Zhang B, Chen H, Yang J, Jin M, Li C, Jiang W, Liu P, Xie Y, Kuang L, Chen L
Journal of orthopaedic translation 2026 Jan;56:101037

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The PTBP1-EZH2-DOCK2 axis promotes M1 microglial polarization and exacerbates neuronal apoptosis following spinal cord injury.

Sha C, Pan F, Liu X, Wang Z, Dai H, Huang K
Journal of orthopaedic translation 2026 Jan;56:101016

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Early Intervention of Subchondral Bone Resorption Mitigates Cartilage Degeneration in TMJOA.

Cao MN, Feng SY, Gao CC, Xiao Y, Li YX, Lei J, Fu KY
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2026 Jan;55(1):133-146

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Mn(3)O(4)-potentiated bifunctional hydrogel for mild temperature-controlled tumor ablation and osteogenesis.

Zhao Y, Wang W, Liu M, Cai Y, Wang Y, Dong Y, Bai YK, Zhu J, Tay FR, Niu L
Bioactive materials 2026 Jan;55:391-409

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COX17 Attenuates Diabetes-Associated Retinal Injury by Improving Mitochondrial Function.

Lian HY, Deng ZD, Yan M, Huang Z, Ye Y, Song YP
Clinical and experimental pharmacology & physiology 2026 Jan;53(1):e70098

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TBPH promotes lung cancer proliferation via mTORC1 activation and altered lipid metabolism while inducing toxicological effects in pulmonary cells in vitro and in vivo.

Li Y, Niu J, Qi Q, Liu C, Zhu Z
Toxicology 2026 Jan;519:154307

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Gastrin releasing peptide receptor antagonism in the paraventricular nucleus exerts antihypertensive effects in 2K1C rats.

Wang XM, Liu JJ, Wang YP, Bai C, Issotina Zibrila A, Xia WJ, Yang RN, Kang YM, Yu XJ
Toxicology and applied pharmacology 2026 Jan;506:117620

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SLC7A5-ERBB2 axis drives olaparib resistance via de novo lipid synthesis in ovarian cancer.

Liu S, He Y, Ning X, Xu W, Hu X, Qin L, Yang Y, Chen X, Ma R
Oncogene 2026 Jan;45(2):140-263

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Astrocyte-Derived CXCL10 Induces Neuronal Tau Hyperphosphorylation and Cognitive Impairments in Sepsis.

Guo C, Ruan H, Li W, Liu Y, Mahaman ARY, Guo Q, Zhou Y, Liu R, Wang J, Zhou C, Wang X, Li S
Neuroscience bulletin 2026 Jan;42(1):36-54

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Oroxin A suppresses non-small cell lung cancer via the HSP90AA1/AKT signaling pathway.

Wang M, Zhang Y, Liu R, Lin J, Wang T, Dong H, Yang J, Li X, Yu D
Naunyn-Schmiedeberg's archives of pharmacology 2026 Jan;399(2):2291-2305

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FBXO45 enhances cell viability and glycolysis in cervical cancer via DUSP2 ubiquitination-mediated ERK1/2 activation.

Xiang H, Sun J, Kong L, Wang Y, Qiu X, Li G, He J, Zeng J
Naunyn-Schmiedeberg's archives of pharmacology 2026 Jan;399(1):507-519

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Neuroprotective effects of SRS11-92 against oxidative stress-induced senescence via Nrf2/HO-1/NF-κB in Alzheimer's disease models.

Guo Y, Cao H, Zuo C, Huang Y, Gu Z, Song Y, Chen X, Jiang Q, Wang F
Inflammopharmacology 2026 Jan;34(1):495-507

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Calpeptin promotes osteogenesis through the Dlx3-RUNX2 pathway: in vitro and in vivo evidence for a dual-action osteoporosis therapy.

Liu P, Zhang Z, Lin X, Chen Y, Sun T, Guo W
Journal of drug targeting 2026 Jan;34(1):138-149

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Immunomodulatory mesoporous bioactive glass/interleukin-4 nanocomplex promotes bone regeneration.

Wang N, Chen Y, Cai Y, Liao L, Wang J, Wei J
International journal of biological macromolecules 2026 Jan;339(Pt 1):149869

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λ-Carrageenan regulates antiviral responses by targeting classical NF-κB and IRF3-mediated signaling pathways.

Sun X, Yao W, Hu J, Zhang Y, Liu R, Hu W, Li Y, Wan B, Kong Z, Zhang G
International journal of biological macromolecules 2026 Jan;338(Pt 2):149760

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Bacterial cellulose repairs asthmatic epithelial injury by reprogramming CDS1-mediated phosphatidylinositol metabolism to inhibit PI3K/AKT signaling.

Yu Q, Huang L, Wu Z, Zhuo J, Huang H, Cheng Y, Hu M, Wang Q, Liu D, Jiang X, Zhang J, Cai S, Dong H
International journal of biological macromolecules 2026 Jan;338(Pt 2):149695

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Yigu Decoction polysaccharides mediate gut microbiota and metabolites to promote bone formation-related protein expression and improve osteoporosis.

Zhang R, Yan K, Wu Z, Li G, Cheng F, Chen H, Zhang Y, Ge L, Chen Z, Chen T, Yao X
International journal of biological macromolecules 2026 Jan;336:149301

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A bioactive protein from Dioscorea polystachya residue alleviates hydrocortisone-induced erectile dysfunction in rats via TXNIP/NLRP3 pathway inhibition.

Yu S, Zhang Y, Xi J, Feng J, Xie T, Pan D, Zhao D, Ren J, Dong Z, Liu M, Wang S
International journal of biological macromolecules 2026 Jan;335(Pt 1):149351

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The USP1-WDR48 deubiquitinase complex functions as a molecular switch regulating tumor-associated macrophage activation and anti-tumor response.

Han D, Wang L, Jiang S, Su P, Chen B, Zhao W, Chen T, Zhang N, Wang X, Liang Y, Li Y, Li C, Chen X, Luo D, Yang Q
Cell death and differentiation 2026 Jan;33(1):92-110

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NEDD4 regulates VEGF signaling and mTOR to promote angiogenesis and the cell cycle in steroid‑induced osteonecrosis of the femoral head.

Li J, Zhen D, Qin Y, Guo C
Molecular medicine reports 2026 Jan;33(1)

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PGC-1α Transcriptionally Regulated by ChREBP Mitigates Neuropathic Pain Through Promoting Microglial Fatty Acid Oxidation and Anti-Inflammatory Response.

Hu Z, Pang J, Liu X, Zhao Y, Lu Y, Chen H, Zeng H, Yu Y, Zhao Y, Gao L, Zhang X, Jin J, Wang K, Shi Y, Zhan H, Wu W
CNS neuroscience & therapeutics 2026 Jan;32(1):e70744

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Prefrontal TRPM8 Receptor Modulates Epileptic Seizures via PKA/CREB Signaling Pathway in Mice.

Huang JZ, Lu GF, Jiang YH, Guo Y, Lin ZY, Zhang Z, Geng F
CNS neuroscience & therapeutics 2026 Jan;32(1):e70709

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Cadherin 11 regulates presynaptic vesicle trafficking and neuronal activity in autism-related brain circuit.

Cao X, Jia J, Li Z, Guo S, Duan J, Ma J, Yuan XB, Pan YH
Molecular psychiatry 2026 Jan;31(1):192-208

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Detection and quantitation of ferritinophagy using HaloTag tracing.

Kempelingaiah SK, Straus AJ, Mavodza G, Senkal CE
The Journal of biological chemistry 2026 Jan;302(1):111016

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High FSTL1 expression promotes bladder cancer progression by enhancing tumor cell migration.

Zhang H, Zhang X, Du Y, Xiong W, Zhang X, Zhang B, Shang P
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2026 Jan;28(1):265-276

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Ecdysteroid-enriched fraction of Cyathula officinalis suppresses synovial proliferation and inflammation to ameliorate RA by inhibiting the AKT/PI3K/mTOR signaling pathway.

Huang YH, Qiu L, Peng Y, Cai R, Xiao QQ, Li MC, Xu LJ, Fu Q
Journal of Asian natural products research 2026 Jan;28(1):175-197

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Bushen Huoxue formula component β-Estradiol 3-acetate treats osteoarthritis through enhancing the TLR4 ubiquitination.

Liu X, Wang S, Kuang C, Deng Y, Yuan S, Zou J
The Journal of steroid biochemistry and molecular biology 2026 Jan;255:106862

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Downregulation of BST2 Rescues Cochlear Nerve Demyelination in Age-Related Hearing Loss via Enhancing Schwann Cell Migration.

Liu M, Li Q, Cao H, Yin H, Yang J, Liu T, Wang J, Zhao L, Wang B
Aging cell 2026 Jan;25(1):e70325

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Hyperuricemia exacerbates acetaminophen hepatotoxicity via JNK activation and mitophagy reduction.

Liu Y, Peng B, Li D, Chen J, Lai Y, You Y, Jiang Z, Zhou X, Wu C, Chen L, Kwan HY, Yu L, Zuo D, Zhao X
Biochemical pharmacology 2026 Jan;243(Pt 1):117487

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Reticulon 3 deficiency induces ferroptosis via chaperone-mediated autophagy in ischemia-reperfusion induced acute kidney injury.

Zhang Y, Huang H, Li N, Dong Y, Zhao M, Zhang S, She W, Liu J, Xiang R
Free radical biology & medicine 2026 Jan;242:9-20

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Ammonium tetrathiomolybdate ameliorates heat stroke-induced murine liver injury by activating the Nrf2/HO-1 signaling pathway and inhibiting oxidative stress.

Jiang GL, Long LZ, Zhang XY, Yao TT, Cheng XY, Yu P, Zou LJ, He YJ, Jiang M, Meng J
Free radical biology & medicine 2026 Jan;242:535-548

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Eugenol attenuates intervertebral disc degeneration by inhibiting nucleus pulposus cell ferroptosis via the Nrf2/GPX4 pathway.

Sun S, Lu X, Yang S, Liang H, Lyu G, Chen Y, Yu L, Gao Z, Wang J, Xiao P, Jin L, Huang C, Wang X
Free radical biology & medicine 2026 Jan;242:508-520

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Chloride Channel-3 promotes ferroptosis of traumatic brain injury via SGK1/GSK3β pathway.

Nie Z, Fu H, Lu C, Tan L, Zhou J, Niu J, Liang R, Fang L, Fu Y, Zheng L, Wang B
Free radical biology & medicine 2026 Jan;242:474-484

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Hesperadin sensitizes gastric cancer cells to cisplatin via NOX1-dependent oxidative stress.

Zhu W, Li Q, Ji Z, Wu D, Chen J, Zhao Y, Wu H
Biomedical reports 2026 Jan;24(1):3

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A vagus-dependent gut microbiota-metabolite axis drives chronic inflammatory pain and working-memory deficits in mice.

Yue CB, Luan WW, Qiu D, Ding X, Gu HW, Liu PM, Hashimoto K, Yang JJ, Wang XM
Brain research bulletin 2026 Jan;234:111702

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Cycloastragenol protected hippocampal CA1 neurons by regulating redox homeostasis and alleviated cognitive impairment following cerebral ischemia-reperfusion.

Gao S, Zhu S, Qu T, Zou J, Yin L, Wang X, Yin X, Tong L, Li W
Brain research bulletin 2026 Jan;234:111689

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Effects of repetitive transcranial magnetic stimulation on apoptosis and MAPK/PI3K-AKT signaling pathways in rats with spinal cord injury.

Xu Q, Su J, Lei Q, Liu J, Wang J, Yang M, Song J, Chen H, Lu J
Brain research bulletin 2026 Jan;234:111687

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Cytotoxic Chaetoglobosins From a Soil-derived Chaetomium sp.

Xu J, Yang Y, Li Q, Dong Z, Guo Y, Jiang Z
Chemistry & biodiversity 2026 Jan;23(1):e02262

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A Discovery in Compatibility of Traditional Chinese Medicine: Spatholobus suberectus Dunn Suppresses Tripterygium wilfordii Hook. f.-Induced Main Toxicity and Enhances Its Main Efficacy.

Ji L, Zhang Y, Li Y, Song L, Wu X, Gong MZ, Zhang T, Du C, He Q, Wang Y, Wang J
Chemistry & biodiversity 2026 Jan;23(1):e01256

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Pharmacological characterization and neuroprotective efficacy of ZHB103, a novel long-acting rhKLK1.

Xu D, Jiang C, Ge C, Zhang T, Wang J, Wang H, Zhuang Y, Xu Z, Ding N, Ma BY
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Jan;23(1):e00830

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Ascorbic acid enhances antidepressant-like efficacy of esketamine: Hippocampal TARP-γ8-containing AMPA receptors mediate synaptic modulation.

Ke Z, Zhang Y, Jiang X, Luo J, Chen H, Ma Y, Chen Q, Zhao L, Cai B
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Jan;23(1):e00786

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SS-31 improves post-cardiac arrest brain injury by inhibiting microglial ferroptosis and polarization.

Jiang T, Zhang H, Sun Y, Ji X, Xue L, Pan C, Guo Y, Xu F
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Jan;23(1):e00772

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Exploring the Active Substances and Mechanism of Physalis Calyx seu Fructus Against Inflammation-related Respiratory Diseases via Integrating Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry, Network Pharmacological Analysis, and Experimental Verification.

Meng H, Xu LT, Li PP, Guo DX, Li GH, Gu HR, Wang XN, Lin YQ, Xu ZP, Shen T
Chemistry & biodiversity 2026 Jan;23(1):e00496

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Stiripentol-loaded self-nanoemulsifying delivery system for glioblastoma: therapeutic efficacy in 3D spheroid and xenograft model.

Yadav A, Patel H, Bhutkar S, Khairnar R, Kumar S, Patel K, Dukhande V
Nanomedicine (London, England) 2026 Jan;21(1):39-54

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Zinc Deficiency Aggravates High-Fat Diet-Induced Renal Injury by Regulating Oxidative Stress and Inflammation via the Nrf2/HO-1 Pathway.

Guan Y, Wu L, Wu M, Zhu Y, Luo P, Luo M
Biological trace element research 2026 Jan;204(1):60-73

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Increased glucose transporter 1 contributes to epithelial barrier dysfunction in allergic rhinitis.

Xia C, Zhu K, Yu C, Chen J, Gao T, Zhang Y
The World Allergy Organization journal 2026 Jan;19(1):101158

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The Role of Lactiplantibacillus plantarum CGMCC9513 in Alleviating Colitis by Synergistic Enhancement of the Intestinal Barrier Through Modulating Gut Microbiota and Activating the Aryl Hydrocarbon Receptor.

Lu H, Zhang G, Wang K, Liu K, Gao Y, Chen J, Li Y, Yan J
Probiotics and antimicrobial proteins 2026 Jan;18(1):623-635

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Potential Probiotic Lacticaseibacillus rhamnosus NKU FL1-11 Prevents Aging-Related Oxidative Stress and Inflammation via mTOR and FoxO Signaling Pathways in Zebrafish.

Li D, Gao X, Liu W, Jiang Y, Lu Y, Zhang Y, Lv H, Wang S
Probiotics and antimicrobial proteins 2026 Jan;18(1):1234-1252

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METTL1-mediated m7G methylation of FoxO1 regulates lipid metabolism in metabolic dysfunction-associated fatty liver disease.

Du J, Li Y, Zhu X, Gao J, Zhang Y, Wang C, Han D, Qiao L, Kou B, Guo R, Zhang H, Lin J
Metabolism: clinical and experimental 2026 Jan;174:156420

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Mitochondrial phosphopantetheinylation is required for oxidative metabolism.

Norden PR, Wedan RJ, Preston SEJ, Canfield M, Graber N, Longenecker JZ, Pentecost OA, McLaughlin E, Hart ML, Nowinski SM
Metabolism: clinical and experimental 2026 Jan;174:156413

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Sepsis-induced lipid droplet accumulation enhances antibacterial innate immunity through mechanisms dependent on DGAT-1 and interferon-beta.

Pereira-Dutra FS, Santos JC, Souza EK, Savi RV, Souza TS, Gil H, Espinheira-Silva H, Ferraro-Moreira F, Iack G, Cunha-Fernandes T, Igreja-Silva T, Palhinha L, Campos MM, Souza EFT, Cordeiro AF, Andrade-Dos-Santos P, Oliveira DM, Cardoso VS, Rajão MA, Teixeira L, Souza-Moreira L, Costa MFS, Reis PA, Bozza PT
Metabolism: clinical and experimental 2026 Jan;174:156389

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Lamtor5 interacts with LMBV PCNA to promote viral replication through autophagy.

Jiang Y, Tam K, Liu L, Liu Z, Huo X, Li H, Li W
Fish & shellfish immunology 2026 Jan;168:110947

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pH-Activatable engineered nanoparticle-based selective hexokinase 2 degrader provokes GSDME-dependent pyroptosis for cancer therapy.

Gong L, Li S, Sun J, Liu K, Wang S, Ji M, Hou P, Yan L, Yang D, Liu D
Acta pharmaceutica Sinica. B 2026 Jan;16(1):539-554

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Unveiling the active component of HuoXueTongFu formula: Emodin attenuates postoperative intra-abdominal adhesion by inhibiting HIF-1α-mediated glycolytic reprogramming.

Chen Y, Miao J, Yang L, Fang Y, Lian Y, Li G, Kong Z, Zhang L, Zeng L, Bian Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157719

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Berberine inhibits protein citrullination of fibroblast-like synoviocytes by suppressing autophagy via STAT3/PAD4 pathway.

Song YN, Zhang F, He Y, Li YH, Hu FY, Gao Y, Zong SY, Wang Y, Gao XY, Tang Q, Jiang XM, Tong FZ, Yan LP, Wei F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157706

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Unraveling the neuroprotective mechanism of gastrodin against CRS-induced depression in adult male mice via Notch3: Integration of proteomics, transcriptomics, molecular docking, and cellular validation.

Xiang H, Tan C, Long M, Zhang J, Zou X, Cai G, Li J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157705

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Notopterol attenuates synovitis via α7nAChR-dependent metabolic reprogramming of macrophage polarisation.

Chen X, Zhang C, Ye Y, Zhuang Y, Huang M, Yu H, Qin Z, Chen Y, Hong Z, Tu H, Wang Y, Wang Z, Wang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157684

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Safranal accelerates diabetic wound healing by suppressing ferroptosis through modulation of transcription factor Forkhead Box O3.

Wang Z, Zhu Y, Chen L, Hu Z, Cheng B, Lin Z, Li K
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157675

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Xinfeng Capsule ameliorates RA joint injury by inhibiting cuproptosis via the METTL3/miR-221/222-3p/ATP7A Axis.

Wang H, Wang A, Liu J, Zhu NF, Cao Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157644

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Yujie recipe attenuates bleomycin-induced pulmonary fibrosis via suppressing NF-κB/NLRP3 signaling in a Nrf2-dependent manner.

Qin L, Zhao B, Xiong Y, Chen L, Qi S, Ma Y, Zeng H, Song Y, Liu W, Tian T, Ge G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157607

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Piper longum ameliorates obesity by regulating gut microbiota and promoting adipose thermogenesis.

Cheng L, Liu Z, Gan M, Wang H, Si X, Zhang D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157588

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Synergistic Intervention of Piezo1 Activation and Fibrous Tissue Remodeling to Ease Side Effects of Intralesional Therapy for Keloids.

Jiang Z, Chen Z, Wu H, Ye K, Dong Z, Hu W, Su J, Chen Z, Chen X, Zhao S
Advanced healthcare materials 2026 Jan;15(4):e03332

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Assessment of the protective effects of milk osteopontin in necrotizing enterocolitis neonatal rat model.

Liu L, Li X, Lin C, Shi W, Lin H, Lönnerdal B, Yu G, Chen Z
The Journal of nutritional biochemistry 2026 Jan;147:110108

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Anti-Diabetic Effects of Ayanin, a Flavonoid Compound, in STZ/HFD-Induced Diabetic Mice by Upregulating GLUT4 and Suppressing Macrophage-Driven Inflammation in Adipose Tissues.

Lv Y, Wu C, Yang W, Wang C, Huang J, Wang J, Xia X, Wu D, Yang K, Guo Z, Liao S
Food science & nutrition 2026 Jan;14(1):e71429

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Polystyrene nanoparticles induced adverse pregnancy outcomes via the activation of placental ferroptosis and gut microbiota dysfunction.

He Z, Cai J, Liu R, Yan W, Yang G, Yu R, Xin L, Wan Z
Reproductive toxicology (Elmsford, N.Y.) 2026 Jan;139:109113

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A pH-Responsive Biomimetic Antioxidant Nanoplatform with Dual Renal Targeting for Synergistic Therapy of Acute Kidney Injury.

Zhang S, Xie Y, Zhang L, Qi Y, Liao Q, Xu C, Yang S, Zhou H, Tan Q, Qi S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(5):e15664

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NUSAP1 Recruits DAXX to Suppress HIF-Driven Triple-Negative Breast Cancer Progression.

Du Y, Wang J, Wang M, Zhang Y, Zheng M, Li H, Wang X, Sun H, Tang K, Shan C, Zhao Q, Meng X, Wang Y, Zhou J, Chen Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(5):e13380

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Lactobacillus Salivarius-Derived Indole-3-Acetic Acid Promotes AHR-PARP1 Axis-Mediated DNA Repair to Mitigate Intestinal Aging.

Cao Z, Zhang C, Lei H, Lin W, Yu W, Gao X, He Y, Li X, Xiang Q, Zhang Z, Luo W, Patterson AD, Zhang L, Chen G
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(4):e15794

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Molecular Insights into Fungal Glycosylphosphatidylinositol Transamidase Complex.

Hua Z, Ding X, Wu Y, Zhang D, Hu X, Yang P, Li J, Tan Y, Liu J, Zhang M, Zhang M, Liu X, Yu H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(2):e11340

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Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression.

Shi J, Li Z, Sun X, Yang Y, Luo Y, Song Z, Dong H, Jin L, Xie J, Shan Y, Zhao G
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(2):e05778

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NEAT1 Promotes Epileptogenesis in Tuberous Sclerosis Complex.

Kuang S, Liu T, Wei Z, Xu J, Han J, Wang J, Zhai F, Tian Y, Liang S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(1):e04316

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Calhm6 Governs Macrophage Polarization Through Chp1-Camk4-Creb1 Axis and Ectosomal Delivery in Inflammatory Responses.

Xin Y, Xiong X, Zhang Y, Zhang S, Zhang S, Yang Y, Liang Y, Zang L, Chen X, Li W, Halalmeh I, Zhou R, Li Z, Liu H, Geng J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(1):e02395

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Spatial transcriptomics uncovers lipid metabolic dysregulation driving immune-stroma crosstalk in Sjögren's Disease.

Li S, Liu Y, Zhang H, Xu S, Wen X, Tang Y, Zhang N, Fox DA, Chen Y, Pan Y, Lu C
EBioMedicine 2026 Jan;123:106074

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The oncogenic role of U2AF2/HKDC1 cascade in colorectal cancer by promoting cancer cell glycolysis and malignant phenotypes.

Feng W, Wu M, Zou H, Chen Y
Mutation research 2026 Jan-Jun;832:111929

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Shikonin improves intestinal barrier function through modulation of GPX4 expression in intestinal epithelial cells.

Yang F, Liang P, Guo H, Yan W, Wang G, Tang X, Liang Z
International journal of immunopathology and pharmacology 2026 Jan-Dec;40:3946320261427239

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Silencing RPL9 promotes malignant proliferation in breast cancer cells.

Zhu T, Dai J, Li W, Zhang H, Song Y, Zhang D, Liu R, Wang X, Shi Z, Tang H, Zhu X, Liu Y
International journal of immunopathology and pharmacology 2026 Jan-Dec;40:3946320261422055

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Extracellular vesicles secreted by adipose-derived stem cells alleviate dedifferentiation and senescence in monolayer-expanded chondrocytes by suppressing interleukin-1β-induced MAPK signaling.

Wu SC, Chang LH, Wu CW, Chen CH, Chang JK, Ho ML
Cell transplantation 2026 Jan-Dec;35:9636897261440426

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Eleutheroside E Attenuates Doxorubicin-Induced Cardiotoxicity by Suppressing Ferroptosis Through Activation of the Nrf2/SLC7A11/GPX4 Signaling Pathway.

Sun P, Chen L, Chen X, Zhang X, Guan J, Mo H, Liang Y, Li J, Yan J, Chen D, Zhong C, Yang P
Journal of cardiovascular pharmacology and therapeutics 2026 Jan-Dec;31:10742484261428559

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Copper chelator ammonium tetrathiomolybdate ameliorates the visceral hypersensitivity in dextran sulfate sodium-induced colitis mice.

Gao L, Wang R, Zhou J, Xu S, Feng S, Zhao L, Jiang C, Wang X
Molecular pain 2026 Jan-Dec;22:17448069261428972

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Spinal overexpression of CAPN1 in CaMKII neurons mediates paclitaxel-induced neuropathic pain via NCS-1-TRPV4 signaling.

Zhang YN, Chen SX, Li QY, You JQ, Zhou YH, Zang Y
Molecular pain 2026 Jan-Dec;22:17448069251413873

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Comprehensive Analysis of FOXO1 as a Tumour Suppressor Biomarker Related to Immune Infiltration and Cell Proliferation of Hepatocellular Carcinoma.

Xia S, Qin X, Pan C, Fan D, Yang D
IET systems biology 2026 Jan-Dec;20(1):e70051

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A proteomics-based study on the mechanisms of Terminalia chebula Retz processed Aconitum kusnezoffii Reichb against rheumatoid arthritis and its cardiotoxicity reduction.

Wang JH, Liu YL, Zhang CC, Song L, Mei L, Sa RN, Gao Y, Tu Y
Chinese medicine 2026 Jan 9;21(1):21

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Periodontitis pathogen Porphyromonas gingivalis promotes chronic obstructive pulmonary disease via affecting neutrophils chemotaxis and function.

Zhang L, Tian H, Ma Y, Xu J, Guo C, Wang Z, Ma J
International journal of oral science 2026 Jan 9;18(1):4

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ANGPTL8 links refeeding to monocyte dynamics and metabolic inflammation via the CCL5-CCR5 axis.

Kan RR, Wang SY, Meng XY, Huang L, Xiang YX, Mao BB, Zou HJ, Guo YM, Pan LM, Luo PQ, Yang Y, Liu ZL, Ma DL, Li WJ, Chen Y, Li DP, Yu XF
JCI insight 2026 Jan 9;11(1)

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Eleutheroside E alleviates cisplatin-induced ototoxicity by down-regulating MAPK/NF-κB/NLRP3 signaling pathway and inhibiting cochlear cell pyroptosis.

Zhang Y, Lu L, Tong B, Wang J, Liu K, Zhang J, Zhang D, Tian M, Sun W, Liu H, Wang P, Duan M, Tang Y
Communications biology 2026 Jan 8;9(1):214

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Integrated Bioinformatics and Experimental Validation Reveal Fuzheng Yi'ai Formula Induces Immunogenic Cell Death Via the PERK-eIF2α-ATF4 Pathway for Prostate Cancer Treatment.

Yu X, Peng L, Sheng W, Yang R, He Q
Biological procedures online 2026 Jan 8;28(1):9

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Ubiquitin-specific protease 19 promotes M2 macrophage polarization and ovarian cancer progression via NLRP3 suppression.

Zhang J, Pang Y
Discover oncology 2026 Jan 8;17(1):243

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NAT10-mediated ac4C modifications regulate glioblastoma progression.

Lin L, Xiong Y, Guo Y, Tu Z, Luo P, Fang Z, Zhang L, Huang K, Wu L
Cell death & disease 2026 Jan 8;17(1):181

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BDH1 Mediates Aerobic Exercise-Induced Improvement in Skeletal Muscle Metabolic Remodeling in Type 2 Diabetes Mellitus.

Wu M, Ma X, Dai W, Li K, Gao H, Guo Y, Xiao W
Biomolecules 2026 Jan 8;16(1)

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Hypoxia promotes progression of cervical cancer by modulating the ATXN3-enhanced P53 stability or STAT5 phosphorylation.

Zhang R, Chai S, Zhang F, Lai J, Wang R, Xu G, Fan X, Li B, Cai C
Cell death discovery 2026 Jan 8;12(1):4

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Asiatic Acid Attenuates Salmonella typhimurium-Induced Neuroinflammation and Neuronal Damage by Inhibiting the TLR2/Notch and NF-κB Pathway in Microglia.

Zou W, Li J
International journal of molecular sciences 2026 Jan 7;27(2)

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Rho-related GTP-binding protein RhoE (RND3) regulates multiple myeloma bone disease.

Gao Q, Tang W, Mi Z, He S, Yang H, Wang F, Huang J, Zhang Y, Wen J, Li L, Luo H, Liu X, Zhai X, Zhao X, Zhang L, Niu T, Zheng Y
Cancer cell international 2026 Jan 7;26(1):69

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Targeted stress granule regulation by engineering a non-catalytic O-GlcNAc transferase.

Wang N, Hou F, Ma S, Liu S, Wei H, Fang W, Zhang K, Ge Y
Nature communications 2026 Jan 7;17(1):163

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Sivelestat sodium mitigates lung injury post-acute pulmonary embolism by inhibiting NE-SPP1 neutrophil recruitment and restoring redox balance.

Chen J, Xu P, Feng W, Xu H, Xu J, Zhou J
Scientific reports 2026 Jan 7;16(1):4832

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FTO-Eci1 Axis Mediates Exercise-Induced Cardioprotection in Pressure Overload Mice.

Wang J, Chang Z, Lin S, Sha G, Zeng W, Huang Q, Deng Q, Wang S, Hu M, Xia J
Biomolecules 2026 Jan 7;16(1)

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STT3A-mediated FCN3 N-glycosylation promotes Treg cell activation to drive hepatocellular carcinoma progression via Wnt/β-catenin.

Zhang H, Zhang P, Gong T, Zhang C, Wang Z, Zhao Y
Cellular oncology (Dordrecht, Netherlands) 2026 Jan 6;49(1):16

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METTL3-m6A-SLC25A11 Axis Promotes Chronic Hypoxia-Induced Cardiomyocyte Ferroptosis.

Li Y, Xia J, Wei Y, He M, He G, Zhu Y
Journal of the American Heart Association 2026 Jan 6;15(1):e041690

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2,8-Dihydroxyadenine disrupts epithelial integrity and alters kidney cell phenotype in vitro.

Helgudottir HR, Palsson R, Edvardsson VO, Gudjonsson T
Journal of molecular medicine (Berlin, Germany) 2026 Jan 6;104(1):23

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Allele-specific knockdown by an engineered DNAzyme capable of RNase H1 evasion.

Lee EM, Nguyen K, Setterholm NA, Malik TN, Chaput JC
Nucleic acids research 2026 Jan 5;54(1)

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USP5 inhibition stimulates immunogenic ferroptosis that enhances immunotherapy in diffuse large B-cell lymphoma.

Wu J, Liu C, Chen Q, Deng Y, Wang J, Gao Y, Wei B
Cell communication and signaling : CCS 2026 Jan 5;24(1):93

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miR-376c-3p mediates icariin's anti-osteoclastogenic effect by targeting Mmp3.

Yan H, Li J, Xie D, Zou Y, Zuo J, Xu Y, Ma D
Journal of orthopaedic surgery and research 2026 Jan 4;21(1):80

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Fuzheng Jiedu formula attenuates acute pneumonia by coordinated regulation of macrophage NLRP3 inflammasome and neutrophil NETs.

Liu K, Yan J, Chi F, Wang W, Zhang M, Hou Y, Bai G
Chinese medicine 2026 Jan 4;21(1):1

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Chronic Stress Leads to Time-Dependent Bone Loss Through HPA Axis Dysregulation and GR Nuclear Translocation Disorder.

Yan Y, Li J, Lu Z, Zhang Z, Hao G, Zhao Y, Liu H, Liu Y, Bao X, Duan M, Li Y
International journal of molecular sciences 2026 Jan 31;27(3)

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Hybrid bioinspired nanovescicles target tumor endothelial cells and regulate immuno-microenvironment for triple-negative breast cancer therapy.

Gui Z, Zhao L, Liu S, Zhang L
Journal of translational medicine 2026 Jan 31;24(1)

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ZM-306416 prevents ovariectomy-induced bone loss by promoting osteoblastogenesis and inhibiting osteoclastogenesis.

Li Y, Shi S, Yang D, Zhao L, Chen T, Xu K, Liang W, Chen J, Chang J
Journal of orthopaedic surgery and research 2026 Jan 31;21(1)

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Association of METTL14 expression with prognosis and immunotherapy in breast cancer.

Hu J, Wang Z, Lu Y, Wei Z, Dong L, Li Y, Yan H, Tang N
Translational cancer research 2026 Jan 31;15(1):45

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Multi-omics analysis links FERMT1 expression to patient survival, immunotherapy response, and metastasis across cancers.

Chen P, Xiao L, Lv C, Zhang Q, Wu Y, Chen M
Translational cancer research 2026 Jan 31;15(1):21

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Anti-inflammatory effect of high-abundance Core oligopeptides from white tea via the PI3K/AKT/NF-κB signaling pathway.

Lao Z, Lin X, Ye X, Ke W, Wu C, You X, Wang X, Zhao F
Food chemistry 2026 Jan 30;500:147412

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Mechanistic study on Kai Xin San's regulation of DARPP-32 phosphorylation in anti-depressant effects based on multi-omics.

Shan M, Xu L, Dong J, Zhang X, Fang X, Luo H
Journal of ethnopharmacology 2026 Jan 30;355(Pt B):120746

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Honghua Xiaoyao tablets ameliorate premenstrual syndrome by modulating HPA axis and restoring ovarian estrogen synthesis to attenuate hippocampal neuroinflammation.

Chen K, Gao S, Cai B, Ma Z, Liu X, Chen W, Lin N, Zhang Y
Journal of ethnopharmacology 2026 Jan 30;355(Pt B):120688

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Network pharmacology and molecular docking reveal the multi-target mechanisms of Paeoniae Radix Rubra in functional angiogenesis: Synergistic regulation of ADAM10-NOTCH and VEGFR2-PI3K/AKT signaling.

Zhang R, Hu R, Wang Y, Jiang H, Aheniyazi A, Tao J, Li J, Yang Y
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120532

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Poria cocos Attenuates LPS/D-Galactosamine-Induced Acute Liver Failure in Rats: An Integrative Exploratory Study Combining Network Pharmacology and In Vivo Validation.

Wen P, Jian X, Ren X, Zhao S, Yang Y, Ge H, Li L, Wang H, Li M, Wang L
International journal of molecular sciences 2026 Jan 30;27(3)

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Peroxiredoxin 1 mediates bleomycin-induced acute lung injury in mice via macrophage NOD1/NF-κB axis.

Jiang G, Zhang Y, Long L, Zhang X, Yao T, Cheng X, Yu P, Zou L, He Y, Jiang M, Liu Q, Meng J
Respiratory research 2026 Jan 30;27(1)

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Tenascin C(+) myofibroblasts exacerbate vascular neointimal hyperplasia by propagation of nerve-macrophage interactions in mice.

Tong X, Shi G, Fang Z, Tang S, Zhou B, Meng Q, Zhang P, Li H, Cai X, Wang Z, Zheng X, Chen W, Jiang G, Wang H, Jiang D, Li Q
Nature communications 2026 Jan 30;17(1)

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An injectable dihydroartemisinin nanocomposite hydrogel for dual-targeting PANoptosis and inflammation to treat osteoarthritis.

Li Q, Chen L, Sun Y, Wang C, Sun Y, Lu K, Li L, Sun H, Liu M
Journal of nanobiotechnology 2026 Jan 29;24(1)

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NLRP3-Mediated Neuroinflammation Participates in Resilience to PSD in C57BL/6 Mice.

Fu H, Xiong M, Xu Q, Liu X, Chen X, Su Y, Wu Z
Biomedicines 2026 Jan 29;14(2)

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Solasonine inhibits NSCLC malignant progression by regulating SLC7A11 ubiquitination degradation and inducing ferroptosis.

Wang Y, Li X, Zhou C, Qian M, Zou Z, Yang W, Wilfred NSJ, Huang G, Xu X, Xue F, Jin M
Respiratory research 2026 Jan 28;27(1):90

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Cryo-EM structure revealed a novel F-actin binding motif in a Legionella pneumophila lysine fatty acyltransferase.

Zeng WW, Komaniecki G, Liu J, Lin H, Mao Y
eLife 2026 Jan 28;14

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Cry2 deficiency leads to cognitive impairment through the microbiota-gut-brain axis mediated S1P/NLRP3/IL-1β pathway in mice.

Geng F, Zhao N, Zhou L, Liu XT, Chen X, Wang ZT, Zhang ZJ, Ren QG
Journal of neuroinflammation 2026 Jan 26;23(1):71

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GJB2 c.109G > A mutation activating IFI27-mediated mitochondrial apoptosis pathway leading to hereditary non-syndromic hearing loss.

Chen Y, Zhao P, Lin Q, Zeng Y, Qiu X, Huang T, Tang J, Xu L
Scientific reports 2026 Jan 26;16(1):6240

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LOXL2 and SYVN1 cooperate across cellular compartments to drive liver hepatocellular carcinoma progression.

Yan R, Jiang X, Shi R, Liu Z, Zhou W, Su L, Wang Z, Hu W, He Q, Zhong J, Yang Z, Bai H, Zhang S, Zhang S
Biochemical and biophysical research communications 2026 Jan 25;797:153201

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Vascular Non-Inflammatory Molecule-1 Aggravates Acute Kidney Injury Induced Acute Lung Injury Via Promoting Neutrophil Extracellular Traps Formation.

Liu C, Yang Y, Song Y, Wu W, He P, Han Y, Gu W, Hu Y
Inflammation 2026 Jan 23;49(1):60

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Circulating adipocyte fatty acid-binding protein exacerbates LPS-induced neurotoxicity by crossing the disrupted blood-brain barrier and promoting neuronal apoptosis.

Ibrahim MM, Li C, Qiu L, Hu Y, Xu A, Yang S, Chang J, Fang C
Cell communication and signaling : CCS 2026 Jan 23;24(1):119

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BTLA-mediated regulation of neuroimmune responses enhances recovery after intracerebral hemorrhage.

Wu Y, Zhang Y, Fu P, Huang M, Chen S, Li Y, Wu T, Rastegar-Kashkooli Y, Cheng N, Zhao T, Wang Y, Wang X, Wang J, Wang J, Jiang C
Journal of neuroinflammation 2026 Jan 23;23(1):69

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NLRC5 Regulates Enterovirus 71 Infection Through an IFN-β-Dependent Pathway.

Fang W, Zhu B, Ge T, Liu X, Li B, Lu B
Viruses 2026 Jan 23;18(2)

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Integrated Phosphoproteomics Identifies TGFβ-Dependent Phosphorylation Events Linking Kinase Signaling to Autophagy in Palatogenesis.

Peng X, Chen J, Zheng X, Zhao X, Wang Y, Wang X, Du J
Proteomes 2026 Jan 23;14(1)

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Aebp1 loss in osteoprogenitors leads to skeletal defects resembling Ehlers-Danlos Syndrome by diminishing Wnt/β-catenin signaling.

Feng S, Feng Z, Deng Z, Wei Y, Lian R, Jin Y, Zhao S, Jin Y, Zhang Z, Zhao L
JCI insight 2026 Jan 23;11(2)

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The critical role of GRP78/BiP MARylation in ER stress of KRAS-mutant colorectal cancer.

Zhang S, Chen X, Gong Q, Huang J, Tang Y, Xiao M, Li M, Li Q, Wang Y
JCI insight 2026 Jan 23;11(2)

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Hypoxic mesenchymal stem cell-Derived Exosomal circPTP4A2 improves granulosa cell mitochondrial function via YBX1.

Zhu X, Shi X, Lu J, Li W, Liu Y, Jiang L, Lv Y
Cellular and molecular life sciences : CMLS 2026 Jan 22;83(1):82

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Cleavage of host tRNAs by mycoplasma membrane-associated nuclease.

Akiyama Y, Takenaka Y, Kunii N, Aoyama K, Yamada A, Abe T, Tomioka Y, Ivanov P
Nucleic acids research 2026 Jan 22;54(3)

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METTL16-m(6)A-PGC-1α axis contributes to exercise-induced mitochondrial adaptations in skeletal muscle of high-fat diet-fed insulin-resistant mice.

Chen C, Jiang C, Xiang Q, Hu Y, Wu H, Huang C, Zhou H, Xu Y, Hou M, Liu W, Han X
BMC biology 2026 Jan 22;24(1):41

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Intestine-Specific Ferroportin Ablation Rescues from Systemic Iron Overload in Mice.

Castillo C, Gim S, Das NK
Nutrients 2026 Jan 22;18(2)

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The Taurine-Slc6a6 Axis Promotes Breast Cancer Progression by Alleviating Oxidative Stress and Accelerating Cell Cycle Progression.

Cai P, Liu X, Lin M, Xie S, Yuan L, Lin Z, Zhang Y, Cai S
Cells 2026 Jan 22;15(2)

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Rhodotorula mucilaginosa JAASSRY1 Ameliorates Cyclophosphamide-Induced Immunosuppression by Regulating Gut Microbiota and Activation of Spleen TLR4/MyD88/NF-κB Pathway.

Yang M, He Y, Miao X, Sun M, Niu H, Hua M, Li D, Xu H, Wang J
Journal of microbiology and biotechnology 2026 Jan 21;36:e2510031

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Neutrophil-derived exosomes inhibit gastric cancer progression via miR-101-3p-mediated suppression of MCL1.

Wang J, Zhang J, Qian Y, Wang Y, Wang S, Fan B, Shi J, Wang J, Meng S, Dong X, Fu M, Zhang X, Ji R, Fang X, Zhang X
Cancer cell international 2026 Jan 21;26(1):88

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Integrating bioinformatic analyses and experimental validation of disulfidptosis-related genes and TMX4 in melanoma progression.

Yi Y, Tao R, Shi Z, Chen L, Zhu Z, Wu M
Cancer cell international 2026 Jan 20;26(1):86

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CCL14, identified by multi-omics approach, serves as a novel indicator of disease severity and progression in lymphangioleiomyomatosis.

Bai W, Hua L, Wang X, Guo M, Chen L, Liu B, Wang Y, Zhou Y, Wang Q, Zhang N, Xie M
Orphanet journal of rare diseases 2026 Jan 20;21(1):59

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TA-Zr/Ce Nanozyme-Mediated Lipopolysaccharide Dephosphorylation: A Targeted Strategy for Sepsis Treatment with Hemoperfusion Applications.

Zhao X, Shao R, Yu Y, Hu Z, Jiang Y, Zhou Y, Zhong Z, Zhou J
ACS nano 2026 Jan 20;20(2):2523-2544

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The UFL1-AKT positive feedback loop promotes breast cancer progression by enhancing lipid synthesis.

Meng F, Du Y, Liang J, Li H, Wang J, Tang K, Kong R, Sun H, Yin T, Qin J, Yang X, Shan C, Liu M, Yang G, Zhang J, Wang Y, Zhou J, Chen Y
Nature communications 2026 Jan 20;17(1):614

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ALDH2/eIF3E Interaction Modulates Protein Translation Critical for Cardiomyocyte Ferroptosis in Acute Myocardial Ischemia Injury.

Chen X, Yu X, Zhong S, Sha P, Li R, Xu X, Liang N, Zhang L, Li L, Zhang J, Zhou M, Lv T, Ma H, Wang Y, Ye Y, Yin C, Chen S, Tian J, Sun A, Wang W, Yan D, Yang HT, Huang H, Li P, Yin H
Circulation 2026 Jan 20;153(3):164-184

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Glycolytic heterogeneity drives metabolic-targeted therapy in pancreatic ductal adenocarcinoma.

Chianese U, Papulino C, Saggese G, Ali A, Ciotola M, Lonardo E, Cortese M, Favale G, Di Mauro A, La Gioia D, Golino V, Sommella E, Campiglia P, Franco R, Ciardiello F, De Vita F, Carafa V, Altucci L, Benedetti R
Signal transduction and targeted therapy 2026 Jan 20;11(1):25

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Molecular mechanism of resistance to lonafarnib conferred by mutations in the cysteine-rich region of respiratory syncytial virus fusion glycoprotein and discovery of a lonafarnib-derived antiviral PROTAC.

Yang Q, Xue B, Qiu X, Yang K, Tang J, Zhou A, Zou J, Mao Y, Zhong J, Zhou Y, Zhang W, Zhang Q, Xiao Q, Tang W, Li Z, Ye W, Zou G, Peng W, Shang J, Xu X, Li Y, Chen X
Journal of virology 2026 Jan 20;100(1):e0148725

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MEN1 Promotes Ferroptosis by Disrupting CD44 Alternative Splicing to Suppress Lung Cancer.

Pan T, Zhu J, Wang X, Tang D, Wang Z, Yang Y, Teng Y, Tian Q, Dan G, Chen C, Yu D, Liu M, Wang H, Zhang T, Guo B, Chen T, Jin B
Cancer research 2026 Jan 2;86(1):146-166

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CD48 is a novel immune checkpoint on tumour-associated macrophages in hepatocellular carcinoma.

Shi G, Xiao Y, Li Z, Qiu Y, Zhou Y, Zhang J, Li W, He L, Xie F, Cao H, Yu D, Du H, Li G, Zhang W, Wang S, Lei X, Zhang K, Zhang Y, Gao Y, Wang Z, Li M
Gut 2026 Jan 2;

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E3 ubiquitin ligase trim36 targets ddx3x for degradation to reprogram macrophage polarization and ameliorate tubal factor infertility in rats.

Shao L, Wang N, Yan Y, Zhao C, Tan Y, Wu Q, Tan Q, Huang Y, Liu L
Cell biology and toxicology 2026 Jan 19;42(1):23

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Exploring the molecular function of LYPD3 from pan-cancer to lung cancer: based on bioinformatics and cellular experiments.

Shi YX, Yan JH, Dai PH
Mammalian genome : official journal of the International Mammalian Genome Society 2026 Jan 19;37(1):26

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Neuroprotective Effects of Desert Milk Exosomes in LPS-Induced Cognitive Decline: Role of Microglial M2 Polarization and AMPK Signaling.

Li Y, Lu W, Qian W, Liao X, Wang P, Wang Y, Jiao W, Wang M, Zhao J, Yang J, Gao H, Li H
Nutrients 2026 Jan 19;18(2)

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TRV130 inhibits colon cancer progression via suppressing the Hedgehog signaling pathway: in vitro and in vivo evidence.

Zhuang Y, Jiang C, Guo Y, Sun J
Hereditas 2026 Jan 19;163(1):26

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In vitro experiments and bioinformatic analyses implicate KAT2A in the occurrence and development of hepatocellular carcinoma.

Xu ZY, Tan JH, Li JX, Huang SW, Xu JE, Zhong GH, Zhai JW, Tan XY, Liu GH
Scientific reports 2026 Jan 19;16(1):5737

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3'-phosphoadenosine 5'-phosphosulfate synthetase 2 (PAPSS2) is a potential diagnostic and prognostic biomarker in colon adenocarcinoma.

Jin A, Yang F, Li H, Wang G, Wang S, Tong S, Gao J
Scientific reports 2026 Jan 18;16(1):5655

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Narciclasine Alleviates Endothelial Inflammation and Atherosclerosis Initiation by Inhibiting Histone Lactylation-Mediated NF-κB Activation.

Wang Z, Zhang Z, Xin R, Ma M, Sun Z, Li Z, Zhang C, Liu L, Wu Z, Zhang Y, Chen Y
Inflammation 2026 Jan 16;49(1):49

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NAT10 drives hepatocellular carcinoma progression through SQLE-mediated cholesterol biosynthesis and is targetable by remodelin.

Wang Y, Yang X, Dong Y, Yang X, Hou Y, Fu Q, Yan J, Du Y, Zhang Q, Zhou Y, Wu A, Chang S, Xu J, Zhang C, Hu X, Meng H, Sun W, Liu D
iScience 2026 Jan 16;29(1):114488

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Vibration tailored to jawbone density with near-infrared light expedites orthodontic tooth movement.

Peng J, Wang X, Song W, Wang Y, Ye L, Qiao L, Chen G, Chen L
iScience 2026 Jan 16;29(1):114237

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Genetically engineered macrophages delivering TRAIL targeting the Wnt/β-catenin pathway to induce cytotoxicity against TNBC.

Huang M, Yu X, Jiang Z, Li X, Yang S, Luo S, Song C
Cell communication and signaling : CCS 2026 Jan 16;24(1):30

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Thonningianin A derived from Penthorum chinense Pursh alleviates cerebral ischemia/reperfusion-mediated apoptosis and pyroptosis through the activation of PINK1/Parkin-dependent mitophagy.

Yao Q, Hu G, Yin C, Wu A, Hu G, Qin D, Zhou X, Law BY, Du X, Chen L, Li J, Lin H, Long X, Wu J, Yu L
Chinese medicine 2026 Jan 16;21(1):40

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SNX-3 confers lysosomal fusion-competence to sustain basal autophagy.

Kang Q, Liu Z, Xiang L, Yang S, Yi P, Zhang R
Cellular and molecular life sciences : CMLS 2026 Jan 15;83(1):85

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HOXB4 Promotes Bladder Cancer Progression in Part Through Transcriptional Activation of Smoothened.

Jin Z, Yang W, Peng Y, Ma L, Li Z, Dong J, Ji Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Jan 15;40(1):e71388

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Discovery of XRF-1021, a 2,4-disubstituted-5-fluoropyrimidine derivative as a homeodomain-interacting protein kinase 2 inhibitor for the treatment of chronic kidney disease.

Hu X, Wang S, Fu S, Zeng J, Wu Y, Gong L, Cao Y, Zhang Y, Han Y, Ouyang H, Xiong Y, He X, Cheng J, Zou S, Chen Z, Tao L, Meng J, Huang L, Yuan Q, Peng Z, Li Q
European journal of medicinal chemistry 2026 Jan 15;302(Pt 2):118353

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BCAR3 Hypomethylation as a Potential Diagnostic Marker for Thyroid Cancer and Its Mechanism via Promoting EMT and AKT/mTOR Pathway.

Yu W, Mao Y, Yin Y, Yang J, Zhang Y, Huang X, Zhang Y, Jiang C, Yang R
Cancers 2026 Jan 15;18(2)

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Fractional carbon dioxide laser-induced photothermal activation of mesenchymal stem cell-derived exosomes accelerates diabetic wound healing by enhancing angiogenesis.

Chen JY, Ji Z, Guo K, Wang HN, Zhu CC, Li T, Zhao XB, Wang YT, Li Q, Jin PS, Li XY
World journal of diabetes 2026 Jan 15;17(1):112942

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Lipophagy modifies the catabolism of intracellular triglycerides by preferentially targeting small-sized lipid droplets in bovine mammary epithelial cells.

Kang F, Yang J, Fan Y, Yang Y, Han YQ, Dai H, Han L
Journal of the science of food and agriculture 2026 Jan 15;106(1):400-409

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Integrated microbiota and metabolomic analysis demonstrates the growth-promoting effects of Lactobacillus plantarum in Nile tilapia (Oreochromis nilotica).

Li L, Wang Y, Li Y, Wang T, Wang Z, Zhou N, Qiao F, Du ZY, Zhang ML
Animal microbiome 2026 Jan 14;8(1):14

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YTHDC1-Mediated m(6)A Modification of MAGI3 mRNA Regulates Proliferation and Differentiation of Myoblasts.

Chen Q, He S, Xue X, Zhang W, Li H, He X, Pu Y, Ma Y, Jiang L, Zhao Y, Zhao Q
Journal of agricultural and food chemistry 2026 Jan 14;74(1):1804-1818

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5-HT2C receptors in the glutamatergic neurons of dorsal raphe nucleus orchestrate the comorbidity of pain and anxiety in mice.

Zhang Q, Xie L, Zhu C, Yang S, Zhang X, Huang J, Wang Y, Ji Y, Wu Z, Huang C, Wang D, Yang L, Yang C, Hu S, Jiang R
BMC medicine 2026 Jan 13;24(1):84

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ORY-1001 Delays Retinal Photoreceptor Degeneration in rd10 Mice by Inhibiting H3K4me2 Demethylation.

Lu X, Peng GH
Biology 2026 Jan 13;15(2)

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Candidate Interaction Partners of Calpain-5 Suggest Clues to Its Involvement in Neovascular Inflammatory Vitreoretinopathy.

Gal J, Bondada V, Crasta R, Croall DE, Vary CP, Geddes JW
Cells 2026 Jan 13;15(2)

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Promoting the nuclear retention of HMGB1 attenuates astrocyte senescence.

Zhang N, Yang F, Shi J, Tang X, Fan A, Li W, Zhang F, Chai S, Chen Q, Wang C, Xu Y, Gong F, Lu Y, Zheng F
Journal of neuroinflammation 2026 Jan 12;23(1):55

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IL-25-ILC2-IL-13 axis improves traumatic brain injury by mediating CXCL-10-dependent regulation of blood brain barrier integrity.

Peng M, Shu D, Chen Z, Yang Z, Zhang M, Wang Q, Shao X
Journal of neuroinflammation 2026 Jan 12;23(1):53

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The effects of LINC00324 on cell proliferation, migration, and invasion via autophagy in melanoma.

Ma S, Liu C, Ding Y, Li M, Wang M, Feng S
Scientific reports 2026 Jan 12;16(1):2310

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Combination of GLP-1 receptor agonist and Akkermansia muciniphila Akk11 reduces adiposity and ameliorates MASLD in T2D mice.

Gao K, Yin Z, Zhang C, Dong Z, Wang R, Chen Q, Liu X, Jiang C, Wang Y, Guo B, Zhou Z, Jia Z, Sun H, Feng Y
Cell & bioscience 2026 Jan 12;16(1):18

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Nimbolide ameliorates ARDS and ulcerative colitis by disrupting NLRP3 inflammasome activation.

Xu H, Lin Y, Luo W, Sheng S, Xu Y, Zhang Z
Communications biology 2026 Jan 11;9(1):246

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Shen-Shuai-II-Recipe inhibits aerobic glycolysis through SIRT1 in 5/6 ablation/infarction renal failure model.

Lan T, Zhang X, Lyu X, Wu M, Wang C, Yang L
Scientific reports 2026 Jan 11;16(1):5022

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Jiao-tai-wan and its bioactive constituent jatrorrhizine exert antidepressant effects via the STING pathway.

Gao Y, Wang H, Ma P, Nie K, Gong M, Su H, Huang W, Dong H, Tang Y
Journal of ethnopharmacology 2026 Jan 10;354:120547

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Fici hirtae radix alleviates influenza A virus-induced acute lung injury via TLR4-PI3K-AKT/p38 MAPK-NF-κB signaling pathway.

Liang WT, Li JJ, Lv ZR, Chen ZH, Yang YD, Xie TY, Ruan YJ, Tu XP, Zeng FF, Wei Shi, Yang X, Zhang FX
Journal of ethnopharmacology 2026 Jan 10;354:120522

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Potential components and action mechanism of Tongzhi Surunjiang Pills against acute gouty arthritis: UPLC-MS/MS, network pharmacology, molecular docking, and transcriptomic analysis.

Fu W, Ye A, Yang H, Hou X, Wang Z, Hu Z, Yu X, Li X, Yu Z, Li Y, Qiu Y, Mei Z, Xu L
Journal of ethnopharmacology 2026 Jan 10;354:120516

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Guiqi Yishen granule alleviates obstructive nephropathy-induced renal fibrosis by targeting PI3K/AKT signaling pathway.

Zhu J, Cao S, Wang T, Wang N, Yang L, Tang X, Jiang M, Zhu Q, Yu H, Wu D, Peng WX
Journal of ethnopharmacology 2026 Jan 10;354:120490

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Maidong Dishao Decoction can inhibit the activation of the cGAS-STING signaling pathway of Sjögren's syndrome by reducing oxidative stress in salivary gland epithelial cells.

Zhu W, Chen L, Li Y, Gu R, Zhang Y, Lu Y, Wang Y
Journal of ethnopharmacology 2026 Jan 10;354:120470

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Investigating the Protective Mechanisms of Ginseng-Natto Composite Fermentation Products in Alzheimer's Disease: A Gut Microbiota and Metabolomic Approach.

Li Z, Wang H, Yuan H, Zhang Y, Yang B, Ji G, Yao Z, Kuang M, Wu X, Wang S, Wang H
Pharmaceuticals (Basel, Switzerland) 2026 Jan 10;19(1)

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The role of GPD2 on ferroptosis in sepsis-induced acute lung injury.

Han Y, Dai C, Hu D, Yao Y, Peng W, Zheng Y, Zeng Q, Xie H, Huang J
Biochemical and biophysical research communications 2026 Jan 1;794:153066

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LGR5/mTORC2 axis regulates cellular metabolic plasticity to maintain tumorigenesis in hepatocellular carcinoma.

Lv G, Zong Q, Wang L, Lv H, Wu Z, Liu C, Wang S, Cao D, Wang H, Yang W
Cancer letters 2026 Jan 1;636:217978

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HPGDS promotes tubular injury and interstitial inflammation in diabetic nephropathy by activating canonical pyroptosis pathway.

Huang Y, Li S, Li W, Zhang T, Lu Z, Li C, Zhu X, Yang T, Lu Q, Dong B, Wang J, Zhou W, Yan M
International immunopharmacology 2026 Jan 1;168(Pt 2):115911

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C498-0670 ameliorates severe acute pancreatitis through dual modulation of NF-κB and STAT3 signaling pathways.

Luo H, Xu J, Lei K, Zhang W, Zhang Y, Guo S, Li X
International immunopharmacology 2026 Jan 1;168(Pt 2):115842

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Trillin attenuates liver ischemia-reperfusion injury by inhibiting autophagy through regulation of the cGAS-STING pathway.

Wu T, Yu Q, Wang Y, Tang H, Guo W
International immunopharmacology 2026 Jan 1;168(Pt 2):115790

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Construction and clinical validation of a machine-learning-based consensus prognostic signature (MLPS) for osteosarcoma via multi-cohort data integration.

Chen L, Wu H, Ren R, Zhang Y, Zhu Z, Chen X, Wang L, Gan X, Kang H, Pu H, Xiong W
International immunopharmacology 2026 Jan 1;168(Pt 1):115831

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Swietenine alleviated cardiomyocyte inflammation in diabetic cardiomyopathy by regulating NAMPT/SIRT1.

Huang Y, Zhang T, Lu Z, Li S, Wei R, Li W, Shan Y, Liu Y, Zhang C, Yang T, Yan M
International immunopharmacology 2026 Jan 1;168(Pt 1):115823

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Phosphoglycerate kinase 1 as a potential biomarker and therapeutic target for diabetic sarcopenia.

Li F, Wang Q, Li R, Gao Y, Wang Y, Chen Q
QJM : monthly journal of the Association of Physicians 2026 Jan 1;119(1):23-33

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Potential regulators and metabolic networks of muscle fatty infiltration: genomic and radiomics investigation based on 33 300 participants.

Tan J, Ding Z, Zheng J, Zhang J, Chen X, Li Z, Shi L, Chen J, Sun Y
International journal of surgery (London, England) 2026 Jan 1;112(1):472-485

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Targeting fatty acid metabolism in hepatic macrophages mitigates acetaminophen-induced liver injury and promotes regeneration in mice.

Jiang X, Wu B, Xie L, Li H, Chen C, Huang P, Chen X, Zhu Q, Wang H, Hu C
Hepatology communications 2026 Jan 1;10(1)

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tRF-1-31-Pro-AGG-1-M5 mediates STAT1 to regulate epithelial-mesenchymal transition in intrahepatic cholestasis of pregnancy.

Liu Y, Tahir MU, Zhang C, Feng F, Shao Y
Tissue & cell 2026 Feb;98:103206

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Antimycin A inhibits alpha-herpesvirus replication by disrupting the formation of pyrimidinosomes.

Guo YQ, Wang MH, Tang N, Zhao YB, Wo LJ, Liang DX, Huang R, Tang YD, Sun YJ, Yin X
Journal of advanced research 2026 Feb;80:1179-1196

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MARK4 as a novel biomarker of acute myocardial ischemia-induced sudden cardiac death.

Ye X, Hong G, Dou R, Wang Z, Lin Z, Shao Y, Yang J, Lin J, Shen Y
Legal medicine (Tokyo, Japan) 2026 Feb;80:102766

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SEC11A identified as a critical host factor for HMPV through virus-induced alternative splicing.

Huang Y, Guo J, Zheng S, Chen A, Yao L, Zhang K, Zheng L
Biosafety and health 2026 Feb;8(1):31-41

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Effect and Mechanism of Apoptotic Bodies from Inflammatory Periodontal Ligament Stem Cells on Macrophage M1 Polarisation.

Weng J, Zhang Z, Zeng L, Xia J, Xu Z, Zhu G, Zhang H, Wang J, Pathak JL, Yu L
International dental journal 2026 Feb;76(1):103981

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Identification of MDM4 as a Prognostic Biomarker and a Target for Therapeutics in Colorectal Cancer.

Shang X, Zheng X, Jiang A, Zhao N, Chen Y, Liu N, Chen M, Liang X, Ruan Z, Tian T, Fu X, Yao Y
Biotechnology and applied biochemistry 2026 Feb;73(1):28-42

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Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer.

Wang F, Xu X, Guan B, Li X, Yuan J, Guan W, Chen J, Fang J, Lu Q, Xu G
International journal of oncology 2026 Feb;68(2)

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High-Fat Diet Promotes Glycolysis in Hepatocellular Carcinoma by Suppressing Hepatic Kisspeptin Signaling in Mice.

Zhao R, Nie L, Shi Y, Jin L, Pan Y, Zhang X, Wang Z, He M, Zhang G, Yuan Q, Xia T, Wang S, Yang J, Yang W, Yuan D
Molecular carcinogenesis 2026 Feb;65(2):246-257

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MSI1 Accelerates Prostate Cancer Cell Proliferation, Migration and Glycolysis by Promoting ABHD2 Transcription.

Huang D, Zheng Q, Zhou L
Biochemical genetics 2026 Feb;64(1):1146-1160

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GATAD2B promotes ovarian cancer malignant progression via MYC/CD47 Axis.

Guo T, Nie D, Xu J, Zhou R, Ye Y, Zhu Y, Lin M
Translational oncology 2026 Feb;64:102540

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Immunomodulatory effects of bacterial lysates on the IL-17 signaling pathway in an asthma mouse model.

Gao M, Wang X, Yin L, Wei X, Li F
The Journal of asthma : official journal of the Association for the Care of Asthma 2026 Feb;63(2):159-168

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Porphyromonas gingivalis Outer Membrane Vesicles Promote Gingival Fibroblasts Senescence via IL21R-AS1.

Li Z, Xiao Y, Ma J, Chen X, Zhou Y, Gou H, Xu Y
Journal of periodontal research 2026 Feb;61(2):203-215

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Senotoxins target senescence via lipid binding specificity, ion imbalance and lipidome remodeling.

Moral-Sanz J, Fernández-Carrasco I, Ramponi V, Garrido A, Karbat I, Cabezas-Sainz P, Rivera-de-Torre E, Elsallabi O, Martín-Hernández R, López-Aceituno JL, Price NL, Sanchez L, Colmenarejo G, Martínez-Del-Pozo Á, Vetter I, Cogolludo A, Perez-Vizcaino F, Del-Pozo J, Reuveny E, Fernández-Rojo MA, Robbins PD, de Cabo R, Serrano M, Ikonomopoulou MP
Nature aging 2026 Feb;6(2):349-367

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Corin inhibits microglial inflammatory activation by suppressing mitochondrial dysfunction in intracerebral hemorrhage.

Yin R, Qiu C, Shen Q, Wang Z
BMB reports 2026 Feb;59(2):143-150

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Targeting NAD(+) Salvage Suppresses PBMC Inflammation to Improve Cognitive Function in Vascular Cognitive Impairment.

Li Z, Zhang HY, Feng R, Qi WX, Wang YT, Li Q, Zhang K
Stroke 2026 Feb;57(2):478-492

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Injectable microgels loaded with programmable WELNs based on mendelian randomization macroanalysis alleviate osteoarthritis by restoring the circadian rhythm.

Yan R, Li W, Zhao D, Zhao J, Ying S, Xiang L, Wang H, He T, Zhao C, Cui W, Zheng C, Yang L
Bioactive materials 2026 Feb;56:483-508

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CIAPIN1 as a Promoter of Oral Squamous Cell Carcinoma Progression.

Yang S, Sun C, Fang Z, Jin H, Li C, Zang H, Yang L, Li L, Saiyin W
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2026 Feb;55(2):209-218

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Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy.

Zheng R, Liu Y, Zhou S, Liu G, Liu X, Yang Y, Zhang Y
Oncology reports 2026 Feb;55(2)

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Gut microbiome and metabolome analysis reveal the alleviating effect of naringenin on duodenal damage in Ningdu yellow chickens caused by heat stress.

Lin S, Shi Y, Liu J, Luo J, Liao K, Liu P, Gao X
Avian pathology : journal of the W.V.P.A 2026 Feb;55(1):64-78

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Inhibition of Setd7 protects against cardiomyocyte hypertrophy via inhibiting lipid oxidation.

Su HB, Wang JH, Zhang YY, Xu J, Liu JY, Li YH, Xiao CX, Wang CY, Chang J, Liu XH
Acta pharmacologica Sinica 2026 Feb;47(2):344-356

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Therapeutic Potential of MgH(2) in Mitigating Cisplatin-Induced Hearing Loss.

Hu Y, Zhang Y, Li S, Yu Y, Wang J, Lou Z, Zhang B, Xing Y, Chen Z
Neuroscience bulletin 2026 Feb;42(2):369-385

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Fucoidan induces ferroptosis in colorectal cancer cells by regulating the SLC7A11/GPX4 signaling pathway and modulating metabolic pathways.

Yang C, Feng C, Zhang N, Feng J, Xie S, Li X, Liu Q
Naunyn-Schmiedeberg's archives of pharmacology 2026 Feb;399(3):3863-3877

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Targeted inflammatory microenvironment remodeling and NIR-II photothermal therapy for abdominal aortic aneurysm.

Liu Y, Qiu P, Hao H, Ding A, Wu Z, Lei J, Peng Z, Pu H, Zeng C, Guo H, Wu X, Lu H, Qin J, Wang R, Liu H, Ye K, Lu X
Materials today. Bio 2026 Feb;36:102770

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Kartogenin-loaded chitosan composite scaffold with cartilage-mimetic microstructure for layered osteochondral repair and cartilage phenotype maintenance.

Liu H, Qiao H, Li R, Yang W, Guo X, Wang Y, Mei N, Wang J, Chang F
Materials today. Bio 2026 Feb;36:102727

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A novel biomimetic nanozyme orchestrates ulcerative colitis resolution by targeting KEAP1-NRF2-ARE pathway: Redox balance restoration, colonic barrier repair, immune homeostasis regulation.

Gong P, Wang Y, Qiu JH, Li G, Chen KW, Li Z, Wang X, Wang L
Materials today. Bio 2026 Feb;36:102627

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Intestinal metabolite TMAO promotes CKD progression by stimulating macrophage M2 polarization through histone H4 lysine 12 lactylation.

Tang Y, Li Y, Yang X, Lu T, Wang X, Li Z, Liu J, Wang J
Cell death and differentiation 2026 Feb;33(2):314-326

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Ripk1 is critical for preserving effector regulatory T cells and the suppressive transcriptional program in regulatory T cells.

Plaza-Sirvent C, Sturm H, Nocke MK, Ghorbani F, Bessen C, Greweling-Pils MC, Floess S, Niemz J, Huysentruyt J, Tougaard P, Huehn J, Geffers R, Todt D, Vandenabeele P, Schmitz I
Cell death and differentiation 2026 Feb;33(2):284-297

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Melatonin induces autophagy in neuroblastoma by alleviating Pak2‑mediated endoplasmic reticulum stress.

Qiu QQ, Zhang N, Xu YY, Qin JW, Yu GF, Song XR
Molecular medicine reports 2026 Feb;33(2)

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SIX2-Mediated Microglial M2 Polarization and Exosomal miR-3470b Delivery Protect Dopaminergic Neurons in Parkinson's Disease.

Kan JS, Cao XY, Ye YX, Huang XX, Sun GJ, Gao J
CNS neuroscience & therapeutics 2026 Feb;32(2):e70756

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Antimony Exposure Promotes Periodontitis by Activating Ferroptosis Pathway.

Zhou Y, Yuan F, Zhang R, Wang J, Muhaisen BOM, Tang C
Oral diseases 2026 Feb;32(2):550-565

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Exploring the potential mechanisms of PFAS exposure on colorectal cancer via combined bioinformatics analyses and experiments.

Hao W, Chen X, Xin H, Wang Z, Wen T, Xu D, Ma H
Ecotoxicology and environmental safety 2026 Feb;311:119870

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Genome-wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer.

Wang X, Mi B, Lv J, Tang X, Huang J, Liu F, Xing Y, Wen X, Wang Y, Zhong Y
Oncology letters 2026 Feb;31(2):62

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HDAC6-mediated PFKL deacetylation enhances aerobic glycolysis and promotes VSMC proliferation.

Hu ZK, Ren ZY, Pang JX, Li H, Yang MN, Dong LH
The Journal of biological chemistry 2026 Feb;302(2):111075

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Thymoquinone Protects Against Cardiac Hypertrophy via PPAR-γ/PI3K/Akt Pathway.

Qiu RB, Wu ZM, Xu ZQ, Hu LJ, Zhao ST, Zeng RY, Qiu ZC, Zhou LF, Lai SQ, Wang WJ, Wan L
Journal of cellular and molecular medicine 2026 Feb;30(3):e70911

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Spinal cord Tau pathology induces tactile deficits and cognitive impairment in Alzheimer's disease via dysregulation of CCK neurons.

Zhou Y, Li WL, Liu ZQ, Ai WQ, Kou JX, Fan HW, Han ZT, Hu YZ, Zhang HH, Jia JJ, Zeng Y, Guo ZY, Man HY, Lu YM, Liu D, Zhu LQ
Nature neuroscience 2026 Feb;29(2):358-373

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Pharmacological activation of Wnt/β-catenin signaling is essential for oocyte developmental competence and enhances in vitro embryo production in water buffalo.

Ma X, Zheng H, Duan A, Xie Y, Zhou J, Shang J, Yang C
Animal reproduction science 2026 Feb;285:108070

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Targeting monocarboxylate transporter 1 with a copper-chelating coumarin-based bioconjugate: Synthesis and characterization.

Mari M, Belluti S, Pampanella L, Imbriano C, Zambon A, Storchi J, Pigani L, Tosato M, Rubagotti S, Capponi PC, Asti M, Patinec V, Tripier R, Ferrari E
Journal of inorganic biochemistry 2026 Feb;275:113130

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Efficacy and Mechanisms Underlying MRI-guided High-definition Transcranial Direct Current Stimulation Combined With Computerized Cognitive Remediation Therapy for Improving Cognitive Impairments in Schizophrenia: Study Protocol for a Randomized Controlled Trial.

Wei Y, He S, Luo P, Liu R, Su H, Shen Z, Feng S, Wu Y, Ji G, Zheng W, Wang F, Wang C
Alpha psychiatry 2026 Feb;27(1):46768

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Synergistic neuroprotective effects of the ROCK inhibitor Y27632 and atorvastatin in optineurin-E50K-mutant mice through inhibition of scleral fibroblast transdifferentiation.

Zhu X, Liu X, Xu X, Ding Z, Zhang S, Wang Q, Zhang D, Qiu L, Chen S, Du M, Yuan H, Song W
Experimental eye research 2026 Feb;263:110760

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CUL5 E3 ubiquitin ligase regulates the evasion of bladder cancer cells to CD8+ T cell-mediated killing by inhibiting autophagy.

Gao X, Yu Y, Sun J, Zhao H, You Y, Shi X, Wang K, Hong S, Xiong X, Huang C, Zhang H, Jiang G
PLoS biology 2026 Feb;24(2):e3003647

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The 3C-like serine protease activity of porcine astrovirus nsP1a/3 mediates mitochondrial apoptosis and MAVS cleavage to facilitate viral replication and antagonize type I interferon response.

Du Y, Lv Y, Feng X, Luo Y, Wei X, Shao S, Zhou Y, Ouyang K, Yin Y, Chen Y, Wei Z, Huang W, Qin Y
PLoS pathogens 2026 Feb;22(2):e1013987

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Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine.

Wu S, Zhao J, Azmi AA, Gupte A, Thibodeau J, Liu S, Yang J, Wang G, Edwards H, Polin LA, Kushner J, Dzinic SH, White K, Boerner J, Hüttemann M, Yang J, Wang Y, Taub JW, Ge Y
Molecular oncology 2026 Feb;20(2):555-572

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MD2 mediates COPD pathogenesis by inducing airway inflammation and ferroptosis through the TLR4/MyD88 pathway.

Xi X, Chen H, Ji H, Xiao T, Liu Z, Chen J, Ge X, Zhang Y, Zhu X
Biochimica et biophysica acta. Molecular basis of disease 2026 Feb;1872(2):168099

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Smart responsive injectable hydrogel loaded with icariin inhibits ferroptosis and promotes nucleus pulposus repair in intervertebral disc degeneration.

Lin Z, Mai L, Luo H, Wang Z, Lin Y, Wang H, Chen S, Su G, Hu X, Chen B, Cao X
Biomaterials advances 2026 Feb;179:214513

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β-Glucan Protects Against Sepsis-Induced Kupffer Cell Loss by Inhibiting Pyroptosis and Promoting Self-Renewal.

Adams J, Li T, Zhu P, Garbe C, Tu F, Casteel J, Yakubenko V, Williams DL, Li C, Wang X
Immunology 2026 Feb;177(2):286-298

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Apigenin alleviates DFZ-induced cardiac, renal, and intestinal injury in carp by modulating oxidative stress and inflammatory responses.

Guan T, Zhou W, Gao Y, Dong Q, Jin X, Li Y, Xu Z, Yu H, Dong J
Fish & shellfish immunology 2026 Feb;169:111054

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Intricate polycyclic dimeric phthalides derived from Angelica sinensis with potential to attenuate renal fibrosis.

Lv H, Cao B, Mu Y, Yi P, Zhang C, Liu Z, Huang X, Han L
Bioorganic chemistry 2026 Feb;169:109424

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L-tetrahydropalmatine attenuates methamphetamine-induced pulmonary vascular remodeling via CaSR-BMP2/mTOR signaling.

Chen L, Wang X, Zhu X, Hu WT, Yang D, Wang Y
Bioorganic chemistry 2026 Feb;169:109418

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Dimethyl bisphenolate inhibits glioblastoma growth by promoting cell cycle arrest and apoptosis.

Chen R, Hao M, Liu M, Xue P, Liu Y, Zhang H, Xu L, Li R, Zhang X, Wang Z, Chen R, An J, Cao Q, Song S, Zhong H, Qu G
Bioorganic chemistry 2026 Feb;169:109340

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Oral colon-targeted paeonol emulsion for ameliorating ulcerative colitis based on charge adsorption.

Zhang L, Xiong X, Lu W, Li J, Zhang R, Cai Z, Lv H, Zhang Z, Ju J, Yang Y
Drug delivery and translational research 2026 Feb;16(2):675-692

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Lipid Droplets-Targeted Thermally Activated Delayed Fluorescence Photosensitizer for Photodynamic Therapy-Mediated Ferroptosis: a New Strategy for Tumor Radiosensitization.

Xu S, Wang X, Pu K, Liu T, Pei J, Zhao X, Yu J, Liu J, Hu HY
Advanced healthcare materials 2026 Feb;15(7):e04496

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Microfluidics-Inspired Microgels with Intrinsic Bioactivity for Advanced Burn Wound Therapy.

Liu Z, Wu H, Wang X, Wu X, Wu H, An X, Chen J
Advanced healthcare materials 2026 Feb;15(6):e02477

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DUSP1 Attenuates Renal Injury in Diabetic Nephropathy by Modulating Ferroptosis: Evidence From Animal Experiments.

Liu J, Zhang J, Zou Y, Chen W, Xu J
Immunity, inflammation and disease 2026 Feb;14(2):e70340

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WTAP Contributes to Periodontitis Pathogenesis by Promoting PDLSC Senescence and Impairing Osteogenic Differentiation via m6A-Dependent Regulation of TP53BP1.

Xiong M, Wang T, Liu Y
Immunity, inflammation and disease 2026 Feb;14(2):e70335

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Reducing Neuroinflammation via Inhibition of Fibrinogen Deposition and Microglial Activation as an Underlying Mechanism of Paning I Decoction in Ameliorating Parkinson's Disease Symptoms.

Chen YJ, Chen JW, Xie MR, Wang RZ, Wan YL, Zeng J, Zhong BW, Zhou SQ, Liu F
Immunity, inflammation and disease 2026 Feb;14(2):e70310

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TWEAK exacerbates allergic conjunctivitis via PKM2-dependent NF-κB activation and macrophage M1 polarization.

Yang Y, Zhang Y, Fu J, Yin X
Cellular signalling 2026 Feb;138:112264

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Idebenone alleviates rotenone-induced mitochondrial dysfunction through mitophagy and mitochondrial biogenesis in muscle cells.

Zhang C, Li M, Meng L, Xia W, Wu G
Cellular signalling 2026 Feb;138:112221

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Heat shock response-driven signature and DNAJB11 in HCC: A multifaceted role in prognosis, immune microenvironment, ferroptosis and therapeutic sensitivity.

Geng W, Li T, Zhang J, Shen M, Zhang J, Li J, Ma X, Chen J, Sun H, Liu X, Cao P, Fan Y, Tan K
Journal of thermal biology 2026 Feb;136:104415

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VDLIN: A Deep Learning-Based Platform for Methylcobalamin-Inspired Immunomodulatory Compound Screening.

Guo X, Zhao Y, Rong X, Niu C, Hu S, Liu Q, You F
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(7):e13775

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Icaritin Ameliorates Cisplatin-Induced Mitochondrial Metabolic Dysfunction-Associated Nephrotoxicity and Synergistically Potentiates Its Antitumor Efficacy.

Luo P, Chen J, An Y, Meng K, Zhou W, Li W, Liu J, Zhao W, He W, Cao T, Huang J, Feng S, Yang S, Hu H, Liao J, He H, Hao M, Zhang Q, Wang J, Gao Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(7):e06712

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Discovery of a Novel DNMT1 Inhibitor with Improved Efficacy in Treating β-Thalassemia.

Shen Y, Wei J, Tang S, Wu D, Zong L, Ma S, Xiong Q, Gong R, Xu S, Peng C, Feng Q, Liu S, Liu Q, Ye Y, Zhao Q, Luo C, Huang P, Li Z, Kong X, Lan X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(11):e13469

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Bioorthogonal Sonodynamic Plug-and-Play Targeting Chimeras (SDPTAC) for Precise Targeted Protein Degradation.

Bao Y, Zhu Y, Wei X, Fang Y, Zhu J, Gao F, Dong G, He S, Sheng C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(10):e20975

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A Novel CYP2E1 Inhibitor, 4-Methyl-5-Acetylthiazole (Q11), Alleviates Obesity Via Modulating Adipose Inflammation and Mitochondrial Dysfunction.

Qiu J, Gao L, Wang L, Wang X, Jia L, Deng M, Tang L, Wen Q, Gao N, Xu H, Qiao H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(10):e15315

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Functional characterization of two protein C variants causing type I deficiency via cellular degradation or retention.

Yasuda I, Nagaya S, Yui R, Imai Y, Kuwajima Y, Morishita E
International journal of hematology 2026 Feb;123(2):156-165

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Lysine malonylation regulates human sperm motility.

Cheng Y, Tian Y, Chen H, Peng S, Chen Y, Peng Z, Luo T
Communications biology 2026 Feb 9;9(1):178

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Removing therapy-induced senescent cancer cells targets and potentiates the response of pancreatic cancer cells toward PARP inhibitors as maintenance therapy.

Li Y, Jia Z, Liu X, Xia X, Zhang L, Dai H, Li S, Zhou Y, Ma L, Bai Z
Apoptosis : an international journal on programmed cell death 2026 Feb 9;31(2):71

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LncRNA AC098613.1 promotes acute myeloid leukemia cell differentiation through CDC5L/ADAP1/NRD1 axis.

Jiang Q, Wang X, Yao H, Wang J, Tang P, Liang M, Pan Z, Li B, Lin C, Wu Q, Wang Q, Zheng Q, Kuok CF, Liu H, Sun C, Li D
Apoptosis : an international journal on programmed cell death 2026 Feb 9;31(2):67

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M2 polarization of macrophage induced by IL-33 promotes mouse sciatic nerve regeneration.

Xu D, Li Y, Zhang Q, Wu W, Du Y, Liu J, Shen J, Jin X, Li X, Guo J, Li L, Wen J
Cell & bioscience 2026 Feb 8;16(1)

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Onconase Induces Apoptosis in Dabrafenib-Resistant Melanoma Cell Lines Through Dysregulation of ROS Homeostasis, Antioxidant Protein Expression, and Mitochondrial Dynamics.

Passarini C, Cardile A, Zuanetti F, Zanrè V, Pacchiana R, Celesia A, Danzi F, Fiore A, Gotte G, Menegazzi M
International journal of molecular sciences 2026 Feb 7;27(4)

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Taurine Alleviates Sepsis-Induced Myocardial Injury by Inhibiting NF-κB Pathway-Mediated Inflammation, Mitochondrial Dysfunction, and Apoptosis.

Feng J, Ma T, Yang L, Li M, Xiao D, Gong P, Zhao A, Li P, Yao L
Cardiovascular toxicology 2026 Feb 7;26(2):27

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The GFPT2/O-GlcNAcylation/c-Myc axis promotes bladder cancer progression.

Xie H, Liao T, Tang H, Ban C, Cheng Z, Liao K, Li Y, Wei W, Zhou L, Yi X
Journal of translational medicine 2026 Feb 7;24(1)

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DNMT3A p.R882C driven proliferation and anti-apoptotic effects in pancreatic cancer cells.

Qu Z, Mao J, Qian Y, Cao J, Jiang S
Scientific reports 2026 Feb 7;16(1)

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TRIM26-mediated regulation of TRAF6 ubiquitination enhances host immune response during Toxoplasma gondii infection.

An X, Zhao X, Zeng T, Qiu H, Li L, Gao M, Gao S, Liu D, Zhou C, Han B, Zhou H
Cellular and molecular life sciences : CMLS 2026 Feb 6;83(1):102

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Comprehensive analysis of PANoptosis-related molecular subtypes and prognostic model development of clear cell renal cell carcinoma.

Zhou P, Xu Z, Gan W, Jin X
Discover oncology 2026 Feb 6;17(1)

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In situ coagulation environment regulation-assisted thrombus clearance via hydrogenated silicon-based nanothrombolytics.

Zhu YX, Chen Z, You Y, Chen Y, Yu W, Guan X, Zhu P, Yang J, Ge M, Chen X, Lin H, Shi J
Science advances 2026 Feb 6;12(6):eaea4782

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Multi-Omic and Spatial Profiling Identifies an Epithelial DKK1 Associated with Microenvironmental Remodeling in Pancreatic Ductal Adenocarcinoma.

Xu J, Qian K, Ding Y, Cheng J, Zhang X, Huang Y, Liu B
Current issues in molecular biology 2026 Feb 5;48(2)

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Discovery of α-carboline fused benzofuran-containing anticancer agents as rapid apoptosis inducers through intrinsic pathway.

Lin F, Luo Z, Wu Q, Lv L, Chen Z, He Y, Yuan HX, Zhao Y, Nie S
European journal of medicinal chemistry 2026 Feb 5;303:118464

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Cell-type resolved protein atlas of brain lysosomes identifies SLC45A1-associated disease as a lysosomal disorder.

Ghoochani A, Heiby JC, Rawat ES, Medoh UN, Di Fraia D, Dong W, Gastou M, Rastogi M, Hernandez V, Nyame K, Laqtom NN, Durso W, Valkova C, Isakova A, Kaether C, Wernig M, Gomez-Ospina N, Franke C, Ori A, Abu-Remaileh M
Cell 2026 Feb 5;189(3):765-782.e31

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Porphyromonas gingivalis-derived extracellular vesicles aggravate bone destruction in rheumatoid arthritis by promoting Syk-dependent osteoclastogenesis.

Guo J, Qiu Q, Yan X, Zhang Z, Zhang X, An N, Yin C, Yang D, Okamura H, Yoshida K, Sun H, Qiu L
International journal of oral science 2026 Feb 5;18(1):6

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Role of SERPINA1 in the tumor immune microenvironment of breast cancer and construction of a prognostic model.

Xia X, Liu J, Liu J, Chen S, Chen Z
Discover oncology 2026 Feb 5;17(1)

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From Kitchen Spice to Neuroprotector: The Role of 6-Shogaol in Parkinson's Disease Management.

Jin J, Li X, Wang Y, Yan Z, Lv A, Zhang Y, Zhuang P, Guo H
Journal of agricultural and food chemistry 2026 Feb 4;74(4):3558-3573

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Targeting macrophage glycogen metabolism attenuates ulcerative colitis by suppressing IL-1β production through UDPG-P2Y(14) signaling.

Tong S, Zhu T, Liang S, Cui Y, Ma Y, Zhang X, Bian Y, Wei K, Wu S, Ma J
Molecular medicine (Cambridge, Mass.) 2026 Feb 4;32(1):15

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Flos sophorae immaturus exosome-like nanovesicles alleviate ulcerative colitis by attenuating intestinal oxidative stress and inflammation through activating Aryl hydrocarbon receptor via gut microbiota and tryptophan metabolism regulation.

Wu H, Pang MM, Li YL, Huang JJ, Geng SZ, Hong JH, Liu PM, Yang JJ
Journal of nanobiotechnology 2026 Feb 4;24(1):132

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Caveolin-1 drives immunosuppression in esophageal squamous cell carcinoma by enhancing exosome secretion and macrophage M2 polarization via inhibition of MVB autophagic degradation.

Zhai KR, Zhao PL, Wang ZH, Feng HM, Li ZQ, Huang HR, Yang N, Su ZP, Cui BQ, Song TN, Li B
Journal of translational medicine 2026 Feb 4;24(1)

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Ginsenoside Rg5 inhibits colorectal cancer, at least partially by blocking the lysosomal degradation of colorectal cancer cells.

Guo X, Sun R, Su Y, Qin Q, Liu Y, Qiu C
Scientific reports 2026 Feb 4;16(1)

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C5aR1(+) microglia exacerbate neuroinflammation and cerebral edema in acute brain injury.

Zhou J, Ma S, Feng D, Tian Y, Li L, Guo H, Shi Y, Cui W, Dong J, Hao S, Guo C, Xu M, Han L, Bai H, He D, Cui X, Chen L, Wu X, Gao F, Hu Q, Zhang Z, Wang K, Zhou G, Feng T, Xue D, Lin Q, Wang L, Gao L, Heng L, Zhao T, Luo T, Tian B, Zhang X, Guo W, Li Z, Liu H, Ge S, Liu Q, Qu Y
Neuron 2026 Feb 4;114(3):444-462.e9

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Endosome maturation is orchestrated by inside-out proton signaling through a Na(+)/H(+) exchanger and pH-dependent Rab GTPase cycling.

Lee Y, Ouyang Q, Ma L, Fleishman M, Riaz HA, Schmidt M, Dupree JL, Mondal A, Mohanty P, Mittal J, Beckstein O, Lambright DG, Morrow EM
Research square 2026 Feb 4;

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Integrating Metabolomics and Network Pharmacology: Investigating the Therapeutic Mechanism of Atractylodes Rhizome Against Rheumatoid Arthritis.

Wen R, Xu C, Zheng H, Li C, Yu H
Pharmaceuticals (Basel, Switzerland) 2026 Feb 3;19(2)

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DMBX1 expression in colon cancer and its impact on prognosis and the tumor microenvironment.

Zhang K, Hu X, Chen J, Zhao Z, Yin X, Zhou L, Wang B
BMC medical genomics 2026 Feb 3;19(1)

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Puerarin Attenuates White Matter Injury and Blood-Brain Barrier Disruption After Intracerebral Hemorrhagic Stroke via cGAS-STING Axis.

Ouyang Y, Yu L, Shi Y, Chen Z, Tang X, Jin J, Huang Z, Tang X, Zhu B, Wang X
Biology 2026 Feb 3;15(3)

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RND3 restricts encephalomyocarditis virus replication by promoting IKKε ubiquitination and type I interferon production.

Ma P, Wang Z, Liu Z, Xie Q, Liu T, Li L
Microbiology spectrum 2026 Feb 3;14(2):e0174525

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MECP2 Insufficiency Attenuates RUNX2-Dependent Osteoblast Differentiation via miR-126-3p/DKK1-Mediated Canonical Wnt Signaling Inhibition in Rett Syndrome.

Dong S, Wang L, Kato H, Hirofuji S, Zhou Z, Ito Y, Hirofuji Y, Sato H, Kato TA, Sakai Y, Ohga S, Fukumoto S, Masuda K
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Feb 28;40(4):e71570

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KCTD15 Enhances Stem Cell-Like Properties and Promotes Triple-Negative Breast Cancer Progression Through KLF4/β-Catenin Signaling.

Yao L, Sun W, Xing J, Feng J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Feb 28;40(4):e71563

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Role of MED15 in Enhancing EMT and Metastasis in Bladder Cancer Through YAP1 Stabilization.

Liu ZX, Shi YY, Zhou DS, Chen SN, Liu XQ, Huang YT, Yang ZY, Liang YT, Huang MN, Yan Y, Qiao YK, Ma Y, Liu H, Qi L, Li M, Chan SH, Zhang XD
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Feb 28;40(4):e71558

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Anti-inflammatory effects and mechanisms of Podophyllum hexandrum rhizomes and fruits in a chronic pelvic inflammatory disease rat model.

Zhang B, Yang AT, Wang LN, Yu Q, Tan CC, Chao WH, Geng HY, Pei TX, Zhang L, Cao SJ, Qiu F, Kang N
Journal of ethnopharmacology 2026 Feb 28;357:120954

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Study on the mechanism of Sangbaipi Decoction in treating acute lung injury via the inflammasome NLRP3 signaling pathway.

Xu B, Wang Y, Xu Y, Zhang X, Wang X, Chen S, Li L, Bao H
Journal of ethnopharmacology 2026 Feb 28;357:120908

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Cardiospermum halicacabum Extract Attenuates UVB-Induced Photoaging in Human Skin Fibroblasts via Inhibition of the PI3K/Akt/mTOR Signaling Pathway.

Zhao K, Zhang C, Deng C, Zhu W
International journal of molecular sciences 2026 Feb 28;27(5)

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Integrated single-cell and spatial transcriptomic profiling decodes lineage plasticity and immune microenvironment remodeling in prostate cancer progression.

Yu H, Wang Y, He M, Chen Y, Bi J, Lin X, Cui X
Molecular cancer 2026 Feb 28;25(1)

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SOD1 lactylation impair its enzymatic activity by conformational change to aggravate intervertebral disc degeneration.

Zhang Y, Zhai Y, Liu C, Chen M, Zhang Y, Bian Z, Chang X, Hu Z, Li J, Zhang C, Ni Z, Xie Y, Chen L, Liu M, Li C
Nature communications 2026 Feb 28;17(1)

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Effect of lumbrokinase on a rat model of hyperlipidemia-induced erectile dysfunction.

Li X, Sun Y, Zhang X, Zhang Z, Han Z, Chen Y
Translational andrology and urology 2026 Feb 28;15(2):41

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Kynurenic Acid/GPR35 Signaling Protects the Infarcted Heart by Suppressing Macrophage mtDNA-Triggered cGAS-STING Activation.

Mao Y, Jiao J, Zhu X, Liu W, He S, Li N, Yang H, Li J, Tang T, Xia N, Cheng X
Antioxidants (Basel, Switzerland) 2026 Feb 27;15(3)

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Methadone maintenance therapy alters the expression of PLK1 and IFIH1 in patients with heroin addiction: a case-control study.

Zhang B, Sang Y, Aihemaijiang M, Feng L, Muhedaner Y, Dong M, Hu X
Psychopharmacology 2026 Feb 27;

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Uncovering the Potential Mechanisms of Ergothioneine in Neuroinflammation Through Network Pharmacology, Molecular Docking, Molecular Dynamics Simulation, and In Vitro Validation.

Cao D, Jia J, Yin Y, Lu W
International journal of molecular sciences 2026 Feb 26;27(5)

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Glibenclamide attenuates osteoarthritis by suppressing NLRP3 inflammasome activation in synovial macrophages through the MAPK pathway.

Ni J, Zhou H, Shen K, Xu H, Wang J, Liu J, Liu F
Journal of translational medicine 2026 Feb 26;24(1)

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Macrophage-derived IL-6 reprograms lipid metabolism to promote colorectal cancer development through USP14-mediated FASN deubiquitination.

Yunxin L, Xirui X, Xinyi Z, Chenjing W, Ting Z, Kanghui F, Haixia Y, Zude C, Wan H, Yubing Z, Xianjun F
Journal of translational medicine 2026 Feb 26;24(1)

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Chloroquine phosphate targets the MAPK-ERK pathway to inhibit ASFV SY-1 replication in vitro.

Mao H, Wang Y, Zhang K, Zhou W, Cheng C, Fang S, Wang L, Song Z, Sun X, Hu X, Zhang Y, Zou Z, Zhang Q, Zhao Y, Jin M
Virology journal 2026 Feb 26;23(1)

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Mazdutide Ameliorates Metabolic Dysfunction-Associated Steatotic Liver Disease by Modulating Endoplasmic Reticulum Stress, Improving Lipid Metabolism and Alleviating Inflammation.

Gan L, Duan L, Zheng X
Pharmaceuticals (Basel, Switzerland) 2026 Feb 26;19(3)

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DUSP26 protects against acute kidney injury by dephosphorylating p53 at serine 312.

Fu Y, Xiang Y, Han Y, Cai J, Duan S, Chen A, Dong Z
Nature communications 2026 Feb 26;17(1)

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An engineered linear cap-independent mRNA vaccine with intrinsic adjuvanticity induces potent anti-tumor immunity in mice.

Yu H, Yang Y, Lin P, Liu C, Wen Y, Huang Z, Fang Z, Hu Z, Huang S
Nature communications 2026 Feb 26;17(1)

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NPRL2 restricts porcine reproductive and respiratory syndrome virus replication by targeting viral Nsp1α for autophagic degradation.

Yi H, Wang S, Wang Q, Lu L, Xie E, Ye R, Wang H, Zhang G
Veterinary research 2026 Feb 25;57(1)

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MKRN2 enhances hepatocellular carcinoma proliferation through the p38 MAPK pathway.

Chen X, Yan Z, Du X, Zhang Z, Liu X, Zhang J, Hu L, He K, Wang J, Han Y
Human cell 2026 Feb 25;39(3)

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A peptide immunomodulator activates MST1 to expand and stabilize murine and human regulatory T cells for immune tolerance.

Wang Y, Liu X, Li X, Zhao L, Chen H, Gong X, Xu J, Zhang J, Liu Z, Sun Y
Science translational medicine 2026 Feb 25;18(838):eadz0672

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Deubiquitinase UCH-L1 confers paclitaxel resistance via stabilizing PKM2 to promote glycolysis in triple-negative breast cancer.

Chen X, Zhou X, Meng Y, Zhou Y, Zhang W, Yin L, Shen Y, Zhong J, Zhang T, Zu X
Cell death & disease 2026 Feb 25;17(1)

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Targeting G9a Exerts Pleiotropic Suppression in Triple-Negative Breast Cancer Cells: Cooperatively Inducing Pyroptosis and Apoptosis.

Li J, Zhang G, Liu T, Yan X, Ma M
Biomolecules 2026 Feb 25;16(3)

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Quercetin Attenuates Iron Overload-Induced Renal Injury via Activating Nrf2/xCT/GPX4 Signaling to Inhibit Ferroptosis.

Wang X, Li W, Yuan W, Wei Z, Yang Z, Zhang Z, Sun Z, Ji G, Hu H
Life (Basel, Switzerland) 2026 Feb 25;16(3)

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DNER as a novel protein contributes to HSCR pathogenesis: multi-omics combined Mendelian randomization analysis.

Liu W, Xu W, Huang J, Xu J, Fu Z, Yan H, Jia W, Yu H, Zheng B, Pan W, Chen X, Gao Y, Tian D
Pediatric research 2026 Feb 25;

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hnRNPA2B1 induces HBV cccDNA degradation by recruiting APOBEC3B.

Fu Z, Wang L, Sun Y, Ren C, Dou Y, Wang K, Fan Y, Yue X, Li C, Gao L, Liang X, Ma C, Wu Z
Nucleic acids research 2026 Feb 24;54(5)

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Cellular Mg(2+) decrease causes a distinctive NF-κB-dependent form of cell death.

Kawamura K, Ono K, Mishima E, Hashizume O, Conrad M, Miki H, Funato Y
Cell reports 2026 Feb 24;45(2):116964

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Hepatocyte PLAGL2 deficiency alleviates MASH through MYD88-licensed inactivation of inflammasome.

Duan R, Wang X, Wang Q, Zhou X, Gao S, Sun Y, Feng Q, Li Z, Yang Z, Ding J, Chen Z, Duan J, Yang Y
Cell reports 2026 Feb 24;45(2):116942

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A monoclonal antibody targeting the C-terminal of α-synuclein fibrils mitigates pathology in a Parkinson's disease model.

Zeng S, Zhang S, Gui X, Li D, Lv S, Dong H, Xu Q, Wu J, Ren H, Zhao Q, Long H, Yu Y, Hou S, Le W, Fan M, Liu D, Li D, Liu C
Cell reports 2026 Feb 24;45(2):116897

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Oncolytic adenovirus type 11-induced ferroptosis of esophageal squamous cell carcinoma cells involves in mitochondrial impairment and the mTOR pathway.

Si L, Zhao C, Chard Dunmall LS, Wang P, Cheng Z, Wang Y
BMC cancer 2026 Feb 24;26(1)

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Human FGF1(ΔHBS) Gene Therapy as Treatment for Metabolic Dysfunction-Associated Steatohepatitis in ApoE-KO Mice.

Li Y, Hui X, Gu C, Lin Q, Abdelbaset-Ismail A, Xu Z, Yadav S, Huang H, Xu J, Watson SE, Wintergerst KA, Cai L, Deng Z, Tan Y
Cells 2026 Feb 24;15(5)

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Preparation of Artemisia argyi-Derived Extracellular Nanovesicles and Their Protective Effects Against Oxidative Stress-Induced Senescence in Endometrial Stromal Cells.

Zheng X, Huang R, Liu Z, Liu T, Lin H, Yin L, Wu Q, Zhao M
Bioengineering (Basel, Switzerland) 2026 Feb 24;13(3)

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ANGPTL8 accelerates bone loss in diabetic mice by promoting osteoclastic differentiation and inhibiting osteoblastic differentiation through AMPK pathway-mediated metabolic reprogramming.

Tuo P, Mu W, Bai X, Wang S, Hu L, Xu Y, Mao R, Liu Y, Yuan Y, Zhang Q, Guo X, Ma S, Wang X
Cellular and molecular life sciences : CMLS 2026 Feb 23;83(1)

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Identification of Paraptosis-Related Renal Cell Carcinoma Subtypes, Construction of a Prognostic Signature, and Determination of Tumor Microenvironment Landscape Using Bioinformatic Analysis and Experimental Verification.

Qin M, Chen M, Gan Y, Feng X, Huang P, Meng F, Yang Y
Current issues in molecular biology 2026 Feb 23;48(2)

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A novel mechanism of chlorogenic acid against type 2 diabetes-induced diabetic retinopathy: suppressing ferroptosis via NRF2/xCT/GPX4 and STAT3 signaling.

Zheng J, Wang X, Guo Y, Feng L
Naunyn-Schmiedeberg's archives of pharmacology 2026 Feb 23;

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Lactate-induced miR-7-5p/TRIM33 reprograms metabolic flux to suppress tumor growth and viral reactivation.

Xu Y, Min X, Zhang Z, Zhang Y, Chen X, Wang X, Zhu C, Robertson E, Zhang Q, Tong Y, Zhang L, Wang Y, Cai Q
Molecular therapy : the journal of the American Society of Gene Therapy 2026 Feb 23;

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From machine learning to causal insight: a robust 12-gene signature to distinguish sepsis risk from systemic inflammatory response syndrome.

E B, Chen L, Luo S, Xie L, Wang X, Wang W, Xia Y, Yang X, Fu G, Wang J
European journal of medical research 2026 Feb 21;

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[Veratric acid relieves oxidative stress and DSS-induced colitis in mice by activating the Nrf2/HO-1 signaling pathway].

Yin L, Zhang K, Qiao T, Niu M, Yin L, Liu X, Geng Z, Li J, Hu J
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2026 Feb 20;46(2):403-411

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[Lactobacillus plantarum alleviates lead exposure-induced learning and memory impairment in mice by regulating bile acid metabolism and inhibiting hippocampal NLRP3 expression].

Li L, Yu W, Tan M, Li Y, Liu A, Meng X
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2026 Feb 20;46(2):271-277

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Aurkb deficiency disrupts microglial development, homeostasis and hinders remyelination following cuprizone-induced demyelination.

Yan W, Xiang D, Du L, Zhu D, Jia Q, Liu Y, Wang S, Liu L, Guan H, Zhao Y, Jiang G, Gao S, Wang H
iScience 2026 Feb 20;29(2):114718

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Late ad libitum feeding reverses early feed restriction-induced immune deficit in broilers.

Wang F, Feng J, Zhu Z, Nan S, Jing W, Yao M, Dou L, Wang D, Liu X, Sun X, Nie C
iScience 2026 Feb 20;29(2):114698

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LncRNA SLC16A1-AS1 cooperates with NSUN2 to stabilize GRP78 mRNA via m5C modification in gastric cancer.

Zheng B, Zhao W, Jin Y, Sun W, Li Y, Zhang Q, Li Y, Wang J, Chen D, Ren K, Zhang W, Chen Y, Yuan L, Wang XJ, Yang F, Chen J
iScience 2026 Feb 20;29(2):114614

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Consensus machine learning identifies cell death gene signature for carotid artery stenosis diagnosis.

Guo C, Fang K, Cai G, Liu Y, Zhang W, Zhang L, Wu Z, Luo M, Shu C
iScience 2026 Feb 20;29(2):114397

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Epigenetic control of microglial mitochondrial immunity by KAT7 drives Alzheimer's disease pathogenesis.

Liu Y, Fan M, Ye Y, Cheng HY, Sun S, Qiu Z
bioRxiv : the preprint server for biology 2026 Feb 20;

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YBX1 Modulated Corneal Neovascularization Induced by Alkali Burn via m5C-Dependent Regulation of the STAT3/HIF-1α/VEGFA Axis.

Yang Z, Yan Y, Deng Q, Gao Y, Mao J, Ke L, Wan S, Yang Y
Investigative ophthalmology & visual science 2026 Feb 2;67(2):42

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PRMT3-mediated post-translational adaptation to fasting regulates metabolic flexibility.

Huang Z, Liu X, Chen X, Zhou Y, Chen Q, Liu Y, Zhu H, Cheng K, Feng Y, Dong M, Song L, Wang L, Liu S, Shan T, Kuang S, Dong Y, Vidal-Puig A, Zhang Y, Jia Z
Nature communications 2026 Feb 2;17(1)

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PARP-1 couples β-catenin/TCF4 signaling to epithelial-mesenchymal transition in endometriosis.

Zhang L, Li X, Kong L, Hou X, Li B, Zhang Y, Wang J
Scientific reports 2026 Feb 2;16(1):6940

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Asparagine sensing by TBK1 controls its phase separation to drive antiviral innate immune responses.

Du J, Li C, Chai L, Zhao F, Lv L, Yang Z, Zhao Z, Gong R, Yang L, Wu M, Nie M, Jia J, Kang D, Gao C, Zhao W, Jia M
Molecular cell 2026 Feb 19;86(4):722-739.e8

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The HEAT repeat protein MROH7 regulates the inflammatory macrophage response via LBP acetylation.

Zhang H, Fu J, Guo Y, Liu S, Mei X, Zeng X, Ren W
Cell chemical biology 2026 Feb 19;33(2):169-182.e5

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Research on the mechanism of CRMP4-mediated cytoskeletal actin polymerization in promoting invasive migration of stromal cells in endometriosis.

Song L, Guo J, Yin L, Guo H, Ji G, Zhang Y, Hu R
Journal of translational medicine 2026 Feb 19;24(1)

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Differential activation of NF-κB pathway by Escherichia coli and Bacteroides fragilis lipopolysaccharides affects blood-brain barrier permeability.

Liu X, Ju G, Wang X, Liu R, Ding Q, Yuan S, Qian J
Archives of microbiology 2026 Feb 19;208(4):203

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Mitochondrial bioenergetics-SASP crosstalk determines senolytic efficacy in therapy-induced senescence.

Llop-Hernández À, Verdura S, López J, Martin-Castillo B, Menendez JA, Cuyàs E
Cell death discovery 2026 Feb 19;12(1)

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De novo purine synthesis reprograms the macrophage inflammatory response and the immune response in sepsis.

Haskó G, Liu L, Németh ZH, Wagener G, Akcan U, Arif M, Pacher P, Kelestemur T
Research square 2026 Feb 19;

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Ring finger protein 213 regulates B-cell receptor signaling, metabolism, and development in B lymphocytes.

Zhang Z, Xiang N, Liu Q, Li Y, Wang L, Yang X, Liu J, Zhang L, Lu L, Liang Y, Yang L, Qi X, Liu C
Signal transduction and targeted therapy 2026 Feb 18;11(1):59

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LC-MS/MS-based metabolomics analysis and experimental verification reveal the mechanism of Dahuang Mudan Decoction inhibition with the proliferation of colorectal cancer cells.

Feng C, Yang C, Gao W, Liu Y, Wei J, Shen C, Chen W, Li X
Naunyn-Schmiedeberg's archives of pharmacology 2026 Feb 18;

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Diosmetin, an active ingredient of Schizonepeta tenuifolia, alleviates acne by regulating inflammation and oxidative stress.

Pan Y, Sun R, Thomas ER, Pan S, Yang L, Wang W, Chen L, Li X
Naunyn-Schmiedeberg's archives of pharmacology 2026 Feb 18;

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Mitochondrial protein Mrpl4 is required for zebrafish intestinal development.

Li L, Cheng X, Liu C, Fang S, Lin L, Su Y, Zhao L
FEBS letters 2026 Feb 18;

---

Proteomics landscape of early T-cell precursor acute lymphoblastic leukemia reveals deficient oxidative phosphorylation signatures.

Liu M, Chen T, Lin X, Wu B, Shi F, Liu J, Chen Y, Zeng T, Hou S, Pan Q, Wang X, Yao Y, Yang W, Zhang Y, Huang J, Jin J, Zhu Y, Wang H
Cell reports. Medicine 2026 Feb 17;7(2):102586

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p53 regulates early mucosal immunity via antigen presentation in zebrafish intestine post-SVCV vaccination.

Zhao Z, Wei XF, Zhao L, Xia JY, Li YY, Jia YJ, Zhu B
Cell communication and signaling : CCS 2026 Feb 17;24(1)

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ΔNp63α drives serine synthesis to promote carboplatin resistance in NSCLC.

Deng L, Yang X, Zhang J, Zhou X, Ma R, Wu Z, Chen H
Cell death & disease 2026 Feb 17;17(1):227

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Group A streptococcal PerR coordinates iron and zinc homeostasis through Dpr, aiding in bacterial fitness during endothelial cell infection.

Su MS-W, Lee C-J, Cheng Y-L, Tsai W-J, Chiang-Ni C, Wang K-Y, Hsieh Y-C, Liao C-C, Wu J-J
mSystems 2026 Feb 17;11(2):e0163625

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Akkermansia muciniphila alleviates experimental colitis through FXR-mediated repression of unspliced XBP1.

Bu F, Zhang K, Song B, He L, Lu Z, Yuan X, Chen C, Jiang F, Tao Y, Zhang W, Zhang D, Chen Y, Wang Q
mSystems 2026 Feb 17;11(2):e0158925

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ALDH1L1 suppresses the replication of porcine epidemic diarrhea virus by degrading viral nucleocapsid and envelope proteins.

Wang J, Zeng Y, Liu Y, Sun H, Gao A, Zheng D, Tong W, Yu H, Zheng H, Tong G, Cao X, Kong N, Shan T
Journal of virology 2026 Feb 17;100(2):e0193325

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S100A10 promotes glycolysis and malignant progression of CCA by activating the HK2/ERK signaling pathway.

Wang Y, Chen W, Liu W, Zhang X, Wang Y, Dai N
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2026 Feb 17;

---

Mechanism of action of two potent LRRC8/VRAC channel inhibitors.

Granados ST, Song R, Añazco F, Vermejo JM, Rao Y, Concepcion AR
Research square 2026 Feb 17;

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An Extracellular Matrix-Producing Subset of Cancer-Associated Fibroblasts Drives Chemoresistance in Breast Cancer via SRC Activation and G0S2 Upregulation.

Hofer I, Kieffer Y, Mencattini A, Croizer H, Mhaidly R, Descroix S, Le Tourneau C, Kamal M, Lamy C, Bonneau C, Cottu PH, Vincent-Salomon A, Martinelli E, Mechta-Grigoriou F, Parrini MC
Cancer research 2026 Feb 16;86(4):1054-1072

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LAPTM5 potentiates airway remodeling by regulating MAPKs-mediated airway smooth muscle cells' dysfunction.

Jiang L, Ying Y, Jin H, Zhou T
Mammalian genome : official journal of the International Mammalian Genome Society 2026 Feb 16;37(1):36

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HSP90α facilitates the dephosphorylation of DRP1 at the Ser637 residue, thereby promoting NLRP3 inflammasome activation and exacerbating brain injury in sepsis.

Yang H, Zhou X, Zhang B, Shan Y, Jin Y, Pan E, Xu D, Fan L, Zhao P, Sun Y, Dong J
Free radical biology & medicine 2026 Feb 16;244:45-67

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Redox switch C674 in SERCA2 triggers Ca(2+)-calcineurin-MCU-Drp1 cascade and pulmonary vascular remodeling.

Chen H, Qiu YX, Xie YF, Chen X, Xiang YY, Zhang HL, Yu WM, Hu PP, Wang LT, Wu FH, Tong XY
Free radical biology & medicine 2026 Feb 16;244:380-394

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Unveiling a Novel Mechanism in Noise-Induced Hearing Loss: Oxeiptosis-Mediated Regulated Cell Death of Cochlear Hair Cell.

Zhang X, Qi M, Zhang P, Gao Z, Wu Z, Wang W, Yang R, An X, Lu F, Wang R, Zhu Q, Zha D
Neuroscience bulletin 2026 Feb 16;

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Tocilizumab-loaded nanoparticles block IL-6R and reduce edema after intracerebral hemorrhage.

Ma S, Lin Q, Xue D, Li L, Liu H, Guo H, Sun F, Dong J, Guo C, Han L, Zhao J, Ma J, Wang Q, Guo W, Ge S, Tian Y, Zhou J, Qu Y
Journal of advanced research 2026 Feb 16;

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RasGRP3 Promotes RAP1B Activity to Inhibit Endothelial Inflammation and Alleviate Atherosclerosis in High-Fat Diet-Fed ApoE(-/-) Mice.

Zhang B, Wei Z, Zou Q, Qiao H
Inflammation 2026 Feb 14;49(1)

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USP30-mediated Deubiquitination of Hexokinase 2 controls the metabolic fate of glucose and tumor progression.

Haowei Z, Li X, Liao W, Qin X, Jiang Y, Yang H, Zeng H, Li Y, Xie W, Zhang Y, Xu N
Cell death & disease 2026 Feb 14;17(1):225

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Nonthermal radiofrequency radiation promotes hematopoietic stem and progenitor cells function by regulating Ca(2+) efflux.

Lv Z, Zhao K, Li J, Li S, Zhao X, Xu A, Wu Y, Gao H, Li J, Sun H, Xue Y, Li S, Xiang S, Yang X, Li C
Stem cell research & therapy 2026 Feb 14;17(1)

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Combining xQTL and genome-wide association studies from diverse populations improves druggable gene discovery.

Lorincz-Comi N, Song W, Chen X, Paz IR, Hou Y, Zhou Y, Xu J, Martin W, Barnard J, Pieper AA, Haines JL, Chung MK, Cheng F
Nature communications 2026 Feb 14;17(1)

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Houttuynia cordata Polysaccharide Alleviates Hepatic Ischemia-Reperfusion Injury by Regulating Macrophage Polarization via Inhibiting the TLR4/NF-κB Signaling Pathway.

Yu B, He D, Chen Z, Zhou Y, Zhou J, Wang T, Qiu Q, Chen Z, Ma X, Zhu J, Zheng S, Qiu T
Biomedicines 2026 Feb 14;14(2)

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Sesquiterpenoids target IFIT family proteins and LIMK1: potential implications for the tumor microenvironment and macrophage infiltration.

Li X, Zeng X, Li X, Liu Y, Tang J, Zhang L, Wei L, Mao J
BMC cancer 2026 Feb 13;26(1)

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Signal recognition particle-dependent secretome in humans.

Miller SC, Tikhonova EB, Rodríguez-Almonacid CC, Bustamante C, Weintraub ST, Karamyshev AL
Scientific reports 2026 Feb 13;16(1)

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MMP1 is a promising prognostic, therapeutic and immunological biomarker for pancreatic cancer: evidence from bioinformatics analysis and biological experiments.

Wang S, He K, Liu M, Zhou J, Wen Y, Cheng Y
BMC cancer 2026 Feb 12;26(1)

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Lactate derived from macrophages drives skin dermal fibroblasts phenotypic remodeling via MCT1-primed histone H3 lysine 23 lactylation in hypertrophic scar.

Yuan Y, Xiao Y, Zou J, Luo L, Li M, Shen K, Wei L, Zhang Y, Wang P, Chen Y, Zhuo S, Zhang H, Song S, Jia Y, Wang K, Jiang S, Guan H, Hu D
Nature communications 2026 Feb 12;17(1)

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EMF-induced mesenchymal stem cell migration is mediated by SOCE-dependent calcium influx and modulated by ROCK signaling.

Zhao P, Ou J, Bai L, Zhang M, Li X
Journal of bioenergetics and biomembranes 2026 Feb 11;58(1)

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The promoting roles of GLP1R and GIPR in stemness maintenance and multiple lineage-specific differentiation of PDLSCs.

Shen Y, Zhang M, Yang T, Wu Y, Qiu Y, Zhang L, Li F, Chen M, Chen Q, Wei W, Li H, Shen Y
Cellular & molecular biology letters 2026 Feb 11;31(1):22

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Coptis chinensis extracellular vesicles loaded with CA1-siRNA promote endothelial repair and stent restenosis therapy by regulating the PADI2 and NF-κB pathway.

Wang X, Liu Y, Li W, Hao J, Zhao Z, Fan H, Wu X, Liu X, Xu H, Yu T, Liu M, Guo M, Li Y
Journal of nanobiotechnology 2026 Feb 11;24(1):157

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FADS1 contributes to anesthesia/surgery-induced cognitive impairment by aggravating omega-6 fatty acid metabolic disruption in aged mice.

Chen Z, Wu Q, Ma J, Shi Y, Zhang Q, Wu H, Zhang Y, Li Z, Ruan X, Xiong L, Cong P, Tian L
Journal of neuroinflammation 2026 Feb 11;23(1)

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Desaminotyrosine promotes tuft cell expansion and integrates intestinal type 2 immunity.

Zang W, Zhou Z, Shen Y, Zhang B, Chen X, Yue W, Li X, Cai Y, Chen J, Bian J, Huang L, Li H, Dai Y, Yang H
mBio 2026 Feb 11;17(2):e0328925

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DDX41 facilitates PD-L1-mediated immune escape in OSCC via the phase separation and activation STING pathway.

Tian Z, Cui H, Sun S, Lan Z, Zhong P, Liu W, Li B, Chen H, Zhu Z, Yang Y, Yu J, Lian J, Zhao Y, Yu G
NPJ precision oncology 2026 Feb 11;10(1)

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Pulmonary macrophage-targeted RNAi and mRNA co-delivery via SORT lipid nanoparticles enhances immunotherapy in lung cancer.

Liang Q, Peng Y, Zhao L, Yang Z, Chen X, Li J, Wu Z, Chen K, Zhou B, Liu Y, Hu B, Qu C, Zhang M, Gao S
Journal of controlled release : official journal of the Controlled Release Society 2026 Feb 10;390:114519

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Therapeutic mechanism of Qingre Tonglin capsules (QRTL) in CNP via inflammasome suppression.

Song W, Fang X, Zhang R, Zhuang X, Chen H, Wang J, Han Y, Sun J, Zhu Z, Liu W, Bao HW, Li L
Journal of ethnopharmacology 2026 Feb 10;356:120828

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Deciphering the eRNA landscape and revealing target aberrant pathways in prostate cancer.

Yu C, Wen Y, Li Y, Song B, Hu Y, Meng Z, Yan Z, Du W, Rong H
BMC cancer 2026 Feb 10;26(1)

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SDC1(+) CAFs secreting CTGF drive tumour metastasis via FGFR3 signalling in cancers.

Gao GF, Ruan ZH, Zhang SB, He S, Li YQ, Lyu JL, Liu Y, Tan XL, Wang YJ, Liu ZW, Lv GZ, Chen G, Yu JH, Wei PP, Zhao JF, Sun ZT, Zhao Z, Shi Y, Liao W, Chen SW, Zhang N, Kuang DM, Guan XY, Peng RJ, Cai MY, Yao K, Bian XW, Ding PR, Luo CL, Bei JX
Gut 2026 Feb 10;

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Structural characterization and anti-hepatic fibrosis effects of a novel polysaccharide from Astragalus complanatus seeds.

Zhu ZF, Wang SY, Liu XF, Liu N, Dong DC, Qi YC, Li N, Wang N, Tan J, Jia C, Cai RQ, Li XQ, Cao W
Carbohydrate polymers 2026 Feb 1;373:124661

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An intrabody targeting PHD2 protects mice against acetaminophen-induced liver injury by attenuating ferroptosis.

Ren Z, Wang Y, Cheng C, Zhang Y, Liu Y, Wei Y, Liu Z, Zhang J, Shi Z, Yu J, Hu W, Ye J, Wang J, Qiu S, Li G
Free radical biology & medicine 2026 Feb 1;243:260-275

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Blood-brain barrier disruption and neuroinflammation in the hippocampus of a cardiac arrest porcine model: Single-cell RNA sequencing analysis.

Jiang T, Li Y, Liu H, Sun Y, Zhang H, Zhang Q, Tang S, Niu X, Du H, Yu Y, Yue H, Guo Y, Chen Y, Xu F
Neural regeneration research 2026 Feb 1;21(2):742-755

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Bromodomain-containing protein 4 knockdown promotes neuronal ferroptosis in a mouse model of subarachnoid hemorrhage.

Lu P, Zhang F, Yang L, He Y, Kong X, Guo K, Xie Y, Xie H, Xie B, Jiang Y, Peng J
Neural regeneration research 2026 Feb 1;21(2):715-729

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T-cell apoptosis is more susceptible to overactivated neutrophils delivered-NETs-MPO/NE complex.

Lu C, Shao L, Li H, Gao X, Mei Y, Sun B
International immunopharmacology 2026 Feb 1;170:116100

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Melittin-loaded solid lipid nanoparticles inhibit pulmonary fibrosis via the NOVA2-TGF-β/Smads signaling pathway.

Yuan X, Zhang T, Liu Z, Zhang S, Hang Y, Huang J, Huang W, Shen Y, Zhang X, Qian Y, Li L
International immunopharmacology 2026 Feb 1;170:116050

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Inflammation-induced impairment of synaptic plasticity accelerates atherosclerosis co-depression disease: insights from bioinformatics analysis and transcriptomics.

Zhao Y, Luo Q, Ren P, Zhang R, Wen Y, Lai H, Fan Y, Liu X, Zhou J, Wu X
Cell & bioscience 2026 Feb 1;16(1)

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Integrated multi-omics and causal inference framework with experimental validation reveals key drivers of air pollution-induced acute kidney injury.

Liu J, Zeng D, Fu L, Huang Z, Wang Y, Deng F, Deng Z
International journal of surgery (London, England) 2026 Feb 1;112(2):2879-2900

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Discovery of ferulic acid carbamate derivatives as dual-targeting agents of BuChE and Nrf2 for Alzheimer's disease.

Lao K, Li Y, Xiao Y, Sun Y, Dai Y, Li H, Yang Y, Zhang Y, Wang J, Li W, Gou X, Guan L
Journal of enzyme inhibition and medicinal chemistry 2026 Dec;41(1):2645483

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Design, synthesis and anti-breast cancer activity evaluation of 6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine-based PARP1/ATR dual inhibitors.

He ML, Wang ZH, Yao X, Ye LL, Du BQ, Wang CC, Chen YH, Wang XX, Luo H, Gao Y, Ye XY
Journal of enzyme inhibition and medicinal chemistry 2026 Dec;41(1):2627053

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Integrating virtual screening and molecular dynamics simulations to identify emodin as a PYCR1 inhibitor modulating docetaxel sensitivity in prostate cancer.

Liu S, Lao Y, Cheng L, Xiao X, Ma L, Wang W, Zhao K, Li W, Zhou Z, Li Q, Tao Y, Liu S, Dong Z
Journal of enzyme inhibition and medicinal chemistry 2026 Dec;41(1):2622725

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Discovery of 2-phenylethyl chromones as potent and selective CYP1B1 inhibitors.

Chen W, Ye W, Long Y, Zhang Y, Zhou W, Wang W
Journal of enzyme inhibition and medicinal chemistry 2026 Dec;41(1):2598738

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Urolithin A alleviates vascular remodeling through mitochondrial SIRT3-mediated SOD2 deacetylation and antioxidation in hypertensive rats.

Dai M, Wang YM, Dong HK, Xu XY, Wang JX, Zhu GQ, Zheng F
Redox report : communications in free radical research 2026 Dec;31(1):2622255

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EP300 attenuates ferroptosis and stimulates proliferation, migration, and fibrosis of keloid fibroblasts via YY1/GPX4 axis.

Jin J, Wang K, Lu C, Yao C, Xie F
Cell cycle (Georgetown, Tex.) 2026 Dec;25(1):1-16

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HIV-1 Vpr activates microglia by upregulating m6A modification through ubiquitin-proteasome pathway-mediated degradation of the demethylase ALKBH5.

Peng Q, Li W, Qian F, Zhu Y, Hu S, Shi Y, Xia Y, Liu W, Shu X, Wan P, Liu Y, Sun B
Virulence 2026 Dec;17(1):2645908

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Lactoferrin blocks orthopoxvirus entry via heparan sulphate and regulates host antiviral pathways.

Tian L, Qin H, Li S, Zhang M, Zhuang L, Hong B, Liu K, Li M, Li S, Wang Y, Song L, Liu Y, Wang Y, Liu H, Tong Y, Fan H
Emerging microbes & infections 2026 Dec;15(1):2631205

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The potential of human milk oligosaccharides in ameliorating traumatic brain injury-induced cognitive impairment in mice.

He D, He R, Duan W, Li G, Kang Q
Future science OA 2026 Dec;12(1):2622241

---

Phosphoglucose isomerase directs the inflammatory response, calcium influx and fibroblast migration in keloids.

Lu YY, Lu CC, Wang WT, Wu CH
Future science OA 2026 Dec;12(1):2615968

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EGCG-loaded nanoparticles attenuate post-SAH white matter injury by targeting HO-1/S100A10 to suppress oxidative stress-induced reactive astrocytes.

Lang D, Zheng Y, Zhang J, Li Z, Niu M, Wang J, Wang X, Huang L, Xue J, Li L, Chen Y
Redox report : communications in free radical research 2026 Dec 31;31(1):2664955

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Overconsumption of fructose aggravates acute GVHD by inducing gut dysbiosis and promoting macrophage-mediated inflammatory response.

Wu K, Yu H, Cao K, Dai B, Yuan Y, Qian X, Zhong H, Qu Y, Jiang H, Chen T
Gut microbes 2026 Dec 31;18(1):2642459

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Inhalable PD-L1-engineered hybrid cellular vesicles suppress excessive neutrophil activation and restore mitochondrial homeostasis to alleviate ischemia-reperfusion lung injury and pneumonia.

Yuan H, Wang W, Ma J, Li H, Reis RL, Chen Y, Xu X, Yuan Y, Li Y, Yan L, Fan Z, Liao Y, He J
Bioactive materials 2026 Aug;62:319-341

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A coenzyme-based "interface-welding" hydrogel coating for titanium implants promotes diabetic osseointegration by regulating mitochondrial dynamics.

Duan Q, Geng W, He T, Yang J, Li K, Yang F, Fu Z, Liao X, Luo H, Zhao P, Cai K
Biomaterials 2026 Aug;331:124115

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Dietary advanced glycation end products induced anxiety- and depression-like behaviors in female C57BL/6 mice and the ameliorative effects of quercetin.

Ma T, He Z, Yang G, Cai J, Qin LQ, Xia Y, Wan Z
The Journal of nutritional biochemistry 2026 Aug;154:110363

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Pan-cancer analysis of NTRK2 (TRKB) and the anticancer effect of its inhibitor Lucitanib in glioma.

Li X, Xue R, Wei C, Zhang S, Sun Y, Hu Y, Zhang Y
Computational biology and chemistry 2026 Aug;123:108985

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Antagonism of GPR75 inhibits gestational diabetes mellitus-induced placental tissue injury by preventing activation of the NLRP3 inflammasome.

Tong Q, Hu M, Guan Y, Song F
Tissue & cell 2026 Aug;101:103515

---

Developmental lead exposure induces neurotoxicity via glycolytic failure, glial activation, and miR-144 downregulation in male rat offspring.

Zeid SMA, Mahmoud MO, Boshra SA, Gomaa SB
Tissue & cell 2026 Aug;101:103462

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Beauvericin promotes autophagy and mitophagy by activating NIPSNAP2.

Zhao X, Zhang R, Ma Y, Yu T, Li J, Liu A, Hu J, Wu J, Zhang L, Ye M, Wu B, Dang Y
Bioorganic chemistry 2026 Aug 5;177:109885

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Shh-S100A10 axis curbs neuronal PANoptosis after ischemic stroke.

Wang L, Tang H, Wen J, Yang Q, Huang J, Zhao Y, Ren Y, Yang Q
Neural regeneration research 2026 Aug 1;21(8):3579-3587

---

Three-dimensional cell culture in vitro could better recapitulate the biological behavior of cells in vivo.

Qi Z, Yang S, Fu C, Xu J, Li Q, Yan J, Shen A, Hu B
Tissue & cell 2026 Apr;99:103246

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PRKD3 Overexpression May Improve Survival and Suppresses Proliferation in Colorectal Cancer.

Zhang B, Chang C, Chen J, Cao Y, Chang Y, Liu L, Li W, Wang G
Cancer reports (Hoboken, N.J.) 2026 Apr;9(4):e70543

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Targeted recruitment of USP15 enhances CTLA4 surface levels and restricts its degradation.

Querques F, Ciampani V, Tey PY, Kutilek VD, Kadic E, Clague MJ, Urbé S
Life science alliance 2026 Apr;9(4)

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Podocyte TLR4 deletion alleviates diabetic kidney disease through prohibiting PKCδ/SHP-1-dependent ER stress and relieving podocyte damage and inflammation.

Li Z, Tan D, Lin J, Zhang T, Liu B, Zhao B, Liang D, Li L, Wei X, Lv Z, Wang R, Hu M
Journal of advanced research 2026 Apr;82:845-862

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The GOLM1-ACLY pathway regulates macrophage-secreted EFEMP1 via H3K27ac modifications to drive tumor progression.

Zhen L, Min M, Mo X, Zhao G, Li H, Liu M, Wan L, Yang X, Huang L, Zhang Y, Gao Q, Zhong H, Qiang G, Wu F, Xie Q, Wei C, Zhao R
Journal of advanced research 2026 Apr;82:765-783

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MeCP2 dysregulation inhibits mitophagy and impairs neural development in cortical organoids.

Zhou J, Liu Y, Jing X, Peng H, Li F, Cao L, Li W, Li R, Zhang J, Wang X, Lian J, Tong D, Huang C
Journal of advanced research 2026 Apr;82:429-448

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Fruit-Derived Citri Reticulatae Semen Extract Attenuates Alzheimer's Disease Neuroinflammation and Cognitive Impairment via Modulation of the PI3K/Akt/FoxO1 Pathway.

Li S, Zhang X, Zhang P, Wang X, Yang Y, Qin D, Law BY, Pan Y, Tang Y
Molecular nutrition & food research 2026 Apr;70(7):e70452

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Chromosome 1 Open Reading Frame 35 Drives Colorectal Cancer Progression by Enhancing Tumor-Intrinsic Proliferation and CD8(+) T Cell Suppression.

Zhang S, Yang C, Xu X, Lan L, He Z, Chen J, Wang C
MedComm 2026 Apr;7(4):e70707

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Discovery of a First-in-Class Murine Double Minute 2-Recruiting Positive Transcription Elongation Factor B PROTAC Degrader With Selective Antitumor Activity.

Guan X, Xie L, Guo H, Ma L, Zhou J, Luo L, Yang H, Wu Y, Liu J, Wang Y, Huang X, Liu J, Zhang Y, Chen W, Chen Y, Xu L, Han X
MedComm 2026 Apr;7:e70723

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OSBPL3 promotes LUAD metastasis and glycolysis through transcriptional upregulation of PLAU via NFE2L2.

Zhang Q, Zhang J, Li J, Chen S, Liu Y, Li K, Guo M
Translational oncology 2026 Apr;66:102693

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Targeting PTGS2/NF-κB Pathway: MG-132's Role in Reducing Ischemic Stroke Injury.

Wang YS, Huang YC, Wang YQ, Zheng YX, Gao YR, Wu MX, Gao FH, Wang HZ, Liu K, Yan L
Biochemical genetics 2026 Apr;64(2):2546-2564

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Piperlongumine Inhibits Malignant Progression of Esophageal Squamous Cells Through the PI3K/AKT Signaling Pathway.

Wang J, Chu Y, Hu G, Liang S, Cui Y, Zuo J, Luo Z, Chen X, Wang X, Yu Z, Zhang Z, Wang X
Biochemical genetics 2026 Apr;64(2):2254-2271

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Rhomboid Domain Containing 2 (RHBDD2) is Upregulated and Responds to Cisplatin-Induced DNA Damage in Esophageal Cancer.

Ding Y, Zhou L, He X, Li L, Wang X
Biochemical genetics 2026 Apr;64(2):1877-1894

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The glycolytic metabolite phosphoenolpyruvate restricts cGAS-driven inflammation to promote healthy aging.

Song Z, Hu H, Zhang W, Zheng X, Liang L, Zhao B, Song G, Li J, Li S, Wen Y, Zhang B, Wang W, Deng G, Zhang C, Jiang H, Hu S, Tu H, Wu M, Li H
Nature aging 2026 Apr;6(4):831-848

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Mantis shrimp saddle-mimetic amorphous calcium (zinc) phosphate/chitin scaffolds with superior mechanical properties and bioactivity for bone regeneration.

Zhao Z, Gao J, Vecchio KS, Cao L, Liu X, Wang H, Yang R, Tang P, Li M, Zhang X
Bioactive materials 2026 Apr;58:738-754

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Designed bone-targeting ROS-responsive nanoplatform for precision glycolysis inhibition in postmenopausal osteoporosis.

Wu Q, Miao J, Chen Y, Yang Y, Liang H, Yu C, Wang C, Tu Y, Wu Y, Xu Y, Yang X, Kwan KYH, Shi C, Wang X, Xu J, Jin H
Bioactive materials 2026 Apr;58:1-18

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DUSP26: Unveiling a critical molecular mediator and therapeutic target in developmental dysplasia of the hip‑associated secondary osteoarthritis.

Wang E, Zhang H, Wu D, Ali S, Ji X
International journal of molecular medicine 2026 Apr;57(4)

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Quercetin reduces expression of ATP‑binding cassette transporters by regulating the PTEN/PI3K/AKT signaling pathway in breast cancer cells.

Fu W, Lin L, Li J, Qin F, Chen C, Cai Y, Cai Y, Huang Y, Yang W, Zhu S
Oncology reports 2026 Apr;55(4)

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Deguelin inhibits growth and prolactin synthesis in prolactinomas by targeting the PI3K/AKT/CREB3L1 pathway and ornithine decarboxylase.

Gong L, Liu CX, Cheng JH, Guo J, Li B, Wang HY, Liu M, Wang JL, Li XJ, Fang QY, Yi ZY, Li CZ, Zhang YZ, Xie WY
Acta pharmacologica Sinica 2026 Apr;47(4):999-1014

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PAK4 functions as an immune suppressor by reprogramming the phosphatidylcholine metabolism of CD8 + T cells within the glioblastoma tumor microenvironment.

Yao L, Gao H, Su Z, Zhao G, Tang L, Feng S, Ma Y, Zhang X, Feng M, Qian J, Li Y, Sun T, Liu J, Wang H, Zhou Y
Oncogene 2026 Apr;45(15):1296-1311

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PRSS22 inhibits HMOX1-mediated ferroptosis and induces osteopontin cleavage to promote M2 macrophage polarization and colitis-associated carcinogenesis.

Kuang Z, Su Q, Liang W, Shen K, Xie J
Oncogene 2026 Apr;45(14):1275-1286

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Dexamethasone promotes neutrophil ROS-mediated tumor killing through the glucocorticoid receptor.

Liu Z, Sun R, Li Y, Zhang Z, Huang P, Zhou Y, Hou P, Mu W, Melino G, Li P, Shi Y, Shao C
Oncogene 2026 Apr;45(13):1175-1186

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PMM2 interacts with TRIM28 to recruit E2F4 and promote KIFC3-mediated tumor glycolysis and colorectal cancer progression.

Peng Z, Ma B, Song Z, Zhao Y, Yang Y, Liu Y, Li C, Zhang Y
Oncogene 2026 Apr;45(12):1145-1160

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UCP2 in Glioblastoma Cells Regulates Mitochondrial Metabolic Reprogramming to Mediate Immunophenotypic Repolarization of Tumor-Associated Macrophages and Immunotherapy.

Du H, Wang X, Sun J, Liu X, Zhao L, Guo H, Wu J, Yang J
Journal of biochemical and molecular toxicology 2026 Apr;40(4):e70808

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Unlocking an Efficient SOD-to-CAT Catalytic Relay in a MOF Nanozyme via Dopamine-Driven Interfacial Nanoreconstruction for Osteoarthritis Therapy.

Li Z, Wu B, Li W, Marsili E, Tang K, Sun K, Cao Z, Zhang Y, Huang H, Li X, Wang G
Advanced materials (Deerfield Beach, Fla.) 2026 Apr;38(19):e72747

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Biomimetic nanoplatform with multienzyme cascade activity boosting ROS generation and immune activation feedback for tumor therapy.

Bai C, Hu P, Ni Z, Xie J, Cai F, Wang J, Wang X, Guo D
Materials today. Bio 2026 Apr;37:103001

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A dual-functional Janus nanofibrous membrane as an immunomodulatory barrier for periodontitis regeneration under diabetic conditions.

Wang F, Wang Y, Sheng J, Zhang K, Cao Y, Han X, Yan K, Wang X
Materials today. Bio 2026 Apr;37:102869

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Ganoderma lucidum polysaccharide-decorated extracellular vesicle enables synergistical antitumor immunotherapy.

Ouyang Z, Li S, Zhang A, Ye S, Ye W, Wen G, Wei T, Cai B, Liu H
Materials today. Bio 2026 Apr;37:102832

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Immediate tumor killing and long-term anti-tumor immunoreaction induced by Bufalin-loaded phototherapeutic Janus membrane in CRC postoperative therapy.

Yu X, He Y, Zhong J, Li Y, Zhu Y, Chen Y, Yin J, Yuan Z, Yin P
Materials today. Bio 2026 Apr;37:102824

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Dual-responsive PDA-HP hydrogel enables mitochondria-targeted mild photothermal therapy for spinal cord repair.

Li Y, Hu J, Ran B, Zhong H, Zhong N, Zhong Y, Fu X, Liu X, Wu G, Zhong Q, Li J
Materials today. Bio 2026 Apr;37:102783

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Ultrasound-activated piezoelectric Silk-PVDF hydrogel reprograms the osteoimmune microenvironment via NRF2 signaling for accelerated bone regeneration.

Mo G, Qing L, Zhang C, Huang L, Yan H, Lu S, Zhang Y, Chen W, Xiang X, Wang N, Han G, Li Y, Jiang L, Zhang J
Materials today. Bio 2026 Apr;37:102779

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Thyroid Hormone Synthesis Without Thyroglobulin.

Young C, Zhang X, Kellogg AP, Fonseca TL, Pena K, Beyzin A, Liao XH, Cicatiello AG, Zhang H, Bianco AC, Refetoff S, Arvan P
Thyroid : official journal of the American Thyroid Association 2026 Apr;36(4):441-450

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Viperin inhibits coronavirus replication by targeting non-structural protein 8 to disrupt replication-transcription complex assembly and RNA-dependent RNA polymerase activity.

Li J, Wang Q, Du L, Chen H, Hu J, Zhou Y, Peng Q, Shi Y, Zhou J, Gu J
International journal of biological macromolecules 2026 Apr;359:151843

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Inhibition of voltage-dependent anion channel 1 aggregation protects pancreatic beta-cell mitochondria from glucose toxicity.

Yao C, Zeng X, Huang S, Cheng H, Huang H, Zou Z, Mou B, Youssef M, Liu M, Wei Y, Liu J, Li H, Xiong Q, Shang X
International journal of biological macromolecules 2026 Apr;356:151598

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Mechanism insights into the role of Smc5/6 in HBV inhibition.

He L, Shen H, Zhao A, Pan Y, Ma J, Ouyang Z
International journal of biological macromolecules 2026 Apr;354:151307

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Emodin modulates the NLRP3/GSDMD pathway to alleviate Fusobacterium necrophorum-induced pyroptosis in the interdigital skin fibroblasts of dairy Cows.

Zhang A, Liu M, Tang Y, Wang R, Ruan H, Zhu T, Ge Y, Xu E, Zheng J
International journal of biological macromolecules 2026 Apr;353:151331

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HSP70 preserves brain microvascular endothelial integrity under heat stress associated with suppressed JNK-mediated apoptosis and mitophagy.

Zhou M, Li H, Wan M, Ji Z, Liu Z, Wan Z, Cai J, Shi J, Qiu X, Zhang X
International journal of biological macromolecules 2026 Apr;353:151239

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Role and mechanism of tetrahedral DNA nanostructures in the repair of urethral injury in rats.

Guo C, Li J
Molecular medicine reports 2026 Apr;33(4)

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miRNA‑29a inhibits the proliferation of HUVECs by regulating the ITGB1/β‑catenin/c‑Myc pathway.

Sun Q, Chen W, Zhang S, Zhong X, Wu Y, Qian Y, Zhu L, Zhang T, Li W
Molecular medicine reports 2026 Apr;33(4)

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Targeted depletion of intratumoral bacteria using PEGylated metronidazole to augment cancer treatment efficacy.

Wang X, Wang Y, Guo C, Guo R, Zuo W, Liu C, Wang J, Gao C, Zhang L, Yuan W, Ma J
Biomaterials 2026 Apr;327:123772

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Multifunctional hydrogel delivery of mesenchymal stem cell secretome suppresses neutrophil extracellular trap formation and promotes diabetic wound healing via PGE2/BMAL1 pathway.

Lin L, Liang X, Xu Z, Li Y, Guo Z, Liu L, Liu H, Cai Q, Chen Y, Yu Z, Li Y
Biomaterials 2026 Apr;327:123764

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A multifunctional manganese-based nanozyme platform for synergistic hypoxia alleviation and cholesterol depletion to potentiate STING-mediated cancer immunotherapy.

Liu S, Shao S, Huang Z, Xue P, Yan S, Cao M, Zeng X
Biomaterials 2026 Apr;327:123760

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Inhibition of Transglutaminase 2 Preserves Blood-Brain Barrier Integrity and Improves Neurological Outcomes After Experimental Traumatic Brain Injury in Mice.

Yang J, Zhang L, Qiu X, Wang J, Yan R, Ye J, Peng J, Jiang Y
CNS neuroscience & therapeutics 2026 Apr;32(4):e70887

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ANGPT2/Tie2 Enhances H3K18la-Mediated Macrophage M2 Polarization to Promote Endothelial Cell Proliferation in the Chronically Ischaemic Brain.

Tai C, Ling C, Yang Y, Mo N, Yao C, Lv S, Zhang B, Wang H, Chen C
CNS neuroscience & therapeutics 2026 Apr;32(4):e70879

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Porcine USP18 inhibits Japanese encephalitis virus replication by regulating the type I interferon signaling pathway.

Shi H, Li X, Zhou X, Wang H, Qin W, Jin H, Zhao A, Yang S
Veterinary microbiology 2026 Apr;315:110936

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ANKFY1 suppresses PDCoV replication by degrading viral nsp8 protein via p62-dependent selective autophagy.

Xu Y, Zhang Y, Zhu H, Yu X, Lou J, Liu M, Liu G, Bai J, Jiang P, Yang Z, Wang X
Veterinary microbiology 2026 Apr;315:110927

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HIF-1α/Netrin-4 Axis Mediates RIPC-Induced Angiogenesis and Neurogenesis After Ischemic Stroke.

Feng Z, Liu Z, Tang S, Pan M, Zhu K, Liu Y, Wang C, Yao R, Wei X, Liu H
Journal of cellular and molecular medicine 2026 Apr;30(7):e71121

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Dapansutrile preserves pancreatic beta-cell function by regulating insulin vesicle membrane fusion and mitochondrial homeostasis.

Wu Y, Fu H, Zhu M, Yao Y, Jin L, Lin X, Zhou J
Diabetes, obesity & metabolism 2026 Apr;28(4):3054-3069

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Zinc protects against neuroinflammation after spinal cord injury by regulating mitophagy-dependent mtDNA-cGAS-STING signaling.

Jin F, Song Z, Deng Y, Yang H, Yuan Y, Guo Z, Zhao H, Mei X
Free radical biology & medicine 2026 Apr;247:286-302

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Remimazolam alleviates blood-brain barrier damage by regulating the PI3K/AKT signaling pathway in sepsis-associated encephalopathy mice.

Xu B, Wang X, Liu S, Guo Y, Dong Q, Tao Y, Zhang M, Ni P, Xie Y
Brain research bulletin 2026 Apr;237:111824

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MCL1 promotes porcine epidemic diarrhea virus replication by modulating arachidonic acid metabolic pathway.

Shang H, Yang S, Sun M, Zhao Y, Guo R, Wang W, Qian B, Li Y, Hu M, Bian X, Cao Q, Li C, Fan B, Li B
PLoS pathogens 2026 Apr;22(4):e1014170

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Nanomagnetic Hyperthermia Sensitizes Gemcitabine Chemosensitivity in Pancreatic Cancer by Inhibiting HSPB1 to Amplify ACSL4-Mediated Ferroptosis.

Ren J, Wu S, Su T, Li H, Ding J, Chen F, Mo J, Li J, Wang Z, Han L, Wu Z
Small (Weinheim an der Bergstrasse, Germany) 2026 Apr;22(22):e14973

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Subconjunctival injection of novel antioxidant nanoparticles inhibits neovascularization after corneal injury.

Zhou J, Hou S, Wang X, Zhu L, Kang Z, Xing K, Zhang J
Nanomedicine (London, England) 2026 Apr;21(8):1081-1090

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YTH Domain Family 2 Promotes Tubal Factor Infertility through Reducing H3K4me1 Methylation of CYLD by KMT2D.

Shao L, Wang N, Yan Y, Tan Y, Huang Y, Wu Q, Tan Q, Liu L
Applied biochemistry and biotechnology 2026 Apr;198(4):3250-3267

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From computational prediction to in vitro experimental validation: Identifying active compounds in longan leaves and their anti-colorectal cancer mechanisms.

Wei J, Xie Y, Qin J, Ouyang Y, Qin H, Zhou D, Wang H, Wei M, Wu L
Fitoterapia 2026 Apr;190:107178

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Recoding multiple rare codons enables the simultaneous incorporation of up to five distinct noncanonical amino acids.

Fang Y, Yu W, Li J, Lao L, Yuan Y, Chen Y, Ding W, Lin S
Nature chemistry 2026 Apr;18(4):695-706

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Targeting SLC5A2 suppresses colorectal tumour development by enhancing NK cell activity through extracellular vesicle-dependent MICA/B signalling.

Xiao J, Wu J, Deng F, Liu C, Chen Y, Shen K, Wang C, Lin W, Liu W, Ning Z, Zhou R, Zhao L
Clinical and translational medicine 2026 Apr;16(4):e70657

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TLR3 as a PANoptosis-related gene: a potential diagnostic biomarker and therapeutic target for diabetic retinopathy.

Zhao J, Yang M, Shi Y, Zhan D, Yuan X
3 Biotech 2026 Apr;16(4):133

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Cordyceps cicadae polysaccharides ameliorate ulcerative colitis by modulating the gut microbiota and regulating the bile acid/FXR/NF-κB signaling pathway.

Zhou S, Su F, Gao Q, Wang M, Duan J, Li J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:158007

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Resveratrol dual efficacy in high-altitude hypoxia and NAFLD: inhibits ferroptosis by modulating key proteins, including HIF-1α, ACSL4, and TfR1.

Zhao M, Mu H, Ji Q, Song J, Zheng F, Liu T, Li W, Wang R
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157992

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Kakkalide promotes spinal cord injury repair by regulating microglial M2 polarization via mitophagy.

You T, Dai B, Ding X, He Z, Peng J, Tao S, Ye L, Song T, Fan Z, Chen N
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157985

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Xanthoxylin alleviates dextran sulfate sodium (DSS)-induced colitis by targeting macrophage infiltration via the tumor necrosis factor (TNF) /nuclear factor-kappa B (NF-κB) signaling pathway.

Chen Y, Chen Z, Li J, Zhao R, Chen Q, Zhong C, Lu M, Shi Y, Wang L, Bao L, Zuo Z, Mao X, Wu F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157971

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Huodan Qinghua formula inhibits CD36 membrane localisation via the TGR5-DHHC4 pathway to ameliorate lipotoxic damage in diabetic cardiomyopathy.

Fan X, Ge J, Liang Y, Yan Z, Geng X, Li M, Sun X, Zhu B, Shang W, Jia Y, Zhao Y, Kang Y, Zhang Z, Hu Y, Zhang J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157761

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Sulforaphane ameliorates DSS-induced colitis and secondary liver injury in mice: Proposed mechanism in the SCFAs-FFAR2/3-macrophage polarization axis.

Ren J, Jiang X, Yu G, Wu W, Chen M, Zhao Y, Yang M, Zou Z, He C
The Journal of nutritional biochemistry 2026 Apr;150:110239

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Food-derived chlorogenic acid prevents aortic aneurysm and dissection by nutritional restore branched-chain amino acid dyshomeostasis.

Ma ZX, Yin ZQ, Feng ZA, Xie XP, Li A, Fu SH, Yue Q, Wang S, Ma LK, Duan YJ, He DQ, Wu JF, Zhang S, Zhao ZW
The Journal of nutritional biochemistry 2026 Apr;150:110211

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ANKRD62 Modulates NF-κB Signaling to Promote Proliferation and Migration in UCEC.

Hao C, Li Y, Li Z, Fu L, Lin S
Cancer medicine 2026 Apr;15(4):e71822

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Flexible Bioactive Glass-Fiber-Reinforced Recombinant Collagen Sponge for Versatile Hemostasis, Antibacterial Protection, and Functional Skin Regeneration.

Fan Z, Li M, Cai K, Xie Z, Lu B, Zhang M, Zhang Y, Wang J, Gu C, Zheng K, Chen T
Advanced healthcare materials 2026 Apr;15(16):e04908

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Jiawei Danxuan Koukang and Its Component Kaempferol Alleviate Oral Submucous Fibrosis by Restoring Epithelial-Fibroblast Homeostasis and Suppressing Neutrophil Recruitment via the ANXA1/FPR2 Axis.

Xiao Y, Tan Y, Liu Y, Chen R, Zhou T, Hu Z, Tan J
Food science & nutrition 2026 Apr;14(4):e71785

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NLRP3 Inflammasome Activation Mediates Coronary Artery Lesions in Kawasaki Disease by Inducing Endothelial Cells Pyroptosis and Glycocalyx Injury.

Zheng R, Yue J, Chen Q, Xie J, Wen L, Duan N, Shang J, Zhu S, Huang L, Zou Y, Song X, Wu X, Feng Q
Immunity, inflammation and disease 2026 Apr;14(4):e70433

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ADAMTS2 Modulates Inflammation, Autophagy, and Barrier Integrity Through PI3K/AKT/mTOR Signaling in LPS-Induced Acute Respiratory Distress Syndrome.

Gao S, Lyu T, Quan Y, Tao Y, Wang W, Xu X
Immunity, inflammation and disease 2026 Apr;14(4):e70429

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Lactate modulates microglial M2 polarization via H3K9 lactylation in ischemic stroke.

Li B, Xu K, Yu J
Journal of translational internal medicine 2026 Apr;14(2):276-293

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Vericiguat as a Novel Ferroptosis Inhibitor Alleviates Doxorubicin-Induced Cardiotoxicity.

Han H, Luo T, Liu C, Ou W, Zhang Y, Zhang Z, Huang S, Luo W, Wen J, Wang N, Zhang Z, Liu H, Wang X
Basic & clinical pharmacology & toxicology 2026 Apr;138(4):e70219

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Coronavirus Nsp3 Hijacks CLTC to Modulate Autophagosome Nucleation for Promoting DMV Formation and Viral Replication.

Xu J, Li H, Liu P, Jiao Z, Zhang D, Su Z, Niu S, Zhang J, Shi Y, Peng G
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(24):e21626

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ACSL1-Dependent Microglial Lipoimmunometabolic Reprogramming Underlies Cognitive Deficits in Alcohol Use Disorder.

Hao L, Cao XR, Li BQ, Zhao FY, Wang JM, Gao RK, Cao ZP, Du ZX, Wang HQ
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(21):e19760

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Tumor-Associated Macrophage-Derived CXCL1 Promotes Endometrial Cancer Progression Through the CXCR2/NF-κB Pathway.

Xia R, Qi D, Ji B, Dai Y, Kong X
Cancer science 2026 Apr;117(4):1026-1042

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Gut microbial ammonia enhances colonic acetylcholine levels to regulate intestinal motility.

Chen H, Wang Z, Zhao Y, Yang W, Huang J, Yu Z
Nature microbiology 2026 Apr;11(4):907-919

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An inducible Flad1 knockout mouse model establishes its essential role in energy metabolism, muscle function and adult survival.

Xie B, Qi Q, Wang Y, Liu J, Liu Y, Shen Y, Guo Y, Wang R, Li J, Yan C, Jin Z, Zhou T, Xia Q, Zhang W, Li A
Biochemical and biophysical research communications 2026 Apr 9;808:153438

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Hydrogen Sulfide Donor Featuring Dual-Modal Imaging for the Theranostic Management of Drug-Induced Liver Injury.

Wang Y, Yuan F, Wu C, Ning L, Zhao Y, Shen JW, James TD, Zhang J, Guo Y
Journal of medicinal chemistry 2026 Apr 9;69(7):8036-8050

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Discovery of a Selective DNMT1 Degrader with a Unique Molecular Glue Mechanism as a Potential Therapeutic Agent for Acute Myeloid Leukemia.

Ma L, Zhang K, Wang Y, Zheng N, Gu X, Li C, Li W, Li N, Liu Y, Lu Z, Lin J, Wang X, Xu J, Huang Z, Zhao X, Li D, Liu S, Yang G
Journal of medicinal chemistry 2026 Apr 9;69(7):7756-7781

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Oncolytic virus hijacks GOT1 and pyrimidinosomes to fuel pyrimidine synthesis for replication in tumor cells.

Tang N, Gong Y, Zhao C, Niu Y, Tan L, Song C, Qiu X, Liao Y, Yu S, Ding C, Lin S, Sun Y
Tumour virus research 2026 Apr 9;21:200342

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Perforin-2 enhances antigen-specific CTL immune response by promoting cross presentation.

Zha ZK, Deng CJ, Shen LJ, Liu LZ, Huang YX, Li YH, Lv L, Zhang K, Chen LS, Chen FE, Li SA
Cell death & disease 2026 Apr 9;17(1)

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Avian herpesvirus-specific LORF5 is a late gene, interacts with 19 viral and 111 host proteins, critical for virulence of Duck plague virus.

Li H, Cheng A, Wang M, Zhang W, Yang Q, Ou X, Sun D, He Y, Tian B, Wu Z, Zhang S, Huang J, Wu Y, Yu Y, Zhang L, Zhao X, Zhu D, Chen S, Jia R, Liu M
Poultry science 2026 Apr 9;105(7):106924

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The integrated stress response suppresses PINK1-dependent mitophagy by preserving mitochondrial import efficiency.

Yang M, Mo Z, Walsh K, Liu W, Irahal IN, Arnoult D, Guo X
Nature communications 2026 Apr 9;

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Astrocytic calcium-dependent enzyme PAD2 governs microglia activity to exacerbate amyloid pathology via citrullinated vimentin.

Zhang J, Huang Y, Chen Y, Zhang Y, Chen J, Huang Y, Zhong H, He H, Dai X, Yan X, Chen W, Ye Q, Chen X, Zhang J
Immunity 2026 Apr 9;

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Citrulline Modulates Milk Fat Metabolism via the RTN3-FABP5 Axis in Bovine Mammary Epithelial Cells.

Cheng J, Ren K, Shi Y, Wang L, Li L, Yang Y, Kuang T, Pan S
Journal of agricultural and food chemistry 2026 Apr 8;74(13):11079-11091

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African swine fever virus hijacks lipolysis induced by chaperone-mediated autophagy to upregulate fatty acid β-oxidation and promote viral replication.

Yang X, Xiong X, Liu H, Wen X, Shi X, Ma H, Wang R, Cao W, Yang F, Ru Y, Tian H, He J, Guo J, Han S, Zhu Z, Zheng H
mBio 2026 Apr 8;17(4):e0336825

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E3 ubiquitin ligase TRIM21-mediated K48-linked ubiquitination of ALDH2 rs671 mutant promotes adverse cardiac remodeling.

Han T, Wen X, Guo Y, Zhao X, Zhang J, Chen Y, Xu F
JCI insight 2026 Apr 8;11(7)

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Maresin1 mitigates morphine analgesic tolerance via the Lgr6 pathway.

Tian X, Ye J, Shen C, Chen X, Xiao J, Lian C, Li L, Zeng R, Fu X, Fang W, Zhan G, Shangguan W, Xu Y, Qian C, Gao Y, Jin S
Progress in neurobiology 2026 Apr 7;261:102916

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Computational-experimental integration reveals PPARγ/Nrf2-GPX4 dual-targeting by combined selenomethionine-magnolol as a novel therapy for sarcopenic obesity.

Li Z, Liu B, Zhou L, Chen N, Wang Y, Yang S, Fan X, Wang Y, Chen X
Free radical biology & medicine 2026 Apr 7;251:243-255

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Erianin facilitates pyroptosis in endometrial cancer via targeting m6A reader YTHDF1.

Shu W, Zhou X, Zhao R, Dong K, Shen X, Chen G, Cheng S, Zhang Q, Zhou T, Zhang J, Zhang T, Yu S, Li H, Yao Y, Liu Y, Zhang J, Wang H
Chinese medicine 2026 Apr 7;21(1)

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SIRT3-mediated mitochondrial fatty acid oxidation protects against hepatic lipid deposition in fatty liver hemorrhagic syndrome.

Cao P, Chen J, Zeng C, Hu Y, Yuan J, Guo X, Cao H, Zhang C, Zhuang Y, Hu G
Poultry science 2026 Apr 7;105(7):106901

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Tongnao Decoction Exerts a Treatment Effect on Ischemic Stroke by IL-6/PI3K/Akt/GSK-3β Pathway: Based on the Network Pharmacology and Molecular Docking.

Gan J, Cong Y, Li L, Ma F, Yang X, Deng Y, Liu Y, Wu Y, Jiang H, Chen Z, Li W, Zhu Y, Wu M
Assay and drug development technologies 2026 Apr 7;:1540658X261438876

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KAT2B inhibits cholangiocarcinoma proliferation by binding with histone demethylase KDM6B.

Qiu R, Xu Z, Meng H, Wang Y, Wu Q, Zeng L, Zhao H, Mao Z, Weng Q, Tu J, Zhao Z, Chen M, Yang Y, Ji J
Biochimica et biophysica acta. Molecular basis of disease 2026 Apr 6;1872(6):168242

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Targeting the Hedgehog Signaling Pathway in the Retina Using Quercetin-Loaded Lipid Nanoparticles for Myopia Control.

Zhao L, Guo B, Dong X, Du Y, Xu Z, Song Y, Feng J, Zhang A, Qu Y, Song J, Bi H
Translational vision science & technology 2026 Apr 6;15(4):3

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Genetic identification of the FcδR complex: TRβV12-4 as the IgD-binding domain targeted for immunotherapy in rheumatoid arthritis.

Hu X, Han C, Huang D, Xu J, He J, Wu T, Dong M, Zhao J, Li T, Wu Y, Wei W
Journal of advanced research 2026 Apr 6;

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Design, synthesis, and investigation of anti-Alzheimer's activity and molecular mechanisms of phosphatidylserine derivatives.

Lin Y, Lin X, Zhu J, Li M, Xi Y, Lu D, Zhang Y, Fu L, Jiang F
European journal of medicinal chemistry 2026 Apr 5;307:118676

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Targeting SAT1 alleviates high glucose-induced tubular ferroptosis and fibrosis: implications for diabetic kidney disease.

Tang Y, Wang S, Wang Y, Zhang T, Liu Y, Di Y
Histochemistry and cell biology 2026 Apr 5;164(1)

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Legumain Restrains Granuloma Formation by Inhibiting mTORC1/STAT1-Mediated M1 Macrophage Polarization in Sarcoidosis.

Liu M, Han Y, Xie B, Zhu L, Xu W, Han Y, Liao Y, Gao S, Jiang D, Geng J, Li Z, Hu Y, Dai H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 3;:e20635

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Fatty acid scavenging enables cancer escape from KRAS inhibition.

Yuan Z, Lin B, Wang C, Miao Y, Zhang D, Meng Z, Wang G, Lowy AM, Karin M, Yang F, Sun B, Su H
bioRxiv : the preprint server for biology 2026 Apr 3;

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GPD1-mediated neuronal lipotoxicity drives aconitine-induced mitochondrial collapse and lethality.

Jiang C, Hu W, Deng S, Huang Y, Wang L, Yang Z, Li Y, Li P, Wu H
Chemico-biological interactions 2026 Apr 29;434:112104

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Targeting the SIN1 mediated TTK/LDHA-H3K18la-GLUT3 axis disrupts metabolic-epigenetic crosstalk and suppresses progression in hyperglycolytic breast cancer.

Zhao Z, Jia W, Li Z, Shi S, Zhou J, Ning C, Yu Z, Liu X, Cao X, Zheng H, Wang X, Wang X, Yu Y
Cancer letters 2026 Apr 28;644:218328

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Preparation of M2 macrophage membrane hybrid lipid nanoparticles based on microfluidic device for atherosclerosis treatment.

Liu Q, Qiao L, Peng XF, Chang SQ, Fang X, Li YJ, Huang NP
Colloids and surfaces. B, Biointerfaces 2026 Apr 28;265:115753

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Triple-Targeted Peptide-Photosensitizer-Drug Conjugate Enables NIR-II Imaging-Guided Multimodal Therapy Against Osteosarcoma.

He X, Liang X, Yu J, Rong J, Hu J, Xu C, Cai Z, Chen J, Zhang Y, Pu X, Sun P, Wu H, Sun B
ACS nano 2026 Apr 28;20(16):12577-12595

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Lysosomal dysfunction contributes to lead (Pb) and high-fat diet (HFD)-induced neuronal apoptosis: A link with cathepsin B.

Yuan Y, Liu M, Zhai M, Wu M, Zhang W, Xin Y, Ba Y, Zhang Y, Han L, Gao L, Huang H
Neurotoxicology 2026 Apr 28;114:103462

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Ferroptosis-STING co-activation drives GzmB(+)CD38(+)CD8(+) T-cell expansion to overcome lymphoma immunosuppression.

Zhu X, Zhang D, Zhang J, Fang Z, Zhang Y, Jiang C, Xu R, Hu X
Biomaterials 2026 Apr 27;334:124250

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FTO-mediated m6A demethylation of TRIM21 regulates macrophage polarization and attenuates myocardial ischemia-reperfusion injury.

Wan Z, Ding Y
Immunologic research 2026 Apr 25;74(1)

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OLFM4 mediating ischemia/reperfusion-induced kidney injury by regulating renal tubular epithelial cells ferroptosis via GPX4.

Zhang Z, Wang Y, Mu Z, Zhao S, Zhang T, Zhang Z, Sun S, Bai M
Molecular biology reports 2026 Apr 25;53(1)

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SEPHS2 loss reprograms cancer metabolism from oxidative phosphorylation to gluconeogenesis via PCK1 stabilization.

Zhang Y, Zhang Q, Wei B, Wang W, Chen X, Ding W, Li C, Ye Y, Xu J, Zhang W, Li L, Mai F, He W, Du X, Zhao K, Zhao Z, Huang J, Niu Y, Zhang Y, Dai L, Zhang B, Xia S
Cell reports 2026 Apr 25;45(5):117297

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Adissp activates insulin-independent glucose disposal and energy expenditure in white fat to treat diabetes and cardiometabolic disease.

Huang L, Liu P, Chen Q, Hu K, Li S, Lee A, Wabitsch M, Zhu LJ, Yu Q, Davis R, Czech MP, Wolfe SA, Wang YX
Science advances 2026 Apr 24;12(17):eaed2780

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Succinylation modification on NFS1 ameliorates the glucose starvation-induced ferroptosis through maintaining mitochondrial iron homeostasis in oral squamous cell carcinoma cells.

Ling H, Qing L, Zuo L, Wang H, Cai X, Liu Y, Tian H
Biochimica et biophysica acta. Molecular basis of disease 2026 Apr 23;1872(6):168276

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Gut microbiota-derived trimethylamine-N-oxide protects pulmonary vascular barrier integrity via Vav guanine nucleotide exchange factor 3 (VAV3)-mediated cytoskeletal remodelling in acute lung injury.

Wang X, Zeng W, Bai Q, Zhong K, Luo Q, Deng J, Cen C, Wang K, Li R, Li J, Zhang J, Ye T, Fang N, Chen X, Wang T
British journal of pharmacology 2026 Apr 23;

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Ophiopogon japonicus Polysaccharides Promote Microbial Production Of Chenodeoxycholic Acid To Alleviate Ulcerative Colitis in Mice by Inhibiting the STING1-Related NF-κB Pathway.

Gao X, Zhang C, Zhao Z, Chen Y, Lei H, Cao Z, Yu W, Lin W, He Y, Li X, Xiang Q, Zhang Z, Zhang L, Chen G
Journal of agricultural and food chemistry 2026 Apr 22;74(15):12087-12101

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Lycium Barbarum Polysaccharide Attenuates Staphylococcus aureus-Induced Mastitis via the Gut Microbiota-Derived Indole-3-Propionic Acid/AhR-IL-22-STAT3 Axis.

Li K, Ran X, Ding H, Han J, Zhang L, Wang X, Guo W, Li Y, Fu S, Bi J
Journal of agricultural and food chemistry 2026 Apr 22;74(15):12038-12053

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Müller cell membrane biomimetic nanocarriers promote cell proliferation via Wnt/JAK-STAT signaling.

Chen S, Qi X, Chen Y, Li B, Yang Q, Li Z, Deng Z, Li H, Ji D
Journal of controlled release : official journal of the Controlled Release Society 2026 Apr 22;395:114943

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CAR-M2 immunotherapy resolves renal fibrosis via revascularization and apoptosis of profibrotic Cxcr2(+) endothelial cells.

Zhao W, Zhou X, Zhao X, Tian H, Su Y, Zhao S, Liu M, Zhang Q, Chen L, Li X, Liu D, Li J, Li L, Wang Y, Li X, Yan J, Chen W, Liu B, Zhu C, Zeng W
Cell reports. Medicine 2026 Apr 21;7(4):102698

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Establishment of a passive-transfer mouse model of anti-NMDAR encephalitis and delineation of the PI3K-AKT-HIF-1α Axis in antibody-induced neuronal injury.

Li H, Zhang S, Shu Y, Zhao Y, Qiu W, Long Y, Wang Y
Journal of neuroimmunology 2026 Apr 21;417:578943

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Dermal fibroblast-targeted trans-amplifying RNA nanotherapeutics for skin extracellular matrix regeneration.

Cui H, Hu H, He X, Cui H, Ni Q
Journal of controlled release : official journal of the Controlled Release Society 2026 Apr 21;395:114947

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Multi-Ion Channel Nanomedicines Targeting Zinc Transporter 1/ATPase Copper Transporters Disrupt Copper/Iron Homeostasis to Enhance Tumor Immunotherapy.

Ma G, Li Y, Li X, Yu D, Chao M, Li J, Guo J, Wang K, Liu Z, Sun R, Gao F
ACS nano 2026 Apr 21;20(15):11801-11821

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Simultaneous expression of three G genotypes of VP7 proteins in a recombinant porcine rotavirus confers protective immunity against multiple rotavirus infections.

Cheng X, Deng H, Bian X, Wang J, Wang C, Han N, Zhou J, Zhu X, Zhang X, Yang X, Tao R, Li B
Journal of virology 2026 Apr 21;100(4):e0201525

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Palmitic Acid Promotes Antiviral Innate Immunity via ZDHHC20-Mediated CMPK2 Palmitoylation.

Wang Y, Cui Z, Zhang Y, Li Z, Cao X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 21;:e75209

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MCT4 deficiency suppresses tumor incidence and metastasis by downregulating IGF1 expression and enhancing anti-tumor immunity.

Wang S, Guo H, Feng L, Wang X, Zhang Y, Li X, Zhou X, Ma N
Communications biology 2026 Apr 20;9(1)

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Antioxidant Activity of Flavonoid Glabranin by Upregulating Antioxidant Gene Expression via MEK/ERK and PI3K/Akt Pathways in Human Neuroblastoma SH-SY5Y Cells.

Nakatsuji M, Shibano M, Fujimori K
Neurochemical research 2026 Apr 20;51(3)

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Coptis chinensis Franch. Suppresses Invasive Pulmonary Aspergillosis by Augmenting NADPH-Dependent Neutrophil Extracellular Traps via Dual Modulation of Complement Activation and Gut Microbiota.

Jiang Z, Zhou L, Wang J, Sun H, Cai L, Yin H, Zhu H, Li M, Wang Z
Current issues in molecular biology 2026 Apr 20;48(4)

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Critical Role for Malic Enzymes in MYC-Mediated Cellular Adaptation to Glutamine Depletion.

Si Y, Li W, Chen Y, Yuan J, Hu C, Liu Y, Li L
Metabolites 2026 Apr 20;16(4)

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Sympathetic denervation alters pulmonary microbiota diversity and composition in mice.

Zhang J, Yang X, Xie L, Liu Q, Zhang X
International microbiology : the official journal of the Spanish Society for Microbiology 2026 Apr 20;

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Single-Cell Lineage Tracing Uncovers Resistance Signatures and Sensitizing Strategies to FLT3 Inhibitors in Acute Myeloid Leukemia.

Eriksson J, Zheng S, Popa M, Bao J, Dai J, Wang W, McCormack E, Vähärautio A, Tang J
Cancer research 2026 Apr 2;86(7):1724-1738

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Pyruvate is a natural suppressor of interferon signaling by inducing STAT1 protein pyruvylation.

Zuo Y, Wang Q, Tian W, Wang X, Zheng Z, He W, Zhang R, Zhao Q, Miao Y, Yuan Y, Zhang T, Cui Q, Zhang Y, Liu C, Zhou H, Zheng H
Cell 2026 Apr 2;189(7):1975-1989.e19

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Regulation of short-term declarative memory by selective activation of the locus coeruleus-retrosplenial cortex dopaminergic pathway and its pathological alterations in Parkinson's disease.

Yan Y, Gao L, Qiang X, Qiu Y, Shen Y, Mu C, Tang C
Progress in neuro-psychopharmacology & biological psychiatry 2026 Apr 2;146:111680

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PINK1 and STUB1 pathway orchestrates peroxisomal selective autophagy by PEX13 depletion.

Jo DS, Park NY, Kim AK, Bang S, Kim YH, Bae JE, Noh K, Kim JH, Lee MJ, Choe SK, Kim PK, Chung J, Lee KS, Cho DH
Cell death and differentiation 2026 Apr 2;

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SIRPA suppresses integrin-dependent virus endocytosis.

Yan Z, Iyer K, Li M, Jung KH, Hu CT, Ansin N, Sarute N, Gowen BB, Ross SR
bioRxiv : the preprint server for biology 2026 Apr 18;

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PBX3 regulates mast cell parthanatos via TOP2A mediated DNA damage in allergic rhinitis.

Wu S, Zhu X, Xie W, Liu J, Li C, Wang M, Peng H
iScience 2026 Apr 17;29(4):115426

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Multi-omics integration reveals that pyrimidine metabolism in lung adenocarcinoma drives an immunosuppressive microenvironment.

Liu M, Li H, Xu S, Zhou Y, Yao M, Shi J, Zhong L
iScience 2026 Apr 17;29(4):115326

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CGF induces ROS-mediated metabolic reprogramming and mitochondrial dysfunction to suppress colorectal cancer progression.

Jiang J, Zhang X, Sun Y, Chen J, Yuan B, Li X, Chen X, Chen X, Li R
iScience 2026 Apr 17;29(4):115273

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Insufficient erythrocyte-derived S1P: A pathogenic driver and diagnostic biolipid for tumor progression.

Li Z, Huang W, Yao Z, Wang J, Xiao W, Guo Q, Chen C, Xie T, Yang Z, Liu Q, Kellems RE, Wu M, Xia Y
iScience 2026 Apr 17;29(4):115216

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KIAA1429 promotes clear cell renal cell carcinoma progression by regulating MYC mRNA stability.

Zhu X, Shen C, Zhang Y, Chen X, Zhang W, Zheng B, Chen Z
iScience 2026 Apr 17;29(4):115198

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Single-cell multi-omics sequencing reveals cell-specific transcriptomic and chromatin accessibility profiles in gut microbiome metabolite butyrate-produced pain modulation.

Tao R, Liu S, Crawford J, Kramer P, Bender S, Tao F
International journal of oral science 2026 Apr 17;18(1)

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FAAH initiates a positive feedback loop to promote lung adenocarcinoma progression through inhibition of ferroptosis.

He X, Tang C, Jiang T, Yang C, Zhang X, Ju Z, Zhao J, Wei R, Wang T, Xiong Y, Jia L, Zhang X
Cell death and differentiation 2026 Apr 17;

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Bisphenol F impairs spermatogenesis via UCP2-related oxidative stress and autophagy dysregulation.

Liu G, Lv J, Zhang J, Sun K, Wang Z, Li X, Li Y, Il D, Lian T, Altyn S, Jiang Z
Ecotoxicology and environmental safety 2026 Apr 15;315:120113

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Discovery of novel Keap1-targeting hydrophobic tag (HyT) tethering degraders with potent Nrf2 activation activity.

Li Z, Liu M, Zhao H, Zhang W, Wang L, Zhang Y, Xu J, Shen T, Ren D, Wang X
European journal of medicinal chemistry 2026 Apr 15;308:118700

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Structure-based discovery of a novel allosteric activator of ATG4B for the treatment of triple-negative breast cancer.

Jin W, Li Z, Li Z, Song J, Liu H, Liu Q, Gao F, Zhang L
European journal of medicinal chemistry 2026 Apr 15;308:118686

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IL-5 promotes airway remodeling in asthma by mediating epithelial-mesenchymal transition via the AKT/NLRP3 pathway.

Zhao L, Lin Y, Dou M, Su H, Han L, Wu J, Lu Y, Bao W, Zhang M
International immunopharmacology 2026 Apr 15;175:116422

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Notopterol attenuates atherosclerosis by promoting macrophage cholesterol efflux via targeting KEAP1/NRF2 interaction.

Qin Y, Meng J, Chen Y, Zhang W, Yi J, Wang S
International immunopharmacology 2026 Apr 15;175:116404

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Lithocarpus litseifolius and trilobatin ameliorate diabetic nephropathy through alleviating carbonyl stress by inhibiting AGEs/RAGE/NF-κB pathway.

Chen XM, Chen JX, Chen XM, Gao YX, Zeng CY, Chen DY, Xiang XQ, Hao XT, Wang SM, Tang D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr 15;156:158204

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‌An mRNA vaccine confers enhanced protection against herpes simplex virus through an IFN-I-dependent pathway.

Zhao W, Sun L, Wang P, Zhao Q, Li Y, Li Y, Shi H, Xing M, Dai W, Zhou D
NPJ vaccines 2026 Apr 15;

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Small-molecule inhibition of γ-glutamyl carboxylase reveals a novel anticoagulant strategy.

Shen G, Song D, Li S, Chen X, Richter CE, Dong S, Guo Y, Liu H, Shen Y, Hao Z, Stafford DW, Shavit JA, Cao Q, Tie JK
Blood advances 2026 Apr 14;10(7):2363-2375

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Kinsenoside Targets IDH1 to Restore Microglial Immune-Metabolic Homeostasis for Alzheimer's Disease Therapy.

Li Q, Liao Y, Zhao YB, Wu H, Jin T, Li S, Liu Y, Li P, Ouyang S, Li Z, Xia Y, Hua Q, Pan RY, Yuan Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 14;:e75125

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Inorganic Arsenic Attenuates Crystalline Silica-Induced Pulmonary Inflammation and Fibrosis by Ameliorating Autophagolysosomal Dysfunction in Alveolar Macrophages.

Luo Y, Su W, Luo Y, Han Y, Gong S, Shen F, Jin Y, Guan Y, Zhao X, Li J
Biological trace element research 2026 Apr 14;

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Inhibition of TRPC6 channel suppresses bladder cancer proliferation by disrupting store-operated calcium entry.

Zha J, Guo X, Liao W, Wu P, Wu Y, Guo Y, Yang W, Gao L
Scientific reports 2026 Apr 14;

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Increased expression of a subset of genes within reduced copy number regions across multiple cancer types.

Melhuish TA, Adair SJ, Shah A, Bauer TW, Wotton D
bioRxiv : the preprint server for biology 2026 Apr 14;

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Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus.

Guan J, Zhou D, Shao R, Liu X, Peng J, Huang Y, Qi S, Xi C, Wang M, Sun B, Qi Y, Yin X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 13;:e75255

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Beryllium Sulfate-Induced Cellular Senescence via the IL-6/STAT3 Pathway to Promote Pulmonary Fibrosis.

Lu Y, Li Y, Tong Y, Huang L, Zhang Z
Journal of applied toxicology : JAT 2026 Apr 13;

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TMEM174 Deficiency Reduces Longevity by Promoting Phosphate-Driven Vascular Calcification.

Miranda JG, Blaine J, Miyazaki M
bioRxiv : the preprint server for biology 2026 Apr 13;

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Tucatinib alleviates postmenopausal osteoporosis by suppressing osteoclast differentiation via regulating the DRP1/NFATc1/CTSK signaling pathway.

Liu X, Liu S, Xu G, Chen W, Shi Y, Wang G, Cao Y, Lu G, Ning Y, Zhao Y
Biochemical pharmacology 2026 Apr 12;250(Pt 1):117962

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Bafetinib enhances anti-tumor immunity by activating the NLRP3 inflammasome in macrophage.

Liu D, Jin X, Zeng Y, Zhou X, Wang M, Shen H, Huang Y
Autophagy 2026 Apr 12;:1-19

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Leucine catabolic enzyme AUH regulates BAT thermogenesis via PPARγ HMGylation and RNA-binding function in male mice.

Jiang H, Ni S, Li Z, Chen S, Li X, Zhang H, Shen WL, Jiang X, Luo P, Shu Y, Yuan F, Tong K, Xiao F, Guo F
Nature communications 2026 Apr 10;

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Protective effect of pentoxifylline against high-glucose-induced ferroptosis in vascular smooth muscle cells.

Zhou J, Jiao L, Jin S, Ran Y, Meng X, Bai L, Xi Y, Wang J, Zhao Z
Journal of molecular endocrinology 2026 Apr 1;76(3)

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m6A Modification of ATOX1 Inhibits Acute Myeloid Leukemia Progression by Promoting Cuproptosis.

Peng J, Fu X, Li S, Hu C, Zhao X, Peng J
Cancer research communications 2026 Apr 1;6(4):714-727

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T-2 toxin induces ER stress-dependent liver injury via mitophagy-mediated ER-phagy suppression: Berbamine blocks SNARE complex for hepatoprotection.

Xu Q, Deng L, Xu J, Wu Z, Lin R, Deng Y, Wen J
Journal of hazardous materials 2026 Apr 1;507:141693

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Recombinant tissue plasminogen activator protects neurons after intracerebral hemorrhage through activating the PI3K/AKT/mTOR pathway.

Jing J, Chen S, Wu X, Yang J, Liu X, Wang J, Wang J, Li Y, Zhang P, Tang Z
Neural regeneration research 2026 Apr 1;21(4):1574-1585

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METTL16 improves cigarette smoking-induced COPD emphysema through inhibiting autophagy by mediating pri-miR-511 m6A modification.

Cai X, Huang B, Gao F, Hu J, Yang F, Tang Y, Yu J, Tan X, Wang C, Qin H
International immunopharmacology 2026 Apr 1;174:116397

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Allicin protects against inflammation via suppression of PI3K/AKT/NF-κB signaling pathway in the model of acute cutaneous injury mouse and LPS-induced keratinocyte.

Zheng H, Tang D, An S, Fang L, Li J, Zhang Q, Kong J, Lu W, Fan Z
International immunopharmacology 2026 Apr 1;174:116331

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Ferrostatin-1 attenuates sepsis-induced lung injury by inhibiting ferroptosis via activation of the SLC7A11/GSH/GPX4 signaling pathway.

Zhang H, Li H, Liu S, Zheng J, Li P
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2026 Apr 1;1273:124962

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Expansion of outer cortical CUX2 neurons requires adaptations for DNA repair.

Xia W, Morcom L, Xu Z, Lu IL, Wang Q, Hoi KK, Wei M, Zhu K, Jordan G, Tang XY, Gonzalez-Maya J, Mattera VS, Panigrahi SM, Kawaguchi R, Emery B, Franco SJ, Geschwind DH, Popko B, Rowitch DH, Fancy SPJ
Nature 2026 Apr 1;

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GenX induces offspring vascular endothelial ferroptosis by targeting GPX4 for ubiquitination-dependent degradation.

Li J, Cui Y, Zheng C, Zhang Y, Li S, Li L
Current research in toxicology 2025;9:100260

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The suppression of the SPHK1/S1P/S1PR3 signaling pathway diminishes EGFR activation and increases the sensitivity of non-small cell lung cancer to gefitinib.

Zhang J, Wang Z, Wei X, Han M, Yan R, Ma L, Pan Y
Current research in pharmacology and drug discovery 2025;8:100212

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Proteogenomic Analysis Identifies Clinically Relevant Subgroups of Collecting Duct Carcinoma.

Qu Y, Pei X, Feng J, Yan X, Zhang L, Wang J, Yao X, Bian J, Gan Y, Gan H, Jiang X, Yang P, Cai M, Li L, Wu X, Jing W, Zhang C, Zhao J, Zhang H, Shi G, Zhou X, Ye D, Ding C
Research (Washington, D.C.) 2025;8:0859

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Combinational Analysis of Metabolomic and O-GlcNAcylation Omics Reveals the HBP Metabolic Regulation of Chemoresistance via GFPT1/NR3C1 O-GlcNAcylation/GPX4 Axis.

Zhou X, Zhang C, Li L, Feng Z, Bai X, Mei Y, He W, Gou X, Li X
Research (Washington, D.C.) 2025;8:0809

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EDEM1 Inhibits Endoplasmic Reticulum Stress to Induce Doxorubicin Resistance through Accelerating ERAD and Activating Keap1/Nrf2 Antioxidant Pathway in Triple-Negative Breast Cancer.

Wang Y, Liang Y, Luo D, Ye F, Jin Y, Wang L, Li Y, Han D, Wang Z, Chen B, Zhao W, Wang L, Yang Q
Research (Washington, D.C.) 2025;8:0797

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DDX10 Exacerbates Exosomal PD-L1-Dependent T Cell Exhaustion via Phase Separation of Rab27b in Oral Squamous Cell Carcinoma.

Li B, Cui H, Liu W, Lan Z, Liu C, Yang Y, Zhao Y, Tian Z, Chen H, Yu G
Research (Washington, D.C.) 2025;8:0697

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tRF-AspGTC Promotes Intracranial Aneurysm Formation by Controlling TRIM29-Mediated Galectin-3 Ubiquitination.

Wang C, Yu B, Zhou H, Li H, Li S, Li X, Wang W, Feng Y, Yu T
Research (Washington, D.C.) 2025;8:0574

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PCSK9/LOX-1 is associated with T2DM and regulates high glucose-induced lipid metabolism dysfunction in human microvascular endothelial cells.

Yao Y, Liu H
Endokrynologia Polska 2025;76(1):116-123

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Upstream Stimulatory Factor 2 Protects Cardiomyocytes by Regulating Mitochondrial Homeostasis.

Wu W, Zhao K, Li K, Zhu Z, Li Y, Chen J, Ding H, Zhang X
International heart journal 2025;66(2):302-312

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Effect of betaine on growth performance, methionine metabolism, and methyl transfer in broilers aged 1 to 21 days and fed a low-methionine diet.

Wang H, Liu L, He X, Bian G
The journal of poultry science 2025;62:2025010

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A single-sEV analysis identifies plasma EPCAM(+) sEVs as a biomarker for early diagnosis and monitoring postoperative remission of thyroid cancer.

Yu S, Luo Y, Dang T, Peng C, Gan Q, Liang Y, Yu J, Long P, Zhou W, Dai D
Extracellular vesicles and circulating nucleic acids 2025;6(4):982-999

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H2S inhibits high glucose-induced osteoblast injury by inhibiting ferroptosis in diabetic osteoporosis in vitro.

Shi Q, Chen F, Wu W
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2025;58:e14679

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Quercetin, a Natural Dietary Flavonoid, Emerges a Novel USP7 Inhibitor with Anti-colorectal Cancer Effects.

Li X, Li Q, Huang Y, Zhou H, Yang Q, Kong L
Biological & pharmaceutical bulletin 2025;48(10):1485-1492

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Molecular hydrogen mitigates NEMP-induced male reproductive cells apoptosis via scavenging ROS.

Ma L, Bao S, Yang X, Liu H, Xiao Y, Lin X, Cui X, Zhao Q, Wang JF, Yan H, Liu Z, Guo Y, Guo J
Electromagnetic biology and medicine 2025;44(4):405-417

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Chaperone-mediated autophagy dysfunction in imiquimod-induced psoriasiform dermatitis.

Zhao W, Liao K, Song W, Wang J, Cai C, Zhou F, Zang D, Xu D, Zhou H
Autophagy reports 2025;4(1):2544061

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SORBS1 Knockdown Resists S/G2 Arrest and Apoptosis Caused by Polyphyllin H-Induced DNA Damage in Pancreatic Cancer.

Hu X, Xue Y, Fang F, Li J, Yuan X, Cheng G, Yuan H, Zhang Y, Zhou Y, Yang S, Qiu P, Lu Y, Tang H
Oncology research 2025;33(9):2491-2506

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ERRγ Promotes Multiple Myeloma Survival by Coordinating NF-κB Signaling and Mitochondrial Apoptosis Regulation.

Zhou X, Li Y, Jing Z, Yu W, Chen J
Oncology research 2025;33(9):2399-2420

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CYMP-AS1 Promotes Ovarian Cancer Progression by Enhancing the Intracellular Translocation of hnRNPM and Reducing the Stability of AXIN2 mRNA.

Wang Y, Meng Y, Xia W, Liang Y, Wang Y, Li P, Fang L
Oncology research 2025;33(8):2141-2159

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GPX4 predicts poor prognosis and regulates tumor proliferation and senescence in colorectal adenocarcinoma.

Zhang YU, Wang Q, Han Y, Piao J, Jin X
Oncology research 2025;33(8):1933-1945

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A novel Wnt/β-catenin signaling gene signature for progression and metastasis of gastric cancer.

Chen J, Jiang F, Niu K, Zhao H, Li LI, Yu H
Oncology research 2025;33(5):1199-1215

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Investigation on the Anti-Cancer Effects of HER2-Targeted CAR-T Cells Engineered Using the PiggyBac Transposon System.

Li TT, Meng MY, Yu Z, Guo YF, Zhao YY, Gao H, Yang LL, Yang LR, Chu MY, He S, Liu Y, Wang XD, Wang WJ, Hou ZL, Liao LW, Li L
Oncology research 2025;33(11):3447-3467

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ARPC1B Promotes Clear Cell Renal Cell Carcinoma Progression via the Wnt/β-Catenin Signaling Pathway.

Peng J, Xue Y, Cai Z, Li Z, Han K, Lin X, Li Y, Zhuo Y
Oncology research 2025;33(10):3127-3154

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Deep learning identification of novel autophagic protein-protein interactions and experimental validation of Beclin 2-Ubiquilin 1 axis in triple-negative breast cancer.

Li X, Jin W, Wu L, Wang H, Xie X, Huang W, Liu BO
Oncology research 2025;33(1):67-81

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Identification of pivotal genes and crucial pathways in liver fibrosis through WGCNA analysis.

Zhang X, Yang F, Han L, Su Q, Gao Y, Wu R, Wang D, Li W, Zheng K, Liu F, Ran J
Technology and health care : official journal of the European Society for Engineering and Medicine 2025;33(1):431-448

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Hsa-miR-214-3p inhibits breast cancer cell growth and improves the tumor immune microenvironment by downregulating B7H3.

Lu Y, Wang K, Peng Y, Chen M, Zhong L, Huang L, Cheng FU, Sheng X, Yang X, Ouyang M, Calin GA, He Z
Oncology research 2025;33(1):103-121

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Study of the role of transmembrane emp24 domain-containing protein 2 in oral squamous cell carcinoma.

Zhao-Wei R, Xue-Feng J, Gao-Tian X, Jin-Ling C, Jun LI, Shu-Ying LV
Journal of applied oral science : revista FOB 2025;33:e20240305

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Integrated Metabolomics and Proteomics to Decipher Simiao Pill Improving Lipid Homeostasis through PTGES3-mediated Arachidonic Acid Metabolism in AIA Model.

Cai Y, Guo S, Lin C, Wang Y, Wang C, Wang Z, Xie D, Guan Y, Qiu S, Dong H, Zhang A
Current pharmaceutical design 2025;31(23):1885-1902

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TRIM22 functions as a scaffold protein for autophagy initiation.

Park H, Heo H, Song Y, Lee MS, Cho Y, Lee JS, Chang J, Lee S
Animal cells and systems 2025;29(1):296-311

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GYY4137 protects against type 2 diabetes mellitus-associated myocardial autophagy by suppressing FOXO1 signal pathway.

Zhu G, Li X, Gao Q, Wang Y, Li J, Huang Z, Lin Y
Animal cells and systems 2025;29(1):13-23

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Engineered Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Mitigate Liver Fibrosis by Delivering USP10 to Reprogram Macrophage Phenotype.

Tian S, Zhou X, Zheng L, Liu J, Zhang M, Ma S, Zheng X, Guo G, Ju R, Yang F, Liu Y, Li B, Hu Y, Xia E, Su R, Sun K, Cui L, Guo C, Zhou X, Wang J, Shang Y, Han Y
Biomaterials research 2025;29:0244

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Ginsenoside Rh2-Pretreated Mesenchymal Stem Cell Exosomes Ameliorate Collagen-Induced Arthritis via N6-Methyladenosine Methylation.

Zhou Z, Wu S, Li Y, Shao P, Jiang J
Biomaterials research 2025;29:0220

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Breaking the Chains of Therapeutic Blockade: Pyroptosis-Induced Photothermal-Chemotherapy with Targeted Nanoprobes in Triple-Negative Breast Cancer.

Li Z, Yu K, Cao Y, Yuan H, Wu L, Xiong L, Tang Y, Liang B
Biomaterials research 2025;29:0200

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Decellularized Extracellular Matrix Scaffold Loaded with Regulatory T Cell-Conditioned Medium Induces M2 Macrophage Polarization.

Jiang H, Sun X, Liu J, Fang L, Liang Y, Zhou J, Wu Y, Lin Z
Biomaterials research 2025;29:0196

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Multiaction Antimicrobial, Anti-inflammatory, and Prohealing Hydrogel as a Novel Strategy for Preventing Postoperative Pancreatic Fistula.

Zhou Y, Li L, Chen F, Huang T, Pan M, Huang H
Biomaterials research 2025;29:0194

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Three-Dimensional Printed Cell-Adaptable Nanocolloidal Hydrogel Induces Endogenous Osteogenesis for Bone Repair.

Lu W, Li L, Wang R, Wu Y, Chen Y, Tan B, Zhao Z, Gou M, Li Y
Biomaterials research 2025;29:0146

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PGC-1α agonist ZLN005 ameliorates OVA-induced asthma in BALB/c mice through modulating the NF-κB-p65/NLRP3 pathway.

Fang R, Cheng Y, Chen P, Hu J, Yang L
Iranian journal of basic medical sciences 2025;28(6):710-717

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Pretreatment with a ketogenic diet inhibits mitochondrial damage in rat models of spinal cord injury via the PGC-1α/Sirt1/Nrf1 pathway.

Wang X, Lan W, Liao Y, Lu H
Iranian journal of basic medical sciences 2025;28(11):1516-1522

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Role of VDAC1 in hepatocyte apoptosis during acute liver injury in rats induced by obstructive jaundice.

Liu J, Hu J, Xu H, Yan L, Yao J, Cao B
Iranian journal of basic medical sciences 2025;28(1):87-97

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Photothermal-gas combination therapy promotes checkpoint blockade immunotherapy in colon cancer.

Zheng B, Wang H, Zhai S, Li J, Lu K
Science and technology of advanced materials 2025;26(1):2504867

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Curcumin-enhanced elvitegravir therapy mitigates neuroinflammation and cognitive deficits in EcoHIV mice.

Godse S, Zhou L, Sinha N, Salman M, Ishrat T, Kumar S
Experimental biology and medicine (Maywood, N.J.) 2025;250:10758

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Tobacco carcinogen NNK promotes pancreatic cancer proliferation via LINC00857/β-catenin.

Zhou C, Cao R, Wang Q, Mo J, Qian W, Feng Z, Zhang S, Chen X, Hao J, Ma Q, Wu Z, Wang Z
Tobacco induced diseases 2025;23

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Mechanisms of Huhuang decoction in treating diabetic wounds: a network pharmacological and experimental study.

Zhang J, Shi Y, Wang J, Gao M, Zhong S, Chen Y, Hao J, Yang P, Xu S, Liu Y
International journal of medical sciences 2025;22(8):1811-1824

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Ubiquitin C-terminal hydrolase L5 promotes the development of renal cell carcinoma through the glycolysis mediated by the phosphatidylinositol-3-kinase/protein kinase B/mammalian target of rapamycin pathway.

Ruan L, Li S, Xu L
CytoJournal 2025;22:99

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Solute carrier family 6 member 3 promotes the development of clear cell renal cell carcinoma by enhancing glycolysis and inhibiting ferroptosis.

Zhao H, Ji Y, Liang C
CytoJournal 2025;22:65

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Exploring miR-3148's impact on Krüppel-like factor 6-driven mitophagy and apoptosis in myocardial ischemic injury.

Huang C, Li L, Deng H, Su J, Wei Q, He Y, Xian L
CytoJournal 2025;22:19

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Pterostilbene Induces Apoptosis in Awakening Quiescent Prostate Cancer Cells by Upregulating C/EBP-β-Mediated SOD2 Transcription.

Xi Z, Liu M, Jiang X, Feng J, Dai R, Nik Nabil WN, Sun X, Chen J, Ren H, Zhang J, Dong Q, Yuan M, Li Y, Xu H
International journal of biological sciences 2025;21(8):3379-3396

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RNF2 Modulates Lipid Metabolism and Inflammation in Alcohol-associated Liver Disease by Interacting with USP7.

Yan Q, Fang Q, Chen Z, Chen L, Du J
International journal of biological sciences 2025;21(7):3306-3323

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OLFML3 Promotes IRG1 Mitochondrial Localization and Modulates Mitochondrial Function in Macrophages.

Yu Q, Mei H, Gu Q, Zeng R, Li Y, Zhang J, Gao C, Fang H, Qu J, Liu J
International journal of biological sciences 2025;21(5):2275-2295

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Targeting ALG3/FOXD1/BNIP3 Axis Prevents Mitophagy and Gemcitabine Resistance of Nasopharyngeal Carcinoma.

Wang Z, Jin Y, He D, Zhu Y, Xiao M, Liu X, Cheng Y, Cao K
International journal of biological sciences 2025;21(5):1894-1913

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TRIM32 promotes neuronal ferroptosis by enhancing K63-linked ubiquitination and subsequent p62-selective autophagic degradation of GPX4.

Zhou X, Zhao Y, Huang S, Shu H, Zhang Y, Yang H, Ren Y, Zhou X, Liu W, Song T, Zhao J, Ma J
International journal of biological sciences 2025;21(3):1259-1274

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Tumor-associated macrophages drive heterogenetic CD10(High) cancer stem cells to implement tumor-associated neutrophils reprogramming in oral squamous cell carcinoma.

You Y, Du Z, Tian Z, Li S, Yu F, Xiao M, He Y, Wang Y
International journal of biological sciences 2025;21(3):1110-1126

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Deficiency of Epithelial PIEZO1 Alleviates Liver Steatosis Induced by High-Fat Diet in Mice.

Xu Z, Xu S, Liu X, Cheng L, Liu X, Xie X, Zhou D, Wang D, Chen J, Deng X, Zhang L, He R, Li Y, Cheng M, Yang L, Hou X, Bai T
International journal of biological sciences 2025;21(2):745-757

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Disruption of the Clock Component BMAL1 in HDM-induced Asthma Causes GC Resistance in Airway Epithelial Cells by Regulating GR Phosphorylation through the DUSP4-p38MAPK Pathway.

Huang H, Liao H, Chen Y, Hu M, Jiang X, Yu Q, Gao Y, Yang H, Zhuo J, Liu D, Huang L, Zhang J, Li Y, Du Y, Lin X, Meng X, Zou F, Zou M, Wu J, Cai S, Dong H
International journal of biological sciences 2025;21(14):6482-6500

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WTAP Maintains Alternative Activation of Macrophages by Promoting IDH1-Mediated α-ketoglutarate Production.

Xu Q, Zhang J, Zou Y, Chen L, Sun F, Luo X, Wang T, Li Y, Zhang S, Xiong F, Yu Q, Yang P, Gong Q, Liu SW, Wang CY
International journal of biological sciences 2025;21(12):5428-5443

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METTL16 Promotes Lipid Metabolic Reprogramming and Colorectal Cancer Progression.

Li J, Luo Q, Lu M, Lu C, Xu C, Ding J, Zhan T, Zhu J, Qian M, Lin S, Chang L, Li J, Wang K
International journal of biological sciences 2025;21(11):4782-4797

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Fibroblast Growth Factor 21 Protects Against Cerebral Ischemia/Reperfusion Injury by Inhibiting Oxidative Stress and Ferroptosis.

Li J, Jiang H, Bai W, Yang Y, Zhou G, Chen W, Shao J
Neuropsychiatric disease and treatment 2025;21:355-371

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Single-Cell Transcriptomic Analysis Reveals an Inflammatory Antigen-Presenting Macrophages Subtype Drive Vitiligo Pathogenesis Through STAT1-Mediated Dual Mechanisms.

Qi R, Huang M, Lin Z, Deng H, Sa R, Chen Y, Chen G, Duan X
Mediators of inflammation 2025;2025:e8878698

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Expression Profile of Urinary Exosomal miRNAs in Patients With Diabetic Kidney Disease and Their Association With Kidney Damage.

Li J, Han L, Wang T, Yang L, Zhou H
International journal of endocrinology 2025;2025:9927320

---

Gua Sha Alleviates Radiculitis-Induced Pain Via HIF-1α-Mediated Metabolic Reprogramming Pathway in Rats.

Ge H, Yan S, Yin M, Gao Y, Wang J, Wang Q, Xu G, Yang M
Pain research & management 2025;2025:9923147

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ECM Protein CYR61 Promotes Migration and Osteoblastic Differentiation of Irradiation BMSCs via Migrasomes.

Yan C, Sun W, Chen Z, Liu L, Zhou P, Gu Y, Wu G, Wang K
Stem cells international 2025;2025:8825935

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Gut Microbiota-Derived Butyric Acid Alleviates Glucocorticoid-Associated Osteonecrosis of the Femoral Head via Modulating Inflammatory Cytokines in Bone Marrow Mesenchymal Stem Cells.

He S, Chen H, Xi H, Sun G, Du B, Liu X
Mediators of inflammation 2025;2025:8742817

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The Dynamic Expression Changes of Neutrophil Extracellular Traps in Mouse Apical Periodontitis: A Potential Correlation With IL-17.

Ma Z, Sun X, Lin Y, Wang Z, Nie Q, Yu J, Yang J, Zhu L
Journal of immunology research 2025;2025:8039031

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Human Umbilical Cord Mesenchymal Stem Cells Inhibit the Progression of Osteoarthritis by Suppressing NLRP3-Mediated Synovial Inflammation in the Early Stages of the Disease.

Li Y, Ouyang Y, Lang R, He J, Zheng S, Ao C, Jiang Y, Xiao H, Li M, Li C, Wu D
Stem cells international 2025;2025:7558817

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MicroRNA-429 Inhibits Microglial Inflammation by Targeting IKKβ Through the NF-κB Pathway.

Ke Z, Chen Y, Lin X, Jiang J
Mediators of inflammation 2025;2025:7165782

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RPL39 Was Associated With Sex Differences in Pulmonary Arterial Hypertension.

Wang H, Li L, Zhou G, Wang L, Wu Z
Canadian respiratory journal 2025;2025:7139235

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Umbilical Cord Mesenchymal Stem Cells Attenuate Podocyte Injury in Diabetic Nephropathy Rats by Inhibiting Angpltl4/Integrin β3 in the Glomerulus.

Liu S, Meng M, Huang C, He L, Wang P, Tang Z, Ran X, Gao H, Guo Y, He Y, Chen J, Hu H, He S, Zhao Y, Hou Z, Li L, Li W, Wang W, Wang X
Journal of diabetes research 2025;2025:6683126

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Comparative Pathogenicity of PCV2, PCV3, and PCV4 in Piglets: Insights Into Clinical, Pathological, and Immunological Features.

Zheng J, Li X, Lv X, Han Y, Zhang X, Chen S, Zhang F, Ren L
Transboundary and emerging diseases 2025;2025:6362100

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FTO Alleviates Hepatic Ischemia-Reperfusion Injury by Regulating Apoptosis and Autophagy.

Wang PX, Zhu L, Xiang M, Zhang R, Zheng X, Zheng Z, Li K
Gastroenterology research and practice 2025;2025:5587859

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Comparison and Analysis of the Drug-Resistance Mechanism of Osimertinib- and Almonertinib-Resistant Cell Lines.

Zheng C, Ren Y, Wang K, Chen X, Tao J, Zhang C, Liu Z, Sun L, Zhai L
Analytical cellular pathology (Amsterdam) 2025;2025:5578693

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Molecular Characterization and Pathogenicity of a Novel Recombinant NADC30-Like PRRSV Strain Isolated From Piglets Inducing Intestinal Inflammation, and Construction of Its Infectious Clone.

Lin Y, Ouyang Y, Zheng J, Xiao C, Yang Y, Zhao Q, Zhang Y, Li Z, Liu K, Li B, Shao D, Qiu Y, Ma Z, Wei J
Transboundary and emerging diseases 2025;2025:4893251

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Mechanism of Curcumin in Inhibiting Proliferation of Head and Neck Squamous Cell Carcinoma: A Network Pharmacology and Cellular Experimental Study.

He Y, Liao Y, Fang S, Zhu L, Zhao Z, Chen T, Zhang Z
BioMed research international 2025;2025:4318115

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Foxj2 Attenuates LPS-Induced Inflammatory Response in Macrophages.

Huang P, Fu J, Hu J, Lei Y, Dai C, Wu T, Liu J
Mediators of inflammation 2025;2025:3854538

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Single-Cell Transcriptomics Uncover EEF1A1-Driven Ubiquitination Dysregulation in T Cell Exhaustion and SLE Pathogenesis via STAT1-Mediated Th1/Th2 Imbalance.

Xing L, Wu T, Xu H, Yang S, Luan C, Xu Y, Mao Y, Li X
Mediators of inflammation 2025;2025:3708640

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G Protein-Coupled Receptor 30 Attenuates Neuronal Pyroptosis Induced by Subarachnoid Hemorrhage.

Peng J, Hu X, He J, Xia Y
Mediators of inflammation 2025;2025:3585885

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Pseudorabies Virus UL41 Hijacks IFN Response via JAK/STAT Pathway While Cellular TRIM21 Blocks it Through K48 Ubiquitination.

Li X, Zheng J, Zhang G, Li P, Dong M, Liu Q, Ren L
Transboundary and emerging diseases 2025;2025:3468674

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HMGB1 Exacerbates Intestinal Barrier Damage by Inducing Ferroptosis Through the TLR4/NF-κB/GPX4 Pathway in Ulcerative Colitis.

Zhu N, Ge X, Zhang L, Chen X, Xiang W, Mei Q
Mediators of inflammation 2025;2025:2395557

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Vimentin Regulates Alternative Polyadenylation and mTOR Signaling via ARVCF to Promote B Cell Lymphoma Progression.

Shao L, Xing Q, Xiong Y, Jin K, Li Q, Dong C, Ye Q
Human mutation 2025;2025:1463685

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Integrating network pharmacology and experimental verification to explore the protective effects of Evodia rutaecarpa in ischemic stroke.

Huang Z, Liu J, Li H, Huang H, Ai Y, Zhou D
PloS one 2025;20(6):e0327133

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Downregulation of OIP5-AS1 inhibits apoptosis in myocardial ischemia/reperfusion injury via modulating the MiR-145-5p/ROCK1 axis.

Yang J, Liu J, Liu X, Xu D, Zhang J
PloS one 2025;20(5):e0324909

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Inhibition of HPSE/SDC-2 axis-induced epithelial-mesenchymal transition for treating IC/BPS.

Chen Z, He Y, Zhang J, Ge Q, Du T, Fan Z, Zhou J, Yang X, Shen B, Wei Z
PloS one 2025;20(5):e0321730

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Voluntarily wheel running protects doxorubicin-induced kidney injury by inhibiting oxidative stress through mitochondrial function.

Jiang X, Wang Z, Wang L, Wang Y, Zhao L, Jiang H
PloS one 2025;20(4):e0321121

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Meriones unguiculatus serves as a spontaneous primary aldosteronism rodent model.

You M, Lu Z, Wang B, Liu M, Zhou Q, Li L, Tong D, Zhao Y, Zhang H, Bai Z, Wang L, Cao T, Gao P, Yan Z, Zhu Z
PloS one 2025;20(2):e0314943

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Xiao Qing Long Tang ameliorates neutrophil extracellular trap-dendritic cells-T helper 17 cell axis in Neutrophilic Asthma.

Ji X, Chen H, He SD, Huang M, You X, Xiao C, Chen Z, Cai J
PloS one 2025;20(11):e0336333

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PIM1 induces hypoxia-related fibroblast senescence in a mouse model of stress urinary incontinence.

Xiao Y, Chen M, Li L, Chen L, Tian X, Huang X, Zhu F, Li B, Hong L
PloS one 2025;20(11):e0335501

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Scutellarin combined with lidocaine exerts antineoplastic effect in human glioma associated with repression of epidermal growth factor receptor signaling.

He XY, Yang YS, Zheng YX, Xia QJ, Yu HZ, Zhao XM, Wang TH
PloS one 2025;20(1):e0318031

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Antioxidative and anticancer effects of Tacca chantrieri extract enhancing cisplatin sensitivity in cholangiocarcinoma cells.

Armartmuntree N, Kittirat Y, Promraksa B, Loilome W, Dokduang H, Techasen A, Sansomchai P, Thanee M, O'Connor T, Kongthitilerd P, Padthaisong S
PloS one 2025;20(1):e0317111

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Nitroxyl protects H9C2 cells from H/R-induced damage and inhibits autophagy via PI3K/Akt/mTOR pathway.

Li L, Wang Z, Lyu Y, Guo Y
PloS one 2025;20(1):e0314500

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Integrating experimental and network pharmacology to explore the pharmacological mechanisms of Dioscin against glioblastoma.

Huang J, Jiang C, Li T, Hu Z, Xiang Q, Chen H
Open medicine (Warsaw, Poland) 2025;20(1):20251194

---

Necroptosis of hippocampal neurons in paclitaxel chemotherapy-induced cognitive impairment mediates microglial activation via TLR4/MyD88 signaling pathway.

Liu LL, Liu X, Zhao S, Li Z, Liu JX, Ma DY, Wang XL
Open medicine (Warsaw, Poland) 2025;20(1):20251182

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AKAP12, mediated by transcription factor 21, inhibits cell proliferation, metastasis, and glycolysis in lung squamous cell carcinoma.

Chen J, Liao H, Wang K, Yan T, Ma S, Bai G
Open life sciences 2025;20(1):20220912

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Copper-Based Metal-Organic Framework Nanoplatform for miRNA Delivery: Synergistic Antitumor Therapy.

Tu M, Deng X, Lai B, Liu J, Tao Y, Xu S, Li X, Niu X, Li Z, Huang J, Li J, Mao S, Ouyang X, Cao J
International journal of nanomedicine 2025;20:8675-8692

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Yttrium Oxide Nanoparticles Affect Both Cognitive and Memory Function by Disrupting Copper Output in Neuronal Cells in a Rat Model.

Zheng M, Chen Z, Xie J, Yang Q, Mo M, Chen L
International journal of nanomedicine 2025;20:5799-5815

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Polyallylamine Hydrochloride-Modified Bovine Serum Albumin Nanoparticles Loaded with α-Solanine for Chemotherapy of Pancreatic Cancer.

Wen Z, Luo S, Liu J, Huang Y, Chen G, Cai H
International journal of nanomedicine 2025;20:4235-4255

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Hypericin Nanoparticles-Associated Photodynamic Therapy Modulates the Biological Behavior of Hepatocellular Carcinoma by SERPINE1.

Yan X, Fan J, Qin W, Liao M, Li S, Suo L, Xie Y, Jiang X, Zou D, Liao W
International journal of nanomedicine 2025;20:3713-3730

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MOF-Mediated Aloe-Emodin Delivery Enhances Hepatocellular Carcinoma Immunotherapy via Pyroptosis and Immunosuppressant Synergy.

Xie H, Yi X, Huang K, Luo J, Zeng Q, He F, Wang L
International journal of nanomedicine 2025;20:11647-11667

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Suppression of Hepatocellular Carcinoma by Deletion of SIRT2 in Hepatocytes via Elevated C/EBPβ/GADD45γ.

Wang F, Keating CR, Xu Y, Hou W, Malnassy G, Boedeker K, Perera A, Ham E, Patel D, Ding X, Qiu W
Cellular and molecular gastroenterology and hepatology 2025;19(7):101494

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Modified Sijunzi Decoction Inhibits Pancreatic Cancer Progression and Improves Immune Suppression: Network Pharmacology and Experimental Validation.

Zhang Y, Ruan L, Li X, Si W, Yang P, Ba H, Chen Z
Drug design, development and therapy 2025;19:8949-8966

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Liu Wei Di Huang Decoction Alleviates Renal Fibrosis by Inhibiting Endothelial Mesenchymal Transitions via Upregulating Sirt1 Expression and Inhibiting the Wnt/β-Catenin Signaling Pathway.

Wang H, Chen SS, Zhang YX, Gao HB, Meng B, Wu WY, Tang Q
Drug design, development and therapy 2025;19:6587-6603

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Artesunate Mitigates Sepsis-Induced Acute Kidney Injury via Lactate/AMPK/mTOR-Regulated Autophagy Based on Multi-Omics.

Chen H, Du P, Guo R, Li X, Zhang L, Duan J, Chen M, Guo J, Li Y, Jiang T
Drug design, development and therapy 2025;19:5911-5928

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The Effective Compound Combination of Bufei Yishen Formula III Improves the Mitochondrial Dysfunction via Inhibiting JNK/Sab Pathway in COPD Mice.

Song M, Han M, Zhang H, Yang Y, Tian Y, Li J, Zhao J
Drug design, development and therapy 2025;19:525-538

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Olive Oil Solution of Volatile Oil from Citri Reticulatae Pericarpium Viride Alleviates Slow-Transit Constipation via Regulating SCF/c-Kit Signaling Pathway and Intestinal Flora.

Zou S, Xie B, An Z, Li F, Cui L, Zhang Z, Bu W, He D
Drug design, development and therapy 2025;19:4275-4295

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ShenQi ShenKang Granule Alleviates Chronic Kidney Disease by Inhibiting the PI3K/AKT/mTOR Pathway and Restoring Autophagy Flux and Mitochondrial Integrity.

Xia C, Zhang J, Chen H, Zhou S, Jiang W, Zheng H, Lin Z, Tan Q, Sun W
Drug design, development and therapy 2025;19:3925-3947

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Huanglian Ejiao Decoction Alleviates Ulcerative Colitis in Mice Through Regulating the Gut Microbiota and Inhibiting the Ratio of Th1 and Th2 Cells.

Tang J, Hu Y, Fang J, Zhu W, Xu W, Yu D, Zheng Z, Zhou Q, Fu H, Zhang W
Drug design, development and therapy 2025;19:303-324

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Network Pharmacology, Molecular Docking, and in vitro Experiments Reveal the Role and Mechanism of Tanshinone IIA in Colorectal Cancer Treatment Through the PI3K/AKT Pathway.

Sun J, Qi X, Yang C, Wang S, Jiang J, Wang L, Song J, Yu B, Sun M
Drug design, development and therapy 2025;19:2959-2977

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HDAC7 knockout mitigates astrocyte reactivity and neuroinflammation via the IRF3/cGAS/STING signaling pathway.

Yue RZ, Guo X, Li W, Li C, Shan L
Frontiers in cellular neuroscience 2025;19:1683595

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Revealing cerebrospinal fluid biomarkers in Parkinson's disease dementia based on iTRAQ proteomics research.

Han L, Liu Y, Tan C, Mo L, Su H, Ma P, Zeng G, Yue J, Liu X, Chen L
Frontiers in neuroscience 2025;19:1682274

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ATF3 Knockdown Exacerbates Astrocyte Activation by Inhibiting Phosphorylation of Drp1 in Ischemic Stroke.

Huang R, Huang X, Yang H, Wu H, Liu F, Saw PE, Cao M
Biologics : targets & therapy 2025;19:15-29

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WD40 Protein NLE1 as a Novel Diagnostic Biomarker Promoting Hepatocellular Carcinoma Proliferation.

Zhang R, Liu D, Feng X, Yang Z, Zhang K
Clinical Medicine Insights. Oncology 2025;19:11795549251348902

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Irisin Mitigates Doxorubicin-Induced Cardiotoxicity by Reducing Oxidative Stress and Inflammation via Modulation of the PERK-eIF2α-ATF4 Pathway.

Zhang Z, Yu X, Li J, Shen X, Fu W, Liu Y, Dong X, Wang Z
Drug design, development and therapy 2025;19:1067-1081

---

Myosin 1b Inhibits the Phenotype of HemECs to Affect the Progression of Infantile Hemangiomas.

Li N, Gong X, Cao Z, Li Z, Wang L, Huo R, Fu C
Clinical, cosmetic and investigational dermatology 2025;18:989-998

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Reduced Thioredoxin Regulates IL-1β Secretion via NLRP3 of IL-1β+ Alveolar Macrophages in COPD.

Wang L, Shi R, Li Z, Ma R, Wang C, Xu C, Guo R, Xiao C, Du X, Yang W
Journal of inflammation research 2025;18:8563-8578

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Exploring the Kidney-Brain Crosstalk: Biomarkers for Early Detection of Kidney Injury-Related Alzheimer's Disease.

Cai Y, Huang G, Ren M, Chai Y, Fu Y, Yan T, Zhu L
Journal of inflammation research 2025;18:827-846

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Exploration and Validation of Key Genes and Immune Infiltration in Alcoholic Hepatitis.

Mei Y, Zheng Y, Zhang X, Hu T, Zheng X, Zhang C, Deng Q
Journal of inflammation research 2025;18:8243-8262

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Integration of Multi-Omics and Network Pharmacology Analysis Reveals the Mechanism of Qingchang Huashi Jianpi Bushen Formula in Repairing the Epithelial Barrier of Ulcerative Colitis.

Fang Y, Min S, Wu Y, Xu F, Chen H, Li Y, Lu Y, Hu J, Zhu L, Shen H
Journal of inflammation research 2025;18:6167-6189

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Taxus chinensis-Derived Nanovesicles Alleviate Mouse Colitis by Inhibiting Inflammatory Cytokines and Restoring Gut Microbiota.

Gong Q, Hu J, Pu C, Zhao Z, Guo Y
Journal of inflammation research 2025;18:5611-5625

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Exploring the Mechanism of Qinzhuliangxue Mixture for Treating Skin Lesions in Atopic Dermatitis: Insights from Network Pharmacology and Experimental Validation.

Qiao Y, Yin H, Zhang H, He Q, Li Y, Sun L, Wang J, Li X, Koh WX, Pottakorn A, Chu Z, Xiang Y
Journal of inflammation research 2025;18:5173-5187

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Systematic Analysis of E3 Ligase-Related Genes Identified UBE2L3 as a Prognostic Biomarker Associated With Drug Resistance in Acute Myeloid Leukemia.

Ling C, Cao N, Wang H, Wan Y, Liang X, Guo J, Xiao M, Zhang Q, Zhai Z
International journal of general medicine 2025;18:459-472

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Exploring The Role of TOP2A in the Intersection of Pathogenic Mechanisms Between Rheumatoid Arthritis and Idiopathic Pulmonary Fibrosis Based on Bioinformatics.

Shi S, Hong X, Zhang Y, Chen S, Huang X, Zheng G, Hu B, Lu M, Li W, Zhong Y, Sun G, Ouyang Y
Journal of inflammation research 2025;18:3449-3468

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Electroacupuncture Improves Learning and Memory Impairment in Rats with Cerebral Ischemia/Reperfusion Injury by Promoting Microglia/Macrophage M2 Polarization Through Nrf2/HO-1 Pathway.

Xiao Y, Bai Y, Sun K, Wan J, Chen L, Chen S, Wang Y, Li W, Liu A
Journal of inflammation research 2025;18:2925-2941

---

Establishment and Evaluation of HepG2 Cell Insulin Resistance Model.

Meng Z, Han Y, Ruan L, Xu C, Zhang M, Liu H
Diabetes, metabolic syndrome and obesity : targets and therapy 2025;18:2573-2584

---

Fu-Fang-Qi-Di-Hua-Yu-Tang Improves Diabetic Macrovascular Disease via PI3K/AKT Pathway Regulation.

Zhang S, Yan M, Liang P, Zhang Y, Liu J, Huang H, Li G, Wu H
Diabetes, metabolic syndrome and obesity : targets and therapy 2025;18:2247-2265

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PEDF Overexpression Ameliorates Cardiac Lipotoxicity in Diabetic Cardiomyopathy via Regulation of Energy Metabolism.

Mao T, Wang Y
Diabetes, metabolic syndrome and obesity : targets and therapy 2025;18:217-231

---

Sigma-1 Receptor Rescues Autophagy Through AMPK/mTOR Signaling Pathway in Sepsis-Induced Acute Kidney Injury.

Jiang W, Zhang J, Zhang Y, Huang Z
International journal of general medicine 2025;18:1917-1931

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Serum Exosomes miR-122-5P Induces Hepatic and Renal Injury in Septic Rats by Regulating TAK1/SIRT1 Pathway.

Wang J, Jiang Y, Yuan Y, Ma X, Li T, Lv Y, Zhang J, Chen L, Zhou J, Meng Y, Zhang B, Dong X, Ma L
Infection and drug resistance 2025;18:185-197

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STK11 Alleviates Pulmonary Inflammation During Acute Lung Injury by Phosphorylating AMPK to Activate Autophagy in A549 Cell Model.

Xiao R, Qi Z, Chen T, Wei F
Journal of inflammation research 2025;18:17789-17802

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Kushe Tincture Ameliorates DNCB-Induced Atopic Dermatitis by Affecting NF-Kb/JAK-STAT3 Pathway: Bioinformatics Analysis and Animal Experiment Verification.

Feng H, Zhou Y, Ren X, Zhu X, Duan X, Qu S, Zhu B, Li Y, Qin Y
Journal of inflammation research 2025;18:15293-15308

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Semaphorin 6D Alleviates Osteoarthritis by Inhibiting NLRP3 Inflammasome Activation and Endoplasmic Reticulum Stress.

Zhang W, Li C, Yao J, Xu Z, Huang Y, Lu Y, Lin X, Guo Z, Zhou X
Journal of inflammation research 2025;18:13909-13924

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Lactate Ameliorates Kainic Acid-Induced Neuroinflammation and Cognitive Impairment via the Chemokine Signaling Pathway in Mice.

Chu X, Ge Y, Geng C, Cao P, Wei P, Fu B, Deng Z, Li Y, Zhao G
Journal of inflammation research 2025;18:1235-1254

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Electroacupuncture Regulates Oxidative Stress-Mediated NLRP3/ASC/Caspase-1 Pathway to Inhibit Microglial Activation: Alleviating Neuroinflammation and Depression in IBD.

Li Z, Cao S, Yang J, Chen L, Jia L, Lu P, Liu J, Liu M, Liu Q
Journal of inflammation research 2025;18:11935-11950

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CKS2 Mediates Hepatocellular Carcinoma Recurrence After Hepatic Ischemia-Reperfusion Injury Related to M2 Macrophages.

Xia S, Qin X, Pan C, Fan D, Yang D
Journal of inflammation research 2025;18:11801-11819

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ALDH2 Ameliorates Acute Gouty Arthritis Through Inhibiting NLRP3 Inflammasome and Pyroptosis by Nrf2/ROS Pathway.

Tong S, Li X, Wang F, Cheng Q, Zhang P, Chen M, Xie Y, Lu X, Wu H
Journal of inflammation research 2025;18:11095-11108

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Knockdown of Long Noncoding RNA IPCRL1 Mitigates Myocardial Ischemia/Reperfusion Injury via miR-185-3p/JIP3 Axis and JNK Pathway.

Chen J, Zhang Y, Zhang Z, Yu Z, Zhang H, Zhao Q
Journal of inflammation research 2025;18:10695-10709

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Medical Hemorrhoid Gel Ameliorates Croton Oil-Induced Hemorrhoids by Suppressing the NLRP3 Inflammasome Activation via NF-κB Signaling Pathway.

Ai Z, Yuan D, Li Y, Cai J, Zhou D, Liu W
Journal of inflammation research 2025;18:10619-10636

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Study of NOX4/ROS/NF-κB signaling pathway in anti-ischemia-reperfusion injury effect and mechanism of STQJD.

Luo C, Zhang L, Wang A, Wang Y, Cai J, Ni R, Yang R, He S, Gu L, Chen P
American journal of translational research 2025;17(7):4894-4911

---

ITGA5 promotes cervical cancer progression by regulating IMP3 recruitment of HK2 mRNA.

Zhou L, Liu Y, Zhang Y, Hu F, Shen L, Hou S
American journal of translational research 2025;17(4):3031-3049

---

Hypermethylation of miR-129-2-3p inhibits esophageal cancer proliferation and migration by down-regulating PPP6C expression.

Tu A, Wu H, Wang J, Hou X, Wang M, Jiang M, Zhou X
American journal of translational research 2025;17(2):1459-1469

---

Sea buckthorn flavonoids attenuate oxidative stress in hepatocellular carcinoma via suppression of PI3K/Akt and JAK pathways.

Zhang H, Huang H, Miao F, Nan J
American journal of translational research 2025;17(12):9830-9845

---

Erianin inhibits endometrial cancer cell proliferation and migration by modulating glutamine metabolism through the ERK signaling pathway.

Huang Q, Xu Y, Li H, Zhang T
American journal of translational research 2025;17(11):8964-8972

---

PLXND1 from the Plexins family is a prognostic factor promoting colon cancer invasion and metastasis.

Chen W, Guo L, Wang Z, Wang Z, Dai X
American journal of translational research 2025;17(10):8243-8264

---

The Role of Ferroptosis in Adenoid Hypertrophy in Children with Obstructive Sleep Apnea Syndrome.

Shen Z, Huang J, Chu Y, Zhang X, Xu H, Xu H, Guan J, Gu M
Nature and science of sleep 2025;17:3167-3180

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Astrocytic Ror2-induced imbalance in brain and gut homeostasis contributes to chronic post-thoracotomy pain.

Liu C, Shen L, Xu L, Zhu A, Huang Y
Frontiers in aging neuroscience 2025;17:1675725

---

Serine-129 phosphorylated α-synuclein drives mitochondrial dysfunction and calcium dysregulation in Parkinson's disease model.

Jiao J, Liu W, Gao G, Yang H
Frontiers in aging neuroscience 2025;17:1538166

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Periplocin Targets HDAC10 to Inhibit NF-κB Signaling and Induce Apoptosis in Myeloid Leukemia Cells.

Li W, Lai S, Chen J, Chen Z, Zhou Y, Wei R, Chen Y
Journal of Cancer 2025;16(9):2970-2983

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Identification and Validation of Prognostic Genes Related to Histone Lactylation Modification in Glioblastoma: An Integrated Analysis of Transcriptome and Single-cell RNA Sequencing.

He W, Chen R, Chen G, Zhang L, Qian Y, Zhou J, Peng J, Wong VKW, Jiang Y
Journal of Cancer 2025;16(7):2145-2166

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EIF4A3 Promotes Cell Proliferation via CDC5L Upregulation in Human Breast Cancer Cells.

Zhang M, Xie Y, Song S, Wang R, Chen H, Li Y, Liu J, Li J, Jiang Y, Liu P, Wang B
Journal of Cancer 2025;16(6):1958-1970

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Mitoxantrone-liposome Sensitizes FLT3-ITD Acute Myeloid Leukemia to Gilteritinib Treatment.

Yuan S, Zhou Y, Li Y, Chen Z, Xiao W, Jiang D, Zhang P, Zhang Y, Bai F, Deng J, Lou S
Journal of Cancer 2025;16(6):1905-1917

---

ADAM10 is a key player in the diagnosis, prognosis and metastasis of non-small cell lung cancer (NSCLC).

Zhang W, Yang L, Li M, Zhang L, Cheng J, El-Far AH, Xu Y, Fu J
Journal of Cancer 2025;16(5):1736-1746

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A novel EMT-related risk score model for Uveal melanoma based on ZNF667-AS1 and AP005121.1.

Yang F, Ren Y, Qi D, Liu X, Xie J
Journal of Cancer 2025;16(2):460-469

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TYMS Enhances Colorectal Cell Antioxidant Capacity Via the KEAP1-NRF2 Pathway to Resist Ferroptosis.

Chen J, Wu W, Wang L, Zhang J, Che X, Zhai L, Zhao Z, Li Y
Journal of Cancer 2025;16(2):417-429

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Hypoxia upregulate TPM4 expression to strengthen epithelial-mesenchymal transition that promotes lymph node metastasis of papillary thyroid cancer.

Li Z, Li F, Jiang X, Li Y, Jia L, Wang X, Liu Y, Jiang R, Zhao K, Pu G, Tian Y, Wang Y, He X
Journal of Cancer 2025;16(10):3216-3234

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Dysregulation of the microbiota-gut-brain axis induced by chronic pancreatitis mediates anxiety- and depression-like behaviors in mice.

Liu L, Zhang X, Wang C, Zhou K, Bao J, Cheng Z, Sun H, Zhu C, Yu G, Xiao W, Wan R
Frontiers in immunology 2025;16:1753424

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Unveiling tumor senescence-driven prognostic heterogeneity via MALISS in stage II/III colorectal cancer.

Liu X, Liu B, Tong Y, Zhu X, Sang Y, Gao F, Niu X, Tang Y, Xu K, Chen H, Chong W, Li L
Frontiers in immunology 2025;16:1744719

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Deciphering immune cell interaction aberrations in necrotizing enterocolitis: the regulatory role of DHRS7.

Gao K, Chen Y, Lu J, Ge W, Yin Q
Frontiers in immunology 2025;16:1743878

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Integrating cuproptosis- and ferroptosis-related gene signatures to predict prognosis, immunotherapy response, and drug sensitivity in patients with skin cutaneous melanoma.

Dong H, Huang Y, Shen J, Ding Z, Wang W, Li Y
Frontiers in immunology 2025;16:1742614

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From multi-omics to functional validation: the PTMRS stratifies TME and positions PDGFRB in CRC biology.

Liu Y, Lu C, Hua L, Hao H, Zhang Q, Zou Z, Xiang J, Wang Y
Frontiers in immunology 2025;16:1728291

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Characterization and anti-inflammatory studies of supramolecular assemblies of chlorogenic acids with metal ions.

Zhang ZM, Zhang RY, Zhu L, Liu ZX, Deng HX, Tang JF, Zhang JY, Cai W
Frontiers in pharmacology 2025;16:1726226

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Berberine-taxifolin co-administration attenuates inflammatory response and intestinal barrier injury via nf-κB/NLRP3 suppression in colitis.

Miao G, Zhang D, Sui Z, Leng J, Deng Y, Gu X, Cao H
Frontiers in immunology 2025;16:1725084

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Administration of 2-deoxy-D-glucose induces pyroptosis in murine breast cancer cells via cAMP/PKA/HK2 to impair tumor survival.

Pan T, Jin S, Gao W, Eom K, Dong J, Li L
Frontiers in immunology 2025;16:1724476

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Single-cell and machine learning integration reveals OS-driven CCND1 promotes an aggressive phenotype in papillary thyroid carcinoma.

Wang J, Zhu Q, Bie J, Han Y, Liu H, Chen C
Frontiers in immunology 2025;16:1722524

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Fusobacterium nucleatum drives CD40-mediated dendritic cell activation and Th17/Treg imbalance to exacerbate intestinal inflammation in Crohn's disease.

Wang M, Sun J, Yu J, Wang J, Xu C, Ma J, Zhang H
Frontiers in immunology 2025;16:1712971

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GDF15 orchestrates mitochondrial-immune crosstalk via SMAD7-HIF-1α-PKM2 cascade to attenuate septic liver injury.

Kuang X, Niu Z, Liu W, Huang Z, Li S, Zhang Y, Wang L, Cai X, Wang F, Zhang P
Frontiers in immunology 2025;16:1712741

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m6A epigenetic signature in necrotizing enterocolitis: insights from murine to neonatal studies.

Chen Y, Wei Q, Gan Y, Wei B, Huang Q, Pan S, Chen Y
Frontiers in immunology 2025;16:1709677

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Efferocytosis-associated genes serve as prognostic biomarkers for pancreatic ductal adenocarcinoma and identify P2RY6 as a therapeutic target.

Wang X, Wang W, Yang C, Wang P, Liu Y, Yu L, Zhang S, Yan X, Wang J
Frontiers in immunology 2025;16:1708441

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IL-18 receptor axis in allergic conjunctivitis: a multi-omics study.

Yuan L, Su W, Li L, Xiang Y, Xu Z, Wang Y, Hua X, Yuan X
Frontiers in immunology 2025;16:1704591

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RPL41 inhibits the proliferation and migration of retinoblastoma through the ARL5B-associated lysosomal trafficking.

Li Y, Zhan T, Chen T, Zhong Q, Xiao S, Wang A, Jiao Y
Frontiers in immunology 2025;16:1704080

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Association of genetically instrumented HMGCR inhibition with the therapeutic role of prostate cancer: a Mendelian randomization study and supporting in vitro experiments.

Hao X, Mu J
Frontiers in pharmacology 2025;16:1701869

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Revealing the role of regulatory microglial IRF7-NLRP3 interactions in optic nerve damage of normal-tension glaucoma based on single-cell RNA sequencing.

Qiu L, Guo F, Liu X, Zhang D, Wang Q, Du M, Yuan Q, Zhang S, Song W, Yuan H
Frontiers in immunology 2025;16:1700998

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SLC16A3 drives lung adenocarcinoma progression and gefitinib resistance through coordinated regulation of ferroptosis and lactate metabolism.

Cai W, Liu Y, Zhao K, Zhu Z, Jin J, Wen J, Xue Z
Frontiers in immunology 2025;16:1699540

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Identification and functional analysis of a novel CSNK2A1 frameshift variant in stillbirth.

Zhang N, Han M, Zhao T, Tang X, Wang Z, Du Y, Wang L
Frontiers in genetics 2025;16:1692704

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Transcriptome analysis of differences in the infection of African swine fever virus (SY-1 strain) in iPAMs and PAMs.

Mao H, Cheng C, Wang Y, Zhou W, Zhang K, Wang Y, Wang L, Song Z, Sun X, Zhang Y, Hu X, Zhang Y, Zou Z, Zhao Y, Zhang Q, Jin M
Frontiers in immunology 2025;16:1692373

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RARS1 inhibits ENO1 ubiquitination and degradation to protect against ferroptosis in hepatocellular carcinoma.

Zang S, Ma J, Chen L, Cui D, Yu J
Frontiers in immunology 2025;16:1686597

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METTL3-driven m(6)A modification orchestrates mitophagy-dependent ferroptosis in PM2.5-induced lung injury.

Ran Q, Gao J, Li G, Wang J, Li X, Xiong A, Zhang Y, Xiong Y, He X
Frontiers in immunology 2025;16:1683819

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Mechanistic study on electroacupuncture-regulated circadian autophagy for inhibiting ferroptosis in hippocampal neurons and alleviating depression-like behaviors in adulthood induced by early chronic sleep deprivation.

Wu Y, Chen X, Liu F, Feng Y, Liao Z, Bu X, Fu W, Gao J, Wu L, Fan L, Yang Q, Yue P, Wang M
Frontiers in neurology 2025;16:1680606

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SCPEP1(+) basal cells are associated with the remodeling of oxidative stress signaling networks in idiopathic pulmonary fibrosis.

Zhou X, Lu T, Xu R, Wang C, Chen S, Chen J, Chang X, Li M, Shi J, Xu C, Zhao Y, Peng B, Zhao J, Zhang L
Frontiers in immunology 2025;16:1676086

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Computational-experimental strategy identifies Co-upregulated biomarkers linking coronary heart disease and type 2 diabetes pathogenesis.

Li W, Cao Y, Yu C, Che B, He M, Li D, Jiang L, Ma L
Frontiers in genetics 2025;16:1673303

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Mitophagy-associated biomarkers and macrophage involvement in pulmonary arterial hypertension: identification and functional implications.

Zhang X, Cheng L, Xie J, Ma X, Gui W, Chen J, Liu K, Ma R
Frontiers in physiology 2025;16:1673181

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Multi-omics dissection of fatty acid metabolism heterogeneity identifies PRDX1 as a prognostic marker in bladder cancer.

Wang L, Chang Z, Chen SY, Yang JW, Wang KY, Li KP, Wan S, Liu SH, Yang L
Frontiers in immunology 2025;16:1669822

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Zinc alleviates stroke development through autophagy-mediated modulation of immune microenvironment.

Qiu Z, Liu X, Li J, Yin H, Luo J, Lin Z, Rexiati M, Abulaiti A, Yasen A, Xing L, Aili D, Meng B, Li X, You Z, He J, Huang C, Qian Z, Chen J
Frontiers in immunology 2025;16:1666225

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Integrated multi-omics analysis reveals a glycolytic signature that predicts pan-cancer immune checkpoint inhibitor response and LDHA as a combinatorial target in fumarate hydratase-deficient renal cell carcinoma.

Liu S, Yuan Y, He J, Zhou Y, Wang Y, Ye X, Wang J, Zhang J
Frontiers in immunology 2025;16:1666121

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Cangfu Daotan decoction treats PCOS-IR through the IL6/JAK2/STAT3/FOXO4 signaling pathway.

Ju W, Zhang Q, Wang Y, Pan K, Li Y, Zhao S, Lian F
Frontiers in endocrinology 2025;16:1661000

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Quercetin ameliorates renal injury in hyperuricemic rats via modulating ER stress pathways.

Liu H, Yang Q, Wang S, Wang T, Pan L, Wang X, Chi Y, Jin Z
Frontiers in pharmacology 2025;16:1660599

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CRTC1 enhances PD-L1-mediated tumor immunosuppression in non-small cell lung cancer via the Notch1/Akt signaling pathway.

Feng X, Shi Y, Yuan F, Hu Y, Tang X, Zhang W, Gan J, Sun L, Cao L
Frontiers in immunology 2025;16:1658679

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Signaling intact membrane-bound IL-15 enables potent anti-tumor activity and safety of CAR-NK cells.

Xu X, Cao P, Wang M, Wan Y, Sun S, Chen Y, Liu Y, Su T, Gao G, Liu X, Zhong W, Chen X, Lu X, Chen B, Zheng J, Wang G, Li H
Frontiers in immunology 2025;16:1658580

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Effects of dietary supplementation with fermented Astragalus membranaceus on growth performance, antioxidant capacity and intestinal barrier function of common carp (Cyprinus carpio).

Han Y, Ma B, Wangshao M, Wang X, Guo J, Su X, Guo S, Yang G, Pan J, Shi H
Frontiers in immunology 2025;16:1658061

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Targeting PSMB5-induced PANoptosis in bladder cancer: multi-omics insights and TCM candidate discovery.

Chang Z, Wang J, Cao J, Fan X, Li K, Wang C, Zhang Y, Wang L, Yang J, Chen S, Yang L
Frontiers in immunology 2025;16:1656682

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Plasma-derived exosomal miRNAs as potentially novel biomarkers for type 2 diabetes mellitus with abdominal obesity.

Li Y, Wang Y, Li Z, Feng L, Feng R, Jia J, Xing L, Zheng L
Frontiers in endocrinology 2025;16:1656132

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Inhibition of HMGB1/NF-κB signaling restores Th17/Treg balance via dendritic cell modulation in liver transplant rejection.

Li L, Wang J, Huang L, Chen Y, Chen L
Frontiers in immunology 2025;16:1649366

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Isorhamnetin attenuates renal interstitial fibrosis by targeting TWEAK/Fn14-mediated epithelial-mesenchymal transition.

Chen Y, Luo W, Guan H, Chen Z, Chen Z, Xiao L, Xu W, Huang M, Lin Y, Zhang Y, Peng W, Nan L
Frontiers in immunology 2025;16:1649327

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PSD3 as a context-dependent modulator of immune landscape and tumor aggressiveness in esophageal squamous cell carcinoma.

Luo S, Li H, Cai B, Nurbahati A, Cui H, Peng T, Wang W, Liu Q, Lu X, Zheng S
Frontiers in immunology 2025;16:1641254

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Machine learning identifies PYGM as a macrophage polarization-linked metabolic biomarker in rectal cancer prognosis.

Xu C, Zhang S, Sun B, Yu Z, Liu H
Frontiers in immunology 2025;16:1639303

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Identify GDPD3 as a key regulator of epithelial-mesenchymal transition and prostate adenocarcinoma progression via the LPA/LPAR1/AKT axis: transcriptomic and experimental study.

Hao L, Chen X, He T, Wu T, Wen Z, Ji Z, Zheng X, Zheng Q, Zhou Q, He C, Long Q, Sun D
Frontiers in immunology 2025;16:1637325

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Integrative bioinformatics and experimental validation unveil CRISP3 as a hypoxia-, epithelial mesenchymal transition-, and immune-related prognostic biomarker and therapeutic target in breast cancer.

Ren Y, Li Y, Wang Z, Cui Y, Xing Z, Zhang Y, Cao N, Yu Y, Guo Y, Li X
Frontiers in immunology 2025;16:1634399

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Passive hydrotherapy preserves cartilage and muscle integrity in a murine osteoarthritis model: potential role of integrin αV/TGF-β mechanotransduction.

Di W, Songyang W, Ruibing F, Yong H, Hao H, Xiaofeng D, Yang R, Yunxiang D, Gang W
Frontiers in physiology 2025;16:1633618

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Fangchinoline attenuates hepatic fibrosis by regulating taurine metabolism and oxidative stress.

Yin H, Lian H, Wang Y, Chen L, Liu X, Liu Y
Frontiers in pharmacology 2025;16:1633519

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Exosomal circ_0093708 as a potential ferroptosis biomarker in cerebral ischemia-reperfusion injury.

Ma S, Zhang X, Fan J, Chen M, Yao Q, Zhang N, Shi K, Du S, Cheng Y, Qu H, Duan M, Yang H, Gao T, Zhan S
Frontiers in neurology 2025;16:1633393

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Single-cell and multi-omics analysis identifies TRIM9 as a key ubiquitination regulator in pancreatic cancer.

Chen L, Ying X, Ma C, Tang Q, Chen S
Frontiers in immunology 2025;16:1631708

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Non-invasive physical plasma activates stimulator of interferon genes pathway in triple negative breast cancer and is associated with increased host immune response.

Wang G, Arnholdt M, Koch A, Enderle MD, Hahn M, Brucker SY, Weiss M
Frontiers in immunology 2025;16:1631530

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Ginsenoside Rb1 mitigates atherosclerosis in part through modulating FTO-mediated m(6)A RNA modification in NETs-induced endothelial activation.

Yang Z, Xiong M, Tang X, Wang P, Cui J, Chen Y, Zhang T
Frontiers in pharmacology 2025;16:1631076

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Identification and validation of the VEGF/p38MAPK/HSP27 pro-tumor inflammatory pathway: screening of active components from Patrinia villosa and evaluation of their drug-likeness.

Li X, Ju Y, Yang X, Li T, Wang S, Bao Y, Meng X
Frontiers in immunology 2025;16:1631031

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3D-cultured hADSCs-derived exosomes deliver circ_0011129 to synergistically attenuate skin photoaging.

Zhang Y, Zhou F, Nie G, Li L, Wen J, He S, Yao A
Frontiers in genetics 2025;16:1627472

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High-expression of BCL10 inhibits cell-mediated immunity within the tumor immune microenvironment.

Gu J, Chen C, Chen Y, Lv W, Li F, Zhu P, He P, Du Y, Liu H, Zhu B
Frontiers in immunology 2025;16:1616321

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The protective effect of Blautia coccoides in secondary injury of intracerebral hemorrhage.

Shao X, Zheng M, Ye C, Lu J, Li M, Su K, Lin H, He L, Qi X, Wang J
Frontiers in microbiology 2025;16:1616222

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Lumefantrine ameliorates DSS-induced colitis by targeting FLI-1 to suppress NF-κB signaling.

Yang J, Guo P, Luo H, Tang X, Liu W, Ren X
Frontiers in pharmacology 2025;16:1614978

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Quercetin inhibits the cAMP/PKA/CREB/glycolysis axis to exert anti-acute lymphoblastic leukemia effects.

Ma Q, Liu W, Su Y, Guo J, Zhang M, Guo J, Liu M, Dong W, Li M, Wang B
Frontiers in pharmacology 2025;16:1614973

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PLK2 as a key regulator of glycolysis and immune dysregulation in polycystic ovary syndrome.

Ma H, Qi D, Xu Y, Shang T, Si Y, Chen W, Zhao H, Ren Q
Frontiers in immunology 2025;16:1610713

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Jiannao Pills alleviate depression-like behavior in chronic unpredictable mild stress-induced mice through NF-κB/NLRP3 pathway.

Pan J, Liu J, Fan Q, Gao S, Liang Y, Zhang L
Frontiers in pharmacology 2025;16:1606445

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Network pharmacology-based prediction and "gut microbiota-inflammation-brain axis" validation of the active ingredients and potential mechanisms of Plantagins Herba for treating diabetes-related cognitive dysfunction.

Huang Z, Liu J, Li H, Ai Y, Zhou D
Frontiers in pharmacology 2025;16:1601689

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Revealing the significance of tissue-resident memory T cells in lung adenocarcinoma through bioinformatic analysis and experimental validation.

Li Z, Tian M, Yang Y, Wang Y, Zhang L, Huang F, Wen X, Yin X, Lin X, Tian Y
Frontiers in immunology 2025;16:1600863

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ScRNA-seq combined with ATAC-seq analysis to explore the metabolic balance mechanism of CCl4-induced liver inflammatory injury.

Liu H, Zhang Y, Ning S
Frontiers in immunology 2025;16:1600685

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Wuhan strain of SARS-CoV-2 triggers activation of immune evasion machinery similar to the one operated by cancer cells.

Abooali M, Yasinska IM, Thapa G, Lei X, da Costa KAS, Schlichtner S, Berger SM, Fasler-Kan E, Temperton NJ, Vuono R, Sumbayev VV
Frontiers in immunology 2025;16:1599352

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miR-223 alleviates DSS-induced colitis by prompting macrophage M2 polarization through PPAR-γ/FOXO1 signaling.

Zhang J, Wang L, Shen Y, Qian X, Wang Z, Wang C
Frontiers in immunology 2025;16:1598781

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Uncovering the mechanism of resveratrol in the treatment of asthma: a network pharmacology approach with molecular docking and experimental validation.

Chunxiao L, Xin H, Bowen L, Bingqing S, Mengqi Z, Shuwen Z, Jingyuan Z, Jiangtao L
Frontiers in pharmacology 2025;16:1596737

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Tetramethylpyrazine enhances neuroprotection and plasticity in cerebral ischemia-reperfusion injury via RhoA/ROCK2 pathway inhibition.

Zhang Y, Zhang X, Shi X, Liao W, Lin J
Frontiers in pharmacology 2025;16:1594283

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Glutaredoxin2 reduces age-associated B cell differentiation through maintaining redox homeostasis.

Jiang Y, Sun C, He Q, Liu S, Tian S, Zhang Y, Du Y, Li F, Zhang H
Frontiers in pharmacology 2025;16:1593816

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Construction and validation of a necroptosis-related lncRNA signature for predicting the prognosis of gastrointestinal cancer patients.

Huang W, Liu Y, Liu R, Feng C, Wu J, Sun X, Zhu P, Chen P, Cheng Y
Frontiers in immunology 2025;16:1591252

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LL37 promotes angiogenesis: a potential therapeutic strategy for lower limb ischemic diseases.

Yang Y, Wu G, Wang Y, Mao Q, Zhang D, Wu J
Frontiers in pharmacology 2025;16:1587351

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Palmitoylation-driven immune dysregulation and prognostic signature in low-grade glioma: a multi-omics and functional validation study.

Wang Z, Yu T, Liu Y, Wu Y, Hu J
Frontiers in pharmacology 2025;16:1586921

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Fatty acid metabolism after short-term fasting: POMC response and EPA signal maintain homeostasis in tilapia.

Yu X, Zhu T, Yu Y, Cai R, Li M, Sun C, Li W
Frontiers in endocrinology 2025;16:1585216

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Identification and validation of DNA methylation-driven gene OSR1 as a novel tumor suppressor for the diagnosis and prognosis of breast cancer.

Xu J, Yang B, Cheng L, Gan C, Huang R, Li A, Ge H, Hu L, Ling M, Zheng X, Zhao B, Zhang M, Cheng H
Frontiers in genetics 2025;16:1583620

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Bioactive compound combinations from Rhodiola tangutica alleviate pulmonary vascular remodeling in high-altitude pulmonary hypertension rats through the PI3K-AKT pathway.

Yang N, Huayu M, Su S, Hou B, Yang Z, Nan X, Li Z
Frontiers in pharmacology 2025;16:1582677

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Interstitial fluid transport in linea alba is involved in acupuncture-induced attenuation of ovarian hypofunction in aged rats.

Zhu Y, Lu G, Li W, Su C, Du P, Wang S, Yang L, Xu H, Fang Y, Song X
Frontiers in endocrinology 2025;16:1579031

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8-Nitrotryptanthrin inhibits colorectal cancer progression via TGF-β/SMAD and PI3K/AKT/mTOR pathways.

Sun CY, Cong KP, Zhao DD, Fan EG, Guo MQ, Zhang ZG
Frontiers in pharmacology 2025;16:1576673

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Therapeutic effects and mechanisms of Xinmaitong formula for type 2 diabetes mellitus via GLP-1R signaling.

Pu W, Pan Y, Yang K, Gao J, Tian F, Song J, Huang Y, Li Y
Frontiers in pharmacology 2025;16:1575450

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Identification of an Ara-C resistance-related gene risk score and the role of S100A4 in AML via NR6A1-dependent activation and p53 regulation.

Wang L, Huang A, Cheng B, Hu X, Wang J
Frontiers in pharmacology 2025;16:1574759

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Androgen receptor inhibitor ameliorates pulmonary arterial hypertension by enhancing the apoptosis level through suppressing the Notch3/Hes5 pathway.

Sun J, Lin J, Yin D, Pan Z, Ye Y, Wang Y, Wang X, Guo Q
Frontiers in pharmacology 2025;16:1572489

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Investigation of Fructus sophorae extract's therapeutic mechanism in atrophic vaginitis based on network pharmacology and experimental validation.

Zheng J, Wang W, Song W, Zhang Y, Yao M, Wang G, Huang Z, Li F, Ren J, Lin L, Fan X, Liu J
Frontiers in pharmacology 2025;16:1571976

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Suppressed intestinal secondary bile acids in moxifloxacin-induced hyperglycemia: studies in normal and diabetic GK rats.

Sun Y, Qu Y, Yang Z, Lv B, Wang G, Fan K, Wang Y, Pan J, Du Z, Yu Y
Frontiers in pharmacology 2025;16:1569856

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Ganoderma lucidum spore powder alleviates rheumatoid arthritis-associated pain hypersensitivity through inhibiting accumulation, N1 polarization, and ROS production of neutrophils in mice.

Huang S, Zhan Z, Xu F, Liu X, Fang Z, Wu W, Liang Z, Liu G, Wang M, da Silva HS, Luo X, Mo K
Frontiers in immunology 2025;16:1569295

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The protective role of cannabidiol in stress-induced liver injury: modulating oxidative stress and mitochondrial damage.

Huang C, Liang H, Liang X, Liu Y, Wang J, Jiang H, Kou X, Chen J, Huang L
Frontiers in pharmacology 2025;16:1567210

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Impact of the ENPP1 mutation on bone mineralization and ectopic calcification: evidence from in vitro and in vivo models.

Wu W, Liu L, Shi Y, Zhang Y, Qiu R, Yan F
Frontiers in endocrinology 2025;16:1566392

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Gallic acid mitigates high-fat and high-carbohydrate diet-induced steatohepatitis by modulating the IRF6/PPARγ signaling pathway.

Qiu J, Fu L, Xue Y, Yang Y, Qiao F, Zhu W, Gao Y, Fang M, Liu Y, Gao Z, Guan Y, Gao Y, Zhang X, Shang Z
Frontiers in pharmacology 2025;16:1563561

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Bletilla striata polysaccharides ameliorate metabolic-associated fatty liver disease by decreasing the NLRP3 inflammasome and pyroptosis.

Yu T, Xue J, Tang W, Wu X, Li J, Yang F, Luo L
Frontiers in pharmacology 2025;16:1563275

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Carnosine alleviates oxidative stress to prevent cellular senescence by regulating Nrf2/HO-1 pathway: a promising anti-aging strategy for oral mucosa.

He H, Lv C, Xie Y, Li W, Ling Z, Cheng B, Tao X
Frontiers in pharmacology 2025;16:1559584

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Huoshan Dendrobium Zengye Jiedu Formula mitigates radiation-induced oral mucositis and improves oral immune microenvironment by targeting the EGFR/PI3K/AKT pathway: evidence from network pharmacology, molecular docking, and experimental validation.

Liu C, Liu X, Liu J, Zhang H, Zhang P, Huo X, Song H, Zhu Y
Frontiers in immunology 2025;16:1559400

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Revealing the mechanisms of warfarin-induced vascular calcification through metabolomics and network toxicology.

Zhang Z, Jia P, Feng C, Xu J, Zhang J, Bai N, Chen W, Gao W
Frontiers in pharmacology 2025;16:1554987

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Inhibition of colorectal cancer cell growth by downregulation of M2-PK and reduction of aerobic glycolysis by clove active ingredients.

Liu L, Xing G, Guo X, Chen H, Li J, Wang J, Li Y, Liang G, Liu M
Frontiers in pharmacology 2025;16:1552486

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Akkermansia muciniphila ameliorates olanzapine-induced metabolic dysfunction-associated steatotic liver disease via PGRMC1/SIRT1/FOXO1 signaling pathway.

Chen H, Cao T, Lin C, Jiao S, He Y, Zhu Z, Guo Q, Wu R, Cai H, Zhang B
Frontiers in pharmacology 2025;16:1550015

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Pan-cancer analysis reveals MTTP as a prognostic and immunotherapeutic biomarker in human tumors.

Wang W, Gao Y, Liu Y, Xia S, Xu J, Qin L, Jia Y, Qin Y
Frontiers in immunology 2025;16:1549965

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Hypoxia-induced tRF-3(Thr-CGT) promotes hepatocellular carcinoma progression via mitochondrial energy metabolism remodeling dependent on the mtDNA-translation mechanism.

Qu X, Liu B, Jin D, Ma Y, Liu M, Yan X, Su J, Zhou L
Frontiers in pharmacology 2025;16:1549373

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Identification of regulatory cell death-related genes during MASH progression using bioinformatics analysis and machine learning strategies.

Lin Z, Li W, Xu Y, Liu H, Zhang Y, Li R, Zhao W, Guan Y, Zhang X
Frontiers in immunology 2025;16:1542524

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Asperosaponin VI suppresses ferroptosis in chondrocytes and ameliorates osteoarthritis by modulating the Nrf2/GPX4/HO-1 signaling pathway.

Zhang Z, Yuan D, Jin X, Chang W, Zhang Y, Xie W
Frontiers in pharmacology 2025;16:1539092

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Wenyang Zhenshuai Granules inhibits cardiomyocyte apoptosis in chronic heart failure by regulating p38 MAPK signaling pathway through exosomal miR-155.

Peng L, Chen X, Cai H, Tang Y, Chen Q, Zhou F
Frontiers in pharmacology 2025;16:1538091

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High interleukin-35 expression is associated with the severity of rheumatic mitral stenosis.

Wang P, Li Y, Zhao L, Liu B, Cai Z, Zhang P, Li P, Gao X, Zhan Y
Frontiers in immunology 2025;16:1537497

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Inflammation and platelet hyperresponsiveness in coronary artery disease and the influence of Talin-1/αIIbβ3-mediated bidirectional signaling pathway.

Shi S, Gao J, Zhang Y, Zhan M, Tan Z, Wang P, Fu J, Liu J
Frontiers in pharmacology 2025;16:1535182

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Aqueous extracts of Elsholtzia ciliata and Hovenia dulcis ameliorate loperamide-induced constipation in mice by promoting intestinal peristalsis and barrier function and the abundance of intestinal beneficial bacteria.

Wu J, Xin Q, Wang S, Zhang X, Jiang C
Frontiers in microbiology 2025;16:1531232

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BNIP3-mediated mitophagy aggravates placental injury in preeclampsia via NLRP1 inflammasome.

Zhao M, Yang Z, Kang Y, Fang Z, Zhang C, Wang C, Zhou M, Guo J, Li A, Zhang M
Frontiers in immunology 2025;16:1530015

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Gut microbiota-derived metabolite phenylacetylglutamine inhibits the progression of prostate cancer by suppressing the Wnt/β-catenin signaling pathway.

Lv J, Jin S, Zhou Y, Fu C, Shen Y, Liu B, Li J, Li M, Zhang Y, Feng N
Frontiers in pharmacology 2025;16:1528058

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Metformin-mediated intestinal AMPK activation ameliorates PCOS through gut microbiota modulation and metabolic pathways.

Xu Y, Ning L, Si Y, Li X, Wang R, Ren Q
Frontiers in endocrinology 2025;16:1526109

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Identification of retinol dehydrogenase 10 as a shared biomarker for metabolic dysfunction-associated steatotic liver disease and type 2 diabetes mellitus.

Li F, Li R, Deng H
Frontiers in pharmacology 2025;16:1521416

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Identification of immune subtypes associated with CD8+ T cell-related genes providing new treatment strategies of esophageal carcinoma.

Wu Y, Lin C, Qian Y, Huang X, Xu Y, Li J, He Y, Xie C, Su H
Frontiers in immunology 2025;16:1512230

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Transcriptome analysis of 3D4/21 cells expressing CSFV NS4B.

Dong W, Lv H, Song Y, Lv Y, Xu X, Jing H, Peng Z, Song X, Guo Y
Frontiers in microbiology 2025;16:1510058

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Chlorogenic acid alleviates the intestinal barrier dysfunction and intestinal microbiota disorder induced by cisplatin.

Tian R, Ding Y, Zhang S, Li M, Wang Y, Wu Q, Ding H, Song C, Shi C, Xue M
Frontiers in microbiology 2025;16:1508891

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Gallic acid protects intervertebral disc cells from ferroptosis and alleviates intervertebral disc degeneration by regulating key factors of oxidative stress.

Zhu Z, Huang Z, Zhang C, Xu B, Chen H, Pei S, Zhang B, Jie L, Shi X, Liu Y, Li Y, Shen X
Frontiers in pharmacology 2025;16:1501725

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ER-α36 prevents high glucose-induced cellular senescence and apoptosis in renal tubular cell.

Yu D, Luo L, Liang Y, Zhou H, Xiao Y, An X, Wang Y, Xu Z, Sun W, Wang W
Frontiers in endocrinology 2025;16:1426854

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Loss of ATG5 impairs CD4+ T cell activation and promotes anti-tumor responses.

Plaza-Sirvent C, Bessen C, Bronietzki AW, Klages K, Schuster M, Huehn J, Schmitz I
Frontiers in immunology 2025;16:1284391

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Metabolic stress-induced dysregulation of the Hippo signaling pathway inhibits the occurrence of hepatocarcinoma.

Zhang S, Li L, Jin L, Li Z, Tao Q, Zhou F, Lu X, Zhang Q, Hu G, Huang L, Zhang L, Feng Q, Peng H, Yu Q
American journal of cancer research 2025;15(9):3854-3870

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The m6A modification of SOX18 leads to increased PTX3 and cardiomyocyte pyroptosis in sepsis-induced cardiomyopathy.

Sun H, Qiao X, Peng X, Zhu H, Zhang L, Jiang L, Wang L, Xue C, Yang J, Yi W, Zhang B, Liu J, Duan W
Theranostics 2025;15(8):3532-3550

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TFEB promotes Ginkgetin-induced ferroptosis via TRIM25 mediated GPX4 lysosomal degradation in EGFR wide-type lung adenocarcinoma.

Wang HJ, Dong LF, Ding LL, Miao XY, Zhang YW, Zhao LP, Yu LH, Guan ZR, Jiang YP, Tang XQ, Yan YX, Lou JS
Theranostics 2025;15(7):2991-3012

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Oncogenic non-V600 mutations evade the regulatory machinery of RAF including the Cdc37/Hsp90 chaperone and the 14-3-3 scaffold.

Wan X, Yap J, Chen J, Li Y, Faruk R, Tan NCB, Ma Y, Lim Y, Jubri KB, Hu J, Yuan J, Zhang G, Li Q, Yap YS, Lam P, Wang M, Fu NY, Hu J
Theranostics 2025;15(5):2035-2051

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Prognostic value, biological role, and mechanisms of LCN2 in childhood acute lymphoblastic leukemia.

Tang X, Li YY, Tan LJ, Gao J, Ma ZG, Guo X, Gu L, Liu HM
American journal of cancer research 2025;15(4):1759-1776

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Itaconate targets the ERK2 signal to suppress estrogen receptor-positive breast cancer cell growth.

Wang HC, Li YC, Hung MC
American journal of cancer research 2025;15(3):1133-1147

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Potential therapeutic targets for bladder cancer: a proteome-wide Mendelian randomization study.

Liu JH, Du YZ, Liu F, Yang L, Liu XQ, Fu B, Yang XR
American journal of cancer research 2025;15(3):1096-1108

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Cyclic mechanical stretching enhances mitophagy and oxidative stress resistance in adipose-derived stem cells via the Piezo1/ATP axis to accelerate wound healing.

Xiao Y, Shi Z, Yuan Y, Yao D, Feng R, Zhang Y, Zhao D, Zhang H, Sun P, Liu Y, Li Y, Shen X, Wang Z, Hu D, Guan H, Wang H
Theranostics 2025;15(18):9862-9884

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Saikosaponin D Mitigates Radioresistance in Triple-Negative Breast Cancer by Inducing MRE11 De-Lactylation via HIF1α/HDAC5 Pathway.

Li J, Feng L, Zhang L, Zhang W, Zhang Y, Liu X, Cai Q, Zhao W, Huang G, Lu C
Theranostics 2025;15(17):8935-8951

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Gut microbiota depletion accelerates hematoma resolution and neurological recovery after intracerebral hemorrhage via p-coumaric acid-promoted Treg differentiation.

Zheng Y, Li Y, He X, Zhu Y, Xu S, Feng Y, Kuang Y, Chen H, Fan L, Huang H, Hu L, Yu X, Wu J, Jin L, Hu J, Fu X, Zeng H, Cao S, Wang L
Theranostics 2025;15(14):6628-6650

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An AIM2 inflammasome biomimetic mineralization inhibitor for vascular dementia therapy.

Zhang Y, Jiang L, Wu R, Gao W, Zhang X, Liu L, Zhang Y, Lu J, Zheng Y, Cai X, Fu J
Theranostics 2025;15(13):6347-6368

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ZNF710 regulates the proliferation, migration, apoptosis, and cell cycle progression of gastric cancer cells through the Wnt/β-catenin pathway.

Zhou R, Zhou J, Cai J, Wen J, Wang F, Ma D, Luo Q, Yalikun A, Han J, Zhou X, Yu Y, Li Q, Wen Y
American journal of cancer research 2025;15(12):5266-5280

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Vine-inspired zinc-ion modified black phosphorus coating accelerates bone tissue infiltration of 3D printed scaffolds.

Li D, Dai D, Wang J, Wang Y, Tian Y, Zhang C
Theranostics 2025;15(11):5073-5086

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WDR3 drives pancreatic cancer metastasis by enhancing TGF-α mRNA stability through YTHDC1.

Chen L, You X, Yang C, Zhang Y, Di W, He Q
American journal of cancer research 2025;15(11):4923-4933

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A natural small molecule isoginkgetin alleviates hypercholesterolemia and atherosclerosis by targeting ACLY.

Zhang Z, Chen M, Xu Y, Wang Z, Liu Z, He C, Zhang F, Feng X, Ni X, Chen Y, Wang J, Liang X, Xie Z, Li J, Banach M, Pelisek J, Huo Y, Hu Y, Evans PC, Wang L, Tian XY, Xiao J, Shang Y, Zheng Y, Xian X, Weng J, Xu S
Theranostics 2025;15(10):4325-4344

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HPV11 targeting PPARA regulates the autophagy to inhibit the occurrence and development of nasal inverted papilloma.

Zhu G, Zheng L, He W, Chen X, Huang S, Jin M, Zhang Y
Frontiers in oncology 2025;15:1743808

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Prognostic value and experimental validation of atherosclerosis-derived pathogenic genes in colorectal cancer.

Li Y, Wei J, Xu Y, Wu Z, He S, Zhu Y, Ni W, Zhang D, Xu H, Zhang C, Zhou A, Shen T, Li J
Frontiers in oncology 2025;15:1728087

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MiR-424-5p acts as an oncogene in Hep3B cells by activating the PI3K/AKT signaling pathway.

Ding Z, Qi S, Hu M, Wang L, Tang Y, Sun J, Zheng L, Li Y, Li L, Ma Q, Tang H
Frontiers in oncology 2025;15:1726596

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Spatial transcriptome and single-cell sequencing reveal the role of nucleotide metabolism in breast cancer progression and tumor microenvironment.

Pan Y, Xu Y, Gong K, Yuan S
Frontiers in oncology 2025;15:1703778

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LncRNA ELDR promotes bladder cancer malignant progression by regulating the miR-1343-3p/TRIM44 axis.

Hu X, Xie T, Xiao X, Mei Y
Frontiers in oncology 2025;15:1685792

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Periodontitis-associated metabolite isoleucine impairs intestinal barrier function and exacerbates intestinal inflammatory response by NF-κB signaling.

Wang X, Luo Y, Ren J, Xie H, Rausch MA, Rausch-Fan X, Hu F, Zhang X
Frontiers in cellular and infection microbiology 2025;15:1684362

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Ferroptosis's Master Switch GPX4 emerges as universal biomarker for precision immunotherapy: a pan-cancer study with in vitro experiments validation.

Li X, Zhu M, Dong R
Frontiers in oncology 2025;15:1643235

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Hypoxia promotes pancreatic adenocarcinoma progression by stabilizing ID1 via TRIM21 suppression.

Cheng R, Tang Y, Cao X, Huang Z, Guo Y, Jin R, Wang Y, Liu Y, Xue L, Wang Y
Frontiers in oncology 2025;15:1616968

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Molecular mechanism of LncRNA MALAT1 in regulating hepatocellular carcinoma progression via the miR-383-5p/PRKAG1 axis and its role in the tumor immune microenvironment.

Zhang R, Li M, Lu S, Wang A, Zhang S
Frontiers in oncology 2025;15:1613596

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Betrixaban is a broad anti-virus inhibitor by activating innate immunity.

Hu S, Zhao Y, Chen X, Wang H, Hu W, Huang R, Yang J, Niu C, Guo X, You F
Frontiers in cellular and infection microbiology 2025;15:1603530

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Comprehensive analysis of MGLL as a novel diagnostic and prognostic biomarker for clear cell renal cell carcinoma.

Chen C, Hu Z, Zhao W, Ma Y, Xia Q
Frontiers in oncology 2025;15:1594540

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Bioinformatics and experimental unveiling of TIMP1 as a novel therapeutic target in colorectal cancer ferroptosis.

Tang C, Li Z, Song T, Lu L, Chen B, Zhang T, Zhang Y, Yang J, Lao J, Chen H
Frontiers in oncology 2025;15:1593107

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TFRC promotes the proliferation, migration, and invasion of osteosarcoma cells by increasing the intracellular iron content and RRM2 expression.

Ren G, Zhou J, Su Y, Yang Q, Li J
Frontiers in oncology 2025;15:1567216

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Screening and identification of protein 29 of Echinococcus granulosus interacting molecules.

Shang Z, Qiao F, Li Y, Ma X, Wang M, Yang W, He T, Ma H, Wang Y
Frontiers in cellular and infection microbiology 2025;15:1560436

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WGCNA-ML-MR integration: uncovering immune-related genes in prostate cancer.

Lv J, Zhou Y, Jin S, Fu C, Shen Y, Liu B, Li M, Zhang Y, Feng N
Frontiers in oncology 2025;15:1534612

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Identification and validation of monocyte to macrophage differentiation-associated as a prognostic biomarker in gastric cancer.

Bai S, Chen Z, Ji R, Wang Y, Zhou Y, Guo Q, Qiao L
Frontiers in oncology 2025;15:1508355

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PIGR predicts good clinical outcomes and plays a tumor suppressor role in the development of breast cancer.

Jiang T, Sun Z, Dong K, Pu Q, Gao H, Lv Y, Li P, Zhao G
Frontiers in oncology 2025;15:1439120

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IgG promotes TNF-α induced osteoclastogenesis by upregulating the expression of TNFR1 and the NF-κB signalling pathway.

Yin H, Teng Y, Deng GM
Clinical & translational immunology 2025;14(5):e70034

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Fracture-Induced Immunological Cascades Trigger Rapid Systemic Bone Loss via Osteocyte-Regulated Osteoclastogenesis.

Sun L, Kuang S, Li Y, Wang G, Sun J, Zhou F, Zhang C
ImmunoTargets and therapy 2025;14:849-875

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PCK1 as a potential hub gene in distinguishing lactate metabolism between rheumatoid arthritis and osteoarthritis.

Xin P, Pei S, Ma N, Xiao L
PeerJ 2025;13:e19661

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Potential diagnostic markers and therapeutic targets for periodontitis with comorbid infective endocarditis based on bioinformatics and experimental analyses.

Mei F, Zhang W, Wang X, Liu Y, Zhou X, Zhou T, Zhang W
Frontiers in cell and developmental biology 2025;13:1725544

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CRISPR/Cas9-mediated CH2 deletion of Fel d1 triggers transcriptomic reprogramming and disease-associated pathways in feline cells.

Qu LY, Quan FS, Shi SM, Chi ZC, Chen J, Jin YX, Zhang MJ, Kong IK, Yu XF
Frontiers in cell and developmental biology 2025;13:1716808

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L-cysteine mitigates busulfan-induced testicular injury through modulation of CBS/H(2)S axis.

Liu S, Wei B, Wei H, Xu A, Sheng L, Sun X, Dong Y, Yang H
Frontiers in cell and developmental biology 2025;13:1679330

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Reduced Wiskott-Aldrich syndrome protein expression in preeclampsia placenta impairs trophoblast syncytialization by modulating syncytin-2 via FAK/β-catenin pathway.

Zhang S, Wang J, Ge Y, Cao P, Bai Z, Shen H, Wang D, Qiao C
Frontiers in cell and developmental biology 2025;13:1678878

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Exploring the effect and mechanism of fucoidan on liver cancer depending on network pharmacology and experimental verification.

Li X, Yang C, Wang L, Ullah I, Liu X, Feng C, Liu Q
Frontiers in chemistry 2025;13:1638785

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Comprehensive analysis of the papillary thyroid carcinoma identifies CSGALNACT1 as a proliferation driver and prognostic biomarker.

Zhao Y, Zhang J, Yao Y, Yu L
Frontiers in cell and developmental biology 2025;13:1638348

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Isowighteone attenuates vascular calcification by targeting HSP90AA1-mediated PI3K-Akt pathway and suppressing osteogenic gene expression.

Mo Y, Jin A, Hong W, Peng J, Yang R, Song Q, Liu Y, Cheng Y, Wong WT, Huang Q, Jiang L, Xu Z, Tan N
Frontiers in bioengineering and biotechnology 2025;13:1636883

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IL-6 signaling is required for the development and regeneration of ear cartilage in microtia.

Luan W, Fan S, Jiang H, Jiang D, Yang J, He L
Frontiers in cell and developmental biology 2025;13:1625058

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Endothelial GNAQ p.R183Q mutation confers hemoporfin-mediated photodynamic therapy resistance and drives pathological angiogenesis via the angiopoietin-2/TIE2/PI3K/AKT pathway.

Liu L, Wang L, Luo J, Yu J, Xie L, Liu Y, Xu H, Hu F, Liu H
Frontiers in cell and developmental biology 2025;13:1622961

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Tcirg1 deficiency delays osteoarthritis progression by impairing lysosome acidification and peripheral accumulation in osteoclasts.

Sun R, Yang Y, Ma Q, Wu G, Lan Z, Xue D, Chen Z, Su Y, Tuo Z, Yan J, Ma L, Zhao X, Tian K, He X, Ma Y, Lin X, Jin Q
Frontiers in cell and developmental biology 2025;13:1621648

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Multi-transcriptomics analysis of ferroptosis related genes reveals CAFs exosomal COX4I2 as a novel therapeutic target in osteosarcoma.

Niu X, Zhang X, Li Z, Tian W
Frontiers in cell and developmental biology 2025;13:1620648

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Methylglyoxal induces oxidative stress and ferroptosis of renal tubular epithelial cells in acute and chronic kidney injury mice.

Zhang Y, Zhang X, Ren J, Sun H, Yang Z, Wang J
Frontiers in cell and developmental biology 2025;13:1604575

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TRAF2 regulates the progression of pulmonary fibrosis through β-catenin-Snail signaling pathway.

Wan Z, Gu J, Duan W, Chen Y, Song S, Luo J, Zhang X, Yang Y, Gao F, Xu Y
Frontiers in public health 2025;13:1582860

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PDGF-BB overexpressing dental pulp stem cells improve angiogenesis in dental pulp regeneration.

Jiang W, Duan S, Li W, Yan H, Si C, Xu N, Li Y, Zhang W, Gu S
Frontiers in bioengineering and biotechnology 2025;13:1578410

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Assessing the prognostic and therapeutic value of cuproptosis-related genes in colon adenocarcinoma patients.

Ye Z, Song Y, Zhu M, Zheng F, Qin W, Li X, Wang P, Li Z, Chen K, Li A
Frontiers in cell and developmental biology 2025;13:1550982

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Hypoxia-induced immunosuppression in uveal melanoma is mediated by CD63(+) exosomes delivering lactate to reprogram immune cells.

Dong L, Zheng S, Feng Y
Frontiers in molecular biosciences 2025;12:1743009

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Glycoprotein M6B suppresses the maintenance of glioma stem cell stemness and proliferation via the integrin β1/β-catenin pathway.

Chen Y, Fan Y, Run X, Liu M, Jiang S, Miao Z, Tian W
Frontiers in molecular biosciences 2025;12:1731116

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Vitamin K protects against lipopolysaccharide-induced intestinal inflammation in piglets by inhibiting the MAPK and PI3K-AKT pathways.

Wang H, Ma R, Qi R, Liu Z, Li Y, Wu X, Zhao C, Ma Q, Zhan K
Frontiers in nutrition 2025;12:1704168

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KLF4 orchestrates a Ccl2+ fibroblast-mediated inflammatory network driving preterm birth.

Gao J, Chang Y, Su Y, Sun L, Wang F, Xin H
Frontiers in medicine 2025;12:1700275

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Calycosin inhibits porcine reproductive and respiratory syndrome virus replication and activates RIG-I/IRF3 signaling pathway.

Chang Y, Li Z, Wang M, Pei K, Chang X, Ma J
Frontiers in veterinary science 2025;12:1674259

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Potential mechanisms of zinc sulfate in inhibiting porcine reproductive and respiratory syndrome virus replication: attenuation of oxidative stress, inflammatory response, and apoptosis.

Yang H, Zhang C, Li Q, Wu Z, Sun N, Yin W, Fan K, Li H
Frontiers in veterinary science 2025;12:1663508

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Identification of anoikis-related genes and immune infiltration characteristics in Sjögren's syndrome based on machine learning.

Wang L, Zhou Z, Zhou X, Liu Y, Wang M
Frontiers in medicine 2025;12:1661259

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sIFITM1, sIFITM3, and sViperin antiviral proteins as inactivated CSFV vaccine adjuvants.

Liu S, Zhou W, Ye H, Qiu F, Gu R, Xu E, Chen JL
Frontiers in veterinary science 2025;12:1661103

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Tissue specific role of ABCA1 in lung cholesterol homeostasis under high-cholesterol diet.

Ma J, Gong Z, Lu H, Yang H, Wang S, Zhu Q, Liu H, Li Y, Zhang Y, Lian X
Frontiers in nutrition 2025;12:1649407

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Shenyuan granules improve cellular senescence through Klotho-mediated p16/p21 signaling pathway in diabetic kidney disease.

Guo X, Zhang S, Sun Q, Li H, Wang L
Frontiers in medicine 2025;12:1627412

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Shikimic acid attenuates oxidative stress-induced senescence in 3D4/21 cells by modulating PARP1 activity and DNA damage response.

Mo K, Wu C, Wu W, Zhang Y, Yang L, Li L, Huang X
Frontiers in nutrition 2025;12:1614148

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Metabolic reprogramming signature predicts prognosis and immune landscape in small cell lung cancer: MOCS2 validation and implications for personalized therapy.

Wang J, Sun P, Zhang F, Xu Y, Guo S
Frontiers in molecular biosciences 2025;12:1592888

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Nutrient restriction protects against valve interstitial cell calcification by upregulating ubiquitin mediated proteolysis.

Phadwal K, Tang Q, Kurian D, Tan X, Cawthorn WP, MacRae VE
Frontiers in cardiovascular medicine 2025;12:1586775

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Screening and characterization of DNA aptamers that modulate prime editing.

Wang M, Wu X, Huang X, Ye J, Gui Y
Frontiers in molecular biosciences 2025;12:1565459

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Mechanism of Ershen Zhenwu Decoction in ameliorating chronic heart failure via JNK/MAPK-regulated apoptosis: insights from network pharmacology and experimental validation.

Liu Y, Wang X, Zhang M, Cheng D, Zhu Z, Ge L, Cheng X
Frontiers in cardiovascular medicine 2025;12:1561963

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Bacteroides fragilis 839 ameliorates anti-tuberculosis drugs-induced liver injury by suppressing inflammation and regulating gut microbiota in mice.

Li Q, Wu C, Zhang K, Zhou Z, Li J, Bai J, Cao J, Shi X
Frontiers in medicine 2025;12:1538528

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IL-6/GATA2/SERPINE1 pathway is implicated in regulating cellular senescence after acute kidney injury.

Su H, Lin X, Paredong A, Yao C, Zhang Y, Geng M, Guan Y, Gong L, Jiang F, Lv Q, Shou S, Jin H
Frontiers in molecular biosciences 2025;12:1538526

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Low hydrostatic pressure promotes functional homeostasis of nucleus pulposus cells through the TRPV4/CRT/FA complex axis.

Hu J, Zhu Y, Pang Z, Li X, Zhang H, Li X, Gao Y, Wang Y, Li P, Zhou Q
Frontiers in medicine 2025;12:1531907

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Jianpi Yangzheng Xiaozheng granule induced ferroptosis to suppress gastric cancer progression through reprogramming lipid metabolism via SCD1/Wnt/β-catenin axis.

Wang X, Li J, Qin R, Yin Y, Li J, Lin S, Zou X
Frontiers in molecular biosciences 2025;12:1523494

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Nutrients regulation of skin cells from canines and cats via Wnt/β-catenin signaling pathway.

Sun X, Ma Y, Gao Y, Li J, Li Y, Lv L
Frontiers in veterinary science 2025;12:1486201

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Silencing NEDD4L Effectively Inhibits the Malignant Behaviors of Hepatocellular Carcinoma.

Dai J, Zhu T, Wan J, Liu R, Song Y, Zhang D, Wang X, Zhang H, Li W, Lin J, Zhu X, Liu Y
Journal of hepatocellular carcinoma 2025;12:1369-1391

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Extracellular vesicles derived from irradiated oral squamous cell carcinoma cells inhibits M2 macrophage polarization by the miR-198-5p/MYD88 axis.

Du X, Duan M, Zhang Y, Li R
International journal of radiation biology 2025;101(11):1117-1128

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Ciprofol exerts anti-tumour effects in hepatocellular carcinoma through the Raf-MEK-ERK signalling pathway.

Chen Y, Shi P, Zhou S, Yu K, Wang Y, Yao F, Zhang R, Liu X, Fang C, Tie X, Li J, Xu J, Xu J, Pan X
Translational gastroenterology and hepatology 2025;10:52

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A pectic polysaccharide from Lycium ruthenicum Murray alleviates dextran sulfate sodium-induced colitis in mice.

Dong D, Wang H, Bi H, Li Y, Gao T, Feng J, Li G, Guo S, Yuan H, Ni W
Current research in food science 2025;10:100955

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Lithocarpus polystachyus Rehd. leaves aqueous extract inhibits learning and memory impairment in Alzheimer's disease rats: Involvement of the SIRT6/NLRP3 signaling pathway.

Wu W, Yan Y, Yi T, Wei Y, Gao J, Gong Q
Ibrain 2025 Summer;11(2):228-244

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Hypoxia, cuproptosis, and osteoarthritis: Unraveling the molecular crosstalk.

Jiang Z, Li J, Shi M, Li Y, Sun N, Xi K, Li X, Zhao D, Leng X, Zhou Z, Dong H
Redox biology 2025 Sep;85:103757

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Discovery of a novel chalcone-derived covalent Keap1 binder for mitigating cisplatin-induced mitochondrial dysfunction and nephrotoxicity.

Deng Y, Xu L, Jiang Z, Chen L, Zhu G, Xu C, Chu X, Wang L, Niu X, Chen L, Xiao Z, Hu J, Ge G
Redox biology 2025 Sep;85:103737

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Hsp90 C-terminal domain inhibition enhances ferroptosis by disrupting GPX4-VDAC1 interaction to increase HMOX1 release from oligomerized VDAC1 channels.

Li J, Wu G, Su H, Liang M, Cen S, Liao Y, Zhou X, Xie G, Deng Z, Tan W, Li Y, Xiao W, Liu L, Zhang J, Zheng Z, Deng Y, Huang Y, Shi X, Liu Y, Zhang G, Chen X
Redox biology 2025 Sep;85:103672

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sPLA2-IB and PLA2R Mediate Aberrant Glucose Metabolism in Podocytes via Hyperactivation of the mTOR/HIF-1α Pathway.

Bao J, Dai B, Yang L, Liu Z, Jin Y, Zhao H, Pan Y
Cell biochemistry and biophysics 2025 Sep;83(3):3341-3351

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GSK3A promotes human adenovirus replication and phosphorylates viral L4-22K protein.

Lin Y, Zhu Y, Jing L, Chen Y, Xiao X, Lei X, Xie Z
Life science alliance 2025 Sep;8(9)

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ZNF460 enhances HADHB level by activating its transcription to promote the progression and pulmonary invasion of cutaneous T cell lymphoma.

He Q, Tian X, Mu Q
Archives of biochemistry and biophysics 2025 Sep;771:110472

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Pan-Cancer Analysis Identifies DIP2B as a Potential Biomarker That Inhibits Kidney Renal Clear Cell Carcinoma Progression.

Chen Y, Guo Y, Hu A, Xu Z, Bahadar N, Xue S, Chen N, Zhang H, Song J, Li X, Jiang J, Chen R, Lu X, Chen Q
IUBMB life 2025 Sep;77(9):e70046

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Melatonin Ameliorates Circadian Disruption-Associated Dry Eye via Modulation of BMAL1-REV-ERBα-IL-17 Axis and Ocular Surface Microbiota Homeostasis.

Wang B, Zeng H, Yang X, Zuo X, Liang L, Zhang R, Deng W, Ju R, Wang X, Yuan J
Journal of pineal research 2025 Sep;77(5):e70076

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Targeting MondoA-TXNIP restores antitumour immunity in lactic-acid-induced immunosuppressive microenvironment.

Xu N, Zhu Y, Han Y, Liu Q, Tong L, Li Y, Chen Z, Shao S, He W, Li M, Wang Y, Qiang S, Chai P, Du P, Zhao W, Wu L, Zhang P, He J, Li H, Cheng J, Jia R, Li B, Lu Y, Tong X
Nature metabolism 2025 Sep;7(9):1889-1904

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The VP5 protein of the oncolytic virus OH2 regulates nectin-3 molecule to modulate tumor cell apoptosis.

Xia W, Zhou Q, Wang X, Yang J, Ren X, Wu J, Zhang X, Liuwei J, Hu H, Liu B, Wang Y
Virology 2025 Sep;610:110580

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miR-223-3p Mitigates Mitochondrial Dysfunction and Cementoblast Apoptosis in Orthodontic Root Resorption via FoxO3.

He W, Xu L, Jiang W, Yao S, Fu Y, Cheng Z, Zhang D, Huang L
Journal of periodontal research 2025 Sep;60(9):923-936

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Exogenous oxidized phytosterol may modulate linoleic acid metabolism through upregulation of fatty acid desaturase in rats.

Koyama T, Osada K
Lipids 2025 Sep;60(5):303-315

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Introduced paeoniflorin reduces the main toxicity induced by diosbulbin B, the major toxic compound of Dioscorea bulbifera L.: involved inhibiting inflammation and ferroptosis.

Zhang T, Li B, Wang J, Wu X, Song L, Wang Y, Zhang Y, Li Y
Drug and chemical toxicology 2025 Sep;48(5):1080-1089

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Lipin1-dependent transcriptional inactivation of SREBPs contributes to selinexor sensitivity in multiple myeloma.

Wang JY, Chen MP, Jiang JX, Wan YK, Li X, Zhang YW, Fang Y, Huang HH, Qin ZY, Hou J
Acta pharmacologica Sinica 2025 Sep;46(9):2496-2508

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Wogonin attenuates septic cardiomyopathy by suppressing ALOX15-mediated ferroptosis.

Ye H, Wu L, Liu YM, Zhang JX, Hu HT, Dong ML, Ren J
Acta pharmacologica Sinica 2025 Sep;46(9):2407-2422

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miR-210-3p Ameliorates Metabolic Dysfunction-Associated Steatohepatitis-Related Fibrosis by Targeting ISCU and Induces Ferroptosis.

Dai Z, Sun Z, Chen Q, Li Y, Sun Y, Jiao M, Yin X, Liu R, Liang H, Zhu C
Liver international : official journal of the International Association for the Study of the Liver 2025 Sep;45(9):e70282

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METTL3 Mediates Wnt/β-Catenin Pathway in Epithelial-Mesenchymal Transition of 16HBE Cells Induced by Beryllium Sulphate.

Yan C, Li G, Huang L, Zhang Z
Journal of applied toxicology : JAT 2025 Sep;45(9):1787-1797

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ACSL5 regulated acetyl-CoA to promote bladder cancer cellular senescence via 53BP1 acetylation.

Luo Y, Zeng Y, Liu Y, Liu S, Dai Y, Pan W, Zhang L, Zhu R, Feng D, Du K, Zhang X, Jia B, Tian F, Zhou L, Gu C
Oncogene 2025 Sep;44(34):3096-3112

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REPS2 attenuates cancer stemness through inhibiting Wnt signaling by autophagy mediated degradation of β-catenin.

Liu L, Chen S, Lei Y, Lin Z, Zhou R, Zeng G, Zheng Z, Liu W, Zhou Q, Chen L
Oncogene 2025 Sep;44(33):2942-2955

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Condensates of synaptic vesicles and synapsin-1 mediate actin sequestering and polymerization.

Chhabra A, Hoffmann C, Aguilar Pérez G, Korobeinikov AA, Rentsch J, Hümpfer N, Kokwaro L, Gnidovec L, Petrović A, Wallace JN, Tromm JV, Román-Vendrell C, Johnson EC, Ranković B, Perego E, Volpi T, Fernández-Busnadiego R, Köster S, Rizzoli SO, Ewers H, Morgan JR, Milovanović D
The EMBO journal 2025 Sep;44(18):5112-5148

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Macrophages form dendrite-like pseudopods to enhance bacterial ingestion.

Fan C, Huang X, Mei J, Shi X, Zhang H, Liang C, Cui S, Xing Y, Cao B, Liu W, Liu H, Liu B, Chang W, Shao M, Wei GH, Liu YJ, Chen ZJ, Lin Z, Xu T, Jiu Y
The EMBO journal 2025 Sep;44(17):4772-4802

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Mechanism of SC targeting RhoA regulation and its potential value in gastric cancer therapy.

Ma H, Jiang P, Ma R, Zhao J, Wang Q, Xing Y, Cao C, Su Z
Biochemistry and biophysics reports 2025 Sep;43:102158

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Bioinformatics-based identification of mirdametinib as a potential therapeutic target for idiopathic pulmonary fibrosis associated with endoplasmic reticulum stress.

Chen J, Du Y, Yu Q, Liu D, Zhang J, Luo T, Huang H, Cai S, Dong H
Naunyn-Schmiedeberg's archives of pharmacology 2025 Sep;398(9):12449-12471

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ROCK-Mediated Actin Remodeling Contributes to the Reduced Proliferation and Migration of bEnd.3 Endothelial Cells Treated With Florfenicol.

Hu D, Shen Z, Hou X, Wan Z, Guo X, Chen L, Yin Z, Ning H, Ge Y
Journal of biochemical and molecular toxicology 2025 Sep;39(9):e70453

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Interplay mechanism of virus latency-reactivation by human cytomegalovirus UL82 protein with the host core histone H3K27 methyltransferase EZH2 of polycomb repressive complex 2.

Huo X, Xia S, Cheng B, Xiong W, Li Q, Yang X, Ran Y, Li H, Chen J
International journal of biological macromolecules 2025 Sep;322(Pt 3):146753

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Water-soluble polysaccharides derived from Poria cocos protect against LPS-induced renal injury through inhibiting the NF-κB-NOX4 signaling pathway.

Yu D, Ge K, Chen N, Wang Y, Xu H
International journal of biological macromolecules 2025 Sep;321(Pt 4):146626

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NDRG2 regulates milkfatbiosynthesis by targeting the AMPK/SREBP1 axis in bovine mammary epithelial cells.

Cheng J, Wang L, Li L, Kuang T, Su H, Ren K, Pan S
International journal of biological macromolecules 2025 Sep;321(Pt 4):146448

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Cuproptosis- and m6A-related lncRNA prognostic signature for breast cancer, in which Z68871.1 contributes to triple-negative breast cancer progression.

Zhang Z, Gao Z, Huang Q, Ling Z, Zhang L, Li M, Xu Y, Liu M
International journal of biological macromolecules 2025 Sep;321(Pt 2):146321

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Selective and iron-independent ferroptosis in cancer cells induced by manipulation of mitochondrial fatty acid oxidation.

Gao Y, Song Z, Gan W, Zou X, Bai Y, Zhao X, Chen D, Qiao M
Biomaterials 2025 Sep;320:123259

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CHAF1A Promotes Preadipocyte Differentiation and Contributes to Macrosomia in Gestational Diabetes Mellitus.

Xia D, Xu X, Zhang Y, Zhang C, Wang H
Reproductive sciences (Thousand Oaks, Calif.) 2025 Sep;32(9):3086-3102

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TTK promotes mitophagy by regulating ULK1 phosphorylation and pre-mRNA splicing to inhibit mitochondrial apoptosis in bladder cancer.

Chen K, Chen J, Cong Y, He Q, Liu C, Chen J, Li H, Ju Y, Chen L, Song Y, Xing Y
Cell death and differentiation 2025 Sep;32(9):1691-1706

---

Deacetylation of ANXA2 by SIRT2 desensitizes hepatocellular carcinoma cells to donafenib via promoting protective autophagy.

Sun L, He M, Liu D, Shan M, Chen L, Yang M, Dai X, Yao J, Li T, Zhang Y, Zhang Y, Xiang L, Chen A, Hao Y, He F, Xiong H, Lian J
Cell death and differentiation 2025 Sep;32(9):1630-1647

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The chromatin remodeling factor BAP18 promotes non-small cell lung cancer progression via the recruitment of β-catenin with the transcriptional coactivator complex ACTL6A-PAF1.

Hao J, Hu Q, Li X, Shi S, Na F, Zeng K, Li H, Zhao Y, Zhao M
The Journal of biological chemistry 2025 Sep;301(9):110596

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IL4I1 overexpression protects against nonalcoholic fatty liver disease in part by inhibiting the AKT/FOXO1 pathway-mediated Th17 cell differentiation.

Yang Y, Wang N, Chen Y, Ma T, Weng M, Wu H, Wu Q, Xie Y, Zhu C, Li W
The Journal of biological chemistry 2025 Sep;301(9):110560

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Ubiquitin-specific protease 7-mediated stabilization of discoidin domain receptor 1 drives progression of TP53-Mutant cancers.

Xue Y, Xiu B, Yang M, Zhang Y, Yang C, Zhang L, Yan Y, Luo X, Huang Y, Mei H, Li G, Zhou L, Chen Y, Zhang W, Qian C, Zhang P, Liu J, Liang A, Zeng Y, Yang J
The Journal of biological chemistry 2025 Sep;301(9):110515

---

CIAO1 as a crucial signature gene of cuproptosis in gastric cancer.

Qu J, Yang C, Zhou S, Zhao B, Tong Q, Zheng L
Oncology letters 2025 Sep;30(3):440

---

Curcumin ameliorates hyperuricemia and gout-induced damage via modulating the ROS-dependent NEK7-NLRP3 inflammasome activation.

Zhao Z, Tong X, Sun J, Lu J, Zhang G, Wang Q, Yang L
Smart molecules : open access 2025 Sep;3(3):e20250002

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A cellular model of TDP-43 induces phosphorylated TDP-43 aggregation with distinct changes in solubility and autophagy dysregulation.

Dopler MB, Abeer MI, Arezoumandan S, Cox K, Petersen TL, Daniel EH, Cannon CL 3rd, Bautista A, Blancher KD, Bland AM, Bond KJ, Davis DA, Francois JM, McCray EJ, Morgan JM, Pulliam JL, Robinson ZA, Taylor MJ, Dowell JA, Cairns NJ, Gitcho MA
The FEBS journal 2025 Sep;292(18):4870-4897

---

Comprehensive Pan-Cancer Analysis of TRNT1 as a Potential Biomarker for Breast Cancer.

Li X, Meng Y, Gu B
Journal of cellular and molecular medicine 2025 Sep;29(18):e70853

---

METTL3 Silencing Suppresses Cardiac Fibrosis Post Myocardial Infarction via m6A Modification of SMOC2.

He Y, Pan X, Liu Z, Zuo P, Sheng Z, Hao C, Tao Z, Chen Z, Song J, Ma G, Ling S
Journal of cellular and molecular medicine 2025 Sep;29(17):e70829

---

Noninvasive in vivo tracking of SPIONs-labeled CLDN18.2-targeted CAR-T cells in gastric cancer via magnetic particle imaging.

He M, Ge L, Hui H, Zhou Y, Tang Y, Shen L, Tian J, Wu B, Qi C, Du Y, Tang L
Translational research : the journal of laboratory and clinical medicine 2025 Sep;283:3-12

---

RNA-binding proteins mediate the maturation of chromatin topology during differentiation.

Dehingia B, Milewska-Puchała M, Janowski M, Rafiee MR, Abbas M, Piotrowska A, Senge J, Blaut P, Walsh D, Severino J, Chaudhury D, Iqbal S, Montiel-Manriquez R, Jankowska S, Zare P, Huber W, Xu J, Casellas R, Zimmermann T, Dłotko P, Krijgsveld J, Pękowska A
Nature cell biology 2025 Sep;27(9):1510-1525

---

STING inhibits LINE-1 retrotransposition through sorting ORF1p to lysosomes for degradation.

Huang Y, Xu F, Wang L, Mei S, Zhao F, Wang L, Xie Y, Wei L, Hu Y, Gao Z, Xue T, Fang J, Guo F
EMBO reports 2025 Sep;26(18):4607-4630

---

NMDA-Type Glutamate Receptor Activation Promotes Ischemic Arrhythmias by Targeting the AKT1-TBX3-Nav1.5 Axis.

He Y, Zhang H, Zhang Q, Sun Z, Sun X, Xia L, Zheng L, Wang L
Acta physiologica (Oxford, England) 2025 Sep;241(9):e70085

---

The Age-Associated Long Noncoding RNA lnc81 Regulates Ovarian Granulosa Cell Proliferation and Apoptosis Through TEAD2-CCN1/2 Pathway in Mice.

Ma Z, Luo R, Xue Y, Zheng L, Zhou C, Fang S, Hu N, Wang H, Cheng X, Luo T, Hu L
Journal of cellular physiology 2025 Sep;240(9):e70090

---

L-Tryptophan Produced by Bifidobacterium pseudocatenulatum NCU-08 Delays Aging in SAMP8 Mice by Activating the Sirt1/P53/P21/Rb Signaling Pathway.

Xu T, Wu X, Zhang Y, Cai Y, Zhang X, Zeng Q, Luo J, Wei J, Chen T
Aging cell 2025 Sep;24(9):e70166

---

Cuproptosis involvement in neonatal ischemic-hypoxic encephalopathy through the COMMD1/ATP7A signaling axis.

Luo J, Zhang X, Bharati L, Hua Z, Chen S, Dong Z
Biochemical pharmacology 2025 Sep;239:117054

---

PTBP1 acts as a tumor suppressor in glioma by promoting HMOX1-dependent ferroptosis.

Sun J, Xue B, Sun T, Xu X, Zhang D, Shan Z, Wang Y, Chen B
Biochemical pharmacology 2025 Sep;239:117041

---

ZLY032 mediated activation of Notch1/Hes1 signaling inhibits cardiomyocyte ferroptosis to protect against myocardial Ischemia-Reperfusion injury in mice.

Li HD, Liu DP, Gong MY, Zhang Y, Liu J, Ren JT, Cheng MX, Zhang YW, Wang H, Wang SY, Huang J, Feng X, Jiang SQ, Li X, Liu T, Yang MY, Liu W, Jiao L, Li MM, Zhang Y
Biochemical pharmacology 2025 Sep;239:117039

---

ALKBH5 reverses romidepsin-mediated anti-multiple myeloma activity via regulation of m6A modification of FOXM1.

Zhang Y, Cao X, Li W, Cui Z, Mao J, Yao R, Liu L
Biochemical pharmacology 2025 Sep;239:116998

---

Alexidine dihydrochloride enhances the sensitivity of human hepatocellular carcinoma to disulfidptosis via ATF4-DDIT3 activation.

Li M, Xu J, Du K, Wang G, Feng Y, Liu P
Free radical biology & medicine 2025 Sep;237:585-599

---

Phillygenin ameliorates myocardial ischemia-reperfusion injury by inhibiting cuproptosis via the autophagy-lysosome degradation of CTR1.

Chen G, Wei M, Zhao CY, Zhang AY, Su JB, Ni ZR, Cai WW, Hou B, Du B, Liu MH, Xu GW, Yang L, Xu AJ, Wen YY, Wang J, Zou H, Zhuang YY, Xing HY, He T, Li YF, Lu QB, Zhu J, Zhu XX, Li KL, Sun HJ
Free radical biology & medicine 2025 Sep;237:542-557

---

Mitochondrial transport of glutathione in diabetic retinopathy.

Kowluru RA, Malaviya P
Free radical biology & medicine 2025 Sep;237:357-368

---

Mitochondrial electron transfer chain activation in atrophic Muscle: Implications for calcium signaling and chondrocyte apoptosis in osteoarthritis.

Li A, Pang T, Yang J, Wang Y, Dong L, Zhou Z, Li Y, Leng X, Dong H, Wang Y
Free radical biology & medicine 2025 Sep;237:285-299

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Eremophilane sesquiterpenes from agarwood of Aquilaria agallocha with neuroprotective effect.

Xie Y, Zhang S, Chen T, Li C, Tong R, Xu H, Yang Y, Han Z, Wang Z, Yang L
Phytochemistry 2025 Sep;237:114527

---

The mTORC2 subunit RICTOR drives breast cancer progression by promoting ganglioside biosynthesis through transcriptional and epigenetic mechanisms.

Ansari MN, Jha SK, Khan A, Rajput K, Pandey N, Jain D, Tripathi R, Medatwal N, Sharma P, Datta S, Kar A, Pani T, Ali SA, Cholke K, Rana K, Snijesh VP, Mukherjee G, Deo SVS, Basak S, Mishra A, Prabhu JS, Mukhopadhyay A, Bajaj A, Dasgupta U
PLoS biology 2025 Sep;23(9):e3003362

---

Caerulomycin A disrupts glucose metabolism and triggers ER stress-induced apoptosis in triple-negative breast cancer cells.

Zhang Y, Su S, Xu X, He Z, Zhou Y, Lu X, Jiang A
Chinese journal of natural medicines 2025 Sep;23(9):1080-1091

---

KAT5 knockdown alleviates microglial inflammatory injury following acute cerebral ischemia through enhanced STAT6 activity.

Li Y, Peng L, Zhou Y, You Y, Jiang J, Luo Y
Brain research bulletin 2025 Sep;229:111467

---

Sevoflurane aggravates hypoxic-ischemic encephalopathy in preterm neonates via VGluT1 upregulation and myelinogenesis impairment.

Qin M, Shi D, Song X, Zhang R, Feng Z, Li L
Brain research bulletin 2025 Sep;229:111450

---

TBX21 knockdown attenuates neuroinflammation induced by intracerebral hemorrhage via the SIRT1-WDR5-H3K4me3 axis.

Zou Z, Liu Z, Zhang Z, Li X
Brain research bulletin 2025 Sep;229:111415

---

CD8(+)GZMK(+)CD27(+)CCR7(+) T cells mobilized by splenic sympathetic nerves aggravate brain ischemia‒reperfusion injury via CCL19-positive endothelial cells.

Bai Y, Ren H, Leng S, Yuan M, Jiang Y, Zhang S, Wang Y, Ju M, Wang Z, Xi W, Xu L, Zheng B, Li D, Huo X, Zhu T, Zhang B, Shen L, Zhang Y, Jiang W, Zhang JH, Han B, Yao H
Cellular & molecular immunology 2025 Sep;22(9):1061-1076

---

TIMP1 inhibits Rac1-mediated ROS production to ameliorate blood-spinal cord barrier disruption in amyotrophic lateral sclerosis.

Tang J, Kang Y, Chen Q, Zhang B, Shang N, Lan J, Wu L, Peng Y
Neurobiology of disease 2025 Sep;213:106987

---

PINK1 deficiency permits the development of Lewy body dementia with coexisting Aβ pathology.

Gao TY, Wang XZ, Xie YH, Wang T, Lu YB, Huang LL, Chen C, Zhang M, Ma X, Chen YL, Liang FX, Lou ZL, Li JS, Yu YF, Wu JB, Ma XR, Wang HL, Tang C, Zhang WP
Alzheimer's & dementia : the journal of the Alzheimer's Association 2025 Sep;21(9):e70730

---

EPG-5 regulates TGFB/TGF-β and WNT signalling by modulating retrograde endocytic trafficking.

Yuan C, Dong H, Wu C, Liu J, Wang Z, Wang X, Ren H, Wang Z, Lu Q
Autophagy 2025 Sep;21(9):1995-2008

---

14-3-3/HIP-55 complex attenuates cardiomyocyte apoptosis.

Jiang Y, Estau D, Qiao Y, Li Z
Journal of molecular and cellular cardiology 2025 Sep;206:91-101

---

Zinc Transporter 9 (ZnT9) Improves Obesity-Induced Asthenospermia by Attenuating Endoplasmic Reticulum Stress (ERS).

Liang C, Chen M, Mu Z, Tian X, Zhao W, Hu Y, Su J
Biological trace element research 2025 Sep;203(9):4648-4658

---

Gastrin-releasing peptide in the paraventricular nucleus exerts hypertensive effects in preeclampsia.

Wang X, Ali MA, Liu X, Zeng M, Zeng Z, Yuan M, Issotina Zibrila A, Liu S, Ping N, Kang Y, Li X, Liu J
Neurochemistry international 2025 Sep;188:106004

---

MSC-EVs alleviate sepsis-induced acute lung injury through inhibiting NET-triggered damage to adherens junctions of endothelial cells.

Shao Y, Wu D, Miao C, Zhang H
Molecular immunology 2025 Sep;185:6-17

---

Choline reduces inflammatory response and lipid accumulation in calf hepatocytes induced by NEFA via inhibiting ROS/ NF-κB/NLRP3 inflammasome axis.

Zhang R, Du X, Hu H, Chen J, Yu J, Wang L, Yao J, Liu S, Wang J, Cao Y
Molecular immunology 2025 Sep;185:116-126

---

Synergistic mechanisms of Banxia Xiexin decoction in overcoming chemoresistance and enhancing chemosensitivity in colorectal cancer.

Yue Y, Chen M, Qin Y, Qian Y, Cui T, Liu T, Su L, Li Z, Yan S
Fitoterapia 2025 Sep;185:106711

---

Flavonoids from the stems of Ammopiptanthus nanus and their in vitro and in vivo anti-inflammatory activities.

Zhang R, Yang Q, Sun Y, Zhang H, Zhang J, Lu X, Satiwald M, Zhang P, Jin Y, Ji J, Chen L
Fitoterapia 2025 Sep;185:106678

---

A novel synthesised STAT3 inhibitor exerts potent anti-tumour activity by inducing lysosome-dependent cell death.

Xu MX, Liu X, Zhang HL, Xu H, Ma X, Yang Y, Duan C, Tang S, Liu Y, Li C, Pei M, Xia J, Yang Y, Guo Y, Wang Y, Luo S, Ma J, Yang Z, Zhu XF, Xu CP
British journal of pharmacology 2025 Sep;182(17):4041-4057

---

USP48 protects against myocardial ischemia-reperfusion injury by stabilizing and upregulating CNN1 in type 1 diabetes mice.

Su JB, Chen G, Sun QY, Fu X, Wu LX, Qiu HB, Lv ZL, Hu JY, Wang Y, Zhuang YY, Sun HJ, Lu QB, Zhang JR, Zhu XX
Metabolism: clinical and experimental 2025 Sep;170:156326

---

Ganoderic acid T, a novel activator of pyruvate carboxylase, exhibits potent anti-liver cancer activity.

Lei B, Zhang M, Shi X, Feng N, Yin J, Dong R, Xie C, Zhu Y, Zhong JJ, Ni B
Metabolism: clinical and experimental 2025 Sep;170:156321

---

Nitration of Tyrosine Residue Y10 of Aβ(1-42) Ameliorates Aβ(1-42)-Induced Neurotoxicity and Memory Impairment In Vitro and In Vivo.

Zhao J, Chen J, Lu J, Shi Q, Wang Q, Gao Z, Zeng L, Liu Q
Journal of neurochemistry 2025 Sep;169(9):e70218

---

Stromal Stiffness-Regulated IGF2BP2 in Pancreatic Cancer Drives Immune Evasion via Sphingomyelin Metabolism.

Tang R, Zhang Z, Liu X, Liao Y, Chen Y, Xiao M, Li Y, Zhou C, Tan Z, Zhang C, Chen C, Rong Z, Liu Y, Li P, Du Q, He Q, Lei Y, Wu Z, Lu S, Xu J, Wang W, Shi S, Yu X
Gastroenterology 2025 Sep;169(4):615-631.e32

---

Downregulation of ANXA2 suppresses trophoblast cell invasion and migration through β-catenin pathway in preeclampsia.

Mei Z, Gong M, Lai J, Liu P, Wang Y, Du P, He F
Placenta 2025 Sep;169:60-71

---

Agathic acid derivatives including a novel ferroptosis inhibitor from the fungus Penicillium thomii.

Zhang Y, Wang H, Xiao J, Xu W, Liu W, Luo Z, Wu P, Yang X, Zhang Z, Cheng Z
Bioorganic chemistry 2025 Sep;164:108867

---

An SPR-based active ingredient recognition strategy for identifying PLK1-targeting withanolides as natural ferroptosis inducers.

Zhu R, Yan H, Xu W, Liang J, Xiang K, Liu Y, Yang Y, Li H, Chen L
Bioorganic chemistry 2025 Sep;164:108849

---

Regulatory role of ATF2 in trophoblast ferroptosis via the PI3K/Akt/Nrf2 pathway in gestational diabetes mellitus.

Xia D, Zhang Y, Zhang C, Wang H
Journal of diabetes investigation 2025 Sep;16(9):1720-1732

---

CHK1-S, a splicing variant of CHK1, suppresses chronic myeloid leukemia.

Lei H, Xu H, Wang Y, Wu Y
Leukemia research 2025 Sep;156:107922

---

Gut dysbiosis exacerbates inflammatory liver injury induced by environmentally relevant concentrations of nanoplastics via the gut-liver axis.

Xia S, Yan C, Cai G, Xu Q, Zou H, Gu J, Yuan Y, Liu Z, Bian J
Journal of environmental sciences (China) 2025 Sep;155:250-266

---

USP20 as a super-enhancer-regulated gene drives T-ALL progression via HIF1A deubiquitination.

Xu L, Zhang Z, Yu J, Ji T, Cheng J, Fei X, Chu X, Tao Y, Xu Y, Yang P, Liu W, Li G, Zhang Y, Li Y, Zhang F, Yang Y, Zhou B, Wu Y, Wei Z, Chen Y, Wang J, Wu D, Li X, Yang Y, Qian G, Yin H, Wu S, Zhang S, Liu D, Fan JJ, Shi L, Wang X, Hu S, Lu J, Pan J
Acta pharmaceutica Sinica. B 2025 Sep;15(9):4751-4771

---

Rosmarinic acid attenuates hyperuricemia via restoring hyperuricemia-induced renal and intestinal dysfunctions.

Jia L, Sun B, Nie A, Shi Y, Zhou Z, Zhu C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157084

---

Furongtongmai capsule alleviates neuroinflammation by downregulating the TLR4/MyD88/JNK pathway to promote the recovery of peripheral nerve compression.

Liu H, Zhang X, Gu Q, Zhao Y, Wang H, Li H, Zhou T, Zhang Y, Zhao J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157082

---

Multi-omics analyses reveal that hesperidin ameliorates high-altitude pulmonary hypertension by restoring gut-lung axis homeostasis.

Fang L, Yang T, Nijiati Y, Shahanati D, Abudukeremu A, Li J, Shi W, Maimaitiyiming D, Aikemu A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157069

---

Lycopene ameliorates Di-(2-ethylhexyl) phthalate-induced neurotoxicity in mice via the gut-brain axis.

Chen LJ, Liu Y, Liu JL, Chen ZJ, Zhao W, Li JH, Hsu C, Chen L, Zeng JH, Li XW, Yang JZ, Li JH, Xie XL, Tao SH, Wang Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157057

---

Cannabidiol attenuates methamphetamine-induced oxidative neurotoxicity via regulating transient receptor potential vanilloid type 1.

Shen B, Yang G, Lv M, Wu Z, Zhang Y, Cao Y, Shu J, Dong W, Hou Z, Jing D, Xu J, Hou Y, Zhang X, Hong S, Li L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157015

---

Prophylactic administration of Xuesaitong soft capsule ameliorating depression-like behaviors in rats after ischemic stroke by modulating metabolic disturbance.

Lu R, Yang J, Fan R, Li H, Liu Y, Wang T, Yu Y, Zhang R, Liu Y, Liu J, Zhou N
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:156997

---

Dendrobium huoshanense improves atherosclerosis in high-fat-induced ApoE mice by regulating gut microbiota and serum metabolite profiles.

Zheng SJ, Gao XY, Diao XH, Chen ND
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:156964

---

Gut microbiota regulation by Lactiplantibacillus plantarum SG5 enhances mitochondrial function in Parkinson's disease mice via the GLP-1/PGC-1α pathway.

Qi Y, Xie S, Chen J, Zhang C, Ma X, Yu Y, Yu X, Wang Y
The Journal of nutritional biochemistry 2025 Sep;143:109954

---

Spliceosomal GTPase EFTUD2 mediates DDX41 intron retention to promote the malignant progression of ovarian cancer.

Liu Y, Chen Z, Duan Y, Shao Z, Chen Y, Yang N, Xiao H, Li Y, Song K
British journal of cancer 2025 Sep;133(4):508-523

---

Lactate induces oxidative phosphorylation in osteoblasts via Gpr81-Stat3 signaling.

Hu X, Shen J, Wang R, Han C, Shi X, Hu J, Zhang M, Wang P, Zhang X, Wu Y
Cellular signalling 2025 Sep;133:111877

---

PINK1 deficiency alleviates bleomycin-induced pulmonary fibrosis in mice.

Gu YQ, Wu J, Wang T, Yu YF, Han J, Chen YL, Hu XL, Wu M, Hu H, Zhang WP, Lu YB, Jiang B
Cellular signalling 2025 Sep;133:111868

---

Inhibition of IP3 (Inositol 1,4,5-Trisphosphate) Receptors Retards SARS-CoV-2-Induced Endothelial von Willebrand Factor Secretion and Thrombosis.

Yu XY, Jia XY, Wang TY, Zhang YH, Song H, Li K, Chen ZZ, Zhu Y, Yao L
Thrombosis and haemostasis 2025 Sep;125(9):847-858

---

Topoisomerase I Inhibition in ETV4-overexpressed Non-Small Cell Lung Cancer Promotes Replication and Transcription Mediated R-Loop Accumulation and DNA Damage.

Zhang J, Wang Y, Cao S, Xie SM, Liu B, Li Y, Hou Y, Meng X, Ruan M, Bu D, Kang J, Li R, Lou L, Wang J, Xing L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(35):e09307

---

Rictor Ameliorates Acute Antibody-Mediated Rejection Following Kidney Transplantation by Suppressing Macrophage M1 Polarization Through p65-NLRP3 Axis.

Ni B, Yang C, Zhang J, Hang Z, Zheng M, Feng D, Shen Q, Miao J, Sun X, Sun L, Shen B, Gu M, Wang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(34):e17119

---

HIGD1A Alleviates Oxidative Stress Related Ovarian Hypofunction by Enhancing Granulosa Cell Functions via NF-κB/SOD2 Signaling Pathway.

Li H, Cai S, Mu H, Chang T, Wang X, Tang T, Dong T, Zhang Y, Zhang L, Li H, Zhou L, Xiang W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(34):e03828

---

Splicing Shift of RAC1 Accelerates Tumorigenesis and Defines a Potent Therapeutic Target in Lung Cancer.

Yan Y, Wang N, Xing B, Yang M, Shang J, Bao Y, Xiao L, Zhang N, Ren Y, Liu C, Chen Y, Han H, Pan Y, Lv L, Zong WX, Ji H, Zhan C, Wang Z, Chen H, Wang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(33):e03322

---

Tumor-Associated Neutrophils Regulate Breast Cancer Progression Through the AQP9/STAT3 Signaling Pathway.

Xu W, Zhu G, Sheng Y, Zhang W, Wang S, Wu Q
Cancer science 2025 Sep;116(9):2374-2387

---

Catestatin attenuates cerebral ischemia/reperfusion injury and suppresses endoplasmic reticulum stress.

Zhang X, Fan J, Ma S, Zhang N, Shi K, Chen M, Duan M, Yao Q, Cheng Y, Du S, Qu H, Yang H, Gao T, Zhan S
Neuropeptides 2025 Sep;113:102550

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Mechanism of mitofusin 2, mitochondria-associated membrane, and the mitochondrial pathway in alleviating oxidative stress and cell senescence in bovine mammary epithelial cells.

Hu H, Liu J, Yin J, Hu G, Huang B, Tu L, Liu X, Xu B, Cao Y, Guo W, Fu S
Journal of dairy science 2025 Sep;108(9):10151-10172

---

Interaction of Newcastle disease virus V protein with EFTUD2 modulates MDA5 pathway to suppress viral replication.

Han Y, Zhang F, Zhou Z, Huang Y, Chen R
Poultry science 2025 Sep;104(9):105470

---

Investigation of the anti-inflammatory mechanisms of fermented Chinese herbal residue solution in an APEC-Infected HD11 cell model through the PI3K/AKT and NF-κB pathways.

Huang B, Mo S, He C, Zhu J, Tan Z, Chen L, Wang Y, Ma H
Poultry science 2025 Sep;104(9):105383

---

Suppressed autophagy of thymic cells promotes apoptosis and thymic atrophy in COPD.

He S, Yang Z, Xie L
Heart & lung : the journal of critical care 2025 Sep-Oct;73:180-189

---

Dexmedetomidine Up-regulates Brain-derived Neurotrophic Factor via Nrf2 in a Mouse Middle Cerebral Artery Occlusion Model.

Kim D, Hwang H, Shin H, Chung Y, Jun YH
In vivo (Athens, Greece) 2025 Sep-Oct;39(5):2609-2616

---

Membrane contact sites between chloroplasts and the pathogen interface underpin plant focal immune responses.

Yuen ELH, Savage Z, Pražák V, Liu Z, Adamkova V, King F, Vuolo C, Ibrahim T, Wang Y, Jenkins S, Zhou Y, Tumtas Y, Erickson JL, Prautsch J, Balmez AI, Stuttmann J, Duggan C, Rivetti F, Molinari C, Gaboriau DCA, Carella P, Zhuang X, Schattat M, Bozkurt TO
The Plant cell 2025 Sep 9;37(9)

---

Thyroidal expression of ER molecular chaperone GRP170 is required for efficient TSH-mediated thyroid hormone synthesis.

Zhang X, Young C, Liao XH, Refetoff S, Mutchler SM, Brodsky JL, Buck TM, Arvan P
JCI insight 2025 Sep 9;10(17)

---

Genome-wide mapping of RNA-protein associations through sequencing.

Qi Z, Xue S, Chen J, Zhao W, Johnson K, Wen X, Charles Richard JL, Lin P, Zhong S
Nature biotechnology 2025 Sep 9;

---

Tongxinluo alleviates myocardial ischemia-reperfusion injury by inhibiting the pyroptosis of endothelial cells via the NLRP3/Caspase-1/GSDMD signaling pathway.

Wu X, Hou YL, Wang TX, Chang LP, Zhou HR, Wang MY, Wu YL
Journal of molecular histology 2025 Sep 8;56(5):302

---

Synaptotagmin-like 5 is a potential biomarker and correlates with immune infiltrates in thyroid carcinoma.

Zhu X, Li X, Cui H, Wu H, Jiang D, Wang Y, Hua F
Journal of molecular histology 2025 Sep 8;56(5):300

---

Targeting the IRS1 macromolecular signaling node by Trienomycin a triggers cytoprotective autophagy in pancreatic adenocarcinoma.

Li MJ, Zhang R, Sheikho A, Tang JJ, Gao YQ, Huang WW, Gao JM
International journal of biological macromolecules 2025 Sep 8;328(Pt 2):147547

---

Design, synthesis and antitumor activity of pentacyclic triterpenoid Asiatic acid derivatives as Sp1 inhibitors.

Lu XH, Yu XR, Zhang LF, Han YT, Wu H, Wang Z, Meng YQ
Bioorganic & medicinal chemistry letters 2025 Sep 8;130:130398

---

Tumor nutrient stress gives rise to a drug tolerant cell state in pancreatic cancer.

Sheehan C, Hu L, Cognet G, Croley G, Nguyen TT, Thomas-Toth A, Agovino D, Jonker PB, Sadullozoda M, Ziolkowski LM, Martin JK, Beutel AK, Dano R, Khan MA, Halbrook CJ, Macleod KF, Weber CR, LaBelle JL, Muir A
bioRxiv : the preprint server for biology 2025 Sep 8;

---

Exosomes derived from human umbilical cord mesenchymal stem cells attenuate hepatic ischaemia-reperfusion injury via the let-7i-5p/Faslg axis.

Gao Y, He M, Bian CW, Yu R, Luo JJ, Xiang YM, Yang YX, Huang HF, Zeng Z
World journal of gastroenterology 2025 Sep 7;31(33):108653

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FGF5 alleviates ferroptosis in renal tubular epithelial cells by inducing mitophagy under in vitro ischemia-reperfusion-like injury.

Lin D, Wu T, Huang H, Hong X
Journal of molecular histology 2025 Sep 6;56(5):299

---

Uncovering citron kinase as a key biomarker for predicting outcomes and therapy efficacy in non-muscle-invasive bladder cancer.

Deng P, Zhong C, He P, Liu Q, Peng S, Liu R, Yu H, Li J, Wang Y, Yin W, Liu Y, Yang J, Zhong W, Lu J, Cai C
Gene 2025 Sep 5;963:149590

---

Fine particulate matter exacerbates asthma by activating STC2-mediated mitophagy through METTL3/YTHDF2-dependent m6A methylation.

Liu Y, Li G, Xiong A, Liu J, Zeng R, Zhang L, Wang J, Jiang M, Gao J, Xiong Y, He X
Journal of hazardous materials 2025 Sep 5;495:138854

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Aplf/Dna2 variants drive chromosomal fission and accelerate speciation in zokors.

Wan N, Duan Q, Cai Z, Zhu Z, Wang J, Tian Y, Shen W, Li B, Kuang Z, Liang X, Liu S, An X, Yang X, Liu X, Mao L, Chen J, Wang Y, Feng Z, Liu W, Bu Y, Nevo E, Papa R, Meyer A, Liu J, Li K
Science advances 2025 Sep 5;11(36):eadt2282

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Investigating the role of 1,8-Cineole in mitigating ferroptosis in a HFSD/STZ diabetes mellitus type 2-induced model: A GEO data analysis approach.

Yang H, Chen Y, Wu G, Ren P, Chen T, Liu J, Zhang B, Ma X, Jiang F, Li Y, Tao L, Shen X
European journal of pharmacology 2025 Sep 5;1002:177846

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Baicalein suppresses the malignant progression of acute myeloid leukemia via ROS-dependent metabolic reprogramming: Mechanisms of differentiation induction and ferroptosis activation.

Wang M, Wang Y, Chen L, Yu S, Li X, Huang G, Jin M
European journal of pharmacology 2025 Sep 5;1002:177839

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Glycyrrhizic acid mitigates hepatocyte steatosis and inflammation through ACE2 stabilization via dual modulation of AMPK activation and MDM2 inhibition.

Zhou L, Yi Y, Lin B, Qiu Z, Wang C, Li Y
European journal of pharmacology 2025 Sep 5;1002:177817

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Super-enhancers and Mef2c: Novel regulators of cardiac hypertrophy via the Hey2/Notch/p38 signaling pathway.

Wang R, Ba L, Wang R, Zhao Z, Wu N, Liu R, Feng X, Sun H, Qi H
European journal of pharmacology 2025 Sep 5;1002:177771

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Lithocholic acid ameliorates ulcerative colitis via the PXR/TLR4/NF-κB/NLRP3 signaling pathway and gut microbiota modulation.

Liu Y, Gao J, Chen L, Chen Y, Jiang J, Chen H, Ma L
Cellular and molecular life sciences : CMLS 2025 Sep 4;82(1):336

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Prepubertal Diabetes Stagnates Testicular Development by Skewing Autophagy Homeostasis in Leydig Cells.

Tang Z, Zheng Y
Cells 2025 Sep 4;14(17)

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O-GlcNAcylation of UBAP2L regulates stress granule formation and sunitinib resistance in clear cell renal cell carcinoma.

Xing J, Li B, Wang S, Wang Z, Miao C
Journal of experimental & clinical cancer research : CR 2025 Sep 30;44(1):273

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Role of Necroptosis and Neuroinflammation in CSVD-Associated Cognitive Decline in db/db Mice.

Wang DQ, Wang L, Zhao P, Gu YM, Xia XS, Li T, An N, Li X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 30;39(18):e70868

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NRF2 promotes the migration of ovarian cancer cell lines by targeting TAGLN mediated epithelial-mesenchymal transition.

Wang H, Zhang P, Cheng Q, Bao L
Journal of ovarian research 2025 Sep 30;18(1):213

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MRPL51 expression is associated with poor prognosis and regulates lung adenocarcinoma progression via neurotensin.

Zeng Q, Guo A, Hu H, Zhu X, Lu S, Xu J, Zheng C, He Z
Journal of thoracic disease 2025 Sep 30;17(9):7241-7261

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Development and validation of a necroptosis-related gene signature for predicting prognosis and immune infiltration in papillary thyroid cancer.

Wang S, Zhan X, Peng Y, Rao D, Yang M, Su Y, Cheng R
Translational cancer research 2025 Sep 30;14(9):5226-5244

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Osimertinib resistance-based immune prognostic related gene signature in EGFR mutant lung adenocarcinoma, in which PSMD11 promotes tumor progression.

Bai Y, Xu H, Bao P, Gao Y, Sun J, Shen Y, Zhao J, Jiang T
Translational lung cancer research 2025 Sep 30;14(9):3720-3739

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The lactylation of glucose-6-phosphate dehydrogenase promotes malignant phenotypes in cancer cell lines.

Zhang Y, Wu Y, Cheng A, Cui F, Yang Z, Guo J
Molecular biology reports 2025 Sep 3;52(1):861

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Long non-coding RNA HMGCR suppresses vascular remodeling in streptozotocin-induced type 1 diabetic rats via interaction with THOC5.

Chen SY, Xie X, Tong WQ, Niu BX, Li WX, He SY, Li NS, Jiang JL
European journal of medical research 2025 Sep 29;30(1):907

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Role of RET-Regulated GDNF-GFRα1 Endocytosis in Methamphetamine-Induced Neurotoxicity.

Lv M, Shen B, Wu Z, Yang G, Cao Y, Zhang Y, Shu J, Dong W, Hou Z, Jing D, Zhang X, Hou Y, Xu J, Li L, Hong S
International journal of molecular sciences 2025 Sep 29;26(19)

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Soy isoflavones improve sympathetic nervous system-driven non-alcoholic fatty liver disease through estrogen-like effects.

Yang J, Zhao Y, Ye Z, Liu Z, Chang L, Wang X, Qiao Y, Tong L, Cao Y
Food & function 2025 Sep 29;16(19):7644-7662

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Cytoplasmic TRIM24 promotes colorectal cancer cell proliferation by activating Wnt/β-catenin signaling.

Wang Y, Yao Y, Liu Z, Long S, Yi F, Fang Q, Wu D, Zhu Q, Zai H, Xiao S, Wan F, Fu K
Nature communications 2025 Sep 29;16(1):8598

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MSCs-EXOs containing miR-21a-5p promoted cell proliferation in the rat retinal Müller cell rMC-1 via targeting LATS1.

Deng L, Wang Y
Stem cell research & therapy 2025 Sep 29;16(1):529

---

MSCs-derived HGF alleviates senescence after AKI by modulating mitoSTAT3-controlled copper flux and respiration.

Zhuang K, Wang W, Xu C, Wang S, Chen Y, Zhang Y, Liang Y, Zheng X, Chen X, Feng Z, Cai G
Stem cell research & therapy 2025 Sep 29;16(1):526

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Ipriflavone Inhibits Porcine Reproductive and Respiratory Syndrome Virus Infection via RIG-I/IRF3-Mediated Interferon Signaling.

Chang Y, Li Z, Pei K, Wang M, Chang X
Animals : an open access journal from MDPI 2025 Sep 29;15(19)

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Effects of Tributyrin on Antioxidant Capacity, Immune Function, and Liver Macrophage Polarization in Weaned Piglets Under LPS Challenge.

Yuan M, Ning S, Yu D, Long F, Li W, Qi J, Liang Y, Hong C, Tang Y, Liu C, Wang G, Wu B, Zhong X
Animals : an open access journal from MDPI 2025 Sep 29;15(19)

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Nicotinamide metabolic dysregulation plays a key role in Benzo[a]pyrene-induced adverse birth outcomes: Evidence from multi-omics profiling, experimental and epidemiological validation.

Zhao N, Song W, Sun T, Wu W, Feng Y, Ma N, Wang S
Journal of hazardous materials 2025 Sep 28;498:140000

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Salecan Suppresses Pancreatic Cancer Progression by Promoting Necroptosis via the RIPK1/MLKL Pathway.

Du W, Xu R, Chen P, Wen J, Sun L, Chen X
Nutrients 2025 Sep 28;17(19)

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Piceatannol improves autoimmune hepatitis by inhibiting the immune activities of T cells and macrophages through binding with c-Jun.

Xu C, Lu C, Wang W, Wang Z, Qiu Y, Han M, Yang J, Li S
Immunologic research 2025 Sep 27;73(1):137

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Soluble urokinase plasminogen activator receptor promotes endoplasmic reticulum stress and apoptosis susceptibility through RAGE in sepsis acute kidney injury.

Wang B, Wang J, Qi C, Gao C, Wang Y, Zan Y, Tan Y, Wu Z, Jiang J, Suo J, Zhang J, Peng Z
Molecular medicine (Cambridge, Mass.) 2025 Sep 26;31(1):296

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Deciphering functional landscapes of rumen microbiota unveils the role of Prevotella bryantii in milk fat synthesis in goats.

Lei Y, Zheng Y, Yan Y, Zhang K, Sun X, Yang B, Ge L, Meng Z, Cao X, Zhang X, Yan X, Xu Y, Zhang T, Shi J, Chen S, Qiu Q, Chen Y, Deng L, Li Z, Wang X, Zhang K
Genome biology 2025 Sep 26;26(1):311

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Adiponectin pathway regulates cerebral metabolic dysfunction and neuroinflammation via the AdipoR1/PI3K/Akt axis in Perioperative Neurocognitive Disorder.

Zhang Z, Hu C, Li B, Zhong C, Guo L, Su B, Chen H, Xie H
BMC geriatrics 2025 Sep 26;25(1):721

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Synthesis and antitumor activity of steroid-based imidazolium salts.

Li T, Pan Y, Peng Y, Li A, Huang M, Fu L, Li Y, Zhang Z, Kong L, Deng G
RSC advances 2025 Sep 26;15(43):35913-35920

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Gene cloning of S100β and NGF and localization of their expression in the small intestine of broilers of various ages.

Han R, Tian X, Xu C, Qi F
Scientific reports 2025 Sep 26;15(1):32971

---

NPC1 as a novel therapeutic target for induction of pyroptosis in cancers.

Zhang C, Wang Q, Su P, Qian J, Guo Q, Wu W, Duan R, Zhang Y, Zu Y, Zhong L, Xiao L, Yi Q
Biomarker research 2025 Sep 26;13(1):115

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Engineering of an Exosome-Based GPIHBP1 mRNA Delivery System for Efficient Therapy of Familial Hypertriglyceridemia.

Cao Y, Meng X, Xu X, Xia C, Yang C, Cui X, He Q, Song G
Journal of medicinal chemistry 2025 Sep 25;68(18):19554-19566

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A novel function of RHOA as a host-dependent factor in Glaesserella parasuis infection of LLC-PK1 cells.

Zhou H, Chen X, Zeng X, Xie S, Zhang X, Zeng J, Xu K, Yu B, Liu H, Chen H
Veterinary research 2025 Sep 25;56(1):179

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Cantharidin-induced enterotoxicity: A molecular insight into intestinal barrier breakdown.

Liu R, Xiao Y, Shen Q, Yu J, Yang C, Zhang X, Tang W
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120468

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Mechanism study and clinical observation of Jia Wei Su Zi Jiang qi formula in reducing mucus hypersecretion in patients with chronic obstructive pulmonary disease.

Lu Q, Chen Z, Mu BX, Wang BH, Feng F, Zhao J, He H, Wei Y
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120363

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Protecting the brain from stroke: Huoxue Rongluo formula (HXRLF) targets ferroptosis for neuroprotection.

Ma Q, Luo L, Liao Y, Yang R, Ouyang X, Zhang Y, Yan S, Gong C, Liu L, Zhou D
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120329

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Caffeic acid ameliorates intestinal barrier injury to attenuate acute pancreatitis via inhibiting GSDMD-mediated pyroptotic pathway.

Zhang Y, Lin X, Shen B, Huang W, Zhou Q, Tan G, Zhi F, Liang E
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120261

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EMB is essential for enteric nervous system development mediated by PI3K signaling.

Li Z, Zhuansun D, Meng X, Yang H, Xiao J, Chen Y, Wang J, Yu X, Li Z, You J, Chen X, Feng C, Wu L, Chu X, Duan W, Wang K, Li Z, Tou J, Yu L, Tang W, Liu Y, Jiang X, Ren H, Yu M, Yin Q, Liu X, Xu Z, Wu D, Jiao C, Yu D, Wu X, Zhu T, Yang J, Xiang L, Wang J, Wang Q, Zhou B, Wang D, Chen K, Mao H, Wang B, Zhan J, Wang CY, Zeng W, Chen F, Xiong B, Feng J
Genome medicine 2025 Sep 25;17(1):102

---

The shutdown of food digestion due to endoplasmic reticulum homeostasis disruption acts as a protective mechanism in C. elegans.

He Y, Zhang Y, Xie H, Shan Z, Hou Z, Qi B
Nature communications 2025 Sep 25;16(1):8417

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Macrophage-derived amphiregulin induces myofibroblast transition in adipogenic lineage precursors near Staphylococcus aureus abscess in bone marrow.

Yang B, Su J, Wu J, Wang Z, Hu J, Yang M, Lin Y, Jin M, Bai X, Yu B, Zhang X
Nature communications 2025 Sep 25;16(1):8409

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NCAPH-YAP1 interaction promotes breast cancer stemness and tumor progression.

Qiu C, Wei Y, Li J
Stem cell research & therapy 2025 Sep 25;16(1):494

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Peroxiredoxins as novel indicators in multiple myeloma associated with ferroptosis and immune infiltration.

Chen Y, Peng X, Feng Z, Zhang L, Bai J, Li Y, Li L, Zhang L
Scientific reports 2025 Sep 25;15(1):32765

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Prunella vulgaris seed oil alleviates cancer related fatigue through hypothalamic inflammation and CRH regulation.

Wu C, Hu Q, Han M, Peng Y, Zhang C, Wu Z, Liu R, Xing S, Yin Y, Deli MA, Zhang H, Chen G
NPJ science of food 2025 Sep 24;9(1):194

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Triclabendazole inhibits PKM2 nuclear localization and glycolysis by enhancing HDAC6-mediated deacetylation in lung cancer.

Yan L, Sun Y, Shi SS, Li Y, Zhang YF, Qu LZ, Liu J, Dai Y, Zha QB, Fan J
Journal of translational medicine 2025 Sep 24;23(1):1001

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TAIII Suppresses the Growth of T790M-Mutant Non-Small-Cell Lung Cancer by Targeting the EGFR/ERK Signaling Pathway.

Gao S, Luan Y, Yu X, Wang L, Huang X, Yang J, Liu W
Pharmaceuticals (Basel, Switzerland) 2025 Sep 24;18(10)

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Nuclear FGF2 orchestrates phase separation-mediated rDNA chromatin architecture to control BMSCs cell fate.

Zhang H, Wang Z, Liu Z, Li X, Sun W, Zhen W, Xu F, Wang R, Yin Q, Cao S, Wu M, He J, Xu J, Li Y, Yuan Q
Bone research 2025 Sep 24;13(1):80

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JMJD6-driven epigenetic activation of COL4A2 reprograms glioblastoma vascularization via integrin α1β1-dependent PI3K/MAPK signaling.

Wu Y, Wu Y, Xia S, Lian H, Lou Y, Wang LJ
Acta neuropathologica communications 2025 Sep 24;13(1):194

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GP2a I118 and GP4 D43 play critical roles in the attachment of PRRSV to the CD163 receptor: implications for anti-PRRSV infection targets.

Liu G, Huang X, Yang Y, Chen M, Tian X, Song H, Wang H, Wang S, Wang H, Cai X, An T
Journal of virology 2025 Sep 23;99(9):e0096325

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Dysregulation of PKM2 promotes inflammatory response in allergic rhinitis.

Guo D, Zhou H, Wu X, Xu Y
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Sep 23;74(1):132

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Phosphatidylserine-positive extracellular vesicles for detecting multiple operable cancers.

Jin F, Yang P, Xu R, Zhang S, Li L, Yang L, Bu X, Gao S, Han Y, Ma C, Chen P, Li Z, Zhan S, Liang G, Zhu X, Zhou S, Li X, Li Y, Yang Z, Li X, Wei X, Wang Y
Cell reports 2025 Sep 23;44(9):116259

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Saponin from Tea (Camellia sinensis) Seed Meal Attenuates Cortisol-Induced Lipogenesis and Inflammation in Human Cells.

Li J, Zhang LY, Huang YC, Deng JM, Yu M, Zouboulis CC, Li JH, Wang GL, Wang J
Molecules (Basel, Switzerland) 2025 Sep 23;30(19)

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Identification and prognostic potential of lactylation-related genes in sepsis: implications of the RBM25-acly axis.

Li Y, Zhang T, Zhou L, Huang Y, Li J, Xu H, Wu X
International immunopharmacology 2025 Sep 23;162:115177

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Kaempferol improves mitochondrial homeostasis via mitochondrial dynamics and mitophagy in diabetic kidney disease.

Xia C, Zhang J, Chen H, Jiang W, Zhou S, Zheng H, Sun W
International immunopharmacology 2025 Sep 23;162:115121

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Palmatine ameliorates intestinal epithelial barrier injury in ulcerative colitis via targeting enolase 3.

Zhang Y, Lai Z, Hu X, Wu M, Chen S, Su L, Xie S, Ren M, Yang B, Wang J, Huang W, Su Z, Li Z, Xie Y
International immunopharmacology 2025 Sep 23;162:115110

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Transcriptomic bioinformatics analysis proposes a novel BCL2-MAPK14-TXN oxidative stress diagnostic model of sepsis and identifies TXN as an oxidative stress-related signature gene in sepsis.

Zou Z, Wu M, Peng Y, Luo S
International immunopharmacology 2025 Sep 23;162:115016

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Gut-kidney axis modulation by viable and inactivated Akkermansia muciniphila mitigates avian hyperuricemia through microbial-metabolic crosstalk.

Fu Y, Chen J, Cao Q, Zhu S, Chen W, Luo H, Zhao Y, Bernard LA, Wang X, Tu Q, Zhang Y, Jiang X, Yang L, Wang W
mSystems 2025 Sep 23;10(9):e0077325

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Adipose-derived stem cell exosomes promote neurological recovery after subarachnoid hemorrhage via AMPK/mTOR-mediated TFEB activation.

Liu M, Li S, Wu L, Liu M, Zeng C, Shen J, Cai Z, Yin J, Wu G
Neurological research 2025 Sep 22;:1-12

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Inhibitory Effect of Fucoidan Analogs on Highly Metastatic Gastric Cancer Cells via Galectin-4 Inhibition.

Ji S, Aswathy M, Kuboki Y, Takada Y, Toshima K, Takahashi D, Ideo H
International journal of molecular sciences 2025 Sep 21;26(18)

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Hydrogen Sulfide-Preconditioned Mesenchymal Stem Cells Attenuate Ferroptosis in Corneal Alkali Burn via the AMPK/Nrf2/HO-1 Pathway in an IL-10-Dependent Manner.

Chen M, Jiang Y, Yu H, Qi H, Li X, Wang J, Wang A, Li Z, Wang Q, Huang Y, Wang L
Investigative ophthalmology & visual science 2025 Sep 2;66(12):58

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Kaempferol Alleviates Dry Eye Disease Via Modulation of the IDH3B/CCAR2/IKBKB Axis.

Zhang S, Sha Y, Xie Y, Hong J
Investigative ophthalmology & visual science 2025 Sep 2;66(12):50

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LINC01018 attenuates hepatic lipid accumulation by inducing autophagy via DHX9 pathway in alcohol-associated liver disease.

Ni B, Yang F, Zhao L, Li L, Liang X, Xu R, Xu Y, He Y, Yuan C, Chen W, Zhang Q
International journal of biological macromolecules 2025 Sep 2;328(Pt 1):147298

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Butyric acid and valeric acid attenuate stress-induced ferroptosis and depressive-like behaviors by suppressing hippocampal neuroinflammation.

Ma X, Shi W, Wang Z, Li S, Ma R, Zhu W, Wu L, Feng X, Cong B, Li Y
Journal of translational medicine 2025 Sep 2;23(1):974

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Metal-Organic Framework-Remodeled Gut Microbiota Alleviates Colonic Inflammation via Selective Modulation of Roseburia intestinalis.

Hu H, Su X, Dong Q, Yuan S, Ding S, Liu J, Xu B, Tu L, Liu X, Cao Y, Wang X, Yang G, Guo W, Fu S, Chao D
ACS nano 2025 Sep 2;19(34):31107-31125

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Cholesterol-rich lipid rafts mediate endocytosis as a common pathway for respiratory syncytial virus entry into different host cells.

Zhou A, Xue B, Zhong J, Liu J, Peng R, Wang F, Zhou Y, Tang J, Yang Q, Chen X
Microbiology spectrum 2025 Sep 2;13(9):e0119225

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Curcumin Alleviates HMGB1-Mediated Inflammation Through the Signaling Pathway of TLR2-NF-κB in Bovine Ovarian Granulosa Cells.

Liu S, Xie Y, Wang L, Zhang J, Chen X, Feng X, Wang J, Zhang K, Li J
International journal of molecular sciences 2025 Sep 19;26(18)

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Dovitinib Ameliorates Inflammation-Related Diseases by Inhibiting Necroptosis and Ferroptosis.

Lin Y, Feng J, Zhao M, Zhang L, Li Y, Chen X, Lin C, Lin J, Lin Q, Li J, Wu L, Li L
ACS chemical biology 2025 Sep 19;20(9):2191-2203

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Injectable High-Adhesion Fibrinogen-Silk Fibroin Hydrogel Loaded with Curcumin Accelerates Pterygium Repair via Dual Anti-Inflammatory/Antiproliferative Mechanisms.

Liu J, Liu W, Zhang Y, Ouyang J, Zhao B, Wu C, Li B, Jiang J, Hu K
ACS applied materials & interfaces 2025 Sep 17;17(37):51805-51819

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Pancreatic stellate cells promote pancreatic regeneration in chronic pancreatitis via exosomal lncRNA MALAT1-Induced acinar-ductal metaplasia.

Han D, Wen C, Li J, Xu W, Mo W, Dai W, Xu X, Xu X
Biochemical and biophysical research communications 2025 Sep 16;780:152468

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Mechanism of action of M-XQLD treatment for asthma: role of STARD13 in Th17 suppression.

Ren M, Sun M, Zhang B, Peng M, Song G
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Sep 16;74(1):129

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Inhibition of PERK-eIF2α-ATF4 signaling enhances the antiviral effects of resveratrol-loaded nanoparticles against enterovirus 71 in hand, foot, and mouth disease.

Wang B, Che L, Zhang P, Sun L, Yu Y, Du N
Archives of virology 2025 Sep 16;170(10):207

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STK4 inhibits the E3 activity of HOIP by phosphorylating its allosteric ubiquitin-binding site.

Wang Y, Zhou X, Lin Z, Huang Y, Zhang Y, Liu H, Zhou Y, Liu J, Pan L
Cell discovery 2025 Sep 16;11(1):75

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Study on Antitumor Secondary Metabolites from Euphorbia ebracteolata Hayata: Structural Characterization, Network Pharmacology, Molecular Docking and In Vitro.

Xu NW, Yang YH, Ding L, Cai BX, Li MM, Wang JT, Zheng H, Yu Y
ACS omega 2025 Sep 16;10(36):41479-41491

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Dynamic negative pressure enhances MSC-derived exosomes treatment for vessel injury-related erectile dysfunction by facilitating cavernous diffusion.

Feng C, Li R, Wang G, Liu S, Fu Q
International journal of pharmaceutics 2025 Sep 15;682:125999

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Gremlin 1 regulates granulosa cell apoptosis through the TGF-β/SMAD signaling pathway during bovine follicular atresia.

Xu Y, Liu M, Yang T, Zhao B, Li Y, Wang J, Wang Y, Lin P, Chen H, Wang A, Jin Y, Tang K
Molecular and cellular endocrinology 2025 Sep 15;607:112605

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Decabromodiphenyl ethane induces intrauterine growth restriction by suppressing placental angiogenesis via TWIST2/NAT10-mediated ac4C-dependent TGF-β1 mRNA stabilization.

Ling R, Yin X, Ma L, Zhang Y, Ma Y, Gao R, Geng Y, Mu X, Chen X, Li F, He J
Journal of hazardous materials 2025 Sep 15;496:139377

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ZMAT3 Promotes Liver Regeneration by Regulating P21 mRNA Stability to Modulate Cell Cycle.

Sun L, Zhong H, Huang Z, Wang P, Pu H, Xu T, Ren B, Liu S, Chen H, Fu W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 15;39(17):e70994

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Rufy3 Knockdown Induces PANoptosis Through MAP4/CDK1 Axis to Inhibit Colorectal Cancer Growth: Evidence From In Vitro and In Vivo Models.

Xie R, Yuan W, Chen X, Hao A, Wu Y, Zhang B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 15;39(17):e70988

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Thyroid hormone ameliorates ursodeoxycholic acid-induced heart damage in zebrafish embryos.

Wu H, Wang X, Li H, Li C, Zhu J, Hu J, Zhang C, Zhou X
Life sciences 2025 Sep 15;377:123716

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African swine fever virus pNP419L inhibits type I interferon signaling by blocking ISGF3-mediated transcriptional activation.

Chen Q, Liu L, Wu W, Li L, Yu Z, Liu Q, Wang D, Tan C, Chen H, Wang X
International journal of biological macromolecules 2025 Sep 15;328(Pt 2):147704

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Integrating network pharmacology and experimental validation to decipher the protective effect of icariin against testicular aging.

Sun J, Lv C, Lin Z, Luo S, Liao S, Lian X, Liu Y, Luo L, Zheng M, Zhang D, Wang X, Wang S
Ecotoxicology and environmental safety 2025 Sep 15;303:119063

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Cognitive impairment induced by psychological stress is time-of-day of exposure dependent in female rats.

Wang X, Gao S, Chen L, Zhang L, Liu X, Yin C, Xiao X, Xiong X, Yang J
Brain research 2025 Sep 15;1863:149837

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Rapamycin suppresses small bowel adenocarcinoma HUTU 80 cells proliferation by inhibiting hypoxia-inducible factor-1α mediated metabolic reprogramming.

Pu BP, Wang PH, Guo KK, Liu C, Chen SR, Li XM, Chen SM, Zeng XZ, Gao C
World journal of gastrointestinal oncology 2025 Sep 15;17(9):109378

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Ciprofol attenuates sepsis-induced cardiomyopathy via α7 nicotinic acetylcholine receptor-dependent modulation of myocardial inflammation and NF-κB/STAT3 signaling.

Zhou Q, Zeng X, Kang W, Pan X, Wang L, Xia Z
European journal of pharmacology 2025 Sep 15;1003:177983

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Entospletinib alleviates acute liver injury and acute kidney injury by inhibiting ferroptosis.

Zhao M, Lin Y, Zeng Q, Li Y, Feng J, Chen X, Lin C, Zhang L, Zhong Y, Lin J, Lin Q, Li J, Wu L, Liu X, Li L
European journal of pharmacology 2025 Sep 15;1003:177939

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Lithospermic acid improves diabetic kidney fibrosis by regulating Piezo1/TGF-β1/Smad signaling pathway.

Yan Y, Wang C, Luo S, Hong T, Niu W, Sun X, Zhang E, Yang M, Li Z, Liu J, Zheng Z, Li J
European journal of pharmacology 2025 Sep 15;1003:177896

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Labile iron pool dynamics do not drive ferroptosis potentiation in colorectal cancer cells.

Ponnusamy V, Randall DR, Lee ZH, Das NK, Zhao L, Buscher K, Solanki S, Renslo AR, Hsu PP, Shah YM
bioRxiv : the preprint server for biology 2025 Sep 15;

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HDAC Inhibitors Enhance the Chemosensitivity of Osteosarcoma Cells to Etoposide by Suppressing the Hippo/YAP Signaling Pathway.

Cao Z, Chen Y, Chen M, Fan Q, Sun H, Jin D, Liu Y, Xiong Y, Wang D
International journal of molecular sciences 2025 Sep 13;26(18)

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Lead binds HIF-1α contributing to depression-like behaviour through modulating mitochondria-associated astrocyte ferroptosis.

Shi F, Wang Y, Hao H, Zhao Y, Wu F, Ge Y, Liu SC, Liu P, Wang W, Zhang Y
Communications biology 2025 Sep 11;8(1):1342

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RSL1D1 regulates lung adenocarcinoma progression by inhibiting NRF2 ubiquitination.

Yang Q, Zhang C, Zhang H, Sun S, Zhao G, Yang Q, Huang X, Yan E, Li H, Liu H, Zhang WW
Gene 2025 Sep 10;964:149637

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High-Sucrose Diet-Induced Reprogramming of Plasma Oxylipin Profiles Reflects Dietary Risk for Gut Barrier Dysfunction.

Pan QJ, Yin HH, Liu YN, Dai P, Bai Y, Fu X, Jiang Q, Meng YW, Lin AZ, Zhou X, Huang L, Yin SY, Liu JY
Journal of agricultural and food chemistry 2025 Sep 10;73(36):22407-22424

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PCV2 infection induces the differentiation of Treg cells via the TGF-β/Smad3 pathway.

Jiang R, Huang Q, Shen R, Zhang Y, Zhou L, Ge X, Han J, Guo X, Yang H
mBio 2025 Sep 10;16(9):e0136625

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Metformin limits cerebral cavernous malformation development by targeting KLF4-mediated mitochondrial damage.

Yan C, Ye Y, Liu N, Zhang D, Du W, Li Y, Li G, Li C, Li J, Ma S, Dai Z, Xiong Z, Wang Y, Men C, Bi R, Duan Q, Xu W, Husilengtu, Cao Y, Du J, Shi C
Biochemical and biophysical research communications 2025 Sep 1;777:152241

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The lysosome-associated SLAMF7 inhibits the development of ovarian cancer by promoting lysosomal damage.

Zou W, Fang X, Qian Z, Nie L
Molecular and cellular endocrinology 2025 Sep 1;606:112586

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NudCL2 suppresses pancreatic cancer progression by inhibiting SLC7A11-mediated EMT and metastasis.

Feng J, Yang M, Lin R, Shang K, Sun M, Guo Z, Wang Y, Zhou T, Yang F, Yang Y
Experimental cell research 2025 Sep 1;452(1):114730

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Nitrate Promotes the Survival of Diabetic Skin Flaps by Enhancing Autophagy Through the AMPK Signaling Pathway.

Li M, Zhu L, Xu Y, Han Z
The Journal of craniofacial surgery 2025 Sep 1;36(6):2127-2132

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Melatonin Prevents the Progression of MASLD via Inhibiting FFAs-Induced Ferroptosis through KEAP1/NRF2/HO-1 Pathway.

Li S, Rao P, Yu W, Tang Y, Jiang X, Liu J
Biomolecules & therapeutics 2025 Sep 1;33(5):876-889

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Integrating network toxicology, transcriptomics, and metabolomics uncovers the hepatotoxic mechanisms of okadaic acid in LO2 cells.

Luo Z, Pan F, Fan H, Guo R, Zheng J, Zhang S, Shi J, Lin W, Wang C, Pan Y, Yu G
Ecotoxicology and environmental safety 2025 Sep 1;302:118576

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Rapamycin exerts neuroprotective effects by inhibiting FKBP12 instead of mTORC1 in the mouse model of Parkinson's disease.

Zhang Z, Shen Z, Xie S, Li J, Zhang Z, Zhang S, Peng B, Huang Q, Li M, Ma S, Huang Q
Neuropharmacology 2025 Sep 1;275:110504

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A hydrogel-based drug delivery system reduces inflammation and oxidative stress to alleviate intervertebral disc degeneration.

Wang S, Zhai Y, Liu M, Cheng Z, Zhang J, Zhang H, Wang H, Hu Y, Li C, Luo Z
Acta biomaterialia 2025 Sep 1;203:229-244

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Sodium tanshinone IIA sulfonate alleviates osteoarthritis through targeting SIRT1.

Xu M, Sun X, Ma X, Qin Z, Gao X, Jin X, Sun H
Chinese medicine 2025 Sep 1;20(1):142

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Houttuynia cordata Thunb-derived extracellular vesicle-like particles alleviate ischemic brain injury by miR159a targeting ACSL4 to suppress ferroptosis.

Zhang S, Liang Z, Wu C, Qin Z, Wei X, Liu Y, Su R, Li L, Sun B, Huang L, Wang W, Shen J, Wang G, Qi S
Chinese medicine 2025 Sep 1;20(1):141

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Dietary addition of magnesium hydride nanoparticles: a breakthrough in combating high-fat diet-induced chronic kidney disease.

Lu H, Chen W, Ying Y, Gu D, Li R, Li X, Cheng J, Sun X, Zhang Y, Liu W, Shen H
Medical gas research 2025 Sep 1;15(3):374-382

---

Arbutin improves post-myocardial infarction cardiac dysfunction by inhibiting cardiac fibroblast activation.

Liu Y, Liu X, Zhang X, Yue H, Pan C
Tissue & cell 2025 Oct;96:102986

---

Selenomethionine suppresses lung tumor growth without hepatorenal toxicity in mice via the induction of apoptosis-ferroptosis and angiogenesis inhibition.

Liu H, Zhang C, Zhang L, Shen J, He K, Huang B
Tissue & cell 2025 Oct;96:102956

---

Targeting Ferroptosis Alleviates Pulmonary Arterial Hypertension, Insights from Transcriptomic and Experimental Analyses.

Wang X, Guo Q
Advanced biology 2025 Oct;9(10):e00001

---

Prkcq in ILC2 cells-enhanced the amounts of tissue-resident macrophages promotes pancreatic fibrosis in chronic pancreatitis.

Xiong J, Song J, Jiang X, Huang Z, Zhang Y
Archives of biochemistry and biophysics 2025 Oct;772:110559

---

Astrocytic-HSP60 Depletion Contributed to Autophagy Defects of Astrocytes and Depressive-Like Behaviors in Male Mice.

Li W, Zhu W, Zhu Z, Xie H, Ali T, Yu Z, Li S
Glia 2025 Oct;73(10):2130-2146

---

Porcine GWAS identifies ACOT11 as regulator for macrophage IL-1β maturation via IFNGR2 palmitoylation.

Zhang M, Liu S, Wu Z, Wang C, Zhang H, Yang J, Guo C, Dai M, Wang X, Ren W
Science China. Life sciences 2025 Oct;68(10):3037-3050

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Expression Profile and Prognostic Significance of Pivotal Regulators for N7-Methylguanosine Methylation in Diffuse Large B-Cell Lymphoma.

Wang C, Kong R, Zhong G, Li P, Wang N, Feng G, Ding M, Zhou X
Molecular biotechnology 2025 Oct;67(10):3930-3945

---

PICALM Alzheimer's risk allele causes aberrant lipid droplets in microglia.

Kozlova A, Zhang S, Sudwarts A, Zhang H, Smirnou S, Byeon SK, Thapa C, Sun X, Stephenson K, Zhao X, Jamison B, Ponnusamy M, He X, Schneider JA, Pandey A, Bennett DA, Pang ZP, Sanders AR, Bellen HJ, Thinakaran G, Duan J
Nature 2025 Oct;646(8087):1178-1186

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Long Noncoding RNA MNX1-AS1 Promotes Tumorigenesis of Breast Cancer by Binding IGF2BP1 to Activate c-MET.

Xie J, Gu J, Lv W, Cheng L, Chen S, Wu R, Liang Y, Zhu M, Chen S, Jiang M, Su J
Molecular carcinogenesis 2025 Oct;64(10):1697-1707

---

Ets2 Exacerbates Diabetic Retinopathy by Aggravating the Proliferation of Endothelial Cells and Inflammatory Response.

Wang S, Bao N, Li M, Liu D, Tao L
Biochemical genetics 2025 Oct;63(5):4507-4523

---

Unveiling Moxibustion's Impact on AD Mice Learning and Memory: Role of Mitochondrial Respiratory Chain Complex I Subunit in the Hippocampus.

Shen Y, Li HY, Yang QQ, Zhang K, Liu SQ, Zhang N, Li CY, Yu SG, Xie LS, Wu QF
Molecular neurobiology 2025 Oct;62(10):13413-13429

---

Oropouche virus infection induces pyroptosis in human THP-1 macrophages.

Jurado-Cobena E, Alkan C, Ikegami T
Virology 2025 Oct;611:110630

---

WTAP Silencing protects human aortic smooth muscle cells from angiotensin II-induced senescence, apoptosis, ferroptosis, and inflammation by regulating PCSK9.

Pang H, Fu B, Wang P, Meng Y, Xie P, Hu X, Ma Q
Journal of bioenergetics and biomembranes 2025 Oct;57(4-5):231-244

---

Kirenol relieves rheumatoid arthritis by targeting the TWEAK/Fn14 pathway.

Chen Z, Wang J, Xiao L, Chen Z, Luo W, Xu W, Lin Y, Huang M, Zhang Y, Wang Y, Chen Y, Nan L
International journal of molecular medicine 2025 Oct;56(4)

---

Zinc finger protein 695 facilitates the proliferation of colorectal cancer cells through activation of the NEK2 and PI3K/Akt/mTOR signaling pathways.

Li X, Li X, Wang J, Xue M, Zhang M, Shuai J, Zhang J, Ding D, Wang Y, Hou S, Chi X, Sun H, Gao Q, Kang C
Oncology reports 2025 Oct;54(4)

---

Bioengineered platelet nanoplatform enables renal-targeted dexamethasone delivery for chronic nephritis therapy with dual anti-inflammatory/anti-fibrotic effects and minimized systemic toxicity.

Zhang L, Gong H, Gong X, Zhou B, Wang X, Fei S, Xia D, Xu C, Huang X
Bioactive materials 2025 Oct;52:213-227

---

Specifically Breaking Through the Injured Blood-Brain Barrier With Tannic Acid-Based Nanomedicine for Ischemic Stroke Ischemia Reperfusion Treatment.

Shi X, Wang S, Xiong T, Li R, Zheng W, Chen W, Zhao T, Yang Y, Ying X, Qi W, Xia Y, Wang J, Zhang Y, Huang Q, Nan Y, Ai K
Exploration (Beijing, China) 2025 Oct;5(5):20240388

---

Phosphatidylethanolamine/PKA signal axis mediated human milk extracellular vesicles enhance adipose thermogenesis and lipolysis via mitochondrial remodeling.

Peng Z, Gao J, Xu L, Huang S, Wang R, Du J, Zhang Z, Zhang L, Feng L, Wang X, Guo X
International journal of obesity (2005) 2025 Oct;49(10):2081-2093

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VASP Knockdown Ameliorates Lipopolysaccharide-Induced Acute Lung Injury with Inhibition of M1 Macrophage Polarization Through the cGMP-PKG Signaling Pathway.

Tang J, Ding Y, Chen W, Shi J, Zhang C, Zhao X, Li J, Han Z, Chen X
Inflammation 2025 Oct;48(5):3458-3471

---

4-Octyl Itaconate Attenuates Postmenopausal Osteoporosis by Inhibiting Ferroptosis and Enhancing Osteogenesis via the Nrf2 Pathway.

Li Y, Li Y, Li P, Yang L, Li H
Inflammation 2025 Oct;48(5):3326-3339

---

Inhibition of SLC3A2 Deletion-Mediated Ferroptosis by Bone Marrow Stromal Cells to Alleviate Inflammation and Fibrosis in Diabetic Kidney Disease.

Fan Y, Li YL, Huang LL, Yang J, Hou YY, Bai YH
Inflammation 2025 Oct;48(5):3219-3234

---

4-octyl Itaconate Attenuates Acute Pancreatitis and Associated Lung Injury by Suppressing Ferroptosis in Mice.

Lu S, Gong Y, He P, Qi M, Dong W
Inflammation 2025 Oct;48(5):3156-3168

---

Baicalein Reduces Pyroptosis of Acinar Cells in Hyperlipidemic Acute Pancreatitis by Inhibiting M1 Polarization of Macrophages via the HMGB1/TLR4/NLRP3 Pathway.

Wang X, Zhou Y, Liu Y, Mo T, Chen Z, Zhang Y, Yang L, Liu P
Inflammation 2025 Oct;48(5):3130-3145

---

Kurarinone Mitigates LPS-Induced Inflammatory Osteolysis by Inhibiting Osteoclastogenesis Through the Reduction of ROS Levels and Suppression of the PI3K/AKT Signaling Pathway.

Lv H, Luo H, Tan W, Zhong J, Xiong J, Liu Z, Wu Q, Lin S, Cao K
Inflammation 2025 Oct;48(5):2986-3005

---

Moxibustion Alleviates Inflammation via SIRT5-mediated Post-translational Modification and Macrophage Polarization.

Zuo CY, Zhang CS, Zhang HX, Gou CY, Lei H, Tian FW, Wang ZX, Yin HY, Yu SG
Inflammation 2025 Oct;48(5):2908-2923

---

S100A9 promotes resistance to anti-PD-1 immunotherapy in hepatocellular carcinoma by degrading PARP1 and activating the STAT3/PD-L1 pathway.

Zhou X, Qiao C, Chu X, Yang Y, Man H, Liu J, Li Y, Xu Z, Li H, Shan X, Lian Z, Lu Y, Wang W, Yu D, Sun X, Li B
Cellular oncology (Dordrecht, Netherlands) 2025 Oct;48(5):1433-1447

---

RACK1 attenuates pancreatic tumorigenesis by suppressing acinar-to-ductal metaplasia through inflammatory signaling modulation.

Zhang W, Jiang T, Zhang H, Wei F, Li X, Xie K
Cellular oncology (Dordrecht, Netherlands) 2025 Oct;48(5):1395-1411

---

Collagen type V alpha 3 chain is involved in human skin basement membrane physiology and MMP-9 regulation.

Labarrade F, Garcia I, Imbert I
International journal of cosmetic science 2025 Oct;47(5):743-751

---

Ursolic acid derivative UA312 ameliorates ionizing radiation-induced cardiotoxicity and neurodevelopmental toxicity in zebrafish via targeting chrna3 and grik5.

Xu FF, Shang Y, Wei HQ, Zhang WY, Wang LX, Hu T, Zhang SQ, Li YL, Shang HH, Hou WB, Gou WF, Fan SJ, Li YL
Acta pharmacologica Sinica 2025 Oct;46(10):2677-2692

---

Targeting SPHK1 in macrophages remodels the tumor microenvironment and enhances anti-PD-1 immunotherapy efficacy in colorectal cancer liver metastasis.

Zhan Y, Xu J, Zhang Z, Hu Y, Li Y, Qian J, Ling Y, Wu D, Deng H, Li G, Shen Z, Fang Y
Cancer communications (London, England) 2025 Oct;45(10):1203-1228

---

Speedy A governs non-homologous XY chromosome desynapsis as a unique prerequisite for XY loop-axis organization.

Liu D, Zhang Y, Li D, Jiang B, Zhao X, Li Y, Lin Z, Zhao Y, Hu Z, Deng S, Li Z, Lu H, Chan KKL, Yeung WSB, Kaldis P, Yao C, Wang H, Chow LT, Liu K
The EMBO journal 2025 Oct;44(19):5509-5536

---

Reprogramming Iron Metabolism via the RIG-I/c-Myc/FTH Axis Mitigates Renal Ischemia-Reperfusion Injury.

Zhang Y, Xing J, Yao L, Zou Y, Peng H, Yi X, Bai L, Yu Y, Liu H, Li X, Zhai X
Antioxidants & redox signaling 2025 Oct;43(10-12):622-636

---

African swine fever virus MGF360-9L degrades DDX20 through the Rab1A-dependent autophagy pathway to antagonize its antiviral effect.

He L, Fan X, Zhu Z, Pei D, Wang Y, Li X, Ren Q, Zheng H, Li W, Zhu Z
Virologica Sinica 2025 Oct;40(5):822-834

---

Polydatin protects against leukemia by inducing apoptosis and activating autophagy via p38-MAPK pathway.

Zhang W, Liu Z, Hao P, Zhang P, Pei X, Shi M, Zhu Z
Naunyn-Schmiedeberg's archives of pharmacology 2025 Oct;398(10):13857-13866

---

FGFR1 agonists alleviate pathology and cognitive impairment in an Alzheimer's disease mouse model.

Hung WC, Sun WC, Su TC, Lee YJ, Cheng IH
Experimental neurology 2025 Oct;392:115357

---

Endothelial LRP1 activation mitigates microthrombosis after traumatic brain injury in mice.

Yan R, Wang J, Wu J, Qiu X, Yang L, Yang J, Jiang Y, Peng J
Experimental neurology 2025 Oct;392:115324

---

Hydrogen Sulfide Ameliorates Heart Aging by Downregulating Matrix Metalloproteinase-9.

He K, Zhang H, Tan B, Song C, Liang Z, Zhang L, Tian D, Xiao L, Xue H, Guo Q, Teng X, Jin S, An C, Wu Y
Cardiovascular drugs and therapy 2025 Oct;39(5):967-981

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miR-140-3p Alleviates Pulmonary Arterial Smooth Muscle Cell Dysfunction via MAP2K6/p38 Pathway.

Chen L, Zhang JY, Huang L, Jin LL, Xie WP, Wang H, He MY, Kong H
Journal of biochemical and molecular toxicology 2025 Oct;39(10):e70532

---

Ferroptosis and Lipid Peroxidation Participate in Valproic Acid-Induced Hepatotoxicity via the Long-chain Acyl-CoA Synthetase 4/Glutathione Peroxidase 4 Pathway.

Zhang Y, Li T, Zhang Y, Xu T, Zhao L
Journal of biochemical and molecular toxicology 2025 Oct;39(10):e70484

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Non-Apoptotic Inhibition of Colorectal Cancer Proliferation by Sclareol via Ferroptosis Involving SLC7A11/GPX4 Modulation.

Li YX, Wu Y, Li Q, Huang YQ, Yuan YY, Su YN, Cheng CS, Zheng L
Phytotherapy research : PTR 2025 Oct;39(10):4677-4692

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Combination of imeglimin and resistance exercise improves mitochondrial function and glucose metabolism in skeletal muscles.

Ishiguro H, Minato K, Iwaasa K, Wu S, Antao G, Tsuchida T, Suwabe T, Katagiri T, Suzuki H, Masuko M, Watanabe KI, Ushiki T, Sone H
Journal of diabetes and its complications 2025 Oct;39(10):109145

---

Metal-phenolic encapsulation of carbon monoxide releasing molecule for enhanced gas therapy of periodontitis.

Liu C, Chen Y, Wang Y, Wang D, Sun J, Sun J, Ji L, Li K, Wang W, Zhao W, Song H, Li J
Materials today. Bio 2025 Oct;34:102213

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Neutrophils loaded NAD(+) impede TLR4/NF-κB/NLRP3 pathway for sepsis treatment.

Zhao Y, Qu Y, Huang C, Li C, Zhang W, Wang X, Duan W, He Q, Zhang Y, Jiao J, Zheng R
Materials today. Bio 2025 Oct;34:102168

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Single-cell and spatial transcriptomics identify dihydrolipoic acid succinyltransferase as a promoter of tumor invasion via vascular pathways in cutaneous melanoma.

Gu J, Cheng X, Xu J, Cao H, Liu P, Wang Z, Wu P, Zhang XD, Thorne RF, Wang H, Liu G, Liu X
International journal of biological macromolecules 2025 Oct;327(Pt 2):147504

---

SIRT5 is associated with asthenozoospermia and regulates GC‑2 spd cell proliferation and apoptosis.

Xing H, Chen S, Wang M, Zheng T, Yang B
Molecular medicine reports 2025 Oct;32(4)

---

Panaxadiol acts as an HIF-1α inhibitor to suppress H9N2-induced inflammation.

Xu J, Tao L, Zhang M, Wang S
Veterinary microbiology 2025 Oct;309:110695

---

CYLD suppresses infectious Bursal disease virus replication by deubiquitinating VP1.

Zeng Q, Huang M, Zha B, Huang Y, Fu Q, Chen Z, Wu X, Li X, Chen H, Chen Z, Wu H
Veterinary microbiology 2025 Oct;309:110690

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NR4A1 mediates PRRSV-induced ileal injury in piglets by transcriptional regulation of NLRP3.

Meng F, Zhu C, Zhu C, Yuan L, Li C, Sun M, Cai D
Veterinary microbiology 2025 Oct;309:110677

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GSDME-dependent astrocyte pyroptosis promotes the progression of neuroinflammation in experimental cerebral malaria.

Wang J, Zhu Q, Tong G, Yu K, Liang J, Huang Y, Wang Y, Yang C, Li T, Liang W, Li G, Liu X, Sun J, Li Y, Shen Y, Zhao Y
Apoptosis : an international journal on programmed cell death 2025 Oct;30(9-10):2385-2400

---

Mechanism of action of Aloe vera against human papillomavirus-positive head and neck squamous cell carcinoma.

Zhu K, Han Y, Zhu Y, Zhu X, Huang S, Wang K
Oncology letters 2025 Oct;30(4):475

---

Identification of key ferroptosis-related genes associated with the development of gastric cancer: Prognostic models, molecular mechanisms and potential treatment strategies.

Wang H, Chen H, Liu J, Zhang D, Wang D, Huang M, Li M, He S, Ma L
Oncology letters 2025 Oct;30(4):450

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TRIM16 Inhibits Inflammation by Interacting With and Ubiquitinating TRAF2 in a Colitis Model.

Li DL, Zhou L, Zhang B, Wang S, Liang QY, Liu QH, Qu CJ, Ji L
Journal of cellular and molecular medicine 2025 Oct;29(20):e70917

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Centipede Polypeptide Affects the Inflammatory Reaction and Ferroptosis of Liver Cancer Cells Through the p53/TRAIL Pathway.

Xing X, Lu L, Huang Z, Wang J, Wang L, Hu Y, Yin S, Tian S
Journal of cellular and molecular medicine 2025 Oct;29(19):e70844

---

Molecular signatures of brain glycolysis dysfunction in Alzheimer's disease.

Jia D, Li M, Li L, Wang Q, Zhu XC, Luo J, Yu H
Diabetes, obesity & metabolism 2025 Oct;27(10):5852-5864

---

Design, synthesis and antitumor activity of pentacyclic triterpenoid ursolic acid derivatives and oleanolic acid derivatives based on multi-target.

Ma JJ, Zhang LF, Xu DP, Wang Z, Meng YQ
Journal of Asian natural products research 2025 Oct;27(10):1429-1446

---

TSP50 in Neural Stem Cells Regulates Aging-Related Cognitive Decline and Neuroinflammation by Altering the Gut Microbiota.

Li X, Chen Y, Gao Z, Liu X, Song Z, Gao F, Wang S, Yu C, Sun L, Huang Y, Zheng L, Wang G, Sun Y, Li J, Yang X, Bao Y
Aging cell 2025 Oct;24(10):e70188

---

Bone morphogenetic protein 4 ameliorates corneal neovascularization by inhibiting NLRP3 inflammasome activation through the promotion of CBP-mediated S100A9 acetylation.

Zhang W, Shen S, Nan W, Wu H, Meng C, Guo Q, Wu M, Zhang Y
Free radical biology & medicine 2025 Oct;238:430-449

---

Honokiol protects against heavy-ion radiation-induced oxidative damage via the thioredoxin system.

Chen Y, Shen R, Zhou X, Xu D, Wu Q, Zhang J, Fang J
Free radical biology & medicine 2025 Oct;238:235-245

---

ANG secretion predisposes endothelial cells toward angiogenesis in FIN56-induced ferroptotic hepatocellular carcinoma via the BMP6/ID1 signaling pathway.

Liu X, Long G, Wang Q, Wang J, Chen X, Zhou Y, You K, Li H, Jiang Y, Zhang Z, Du X, Han Y
Free radical biology & medicine 2025 Oct;238:17-35

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FXR overexpression alleviates cholestasis via NLRC4 inflammasome suppression and bile acid homeostasis regulation.

Wang W, Li L, Li X, Chen J, Wang R, Yang Q, Qu Y, Wang C, Fu T, Meng Q
Free radical biology & medicine 2025 Oct;238:152-168

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ZNFX1 functions as a compensatory dsRNA recognition receptor to exert antiviral effect in orange-spotted grouper.

Zheng R, Huang S, Kang Y, Gao J, Wu B, Miao Q, He J, Xie J
PLoS pathogens 2025 Oct;21(10):e1013652

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Retinol binding protein 4 enhances cellular cholesterol uptake to facilitate influenza A virus infection.

Zhao H, Zhang Y, Han Q, Li H, Liu W, Sun L, Shang Y
PLoS pathogens 2025 Oct;21(10):e1013623

---

ATG9 inhibits Rickettsia binding to the host cell surface by blocking the rOmpB-XRCC6/KU70 interaction.

Chen C, Liu G, Xu K, Chen A, Cheng Z, Yan X, Zhang T, Sun Y, Yu T, Wang J, Luo S, Zhou W, Deng S, Liu Y, Yang Y
Autophagy 2025 Oct;21(10):2213-2229

---

Inhibition of PINK1 senses ROS signaling to facilitate neuroblastoma cell pyroptosis.

Zhu Y, Cao M, Tang Y, Liu Y, Wang H, Qi J, Huang C, Yan C, Liu X, Jiang S, Luo Y, Wang S, Zhou B, Xu H, Lu YY, Wang L
Autophagy 2025 Oct;21(10):2091-2110

---

Nuclear ubiquitination permits Hippo-YAP signal for liver development and tumorigenesis.

Wei J, Cao Z, Li Q, Li X, Wang Q, Zhang Y, Zhang R, Wu X, Dai Q, Li X, Zhou Z, Sun F, Jiao S, Zhao B
Nature chemical biology 2025 Oct;21(10):1565-1576

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NSUN5 Mediates Resistance to Doxorubicin via Up-regulation of DNA Damage Repair Proteins BRCA2 and BRIP1 in Colorectal Cancer.

Xu Y, Qin C, Zhang M, Wu Q, Li Z, Mo H, Chen C, Zhou A, Li J, Ni W
The American journal of pathology 2025 Oct;195(10):1921-1935

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Androgen regulates seasonal changes in triglyceride synthesis through the AR-SREBP1-FASN axis in the scented glands of muskrats (Ondatra zibethicus).

Shi X, Gao Q, Lu W, Xie Y, Zhang H, Zhang D, Liu Y, Weng Q
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Oct;1870(7):159675

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Berberine partially ameliorates cardiolipotoxicity in diabetic cardiomyopathy by modulating SIRT3-mediated lipophagy to remodel lipid droplets homeostasis.

Chen W, Jin T, Xie Y, Zhong C, Gao H, Zhang L, Ju J, Cheng T, Li M, Wang H, Yang Z, Deng Q, Du Z, Liang H
British journal of pharmacology 2025 Oct;182(20):5038-5056

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Identification of p38 MAPK inhibition as a neuroprotective strategy for combinatorial SMA therapy.

Carlini MJ, Espinoza-Derout J, Van Alstyne M, Tisdale S, Workman E, Triplett MK, Tattoli I, Yadav S, Henderson CE, Watterson DM, Pellizzoni L
EMBO molecular medicine 2025 Oct;17(10):2762-2786

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Anti-CD24 antibody-nitric oxide donor conjugates bearing a self-bioorthogonal cleavable linker.

Wu J, Cheng T, Xie J, Qian Z, Huang L, Yuan X, Zhang L, Yang S, Zhang Y, Xu T, Zhang J, Huang Z
Acta pharmaceutica Sinica. B 2025 Oct;15(10):5366-5386

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Cannabidiol alleviates methamphetamine addiction via targeting ATP5A1 and modulating the ATP-ADO-A1R signaling pathway.

Jin S, Lin C, Li P, Wang X, Wang Y, Zhang C, Wang X, Peng Y, Li H, Lu Y, Wang X
Acta pharmaceutica Sinica. B 2025 Oct;15(10):5261-5276

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Unlocking the gut-lung axis: Feixin decoction as a novel modulator in hypoxic pulmonary hypertension.

Wang FY, Yi J, Zhou LL, Tan JL, Cao XY, Zhang C, Wan JJ, Song L, Dai AG
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157118

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Removal and toxic intervention of polystyrene microplastics and nanoplastics by magnetic nano-Fe(3)O(4) in spermatogonial GC-1 cells.

Cheng C, Cui Y, Wang Y, Huang J, Ma J, Luo T, Chen W
Reproductive toxicology (Elmsford, N.Y.) 2025 Oct;137:109020

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GALNT6 dual regulates innate immunity STING signaling and PD-L1 expression to promote immune evasion in pancreatic ductal adenocarcinoma.

Chong S, Liu Y, Bian Z, Hu D, Guo S, Dong C, Zeng J, Fan S, Chen X
Cellular signalling 2025 Oct;134:111942

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NCOA4-mediated ferritinophagy promotes pyroptosis by reactive oxygen species generation in the progress of gingival inflammation.

Ren X, Huang Z, Han M, Meng Y, Li H, Li H, Lei L
Cellular signalling 2025 Oct;134:111921

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Acetaldehyde dehydrogenase 1A1 upregulation drives dacomitinib-induced skin toxicity through mitochondrial dysfunction and keratinocyte apoptosis.

Zhou W, Ma X, Tan L, Mei Y, Li H, Chen X, Yang D, Xu G, Yang Y, Wang J, Fang L
Cellular signalling 2025 Oct;134:111913

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Impact of gut microbiome on radiotherapy and immunotherapy efficacy in microsatellite-stable colorectal cancer: role of propionic acid and B. fragilis.

Yu L, Guo Q, Gu X, Wang Z, Li J, Wang X, Xu Z, Wang Y, Zhang Y, Zhang Y, Ding Y, Chen Z, Chen K, Ding Y
British journal of cancer 2025 Oct;133(7):956-969

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Targeting gut microbiota and arginase boosts MEK inhibitors' enhancement of antitumour immunity via MHC-I upregulation in colorectal cancer.

Zhang J, Dong H, Liang L, Hu L, Chen J, Li W, Liu J, Su Y, Shi M, Feng Y, Naccasha EZ, Lewis C, Liu H, Yang X, Wen C
British journal of cancer 2025 Oct;133(6):809-822

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Angiotensin (1-7) decreases the fibrotic process by modulating the TGF-β1/AKT pathway in rat corpus cavernosum smooth muscle cells.

Xu Y, Lu Y, Liu G, Wang C, Tian S, Xiao H, Li W
Sexual medicine 2025 Oct;13(5):qfaf080

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Radioprotective Efficacy of Jujube Aqueous Extract and Arbutin: Synergistic Antioxidant and Anti-Apoptotic Mechanisms in Radiation Injury.

Wang L, Yang H, Zhou X, Zhao Y, Li L, Wang N
Food science & nutrition 2025 Oct;13(10):e71073

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Protective Effects Proanthocyanidin Nanoliposome Freeze-Dried Powder on Oxidative Injury in a p31-43 Induced Celiac Disease Cell Model.

Ning Z, Linlin C, Xing Z, Kunmiao H, Tiantian X, Hanshuo W, Jie S, Miao Y, Hongtao R, Na W
Food science & nutrition 2025 Oct;13(10):e71000

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SORLA Orchestrates microglial dynamics for enhanced neuroprotection and recovery following ischemic stroke.

Ma S, Zhang T, Lv J, Liang S, Zhao S, Nan X, Dou Z, Yang J, Lu Y, Liu R, Li H
Brain, behavior, and immunity 2025 Oct;129:70-86

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Targeting Intratumoral Copper Inhibits Tumor Progression via p62-Mediated EZH2 Degradation and Potentiates Anti-PD-1 Immunotherapy in Oral Squamous Cell Carcinoma.

Lin X, Chen W, Li B, Zhao Z, Yu Z, Zhao XY, Zhou X, Feng Z, Lin C, Cao W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(40):e17795

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Nicotine Reprograms Aging-Related Metabolism and Protects Against Motor Decline in Mice.

Jia S, Jing X, Wang R, Su M, Wang P, Feng Y, Ren X, Tu L, Wei P, Lu Z, Jia Y, Hong F, Mo Z, Zou J, Huang K, Yan C, Zou Q, Wang L, Zhong G, Zeng Z, Yu Q, Su W, Yang X, Pan F, Wang J, Wang L, Kang L, Kenny PJ, Chen Z, Liu XA
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(40):e15311

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ASH2L-K312-Lac Stimulates Angiogenesis in Tumors to Expedite the Malignant Progression of Hepatocellular Carcinoma.

Han H, Wang S, Ma L, Yin H, Cheng X, Wang Y, Xia S, Zhang Y, Zhang Y, Zhu R, Liu C, Zhao D, Gu X, Zhu H, Yuan Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(40):e09477

---

Activation of Lysosomal Retrograde Transport Triggers TPC1-IP3R1 Ca(2+) Crosstalk at Lysosome-ER MCSs Leading to Lethal Depleting of ER Calcium.

Zhu MY, Guo YJ, Zhu YQ, Wang HZ, Wang HD, Chen HY, Jiang YX, Li H, Hui H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(39):e15313

---

Intermediate Filament Protein BFSP2 Controls Spindle Formation via HSC70-Mediated Stabilization of CLTC During Oocyte meiosis.

Li Y, Zhang Z, Zhang Y, Xiong B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(37):e06639

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Epigenetic Regulation of DAPK1 and Netrin-1 Drives Diabetic Encephalopathy.

Zhou Y, Kou JX, Zheng K, Guo ZX, Fan HW, Li WL, Chu LL, Yin JW, Liu LJ, Brazhe N, Xiang ZG, Hu F, Shu K, Zhu LQ, Liu D
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(37):e02535

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HROB Induces Lung Adenocarcinoma Progression via ZC3HC1-CCNB1 Axis Regulation and Cell Cycle Dysregulation.

Zhang Z, Wang C, Guo Y, Zhao Z, Yang Z, Xie S, Hu X, Huang X, Jiang Y, Xiao B, Wang L, Yu F, Wang B
Cancer science 2025 Oct;116(10):2699-2711

---

HSPA4 restrains transferrin in dopaminergic neurons to attenuate ferroptosis in a Parkinson's disease model.

Gao T, Wei H, Ju Q, Lin Y, Yin X, Liu X, Shen J, Ji Q, Sun C, Shen L
Communications biology 2025 Oct 9;8(1):1453

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Translational Research on the Oral Delivery of the Cytotoxic PROTAC Molecule via Tumor-Targeting Prodrug Strategy for Triple-Negative Breast Cancer Treatment.

Hu H, Wang Y, Wang M, Zhang Z, Gu X, Sun R, Liu X, Li N, Ding N, Li W, Zhao X, Li C, Huang Z, Wang X, Li X, Liu S, Yang S, Yang G
Journal of medicinal chemistry 2025 Oct 9;68(19):20464-20486

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Nanovesicles Synergistically Regulate Ferroptosis Characteristic Macrophage-Induced Angiogenesis via Ferritin Heavy Chain 1/Glutathione Peroxidase 4 Pathway to Promote Peripheral Nerve Regeneration.

Huo N, Xu G, Zhou H, Liu Y, Li S, Yang X, Liu J, Wang W, Yang N, Zhou N
ACS applied materials & interfaces 2025 Oct 8;17(40):55876-55894

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TSPAN4 controls vascular smooth muscle cell phenotypic switching and intimal hyperplasia by targeting TPM1-regulated cytoskeletal organization.

Li S, Chen K, Zhang Y, Yu Y, Zhang T, Jiang D, Li M, Fu S, Chen J, Li J, Yi J, Li R, Qiao G, Feng J, Jiang J, Yuan Q, Zhang C
Clinical science (London, England : 1979) 2025 Oct 8;139(19):1145-1161

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Identification of human RNA Polymerase II interactors at early stages of transcription.

Ozer A, Kang JJ, Tang Y, Yugandhar K, Yu S, DeBerardine MD, Omar K, Lis JT, Yu H
bioRxiv : the preprint server for biology 2025 Oct 8;

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cGAS-STING pathway mediates TiO(2) nanoparticle-induced TM4 cell apoptosis via MCUb downregulation and calcium overload.

Li P, Sun C, Wang Q, Hu Y, Song G
Toxicology and applied pharmacology 2025 Oct 7;505:117591

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Fenofibrate alleviates sepsis-associated acute kidney injury by enhancing renal fatty acid oxidation.

Zeng S, Wang J, Guan C, Yao Z, Zhang Y, Li Y, Zheng J, Wang H
BMC pharmacology & toxicology 2025 Oct 7;26(1):160

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ADAP-METTL3 modulates the inflammatory responses of macrophages via m(6)A modification of Spry1.

Dong A, Zhang P, Yang F, Wang Y, Liu H
Cell death & disease 2025 Oct 7;16(1):708

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Transcriptomic Investigation of FoxM1-Mediated Neuroprotection by hAEC-Derived Exosomes in an In Vitro Ischemic Stroke Model.

Wang D, Liu J, Wu L, Yang X, Fang Z, Sun Z, Chen D
Biology 2025 Oct 7;14(10)

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KDM4B modulates ERα signaling pathway to participate in vascular smooth muscle cell calcification.

Liu F, Lv Y, Lin Y, Wang C, Wang S, Zeng K, Zhou B, Lin L, Feng J, Sun G, Chang X, Cao M, Li H, Hu X, Kato S, Zhao Y, Tian W
Cell death discovery 2025 Oct 7;11(1):452

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Targeting ESR1 restores SQSTM1-dependent autophagy and sensitizes ER-positive breast cancer to oxidative and radiation stress.

Yang YF, He ZJ, Kuo HH, Lin YY, Kim CH, Cai HY, Chen CL, Hsiao M, Chen YC, Chang PM, Chang YC
Cell death discovery 2025 Oct 7;11(1):451

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ILF3 downregulation by circMETTL9: Effect on traumatic brain injury-induced neuroinflammation.

Sun L, Huang H, Hu Y, Guan Y, Zhu J, Xiao C, Zhang ZJ, Liu S
Experimental neurology 2025 Oct 6;395:115490

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PARL stabilizes mitochondrial BCL-2 via Nur77-mediated scaffolding as a therapeutic strategy for Parkinson's disease.

Yin S, Zhai Y, Song R, Wu J, Zhang Y, Yu M, Ma H, Shen M, Lai X, Jin W, Xu Y, Yan J
Cell death & disease 2025 Oct 6;16(1):700

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Acetylation-dependent USP7-TRIM25 axis drives oncogenic progression in non-small cell lung cancer.

Yang J, Chen Z, Hu W, Zeng W, Lei Z, Tong X, Li Q, Luo G, Hu K, Chen Z, Liu Z, Li C, Xu C, Ding C, Zhang HT, Zhao J
Cell death & disease 2025 Oct 6;16(1):695

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TGR5 dysfunction underlies chronic social defeat stress via cAMP/PKA signaling pathway in the hippocampus.

Chen X, Zhou Q, He Y, Wang Y, Jiang Y, Ren Y, Ren Y, Cai J, Yu H, Chen C, Cheng K, Xie P
Translational psychiatry 2025 Oct 6;15(1):366

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Macrophage NLRP3 activation and IL-1β release drive osimertinib-induced antitumor immunity.

Yu H, Sun X, Li Y, Pan J, Liu X, He H, Wu H, Sun Y, Pan Y, Qian X
Journal for immunotherapy of cancer 2025 Oct 5;13(10)

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PM(2.5) enhances DRP1-mediated mitochondrial fission to induce ferroptosis and exacerbate asthma through the AHR-HSP90-PKM2 pathway.

Qiao S, Li F, Huang J, Wu X, Cao X, Zhang X, Wei Z
Toxicology and applied pharmacology 2025 Oct 4;505:117590

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α-L-fucosidase isoenzymes (FUCA1/FUCA2) as prognostic markers in gliomas: a comprehensive study.

Zuo C, Liu Y, Wang Z, Chen H, Wang Y, Qiao Y
BMC cancer 2025 Oct 4;25(1):1511

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Harpagide Confers Protection Against Acute Lung Injury Through Multi-Omics Dissection of Immune-Microenvironmental Crosstalk and Convergent Therapeutic Mechanisms.

Wang H, Yang J, Zhang Y, Wang J, Song S, Gao L, Liu M, Chen Z, Li X
Pharmaceuticals (Basel, Switzerland) 2025 Oct 4;18(10)

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Melatonin Activates AMPK Pathway to Regulate the Regeneration of Slow Muscle Fibers in Skeletal Muscle Injury Repair.

Xie W, Hong Z, Xie Y, Hou K, Li S, Fang M, Guan Y, Zhang Z, Zhang M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Oct 31;39(20):e71123

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Wuhu decoction regulates ROS/AMPK/mTOR pathway-mediated dendritic cells autophagy and pyroptosis for the treatment of respiratory syncytial virus-induced asthma.

Ding Y, Luo J, Deng YJ, Liu JL, Wang MQ, Hu Y
Journal of thoracic disease 2025 Oct 31;17(10):7810-7825

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Protective effects of estradiol on neuroinflammation in chronic obstructive pulmonary disease related depression.

Lu J, Li Y, Zhang Z, Xu J, Zhang G, Luo X, Zheng H, Lu W, Huang Q
Journal of thoracic disease 2025 Oct 31;17(10):7673-7688

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LSM4 as a potential prognostic indicator and therapeutic target in triple-negative breast cancer progression.

Ren Z, Li Y, Yang X, Zhang N, Wang F, He Z
Gland surgery 2025 Oct 31;14(10):1990-2004

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FUT8 promotes HDM-induced glycolysis, epithelial-mesenchymal transition and inflammation in bronchial epithelial cells by inducing N-glycosylation modification of GLUT1.

Huang W, Yuan X, Lu J, Zhang S, Sun Y, Hang Y, Shen Y, Chen M, Li J, Huang J, Zhang W, Li L
Biochemical and biophysical research communications 2025 Oct 30;786:152721

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MDA-9/Syntenin promotes glioma cell proliferation and invasion via exosome-mediated activation of the PI3K-AKT signaling pathway.

Zheng Y, Yu X, Zhong Z, Li M
Biochemical and biophysical research communications 2025 Oct 30;786:152720

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Microwave dynamic therapy induces ferroptosis in colorectal cancer by targeting PTK2B to regulate STAT3-mediated GPX4 expression.

Zhou H, Zhang Z, Liu Z, Xiong L, Ran X, Liu J, Ran Y, Wen Y, Chen W, Xu J
Molecular biomedicine 2025 Oct 30;6(1):91

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Yiqi Wenyang Formula ameliorates diabetic kidney disease via inhibiting inflammation and regulating the gut microbiota-bile acid axis in mice by FXR signaling pathway.

Yuan T, Gao X, Wang X, Tang X, Liang Z, Yin Y, Liu S, Ou J, Su W, Zhang Z, Li X, Huang Q, Zhao D, Zhang H
Chinese medicine 2025 Oct 30;20(1):183

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PGRN mediates the crosstalk between ovarian cancer cells and CAFs and reshapes tumor immune microenvironment.

Ning X, Wang Y, Zhai L, Gao W, Jin Z, Iqbal H, Ur-Rehman U, Gao L, Lv M, Yuan Z, Yi Z, Wang B, Chen W, Ma R, Xiao R
International immunopharmacology 2025 Oct 30;164:115362

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SIRT5 induces glomerular sclerosis in diabetic nephropathy through p53.

Liu S, Xu Z, Li X, Zhang Y, Cai Z, Yin X, Wang J
International immunopharmacology 2025 Oct 30;164:115352

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MYCN-mediated pyroptosis and inflammation in the molecular mechanism of MicroRNA-202-3P promote functional recovery in spinal cord injury.

Fang J, Huang K, Zhang G, Shi B, Bi H, Shuai L
International immunopharmacology 2025 Oct 30;164:115349

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Increased peripheral CD4(+) lymphocytes promote ketamine-induced abnormal behaviors in mice.

Hu J, Wang P, Lin Y, Jiang Z, Zhang Y, Shi K, Wen D, Ma C, Liao L, Wang X
International immunopharmacology 2025 Oct 30;164:115337

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Rutin alleviates preoperative anxiety stress-induced persistent postoperative pain by inhibiting microglia-mediated abnormal synaptic engulfment in the spinal cord dorsal horn.

Zhang Y, Yang H, Zhao Y, Ni K, Sun J, Ma Z
International immunopharmacology 2025 Oct 30;164:115309

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Taurodeoxycholic, taurocholic, and glycocholic acids promote hepatic gluconeogenesis via TGR5 in dairy cows.

Zhu M, Zheng Y, Lou S, Zhang R, Feng D, Lei X, Chen L, Wang J, Yao J, Deng L
Journal of animal science and biotechnology 2025 Oct 30;16(1):142

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Reactive Oxygen Species (ROS) Drive Osteocyte Dysfunction in Diabetic Osteoporosis by Impairing Autophagy and Triggering Apoptosis.

Han M, Zhao M, Bai F, Wang M, Zhang B, Shi J, Liu Z
Antioxidants (Basel, Switzerland) 2025 Oct 30;14(11)

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Protein Disulfide Isomerase A3, a Stress Response Gene, Is Associated with Cognitive Impairment in Schizophrenia and Linked to Inflammatory Activation.

Su X, Fan X, Li J, Li R, Liu J, Yang Y, Song M, Shao M, Han Y, Liu Q, Zhang L, Wang C, Lv L, Li W
Schizophrenia bulletin 2025 Oct 30;

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Mitochondrial ClpX Inhibition Induces Ferroptosis and Blocks Pancreatic Cancer Cell Proliferation.

Wang P, Zhang R, Pan Y, Wu W, Zhang T, Yang CG
Chembiochem : a European journal of chemical biology 2025 Oct 3;26(19):e202500551

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Multiomics Insights into the Mechanism and Enhanced Efficacy of Tumor Treating Fields (TTFields) Therapy in Glioblastoma.

Gao Y, Wang C, Liu G, Zhang R, Ren X, Hu G, Mei Q, Huang H
Journal of proteome research 2025 Oct 3;24(10):5056-5070

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Poliumoside Alleviates Neuroinflammation and Oxidative Stress After Spinal Cord Injury by Activating the PI3K/AKT/mTOR Signaling Pathway.

Li Q, Hong H, Xu G, Xia M, Wang T, Zhou Z, Huang J, Fu Q, Cui Z
Journal of integrative neuroscience 2025 Oct 29;24(10):43900

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Diabetes exacerbates myasthenia gravis by enhancing pathological thymic output via the GPR183-7α,25-OHC axis.

Dong J, Shi X, Gu XD, Yang Y, He YL, Zhou Y, Li H, Du T, Si WY, Wei SL, Liu C, Yang B, Li YB, Duan RS, Yang CL, Zhang P
Journal of neuroinflammation 2025 Oct 29;22(1):250

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Integrated Multi-Omics Analysis Identifies SRI as a Critical Target Promoting Gastric Cancer Progression and Associated with Poor Prognosis.

Gong Z, Wang W, He Y, Zhou J, Yang Q, Feng A, Huang Z, Pan J, Li Y, Yuan X, Ma M
Cancers 2025 Oct 29;17(21)

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Novel magnolol-sulforaphane hybrids as potent antitumor agents: synthesis and biological characterization.

Peng Y, Liu B, Guo Y, Chen J, Chen H, Liu X, Huang J, Luo D, Hong Y, Wu D, Chen Z, Lin X, Tao C
RSC medicinal chemistry 2025 Oct 29;16(12):6380-96

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IRG1 catalyzed energy metabolite itaconic acid restrains type I interferon-dependent immune responses by alkylation of TBK1.

Chai L, Li C, Wang X, Qin Y, Sun H, Du J, Yang L, Hu D, Xiong J, Zhao Z, Gong R, Wu T, Wu M, Nie M, Gao J, Jia J, Gao C, Zhao W, Zhou H, Kang D, Jia M
Cell reports 2025 Oct 28;44(10):116336

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Mutant RIT1 cooperates with YAP to drive an EMT-like lung cancer state.

Rominger MC, O'Brien S, Gupta S, Moorthi S, McSharry M, Kamlapurkar S, Lowe AR, Waldum A, Lo A, Duke F, Wu F, Headley MB, Cromwell E, Glabman R, Koehne A, Berger AH
Cell reports 2025 Oct 28;44(10):116185

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Comprehensive Proteomics Profiling Reveals Biomarkers of Oxidative Stress and Membrane Integrity in Red Blood Cells in Acute Altitude Sickness.

Li S, Wang Y, Zhou W, Wang Y, Zhang Z, Wu Z, Tu B, Xiao C, Liu D, Yan J, Ma Z, Gao Y
ACS omega 2025 Oct 28;10(42):49870-49886

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Study of plasma exosomal miRNAs as novel biomarkers for differentiating primary central nervous system lymphoma and glioblastoma.

Lu S, Xu L, Lan Y, Wang C, Mo L, Yan H
BMC cancer 2025 Oct 27;25(1):1657

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Translation of nervous necrosis virus involves eIF4E but not RPS6 phosphorylation and viral particle assembly in remodeled microtubule-organizing center.

Bajpai V, Li CH, Lai CS, Fang KY, Chiang MH, Chen WD, Chen WY, Chen CW, Wang YS, Chen SC, Cheng CA, Chang CY
Virology journal 2025 Oct 27;22(1):341

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Giant grouper nervous necrosis virus subgenomic RNA3 is transcribed by a premature termination mechanism via intragenomic RNA-RNA pairing.

Cheng CA, Lai CS, Liao FE, Yeh SL, Chiang MH, Li CH, Fang KY, Liao YC, Hsu HC, Bajpai V, Chi CK, Chen CW, Liu HW, Chang CC, Chang CY
Virology journal 2025 Oct 27;22(1):340

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Systems Pharmacology and Multi-Omics Elucidation of Irpex lacteus Polysaccharides in the Treatment of Lupus Nephritis Through PI3K/AKT/NF-κB Pathway Inhibition.

Ji G, Yao Z, Zhao Y, Li C, Yang B, Li Z, Kuang M, Wang H, Wu X, Yuan H, Deng Y, Wang S, Wang H
Pharmaceuticals (Basel, Switzerland) 2025 Oct 27;18(11)

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Aronia melanocarpa anthocyanins attenuate light-induced retinal damage by enhancing photoreceptor cell function and anti-inflammatory effects.

Ye M, Zuo L, Li X, Sun D, Xu X, Huang S, Bai W
Food & function 2025 Oct 27;16(21):8496-8514

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Novel anti-LAG-3 antibody LBL-007 with anti-PD-1 blockade enhances antitumor immunity by promoting T cell-induced apoptosis.

Qin K, Zhou H, Yu X, Liu J, Wu C, Zhang C, Zhou L
Scientific reports 2025 Oct 27;15(1):37515

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Structural basis for transport and inhibition of the human glucose-6-phosphate transporter G6PT.

Xia Z, Wang Y, Wu D, Chi C, Li C, Chen L, Jiang D
Nature communications 2025 Oct 24;16(1):9420

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HMGB-1 Increases Proinflammatory Reaction via TLR4 in Human Granulosa Cells of Endometriosis.

Kim HI, Kim KH, Cho S, Choi YS, Lee BS, Chon SJ, Yun BH
Journal of clinical medicine 2025 Oct 24;14(21)

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Identifying a novel region in the Tembusu virus NS5 protein antagonizing type I interferon signaling.

Zhang J, Fan Y, An D, Mao M, Guo Z, Yang J, Li Q, Zhu S, Li G, Chen X, Zhou Z, Hou S, Diao Y, Tang Y
Journal of virology 2025 Oct 23;99(10):e0131025

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Oropouche virus NSs protein suppresses host transcription by targeting the RNA polymerase II RPB1 protein.

Jurado-Cobena E, Alkan C, Ikegami T
Journal of virology 2025 Oct 23;99(10):e0117625

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HIV proviral transcription and infectivity are enhanced by neddylation.

Vaca CC, Hudson H, Clerc I, Song C, D'Aquila RT
Journal of virology 2025 Oct 23;99(10):e0096825

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The WW domain presents a promising target for the development of PCIF1 agonists in the treatment of glioma.

Yin J, Liu G, Zhou Y, Zhou J, Guo M, Hu Z, Musunuru PP, Yu R, Meng Q, Gao S
NPJ precision oncology 2025 Oct 23;9(1):329

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Discovery of dCDK9-202 as a Highly Potent and Selective PROTAC CDK9 Degrader with Strong In Vivo Antitumor Activity.

Ma L, Xie L, Wang Y, Guan X, Zhang Y, Guo H, Zhou J, Liu J, Huang X, He C, Chen Y, Xu L, Han X
Journal of medicinal chemistry 2025 Oct 23;68(20):21172-21186

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Inhibition of glutamine synthetase enhances hepatocellular carcinoma radiosensitivity through ROS-induced excessive mitophagy.

Liu R, Ju G, Lu Y, Liu X, Ding Q, Wang K, Gu H, Qian J
Molecular biology reports 2025 Oct 23;53(1):5

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Ershen Dan attenuates atherosclerosis by modulating the NOTCH1/NF-κB/NLRP3 signaling pathway to suppress M1 macrophage polarization.

Zhao W, Wang H, Peng S, Wei Q, Zhang L, Li Y, Yang W
Chinese medicine 2025 Oct 23;20(1):178

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Targeted degradation of endogenous YAP by nanobody bioPROTAC inhibits tumor progression.

Zhou R, Wang H, Zhang GM, Liu Y, Liu XL, Li Z, Shi G, Yuan J, Qu C, Li Y, Chen L, Huang J, Zhou H, Dai L, Bai C, Wang J, Yu L, Li Z, Li YL
Nature communications 2025 Oct 23;16(1):9374

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Piezo1 exacerbates psoriasis by promoting macrophage M1 polarization and inhibits autophagy via activating PI3K/AKT signaling pathway.

Liu X, Du S, Jiang Y, Chen Y
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Oct 22;74(1):149

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Long-pulsed 1064-nm neodymium: yttrium-aluminum-garnet laser alleviates rosacea by improving lymphatic vessel dysfunction.

Gu D, Pan R, Liu T, Meng X, Ye Q, Hong C, Sun C, Wang Y, Yang W, Chen N, Liu W, Xu Y
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Oct 22;74(1):147

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TAK-242 inhibits toll-like receptor-4 signaling and attenuates cancer-associated muscle atrophy via the p38-C/EBPβ pathway.

You Y, Su Z, Wang H, Liu S, Wang J, Qiu F, Jiang Z, Wang J, Li Y, Zhang G
Journal of molecular histology 2025 Oct 22;56(6):347

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IGFBP2-Ceramide Pathway Mediates Divergent Myelin Breakdown in the PNS and CNS Following Injury.

Ma S, Fu X, Lyu J, Guo W, Wang J, Li J, Ying Z
The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 Oct 22;45(43)

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A novel non-nad-based PARP1 inhibitor, Japoflavone B, triggered Caspase-3/GSDME-mediated pyroptosis through ROS/p38/p53 pathway in NSCLC.

Wan H, Wei J, Wang Y, Ge L, Hu Q, Li Y, Zhou B, Zeng X
Chemico-biological interactions 2025 Oct 22;420:111693

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METTL3-mediated modification of SIRT1 m6A methylation protects osteoblasts from TBHP-induced senescence and promotes osteoblast proliferation.

Chen Y, Wang Y, Xiao H, Teng F, Yang A, Liu J, Liu Z, Sheng X, Zhang C, Zhang S, Geng B, Xia Y
Chemico-biological interactions 2025 Oct 22;420:111672

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Gut symbiont-derived ursodeoxycholic acid promotes fatty acid oxidation to protect against renal ischemia-reperfusion injury.

Xie M, Zheng J, Yu Y, Yang Q, Zhou Z, Xue J, Wang B, Qiu Y, Zhu Z, Sun Q, Shi X, Shangguan W, Li L, Zou Z, Zhao J, Wu P
Cell reports. Medicine 2025 Oct 21;6(10):102373

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Vorapaxar enhanced mitochondria-associated ferroptosis primes cancer immunotherapy via targeting FOXO1/HMOX1 axis.

Zhou Q, Sun Y, Du S, Dian Y, Yao L, Su H, Guo Z, Meng Y, Xiong Y, Deng Z, Kuang X, Liang X, Liu H, Deng G, Chen X, Zeng F
Cell reports. Medicine 2025 Oct 21;6(10):102371

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CRLS1 influences liver metastasis in colon cancer by regulating lipid metabolism pathways.

Mu J, Li D, Shen H, Cao M, Zhang L, Wang C, Sun K, Wang H, He Y, Liu K, Huang X, Liang Q, Tang W, Kong X
Functional & integrative genomics 2025 Oct 21;25(1):216

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Bridging metabolism and immuno-inflammation: a novel framework to characterize dilated cardiomyopathy subtype.

Yu C, Liu C, Liu B, Feng J, Deng Y, Yuan J
Journal of translational medicine 2025 Oct 21;23(1):1145

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A Therapeutic System Regulating Iron Metabolism in CD63(+) Macrophage Subsets Activates Anti-tumor Immunity for Bone Metastasis Therapy.

Xue Y, Wang S, Yin Y, Chai X, Zhou Z, Li H, Mou H, Wang F, Yao M, Zhao S, Lei J, Jin L, Fang M, Chen F, Li Z, Sun Y, Xu Y, Li H, Xu J, Zhang N
ACS nano 2025 Oct 21;19(41):36544-36565

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PTPN2 acts as a tumor suppressor and therapeutic target in ovarian cancer.

Sun X, Zhang W, Wang H, Hao J, Shi W, Lei P, Wei G, Liu Y, Xu C, Li L, Yu L, Zhang DL
Biochemical and biophysical research communications 2025 Oct 20;785:152704

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DNAJC5 promotes cisplatin resistance in epithelial ovarian cancer by autophagy induced by the BiP/IRE1α/XBP1 endoplasmic reticulum stress pathway.

Huang S, Chen L, Chen Y, Lu S, Yang B, Chen Y, Zhao W, Zhao S
Scientific reports 2025 Oct 2;15(1):34323

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DnaJB1 chaperone inhibits tau aggregation by recognizing its N-terminus.

Wydorski PM, Macierzynska P, Bali S, Vaquer-Alicea J, Joachimiak LA
bioRxiv : the preprint server for biology 2025 Oct 2;

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Modeling Alzheimer's Disease with APOE4 Neuron-Glial Brain Assembloids Reveals IGFBPs as Therapeutic Targets.

Sherman E, Qiu K, Roberts R, Shichman L, Li S, Sun H, Ide L, Tucker A, Lee S, Gniadzik W, Shin JB, Sol-Church K, Kapur J, Zhang A, Erisir A, Jiang L, Alzheimer’s Disease Neuroimaging Initiative
bioRxiv : the preprint server for biology 2025 Oct 19;

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Downregulation of Nrf2 deteriorates cognitive impairment in APP/PS1 mice by inhibiting mitochondrial biogenesis through the PPARγ/PGC1α signaling pathway.

Luo W, Bu W, Zhang G, Dong Y, Wang Y, Wang J, Liu C, Hu X, Jia Y, Ren H
Behavioural brain research 2025 Oct 18;495:115805

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Cetacean loss of the master adipose tissue regulator β(3)-adrenergic receptor may underlie their thick blubber and an Oligocene radiation and dispersal.

Tian R, Zhang T, Dong H, Seim I, Yang G
Nature communications 2025 Oct 17;16(1):9235

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Corynebacterium pseudotuberculosis phospholipase D targets mitochondrial sphingomyelin and induces NLRP3-GSDMD axis-mediated pyroptosis in macrophages to promote infection.

Li X, Lv H, Wu C, Li H, Yi W, Niu X, Peng Q, Meng C, Yuan Y, Tian S, Wang Z, Fang R, Zhou Z
Veterinary research 2025 Oct 16;56(1):198

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Proanthocyanidins carbon dots inhibit PRRSV infection by activating Nrf2/ARE to regulate oxidative stress and NLRP3 inflammasome-mediated pyroptosis.

Wang F, Pan Z, Amona FM, Chen X, Pang Y, Liang Y, Lai M, Zhang C, Chen X, Fang X
Veterinary research 2025 Oct 16;56(1):197

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Tert-Butylhydroquinone (TBHQ) Suppresses LPS- and Poly (I:C)-Induced RAW 264.7 Macrophage Activation Through Reduced NF-κB/Type 1 Interferon and Enhanced Antioxidant-Related Pathways.

Whisel AM, Rice CD
Toxics 2025 Oct 16;13(10)

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Microcystin-LR facilitates pubertal bone retardation by interfering with glutamine metabolism to accelerate stem cell senescence through Hippo/GLS pathway.

Pan C, Liu T, Fan Z, Ma B, Wang K, Wang X, Zhang Y, Hong R, Chen H
Environmental pollution (Barking, Essex : 1987) 2025 Oct 15;383:126931

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Nitrite and microcystins co-exposure triggers PINK1-mediated mitophagy in spermatogonia.

Wang F, Fu Y, Liu H, Du X, Meng R, Ge K, Liang X, Yang J, Wang X, Guo F, Guo H, Zhang H
Ecotoxicology and environmental safety 2025 Oct 15;305:119239

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Nuclear receptor Nr1d1 links sleep deprivation to intestinal homeostasis via microbiota-derived taurine.

Wang Z, Zhou L, Zheng Y, Zhong X, Huang R, Sun W, Wang S, Li W
Journal of translational medicine 2025 Oct 15;23(1):1106

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Lactylation-induced ALKBH5 targets RNF123 to worsen retinal Müller cell activation through PKM2-regulated Glycolysis in diabetic retinopathy.

Luo S, Sun Y, Hu Y, Xu Y
Journal of translational medicine 2025 Oct 15;23(1):1105

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Exosomal transfer of miR-375-3p from pancreatic β cells to hepatocytes impairs hepatic glycogenesis via Rbpj repression.

Xu FZ, Dou L, Wu X, Xia CX, Yu DN, Man Y, Shen T, Huang XQ
World journal of diabetes 2025 Oct 15;16(10):109815

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Axon guidance cue SLIT2 regulates the murine skeletal stem cell niche through sympathetic innervation.

Wu Z, Li N, Luo Z, Chen Z, He X, Han J, Lin X, Shi F, Huang H, Shi B, Li Y, Wang X, Meng L, Zhang D, Chen L, Zhou D, Cheng W, Greenblatt MB, Xu R
The Journal of clinical investigation 2025 Oct 15;135(20)

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HSP90 inhibition induces oncogenic EGF receptor degradation to suppress cell growth in non-small cell lung cancer.

Zhu Y, Wang P, Li Y, Wang J, Wang L, Cheng S, Zhang Y, Yang Y, Song J, Zhang Y, Liu S, Dai Z
European journal of pharmacology 2025 Oct 15;1005:178105

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Hydrogen promoted mitochondrial autophagy and alleviated CIH-induced vascular endothelial cell senescence by regulating oxidative stress.

Li D, Liu Q, Fan X, Qi K, Sun M, Song J, Guo Y, Ji E
European journal of pharmacology 2025 Oct 15;1005:178078

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Inhibition of tumor cell macropinocytosis driver DHODH reverses immunosuppression and overcomes anti-PD1 resistance.

Wang Y, Chai Y, Liu Y, Liu X, Zhang Y, Yang Z, Yin S, Luo J, Li Z, Gu Y, Yu Y, Cao X
Immunity 2025 Oct 14;58(10):2456-2471.e6

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Gasdermin C cleavage by Cathepsin S modulates Rab7 vesicles in intestinal epithelial cells to amplify anti-helminth immunity.

Pandey SP, Yang D, Hedden L, Laughlin CR, Wang W, Soto AS, Winner H, Medina Sanchez L, Campana EE, Engl C, Zeng Y, Rana M, Van Der Kraak L, Bender MJ, Prokopec J, Ferrick JM, Meng X, Fong E, Sun M, Mullett SJ, MacDonald M, Gelhaus SL, Watkins SC, Meisel M, von Moltke J, Xu S, Gong YN, Hinterleitner R
Immunity 2025 Oct 14;58(10):2439-2455.e8

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Fermentation of Panax ginseng C.A. Meyer extract with lactic acid bacteria exerts hepatoprotective effects via activating the NRF2 pathway.

Liang JJ, Liu HX, Yan JG, Xie G, Liu WL, Lin JH, Li XM, Mao XL
Journal of molecular histology 2025 Oct 14;56(6):343

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The Sirt3-CD38 axis induces mitochondrial dysfunction in hypertrophied heart by regulating mitochondrial calcium overload.

Liu J, Liu N, Qi C, Dong D, Liu B
European journal of medical research 2025 Oct 14;30(1):967

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Construction of a lipid metabolism-based prognostic gene signature in cervical squamous cell carcinoma and validation of LIPG's oncogenic role.

Bai G, Chen F, Qiu J, Hua K
Cancer cell international 2025 Oct 14;25(1):349

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Mitochondrial ribosomal protein L12 mediates metabolic reorganization in clear cell renal cell carcinoma by regulating mitochondrial biosynthesis.

Sun S, Su D, Dong T, Wang B, Ji X, Chu L, Lu S, Zhang T, Sun X, Liu Y, Wan Q
Cell communication and signaling : CCS 2025 Oct 14;23(1):435

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Nano-Self-Assembled Particles Loaded with Aldehyde Dehydrogenase 2 Agonist Inhibit Ischemia-Reperfusion Injury of Transplanted Kidneys.

Hu Q, Lu Z, Yasen K, Liu A, Shi X, Ye Q, Zhong Z
ACS nano 2025 Oct 14;19(40):35853-35870

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Comparative Transcriptomics Analyses Identify DDX43 as a Cellular Regulator Involved in Suppressing HSV-2 Replication.

Cheng R, Li Y, Chen Y, Zhang M, Hu Q, Liu Y
Viruses 2025 Oct 13;17(10)

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Malate targets pyruvate kinase M2 to promote colorectal cancer cell cycle arrest and tumor suppression.

Zhao K, Zhang F, Qin Q, Zhang D, Yang F, Huang Y, Deng R, Jing H, Xiao W, Miao H, Shi R
Molecular biomedicine 2025 Oct 11;6(1):79

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Multi-omics analysis of polyamine metabolism implicates NT5E/CD73 in the progression of pancreatic cancer.

Zhang E, Ding X, Zhang J, Liu W, Liu G, Li M, Liu X, Wang Y, Zhang F, Li B, Zhu Y, Yan Y, Liu J, Wang Y, Tian X, Ma Y, Yang Y
Cancer letters 2025 Oct 10;630:217887

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Targeting JAK2 with a multifunctional nanoinhibitor for long-lasting anti-inflammatory effects and bone repair.

Liu Y, Wang D, Zheng W, Wang Y, Wang P, Zhao Y, Liu X, Shi Y, Wang Y, Zhou N, González FE, Sun H, Zhou D, Xu X
Journal of nanobiotechnology 2025 Oct 10;23(1):649

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Neuroprotective effects of Berberine-loaded BMSCs-apoptotic extracellular vesicles on retinal ganglion cells: therapeutic potential for glaucomatous injury.

You M, Zhang X, Zeng Z, Xiang S, Chen J, Xie S, Ma X, Chen S, Xia X
Journal of nanobiotechnology 2025 Oct 10;23(1):646

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Plasmodium yoelii infection regulates M1 macrophage polarization and function through TLR7/STAT3 signaling pathway.

Mo L, Jiang Z, Hong C, Guo J, Qiu G, Wu Q, Deng G, Chen Y, Lu Y, Zhou H, Liu Q, Luo X, Zhao Y, Qi Y, Li Q, Ma X, Yang Q
International immunopharmacology 2025 Oct 10;163:115311

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METTL3-mediated MSRB3 m6A modification accelerates hypoxia-induced cardiomyocyte ferroptosis by inhibiting mitochondrial oxidative phosphorylation.

Li Y, Xia J, Wei Y, He M, He G, Zhu Y
International immunopharmacology 2025 Oct 10;163:115268

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SZ168 alleviates bleomycin-induced pulmonary fibrosis by inhibiting podoplanin-induced platelet activation.

Gao X, Chen YX, Wu S, Deng ZH, Wei XY, Zhang GX, Zhao YM, Qian JX
International immunopharmacology 2025 Oct 10;163:115244

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Long noncoding RNA ENST00000458139 promotes mitochondrial dysfunction and apoptosis of podocytes in diabetic kidney disease through binding with SNRPA1.

Yang M, Fan X, Lang Y, Hu J, Wang Q, Shen N, Zhang D, Chai S, Wang R, Lv Z
International immunopharmacology 2025 Oct 10;163:115232

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GDF15 attenuates sepsis-induced acute lung injury by suppressing the HIF-1α/LDHA pathway.

Kuang X, Niu Z, Huang Z, Cai X, Wang L, Zhang Y, Luo J, Zhao X, Shuo L, Zhang P
International immunopharmacology 2025 Oct 10;163:115198

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Actomyosin forces trigger a conformational change in desmoplakin within desmosomes.

Dong Y, Elgerbi A, Xie B, Han Y, Kwiatkowski AV, Choy JS, Sivasankar S
Nature communications 2025 Oct 10;16(1):9052

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Molecular bases of the interactions of ATG16L1 with FIP200 and ATG8 family proteins.

Gong X, Zhou Y, Wang Y, Tang Y, Liu H, Zhou X, Zhang Y, Guo H, Guo Z, Pan L
Nature communications 2025 Oct 10;16(1):9035

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Fosaprepitant Dimeglumine Alleviates Dengue Virus Infection and Virus-Induced Inflammatory Responses.

Deng X, Zheng N, Liu S, Cao W, Li YP, Zhang G
ACS infectious diseases 2025 Oct 10;11(10):2814-2820

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Rv2647-Mediated NLRP3 Ubiquitination Inhibits Macrophage Pyroptosis and Promotes Mycobacterium tuberculosis Survival.

Jin X, Yan H, Chen X, Feng J, Li G, Yao J, Du X, Feng G
ACS infectious diseases 2025 Oct 10;11(10):2739-2753

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Diazepam-induced locomotor sensitization and increased cell surface AMPA receptors: Involvement of GABA(A) α1 subunit.

Yang T, Chen Y, Di B
European journal of pharmacology 2025 Oct 10;:178212

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Glutathione contributes to alleviating hepatic injury via host-microbiome interaction and CAR-dependent pathway.

Xiang X, Liu S, Wang H, Wang C, Zhou W, Chen H, Feng Y, He X, Xu G, Zhao Q, Li T, Liu D, Yin Y, He L
Science China. Life sciences 2025 Oct 10;

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SPP1 exacerbates ischemic stroke by promoting ferroptosis induced brain injury.

Zhou Y, Zhang L, Yan X, Yang Z, Kou Z, Jiang L, Zhu W, Song J, Li J
Biochemical and biophysical research communications 2025 Oct 1;783:152627

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Succinate-mediated Ufsp2 transcription promotes high glucose-stimulated pyroptosis in rat retinal Müller cells by activating NLRP3 inflammasome.

Zhao S, Zhang Y, Li C, Zheng Z, Ma M
Biochemical and biophysical research communications 2025 Oct 1;783:152614

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Development of Two In Vitro ND1-LHON Models for Evaluating Gene Therapy Efficacy.

Li X, Yuan J, Chen Z, Zhang Y, Liu Y, Zhang Y
Investigative ophthalmology & visual science 2025 Oct 1;66(13):34

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CircFGFR2 induces astrocyte pyroptosis to promote ischemic stroke.

Pang N, Liu Y, Yu S, Li Y, Shi K
Neuroscience 2025 Oct 1;584:356-366

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Suppressor of Tumorigenicity 14 inhibits non-small cell lung cancer cell proliferation by suppressing Transketolase O-GlcNAcylation.

Ji L, Zhang M, Liu Y, Zhang H, Luo T, Zhao L, Zhang W, Chen B, Chen R
Experimental cell research 2025 Oct 1;452(2):114776

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Mitochondrial DNA-driven senescence-associated secretory phenotype promotes the development of bronchopulmonary dysplasia.

Meng Y, Shi H, Xu H, Sun Y, Wang X, Wang R, Zhang Y
American journal of physiology. Cell physiology 2025 Oct 1;329(4):C1332-C1342

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Mechanism of silica nanoparticles induced pulmonary epithelial-mesenchymal transition mediated by exosomal HNRNPAB.

Zhao X, Pan Y, Yan G, Yu Y, Song Y
Ecotoxicology and environmental safety 2025 Oct 1;304:119162

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Mangiferin targets PFKFB3 to inhibit glioblastoma progression by suppressing glycolysis and PI3K/AKT/mTOR signaling.

Xia J, Li X, Yao J, Song D, Gu Z, Zheng G, Tu C
Brain research bulletin 2025 Oct 1;230:111520

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Activation of SIRT3 / PRDX5 signaling inhibits apoptosis after acute spinal cord injury in mice.

Ni H, Sha W, Xu T, Zhu Q, Huang Q, Wang J, Gu Q, Zhu Y, Wang L, Tian S, Gao R, Ge J, Lin X
Brain research bulletin 2025 Oct 1;230:111510

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Sevoflurane-induced cognitive dysfunction in aged mice mediated by HDAC8-dependent suppression of adult hippocampal neurogenesis via the pCREB/BDNF pathway.

He Y, Guo Y, Li X, Wu J, Feng Z, Wang G, Zhang M
Brain research bulletin 2025 Oct 1;230:111497

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Loss of histone methyltransferase Smyd3 triggers WAT browning and adaptive thermogenesis via enhancing PPARγ expression in a H4K20me3-dependent manner.

Shu M, Ma Y, Zhao D, Meng C, Chen L, Wang L, Liu J, Yang D
Journal of translational medicine 2025 Oct 1;23(1):1041

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Sishen pill alleviates ulcerative colitis via the NLRP3/ASC/Caspase-1 signaling pathway: Comprehensive validation through UPLC-Q-TOF/MS, network pharmacology, molecular docking, and in vivo experiments.

Luo Q, Long H, Guo C, Wei X, Wang X, Zhang H, Luo S, Liu Z, Liu J, Zhou S, Lin X
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2025 Oct 1;1264:124735

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Sigma-1 receptor counteracts non-cell-autonomous poly-PR-induced astrocytic oxidative stress in C9orf72 ALS.

Wu HC, Huang TW, Weng EF, Lin CY, Su TP, Wu HE, Wang SM
Redox biology 2025 Nov;87:103875

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Molecular mechanism of the crosstalk between glucocorticoid receptor (GR) and hypoxia-inducible factor 3α (HIF-3α) pathways.

Zhang M, Guo Y, Diao X, Guo M, Teng H, Sun X, Zhuang J, Song C, Xie X, Wu D
Marine life science & technology 2025 Nov;7(4):779-791

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Ellagic Acid and Its Nanoparticles Mitigate Atherosclerosis by Elevating Low-Density Lipoprotein Receptor Levels Through Targeting of the Epidermal Growth Factor Receptor.

Li GT, Wang LT, Yin HL, Zhao SQ, Sheng J, Huang YW, Wang XJ
FASEB bioAdvances 2025 Nov;7(11):e70069

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Saccharomyces boulardii Alleviates Ovalbumin-Induced Pyroptosis Through Cyba and IL-17 Signaling Pathway.

Chen Z, Hu L, Yang Y, Wang Y, Li Y, Su J, Wang G, Gong S
Molecular nutrition & food research 2025 Nov;69(21):e70194

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Harnessing TP73‑targeted nintedanib: A novel strategy to halt triple‑negative breast cancer via p53‑PPARα/PI3K‑Akt pathway suppression.

Zou X, Li S, Huang S, Niu R, Liu G, Wang Z
International journal of oncology 2025 Nov;67(5)

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Implication of GPRASP2 in the Proliferation and Hair Cell-Forming of Cochlear Supporting Cells.

Cai J, Huang K, Li W, Wang T, Yue S, Chen Z, Xing G, Wei Q, Yao J, Cao X
Cell proliferation 2025 Nov;58(11):e13792

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Mitochondrial dysfunction-associated cellular senescence is partially involved in bleomycin-induced pulmonary fibrosis in mice.

Yao YX, Lu X, Li Z, Liao HY, Liu ZB, Zhao H, Wang H, Xu DX, Tan ZX
Toxicology and applied pharmacology 2025 Nov;504:117524

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S100A11 mediates the protective effects of edaravone dexborneol on docetaxel-induced cognitive impairment in rats by inhibiting the MAPK signaling pathway.

Liu P, Jia J, Lu Y, Tang H, Gao C, Han S
Toxicology and applied pharmacology 2025 Nov;504:117504

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Li-Ginseng powder protects against alcohol-induced liver injury by promoting acetaldehyde clearance and cellular homeostasis.

Wang YN, Wang DY, Li YH, He CY, Li XM, Li Y, Jin YH
Journal of ginseng research 2025 Nov;49(6):758-766

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Targeting PPARα activation sensitizes glioblastoma cells to temozolomide and reverses acquired resistance by inhibiting H3K18 lactylation.

Wang ZC, Li C, Zhang Z, Lu S, Liu YM, Qi P, Chen X, Wang YB, Feng WJ, Pan CL, Wang QX, Ji ZL, Yu Y, Piao MH, Chi GF, Ge PF
Acta pharmacologica Sinica 2025 Nov;46(11):3071-3086

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NDUFA8 promotes cell viability and inhibits ferroptosis and cisplatin sensitivity by stabilizing Fe-S clusters in cervical cancer.

Xiang H, Sun J, Kong L, Wang Y, Qiu X, Zeng J, Li G, He J
Naunyn-Schmiedeberg's archives of pharmacology 2025 Nov;398(11):15547-15559

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Urolithin A improves Parkinson's disease-associated cognitive impairment through modulation of neuroinflammation and neuroplasticity.

Xu N, Du C, Yu Y, Li Y, Gao S, Yu S, Sun B, Lou H
Experimental neurology 2025 Nov;393:115395

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Quercetin Targets HSP90α and Regulates Keap1/Nrf2 Pathway to Inhibit Crosstalk between Apoptosis and Ferroptosis in Oxidatively Stressed Neurons.

Liu J, Zhang ZZ, Yu GR, Han X
Journal of biochemical and molecular toxicology 2025 Nov;39(11):e70583

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Formosanin C Induces ROS/p38-Mediated Cell Death While Also Promoting Protective Autophagy in Pancreatic Cancer.

Chen D, Wen Z, Huang G, Ruan Q, Wen C, Qi J, Zhuang Q, Xie N, Yang X, Deng J
Phytotherapy research : PTR 2025 Nov;39(11):5302-5315

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Icariside II Ameliorates Depression Induced by High-Fat Diet via the Microbiota-Gut-Brain Axis in Mice.

Luo YM, Dong L, Li YL, Lin M, Xie DY, Gao JM, Zhang YD, Zhu YZ, Gong QH
Phytotherapy research : PTR 2025 Nov;39(11):5159-5173

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CLIC1 regulates cellular oxidative stress and gastric cancer progress by enhancing ACOX1 ubiquitination.

Li C, Yang J, Huang W, Wang S, Feng Y, Chen T, Xu W, Chen J
International journal of biological macromolecules 2025 Nov;330(Pt 4):148292

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Autophagic damage in senescent bone marrow mesenchymal stromal cells: Impact on Piezo1 expression during osteoporosis progression.

Huang C, Chen X, Wu D, Chen J, Wang J, Li S, Hu J, Yan Z, Zhu Y, Zhang Y
International journal of biological macromolecules 2025 Nov;330(Pt 1):147928

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Characterization of Periplaneta americana glycoproteins' structures and their potential to treat immunological liver fibrosis.

Li K, Yang X, Chen Z, He R, Wan J, Yang Y, Shi G, Xiao P
International journal of biological macromolecules 2025 Nov;329(Pt 2):147900

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Elevated FBXL6 activates ATAD3A through K63-linked polyubiquitination and promotes the malignant progression of TNBC via metabolic reprogramming.

Wu Y, Pan J, Wei J, Wang Z, Chen Q, Li M, Qian X, Pan Y, Yu H
International journal of biological macromolecules 2025 Nov;329(Pt 2):147713

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A High-Fat Diet Damages the Blood-Testis Barrier Through the PCSK9-LOX1 Positive Feedback Loop in Sertoli Cells.

Zhang G, Wang Z, He M, Kong L, Yushanjiang S, Jin L, Zhao R, Ma Z, Pan Y, Hu Y, Nie L, Yuan D
Reproductive sciences (Thousand Oaks, Calif.) 2025 Nov;32(11):3587-3598

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eIF1 and eIF5 dynamically control translation start site fidelity.

Grosely R, Alvarado C, Ivanov IP, Nicholson OB, Puglisi JD, Dever TE, Lapointe CP
Nature structural & molecular biology 2025 Nov;32(11):2308-2318

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NLRX1 mediated impaired microglial phagocytosis of NETs in cerebral ischemia and reperfusion injury.

Peng J, Huang Y, He T, Zhan Y, Liu J
Cell death and differentiation 2025 Nov;32(11):2160-2174

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Interferon Regulatory Factor1 Deficiency Ameliorates Hemorrhagic Shock-Induced Kidney Injury Via IGFBP7/IGF1R Pathway.

Cai J, Zhang J, Wang N, Wang Y, Jia D, Ge X
The Journal of surgical research 2025 Nov;315:515-525

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Bovine coronavirus Nsp14 protein promotes viral replication by degrading TRAF3 to inhibit interferon production.

Sun H, Liu Y, Yang X, Qin W, Lu X, Wang Y, Tong W, Yu H, Zheng H, Tong G, Shan T, Kong N
Veterinary microbiology 2025 Nov;310:110708

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Tetramethylpyrazine alleviates acute kidney injury by activating the Wnt/β-catenin pathway independent of DKK1.

Wang X, Chang X, Yang D, Zhang L, Guo Z, Sun X, Li A, Ni Y, Du P
Experimental and therapeutic medicine 2025 Nov;30(5):208

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Study on the anticancer mechanism of hydroxygenkwanin in esophageal cancer via the ESRRA signaling pathway.

Wang Y, Xin Wan L, Zhang Y, Jia Q, Li C, Cui X
Cancer genetics 2025 Nov;298-299:180-192

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The Network of Exosomes miRNA and p-MLC2 Regulatory Pathway Induced Pathological Cardiac Hypertrophy in Vasn Deficient Mice.

Huang B, Li Q, Yin S, Zhang J, Guo X, Yu N, Hu B, Li L, Huang Q, He M, Sun J
Journal of cellular and molecular medicine 2025 Nov;29(22):e70929

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CXCL1 Promotes Osteoblast Autophagy and Inhibits Ferroptosis Through the Activation of the TGF-β/Smad Signalling Pathway.

Zhou Z, Wang Y, Gao Z, Chen Q, Wu H, Sun J, Li H, Liu D, Shen Y
Journal of cellular and molecular medicine 2025 Nov;29(21):e70883

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Integrin β5-positive cancer-associated fibroblasts promoting lung adenocarcinoma invasion leading to poor prognosis.

Shibata S, Inoue C, Miki Y, Notsuda H, Niikawa H, Okada Y, Suzuki T
Pathology, research and practice 2025 Nov;275:156215

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The integrated treatment of photodynamic therapy and oncolytic Virotherapy: A dual-modal paradigm for breast Cancer.

Li Y, Wang K, Min Q, Lu H, Zhang G, Yan J
Journal of photochemistry and photobiology. B, Biology 2025 Nov;272:113248

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Astragaloside IV: a natural shield against ochratoxin A-induced hepatotoxicity in chicks by targeting the NRF2/NLRP3 signaling pathway.

Yang J, Xu H, Ye R, Zhang Y, Wu J, Jin E, Li X, Cao M, Li S, Liu C, Li L
Toxicon : official journal of the International Society on Toxinology 2025 Nov;266:108513

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Targeting LARP1 to mitigate aging in lens epithelial cells: mechanistic insights into mitochondrial dysfunction.

Qi H, Sun L, Chai J, Ma J, Yu H, Xia M, Hu X
Experimental eye research 2025 Nov;260:110582

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Fabrication of Lithium/Strontium-Releasing Smart Bioactive Glasses with Anti-Inflammatory and Osteogenic Effects Tailored to Pathological Stages.

Sakai H, Sasaki JI, Kitagawa H, Abe GL, Kohno T, Funayama N, Imazato S
Macromolecular bioscience 2025 Nov;25(11):e00268

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Early maternal separation potentiates the impact of later social isolation in inducing depressive-like behavior via oxidative stress in adult rats.

Chen Y, Du J, Lei M, Ji N, Zhang W, Li C, Zhang B
Psychopharmacology 2025 Nov;242(11):2503-2515

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Iron supplementation protects against renal ischemia-reperfusion injury by enhancing mitochondrial respiratory complex assembly.

Qi Y, Wang Z, Zhang Z, Yan Y, Cheng F, Feng Y, Hou Y, Zhu H, Li Z, Xu Z, Feng X, Feng G, Shang W
Biochemical pharmacology 2025 Nov;241:117197

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Pitavastatin overcomes multi-drug resistance in CRC and NSCLC by targeting the NRP1-ZFX axis.

Zhai YY, Wang Q, Nong QY, Gao MY, Zhang Y, Xiao QW, Tian Y, Zhang ZJ, Xu FG, Zhang P
Biochemical pharmacology 2025 Nov;241:117183

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Adaptively increased intake of arginine sustains oral keratinocyte survival through alleviating oxidative stress during targeting glutamine metabolism.

Lv C, He H, Lin M, Li W, Mu W, Cheng B, Tao X
Biochemical pharmacology 2025 Nov;241:117165

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A novel PARP-ATR dual inhibitor exhibits anti-triple-negative breast cancer activity by inducing excessive DNA damage in the mitotic phase.

Wang CC, Duan J, Mao ND, He M, Zhang PP, Yuan Y, Gao Y, He X, Shao X, Wang S, Hui Z, Zhang H, Ko BCB, Ye XY
Biochemical pharmacology 2025 Nov;241:117160

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BDH2 promotes GLIPR1 promoter methylation and thus increases 5-FU sensitivity in colorectal cancer.

Lu D, Ma L, Zhang Q, Xing C, Li Y
Biochemical pharmacology 2025 Nov;241:117153

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Rhein suppresses osteosarcoma progression via modulating the miR-328-3p/TCF7L2/FABP4 axis.

Zhao X, Wang R, Xia X, Han C, Wei W, Zhao W, Ji R, Zhang L
Biochemical pharmacology 2025 Nov;241:117152

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Neutrophil extravasation and NETosis in decompression illness lung injury: A P-selectin/PSGL-1/NOX2/PAD4 axis governed pathway validated by multi-model interrogation.

Li Z, Wang S, Bai Y, Liu S, Huang J, You Y, Li J, Yu X, Han Y, Bao X
Free radical biology & medicine 2025 Nov;239:14-26

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Deferoxamine attenuates sepsis-induced liver injury by suppressing ferroptosis.

Zhang H, Li H, Liu S, Zheng J, Li P
Immunobiology 2025 Nov;230(6):153125

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The RNA-binding protein RBM39 scaffolds an m⁶A-dependent RNA decay complex that destabilizes Tat transcripts and restricts HIV-1 reactivation.

Deng X, Xie S, Zhou M, Yuan Q, Wu S, Huang P, Chen M, Zeng J, Guo P, Qin J, Chen C, Liu J, Liu B, He X, Sun L, Zhang H, Li L, Pan T
PLoS biology 2025 Nov;23(11):e3003486

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Network Pharmacology and In Vitro Experiments Reveal the Mechanism of Agaricus blazei Murill Extract in Treating Chronic Myeloid Leukemia.

Wang D, Zhu H, Ge W, Sun Y
Chemistry & biodiversity 2025 Nov;22(11):e00758

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A Shikonin Derivative Induces Excessive Autophagy in Pancreatic Cancer Cells.

Cao Q, Zhou Y, Xiong L, Sheng M, Peng Y, Huang J, Zhang S
Chemistry & biodiversity 2025 Nov;22(11):e00721

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Downregulated miR-199a-3p in Preeclamptic Placenta-derived Exosomes from Cord Blood Hinders VEGF-induced Fetal Glomerular Dysplasia Through Inhibiting Akt1(S473) Phosphorylation via Targeting PHLPP2.

Jiang X, Gu M, Xie Y, Li Y, Lv Q, Chen P, Jing D, Zhou Y, Wang X, Li L
Stem cell reviews and reports 2025 Nov;21(8):2693-2710

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Mass spectrometry and enzyme assays refute histone tyrosine sulfation.

Youssef MM, Szot CW, Ayad MF, Hussein LA, Abdel-Ghany MF, Bailey RC, Mostafa AM, Hakansson K
Nature chemical biology 2025 Nov;21(11):1667-1670

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Electrical Vagus Nerve Stimulation Ameliorates Cardiac Ischemia and Reperfusion Injury by Improving Mitochondrial Biogenesis Through the SIRT1/PGC-1α Pathway.

Guo Y, Zhang Y, Zhang J, Bai X, Kang W, Guo Y, Zeng X
Applied biochemistry and biotechnology 2025 Nov;197(11):7314-7336

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Overinhibition mediated by parvalbumin interneurons in the medial prefrontal cortex might contribute to LPS-induced depression-like behavior in mice.

Shi C, Fan D, Liu K, Hu X, Gao Y, Liu QR, Wu X, Ji M
Journal of psychiatric research 2025 Nov;191:417-429

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Transcranial direct current stimulation attenuates cerebral ischemia-reperfusion injury by inhibiting neuronal pyroptosis via Netrin-1.

Wang Y, Liu H, Li P, Zhang Z, He Y, Chen Y, Peng Y, Wang B, Jiang L, Li C, Zhu Q, Niu L
Neurochemistry international 2025 Nov;190:106041

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Heterozygous Kctd5 knockout mice exhibit abnormal lipid metabolism.

Ling Q, Cao M, Zhang HA, Li X, Wang W, Wang Z, Sun Q, Liang Z, Huang W, Wang M, Li X, Lin C, Jiang X, Pan JA, Peng X
The international journal of biochemistry & cell biology 2025 Nov;188:106851

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Identification and validation of BCL11A as a neural and immune vulnerability factor in pancreatic adenocarcinoma.

Chen A, Wang J, Yang J, Wang Y, Wu C, Yang H, Fan Y, Gao Q, Hu Y, Li X, Zou X
Biochimica et biophysica acta. Molecular basis of disease 2025 Nov;1871(8):167988

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Inhibition of spreading depolarizations by targeting GABA(A) receptors and voltage-gated sodium channels improves neurological deficits in rats with traumatic brain injury.

Yan R, Liu Q, Zhang D, Li K, Li Y, Nie Y, Zhang Y, Li P, Mao S, Li H
British journal of pharmacology 2025 Nov;182(21):5247-5268

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Age-Dependent Amino Acid Metabolism.

You C, Long X, Wei H, Lu Y, Guo X, Wang S, Sun Z
The Journal of nutrition 2025 Nov;155(11):3791-3808

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Fufang Huangqi Jianpi Oral Liquid alleviates spleen deficiency diarrhea via modulation of the NF-κB/Nrf2 signaling pathway and apoptosis.

Huang L, Qiu Z, Sun K, Yu C, Huang Q, Liu C, Pan X, Li S, Ge S, Shi X, Hu F, Xin R
3 Biotech 2025 Nov;15(11):377

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Rosmarinic acid induces ferroptosis in colon cancer: insights from AKR1C3/PTGS2 pathway and mitochondrial dysfunction.

Tang J, Zhang J, Chen H, Wang Z, Wu L, Xue P, Yang R, Peng W, Zeng P
3 Biotech 2025 Nov;15(11):374

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Celastrol ameliorates metabolic dysfunction associated steatohepatitis by regulating the CYP7B1-mediated alternative bile acid synthetic pathway.

Hu M, Yang J, Chen Y, Zhang Y, Liu CH, Feng Y, Ye B, Li D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157172

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Huaier overcomes tumor-induced immunosuppression in colorectal cancer by activating MHC I and CD8+ T cells.

Chen J, Li Y, Sun Q, Wang Y, Qiu Z, He X, Zhong X, Chen F, Huang H, Chen K, Zhu Y, Yao Y, Hu Z, Wang X, Tang J, Zhao S, Wei P, Li D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157157

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Formononetin, a bioactive isoflavone compound in modified nuanxinkang, alleviates cardiorenal syndrome type 4-induced mitochondrial dysfunction by targeting Hippo-YAP signaling.

Yao M, Wen R, Zhuang H, Li Y, Lin X, Pang S, Zhang J, Guan Z, Liang B, Li H, Huang Y, Wang L, Wang J, Dong X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157152

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Benzoylpaeoniflorin alleviates ulcerative colitis by inhibiting ferroptosis through targeting phosphogluconic dehydrogenase.

Tang Y, Wang Z, Zhou F, Li L, Sun C, Li L, Tang F, Huang D, Li Z, Tan Y, Pei G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157111

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Theaflavin-3,3'-digallate prevents alcoholic liver injury by suppressing hepatic TLR4/NF-κB signaling and modulating the gut-liver axis in mice.

Tang MG, Xiong LG, Huang JA, Hara Y, Zhang S, Liu ZH, Liu AL
The Journal of nutritional biochemistry 2025 Nov;145:110031

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Calcitriol/Vitamin D receptor ameliorates fructose-induced enteritis-hepatitis axis dysregulation in mice.

Yu J, Zhu H, Yu X, Liu Y, Zhang J, Jiang L, Zhang X
The Journal of nutritional biochemistry 2025 Nov;145:110017

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RBM39 silence suppresses esophageal cancer proliferation and metastasis via FANCD2 mRNA destabilization.

Yang X, Li C, Zhang C, Zhang L, Wei W, Ji M, Jiang B
Cellular signalling 2025 Nov;135:112047

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Enhanced 5-methylcytosine methylation of PSD4 facilitates vasculogenic mimicry in breast cancer brain metastases through ferroptotic resistance.

Li M, Cui C, Li J, Zhou J, Chen S, Yan J, Zhang D, Zhang Y, Xie P, Yao Y, Ni F, An M, Zhang W, Fu B
Cellular signalling 2025 Nov;135:112022

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Ferroptosis promotes sepsis-related lung injury via endothelial cell senescence.

Yao Y, Wang S, Shi W, Yang L, Tian Y, Wang D, Xia D
Cellular signalling 2025 Nov;135:112018

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Cannabidiol attenuates diet-induced metabolic endotoxemia, neuroinflammation, and anxiety-like behaviors in male aged rats.

Jantsch J, Rodrigues FDS, Wickert F, Fraga GF, Dias VS, Bitencourt YM, Giovenardi M, Guedes RP
Brain, behavior, and immunity 2025 Nov;130:106121

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Epigallocatechin-3-Gallate Mitigates Atopic Dermatitis-Like Skin Lesions and Psychiatric Comorbidities by Reducing Oxidative Stress.

Tang L, Peng R, Guo J, Wang C, Wang T, Bao Y, He Y
Food science & nutrition 2025 Nov;13(11):e71248

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Clonorchis sinensis Crude Antigen Suppresses Osteoclast Differentiation via Modulation of the NF-κB and MAPK Signaling Pathway.

Tang L, He S, Ma B, Tang Z, Zhan T, Xiao S, Wang J, Zhao J, Xu J, Shi Y
Immunity, inflammation and disease 2025 Nov;13(11):e70292

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Significance of integrated clinical and proteomic characteristics analysis for pathogenesis and management of Crohn's disease with concomitant psoriasis.

Zhang H, He C, Fan X, Song Q, Lin C, Zhou P, Song Y, Li N, Shi Y, Lin Z, Chen Q, Zheng Y, Wang S, Li Z, Zhang W, Liu Q, Qing Q, Sun Y, Huang B, Li M
EBioMedicine 2025 Nov;121:105981

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RAB26 promotes prostate cancer progression via the MAPK/ERK-TWIST1 signaling axis.

Wang H, Liang S, Du X, Zhao G, Bai Y, Li J, Xu H, Peng S, Yuan Y, Tang W
Genes & diseases 2025 Nov;12(6):101689

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XBP1s Mediates Cross-resistance to Combination Treatment of CDK4/6 Inhibitors plus Endocrine Therapy in Breast Cancer.

Sang Y, Liu S, Zhou X, Chi W, Xiong M, Chen M, Ren H, Liu D, Zhang L, Xue J, Chi Y, Wu J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(44):e09588

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A Single-Molecule Pleuripotent Scaffold for Combinational Therapy of Alzheimer's Disease via Intranasal Administration.

Gao JM, Li WB, Chen NN, Yi Y, Wang ZH, Chen X, Zhao YY, Yuan ZL, Gao J, Pan YC, Guo DS, Gong QH
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(43):e11611

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Engineering Neutrophil Vesicles for Synergistic Protection against Ischemia/Reperfusion Injury after Lung Transplant.

Yuan HX, Ye YY, Shen P, Zhang J, Meng QF, Chen Y, Xu X, Zhang XL, Rao L, Fan ZJ, He JX
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(42):e06127

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Resident Macrophage-Orchestrated Immune and Fibroblast Interactions in Immune Checkpoint Inhibitor-Associated Nephrotoxicity.

Ma Y, Chen Y, Yao Q, Wang Y, Ouyang N, Han F, Wang G, Wang M, Yuan Y, Chen J, Shan J, Chen D
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(42):e05445

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Deficiency of Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 in Pancreas Reduces β Cell Mass.

Luo C, Feng Y, Min J, Zhao Y, Zhu Z, Sun L, Yin H, Yin Y, Zhang W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(41):e08858

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The Composite Antiadhesion Barrier Facilitated Fibroblast Autophagy Activation for Tendon Repair.

Sun Z, Liu J, Chen L, Wang Z, Wang F, Liu S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(41):e06204

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The NSP5, ORF6 and NSP13 of SARS-CoV-2 Cooperate to Modulate Inflammatory Cell Death Activation.

Wang H, Liang M, Zhang J, Tong H, Zhang F, Liu Y, Wang P, Chang M, Han F, Liu S, Lin Y, Song W, Karki R, Wang P, Chen H, Liu Y, Zheng M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(41):e03977

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Super-enhancer-driven ELOVL5 promotes T-ALL progression through the MYC-SERBP1 pathway.

Zhang S, Cheng W, Li T, Zhang Z, Yu J, Jiao W, Wan X, Wu Y, Xu L, Ji T, Yang Y, Pan J, Lu J
Genomics 2025 Nov;117(6):111111

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Hypoglycemic effect and the post-treatment benefits of carrot pulp fermented by Lactobacillus casei NCU215 in type 2 diabetic mice: insights from gut microbiota regulation and restoration of pancreatic islet function.

Kang X, Xiong T, Yazhou X, Chen Y, Ruan Y, Guan Q
Journal of the science of food and agriculture 2025 Nov;105(14):7826-7839

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Effect of berberine on LPS-induced intestinal epithelial injury and m(6)A methylation in broilers.

Yuan L, Li W, Li G, Jin W, Wang B, Li S, Wang H
Poultry science 2025 Nov;104(11):105677

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Hydrogen activated the Nrf2/HO pathway to alleviate the cognitive decline in PD Drosophila after long-term sevoflurane exposure.

Li M, Ma B, Liang S, Pan X, Xie J, Wang H, Guo J
Neurotoxicology and teratology 2025 Nov-Dec;112:107560

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Loss of Dmrta1 alters CD8+ T cell activation and resistance to influenza virus infection.

Kondo H, Otsuka K, Morimoto J, Arimochi H, Tsukumo SI, Yasutomo K
ImmunoHorizons 2025 Nov 9;9(11)

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Imidazole propionate ameliorates lipid metabolism in adipocytes to attenuate high-fat diet-induced obesity via PPAR signaling pathway.

Lin C, Peng Z, Du J, Shan X, Zhang Z, Xu L, Huang S, Gao J, Guo X
Lipids in health and disease 2025 Nov 7;24(1):356

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The impact of STAiR18 on multiple myeloma survival rates.

Wu Y, Wang H, Luo J, Lin J, Wu Y, Zheng S, Gao Y, Chen J, Che F, Shi J, Zhong L
Journal of translational medicine 2025 Nov 7;23(1):1243

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SETD7-mediated H3K4me1 activates ALDH1A3 to drive ferroptosis resistance in esophageal squamous cell carcinoma.

Feng Y, Liu X, Wang Y, Zhang M, Ji Y, Zhang L, Tong Y, Zhou F, Liu H, Ming L, Wan J
Cell death & disease 2025 Nov 7;16(1):810

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Inhibition of Galectin-3 by ADSC-derived exosomes after cavernous nerve injury ameliorates erectile dysfunction by modulating oxidative stress and inflammatory profibrotic cascades.

Li R, Wang G, Feng C, Diao T, Liu S, Fu Q
Stem cell research & therapy 2025 Nov 7;16(1):627

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Evaluation of a novel bioceramic sealer NeoSEALER Flo on the activation and polarization of macrophage.

Wang Z, Sun X, Chen Z, Yu J, Chen Z, Chang Z, Zhu L, Wang L
Odontology 2025 Nov 7;

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Iron addicted colorectal cancers exploit Heme-Complex II axis to resist oxidative cell death.

Jain C, Essani M, Kumar R, Das NK, Singhal R, Rossiter NJ, Chen B, Huang W, Lee ZH, Solanki S, Zhang Y, Sajjakulnukit P, Zhang L, Dalal PJ, Hanna DA, McCollum S, Stoffel EM, Greenson JK, Maher LJ, Lyssiotis CA, Banerjee R, Shah YM
bioRxiv : the preprint server for biology 2025 Nov 6;

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AAV-based gene therapy ameliorates neurological deficits in a mouse model of childhood-onset neurodegeneration with cerebellar atrophy.

Wada H, Hama N, Hasegawa K, Takamuku C, Yoshida M, Omura M, Araki A, Kuwako KI
Molecular therapy : the journal of the American Society of Gene Therapy 2025 Nov 5;33(11):5829-5839

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FPR1-dependent Pro-inflammatory Ccl4(high) monocytes/macrophages drive and predict sepsis-induced acute lung injury.

Li Y, Shi J, Yu T, Piao M, Tan J, Miao Y, Gong L, Dong S, Li X, Liu H, Yu J, Zhang Y, Zhang Q
Respiratory research 2025 Nov 5;26(1):308

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A mitochondria-targeted nanomedicine for myocardial ischemia/reperfusion injury with synergistic antioxidant and anti-inflammatory properties.

Li C, Zhang Z, Luo C, Lan W, Liu C, Liu W, Xiang H, Yang J, Tang Y, Wang X
Journal of nanobiotechnology 2025 Nov 5;23(1):705

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Combined effects of restriction factors and transduction adjuvants on lentiviral vector gene transfer efficacy.

Dewannieux M, Fofana F, Hamon K, Mormin M, Galy A
Scientific reports 2025 Nov 4;15(1):38643

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The relationship between high serum UA levels and decidualization and angiogenesis in endometrium.

Li J, He M, Huang M, Xiang J, Zhang L, Liu Y, Ma Y, Zeng X, Sun X
Scientific reports 2025 Nov 4;15(1):38574

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Inhibition of NPC Intracellular Cholesterol Transporter 1 Dually Regulates Aldosterone Secretion Via the Steroidogenic Acute Regulatory-Related Lipid Transfer Domain-3-Voltage-Dependent Anion Channel 1 Axis and Inositol 1,4,5-Trisphosphate Receptor Type 3-Calcium Signaling.

Chen J, Chen M, Hu J, Wu Z, Li H, Li W, He F, Peng C, Xu Y, Huang W, Gao R, Li Q, Ma L, Yang S
Journal of the American Heart Association 2025 Nov 4;14(21):e045554T

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Circulating Cathepsin D Exacerbates Injury-Induced Brain Damage by Promoting Neutrophil Infiltration Into the Brain.

Liang Y, Zhao D, Wu PF, Liang YQ, Zhang XW, Xing J, Sun X, An MX, Shi JX, Gao QH, Tian L, Sun HZ, Xue B, Jiang LB, Chen YH, Zhao WD
Journal of the American Heart Association 2025 Nov 4;14(21):e043416

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The influence of TC0668 on glycometabolism modulation in Chlamydia muridarum-infected host cells.

Yu N, Chen X, Yang W, Zhou Y, Hu Y, Zhou Z
Microbiology spectrum 2025 Nov 4;13(11):e0305124

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USP2-mediated PPARγ stabilization promotes hepatocellular carcinoma progression and M2 macrophage polarization via oleic acid.

Cao J, Chen K, Hu K, Mi X, Pan Y, Xiao D, Liu S, Xiao L, Zhou L, Tao Y, Tang J
Journal for immunotherapy of cancer 2025 Nov 4;13(11)

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Nuclear receptor ESRRA promotes ERα-positive breast cancer through dual action on super enhancers and promoters to regulate gene transcriptional programs.

Zheng ZZ, Chen L, Hu GS, Peng BL, Huang QX, Wang A, Wang C, Liu W
Science bulletin 2025 Nov 30;70(22):3822-3839

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Elesclomol-Induced Copper Influx Attenuates Lung Adenocarcinoma Progression With Involvement of the ER Stress/PCK2 Axis.

Zhao J, Chen Y, Lu D, Zeng Y, Li J, Zhu J, Lei Z, Huang JA, Liu Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Nov 30;39(22):e71250

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D-Dopachrome Tautomerase-Driven Astrocytic CCL7 Aggravates Neuropathology by Recruitment of Microglia Following Spinal Cord Injury.

Song H, Fu T, Geng Y, He B, Zhou Y, Cao Z, Cai R, Ji H, Wang Y, Zhu Z, Wang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Nov 30;39(22):e71248

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Hydrogen rescues vascular endothelial cells in obstructive sleep apnea-hypopnea syndrome by modulating nitric oxide.

Chen Q, Jiang D, He J, Sun M
Journal of thoracic disease 2025 Nov 30;17(11):9598-9609

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Hepatocyte growth factor alleviates alcoholic cardiomyopathy through the Nrf2 pathway-a focus on iron metabolism.

Yu Y, Chen J, Cao K, Zhang J
Journal of thoracic disease 2025 Nov 30;17(11):10149-10162

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Uridine-cytidine kinase 2 as a novel potential prognostic and therapeutic biomarker in gastric cancer.

Sun W, Guo H, Cai M, Ma G, Zhang L, Yu Y, Zhan H
Translational cancer research 2025 Nov 30;14(11):8070-8085

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Itaconate-functionalized tetrahedral framework nucleic acids break the dry eye vicious cycle through dual antioxidant and anti-inflammatory actions.

Jiang K, Lin Z, Cheng M, Chen Y, Jiang Y, Xu C, Zhu L, Gong B, Zhang C, Hong J
Journal of nanobiotechnology 2025 Nov 3;23(1):699

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Anthraquinone Rhein Mitigates Heavy Ion Radiation-Induced Lung Injury by Maintaining Thioredoxin Reductase/Thioredoxin (TrxR/Trx) Redox Homeostasis.

Chen Y, Wang J, Zhou X, Xu C, Xu D, Wu Q, Zhang J, Fang J
Molecular pharmaceutics 2025 Nov 3;22(11):6714-6727

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Integrated analysis of single-cell and bulk RNA sequencing identifies GSTM4 as a tumor suppressor and prognostic biomarker in breast cancer.

Yu Z, Yun W, Zhang Q, Li X, Zhao C, Liu X
Discover oncology 2025 Nov 3;16(1):2004

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Helicobacter pylori Lipopolysaccharide Upregulates MDM2 via the TLR4/MAPK/AP-1 Pathway to Promote Gastric Cancer Progression.

Li Y, Xu L, Lu X, Fu B, Jiang Q, Xiong W, Tang W, Wu D
Digestive diseases and sciences 2025 Nov 29;

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Comprehensive Transcriptomic Analysis and Experimental Validation of Notochordal Cells and Nucleus Pulposus Cells: Uncovering Novel Therapeutic Targets for Intervertebral Disc Degeneration.

Li Y, Cheng P, Zhang H, Chen S, Liu H, Wang K, Wang J, Kang X
Current issues in molecular biology 2025 Nov 28;47(12)

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Sestrin2 ameliorates LPS-induced cardiomyocyte injury by inhibiting ferroptosis via the Nrf2/HO-1 pathway.

Yang Y, Yang P, Zheng Z, Tian Q
European journal of medical research 2025 Nov 28;31(1):3

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CD209a regulates metabolic dysfunction-associated steatotic liver disease development through macrophage STAT3 signaling pathway.

Chen Y, Zhou J, Tang C, Zhu P, Xu Z, Song X, Zhang J, Cen L, Zeng H, Ke Y, Li Y, Chen Y, Wang J
Cellular & molecular biology letters 2025 Nov 28;30(1):141

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Rg1-preconditioned adipose-derived mesenchymal stromal cells alleviate colitis via exosome-mediated Inhibition of macrophage glycolysis through RAS signaling.

Fang Y, Chen Y, Yu X, Zhang J, Zhu W, Mou C, Wang D, Chen A, Zhang R, Liu Q, Li T, Jiang B
Stem cell research & therapy 2025 Nov 28;17(1):68

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RNF186 controls glucose metabolism in metabolic dysfunction-associated fatty liver disease.

Du J, Du Q, Zhang Y, Gao J, Wang C, Kou B, Jiang Y, Zhao D, Lin J
Cell & bioscience 2025 Nov 28;15(1):164

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Brain-derived extracellular vesicles circUsp32 polarized macrophages causing acute kidney injury after traumatic brain injury.

Fu J, Wu J, Du M, Wang X, Shi Q, Fang Y, Lan Y, Wu Q, Zhang G, Xu L, Yan H
Science advances 2025 Nov 28;11(48):eadz1243

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PPA1 promotes oxidative phosphorylation and malignant progression of colorectal cancer under glucose restriction via AMPK/ULK1/FUNDC1-mediated mitophagy.

Chen Y, Deng Q, Chen Z, Yang L, Li X, Fu Z
Cell death discovery 2025 Nov 28;11(1):549

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Bifidobacterium animalis subsp. lactis GOLDGUT-BB69 Counteracts Diarrhea in Mice by Alleviating Inflammation, Enhancing Intestinal Barrier Functions, and Regulating Intestinal Microbiota.

Zhao M, Li C, Fang Z, Yi Q, Ke X, Luo X, Zhou L, Wang Q
Probiotics and antimicrobial proteins 2025 Nov 28;

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H(2)S-Activated Theranostic Platform for Precise Photoablation of Colorectal Tumors with NIR-II Dual-Modal Phototherapy.

Wu K, Sun L, Wu H, Zheng X, Xue Y, Zhang Z, Ma S, Zhao C, Liu Y, Gu X
Journal of medicinal chemistry 2025 Nov 27;68(22):24684-24700

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Structure-Based Design and Optimization of Bi-Aryl Amide Derivatives as Nur77 Ligands for Nur77-Bcl-2-Dependent Apoptotic Cancer Therapy.

Zhao T, Chen J, Hong W, Zhong Y, Li H, Li X, Qiu Y, Wang L, Wu Z, Wang X, Chen X, Fang M
Journal of medicinal chemistry 2025 Nov 27;68(22):24168-24195

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Acetylbinankadsurin A Decreases Macrophage Glycolysis and Pro-Inflammatory Phenotype Polarization via Inhibiting HIF-1α to Alleviate Hepatic Fibrosis in Mice.

Yao Q, Peng W, Lu H, Yang Y, Rao Z, Xie X, Huang D, Wang W, Yan J, Liu J
Molecules (Basel, Switzerland) 2025 Nov 27;30(23)

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The role of CSTF2 in gastric cancer: implications for therapy.

Feng L, Cao Z, Shi X, Liu W, Xu W, Yu C, Ning J, Chen C
European journal of medical research 2025 Nov 27;30(1):1304

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NAMPT modulates muscle fiber type transition in PAD myopathy via the cGMP-PKG signaling pathway.

Yang Q, Shi Y, Li W, Xiong X, Chen Q, Zheng M
Biology direct 2025 Nov 27;20(1):113

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Ferroptosis mediated by ferritinophagy is involved in liver injury caused by sepsis.

Zhang H, Li H, Liu S, Zheng J, Li P
Scientific reports 2025 Nov 27;15(1):45489

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Exercise attenuates hepatic ectopic lipid deposition in high fat-diet rats via PKA-mediated phosphorylation of Perilipin5.

Dong S, Yang Y, Li W, Wang L, Li T
Scientific reports 2025 Nov 27;15(1):42466

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Short-Chain Fatty Acids Enhance EAAT2-Mediated Glutamate Clearance and Alleviate Oxidative Stress in an MPTP Mouse Model of Parkinson's Disease.

Li W, Li J, Liu L, Hu W, Wu L, Ding S, Yu B, Jiang L, Liu H
Antioxidants (Basel, Switzerland) 2025 Nov 27;14(12)

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Er Miao San Attenuates Collagen-Induced Arthritis Mice by Regulating Gut Microbiota and Its Metabolites.

Xu S, Su W, Qin Z, Xuan Z, Wang J, Wang J, Tang R, Yin J, Liang J, Jia X
Journal of microbiology and biotechnology 2025 Nov 26;35:e2507054

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Extracellular matrix anchored neutrophils drive pulmonary fibrosis in mice.

Yang L, Sun P, Wang J, Xu M, Zhu B, Yu K, Rong Y, Mao R, Zi S, Liu C, Huang J, Ma J, Chen H, Luo W, Zhang W, Zhang X, Fang S, Chao J
Nature communications 2025 Nov 26;16(1):11655

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Pharmacologic inhibition of PCBP2 biomolecular condensates relieves Alzheimer's disease.

Wang L, Xie XY, Pan QL, Zhang J, Zhou GF, Zhang QL, Yan XX, Xiang Y, Li CL, He Y, Xiang XJ, Deng XJ, Wang YJ, Zhou JY, Nie S, Chen GJ
Nature communications 2025 Nov 26;16(1):10514

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Methylene blue reduces postoperative delirium in mice through neuroinflammation suppression and blood-brain barrier repair.

Deng Y, Hua J, Pan H, Zhang J
Scientific reports 2025 Nov 26;15(1):42201

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Evolutionary dampening of Wnt signaling may contribute to naturally ascrotal testes in mammals.

Chai S, Zhong C, Zhang Z, Yin D, Xu S, Ren W, Yang G
Molecular biology and evolution 2025 Nov 26;

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p53-mediated regulation of electron transport chain and nucleotide synthesis during Newcastle disease virus infection.

Zhao C, Tang N, Wang J, Qu Y, Tan L, Song C, Qiu X, Liao Y, Luo T, Ding C, Sun Y
Journal of virology 2025 Nov 25;99(11):e0157625

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The neddylation of the RNA-dependent RNA polymerase 3D of Coxsackievirus B3 promotes viral replication.

Li S, Dong Y, Wang X, Feng D, Luan T, Wang Z, Lin L, Chen Y, Wang Y, Fei Y, Wang Y, Zhong Z, Zhao W
Journal of virology 2025 Nov 25;99(11):e0153525

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Stra8 links neuronal activity to inhibitory circuit protection in the adult mouse brain.

Huang M, Yue S, Zhang X, Wu L, Vivian JL, Wang ZJ, Wang N
Cell reports 2025 Nov 25;44(11):116513

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Scutellarin triggers ferroptosis in ovarian cancer cells via inhibiting AKT/mTOR and JAK2/STAT3 pathways.

Wang S, Zhang M, Tang C, Xia T, Gao L, Chen Q, Gao F, Ye W, Wang H, Jin M, Jiang X, Gao L, Xu Z, Zhu R, Yan X, Zhu J, Ye Z, Yan J, Zhang G, Wang W
Medical oncology (Northwood, London, England) 2025 Nov 25;43(1):24

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Targeted suppression of CCR7/NF-κB signaling by apoptotic body-inspired colchicine nanovesicles halts atherosclerotic progression.

Chen Q, Peng YS, Zhong Q, Zhang YB, Hu LB, Zhang GY, Xu YX, Dong PN, Shen S, Wang JH, Wang ZG, Zhang HT, Zeng R, Wang H
Journal of nanobiotechnology 2025 Nov 25;23(1):798

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Lipid metabolism-related genes correlate with immune microenvironment and regulate the efficacy of immunotherapy via ferroptosis in melanoma.

Zhang H, Chen Y, Guo S, Guo W
Discover oncology 2025 Nov 25;16(1):2297

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Deciphering the hepatoprotective mechanism of Sarcopyramis nepalensis wall against non-alcoholic fatty liver disease by network pharmacology and experimental validation.

Lai H, Zhu C, Li X, He L, Deng C, Guo L, Wang X
Scientific reports 2025 Nov 25;15(1):45324

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Huang-Lian-Jie-Du decoction alleviates diabetic ischemic stroke by modulating gut microbiota-derived short-chain fatty acids.

Chen C, Luo WH, Li A, Wu HZ, Chen DY, Chen JX, Wang ZQ, Wang SM, Tang D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157476

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Unveiling plumbagin as a novel metabolic modulator to suppress ACC1-mediated de novo lipogenesis in non-small cell lung cancer.

Deng ZH, He LJ, Wei S, Li CS, Chen Y, Ai XY, Chaotham C, Jiranusornkul S, Zhang PC, Luo Z, Xing SP, Yang J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157438

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Qihuang Yishen formula attenuates renal tubular injury by modulating inflammation via the cGAS/STING pathway in diabetic kidney disease.

Guo Y, Xue T, Meng X, Yan P, Zhang M, Zhang Q, Li T, Shi K, Zhang N
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157399

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Shen-Bai-Jie-Du decoction inhibits colorectal tumorigenesis by attenuating the malignancy of cancer stem cells via the gut microbiota-bile acid-FXR axis.

Zhang Y, Shen M, Baokan J, Xu L, Ni M, Jin J, Shen W, Sun D, Li L, Lai Y, Yan Q, Yu C, Tan J, Xu C, Tao L, Fan M, Cheng H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157366

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Shenqi compound ameliorates renal fibrosis in diabetic kidney disease by inhibiting LRG1/TGF-β/Smad signaling pathway.

Yuan Y, Liu L, Chen N, Tang S, Qi Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157355

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Ginsenoside compound K ameliorates depressive-like behaviors by targeting kynurenine 3-monooxygenase.

Li W, Kong Z, Yang L, Chen F, Chen Y, Han J, Sheng C, Zeng L, Hu Y, Zhao Y, Wang H, Bian Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157335

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An integrated study on the role and underlying mechanism of QingFei Oral solution in pulmonary hypertension.

Zou X, Cai A, Cheng Y, Li X, Chen Y, Li W, Zhang Y, Pan Z, Liu Y, Zhang Y, Liu T, Huang P
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157311

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The chemosensitizing activity of betulinic acid in suppressing macrophage polarization through GSK-3β/β-catenin/CXCL1 signaling in breast cancer.

Xu Z, Si J, Liang A, Zhang Y, Gong J, Li G, Zhong Y, Yu M, Feng R, Li X, Chang J, Wang N
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157304

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Integrating metagenomics, lipidomics and proteomics to explore the effect and mechanism of ginsenoside Rb1 on atherosclerosis co-depression disease.

Zhao Y, Song T, Ren P, Wu X, Luo Q, Xie J, Lai H, Li X, Wen Y, Liao X, Zhou J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157301

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3-O-Acetyloleanolic acid alleviates autoimmune liver injury by targeting FXR.

Wang Y, Li Z, Xiao W, Yongbo X, Li Y, Li Z, Chen D, Feng Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157273

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Liquiritin in Chaihu-shugan-san alleviates Parkinson's Disease via PPARα-mediated inhibition of SCD1/FADS2-dependent Ferroptosis.

Cai Y, Huang G, Shan C, Zhang X, YuYan L, Fu Y, Ren M, Yan T, Xu M, Zhu L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157262

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Integrative proteomics and metabolomics reveal that Terrestris saponin D ameliorates pulmonary fibrosis by regulating unsaturated fatty acid biosynthesis.

Zhang SN, Guo JJ, Zhao LS, Bo YK, Yang D, Yang XM, Li SM, Wu GD, An M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157232

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Silencing Clusterin Could Attenuate the Cell Properties of HCV Core Protein-Expressing HCC Cell Line.

Han F, Cui C, Cui J, Zang S, Zhao Z, Ren W, Zhang Q, Liu L, Dong S, Fu N, Nan Y
Digestive diseases and sciences 2025 Nov 25;

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GSTK1 suppresses HCC aggravation via L-carnitine metabolism by PGAM5/DRP1 complex-mediated mitochondrial quality control.

Shi Y, Zhang J, Song B, Zhang H, He J, Ding K, Wang F, Yu W, Zhangyuan G, Jin K, Zhang W, Sun B
Journal of experimental & clinical cancer research : CR 2025 Nov 24;45(1):1

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Image-guided therapy of colorectal cancer using a zirconium coordinated nanosensitizer.

Yang S, Jiao X, Lou X, Du Y, Zhao K, Shan L, Hong H, Feng M
Journal of nanobiotechnology 2025 Nov 24;23(1):732

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Dynamic remodelling of epithelial plasticity in colorectal cancer from single-cell and spatially resolved perspectives.

Xu C, Pan Y, Zhang S, Lin M, Liu H, Yu Z
Journal of translational medicine 2025 Nov 24;23(1):1341

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hnRNP A1 inhibits colorectal cancer tumorigenesis and progression by regulating fatty acid metabolism and RNA stability.

Ji K, Zhou L, Zhang T, Fan H, Xie G, Man W, Wang C, Tian Y, Chen L, Wang G, Liu M, Zhu B, Zhang W, Yu G
Cell death discovery 2025 Nov 24;11(1):542

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LETM2 regulates mitochondrial function and autophagy in diabetic foot ulcers: implications for oxidative stress and therapeutic targeting.

Su N, Wang J, Xue Z, Peng S, Xing W, Jin H, Zhao J, He Y, Shi J, Li W, Wei Q, Huang B, Li C, Wang X, Liu P, Yang N
Functional & integrative genomics 2025 Nov 22;25(1):251

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The CLIC1-PKM2 axis orchestrates glycolytic metabolism to accelerate gastric cancer progression.

Yang J, Yu Z, Feng Y, Wang S, Li C, Mao Y, Xu W, Chen J
Journal of translational medicine 2025 Nov 22;24(1):1

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Activation of the aryl hydrocarbon receptor relieves acute pancreatitis via the RBX1/HSF1 pathway.

Fang Y, Zhang C, Yu J, Shen X
Journal of inflammation (London, England) 2025 Nov 22;22(1):54

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Generation of antifungals to combat drug resistance using language models and diffusion models.

Wang Y, Dong Y, Zheng Y, Xu L, Song M, Chen J, Zhang K, Shen T, Zhao W, Lou H, Chang W
Journal of advanced research 2025 Nov 22;

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Methylprednisolone Restores Cognitive Impairment in mdx Mice by Inhibiting NF-κB/CCL5-mediated Neuroinflammation.

Zhang X, Han Z, Wang L, Luo H, Chen H, Cheng L, Jiang L
Molecular neurobiology 2025 Nov 21;63(1):122

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SENP3 mediated DeSUMOylation of macrophage derived CCL17 accelerates atherosclerosis via regulation of Treg.

Zhao X, Zhang F, Du J, Ding Y, Zhang Y, Zeng Y, Ye Y
Cell biology and toxicology 2025 Nov 21;41(1):151

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Niclosamide suppresses gastric cancer progression through YTHDF2 inhibition-affected lactate metabolic reprogramming.

Tang M, Hu Y, Zhu X, Dai J, Li R, Feng X, Chi K, Li X, Zhang Q, Chen K, Cao R, Zhu H, Huang H, Wu H, Sun L, Chen T, Wu J, Wang H, Gui Z
iScience 2025 Nov 21;28(11):113868

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Elucidating a novel prognostic signature for bladder cancer by integrating hypoxia and lactate metabolism-related genes: comprehensive bioinformatics analyses and experimental evidence.

Zhao Y, Li P, Shen Z, Yao S, Zhang X, Zhang N, Chen J
BMC cancer 2025 Nov 21;25(1):1796

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RBM15 mediates m6A methylation modification of FOSB mRNA to promote dysfunction of trophoblast cells-a potential link to preeclampsia.

Li Y, Li F, Gao Q
Hereditas 2025 Nov 21;162(1):241

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HAT1 functions as a lactyltransferase and mediates RPA1 lactylation to promote DNA repair and radioresistance in lung adenocarcinoma.

He J, Lai T, Zhao Y, Zhou Z, Zhou L, Tao D, Yang H, Li N, He Y, Yang S, Tang Z, Zeng S, Munai E, Liu Y, Tan Y, Zhou W, Wu Y
Cell death & disease 2025 Nov 21;16(1):851

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Hydrogen sulfide protects against hippocampal neuronal apoptosis in aged rats with postoperative cognitive dysfunction by promoting m6A methylation.

Wang B, Wen Y, Tang Y, Li M
Neuroscience letters 2025 Nov 20;868:138405

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TIM-3 Promotes Proliferation of Acute Myeloid Leukemia Blasts.

Shi ZY, Sun K, Li ZY, Xie DH, Qin YZ
Biomedicines 2025 Nov 20;13(11)

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Nanobodies Targeting the GP4 Protein Inhibit PRRSV Replication.

Zhang W, Wu A, Li H, He T, Dong Q, Zhang H, Chen J, Jiang S, Sheng J
Microorganisms 2025 Nov 2;13(11)

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Prolyl endopeptidase is a multifunctional host factor required for FMDV infection.

Ma K, Hao R, Liu T, Ru Y, Feng T, Qi X, Wang Y, Lu B, Wu S, Li D, Zhang R, Zhao Y, Zheng H
Cellular and molecular life sciences : CMLS 2025 Nov 19;82(1):408

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Neutralizing XCL1 Attenuates Brain Injury and Reduces Lymphocyte and Dendritic Cell Recruitment Following Intracerebral Hemorrhage in Mice.

Shi J, Chen S, Wang J, Rastegar-Kashkooli Y, Fu P, Huang M, Zhang J, Wang J, Jiang C
Molecular neurobiology 2025 Nov 19;63(1):70

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Targeting cancer stem-like cells via cholesterol modulation and ferroptosis induction using a multifunctional nanoplatform to overcome drug resistance.

Ye L, Zhu J, Wang X, Chen N, Sun Y, Zeng X, Liu S, Yan S
Journal of nanobiotechnology 2025 Nov 19;23(1):722

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Hexokinase 2-mediated histone H3K18la promotes PAI-1-dependent thrombosis in acute myeloid leukemia via tumor-endothelial crosstalk.

Bai Q, Qiu YX, Zeng H, Yao LH, Zhong FM, Xu YM, Zhang J, Huang B, Liu J, Shi H, Hou X, Wang ZH, Deng KY, Wang XZ
Nature communications 2025 Nov 19;16(1):10168

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FTO Suppresses Dental Pulp Stem Cell Senescence by Destabilizing NOLC1 mRNA.

Li B, Xu M, Huang J, Jia R
Biomolecules 2025 Nov 19;15(11)

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The cyclic peptide mallotumide A inhibits colon and breast cancer cell growth and motility by targeting cellular respiration and lipogenesis.

Laowittawat C, Sawektreeratana N, Katewongsa K, Payomhom P, Hongthong S, Reutrakul V, Kuhakarn C, Jitrapakdee S
Scientific reports 2025 Nov 19;15(1):40774

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Integrated analysis of Corylin from Psoralea Corylifolia inhibiting osteoporosis via MAPK pathway.

Liu N, Yang Z, Yanzhang R, Shen R, Yi W, Teng J
Scientific reports 2025 Nov 19;15(1):40724

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Hyperosmolarity-Induced Oxidative Stress Leads to Senescence in Human Corneal Epithelial Cells (HCEPC) via DNA Damage, Metabolic Disturbance and Mitophagy Decline.

Zhang Y, Fan T
Antioxidants (Basel, Switzerland) 2025 Nov 19;14(11)

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Rescuing fertility: C-Phycocyanin prevents ovarian damage through NRF2-mediated ferroptosis pathways in polycystic ovary syndrome models.

Zhang J, Shen QS, Chen YX, Cheng HR, Zhang W, Xing T, Liu YJ, Cao YX, Liang D, Luo M, Yu B
Zoological research 2025 Nov 18;46(6):1531-1548

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Integrative Transcriptomic and Metabolomic Analysis Reveals That Acanthopanax senticosus Fruit Ameliorates Cisplatin-Induced Acute Kidney Injury by Suppressing the NF-κB/PI3K-AKT Pathway via UGT1A1 Regulation.

Han L, Tang Z, Ma X, Zhang Q, Han Y, Wang Q, Liu J, Bian X, Gao L, Xu M, Sun X
International journal of molecular sciences 2025 Nov 18;26(22)

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Melittin inhibits NSCLC metastasis by targeting USP10 and promoting RNF20-mediated ubiquitination and degradation of PSMA7.

Wang Y, Li X, Zou Z, Yang W, Qian M, Zhou C, Xu J, Lu C, Xue F, Huang G, Jin M
Journal of translational medicine 2025 Nov 18;23(1):1312

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Mechanism of platelet-rich plasma in improving cyclophosphamide-induced premature ovarian failure in rats.

Zhao T, Xiao X, Li L, Wei Y, Shi H, Yang G, Yuan T
Stem cell research & therapy 2025 Nov 18;16(1):649

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DNA replication fork speed acts as a pacer in cortical neurogenesis.

Wang J, Kong Y, Li X, Chen D, Xiang K, Tan Y, Shi L
Nature communications 2025 Nov 18;16(1):10121

---

Novel bakuchiol derivatives inhibit the migration and invasion of non-small cell lung cancer by suppressing epithelial-to-mesenchymal transition.

Xu MF, Zhong K, Zhu J, Chen J, Liu F, Ding F, Wu CZ, Zhao L
RSC advances 2025 Nov 18;15(53):45233-45244

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Family with sequence similarity 114 member A1 orchestrates immune evasion in triple-negative breast cancer.

Zhang W, Gai Y, Qiao M, Rowicki M, Wei Y, Hang X, Wei Z, Yang H, Ye X, Ju H, Lu Y, Kang Y, Shen M
Signal transduction and targeted therapy 2025 Nov 18;10(1):373

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Dietary choline-derived Trimethylamine N-oxide impairs hippocampal neuronal function via PANoptosis activation.

Wang Y, Shen S, Sun Y, Zhou S, Zhang X, Song Z, Sun M, Jiang S, Qian C, Zhang Q, Zhang S, Wang M, Zhu B
NPJ science of food 2025 Nov 17;9(1):235

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Fusobacterium nucleatum-derived extracellular vesicles carrying virulence factor DNA trigger AIM2 inflammasome activation to facilitate UC progression.

Zhao Y, Wu R, Duan Y, Kong X, Zhang Y, You Y, Zhang J, Wang Y, Zhou L, Duan L
Cellular & molecular biology letters 2025 Nov 17;30(1):138

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Estrogen Attenuates Hypoxia-Induced TRPV1 Activation and Calcium Overload via HIF-1α Suppression in MCF-7 and CHO Cells.

Çiğ B
International journal of molecular sciences 2025 Nov 17;26(22)

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Epigenetic silencing of MSTN via m6A modification underlies the renoprotective effects of engineered MSC exosomes with RBM15 depletion in diabetic nephropathy.

Dong Q, Dong L, Zhu Y, Wang X, Yan X
Functional & integrative genomics 2025 Nov 17;25(1):244

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HOXA9 drives lymphatic metastasis by activating the c-MYC-glycolysis-lactate axis in gastric cancer.

Lu T, Shen G, Huang T, Mao X, He J, Hu Y
Journal of translational medicine 2025 Nov 17;23(1):1294

---

Distinct functional heterogeneity of TP53 R175 mutations in platinum-resistant ovarian cancer: unveiling molecular mechanisms and therapeutic targets.

Liu Y, Zheng Z, Ni M, Mao S, Xiao Y, Zhao Y, Tian B, Wang L, Xu H, Hua Y
Cell death & disease 2025 Nov 17;16(1):837

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Alpinetin pretreatment prevents lipopolysaccharide/D-galactosamine-induced acute liver injury in mice by inhibiting ferroptosis via the Nrf2/SLC7A11/GPX4 pathway.

Liu Y, Zhao J, Cong W, Liu T, Sha K
Scientific reports 2025 Nov 17;15(1):40065

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Knockdown of SUCLG2 inhibits glioblastoma proliferation and promotes apoptosis through LMNA acetylation and the mediation of H4K16la lactylation.

Li W, Zhang Q, Yin H, Li Q, Liu S, Wang J, Yuan G, Pan Y
Cell death discovery 2025 Nov 17;11(1):534

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MOF-Engineered Platelet-Mimicking Nanocarrier-Encapsulated Cascade Enzymes for ROS Scavenging and Anti-Inflammation in Cerebral Ischemia-Reperfusion Injury.

Li H, Xie X, Zhang Y, Han X, Shi T, Li J, Chen W, Wei Q, Pan H, Xu S, Chen Q, Yin L, Qin C
Pharmaceutics 2025 Nov 16;17(11)

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Ozone aging amplifies the tumor-promoting effects associated with low-dose graphene oxide exposure in bladder tumors via the integrin αV signaling pathway.

Zhu J, Yi B, Ma J, Zhang S, Zhou Z, Qi Y, Qi S
Ecotoxicology and environmental safety 2025 Nov 15;307:119458

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Prenatal BPA exposure disrupts androgen synthesis in testicular Leydig cells via epigenetic modifications of steroidogenic factor 1.

Hong Z, Xu Y, Xu Y, Ding M, Zhao Z, Wang C, Liu Z, Wu J
Ecotoxicology and environmental safety 2025 Nov 15;307:119409

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TIM3 attenuates morphine antinociceptive tolerance and microglial neuroinflammation by suppressing the TRAF6/NF-κB pathway in male mice.

Yang H, Shen T, Qi Z, Yang Z, Zhang M, Jiang J, Sun Z, Lu C
Neuropharmacology 2025 Nov 15;279:110638

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UFP-101 alleviates diabetic peripheral neuropathy through membrane metallo-endopeptidase.

Han Y, Qin YJ, Li J, Zhang CY, Wang TQ
European journal of pharmacology 2025 Nov 15;1007:178246

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An Optimized Platform Overcomes Excessive Tumor Immune Rejection Induced by the CRISPR/Cas9 Lentiviral System.

Shang Y, Li S, Xu T, Sun Y, Li F
Cancer research 2025 Nov 14;85(22):4315-4328

---

Nicotine Improves Memory Impairment in Aged Rats Through Enhanced Mitochondrial Homeostasis.

Ni Z, Li Y, Wang G, Wang S, Chen H, Hou H, Hu Q
Molecular neurobiology 2025 Nov 14;63(1):38

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AICAr Inhibition of cardiomyocyte autophagy promotes p62-dependent NRF2 expression and protection against doxorubicin toxicity.

Fassett EK, Mayer B, Fassett JT
Cellular and molecular life sciences : CMLS 2025 Nov 13;82(1):395

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Structure-Based Design of a Highly Potent Dual-Competitive FTO Inhibitor for Targeted m(6)A Demethylase Inhibition in AML.

Zhang X, Wang Z, Xie X, Liu G, Dong Z, Yang CG
Journal of medicinal chemistry 2025 Nov 13;68(21):22779-22798

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Precision Chemoradiotherapy via EGFR Targeting with Radiotherapy-Activated Drug Conjugates.

Lin S, Luo J, Yang J, Tan K, Xing Q, Zhang S, Gao Q, Geng J
Journal of medicinal chemistry 2025 Nov 13;68(21):22769-22778

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ML345 is a potent and selective NLRP3 inflammasome inhibitor with anti-inflammatory activity.

Lin H, Liang X, Hao W, Lu X, Li B, Wang X
Molecular biomedicine 2025 Nov 13;6(1):108

---

Human collagen III mRNA therapy for effective skin rejuvenation.

Zhang J, Chen S, Yang J, Song L, Chen L, Feng W, Ju R, Xie Z
Journal of translational medicine 2025 Nov 13;23(1):1283

---

Glutamine metabolism reprogramming promotes bladder cancer progression via PYCR1: a multi-omics and functional validation study.

Ding X, Zhang E, Huang Z, Li X, Wang Z, Wu Y, Liu C, Wu S
Journal of translational medicine 2025 Nov 13;23(1):1277

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Proteomic sensors for quantitative multiplexed and spatial monitoring of kinase signaling.

Comstock WJ, Navarro MVAS, Maybee DV, Rho Y, Wagner M, Jaber K, Wang Y, Smolka MB
Nature communications 2025 Nov 13;16(1):9902

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TGF-β2 increases eHSP90α secretion via upregulating secretory autophagy pathway.

Li J, Li J, Xie T, Huang S, Tian H, Liu M, Kong X, Zhang D, Nawaz KI, Wang M, Li H, Zhang J, Yuan F, Guo W, Cui X, Mu H, Hu Y
Cell communication and signaling : CCS 2025 Nov 12;23(1):492

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Comprehensive pan-cancer analysis of USP35 and validation of its role in gastric cancer.

Yan L, Zhang Y, Wang S, Qin J, Chen M, Zou D, Zhang L, Wu L, Zhang Y
Human genomics 2025 Nov 12;19(1):134

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An effector of phosphatidylinositol 3-kinase activity promotes Rickettsia rickettsii virulence by enhancing autophagy.

Huang D, OuYang X, Peng Z, Chen D, Song L, Luo Z-Q
mBio 2025 Nov 12;16(11):e0228425

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Genome-wide mapping of EBV-induced genomic variations identifies the role of MUC19 in EBV latency.

Yu J, Wang Y, Liu Q, Zhou X, Robertson ES, Pei Y
mBio 2025 Nov 12;16(11):e0205525

---

Xiaoyao San against depression via glia-mediated neuroinflammation using network pharmacology and experimental validation.

Liu XY, Yan YZ, Jiang AJ, He WY, Fang YY, Li CH, Deng MF, Tan SJ, Zeng P
Scientific reports 2025 Nov 12;15(1):39708

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Mechanism of the traditional Chinese medicine SMBJ alleviates diabetes mellitus-induced Leydig cell dysfunction in rats testes.

Zhang W, Liu Y, Tong L, Jin Y, Gao C, Cui Y, Jin B, Sun D
Scientific reports 2025 Nov 12;15(1):39656

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Partial TEX14 peptides inhibit proliferation of cancer cells and have potential as anti-tumour agents.

Iwamori T, Sakurai Y, Sultana T, Katakura Y, Iwamori N
Human cell 2025 Nov 11;39(1):6

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Dietary Glycerol Monolaurate Effect on Growth Performance, Intestinal Barrier Function, and Gut Microbiota in Weaned Piglets Challenged by Lipopolysaccharide.

Wang H, Ma R, Qi R, Liu Z, Li Y, Wu X, Zhao C, Ma Q, Zhan K
Animals : an open access journal from MDPI 2025 Nov 11;15(22)

---

Erianin is a therapeutic candidate for addressing neuroinflammation triggered by intracerebral hemorrhage.

Li SW, Wang HC, Chen MS
Langenbeck's archives of surgery 2025 Nov 10;411(1):10

---

A general nanoplatform for nucleotide drug delivery: From molecular binding to antiviral therapy.

Zhou Z, Zhang F, Li X, Zhang Y, Xie X, Liu Q, Xia P, Wang X, Ye M
Journal of controlled release : official journal of the Controlled Release Society 2025 Nov 10;387:114245

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Wuling San ameliorates cerebral ischemia-reperfusion injury via suppression of the TRPM2/NLRP3 pathway.

Li H, Tao D, Chen Y, Deng Y, Wei W, Xue X
European journal of medical research 2025 Nov 10;30(1):1096

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Ginsenoside Rh2 as a novel PIN1 inhibitor disrupting the cancer stem cell-like phenotype in non-small cell lung cancer.

Liu X, Mao Z, Yang J, Zhu Q, Dong X, Huang G, Shen X, Zhang L, Yang H
Journal of translational medicine 2025 Nov 10;23(1):1256

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Nrf2 alleviates excessive deposition of extracellular matrix in mammary fibrosis through TGF/Smad and ROS signals.

Kan X, Xu P, Yu M, Guo W, Cao Y, Hu G, Liu J, Fu S, Bi J
Scientific reports 2025 Nov 10;15(1):39252

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Targeting cuproptosis by FDX1 in acetaminophen-induced liver injury.

Liu Y, Yang Y, Peng B, Ou Z, Zuo A, Jiang Z, Wu C, Kwan HY, Ma K, Yu L, Zhao X
Chemico-biological interactions 2025 Nov 1;421:111753

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Biliverdin alleviates cerebral ischemia-reperfusion injury by inhibiting autophagy via the lncRNA TUG1 /miR-204-5p/P4HB axis.

Zhou G, Bai W, Jiang H, Li J, Huangfu J, Li X, Shu S, Liu J, Shao J
Life sciences 2025 Nov 1;380:123967

---

Cisplatin transported by COX17 induces cochlear damage by binding Myosin IIA to regulate cell pyroptosis induced by mitochondrial dysfunction.

Peng J, Tao G, Chen X, Ai Y, Lai R, Liu W, Hu B, Xu Y, Xie B, Li L
Life sciences 2025 Nov 1;380:123961

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Integrated multi-omics profiling identifies Cmpk1 as a monocyte-specific therapeutic target for renal ischemia-reperfusion injury.

Zhang H, Zhang G, Wang B, Xiong F, Ji X, Wang C
Life sciences 2025 Nov 1;380:123924

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Underlying metabolic syndrome exacerbates Vibrio vulnificus-induced acute kidney injury via systemic Th17/Treg dysregulation.

More MP, Saha P, Roy S, Trivedi A, Chatterjee S
American journal of physiology. Renal physiology 2025 Nov 1;329(5):F627-F644

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RACK1 is required for normal B cell development and signaling but not RAG1 degradation.

Palmer VL, Schabla NM, Kumar V, Swanson PC
Journal of immunology (Baltimore, Md. : 1950) 2025 Nov 1;214(11):3003-3016

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The compound (E)-2-(3,4-dihydroxystyryl)-3-hydroxy-4H-pyran-4-one alleviates neuroinflammation and cognitive impairment in a mouse model of Alzheimer's disease.

Liu X, Wu W, Li X, Wang C, Chai K, Yuan F, Zheng H, Yao Y, Li C, Ye ZC, Zha D
Neural regeneration research 2025 Nov 1;20(11):3330-3344

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Shengmai Jianghuang San enhances radiosensitivity of hypoxic nasopharyngeal carcinoma by inhibiting cancer stemness.

Su C, Gong F, You Y, Jiang Z, Wen X, Wang Y, Lin S, Li F, Li J, Liu Y, Zhu D, Fan Q
QJM : monthly journal of the Association of Physicians 2025 Nov 1;118(11):817-829

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Oxidative damage to lung mitochondrial DNA is a key contributor to the development of chemical lung injury.

Dubey S, Yu Z, Stephens EM, Lazrak A, Ahmad I, Aggarwal S, Andrabi S, Hossain MI, Jilling T, Fernandez SR, Bartels JL, Lapi SE, Mobley JA, Pastukh VM, Gillespie MN, Matalon S
Redox biology 2025 May;82:103624

---

Glucagon-like peptide-1 receptor signaling activation in alveolar type II cells enhances lung development in neonatal rats exposed to hyperoxia.

Sun T, Yu H, Zhang D, Zhang D, Li D, Fu J
Redox biology 2025 May;82:103586

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Molecular biomarkers for the prognosis of breast cancer: role of amino acid metabolism genes.

Zhou Y, Yu S, Zhu L, Wang Y, Duan C, Li D, Du J, Zhang J, Zhang J, Ma R, He J, Ren Y, Wang B
Journal of physiology and biochemistry 2025 May;81(2):441-457

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Activation of TRPA1 prevents metabolic dysfunction-associated steatotic liver disease in diet-induced obese mice through stimulating the AMPK/CPT1A signaling pathway.

Wang D, Liu S, Wan J, Chen S, Feng K, Hou J, Yang Y, Wang P
Journal of physiology and biochemistry 2025 May;81(2):359-373

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The TWIK2-mtDNA-NLRP3 inflammasome signaling in hepatic macrophages facilitates exercise-induced attenuation of hepatic inflammation and insulin resistance in db/db mice.

Zhang T, Fan J, Wen X, Duan X
Journal of physiology and biochemistry 2025 May;81(2):313-328

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FSP1 Acts in Parallel with GPX4 to Inhibit Ferroptosis in Chronic Obstructive Pulmonary Disease.

Yang Y, Shen W, Zhang Z, Dai Y, Zhang Z, Liu T, Yu J, Huang S, Ding Y, You R, Wang Z, Wu Y, Bian T
American journal of respiratory cell and molecular biology 2025 May;72(5):551-562

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NFAT2 Induces Tumor Cell Proliferation and Metastasis by Acting as a Transcriptional Co-activator of the TGF-β1/SMAD Signaling Pathway and Inducing the Epithelial-Mesenchymal Transition in Liver Cancer.

Liu Y, Mo W, Sun W, Chen J, Chen J, Li Y, Han D, Dai W, Zhang R
Digestive diseases and sciences 2025 May;70(5):1799-1812

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Protective Effects of Rat Bone Marrow Mesenchymal Stem Cells-Derived Fusogenic Plasma Membrane Vesicles Containing VSVG Protein Mediated Mitochondrial Transfer on Myocardial Injury In Vitro.

Liu X, Bian H, Zhou T, Zhao C
FASEB bioAdvances 2025 May;7(5):e70010

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Isowalsuranolide targets TrxR1/2 and triggers lysosomal biogenesis and autophagy via the p53-TFEB/TFE3 axis.

Yang X, Ding X, Zhao Y, Wang Y, Dong X, Niu Z, Gu Z, Fei J, Zhao Y, Hao X
Science China. Life sciences 2025 May;68(5):1437-1451

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METTL3 Promotes OSCC Progression by Down-Regulating WEE1 in a m6A-YTHDF2-Dependent Manner.

Su Y, Hu Y, Qu B, Lei R, Guo G
Molecular biotechnology 2025 May;67(5):1867-1879

---

Th22 cells promote the transition from homeostatic to reactive microglia in diabetic encephalopathy.

Yu SX, Yu HD, Wang YF, Yao TF, Lv SZ, Wang YC, Li JQ, Liu WQ, Ding JY, Liu XZ, Zuo ZF, Liu WP
Acta diabetologica 2025 May;62(5):633-650

---

Methamphetamine and HIV-1 Tat Protein Synergistically Induce Endoplasmic Reticulum Stress to Promote TRIM13-Mediated Neuronal Autophagy.

Wang C, Yang G, Huang J, Tian Y, Leung CK, Miao L, Wang H, Li Y, Huang Y, Teng H, Liu L, Li J, Zeng X
Molecular neurobiology 2025 May;62(5):6150-6165

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Inhibition of the Integrated Stress Response Prevents Natural Forgetting and Corrects Accelerated Forgetting Associated with Epilepsy.

Wang SY, Wang B, Li LY, Zuo Y, Jin X, Zhang B, Tian SW
Molecular neurobiology 2025 May;62(5):6059-6069

---

Tripartite Motif Containing 65 Deficiency Confers Protection Against Acute Kidney Injury via Alleviating Voltage-Dependent Anion Channel 1-Mediated Mitochondrial Dysfunction.

Chen T, Zhang Y, Ding L, Xiong C, Mei C, Wei S, Jiang M, Huang Y, Chen J, Xie T, Zhu Q, Zhang Q, Huang X, Chen S, Li Y
MedComm 2025 May;6(5):e70149

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SIRT1 Alleviates Oxidative Stress-Induced Mitochondrial Dysfunction and Mitochondria-Associated Membrane Dysregulation in Stress Urinary Incontinence.

Chen L, Tang J, Zuo X, Li B, Liu C, Hong S, Min J, Hu M, Li S, Zhou M, Chen M, He Y, Xiao Y, Huang X, Hong L
Cell proliferation 2025 May;58(5):e70009

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Platelet activation stimulates macrophages to enhance ulcerative colitis through PF4/CXCR3 signaling.

Niu Y, Li A, Xu W, Zhang R, Mei R, Zhang L, Zhou F, Pan Q, Yan Y
International journal of molecular medicine 2025 May;55(5)

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Yi Shen Tiao Gan decoction alleviates aromatase inhibitor-related bone loss by promoting H-type vessel formation.

Chu M, Zhang Y, Ye M, Yin Y, Chen H
Translational oncology 2025 May;55:102377

---

MiR-519d-3p from Placenta-Derived Exosomes Induce Immune Intolerance Regulating Immune Cells, Contributing to the Pathogenesis of Preeclampsia.

Cao SQ, Jiang TX, Guo YY, Lin R, Lin L
Immunological investigations 2025 May;54(4):522-543

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Cisplatin-induced acute kidney injury increased brain 5-hydroxytryptamine levels partly due to the hippuric acid-induced upregulation of CYP2D4 expression and function in the brain of rats.

Lu L, Hu N, Chen H, Wang S, Deng Y, Lin Z, Wang Z, Zhu X, Liu X, Liu L, Jiang L
Drug metabolism and disposition: the biological fate of chemicals 2025 May;53(5):100068

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Flavokawain a induces cell cycle arrest through CDT1-dependent p27 regulation and synergizes with venetoclax in acute myeloid leukemia.

Jin L, Jiang X, Li Y, Xiang S, Pei R, Lu Y, Jiang L
Toxicology and applied pharmacology 2025 May;498:117305

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Exploring the mechanism of baicalein on breast cancer based on network pharmacology, molecular docking and in vivo experiments.

Zhang G, Liu Z, Xu Y, Cao F, Huo X, Chen Q, Luo D
Toxicology and applied pharmacology 2025 May;498:117297

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2-Dodecyl-6-Methoxycyclohexa-2,5-Diene-1,4-Dione from Averrhoa carambola L. roots: Suppressing hepatocellular carcinoma progression through ROS accumulation and p53 pathway-mediated apoptosis.

Chen M, Pang H, Pham TTH, He Y, Gao Q, Liao Y, Zhu C, Chen L, Yan G, Mo S, Han C
Toxicology and applied pharmacology 2025 May;498:117296

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The antitumor effects and apoptotic mechanism of 20(S)-Protopanaxadiol in acute myeloid leukemia.

Zhang Y, Ma S, Xu Y, Wu S, Wu S, Liu M, Guo Y, Zhan Y
Journal of ginseng research 2025 May;49(3):306-314

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KMT2A facilitates the epithelial-to-mesenchymal transition and the progression of ovarian cancer.

Zhu Y, Jiang S, Tang R, Chen H, Jia G, Zhou X, Miao J
Molecular and cellular biochemistry 2025 May;480(5):3001-3017

---

Divalent metal ions enhance bone regeneration through modulation of nervous systems and metabolic pathways.

Luo Y, Liu B, Qiu Y, Li L, Yang F, Zhang C, Wang J
Bioactive materials 2025 May;47:432-447

---

Dental pulp stem cells alleviate Schwann cell pyroptosis via mitochondrial transfer to enhance facial nerve regeneration.

Zheng X, Wang J, Zhou H, Chai Y, Li Z, Chen M, Yang Z, Xu C, Lei C, He Y, Zou D, Ye Q
Bioactive materials 2025 May;47:313-326

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The Role of CXCL13 in GC-1 Cell Cycle Arrest Induced by Titanium Dioxide Nanoparticles Through JAK2/STAT3 Signaling Pathway.

Lei Y, Dong R, Sun C, Hu Y, Yan Y, Song G, Wang Y
Journal of applied toxicology : JAT 2025 May;45(5):830-840

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Simulated microgravity activates autophagy expression in the rat retina.

Liu M, Wang Y, Ren F, Zhang W, Zheng H, Zhang R, Gao C, Luo L, Nie C, Gu J
Life sciences in space research 2025 May;45:107-116

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S-palmitoylation modulates ATG2-dependent non-vesicular lipid transport during starvation-induced autophagy.

Zheng W, Pu M, Zeng S, Zhang H, Wang Q, Chen T, Zhou T, Chang C, Neculai D, Liu W
The EMBO journal 2025 May;44(9):2596-2619

---

PRSS23-eIF4E-c-Myc axis promotes gastric tumorigenesis and progression.

Zhou X, Guo Z, Pan Y, Yang S, Yan R
Oncogene 2025 May;44(17):1167-1181

---

Phospho-TRIM21 orchestrates RPA2 ubiquitination switch to promote homologous recombination and tumor radio/chemo-resistance.

Zhang J, Chen B, Xu F, Wang R, Zhao X, Yao Z, Zhang J, Zhou S, Xu A, Wu L, Zhao G
Oncogene 2025 May;44(16):1106-1117

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CREB1-BCL2 drives mitochondrial resilience in RAS GAP-dependent breast cancer chemoresistance.

Man KF, Darweesh O, Hong J, Thompson A, O'Connor C, Bonaldo C, Melkonyan MN, Sun M, Patel R, Ellisen LW, Robinson T, Song D, Koh SB
Oncogene 2025 May;44(16):1093-1105

---

Nuclear Factor Erythroid 2-Related Factor 2 Activator DDO-1039 Ameliorates Podocyte Injury in Diabetic Kidney Disease via Suppressing Oxidative Stress, Inflammation, and Ferroptosis.

Liu X, Zhai X, Wang X, Zhu X, Wang Z, Jiang Z, Bao H, Chen Z
Antioxidants & redox signaling 2025 May;42(13-15):787-806

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Metabolome-wide association identifies ferredoxin-1 (FDX1) as a determinant of cholesterol metabolism and cardiovascular risk in Asian populations.

Sadhu N, Dalan R, Jain PR, Lee CJM, Pakkiri LS, Tay KY, Mina TH, Low D, Min Y, Ackers-Johnson M, Thi TT, Kota VG, Shi Y, Liu Y, Yu H, Lai V, Yang Y, Tay D, Ng HK, Wang X, Wong KE, Lam M, Guan XL, Bertin N, Wong E, Best J, Sarangarajan R, Elliott P, Riboli E, Lee J, Lee ES, Ngeow J, Tan P, Cheung C, Drum CL, Foo RS, Michelotti GA, Yu H, Sheridan PA, Loh M, Chambers JC
Nature cardiovascular research 2025 May;4(5):567-583

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Saikosaponin D suppresses esophageal squamous cell carcinoma via the PI3K-AKT signaling pathway.

Duan Q, Wang M, Cui Z, Ma J
Naunyn-Schmiedeberg's archives of pharmacology 2025 May;398(5):6059-6070

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Identification of potential mechanisms of Schisandrin B in the treatment of idiopathic pulmonary fibrosis by integrating network pharmacology and experimental validation.

Pan T, Wu J, Qiu X, Zhu D, Wang J, Li T, Wang Z, Feng F, Xu Y, Zhou X
Naunyn-Schmiedeberg's archives of pharmacology 2025 May;398(5):5389-5403

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Reprogramming of Hypoxia-Induced Metabolic Disorder in Mouse Kidneys by Mesenchymal Stem Cells Through Improving Mitochondrial Dynamics and Function.

Wang Y, Ding Y, Wuren T, Luo P
Journal of biochemical and molecular toxicology 2025 May;39(5):e70291

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Forsythiaside A Alleviates Ulcerative Colitis and Inhibits Neutrophil Extracellular Traps Formation in the Mice.

Wang Z, Yan W, Lin X, Qin G, Li K, Jiang L, Li X, Xiao X, Luo T, Hou Y
Phytotherapy research : PTR 2025 May;39(5):2165-2179

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Angelica dahurica Polysaccharides Ameliorate Colitis by Reducing the Restriction of Gut Microbiota-Derived Imidazole Propionate on PPAR-γ Signaling Activation.

Hu J, Xu F, Zhu L, Cui Y, Au R, Li Y, Tong Y, Shen H
Phytotherapy research : PTR 2025 May;39(5):2072-2090

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Nose-to-Brain Delivery of Circular RNA SCMH1-Loaded Lipid Nanoparticles for Ischemic Stroke Therapy.

Jia Y, Xu L, Leng S, Sun Y, Huang X, Wang Y, Ren H, Li G, Bai Y, Zhang Z, Han B, Shen L, Ju M, Chen L, Yao H
Advanced materials (Deerfield Beach, Fla.) 2025 May;37(19):e2500598

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Activation of sigma 1 receptor attenuates doxorubicin-induced cardiotoxicity by alleviating oxidative stress, mitochondria dysfunction, ER stress-related apoptosis, and autophagy impairment.

Al-Maamari A, Sultan M, Wu S, Zhang T, Wang C, Han B, Duan Y, Ding SS, Chen N, Zhang H, Sun F, Chen X, Yu D, Su S
International journal of biological macromolecules 2025 May;310(Pt 4):143549

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Structural characterization and alleviative effects of novel polysaccharides from Artemisia sphaerocephala Krasch seed on obese mice by regulating gut microbiota.

Zeng X, Yu P, Li D, Li Y, Wang X, Yang X, Ren D
International journal of biological macromolecules 2025 May;310(Pt 4):143407

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Acetylation of Hsc70 at K512 inhibits goat ovarian granulosa cell senescence by restoring chaperone-mediated autophagy.

Li Y, Wang Y, Yao H, Li Z, Wang L, Song S, Li J, Li Y, Yang M, Zhang K, Han Y, Zhao Y, Yao S, Li Q, Ma Z, Xu D, Zhao Z
International journal of biological macromolecules 2025 May;310(Pt 2):143119

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Lysozyme (LYZ) promotes PEDV replication via degrading m(6)A methylation of RIG-I transcripts through YTHDF2.

Zhang Y, Zhang Q, Li S, Zhao Y, Lv X, Xu X
International journal of biological macromolecules 2025 May;310(Pt 1):143297

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Identification of preventive biomarkers associated with circadian rhythms in traumatic brain injury-mediated depression: Expression of SERPINE1 protein and bioinformatics analysis.

Cai Y, Huang G, Ren M, Zhang X, Yan T, Zhu L
International journal of biological macromolecules 2025 May;310(Pt 1):143229

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Calcitriol Modulates Hippocampal Axon Guidance Through Enhanced EfnA4-Mediated PI3K/AKT Signaling in an Autism Mouse Model.

Gong T, Sun R, Bai J, Liu X, He C, Jiang Q, Wang Q, Qi Y, Ding W, Shen J, Lei L, Shan Z
CNS neuroscience & therapeutics 2025 May;31(5):e70429

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11,12-Diacetyl-Carnosol Ameliorates Depression-Like Behaviors and Memory Dysfunction in CUMS Mouse Model via Inhibiting HMGB1-Mediated Neuroinflammation.

Zhao K, Xiang L, Yang S, Chen X, Yang X, Dong J, Wu S, Yang S, Zhang M, Hu W
CNS neuroscience & therapeutics 2025 May;31(5):e70406

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LncPrep + 96kb inhibits ovarian fibrosis by upregulating prolyl oligopeptidase expression.

Zhang H, Wang J, Liu J, Fan X, Jia Y, Huang Y, Han Q, Wang S, Xiao L, Li X, Zhang C
Molecular medicine reports 2025 May;31(5)

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Investigating the molecular mechanism of purslane‑based vitiligo treatment using network pharmacology, molecular docking and in vitro analyses.

Zhang X, Meng L, Ran X, Li S, Wen C
Molecular medicine reports 2025 May;31(5)

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Direct preparation of Cas9 ribonucleoproteins with an extended 'gRNA-shRNA' construct in Escherichia coli for precise genome manipulation.

Qiao J, Sun W, Yin W, Hu L, Wang X, Liu Y
International journal of biological macromolecules 2025 May;309(Pt 4):143121

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Serine protease Rv2569c inhibits inflammatory response and promotes intracellular survival of Mycobacterium tuberculosis by targeting the RhoG-NF-κB-NLRP3 pathway.

Zang X, Zhang J, Feng T, Wang H, Cui Y, Jiang Y, Chen C, Liu S, Dang G
International journal of biological macromolecules 2025 May;309(Pt 4):143022

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Bimetallic chitosan/hyaluronic acid nanoparticles self-amplify ferroptosis/cuproptosis in triple-negative breast cancer.

Wang J, Wang J, Zhang J, Ye H, Wang D, Tao L, Yao Y, Chen Y, Shen X
International journal of biological macromolecules 2025 May;308(Pt 4):142535

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Total dietary fiber of tartary buckwheat alleviates T2DM through the IRS-1/PI3K/AKT pathway and gut microbiota-bile acids-TGR5/FXR axis in db/db mice.

Liu X, Fang W, Pang S, Song G, Wang Y, Qi W
International journal of biological macromolecules 2025 May;308(Pt 3):142145

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FAM134B-mediated ER-phagy alleviates alcohol-related liver fibrosis by reducing endoplasmic reticulum stress.

Wang T, Li X, Xia G, Gong M, Lv X
International journal of biological macromolecules 2025 May;308(Pt 2):142395

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The glutamine starvation-induced lncRNA FERRIN suppresses ferroptosis via the stabilization of SLC7A11 mRNA.

Liu K, Wang Z, Guo X, Luo J, Wu X, Wang F, Mei Y
International journal of biological macromolecules 2025 May;308(Pt 1):142388

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Larimichthys crocea isinglass polysaccharide attenuates DSS-induced colitis via gut microbiota regulation and NF-κB signaling inhibition.

Sui D, Li M, Ai C, Li S, Chang H, Li Y, Zhao S, Li H, Ren X
International journal of biological macromolecules 2025 May;307(Pt 3):142263

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Activation of IL-2/IL-2R pathway by Hedyotis diffusa polysaccharide improves immunotherapy in colorectal cancer.

Bai L, Liu X, Yuan Z, Xu G, Li X, Wan Z, Zhu M, Liang X, Li P, Lan Q, Yu H, Tang G, Huang M, Peng S, Lin J, Wang X, Luo Y, Wei G
International journal of biological macromolecules 2025 May;306(Pt 4):141013

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Unveiling an indole derivative YM818 as a novel tyrosinase inhibitor with anti-melanogenic and anti-melanin transfer effects.

Yang C, Lai H, Yang X, Huang Y, Shi Y, Ke L, Chen L, Chen M, Chen H, Wang Q
International journal of biological macromolecules 2025 May;306(Pt 2):141557

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COL1A1 promotes cell proliferation, cell cycle progression, and anoikis resistance in granulosa cells of chicken pre-ovulatory follicles.

Li X, Luo X, Zhang X, Guo Y, Cheng L, Cheng M, Tang S, Gong Y
International journal of biological macromolecules 2025 May;306(Pt 2):141524

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A novel nuclear receptor NR1D1 suppresses HSD17B12 transcription to regulate granulosa cell apoptosis and autophagy via the AMPK pathway in sheep.

Cai Y, Xu H, Deng K, Yang H, Zhao B, Zhang C, Li S, Wei Z, Wang Z, Wang F, Zhang Y
International journal of biological macromolecules 2025 May;306(Pt 1):141271

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Fusobacterium necrophorum mediates the inflammatory response in the interdigital skin and fibroblasts of dairy cows via the TNF-α/TNFR1/NF-κB pathway.

Yue Y, Zhang A, Liu M, Ge Y, Xu E, Zheng J
Veterinary microbiology 2025 May;304:110483

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Foxp3 inhibits PCV2 replication by reducing the ATPase activity of Rep.

Jiang R, Huang Q, Shen R, Zhang Y, Zhou L, Ge X, Han J, Guo X, Yang H
Veterinary microbiology 2025 May;304:110441

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β-hydroxybutyrate serves as a regulator in ketone body metabolism through lysine β-hydroxybutyrylation.

Fang J, Hu Z, Luo T, Chen S, Li J, Yang H, Sheng X, Zhang X, Zhang Z, Xie C
The Journal of biological chemistry 2025 May;301(5):108475

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Ginsenoside Rg1 alleviates ochratoxin A-induced liver inflammation in ducklings: Involvement of intestinal microbiota modulation and the TLR4/NF-κB pathway inhibition.

Zhai S, Peng X, Liu C, Zhang R, Jin C, Jiang X, Feng P, Liang Y, Yuan X, Zhang J, Yang Y
Ecotoxicology and environmental safety 2025 May;296:118186

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Immune response to polystyrene microplastics: Regulation of inflammatory response via the ROS-driven NF-κB pathway in zebrafish (Danio rerio).

Pei J, Chen S, Ke Q, Pang A, Niu M, Li N, Li J, Wang Z, Wu H, Nie P
Aquatic toxicology (Amsterdam, Netherlands) 2025 May;282:107308

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Pyrimidine metabolism reshapes immune microenvironment and implies poor prognosis in glioma.

Huang R, Yang J, Li X, Chen H, Liu X
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2025 May;27(5):2127-2142

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Therapeutic role of Prunella vulgaris L. polysaccharides in non-alcoholic steatohepatitis and gut dysbiosis.

Zhu MJ, Song YJ, Rao PL, Gu WY, Xu Y, Xu HX
Journal of integrative medicine 2025 May;23(3):297-308

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Expression, characterization and anti-colon cancer activity of recombinant ginseng peptides with amino acid tandem repeats.

Feng Y, Li W, Yuwen W, Xu R, Zhu C, Duan Z, Fan D
Protein expression and purification 2025 May;229:106663

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AdipoRon attenuates depression-like behavior in T2DM mice via inhibiting inflammation and regulating autophagy.

Zhao W, Li Y, Zhou Y, Zhao J, Lu Y, Xu Z
Brain research bulletin 2025 May;224:111308

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Neuroprotective effects of hirudin against cerebral ischemia-reperfusion injury via inhibition of CCL2-mediated ferroptosis and inflammatory pathways.

Liao J, Chen H, Liao Y, Luo C, Wang Z, Zhang F, Fu C
Brain research bulletin 2025 May;224:111293

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Hypersine H, One Undescribed Xanthone From the Hypericum elodeoides Choisy With Anti-Neuroinflammation Activity.

He S, Liu X, Wang T, Li J, Lin Y, Zhou M, Sun C, Ding R, Wang G, Chen HF, Tian WJ
Chemistry & biodiversity 2025 May;22(5):e202403037

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Xixin Decoction May Treat Vascular Dementia by Modulating the NPTX2/C1q/C3 Complement Pathway.

Yang S, Gao XQ, Tan AH, Ge P
Chemistry & biodiversity 2025 May;22(5):e202402208

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CHPF2 as a novel biomarker and ponicidin as a potential therapeutic agent in hepatocellular carcinoma.

Liang Z, Ye Y, Deng Z, Lan H, Liu C, Xu Y, Fan M, Liu Z, Wu P, An L, Wang C
Pharmacological research 2025 May;215:107698

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ZACN Associated with Poor Prognosis Promotes Proliferation of Kidney Renal Clear Cell Carcinoma Cells by Inhibiting JTC801-Induced Alkaliptosis.

Li Y, Li C
Applied biochemistry and biotechnology 2025 May;197(5):3346-3362

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Identification of PIF1 as a Ferroptosis-Related Prognostic Biomarker Correlated with Immune Infiltration in Hepatocellular Carcinoma.

Liu F, Yin P, Lu L, Yao J, Jiao B
Applied biochemistry and biotechnology 2025 May;197(5):3311-3331

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Repeated administration of esketamine ameliorates mechanical allodynia in mice with chemotherapy-induced peripheral neuropathy: A role of gut microbiota and metabolites.

Luan WW, Gu HW, Qiu D, Ding X, Liu PM, Hashimoto K, Yang JJ, Wang XM
Neurochemistry international 2025 May;185:105961

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Smooth muscle cell Piezo1 is essential for phenotypic switch and neointimal hyperplasia.

Zhang FR, Tang J, Lai Y, Mo SQ, Lin ZM, Lei QQ, Han CC, Zhou AD, Lv XF, Wang C, Ou JS, Zhou JG, Pang RP
British journal of pharmacology 2025 May;182(9):2031-2048

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7 I, a structurally modified sinomenine, exerts dual anti-GBM effects by inhibiting glioblastoma proliferation and inducing necroptosis which further mediates lysosomal cell death.

Yang H, Jiang B, Li W, Du G, Xu F, Zhang Y, Yang Y, Zhang S, Cao W, Li X, Zhang X, Ji T, Wang J
British journal of pharmacology 2025 May;182(10):2310-2331

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Discovery of a potent inhibitor of chaperone-mediated autophagy that targets the HSC70-LAMP2A interaction in non-small cell lung cancer cells.

Dong RF, Qin CJ, Yin Y, Han LL, Xiao CM, Wang KD, Wei RY, Xia YZ, Kong LY
British journal of pharmacology 2025 May;182(10):2287-2309

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Establishment and transcriptomic characteristics of radio-resistant meningioma cell lines.

Yu J, Ren L, Wu T, Hua L, Wang D, Wang Y, Xie Q, Deng J, Gong Y
Journal of neuro-oncology 2025 May;173(1):105-119

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Jiawei Danxuan Koukang and its key component Quercetin intervened in OSF carcinogenesis by inhibiting the AR/eIF5A2 signaling pathway-mediated EMT.

Dai Y, Wang C, Xiao Y, Tan Y, Ye Y, Liu Y, Zeng Q, Tan J
Archives of oral biology 2025 May;173:106194

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Odd-Chain Fatty Acid-Enriched Fats Improve Growth and Intestinal Morphology and Function in Milk Replacer-Fed Piglets.

Duan G, Li M, Zheng C, Wan M, Yu J, Cao B, Yin Y, Duan Y, Cong F
The Journal of nutrition 2025 May;155(5):1298-1310

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NAT10 inhibition alleviates astrocyte autophagy by impeding ac4C acetylation of Timp1 mRNA in ischemic stroke.

Yang L, Li X, Zhao Y, Chen H, Wang C, Wu A, Guo X, Huang Y, Wang Q, Hao L, Li X, Ji Y, Ban J, Wang G, Cao J, Pan Z
Acta pharmaceutica Sinica. B 2025 May;15(5):2575-2592

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Biophysically Optimized Nanofiber-Hydrogel Scaffold Composite Acts as "Bio-Bonsai" for Peripheral Nerve Simulation and Regeneration via Orienting Adipose Derived Stem Cells into Schwann-Like Cell Differentiation.

Qin Y, Chen B, Hu Y, Zhang X, Wang Z, Ma C, Yang R, Wang B, Li F, Niu S, Han Y, Lu D
Advanced healthcare materials 2025 May;14(13):e2404178

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Integrated multi-omics characterization of neuroblastoma with bone or bone marrow metastasis.

Huang K, Yang L, Ma Y, Cao L, Li S, Zhao Z, Zhou J, Wang S
Genes & diseases 2025 May;12(3):101511

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PPY-Induced iCAFs Cultivate an Immunosuppressive Microenvironment in Pancreatic Cancer.

Cao M, Peng W, Cheng B, Wang R, Chen W, Liu L, Huang H, Chen S, Cui H, Liang J, Zhou Q, Xiong S, Bai S, Liu L, Zhao Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(20):e2413432

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Conjugated Lithocholic Acid Activates Hepatic TGR5 to Promote Lipotoxicity and MASLD-MASH Transition by Disrupting Carnitine Biosynthesis.

Lian S, Lu M, Jiajing L, Zhang B, Fang Y, Wang X, Zheng M, Ni Y, Xu G, Yang Y, Jiang R
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(20):e2410602

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Syntaxin 17 Translocation Mediated Mitophagy Switching Drives Hyperglycemia-Induced Vascular Injury.

Luo A, Wang R, Gong J, Wang S, Yun C, Chen Z, Jiang Y, Liu X, Dai H, Liu H, Zheng Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(19):e2414960

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ERK pathway reactivation prevents anthrax toxin lethality in mice.

Liu J, Zuo Z, Ewing M, Cao Q, Cao L, Li Q, Finkel T, Leppla SH, Liu S
Nature microbiology 2025 May;10(5):1145-1155

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Expression of BDNF in the Cortex and Hippocampus of Mice With Middle Cerebral Artery Occlusion.

Hwang HI, Chung YY, Shin HK, Kim DJ, Jun YH
In vivo (Athens, Greece) 2025 May-Jun;39(3):1414-1421

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Inactivation of TACC2 epigenetically represses CDKN1A and confers sensitivity to CDK inhibitors.

Lin ZR, Xia TL, Wang MY, Zhang LJ, Liu YM, Yuan BY, Zhou AJ, Yuan L, Zheng J, Bei JX, Lin DX, Zeng MS, Zhong Q
Med (New York, N.Y.) 2025 May 9;6(5):100568

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Hippocampal NLRP1 inflammasome mediates anxiety-like behavior in mice with hypothyroidism.

Cheng YW, Zou ZH, Lou CL, Tong MR, Li JK, Zhu WH, Lu YL, Zhu DF, Xu Q, Xu YX
Scientific reports 2025 May 9;15(1):16176

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PLEKHA4 is transcriptionally regulated by HOXD9 and regulates glycolytic reprogramming and progression in glioblastoma via activation of the STAT3/SOCS-1 pathway.

Zhang D, Wang X, Xiao M, Ma S, Li S, Jia W
Oncogenesis 2025 May 9;14(1):15

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The mechanism underlying the protective effect of Rebaudioside B against acute lung injury using a network pharmacology-based strategy.

Wu X, Liu X, Li J, Xiong R, Wu H, Huang J, Mei X
International immunopharmacology 2025 May 8;154:114507

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Impact of chronic hyperglycemia and high-fat diet on Alzheimer's disease-related pathology in CX3CR1 knockout mice.

Ortiz AA, Murtishaw AS, Beckholt M, Salazar AM, Osse AML, Kinney JW
Metabolic brain disease 2025 May 7;40(5):197

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Melatonin alleviates sepsis-induced acute lung injury by inhibiting necroptosis via reducing circulating mtDNA release.

Peng Y, Xu J, Wei L, Luo M, Chen S, Wei X, Luo S, Su Z, Wang Z
Molecular medicine (Cambridge, Mass.) 2025 May 7;31(1):176

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IKZF1 as a potential therapeutic target for dendritic cell-mediated immunotherapy in IgA nephropathy.

Peng F, Sheng C, He J, Zhou Y, Qu Y, Duan S, Zhao Y, Xia J, Wu J, Cai G, Wu L, Zhang C, Chen X
Cell communication and signaling : CCS 2025 May 7;23(1):216

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Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion.

Zhang W, Ji C, Li X, He T, Jiang W, Liu Y, Wu M, Zhao Y, Chen X, Wang X, Li J, Zhang H, Wang J
Nature communications 2025 May 7;16(1):4259

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Extracellular vesicles derived from bone marrow mesenchymal stem cells regulate SREBF2/HMGB1 axis by transporting miR-378a-3p to inhibit ferroptosis in intestinal ischemia-reperfusion injury.

Liu Z, Zhao Z, Xiao Z, Li M, Wang X, Huang Y, Li Y
Cell death discovery 2025 May 7;11(1):223

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Antibody Binding and Neutralizing Targets within the Predicted Structure of the Poxvirus Multiprotein Entry-Fusion Complex.

Yu H, Resch W, Cotter CA, Xiao W, Karamanolis T, Belghith AA, Ignacio MA, Earl PL, Cohen GH, Moss B
bioRxiv : the preprint server for biology 2025 May 7;

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Paclitaxel alleviates spinal cord injury via activation of the Wnt/β-catenin signaling pathway.

Chen Z, Wo D, Wu C, Ma E, Peng J, Zhu W, Ren DN
Molecular medicine (Cambridge, Mass.) 2025 May 6;31(1):172

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Gestational Exposure to Black Phosphorus Nanoparticles Induces Placental Trophoblast Dysfunction by Triggering Reactive Oxygen Species-Regulated Mitophagy.

Zhang C, Xiao L, Fang Z, Li S, Fan C, You R, Wang C, Li A, Wang X, Zhang M
ACS nano 2025 May 6;19(17):16517-16533

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Investigating the mechanisms by which low NAT1 expression in tumor cells contributes to chemo-resistance in colorectal cancer.

Yuan Z, Fang K, Miao X, Zhang Y, Gu M, Xu W, Li H, Zhu D, Zhou J, Sun J, Gu X
Clinical epigenetics 2025 May 6;17(1):77

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ZIP8 modulates ferroptosis to drive esophageal carcinoma progression.

Yang Z, Zhao K, Li X, Yanzhang R, Zhang H, Yu Y, Yan M, Fang S, Li T, Li H, Chu X, Han S, Zhang Z, Teng J, Jin G, Guo Z
Cell death & disease 2025 May 6;16(1):366

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PCSK9 promotes progression of anaplastic thyroid cancer through E-cadherin endocytosis.

Zhang Y, Su W, Ji X, Yang Z, Guan Q, Pang Y, Zhong L, Wang Y, Xiang J
Cell death & disease 2025 May 6;16(1):362

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Methyltransferase-like 3-catalysed N6-methyladenosine methylation facilitates the contribution of vascular smooth muscle cells to atherosclerosis.

Dong Z, Jin Y, Shen Y, Huang J, Tan J, Feng Q, Gong Z, Zhu S, Chen H, Yu F, Li W, Jia Y, Kong W, Fu Y
Cardiovascular research 2025 May 6;121(4):568-584

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Alpha-lipoic acid alleviated intermittent hypoxia-induced myocardial injury in mice by promoting autophagy through Nrf2 signaling pathway.

Wang X, Song SM, Lu WQ, Zhao Y, Lv RJ, He Y, Dong N, Yu Q, Yue HM
European journal of pharmacology 2025 May 5;994:177380

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Heat stress enhances the expression of METTL3 to mediate N6-methyladenosine modification of SOS2 and NLRP3 inflammasome activation in boar Sertoli cells.

Zhang X, Tang Y, Wang J, Yang M, Jiang J, Xue H, Wang Y, Zhang J, Wang X
Journal of hazardous materials 2025 May 5;488:137432

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Ceramide mediates cell-to-cell ER stress transmission by modulating membrane fluidity.

Huo Y, Liu X, Lu C, Li T, Yang Z, Xu F, Chen S, Yin K, Wang L
The Journal of cell biology 2025 May 5;224(5)

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SMYD2 Promotes Renal Tubular Cell Apoptosis and Chronic Kidney Disease Following Cisplatin Nephrotoxicity.

Zuo S, Yuan H, Li X, Chen M, Peng R, Chen S, Zou X, Yang Y, Long H, Liu Z, Wang T, Guo B, Liu L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70651

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Effect of intraarticular human umbilical cord mesenchymal stem cells transplantation on cartilage degradation and matrix metalloproteinases in OA rat model.

Li Y, Han Q, Chen S, Huang W, Chen Y, Wu Z, Tan F, Liu M, Zou J
BMC musculoskeletal disorders 2025 May 31;26(1):538

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Iron metabolism disorder and artesunate inhibiting tumor growth by inducing ferroptosis in Lymphangioleiomyomatosis.

Bai W, Zhang S, Hua L, Wang D, Guo M, Wang X, Zhou Y, Cao Y, Wang Q, Zhang N, Xue B, Xie M
Respiratory research 2025 May 30;26(1):204

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Plasma Proteomic Profiling Reveals ITGA2B as A Key Regulator of Heart Health in High-altitude Settlers.

Wang Y (王一豪), Shen P (沈磐), Wu Z (伍振辉), Tu B (涂博丹), Zhang C (张程), Zhou Y (周永强), Liu Y (刘溢思), Wang G (王贵宾), Bai Z (柏志杰), Tang X (汤响林), Lai C (赖成材), Lu H (吕海涛), Zhou W (周维), Gao Y (高月)
Genomics, proteomics & bioinformatics 2025 May 30;23(2)

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The mechanism of telomerase Cajal body protein 1 regulating senescence of mouse bone marrow mesenchymal stem cells.

Lin SQ, Tian N, Yao X, Pan XH, Li ZA, Wang Q, Gao J, Zhao XL, Ruan GP
Stem cell research & therapy 2025 May 30;16(1):267

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Cbl-b inhibitor NX-1607 activates MAPK/ERK signaling pathway and enhances T-cell activation.

Zhu W, Lu S, Jia L, Liu B, Song S, Bao X, Yu T, Zhang Y, Miao Z, He J
Journal for immunotherapy of cancer 2025 May 30;13(5)

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Venetoclax synergizes with Wnt/β-catenin inhibitor C-82 in acute myeloid leukemia by increasing the degradation of Mcl-1 protein.

Pan M, Jiao C, Sun M, Jin D, Wang Y, Wu H, Zhang Y, Chen E, Su B, Zhou J, Liu X, Ge J
Cancer cell international 2025 May 29;25(1):197

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Reln-Dab1 pathway mitigates retinal ganglion cell apoptosis in retinal ischemia-reperfusion injury.

Xu N, Li Z, Zeng X, Jiang Y, Sun T, Liu S, Li N, Li Z, Huang Y, Wang L
Cell death & disease 2025 May 29;16(1):423

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Pentose phosphate recycling driven by Gli1 contributes to chemotherapy resistance in cancer cells.

Hu Q, Jiang C, Qin Y, Li B, Wang J, Wang T, Ji S, Ye Z, Dang Q, Liu M, Yu X, Xu X
Cancer letters 2025 May 28;618:217633

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Acetylation-induced degradation of ECHS1 enhances BCAA accumulation and proliferation in KRAS-mutant colorectal cancer.

Li Z, Liu Z, Lin M, Pan H, Liu Y, Liu Y, Xie Y, Zhang J, Guan S, Li Y, Zhu M, Fang Y, Shen Z, Deng H
Journal of experimental & clinical cancer research : CR 2025 May 28;44(1):164

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Ginsenoside Rg1 attenuates T2DM-induced renal damage and fibrosis by inhibiting TRPC6-ChREBP-TXNIP signaling.

Zhang H, Liang H, Fan L, Zhu X, Ji P, Su Y, Li W, Li W
Journal of ethnopharmacology 2025 May 28;348:119863

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Xiao-Chai-Hu granule alleviates influenza virus-induced pneumonia by regulating TLR4-PI3K-Akt/p38 MAPK-NF-κB pathways.

Li JJ, Chen ZH, Liang WT, Yang YD, Xie TY, Chen DJ, Yang X, Wu PL, Liang XW, Zou HP, Zhang JH, Shi W, Zhang FX
Journal of ethnopharmacology 2025 May 28;348:119760

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Wuwei Shaji powder alleviates OVA-induced allergic asthma by protecting bronchial epithelial cells from ferroptosis via the S-sulfhydration of Keap1.

Zhao H, Zhang H, Shi J, Liu Y, Yu J, Yang Y, Weng J, Song Z, Zhou R, Min H, Yao J, Wang M, Zhang Z
Journal of ethnopharmacology 2025 May 28;348:119649

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ACE2 from Pipistrellus abramus bats is a receptor for HKU5 coronaviruses.

Catanzaro NJ, Wu Z, Fan C, Jefferson V, Abdelgadir A, Schäfer A, Yount BL, Bjorkman PJ, Baric R, Letko M
Nature communications 2025 May 28;16(1):4932

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NUDT21 lactylation reprograms alternative polyadenylation to promote cuproptosis resistance.

Lin J, Yin Y, Cao J, Zhang Y, Chen J, Chen R, Zou B, Huang C, Lv Y, Xu S, Yang H, Lin P, Xie D
Cell discovery 2025 May 28;11(1):52

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Combining xQTL and genome-wide association studies from ethnically diverse populations improves druggable gene discovery.

Lorincz-Comi N, Song W, Chen X, Paz IR, Hou Y, Zhou Y, Xu J, Martin W, Barnard J, Pieper AA, Haines JL, Chung M, Cheng F
Research square 2025 May 28;

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LSM12 promotes the lung squamous cell carcinoma progression through mediating alternative splicing of ARRB1.

Wu L, Zhang F, Chen H, Zhao G
Communications biology 2025 May 27;8(1):814

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GATA1-mediated Notch signaling augment antitumor immunity of CD11b(+)CD27(-) natural killer cells maturation via BCL9/β-catenin signal.

Yang F, Li A, Zhu Y, Zhou Y, Tian E, Yang M, Zhou Q, Yang D, Wang MW, Mei F, Zhu D
Cell reports 2025 May 27;44(5):115708

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H3K18 lactylation-mediated Ythdf2 activation restrains mouse female germline stem cell proliferation via promoting Ets1 mRNA degradation.

Wu Y, Xu B, Peng Y, Lin S, Du W, Liu R, Zhang S, Wu J, Zou K, Zhao X
Clinical epigenetics 2025 May 27;17(1):84

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Icariin alleviates cardiomyocyte pyroptosis through AMPK-NLRP3 pathway to ameliorates diabetic cardiomyopathy.

Cai Z, Sun F, Wang Q, Li S, Wang L, Li H, Su Y, Yang H, Dong B
International immunopharmacology 2025 May 27;156:114690

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Xiasangju alleviates hepatic insulin resistance in db/db mice via AMPK pathway: Mechanisms and active components study.

An Y, Zhao H, He C, Shi L, Su X, Zhang H, Huang Y, Shan Z, Wang M, Du Y, Xie J, Zhao Y, Yang Y, Huang Z, Wan A, Zhao Y, Zhao B
International immunopharmacology 2025 May 27;156:114675

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Scutellarin suppresses ovarian cancer progression by targeting METTL5.

Ding L, Luo C, Weygant N, Chen W, Ru D, Lai Y, Wang Y, Li H
Scientific reports 2025 May 27;15(1):18472

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Integrating bioinformatics and machine learning to identify biomarkers of branched chain amino acid related genes in osteoarthritis.

ZhaYang XZ, Chen YX, Hua WD, Bai ZL, Jin YP, Zhao XW, Liu QF, Meng ZD
BMC musculoskeletal disorders 2025 May 26;26(1):517

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Provoking tumor disulfidptosis by single-atom nanozyme via regulating cellular energy supply and reducing power.

Yu W, Jin D, Zhang Y, Wang S, Yu J, Liu M, Dai Y, Yin Y, Cheng J, Liu Y
Nature communications 2025 May 26;16(1):4877

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Multi-omics analysis identifies LANCL2 as a potential biomarker for the diagnosis and prognosis of gastric cancer.

Fang X, Liu M, Ren Q, Li R, Wu G, Yuan H, Zheng Y, Gou X, Wang Y, Zhou Y
Scientific reports 2025 May 25;15(1):18231

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High-frequency repetitive transcranial magnetic stimulation attenuates white matter damage and improves functional recovery in rats with ischemic stroke.

Luo C, Tang X, Shao H, Guo F
Neuroscience 2025 May 24;575:48-56

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MiR-493-5p functions as a tumour suppressor in head and neck squamous cell carcinoma progression by targeting HIF-1α.

Liu J, Tian R, Chen X, Song Q, Sun C, Li D, Fang Y, Lv S, Li Y, Song X
Discover oncology 2025 May 24;16(1):899

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hnRNPL phase separation activates PIK3CB transcription and promotes glycolysis in ovarian cancer.

Qin F, Wang Y, Yang C, Ren Y, Wei Q, Tang Y, Xu J, Wang H, Luo F, Luo Q, Luo X, Liu X, Yang D, Zuo X, Yang Y, Cheng C, Xu J, Wang W, Liu T, Yi P
Nature communications 2025 May 24;16(1):4828

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Low level of lactate and trophoblast dysfunction mediated by SNAI1/PDK1 contributes to miscarriage.

Gou R, Yin FF, Han TT, Yin XJ, Zhong X, Zhang XH
Placenta 2025 May 23;165:33-41

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Homocysteine induces endometrial ferroptosis via MAPK pathway in recurrent pregnancy loss.

Yang X, Wang L, Wang R, Ding N, He Y, Wang F
Placenta 2025 May 23;165:148-161

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Discovery of P11-2: A Potent First-in-Class MNK1-Targeting PROTAC Degrader for the Treatment of Cancer.

Yang Z, Liu Y, Liao Z, Chen L, Liang Z, Zhang L, Li Z
Journal of medicinal chemistry 2025 May 22;68(10):10092-10110

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CDK2 inhibition produces a persistent population of polyploid cancer cells.

Tyutyunyk-Massey L, Chen Z, Liu X, Kawakami M, Harned A, Ng Y, Luke B, Okpechi SC, Ogunlade B, Alfaro Y, Weigert R, Narayan K, Liu X, Dmitrovsky E
JCI insight 2025 May 22;10(10)

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The dimeric conformation of PRRSV nsp1α is important for its ability to regulate viral RNA synthesis.

Li Q, Hu J, Jiao X, Shi J, Li C, Li Y
Veterinary research 2025 May 21;56(1):105

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Metformin reverses 5-FU resistance induced by radiotherapy through mediating folate metabolism in colorectal cancer.

Wang S, Lin Y, Zhao Q, Chen H, Du S, Zeng Z
Molecular medicine (Cambridge, Mass.) 2025 May 21;31(1):199

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Integrative Analysis of Immune- and Metabolism-Related Genes Identifies Robust Prognostic Signature and PYCR1 as a Carcinogenic Regulator in Clear Cell Renal Cell Carcinoma.

Zhao G, Ding J, Ma J, Jiang Y, Wang Y, Wang S, Li N
International journal of molecular sciences 2025 May 21;26(10)

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Tie2-expressing monocytes/macrophages promote angiogenesis in chronically ischaemic brain tissue.

Tai C, Ling C, Yang Y, Zhang B, Sun J, Mo N, Sun T, Huang L, Yao C, Wang H, Chen C
Cell & bioscience 2025 May 21;15(1):62

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Lnc-DARVR/miR-365-1-5p/LAMB1 axis regulates rotavirus replication via the complement C3 pathway.

Song X, Yao L, Li Y, Wang J, Lu C, Li J, Leng Q, Tang X, Hu X, Wu J, Chen R, Lin X, Ye J, Kuang X, Zhang G, Sun M, Zhou Y, Li H
Journal of virology 2025 May 20;99(5):e0211424

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Syntaxin-6 restricts SARS-CoV-2 infection by facilitating virus trafficking to autophagosomes.

Sun H, Yang Q, Zhang Y, Cui S, Zhou Z, Zhang P, Jia L, Zhang M, Wang Y, Chen X, Pei R
Journal of virology 2025 May 20;99(5):e0000225

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Liquiritigenin protects against cadmium-induced testis damage in mice by inhibiting apoptosis and activating androgen receptor.

Yuan S, Guo J, Yang B, Huang AX, Hu S, Li Y, Chen J, Yuan B, Yang J
Biochemical and biophysical research communications 2025 May 20;759:151642

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[Villin-like protein VILL suppresses proliferation of nasopharyngeal carcinoma cells by interacting with LMO7 protein].

Zeng Y, Li J, Huang Z, Zhou Y
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2025 May 20;45(5):954-961

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Toxoplasma calcium-dependent protein kinases 3 mediates M1 macrophage polarization by targeting host Arginase-1.

An R, Liu F, Dai N, Li F, Liu X, Cai H, Chen L, Du J
Parasites & vectors 2025 May 20;18(1):181

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Modulation of host ATP levels by secreted bacterial effectors.

He C, Li C, Liu Y, Chen TT, Li C, Chu X, Liu S, Wang L, Zhang Y, Ouyang S, Fu J, Song L, Luo ZQ
Nature communications 2025 May 20;16(1):4675

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Arginine Deprivation Induces Quiescence and Confers Vulnerability to Ferroptosis in Colorectal Cancer.

Lin Y, Zhang Y, Huang T, Chen J, Li G, Zhang B, Xu L, Wang K, He H, Chen H, Liu D, Guo S, He X, Lan P
Cancer research 2025 May 2;85(9):1663-1679

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HIF1A Regulates Rhbg Expression to Enhance Ammonia Excretion in Amur Ide (Leuciscus waleckii) Under Extreme Alkaline Conditions.

Zhao X, Zhang Y, Li S, Bai S, Zhang W, Xu Y, Chang Y
Biology 2025 May 2;14(5)

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Quercetin Alleviates Breast Cancer-Related Depression by Inhibiting Neutrophil Extracellular Traps via Inhibition of Sphingosine 1-Phosphate/Sphingosine 1-Phosphate Receptor Axis.

Zhu Q, Tao Y, Han Y, He Y, Fu Y, Yang H, Chen Y, Shi Y
Phytotherapy research : PTR 2025 May 2;

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Gut microbial conversion of dietary elderberry extract to hydrocinnamic acid improves obesity-associated metabolic disorders.

Alqudah S, DeLucia B, Osborn LJ, Markley RL, Bobba V, Preston SM, Thambidurai T, Nia LH, Fulmer CG, Sangwan N, Nemet I, Claesen J
bioRxiv : the preprint server for biology 2025 May 18;

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DNA hypermethylation of PLTP mediated by DNMT3B aggravates vascular dysfunction in diabetic retinopathy via the AKT/GSK3β signaling pathway.

Cai C, Gu C, Meng C, Wang Y, Wei Q, He S, Lai D, Wang X, Wang T, Qiu Q
Clinical epigenetics 2025 May 17;17(1):82

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Hyperandrogenism triggers mtDNA release to participate in ovarian inflammation via mPTP/cGAS/STING in PCOS.

Cai J, Zhu Q, Xiang Y, Weng L, Liang N, Hong X, Xue M, Ge H
iScience 2025 May 16;28(5):112391

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Iron Mediates Radiation-Induced Glioblastoma Cell Diffusion.

Owusu SB, Ekanayake AB, Tivanski AV, Petronek MS
International journal of molecular sciences 2025 May 16;26(10)

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Paeoniflorin alleviated STZ-induced diabetic retinopathy via regulation of the PDI/ADAM17/MerTK pathway.

Qi X, Guo H, Xia X, Liu Y, Qiu S, Lin T, He W, Jin L, Cheng J, Hao L, Liu W, Hu H
International immunopharmacology 2025 May 16;155:114571

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Overexpression of Tgm2 in Chinese Hamster Ovary Cells Enhances Recombinant Monoclonal Antibody Expression and Promotes Cell Proliferation through Reduction of Apoptosis.

Zhang HJ, Zhao Q, Zhang M, Yang LL, Abiti J, Han MM, Gao YP, Lu JT, Wang JN, Ji MY, Zhang X, Wang W, Qiu LL, Wang XY, Wang TY, Jia YL
ACS synthetic biology 2025 May 16;14(5):1802-1812

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Prkra dimer senses double-stranded RNAs to dictate global translation efficiency.

Lu T, Ma P, Fang H, Chen A, Xu J, Kuang X, Wang M, Su L, Wang S, Zhang Y, Wang J, Yang B, Shi DL, Zhou Y, Gong Q, Liu X, Mao B, Shao M
Molecular cell 2025 May 15;85(10):2032-2047.e9

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De Novo Serine Synthesis Is a Metabolic Vulnerability That Can Be Exploited to Overcome Sunitinib Resistance in Advanced Renal Cell Carcinoma.

Teisseire M, Sahu U, Parola J, Tsai MC, Vial V, Durivault J, Grépin R, Cormerais Y, Molina C, Gouraud A, Pagès G, Ben-Sahra I, Giuliano S
Cancer research 2025 May 15;85(10):1857-1873

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Bioinformatics exploration of SPHKAP's role in IDH-mutant glioma involving energy metabolism, prognosis, and immune modulation.

Liang X, Tan S, Chen Y, Wei C, Qin Z
Journal of neuroimmunology 2025 May 15;402:578570

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Orai1 Participates in Coronary Artery Dysfunction Caused by Hypertension via Regulating Smooth Muscle Cell Phenotype Transformation.

Wang H, Liang MY, Cai YJ, Deng CY, Yang H, Mai LP, Zhang MZ, Kuang SJ, Rao F, Xu JS
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 15;39(9):e70576

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Unraveling the impact of micro- and nano-sized polymethyl methacrylate on gut microbiota and liver lipid metabolism: Insights from oral exposure studies.

Zheng PC, Pan XQ, Zhou YJ, Lai KP, Li R, Zhang XX
Environmental pollution (Barking, Essex : 1987) 2025 May 15;373:126157

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Pharmacological and genetic inhibition of BTK ameliorates vascular degeneration, dissection, and rupture.

Li S, Liu G, Cheng S, Li X, Weng X, Yang J
Life sciences 2025 May 15;369:123533

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Structural characterizations and antiaging activities of hydrolyzed low-molecular-weight polysaccharides from Polygoni Multiflori Radix Praeparata.

Xu W, Li XJ, Zhong YS, He JQ, Xie W, Kang YK, Ying HZ, Yu CH
Carbohydrate polymers 2025 May 15;356:123381

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PAX translocations remodel mitochondrial metabolism through altered leucine usage in rhabdomyosarcoma.

Kalita B, Martinez-Cebrian G, McEvoy J, Allensworth M, Knight M, Magli A, Perlingeiro RCR, Dyer MA, Stewart E, Dynlacht BD
Cell 2025 May 15;188(10):2757-2777.e22

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Galectin-3 activates microglia and promotes neurological impairment via NLRP3/pyroptosis pathway following traumatic brain injury.

Sun Y, Gao SQ, Wang X, Li T, Han YL, Miao SH, Zhao R, Zheng XB, Qiu JY, Jin WX, Gao CC, Zhou ML
Brain research 2025 May 15;1855:149560

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Effects of Diethylstilbestrol on the Structure and Function of the Spleen in Male Golden Hamsters.

Li J, Xu R, Wang Q, Bai X, Su Y, Chen Y, Cao J
Toxics 2025 May 15;13(5)

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Multi-Omics Unveils Inflammatory Regulation of Fermented Sini Decoction Dregs in Broilers Infected with Avian Pathogenic Escherichia coli.

Mo S, Fang X, Xiao W, Huang B, Li C, Yang H, Wu Y, Wang Y, Ma H
Veterinary sciences 2025 May 15;12(5)

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An ATM-PPM1D Circuit Controls the Processing and Restart of DNA Replication Forks.

Cao Y, Wang Y, Badar J, Palek M, Jaber K, Faça VM, Huang TC, Çelik E, Macurek L, Smolka MB
bioRxiv : the preprint server for biology 2025 May 15;

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RNA-binding protein gene NOP58 exhibits crucial prognostic and therapeutic value in Ewing sarcoma.

Geng Y, Yang L, Shao R, Xu T, Zhang L
Hereditas 2025 May 14;162(1):76

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Baicalin mitigates alcoholic-associated liver disease via SOCS1-driven reprogramming of macrophages.

Huang S, Wang Y, Wen J, Ji W, Zeng Q, Deng K, Li M, Kuang S, Zhang W, Chan M, Zhou C, Lv Z, Huang S
Chinese medicine 2025 May 13;20(1):63

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Harnessing Kupffer Cell Metabolic Rewiring: Rapamycin-Gliadin Nanoparticle as a Pivotal Strategy for Immune Tolerance in Celiac Disease.

Jiang X, Wang M, Zou R, Fu M, Fan W, Wang Y, Dai C, Swapnil Z, Wang W, Wu H, Xie K, Liu L, Wang Y, Fan Z, Zhao L
ACS nano 2025 May 13;19(18):17462-17477

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FAK regulates trophoblast functions of invasion and proliferation through Rap1 pathway in early-onset preeclampsia.

Wang T, Tong H, Chen R, Jiang Y, Zhang C, Qi H, Zhang X
Biochemical and biophysical research communications 2025 May 12;763:151788

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Circular RMST cooperates with lineage-driving transcription factors to govern neuroendocrine transdifferentiation.

Teng M, Guo J, Xu X, Ci X, Mo Y, Kohen Y, Ni Z, Chen S, Guo WY, Bakht M, Ku S, Sigouros M, Luo W, Macarios CM, Xia Z, Chen M, Ul Haq S, Yang W, Berlin A, van der Kwast T, Ellis L, Zoubeidi A, Zheng G, Ming J, Wang Y, Cui H, Lok BH, Raught B, Beltran H, Qin J, He HH
Cancer cell 2025 May 12;43(5):891-904.e10

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Huangqin decoction alleviated irinotecan-induced diarrhea by inhibiting endoplasmic reticulum stress through activating AMPK/mTOR-mediated autophagy.

He Y, Feng L, Gao Y, Wang Y, Yang C, Han S, Ren Y, Zhai Y, Nie K
Journal of ethnopharmacology 2025 May 12;347:119790

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Lan-Qin oral liquid alleviates influenza A virus-induced acute lung injury by regulating monocyte-derived macrophages and TLR4-PI3K-AKT-NF-κB signal pathways.

Chen ZH, Li JJ, Liu CJ, Chen DJ, Yang YD, Xie TY, Liang WT, Tu XP, Shi W, Yang X, Chen ZF, Zhang FX
Journal of ethnopharmacology 2025 May 12;347:119787

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Taraxacum mongolicum Hand.-Mazz. extract disrupts the interaction between triple-negative breast cancer cells and tumor-associated macrophages by inhibiting RAC2/NF-κB p65/p38 MAPK pathway.

Li X, Guo Y, Deng X, Jiao Y, Hao H, Dong Q, Sun H, Han S
Journal of ethnopharmacology 2025 May 12;347:119757

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IGF2BP3-mediated m(6)A modification of RASGRF1 promoting joint injury in rheumatoid arthritis.

Geng Q, Jiao Y, Diao W, Xu J, Wang Z, Wang X, Wang Z, Zhao L, Yang L, Wang Y, Deng T, Wang B, Xiao C
Bone research 2025 May 12;13(1):51

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Isorhamnetin Attenuates Isoproterenol-Induced Myocardial Injury by Reducing ENO1 (Alpha-Enolase) in Cardiomyocytes.

Guo Z, Liu S, Hou X, Zhou X, Wang Y, Rong Y, Li X, Yang R, Ma K
Antioxidants (Basel, Switzerland) 2025 May 11;14(5)

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YTHDF1-targeting nanoassembly reverses tumoral immune evasion through epigenetics and cell cycle modulation.

Liu H, Zhang X, Ding F, Pan J, Zhu H, Zhou Z, Sun M
Journal of controlled release : official journal of the Controlled Release Society 2025 May 10;381:113574

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Conditional sequential delivery of ginkgetin and rapamycin orchestrates inflammation and autophagy to alleviate intervertebral disc degeneration.

Chen J, Gan X, Su S, Jiao S, Gong Z, Liu Z, Wu X, Jiang J, Zhang J, Wan J
Journal of controlled release : official journal of the Controlled Release Society 2025 May 10;381:113556

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Intrapleural dual blockade of IL-6 and PD-L1 reprograms CAF dynamics and the tumor microenvironment in lung cancer-associated malignant pleural effusion.

Cheng Q, Zuo X, Wang Z, Lu W, Jiang Y, Liu J, Li X, Xu Q, Zhu S, Liu X, Song Y, Zhan P, Lv T
Respiratory research 2025 May 10;26(1):180

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STAT3-mediated upregulation of TRIM6 promotes hepatocellular carcinoma invasion through the DDX58-Snail1 axis.

Wang Y, Wang J, Huang S, Liu X, Cai Y, Wang T, Zhao H, Lin X, Wang X, Li P
Scientific reports 2025 May 10;15(1):16284

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Autophagy Impairment-Derived SQSTM1 Accumulation Promotes Ferroptosis in Corneal Epithelial Cells Through ACSL4 in Dry Eye.

Zhang R, Liang L, Liao K, Zeng H, Yang X, Wang X, Wang B, Yuan J
Investigative ophthalmology & visual science 2025 May 1;66(5):23

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GW806742X can induce mouse MLKL activation by directly promoting MLKL kinase like domain dimerization.

Yuan F, Zhang Y, Zhu X, Hu H, Nan N, Wang H
Experimental cell research 2025 May 1;448(1):114539

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The influence and mechanisms of exogenous aryl hydrocarbon receptor ligands on the viability of mouse germ cells.

Cheng Y, Yang Y, Chen C, Zhang F, Peng S, Xiao X, Peng Z
Chemico-biological interactions 2025 May 1;412:111478

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Mesenchymal stem cell-derived small extracellular vesicles as a delivery vehicle of oncolytic reovirus.

Uno K, Kubota E, Mori Y, Nishigaki R, Kojima Y, Kanno T, Sasaki M, Fukusada S, Sugimura N, Tanaka M, Ozeki K, Shimura T, Johnston RN, Kataoka H
Life sciences 2025 May 1;368:123489

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Interplay and cooperation between GLI2 and master transcription factors promote progression of esophageal squamous cell carcinoma.

Liu YQ, Zheng ZJ, Fang WK, Li YS, Li C, Yang M, Han DC, Zhou JH, Xie YH, Zhang YY, Kang ZY, Xu YW, Xie JJ
American journal of human genetics 2025 May 1;112(5):1039-1061

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Mechanosensitive ion channel-related genes in hepatocellular carcinoma: Unraveling prognostic genes and their roles in drug resistance and immune modulation.

Huo X, Jiang S, Wu S, Lian Q, Chen H
Liver research (Beijing, China) 2025 Mar;9(1):36-48

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Hsp90 and HIF-1α regulate mitophagy by promoting BNIP3 expression in renal ischemia-reperfusion injury.

Dong Q, Li X, Cheng K
Transplant immunology 2025 Mar;89:102177

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Diagnostic value of TRIM22 in diabetic kidney disease and its mechanism.

Wang Q, Ge Q, Wang J, Wu Y, Qi X
Endocrine 2025 Mar;87(3):959-977

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Melatonin protects aged oocytes from depalmitoylation-mediated quality reduction by promoting PPT1 degradation and antioxidation.

Ma R, Xue M, Ge F, Jueraitetibaike K, Zhao S, Qian Z, He Z, Zhang H, Tang T, Cao C, Li C, Zheng L, Xue T, Dong J, Jing J, Zhong J, Ma J, Yang Y, Huang Y, Ge X, Yao B, Chen L
Redox biology 2025 Mar;80:103510

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Endogenous metabolite N-chlorotaurine attenuates antiviral responses by facilitating IRF3 oxidation.

Yang Y, Wang C, Sun W, Fu Y, Wu X, Zhao C, Song H, Zhao W, Qin Y
Redox biology 2025 Mar;80:103492

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Sivelestat sodium protects against renal ischemia/reperfusion injury by reduction of NETs formation.

Liu Y, Xin Y, Yuan M, Liu Y, Song Y, Shen L, Xiao Y, Wang X, Wang D, Liu L, Liu Y, Luo Y, Huang P, Zhang Q, Zhang W, Li H, Zhou Y, Wang X, Yu K, Wang C
Archives of biochemistry and biophysics 2025 Mar;765:110318

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The protective role of kakkalide in sepsis-induced intestinal barrier dysfunction via inhibition of NF-κB pathway activation.

Xu T, Han J, Wang N, Huan Z, Yao H, Ge X
Journal of clinical biochemistry and nutrition 2025 Mar;76(2):139-147

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FSD1 inhibits glioblastoma diffuse infiltration through restriction of HDAC6-mediated microtubule deacetylation.

Xiao D, Ran H, Chen L, Li Y, Cai Y, Zhang S, Qi Q, Wu H, Zhang C, Cao S, Mi L, Huang H, Qi J, Han Q, Tu H, Li H, Zhou T, Li F, Li A, Man J
Science China. Life sciences 2025 Mar;68(3):673-688

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Curcumin inhibits the activity of ubiquitin ligase Smurf2 to promote NLRP3‑dependent pyroptosis in non‑small cell lung cancer cells.

Xi Y, Zeng S, Tan X, Deng X
International journal of oncology 2025 Mar;66(3)

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17β-Trenbolone Exposure Enhances Muscle Activity and Exacerbates Parkinson's Disease Progression in Male Mice.

Zuo X, Bai HJ, Zhao QL, Zhang SH, Zhao X, Feng XZ
Molecular neurobiology 2025 Mar;62(3):3053-3066

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Urolithin B suppresses phenotypic switch in vascular smooth muscle cells induced by PDGF-BB via inhibiting the PI3K-AKT pathway.

Li S, Zhang Y, Zhang T, Jiang D, Li M, Chen L, Jiang J, Zhang C, Li Q
In vitro cellular & developmental biology. Animal 2025 Mar;61(3):311-319

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Transcription factor SMAD5 upregulates ALG5 to alleviate osteoporosis development by inducing osteogenic differentiation.

Li Z, Liu Y, Wang H, Xu G
Journal of orthopaedics 2025 Mar;61:140-149

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SLC31A1 promotes chemoresistance through inducing CPT1A-mediated fatty acid oxidation in ER-positive breast cancer.

Li X, Ge J, Wan M, Feng T, Li X, Zhang H, Wang Z, Gao Y, Chen M, Pan F
Neoplasia (New York, N.Y.) 2025 Mar;61:101125

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Edaravone inhibits neuronal ferroptosis and alleviates acute Central nervous system injury induced by diquat via enhancement of METTL14-mediated m6A methylation of Aldh1l1.

Wu L, Luo Z, Luo F, Huang T, Cen Y, Rao G, Zhao Z, Ou R, Zhou M
Free radical research 2025 Mar;59(3):274-288

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LncRNA Gm35585 transcriptionally activates the peroxidase EHHADH against diet-induced fatty liver.

Jin M, Lu Q, Xia N, Fan X, Zhang Z, Huang X, Sun L, Zhang L, Jiang Z, Yu Q
Experimental & molecular medicine 2025 Mar;57(3):652-666

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Uncarboxylated osteocalcin induced miR-143-3p targets SP7 and activates PI3K/Akt signaling in TNBC cells to promote invasion and migration.

Du Q, Xu J, Zhang M, Yang J
Translational oncology 2025 Mar;53:102305

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Molecular Mechanism of Ginsenoside Rg3 Alleviation in Osteoporosis via Modulation of KPNA2 and the NF-κB Signalling Pathway.

Zhang X, Huang F, Liu J, Zhou Z, Yuan S, Jiang H
Clinical and experimental pharmacology & physiology 2025 Mar;52(3):e70019

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Restoring Autophagy by Exercise Ameliorates Insulin Resistance Partly via Calcineurin-Driven TFEB Nuclear Translocation.

Wang P, Li J, Li CG, Zhou X, Chen X, Zhu M, Wang H
Clinical and experimental pharmacology & physiology 2025 Mar;52(3):e70010

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Benzyl butyl phthalate promotes ferroptosis in Sertoli cells via disrupting ceruloplasmin-mediated iron balance.

Dong Y, Shu S, Yu X, Chen X, Li Q, Shen X, Yu Y
Toxicology 2025 Mar;512:154078

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The potential role of the SIRT1-Nrf2 signaling pathway in alleviating hidden hearing loss via antioxidant stress.

Zheng Z, Zhang P, Fu Y, Jiang Y, Zhu J, Wang F, Li S, Zhang Z, Chang T, Li T, Zhang M, Ruan B, Wang X
Cell biology international 2025 Mar;49(3):262-276

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The METTL3/TRAP1 axis as a key regulator of 5-fluorouracil chemosensitivity in colorectal cancer.

Kang Q, Hu X, Chen Z, Liang X, Xiang S, Wang Z
Molecular and cellular biochemistry 2025 Mar;480(3):1865-1889

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Inhibition of STRA6 suppresses NSCLC growth via blocking STAT3/SREBP-1c axis-mediated lipogenesis.

Zhou Y, Zhou R, Wang N, Zhao T, Qiu P, Gao C, Chang M, Lin N, Zhang X, Li JZ, Wang Q
Molecular and cellular biochemistry 2025 Mar;480(3):1715-1730

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THRA1/PGC-1α/SIRT3 pathway regulates oxidative stress and is implicated in hypertension of maternal hypothyroid rat offspring.

Guo J, Shi Y, Yu X, Zhao Y, Wei B, Huo M, Lu L, Li L, Gao Q, Sun M
Hypertension research : official journal of the Japanese Society of Hypertension 2025 Mar;48(3):1080-1098

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Dependence of NPPS creates a targetable vulnerability in RAS-mutant cancers.

Xia RX, Zou PC, Xie JT, Tang YB, Gong MM, Fan F, Aihemaiti A, Liu YQ, Shen Y, Zhou BS, Zhu L, Lei HM
Acta pharmacologica Sinica 2025 Mar;46(3):728-739

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Ergothioneine Ameliorates Liver Fibrosis by Inhibiting Glycerophospholipids Metabolism and TGF-β/Smads Signaling Pathway: Based on Metabonomics and Network Pharmacology.

Mao Y, Xie Z, Zhang X, Fu Y, Yu X, Deng L, Zhang X, Hou B, Wang X, Ma M, Ren F
Journal of applied toxicology : JAT 2025 Mar;45(3):514-530

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The Role of PI3K/AKT/HIF-1α Pathway in the Effect of Nano-TiO(2) on Lactate Production in TM4 Cells.

Chang H, Zhao S, Lei Y, Hu Y, Yan Y, Song G
Journal of applied toxicology : JAT 2025 Mar;45(3):492-502

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JAK2/ULK1 axis promotes cervical cancer progression by autophagy induction and SRPK1 phosphorylation.

Duan Q, Wang W, Xiong H, Xiao J, Xiao H, Zhu F, Lu H
Oncogene 2025 Mar;44(9):587-600

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The effects of citalopram and sertraline on adipogenesis and lipogenesis in 3T3-L1 cells.

Bozdag D, Entezari B, Gurer-Orhan H
Toxicology letters 2025 Mar;405:67-75

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Mitochondrial NAD(+) deficiency in vascular smooth muscle impairs collagen III turnover to trigger thoracic and abdominal aortic aneurysm.

Zhang J, Tang Y, Zhang S, Xie Z, Ma W, Liu S, Fang Y, Zheng S, Huang C, Yan G, Abudupataer M, Xin Y, Zhu J, Han W, Wang W, Shen F, Lai H, Liu Y, Ye D, Yu FX, Xu Y, Pan C, Wang C, Zhu K, Zhang W
Nature cardiovascular research 2025 Mar;4(3):275-292

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UFMylation Modulates OFIP Stability and Centrosomal Localization.

Yang M, Zhao Z, Di J, Dong D, Li D, Ran J
Journal of clinical laboratory analysis 2025 Mar;39(6):e70004

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Berberine Inhibits Migration and Apoptosis of Rat Podocytes in Diabetic Nephropathy via the Novel lncRNA LOC102549726 Related Pathway.

Wang C, Wu H, Xie Y, Wang J, Huang L, Ni X, Deng S, Zhang Y, Chen X, Zhang H, Yuan S, Tang L
Phytotherapy research : PTR 2025 Mar;39(3):1615-1631

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Biological mechanism and functional verification of key genes related to major depressive disorder and type 2 diabetes mellitus.

Fang T, Shen N, Shi Z, Luo W, Di Y, Liu X, Ma S, Wang J, Hou S
Mammalian genome : official journal of the International Mammalian Genome Society 2025 Mar;36(1):66-82

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LDH nanoparticles-doped cellulose nanofiber scaffolds with aligned microchannels direct high-efficiency neural regeneration and organized neural circuit remodeling through RhoA/Rock/Myosin II pathway.

Pang X, Zhang T, Li J, Yu L, Liu Z, Liu Y, Li L, Cheng L, Zhu R
Biomaterials 2025 Mar;314:122873

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BTG3 inhibits porcine epidemic diarrhea virus replication by promoting viral S2 protein degradation through the autophagy and proteasome pathways.

Zhu Q, Liu T, Qin W, Yang X, Tong W, Yu H, Zheng H, Tong G, Shan T, Zhang Y, Liu X, Kong N
Veterinary microbiology 2025 Mar;302:110402

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Glaesserella parasuis serotype 5 promotes pyroptosis via degrading Caveolin-1 in 3D4/21 cells.

Lin H, Zhang J, Wang Q, Zhou H, Fan H
Veterinary microbiology 2025 Mar;302:110393

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The MCM6-c-Myc positive feedback loop mediates bladder cancer progression and cisplatin resistance.

Wang J, Li X, Zhao L, Fan X, Cao J, Wang S, Li K, Wang H, Zhang Y, Wang H, Xu C, Ding L, Che T, Chen S, Yang L
International journal of biological macromolecules 2025 Mar;296:139777

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Structural characterization of an apple polysaccharide and its anti-inflammatory effect through suppressing TLR4/NF-κB signaling.

Ma S, Zhang R, Li L, Wang J, Zheng M, Guo X, Miao S, Quan W, Liu W, Shi X
International journal of biological macromolecules 2025 Mar;296:139760

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Decorin-mediated dermal papilla cell-derived exosomes regulate hair follicle growth and development through miR-129-2-3p/SMAD3/TGF-β axis.

Li J, Zhao B, Yu Y, Bao Z, Zheng F, Cai J, Chen Y, Wu X
International journal of biological macromolecules 2025 Mar;295:139292

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Preparation, characterization, and stability of selenium nanoparticles decorated with Mori Fructus polysaccharide and its protective effects in bisphenol A-induced Sertoli cells.

Cao M, Qian Y, Sun Z, Liu S, Zheng R, Zhao L, Chen G
International journal of biological macromolecules 2025 Mar;294:139463

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DDR1 Targeting HOXA6 Facilitates Bladder Cancer Progression via Inhibiting Ferroptosis.

Xie X, He H, Zhang N, Wang X, Rui W, Xu D, Zhu Y, Tian M, He W
Journal of cellular and molecular medicine 2025 Mar;29(6):e70410

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p16INK4a Deletion Alleviated Obesity-Associated Kidney Fibrosis by Regulating Metabolic Reprogramming and the Inflammasome Pathway.

Liu Q, Wang F, Du Y, Liu Y, Zhang Z, Zhang X, Li J, Huang G, Liu F, Li B, Xiao W, Sui C, Bao N, Zhuang R, Gao C, Wang X, Gu X
Journal of cellular and molecular medicine 2025 Mar;29(5):e70444

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Overexpression of miR‑424‑5p reduces cisplatin resistance by downregulating SMURF1 in gastric cancer.

Wang D, Cui H, Yan Y, Fu W, Lu L
Oncology letters 2025 Mar;29(3):143

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PDZRN3 regulates adipogenesis of mesenchymal progenitors in muscle.

Iida H, Kawai-Takaishi M, Miyagawa Y, Takegami Y, Uezumi A, Honda T, Imagama S, Hosoyama T
Regenerative therapy 2025 Mar;28:473-480

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The NFATC2/Nrf2 cascade regulates spinal cord ischemia-reperfusion injury by controlling inflammation, apoptosis and oxidative stress.

Li K, Lu L, Yao X, Wu Z, Sun P, Wen X, Li X, Wang K, Yin X
Regenerative therapy 2025 Mar;28:126-133

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DSTYK phosphorylates STING at late endosomes to promote STING signaling.

Dong H, Zhang H, Song P, Hu Y, Chen D
EMBO reports 2025 Mar;26(6):1620-1646

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STIM1-mediated NFAT signaling synergizes with STAT1 to control T-bet expression and T(H)1 differentiation.

Zhong L, Wang YH, Kahlfuss S, Jishage M, McDermott M, Yang J, Tao AY, Hu K, Noyer L, Raphael D, Patel D, Knight TE, Chitlur M, Machaca K, Feske S
Nature immunology 2025 Mar;26(3):484-496

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Investigation of the role and mechanism of dapagliflozin in mitigating renal injury in rats afflicted with diabetic kidney disease.

Wang H, Zhao X, Wang X, Gong Y, Li S, Gu Y, He B, Wang J
Biochemical pharmacology 2025 Mar;233:116795

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5,7-Dihydroxy-4-Methylcoumarin enhances osteogenesis and ameliorates osteoporosis via the AKT1 pathway.

Diao H, Yang H, Yu B, Fan Y, Li S, Fan J, Xiao D, Zhao Y, Guo M, Zhang Y, Huang S, Tang Q, Li SS, Sun T, Jin X
Biochemical pharmacology 2025 Mar;233:116752

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Fibrinogen degradation products exacerbate alpha-synuclein aggregation by inhibiting autophagy via downregulation of Beclin1 in multiple system atrophy.

Liu H, Yu R, Zhang M, Zheng X, Zhong L, Yang W, Luo Y, Huang Z, Zheng J, Zhong H, Wei X, Zheng W, Yu Y, Wang Q
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2025 Mar;22(2):e00538

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Butyrate-engineered yeast activates Nppa and Sgcg genes and reduces radiation-induced heart damage via the gut-heart axis.

Wu J, Ji K, Kang G, Zhang M, Wang J, Wang L, Gao M, Jia X, Lu X, Wang Y, Gao X, Guo Y, Zhu Z, Wang Q, Zhao Z, Liu Q, Huang H
Pharmacological research 2025 Mar;213:107642

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Deciphering melanophagy: role of the PTK2-ITCH-MLANA-OPTN cascade on melanophagy in melanocytes.

Park NY, Jo DS, Park HJ, Bae JE, Kim YH, Kim JB, Lee HJ, Kim SH, Choi H, Lee HS, Yoshimori T, Lee DS, Lee JA, Kim P, Cho DH
Autophagy 2025 Mar;21(3):664-673

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Boric Acid Alleviates Lipopolysaccharide-Induced Acute Lung Injury in Mice.

Zhang X, Wang G, Chen S
Biological trace element research 2025 Mar;203(3):1494-1501

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Sacubitril/valsartan attenuates inflammation and myocardial fibrosis in Takotsubo-like cardiomyopathy.

Kuang J, Jia Z, Chong TK, Chen J, Liu K, Wang X, Li Z, Zhang J, Kong Y, Deng L, Cadieras M, Sun Y, Sun R, Lu Q, Liu Y
Journal of molecular and cellular cardiology 2025 Mar;200:24-39

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Development of Polyclonal Antibodies for the Preliminary Characterization of GPATCH1, a Novel Splicing Factor Associated with Human Osteoporosis.

Abudukeremu A, Azatibieke G, Yimiti G, Guan Y, Chen Z
Applied biochemistry and biotechnology 2025 Mar;197(3):1790-1804

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Oral exposure to nanoplastics altered lipid profiles in mouse intestine.

Luo S, Zhao X, Wang Y, Jiang M, Cao Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Mar;197:115304

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The role of GSK3β signaling mediated lysosomal biosynthesis dysregulation in fluoride-induced neurological impairment.

Cheng Y, Du Y, Hu Y, Wang X, Li Q, Yan X, Dou M, Jia W, Yu F, Ba Y, Zhou G
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Mar;197:115267

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Hypoxic stress promotes astrocyte infiltration-like growth via HIF-1α/GDNF/LOXL2 axis.

Li Z, Xi S, Zhang Z, Kan X, Zhang Y, Wang M, Wang Y, Shi Y, Xu H, Zhang B
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167702

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Synergistic anticancer activity of HSP70 and HSF1 inhibitors in colorectal cancer cells: A new strategy for combination therapy.

Xu SM, Liu XZ, Wang L, Huang WH, Hu YT, Chen SB, Huang ZS, Huang SL
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167630

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SIRT5 mediated succinylation of SUCLA2 regulates TCA cycle dysfunction and mitochondrial damage in pancreatic acinar cells in acute pancreatitis.

Liu W, Wang X, Xu D, Gong F, Pei L, Yang S, Zhao S, Zheng X, Li R, Yang Z, Fei J, Mao E, Chen E, Chen Y
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167613

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USP13 inhibition exacerbates mitochondrial dysfunction and acute kidney injury by acting on MCL-1.

Wang Q, Cao S, Sun Z, Zhu W, Sun L, Li Y, Luo D, Huang S, Zhang Y, Xia W, Zhang A, Jia Z
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167599

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Succinate dehydrogenase mediated ROS production contributes to ASIC1a-induced chondrocyte pyroptosis in rheumatoid arthritis.

Liu W, Xu Y, Hu W, Zhang L, Wang C, Wang F, Zai Z, Qian X, Peng X, Chen F
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167585

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Combined therapy with pirfenidone and nintedanib counteracts fibrotic silicosis in mice.

Bai L, Wang J, Wang X, Wang J, Zeng W, Pang J, Zhang T, Li S, Song M, Shi Y, Wang J, Wang C
British journal of pharmacology 2025 Mar;182(5):1143-1163

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Aerobic Exercise Affected Lymphocyte Apoptosis by Modulating ROS Release and NLRP3 Inflammasome Activation.

Lian X, Guo Z, Liu J, Zeng W
Bulletin of experimental biology and medicine 2025 Mar;178(5):685-690

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NSUN4 Facilitates the Activity of Oncogenic Protein CDC20 to Promote NSCLC Development by Mediating m5C Modification of CDC20 mRNA.

Li Z, Wu X
Thoracic cancer 2025 Mar;16(5):e70023

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Role of Xuefu Zhuyu decoction in improving pulmonary vascular remodeling by inhibiting endothelial-to-mesenchymal transition.

Zeng Z, Wang X, Wang H, Tian L, Cui L, Guo J, Chen Y
Vascular pharmacology 2025 Mar;158:107467

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Discovery of novel benzo[b][1,4]oxazine derivatives as ferroptosis inhibitors.

Wan BW, Liu W, Xiao Y, Lv L, Li X, Lin F, Zhao Y, He Y, Nie S, Yang X, Yuan HX
Bioorganic chemistry 2025 Mar;156:108201

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Targeting Zfp36 to combat cardiac hypertrophy: Insights into ferroptosis pathways.

Zhang M, Guan X, Dong Z, Yang C, Xiong C, Cheng W, Shang A, Liu Y, Guo X, Zhang B, Zhang B, Jin S, Qi W, Alexandrovna BT, Jiang Y, Du Z, Xu C
Clinical and translational medicine 2025 Mar;15(3):e70247

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2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione mediates the effect of ROS-enhanced PI3K/Akt/mTOR pathway on autophagy in breast cancer.

Chen L, Chen M, Xie Y, Zhang Y, Mo S, He Y, Liang T, Liao Y, Huang R, Huang G, Han C, Pham TTH
FEBS open bio 2025 Mar;15(3):474-489

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Elemene as a binding stabilizer of microRNA-145-5p suppresses the growth of non-small cell lung cancer.

Zhou M, Wang J, Peng Y, Tian X, Zhang W, Chen J, Wang Y, Wang Y, Yang Y, Zhang Y, Huo X, Wu Y, Yu Z, Xie T, Ma X
Journal of pharmaceutical analysis 2025 Mar;15(3):101118

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Integrated metabolomics and mass spectrometry imaging analysis reveal the efficacy and mechanism of Huangkui capsule on type 2 diabetic nephropathy.

Han J, Li P, Sun H, Zheng Y, Liu C, Chen X, Guan S, Yin F, Wang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Mar;138:156397

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Exploring the active components and potential mechanisms of Zhimu-Huangbai herb-pair in the treatment of depression.

Lei X, Zhao D, Chen T, Li Q, Xue A, Hu Z, Jia F, Li X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Mar;138:156365

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Oxaliplatin induces pyroptosis in hepatoma cells and enhances antitumor immunity against hepatocellular carcinoma.

Deng M, Zhao R, Zou H, Guan R, Wang J, Lee C, He B, Zhou J, Li S, Wei W, Cai H, Guo R
British journal of cancer 2025 Mar;132(4):371-383

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SEPT5 overexpression predicts poor prognosis and promotes progression through feedback regulation of HIF-1α in clear cell renal cell carcinoma.

Liu W, Ni Y, Wang W, Cui K, Duan Q, Bai Z, Shahzad A, Liu X, Dong Y, Xu Z, Zhang J, Peng D, Teng Z, Gao Y, Yang Z, Zhang Q
Cellular signalling 2025 Mar;127:111591

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USP27 promotes glycolysis and hepatocellular carcinoma progression by stabilizing PFKFB3 through deubiquitination.

Xie L, Song D, Ouyang Z, Ning Y, Liu X, Li L, Xia W, Yang Y
Cellular signalling 2025 Mar;127:111585

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METTL3-mediated m6A modifications of NLRP3 accelerate alveolar bone resorption through enhancing macrophage pyroptosis.

Yang Q, Xiao J, Liu Y, Yang Z, Wang C, Sun J, Wang H, Liu H, Wang X, Ma L, Huang X, Cao Z
Cellular signalling 2025 Mar;127:111572

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Extracellular vesicle-packaged PKM2 from endometriotic stromal cells promotes endometrial collagen I deposition by inhibiting autophagy in endometriosis.

Zhu Y, Gao L, Zhang J, Li M, Zhou J, Zhou J
Cellular signalling 2025 Mar;127:111523

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Microglia-Derived Interleukin-6 Triggers Astrocyte Apoptosis in the Hippocampus and Mediates Depression-Like Behavior.

Shen SY, Liang LF, Shi TL, Shen ZQ, Yin SY, Zhang JR, Li W, Mi WL, Wang YQ, Zhang YQ, Yu J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(11):e2412556

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Elevated SPARC Disrupts the Intestinal Barrier Integrity in Crohn's Disease by Interacting with OTUD4 and Activating the MYD88/NF-κB Pathway.

Wang J, He Y, Zhu X, Zhu J, Deng Z, Zhang H, Chen Y, Zhang G, Shi T, Chen W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(11):e2409419

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Exosome-Mediated Lectin Pathway and Resistin-MIF-AA Metabolism Axis Drive Immune Dysfunction in Immune Thrombocytopenia.

Li J, Wang X, Chen Y, Sun X, Fu L, Xin Q, Zhang H, Qin B, Sun N, Li Y, Xu Y, Yang H, Huo D, Dong Y, Wang S, Zhao M, Lin Q, Wang F, Yue B, Gao Y, Jiang Y, Guo R
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(10):e2412378

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Integrative analysis of genes provides insights into the molecular and immune characteristics of mitochondria-related genes in atherosclerosis.

Zheng Z, Lu H, Wang X, Yang Z, Zhang Y, Li K, Shen C, Yin Z, Sha M, Ye J, Zhu L
Genomics 2025 Mar;117(2):111013

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ARF3 as a novel biomarker and target in acute myeloid leukemia: Insights from pan-cancer analysis.

Wenli Y, Wei W, Yubiao P, Hua H, Hongyan T
Genomics 2025 Mar;117(2):110984

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Tumor exosomal RNPEP promotes lung metastasis of liver cancer via inducing cancer-associated fibroblast activation.

Chen Y, Pan G, Yang Y, Wu H, Weng M, Wu Q, Gao Y, Li W
Cancer science 2025 Mar;116(3):792-807

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The loss of both pUL16 and pUL21 in HSV-1-infected cells alters capsid-tegument composition, nuclear membrane architecture, cytoplasmic maturation and cell-to-cell spread.

Roddy K, Grzesik P, Smith BJ, Ko N, Vashee S, Desai PJ
The Journal of general virology 2025 Mar;106(3)

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Silencing long non-coding RNA linc00689 suppresses the growth and invasion of osteosarcoma cells by targeting miR-129-5p/NUSAP1.

Zhang L, Song J, Xu X, Sun D, Huang H, Chen Y, Zhang T
International journal of experimental pathology 2025 Mar;106(2):e12524

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Luteolin protects human ARPE-19 retinal pigment epithelium cells from blue light-induced phototoxicity through activation of Nrf2/Keap1 signaling.

Hayakawa R, Ishii T, Fushimi T, Kamei Y, Yamaguchi A, Sugimoto K, Ashida H, Akagawa M
Free radical research 2025 Mar-Apr;59(4):356-368

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Induction of UBQLN1-mediated PGC1α stability by isoliensinine overcame hypoxia-induced resistance in liver cancer cells.

Xu X, Li W, Zhou Y, Wang M, Ji S, Xia S, Li Y, Guo X, Huan S, Wang F, Zhang F, Cheng H, Yin G, Zheng S
BioFactors (Oxford, England) 2025 Mar-Apr;51(2):e70008

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Differential Expression of NRF2 in the Cortex and Hippocampus Following Bilateral Common Carotid Artery Occlusion.

Choi MS, Hwang HI, Chung YY, Shin HK, Kim DJ, Jun YH
In vivo (Athens, Greece) 2025 Mar-Apr;39(2):742-748

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TGEV nonstructural protein ORF3b upregulates the expression of SLA-DR at the transcriptional level in monocyte-derived porcine dendritic cells.

Liu H, Ma M, Jia X, Qian M, Pang B, Li M, Zhang H, Ma S, Zheng L
Microbes and infection 2025 Mar-Apr;27(3):105437

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NaHS@Cy5@MS@SP nanoparticles improve rheumatoid arthritis by inactivating the Hedgehog signaling pathway through sustained and targeted release of H(2)S into the synovium.

Zhu XX, Xu AJ, Cai WW, Han ZJ, Zhang SJ, Hou B, Wen YY, Cao XY, Li HD, Du YQ, Zhuang YY, Wang J, Hu XR, Bai XR, Su JB, Zhang AY, Lu QB, Gu Y, Qiu LY, Pan L, Sun HJ
Journal of nanobiotechnology 2025 Mar 8;23(1):192

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Depletion of MGO or Its Derivatives Ameliorate CUMS-Induced Neuroinflammation.

Liu B, Dong K, Zhao Y, Wang X, Sun Z, Xie F, Qian L
Cells 2025 Mar 8;14(6)

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Endogenous TDP-43 mislocalization in a novel knock-in mouse model reveals DNA repair impairment, inflammation, and neuronal senescence.

Mitra J, Kodavati M, Dharmalingam P, Guerrero EN, Rao KS, Garruto RM, Hegde ML
Acta neuropathologica communications 2025 Mar 8;13(1):54

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STAT1 mediates the pro-inflammatory role of GBP5 in colitis.

Li Y, Wang W, Zhu R, Zhu X, Sun M, Huang Y, Chen W, Gao S, Jiao N, Lin X, Ke J, Xu T, Hou L, Lan P, Zhu L
Communications biology 2025 Mar 7;8(1):385

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Clinical Response Characteristics of Salivary Proteins in the Management Strategy of Diabetes-Associated Periodontitis.

Jia S, Liang Q, Zhang Y, Diao J, Liu Y, Ye Y, Xu S, Yang W, Zhao Y, Ma B, Li X, Zheng S, Yuan C
Journal of proteome research 2025 Mar 7;24(3):1161-1179

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Citrulline regulates macrophage metabolism and inflammation to counter aging in mice.

Xie Z, Lin M, Xing B, Wang H, Zhang H, Cai Z, Mei X, Zhu ZJ
Science advances 2025 Mar 7;11(10):eads4957

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Mitochondrial priming and response to BH3 mimetics in "one-two punch" senogenic-senolytic strategies.

López J, Llop-Hernández À, Verdura S, Serrano-Hervás E, Martinez-Balibrea E, Bosch-Barrera J, Teixidor E, López-Bonet E, Martin-Castillo B, Sardanyés J, Alarcón T, Lupu R, Cuyàs E, Menendez JA
Cell death discovery 2025 Mar 7;11(1):91

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A missense mutation in PDHB gene: identification of the patient with pyruvate dehydrogenase deficiency and demonstration of pathogenicity in vitro.

Li Y, Cheng L, Li X, Liu J, Yi L, Bo T
Italian journal of pediatrics 2025 Mar 6;51(1):66

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The role and mechanism of CHMP4C in poor prognosis and drug sensitivity of lung adenocarcinoma.

Xu C, Liu M, Li Y, Peng X, Zhou W, Zhang W, Zhang J, Yu B
Discover oncology 2025 Mar 6;16(1):270

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Inhibiting HMGB1/AGER/NF-κB pathway prevents pro-inflammatory microglia polarization and protect photoreceptors in retinitis pigmentosa.

Hu C, Cui T, Xu Z, Yang K, Wu Y, Cai W, Yu J, Qiu Y
International immunopharmacology 2025 Mar 6;149:114192

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Cornuside as a promising therapeutic agent for diabetic kidney disease: Targeting regulation of Ca(2+) disorder-mediated renal tubular epithelial cells apoptosis.

Gao G, Su X, Liu S, Wang P, Chen JJ, Liu T, Xu J, Zhang Z, Zhang X, Xie Z
International immunopharmacology 2025 Mar 6;149:114190

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FTO/miR-503-5p/USP10 axis regulates neuronal endoplasmic reticulum stress-mediated apoptosis in ischemic stroke.

Peng Q, Wang S, Huang S, Deng Y, Li Z, Liu C, Hong Y, Duan R, Xue X, Ge P
International immunopharmacology 2025 Mar 6;149:114150

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Network pharmacology and molecular docking technology-based predictive study and potential targets analysis of icariin for the treatment of diabetic nephropathy.

Chen M, Zhou Y, Yang J, Yuan H
Biochemical and biophysical research communications 2025 Mar 5;751:151434

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Pathogenic germline variants in Chinese pancreatic adenocarcinoma patients.

Yin X, Shen H, Wang H, Wang Q, Zhang S, Zhang C, Jia Q, Guo S, Xu X, Zhang W, Li B, Shi X, Gao S, Shi M, Zhao X, Wang S, Han J, Zhang G, Li Y, Li P, Jing W, Song B, Zheng K, Li G, Zhang Y, Jiang H, Wu C, Song Z, Niu G, Zhang Q, Guo J, Sun Z, Han F, Li Y, Gao D, Jin H, Yang H, Li J, Jin G
Nature communications 2025 Mar 5;16(1):2214

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Gut dysbiosis conveys psychological stress to activate LRP5/β-catenin pathway promoting cancer stemness.

Cui B, Luo H, He B, Liu X, Lv D, Zhang X, Su K, Zheng S, Lu J, Wang C, Yang Y, Zhao Z, Liu X, Wang X, Zhao Y, Nie X, Jiang Y, Zhang Z, Liu C, Chen X, Cai A, Lv Z, Liu Z, An F, Zhang Y, Yan Q, Kelley KW, Xu G, Xu L, Liu Q, Peng F
Signal transduction and targeted therapy 2025 Mar 5;10(1):79

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Environmental Chemical-Induced Cardiometabolic Disorders: Combined Epidemiological and Experimental Evidence.

Jiang Q, Zhang D, Hu N, Ma Y, Jin H, Zhao Y, Zhang M, Li B, Huang Z, Yuan B, Zhu Y, Tian J, Miao X
Environmental science & technology 2025 Mar 4;59(8):3853-3868

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SRSF3 and hnRNP A1-mediated m6A-modified circCDK14 regulates intramuscular fat deposition by acting as miR-4492-z sponge.

Qin C, Xu F, Yue B, Zhong J, Chai Z, Wang H
Cellular & molecular biology letters 2025 Mar 4;30(1):26

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Photoinduced Actin Aggregation Involves Cell Death: A Mechanism of Cancer Cell Cytotoxicity after Near-Infrared Photoimmunotherapy.

Sato K, Okada T, Okada R, Yasui H, Yamada M, Isobe Y, Nishinaga Y, Shimizu M, Koike C, Fukushima R, Takahashi K, Taki S, Kato A, Sato M, Ogura T
ACS nano 2025 Mar 4;19(8):8338-8356

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NEAT1 promotes the perineural invasion of pancreatic cancer via the E2F1/GDNF axis.

Gu J, Wang Q, Mo J, Qin T, Qian W, Duan W, Han L, Wang Z, Ma Q, Ma J
Cancer letters 2025 Mar 31;613:217497

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TRIM21 promotes type I interferon by inhibiting the autophagic degradation of STING via p62/SQSTM1 ubiquitination in systemic lupus erythematosus.

Li C, Ma A, Bai Y, Liu Z, Tian L, Wang Z, Ma H, Chen Z, Gao Z, Feng S, Fu P
Acta biochimica et biophysica Sinica 2025 Mar 31;57(5):834-846

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ASFV pS183L protein negatively regulates RLR-mediated antiviral signalling by blocking MDA5 oligomerisation.

Chen H, Yu Q, Gao X, Huang T, Bao C, Guo J, Wang Z, Lv J, Dai J, Babiuk LA, Zou X, Jung YS, Qian Y
Veterinary research 2025 Mar 31;56(1):70

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Uric acid promotes aortic valve calcification via mediating valve interstitial cell osteogenic differentiation and endothelial dysfunction.

Zhang J, Lei W, Zhou J, Zhang Y, Huang F, Chen M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Mar 31;39(6):e70437

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Novel regulation mechanism of histone methyltransferase SMYD5 in rheumatoid arthritis.

Xiao C, Su Z, Zhao J, Tan S, He M, Li Y, Liu J, Xu J, Hu Y, Li Z, Fan C, Liu X
Cellular & molecular biology letters 2025 Mar 31;30(1):38

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ALDH1A3 Regulates Cellular Senescence and Senescence-Associated Secretome in Prostate Cancer.

Wang S, Wang L, Zhao Y
Cancers 2025 Mar 31;17(7)

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Scoparone suppresses proliferation and cell cycle of hepatocellular carcinoma cells via inhibiting AKT/GSK-3β/cyclin D1 signaling pathway.

Hong M, Zhu H, Liu W, Zhang P, Yu S, Gao Q, Shen G, Li B, Wang G
Translational cancer research 2025 Mar 30;14(3):1638-1650

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Butyrate Ameliorates Graves' Orbitopathy Through Regulating Orbital Fibroblast Phenotypes and Gut Microbiota.

Ouyang P, Qi J, Tong B, Li Y, Cao J, Wang L, Niu T, Qi X
Investigative ophthalmology & visual science 2025 Mar 3;66(3):5

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Unveiling the oncogenic role of SLC25A13: a multi-omics pan-cancer analysis reveals its impact on glioma progression.

Wu W, Liu S, Ren H, Rao Y, Nie J, Wei K, Jiang X
Cancer cell international 2025 Mar 3;25(1):76

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PTPN23-dependent activation of PI3KC2α is a therapeutic vulnerability of BRAF-mutant cancers.

He Y, Li W, Zhang M, Wang H, Lin P, Yu Y, Huang B, Hao M, He J, Kong W, Luo D, Xu T, Wang J, Huang Y, Zhao Q, Liu Y, Zhang J, Nian Y, Zhang L, Zhu B, Yin C
The Journal of experimental medicine 2025 Mar 3;222(3)

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FLT3 inhibition upregulates OCT4/NANOG to promote maintenance and TKI resistance of FLT3-ITD(+) acute myeloid leukemia.

Zhou Q, Li Z, Zhao P, Guan Y, Chu H, Xi Y
Oncogenesis 2025 Mar 29;14(1):7

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Condensates of synaptic vesicles and synapsin are molecular beacons for actin sequestering and polymerization.

Chhabra A, Hoffmann C, Pérez GA, Korobeinikov AA, Rentsch J, Hümpfer N, Kokwaro L, Gnidovec L, Petrovic A, Wallace JN, Tromm JV, Román-Vendrell C, Johnson EC, Ranković B, Perego E, Volpi T, Fernández-Busnadiego R, Köster S, Rizzoli SO, Ewers H, Morgan JR, Milovanovic D
bioRxiv : the preprint server for biology 2025 Mar 29;

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Ingenane Diterpenoids from Euphorbia peplus as Potential New CHK1 Inhibitors That Sensitize Cancer Cells to Chemotherapy.

Zhou M, Yang Y, He S, Xu Q, Du C, Tian W, Chen H
Journal of natural products 2025 Mar 28;88(3):688-705

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C-FOS promotes the formation of neutrophil extracellular traps and the recruitment of neutrophils in lung metastasis of triple-negative breast cancer.

Yan S, Zhao W, Du J, Teng L, Yu T, Xu P, Liu J, Yang R, Dong Y, Wang H, Lu L, Tao W
Journal of experimental & clinical cancer research : CR 2025 Mar 28;44(1):108

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The Marine Compound Isaridin E Ameliorates Lipopolysaccharide-Induced Vascular Endothelial Inflammation via the Downregulation of the TLR4/NF-κB Signaling Pathway.

Liu J, Zeng X, Lin YQ, Peng YS, Liu L, Chen SH, Du YH
Marine drugs 2025 Mar 28;23(4)

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The clinical antiprotozoal drug halofuginone promotes weight loss by elevating GDF15 and FGF21.

Xu S, Liu Z, Tian T, Zhao W, Wang Z, Liu M, Xu M, Zhang F, Zhang Z, Chen M, Yin Y, Su M, Fang W, Pan W, Liu S, Li MD, Little PJ, Kamato D, Zhang S, Wang D, Offermanns S, Speakman JR, Weng J
Science advances 2025 Mar 28;11(13):eadt3142

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WWC1 mutation drives dopamine dysregulation and synaptic imbalance in Tourette's syndrome.

Lv J, Liang S, Qin P, Liu X, Ge X, Guo Y, Xia S, Jing W, Lu Y, Zhang T, Li H
Science advances 2025 Mar 28;11(13):eadr4588

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Electroacupuncture reduces microglial pyroptosis via P2X7R/NLRP3 axis in the rat model of asphyxial cardiac arrest and cardiopulmonary resuscitation.

Yan YT, Guo F, Liu YF, Zhao ZY, Sun XD, Gao CJ
Neuroscience 2025 Mar 27;570:27-37

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Systematically investigate the mechanism underlying the therapeutic effect of emodin in treatment of prostate cancer.

Yuan G, Mao J, Li Z
Discover oncology 2025 Mar 27;16(1):413

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Single-cell analysis reveals that GFAP(+) dedifferentiated Schwann cells promote tumor progress in PNI-positive distal cholangiocarcinoma via lactate/HMGB1 axis.

Zu Z, Zhang C, Shi J, Chen K, Tang H, Hu K, Liu E, Ji C, Feng R, Shi X, Zhai W
Cell death & disease 2025 Mar 27;16(1):215

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Proteomic Sensors for Quantitative, Multiplexed and Spatial Monitoring of Kinase Signaling.

Smolka M, Comstock W, Navarro M, Maybee D, Rho Y, Wagner M, Wang Y
Research square 2025 Mar 27;

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The anti-inflammatory effects of paeonol from Cynanchum paniculatum extracts on LPS-induced macrophage RAW 264.7 cells and Helicobacter pylori-infected gastrointestinal mucosal damaged zebrafish.

Wang M, Zhou J, Li L, Zhang T, Pu Y
Journal of ethnopharmacology 2025 Mar 26;344:119530

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The Effect of G0S2 Gene Knockout on the Proliferation, Apoptosis, and Differentiation of Chicken Preadipocytes.

Li Y, Wang B, Wang Z, Wen J, Zhou T, Tang J, Li Z
Animals : an open access journal from MDPI 2025 Mar 26;15(7)

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Multicilia dynamically transduce Sonic Hedgehog signaling to regulate choroid plexus functions.

Mao S, Song R, Jin S, Pang S, Jovanovic A, Zimmerman A, Li P, Wu X, Wendland MF, Lin K, Chen WC, Choksi SP, Chen G, Holtzman MJ, Reiter JF, Wan Y, Xuan Z, Xiang YK, Xu CS, Upadhyayula S, Hess HF, He L
Cell reports 2025 Mar 25;44(3):115383

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DKS26 Alleviates Ischemia-Reperfusion Injury-Induced Acute Kidney Injury by Stabilizing Vitamin D Receptors to Inhibit the Inflammatory Pathway of NF-κB P65.

Liang L, Ruan Y, Yu X, Tan W, Xu X, Jia J, Peng J, Wang F, Peng Y, Chen Y, Liu L, Guo B, Zhang J, Wang Y
International journal of molecular sciences 2025 Mar 25;26(7)

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FVB But Not B6 Mice Carrying the Thr92Ala-Dio2 Polymorphism Have Impaired Thyroid Hormonogenesis and Goiter.

Batistuzzo A, Zhang X, Bocco BMLC, McAninch EA, Salas-Lucia F, Ribeiro MO, Arvan P, Bianco AC, Fonseca TL
Endocrinology 2025 Mar 24;166(5)

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Dietary emulsifier carboxymethylcellulose-induced gut dysbiosis and SCFA reduction aggravate acute pancreatitis through classical monocyte activation.

Feng Y, Chen W, Chen J, Sun F, Kong F, Li L, Zhao Y, Wu S, Li Z, Du Y, Kong X
Microbiome 2025 Mar 24;13(1):83

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CDX1 improves nicotine induced cardiac fibroblasts activation and cardiomyocyte hypertrophy by alleviating autophagic flux impairment through modulation of LAPTM4B.

Li YY, Meng FL, Zhou SY, Du JM, Li WJ, Liu QY, Wu L, Zhao MM, Jin Y, Zhang QY, Li Y, Su GH
Scientific reports 2025 Mar 22;15(1):9985

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Identification of RNA processing factor LSM5 as a new adverse biomarker in nasopharyngeal carcinoma.

Lin T, Deng L, Liu S, Chen Y, Tang Y, Zhou F, Gong G, He Y
Scientific reports 2025 Mar 22;15(1):9901

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Gastrodia elata, Polygonatum sibiricum, and Poria cocos as a Functional Food Formula: Cognitive Enhancement via Modulation of Hippocampal Neuroinflammation and Neuroprotection in Sleep-Restricted Mice.

Zhang Y, Chen F, Li X, Xu Y, Liu X, Barkat MQ, Choudhary MI, Chang Q, Jiang N
Foods (Basel, Switzerland) 2025 Mar 22;14(7)

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tRF-Val-TAC-004 protects against renal ischemia-reperfusion injury via attenuating Apaf1-mediated apoptosis.

Yin N, Xie X, Li D, Yang S, Liu Y, Tang Y, Zhang H, Zhang W
iScience 2025 Mar 21;28(3):111954

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PLGA-Encapsulated Elvitegravir and Curcumin Modulates ART Penetration, Oxidative Stress, and Inflammation.

Godse S, Zhou L, Sinha N, Mirzahosseini G, Kumar S
Brain sciences 2025 Mar 21;15(4)

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Protocol Development for CRISPR/Cas9 Knockout of the Anti-inflammatory Protein TNIP1 in HaCaT Keratinocytes.

Carman LE, Samulevich ML, Aneskievich BJ
Methods in molecular biology (Clifton, N.J.) 2025 Mar 20;

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Epigallocatechin Gallate Alleviates Lipopolysaccharide-Induced Intestinal Inflammation in Wenchang Chicken by Inhibiting the TLR4/MyD88/NF-κB Signaling Pathway.

Xu X, Li K, Liu Q, Zhang H, Li L
Veterinary sciences 2025 Mar 2;12(3)

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Selenium deficiency exacerbates cartilage degradation caused by HT-2 toxin via notch signaling pathway activation.

Meng P, Liu L, Jiang N, Hao S, Yao C, Liu H, Zhang Y, Zhang F, Jia Y, Guo X
European journal of nutrition 2025 Mar 19;64(3):129

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Leukemia Inhibitory Factor Attenuates Hypoxic-Ischemic White Matter Injury via NLRP3 Inflammasome Activity Suppressing Through the Nrf2/HO-1 Pathway.

Huo L, Liu X, Wang H
Frontiers in bioscience (Landmark edition) 2025 Mar 19;30(3):36630

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Fc fragment of IgG binding protein suppresses tumor growth by stabilizing wild type P53 in colorectal cancer cells.

Wang J, Gong Z, Liu J, Wang W, Liu K, Yang Y, Lu X, Wang J
BMC cancer 2025 Mar 19;25(1):507

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CHI3L1: a key driver in gastritis-to-cancer transformation.

Li T, Jiang H, Gong Y, Liao M, Jia Y, Chen J, Dai M, Yan Y, Lu X, Chen R, Li Y, Chen Y, Lin J, Li Y, Ding X
Journal of translational medicine 2025 Mar 19;23(1):349

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Targeting host integrated stress response: lead discovery of flavonoid compounds active against coronaviruses PEDV and PDCoV.

Yi L, Wang Y, Wang J, Chen Y, Huang W, Liao Y, Zhang Q
RSC medicinal chemistry 2025 Mar 19;16(3):1131-1140

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Septin5 deletion enhances β-cell exocytosis by releasing microtubule-tethered insulin granules onto plasma membrane.

Xie L, Kang F, Qin T, Kang Y, Liang T, Xie H, Froese CD, Xie H, Au A, Yip CM, Trimble WS, Gaisano HY
Nature communications 2025 Mar 19;16(1):2725

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POLM inhibits porcine epidemic diarrhea virus replication by degrading multiple viral structural proteins.

Cao X, Liu Y, Tong W, Qin W, Yang X, Yu H, Zheng H, Zhang W, Tong G, Kong N, Shan T
Journal of virology 2025 Mar 18;99(3):e0227824

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Seneca Valley virus 3C protease cleaves HDAC4 to antagonize type I interferon signaling.

Li Z, Yang J, Ma R, Xie S, Wang D, Quan R, Wen X, Liu J, Song J
Journal of virology 2025 Mar 18;99(3):e0217624

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STT3B promotes porcine epidemic diarrhea virus replication by regulating N-glycosylation of PEDV S protein.

Zhu H, Lou J, Yang Z, Bai J, Jiang P, Wang X, Liu X
Journal of virology 2025 Mar 18;99(3):e0001825

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CD4(+) anti-TGF-β CAR T cells and CD8(+) conventional CAR T cells exhibit synergistic antitumor effects.

Zheng D, Qin L, Lv J, Che M, He B, Zheng Y, Lin S, Qi Y, Li M, Tang Z, Wang BC, Wu YL, Weinkove R, Carson G, Yao Y, Wong N, Lau J, Thiery JP, Qin D, Pan B, Xu K, Zhang Z, Li P
Cell reports. Medicine 2025 Mar 18;6(3):102020

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Shengui Sansheng San alleviates the worsening of blood-brain barrier integrity resulted from delayed tPA administration through VIP/VIPR1 pathway.

Hu J, Li Y, Quan X, Han Y, Chen J, Yuan M, Chen Y, Zhou M, Yu E, Zhou J, Wang D, Wang R, Zhao Y
Chinese medicine 2025 Mar 18;20(1):38

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Deep Learning Enhanced Near Infrared-II Imaging and Image-Guided Small Interfering Ribonucleic Acid Therapy of Ischemic Stroke.

Yu K, Fu L, Chao Y, Zeng X, Zhang Y, Chen Y, Gao J, Lu B, Zhu H, Gu L, Xiong X, Hu Z, Hong X, Xiao Y
ACS nano 2025 Mar 18;19(10):10323-10336

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Assembling Ruthenium Complexes to Form Ruthenosome Unleashing Ferritinophagy-Mediated Tumor Suppression.

Meng C, Li S, Ma Y, Yu H, Song J, Zhi J, Zhu B, Shao L, Liu X, Yang L, Zhang M, Zhang Y, Li G
ACS nano 2025 Mar 18;19(10):10207-10219

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Mechanism of action for Troxerutin targeting the sialylation-related gene EGLN3 for the treatment of LUAD.

Wu Y, Ge Y, Gan J, Jin Y, Cui Y, Zheng X, Yao X, Sun G
Scientific reports 2025 Mar 18;15(1):9298

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Heat-killed Lacticaseibacillus paracasei 6235 is more effective than live on DSS-induced colitis via modulation of intestinal microbiota and MAPK/NF-κB signaling pathways.

Wang Y, Xie Z, Du L, Wang Q, Zhang L, Wu Y, Han J
Food & function 2025 Mar 17;16(6):2247-2261

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Ubiquitination of gasdermin D N-terminal domain directs its membrane translocation and pore formation during pyroptosis.

Chu X, Zhang T, Bukhari I, Hu M, Xu J, Xing Y, Liang X, Zhang Z, Zheng P
Cell death & disease 2025 Mar 17;16(1):181

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Therapeutic targeting de novo purine biosynthesis driven by β-catenin-dependent PPAT upregulation in hepatoblastoma.

Ding M, Ma C, Lin Y, Fang H, Xu Y, Wang S, Chen Y, Zhou J, Gao H, Shan Y, Yang L, Sun H, Tang Y, Wu X, Zhu L, Zheng L, Assaraf YG, Zhou BS, Gu S, Li H
Cell death & disease 2025 Mar 17;16(1):179

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Organelle-tuning condition robustly fabricates energetic mitochondria for cartilage regeneration.

Chen X, Zhou Y, Yao W, Gao C, Sha Z, Yi J, Wang J, Liu X, Dai C, Zhang Y, Wu Z, Yao X, Zhou J, Liu H, Chen Y, Ouyang H
Bone research 2025 Mar 17;13(1):37

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Plasma-activated saline hyperthermic perfusion-induced pyroptosis boosts peritoneal carcinomatosis immunotherapy.

Qi M, Zhao X, Fan R, Lin J, Li Z, Liu N, Sun X, Xu D, Zheng J, Liu D, Zhou R, Rong M, Ostrikov KK
Free radical biology & medicine 2025 Mar 16;230:177-189

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S100A8 induces cyclophosphamide-induced alopecia via NCF2/NOX2-mediated ferroptosis.

Xu W, Li Y, Wan S, Zhang B, Wei D, Zhang H, Jin X, Xie B, Guan C, Song X
Free radical biology & medicine 2025 Mar 16;230:112-126

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Neuroprotective effect of apo-9'-fucoxanthinone against cerebral ischemia injury by targeting the PI3K/AKT/GSK-3β pathway.

Qi Y, Tang S, Jin S, Wang J, Zhang Y, Xu X, Zhu H, Zhang J, Xu X, Zhao M, Zhu H, Yan P
European journal of pharmacology 2025 Mar 15;991:177348

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Exploring the effect of chlorogenic acid on oxidative stress and autophagy in dry eye mice via the AMPK/ULK1 pathway.

Chen H, Shi J, Tang Y, Chen X, Wang Z, Liu Q, Wu K, Yao X
European journal of pharmacology 2025 Mar 15;991:177311

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Sulfur dioxide increases testosterone biosynthesis by activating ERK1/2 pathway and disrupting autophagy in Leydig cells.

Li X, Shi Y, Liu S, Feng Z, Xiao H, Li R, Li Z, Zhang X, Han Y, Wang J, Liang C, Bai J, Zhang J
Journal of hazardous materials 2025 Mar 15;486:137001

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Threonine and tyrosine kinase promotes multiple myeloma progression by regulating regucalcin expression.

Zhu X, Feng Z, Peng X, Di T, Li Y, Bai J, Ma T, Li L, Zhang L
Experimental cell research 2025 Mar 15;446(2):114454

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Integrative multi-omics reveals the mechanism of ulcerative colitis treated with Ma-Mu-Ran antidiarrheal capsules.

Huang H, Duan B, Huang Z, Wang S, Wen Y, Jiang Q, Chen P, Huang P, Liu J, Zheng S, Ye Y, Zhang D, Wang Q, Huang F, Li J, Han L
Rapid communications in mass spectrometry : RCM 2025 Mar 15;39(5):e9939

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Oxidative stress regulates the catalytic activity and mitochondrial localization of HK2 in trophoblast by regulating K346 lactylation.

Chen Z, Wan L, Wu M, Zhao Y, Huang H, He Q, Wang Y, Luo Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Mar 15;39(5):e70429

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Hippocampus carbonic anhydrase 1 via ERK pathway may be involved in depressive like behaviors.

Cheng K, Chen C, Deng S, Xu F, Chen X, Yang J, Wang G, Xie P
Journal of affective disorders 2025 Mar 15;373:186-195

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Self-assembled injectable Icariin@ Ti(3)C(2)Tx/doxorubicin hydrogel preserving osteogenesis while synergizing photodynamic and chemodynamic therapy for osteosarcoma.

Fu J, Chen H, Zhao Y, Xi H, Huang Y, Liu C, Wu Y, Song W, Liu X, Du B, Sun G
Journal of materials science. Materials in medicine 2025 Mar 15;36(1):28

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Integration analysis of miRNA-mRNA uncovers the mechanisms of ochratoxin A-induced hepatotoxicity.

Luo Z, Jin R, Pan F, Guo R, Li M, Zhang S, Shi J, Zheng J, Wang H, Yang X, Yang J, Yu G
Ecotoxicology and environmental safety 2025 Mar 15;293:118039

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NNMT promotes acquired EGFR-TKI resistance by forming EGR1 and lactate-mediated double positive feedback loops in non-small cell lung cancer.

Dai J, Lu X, Zhang C, Qu T, Li W, Su J, Guo R, Yin D, Wu P, Han L, Zhang E
Molecular cancer 2025 Mar 15;24(1):79

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Functional nanozyme system for synergistic tumor immunotherapy via cuproptosis and ferroptosis activation.

Gu L, Sun Y, Bai T, Shao S, Tang S, Xue P, Cai W, Qin X, Zeng X, Yan S
Journal of nanobiotechnology 2025 Mar 15;23(1):212

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IFN-γ signaling links ventriculomegaly to choroid plexus and ependyma dysfunction following maternal immune activation.

Sun YQ, Huang XX, Guo W, Hong C, Ji J, Zhang XY, Yang J, Hu G, Sun XL
Journal of neuroinflammation 2025 Mar 15;22(1):83

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Engineered macrophage membrane-coated nanoparticles attenuate calcium oxalate nephrocalcinosis-induced kidney injury by reducing oxidative stress and pyroptosis.

Ba X, Ye T, He Y, Tong Y, Shang H, Wu J, Deng W, Zhong Z, Yang X, Wang K, Xie Y, Jiang K, Guo X, Tang K
Acta biomaterialia 2025 Mar 15;195:479-495

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To investigate the effect and mechanism of tetrahydrocurcumin on hepatocellular carcinoma based on phosphoinositide 3-kinases/AKT signaling pathway.

Bao ZC, Liu ZD, Zhang Y, Dai HJ, Jia H, Ren F, Li N, Zhao L, Wang YW, Lv SY, Zhang Y
World journal of gastrointestinal oncology 2025 Mar 15;17(3):102187

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N6-methyladenosine methyltransferase Wilms tumor 1-associated protein impedes diabetic wound healing through epigenetically activating DNA methyltransferase 1.

Xiao RJ, Wang TJ, Wu DY, Yang SF, Gao H, Gan PD, Yi YY, Zhang YL
World journal of diabetes 2025 Mar 15;16(3):102126

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Lysophosphatidylcholine promoting α-Synuclein aggregation in Parkinson's disease: disrupting GCase glycosylation and lysosomal α-Synuclein degradation.

Mu C, Shao K, Su M, Guo Y, Qiu Y, Sun R, Sun S, Sun Y, Liu C, Wang W, Qin X, Tang C
NPJ Parkinson's disease 2025 Mar 15;11(1):47

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Ciliary neurotrophic factor (CNTF) contributes to pelvic organ prolapse by modulating collagen expression via the JAK2-STAT3 pathway.

Xu Z, Zhu Q, Yang Y, Shan W, Jiang F, Zou Q, Wang W
Journal of molecular histology 2025 Mar 14;56(2):107

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Viral expression of NE/PPE enhances anti-colorectal cancer efficacy of oncolytic adenovirus by promoting TAM M1 polarization to reverse insufficient effector memory/effector CD8(+) T cell infiltration.

Wang S, Kong L, Wang L, Zhuang Y, Guo C, Zhang Y, Cui H, Gu X, Wu J, Jiang C
Journal of experimental & clinical cancer research : CR 2025 Mar 14;44(1):97

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miR-138-5p inhibits healing of femoral fracture osteogenesis in rats by modulating osteoblast differentiation via SIRT1/FOXO1 axis.

Dai G, Jiang W, Feng B, Zhang L
Journal of orthopaedic surgery and research 2025 Mar 14;20(1):280

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The critical role of the ZBP1-NINJ1 axis and IRF1/IRF9 in ethanol-induced cell death, PANoptosis, and alcohol-associated liver disease.

Qin Q, Chen W, King CD, Kumar SP, Vogel P, Tweedell RE, Kanneganti TD
bioRxiv : the preprint server for biology 2025 Mar 14;

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Discovery of Novel Oxazolo[4,3-f]purine Derivatives as Antitumor Agents through PPIA Interaction.

Li XJ, Zhang MC, Li X, Guan LL, Liang YR, Hao EJ, Wang Y, Guo HM
Journal of medicinal chemistry 2025 Mar 13;68(5):5573-5596

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Modulating HIF-1α/HIF-2α homeostasis with Shen-Qi-Huo-Xue formula alleviates tubular ferroptosis and epithelial-mesenchymal transition in diabetic kidney disease.

Yang R, Liu W, Zhou Y, Cheng B, Liu S, Wu R, Liu Y, Li J
Journal of ethnopharmacology 2025 Mar 13;343:119478

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Target inhibition of SPAK in choroid plexus attenuates T cell infiltration and demyelination in experimental autoimmune encephalomyelitis.

Qi C, Wang Y, Li X, Zheng C, Gu Y, Hu J, Qiu Y, Xie G, Xu S, Zheng Y, Lv Z, Zheng W
Journal of neuroinflammation 2025 Mar 13;22(1):80

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Administration of Porphyromonas gingivalis in pregnant mice enhances glycolysis and histone lactylation/ADAM17 leading to cleft palate in offspring.

Zhao X, Zheng X, Wang Y, Chen J, Wang X, Peng X, Yuan D, Liu Y, Wang Z, Du J
International journal of oral science 2025 Mar 13;17(1):18

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Identification of a non-inhibitory aptameric ligand to CRL2(ZYG11B) E3 ligase for targeted protein degradation.

Yang Z, Chen M, Ge R, Zhou P, Pan W, Song J, Ma S, Chen S, Xu C, Zhou M, Mi W, Ni H, Chen H, Yao X, Dong X, Chen Y, Zhou J, Xuan C, Dong C, Yan H, Xie S
Nature communications 2025 Mar 13;16(1):2494

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Proteomic Sensors for Quantitative, Multiplexed and Spatial Monitoring of Kinase Signaling.

Comstock WJ, Navarro MV, Maybee DV, Rho Y, Wagner M, Wang Y, Smolka MB
bioRxiv : the preprint server for biology 2025 Mar 13;

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Microenvironmental arginine restriction sensitizes pancreatic cancers to polyunsaturated fatty acids by suppression of lipid synthesis.

Jonker PB, Sadullozoda M, Cognet G, Saab JJA, Sokol KH, Wu VX, Kumari D, Sheehan C, Ozgurses ME, Agovino D, Croley G, Patel SA, Bock-Hughes A, Macleod KF, Shah H, Coloff JL, Lien EC, Muir A
bioRxiv : the preprint server for biology 2025 Mar 13;

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Exosomes containing miR-152-3p targeting FGFR3 mediate SLC7A7-induced angiogenesis in bladder cancer.

Cao C, Wang Y, Deng X, Zhao X, Chen Y, Tan W, Deng F, Li F
NPJ precision oncology 2025 Mar 12;9(1):71

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PKM2 knockout facilitates the activation of the AMPK/KLF4/ACADVL pathway, leading to increased oxidative degradation of fatty acids in TNBC.

Zhang L, Cheng L, Ma Y, Li J, Zhong Y, Zhu X, Leng X, Xie F
Medical oncology (Northwood, London, England) 2025 Mar 12;42(4):102

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Injectable hydrogels with ROS-triggered drug release enable the co-delivery of antibacterial agent and anti-inflammatory nanoparticle for periodontitis treatment.

Zhu Y, Xiu Z, Jiang X, Zhang H, Li X, Feng Y, Li B, Cai R, Li C, Tao G
Journal of nanobiotechnology 2025 Mar 12;23(1):205

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Puerarin Targets HIF-1α to Modulate Hypoxia-Related Sphingolipid Metabolism in Diabetic Hepatopathy via the SPTLC2/Ceramide Pathway.

Cai M, Lai W, Chen H, Cao D, Zhang B, Wang F, Xian M, Wang S
Pharmaceuticals (Basel, Switzerland) 2025 Mar 12;18(3)

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SARM regulates cell apoptosis and inflammation during Toxoplasma gondii infection through a multistep mechanism.

Gao S, Gao M, Du H, Li L, An X, Shi Y, Wang X, Cong H, Han B, Zhou C, Zhou H
Parasites & vectors 2025 Mar 12;18(1):103

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An investigation into the mechanism for Kaempferol improving melanocyte death based on network Pharmacology and experimental verification.

Li J, Song Y, Yang M
Scientific reports 2025 Mar 12;15(1):8616

---

Identification and verification of biomarkers associated with arachidonic acid metabolism in non-alcoholic fatty liver disease.

Li J, Su WW, Wang ZL, Ji XF, Wang JW, Wang K
Scientific reports 2025 Mar 12;15(1):8521

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Starvation-induced HBP metabolic reprogramming and STAM2 O-GlcNAcylation facilitate bladder cancer metastasis.

Feng Z, Mei Y, Chen H, Li L, Jin T, Li X, Gou X, Chen Y
Scientific reports 2025 Mar 12;15(1):8480

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Engineered circular RNA-based DLL3-targeted CAR-T therapy for small cell lung cancer.

Cai J, Liu Z, Chen S, Zhang J, Li H, Wang X, Yang F, Wang S, Li X, Li Y, Chen K, Wang J, Sun M, Qiu M
Experimental hematology & oncology 2025 Mar 12;14(1):35

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Influenza virus antagonizes self sensing by RIG-I to enhance viral replication.

Ledwith MP, Nipper T, Davis KA, Uresin D, Komarova AV, Mehle A
bioRxiv : the preprint server for biology 2025 Mar 12;

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Necrosis drives susceptibility to Mycobacterium tuberculosis in Polg(D257A) mutator mice.

Mabry CJ, Weindel CG, Stranahan LW, VanPortfliet JJ, Davis JR, Martinez EL, West AP, Patrick KL, Watson RO
Infection and immunity 2025 Mar 11;93(3):e0032424

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Sex-specific attenuation of constant light-induced memory impairment and Clock gene expression in brain in hepatic Npas2 knockout mice.

Chrisp R, Masterson M, Pope R, Roberts CJ, Collins HM, Watson DJG, O'Neil D, Aagaard KM, Gibson CL, Heery DM, Moran PM
Scientific reports 2025 Mar 11;15(1):8347

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Chaetocin, a Natural Inhibitor of Transketolase, Suppresses the Non-Oxidative Pentose Phosphate Pathway and Inhibits the Growth of Drug-Resistant Non-Small Cell Lung Cancer.

Li S, Lu Z, Jiang W, Xu Y, Chen R, Wang J, Jiao B, Lu X
Antioxidants (Basel, Switzerland) 2025 Mar 11;14(3)

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Dual-responsive stem cell microspheres modified with BDNF for enhanced neural repair in diabetic erectile dysfunction.

Pan X, Xing X, Ji Z, Zhang J, Chen Q, Yin W, Zang Y, Yang Y, Liu Z, Xu Y
Journal of controlled release : official journal of the Controlled Release Society 2025 Mar 10;379:409-420

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The asymmetric expression of HSPA2 in blastomeres governs the first embryonic cell-fate decision.

Gao J, Wang J, Liu S, Song J, Zhang C, Liu B, Wu K
eLife 2025 Mar 10;13

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A novel KEAP1 inhibitor, tiliroside, activates NRF2 to protect against acetaminophen-induced oxidative stress and acute liver injury.

Cai F, Zhou K, Wang P, Zhang W, Liu L, Yang Y
Hepatology communications 2025 Mar 1;9(3)

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Activation of megakaryocytic leukemia 1 in endothelial cells contributes to diabetic retinopathy in mice.

Zhu Y, Feng X, Wang F, Ding Y
Life sciences 2025 Mar 1;364:123425

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GRASP55 regulates sorting and maturation of the lysosomal enzyme β-hexosaminidase A.

Akaaboune SR, Javed A, Bui S, Wierenga A, Wang Y
Molecular biology of the cell 2025 Mar 1;36(3):ar30

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Tasquinimod promotes the sensitivity of ovarian cancer cells to cisplatin by down-regulating the HDAC4/p21 pathway.

Li Z, Wu YH, Guo YQ, Min XJ, Lin Y
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2025 Mar 1;29(2):191-204

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MnSOD non-acetylation mimic knock-in mice exhibit dilated cardiomyopathy.

Schell JR, Wei SJ, Zhang J, Trevino R Jr, Chen WH, Aguilar L, Qian W, Corbett CW, Jiang H, Dong FF, Chocron ES, Nazarullah A, Chang J, Flanagan ME, Glatt V, Dikalov S, Munkácsy E, Horikoshi N, Gius D
Free radical biology & medicine 2025 Mar 1;229:58-67

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Naotaifang formula regulates Drp1-induced remodeling of mitochondrial dynamics following cerebral ischemia-reperfusion injury.

She R, Tian H, Sun F, Ge J, Mei Z
Free radical biology & medicine 2025 Mar 1;229:139-153

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Microenvironment-induced programmable nanotherapeutics restore mitochondrial dysfunction for the amelioration of non-alcoholic fatty liver disease.

Zhang J, Yang W, Zhu Y, Li Z, Zheng Y, Zhang Y, Gao W, Zhang X, Wu Z, Gao L
Acta biomaterialia 2025 Mar 1;194:323-335

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LCN2 induces neuronal loss and facilitates sepsis-associated cognitive impairments.

Guo C, Li W, Liu Y, Mahaman Yacoubou AR, Wang J, Liu R, Li S, Wang X
Cell death & disease 2025 Mar 1;16(1):146

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PFKM-Mediated Glycolysis: A Pathway for ASIC1 to Enhance Cell Survival in the Acidic Microenvironment of Liver Cancer.

Wu X, Wang B, Hou Y, Fang Y, Jiang Y, Song Y, Liu Y, Jin C
Biomolecules 2025 Mar 1;15(3)

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Bmi-1 alleviates alveolar bone resorption through the regulation of autophagy.

Chu Y, Liu S, Yan L, Gong A
Journal of periodontology 2025 Jun;96(6):694-707

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The safety assessment of cinnabar: Effects of co-administration with selenium on renal toxicity in mice.

Han Z, Zhuo Y, Dai Z, Zhang X, Zhu B, Liu Y, Chai Z, Wu J, Chen L
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2025 Jun;89:127671

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Ginsenoside Rb1 combined with Lycium barbarum polysaccharide alleviate the Tripterygium wilfordii polyglycoside-induced oligoasthenozoospermia in mice by inhibiting ZnT3-mediated oxidative stress response.

Li X, Ding J, Wang J, He J, Sheng W
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2025 Jun;89:127646

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Sirt4 Overexpression Modulates the JAK2/STAT3 and PI3K/AKT/mTOR Axes to Alleviate Sepsis-Induced Acute Lung Injury.

Xie C, Wang T, Liu A, Huang B, Zeng W, Li Z, Peng S, Wu S
Cell biochemistry and biophysics 2025 Jun;83(2):1785-1798

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Protein S-glutathionylation confers cellular resistance to ferroptosis induced by glutathione depletion.

Ju Y, Zhang Y, Tian X, Zhu N, Zheng Y, Qiao Y, Yang T, Niu B, Li X, Yu L, Liu Z, Wu Y, Zhi Y, Dong Y, Xu Q, Yang X, Wang X, Wang X, Deng H, Mao Y, Li X
Redox biology 2025 Jun;83:103660

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New mechanism of miR-34a-5p in regulating the biological behavior of osteosarcoma by targeting FoxM1.

Shen W, Liu X, Wang S, Du S, Cong L, Ma Y, Ye K
Cytotechnology 2025 Jun;77(3):90

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Ginsenoside Rh4 inhibits colorectal cancer via the modulation of gut microbiota-mediated bile acid metabolism.

Bai X, Duan Z, Deng J, Zhang Z, Fu R, Zhu C, Fan D
Journal of advanced research 2025 Jun;72:37-52

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Targeting MAD2B as a strategy for ischemic stroke therapy.

Zhang L, Cui H, Hu W, Meng X, Zhang C
Journal of advanced research 2025 Jun;72:369-385

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TREML2 enhances sensitivity of acute myeloid leukemia cells to chemotherapy by inhibiting the NF-κB/CXCL10 pathway.

Zhang X, Yan S, Zhang X, Huang D, Zhou J, Song X, Hao Y, Wang X, Yan J
Blood science (Baltimore, Md.) 2025 Jun;7(2):e00223

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Milk Exosomes From Gestational Diabetes Mellitus Parturients Demonstrate Weaker Ability to Promote Intestinal Development in Offspring.

Mo J, Ding Y, Yang J, Zheng Z, Lu J, Luo H, Wang J, Lin F, Chen J, Li Q, Zheng X, Zha L
Molecular nutrition & food research 2025 Jun;69(11):e70026

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Natural resistance to cancers in long-lived mammals: genomic mechanisms and experimental evidence to explain Peto's paradox.

Sun L, Xu Z, Shuai M, Li C, Yang G, Xu S
Science China. Life sciences 2025 Jun;68(6):1801-1814

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Piezo1 promotes double-directional differentiation from human periodontal ligament progenitor cells.

Kono Y, Kajiya H, Nagano R, Tominaga C, Maeda H, Fujita T, Tamaoki S
Journal of oral biosciences 2025 Jun;67(2):100651

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A battery-free nanofluidic intracellular delivery patch for internal organs.

Yin D, Wang P, Hao Y, Yue W, Jiang X, Yao K, Wang Y, Hang X, Xiao A, Zhou J, Lin L, Rao Z, Wu H, Liu F, Dong Z, Wu M, Xu C, Huang J, Chang H, Fan Y, Yu X, Yu C, Chang L, Li M
Nature 2025 Jun;642(8069):1051-1061

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LINC02154 Promotes Esophageal Squamous Cell Carcinoma Progression via the PI3K-AKT-mTOR Signaling Pathway by Interacting With IGF2BP2.

Zhang M, Zhang C, Zhou F, Yang R, Feng Y, Ji Y, Ren H, Ming L
Molecular carcinogenesis 2025 Jun;64(6):985-996

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miR-758-3p Interferes with Neuronal Apoptosis in Cerebral Ischemia-Reperfusion by Inhibiting ILK.

Min X, Bai X, Zhao Q, Yang W, Lin S, Xian L, Jing R, Li X, Jia W, Miao W, Yin M, Shang F, Zeng Y
Molecular neurobiology 2025 Jun;62(6):7805-7819

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Functional characteristics of equilibrative nucleoside transporter 2 (ENT2/SLC29A2) for the transport of urate as a newly identified substrate.

Matake I, Yasujima T, Matsuo H, Toyoda Y, Kawamura Y, Takada T, Inoue K, Yamashiro T, Yuasa H
Drug metabolism and pharmacokinetics 2025 Jun;62:101048

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Deuterium-depleted water inhibits the malignant progression of colorectal cancer cells by modulating oxidative stress.

Li C, Cheng X, Jiang Y
Oncology reports 2025 Jun;53(6)

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Role of DLAT in cuproptosis and autophagy in hippocampal tissue of PTSD rats with high-voltage electrical burns.

Ge C, Zhao X, Zhang J, Li P, Hao J, Lu M, Li C, Ge L, Tu L, Zhang Q
Burns : journal of the International Society for Burn Injuries 2025 Jun;51(5):107519

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Targeting the chromatin remodeler BAZ2B mitigates hepatic senescence and MASH fibrosis.

Tu C, Qian C, Li S, Lin DY, Liu ZY, Ouyang WG, Kang XL, Chen F, Song S, Cai SQ
Nature aging 2025 Jun;5(6):1063-1078

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The RNA Binding Protein Bcas2 is Required for Antibody Class Switch in Activated-B Cells.

Chen Y, Sun S, Lu C, Li Y, Fang B, Tang X, Li X, Yu W, Lei Y, Sun L, Zhang M, Sun J, Liu P, Luo Y, Zhao X, Zhan J, Liu L, Liu R, Huang J, Yi Z, Yu Y, Xiao W, Ding Z, Li L, Su D, Ren F, Cao C, Wang R, Shi W, Chen J
Exploration (Beijing, China) 2025 Jun;5(3):270015

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Demethylzeylasteral inhibits osteosarcoma cell proliferation by regulating METTL17-mediated mitochondrial oxidative phosphorylation.

Cao J, Zhang H, Wang C, He L, Li Y, Wang Z, Li X, Aziz F, Yang M, Zhu X
Toxicology and applied pharmacology 2025 Jun;499:117348

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MTMR7 attenuates the proliferation and migration of pulmonary arterial smooth muscle cells in pulmonary hypertension by suppressing ERK/STAT3 signaling.

Wang J, Xuan B, Song B, Wang T, Lan C, Guo W, Yang Y, Sun X
Molecular and cellular biochemistry 2025 Jun;480(6):3799-3812

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Punicalagin ameliorates lipopolysaccharide-induced inflammatory response in dental pulp cells via inhibition of the NF-κB/Wnt5a-ROR2 pathway.

Yang Y, Deng K, Jiang S, Guo X, Zhong Y, Wu B, Wei L
Immunopharmacology and immunotoxicology 2025 Jun;47(3):317-327

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Acyl-CoA thioesterase 8 induces gemcitabine resistance via regulation of lipid metabolism and antiferroptotic activity in pancreatic ductal adenocarcinoma.

Li BR, Wang T, Hu HF, Wu D, Zhou CJ, Ji SR, Zhuo QF, Li Z, Wang ZL, Fan GX, Jing DS, Yu CY, Qin Y, Chen XM, Xu JF, Xu XW
Acta pharmacologica Sinica 2025 Jun;46(6):1742-1756

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Crosstalk Between Th17 Cells and Renal Tubular Epithelial Cells Promotes Fibrotic Progression in IgA Nephropathy.

Zhou YN, Xia JK, Shi CR, He Y, Shang SL
Current medical science 2025 Jun;45(3):626-639

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Rifaximin Inhibits Small Bowel Angiodysplasia-Associated Angiogenesis by Attenuating LncRNA-HIF1A-AS2/miR-153-3p/HIF-1 α/Ang-2 Axis.

Peng S, Yin AN, Liao F, Zhao L
Current medical science 2025 Jun;45(3):574-584

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Memantine Exacerbates Trimethyltin-Induced Neurodegeneration and Delays Cognitive Impairment Recovery.

Onaka Y, Yamaguchi T, Yamasaki T, Morishige K, Yoneyama M
Neuropsychopharmacology reports 2025 Jun;45(2):e70014

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SUMOylation facilitates the stability of BCR-ABL to promote chronic myeloid leukemia progression.

Zhang L, Wang X, Hu D, Li S, Sun M, Liu Q, Feng H, Zhou M, Chen C, Zhou H, Ma S
Oncogene 2025 Jun;44(23):1844-1855

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Rbm24a dictates mRNA recruitment for germ granule assembly in zebrafish.

Zhang Y, Wang J, Fang H, Hu S, Yang B, Zhou J, Grifone R, Li P, Lu T, Wang Z, Zhang C, Huang Y, Wu D, Gong Q, Shi DL, Li A, Shao M
The EMBO journal 2025 Jun;44(11):3121-3149

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Irisin Alleviates Impaired Mitochondrial Fusion via Enhancing PKA/SIRT3/mTOR Pathway in Hepatic Steatosis.

Li J, Zhao Y, Wang Z, Ma A, Ni Y, Wu D, Zhou Y, Zhang N, Zhang L, Chang Y, Wang Q
Journal of gastroenterology and hepatology 2025 Jun;40(6):1616-1630

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β-Sitosterol Ameliorates Ulcerative Colitis Through Modulation of the AMPK/MLCK Anti-Inflammatory Pathway.

Zhang Y, Jin X, Xia H, Wu X, Chen W, Zhuang M, Tang S
Journal of biochemical and molecular toxicology 2025 Jun;39(6):e70287

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Hyperoside Protects Trastuzumab-Induced Cardiotoxicity via Activating the PI3K/Akt Signaling Pathway.

Wei S, Ma W, Xie S, Liu S, Xie N, Li W, Zhang B, Liu J
Cardiovascular drugs and therapy 2025 Jun;39(3):481-490

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PPM1D ameliorates Alzheimer's disease by promoting mitophagy.

Wang A, Zhang F, Zhang W, Gong J, Sun X
Experimental neurology 2025 Jun;388:115218

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Leucyl-tRNA synthetase regulates casein synthesis in dairy cows via the mTORC1-LAT1 pathway.

Ke Y, Du X, Chen B, Chen X, Song C, Fang X, Wang Y, Zhang C
Animal bioscience 2025 Jun;38(6):1259-1271

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2D Indium-Vacancy-Rich ZnIn(2)S(4) Nanocatalysts for Sonocatalytic Cancer Suppression by Boosting Cancer-Cell Pyroptosis.

Wang Z, Wang X, Fang H, Song X, Ding L, Chang M, Yan H, Chen Y
Advanced materials (Deerfield Beach, Fla.) 2025 Jun;37(24):e2414432

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Activation of GPER1 alleviates white matter injury by promoting microglia M2 polarization through EGFR/Stat3 pathway in intracerebral hemorrhage mice.

Zhang X, Mao J, Li H, Zhang C, Ge H, Zhong J
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2025 Jun;34(6):108315

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Inhibition of ferroptosis counteracts the advanced maternal age-induced oocyte deterioration.

Zeng W, Wang F, Cui Z, Zhang Y, Li Y, Li N, Mao Z, Zhang H, Liu Y, Miao Y, Sun S, Cai Y, Xiong B
Cell death and differentiation 2025 Jun;32(6):1071-1085

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Redox regulation of TRIM28 facilitates neuronal ferroptosis by promoting SUMOylation and inhibiting OPTN-selective autophagic degradation of ACSL4.

Liu W, Zhu Y, Ye W, Xiong J, Wang H, Gao Y, Huang S, Zhang Y, Zhou X, Zhou X, Ge X, Cai W, Zheng X
Cell death and differentiation 2025 Jun;32(6):1041-1057

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Quercetin-loaded exosomes delivery system prevents myopia progression by targeting endoplasmic reticulum stress and ferroptosis in scleral fibroblasts.

Zhao L, Dong X, Guo B, Song J, Bi H
Materials today. Bio 2025 Jun;32:101896

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A thermosensitive hydrogel with synergistic stromal targeting and antitumor immunity modulation for pancreatic cancer immunotherapy.

Zhao G, Guo F, Yan W, Qu Y, Yan C, Lv H, Li G, Zhao J, Xie H, Li Y, Tian T, Zhao Z
Materials today. Bio 2025 Jun;32:101882

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Sorafenib-loaded metal-organic framework nanoparticles for anti-hepatocellular carcinoma effects through synergistically potentiating ferroptosis and remodeling tumor immune microenvironment.

Yan Y, Hu J, Han N, Li HT, Yang X, Li LG, Xu Z, Xia F, Li J, Li TF, Chen R
Materials today. Bio 2025 Jun;32:101848

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CD20 targeted nanomedicine for GCB-diffuse large B-cell lymphoma through synergistic effects of apoptosis and ferroptosis.

Liu SX, Zhang JY, Zheng XY, Du YZ, Tong XM
Materials today. Bio 2025 Jun;32:101844

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Nanotube topography inhibits NLRP3 inflammasome activation by reducing microtubule glutamylation.

Mo D, Zhang W, Jia H, Ren M, Zeng X, He L, Xu X, Jing Z, Yang S, Chen T, Zhang H
Materials today. Bio 2025 Jun;32:101838

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Enhancing the antioxidant capacity of Fe single-atom nanozymes through local coordination manipulation for psoriasis treatment.

Xue H, Li Y, Ma X, Zhang Q, Zhu J, Ni X, Qiu J, Li Z, Mu Z
Materials today. Bio 2025 Jun;32:101830

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Dual-responsive nanoscale ultrasound contrast agent as an oxidative stress amplifier for enhanced DNA damage in BRCA-proficient ovarian cancer.

Zhang J, Wang X, Guo L, Xiao S, Meng D, Shang M, Sun X, Shi D, Zhao Y, Liu R, Huang S, Zeng X, Li J
Materials today. Bio 2025 Jun;32:101761

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Engineering exosome membrane disguised thermal responsive system for targeted drug delivery and controlled release across the blood-brain barrier.

Han Z, Huang H, Li B, Zhao R, Wang Q, Liu H, Xue H, Zhou W, Li G
Materials today. Bio 2025 Jun;32:101656

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Cryo-trojan mesenchymal stem cells as non-living tumor-homing supercarriers for enhanced drug delivery and immune activation in prostate cancer.

Wang C, Rong X, Zhang F, Mu X, Jiang J
Materials today. Bio 2025 Jun;32:101650

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Optically controllable nanoregulators enable tumor-specific pro-ferroptosis lipometabolic reprogramming for in-situ adjuvant-free vaccination.

Li M, Li Y, Yao X, Liu Y, Cai K, Yang H, Luo Z
Biomaterials 2025 Jun;317:123096

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Ionized Angelica polysaccharides derivatives slow tumor growth in vivo and induce the apoptosis of HepG2 cells via mitochondria death receptor-mediated pathways in vitro.

Yang Y, Wang J, Zhang Y, Xue W, Chen Y, Yue J, Wen Y, Feng R, Tan C
International journal of biological macromolecules 2025 Jun;315(Pt 1):144297

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Ubiquitin-specific protease 21 aggravates enterovirus 71 (EV71) infection by restricting Lys48-linked ubiquitination of EV71-2A protease.

Yang X, Tang M, Zang L, Hao P, Chen Y, Yuan Y, Miao Y, Zuo Y, Wu Z, Che Z, Ren T, Wu Q, Peng Y, Zhou W, Zheng H, Shi W
International journal of biological macromolecules 2025 Jun;314:144202

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Metastatic colorectal cancer cell preferentially secrets ribosomes, eukaryotic initiation factors and tRNA ligases via extracellular vesicles and aberrantly activate macrophages.

Yang LJ, Zhang J, Chen QP, Pan EG, Huang ZJ, Yin XF, Wang T, He QY, Wang Y
International journal of biological macromolecules 2025 Jun;311(Pt 4):143938

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Alhagi camelorum seed polysaccharide alleviates methylglyoxal-induced skin damage via antioxidant and anti-inflammatory actions.

Chen Q, Li M, Li Z, Mei M, Lin Y, Shu P, Zhu W
International journal of biological macromolecules 2025 Jun;311(Pt 3):143661

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mGluR5 in Pyramidal Neurons in the Hippocampus Mediates Chronic Stress-Induced Memory Deficits.

Lu HC, Du ZJ, Chen H, Guo T, Yang SC, Li X
CNS neuroscience & therapeutics 2025 Jun;31(6):e70477

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Pharmacological Inhibition of Mitochondrial Division Attenuates Simulated High-Altitude Exposure-Induced Memory Impairment in Mice: Involvement of Inhibition of Microglia-Mediated Synapse Elimination.

Chang P, Xu M, Zhu J, Bian J, Lu Y, Luo Q, Wang D, Zhu L
CNS neuroscience & therapeutics 2025 Jun;31(6):e70473

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LIMA1 Is a Prognostic Senescence-Inhibitory Gene in Head and Neck Squamous Carcinoma.

You Y, Du Z, Tian Z, Yu F, Li S, He J, Xiao M, Wang Y
Oral diseases 2025 Jun;31(6):1692-1703

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Curcumin activates the JAK-STAT signaling pathway to enhance the innate immune response against porcine epidemic diarrhea virus infection in vivo and in vitro.

Jiang Q, Liu X, Yuan J, Zhang S, Zhang Y, Kan Z, Niu Z, Zhang L, Hu X, Zhou Y, Wang J, Li F, Cao L, Zhang X, Lei C, Song Z
Veterinary microbiology 2025 Jun;305:110535

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Transcriptome profiling reveals that the host BRD4 protein facilitates African swine fever virus infection and suppresses inflammatory cytokine expression by downregulating transcriptional regulatory signaling pathways.

Wu M, Yang J, Tian Z, Sun H, Zhang Z, Luo J, Guan G, Yin H, Niu Q, Hao R
Veterinary microbiology 2025 Jun;305:110498

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Nrf2-and p53-inducible REDD2/DDiT4L/Rtp801L confers pancreatic β-cell dysfunction, leading to glucose intolerance in high-fat diet-fed mice.

Yamada Y, Urakawa N, Tamiya H, Sakamoto S, Takahashi H, Harada N, Kitakaze T, Izawa T, Matsumua S, Yoshihara E, Inui H, Mashimo T, Yamaji R
The Journal of biological chemistry 2025 Jun;301(6):110271

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DEP domain‑containing 1 is a prognostic biomarker associated with the cell cycle in gliomas.

Li H, Liu Y, Zhang H, Wang X
Oncology letters 2025 Jun;29(6):276

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Charged multivesicular body protein 4C promotes the progression of cervical cancer through the HPV E6/miR‑543 axis.

Liu RC, Ji YM, Huang J, Du YP, Zhong YM, Sheng XJ
Oncology letters 2025 Jun;29(6):275

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Succinate Accumulation Accelerates Oxidative Stress to Promote Pulmonary Epithelial Cell Apoptosis During Lung Ischemia-Reperfusion Injury.

Wang W, Feng N, Shi Q, Yang J, Tan Y, Zhou W, Shi M
Journal of cellular and molecular medicine 2025 Jun;29(11):e70645

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Psychological stress-induced ALKBH5 deficiency promotes tumour innervation and pancreatic cancer via extracellular vesicle transfer of RNA.

Chen Z, Zhou Y, Xue C, Zeng L, Deng S, Xu Z, Li M, Zhao H, He X, Liu S, Liu J, Liu S, Zhao S, Zhang S, Peng X, Wu X, Bai R, Zhuang L, Wu S, Zhang J, Lin D, Huang X, Zheng J
Nature cell biology 2025 Jun;27(6):1035-1047

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Elevated TGF-β1 impairs synaptic and cognitive function through activation of Smad2/3-Sp1 pathway in AngII-related hypertension.

Guo C, Li W, Li Y, Liu Y, Mahaman YAR, Wang J, Luo H, Liu R, Shen H, Wang X
EMBO reports 2025 Jun;26(12):3162-3186

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mTOR controls ependymal cell differentiation by targeting the alternative cell cycle and centrosomal proteins.

Bankolé A, Srivastava A, Shihavuddin A, Tighanimine K, Faucourt M, Koka V, Weill S, Nemazanyy I, Nelson AJ, Stokes MP, Delgehyr N, Genovesio A, Meunier A, Fumagalli S, Pende M, Spassky N
EMBO reports 2025 Jun;26(12):3075-3105

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Alterations of retinal autophagy after a blast simulated microgravity in rats.

Liu M, Wang Y, Ren F, Zhang W, Zheng H, Shi Q, Zhang R, Gao C, Luo L, Gu J, Nie C
Experimental eye research 2025 Jun;255:110366

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Tributyltin affects the growth of ovarian granulosa cells in polycystic ovary syndrome by upregulating YY1-mediated CDKN1C via the PI3K/AKT pathway.

Dong S, Liu Y, Yang Z
Reproductive biology 2025 Jun;25(2):101020

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Circular RNA Telomerase Reverses Endothelial Senescence in Progeria.

Qin W, Castillo KD, Li H, Nguyen TKC, Kiss DL, Cooke JP, Mojiri A
Aging cell 2025 Jun;24(6):e70021

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Negative Effect of Gst-35 on the Health Span of Caenorhabditis elegans Through Lysosomal Dysfunction via the Pmk-1 and Skr Genes.

Gao Y, Zhang X, Wei C, Lin H, Wu M, Ma B, Jiang J, Li S, Wang H
Aging cell 2025 Jun;24(6):e70016

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Acetylation of H3K18 activated by p300 promotes osteogenesis in human adipose-derived mesenchymal stem cells.

Zeng L, Chen C, Xiong Y, Liu Y, Huang M, Ye J, Zhong J, Peng W
Biochemical pharmacology 2025 Jun;236:116901

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Histone lactylation facilitates MCM7 expression to maintain stemness and radio-resistance in hepatocellular carcinoma.

Liu Z, Han J, Su S, Zeng Q, Wu Z, Yuan J, Yang J
Biochemical pharmacology 2025 Jun;236:116887

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Natural small molecule thymoquinone increases the chemosensitivity of glioblastoma to temozolomide through inhibiting Wnt/β-catenin signaling pathway to downregulate MGMT expression: In vitro and in vivo validation.

Bai P, Wang P, Ren T, Tang Q, Lin Z, Zhang N, Zhao L, Zhong R, Sun G
Biochemical pharmacology 2025 Jun;236:116886

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Irisin alleviates steroid-induced vascular dysfunction by regulating the αVβ5-c-Abl-Caveolin-1 signaling pathway.

Fang L, Li W, Zhao H, Wang W, Gao H, Wang P, Zhang X, Lv R, Xu F, Chen J, Lyu L, Chen Y
Biochemical pharmacology 2025 Jun;236:116870

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The mitochondrial protease ClpP is a promising target for multiple myeloma treatment.

Liu X, Gu J, Liu S, Huang J, Li L, Wang F, He S, Mi Z, Zhang Y, Wen J, Gao Q, Yang H, Feng Y, Luo H, Zhai X, Zhang L, Zheng Y, Luo Y, Niu T
Biochemical pharmacology 2025 Jun;236:116855

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Mild and ultrafast GLORI enables absolute quantification of m(6)A methylome from low-input samples.

Sun H, Lu B, Zhang Z, Xiao Y, Zhou Z, Xi L, Li Z, Jiang Z, Zhang J, Wang M, Liu C, Ma Y, Peng J, Wang XJ, Yi C
Nature methods 2025 Jun;22(6):1226-1236

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Mitochondria-localized MBD2c facilitates mtDNA transcription and drug resistance.

Hao Y, Zhou Z, Liu R, Shen S, Liu H, Zhou Y, Sun Y, Mao Q, Zhang T, Li ST, Liu Z, Chu Y, Sun L, Gao P, Zhang H
Nature chemical biology 2025 Jun;21(6):926-938

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Salmonella Typhimurium persistently infects host via its effector SseJ-induced PHB2-mediated mitophagy.

Sun D, Gou H, Zhang Y, Li J, Dai C, Shen H, Chen K, Wang Y, Pan P, Zhu T, Xu C, Shan T, Liao M, Zhang J
Autophagy 2025 Jun;21(6):1228-1244

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Astragaloside IV Relieves Mitochondrial Oxidative Stress Damage and Dysfunction in Diabetic Mice Endothelial Progenitor Cells by Regulating the GSK-3β/Nrf2 Axis.

Zou X, Liu X, Qu W, Zhang X, Zou Y, Lin X, Hu W, Gao R, He Y, Zhou S, Huang Y, Xiong W
Applied biochemistry and biotechnology 2025 Jun;197(6):3964-3981

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S-phase kinase-associated protein 1 inhibits orbital fibroblasts adipogenesis to improve thyroid-associated ophthalmopathy (TAO).

Lu S, Xiong W, Yi J, Liu S, Zhang F
Biochimica et biophysica acta. Molecular cell research 2025 Jun;1872(5):119937

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Glabridin ameliorates hemorrhagic shock induced acute kidney injury by activating Nrf2/HO-1 pathway.

Shu L, Zhang Z, Wang N, Yin Q, Chao Y, Ge X
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167810

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Gen-17, a beta-methyl derivative of Genipin, attenuates LPS-induced ALI by regulating Keap1-Nrf2/HO-1 and suppressing NF-κB and MAPK-dependent signaling pathways.

Zhu YS, Shah SAA, Yang BY, Fan SS, He L, Sun YR, Shang WB, Qian Y, Zhang X
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167770

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Both carvedilol and cimetidine alleviate cisplatin-induced nephrotoxicity via downregulating OCT2.

Wu H, Ning Y, Sun Z, Ji J, Lu M, Jiao X, Xu X, Ding X, Cheng X, Yu X
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167754

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Liposome of Phlorizin promote the repair of carotid atherosclerosis in rats by regulating inflammation and the Nrf2 signaling pathway.

Wu X, Ding C, Liu X, Ding Q, Zhang S, Wang Y, Zhao T, Liu W
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Jun;1870(5):159613

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rTMS ameliorates CUMS-induced anxiety-depression-like behaviour and cognitive dysfunction in rats by modulating the COX-2/PGE2 signalling pathway.

Pei Y, Liu H, Lang J, Chen Y, Zhang F, Hao R, Li J, Gu S, Peng Q, Song J, Zhang Z
Journal of psychiatric research 2025 Jun;186:116-128

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Aloe Vera flowers extracts inhibit melanogenesis via activating PI3K/Akt signaling pathway: Network pharmacology and experimental validation.

Li J, Zou W, Li M, Yan Y, Yu Y, Li X, Ma YL
Fitoterapia 2025 Jun;183:106530

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AKAP14 is dispensable for mouse fertility.

Xu Z, Hussain A, Jiang H, Zhang H, Raza Y, Mustafa G, Ye J, Yuan B, Yang B, Shi Q
Cells & development 2025 Jun;182:204032

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Neferine reduces synovial inflammation and cardiac complications in a collagen-induced arthritis mouse model via inhibiting NF-κB/NLRP3 inflammasome axis.

Cao J, Zhang H, Ni Y, Ning X
Molecular immunology 2025 Jun;182:117-125

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Neuroprotective effects and mechanisms of the YiQiWenYangSanHan formula on Parkinson's disease mice.

Liu J, Di D, Sun S, Sun Y, Zhou S, Liu J, Qin Z, Yang X, Wang X, Xu Z, Zhu B, Wu H
IBRO neuroscience reports 2025 Jun;18:528-538

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Neu1-deficient zebrafish cells exhibit reduced Edwardsiella piscicida infection due to altered lysosomal exocytosis and membrane dynamics.

Ishii M, Tsurusaki A, Komatsu M, Shiozaki K
Fish & shellfish immunology 2025 Jun;161:110273

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Litopeidin(28-51), a novel antimicrobial peptide from Litopenaeus vannamei, combats white spot syndrome virus infection through direct virus lysis and immunomodulatory effects.

Meng XZ, Duan Y, Bai Y, Zhang W, Zhang C, Wang KJ, Chen F
Fish & shellfish immunology 2025 Jun;161:110243

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GPR39 Agonist TC-G 1008 Promoted Mitochondrial Biogenesis and Improved Antioxidative Capability via CREB/PGC-1α Pathway Following Intracerebral Hemorrhage in Mice.

Zhang Z, Yuan Y, Zhang X, Gu L, Tang Y, Zhao Y, Dai J, Tao Y, Xie Z
Translational stroke research 2025 Jun;16(3):625-644

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RBM14 enhances transcriptional activity of p23 regulating CXCL1 expression to induce lung cancer metastasis.

Zhang W, Peng Y, Zhou M, Qian L, Che Y, Chen J, Zhang W, He C, Qi M, Shu X, Tian M, Tian X, Tian Y, Deng S, Wang Y, Huo X, Yu Z, Ma X
Acta pharmaceutica Sinica. B 2025 Jun;15(6):3059-3072

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C1QL1 regulates auditory nerve fibers growth via ELMO1-DOCK180-RAC1 integrin.

Chen M, Qi Y, Gong S
Acta oto-laryngologica 2025 Jun;145(6):476-482

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Integrated network pharmacology and experimental validation to elucidate the mechanism of celastrol in mitigating sepsis-induced acute lung injury in mice.

Zhu D, Zhang J, Huang X, Wei N, Jiang J, Li J, Liu L, Liu Y, Zhou J, Jia J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156678

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Diosgenin alleviates lipid accumulation in NAFLD through the pathways of ferroptosis defensive and executive system.

Wang L, Yu H, Wang D, Yin G, Chen S, Zhang X, Yu W, Meng D, Liu H, Jiang W, Zhang F
The Journal of nutritional biochemistry 2025 Jun;140:109886

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An Energy Metabolism Nanoblocker for Cutting Tumor Cell Respiration and Inhibiting Mitochondrial Hijacking from Cytotoxic T Lymphocyte.

Leng X, Yang Y, Jiang T, Zheng J, Zhang L, Huang J, Xu H, Fang M, Li X, Wang Z, Ge M, Lin H
Advanced healthcare materials 2025 Jun;14(16):e2405174

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Ellagic acid ameliorates atherosclerosis by inhibiting PCSK9 through the modulation of FoxO3 and HNF1α.

Wang LT, Yin HL, Jin YM, Hu DD, Yang XX, Sheng J, Huang YW, Wang XJ
Nutrition (Burbank, Los Angeles County, Calif.) 2025 Jun;134:112717

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Unfolded protein response-activated NLRP3 inflammasome contributes to pyroptotic and apoptotic podocyte injury in diabetic kidney disease via the CHOP-TXNIP axis.

Cao Y, Hu L, Chen R, Chen Y, Liu H, Wei J
Cellular signalling 2025 Jun;130:111702

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Pdia3 deficiency exacerbates intestinal injury by disrupting goblet and Paneth cell function during ischemia/reperfusion.

Zhan Y, Deng Q, Jia Y, Chen Z, Zhao X, Ling Y, Qiu Y, Wang X, Wang F, He M, Huang W, Shen J, Wen S
Cellular signalling 2025 Jun;130:111682

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N-acetylglucosaminyltransferase V attenuates myocardial infarction by mediating the insulin-like growth factor 1 receptor signaling pathway.

Chang T, Jin Y, Fan C, Wang H, Jin L, Shi Y, Li H, Wang J, Xu M
Journal of translational internal medicine 2025 Jun;13(3):281-294

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Mitochondrial Ca(2+) uniporter b (MCUb) regulates neuronal Ca(2+) dynamics and resistance to ischemic stroke.

Nguyen T, Lin Z, Dhanesha N, Patel RB, Lane M, Walters GC, Shutov LP, Strack S, Chauhan AK, Usachev YM
Cell calcium 2025 Jun;128:103013

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MAT2A Knockdown Enhances Recombinant Protein Expression in Transgenic CHO Cells Through Regulation of Cell Cycle.

Gao YP, Lu JT, Zhang HJ, Cui ZM, Guo Y, Zhang X, Wang W, Qiu LL, Wang XY, Wang TY, Jia YL
Biotechnology and bioengineering 2025 Jun;122(6):1461-1471

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The novel protein C variant p.C101F results in early intracellular degradation that drives type I protein C deficiency.

Yui R, Nagaya S, Yasuda I, Togashi T, Kikuchi Y, Saito K, Meguro-Horike M, Horike SI, Kawasaki H, Nishikii H, Morishita E
International journal of hematology 2025 Jun;121(6):774-781

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S-ketamine Alleviates Neuroinflammation and Attenuates Lipopolysaccharide-Induced Depression Via Targeting SIRT2.

Lin C, Zhou X, Li M, Zhang C, Zhai H, Li H, Wang H, Wang X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(23):e2416481

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Nuclear-Localized BCKDK Facilitates Homologous Recombination Repair to Support Breast Cancer Progression and Therapy Resistance.

Liu H, Feng J, Pan T, Zhang P, Ye L, Jiang Z, Zhou Z, Mao Q, Li J, Yang X, Gao P, Huang D, Zhang H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(22):e2416590

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Deciphering the Metabolic Impact and Clinical Relevance of N-Glycosylation in Colorectal Cancer through Comprehensive Glycoproteomic Profiling.

Liu G, Chen L, Zhao J, Jiang Y, Guo Y, Mao X, Ren X, Liu K, Mei Q, Li Q, Huang H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2415645

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MeCP2 Lactylation Protects against Ischemic Brain Injury by Transcriptionally Regulating Neuronal Apoptosis.

Sun M, Zhang Y, Mao R, Chen Y, Liu P, Ye L, Xu S, Jia J, Shu S, Li H, Yin Y, Xia S, Chen Y, Xu Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2415309

---

CXCL13 Damages Blood Spinal Cord Barrier by Promoting RNF6/Sqstm1-Ubiquitination Induced Autophagy in Experimental Allergic Encephalomyelitis.

Han J, Hong R, Cao C, Feng W, Zhuang W, Wang G, Tang J, Yang Y, Zhang C, Zhou A, Qu X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2414550

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KLF1 Promotes Cardiomyocyte Proliferation and Heart Regeneration Through Regulation of Wnt/β-Catenin Signaling Pathway.

Hao Y, Zhang X, Ran S, Li Y, Ye W, Wang S, Li X, Luo Z, Zhao J, Zong J, Zheng K, Li R, Zhang H, Lai L, Huang P, Zou Z, Zhan W, Yue Z, Wu J, Xia J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2413964

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Apelin-13 Protects Against Airway Inflammation, Oxidative Stress, and Epithelial-Mesenchymal Transition in a Chronic Asthma Model.

Sun H, Wang A, Shi N
Chemical biology & drug design 2025 Jun;105(6):e70142

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A mass-producible macaque model displays a durable Alzheimer-like cognitive deficit and hallmark amyloid-β/tau/neurofilament light chain pathologies.

He F, Shi WJ, Liu W, Fan JX, He ZG, Zhang YQ, Xiao J, Ruan WW, Gai YK, Zhang HL, Yang BB, Qin Y, Wang H, Li J, Wang JL, Liu S, Shi LP, Chen ZX, Jiang WJ, An N, Xue PJ, Wang ZH, Yang RJ, Tian PY, Chen Z, Xiao L, Yang ZS, Feng KB, Tan WY, Sun ZM, Xu W, Shu H, Wang JZ
Journal of Alzheimer's disease : JAD 2025 Jun;105(4):1432-1446

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Duck plague virus UL47 gene affects the release and cell-to-cell spread of the virus and its deletion strains can provide strong protection for ducks.

Cui Y, Chen S, Wang M, Zhang W, Yang Q, Ou X, Sun D, He Y, Tian B, Wu Z, Zhang S, Huang J, Wu Y, Zhao X, Zhu D, Chen S, Liu M, Jia R, Cheng A
Poultry science 2025 Jun;104(6):105092

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CIP2A promotes inflammation and exacerbates osteoarthritis by targeting CEMIP.

Su J, Sun X, Chen X, Wei K, Luo D, Yang S, Zhang C, Xu J, Deng Z
Cellular & molecular biology letters 2025 Jun 9;30(1):67

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Lactate programs PBX1 lactylation and mesangial proliferation in lupus nephritis.

Liu E, Weng C, Yan C, Zhu X, Li X, Liu M, Wen Z, Liu Z
JCI insight 2025 Jun 9;10(11)

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NOTCH1-STAT3 signaling axis regulates astrocytic differentiation of hippocampal neural stem/progenitor cells.

Jin N, Lee J, Park SY, Han JS
Biochemical and biophysical research communications 2025 Jun 8;765:151844

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Cytotoxicity induced by Aeromonas schubertii is orchestrated by a unique set of type III secretion system effectors.

Michova H, Pliva J, Jirsova A, Jurnecka D, Kamanova J
Veterinary research 2025 Jun 8;56(1):113

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Can linc00968 Regulate SH-SY5Y Cell Apoptosis Induced by Amyloid beta Neurotoxicity?

Kurt S, Karagur ER, Kavak DE, Kizildag S
Molecular biology reports 2025 Jun 6;52(1):557

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PFOS causes lysosomes-regulated mitochondrial fission through TRPML1-VDAC1 and oligomerization of MCU/ATP5J2.

Yang W, Li Y, Feng R, Liang P, Tian K, Hu L, Wang K, Qiu T, Zhang J, Sun X, Yao X
Journal of hazardous materials 2025 Jun 5;489:137685

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Unveiling the mechanisms of mechanical loading-induced knee osteoarthritis through transcriptomics.

Wu Y, Li A, Sun N, Jiang Z, Li Y, Zhou Z, Li X, Zhao D, Leng X, Dong H
International immunopharmacology 2025 Jun 5;157:114785

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MCTR1 ameliorates LPS-induced lung injury by inhibiting neutrophil reverse transendothelial migration.

Cheng Y, Xiao Y, Wang DM, Liu K, Yang X, Zheng CX, He ZB, Guo ZY, Yang Y
International immunopharmacology 2025 Jun 5;157:114777

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Alisol B alleviates MASLD by activating liver autophagy and fatty acid oxidation via Ces2a.

Zhang C, Chen L, Jiang Y, Qiu J, Lin Y, Ren G, Xu F, Xi J, Yu Z, Rong X, Dou X
International immunopharmacology 2025 Jun 5;157:114768

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Enzymatic Synthesis and Evaluation of Eight Methylated Quercetin Products: In Vitro Chemical Properties and Adipogenesis Regulation.

Ang B, Yang T, Jiang H, Cheng Y, Chen Y, Qie X, Yin L, Wang T, Chen Q, Wang Z, Zeng M, Adhikari B, He Z, Chen J
Journal of agricultural and food chemistry 2025 Jun 4;73(22):13973-13984

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Probiotic Combination of Limosilactobacillus fermentum HF07 and Lactococcus lactis HF08 Targeting Gut Microbiota-Secondary Bile Acid Metabolism Ameliorates Inflammation and Intestinal Barrier Dysfunction in Aging Colitis.

Liu X, Guan K, Ma Y, Jiang L, Li Q, Liu Y, Mao K, Wang R
Journal of agricultural and food chemistry 2025 Jun 4;73(22):13439-13454

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Pelargonidin-3-O-galactoside Alleviates Acute Lung Injury Induced by Klebsiella pneumoniae by Targeting CD38-Mediated Pyroptosis.

Jiang F, Jiang J, Sun Y, Meng L, Chen J, Liang L, Wang X, Zhang H, Meng M, Yuan B, He S, Li R
Journal of agricultural and food chemistry 2025 Jun 4;73(22):13415-13426

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MBD2 promotes B cell differentiation and BCR signaling in systemic lupus erythematosus by regulating the LEF-1-PTEN-PI3K axis.

Jing Y, Zhang Y, Wang X, Wang Y, Hu Y, Wen B, Dai X, Duan X, Li H, Dong S, Yan Z, Fan Y, Wang CY, Liu X, Zhang R
Cell death & disease 2025 Jun 4;16(1):433

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SOX3 facilitates granulosa cell proliferation and suppresses cell apoptosis through modulating PI3K/AKT pathway by targeting SPP1.

Cai R, Li C, Shi W, Xie F, Fan M, Zhang H, Liu Z, Chen Y, Hong Q
Cellular and molecular life sciences : CMLS 2025 Jun 30;82(1):266

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Apelin Alleviated Endothelial-To-Mesenchymal Transition via Increasing BKCa in Diabetic Nephropathy.

Fan C, Liu Y, Chang J, Huang M, Gao Z, Wang H, Zheng X, Li M, Xu J, Yin J, Zeng X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 30;39(12):e70747

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HELQ Maintains Genome Stability of Primordial Germ Cells by Inhibiting LINE-1 Expression.

Cao L, Ren J, Kong Z, Hu M, Zhang Y, Chen ZJ, Qin Y, Yang Y, Zhao S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 30;39(12):e70720

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Mitigation of Ferroptosis in Diabetic Kidney Disease Through Mesenchymal Stem Cell Intervention via the Smad2/3/METTL3/S1PR1 Axis.

Huang LL, Hou YY, Yang J, Liao XN, Ma JS, Wang WC, Quan YX, Jiang HY, Bai YH
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 30;39(12):e70714

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Hypoxia Exposure Promotes Th17 Cell Differentiation Through Activin A-PKM2 Axis to Exacerbate Autoimmune and Autoinflammatory Diseases.

Li Y, He M, Xu J, Liu J, Xiao C, Hu Y, Chen H, Chang J, Liu X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 30;39(12):e70696

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GCRV-II Triggers B and T Lymphocyte Apoptosis via Mitochondrial ROS Pathway.

Wang J, Dong WJ, Wu CS, Tian TT, Zhang XJ, Zhang YA
Viruses 2025 Jun 30;17(7)

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O-GlcNAcylation-mediated endothelial metabolic memory contributes to cardiac damage via small extracellular vesicles.

Ding M, Shi R, Du Y, Chang P, Gao T, De D, Chen Y, Li M, Li J, Li K, Cheng S, Gu X, Li J, Zhang S, Feng N, Liu J, Jia M, Fan R, Pei J, Gao C, Fu F
Cell metabolism 2025 Jun 3;37(6):1344-1363.e6

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Pyruvate kinase M2 activation reprograms mitochondria in CD8 T cells, enhancing effector functions and efficacy of anti-PD1 therapy.

Mortazavi Farsani SS, Soni J, Jin L, Yadav AK, Bansal S, Mi T, Hilakivi-Clarke L, Clarke R, Youngblood B, Cheema A, Verma V
Cell metabolism 2025 Jun 3;37(6):1294-1310.e7

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Fecal microbiota transplantation from Helicobacter pylori carriers following bismuth quadruple therapy exacerbates alcohol-related liver disease in mice via LPS-induced activation of hepatic TLR4/NF-κB/NLRP3 signaling.

Gao H, Bai H, Su Y, Gao Y, Fang H, Li D, Yu Y, Lu X, Xia D, Mao D, Luo Y
Journal of translational medicine 2025 Jun 3;23(1):627

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PA1b-like peptides alleviate mitochondrial dysfunction induced by glucose toxicity through interaction with VDAC1 in β-cells.

Huang H, Zeng X, Zhang L, Cheng H, Hu K, Shang X, Yao C
Food & function 2025 Jun 3;16(11):4325-4342

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Emodin influences pyroptosis-related Caspase 1-GSDMD axis alleviated cerebral ischemia-reperfusion injury in rats.

Zhang G, Hu X, Qian J, Shi Y, Ling Z, Xu P, Xu Z, Zhang J, Liang T
Scientific reports 2025 Jun 3;15(1):19397

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Exercise-induced irisin ameliorates cognitive impairment following chronic cerebral hypoperfusion by suppressing neuroinflammation and hippocampal neuronal apoptosis.

Xiao W, Yang Y, Bai L, Yang P, Li R, Yang D, Li F, Quan L, Liang Q, Yan Y, Qi T, Liang F
Journal of neuroinflammation 2025 Jun 28;22(1):168

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MYC promotes group 3 medulloblastoma cell proliferation and alleviates ROS-induced cell death by upregulating transketolase.

Wang S, Zhang D, Wang C, Liu Y
Acta neuropathologica communications 2025 Jun 28;13(1):139

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MMAE-Based Peptide-Drug Conjugates Targeting GPC3 for Precision Chemoradiotherapy in Hepatocellular Carcinoma.

Pan S, Sha L, Wu F, Wang N, Yang H, Zhang X, Zhou S, Hu C, Ding G, Xu J, Li K, Guo G, Li Y, Cao Z, Zhou Y, Pan S, Zhang W
Journal of medicinal chemistry 2025 Jun 26;68(12):12950-12968

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Discovery of TBK1Molecular Glue Degraders as a Potential Strategy for the Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD).

Guo J, Tang H, Zhao W, Li Y, Song S, Feng F, Huang S, Wang X, Zhou Y, Pei J, Guo D, Xie H, Lu X
Journal of medicinal chemistry 2025 Jun 26;68(12):12862-12880

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Caveolin-1-Mediated Blood-Brain Barrier Disruption via MMP2/9 Contributes to Postoperative Cognitive Dysfunction.

Li X, Ding W, Zhang X, Tang X, Zheng Y, Ma Y, Bao X, Kang X, Zhu S
Neurochemical research 2025 Jun 26;50(4):210

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Multi-Omics Integration: Predicting Progression and Optimizing Clinical Treatment of Hepatocellular Carcinoma Through Malignant-Cell-Related Genes.

Wang Q, Cheng L, Yan H, Yuan J
International journal of molecular sciences 2025 Jun 26;26(13)

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Endoplasmic reticulum stress induces trophoblast pyroptosis via regulating CYLD during labor initiation.

Zhang X, Yang M, Lv D, Zhang Y, Xie Y, He M, Fan Y, Li X, Jallow F, Li F, Deng D
Placenta 2025 Jun 26;167:204-215

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TAMs-derived SPP1, regulated by HIF-1α/STAT3 signaling pathway, influences colorectal cancer malignant progression by activation of EMT via integrin αvβ3.

Qu Y, Wang X, Li J, Luo H, Liu H, Wang T, Han X
International immunopharmacology 2025 Jun 26;159:114947

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Mitigating PCOS progression: The protective effect of C-phycocyanin on ovarian granulosa cell pyroptosis via the NRF2/NLRP3/GSDMD pathway.

Zhang J, Chen Y, Han B, Liu Y, Li X, Yang J, Liu Y, Cao Y, Liang D, Yu B
International immunopharmacology 2025 Jun 26;159:114917

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miR-29a nanoparticles improve chronic insomnia by regulating microglia activation and hippocampal neuronal cell pyroptosis through PER2/NF-κB axis.

Hou D, Hu Y, Li H, Yang G
International immunopharmacology 2025 Jun 26;159:114882

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Chondrocyte-targeted α-Solanine through HIF-1α regulating glycolysis to reduce the ferroptosis of chondrocyte in osteoarthritis.

Li W, Liu Y, Wei M, Yang Z, Tang H, Huang W
International immunopharmacology 2025 Jun 26;159:114841

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Quercetin, as a Nutritional Supplement, Protects against Iron Overload-Induced Testicular Dysfunction via Inhibiting Ferroptosis.

Yuan W, Ji G, Wang X, Li W, Sun Z, Wei Z, Shi X, Hu H
Journal of agricultural and food chemistry 2025 Jun 25;73(25):15579-15595

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Leucine-rich pentatricopeptide repeat-containing protein (LRPPRC)-stabilized lncRNA small nucleolar RNA host gene 15 (Snhg15) modulates hematopoietic injury induced by γ-ray irradiation via m(6)A modification.

Zhang S, Cheng Y, Gao Y, Xu F, Wang Y, Zhang J, Shang Y, Li D, Fan S
Molecular biomedicine 2025 Jun 25;6(1):44

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Therapeutic Potential of CHCHD2 in Ischemia-Reperfusion Injury: Mechanistic Insights into Nrf2-Dependent Antioxidant Defense in HK2 Cells.

Hao Y, Zhou X
International journal of molecular sciences 2025 Jun 25;26(13)

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A protein complex in the extreme distal tip of vertebrate motile cilia controls their organization, length, and function.

Hong J, Lee C, Madhu G, Papoulas O, Atayeter E, Hoogerbrugge G, Pan J, Takagishi M, Manzi N, Dickinson DJ, Horani A, Brody SL, Marcotte E, Prakash VN, Park TJ, Wallingford JB
bioRxiv : the preprint server for biology 2025 Jun 25;

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ENPP1 governs the metabolic regulation of effector T cells in autoimmunity by detecting cytosolic mitochondrial DNA.

Ji H, Jiang W, Zhang J, Liu M, Su D, Lei J, Li L, Zheng M, Liu T, Liu Z, Cao Q, Xu L, Xiong S, Wen Z
Cell reports 2025 Jun 24;44(6):115851

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Glycerophospholipid metabolism licenses IgE-mediated mast cell degranulation.

Xia Y, Bin P, Zhou Y, Zhao M, Zhang J, Zhong W, Wang N, Wang B, Ren W
Cell reports 2025 Jun 24;44(6):115742

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Advantages of cell proliferation and immune regulation in CD146+NESTIN+ HUMSCs: insights from single-cell RNA sequencing.

Huang P, Qin X, Fan C, Zhong H, Wang M, Chen F, Liao M, Zheng N, Wang H, Lin B, Ma L
Stem cells (Dayton, Ohio) 2025 Jun 24;43(7)

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STAT3-controlled CHI3L1/SPP1 positive feedback loop demonstrates the spatial heterogeneity and immune characteristics of glioblastoma.

Yu W, Gui S, Peng L, Luo H, Xie J, Xiao J, Yilamu Y, Sun Y, Cai S, Cheng Z, Tao Z
Developmental cell 2025 Jun 23;60(12):1751-1767.e9

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Astragaloside's Role in Microglial Neuroinflammation: A Multi-Method Study Combining Experimental and Computational Analyses.

Ou D, Li J, Shi Y, Liu X, Deng N, Peng L, Li Y, Xiong T, Bai Y, Zhang W, Ding H
Neurochemical research 2025 Jun 23;50(4):205

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Pyridine-bis(benzimidazole) induces DNA damage at G-quadruplex loci and promotes synthetic lethality with DNA repair inhibition.

Yan J, Bu L, Wang Y, Yao H, Li G, Zheng K, Huang J
Nucleic acids research 2025 Jun 20;53(12)

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IGFBP2 Modulates Trophoblast Function and Epithelial-Mesenchymal Transition in Preeclampsia via the PI3K/AKT Signaling Pathway.

Meng S, Qin Y, Lyu C, Wang S
Current issues in molecular biology 2025 Jun 20;47(7)

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Computational design of diverse nuclear factor erythroid 2 activators with cellular antioxidative activity.

Yuwen M, Gao X, Ba J, Wu J, Kang J, Ye S, Zhu C
iScience 2025 Jun 20;28(6):112621

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ISCU-p53 axis orchestrates macrophage polarization to dictate immunotherapy response in esophageal squamous cell carcinoma.

Luo J, Zhang X, Liang Z, Zhuang W, Jiang M, Ma M, Peng S, Huang S, Qiao G, Chen Q
Cell death & disease 2025 Jun 20;16(1):462

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CRTC2 Forms Co-Condensates with YTHDF2 That Enhance Translational Efficiency of m6A-Modified mRNAs to Drive Hepatocarcinogenesis and Lenvatinib Resistance.

Wang M, Zou F, Wang S, Yang Y, Xia C, Chen L, Liu B, Li L, Li MJ, Li H, Song W, Niu R, Yuan Z, Yang J, Li X, Chen K, Wu Z, Mi Z
Cancer research 2025 Jun 2;85(11):2046-2066

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PRMT5 Regulates Senescence in Retinal Ganglion Cells by Targeting the Wnt/β-Catenin Signaling Cascade.

Zhang Y, Huang H, Zhong H, Zhang Y, He S, Guo Y, Wang Y, Huang P, Huang S, Zhong Y
Investigative ophthalmology & visual science 2025 Jun 2;66(6):8

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Corneal Sensory Denervation Causes Epithelial Ferroptosis and Delayed Healing in Mice.

Wang N, Li Y, Wang X, Yang L, Zhang J, Cheng J, Jiang X, Qi X, Wei C, Zhou Q, Li Y, Li S
Investigative ophthalmology & visual science 2025 Jun 2;66(6):28

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SLC6A6-Mediated Taurine Uptake Sustains Corneal Epithelial Stem/Progenitor Cell Function to Counteract Age-Related Dysfunction.

Li Y, Xie F, Yang L, Wang X, Zhang Y, Ge H, Wang M, Cao R, Zhou Q, Li Y
Investigative ophthalmology & visual science 2025 Jun 2;66(6):25

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Scutellarin prevents obesity-induced renal fibrosis via reduced activation of AP-1.

Yi H, Jiang Y, Li W, Shen L, Zhang W, Li S, Xu Y, Li F
Journal of translational medicine 2025 Jun 2;23(1):611

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Identification of CD84 as a potent survival factor in acute myeloid leukemia.

Zhu Y, Murtadha M, Liu M, Caserta E, Napolitano O, Nguyen LXT, Wang H, Moloudizargari M, Nigam L, Tandoh T, Wang X, Pozhitkov A, Su R, Lin X, Estepa MD, Pillai R, Song J, Sanchez JF, Fu YH, Zhang L, Li M, Zhang B, Li L, Kuo YH, Rosen S, Marcucci G, Williams JC, Pichiorri F
The Journal of clinical investigation 2025 Jun 2;135(11)

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G0S2: a potential target for NSCLC identified through prognostic models from multi-Omic analysis of regulatory T cell metabolic genes.

Zhou M, Liu M, Hu Y, Xu Z, Cai L, Bai Y, Su L, Sun L
NPJ precision oncology 2025 Jun 19;9(1):198

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Cold-blooded vertebrates evolved regulatory B cells to participate in inflammatory diseases.

Wang J, Dong WJ, Tian TT, Wu CS, Zhang XY, Hu YZ, Pan YR, Han XQ, Li J, Tafalla C, Zhang YA, Zhang XJ
Cell communication and signaling : CCS 2025 Jun 19;23(1):295

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Development of potent and selective tetrahydro-β-carboline-based HDAC6 inhibitors with promising activity against triple-negative breast cancer.

Fathy A, Allam A, ElHady AK, El-Gamil DS, Lin KC, Chang YH, Lee YH, Hilscher S, Schutkowski M, Ibrahim HS, Chen SH, Chen CH, Abadi AH, Sippl W, Chen PJ, Cheng YS, Abdel-Halim M
RSC medicinal chemistry 2025 Jun 18;16(6):2754-2784

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ANP32 proteins from ticks and vertebrates are key host factors for replication of Bourbon virus across species.

Zhang Z, Aziati ID, Nipper T, Boon ACM, Mehle A
Journal of virology 2025 Jun 17;99(6):e0052225

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Novel Visual Perspective for Tracking of Larval Development, Aging and Antiaging Drugs Screening by Fluorescent Sensing MsrA.

Zeng J, Yang T, Gao Y, Shen Y, Li S, Zhang H, Zhou J, Cheng D, He L
Analytical chemistry 2025 Jun 17;97(23):12060-12069

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Elacridar Inhibits BCRP Protein Activity in 2D and 3D Cell Culture Models of Ovarian Cancer and Re-Sensitizes Cells to Cytotoxic Drugs.

Stasiak P, Sopel J, Płóciennik A, Musielak O, Lipowicz JM, Rawłuszko-Wieczorek AA, Sterzyńska K, Korbecki J, Januchowski R
International journal of molecular sciences 2025 Jun 17;26(12)

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sPLA2-IIA modifies progranulin deficiency phenotypes in mouse models.

Yang C, Du H, Lee GB, Uematsu M, He W, Doré E, Yu W, Sanford EJ, Smolka MB, Boilard E, Baskin JM, Hao L, Hu F
Molecular neurodegeneration 2025 Jun 17;20(1):72

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RRP9 promotes prostate cancer metastasis and epithelial-mesenchymal transition through activation of the AKT/GSK3β/β-Catenin signaling pathway.

Da Z, Du Y, Chen Y, Da M, Zhou F
Discover oncology 2025 Jun 17;16(1):1129

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IDH1/MDH1 deacetylation activates the cGAS-STING pathway by promoting NETosis in acute liver failure.

Wang Y, Guo J, Zhang D, Zhang X, Luo K, Gong Z
International immunopharmacology 2025 Jun 17;158:114884

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Fast Lithium-Releasing Phosphate Glasses Promote the Resolution of Inflammation.

Abe GL, Xiao L, Sasaki JI, Sakai H, Kitagawa H, Kohno T, Funayama N, Imazato S
ACS applied bio materials 2025 Jun 16;8(6):4756-4765

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Ferulic acid identification in brown rice using untargeted metabolomics and network analysis and its effects in mitigating AFB1-induced hepatic damage.

Wang Q, Wang G, Wang Y, Fang X, Fu Y, Li G, Huang S, Ma Q, Zhao L
Food & function 2025 Jun 16;16(12):4970-4982

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Mechanism of berbamine-mediated DNA damage in synovial fibroblasts to alleviate rheumatoid arthritis.

Huang Y, Gong K, Tao M, Zhu Y, Li Y, Wang Y, Wu H, Hao W, Sun X
European journal of pharmacology 2025 Jun 15;997:177597

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Carbon monoxide gas molecules: Therapeutic mechanisms in radiation-induced lung injury.

Li Y, Zhou B, Liu D, Nie G, Yang F, Chen J, Cheng S, Kang Y, Liu B, Dong B, Liu M
Journal of colloid and interface science 2025 Jun 15;688:250-263

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Loss of ARNTL Enhances ER Stress and Apoptosis in CKD Through Disruption of NRF2 Signaling.

He L, Zhang Q, Sheng X, Yin J, Yan Y, Wu M, Bao H, Hu S, Wang N, Cao A
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 15;39(11):e70715

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TW-7 Alleviate Apoptosis of Embryos Derived From Vitrified MII Oocytes by Downregulation of JNK Signaling in Mice.

Wei Y, Qin J, Chen X, Fan X, Pan B, Ye J, Ning A, Du K, Zou S, Zang S, Yu G, Liang Q, Zhou G
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 15;39(11):e70712

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Inhibition of NR2F2 Attenuates Vascular Dysfunction in Diabetic Retinopathy by Alleviating Endoplasmic Reticulum Stress in Retinal Microvascular Endothelial Cells.

Zhang T, Yang Q, Chen J, Jiang J, Han J, Zhou Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 15;39(11):e70667

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Independent and synergistic effects of extreme heat and NO(2) pollution on diabetic nephropathy in a type II diabetes mouse model.

Qiao Z, Feng X, Sun W, Wang F, Lu C
Environmental pollution (Barking, Essex : 1987) 2025 Jun 15;375:126321

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The crosstalk between lung adenocarcinoma cells and M2 macrophages promotes cancer cell development via the SFRS1/miR-708-5p/PD-L1 axis.

Xu L, Li K, Li J, Xu F, Liang S, Kong Y, Chen B
Life sciences 2025 Jun 15;371:123599

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Different GJA8 missense variants reveal distinct pathogenic mechanisms in congenital cataract.

Li Z, Deng X, Cao Y, Xu H, Wang J, Yuan L, Deng H
Life sciences 2025 Jun 15;371:123596

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GDF15 promotes trophoblast invasion and pregnancy success via the BMPR1A/BMPR2/p-SMAD1 pathway: Implications for recurrent miscarriage.

Yang SH, Yang L, Shi Y, Xu HR, Gan J, Shi JX, Zhang Y, Shen SL, Wang J, Zhang X
Life sciences 2025 Jun 15;371:123586

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Sodium houttuyfonate prevents NiO-NPs induced lung injury in rats through the TNF-α/JAK-STAT signaling pathway.

Yang Z, Sun T, Zhang M, Li X, Wang Y, Li W, Wang Q, Wang X, Liu S, Wang W, Wang P
Ecotoxicology and environmental safety 2025 Jun 15;298:118306

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An all-silk-based functional system promotes tendon regeneration by regulating the cell fate of TSPCs in an inflammatory microenvironment.

Mo Q, Zheng H, Liu C, Sun Y, Cao Z, Sheng R, Zhang Y, Wang M, Kuang B, Backman LJ, Li J, Zhang W, Chen J
Acta biomaterialia 2025 Jun 15;200:432-451

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Sirt5-mediated polarization and metabolic reprogramming of macrophage sustain brain function following ischemic stroke.

Zhang L, Lv T, Hou P, Jin Y, Jia F
Brain research 2025 Jun 15;1857:149613

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Regulator of chromosome condensation 1 promotes hepatocellular carcinoma proliferation via cell-division-cycle-associated-8 dependent phosphoinositide 3-kinase/protein kinase B signaling.

Wang YT, Yong YL, Liu ZK, Shen YX, Yang XM, Chen ZN
World journal of gastrointestinal oncology 2025 Jun 15;17(6):106080

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Charged multivesicular body protein 7 was identified as a prognostic biomarker correlated with metastasis in colorectal cancer.

Wei JR, Ouyang YN, Tang MT, Yuan JZ, Wang PL, Jiang LH, Wu LC
World journal of gastrointestinal oncology 2025 Jun 15;17(6):105967

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Unlocking the potential of novel tetrahydro-β-carboline-based HDAC6 inhibitors for colorectal cancer therapy: Design, synthesis and biological evaluation.

Hemida N, El-Gamil DS, ElHady AK, Lin KC, Chang YH, Hilscher S, Schutkowski M, Ibrahim HS, Hamed MM, Chen SH, Chen CH, Abadi AH, Sippl W, Chen PJ, Cheng YS, Abdel-Halim M
Bioorganic chemistry 2025 Jun 15;160:108454

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2β-methoxy-2-deethoxyphantomolin synergistically enhances epirubicin effect against triple-negative breast cancer via targeted inhibition of AKT and HR pathways.

Gu J, You R, Zhao N, Xu X, Zhou J, Zhang X, Zhang Q, Jiang J, Jiang Y, Wen S
Bioorganic chemistry 2025 Jun 15;160:108453

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The development of pyridazinone-based andrographolide derivatives as anti-cancer agents with the ability of inhibiting the TFAP4/Wnt/β-catenin signaling pathway.

Zhang H, Xu Z, Xu Z, Bian S, Qiao N, Wang X, Zhang M, Guo F, Cui Y, Zheng F, Liu J, Wu D, Xu H
Bioorganic chemistry 2025 Jun 15;160:108440

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ANXA1 inhibits trophoblast ferroptosis in preeclampsia by downregulating KISS1†.

Rao Y, Tan S, Wang J, Jia J, Cai Z, Wu C, Wu P, Wang Z
Biology of reproduction 2025 Jun 15;112(6):1256-1272

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HNF4A promotes tumor progression in gastric cancer by transcriptional activation of KIF2C.

Lu H, Gan JH, Zhou LQ, Yuan YW, Zhou Q, Xin L
Clinical and experimental medicine 2025 Jun 14;25(1):205

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Integrating network analysis and experimental validation to reveal the ferroptosis-associated mechanism of velvet antler in the treatment of chronic atrophic gastritis.

Liao Q, Guo Z, Ding C, Zuo R, Liu G
Journal of food and drug analysis 2025 Jun 13;33(2):119-131

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Glutamate activates the MAPK pathway by inhibiting LPAR1 expression and promotes anlotinib resistance in thyroid cancer.

Liu B, Peng Y, Su Y, Diao C, Cha L, Cheng R
Discover oncology 2025 Jun 13;16(1):1082

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Rational Design of Novel Quinazolinone-Pyrrolodihydropyrrolone Analogs as PIM/HDAC Dual-Target Inhibitors for the Treatment of Acute Myelocytic Leukemia.

Xin Y, Xiao C, Wang N, Wu H, Kang W, Chen X, Liu C, You Q, Jiang Z, Guo X
Journal of medicinal chemistry 2025 Jun 12;68(11):11062-11080

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Podophyllum hexandrum Royle mitigates perimenopausal symptoms in an OVX rat model by activating the PI3K/AKT/mTOR pathway and enhancing estrogen receptor expression.

Tan CC, Cao SJ, Chao WH, Zhang B, Deng XY, Wang LN, Kang N, Qiu F
Journal of ethnopharmacology 2025 Jun 12;349:119968

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Guyuan Jiannao decoction improves neurovascular unit dysfunction by regulating PI3K/AKT/NF-κB signaling pathway in cerebral small vessel disease rats.

Zhong Z, Long H, Li N, Liu T, Wu M, Wang J, Liu M, Zhang X, Mei Z, Fang R, Ge J, Meng P
Journal of ethnopharmacology 2025 Jun 12;349:119942

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Ginsenoside Rg1 targets TLR2 to inhibit the NF-κB signaling pathway and ameliorate hematopoietic support of mesenchymal stromal cells.

Wei H, Liu Y, Huang C, Wang C, Jiang H, Wang L, Wang Y, Wang Z
Journal of ethnopharmacology 2025 Jun 12;349:119917

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Comprehensive multi-omics analysis of histone acetylation modulators identifies ASH1L as a novel aggressive marker for osteosarcoma.

Ni C, Sun Q, Yin H
Discover oncology 2025 Jun 12;16(1):1070

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Anti-Inflammatory Effect of Pestalotic Acid A Derived from Pestalotiopsis vismiae, an Endophytic Fungus of Ilex prenatal, in Lipopolysaccharide-Stimulated RAW264.7 Cells.

Hwang DY, Ki DW, Choi DC, Yun BS, Kim YH
Biomedicines 2025 Jun 12;13(6)

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A Dual-Factor Scaffold for Spinal Cord Injury Repair Targeting Inflammation and Ferroptosis.

Zou X, Zhu Y, Shu H, Su X, Xiong J, Ye W, Tang P, Wang H, Gao Y, Song T, Zou Z, Cai W
ACS applied materials & interfaces 2025 Jun 11;17(23):33540-33554

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Metabolomic and Proteomic Analyses Unveil That Polyethylene Glycol-Polycaprolactone-Loaded Curcumin Nanoparticles Induce Mitochondrial Dysfunction and Metabolic Reprogramming to Suppress Melanoma Growth.

Zhang Y, Zhou X, Zheng W, Chen J, Xu Q, Liang Z, Zhang H, Lin J, Xie W, Zhuo Y, Chen M, Zou F, Wen B, Tan Z, Zhong W, Yang H, Yang R
ACS applied materials & interfaces 2025 Jun 11;17(23):33422-33438

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Aberrant Development of Hippocampal GABAergic Neurons Arising from Hypothyroidism Contributes to Memory Deficits in Mice Through Maf Suppressing Mef2c.

Wu M, Zeng X, Cai Y, Chen H, Yang H
Biomedicines 2025 Jun 11;13(6)

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RUNX2 isoform II protects cancer cells from ferroptosis and apoptosis by promoting PRDX2 expression in oral squamous cell carcinoma.

Huang J, Jia R, Guo J
eLife 2025 Jun 11;13

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Targeting CIDEB alleviates liver steatosis and fibrosis in mouse MASH models.

Lin Y, Fan F, Mo Z, Huang Z, Zhou M, Ma Y, Qian C, Wang Y, Qian C, Liu X
Molecular therapy. Nucleic acids 2025 Jun 10;36(2):102567

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RNA polymerase II subunit 5-mediating protein limits TLR4-induced innate immune activation in macrophages by inhibiting IKKβ/NF-κB signaling during sepsis.

Pang SJ, Jiang TY, Wang NG, Cui XW, Wang H, Pan YF, Yang N, Dong LW
Cell communication and signaling : CCS 2025 Jun 10;23(1):274

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Mesenchymal Stem Cell-Derived Mitochondrial Transfer Promotes Tip Cell Phenotype via Glutathione Metabolic Reprogramming in Stroke Mice.

Zhang Q, Huang J, Chen X, Li L, Chen L, Zhou X, Zhao X, Liu M, Zhao W, Yan J, Wang Y, Su Y, Liu Y, Xu S, Zeng W
ACS nano 2025 Jun 10;19(22):20452-20471

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Molecular mechanism of rapamycin-induced autophagy activation to attenuate smoking-induced COPD.

Wang L, Jia J, Yu X, Luo M, Li J, Khan GJ, He C, Duan H, Zhai K
Biochemical and biophysical research communications 2025 Jun 1;764:151819

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BTN3A2 interacted with MFGE8 to alleviate preeclampsia by promoting ferroptosis and inhibiting angiogenesis.

Yuan X, Wang Q, Hu C, Yong W, Li P
Life sciences 2025 Jun 1;370:123584

---

BRD9 promotes the malignant phenotype of thyroid cancer by activating the MAPK/ERK pathway.

Deng Y, Li Y, Cao H
Anti-cancer drugs 2025 Jun 1;36(5):359-373

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Characterization of the recombination activity in the pituitary and ovary of Prop1-iCre knockin mice.

Zhao JM, Han Q, Chen C, Yan X, Yu S, Ma XH, Wei CC, Zhang WJ, Cao D
American journal of physiology. Endocrinology and metabolism 2025 Jun 1;328(6):E994-E1000

---

RGD peptide hydrogel downregulates mechanosignal YAP to inhibit postoperative scarring.

Lv Y, Liang L, Qin M, Jiang RP, Zong FF, Wu X, Wu KL, Liang L
Acta biomaterialia 2025 Jun 1;199:132-141

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Cyclophilin D knockdown/knockout promotes microglia M2 polarization by inhibiting STAT1 to alleviate neuroinflammation in neonatal white matter injury.

Zhou J, Gao T, Tang W, Wang Z, Zhao L, Wang L
Brain research 2025 Jun 1;1856:149596

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Prodigiosin inhibits proliferation and induces apoptosis through influencing amino acid metabolism in multiple myeloma.

Wang B, Shi R, Du W, Guo J, He N, Zhu Y, Yu H, Lu H, Zhong L, Li X, Zhou W, Yang F, Feng X
Bioorganic chemistry 2025 Jun 1;159:108349

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H 2 protects H9c2 cells from hypoxia/reoxygenation injury by inhibiting the Wnt/CX3CR1 signaling pathway.

Wang J, Ma B, Jiang X, Li C, Lin Z, Wang Y, Shi J, Wang G, Cui C
Medical gas research 2025 Jun 1;15(2):339-347

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KLF10 Induced by Hypothermic Machine Perfusion Alleviates Renal Inflammation Through BIRC2 /Noncanonical NF-κB Pathway.

Hu Q, Chen H, Lan J, Chen Y, Liu Z, Xiong Y, Zhou W, Zhong Z, Ye Q
Transplantation 2025 Jun 1;109(6):e273-e286

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Muscle-derived factor alleviated cognitive impairment caused by intestinal ischemia-reperfusion.

Tan Y, Mu G, Wang F, Fan X, Yang C, Shi Z, Bai Y, Xie B, Yu X, Feng J, Jia J, Wang X, Chen Y, Zhou J
Redox biology 2025 Jul;84:103682

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MOTS-c attenuates lung ischemia-reperfusion injury via MYH9-Dependent nuclear translocation and transcriptional activation of antioxidant genes.

Li X, Zhan F, Qiu G, Lu P, Shen Z, Qi Y, Wu M, Chu M, Feng J, Wen Z, Yao X, Wang A, Jin W, Zhang X, Liao J, Zhang J, Song M, Wang W, Wang X
Redox biology 2025 Jul;84:103681

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PINK1 Loss of Function Selectively Alters the Mitochondrial-Derived Vesicle Pathway.

Collier CL, Ruedi C, Thorne NJ, Tumbarello DA
FASEB bioAdvances 2025 Jul;7(7):e70030

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Fibroblast lipid metabolism through ACSL4 regulates epithelial sensitivity to ferroptosis in IBD.

Huang W, Zhang Y, Das NK, Solanki S, Jain C, El-Derany MO, Koo I, Bell HN, Aabed N, Singhal R, Castillo C, Buscher K, Ying Y, Dimitroff J, Sharma A, Shi J, Hogan SP, Dame MK, Higgins PDR, Colacino JA, Oh TG, Spence JR, Patterson AD, Greenberg AS, Greenson JK, Nusrat A, Shah YM
Nature metabolism 2025 Jul;7(7):1358-1374

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Glutathione-protected Au(22) Nanoclusters Ameliorates Hypoxic-Ischemic Brain Damage in Neonatal Rats via Sirt3/SOD2 Signaling Pathway.

Zheng Y, Feng X, Hu X, Zhu T, Ding J, Mao N, Xu H, Lou J, Yuan J, Wang X, Lin Z, Lin Z, Zhu J
Molecular neurobiology 2025 Jul;62(7):9469-9482

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Empagliflozin Inhibits Neuronal Ferroptosis Induced by Oxygen-Glucose Deprivation/Reoxygenation by Activating the Nrf2/HO-1 Pathway.

Ma J, Wang H, Jia J, Tao T, Shan L, Sun S, Wang M
Molecular neurobiology 2025 Jul;62(7):8768-8781

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RIOK1 phase separation restricts PTEN translation via stress granules activating tumor growth in hepatocellular carcinoma.

Meng F, Li H, Huang Y, Wang C, Liu Y, Zhang C, Chen D, Zeng T, Zhang S, Li Y, Zhang B, Lang C, Xia J, Xiong W, Pan S, Sun X, Thorne RF, Liu Y, Wang J, Zhang S, Song R, Wang J, Liu L
Nature cancer 2025 Jul;6(7):1223-1241

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Testis-Specific PDHA2 Is Required for Proper Meiotic Recombination and Chromosome Organisation During Spermatogenesis.

Wang G, Fang K, Shang Y, Zhou X, Shao Q, Li S, Wang P, Chen CD, Zhang L, Wang S
Cell proliferation 2025 Jul;58(7):e70003

---

LMO2 confers value as a potential immunotherapy marker in pan-cancer analysis and inhibits progression of Clear Cell Renal Cell Carcinoma.

Wang H, Wang C, Wei J, Zhao X, Yang X, Li R, Li M, Zhu Z
Translational oncology 2025 Jul;57:102409

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RNA‑binding protein MBNL1 regulates tumor growth, chemosensitivity and antitumor immunity in lung adenocarcinoma by controlling the expression of tumor suppressor RNF125.

Yan Y, Kong X, Jin X, Bu J, Ni B, Rao Z, Guo J, Xu S
Oncology reports 2025 Jul;54(1)

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DEPP1: A prognostic biomarker linked to stroma‑rich and immunosuppressive microenvironment, promoting oxaliplatin resistance in gastric cancer.

Qiu X, Pan T, Kuang T, Shen Y, Zheng Y, Geng H, Ni B, Xia X, Zhu C, Zhang Z, Cao H, Tu L
Oncology reports 2025 Jul;54(1)

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Inhibiting the REV-ERBα expression protects against mechanical overloading-induced cartilage clock disruption and osteoarthritis progression.

Xu X, Wang D, Ni B, Xu H, Wu Z, He T, Zhang Y, Hao X, Ding G, Zhang X, Meng QJ, Yang L
Journal of orthopaedic translation 2025 Jul;53:112-125

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Identification of the dysregulated let-7c-Sox2 network in the facial prominences of mouse embryos with early retinoid acid exposure.

Song C, Lu J, Wang Y, Zou Y
Developmental biology 2025 Jul;523:9-19

---

The Polarization of Macrophages Regulated by KCNG3 via the Activation of ASK1 Mediated by Potassium Ion Efflux.

Zhang S, Xin Y, Yang Y, Zhang Y, Geng J
Cell biology international 2025 Jul;49(7):810-823

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IL-17C-Mediated Upregulation of SMURF2 Induces Psoriatic Changes in Keratinocytes by Facilitating PPP6C Ubiquitination.

Mao J, Ma X, Sun Y, Wang W, Li B
Cell biology international 2025 Jul;49(7):798-809

---

High glucose facilitates hepatocellular carcinoma cell proliferation and invasion via WTAP-mediated HK2 mRNA stability.

Niu Y, Jia S, Xiao X, Tu K, Liu Q
Molecular and cellular biochemistry 2025 Jul;480(7):4149-4168

---

Inhibition of CDC27 O-GlcNAcylation coordinates the antitumor efficacy in multiple myeloma through the autophagy-lysosome pathway.

Wu HQ, Qin RC, Li WJ, Liu JN, Deng C, Zheng ZH, Zheng JP, Liu Y, Meng YF, Tang C, Tan HM, Duan FF, Tang Y, Xiao F, Lu LW, Dai XY, Ma KY
Acta pharmacologica Sinica 2025 Jul;46(7):2041-2055

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Blocking TSP1 Ameliorates Diabetes Mellitus-Induced Erectile Dysfunction by Inhibiting the TGF-β/SMAD Pathway.

Xia M, Yuan Y, Fang D, Tan X, Zhao F, Li X, Gao P, Zhou Z, Nan T, Xin Z, Li X, Guan R
The world journal of men's health 2025 Jul;43(3):580-594

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Thioredoxin-1 Downregulation in the SNpc Exacerbates the Cognitive Impairment Induced by MPTP.

Zhang X, Yan F, He XJ, Chen Y, Gu R, Dong X, Wei Y, Bai L, Bai J
Antioxidants & redox signaling 2025 Jul;43(1-3):138-150

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Advanced N-glycoproteomics and proteomics approach revealed sexually dimorphic molecular signatures in primary mouse hepatocyte.

Yang Q, Zhang Y, Zhang H, Yang Z, Feng Y, Ye B, Gong P, Qian G, Li D
Analytical and bioanalytical chemistry 2025 Jul;417(17):3893-3908

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Arsenic enhances endoplasmic reticulum stress via YTHDC1/AKR1C3 aix to promote the malignant transformation of human urothelial cells.

Chen C, Tong M, Chang Y, Li X, Wang J, Chen L, Huang C, Huang H, Zhao L
Toxicology letters 2025 Jul;410:199-210

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Leonurine protects against cisplatin-induced ototoxicity through its anti-oxidation and anti-apoptosis properties.

Zeng Z, Han L, Dong D, Tang H, Gao Z, Hu S, Zhu B, Zhang S, Shu Y, Yu Y
Toxicology letters 2025 Jul;410:1-15

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Integration of Machine Learning Algorithms and Single-Cell Sequencing Analysis Reveals the Efferocytosis-Related Molecular Subtype and Prognostic Scoring Index in Colon Adenocarcinoma.

Ju K, Liu X, Wang Q, Liu X, Li D, Tan B
Journal of gastroenterology and hepatology 2025 Jul;40(7):1772-1785

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NLRP3 Deficiency in Macrophages Ameliorates Gut Inflammation and Augments Treg Population In Vivo and In Vitro.

Zhu S, Shi P, Li H, Liang J, Xu M, Li Z, Zeng L, Xu K
Journal of biochemical and molecular toxicology 2025 Jul;39(7):e70382

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ZNF451 collaborates with RNF8 to regulate RNF168 localization and amplify ubiquitination signaling to promote DNA damage repair and regulate radiosensitivity.

Xu F, Xia Q, Chen B, Wang R, Zhang J, Zhao X, Zhang Z, Yao Z, Zhang J, Zhou S, Li X, Chen B, Xu A, Wu L, Zhao G
Cell death and differentiation 2025 Jul;32(7):1303-1316

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Metabolic reprogramming in astrocytes prevents neuronal death through a UCHL1/PFKFB3/H4K8la positive feedback loop.

Xiong J, Ge X, Pan D, Zhu Y, Zhou Y, Gao Y, Wang H, Wang X, Gu Y, Ye W, Teng H, Zhou X, Wang Z, Liu W, Cai W
Cell death and differentiation 2025 Jul;32(7):1214-1230

---

Carrier-free Nanotherapeutics unleashed: Ce6/siPD-L1 co-delivery system synergizes photodynamic and RNAi therapies to combat breast cancer.

Luo Y, Wang X, Li Y, Duan D, Liu K, Lei M, Zhang L, Zhu Y
International journal of biological macromolecules 2025 Jul;318(Pt 1):144962

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Methacrylated sericin/methacrylated hyaluronic acid composite microneedles with exosomes for diabetic wound healing.

Xu X, Shen Y, Wu J, Hong F, Xia H, Chen X, Lin G, Liu L, Xu RA
International journal of biological macromolecules 2025 Jul;318(Pt 1):144957

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Transcranial iTBS Combined With Trans-Spinal iTBS Targeting PDE1A/cAMP/PKA Axis Regulates Neural Regeneration After Spinal Cord Injury.

Fu Y, Wang X, Chen X, Wu S
CNS neuroscience & therapeutics 2025 Jul;31(7):e70525

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AD16 Modulates Microglial Activation and Polarization to Mitigate Neuroinflammation in Ischemic Stroke Models Through α7nAChR-ERK-STAT3 Signaling.

Zhao GJ, Zhang LM, Wang SR, Yang M, Jiang JH, Yuan BX, Huang C, Huang ZH, Tang XL, Chen T
CNS neuroscience & therapeutics 2025 Jul;31(7):e70519

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Ginsenoside Rb1 Alleviated the AKI to CKD Transition by Targeting VEGFR2.

Zhang K, Ji Y, Fu Z, Wang X, Zhang Y, Yang Y, Liu R, Chen X, Cai G, Hong Q
Journal of cellular and molecular medicine 2025 Jul;29(14):e70732

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Exploration of the Potential Bioactive Compounds and Functional Mechanism of Chaihu Sanshen Capsule in Ameliorating Myocardial Ischaemia-Reperfusion Injury: A Serum Pharmaco-Chemistry With Network Pharmacology Analysis.

Wang W, Zhang Z, Liu R, Zheng Y, Hu Y, Li X, Shen Z, Yuan H, Liu J
Journal of cellular and molecular medicine 2025 Jul;29(14):e70666

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Inflammation and IL-4 regulate Parkinson's and Crohn's disease associated kinase LRRK2.

Dikovskaya D, Pemberton R, Taylor M, Tasegian A, Bhattacharya P, Zeneviciute K, Sammler EM, Howden AJM, Alessi DR, Swamy M
EMBO reports 2025 Jul;26(13):3327-3356

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Fluorometholone inhibits corneal epithelial proliferation, migration via targeting Rho GTPases: RhoA, Rac1, and Cdc42.

Lin Y, Xu T, Jiang Q, Chen J, Zhang H, Reinach PS, Yan D, Qu J, Chen S
Experimental eye research 2025 Jul;256:110397

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Coriander-Derived Exosome-Like Nanovesicles Laden Hydrogel with Antioxidant Property Accelerates Wound Healing.

Wang T, Li Y, Hao L, Liu Y, Liu D, Zhang C, Yi H, Zhang J
Macromolecular bioscience 2025 Jul;25(7):e2400640

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Aquaporin-4-Mediated Water Permeability Rescues Aquaporin-3 Deficiency Caused Nephrogenic Diabetes Insipidus.

Ying Y, Qiu Z, Liu J, Quan Y, An Y, Lu F, Wang K, Li M, Zhou H, Yang B
Acta physiologica (Oxford, England) 2025 Jul;241(7):e70072

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Aerobic Exercise Restores Hippocampal Neurogenesis and Cognitive Function by Decreasing Microglia Inflammasome Formation Through Irisin/NLRP3 Pathway.

Zhao R, Tian X, Xu H, Wang Y, Lin J, Wang B
Aging cell 2025 Jul;24(7):e70061

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457 nm LED blue light inhibits oral squamous cell carcinoma cell proliferation via the PI3K/AKT pathway and autophagy.

Jiang H, Yang J, Fu Q, Qin H, Liu M
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2025 Jul;24(7):1079-1092

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LncRNA HCG11 regulates selinexor sensitivity in multiple myeloma.

Zhang Y, Wang X, Luo H, Liu X, Huang J, Mi Z, He S, Wen J, Gao Q, Yang H, Feng Y, Li L, Zhai X, Wang F, Dai Y, Zhang L, Niu T, Sun C, Zheng Y
Biochemical pharmacology 2025 Jul;237:116948

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Discovery of a novel BCL-2 inhibitor GW806742X for the treatment of TNBC.

Liu W, Xu J, Chen L, Zhang D, Zhang J, Lu L, Zhang X, Huang X, Zhang G
Biochemical pharmacology 2025 Jul;237:116925

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Phellodendrine chloride alleviates gouty arthritis through IL-6/STAT3 signaling pathway.

Qin YY, Qin ZY, Liang T, Qin DE, Hua SY, Tan MH, Guo S, Yang F, Shi L, Yu Y, Zhang GJ
Immunobiology 2025 Jul;230(4):152918

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Notch signaling pathway regulates the progression of fetal growth restriction through mediating immune dysfunction.

Ye L, Zheng X, Yang Y, Lyu Y
Biomedical reports 2025 Jul;23(1):111

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Hosta plantaginea Flower Ameliorates Chronic Pharyngitis by Suppressing Inflammation via the JAK-STAT/PI3K/MAPK Signaling Axis in Rats.

Li X, Wang J, Liang J, He J, Cao L, Yang L
Chemistry & biodiversity 2025 Jul;22(7):e202403254

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Sexual dimorphism of lung immune-regulatory units imprint biased pulmonary fibrosis.

Xiang P, Wang L, Feng X, Guo Q, Xie G, Sheng L, Chen L, Teng J, Yang J, Wu X, Peng X, Lu R, Luo X, Wen J, Zhou HY
Cellular & molecular immunology 2025 Jul;22(7):743-759

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Indole-3-propionic acid promotes Schwann cell proliferation following peripheral nerve injury by activating the PI3K/AKT pathway.

Zhang H, Wang S, Zhang Q, Du X, Xu D, Wen J, Jin M, Liu J, Jin X, Wang M, Luo L, Li L
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2025 Jul;22(4):e00578

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SARS-CoV-2 encoded ORF3a interacts with YY1 to promote latent HCMV reactivation.

Xia S, Huo X, Liu N, Liu X, Wang T, Guo M, Zeng C, Wan P, Chen J
PLoS pathogens 2025 Jul;21(7):e1013344

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Visualizing bulk autophagy in vivo by tagging endogenous LC3B.

Gao X, Xiong Y, Ma H, Zhou H, Liu W, Sun Q
Autophagy 2025 Jul;21(7):1591-1607

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RETRACTED ARTICLE: Copper Exposure Destroys the Integrity of the Blood-Testis Barrier (BTB) Through p38 MAPK-Meditated Autophagy Pathways.

Deng H, Lou Y, He R, Deng J, Zhu Y, Wu X, Guo H
Biological trace element research 2025 Jul;203(7):3987

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Lutein attenuates rhabdomyolysis-induced acute kidney injury by inhibiting ACSL4-mediated ferroptosis.

Liu C, Fu Z, Zhou W, Chang X, Cui Y, Geng X, Hong Q, Lv Y, Zhou F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Jul;188:118222

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Anthraquinones of Cassiae Semen alleviate lipid accumulation in obesity by regulating brown adipose tissue and liver function.

Li Y, Wu R, Li X, Li J, Zhang Y, Huang Y, Fan G, Li X
Chinese herbal medicines 2025 Jul;17(3):488-499

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L-Kynurenine activates the AHR-PCSK9 pathway to mediate the lipid metabolic and ovarian dysfunction in polycystic ovary syndrome.

Wang Y, Wu Y, Jiang H, Li S, Li J, Wang C, Yang L, Zhou X, Yu J, Zhai J, Chen ZJ, Du Y
Metabolism: clinical and experimental 2025 Jul;168:156238

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The role of the PDGF-BB/PDGFR-β signaling pathway in microcirculatory disturbances and BBB destruction after experimental subarachnoid hemorrhage in mice.

Tan G, Wang J, Xing W, He Z
Microvascular research 2025 Jul;160:104816

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Nerol enhances lipid synthesis in human sebocytes via cannabinoid receptor-2-mediated MAPK signaling.

Zhao Q, Liu Z, Wang Y, Li T, Wang J, Li Y, Li C, Zhai C, Zouboulis CC, Ding X, Ju Q, Hu Z
Journal of pharmacological sciences 2025 Jul;158(3):219-230

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Cytoplasmic and nuclear NFATc3 cooperatively contributes to vascular smooth muscle cell dysfunction and drives aortic aneurysm and dissection.

Liu X, Zhao L, Liu D, Zhao L, Tuo Y, Peng Q, Huang F, Song Z, Niu C, He X, Xu Y, Wan J, Zhu P, Jian Z, Guo J, Liu Y, Lu J, Liang S, Zheng S
Acta pharmaceutica Sinica. B 2025 Jul;15(7):3663-3684

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The cardiac glycoside periplocymarin sensitizes gastric cancer to ferroptosis via the ATP1A1-Src-YAP/TAZ-TFRC axis.

Ke A, Yang W, Zhang W, Chen Y, Meng X, Liu J, Dai D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156804

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Geniposide via enema alleviates colitis by modulating intestinal flora and bile acid metabolites, inhibiting S100A8/S100A9/NF-κB, and promoting TGR5 inhibition of NLRP3 inflammasome.

Zheng BX, Yi Y, Wang XW, Li CY, Zhao Y, Tian JZ, Wang LM, Han JY, Pan C, Liu SY, Liu CY, Qin SS, Tang X, Liu MT, Liang AH
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156791

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Gouqi-derived Nanovesicles (GqDNVs) promoted MC3T3-E1 cells proliferation and improve fracture healing.

Xu S, Zhang Z, Zhou X, Liao Y, Peng Z, Meng Z, Nüssler AK, Ma L, Xia H, Liu L, Yang W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156755

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Integrated network pharmacology, metabolomics, and microbiome studies to reveal the therapeutic effects of Anacyclus pyrethrum in PD-MCI mice.

Tuersong T, Wu QF, Chen Y, Shan Li P, Yong YX, Shataer M, Shataer S, Ma LY, Yang XL
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156729

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Umbilical Cord-Mesenchymal Stromal Cell-Derived Extracellular Vesicles Target the Liver to Improve Neurovascular Health in Type 2 Diabetes With Non-Alcoholic Fatty Liver Disease.

Du M, Yang H, Niu J, Huang J, Wang L, Xi J, Meng P, Liu Z, Ma G, Li J, Liu X, Guo L, Hu M, Tian Z, Liu B, Liu W, Shetty AK, Wu S, Baskys A, Long Q
Journal of extracellular vesicles 2025 Jul;14(7):e70125

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Identification of a new micropeptide altKLF4 derived from KLF4 that influences myeloma chemotherapeutic sensitivity.

Yao R, Zeng Y, Zhang Y, Cao X, Mao J, Li W, Xu K, Liu L
Cellular signalling 2025 Jul;131:111767

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Rescuing fertility: Itaconic acid prevents ovarian damage through NRF2-mediated pyroptosis pathways in diminished ovarian reserve models.

Yang L, Mo W, Xin L, Zhang M, Chen K, Guo X, Zhang J, Yu B
Cellular signalling 2025 Jul;131:111766

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Single-cell RNA sequencing reveals B cell dynamics and osteoclast activation in Talaromycosis-related bone destruction.

Wei RF, Chen XY, Zhou JH, Zhang Y, Xie PY, Teng YL, Zong SH, Zeng GF
Cellular signalling 2025 Jul;131:111708

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Paeoniflorin-6'-O-benzene sulfonate inhibits keratinocyte proliferation by restoring GRK2-JAK1 colocalization in mouse model of psoriasis.

Tian T, Wei M, Guan Y, Rao L, Luo T, Han C, Wei W, Ma Y
Cellular signalling 2025 Jul;131:111706

---

OTUB1 promotes glioma progression by stabilizing TRAF4.

Liu H, Tan S, Li Z, Qi J, Tang X, Zhang J
Cellular signalling 2025 Jul;131:111704

---

Sex-dependent effects of heat exposure on the middle ear health in mice.

Li J, Fan W, Yuan X, Wan T, Qin L, Zhang L, Hou T, Liu C, Li R
Journal of thermal biology 2025 Jul;131:104198

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Lactate transporter MCT4 regulates the hub genes for lipid metabolism and inflammation to attenuate intracellular lipid accumulation in non-alcoholic fatty liver disease.

Gou Y, Li A, Dong X, Hao A, Li J, Xiang H, Rahaman S, He TC, Fan J
Genes & diseases 2025 Jul;12(4):101554

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The bidirectional effects of APPswe on the osteogenic differentiation of MSCs in bone homeostasis by regulating Notch signaling.

Wang N, Shen X, Huang H, Zhao R, Jiwa H, Li Z, Li P, Ye J, Zhou Q
Genes & diseases 2025 Jul;12(4):101317

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PHOSPHO1 Suppresses Ferroptosis in Retinal Pigment Epithelial Cells by Reducing the Levels of Phosphatidylethanolamine Molecular Species.

Chen Z, Zhu X, Lu MM, Ou Q, Wang X, Zhao Z, Shen Q, Wang Q, Wang Z, Xu JY, Jin C, Gao F, Wang J, Zhang J, Zhang J, Jin X, Bi Y, Lu L, Xu GT, Tian H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(28):e2505359

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Intermediate Filament Protein BFSP1 Maintains Oocyte Asymmetric Division by Modulating Spindle Length.

Li Y, Zhang H, Zeng W, Miao Y, Sun S, Zhang Y, Xiong B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(28):e2504066

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Neuronal FGF13 Inhibits Mitochondria-Derived Damage Signals to Prevent Neuroinflammation and Neurodegeneration in a Mouse Model of Parkinson's Disease.

Song N, Wang X, Ha L, Hu L, Mei S, Liang Y, Zhao Y, Yang X, Zhang Q, Zhou Y, Ding J, Liu Y, Zhou Q, Han F, Hu G, Lu M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(28):e2503579

---

Isoquercitrin Alleviates Diabetic Nephropathy by Inhibiting STAT3 Phosphorylation and Dimerization.

Xuan C, Chen D, Zhang S, Li C, Fang Q, Chen D, Liu J, Jiang X, Zhang Y, Shen W, Cai G, Chen X, Li P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(25):e2414587

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Neuraminidase 1 Exacerbated Glycolytic Dysregulation and Cardiotoxicity by Destabilizing SIRT1 through Interactions with NRF2 and HIF1α.

Gao T, Tang Y, Zeng T, Wang J, Zhang X, Liu Q, Guan X, Tang X, Lu G, Li J, Liu M, Zhang D, Lv S, Gu J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(25):e2414504

---

WTAP-mediated m6A modification of ARG2 mRNA Inhibits Its expression and drives prostate cancer malignant progression.

Li J, Zheng Y, Chen C, Lin Z, Pan J, Jiang F, Zhong W
Mutation research 2025 Jul-Dec;831:111912

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LncRNA small nucleolar RNA host gene 1 (SNHG1) mediates acidic bile salt-induced EMT via the ULK1-Notch1 axis in Barrett's esophagus.

Zhou J, Zhao R, Li Z, Ma X, Jin W, Yuan Y, Li N, Liu B, Yang Y
Molecular biomedicine 2025 Jul 9;6(1):49

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A 14-bp motif in the KIT active promoter region is critical for melanin accumulation in yaks, mice, and humans.

Liu X, Wang T, Zheng Z, Dong C, Liu W, Niu Z, Yang Y, Wu X, Qiu Q, Yang Y, Li K, Lenstra JA, Yan P, Kang M, Li B, Fang L, Liu J
BMC biology 2025 Jul 9;23(1):208

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Low-intensity pulsed ultrasound as a strategy to boost exosome secretion by adipose-derived stem cells and uptake for myocardial infarction therapy.

Jiang R, Wang H, Zhong F, Hu Y, Liu J, Chen Y, Su W, Cao S, Deng Q, Zhou Q
Biomedical materials (Bristol, England) 2025 Jul 9;20(4)

---

Host protein ARF1 is a proviral factor for SARS-CoV-2 and a candidate broad-spectrum therapeutic target.

Zhang C, Min YQ, Xue H, Zhang H, Liu K, Tian Y, Yang Z, Zhao Z, Yang H, Shan C, Sun X, Ning YJ
Nature communications 2025 Jul 9;16(1):6326

---

Dermal papilla cells-conditioned medium attenuates oxidative stress-induced senescence via ferroptosis inhibition.

Ru Z, Wu Y, Qu Q, Miao Y, Zhu L, Hu Z
Scientific reports 2025 Jul 9;15(1):24789

---

GADD45G operates as a pathological sensor orchestrating reactive gliosis and neurodegeneration.

Shen T, Tai W, Jiang D, Ma S, Zhong X, Zou Y, Zhang CL
Neuron 2025 Jul 9;113(13):2176-2195.e10

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Juanbi Qianggu Formula inhibits fibroblast-like synovicytes activation via repressing LncRNA ITSN1-2 to promote RIP2 K48 ubiquitination.

Bian Y, Li F, A X, Xiang Z, Ma N, Wang J, Cao B, Xin P, Cheng X, Liu C, Xiang B, Shen J, Lu Q, Xiao L
Chinese medicine 2025 Jul 8;20(1):109

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bFGF-Mediated Inhibition of Astrocytes' Optogenetic Activation Impairs Neuronal Repair in Female Rats After Stroke.

Shao X, Yao Y, Shi V, Suo Q, Wu S, Wang H, Mamtilahun M, Li W, Tang Y, Yang GY, Xu Q, Zhang Z
International journal of molecular sciences 2025 Jul 7;26(13)

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Buyang Huanwu Decoction improves energy metabolism disorders after cerebral ischemia-reperfusion by regulating the SIRT1/AMPK signaling pathway to promote glycolysis and the tricarboxylic acid cycle.

Hu Z, Deng N, Li Y, Bai Y, Lan X, Xiong T, Ding H, Liu X, Deng C
Chinese medicine 2025 Jul 7;20(1):108

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Adipose-derived stem cells alleviate acute pancreatitis by inhibiting ferroptosis and oxidative damage in canines.

Ge Y, Chen M, Li M, Wang Z, Ding R, Wan Z, Xu E, Zheng J
Stem cell research & therapy 2025 Jul 7;16(1):355

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Mechanism of Brucea javanica against multiple myeloma via TNF-NF-κB signaling.

Wang Y, Zhang A, Chen Y, Qi D, Peng C, Liang Z, Guo J, Gu Y, Li H
Scientific reports 2025 Jul 7;15(1):24311

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Multi-omics study reveals gut microbiota dysbiosis and tryptophan metabolism alterations in GH-PitNET progression.

Liu J, Ye Z, Zhang Y, You S, Sun S, Lu L, Su W, Liu J, Pu J, Pan H, Zhu H, Deng K, Yao Y, Hu X, Zhang S
Scientific reports 2025 Jul 7;15(1):24261

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THEM6 modulates carboplatin sensitivity by regulating ferroptosis through FDFT1 in triple-negative breast cancer.

Zeng Y, Xu Z, Huang J, Yi Q, Chen X, Wang J, Du Z, Tian J, Yan Y
Breast cancer research : BCR 2025 Jul 6;27(1):124

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Design, synthesis, and biological evaluation of quinolinyl-ureido-phenyl-hydrazide derivatives and quinolinyl-hydrazide derivatives as anticancer agents targeting Nur77-mediated ferroptosis.

Gao YF, Yang YJ, Qin JB, Yu MY, Hu SW, Zhang HF, Lin FH, Hu HY, Fang MJ, Zeng JZ
European journal of medicinal chemistry 2025 Jul 5;291:117559

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Macrophage-mimetic liposomes co-delivering ceria and Ac2-26 peptide for penumbra protection in ischemic stroke.

Bai L, Li N, Li H, Dai Y, Bai Y, Ma F, Sha D, Xia S, Xu Y, Cao X
Journal of nanobiotechnology 2025 Jul 5;23(1):488

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FLT3 ligand regulates expansion of regulatory T-cells induced by regulatory dendritic cells isolated from gut-associated lymphoid tissues through the Notch pathway.

Li N, Mao J, Tang H, Tan X, Bi J, Wu H, Chen X, Wang Y
Chinese medical journal 2025 Jul 5;138(13):1595-1606

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The Identification of Proteolytic Substrates of Calpain-5 with N-Terminomics.

Gal J, Dufour A, Young D, Yang ES, Geddes JW
International journal of molecular sciences 2025 Jul 4;26(13)

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The Effects of Different Types of Exercise on Pulmonary Inflammation and Fibrosis in Mice with Type 2 Diabetes Mellitus.

Gao H, Ma X, Wang Z, Zhu D, Guo Y, Zhao L, Xiao W
Cells 2025 Jul 4;14(13)

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Treatment targets of cellular senescence and circadian rhythms in ischemic stroke.

Zeng F, Wang M, He M, Li Z, Zhang Y
Medicine 2025 Jul 4;104(27):e43220

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Aldehyde Oxidase 1 Deficiency Enhances Aerobic Exercise Performance by Promoting Skeletal Muscle Adaptation and Improving Mitochondrial Function.

Liu Y, Wang QQ, Huang TE, Yao M, Wang BH, Huang CP, Wang S, Lu YF, Lan XQ, Tian XL, Xiang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 31;39(14):e70815

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LMOD2 interaction with ACTC1 regulates myogenic differentiation.

Wang K, Liu C, Yi L, Liufu S, Chen W, Liu X, Chen B, Xu X, Liu J, Liu X, Yin Y, Ma H
BMC genomics 2025 Jul 31;26(1):709

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Mechanisms of cell senescence and apoptosis in cyclophosphamide-induced premature ovarian failure in rats.

Wu J, Wei Y, Peng Q, Zhu J, Shi H, Zhao T, Yuan T
Journal of ovarian research 2025 Jul 31;18(1):172

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Sivelestat sodium: a novel therapeutic agent in a mouse model of acute exacerbation pulmonary fibrosis through multiple mechanisms.

Xie W, Chen X, Wang Q, Yan C, Liu Y, Zhang M, Sun Y, Yan X, Guo B, Chen B
Journal of thoracic disease 2025 Jul 31;17(7):5024-5043

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STAT1 and STAT6 orchestrate Cbs transcription and transsulfur metabolism in microglia and contribute to parkinson's disease-related neuroinflammation.

Liu Y, Wang Z, Ma YT, Chen YX, Qian XY, Hou XO, Wan B, Ren HG, Hu LF
Cellular and molecular life sciences : CMLS 2025 Jul 30;82(1):294

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NEFA Induces Ferroptosis in Transition Dairy Cattle Liver by Increasing Lipid Reactive Oxygen Species and Downregulating SLC7A11.

Zhu Y, Wang G, Feng D, Li S, Zhang X, Yao J, Deng L, Lei X
Journal of agricultural and food chemistry 2025 Jul 30;73(30):18733-18745

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Metabolomics and proteomics reveal blocking argininosuccinate synthetase 1 alleviates colitis in mice.

Liu S, Sun H, Du Z, Lu S, Wang C, Zhang Y, Luo Z, Wang L, Fan Z, Wei P, Yan Y, Zhang J, Yin S, Liu T, He Q, Guo X, Ding K, Zhou J, Hua H, Yu C, Xu W, Shan J, Li Y, Xu Y, Shen X, Cao G, Zhou W
Nature communications 2025 Jul 30;16(1):6983

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Dysregulation of adipocytokines via the hsa-miR-548ay-3p/PPARγ signaling pathway leads to cardiac fibrosis.

Chen Y, Fang C, Liu W, Lei K, Hu P, Tang CE, Wang L, Luo F
Scientific reports 2025 Jul 30;15(1):27779

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TC2N promotes the proliferation and invasion of head and neck cancer cells with the p53-R175H.

Zhang Q, Zhou X, Hao X, Sun Q, Zhang G, Xu S
Translational cancer research 2025 Jul 30;14(7):3905-3919

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BAG2 releases SAMD4B upon sensing of arginine deficiency to promote tumor cell survival.

Chen MY, Sun CY, Zhao R, Guan XL, Li ML, Zhang F, Wan ZH, Feng JX, Yin M, Lei QY, Ma QX
Molecular cell 2025 Jul 3;85(13):2581-2596.e6

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Rhein Inhibits Microglia-Mediated Neuroinflammation and Neuronal Damage of Alzheimer's Disease via Regulating the Glutamine-Aspartate-Arginine-NO Metabolic Pathway.

Chi B, Zhang Z, Zhang Z, Zhang H, Tian M, Wang Y, Gao X
International journal of molecular sciences 2025 Jul 3;26(13)

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Increased CDKN2A expression correlates with resistance to platinum-based therapy and decreased infiltration of B lymphocytes in colon adenocarcinoma.

Gu R, Li S, Yu B, Gu J, Guan B, Wu H
Functional & integrative genomics 2025 Jul 3;25(1):144

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Transcription factor TCF3 promotes bladder cancer development via TMBIM6-Ca(2+)-dependent ferroptosis.

Yang WF, Guo WM, Luo QT, Lu J, Tan ZK, Ye YC, Fan G
Cell death discovery 2025 Jul 3;11(1):303

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Physical and functional interaction of Lrrc56 and Odad3 controls deployment of axonemal dyneins in vertebrate multiciliated cells.

Reyes-Nava NG, Lee C, Papoulas O, Hong J, Marcotte EM, Wallingford JB
bioRxiv : the preprint server for biology 2025 Jul 3;

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Endoplasmic reticulum-mitochondria coupling prompts ZBP1-mediated RPE cell PANoptosis in age-related macular degeneration.

Zhang A, Wei TT, Yin H, Tan CY, Han C, Yao Y, Zhu L
Communications biology 2025 Jul 29;8(1):1118

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Salvianolic Acid B Attenuates Liver Fibrosis via Suppression of Glycolysis-Dependent m1 Macrophage Polarization.

Song H, Li ZW, Xu W, Tan Y, Kuang M, Pei G, Wang ZQ
Current issues in molecular biology 2025 Jul 29;47(8)

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SLC4A11 is a targetable marker correlated with therapeutic responses in ovarian cancer.

Li X, Yuan J, Wang F, Guan B, Guan W, Shi J, Lu Q, Zhang J, Xu G
Journal of ovarian research 2025 Jul 29;18(1):167

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Exercise Ameliorates Dopaminergic Neurodegeneration in Parkinson's Disease Mice by Suppressing Microglia-Regulated Neuroinflammation Through Irisin/AMPK/Sirt1 Pathway.

Wang B, Li N, Wang Y, Tian X, Lin J, Zhang X, Xu H, Sun Y, Zhao R
Biology 2025 Jul 29;14(8)

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Targeting EGR1-ATF3 signaling mitigates paravertebral muscle degeneration by regulating cell death and inflammaging.

Wang X, Wang Q, Wang Z, Zhou Y, Jiang X, Li Y
Biological research 2025 Jul 28;58(1):52

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Exosome-derived SLC12A2-DT promotes macrophage M2 polarization-mediated hepatocellular carcinoma progression.

Zhou J, Ma W, Zhou R, Ma D, Liu C, Wang F, Yuan L, Xu L, Wang C, Li Q
International immunopharmacology 2025 Jul 28;160:114955

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Guilu erxian glue improves sperm quality in oligasthenospermia mice by promoting TDRP methylation and regulating the cAMP/PKA pathway.

Zhu C, Li Y, Liu L, Xie J, Hu Z, He Q, Sheng W
Scientific reports 2025 Jul 28;15(1):27498

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SETDB1 knockdown boosts recombinant protein in CHO cells via epigenetic transcriptional silencing.

Lu JT, Zhang M, Gao YP, Yang LL, Cui ZM, Han MM, Zhang X, Xu HY, Wang XY, Qiu LL, Hua ZC, Wang TY, Jia YL
AMB Express 2025 Jul 26;15(1):110

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Pro-Inflammatory Microglia Exacerbate High-Altitude-Induced Cognitive Impairment by Driving Lipid Droplet Accumulation in Astrocytes.

Fan X, Cao S, Fang Y, Zhu L, Wang X
Antioxidants (Basel, Switzerland) 2025 Jul 26;14(8)

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Glucose Metabolism Sustains Aberrant STAT3 Signaling in Colorectal Cancer via Glycosylated Paracrine Factors.

Buscher K, Temprine K, Mays C, Aabed N, Kerk S, Bell HN, Nieto Carrion JA, Greenbaum H, Ponnusamy V, Ramakrishnan SK, Lyssiotis CA, Xue X, Shah YM
bioRxiv : the preprint server for biology 2025 Jul 26;

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Biallelic BRCA2 variants induce premature ovarian insufficiency by impaired meiotic homologous recombination.

Wu X, Zhang Q, Li C, Zhuang S, Liu H, Jiao X, Zhao S, Qin Y, Guo T
Communications biology 2025 Jul 25;8(1):1104

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Dysfunction of Autophagy in Adipose Tissue Macrophages Regulated via FoxO1 in Obesity-Related Severe Acute Pancreatitis.

Ling X, Zhang Z, Lin L, Guo X, Ding Z
International journal of molecular sciences 2025 Jul 25;26(15)

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UBE2C: a potential therapeutic target and prognostic biomarker for prostate cancer patients.

Li S, Liu Y, Wu X, Zhang Q, Yuan W
Functional & integrative genomics 2025 Jul 25;25(1):159

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MCAM interacts with integrin β1 to promote EGFR-TKI resistance in lung adenocarcinoma through the JAK3 signalling pathway.

Zhang S, Chen Y, Li C, Zhao J, Jiao M, Zhang M, Ma C, Wang A, Li J, Zeng Y, Zhu J, Mu C, Huang JA, Liu Z
Journal of translational medicine 2025 Jul 25;23(1):831

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Identifying fibroblast-derived sFRP2 as a therapeutic target and engineering siRNA therapy for uterine scarring.

Cheng J, Zhang S, Gui Q, Pu Z, Chen Z, Wei Q, Qi H, Zhang J
Nature communications 2025 Jul 25;16(1):6850

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Hypoxia-mediated HES4 promotes the proliferation and motility of hepatocellular carcinoma cell by enhancing COL4A2 transcription.

Zhao P, Xu H
Discover oncology 2025 Jul 25;16(1):1405

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Comparative Analysis of Testicular Transcriptional and Translational Landscapes in Yak and Cattle-Yak: Implications for Hybrid Male Sterility.

Cao M, Guo S, Ding Z, Hu L, Xiong L, Ge Q, Pei J, Guo X
Biomolecules 2025 Jul 25;15(8)

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Ponicidin triggered ferroptosis in esophageal squamous cell carcinoma by suppressing the SLC7A11/Glutathione/GPX4 signalling axis.

Liu W, Zhang J, Wu M, Ren D, Chen C, Du Z, Li Q, Chang J, Pu Q, Liu Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156925

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Unveiling XinJia-LuHuang Granules' protective mechanism against atherosclerosis: Integrating network pharmacology, metabolomics, and experimental validation.

Liu X, Liu L, Ren X, Chen Y, Yin M, Xie H, Sun T, Tan Y, Wang S, Xu D, Tang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156919

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Protocatechuic acid suppresses ferroptosis to protect against hypoxic-ischemic encephalopathy by targeting the HIF-1α/VEGFA axis.

Zhang X, Luo J, Bharati L, Hua Z, Chen S, Dong Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156900

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Kirenol alleviates cerebral ischemic injury by promoting synaptic plasticity via HDAC2-mediated BDNF expression.

Guo M, Ye Y, Li X, Luo S, Cai H, Hong X, Zhang X, Zhang Y, Xu W, Li H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156605

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Discovery of 2-Pyrazolylpyrimidinone Derivatives as New SPOP Inhibitors for Renal Cell Carcinoma Therapy.

Zhang Q, Zhou Y, Zhao J, Hu L, Zhu Z, Wang H, Jin Y, You Q, Jiang Z, Guo X
Journal of medicinal chemistry 2025 Jul 24;68(14):14945-14961

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Discovery of a Novel EGFR PROTAC Degrader against C797S Resistance Mutation with Potent Antitumor Efficacy in NSCLC Treatment.

Wang X, Wang C, Ma Y, Piao Y, Shi Y, Yang S, Li J, Fan Y
Journal of medicinal chemistry 2025 Jul 24;68(14):14569-14593

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Da-yuan-yin decoction alleviates bleomycin-induced pulmonary injury by inhibiting epithelial-mesenchymal transition via E-cadherin/β-catenin complex restoration.

Lin J, Wang S, Li Z, Li J, Wang X, Wan X, Li C, Chu F, Gai C, Li Y, Ding X, Li Y
Journal of ethnopharmacology 2025 Jul 24;351:120148

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Integrating network pharmacology and transcriptomics reveals that Bushen Huoxue recipe ameliorates ferroptosis and apoptosis in granulosa cells by regulating PI3K/Akt signaling pathway in premature ovarian insufficiency mice.

Huang Y, Zhu M, Zhang Z, Liu Z, Li F, Hu R, Geng Y, Song Y, Ma W, Dong H, Xu L, Zhang M, Song K
Journal of ethnopharmacology 2025 Jul 24;351:120057

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Kai-Xin-San ameliorates fluoxetine-resistant depressive-like behaviors by modulating tryptophan-kynurenine metabolic homeostasis in a rodent model.

Yao L, Jing R, Wang C, Wang Y, Li X, Wu X, Wang Y, Liu L, Mu L, Liu P, Hu Y
Journal of ethnopharmacology 2025 Jul 24;351:120011

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EphrinB2 alleviates tubulointerstitial fibrosis in diabetic kidney disease.

Ni L, Zhou Q, Gao X, Chen F, Yusufu A, Chen JH, Yuan C, Wu X
Journal of translational medicine 2025 Jul 24;23(1):821

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Internalized polystyrene nanoplastics trigger testicular damage and promote ferroptosis via CISD1 downregulation in mouse spermatocyte.

Lv J, Liu G, Wang Z, Zhang J, Li Y, Wang Y, Liu N, Altyn S, Jiang Z
Journal of nanobiotechnology 2025 Jul 24;23(1):537

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The A-C linker controls centriole structural integrity and duplication.

Bournonville L, Laporte MH, Borgers S, Guichard P, Hamel V
Nature communications 2025 Jul 24;16(1):6836

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Renal tubular GSDME protects cisplatin nephrotoxicity by impeding OGT-STAT3-S100A7A axis in male mice.

Chen Q, Sun P, Zhou J, Long T, Xiao A, Liu Z, Xu S, Lei W, Zhang R, Tian J, Zhou M, Hu Z, Zhu F, Nie J
Nature communications 2025 Jul 24;16(1):6807

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Preparation, Characterization, and Functional Evaluation of a Novel Recombinant Hypoglycemic Protein with Multifunctional Effects.

Liu T, Ma X, Duan Z
Journal of agricultural and food chemistry 2025 Jul 23;73(29):18366-18379

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Small intestinal γδ T17 cells promote SAE through STING/C1q-induced microglial synaptic pruning in male mice.

Wu Y, Zhang Y, Yu Y, Wang X, Zhen Z, Yuan Y, Xie B, Han M, Wang M, Zhang X, Sun X, Wen X, Hashimoto K, Shang Y, Yuan S, Zhang J
Nature communications 2025 Jul 23;16(1):6779

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CD317 functions as a key antiviral factor in human herpesvirus 6 (HHV-6) infection.

Xu X, Song M, Zhang X, Jia J, Chen S, Xie H, Li L, Ma J, Tang H
Journal of virology 2025 Jul 22;99(7):e0084125

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The catalytic efficiency of METTL16 affects cellular processes by governing the intracellular S-adenosylmethionine setpoint.

Flaherty JN, Sivasudhan E, Tegowski M, Xing Z, McGinnis MM, Hunter OV, Featherston KM, Sethia K, Tu BP, Meyer KD, Conrad NK
Cell reports 2025 Jul 22;44(7):115966

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Mitochondrial thermal proteome profiling reveals aberrant activation of pyruvate dehydrogenase upon cuproptosis.

Huang Z, Liu Y, Zeng Y, Wang J, Sun S, Heng Tan CS, Chen PR
Cell reports 2025 Jul 22;44(7):115937

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SUV39H1-dependent methyl-degron is a critical regulator of skeletal homeostasis.

Li Q, An H, Bai R, Sun Q, Yang R, Xin T, Zhuang Z, Lu Y, Tang Y, Chen G, Zhang W, Zhang Y, Han B
Cell reports 2025 Jul 22;44(7):115910

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A Multifaceted Nanodrug Disrupts the Copper-Iron Homeostasis to Enhance Cancer Radiotherapeutic Effect.

Hua Y, Cao S, Yu Y, Chu C, Yang L, Ge S, Wang Y, You Z, Yu J
ACS nano 2025 Jul 22;19(28):26091-26104

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Large-sized polystyrene microplastics induce oxidative stress in AML12 cells.

Zhao B, Liu R, Guo S, Li S, Huang Z, Wang Y, Yu C, Hou Z, Zhang Y, Zhang Y, Liu X
Scientific reports 2025 Jul 22;15(1):26616

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Growth hormone combined with estrogen improves intrauterine adhesion fibrosis by downregulating endometrial microbial citraconic acid to target β-catenin protein.

Zeng Y, Yang Y, Zeng F, Feng Q
mSystems 2025 Jul 22;10(7):e0169224

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Weissella cibaria suppresses colitis-associated colorectal cancer by modulating the gut microbiota-bile acid-FXR axis.

Hao Q, Huang F, Chang L, Dai H, Chen W, Yao Y, Zhen Y
mSystems 2025 Jul 22;10(7):e0028825

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Two Spag6 genes control sperm formation and male fertility in mice.

Liu Y, Li W, Li T, Zheng C, Niu C, Schmitt A, Yap YT, Abdulghani M, Yuan S, Melander C, Strauss JF 3rd, Toure A, Zhang L, Zhang Z
bioRxiv : the preprint server for biology 2025 Jul 22;

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Lactylation of LSD1 is an acquired epigenetic vulnerability of BRAFi/MEKi-resistant melanoma.

Li A, Gong Z, Long Y, Li Y, Liu C, Lu X, Li Q, He X, Lu H, Wu K, Nie Y, Tan J, Ye J, You H
Developmental cell 2025 Jul 21;60(14):1974-1990.e11

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HBV DNA integration gene CCDC91 is oncogenic and a potential therapeutic target for hepatocellular carcinoma.

Li M, Wu S, Luo H, Niu J, Fang Y, Chen W, Cao L, He Y
Communications biology 2025 Jul 20;8(1):1079

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Matrix stiffness regulates glucose-6-phosphate dehydrogenase expression to mediate sorafenib resistance in hepatocellular carcinoma through the ITGB1-PI3K/AKT pathway.

Ren R, Zhang S, Peng Z, Ji X, Song H, Wang Q, Sun X, Wang H, Dong Y
Cell death & disease 2025 Jul 20;16(1):538

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P4HA2 promotes the progression of papillary thyroid cancer by enhancing degradation of IκBα to activate NF-κB signaling pathway.

Li R, Zhao M, Sun M, Wu Y, Miao C, Fangyu L, Wu M, Shi X, Lu J, Yue X
Cancer cell international 2025 Jul 2;25(1):249

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Altered cofactor recruitment and nucleosome dynamics underlie bisphenol A's impact on ERα-mediated transcriptional bursting.

Day CR, Yaşar P, Adedoyin G, Bennett BD, Chow CC, Rodriguez J
iScience 2025 Jul 18;28(7):112864

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CircYAP1 inhibits osteosarcoma progression through the miR-135b-5p/FRK axis.

Du M, Zhang X, Cong M, Cai C, Zhang Q, Xin H, Yang L, Geng Q, Shang M, Zhang Z, Shen L, Tan S, Han K
iScience 2025 Jul 18;28(7):112858

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Benzyl isothiocyanate induces heart regeneration.

Sakaguchi A, Kawasaki M, Saito Y, Murata K, Masumoto H, Kimura W
iScience 2025 Jul 18;28(7):112724

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AF6 regulates intestinal IgA via crosstalk between intestinal epithelial cells and immune cells in inflammatory bowel disease.

Lu L, Xu K, Qu H, Song L, Song Y, Wu Y, Sun X, Kong J, Wen Q, Jiao J, Liu Z, Xia J, Zhan L
iScience 2025 Jul 18;28(7):112658

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Quantitative Proteomics Reveals the Role of Lysine Lactylation in Lenalidomide-Resistance in Multiple Myeloma Cells.

Guo X, Ren X, Yan C, Huang H
ACS chemical biology 2025 Jul 18;20(7):1728-1738

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hucMSC-derived exosomes targeting macrophage polarization attenuate systemic inflammation in T1DM via INS/SOD1 delivery.

Chen X, An H, Du Y, Zhong H, Zhang F, Zeng X, Lv F, Tian Z, Jiang Z, Peng Q, Li Z, Li S, Zhong B, Lu X, Zhu Y
Stem cell research & therapy 2025 Jul 18;16(1):384

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Identification of a disulfidptosis-correlated ferroptosis prognostic model in breast cancer.

Hu T, Shan BF, Xu JH, Zeng TX, Zhao L, Yu B
Medicine 2025 Jul 18;104(29):e42168

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Synthesis and biological evaluation of asiatic acid derivatives as c-Kit inhibitors.

Ma JJ, Zhang LF, Chen G, Liu LM, Wang Z, Meng YQ
Journal of Asian natural products research 2025 Jul 18;:1-19

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Site-resolved assessment of targeted protein degradation.

Moreno-Ballesteros R, Pembridge T, Beniwal G, Virdee S
Cell chemical biology 2025 Jul 17;32(7):969-981.e7

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The Upregulation of L1CAM by SVHRSP Mitigates Neuron Damage, Spontaneous Seizures, and Cognitive Dysfunction in a Kainic Acid-Induced Rat Model of Epilepsy.

Li Z, Ge B, Li H, Huang C, Ji Y, Schachner M, Yin S, Li S, Zhao J
Biomolecules 2025 Jul 17;15(7)

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Light-activated multimodal nanoplatform for enhanced synergistic therapy of breast cancer.

Liu Y, Gong S, Aldahmash W, Ashraf K, Li Z, Khan IM, Niazi S, Guo M, Mohsin A
Scientific reports 2025 Jul 17;15(1):25995

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Cell type-specific master metabolic regulators of Alzheimer's disease.

Qiu Y, Hou Y, Wetzel L, Caldwell JZK, Zhu X, Pieper AA, Liu T, Cheng F
bioRxiv : the preprint server for biology 2025 Jul 17;

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Chlorella pyrenoidosa Polysaccharide CPP-3a Promotes M1 Polarization of Macrophages via TLR4/2-MyD88-NF-κB/p38 MAPK Signaling Pathways.

Pi Y, Yuan Q, Qin S, Lan C, Nong Q, Yun C, Tang H, Leng J, Xiao J, Zhao L, Zhang L
Marine drugs 2025 Jul 16;23(7)

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LncRNA USP2-AS1 facilitates colorectal cancer development through the PHLDA2/PI3K/AKT axis.

Zhu J, Lin S, Chang L, Luo Q, Qian M, Ding J, Li J, Pu J, Wang K
Experimental cell research 2025 Jul 15;450(2):114649

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MSCs in acute kidney injury treatment: Modulating mitochondrial function and inhibiting pyroptosis via PGC-1α.

Wang Y, Ding Y, Dong H, Wuren T, Luo P
Experimental cell research 2025 Jul 15;450(2):114583

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AlkB Homolog 5 Regulates Hexokinase 2-Mediated Glycolysis and Participates in the Progression of Endometriosis.

Liu JJ, Fang YQ, Xiong WQ, Liu HW, Li JY, Wang XP, Wang HJ, Zhang L, Liu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 15;39(13):e70813

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m5C-modified circRREB1 promotes lung cancer progression by inducing mitophagy.

Cai D, Chen X, Xu H, Zhao Q, Zhou X, Wu J, Yuan S, Gao Y, Li D, Zhang R, Peng W, Li G, Nan A
Journal of experimental & clinical cancer research : CR 2025 Jul 14;44(1):203

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KMT2C deficiency drives transdifferentiation of double-negative prostate cancer and confer resistance to AR-targeted therapy.

Guo J, Li N, Liu Q, Hao Z, Zhu G, Wang X, Wang H, Pan Q, Xu B, Han Y, Zhang G, Lian Y, Zhang W, Gu Y, Lin N, Zeng X, Jin Z, Lan W, Jiang J, Gao D, Dong L, Yuan H, Liang C, Qin J
Cancer cell 2025 Jul 14;43(7):1261-1278.e10

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Sulforaphane-cysteine inhibits α-tubulin/PD-L1/PFKFB4 axis leading to apoptosis in human glioblastoma.

Li J, Wu D, Zhang S, Wu Y, Bi X, Zhou Y, Wu W
Medical oncology (Northwood, London, England) 2025 Jul 14;42(8):333

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Serotype-specific host proteome remodeling in human foreskin fibroblasts during lytic HSV-1 and HSV-2 infection.

Pan X, Xie J, Zhang Z, Guo X, Li J, Lin D, Qian Y, Xu J, Hu Y, Shi J
Virology journal 2025 Jul 14;22(1):239

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Subregion-specific suppression of dopamine D1 receptor expression prevents L-DOPA-induced dyskinesia in a mouse model of Parkinson's disease.

Sugiyama K, Kuroiwa M, Shuto T, Hwang S, Oh YS, Nishi A
Neuroscience letters 2025 Jul 13;859-861:138273

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5-Fluorouracil induces ferroptosis in breast cancer cells via targeting SLC7A11.

Ji G, Yuan W, Wang X, Li W, Sun Z, Wei Z, Zhou L, Hu H
Biochemical and biophysical research communications 2025 Jul 12;770:151972

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Critical Residues in the Gβ Subunit Mediate Selective Recruitment of the Gαq Heterotrimer to Activated G Protein-Coupled Receptors.

Yao Y, Wang D, Wang S, Ouyang X, Zhao L, Chen H, Xu J
ACS pharmacology & translational science 2025 Jul 11;8(7):2048-2060

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Immunogenicity evaluation of a recombinant pseudorabies virus co-expressing PCV2 and PCV3 capsid proteins in mice and piglets.

Li H, Zhang J, Guo R, Li J, Zhang X, Han L, Xie H, Wang X
Vaccine 2025 Jul 11;60:127307

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Kaempferol Alleviates Carbon Tetrachloride-Induced Liver Fibrosis in Mice by Regulating Intestinal Short-Chain Fatty Acids.

Zhang S, Tang F, Zhou Z, Li L, Tang Y, Fu K, Tan Y, Li L
International journal of molecular sciences 2025 Jul 11;26(14)

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Apoptotic extracellular vesicles derived from human dental pulp stem cells facilitate periodontal tissue regeneration.

Xia J, Zhang Z, Weng J, Zhu G, Xu Z, Zeng L, Pathak JL, Yu L
BMC oral health 2025 Jul 11;25(1):1150

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A novel 1,8-naphthalimide-piperazine-amidobenzenesulfonamide derivative targets carbonic anhydrase IX to induce ferroptosis, apoptosis and autophagy in colorectal cancer cells.

Zhou XQ, Huang YX, Liang QL, Huang RZ, Zhang Y, Lu HR, Ma XL, Ariffin NS
RSC medicinal chemistry 2025 Jul 11;16(9):4427-39

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USP5-Mediated PD-L1 deubiquitination regulates immunotherapy efficacy in melanoma.

Xie J, Zhang P, Liu Y, Wu D, Ou X, Wang M, Yan W, Liu J, Tang J, Ni T, Ma C, Tang Q, Zhao S, Qi M
Journal of translational medicine 2025 Jul 10;23(1):778

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Intermediate filament IFFO1 negatively regulates the migration of lung cancer cells by inhibiting the IQGAP3-Cdc42 interaction.

Ye Y, Shen F, Yan M, Zhan C, Lv J, Zou M, Wang Z, Ning S, Gao Y, Wu J, Li W
Cell death & disease 2025 Jul 10;16(1):509

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Irinotecan alleviates chemoresistance to anthracyclines through the inhibition of AARS1-mediated BLM lactylation and homologous recombination repair.

Li X, Zhang C, Mei Y, Zhong W, Fan W, Liu L, Feng Z, Bai X, Liu C, Xiao M, He W, Lin T, Gou X
Signal transduction and targeted therapy 2025 Jul 10;10(1):214

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Consensus artificial intelligence-driven prognostic signature for predicting the prognosis of hepatocellular carcinoma: a multi-center and large-scale study.

Wen W, Wang R
NPJ precision oncology 2025 Jul 1;9(1):207

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IDO1 promotes Echinococcus multilocularis infection by regulating the formation of neutrophil extracellular traps.

Zhang H, Meng R, Zhang F, Chen A, Ge H, Chen W, Li Z, Fu Y
Veterinary research 2025 Jul 1;56(1):131

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Mechanistic study of butylphthalide in alleviating cerebral Edema after intracerebral Hemorrhage by regulating miR-7-5p expression.

Chen X, Wang S, Lei Q, Liu J, Lu W
Metabolic brain disease 2025 Jul 1;40(6):238

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Nicotinic acid riboside maintains NAD(+) homeostasis and ameliorates aging-associated NAD(+) decline.

Song WS, Shen X, Du K, Ramirez CB, Park SH, Cao Y, Le J, Bae H, Kim J, Chun Y, Khong NJ, Kim M, Jung S, Choi W, Lopez ML, Said Z, Song Z, Lee SG, Nicholas D, Sasaki Y, Milbrandt J, Imagawa DK, Skowronska-Krawczyk D, Chen D, Lee G, Jang C, Yang Q
Cell metabolism 2025 Jul 1;37(7):1499-1514.e4

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Identification of the pyroptosis, apoptosis, and necroptosis (PANoptosis) involved in osteogenic differentiation inhibition impaired by tumor necrosis factor-α.

Xia CL, Liang F, Li JX, Qu Y, Zhang W, Ou S, Yang Y, Qi Y, Xu CP
European journal of medical research 2025 Jul 1;30(1):541

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TBBPA-BDBPE induces ferroptosis in trophoblasts through chaperone-mediated autophagy of GPX4.

Mu Y, Wang K, Kang Y, Fang Z, Yu S, Zhou J, Li S, Zhang M
Ecotoxicology and environmental safety 2025 Jul 1;299:118425

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The addition of 5-aminolevulinic acid to HBSS protects testis grafts during hypothermic transportation: a novel preservation strategy.

Ma MH, Chen PG, He JX, Chen HC, Xu ZH, Lv LY, Li YQ, Liang XY, Liu GH
Asian journal of andrology 2025 Jul 1;27(4):454-463

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METTL3 regulates Ambra1 expression in an m6A-YTHDF2-dependent manner to promote mantle cell lymphoma progression.

Li S, Jiang Z, Wei W, Deng S, Duan T
Journal of translational medicine 2025 Jul 1;23(1):703

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Hepatocyte-expressed HERC2 enhances type I interferon-mediated anti-HBV immune response by promoting K33 ubiquitination of TBK1.

Zheng Z, Cao S, Liu Y, Luo J, Wang H, Lu X, Zhou J, Yuan S, Zuo D, Chen Q
Journal of immunology (Baltimore, Md. : 1950) 2025 Jul 1;214(7):1789-1801

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USP7 promotes PINK1/Parkin-dependent mitophagy to ameliorate cerebral ischemia-reperfusion injury by deubiquitinating and stabilizing SIRT1.

Hou D, Hu Y, Yun T, Yu D, Yang G
Brain research 2025 Jul 1;1858:149638

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Identification of potential biomarkers and mechanisms for keloid disorder based on comprehensive bioinformatics analysis and machine learning algorithms.

Zheng B, Qiao J, Yu X, Zhou H, Wang A, Zhang X
BMC medical genomics 2025 Jul 1;18(1):108

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Discovery of (E)-2-cyano-N-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)-3-(1H-indol-3-yl)acrylamide as a novel TDO inhibitor for cancer treatment.

Wang X, Wang X, Wang X, Xu K, Long J, Chen Y, Liu Y, Niu H, Zeng B, Fan Y
Bioorganic chemistry 2025 Jul 1;161:108555

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A novel carbamate-based hybrid derivative with anti-neuroinflammatory properties as a selective butyrylcholinesterase inhibitor for Alzheimer's disease therapy.

Liu X, Xu J, Yu C, Dai C, Chen J, Zhong J, Yang Y, Lin H, Chen X, Zhang Q, Dai L, Zhang J, Zha D, Ye ZC
Bioorganic chemistry 2025 Jul 1;161:108551

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Histone serotonylation promotes pancreatic cancer development via lipid metabolism remodeling.

Lin S, Tan S, Peng Y, Tulamaiti A, Du W, Ding K, Chen C, Wu J, Li H, Xu W, Sun J, Zhang XL, Zhang ZG, Zhao X
Nature communications 2025 Jul 1;16(1):5947

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Lysosome-mediated aggregation of galactose-deficient IgA1 with transferrin receptor 1 links to IgA nephropathy.

Si M, Fu J, Fang M, Lu Y, Huang J, Li H, Wang P, Liao M, Zhu J, Li P, Zhong W, Guo Z, Yang W, Ye Z, Hu H, Yu X
Nature communications 2025 Jul 1;16(1):5536

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ACSS2 protects against alcohol-induced hepatocyte ferroptosis through regulation of hepcidin expression.

Wang M, Wen X, Feng Z, Choubey M, Chen S, Pan R, Gong K, Tirumalasetty MB, Gao F, Liao C, Yin Z, Zhang S, He Y, Chen H, Cao Y, Miao QR, Hu W, Duan Y
Nature communications 2025 Jul 1;16(1):5491

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Impact of N-acetyltransferase 10 on macrophage activation and inflammation-induced cardiac dysfunction.

Xiao Z, Wei X, Li P, Chen R, Yu Z, Liang Y, Su Y, Ge J
Cell death & disease 2025 Jul 1;16(1):471

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SLC44A2 negatively regulates mitochondrial fatty acid oxidation to suppress colorectal progression by blocking the MUL1-CPT2 interaction.

Yang Y, Zheng L, He J, Wu T, Yang H, Zhang B, Zhou S, Lu Y, He X, Li J, Wang N
Cell death & disease 2025 Jul 1;16(1):468

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Identification of novel gene-based risk score for prognosis in prostate cancer.

Huang H, Sun X, Li P, Cai H, Xu L, Shi B, Qu S
Scientific reports 2025 Jul 1;15(1):22128

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H3 lysine 18 lactylation-mediated RRAS2 facilitates migration and invasion of head and neck squamous cell carcinoma.

Miao S, Lin L, Long M, Fu Y
Scientific reports 2025 Jul 1;15(1):21282

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DNMT3B aggravated renal fibrosis in diabetic kidney disease via activating Wnt/β-catenin signaling pathway.

Qu L, Wang T, Kong J, Wu X, Li Q, Long T, An X, Lu Y, Mu Y, Ran Y, Guo B, Shi M
Scientific reports 2025 Jul 1;15(1):21070

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The molecular subtype based on cell cycle-related gene signature predicts the prognosis and chemotherapy and immunotherapy response in gastric cancer.

Su R, Chen J, Dai C, Yin S, Chen H, Sun X, Fang Z, Zhang C, Chen J, Gu L
Scientific reports 2025 Jul 1;15(1):20858

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Region-specific roles of stress-activated protein kinase MKK7 in the developing and maturing murine brain.

Kofuji S, Qian Y, Nishina H
Scientific reports 2025 Jul 1;15(1):20504

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ADCY4 inhibits cAMP-induced growth of breast cancer by inactivating FAK/AKT and ERK signaling but is frequently silenced by DNA methylation.

Pan G, Huang M, Fu S, Wang Y, He L, Wu B, Yang J, Lin S, Fan Y
Scientific reports 2025 Jul 1;15(1):20426

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Upregulated Hexokinase-2 in Airway Epithelium Regulates Apoptosis and Drives Inflammation in Asthma via Peptidylprolyl Isomerase F.

Tian Z, Zheng H, Fan Y, Li B, Huang Z, Wang M, Zhang J, Zhao J, Wang S, Xie J
Cells 2025 Jul 1;14(13)

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The immune checkpoint molecule B7-H4 regulates β-cell mass and insulin secretion by modulating cholesterol metabolism through Stat5 signalling.

Xia F, Zhang Z, Qian Z, Fang X, Wang J, Wang Y, Sun G, Yu Y, Wang N, Zhen J, Liu Y, Lu Y
Molecular metabolism 2025 Jan;91:102069

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Impact of quercetin on autophagy and apoptosis induced by a high concentration of CuSO(4) in porcine ovarian granulosa cells.

Qi N, Wang B, Xing W, Li M, Liu J
Domestic animal endocrinology 2025 Jan;90:106881

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CDKN3 as a key regulator of G2M phase in triple-negative breast cancer: Insights from multi-transcriptomic analysis.

Ma H, Dong Y, Zheng J, Zhang S, Tang S, Wang J, Qu Z, Li X, Zeng L, Song K, Liu C, Shi L, Yin Q, Zheng X
IUBMB life 2025 Jan;77(1):e2922

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Targeting inhibition of T3JAM reduces brain cell ferroptosis in rat following ischemia/reperfusion via a mechanism involving prevention of TLR4-mediated iron overload.

Li Q, Zhang YY, Peng D, Liu HR, Wu L, Tang TT, Luo XJ
Archives of biochemistry and biophysics 2025 Jan;763:110225

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Dehydrocostus lactone suppresses gastric cancer progression by targeting ACLY to inhibit fatty acid synthesis and autophagic flux.

Chen Y, Shen J, Yuan M, Li H, Li Y, Zheng S, Han B, Zhang C, Liu S, Sun Q, Wu J
Journal of advanced research 2025 Jan;67:331-348

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Glycosylation of ceramide synthase 6 is required for its activity.

Straus AJ, Mavodza G, Senkal CE
Journal of lipid research 2025 Jan;66(1):100715

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BDNF-VGF Pathway Aggravates Incision Induced Acute Postoperative Pain via Upregulating the Neuroinflammation in Dorsal Root Ganglia.

Zhao W, Ma L, Deng D, Han L, Xu F, Zhang T, Wang Y, Huang S, Ding Y, Shu S, Chen X
Molecular neurobiology 2025 Jan;62(1):169-183

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H1N1 swine influenza viruses upregulate NEU1 expression through histone H3 acetylation regulated by HDAC2.

Zhao Q, Zhang J, Yang S, Bai X, Li Y, Zhang W, Zhang X
Virology 2025 Jan;601:110305

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Characteristics of polycystic ovary syndrome rat models induced by letrozole, testosterone propionate and high-fat diets.

Hu R, Huang Y, Liu Z, Dong H, Ma W, Song K, Xu X, Wu X, Geng Y, Li F, Zhang M, Song Y
Reproductive biomedicine online 2025 Jan;50(1):104296

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Humanin reduces nucleus pulposus cells ferroptosis to alleviate intervertebral disc degeneration: An in vitro and in vivo study.

Zhu D, Wang Z, Li Y, Chen S, Kang X
Journal of orthopaedic translation 2025 Jan;50:274-294

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Ginsenoside Rg1 improves hypoxia-induced pulmonary vascular endothelial dysfunction through TXNIP/NLRP3 pathway-modulated mitophagy.

Zhang R, Lu M, Ran C, Niu L, Qi Q, Wang H
Journal of ginseng research 2025 Jan;49(1):80-91

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Inhibiting the Otub1/phosphorylated STAT3 axis for the treatment of non-small cell lung cancer.

Liu ZY, Zhang YW, Zhuang HX, Ou YJ, Jiang QY, Li PF, He YM, Ren Y, Mao XL
Acta pharmacologica Sinica 2025 Jan;46(1):184-195

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Regulation of Erythroid Differentiation via the HIF1α-NFIL3-PIM1 Signaling Axis Under Hypoxia.

Yu HC, Cui R, Chen MY, Du XY, Bai QR, Zhang SL, Guo JJ, Tong FC, Wu J
Antioxidants & redox signaling 2025 Jan;42(1-3):36-52

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The IL-33/ST2 Axis Protects Retinal Ganglion Cells by Modulating the Astrocyte Response After Optic Nerve Injury.

Qian Z, Jiao M, Zhang N, Tang X, Liu S, Zhang F, Wang C, Zheng F
Neuroscience bulletin 2025 Jan;41(1):61-76

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UBE2D3 regulated by WTAP-mediated m6A modification inhibits temozolomide chemosensitivity in glioblastoma.

Bao J, Sun R, Pan Z, Wei S
Naunyn-Schmiedeberg's archives of pharmacology 2025 Jan;398(1):919-931

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Revitalizing premature ovarian failure: quercetin counteracts imatinib-induced apoptosis via the PI3K/AKT signaling pathway based on network pharmacology.

Ji M, Weng S, Li X, Xiao Q, Tong Y, Zhou Y, Luo T, Liu Z
Naunyn-Schmiedeberg's archives of pharmacology 2025 Jan;398(1):833-842

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Intestinal dysbiosis causes spatial memory impairment in alcohol-exposed male mice by inducing neuroinflammation.

Zhang X, Wang L, Xu C, Wang H, Yan A, Zheng Q, Wang K, Qiao X
Experimental neurology 2025 Jan;383:115028

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Lactiplantibacillus plantarum SG5 inhibits neuroinflammation in MPTP-induced PD mice through GLP-1/PGC-1α pathway.

Qi Y, Dong Y, Chen J, Xie S, Ma X, Yu X, Yu Y, Wang Y
Experimental neurology 2025 Jan;383:115001

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METTL5-mediated 18S rRNA m(6)A modification promotes corticospinal tract sprouting after unilateral traumatic brain injury.

Li Z, Jiang A, Fang J, Jiang Y, He W, Yan L, Qiu S, Qin B, Zhu Q, Wang H
Experimental neurology 2025 Jan;383:115000

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Blocking of SIRT7/FOXO3a axis by miR-152-3p enhances cisplatin sensitivity in breast cancer.

Shi X, Ji Y, Wu X, Du Y, Yan X, Wang Y, Xia X
The American journal of the medical sciences 2025 Jan;369(1):105-115

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N-Demethylsinomenine Relieves Neuropathic Pain in Male Mice Mainly via Regulating α2-Subtype GABA(A) Receptors.

Rong W, Qian X, Yin Y, Gu Y, Su W, Li JJ, Xu Y, Zhu H, Li J, Zhu Q
CNS neuroscience & therapeutics 2025 Jan;31(1):e70197

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NOTCH3 Mutation Causes Glymphatic Impairment and Promotes Brain Senescence in CADASIL.

Li C, Li H, Men X, Wang Y, Kang X, Hu M, Su X, Wang S, Lu D, Shen S, Huang H, Deng X, Liu Y, Zhang L, Cai W, Wu A, Lu Z
CNS neuroscience & therapeutics 2025 Jan;31(1):e70140

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E2F1 and E2F7 regulate gastric cancer cell proliferation, respectively, through transcriptional activation and transcriptional repression of MYBL2.

Wu T, Jiang F, Wu F, Zheng G, Li Y, Wu L
The Journal of biological chemistry 2025 Jan;301(1):108027

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The mechanism of Ca(2+)-independent activation of BKCa channels in mouse inner hair cells and the crucial role of the BK channels in auditory perception.

Shen ZS, Gan J, Xu B, Chen YL, Zhang FF, Ji JW, Chen DH, Qiao Y, Tang QY, Zhang Z
The Journal of biological chemistry 2025 Jan;301(1):107970

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TRIM2 promotes metabolic adaptation to glutamine deprivation via enhancement of CPT1A activity.

Liao K, Liu K, Wang Z, Zhao K, Mei Y
The FEBS journal 2025 Jan;292(2):275-293

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LAPTM5 Confers the Resistance to Venetoclax via Promoting the Autophagosome-Lysosome Fusion in Multiple Myeloma.

Li Y, Bai J, Liu D, Hao J, Yan R, Guo H, Huang Y, Yu H, Leng H, Zhou K, Liu M
Journal of cellular and molecular medicine 2025 Jan;29(1):e70331

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Astragalus polysaccharide alleviates mastitis disrupted by Staphylococcus aureus infection by regulating gut microbiota and SCFAs metabolism.

Li K, Ran X, Han J, Ding H, Wang X, Li Y, Guo W, Li X, Guo W, Fu S, Bi J
International journal of biological macromolecules 2025 Jan;286:138422

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Discovery of a novel Fam20C inhibitor for treatment of triple-negative breast cancer.

Lu Y, Zhen Y, Li Z, Luo B, Yin B, Zhang L
International journal of biological macromolecules 2025 Jan;286:138398

---

Single-cell analysis combined with transcriptome sequencing identifies autophagy hub genes in macrophages after spinal cord injury.

Ju C, Liu R, Ma Y, Dong H, Xu R, Hu H, Hao D
Clinical immunology (Orlando, Fla.) 2025 Jan;270:110412

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Comprehensive analysis of PSMG3 in pan-cancer and validation of its role in hepatocellular carcinoma.

Zheng M, Chen X, Xu Z, Ye Z, Zhong L, Chen Z, Chen G, Cai B
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2025 Jan;27(1):319-332

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AMPK-regulated glycerol excretion maintains metabolic crosstalk between reductive and energetic stress.

Zhai X, Yang R, Chu Q, Guo Z, Hou P, Li X, Bai C, Lu Z, Qiao L, Fu Y, Niu J, Li B
Nature cell biology 2025 Jan;27(1):141-153

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The synergistic effect of pulsed red light and leonurus inhibits primary dysmenorrhea induced by oxytocin in mice by modulating calcium signaling and inhibiting inflammatory responses.

Fu Q, Jiang H, Yang J, Qin H, Huo L, Ren Y, Lin S, Liu M, Yao J
Journal of photochemistry and photobiology. B, Biology 2025 Jan;262:113079

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Senolytics cocktail dasatinib and quercetin alleviate chondrocyte senescence and facet joint osteoarthritis in mice.

Zhao J, Zheng L, Dai G, Sun Y, He R, Liu Z, Jin Y, Wu T, Hu J, Cao Y, Duan C
The spine journal : official journal of the North American Spine Society 2025 Jan;25(1):184-198

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Leonurine restrains granulosa cell ferroptosis through SLC7A11/GPX4 axis to promote the treatment of polycystic ovary syndrome.

Huang X, Geng H, Liang C, Xiong X, Du X, Zhuan Q, Liu Z, Meng L, Zhou D, Zhang L, Fu X, Qi X, Hou Y
Free radical biology & medicine 2025 Jan;226:330-347

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Itaconic acid ameliorates necrotizing enterocolitis through the TFEB-mediated autophagy-lysosomal pathway.

Chen B, Liu Y, Luo S, Zhou J, Wang Y, He Q, Zhuang G, Hao H, Ma F, Xiao X, Li S
Free radical biology & medicine 2025 Jan;226:251-265

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Pink1/Parkin signaling mediates pineal mitochondrial autophagy dysfunction and its biological role in a comorbid rat model of depression and insomnia.

Li Z, Shu Y, Liu D, Xie S, Xian L, Luo J, Huang X, Jiang H
Brain research bulletin 2025 Jan;220:111141

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PRRSV-2 nsp2 Ignites NLRP3 inflammasome through IKKβ-dependent dispersed trans-Golgi network translocation.

Zhang L, Gao Y, Zhou H, Liang X, Jiang X, Gong W, Sun Y, Zhang D, Wang X, Nauwynck H, Bai J, Jiang P
PLoS pathogens 2025 Jan;21(1):e1012915

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Calcium-mediated mitochondrial fission and mitophagy drive glycolysis to facilitate arterivirus proliferation.

Sun Z, Ma Z, Cao W, Jiang C, Guo L, Liu K, Gao Y, Bai J, Pi J, Jiang P, Liu X
PLoS pathogens 2025 Jan;21(1):e1012872

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A mitochondria-to-nucleus regulation mediated by the nuclear-translocated mitochondrial lncRNAs.

Li J, Bai R, Zhou Y, Song X, Li L
PLoS genetics 2025 Jan;21(1):e1011580

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GORASP2 promotes phagophore closure and autophagosome maturation into autolysosomes.

Xing Y, Huang L, Jian Y, Zhang Z, Zhao X, Zhang X, Fu T, Zhang Y, Wang Y, Zhang X
Autophagy 2025 Jan;21(1):37-53

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miR-508-5p suppresses osteogenic differentiation of human periodontal ligament stem cells via targeting sex-determining region Y-related HMG-box 11.

Guo J, Ouyang XY, Liu JR, Liu WY, Wang YB
Journal of dental sciences 2025 Jan;20(1):201-211

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Hesperitin prevents non-alcoholic steatohepatitis by modulating mitochondrial dynamics and mitophagy via the AMPKα-Drp1/PINK1-Parkin signaling pathway.

Chen S, Lu H, Yin G, Zhang X, Meng D, Yu W, Wang L, Liu H, Zhang F
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Jan;1870(1):159570

---

Research on the anti-hepatic fibrosis effects and active components of the medicinal plant Tithonia diversifolia.

Wang J, Li H, Wang T, Xie H, Ruan Y, Zhang C
Fitoterapia 2025 Jan;180:106317

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Adipose tissue macrophages-derived exosomal MiR-500a-5p under high glucose promotes adipocytes inflammation by suppressing Nrf2 expression.

Li YZ, Tian Y, Yang C, Liu YF, Qu SL, Huang L, Zhang C
The international journal of biochemistry & cell biology 2025 Jan;178:106713

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Neuronal TRPV1-CGRP axis regulates peripheral nerve regeneration through ERK/HIF-1 signaling pathway.

Che H, Du Y, Jiang Y, Zhu Z, Bai M, Zheng J, Yang M, Xiang L, Gong P
Journal of neurochemistry 2025 Jan;169(1):e16281

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Porphyromonas gingivalis-induced autophagy exacerbates abnormal lung homeostasis: An in vivo and in vitro study.

Zhao Q, Li W, Li W, Yang H, Wang X, Ding Z, Liu Z, Wang Z
Archives of oral biology 2025 Jan;169:106122

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PINK1 modulates Prdx2 to reduce lipotoxicity-induced apoptosis and attenuate cardiac dysfunction in heart failure mice with a preserved ejection fraction.

Zhang H, Xu T, Mei X, Zhao Q, Yang Q, Zeng X, Ma Z, Zhou H, Zeng Q, Xu D, Ren H
Clinical and translational medicine 2025 Jan;15(1):e70166

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Design, synthesis and pharmacological evaluation of 1,2,3,4-tetrahydrobenzofuro[2,3-c]pyridine derivatives as p21-activated kinase 4 inhibitors for treatment of pancreatic cancer.

Li Y, Fang Y, Chen X, Tong L, Feng F, Zhou Q, Chen S, Ding J, Xie H, Zhang A
Acta pharmaceutica Sinica. B 2025 Jan;15(1):438-466

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Reversing metabolic reprogramming by CPT1 inhibition with etomoxir promotes cardiomyocyte proliferation and heart regeneration via DUSP1 ADP-ribosylation-mediated p38 MAPK phosphorylation.

Tang L, Shi Y, Liao Q, Wang F, Wu H, Ren H, Wang X, Fu W, Shou J, Wang WE, Jose PA, Yang Y, Zeng C
Acta pharmaceutica Sinica. B 2025 Jan;15(1):256-277

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Identifying Potential Drug Targets for Keloid: A Mendelian Randomization Study.

Wang Y, Wang X, Yuan Z, Liu F, Luo X, Yang J
The Journal of investigative dermatology 2025 Jan;145(1):77-84.e6

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Mitochondrial-Targeting Mesoporous Polydopamine Nanoparticles for Reducing Kidney Injury Caused by Depleted Uranium.

Li W, Shen L, Fu S, Li Y, Huang F, Li Q, Lin Q, Liu H, Wang Q, Chen L, Tan H, Li J, Zhao Y, Ran Y, Hao Y
Advanced healthcare materials 2025 Jan;14(2):e2403015

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Magnesium-Impregnated Membrane Promotes Bone Regeneration in Rat Skull Defect by N-Linked Glycosylation of SPARC via MagT1.

Chen W, Lu H, Yu W, Huang L, Bian M, Wang N, Xiang X, Mo G, Zhang C, Li Y, Jiang L, Zhang J
Advanced healthcare materials 2025 Jan;14(2):e2402705

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Pimpinellin mitigates DSS-induced ulcerative colitis in mice by reducing inflammation and regulating gut microbiota.

Lv B, Hou L, Zhang H, Hao C, Song Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156308

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Cyclovirobuxine D inhibits triple-negative breast cancer via YAP/TAZ suppression and activation of the FOXO3a/PINK1-Parkin pathway-induced mitophagy.

Wang ZQ, Wu ZX, Chen JW, Li HF, Wu HD, Bao JX, Cheng Y, Dai YW, Wang OC, Dai XX
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156287

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Xibining inhibition of the PI3K-AKT pathway reduces M1 macrophage polarization to ameliorate KOA synovial inflammation and nociceptive sensitization.

Jie L, Zhang L, Fu H, Kang J, Huang Z, Zhu Z, Yin S, Wu P, Wang P, Mei W, Li X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156281

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Effusol ameliorates ischemic stroke by targeting NLRP3 protein to regulate NLRP3 inflammasome-mediated pyroptosis.

Xu L, Li S, Qi J, Mi Y, Zhang Y, Yang Y, Wang Y, Zhou D, Li N, Hou Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156253

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9-PAHSA ameliorates microvascular damage during cardiac ischaemia/reperfusion injury by promoting LKB1/AMPK/ULK1-mediated autophagy-dependent STING degradation.

Liu W, Hu J, Wang Y, Gan T, Ding Y, Wang X, Xu Q, Xiong J, Xiong N, Lu S, Wang Y, Wang Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156241

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Long-Term Creatine Supplementation Improves Cognitive and Hippocampal Structural Plasticity Impairments in a D-Gal-Induced Aging Model via Increasing CK-BB Activity in the Brain.

Zhu Z, Zhang H, Li Q, Han X, Wang T, Zhang W, Chen F, Gu L, Yao Q, Chen L, Zhao Y
Food science & nutrition 2025 Jan;13(1):e4767

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Circ-ECH1 May Compete With miR-708-5p to Regulate Ntrk2 in Bronchopulmonary Dysplasia.

Cheng H, Li D, Tang Y, Hu T, Wu B
Journal of cellular biochemistry 2025 Jan;126(1):e30678

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The synergistic protective effects of paeoniflorin and β-ecdysterone against cardiac hypertrophy through suppressing oxidative stress and ferroptosis.

Yan P, Li X, He Y, Zhang Y, Wang Y, Liu J, Ren S, Wu D, Zhao Y, Ding L, Jia W, Lyu Y, Xiao D, Lin S, Lin Y
Cellular signalling 2025 Jan;125:111509

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Astrocyte-neuron communication through the complement C3-C3aR pathway in Parkinson's disease.

Chi X, Yin S, Sun Y, Kou L, Zou W, Wang Y, Jin Z, Wang T, Xia Y
Brain, behavior, and immunity 2025 Jan;123:229-243

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Hypoxia Induced Lnc191 Upregulation Dictates the Progression of Esophageal Squamous Cell Carcinoma by Activating GRP78/ERK Pathway.

Wei S, Fan X, Li X, Zhou W, Zhang Z, Dai S, Lv H, Liu Y, Shan B, Zhao L, Zhan Q, Song Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jan;12(4):e2406674

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γδ T Cell-mediated Tumor Immunity is Tightly Regulated by STING and TGF-β Signaling Pathways.

Luo J, Wang S, Yang Q, Fu Q, Zhu C, Li T, Yang S, Zhao Y, Guo R, Ben X, Zheng Y, Li S, Yang G, Zhang H, Xiao H, Jiang Z, Yan N, Kabelitz D, Sun G, Granot Z, Lu L, You F, Hao J, Yin Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jan;12(2):e2404432

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Copper ions-photo dual-crosslinked alginate hydrogel for angiogenesis and osteogenesis.

Liu G, Ye S, Li Y, Yang J, Wang S, Liu Y, Yang S, Tian Y, Yin M, Cheng B
Journal of biomedical materials research. Part A 2025 Jan;113(1):e37790

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The impact of endogenous N/OFQ on DPN: Insights into lower limb blood flow regulation in rats.

Qin YJ, Zhang P, Zhang P, Li J, Yang Q, Sun JL, Liang YZ, Wang LL, Zhang LZ, Han Y
Neuropeptides 2025 Jan;109:102492

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Fatty acids promote migration of CD4(+) T cells through calcium release-activated calcium modulator ORAI1 sensitive glycolysis in dairy cows.

Zhang B, Wen J, Li M, Wang J, Ji Z, Lv X, Usman M, Mauck J, Loor JJ, Yang W, Wang G, Ma J, Xu C
Journal of dairy science 2025 Jan;108(1):856-867

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Morusin Reverses Epithelial-Mesenchymal Transition in Gallbladder Cancer Cells by Regulating STAT3/HIF-1α Signaling.

Ji L, Chai Y, Tong C, Hu Y, Li J, Lu B, Yu J
Chemical biology & drug design 2025 Jan;105(1):e70054

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Icariin improves learning and memory function by enhancing HRD1-mediated ubiquitination of amyloid precursor protein in APP/PS1 mice.

Chen X, Lin C, He C, Li K, Gao J, Gong Q, Li F
Journal of Alzheimer's disease : JAD 2025 Jan;103(2):616-626

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Effect of Mesenchymal Stem Cell-Derived Extracellular Vesicles Induced by Advanced Glycation End Products on Energy Metabolism in Vascular Endothelial Cells.

Liang J, Cheng S, Song Q, Tang Y, Wang Q, Chen H, Feng J, Yang L, Li S, Wang Z, Fan J, Huang C
Kidney international reports 2025 Jan;10(1):227-246

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Bardoxolone methyl triggers Ferroptosis in cardiomyocytes.

Li H, Hong M, Liu Y, Rahman SU, Li X, Zheng F
Human & experimental toxicology 2025 Jan-Dec;44:9603271251394706

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Halofuginone induces ERK phosphorylation and synergizes with trametinib in gastric cancer cells.

Sun Y, Wang P, Bai X, Tian L, Zhong Y
International journal of immunopathology and pharmacology 2025 Jan-Dec;39:3946320251359860

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Rapamycin ameliorates inflammatory pain via recovery of autophagy flux mediated by mammalian target of rapamycin (mTOR) signaling pathway in the rat spinal cord.

Zhang J, Chen S, Zhang R, Zheng X, Liu C, Zhang J, Zhang L, Yang Z, Wang L
International journal of immunopathology and pharmacology 2025 Jan-Dec;39:3946320251317284

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Comparative analysis of dorsal and tail skin reveals region-dependent heterogeneity in axolotl skin regeneration.

Yang L, Chen Q, Li J, Hu Y, Liu Y, Lu B, Pei S, Huang T, Liu Y, Fei JF
Cell transplantation 2025 Jan-Dec;34:9636897251348730

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Pharmacodynamics of huaier aqueous extract against papillary thyroid carcinoma in vivo and in vitro.

Xu FZ, Zheng LL, Qin JB, Li YX, Chen KH, Dai LH, Zhu QL, Sang JF
Integrative cancer therapies 2025 Jan-Dec;24:15347354251339073

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CXCL6 Orchestrates Macrophage-Driven Inflammation in Diabetic Kidney Disease and Represents a Druggable Target.

Huang Y, Sun Y, Guo D, Lin H, Wu L, Zhou P, Wu D, Sun J, Zhou H, Hu Z, Peng H
Kidney diseases (Basel, Switzerland) 2025 Jan-Dec;11(1):812-834

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Targeting CD44 and EpCAM with Antibody Dye Conjugates for the Photoimmunotherapy of Prostate Cancer.

Wolf I, Schultze-Seemann S, Gratzke C, Wolf P
Antibodies (Basel, Switzerland) 2025 Jan 9;14(1)

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A Disintegrin and Metalloproteinase 17 Disrupts Bovine Macrophage MER Proto-Oncogene Tyrosine Kinase Integrity to Impede Apoptotic Cell Clearance and Promote Inflammation in Clinical Mastitis.

Wang J, Li M, Zhao B, Chang R, Wu W, Zhang H, Usman M, Loor JJ, Xu C
Journal of agricultural and food chemistry 2025 Jan 8;73(1):549-561

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Ubiquitin specific peptidase 11 knockdown slows Huntington's disease progression via regulating mitochondrial dysfunction and neuronal damage depending on PTEN-mediated AKT pathway.

Gao B, Jing Y, Li X, Cong S
Molecular medicine (Cambridge, Mass.) 2025 Jan 8;31(1):7

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CASP5 associated with PANoptosis promotes tumorigenesis and progression of clear cell renal cell carcinoma.

Yang K, Wang Y, Jian Y, Wang B, Du H, Xia Y, Bi J, Guo M, Li Z, Wang N
Cancer cell international 2025 Jan 8;25(1):8

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S100P is a ferroptosis suppressor to facilitate hepatocellular carcinoma development by rewiring lipid metabolism.

Yang M, Cui W, Lv X, Xiong G, Sun C, Xuan H, Ma W, Cui X, Cheng Y, Han L, Chu B
Nature communications 2025 Jan 8;16(1):509

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Genetic code expansion reveals site-specific lactylation in living cells reshapes protein functions.

Shao C, Tang S, Yu S, Liu C, Zhang Y, Wan T, He Z, Yuan Q, Wu S, Zhang H, Wan N, Zhan M, Tan RX, Hao H, Ye H, Wang N
Nature communications 2025 Jan 8;16(1):227

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Identifying ADME-related gene signature for immune landscape and prognosis in KIRC by single-cell and spatial transcriptome analysis.

Wang H, Li F, Wang Q, Guo X, Chen X, Zou X, Yuan J
Scientific reports 2025 Jan 8;15(1):1294

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SIX1 aggravates the progression of spinal cord injury in mice by promoting M1 polarization of microglia.

Xu Z, Zhu M, Xie H, Zhu J, Zheng H, Liu X, Zhang Y, Liu J
Scientific reports 2025 Jan 8;15(1):1283

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Binding of LncDACH1 to dystrophin impairs the membrane trafficking of Nav1.5 protein and increases ventricular arrhythmia susceptibility.

Xue G, Yang J, Zhang Y, Yang Y, Zhang R, Li D, Tian T, Li J, Zhang X, Li C, Li X, Yang J, Shen K, Guo Y, Liu X, Yang G, Xuan L, Shan H, Lu Y, Baofeng Y, Pan Z
eLife 2025 Jan 7;12

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Ubiquitin ligase MARCH5 controls the formation of mitochondria-derived pre-peroxisomes.

Zheng J, Chen J, Cao Z, Wu K, Wang J, Guo Y, Zhuang M
Developmental cell 2025 Jan 6;60(1):30-39.e3

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Rapid turnover of CTLA4 is associated with a complex architecture of reversible ubiquitylation.

Tey PY, Dufner A, Knobeloch KP, Pruneda JN, Clague MJ, Urbé S
The Journal of cell biology 2025 Jan 6;224(1)

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Melittin suppresses aerobic glycolysis by regulating HSF1/PDK3 to increase chemosensitivity of NSCLC.

Wang Y, Yuan J, Liu J, Li X, Zhou C, Qian M, Zou Z, Lu C, Huang G, Jin M
European journal of pharmacology 2025 Jan 5;986:177084

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Diosgenin attenuates nonalcoholic fatty liver disease through mTOR-mediated inhibition of lipid accumulation and inflammation.

Yin G, Liang H, Cheng Y, Chen S, Zhang X, Meng D, Yu W, Liu H, Song C, Zhang F
Chemico-biological interactions 2025 Jan 5;405:111306

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miR-26a-5p/ADAM17-Mediated Proteolysis of TREM2 Regulates Neuroinflammation in Hypertensive Mice Following Lead Exposure.

Wang Y, Wang Z, Hao H, Zhao Y, Wang J, Wang W
Toxics 2025 Jan 5;13(1)

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D-ribose-5-phosphate inactivates YAP and functions as a metabolic checkpoint.

Tu CE, Liu YF, Liu HW, Jiao CM, Liu Q, Hung MC, Li P, Wan XB, Fan XJ, Wang YL
Journal of hematology & oncology 2025 Jan 4;18(1):2

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Intestinal Barrier Damage and Growth Retardation Caused by Exposure to Polystyrene Nanoplastics Through Lactation Milk in Developing Mice.

Zhou C, Wu H, Zhang L, Xiao X, Wang X, Li M, Cai R, You J, Chen Q, Yang Y, Tian X, Bai Q, Chen Y, Bao H, Liu T
Nanomaterials (Basel, Switzerland) 2025 Jan 4;15(1)

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FSTL1 and TLR4 interact with PEDV structural proteins to promote virus adsorption to host cells.

Liu C, Kong N, Liu H, Zhang Y, Qin W, Zhao W, Yang X, Wang Y, Cao X, Liu T, Liu Y, Sun H, Tong W, Yu H, Zheng H, Lan D, Xie S, Tong G, Shan T
Journal of virology 2025 Jan 31;99(1):e0183724

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Myeloid cell-derived apCAFs promote HNSCC progression by regulating proportion of CD4(+) and CD8(+) T cells.

Ren F, Meng L, Zheng S, Cui J, Song S, Li X, Wang D, Li X, Liu Q, Bu W, Sun H
Journal of experimental & clinical cancer research : CR 2025 Jan 31;44(1):33

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MYBL2 promotes proliferation of clear cell renal cell carcinoma by regulating TOP2A and activating AKT/mTOR signaling pathway.

Huang Y, Xi X, Ye Z, Zhang C, Jiang Y, Yu F, Huang G
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jan 31;39(2):e70330

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Danhong injection modulates microglial polarization and neuroinflammation via the JUNB/NF-κB pathway in ischemic stroke.

Xie M, Huang H, Lu Y, Chen L, Wang S, Xian M
Journal of ethnopharmacology 2025 Jan 31;340:119247

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Real-world of Limosilactobacillus reuteri in mitigation of acute experimental colitis.

Yue N, Zhao H, Hu P, Zhang Y, Tian C, Kong C, Mai Z, Huang L, Luo Q, Wei D, Shi R, Tang S, Nie Y, Liang Y, Yao J, Wang L, Li D
Journal of nanobiotechnology 2025 Jan 31;23(1):65

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Hsa_circ_0001304 promotes vascular neointimal hyperplasia accompanied by autophagy activation.

Mu SQ, Lin JJ, Wang Y, Yang LY, Wang S, Wang ZY, Zhao AQ, Luo WJ, Dong ZQ, Cao YG, Jiang ZA, Wang SF, Cao SH, Meng L, Li Y, Yang SY, Sun SG
Communications biology 2025 Jan 30;8(1):146

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Drug pairs of Huangqi and Dnggui alleviates pyroptosis by promoting autophagy activity via AMPK/mTOR signaling pathway in middle-cerebral artery occlusion/reperfusion in rats.

Liu L, Wang R, Gao W, Hou X, Jin X, Zhao Y, Zhou X, Zhang Y
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):118982

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Hosta plantaginea (Lam.) Aschers flower modulates inflammation and amino acid metabolism by inhibiting NF-κB/MAPK/JAK-STAT/PI3K-Akt and AMPK pathways to alleviate benign prostatic hyperplasia in rats.

Wang H, Mu Z, Liang J, Li X, Yang L, He J
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):118970

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Cimicifuga heracleifolia kom. Attenuates ulcerative colitis through the PI3K/AKT/NF-κB signaling pathway.

Wu XY, Dong QW, Zhang YB, Li JX, Zhang MQ, Zhang DQ, Cui YL
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):118892

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Simiao Wan attenuates high-fat diet-induced hyperlipidemia in mice by modulating the gut microbiota-bile acid axis.

Wang K, Xu W, He W, Ding M, Xia T, Tan X
Journal of ethnopharmacology 2025 Jan 30;337(Pt 2):118868

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Extract of Nanhaia speciosa J. Compton & Schrire alleviates LPS-induced acute lung injury via the NF-κB/Nrf2/AQPs pathway.

Zhou S, Hu Y, Liu L, Li L, Deng F, Mo L, Huang H, Liang Q
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118831

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Chaihu Guizhi Decoction prevents cognitive, memory impairments and sensorimotor gating deficit induced by N-methyl-d-aspartate receptor antibody in mice.

Zhu X, Huang Y, Qiu J, Zhong Z, Peng Y, Liang X, Chen J, Zhou J, Liang X, Wang H, Xie W, Ding Y
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118806

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Ethyl acetate fraction of Thesium chinense Turcz. alleviates chronic obstructive pulmonary disease through inhibition of ferroptosis mediated by activating Nrf2/SLC7A11/GPX4 axis.

Liu MJ, Xu ZP, Guan YQ, Wang YY, Wen XS, Li GH, Wang XN, Shen T
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118776

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Jiedu Xiaozheng Yin extract targets cancer stem cells by Wnt signaling pathway in colorectal cancer.

Feng H, Yang Y, Chen H, Zhang Z, Zeng J, Huang Y, Yang X, Yang L, Du J, Cao Z
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118710

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Hyperoxia-activated Nrf2 regulates ferroptosis in intestinal epithelial cells and intervenes in inflammatory reaction through COX-2/PGE2/EP2 pathway.

Liu Y, Li T, Niu C, Yuan Z, Sun S, Liu D
Molecular medicine (Cambridge, Mass.) 2025 Jan 3;31(1):1

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An injectable hydrogel loaded with Icariin attenuates cartilage damage in rabbit knee osteoarthritis via Wnt/β-catenin signaling pathway.

Zheng H, Qu L, Yang L, Xie X, Song L, Xie Q
International immunopharmacology 2025 Jan 3;145:113725

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The impact of POSTN on tumor cell behavior and the tumor microenvironment in lung adenocarcinoma.

Sun D, Lu J, Tian H, Li H, Chen X, Hua F, Yang W, Yu J, Chen D
International immunopharmacology 2025 Jan 3;145:113713

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Natural Protein-Based Multifunctional Hydrogel Dressing Formed by Rapid Photocuring and Zinc Ion Coordination to Accelerate Wound Healing.

Li Q, Hou Y, Sun D, Zhu C, Wu R, Feng G, Zhang L, Song Y
ACS applied materials & interfaces 2025 Jan 29;17(4):5719-5734

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The di-leucine motif in the host defense peptide LL-37 is essential for initiation of autophagy in human macrophages.

Rekha RS, Padhi A, Frengen N, Hauenstein J, Végvári Á, Agerberth B, Månsson R, Guðmundsson GH, Bergman P
Cell reports 2025 Jan 28;44(1):115031

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The Role of Elacridar, a P-gp Inhibitor, in the Re-Sensitization of PAC-Resistant Ovarian Cancer Cell Lines to Cytotoxic Drugs in 2D and 3D Cell Culture Models.

Stasiak P, Sopel J, Lipowicz JM, Rawłuszko-Wieczorek AA, Korbecki J, Januchowski R
International journal of molecular sciences 2025 Jan 28;26(3)

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Predictive role of SLC1A5 in neuroblastoma prognosis and immunotherapy.

Cheng J, Sun M, Dong X, Yang Y, Qin X, Zhou X, Fu Y, Wang Y, Wang J, Zhang D
BMC cancer 2025 Jan 28;25(1):161

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DRAM1 enhances the proliferation and metastasis of gastric cancer through the PI3K/AKT/mTOR signaling pathway and energy metabolism.

Wu X, Li Y, Wang W, Xu J, Zhao B, Sun W, Ge D, Xiong L, Dou X, Zou X, Wang L, Chen M
Scientific reports 2025 Jan 28;15(1):3542

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hUC-MSC preserves erectile function by restoring mitochondrial mass of penile smooth muscle cells in a rat model of cavernous nerve injury via SIRT1/PGC-1a/TFAM signaling.

Yang M, Chen X, Zhang M, Zhang X, Xiao D, Xu H, Lu M
Biological research 2025 Jan 27;58(1):8

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Analysis of the potential biological mechanisms of geniposide on renal fibrosis by network pharmacology and experimental verification.

Liu M, Zhao W, Shi R, Wang Z, Li X, Wang D
BMC pharmacology & toxicology 2025 Jan 27;26(1):17

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Curcumin prevents neurodegeneration by blocking HDAC6-NLRP3 pathway-dependent neuroinflammation in Parkinson's disease.

Cai Z, Liang C, Huang K, Luo J, Lu R, Lai Y, Zheng D, Lin Z, Zhong J, Dai J, Huang J, Zhang H, Chen J
International immunopharmacology 2025 Jan 27;146:113928

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Extracellular vesicles from adipose-derived stem cell alleviate diabetic cardiomyopathy by regulating Chit1/NLRP3/Caspase-1-Mediated pyroptosis.

Zhang Y, Zhang L, Li P, Qiu L, Qu Y, Wu Y, Song H
International immunopharmacology 2025 Jan 27;146:113860

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GDF15-mediated enhancement of the Warburg effect sustains multiple myeloma growth via TGFβ signaling pathway.

Xue W, Li Y, Ma Y, Zhang F
Cancer & metabolism 2025 Jan 27;13(1):3

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ROS-regulated SUR1-TRPM4 drives persistent activation of NLRP3 inflammasome in microglia after whole-brain radiation.

Chang Y, He Y, Wang D, Zhang K, Zhang Y, Li Z, Zeng S, Xiao S, Pan S, Huang K
Acta neuropathologica communications 2025 Jan 27;13(1):16

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NAD+ Suppresses EV-D68 Infection by Enhancing Anti-Viral Effect of SIRT1.

Wang Y, Li H, Huang X, Huang Y, Lv M, Tang H, Han X, Liu J, Liang Y, Zang G, Lu N, Zhang G
Viruses 2025 Jan 26;17(2)

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Arsenic exposure accelerates type 1 diabetes mellitus progression via pyroptosis pathway in mice.

Lei L, Chen M, Qin C, Cai L, Liang B
Chemico-biological interactions 2025 Jan 25;406:111348

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The injury effect of osteopontin in sepsis-associated lung injury.

Wang Q, Yu Z, Song Z, Lu X, Li Z, Pi D, Li J, Xu F
Journal of inflammation (London, England) 2025 Jan 24;22(1):4

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Development of Sheep Intestinal Organoids for Studying Deoxynivalenol-Induced Toxicity.

Wang H, He X, Zhang M, Fan N, Yang Z, Shen T, Guo J, Song Y, Cao G, Liu Y, Li X, Nashun B
International journal of molecular sciences 2025 Jan 23;26(3)

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Integrated analysis of bioinformatics, mendelian randomization, and experimental validation reveals novel diagnostic and therapeutic targets for osteoarthritis: progesterone as a potential therapeutic agent.

Weng Z, Wang C, Liu B, Yang Y, Zhang Y, Zhang C
Journal of orthopaedic surgery and research 2025 Jan 23;20(1):85

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ROR1 CAR-T cells and ferroptosis inducers orchestrate tumor ferroptosis via PC-PUFA2.

Li D, Zhang W, Wang R, Xie S, Wang Y, Guo W, Huang Z, Lu C, Shan L, Liu H, Ma L, Hou X, Xu Z, Wang J
Biomarker research 2025 Jan 23;13(1):17

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Exploration of the Fasting Hypoglycemic Mechanism of Casein Hydrolysate Enriched with Glu/Gln and Glu/Gln-Containing Peptides in db/db Diabetic-like Mice Using Multiomics Analysis.

Wang C, Xu R, Udenigwe CC, Lin L, Zheng L, Zhao M
Journal of agricultural and food chemistry 2025 Jan 22;73(3):1902-1916

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Tensile force promotes osteogenic differentiation via ephrinB2-EphB4 signaling pathway in orthodontic tooth movement.

Yu H, Wei X, Jiang H, Qi H, Zhang Y, Hu M
BMC oral health 2025 Jan 22;25(1):118

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Glutamine-glutamate centered metabolism as the potential therapeutic target against Japanese encephalitis virus-induced encephalitis.

Li M, Yuan H, Yang X, Lei Y, Lian J
Cell & bioscience 2025 Jan 22;15(1):6

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Multicilia dynamically transduce Shh signaling to regulate choroid plexus functions.

Mao S, Song R, Jin S, Pang S, Jovanovic A, Zimmerman A, Li P, Wu X, Wendland MF, Lin K, Chen WC, Choksi SP, Chen G, Holtzman MJ, Reiter JF, Wan Y, Xuan Z, Xiang YK, Xu CS, Upadhyayula S, Hess HF, He L
bioRxiv : the preprint server for biology 2025 Jan 22;

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Bisphenol S impairs oocyte quality by inducing gut microbiota dysbiosis.

Zhang J, Yu X, Li W, Jiang Y, Zhang L, Wang S
mSystems 2025 Jan 21;10(1):e0091224

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Downregulation of ferroptosis-related ATF3 alleviates lupus nephritis progression.

Xiao G, Tang S, Zhang Y, Yuan Q, Sun D, Wang W
Gene 2025 Jan 20;934:149009

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Platelet Membrane-Coated HGF-PLGA Nanoparticles Promote Therapeutic Angiogenesis and Tissue Perfusion Recovery in Ischemic Hindlimbs.

Wang P, Di X, Li F, Rong Z, Lian W, Li Z, Chen T, Wang W, Zhong Q, Sun G, Ni L, Liu C
ACS applied bio materials 2025 Jan 20;8(1):399-409

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Hydrogel loaded with cerium-manganese nanoparticles and nerve growth factor enhances spinal cord injury repair by modulating immune microenvironment and promoting neuronal regeneration.

Gong Z, Chen Z, Li D, Lu X, Wu J, Sun H, Wang X, Liu S, Xia X, Lu F, Jiang J, Sun C, Wang H, Zeng F, Ma X
Journal of nanobiotechnology 2025 Jan 20;23(1):29

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Palmitoylation-dependent regulation of GPX4 suppresses ferroptosis.

Huang B, Wang H, Liu S, Hao M, Luo D, Zhou Y, Huang Y, Nian Y, Zhang L, Chu B, Yin C
Nature communications 2025 Jan 20;16(1):867

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Targeted Degradation of SOS1 Exhibits Potent Anticancer Activity and Overcomes Resistance in KRAS-Mutant Tumors and BCR-ABL-Positive Leukemia.

Luo Z, Lin C, Yu C, Yuan C, Wu W, Xu X, Sun R, Jia Y, Wang Y, Shen J, Wang D, Wang S, Jiang H, Jiang B, Yang X, Xie C
Cancer research 2025 Jan 2;85(1):101-117

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DNA-Dependent Protein Kinase Catalytic Subunit Prevents Ferroptosis in Retinal Pigment Epithelial Cells.

Wang X, Wang X, Zhao Z, Wang Q, Zhu X, Ou Q, Xu JY, Lu L, Gao F, Wang J, Bi Y, Xu GT, Jin C, Tian H
Investigative ophthalmology & visual science 2025 Jan 2;66(1):50

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Blue Light Damages Retinal Ganglion Cells Via Endoplasmic Reticulum Stress and Autophagy in Chickens.

Pan D, Hu G, Li J, Wang Z, Chen Y, Cao J
Investigative ophthalmology & visual science 2025 Jan 2;66(1):3

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Peroxiredoxin 6 maintains mitochondrial homeostasis and promotes tumor progression through ROS/JNK/p38 MAPK signaling pathway in multiple myeloma.

Gao D, Lv Y, Hong F, Wu D, Wang T, Gao G, Lin Z, Yang R, Hu J, He A, Zhang P
Scientific reports 2025 Jan 2;15(1):70

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Bi-allelic variants in DAP3 result in reduced assembly of the mitoribosomal small subunit with altered apoptosis and a Perrault-syndrome-spectrum phenotype.

Smith TB, Kopajtich R, Demain LAM, Rea A, Thomas HB, Schiff M, Beetz C, Joss S, Conway GS, Shukla A, Yeole M, Radhakrishnan P, Azzouz H, Ben Chehida A, Elmaleh-Bergès M, Glasgow RIC, Thompson K, Oláhová M, He L, Jenkinson EM, Jahic A, Belyantseva IA, Barzik M, Urquhart JE, O'Sullivan J, Williams SG, Bhaskar SS, Carrera S, Blakes AJM, Banka S, Yue WW, Ellingford JM, Houlden H, DDD Study, Munro KJ, Friedman TB, Taylor RW, Prokisch H, O'Keefe RT, Newman WG
American journal of human genetics 2025 Jan 2;112(1):59-74

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Inhibition of KLF5 promotes ferroptosis via the ZEB1/HMOX1 axis to enhance sensitivity to oxaliplatin in cancer cells.

Zhang Z, Xu H, He J, Hu Q, Liu Y, Xu Z, Lou W, Wu W, Zhang L, Pu N, Shi C, Xu Y, Wang W, Liu L
Cell death & disease 2025 Jan 18;16(1):28

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Proteomic analysis of spinal dorsal horn in prior exercise protection against neuropathic pain.

Chen B, Guo J, Gong C, Zhu C, Wu Y, Wang S, Zheng Y, Lu H
Scientific reports 2025 Jan 18;15(1):2391

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Hypoxia-induced circPLOD2a/b promotes the aggressiveness of glioblastoma by suppressing XIRP1 through binding to HuR.

Yu A, Wang Y, Duan C, Qin J, Liao M, Zhu H, Lei J, Liu J, Yang Z, Yu L, Gui H, Xin J, Tao W, Bao W, Dong Z
Communications biology 2025 Jan 17;8(1):71

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Targeting ROR2 homooligomerization disrupts ROR2-dependent signaling and suppresses stem-like cell properties of human breast adenocarcinoma.

Leng F, Huang J, Wu L, Zhang J, Lin X, Deng R, Zhu J, Li Z, Li Z, Wang Y, Zhang H, Lu D, Kipps TJ, Zhang S
iScience 2025 Jan 17;28(1):111589

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Macrophage NLRP3 inflammasome mediates the effects of sympathetic nerve on cardiac remodeling in obese rats.

Xi Z, Shu L, Xiao L, Fang X, Dai M, Wang J, Wu Y, Zhang J, Bao M
Molecular and cellular endocrinology 2025 Jan 15;596:112417

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The Ku protein family regulates hyperglycemia-induced vascular endothelial cell inflammation by modulating P300 levels.

Cai Q, Zhao Q, Yang Q, Zhu M, Meng F, Jiang J
Experimental cell research 2025 Jan 15;444(2):114399

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Umbilical cord mesenchymal stem cell-derived exosomal Follistatin inhibits fibrosis and promotes muscle regeneration in mice by influencing Smad2 and AKT signaling.

Hu H, Yin Y, Zhou H, Jiang B, Cai T, Wu S, Guo S
Experimental cell research 2025 Jan 15;444(2):114396

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Delactylation diminished the growth inhibitory role of CA3 by restoring DUOX2 expression in hepatocellular carcinoma.

Yan J, Zhou Y, Xu J, Dong Y, Yang X, Yang X, Wu A, Chang S, Wang Y, Zhang Q, Ayaka T, Yu L, Zhao L, Meng H, Liu D
Experimental cell research 2025 Jan 15;444(2):114392

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Unraveling the mechanism of microRNA-134 in colon cancer progression: Targeting KRAS and PIK3CA for cell cycle control and histone deacetylase regulation.

Jothimani G, Das D, Pathak S, Malayaperumal S, Zhang H, Sun XF, Banerjee A
Experimental cell research 2025 Jan 15;444(2):114385

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SEMA3C promotes thyroid cancer via the Wnt/β-catenin pathway.

Li S, Cheng Y, Gao C, Yuan Q, Lu X
Experimental cell research 2025 Jan 15;444(2):114378

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Knockdown of PELI1 promotes Th2 and Treg cell differentiation in juvenile idiopathic arthritis.

Li D, Li X, Duan M, Xue X, Tang X, Nan N, Zhao R, Zhang W, Zhang W
Experimental cell research 2025 Jan 15;444(2):114360

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Mechanisms of pathogenicity in the hypertrophic cardiomyopathy-associated TNNI3 c.235C > T variant.

Zhang L, Ding F, Ren Z, Cheng W, Dai H, Liang Q, Kong F, Xu W, Wang M, Zhang Y, Tao Q
International journal of cardiology 2025 Jan 15;419:132627

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Low-intensity pulsed ultrasound enhances the osteogenic potential of PDLSCs-derived extracellular vesicles through COMP/PI3K/AKT.

Xiang M, Guo Q, Liu Y, Zhang G, Liao C, Xiao L, Xiang M, Long S, Long Q, Guan X, Liu J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jan 15;39(1):e70299

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CUMS induces depressive-like behaviors and cognition impairment by activating the ERS-NLRP3 signaling pathway in mice.

Hao R, Gao X, Lu Q, Zhao T, Lu X, Zhang F, Pei Y, Lang J, Liu H, Song J, Zhang Z
Journal of affective disorders 2025 Jan 15;369:547-558

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Downregulated DKK2 may serve as a molecular mechanism of high-fat diet-induced myocardial injury via Wnt/β-catenin pathway.

Wang Y, Chen D, Pu Y, Shi J, Yi C, Chen J, Yang G, Cui Y, Nie Y, Zhang L, Wei X, Yu Q
Life sciences 2025 Jan 15;361:123306

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Incompletely closed HIV-1(CH040) envelope glycoproteins resist broadly neutralizing antibodies while mediating efficient HIV-1 entry.

Parthasarathy D, Pickthorn S, Ahmed S, Mazurov D, Jeffy J, Shukla RK, Sharma A, Herschhorn A
Npj viruses 2025 Jan 15;3(1):3

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Lead-induced actin polymerization aggravates neutrophil extracellular trap formation and contributes to vascular inflammation.

Nong Q, Wu Y, Liu S, Tang Y, Wu J, Huang H, Hong J, Qin Y, Xu R, Zhao W, Chen B, Huang Z, Hu L, Zhao N, Huang Y
Ecotoxicology and environmental safety 2025 Jan 15;290:117598

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Discovery of phenazine derivatives as a new class of non-classical ferroptosis inhibitors and efficacy evaluation on a mouse model of liver injury.

Wu Y, Yang L, You J, Tian C, Yang S, Li L
European journal of medicinal chemistry 2025 Jan 15;282:117042

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Intestinal microbiota-mediated serum pharmacochemistry reveals hepatoprotective metabolites of Platycodonis Radix against APAP-induced liver injury.

Zhong YH, Wu XW, Zhang XY, Zhang SW, Feng Y, Zhang XM, Xu BB, Zhong GY, Huang HL, He JW, Zeng JX, Liang J
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2025 Jan 15;1251:124395

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Investigating POU3F4 in cancer: Expression patterns, prognostic implications, and functional roles in tumor immunity.

Chen W, Ji Y, Wang R, Ji R, Lin Y, Wu Y, Liu L, Sha T, Li W, Zhang L, Yang L, Zhang X, Song J
Heliyon 2025 Jan 15;11(1):e41587

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Elevated SREBP1 accelerates the initiation and growth of pancreatic cancer by targeting SOX9.

Zhou C, Feng Z, Qian W, Zhu Z, Cao R, Wang Q, Zhang W, Liu R, Wu S, Hao J, Wang Z, Ma Q, Wu Z, Li X
Biology direct 2025 Jan 14;20(1):6

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Infiltrating peripheral monocyte TREM-1 mediates dopaminergic neuron injury in substantia nigra of Parkinson's disease model mice.

Song W, Zhou ZM, Zhang LL, Shu HF, Xia JR, Qin X, Hua R, Zhang YM
Cell death & disease 2025 Jan 14;16(1):18

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Role of the Dorsal Cortex of the Inferior Colliculus in the Precedence Effect.

Dai JS, Ge XY, Zhou M, Xu ZD, Zhao ZH, Zhang J, Wang NY
Medical science monitor : international medical journal of experimental and clinical research 2025 Jan 13;31:e945605

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Targeting deubiquitinase USP7-mediated stabilization of XPO1 contributes to the anti-myeloma effects of selinexor.

Wang J, Chen M, Jiang J, Wan Y, Li X, Zhang M, Xiao F, Zhong L, Zhong H, Qin Z, Hou J
Journal of translational medicine 2025 Jan 13;23(1):62

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Ghrelin Induces Ferroptosis Resistance and M2 Polarization of Microglia to Alleviate Neuroinflammation and Cognitive Impairment in Alzheimer's Disease.

Guo Y, Zhao J, Liu X, Lu P, Liang F, Wang X, Wu J, Hai Y
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2025 Jan 11;20(1):6

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METTL3 inhibition promotes radiosensitivity in hepatocellular carcinoma through regulation of SLC7A11 expression.

Zhang C, Yang T, Chen H, Ding X, Chen H, Liang Z, Zhao Y, Ma S, Liu X
Cell death & disease 2025 Jan 11;16(1):9

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SRC enhanced cisplatin resistance in bladder cancer by reprogramming glycolysis and pentose phosphate pathway.

Gong Y, Gao D, Shi Y, Fan G, Yu X, Yang E, Cheng H, Tian J, Ding H, Liu S, Fu S, Tao Y, Shui Y, Cheng L, Li L, Wang Z
Communications biology 2025 Jan 10;8(1):36

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SENP1 inhibits aerobic glycolysis in Aβ(1-42)-incubated astrocytes by promoting PUM2 deSUMOylation.

Liu Q, Jiang M, Wang Z, Meng J, Jia H, Li J, Lin J, Guo L, Gao L
Cell biology and toxicology 2025 Jan 10;41(1):28

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In vivo and in vitro study on the regulatory mechanism of XiaoChaiHu decoction on PANoptosis in sepsis-induced cardiomyopathy.

Wang Y, Fu X, Shang Z, Qiao Y, Liu Y, Zhou L, Liu D
Journal of ethnopharmacology 2025 Jan 10;336:118740

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Engeletin attenuates the inflammatory response via inhibiting TLR4-NFκB signaling pathway in Crohn's disease-like colitis.

Wei Z, Ni X, Cui H, Shu C, Peng Y, Liu J, Li Y
Journal of ethnopharmacology 2025 Jan 10;336:118733

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Sea buckthorn extract mitigates chronic obstructive pulmonary disease by suppression of ferroptosis via scavenging ROS and blocking p53/MAPK pathways.

Liu L, Wen T, Xiao Y, Chen H, Yang S, Shen X
Journal of ethnopharmacology 2025 Jan 10;336:118726

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Ilex cornuta leaves extracts ameliorate hyperuricemia by modulating uric acid transporters.

Mao Y, Xu H, Xia P
Journal of ethnopharmacology 2025 Jan 10;336:118618

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Cyclin G1 Regulates the Alveolarization in Models of Bronchopulmonary Dysplasia by Inhibiting AT2 Cell Proliferation.

Xu P, Zhuo W, Zhang P, Chen Y, Du Y, Li Y, Wang Y
Biomolecules 2025 Jan 10;15(1)

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Unveiling the interplay between hepatocyte SATB1 and innate immunity in autoimmune hepatitis.

Wang S, Huang Z, Nie S, Chen Y, Lei Y, Tu W, Luo M, Zhang ZG, Tian DA, Gong J, Liu M
International immunopharmacology 2025 Jan 10;144:113712

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Enhancing inhibitory effect in SMMC-7721 hepatoma cells through combined treatment of gallic acid and hUC-MSCs-Exos.

Zhang Q, Han L, Luo X, Bao Y, Wang S, Li T, Huo J, Meng X
International immunopharmacology 2025 Jan 10;144:113704

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Marein ameliorates the progression of osteoarthritis: An in vitro and in vivo studies.

Yin L, He Z, Fan Y, Niu Z, Yao L, Ding S, Chen J, Zhang Q, Tong Y, Bi Q, Cao L
International immunopharmacology 2025 Jan 10;144:113695

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RICTOR-mediated activation of AKT/mTOR signaling and autophagy inhibition promote osteoarthritis.

Xu J, Wang G, Hou Y, Sun K, Zheng Z, Guo Z, Hou L, Zhang X, Ruan Z, Ye Y, Guo F
International immunopharmacology 2025 Jan 10;144:113681

---

Downregulation of CD36 alleviates IgA nephropathy by promoting autophagy and inhibiting extracellular matrix accumulation in mesangial cells.

Zhang J, Wang Y, Chen C, Liu X, Liu X, Wu Y
International immunopharmacology 2025 Jan 10;144:113672

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Testosterone deficiency aggravates diet-induced non-alcoholic fatty liver disease by inducing hepatocyte ferroptosis via targeting BMAL1 in mice.

Fan Y, Ren Y, Deng L, Lv D, Chen J, Ling Y, Tu J, Xu X, Wang D, Cai Z
International immunopharmacology 2025 Jan 10;144:113641

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Overexpression of ALKBH5 alleviates LPS induced neuroinflammation via increasing NFKBIA.

Ye C, Huang X, Tong Y, Chen Y, Zhao X, Xie W, Wang Y, Wang J, Zhang A, Mo Y
International immunopharmacology 2025 Jan 10;144:113598

---

CBLN2 overexpression inhibits colorectal cancer progression and improves immunotherapy responses.

Wang Z, Pan H, Zhou J, Wan D
International immunopharmacology 2025 Jan 10;144:113566

---

Black phosphorus quantum dots induce lipid accumulation through PPARγ activation and mitochondrial dysfunction in adipocytes.

Zhu S, Ruan F, Ye L, Jiang S, Yang C, Zuo Z, He C
The Science of the total environment 2025 Jan 1;958:177972

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N 6-Methyladenosine Demethylase FTO Controls Macrophage Homeostasis in Diabetic Vasculopathy.

Feng S, Zhang Q, Liu Q, Huang C, Zhang H, Wang F, Zhu Y, Jian Q, Chen X, Jiang Q, Yan B
Diabetes 2025 Jan 1;74(1):82-95

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ACSL5 promotes lipid deposition and lipoapoptosis in proximal tubular epithelial cells of diabetic kidney disease.

Xi Y, Yang M, Deng Z, Xiong X, Wei L, Cai J, Tang C, Sun L
Molecular and cellular endocrinology 2025 Jan 1;595:112418

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The HIF2α-dependent upregulation of SETDB1 facilitates hypoxia-induced functional and phenotypical changes of pulmonary microvascular endothelial cells.

Zhou Y, Yang K, Zhang Z, Wei F, Chen L, Luo D, Yang Z, Zhao K, Xie N, Li W, Liang S, Xiong M, Tang H, Wang J, Zhang C
American journal of physiology. Cell physiology 2025 Jan 1;328(1):C40-C55

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Astragalus polysaccharide ameliorates diabetic retinopathy by inhibiting the SHH-Gli1-AQP1 signaling pathway in streptozotocin-induced type 2 diabetic rats.

Qu J, Wang B, Wang Y, Li H, An X
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2025 Jan 1;29(1):21-32

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CISD2-mediated mitochondrial dysfunction and iron redistribution contributes to ferroptosis in arsenic-induced nonalcoholic steatohepatitis.

Zhang J, Wang L, Lu Y, Zheng F, Ding X, Yao X, Bai J, Wang N, Yang G, Qiu T, Sun X
Ecotoxicology and environmental safety 2025 Jan 1;289:117694

---

Maternal exposure to polystyrene nanoplastics during gestation and lactation caused fertility decline in female mouse offspring.

Cheng X, Xue Y, Wang H, Ma Z, Hu N, Zhang C, Gao Y, Fan R, Hu L, Li J, Zhang D, Huang J, Fang S, Xiao R, He Y, Luo T, Zheng L
Ecotoxicology and environmental safety 2025 Jan 1;289:117632

---

Podophyllotoxin mediates hepatic toxicity via the C5a/C5aR/ROS/NLRP3 and cGMP/PKG/mTOR axis in rats based on toxicological evidence chain (TEC) concept by phosphoproteomic analysis.

Liu C, Huang X, Kong J, Li X, Wang Y, Zhang F, Duan J
Ecotoxicology and environmental safety 2025 Jan 1;289:117441

---

TRAF7 inhibits proliferation and migration of esophageal squamous cell carcinoma by ubiquitination-mediated degradation of SOX12.

Xie G, Wang N, Huang Y, Yang L, Zeng S, Jin J
Biochemistry and cell biology = Biochimie et biologie cellulaire 2025 Jan 1;103:1-13

---

SPHK1/S1PR1/PPAR-α axis restores TJs between uroepithelium providing new ideas for IC/BPS treatment.

Zhang J, Ge Q, Du T, Kuang Y, Fan Z, Jia X, Gu W, Chen Z, Wei Z, Shen B
Life science alliance 2025 Feb;8(2)

---

Collecting duct NCOR1 controls blood pressure by regulating mineralocorticoid receptor.

Sun K, Wang YL, Hou CC, Shang D, Du LJ, Bai L, Zhang XY, Hao CM, Duan SZ
Journal of advanced research 2025 Feb;68:75-87

---

DNA hypomethylation-mediated upregulation of GADD45B facilitates airway inflammation and epithelial cell senescence in COPD.

Zhan Y, Huang Q, Deng Z, Chen S, Yang R, Zhang J, Zhang Y, Peng M, Wu J, Gu Y, Zeng Z, Xie J
Journal of advanced research 2025 Feb;68:201-214

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Hypoxia-Challenged Pancreatic Adenocarcinoma Cell-Derived Exosomal circR3HCC1L Drives Tumor Growth Via Upregulating PKM2 Through Sequestering miR-873-5p.

Wang L, Zhou S, Ruan Y, Wu X, Zhang X, Li Y, Ying D, Lu Y, Tian Y, Cheng G, Zhang J, Lv K, Zhou X
Molecular biotechnology 2025 Feb;67(2):762-777

---

SUCLG1 promotes aerobic respiration and progression in plexiform neurofibroma.

Zhou Z, Li Q, Huo R
International journal of oncology 2025 Feb;66(2)

---

The Mechanism of TRIM21 Inhibiting the Invasion and Migration of ccRCC by Stabilizing ASS1.

Yang Z, Cai J, Li J, Liu X, Liu W, Cui K, Bai Z, Dong Y, Peng D, Duan Q, Shahzad A, Zhang Q
Molecular carcinogenesis 2025 Feb;64(2):260-278

---

CircKat6b Mediates the Antidepressant Effect of Esketamine by Regulating Astrocyte Function.

Hu N, Zheng Y, Liu X, Jia J, Feng J, Zhang C, Liu L, Wang X
Molecular neurobiology 2025 Feb;62(2):2587-2600

---

Omaveloxolone Ameliorates Cognitive Deficits by Inhibiting Apoptosis and Neuroinflammation in APP/PS1 Mice.

Liu Z, Jia J
Molecular neurobiology 2025 Feb;62(2):2191-2202

---

Calorie Restriction Attenuates Memory Impairment and Reduces Neuroinflammation in Obese Aged Rats.

Jantsch J, da Silva Rodrigues F, Silva Dias V, de Farias Fraga G, Eller S, Giovenardi M, Guedes RP
Molecular neurobiology 2025 Feb;62(2):1788-1799

---

Galectin-1 Regulates Inflammatory Responses and Promotes Microglial M2 Polarization in Chronic Migraine.

Xiao Y, Han W, Yu M, Jiang J, Zhu Y
The European journal of neuroscience 2025 Feb;61(3):e70010

---

LINC01224 promotes the Warburg effect in gastric cancer by activating the miR-486-5p/PI3K axis.

Bin Y, Liu M, He R, Tang P, Qu W, Wu D, Tan L, Wang Q, Jiang P, Hu H
In vitro cellular & developmental biology. Animal 2025 Feb;61(2):228-244

---

MiR-146a-5p downregulated TRAF6/NF-κB p65 pathway to attenuate the injury of HT-22 cells induced by oxygen-glucose deprivation/reoxygenation.

Deng Y, Wang G, Hou D, Zhang L, Pei C, Yang G
In vitro cellular & developmental biology. Animal 2025 Feb;61(2):178-188

---

OPA3 inhibits the cGAS-STING pathway mediated by mtDNA stress to promote colorectal cancer progression.

Yin Y, Ma Z, Yuan S, Xu K, Wang X
In vitro cellular & developmental biology. Animal 2025 Feb;61(2):165-177

---

Aldosterone promotes calcification of vascular smooth muscle cells in mice through the AIF-1/Wnt/β-catenin signaling pathway.

Li X, Zhao Y, Jiang G
International urology and nephrology 2025 Feb;57(2):613-623

---

Methamphetamine inhibits huntingtin-associated protein 1-mediated tyrosine receptor kinase B endocytosis resulting the neuroprotective dysfunction of brain-derived neurotrophic factor.

Shen B, Wu Z, Lv M, Yang G, Cao Y, Zhang Y, Shu J, Dong W, Hou Z, Jing D, Zhang X, Hou Y, Xu J, Hong S, Li L
Toxicology 2025 Feb;511:154047

---

Acidosis induces autophagic cell death through ASIC1-mediated Akt/mTOR signaling in HT22 neurons.

Guo M, Qiu MY, Zeng L, Nie YX, Tang YL, Luo Y, Gu HF
Toxicology 2025 Feb;511:154045

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Tripartite motif-containing 32 regulated by miR-6236-p5 inhibited silica-induced apoptosis of alveolar macrophages.

Zhao M, Chen Q, Chen X, Gong S, Wang M, Zhao S, Wang S, Du W, Xu Y, Peng L, Yao Y
Toxicology 2025 Feb;511:154042

---

IGF2BP1 promotes endometriosis by enhancing m6A modification stability of HMGB1.

Wei X, Su Y, Tian W, Cheng L, Yin L, He X
The journal of obstetrics and gynaecology research 2025 Feb;51(2):e16242

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Investigation of oral toxicity of WS(2) nanosheets to mouse intestine: Pathological injury, trace element balance, lipid profile changes, and autophagy.

Zha X, Luo S, Wei L, Li F, Li Y, Cao Y
Journal of applied toxicology : JAT 2025 Feb;45(2):311-321

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Nicotinamide N-methyltransferase negatively regulates metastasis-promoting property of cancer-associated fibroblasts in lung adenocarcinoma.

Wang P, Wang G, Li H, Yuan Y, Chen H, Wang S, Sun Z, Meng F, Li Y, Yang F, Wang J, Chen K, Qiu M
Cancer communications (London, England) 2025 Feb;45(2):110-137

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Endothelial IGFBP6 suppresses vascular inflammation and atherosclerosis.

Su M, Zhao W, Jiang H, Zhao Y, Liao Z, Liu Z, Xu M, Jiang S, Wu L, Yang Y, Wang Z, Zeng Z, Fang Y, Tang C, Miller CL, Evans PC, Wang L, Banach M, Jo H, Berk BC, Offermanns S, Huang Y, Ge J, Xu S, Weng J
Nature cardiovascular research 2025 Feb;4(2):145-162

---

Uncovering the mechanisms of diosmin in treating obesity-related kidney injury based on network pharmacology, molecular docking, and in vitro validation.

Zhu JX, Chu F, Zhao WM, Shi R, Wang ZJ, Li XL, Zhu YY, Wang DG
Naunyn-Schmiedeberg's archives of pharmacology 2025 Feb;398(2):1973-1989

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Ginsenoside Rb3 Promotes Opa1-Mediated Regenerative Neurogenesis via Activating the Ido1 Pathway in Ischemic Stroke.

Wang L, Qin N, Gao S, Zhu T
Phytotherapy research : PTR 2025 Feb;39(2):564-580

---

Functionalized Nanozyme Microcapsules Targeting Deafness Prevention via Mitochondrial Homeostasis Remodeling.

Ge S, Sun A, Zhou X, Niu P, Chen Y, Bao X, Yu M, Zhong Z, Sun J, Li G
Advanced materials (Deerfield Beach, Fla.) 2025 Feb;37(5):e2413371

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Hydroxyacyl-coenzyme A dehydrogenase: A biomarker for authentication of death from mechanical asphyxia.

Wu T, Li W, Hu Y, Zhang D, Tian L, Xu H, Zhang F, Xiao B, Shi Y, Chen Y, Liao X, Ma K, Chen L
Forensic science international 2025 Feb;367:112371

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ARHGAP26 deficiency drives the oocyte aneuploidy and early embryonic development failure.

Li S, Zhang Y, Yuan R, Zhu S, Bai J, Miao Y, Ou X, Wang Q, Xiong B
Cell death and differentiation 2025 Feb;32(2):291-305

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Mechanism of Asperosaponin VI Related to EGFR/MMP9/AKT/PI3K Pathway in Treatment of Rheumtoid Arthritis.

Luo JF, Yu Y, Liu JX
Chinese journal of integrative medicine 2025 Feb;31(2):131-141

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Ophiopogon japonicus polysaccharide reduces doxorubicin-induced myocardial ferroptosis injury by activating Nrf2/GPX4 signaling and alleviating iron accumulation.

Chen Y, Ma L, Yan Y, Wang X, Cao L, Li Y, Li M
Molecular medicine reports 2025 Feb;31(2)

---

Negative air ions alleviate nicotine-induced renal damage of spontaneously hypertensive rats via inhibiting oxidative stress and TGF-β/Smad pathway.

Xiao S, Wei T, Xiao M, An Z, Shan M, Luo Z, Zhou J, Li N, Lu X
Ecotoxicology and environmental safety 2025 Feb;291:117882

---

Microplastic exposure induces HSP90α secretion and aggravates asthmatic airway remodeling via PI3K-Akt-mTOR pathway.

Xu M, Chen J, Gao L, Cai S, Dong H
Ecotoxicology and environmental safety 2025 Feb;291:117828

---

Bu Yang Huan Wu Prevents Osteogenic Effect of Muscle-Derived Stromal Cells via Regulating JAK/STAT Pathway.

Cao G, Zhang S, Liao Y, Yue C, Yang L, Guo J, Tong P, Tan H
Journal of cellular and molecular medicine 2025 Feb;29(3):e70413

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1α,25(OH)(2)D(3) improves 17β-estradiol secretion and potentially alleviates endoplasmic reticulum stress in muskrat granulosa cells.

Lu W, Shi X, Liu Y, Zhang H, Yuan Z, Han Y, Weng Q
Biochemical pharmacology 2025 Feb;232:116696

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Hyperlipidemia impairs bone repair and regeneration via miR-193a-3p/STMN1/PI3K/Akt axis.

Shang J, Li Z, Ma A, Zhu T, Ma G, Gui H, Ren H, Sun B, Wang W, Wang X, Liu C, Li C, Wang Z, Lan J
Biochemical pharmacology 2025 Feb;232:116693

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A quinolinyl analog of resveratrol improves neuronal damage after ischemic stroke by promoting Parkin-mediated mitophagy.

Meng Q, Mi Y, Xu L, Liu Y, Liang D, Wang Y, Wang Y, Liu Y, Chen G, Hou Y
Chinese journal of natural medicines 2025 Feb;23(2):214-224

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Demyelination-derived lysophosphatidylserine promotes microglial dysfunction and neuropathology in a mouse model of Alzheimer's disease.

Zhou Y, Huang Z, Lin B, Ma M, Hao Y, Liu J, Xu W, Huang G, Mo W, Wang X, Jiang W, Zhou R
Cellular & molecular immunology 2025 Feb;22(2):134-149

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The molecular receptor NKBB enhances the persistence and anti-hepatocellular carcinoma activity of GPC3 CAR-T cells.

Sui M, Liu T, Song X, Li J, Ding H, Liu Y, Wang X, Liu H, Xue Y, Qi J, Zhang M, Zhao S, Zhu Q
Pharmacological research 2025 Feb;212:107619

---

Lactylation of tau in human Alzheimer's disease brains.

Zhang X, Liu Y, Rekowski MJ, Wang N
Alzheimer's & dementia : the journal of the Alzheimer's Association 2025 Feb;21(2):e14481

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Roles of blood monocytes carrying TREM2(R47H) mutation in pathogenesis of Alzheimer's disease and its therapeutic potential in APP/PS1 mice.

Yu ZY, Liu J, Liu ZH, Liu XY, Tuo JM, Li JH, Tu YF, Tan Q, Ma YY, Bai YD, Xin JY, Huang S, Zeng GH, Shi AY, Wang J, Liu YH, Bu XL, Ye LL, Wan Y, Liu TF, Chen XW, Qiu ZL, Gao CY, Wang YJ
Alzheimer's & dementia : the journal of the Alzheimer's Association 2025 Feb;21(2):e14402

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Mir221- and Mir222-enriched adsc-exosomes mitigate PM exposure-exacerbated cardiac ischemia-reperfusion injury through the modulation of the BNIP3-MAP1LC3B-BBC3/PUMA pathway.

Lee TL, Shen WC, Chen YC, Lai TC, Lin SR, Lin SW, Yu IS, Yeh YH, Li TK, Lee IT, Lee CW, Chen YL
Autophagy 2025 Feb;21(2):374-393

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The prognostic and immune significance of Rab11A in pan-cancer and its function and mechanism underlying estrogen receptor targeting in breast cancer.

Li Y, Ding B, Wei M, Yang X, Fu R, Liu Y, Zhu L, Ding Y, Zhang W, Zhang G, Zhang S, Bu Y, He J, Deng J, Bao X, Hao J, Ma L
Asia-Pacific journal of clinical oncology 2025 Feb;21(1):12-30

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Xylooligosaccharide and Akkermansia muciniphila synergistically ameliorate insulin resistance by reshaping gut microbiota, improving intestinal barrier and regulating NKG2D/NKG2DL signaling in gestational diabetes mellitus mice.

Wang J, Wu Y, Yang J, Ying S, Luo H, Zha L, Li Q
Food research international (Ottawa, Ont.) 2025 Feb;201:115634

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Whole transcriptome and proteome analyses identify ncRNAs and mRNAs to predict competing endogenous RNA networks in hepatitis B virus-induced hepatocellular carcinoma.

Yan S, Fu P, Zhu Y, Li H, Shan R, Gong B
Microbial pathogenesis 2025 Feb;199:107248

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Engineered S. cerevisiae-pYD1-ScFv-AFB1 mitigates aflatoxin B1 toxicity via bio-binding and intestinal microenvironment repair.

Huang H, Li Z, Qi Z, Ma L, Hu G, Zou C, Chen T
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Feb;196:115232

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CDR1as Deficiency Prevents Photoreceptor Degeneration by Regulating miR-7a-5p/α-syn/Parthanatos Pathway in Retinal Detachment.

Jin F, Yan Y, Ye Z, Wang L, Deng C, Jiang J, Dong K
The American journal of pathology 2025 Feb;195(2):293-305

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The mRNA Stability of PIEZO1, Regulated by Methyltransferase-Like 3 via N(6)-Methylation of Adenosine Modification in a YT521-B Homology Domain Family 2-Dependent Manner, Facilitates the Progression of Diabetic Retinopathy.

Han N, Yu N, Yu L
The American journal of pathology 2025 Feb;195(2):265-280

---

Inhibiting IP6K1 confers atheroprotection by elevating circulating apolipoprotein A-I.

Liu X, Zhang Z, Aguirre T, Shipton ML, Fu L, Du J, Furkert D, Qi J, Chin AC, Riley AM, Liu T, Zhang X, Potter BVL, Fiedler D, Zhu Y, Fu C
Metabolism: clinical and experimental 2025 Feb;163:156098

---

Hydrogen sulfide alleviates endothelial glycocalyx damage and promotes placental angiogenesis in rats exposed to cigarette smoke.

Zhang K, Wu G, Chen Y, Hu Q, Li Y, Jiang X, Gu C, Zhang N, Zhao F
Nitric oxide : biology and chemistry 2025 Feb;154:115-127

---

METTL14-mediated m6A modification of ZFP14 inhibits clear cell renal cell carcinoma progression via promoting STAT3 ubiquitination.

Liu Z, Sun T, Zhang Z, Piao C, Kong C, Zhang X
Clinical and translational medicine 2025 Feb;15(2):e70232

---

Deubiquitinase JOSD2 alleviates colitis by inhibiting inflammation via deubiquitination of IMPDH2 in macrophages.

Liu X, Fang Y, Huang M, Tu S, Zheng B, Yuan H, Yu P, Lan M, Luo W, Zhou Y, Chen G, Shen Z, Wang Y, Liang G
Acta pharmaceutica Sinica. B 2025 Feb;15(2):1039-1055

---

Stigmasterol from Prunella vulgaris L. Alleviates LPS-induced mammary gland injury by inhibiting inflammation and ferroptosis.

Sun M, Xu D, Liu D, Ran X, Li F, Wang J, Ge Y, Liu Y, Guo W, Liu J, Cao Y, Fu S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Feb;137:156362

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Insulin-like growth factor-1 promotes the testicular sperm production by improving germ cell survival and proliferation in high-fat diet-treated male mice.

Liu G, Liu D, Zhu M, Zhang M, Li C, Xu X, Pan F
Andrology 2025 Feb;13(2):342-358

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Targeting Metabolic Adaptation of Colorectal Cancer with Vanadium-Doped Nanosystem to Enhance Chemotherapy and Immunotherapy.

Cheng Q, Chen Y, Zou D, Li Q, Shi X, Qin Q, Liu M, Wang L, Wang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(7):e2409329

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PNPO-Mediated Oxidation of DVL3 Promotes Multiple Myeloma Malignancy and Osteoclastogenesis by Activating the Wnt/β-Catenin Pathway.

Deng Z, Sun S, Zhou N, Peng Y, Cheng L, Yu X, Yuan Y, Guo M, Xu M, Cheng Y, Zhou F, Li N, Yang Y, Gu C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(5):e2407681

---

Shigella infection is facilitated by interaction of human enteric α-defensin 5 with colonic epithelial receptor P2Y11.

Xu D, Guo M, Xu X, Luo G, Liu Y, Bush SJ, Wang C, Xu T, Zeng W, Liao C, Wang Q, Zhao W, Zhao W, Liu Y, Li S, Zhao S, Jiu Y, Sauvonnet N, Lu W, Sansonetti PJ, Ye K
Nature microbiology 2025 Feb;10(2):509-526

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Engineered Bacillus subtilis WB600/ZD prevents Salmonella Infantis-induced intestinal inflammation and alters the colon microbiota in a mouse model.

Li W, Wang X, Chen K, Zhu Y, Yang G, Jin Y, Wang J
Veterinary research 2025 Feb 8;56(1):35

---

Mechanistic insights into PROS1 inhibition of bladder cancer progression and angiogenesis via the AKT/GSK3β/β-catenin pathway.

Fan XP, Wang JR, Chen SY, Li XR, Cao JL, Wang HB, Ding LY, Che TJ, Yang L
Scientific reports 2025 Feb 8;15(1):4748

---

The mitochondrial DNAJC co-chaperone TCAIM reduces α-ketoglutarate dehydrogenase protein levels to regulate metabolism.

Jiahui W, Xiang Y, Youhuan Z, Xiaomin M, Yuanzhu G, Dejian Z, Jie W, Yinkun F, Shi F, Juncheng S, Masha H, Marcia H, Peiyi W, Yingjie X, Wen Y
Molecular cell 2025 Feb 6;85(3):638-651.e9

---

Acetoacetate Ameliorates Hepatic Fibrosis by Targeting Peroxisome Proliferator-Activated Receptor Gamma to Restore Lipid Droplets in Activated Hepatic Stellate Cells.

Zhou Y, Wang F, Hu M, Xia S, Li Y, Zheng S, Zhang F
Pharmaceuticals (Basel, Switzerland) 2025 Feb 6;18(2)

---

Metal-organic framework-based nanoplatforms for synergistic anti-atherosclerosis therapy by regulating the PI3K/AKT/MSR1 pathway in macrophages.

Zeng C, Peng Z, Huang S, Xu Z, Peng Z, Wu Z, Lei J, Zhang X, Qin J, Ye K, Li B, Zhao Z, Pan Y, Yin M, Lu X
Nanoscale 2025 Feb 6;17(6):3071-3085

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Pore-Forming Protein LIN-24 Enhances Starvation Resilience in Caenorhabditis elegans by Modulating Lipid Metabolism and Mitochondrial Dynamics.

Lan X, Yang M, Wang J, Huang C, Wu A, Cui L, Guo Y, Zeng L, Guo X, Zhang Y, Xiang Y, Wang Q
Toxins 2025 Feb 6;17(2)

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Bergenin inhibits ferritinophagy and ferroptosis in cisplatin-induced acute kidney injury by activating the p-GSK3β/Nrf2/PPARγ pathway.

Hu J, Zhang Y, Zhang Y, Shi N, Miu Y, Huang J, Miao M, Ci X
International immunopharmacology 2025 Feb 6;147:114004

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Experimental study on the inhibitory effect of Halofuginone on NSCLC.

Han Y, Liu S, Zhu J, Liu P, Meng Z, Li Y, Li S, Fan F, Zhang M, Liu H
European journal of pharmacology 2025 Feb 5;988:177221

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Methanol Extract of Pueraria lobata (Willd.) Root and Its Active Ingredient, Puerarin, Induce Apoptosis in HeLa Cells and Attenuates Bacterial Vaginosis in Gardnerella vaginalis-Infected Mice.

Lee JH, Lim JY, Jeon YD, Kim DK, Lee DH
International journal of molecular sciences 2025 Feb 5;26(3)

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Edaravone dexborneol alleviates pericyte-mediated fibrosis depositing extracellular matrix through TGF-β1/IL-11 in cerebral small vessel disease.

Duan Q, Liu Z, Xing Y, Huang H, Zhu L, Liu J, He P, Ma G, Zhang Y, Nie K, Gao Y, Wang L
Journal of translational medicine 2025 Feb 5;23(1):161

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A Granzyme B-Cleavable T Cell-Targeted Bispecific Cell Vesicle Connector for Reversing New-Onset Type 1 Diabetes.

Wang Y, Sun Y, Zhang X, Wang S, Huang X, Xu K, Liu Y, Huang Y, Xu J, Wei X, Cheng H, Pan L, Wang J, Gu Z
Journal of the American Chemical Society 2025 Feb 5;147(5):4167-4179

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Hypoxia-Regulated CD44 and xCT Expression Contributes to Late Postoperative Epilepsy in Glioblastoma.

Kusakabe K, Inoue A, Ohnishi T, Nakamura Y, Ohtsuka Y, Nishikawa M, Yano H, Choudhury ME, Murata M, Matsumoto S, Suehiro S, Yamashita D, Shigekawa S, Watanabe H, Kunieda T
Biomedicines 2025 Feb 5;13(2)

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Nuclear GTPSCS functions as a lactyl-CoA synthetase to promote histone lactylation and gliomagenesis.

Liu R, Ren X, Park YE, Feng H, Sheng X, Song X, AminiTabrizi R, Shah H, Li L, Zhang Y, Abdullah KG, Dubois-Coyne S, Lin H, Cole PA, DeBerardinis RJ, McBrayer SK, Huang H, Zhao Y
Cell metabolism 2025 Feb 4;37(2):377-394.e9

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PKR Inhibition Prevents Neuroinflammation and Rescues Depressive-Like Behaviors via BDNF/TrkB Signaling.

Hu Y, Ali T, Mou S, Gong Q, Gao R, Luo Y, Li S, Ling L, Hao L
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2025 Feb 4;20(1):13

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Harnessing macrophage-drug conjugates for allogeneic cell-based therapy of solid tumors via the TRAIN mechanism.

Taciak B, Bialasek M, Kubiak M, Marszalek I, Gorczak M, Osadchuk O, Kurpiel D, Strzemecki D, Barwik K, Skorzynski M, Nowakowska J, Lipiński W, Kiraga Ł, Brancewicz J, Klopfleisch R, Krzemiński Ł, Gorka E, Smolarska A, Padzinska-Pruszynska I, Siemińska M, Guzek J, Kutner J, Kisiala M, Wozniak K, Parisi G, Piacentini R, Cassetta L, Forrester LM, Bodnar L, Weiss T, Boffi A, Kucharzewska P, Rygiel TP, Krol M
Nature communications 2025 Feb 4;16(1):1327

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Phillyrin ameliorates DSS-induced colitis in mice via modulating the gut microbiota and inhibiting the NF-κB/MLCK pathway.

Li T, Hu G, Fu S, Qin D, Song Z
Microbiology spectrum 2025 Feb 4;13(2):e0200624

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Deletion of Arntl, a component of the molecular clock, in adipocytes leads to cellular hypertrophy by increasing insulin sensitivity via FGF21.

Ishii H, Kitaura S, Wada T, Shimba S
Npj biological timing and sleep 2025 Feb 3;2(1)

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The alleviation by wheat and oat dietary fiber alone or combined of T2DM symptoms in db/db mice.

Liu X, Pang S, Song G, Wang Y, Fang W, Qi W
Food & function 2025 Feb 3;16(3):1142-1156

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FAM210B activates STAT1/IRF9/IFIT3 axis by upregulating IFN-α/β expression to impede the progression of lung adenocarcinoma.

Gao X, Huang D, Liu Y, Zhang G, Zheng X, Guan B, Chen A, Wu J, Luo SM, Liu Z, Chen L, Liu X, Jin J, Yin X, Sun Z, Zhang Y, Lu M, Zhang G, Liu W, Liu L
Cell death & disease 2025 Feb 3;16(1):63

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Structural basis for the ligand-dependent activation of heterodimeric AHR-ARNT complex.

Diao X, Shang Q, Guo M, Huang Y, Zhang M, Chen X, Liang Y, Sun X, Zhou F, Zhuang J, Liu SJ, Vogel CFA, Rastinejad F, Wu D
Nature communications 2025 Feb 3;16(1):1282

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ARv7 promotes the escape of prostate cancer cells from androgen deprivation therapy-induced senescence by mediating the SKP2/p27 axis.

Zhuang D, Kang J, Luo H, Tian Y, Liu X, Shao C
BMC biology 2025 Feb 28;23(1):66

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A long-lived pool of PINK1 imparts a molecular memory of depolarization-induced activity.

Pollock L, Georgiou IC, Rusilowicz-Jones EV, Clague MJ, Urbé S
Science advances 2025 Feb 28;11(9):eadr1938

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SJB2-043, a USP1 Inhibitor, Suppresses A549 Cell Proliferation, Migration, and EMT via Modulation of PI3K/AKT/mTOR, MAPK, and Wnt Signaling Pathways.

Wu L, Yu M, Liang H, Lin L, Li H, Chen G, Muhetaer H, Li J, Wu B, Jia X, Dang Y, Zheng G, Li C
Current issues in molecular biology 2025 Feb 27;47(3)

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Schisandra chinensis lignans exerts endocannabinoids-like antidepressive effect: The phagocytotic relationship of activated CB2R-mediated M2 microglia and "stressed-but-viable" neuron.

Wang J, Du H, Li M, Yan T, Jia Y
Journal of ethnopharmacology 2025 Feb 27;342:119385

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Network pharmacology alliance with experimental validation unveils the anti-colorectal cancer mechanism of Xianlian Jiedu decoction.

Fan X, Yan Q, Xu W, Chen H, Xu Y, Lu S, Xu C, Tan J, Yu C, Lai Y, Fan M, Tao L, Li L, Shen W, Cheng H, Sun D
Journal of ethnopharmacology 2025 Feb 27;342:119361

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Epigenetic Regulation of ZNF687 by miR-142a-3p and DNA Methylation During Osteoblast Differentiation and Mice Bone Development and Aging.

Varela D, Varela T, Conceição N, Cancela ML
International journal of molecular sciences 2025 Feb 27;26(5)

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Identification of E3 ubiquitin ligase-based molecular subtypes and prognostic signature regarding prognosis and immune landscape in bladder cancer.

Hu B, Zhao T, Li Y, Li K, Shen L, Zhu Q, Ma B, Wei Y
Cancer cell international 2025 Feb 27;25(1):70

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PTPRO represses breast cancer lung metastasis by inhibiting the JAK2-YAP axis.

Xiong X, Liu J, Wu X, Yao Z, Meng Y, Liu S, Chen Y, Ren H, Gao S, Qiu X, Zhang H
Scientific reports 2025 Feb 27;15(1):7065

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TMEM106B deficiency leads to alterations in lipid metabolism and obesity in the TDP-43(Q331K) knock-in mouse model.

Yang C, Lee GB, Hao L, Hu F
Communications biology 2025 Feb 26;8(1):315

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8q24 derived ZNF252P promotes tumorigenesis by driving phase separation to activate c-Myc mediated feedback loop.

Qu T, Zhang C, Lu X, Dai J, He X, Li W, Han L, Yin D, Zhang E
Nature communications 2025 Feb 26;16(1):1986

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RNASEK interacting with PEDV structural proteins facilitates virus entry via clathrin-mediated endocytosis.

Qin W, Kong N, Xie S, Liu H, Yang X, Wang Y, Cao X, Liu Y, Wang J, Sun H, Tong W, Yu H, Zheng H, Zhang W, Tong G, Shan T
Journal of virology 2025 Feb 25;99(2):e0176024

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MA104 cell line is permissive for human bocavirus 1 infection.

Tang J, Chen S, Deng Y, Liu J, Huang D, Fu M, Xue B, Liu C, Wu C, Wang F, Zhou Y, Yang Q, Chen X
Journal of virology 2025 Feb 25;99(2):e0153924

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Tetraspanin CD81 serves as a functional entry factor for porcine circovirus type 2 infection.

Li J, Lv L, Gao Y, Sun Y, Bai J, Wang X, Sun H, Jiang P
Journal of virology 2025 Feb 25;99(2):e0140824

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Nuclear-localized HKDC1 promotes hepatocellular carcinoma through phosphorylating RBBP5 to upregulate H3K4me3.

Ye L, Shen S, Mao Q, Lu H, Liu H, Zhang P, Jiang Z, Ma W, Sun Y, Chu Y, Zhou Z, Liu R, Li J, Li ST, Gao P, Zhang H
Cell reports 2025 Feb 25;44(2):115250

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Targeting pyroptosis reverses KIAA1199-mediated immunotherapy resistance in colorectal cancer.

Li L, Zhao L, Zhou D, Yu Y, Zhang P, Zheng J, Lin Z, Yu D, Ren J, Zhang J, Zhou P, Zhang D, Zhang T
Journal for immunotherapy of cancer 2025 Feb 25;13(2)

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FOXO4-DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53-serine 15 phosphorylation.

Kong YX, Li ZS, Liu YB, Pan B, Fu X, Xiao R, Yan L
Communications biology 2025 Feb 24;8(1):299

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Identification and functional analysis of NPR2 truncating mutations in two Chinese families with short stature.

Wei S, Li R, He D, Zhang C, Zhang M, Li Y, Chen S, Liu F, Ban B, Zhao Q
BMC pediatrics 2025 Feb 24;25(1):130

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RNF167 mediates atypical ubiquitylation and degradation of RLRs via two distinct proteolytic pathways.

He M, Yang Z, Xie L, Chen J, Liu S, Lu L, Li Z, Zheng B, Ye Y, Lin Y, Bu L, Xiao J, Zhong Y, Jia P, Li Q, Liang Y, Guo D, Li CM, Hou P
Nature communications 2025 Feb 24;16(1):1920

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Endosomal trafficking participates in lipid droplet catabolism to maintain lipid homeostasis.

Peng W, Chen S, Ma J, Wei W, Lin N, Xing J, Guo W, Li H, Zhang L, Chan K, Yen A, Zhu G, Yue J
Nature communications 2025 Feb 24;16(1):1917

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Hesperetin-Enhanced Metformin to Alleviate Cognitive Impairment via Gut-Brain Axis in Type 2 Diabetes Rats.

Zhang D, He X, Wang Y, Wang X, Han X, Liu H, Xing Y, Jiang B, Xiu Z, Bao Y, Dong Y
International journal of molecular sciences 2025 Feb 23;26(5)

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The inhibition of ZC3H13 attenuates G2/M arrest and apoptosis by alleviating NABP1 m6A modification in cisplatin-induced acute kidney injury.

Sheng Q, Yu Q, Lu S, Yang M, Fan X, Su H, Kong Z, Gao Y, Wang R, Lv Z
Cellular and molecular life sciences : CMLS 2025 Feb 22;82(1):86

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Chemical Analysis and Antioxidant Activities of Resin Fractions from Pistacia lentiscus L. var. Chia in Neuroblastoma SH-SY5Y Cells.

Georgantopoulos A, Kalousi FD, Pollastro F, Tsialtas I, Kalogiouri NP, Psarra AG
Molecules (Basel, Switzerland) 2025 Feb 21;30(5)

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Succinate supplementation alleviates liver cancer by inhibiting the FN1/SQLE axis-mediated cholesterol biosynthesis.

Chang S, Tomii A, Zhou Y, Yang X, Dong Y, Yan J, Wu A, Wang Y, Zhang Q, Meng H, Yu L, Sun W, Liu D
iScience 2025 Feb 21;28(2):111731

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In vitro analysis of the molecular mechanisms of ursolic acid against ovarian cancer.

Zhang R, Zhang Z, Xie L, Yu Z, Gao R, Zhang ZR, Zhang Y, Wei X, Chen Y, Jiao S, Gao Y, Guo JP
BMC complementary medicine and therapies 2025 Feb 21;25(1):65

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Growth differentiation factor 15 aggravates sepsis-induced cognitive and memory impairments by promoting microglial inflammatory responses and phagocytosis.

Chen L, Luo S, Liu T, Shuai Z, Song Y, Yang Q, Wang Y, Huang H, Luo Y
Journal of neuroinflammation 2025 Feb 21;22(1):44

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Plumbagin improves myocardial fibrosis after myocardial infarction by inhibiting the AKT/mTOR pathway to upregulate autophagy levels.

Guo S, Qi X, Zhang L, Lu K, Li X, Zhu J, Lian F
International immunopharmacology 2025 Feb 20;148:114086

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NINJ1-mediated plasma membrane rupture of pyroptotic endothelial cells exacerbates blood-brain barrier destruction caused by neutrophil extracellular traps in traumatic brain injury.

Zheng XB, Wang X, Gao SQ, Gao CC, Li T, Han YL, Zhao R, Sun Y, Miao SH, Qiu JY, Jin WX, Zhou ML
Cell death discovery 2025 Feb 20;11(1):69

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Metformin inhibits the growth of SCLC cells by inducing autophagy and apoptosis via the suppression of EGFR and AKT signalling.

Xia H, Tai XJ, Cheng W, Wu Y, He D, Wang LF, Liu H, Zhang SY, Sun YT, Liu HZ, Liu DD, Zhao HZ, Ji FY, Li XH
Scientific reports 2025 Feb 19;15(1):6081

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Multi-omics investigation of Porphyromonas gingivalis exacerbating acute kidney injury through the gut-kidney axis.

Dong L, Ji Z, Sun J, Hu J, Jiang Q, Wei W
mSystems 2025 Feb 18;10(2):e0113624

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PBX1 attenuates inflammation and apoptosis of trophoblast cells induced by LPS through downregulating the transcription of TMUB1: PBX1 ameliorates RSA development.

Zhang X, Wang S, Liang L, Hu F, Zhang X, Cui X, Zhang Z, Wu X
Journal of molecular histology 2025 Feb 17;56(2):91

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Integrated multi-omics analysis revealed the molecular networks and potential targets of cellular senescence in Alzheimer's disease.

Xu Y, Liu S, Zhou Z, Qin H, Zhang Y, Zhang G, Ma H, Han X, Liu H, Liu Z
Human molecular genetics 2025 Feb 17;34(5):381-391

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The Gut Microbiota Metabolite Butyrate Modulates Acute Stress-Induced Ferroptosis in the Prefrontal Cortex via the Gut-Brain Axis.

Wang Z, Ma X, Shi W, Zhu W, Feng X, Xin H, Zhang Y, Cong B, Li Y
International journal of molecular sciences 2025 Feb 17;26(4)

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STK11 genetic alterations in metastatic EGFR mutant lung cancer.

Yin D, Lu X, Liang X, Lu Y, Xiong L, Wu P, Wang T, Chen J
Scientific reports 2025 Feb 17;15(1):5729

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α-spinasterol isolated from Achyranthes aspera L. ameliorates inflammation via NF-κB and Nrf2/HO-1 pathways.

Zeng Q, Xiao W, Zhang H, Liu W, Wang X, Li Z, Han Y, Wang Z, Li S, Yang J, Ouyang W
Scientific reports 2025 Feb 17;15(1):5723

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Lipotoxicity-induced upregulation of FIS1 exacerbates mitochondrial fragmentation and promotes NLRP3-dependent pyroptosis in diabetic cardiomyopathy.

Luo L, Wu Q, Xiao Q, Chen Y, Deng Z, Cen C, Lin J
Free radical biology & medicine 2025 Feb 16;228:183-196

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Discovery and optimization of 1,2,4-triazole derivatives as novel ferroptosis inhibitors.

Zhang J, Lin F, Xiao Y, Cen SY, Wan BW, Li X, Zhao Y, He Y, Yuan HX, Nie S
European journal of medicinal chemistry 2025 Feb 15;284:117192

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Treatment of Acute Ulcerative Colitis with Zinc Hyaluronate in Mice.

Zhang L, Fu X, Li J, Xiao W, Xiong X, Lv H, Zhang Z, Ju J
Journal of microbiology and biotechnology 2025 Feb 14;35:e2408050

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Brown Algae Polysaccharides Alleviate Diquat-Induced Oxidative Stress in Piglets and IPEC-J2 Cells via Nrf2/ARE Signaling Pathway.

Hou C, Yu Z, Shi C, Huang Y, Liu H
Animals : an open access journal from MDPI 2025 Feb 14;15(4)

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Matrix stiffness regulates nucleus pulposus cell glycolysis by MRTF-A-dependent mechanotransduction.

Xu H, Wei K, Ni J, Deng X, Wang Y, Xiang T, Song F, Wang Q, Niu Y, Jiang F, Wang J, Sheng L, Dai J
Bone research 2025 Feb 14;13(1):23

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Peripheral Evolution of Tanshinone IIA and Cryptotanshinone for Discovery of a Potent and Specific NLRP3 Inflammasome Inhibitor.

Zhu W, Bao X, Yang Y, Xing M, Xiong S, Chen S, Zhong Y, Hu X, Lu Q, Wang K, Ling Q, Cui S
Journal of medicinal chemistry 2025 Feb 13;68(3):3460-3479

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Mechanism of Ca(2+) overload caused by STIM1/ORAI1 activation of store-operated Ca(2+) entry (SOCE) in hydrogen peroxide-induced mitochondrial damage and apoptosis in human primary melanocytes.

Li Z, Yu Y, Cao X, Wang Y, Lu J, Feng Y, Jiang Y, Lu Y
Molecular biology reports 2025 Feb 12;52(1):223

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Antitumor Activity of USP7 Inhibitor GNE-6776 in Non-Small Cell Lung Cancer Involves Regulation of Epithelial-Mesenchymal Transition, Cell Cycle, Wnt/β-Catenin, and PI3K/AKT/mTOR Pathways.

Wu L, Lin L, Yu M, Li H, Dang Y, Liang H, Chen G, Muhetaer H, Zheng G, Li J, Jia X, Wu B, Li C
Pharmaceuticals (Basel, Switzerland) 2025 Feb 12;18(2)

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Interleukin-1 prevents SARS-CoV-2-induced membrane fusion to restrict viral transmission via induction of actin bundles.

Zheng X, Yu S, Zhou Y, Yu K, Gao Y, Chen M, Duan D, Li Y, Cui X, Mou J, Yang Y, Wang X, Chen M, Jiu Y, Zhao J, Meng G
eLife 2025 Feb 12;13

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Mettl3/Eed/Ythdc1 regulatory axis controls endometrial receptivity and function.

Hu X, Li J, Ding C, Jiang J, Xia W, Lu J, Su H, Zhang M, Li H, Liu JL, Lin Y, Meng Q, Huang B
Communications biology 2025 Feb 11;8(1):215

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Cumulative experience meets modern science: Remarkable effects of TongXieYaoFang formula on facilitating intestinal mucosal healing and secretory function.

Du X, Liu L, Yang L, Zhang Y, Dong K, Li Y, Chen Y, Yang Q, Zhu X, Li Q
Journal of ethnopharmacology 2025 Feb 11;341:119370

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β-elemene, a sesquiterpene constituent from Curcuma phaeocaulis inhibits the development of endometriosis by inducing ferroptosis via the MAPK and STAT3 signaling pathways.

Fu Z, Liu H, Kuang Y, Yang J, Luo M, Cao L, Zheng W
Journal of ethnopharmacology 2025 Feb 11;341:119344

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Jiawei Ermiao Granules (JWEMGs) clear persistent HR-HPV infection though improving vaginal microecology.

Li X, Ning L, Zhao H, Gu C, Han Y, Xu W, Si Y, Xu Y, Wang R, Ren Q
Journal of ethnopharmacology 2025 Feb 11;341:119342

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Glycyrrhiza uralensis Fisch. Attenuates Dioscorea bulbifera L.-induced liver injury by regulating the FXR/Nrf2-BAs-related proteins and intestinal microbiota.

Wang X, Zhang Y, Shi L, Zhu H, Shangguan H, Ding L, Zhang D, Deng C, Liu J, Xie Y
Journal of ethnopharmacology 2025 Feb 11;341:119319

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Multi-omics analysis reveals the impact of YAP/TEAD4-mediated EIF5A1 expression on mitochondrial apoptosis and bladder cancer progression.

Li KP, Wan S, Wang CY, Chen SY, Wang L, Liu SH, Yang L
BMC cancer 2025 Feb 11;25(1):234

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A novel defined risk signature of ferroptosis-related lncRNAs for predicting prognosis, immune infiltration, and chemotherapy response in multiple myeloma.

Yu W, Jing Z, Tang J, Chen J
Discover oncology 2025 Feb 11;16(1):160

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FTO-associated osteoclastogenesis promotes alveolar bone resorption in apical periodontitis male rat via the HK1/USP14/RANK pathway.

Qian Y, Wu J, Yang W, Lyu R, You Q, Li J, He Q, Zhuang Y, Wang W, Wang Y, Zhu Y, Wu Z, Chen D
Nature communications 2025 Feb 11;16(1):1519

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LncRNA NR_045147 modulates osteogenic differentiation and migration in PDLSCs via ITGB3BP degradation and mitochondrial dysfunction.

Long L, Zhang C, He Z, Liu O, Yang H, Fan Z
Stem cells translational medicine 2025 Feb 11;14(2)

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Delivery of FBXO6 with highly branched poly(β-amino ester)s to modulate the inflammatory environment for the treatment of osteoarthritis.

Shi Y, Shen S, Huang D, Yilamu K, Chen Z, Wang K, Chen P, Pan N, Jin Z, Guo L, Xu W, Zhao X
Journal of controlled release : official journal of the Controlled Release Society 2025 Feb 10;378:294-305

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Euphorbia helioscopia L. inhibits lung tumorigenesis through alleviating exhausted T cell induced by chronic inflammation.

Duan W, Zhou Z, Huang Y, Cui Y, Jin X, Liu R, Chen L
Journal of ethnopharmacology 2025 Feb 10;338(Pt 2):119097

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New idea of Fuke Qianjin capsule in treating sequelae of pelvic inflammatory disease: Anti-inflammatory in the early stage and reparative in the later stage.

Xu C, Yi M, Xiao Z, Xiang F, Wu M, Zhang Z, Zheng Y, Gong Y, Li Y, Su L, Liao Y, Zhang P, Xia B, Liao D, Lin L
Journal of ethnopharmacology 2025 Feb 10;338(Pt 2):119066

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Chronic treatment of mixture of two iridoids proportional to prescriptional dose of Yueju improves hippocampal PACAP-related neuroinflammation and neuroplasticity signaling in the LPS-induced depression model.

Wu Z, Yin Y, Liu R, Li X, Wang Z, Wu C, Tan J, Fu Z, Song C, Lee Wong N, Peng X, Lai S, Cui J, Han M, Peng Y, Sun Y, Wu L, Adzic M, Zeng L, Zhang H, Yau SY, Chen G
Journal of ethnopharmacology 2025 Feb 10;338(Pt 2):119031

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Dengzhan Shengmai capsule ameliorates cognitive impairment via inhibiting ER stress in APP/PS1 mice.

Ma HH, Zheng JY, Qiu YH, Su S, Lu FM, Wu GL, Zhang SJ, Cai YF
Journal of ethnopharmacology 2025 Feb 10;338(Pt 1):119016

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Transcription factor XBP1s promotes endometritis-induced epithelial-mesenchymal transition by targeting MAP3K2, a key gene in the MAPK/ERK pathway.

Gao K, Si M, Qin X, Zhang B, Wang Z, Lin P, Chen H, Wang A, Jin Y
Cell communication and signaling : CCS 2025 Feb 10;23(1):72

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Combinational Inhibition of MEK and AKT Synergistically Induces Melanoma Stem Cell Apoptosis and Blocks NRAS Tumor Growth.

Alobaidi R, Islam N, Olkey T, Haribabu Y, Shamo M, Sykora P, Simbulan-Rosenthal CM, Rosenthal DS
Cells 2025 Feb 10;14(4)

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HDAC1-3 inhibition triggers NEDD4-mediated CCR2 downregulation and attenuates immunosuppression in myeloid-derived suppressor cells.

Xie Z, Shao J, Shen Z, Ye Z, Okada Y, Okuzaki D, Okada N, Tachibana M
Cancer immunology, immunotherapy : CII 2025 Feb 1;74(3):81

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MDPAO1 peptide from human milk enhances brown adipose tissue thermogenesis and mitigates obesity.

Gao Y, Zhang J, Cao M, Zhang Y, Cao M, Gu W, Wang M
Molecular and cellular endocrinology 2025 Feb 1;597:112443

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Low shear stress induces vascular endothelial cells apoptosis via miR-330 /SOD2 /HSP70 signaling pathway.

Li K, Wang S, Li J, Wang L, Zhang Q, Hou L, Yu X, Liu Z, Lv T, Shang L
Experimental cell research 2025 Feb 1;445(1):114410

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IGSF8 impairs migration and invasion of trophoblast cells and angiogenesis in preeclampsia.

Chu X, Chen X, Guo M, Li X, Qu Z, Li P
Experimental cell research 2025 Feb 1;445(1):114405

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Integrated network pharmacology, bioinformatics, and experiment analysis to decipher the molecular mechanism of Salidroside on Gastric cancer via targeting NCOA4-mediated ferritinophagy.

Fu Y, Huang G, Cai Y, Ren M, Cheng R, Chai Y, Wang Y, An Y, Yan T, Zhu L, Liu X
Chemico-biological interactions 2025 Feb 1;407:111368

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Long-term glucosamine supplementation aggravates atrial fibrillation susceptibility by impairing AMPK signaling.

Qin X, Gong H, Jin L, Wang Y, Dang K, Li H, Zheng Q
Life sciences 2025 Feb 1;362:123380

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Carboxymethyl chitosan and sodium alginate oxide pH-sensitive dual-release hydrogel for diabetes wound healing: The combination of astilbin liposomes and diclofenac sodium.

Wu X, Wang Y, Liu X, Ding Q, Zhang S, Wang Y, Chai G, Tang Y, Yang J, Yu T, Liu W, Ding C
Carbohydrate polymers 2025 Feb 1;349(Pt B):122960

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CircRNA circACTN4 Promotes the Progression of Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma by Targeting the miR-424-5p/NCAPG/Wnt Axis.

Shan J, Pu J, Chen X, Zhang Y, Li J, Qin L, Shi J, Zhou L, Deng Y
Clinical and experimental medicine 2025 Feb 1;25(1):47

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Zinc ions facilitate metabolic bioenergetic recovery post spinal cord injury by activating microglial mitophagy through the STAT3-FOXO3a-SOD2 pathway.

Cui Y, Bai M, Gao S, Zhao H, Mei X
Free radical biology & medicine 2025 Feb 1;227:64-79

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Strontium-Alix interaction enhances exosomal miRNA selectively loading in synovial MSCs for temporomandibular joint osteoarthritis treatment.

Yuan W, Liu J, Zhang Z, Ye C, Zhou X, Yi Y, Wu Y, Li Y, Zhang Q, Xiong X, Xiao H, Liu J, Wang J
International journal of oral science 2025 Feb 1;17(1):6

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Nuclear factor E2 related factor 2 may alleviate liver injury by regulating iron overload and lipid peroxidation induced by chronic fluorosis.

Xiao X, Tu X, Wei N, He WW, Zeng XX, Liao W, Deng J, Dong YT, Qi XL, Xiao Y, Hong W, He Y, Lou DD, Guan ZZ
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2025 Dec;92:127775

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Phosphorylation-Mediated Regulation of FBXO31 Stability Under Cellular Homeostasis.

Chen L, Mo J, Liu J, Lv L
Advanced biology 2025 Dec;9(12):e00017

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5-Methoxytryptophan attenuates hypobaric hypoxia induced acute lung injury by alleviating lipid peroxidation via targeting peroxiredoxin 6.

Lai X, Wan X, Bao X, Yang Q, Zhang W, Tan Y, Cai X, Wang Z, Li Y, Liu C, Deng Z, Zheng P, Tian D, Chen M, Yin H, Xu G, Huang Q, Zhang Z, Xia H, Deng F
Redox biology 2025 Dec;88:103922

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Targeting aerobic glycolysis by quercetin inhibits acute monocytic leukemia SHI-1 cells.

Liu Y, Lv K, Gao R, Yu X, Ni R, Lan J, Wang B, Zhao Y
Annals of medicine and surgery (2012) 2025 Dec;87(12):8266-8275

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WTAP-induced m(6)A Methylation of Atoh8 Promotes Cell Proliferation and Fibrosis in Diabetic Nephropathy.

Wang S, Zhang H, Fei B, Zhang M
Cell biochemistry and biophysics 2025 Dec;83(4):4453-4463

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In vitro Comparison of Cytotoxicity and Osteoclastogenesis of Four Bioceramic Sealers in Murine Bone Marrow Cells.

Chen Z, Sun X, Wang Z, Chang Z, Zhu L, Wang L
International dental journal 2025 Dec;75(6):103959

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Comparative Evaluation of Biocompatibility between Conventional and Computer-Aided Design/Computer-Aided Manufacturing Dental Polymers Using a Golden Hamster Model.

Wei X, Shangguan H, Wu L, Gao L, Pan Y, Cheng Y, Cheng H, Wang Y
International dental journal 2025 Dec;75(6):103958

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C1QBP Drives M2 Macrophage Polarization Via TRAF2-CCL2 to Promote Oral Squamous Cell Carcinoma Progression.

Qin X, Kang K, Zhu B, Shi Y, Bu S
International dental journal 2025 Dec;75(6):103938

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High-Glucose Microenvironment Accelerates Malignant Progression Via O-GlcNAcylation in Oral Squamous Cell Carcinoma.

Zhu Z, Ren W, Yan X, Li S, Zheng J, Zhi K, Gao L
International dental journal 2025 Dec;75(6):103897

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Haploinsufficiency of brain-specific kinase BRSK1 causes epilepsy and neurodevelopmental disorders.

Zhang Q, Yamanaka H, Li P, Li Y, Luo T, Xia M, Liu T, Liu X, Lu Q, Yang B, He F, Du K, Shu Y, Peng B, Jiang YH, Wang Y
Epilepsia 2025 Dec;66(12):5033-5054

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Determination of FAT-1 desaturase activity and substrate preference.

Xu X, Wang Y, Xu Y, Yao Y, Fu L, He S, Leng J, Lu Q, Zou X, Liang B
Journal of lipid research 2025 Dec;66(12):100945

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AKR1B1 is Required for Maintaining Acute Leukemia Cell Survival by Epigenetic Silencing of Tumor Suppressor Genes.

Chen J, Xu L, Li W, Sun M, Chen Y, Qiu T, Wu Y, Lv X, Liu F, Fan H
Biochemical genetics 2025 Dec;63(6):5273-5293

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Indirubin regulates M1/M2 polarization and inhibits ferroptosis in dextran sulfate sodium induced colitis and in cultured THP-1 cells.

Huang YX, Zhang JR, Fu SH, Liu Z, Zhong HJ, Zhong QY, Luo YD, Hu YJ, Zhu HP, Wen B, Chen S
Pharmaceutical biology 2025 Dec;63(1):698-715

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Thermoradiotherapy reverses proliferation, metastasis, and anoikis resistance in glioblastoma through ITGA5-PI3K/AKT axis.

Shi Y, An H, Wang W, Nan D, Cui Y, He M, Lian J, Zhang X, Peng J, Yang X, Liu P
Translational oncology 2025 Dec;62:102552

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Porphyromonas gingivalis Induces Endothelial Dysfunction Through Sirt3-Dependent CypD Acetylation.

Xu S, Zheng C, Huang J, Lu B, Que H, Xu L, Hou Y, He L, Fan X, Deng K, Hu R, Deng H, Wang Y
Journal of periodontal research 2025 Dec;60(12):1296-1307

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Identification of Cathepsin H and Metabolic Traits as Potential Biomarkers for Lung Cancer by Mendelian Randomization and Single-Cell Transcriptomics.

Song C, Liu W, He Z, Liu J, Wang R, Wu L, Wang Y, Zheng M, Tian D, Mao W
Advanced genetics (Hoboken, N.J.) 2025 Dec;6(4):e00012

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Yin Yang 1 Promotes Antiprogrammed Cell Death-1 Resistance in Hepatocellular Carcinoma through Polypeptide N-Acetylgalactosaminyltransferase 16-Mediated Glycosylation of Programmed Death Ligand-1.

Lin SS, Xiao G, Liu QQ, Xue JH, Chen ZJ, Zhang HH, Zhu XP, Huang KL, Yang CN, Zhu K, Lin HM, Zhang R
MedComm 2025 Dec;6(12):e70504

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Fuzheng Huayu recipe inhibits alveolar macrophage M2 polarization and oxidative phosphorylation via METTL3-mediated NDUFA2 m6A modification.

Sun Y, Yuan X, Huang W, Li Q, Zhang S, Hang Y, Huang J, Li J, Qian Y, Zhang W, Li L
Journal of bioenergetics and biomembranes 2025 Dec;57(6):453-467

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Qing-Re-Xiao-Zheng-yi-qi formula protects renal function by stabilizing lysosomal membranes and inhibiting NLRP3-inflammasome-mediated pyroptosis in diabetic kidney disease.

Tian L, Wang L, Wang Y, Liu W, Zhao W, Wang Y
Annals of medicine 2025 Dec;57(1):2581157

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Diagnostic PANoptosis-related genes in acute kidney injury: bioinformatics, machine learning, and validation.

Chen Z, Wang X, Shao Y, Wang K, Xue D
Annals of medicine 2025 Dec;57(1):2553930

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Anoikis-related genes predicts prognosis and therapeutic response in renal cell carcinoma.

Zhou L, Lu H, Fu B, Fu J
Annals of medicine 2025 Dec;57(1):2548042

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Calycosin attenuates mitochondrial damage and pyroptosis in heart failure via the Nrf2/ROS/TXNIP pathway.

Yuan HJ, Han QC, Yu YD, Yu H, Liu XJ, Xue YT, Li Y
International journal of molecular medicine 2025 Dec;56(6)

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Bioengineering an improved three-dimensional vascularized co-culture model for studying Neuron-Microglia interactions.

Han Y, Guo L, Wang M, Cao Z, Zheng X, Wang X, Jin L, Wei X, Wang X, Zhao J
Bioactive materials 2025 Dec;54:813-828

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KNC nanozyme repairs hypoxia ischemia brain damage through ALOX12 mediated lipid peroxidation inhibition.

Dong X, Jiang D, Chen S, Tan J, Zhao J, Liu X, Lu Z, Yeung KWK, Liao Y, Liu X, Ouyang L
Bioactive materials 2025 Dec;54:531-548

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Integrated Analysis of Single-Cell and Transcriptome Data Reveals the Role and Regulatory Mechanisms of Neuroinflammation in Parkinson's Disease.

Geng Y, Wang RY, Dong MY, Qian YL, Wang XH, Xia WW, Shen Y, Zhang KZ
Inflammation 2025 Dec;48(6):3986-4005

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A novel β-carboline alkaloid derivative targeting MDM2-p53 pathway suppresses colorectal cancer progression.

Zeng F, Chen C, Fu Z, Huang H, Cui W, Zhou Y, Kong Y, Liu X, Xu Z, Wang S, Xiao T, Xia H
Cellular oncology (Dordrecht, Netherlands) 2025 Dec;48(6):1821-1836

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Unraveling the miR-144-3p/PUMA pathway: a novel regulator of FDX1-mediated cuproptosis in colorectal cancer.

Jia G, Li J, Jiang M, Liu N, Ding N, Jiang X, Zhang G, Tan X, Kang Y, Zhang L, Wang F, Zhang Y
Cellular oncology (Dordrecht, Netherlands) 2025 Dec;48(6):1693-1710

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Irisin targets the HK1-glycolysis-NLRP3 pyroptosis axis to prevent chronic kidney disease-associated vascular calcification.

Xu W, Wang P, Zhu X, Zhang Z, Dong X, An R, Pang Q, Zhang A
Renal failure 2025 Dec;47(1):2610545

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Zhenwu decoction ameliorates adriamycin-induced nephrotic syndrome in rats via dual modulation of AVP-V2R-AQP2 and RAAS-MR-AQP3 pathways.

Xu M, Du M, Qu W, Wei Y, Wang H, Yang X
Renal failure 2025 Dec;47(1):2599570

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Arfgef3 knockout ameliorates ischemia reperfusion-induced acute kidney injury via mitochondrial dysfunction alleviation in mice.

Wang L, Yao L, Xie D, Ding W
Renal failure 2025 Dec;47(1):2572359

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Glycyrrhizin alleviates contrast-induced acute kidney injury via inhibiting HMGB1-mediated renal tubular epithelial cells ferroptosis.

Tian FY, Liu K, Tang ZY, Zhou G, Zhou GL, Chen RF, Liu HB, Fang WJ, Zuo XC, Zhou LY
Renal failure 2025 Dec;47(1):2548613

---

Analysis of potential targets of 20S-protopanaxadiol on diabetic nephropathy based on network pharmacology, molecular docking, and experimental validation.

Li C, Ma C, Zhao R, Li X, Yu H, Yuan M
Renal failure 2025 Dec;47(1):2526688

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METTL3 alleviates renal tubular mitochondrial dysfunction by regulating the TUG1/PGC-1a axis in an IGF2BP2-dependent manner in diabetic nephropathy.

Chen T, Wang J, Xu Y, Zhu Y, Jin Y, Fan Q
Renal failure 2025 Dec;47(1):2521455

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Association between Lyn tyrosine kinase and renal injury in patients with systemic lupus erythematosus.

Sun J, Gu Y, Lin W, Luo L, Li W, He J, Zhan Z, Tang J
Renal failure 2025 Dec;47(1):2515532

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Dihydromyricetin protects against cisplatin-induced renal injury and mitochondria-mediated apoptosis via the EGFR/HSP27/STAT3 signaling pathway.

Xu Z, Zhang M, Zhang X, Han H, Ye W, Chen Z, Lv Z, Liu Y, Liu Z, Gong J, Zhu B, Zhou S, Zhu R, Tao C, Zhang G, Yan X
Renal failure 2025 Dec;47(1):2490202

---

Circ-0069561 as a novel diagnostic biomarker for progression of diabetic kidney disease.

Chen C, Liu X, Zhu S, Wang Y, Ma Y, Hu Z, Wu Y, Jiang L
Renal failure 2025 Dec;47(1):2490200

---

Proteomics reveals the key transcription-related factors mediating obstructive nephropathy in pediatric patients and mice.

Cao H, Tao Y, Jin R, Li P, Zhou H, Cheng J
Renal failure 2025 Dec;47(1):2443032

---

SIRT5 Facilitates Liver Steatosis Progression via Promoting SDH Desuccinylation During High-Fat Diet Feeding.

Liu Z, Hu J, Lin Y, Ge C, Shao Y, Bao M, Liu M, Jia S, Li Y, Xu X, Li R, Jiang Q, Yan F, Xiao F, Ye J
Liver international : official journal of the International Association for the Study of the Liver 2025 Dec;45(12):e70433

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The deubiquitinase OTUD1 orchestrates cisplatin chemosensitivity of non-small cell lung cancer through destabilizing RAD23B/XPC.

Wu Z, Wang M, Dong X, Sun Y, Zhang L, Tang M, Jiang X, Guo Y, Wang J, Wang W, Yuan Z, Mi Z
Oncogene 2025 Dec;44(50):4855-4867

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HOXA7 can be used for prognostic evaluation and molecular targeted therapy of gliomas: a multidimensional study based on a large sample size.

Sha Z, Liu Z, Gao Y
Biochemistry and biophysics reports 2025 Dec;44:102279

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Chinese traditional medicine complex hemorrhoidal analgesic cream promotes wound healing in diabetic rats after anal fistula surgery via Keap1/Nrf2 signaling pathway.

Liu J, Yin Z, Tian X, Liu D, Wang C, Yuan H
Biochemistry and biophysics reports 2025 Dec;44:102258

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Varespladib Alleviates Colonic Inflammation Induced by High-Fat Diet via Downregulating the TGF-β/Smad Pathway and AA Pathway by Inhibiting sPLA(2).

Shirui M, Yuanyuan L, Linfeng W, Jiahao L, Daixuan Z, Ying X, Chunhong H
Journal of gastroenterology and hepatology 2025 Dec;40(12):2933-2943

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Design, synthesis, and bioevaluation of pyrazole-containing tubulin polymerisation inhibitors based on conformational constraint strategy.

Sun Z, Wang J, Li F, Huang L, Zheng S, Guan Q, Wang Z, Zhang W
Journal of enzyme inhibition and medicinal chemistry 2025 Dec;40(1):2545004

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Suvorexant attenuates cognitive impairment associated with circadian rhythm sleep-wake disorders by modulating microglia activation via the BMAL1/NLRP3 pathway.

Hu Y, Yun T, Hou D, Yang G
Experimental neurology 2025 Dec;394:115464

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Lentiviral Gene Delivery Rescues Ciliary Defects in Patient-Derived Airway Organoids from Primary Ciliary Dyskinesia.

Huo C, Luo T, Wu L, Yang F, Xu Z, Tao X, Xia J, Zhou T, Jiang Y, Xie S
Human gene therapy 2025 Dec;36(23-24):1481-1492

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3D printing combined with thermally induced phase separation for engineering hierarchical osteogenic PLA scaffolds.

Yun X, Li Z, Yan Z, Li S, Dai Z, Hu J, Ren Y, Huang L, Wang Q, Zhang C, Li J, Deng C, Liu H, Zheng W, Zhong C, Zhang Z
Materials today. Bio 2025 Dec;35:102621

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Bioinspired honeycomb-mimetic adaptive hyaluronic acid hydrogel composite scaffold: intelligent prevention and treatment of infection of bone implants and promotion of bone repair.

Fu J, Lan H, Liu L, Zou L, Huan X, Liu C, Wu Y, Chen H, Xi H, Huang Y, Jiang X, Sun G, Liu X, Li D
Materials today. Bio 2025 Dec;35:102558

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4'-hydroxychalcone nanofiber hydrogel dressing promotes diabetic chronic wound healing by regulating macrophage polarization via the TLR/IL-17/TNF signaling pathway.

Li HY, Li MY, Cui CX, Yu HM, Sun Y, Yang JJ, Li YR, Li YQ, Liu TM
Materials today. Bio 2025 Dec;35:102474

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TLyp-1-modified exosome-mediated delivery of circRAPGEF5 ASO inhibits lung adenocarcinoma metastasis via regulating the miR-570-3p/SPP1 axis.

Hu T, Zhou C, Chen Y, Fu J, Dai Y, Ling L, Chen Y, Lu Y, He Y, Chen J, Wang Y
Materials today. Bio 2025 Dec;35:102416

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Molybdenum disulfide induces growth inhibition and autophagy-dependent hepatocyte cell death through directly binding and regulating the activity of MST2.

Qi Z, Yan Y, Xu Z, Chong W, Qiu Y, Huang X, Jing J, Fan H, Liang Q, Liu S, Yan L, Li L, Gao M
Materials today. Bio 2025 Dec;35:102394

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Biomolecule-tailored chiral nickel oxide nanozymes amplify autophagy-mediated tumor ablation via synergistic photodynamic-chemodynamic therapy.

Pang W, Shao Y, Xu H, Li T, Wu L, Liu Z, Zhang L, Chen W, Li Y, Xu D, Cheng J, Xu X
Materials today. Bio 2025 Dec;35:102303

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Reshaping tumor immune microenvironment through ROS-responsive prodrug polyplexes via synergistic effect of CRISPRi system and epigenetic inhibitor for breast cancer therapy.

Deng H, Li Q, Wang B, Yu H, Sun S, Li Z, Pan W, Zhao Q, Dai H, Lu J, Fan L, Tan S
Materials today. Bio 2025 Dec;35:102285

---

Engineered BMSC-derived exosomes deliver miR-17-5p inhibitor to restore sensory conduction via the IL-11/GP130/STAT3/GAP-43 axis in dorsal column lesion.

Wang Z, Zhang M, Wang F, Wang X, Song X, Wang X, Zhang L, Ren L, Jing X, Yang L, Wang T
International journal of biological macromolecules 2025 Dec;334(Pt 1):148958

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Structural characterisation of a polysaccharide from Sanghuangporus vaninii and its synergistic anti-hepatocellular carcinoma activity in combination with sorafenib.

Li J, Shi M, Jia B, Liu S, Zhao Y
International journal of biological macromolecules 2025 Dec;334(Pt 1):148778

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Programmed death-ligand 1 mediates triple-negative breast cancer metastasis and stemness through ten-eleven translocation 3.

Xu Y, Wang J, Gao Y, Li J, Ma Y, Sun C, Tian Z, Dong J, Li P, Lv L
International journal of biological macromolecules 2025 Dec;333(Pt 1):148791

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CircRAB23 functions as miR-532-3p sponge to promote the malignant proliferation and metastasis of intrahepatic cholangiocarcinoma through HMGA2-EMT axis.

Zhang K, Chen J, Shen S, Zhang H, Xia J, Zhao Y, Yang P, Yan X, Liu C, Ge R, Wang N, Yang X
International journal of biological macromolecules 2025 Dec;332(Pt 2):148685

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Acute carbon monoxide poisoning induces renal inflammation and apoptosis via CCL4 upregulation and activation of the PI3K/Akt pathway in mice.

Ni Y, Jiang X, Wang S, Pu T, Yan T, Yu A, Liu Q
Molecular medicine reports 2025 Dec;32(6)

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LncPrep + 96 kb Inhibits the Secretion of Inhibin B in Ovarian Granulosa Cells Through Regulating Endothelial Differentiation-Associated Factor 1.

Zhang H, Liu J, Mou C, Tang Y, Lv Y
Reproductive sciences (Thousand Oaks, Calif.) 2025 Dec;32(12):4003-4014

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MARCH8/NSUN6/ROS-mediated DNA damage positive feedback loop regulates cisplatin resistance in osteosarcoma.

He M, Li T, Wang A, Liu Y, Wang X, Liu Z, Xie J, Wang Y, Wang Y, Ren Z, Ge S, Yang L, Yuan Y
Cell death and differentiation 2025 Dec;32(12):2412-2426

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A novel Gaussia luciferase immunoprecipitation assay for the detection of Getah virus antibodies in pigs.

Li C, Zhang L, Guo J, Tian T, Tang C, Wei Z, Li Y
Veterinary journal (London, England : 1997) 2025 Dec;314:106450

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ASFV activates STAT3 to induce proviral M2 macrophage polarization.

Chen Y, Chen H, Zhang W, Lv P, Wang Z, Liao H, Wei K, He Q, Cui M
Veterinary microbiology 2025 Dec;311:110733

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Transglutaminase-2 Promotes Microglial Synaptic Phagocytosis and Ameliorates Epileptic Seizures by Inhibiting ABCA1 Ubiquitination.

Zhou Z, Wang X, Yang J, Qin J, Feng B, Qin Q, Tian J, Luo Z, Yang X, Huang H, Xu X, Li J, Xu Z, Yu C, Zhang H
CNS neuroscience & therapeutics 2025 Dec;31(12):e70725

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High Shear Stress-Induced Endothelial Piezo1 Downregulation Promotes Intracranial Aneurysm Formation via the PDGF-BB/PDGFRβ Paracrine Signaling Pathway.

Lu Z, Li S, Xu F, Tang H, Zhu S, Wang C, Yang X, Huang Q
CNS neuroscience & therapeutics 2025 Dec;31(12):e70715

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DL-3-n-Butylphthalide Protects Mitochondria Against Ischemia/Hypoxia Damage via Suppressing GCN5L1-Mediated Drp1 Acetylation in Neurons and Mouse Brains.

Zhang H, Zhang N, Yang X, Zhang J, Ge X, Wang L, Wang S, Wen Y
CNS neuroscience & therapeutics 2025 Dec;31(12):e70682

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The m6A reader YTHDF1 facilitates nasopharyngeal carcinoma proliferation and migration via c-MYC.

Han P, Xiao Z, Xia T, Wu T, Li S, Ye Y, Zeng H, Zeng M, Zhong Q, Huang X
The Journal of biological chemistry 2025 Dec;301(12):110833

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Hyperactivity of subicular parvalbumin interneurons drives early amyloid pathology and cognitive deficits in Alzheimer's disease.

Chen YB, Jiang B, Zhuang K, Wang H, Peng HM, Zhong BW, Xie WT, Chen KW, Zou TT, Wang Y, Yang HL, Yang Q, Zhou J, Zhong L, Zhang LH, Zhang J
Molecular psychiatry 2025 Dec;30(12):5777-5789

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FASN regulates CSE-induced apoptosis, oxidative stress and mitochondrial damage in type 2 alveolar epithelial cells by regulating NRF2 expression and nuclear translocation.

Yang K, Zhu G, Peng T, Cheng Y, Guo X
Redox report : communications in free radical research 2025 Dec;30(1):2550412

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Neutrophil extracellular traps drive osteoporosis via NCF2-dependent signaling: integrated transcriptomics with mechanistic validation.

Guo X, Wang L, Chen S, Sun C, Qin J, Liu Q, Gan Y, Li Y, Jin Z, Wei X, Zhang Y
Redox report : communications in free radical research 2025 Dec;30(1):2534745

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Identification of RUVBL2 as a novel biomarker to predict the prognosis and drug sensitivity in multiple myeloma based on ferroptosis genes.

Tang S, Long X, Li F, Jiang S, Fu Y, Liu J
Hematology (Amsterdam, Netherlands) 2025 Dec;30(1):2467499

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Ligand-receptor interactions of V-domain Ig-containing suppressor of T cell activation and programmed death-1 suppress the anticancer activities of T cells.

Abooali M, Lei X, Yasinska IM, Schlichtner S, Hussain R, Siligardi G, Gianga TM, Berger SM, Cholewa D, Gibbs BF, Fasler-Kan E, Sumbayev VV
Immuno-oncology technology 2025 Dec;28:101533

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Deoxycholic Acid and Lipoteichoic Acid cooperatively drive macrophage M2/M1 polarization via TGR5/STAT3 and TLR2/NF-κB to fuel HCC progression in obesity.

Wu J, Zheng W, Ding XZ, Jin QP, Ding MX
Metabolism open 2025 Dec;28:100420

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Lenvatinib promotes hepatocellular carcinoma pyroptosis by regulating GSDME palmitoylation.

Yuan Y, Wang MR, Ding Y, Lin Y, Xu TT, He XX, Li PY
Cancer biology & therapy 2025 Dec;26(1):2532217

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Inhibitory effect of Endostar on HIF-1 with upregulation of MHC-I in lung cancer cells.

Zhao MZ, Zheng HF, Wang JN, Zhang YM, Wang HJ, Zhao ZW
Cancer biology & therapy 2025 Dec;26(1):2508535

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Daurisoline inhibits glycolysis of lung cancer by targeting the AKT-HK2 axis.

Tan SM, Luo L, He YF, Li W, Wan XX
Cancer biology & therapy 2025 Dec;26(1):2442556

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CRIP1 exacerbates osteoarthritis progression by recruiting UBE3A to induce the ubiquitination-mediated degradation of MFGE8.

Li Y, Cheng C, Li M, Hou Y, Li J, Duan S, Gao E, Liu K, Dai Z
Biochemical pharmacology 2025 Dec;242(Pt 4):117407

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The MyD88 inhibitor TJ-M2010-5 protects against obesity in mice by suppressing macrophage-induced metabolic inflammation.

Yang X, Liang FR, Wu YC, Meng FC, Wang HY, Hou L, Zhou P, Zhang C, Luo XP
Biochemical pharmacology 2025 Dec;242(Pt 4):117378

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piR-hsa-35410 promotes triple-negative breast cancer progression via enhancing PFKL mediated glycolysis.

Zhang X, Wang X, Lu J, Zeng L, Xu B, Wang C, Wang Z, Zhou P
Biochemical pharmacology 2025 Dec;242(Pt 2):117337

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Bavachinin exerts anti-tumor effects by activating TLR4/STING axis-dependent PANoptosis and synergistically enhances chemosensitivity in endometrial cancer.

Shu W, Chen G, Zhang J, Dong K, Zhou T, Cheng S, Zhang T, Zhang J, Li H, Yao Y, Yu S, Liu Y, Zhou X, Shen X, Wang H
Biochemical pharmacology 2025 Dec;242(Pt 2):117321

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Exendin-4 Prevents oxLDL-Induced upregulation of TREM2 and attenuates foam cell formation and inflammation in Macrophages.

Wang X, Jiang M, Bao H, Huang R, Chen B, Wu C, Wang H, Luo Z, Li W
Biochemical pharmacology 2025 Dec;242(Pt 2):117306

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A novel covalent inhibitor alleviates type 2 diabetes mellitus by restraining GSK-3β.

Zhang S, Zhao F, Pan C, Wang Y, Yang Z, Yang J, Meng Y, Lv S, Huang J, Dong L, Li L, Dong Y
Biochemical pharmacology 2025 Dec;242(Pt 2):117205

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AMPK regulates the anti-pulmonary fibrosis effects of tracheloside.

Li S, Qian R, Xie W, Lin M, Huang X, Deng L, Xiong D, Liu W, Tang S
Chinese journal of natural medicines 2025 Dec;23(12):100005

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Co-fermentation of honeysuckle-Cassia seeds by Lactobacillus acidophilus and Bacillus subtilis: A new approach to attenuate alcohol-induced acute gastric mucosal damage and modulate immune response.

Zhou M, Cao X, Ji H, Liu Z, Guo H, Zhang Y, Huang Y, Wang F, Pang M, Wei Y
Food research international (Ottawa, Ont.) 2025 Dec;222(Pt 1):117639

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Molecular insights into α-Lactalbumin-Chlorogenic acid interaction: Peptide design and anti-inflammatory mechanisms.

Zheng S, Han C, Zhang T, Zeng X, Bao W, Pan D, Tu M, Wu Z
Food research international (Ottawa, Ont.) 2025 Dec;221(Pt 2):117365

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Pp6-Pfkfb1 axis modulates intracellular bacterial proliferation by orchestrating host-pathogen metabolic crosstalk.

Fan L, Sun Y, Lou F, Fang Z, Ding W, Li X, Li Y, Shen Q, Deng S, Liang J, Zhang F, Tang S, Wang Z, Cai X, Tong J, Xu Z, Zou J, Yang Q, Wang H
PLoS pathogens 2025 Dec;21(12):e1013304

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GSTK1 and RETREG1/FAM134B-mediated reticulophagy attenuates tubular injury in diabetic nephropathy through endoplasmic reticulum stress and apoptosis.

Zhang S, Chen W, Wang W, Liu Y, Zhao C, Yang K, Dai W, Ou Y, Yin X, Long Y, Liu Y, Zhang L, Sun L, Liu F, Xiao L
Autophagy 2025 Dec;21(12):2826-2841

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Dual mechanisms of Vitisin A in managing alcoholic liver disease: Inhibition of lipogenesis and complement activation.

Zhu Y, Deng H, Liu J, Li X, Huang X, Che Z, Bai W, Jiao R
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Dec;206:115639

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A novel lncRNA, Lnc21q22.11, suppresses gastric cancer growth by inhibiting MEK/ERK pathway.

Zhu C, Zhang M, Yang W, Gao A, Yu X, Su X, Chen R, Guo M
Epigenetics 2025 Dec;20(1):2512764

---

Characterizing stroke-related cellular changes in the surviving neurons of mouse ischemic stroke.

Ikegami T, Sasaki T, Shimbo T, Kitayama T, Yamamoto Y, Ouchi Y, Yamazaki S, Sugiyama S, Nishiyama K, Gon Y, Okazaki S, Todo K, Matsumura S, Tamai K, Mochizuki H
Neurochemistry international 2025 Dec;191:106086

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The phytochemical arbutin exerts potent anti-Toxoplasma effects through activation of cell-autonomous defense mechanisms while attenuating inflammation.

Liu Z, Ma Y, Xiang Y, Shen Y, Liao L, Zhu X, Shi Z, Wei Y, Kou Y, Wang Y
PLoS neglected tropical diseases 2025 Dec;19(12):e0013815

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MiR-646 inhibited cell proliferation and migration by targeting P62 in glioma.

Ye F, Zhang H, Chen Q, Gui Y, Tian G, Ye Y, Chen X, Dong H, Fan X, Chen J, Yuan R, Zhao L, Yu J
Cell adhesion & migration 2025 Dec;19(1):2515763

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Cadinane sesquiterpenes from Alangium platanifolium: structural elucidation and anti-colorectal cancer biological evaluation.

Jiang KY, Zhang H, Du YN, Li ZD, Zhang Z, Deng Q, Wang L, Kong YZ, Wang HN, Sai CM
Fitoterapia 2025 Dec;187:106922

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COL4A2 drives ECM remodeling and stiffness increasing to promote breast cancer metastasis via YAP signaling pathway in dECM induced models.

Peng J, Zhu W, Zhang C, Yin S, Ye J, Mao H, Li M, Zhao J
Biomaterials advances 2025 Dec;177:214430

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Anti-inflammatory Effects of Membrane Vesicles from Eubacterium rectale via the NLRP3 Signal Pathway.

Zhang H, Zhao Y, Li D, Li H, Wang Z, Zhang L, Niu H, Huang Y, Zhao C, Jin Y, Zhou D
Probiotics and antimicrobial proteins 2025 Dec;17(6):4841-4850

---

Defect of MLH1 expression sensitized esophageal squamous cell carcinoma cells to Polθ inhibitor.

Zhou B, Zhang M, Zhu C, Gao A, Su X, Guo M
Epigenomics 2025 Dec;17(18):1347-1354

---

Gut microbiota-regulated unconjugated bilirubin metabolism drives renal calcium oxalate crystal deposition.

Li S, Wu W, Zhou Y, Zhang S, Wei D, Zhu M, Ying X, Sun X, Liu H, Zhu W, Tang D, Jiao R, Zeng G, Duan X, Liu J, Wu W
Gut microbes 2025 Dec;17(1):2546158

---

Lachnospiraceae bacterium alleviates alcohol-associated liver disease by enhancing N-acetyl-glutamic acid levels and inhibiting ferroptosis through the KEAP1-NRF2 pathway.

Zhang H, Hu Q, Zhang Y, Yang L, Tian S, Zhang X, Shen H, Shu H, Xie L, Wu D, Zhou L, Wei X, Cheng C, Jiang J, Wang H, Shen C, Kong D, Xu L
Gut microbes 2025 Dec;17(1):2517821

---

Discovery of novel aniline-pyrimidine analogues as orally bioavailable dual VEGFR-2/tubulin inhibitors with potent antitumor and anti-angiogenesis efficacy.

Chu Y, Huang G, Yao Y, Wang A, Zhang Y, Yang H, Sun M, Duan Y
Bioorganic chemistry 2025 Dec;167:109233

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Design, synthesis, and evaluation of 5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-indole-2-carboxamide derivatives as anti-HCC agents targeting Nur77.

Hu S, Li X, Yu M, Zhang H, Wang X, Qi C, Huang S, Xu Z, Hu H, Chen S, Fang M, Zeng J
Bioorganic chemistry 2025 Dec;167:109113

---

Arginine depletion-induced autophagy and metabolic dysregulation are involved in the disease severity of hand, foot, and mouth disease.

Jin Y, Ji W, Zhang L, Dang D, Yu B, Zhang X, Zhang Y, Li J, Zhang Y, Yang R, Yang H, Chen S, Wang F, Duan G
Virulence 2025 Dec;16(1):2440541

---

Elevated SNHG15 empowers keratinocytes hyperproliferation through activation of STAT3/Cyclin D1 axis in psoriasis.

Tang L, Li G, Chang J, Xian H, Liu Y, Lin L, Dai Z, Liu Z, Qiu X, Zhang B, Su Z, Feng B, Zhu Y, Wang M, Chen Y, Liu H, Wu D, Li C, Zhao J, Li M, Zhu Y, Xie X, Deng H, Ye S, Fan S, Bi H, Lu C, Zheng G
Acta pharmaceutica Sinica. B 2025 Dec;15(12):6430-6443

---

Reactivating T cell immunity in Wnt-hyperactivated non-small cell lung cancer through a supramolecular droplet of carnosic acid and peptide.

Liu N, Tu Y, Wang H, Zheng X, Ji F, Geng M, Wei X, Xin J, He W, Zhao Q, Liu T
Journal of pharmaceutical analysis 2025 Dec;15(12):101309

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Tanshinone IIA attenuates cerebral-ischemia-reperfusion-induced neuroinflammation by inhibiting the TLR4/NF-κB signaling cascade: A study integrating network pharmacology, bioinformatics, and experimental validation.

Zhou C, Yu Z, Chen T, Chen Q, Zhang Y, Cai J, Xu C, Yu L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157548

---

Gut-liver axis mechanisms of Hippophae rhamnoides L. in non-alcoholic fatty liver disease prevention.

Ma J, Li Y, Yang Y, Zhao L, Jiang Y, Wong TW, Zhang D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157517

---

Bu-fei decoction ameliorates naïve CD4(+) T cell senescence and attenuates age-related COPD by regulating the C1qbp-cGAS-STING signaling pathway.

Xu G, Su J, Hong Y, Zhang E, Zheng Z, Li J, Li N, Peng G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157513

---

Diacerein attenuates sepsis shock mortality through combined suppression of vascular inflammation, stiffness, and permeability.

Luo M, Jiang Y, Peng Y, Lv D, He A, Huang L, Xia Y, Luo S, Li Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157510

---

Ginsenoside Rb1 alleviates atherosclerosis by modulating vascular smooth muscle cell proliferation, foam cell formation, and autophagy.

Yuan HH, Yi ZY, Xie LL, Bu LL, Guo MH, Zheng XL
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157503

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Gut microbiota-metabolite crosstalk mediates icariin's protection against obesity-induced spermatogenic dysfunction through NF-κB/AMH axis in Sertoli cells.

Huang Q, Ji L, Meng Z, Huang K, Lei S, Xue H, Zhou Q, Tian Y, Chen T, Lei X, Huang H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157490

---

Electroacupuncture stimulation induced M1/M2 polarization in white adipose tissues by activating the Y1 receptor in obese mice to reduce chronic inflammation.

Lu M, Yu Z, Yang X, Yang Z, Xu T, Yu Z, Jing X, An L, Zhang J, Xu B
Adipocyte 2025 Dec;14(1):2524638

---

Leptin decreases Th17/Treg ratio to facilitate neuroblastoma via inhibiting long-chain fatty acid catabolism in tumor cells.

Li M, Li D, Wang HY, Zhang W, Zhuo Z, Guo H, Liu J, Zhuo Y, Tang J, He J, Miao L
Oncoimmunology 2025 Dec;14(1):2460281

---

ENO1 promotes cancer metastasis via stimulating metabolism reprogramming in osteosarcoma.

Huang P, He S, Qi Z, Nijiati Y, Wang J, Lin Z, Ma Y, Dong R, Chen G, Ning B
British journal of cancer 2025 Dec;133(11):1625-1639

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Erucic Acid, Derived by Lactobacillus Crispatus, Induces Ferroptosis in Cervical Cancer Organoids Through the PPAR-δ Signaling Pathway.

Zhen Q, Xu Y, Xu Y, Liu X, Zhang Y, Ye D, Han S, Liu S, Zhang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(48):e12599

---

Aloe-Emodin Targeting FOXC2 Disrupts NETs Formation and EMT-Driven Postoperative Peritoneal Adhesion Through TGF-β1-Smad2/3 Pathway.

Yang L, Fang Y, Lian Y, Kong Z, Miao J, Chen Y, Li W, Chen F, Zhang B, Chen Y, Bian Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(48):e11013

---

Norepinephrine Induces Sertoli Cell Ferroptosis via Receptors Desensitization Causing Stress-Related Male Reproductive Dysfunction.

Zhang L, Gao S, Xiong X, Liu X, Li R, Wang X, Han L, Xiao X, Wang X, Li W, Chang Y, Du Y, Yang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(48):e04817

---

Hepatitis E Virus ORF1 Polyprotein Harbors a Pocket-Like Cavity That Is Vital for Virus Replication and Represents a Novel Antiviral Target.

Ding X, Zeng D, Liu D, Bian Y, Li B, Li Z, Li Q, Liang S, Si Y, Yao Q, Ding Y, Zhu J, Li X, Zheng K, Guo H, Wang W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(47):e01699

---

Synaptic Dysfunction in the Anterior Cingulate Cortex Underlies Pain-Anxiety Comorbidity in a Mandibular Asymmetry Mouse Model.

Zhang Z, Zhang Y, Si J, Mao H, He F, Ning J, Ma G, Chen X, Xiao H, Zhu Y, Zhang H, Lu Y, Liu Q, Nian M, Sun S, Yu S, Wu S, Fan Z, Jin Z, Huang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e09509

---

NRF2-REGγ-ACADM/KLF15 Signaling Pathway Regulates the Browning of White Adipose Tissue to Modulate Obesity.

Chen H, Guan Q, Gong S, Du Y, Zhang Z, Liu Y, Zhou L, Liu L, Xin B, Guo Y, Zhang H, Zhou Z, Pei T, Yu G, Yin S, Li L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e09429

---

Targeted Degradation of sGRP78 Alleviates the Immunosuppressive Tumor Microenvironment.

Wu Z, Zheng P, Xiao Y, Wang Q, Pan X, Zhou X, Lv Y, Xiao J, He Y, Huang T, Lei P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(45):e09921

---

Procyanidin B3 and Its Derivatives Alleviate Neuronal Injury by Targeting G3BP1 for Ischemic Stroke Therapy.

Zhang H, Zhang Y, Chen Y, Zhong W, Tan S, Wang J, Yan H, Yan N, Lin M, Liu X, Chang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(45):e09781

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RIPK1 Drives JAK1-STAT3 Signaling to Promote CXCL1-Mediated Neutrophil Recruitment in Sepsis-Induced Lung Injury.

Sun H, Li X, Gao S, Jiang Y, Wu X, Chen Z, Wu H, Hua Q, Zu R, Xiang H, Ben-Ami R, Miao C, Tan L, Li Y, Wang J, Chen W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(45):e07123

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Carvacrol alleviates endoplasmic reticulum stress and inflammation induced by lipopolysaccharide by enhancing endoplasmic reticulum autophagy in dairy mammary epithelial cells.

Yang Y, Li M, Wang J, Zhang H, Chang R, Zhao B, Aernouts B, Huang Q, Xu C
Journal of dairy science 2025 Dec;108(12):13919-13937

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Therapeutic Potential of 6-Gingerol in Glioma: Mechanistic Insights and Experimental Validation.

Miao S, Hua W, Wang J, Li L, Sun Y, Shi X, Ma S
Chemical biology & drug design 2025 Dec;106(6):e70217

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Research note: duck Tembusu virus non-structural protein 3 induced autophagy through endoplasmic reticulum stress.

Zhang S, Fu J, Zhu L, Lu Y, Zhang Z, Yu L, Qiu J, Wang G, Li N
Poultry science 2025 Dec;104(12):105990

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The diet-derived gut microbial metabolite 3-phenylpropionic acid reverses insulin resistance and obesity-associated metabolic dysfunction.

Alqudah S, DeLucia B, Osborn LJ, Markley RL, Bobba V, Preston SM, Thambidurai T, Hamidi Nia L, Fulmer CG, Sangwan N, Nemet I, Claesen J
Molecular metabolism 2025 Dec;102:102272

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Furin may contribute to proglucagon processing and glucagon-like Peptide-1 production in human alpha cells.

Koepke J, Long W, Barr A, Light PE
Molecular metabolism 2025 Dec;102:102259

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Ameliorating Acute Kidney Injury Induced by Ischemia-Reperfusion by Targeting Purine Metabolism.

Zhao L, Zhang T, Zhou X
International journal of molecular sciences 2025 Dec 9;26(24)

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Ubiquitin-specific protease 14 inhibition promotes mitophagy and attenuates neural apoptosis after spinal cord injury.

Wu D, Chen D, Chen H, Yu Z, Feng H, Zhou L, Chen Z, Shi T, Wu R, Zhang Y, Sun L, Wang Z, Liu W
Scientific reports 2025 Dec 9;15(1):43741

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Comprehensive analysis of BIRC5: from pan-cancer analysis to experimental validation.

Liao G, Qian J, Wei S, Yan X, Liu Q, Huang Q, Lin Y, Xu G, Zheng B, Chen C, Yang Z
BMC cancer 2025 Dec 8;25(1):1860

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Oolong tea polyphenols alleviate cognitive impairment in sleep-deprived mice through the microbiota-gut-brain axis.

Hu N, Dai H, Tong M, Sun S, Zhao M, Zhang X
Food & function 2025 Dec 8;16(24):9390-9407

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Angiopoietin-like 8 governs osteoblast-adipocyte lineage commitment during skeletal aging.

Guo Y, Zhang Z, He J, Luo P, Wang Z, Zhu Y, Meng X, Pan L, Kan R, Xiang Y, Mao B, He Y, Wang S, Yang Y, Guo F, You H, Li F, Li D, Chen Y, Yu X
JCI insight 2025 Dec 8;10(23)

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Integrated Transcriptomic, Proteomic, and Network Pharmacology Analyses Unravel Key Therapeutic Mechanisms of Xuebijing Injection for Severe Acute Pancreatitis.

Yao L, Yang X, Yuan M, Liu S, Wang Q, Wu Y, Luo W, Wu X, Cai W, Li L, Lin Z, Yang J, Liu T, Sutton R, Szatmary P, Jin T, Xia Q, Huang W
Pharmaceuticals (Basel, Switzerland) 2025 Dec 7;18(12)

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Aberrant adenosine A(2A) receptor signaling in the choroid plexus drives CSF hypersecretion and ventriculomegaly in hydrocephalus.

Zheng W, Hu L, Yang Y, Li X, Wu J, Chen W, Jiang Y, Chen Y, Wang H, Li S, Feng K, Zheng C, Wang Y, Cunha RA, Lv Z, Chen JF
Nature communications 2025 Dec 7;17(1):83

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Lumican from DESC spheroids enhances odontoblastic differentiation of SCAPs.

Zhang Q, Huang S, Liu X, Zhang M, Sun J, Liu M, Nie H, Lei L
Stem cell research & therapy 2025 Dec 7;17(1):27

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Discovery of a selenium-containing compound as a promising ferroptosis inducer attenuates prostate cancer progression.

Xu L, Wang X, Xu Y, Wang Z, Li H, Che Z
European journal of medicinal chemistry 2025 Dec 5;299:118067

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Melatonin Supplementation Relieves Fluoride-Induced Bone Injury via Ion Homeostasis Disorder and PINK1/Parkin-Mediated Mitophagy.

Zhuang C, Zhao J, Zhang X, Guo M, Lu Y, Pei T, Zhao Y, Liang C, Zhang J
Foods (Basel, Switzerland) 2025 Dec 5;14(24)

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High-throughput capture of actively transcribed region-interacting sequences reveals an intricate promoter-centered regulatory network.

Li X, Xu J, Yan X, Zhong J, Hou C, Xiao C, Niu L, Chi W
Molecular cell 2025 Dec 4;85(23):4463-4479.e7

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NEO1 modulates the A1 astrocyte polarization in subarachnoid hemorrhage through the cPLA2-MAVS signaling pathway.

Wu Y, Wei B, Jin L, Li L, Yang Z, Li C, Zhou J, Gong W, Feng X, Guo S, Cheng W, Li R, Liang S, Su S, Jin F, Zhang X, Liu Y, Duan C, Li X, Liu W
Journal of neuroinflammation 2025 Dec 4;23(1):6

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KY216-tubulin complex captures VASH2 to inhibit NSCLC metastasis.

He XY, Liu CY, Ding XY, Lin Q, Leng JF, Xiao CM, Zang X, Wang MY, Yin Y, Kong LY, Xia YZ
Nature communications 2025 Dec 4;17(1):191

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Serum MicroRNA signatures associated with hypertrophic callus formation in polytrauma patients with traumatic brain injury.

Lettner T, Dussing F, Gehwolf R, Deininger C, Deluca A, Wally V, Hofmann V, Hackl M, Traweger A, Wichlas F
Scientific reports 2025 Dec 4;15(1):43154

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Intestinal microbiota contributes to the heterogeneity of fat deposition by promoting mitochondrial fatty acid β-oxidation.

Li L, Zhou N, Wang Z, Wang T, Wang Y, Qiao F, Du ZY, Zhang ML
Gut microbes 2025 Dec 31;17(1):2593076

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CRX is an intrinsic suppressor of epithelial‒mesenchymal transition in retinal pigment epithelial cells: a promising therapeutic avenue for subretinal fibrosis.

Li D, Ou Q, Gao F, Wang X, Zhu L, Zhou Y, Xu JY, Jin C, Wang J, Zhang J, Li J, Bi Y, Lu L, Xu GT, Tian H
Cell death & disease 2025 Dec 31;17(1):156

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Targeting the METTL3/PCNA axis with STM2457 overcomes cisplatin resistance in osteosarcoma.

Yu H, Li S, Liu J
Translational cancer research 2025 Dec 31;14(12):8567-8578

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dentification and characterization of novel PAX4 variants in patients with suspected MODY9.

Chen X, Tian Y, Wu W, Liu L, Wu H, Zhang Y, Suo N, Xu C
BMJ open diabetes research & care 2025 Dec 31;13(6)

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SARS-CoV-2 nsp14 induces the m(7)G methylation and the sequestration of host RNAs in stress granules.

Li X, Huang W, Zhang S, Wang W, Lin J, Wang Z, Zeng Q, Zhang F, Cao M, Chen Y, Peng Z, Sun Q, Liang Z, Zhuang J, Yang H, Hou P, Zhao B, Chen Y, Cao L, Yang Z, Guo D, Pan JA, Peng X
Communications biology 2025 Dec 30;9(1):182

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Targeting IQGAP3 skews macrophages polarization towards M1 phenotype and promotes antitumor immune response.

Li X, An X, Zhang Y, Zhang S, Zeng L, Shi J, Wu S, Wang Y, Xu Y, Lv X, Yang S, Yuan B
Cellular and molecular life sciences : CMLS 2025 Dec 30;83(1):53

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TAGLN: a stiffness-driven prognostic biomarker for metastatic colorectal cancer.

Ye Y, Jia Y, Li W
Cancer cell international 2025 Dec 30;26(1):54

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Integrative multi-omics analysis proposes a metabolic classification of gliomas: distinct metabolic states, immune infiltration, and prognosis.

Zhu Q, Niu W, Mu M, Ye C, Niu C
Journal of translational medicine 2025 Dec 30;24(1):122

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6-gingerol alleviates chemotherapy-induced nausea and vomiting by inhibiting ferroptosis via the regulation of iron homeostasis.

Liang W, Feng L, Han S, Yang C, Ye B, Mo Z, Nie K
Cancer chemotherapy and pharmacology 2025 Dec 3;95(1):119

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Regulation of Melatonin on AQP4 Expression in Brain of SD Newborn Rats with Bilirubin Encephalopathy and Protection Mechanism.

Xue K, Cheng X, Qian W, Mistry H, Fan P, Hu J, Chen C, Zhang L, Vazirinasab P, Huang J, Lu W, Xu J, Zhu S, Qiu G, Ran J, Gan S
Molecular neurobiology 2025 Dec 3;63(1):239

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Deciphering the molecular landscape of NMDAR-E associated ovarian teratomas: a Multi-Omics approach.

Ma L, Sun X, Zhang S, Xiao Y, Guan H, Wang R, Tang Z, Zhang W, Xia H
Journal of ovarian research 2025 Dec 3;18(1):289

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Mitochondrial protease ClpP deficiency protects against tubulointerstitial damage in diabetic kidney disease.

Wang H, Liu Y, Liu J, Zhang S, Li X, Sun L, Liu F, Liu Y, Xiao L
International immunopharmacology 2025 Dec 3;166:115641

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Gpr109a alleviates mammary fibrosis via PPARγ-mediated reduction of ROS and mitochondrial damage.

Bi J, He D, Li F, Xu P, Huang Y, Guo W, Fu S, Kan X, Li Y
International immunopharmacology 2025 Dec 3;166:115603

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Yueju pill and its active component- Myricetin attenuate the reinstatement of methamphetamine-seeking behavior in mice.

Du Y, Fan S, Yang X, Ma W, Li S, Xu Y, Li C, Chen S, Wang Y, Wang M, Ma T, Zhang J
International immunopharmacology 2025 Dec 3;166:115601

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Sofalcone inhibits osteoclastogenesis through Keap1/Nrf2 signaling activation and mitigates ovariectomy-induced bone loss.

Liang H, Wu Q, Hua T, Chen Y, Luo J, Miao J, Su H, Yang S, Xu J, Wang X, Jin H
International immunopharmacology 2025 Dec 3;166:115589

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Six1 promotes alveolar epithelium senescence in pulmonary fibrosis through regulating Tp53.

Fan Y, Tian Z, Zheng H, Xu R, Li B, Wang S, Huang Z, Wang M, Ding D, Zhao J, Xie J
International immunopharmacology 2025 Dec 3;166:115554

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Timosaponin AIII from Anemarrhena asphodeloides binds and inhibits S100A8-mediated neutrophil infiltration and NET formation ameliorates MASH.

Bai Y, Ju J, Xie R, Li J, Zhao X, Fang X, Zhu M, Lan X, Luo H
International immunopharmacology 2025 Dec 3;166:115539

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I-BET151 modulates NLRP3 inflammasome-mediated pyroptosis and exhibits anti-inflammatory activity.

Wu X, Liu W, Meng H, Peng S
Scientific reports 2025 Dec 3;16(1):994

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Adipocytes orchestrate obesity-related chronic inflammation through β2-microglobulin.

Li J, Li Y, Zhou X, Yang S, Liu D, Wen H, Chen X, Duan C, Yu M, Zhang M, Tang B, Wang Y, Wang L, Wu Y
Signal transduction and targeted therapy 2025 Dec 3;10(1):394

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DDRGK1 preserves intervertebral disc development through ufmylation.

Lu M, Zhou T, Yang X, Liu K, Rong K, Ma P, Qin A, Zhao J
Cellular and molecular life sciences : CMLS 2025 Dec 29;83(1):47

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TRIM47-facilitated PLK1 stabilization promotes the proliferation of liver cancer cells.

Xie T, Fan X, Yu T, Zhu Q, Zhang Q, Li N, Wang T, Qian Y, Deng K, Xin H, Li Y, Huang X
Cellular oncology (Dordrecht, Netherlands) 2025 Dec 29;49(1):7

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Dimethyl itaconate suppresses dendritic cell and CD8(+) T cell responses to halt vitiligo.

Wang Y, Chen Y, Ma J, Wu L, Kang P, Chen J, Du P, Wu W, Wang X, He K, Yang Y, Guo S, Guo W, Liu L, Jian Z, Gao T, Li S, Li C
BMC medicine 2025 Dec 29;23(1):698

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Aurora B maintains spherical shape of mitotic cells via simultaneously stabilizing myosin II and vimentin.

Hou C, Yu F, Cao C, Wang T, Pan Z, Zhong M, Liu X, Yao X, Zhang K, Yang Z, Guo J
Journal of molecular cell biology 2025 Dec 29;17(5)

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Pilose antler extract promotes angiogenesis and vascular maturation to accelerate wound healing.

Li L, Wang Y, Ma Y, Gong J, Ren X, Sun Y
Scientific reports 2025 Dec 29;16(1):3643

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LncRNA AC040169.1 is regulated by m6A modification and suppresses ferroptosis via SLC7A11 to promote ovarian cancer progression.

Yang H, Dong Y, Li R, Zhu L, Yang L
Journal of ovarian research 2025 Dec 28;19(1):32

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Cytochrome c Oxidase Subunit COX4-1 Reprograms Erastin-Induced Cell Death from Ferroptosis to Apoptosis: A Transmitochondrial Study.

Oliva CR, Flor S, Griguer CE
Antioxidants (Basel, Switzerland) 2025 Dec 28;15(1)

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Tumor-secreted factors induce aberrant accumulation of vitamin A-enriched lipid droplets in the liver.

Huang X, Zhou W, Hou W, Zhou Y, Li M, Zhang Y, Zhang Q, Yan W, Zhang D, Lee HJ
Communications biology 2025 Dec 27;9(1):125

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Intravenous delivery of mesenchymal stromal cells reverses Müller cell endoplasmic reticulum stress in diabetic retinopathy.

Yan W, Guo R, Liu T, Liu Y, Ping R, Liu B, He J, Griffin MD, Hynes SO, Shen S, Liu Y, Ma J, O'Brien T
Stem cell research & therapy 2025 Dec 27;17(1):55

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High-fat diet disrupts a septal control on feeding to promote obesity in male mice.

Jiang S, Lai S, Jing H, Wu X, Li F, Chen B, Bao J, Wang L, Chen G, Zhu Y
Nature communications 2025 Dec 27;17(1):1248

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Functional extracellular vesicles enable injectable hydrogels with stable osteogenic properties for minimally invasive bone defect repair.

Liu G, Xie Z, Fu X, Wu M
Scientific reports 2025 Dec 27;16(1):2350

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PRAS40 promotes colorectal cancer stemness by enhancing glycolysis through triggering PGK1 acetylation.

Zhang C, Bo Y, Zhang T, Chen X, Zhang T, Teng H, Wang Y, Luo Y, Sun J, Wang L, Wang X, Huang L
Oncogenesis 2025 Dec 27;15(1):2

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Acupuncture Modulates NMDAR-PP1/Calpain1-KCC2 Pathway to Ameliorate Spinal Hyperexcitability and Spastic Hemiplegia Induced by Ischemic Stroke.

He JL, Ma LX, Zhuang YX, Wen JS, Ma LH, Xiu JY, Chen MY
Journal of integrative neuroscience 2025 Dec 26;24(12):46980

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Design and Optimization of LOXL2 and sGC Dual-Target Regulators Targeting Extracellular Matrix Dysregulation and Vasodilation for the Treatment of Pulmonary Arterial Hypertension.

Hu Y, Wang Y, Tan W, Zhao C, Li M, Xiang S, Liang X, Gao R, Zeng B, Chen Z, Hu L, Li Q
Journal of medicinal chemistry 2025 Dec 25;68(24):26547-26573

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Discovery of Imidazo[1,2-b]pyridazine Derivatives as Potent PI3K/mTOR Dual Inhibitors for the Treatment of Pulmonary Fibrosis.

Zeng W, Hua X, Wang Z, Li K, Yin Y, Li XW, Dong S, Ma M
Journal of medicinal chemistry 2025 Dec 25;68(24):26418-26431

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An Enhanced Cancer Immunogenic Cell Death Strategy: Fibrate-Oxaliplatin(IV) Conjugates with Modulating Tumor Immune Microenvironment.

Liang XJ, Guo X, Zhu PH, Zhao ZH, You Z, Yang K, Song Y, Li L, Song XQ
Journal of medicinal chemistry 2025 Dec 25;68(24):26328-26347

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Photobiomodulation mitigates chondrocyte catabolism in osteoarthritis by modulating macrophage M1 polarization through the IL-6/JAK/STAT pathway.

Wang H, Ning W, Liu Y, Nie J, Du S, Zhang H
Journal of orthopaedic surgery and research 2025 Dec 24;20(1):1082

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Novel biallelic MEI1 variants cause female infertility characterized by multiple pronuclei formation and aberrant embryonic development.

Jiao X, Zhu Y, Liu W, Liang Y, Zuo X, Zhou L, Xia Y, Zhang Q, Chen H, Yuan P
Journal of ovarian research 2025 Dec 24;18(1):300

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ALDH3A2 negatively orchestrates gastric cancer progression through a synergistic induction of ferroptosis and ferroptosis-driven macrophage reprogramming.

Ren Y, Cui Y, Wang Z, Luo Y, Jin J, Yuan Y, Li X, Zhang Y, Cao N, Li X, Yu Y, Xiong Y
Cell death & disease 2025 Dec 24;17(1):97

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SERPINB3 enhances NPM1 sumoylation via inhibiting SENP3's activity and promotes lung tumorigenesis.

Meng X, Wang W, Sheshadri N, Zhang T, Han X, Sun Y, Xiao M, Feng Y, Gao S, Chen J, Xie S, Wang Y, Yang Y, Zhao Y, Yin Y, Zong WX, Gao S
Cell death & disease 2025 Dec 24;17(1):133

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Targeting MED23 inhibits hepatocellular carcinoma development by suppressing compensatory proliferation and facilitating ROS-mediated cell death.

Zhao X, Wang Z, Min L, Cao D, Chu Y, Li C, Cai J, Wang G
Cell death & disease 2025 Dec 24;17(1):131

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Pre-activation timing determines influenza severity and viral pathogenicity via STING Inhibition.

Zhu T, Zhu M, Lu F, Qu K, Wang H, Wang S, Sun Z, Yu Y, Wang L, Yan C
Scientific reports 2025 Dec 24;15(1):44501

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SLC44A1 deficiency impedes myelin development in the central nervous system.

Chen Q, Chen X, Li Z, Shao Q, Huang H, Zhou W, Qiu M, Su Z, Liu P, He C
Cell reports 2025 Dec 23;44(12):116617

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Senescence-Primed Ferroptosis Enabled by a Metal-Organic Framework Nanoplatform for Enhanced Cancer Therapy.

Yang Z, Peng Y, Zang J, Wang J, Wang Z, Zhang G, Sun J, Chen H, Xie Y, Peng X, Shan X, Wang Y, Zhang L, Li Y
ACS nano 2025 Dec 23;19(50):42689-42704

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Enhanced therapeutic efficacy of repeated bone marrow-derived MSC administration in a murine model of pulmonary fibrosis.

Zhou Z, Ding J, Han S, Duan Y, Chao J, Huang J
Stem cell research & therapy 2025 Dec 23;17(1):48

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TRIM16 mediates YAP1 K63-linked ubiquitination to alleviate sepsis-induced acute liver injury through YAP/Nrf2 axis in mice.

Zhang K, Liu M, Zheng Y, Gao Z, Dong Z, You M, Guo Y, Liang F, Zhao Z
Cell & bioscience 2025 Dec 23;16(1):7

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NEDD4 suppresses ferroptosis in lung ischemia-reperfusion injury by ubiquitinating and degrading SLC1A5.

Li J, Meng F, Qian X, Chen S
Scientific reports 2025 Dec 23;16(1):2568

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The Indicine X-linked CYBBL237M Mutation Can Suppress Intracellular Infection with Tubercle Bacilli.

Wang H, Xia X, Zeng L, Yang J, Han J, MacHugh DE, Lenstra JA, Song Y, Fan A, Zhu Y, Zhu Z, Zhang X, Chen Y, Han J, Lei C, Chen N, Zhang Y, Gao Y
Genomics, proteomics & bioinformatics 2025 Dec 23;

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Propofol addiction drives neuronal senescence and cognitive decline via autophagy-mediated ADAR1/SIRT1 disruption.

Wang X, Lin S, Zou Z, Zhu D, Zhou J, Zhang X, Lv J, Zhou W, Liu Y, Si Z
Communications biology 2025 Dec 22;8(1):1832

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DNAJA2 inhibits Newcastle disease virus replication by targeting its V protein to modulate the MDA5-MAVS pathway.

Mo J, Zhang F, Jiang Y, Li M, Wu S, Chen R
BMC microbiology 2025 Dec 22;26(1):84

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Activation of the cGAS-STING pathway by clofoctol through mitochondrial damage in triple-negative breast cancer.

Wang L, Zheng L, Yong X, Ding Z, Sun J, Tang Y, Tang K, Li Y, Chen J, Qi S, Hu H, Tang H
Journal of translational medicine 2025 Dec 22;24(1):70

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Necroptotic signaling orchestrates glioblastoma malignancy and potentiates temozolomide response.

Li Y, Qiu Y, Gao W, Geng L, Wu Z, Zhang T, Pan J, Lu J, Zhang D, Idris A, Hou L, Su Z, Li J
Cell death & disease 2025 Dec 22;16(1):921

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A protein complex in the extreme distal tip of vertebrate motile cilia controls their organization, length, and function.

Hong J, Lee C, Madhu G, Papoulas O, Atayeter E, Hoogerbrugge G, Pan J, Takagishi M, Manzi NI, Dickinson DJ, Horani A, Brody SL, Marcotte EM, Prakash VN, Park TJ, Wallingford JB
Nature communications 2025 Dec 21;17(1):394

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The GATA3-STEAP4 Axis Drives Inflammation by Promoting Th2 Differentiation in Allergic Rhinitis.

Ding X, Su H, Liu T, Chen Y, Gao Z, Chang Z, Bai W
Inflammation 2025 Dec 20;49(1):13

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Alpha-1 Antitrypsin Mediates Spontaneous Resolution of Acute Gouty Inflammation Via Inhibiting Caspase 3/GSDME-dependent Macrophage Pyroptosis.

Li X, Liu L, Tong S, Wang F, Zhu L, Cheng Q, Zhang P, Chen M, Xie Y, Wang L, Yu H, Wu H
Inflammation 2025 Dec 20;49(1):12

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Cholesterol induced-mitochondrial calcium dysregulation facilitates atherosclerosis by promoting lipid accumulation in vascular smooth muscle cells.

Zhang Z, Yang F, Wang W, Cao Q, Zhang L, Zhang Y, Ma D, Zhang X, Wen J, Zheng B
Molecular biomedicine 2025 Dec 2;6(1):129

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Extracellular vesicles from obese visceral adipose promote pancreatic cancer development and resistance to immune checkpoint blockade therapy.

Xue C, Zhao S, Zhou Y, Chen Z, Liu J, Deng S, Zeng L, Zhao H, Xu Z, Li M, He X, Liu S, Liu S, Zhang S, Peng X, Wu X, Bai R, Zhuang L, Wu S, Zhang J, Lin D, Huang X, Zheng J
Cell metabolism 2025 Dec 2;37(12):2381-2401.e9

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Promoting astrocyte-neuron triiodothyronine shuttling attenuates brain damage in neonatal hypoxic-ischemic encephalopathy.

Yu G, Yang Y, Zhou W, Wang X, Feng Y, Wang X, Lin Z
Journal of neuroinflammation 2025 Dec 2;23(1):5

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DHX36 plays an oncogenic role in breast cancer progression and invasiveness.

Wei C, Xu D, Cheng J, Zheng M, Li T, Yang J, He J, El-Far AH, Zhang L, Xiao X, He T, Fu J
Scientific reports 2025 Dec 2;16(1):1156

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Sustained reductions in valine and isoleucine mediate anti-cancer pharmacological effects of inhibiting amino acid transporter LAT1 in cancer cells.

Nishikubo K, Ohgaki R, Okanishi H, Xu M, Kanai Y
Cancer & metabolism 2025 Dec 2;13(1):46

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Hypoxia-induced USP13 expression drives ferroptosis resistance and tumor immune evasion in hepatocellular carcinoma through the stabilization of ACLY.

Hu K, Li J, Chen K, Mi X, Pan Y, Tang J, Cao J, Zhong X
Cell death discovery 2025 Dec 2;12(1):28

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Proteomics- and BRET- screens identify SPRY2 as a Ras effector that impacts its membrane organization.

Pavic K, Hood FE, Duval CJ, Manoharan GB, Laurini C, Siddiqui FA, Mo SPL, Prior IA, Abankwa DK
iScience 2025 Dec 19;28(12):113974

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Microglial Prrc2a regulates microglia-neuron interaction in cerebellum and motor functions in mice.

Li X, Yang P, Dong B, Jiang L, Xiu R, Guo J, Li S, Zhang P, Gu R, Li A, Zhang J, Wu R, Wang F, Shen Y, Shao N, Cheng J, Yuan Z
iScience 2025 Dec 19;28(12):113949

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PSMD8 cooperates with USP14 to promote bladder cancer progression by inhibiting ferroptosis.

Wang X, Liu B, Tang Y, Wang J, Ren J, Hu R, Chen W, Fu D, Wu Y, Gui T, Wang J, Han P, Wei X, Li H, Bai Y
iScience 2025 Dec 19;28(12):113938

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Depletion of LINC01133 from cancer-associated fibroblasts exacerbates the progression of gastric adenocarcinoma.

Liang X, Jiang S, Zhang Q, Li J, Dong K, Zhang H, Wang L, Guan X, Wang Y, Fang T, Xue Y, Li Y, Qin W, Yu J, Wu J, Meng X, Sun W, Weng Y, Li M, Fu G, Pang S, Li L, Fu S, Cai M
iScience 2025 Dec 19;28(12):113886

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Discovery and validation of RAB3B as a diagnostic biomarker for prostate cancer with serum PSA below 10 ng/mL based on a multi-omics study.

Zhao C, Deng G, Chen J, Li H, Fan R, Fu Z, Ye D, Lai C, Di J
Cancer cell international 2025 Dec 19;26(1):34

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Structural insights into cationic amino acid transport and viral receptor engagement by CAT1.

Xia L, Lin B, Zou R, Wu Y, Xu J, Pan Y, Yuan Y, Li S, Yang Y, Chen X
Nature communications 2025 Dec 18;17(1):1108

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Mechanistic Study of Hypoxia-Mediated Regulation of Osteoblast Senescence via ATP6V1A-Dependent Modulation of Metabolic Remodeling.

Xiao H, Chen Y, Liu X, Chen R, Yang C, Yang F, Chen C, Geng B, Xia Y
Biology 2025 Dec 18;14(12)

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Investigation of a Neuroprotective Peptide from Round Scad (Decapterus maruadsi): Bioactivity Validation, Gastrointestinal Digestion Stability, and Structure-Activity Relationship Analysis.

Zhang Q, Zhao L, Li C, Chang X, Zhu L, Zhang Y, Ding W
Journal of agricultural and food chemistry 2025 Dec 17;73(50):32302-32314

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TREML2 Modulates Microglial Phagocytosis of Myelin Debris via TLR9 in Chronic Cerebral Ischemia.

Xu ZH, Qi JW, He XY, Wang SY, Chen SY, Gu YC, Xie Y, Zhang YD, Jiang T
Inflammation 2025 Dec 17;49(1):4

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Alkaline Phosphatase-Triggered Spatiotemporal Repair of Corneal Injury with TB500 Peptide Hydrogel.

Lu P, Shan M, Peng C, Ji W, Yang T, Yang Z, Zhang Z, Wang Y
ACS applied materials & interfaces 2025 Dec 17;17(50):67503-67518

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Quercetin Regulates Autophagy to Inhibit PRRSV Replication Through the PI3K/Akt/mTOR Signaling Pathway.

Yang Y, Li X, Shi H, Yu J, Gao C, Liu Y, Feng W, Peng L, Fu B, Yi P
Viruses 2025 Dec 17;17(12)

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Global remodeling of ADP-ribosylation by PARP1 suppresses influenza A virus infection.

Zhang Z, Uribe I, Davis KA, McPherson RL, Larson GP, Badiee M, Tran V, Ledwith MP, Feltman EM, Yú S, Caì Y, Chang CY, Yang X, Ma Z, Chang P, Kuhn JH, Leung AKL, Mehle A
Nature communications 2025 Dec 17;16(1):11176

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Tie1 derived from cervical cancer promotes the invasion and metastasis by Ang1 mediating Tie2/PI3K/Akt signaling axis and angiogenesis.

Wei H, Wang X, Wang Q, Lin B, Liu X, Shi Y
Scientific reports 2025 Dec 17;15(1):43979

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Integrated multi-omics analysis revealed that SMARCAL1 serves as an immune related prognostic marker and promotes liver cancer growth via the Hippo/YAP signaling axis.

Huang T, Tang M, Tang Q, Di Y, Wang J, Duan Y, Zhang C, Bi F
International journal of surgery (London, England) 2025 Dec 17;112(4):10192-205

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BAG3 modulates clathrin-mediated endocytosis and tau uptake in astrocytes.

Rodwell-Bullock J, Blau E, Ganguly A, Deaton C, Johnson GVW
bioRxiv : the preprint server for biology 2025 Dec 17;

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STAT2 Promotes Tumor Growth in Colorectal Cancer Independent of Type I IFN Receptor Signaling.

Canar J, Bono M, Alvarado A, Slifker M, Sitia G, Gamero AM
Current oncology (Toronto, Ont.) 2025 Dec 16;32(12)

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TXNIP regulates the proliferation of scar fibroblasts through oxidative stress.

Gong W, Zhang S, Zhang R, Li Y, Zhai X
European journal of medical research 2025 Dec 16;30(1):1240

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ENO1 blockade augment ferroptosis susceptibility in TKIs-resistant CML through GPX4 autophagic degradation.

Hongwei P, Xintong Y, Zhiwei C, Jinfang H, Dongsheng X, Jiaqi W, Zhen L, Yue L, Xu W, Simei R, Fei L
Free radical biology & medicine 2025 Dec 16;241:899-913

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Transcription factor EGR2 drives cataract formation through IGFBP3-mediated oxidative injury in lens epithelial cells.

Li W, Zou Y, Zheng W, Zhang J, Cen C, Li R, Cheng H, Hou S, Wan W, Liang L, Kang J, Zheng S, Hu K
Free radical biology & medicine 2025 Dec 16;241:773-788

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Aldehyde dehydrogenase ALDH3A1 rescues cigarette smoke-induced emphysema by conferring alveolar type 2 to type 1 cell transition.

Cui J, Han S, Li J, Li X, Liang L
Free radical biology & medicine 2025 Dec 16;241:511-525

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LLDT-8 attenuates brain metastasis in non-small cell lung cancer via selective p53 activation.

Liu J, Liang L, Wang Z, Wei K, Liang Z, Chang J, Lan R, Wang C, Yu M
RSC medicinal chemistry 2025 Dec 16;17(1):686-97

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Decreased scleral Wnt5a(hi) fibroblasts exacerbate myopia progression by disrupting extracellular matrix homeostasis in mice.

Zhu H, Chen W, Ling X, Jiao S, Yu L, Liu H, Ding M, Zhang F, Zhou Y, Pan Y, Zhou Z, Qu J, Zhao F, Zhao F, Zhou X
Nature communications 2025 Dec 16;17(1):554

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Interleukin-38 Ameliorates Atherosclerosis by Inhibiting Macrophage M1-like Polarization and Apoptosis.

Li Z, Li X, Shen R, Wang Y, Yu J, Pan C, Cai Y, Dong Q, Yu K, Zeng Q
Biomolecules 2025 Dec 16;15(12)

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d-serine prevents cognitive impairment in a mouse model of NMDAR encephalitis.

Luo H, Han Z, Yang J, Yang X, Li Y, Huang D, Ding R, Cheng L, Ma J, Jiang L
Journal of neuroimmunology 2025 Dec 15;409:578768

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CRTC2 Promotes AML Progression and Mediates Mitochondrially-Driven Venetoclax Resistance.

Liang X, Zheng Y, Jiang B, Huang Y, Tang J, Deng H, Zhang C, Zhao M, Lin D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Dec 15;39(23):e71316

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The Role of STING-Mediated Activation of the Integrated Stress Response in Inflammation-Induced Depletion of Ovarian Reserve.

Wang Q, Wu Y, Dong X, Wu Y, Dai Y, Cao Y, Du Y, Lv H, Wei K, Cao L, Yan L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Dec 15;39(23):e71286

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Biphasic Regulation of TLR7/MyD88/IRF7-IFN-β Axis by Toxoplasma gondii Facilitates Immune Evasion.

Liu X, Wang Y, Wu K, Xie J, Liu K, Xiao Y, Ma L, Ngim C, Hu D, Lang J, Wang Z, Zhang Z, Jiang L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Dec 15;39(23):e71278

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Pathogenic Mechanism of the KCNQ4 Gene Variant in Hearing Loss and Functional Validation in a Zebrafish Model.

Jia H, Liu X, Chen H, Wang Y, Guan MX, Guo Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Dec 15;39(23):e71274

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Early life exposure to environmental levels of PCB138 induces lipid metabolism disorders through activating aryl hydrocarbon receptor in female mice.

Zhu S, He R, Ruan J, Chen P, Zhang Y, Yang C, Wang W, He C, Zuo Z
Environmental research 2025 Dec 15;287:123038

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Integrative analysis of gut microbiome and serum metabolomics explores the therapeutic mechanism of tongfeng qingxiao prescription in treating gouty arthritis.

Huang X, Hu L, Sun W, Shao Z, Ma W, Yuan Q, Liu J, Wu D, Cheng L, Li H
Journal of pharmaceutical and biomedical analysis 2025 Dec 15;266:117121

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Antigen B from Echinococcus granulosus regulates autophagy-mediated macrophage polarization to alleviate immune thrombocytopenia.

Song HC, Li DL, Wang JJ, Jiao HJ, Li MW, Zhao L, Yang XH, Yan M
Parasites & vectors 2025 Dec 15;19(1):38

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Slc22a17 governs postnatal neurogenesis by maintaining the iron homeostasis in hippocampus.

Tao L, Teng L, Ge M, Wang Y, Hu C, Chen J, Zhao J, Cheng L, Zhang Z, Qin W, Jia Y, Mi D, Yuan Z, Chen L
Nature communications 2025 Dec 15;16(1):11117

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Stimulated thyroid hormone synthesis machinery drives thyrocyte cell death independent of ER stress.

Young C, Zhang X, Wang X, Kellogg AP, Pena K, Cumming AZ, Liao XH, Larkin D, Zhang H, Mastroianni E, Grasberger H, Refetoff S, Arvan P
The Journal of clinical investigation 2025 Dec 15;135(24)

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Leukemia-expanded splenic CD81+ erythroblasts potentiate disease progression in mice by reshaping leukemic cell metabolism.

Li Y, Cao J, Tong J, Tang P, Chen H, Sun G, Yang Z, Zhang X, Dong F, Yang S, Gao J, Zhao X, Ma J, Wang D, Zhang L, Wang L, Cheng T, Cheng H, Shi L
The Journal of clinical investigation 2025 Dec 15;135(24)

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TRIM14 Regulation of Copper Homeostasis and Cuproptosis: A New Strategy to Overcome Chemoresistance in Glioblastoma.

Wang J, Zhang E, Chen S, Wang H, Huang Y, Lan W
Biomedicines 2025 Dec 15;13(12)

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CUL4B promotes hepatocellular carcinoma progression and oxaliplatin resistance by facilitating FUS degradation.

Wei JD, Cheng K, Wu X, Zhang L, Wang Q, Liang Y, Zhu Z, Meng W, Chen W, Guan X, Yang H, Zhou L
Cell death & disease 2025 Dec 14;17(1):116

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FUT3 mediated GRP78 fucosylation promotes colorectal cancer survival and proliferation under glucose restriction via PERK/ATF4/STC2 axis.

Qin K, Zhang H, Shi Y, Wu R, Wu C, Wu Y, He C, Han Z, Luo Y, Fang Y, Yan X, Wang X, Li M, Li A, Liu S, Li Q
NPJ precision oncology 2025 Dec 14;10(1):19

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Multi-cohort analysis and experimental study on the function of squalene epoxidase as a ferroptosis inhibitor in HCC.

Yang X, Wu Y, Zhang Q, Zhou Y, Chang S, Zhang C, Liu D
BMC cancer 2025 Dec 13;26(1):81

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Collateral metabolic vulnerabilities unveiled by loss of isozyme diversity in breast cancer.

Ding R, Yu TJ, Jiang YZ, Xiao Y, Shao ZM
Genome medicine 2025 Dec 12;18(1):7

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LRRC59 cooperates with nuclear transporters to restrain the nuclear envelope repair machinery and safeguard genome integrity.

Timmer R, Bellanger A, Peeters S, Kim H, de la Ballina LR, Eikvar S, Arns AJ, Oortgijs E, Sekulić N, De Vos WH, Campsteijn C
Nature communications 2025 Dec 12;16(1):11211

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Machine learning-based identification of kbhb-affected tumor cell subsets as prognostic and therapeutic targets in breast cancer.

Yuan Q, Sha Y, Ye R, Yu H, Ni L, Han J, Deng L
Journal of translational medicine 2025 Dec 11;24(1):71

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Repetitive unidirectional spinal tactile stimulation engages microglial Bmal1 pathways to promote synaptic remodeling in the mPFC of adolescent VPA-exposed mice.

Chen YN, Zhao ST, Hu MA, Li W, Yu J, Ma MJ, Tang LY, Feng X, Li JS, Zhang YX
Journal of neuroinflammation 2025 Dec 11;23(1):23

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Innate immune and metabolic signals induce mitochondria-dependent membrane lysis via mitoxyperiosis.

Wang Y, Lu J, Carisey AF, Chadchan SB, Lee HW, Malireddi RKS, Sharma BR, Pandian N, Tweedell RE, Palacios G, Becerra Mora N, Robinson CG, Pitre A, Vogel P, Chen T, Murphy MP, Kanneganti TD
Cell 2025 Dec 11;188(25):7155-7174.e25

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Co-condensation between transcription factor and cBAF selectively modulates chromatin remodeling and gene expression.

Ye X, Xu L, Sun X, Gai Y, Yang H, Sun Q, Song J, Huang P, Zhou Q, Li Y, Li N, Jin J, Li Y, Rao W, Lu H, Wang P, Chang C, Lu Y
Nature communications 2025 Dec 11;17(1):673

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Targeted NanoBiT Screening Identifies a Novel Interaction Between SNAPIN and Influenza A Virus M1 Protein.

Zhang X, Wang H, Zhao C, Shi W, Wen F, Qiang H, Liu S, Li P, Chen X, Zhang C, Huang J, Wang Y, Zhang Z, Ma S
Biology 2025 Dec 11;14(12)

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Therapeutic targeting SPI1 in combination with erastin promotes ferroptosis in ccRCC.

Xue W, Wu Z, Li J, Jin P, Zhu Y, Li Z, Wang Z, Li Z, Fei X
Communications biology 2025 Dec 10;8(1):1772

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Exosomal miR-223-3p from mesenchymal stem cells targets FBXW7 to inhibit intervertebral disc degeneration: mechanism insights.

Chen R, Cao K, Gong Y, Zhu Y, Pan W, Zhou Q
Journal of orthopaedic surgery and research 2025 Dec 10;21(1)

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A study on the mechanism by which BCAT1 influences the formation of intracranial aneurysms by regulating autophagy through endoplasmic reticulum stress.

Liu S, Guan H, Wang F
International immunopharmacology 2025 Dec 10;167:115667

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NDUFAB1 promotes hepatocellular carcinoma progression by disrupting mitochondrial homeostasis and mitophagy pathway.

Yao Z, Tan X, Cui H, Liang H, Zhong A, Man Y, Yi T, Zhang Z, Guo X, Tan S, Zhu X
International immunopharmacology 2025 Dec 10;167:115664

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Pneumococcal H₂O₂ reshapes mitochondrial function and reprograms host cell metabolism.

Scasny A, Alibayov B, Hoang N, Jop Vidal AG, Takeshita K, Bautista-Muñoz C, Bengten E, Baez A, Li W, Hosler J, Warncke K, Edwards KS, Vidal JE
mBio 2025 Dec 10;16(12):e0201925

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De-ubiquitinase USP35 promotes peritoneal dissemination of gastric cancer by regulating metabolic reprogramming.

Yan L, Chen M, Cai L, Liu A, Li F, Zhang Y, Peng X, Wang Y, Li R, Mei J, Zou D, Gao X, Wang Y, Wu L, Zhang Y
Cell death & disease 2025 Dec 10;16(1):889

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Resolvin D1 Modulates the Inflammatory Processes of Human Periodontal Ligament Cells via NF-κB and MAPK Signaling Pathways.

Yan J, Cai J, Pan X, Li S, Fenton CG, Fenton KA, Kantarci A, Xue Y, Xue Y, Xing Z
Biomedicines 2025 Dec 10;13(12)

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Glutaredoxin 2 Protects Lens Epithelial Cells From Ferroptosis by Preventing HNRNPA2B1 S-Glutathionylation in Diabetes-Mediated Cataractogenesis.

Li X, Guo Z, Li C, Zhang S, Liang C, Chen X, Guo C, Yan H
Investigative ophthalmology & visual science 2025 Dec 1;66(15):58

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Auranofin facilitates gemcitabine sensitivity by regulating TXNRD1-related ferroptosis in pancreatic ductal adenocarcinoma.

Lu SY, Fang DL, Zhao ZY, Zhu YQ, Liu ZD, Ma MJ, Ye JY, Xu QC, Yin XY
Cancer letters 2025 Dec 1;634:218058

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Nrf2/Bach1 axis regulates redox homeostasis and energy metabolism to optimize Sertoli cell-mediated efferocytosis.

Wu D, Zhang K, Tan J, Khan FA, Huang C, Sun F
Molecular and cellular endocrinology 2025 Dec 1;610:112661

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Kirenol attenuates pressure overload-induced heart failure by enhancing autophagy in macrophages.

Huang Z, Pan L, Xiao Z, Rao F, Yakupu W, Rouzi A, Cheng K, Pang Y, Su Y, Wu D
International journal of cardiology 2025 Dec 1;440:133681

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Esaxerenone inhibits renal macrophage proliferation through MR/TGF-β1 pathway in db/db mice.

Yang F, Liu Z, Li Y, Lv R, Zhao Y, Yang F, Shimosawa T, Tan J, Xu Q, Qiang P
Life sciences 2025 Dec 1;382:124008

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Microglial-derived nitric oxide regulates amygdala synaptic plasticity to drive chronic pain and depression induced by lumbar disc herniation.

Huang Z, Sun J, Li H, Hu Z, Tan H, Fu Y, Gao L, Peng X, Lou H
Neuropharmacology 2025 Dec 1;280:110662

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The metabolic crossroads: glycolysis in cancer and neurodegeneration.

Zeng S, Liu H, Han S, Chen J, Yang Y, Zhang J
BMC neurology 2025 Dec 1;26(1):9

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Epimedokoreanin B blocks autophagic flux to inhibit progression of triple negative breast cancer through targeting MCOLN1/TRPML1 channel.

Zhao C, Zhang P, Yang X, Liu M, Guan Z, Ma B, Duan X, Su C
Free radical biology & medicine 2025 Dec 1;240:222-237

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The DRP1 inhibitory peptide P110 provides neuroprotection after subarachnoid hemorrhage by suppressing neuronal apoptosis and stabilizing the blood-brain barrier.

Hao S, Luo J, Yuan S, Chen W, Zhang X, Zhao C, Xu H, Liu Z, Zhang D
Free radical biology & medicine 2025 Dec 1;240:1-14

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Bile canaliculi formation in primary hepatocytes requires α1β1 integrin-dependent adherens junction re-organization.

Cohen D, Lázaro-Diéguez F, Müsch A
Journal of cell science 2025 Dec 1;138(23)

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Curcumin derivatives as ferroptosis inducers: design, synthesis and anti breast cancer activity evaluation.

Wu N, Zhang Y, Yin X, Du P, Piao Y, Zhao J, Zhu J, Quan Z, Wu CZ, Jin L, Zhang C
Bioorganic & medicinal chemistry 2025 Dec 1;130:118374

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A critical role of the Erk1/2 downstream targets c-Fos, Egr-1, and Egr-2 in PU.1-driven monocyte development.

Bashir HS, G C B, Rahman AA, Dong F
Journal of leukocyte biology 2025 Dec 1;117(12)

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Inhibition of Mettl3-mediated m6A RNA modification of HMGCS1 protects retinal ganglion cells from glutamate excitotoxicity-induced ferroptosis in a rat model of glaucoma.

Wang C, Feng L, Fang W, Zhang C, Zhang W, Zhu W, He Y, Xia Z, Song W, Xia X
International journal of surgery (London, England) 2025 Dec 1;111(12):9147-9165

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Optimal injection sites for therapeutic angiogenesis: HGF-mediated regulation of HIF-1α via MAPK/PI3K pathways in hypoxic endothelial cells.

Wang P, Rong Z, Li F, Ma S, Qiu H, Lian W, Li Z, Chen T, Zhong Q, Wang W, Sun G, Liu C, Ni L, Di X
Tissue & cell 2025 Aug;95:102871

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A high-fat diet suppresses growth hormone synthesis and secretion by influencing the Vit D receptor and Pit1.

Yu H, Guo B, Miao Z, Chen C, Song Y, Yang J
Endocrine 2025 Aug;89(2):508-520

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ANP32E expression in pancreatic cancer is associated with impaired gemcitabine efficacy and poor patient prognosis.

Liu X, Zhao Y, Zhang L, Wang J, Luo L, Zhang S, Zhu Q, Shi Y, Yuan C, Xiao Q, Xiong M, Duan Y, Chen H, Yao H, Cai L, Zhang J, Li G, Li L
Molecular and cellular probes 2025 Aug;82:102030

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Integrated stress response activation induced by usnic acid alleviates BCL-2 inhibitor ABT-199 resistance in acute myeloid leukemia.

Wu D, Li M, Hong Y, Jin L, Liu Q, Sun C, Li L, Han X, Deng S, Feng Y, Shen Y, Kai G
Journal of advanced research 2025 Aug;74:621-635

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GPR30 Inhibits Neuronal Apoptosis After Subarachnoid Hemorrhage by Activating the Wnt/β-Catenin Pathway in a m6A-dependent Manner.

Peng J, He J, Hu X, Xia Y
Molecular neurobiology 2025 Aug;62(8):9638-9650

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Scutellarin Modulates Astrocyte-Microglia-Neuron Crosstalk to Mitigate Neuroinflammation and Apoptosis in Cerebral Ischemia.

Chen H, Duan Z, Jia Q, Zhang X, Xu D, Zheng L, Qi Z, Yang Y, Yang L, Wu C
Molecular neurobiology 2025 Aug;62(8):10834-10855

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Lactiplantibacillus plantarum promotes lactoferrin synthesis and secretion in bovine mammary epithelial cells through STAT3 and AP-1 transcription factor pathways.

Zhou J, Lian S, Geng Z, Yang Y, Wu R, Wang J
In vitro cellular & developmental biology. Animal 2025 Aug;61(7):886-897

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5-Methoxytryptophan improves cerebrovascular injury induced by chronic kidney disease through NF-κB pathway.

Zhou X, Sun Y, Yang G
In vitro cellular & developmental biology. Animal 2025 Aug;61(7):774-788

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Impact of intercellular adhesion molecule 1-positive dental pulp stem cells in deep caries progression.

Zhang Y, Zhang Y, Chen Y, Wu W, Sun J, Zhang X, Zhang J, Chen Z
International endodontic journal 2025 Aug;58(8):1184-1196

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Protein kinase B inhibitors enhance the sensitivity of translocated promoter region-fibroblast growth factor receptor 1 cells to fibroblast growth factor receptor 1 inhibitor-induced apoptosis.

Lv M, Shangguan W, Zhao Q, Li Y, Zhao Q, Li F
The Journal of international medical research 2025 Aug;53(8):3000605251362968

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Demethylzeylasteral inhibits proliferation and metastasis of osteosarcoma cells by modulating the PI3K/AKT/Autophagy pathways.

Yuan X, Li J, Yu B, Cai F, Chen B, Liu J, Peng Y, Zeng D, Liao Q, Liu L
Journal of bone oncology 2025 Aug;53:100699

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HDAC3 Regulates Ferroptosis via Nrf2-GPX4 Signaling in Colorectal Cancer Cells.

Jin W, Wang JJ, Feng YF, Chen B, Hu ZH
Doklady. Biochemistry and biophysics 2025 Aug;523(1):424-433

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CCL2/CCR4 participates in mast cell-mediated epithelial mesenchymal transition in endometriosis.

Ding S, Mao X, Zhu L, Xu X, Chen S, Zou G, Xu P, Wang J, Zhang X
Reproductive biomedicine online 2025 Aug;51(2):104796

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THEMIS2 contributes to ovarian cancer metastasis via DOCK4-mediated activation of Rap1 signaling.

Zhou K, Ma X, Yan T, Hu L, Tian Y, Zheng H, Xie S, Tong Y, Wang Y, Guo L, Lu R
Cellular oncology (Dordrecht, Netherlands) 2025 Aug;48(4):961-978

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GMPS inhibits the proliferation and migration of non-small cell lung cancer via the regulation of the DNMT 1/SERPINB2 axis.

Guo T, Liu L, Zeng L, Yang Y, Song T, Zhao H, Qiu Z
Cellular oncology (Dordrecht, Netherlands) 2025 Aug;48(4):1145-1158

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PU.1/Spi1 exacerbates ischemia-reperfusion induced acute kidney injury via upregulating Gata2 and promoting fibroblast activation.

Zong C, Xu GL, Ning M, Li JY, Wang X, Guo HJ, Zhang LH, Zhou L, Xu C, Yang ZH, Lu LM, Niu JY
Acta pharmacologica Sinica 2025 Aug;46(8):2251-2266

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SETD5 facilitates stemness and represses ferroptosis via m6A-mediating PKM2 stabilization in non-small cell lung cancer.

Liu X, Cui Y, Gong J, Yu X, Cui Y, Xuan Y
Oncogene 2025 Aug;44(29):2474-2489

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Endoplasmic Reticulum Stress as a Regulator of High Glucose-Induced Epithelial-Mesenchymal Transition in Human Lens Epithelial Cells.

Li H, Yang J
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2025 Aug;41(6):347-354

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Hypercholesterolemia drives microglial dysfunction and weakens response to amyloid plaques.

Kaye S, Gold A, Lin D, Chen M, Zhu J, Gao J
Experimental neurology 2025 Aug;390:115272

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Maternal high fat and high sugar diet impacts on key DNA methylation enzymes in offspring brain in a sex-specific manner.

Hor K, Dearden L, Herzstein E, Ozanne S, Hardingham G, Drake AJ
Journal of neuroendocrinology 2025 Aug;37(8):e70046

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Molecular characterization and functional prioritization of CD46, IL6R, KLRC1, LEAP2 and SMOX as candidate targets in acute kidney injury.

Liu J, Zeng D, Wang Y, Deng F, Deng Z
International journal of biological macromolecules 2025 Aug;320(Pt 4):146096

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Akt-phosphorylated UFL1 UFMylates ArpC4 to promote metastasis.

Zhao K, Hu H, Fang D, Xie M, Chen J, Zhang S, Tang S, Wu M, Guo X, Yu N, Yao B, Jiang W, Wang C, Mei Y
Nature structural & molecular biology 2025 Aug;32(8):1528-1541

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Reduced iron bioavailability drives acute high‑altitude lung injury through HIF1α activation and mitophagy.

Geng Y, Hu Y, Wang H, Zhang F, Ge RL
Molecular medicine reports 2025 Aug;32(2)

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Structural characterization of Morinda officinalis How polysaccharide and its anti-osteoporotic effects via oxidative stress modulation.

Lai H, Liang Y, He L, Guo L, Deng C, Wang X
International journal of biological macromolecules 2025 Aug;319(Pt 4):145616

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The Toxoplasma surface SRS14A promotes ASC ubiquitination to suppress AIM2 inflammasome and tumor immunity.

Yang K, Song Y, Yuan H, Yang Z, He H, Nie L, Mahmmod YS, Zhang XX, Yu M, Yuan ZG
International journal of biological macromolecules 2025 Aug;319(Pt 1):145343

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Immunogenic cuproptosis in cancer immunotherapy via an in situ cuproptosis-inducing system.

Li J, Zhang G, Sun Z, Jiang M, Jia G, Liu H, Liu N, Shi L, Zhang L, Nie L, Zhang Y, Fu Y
Biomaterials 2025 Aug;319:123201

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Manganese dioxide coupled metal-organic framework as mitophagy regulator alleviates periodontitis through SIRT1-FOXO3-BNIP3 signaling axis.

Zhu C, Huang K, Li T, Li Y, Jin Y, Li R, Zhu Z, Yang S, Xia L, Fang B
Biomaterials 2025 Aug;319:123179

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Gastrodin Attenuates Cerebral Ischemia-Reperfusion Injury by Enhancing Mitochondrial Fusion and Activating the AMPK-OPA1 Signaling Pathway.

Liu Z, Han Z, Bao W, Guo Y, Yuan Y, Cheng J, Zhang J, Hu Y
CNS neuroscience & therapeutics 2025 Aug;31(8):e70559

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Metformin promotes PEN2 expression to attenuate microglia-mediated neurotoxicity induced by HIV-1 Tat.

Shen Y, Xu T, Sun Y, Zhang K, Cao X, Shen L, Tang M
Journal of neurovirology 2025 Aug;31(4):376-388

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Leber's hereditary optic neuropathy-associated ND1 3733G>C mutation ameliorates the mitochondrial quality control and cellular homeostasis.

Yasheng M, Ji Y, He Y, Yi Q, Zhang H, Shan W, Wang K, Zhang J, Li Y, Meng F, Zhang M, Mo JQ, Wei S, Guan MX
The Journal of biological chemistry 2025 Aug;301(8):110464

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Subcellular determinants of orthoflavivirus protease activity.

Corliss L, Petit CM, Lennemann NJ
The Journal of biological chemistry 2025 Aug;301(8):110451

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Overexpression of decorin gene influences the biological behaviors of follicular thyroid carcinoma cells.

Lin Q, Ma Y, Guo R, Guo H, Wang X, Yang T
Oncology letters 2025 Aug;30(2):374

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Trojan horse strategy and TfR/ LDLR-Mediated transcytosis determine the dissemination of mycobacteria in tuberculous meningoencephalitis.

Liu Z, Wang Y, Dong Y, Wang H, Liang Z, Yue R, Zhou X
Microbiological research 2025 Aug;297:128172

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A Novel Prognostic Model of Endometrial Cancer Based on Inflammation and Lipid Metabolism Genes.

Zhu L, Zhu H, Zhang Z, Xu F, Zhu Y, Ding K
Genetic testing and molecular biomarkers 2025 Aug;29(8):216-231

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IFI16 Induced by p53 Activates the NF-κB Pathway to Counteract Cisplatin-Induced Apoptosis in Cervical Cancer Cells.

Zhong L, Li J, Zhong J, Zhang Y, Qi H, Yu H, Li X
Journal of cellular and molecular medicine 2025 Aug;29(15):e70728

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PIMREG modulation of PI3K/Akt pathway enhances sorafenib resistance in Huh7 cells.

Zhang L, Gao A, Peng K
Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology 2025 Aug;26(3):241-249

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RASGEF1C affects aerobic glycolysis and facilitates lung cancer progression through the PLK1 signaling pathway.

Wu H, Zheng K, Han F
Expert review of anticancer therapy 2025 Aug;25(8):961-971

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Single-Cell RNA-Seq Reveals Aging-Related Impairment of Microglial Efferocytosis Contributing to Apoptotic Cells Accumulation After Retinal Injury.

Liu P, Wang Q, Wang S, Liu Y, Chen Q, Qin W, Liu X, Ye X, Jiao Y, Yuan H, Shao Z
Aging cell 2025 Aug;24(8):e70097

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From stem cells to skin: ADSCP6 peptide's role in transforming scar therapy.

Li J, Zeng S, Zhou B, Yan Q, Sun Y, Chen L, Zhang E, Li J
Biochemical pharmacology 2025 Aug;238:116980

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Combining label-free quantitative proteomics and 2D-DIGE to identify the potential targets of Sini Decoction acting on myocardial infarction.

Feng F, Zhang W, Cao Y, Lv D, Chai Y, Guo D, Chen X
Chinese journal of natural medicines 2025 Aug;23(8):1016-1024

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A TRPV1 agonist from the transcriptome profiling of Dipsastraea rotumana inhibits neuroinflammation in vivo through the NF-κB and MAPK pathways.

Chen H, Xu N, Kam H, Zhao C, Chen Q, Fan G, Siu SWI, Wong CTT, Qiu JW, Cheung AK, Teixeira A, Rádis-Baptista G, Wong PK, Li S, Gong G, Lee SM
Pharmacological research 2025 Aug;218:107837

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AI-driven discovery of brain-penetrant Galectin-3 inhibitors for Alzheimer's disease therapy.

Liu X, Xu J, Zheng S, Yang Y, Xie Y, Liu J, Zhong J, Zhang H, Chen J, Dai C, Wang D, Luo J, Chen X, Zhong F, Ye ZC
Pharmacological research 2025 Aug;218:107834

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Gut-derived bacterial vesicles carrying lipopolysaccharide promote microglia-mediated synaptic pruning.

Zhao X, Yu J, Xu B, Xu Z, Lei X, Han S, Luo S, Zhang C, Peng G, Li J, Yu J, Ling Y, Fan Z, Mo W, Yang Y, Zhang J
Alzheimer's & dementia : the journal of the Alzheimer's Association 2025 Aug;21(8):e70331

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TFDP1 activates SPC25-mediated glutamine metabolism to repress anti-tumor immunity of NK cells in lung adenocarcinoma.

Huang B, Chen K, Huang M, Yin Z, He W, Peng X, Wu G, Ding J, Peng C, Wu X
Expert review of clinical immunology 2025 Aug;21(8):1171-1181

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Purinergic P2X7 receptor involves in anti-retinal photodamage effects of berberine.

Ye SS, Wang JN, Zhao YF, Dai LS, Zhang JZ, Zuo YQ, Song JT
Purinergic signalling 2025 Aug;21(4):675-685

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Spatiotemporal Immunomodulation of Macrophages via NLRP3/IL-1β Pathway by Core-Shell Microneedles to Promote Healing of Biofilm-Infected Diabetic Ulcers.

Yang Y, Chen N, Fan J, Fan L, Cai Y, Xue L, Chen S, Yang Z, An L, Cheng J, Ren T, Li Y
Small (Weinheim an der Bergstrasse, Germany) 2025 Aug;21(32):e2505179

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The atypical KRAS(Q22K) mutation directs TGF-β response towards partial epithelial-to-mesenchymal transition in patient-derived colorectal cancer tumoroids.

Mair T, König P, Mijović M, Kalla J, Baskan A, Tran L, Draganić K, Saldaña PM, Pérez Malla CU, Pfneissl J, Tiefenbacher A, Kabiljo J, Atanasova VS, Wozelka-Oltjan L, Müllauer L, Bergmann M, Sheibani-Tezerji R, Egger G
Molecular oncology 2025 Aug;19(8):2212-2232

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The role of FLVCR1 and FLVCR2 in choline transport in the Caco-2 intestinal epithelial cell model and rat small intestine.

Yasujima T, Namba C, Azuma Y, Shinoda Y, Matake I, Yamasaki M, Morimoto H, Namai M, Kusuhara H, Inoue K, Yamashiro T, Yuasa H
Biochimica et biophysica acta. Molecular basis of disease 2025 Aug;1871(6):167883

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Hexokinase 2-driven aerobic glycolysis modulates YAP1 in placental trophoblast development.

Zhao C, Zhou H, Wang P, Zhang S, Lin X, Pan Y, Zhu H
Biochimica et biophysica acta. Molecular basis of disease 2025 Aug;1871(6):167872

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TSPO participates in the pathogenesis of diabetic periodontitis related to mitophagy.

Jin W, Lu D, Wei W, Wang M, Chen R, Yan F, Li Y
Biochimica et biophysica acta. Molecular basis of disease 2025 Aug;1871(6):167866

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Differential roles of the ADAM9/NF-κB and the ADAM9/STAT3 feedback loops in HIV-1 Tat-induced microglial inflammatory response and subsequent neuronal apoptosis.

Qiao X, Wei H, Sun W, Ruan C, Cao D
Biochimica et biophysica acta. Molecular basis of disease 2025 Aug;1871(6):167831

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Platelet-rich plasma-derived exosomes have the novel ability to alleviate insertional Achilles tendinopathy by promoting tenogenesis in tendon stem/progenitor cells.

Zhang AY, Xie QZ, Guo SZ, Liu X, Yu YH, Tang H, Yao H, Guo L, Xu SB, Bian XT, Tao X
Biomaterials advances 2025 Aug;173:214272

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The β2-adrenergic receptor modulates activity of porcine alveolar macrophages in response to Actinobacillus pleuropneumoniae infection.

Xing W, Shi H, Wu W, Lu S, Fu H, Lu J, Li S, Xu B
Developmental and comparative immunology 2025 Aug;169:105420

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Structurally diverse neolignans from the root bark of Magnolia officinalis Rehd. et Wils with their bioactivities.

Tang B, Sun J, Zhang S, Zhang L, Li C, Zang Y, Tao X, Zhang J, Ma J, Zhang D
Bioorganic chemistry 2025 Aug;163:108699

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Macrophage DGKζ-mediated phosphatidic acid remodeling aggravates acute liver failure.

Miao Y, Lin T, Wang B, Xu J, Li C, Li Z, Zhang X, Zhou C, Aji T, Tan M, Aisa HA, Li J
Acta pharmaceutica Sinica. B 2025 Aug;15(8):4078-4095

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Kangquan formula ameliorates the benign prostatic hyperplasia induced by testosterone propionate in rats by regulating urine microecology and metabolic profile.

Li CC, Zeng D, Tang HL, Li XM, Luo YH, Lin J, Xi SY, Wen L, Huang YP
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Aug;144:156931

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Nitrate protects against methotrexate-induced liver injury by activating Wnt/β-catenin Signaling in mice.

Wen X, Liu Y, Zhang C, Wang J, Sun G, Zhang D, Wang S, Li S
Toxicology research 2025 Aug;14(4):tfaf107

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Cadmium induces autophagy via IRE1 signaling pathway activated by Ca(2 +) in GC-2spd cells.

Han Y, Dai J, Cheng J, He Y, Zhao C, Li R, Zhang Y, Zhang L, Zhou T, Shi Y
Reproductive toxicology (Elmsford, N.Y.) 2025 Aug;135:108950

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Oxidized-LDL aggravates renal injury via tubular cuproptosis.

Sun DQ, Zhong MY, Zhang JH, Tang H, Hu B, Shen JQ, Yan F, Xu XY, Chen K, Targher G, Byrne CD, Zheng MH, Zhao J, Wang RF
Cellular signalling 2025 Aug;132:111839

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Biliverdin alleviates cerebral ischemia-reperfusion injury by regulating the P4hb/MAPK/mTOR pathway to inhibit autophagy.

Jiang H, Bai W, Yang Y, Zhou G, Li J, Li X, Wan X, Shao J
Cellular signalling 2025 Aug;132:111815

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Hedgehog pathway inhibitor HhAntag suppresses virus infection via the GLI-S1PR axis.

Zhang J, Dong C, Chen Z, Hua R, Li Z, Lin Y, Wang Y, Feng T, Dai J
Cellular signalling 2025 Aug;132:111807

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Isoform specific regulation of osteopontin by AKT2 in hepatocytes and livers.

Slarve I, Wang Y, Ding Y, Niu X, Tang Q, Jia C, Tu T, Hong H, Zhang G, Gu Y, Xu Z, Skinner S, He L, Hua B, Nguyen P, Zhou Y, Chen L, Ashouri K, Martynova A, Nakhoul C, Rastegarpour A, Alachkar H, Lenz HJ, El-Khoueiry A, Sher L, Chopra S, Yuan L, Stiles BL
Cellular signalling 2025 Aug;132:111799

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Annexin A2 binds the 3'-UTR of H2AX mRNA and regulates histone-H2AX-derived hypoxia-inducible factor 1-alpha activation.

Zhang S, Wang YS, Li Y, To KI, Zhang ET, Jin YH
Cellular signalling 2025 Aug;132:111781

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Spatial Domain-Based Approach to Analyze the Mechanism of Sparganii Rhizoma-Curcumae Rhizoma Pair in the Treatment of Colorectal Cancer.

Liu YJ, Ye QW, Jin YL, Zhang Q, Zou X, Li JP
Food science & nutrition 2025 Aug;13(8):e70794

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USF1-activated hsa_circ_0076691 induces oxaliplatin resistance via facilitating FGF9 expression in miR-589-3p-dependent manners.

Tang L, Deng X, Guan M, Zhong L
Non-coding RNA research 2025 Aug;13:15-28

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NIR Driven Pd/Cerium Oxide Nano-Heterojunction for Enhanced Salvaging Sepsis Induced Acute Liver Injury via Reprogramming Redox Homeostasis in Synergy with Inducing Autophagy.

Qin T, Qin L, Zhao Y, Chen Y, Liu Q, Lin X, Lan Y, Huang Y, Liu Y, Zhang K, Pan L, Li J, Duan K, Liang H, Yin M, Fan G, Liu L, Deng Y, Liao L, Su D, Gao M, Lu J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(32):e17252

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Nephronectin (NPNT) is a Crucial Determinant of Idiopathic Pulmonary Fibrosis: Modulating Cellular Senescence via the ITGA3/YAP1 Signaling Axis.

Guo J, Wang Y, Liu Q, Luo Z, Tian X, Wang Y, Liu Y, Ning Z, Guo Y, Gao H, Wang X, Feng J, Liu M, Saifullina D, Zhang Y, Pan T, Bian Y, Ban T, Li T, Gu Y, Liang H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(32):e01956

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Astrocytic ET-1 System Determines Microglia Phenotype Following Spinal Cord Injury.

He B, Xu S, Li M, Li H, Li S, Niu L, Song H, Cai R, Zhou Y, Cao Z, Wang Y, Wang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(31):e07215

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RSPO2 Coordinates with GDF9:BMP15 Heterodimers to Promote Granulosa Cell and Oocyte Development in Mice.

Wang Y, Li H, You L, Wang S, Bie J, Su Z, Shi L, Su YQ
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(30):e01973

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Targeting GPX4 to Induce Ferroptosis Overcomes Chemoresistance Mediated by the PAX8-AS1/GPX4 Axis in Intrahepatic Cholangiocarcinoma.

Chen ZW, Shan JJ, Chen M, Wu Z, Zhao YM, Zhu HX, Jin X, Wang YX, Wu YB, Xiang Z, Ding ZW, Lin ZH, Wang LR, Wang L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(30):e01042

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RONIN/HCF1-TFEB Axis Protects Against D-Galactose-Induced Cochlear Hair Cell Senescence Through Autophagy Activation.

Wei Y, Zhang Y, Cao W, Cheng N, Xiao Y, Zhu Y, Xu Y, Zhang L, Guo L, Song J, Sha SH, Shao B, Ma F, Yang J, Ying Z, He Z, Chai R, Fang Q, Yang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(29):e2407880

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Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia-Inducible Factor-1 Signaling Pathway.

Zhao LN, Wang RL, Liu RX, Zheng MR, Zhao L, Li BF, Li JL, Liu DS, He XX, Peng QB, Li K, Lin TX, Liu YY, He SP, Lu J, Zheng SY, Liu X, Huang FZ
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(29):e17128

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DNA Origami-Based CD44-Targeted Therapy Silences Stat3 Enhances Cartilage Regeneration and Alleviates Osteoarthritis Progression.

Lv Q, Zhao X, Teng S, Jin X, Zhou Y, Sun Y, Pei H, Yan Z, Ma C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(29):e03939

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Novel ATR/PARP1 Dual Inhibitors Demonstrate Synergistic Antitumor Efficacy in Triple-Negative Breast Cancer Models.

Gao Y, Zhou J, Wang CC, Wang ZH, Mao ND, He ML, Zhang PP, Huang P, Ye GW, Zhang YQ, Tang FH, Zhang H, Xie T, Ye XY
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(29):e01916

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SOX15 Transcriptionally Decreases the Level of MMP2 and Inhibits Vasculogenic Mimicry to Slow Down the Progression of Ovarian Cancer.

Zhao X, Wang X, Wang C, Tian H, Zhou Y, Gong L
Biology of the cell 2025 Aug;117(8):e70031

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CGGBP1 from higher amniotes restricts cytosine methylation and drives a GC-bias in transcription factor-binding sites at repressed promoters.

Kumar P, Morbia I, Satish AL, Datta S, Singh U
Transcription 2025 Aug-Oct;16(4-5):285-320

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PGC1α regulates the mitochondrial metabolism response to cyclic stretch, which inhibits neointimal hyperplasia.

Zou M, Ye K, Yan J, Zhang S, Bao H, Li Z, Tao Y, Zhang X, Tian W, Qi Y, Huo Y, Han Y
Cellular and molecular life sciences : CMLS 2025 Aug 8;82(1):303

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Regulation of cortical neurogenesis by MED13L via transcriptional priming and its implications for MED13L syndrome.

Li J, Hao YZ, Cui J, Cao XX, Wu N, Ma J, Xie SY, Pan YH, He XL, Zhao YL, Yuan XB
Communications biology 2025 Aug 8;8(1):1180

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Robo4 inhibits neovascularization in oxygen-induced retinopathy by regulating ARF6 and VEGF.

Liao Y, Yu C, Xiong W, Yin X
Human cell 2025 Aug 8;38(5):140

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In situ-formed immunotherapeutic hydrogel containing sphingosine-1-phosphate for enhanced lung cancer immunotherapy.

Shen H, Deng Q, Chen Z, Zhang Q, Zhou X, Chen Q, Fan J
Science advances 2025 Aug 8;11(32):eadw5001

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NAT10-mediated ac4C modification of Lipin1 mRNA contributes to the pathogenesis of PWMI.

Li X, Zhang M, Liu Y, Guo C, Liu Y, Han L, Feng Z, Wei X, Yao R
JCI insight 2025 Aug 8;10(15)

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Isoimperatorin, a natural furanocoumarin, ameliorates ulcerative colitis by inducing Treg cell generation and promoting mucosal healing.

Fang Y, Min S, Chen H, Zhu Z, Li Y, Tong Y, Hu J, Zhu L, Shen H
Molecular medicine (Cambridge, Mass.) 2025 Aug 7;31(1):275

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PABPC1 SUMOylation enhances cell survival by promoting mitophagy through stabilizing U-rich mRNAs within stress granules.

Huang C, Huang J, Lu R, Yu AJ, Yu AS, Cao Y, Li L, Li J, Li H, Zhou Z, Zhang Y, Xu A, Chen R, Wang Y, Zhao X, Huang J, Fu Y, Xu M, Zhang H, Yu J
Nature communications 2025 Aug 7;16(1):7308

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ATF3 mediates high-salt diet-induced exacerbation of ischemic stroke: therapeutic potential of theta-burst stimulation.

Yu Y, Shi Y, Hu Z, Pang J, Wang X, Liu S, Xie Y, Wu W
Neuroscience 2025 Aug 6;580:124-138

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Neurotensin receptor1 signaling promotes progression of epithelial-mesenchymal transition in mice with chronic rhinosinusitis through Wnt3a/β-catenin pathway.

Wu Y, Zhu X, Gu H, Fu F, Guo Q, Liu K, Yang M, Zhang T, Wang X
Journal of molecular histology 2025 Aug 6;56(4):253

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Glutamate-cysteine ligase as a diagnostic biomarker and therapeutic target in Parkinson's disease: a multi-omics and experimental study.

Li X, Wang M, Zhong C, Xia J, Tian L, Wang J, Yang D
European journal of medical research 2025 Aug 6;30(1):721

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Triptolide targets PPP2CA/ITGA5 axis to suppress lactate-driven ovarian cancer progression.

Ding L, Chen W, Luo C, Weygant N, Lai Y, Ru D, Liu H, Wang Y, Li H
Chinese medicine 2025 Aug 6;20(1):122

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Targeting Msx2 as a brake in the fusion fate of osteoclasts and an anabolic therapy in pre-clinical models of osteoporosis.

Ma Q, Wang S, Xue H, Ni L, Yuan P, Shen Y, Zheng B, Wang Q, Zhang J, Wang H, Xie H, Jiang C, Qin A, Fan S, Xie Z, Jie Z
Nature communications 2025 Aug 6;16(1):7228

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Exosomal miR-218 secreted from endothelial progenitor cells mitigates acute lung injury in sepsis mice by inhibiting HMGA1 in alveolar macrophages.

Liang G, Zeng M, Wang Q, Wang W, Liu J, Gao M, He Z
Stem cell research & therapy 2025 Aug 6;16(1):431

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SIK2 Drives Pulmonary Fibrosis by Enhancing Fibroblast Glycolysis and Activation.

He J, Dong R, Yue H, Zhang F, Dou X, Li X, Li H, Zhang H
Biomedicines 2025 Aug 6;13(8)

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Arachidonic acid triggers spermidine synthase secretion from primary tumor to induce skeletal muscle weakness upon irradiation.

Zhang X, Nie Z, Wang S, Ma Y, Han D, Hu T, Liu L, Men L, Zhang T, Wu X, Li X, Hu S, Yuan M, Liu L, Wang C, Xu P, Xiang L, Liu J, Zhang Y, Zhu D, Lei H, Zhang L, Li X, Zhao Y, Yan W
Cell metabolism 2025 Aug 5;37(8):1766-1782.e12

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Bioinformatics analysis of Rho-signal transduction genes in postmenopausal osteoporosis and periodontitis.

Qi J, Liu E, Pang Y, Wang Y, Wang J
Scientific reports 2025 Aug 5;15(1):28479

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Inhibition of ferroptosis in inflammatory macrophages alleviates intestinal injury in neonatal necrotizing enterocolitis.

Shen L, Chen J, Tou J
Cell death discovery 2025 Aug 5;11(1):365

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Inhibition of UCH-L1 enhances immunotherapy efficacy in triple-negative breast cancer by stabilizing PD-L1.

He L, He J, Jiang T, Gong R, Wan X, Duan M, Chen Z, Cheng Y
European journal of pharmacology 2025 Aug 5;1000:177743

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Analysis of chemical and blood transition components of Xipayi Maizibizi Oral Liquid and its excitatory purine regulation-mechanism study in treating overactive bladder.

Wang M, Yang Y, Xie J, Du Y, Zhao Y, An Y, Shan Z, He C, Fu W, Huang Y, Zhang H, Zhao B
The Journal of pharmacy and pharmacology 2025 Aug 4;77(8):1023-1041

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Trimethylamine N-oxide Induced Chronic Kidney Injury by Triggering PANoptosis.

Shao D, Bai L, Chen Q, Chen Y, Qiu Z, Liu Y, Jin S, Wu Y, Dai J
Physiological research 2025 Aug 31;74(4):613-622

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Identification of the role of ARG1 in the fibrotic process of benign airway stenosis using bioinformatics analysis.

Chen Y, Xu C, Shi D, Yang C, Tong S, Qin Y, Zhang W, Li X, Tian S, Dong Y, Shi H, Bai C
Journal of thoracic disease 2025 Aug 31;17(8):5639-5653

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Bioactive compounds in the modulation of oxidative stress in monocytes and macrophages.

Kushwaha R, Alugoju P, Anthikapalli NVA, Sharma R, Sedlářová M, Pospíšil P, Tamasi G, Bonechi C, Rossi C, Prasad A
Scientific reports 2025 Aug 31;15(1):32012

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Facilitation of natural killer T-cell cytotoxic activity in uterine sarcoma via the CKS2-PI3K-AKT-MICA axis.

Du Y, Lan T, Liu M, Wu W, Ma J
Translational cancer research 2025 Aug 31;14(8):5045-5058

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Tumor-educated platelet RNA as a diagnostic biomarker for ground-glass opacity-related lung adenocarcinoma.

Shao M, Cao J, Wang R, Liu Y, Hu Y, Lei W, Wang L, Liu W
Translational lung cancer research 2025 Aug 31;14(8):3090-3106

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Dysregulation of hsa-mir-10a-5p modulates RNF186 and contributes to ulcerative colitis pathogenesis.

Guo Y, Wu H, Wang L, Miao X
Molecular biology reports 2025 Aug 30;52(1):857

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Pyroptosis-responsive microspheres modulate the inflammatory microenvironment to retard osteoporosis in female mice.

Lu S, Cao J, Song Z, Gong F, Yang P, Ge J, He Y, Han Z, Hou G, Zhang Z, Yang Y, Teng Y, Zhang Z, Zou J, Cheng L, Yang H
Nature communications 2025 Aug 30;16(1):8127

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Evidence that mitochondria in macrophages are destroyed by microautophagy.

Lu SL, Chen S, Noda K, Li Y, Tsai CY, Omori H, Kato Y, Zhang Z, Chen B, Tokuda K, Zheng T, Wakita M, Hara E, Fukuda M, Wada Y, Morita E, Uzawa N, Murakami S, Noda T
Nature communications 2025 Aug 30;16(1):8123

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SPANXB1 drives brain metastasis in breast cancer via MMP1 regulation: potential therapeutic insights with metformin.

Wang Q, Wu H, Zhai Z, Fang D, Yang C, Liu L, Jia X, Du B, Lyu Y, Zhang M, Lu T, Wang L, Gao Y
Cell death discovery 2025 Aug 30;11(1):418

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Mechanisms and synergistic effects of the active components of Xanthocerais lignum in inhibiting rheumatoid arthritis through the modulation of the biological behavior of synovial cells.

Qian H, Bai C, Jia X, Yang Y, Tian X, Wang X
Journal of ethnopharmacology 2025 Aug 29;352:120200

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Xiaoyaosan alleviates chronic psychological stress-induced TH17/Treg imbalance via modulation of the FKBP5/NF-κB axis.

Zhang Y, Luo XR, Zhou YH, Xue QY, Wu SY, Xu JY, Li GH, Liu BP, Zhang MJ, Tong GD, Ao HQ, Liao MM
Journal of ethnopharmacology 2025 Aug 29;352:120184

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LONP1 Promotes Hepatocarcinogenesis by Degrading ACO2 to Alleviate Ferroptosis.

Zhong Y, Wu L, Peng Z, Mao W, Wang T, Wu B, Yu Z, Li X, Chen E
Frontiers in bioscience (Landmark edition) 2025 Aug 29;30(8):41226

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In vivo manipulation of the protein homeostasis network in rhabdomyosarcoma.

Kwong K, Pan Y, Morales J, Watson M, Allegakoen DV, Lee AG, Bivona TG, Wipf P, Guerriero CJ, Brodsky JL, Sabnis AJ
Oncotarget 2025 Aug 29;16:681-696

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Sex-Specific Differences in the Revascularization of Grafted Pancreatic Islets.

Wrublewsky S, Widmann AV, Bickelmann C, Rafacho A, Roma LP, Laschke MW, Ampofo E
Cells 2025 Aug 29;14(17)

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Dynamic changes in intestinal microbiota mediate mechanical hyperalgesia in surgical menopause model: a potential mechanism of DRG neuroinflammation.

Zhao Y, Gong N, Wang S, Yuan Q, Chen X, Li B, Zhang L, Li W, Zhu R, Zhang J, Zhang W
International immunopharmacology 2025 Aug 28;161:115098

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C1q/TNF-related protein-9 promotes diabetic wound healing by enhancing dendritic cell efferocytosis via the ATF3/SLC7A11 signaling axis.

Zhang S, Li L, Li J, Ruan S, Zuo A, Lei S, Guo Y
International immunopharmacology 2025 Aug 28;161:115056

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Pyrazolamide derivative T1 inhibits hepatocellular carcinoma cell proliferation through MAPK pathway modulation.

Zhang Y, Chen Y, Lv H, Wang H, Wang J, Lv X, Zhang M
International immunopharmacology 2025 Aug 28;161:115044

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Panax notoginseng protects blood-retinal barrier by modulating microglia polarization via TLR4/MyD88/NF-κB pathway in endotoxin-induced uveitis.

Peng M, Ning S, Wu Y, Yang M, Zhang Y, Hu T, Yuan Y, Zhang Y, Hao G, Han J
International immunopharmacology 2025 Aug 28;161:114977

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DEK Interacts with IRE1α to Modulate Endoplasmic Reticulum Stress in Deoxynivalenol-Induced Intestinal Inflammation.

Zeng L, Yu D, Xu J, Qu Z, Wu S, Guo C, Wang K, Lin Z, Lin R, Wen J, Deng Y
Journal of agricultural and food chemistry 2025 Aug 27;73(34):21609-21620

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Vinburnine potentiates anti-PD1 immunotherapy in melanoma through IL-24 secretion via P38/MAPK/ATF3 signaling.

Zhu S, Zhang X, Liu W, Zhou Z, Xiong S, Chen X, Peng C
Journal of experimental & clinical cancer research : CR 2025 Aug 27;44(1):255

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CFP1 promotes germinal center affinity maturation and restrains memory B cell differentiation through H3K4me3 modulation.

Zhao Y, Gong S, Yang Y, Lu Y, Bai J, Liu M, Bai W, Dong J
Nature communications 2025 Aug 27;16(1):8013

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Remodeling adipocytes' lipid metabolism with a polycation loaded enzyme-active framework reverses osteoporotic bone marrow.

Lin W, Gu S, Zhang X, Li K, Zhao D, Ma B, Pan C, Xu Z, Liu T, Wang H, Hu S, Chen H
Nature communications 2025 Aug 27;16(1):8009

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DHRS9 promotes malignant progression of ovarian cancer through SQSTM1.

Wu Y, Meng S, Zhao H, Tan B, Gao J, Du J, Meng X
Journal of cancer research and clinical oncology 2025 Aug 27;151(8):236

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Mitochondrial Phosphopantetheinylation is Required for Oxidative Function.

Norden PR, Wedan RJ, Preston SEJ, Canfield M, Graber N, Longenecker JZ, Pentecost OA, McLaughlin E, Hart ML, Nowinski SM
bioRxiv : the preprint server for biology 2025 Aug 27;

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Protein lactylation of citrate synthase promotes the AKI-CKD transition by activating the NLRP3 inflammasome.

Yu F, Meng Y, Wang X, Chen J, He J, Yi X, He Y, Chen K
Cell reports 2025 Aug 26;44(8):116084

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Hybrid-Ligand Metal-Organic Frameworks Enabling Radio-Radiodynamic-Chemodynamic Therapy Primes Checkpoint Blockade Immunotherapy in Hypoxic Tumors.

Zhai S, You Z, Li J, Zheng B, Zhao X, Jiang W, Su D, Wang H, Han C, Lu K
ACS nano 2025 Aug 26;19(33):30100-30114

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β-Nicotinamide mononucleotide protects against hypervirulent Klebsiella pneumoniae bloodstream infection and liver injury.

Cao Z, Meng B, Chen J, Ge R, Liu Y, Li J
mSphere 2025 Aug 26;10(8):e0036125

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Targeting and Suppression of Survivin in Cancer Cells Based on the Interaction of Cell Surface Vimentin with N‑Acetylglucosamine-Bearing Polymers.

Kitagawa K, Kobayashi S, Miura Y, Tanaka M, Ise H
ACS omega 2025 Aug 26;10(33):37162-37175

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Paris saponin VII restrains PD-L1 mediated immune evasion through the AKT1 and STAT3 signaling pathways.

Wang Y, Li Y, Zhang Y, Li Y, Zhao L, Tong L, Zhu X, Wang J, Dong Y
Chemico-biological interactions 2025 Aug 25;417:111562

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Beneficial Effects of Different Types of Exercise on Diabetic Cardiomyopathy.

Ma X, Gao H, Wang Z, Zhu D, Dai W, Wu M, Guo Y, Zhao L, Xiao W
Biomolecules 2025 Aug 25;15(9)

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Harnessing dual-channel probiotics to synergistically correct intestinal and vaginal dysbiosis after antibiotic disruption.

Zhao X, Huang Q, Liu Y, He X, Chen W, Liu Y, Gan L, Wei J, Zhang H, Chen T
NPJ biofilms and microbiomes 2025 Aug 25;11(1):174

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NSD1-916aa encoded by CircNSD1 contributes to AKI-to-CKD transition through inducing ferroptosis in tubular epithelial cells.

Gao L, Zhang J, Chen C, Zhu S, Wei X, Tang G, Wang S, Wang Y, Liu X, Jiang L, Wu Y
JCI insight 2025 Aug 22;10(16)

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CircZFR/YTHDF3 axis drives lymph node metastasis in cervical cancer via FASN translation.

Zhou M, Gao Y, Zhang Y, He L, Gao B, Zhang Y, Claret FX, Calin GA, Wang D
Molecular cancer 2025 Aug 21;24(1):218

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MRPL13 enhances mitochondrial function and promotes tumor progression in ovarian cancer by inhibiting mPTP opening via SLC25A6.

Liu O, Hu Y, Wang S, Nie X, Wang Y, Fan X, Zeng K, Li X, Liu B, Lin B
Cell death & disease 2025 Aug 21;16(1):634

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GDNF attenuates a-synuclein aggregation-induced damage to VTA-NAc dopaminergic transmission and alleviates depression-like behaviors in mice.

Chen J, Ling Z, Lv M, Chen S, Xu W, Shao L, Ma Z, Wang C, Song Y, Tang C
Scientific reports 2025 Aug 21;15(1):30804

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Adipocyte-derived IL6 and triple-negative breast cancer cell-derived CXCL1 co-activate STAT3/NF-κB pathway to mediate the crosstalk between adipocytes and triple-negative breast cancer cells.

Ruan GT, Zhu LC, Xie HL, Zhang HY, Song MM, Deng L, Shi HP
Cell death discovery 2025 Aug 21;11(1):395

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The γ-Actin with pathogenic variants of sites on actin-binding proteins caused earlier onset and more malignant progressive hearing loss.

Li S, Feng Q, Mei L, Zhang S, Song J, Feng Y, Wu X
Journal of medical genetics 2025 Aug 20;62(9):581-591

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[Haematococcus pluvialis alleviates bleomycin-induced pulmonary fibrosis in mice by inhibiting transformation of lung fibroblasts into myofibroblast].

Zhang X, Man J, Zhang Y, Zheng Y, Wang H, Yuan Y, Xie X
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2025 Aug 20;45(8):1672-1681

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Sanren decoction ameliorates ulcerative colitis by modulating gut microbiota and macrophage polarization to enhance intestinal barrier function.

Zhang S, Li B, Han X, Ruan L, Fu X, Chen Y, Wan H, Zhu X, Liu D, Yi B
Chinese medicine 2025 Aug 20;20(1):128

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Endothelial delivery of simvastatin by LRP1-targeted nanoparticles ameliorates pathogenesis of alzheimer's disease in a mouse model.

Pan TT, Sun YY, Shi YF, Zhao M, Khan NU, Chen HY, Ji WL, Li J, Han L, Ma QH
Alzheimer's research & therapy 2025 Aug 20;17(1):193

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Systematic screening for functional exon-skipping isoforms using the CRISPR-RfxCas13d system.

Sun Q, Ma X, Ning Q, Li S, Wang P, Tan X, Jin Q, Zheng J, Li Y, Dong D
Cell systems 2025 Aug 20;16(8):101351

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Flavonoids from Ficus pandurate var. angustifolia W.C. Cheng Restore Cognitive Impairment and Regulate the Gut Microbiota in Sleep-Deprived Mice.

Dai H, Luo S, Zhang X
Foods (Basel, Switzerland) 2025 Aug 20;14(16)

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CAFs exosomal miR-21-5p suppresses ferroptosis and promotes proliferation and migration in osteosarcoma.

Niu X, Tian W, Ke Y, Li Y, Zhang X
Cancer cell international 2025 Aug 19;25(1):308

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Clonorchis sinensis-driven hepatocarcinogenesis via E2F1-CD24 transcriptional axis: mechanistic and therapeutic implications.

Lu WM, Yan J, Liu ZJ, Wu Y, Cui QR, Feng J, Chen Y, Zhu GZ, Peng T, Zhou J, Lu GD
Parasites & vectors 2025 Aug 19;18(1):353

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Noncanonical function of Pannexin1 promotes cellular senescence and renal fibrosis post-acute kidney injury.

Huang L, Shen Y, Pan X, Li J, Li C, Ruan L, He S, Huang L, Liu K, Zhao X, Geng J, Guo J, Hou FF, Wang J
Nature communications 2025 Aug 19;16(1):7699

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Systematic characterization of cell type-specific master metabolic regulators in Alzheimer's disease.

Qiu Y, Hou Y, Wetzel L, Caldwell JZK, Zhu X, Pieper AA, Liu T, Cheng F
Research square 2025 Aug 18;

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Neutrophil extracellular traps induce fibroblast ferroptosis via IRE1α/XBP1-mediated ER stress to impair diabetic wound healing.

Zhao H, Liu Y
Free radical biology & medicine 2025 Aug 16;236:17-27

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Transcriptomic analysis reveals the impact of Rutin on the proliferation, barrier function, and transcription of Porcine IPEC-J2.

Wang B, Huo L, Tian W, Xing W, Luo G, Li M, Sun L, Liu J
Veterinary research communications 2025 Aug 15;49(5):281

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METTL3 promotes peritoneal metastasis of colorectal cancer through regulating m6A modification of NRXN3 mRNA.

Lan TH, Li W, Wang X, Geng YJ, Pang B, Kang LF, Li DY, Pang LY, Zhang XX, Zhang CQ, Wang GQ, Li ZX, Zhou CM, Jiang X, Zhao ZR
iScience 2025 Aug 15;28(8):113165

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UBE2J2 is essential for the progression of meiosis prophase I during spermatogenesis in mice.

Yu X, Cen J, Zhang Y, Li T, Zhang M, Gao F, Liu H, Cao Y
iScience 2025 Aug 15;28(8):112878

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17β-Trenbolone modulates anxiety-related synaptic plasticity by affecting the interaction between hippocampal TACR3 and systemic testosterone in male mice.

Zuo X, Bai H, Qiu J, Li R, Kuang X, Zhao Y, Tuo J, Zhao Q, Zhao X, Feng X
Environmental research 2025 Aug 15;279(Pt 1):121796

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Investigation of Pharmacological Mechanisms and Active Ingredients of Cichorium intybus L. in Alleviating Renal Urate Deposition via lncRNA H19/miR-21-3p Regulation to Enhance ABCG2 Expression.

An X, Xu Y, Mao Q, Lu C, Yin X, Chen S, Zhang B, Lin Z, Wang Y
International journal of molecular sciences 2025 Aug 15;26(16)

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Targeting lipid scrambling potentiates ferroptosis and triggers tumor immune rejection.

Yang M, Yu Z, Ping J, Duan Y, Tang J, Liu W, He Q, Lai Y, Lam SM, Tang H, Liu Z, Wang W, Zhu M, Hu W, Han Y, Shui G, Hao J, Liu Z, Wu N
Science advances 2025 Aug 15;11(33):eadx6587

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Development of Hydrogen Sulfide-Donating Silybin Derivatives with a Type-2 Diabetes Mellitus-Alleviating Effect through Improving Intestinal L-Cell Functions.

Li H, Ma Q, Li X, Zheng C, Lin L, Gu J, Huang X, Yang H, Xu H, Xu F, Hua H, Cheng M, Li D
Journal of medicinal chemistry 2025 Aug 14;68(15):15520-15542

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Multiple Strategies Confirm the Anti Hepatocellular Carcinoma Effect of Cinnamic Acid Based on the PI3k-AKT Pathway.

Guo J, Yan L, Yang Q, Li H, Tian Y, Yang J, Xie J, Zhang F, Hao E
Pharmaceuticals (Basel, Switzerland) 2025 Aug 14;18(8)

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NSUN2 promotes colorectal cancer progression by stabilizing PHGDH mRNA to promote serine metabolism reprogramming.

Li H, Gong T, Zhao Y, Luo Y, Tang S, Wang T, Lin H, Zhong M
Cancer & metabolism 2025 Aug 14;13(1):37

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GLUT3 enhances chemosensitivity in glioblastoma by transporting temozolomide and capecitabine.

Diao H, Sun Y, Zhou X, Wang Q, Wang M, Chen K, Huang Z, Wei J, Li Z, Lou Y, Mao Z, Yu W
Cell death discovery 2025 Aug 14;11(1):382

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AAV-based gene replacement reverses Neurexin-2 downregulation in the cerebellum of a mouse model of phosphomannomutase 2 deficiency (PMM2-CDG).

Zhong M, Lai K
bioRxiv : the preprint server for biology 2025 Aug 14;

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Mechanisms and clinical translation of ICOS/ICOSL signaling pathway blockade in delaying vascular complications of type 2 diabetes.

Zhang H, Ruan L, Fu X, Yu J, Ruan Q, Li Y, Wang H, Shao H, Dong H, Cui J
Diabetology & metabolic syndrome 2025 Aug 13;17(1):328

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A noncarcinoma mouse cell line is nonsusceptible to Newcastle disease virus established by spontaneous immortalization.

Li H, Zhou Z, Chang C, Shi W, Li Y, Wei Q, Meng F, Tian J, Hao Q, Liu J, Liu H, Yang Z, Xiao S
Scientific reports 2025 Aug 13;15(1):29744

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CD81(+) senescent-like fibroblasts exaggerate inflammation and activate neutrophils via C3/C3aR1 axis in periodontitis.

Fu L, Yin C, Zhao Q, Guo S, Shao W, Xia T, Sun Q, Chen L, Li J, Wang M, Xia H
eLife 2025 Aug 13;13

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2-aminoethoxydiphenylborane intervenes intracellular calcium signaling and attenuates myocardial ischemia-reperfusion injury in mice through ITPR1/MCU pathway.

Bao H, Chen X, Hu X, Cao Z, Zhou W, Chen B, Liao F, Wei F, Huang R, Li W, Chen Z
Scientific reports 2025 Aug 12;15(1):29469

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Exploring the Antitumor Mechanisms of Bai-Hua-She-She-Cao and Ban-Zhi-Lian against Head and Neck Squamous Cell Carcinoma: A Study on Natural Anticancer Therapeutics.

Zhang Y, Pan Y, Wang K
ACS omega 2025 Aug 12;10(31):34528-34538

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Targeting USP2 induces degradation of PML-RARα with or without drug-resistant mutations in acute promyelocytic leukemia.

Zhang J, Wu W, Wang Y, Zhang Y, Wang Y, Bai W, Zhang Z, Zhu C, Wu Y, Zhang Z, Yang L, Lei H, Xu H, Zhou L, Wu Y
Acta biochimica et biophysica Sinica 2025 Aug 11;58(3):574-83

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Moxibustion ameliorates abnormal subchondral bone remodeling by promoting ACSL1-mediated autophagy to degrade NLRP3 in osteoarthritis.

Chen X, Fu L, Huang Y, Liao Q, Zou B, Yuan L, Liu G
Chinese medicine 2025 Aug 11;20(1):125

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TRIM59 suppresses mitochondrial-associated apoptosis to facilitate progression in papillary renal cell carcinoma via the ACAT1-cardiolipin pathway.

Weng H, Zhong J, Yang R, Han B, Kong Q, Zhang Y, Zhuang W, Wang J, Hu H, Lin X
Cell death & disease 2025 Aug 11;16(1):606

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Extremely low-frequency electromagnetic fields facilitate proliferation and functional differentiation in spinal neural stem cells.

Tang W, He D, Li X, Feng Y, Xu Y, Hu J, Xu W, Xue L
Scientific reports 2025 Aug 11;15(1):29291

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PAD2 disturbs cardiomyocyte calcium homeostasis by citrullinating SERCA2a protein in hemorrhagic shock induced arrhythmia.

Gan L, Li R, Wang Q, Zhou J, Zhang M, Leng M, Zhao J, Yang F, Jia S, Huang W, Ye J, Zheng M, Wang T
The journal of trauma and acute care surgery 2025 Aug 1;99(2):219-232

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Recharacterization of the Tumor Suppressive Mechanism of RSL3 Identifies the Selenoproteome as a Druggable Pathway in Colorectal Cancer.

DeAngelo SL, Zhao L, Dziechciarz S, Shin M, Solanki S, Balia A, El-Derany MO, Castillo C, Qin Y, Das NK, Bell HN, Paulo JA, Zhang Y, Rossiter NJ, McCulla EC, He J, Talukder I, Ng BW, Schafer ZT, Neamati N, Mancias JD, Koutmos M, Shah YM
Cancer research 2025 Aug 1;85(15):2788-2804

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CXCR4-Mediated Chemokine Signaling Orchestrates the Progression of Conjunctival Melanocytic Lesions.

Huang Z, Zhu T, Chen J, Qiu M, Rao Y, Jia R, Xu S
Investigative ophthalmology & visual science 2025 Aug 1;66(11):23

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Tumor suppressor OSR1 is modified by SUMO1 and regulates the Wnt/β-catenin signaling pathway in HCC.

Lin X, Liu Y, Lai Z, Wang X, Cui Y, Weng S
Experimental cell research 2025 Aug 1;451(1):114693

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USP18 is a key regulator of immune function in mouse midbrain microglia.

Lu L, Jifu C, Pei B, Gao X, Xu Z, Yin X, Xia J, Wang J
Life sciences 2025 Aug 1;374:123692

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Association of alterations in transcriptomics and intestinal immune responses with Bifidobacterium longum BAA2573 in improving dextran sulfate sodium-induced colitis.

Hao W, Gu L, Zhou R, Huang C, Wang X, Liu Y, Lin Q
BMC gastroenterology 2025 Aug 1;25(1):551

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Mechanistic insights into cadmium-induced nephrotoxicity: NRF2-Driven HO-1 activation promotes ferroptosis via iron overload and oxidative stress in vitro.

Luo T, Song S, Wang S, Jiang S, Zhou B, Song Q, Shen L, Wang X, Song H, Shao C
Free radical biology & medicine 2025 Aug 1;235:162-175

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Identification of NPR2 gene mutations affecting chondrocyte differentiation in short stature through JAK2-STAT5.

Wei S, He M, Zhang C, Li Y, Zhang M, Hou X, Ban B, Zhao Q
Orphanet journal of rare diseases 2025 Aug 1;20(1):392

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Hepatocyte-Enriched miRNA-193b-3p Promotes Hepatitis B Virus Replication by Dual Activation of Viral Core Promoter Activity and Autophagy Induction by Targeting IGF-1R.

Deng Y, Zheng J, Li F, Zou H, Tian S, Zhao Z, Zeng H, Zhai Y, Deng W, Zhang J, Lu M, Jia B, Lin Y
Journal of medical virology 2025 Apr;97(4):e70330

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CD73 alleviates podocytes injury in adriamycin-induced nephrotic syndrome.

Zhu Y, Xie G, Qi F, Tang S, Xun W
Tissue & cell 2025 Apr;93:102647

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NME7 maintains primary cilium assembly, ciliary microtubule stability, and Hedgehog signaling.

Ji M, Cui W, Feng Q, Qi J, Wang X, Zhu H, Zhang W, Fu W
Life science alliance 2025 Apr;8(4)

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Isoliquiritigenin suppresses fatty acid synthesis and cancer cell migration in anaplastic thyroid carcinoma through AMPK/SREBF1 pathway.

Chen L, Fu Y, Wang J, Lv N, Yu S, Fang Q, Xin W
Archives of biochemistry and biophysics 2025 Apr;766:110352

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SOX17 Prevents Endothelial-Mesenchymal Transition of Pulmonary Arterial Endothelial Cells in Pulmonary Hypertension through Mediating TGF-β/Smad2/3 Signaling.

Zou X, Yuan M, Zhou W, Cai A, Cheng Y, Zhan Z, Zhang Y, Pan Z, Hu X, Zheng S, Liu T, Huang P
American journal of respiratory cell and molecular biology 2025 Apr;72(4):364-379

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Synergistic photoinduction of ferroptosis and apoptosis by a mitochondria-targeted iridium complex for bladder cancer therapy.

Zheng J, Zhang A, Du Q, Li C, Zhao Z, Li L, Zhang Z, Qin X, Li Y, Wang KN, Yu N
Journal of colloid and interface science 2025 Apr;683(Pt 1):420-431

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Hexokinase 2 promotes ISGylation of Acyl-CoA synthetase long-chain family member 4 in sepsis-induced microglia cells.

Bai G, Ke S, Lu J, Yu S, Li S, Fang M, Ling J
Journal of lipid research 2025 Apr;66(4):100776

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Porcine epidemic diarrhea virus nsp14 inhibited IFN-Ⅰ production by targeting RIG-I for degradation.

Li S, Wang L, Wen Y, Han J, Hou J, Hou Z, Xie J, Li H, Li X, Yang Y, Feng R
Virology 2025 Apr;605:110451

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NR4A1 suppresses breast cancer growth by repressing c-Fos-mediated lipid and redox dyshomeostasis.

Jiang C, Zhu Y, Zhang J, Chen H, Li W, Xie R, Kong L, Chen L, Chen X, Huang H, Xu S
Experimental & molecular medicine 2025 Apr;57(4):804-819

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Human neuron chimeric mice reveal impairment of DVL-1-mediated neuronal migration by sevoflurane and potential treatment by rTMS.

Zhao Y, Zhao Y, Liang L, Chen A, Li Y, Liu K, Xie R, Mao H, Ren B, Huang B, Shi C, Shao Z, Wu S, Wang Y, Zhang H
Experimental & molecular medicine 2025 Apr;57(4):745-758

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Minor Splicing Factor RNPC3 Is Essential for the Germinal Center B Cell Response.

Wang J, Ruan GX, Li Y, Xiao X, Zhu Z, Chen W, Huang H, Zhang R, Wang R, Chen M, Guo L, Li Y, Xu S, Ou X
European journal of immunology 2025 Apr;55(4):e202451508

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Thymoquinone mitigates cardiac hypertrophy by activating adaptive autophagy via the PPAR‑γ/14‑3‑3γ pathway.

Qiu RB, Zhao ST, Xu ZQ, Hu LJ, Zeng RY, Qiu ZC, Peng HZ, Zhou LF, Cao YP, Wan L
International journal of molecular medicine 2025 Apr;55(4)

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Nrf2 deficiency aggravates hepatic cadmium accumulation, inflammatory response and subsequent injury induced by chronic cadmium exposure in mice.

Chen C, Han X, Xu N, Shen W, Wang G, Jiao J, Kong W, Yu J, Fu J, Pi J
Toxicology and applied pharmacology 2025 Apr;497:117263

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PRMT5 Inhibition Enhances Therapeutic Efficacy of Cisplatin via Mediating miR-29b-3p-Mcl-1 Expression in Lung Adenocarcinoma.

Li H, Fan J, Shen W, Zhang Y, Zhu X, Li P, Gu Z, Jing P
Cell biology international 2025 Apr;49(4):407-418

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Integrative analysis of genetic variability and functional traits in lung adenocarcinoma epithelial cells via single-cell RNA sequencing, GWAS, bayesian deconvolution, and machine learning.

Gao C, Wu J, Zhong F, Yang X, Liu H, Lai J, Cai J, Mao W, Xu H
Genes & genomics 2025 Apr;47(4):435-468

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RNA-binding motif protein RBM39 enhances the proliferation of gastric cancer cells by facilitating an oncogenic splicing switch in MRPL33.

Lu CP, Li JB, Li DB, Wang YH, Jiang XG, Ma JJ, Xu G
Acta pharmacologica Sinica 2025 Apr;46(4):1068-1081

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Discovery of novel dual-target inhibitors of LSD1/EGFR for non-small cell lung cancer therapy.

Wei Y, Sun MM, Zhang RL, Wang L, Yang LH, Shan CL, Lin JP
Acta pharmacologica Sinica 2025 Apr;46(4):1030-1044

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Hypocrellin A from an ethnic medicinal fungus protects against NLRP3-driven gout in mice by suppressing inflammasome activation.

Yan LJ, Qi S, Wu C, Jin R, Hu C, Wang AL, Wang BL, Yu HW, Wang L, Liu J, Qi ZP, Wang WC, Liu QS
Acta pharmacologica Sinica 2025 Apr;46(4):1016-1029

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Synergistic restoration of spinal cord injury through hyaluronic acid conjugated hydrogel-polydopamine nanoparticles combined with human mesenchymal stem cell transplantation.

Kao Y, Song W, Zhang R, Gu G, Qiu H, Shen W, Zhu H, Liu Y, Yang Y, Liu H, Zhang Z, Kong X, Feng S
Bioactive materials 2025 Apr;46:569-581

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Electroacupuncture alleviates insulin resistance and impacts the hypothalamic IRS-1/PI3K/AKT pathway and miRNA-29a-3p in a rat model of type 2 diabetes.

Zhuang S, Liu S, Li R, Duan H
Acupuncture in medicine : journal of the British Medical Acupuncture Society 2025 Apr;43(2):104-113

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The Ameliorative Effect of Betulinic Acid on Oxidative Stress in Mice of Cyclophosphamide-Induced Liver Damage.

Huang Y, Ma C, Zhu L, Kong L, Huang C, Yang W, He J, Yang M, Huang L, Yuan L, Yi J
Environmental toxicology 2025 Apr;40(4):608-623

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Development of a reporter HBoV1 strain for antiviral drug screening and life cycle studies.

Tang J, Chen S, Zhong Y, Deng Y, Huang D, Liu J, Zheng Y, Xu J, Xue B, Wang F, Zhou Y, Wang H, Yang Q, Chen X
Virologica Sinica 2025 Apr;40(2):275-283

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Exploring the anti-NSCLC mechanism of phillyrin targeting inhibition of the HSP90-AKT pathway.

Duan Q, Li R, Wang M, Cui Z, Zhu X, Chen F, Han F, Ma J
Naunyn-Schmiedeberg's archives of pharmacology 2025 Apr;398(4):3789-3802

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miR-484 as an "OncomiR" in Breast Cancer Promotes Tumorigenesis by Suppressing Apoptosis Genes.

Tahtasakal R, Hamurcu Z, Oz AB, Balli M, Dana H, Gok M, Cinar V, Inanc M, Sener EF
Annals of surgical oncology 2025 Apr;32(4):2994-3008

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UC-MSCs based on biomimetic microniche exert excellent regulatory effects on acute brain inflammation through advantageous properties.

Zhao B, Wang C, Sun M, Ma X, Zeng Q, Xi J, Zhou J, Pei X, Jia Y, Yue W
Biomaterials 2025 Apr;315:122945

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Targeted sonodynamic therapy induces tumor cell quasi-immunogenic ferroptosis and macrophage immunostimulatory autophagy in glioblastoma.

Wang MF, Guo J, Yuan SJ, Li K, Zhang Q, Lei HM, Wu JL, Zhao L, Xu YH, Chen X
Biomaterials 2025 Apr;315:122913

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Oxidized Low-Density Lipoprotein Decreases the Survival of Bone Marrow Stem Cells via Inhibition of Bcl-2 Expression.

Li X, Li Y, Yu H, Men LL, Deng G, Liu Z, Du JL
Tissue engineering. Part A 2025 Apr;31(7-8):325-333

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ZNF331 Represses the Proliferation of Head and Neck Squamous Cell Carcinoma via Co-Repressor TRIM28.

Li J, Cheng H, Zhao Y, Wang Y, Gong C, Gong R, Li Y
Oral diseases 2025 Apr;31(4):1178-1188

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CIP2A promotes bronchiolitis obliterans by activating the NF‑κB pathway.

Zhou X, Zhao X, Li Y, Zhang B
Molecular medicine reports 2025 Apr;31(4)

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GOLM1 promotes cholesterol gallstone formation via ABCG5-mediated cholesterol efflux in metabolic dysfunction-associated steatohepatitis livers.

Li YT, Shao WQ, Chen ZM, Ma XC, Yi CH, Tao BR, Zhang B, Ma Y, Zhang G, Zhang R, Geng Y, Lin J, Chen JH
Clinical and molecular hepatology 2025 Apr;31(2):409-425

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An anti-inflammatory and anti-fibrotic Janus hydrogel for preventing postoperative peritoneal adhesion.

Li Z, Yang L, Jin Q, Li W, Li Y, Zheng Y, Dong M, Bian Y
Materials today. Bio 2025 Apr;31:101637

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Mitochondria-targeted photothermal-chemodynamic therapy enhances checkpoint blockade immunotherapy on colon cancer.

Zheng B, Wang H, Zhai S, Li J, Lu K
Materials today. Bio 2025 Apr;31:101542

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Proanthocyanidin capsules remodel the ROS microenvironment via regulating MAPK signaling for accelerating diabetic wound healing.

Wei S, Yang D, Shou Z, Zhang Y, Zheng S, Zan X, Li L, Zhang C
Materials today. Bio 2025 Apr;31:101467

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Lycium ruthenicum Murray exosome-like nanovesicles alleviated Alzheimer's disease-like symptoms induced by Aβ protein in transgenic Caenorhabditis elegans through the DAF-16 pathway.

Zhang Y, Zhang X, Zhou J, Li Y, Kai T, Zhang L
International journal of biological macromolecules 2025 Apr;304(Pt 1):140758

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Acute hyperglycemia impedes spinal cord injury recovery via triggering excessive ferroptosis of endothelial cells.

Wu M, Zhang S, Wu X, Zhou Y, Zhou M, Du A, Zhang Y, Wei T, Wang B, Wang S, Jiang C, Hu S, Xiao J, Wu Y
International journal of biological macromolecules 2025 Apr;301:140453

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Astrocyte-conditional knockout of MOB2 inhibits the phenotypic conversion of reactive astrocytes from A1 to A2 following spinal cord injury in mice.

Tao X, Chen H, Zhu Z, Ren T, Zhen H, Sun X, Song Y, Xu X, Song Z, Liu J
International journal of biological macromolecules 2025 Apr;300:140289

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Subcellular proteomics reveals the crosstalk between nucleocytoplasmic trafficking and the innate immune response to Senecavirus A infection.

Li M, Deng X, Zhou M, Wan H, Shi Y, Zhang L, He W, Zhang Y, Hu M, Du Y, Jiang D, Han S, Wan B, Zhang G
International journal of biological macromolecules 2025 Apr;298:139898

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TRIM21 interacts with IκBα and negatively regulates NF-κB activation in Corynebacterium pseudotuberculosis-infected macrophages.

Wu C, Wang X, Li X, Li H, Peng Q, Niu X, Wu Y, Wang Z, Zhou Z
Veterinary immunology and immunopathology 2025 Apr;282:110910

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Inhibition of glutaminase 1 reduces M1 macrophage polarization to protect against monocrotaline-induced pulmonary arterial hypertension.

Chen X, Li L, Deng Y, Liao J, Meng H, Liang L, Hu J, Xie D, Liang G
Immunology letters 2025 Apr;272:106974

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Taxifolin ameliorates the D-galactose-induced aging of mouse hippocampal neurons HT-22 cells through modulating SIRT1/p53 and PI3K/AKT signaling pathways.

Liu XL, Zu S, Yue H, Li AN, Sun PP, Li JG, Yan L, Ma LN, Zhang S
Journal of Asian natural products research 2025 Apr;27(4):615-631

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Caspase cleavage of influenza A virus M2 disrupts M2-LC3 interaction and regulates virion production.

Figueras-Novoa C, Akutsu M, Murata D, Weston A, Jiang M, Montaner B, Dubois C, Shenoy A, Beale R
EMBO reports 2025 Apr;26(7):1768-1791

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A critical role of N(4)-acetylation of cytidine in mRNA by NAT10 in T cell expansion and antiviral immunity.

Sun L, Li X, Xu F, Chen Y, Li X, Yang Z, Yang Y, Wang K, Ren T, Lin Z, Wang H, Wang X, Lu Y, Song Z, Cheng ZL, Wu D
Nature immunology 2025 Apr;26(4):619-634

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FOXA2 Loss in TGF-β1-Induced EMT Suppresses Bisecting-GlcNAc N-Glycan Synthesis in Lung Adenocarcinoma.

Ge W, Wen S, Zhou X, Chen Y, Zeng D, Jiang J, Yang S
Proteomics 2025 Apr;25(8):e202400216

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Diagnostic value and immune infiltration characterization of WTAP as a critical m6A regulator in liver transplantation.

Li SS, Lei DL, Yu HR, Xiang S, Wang YH, Wu ZJ, Jiang L, Huang ZT
Hepatobiliary & pancreatic diseases international : HBPD INT 2025 Apr;24(2):138-146

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N6-methyladenosine-mediated EIF3H promotes anaplastic thyroid cancer progression and ferroptosis resistance by stabilizing β-catenin.

Zhang Z, Zhou D, Qiu X, Xia F, Li X
Free radical biology & medicine 2025 Apr;231:38-47

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Chlorogenic acid improves SPS-induced PTSD-like behaviors in rats by regulating the crosstalk between Nrf2 and NF-κB signaling pathway.

Tang C, Gao J, Li S, Cheng H, Peng YY, Ding Y, Yang H, Ma XM, Wang HY, Long ZY, Lu XM, Wang YT
Free radical biology & medicine 2025 Apr;231:136-152

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Total alkaloids from Thesium chinense inhibit lipopolysaccharide-induced respiratory inflammation by modulating Nrf2/NF-κB/NLRP3 signaling pathway.

Li G, Guan Y, Xu L, Peng G, Han Q, Wang T, Xu Z, Wen X, Lou H, Shen T
Chinese journal of natural medicines 2025 Apr;23(4):421-430

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Design, Synthesis, and Biological Evaluation of Naphthalimide-Polyamine Conjugate as a Potential Anti-Colorectal Cancer Agent.

Dai F, Cao Y, Zhu C, Li Y, Ma X, Wang S, Liu H, Xie X, Gao L, Wang Y, Wang C
Chemistry & biodiversity 2025 Apr;22(4):e202401873

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β-hydroxybutyrylation and O-GlcNAc modifications of STAT1 modulate antiviral defense in aging.

Zuo Y, Wang Q, Tian W, Zheng Z, He W, Zhang R, Zhao Q, Miao Y, Yuan Y, Wang J, Zheng H
Cellular & molecular immunology 2025 Apr;22(4):403-417

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Fusaric acid-mediated S-glutathionylation of MaAKT1 channel confers the virulence of Foc TR4 to banana.

Zhang J, Liu S, Yang W, Xie Y, Shao C, Zhang ZR, Li C, Yao X
PLoS pathogens 2025 Apr;21(4):e1013066

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Selenium nanoparticles attenuate retinal pathological angiogenesis by disrupting cell cycle distribution.

Nie Z, Liu Y, Xu L, Wang Y, Wang M, Zhou W, Zhu H, Zhao M, Wang S, Zhang H, Geng M, Peng M, Zeng H, Zhang Y, Zhu P, Shen W
Nanomedicine (London, England) 2025 Apr;20(8):803-816

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Customizable virus-like particles deliver CRISPR-Cas9 ribonucleoprotein for effective ocular neovascular and Huntington's disease gene therapy.

Ling S, Zhang X, Dai Y, Jiang Z, Zhou X, Lu S, Qian X, Liu J, Selfjord N, Satir TM, Lundin A, Touza JL, Firth M, Van Zuydam N, Bilican B, Akcakaya P, Hong J, Cai Y
Nature nanotechnology 2025 Apr;20(4):543-553

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WTAP Promotes Atherosclerosis by Inducing Macrophage Pyroptosis and M1 Polarization through Upregulating NLRP3.

Luo X, He C, Yang B, Yin S, Li K
Applied biochemistry and biotechnology 2025 Apr;197(4):2397-2416

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Elevated IGFBP7 expression in follicular granulosa cells promotes PCOS pathogenesis.

Chen L, Hui L, Wang Y, Yao X, Li J
Biochimica et biophysica acta. Molecular basis of disease 2025 Apr;1871(4):167743

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Glioblastoma- derived exosomes (GBM-Exo) regulate microglial M2 polarization via the RAC1/AKT/NRF2 pathway.

Wu Q, Chen S, Xie X, Yan H, Feng X, Su G, Zhang Z
Journal of neuro-oncology 2025 Apr;172(2):447-460

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Structurally diverse tetrahydroxanthone analogues from Paraconiothyrium sp. AC31 with pyroptosis induction through targeted inhibition of PARP1 in hepatocellular carcinoma cells.

Zhang MK, Hu QQ, He LM, Li M, Chen WC, Zhu KK, Yuan RY, Wu XY, Gao P, Zeng XB, Cai YS
Bioorganic chemistry 2025 Apr;157:108310

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Discovery of novel oleanolic acid glycoside derivatives targeting PTP1B/PI3K/AKT signaling pathway for the treatment of breast cancer.

Song X, Wang L, Liu Y, Xu K, Cai P, Liu J, Liu Q, Fan D
Bioorganic chemistry 2025 Apr;157:108296

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Synthesis and biological evaluation of novel isatin-phenol hybrids as potential antitumor agents.

Chen Z, Guo Y, Peng Y, Tan X, Chen H, Luo D, Luo K, Wu D, Huang Z, Yu Z, Tao C
Bioorganic chemistry 2025 Apr;157:108232

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Magnesium isoglycyrrhizinate prevented the liver injury of acetaminophen by promoting mitochondrial biogenesis.

Xia S, Hu ZY, Cao R, Guo L, Ma JT, Xiao MX, Liu J, Zhai BW, Fu R, Jiang ZC, Gong H, Yan M
Toxicology research 2025 Apr;14(2):tfaf024

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Smilax glabra roxb. alleviates cisplatin-induced acute kidney injury in mice by activating the Nrf2/HO-1 Signalling Pathway.

Zhao L, Yue Z, Wang G, Qin J, Ma H, Tang D, Yin G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156550

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Centipeda minima extract exhibits anti-liver cancer effects via the ER stress/HMOX1/Fe(2+)/ROS pathway.

Wei J, Zhao X, Wu B, Tan Z, Xie Y, Wei M, Wu L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156487

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Brusatol inhibits malignant phenotypes and lipid metabolism of osteosarcoma cells by regulating PI3K/AKT and MAPK pathways.

Yuan X, Yu S, Lin L, Chen Y, Wu Z, Fang X, Zhang W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156464

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6-C-methylquercetin in Baeckea frutescens exerts anti-prostate cancer effect via ErbB/PI3K/AKT pathway.

Jia B, Zhang M, Jiang X, Zhou S, Han K, Deng R, Cai H, Bi Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156463

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Palmatine activation of TFEB enhances autophagy and alleviates endoplasmic reticulum stress in intervertebral disc degeneration.

Yu H, Chen K, Li X, Liang J, Jin Y, Bao Y, Chen H, Gou Y, Lu K, Wu L, Lin Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156431

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Elevated serum levels of GPX4, NDUFS4, PRDX5, and TXNRD2 as predictive biomarkers for castration resistance in prostate cancer patients: an exploratory study.

Wang R, Wang S, Mi Y, Huang T, Wang J, Ni J, Wang J, Yin J, Li M, Ran X, Fan S, Sun Q, Tan SY, Phillip Koeffler H, Ding L, Chen YQ, Feng N
British journal of cancer 2025 Apr;132(6):543-557

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Positive Feedback Regulation between KLF5 and XPO1 Promotes Cell Cycle Progression of Basal like Breast Cancer.

Tang Y, Liu R, Zhu J, He Q, Pan C, Zhou Z, Sun J, Li F, Zhang L, Shi Y, Yao J, Jiang D, Chen C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(16):e2412096

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RFWD3 Reprograms Nucleotide Metabolism Through PHGDH to Induce Chemoresistance In Osteosarcoma.

Zhang W, Yin C, Qi L, Liu Z, Xu R, Tu C, Li Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(16):e2410937

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CpG-Based Nanovaccines Enhance Ovarian Cancer Immune Response by Gbp2-Mediated Remodeling of Tumor-Associated Macrophages.

Xiong J, Huang J, Xu H, Wu Q, Zhao J, Chen Y, Fan G, Guan H, Xiao R, He Z, Wu S, Ouyang W, Wang S, Zhang L, Xia P, Zhang W, Wu M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2412881

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HDAC2-Mediated METTL3 Delactylation Promotes DNA Damage Repair and Chemotherapy Resistance in Triple-Negative Breast Cancer.

He X, Li Y, Li J, Li Y, Chen S, Yan X, Xie Z, Du J, Chen G, Song J, Mei Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2413121

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Phosphorylation of POU3F3 Mediated Nuclear Translocation Promotes Proliferation in Non-Small Cell Lung Cancer through Accelerating ATP5PF Transcription and ATP Production.

Zeng QG, Li L, Chang T, Sun Y, Zheng B, Xue LN, Liu CL, Li XQ, Huang RT, Gu JX, An ZR, Yao HT, Zhou DY, Fan J, Dai Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(13):e2411503

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CYP24A1 Binding to FUS Maintains Tumor Properties by Regulating the miR-200c/ZEB1/EMT Axis.

Wang P, Xu J, You W, Li J, Yu J, Jiang F, Zhang Z, Hu W, Li B
Cancer science 2025 Apr;116(4):910-922

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Inhibition of MALAT1 facilitates ROS accumulation via the Keap1/HO-1 pathway to enhance photodynamic therapy in secondary hyperparathyroidism.

Wen Y, Li Y, Zhang D, Liu Z, Liu H, Li X, Wu W, Zeng L, Zou Q, Yi W
Non-coding RNA research 2025 Apr;11:249-261

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LncRNA NEAT1-206 regulates autophagy of human umbilical cord mesenchymal stem cells through the WNT5A/Ca(2+) signaling pathway under senescence stress.

Wang W, Wang Y, Duan C, Tian W, Gao L
Non-coding RNA research 2025 Apr;11:234-248

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Network Pharmacology Integrated Experimental Validation Uncover Quercetin as the Key Ingredient of Hedyotis diffusa Anti-BRCA.

Chen Q, Xu Y, Ma J, Zhang G, Yin Z, Zhang D, Luo D, Liu Z
Chemical biology & drug design 2025 Apr;105(4):e70112

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Nrf2 Deficiency Brings About Increased Sensitive to IR and 7,12-dimethylbenz(a)anthracene and Leukemia Predisposition.

Dong M, Yang P, Zhang X, Nie S, Sun X
Dose-response : a publication of International Hormesis Society 2025 Apr-Jun;23(2):15593258251341593

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Qilong capsule regulates microglial function and inhibits platelet activation after multiple cerebral infarctions by regulating the P2Y(12)/AC/cAMP signalling pathway.

Zhan M, Zheng X, Gao J, Shi S, Song W, Yao M, Sun L, Fan X, Zhang Y, Liu J
Journal of ethnopharmacology 2025 Apr 9;345:119586

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Using Cancer-Associated Fibroblasts as a Shear-Wave Elastography Imaging Biomarker to Predict Anti-PD-1 Efficacy of Triple-Negative Breast Cancer.

Zhang Z, Liang S, Zheng D, Wang S, Zhou J, Wang Z, Huang Y, Chang C, Wang Y, Guo Y, Zhou S
International journal of molecular sciences 2025 Apr 9;26(8)

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Electroacupuncture modulates the gut-brain axis via the PI3K/Akt pathway to improve feeding behavior, body weight, glucolipid metabolism, and reduce insulin resistance in T2DM rats.

Liu S, Zhuang S, Li R, Duan H
Diabetology & metabolic syndrome 2025 Apr 9;17(1):122

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MTCH2 regulates NRF2-mediated RRM1 expression to promote melanoma proliferation and dacarbazine insensitivity.

Zhang X, Li E, Kuang Y, Gai Y, Feng Y, Huang Y, Wei Z, Niu J, Yu S, Yang Z, Zhang Q, Sai B, Zhu Y
Cell death & disease 2025 Apr 9;16(1):268

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Targeting Viperin prevents coxsackievirus B3-induced acute heart failure.

Yuan Y, Qian L, Miao Y, Cui Q, Cao T, Yu Y, Zhang T, Zhao Q, Zhang R, Ren T, Zuo Y, Du Q, Qiao C, Wu Q, Zheng Z, Li M, Chinn YE, Xu W, Peng T, Chen R, Xiong S, Zheng H
Cell discovery 2025 Apr 8;11(1):34

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Sinomenine Inhibits TOPK To Ameliorate Psoriasiform Dermatitis.

Lu H, Zeng F, Gong H, Du J, Gao W, Xu J, Cai X, Yang Y, Xiao H
ACS omega 2025 Apr 8;10(13):13537-13547

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ACT001 improves OVX-induced osteoporosis by suppressing the NF-κB/NLRP3 signaling pathway.

Li Y, Yang JY, Lin ML, Liu TZ, Lu WN, Yang Y, Liu ZC, Li JH, Zhang GQ, Guo JS
Molecular medicine (Cambridge, Mass.) 2025 Apr 7;31(1):131

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LC-MS/MS assay to confirm that the endogenous metabolite L-Arginine promotes trophoblast invasion in the placenta accreta spectrum through upregulation of the GPRC6A/PI3K/AKT pathway.

Gao Z, Xue M, Wang Z
BMC pregnancy and childbirth 2025 Apr 7;25(1):402

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Febrile temperature-regulated TRPV1 in CD4(+) T cells mediates neuroinflammation in complex febrile seizures.

Kong S, Jia X, Liang X, Chen Y, Liang J, Zhang Y, Wu N, Su S, Chen T, He X, Yin J, Han S, Liu W, Fan Y, Xu J, Peng B
Journal of neuroinflammation 2025 Apr 7;22(1):103

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Berberine Suppresses Influenza A Virus-Triggered Pyroptosis in Macrophages via Intervening in the mtROS-MAVS-NLRP3 Inflammasome Pathway.

Zhao M, Deng D, Liu H, Guo R, Wu J, Hao Y, Yang M
Viruses 2025 Apr 7;17(4)

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Targeted Regulation of HSP70 by the ARP2/3 Complex in Mammary Epithelial Cells and Its Impact on Host Cell Apoptosis.

Yang T, Fang B, Chen Y, Bao D, Zhang J, Liu P, Duan Z, He Y, Zhao X, Zhang QW, Dong WT, Zhang Y
Biomolecules 2025 Apr 7;15(4)

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Lacc1-engineered extracellular vesicles reprogram mitochondrial metabolism to alleviate inflammation and cartilage degeneration in TMJ osteoarthritis.

Hu X, Xie J, Su J
Journal of nanobiotechnology 2025 Apr 5;23(1):276

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Chlorophyllin exerts synergistic anti-tumor effect with gemcitabine in pancreatic cancer by inducing cuproptosis.

Ren J, Su T, Ding J, Chen F, Mo J, Li J, Wang Z, Han L, Wu Z, Wu S
Molecular medicine (Cambridge, Mass.) 2025 Apr 4;31(1):126

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A small molecule directly targets NLRP3 to promote inflammasome activation and antitumor immunity.

Liu X, He H, Qi M, Jiang Z, Lin B, Wang X, Wang D, Ma M, Jiang W, Zhou R
Cell death & disease 2025 Apr 4;16(1):252

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Prdx5 regulates macrophage polarization by modulating the TLR4/NF-κB pathway to promote apoptosis in chronic prostatitis.

Wu W, Meng T, Wang Y, Chen J, Liang C
International immunopharmacology 2025 Apr 4;151:114332

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Astragaloside IV mitigates influenza-induced inflammatory responses by suppressing the Wnt/β-catenin signalling pathway in alveolar macrophages.

Tang J, Gao Y, Fu Y, Han Z, Xu P, Li X, Wang S, Wang X
Veterinary research 2025 Apr 30;56(1):95

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Gαq/11 Signaling Modulates Fibroblast Growth Factor 23 Production and Contributes to Acute Kidney Injury.

Jiang J, Zhang Y, Zuo Y, Bai Y, He Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 30;39(8):e70544

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Fullerol Initiates Stem Cell-Nanomaterials Interactions for Enhanced Tissue Regeneration via Clathrin-Mediated Endocytosis and Nuclear Factor Erythroid 2-Related Factor 2 Signaling.

Liu H, Zhu Y, Chen W, Sheng R, Liu C, Sun Y, Liu J, Wang M, Lu J, Chen J, Zhang W
ACS applied materials & interfaces 2025 Apr 30;17(17):25011-25034

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Early endolysosomal dysfunction is a contributing factor to gadolinium-based contrast agent mouse renal proximal tubule epithelial cell injury.

DeAguero J, Howard T, Escobar GP, Dokladny K, Wagner B
Cell biology and toxicology 2025 Apr 3;41(1):65

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Aldosterone-Induced Transformation of Vascular Smooth Muscle Cells into Macrophage-like Cells Participates in Inflammatory Vascular Lesions.

Zhang B, Liu Z, Chang Y, Lv R, Guo H, Qiang P, Shimosawa T, Xu Q, Yang F
International journal of molecular sciences 2025 Apr 3;26(7)

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Growth differentiation factor 15: a valuable biomarker for the diagnosis and prognosis of late-onset form of multiple Acyl-CoA dehydrogenation deficiency.

Yuan S, Shuyao T, Jingwei L, Bing W, Jingwen X, Busu L, Bing Z, Kunqian J, Chuanzhu Y
Orphanet journal of rare diseases 2025 Apr 3;20(1):159

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Repairing Qinling Giant Panda Skin Wounds Using Adipose Mesenchymal Stem Cell-Derived Extracellular Vesicles.

Gong S, Niu H, Jia Y, Liu M, Ren X, Zhang D, Shen J, Yang C, Lei Y, Zhao P, Lin P
Animals : an open access journal from MDPI 2025 Apr 29;15(9)

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The Six-Transmembrane Epithelial Antigen of the Prostate (STEAP) 3 Regulates the Myogenic Differentiation of Yunan Black Pig Muscle Satellite Cells (MuSCs) In Vitro via Iron Homeostasis and the PI3K/AKT Pathway.

Zhang W, Zhang M, Zhang J, Chen S, Zhang K, Xie X, Guo C, Shen J, Zhang X, Sun H, Guo L, Wen Y, Wang L, Hu J
Cells 2025 Apr 29;14(9)

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Intracellular and extracellular activities of V-domain Ig-containing suppressor of T cell activation (VISTA) modulated by immunosuppressive factors of tumour microenvironment.

Abooali M, Schlichtner S, Lei X, Aliu N, Ruggiero S, Loges S, Ziegler M, Hertel F, Volckmar AL, Stenzinger A, Christopoulos P, Thomas M, Klenova E, Meyer NH, Boussios S, Heaton N, Zen Y, Zamalloa A, Chokshi S, Urbani L, Richard S, Kirubendran K, Hussain R, Siligardi G, Cholewa D, Berger SM, Yasinska IM, Fasler-Kan E, Sumbayev VV
Cancer letters 2025 Apr 28;616:217581

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Possible Clinical Effects of Ketoconazole on Sorafenib-induced Hand-Foot Skin Reaction and Cytoprotection Mechanisms of Antifungal Agents against Multikinase Inhibitor-induced Keratinocyte Toxicity.

Kato R, Kamata Y, Tominaga M, Kishi R, Kaneko T, Tsujimura A, Suga Y, Takamori K
Acta dermato-venereologica 2025 Apr 28;105:adv40697

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N-deglycosylation targeting chimera (DGlyTAC): a strategy for immune checkpoint proteins inactivation by specifically removing N-glycan.

Li L, Wu J, Cao W, Zhang W, Wu Q, Li Y, Yang Y, Shan Z, Zheng Z, Ge X, Lin L, Wang P
Signal transduction and targeted therapy 2025 Apr 28;10(1):139

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Identification of potential hub genes associated with recurrent miscarriage through combined transcriptomic and proteomic analysis.

Xu HR, Yang L, Gu Y, Shi Y, Yang SH, Gan J, Gu WW, Zhang X, Wang J
Biomolecules & biomedicine 2025 Apr 26;25(6):1259-1279

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USP24 promotes hepatocellular carcinoma progression by deubiquitinating and stabilizing YAP1.

Shan H, Yuan J, Xian L, Li W, Ge Y, Zhang L, Lin T, Lan M, Liu J, Luo Y, Wu Y, Xiao X
Cancer cell international 2025 Apr 26;25(1):164

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Tanshinone IIA alleviates tri-ortho-cresyl phosphate-induced ovarian damage through Hippo signaling pathway activation in mice.

Ma Z, Hu N, Zheng L, Xue Y, Zhou C, Wang W, Cheng X, Luo T, Yu J, Hu L
Journal of ovarian research 2025 Apr 26;18(1):85

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Mapping the Interactome of KRAS and Its G12C/D/V Mutants by Integrating TurboID Proximity Labeling with Quantitative Proteomics.

Song J, Wang B, Zou M, Zhou H, Ding Y, Ren W, Fang L, Zhang J
Biology 2025 Apr 26;14(5)

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Comprehensive characterisation of bioactive compounds in Boletus edulis as functional foods to improve muscle atrophy; through whole plant targeted metabolomics, network pharmacology, in vivo and in vitro experiments, molecular docking and molecular dynamics analysis.

Zhang M, Chen M, Yan Y, Lu J, Sheng J, Gui M, Ma X
Journal of ethnopharmacology 2025 Apr 25;346:119685

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Sijunzi decoction improves lipid metabolism via regulation of Wnt/β-catenin signaling pathway in diabetic mice and 3T3-L1 cells.

Liu T, Liu Y, Shi H, Yue G, Dai X, Zhang Y, Wang S, Shen J, Xu T, Yin J, Zhang J, Zhang Y, Wang L, Zhou G, Zhang D
Journal of ethnopharmacology 2025 Apr 25;346:119672

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Epimedii Folium and Ligustri Lucidi Fructus synergistically delay renal aging through AMPK/ULK1/Bcl2L13-mediated mitophagy.

Long Y, Li Y, Ma Z, Xie Y, Zhao H, Zhang M, Liu R
Journal of ethnopharmacology 2025 Apr 25;346:119668

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Engineering aptamer-directed phosphatase recruiting chimeras: a strategy for modulating receptor function and overcoming drug resistance.

Zhou Z, Liu Y, Wang Y, Jiang H, Chen T, Zhu Y, Fu T, Li J
Nature communications 2025 Apr 25;16(1):3919

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Punicalagin relieves hepatic injury by antioxidation and enhancement of autophagy in diet-induced nonalcoholic steatohepatitis.

Ma L, Sun H, Xiang N, Xu Q
Scientific reports 2025 Apr 25;15(1):14516

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Restraint Stress Disrupted Intestinal Homeostasis via 5-HT/HTR7/Wnt/β-Catenin/NF-kB Signaling.

Yu J, Wang Z, Chen Y, Dong Y
International journal of molecular sciences 2025 Apr 24;26(9)

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Identification and Exploration of Pyroptosis-Related Genes in Macrophage Cells Reveal Necrotizing Enterocolitis Heterogeneity Through Single-Cell and Bulk-Sequencing.

Zhang P, Li Y, Xu P, Zou P, Sheng S, Xiao R, Xu P, Chen Y, Du Y, Ma L, Wang Y
International journal of molecular sciences 2025 Apr 24;26(9)

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OPA1 mutations in dominant optic atrophy: domain-specific defects in mitochondrial fusion and apoptotic regulation.

Zhang K, Zhang W, Zhang L, Hou X, Tian R, Hu Z, Yin L, Hu Z
Journal of translational medicine 2025 Apr 24;23(1):471

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Inhibition of ferroptosis alleviates atherosclerosis and foam cell formation by regulating lipid metabolism via AMPK activation.

Yang Y, Chen Z, Song D, Wu J, Wang J, YouyouYan
International immunopharmacology 2025 Apr 24;153:114553

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C1632 protects against LPS-induced acute lung injury by regulating AXL-mediated MAPK/NF-κB signaling pathway.

Mei Y, Wu Y, Zhai Y, Chen C, Han H, Wan L, Ma W, Ding M, Zheng X, Wu L
International immunopharmacology 2025 Apr 24;153:114542

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CRM1 mediates ASC nuclear export and inflammasome activation.

Cao R, Lin B, He H, Wang D, Wang X, Huang Y, Zhou R
International immunopharmacology 2025 Apr 24;153:114503

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Cold atmospheric plasma enhances immune clearance of Porphyromonas gingivalis via LC3-associated phagocytosis in mice with experimental periodontitis.

Yu W, Liu J, Yang C, Luo Y, Mu H, Wang S, Dong W, Jia M, Dong Z, Lu X, Wang J
International immunopharmacology 2025 Apr 24;153:114494

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N-acetylserotonin derivative ameliorates hypoxic-ischemic brain damage by promoting PINK1/Parkin-dependent mitophagy to inhibit NLRP3 inflammasome-induced pyroptosis.

Fang F, Tang J, Geng J, Fang C, Zhang B
International immunopharmacology 2025 Apr 24;153:114469

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Activation of GPR35 by kynurenic acid inhibits IL-1β secretion in macrophages during CR-hvKP-induced pneumonia.

Zhang Q, Meng B, Tang M, Li C, Xu Y, Pan J, Yu L, Li Y, Yang Y, Liu Y, Li H, Hu L, Wu T, Li J
International immunopharmacology 2025 Apr 24;153:114416

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Keto Acids Attenuate Skeletal Muscle Atrophy in Chronic Kidney Disease via Inhibiting Pyroptosis and Upregulating Irisin Precursor FNDC5 Expression.

Wang P, Pang Q, Zhang A
Calcified tissue international 2025 Apr 24;116(1):63

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THBS2-producing matrix CAFs promote colorectal cancer progression and link to poor prognosis via the CD47-MAPK axis.

Liu Z, Ba Y, Shan D, Zhou X, Zuo A, Zhang Y, Xu H, Liu S, Liu B, Zhao Y, Weng S, Wang R, Deng J, Luo P, Cheng Q, Hu X, Yang S, Wang F, Han X
Cell reports 2025 Apr 22;44(4):115555

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A neuronal Slit1-dependent program rescues oligodendrocyte differentiation and myelination under chronic hypoxic conditions.

Dai W, Nian X, Zhou Z, Du A, Liu Q, Jia S, Lu Y, Li D, Lu X, Zhu Y, Huang Q, Lu J, Xiao Y, Zheng L, Lei W, Sheng N, Zang X, Hou Y, Qiu Z, Xu R, Xu S, Zhang X, Zhang L
Cell reports 2025 Apr 22;44(4):115467

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GNF-5837 attenuates acute liver injury by inhibiting oxidative stress.

Zhou X, Luo X, Huang Q, Ru Y, Liu D, Linghu M, Huang Y
Molecular biology reports 2025 Apr 21;52(1):407

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Electroacupuncture Ameliorates Chronic Inflammatory Pain and Depression Comorbidity by Inhibiting Nrf2-Mediated Ferroptosis in Hippocampal Neurons.

Liu G, Liu D, Shi D, Wang Z, Fu W
Neurochemical research 2025 Apr 21;50(3):149

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FAM207A acts as a novel and potential biomarker in lung adenocarcinoma and shapes the immunesuppressive tumor microenvironment.

Wang L, Lin F, Yuan J, Wu X, Zhong Y, Li S, Lv Y
Clinical and experimental medicine 2025 Apr 21;25(1):125

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Neuronal ferroptosis in intracerebral hemorrhage shows gene regulation.

Chen K, Gu Y, Zhu X, Deng Q, Lei C
Gene 2025 Apr 20;946:149327

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MicroRNA-30a-3p Influences Milk Fat Metabolism by Targeting PTEN in Mammary Epithelial Cells of Sheep.

Guo Y, Wu X, Zhen H, Feng Y, Li M, Ren C, Wang J, Hao Z
Animals : an open access journal from MDPI 2025 Apr 20;15(8)

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PRDM16 suppresses pyroptosis to attenuate the progression of AKI caused by rhabdomyolysis via upregulation of USP10.

Han B, Zheng Q, Li H, Wang Y, Zhang D
Cellular and molecular life sciences : CMLS 2025 Apr 2;82(1):138

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Card9 deficiency exacerbates vulvovaginal candidiasis by impairing the IL-17 production and vaginal epithelial barrier.

Liu W, Song Y, Wang R, Wan Z, Li R, Wang X
Medical mycology 2025 Apr 2;63(4)

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Ticagrelor alleviates neuroinflammation after traumatic brain injury by inhibiting NLRP3 inflammasome-mediated pyroptosis.

Zhu S, Hu Z, Xu S, Tu Y
Neuroreport 2025 Apr 2;36(6):306-313

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HPV11E6/E7 induces nasal epithelial hyperplasia through JAK2/STAT3 signaling pathway.

Zhang Y, Tian K, Zheng L, Zhu G, Zhao R, Zhou E, Xue X, Huang S, Chen X, Hu B, Yao W
European journal of medical research 2025 Apr 2;30(1):224

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DCC-2036 inhibits osteosarcoma via targeting HCK and the PI3K/AKT-mTORC1 axis to promote autophagy.

He J, Yin L, Yuan Q, Su X, Shen Y, Deng Z
World journal of surgical oncology 2025 Apr 2;23(1):115

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Faecalibacterium prausnitzii-derived outer membrane vesicles reprogram gut microbiota metabolism to alleviate Porcine Epidemic Diarrhea Virus infection.

Xing J, Niu T, Yu T, Zou B, Shi C, Wang Y, Fan S, Li M, Bao M, Sun Y, Gao K, Qiu J, Zhang D, Wang N, Jiang Y, Huang H, Cao X, Zeng Y, Wang J, Zhang S, Hu J, Zhang D, Sun W, Yang G, Yang W, Wang C
Microbiome 2025 Apr 2;13(1):90

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Homocysteine Mediates Cognitive Inflexibility Induced by Stress via Targeting PIN1.

Chen X, Zhang L, Liu B, Dong H, Zhang S, Wang X, Sun Z, Xie F, Qian L, Zhao Y
Brain sciences 2025 Apr 19;15(4)

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NID2 Affects Prognosis of Glioma via Activating the Akt Signaling Pathway.

Lan Z, Xiao Y, Liao Y, Li X, Zhang Y, Wang H, Zhang W
International journal of molecular sciences 2025 Apr 18;26(8)

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Small-Molecule FICD Inhibitors Suppress Endogenous and Pathologic FICD-Mediated Protein AMPylation.

Chatterjee BK, Alam M, Chakravorty A, Lacy SM, Giblin W, Rech J, Brooks CL 3rd, Arvan P, Truttmann MC
ACS chemical biology 2025 Apr 18;20(4):880-895

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Ara-C suppresses H3 K27-altered spinal cord diffuse midline glioma growth and enhances immune checkpoint blockade sensitivity.

Pang B, Wu Y, An S, Chang Y, Yan H, Lin H, Zhao Z, Wu F, Chang Q, Jia W, Jiang T, Wang Y, Chai R
Science advances 2025 Apr 18;11(16):eadu3956

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TACC3 enhances glycolysis in bladder cancer cells through inducing acetylation of c-Myc.

Lin Z, Liang F, Hong G, Jiang X, Zhang Q, Wang M
Cell death & disease 2025 Apr 17;16(1):311

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IGF2BP3/ESM1/KLF10/BECN1 positive feedback loop: a novel therapeutic target in ovarian cancer via lipid metabolism reprogramming.

Gao A, Zou J, Zeng T, Qin M, Tang X, Yi T, Song G, Zhong J, Zeng Y, Zhou W, Gao Q, Zhang Q, Zhang J, Li Y
Cell death & disease 2025 Apr 17;16(1):308

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Combining RNA-seq, molecular docking and experimental verification to explore the mechanism of BAM15 as a potential drug for atherosclerosis.

Ma M, Zhong J, Tai Y, Xu S, Pei Z, Wang X
Scientific reports 2025 Apr 17;15(1):13347

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USP7 promotes endothelial activation to aggravate sepsis-induced acute lung injury through PDK1/AKT/NF-κB signaling pathway.

Liu Z, Shi X, Ke T, Yan Z, Xiong L, Tang F
Cell death discovery 2025 Apr 17;11(1):183

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Parabacteroides distasonis promotes CXCL9 secretion of tumor-associated macrophages and enhances CD8(+)T cell activity to trigger anti-tumor immunity against anti-PD-1 treatment in non-small cell lung cancer mice.

Fan Z, Yi Z, Li S, He J
BMC biotechnology 2025 Apr 16;25(1):30

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Ephrin B1 and B2 Mediate Cedar Virus Entry into Egyptian Fruit Bat Cells.

Lenhard L, Müller M, Diederich S, Loerzer L, Friedrichs V, Köllner B, Finke S, Dorhoi A, Pei G
Viruses 2025 Apr 16;17(4)

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Peptidomic profiling of mesenchymal stem cell-derived extracellular vesicles and anti-inflammatory activity of degraded peptides.

Chu T, Xiao Z, Xun C, Yang C, Lu M, Wang Y, Chen H, Chen P
International immunopharmacology 2025 Apr 16;152:114452

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PGRN knockdown alleviates pulmonary fibrosis regulating the Akt/GSK3β signaling pathway.

Xie T, Zheng Y, Zhang L, Zhao J, Wu H, Li Y
International immunopharmacology 2025 Apr 16;152:114443

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Jatrorrhizine retard obesity by modulating transcription factor c-Jun/c-Fos to downregulate Mmp12-mediated inflammation.

Ma Z, Li J, Zhu J, Yang Z, Li X, Wang H, Tang Q, Zhou Y, Manzoor R, Chen X, Ma H, Ye X
International immunopharmacology 2025 Apr 16;152:114405

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Aging and autophagic phenotypic changes in bone marrow mesenchymal stem cells in glucocorticoid-induced osteonecrosis.

Cao R, Li H, Liu G, Yan P, Zhang J, Chen Y, Duan X, Zhao Y, Lei Y, Liu C, Guan H, Xing F, Li Y, Wang K, Kong N, Tian R, Yang P
International immunopharmacology 2025 Apr 16;152:114389

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Puerarin alleviates silicon dioxide-induced pulmonary inflammation and fibrosis via improving Autophagolysosomal dysfunction in alveolar macrophages of murine mice.

Su W, Gong S, Luo Y, Ma X, Wei X, Song Y, Chen Q, Xu H, Ke C, He H, Shen F, Li J
International immunopharmacology 2025 Apr 16;152:114375

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Tumor vascular normalization by B7-H3 blockade augments T lymphocyte-mediated antitumor immunity.

Dai X, Cao B, Liu X, Meng W, Qiu Y, Sun Y, Zhang L, Li N, Liu Z, Li D, Xiao L, Li B, Zhang Q
European journal of pharmacology 2025 Apr 15;993:177334

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Porcine reproductive and respiratory syndrome virus nsp5 inhibits the activation of the Nrf2/HO-1 pathway by targeting p62 to antagonize its antiviral activity.

Wang F, Amona FM, Pang Y, Zhang Q, Liang Y, Chen X, Ke Y, Chen J, Song C, Wang Y, Li Z, Zhang C, Fang X, Chen X
Journal of virology 2025 Apr 15;99(4):e0158524

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The African swine fever virus MGF360-16R protein functions as a mitochondrial-dependent apoptosis inducer by competing with BAX to bind to the HSP60 protein.

Xiang Z, Xu Z, Weng W, Wang H, Wu J, Jiang F, Qu Y, Li Q, Gao P, Zhou L, Ge X, Guo X, Han J, Zhang Y, Yang H
Journal of virology 2025 Apr 15;99(4):e0140124

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Upregulation of ferroptosis in glucocorticoids-induced posterior subcapsular cataracts.

Zhang Y, Si W, Mao Y, Xu S, Li F, Liu J, Du S, Shao J, Qi Y, Peng X, Xue M, Jiang M, Guo K, Hu Y, Zhang F
Communications biology 2025 Apr 15;8(1):613

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Microneedle delivery of CAR-M-like engineered macrophages alleviates intervertebral disc degeneration through enhanced efferocytosis capacity.

Zhou X, Zhu D, Wu D, Li G, Liang H, Zhang W, Wu Y, Xu H, Zhang Z, Tong B, Song Y, Wang K, Feng X, Lei J, Wang H, Zhang X, Ma L, Chen Y, Wei J, Ou Z, Peng S, Wu X, Tan L, Wang B, Yang C
Cell reports. Medicine 2025 Apr 15;6(4):102079

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CircTHADA regulates endothelial cell pyroptosis in diabetic retinopathy through miR-494-3p/CASP1/GSDMD-N/IL-1β pathway.

He S, Gu C, Meng C, Cai C, Lai D, Qiu Q
Experimental cell research 2025 Apr 15;447(2):114496

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Artesunate induces ferroptosis in osteosarcoma through NCOA4-mediated ferritinophagy.

Huang R, Xu R, Shi J, Yang Z, Zheng J, Wei D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 15;39(7):e70488

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A novel feedback regulation loop of METTL11A-MAFG-NPL4 promotes bladder cancer cell proliferation and tumor progression.

Lu BS, Liu KL, Yin YW, Zhang YP, Qi JC, Zhao CM, Niu YL, Guo PY, Li W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 15;39(7):e70466

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Discovery of a novel Wnt inhibitor DK419: Reversing temozolomide resistance in glioblastoma by switching off Wnt/β-catenin signaling pathway to inhibit MGMT expression.

Bai P, Wang P, Ren T, Tang Q, Zhang N, Zhao L, Zhong R, Sun G
European journal of medicinal chemistry 2025 Apr 15;288:117411

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Discovery of β-amino acid substituted naphthalene sulfonamide derivatives as potent Kelch-like ECH-associated protein 1-nuclear factor erythroid 2-related factor 2 (Keap1-Nrf2) protein-protein interaction inhibitors for ulcerative colitis management.

Zhao Z, Lu H, Wang J, Wu T, Xu S, Ge Y, You Q, Jiang Z, Lu M
European journal of medicinal chemistry 2025 Apr 15;288:117384

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Discovery of novel sitolactone derivative leading to PANoptosis and differentiation of acute myeloid leukemia cells.

Wang J, Wang N, Wang M, Liu N, Wang C, Li N, Mu L, Jiang Y, Chen J, Li J, Yang G, Wang J, Liu S, Zhang K
European journal of medicinal chemistry 2025 Apr 15;288:117360

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Dl-3-n-butylphthalide ameliorates diabetic foot ulcer by inhibiting apoptosis and promoting angiogenesis.

Wei WH, Bai YL, Zhu D, Zhang JY, Yin QC, Li Q, Shen CQ, Jin PS
World journal of diabetes 2025 Apr 15;16(4):101916

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Rubidium ions as a novel therapeutic approach for glioblastoma.

Wang Z, Li Z, Yang R, Wang Y, Ma W, Lv X, Gao J, Li Y
Scientific reports 2025 Apr 15;15(1):12917

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Downregulation of the HCN1 Channel Alleviates Anxiety- and Depression-Like Behaviors in Mice With Cerebral Ischemia-Reperfusion Injury by Suppressing the NLRP3 Inflammasome.

Zhou M, Tao X, Lin K, Leng C, Yang Y, Gui Y, Sun Y, Zhou M, Sun B, Xia Y, Shu X, Liu W
Journal of the American Heart Association 2025 Apr 15;14(8):e038263

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PINK1-mediated mitophagy attenuates pathological cardiac hypertrophy by suppressing the mtDNA release-activated cGAS-STING pathway.

Zhou H, Wang X, Xu T, Gan D, Ma Z, Zhang H, Zhang J, Zeng Q, Xu D
Cardiovascular research 2025 Apr 15;121(1):128-142

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Acanthopanax Senticosus Saponins Prevent Cognitive Decline in Rats with Alzheimer's Disease.

Cui XM, Wang W, Yang L, Nie BW, Liu Q, Li XH, Duan DX
International journal of molecular sciences 2025 Apr 14;26(8)

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EXOSC5: a novel biomarker for poor prognosis in lung adenocarcinoma.

Xu J, Zhang Z, Han K, Yang Z, Guo F
BMC cancer 2025 Apr 14;25(1):681

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Inhibition of miR-325 inhibits KIF20B expression and the colorectal cancer cells' invasion & proliferation.

Zheng QQ, Lin WF
BMC cancer 2025 Apr 14;25(1):680

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Microvesicles carrying EV71 virions cross BBB through endocytic pathway to induce brain injury.

Tian X, Liu B, Li L, Yuan M, You Q, Zhang R, Chen D, Cheng M, Zheng N, He M, Wu Z
Cell communication and signaling : CCS 2025 Apr 14;23(1):183

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A novel peptide RR-171 derived from human umbilical cord serum induces apoptosis and pyroptosis in pancreatic cancer cells.

Chen W, Yang K, Liu X, Cheng X, Zhu D, Yang Z, Chen Y
Scientific reports 2025 Apr 14;15(1):12819

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Platelet-rich plasma relieves inflammation and pain by regulating M1/M2 macrophage polarization in knee osteoarthritis rats.

Xu J, Chen X, Zhang H, Zhang X, Liu R, Li X, Wang J, Li T
Scientific reports 2025 Apr 14;15(1):12805

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Dehydrocorydaline attenuates bleomycin-induced pulmonary fibrosis by inhibiting fibroblast activation.

He J, Yue H, Zhang S, Dong R, Zhang F, Wang X, Wang K, Zhang H, Yang D, Dong Z, Liu H
Respiratory research 2025 Apr 12;26(1):136

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Extracellular Vesicle-Liposome-Darunavir Formulation for the Treatment of HIV Neuropathogenesis.

Zhou L, Godse S, Sinha N, Ma D, Mirzahosseini G, Salman M, Pulliam P, Tan C, Singh UP, Ishrat T, Kochat H, Kumar S
ACS applied nano materials 2025 Apr 11;8(14):6857-6876

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Characterization of dsRNA binding proteins through solubility analysis identifies ZNF385A as a dsRNA homeostasis regulator.

Jiang N, Yang H, Lei Y, Qin W, Xiong H, Chen K, Mei K, Li G, Mu X, Chen R
Nature communications 2025 Apr 11;16(1):3433

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Effect of 1-DNJ on Oxidative Stress-Induced Apoptosis in Porcine Ovarian GCs Through Modulation of the PERK-ATF4/MFN2 Signaling Pathway.

Xing W, Li M, Wang B, Huo L, Tian W, Ge F, Shen M, Sun L, Liu J, Yu S
Antioxidants (Basel, Switzerland) 2025 Apr 11;14(4)

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NELL2, a novel osteoinductive factor, regulates osteoblast differentiation and bone homeostasis through fibronectin 1/integrin-mediated FAK/AKT signaling.

Yuan H, Wang X, Du S, Li M, Zhu E, Zhou J, Dong Y, Wang S, Shan L, Liu Q, Wang B
Bone research 2025 Apr 11;13(1):46

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Asparagine transporter supports macrophage inflammation via histone phosphorylation.

Wang C, Ye Y, Zhao M, Chen Q, Liu B, Ren W
Science advances 2025 Apr 11;11(15):eads3506

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High expression of SMPD4 promotes liver cancer and is associated with poor prognosis.

Wang R, Wang T, Su Y, Lin Z, Liu X, Jiao Y, Liu J, Chen E
BMC research notes 2025 Apr 10;18(1):159

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A TLK2-mediated calcium-driven cell death pathway links neuronal degeneration to nuclear envelope disruption.

Li Y, Huang H, Gao J, Lu J, Kang G, Ge Y, Jiang W, Cai X, Zhang G, Liu L
Nature communications 2025 Apr 10;16(1):3419

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Prox1 Protein in Corneal Limbal Lymphatic Vessels Maintains Limbal Stem Cell Stemness and Regulates Corneal Injury Repair.

Wang A, Li Z, Jiang Y, Chen M, Yu H, Li Z, Sun S, Bai G, Wang Q, Huang Y, Wang L
Investigative ophthalmology & visual science 2025 Apr 1;66(4):81

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Single-Cell RNA Sequencing Revealed Functional Conjunctival Keratinocytes Loss via TGF-β-Wnt/β-Catenin Signaling in Sjögren's Syndrome Related Dry Eye.

Wang B, Liang L, Zeng H, Yang X, Zhang R, Deng W, Wang X, Yuan J
Investigative ophthalmology & visual science 2025 Apr 1;66(4):43

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KGF-2 Alleviates Dry Eye Disease by Regulating the HMGB1/TLR4 Pathway.

Wang Y, Xu Z, Wei L, Lu Y, Shi Y, Wen S, Lv X, Huang K, Lu F, Qu J, Hu L
Investigative ophthalmology & visual science 2025 Apr 1;66(4):28

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Bisphenol A-induced cancer-associated adipocytes promotes breast carcinogenesis via CXCL12/AKT signaling.

Dong Z, He L, Wu J, Xie C, Geng S, Wu J, Zhong C, Li X
Molecular and cellular endocrinology 2025 Apr 1;599:112473

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Lack of ALCAT1 enhances the protective effects of aerobic exercise on kidney in HFpEF mice.

Zhang L, Feng L, Zhao Y, Geng Y, Liu R, Ma Y, Bo W, Xi Y, Tian Z
Life sciences 2025 Apr 1;366-367:123500

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Identification and validation of CDC20 and ITCH as ubiquitination related biomarker in idiopathic pulmonary fibrosis.

Sun S, Wang Y, Feng J
Hereditas 2025 Apr 1;162(1):50

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TMEM43 promotes the development of hepatocellular carcinoma by activating VDAC1 through USP7 deubiquitination.

Zhang N, Wang F, Yang X, Wang Q, Chang R, Zhu L, Feitelson MA, Chen Z
Translational gastroenterology and hepatology 2024;9:9

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REGγ deficiency ameliorates hepatic ischemia and reperfusion injury in a mitochondrial p66shc dependent manner in mice.

Guo L, Yang Q, Zhu J, Li J
Translational gastroenterology and hepatology 2024;9:62

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Oxidative stress mediates hippocampal neuronal apoptosis through ROS/JNK/P53 pathway in rats with PTSD triggered by high-voltage electrical burn.

Lv Y, Zhao X, Zhang R, He Z, Xu Y, Tu L, Jiang L, Xu S, Zhang Q
Folia morphologica 2024;83(2):300-313

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Radix Bupleuri-Radix Paeoniae Alba Inhibits the Development of Hepatocellular Carcinoma through Activation of the PTEN/PD-L1 Axis within the Immune Microenvironment.

Zhang F, Zhou K, Yuan W, Sun K
Nutrition and cancer 2024;76(1):63-79

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circRACGAP1 Promotes Proliferation of Non-Small Cell Lung Cancer Cells through the miR-1296/CDK2 Pathway.

Zhao Y, Deng L, Xie Y, Wang W, Chai Q, Wang G
Folia biologica 2024;70(2):104-112

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The role of TFEB-mediated autophagy-lysosome dysfunction in manganese neurotoxicity.

Lu J, Su P, Zhao F, Yu K, Yang X, Lv H, Wang D, Zhang J
Current research in toxicology 2024;7:100193

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Melatonergic Signaling Sustains Food Allergy Through FcεRI Recycling.

Wang Y, Zhang X, Hung I, Liu C, Ren W, Ge L, Wang H
Research (Washington, D.C.) 2024;7:0418

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Brain-Derived Neurotrophic Factor-TrkB Pathway on Synaptic Plasticity in Ischemic Stroke Rats.

Zhu X, Han S, Geng Y, Ren W, Quan F
International heart journal 2024;65(6):1095-1106

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Inhibition of IGF2BP1 attenuates the progression of endometriosis through PTBP1.

Su Y, Tian W, Cheng L, Yin L, He X, Wei X
Folia histochemica et cytobiologica 2024;62(1):25-36

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Schisandrin a Ameliorates Cardiac Injury and Dysfunction Induced by Hemorrhagic Shock via Activating the Nrf2 Signaling Pathway.

Li B, Zhou W, Zhang J, Wang N, Yang X, Ge X
The American journal of Chinese medicine 2024;52(8):2453-2468

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Astragaloside IV Ameliorates Colonic Adenomatous Polyps Development by Orchestrating Gut Bifidobacterium and Serum Metabolome.

Wen LP, Gao SW, Chen HX, Liu Q, Xiao GZ, Lin HC, He QL
The American journal of Chinese medicine 2024;52(5):1527-1554

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Hsa_circ_0008833 promotes COPD progression via inducing pyroptosis in bronchial epithelial cells.

Xie T, Yang Z, Xian S, Lin Q, Huang L, Ding Y
Experimental lung research 2024;50(1):1-14

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POMC Neuron BBSome Regulation of Body Weight is Independent of its Ciliary Function.

Guo DF, Williams PA, Laule C, Seaby C, Zhang Q, Sheffield VC, Rahmouni K
Function (Oxford, England) 2024;5(1):zqad070

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IRF9 and STAT1 as biomarkers involved in T-cell immunity in atherosclerosis.

Xie W, Gao X, Zhao L, Song S, Li NA, Liu J
Journal of biosciences 2024;49

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Chronic Corticosterone Treatment Decreases Extracellular pH and Increases Lactate Release via PDK4 Upregulation in Cultured Astrocytes.

Kita A, Araki R, Yabe T
Biological & pharmaceutical bulletin 2024;47(9):1542-1549

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ABCF1/CXCL12/CXCR4 Enhances Glioblastoma Cell Proliferation, Migration, and Invasion by Activating the PI3K/AKT Signal Pathway.

Yin X, Xia K, Peng S, Tan B, Huang Y, Wang M, He M
Developmental neuroscience 2024;46(3):210-220

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A Small Molecule Inhibitor of Leucine Carboxyl Methyltransferase-1 Inhibits Cancer Cell Survival.

Arosarena OA, Saribas AS, Papadopoulos EP
Frontiers in drug discovery 2024;4

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Isoflurane preconditioning protects against renal ischemia/reperfusion injury in diabetes via activation of the Brg1/Nrf2/HO-1 signaling pathway.

Gong D, Dong Z, Chen X, Chen H, Lin H
Acta cirurgica brasileira 2024;39:e396124

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Genetically Modified Hepatocytes Targeting Bilirubin and Ammonia Metabolism for the Construction of Bioartificial Liver System.

Wang K, Zhu Y, Li M, Yang Y, Zuo D, Sheng J, Zhang X, Wang W, Zhou P, Feng M
Biomaterials research 2024;28:0043

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Therapeutic potential of HUC-MSC-exos primed with IFN-γ against LPS-induced acute lung injury.

Wang C, Jiang C, Yang Y, Xi C, Yin Y, Wu H, Qian C
Iranian journal of basic medical sciences 2024;27(3):375-382

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Catalpol alleviates amyloid- generation and neuronal oxidative stress injury via activating the Keap1-Nrf2/ARE signaling pathway in the immortalized lymphocytes from patients with late-onset Alzheimer's disease and SKNMC cells co-culture model.

Xiang C, Lu Y, Hao R, Wei Y, Hu Y, Yu G
Iranian journal of basic medical sciences 2024;27(12):1547-1557

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PR/SET domain 1 targeting glutathione peroxidase 4 regulates chronic hepatitis B liver fibrosis through ferroptosis.

Wu W, Ke W, Shi W, Lin T, Lin S, Lin M, Ma H, Gao H
CytoJournal 2024;21:78

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Potential Association of Gut Microbial Metabolism and Circulating mRNA Based on Multiomics Sequencing Analysis in Fetal Growth Restriction.

Tang H, Li D, Peng J, Yang W, Zhang X, Li H
Mediators of inflammation 2024;2024:9986187

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Infectivity and Potential Zoonotic Characteristics of Porcine Pseudorabies Virus in Human Cells.

Li X, Li N, Zheng J, Lv X, Han Y, Zhang H, Ren Y, Yin G, Ren L
Transboundary and emerging diseases 2024;2024:5929976

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Combination of Pirfenidone and Andrographolide Ameliorates Hepatic Stellate Cell Activation and Liver Fibrosis by Mediating TGF-β/Smad Signaling Pathway.

Xu G, Ma T, Zhou C, Zhao F, Peng K, Li B
Analytical cellular pathology (Amsterdam) 2024;2024:2751280

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Peptide BG From Bitter Gourd (Momordica Charantia) Improves Adjuvant-Induced Arthritis by Modulating the Necroptosis/Neutrophil Extracellular Traps/Inflammation Axis and the Gut Microbiota.

Han W, Xu Y, Qimuge S, Wang C, Su X
Mediators of inflammation 2024;2024:1995952

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Aberrant Expression of SLC7A11 Impairs the Antimicrobial Activities of Macrophages in Staphylococcus Aureus Osteomyelitis in Mice.

Yang B, Shu W, Hu J, Wang Z, Wu J, Su J, Tan J, Yu B, Zhang X
International journal of biological sciences 2024;20(7):2555-2575

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NUP85 alleviates lipid metabolism and inflammation by regulating PI3K/AKT signaling pathway in nonalcoholic fatty liver disease.

Wu YC, Yan Q, Yue SQ, Pan LX, Yang DS, Tao LS, Wei ZY, Rong F, Qian C, Han MQ, Zuo FC, Yang JF, Xu JJ, Shi ZR, Du J, Chen ZL, Xu T
International journal of biological sciences 2024;20(6):2219-2235

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Apigenin targets fetuin-A to ameliorate obesity-induced insulin resistance.

Hsu MC, Chen CH, Wang MC, Chen WH, Hu PA, Guo BC, Chang RW, Wang CH, Lee TS
International journal of biological sciences 2024;20(5):1563-1577

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Dissection of Targeting Molecular Mechanisms of Celastrol-induced Nephrotoxicity via A Combined Deconvolution Strategy of Chemoproteomics and Metabolomics.

Liu X, Zhang Q, Wang P, Peng X, An Y, Chen J, Huang J, Qin S, He H, Hao M, Tian J, Yi L, Lei M, Luo P, Wang J, Zhang X
International journal of biological sciences 2024;20(12):4601-4617

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Exosomal SLC16A1-AS1-induced M2 macrophages polarization facilitates hepatocellular carcinoma progression.

Hu Y, Li Y, Xiong H, Zhang Y, Wang F, Zhuo W, Zeng Z, Zhao Y, Wang H, Hu P, Han S, Huang Y, Lv G, Zhao G
International journal of biological sciences 2024;20(11):4341-4363

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Single-cell and Spatial Transcriptomics Reveals Ferroptosis as The Most Enriched Programmed Cell Death Process in Hemorrhage Stroke-induced Oligodendrocyte-mediated White Matter Injury.

Gu L, Chen H, Geng R, Sun M, Shi Q, Chen Y, Chang J, Wei J, Ma W, Xiao J, Bao X, Wang R
International journal of biological sciences 2024;20(10):3842-3862

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HNF4A-Bridging the Gap Between Intestinal Metaplasia and Gastric Cancer.

Zhao Y, Tang H, Xu J, Sun F, Zhao Y, Li Y
Evolutionary bioinformatics online 2024;20:11769343241249017

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Maggot extract accelerates skin wound healing of diabetic rats via enhancing STAT3 signaling.

Wu ML, Yang ZM, Dong HC, Zhang H, Zheng X, Yuan B, Yang Y, Liu J, Li PN
PloS one 2024;19(9):e0309903

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Benfotiamine protects MPTP-induced Parkinson's disease mouse model via activating Nrf2 signaling pathway.

Wang K, Han C, Yang J, Xu W, Wang L, Li H, Wang Y
PloS one 2024;19(7):e0307012

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Preclinical studies of RA475, a guanidine-substituted spirocyclic candidate RPN13/ADRM1 inhibitor for treatment of ovarian cancer.

Anchoori RK, Tseng SH, Tsai HL, Palande V, Rudek MA, Roden RBS
PloS one 2024;19(7):e0305710

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Proteomics analysis of deep fascia in acute compartment syndrome.

Wang H, Liu Y, Xu S, Wang T, Chen X, Jia H, Dong Q, Zhang H, Wang S, Ma H, Hou Z
PloS one 2024;19(7):e0305275

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hnRNP Q/SYNCRIP interacts with LIN28B and modulates the LIN28B/let-7 axis in human hepatoma cells.

Chang JJ, Lin T, Jhang XY, Chan SP
PloS one 2024;19(7):e0304947

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Trilobatin ameliorates dextran sulfate sodium-induced ulcerative colitis in mice via the NF-κB pathway and alterations in gut microbiota.

Wang N, Li Z, Cao L, Cui Z
PloS one 2024;19(6):e0305926

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Echinatin attenuates acute lung injury and inflammatory responses via TAK1-MAPK/NF-κB and Keap1-Nrf2-HO-1 signaling pathways in macrophages.

Luo L, Wang H, Xiong J, Chen X, Shen X, Zhang H
PloS one 2024;19(5):e0303556

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Comprehensive analysis and validation reveal DEPDC1 as a potential diagnostic biomarker associated with tumor immunity in non-small-cell lung cancer.

Lv M, Li X, Yin Z, Yang H, Zhou B
PloS one 2024;19(4):e0294227

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A comparative study of apoptosis, pyroptosis, necroptosis, and PANoptosis components in mouse and human cells.

Choudhury SM, Sarkar R, Karki R, Kanneganti TD
PloS one 2024;19(2):e0299577

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Exploring the effects of hypoxia and reoxygenation time on hepatocyte apoptosis and inflammation.

Xu X, Zhou T, Tulahong A, Ruze R, Shao Y
PloS one 2024;19(11):e0310535

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Establishment of a tumor-associated fibroblast associated gene score based on scRNA-seq to predict prognosis in patients with triple-negative breast cancer.

Yu H, Peng Z, Li X, Zhang Y
PloS one 2024;19(10):e0311801

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The deubiquitinating enzyme USP35 regulates the stability of NRF2 protein.

Zhang D, Li J, Zhang C, Xue J, Li P, Shang K, Zhang X, Lang B
Open life sciences 2024;19(1):20220935

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Molybdenum Nanoparticles Alleviate MC903-Induced Atopic Dermatitis-Like Symptoms in Mice by Modulating the ROS-Mediated NF-κB and Nrf2 /HO-1 Signaling Pathways.

Xiao Q, Guo J, Lu Y, Gao J, Jia C, Huang M, Chu W, Yao W, Ning P, Xu Q, Xu N
International journal of nanomedicine 2024;19:8779-8796

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Liposomes Loaded with 5-Fluorouracil Can Improve the Efficacy in Pathological Scars.

Li Y, Sun Q, Hao L, Shan H, Jiang Z, Wang Y, Chen Z, Zhu W, Zhao S
International journal of nanomedicine 2024;19:7353-7365

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Polydopamine-Based Nanoparticles for Synergistic Chemotherapy of Prostate Cancer.

Hu K, Zhang D, Ma W, Gu Y, Zhao J, Mu X
International journal of nanomedicine 2024;19:6717-6730

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Administration of Liposomal-Based Pde3b Gene Therapy Protects Mice Against Collagen-Induced Rheumatoid Arthritis via Modulating Macrophage Polarization.

Chen L, Zhou Q, Fang X, Xu Q, Zou Y, Zhang J
International journal of nanomedicine 2024;19:4411-4427

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Unexpected Inhibitory Role of Silica Nanoparticles on Lung Cancer Development by Promoting M1 Polarization of Macrophages.

Xiang M, Chen C, Chen Y, Zhang Y, Shi L, Chen Y, Li J, Li B, Zeng B, Xing HR, Wang J, Zou Z
International journal of nanomedicine 2024;19:11087-11104

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Mesencephalic Astrocyte-derived Neurotrophic Factor Supports Hepatitis B Virus-induced Immunotolerance.

Xie H, Deng H, Yang X, Gao X, Yang S, Chen W, Wang Y, Yang N, Yong L, Hou X
Cellular and molecular gastroenterology and hepatology 2024;18(3):101360

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Rebaudioside B Attenuates Lung Ischemia-reperfusion Injury Associated Apoptosis and Inflammation.

Wu X, Qiao T, Huang J, Li J, Wei S, Yang J, Zhang Y, Li Y
Recent advances in inflammation & allergy drug discovery 2024;18(2):156-166

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Baolier Capsule's Secret Weapon: Piperine Boosts Cholesterol Excretion to Combat Atherosclerosis.

Wei M, LYu P, Li P, Hu J, Wu R, Ouyang Q, Guo K
Drug design, development and therapy 2024;18:6427-6446

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Modified Zuo Gui Wan Ameliorates Ovariectomy-Induced Osteoporosis in Rats by Regulating the SCFA-GPR41-p38MAPK Signaling Pathway.

Song C, Yan Q, Ma Y, Li P, Yang Y, Wang Y, Li W, Wan X, Li Y, Zhu R, Liu H, Zhang Z
Drug design, development and therapy 2024;18:6359-6377

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CXCR2 Activated JAK3/STAT3 Signaling Pathway Exacerbating Hepatotoxicity Associated with Tacrolimus.

Chen X, Hu K, Zhang Y, He SM, Wang DD
Drug design, development and therapy 2024;18:6331-6344

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The Therapeutic Potential of Pristimerin in Osteoarthritis: Mechanistic Insights from in vitro and in vivo Studies.

Yin L, Fan Y, Zhong X, Meng X, He Z, Hong Z, Chen J, Zhang Q, Kong M, Wang J, Tong Y, Bi Q
Drug design, development and therapy 2024;18:5445-5459

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Combining Network Pharmacology and Transcriptomics to Investigate the Mechanisms of Yujiang Paidu Decoction in the Treatment of Chronic Rhinosinusitis with Nasal Polyps.

Li Y, Yin Y, Xiong J, Zhang Z, Li L, Zhang B, Zhang F, Mao D
Drug design, development and therapy 2024;18:3791-3809

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Therapeutic Effects of Qingchang Tongluo Decoction on Intestinal Fibrosis in Crohn's Disease: Network Pharmacology, Molecular Docking and Experiment Validation.

Li Y, Hu J, Au R, Cheng C, Xu F, Li W, Wu Y, Cui Y, Zhu L, Shen H
Drug design, development and therapy 2024;18:3269-3293

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Xinfeng Capsule Inhibits Pyroptosis and Ameliorates Myocardial Injury in Rats with Adjuvant Arthritis via the GAS5/miR-21/TLR4 Axis.

Fu W, Cao Y, Liu J, Huang C, Shu K, Zhu N
Drug design, development and therapy 2024;18:2421-2433

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Perioperative enriched environment attenuates postoperative cognitive dysfunction by upregulating microglia TREM2 via PI3K/Akt pathway in mouse model of ischemic stroke.

Yao Y, Hu L, Li D, Wang Y, Pan J, Fan D
Frontiers in neuroscience 2024;18:1520710

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SARS-CoV-2 Nsp7 plays a role in cognitive dysfunction by impairing synaptic plasticity.

Guo J, Li W, Huang M, Qiao J, Wan P, Yao Y, Ye L, Ding Y, Wang J, Peng Q, Liu W, Xia Y, Shu X, Sun B
Frontiers in neuroscience 2024;18:1490099

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Propofol and Dexmedetomidine Ameliorate Endotoxemia-Associated Encephalopathy via Inhibiting Ferroptosis.

Zhou Y, Yang Y, Yi L, Pan M, Tang W, Duan H
Drug design, development and therapy 2024;18:1349-1368

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DNMT3B Alleviates Liver Steatosis Induced by Chronic Low-grade LPS via Inhibiting CIDEA Expression.

Li Q, Wang W, Duan F, Wang Y, Chen S, Shi K, Xia Y, Li X, Gao Y, Liu G
Cellular and molecular gastroenterology and hepatology 2024;17(1):59-77

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Deferoxamine Treatment Effectively Prevents Periodontitis Progression by Reducing Inflammation and Osteoclastogenesis in Experimental Periodontitis Rats.

Zhu Y, Qiao S, Pang Y, Wang H, Zhou Y
Journal of inflammation research 2024;17:9637-9650

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Fusobacterium Nucleatum Aggravates Intestinal Barrier Impairment and Colitis Through IL-8 Induced Neutrophil Chemotaxis by Activating Epithelial Cells.

Wang Z, Li B, Bao L, Chen Y, Yang J, Xu F, Shi S, Chen W, Wang B, Liu Y
Journal of inflammation research 2024;17:8407-8420

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Study on the Anti-Atherosclerotic Mechanisms of Xin-Tong-Tai Granule Through Network Pharmacology, Molecular Docking, and Experimental Validation.

Zhu J, Wang Z, Liu C, Shi M, Guo Z, Li Y, Yu R, Wei J
Journal of inflammation research 2024;17:8147-8164

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Synergistic Effect of Ubiquitin-Specific Protease 14 and Poly(ADP-Ribose) Glycohydrolase Co-Inhibition in BRCA1-Mutant, Poly(ADP-Ribose) Polymerase Inhibitor-Resistant Triple-Negative Breast Cancer Cells.

Li P, Zhu X, Qu H, Han Z, Yao X, Wei Y, Li B, Chen H
OncoTargets and therapy 2024;17:741-753

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Shenfu Injection Mediated NLRP3/Caspase 1 Through (R)-Norcoclaurinee Alleviates Sepsis-Induced Cognitive Dysfunction.

Liu X, Ding H, Chen M, Li X, Xiao Y, Han Y, Zeng H
Journal of inflammation research 2024;17:7295-7310

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The AGEs/RAGE Signaling Pathway Regulates NLRP3-Mediated Neuronal Pyroptosis After MCAO Injury in Lepr(-/-) Obese Rats.

Zhao L, Li S, Wang X, Zhang L, Zhang J, Liu X, Hu Y, Xian X, Zhang F, Li W, Zhang M
Journal of inflammation research 2024;17:6935-6954

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Nrf2 Deficiency Exacerbates Parkinson's Disease by Aggravating NLRP3 Inflammasome Activation in MPTP-Induced Mouse Models and LPS-Induced BV2 Cells.

Lu R, Zhou X, Zhang L, Hao M, Yang X
Journal of inflammation research 2024;17:6277-6295

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NLRP3 Inflammasome Inhibition After Pilocarpine-Induced Status Epilepticus Attenuates Chronic Inflammation in Epileptic Mice.

Wang L, Wang K, Chen Y, Zhang X, Xu W, Dong Z, Wang Y
Journal of inflammation research 2024;17:6143-6158

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Downregulation of ST6GAL2 Correlates to Liver Inflammation and Predicts Adverse Prognosis in Hepatocellular Carcinoma.

Liu R, Yu X, Cao X, Wang X, Liang Y, Qi W, Ye Y, Zao X
Journal of inflammation research 2024;17:565-580

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Sertraline Alleviates Chronic Prostatitis by Regulating the TRPV1 Channel.

Lao Y, Bai Y, Guan X, Wang J, Wang Y, Li R, Ding Y, Dong Z
Journal of inflammation research 2024;17:4257-4275

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Tat-CIRP Peptide Facilitates Frozen Wound Healing by Ameliorating Inflammation and Promoting Angiogenesis.

Li J, Ding J, Wu H, Lu C, Wu J, Luo Q
Journal of inflammation research 2024;17:2205-2215

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Inhibitory Effect of Evodiamine on Psoriasis Lesions and Itching in Mice.

Liang J, Chen W, Zhou Y, Meng W, Xie M, Weng Y, Qin L, Li J, Wu G
Clinical, cosmetic and investigational dermatology 2024;17:1527-1541

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Effect of histone demethylase KDM5B on long-term cognitive impairment in neonatal rats induced by sevoflurane.

Wang Y, Chen Y, Zhang M, Yuan C, Zhang Y, Liu X, Zhang Y, Liang X
Frontiers in molecular neuroscience 2024;17:1459358

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Maresin-1 Attenuates Sepsis-Associated Acute Kidney Injury via Suppressing Inflammation, Endoplasmic Reticulum Stress and Pyroptosis by Activating the AMPK/SIRT3 Pathway.

Sun M, Wang F, Li H, Li M, Wang Y, Wang C, Zhang Y, Zhang D, Li J, Yao S
Journal of inflammation research 2024;17:1349-1364

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SIRT2 Promotes NLRP3-Mediated Microglia Pyroptosis and Neuroinflammation via FOXO3a Pathway After Subarachnoid Hemorrhage.

Sun JQ, Sheng B, Gao S, Liu XZ, Cui Y, Peng Z, Chen XX, Ding PF, Zhuang Z, Wu LY, Hang CH, Li W
Journal of inflammation research 2024;17:11679-11698

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Candida albicans-Derived β-Glucan as a Novel Modulator of Tumor Microenvironment: Targeting Macrophage Polarization and Inducing Ferroptosis in Lung Cancer.

He X, Ran Q, Li X, Xiong A, Zhang L, Jiang M, Bai L, Peng D, Wang J, Sun B, Li G
Journal of inflammation research 2024;17:10479-10494

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MAT2A inhibition suppresses inflammation in Porphyromonas gingivalis-infected human gingival fibroblasts.

Jiang L, Li J, Ji K, Lei L, Li H
Journal of oral microbiology 2024;16(1):2292375

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MiR-15b-3p weakens bicalutamide sensitivity in prostate cancer via targeting KLF2 to suppress ferroptosis.

Zhang C, Yu H, Bai X, Zhou X, Feng Z, Li Y, Peng X, Mei Y, Li L, Gou X, Deng Y, Chen G
Journal of Cancer 2024;15(8):2306-2317

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Cuproptosis-related genes score and its hub gene GCSH: A novel predictor for cholangiocarcinomas prognosis based on RNA seq and experimental analyses.

He R, Li Y, Jiao P, Huang Y, Dong S, Mo L, Jiao X
Journal of Cancer 2024;15(6):1551-1567

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AQP3 Promotes the Invasion and Metastasis in Cervical Cancer by Regulating NOX4-derived H(2)O(2) Activation of Syk/PI3K/Akt Signaling Axis.

Wang Q, Lin B, Wei H, Wang X, Nie X, Shi Y
Journal of Cancer 2024;15(4):1124-1137

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CENPW knockdown inhibits progression of bladder cancer through inducing cell cycle arrest and apoptosis.

Zhang P, Yang Q, Chen X, Chen X, Wang Q, Chen K, An Y, Jiang K, Sun F
Journal of Cancer 2024;15(3):858-870

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Exploring the biological behavior and underlying mechanism of KITLG in triple-negative breast cancer.

Qin L, Li Y, Huang Y, Tang C, Yang W, Tang Y, Qiu C, Mao M, Li J
Journal of Cancer 2024;15(3):764-775

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Radiosensitization of Osteosarcoma Cells Using the PARP Inhibitor Olaparib Combined with X-rays or Carbon Ions.

Dong M, Luo H, Liu R, Zhang J, Yang Z, Wang D, Wang Y, Chen J, Ou Y, Zhang Q, Wang X
Journal of Cancer 2024;15(3):699-713

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Expression and clinical significance of ECHS1 in gastric cancer.

Lu T, Sun L, Fan Q, Yan J, Zhao D, Xu C, Dong F
Journal of Cancer 2024;15(2):418-427

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MLPH regulates EMT in pancreatic adenocarcinoma through the PI3K-AKT signaling pathway.

Wei M, Yang X, Yang X, Huang Y, Yuan Z, Huang J, Wei J, Tian L
Journal of Cancer 2024;15(17):5828-5838

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Apolipoprotein L3 inhibits breast cancer proliferation and modulates cell cycle via the P53 pathway.

Yu H, Li S, Li X, Liu Y, Wang Z, Cui M, Jin F, Yu X
Journal of Cancer 2024;15(14):4623-4635

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Hypoxia-responsive gene F3 Promotes GBM Cell Proliferation and Migration through Activating NF-κB/p65 Signaling Pathway.

Yu A, Wang Y, Qin J, Lei J, Bao W, Dong Z
Journal of Cancer 2024;15(14):4477-4489

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Investigating the mechanism and the effect of aquaporin 5 (AQP5) on the self-renewal capacity of gastric cancer stem cells.

Gao P, Chen A, Tian H, Wang F, Wang N, Ge K, Lian C, Wang F, Zhang Q
Journal of Cancer 2024;15(13):4313-4327

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Branched-Chain Amino Acid Degradation Pathway was Inactivated in Colorectal Cancer: Results from a Proteomics Study.

Lian S, Liu S, Wu A, Yin L, Li L, Zeng L, Zhao M, Zhang L
Journal of Cancer 2024;15(12):3724-3737

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PSAT1 mediated EMT of colorectal cancer cells by regulating Pl3K/AKT signaling pathway.

Wang M, Zhang H, Lu Z, Su W, Tan Y, Wang J, Jia X
Journal of Cancer 2024;15(10):3183-3198

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Qizhu Rougan Granules suppress liver fibrosis by inhibiting the expression of the P2Y14 receptor on hepatic stellate cells.

Tao Y, Niu Q, Yao Y, Wang K, Dong H, Zhao X, Zeng Z, Li H
Frontiers in pharmacology 2024;15:1528100

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Gualou Guizhi Granule inhibits microglia-mediated neuroinflammation to protect against neuronal apoptosis in vitro and in vivo.

Li X, Huang H, Li Y, Feng Y, Wang J, Luo S, Chen Y, Zhang Y, Yan G, Nan L
Frontiers in immunology 2024;15:1527986

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Gut microbiota derived metabolite trimethylamine N-oxide influences prostate cancer progression via the p38/HMOX1 pathway.

Zhou Y, Lv J, Jin S, Fu C, Liu B, Shen Y, Li M, Zhang Y, Feng N
Frontiers in pharmacology 2024;15:1526051

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NUP155 and NDC1 interaction in NSCLC: a promising target for tumor progression.

Li KM, Meng LF, Yang ZH, Hu WT
Frontiers in pharmacology 2024;15:1514367

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FGF21 ameliorates diabetic nephropathy through CDK1-dependently regulating the cell cycle.

Zhang Y, Wang F, Zhang C, Yao F, Zhang B, Zhang Y, Sun X
Frontiers in pharmacology 2024;15:1500458

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ABCA1 promote tumor environment heterogeneity via epithelial mesenchymal transition in Huh7 and HepG2 liver cancer cell.

Yu D, Guo F, Zhang Q, Yu H, Wang W, Chen Y
Frontiers in pharmacology 2024;15:1498528

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Clopidogrel ameliorates high-fat diet-induced hepatic steatosis in mice through activation of the AMPK signaling pathway and beyond.

Tai T, Shao YY, Zheng YQ, Jiang LP, Han HR, Yin N, Li HD, Ji JZ, Mi QY, Yang L, Feng L, Duan FY, Xie HG
Frontiers in pharmacology 2024;15:1496639

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Polyketides and alkaloids from the fungus Aspergillus Fumigatus YB4-17 and ent-Fumiquinazoline J induce apoptosis, paraptosis in human hepatoma HepG2 cells.

Wang H, Sun L, Ma X, Jin S, Xi Y, Sai C, Yan M, Cheng Z, Zhang Z
Frontiers in pharmacology 2024;15:1487977

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Insulin like growth factor 2 mRNA binding protein 2 regulates vascular development in cerebral arteriovenous malformations.

Wang LJ, Wu Y, Xie S, Lian H
Frontiers in neurology 2024;15:1483016

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β-cryptoxanthin suppresses oxidative stress via activation of the Nrf2/HO-1 signaling pathway in diabetic kidney disease.

Ke J, Zang H, Liu Y, Teng Q, Hua J, Peng D, Wang P
Frontiers in pharmacology 2024;15:1480629

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The role of SIRT1-FXR signaling pathway in valproic acid induced liver injury: a quantitative targeted metabolomic evaluation in epileptic children.

Zhao M, Li G, Zhao L
Frontiers in pharmacology 2024;15:1477619

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Calcium sensing receptor regulate claudin-14 via PKA-STAT3 pathway in rat model of nephrolithiasis.

Luo P, Chen T, Zheng L, Zou J, Zou J, Li W, Chen Q, Cheng L, Qian B
Frontiers in pharmacology 2024;15:1477122

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GRB7-mediated enhancement of cell malignant characteristics induced by Helicobacter pylori infection.

Zhao H, Chen S, Bai X, Zhang J, Liu S, Sun Z, Cao X, Wang J, Zhang Y, Li B, Ji X
Frontiers in microbiology 2024;15:1469953

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Thymic stromal lymphopoietin modulates T cell response and improves cardiac repair post-myocardial infarction.

Wang X, Zheng Q, Zha L, Zhang L, Huang M, Zhang S, Zhang X, Li Q, Chen X, Xia N, Zhang M, Lv B, Jiao J, Lu Y, Gu M, Yang F, Li J, Li N, Cheng X, Zhou Z, Tang T
Frontiers in immunology 2024;15:1467095

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Oncoproteins E6 and E7 upregulate topoisomerase I to activate the cGAS-PD-L1 pathway in cervical cancer development.

Luo Y, Niu M, Liu Y, Zhang M, Deng Y, Mu D, Xu J, Hong S
Frontiers in pharmacology 2024;15:1450875

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Qingre Huoxue decoction attenuates myocardial ischemia‒reperfusion injury by regulating the autophagy‒endoplasmic reticulum stress axis via FAM134B-mediated ER-phagy.

Li R, Zhang J, Ji S, Fang J, Ji X, Zeng Y, Liu N, Wu W, Liu S
Frontiers in pharmacology 2024;15:1447610

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Effects of Weizhuan'an on rats with precancerous lesions of gastric cancer based on regulating gastric mucosal microflora and inflammatory factors.

Lu Y, Liu H, Shang J, Mao Y, Meng L, Gao C
Frontiers in pharmacology 2024;15:1446244

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RAB42 overexpression correlates with poor prognosis, immune cell infiltration and chemoresistance.

Wang Y, Xie Y, Qian L, Ding R, Pang R, Chen P, Zhang Q, Zhang S
Frontiers in pharmacology 2024;15:1445170

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Hemoglobin α-derived peptides VD-hemopressin (α) and RVD-hemopressin (α) are involved in electroacupuncture inhibition of chronic pain.

Yuan X, Guo Y, Yi H, Hou X, Zhao Y, Wang Y, Jia H, Baba SS, Li M, Huo F
Frontiers in pharmacology 2024;15:1439448

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Identification of biomarkers and potential drug targets in osteoarthritis based on bioinformatics analysis and mendelian randomization.

Cheng F, Li M, Hua H, Zhang R, Zhu Y, Zhu Y, Zhang Y, Tong P
Frontiers in pharmacology 2024;15:1439289

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Licoricesaponin G2 ameliorates bleomycin-induced pulmonary fibrosis via targeting TNF-α signaling pathway and inhibiting the epithelial-mesenchymal transition.

Ma J, Ding L, Zang X, Wei R, Yang Y, Zhang W, Su H, Li X, Li M, Sun J, Zhang Z, Wang Z, Zhao D, Li X, Zhao L, Tong X
Frontiers in pharmacology 2024;15:1437231

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A disintegrin and metalloproteinase domain 10 expression inhibition by the small molecules adenosine, cordycepin and N6, N6-dimethyladenosine and immune regulation in malignant cancers.

Zhang W, Fu J, Du J, Liu X, Cheng J, Wei C, Xu Y, Fu J
Frontiers in immunology 2024;15:1434027

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Efficacy and safety evaluation of cross-reactive Fibroblast activation protein scFv-based CAR-T cells.

Niu W, Wang B, Zhang Y, Wang C, Cao J, Li J, He Y, Lei P
Frontiers in immunology 2024;15:1433679

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Development and validation of a glycolysis-associated gene signature for predicting the prognosis, immune landscape, and drug sensitivity in bladder cancer.

Shen C, Suo Y, Guo J, Su W, Zhang Z, Yang S, Wu Z, Fan Z, Zhou X, Hu H
Frontiers in immunology 2024;15:1430583

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Brozopine ameliorates cognitive impairment via upregulating Nrf2, antioxidation and anti-inflammation activities.

Fu Z, Wang X, Fan Y, Shang D, Zhang J, Xiao T, Guo J, Wang Y, Wang Z, Zhang Z, Jia Q, Zhu J, Jahromi AB, Meng Y, Gao N, Chang J, Gao Y
Frontiers in pharmacology 2024;15:1428455

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African swine fever virus structural protein p17 inhibits IRF3 activation by recruiting host protein PR65A and inducing apoptotic degradation of STING.

Wang S, Xiang Z, Gao P, Zhang Y, Zhou L, Ge X, Guo X, Han J, Yang H
Frontiers in microbiology 2024;15:1428233

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Xiaoyin-anshen formula alleviates psoriasis complicated by sleep disturbances by regulating melatonin, antioxidant enzymes, and pro-inflammatory cytokines in mice.

Zhu Z, Yin Q, Duan X
Frontiers in pharmacology 2024;15:1427985

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Identification and validation of glycolysis-related diagnostic signatures in diabetic nephropathy: a study based on integrative machine learning and single-cell sequence.

Wu X, Guo B, Chang X, Yang Y, Liu Q, Liu J, Yang Y, Zhang K, Ma Y, Fu S
Frontiers in immunology 2024;15:1427626

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VCAM1: an effective diagnostic marker related to immune cell infiltration in diabetic nephropathy.

Deng Y, Zhang S, Luo Z, He P, Ma X, Ma Y, Wang J, Zheng L, Tian N, Dong S, Zhang X, Zhang M
Frontiers in endocrinology 2024;15:1426913

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Puerarin ameliorates non-alcoholic fatty liver disease by inhibiting lipid metabolism through FMO5.

Li Z, Cao W, Zhang Y, Lai S, Ye Y, Bao J, Fu A
Frontiers in pharmacology 2024;15:1423634

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ASFV infection induces macrophage necroptosis and releases proinflammatory cytokine by ZBP1-RIPK3-MLKL necrosome activation.

Zhang D, Hao Y, Yang X, Shi X, Zhao D, Chen L, Liu H, Zhu Z, Zheng H
Frontiers in microbiology 2024;15:1419615

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Migrasome regulator TSPAN4 shapes the suppressive tumor immune microenvironment in pan-cancer.

Wang LJ, Xu R, Wu Y
Frontiers in immunology 2024;15:1419420

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Melatonin modulates neuroinflammatory response and microglial activation in mice exposed to dim blue light at night.

Song C, Suo Z, Wang Z, Cao J, Dong Y, Chen Y
Frontiers in pharmacology 2024;15:1416350

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The microglial innate immune receptor TREM2 participates in fear memory formation through excessive prelimbic cortical synaptic pruning.

Zhang LL, Cheng P, Chu YQ, Zhou ZM, Hua R, Zhang YM
Frontiers in immunology 2024;15:1412699

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LSD1 inhibition by tranylcypromine hydrochloride reduces alkali burn-induced corneal neovascularization and ferroptosis by suppressing HIF-1α pathway.

Deng Q, Gao Y, Wang Y, Mao J, Yan Y, Yang Z, Cong Y, Yang Y, Wan S
Frontiers in pharmacology 2024;15:1411513

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Comprehensive transcriptomic analysis identifies SLC25A4 as a key predictor of prognosis in osteosarcoma.

Zhang Y, Wang Y, Zhang W, Feng S, Xing Y, Wang T, Huang N, Li K, Zhang A
Frontiers in genetics 2024;15:1410145

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Pseudorabies virus tegument protein US2 antagonizes antiviral innate immunity by targeting cGAS-STING signaling pathway.

Kong Z, Chen X, Gong L, Wang L, Zhang Y, Guan K, Yao W, Kang Y, Lu X, Zhang Y, Du Y, Sun A, Zhuang G, Zhao J, Wan B, Zhang G
Frontiers in immunology 2024;15:1403070

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Circadian rhythm disruption-mediated downregulation of Bmal1 exacerbates DSS-induced colitis by impairing intestinal barrier.

Zhang Z, Li W, Han X, Tian D, Yan W, Liu M, Cao L
Frontiers in immunology 2024;15:1402395

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Involvement of autophagy in mesaconitine-induced neurotoxicity in HT22 cells revealed through integrated transcriptomic, proteomic, and m6A epitranscriptomic profiling.

Lin X, Zhang J, Wu Z, Shi Y, Chen M, Li M, Hu H, Tian K, Lv X, Li C, Liu Y, Gao X, Yang Q, Chen K, Zhu A
Frontiers in pharmacology 2024;15:1393717

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Kidney tea [Orthosiphon aristatus (Blume) Miq.] improves diabetic nephropathy via regulating gut microbiota and ferroptosis.

Zhou Z, Niu H, Bian M, Zhu C
Frontiers in pharmacology 2024;15:1392123

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TAK1 inhibition mitigates intracerebral hemorrhage-induced brain injury through reduction of oxidative stress and neuronal pyroptosis via the NRF2 signaling pathway.

Zhao J, Chen C, Ge L, Jiang Z, Hu Z, Yin L
Frontiers in immunology 2024;15:1386780

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Identification and validation of tryptophan-related gene signatures to predict prognosis and immunotherapy response in lung adenocarcinoma reveals a critical role for PTTG1.

Wang Z, Zhang J, Zuo C, Chen H, Wang L, Xie Y, Ma H, Min S, Wang X, Lian C
Frontiers in immunology 2024;15:1386427

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Epigenetically active chromatin in neonatal iWAT reveals GABPα as a potential regulator of beige adipogenesis.

Mooli RGR, Zhu B, Khan SR, Nagati V, Michealraj KA, Jurczak MJ, Ramakrishnan SK
Frontiers in endocrinology 2024;15:1385811

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PCBP1 interacts with the HTLV-1 Tax oncoprotein to potentiate NF-κB activation.

Su R, Kang X, Niu Y, Zhao T, Wang H
Frontiers in immunology 2024;15:1375168

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EMMPRIN promotes spheroid organization and metastatic formation: comparison between monolayers and spheroids of CT26 colon carcinoma cells.

Feigelman G, Simanovich E, Brockmeyer P, Rahat MA
Frontiers in immunology 2024;15:1374088

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Novel prognostic biomarker TBC1D1 is associated with immunotherapy resistance in gliomas.

Song D, Yang Q, Li L, Wei Y, Zhang C, Du H, Ren G, Li H
Frontiers in immunology 2024;15:1372113

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Identification of claudin-2 as a promising biomarker for early diagnosis of pre-diabetes.

Songtao Y, Fangyu L, Jie C, Li Y
Frontiers in pharmacology 2024;15:1370708

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Dysregulation of the 3β-hydroxysteroid dehydrogenase type 2 enzyme and steroid hormone biosynthesis in chronic kidney disease.

Zuo Y, Zha D, Zhang Y, Yang W, Jiang J, Wang K, Zhang R, Chen Z, He Q
Frontiers in endocrinology 2024;15:1358124

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Revealing the role of metformin in gastric intestinal metaplasia treatment.

Hu R, Xue X, Sun X, Mi Y, Wen H, Xi H, Li F, Zheng P, Liu S
Frontiers in pharmacology 2024;15:1340309

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A hypoxia-related genes prognostic risk model, and mechanisms of hypoxia contributing to poor prognosis through immune microenvironment and drug resistance in acute myeloid leukemia.

Liu X, Wang L, Kang Q, Feng C, Wang J
Frontiers in pharmacology 2024;15:1339465

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Genistein is effective in inhibiting Orf virus infection in vitro by targeting viral RNA polymerase subunit RPO30 protein.

Lv P, Fang Z, Guan J, Lv L, Xu M, Liu X, Li Z, Lan Y, Li Z, Lu H, Song D, He W, Gao F, Wang D, Zhao K
Frontiers in microbiology 2024;15:1336490

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TRIM56: a promising prognostic immune biomarker for glioma revealed by pan-cancer and single-cell analysis.

Wang B, Wang Z, Li Y, Shang Z, Liu Z, Fan H, Zhan R, Xin T
Frontiers in immunology 2024;15:1327898

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Uncovering the role of FXYD3 as a potential oncogene and early biomarker in pancreatic cancer.

Yee KX, Lee YC, Nguyen HD, Chen MY, Ni YC, Wu YF, Lee KH
American journal of cancer research 2024;14(9):4353-4366

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An injectable magnesium-loaded hydrogel releases hydrogen to promote osteoporotic bone repair via ROS scavenging and immunomodulation.

Zhou H, He Z, Cao Y, Chu L, Liang B, Yu K, Deng Z
Theranostics 2024;14(9):3739-3759

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Nicotinamide phosphoribosyltransferase prompts bleomycin-induced pulmonary fibrosis by driving macrophage M2 polarization in mice.

Chen Y, Wang T, Liang F, Han J, Lou Z, Yu Y, Li J, Zhan T, Gu Y, Dong L, Jiang B, Zhang W, Wu M, Lu Y
Theranostics 2024;14(7):2794-2815

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Single-cell RNA sequencing reveals S100a9(hi) macrophages promote the transition from acute inflammation to fibrotic remodeling after myocardial ischemia‒reperfusion.

Shen S, Zhang M, Wang X, Liu Q, Su H, Sun B, Guo Z, Tian B, Gan H, Gong C, Ma L
Theranostics 2024;14(3):1241-1259

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Ginsenoside Rg3 decreases breast cancer stem-like phenotypes through impairing MYC mRNA stability.

Ning JY, Zhang ZH, Zhang J, Liu YM, Li GC, Wang AM, Li Y, Shan X, Wang JH, Zhang X, Zhao Y
American journal of cancer research 2024;14(2):601-615

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Vagal innervation limits brain injury by inhibiting gut-selective integrin-mediated intestinal immunocyte migration in intracerebral hemorrhage.

Fu P, Zong Y, Dai Y, Zhu L, Chen S, Rastegar-Kashkooli Y, Wang J, Zhang J, Wang J, Jiang C
Theranostics 2024;14(19):7383-7404

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Circular RNA SCMH1 suppresses KMO expression to inhibit mitophagy and promote functional recovery following stroke.

Wang Y, Bai Y, Cai Y, Zhang Y, Shen L, Xi W, Zhou Z, Xu L, Liu X, Han B, Yao H
Theranostics 2024;14(19):7292-7308

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Decreased lncRNA HNF4A-AS1 facilitates resistance to sorafenib-induced ferroptosis of hepatocellular carcinoma by reprogramming lipid metabolism.

Zhao Y, Han S, Zeng Z, Zheng H, Li Y, Wang F, Huang Y, Zhao Y, Zhuo W, Lv G, Wang H, Zhao G, Zhao E, Hu Y, Hu P, Zhao G
Theranostics 2024;14(18):7088-7110

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Macrophage membrane‒biomimetic nanoparticles target inflammatory microenvironment for epilepsy treatment.

Geng C, Ren X, Cao P, Chu X, Wei P, Liu Q, Lu Y, Fu B, Li W, Li Y, Zhao G
Theranostics 2024;14(17):6652-6670

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Polydatin ameliorates low-density lipoprotein cholesterol and lipid metabolism by downregulating proprotein convertase subtilisin/kexin type 9 (PCSK9) in triple-negative breast cancer with hyperlipidemia.

Liu M, Zhang Q
American journal of cancer research 2024;14(1):52-72

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Histone deacetylase 3-specific inhibitor RGFP966 attenuates oxidative stress and inflammation after traumatic brain injury by activating the Nrf2 pathway.

Xu L, An T, Jia B, Wu Q, Shen J, Jin J, Liu J, Li C
Burns & trauma 2024;12:tkad062

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ALKBH5 modulation of ferroptosis in recurrent miscarriage: implications in cytotrophoblast dysfunction.

Qin C, Wu J, Wei X, Liu X, Lin Y
PeerJ 2024;12:e18227

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ULK2 suppresses ovarian cancer cell migration and invasion by elevating IGFBP3.

Chen X, Shao C, Liu J, Sun H, Yao B, Ma C, Xu H, Zhu W
PeerJ 2024;12:e17628

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The expression and clinical significance of serine hydroxymethyltransferase2 in gastric cancer.

Shan Y, Liu D, Li Y, Wu C, Ye Y
PeerJ 2024;12:e16594

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The role of PCBP1 in carbon ion-induced ferroptosis and inhibition of lung adenocarcinoma proliferation.

Kang Z, Fu Z, Tian X, Geng Y, Zhang Q, Liu Y, Wang X, Luo H, Yang Z
Frontiers in public health 2024;12:1496439

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Electroacupuncture Alleviates Obesity and Insulin Resistance via the GLP-1-VTADA Reward Circuit.

Zhu Y, Tian J, Wei X, Jia S, Shu Q
Neuroendocrinology 2024;114(3):263-278

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Identification and validation of five ferroptosis-related molecular signatures in keloids based on multiple transcriptome data analysis.

Sun Z, Qin Y, Zhang X
Frontiers in molecular biosciences 2024;11:1490745

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Mechanism of medical hemorrhoid gel in relieving pruritus ani via inhibiting the activation of JAK2/STAT3 pathway.

Ai Z, Yuan D, Cai J, Dong R, Liu W, Zhou D
Frontiers in medicine 2024;11:1487531

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Hydrogen peroxide disrupts the regulatory pathway of saliva secretion in two salivary acinar rat cell lines.

Golnarnik G, Søland TM, Galtung HK, Haug TM
Frontiers in molecular biosciences 2024;11:1480721

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ACSS2 enables melanoma cell survival and tumor metastasis by negatively regulating the Hippo pathway.

Zhang B, Zhu Q, Qu D, Zhao M, Du J, Zhang H, Wang H, Jiang L, Yi X, Guo S, Wang H, Yang Y, Guo W
Frontiers in molecular biosciences 2024;11:1423795

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Bioinformatics analysis and experimental verification of TIGD1 in non-small cell lung cancer.

Xia L, Yang Z, Xv M, Wang G, Mao Y, Yang Y, Tang J
Frontiers in medicine 2024;11:1374260

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Deubiquitinating Enzyme USP19 Regulates Ferroptosis and Mitochondrial Damage in SH-SY5Y Cells by Targeting the NOX4 Protein.

Yu W, Zhuang S, Zhan M, Chen Y, Zhang J, Chen L, Tu C, Zheng L, Chen S
Journal of Alzheimer's disease : JAD 2024;100(3):799-808

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IGF2BP2 modulates autophagy and serves as a prognostic marker in glioma.

Li N, Deng L, Zhang Y, Tang X, Lei B, Zhang Q
Ibrain 2024 Spring;10(1):19-33

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Propionate-producing engineered probiotics ameliorated murine ulcerative colitis by restoring anti-inflammatory macrophage via the GPR43/HDAC1/IL-10 axis.

Kang G, Wang X, Gao M, Wang L, Feng Z, Meng S, Wu J, Zhu Z, Gao X, Cao X, Huang H
Bioengineering & translational medicine 2024 Sep;9(5):e10682

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Induction of apoptosis by oridonin in nonfunctioning pituitary adenoma cells.

Chen HT, Yuan XY, Wang ZY, Fan D, Luo XM, Yang JH, Ma YX, Liu J, Wang X, Wang ZM
Drug development research 2024 Sep;85(6):e22251

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FOXM1 Upregulates O-GlcNAcylation Level Via The Hexosamine Biosynthesis Pathway to Promote Angiogenesis in Hepatocellular Carcinoma.

Zhang X, Zhong Y, Yang Q
Cell biochemistry and biophysics 2024 Sep;82(3):2767-2785

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Increased expression of SLC25A18 is associated with Alzheimer's disease and is involved in Aβ42-induced mitochondrial dysfunction and apoptosis in neuronal cells.

Song JY, Jia Y, Han H, Yang XH, Zhang J, Zhang Q, Wang SS, Wang CY, Chen L, Zhang M
Mitochondrion 2024 Sep;78:101918

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Transplantation of astrocyte-derived mitochondria into injured astrocytes has a protective effect following stretch injury.

Gong QY, Wang W, Cai L, Jing Y, Yang DX, Yuan F, Tian HL, Ding J, Chen H, Xu ZM
Mitochondrion 2024 Sep;78:101902

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A reciprocal relationship between mitochondria and lipid peroxidation determines the chondrocyte intracellular redox environment.

Hines MR, Gomez-Contreras PC, Liman S, Wilson AM, Lu KJ, O'Neill JA, Fisher JS, Fredericks DC, Wagner BA, Buettner GR, Van Remmen H, Coleman MC
Redox biology 2024 Sep;75:103306

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Vitamin E and GPX4 cooperatively protect treg cells from ferroptosis and alleviate intestinal inflammatory damage in necrotizing enterocolitis.

Luo S, Zeng Y, Chen B, Yan J, Ma F, Zhuang G, Hao H, Cao G, Xiao X, Li S
Redox biology 2024 Sep;75:103303

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Sodium Houttuyfonate Alleviates Monocrotaline-induced Pulmonary Hypertension by Regulating Orai1 and Orai2.

Zhang J, Dong F, Ju G, Pan X, Mao X, Zhang X
American journal of respiratory cell and molecular biology 2024 Sep;71(3):332-342

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Expression Characteristics, Immune Signature, and Prognostic Value of the SOCS Family Identified by Multiomics Integrative Analysis in Liver Cancer.

Dong Z, Dai B, Wu R, Fang K, Sui C, Geng L, Yang J
Cancer reports (Hoboken, N.J.) 2024 Sep;7(9):e2161

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Exosomes Derived from Meningitic Escherichia coli-Infected Brain Microvascular Endothelial Cells Facilitate Astrocyte Activation.

Yang R, Qu X, Zhi S, Wang J, Fu J, Tan C, Chen H, Wang X
Molecular neurobiology 2024 Sep;61(9):7195-7210

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Low-Dose LPS Modulates Microglia/Macrophages Phenotypic Transformation to Amplify Rehabilitation Effects in Chronic Spinal Cord Injured (CSCI) Mice.

Zhong J, He Y, Zhao Q, Luo H, Zhang Q, Tian Y, Liu Y, Yang C, Yin Y, Yu L, Pan L, Tan B
Molecular neurobiology 2024 Sep;61(9):6484-6500

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Integrative proteogenomic profiling of high-risk prostate cancer samples from Chinese patients indicates metabolic vulnerabilities and diagnostic biomarkers.

Dong B, Xu JY, Huang Y, Guo J, Dong Q, Wang Y, Li N, Liu Q, Zhang M, Pan Q, Wang H, Jiang J, Chen B, Shen D, Ma Y, Zhai L, Zhang J, Li J, Xue W, Tan M, Qin J
Nature cancer 2024 Sep;5(9):1427-1447

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Effects of catechin on the malignant biological behavior of gastric cancer cells through the PI3K/Akt signaling pathway.

Ding Y, Li H, Cao S, Yu Y
Toxicology and applied pharmacology 2024 Sep;490:117036

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Vitamin D Relieves Epilepsy Symptoms and Neuroinflammation in Juvenile Mice by Activating the mTOR Signaling Pathway via RAF1: Insights from Network Pharmacology and Molecular Docking Studies.

Lu T, Chen X, Zhang Q, Shang K, Yang X, Xiang W
Neurochemical research 2024 Sep;49(9):2379-2392

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PLEK2 activates the PI3K/AKT signaling pathway to drive lung adenocarcinoma progression by upregulating SPC25.

Zhang W, Yu L, Xu C, Tang T, Cao J, Chen L, Pang X, Ren W
Cell biology international 2024 Sep;48(9):1285-1300

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The prognostic value and its relationship with immune infiltration of ACLY in clear cell renal cell carcinoma.

Yin B, Liu Q, Zheng Y, Gao H, Lin Y, Zhao Z
Translational oncology 2024 Sep;47:102056

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Restoration of HMGCS2-mediated ketogenesis alleviates tacrolimus-induced hepatic lipid metabolism disorder.

Li SL, Zhou H, Liu J, Yang J, Jiang L, Yuan HM, Wang MH, Yang KS, Xiang M
Acta pharmacologica Sinica 2024 Sep;45(9):1898-1911

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mtDNA amplifies beryllium sulfate-induced inflammatory responses via the cGAS-STING pathway in 16HBE cells.

Liu X, Jiang T, Jin H, Yan C, Tong Y, Ding J, Li Y, Huang L, Zhang Z
Journal of applied toxicology : JAT 2024 Sep;44(9):1403-1415

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Engineered targeting OIP5 sensitizes bladder cancer to chemotherapy resistance via TRIP12-PPP1CB-YBX1 axis.

Wang X, Guo T, Niu L, Zheng B, Huang W, Xu H, Huang W
Oncogene 2024 Sep;43(38):2850-2867

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Circ_0004674 regulation of glycolysis and proliferation mechanism of osteosarcoma through miR-140-3p/TCF4 pathway.

Ma Y, Du S, Wang S, Liu X, Cong L, Shen W, Ye K
Journal of biochemical and molecular toxicology 2024 Sep;38(9):e23846

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Astragaloside IV protects renal tubular epithelial cells against oxidative stress-induced injury by upregulating CPT1A-mediated HSD17B10 lysine succinylation in diabetic kidney disease.

Wang M, Li Q, Wang S, Zuo L, Hai Y, Yuan S, Li X, Huang X, Yang C, Yao L, Cao W, Zuo G, Wang J
Phytotherapy research : PTR 2024 Sep;38(9):4519-4540

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Evaluation of Pregabalin bioadhesive multilayered microemulsion IOP-lowering eye drops.

Maria DN, Ibrahim MM, Kim MJ, Maria SN, White WA, Wang X, Hollingsworth TJ, Jablonski MM
Journal of controlled release : official journal of the Controlled Release Society 2024 Sep;373:667-687

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In Situ Triggered Self-Contraction Bioactive Microgel Assembly Accelerates Diabetic Skin Wound Healing by Activating Mechanotransduction and Biochemical Pathway.

Xie Q, Yan C, Liu G, Bian L, Zhang K
Advanced materials (Deerfield Beach, Fla.) 2024 Sep;36(38):e2406434

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Lipo/TK-CDN/TPP/Y6 nanoparticles inhibit cutaneous melanoma formation.

Xiao A, Yin L, Chen T, Qian H
Journal of drug targeting 2024 Sep;32(8):931-940

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Ubiquitin-specific protease 1 facilitates hepatocellular carcinoma progression by modulating mitochondrial fission and metabolic reprogramming via cyclin-dependent kinase 5 stabilization.

Bian S, Ni W, Zhou L, Tong Y, Dai C, Zhao X, Qiang Y, Gao J, Xiao Y, Liu W, Chen C, Lin S, Gong J, Zhao S, Chen Y, Lin Z, Liu D, Zhao H, Zheng W
Cell death and differentiation 2024 Sep;31(9):1202-1218

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Hinokiflavone resists HFD-induced obesity by promoting apoptosis in an IGF2BP2-mediated Bim m(6)A modification dependent manner.

Wang M, Chao M, Han H, Zhao T, Yan W, Yang G, Pang W, Cai R
The Journal of biological chemistry 2024 Sep;300(9):107721

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Classical apoptotic stimulus, staurosporine, induces lytic inflammatory cell death, PANoptosis.

Sarkar R, Choudhury SM, Kanneganti TD
The Journal of biological chemistry 2024 Sep;300(9):107676

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USP7 deubiquitinates epigenetic reader ZMYND8 to promote breast cancer cell migration and invasion.

Tang K, Yin T, Deng B, Wang M, Ren Z, Wang S, Liu X, Li H, Wang J, Du Y, Zhou J, Chen Y, Wang Y
The Journal of biological chemistry 2024 Sep;300(9):107672

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Cyclophilin J limits linear ubiquitin signaling and controls colorectal cancer progression.

Sheng C, Yao C, Wang J, Mao Y, Fu L, Chen S
The Journal of biological chemistry 2024 Sep;300(9):107610

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Activation of Piezo1 by intracranial hypertension induced neuronal apoptosis via activating hippo pathway.

Zeng J, Fang Z, Duan J, Zhang Z, Wang Y, Wang Y, Chen L, Wang J, Liu F
CNS neuroscience & therapeutics 2024 Sep;30(9):e14872

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MitoAMPK inhibits the Warburg effect by MZF1-SIRT6 with glycosis related genes in NSCLC.

Li S, He J, Zhang L, Zhao Q, Zhao S, Jiang S
Journal of cellular and molecular medicine 2024 Sep;28(17):e70053

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Blue light photobiomodulation induced osteosarcoma cell death by facilitating ferroptosis and eliciting an incomplete tumor cell stress response.

Yang J, Fu Q, Jiang H, Zhong H, Qin HK, Miao X, Li Y, Liu M, Yao J
Journal of photochemistry and photobiology. B, Biology 2024 Sep;258:113003

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Microglia Caspase11 non-canonical inflammasome drives fever.

Yu P, Li Y, Fu W, Yu X, Sui D, Xu H, Sun W
Acta physiologica (Oxford, England) 2024 Sep;240(9):e14187

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ARL13B promotes cell cycle through the sonic hedgehog signaling pathway to alleviate nerve damage during cerebral ischemia/reperfusion in rats.

Jiang L, Yang S, Deng L, Luo J, Zhang X, Chen S, Dong Z
Biochemical pharmacology 2024 Sep;227:116446

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Inhibition of PLA2G4A attenuated valproic acid- induced lysosomal membrane permeabilization and restored impaired autophagic flux: Implications for hepatotoxicity.

Wang ML, Zhang YJ, He DL, Li T, Zhao MM, Zhao LM
Biochemical pharmacology 2024 Sep;227:116438

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NOX1 triggers ferroptosis and ferritinophagy, contributes to Parkinson's disease.

Wang H, Mao W, Zhang Y, Feng W, Bai B, Ji B, Chen J, Cheng B, Yan F
Free radical biology & medicine 2024 Sep;222:331-343

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Activation of LONP1 by 84-B10 alleviates aristolochic acid nephropathy via re-establishing mitochondrial and peroxisomal homeostasis.

Xu X, Zhu W, Miao M, Bai M, Fan J, Niu Y, Li Y, Zhang A, Jia Z, Wu M
Chinese journal of natural medicines 2024 Sep;22(9):808-821

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Zinc-Mediated Endoplasmic Reticulum Stress and Metallothionein Alleviate Arsenic-Induced Cardiotoxicity in Cyprinus Carpio.

Dong H, Song H, Liu Y, Zou H
Biological trace element research 2024 Sep;202(9):4203-4215

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Ferroptosis is involved in quercetin-mediated alleviation of Ochratoxin A-induced kidney damage.

Zhou Y, Lu W, Huang K, Gan F
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Sep;191:114877

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Mefunidone alleviates silica-induced inflammation and fibrosis by inhibiting the TLR4-NF-κB/MAPK pathway and attenuating pyroptosis in murine macrophages.

Long L, Dai X, Yao T, Zhang X, Jiang G, Cheng X, Jiang M, He Y, Peng Z, Hu G, Tao L, Meng J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117216

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IL-17A enhances the inflammatory response of glaucoma through Act1/TRAF6/NF-κB pathway.

Zheng Y, Mou Z, Tan S, Wang X, Yuan J, Li H
Neurochemistry international 2024 Sep;178:105787

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The MondoA-dependent TXNIP/GDF15 axis predicts oxaliplatin response in colorectal adenocarcinomas.

Deng J, Pan T, Wang D, Hong Y, Liu Z, Zhou X, An Z, Li L, Alfano G, Li G, Dolcetti L, Evans R, Vicencio JM, Vlckova P, Chen Y, Monypenny J, Gomes CAC, Weitsman G, Ng K, McCarthy C, Yang X, Hu Z, Porter JC, Tape CJ, Yin M, Wei F, Rodriguez-Justo M, Zhang J, Tejpar S, Beatson R, Ng T
EMBO molecular medicine 2024 Sep;16(9):2080-2108

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Combining the novel FLT3 and MERTK dual inhibitor MRX-2843 with venetoclax results in promising antileukemic activity against FLT3-ITD AML.

Wu S, Liu F, Gai Y, Carter J, Edwards H, Hüttemann M, Wang G, Li C, Taub JW, Wang Y, Ge Y
Leukemia research 2024 Sep;144:107547

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Molecular glue triggers degradation of PHGDH by enhancing the interaction between DDB1 and PHGDH.

Huang Z, Zhang K, Jiang Y, Wang M, Li M, Guo Y, Gao R, Li N, Wang C, Chen J, Wang J, Liu N, Liu X, Liu S, Wei M, Yang C, Yang G
Acta pharmaceutica Sinica. B 2024 Sep;14(9):4001-4013

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Withaferin A protects against epilepsy by promoting LCN2-mediated astrocyte polarization to stopping neuronal ferroptosis.

Zhou Z, Zhang P, Ya D, Liu J, Xu Y, Zhang Y, Tang W, Zhou D, Liao R, Liu L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155892

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Daphnetin induces ferroptosis in ovarian cancer by inhibiting NAD(P)H:Quinone oxidoreductase 1 (NQO1).

Ma N, Zhang M, Hu J, Wei Z, Zhang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155876

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Rice bran active peptide (RBAP) inhibited macrophage differentiation to foam cell and atherosclerosis in mice via regulating cholesterol efflux.

Mu J, Lin Q, Chen Y, Wang J, Yu X, Huang F, Liu X, Fang Y, Li Y, Zhu B, Liang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155864

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Theabrownin from Pu-erh Tea Improves DSS-Induced Colitis via Restoring Gut Homeostasis and Inhibiting TLR2&4 Signaling Pathway.

Zhao L, Zhao C, Miao Y, Lei S, Li Y, Gong J, Peng C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155852

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Luteolin ameliorates hypoxic pulmonary vascular remodeling in rat via upregulating K(V)1.5 of pulmonary artery smooth muscle cells.

Zhang Z, Chen J, Su S, Xie X, Ji L, Li Z, Lu D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155840

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PRM1201 effectively inhibits colorectal cancer metastasis via shaping gut microbiota and short- chain fatty acids.

Jia R, Shao S, Zhang P, Yuan Y, Rong W, An Z, Lv S, Feng Y, Liu N, Feng Q, Wang Y, Li Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155795

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Oxysophoridine inhibits oxidative stress and inflammation in hepatic fibrosis via regulating Nrf2 and NF-κB pathways.

Chen JY, Yang YJ, Meng XY, Lin RH, Tian XY, Zhang Y, Lai WF, Yang C, Ma XQ, Huang MQ
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155585

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Notch-Targeted Therapeutic in Colorectal Cancer by Notch1 Attenuation Via Tumor Microenvironment-Responsive Cascade DNA Delivery.

Lu Y, Cao Y, Guo X, Gao Y, Chen X, Zhang Z, Ge Z, Chu D
Advanced healthcare materials 2024 Sep;13(22):e2400797

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Hypermethylation and low expression of FOXM1 predisposes women to unexplained recurrent miscarriage by impairing trophoblast stem cell proliferation.

Jiang Y, Zhu H, Wang T, Tong H, Liu J, Yang Y, Zhou X, Liu X
Cellular signalling 2024 Sep;121:111259

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Knockdown of programmed cell death factor 4 restores erectile function by attenuating apoptosis in rats with bilateral cavernous nerve crush injury.

Ge Y, Xia T, Feng Z, Xi Y, Hu D, Hong Y, Tang B, Wu J, Chen J, Xiao H
Andrology 2024 Sep;12(6):1439-1448

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Microbial Tryptophan Metabolites Ameliorate Ovariectomy-Induced Bone Loss by Repairing Intestinal AhR-Mediated Gut-Bone Signaling Pathway.

Chen C, Cao Z, Lei H, Zhang C, Wu M, Huang S, Li X, Xie D, Liu M, Zhang L, Chen G
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(36):e2404545

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KAT6A Condensates Impair PARP1 Trapping of PARP Inhibitors in Ovarian Cancer.

Zhan Z, Zhang J, Liang H, Wang C, Hong L, Liu W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(34):e2400140

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Isoquercetin Ameliorates Osteoarthritis via Nrf2/NF-κB Axis: An In Vitro and In Vivo Study.

Yu H, Lou J, Ni L, Yan M, Zhu K, Mao S, Zhu J
Chemical biology & drug design 2024 Sep;104(3):e14620

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Novel goose parvovirus VP1 targets IRF7 protein to block the type I interferon upstream signaling pathway.

Yang YT, Deng ZC, Zhang LJ, Fu XL, Fu C, Zhan XZ, Tian YB, Liu WJ
Poultry science 2024 Sep;103(9):104065

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ELOVL5 and VLDLR synergistically affect n-3 PUFA deposition in eggs of different chicken breeds.

Jiang C, Shi Y, Shi X, Yan J, Xuan L, Zhuang L, Li J, Xu G, Zheng J
Poultry science 2024 Sep;103(9):104016

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Effects of maternal hawthorn-leaf flavonoid supplementation on the intestinal development of offspring chicks.

Dai H, Huang Z, Shi F, Li S, Zhang Y, Wu H, Lv Z
Poultry science 2024 Sep;103(9):103969

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Canthin-6-one analogs block Newcastle disease virus proliferation via suppressing the Akt and ERK pathways.

Wang C, Wang T, Dai J, Han Y, Hu R, Li N, Yang Z, Wang J
Poultry science 2024 Sep;103(9):103944

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The developmental pattern related to fatty acid uptake and oxidation in the yolk sac membrane and jejunum during embryogenesis in Muscovy duck.

Li H, Zhang X, Wang X, Wu Q, Zheng W, Liu C, Wei S, Zuo X, Xiao W, Ye H, Wang W, Yang L, Zhu Y
Poultry science 2024 Sep;103(9):103929

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A novel UVA-associated circUBE2I mediates ferroptosis in HaCaT cells.

Yi P, Huang Y, Zhao X, Qin Z, Zhu D, Liu L, Zheng Y, Feng J, Long M
Photochemistry and photobiology 2024 Sep-Oct;100(5):1365-1377

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Metabolomics reveals the implication of acetoacetate and ketogenic diet therapy in radioiodine-refractory differentiated thyroid carcinoma.

Wang J, Xu Q, Xuan Z, Mao Y, Tang X, Yang K, Song F, Zhu X
The oncologist 2024 Sep 6;29(9):e1120-e1131

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AC092100.1 promotes angiogenesis in pre-eclampsia through YTHDC2/VEGFA signaling.

Yong W, Jian Y, Wang Q, Fei K, Li P
Functional & integrative genomics 2024 Sep 6;24(5):157

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Targeting stress induction of GRP78 by cardiac glycoside oleandrin dually suppresses cancer and COVID-19.

Ha DP, Shin WJ, Liu Z, Doche ME, Lau R, Leli NM, Conn CS, Russo M, Lorenzato A, Koumenis C, Yu M, Mumenthaler SM, Lee AS
Cell & bioscience 2024 Sep 6;14(1):115

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PRKDC Induces Chemoresistance in Osteosarcoma by Recruiting GDE2 to Stabilize GNAS and Activate AKT.

Zhang W, Li W, Yin C, Feng C, Liu B, Xu H, Jin X, Tu C, Li Z
Cancer research 2024 Sep 4;84(17):2873-2887

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Selenomethionine Promotes Milk Protein and Fat Synthesis and Proliferation of Mammary Epithelial Cells through the GPR37-mTOR-S6K1 Signaling.

Zhang J, Xie L, Li H, Li S, Gao X, Zhang M
Journal of agricultural and food chemistry 2024 Sep 4;72(35):19505-19516

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Pericentriolar material 1 promotes intestinal inflammation in ulcerative colitis by activating NLRP3/gasdermin D-mediated macrophage pyroptosis.

Niu J, Wen Y, Zhang F, Li S, Miao J, Liang H, Bai X, Zeng Z, Guo X, Miao Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Sep 30;38(18):e70054

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Effects of Mao tea from Nankun Mountain on nonalcoholic fatty liver disease in mice.

Zhang W, Feng L, Li P, Wang A, Dai C, Qi Y, Lu J, Xu X
Food & function 2024 Sep 30;15(19):9863-9879

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Macrophage WNK1 senses intracellular hypo-chlorine to regulate vulnerability to sepsis attack during hypochloremia.

Yin T, He L, Du Y, Liu J, Peng L, Yang M, Sun S, Liu J, Li J, Cao J, Zhu H, Wang S
International immunopharmacology 2024 Sep 30;139:112721

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Eupatilin suppresses osteoclastogenesis and periodontal bone loss by inhibiting the MAPKs/Siglec-15 pathway.

Zhao B, Chen Z, Li T, Yao H, Wang Z, Liao Y, Guo H, Fu D, Ji Y, Du M
International immunopharmacology 2024 Sep 30;139:112720

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Andrographolide ameliorates sepsis-induced acute lung injury by promoting autophagy in alveolar macrophages via the RAGE/PI3K/AKT/mTOR pathway.

Qin Y, Li W, Liu J, Wang F, Zhou W, Xiao L, Zhou P, Wu F, Chen X, Xu S, Liu L, Xiao X, Zhang D
International immunopharmacology 2024 Sep 30;139:112719

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Adipose-derived mesenchymal stromal cells alleviate intestinal fibrosis: The role of tumor necrosis factor-stimulated gene 6 protein.

Li X, Chen J, Xie M, Xiong Z, Yin S, Jin L, Yu Z, Wang C, Zhang F, Luo D, Guo J, Huang D, Tang H, Chen H, Lan P, Lian L
International immunopharmacology 2024 Sep 30;139:112693

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A novel signature constructed by cuproptosis-related RNA methylation regulators suggesting downregulation of YTHDC2 may induce cuproptosis resistance in colorectal cancer.

Zhao Z, Miao Z, Hou Y, Zhong Y, Zhang X, Fang X
International immunopharmacology 2024 Sep 30;139:112691

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Inhibitors of APE1 redox and ATM synergistically sensitize osteosarcoma cells to ionizing radiation by inducing ferroptosis.

Xiao H, Jiang N, Zhang H, Wang S, Pi Q, Chen H, He X, Luo W, Lu Y, Deng Y, Zhong Z
International immunopharmacology 2024 Sep 30;139:112672

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NOSTRIN is involved in benign prostatic hyperplasia via inhibition of proliferation, oxidative stress, and inflammation in prostate epithelial cells.

Li S, Yu C, Xiao H, Xu Q, Gao B, Guo L, Sun Z, Liu J
Translational andrology and urology 2024 Sep 30;13(9):2055-2069

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Silencing of TXNIP attenuates oxidative stress injury in HEI-OC1 by inhibiting the activation of NLRP3 and NF-κB.

Ma N, Xia L, Zheng Z, Chen X, Xing W, Feng Y
Heliyon 2024 Sep 30;10(18):e37753

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Fatty acid synthase (FASN) is a tumor-cell-intrinsic metabolic checkpoint restricting T-cell immunity.

Cuyàs E, Pedarra S, Verdura S, Pardo MA, Espin Garcia R, Serrano-Hervás E, Llop-Hernández À, Teixidor E, Bosch-Barrera J, López-Bonet E, Martin-Castillo B, Lupu R, Pujana MA, Sardanyès J, Alarcón T, Menendez JA
Cell death discovery 2024 Sep 30;10(1):417

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SLC7A11-mediated cystine import protects against NDUFS7 deficiency-induced cell death in HEK293T cells.

Chen J, Gao L
Biochemical and biophysical research communications 2024 Sep 3;723:150178

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RTP4 Enhances Corneal HSV-1 Infection in Mice With Type 2 Diabetes Mellitus.

Dai Y, Mao S, Zang X, Ge H, Feng J, Wang Y, Qi X, Yang L, Zhou Q, Wang X
Investigative ophthalmology & visual science 2024 Sep 3;65(11):36

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Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation.

Zhou J, Zhang L, Peng J, Zhang X, Zhang F, Wu Y, Huang A, Du F, Liao Y, He Y, Xie Y, Gu L, Kuang C, Ou W, Xie M, Tu T, Pang J, Zhang D, Guo K, Feng Y, Yin S, Cao Y, Li T, Jiang Y
Cell metabolism 2024 Sep 3;36(9):2054-2068.e14

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Reduced levels of MRE11 cause disease phenotypes distinct from ataxia telangiectasia-like disorder.

Hartlerode AJ, Mostafa AM, Orban SK, Benedeck R, Campbell K, Hoenerhoff MJ, Ferguson DO, Sekiguchi JM
Human molecular genetics 2024 Sep 3;33(18):1605-1617

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Asparagine Availability Is a Critical Limiting Factor for Infectious Spleen and Kidney Necrosis Virus Replication.

Ma B, Li F, Fu X, Luo X, Lin Q, Liang H, Niu Y, Li N
Viruses 2024 Sep 29;16(10)

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Epigenetic reader ZMYND11 noncanonical function restricts HNRNPA1-mediated stress granule formation and oncogenic activity.

Lian C, Zhang C, Tian P, Tan Q, Wei Y, Wang Z, Zhang Q, Zhang Q, Zhong M, Zhou LQ, Ke X, Zhang H, Zhu Y, Li Z, Cheng J, Wei GH
Signal transduction and targeted therapy 2024 Sep 28;9(1):258

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Development of T follicular helper cell-independent nanoparticle vaccines for SARS-CoV-2 or HIV-1 by targeting ICOSL.

Zhang Y, Chen A, Li D, Yuan Q, Zhu A, Deng J, Wang Y, Liu J, Liang C, Li W, Fang Q, Xie J, Zhang X, Zhang X, Zhang Y, Chen R, Pan T, Zhang H, He X
NPJ vaccines 2024 Sep 28;9(1):176

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Serotonylation in tumor-associated fibroblasts contributes to the tumor-promoting roles of serotonin in colorectal cancer.

Ling T, Dai Z, Wang H, Kien TT, Cui R, Yu T, Chen J
Cancer letters 2024 Sep 28;600:217150

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Integrated bioinformatics analysis identifies PCSK9 as a prognosticator correlated with lipid metabolism in pancreatic adenocarcinoma.

Zhou S, Guo Q, Chen A, Li X, Zou X
World journal of surgical oncology 2024 Sep 28;22(1):256

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Aldo-Keto reductase 1C3 reduces myocardial cell damage after acute myocardial infarction by activating the Kelch-like ECH-associated protein 1-nuclear factor erythroid 2-related factor 2-antioxidant response element pathway to inhibit ferroptosis.

Miao W, Hu YZ
Journal of geriatric cardiology : JGC 2024 Sep 28;21(9):899-912

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SIRT6 modulates lesion microenvironment in LPC induced demyelination by targeting astrocytic CHI3L1.

Du J, Yin Y, Wu D, Diao C, Zhao T, Peng F, Li N, Wang D, Shi J, Wang L, Kong L, Zhou W, Hao A
Journal of neuroinflammation 2024 Sep 28;21(1):243

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Deletion of ASPP1 in myofibroblasts alleviates myocardial fibrosis by reducing p53 degradation.

Li S, Yang M, Zhao Y, Zhai Y, Sun C, Guo Y, Zhang X, Zhang L, Tian T, Yang Y, Pei Y, Li J, Li C, Xuan L, Li X, Zhao D, Yang H, Zhang Y, Yang B, Zhang Z, Pan Z, Lu Y
Nature communications 2024 Sep 28;15(1):8425

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Anlotinib reverses osimertinib resistance by inhibiting epithelial-to-mesenchymal transition and angiogenesis in non-small cell lung cancer.

Lyu L, Hua X, Liu J, Zhan S, Zhang Q, Liang X, Feng J, Song Y
Journal of biomedical research 2024 Sep 27;39(5):452-466

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mTOR/miR-142-3p/PRAS40 signaling cascade is critical for tuberous sclerosis complex-associated renal cystogenesis.

Zhao S, Hao S, Zhou J, Chen X, Zhang T, Qi Z, Zhang T, Jalal S, Zhai C, Yin L, Bo Y, Teng H, Wang Y, Gao D, Zhang H, Huang L
Cellular & molecular biology letters 2024 Sep 27;29(1):125

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Bioinformatics analysis of ferroptosis in frozen shoulder.

Zhang H, Zhou J, Liu Z, Wang K, Jiang H
BMC medical genomics 2024 Sep 27;17(1):234

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High mobility group box-1 protein promotes astrocytic CCL5 production through the MAPK/NF-κB pathway following spinal cord injury.

Chi G, Lu J, He T, Wang Y, Zhou X, Zhang Y, Qiu L
Scientific reports 2024 Sep 27;14(1):22344

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The Involvement of Endoplasmic Reticulum Stress during the Interaction between Calcium Oxalate Crystals and Renal Tubular Epithelial Cells.

Hong SY, Miao LT, Qin BL
Biology 2024 Sep 27;13(10)

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Qin-Yu-Qing-Chang decoction reshapes colonic metabolism by activating PPAR-γ signaling to inhibit facultative anaerobes against DSS-induced colitis.

Xu F, Hu J, Li Y, Cheng C, Au R, Tong Y, Wu Y, Cui Y, Fang Y, Chen H, Zhu L, Shen H
Chinese medicine 2024 Sep 26;19(1):130

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The human ciliopathy protein RSG1 links the CPLANE complex to transition zone architecture.

Vazquez N, Lee C, Valenzuela I, Phan TP, Derderian C, Chávez M, Mooney NA, Demeter J, Aziz-Zanjani MO, Cusco I, Codina M, Martínez-Gil N, Valverde D, Solarat C, Buel AL, Thauvin-Robinet C, Steichen E, Filges I, Joset P, De Geyter J, Vaidyanathan K, Gardner T, Toriyama M, Marcotte EM, Roberson EC, Jackson PK, Reiter JF, Tizzano EF, Wallingford JB
bioRxiv : the preprint server for biology 2024 Sep 26;

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Prophylactic Effects of Betaine on Depression and Anxiety Behaviors in Mice with Dextran Sulfate Sodium-Induced Colitis.

Liu W, Zhong X, Yi Y, Xie L, Zhou W, Cao W, Chen L
Journal of agricultural and food chemistry 2024 Sep 25;72(38):21041-21051

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Alterations in anterior lens capsule structure and LTBP-2 expression in primary angle-closure glaucoma.

Tian X, Yuan L, Li L, Yuan X
BMJ open ophthalmology 2024 Sep 24;9(1)

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Schisandrin B attenuates bleomycin-induced pulmonary fibrosis in mice through AKT-mTOR pathway.

Yang J, Zhou D, Hu J, Yang DH, Cai Y, Lu Q
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG 2024 Sep 24;41(3):e2024034

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MCPIP1 Elicits a Therapeutic Effect on Cervical Cancer by Facilitating XIAP mRNA Decay via Its Endoribonuclease Activity.

Luo J, He L, Guo Y, Wang J, Liu H, Li Z
International journal of molecular sciences 2024 Sep 24;25(19)

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Knockdown of IGF2BP3 Down-Regulates PDCD4 Levels to Attenuate Hypoxic-Ischemic Brain Damage.

Chen Y, Fang X, Liu H, Fan Q
Frontiers in bioscience (Landmark edition) 2024 Sep 23;29(9):329

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Targeting ALDOA to modulate tumorigenesis and energy metabolism in retinoblastoma.

Wang Y, Tang J, Liu Y, Zhang Z, Zhang H, Ma Y, Wang X, Ai S, Mao Y, Zhang P, Chen S, Li J, Gao Y, Cheng C, Li C, Su S, Lu R
iScience 2024 Sep 20;27(9):110725

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METTL16-SENP3-LTF axis confers ferroptosis resistance and facilitates tumorigenesis in hepatocellular carcinoma.

Wang J, Xiu M, Wang J, Gao Y, Li Y
Journal of hematology & oncology 2024 Sep 2;17(1):78

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Combination of arsenic trioxide and apatinib synergistically inhibits small cell lung cancer by down-regulating VEGFR2/mTOR and Akt/c-Myc signaling pathway via GRB10.

Yu Y, Shang Y, Shi S, He Y, Shi W, Wang M, Wang Q, Xu D, Shi C, Chen H
Hereditas 2024 Sep 2;161(1):29

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Global remodeling of ADP-ribosylation by PARP1 suppresses influenza A virus infection.

Zhang Z, Uribe I, Davis KA, McPherson RL, Larson GP, Badiee M, Tran V, Ledwith MP, Feltman E, Yú S, Caì Y, Chang CY, Yang X, Ma Z, Chang P, Kuhn JH, Leung AKL, Mehle A
bioRxiv : the preprint server for biology 2024 Sep 19;

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Epicatechin and β-Glucan from Whole Highland Barley Grain Synergistic Benefit on Attenuating Hyperglycemia via Improving Hepatic Glucose Metabolism in Diabetic C57BL/6J Mice.

Liu Z, Zhang Z, Tang R, Liu J, Yang Y
Journal of agricultural and food chemistry 2024 Sep 18;72(37):20458-20469

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DNA-templated spatially controlled proteolysis targeting chimeras for CyclinD1-CDK4/6 complex protein degradation.

Zheng R, Prasad A, Satyabola D, Xu Y, Yan H
bioRxiv : the preprint server for biology 2024 Sep 18;

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VP3 protein of Senecavirus A promotes viral IRES-driven translation and attenuates innate immunity by specifically relocalizing hnRNPA2B1.

Li L, Li X, Zhong H, Li M, Wan B, He W, Zhang Y, Du Y, Chen D, Zhang W, Ji P, Jiang D, Han S
Journal of virology 2024 Sep 17;98(9):e0122724

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The 5'UTR of porcine reproductive and respiratory syndrome virus strain JXwn06 harbors a uORF that regulates cellular inflammation.

Liu T, Shao Q, Cui Z, Qing P, Gao P, Zhang Y, Zhou L, Ge X, Guo X, Han J, Yang H
Journal of virology 2024 Sep 17;98(9):e0113224

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Coxsackievirus group B3 regulates ASS1-mediated metabolic reprogramming and promotes macrophage inflammatory polarization in viral myocarditis.

Liu Q, Shang Y, Tao Z, Li X, Shen L, Zhang H, Liu Z, Rao Z, Yu X, Cao Y, Zeng L, Huang X
Journal of virology 2024 Sep 17;98(9):e0080524

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Targeting NAT10 inhibits osteosarcoma progression via ATF4/ASNS-mediated asparagine biosynthesis.

Zou Y, Guo S, Wen L, Lv D, Tu J, Liao Y, Chen W, Chen Z, Li H, Chen J, Shen J, Xie X
Cell reports. Medicine 2024 Sep 17;5(9):101728

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Engineering Biodegradable Hollow Silica/Iron Composite Nanozymes for Breast Tumor Treatment through Activation of the "Ferroptosis Storm".

Xue P, Zhuang H, Shao S, Bai T, Zeng X, Yan S
ACS nano 2024 Sep 17;18(37):25795-25812

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Analysis of vaginal flora diversity and study on the role of Porphyromonas asaccharolytica in promoting IL-1β in regulating cervical cancer.

Bai B, Tuerxun G, Tuerdi A, Maimaiti R, Sun Y, Abudukerimu A
Scientific reports 2024 Sep 17;14(1):21731

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Novel Dual PPAR δ/γ Partial Agonist Induces Hepatic Lipid Accumulation through Direct Binding and Inhibition of AKT1 Phosphorylation, Mediating CD36 Upregulation.

Cai X, Zhang Q, Wang J, Miao Y, Sun Y, Xia Z, Zhang L, Yu Q, Jiang Z
Chemical research in toxicology 2024 Sep 16;37(9):1574-1587

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Blueberry extract attenuates DSS-induced inflammatory bowel disease in mice through inhibiting ER stress-mediated colonic apoptosis in mice.

Wang J, Wang XY, Yuan ZY, Wang XH, Guan YY, Zhu JX, Huang WF, Liu Q, Xu GH, Yi LT
Food & function 2024 Sep 16;15(18):9541-9551

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Procyanidin B1 and p-coumaric acid from whole highland barley ameliorated HFD-induced impaired glucose tolerance via small intestinal barrier and hepatic glucose metabolism.

Liu Z, Yang Y, Xu Y, Zhang Z, Tang R, Liu J, Jiang H, Zhao R
Food & function 2024 Sep 16;15(18):9272-9283

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Tanreqing injection inhibits influenza virus replication by promoting the fusion of autophagosomes with lysosomes: An integrated pharmacological study.

Guo R, Liu H, Su R, Mao Q, Zhao M, Zhang H, Mu J, Zhao N, Wang Y, Hao Y
Journal of ethnopharmacology 2024 Sep 15;331:118159

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Proteomic characterization of the medial prefrontal cortex in chronic restraint stress mice.

Fu Y, Gu Z, Cao H, Zuo C, Huang Y, Song Y, Miao J, Jiang Y, Wang F
Journal of proteomics 2024 Sep 15;307:105278

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Follicular fluid HD-sevs-mir-128-3p is a key molecule in regulating bovine granulosa cells autophagy.

Ying W, Yunqi Z, Deji L, Jian K, Fusheng Q
Theriogenology 2024 Sep 15;226:263-276

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Sirt2 Regulates Liver Metabolism in a Sex-Specific Manner.

Schmidt AV, Bharathi SS, Solo KJ, Bons J, Rose JP, Schilling B, Goetzman ES
Biomolecules 2024 Sep 15;14(9)

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Hsa_circ_0000825 promotes the progression of laryngeal squamous cell carcinoma by sponging miR-766 and interacting with ELAVL1.

Yu M, Cao H, Yang J, Liu T, Wang B
Heliyon 2024 Sep 15;10(17):e37264

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PMMA-induced biofilm promotes Schwann cells migration and proliferation mediated by EGF/Tnc/FN1 to improve sciatic nerve defect.

Wang J, Hu Y, Xue Y, Wang K, Mao D, Pan XY, Rui Y
Heliyon 2024 Sep 15;10(17):e37231

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Oral administration of tea-derived exosome-like nanoparticles protects epithelial and immune barrier of intestine from psychological stress.

Gong Q, Sun Y, Liu L, Pu C, Guo Y
Heliyon 2024 Sep 15;10(17):e36812

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Mechanisms of Yiai Fuzheng formula in the treatment of triple-negative breast cancer based on UPLC-Q-Orbitrap-HRMS, network pharmacology, and experimental validation.

Li R, Ke H, Liu P, Yang Q, Li Y, Ke L, Wang X, Wu C, Zhang Y
Heliyon 2024 Sep 15;10(17):e36579

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Time-restricted feeding relieves high temperature-induced impairment on meat quality by activating the Nrf2/HO-1 pathway, modification of muscle fiber composition, and enriching the polyunsaturated fatty acids in pigs.

Li Z, Wang Y, Yuan P, Zhu Y, Hu P, Song T, Liu R, Liu HY, Cai D
Stress biology 2024 Sep 14;4(1):39

---

ONC212, alone or in synergistic conjunction with Navitoclax (ABT-263), promotes cancer cell apoptosis via unconventional mitochondrial-independent caspase-3 activation.

Basu V, Shabnam, Murghai Y, Ali M, Sahu S, Verma BK, Seervi M
Cell communication and signaling : CCS 2024 Sep 13;22(1):441

---

Chitosan-Modified AgNPs Efficiently Inhibit Swine Coronavirus-Induced Host Cell Infections via Targeting the Spike Protein.

Wang D, Yin C, Bai Y, Zhou M, Wang N, Tong C, Yang Y, Liu B
Biomolecules 2024 Sep 13;14(9)

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The NRF2-CARM1 axis links glucose sensing to transcriptional and epigenetic regulation of the pentose phosphate pathway in gastric cancer.

Ping M, Li G, Li Q, Fang Y, Fan T, Wu J, Zhang R, Zhang L, Shen B, Guo J
Cell death & disease 2024 Sep 12;15(9):670

---

Protein disulfide isomerase PDI8 is indispensable for parasite growth and associated with secretory protein processing in Toxoplasma gondii.

Wang C, Sun P, Jia Y, Tang X, Liu X, Suo X, Peng H
mBio 2024 Sep 11;15(9):e0205124

---

ASB3 expression aggravates inflammatory bowel disease by targeting TRAF6 protein stability and affecting the intestinal microbiota.

Cheng M, Xu B, Sun Y, Wang J, Lu Y, Shi C, Pan T, Zhao W, Li X, Song X, Wang J, Wang N, Yang W, Jiang Y, Huang H, Yang G, Zeng Y, Yang D, Wang C, Cao X
mBio 2024 Sep 11;15(9):e0204324

---

Hypothalamic SLC7A14 accounts for aging-reduced lipolysis in white adipose tissue of male mice.

Jiang X, Liu K, Luo P, Li Z, Xiao F, Jiang H, Wu S, Tang M, Yuan F, Li X, Shu Y, Peng B, Chen S, Ni S, Guo F
Nature communications 2024 Sep 11;15(1):7948

---

Novel gene therapy for drug-resistant melanoma: Synergistic combination of PTEN plasmid and BRD4 PROTAC-loaded lipid nanocarriers.

Saraswat A, Vemana HP, Dukhande V, Patel K
Molecular therapy. Nucleic acids 2024 Sep 10;35(3):102292

---

Dendritic Cells Pulsed with HAM/TSP Exosomes Sensitize CD4 T Cells to Enhance HTLV-1 Infection, Induce Helper T-Cell Polarization, and Decrease Cytotoxic T-Cell Response.

Joseph J, Premeaux TA, Tandon R, Murphy EL, Bruhn R, Nicot C, Herrera BB, Lemenze A, Alatrash R, Baffour Tonto P, Ndhlovu LC, Jain P
Viruses 2024 Sep 10;16(9)

---

Diosgenin attenuates metabolic-associated fatty liver disease through the hepatic NLRP3 inflammasome-dependent signaling pathway.

Yu W, Yin G, Chen S, Zhang X, Meng D, Wang L, Liu H, Jiang W, Sun Y, Zhang F
International immunopharmacology 2024 Sep 10;138:112581

---

Harmine inhibits pulmonary fibrosis through regulating DNA damage repair-related genes and activation of TP53-Gadd45α pathway.

Gong Y, Wang J, Pan M, Zhao Y, Zhang H, Zhang F, Liu J, Yang J, Hu J
International immunopharmacology 2024 Sep 10;138:112542

---

Fatty acid synthesis is indispensable for Kupffer cells to eliminate bacteria in ALD progression.

Xie L, Wu B, Fan Y, Tao Y, Jiang X, Li Q, Zhu H, Wang H, Hu C
Hepatology communications 2024 Sep 1;8(9)

---

Mfsd2a regulates the blood-labyrinth-barrier formation and function through tight junctions and transcytosis.

Xu X, Xu K, Chen F, Yu D, Wang X
Hearing research 2024 Sep 1;450:109048

---

Caspase-8 promotes NLRP3 inflammasome activation mediates eye development defects in zebrafish larvae exposed to perfulorooctane sulfonate (PFOS).

Wu LY, Zhang JL, Zeeshan M, Zhou Y, Zhang YT, He WT, Jin N, Dai Y, Chi W, Ou Z, Dong GH, Lin LZ
Environmental pollution (Barking, Essex : 1987) 2024 Sep 1;356:124252

---

Intervention of epithelial mesenchymal transition against colon cancer cell growth and metastasis based on SOX21/POU4F2/Hedgehog signaling axis.

Cao Q, Gao Y, Zhou C, Yan Y, Yu J, Wang P, Zhang B, Sun L
Life sciences 2024 Sep 1;352:122905

---

Lactate promotes fatty acid oxidation by the tricarboxylic acid cycle and mitochondrial respiration in muscles of obese mice.

Park SY, Jung SR, Kim JY, Kim YW, Sung HK, Park SY, Doh KO, Koh JH
American journal of physiology. Cell physiology 2024 Sep 1;327(3):C619-C633

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Mycobacterium tuberculosis Utilizes Serine/Threonine Kinase PknF to Evade NLRP3 Inflammasome-driven Caspase-1 and RIPK3/Caspase-8 Activation in Murine Dendritic Cells.

Rastogi S, Ganesh A, Briken V
Journal of immunology (Baltimore, Md. : 1950) 2024 Sep 1;213(5):690-699

---

Chemotactic recruitment of genetically engineered cell membrane-camouflaged metal-organic framework nanoparticles for ischemic osteonecrosis treatment.

Jiang H, Xia W, Xia T, Jiang L, Yu J, Zhu X, Lin C, Lou C, Wang W, Chai Y, Wan R, Wang J, Xue X, Pan X
Acta biomaterialia 2024 Sep 1;185:410-428

---

Berberine as a potential enhancer for 5-ALA-mediated fluorescence in glioblastoma: increasing detectability of infiltrating glioma stem cells to optimize 5-ALA-guided surgery.

Ohtsuka Y, Suehiro S, Inoue A, Ohnishi T, Nishikawa M, Yamashita D, Yano H, Choudhury ME, Ozaki S, Sampetrean O, Saya H, Watanabe H, Tanaka J, Kunieda T
Journal of neurosurgery 2024 Sep 1;141(3):653-663

---

Design, synthesis, and biological evaluation of novel 1-amido-2-one-4-thio-deoxypyranose as potential antitumor agents for multiple myeloma.

Li X, Zhang H, Dong S, Gao X, Sun H, Zhou Z, Hu K, Guo S, Zhang Q, Guo Z, Jacob Bunu S, Zhu J, Li B, Zhang Y, Shen J, Akber Aisa H, Xu Z, Cai H, Shi J, Zhu W
Bioorganic & medicinal chemistry 2024 Sep 1;111:117843

---

Central role of Sigma-1 receptor in ochratoxin A-induced ferroptosis.

Chen W, Han L, Yang R, Wang H, Yao S, Deng H, Liu S, Zhou Y, Shen XL
Archives of toxicology 2024 Oct;98(10):3323-3336

---

SIRT1 Ameliorates Lamin A/C Deficiency-Induced Cardiac Dysfunction by Promoting Mitochondrial Bioenergetics.

Du Z, Zhou Y, Li Q, Xie Y, Zhu T, Qiao J, Zhang R, Bao Y, Wang L, Xie Y, Quan J, Lin M, Zhang N, Jin Q, Liang W, Wu L, Yin T, Xie Y
JACC. Basic to translational science 2024 Oct;9(10):1211-1230

---

AQP4 Endocytosis-Lysosome Degradation Mediated by MMP-9/β-DG Involved in Diabetes Cognitive Impairment.

Yuan Y, Peng W, Lei J, Zhao Y, Zhao B, Li Y, Wang J, Qu Q
Molecular neurobiology 2024 Oct;61(10):8438-8453

---

Influenza A Virus PB1-F2 Induces Affective Disorder by Interfering Synaptic Plasticity in Hippocampal Dentate Gyrus.

Wang S, Zhang H, Liu R, Han P, Yang Q, Cheng C, Chen Y, Rong Z, Su C, Li F, Wei G, Zhao M, Yang L
Molecular neurobiology 2024 Oct;61(10):8293-8306

---

SFRP1 reduces neutrophil infiltration and inhibits the Wnt/β-catenin pathway to alleviate oral submucous fibrosis.

Zhou R, Yin L, Zhang X, Zhu K
In vitro cellular & developmental biology. Animal 2024 Oct;60(9):1034-1045

---

Inflammatory microenvironment of moderate pulpitis enhances the osteo-/odontogenic potential of dental pulp stem cells by autophagy.

Yu S, Liu XM, Liu Y, Tang L, Lei S, Geng C, Yuan Z, Chen X
International endodontic journal 2024 Oct;57(10):1465-1477

---

WTAP promotes fibroblast-like synoviocyte pyroptosis in Rheumatoid arthritis by upregulating N6-methyladenosine modification of NLRP3.

Liu X, Xia Z, Liu L, Ren D
Journal of bioenergetics and biomembranes 2024 Oct;56(5):563-571

---

Unveiling the role of RhoA and ferroptosis in vascular permeability: Implications for osteoarthritis.

He X, Tian K, Lin X, Chen X, Su Y, Lu Z, Chen Z, Zhang L, Li P, Ma L, Feng G, Zhao X, Lan Z, Zhang C, Xue D, Jin Q
International journal of molecular medicine 2024 Oct;54(4)

---

Zinc finger protein 180 induces an apoptotic phenotype by activating METTL14 transcriptional activity in colorectal cancer.

Xu L, Chen XJ, Yan Q, Lei XT, Liu HL, Xu JP, Shang WT, Huang JL, Chen ZT, Tan XL, Lin HJ, Fu XH, Zheng LS, Lan P, Huang Y
Oncology reports 2024 Oct;52(4)

---

Sunitinib alleviates hepatic ischemia reperfusion injury by inhibiting the JAK2/STAT pathway and promoting the M2 polarization of macrophages.

Li M, Tan J, Zhang R, Gong X, Xie J, Liu C, Wu C, Li X
Immunopharmacology and immunotoxicology 2024 Oct;46(5):672-684

---

The tumor suppressor Parkin exerts anticancer effects through regulating mitochondrial GAPDH activity.

Sun X, Ye G, Li J, Yuan L, Bai G, Xu YJ, Zhang J
Oncogene 2024 Oct;43(44):3215-3226

---

USP33 facilitates the ovarian cancer progression via deubiquitinating and stabilizing CBX2.

Chen J, Shan W, Jia Q, Chen Y, Jiang W, Tian Y, Huang X, Li X, Wang Z, Xia B
Oncogene 2024 Oct;43(43):3170-3183

---

RBM12 drives PD-L1-mediated immune evasion in hepatocellular carcinoma by increasing JAK1 mRNA translation.

Han H, Shi Q, Zhang Y, Ding M, He X, Liu C, Zhao D, Wang Y, Du Y, Zhu Y, Yuan Y, Wang S, Guo H, Wang Q
Oncogene 2024 Oct;43(41):3062-3077

---

Electroacupuncture ameliorates senile osteoporosis by promoting bone remodeling and regulating autophagy.

Liu J, Zhou J, Wang J, Huang X, Qu M, Liao Y, Sun G, Zhong P, Tan J, Sun Z
Acupuncture in medicine : journal of the British Medical Acupuncture Society 2024 Oct;42(5):260-267

---

Glycyrrhizin Protects Submandibular Gland Against Radiation Damage by Enhancing Antioxidant Defense and Preserving Mitochondrial Homeostasis.

Zhou XR, Wang XY, Sun YM, Zhang C, Liu KJ, Zhang FY, Xiang B
Antioxidants & redox signaling 2024 Oct;41(10-12):723-743

---

Dexmedetomidine attenuates ferroptosis by Keap1-Nrf2/HO-1 pathway in LPS-induced acute kidney injury.

Luo RR, Yang J, Sun YL, Zhou BY, Zhou SX, Zhang GX, Yang AX
Naunyn-Schmiedeberg's archives of pharmacology 2024 Oct;397(10):7785-7796

---

PTPN7 mediates macrophage-polarization and determines immunotherapy in gliomas: A single-cell sequencing analysis.

Ji X, Cheng J, Su J, Wen R, Zhang Q, Liu G, Peng Y, Mao J
Environmental toxicology 2024 Oct;39(10):4562-4580

---

Neuronal HIPK2-HDAC3 axis regulates mitochondrial fragmentation to participate in stroke injury and post-stroke anxiety like behavior.

Yang M, Zhu H, Peng L, Yin T, Sun S, Du Y, Li J, Liu J, Wang S
Experimental neurology 2024 Oct;380:114906

---

Helicobacter pylori induce circ_0046854 to regulate microRNA-511-3p/CSF1 axis and enhance the resistance of gastric cancer to cisplatin.

Ma J, Zhang S, Gong Y, Wang C
Journal of biochemical and molecular toxicology 2024 Oct;38(10):e23831

---

Identification of KIFC1 as a putative vulnerability in lung cancers with centrosome amplification.

Zhang C, Wu BZ, Di Ciano-Oliveira C, Wu YF, Khavkine Binstock SS, Soria-Bretones I, Pham NA, Elia AJ, Chari R, Lam WL, Bray MR, Mak TW, Tsao MS, Cescon DW, Thu KL
Cancer gene therapy 2024 Oct;31(10):1559-1570

---

UGT1A7 altered HER2-positive breast cancer response to trastuzumab by affecting epithelial-to-mesenchymal transition: A potential biomarker to identify patients resistant to trastuzumab treatment.

Wang C, Bai C, Zhang Z, Zhou H, Gao H, Wang S, Yuan Y
Cancer gene therapy 2024 Oct;31(10):1525-1535

---

Nucleolin malonylation as a nuclear-cytosol signal exchange mechanism to drive cell proliferation in Hepatocarcinoma by enhancing AKT translation.

Sun L, Meng H, Liu T, Zhao Q, Xia M, Zhao Z, Qian Y, Cui H, Zhong X, Chai K, Tian Y, Sun Y, Zhu B, Di J, Shui G, Zhang L, Zheng J, Guo S, Liu Y
The Journal of biological chemistry 2024 Oct;300(10):107785

---

Circular RNA CircACAP2 regulates temporomandibular joint osteoarthritis via miR-21-5p/PLAG1 axis.

Chen H, Qu Z, Shi T, Zhao H, Huang S, Ma C
Oral diseases 2024 Oct;30(7):4440-4453

---

Inhibiting endoplasmic reticulum stress alleviates perioperative neurocognitive disorders by reducing neuroinflammation mediated by NLRP3 inflammasome activation.

Meng F, Song J, Huang X, Zhang M, Sun X, Jing Q, Cao S, Xie Z, Liu Q, Zhang H, Li C
CNS neuroscience & therapeutics 2024 Oct;30(10):e70049

---

GLS2 reduces the occurrence of epilepsy by affecting mitophagy function in mouse hippocampal neurons.

Gao Y, Ma L, Yuan J, Huang Y, Ban Y, Zhang P, Tan D, Liang M, Li Z, Gong C, Xu T, Yang X, Chen Y
CNS neuroscience & therapeutics 2024 Oct;30(10):e70036

---

SEH1L siliencing induces ferroptosis and suppresses hepatocellular carcinoma progression via ATF3/HMOX1/GPX4 axis.

Feng Z, Cao K, Sun H, Liu X
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1723-1737

---

Bacillus paralicheniformis, an acetate-producing probiotic, alleviates ulcerative colitis via protecting the intestinal barrier and regulating the NLRP3 inflammasome.

Dai N, Yang X, Pan P, Zhang G, Sheng K, Wang J, Liang X, Wang Y
Microbiological research 2024 Oct;287:127856

---

Therapeutic framework nucleic acid complexes targeting oxidative stress and pyroptosis for the treatment of osteoarthritis.

Li J, Li Y, Shang X, Xu S, Zhang Z, Xu S, Wang X, Shen M
Materials today. Bio 2024 Oct;28:101202

---

A novel angiotensin I-converting enzyme inhibitory peptide APPLRP from Grifola frondosa ameliorated the Ang II-induced vascular modeling in zebrafish model by mediating smooth muscle cells.

Song T, Zhang T, Cai Q, Ding YY, Gu Z
International journal of biological macromolecules 2024 Oct;278(Pt 4):134998

---

Epicatechin and β-glucan from whole highland barley grain ameliorates hyperlipidemia associated with attenuating intestinal barrier dysfunction and modulating gut microbiota in high-fat-diet-fed mice.

Liu Z, Tang R, Liu J, Zhang Z, Li Y, Zhao R
International journal of biological macromolecules 2024 Oct;278(Pt 3):134917

---

Prebiotic stachyose inhibits PRDX5 activity and castration-resistant prostate cancer development.

Wang R, Pan Y, Zhang L, Wang J, Ni J, Ding Y, Wang S, Yin J, Ding L, Ran X, Fan S, Sun Q, Tan SY, Koeffler HP, Li J, Mi Y, Chen YQ
International journal of biological macromolecules 2024 Oct;278(Pt 3):134844

---

African swine fever virus pCP312R interacts with host RPS27A to shut off host protein translation and promotes viral replication.

Hagoss YT, Shen D, Wang W, Zhang Z, Li F, Sun E, Zhu Y, Ge J, Guo Y, Bu Z, Zhao D
International journal of biological macromolecules 2024 Oct;277(Pt 3):134213

---

Xylooligosaccharides alleviate the carbohydrate-enriched diet-induced intestinal barrier dysfunction in carp Megalobrama amblycephala by promoting intestinal development, immunity and gut microbiota.

Chen WL, Dong YZ, Zhang L, Liu ZS, He CF, Liu WB, Li XF
International journal of biological macromolecules 2024 Oct;277(Pt 2):134346

---

Lycium ruthenicum Murray derived exosome-like nanovesicles inhibit Aβ-induced apoptosis in PC12 cells via MAPK and PI3K/AKT signaling pathways.

Zhang Y, Zhang X, Kai T, Zhang L, Li A
International journal of biological macromolecules 2024 Oct;277(Pt 2):134309

---

S100A9-TLR4 axis aggravates dry eye through the blockage of autophagy.

Liang L, Yang X, Zeng H, Liao K, Zhang R, Wang B, Yuan J
Experimental eye research 2024 Oct;247:110052

---

Panobinostat sensitizes AraC-resistant AML cells to the combination of azacitidine and venetoclax.

Zhao J, Wu S, Wang D, Edwards H, Thibodeau J, Kim S, Stemmer P, Wang G, Jin J, Savasan S, Taub JW, Ge Y
Biochemical pharmacology 2024 Oct;228:116065

---

Rapamycin Attenuates H(2)O(2)-Induced Oxidative Stress-Related Senescence in Human Skin Fibroblasts.

Tang Y, Yang S, Qiu Z, Guan L, Wang Y, Li G, Tu Y, Guo L
Tissue engineering and regenerative medicine 2024 Oct;21(7):1049-1059

---

Ginkgo Biloba Extract Can Antagonize Subchronic Arsenite Exposure-Induced Hepatocyte Senescence by Inhibiting Oxidative Damage and Inflammation in Rats.

Chen X, Wu F, Chen C, Ren Q, Zhang A
Biological trace element research 2024 Oct;202(10):4596-4604

---

Lactate Contributes to Remote Ischemic Preconditioning-Mediated Protection Against Myocardial Ischemia Reperfusion Injury by Facilitating Autophagy via the AMP-Activated Protein Kinase-Mammalian Target of Rapamycin-Transcription Factor EB-Connexin 43 Axis.

Yang ZJ, Zhang WF, Jin QQ, Wu ZR, Du YY, Shi H, Qu ZS, Han XJ, Jiang LP
The American journal of pathology 2024 Oct;194(10):1857-1878

---

Procyanidine alleviates bisphenol A-induced apoptosis in TM3 cells via the Nrf2 signaling pathway.

Pan F, Yang W, Zhao T, Liu K, Zhao S, Zhao L
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Oct;192:114908

---

Capturing acyl-enzyme intermediates with genetically encoded 2,3-diaminopropionic acid for hydrolase substrate identification.

Luo J, Yu Y, Wang K, He S, Wang L, Liang F, Chin JW, Tang S
Nature protocols 2024 Oct;19(10):2967-2999

---

Adipocyte-conditioned medium induces tamoxifen resistance by activating PI3K/Akt/mTOR pathway in estrogen receptor-positive breast cancer cells.

Nakatsuji M, Fujimori K
Biochimica et biophysica acta. Molecular cell research 2024 Oct;1871(7):119821

---

BCL6 overexpression in CD4(+) T cells induces Tfh-like transdifferentiation and enhances antitumor efficiency of CAR-T therapy in pancreatic cancer.

Lin X, Dai Z, Tasiheng Y, Zhang R, Wang R, Dong J, Chen Y, Ma M, Zou X, Yan Y, Wang X, Yu X, Cheng H, Liu C
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167346

---

LncRNA H19/miR-107 regulates endothelial progenitor cell pyroptosis and promotes flow recovery of lower extremity ischemia through targeting FADD.

Huang L, Ye Y, Sun Y, Zhou Z, Deng T, Liu Y, Wu R, Wang K, Yao C
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167323

---

Integrator complex subunit 6 promotes hepatocellular steatosis via β-catenin-PPARγ axis.

Shiozaki M, Kanno K, Yonezawa S, Otani Y, Shigenobu Y, Haratake D, Murakami E, Oka S, Ito M
Biochimica et biophysica acta. Molecular and cell biology of lipids 2024 Oct;1869(7):159532

---

Targeting SMYD2 promotes ferroptosis and impacts the progression of pancreatic cancer through the c-Myc/NCOA4 axis-mediated ferritinophagy.

Tan J, Liao S, Yuan B, Liu X, Yu W, Zhan H, Jiang Y, Liu Y
Biochimica et biophysica acta. General subjects 2024 Oct;1868(10):130683

---

Corilagin alleviates ferroptosis in diabetic retinopathy by activating the Nrf2 signaling pathway.

Shi W, Dong Y, Liu S, Li F, Zhu C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Oct;179:117409

---

Preparation of photo-controlled release ROS-responsive Ce6/elemene co-loaded liposomes and study on the effect on enhancing apoptosis of NMIBC.

Zhang X, Mei W, Guo D, Sun J, Shi Y, Zhang X, Zou J, Cheng J, Luan F, Zhai B, Tian H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Oct;179:117398

---

Gentiana decoction inhibits liver fibrosis and the activation of hepatic stellate cells via upregulating the expression of Parkin.

Deng J, Long J, Yang Y, Yang F, Wei Y
Fitoterapia 2024 Oct;178:106170

---

ITCH inhibits alkaliptosis in human pancreatic cancer cells through YAP1-dependent SLC16A1 activation.

Cai X, Chen F, Tang H, Chao D, Kang R, Tang D, Liu J
The international journal of biochemistry & cell biology 2024 Oct;175:106646

---

Multiomics reveals microbial metabolites as key actors in intestinal fibrosis in Crohn's disease.

Li X, Hu S, Shen X, Zhang R, Liu C, Xiao L, Lin J, Huang L, He W, Wang X, Huang L, Zheng Q, Wu L, Sun C, Peng Z, Chen M, Li Z, Feng R, Zhu Y, Wang Y, Li Z, Mao R, Feng ST
EMBO molecular medicine 2024 Oct;16(10):2427-2449

---

Mitochondrial dysfunction and oxidative stress in selective fetal growth restriction.

Hu Y, Lin Y, Yang J, Wang S, Gao L, Bi Y, Wang Y
Placenta 2024 Oct;156:46-54

---

Identification of TACSTD2 as novel therapeutic targets for cisplatin-induced acute kidney injury by multi-omics data integration.

Deng Z, Dong Z, Wang Y, Dai Y, Liu J, Deng F
Human genetics 2024 Oct;143(9-10):1061-1080

---

Jiawei Buzhong Yiqi Decoction attenuates polycystic ovary syndrome through regulating kisspeptin-GPR54-AKT-SHBG system.

Hu R, Geng Y, Huang Y, Liu Z, Li F, Song K, Ma W, Dong H, Zhang M, Lei T, Song Y, Zhang Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Oct;133:155931

---

Schisandra chinensis lignans regulate and cooperate with endogenous cannabinoid systems to ameliorate intestinal barrier injury associated with depression.

Wang J, Zheng A, Lin F, Zhang X, Shi K, Yan T, Jia Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Oct;133:155929

---

Asiaticoside modulates human NK cell functional fate by mediating metabolic flexibility in the tumor microenvironment.

Guo Y, Xu J, Jia Y, Tian Y, Zhang Y, Zhang J, Wang Y, Chen L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Oct;133:155921

---

Neutrophil-Mediated Nanozyme Delivery System for Acute Kidney Injury Therapy.

Yang Y, Du J, Gan J, Song X, Shu J, An C, Lu L, Wei H, Che J, Zhao X
Advanced healthcare materials 2024 Oct;13(26):e2401198

---

The expression and role of SUZ12 in lung adenocarcinoma.

Hu X, Hu C, Zhong P
Cancer medicine 2024 Oct;13(19):e70190

---

Methyltransferase-Like 3-Mediated N6-Methyladenosine RNA Methylation Regulates Hypoxia-Induced Pulmonary Arterial Smooth Muscle Cell Pyroptosis by Targeting PTEN.

Jiang Y, Liu H, Shi R, Hao Y, Zhang J, Xin W, Li Y, Ma C, Zheng X, Zhang L, Zhao X, Zhu D
Journal of the American Heart Association 2024 Oct;13(19):e034470

---

ESRRA modulation by empagliflozin mitigates diabetic tubular injury via mitochondrial restoration.

Yang K, Liang W, Hu H, Zhang Z, Hao Y, Song Z, Yang L, Hu J, Chen Z, Ding G
Cellular signalling 2024 Oct;122:111308

---

Oleanolic acid attenuates obesity through modulating the lipid metabolism in high-fat diet-fed mice.

Zhang G, Zhang H, Dong R, Zhao H, Li J, Yue W, Ma Z
Food science & nutrition 2024 Oct;12(10):8243-8254

---

N-acetylgalactosaminyltransferase GALNT6 is a potential therapeutic target of clear cell renal cell carcinoma progression.

Sun L, Li Z, Shu P, Lu M
Cancer science 2024 Oct;115(10):3320-3332

---

Platelet-Derived Growth Factor C Facilitates Malignant Behavior of Pancreatic Ductal Adenocarcinoma by Regulating SREBP1 Mediated Lipid Metabolism.

Shi YH, Liu ZD, Ma MJ, Zhao GY, Zhu YQ, Wang JQ, Yu YY, Huang XT, Ye JY, Li FX, Wang XY, Xu QC, Yin XY
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Oct;11(40):e2407069

---

TMEM16F Expressed in Kupffer Cells Regulates Liver Inflammation and Metabolism to Protect Against Listeria Monocytogenes.

Tang J, Song H, Li S, Lam SM, Ping J, Yang M, Li N, Chang T, Yu Z, Liu W, Lu Y, Zhu M, Tang Z, Liu Z, Guo YR, Shui G, Veillette A, Zeng Z, Wu N
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Oct;11(39):e2402693

---

Irisin-Encapsulated Mitochondria-Targeted Biomimetic Nanotherapeutics for Alleviating Acute Kidney Injury.

Zhang X, Liang L, Wang F, Jose PA, Chen K, Zeng C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Oct;11(38):e2402805

---

Effective Prevention and Treatment of Acute Leukemias in Mice by Activation of Thermogenic Adipose Tissues.

Chen R, Cheng T, Xie S, Sun X, Chen M, Zhao S, Ruan Q, Ni X, Rao M, Quan X, Chen K, Zhang S, Cheng T, Xu Y, Chen Y, Yang Y, Cao Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Oct;11(38):e2402332

---

Poxin-deficient poxviruses are sensed by cGAS prior to genome replication.

Lant S, Hood AJM, Holley JA, Ellis A, Eke L, Sumner RP, Ulaeto DO, Maluquer de Motes C
The Journal of general virology 2024 Oct;105(10)

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Orally Administered Ginkgolide C Alleviates MPTP-Induced Neurodegeneration by Suppressing Neuroinflammation and Oxidative Stress through Microbiota-Gut-Brain Axis in Mice.

Gao X, Fu S, Wen J, Yan A, Yang S, Zhang Y, Liu D, He D
Journal of agricultural and food chemistry 2024 Oct 9;72(40):22115-22131

---

Silencing endomucin in bone marrow sinusoids improves hematopoietic stem and progenitor cell homing during transplantation.

Li Y, Ren M, Li H, Zhang Z, Yuan K, Huang Y, Yuan S, Ju W, He Y, Xu K, Zeng L
Stem cells (Dayton, Ohio) 2024 Oct 9;42(10):889-901

---

Interferon regulatory factor 7 alleviates the experimental colitis through enhancing IL-28A-mediated intestinal epithelial integrity.

Qing F, Tian H, Wang B, Xie B, Sui L, Xie X, He W, He T, Li Y, He L, Guo Q, Liu Z
Journal of translational medicine 2024 Oct 6;22(1):905

---

EPO modified MSCs protects SH-SY5Y cells against ischemia/hypoxia-induced apoptosis via REST-dependent epigenetic remodeling.

Jiang Y, Li R, Ban Y, Zhang W, Kong N, Tang J, Ma B, Shao Y, Jin R, Sun L, Yue H, Zhang H
Scientific reports 2024 Oct 6;14(1):23252

---

Vitamin D receptor attenuates carbon tetrachloride-induced liver fibrosis via downregulation of YAP.

Wang P, Li J, Ji M, Pan J, Cao Y, Kong Y, Zhu L, Li J, Li B, Chang L, Zhang Z
Journal of hazardous materials 2024 Oct 5;478:135480

---

Effects of WuHuTang on the function and autophagy of dendritic cells treated with exosomes induced by RSV.

Liu J, Yao B, Luo Y, Zhou Z, Ma X, Ding Y, Wang M
Journal of ethnopharmacology 2024 Oct 5;332:118397

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Untargeted serum and gastric metabolomics and network pharmacology analysis reveal the superior efficacy of zingiberis rhizoma recens-/euodiae fructus-processed Coptidis Rhizoma on gastric ulcer rats.

Zhang Z, Zheng Y, Zhang B, Wang R, Chen L, Wang Y, Feng W, Zheng X, Li K, Zhou N
Journal of ethnopharmacology 2024 Oct 5;332:118376

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MerTK(+) macrophages promote melanoma progression and immunotherapy resistance through AhR-ALKAL1 activation.

Wu N, Li J, Li L, Yang L, Dong L, Shen C, Sha S, Fu Y, Dong E, Zheng F, Tan Z, Tao J
Science advances 2024 Oct 4;10(40):eado8366

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TARDBP drives T-cell acute lymphoblastic leukemia progression by binding MDM2 mRNA, involving β-catenin pathway.

Mai Y, Jing Z, Sun P, Wang Y, Dong P, Liu J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Oct 31;38(20):e70110

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Ameliorating lipopolysaccharide induced acute lung injury with Lianhua Qingke: focus on pulmonary endothelial barrier protection.

Ma Y, Hou Y, Han Y, Liu Y, Han N, Yin Y, Wang X, Jin P, He Z, Sun J, Hao Y, Guo J, Wang T, Feng W, Qi H, Jia Z
Journal of thoracic disease 2024 Oct 31;16(10):6899-6917

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Flavopiridol induces cell cycle arrest and apoptosis by interfering with CDK1 signaling pathway in human ovarian granulosa cells.

Li XZ, Song W, Zhao ZH, Lu YH, Xu GL, Yang LJ, Yin S, Sun QY, Chen LN
Scientific reports 2024 Oct 31;14(1):26239

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ZC3HAV1 facilitates STING activation and enhances inflammation.

Qin D, Song H, Wang C, Ma X, Fu Y, Zhao C, Zhao W, Zhang L, Zhang W
Communications biology 2024 Oct 30;7(1):1418

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Inhibition of Glycolysis Alleviates Chronic Unpredictable Mild Stress Induced Neuroinflammation and Depression-like Behavior.

Liu B, Dong K, Chen X, Dong H, Zhao Y, Wang X, Sun Z, Xie F, Qian L
Brain sciences 2024 Oct 30;14(11)

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Neurons enhance blood-brain barrier function via upregulating claudin-5 and VE-cadherin expression due to glial cell line-derived neurotrophic factor secretion.

Yang L, Lin Z, Mu R, Wu W, Zhi H, Liu X, Yang H, Liu L
eLife 2024 Oct 30;13

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Identifying the signature of NAD+ metabolism-related genes for immunotherapy of gastric cancer.

Wen H, Mi Y, Li F, Xue X, Sun X, Zheng P, Liu S
Heliyon 2024 Oct 30;10(20):e38823

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A combined analysis of bulk RNA-seq and scRNA-seq was performed to investigate the molecular mechanisms associated with the occurrence of myocardial infarction.

Xie Z, Xie H, Xie C, Yang S, Feng Y, Su Z, Tang T, Zhang B, Yang J, Wang Y, Huang L, Zhu H, Cao J, Jiang R, Li T, Lu W
BMC genomics 2024 Oct 3;25(1):921

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FGF21 modulates immunometabolic homeostasis via the ALOX15/15-HETE axis in early liver graft injury.

Yang X, Chen H, Shen W, Chen Y, Lin Z, Zhuo J, Wang S, Yang M, Li H, He C, Zhang X, Hu Z, Lian Z, Yang M, Wang R, Li C, Pan B, Xu L, Chen J, Wei X, Wei Q, Xie H, Zheng S, Lu D, Xu X
Nature communications 2024 Oct 3;15(1):8578

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Aberrant cytoplasmic expression of UHRF1 restrains the MHC-I-mediated anti-tumor immune response.

Tan L, Yin T, Xiang H, Wang L, Mudgal P, Chen J, Ding Y, Wang G, Lim BJW, Huang Y, Huang D, Liang Y, Alexander PB, Xiang K, Wang E, Yan C, Ma Z, Tan M, Li QJ, Wang XF
Nature communications 2024 Oct 3;15(1):8569

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Integrated network pharmacology and pharmacological investigations to discover the active compounds of Toona sinensis pericarps against diabetic nephropathy.

Li H, Wang R, Chen Y, Zhao M, Lan S, Zhao C, Li X, Li W
Journal of ethnopharmacology 2024 Oct 28;333:118441

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Traditional medicine Xianglian pill suppresses high-fat diet-related colorectal cancer via inactivating TLR4/MyD88 by remodeling gut microbiota composition and bile acid metabolism.

Ye C, Wu C, Li Y, Chen C, Li X, Zhang J, Xu Z, Chen H, Guo Y
Journal of ethnopharmacology 2024 Oct 28;333:118411

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CHIP drives proteasomal degradation of NUR77 to alleviate oxidative stress and intrinsic apoptosis in cisplatin-induced nephropathy.

Zhang H, Deng Z, Wang Y, Zheng X, Zhou L, Yan S, Wang Y, Dai Y, Kanwar YS, Chen F, Deng F
Communications biology 2024 Oct 26;7(1):1403

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Apoptotic vesicles from macrophages exacerbate periodontal bone resorption in periodontitis via delivering miR-143-3p targeting Igfbp5.

Xiao J, Deng Y, Xie J, Liu H, Yang Q, Zhang Y, Huang X, Cao Z
Journal of nanobiotechnology 2024 Oct 26;22(1):658

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Regulation of hepatic inclusions and fibrinogen biogenesis by SEL1L-HRD1 ERAD.

Song Z, Thepsuwan P, Hur WS, Torres M, Wu SA, Wei X, Tushi NJ, Wei J, Ferraresso F, Paton AW, Paton JC, Zheng Z, Zhang K, Fang D, Kastrup CJ, Jaiman S, Flick MJ, Sun S
Nature communications 2024 Oct 26;15(1):9244

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Gut microbiota-derived acetic acids promoted sepsis-induced acute respiratory distress syndrome by delaying neutrophil apoptosis through FABP4.

Xuan W, Wu X, Zheng L, Jia H, Zhang X, Zhang X, Cao B
Cellular and molecular life sciences : CMLS 2024 Oct 25;81(1):438

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Targeting TGR5 to mitigate liver fibrosis: Inhibition of hepatic stellate cell activation through modulation of mitochondrial fission.

Sun L, Shao Y, Zhuang Z, Liu Z, Liu M, Qu C, Yang H
International immunopharmacology 2024 Oct 25;140:112831

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ZnO NPs Impair the Viability and Function of Porcine Granulosa Cells Through Autophagy Regulated by ROS Production.

Wang Y, Lv J, Liu G, Yao Q, Wang Z, Liu N, He Y, Il D, Tusupovich JI, Jiang Z
Antioxidants (Basel, Switzerland) 2024 Oct 25;13(11)

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Discovery of CZL-046 with an (S)-3-Fluoropyrrolidin-2-one Scaffold as a p300 Bromodomain Inhibitor for the Treatment of Multiple Myeloma.

Chen Z, Yang H, Zhang Y, Lyu X, Shi Q, Zhang C, Wang X, Wang Z, Zhang Y, Deng Y, Wang Y, Huang Y, Xu Y, Huang X, Li Y
Journal of medicinal chemistry 2024 Oct 24;67(20):18606-18628

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Nonclassical action of Ku70 promotes Treg-suppressive function through a FOXP3-dependent mechanism in lung adenocarcinoma.

Huang Q, Tian N, Zhang J, Song S, Cheng H, Liu X, Zhang W, Ye Y, Du Y, Dai X, Liang R, Li D, Dai SM, Wang C, Chen Z, Zhou Q, Li B
The Journal of clinical investigation 2024 Oct 24;134(23)

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Targeting CDCP1 boost CD8+ T cells-mediated cytotoxicity in cervical cancer via the JAK/STAT signaling pathway.

Huang H, Pan Y, Mai Q, Zhang C, Du Q, Liao Y, Qin S, Chen Y, Huang J, Li J, Liu T, Zou Q, Zhou Y, Yuan L, Wang W, Liang Y, Pan CY, Liu J, Yao S
Journal for immunotherapy of cancer 2024 Oct 24;12(10)

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Protective effect of 8-Gingerol, a potent constituent of ginger, on acute lung injury following hemorrhagic shock in rats.

Lian P, Huan Z, Wang Y, Yao H, Han S, Ge X
Experimental animals 2024 Oct 23;73(4):446-457

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Ubiquitin-like 4A alleviates the progression of intracerebral hemorrhage by regulating oxidative stress and mitochondrial damage.

Li D, Wang L, Shi S, Deng X, Zeng X, Li Y, Li S, Bai P
Experimental animals 2024 Oct 23;73(4):421-432

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Non-nutritive Sweetener Aspartame Disrupts Circadian Behavior and Causes Memory Impairment in Mice.

Bai H, Zuo X, Zhao C, Zhang S, Feng X
Journal of agricultural and food chemistry 2024 Oct 23;72(42):23478-23492

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The deficient CLEC5A ameliorates the behavioral and pathological deficits via the microglial Aβ clearance in Alzheimer's disease mouse model.

Lin YY, Chang WH, Hsieh SL, Cheng IH
Journal of neuroinflammation 2024 Oct 23;21(1):273

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Deleting fibroblast growth factor 2 in macrophages aggravates septic acute lung injury by increasing M1 polarization and inflammatory cytokine secretion.

Yi L, Chen Y, Zhang Y, Huang H, Li J, Qu Y, Weng T, Chai J
Molecular biomedicine 2024 Oct 22;5(1):50

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Response Surface Methodology Optimization of Exosome-like Nanovesicles Extraction from Lycium ruthenicum Murray and Their Inhibitory Effects on Aβ-Induced Apoptosis and Oxidative Stress in HT22 Cells.

Zhang Y, Lu L, Li Y, Liu H, Zhou W, Zhang L
Foods (Basel, Switzerland) 2024 Oct 20;13(20)

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ST3GAL4 promotes tumorigenesis in breast cancer by enhancing aerobic glycolysis.

Chen X, Su W, Chen J, Ouyang P, Gong J
Human cell 2024 Oct 18;38(1):1

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Selenium supplementation elevated SELENBP1 to inhibit fibroblast activation in pulmonary arterial hypertension.

Liang B, Lin W, Tang Y, Li T, Chen Q, Zhang W, Zhou X, Ma J, Liu B, Yu Z, Zha L, Zhang M
iScience 2024 Oct 18;27(10):111036

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AMPD3 promotes doxorubicin-induced cardiomyopathy through HSP90α-mediated ferroptosis.

Cheng L, Zhu M, Xu X, Li X, Yao Y, Liu C, He K
iScience 2024 Oct 18;27(10):111005

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Sirtuin 1/sirtuin 3 are robust lysine delactylases and sirtuin 1-mediated delactylation regulates glycolysis.

Du R, Gao Y, Yan C, Ren X, Qi S, Liu G, Guo X, Song X, Wang H, Rao J, Zang Y, Zheng M, Li J, Huang H
iScience 2024 Oct 18;27(10):110911

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Magnetic-vortex nanodonuts enhance ferroptosis effect of tumor ablation through an imaging-guided hyperthermia/radiosensitization strategy.

Guo SS, Chen MM, Yang YH, Zhang YY, Pang X, Shi YP, Zhuang YC, Fan DD, Bao JF, Ji ZY
iScience 2024 Oct 18;27(10):110533

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Bioenergetic-active exosomes for cartilage regeneration and homeostasis maintenance.

Liu X, Jiang S, Jiang T, Lan Z, Zhang X, Zhong Z, Wu X, Xu C, Du Y, Zhang S
Science advances 2024 Oct 18;10(42):eadp7872

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Mitochondrial RelA empowers mtDNA G-quadruplex formation for hypoxia adaptation in cancer cells.

Tang GX, Li ML, Zhou C, Huang ZS, Chen SB, Chen XC, Tan JH
Cell chemical biology 2024 Oct 17;31(10):1800-1814.e7

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The Integrated Stress Response Suppresses PINK1-dependent Mitophagy by Preserving Mitochondrial Import Efficiency.

Yang M, Mo Z, Walsh K, Liu W, Guo X
bioRxiv : the preprint server for biology 2024 Oct 17;

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GRASP55 Regulates Sorting and Maturation of the Lysosomal Enzyme β-Hexosaminidase A.

Akaaboune SR, Javed A, Bui S, Wierenga A, Wang Y
bioRxiv : the preprint server for biology 2024 Oct 17;

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Beyond Glycolysis: Aldolase A Is a Novel Effector in Reelin-Mediated Dendritic Development.

Lagani GD, Sha M, Lin W, Natarajan S, Kankkunen M, Kistler SA, Lampl N, Waxman H, Harper ER, Emili A, Beffert U, Ho A
The Journal of neuroscience : the official journal of the Society for Neuroscience 2024 Oct 16;44(42)

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Corilagin improves cognitive impairment in APP/PS1 mice by reducing Aβ generation and enhancing synaptic plasticity.

Chen L, Zhuang Z, Duan H, Lv D, Hong S, Chen P, He B, Shen Z
European journal of pharmacology 2024 Oct 15;981:176893

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Identification of COL3A1 as a candidate protein involved in the crosstalk between obesity and diarrhea using quantitative proteomics and machine learning.

Wang Y, Wang X, Niu X, Han K, Ru N, Xiang J, Linghu E
European journal of pharmacology 2024 Oct 15;981:176881

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Potential involvement of connective tissue growth factor in chondrocytes apoptosis of Kashin-Beck disease.

Yang X, Liu H, Cheng S, Pan C, Cai Q, Chu X, Shi S, Wei W, He D, Cheng B, Wen Y, Jia Y, Tinkov AA, Skalny AV, Zhang F
Ecotoxicology and environmental safety 2024 Oct 15;285:117148

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Short-term respiratory cadmium exposure partially activates pulmonary NLRP3 inflammasome by inducing ferroptosis in mice.

Li Z, Yao YX, Lu X, Peng K, He YZ, Liu ZB, Zhao H, Wang H, Xu DX, Tan ZX
Ecotoxicology and environmental safety 2024 Oct 15;285:117106

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Glutamine metabolism modulates microglial NLRP3 inflammasome activity through mitophagy in Alzheimer's disease.

Zhang Z, Li M, Li X, Feng Z, Luo G, Wang Y, Gao X
Journal of neuroinflammation 2024 Oct 15;21(1):261

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Endothelial pyroptosis-driven microglial activation in choroid plexus mediates neuronal apoptosis in hemorrhagic stroke rats.

Gu L, Chen H, Geng R, Liang T, Chen Y, Wang Z, Ye L, Sun M, Shi Q, Wan G, Chang J, Wei J, Ma W, Xiao J, Bao X, Wang R
Neurobiology of disease 2024 Oct 15;201:106695

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Neuroprotective effect of emodin on Aβ(25-35)-induced cytotoxicity in PC12 cells involves Nrf2/GPX4 and TLR4/p-NF-κB/NLRP3 pathways.

Xia N, Xu L, Xu D, Huang M, Li Y, Mei Z, Yu Z
Brain research 2024 Oct 15;1841:149019

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HIF-1α knockdown suppresses breast cancer metastasis via epithelial mesenchymal transition Abrogation.

Zhao J, Zhang H, Liu Y, Lu G, Wang Z, Mo Q, Wang G, Shen Y, Jiao L
Heliyon 2024 Oct 15;10(19):e37900

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Mitigation of allergic asthma in mice: A compound mixture comprising luteolin, arbutin, and marmesin from Gerbera Piloselloides Herba by suppression of PI3K/Akt pathway.

Liu C, He Y, Zhou K, Wang H, Zhou M, Sun J, Lu Y, Huang Y, Wang Y, Liu T, Li Y
Heliyon 2024 Oct 15;10(19):e37632

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YBX1 promotes epithelial-mesenchymal transition in hepatocellular carcinoma via transcriptional regulation of PLRG1.

Kwon JH, Kim SH
Medical oncology (Northwood, London, England) 2024 Oct 14;41(11):280

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Spinster homolog 2 (SPNS2) deficiency drives endothelial cell senescence and vascular aging via promoting pyruvate metabolism mediated mitochondrial dysfunction.

Tang H, Gao P, Peng W, Wang X, Wang Z, Deng W, Yin K, Zhu X
Cell communication and signaling : CCS 2024 Oct 11;22(1):492

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Herpes Simplex Virus Type 2 Blocks IFN-β Production through the Viral UL24 N-Terminal Domain-Mediated Inhibition of IRF-3 Phosphorylation.

Zhang B, Li Y, Yang P, He S, Li W, Li M, Hu Q, Zhang M
Viruses 2024 Oct 11;16(10)

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The Altered Proteomic Landscape in Renal Tubular Epithelial Cells under High Oxalate Stimulation.

Hong SY, Qin BL
Biology 2024 Oct 11;13(10)

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Continuous Theta Burst Stimulation Inhibits Oxidative Stress-Induced Inflammation and Autophagy in Hippocampal Neurons by Activating Glutathione Synthesis Pathway, Improving Cognitive Impairment in Sleep-Deprived Mice.

Zhang Y, Zhang C, Dai Q, Ma R
Neuromolecular medicine 2024 Oct 10;26(1):40

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TRIM33 promotes glycolysis through regulating P53 K48-linked ubiquitination to promote esophageal squamous cell carcinoma growth.

Xia T, Meng L, Xu G, Sun H, Chen H
Cell death & disease 2024 Oct 10;15(10):740

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Inhibition of primary cilia-hedgehog signaling axis triggers autophagic cell death and suppresses malignant progression of VHL wild-type ccRCC.

Tian S, Du S, Wang C, Zhang Y, Wang H, Fan Y, Gao Y, Gu L, Huang Q, Wang B, Ma X, Zhang X, Huang Y
Cell death & disease 2024 Oct 10;15(10):739

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Castration reshapes the liver by altering fatty acid composition and metabolism in male mice.

Yao H, Li D, Cao X, Han X, He J, Cheng D, Shang J, Song T, Zeng X
Biochemical and biophysical research communications 2024 Oct 1;727:150319

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USP18 promotes the proliferation, invasion, and migration of head and neck squamous cell carcinoma by deubiquitinating PLK1.

Geng L, Liu F, Yang L, Liu Y, Wu G
Experimental cell research 2024 Oct 1;442(2):114284

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Oxytocin attenuates neuroinflammation-induced anxiety through restoration of excitation and inhibition balance in the anterior cingulate cortex in mice.

Shi CN, Wu XM, Gao YZ, Ma DQ, Yang JJ, Ji MH
Journal of affective disorders 2024 Oct 1;362:341-355

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Actin cytoskeleton and associated myosin motors within the renal epithelium.

Busselman BW, Ratnayake I, Terasaki MR, Thakkar VP, Ilyas A, Otterpohl KL, Zimmerman JL, Chandrasekar I
American journal of physiology. Renal physiology 2024 Oct 1;327(4):F553-F565

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Characterization of Ucp1-iCre knockin mice reveals the recombination activity in male germ cells.

Li MY, Lu M, Cao DM, Han Q, Ma XH, Wei CC, Zhang WJ
American journal of physiology. Endocrinology and metabolism 2024 Oct 1;327(4):E544-E551

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Triclosan exposure causes abnormal bile acid metabolism through IL-1β-NF-κB-Fxr signaling pathway.

Liu J, Xu F, Guo M, Song Y
Ecotoxicology and environmental safety 2024 Oct 1;284:116989

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Intra-amniotic delivery of tropomodulin 3 rescues cell apoptosis induced by miR-200b-3p upregulation via non-canonical nuclear factor kappa B pathways in ethylene thiourea induced anorectal malformations fetal rat.

Liu P, Li Y, Yao Y, Wang W, Jia H, Bai Y, Yuan Z, Yang Z
Ecotoxicology and environmental safety 2024 Oct 1;284:116918

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Hesperetin alleviates aflatoxin B1 induced liver toxicity in mice: Modulating lipid peroxidation and ferritin autophagy.

Song C, Wang Z, Cao J, Dong Y, Chen Y
Ecotoxicology and environmental safety 2024 Oct 1;284:116854

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Emerging perfluoroalkyl substances retard skeletal growth by accelerating osteoblasts senescence via ferroptosis.

Wang X, Wang K, Mao W, Fan Z, Liu T, Hong R, Chen H, Pan C
Environmental research 2024 Oct 1;258:119483

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Advanced machine learning unveils CD8 + T cell genetic markers enhancing prognosis and immunotherapy efficacy in breast cancer.

Ma H, Shi L, Zheng J, Zeng L, Chen Y, Zhang S, Tang S, Qu Z, Xiong X, Zheng X, Yin Q
BMC cancer 2024 Oct 1;24(1):1222

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p38 MAPK inhibitor SB202190 suppresses ferroptosis in the glutamate-induced retinal excitotoxicity glaucoma model.

Feng L, Wang C, Zhang C, Zhang W, Zhu W, He Y, Xia Z, Song W
Neural regeneration research 2024 Oct 1;19(10):2299-2309

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Engineered extracellular vesicles enable high-efficient delivery of intracellular therapeutic proteins.

Ma D, Xie A, Lv J, Min X, Zhang X, Zhou Q, Gao D, Wang E, Gao L, Cheng L, Liu S
Protein & cell 2024 Oct 1;15(10):724-743

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NOD2 reduces the chemoresistance of melanoma by inhibiting the TYMS/PLK1 signaling axis.

Yun F, Wu N, Yi X, Zhang X, Feng Y, Ni Q, Gai Y, Li E, Yang Z, Zhang Q, Sai B, Kuang Y, Zhu Y
Cell death & disease 2024 Oct 1;15(10):720

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Serum apolipoprotein H determines ferroptosis resistance by modulating cellular lipid composition.

He X, Zhang J, Huang M, Wang J, Yang S, Yu X, Xu Y, Yang W
Cell death & disease 2024 Oct 1;15(10):718

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Improvement of MASLD and MASH by suppression of hepatic N-acetyltransferase 10.

Yang Y, Lu J, Liu Y, Zhang N, Luo Y, Ma M, Dong Z, Zhang S, Zheng MH, Ruan CC, Wan X, Hu C, Lu Y, Ma X, Zhou B
Molecular metabolism 2024 Nov;89:102030

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Downregulation of short-stature homeobox protein 2 suppresses gastric cancer cell growth and stemness in vitro and in vivo via inactivating wnt/β-catenin signaling.

Chen X, Li S, Sun B
Drug development research 2024 Nov;85(7):e70006

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Binding of α-synuclein to ACO2 promotes progressive mitochondrial dysfunction in Parkinson's disease models.

Jiao J, Gao G, Zhu J, Wang C, Liu L, Yang H
Redox biology 2024 Nov;77:103399

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Gut microbiome and metabolites mediate the benefits of caloric restriction in mice after acute kidney injury.

Zhu XX, Fu X, Meng XY, Su JB, Zheng GL, Xu AJ, Chen G, Zhang Y, Liu Y, Hou XH, Qiu HB, Sun QY, Hu JY, Lv ZL, Wang Y, Jiang HB, Bao N, Han ZJ, Lu QB, Sun HJ
Redox biology 2024 Nov;77:103373

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Rituximab induces ferroptosis and RSL3 overcomes rituximab resistance in diffuse large B-cell lymphoma cells.

Wu H, Zou L, Jin Y, Wang G, Cho WC, Li W, Cai Y, Song G
Archives of biochemistry and biophysics 2024 Nov;761:110188

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STC2 knockdown inhibits cell proliferation and glycolysis in hepatocellular carcinoma through promoting autophagy by PI3K/Akt/mTOR pathway.

Li D, Xiong Y, Li M, Long L, Zhang Y, Yan H, Xiang H
Archives of biochemistry and biophysics 2024 Nov;761:110149

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Sulforaphane Improves Liver Metabolism and Gut Microbiota in Circadian Rhythm Disorder Mice Models Fed With High-Fat Diets.

He C, Chen M, Jiang X, Ren J, Ganapathiraju SV, Lei P, Yang H, Pannu PR, Zhao Y, Zhang X
Molecular nutrition & food research 2024 Nov;68(21):e2400535

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Yeast Extract Peptides Alleviate Depression in Chronic Restraint Stress Rats by Alleviating Hippocampal Neuronal Apoptosis and Dysbiosis of the Gut Microbiota.

Zou Z, Xiao N, Chen Z, Lin X, Li Y, Li P, Cheng Q, Du B
Molecular nutrition & food research 2024 Nov;68(21):e2300467

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Micellar curcumol for maintenance therapy of ovarian cancer by activating the FOXO3a.

Wang J, Chen B, Yang J, Tang Q, Zhong Y, Du J, Wang S, Wu Q, Lu Y, Song Y
Nanomedicine : nanotechnology, biology, and medicine 2024 Nov;62:102789

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Metformin suppresses metabolic dysfunction-associated fatty liver disease by ferroptosis and apoptosis via activation of oxidative stress.

Li Z, Cui C, Xu L, Ding M, Wang Y
Free radical research 2024 Nov;58(11):686-701

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Atg16l2 augments Nlrc4 inflammasome activation by facilitating NAIPs-NLRC4 association.

Wen Z, Yuan T, Liu J, Wang D, Ni J, Yan X, Tang J, Tang J, Wu X, Wang Z
European journal of immunology 2024 Nov;54(11):e2451078

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Hexavalent chromium reduces testosterone levels by impairing lipophagy and disrupting lipid metabolism homeostasis: Based on a metabolomic analysis.

Xue Q, Zhang L, Wang R, Xu J, Wang C, Gao S, Fang X, Meng C, Lu R, Guo L
Toxicology 2024 Nov;508:153908

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Phase separation of phospho-HDAC6 drives aberrant chromatin architecture in triple-negative breast cancer.

Lu B, Qiu R, Wei J, Wang L, Zhang Q, Li M, Zhan X, Chen J, Hsieh IY, Yang C, Zhang J, Sun Z, Zhu Y, Jiang T, Zhu H, Li J, Zhao W
Nature cancer 2024 Nov;5(11):1622-1640

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DEAD/H-box helicase 11 is transcriptionally activated by Yin Yang-1 and accelerates oral squamous cell carcinoma progression.

Yang G, Shi X, Zhang M, Wang K, Tian X, Wang X
Cell biology international 2024 Nov;48(11):1731-1742

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MicroRNAs modulate SARS-CoV-2 infection of primary human hepatocytes by regulating the entry factors ACE2 and TMPRSS2.

Khanal R, Heinen N, Bogomolova A, Meister TL, Herrmann ST, Westhoven S, Nocke MK, Todt D, Jockenhövel F, Klein IM, Hartmann L, Vondran FWR, Steinmann E, Zimmer G, Ott M, Brown RJP, Sharma AD, Pfaender S
Liver international : official journal of the International Association for the Study of the Liver 2024 Nov;44(11):2983-2995

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Influences of TiO(2) nanoparticle and fipronil co-exposure on metabolite profiles in mouse intestines.

Wang C, Zhou Z, He Y, Li J, Cao Y
Journal of applied toxicology : JAT 2024 Nov;44(11):1793-1803

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Local TSH/TSHR signaling promotes CD8(+) T cell exhaustion and immune evasion in colorectal carcinoma.

Zeng S, Hu H, Li Z, Hu Q, Shen R, Li M, Liang Y, Mao Z, Zhang Y, Zhan W, Zhu Q, Wang F, Xiao J, Xu B, Liu G, Wang Y, Li B, Xu S, Zhang Z, Zhang C, Wang Z, Liang L
Cancer communications (London, England) 2024 Nov;44(11):1287-1310

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CypA/TAF15/STAT5A/miR-514a-3p feedback loop drives ovarian cancer metastasis.

Li Y, Yang H, Li A, Chen B, Wang Y, Song Z, Tan H, Li H, Feng Q, Zhou Y, Li S, Zeng L, Lan T
Oncogene 2024 Nov;43(49):3570-3585

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Targeting CircAURKA prevents colorectal cancer progression via enhancing CTNNB1 protein degradation.

Sun Z, Dang P, Guo Y, Liu S, Hu S, Sun H, Xu Y, Wang W, Chen C, Liu J, Ji Z, Liu Y, Hu J
Oncogene 2024 Nov;43(46):3388-3401

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SUV39H1 epigenetically modulates the MCPIP1-AURKA signaling axis to enhance neuroblastoma tumorigenesis.

Li M, Sun F, Wang J, Lu S, Que Y, Song M, Chen H, Xiong X, Xie W, Zhu J, Huang J, Zhang Y, Zhang Y
Oncogene 2024 Nov;43(45):3306-3320

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Blocking lactate regulation of the Grhl2/SLC31A1 axis inhibits trophoblast cuproptosis and preeclampsia development.

Shen XY, Huang J, Chen LL, Sha MT, Gao J, Xin H
Journal of assisted reproduction and genetics 2024 Nov;41(11):3201-3212

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Ginkgo Flavone Aglycone Ameliorates Atherosclerosis via Inhibiting Endothelial Pyroptosis by Activating the Nrf2 Pathway.

Chen X, Yang Z, Liao M, Zhao Q, Lu Y, Li Q, Liu S, Li S, Chen J, He Y
Phytotherapy research : PTR 2024 Nov;38(11):5458-5473

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Inhibition of the AP-1/TFPI2 axis contributes to alleviating cerebral ischemia/reperfusion injury by improving blood-brain barrier integrity.

Cao Y, Xing R, Li Q, Bai Y, Liu X, Tian B, Li X
Human cell 2024 Nov;37(6):1679-1695

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Mechanical Stress-Oxidative Stress Axis: Biological Basis in the Vaginal Wall and Pelvic Floor Muscles of Rats with Simulated Birth Injury.

Wang Q, Wu X, Wang S, Xie B, Sun X, Wang J
International urogynecology journal 2024 Nov;35(11):2141-2152

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Metformin attenuates PM(2.5)-induced oxidative stress by inhibiting the AhR/CYP1A1 pathway in proximal renal tubular epithelial cells.

Cui J, Chen W, Zhang D, Lu M, Huang Z, Yi B
Toxicology mechanisms and methods 2024 Nov;34(9):1022-1034

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MiR-424-5p Inhibits Proliferation, Migration, Invasion and Angiogenesis of the HTR-8/SVneo Cells Through Targeting LRP6 Mediated β-catenin.

Fei K, Zhang H, Zhang W, Liao C
Reproductive sciences (Thousand Oaks, Calif.) 2024 Nov;31(11):3428-3439

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Dysregulated Wnt/β-catenin signaling confers resistance to cuproptosis in cancer cells.

Liu YT, Chen L, Li SJ, Wang WY, Wang YY, Yang QC, Song A, Zhang MJ, Mo WT, Li H, Hu CY, Sun ZJ
Cell death and differentiation 2024 Nov;31(11):1452-1466

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Upregulation of nuclear protein Hemgn by transcriptional repressor Gfi1 through repressing PU.1 contributes to the anti-apoptotic activity of Gfi1.

G C B, Hoyt LJ, Dovat S, Dong F
The Journal of biological chemistry 2024 Nov;300(11):107860

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Porphyromonas gingivalis OMVs promoting endothelial dysfunction via the STING pathway in periodontitis.

Chen Z, Cao Y, Jiang W, Yan Z, Cai G, Ye J, Wang H, Liu L
Oral diseases 2024 Nov;30(8):5461-5474

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Macrophage-derived exosomes rescue the TNF-ɑ-suppressed osteo-/cementogenic differentiation of hPDLCs.

Deng Y, Xiao J, Huang X, Cao Z
Oral diseases 2024 Nov;30(8):5232-5242

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Rapamycin alleviates irradiation-induced parotid injury by enhancing the whole gland homeostasis.

Zhu Z, Song J, Zhang C, Zhang J, Shan Z
Oral diseases 2024 Nov;30(8):5050-5061

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Oroxylin A, a broad‑spectrum anticancer agent, relieves monocrotaline‑induced pulmonary arterial hypertension by inhibiting the Warburg effect in rats.

Wang Y, Fan Y, Zhou Y, Chen T, Xu S, Liu J, Li L
Molecular medicine reports 2024 Nov;30(5)

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IL-10 upregulates SOCS3 to inhibit type I interferon signaling to promote PoRVA replication in intestinal epithelial cells.

Liu H, Zhao Y, Du H, Hao P, Tian H, Wang K, Qiu Y, Dong H, Du Q, Tong D, Huang Y
Veterinary microbiology 2024 Nov;298:110259

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PRRSV infection inhibits CSFV C-strain replication via GSDMD-mediated pyroptosis.

Jiang R, Chen D, Zhang Y, Zhou L, Ge X, Han J, Guo X, Yang H
Veterinary microbiology 2024 Nov;298:110243

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The network interactions between the porcine deltacoronavirus nucleocapsid protein and host cellular proteins.

Jiang H, Jia M, Xiong J, Zhao C, Wang T, Kong L, Peng Q
Veterinary microbiology 2024 Nov;298:110225

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Molecular cloning and functional characterization of mitochondrial RNA splicing 2 in fish Megalobrama amblycephala, and its potential roles in magnesium homeostasis and mitochondrial function.

Zhang L, Liu ZS, Dong YZ, He CF, Zhang DD, Jiang GZ, Liu WB, Li XF
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2024 Nov;297:111727

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Bilobalide ameliorates osteoporosis by influencing the SIRT3/NF-κB axis in osteoclasts and promoting M2 polarization in macrophages.

Qin Y, Hu C, Jin J, Chao Y, Wang D, Xia F, Ruan C, Jiang C, Guan M, Zou C
International journal of biological macromolecules 2024 Nov;281(Pt 4):136504

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Polysaccharides from Sacha Inchi shell reduces renal fibrosis in mice by modulating the TGF-β1/Smad pathway and intestinal microbiota.

Chen Y, Huang J, Wang H, Cui H, Liang Z, Huang D, Deng X, Du B, Li P
International journal of biological macromolecules 2024 Nov;280(Pt 4):136039

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Schizophyllum commune fruiting body polysaccharides inhibit glioma by mediating ARHI regulation of PI3K/AKT signalling pathway.

Zheng SX, Chen JP, Liang RS, Zhuang BB, Wang CH, Zhang GL, Shi SS, Chen J
International journal of biological macromolecules 2024 Nov;279(Pt 3):135326

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The role of phlorizin liposome-embedded oxidized sodium alginate/carboxymethyl chitosan in diabetic wound healing.

Wu X, Ding C, Liu X, Ding Q, Zhang S, Wang Y, Xin C, Wei H, Mao R, Zhang G, Zhao T, Liu W
International journal of biological macromolecules 2024 Nov;279(Pt 3):135324

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Spatiotemporal coordination of actin regulators generates invasive protrusions in cell-cell fusion.

Lu Y, Walji T, Ravaux B, Pandey P, Yang C, Li B, Luvsanjav D, Lam KH, Zhang R, Luo Z, Zhou C, Habela CW, Snapper SB, Li R, Goldhamer DJ, Schmidtke DW, Pan D, Svitkina TM, Chen EH
Nature cell biology 2024 Nov;26(11):1860-1877

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SIRT2 regulates high mobility group protein B1 nucleoplasmic shuttle and degradation via deacetylation in microglia.

Xing WQ, Piao XJ, Han Q, Shi HY, Wu WC, Si F, Lu JJ, Zhou TZ, Guo JR, Li SZ, Xu B
Journal of cellular physiology 2024 Nov;239(11):e31364

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Histone β-hydroxybutyrylation is critical in reversal of sarcopenia.

Wang Q, Lan X, Ke H, Xu S, Huang C, Wang J, Wang X, Huang T, Wu X, Chen M, Guo Y, Zeng L, Tian XL, Xiang Y
Aging cell 2024 Nov;23(11):e14284

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Piperlongumine, a natural alkaloid from Piper longum L. ameliorates metabolic-associated fatty liver disease by antagonizing the thromboxane A(2) receptor.

Dai Y, Chen J, Fang J, Liang S, Zhang H, Li H, Chen W
Biochemical pharmacology 2024 Nov;229:116518

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Identification of human-specific amino acid residues governing atenolol transport via organic cation transporter 2.

Hosooka A, Yasujima T, Murata A, Yamashiro T, Yuasa H
Biochemical pharmacology 2024 Nov;229:116514

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Dysregulated lncSNHG12 suppresses the invasion and migration of trophoblasts by regulating Dio2/Snail axis to involve in recurrent spontaneous abortion.

Wang Z, Yan S, Liao S, Zhang Y, Wu S, Zhou M, Jin W, Zhang Y, Qi X, Yang C, Yang J, Ding J
Biochemical pharmacology 2024 Nov;229:116459

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Rack1 regulates B-cell development and function by binding to and stabilizing the transcription factor Pax5.

Zhang X, Ma C, Lu Y, Wang J, Yun H, Jiang H, Wu M, Feng X, Gai W, Xu G, Deng H, Feng J, Liu W, Shi T, Cheng Q, Zhang J
Cellular & molecular immunology 2024 Nov;21(11):1282-1295

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Small Intestinal Submucosa Hydrogel Loaded With Gastrodin for the Repair of Achilles Tendinopathy.

Zhang X, Li M, Mao X, Yao Z, Zhu W, Yuan Z, Gao X, Pan S, Zhang Y, Zhao J, Mao H
Small (Weinheim an der Bergstrasse, Germany) 2024 Nov;20(47):e2401886

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Polyamines mediate cellular energetics and lipid metabolism through mitochondrial respiration to facilitate virus replication.

Cruz-Pulido YE, LoMascolo NJ, May D, Hatahet J, Thomas CE, Chu AKW, Stacey SP, Villanueva Guzman MDM, Aubert G, Mounce BC
PLoS pathogens 2024 Nov;20(11):e1012711

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CDKN1A promotes Cis-induced AKI by inducing cytoplasmic ROS production and ferroptosis.

Gao Q, Chen JM, Li CS, Zhan JY, Yin XD, Li BS, Dong HL, Luo LX, Li ZL
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Nov;193:115003

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Targeting delivery of mifepristone to endometrial dysfunctional macrophages for endometriosis therapy.

Zhang M, Ye Y, Chen Z, Wu X, Chen Y, Zhao P, Zhao M, Zheng C
Acta biomaterialia 2024 Nov;189:505-518

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COPZ1 regulates ferroptosis through NCOA4-mediated ferritinophagy in lung adenocarcinoma.

Wu A, Yang H, Xiao T, Gu W, Li H, Chen P
Biochimica et biophysica acta. General subjects 2024 Nov;1868(11):130706

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Expediting the development of robust 5-FU-resistant colorectal cancer models using innovative combined in vivo and in vitro strategies.

Shao M, Gao Y, Xu X, Shi J, Wang Z, Du J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117576

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Melittin treatment suppressed malignant NSCLC progression through enhancing CTSB-mediated hyperautophagy.

Wang Y, Yuan T, He L, Huang J, Wilfred N, Yang W, Jin M, Huang G, Lu C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117573

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Rutaecarpine alleviates inflammation and fibrosis by targeting CK2α in diabetic nephropathy.

Chen J, Hu ZY, Ma Y, Jiang S, Yin JY, Wang YK, Wu YG, Liu XQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117499

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Local anesthetic tetracaine hydrochloride induces pyroptosis via caspase-3/gasdermin E in uveal melanoma.

Yi P, Zhang R, Qin Z, Zhao X, Wu C, Yu Y, Liu L, Zhou J, Feng J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117471

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SARS-CoV-2 NSP14 induces AP-1 transcriptional activity via its interaction with MEK.

Li W, Wang Y, Peng Q, Shi Y, Wan P, Yao Y, Bai T, Ma Y, Shu X, Liu Y, Sun B
Molecular immunology 2024 Nov;175:1-9

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Cancer-Associated Endocrine Cells Participate in Pancreatic Carcinogenesis.

Chen Y, Yin X, Xu R, Ruze R, Song J, Yin C, Hu C, Wang C, Xu Q, Zhao Y
Gastroenterology 2024 Nov;167(6):1167-1182.e23

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Luteolin detoxifies DEHP and prevents liver injury by degrading Uroc1 protein in mice.

Wang H, Zhao Z, Song M, Zhang W, Liu C, Chen S
EMBO molecular medicine 2024 Nov;16(11):2699-2724

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Emodin alleviates lung injury via the miR-217-5p/Sirt1 axis in rats with severe acute pancreatitis.

Zhang Z, Luo Y, Zhuang X, Gao H, Yang Q, Chen H
Journal of pharmacological sciences 2024 Nov;156(3):188-197

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The role of the microbiota-gut-brain axis in methamphetamine-induced neurotoxicity: Disruption of microbial composition and short-chain fatty acid metabolism.

Chen L, Zhang K, Liu J, Li X, Liu Y, Ma H, Yang J, Li J, Chen L, Hsu C, Zeng J, Xie X, Wang Q
Acta pharmaceutica Sinica. B 2024 Nov;14(11):4832-4857

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Chaiqin chengqi decoction treatment mitigates hypertriglyceridemia-associated acute pancreatitis by modulating liver-mediated glycerophospholipid metabolism.

Wen Y, Li Y, Liu T, Huang L, Yao L, Deng D, Luo W, Cai W, Zhong S, Jin T, Yang X, Wang Q, Wang W, Xue J, Mukherjee R, Hong J, Phillips AR, Windsor JA, Sutton R, Li F, Sun X, Huang W, Xia Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155968

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Jiao-tai-wan and its effective component-coptisine alleviate cognitive impairment in db/db mice through the JAK2/STAT3 signaling pathway.

Nie K, Gao Y, Wang H, Su H, Chen S, Jiang X, Dong H, Tang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155954

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Phillyrin promotes autophagosome formation in A53T-αSyn-induced Parkinson's disease model via modulation of REEP1.

Qi LF, Liu Y, Liu S, Xiang L, Liu Z, Liu Q, Zhao JQ, Xu X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155952

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Mn(II)-Aloe-Emodin Nanoscale Coordination Polymer Enhances Ferroptosis by Synergistically Enhancing Reactive Oxygen Species Generation via the Nrf2-GPX4 Axis.

Yang X, Li C, Ge M, Li X, Zhao W, Guo H, Nie H, Liu J
Advanced healthcare materials 2024 Nov;13(28):e2400474

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PlexinA1 (PLXNA1) as a novel scaffold protein for the engineering of extracellular vesicles.

Zhao H, Li Z, Liu D, Zhang J, You Z, Shao Y, Li H, Yang J, Liu X, Wang M, Wu C, Chen J, Wang J, Kong G, Zhao L
Journal of extracellular vesicles 2024 Nov;13(11):e70012

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Human placental mesenchymal stromal cells alleviate intestinal oxidative damage in mice with graft-versus-host disease via CD73/adenosine/PI3K/Akt/GSK-3β axis.

Han K, Wang F, Ma X, Wu Y, Zhang H, Zhao Y, Wang H, Ma J, Luan X
Cellular signalling 2024 Nov;123:111372

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Sirt6 Mono-ADP-Ribosylates YY1 to Promote Dystrophin Expression for Neuromuscular Transmission.

Zhang W, Bai L, Xu W, Liu J, Chen Y, Lin W, Lu H, Wang B, Luo B, Peng G, Zhang K, Shen C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(44):e2406390

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SNPs Give LACTB Oncogene-Like Functions and Prompt Tumor Progression via Dual-Regulating p53.

Huang G, Zhang J, Xu Y, Wu F, Fu Y, Zhang X, Yin H, You Y, Zhao P, Liu W, Shen J, Yin J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(43):e2405907

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IL6 Derived from Macrophages under Intermittent Hypoxia Exacerbates NAFLD by Promoting Ferroptosis via MARCH3-Led Ubiquitylation of GPX4.

Cai W, Wu S, Ming X, Li Z, Pan D, Yang X, Yang M, Yuan Y, Chen X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(41):e2402241

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Co-exposure of polyvinyl chloride microplastics with cadmium promotes nonalcoholic fatty liver disease in female ducks through oxidative stress and glycolipid accumulation.

Chen Y, Jin H, Ali W, Zhuang T, Sun J, Wang T, Song J, Ma Y, Yuan Y, Bian J, Liu Z, Zou H
Poultry science 2024 Nov;103(11):104152

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A dual role for PSIP1/LEDGF in T cell acute lymphoblastic leukemia.

Demoen L, Matthijssens F, Reunes L, Palhais B, Lintermans B, T'Sas S, Fijalkowski I, Taminau J, Akele MZ, Van Belle S, Taghon T, Deforce D, Van Nieuwerburgh F, Berx G, Ntziachristos P, Debyser Z, Durinck K, Pieters T, Goossens S, Van Vlierberghe P
Science advances 2024 Nov;10(44):eado6765

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Compromised actin dynamics underlie the orofacial cleft in Baraitser-Winter Cerebrofrontofacial syndrome with a variant in ACTB.

Tsujimoto T, Ou Y, Suzuki M, Murata Y, Inubushi T, Nagata M, Ishihara Y, Yonei A, Miyashita Y, Asano Y, Sakai N, Sakata Y, Ogino H, Yamashiro T, Kurosaka H
Human molecular genetics 2024 Nov 8;33(22):1975-1985

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Enhancing DOX efficacy against NSCLC through UDCA-mediated modulation of the TGF-β/MAPK autophagy pathways.

Li Y, Zhao H, Shen Z, Zheng Y, Jiang Y, Song Y, Cai Y
Scientific reports 2024 Nov 8;14(1):27169

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Differential proteomic profiles of exosomes in pediatric and adult adamantinomatous craniopharyngioma cyst fluid.

Chen Y, Wang Z, Huang Q, Wang Y, Yan F, Xiang S, Xu L, Chen Y, Liu X, Chen G, Li M, Zhou Y
Molecular biology reports 2024 Nov 7;51(1):1126

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Host-derived Lactobacillus plantarum alleviates hyperuricemia by improving gut microbial community and hydrolase-mediated degradation of purine nucleosides.

Fu Y, Luo XD, Li JZ, Mo QY, Wang X, Zhao Y, Zhang YM, Luo HT, Xia DY, Ma WQ, Chen JY, Wang LH, Deng QY, Ben L, Kashif Saleemi M, Jiang XZ, Chen J, Miao K, Lin ZP, Zhang P, Ye H, Cao QY, Zhu YW, Yang L, Tu Q, Wang W
eLife 2024 Nov 7;13

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Retinol binding protein 4 restricts PCV2 replication via selective autophagy degradation of viral ORF1 protein.

Han Q, Zhao H, Chen M, Xue W, Li J, Sun L, Shang Y
Communications biology 2024 Nov 5;7(1):1438

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Novel EGFR inhibitors against resistant L858R/T790M/C797S mutant for intervention of non-small cell lung cancer.

Wang X, Qin Z, Qiu W, Xu K, Bai Y, Zeng B, Ma Y, Yang S, Shi Y, Fan Y
European journal of medicinal chemistry 2024 Nov 5;277:116711

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Ren-Shen-Bu-Qi decoction alleviates exercise fatigue through activating PI3K/AKT/Nrf2 pathway in mice.

Chen Y, Gao T, Bai J, Zhang W, Zhou Y, Zhao R, Deng Y, Liu X, Huang Z, Wang S, Shen C, Liu S, Guo J
Chinese medicine 2024 Nov 5;19(1):154

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Cancer-Associated Fibroblast-Derived FGF7 Promotes Clear Cell Renal Cell Carcinoma Progression and Macrophage Infiltration.

Jia M, Xie M, Luo X, Wang H, Duan C, Lai W, Dai R, Wang R
Cells 2024 Nov 5;13(22)

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N-terminal acetylation of transcription factor LIP induces immune therapy resistance via suppression of PD-L1 expression in non-small cell lung cancer.

He X, Liu Y, Gao X, Tang F, Tian Y, Gong S, Shen J, Wang A, Sun L, Wei W, Weng L
Journal for immunotherapy of cancer 2024 Nov 29;12(11)

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A brain-to-liver signal mediates the inhibition of liver regeneration under chronic stress in mice.

Zhou Y, Lin X, Jiao Y, Yang D, Li Z, Zhu L, Li Y, Yin S, Li Q, Xu S, Tang D, Zhang S, Yu W, Gao P, Yang L
Nature communications 2024 Nov 28;15(1):10361

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Naphthoquinone Derivatives from the Endophytic Fungus Fusarium solani Induce Pancreatic Cancer Cells Apoptosis via Targeting EGFR-Mediated PI3K/Akt Pathway.

Gao LL, Fang XT, Zhao SH, Hui CX, Huang WW, Gao YQ, Gao JM
Journal of agricultural and food chemistry 2024 Nov 27;72(47):26209-26223

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Low-Medium Polarity Ginsenosides from Wild Ginseng Improves Immunity by Activating the AhR/MAPK Pathway through Tryptophan Metabolism Driven by Gut Microbiota.

Zhang M, Ma L, Luo J, Ren T, Liu S, Pan L, Bao Y, Li F, Dai Y, Pi Z, Yue H, Zheng F
Journal of agricultural and food chemistry 2024 Nov 27;72(47):26142-26154

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The AXL-mediated modulation of myeloid-derived suppressor cells (MDSC) in nasopharyngeal carcinoma.

Lv Y, Zhu J, Ge S, Jiang T, Xu Y, Yao W, Jiang C
Medical oncology (Northwood, London, England) 2024 Nov 27;42(1):17

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In vivo silencing of intestinal DMT1 mitigates iron loading in β-thalassemia intermedia (Hbbth3/+) mice.

Yu Y, Woloshun RR, Lee JK, Ebea-Ugwuanyi PO, Shine JS, Zhu S, He Y, Collins JF
Blood advances 2024 Nov 26;8(22):5753-5765

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Enhancing radiosensitivity in osteosarcoma via CDKN2C overexpression: A mechanism involving G1 phase arrest mediated by inhibition of CDK4 expression and Thr172 phosphorylation.

Lian Q, Zhao H, Wang B, Ling P, Li J, Dai P, Ge J, Su X, Wang Z, Qiao S
Biochemical and biophysical research communications 2024 Nov 26;735:150840

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Salidroside promotes liver regeneration after partial hepatectomy in mice by modulating NLRP3 inflammasome-mediated pyroptosis pathway.

Zhang S, Yu M, Wang F, Li S, Li X, Hu H, Zhang Z, Zhu X, Tian W
Biochemical and biophysical research communications 2024 Nov 26;735:150678

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Mitochondrial miRNAs and fibromyalgia: new biomarker candidates.

Rasulova K, Dilek B, Kavak DE, Pehlivan M, Kizildag S
Molecular biology reports 2024 Nov 26;52(1):16

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ZDHHC3-mediated SCAP S-acylation promotes cholesterol biosynthesis and tumor immune escape in hepatocellular carcinoma.

Wu M, Zhou X, Zhou X, Wang G, Zeng Y, Li J, Prochownik EV, Wang F, Li Y
Cell reports 2024 Nov 26;43(11):114962

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Novel biallelic variants in IREB2 cause an early-onset neurodegenerative disorder in a Chinese pedigree.

Guo Z, Huo D, Shao Y, Yang W, Wang J, Zhang Y, Xiao H, Hao B, Liao S
Orphanet journal of rare diseases 2024 Nov 25;19(1):435

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Oxidative Injury to Lung Mitochondrial DNA is a Key Contributor for the Development of Chemical Lung Injury.

Dubey S, Yu Z, Stephens EM, Lazrak A, Ahmad I, Aggarwal S, Andrabi S, Hossain MI, Jilling T, Fernadez SR, Bartels JL, Lapi SE, Mobley J, Pastukh VM, Gillespie M, Matalon S
bioRxiv : the preprint server for biology 2024 Nov 25;

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Propafenone facilitates mitochondrial-associated ferroptosis and synergizes with immunotherapy in melanoma.

Zhou Q, Dian Y, He Y, Yao L, Su H, Meng Y, Sun Y, Li D, Xiong Y, Zeng F, Liang X, Liu H, Chen X, Deng G
Journal for immunotherapy of cancer 2024 Nov 24;12(11)

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DsbA-L activates TGF-β1/SMAD3 signaling and M2 macrophage polarization by stimulating AKT1 and NLRP3 to promote pulmonary fibrosis.

Wang J, Xia Z, Qing B, Chen Y, Gu L, Chen H, Ge Z, Yuan Y
Molecular medicine (Cambridge, Mass.) 2024 Nov 23;30(1):228

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Effect of Tricin on cardiomyocyte damage caused by diabetic cardiomyopathy (DCM).

Yu R, Zhang Y, Wang T, Duan J, Li X
BMC cardiovascular disorders 2024 Nov 23;24(1):668

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Effects of Saccharomyces boulardii on microbiota composition and metabolite levels in the small intestine of constipated mice.

Tang S, Li J, Li Y, Du H, Zhu W, Zhang R, Wan J
BMC microbiology 2024 Nov 23;24(1):493

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Expression of variant isoforms of the tyrosine kinase SYK differentially regulates cervical cancer progression through PI3K/AKT pathway.

Lin B, Wang Q, Wang X, Wei H, Nie X, Li L, Shi Y
Scientific reports 2024 Nov 23;14(1):29080

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Chaperone-Mediated Autophagy Alleviates Cerebral Ischemia-Reperfusion Injury by Inhibiting P53-Mediated Mitochondria-Associated Apoptosis.

Yang S, Jiang L, Deng L, Luo J, Zhang X, Chen S, Dong Z
Neurochemical research 2024 Nov 22;50(1):29

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Splicing factor SRSF1 attenuates cardiomyocytes apoptosis via regulating alternative splicing of Bcl2L12.

Xie Y, Yang Z, Chen W, Zhong C, Li M, Zhang L, Cheng T, Deng Q, Wang H, Ju J, Du Z, Liang H
Cell & bioscience 2024 Nov 22;14(1):142

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Role of transglutaminase 2 in promoting biglycan synthesis in idiopathic gingival fibromatosis.

Ninomiya Y, Matsuda S, Suzuki S, Hirata-Tsuchiya S, Ueda T, Nakashima F, Yasuda K, Shimada S, Memida T, Yoshimoto T, Yamada S, Ouhara K, Mizuno N
BMC oral health 2024 Nov 21;24(1):1422

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Maresin-1 Ameliorates Sepsis-Induced Microglial Activation Through Modulation of the P38 MAPK Pathway.

Dai M, Sun S, Dai Y, Dou X, Yang J, Chen X, Yang D, Lin Y
Neurochemical research 2024 Nov 20;50(1):26

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Adipose stem cell exosomes, stimulated by pro-inflammatory factors, enhance immune evasion in triple-negative breast cancer by modulating the HDAC6/STAT3/PD-L1 pathway through the transporter UCHL1.

Zhu Q, Zhang K, Cao Y, Hu Y
Cancer cell international 2024 Nov 20;24(1):385

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Role of ferroptosis in mitochondrial damage in diabetic retinopathy.

Malaviya P, Kumar J, Kowluru RA
Free radical biology & medicine 2024 Nov 20;225:821-832

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A glutamine metabolish-associated prognostic model to predict prognosis and therapeutic responses of hepatocellular carcinoma.

Xu H, Pan H, Fang L, Zhang C, Xiong C, Cai W
Biology direct 2024 Nov 20;19(1):118

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Isoleucine Enhanced the Function of the Small Intestinal Mucosal Barrier in Weaned Piglets to Alleviate Rotavirus Infection.

Zhao R, Jiang C, Yuan Y, Zhang S, Ghonaim AH, Che C, Li X, Jin M, Jin E, Zeng X, Li S, Ren M
Animals : an open access journal from MDPI 2024 Nov 2;14(21)

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Autographa californica multiple nucleopolyhedrovirus ac106 is required for the nuclear egress of nucleocapsids and intranuclear microvesicle formation.

Mo M, Chen J, Yang Y, Yu Y, Wu W, Yang K, Yuan M
Journal of virology 2024 Nov 19;98(11):e0113524

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Constructing and validating pan-apoptosis-related features for predicting prognosis and immunotherapy response in hepatocellular carcinoma.

He Y, Wu S, Chen L, Chen W, Zhan X, Li J, Wang B, Gao C, Wu J, Wang Q, Li M, Liu B
Biochemical and biophysical research communications 2024 Nov 19;734:150633

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Chiglitazar ameliorates dehydroepiandrosterone-induced polycystic ovary syndrome in rats.

Zhao F, Cui W, Fang C, Luo Y, Zhang C
Journal of ovarian research 2024 Nov 19;17(1):229

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LncRNA AP001007 protects human renal tubular epithelial HK-2 cells and kidney organoids from LPS-induced injury.

Lin S, Ren Z, Li L, Xia S, Yang R, Ye H
Scientific reports 2024 Nov 19;14(1):28578

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GOS enhances BDNF-mediated mammary gland development in pubertal mice via the gut-brain axis.

Ge Y, Cao Y, Zhang J, Li F, Wang J, Sun M, Liu Y, Long X, Guo W, Liu J, Fu S
NPJ biofilms and microbiomes 2024 Nov 19;10(1):130

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LncRNA GTL2 regulates myoblast proliferation and differentiation via the PKA-CREB pathway in Duolang sheep.

Chen Q, Bao JJ, Zhang HC, Huang C, Zhao Q, Pu YB, Jiang L, Hosseiny A, Ibrahim M, Hussain T, He XH, Ma YH, Zhao QJ
Zoological research 2024 Nov 18;45(6):1261-1275

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Angiotensin II Induces Vascular Endothelial Dysfunction by Promoting Lipid Peroxidation-Mediated Ferroptosis via CD36.

Zhou Q, Zhang Y, Shi W, Lu L, Wei J, Wang J, Zhang H, Pu Y, Yin L
Biomolecules 2024 Nov 17;14(11)

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Chamomile Tincture and Lidocaine Hydrochloride Gel Ameliorates Periodontitis: A Preclinical Study.

Sun J, Wang H, Xiao J, Yang Q, Liu H, Yang Z, Liu Y, Huang X, Yang L, Ma L, Cao Z
Biomedicines 2024 Nov 17;12(11)

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Huperzine A protected against ferroptosis via activating PI3K/Akt signaling in lipopolysaccharide induced acute lung injury.

Shi J, Chen W, Tang J, Zhang C, Qi M, Zheng X, Wang J, Liu Q, Liu L, Chen X, Han Z
European journal of pharmacology 2024 Nov 15;983:177004

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NVP-BHG712 alleviates ovariectomy-induced osteoporosis by modulating osteoclastogenesis.

Liu X, Liu S, Sun H, Zhang J, Li M, Shi Y, Wang G, Chen W, Cao Y, Lu G, Ning Y, Zhao Y
European journal of pharmacology 2024 Nov 15;983:177000

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β-Hydroxybutyrate alleviates brain aging through the MTA1 pathway in D-galactose injured mice.

Wang R, Yang X, Wang L, Wang R, Zhang W, Ji Y, Li Z, Li H, Cui L
European journal of pharmacology 2024 Nov 15;983:176959

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Compound (E)-2-(3,4-dihydroxystyryl)-3-hydroxy-4H-pyran-4-one downregulation of Galectin-3 ameliorates Aβ pathogenesis-induced neuroinflammation in 5 × FAD mice.

Liu X, Chen P, Wu W, Zhong M, Dong S, Lin H, Dai C, Zhang Z, Lin S, Che C, Xu J, Li C, Li H, Pan X, Chen Z, Chen X, Ye ZC
Life sciences 2024 Nov 15;357:123085

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Jiawei Bai-Hu-decoction ameliorated heat stroke-induced brain injury by inhibiting TLR4/NF-κB signal and mitophagy of glial cell.

Lin YK, Hong YL, Liu CY, Lin WQ, Liang K, Deng SQ, Zhang XJ, Zeng JX, Wang S
Journal of ethnopharmacology 2024 Nov 15;334:118571

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Astragaloside IV promotes cerebral tissue restoration through activating AMPK- mediated microglia polarization in ischemic stroke rats.

Li MC, Jia JT, Wang YX, Zhuang YM, Wang HY, Lin ZY, Lu Y, Li MZ, Wang ZJ, Zhao H
Journal of ethnopharmacology 2024 Nov 15;334:118532

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Protein profile of mouse endolymph suggests a role in controlling cochlear homeostasis.

Fukuda M, Okanishi H, Ino D, Ono K, Ota T, Wakai E, Sato T, Ohta Y, Kikkawa Y, Inohara H, Kanai Y, Hibino H
iScience 2024 Nov 15;27(11):111214

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SIRT3 differentially regulates lysine benzoylation from SIRT2 in mammalian cells.

Peng P, Lu Y, Ren X, Yan C, Guo X, Liu R, Song X, Huang H
iScience 2024 Nov 15;27(11):111176

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Systematic analysis of lysine lactylation in nucleus pulposus cells.

Sheng L, Xu H, Wang Y, Ni J, Xiang T, Xu H, Zhou X, Wei K, Dai J
iScience 2024 Nov 15;27(11):111157

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Hepatitis B Virus Increases SphK1-S1P Synthesis by Promoting the Availability of the Transcription Factor USF1.

Zhang L, Song YH, Liu J, Zhao YX, Zhou RR, Xu JC, He J, Lu YL, Gan WJ, Lu XS, Li M, Zhou P, Wang L, Han QZ
Journal of immunology (Baltimore, Md. : 1950) 2024 Nov 15;213(10):1499-1507

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Carvacrol alleviates LPS-induced myocardial dysfunction by inhibiting the TLR4/MyD88/NF-κB and NLRP3 inflammasome in cardiomyocytes.

Xu L, Yang X, Liu XT, Li XY, Zhu HZ, Xie YH, Wang SW, Li Y, Zhao Y
Journal of inflammation (London, England) 2024 Nov 15;21(1):47

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SPIN1 accelerates tumorigenesis and confers radioresistance in non-small cell lung cancer by orchestrating the FOXO3a/FOXM1 axis.

Zhong M, Fang Z, Zou J, Chen X, Qiu Z, Zhou L, Le Y, Chen Z, Liao Y, Nie F, Wei X, Zhan J, Xiong J, Xiang X, Fang Z
Cell death & disease 2024 Nov 15;15(11):832

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Granulocyte colony-stimulating factor mediates bone loss via the activation of IL-1β/JNK signaling pathway in murine Staphylococcus aureus-induced osteomyelitis.

Song M, Deng M, Peng Z, Dai F, Wang Y, Shu W, Zhou X, Zhang J, Hou Y, Yu B
International immunopharmacology 2024 Nov 15;141:112959

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SHANK2-AS3: A potential biomarker for Parkinson's disease and its role in neuronal apoptosis via NF-κB signaling in SH-SY5Y cells.

Huang Q, Qin D, Chen C, Kang Y, Chen H, Xu M, Fu R, Dong X
Heliyon 2024 Nov 15;10(21):e38822

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Downregulation of miR-214 promotes dilated Cardiomyopathy Progression through PDE5A-Mediated cGMP regulation.

Yan J, Wang X, Cao P, Li Q, Wu H
Scientific reports 2024 Nov 14;14(1):28070

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A novel mutation in SMARCB1 associated with adult Coffin-Siris syndrome and meningioma.

Guo Z, Bai J, Liu Y, Zhang X, Yang W, Wang J, Zhang Y, Xiao H, Hao B, Liao S
Acta biochimica et biophysica Sinica 2024 Nov 13;57(6):1020-1028

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Periplaneta americana L. extract exerts neuroprotective effects by inhibiting endoplasmic reticulum stress via AKT-dependent pathway in experimental models of Parkinson's disease.

Cao T, Wang XL, Rao JY, Zhu HF, Qi HY, Tian Z
Chinese medicine 2024 Nov 13;19(1):157

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Long-term swimming exercise attenuates right ventricular hypertrophy via modulating meta-inflammation in monocrotaline-induced pulmonary hypertensive rats.

Chen Z, Wang J, Qin X, Di N, Deng H, Li X
Biochemical and biophysical research communications 2024 Nov 12;733:150710

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Triggered Cascade-Activation Nanoplatform to Alleviate Hypoxia for Effective Tumor Immunotherapy Guided by NIR-II Imaging.

Ji Y, Qu S, Shi G, Fan L, Qian J, Sun Z, Lu F, Han X
ACS nano 2024 Nov 12;18(45):31421-31434

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Actin Dysregulation Induces Neuroendocrine Plasticity and Immune Evasion: A Vulnerability of Small Cell Lung Cancer.

Seo Y, Zhang S, Jang J, Ko KP, Kim KB, Huang Y, Kim DW, Kim B, Zou G, Zhang J, Jun S, Chu W, Kirk NA, Hwang YE, Ban YH, Dhar SS, Chan JM, Lee MG, Rudin CM, Park KS, Park JI
bioRxiv : the preprint server for biology 2024 Nov 12;

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NAT10 promotes liver lipogenesis in mouse through N4-acetylcytidine modification of Srebf1 and Scap mRNA.

Wang Z, Wan X, Khan MA, Peng L, Sun X, Yi X, Chen K
Lipids in health and disease 2024 Nov 11;23(1):368

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G protein-coupled receptor 91 activations suppressed mineralization in Porphyromonas gingivalis-infected osteoblasts.

Su W, Zhang D, Wang Y, Lei L, Li H
Scientific reports 2024 Nov 11;14(1):27606

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A tumor-promotional molecular axis CircMAPKBP1/miR-17-3p/TGFβ2 activates autophagy pathway to drive tongue squamous cell carcinoma cisplatin chemoresistance.

Xie S, Li Y, Mai L, Gao X, Huang G, Sun W, Qiao L, Li B, Wang Y, Lin Z
Cancer letters 2024 Nov 1;604:217230

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RNA-binding motif protein 28 enhances angiogenesis by improving STAT3 translation in hepatocellular carcinoma.

Han H, Yuan Y, Li C, Liu L, Yu H, Han G, Wang Q, Lin M, Huang J
Cancer letters 2024 Nov 1;604:217191

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Tanshinone IIA potentiates the therapeutic efficacy of glucocorticoids in lipopolysaccharide-treated HEI-OC1 cells through modulation of the FOXP3/Nrf2 signaling pathway.

Li J, Zhu X, Ye S, Dong Q, Hou J, Liu J, She W
Acta biochimica et biophysica Sinica 2024 Nov 1;57(5):727-737

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Activation of astrocytic NMDA receptors counteracted Aβ-induced reduction of BDNF and elevation of GFAP and complement 3 in the hippocampal astrocytes.

Liu S, Du X, Chen Z, Zhou R, Wang H, Mao X, Du J, Zhang G, Li H, Song Y, Chang L, Wu Y
Neuroscience 2024 Nov 1;559:303-315

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HACE1 exerts a neuroprotective role against oxidative stress in cerebral ischemia-reperfusion injury by activating the PI3K/AKT/Nrf2 pathway.

Zhang X, Wang X, Yin L, Wang D, Jiao H, Liu X, Zheng J
Neuroscience 2024 Nov 1;559:249-262

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NLRX1 and STING alleviate renal ischemia-reperfusion injury by regulating LC3 lipidation during mitophagy.

Liao Y, Li P, Hang Q, Chong Y, Long W, Wei X, Sun D, Liu Y
Experimental cell research 2024 Nov 1;443(1):114323

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Protease activated receptor 2 deficiency retards progression of abdominal aortic aneurysms by modulating phenotypic transformation of vascular smooth muscle cells via ERK signaling.

Wang M, Tang Z, Zeng H, Zhang A, Huang S, Ke J, Gao L, Zhang T, Wang Y, Chang ACY, Zhang J, Chen Q, Gu J, Wang C
Experimental cell research 2024 Nov 1;443(1):114286

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Treatment of Parkinson's disease model with human umbilical cord mesenchymal stem cell-derived exosomes loaded with BDNF.

Wang CC, Hu XM, Long YF, Huang HR, He Y, Xu ZR, Qi ZQ
Life sciences 2024 Nov 1;356:123014

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RNA-binding protein LSM7 facilitates breast cancer metastasis through mediating alternative splicing of CD44.

Li C, Zhang Y, Wang Y, Ouyang J, Yang Y, Zhu Q, Lu Y, Kang T, Li Y, Xia M, Chen J, Li Q, Zhu C, Ye L
Life sciences 2024 Nov 1;356:123013

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Inhibition of HIF-2α expression in cardiomyocytes attenuates PCB126-induced cardiotoxicity associated with decreased apoptosis through the PI3K/Akt and p53 signaling pathways.

Chen L, Chen LJ, Shen HW, Hsu C, Zeng JH, Li JH, Liu JL, Yang JZ, Liu Y, Li XW, Xie XL, Wang Q, Zhao D
Ecotoxicology and environmental safety 2024 Nov 1;286:117185

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2-Ethylhexyl diphenyl phosphate aggravates colitis-induced neuroinflammation and behavioral abnormalities by inhibiting the PI3K-AKT-NF-κB and Wnt/GSK3β signaling pathways.

Hsu C, Zeng JH, Chen L, Chen LJ, Li XW, Yang JZ, Liu Y, Liu JL, Li JH, Li JH, Xie XL, Wang Q
Ecotoxicology and environmental safety 2024 Nov 1;286:117173

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Upregulated DNMT3a coupling with inhibiting p62-dependent autophagy contributes to NNK tumorigenicity in human bronchial epithelial cells.

Liu X, Wang J, Yang Z, Xie Q, Diao X, Yao X, Huang S, Chen R, Zhao Y, Li T, Jiang M, Lou Z, Huang C
Ecotoxicology and environmental safety 2024 Nov 1;286:117157

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Epithelial Piezo1 deletion ameliorates intestinal barrier damage by regulating ferroptosis in ulcerative colitis.

Zhu J, Wu Y, Zhang L, Bai B, Han W, Wang H, Mei Q
Free radical biology & medicine 2024 Nov 1;224:272-286

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Prohibitin 2 confers NADPH oxidase 1-mediated cytosolic oxidative signaling to promote gastric cancer progression by ERK activation.

Xu L, Meng L, Xiang W, Wang X, Yang J, Shu C, Zhao XH, Rong Z, Ye Y
Free radical biology & medicine 2024 Nov 1;224:130-143

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Activation of autophagy by Citri Reticulatae Semen extract ameliorates amyloid-beta-induced cell death and cognition deficits in Alzheimer's disease.

Tang Y, Wei J, Wang XF, Long T, Xiang X, Qu L, Wang X, Yu C, Xiao X, Hu X, Zeng J, Xu Q, Wu A, Wu J, Qin D, Zhou X, Law BY
Neural regeneration research 2024 Nov 1;19(11):2467-2479

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Autophagy mediates the impact of Porphyromonas gingivalis on short-chain fatty acids metabolism in periodontitis-induced gut dysbiosis.

Sun J, Wang X, Xiao J, Yang Q, Huang X, Yang Z, Liu H, Liu Y, Wang H, Huang Z, Ma L, Cao Z
Scientific reports 2024 Nov 1;14(1):26291

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DTL promotes the growth and migration of melanoma cells through the ERK/E2F1/BUB1 axis.

Xuan X, Cao J, Chen L, Zhang J, Qian Y, Huang C
Scientific reports 2024 Nov 1;14(1):26288

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Egfl6 promotes ovarian cancer progression by enhancing the immunosuppressive functions of tumor-associated myeloid cells.

Hamze Sinno S, Imperatore JA, Bai S, Gomes-Jourdan N, Mafarachisi N, Coronnello C, Zhang L, Jašarević E, Osmanbeyoglu HU, Buckanovich RJ, Cascio S
The Journal of clinical investigation 2024 Nov 1;134(21)

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Gas6/AXL Alleviates Hepatic Ischemia/Reperfusion Injury by Inhibiting Ferroptosis via the PI3K/AKT Pathway.

Zhan M, Liu D, Yao L, Wang W, Zhang R, Xu Y, Wang Z, Yan Q, Fang Q, Du J, Chen L
Transplantation 2024 Nov 1;108(11):e357-e369

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Defective Neurogenesis in Lowe Syndrome is Caused by Mitochondria Loss and Cilia-related Sonic Hedgehog Defects.

Lo CH, Chen S, Zhao J, Liu Z, Wang B, Wang Q, Kowal TJ, Sun Y
bioRxiv : the preprint server for biology 2024 Nov 1;

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Autophagy-related protein 5 (ATG5) interacts with bone marrow stromal cell antigen 2 (BST2) to stimulate HBV replication through antagonizing the antiviral activity of BST2.

Li Q, Wen W, Wang Y, Gong T, Wang X, Tan Q, Fan B, Xie H, Li Y, Li S, Yang C, Zhou Z, Duan X, Lin W, Chen L
Journal of medical virology 2024 May;96(5):e29659

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The association between endothelial function and autoimmune thyroiditis induced by iodine excess.

Wang D, Li P, Zhou Z, Jin M, Li B, Li F, Shen H
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2024 May;83:127413

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Excessive linoleic acid induces muscle oxidative stress through 5-lipoxygenase-dependent peroxidation.

Cao X, Guo H, Dai Y, Jiang G, Liu W, Li X, Zhang D, Huang Y, Wang X, Hua H, Wang J, Chen K, Chi C, Liu H
Redox biology 2024 May;71:103096

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Berberine inhibits excessive autophagy and protects myocardium against ischemia/reperfusion injury via the RhoE/AMPK pathway.

Hu F, Hu T, Qiao Y, Huang H, Zhang Z, Huang W, Liu J, Lai S
International journal of molecular medicine 2024 May;53(5)

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Butyrate increases methylglyoxal production through regulation of the JAK2/Stat3/Nrf2/Glo1 pathway in castration‑resistant prostate cancer cells.

Hsia YJ, Lin ZM, Zhang T, Chou TC
Oncology reports 2024 May;51(5)

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Targeting Large-Conductance Calcium-Activated Potassium Channels to Ameliorate Lipopolysaccharide-Induced Depressive-Like Behavior in Mice.

Li G, Hu L, Gu X, Zhu W, Zhen X, Sun X
Neurochemical research 2024 May;49(5):1239-1253

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Duloxetine protected indomethacin-induced gastric mucosal injury by increasing serotonin-dependent RANTES expression and activating PI3K-AKT-VEGF pathway.

Ding H, Wang Y, Gao Y, Ye F, Yao K, Cao L, Liu Z, Wang G, Zhang J
Toxicology and applied pharmacology 2024 May;486:116950

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20(S)-ginsenoside Rh2 ameliorates ATRA resistance in APL by modulating lactylation-driven METTL3.

Cheng S, Chen L, Ying J, Wang Y, Jiang W, Zhang Q, Zhang H, Wang J, Wang C, Wu H, Ye J, Zhang L
Journal of ginseng research 2024 May;48(3):298-309

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Macrophages promote the transition from myocardial ischemia reperfusion injury to cardiac fibrosis in mice through GMCSF/CCL2/CCR2 and phenotype switching.

Shen SC, Xu J, Cheng C, Xiang XJ, Hong BY, Zhang M, Gong C, Ma LK
Acta pharmacologica Sinica 2024 May;45(5):959-974

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Mangiferin alleviates diabetic pulmonary fibrosis in mice via inhibiting endothelial-mesenchymal transition through AMPK/FoxO3/SIRT3 axis.

Fu TL, Li GR, Li DH, He RY, Liu BH, Xiong R, Xu CZ, Lu ZL, Song CK, Qiu HL, Wang WJ, Zou SS, Yi K, Li N, Geng Q
Acta pharmacologica Sinica 2024 May;45(5):1002-1018

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Characteristics of spatial protein expression in the mouse cochlear sensory epithelia: Implications for age-related hearing loss.

Lao H, Zhu Y, Yang M, Wang L, Tang J, Xiong H
Hearing research 2024 May;446:109006

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Colorectal cancer cells secreting DKK4 transform fibroblasts to promote tumour metastasis.

Li X, Chen Y, Lu R, Hu M, Gu L, Huang Q, Meng W, Zhu H, Fan C, Zhou Z, Mo X
Oncogene 2024 May;43(20):1506-1521

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Molecular mechanism of quercetin in treating RA-ILD based on network pharmacology, molecular docking, and experimental validation.

Wang J, Wang Z, Zhao Y, Bai L, Wei Y, Huang T, Xu Y, Zhou X
Naunyn-Schmiedeberg's archives of pharmacology 2024 May;397(5):3077-3092

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TOPK promotes the development of psoriasis and worenine alleviates psoriasiform dermatitis by inhibiting TOPK activity.

Lu H, Huang Y, Ni X, Ma T, Chang T, Liu M, Li N, Lu P, Yuan P, Liu L, Shi F, Xiao J, Xiao H, Duan Q, Zhu F
Journal of the European Academy of Dermatology and Venereology : JEADV 2024 May;38(5):851-863

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4-PBA exerts brain-protective effects against sepsis-associated encephalopathy in a mouse model of sepsis.

Xiong F, Wang C, Lu J, Bai G, Zhou D, Ling J
Experimental neurology 2024 May;375:114738

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TSG6-Exo@CS/GP Attenuates Endometrium Fibrosis by Inhibiting Macrophage Activation in a Murine IUA Model.

Sun H, Dong J, Fu Z, Lu X, Chen X, Lei H, Xiao X, Chen S, Lu J, Su D, Xiong Y, Fang Z, Mao J, Chen L, Wang X
Advanced materials (Deerfield Beach, Fla.) 2024 May;36(21):e2308921

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SPI1 activates TGF-β1/PI3K/Akt signaling through transcriptional upregulation of FKBP12 to support the mesenchymal phenotype of glioma stem cells.

Song Y, Zhang Y, Wang X, Han X, Shi M, Xu L, Yu J, Zhang L, Han S
Brain pathology (Zurich, Switzerland) 2024 May;34(3):e13217

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Fast freezing inhibits melanin synthesis of melanocytes by modulating the Wnt/β-catenin signalling pathway.

Wu S, Yuan X, Tang Z, Zang K, Wang C, Li Z, Li H, Ye X, Dang Y
Experimental dermatology 2024 May;33(5):e15101

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Human umbilical cord mesenchymal stem cell-derived exosomal miR-214-3p regulates the progression of gallbladder cancer by regulating ACLY/GLUT1.

Liu L, Xiao W, Yang Z, Wang Q, Yi J
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2024 May;33(5):499-510

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Retinoblastoma-associated protein is important for TRIM24-mediated activation of the mTOR signaling pathway through DUSP2 action in prostate cancer.

Ren D, Li W, Zeng R, Liu X, Liang H, Xiong W, Yang C, Jin X
Cell death and differentiation 2024 May;31(5):592-604

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Electroacupuncture regulates Rab5a-mediating NGF transduction to improve learning and memory ability in the early stage of AD mice.

Li J, Yang M, Dai Y, Guo X, Ding Y, Li X, Zhang S, Xu W, Chen L, Tao J, Liu W
CNS neuroscience & therapeutics 2024 May;30(5):e14743

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Plasma exosomes impair microglial degradation of α-synuclein through V-ATPase subunit V1G1.

Li Y, Wang Y, Kou L, Yin S, Chi X, Sun Y, Wu J, Jin Z, Zhou Q, Zou W, Wang T, Xia Y
CNS neuroscience & therapeutics 2024 May;30(5):e14738

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Bovine parainfluenza virus type 3 infections induce ER stress-mediated autophagy to facilitate virus replication.

Han Y, Wang C, Bai C, Diao E, Yuan B, Lu K, Dong X, Zhang R, Han B, Liu H, Wang J, Wang X, Xiao S, Yang Z
Veterinary microbiology 2024 May;292:110051

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Epigenetic regulation by KDM5A mediates the effects of prenatal PM(2.5) exposure on hippocampal development and synaptic integrity through the Shh signaling pathway.

Huang J, Song C, Liu Y, Zhang T, Wang T, Liu X, Yu L
Ecotoxicology and environmental safety 2024 May;276:116311

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Icariin‑curcumol promotes ferroptosis in prostate cancer cells through Nrf2/HO‑1 signaling.

Sheng W, Li B, Sun T, Zhu C, Li Y, Xu W
Experimental and therapeutic medicine 2024 May;27(5):232

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SUMOylation of GMFB regulates its stability and function in retinal pigment epithelial cells under hyperglycemia.

Sun W, Wang J, Liu C, Gao F, Ou Q, Tian H, Xu J, Zhang J, Li J, Xu J, Jia S, Zhang J, Xu G, Huang J, Jin C, Lu L
International journal of biological macromolecules 2024 May;268(Pt 2):131678

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Iridoid glycosides from Morinda officinalis induce lysosomal biogenesis and promote autophagic flux to attenuate oxidative stress.

Wang YY, Ni JC, Zhao YQ, Yang X, Niu ZP, Yang XZ, Dong XX, Zhao YH, Hao XJ, Ding X
Journal of Asian natural products research 2024 May;26(5):562-574

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Circular RNA hsa_circ_0094976 modulates GPR155 to inhibit gastric adenocarcinoma malignant characteristics by targeting miR-223-3p.

Liu L, Li X, Song L, Yang Y, Li B
Pathology, research and practice 2024 May;257:155325

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TGF-β1 inhibitor P144 protects against benign restenosis after esophageal stenting through TGF-β1/Smads signaling pathway inhibition.

Wu JZ, Zhou C, Liu S, Zhang JX, Yang W, Shi HB, Zhou WZ
Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology 2024 May;25(2):214-222

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Identifying cellular RNA-binding proteins during infection uncovers a role for MKRN2 in influenza mRNA trafficking.

Bonazza S, Coutts HL, Sukumar S, Turkington HL, Courtney DG
PLoS pathogens 2024 May;20(5):e1012231

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Chemical proteomics reveals the target landscape of 1,000 kinase inhibitors.

Reinecke M, Brear P, Vornholz L, Berger BT, Seefried F, Wilhelm S, Samaras P, Gyenis L, Litchfield DW, Médard G, Müller S, Ruland J, Hyvönen M, Wilhelm M, Kuster B
Nature chemical biology 2024 May;20(5):577-585

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TRIM22 facilitates autophagosome-lysosome fusion by mediating the association of GABARAPs and PLEKHM1.

Heo H, Park H, Lee MS, Kim J, Kim J, Jung SY, Kim SK, Lee S, Chang J
Autophagy 2024 May;20(5):1098-1113

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Endorepellin downregulation promotes angiogenesis after experimental traumatic brain injury.

Zhang Q, Jing Y, Gong Q, Cai L, Wang R, Yang D, Wang L, Qu M, Chen H, Tang Y, Tian H, Ding J, Xu Z
Neural regeneration research 2024 May;19(5):1092-1097

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Toosendanin induces hepatotoxicity via disrupting LXRα/Lipin1/SREBP1 mediated lipid metabolism.

Chen S, Ni J, Luo L, Lin J, Peng H, Shen F, Huang Z
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 May;187:114631

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Human epididymis protein 4, a novel potential biomarker for diagnostic and prognosis monitoring of lung cancer.

Zhang T, Chu L, Tan W, Ye C, Dong H
The clinical respiratory journal 2024 May;18(5):e13774

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Novel small molecule DMAMCL induces differentiation in rhabdomyosarcoma by downregulating of DLL1.

Li Q, Chen Y, Chen Y, Hua Z, Gong B, Liu Z, Thiele CJ, Li Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116562

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Protective effect of esculentoside A against myocardial infarction via targeting C-X-C motif chemokine receptor 2.

Gao M, Cai Q, Bian Y, Wang Z, Xu L, Peng J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116529

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Upregulation of ATF4 mediates the cellular adaptation to pharmacologic inhibition of amino acid transporter LAT1 in pancreatic ductal adenocarcinoma cells.

Ma Y, Okuda S, Okanishi H, Xu M, Jin C, Endou H, Ohgaki R, Kanai Y
Journal of pharmacological sciences 2024 May;155(1):14-20

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Discovery of a novel small-molecule activator of SIRT3 that inhibits cell proliferation and migration by apoptosis and autophagy-dependent cell death pathways in colorectal cancer.

Mou Y, Chen Y, Fan Z, Ye L, Hu B, Han B, Wang G
Bioorganic chemistry 2024 May;146:107327

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Riboflavin protects against pancreatic cancer metastasis by targeting TGF-β receptor 1.

Zhao J, Liu X, Jin X, Dong T, Gao X, Wang J, Li Y, Ma E
Bioorganic chemistry 2024 May;146:107274

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WTAP-Mediated N6-Methyladenosine of RNAs Facilitate the Pathophysiology of Atopic Dermatitis.

Tan L, Chen X, Yan S, Guo A, Gao L, Zhou L, Zhou Y, Zeng J, Lu J
The Journal of investigative dermatology 2024 May;144(5):1058-1070.e4

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Rapid discovery of a novel "green" and natural GST inhibitor for sensitizing hepatocellular carcinoma to Cisplatin by visual screening strategy.

Mao L, Qin Y, Fan J, Yang W, Li B, Cao L, Yuan L, Wang M, Liu B, Wang W
Journal of pharmaceutical analysis 2024 May;14(5):100923

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Urolithin A Hijacks ERK1/2-ULK1 Cascade to Improve CD8(+) T Cell Fitness for Antitumor Immunity.

Ma S, Wu Q, Wu W, Tian Y, Zhang J, Chen C, Sheng X, Zhao F, Ding L, Wang T, Zhao L, Xie Y, Wang Y, Yue X, Wu Z, Wei J, Zhang K, Liang X, Gao L, Wang H, Wang G, Li C, Ma C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(18):e2310065

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20(S)-Protopanaxadiol Exerts Antidepressive Effects in Chronic Corticosterone-Induced Rodent Animal Models as an Activator of Brain-Type Creatine Kinase.

Zhu Z, Cheng Y, Han X, Wang T, Zhang H, Yao Q, Chen F, Gu L, Yang D, Chen L, Zhao Y
Journal of agricultural and food chemistry 2024 May 8;72(18):10376-10390

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COSA-1 mediated pro-crossover complex formation promotes meiotic crossing over in C. elegans.

Yang Y, Wang N, Liu G, Nan W, Wang B, Gartner A, Zhang H, Hong Y
Nucleic acids research 2024 May 8;52(8):4375-4392

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The Species Effect: Differential Sphingosine-1-Phosphate Responses in the Bone in Human Versus Mouse.

Frost K, Lewis JW, Jones SW, Edwards JR, Naylor AJ, McGettrick HM
International journal of molecular sciences 2024 May 8;25(10)

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Iron (II)-based metal-organic framework nanozyme for boosting tumor ferroptosis through inhibiting DNA damage repair and system Xc().

Xue P, Zhuang H, Bai T, Zeng X, Deng J, Shao S, Yan S
Journal of nanobiotechnology 2024 May 8;22(1):228

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Aging-induced tRNA(Glu)-derived fragment impairs glutamate biosynthesis by targeting mitochondrial translation-dependent cristae organization.

Li D, Gao X, Ma X, Wang M, Cheng C, Xue T, Gao F, Shen Y, Zhang J, Liu Q
Cell metabolism 2024 May 7;36(5):1059-1075.e9

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p20BAP31 Induces Autophagy in Colorectal Cancer Cells by Promoting PERK-Mediated ER Stress.

Jiang X, Li G, Zhu B, Yang J, Cui S, Jiang R, Wang B
International journal of molecular sciences 2024 May 7;25(10)

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M2 Microglial Extracellular Vesicles Attenuated Blood-brain Barrier Disruption via MiR-23a-5p in Cerebral Ischemic Mice.

Pan JJ, Qi L, Wang L, Liu C, Song Y, Mamtilahun M, Hu X, Li Y, Chen X, Khan H, Xu Q, Wang Y, Tang Y, Yang GY, Zhang Z
Aging and disease 2024 May 7;15(3):1344-1356

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Metaplastic regeneration in the mouse stomach requires a reactive oxygen species pathway.

Miao ZF, Sun JX, Huang XZ, Bai S, Pang MJ, Li JY, Chen HY, Tong QY, Ye SY, Wang XY, Hu XH, Li JY, Zou JW, Xu W, Yang JH, Lu X, Mills JC, Wang ZN
Developmental cell 2024 May 6;59(9):1175-1191.e7

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OMA1 protease eliminates arrested protein import intermediates upon mitochondrial depolarization.

Krakowczyk M, Lenkiewicz AM, Sitarz T, Malinska D, Borrero M, Mussulini BHM, Linke V, Szczepankiewicz AA, Biazik JM, Wydrych A, Nieznanska H, Serwa RA, Chacinska A, Bragoszewski P
The Journal of cell biology 2024 May 6;223(5)

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Isocitrate dehydrogenase 1 upregulation in urinary extracellular vesicles from proximal tubules of type 2 diabetic rats.

Sei H, Hirade N, Kamiya K, Nakashima F, Yoshitake J, Kano K, Mishiro-Sato E, Kikuchi R, Uchida K, Shibata T
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23688

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Melatonin suppresses atherosclerosis by ferroptosis inhibition via activating NRF2 pathway.

Tao Y, Zhao Q, Lu C, Yong W, Xu M, Wang Z, Leng X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23678

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Metabolic Profile and Lipid Metabolism Phenotype in Mice with Conditional Deletion of Hepatic BMAL1.

Gu W, Li T, Huang Y, Wang R, Zhang L, Chen R, Li R, Liu C
International journal of molecular sciences 2024 May 31;25(11)

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Senegenin Attenuates Pulmonary Fibrosis by Inhibiting Oxidative-Stress-Induced Epithelial Cell Senescence through Activation of the Sirt1/Pgc-1α Signaling Pathway.

Zeng Q, Luo Y, Sang X, Liao M, Wen B, Hu Z, Sun M, Luo Z, Huang X, Liu W, Tang S
Antioxidants (Basel, Switzerland) 2024 May 31;13(6)

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Exercise activates interferon response of the liver via Gpld1 to enhance antiviral innate immunity.

Ren T, He J, Zhang T, Niu A, Yuan Y, Zuo Y, Miao Y, Zhang H, Zang L, Qiao C, Cao X, Yang X, Zheng Z, Xu Y, Wu D, Zheng H
Science advances 2024 May 31;10(22):eadk5011

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Differential gene expression and immune cell infiltration in maedi-visna virus-infected lung tissues.

Shi X, Zhang Y, Chen S, Du X, Zhang P, Duan X, Fang H, Liu S
BMC genomics 2024 May 30;25(1):534

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MiR-31-5p alleviates septic cardiomyopathy by targeting BAP1 to inhibit SLC7A11 deubiquitination and ferroptosis.

Liu Y, Hu N, Ai B, Xia H, Li W
BMC cardiovascular disorders 2024 May 30;24(1):286

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ZAP facilitates NLRP3 inflammasome activation via promoting the oligomerization of NLRP3.

Qin D, Wang C, Yan R, Qin Y, Ying Z, Kong H, Zhao W, Zhang L, Song H
International immunopharmacology 2024 May 30;133:112123

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Hydrogen therapy promotes macrophage polarization to the M2 subtype in radiation lung injury by inhibiting the NF-κB signalling pathway.

Gao X, Niu S, Li L, Zhang X, Cao X, Zhang X, Pan W, Sun M, Zhao G, Zheng X, Song G, Zhang Y
Heliyon 2024 May 30;10(10):e30902

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Serum sSelectin-L is an early specific indicator of radiation injury.

Li S, Zhang W, Zhang H, Fan Y, Jia M, Qi Z, Shen L, He S, Wang Z, Wang Q, Li Y
Heliyon 2024 May 30;10(10):e30527

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SIRT1 maintains bone homeostasis by regulating osteoblast glycolysis through GOT1.

Jin X, Sun X, Ma X, Qin Z, Gao X, Kang X, Li H, Sun H
Cellular and molecular life sciences : CMLS 2024 May 3;81(1):204

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E3 ubiquitin ligase RNF128 negatively regulates the IL-3/STAT5 signaling pathway by facilitating K27-linked polyubiquitination of IL-3Rα.

Yu J, Li J, Shen A, Liu Z, He TS
Cell communication and signaling : CCS 2024 May 3;22(1):254

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The therapeutic effect of a novel GAPDH inhibitor in mouse model of breast cancer and efficacy monitoring by molecular imaging.

Zhang YQ, Zhang W, Kong XT, Hai WX, Guo R, Zhang M, Zhang SL, Li B
Cancer cell international 2024 May 29;24(1):188

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Long non-coding RNA PXN-AS1 promotes glutamine synthetase-mediated chronic myeloid leukemia BCR::ABL1-independent resistance to Imatinib via cell cycle signaling pathway.

Li Y, Yuan S, Zhou Y, Zhou J, Zhang X, Zhang P, Xiao W, Zhang Y, Deng J, Lou S
Cancer cell international 2024 May 29;24(1):186

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Upregulation of rate-limiting enzymes in cholesterol metabolism by PKCδ mediates endothelial apoptosis in diabetic wound healing.

Qin P, Zhou P, Huang Y, Long B, Gao R, Zhang S, Zhu B, Li YQ, Li Q
Cell death discovery 2024 May 29;10(1):263

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ISGylation by HERCs facilitates STING activation.

Qin Y, Wang M, Meng X, Wang M, Jiang H, Gao Y, Li J, Zhao C, Han C, Zhao W, Zheng X
Cell reports 2024 May 28;43(5):114135

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SPAG5 deficiency activates autophagy to reduce atherosclerotic plaque formation in ApoE(-/-) mice.

Guo L, Yuan H, Zhu H, Zhou J, Wan Z, Zhou Y
BMC cardiovascular disorders 2024 May 28;24(1):275

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Inhibitory effects of black phosphorus nanosheets on tumor cell proliferation through downregulation of ADIPOQ and downstream signaling pathways.

Liu D, Zhao Q, Tu Z, Zhang S, Deng S, Xiong Z, Zeng J, Wu F, Zhang X, Xing B
Chemico-biological interactions 2024 May 25;395:110994

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Phosphatidylserine Counteracts the High Stocking Density-Induced Stress Response, Redox Imbalance and Immunosuppression in Fish Megalobrama ambylsephala.

Jiang Y, Liu Z, Zhang L, Liu W, Li H, Li X
Antioxidants (Basel, Switzerland) 2024 May 25;13(6)

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miR-122-5p Promotes Cowshed Particulate Matter2.5-Induced Apoptosis in NR8383 by Targeting COL4A1.

Sun Y, Sun K, Ma Z, Zhang X, Du X, Jia Y, Zhu Y, Inam M, Gao Y, Basang W
Toxics 2024 May 25;12(6)

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Alzheimer's disease risk allele of PICALM causes detrimental lipid droplets in microglia.

Kozlova A, Zhang S, Sudwarts A, Zhang H, Smirnou S, Sun X, Stephenson K, Zhao X, Jamison B, Ponnusamy M, He X, Pang ZP, Sanders AR, Bellen HJ, Thinakaran G, Duan J
Research square 2024 May 24;

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Integrated network pharmacology and experimental validation-based approach to reveal the underlying mechanisms and key material basis of Jinhua Qinggan granules against acute lung injury.

Mi Y, Liang Y, Liu Y, Bai Z, Li N, Tan S, Hou Y
Journal of ethnopharmacology 2024 May 23;326:117920

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Gancao decoction attenuates hepatic necroptosis via activating caspase 8 in cholestatic liver injury.

Zou B, Zhang S, Li F, Weng F, Zhao J, Jin J, Yan D, Xu X, Chen G, Liu C, Yao C, Li Y, Qiu F
Journal of ethnopharmacology 2024 May 23;326:117909

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APC/C-regulated CPT1C promotes tumor progression by upregulating the energy supply and accelerating the G1/S transition.

Zhao H, Cheng X, Yan L, Mi F, Wang W, Hu Y, Liu X, Fan Y, Min Q, Wang Y, Zhang W, Wu Q, Zhan Q
Cell communication and signaling : CCS 2024 May 23;22(1):283

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Reduction of specific enterocytes from loss of intestinal LGR4 improves lipid metabolism in mice.

Liang Y, Luo C, Sun L, Feng T, Yin W, Zhang Y, Mulholland MW, Zhang W, Yin Y
Nature communications 2024 May 23;15(1):4393

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Pacidusin B isolated from Phyllanthus acidus triggers ferroptotic cell death in HT1080 cells.

Zhu G, Luo D, Zhao Y, Xiang Z, Chen C, Li N, Hao X, Ding X, Zhang Y, Zhao Y
Natural products and bioprospecting 2024 May 23;14(1):34

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TRIM65 promotes renal cell carcinoma through ubiquitination and degradation of BTG3.

Zhang Q, Li Y, Zhu Q, Xie T, Xiao Y, Zhang F, Li N, Deng K, Xin H, Huang X
Cell death & disease 2024 May 22;15(5):355

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Combination treatment with ferroptosis and autophagy inducers significantly inhibit the proliferation and migration of oral squamous cell carcinoma.

Zhang L, Li Z, Ma X, Yang W, Hao Y, Zhang L, Piao S
Biochemical and biophysical research communications 2024 May 21;709:149842

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LncRNA TubAR complexes with TUBB4A and TUBA1A to promote microtubule assembly and maintain myelination.

Liang X, Gong M, Wang Z, Wang J, Guo W, Cai A, Yang Z, Liu X, Xu F, Xiong W, Fu C, Wang X
Cell discovery 2024 May 21;10(1):54

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Silent information regulator 2 deficiency exacerbates chronic cold exposure-induced colonic injury and p65 activation in mice.

Guo J, Zhang H, Hu H, Zhao T, Ji H, Ma L, Lu J, Yuan J, Xu B
Gene 2024 May 20;907:148276

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Serine/Arginine-Rich Splicing Factor 7 Knockdown Inhibits Aerobic Glycolysis and Growth in HepG2 Cells by Regulating PKM2 Expression.

Shi W, Yao X, Cao X, Fu Y, Wang Y
Current issues in molecular biology 2024 May 20;46(5):5023-5036

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BAP31 Plays an Essential Role in Mouse B Cell Development via Regulation of BCR Signaling.

Zhao B, An F, Hao Z, Zhang W, Wang B
International journal of molecular sciences 2024 May 2;25(9)

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NGEF is a potential prognostic biomarker and could serve as an indicator for immunotherapy and chemotherapy in lung adenocarcinoma.

Chen X, Zhang T, He YQ, Miao TW, Yin J, Ding Q, Yang M, Chen FY, Zeng HP, Liu J, Zhu Q
BMC pulmonary medicine 2024 May 19;24(1):248

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PCDH17 restricts dendritic spine morphogenesis by regulating ROCK2-dependent control of the actin cytoskeleton, modulating emotional behavior.

Yu L, Zeng F, Fan M, Zhang K, Duan J, Tan Y, Liao P, Wen J, Wang C, Wang M, Yuan J, Pang X, Huang Y, Zhang Y, Li JD, Zhang Z, Hu Z
Zoological research 2024 May 18;45(3):535-550

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PPARγ Antagonists Exhibit Antitumor Effects by Regulating Ferroptosis and Disulfidptosis.

Zhang S, Wang Y, Gu J, Yang Y, Liang J, Wang Y, Ji N, Liu M, Zhang Y, Sun S, Chen Q, Li J
Biomolecules 2024 May 18;14(5)

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KAT6A deficiency impairs cognitive functions through suppressing RSPO2/Wnt signaling in hippocampal CA3.

Liu Y, Fan M, Yang J, Mihaljević L, Chen KH, Ye Y, Sun S, Qiu Z
Science advances 2024 May 17;10(20):eadm9326

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Tumor derived exosomal ENTPD2 impair CD8(+) T cell function in colon cancer through ATP-adenosine metabolism reprogramming.

Shi M, Ye L, Zhao L, He L, Chen J, Zhang J, Su Y, Dong H, Liu J, Liang L, Zheng W, Xiao Y, Liu H, Yang X, Yang Z
Cell communication and signaling : CCS 2024 May 16;22(1):274

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FOXC1 regulates endothelial CD98 (LAT1/4F2hc) expression in retinal angiogenesis and blood-retina barrier formation.

Bhakuni T, Norden PR, Ujiie N, Tan C, Lee SK, Tedeschi T, Hsieh YW, Wang Y, Liu T, Fawzi AA, Kume T
Nature communications 2024 May 16;15(1):4097

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The miR-641-STIM1 and SATB1 axes play important roles in the regulation of the Th17/Treg balance in ITP.

Zhu H, Ruan X, Zhao K, Kuang W, Liu S, Yan W, Fu X, Cheng Z, Li R, Peng H
Scientific reports 2024 May 16;14(1):11243

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Alleviative effects of the parthenolide derivative ACT001 on insulin resistance induced by sodium propionate combined with a high-fat diet and its potential mechanisms.

Yu Q, Zuo X, Bai H, Zhang S, Luan J, Zhao Q, Zhao X, Feng X
European journal of pharmacology 2024 May 15;971:176529

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Pyroptosis inhibitors MCC950 and VX-765 mitigate myocardial injury by alleviating oxidative stress, inflammation, and apoptosis in acute myocardial hypoxia.

Ye X, Lin ZJ, Hong GH, Wang ZM, Dou RT, Lin JY, Xie JH, Shen YW
Experimental cell research 2024 May 15;438(2):114061

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Caspase-3/Gasdermin E-mediated pyroptosis contributes to Ricin toxin-induced inflammation.

Xu Y, Dong M, Sun C, Wang Y, Zhao N, Yu K, Lu N, Xu N, Liu W, Wu C
Toxicology letters 2024 May 15;396:19-27

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Wine- and stir-frying processing of Cuscutae Semen enhance its ability to alleviate oxidative stress and apoptosis via the Keap 1-Nrf2/HO-1 and PI3K/AKT pathways in H(2)O(2)-challenged KGN human granulosa cell line.

Liang Y, Shi Y, Guo R, Xu C, Fu M, Shen J, Gao X, Li W, Qin K
BMC complementary medicine and therapies 2024 May 15;24(1):189

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iTRAQ-based proteomic study on monocyte cell model discovered an association of LAMP2 downregulation with HIV-1 latency.

Yin L, Wang Q, Liu S, Chen J, Zhang Y, Lu L, Lu H, Song Z, Zhang L
Proteome science 2024 May 15;22(1):6

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Epigenetic silencing schlafen-11 sensitizes esophageal cancer to ATM inhibitor.

Zhou J, Zhang MY, Gao AA, Zhu C, He T, Herman JG, Guo MZ
World journal of gastrointestinal oncology 2024 May 15;16(5):2060-2073

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Mecp2 fine-tunes quiescence exit by targeting nuclear receptors.

Yang J, Zou S, Qiu Z, Lai M, Long Q, Chen H, Lai PL, Zhang S, Rao Z, Xie X, Gong Y, Liu A, Li M, Bai X
eLife 2024 May 15;12

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Synergistic peptide combinations designed to suppress SARS-CoV-2.

Han T, Song L, Niu X, Qiu M, Wang Y, Wang J, Sun X, Ma J, Hu S, Feng Z
Heliyon 2024 May 15;10(9):e30489

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Dihydroquercetin regulates HIF-1α/AKT/NR2B signalling to improve impaired brain function in rats with metabolic syndrome.

Fu Y, Yuan P, Zeng M, Zhang Q, Hou Y, Gao L, Wei Y, Zheng Y, Feng W, Zheng X
Heliyon 2024 May 15;10(9):e29807

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Pseudorabies virus usurps non-muscle myosin heavy chain IIA to dampen viral DNA recognition by cGAS for antagonism of host antiviral innate immunity.

Liu Y, Qin Y, Yang B, Zheng H, Qiao S, Luo Z, Li R
Journal of virology 2024 May 14;98(5):e0048324

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Novel mutation N588 residue in the NS1 protein of feline parvovirus greatly augments viral replication.

Li L, Liu Z, Liang R, Yang M, Yan Y, Jiao Y, Jiao Z, Hu X, Li M, Shen Z, Peng G
Journal of virology 2024 May 14;98(5):e0009324

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Constraint-Induced Movement Therapy Modulates Neuron Recruitment and Neurotransmission Homeostasis of the Contralesional Cortex to Enhance Function Recovery after Ischemic Stroke.

Zhang A, Xing Y, Zheng J, Li C, Hua Y, Hu J, Tian Z, Bai Y
ACS omega 2024 May 14;9(19):21612-21625

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A Luciferase Immunosorbent Assay Based on Attachment Glycoprotein for the Rapid and Easy Detection of Nipah Virus IgG Antibodies.

Li X, Fang Y, Huang X, Zhao Y, Wan C
Microorganisms 2024 May 14;12(5)

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Epigenetic silencing of LDHB promotes hepatocellular carcinoma by remodeling the tumor microenvironment.

Zhang P, Wan Y, Ma J, Gong J, Zhong Z, Cui Y, Zhang H, Da Y, Ma J, Li C, Liu L, Gong T, Tan Y, Zhang C
Cancer immunology, immunotherapy : CII 2024 May 13;73(7):127

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The crosstalk between macrophages and cancer cells potentiates pancreatic cancer cachexia.

Liu M, Ren Y, Zhou Z, Yang J, Shi X, Cai Y, Arreola AX, Luo W, Fung KM, Xu C, Nipp RD, Bronze MS, Zheng L, Li YP, Houchen CW, Zhang Y, Li M
Cancer cell 2024 May 13;42(5):885-903.e4

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Iron promotes ovarian cancer malignancy and advances platinum resistance by enhancing DNA repair via FTH1/FTL/POLQ/RAD51 axis.

Zhang Q, Chen C, Zou X, Wu W, Di Y, Li N, Fu A
Cell death & disease 2024 May 13;15(5):329

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MSC-derived exosomal miR-140-3p improves cognitive dysfunction in sepsis-associated encephalopathy by HMGB1 and S-lactoylglutathione metabolism.

Ma Y, She X, Liu Y, Qin X
Communications biology 2024 May 11;7(1):562

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Cepharanthine synergistically promotes methylprednisolone pharmacodynamics against human peripheral blood mononuclear cells possibly via regulation of P-glycoprotein/glucocorticoid receptor translocation.

Xu W, Chen S, Wang X, Min J, Tanaka S, Onda K, Sugiyama K, Yamada H, Hirano T
BMC complementary medicine and therapies 2024 May 11;24(1):186

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Glycosides of Buyang Huanwu decoction inhibits inflammation associated with cerebral ischemia-reperfusion via the PINK1/Parkin mitophagy pathway.

Jiao K, Lai Z, Cheng Q, Yang Z, Liao W, Liao Y, Long H, Sun R, Lang T, Shao L, Deng C, She Y
Journal of ethnopharmacology 2024 May 10;325:117766

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Helicobacter pylori disrupts gastric mucosal homeostasis by stimulating macrophages to secrete CCL3.

Wei YF, Li X, Zhao MR, Liu S, Min L, Zhu ST, Zhang ST, Xie SA
Cell communication and signaling : CCS 2024 May 10;22(1):263

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Pan-cancer analysis of LRRC59 with a focus on prognostic and immunological roles in hepatocellular carcinoma.

Pan B, Cheng J, Tan W, Wu X, Fan Q, Fan L, Jiang M, Yu R, Cheng X, Deng Y
Aging 2024 May 10;16(9):8171-8197

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Lycopene Promotes Osteogenesis and Reduces Adipogenesis through Regulating FoxO1/PPARγ Signaling in Ovariectomized Rats and Bone Marrow Mesenchymal Stem Cells.

Xia B, Dai X, Shi H, Yin J, Xu T, Liu T, Yue G, Guo H, Liang R, Liu Y, Gao J, Wang X, Chen X, Tang J, Wang L, Zhu R, Zhang D
Nutrients 2024 May 10;16(10)

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Targeting BRD4 with PROTAC degrader ameliorates LPS-induced acute lung injury by inhibiting M1 alveolar macrophage polarization.

Li D, Deng Y, Wen G, Wang L, Shi X, Chen S, Chen R
International immunopharmacology 2024 May 10;132:111991

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The E3 ubiquitin ligase TRIM9 regulates synaptic function and actin dynamics in response to netrin-1.

McCormick LE, Evans EB, Barker NK, Herring LE, Diering GH, Gupton SL
Molecular biology of the cell 2024 May 1;35(5):ar67

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Inhibition of Gpx4-mediated ferroptosis alleviates cisplatin-induced hearing loss in C57BL/6 mice.

Liu Z, Zhang H, Hong G, Bi X, Hu J, Zhang T, An Y, Guo N, Dong F, Xiao Y, Li W, Zhao X, Chu B, Guo S, Zhang X, Chai R, Fu X
Molecular therapy : the journal of the American Society of Gene Therapy 2024 May 1;32(5):1387-1406

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Tbl1 promotes Wnt-β-catenin signaling-induced degradation of the Tcf7l1 protein in mouse embryonic stem cells.

Yu Y, Liu L, Cao J, Huang R, Duan Q, Ye SD
Journal of cell science 2024 May 1;137(9)

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The role of the sensory input intervention in recovery of the motor function in hypoxic ischemic encephalopathy rat model.

Dong J, Dong Y, An L, Wang Y, Li Y, Jin L
Journal of neurophysiology 2024 May 1;131(5):865-871

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Lrg1 silencing attenuates ischemia-reperfusion renal injury by regulating autophagy and apoptosis through the TGFβ1- Smad1/5 signaling pathway.

Chen J, Zhang Z, Feng L, Liu W, Wang X, Chen H, Zou H
Archives of biochemistry and biophysics 2024 Mar;753:109892

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Myelin repair of spinal cord injury in adult mice induced by treadmill training upregulated peroxisome proliferator-activated receptor gamma coactivator 1 alpha.

Su H, Luo H, Wang Y, Zhao Q, Zhang Q, Zhu Y, Pan L, Liu Y, Yang C, Yin Y, Tan B
Glia 2024 Mar;72(3):607-624

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Knockdown of SIK3 in the CA1 Region can Reduce Seizure Susceptibility in Mice by Inhibiting Decreases in GABA(A)R α1 Expression.

Jiang ZF, Xuan LN, Sun XW, Liu SB, Yin J
Molecular neurobiology 2024 Mar;61(3):1404-1416

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Involvement of DJ-1 in the pathogenesis of intervertebral disc degeneration via hexokinase 2-mediated mitophagy.

Lin J, Wang L, Wu Y, Xiang Q, Zhao Y, Zheng X, Jiang S, Sun Z, Fan D, Li W
Experimental & molecular medicine 2024 Mar;56(3):747-759

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Gene expression analysis of oxidative stress-related genes in the apical, middle, and basal turns of the cochlea.

Yang Y, Chen X, Tian C, Fan B, An X, Liu Z, Li Q, Mi W, Lin Y, Zha D
Gene expression patterns : GEP 2024 Mar;51:119356

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Morphine induces HADHA succinylation, while HADHA desuccinylation alleviates morphine tolerance by influencing autophagy.

Huang Y, Lu S, Chen Y, Feng Y, Lu W
Naunyn-Schmiedeberg's archives of pharmacology 2024 Mar;397(3):1589-1600

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Lead inhibits microglial cell migration via suppression of store-operated calcium entry.

Tang W, Peng J, Chen L, Yu C, Wang Y, Zou F, Zheng G, Meng X
Toxicology letters 2024 Mar;393:69-77

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Melatonin ameliorates PM2.5-induced spermatogenesis disorder by preserving H3K9 methylation and SIRT3.

Liu J, Zhao M, Dong X, Zhang Y, Xue J, Duan J, Sun Z, Zhou X
Environmental toxicology 2024 Mar;39(3):1471-1480

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Hypothermic machine perfusion reduces donation after circulatory death liver ischemia-reperfusion injury through the SERPINA3-mediated PI3Kδ/Akt pathway.

Peng S, Liang W, Liu Z, Ye S, Peng Z, Zhong Z, Ye Q
Human cell 2024 Mar;37(2):420-434

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Rab5c promotes RSV and ADV replication by autophagy in respiratory epithelial cells.

Wang X, Cheng J, Shen L, Chen M, Sun K, Li J, Li M, Ma C, Wei L
Virus research 2024 Mar;341:199324

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40 Hz light flickering promotes sleep through cortical adenosine signaling.

Zhou X, He Y, Xu T, Wu Z, Guo W, Xu X, Liu Y, Zhang Y, Shang H, Huang L, Yao Z, Li Z, Su L, Li Z, Feng T, Zhang S, Monteiro O, Cunha RA, Huang ZL, Zhang K, Li Y, Cai X, Qu J, Chen JF
Cell research 2024 Mar;34(3):214-231

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Fucoidan suppresses proliferation and epithelial-mesenchymal transition process via Wnt/β-catenin signalling in hemangioma.

Zhu Z, Luo J, Li L, Wang D, Xu Q, Teng J, Zhou J, Sun L, Yu N, Zuo D
Experimental dermatology 2024 Mar;33(3):e15027

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Divergent Roles of KLF4 During Primordial Germ Cell Fate Induction from Human Embryonic Stem Cells.

Fang F, Li Z, Zhang X, Huang Q, Lu S, Wang X
Reproductive sciences (Thousand Oaks, Calif.) 2024 Mar;31(3):727-735

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Lipid overload-induced RTN3 activation leads to cardiac dysfunction by promoting lipid droplet biogenesis.

Guo D, Zhang M, Qi B, Peng T, Liu M, Li Z, Fu F, Guo Y, Li C, Wang Y, Hu L, Li Y
Cell death and differentiation 2024 Mar;31(3):292-308

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Normobaric hyperoxia alleviates complement C3-mediated synaptic pruning and brain injury after intracerebral hemorrhage.

Wu M, Chen K, Zhao Y, Jiang M, Bao B, Yu W, Chen Z, Yin X
CNS neuroscience & therapeutics 2024 Mar;30(3):e14694

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Rasd1 is involved in white matter injury through neuron-oligodendrocyte communication after subarachnoid hemorrhage.

Fu W, Che X, Tan J, Cui S, Ma Y, Xu D, Long H, Yang X, Wen T, He Z
CNS neuroscience & therapeutics 2024 Mar;30(3):e14452

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Inhibition of HDAC6 promotes microvascular endothelial cells to phagocytize myelin debris and reduces inflammatory response to accelerate the repair of spinal cord injury.

Wu C, Pan Y, Wang L, Liu M, Tu P, Chen S, Shi L, Yan D, Ma Y, Guo Y
CNS neuroscience & therapeutics 2024 Mar;30(3):e14439

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CD8(+) T cell infiltration and proliferation in the brainstem during experimental cerebral malaria.

Wang J, Zhu Q, Shen Y, Liang J, Wang Y, Huang Y, Tong G, Wang X, Zhang N, Yu K, Li Y, Zhao Y
CNS neuroscience & therapeutics 2024 Mar;30(3):e14431

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Selective HDAC6 inhibition protects against blood-brain barrier dysfunction after intracerebral hemorrhage.

Peng C, Wang Y, Hu Z, Chen C
CNS neuroscience & therapeutics 2024 Mar;30(3):e14429

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Protective Effects of Danmu Extract Syrup on Acute Lung Injury Induced by Lipopolysaccharide in Mice through Endothelial Barrier Repair.

Xu H, Xu SC, Li LY, Wu YH, Tan YF, Chen L, Liu P, Liang CF, He XN, Li YH
Chinese journal of integrative medicine 2024 Mar;30(3):243-250

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Capnocytophaga gingivalis is a potential tumor promotor in oral cancer.

Zhu W, Shen W, Wang J, Xu Y, Zhai R, Zhang J, Wang M, Wang M, Liu L
Oral diseases 2024 Mar;30(2):353-362

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The construction and immunogenicity analyses of a recombinant pseudorabies virus with Senecavirus A VP3 protein co-expression.

Tao Q, Xu L, Zhang Y, Yang Y, Liu Z, Xu T, Lai S, Ai Y, Zhu L, Xu Z
Veterinary microbiology 2024 Mar;290:110011

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Blockade of BTLA alone or in combination with PD-1 restores the activation and proliferation of CD8(+) T cells during in vitro infection with NCP BVDV.

Liu Y, Zhao Z, Su S, Li Y, Chen N, He L, Dong M, Xu B, Zhang Z, Zhou Y, Zhu Z
Veterinary microbiology 2024 Mar;290:110004

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African swine fever virus maintains de novo global cellular protein synthesis and inhibits stress granules formation via dephosphorylating eIF2α.

Gao H, Gao X, Liu X, Luo Y, Zhong J, Liu J, Yan L, Wang H, Gong L, Zhang G, Zheng Z, Sun Y
Veterinary microbiology 2024 Mar;290:109988

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Bovine parainfluenza type 3 virus induces incomplete autophagy to promote viral replication by activated beclin1 in vitro.

Han Y, Wang C, Lu K, Dong X, Chang Z, Zhang R, Hou Q, Wang X, Xiao S, Liu H, Yang Z
Veterinary microbiology 2024 Mar;290:109972

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A lncRNA Dleu2-encoded peptide relieves autoimmunity by facilitating Smad3-mediated Treg induction.

Tang S, Zhang J, Lou F, Zhou H, Cai X, Wang Z, Sun L, Sun Y, Li X, Fan L, Li Y, Jin X, Deng S, Yin Q, Bai J, Wang H, Wang H
EMBO reports 2024 Mar;25(3):1208-1232

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Alpha-Emitter Radium-223 Induces STING-Dependent Pyroptosis to Trigger Robust Antitumor Immunity.

Yang M, Liu H, Lou J, Zhang J, Zuo C, Zhu M, Zhang X, Yin Y, Zhang Y, Qin S, Zhang H, Fan X, Dang Y, Cheng C, Cheng Z, Yu F
Small (Weinheim an der Bergstrasse, Germany) 2024 Mar;20(9):e2307448

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A genome-wide CRISPR screening uncovers that TOB1 acts as a key host factor for FMDV infection via both IFN and EGFR mediated pathways.

Peng G, Liu T, Qi X, Wang Y, Ren J, Peng J, Du X, Hu S, Wu S, Zhao Y, Li D, Zheng H
PLoS pathogens 2024 Mar;20(3):e1012104

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A preliminary mechanistic exploration of the effect of leptin on the docetaxel sensitivity of MDA‑MB‑231 triple‑negative breast cancer cells.

Gao S, Ding S, Tang Z
Molecular and clinical oncology 2024 Mar;20(3):24

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STING activation in cardiomyocytes drives hypertrophy-associated heart failure via NF-κB-mediated inflammatory response.

Wang L, Zhang S, Liu H, Gao L, He L, Chen Y, Zhang J, Yang M, He C
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):166997

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S100A9(-/-) alleviates LPS-induced acute lung injury by regulating M1 macrophage polarization and inhibiting pyroptosis via the TLR4/MyD88/NFκB signaling axis.

Gong C, Ma J, Deng Y, Liu Q, Zhan Z, Gan H, Xiang X, Zhang M, Cao K, Shen T, Fang L, Shen B, Shen S, Ding S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116233

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Ramelteon alleviates myocardial ischemia/reperfusion injury (MIRI) through Sirt3--dependent regulation of cardiomyocyte apoptosis.

Yang Z, Xie Y, Li M, Chen W, Zhong C, Ju J, Deng Q, Wang H, Cheng T, Zhang L, Du W, Liang H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116229

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Proteomic Characterization Identifies Clinically Relevant Subgroups of Gastrointestinal Stromal Tumors.

Sun M, Tong Y, Yuan W, Wang Y, Pu Y, Huang W, Lv B, Xu C, Jiang W, Luo R, Fang R, Tang S, Ren L, Wang J, Feng J, Sun C, Shen K, He F, Hou Y, Ding C
Gastroenterology 2024 Mar;166(3):450-465.e33

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Inhibition of amino acid transporter LAT1 in cancer cells suppresses G0/G1-S transition by downregulating cyclin D1 via p38 MAPK activation.

Zhou X, Ohgaki R, Jin C, Xu M, Okanishi H, Endou H, Kanai Y
Journal of pharmacological sciences 2024 Mar;154(3):182-191

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TOX3 deficiency mitigates hyperglycemia by suppressing hepatic gluconeogenesis through FoxO1.

Liu C, Zheng Y, Hu S, Liang X, Li Y, Yu Z, Liu Y, Bian Y, Man Y, Zhao S, Liu X, Liu H, Huang T, Ma J, Chen ZJ, Zhao H, Zhang Y
Metabolism: clinical and experimental 2024 Mar;152:155766

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Mucous cell histopathology and label-free quantitative proteomic analysis of skin mucus in fat greenling (Hexagrammos otakii) infected with Vibrio harveyi.

Wei X, Shi Y, Wang S, Liu H, Zhang Z, Yu L, Hua W, Cui D, Chen Y, Li X, Wang W
Fish & shellfish immunology 2024 Mar;146:109398

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Design, synthesis, and pharmacological evaluation of novel benzothiazole derivatives targeting LCK in acute lymphoblastic leukemia.

Chen Y, Zhang K, Tan J, Fan Z, Fu Y, Li X, Liu B, Wang G
Bioorganic chemistry 2024 Mar;144:107180

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Novel compound heterozygous variants in FANCI cause premature ovarian insufficiency.

Cao L, He X, Ren J, Wen C, Guo T, Yang F, Qin Y, Chen ZJ, Zhao S, Yang Y
Human genetics 2024 Mar;143(3):357-369

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Tau induces inflammasome activation and microgliosis through acetylating NLRP3.

Zhang L, Gai Y, Liu Y, Meng D, Zeng Y, Luo Y, Zhang H, Wang Z, Yang M, Li Y, Liu Y, Lai Y, Yang J, Wu G, Chen Y, Zhu J, Liu S, Yu T, Zeng J, Wang J, Zhu D, Wang X, Lan X, Liu R
Clinical and translational medicine 2024 Mar;14(3):e1623

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Hepatic transcriptome discloses the potential targets of Xuefu Zhuyu Decoction ameliorating non-alcoholic fatty liver disease induced by high-fat diet.

Tang H, Wang J, Fang Y, Yin Y, Liu W, Hu Y, Peng J
Journal of traditional and complementary medicine 2024 Mar;14(2):135-147

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FGF19 Promotes the Proliferation and Insulin Secretion from Human Pancreatic β Cells Via the IRS1/GLUT4 Pathway.

Zeng T, Tang X, Bai X, Xiong H
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2024 Mar;132(3):152-161

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The synbiotic combination of probiotics and inulin improves NAFLD though modulating gut microbiota.

Zhang C, Fang T, Shi L, Wang Y, Deng X, Wang J, Zhou Y
The Journal of nutritional biochemistry 2024 Mar;125:109546

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MBIP promotes ESCC metastasis by activating MAPK pathway.

Ma Y, Hua Y, Yin X, Jiao Y, Xu E, Yan T, Yang J, Zhang L
Cellular signalling 2024 Mar;115:111040

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Identification of PRDX5 as A Target for The Treatment of Castration-Resistant Prostate Cancer.

Wang R, Mi Y, Ni J, Wang Y, Ding L, Ran X, Sun Q, Tan SY, Koeffler HP, Feng N, Chen YQ
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(9):e2304939

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Cfp1 Controls Cardiomyocyte Maturation by Modifying Histone H3K4me3 of Structural, Metabolic, and Contractile Related Genes.

Li C, Zhang Y, Shen J, Bao H, Zhao Y, Li D, Li S, Liu Y, Yang J, Zhou Z, Gao K, Zhao L, Pei Y, Lu Y, Pan Z, Cai B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(11):e2305992

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Disrupting PIAS3-mediated SUMOylation of MLK3 ameliorates poststroke neuronal damage and deficits in cognitive and sensorimotor behaviors.

Jiang Y, Hu L, Wang B, Zhang B, Shao M, Meng L, Xu Y, Chen R, Li M, Du C
Cellular and molecular life sciences : CMLS 2024 Mar 8;81(1):119

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Polyphyllin B inhibited STAT3/NCOA4 pathway and restored gut microbiota to ameliorate lung tissue injury in cigarette smoke-induced mice.

Wang Q, He Z, Zhu J, Hu M, Yang L, Yang H
BMC biotechnology 2024 Mar 8;24(1):13

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Aryl hydrocarbon receptor suppresses STING-mediated type I IFN expression in triple-negative breast cancer.

Martin JC, da Silva Fernandes T, Chaudhry KA, Oshi M, Abrams SI, Takabe K, Rosario SR, Bianchi-Smiraglia A
Scientific reports 2024 Mar 8;14(1):5731

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High expression of KIFC1 is a poor prognostic biomarker and correlates with TP53 mutation in lung cancer.

Li X, Wang S, Ruan P, Bajinka O, Zhang W
Medicine 2024 Mar 8;103(10):e37286

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Interleukin-22 Contributes to Blood-Brain Barrier Disruption via STAT3/VEGFA Activation in Escherichia coli Meningitis.

Yang R, Chen J, Qu X, Liu H, Wang X, Tan C, Chen H, Wang X
ACS infectious diseases 2024 Mar 8;10(3):988-999

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Late-stage modification of complex drug: Base-controlled Pd-catalyzed regioselective synthesis and bioactivity of arylated osimertinibs.

Feng R, Zhen YQ, Wu D, Sun L, Xu JB, Li X, Zhang L, Gao F
Science advances 2024 Mar 8;10(10):eadl0026

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Nicotine regulates abnormal macrophage polarization and trophoblast invasion associated with preterm labor via the α7nAChR/SIRT1 axis.

Ye A, Li L, Chen H, Tao P, Lou S
Placenta 2024 Mar 6;147:42-51

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Identified S100A9 as a target for diagnosis and treatment of ulcerative colitis by bioinformatics analysis.

Tan L, Li X, Qin H, Zhang Q, Wang J, Chen T, Zhang C, Zhang X, Tan Y
Scientific reports 2024 Mar 6;14(1):5517

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Hinokitiol protects gastric injury from ethanol exposure via its iron sequestration capacity.

Zhao M, Qiao C, Yang S, Tang Y, Sun W, Sun S, Guo Q, Du F, Zhang N, Ning T, Wu J, Xu J, Li P
European journal of pharmacology 2024 Mar 5;966:176340

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Dietary Restriction Improves Perioperative Neurocognitive Disorders by Inhibiting Neuroinflammation and Gut Microbial Dysbiosis.

Ren L, Liang H, Zhu L, Yang X, Zhang H, Sun N, Huang D, Feng J, Wu Y, Xiong L, Ke X, Li M, Zhang A
Neuroscience 2024 Mar 5;540:48-67

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T-2 toxin induces mitochondrial dysfunction in chondrocytes via the p53-cyclophilin D pathway.

Yu FF, Yu SY, Sun L, Zuo J, Luo KT, Wang M, Fu XL, Zhang F, Huang H, Zhou GY, Wang YJ, Ba Y
Journal of hazardous materials 2024 Mar 5;465:133090

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Augmentation of scleral glycolysis promotes myopia through histone lactylation.

Lin X, Lei Y, Pan M, Hu C, Xie B, Wu W, Su J, Li Y, Tan Y, Wei X, Xue Z, Xu R, Di M, Deng H, Liu S, Yang X, Qu J, Chen W, Zhou X, Zhao F
Cell metabolism 2024 Mar 5;36(3):511-525.e7

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Whole genome sequencing analysis of Limosilactobacillus reuteri from the intestinal tract of mice recovering from ulcerative colitis and preliminary study on anti-inflammatory effects of its derived peptides.

Wang Z, Zhang Z, Shi Q, Liu S, Wu Q, Wang Z, Saiding E, Han J, Zhou J, Wang R, Su X
Archives of microbiology 2024 Mar 5;206(4):140

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SARS-CoV-2 NSP2 as a Potential Delivery Vehicle for Proteins.

Zheng N, Liu S, Chen J, Xu Y, Cao W, Lin J, Lu G, Zhang G
Molecular pharmaceutics 2024 Mar 4;21(3):1149-1159

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CSNK2A1 confers gemcitabine resistance to pancreatic ductal adenocarcinoma via inducing autophagy.

Liu ZD, Shi YH, Xu QC, Zhao GY, Zhu YQ, Li FX, Ma MJ, Ye JY, Huang XT, Wang XY, Xu X, Wang JQ, Zhao W, Yin XY
Cancer letters 2024 Mar 31;585:216640

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WNT2B activates macrophages via NF-κB signaling pathway in inflammatory bowel disease.

Lan L, Huang C, Liu D, Cheng Y, Tang R, Gu J, Geng L, Cheng Y, Gong S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 31;38(6):e23551

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PGRN inhibits CD8(+)T cell recruitment and promotes breast cancer progression by up-regulating ICAM-1 on TAM.

Zhou T, Qian H, Zhang D, Fang W, Yao M, Shi H, Chen T, Chai C, Guo B
Cancer immunology, immunotherapy : CII 2024 Mar 30;73(5):76

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Pcgf5: An important regulatory factor in early embryonic neural induction.

Yang X, Zhou W, Zhou J, Li A, Zhang C, Fang Z, Wang C, Liu S, Hao A, Zhang M
Heliyon 2024 Mar 30;10(6):e27634

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Elucidating the role of intrinsic adenosine A1 receptors in acute alcoholism using human-induced pluripotent stem cell-derived hepatocytes.

Nagata T, Huang YG
Bioscience reports 2024 Mar 29;44(3)

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Grb7 Ablation in Mice Improved Glycemic Control, Enhanced Insulin Signaling, and Increased Abdominal fat Mass in Females.

Vermehren-Schmaedick A, Joshi S, Wagoner W, Norgard MA, Packwood W, Diba P, Mendez H, Fedorov LM, Rakshe S, Park B, Marks DL, Grossberg A, Luoh SW
Endocrinology 2024 Mar 29;165(5)

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Fermented Protaetia brevitarsis Larvae Ameliorates Chronic Ethanol-Induced Hepatotoxicity in Mice via AMPK and TLR-4/TGF-β1 Pathways.

Lee HL, Kim JM, Go MJ, Joo SG, Kim TY, Lee HS, Kim JH, Son JS, Heo HJ
Journal of microbiology and biotechnology 2024 Mar 28;34(3):606-621

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Fisetin Alleviates Inflammation and Oxidative Stress in Deep Vein Thrombosis via MAPK and NRF2 Signaling Pathway.

Liu H, Lu Q
International journal of molecular sciences 2024 Mar 27;25(7)

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The Tumor Microenvironment Mediates the HIF-1α/PD-L1 Pathway to Promote Immune Escape in Colorectal Cancer.

Sun J, Zhao Z, Lu J, An W, Zhang Y, Li W, Yang L
International journal of molecular sciences 2024 Mar 27;25(7)

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Human periodontal ligament stem cell sheets activated by graphene oxide quantum dots repair periodontal bone defects by promoting mitochondrial dynamics dependent osteogenic differentiation.

An N, Yan X, Qiu Q, Zhang Z, Zhang X, Zheng B, Zhao Z, Guo J, Liu Y
Journal of nanobiotechnology 2024 Mar 27;22(1):133

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SRRM2 phase separation drives assembly of nuclear speckle subcompartments.

Zhang M, Gu Z, Guo S, Sun Y, Ma S, Yang S, Guo J, Fang C, Shu L, Ge Y, Chen Z, Wang B
Cell reports 2024 Mar 26;43(3):113827

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Exploring the molecular mechanism of Artemisia rupestris L. for the treatment of hepatocellular carcinoma via PI3K/AKT pathway.

Zhang S, Cai X, Khan GJ, Cheng J, He J, Zhai K, Mao Y
Journal of ethnopharmacology 2024 Mar 25;322:117572

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MiR-155-5p improves the insulin sensitivity of trophoblasts by targeting CEBPB in gestational diabetes mellitus.

Zhang H, Jiang Y, Zhu S, Wei L, Zhou X, Gao P, Zhang J, Chen Y, Du Y, Fang C, Su R, Li J, Wang S, Feng L
Placenta 2024 Mar 25;148:1-11

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A novel microglia-targeting strategy based on nanoparticle-mediated delivery of miR-26a-5p for long-lasting analgesia in chronic pain.

Lu Y, Liu S, Wang P, Guo X, Qin Z, Hou H, Tao T
Journal of nanobiotechnology 2024 Mar 23;22(1):128

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AURKA emerges as a vulnerable target for KEAP1-deficient non-small cell lung cancer by activation of asparagine synthesis.

Deng B, Liu F, Chen N, Li X, Lei J, Chen N, Wu J, Wang X, Lu J, Fang M, Chen A, Zhang Z, He B, Yan M, Zhang Y, Wang Z, Liu Q
Cell death & disease 2024 Mar 23;15(3):233

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Identification and validation of DHCR7 as a diagnostic biomarker involved in the proliferation and mitochondrial function of breast cancer.

Wang Y, Fan J, Liu Y, Du J, Liang B, Wang H, Song Z
Aging 2024 Mar 22;16(7):5967-5986

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G-quadruplexes on chromosomal DNA negatively regulates topoisomerase 1 activity.

Liang HT, Yan JY, Yao HJ, Zhang XN, Xing ZM, Liu L, Chen YQ, Li GR, Huang J, He YD, Zheng KW
Nucleic acids research 2024 Mar 21;52(5):2142-2156

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Trimethylamine N-oxide impairs β-cell function and glucose tolerance.

Kong L, Zhao Q, Jiang X, Hu J, Jiang Q, Sheng L, Peng X, Wang S, Chen Y, Wan Y, Hou S, Liu X, Ma C, Li Y, Quan L, Chen L, Cui B, Li P
Nature communications 2024 Mar 21;15(1):2526

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[Activation of α7 nAChR improves white fat homeostasis and promotes beige adipogenesis and thermogenesis in obese mice].

Bao H, Wang S, Lü M, Wang Y, Jiang P, Li X
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2024 Mar 20;44(3):499-506

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Bi(2)S(3)/Ti(3)C(2)-TPP nano-heterostructures induced by near-infrared for photodynamic therapy combined with photothermal therapy on hypoxic tumors.

Jiang H, Sun J, Liu F, Zhao Y, Chen X, Dai C, Wen Z
Journal of nanobiotechnology 2024 Mar 20;22(1):123

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Identification and validation of a novel signature based on macrophage marker genes for predicting prognosis and drug response in kidney renal clear cell carcinoma by integrated analysis of single cell and bulk RNA sequencing.

Chen X, Zhang Z, Qin Z, Zhu X, Wang K, Kang L, Li C, Wang H
Aging 2024 Mar 20;16(6):5676-5702

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Extracellular vesicles secreted from mesenchymal stem cells ameliorate renal ischemia reperfusion injury by delivering miR-100-5p targeting FKBP5/AKT axis.

Chen G, Li X, Zhou X, Li Y, Yu H, Peng X, Bai X, Zhang C, Feng Z, Mei Y, Li L, Liu Y, Gou X, Jiang Y
Scientific reports 2024 Mar 20;14(1):6720

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Lactobacillus rhamnosus GG ameliorates hyperuricemia in a novel model.

Fu Y, Chen YS, Xia DY, Luo XD, Luo HT, Pan J, Ma WQ, Li JZ, Mo QY, Tu Q, Li MM, Zhao Y, Li Y, Huang YT, Chen ZX, Li ZJ, Bernard L, Dione M, Zhang YM, Miao K, Chen JY, Zhu SS, Ren J, Zhou LJ, Jiang XZ, Chen J, Lin ZP, Chen JP, Ye H, Cao QY, Zhu YW, Yang L, Wang X, Wang WC
NPJ biofilms and microbiomes 2024 Mar 20;10(1):25

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Endogenous TDP-43 mislocalization in a novel knock-in mouse model reveals DNA repair impairment, inflammation, and neuronal senescence.

Mitra J, Dharmalingam P, Kodavati M, Guerrero EN, Rao KS, Garruto RM, Hegde ML
Research square 2024 Mar 20;

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Ubiquitin-specific proteinase 1 stabilizes PRRSV nonstructural protein Nsp1β to promote viral replication by regulating K48 ubiquitination.

Zhai Y, Du Y, Yuan H, Fan S, Chen X, Wang J, He W, Han S, Zhang Y, Hu M, Zhang G, Kong Z, Wan B
Journal of virology 2024 Mar 19;98(3):e0168623

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RBM14 inhibits the replication of porcine epidemic diarrhea virus by recruiting p62 to degrade nucleocapsid protein through the activation of autophagy and interferon pathway.

Wang X, Tong W, Yang X, Zhai H, Qin W, Liu C, Zheng H, Yu H, Tong G, Zhang Z, Kong N, Shan T
Journal of virology 2024 Mar 19;98(3):e0018224

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Deacetylase Sirtuin 1 mitigates type I IFN- and type II IFN-induced signaling and antiviral immunity.

Yu S-S, Tang R-C, Zhang A, Geng S, Yu H, Zhang Y, Sun X-Y, Zhang J
Journal of virology 2024 Mar 19;98(3):e0008824

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ART1 knockdown decreases the IL-6-induced proliferation of colorectal cancer cells.

Lin T, Zhang S, Tang Y, Xiao M, Li M, Gong H, Xie H, Wang Y
BMC cancer 2024 Mar 19;24(1):354

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Pan-cancer analysis of NUP155 and validation of its role in breast cancer cell proliferation, migration, and apoptosis.

Wang ZQ, Wu ZX, Wang ZP, Bao JX, Wu HD, Xu DY, Li HF, Xu YY, Wu RX, Dai XX
BMC cancer 2024 Mar 19;24(1):353

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CircALMS1 Alleviates Pulmonary Microvascular Endothelial Cell Dysfunction in Pulmonary Hypertension.

Hu X, Sun Y, Wang S, Zhao H, Wei Y, Fu J, Huang Y, Wu W, Li J, Liu J, Gong S, Zhao Q, Wang L, Jiang R, Song X, Yuan P
Journal of the American Heart Association 2024 Mar 19;13(6):e031867

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Loss of Preproinsulin Interaction with Signal Recognition Particle Activates Protein Quality Control, Decreasing mRNA Stability.

Miller SC, Tikhonova EB, Hernandez SM, Dufour JM, Karamyshev AL
Journal of molecular biology 2024 Mar 15;436(6):168492

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Co-exposure to polystyrene nanoplastics and triclosan induces synergistic cytotoxicity in human KGN granulosa cells by promoting reactive oxygen species accumulation.

Wang W, Zhou C, Ma Z, Zeng L, Wang H, Cheng X, Zhang C, Xue Y, Yuan Y, Li J, Hu L, Huang J, Luo T, Zheng L
Ecotoxicology and environmental safety 2024 Mar 15;273:116121

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TET2 stabilized by deubiquitinase USP21 ameliorates cigarette smoke-induced apoptosis in airway epithelial cells.

Luo L, Zeng Z, Li T, Liu X, Cui Y, Tao Y, Li Y, Chen Y
iScience 2024 Mar 15;27(3):109252

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Dietary protein restriction regulates skeletal muscle fiber metabolic characteristics associated with the FGF21-ERK1/2 pathway.

Li S, Zhong H, Wang Z, Chen J, Huang Z, Zou T, You J
iScience 2024 Mar 15;27(3):109249

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Independent prognostic value of CLDN6 in bladder cancer based on M2 macrophages related signature.

Qi D, Lu Y, Qu H, Dong Y, Jin Q, Sun M, Li Y, Quan C
iScience 2024 Mar 15;27(3):109138

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The mechanisms and therapeutic potential of clopidogrel in mitigating diabetic cardiomyopathy in db/db mice.

Li B, Zhang Y, Zheng Y, Cai H
iScience 2024 Mar 15;27(3):109134

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FTO attenuates the cytotoxicity of cisplatin in KGN granulosa cell-like tumour cells by regulating the Hippo/YAP1 signalling pathway.

Wang R, Cheng F, Yang X
Journal of ovarian research 2024 Mar 15;17(1):62

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l-Theanine delays d-galactose-induced senescence by regulating the cell cycle and inhibiting apoptosis in rat intestinal cells.

Xu W, Xiang X, Lin L, Gong ZH, Xiao WJ
Journal of the science of food and agriculture 2024 Mar 15;104(4):2073-2084

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L-Theanine alleviates heat stress through modulation of gut microbiota and immunity.

Liu S, Wang B, Lin L, Xu W, Gong ZH, Xiao WJ
Journal of the science of food and agriculture 2024 Mar 15;104(4):2059-2072

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SARS-CoV-2 remodels the Golgi apparatus to facilitate viral assembly and secretion.

Zhang J, Kennedy A, de Melo Jorge DM, Xing L, Reid W, Bui S, Joppich J, Rose M, Ercan S, Tang Q, Tai AW, Wang Y
bioRxiv : the preprint server for biology 2024 Mar 15;

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MCL1 inhibition: a promising approach to augment the efficacy of sorafenib in NSCLC through ferroptosis induction.

Huang CY, Chen LJ, Chen CS, Wang CY, Hong SY
Cell death discovery 2024 Mar 14;10(1):137

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HLA-class II restricted TCR targeting human papillomavirus type 18 E7 induces solid tumor remission in mice.

Long J, Chen X, He M, Ou S, Zhao Y, Yan Q, Ma M, Chen J, Qin X, Zhou X, Chu J, Han Y
Nature communications 2024 Mar 13;15(1):2271

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BNC1 deficiency induces mitochondrial dysfunction-triggered spermatogonia apoptosis through the CREB/SIRT1/FOXO3 pathway: the therapeutic potential of nicotinamide riboside and metformin†.

Ni F, Wang F, Li J, Liu Y, Sun X, Chen J, Li J, Zhang Y, Jin J, Ye X, Tu M, Chen J, Chen C, Zhang D
Biology of reproduction 2024 Mar 13;110(3):615-631

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Sulforaphane Regulates Macrophage M1/M2 Polarization to Attenuate Macrophage-induced Caco-2 Cell Injury in an Inflammatory Environment.

Yi T, Liu Z, Jia H, Liu Q, Peng J
Iranian journal of immunology : IJI 2024 Mar 12;21(1):37-52

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Cluster of Differentiation-44-Targeting Prussian Blue Nanoparticles Onloaded with Colchicine for Atherosclerotic Plaque Regression in a Mice Model.

Zhu Y, Fang Y, Wang Y, Han D, Liu J, Tian L, Xu M, Wang Y, Cao F
ACS biomaterials science & engineering 2024 Mar 11;10(3):1530-1543

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Synergistic effects and molecular mechanisms of DL-3-n-butylphthalide combined with dual antiplatelet therapy in acute ischemic stroke.

Du Y, Li L, Li X, Tan J, Qin Y, Lv Y, Zhai X
International immunopharmacology 2024 Mar 10;129:111592

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High-frequency repetitive transcranial magnetic stimulation improves depressive-like behaviors in CUMS-induced rats by modulating astrocyte GLT-1 to reduce glutamate toxicity.

Wang X, Zhang F, Niu L, Yan J, Liu H, Wang D, Hui J, Dai H, Song J, Zhang Z
Journal of affective disorders 2024 Mar 1;348:265-274

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Testosterone regulates thymic remodeling by altering metabolic reprogramming in male rats.

Li D, Yao H, Ren Y, Shang J, Han X, Cao X, Song T, Zeng X
General and comparative endocrinology 2024 Mar 1;348:114448

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Baiheqingjin formula reduces inflammation in mice with asthma by inhibiting the PI3K/AKT/NF-κb signaling pathway.

Yan X, Tong X, Jia Y, Zhao Y, Zhang Q, Hu M, Li X, Li B, Ming X, Xie Y, Wu X, Yu X, Qu L, Xiong L, Huang F, Nie J
Journal of ethnopharmacology 2024 Mar 1;321:117565

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From inflammation to pyroptosis: Understanding the consequences of cadmium exposure in chicken liver cells.

Li L, Xu H, Wang Y, Zhang Y, Ye R, Li W, Yang J, Wu J, Li J, Jin E, Cao M, Li X, Li S, Liu C
Ecotoxicology and environmental safety 2024 Mar 1;272:116004

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Comprehensive Atlas of Alternative Splicing Reveals NSRP1 Promoting Adipogenesis through CCDC18.

Liu L, Wang W, Liu W, Li X, Yi G, Adetula AA, Huang H, Tang Z
International journal of molecular sciences 2024 Mar 1;25(5)

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P2Y(13) receptor involved in HIV-1 gp120 induced neuropathy in superior cervical ganglia through NLRP3 inflammasome activation.

Yin S, Yang X, Li H, Li C, Li C, Chen C, Ye S, Zou L, Liang S, Liu S
Neuropharmacology 2024 Mar 1;245:109818

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Down-regulating nuclear factor of activated T cells 1 alleviates cognitive deficits in a mouse model of sepsis-associated encephalopathy, possibly by stimulating hippocampal neurogenesis.

Guo Y, Feng Y, Jiang F, Hu L, Shan T, Li H, Liao H, Bao H, Shi H, Si Y
Brain research 2024 Mar 1;1826:148731

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Decreased NSD2 impairs stromal cell proliferation in human endometrium via reprogramming H3K36me2.

Qin CM, Wei XW, Wu JY, Liu XQ, Lin Y
Reproduction (Cambridge, England) 2024 Mar 1;167(3)

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Depletion of the N(6)-Methyladenosine (m6A) reader protein IGF2BP3 induces ferroptosis in glioma by modulating the expression of GPX4.

Deng L, Di Y, Chen C, Xia J, Lei B, Li N, Zhang Q
Cell death & disease 2024 Mar 1;15(3):181

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DNAJC10 maintains survival and self-renewal of leukemia stem cells through PERK branch of the unfolded protein response.

Li M, Wu X, Chen M, Hao S, Yu Y, Li X, Zhao E, Xu M, Yu Z, Wang Z, Xu N, Jin C, Yin Y
Haematologica 2024 Mar 1;109(3):751-764

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VD(3)/VDR attenuates bisphenol A-induced impairment in mouse Leydig cells via regulation of autophagy.

Wang L, Zhuang J, Xue Z, Lu H, Zeng W, Zhang T
Journal of food science 2024 Jun;89(6):3858-3870

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Downregulation of HIGD1B induces mitochondria-mediated apoptosis in gastric cancer cells by inactivating Akt and ERK pathways.

Chen X, Sun B, Li S
Drug development research 2024 Jun;85(4):e22221

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Knocking Down PIAS3 Reduces H(2)O(2)-induced Oxidative Stress Injury in HT22 Cells.

Wang B, Qian W, Chen K, Li M, Du C
Cell biochemistry and biophysics 2024 Jun;82(2):1381-1387

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Transcriptomic analysis reveals molecular characterization and immune landscape of PANoptosis-related genes in atherosclerosis.

Zheng Z, Li K, Yang Z, Wang X, Shen C, Zhang Y, Lu H, Yin Z, Sha M, Ye J, Zhu L
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Jun;73(6):961-978

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Meningioma achieves malignancy and erastin-induced ferroptosis resistance through FOXM1-AURKA-NRF2 axis.

Ye Y, Xu L, Zhang L, Zhao P, Cai W, Fu G, Wang T, Tao Z, Shi W, Gu W, Hu J, Yuan G, Wei Y, Xu K, Bao Z, Chao H, Liu N, Zhao L, Tu Y, Ji J
Redox biology 2024 Jun;72:103137

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Jiaohong pills attenuate neuroinflammation and amyloid-β protein-induced cognitive deficits by modulating the mitogen-activated protein kinase/nuclear factor kappa-B pathway.

Zhang H, Cai W, Dong L, Yang Q, Li Q, Ran Q, Liu L, Wang Y, Li Y, Weng X, Zhu X, Chen Y
Animal models and experimental medicine 2024 Jun;7(3):222-233

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GSK-126 Attenuates Cell Apoptosis in Ischemic Brain Injury by Modulating the EZH2-H3K27me3-Bcl2l1 Axis.

Zhou T, Zhang L, He L, Lan Y, Ding L, Li L, Wang Z
Molecular neurobiology 2024 Jun;61(6):3369-3383

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HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression.

Ling H, Li Y, Peng C, Yang S, Seto E
NAR cancer 2024 Jun;6(2):zcae018

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Nanoparticulate bioceramic putty suppresses osteoclastogenesis and inflammatory bone loss in mice via inhibition of TRAF6-mediated signalling pathways: A laboratory investigation.

Wang Z, Zhang J, Sun X, Yu J, Liu B, Peng B, Wang L, Yang J, Zhu L
International endodontic journal 2024 Jun;57(6):682-699

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Dual-specificity phosphatase 26 protects against kidney injury caused by ischaemia-reperfusion through restraint of TAK1-JNK/p38-mediated apoptosis and inflammation of renal tubular epithelial cells.

Xiang H, Li Z, Li Y, Zheng J, Dou M, Xue W, Wu X
Toxicology and applied pharmacology 2024 Jun;487:116954

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Histological Features of Uterine Myometrial Dysfunction: Possible Involvement of Localized Inflammation.

Zhu SL, Zhang HT, Du YY, Jiang Y, Wang SS, Ding WC, Feng L
Current medical science 2024 Jun;44(3):633-641

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TOPK Inhibition Enhances the Sensitivity of Colorectal Cancer Cells to Radiotherapy by Reducing the DNA Damage Response.

Pang SG, Zhang X, Li ZX, He LF, Chen F, Liu ML, Huang YZ, Mo JM, Luo KL, Xiao JJ, Zhu F
Current medical science 2024 Jun;44(3):545-553

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Huoxue Jiedu Huayu recipe inhibits macrophage-secreted vascular endothelial growth factor-a on angiogenesis and alleviates renal fibrosis in the contralateral kidneys of unilateral ureteral obstruction rats.

Xiaomeng G, Panpan Q, Jingyue C, Lili F, Fan Y, Qingyou XU
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2024 Jun;44(3):458-467

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GSK3β and UCHL3 govern RIPK4 homeostasis via deubiquitination to enhance tumor metastasis in ovarian cancer.

Shan W, Peng W, Chen Y, Wang Y, Yu Q, Tian Y, Dou Y, Tu J, Huang X, Li X, Wang Z, Zhu Q, Chen J, Xia B
Oncogene 2024 Jun;43(25):1885-1899

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Quercetin, a key active ingredient of Jianpi Zishen Xiehuo Formula, suppresses M1 macrophage polarization and platelet phagocytosis by inhibiting STAT3 activation based on network pharmacology.

Wang W, Xu X, Xu Y, Zhan Y, Wu C, Xiao X, Cheng C, Gao C
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jun;397(6):4219-4233

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African swine fever virus infection regulates pyroptosis by cleaving gasdermin A via active caspase-3 and caspase-4.

Li S, Song J, Liu J, Zhou S, Zhao G, Li T, Huang L, Li J, Weng C
The Journal of biological chemistry 2024 Jun;300(6):107307

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GIP attenuates neuronal oxidative stress by regulating glucose uptake in spinal cord injury of rat.

Guo B, Qi M, Luo X, Guo L, Xu M, Zhang Y, Li Z, Li M, Wu R, Guan T, Liu M, Liu Y
CNS neuroscience & therapeutics 2024 Jun;30(6):e14806

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Caffeine upregulates SIRT3 expression to ameliorate astrocytes-mediated HIV-1 Tat neurotoxicity via suppression of EGR1 signaling pathway.

Gao L, Sun W, Zhang L, Liang C, Zhang D
Journal of neurovirology 2024 Jun;30(3):286-302

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Stevioside protects against acute kidney injury by inhibiting gasdermin D pathway.

Qiao R, Wang H, Li D, Yang Y, Shu J, Song X, Zhao X, Lu L
Smart medicine 2024 Jun;3(2):e20240010

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Insights into the effect of guanylate-binding protein 1 on the survival of Brucella intracellularly.

Li Z, Wang S, Han J, Yang G, Xi L, Zhang C, Cui Y, Yin S, Zhang Y, Zhang H
Veterinary microbiology 2024 Jun;293:110089

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p20BAP31 promotes cell apoptosis via interaction with GRP78 and activating the PERK pathway in colorectal cancer.

Jiang X, Zhu B, Li G, Cui S, Yang J, Jiang R, Wang B
International journal of biological macromolecules 2024 Jun;272(Pt 2):132870

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Expression, characterization and antivascular activity of amino acid sequence repeating collagen hexadecapeptide.

Yan W, Huang C, Yan Y, Wang P, Yuwen W, Zhu C, Fu R, Duan Z, Fan D
International journal of biological macromolecules 2024 Jun;270(Pt 1):131886

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Saccharomyces boulardii alleviates allergic asthma by restoring gut microbiota and metabolic homeostasis via up-regulation of METTL3 in an m6A-dependent manner.

Liu D, Hu L, Yang Y, Wang Y, Li Y, Su J, Wang G, Gong S
Immunology letters 2024 Jun;267:106853

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Mammalian IRE1α dynamically and functionally coalesces with stress granules.

Liu S, Zhang X, Yao X, Wang G, Huang S, Chen P, Tang M, Cai J, Wu Z, Zhang Y, Xu R, Liu K, He K, Wang Y, Jiang L, Wang QA, Rui L, Liu J, Liu Y
Nature cell biology 2024 Jun;26(6):917-931

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Landscape of transcriptome-wide m(6)A modification in diabetic liver reveals rewiring of PI3K-Akt signaling after physical exercise.

Chen C, Jiang C, Lin T, Hu Y, Wu H, Xiang Q, Yang M, Wang S, Han X, Tao J
Acta physiologica (Oxford, England) 2024 Jun;240(6):e14154

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Neutrophil extracellular traps formation may be involved in the association of propranolol with the development of portal vein thrombosis.

Xu X, Xu S, Zhang Y, Wang L, Yan C, Xu Z, Zhao Q, Qi X
Thrombosis research 2024 Jun;238:208-221

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Isobavachin attenuates osteoclastogenesis and periodontitis-induced bone loss by inhibiting cellular iron accumulation and mitochondrial biogenesis.

Li T, Du Y, Yao H, Zhao B, Wang Z, Chen R, Ji Y, Du M
Biochemical pharmacology 2024 Jun;224:116202

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Reynosin protects neuronal cells from microglial neuroinflammation by suppressing NLRP3 inflammasome activation mediated by NADPH oxidase.

Yang Y, Che Y, Fang M, Yao X, Zhou D, Wang F, Chen G, Liang D, Li N, Hou Y
Chinese journal of natural medicines 2024 Jun;22(6):486-500

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Targeting NKAα1 to treat Parkinson's disease through inhibition of mitophagy-dependent ferroptosis.

Zhang X, Li G, Chen H, Nie XW, Bian JS
Free radical biology & medicine 2024 Jun;218:190-204

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Senecavirus A induces mitophagy to promote self-replication through direct interaction of 2C protein with K27-linked ubiquitinated TUFM catalyzed by RNF185.

Chen M, Zhang X, Kong F, Gao P, Ge X, Zhou L, Han J, Guo X, Zhang Y, Yang H
Autophagy 2024 Jun;20(6):1286-1313

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Ficolin-A/2 Aggravates Severe Lung Injury through Neutrophil Extracellular Traps Mediated by Gasdermin D-Induced Pyroptosis.

Huang L, Tan X, Xuan W, Luo Q, Xie L, Xi Y, Li R, Li L, Li F, Zhao M, Jiang Y, Wu X
The American journal of pathology 2024 Jun;194(6):989-1006

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Suppression of N-Glycosylation of Zinc Finger Protein 471 Affects Proliferation, Invasion, and Docetaxel Sensitivity of Tongue Squamous Cell Carcinoma via Regulation of c-Myc.

Liu Y, Cai X, Hu S, Wang Z, Tian H, Wang H
The American journal of pathology 2024 Jun;194(6):1106-1125

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Co-exposure of microcystin and nitrite enhanced spermatogenic disorders: The role of mtROS-mediated pyroptosis and apoptosis.

Liu H, Du X, Zhang Z, Ge K, Chen X, Losiewicz MD, Guo H, Zhang H
Environment international 2024 Jun;188:108771

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Obeticholic acid attenuates the intestinal barrier disruption in a rat model of short bowel syndrome.

Hou L, Wang H, Yan M, Cai Y, Zheng R, Ma Y, Tang W, Jiang W
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167221

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Gut microbiota regulates the ALK5/NOX1 axis by altering glutamine metabolism to inhibit ferroptosis of intrahepatic cholangiocarcinoma cells.

Zhang Q, Zhou J, Zhai D, Jiang Q, Yang M, Zhou M
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167152

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OTUD1 enhances gastric cancer aggressiveness by deubiquitinating EBV-encoded protein BALF1 to stabilize the apoptosis inhibitor Bcl-2.

Lin H, Han Y, Sang Y, Wu Y, Tian M, Chen X, Lin X, Lin X
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167132

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Altered landscape of total RNA, tRNA and sncRNA modifications in the liver and spleen of mice infected by Toxoplasma gondii.

Zhang XX, Sun YZ, Wang W, Gao Y, Wei XY, Sun HC, Wang CR, Ni HB, Yang X, Elsheikha HM, Guo HP
PLoS neglected tropical diseases 2024 Jun;18(6):e0012281

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POSTN knockdown suppresses IL-1β-induced inflammation and apoptosis of nucleus pulposus cells via inhibiting the NF-κB pathway and alleviates intervertebral disc degeneration.

Wang Z, Zhu D, Yang F, Chen H, Kang J, Liu W, Lin A, Kang X
Journal of cell communication and signaling 2024 Jun;18(2):e12030

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The antidepressant effects of protein arginine methyltransferase 2 involve neuroinflammation.

Liu S, Zhang B, Guo H, Ding Z, Hou W, Hu X, Wang Y, Tan W, Zhou S
Neurochemistry international 2024 Jun;176:105728

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Novel therapeutic perspectives for wet age-related macular degeneration: RGD-modified liposomes loaded with 2-deoxy-D-glucose as a promising nanomedicine.

Chen X, Liu S, Chen M, Ni N, Zhou R, Wang Y, Xu Y, Wang Y, Gao H, Zhang D, Tang Z, Shu Q, Zhang J, Li L, Ju Y, Gu P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116776

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13-Oxyingenol-dodecanoate inhibits the growth of non-small cell lung cancer cells by targeting ULK1.

Wang XY, Wang YJ, Guo BW, Hou ZL, Zhang GX, Han Z, Liu Q, Yao GD, Song SJ
Bioorganic chemistry 2024 Jun;147:107367

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PPARG-mediated autophagy activation alleviates inflammation in rheumatoid arthritis.

Geng Q, Xu J, Cao X, Wang Z, Jiao Y, Diao W, Wang X, Wang Z, Zhang M, Zhao L, Yang L, Deng T, Fan B, Xu Y, Jia L, Xiao C
Journal of autoimmunity 2024 Jun;146:103214

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Neuroectoderm phenotypes in a human stem cell model of O-GlcNAc transferase associated with intellectual disability.

Murray M, Davidson L, Ferenbach AT, Lefeber D, van Aalten DMF
Molecular genetics and metabolism 2024 Jun;142(2):108492

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Neobractatin induces pyroptosis of esophageal cancer cells by TOM20/BAX signaling pathway.

Li Z, Bao Z, Tan J, Chen G, Ye B, Zhao J, Zhang L, Xu H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155547

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Silibinin is a suppressor of the metastasis-promoting transcription factor ID3.

Verdura S, Encinar JA, Gratchev A, Llop-Hernández À, López J, Serrano-Hervás E, Teixidor E, López-Bonet E, Martin-Castillo B, Micol V, Bosch-Barrera J, Cuyàs E, Menendez JA
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155493

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Exosomes from adipose-derived stem cells regulate macrophage polarization and accelerate diabetic wound healing via the circ-Rps5/miR-124-3p axis.

Yin D, Shen G
Immunity, inflammation and disease 2024 Jun;12(6):e1274

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E3 ubiquitin ligase CHIP interacts with transferrin receptor 1 for degradation and promotes cell proliferation through inhibiting ferroptosis in hepatocellular carcinoma.

Shao M, Qi K, Wang L, Yu X, Zhang Q, Yu L, Wang L, Yang C, Fan L
Cellular signalling 2024 Jun;118:111148

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H3K4me3-Mediated FOXJ2/SLAMF8 Axis Aggravates Thrombosis and Inflammation in β2GPI/Anti-β2GPI-Treated Monocytes.

Tan Y, Qiao J, Yang S, Liu H, Wang Q, Liu Q, Feng W, Cui L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(24):e2309140

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Peptide Transporter 1-Mediated Dipeptide Transport Promotes Hepatocellular Carcinoma Metastasis by Activating MAP4K4/G3BP2 Signaling Axis.

Song F, Zhang Z, Liu W, Xu T, Hu X, Wang Q, Zhang W, Ge L, Zhang C, Hu Q, Qin H, Zhang S, Ren X, Fan W, Zhang Y, Huang P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(24):e2306671

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Single-Nucleus Multiomic Analyses Identifies Gene Regulatory Dynamics of Phenotypic Modulation in Human Aneurysmal Aortic Root.

Liu X, Zeng Q, Yang H, Li W, Chen Q, Yin K, Pan Z, Wang K, Luo M, Shu C, Zhou Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(22):e2400444

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Experimental verification about treatment of Bu-Shen-Yi-Jing-Fang in Alzheimer's disease by the analysis of the feasible signaling pathway of network pharmacology.

Hu Y, Hao R, Li D, Lu Y, Yu G
BMC complementary medicine and therapies 2024 Jun 8;24(1):222

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OLFM4 promotes the progression of intestinal metaplasia through activation of the MYH9/GSK3β/β-catenin pathway.

Wei H, Li W, Zeng L, Ding N, Li K, Yu H, Jiang F, Yin H, Xia Y, Deng C, Cai N, Chen X, Gu L, Chen H, Zhang F, He Y, Li J, Zhang C
Molecular cancer 2024 Jun 7;23(1):124

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m(6)A Methylation Mediates the Function of the circRNA-08436/miR-195/ELOVL6 Axis in Regards to Lipid Metabolism in Dairy Goat Mammary Glands.

Wang Y, Wu Y, Yang S, Gao R, Lv X, Yang Z, Jiao P, Zhang N, Loor JJ, Chen Z
Animals : an open access journal from MDPI 2024 Jun 7;14(12)

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Deficiency of SDHC promotes metastasis by reprogramming fatty acid metabolism in colorectal cancer.

Ding Z, Wei Y, Dai J, Pan C, Yang L, Li Q, Zhang Y, Yan Q, Wu C, Li A, Lan Z, Liu S, Wang X
Journal of translational medicine 2024 Jun 6;22(1):544

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Discovery of 4-benzylpiperazinequinoline BChE inhibitor that suppresses neuroinflammation for the treatment of Alzheimer's disease.

Chen Y, Zhang W, Li Q, Xie H, Xing S, Lu X, Lyu W, Xiong B, Wang Y, Qu W, Liu W, Chi H, Zhang X, Feng F, Sun H
European journal of medicinal chemistry 2024 Jun 5;272:116463

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The manganese transporter SLC39A8 links alkaline ceramidase 1 to inflammatory bowel disease.

Choi EK, Rajendiran TM, Soni T, Park JH, Aring L, Muraleedharan CK, Garcia-Hernandez V, Kamada N, Samuelson LC, Nusrat A, Iwase S, Seo YA
Nature communications 2024 Jun 5;15(1):4775

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Chemical screen in zebrafish lateral line identified compounds that ameliorate neomycin-induced ototoxicity by inhibiting ferroptosis pathway.

Fan Y, Zhang Y, Qin D, Shu X
Cell & bioscience 2024 Jun 5;14(1):71

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Microglial lipid droplet accumulation in tauopathy brain is regulated by neuronal AMPK.

Li Y, Munoz-Mayorga D, Nie Y, Kang N, Tao Y, Lagerwall J, Pernaci C, Curtin G, Coufal NG, Mertens J, Shi L, Chen X
Cell metabolism 2024 Jun 4;36(6):1351-1370.e8

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A comparative study of the hypolipidemic effects and mechanisms of action of Laminaria japonica- and Ascophyllum nodosum-derived fucoidans in apolipoprotein E-deficient mice.

Liu T, Wang X, Wang YM, Sui FR, Zhang XY, Liu HD, Ma DY, Liu XX, Guo SD
Food & function 2024 Jun 4;15(11):5955-5971

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Calmodulin Contributes to Lipolysis and Inflammatory Responses in Clinical Ketosis Cows through the TLR4/IKK/NF-κB Pathway.

Chang J, Wang Z, Hao Y, Song Y, Xia C
Animals : an open access journal from MDPI 2024 Jun 4;14(11)

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Proteomics analysis of PK-15 cells infected with porcine parvovirus and the effect of PCBP1 on PPV replication.

Wang L, Song Y, Xu M, Zhang C, Zhang L, Xia L, Wei Z
Microbiology spectrum 2024 Jun 4;12(6):e0391423

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RNA sequencing screening and gene function analysis uncover G protein-coupled receptor 183 as a key mediator for methionine to stimulate milk synthesis in mouse mammary epithelial cells.

Zhou Y, Fan S, Xu M, Zhang M, Gao X
The British journal of nutrition 2024 Jun 4;:1-13

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P53 upregulation by USP7-engaging molecular glues.

Li Z, Wang Z, Zhong C, Zhang H, Liu R, An P, Ma Z, Lu J, Pan C, Zhang Z, Cao Z, Hu J, Xing D, Fei Y, Ding Y, Lu B
Science bulletin 2024 Jun 30;69(12):1936-1953

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CSF3 aggravates acute exacerbation of pulmonary fibrosis by disrupting alveolar epithelial barrier integrity.

Guo B, Liu W, Ji X, Xi B, Meng X, Xie W, Sun Y, Zhang M, Liu P, Zhang W, Yan X, Chen B
International immunopharmacology 2024 Jun 30;135:112322

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Isorhamnetin alleviates ferroptosis-mediated colitis by activating the NRF2/HO-1 pathway and chelating iron.

Ru Y, Luo Y, Liu D, Huang Q, Zhou X, Linghu M, Luo X, Lv Z, Wu Y, Zhang H, Huang Y
International immunopharmacology 2024 Jun 30;135:112318

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Fraxinellone alleviates colitis-related intestinal fibrosis by blocking the circuit between PD-1(+) Th17 cells and fibroblasts.

Xu Y, Zheng C, Jiang P, Ji S, Ullah S, Zhao Y, Su D, Xu G, Zhang M, Zou X
International immunopharmacology 2024 Jun 30;135:112298

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IRG1/itaconate alleviates acute liver injury in septic mice by suppressing NLRP3 expression and its mediated macrophage pyroptosis via regulation of the Nrf2 pathway.

Zhou P, Yang L, Li R, Yin Y, Xie G, Liu X, Shi L, Tao K, Zhang P
International immunopharmacology 2024 Jun 30;135:112277

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The STAT3 inhibitor B9 alleviates lipopolysaccharide-induced acute lung injury through its anti-inflammatory effects.

Cao L, Song H, Zhou S, Lan K, Lv K, Huang M
International immunopharmacology 2024 Jun 30;135:112221

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Caffeic acid and diabetic neuropathy: Investigating protective effects and insulin-like growth factor 1 (IGF-1)-related antioxidative and anti-inflammatory mechanisms in mice.

Hou L, Ma J, Feng X, Chen J, Dong BH, Xiao L, Zhang X, Guo B
Heliyon 2024 Jun 30;10(12):e32623

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The Role of Ubiquitination and the E3 Ligase Nedd4 in Regulating Corneal Epithelial Wound Healing.

Ling X, Xu W, Tang J, Cao Q, Luo G, Chen X, Yang S, Reinach PS, Yan D
Investigative ophthalmology & visual science 2024 Jun 3;65(6):29

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m6Am methyltransferase PCIF1 negatively regulates ciliation by inhibiting BICD2 expression.

Xie S, Kuang W, Guo M, Yang F, Jin H, Chen X, Yi L, Huo C, Xu Z, Lin A, Liu W, Mao J, Shu Q, Zhou T
The Journal of cell biology 2024 Jun 3;223(6)

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Intermittent hypoxia training enhances Aβ endocytosis by plaque associated microglia via VPS35-dependent TREM2 recycling in murine Alzheimer's disease.

Wang X, Xie Y, Fan X, Wu X, Wang D, Zhu L
Alzheimer's research & therapy 2024 Jun 3;16(1):121

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TSWIFT, a novel method for iterative staining of embedded and mounted human brain sections.

Porter CM, Tabler S, Choi S, Truttmann MC
Scientific reports 2024 Jun 3;14(1):12688

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Defective interferon signaling in the circulating monocytes of type 2 diabetic mice.

Omodaka S, Kato Y, Sato Y, Falcone-Juengert J, Zhang H, Kanoke A, Eckalbar WL, Endo H, Hsieh CL, Aran D, Liu J
bioRxiv : the preprint server for biology 2024 Jun 3;

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The effect of miR‑155‑5p on long‑term memory of sleep‑deprived mice through the BDNF/NF‑κB pathway.

Hou D, Zhong J, Hu Y, Yang G
Acta neurobiologiae experimentalis 2024 Jun 28;84(2):203-217

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PTPN23[Thr] variant reduces susceptibility and tumorigenesis in esophageal squamous cell carcinoma through dephosphorylation of EGFR.

Niu S, Ma J, Li Y, Yue X, Shi K, Pan M, Song L, Tan Y, Gu L, Liu S, Chang J
Cancer letters 2024 Jun 28;592:216936

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Chishao - Fuzi herbal pair restore the macrophage M1/M2 balance in acute-on-chronic liver failure.

Tan N, Jian G, Peng J, Tian X, Chen B
Journal of ethnopharmacology 2024 Jun 28;328:118010

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MicroRNA-384 radiosensitizes human non-small cell lung cancer by impairing DNA damage response and repair signaling, which is inhibited by NF-κB.

Sun Y, Wang J, Qiu M, Zhao J, Zou F, Meng M, Jiang X, Yuan Z, Mi Z, Wu Z
Cancer biology & medicine 2024 Jun 27;21(11):1050-66

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PGC1-Alpha/Sirt3 Signaling Pathway Mediates the Anti-Pulmonary Fibrosis Effect of Hirudin by Inhibiting Fibroblast Senescence.

He B, Zeng Q, Tian Y, Luo Y, Liao M, Huang W, Wu B, Luo Z, Huang X, Liu W, Tang S
Biomedicines 2024 Jun 27;12(7)

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Identification and Validation of JAM-A as a Novel Prognostic and Immune Factor in Human Tumors.

Ren T, Zheng Y, Liu F, Liu C, Zhang B, Ren H, Gao X, Wei Y, Sun Q, Huang H
Biomedicines 2024 Jun 26;12(7)

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Mammalian orthoreovirus capsid protein σ3 antagonizes RLR-mediated antiviral responses by degrading MAVS.

Li D, Mo R, Li X, Cheng R, Xie J, Li H, Yang Y, Li S, Li H, Yan Z, Wei S, Idris A, Li X, Feng R
mSphere 2024 Jun 25;9(6):e0023624

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A Novel Role for Protein Tyrosine Phosphatase 1B in Alleviating Chondrocyte Senescence.

Li HM, Che X, Tong Z, Wei W, Teng C
ACS omega 2024 Jun 25;9(25):27017-27029

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CRACD loss induces neuroendocrine cell plasticity of lung adenocarcinoma.

Kim B, Zhang S, Huang Y, Ko KP, Jung YS, Jang J, Zou G, Zhang J, Jun S, Kim KB, Park KS, Park JI
Cell reports 2024 Jun 25;43(6):114286

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Stress granule-localized USP8 potentiates cGAS-mediated type I interferonopathies through deubiquitination of DDX3X.

Zhang X, Han L, Hou J, Yang H, Xu H, Li G, Shu Q, Zhu D, Zheng Y, Gao C
Cell reports 2024 Jun 25;43(6):114248

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VHL suppresses UBE3B-mediated breast tumor growth and metastasis.

Wang S, Li H, Liu X, Yin T, Li T, Zheng M, Liu M, Meng X, Zhou J, Wang Y, Chen Y
Cell death & disease 2024 Jun 24;15(6):446

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Combined Proteomic and Metabolomic Analysis Reveals Comprehensive Regulation of Somatostatin DNA Vaccine in Goats.

Qin G, Zhang L, Guo J, Fang S, E G, Zeng Y, Huang Y, Han Y
International journal of molecular sciences 2024 Jun 23;25(13)

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Protocol for identifying OXCT1-mediated LACTB succinylation sites in vitro.

Ma W, Sun Y, Zhang H
STAR protocols 2024 Jun 21;5(2):103088

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ZEB2 alleviates Hirschsprung's-associated enterocolitis by promoting the proliferation and differentiation of enteric neural precursor cells via the Notch-1/Jagged-2 pathway.

Feng Y, Zhou C, Zhao F, Ma T, Xiao Y, Peng K, Xia R
Gene 2024 Jun 20;912:148365

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SRSF3 Knockdown Inhibits Lipopolysaccharide-Induced Inflammatory Response in Macrophages.

Fu Y, Wang Y, Zhang L, He T, Shi W, Guo X, Wang Y
Current issues in molecular biology 2024 Jun 20;46(6):6237-6247

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Chemotherapy-induced high expression of IL23A enhances efficacy of anti-PD-1 therapy in TNBC by co-activating the PI3K-AKT signaling pathway of CTLs.

Pan F, Liu J, Chen Y, Zhu B, Chen W, Yang Y, Zhu C, Zhao H, Liu X, Xu Y, Xu X, Huo L, Xie L, Wang R, Gu J, Huang G
Scientific reports 2024 Jun 20;14(1):14248

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The Combination of Lactoferrin and Creatine Ameliorates Muscle Decay in a Sarcopenia Murine Model.

Wu W, Guo X, Qu T, Huang Y, Tao J, He J, Wang X, Luo J, An P, Zhu Y, Sun Y, Luo Y
Nutrients 2024 Jun 19;16(12)

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Macrophages exploit the mannose receptor and JAK-STAT1-MHC-II pathway to drive antigen presentation and the antimycobacterial immune response after BCG vaccination.

Zhang Y, Xu D, Nie Q, Wang J, Fang D, Xie Y, Xiong H, Pan Q, Zhang XL
Acta biochimica et biophysica Sinica 2024 Jun 18;56(8):1130-1144

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Development of a PCSK9-targeted nanoparticle vaccine to effectively decrease the hypercholesterolemia.

Fang Q, Lu X, Zhu Y, Lv X, Yu F, Ma X, Liu B, Zhang H
Cell reports. Medicine 2024 Jun 18;5(6):101614

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Graphene Far-Infrared Irradiation Can Effectively Relieve the Blood Pressure Level of Rat Untr-HT in Primary Hypertension.

Lu G, Guo H, Zhang Y, Zhang M, Zhang T, Hu G, Zhang Q
International journal of molecular sciences 2024 Jun 18;25(12)

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Functional genetic variants of GEN1 predict overall survival of Chinese epithelial ovarian cancer patients.

Li H, Wu J, Xu Q, Pang Y, Gu Y, Wang M, Cheng X
Journal of translational medicine 2024 Jun 18;22(1):577

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Transcriptomic profiling highlights cell proliferation in the progression of experimental pulmonary hypertension in rats.

Luo A, Hao R, Zhou X, Jia Y, Bao C, Yang L, Zhou L, Gu C, Desai AA, Tang H, Chu AA
Scientific reports 2024 Jun 18;14(1):14056

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PEG300 Protects Mitochondrial Function By Upregulating PGC-1α to Delay Central Nervous System Oxygen Toxicity in Mice.

Li X, Shen Y, Li D, Zhang K, Liu J, Yao L, Yang J, Qian J
Neurotoxicity research 2024 Jun 17;42(4):30

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The Selective SIRT3 Inhibitor 3-TYP Represses Primary Myeloma Growth by Reducing c-Myc Stability.

Zeng Y, Zhang Y, Cui Z, Mao J, Xu J, Yao R
Chemical research in toxicology 2024 Jun 17;37(6):1062-1069

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Iron deficiency affects oxygen transport and activates HIF1 signaling pathway to regulate phenotypic transformation of VSMC in aortic dissection.

Chen Y, Li X, Wang Z, Yuan S, Shen X, Xie X, Xing K, Zhu Q
Molecular medicine (Cambridge, Mass.) 2024 Jun 17;30(1):90

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The deubiquitinating protein OTUD6B promotes lung adenocarcinoma progression by stabilizing RIPK1.

Yang M, Wei Y, He X, Xia C
Biology direct 2024 Jun 16;19(1):46

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EEF1B2 regulates bone marrow-derived mesenchymal stem cells bone-fat balance via Wnt/β-catenin signaling.

Feng S, Feng Z, Wei Y, Zheng X, Deng Z, Liao Z, Jin Y, Chen R, Zhao L
Cellular and molecular life sciences : CMLS 2024 Jun 15;81(1):260

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Neurotoxicity of manganese via ferroptosis induced by redox imbalance and iron overload.

Wang C, Zhao H, Liu Y, Qu M, Lv S, He G, Liang H, Chen K, Yang L, He Y, Ou C
Ecotoxicology and environmental safety 2024 Jun 15;278:116404

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Empirical analysis of lead neurotoxicity mode of action and its application in health risk assessment.

Huang H, Lv Y, Chen Q, Huang X, Qin J, Liu Y, Liao Q, Xing X, Chen L, Liu Q, Li S, Long Z, Wang Q, Chen W, Wei Q, Hou M, Hu Q, Xiao Y
Environmental research 2024 Jun 15;251(Pt 2):118708

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Microglial SIX2 suppresses lipopolysaccharide (LPS)-induced neuroinflammation by up-regulating FXYD2 expression.

Cao XY, Liu Y, Kan JS, Huang XX, Kambey PA, Zhang CT, Gao J
Brain research bulletin 2024 Jun 15;212:110970

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Involvement of P2X7R-mediated microglia polarization and neuroinflammation in the response to electroacupuncture on post-stroke memory impairment.

Lin B, Wang M, Chen X, Chai L, Ni J, Huang J
Brain research bulletin 2024 Jun 15;212:110967

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CK1δ/ε kinases regulate TDP-43 phosphorylation and are therapeutic targets for ALS-related TDP-43 hyperphosphorylation.

Ko VI, Ong K, Cleveland DW, Yu H, Ravits JM
Neurobiology of disease 2024 Jun 15;196:106516

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X-Paste improves wound healing in diabetes via NF-E2-related factor/HO-1 signaling pathway.

Du MW, Zhu XL, Zhang DX, Chen XZ, Yang LH, Xiao JZ, Fang WJ, Xue XC, Pan WH, Liao WQ, Yang T
World journal of diabetes 2024 Jun 15;15(6):1299-1316

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Menaquinone-4 alleviates hypoxic-ischemic brain damage in neonatal rats by reducing mitochondrial dysfunction via Sirt1-PGC-1α-TFAM signaling pathway.

Feng X, Zheng Y, Mao N, Shen M, Chu L, Fang Y, Pang M, Wang Z, Lin Z
International immunopharmacology 2024 Jun 15;134:112257

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Diosmetin ameliorates psoriasis-associated inflammation and keratinocyte hyperproliferation by modulation of PGC-1α / YAP signaling pathway.

Yang D, Peng M, Fu F, Zhao W, Zhang B
International immunopharmacology 2024 Jun 15;134:112248

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Inhibiting the SARM1-NAD(+) axis reduces oxidative stress-induced damage to retinal and nerve cells.

Zhang Y, Yao Y, Yang J, Zhou B, Zhu Y
International immunopharmacology 2024 Jun 15;134:112193

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New strategy to treat spinal cord injury: Nafamostat mesilate suppressed NLRP3-mediated pyroptosis during acute phase.

Lou Y, Li Z, Zheng H, Yuan Z, Li W, Zhang J, Shen W, Gao Y, Ran N, Kong X, Feng S
International immunopharmacology 2024 Jun 15;134:112190

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Processing of angiocrine alarmin IL-1α in endothelial cells promotes lung and liver fibrosis.

Zhang C, Ma J, Zhang X, Zhou D, Cao Z, Qiao L, Chen G, Yang L, Ding BS
International immunopharmacology 2024 Jun 15;134:112176

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SIAH1 facilitates the migration and invasion of gastric cancer cells through promoting the ubiquitination and degradation of RECK.

Zhou X, Gao F, Xu G, Puyang Y, Rui H, Li J
Heliyon 2024 Jun 15;10(11):e32676

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Exserolide J ameliorates lipid accumulation in vitro by regulating liver X receptor alpha and peroxisome proliferator-activated receptor alpha proteins.

Zhang Y, Wang X, Liu T, Zhang ZY, Song WG, Guo SD
Heliyon 2024 Jun 15;10(11):e31861

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YTHDC1 inhibits autophagy-dependent NF-κB signaling by stabilizing Beclin1 mRNA in macrophages.

Zhou L, Zhang L, Lv Y, Qian J, Huang L, Qu C
Journal of inflammation (London, England) 2024 Jun 14;21(1):22

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IRTKS contributes to the malignant progression of cervical cancer cells.

Zhang Y, Yi F, Zhang X, Song J, Cai J, Lai J, Song F
Medical oncology (Northwood, London, England) 2024 Jun 13;41(7):174

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Silencing immune-infiltrating biomarker CCDC80 inhibits malignant characterization and tumor formation in gastric cancer.

Yu M, Peng J, Lu Y, Li S, Ding K
BMC cancer 2024 Jun 13;24(1):724

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Procyanidin B1 and Coumaric Acid from Highland Barley Alleviated High-Fat-Diet-Induced Hyperlipidemia by Regulating PPARα-Mediated Hepatic Lipid Metabolism and Gut Microbiota in Diabetic C57BL/6J Mice.

Liu Z, Liu J, Tang R, Zhang Z, Tian S
Foods (Basel, Switzerland) 2024 Jun 12;13(12)

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Quantitative Proteomics Reveal the Role of Matrine in Regulating Lipid Metabolism.

Feng H, Liu G, Li L, Ren X, Jiang Y, Hou W, Liu R, Liu K, Liu H, Huang H
ACS omega 2024 Jun 11;9(23):24308-24320

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MYG1 drives glycolysis and colorectal cancer development through nuclear-mitochondrial collaboration.

Chen J, Duan S, Wang Y, Ling Y, Hou X, Zhang S, Liu X, Long X, Lan J, Zhou M, Xu H, Zheng H, Zhou J
Nature communications 2024 Jun 11;15(1):4969

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Effect of scutellarin on BV-2 microglial-mediated apoptosis in PC12 cells via JAK2/STAT3 signalling pathway.

Duan ZD, Zheng LY, Jia QY, Chen HL, Xu DY, Yang YJ, Qi Z, Yang L, Wu CY
Scientific reports 2024 Jun 11;14(1):13430

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FBXO43 promotes cell cycle progression in cancer cells through stabilizing SKP2.

Zheng L, Shen J, Chen Y, Lin J, Li P, Zhao X, Ren H, Sun Y, Wang Z
Cancer letters 2024 Jun 1;591:216848

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GADD45B in the ventral hippocampal CA1 modulates aversive memory acquisition and spatial cognition.

Huang M, Tao X, Bao J, Wang J, Gong X, Luo L, Pan S, Yang R, Gui Y, Zhou H, Xia Y, Yang Y, Sun B, Liu W, Shu X
Life sciences 2024 Jun 1;346:122618

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Structural elucidation and anti-psoriasis activity of a novel polysaccharide from Saussurea Costus.

Gong X, Zhang Z, Shi X, Zhu Y, Ali F, Dong Y, Zhang F, Zhang B
Carbohydrate polymers 2024 Jun 1;333:121963

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Polystyrene microplastics induce pulmonary fibrosis by promoting alveolar epithelial cell ferroptosis through cGAS/STING signaling.

Zhang J, Du J, Liu D, Zhuo J, Chu L, Li Y, Gao L, Xu M, Chen W, Huang W, Xie L, Chen J, Meng X, Zou F, Cai S, Dong H
Ecotoxicology and environmental safety 2024 Jun 1;277:116357

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The mitochondria-targeted antioxidant MitoQ ameliorates inorganic arsenic-induced DCs/Th1/Th2/Th17/Treg differentiation partially by activating PINK1-mediated mitophagy in murine liver.

Li H, Guo Y, Su W, Zhang H, Wei X, Ma X, Gong S, Qu G, Zhang L, Xu H, Shen F, Jiang S, Xu D, Li J
Ecotoxicology and environmental safety 2024 Jun 1;277:116350

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HO-1 upregulation promotes mitophagy-dependent ferroptosis in PM2.5-exposed hippocampal neurons.

Li X, Ran Q, He X, Peng D, Xiong A, Jiang M, Zhang L, Wang J, Bai L, Liu S, Li S, Sun B, Li G
Ecotoxicology and environmental safety 2024 Jun 1;277:116314

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Amelioration of NAFLD by sleeve gastrectomy-triggered hepatocyte regeneration in mice - experimental research.

Yu T, Ma X, Cheng Y, Wang Z, Zhang G, Ding H, Yin J, Wang Y, Hu S
International journal of surgery (London, England) 2024 Jun 1;110(6):3307-3325

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DACH1 Attenuates Airway Inflammation in Chronic Obstructive Pulmonary Disease by Activating NRF2 Signaling.

Huang Q, Gu Y, Wu J, Zhan Y, Deng Z, Chen S, Peng M, Yang R, Chen J, Xie J
American journal of respiratory cell and molecular biology 2024 Jul;71(1):121-132

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Exosomal LncRNA TM7SF3-AU1 Aggravates White Matter Injury via MiR-702-3p/SARM1 Signaling After Subarachnoid Hemorrhage in Rats.

Zhang Z, Yan J, Chen H, Zhao G, Liu L, He J, Xia X, Zhou C, Sun X
Molecular neurobiology 2024 Jul;61(7):4783-4803

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Rack1-mediated ferroptosis affects hindgut development in rats with anorectal malformations: Spatial transcriptome insights.

Wang CY, Li MY, Li SY, Wei XG, Dong NX, Liu ST, Yuan ZW, Li B, Pierro A, Tang XB, Bai YZ
Cell proliferation 2024 Jul;57(7):e13618

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YAP1 inhibits the senescence of alveolar epithelial cells by targeting Prdx3 to alleviate pulmonary fibrosis.

Su W, Guo Y, Wang Q, Ma L, Zhang Q, Zhang Y, Geng Y, Jin T, Guo J, Yang R, Niu Z, Ren L, Wang Y, Ning Z, Li W, He W, Sun J, Li T, Li Z, Shan H, Liang H
Experimental & molecular medicine 2024 Jul;56(7):1643-1654

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Distinguishing high-metastasis-potential circulating tumor cells through fluidic shear stress in a bloodstream-like microfluidic circulatory system.

Li W, Guo Z, Zhou Z, Zhou Z, He H, Sun J, Zhou X, Chin YR, Zhang L, Yang M
Oncogene 2024 Jul;43(30):2295-2306

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MCM8 interacts with DDX5 to promote R-loop resolution.

Wen C, Cao L, Wang S, Xu W, Yu Y, Zhao S, Yang F, Chen ZJ, Zhao S, Yang Y, Qin Y
The EMBO journal 2024 Jul;43(14):3044-3071

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Role of formyl peptide receptor 2 in steatosis of L02 cells exposed to Mono-(2-ethylhexyl) phthalate.

Feng X, Zhang R, Miao X, Li X, Cui J, Xu H, Fang X, Zhou C, Ye L, Zhou L
Environmental toxicology 2024 Jul;39(7):3967-3979

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MicroRNA-505-3p mediates cell motility of epithelial ovarian cancer via suppressing PEAK1 expression.

Wu Y, Xue L, Xiong W, Li H, Wu J, Xie W, Long Y, Liu Y, Luo C
Journal of biochemical and molecular toxicology 2024 Jul;38(7):e23767

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The cooperative regulatory effect of the miRNA-130 family on milk fat metabolism in dairy cows.

Li X, Wu Y, Yang X, Gao R, Lu Q, Lv X, Chen Z
Animal bioscience 2024 Jul;37(7):1289-1302

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ATXN3 functions as a tumor suppressor through potentiating galectin-9-mediated apoptosis in human colon adenocarcinoma.

Cheng Y, Wang S, Gao Q, Fang D
The Journal of biological chemistry 2024 Jul;300(7):107415

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Effectiveness and mechanisms of combined use of antioxidant nutrients in protecting against oxidative stress-induced neuronal loss and related neurological deficits.

Wang L, Wei Y, Sun Z, Tai W, Li H, Yin Y, Jiang LH, Wang JZ
CNS neuroscience & therapeutics 2024 Jul;30(7):e14886

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An arabinogalactan isolated from Cynanchum atratum promotes lymphangiogenesis and lymphatic vessel remodeling to alleviate secondary lymphedema.

Li N, Ruan M, Chen W, Han Y, Yang K, Xu H, Shi S, Wang S, Wang H, Wang Y, Liang Q
International journal of biological macromolecules 2024 Jul;273(Pt 2):133061

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Fibroblast growth factor 21 alleviates idiopathic pulmonary fibrosis by inhibiting PI3K-AKT-mTOR signaling and stimulating autophagy.

Qi J, Wu Y, Guo Z, Zhu S, Xiong J, Hu F, Liang X, Ye X
International journal of biological macromolecules 2024 Jul;273(Pt 1):132896

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A dual role of ERGIC-localized Rabs in TMED10-mediated unconventional protein secretion.

Sun Y, Tao X, Han Y, Lin X, Tian R, Wang H, Chang P, Sun Q, Ge L, Zhang M
Nature cell biology 2024 Jul;26(7):1077-1092

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Adaptor protein 14-3-3zeta promotes corneal wound healing via regulating cell homeostasis, a potential novel therapy for corneal injury.

Jiang Y, Chen M, Xu N, Li Z, Li X, Yu H, Sun J, Wang A, Huang Y, Wang L
Experimental eye research 2024 Jul;244:109948

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MICAL-L2, as an estrogen-responsive gene, is involved in ER-positive breast cancer cell progression and tamoxifen sensitivity via the AKT/mTOR pathway.

Wen P, Li J, Wen Z, Guo X, Ma G, Hu S, Xu J, Zhao H, Li R, Liu Y, Wang Y, Gao J
Biochemical pharmacology 2024 Jul;225:116256

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Selective microRNA expression of exosomes from retinal pigment epithelial cells by oxidative stress.

Zhang Z, Gu Q, Chen L, Yuan D, Gu X, Qian H, Xie P, Liu Q, Hu Z
Vision research 2024 Jul;220:108388

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Picroside II promotes HSC apoptosis and inhibits the cholestatic liver fibrosis in Mdr2(-/-) mice by polarizing M1 macrophages and balancing immune responses.

Jia K, Ma Z, Zhang Y, Xie K, Li J, Wu J, Qu J, Li F, Li X
Chinese journal of natural medicines 2024 Jul;22(7):582-598

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Rocaglamide regulates iron homeostasis by suppressing hepcidin expression.

Zhu X, Zuo Q, Xie X, Chen Z, Wang L, Chang L, Liu Y, Luo J, Fang C, Che L, Zhou X, Yao C, Gong C, Hu D, Zhao W, Zhou Y, Zhu S
Free radical biology & medicine 2024 Jul;219:153-162

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RACK1 enhances STAT3 stability and promotes T follicular helper cell development and function during blood-stage Plasmodium infection in mice.

Cheng Q, Yang X, Zou T, Sun L, Zhang X, Deng L, Wu M, Gai W, Jiang H, Guo T, Lu Y, Dong J, Niu C, Pan W, Zhang J
PLoS pathogens 2024 Jul;20(7):e1012352

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A genome-wide CRISPR/Cas9 knockout screen identifies TMEM239 as an important host factor in facilitating African swine fever virus entry into early endosomes.

Shen D, Zhang G, Weng X, Liu R, Liu Z, Sheng X, Zhang Y, Liu Y, Mu Y, Zhu Y, Sun E, Zhang J, Li F, Xia C, Ge J, Liu Z, Bu Z, Zhao D
PLoS pathogens 2024 Jul;20(7):e1012256

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Cryptochrome 2 Suppresses Epithelial-Mesenchymal Transition by Promoting Trophoblastic Ferroptosis in Unexplained Recurrent Spontaneous Abortion.

Li F, Guo L, Zhou M, Han L, Wu S, Wu L, Yang J
The American journal of pathology 2024 Jul;194(7):1197-1217

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Direct vagus nerve stimulation: A new tool to control allergic airway inflammation through α7 nicotinic acetylcholine receptor.

Sévoz-Couche C, Liao W, Foo HYC, Bonne I, Lu TB, Tan Qi Hui C, Azhar SH, Peh WYX, Yen SC, Wong WSF
British journal of pharmacology 2024 Jul;181(13):1916-1934

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Insect cells of Spodoptera frugiperda support WSSV gene replication but not progeny virion assembly.

Jing SS, Liu LK, Liu HP
Developmental and comparative immunology 2024 Jul;156:105160

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GBP2 inhibits pathological angiogenesis in the retina via the AKT/mTOR/VEGFA axis.

Xu X, Ding X, Wang Z, Ye S, Xu J, Liang Z, Luo R, Xu J, Li X, Ren Z
Microvascular research 2024 Jul;154:104689

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Electroacupuncture improves articular microcirculation and attenuates cartilage hypoxia in a male rabbit model of knee osteoarthritis.

Weiwei M, Mei D, Juan L, Longfei X, Xilin C, Tingyao H, Wenting Z, Changqing G
Journal of traditional and complementary medicine 2024 Jul;14(4):414-423

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METTL1/FOXM1 promotes lung adenocarcinoma progression and gefitinib resistance by inhibiting PTPN13 expression.

Peng W, Fu J, Zhou L, Duan H
Cancer medicine 2024 Jul;13(13):e7420

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Bushen Huoxue recipe ameliorates ovarian function via promoting BMSCs proliferation and homing to ovaries in POI mice.

Huang Y, Hu R, Liu Z, Geng Y, Li F, Song Y, Ma W, Dong H, Xu L, Zhang M, Song K
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155630

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Shenfu injection targets the PI3K-AKT pathway to regulate autophagy and apoptosis in acute respiratory distress syndrome caused by sepsis.

Chen J, Ding W, Zhang Z, Li Q, Wang M, Feng J, Zhang W, Cao L, Ji X, Nie S, Sun Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155627

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Salvia miltiorrhiza Bge. processed with porcine cardiac blood inhibited GLRX5-mediated ferroptosis alleviating cerebral ischemia-reperfusion injury.

Zhou S, Wang Z, Wang T, Peng C, Zhang J, Liu C, Xu J, Zhang Y, Zhang L, Luo L, Yan X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155622

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Bergenin alleviates proliferative arterial diseases by modulating glucose metabolism in vascular smooth muscle cells.

Song Y, Deng M, Qiu Y, Cui Y, Zhang B, Xin J, Feng L, Mu X, Cui J, Li H, Sun Y, Yi W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155592

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Exploring the anti-skin inflammation substances and mechanism of Paeonia lactiflora Pall. Flower via network pharmacology-HPLC integration.

Chen Y, Li H, Zhang XL, Wang W, Rashed MMA, Duan H, Li LL, Zhai KF
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155565

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Genome sequence and cell biological toolbox of the highly regenerative, coenocytic green feather alga Bryopsis.

Ochiai KK, Hanawa D, Ogawa HA, Tanaka H, Uesaka K, Edzuka T, Shirae-Kurabayashi M, Toyoda A, Itoh T, Goshima G
The Plant journal : for cell and molecular biology 2024 Jul;119(2):1091-1111

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Active secretion of IL-33 from astrocytes is dependent on TMED10 and promotes central nervous system homeostasis.

Jiao M, Wang C, Tang X, Dai C, Zhang N, Fan A, Qian Z, Liu S, Zhang F, Li B, Xu Y, Tan Z, Gong F, Lu Y, Zheng F
Brain, behavior, and immunity 2024 Jul;119:539-553

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CXXC5 drove inflammation and ovarian cancer proliferation via transcriptional activation of ZNF143 and EGR1.

Geng T, Sun Q, He J, Chen Y, Cheng W, Shen J, Liu B, Zhang M, Wang S, Asan K, Song M, Gao Q, Song Y, Liu R, Liu X, Ding Y, Jing A, Ye X, Ren H, Zeng K, Zhou Y, Zhang B, Ma S, Liu W, Liu S, Ji J
Cellular signalling 2024 Jul;119:111180

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Transient stimulation of TRPMLs enhance the functionality of hDPCs and facilitate hair growth in mice.

Sun J, Zhang H, Xie B, Shen Y, Zhu Y, Xu W, Zhang B, Song X
Cellular signalling 2024 Jul;119:111167

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Adiponectin inhibits ROS/NLRP3 inflammatory pathway through FOXO3A to ameliorate oral submucosal fibrosis.

Zeng Y, Luo M, Yao Z, Xiao X
Odontology 2024 Jul;112(3):811-825

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Luteolin alleviates cadmium-induced metabolism disorder through antioxidant and anti-inflammatory mechanisms in chicken kidney.

Wang X, Zhang K, Ali W, Li J, Huang Q, Liu D, Liu G, Ran D, Liu Z
Poultry science 2024 Jul;103(7):103817

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METTL3-mediated NDUFB5 m6A modification promotes cell migration and mitochondrial respiration to promote the wound healing of diabetic foot ulcer.

Wang T, Li X, Tao Y, Wang X, Li L, Liu J
Journal of translational medicine 2024 Jul 9;22(1):643

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Neurosteroid [3α,5α]-3-Hydroxy-pregnan-20-one Enhances the CX3CL1-CX3CR1 Pathway in the Brain of Alcohol-Preferring Rats with Sex-Specificity.

Balan I, Grusca A, Chéry SL, Materia BR, O'Buckley TK, Morrow AL
Life (Basel, Switzerland) 2024 Jul 9;14(7)

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DDX20 is required for cell-cycle reentry of prospermatogonia and establishment of spermatogonial stem cell pool during testicular development in mice.

Zou D, Li K, Su L, Liu J, Lu Y, Huang R, Li M, Mang X, Geng Q, Li P, Tang J, Yu Z, Zhang Z, Chen D, Miao S, Yu J, Yan W, Song W
Developmental cell 2024 Jul 8;59(13):1707-1723.e8

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CircCDC42-encoded CDC42-165aa regulates macrophage pyroptosis in Klebsiella pneumoniae infection through Pyrin inflammasome activation.

Xu N, Jiang J, Jiang F, Dong G, Meng L, Wang M, Chen J, Li C, Shi Y, He S, Li R
Nature communications 2024 Jul 8;15(1):5730

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Acid Neutralization by Composite Lysine Nanoparticles for Spinal Cord Injury Recovery through Mitigating Mitochondrial Dysfunction.

Wang Q, Ge L, Guo J, Zhang H, Chen T, Lian F, Li L, Xu Y, Xu J, Chen N, Zhang Y, Ruan Z, Xiao J, Zhang H, Yang L
ACS biomaterials science & engineering 2024 Jul 8;10(7):4480-4495

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Human cytomegalovirus infection impairs neural differentiation via repressing sterol regulatory element binding protein 2-mediated cholesterol biosynthesis.

Li J, Sun J, Xu M, Yang L, Yang N, Deng J, Ma Y, Qi Y, Liu Z, Ruan Q, Liu Y, Huang Y
Cellular and molecular life sciences : CMLS 2024 Jul 6;81(1):289

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Oridonin promotes RSL3-induced ferroptosis in breast cancer cells by regulating the oxidative stress signaling pathway JNK/Nrf2/HO-1.

Ye S, Hu X, Sun S, Su B, Cai J, Jiang J
European journal of pharmacology 2024 Jul 5;974:176620

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Genipin improves obesity through promoting bile secretion and changing bile acids composition in diet-induced obese rats.

Guan L, Zhang L, Gong D, Li P, Zhu S, Tang J, Du M, Zhang M, Zou Y
The Journal of pharmacy and pharmacology 2024 Jul 5;76(7):897-907

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GPR30 selective agonist G-1 induced insulin resistance in ovariectomized mice on high fat diet and its mechanism.

Lu C, Liu D, Li M, Shi X, Guan J, Song G, Yin Y, Zheng M, Ma F, Liu G
Biochemical and biophysical research communications 2024 Jul 5;716:150026

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Modified lentiviral globin gene therapy for pediatric β(0)/β(0) transfusion-dependent β-thalassemia: A single-center, single-arm pilot trial.

Li S, Ling S, Wang D, Wang X, Hao F, Yin L, Yuan Z, Liu L, Zhang L, Li Y, Chen Y, Luo L, Dai Y, Zhang L, Chen L, Deng D, Tang W, Zhang S, Wang S, Cai Y
Cell stem cell 2024 Jul 5;31(7):961-973.e8

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Exploring the Molecular Therapeutic Mechanisms of Gemcitabine through Quantitative Proteomics.

Jiang Y, Ren X, Zhao J, Liu G, Liu F, Guo X, Hao M, Liu H, Liu K, Huang H
Journal of proteome research 2024 Jul 5;23(7):2343-2354

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Phase separation of RNF214 promotes the progression of hepatocellular carcinoma.

He ZJ, He K, Cai SW, Zhang R, Shao ZB, Wang ST, Li XP, Li YC, Liu WJ, Zhu YQ, Zeng SJ, Su YB, Shi Z
Cell death & disease 2024 Jul 5;15(7):483

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Anti-hyperuricemia effect of Clerodendranthus spicatus: a molecular biology study combined with metabolomics.

Zhou Z, Xu M, Bian M, Nie A, Sun B, Zhu C
Scientific reports 2024 Jul 4;14(1):15449

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A Comparative Study of the Stability, Transport, and Structure-Activity Relationship of Round Scad Derived Peptides with Antineuroinflammatory Ability.

Zhang Q, Wang Y, Zhao L, Su G, Ding W, Zheng L, Zhao M
Journal of agricultural and food chemistry 2024 Jul 31;72(30):17017-17029

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High-intensity interval training improves hypothalamic inflammation by suppressing HIF-1α signaling in microglia of male C57BL/6J mice.

Chen Y, Zhang S, Ye L, Chen H, Ma P, Wu D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 31;38(14):e23770

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Single-cell transcriptome analysis revealed heterogeneity in glycolysis and identified IGF2 as a therapeutic target for ovarian cancer subtypes.

Ji J, Bi F, Zhang X, Zhang Z, Xie Y, Yang Q
BMC cancer 2024 Jul 31;24(1):926

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Esaxerenone Attenuates Aldosterone-Induced Mitochondrial Damage-Mediated Pyroptosis in Mouse Aorta and Rat Vascular Smooth Muscle Cells.

Xian Y, Wang X, Chang Y, Qiang P, Han Y, Hao J, Gao X, Shimosawa T, Xu Q, Yang F
Life (Basel, Switzerland) 2024 Jul 31;14(8)

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ATPR induces acute promyelocytic leukemia cells differentiation and cycle arrest via the lncRNA CONCR/DDX11/PML-RARα signaling axis.

Liu S, Zhan W, He X, Hao M, Shen W, Zhang X, Wang M, Li Z, Hou R, Ou Z, Feng Y, Chen F
Gene 2024 Jul 30;917:148443

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Exploring the Molecular Mechanism of Schisandrin C for the Treatment of Atherosclerosis via the PI3K/AKT/mTOR Autophagy Pathway.

Duan H, Li H, Liu T, Chen Y, Luo M, Shi Y, Zhou J, Rashed MMA, Zhai K, Li L, Wei Z
ACS omega 2024 Jul 30;9(30):32920-32930

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Lactylation of histone by BRD4 regulates astrocyte polarization after experimental subarachnoid hemorrhage.

Zhang F, Zhou J, Lu P, Zhang X, Yang L, Wu J, Zhang L, Zhang L, Pang J, Xie H, Xie B, Jiang Y, Peng J
Journal of neuroinflammation 2024 Jul 30;21(1):186

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Comprehensive analysis of circRNA-miRNA-mRNA network related to angiogenesis in recurrent implantation failure.

Wang A, Chen P
BMC medical genomics 2024 Jul 30;17(1):193

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Synergistic Efficacy of CDK4/6 Inhibitor Abemaciclib and HDAC Inhibitor Panobinostat in Pancreatic Cancer Cells.

Bhutkar S, Yadav A, Patel H, Barot S, Patel K, Dukhande VV
Cancers 2024 Jul 30;16(15)

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Echinatin alleviates inflammation and pyroptosis in hypoxic-ischemic brain damage by inhibiting TLR4/ NF-κB pathway.

Tao X, Hu Y, Mao N, Shen M, Fang M, Zhang M, Lou J, Fang Y, Guo X, Lin Z
International immunopharmacology 2024 Jul 30;136:112372

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SLC25A19 is a novel prognostic biomarker related to immune invasion and ferroptosis in HCC.

Liu S, Zhang P, Wu Y, Zhou H, Wu H, Jin Y, Wu D, Wu G
International immunopharmacology 2024 Jul 30;136:112367

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LDHA contributes to nicotine induced cardiac fibrosis through autophagy flux impairment.

Wu HH, Du JM, Liu P, Meng FL, Li YY, Li WJ, Wang SX, Du NL, Zheng Y, Zhang L, Wang HY, Liu YR, Song CH, Ni X, Li Y, Su GH
International immunopharmacology 2024 Jul 30;136:112338

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Berberine attenuates 5-fluorouracil-induced intestinal mucosal injury by modulating the gut microbiota without compromising its anti-tumor efficacy.

Wu C, Yang J, Ye C, Wu H, Shu W, Li R, Wang S, Lu Y, Chen H, Zhang Z, Yao Q
Heliyon 2024 Jul 30;10(14):e34528

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G protein-coupled receptor 91 promotes the inflammatory response to Porphyromonas gingivalis in bone marrow-derived macrophages.

Su W, Wang Y, Zu C, Lei L, Li H
Heliyon 2024 Jul 30;10(14):e34509

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Resistance training boosts lactate transporters and synaptic proteins in insulin-resistance mice.

Bian X, Li M, Lou S
Heliyon 2024 Jul 30;10(14):e34425

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Myeloid PTEN loss affects the therapeutic response by promoting stress granule assembly and impairing phagocytosis by macrophages in breast cancer.

Li Y, Xu C, Qian X, Wang G, Han C, Hua H, Dong M, Chen J, Yu H, Zhang R, Feng X, Yang Z, Pan Y
Cell death discovery 2024 Jul 30;10(1):344

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Stigmasterol Activates the mTOR Signaling Pathway by Inhibiting ORP5 Ubiquitination to Promote Milk Synthesis in Bovine Mammary Epithelial Cells.

Sun M, Cao Y, Cheng J, Xu D, Li F, Wang J, Ge Y, Liu Y, Long X, Guo W, Liu J, Fu S
Journal of agricultural and food chemistry 2024 Jul 3;72(26):14769-14785

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CCL2 promotes EGFR-TKIs resistance in non-small cell lung cancer via the AKT-EMT pathway.

Diao Y, Huang S, Liu F, Liao S, Guan C, Xiong X, Zhang P, Li J, Zhang W, Ying Y
Acta biochimica et biophysica Sinica 2024 Jul 3;56(10):1549-1560

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ZnO NPs induce miR-342-5p mediated ferroptosis of spermatocytes through the NF-κB pathway in mice.

Liu G, Lv J, Wang Y, Sun K, Gao H, Li Y, Yao Q, Ma L, Kochshugulova G, Jiang Z
Journal of nanobiotechnology 2024 Jul 3;22(1):390

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The Barrier Disruption and Pyroptosis of Intestinal Epithelial Cells Caused by Perfringolysin O (PFO) from Clostridium perfringens.

Liu Z, Mou S, Li L, Chen Q, Yang R, Guo S, Jin Y, Liu L, Li T, Chen H, Wang X
Cells 2024 Jul 3;13(13)

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Baicalin and probenecid protect against Glaesserella parasuis challenge in a piglet model.

Fu S, Liu S, Li J, Dong Q, Fu Y, Luo R, Sun Y, Tian X, Liu W, Zong B, Ye C, Lu Q, Qiu Y, Guo L
Veterinary research 2024 Jul 29;55(1):96

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Hydrogen Sulfide Promotes Platelet Autophagy via PDGFR-α/PI3K/Akt Signaling in Cirrhotic Thrombocytopenia.

Yang HX, Li YJ, He YL, Jin KK, Lyu LN, Ding HG
Journal of clinical and translational hepatology 2024 Jul 28;12(7):625-633

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EZH2-STAT3 signaling pathway regulates GSDMD-mediated pyroptosis in glioblastoma.

Yu D, Wang S, Wang J, Zhang K, Niu Z, Lin N
Cell death discovery 2024 Jul 28;10(1):341

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Adenosine kinase protects against acetaminophen-induced acute liver injury by activating autophagy in hepatocytes.

Zhang C, Liu X, Liu X, Hua R, Liu H, Ma J, Zou D, Wang G, Yuan Q, Wang B, Wei S, Chen Y
Cell biology and toxicology 2024 Jul 27;40(1):59

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Baicalin promotes the sensitivity of NSCLC to cisplatin by regulating ferritinophagy and macrophage immunity through the KEAP1-NRF2/HO-1 pathway.

Chen Y, Bao S, Wang Z, Fang Z, Tang H
European journal of medical research 2024 Jul 26;29(1):387

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The role of C5aR1-mediated hepatic macrophage efferocytosis in NASH.

Shen X, Zheng W, Du X, Chen Y, Song X, Yang L, Yuan Q
Scientific reports 2024 Jul 26;14(1):17232

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Transcription factor 7 like 2 promotes metastasis in hepatocellular carcinoma via NEDD9-mediated activation of AKT/mTOR signaling pathway.

Tang L, Xu S, Wei R, Fan G, Zhou J, Wei X, Xu X
Molecular medicine (Cambridge, Mass.) 2024 Jul 25;30(1):108

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Olanzapine suppresses mPFC activity-norepinephrine releasing to alleviate CLOCK-enhanced cancer stemness under chronic stress.

Lu J, Zhang X, Su K, Luo H, Liu C, Yang Y, He B, Wang C, Zhao Z, Liu X, Wang X, Meng P, Lv D, Wang C, Kelley KW, Wang L, Cui B, Liu Q, Peng F
Cell communication and signaling : CCS 2024 Jul 25;22(1):375

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KPNA2 promotes the progression of gastric cancer by regulating the alternative splicing of related genes.

Chen X, Wei H, Yue A, Zhang H, Zheng Y, Sun W, Zhou Y, Wang Y
Scientific reports 2024 Jul 25;14(1):17140

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Trilobatin suppresses aging-induced cognitive impairment by targeting SIRT2: Involvement of remodeling gut microbiota to mediate the brain-gut axis.

Xie DY, Lin M, Luo YM, Dong L, Wei Y, Gao JM, Zhu YZ, Gong QH
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155744

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Narirutin mitigates dextrose sodium sulfate-induced colitis in mice by modulating intestinal flora.

Xu D, Liu D, Jiang N, Xie Y, He D, Cheng J, Liu J, Fu S, Hu G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155730

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Zhen-wu-tang protects against myocardial fibrosis by inhibiting M1 macrophage polarization via the TLR4/NF-κB pathway.

Fang R, Zhou R, Ju D, Li M, Wang H, Pan L, Wang X, Han M, Yu Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155719

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Bruceine A alleviates alcoholic liver disease by inhibiting AIM2 inflammasome activation via activating FXR.

Li L, Xu S, Wang W, Li X, Wang H, Yang Q, Wang C, Gu J, Luo H, Meng Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155693

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Podophyllotoxin via SIRT1/PPAR /NF-κB axis induced cardiac injury in rats based on the toxicological evidence chain (TEC) concept.

Jiang T, Sun L, Wang Y, Zhang F, Guo J, Sun L, Jiang Y, Xue J, Duan J, Liu C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155655

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Quercetin inhibits neuronal Ferroptosis and promotes immune response by targeting lipid metabolism-related gene PTGS2 to alleviate breast cancer-related depression.

Zhu Q, Han Y, He Y, Meng P, Fu Y, Yang H, He G, Long M, Shi Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155560

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Ze-Qi-Tang formula inhibits MDSCs glycolysis through the down-regulation of p21/Hif1α/Glut1 signal in psoriatic-like mice.

Zhu Y, Chen X, Zou Y, Su L, Yan X, Zhu X, Hou Y, Liu M, Jiang W, Zou C, Chen X, Xu Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155544

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CircARAP2 controls sMICA-induced NK cell desensitization by erasing CTCF/PRC2-induced suppression in early endosome marker RAB5A.

Guo F, Du N, Wen X, Li Z, Guo Y, Zhou L, Hoffman AR, Li L, Hu JF, Cui J
Cellular and molecular life sciences : CMLS 2024 Jul 24;81(1):307

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Nervous necrosis virus capsid protein and Protein A dynamically modulate the fish cGAS-mediated IFN signal pathway to facilitate viral evasion.

Huang S, Yang L, Zheng R, Weng S, He J, Xie J
Journal of virology 2024 Jul 23;98(7):e0068624

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Fabrication of a Near-Infrared-Emissive Probe for Detecting Dipeptidyl Peptidase 4 in the Liver of Diabetic Mice and Clinical Serum.

Liu M, Zeng J, Zhang W, Lei J, Li S, Zhou J, Cheng D, He L
Analytical chemistry 2024 Jul 23;96(29):11890-11896

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Overexpression of transcription factor TBX5 inhibits the activation of YAP1-TEAD1 pathway to promote ferroptosis in lung cancer cells.

Ma R, Hu K, Dai S, Wang Y
Biochemical and biophysical research communications 2024 Jul 23;718:150037

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GM1 Ameliorates Neuronal Injury in Rats after Cerebral Ischemia and Reperfusion: Potential Contribution of Effects on SPTBN1-mediated Signaling.

Shi YW, Xu CC, Sun CY, Liu JX, Zhao SY, Liu D, Fan XJ, Wang CP
Neuroscience 2024 Jul 23;551:103-118

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β-catenin mediates monocrotaline-induced pulmonary hypertension via glycolysis in rats.

Meng H, Deng Y, Liao J, Wu DD, Li LX, Chen X, Lan WF
BMC cardiovascular disorders 2024 Jul 23;24(1):381

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PM2.5 triggers tau aggregation in a mouse model of tauopathy.

Liu C, Meng L, Gao Y, Chen J, Zhu M, Xiong M, Xiao T, Gu X, Liu C, Li T, Zhang Z
JCI insight 2024 Jul 22;9(14)

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Endothelial progenitor cells control remodeling of uterine spiral arteries for the establishment of utero-placental circulation.

Tan B, Lin L, Yuan Y, Long Y, Kang Y, Huang B, Huang LF, Li JH, Tong C, Qi HB
Developmental cell 2024 Jul 22;59(14):1842-1859.e12

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Molecular insights into degron recognition by CRL5(ASB7) ubiquitin ligase.

Zhou M, Wang X, Li J, Ma J, Bao Z, Yan X, Zhang B, Liu T, Yu Y, Mi W, Dong C
Nature communications 2024 Jul 22;15(1):6177

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Determining M2 macrophages content for the anti-tumor effects of metal-organic framework-encapsulated pazopanib nanoparticles in breast cancer.

Xu Z, Zhou Z, Yang X, Thakur A, Han N, Li HT, Li LG, Hu J, Li TF, Yan Y
Journal of nanobiotechnology 2024 Jul 20;22(1):429

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Oncogenic fatty acid oxidation senses circadian disruption in sleep-deficiency-enhanced tumorigenesis.

Peng F, Lu J, Su K, Liu X, Luo H, He B, Wang C, Zhang X, An F, Lv D, Luo Y, Su Q, Jiang T, Deng Z, He B, Xu L, Guo T, Xiang J, Gu C, Wang L, Xu G, Xu Y, Li M, Kelley KW, Cui B, Liu Q
Cell metabolism 2024 Jul 2;36(7):1598-1618.e11

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Intermittent hypoxia exacerbates anxiety in high-fat diet-induced diabetic mice by inhibiting TREM2-regulated IFNAR1 signaling.

Ni W, Niu Y, Cao S, Fan C, Fan J, Zhu L, Wang X
Journal of neuroinflammation 2024 Jul 2;21(1):166

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A novel variant in GAS2 is associated with autosomal dominant nonsyndromic hearing impairment in a Chinese family.

Zhang L, Zheng D, Xu L, Wang H, Zhang S, Shi J, Jin N
Human genomics 2024 Jul 2;18(1):73

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Depleting inositol pyrophosphate 5-InsP7 protected the heart against ischaemia-reperfusion injury by elevating plasma adiponectin.

Fu L, Du J, Furkert D, Shipton ML, Liu X, Aguirre T, Chin AC, Riley AM, Potter BVL, Fiedler D, Zhang X, Zhu Y, Fu C
Cardiovascular research 2024 Jul 2;120(8):954-970

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m6A-Mediated IRS1 Regulates the Development of Oral Squamous Cell Carcinoma through p53/Line-1 Signaling.

Xiao Y, Zhu X, Li Q, Wang Z, Zuo Q, Liu X, Tan J
Frontiers in bioscience (Landmark edition) 2024 Jul 19;29(7):257

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Pim-1 kinase protects the liver from ischemia reperfusion injury by regulating dynamics-related protein 1.

Sun YD, Xu QG, Dai DS, Wang SX, Li XQ, Shi SH, Jiang P, Jin Y, Wang X, Zhang Y, Wang F, Liu P, Zhang BL, Li TX, Xu CS, Wu B, Cai JZ
iScience 2024 Jul 19;27(7):110280

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Genetically modified pigs with CD163 point mutation are resistant to HP-PRRSV infection.

Liu Y, Yang L, Xiang HY, Niu M, Deng JC, Li XY, Hao WJ, Ou-Yang HS, Liu TY, Tang XC, Pang DX, Yuan HM
Zoological research 2024 Jul 18;45(4):833-844

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A novel cancer-associated fibroblasts risk score model predict survival and immunotherapy in lung adenocarcinoma.

Kong F, Lu Z, Xiong Y, Zhou L, Ye Q
Molecular genetics and genomics : MGG 2024 Jul 17;299(1):70

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Activation of the PERK/eIF2α axis is a pivotal prerequisite of taxanes to cancer cell apoptosis and renders synergism to overcome paclitaxel resistance in breast cancer cells.

Cai W, Rong D, Ding J, Zhang X, Wang Y, Fang Y, Xiao J, Yang S, Wang H
Cancer cell international 2024 Jul 17;24(1):249

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Cerium Vanadate Nanozyme with pH-Dependent Dual Enzymatic Activity for Glioblastoma Targeted Therapy and Postradiotherapy Damage Protection.

Han X, Li B, Wang W, Feng B, Tang Q, Qi Y, Zhao R, Qiu W, Zhao S, Pan Z, Guo X, Du H, Qiu J, Liu H, Li G, Xue H
ACS nano 2024 Jul 17;18(30):19836-53

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ZIF-8-based Nanoparticles for Inflammation Treatment and Oxidative Stress Reduction in Periodontitis.

Li Y, Xu C, Mao J, Mao L, Li W, Liu Z, Shin A, Wu J, Hou L, Li D, Lin K, Liu J
ACS applied materials & interfaces 2024 Jul 17;16(28):36077-36094

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m6A reader IGF2BP2 promotes M2 macrophage polarization and malignant biological behavior of bladder cancer by stabilizing NRP1 mRNA expression.

Fu D, Shi X, Yi X, Wu D, He H, Zhou W, Cheng W
BMC urology 2024 Jul 16;24(1):147

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Small molecule FICD inhibitors suppress endogenous and pathologic FICD-mediated protein AMPylation.

Chatterjee BK, Alam M, Chakravorty A, Lacy SM, Rech J, Brooks CL 3rd, Arvan PD, Truttmann MC
bioRxiv : the preprint server for biology 2024 Jul 16;

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Substrate specificity and protein stability drive the divergence of plant-specific DNA methyltransferases.

Jiang J, Gwee J, Fang J, Leichter SM, Sanders D, Ji X, Song J, Zhong X
bioRxiv : the preprint server for biology 2024 Jul 16;

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Fasudil attenuates oxidative stress-induced partial epithelial-mesenchymal transition of tubular epithelial cells in hyperuricemic nephropathy via activating Nrf2.

Cao Y, Wang Y, Li W, Feng J, Chen Y, Chen R, Hu L, Wei J
European journal of pharmacology 2024 Jul 15;975:176640

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Identification of activating transcription factor 6 (ATF6) as a novel prognostic biomarker and potential target in oral squamous cell carcinoma.

Wu Y, Xie Q, Wu L, Li Z, Li X, Zhang L, Zhang B
Gene 2024 Jul 15;915:148436

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Intermittent hypoxia exacerbates metabolic dysfunction-associated fatty liver disease by aggravating hepatic copper deficiency-induced ferroptosis.

Wang R, Lv Y, Ni Z, Feng W, Fan P, Wang Y, Lin Y, Chen X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23788

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Scutellarin alleviates renal ischemia-reperfusion injury by inhibiting the MAPK pathway and pro-inflammatory macrophage polarization.

Deng G, Zheng B, Dou M, Gao Y, Zhang X, Niu Z, Wei T, Han F, Ding C, Tian P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23769

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Hippocampal proteome comparison of infant and adult Fmr1 deficiency mice reveals adult-related changes associated with postsynaptic density.

Yang C, Huang YT, Yao YF, Fu JY, Long YS
Journal of proteomics 2024 Jul 15;303:105202

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Soluble Dietary Fiber of Hawthorn Relieves Constipation Induced by Loperamide Hydrochloride by Improving Intestinal Flora and Inflammation, Thereby Regulating the Aquaporin Ion Pathway in Mice.

Zhang H, Zu Q, Zhang J, Liu S, Zhang G, Chang X, Li X
Foods (Basel, Switzerland) 2024 Jul 15;13(14)

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The protective effects of aqueous extract of Schisandra sphenanthera against alcoholic liver disease partly through the PI3K-AKT-IKK signaling pathway.

Liu D, Yang K, Li T, Tang T, Wang Y, Wang W, Li J, Zhou P, Wang X, Zhao C, Guo D, Xie Y, Cheng J, Wang M, Sun J, Zhang X
Heliyon 2024 Jul 15;10(13):e34214

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Preliminary investigation of nitric oxide release from upconverted nanoparticles excited at 808 nm near-infrared for brain tumors.

Li L, Yang JH, Fa XM, Liu MS, Wang QL, Zeng TF, Chen RZ, Ou J, Xia XW
Heliyon 2024 Jul 15;10(13):e33576

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Comprehensive bioinformatics analysis and cell line experiments revealed the important role of CDCA3 in sarcoma.

Li Y, Wu Z, Ding T, Zhang W, Guo H, Huang F
Heliyon 2024 Jul 15;10(13):e32785

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The role of NAD-dependent deacetylase sirtuin-2 in liver metabolic stress through regulating pyruvate kinase M2 ubiquitination.

Guo J, Nie J, Li D, Zhang H, Zhao T, Zhang S, Ma L, Lu J, Ji H, Li S, Tao S, Xu B
Journal of translational medicine 2024 Jul 14;22(1):656

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The ubiquitin-like protein UBTD1 promotes colorectal cancer progression by stabilizing c-Myc to upregulate glycolysis.

Zhao L, Yu N, Zhai Y, Yang Y, Wang Y, Yang Y, Gong Z, Zhang Y, Zhang X, Guo W
Cell death & disease 2024 Jul 13;15(7):502

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Therapeutic potential of the secreted Kazal-type serine protease inhibitor SPINK4 in colitis.

Wang Y, Han J, Yang G, Zheng S, Zhou G, Liu X, Cao X, Li G, Zhang B, Xie Z, Li L, Zhang M, Li X, Chen M, Zhang S
Nature communications 2024 Jul 12;15(1):5874

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Discovery of a Covalent Inhibitor That Overcame Resistance to Venetoclax in AML Cells Overexpressing BFL-1.

Lou J, Zhou Q, Lyu X, Cen X, Liu C, Yan Z, Li Y, Tang H, Liu Q, Ding J, Lu Y, Huang H, Xie H, Zhao Y
Journal of medicinal chemistry 2024 Jul 11;67(13):10795-10830

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The ANGPTL4-HIF-1α loop: a critical regulator of renal interstitial fibrosis.

Li Y, Chen S, Yang Q, Liu X, Zhou W, Kang T, Wu W, Ou S
Journal of translational medicine 2024 Jul 11;22(1):649

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Ultrasound-responsive Bi(2)MoO(6)-MXene heterojunction as ferroptosis inducers for stimulating immunogenic cell death against ovarian cancer.

Cheng S, Zhou T, Luo Y, Zhang J, Dong K, Zhang Q, Shu W, Zhang T, Zhang Q, Shi R, Yao Y, Wang H
Journal of nanobiotechnology 2024 Jul 11;22(1):408

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AQP1 Deficiency Drives Phthalate-Induced Epithelial Barrier Disruption through Intestinal Inflammation.

Zhao Y, Hu ZY, Lou M, Jiang FW, Huang YF, Chen MS, Wang JX, Liu S, Shi YS, Zhu HM, Li JL
Journal of agricultural and food chemistry 2024 Jul 10;72(27):15334-15344

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BET Bromodomain Inhibition Potentiates Ocular Melanoma Therapy by Inducing Cell Cycle Arrest.

Chen X, Huang R, Zhang Z, Song X, Shen J, Wu Q
Investigative ophthalmology & visual science 2024 Jul 1;65(8):11

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Caveolin-1 scaffolding domain-derived peptide enhances erectile function by regulating oxidative stress, mitochondrial dysfunction, and apoptosis of corpus cavernosum smooth muscle cells in rats with cavernous nerve injury.

Xi Y, Feng Z, Xia T, Hong Y, Wu J, Chen J, Ge Y, Xiao H
Life sciences 2024 Jul 1;348:122694

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Adipocyte-specific disruption of the BBSome causes metabolic and autonomic dysfunction.

Zhao Y, Guo DF, Morgan DA, Cho YE, Rahmouni K
American journal of physiology. Regulatory, integrative and comparative physiology 2024 Jul 1;327(1):R54-R65

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Biphasic regulation of miR-17∼92 transcription during hypoxia: roles of HIF1 and p53 hyperphosphorylation at ser15.

Sun MR, Gonzalez S, Huang JB, Zhou Q, Cherukuri A, Adavadkar R, Yan HL, Sun SH, Zhou G, Raj JU, Chen T
American journal of physiology. Lung cellular and molecular physiology 2024 Jul 1;327(1):L102-L113

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Trailblazing in adjuvant research: succinate's uncharted territory with neutrophils.

Wang Y, Xiu Z, Qu K, Wang L, Wang H, Yu Y
American journal of physiology. Cell physiology 2024 Jul 1;327(1):C1-C10

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Inhibition of TREM-1 alleviates neuroinflammation by modulating microglial polarization via SYK/p38MAPK signaling pathway after traumatic brain injury.

Zhao T, Zhou Y, Zhang D, Han D, Ma J, Li S, Li T, Hu S, Li Z
Brain research 2024 Jul 1;1834:148907

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Study on the effect of protein lysine lactylation modification in macrophages on inhibiting periodontitis in rats.

Liu X, Wang J, Lao M, Liu F, Zhu H, Man K, Zhang J
Journal of periodontology 2024 Jan;95(1):50-63

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Single-Cell RNA Transcriptome of the Human Endometrium Reveals Epithelial Characterizations Associated with Recurrent Implantation Failure.

Zhang H, Zhang C, Zhang S
Advanced biology 2024 Jan;8(1):e2300110

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Allicin ameliorates sepsis-induced acute kidney injury through Nrf2/HO-1 signaling pathway.

Li XJ, Liu T, Wang Y
Journal of natural medicines 2024 Jan;78(1):53-67

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Soy isoflavone genistein attenuates the efficacy of immune checkpoint therapy in C57BL/6 mice inoculated with B16F1 melanoma and a high PD-L1 expression level reflects tumor resistance.

Yamamoto M, Tanaka Y, Takeda R, Nakamoto A, Nakamoto M, Yagita H, Sakai T
Journal of clinical biochemistry and nutrition 2024 Jan;74(1):57-62

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TAPI-1 Exhibits Anti-tumor Efficacy in Human Esophageal Squamous Cell Carcinoma Cells via Suppression of NF-κB Signaling Pathway.

Gao L, Li L, Zhang D, Qiu J, Qian J, Liu H
Digestive diseases and sciences 2024 Jan;69(1):81-94

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Mycobacterium tuberculosis PE_PGRS45 (Rv2615c) Promotes Recombinant Mycobacteria Intracellular Survival via Regulation of Innate Immunity, and Inhibition of Cell Apoptosis.

Xu T, Wang C, Li M, Wei J, He Z, Qian Z, Wang X, Wang H
Journal of microbiology (Seoul, Korea) 2024 Jan;62(1):49-62

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A novel AluYb8 insertion-associated non-coding RNA, lncMUTYH, impairs mitochondrial function and dampens the M2-like polarization of macrophages.

Dong G, Yin X, Liang Y, Chen J, Wang J, Jiang F, Wang C, Guo W, Wang Y
Free radical research 2024 Jan;58(1):27-42

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Muscle fibre transition and transcriptional changes of horse skeletal muscles during traditional Mongolian endurance training.

Bou T, Ding W, Ren X, Liu H, Gong W, Jia Z, Zhang X, Dugarjaviin M, Bai D
Equine veterinary journal 2024 Jan;56(1):178-192

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Hsa_circ_0001583 fuels bladder cancer metastasis by promoting staphylococcal nuclease and tudor domain containing 1-mediated MicroRNA decay.

Liu C, Cong Y, Chen L, Lv F, Cheng L, Song Y, Xing Y
Neoplasia (New York, N.Y.) 2024 Jan;47:100963

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PGAM5 exacerbates acute renal injury by initiating mitochondria-dependent apoptosis by facilitating mitochondrial cytochrome c release.

Li JY, Sun XA, Wang X, Yang NH, Xie HY, Guo HJ, Lu L, Xie X, Zhou L, Liu J, Zhang W, Lu LM
Acta pharmacologica Sinica 2024 Jan;45(1):125-136

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Inactivation of the TGF-β1/ALK5 axis enhances club cell function and alleviates lung tissue damage to ameliorate COPD progression through the MEK/ERK signaling pathway.

Tian J, Ouyang H, Wu J, Wen L, Li X, Yang F, Yuan H
General physiology and biophysics 2024 Jan;43(1):37-48

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Pb induces the release of CXCL10 and CCL2 chemokines via mtROS/NF-κB activation in BV-2 cells.

Jiang C, Li X, Xiang C, Ye F
Toxicology letters 2024 Jan;391:62-70

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Let-7a-5p abrogates progression of papillary thyroid carcinoma cells by decreasing nuclear receptor subfamily 6 group a member 1-mediated lipogenesis.

Zhao T, Sun J, Lu X, Liu L, Chen L, Zhao W, Zhou B
Journal of biochemical and molecular toxicology 2024 Jan;38(1):e23572

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Serum amyloid A aggravates endotoxin-induced ocular inflammation through the regulation of retinal microglial activation.

Feng H, Zhou W, Yang Y, Zhang X, Mao R, Zhou Y, Cheng T, Xiao H, Rao Y, He J, Zhao P, Li J, Jiang C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan;38(1):e23389

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CD30 plays a role in T-dependent immune response and T cell proliferation.

Cui D, Zhang Y, Chen L, Du H, Zheng B, Huang M, Li X, Wei J, Chen Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan;38(1):e23365

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Taxifolin-mediated Nrf2 activation ameliorates oxidative stress and apoptosis for the treatment of glucocorticoid-induced osteonecrosis of the femoral head.

Jiang H, Lin C, Cai T, Jiang L, Lou C, Lin S, Wang W, Yan Z, Pan X, Xue X
Phytotherapy research : PTR 2024 Jan;38(1):156-173

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PCB126 impairs human sperm functions by affecting post-translational modifications and mitochondrial functions.

Yang Y, Mei G, Yang L, Luo T, Wu R, Peng S, Peng Z, Cui J, Cheng Y
Chemosphere 2024 Jan;346:140532

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Ubiquitin ligase NEDD4 promotes the proliferation of hepatocellular carcinoma cells through targeting PCDH17 protein for ubiquitination and degradation.

Liu Z, Hu Q, Hu B, Cao K, Xu T, Hou T, Cao T, Wang R, Shi H, Zhang B
The Journal of biological chemistry 2024 Jan;300(1):105593

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SynCAM1 deficiency in the hippocampal parvalbumin interneurons contributes to sevoflurane-induced cognitive impairment in neonatal rats.

Zhao MM, Gu HW, Pan WT, Liu PM, Zhu TT, Shang HJ, Jia M, Yang JJ
CNS neuroscience & therapeutics 2024 Jan;30(1):e14554

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TRPC3 signalling contributes to the biogenesis of extracellular vesicles.

Padbury EH, Bálint Š, Carollo E, Carter DRF, Becker EBE
Journal of extracellular biology 2024 Jan;3(1):e132

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Prognostic value and immunological role of cathepsin S gene in pan‑cancer.

Liang S, Dang B, Chen S, Mi H
Oncology letters 2024 Jan;27(1):41

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Exosome‑delivered miR‑486‑3p inhibits the progression of osteosarcoma via sponging CircKEAP1/MARCH1 axis components.

Yang H, He C, Feng Y, Jin J
Oncology letters 2024 Jan;27(1):24

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Hematoporphyrin derivative photodynamic therapy induces apoptosis and suppresses the migration of human esophageal squamous cell carcinoma cells by regulating the PI3K/AKT/mTOR signaling pathway.

Wei X, Ni J, Yuan L, Li X
Oncology letters 2024 Jan;27(1):17

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Astragaloside IV promotes exosome secretion of endothelial progenitor cells to regulate PI3KR2/SPRED1 signaling and inhibit pyroptosis of diabetic endothelial cells.

Xiong W, Zhang X, Zhou J, Chen J, Liu Y, Yan Y, Tan M, Huang H, Si Y, Wei Y
Cytotherapy 2024 Jan;26(1):36-50

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Gut microbial metabolite facilitates colorectal cancer development via ferroptosis inhibition.

Cui W, Guo M, Liu D, Xiao P, Yang C, Huang H, Liang C, Yang Y, Fu X, Zhang Y, Liu J, Shi S, Cong J, Han Z, Xu Y, Du L, Yin C, Zhang Y, Sun J, Gu W, Chai R, Zhu S, Chu B
Nature cell biology 2024 Jan;26(1):124-137

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Oxidative stress is involved in immunosuppression and macrophage regulation in glioblastoma.

Liang X, Wang Z, Dai Z, Liu J, Zhang H, Wen J, Zhang N, Zhang J, Luo P, Liu Z, Liu Z, Cheng Q
Clinical immunology (Orlando, Fla.) 2024 Jan;258:109802

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Effects of hazelnut soluble dietary fiber on lipid-lowering and gut microbiota in high-fat-diet-fed rats.

Lin H, Li J, Sun M, Wang X, Zhao J, Zhang W, Lv G, Wang Y, Lin Z
International journal of biological macromolecules 2024 Jan;256(Pt 2):128538

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Grass carp superoxide dismutases exert antioxidant function and inhibit autophagy to promote grass carp reovirus (GCRV) replication.

Liang X, Wang Q, Wang H, Wang X, Chu P, Yang C, Li Y, Liao L, Zhu Z, Wang Y, He L
International journal of biological macromolecules 2024 Jan;256(Pt 2):128454

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Vasculogenic mimicry-associated novel gene signature predicted prognosis and response to immunotherapy in lung adenocarcinoma.

Zhang L, Wu J, Yin WW, Hu J, Liao L, Ma J, Xu Z, Wu S
Pathology, research and practice 2024 Jan;253:155048

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TESC acts as a prognostic factor and promotes epithelial-mesenchymal transition progression in esophageal squamous carcinoma.

Dong Y, Fan B, Li M, Zhang J, Xie S, Di S, Jia Q, Gong T
Pathology, research and practice 2024 Jan;253:154964

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NAMPT regulates mitochondria function and lipid metabolism during porcine oocyte maturation.

Guo X, Jiao L, Yi Y, Zhang HL, Liu YX, Wang ZY, Sun SC
Journal of cellular physiology 2024 Jan;239(1):180-192

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Hydrogen sulfide attenuates depression-like behaviours in Parkinson's disease model rats by improving synaptic plasticity in a hippocampal Warburg effect-dependent manner.

Liu F, Tian Q, Tang HL, Cheng X, Zou W, Zhang P
Pharmacology, biochemistry, and behavior 2024 Jan;234:173677

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Malonate differentially affects cell survival and confers chemoresistance in cancer cells via the induction of p53-dependent autophagy.

Cui H, Zhu B, Li H, Meng Y, Cai M, Wang H, Yuan M, Zhong X, Wang B, Shan H, Zhe Miao M, Chai K, Zheng J, Zhang L, Liu Y
Biochemical pharmacology 2024 Jan;219:115950

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Clemastine-induced enhancement of hippocampal myelination alleviates memory impairment in mice with chronic pain.

Zhu TT, Wang H, Liu PM, Gu HW, Pan WT, Zhao MM, Hashimoto K, Yang JJ
Neurobiology of disease 2024 Jan;190:106375

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Hepatocyte growth factor attenuates high glucose-disturbed mitochondrial dynamics in podocytes by decreasing ARF6-dependent DRP1 translocation.

Li Y, Li X, Yang Y, Li F, Chen Q, Zhao Z, Zhang N, Li H
Biochimica et biophysica acta. Molecular cell research 2024 Jan;1871(1):119623

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Myo6 mediates osteoclast function and is essential for joint damage in collagen-induced arthritis.

Tan H, Ma L, Qin T, Liu K, Liu Y, Wen C, You K, Pang C, Luo H, Wei L, Shu Y, Yang X, Shen X, Zhou C
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166902

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CARD9 deficiency aggravated nonalcoholic steatohepatitis in mice through increasing inflammatory response.

Liu X, Fang Y, Qian C, Chen J, Luo W, Zuo W, Lin J, Xie L, Liang G, Huang L, Wang Y
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166893

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Melatonin inhibits fibroblast cell functions and hypertrophic scar formation by enhancing autophagy through the MT2 receptor-inhibited PI3K/Akt /mTOR signaling.

Dong Y, Cao X, Huang J, Hu Z, Chen C, Chen M, Long Q, Xu Z, Lv D, Rong Y, Luo S, Wang H, Deng W, Tang B
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166887

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Eupatilin inhibits xanthine oxidase in vitro and attenuates hyperuricemia and renal injury in vivo.

Xu G, Wu L, Yang H, Liu T, Tong Y, Wan J, Han B, Zhou L, Hu X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Jan;183:114307

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6-Gingerol regulates triglyceride and cholesterol biosynthesis to improve hepatic steatosis in MAFLD by activating the AMPK-SREBPs signaling pathway.

Xia Q, Lu F, Chen Y, Li J, Huang Z, Fang K, Hu M, Guo Y, Dong H, Xu L, Gong J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:116060

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Berberine exerts antidepressant effects in vivo and in vitro through the PI3K/AKT/CREB/BDNF signaling pathway.

Tang Y, Su H, Nie K, Wang H, Gao Y, Chen S, Lu F, Dong H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:116012

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Exercise ameliorating myocardial injury in type 2 diabetic rats by inhibiting excessive mitochondrial fission involving increased irisin expression and AMP-activated protein kinase phosphorylation.

Wang B, Zhao C, Wang Y, Tian X, Lin J, Zhu B, Zhou Y, Zhang X, Li N, Sun Y, Xu H, Zhao R
Journal of diabetes 2024 Jan;16(1):e13475

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Brassisterol A, a new ergosterol from co-cultivation of fungi attenuates neuroinflammation via targeting NLRP3/caspase-1/GSDMD pathway.

Tong Z, Kong L, Zhang Y, Hu T, Dai R, Wang Y, Ji J, Huang Z, Hu L
Bioorganic chemistry 2024 Jan;142:106955

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ARID5B-mediated LINC01128 epigenetically activated pyroptosis and apoptosis by promoting the formation of the BTF3/STAT3 complex in β2GPI/anti-β2GPI-treated monocytes.

Tan Y, Qiao J, Yang S, Wang Q, Liu H, Liu Q, Feng W, Yang B, Li Z, Cui L
Clinical and translational medicine 2024 Jan;14(1):e1539

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The homologous tumor-derived-exosomes loaded with miR-1270 selectively enhanced the suppression effect for colorectal cancer cells.

Jin Y, Sun L, Chen Y, Lu Y
Cancer medicine 2024 Jan;13(1):e6936

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Taxifolin inhibits melanoma proliferation/migration impeding USP18/Rac1/JNK/β-catenin oncogenic signaling.

Xu L, Zhang L, Zhang S, Yang J, Zhu A, Sun J, Kalvakolanu DV, Cong X, Zhang J, Tang J, Guo B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155199

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QiShenYiQi pill inhibits atherosclerosis by promoting TTC39B-LXR mediated reverse cholesterol transport in liver.

Wang TT, Yang CY, Peng L, Li L, Chen NT, Feng X, Xie J, Wu TC, Xu T, Chen YZ
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155192

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Radix Astragali decoction improves liver regeneration by upregulating hepatic expression of aquaporin-9.

Li Y, Yang X, Bao T, Sun X, Li X, Zhu H, Zhang B, Ma T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155166

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Targeting HSP70 chaperones by rhein sensitizes liver cancer to artemisinin derivatives.

Wang J, Zhang J, Guo Z, Hua H, Zhang H, Liu Y, Jiang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155156

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Hyperoxia-induced airflow restriction and Renin-Angiotensin System expression in a bronchopulmonary dysplasia mouse model.

Dowell J, Bice Z, Yan K, Konduri GG
Physiological reports 2024 Jan;12(1):e15895

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Branched-Chain Amino Acid Accumulation Fuels the Senescence-Associated Secretory Phenotype.

Liang Y, Pan C, Yin T, Wang L, Gao X, Wang E, Quang H, Huang D, Tan L, Xiang K, Wang Y, Alexander PB, Li QJ, Yao TP, Zhang Z, Wang XF
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(2):e2303489

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let-7g sensitized liver cancer cells to 5-fluorouracil by downregulating ABCC10 expression.

Chen Y, Zhang B, Zhong C, Zhou Y, Xue L, Luo C, Yi L, Gong Q, Long Y
Chemical biology & drug design 2024 Jan;103(1):e14396

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Drp1 regulated PINK1-dependent mitophagy protected duck follicular granulosa cells from acute heat stress injury.

Yang C, Luo P, Yang YT, Fu XL, Li BX, Shen X, Xu DN, Huang YM, Tian YB, Liu WJ
Poultry science 2024 Jan;103(1):103247

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Resveratrol alleviates heat-stress-induced impairment of the jejunal mucosa through TLR4/MAPK signaling pathway in black-boned chicken.

Liu L, Gong X, Zhang X, Zhang D, Tang Y, Liu J, Li Y, Pan D
Poultry science 2024 Jan;103(1):103242

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MALAT1/miR-7-5p/TCF4 Axis Regulating Menstrual Blood Mesenchymal Stem Cells Improve Thin Endometrium Fertility by the Wnt Signaling Pathway.

Wang H, Chen K, Zong L, Zhao X, Wang J, Fan S, Shen B, Zheng S
Cell transplantation 2024 Jan-Dec;33:9636897241259552

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Time-restricted feeding ameliorates non-alcoholic fatty liver disease through modulating hepatic nicotinamide metabolism via gut microbiota remodeling.

Feng R, Yang W, Feng W, Huang X, Cen M, Peng G, Wu W, Wang Z, Jing Y, Long T, Liu Y, Li Z, Chang G, Huang K
Gut microbes 2024 Jan-Dec;16(1):2390164

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Gut microbiota regulates host melatonin production through epithelial cell MyD88.

Liu B, Fan L, Wang Y, Wang H, Yan Y, Chen S, Hung I, Liu C, Wei H, Ge L, Ren W
Gut microbes 2024 Jan-Dec;16(1):2313769

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SH3RF2 contributes to cisplatin resistance in ovarian cancer cells by promoting RBPMS degradation.

Gong TT, Liu FH, Xiao Q, Li YZ, Wei YF, Xu HL, Cao F, Sun ML, Jiang FL, Tao T, Ma QP, Qin X, Song Y, Gao S, Wu L, Zhao YH, Huang DH, Wu QJ
Communications biology 2024 Jan 9;7(1):67

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The E3 ligase NEURL3 suppresses epithelial-mesenchymal transition and metastasis in nasopharyngeal carcinoma by promoting vimentin degradation.

Zhou SQ, Feng P, Ye ML, Huang SY, He SW, Zhu XH, Chen J, Zhang Q, Li YQ
Journal of experimental & clinical cancer research : CR 2024 Jan 9;43(1):14

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Novel lissencephaly-associated NDEL1 variant reveals distinct roles of NDE1 and NDEL1 in nucleokinesis and human cortical malformations.

Tsai MH, Ke HC, Lin WC, Nian FS, Huang CW, Cheng HY, Hsu CS, Granata T, Chang CH, Castellotti B, Lin SY, Doniselli FM, Lu CJ, Franceschetti S, Ragona F, Hou PS, Canafoglia L, Tung CY, Lee MH, Wang WJ, Tsai JW
Acta neuropathologica 2024 Jan 9;147(1):13

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Prunella vulgaris polysaccharide inhibits herpes simplex virus infection by blocking TLR-mediated NF-κB activation.

Zhong X, Zhang Y, Yuan M, Xu L, Luo X, Wu R, Xi Z, Li Y, Xu H
Chinese medicine 2024 Jan 8;19(1):6

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Near-infrared-responsive GE11-CuS@Gal nanoparticles as an intelligent drug release system for targeting therapy against oral squamous cell carcinoma.

Lan Q, Wang S, Chen Z, Hua J, Hu J, Luo S, Xu Y
International journal of pharmaceutics 2024 Jan 5;649:123667

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Engineered exosomes mediated targeted delivery of neuroprotective peptide NR2B9c for the treatment of traumatic brain injury.

Haroon K, Zheng H, Wu S, Liu Z, Tang Y, Yang GY, Liu Y, Zhang Z
International journal of pharmaceutics 2024 Jan 5;649:123656

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Gestational exposure to 1-NP induces ferroptosis in placental trophoblasts via CYP1B1/ERK signaling pathway leading to fetal growth restriction.

Yu S, Mu Y, Wang K, Wang L, Wang C, Yang Z, Liu Y, Li S, Zhang M
Chemico-biological interactions 2024 Jan 5;387:110812

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Diosgenin alters LPS-induced macrophage polarization by activating PPARγ/NF-κB signaling pathway.

Xiang X, Xin X, Hou Y, Deng Y, Liu X, Yu W
International immunopharmacology 2024 Jan 5;126:111270

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Knockdown of Smox protects the integrity of the blood-brain barrier through antioxidant effect and Nrf2 pathway activation in stroke.

Wang G, Li Z, Lin P, Zhang H, Wang Y, Zhang T, Wang H, Li H, Lin L, Zhao Y, Jia L, Chen Y, Ji H, Zhao W, Fu Z, Zhong Z
International immunopharmacology 2024 Jan 5;126:111183

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A framework for Frizzled-G protein coupling and implications to the PCP signaling pathways.

Zhang Z, Lin X, Wei L, Wu Y, Xu L, Wu L, Wei X, Zhao S, Zhu X, Xu F
Cell discovery 2024 Jan 5;10(1):3

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TIMELESS promotes reprogramming of glucose metabolism in oral squamous cell carcinoma.

Chen Y, Han Z, Zhang L, Gao C, Wei J, Yang X, Han Y, Li Y, Zhang C, Wei Y, Dong J, Xun W, Sun W, Zhang T, Zhang H, Chen J, Yuan P
Journal of translational medicine 2024 Jan 4;22(1):21

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TET2-mediated tumor cGAS triggers endothelial STING activation to regulate vasculature remodeling and anti-tumor immunity in liver cancer.

Lv H, Zong Q, Chen C, Lv G, Xiang W, Xing F, Jiang G, Yan B, Sun X, Ma Y, Wang L, Wu Z, Cui X, Wang H, Yang W
Nature communications 2024 Jan 4;15(1):6

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Adipose-derived stem cell exosomes promote tumor characterization and immunosuppressive microenvironment in breast cancer.

Zhu Q, Cao Y, Yuan J, Hu Y
Cancer immunology, immunotherapy : CII 2024 Jan 31;73(2):39

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Methionine Promotes Milk Synthesis through the BRCC36-BRG1-mTOR Signaling Axis in Mammary Epithelial Cells.

Xie L, Li R, Zhang J, Li H, Gao X, Zhang M
Journal of agricultural and food chemistry 2024 Jan 31;72(4):2135-2144

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A network pharmacology approach and experimental validation to investigate the anticancer mechanism of Qi-Qin-Hu-Chang formula against colitis-associated colorectal cancer through induction of apoptosis via JNK/p38 MAPK signaling pathway.

Wu Y, Fang Y, Li Y, Au R, Cheng C, Li W, Xu F, Cui Y, Zhu L, Shen H
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117323

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Huaier suppresses cisplatin resistance in non-small cell lung cancer by inhibiting the JNK/JUN/IL-8 signaling pathway.

Jin H, Liu C, Liu X, Wang H, Zhang Y, Liu Y, Li J, Yu Z, Liu HX
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117270

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Prunella vulgaris L. attenuates gut dysbiosis and endotoxin leakage against alcoholic liver disease.

Rao PL, Shen YH, Song YJ, Xu Y, Xu HX
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117237

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The protective effect of apolipoprotein H in paediatric sepsis.

Yu Z, Xiao C, Liu R, Pi D, Jin B, Zou Z, Xu F
Critical care (London, England) 2024 Jan 30;28(1):36

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A peptide from the Japanese encephalitis virus failed to induce the production of anti-N-methyl-d-aspartate receptor antibodies via molecular mimicry in mice.

Luo H, Yang J, Yang X, Han Z, Fang Z, Huang D, Gui J, Ding R, Chen H, Cheng L, Ma J, Jiang L
Heliyon 2024 Jan 30;10(2):e24700

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Huc-MSC-derived exosomal miR-144 alleviates inflammation in LPS-induced preeclampsia-like pregnant rats via the FosB/Flt-1 pathway.

Sun J, Zhang W
Heliyon 2024 Jan 30;10(2):e24575

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TET2-mediated ECM1 hypomethylation promotes the neovascularization in active proliferative diabetic retinopathy.

Cai C, Gu C, He S, Meng C, Lai D, Zhang J, Qiu Q
Clinical epigenetics 2024 Jan 3;16(1):6

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Porcine Intestinal Mucosal Peptides Target Macrophage-Modulated Inflammation and Alleviate Intestinal Homeostasis in Dextrose Sodium Sulfate-Induced Colitis in Mice.

Wang Y, Xie Z, Wu X, Du L, Chong Z, Liu R, Han J
Foods (Basel, Switzerland) 2024 Jan 3;13(1)

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Antioxidative Sirt1 and the Keap1-Nrf2 Signaling Pathway Impair Inflammation and Positively Regulate Autophagy in Murine Mammary Epithelial Cells or Mammary Glands Infected with Streptococcus uberis.

Khan S, Wang T, Cobo ER, Liang B, Khan MA, Xu M, Qu W, Gao J, Barkema HW, Kastelic JP, Liu G, Han B
Antioxidants (Basel, Switzerland) 2024 Jan 29;13(2)

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Deciphering the tumor-suppressive role of PSMB9 in melanoma through multi-omics and single-cell transcriptome analyses.

Hu X, Hu Z, Zhang H, Zhang N, Feng H, Jia X, Zhang C, Cheng Q
Cancer letters 2024 Jan 28;581:216466

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Phosphorylated α-synuclein deposited in Schwann cells interacting with TLR2 mediates cell damage and induces Parkinson's disease autonomic dysfunction.

Li Y, Tong Q, Wang Y, Cheng Y, Geng Y, Tian T, Yuan Y, Fan Y, Lu M, Zhang K
Cell death discovery 2024 Jan 26;10(1):52

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Endoplasmic reticulum aminopeptidase 2 regulates CD4(+) T cells pyroptosis in rheumatoid arthritis.

Zhang J, Cai H, Sun W, Wu W, Nan Y, Ni Y, Wu X, Chen M, Xu H, Wang Y
Arthritis research & therapy 2024 Jan 25;26(1):36

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SHMT2 promotes papillary thyroid cancer metastasis through epigenetic activation of AKT signaling.

Sun M, Zhao M, Li R, Zhang Y, Shi X, Ding C, Ma C, Lu J, Yue X
Cell death & disease 2024 Jan 25;15(1):87

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Morroniside-mediated mitigation of stem cell and endothelial cell dysfunction for the therapy of glucocorticoid-induced osteonecrosis of the femoral head.

Jiang H, Wang W, Mao Y, Jiang L, Yu J, Zhu X, Fu H, Lin Z, Shen H, Pan X, Xue X
International immunopharmacology 2024 Jan 25;127:111421

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Gypenoside XLIX attenuates sepsis-induced splenic injury through inhibiting inflammation and oxidative stress.

Xu B, Yang R, Qiang J, Xu X, Zhou M, Ji X, Lu Y, Dong Z
International immunopharmacology 2024 Jan 25;127:111420

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TDP43/HDAC6/Prdx1 signaling pathway participated in the cognitive impairment of obstructive sleep apnea via regulating inflammation and oxidative stress.

Ou Y, Shen C, Chen Z, Liu T, Peng Y, Zong D, Ouyang R
International immunopharmacology 2024 Jan 25;127:111350

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Panax notoginseng saponin R1 improves glucocorticoid-inhibited airway epithelium repair via glucocorticoid receptor β.

Yang L, Xu M, Zhang L, Zhang M, Wu W, Luo Z, Tian D, Fu Z, Zou W
International immunopharmacology 2024 Jan 25;127:111347

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Cold-inducible RNA-binding protein induces inflammatory responses via NF-κB signaling pathway in normal human bronchial epithelial cells infected with streptococcus pneumoniae.

Zhang R, Fang K, Mu C, Zhang L
International immunopharmacology 2024 Jan 25;127:111338

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METTL1 mediated tRNA m(7)G modification promotes leukaemogenesis of AML via tRNA regulated translational control.

Zhao P, Xia L, Chen D, Xu W, Guo H, Xu Y, Yan B, Wu X, Li Y, Zhang Y, Zhang X
Experimental hematology & oncology 2024 Jan 24;13(1):8

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Pseudorabies virus upregulates low-density lipoprotein receptors to facilitate viral entry.

Ma Y-X, Chai Y-J, Han Y-Q, Zhao S-B, Yang G-Y, Wang J, Ming S-L, Chu B-B
Journal of virology 2024 Jan 23;98(1):e0166423

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Integrin β1-rich extracellular vesicles of kidney recruit Fn1+ macrophages to aggravate ischemia-reperfusion-induced inflammation.

Wang W, Ren X, Chen X, Hong Q, Cai G
JCI insight 2024 Jan 23;9(2)

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Exogenous carbon monoxide promotes GPX4-dependent ferroptosis through ROS/GSK3β axis in non-small cell lung cancer.

Cao W, Sun M, Yu KN, Zhao L, Feng Y, Tan C, Yang M, Wang Y, Zhu F, Chen L, Nie L, Zhao Y, Chen G, Han W
Cell death discovery 2024 Jan 23;10(1):42

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miR-4687-5p Affects Intracellular Survival of Mycobacterium tuberculosis through Its Regulation of NRAMP1 Expression in A549 Cells.

Meng C, Chen G, Liu Y, Wen D, Cui J, Dong L, Yang Z, Meng H, Gao Y, Feng J, Cui X, Wu C
Microorganisms 2024 Jan 22;12(1)

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LDLR is used as a cell entry receptor by multiple alphaviruses.

Zhai X, Li X, Veit M, Wang N, Wang Y, Merits A, Jiang Z, Qin Y, Zhang X, Qi K, Jiao H, He WT, Chen Y, Mao Y, Su S
Nature communications 2024 Jan 20;15(1):622

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Targeting gut microbial nitrogen recycling and cellular uptake of ammonium to improve bortezomib resistance in multiple myeloma.

Zhu Y, Jian X, Chen S, An G, Jiang D, Yang Q, Zhang J, Hu J, Qiu Y, Feng X, Guo J, Chen X, Li Z, Zhou R, Hu C, He N, Shi F, Huang S, Liu H, Li X, Xie L, Zhu Y, Zhao L, Jiang Y, Li J, Wang J, Qiu L, Chen X, Jia W, He Y, Zhou W
Cell metabolism 2024 Jan 2;36(1):159-175.e8

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Pharmaceutical targeting of OTUB2 sensitizes tumors to cytotoxic T cells via degradation of PD-L1.

Ren W, Xu Z, Chang Y, Ju F, Wu H, Liang Z, Zhao M, Wang N, Lin Y, Xu C, Chen S, Rao Y, Lin C, Yang J, Liu P, Zhang J, Huang C, Xia N
Nature communications 2024 Jan 2;15(1):9

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FOXP3(+) regulatory T cell perturbation mediated by the IFNγ-STAT1-IFITM3 feedback loop is essential for anti-tumor immunity.

Liu X, Zhang W, Han Y, Cheng H, Liu Q, Ke S, Zhu F, Lu Y, Dai X, Wang C, Huang G, Su B, Zou Q, Li H, Zhao W, Xiao L, Lu L, Tong X, Pan F, Li H, Li B
Nature communications 2024 Jan 2;15(1):122

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YTHDF3 modulates the Cbln1 level by recruiting BTG2 and is implicated in the impaired cognition of prenatal hypoxia offspring.

Lu L, Shi Y, Wei B, Li W, Yu X, Zhao Y, Yu D, Sun M
iScience 2024 Jan 19;27(1):108703

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Hexamethylene amiloride synergizes with venetoclax to induce lysosome-dependent cell death in acute myeloid leukemia.

Jiang X, Huang K, Sun X, Li Y, Hua L, Liu F, Huang R, Du J, Zeng H
iScience 2024 Jan 19;27(1):108691

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Chromatin target of protein arginine methyltransferases alleviates cerebral ischemia/reperfusion-induced injury by regulating RNA alternative splicing.

Cui Y, Zhang Z, Lv M, Duan Z, Liu W, Gao J, Xu R, Wan Q
iScience 2024 Jan 19;27(1):108688

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Phosphorylation-dependent membraneless organelle fusion and fission illustrated by postsynaptic density assemblies.

Wu H, Chen X, Shen Z, Li H, Liang S, Lu Y, Zhang M
Molecular cell 2024 Jan 18;84(2):309-326.e7

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Loss of LBP triggers lipid metabolic disorder through H3K27 acetylation-mediated C/EBPβ- SCD activation in non-alcoholic fatty liver disease.

Zhu YL, Meng LL, Ma JH, Yuan X, Chen SW, Yi XR, Li XY, Wang Y, Tang YS, Xue M, Zhu MZ, Peng J, Lu XJ, Huang JZ, Song ZC, Wu C, Zheng KZ, Dai QQ, Huang F, Fang HS
Zoological research 2024 Jan 18;45(1):79-94

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MTFR2-dependent mitochondrial fission promotes HCC progression.

Zhang L, Zhang X, Liu H, Yang C, Yu J, Zhao W, Guo J, Zhou B, Jiang N
Journal of translational medicine 2024 Jan 18;22(1):73

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The SIRT1/Nrf2 signaling pathway mediates the anti-pulmonary fibrosis effect of liquiritigenin.

Hua Q, Ren L
Chinese medicine 2024 Jan 18;19(1):12

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Metabolic regulation of homologous recombination repair by MRE11 lactylation.

Chen Y, Wu J, Zhai L, Zhang T, Yin H, Gao H, Zhao F, Wang Z, Yang X, Jin M, Huang B, Ding X, Li R, Yang J, He Y, Wang Q, Wang W, Kloeber JA, Li Y, Hao B, Zhang Y, Wang J, Tan M, Li K, Wang P, Lou Z, Yuan J
Cell 2024 Jan 18;187(2):294-311.e21

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Transcription factor Sp1 transcriptionally enhances GSDME expression for pyroptosis.

Pan J, Li Y, Gao W, Jiang Q, Geng L, Ding J, Li S, Li J
Cell death & disease 2024 Jan 18;15(1):66

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USP29 activation mediated by FUBP1 promotes AURKB stability and oncogenic functions in gastric cancer.

Tu R, Kang Y, Pan Y, Da Y, Ren D, Zhang R, Cai Z, Liu Y, Xu J, Ma J, Zhou Z, Yin S, Li X, Zhang P, Zhang Q, Wang J, Lu X, Zhang C
Cancer cell international 2024 Jan 17;24(1):33

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Egr-1 is a key regulator of the blood-brain barrier damage induced by meningitic Escherichia coli.

Yang R, Wang X, Liu H, Chen J, Tan C, Chen H, Wang X
Cell communication and signaling : CCS 2024 Jan 17;22(1):44

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c-Fos regulated by TMPO/ERK axis promotes 5-FU resistance via inducing NANOG transcription in colon cancer.

Gui Y, Qian X, Ding Y, Chen Q, Fangyu Ye, Ye Y, Hou Y, Yu J, Zhao L
Cell death & disease 2024 Jan 17;15(1):61

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Antitumor Effect of Platinum-Modified STING Agonist MSA-2.

Wang M, Cai Y, He T, Zhang Y, Yi L, Li W, Zhou P
ACS omega 2024 Jan 16;9(2):2650-2656

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MicroRNA-218-5p-Ddx41 axis restrains microglia-mediated neuroinflammation through downregulating type I interferon response in a mouse model of Parkinson's disease.

Wang D, Gao H, Qin Q, Li J, Zhao J, Qu Y, Li J, Xiong Y, Min Z, Mao Z, Xue Z
Journal of translational medicine 2024 Jan 16;22(1):63

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A functional mini-GDE transgene corrects impairment in models of glycogen storage disease type III.

Gardin A, Rouillon J, Montalvo-Romeral V, Rossiaud L, Vidal P, Launay R, Vie M, Krimi Benchekroun Y, Cosette J, Bertin B, La Bella T, Dubreuil G, Nozi J, Jauze L, Fragnoud R, Daniele N, Van Wittenberghe L, Esque J, André I, Nissan X, Hoch L, Ronzitti G
The Journal of clinical investigation 2024 Jan 16;134(2)

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Cell surface GRP78: A potential therapeutic target for high glucose-induced endothelial injury.

Wang B, He X, Zhang J, Zhang Y
Biochemical and biophysical research communications 2024 Jan 15;692:149347

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Characterization and verification of CD81 as a potential target in lung squamous cell carcinoma.

Ye X, Deng J, Dong C, Pan X, Lu Y
Biochemical and biophysical research communications 2024 Jan 15;692:149344

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Resveratrol protected against the development of endometriosis by promoting ferroptosis through miR-21-3p/p53/SLC7A11 signaling pathway.

Zou W, Wang X, Xia X, Zhang T, Nie M, Xiong J, Fang X
Biochemical and biophysical research communications 2024 Jan 15;692:149338

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Cadmium exposure induces pyroptosis of TM4 cells through oxidative stress damage and inflammasome activation.

Zhou J, Zhang Y, Zeng L, Wang X, Xiang W, Su P
Ecotoxicology and environmental safety 2024 Jan 15;270:115930

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Mitochondrial targeting derivatives of honokiol enhanced selective antitumor activity in NCI-H446 cells and decreased in vivo toxicity in Caenorhabditis elegans.

Miao H, Cui W, Zhang T, Zhang Y, Zhang J, Lou H, Fan P
European journal of medicinal chemistry 2024 Jan 15;264:115996

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Celastrol-loaded bovine serum albumin nanoparticles target inflamed neutrophils for improved rheumatoid arthritis therapy.

Liu S, Liu M, Xiu J, Zhang T, Zhang B, Cun D, Yang C, Li K, Zhang J, Zhao X
Acta biomaterialia 2024 Jan 15;174:345-357

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Spliceosome component PHD finger 5A is essential for early B lymphopoiesis.

Zhang R, Wang D, Ruan GX, Wang R, Li Y, Chen W, Huang H, Wang J, Meng L, Zhu Z, Lei D, Xu S, Ou X
Development (Cambridge, England) 2024 Jan 15;151(2)

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Multi-monoubiquitylation controls VASP-mediated actin dynamics.

McCormick LE, Suarez C, Herring LE, Cannon KS, Kovar DR, Brown NG, Gupton SL
Journal of cell science 2024 Jan 15;137(2)

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MicroRNA-146a-loaded magnesium silicate nanospheres promote bone regeneration in an inflammatory microenvironment.

Yang J, Shuai J, Siow L, Lu J, Sun M, An W, Yu M, Wang B, Chen Q
Bone research 2024 Jan 15;12(1):2

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Identification and Validation of a Prognostic Signature Derived from the Cancer Stem Cells for Oral Squamous Cell Carcinoma.

Shi M, Huang K, Wei J, Wang S, Yang W, Wang H, Li Y
International journal of molecular sciences 2024 Jan 14;25(2)

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From Hit to Lead: Structure-Based Optimization of Novel Selective Inhibitors of Receptor-Interacting Protein Kinase 1 (RIPK1) for the Treatment of Inflammatory Diseases.

Zhang L, Li Y, Tian C, Yang R, Wang Y, Xu H, Zhu Q, Chen S, Li L, Yang S
Journal of medicinal chemistry 2024 Jan 11;67(1):754-773

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PHB2 promotes SHIP2 ubiquitination via the E3 ligase NEDD4 to regulate AKT signaling in gastric cancer.

Xu L, Xiang W, Yang J, Gao J, Wang X, Meng L, Ye K, Zhao XH, Zhang XD, Jin L, Ye Y
Journal of experimental & clinical cancer research : CR 2024 Jan 11;43(1):17

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Gentiopicroside inhibits the progression of gastric cancer through modulating EGFR/PI3K/AKT signaling pathway.

Chen Q, Zhang T, Li B, Zhu Z, Ma X, Zhang Y, Li L, Zhu J, Zhang G
European journal of medical research 2024 Jan 11;29(1):47

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Orange-spotted grouper nervous necrosis virus-encoded protein A induces interferon expression via RIG-I/MDA5-MAVS-TBK1-IRF3 signaling in fish cells.

Huang S, Huang Y, Su T, Huang R, Su L, Wu Y, Weng S, He J, Xie J
Microbiology spectrum 2024 Jan 11;12(1):e0453222

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Podophyllotoxin-mediated neurotoxicity via the microbiota-gut-brain axis in SD rats based on the toxicological evidence chain (TEC) concept.

Duan J, Sun J, Jiang T, Ma X, Li X, Wang Y, Zhang F, Liu C
The Science of the total environment 2024 Jan 10;907:168106

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Acylated Ghrelin Activates PI3K/mTOR Signaling Pathway by Promoting ThPOK Acetylation to Promote Milk Fat Synthesis in Bovine Mammary Epithelial Cells.

Wang J, Cao Y, Long X, Li F, Jiang N, Sun M, Xie Y, Ge Y, Guo W, Liu J, Fu S
Journal of agricultural and food chemistry 2024 Jan 10;72(1):390-404

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Chinese herbal medicine alleviates autophagy and apoptosis in ovarian granulosa cells induced by testosterone through PI3K/AKT1/FOXO1 pathway.

Hu W, Xie N, Pan M, Zhang Q, Zhang H, Wang F, Qu F
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117025

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Xiaobanxia decoction alleviates chemotherapy-induced nausea and vomiting by inhibiting GSDME-mediated pyroptosis.

Liao X, Ye B, Hu W, Han J, Zhao Y, Dai Y, Wu X, Mo Z, Wei L, Nie K
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):116970

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Inhibitory effect of Lonicera japonica-derived exosomal miR2911 on human papilloma virus.

Chi Y, Shi L, Lu S, Cui H, Zha W, Shan L, Shen Y
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):116969

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Xiao-Ban-Xia decoction mitigates cisplatin-induced emesis via restoring PINK1/Parkin mediated mitophagy deficiency in a rat pica model.

Zhao Y, Han J, Hu W, Dai Y, Wu X, Liao X, Zhou H, Nie K
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116882

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ETV7 promotes colorectal cancer progression through upregulation of IFIT3.

Chai B, Li Y, Guo Y, Zhang Z, Jia K, Chai X, Suo Y
Functional & integrative genomics 2024 Jan 10;24(1):8

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ALCAT1-mediated abnormal cardiolipin remodelling promotes mitochondrial injury in podocytes in diabetic kidney disease.

Hao Y, Fan Y, Feng J, Zhu Z, Luo Z, Hu H, Li W, Yang H, Ding G
Cell communication and signaling : CCS 2024 Jan 10;22(1):26

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PFKFB3 promotes endometriosis cell proliferation via enhancing the protein stability of β-catenin.

Ling X, Liu L, Jiang A, Shi X, Liu L, Wang X, Lu C, Ren C, Yu Z
Molecular and cellular endocrinology 2024 Jan 1;579:112083

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Blocking the interaction between circTNRC18 and LIN28A promotes trophoblast epithelial-mesenchymal transformation and alleviates preeclampsia.

Chen LL, Li YQ, Kang ZH, Zhang X, Gu SY, Wang N, Shen XY
Molecular and cellular endocrinology 2024 Jan 1;579:112073

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Proteomics analysis of serum and urine identifies VCP and CTSA as potential biomarkers associated with multiple myeloma.

Fu W, Song Y, Zhao R, Zhao J, Yue Y, Zhang R
Clinica chimica acta; international journal of clinical chemistry 2024 Jan 1;552:117701

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Aging-related NOX4-Nrf2 redox imbalance increases susceptibility to cisplatin-induced acute kidney injury by regulating mitophagy.

Hu J, Hou W, Ma N, Zhang Y, Liu X, Wang Y, Ci X
Life sciences 2024 Jan 1;336:122352

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Parkin-mediated mitophagy is a potential treatment for oxaliplatin-induced peripheral neuropathy.

Zhao G, Zhang T, Li J, Li L, Chen P, Zhang C, Li K, Cui C
American journal of physiology. Cell physiology 2024 Jan 1;326(1):C214-C228

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Low beauvericin concentrations promote PC-12 cell survival under oxidative stress by regulating lipid metabolism and PI3K/AKT/mTOR signaling.

Hu L, Sui X, Dong X, Li Z, Lun S, Wang S
Ecotoxicology and environmental safety 2024 Jan 1;269:115786

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Synergistic anticancer effect by targeting CDK2 and EGFR-ERK signaling.

Wu J, Chen Y, Li R, Guan Y, Chen M, Yin H, Yang X, Jin M, Huang B, Ding X, Yang J, Wang Z, He Y, Wang Q, Luo J, Wang P, Mao Z, Huen MSY, Lou Z, Yuan J, Gong F
The Journal of cell biology 2024 Jan 1;223(1)

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Proteolysis Targeting Chimeras (PROTACs) based on celastrol induce multiple protein degradation for triple-negative breast cancer treatment.

Gan X, Wang F, Luo J, Zhao Y, Wang Y, Yu C, Chen J
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2024 Jan 1;192:106624

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Effect of vitrification on protein O-GlcNAcylation in mouse metaphase II oocytes.

Zhang K, Lan T, Lin F, Liu R, He Q, Gao F, Wu S, Kang J, Li H, Quan F
Reproduction (Cambridge, England) 2024 Jan 1;167(1)

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Rapid turnover of CTLA4 is associated with a complex architecture of reversible ubiquitylation.

Tey PY, Dufner A, Knobeloch KP, Pruneda JN, Clague MJ, Urbé S
bioRxiv : the preprint server for biology 2024 Jan 1;

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The E3 ubiquitin ligase TRIM9 regulates synaptic function and actin dynamics.

McCormick LE, Evans EB, Barker NK, Herring LE, Diering GH, Gupton SL
bioRxiv : the preprint server for biology 2024 Jan 1;

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Demethylase FTO-Mediated m6A Modification of lncRNA MEG3 Activates Neuronal Pyroptosis via NLRP3 Signaling in Cerebral Ischemic Stroke.

Yan H, Huang W, Rao J, Yan D, Yuan J
Molecular neurobiology 2024 Feb;61(2):1023-1043

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LncRNA JHDM1D-AS1 promotes osteogenic differentiation of periodontal ligament cells by targeting miR-532-5p to activate IGF1R signaling.

Zhong X, Wang H
Journal of periodontal research 2024 Feb;59(1):220-230

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Omega-3 polyunsaturated fatty acids and its metabolite 12-HEPE rescue busulfan disrupted spermatogenesis via target to GPR120.

Jing J, Ouyang L, Zhang H, Liang K, Ma R, Ge X, Tang T, Zhao S, Xue T, Shen J, Ma J, Li Z, Wu J, Yang Y, Zhao W, Zheng L, Qian Z, Sun S, Ge Y, Chen L, Li C, Yao B
Cell proliferation 2024 Feb;57(2):e13551

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Pyruvate kinase M2 regulates kidney fibrosis through pericyte glycolysis during the progression from acute kidney injury to chronic kidney disease.

Chen Y, Bai X, Chen J, Huang M, Hong Q, Ouyang Q, Sun X, Zhang Y, Liu J, Wang X, Wu L, Chen X
Cell proliferation 2024 Feb;57(2):e13548

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Helicobacter pylori CagA-mediated ether lipid biosynthesis promotes ferroptosis susceptibility in gastric cancer.

Peng Y, Lei X, Yang Q, Zhang G, He S, Wang M, Ling R, Zheng B, He J, Chen X, Li F, Zhou Q, Zhao L, Ye G, Li G
Experimental & molecular medicine 2024 Feb;56(2):441-452

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A Study on the Acquisition and Identification of Beige Adipocytes and Exosomes as Well as Their Inflammatory Regulation by Promoting Macrophage Polarization.

Wu B, Cen W, Liu C, Wang T, Wei J, Wang S, Zhang D, Li C
Aesthetic plastic surgery 2024 Feb;48(3):519-529

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Overexpressed FAM111B degrades GSDMA to promote esophageal cancer tumorigenesis and cisplatin resistance.

Wang H, Wang H, Chen J, Liu P, Xiao X
Cellular oncology (Dordrecht, Netherlands) 2024 Feb;47(1):343-359

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NQO1 Mediates Lenvatinib Resistance by Regulating ROS-induced Apoptosis in Hepatocellular Carcinoma.

Xue W, Wang T, Tian WJ, Pang SQ, Zhang HF, Jia WD
Current medical science 2024 Feb;44(1):168-179

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Synergistic effect of adavosertib and fimepinostat on acute myeloid leukemia cells by enhancing the induction of DNA damage.

Wang Y, Lin X, Wang Y, Wang G
Investigational new drugs 2024 Feb;42(1):70-79

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The protein kinase A signaling pathway mediates the effect of electroacupuncture on excessive contraction of the bladder detrusor in a rat model of neurogenic bladder.

Liu Q, Qu QR, Xu M, Liu JS, Qi F, Yi XQ, Zhang H, Zhou L, Ai K
Acupuncture in medicine : journal of the British Medical Acupuncture Society 2024 Feb;42(1):32-38

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Hsp90 β is critical for the infection of severe fever with thrombocytopenia syndrome virus.

Wang B, Zhang L, Deng F, Hu Z, Wang M, Liu J
Virologica Sinica 2024 Feb;39(1):113-122

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The role and mechanism of RIPK1 in vascular endothelial dysfunction in chronic kidney disease.

Wang C, Chen H, Su H, Sheng Q, Lang Y, Yu Q, Lv Z, Wang R
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Feb;38(2):e23446

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Oral administration of punicalagin attenuates imiquimod-induced psoriasis by reducing ROS generation and inflammation via MAPK/ERK and NF-κB signaling pathways.

Wang Y, Han D, Huang Y, Dai Y, Wang Y, Liu M, Wang N, Yin T, Du W, He K, Zheng Y
Phytotherapy research : PTR 2024 Feb;38(2):713-726

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[Adipose-derived stem cell-derived exosomes regulate Th2/Treg balance in peripheral blood of AR patients through the mTOR pathway].

Han F, Xu X, Wang Y
Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery 2024 Feb;38(2):140-145

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Serabelisib regulates GSDMD-mediated pyroptosis, apoptosis and migration of hepatoma cells via the PI3K/Akt/E-cadherin signaling pathway.

Li M, Huang Z, Zhou Y
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2024 Feb;33(2):171-181

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Tasquinimod enhances the sensitivity of ovarian cancer cells to cisplatin by regulating the Nur77-Bcl-2 apoptotic pathway.

Lin Y, Liu YQ, Zhu KA, Hu MQ, Li Z, Min XJ
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2024 Feb;33(2):151-161

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Targeted transplantation of engineered mitochondrial compound promotes functional recovery after spinal cord injury by enhancing macrophage phagocytosis.

Xu J, Shi C, Yuan F, Ding Y, Xie Y, Liu Y, Zhu F, Lu H, Duan C, Hu J, Jiang L
Bioactive materials 2024 Feb;32:427-444

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Comprehensive analysis of PSMD family members and validation of PSMD9 as a potential therapeutic target in human glioblastoma.

Li Y, Liu X, Zhao F, Zhao Z, Li X, Wang J, Huang B, Chen A
CNS neuroscience & therapeutics 2024 Feb;30(2):e14366

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CIA-II is associated with lower-grade glioma survival and cell proliferation.

Xiao F, Zhu H, Guo Y, Zhang Z, Sun G, Xiao Y, Hu G, Huang K, Guo H
CNS neuroscience & therapeutics 2024 Feb;30(2):e14340

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Tanshinone IIA, a component of the self-made Xiao-Yin decoction, ameliorates psoriasis by inhibiting IL-17/IL-23 and PTGS2/NF-κB/AP-1 pathways.

Fu L, Li M, Wang P, Chen L, Huang J, Zhang H
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2024 Feb;30(2):e13577

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miR‑186‑5p regulates the inflammatory response of chronic obstructive pulmonary disorder by targeting HIF‑1α.

Fu Y, Zhao J, Chen J, Zheng Y, Mo R, Zhang L, Zhang B, Lin Q, He C, Li S, Lin L, Xie T, Ding Y
Molecular medicine reports 2024 Feb;29(2)

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Identification of differentially expressed genes associated with ferroptosis in Crohn's disease.

Zhang W, Li Z, Li H, Zhang D
Experimental and therapeutic medicine 2024 Feb;27(2):89

---

JAM2 is a prognostic biomarker and inhibits proliferation, metastasis and epithelial-mesenchymal transition in lung adenocarcinoma.

Dong Y, Zhang J, Xie S, Di S, Fan B, Gong T
The journal of gene medicine 2024 Feb;26(2):e3679

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A dihydromyricetin-loaded phellinus igniarius polysaccharide/l-arginine modified chitosan-based hydrogel for promoting wound recovery in diabetic mice via JNK and TGF-β/Smad signaling pathway.

Yang J, Zhang L, Sun S, Zhang S, Ding Q, Chai G, Yu W, Zhao T, Shen L, Gao Y, Liu W, Ding C
International journal of biological macromolecules 2024 Feb;259(Pt 1):129124

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Natural isoflavone glabridin targets PI3Kγ as an adjuvant to increase the sensitivity of MDA-MB-231 to tamoxifen and DU145 to paclitaxel.

Lin H, Ai D, Liu Q, Wang X, Chen Q, Hong Z, Tao Y, Gao J, Wang L
The Journal of steroid biochemistry and molecular biology 2024 Feb;236:106426

---

Repression of YEATS2 induces cellular senescence in hepatocellular carcinoma and inhibits tumor growth.

Wu Q, Zheng Q, Yuan L, Gao D, Hu Y, Jiang X, Zhai Q, Liu M, Xu L, Xu H, Ye J, Zhang F
Cell cycle (Georgetown, Tex.) 2024 Feb;23(4):478-494

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Upregulation of TRIM16 mitigates doxorubicin-induced cardiotoxicity by modulating TAK1 and YAP/Nrf2 pathways in mice.

Guo X, Liu M, Han B, Zheng Y, Zhang K, Bao G, Gao C, Shi H, Sun Q, Zhao Z
Biochemical pharmacology 2024 Feb;220:116009

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PCSK9 regulates myofibroblast transformation through the JAK2/STAT3 pathway to regulate fibrosis after myocardial infarction.

Bao H, Wang X, Zhou H, Zhou W, Liao F, Wei F, Yang S, Luo Z, Li W
Biochemical pharmacology 2024 Feb;220:115996

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Gestational exposure to bisphenol AF causes endocrine disorder of corpus luteum by altering ovarian SIRT-1/Nrf2/NF-kB expressions and macrophage proangiogenic function in mice.

Lu S, Liu M, Liu H, Yang C, Zhu J, Ling Y, Kuang H
Biochemical pharmacology 2024 Feb;220:115954

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Fructus Ligustri Lucidi inhibits ferroptosis in ovariectomy‑induced osteoporosis in rats via the Nrf2/HO‑1 signaling pathway.

Li P, Wang Y, Yan Q, Yang Y, Zhu R, Ma J, Chen Y, Liu H, Zhang Z
Biomedical reports 2024 Feb;20(2):27

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BAP18 acting as a novel peroxisome proliferator-activated receptor α co-regulator contributes to hepatocellular carcinoma progression.

Liu W, Wang S, Lin L, Zou R, Sun H, Zeng K, Wu Y, Li Y, Shigeaki K, Wang X, Wang C, Zhao Y
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166974

---

Palmitic acid and trans-4-hydroxy-3-methoxycinnamate, the active ingredients of Yaobishu formula, reduce inflammation and pain by regulating gut microbiota and metabolic changes after lumbar disc herniation to activate autophagy and the Wnt/β-catenin pathway.

Li S, Chen T, Zhou Y, Li X
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166972

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Farnesoid X receptor overexpression prevents hepatic steatosis through inhibiting AIM2 inflammasome activation in nonalcoholic fatty liver disease.

Xu S, Kong L, Li L, Wang C, Gu J, Luo H, Meng Q
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166930

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Fluorene-9-bisphenol exposure damages the testis in mice through a novel mechanism of ferroptosis.

Feng Q, Liu Y, Zou L, Lei M, Zhu C, Xia W
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Feb;184:114385

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FXR overexpression prevents hepatic steatosis through inhibiting AIM2 inflammasome activation in alcoholic liver disease.

Li L, Kong L, Xu S, Wang C, Gu J, Luo H, Meng Q
Hepatology international 2024 Feb;18(1):188-205

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Human umbilical cord-derived mesenchymal stem cells ameliorate liver fibrosis by improving mitochondrial function via Slc25a47-Sirt3 signaling pathway.

Chen P, Yuan M, Yao L, Xiong Z, Liu P, Wang Z, Jiang Y, Li L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Feb;171:116133

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HDAC6-MYCN-CXCL3 axis mediates allergic inflammation and is necessary for allergic inflammation-promoted cellular interactions.

Kwon Y, Choi Y, Kim M, Jo H, Jeong MS, Jung HS, Jeoung D
Molecular immunology 2024 Feb;166:1-15

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Extra villous trophoblast-derived PDL1 can ameliorate macrophage inflammation and promote immune adaptation associated with preeclampsia.

Cui Y, Wu S, Liu K, Zhao H, Ma B, Gong L, Zhou Q, Li X
Journal of reproductive immunology 2024 Feb;161:104186

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Gestational Diabetes Mellitus Remodels the Fetal Brain Fatty Acid Profile Through Placenta-Brain Lipid Axis in C57BL/6J Mice.

Yu HT, Gong JY, Xu WH, Chen YR, Li YT, Chen YF, Liu GL, Zhang HY, Xie L
The Journal of nutrition 2024 Feb;154(2):590-599

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The involvement of RNA N6-methyladenosine and histone methylation modification in decidualization and endometriosis-associated infertility.

Lin X, Dai Y, Gu W, Zhang Y, Zhuo F, Zhao F, Jin X, Li C, Huang D, Tong X, Zhang S
Clinical and translational medicine 2024 Feb;14(2):e1564

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KLF4 interacts with TXNIP to modulate the pyroptosis in ulcerative colitis via regulating NLRP3 signaling.

Chen Y, Sun L, Liu H, Li J, Guo L, Wang Z
Immunity, inflammation and disease 2024 Feb;12(2):e1199

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Sustainable inflammatory activation following spinal cord injury is driven by thrombin-mediated dynamic expression of astrocytic chemokines.

He B, Niu L, Li S, Li H, Hou Y, Li A, Zhang X, Hao H, Song H, Cai R, Zhou Y, Wang Y, Wang Y
Brain, behavior, and immunity 2024 Feb;116:85-100

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Coenzyme Q10 Protects Against Hyperlipidemia-Induced Osteoporosis by Improving Mitochondrial Function via Modulating miR-130b-3p/PGC-1α Pathway.

Meng M, Wang J, Wang C, Zhao J, Wang H, Zhang Y, Sun H, Liu M
Calcified tissue international 2024 Feb;114(2):182-199

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A Novel Cargo Delivery System-AnCar-Exo(LaIMTS) Ameliorates Arthritis via Specifically Targeting Pro-Inflammatory Macrophages.

Li S, Wu YR, Peng XQ, Chen HG, Zhang TY, Chen H, Yang J, Xie YL, Qi HB, Xiang W, Huang B, Zhou SR, Hu Y, Tan QY, Du XL, Huang JL, Zhang RB, Li XH, Luo FT, Jin M, Su N, Luo XQ, Huang S, Yang P, Yan XJ, Lian JQ, Zhu Y, Xiong Y, Xiao GY, Liu YY, Shen C, Kuang L, Ni ZH, Chen L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(7):e2306143

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METTL16 inhibits papillary thyroid cancer tumorigenicity through m(6)A/YTHDC2/SCD1-regulated lipid metabolism.

Li Q, Wang Y, Meng X, Wang W, Duan F, Chen S, Zhang Y, Sheng Z, Gao Y, Zhou L
Cellular and molecular life sciences : CMLS 2024 Feb 9;81(1):81

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Balancing macrophage polarization via stem cell-derived apoptotic bodies for diabetic wound healing.

Mao J, Qian S, Zhao Q, Zhao B, Lu B, Zhang L, Mao X, Zhang Y, Cui W, Sun X
Med (New York, N.Y.) 2024 Feb 9;5(2):148-168.e8

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MTHFD1 regulates the NADPH redox homeostasis in MYCN-amplified neuroblastoma.

Guan J, Li M, Wang Y, Zhang Y, Que Y, Lu S, Wang J, Zhu J, Huang J, Zhen Z, Sun F, Song M, Zhang Y
Cell death & disease 2024 Feb 9;15(2):124

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Whey Protein Peptide Pro-Glu-Trp Ameliorates Hyperuricemia by Enhancing Intestinal Uric Acid Excretion, Modulating the Gut Microbiota, and Protecting the Intestinal Barrier in Rats.

Qi X, Ma Y, Guan K, Zhao L, Ma Y, Wang R
Journal of agricultural and food chemistry 2024 Feb 7;72(5):2573-2584

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A mouse model to distinguish NLRP6-mediated inflammasome-dependent and -independent functions.

Li R, Zan Y, Wang D, Chen X, Wang A, Tan H, Zhang G, Ding S, Shen C, Wu H, Zhu S
Proceedings of the National Academy of Sciences of the United States of America 2024 Feb 6;121(6):e2321419121

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Identification of a potential signature to predict the risk of postmenopausal osteoporosis.

Geng Y, Shao R, Xu T, Zhang L
Gene 2024 Feb 5;894:147942

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MicroRNA-148a-3p suppresses the glycolysis and Cell proliferation by targeting transmembrane protein 54 in liver cancer.

Yuan X, Wen Y, Shi Q, Zhao Y, Ding J
Biochemical and biophysical research communications 2024 Feb 5;695:149424

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JMJD3 regulate H3K27me3 modification via interacting directly with TET1 to affect spermatogonia self-renewal and proliferation.

Wang J, Liu L, Li Z, Wang H, Ren Y, Wang K, Liu Y, Tao X, Zheng L
BMC genomics 2024 Feb 29;25(1):225

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Warm Acupuncture Reduces Pain and Inflammation in Rats with Lumbar Disc Herniation Induced by Autologous Nucleus Pulposus Transplantation via Regulating p38MAPK/NF-κB Pathway.

Pan F, Zeng F, Chen Y, Zheng Y, Chen Z, Zhu X, Yin MF, Huang Y, Liu Z
Journal of acupuncture and meridian studies 2024 Feb 29;17(1):28-37

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Preliminary exploration of the potential biological functions and prognosis values of RAB4B in pan-cancer combing with experimental validation in BLCA.

Li K, Liang S, Mi H
Translational cancer research 2024 Feb 29;13(2):613-633

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The ARID1A-METTL3-m6A axis ensures effective RNase H1-mediated resolution of R-loops and genome stability.

Zhang J, Chen F, Tang M, Xu W, Tian Y, Liu Z, Shu Y, Yang H, Zhu Q, Lu X, Peng B, Liu X, Xu X, Gullerova M, Zhu WG
Cell reports 2024 Feb 27;43(2):113779

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Human YKT6 forms priming complex with STX17 and SNAP29 to facilitate autophagosome-lysosome fusion.

Zheng D, Tong M, Zhang S, Pan Y, Zhao Y, Zhong Q, Liu X
Cell reports 2024 Feb 27;43(2):113760

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p53 promotes antiviral innate immunity by driving hexosamine metabolism.

Xia W, Jiang P
Cell reports 2024 Feb 27;43(2):113724

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ALOX5 drives the pyroptosis of CD4(+) T cells and tissue inflammation in rheumatoid arthritis.

Cai H, Zhang J, Xu H, Sun W, Wu W, Dong C, Zhou P, Xue C, Nan Y, Ni Y, Wu X, Gu Z, Chen M, Wang Y
Science signaling 2024 Feb 27;17(825):eadh1178

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Nucleoporin Seh1 controls murine neocortical development via transcriptional repression of p21 in neural stem cells.

Dai W, Liu Z, Yan M, Nian X, Hong F, Zhou Z, Wang C, Fu X, Li X, Jiang M, Zhu Y, Huang Q, Lu X, Hou L, Yan N, Wang Q, Hu J, Mo W, Zhang X, Zhang L
Developmental cell 2024 Feb 26;59(4):482-495.e6

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EGR1 mediates MDR1 transcriptional activity regulating gemcitabine resistance in pancreatic cancer.

Yang Z, Chen F, Wei D, Chen F, Jiang H, Qin S
BMC cancer 2024 Feb 26;24(1):268

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S-nitrosothiol homeostasis maintained by ADH5 facilitates STING-dependent host defense against pathogens.

Jia M, Chai L, Wang J, Wang M, Qin D, Song H, Fu Y, Zhao C, Gao C, Jia J, Zhao W
Nature communications 2024 Feb 26;15(1):1750

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NINJ1 mediates inflammatory cell death, PANoptosis, and lethality during infection conditions and heat stress.

Han JH, Karki R, Malireddi RKS, Mall R, Sarkar R, Sharma BR, Klein J, Berns H, Pisharath H, Pruett-Miller SM, Bae SJ, Kanneganti TD
Nature communications 2024 Feb 26;15(1):1739

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DIA proteomics analysis reveals the mechanism of folic acid-induced acute kidney injury and the effects of icariin.

Zhang D, Liu S, Jiang H, Liu S, Kong F
Chemico-biological interactions 2024 Feb 25;390:110878

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Ameliorative Effect of Coenzyme Q10 on Phenotypic Transformation in Human Smooth Muscle Cells with FBN1 Knockdown.

Zhang X, Zhang Z, Wan S, Qi J, Hao Y, An P, Luo Y, Luo J
International journal of molecular sciences 2024 Feb 25;25(5)

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Synergistic suppression of ovarian cancer by combining NRF2 and GPX4 inhibitors: in vitro and in vivo evidence.

Li N, Jiang X, Zhang Q, Huang Y, Wei J, Zhang H, Luo H
Journal of ovarian research 2024 Feb 23;17(1):49

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Protective effects of Pt-N-C single-atom nanozymes against myocardial ischemia-reperfusion injury.

Ye T, Chen C, Wang D, Huang C, Yan Z, Chen Y, Jin X, Wang X, Ding X, Shen C
Nature communications 2024 Feb 23;15(1):1682

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Discovery of D25, a Potent and Selective MNK Inhibitor for Sepsis-Associated Acute Spleen Injury.

Li Q, Ke L, Yu D, Xu H, Zhang Z, Yu R, Jiang T, Guo YW, Su M, Jin X
Journal of medicinal chemistry 2024 Feb 22;67(4):3167-3189

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Development of Potent MALT1 Inhibitors Featuring a Novel "2-Thioxo-2,3-dihydrothiazolo[4,5-d]pyrimidin-7(6H)-one" Scaffold for the Treatment of B Cell Lymphoma.

Liang X, Yu H, Liang R, Feng Z, Saidahmatov A, Sun C, Ren H, Wei X, Zhao J, Yang C, Liu H
Journal of medicinal chemistry 2024 Feb 22;67(4):2884-2906

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The Parkinson's disease related mutant VPS35 (D620N) amplifies the LRRK2 response to endolysosomal stress.

McCarron KR, Elcocks H, Mortiboys H, Urbé S, Clague MJ
The Biochemical journal 2024 Feb 21;481(4):265-278

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Nel-like Molecule Type 1 Combined with Gold Nanoparticles Modulates Macrophage Polarization, Osteoclastogenesis, and Oral Microbiota in Periodontitis.

Liao W, Ni C, Ge R, Li Y, Jiang S, Yang W, Yan F
ACS applied materials & interfaces 2024 Feb 21;16(7):8442-8458

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HMGA1 drives chemoresistance in esophageal squamous cell carcinoma by suppressing ferroptosis.

Yang JY, Lei XY, He KY, Guo JR, Liu MJ, Li JQ, Li QT, Jiang ZH, Zhang L, Wu DH, Li YJ, Sun QH, Jian YP, Xu ZX
Cell death & disease 2024 Feb 21;15(2):158

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[Protective effect of FAK inhibitor PF-562271 against human umbilical vein endothelial cell injury induced by aging platelets].

Bai Y, Gang B, Zhang M, Wan Z, Liu G, Gu W
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2024 Feb 20;44(2):252-259

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The pathogenicity of vancomycin-resistant Enterococcus faecalis to colon cancer cells.

Zhang L, Deng M, Liu J, Zhang J, Wang F, Yu W
BMC infectious diseases 2024 Feb 20;24(1):230

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P21 resists ferroptosis in osteoarthritic chondrocytes by regulating GPX4 protein stability.

Zheng Z, Shang X, Sun K, Hou Y, Zhang X, Xu J, Liu H, Ruan Z, Hou L, Guo Z, Wang G, Xu F, Guo F
Free radical biology & medicine 2024 Feb 20;212:336-348

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SYNJ2BP ameliorates intervertebral disc degeneration by facilitating mitochondria-associated endoplasmic reticulum membrane formation and mitochondrial Zn(2+) homeostasis.

Song Y, Geng W, Zhu D, Liang H, Du Z, Tong B, Wang K, Li S, Gao Y, Feng X, Liao Z, Mei R, Yang C
Free radical biology & medicine 2024 Feb 20;212:220-233

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Ezrin inhibition alleviates oxidative stress and pyroptosis via regulating TRPML1-calcineurin axis mediated enhancement of autophagy in spinal cord injury.

Lou J, Jin M, Zhou C, Fan Y, Ni L, Mao Y, Shen H, Li J, Zhang H, Fu C, Mao X, Chen Y, Zhong J, Zhou K, Wang L, Wu J
Free radical biology & medicine 2024 Feb 20;212:133-148

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A Curcumin-Decorated Nanozyme with ROS Scavenging and Anti-Inflammatory Properties for Neuroprotection.

Gao F, Liang W, Chen Q, Chen B, Liu Y, Liu Z, Xu X, Zhu R, Cheng L
Nanomaterials (Basel, Switzerland) 2024 Feb 20;14(5)

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Transcriptotype-Driven Discovery of Apigenin as a Therapy against Cholestatic Liver Fibrosis: Through Inhibition of PANoptosis and Following Type-I Interferon Responses.

Duan S, Li X, Han J, Yang Y, Luo R, Cai Y, Li X, Zheng Q, Guo J, Liu R
Antioxidants (Basel, Switzerland) 2024 Feb 20;13(3)

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USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1.

Wu Q, Qiu Y, Guo J, Yuan Z, Yang Y, Zhu Q, Zhang Z, Guo J, Wu Y, Zhang J, Huang D, Tu K, Hu X
Biology direct 2024 Feb 2;19(1):13

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The clustering status of detached gastric cancer cells inhibits anoikis-induced ferroptosis to promote metastatic colonization.

Sun J, Li J, Pantopoulos K, Liu Y, He Y, Kang W, Ye X
Cancer cell international 2024 Feb 18;24(1):77

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Tumorigenesis of basal muscle invasive bladder cancer was mediated by PTEN protein degradation resulting from SNHG1 upregulation.

Li T, Huang M, Sun N, Hua X, Chen R, Xie Q, Huang S, Du M, Zhao Y, Lin Q, Xu J, Han X, Zhao Y, Tian Z, Zhang Y, Chen W, Shen X, Huang C
Journal of experimental & clinical cancer research : CR 2024 Feb 17;43(1):50

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Teadenol B as a Component of Microorganism-Fermented Tea Extract Inhibited Breast Cancers by Promoting Autophagy.

Zhao Y, Ding ZG, Yan YJ, Yang R, Qi MM, Pan SK, Xie JL, Sun YH, Xiang J
Molecules (Basel, Switzerland) 2024 Feb 16;29(4)

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KLF2 controls proliferation and apoptosis of human spermatogonial stem cells via targeting GJA1.

Chen W, Cui Y, Li C, He C, Du L, Liu W, He Z
iScience 2024 Feb 16;27(2):109024

---

Investigating HMGB1 as a potential serum biomarker for early diabetic nephropathy monitoring by quantitative proteomics.

Peng R, Zuo S, Li X, Huang Y, Chen S, Zou X, Long H, Chen M, Yang Y, Yuan H, Zhao Q, Guo B, Liu L
iScience 2024 Feb 16;27(2):108834

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Inhibition of RIPK1 alleviating vascular smooth muscle cells osteogenic transdifferentiation via Runx2.

Li Y, Jie W, Qi Y, Mo M, Lian Y, Yin L, Huang H
iScience 2024 Feb 16;27(2):108766

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Total flavonoids of Astragalus protects glomerular filtration barrier in diabetic kidney disease.

Liu PY, Hong KF, Liu YD, Sun ZY, Zhao TT, Li XL, Lao CC, Tan SF, Zhang HY, Zhao YH, Xie Y, Xu YH
Chinese medicine 2024 Feb 16;19(1):27

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ALKBH5 promotes the development of lung adenocarcinoma by regulating the polarization of M2 macrophages through CDCA4.

Tan J, Chen F, Wang J, Li J, Ouyang B, Li X, Li Y, Zhang W, Jiang Y
Gene 2024 Feb 15;895:147975

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Serine synthesis sustains macrophage IL-1β production via NAD(+)-dependent protein acetylation.

Wang C, Chen Q, Chen S, Fan L, Gan Z, Zhao M, Shi L, Bin P, Yang G, Zhou X, Ren W
Molecular cell 2024 Feb 15;84(4):744-759.e6

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Scutellarin targets Wnt5a against zearalenone-induced apoptosis in mouse granulosa cells in vitro and in vivo.

Sun N, Haseeb A, Sun P, Zhang H, Zhong J, Yin W, Fan K, Yang H, Zhang Z, Sun Y, Hu P, Li H
Journal of hazardous materials 2024 Feb 15;464:132917

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Lysine demethylase KDM3A alleviates hyperoxia-induced bronchopulmonary dysplasia in mice by promoting ETS1 expression.

Yang M, Chen Y, Huang X, Shen F, Meng Y
Experimental cell research 2024 Feb 15;435(2):113945

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CHTOP Promotes Microglia-Mediated Inflammation by Regulating Cell Metabolism and Inflammatory Gene Expression.

Zhou X, Lv M, Duan Z, Liu W, Yan F, Liu J, Cui Y
Journal of immunology (Baltimore, Md. : 1950) 2024 Feb 15;212(4):677-688

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The levels of IL1RN is a factor influencing the onset of rheumatoid arthritis in non-alcoholic fatty liver disease.

Gu J, Xu J, Jiao A, Gao Z, Zhang C, Cai N, Xia S, Li J, Wang Z, Chen G, Liu X, Chen Y
International immunopharmacology 2024 Feb 15;128:111528

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L-lysine supplementation attenuates experimental autoimmune hepatitis in a chronic murine model.

Lei Y, Chen Y, Wang S, Lin Z, Han P, Tian D, Wang H, Liu M
Experimental animals 2024 Feb 14;73(1):83-92

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PEDV inhibits HNRNPA3 expression by miR-218-5p to enhance cellular lipid accumulation and promote viral replication.

Shi X, Zhang Q, Yang N, Wang Q, Zhang Y, Xu X
mBio 2024 Feb 14;15(2):e0319723

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Role of TFEB-autophagy lysosomal pathway in palmitic acid induced renal tubular epithelial cell injury.

Cai MY, Jiang XS, Wei YX, Wen RZ, Du XG
Biochemical and biophysical research communications 2024 Feb 12;696:149472

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Exercise enhances placental labyrinth trophoblast development by activation of PGC-1α and FNDC5/irisin†.

Chae SA, Du M, Zhu MJ, Son JS
Biology of reproduction 2024 Feb 10;110(2):355-364

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OXCT1 functions as a succinyltransferase, contributing to hepatocellular carcinoma via succinylating LACTB.

Ma W, Sun Y, Yan R, Zhang P, Shen S, Lu H, Zhou Z, Jiang Z, Ye L, Mao Q, Xiong N, Jia W, Sun L, Gao P, Zhang H
Molecular cell 2024 Feb 1;84(3):538-551.e7

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POH1 induces Smad3 deubiquitination and promotes lung cancer metastasis.

Yuan Y, Li Y, Wu X, Bo J, Zhang L, Zhang J, Hu Y, Chen Y, Zeng Y, Wei X, Zhang H
Cancer letters 2024 Feb 1;582:216526

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TLR9 activation induces immunosuppression and tumorigenesis via PARP1/PD-L1 signaling pathway in oral squamous cell carcinoma.

Ma L, Qin N, Wan W, Song S, Hua S, Jiang C, Li N, Huang L, Gao X
American journal of physiology. Cell physiology 2024 Feb 1;326(2):C362-C381

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Therapeutic application of human type 2 innate lymphoid cells via induction of granzyme B-mediated tumor cell death.

Li Z, Ma R, Tang H, Guo J, Shah Z, Zhang J, Liu N, Cao S, Marcucci G, Artis D, Caligiuri MA, Yu J
Cell 2024 Feb 1;187(3):624-641.e23

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Leptin receptor deficiency impedes metabolic surgery related-weight loss through inhibition of energy expenditure in db/db mice.

Tong D, Xiang J, Liu W, Sun F, Wang L, Mou A, Cao T, Zhou Q, You M, Liao Y, Gao P, Liu D, Lu Z, Zhu Z
Diabetology & metabolic syndrome 2024 Feb 1;16(1):33

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Exosomes from adipose-derived stem cells overexpressing microRNA-671-3p promote fat graft angiogenesis and adipogenic differentiation.

Hao X, Guo Y, Yu X, He L, He Y, Shu M
Tissue & cell 2024 Dec;91:102575

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Astragaloside IV Reduces Lung Epithelial Cell Pyroptosis via TXNIP-NLRP3-GSDMD pathway.

Wu K, Luan G, Hu J, Zhu Z, Kong Z, Yin S
Cell biochemistry and biophysics 2024 Dec;82(4):3695-3702

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Xiao-Ban-Xia Decoction Alleviates Chemotherapy-Induced Nausea and Vomiting by Inhibiting Ferroptosis via Activation of The Nrf2/SLC7A11/GPX4 Pathway.

Liang W, Ren Y, Wang Y, Chen W, Mo Z, Yang C, Nie K
Advanced biology 2024 Dec;8(12):e2400323

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RSL3 sensitizes glioma cells to ionizing radiation by suppressing TGM2-dependent DNA damage repair and epithelial-mesenchymal transition.

Wang X, Shi W, Li M, Xin Y, Jiang X
Redox biology 2024 Dec;78:103438

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Corynoline alleviates hepatic ischemia-reperfusion injury by inhibiting NLRP3 inflammasome activation through enhancing Nrf2/HO-1 signaling.

Ge X, Gu Y, Wang W, Guo W, Wang P, Du P
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Dec;73(12):2069-2085

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Tabersonine enhances cisplatin sensitivity by modulating Aurora kinase A and suppressing epithelial-mesenchymal transition in triple-negative breast cancer.

Chen X, Yan Y, Liu Y, Yi Q, Xu Z
Pharmaceutical biology 2024 Dec;62(1):394-403

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GR/P300 Regulates MKP1 Signaling Pathway and Mediates Depression-like Behavior in Prenatally Stressed Offspring.

Wei B, Shi Y, Yu X, Cai Y, Zhao Y, Song Y, Zhao Z, Huo M, Li L, Gao Q, Yu D, Wang B, Sun M
Molecular neurobiology 2024 Dec;61(12):10613-10628

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The COPII coat protein SEC24D is required for autophagosome closure in mammals.

He T, Ji C, Zhang W, Li X, Liu Y, Wang X, Zhang H, Wang J
FEBS letters 2024 Dec;598(23):2897-2909

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Eclipta prostrata improves alveolar development of bronchopulmonary dysplasia via suppressing the NLRP3 inflammasome in a DLD-dependent manner.

Zheng X, Tan Z, Zhu D, Zhao D, Liu C, Wang S, Wang X, Zhang Y
Pediatric pulmonology 2024 Dec;59(12):3371-3382

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Apelin deficiency exacerbates cardiac injury following infarction by accelerating cardiomyocyte ferroptosis.

Zhao Y, Liang X, Li T, Shao Z, Cao Z, Zeng Y, Yan X, Chen Q, Zhou H, Li W, Cheng G, Jiang Y, Li X, Zhang Y, Hu B
Free radical research 2024 Dec;58(12):854-867

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FOXG1 interaction with SATB2 promotes autophagy to alleviate neuroinflammation and mechanical abnormal pain in rats with lumbar disc herniation.

Wang Z, Gu Y, Wang H, Chen Y, Chen H, Wang X, Yuan W
Annals of medicine 2024 Dec;56(1):2399967

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Bleomycin induces endothelial cell pyroptosis and regulates fibrosis by activating the NLRP3/caspase-1/GSDMD pathway: a possible mechanism contributing to the sclerotherapy of venous malformations.

Chen S, Wang Y, Gao Q, Cui J, Shen W
Journal of molecular histology 2024 Dec;55(6):1239-1250

---

Near-infrared photoimmunotherapy for osteosarcoma targeting epidermal growth factor receptor.

Suzuki M, Kobayashi H, Hanaoka H
Translational oncology 2024 Dec;50:102132

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Dura immunity configures leptomeningeal metastasis immunosuppression for cerebrospinal fluid barrier invasion.

Zhao J, Zeng R, Li X, Lu Y, Wang Z, Peng H, Chen H, Fu M, Zhang Y, Huang Y, Chen W, Wang X, Guan Y, Han W, Huang R, Yao C, Qin Z, Chen L, Chen L, Feng X, Yang H, Pereira PMR, Tong X, Li B, Zhang Q, Chi Y
Nature cancer 2024 Dec;5(12):1940-1961

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Novel lipid metabolism factor HIBCH inhibitor synergizes with doxorubicin to suppress osteosarcoma growth and impacts clinical prognosis in osteosarcoma patients.

Yuan X, Yu B, Ding H, Li H, Wang Q, Lin L, Zhang W, Fang X
Journal of bone oncology 2024 Dec;49:100652

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MiR-454-3p regulates high glucose-induced mesothelial-mesenchymal transition and glycolysis in peritoneal mesothelial cells by targeting STAT3.

Li N, Fu J, Wang Q, Rao Q, Yao L, Shao X, Zhang P
Renal failure 2024 Dec;46(2):2394635

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Nanoparticles transfected with plasmid-encoded lncRNA-OIP5-AS1 inhibit renal ischemia-reperfusion injury in mice via the miR-410-3p/Nrf2 axis.

Zhang R, Zhang X, Zhu X, Li T, Li Y, Zhang P, Chen Y, Li G, Han X
Renal failure 2024 Dec;46(1):2319327

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Geniposide alleviates heart failure with preserved ejection fraction in mice by regulating cardiac oxidative stress via MMP2/SIRT1/GSK3β pathway.

Han YL, Yan TT, Li HX, Chen SS, Zhang ZZ, Wang MY, Chen MJ, Chen YL, Yang XX, Wei LL, Duan YJ, Zhang S
Acta pharmacologica Sinica 2024 Dec;45(12):2567-2578

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Ginsenoside Rg1 mitigates cerebral ischaemia/reperfusion injury in mice by inhibiting autophagy through activation of mTOR signalling.

Xi ZC, Ren HG, Ai L, Wang Y, Liu MF, Qiu YF, Feng JL, Fu W, Bi QQ, Wang F, Xu HX
Acta pharmacologica Sinica 2024 Dec;45(12):2474-2486

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Agomelatine promotes differentiation of oligodendrocyte precursor cells and preserves white matter integrity after cerebral ischemic stroke.

Wang S, Li C, Kang X, Su X, Liu Y, Wang Y, Liu S, Deng X, Huang H, Li T, Lu D, Cai W, Lu Z, Wei L, Lu T
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2024 Dec;44(12):1487-1500

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Glutamine sensing licenses cholesterol synthesis.

Garcia BM, Melchinger P, Medeiros T, Hendrix S, Prabhu K, Corrado M, Kingma J, Gorbatenko A, Deshwal S, Veronese M, Scorrano L, Pearce E, Giavalisco P, Zelcer N, Pernas L
The EMBO journal 2024 Dec;43(23):5837-5856

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Protective effects of electroacupuncture on senile osteoporosis in rats.

Zhou J, Wang J, Qu M, Wang Q, Wang L, Liu S, Liu J, Sun G, Zhong P, Huang X, Liu D, Yin L, He C
Acupuncture in medicine : journal of the British Medical Acupuncture Society 2024 Dec;42(6):334-341

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A Core NRF2 Gene Set Defined Through Comprehensive Transcriptomic Analysis Predicts Selective Drug Resistance and Poor Multicancer Prognosis.

Luo G, Kumar H, Aldridge K, Rieger S, Han E, Jiang E, Chan ER, Soliman A, Mahdi H, Letterio JJ
Antioxidants & redox signaling 2024 Dec;41(16-18):1031-1050

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Complement factor B, not the membrane attack complex component C9, promotes neointima formation after arterial wire injury.

Guo Z, Zhang Y, Peng Z, Rao H, Yang J, Chen Z, Song W, Wan Q, Chen H, Wang M
Atherosclerosis 2024 Dec;399:118586

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NOD2 contributes to Parvimonas micra-induced bone resorption in diabetic rats with experimental periodontitis.

Chen YY, Tan L, Su XL, Chen NX, Liu Q, Feng YZ, Guo Y
Molecular oral microbiology 2024 Dec;39(6):446-460

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RB1 Mutations Induce Smoking-Related Bladder Cancer by Modulating the Cytochrome P450 Pathway.

Mao Z, Gao F, Sun T, Xiao Y, Wu J, Xiao Y, Chu H, Wu D, Du M, Zheng R, Zhang Z
Environmental toxicology 2024 Dec;39(12):5357-5370

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A Homozygous Variant in NAA60 Is Associated with Primary Familial Brain Calcification.

Chen X, Shi Y, Fu F, Wang L, Yu H, Yang D, Wang X, Ying C, Wang H, Lin Z, Wang H, Zhang F, Zheng X, Guo Y, Wang Y, Zeng Y, Zhao M, Chen Y, Li J, Xia H, Chen J, Wang B, Wu S, Xie F, Feng J, Cen Z, Luo W
Movement disorders : official journal of the Movement Disorder Society 2024 Dec;39(12):2190-2198

---

Novel isobavachalcone derivatives induce apoptosis and necroptosis in human non-small cell lung cancer H1975 cells.

Chen J, Zhao L, Xu MF, Huang D, Sun XL, Zhang YX, Li HM, Wu CZ
Journal of enzyme inhibition and medicinal chemistry 2024 Dec;39(1):2292006

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TGN-020 ameliorates motor dysfunction post-spinal cord injury via enhancing astrocyte autophagy and mitigating inflammation by activating AQP4/PPAR-γ/mTOR pathway.

Kong J, Zhang Q, Zheng H, Tang D, Fang L, An S, Li J, Fan Z
Experimental neurology 2024 Dec;382:114975

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Intervention of Tanshinone IIA on the PGK1-PDHK1 Pathway to Reprogram Macrophage Phenotype After Myocardial Infarction.

Gao S, Yang Z, Li D, Wang B, Zheng X, Li C, Fan G
Cardiovascular drugs and therapy 2024 Dec;38(6):1359-1373

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Diphyllin elicits a doubled-pronged attack on the entry of SARS-CoV-2 by inhibiting cathepsin L and furin.

Mao B, Le-Trilling VTK, Tang H, Hu J, Schmitz MS, Barbet K, Xu D, Wei Z, Guo B, Mennerich D, Yao C, Liu J, Li Z, Wan Y, Zhang X, Wang K, Tang N, Yu Z, Trilling M, Lin Y
Virus research 2024 Dec;350:199485

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The E3 ligase ASB3 downregulates antiviral innate immunity by targeting MAVS for ubiquitin-proteasomal degradation.

Cheng M, Lu Y, Wang J, Wang H, Sun Y, Zhao W, Wang J, Shi C, Luo J, Gao M, Yu T, Wang J, Guan J, Wang N, Yang W, Jiang Y, Huang H, Yang G, Cao X, Yang D, Wang C, Zeng Y
Cell death and differentiation 2024 Dec;31(12):1746-1760

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Energy and endoplasmic reticulum stress induction by gold(III) dithiocarbamate and 2-deoxyglucose synergistically trigger cell death in breast cancer.

Orobator ON, Mertens RT, Obisesan OA, Awuah SG
The Journal of biological chemistry 2024 Dec;300(12):107949

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Endoplasmic reticulum stress induces renal fibrosis in high‑fat diet mice via the TGF‑β/SMAD pathway.

Mu Z, Li B, Chen M, Liang C, Gu W, Su J
Molecular medicine reports 2024 Dec;30(6)

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A Novel Compound Ligusticum Cycloprolactam Alleviates Neuroinflammation After Ischemic Stroke via the FPR1/NLRP3 Signaling Axis.

Gao J, Su G, Liu J, Song J, Chen W, Chai M, Xie X, Wang M, Liu J, Zhang Z
CNS neuroscience & therapeutics 2024 Dec;30(12):e70158

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Spatial multi-omics characterizes GPR35-relevant lipid metabolism signatures across liver zonation in MASLD.

Otkur W, Zhang Y, Li Y, Bao W, Feng T, Wu B, Ma Y, Shi J, Wang L, Pei S, Wang W, Wang J, Zhao Y, Liu Y, Li X, Xia T, Wang F, Chen D, Liang X, Piao HL
Life metabolism 2024 Dec;3(6):loae021

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Thioredoxin reductase inhibition and glutathione depletion mediated by glaucocalyxin A promote intracellular disulfide stress in gastric cancer cells.

Wang L, Sun S, Liu H, Zhang Q, Meng Y, Sun F, Zhang J, Liu H, Xu W, Ye Z, Zhang J, Sun B, Xu J
The FEBS journal 2024 Dec;291(23):5276-5289

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Sirtuin 7 ameliorates cuproptosis, myocardial remodeling and heart dysfunction in hypertension through the modulation of YAP/ATP7A signaling.

Chen YF, Qi RQ, Song JW, Wang SY, Dong ZJ, Chen YH, Liu Y, Zhou XY, Li J, Liu XY, Zhong JC
Apoptosis : an international journal on programmed cell death 2024 Dec;29(11-12):2161-2182

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WTAP-mediated m(6)A modification of TRIM22 promotes diabetic nephropathy by inducing mitochondrial dysfunction via ubiquitination of OPA1.

Zhang Z, Zhou F, Lu M, Zhang D, Zhang X, Xu S, He Y
Redox report : communications in free radical research 2024 Dec;29(1):2404794

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Ivacaftor attenuates gentamicin-induced ototoxicity through the CFTR-Nrf2-HO1/NQO1 pathway.

Hu R, Wu F, Zheng YQ
Redox report : communications in free radical research 2024 Dec;29(1):2332038

---

Enhanced therapeutic potential of a self-healing hyaluronic acid hydrogel for early intervention in osteoarthritis.

Wu D, Yang S, Gong Z, Zhu X, Hong J, Wang H, Xu W, Lai J, Wang X, Lu J, Fang X, Jiang G, Zhu J
Materials today. Bio 2024 Dec;29:101353

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Taxifolin-loaded cellulose/l-arginine-chitosan hydrogel promoting bone defect repair through osteogenesis and angiogenesis.

Yang J, Han Y, Zhang L, Ding Q, Sun S, Zhang S, Wang Y, Wang N, Wei H, Yu T, Liu W, Ding C
International journal of biological macromolecules 2024 Dec;283(Pt 3):137843

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Schlafen5, regulated by the AP-1 family transcription factor c-Fos, affects diabetic wound healing through modulating PI3K/Akt/NRF2 axis.

Fan YP, Lou JS, Wei ZQ, Zhou CH, Shen HH, Wei ZY, Mao XJ, Hong L, Qian J, Jin MR, Wu JS
International journal of biological macromolecules 2024 Dec;283(Pt 3):137805

---

Vimentin as a universal receptor for pseudorabies virus infection in pig and human cells.

Li X, Zheng J, Lv X, Han Y, Jiang B, Zhang X, Zhang G, Ren L
International journal of biological macromolecules 2024 Dec;283(Pt 2):137638

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Role of Rab35 in modulating lipid metabolism and viral entry during pseudorabies virus infection.

Cai MP, Qu CL, Du MH, Wang SY, Yang GY, Chu BB, Ming SL
International journal of biological macromolecules 2024 Dec;282(Pt 6):137492

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Circular RNA circWBSCR22 facilitates colorectal cancer metastasis by enhancing CHD4's protein stability.

Luo J, Xu S, Wang J, He L, Li Z
International journal of biological macromolecules 2024 Dec;282(Pt 4):137135

---

Mulberry leaf polysaccharides ameliorate glucose and lipid metabolism disorders via the gut microbiota-bile acids metabolic pathway.

Dai H, Shan Z, Shi L, Duan Y, An Y, He C, Lyu Y, Zhao Y, Wang M, Du Y, Xie J, Yang Y, Zhao B
International journal of biological macromolecules 2024 Dec;282(Pt 2):136876

---

Identification and validation of autophagy‑related genes in hypertrophic cardiomyopathy.

Qiu RB, Zhao ST, Li ZW, Zeng RY, Qiu ZC, Peng HZ, Xu ZQ, Zhou LF, Lai SQ, Wan L
Experimental and therapeutic medicine 2024 Dec;28(6):440

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Pharmacological Network Analysis of the Functions and Mechanism of Quercetin From Jisuikang (JSK) in Spinal Cord Injury (SCI).

Dong L, He H, Chen Z, Wang X, Li Y, Lü G, Wang B, Kuang L
Journal of cellular and molecular medicine 2024 Dec;28(24):e70269

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Ursolic acid attenuates pseudo-allergic reactions via reducing MRGPRX2-mediated mast cell degranulation.

Yan PP, Huang TT, Liu SY, Attiogbe MKI, Liu YN, Shen FQ, Mi YN, Cao YX
Immunology letters 2024 Dec;270:106934

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YAP1 Overexpression Enhances the Aerobic Glycolysis Process via Suppression of EGLN2 in Pancreatic Ductal Adenocarcinoma.

Hu P, Dou R, Qi Z, Liu G, Su Y
The journal of gene medicine 2024 Dec;26(12):e70006

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Targeting the transcription factor YY1 is synthetic lethal with loss of the histone demethylase KDM5C.

Zheng Q, Li P, Qiang Y, Fan J, Xing Y, Zhang Y, Yang F, Li F, Xiong J
EMBO reports 2024 Dec;25(12):5408-5428

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Hyperglycemia-depleted glutamine contributes to the pathogenesis of diabetic corneal endothelial dysfunction.

Yu M, Chen H, Chen C, Zhao C, Zhou Q, Xie L, Wang T
Experimental eye research 2024 Dec;249:110124

---

PX-478 induces apoptosis in acute myeloid leukemia under hypoxia by inhibiting the PI3K/AKT/mTOR pathway through downregulation of GBE1.

Liu W, Dou C, Zhang C, Chen P, Zhang S, Wang R, Han Q, Zhao H, Li D
Biochemical pharmacology 2024 Dec;230(Pt 3):116620

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ITFG2 as a NEDD4-2 inhibitor: Preserving calcium homeostasis to prevent myocardial ischemic injury.

Liu F, Lv LF, Bi FF, Pan QM, Jing ZH, Cui C, Cao M, Yu T, Li J, He YJ, Xiao HW, Tian H, Wu Y, Shan HL, Zhou YH
Biochemical pharmacology 2024 Dec;230(Pt 2):116597

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Sex differences in the metabolic activation of and platelet response to vicagrel in mice: Androgen as a key player.

Jiang LP, Fu M, Yin N, Jia YM, Duan FY, Feng L, Yang L, Han HR, Wang J, Zhu T, Ji JZ, Tai T, Li XM, Zheng ZD, Ding PJ, Sun YL, Mi QY, Xie HG
Biochemical pharmacology 2024 Dec;230(Pt 1):116564

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Integration of single-nucleus and exosome RNA sequencing dissected inter-cellular communication and biomarkers in pancreatic ductal adenocarcinoma.

Tang R, Zhang Z, Xu J, Wang W, Meng Q, Liu Y, Du Q, Liang C, Hua J, Zhang B, Yu X, Shi S
Computational and structural biotechnology journal 2024 Dec;23:1689-1704

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Downregulation of ABLIM3 confers to the metastasis of neuroblastoma via regulating the cell adhesion molecules pathway.

Gong B, Qu T, Zhang J, Jia Y, Song Z, Chen C, Yang J, Wang C, Liu Y, Jin Y, Cao W, Zhao Q
Computational and structural biotechnology journal 2024 Dec;23:1547-1561

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New TIPARP inhibitor rescues mitochondrial function and brain injury in ischemic stroke.

Cai Y, Gu H, Li L, Liu X, Bai Y, Shen L, Han B, Xu Y, Yao H
Pharmacological research 2024 Dec;210:107508

---

Ectopic expression of NKG7 enhances CAR-T function and improves the therapeutic efficacy in liquid and solid tumors.

Chen Y, Wang M, Huang S, Han L, Cai Y, Xu X, Sun S, Chen Z, Chen J, Yu J, Du H, Li H, Zheng J, Ma B, Wang G
Pharmacological research 2024 Dec;210:107506

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ARID1A is a coactivator of STAT5 that contributes to CD8(+) T cell dysfunction and anti-PD-1 resistance in gastric cancer.

Ma F, Ren M, Li Z, Tang Y, Sun X, Wang Y, Cao N, Zhu X, Xu Y, Wang R, Shen Y, Zhao R, Li Z, Ashrafizadeh M, Sethi G, Wang F, Zhao A
Pharmacological research 2024 Dec;210:107499

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FBXL19 Targeted STK11 Degradation Enhances Cigarette Smoke-Induced Airway Epithelial Cell Cytotoxicity.

Li X, Lakshmi SP, Uemasu K, Lane Z, Reddy RT, Chandra D, Zou C, Jiang Y, Nyunoya T
COPD 2024 Dec;21(1):2342797

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Honeycomb Bionic Graphene Oxide Quantum Dot/Layered Double Hydroxide Composite Nanocoating Promotes Osteoporotic Bone Regeneration via Activating Mitophagy.

Li D, Dai D, Wang J, Zhang C
Small (Weinheim an der Bergstrasse, Germany) 2024 Dec;20(50):e2403907

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Protective effect of lycorine hydrochloride against diabetic nephropathy in high-fat diet and streptozotocin-induced diabetic mice.

Fang KL, Qi XY, Han QT, Chen LZ, Wang XN, Xu ZP, Shang LQ, Shen T
Pharmaceutical science advances 2024 Dec;2:100035

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Intestinal barrier, immunity and gut microbiota-based protective effects of Lactococcus lactis HF08 and its postbiotic derivative on aging and aging colitis mice.

Liu X, Ma Y, Guan K, Liu R, Mao K, Xu X, Li Q, Wang R
Food research international (Ottawa, Ont.) 2024 Dec;197(Pt 1):115164

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Ameliorative effects of Trichosanthes kirilowii Maxim. seed oil on hyperlipidemia rats associated with the regulation of gut microbiology and metabolomics.

Chen W, Zhou Z, Qi R, Zhou J, Liang H, Huang P, Zou Z, Dong L, Li H, Du B, Li P
Food research international (Ottawa, Ont.) 2024 Dec;197(Pt 1):115141

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Calpain-1 Up-Regulation Promotes Bleomycin-Induced Pulmonary Fibrosis by Activating Ferroptosis.

Wei S, Liu Y, Ran C, Li Y, Tang B, Lu M, Wang H
The American journal of pathology 2024 Dec;194(12):2272-2289

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Methyltransferase-Like 3-Driven N6-Methyladenosine Modification of Recombination Signal Binding Protein for Immunoglobulin Kappa J Region Promotes Vascular Remodeling in Pulmonary Hypertension.

Du Q, Zhang C, Qu T, Zhou X, Liu Y, Chen Z, Shen Z, Chen P, Zhang R
The American journal of pathology 2024 Dec;194(12):2252-2271

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Simultaneous targeting of TGF-β1/PD-L1 via a hydrogel-nanoparticle system to remodel the ECM and immune microenvironment for limiting adhesion formation.

Yang QQ, Jin J, Sun J, Zhang L, Tang JB, Zhou YL
Acta biomaterialia 2024 Dec;190:447-462

---

MK-801-exposure induces increased translation efficiency and mRNA hyperacetylation of Grin2a in the mouse prefrontal cortex.

Xue L, Zhao J, Liu X, Zhao T, Zhang Y, Ye H
Epigenetics 2024 Dec;19(1):2417158

---

Study on chromatin regulation patterns of expression vectors in the PhiC31 integration site.

Liu X, Chen Q, Yin X, Wang X, Ran J, Yu W, Wang B
Epigenetics 2024 Dec;19(1):2337085

---

m6A reader YTHDC2 mediates NCOA4 mRNA stability affecting ferritinophagy to alleviate secondary injury after intracerebral haemorrhage.

Li F, Wang F, Wang L, Wang J, Wei S, Meng J, Li Y, Feng L, Jiang P
Epigenetics 2024 Dec;19(1):2326868

---

TRIM40 interacts with ROCK1 directly and inhibits colorectal cancer cell proliferation through the c-Myc/p21 axis.

Hu F, Zhao L, Wang J, Li X, Xue Z, Ma Y, Zheng M, Chen C, Tong M, Guo X, Li H, Jin H, Xie Q, Zhang X, Huang C, Huang H
Biochimica et biophysica acta. Molecular cell research 2024 Dec;1871(8):119855

---

UBAP2 contributes to radioresistance by enhancing homologous recombination through SLC27A5 ubiquitination in hepatocellular carcinoma.

Liu Z, Yuan J, Zeng Q, Wu Z, Han J
Biochimica et biophysica acta. Molecular basis of disease 2024 Dec;1870(8):167481

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HBx integration in diffuse large B-cell lymphoma inhibits Caspase-3-PARP related apoptosis.

Wang Y, Guan X, Lv F, Rong Y, Meng X, Tong Y, Ma X, Zheng H, Chen C, Xie S, Zhang H, Dong F, Guo L, Lu R
Tumour virus research 2024 Dec;18:200290

---

ATF3 deficiency promotes alveolar macrophage pyroptosis in sepsis-induced acute lung injury.

Li D, Ma H, Dong X, Fang Z, Zhang C, Song Q, Wang J, Wan X
Molecular immunology 2024 Dec;176:84-95

---

Deciphering the therapeutic potential of Myeloid-Specific JAK2 inhibition in acute respiratory distress syndrome.

Gao S, Li W, Huang Z, Deiuliis JA, Braunstein Z, Liu X, Li X, Kosari M, Chen J, Min X, Yang H, Gong Q, Liu Z, Wei Y, Zhang Z, Dong L, Zhong J
Mucosal immunology 2024 Dec;17(6):1273-1284

---

LncRNA MYOSLID contributes to PH via targeting BMPR2 signaling in pulmonary artery smooth muscle cell.

Chen Y, Li Y, Leng B, Cao C, Wu G, Ye S, Deng L
Vascular pharmacology 2024 Dec;157:107439

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The predominant role of IgM in grouper (Epinephelus coioides) mucosal defense against ectoparasitic protozoan infection.

Mo Z, Lin H, Lai X, Dan P, Wu H, Luo X, Dan X, Li Y
Fish & shellfish immunology 2024 Dec;155:110023

---

Molecular mechanism of infectious spleen and kidney necrosis virus in manipulating the hypoxia-inducible factor pathway to augment virus replication.

He J, Yu Y, Liu W, Li Z, Qi Z, Weng S, Guo C, He J
Virulence 2024 Dec;15(1):2349027

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Discovery of a potent PROTAC degrader for RNA demethylase FTO as antileukemic therapy.

Liu L, Qiu Y, Suo Y, Tong S, Wang Y, Zhang X, Chen L, Huang Y, Zhou H, Zhou H, Dong Z, Yang CG
Acta pharmaceutica Sinica. B 2024 Dec;14(12):5382-5392

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Intestinal epithelial cell NCoR deficiency ameliorates obesity and metabolic syndrome.

Hou S, Yu H, Liu C, Johnson AMF, Liu X, Jiang Q, Zhao Q, Kong L, Wan Y, Xing X, Chen Y, Chen J, Wu Q, Zhang P, Jiang C, Cui B, Li P
Acta pharmaceutica Sinica. B 2024 Dec;14(12):5267-5285

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Taohe Chengqi decoction improves diabetic cognitive dysfunction by alleviating neural stem cell senescence through HIF1α-driven metabolic signaling.

Qin T, He Z, Hassan HM, Wang Q, Shi L, Yu Y, Zhou Y, Zhang W, Yuan Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156219

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Diammonium glycyrrhizinate alleviates iron overload-induced liver injury in mice via regulating the gut-liver axis.

Liu Y, Li X, Guo Z, Li G, He L, Liu H, Cai S, Huo T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156216

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Avicularin inhibits ferroptosis and improves cognitive impairments in Alzheimer's disease by modulating the NOX4/Nrf2 axis.

Li Z, Lu Y, Zhen Y, Jin W, Ma X, Yuan Z, Liu B, Zhou XL, Zhang L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156209

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Suyin Detoxification Granule alleviates trimethylamine N-oxide-induced tubular ferroptosis and renal fibrosis to prevent chronic kidney disease progression.

Ge H, Wei Y, Zhang W, Yong C, Chen Y, Zhou E
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156195

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Kaixinsan regulates neuronal mitochondrial homeostasis to improve the cognitive function of Alzheimer's disease by activating CaMKKβ-AMPK-PGC-1α signaling axis.

Ren J, Xiang B, Song L, René DJ, Luo Y, Wen G, Gu H, Yang Z, Zhang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156170

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Astragaloside IV and cycloastragenol promote liver regeneration through regulation of hepatic oxidative homeostasis and glucose/lipid metabolism.

Li Y, Yang X, Li X, Wang S, Chen P, Ma T, Zhang B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156165

---

Fangchinoline suppresses hepatocellular carcinoma by regulating ROS accumulation via the TRIM7/Nrf2 signaling pathway.

Liu Y, Wang Y, Wang J, Wang X, Chen L, Han T, Lian H, Gan M, Wang J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156143

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Shikonin induces ferroptosis in osteosarcomas through the mitochondrial ROS-regulated HIF-1α/HO-1 axis.

Lu C, Zhang Z, Fan Y, Wang X, Qian J, Bian Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156139

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Integrated gut microbiota and serum pharmacochemistry reveal the mechanisms of wine steaming in alleviating rhubarb diarrhea.

Bai YY, Tian R, Qian Y, Zhao CB, Yan YG, Zhang L, Yue SJ, Zhang Q, Wang YW, Tang YP
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156105

---

Jiang Tang San Hao Formula exerts its anti-diabetic effect by affecting the gut-microbiota-brain axis.

Bai Y, Zhao Y, Jin J, Ye Z, Fan H, Zhao D, Gao S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156100

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A combined treatment with Ursolic acid and Solasodine inhibits colorectal cancer progression through the AKT1/ERK1/2-GSK-3β-β-catenin axis.

Yang Y, Liu P, Jin Y, Zhu H, Wang M, Jiang X, Gao H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156068

---

Catalpol ameliorates liver fibrosis via inhibiting aerobic glycolysis by EphA2/FAK/Src signaling pathway.

Zhang Q, Ran T, Li S, Han L, Chen S, Lin G, Wu H, Wu H, Feng S, Chen J, Zhang Q, Zhao X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156047

---

Loss of MMP9 disturbs cranial suture fusion via suppressing cell proliferation, chondrogenesis and osteogenesis in mice.

Liu M, Zhang H, Li Y, Huang D, Zuo H, Yang J, Chen Z
Matrix biology : journal of the International Society for Matrix Biology 2024 Dec;134:93-106

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miR-361-3p overexpression promotes apoptosis and inflammation by regulating the USP49/IκBα/NF-κB pathway to aggravate sepsis-induced myocardial injury.

Geng H, Qi L, You L, Feng W, Yang X, Lei M
Toxicology research 2024 Dec;13(6):tfae190

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Self-Produced O(2) CNs-Based Nanocarriers of DNA Hydrophobization Strategy Triggers Photodynamic and Mitochondrial-Derived Ferroptosis for Hepatocellular Carcinoma Combined Treatment.

Liu MX, Liu YC, Cai YT, Gu YY, Zhu YQ, Zhang N, Zhu WZ, Liu YH, Yu L, Zhang QT, Zhang XL
Advanced healthcare materials 2024 Dec;13(31):e2402110

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Inhibition of RAN attenuates influenza a virus replication and nucleoprotein nuclear export.

Cao L, She Z, Zhao Y, Cheng C, Li Y, Xu T, Mao H, Zhang Y, Hui X, Lin X, Wang T, Sun X, Huang K, Zhao L, Jin M
Emerging microbes & infections 2024 Dec;13(1):2387910

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Novel transcription and replication-competent virus-like particles system modelling the Nipah virus life cycle.

Wang Y, Fan L, Ye P, Wang Z, Liang C, Liu Q, Yang X, Long Z, Shi W, Zhou Y, Lin J, Yan H, Huang H, Liu L, Qian J
Emerging microbes & infections 2024 Dec;13(1):2368217

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Txnip promotes autophagic apoptosis in diabetic cardiomyopathy by upregulating FoxO1 and its acetylation.

Zhang Y, Li B, Fu Y, Cai H, Zheng Y
Cellular signalling 2024 Dec;124:111469

---

Disrupting the protein-protein interaction network of Hsp72 inhibits adipogenic differentiation and lipid synthesis in adipocytes.

Hu YT, Lin YW, Guo SY, Jiang Z, Xu SM, Su Z, Zhang JM, Rao Y, Chen SB, Huang ZS
Cellular signalling 2024 Dec;124:111431

---

Mycobacterium manipulate glutaminase 1 mediated glutaminolysis to regulate macrophage autophagy for bacteria intracellular survival.

Yu J, Yan N, Gong Z, Ma Q, Liu J, Wu X, Deng G
Cellular signalling 2024 Dec;124:111422

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Pharmacological inhibition of SREBP1 suppresses pancreatic cancer growth via inducing GPX4-mediated ferroptosis.

Cao R, Feng Z, Mo J, Wu J, Li J, Li W, Wang Z, Ma Q, Wu Z, Zhou C
Cellular signalling 2024 Dec;124:111381

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N-butylphthalide (NBP) ameliorated ischemia/reperfusion-induced skeletal muscle injury in male mice via activating Sirt1/Nrf2 signaling pathway.

Lu P, Li WP, Zhou BJ, Tian WZ, Lu X, Gao W
Physiological reports 2024 Dec;12(23):e70149

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SNRPB2 promotes triple-negative breast cancer progression by controlling alternative splicing of MDM4 pre-mRNA.

Yu S, Si Y, Yu J, Jiang C, Cheng F, Xu M, Fan Z, Liu F, Liu C, Wang Y, Wang N, Liu C, Bi C, Sun H
Cancer science 2024 Dec;115(12):3915-3927

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A substitution at the cytoplasmic tail of the spike protein enhances SARS-CoV-2 infectivity and immunogenicity.

Li Y, Zhang X, Tai W, Zhuang X, Shi H, Liao S, Yu X, Mei R, Chen X, Huang Y, Liu Y, Liu J, Liu Y, Zhu Y, Wang P, Tian M, Yu G, Li L, Cheng G
EBioMedicine 2024 Dec;110:105437

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Discovery of Balasubramide Derivative with Tissue-Specific Anti-Inflammatory Activity Against Acute Lung Injury by Targeting VDAC1.

Song JQ, Shen LJ, Wang HJ, Liu QB, Ye LB, Liu K, Shi L, Cai B, Lin HS, Pang T
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(48):e2410550

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Ultra-Long-Term Anti-Inflammatory Polyphenol Capsule to Remodel the Microenvironment for Accelerating Osteoarthritis Healing by Single Dosage.

Wei S, Shou Z, Yang D, Sun L, Guo Y, Wang Y, Zan X, Li L, Zhang C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(48):e2407425

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Hyperglycemia-Enhanced Neutrophil Extracellular Traps Drive Mucosal Immunopathology at the Oral Barrier.

Wang Q, Lin W, Lei K, Wang H, Zhang X, Jiang S, Zhang D, Wang W, Cao S, Li Y, Yu B, Wang Y, Yin Q, Yuan Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(47):e2407346

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Hepatocyte-Targeted Lipid Nanoparticle Delivery of HERC2 Plasmid Controls Drug-Induced Hepatotoxicity by Limiting β-Catenin-Regulated CYP2E1 Expression.

Liu Y, Xu Q, Liu Y, Cao S, Luo J, Zheng Z, Zhou J, Lu X, Zhang L, Tan Y, Chen Q, Zuo D
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(46):e2401633

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Gq/G11 oncogenic mutations promote PD-L1 expression and suppress tumor immunity.

Dong J, Xu Y, Yu D, Zhang X, Wang A, Lv L, Li Z
European journal of cell biology 2024 Dec;103(4):151467

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IGFBP7 promotes the proliferation and differentiation of primary myoblasts and intramuscular preadipocytes in chicken.

Geng W, Guo Y, Chen B, Cheng X, Li S, Challioui MK, Tian W, Li H, Zhang Y, Li Z, Jiang R, Tian Y, Kang X, Liu X
Poultry science 2024 Dec;103(12):104258

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Hypoxia drives estrogen receptor β-mediated cell growth via transcription activation in non-small cell lung cancer.

Su Q, Chen K, Ren J, Zhang Y, Han X, Leong SW, Wang J, Wu Q, Tu K, Sarwar A, Zhang Y
Journal of molecular medicine (Berlin, Germany) 2024 Dec;102(12):1471-1484

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Elevated levels of intracellular RNA lariats suppress the antiviral response.

Duan C, Buerer L, Bowers C, Taggart AJ, O'Brien MH, Gunasekera S, Lin CL, Wang J, Staley JP, Fredericks AM, Monaghan SF, Welch A, Clark NE, Gao D, Marr N, Zhang SY, Casanova JL, Fairbrother WG
bioRxiv : the preprint server for biology 2024 Dec 8;

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Myricanol represses renal fibrosis by activating TFAM and ZNRF1 to inhibit tubular epithelial cells ferroptosis.

Zheng M, Jiang Q, You J, Gao B, Cui W, Yao W, Su F, Sun X, La L
European journal of pharmacology 2024 Dec 5;984:176999

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Fucoidan from Laminaria japonica protects renal tubular epithelial cells from uric acid induced NLRP3-mediated pyroptosis through inhibition of NF-κB pathway.

Tan X, Zhang Y, Luo P, Lin Z, Li F, Liu H
Journal of ethnopharmacology 2024 Dec 5;335:118614

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Indoleamine-2,3-dioxygenase (IDO) Mediates the Suppression of T Cells by IFN-γ Primed Mesenchymal Stromal Cells in the Treatment of Psoriasis-Like Inflammation.

Zhu W, Qi C, Shi C, Yang H, Shi F, Ding Y
Frontiers in bioscience (Landmark edition) 2024 Dec 5;29(12):411

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The miR-6240 target gene Igf2bp3 promotes myoblast fusion by enhancing myomaker mRNA stability.

Huang Y, Wang W, Fan X, Liu X, Liu W, Wang Z, Li Y, Yang Y, Tang Z
Cellular & molecular biology letters 2024 Dec 5;29(1):152

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Discovery of novel substituted pyridine carboxamide derivatives as potent allosteric SHP2 inhibitors.

Lv X, Li P, Chen Z, Huang S, Zhang S, Ji B, Liu J, Du T, Zhang T, Chen X, Qiang L, He Y, Lai Y
European journal of medicinal chemistry 2024 Dec 5;279:116830

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Discovery of potent LRRK2 inhibitors by ensemble virtual screening strategy and bioactivity evaluation.

Gong X, Li S, Huang J, Tan S, Zhang Q, Tian Y, Li Q, Wang L, Tong HHY, Yao X, Chen C, Lee SM, Liu H
European journal of medicinal chemistry 2024 Dec 5;279:116812

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Porphyromonas gingivalis inducing autophagy-related biological dysfunction in alveolar epithelial cells: an in vitro study.

Zhao Q, Wang X, Liu W, Tian H, Yang H, Wang Z, Liu Z
BMC oral health 2024 Dec 5;24(1):1478

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The epigenetic-modified downregulation of LOXL1 protein mediates EMT in bladder epithelial cells exposed to benzo[a]pyrene and its metabolite BPDE.

Zou R, Lu J, Bai X, Yang Y, Zhang S, Wu S, Tang Z, Li K, Hua X
International immunopharmacology 2024 Dec 5;142(Pt B):113232

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BMAL1 alleviates sepsis-induced AKI by inhibiting ferroptosis.

Yang S, Ye Z, Chen W, Wang P, Zhao S, Zhou X, Li W, Cheng F
International immunopharmacology 2024 Dec 5;142(Pt B):113159

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RNF39 facilitates antiviral immune responses by promoting K63-linked ubiquitination of STING.

Wang W, Li Q, Jia M, Wang C, Liang W, Liu Y, Kong H, Qin Y, Zhao C, Zhao W, Song H
International immunopharmacology 2024 Dec 5;142(Pt A):113091

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Nicotine aggravates high-fat diet-induced non-alcoholic fatty liver disease in mice via inhibition of CISD3.

Wei Y, Pan T, Zhao Y, Chen Z, Wu L, Fang S, Wang X, Wang X, Chen D, Chen Y
International immunopharmacology 2024 Dec 5;142(Pt A):113067

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miR-548az-5p induces amniotic epithelial cell senescence by regulating KATNAL1 expression in labor.

Jing D, Liu Q, Zhang H, Li Y, Jiang X, Cai Y, Wang X, Li L
Scientific reports 2024 Dec 5;14(1):30380

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Molecular Insights into the Regulation of GNPTAB by TMEM251.

Yang X, Doray B, Venkatarangan V, Jennings BC, Henn D, Liang J, Zhao H, Zhang W, Zhang B, Yu L, Chen L, Kornfeld S, Li M
bioRxiv : the preprint server for biology 2024 Dec 5;

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Subcellular Proteomic Mapping of Lysine Lactylation.

Bao Q, Wan N, He Z, Cao J, Yuan W, Hao H, Ye H
Journal of the American Society for Mass Spectrometry 2024 Dec 4;35(12):3221-3232

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Role of intermittent hypoxic training combined with methazolamide in the prevention of high-altitude cerebral edema in rats.

Peng W, Ma H, Zhao R, Xu S, Lv M, Jing B, Hu Z
Scientific reports 2024 Dec 4;14(1):30252

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The X-linked intellectual disability gene CUL4B is critical for memory and synaptic function.

Jiang W, Zhang J, Wang M, Zou Y, Liu Q, Song Y, Sun G, Gong Y, Zhang F, Jiang B
Acta neuropathologica communications 2024 Dec 4;12(1):188

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CK1δ/ε-mediated TDP-43 phosphorylation contributes to early motor neuron disease toxicity in amyotrophic lateral sclerosis.

Ko VI, Ong K, Kwon DY, Li X, Pietrasiewicz A, Harvey JS, Lulla M, Bhat G, Cleveland DW, Ravits JM
Acta neuropathologica communications 2024 Dec 4;12(1):187

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Liu-Shen-Wan inhibits PI3K/Akt and TRPV1 signaling alleviating bone cancer pain in rats.

Zhang H, Jiang J, Chen X, Zhu F, Fu F, Chen A, Fu L, Mao D
Cancer biology & therapy 2024 Dec 31;25(1):2432098

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The anticancer mechanisms of Toxoplasma gondii rhoptry protein 16 on lung adenocarcinoma cells.

Li G, Li Q, Tong Y, Zeng J, Dang T, Yang N, Zhou Y, Ma L, Ge Q, Zhao Z
Cancer biology & therapy 2024 Dec 31;25(1):2392902

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BRG1 promotes liver cancer cell proliferation and metastasis by enhancing mitochondrial function and ATP5A1 synthesis through TOMM40.

Hui Y, Leng J, Jin D, Wang G, Liu K, Bu Y, Wang Q
Cancer biology & therapy 2024 Dec 31;25(1):2375440

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miR-10b-5p promotes tumor growth by regulating cell metabolism in liver cancer via targeting SLC38A2.

Xia M, Chen J, Hu Y, Qu B, Bu Q, Shen H
Cancer biology & therapy 2024 Dec 31;25(1):2315651

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CSE1L in enhancing the effect of defactinib on gastric cancer cells via the inhibition of FAK phosphorylation.

He X, Wang Y, Zhang Y, Sahu A, Almhanna K, Liu Y
Translational cancer research 2024 Dec 31;13(12):6905-6918

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Deubiquitination of aryl hydrocarbon receptor by USP21 negatively regulates T helper 17 cell differentiation.

Wang L, Cheng H, Wang X, Zhu F, Tian N, Xu Z, Yin H, Liang M, Yang X, Liu X, Shan H, Fu R, Cao B, Li D, Xiao L, Lu L, Dai SM, Wang Q, Lv L, Zou H, Li B
Journal of leukocyte biology 2024 Dec 31;117(1)

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Clostridium difficile-derived membrane vesicles promote fetal growth restriction via inhibiting trophoblast motility through PPARγ/RXRα/ANGPTL4 axis.

Zha Z, Jia C, Zhou R, Yin Q, Hu Y, Huang Z, Peng L, Zhang Y, Qiu X, Chen Y, Zhong Y, Wang Y, Pang M, Lu S, Sheng C, Huang L
NPJ biofilms and microbiomes 2024 Dec 31;10(1):158

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DNAJB4/HLJ1 deficiency sensitizes diethylnitrosamine-induced hepatocarcinogenesis with peritumoral STAT3 activation.

Luo WJ, Hsu WL, Lu CY, Chien MH, Chang JH, Su KY
Cell biology and toxicology 2024 Dec 30;41(1):20

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Pinocembrin alleviates LPS-induced depressive-like behavior in mice via the NLRP3/DCC signaling pathway.

Wu YL, Hu T, Zheng H, Feng J, Huang C, Zhou X, Wang W, Jiang CL
Biochemical and biophysical research communications 2024 Dec 3;736:150870

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Single-cell view and a novel protective macrophage subset in perivascular adipose tissue in T2DM.

Li J, Tian Z, Zhang T, Jin J, Zhang X, Xie P, Lin H, Gu J, Wu Y, Wang X, Zhang S, Yan X, Guo D, Wang Z, Zhang Q
Cellular & molecular biology letters 2024 Dec 3;29(1):148

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VPS28 regulates triglyceride synthesis via ubiquitination in bovine mammary epithelial cells.

Liu L, Wang J, Zheng X, Zhang Q
Scientific reports 2024 Dec 28;14(1):31310

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Single-nucleus transcriptomic profiling of the diaphragm during mechanical ventilation.

Li L, Jiang F, Hao W, Wang Y, Li Y, Zhang D
Scientific reports 2024 Dec 28;14(1):31181

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VZV IE4 downregulates cellular surface MHC-I via sequestering it to the Golgi complex.

Ye Y, Li S, Yan X, Zheng Q, Xue M, Wang H, Zheng C
Cellular and molecular life sciences : CMLS 2024 Dec 27;82(1):23

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Therapeutic potential of microglial SMEK1 in regulating H3K9 lactylation in cerebral ischemia-reperfusion.

Si WY, Yang CL, Wei SL, Du T, Li LK, Dong J, Zhou Y, Li H, Zhang P, Liu QJ, Duan RS, Duan RN
Communications biology 2024 Dec 26;7(1):1701

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Macrophage NLRP3-dependent IL-1β production contributes to aortic fibrosis in heart failure with preserved ejection fraction.

Chen S, Lu Z
Acta biochimica et biophysica Sinica 2024 Dec 26;57(7):1175-1183

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Activated DRP1 promotes mitochondrial fission and induces glycolysis in ATII cells under hyperoxia.

Sun T, Yu H, Zhang D, Li D, Fu J
Respiratory research 2024 Dec 26;25(1):443

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USP44 regulates HEXIM1 stability to inhibit tumorigenesis and metastasis of oral squamous cell carcinoma.

Chen S, Wu K, Zong Y, Hou Z, Deng Z, Xia Z
Biology direct 2024 Dec 26;19(1):143

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CTSG is a prognostic marker involved in immune infiltration and inhibits tumor progression though the MAPK signaling pathway in non-small cell lung cancer.

Dai Q, Yao X, Zhang Y, Chai Q, Feng X, Zhu H, Zhao L
Journal of cancer research and clinical oncology 2024 Dec 26;151(1):21

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Gegen Qinlian Decoction Attenuates Colitis-Associated Colorectal Cancer via Suppressing TLR4 Signaling Pathway Based on Network Pharmacology and In Vivo/In Vitro Experimental Validation.

Xu Y, Cai Q, Zhao C, Zhang W, Xu X, Lin H, Lin Y, Chen D, Lin S, Jia P, Wang M, Zhang L, Lin W
Pharmaceuticals (Basel, Switzerland) 2024 Dec 25;18(1)

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Pyroptosis mediated by Parkin-NLRP3 negative feedback loop contributed to Parkinson's disease induced by rotenone.

Zheng D, Lai Y, Huang K, Guan D, Xie Z, Fu C, Liu L, Huang J, Gong L, Li J, Zhang H, Chen J
International immunopharmacology 2024 Dec 25;143(Pt 3):113608

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Snake venom weakens neurovascular integrity and promotes vulnerability to neuroinflammation.

Feng Z, Fang C, Yu M, Wang Y, Abiola OF, Lin J, Liu Y, Zeng Z, Zeng L, Mo Z, Ma Y
International immunopharmacology 2024 Dec 25;143(Pt 3):113586

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Nicorandil restores endothelial cell Kir6.2 expression to alleviate neuropathic pain in mice after chronic constriction injury.

Du M, Li J, Ren X, Zhao J, Miao Y, Lu Y
International immunopharmacology 2024 Dec 25;143(Pt 2):113494

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Restoration of RECK expression attenuates liver fibrosis induced by carbon tetrachloride through the Nrf2-MMP9 axis.

Wei B, Huang J, Zhang Y, Hu X, Ma C, Li Y, Chen P
International immunopharmacology 2024 Dec 25;143(Pt 2):113475

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Colorectal cancer cells establish metabolic reprogramming with cancer-associated fibroblasts (CAFs) through lactate shuttle to enhance invasion, migration, and angiogenesis.

Wang X, Qu Y, Ji J, Liu H, Luo H, Li J, Han X
International immunopharmacology 2024 Dec 25;143(Pt 2):113470

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Quercetin inhibits mitophagy-mediated apoptosis and inflammatory response by targeting the PPARγ/PGC-1α/NF-κB axis to improve acute liver failure.

Wu H, Wu L, Luo L, Wu YT, Zhang QX, Li HY, Zhang BF
International immunopharmacology 2024 Dec 25;143(Pt 2):113444

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The triple combination DBDx alleviates cytokine storm and related lung injury.

Yu Z, Li Y, Bai L, Zheng Y, Liu X, Zhen Y
International immunopharmacology 2024 Dec 25;143(Pt 2):113431

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Corilagin inhibits human cytomegalovirus infection and replication via activating the cGAS-STING signaling pathway in vitro and in vivo.

Xie J, Shang L, Liu C, Mao J, He C, Luo M, Fisher D, Thi Thu Hien N, Xu S, Zhao L
International immunopharmacology 2024 Dec 25;143(Pt 2):113401

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Isoamericanin A ameliorates neuronal damage and alleviates vascular cognitive impairments by inhibiting oxidative stress through activation of the Nrf2 pathway.

Yang Y, Xu L, Yao X, Wang Y, Fang M, Zhou D, Li N, Hou Y
International immunopharmacology 2024 Dec 25;143(Pt 1):113366

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Single-cell sequencing in diffuse large B-cell lymphoma: C1qC is a potential tumor-promoting factor.

Gao G, Sun N, Zhang Y, Li J, Jiang Y, Chen N, Tang Y, Shi W
International immunopharmacology 2024 Dec 25;143(Pt 1):113319

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Curcumin activates the Wnt/β-catenin signaling pathway to alleviate hippocampal neurogenesis abnormalities caused by intermittent hypoxia: A study based on network pharmacology and experimental verification.

He Y, Zhao Y, Lv RJ, Dong N, Wang X, Yu Q, Yue HM
International immunopharmacology 2024 Dec 25;143(Pt 1):113299

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Isolicoflavonol ameliorates acute liver injury via inhibiting NLRP3 inflammasome activation through boosting Nrf2 signaling in vitro and in vivo.

Zhang XJ, Pu YK, Yang PY, Wang MR, Zhang RH, Li XL, Xiao WL
International immunopharmacology 2024 Dec 25;143(Pt 1):113233

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Molecular module for glucose production influences sex pheromone synthesis in Bactrocera dorsalis.

Li X, Wang Z, Chen J, Teng H, Yang X, Ye L, Jiang Y, Chen H, Cheng D, Lu Y
Cell reports 2024 Dec 24;43(12):115030

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Carbonic anhydrase 2 facilitates sorafenib resistance by counteracting MCT4-mediated intracellular pH dysregulation in HCC.

Lu H, Liu H, Yan R, Ma W, Liu H, Liu R, Sun Y, Ye L, Gao P, Jia W, Zhang P, Zhang H
Cell reports 2024 Dec 24;43(12):114996

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ACSS1-dependent acetate utilization rewires mitochondrial metabolism to support AML and melanoma tumor growth and metastasis.

Hlavaty SI, Salcido KN, Pniewski KA, Mukha D, Ma W, Kannan T, Cassel J, Srikanth YVV, Liu Q, Kossenkov A, Salvino JM, Chen Q, Schug ZT
Cell reports 2024 Dec 24;43(12):114988

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Hypoxia Promotes Osteoclast Differentiation by Weakening USP18-Mediated Suppression on the NF-κB Signaling Pathway.

Fan X, Li B, Chai S, Zhang R, Cai C, Ge R
International journal of molecular sciences 2024 Dec 24;26(1)

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Sphk1/S1P pathway promotes blood-brain barrier breakdown after intracerebral hemorrhage through inducing Nlrp3-mediated endothelial cell pyroptosis.

Feng M, An Y, Qin Q, Fong IH, Zhang K, Wang F, Song D, Li M, Yu M, Yeh CT, Chang J, Guo F
Cell death & disease 2024 Dec 23;15(12):926

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Brain derived β-interferon is a potential player in Alzheimer's disease pathogenesis and cognitive impairment.

Wang Q, Yuan S, Wang C, Huang D, Zhang M, Zhan Y, Gao F, Shi J, Levey AI, Shen Y
Alzheimer's research & therapy 2024 Dec 21;16(1):271

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Identification of UNC5B as a novel aggressive biomarker for osteosarcoma based on basement membrane genes.

Pan R, Zhang Y, Cheng Y, Wu Z, Liu J, Chen Z, Wang J, Zhang X, Wang H, Feng S, Zheng X
Gene 2024 Dec 20;930:148871

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Ginsenoside Rg1 improves cigarette smoke-induced ferroptosis in COPD by regulating PERK/ATF4 axis to inhibit endoplasmic reticulum stress.

Tan W, Liang Z, Tan X, Tan G
Biochemical and biophysical research communications 2024 Dec 20;739:150946

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African swine fever virus enhances viral replication by increasing intracellular reduced glutathione levels, which suppresses stress granule formation.

Gao H, Gu T, Gao X, Song Z, Liu J, Song Y, Zhang G, Sun Y
Veterinary research 2024 Dec 20;55(1):172

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1,2-Propanediol Attenuates Radiation-Induced HaCaT Cell Injury by Inhibiting Oxidative Stress.

Liu Y, Ren B, Liu Y, Li Q, Jin J, Wu CT, Zhou G, Jin J
Biomedical and environmental sciences : BES 2024 Dec 20;37(12):1447-1452

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HDAC10 switches NLRP3 modification from acetylation to ubiquitination and attenuates acute inflammatory diseases.

Yang M, Qin Z, Lin Y, Ma D, Sun C, Xuan H, Cui X, Ma W, Zhu X, Han L
Cell communication and signaling : CCS 2024 Dec 20;22(1):615

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Salivary gland protective and antiinflammatory effects of genistein in Sjögren's syndrome by inhibiting Xist/ACSL4-mediated ferroptosis following binding to estrogen receptor-alpha.

Mao T, Wei W, Chen B, Chen Y, Liang S, Chen G, Liu Z, Wu X, Wu L, Li X, Watanabe N, Mayo KH, Pathak JL, Li J
Cellular & molecular biology letters 2024 Dec 2;29(1):147

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Sec23IP recruits VPS13B/COH1 to ER exit site-Golgi interface for tubular ERGIC formation.

Du Y, Fan X, Song C, Chang W, Xiong J, Deng L, Ji WK
The Journal of cell biology 2024 Dec 2;223(12)

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Necrosis drives susceptibility to Mycobacterium tuberculosis in Polg(D257A) mutator mice.

Mabry CJ, Weindel CG, Stranahan LW, VanPortfliet JJ, Davis JR, Martinez EL, West AP, Patrick KL, Watson RO
bioRxiv : the preprint server for biology 2024 Dec 2;

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Chemerin attenuates acute kidney injury by inhibiting ferroptosis via the AMPK/NRF2/SLC7A11 axis.

Ma Y, Fei S, Chen X, Gui Y, Zhou B, Xiang T, Liu J, Yue K, Li Q, Jiang W, Sun C, Huang X
Communications biology 2024 Dec 19;7(1):1679

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The therapeutic effect of DX2 inhibition in nicotine-induced lung cancer progression.

Park S, Oh AY, Hong BS, Shin YJ, Jang H, Seo H, Kang SM, Woo TG, Park HP, Jeong J, Kim HJ, Kim BH, Kwon Y, Park BJ
Molecular therapy. Oncology 2024 Dec 19;32(4):200875

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Full-length direct RNA sequencing uncovers stress granule-dependent RNA decay upon cellular stress.

Dar SA, Malla S, Martinek V, Payea MJ, Lee CT, Martin J, Khandeshi AJ, Martindale JL, Belair C, Maragkakis M
eLife 2024 Dec 19;13

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17β-estradiol alleviated ferroptotic neuroinflammation by suppressing ATF4 in mouse model of Parkinson's disease.

Wang G, Zhuang W, Zhou Y, Wang X, Li Z, Liu C, Li W, He M, Lv E
Cell death discovery 2024 Dec 19;10(1):507

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Circadian Rhythm Enhances mTORC1/AMPK Pathway-Mediated Milk Fat Synthesis in Dairy Cows via the Microbial Metabolite Acetic Acid.

Jiang X, Geng H, Zhang C, Zhu Y, Zhu M, Feng D, Wang D, Yao J, Deng L
Journal of agricultural and food chemistry 2024 Dec 18;72(50):28178-28193

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Myricetin Alleviates Silica-Mediated Lung Fibrosis via PPARγ-PGC-1α Loop and Suppressing Mitochondrial Senescence in Epithelial Cells.

Xie W, Deng L, Zhang X, Huang X, Ding J, Liu W, Tang SY
Journal of agricultural and food chemistry 2024 Dec 18;72(50):27737-27749

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LOC730101 improves ovarian cancer drug sensitivity by inhibiting autophagy-mediated DNA damage repair via BECN1.

Zhong Y, Shuai Y, Yang J, Zhang M, He T, Zheng L, Yang S, Peng S
Cell death & disease 2024 Dec 18;15(12):893

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NIR-715 photodynamic therapy induces immunogenic cancer cell death by enhancing the endoplasmic reticulum stress response.

Zheng ZY, Lin W, Su JW, Huang QF, Zhang C, Pan WX, Li EM, Zhang HF, Xu LY
Cell death & disease 2024 Dec 18;15(12):890

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Identification of potential biomarkers for hepatocellular carcinoma based on machine learning and bioinformatics analysis.

Chen C, Peng R, Jin S, Tang Y, Liu H, Tu D, Su B, Wang S, Jiang G, Cao J, Zhang C, Bai D
Discover oncology 2024 Dec 18;15(1):808

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RRM1 promotes homologous recombination and radio/chemo-sensitivity via enhancing USP11 and E2F1-mediated RAD51AP1 transcription.

Yang S, Wang R, Liu L, Xu F, Zhao X, Yao Z, Zhang J, Cheng X, Xu A, Wu L, Zhao G
Cell death discovery 2024 Dec 18;10(1):496

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SLC50A1 inhibits the doxorubicin sensitivity in hepatocellular carcinoma cells through regulating the tumor glycolysis.

Wang G, Jin W, Zhang L, Dong M, Zhang X, Zhou Z, Wang X
Cell death discovery 2024 Dec 18;10(1):495

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Chemical activation of mitochondrial ClpP to modulate energy metabolism of CD4(+) T cell for inflammatory bowel diseases treatment.

Zhang J, Jiang Y, Fan D, Qiu Z, He X, Liu S, Li L, Dai Z, Zhang L, Shu Z, Li L, Zhang H, Yang T, Luo Y
Cell reports. Medicine 2024 Dec 17;5(12):101840

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Structure-guided development of selective caseinolytic protease P agonists as antistaphylococcal agents.

Zhang T, Wang P, Zhou H, Wei B, Zhao Y, Li J, Zhang M, Wu W, Lan L, Gan J, Yang CG
Cell reports. Medicine 2024 Dec 17;5(12):101837

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Phosphocholine inhibits proliferation and reduces stemness of endometrial cancer cells by downregulating mTOR-c-Myc signaling.

Gong K, Zheng Y, Liu Y, Zhang T, Song Y, Chen W, Guo L, Zhou J, Liu W, Fang T, Chen Y, Wang J, Pan F, Shi K
Cellular and molecular life sciences : CMLS 2024 Dec 16;82(1):3

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Selectively targeting the AdipoR2-CaM-CaMKII-NOS3 axis by SCM-198 as a rapid-acting therapy for advanced acute liver failure.

Wang R, Chen Y, Han J, Ye H, Yang H, Li Q, He Y, Ma B, Zhang J, Ge Y, Wang Z, Sun B, Liu H, Cheng L, Wang Z, Lin G
Nature communications 2024 Dec 16;15(1):10690

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MitoQ enhances CYP19A1 expression to stimulate WNT/β-catenin signaling pathway for promoting hair growth in androgenetic alopecia.

Li Y, Dong T, Yang F, Jin S, Xiong R, Song X, Guan C
European journal of pharmacology 2024 Dec 15;985:177094

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Demyelination in cuprizone mice is ameliorated by calycosin mediated through astrocyte Nrf2 signaling pathway.

Chen Y, Wang Y, Lu Q, Zhao Y, Cruz J, Ma J, Ding G, Qiao X, Cheng X
European journal of pharmacology 2024 Dec 15;985:177090

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miR-421-mediated suppression of FGF13 as a novel mechanism ameliorates cardiac hypertrophy by inhibiting endoplasmic reticulum stress.

Zhi Y, Duan Y, Zhang Y, Hu H, Hu F, Wang P, Liu B, Wang C, Liu D, Gu G
European journal of pharmacology 2024 Dec 15;985:177085

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Integrated metabolomics and network pharmacology analysis to reveal the protective effect of Complanatoside A on nonalcoholic fatty liver disease.

Jiang S, Fan X, Hua J, Liu S, Feng Y, Shao D, Shen Y, Wang Z, Yan X, Wang J
European journal of pharmacology 2024 Dec 15;985:177074

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Transcription factor PRRX1-activated ANXA6 facilitates EGFR-PKCα complex formation and enhances cisplatin sensitivity in bladder cancer.

Cao J, Chen S, Wang J, Fan X, Liu S, Li X, Yang L
Life sciences 2024 Dec 15;359:123228

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Melatonin protects against particulate matter-induced ovarian dysfunction by activating the Nrf2 signaling pathway to alleviate ferroptosis.

Zhang X, Man X, Zhang Q, Zhu L, Chen L, Zhu C, Ci X, Yu X
Life sciences 2024 Dec 15;359:123200

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Dihydromyricetin-loaded oxidized polysaccharide/L-arginine chitosan adhesive hydrogel promotes bone regeneration by regulating PI3K/AKT signaling pathway and MAPK signaling pathway.

Yang J, Zhang L, Wang Y, Wang N, Wei H, Zhang S, Ding Q, Sun S, Ding C, Liu W
Carbohydrate polymers 2024 Dec 15;346:122614

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Neuritin attenuates neuroinflammation and apoptosis in early brain injury after subarachnoid hemorrhage via endoplasmic reticulum stress-related inflammatory pathways.

Ren K, Dai L, Zhang H, He Y, Liu B, Hu Y, Ma K, Tian W, Zhao D
Brain research 2024 Dec 15;1845:149293

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The Phenotype Changes of Astrocyte During Different Ischemia Conditions.

Meng F, Cui J, Wang P, Wang J, Sun J, Li L
Brain sciences 2024 Dec 14;14(12)

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SMG5, a component of nonsense-mediated mRNA decay, is essential for the mouse spermatogonial differentiation and maintenance.

Tan X, Chen C, Gao X, Wang H, Zhang Y, Li T
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Dec 13;38(24):e70268

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TBC1D15 Inhibits Autophagy of Microglia through Maintaining the Damaged Swelling Lysosome in Alzheimer's Disease.

Wu Y, Zhou YM, Wu W, Jiang WR, Zhang XY, Song SY, Yao ZH
Aging and disease 2024 Dec 13;16(6):3601-3624

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Development of Novel Silicon-Based Hydrophobic Tags (SiHyT) for Targeted Proteins Degradation.

Ma L, Zhang K, Huang Z, Guo Y, Liu N, Chen J, Wang X, Liu Y, Li M, Li J, Yang C, Liu S, Yang G
Journal of medicinal chemistry 2024 Dec 12;67(23):21344-21363

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Acetylation-Mediated Post-Translational Modification of Pyruvate Dehydrogenase Plays a Critical Role in the Regulation of the Cellular Acetylome During Metabolic Stress.

Rajakumar A, Nguyen S, Ford N, Ogundipe G, Lopez-Nowak E, Kondrachuk O, Gupta MK
Metabolites 2024 Dec 12;14(12)

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Effects of ginger root extract on cognitive impairment and the Nrf2/GPX4/SLC7A11 signaling pathway in aluminum-exposed rats.

Qin L, Jiang X, Wei Y, Xie J, Yang L
Metabolic brain disease 2024 Dec 11;40(1):60

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Zinc promotes microbial p-coumaric acid production that protects against cholestatic liver injury.

Li D, Wan M, Xue L, Zhang Z, Qiu Y, Mei F, Tang N, Yu C, Yu Y, Chen T, Ding X, Yang Q, Liu Q, Gu P, Jia W, Chen Y, Chen P
Cell host & microbe 2024 Dec 11;32(12):2195-2211.e9

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Identification of NECTIN1 as a novel restriction factor for flavivirus infection.

Qi S, Sun C, Wang J, Wo L, Li Y, Wang C, Zhang Y, Bian H, Guo Y, Gao M, Wang M, Tang Y, Zhu Y, Xue F, Pang Q, Jiang Z, Yin X
mBio 2024 Dec 11;15(12):e0270824

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The vitamin D receptor is essential for the replication of pseudorabies virus.

Zeng L, Wang S-Y, Du M-H, Chu B-B, Ming S-L
mBio 2024 Dec 11;15(12):e0213724

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The essential role of TTC28 in maintaining chromosomal stability via HSPA8 chaperone-mediated autophagy.

Zhang G, Xiang M, Gu L, Zhou J, Zhang B, Tian W, Deng D
Proceedings of the National Academy of Sciences of the United States of America 2024 Dec 10;121(50):e2409447121

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METTL3/YTHDF1 stabilizes CORO6 expression promoting osteosarcoma progression through glycolysis.

Liu X, Yu W, Song W, Zhang Z, Chen B, Lin H
Experimental cell research 2024 Dec 1;443(2):114328

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Pim1 is Critical in T-cell-independent B-cell Response and MAPK Activation in B Cells.

Cui D, Zhang Y, Zheng B, Chen L, Wei J, Lin D, Huang M, Du H, Chen Q
Journal of molecular biology 2024 Dec 1;436(23):168824

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Oxymatrine inhibits migration and invasion of esophageal squamous cell carcinoma cell lines via the MEK1/ERK/β-catenin pathway.

Xu B, Qiu T, Yang R, Qiang J, Yang Y, Zhou M, Li X, Dong J, Lu Y, Dong Z
Chemico-biological interactions 2024 Dec 1;404:111270

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Prenatal exposure to environmentally relevant levels of PAHs inhibits spermatogenesis in adult mice and the mechanism involved.

Ou K, Zhang S, Lei X, Liu X, Zhang N, Wang C, Yuan X
Environmental pollution (Barking, Essex : 1987) 2024 Dec 1;362:124914

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Exosomes from human bone marrow MSCs alleviate PD-1/PD-L1 inhibitor-induced myocardial injury in melanoma mice by regulating macrophage polarization and pyroptosis.

Zhou B, Qin Q, Fang Y, Liu X, Zhang M, Wang S, Zhong L, Guo R
Life sciences 2024 Dec 1;358:123108

---

Borg5 restricts contractility and motility in epithelial MDCK cells.

Cohen D, Fernandez D, Lázaro-Diéguez F, Überheide B, Müsch A
Journal of cell science 2024 Dec 1;137(23)

---

In utero morphological and functional properties of bovine trophoblastic vesicles.

Kagawa S, Hayashi Y, Bai H, Takahashi M, Kawahara M
Molecular reproduction and development 2024 Aug;91(8):e23767

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Quercetin inhibits hypertonicity-induced inflammatory injury in human corneal epithelial cells via the PTEN/PI3K/AKT pathway.

Huang Y, Xia X, Li M, Li D, Xie S, Li J, Yang Y, Peng Q
Tissue & cell 2024 Aug;89:102465

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Inhibition of the TCF12/VSIG4 axis by palbociclib diminishes the proliferation and migration of glioma cells and decreases the M2 polarization of glioma-associated microglia.

Li C, Li R, Wang Y, Jiang H
Drug development research 2024 Aug;85(5):e22230

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Pyrroloquinoline quinone protects against murine hepatitis virus strain 3-induced fulminant hepatitis by inhibiting the Keap1/Nrf2 signaling.

Pu Z, Ge F, Zhou Y, Liu A, Yang C
Cytotechnology 2024 Aug;76(4):441-452

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Mitochondria-targeted catalase induced cell malignant transformation by the downregulation of p53 protein stability via USP28/miR-200b/PP2A-Cα axis.

Wen C, Huang C, Liao X, Luo Z, Huang C
Archives of biochemistry and biophysics 2024 Aug;758:110047

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Homozygous variant in DRC3 (LRRC48) gene causes asthenozoospermia and male infertility.

Qin J, Wang J, Chen J, Xu J, Liu S, Deng D, Li F
Journal of human genetics 2024 Aug;69(8):401-409

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Deficiency of betaine-homocysteine methyltransferase activates glucose-6-phosphate dehydrogenase (G6PD) by decreasing arginine methylation of G6PD in hepatocellular carcinogenesis.

Gao J, Shi X, Sun Y, Liu X, Zhang F, Shi C, Yu X, Yan Z, Liu L, Yu S, Zhang J, Zhang X, Zhang S, Guo W
Science China. Life sciences 2024 Aug;67(8):1648-1665

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The combination of Butyricicoccus pullicaecorum and 3-hydroxyanthranilic acid prevents postmenopausal osteoporosis by modulating gut microbiota and Th17/Treg.

Zhu F, Liu H, Cao Y, Dai B, Wu H, Li W
European journal of nutrition 2024 Aug;63(5):1945-1959

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Propofol Mitigates Sepsis-Induced Brain Injury by Inhibiting Ferroptosis Via Activation of the Nrf2/HO-1axis.

Zhou Y, Yang Y, Yi L, Pan M, Tang W, Duan H
Neurochemical research 2024 Aug;49(8):2131-2147

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AdipoRon Ameliorates Synaptic Dysfunction and Inhibits tau Hyperphosphorylation through the AdipoR/AMPK/mTOR Pathway in T2DM Mice.

Zhao W, Zhang W, Hu Y, Zhou Y, Zhao J, Li Y, Xu Z
Neurochemical research 2024 Aug;49(8):2075-2086

---

Serum IL-24 combined with CA125 as screening and prognostic biomarkers for NSCLC.

Zhang K, Qu J, Deng S, Yuan E
Cell biology international 2024 Aug;48(8):1160-1168

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Succinylation of 14-3-3 theta by CPT1A promotes survival and paclitaxel resistance in nasal type extranodal natural killer/T-cell lymphoma.

Cui X, Cao C, Li X, Lin B, Yan A, Yang Y
Translational oncology 2024 Aug;46:102006

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Empagliflozin and liraglutide ameliorate HFpEF in mice via augmenting the Erbb4 signaling pathway.

Ni XY, Feng XJ, Wang ZH, Zhang Y, Little PJ, Cao Y, Xu SW, Tang LQ, Weng JP
Acta pharmacologica Sinica 2024 Aug;45(8):1604-1617

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Baicalein suppresses Coxsackievirus B3 replication by inhibiting caspase-1 and viral protease 2A.

Dong Y, Shao E, Li S, Wang R, Wang D, Wang L, Yang H, He Y, Luan T, Chen Y, Wang Y, Lin L, Wang Y, Zhong Z, Zhao W
Virologica Sinica 2024 Aug;39(4):685-693

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Tamarixetin ameliorates cerebral ischemia-reperfusion injury via suppressing nicotinamide adenine dinucleotide phosphate oxidase 2/nucleotide-binding oligomerization domain like receptor family pyrin domain-containing 3 inflammasome activation.

Yang Y, Wang F, Fang M, Yao X, Xu L, Liu Y, Liu Y, Liang D, Zeng K, Li N, Hou Y
Phytotherapy research : PTR 2024 Aug;38(8):4286-4306

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Maresin1 alleviates neuroinflammation by inhibiting caspase-3/ GSDME-mediated pyroptosis in mice cerebral ischemia-reperfusion model.

Zhao M, Xian W, Liu W, Chen D, Wang S, Cao J
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2024 Aug;33(8):107789

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miR-107 reverses the multidrug resistance of gastric cancer by targeting the CGA/EGFR/GATA2 positive feedback circuit.

Wang P, Zhou Y, Wang J, Zhou Y, Zhang X, Liu Y, Li A, He Y, Chen S, Qian A, Wang X, Nie Y, Fan D, Cao T, Lu Y, Zhao X
The Journal of biological chemistry 2024 Aug;300(8):107522

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Neuroprotective Effect and Mechanism of Tanreqing Injection on Ischemic Stroke: Insights from Network Pharmacology and in vivo Experiments.

Li ZH, Pu XQ, Li SS, Dong XK, Zhang GQ, Wang Y, Liu JM
Chinese journal of integrative medicine 2024 Aug;30(8):713-720

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Ribosome stalling during c-myc translation presents actionable cancer cell vulnerability.

Khaket TP, Rimal S, Wang X, Bhurtel S, Wu YC, Lu B
PNAS nexus 2024 Aug;3(8):pgae321

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Nonstructural protein 14 of PDCoV promotes complement C3 expression via the activation of p38-MAPK-C/EBP pathway.

Chen Z, Zhong C, Fan L, Shang H, Xiao L, Wang W, Guo R, Fan B, Li J, Li B
Veterinary microbiology 2024 Aug;295:110137

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Identifying SLC2A6 as the novel protective factor in breast cancer by TP53-related genes affecting M1 macrophage infiltration.

Dai C, Man Y, Zhang L, Zhang X, Xie C, Wang S, Zhang Y, Guo Q, Zou L, Hong H, Jiang L, Shi Y
Apoptosis : an international journal on programmed cell death 2024 Aug;29(7-8):1211-1231

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IGFBP2 induces podocyte apoptosis promoted by mitochondrial damage via integrin α5/FAK in diabetic kidney disease.

Wang X, Zhang Y, Chi K, Ji Y, Zhang K, Li P, Fu Z, Wang X, Cui S, Shen W, Cai G, Chen X, Zhu H, Hong Q
Apoptosis : an international journal on programmed cell death 2024 Aug;29(7-8):1109-1125

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Embryo injected with Ochratoxin A induced jejunum injury in ducklings by activating the TLR4 signaling pathway: Involvement of intestinal microbiota.

Peng X, Fan H, Liu J, Jiang X, Liu C, Yang Y, Zhai S
Ecotoxicology and environmental safety 2024 Aug;281:116666

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Contribution of Tregs to the promotion of constructive remodeling after decellularized extracellular matrix material implantation.

Jiang H, Sun X, Wu Y, Xu J, Xiao C, Liu Q, Fang L, Liang Y, Zhou J, Wu Y, Lin Z
Materials today. Bio 2024 Aug;27:101151

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Blue light irradiation suppresses oral squamous cell carcinoma through induction of endoplasmic reticulum stress and mitochondrial dysfunction.

Jiang H, Fu Q, Yang J, Qin H, Li A, Liu S, Liu M
Journal of photochemistry and photobiology. B, Biology 2024 Aug;257:112963

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Lactate-induced metabolic remodeling and myofiber type transitions via activation of the Ca(2+)-NFATC1 signaling pathway.

Zhou Y, Liu X, Qi Z, Huang C, Yang L, Lin D
Journal of cellular physiology 2024 Aug;239(8):e31290

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Homoplantaginin alleviates intervertebral disc degeneration by blocking the NF-κB/MAPK pathways via binding to TAK1.

Li B, Hu Y, Chen Y, Liu K, Rong K, Hua Q, Fu S, Yang X, Zhou T, Cheng X, Zhang K, Zhao J
Biochemical pharmacology 2024 Aug;226:116389

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Mesenchymal stem cell-derived exosomes ameliorate hypoxic pulmonary hypertension by inhibiting the Hsp90aa1/ERK/pERK pathway.

Deng ZH, Chen YX, Xue-Gao, Yang JY, Wei XY, Zhang GX, Qian JX
Biochemical pharmacology 2024 Aug;226:116382

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TRAF6-mediated ubiquitination of AKT1 in the nucleus occurs in a β-arrestin2-dependent manner upon insulin stimulation.

Hu L, Liu H, Ma H, Zeng X, Cao Y, Liu B, Li H, Zhang X
Biochemical pharmacology 2024 Aug;226:116362

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Ubiquitin-specific peptidase 15 regulates the TFAP4/PCGF1 axis facilitating liver metastasis of colorectal cancer and cell stemness.

Yin H, Wu D, Qu Q, Li Z, Zhao L
Biochemical pharmacology 2024 Aug;226:116319

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EGFR-MEK1/2 cascade negatively regulates bactericidal function of bone marrow macrophages in mice with Staphylococcus aureus osteomyelitis.

Jin M, Wu X, Hu J, Chen Y, Yang B, Cheng C, Yang M, Zhang X
PLoS pathogens 2024 Aug;20(8):e1012437

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Human Umbilical Cord Mesenchymal Stem Cells Promote Anti-Inflammation and Angiogenesis by Targeting Macrophages in a Rat Uterine Scar Model.

Yang Q, Huang J, Liu Y, Mai Q, Zhou Y, Zhou L, Zeng L, Deng K
Stem cell reviews and reports 2024 Aug;20(6):1555-1568

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FeP-Based Nanotheranostic Platform for Enhanced Phototherapy/Ferroptosis/Chemodynamic Therapy.

An N, Tang S, Wang Y, Luan J, Shi Y, Gao M, Guo C
Small (Weinheim an der Bergstrasse, Germany) 2024 Aug;20(32):e2309940

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Cyanidin-3-O-glucoside alleviates ethanol-induced liver injury by promoting mitophagy in a Gao-binge mouse model of alcohol-associated liver disease.

He Q, Yin Z, Chen Y, Wu Y, Pan D, Cui Y, Zhang Z, Ma H, Li X, Shen C, Qin J, Wang S
Biochimica et biophysica acta. Molecular basis of disease 2024 Aug;1870(6):167259

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Development and Comparative Study of a Mouse Model of Airway Inflammation and Remodeling Induced by Exosomes Derived from Bone Marrow Mesenchymal Stem Cells.

Yao B, Liu J, Xie J, Li Z, Luo Y, Wang M
Bulletin of experimental biology and medicine 2024 Aug;177(4):544-551

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Graveoline attenuates D-GalN/LPS-induced acute liver injury via inhibition of JAK1/STAT3 signaling pathway.

He J, Feng X, Liu Y, Wang Y, Ge C, Liu S, Jiang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117163

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Tanshinone I improves TNBC chemosensitivity by suppressing late-phase autophagy through AKT/p38 MAPK signaling pathway.

Tang X, Gong J, Ren L, Wang Z, Yang B, Wang W, Wang N
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117037

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Lipoamide Attenuates Hypertensive Myocardial Hypertrophy Through PI3K/Akt-Mediated Nrf2 Signaling Pathway.

Cao H, Zhao L, Yuan Y, Liao C, Zeng W, Li A, Huang Q, Zhao Y, Fan Y, Jiang L, Song D, Li S, Zhang B
Journal of cardiovascular translational research 2024 Aug;17(4):910-922

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Integrated multi-omics profiling landscape of organising pneumonia.

Tang Y, Chu C, Bu S, Sun Q, Liu A, Xie J, Qiao S, Huang L, Wang H
Clinical and translational medicine 2024 Aug;14(8):e1782

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Proteomic analysis of the effects of Dictyophora polysaccharide on arsenic-induced hepatotoxicity in rats.

Yan X, Chen X, Zhang X, Qureshi A, Wang Y, Tang X, Hu T, Zhuang H, Ran X, Ma G, Luo P, Shen L
Experimental and molecular pathology 2024 Aug;138:104910

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Guizhi Shaoyao Zhimu Decoction ameliorates gouty arthritis in rats via altering gut microbiota and improving metabolic profile.

Bian M, Zhu C, Nie A, Zhou Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Aug;131:155800

---

Hypobaric hypoxia causes low fecundity in zebrafish parents and impairment of skeletal development in zebrafish embryos and rat offspring.

Chen C, Wang X, Li Y, Zhao T, Wang H, Gao Y, Feng Y, Wang J, Shang L, Wang Y, Zhao B, Dong W
Reproductive toxicology (Elmsford, N.Y.) 2024 Aug;127:108603

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Microbial reconstitution reverses prenatal stress-induced cognitive impairment and synaptic deficits in rat offspring.

Chen J, Zeng R, Chen H, Cao M, Peng Y, Tong J, Huang J
Brain, behavior, and immunity 2024 Aug;120:231-247

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mRNA-Lipid Nanoparticle-Mediated Restoration of PTPN14 Exhibits Antitumor Effects by Overcoming Anoikis Resistance in Triple-Negative Breast Cancer.

Li W, Huang M, Wu Z, Zhang Y, Cai Y, Su J, Xia J, Yang F, Xiao D, Yang W, Xu Y, Liu Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(32):e2309988

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Reversing MET-Mediated Resistance in Oncogene-Driven NSCLC by MET-Activated Wnt Condensative Prodrug.

Liu N, Zheng X, Yan J, Jiang A, Yao Y, He W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(30):e2400603

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Gut Dysbiosis Drives Inflammatory Bowel Disease Through the CCL4L2-VSIR Axis in Glycogen Storage Disease.

Lan J, Zhang Y, Jin C, Chen H, Su Z, Wu J, Ma N, Zhang X, Lu Y, Chen Y, Zeng X, Zhang H, Zheng G, Sun Y, Wang C, Hu Y, Wang Y, Liu Y, Zeng Z, Shi L, He J, Cao A, Wang Y, Pan X, Jin G, Wang Y, Jiang X, Shen H, Tang Q, Xie X, Xiao Y, Zhong X, Zhang X, Zeng L, Ye L, Xie J, Geng L, Li Z, Wu X, Wang Y, Mao R, Zhang S, Huang S, Liu S, Zeng H, Xu W, Gong S, Guo Y, Yang M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(30):e2309471

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CD147-K148me2-Driven Tumor Cell-Macrophage Crosstalk Provokes NSCLC Immunosuppression via the CCL5/CCR5 Axis.

Wang K, Chen X, Lin P, Wu J, Huang Q, Chen ZN, Tian J, Wang H, Tian Y, Shi M, Qian M, Hui B, Zhu Y, Li L, Yao R, Bian H, Zhu P, Chen R, Chen L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(29):e2400611

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Polydopamine Nanoparticles as Mimicking RPE Melanin for the Protection of Retinal Cells Against Blue Light-Induced Phototoxicity.

Kwon YS, Munsoor J, Kaufmann M, Zheng M, Smirnov AI, Han Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(29):e2400230

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TRIM24 Cooperates with Ras Mutation to Drive Glioma Progression through snoRNA Recruitment of PHAX and DNA-PKcs.

Xu C, Chen G, Yu B, Sun B, Zhang Y, Zhang M, Yang Y, Xiao Y, Cheng SY, Li Y, Feng H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(29):e2400023

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The Loss of an Orphan Nuclear Receptor NR2E3 Augments Wnt/β-catenin Signaling via Epigenetic Dysregulation that Enhances Sp1-β catenin-p300 Interactions in Hepatocellular Carcinoma.

Leung YK, Lee SG, Wang J, Guruvaiah P, Rusch NJ, Ho SM, Park C, Kim K
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(29):e2308539

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Loss of NLRP6 expression increases the severity of intestinal injury after syngeneic hematopoietic stem cell transplantation.

Zhu S, Zhang X, Xu K, Liang J, Wang W, Zeng L, Xu K
Annals of hematology 2024 Aug;103(8):3145-3154

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Epigallocatechin-3-gallate protects bovine ruminal epithelial cells against lipopolysaccharide-induced inflammatory damage by activating autophagy.

Zhao W, Shen T, Zhao B, Li M, Deng Z, Huo Y, Aernouts B, Loor JJ, Psifidi A, Xu C
Journal of animal science and biotechnology 2024 Aug 9;15(1):109

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The V-ATPase/ATG16L1 axis is controlled by the V(1)H subunit.

Timimi L, Wrobel AG, Chiduza GN, Maslen SL, Torres-Méndez A, Montaner B, Davis C, Minckley T, Hole KL, Serio A, Devine MJ, Skehel JM, Rubinstein JL, Schreiber A, Beale R
Molecular cell 2024 Aug 8;84(15):2966-2983.e9

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Discovery and Optimization of Hsp110 and sGC Dual-Target Regulators for the Treatment of Pulmonary Arterial Hypertension.

Hu Y, Zhao C, Tan W, Li M, Wang Y, Gao R, Chen Z, Jin Z, Hu L, Li Q
Journal of medicinal chemistry 2024 Aug 8;67(15):13474-13490

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Donor-Acceptor-Donor Strategy Rouses the Photodynamic Therapy Anticancer Activity of a Bis-terpyridyl Ru(II) Complex.

Wang Z, Wei L, Lin J, Huang C, Chen H, Fan D, Hu W, Liu J, Huang H, Wang Z, Wang X
Journal of medicinal chemistry 2024 Aug 8;67(15):13435-13445

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The WDR11 complex is a receptor for acidic-cluster-containing cargo proteins.

Deng H, Jia G, Li P, Tang Y, Zhao L, Yang Q, Zhao J, Wang J, Tu Y, Yong X, Zhang S, Mo X, Billadeau DD, Su Z, Jia D
Cell 2024 Aug 8;187(16):4272-4288.e20

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Schisandrin B alleviates testicular inflammation and Sertoli cell apoptosis via AR-JNK pathway.

Zhang BY, Yang R, Zhu WQ, Zhu CL, Chen LX, Zhao YS, Zhang Y, Wang YQ, Jiang DZ, Tang B, Zhang XM
Scientific reports 2024 Aug 8;14(1):18418

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Gut-derived memory γδ T17 cells exacerbate sepsis-induced acute lung injury in mice.

Xie B, Wang M, Zhang X, Zhang Y, Qi H, Liu H, Wu Y, Wen X, Chen X, Han M, Xu D, Sun X, Zhang X, Zhao X, Shang Y, Yuan S, Zhang J
Nature communications 2024 Aug 7;15(1):6737

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Quercetin-loaded Human Umbilical cord Mesenchymal Stem Cell-derived sEVs for Spinal Cord Injury Recovery.

Yang C, Xu T, Lu Y, Liu J, Chen C, Wang H, Chen X
Neuroscience 2024 Aug 6;552:14-28

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Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer.

Jiang Y, Wang Y, Chen G, Sun F, Wu Q, Huang Q, Zeng D, Qiu W, Wang J, Yao Z, Liang B, Li S, Wu J, Huang N, Wang Y, Chen J, Zhai X, Huang L, Xu B, Yamamoto M, Tsukamoto T, Nomura S, Liao W, Shi M
Cell metabolism 2024 Aug 6;36(8):1806-1822.e11

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Glycometabolic reprogramming-induced XRCC1 lactylation confers therapeutic resistance in ALDH1A3-overexpressing glioblastoma.

Li G, Wang D, Zhai Y, Pan C, Zhang J, Wang C, Huang R, Yu M, Li Y, Liu X, Liu Y, Wu F, Zhao Z, Hu H, Shi Z, Kahlert UD, Jiang T, Zhang W
Cell metabolism 2024 Aug 6;36(8):1696-1710.e10

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Chromatin Regulator SMARCA4 Is Essential for MHV-Induced Inflammatory Cell Death, PANoptosis.

Malireddi RKS, Kanneganti TD
Viruses 2024 Aug 6;16(8)

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PDCD4 triggers α-synuclein accumulation and motor deficits via co-suppressing TFE3 and TFEB translation in a model of Parkinson's disease.

Cao B, Chen X, Li Y, Zhou T, Chen N, Guo Y, Zhao M, Guo C, Shi Y, Wang Q, Du X, Zhang L, Li Y
NPJ Parkinson's disease 2024 Aug 6;10(1):146

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Atorvastatin ameliorates diabetic nephropathy through inhibiting oxidative stress and ferroptosis signaling.

Zhang Y, Qu Y, Cai R, Gao J, Xu Q, Zhang L, Kang M, Jia H, Chen Q, Liu Y, Ren F, Zhou MS
European journal of pharmacology 2024 Aug 5;976:176699

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Studies of Anticancer Activities In Vitro and In Vivo for Butyltin(IV)-Iridium(III) Imidazole-Phenanthroline Complexes with Aggregation-Induced Emission Properties.

Sun Y, Liu J, Li Q, Zhang X, Cao Z, Bu L, Cao S, Liu X, Yuan XA, Liu Z
Inorganic chemistry 2024 Aug 5;63(31):14641-14655

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Association of copy number variation in X chromosome-linked PNPLA4 with heterotaxy and congenital heart disease.

Gao H, Huang X, Chen W, Feng Z, Zhao Z, Li P, Tan C, Wang J, Zhuang Q, Gao Y, Min S, Yao Q, Qian M, Ma X, Wu F, Yan W, Sheng W, Huang G
Chinese medical journal 2024 Aug 5;137(15):1823-1834

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The influence of CLEC5A on early macrophage-mediated inflammation in COPD progression.

Li Q, Liu Y, Wang X, Xie C, Mei X, Cao W, Guan W, Lin X, Xie X, Zhou C, Yi E
Cellular and molecular life sciences : CMLS 2024 Aug 4;81(1):330

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Macrophage-derived extracellular vesicles represent a promising endogenous iron-chelating therapy for iron overload and cardiac injury in myocardial infarction.

Guo D, Yang X, Yu R, Geng J, Zhang X, Wang Y, Liang Q, Pu S, Peng T, Liu M, Fu F, Li Z, Hu L, Li Y
Journal of nanobiotechnology 2024 Aug 31;22(1):527

---

External pressure induces the dysfunction of spermatogonia via triggering the intrinsic pathway of apoptosis.

Liu Y, Sun Q, Du K, Long H, Zhang D, Zheng J, Zhao Y, Zhang H
Translational andrology and urology 2024 Aug 31;13(8):1405-1415

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Emodin attenuates hypoxic-ischemic brain damage by inhibiting neuronal apoptosis in neonatal mice.

Guo Y, Chen Y, Zhang H, Zhang Q, Jin M, Wang S, Du X, Du Y, Xu D, Wang M, Li L, Luo L
Neuroscience 2024 Aug 30;554:83-95

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ENG is a Biomarker of Prognosis and Angiogenesis in Liver Cancer, and Promotes the Differentiation of Tumor Cells into Vascular ECs.

Shi S, Zhu C, Hu Y, Jiang P, Zhao J, Xu Q
Frontiers in bioscience (Landmark edition) 2024 Aug 30;29(9):315

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Identification of TAT as a Biomarker Involved in Cell Cycle and DNA Repair in Breast Cancer.

Xie F, Hua S, Guo Y, Wang T, Shan C, Zhang L, He T
Biomolecules 2024 Aug 30;14(9)

---

B cell function in patients with systemic lupus erythematosus is regulated by the upregulation of JunD.

Wu Y, Zhou Y, Zhu Q, Liu Y, Deng D, Zhang J
Heliyon 2024 Aug 30;10(16):e35949

---

Myricetin alleviates renal tubular epithelial-mesenchymal transition via NOX4/NF-κB/snail axis in diabetic nephropathy based on network pharmacology analysis.

Yuan N, Chen Y, Yan Y, Wang F, Xu X, Wang M, Diao J, Xiao W
Heliyon 2024 Aug 30;10(16):e35234

---

Inhibition Effect of STING Agonist SR717 on PRRSV Replication.

Si X, Wang X, Wu H, Yan Z, You L, Liu G, Cai M, Zhang A, Liang J, Yang G, Yao C, Du Y
Viruses 2024 Aug 29;16(9)

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A singular plasmonic-thermoelectric hollow nanostructure inducing apoptosis and cuproptosis for catalytic cancer therapy.

Yang L, Zhao Z, Tian B, Yang M, Dong Y, Zhou B, Gai S, Xie Y, Lin J
Nature communications 2024 Aug 29;15(1):7499

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Identification of the molecular link: STAT3 is a shared key gene linking postmenopausal osteoporosis and sarcopenia.

Liu D, Wang K, Wang J, Cao F, Tao L
Bone & joint research 2024 Aug 28;13(8):411-426

---

Lonidamine Increases the Cytotoxic Effect of 1-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-3-(2-chloroethyl)-3-nitrosourea via Energy Inhibition, Disrupting Redox Homeostasis, and Downregulating MGMT Expression in Human Lung Cancer Cell Line.

Fan T, Shen L, Huang Y, Wang X, Zhao L, Zhong R, Wang P, Sun G
ACS omega 2024 Aug 27;9(34):36134-36147

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Nuclear HMGB1 is critical for CD8 T cell IFN-γ production and anti-tumor immunity.

Xu Z, Ma W, Wang J, Chen H, Li H, Yin Z, Hao J, Chen K
Cell reports 2024 Aug 27;43(8):114591

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A pro-metastatic tRNA fragment drives aldolase A oligomerization to enhance aerobic glycolysis in lung adenocarcinoma.

Wang Q, Song X, Zhang Y, Liang S, Zhang M, Wang H, Feng Y, Li R, Ding H, Chen Y, Xia W, Dong G, Xu L, Mao Q, Jiang F
Cell reports 2024 Aug 27;43(8):114550

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Regulatory effect of β-glucan secreted by Rhizobium pusense on triglyceride metabolism and their relationships with the modulation of intestinal microbiota in mice fed a high-fat diet.

Zhang B, Zhao W, Song D, Lyu X
Food & function 2024 Aug 27;15(17):8759-8774

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A high-fat diet induced depression-like phenotype via hypocretin-HCRTR1 mediated inflammation activation.

Dong J, Zhang J, Cheng S, Qin B, Jin K, Chen B, Zhang Y, Lu J
Food & function 2024 Aug 27;15(17):8661-8673

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NOX1-mediated oxidative stress induces chondrocyte ferroptosis by inhibiting the Nrf2/HO-1 pathway.

Tao L, Yang K, Wang K, Yang Y
Scientific reports 2024 Aug 27;14(1):19877

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Recharacterization of RSL3 reveals that the selenoproteome is a druggable target in colorectal cancer.

DeAngelo SL, Zhao L, Dziechciarz S, Shin M, Solanki S, Balia A, El-Derany MO, Castillo C, Qin Y, Das NK, Bell HN, Paulo JA, Zhang Y, Rossiter NJ, McCulla EC, He J, Talukder I, Ng BW, Schafer ZT, Neamati N, Mancias JD, Koutmos M, Shah YM
bioRxiv : the preprint server for biology 2024 Aug 27;

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SUMO3 inhibition by butyric acid suppresses cell viability and glycolysis and promotes gemcitabine antitumor activity in pancreatic cancer.

Zhu L, Chen G, Huang C, Gao H, Wang Y, Shen Y
Biology direct 2024 Aug 26;19(1):74

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TREM2-dependent activation of microglial cell protects photoreceptor cell during retinal degeneration via PPARγ and CD36.

Zhou W, He J, Shen G, Liu Y, Zhao P, Li J
Cell death & disease 2024 Aug 26;15(8):623

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Tert promotes cardiac regenerative repair after MI through alleviating ROS-induced DNA damage response in cardiomyocyte.

Wei X, Zhou Y, Shao E, Shi X, Han Y, Zhang Y, Wei G, Zheng H, Huang S, Chen Y, Sun J, Liao Y, Liao W, Wang Y, Bin J, Li X
Cell death discovery 2024 Aug 26;10(1):381

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Nicotinamide riboside ameliorates survival time and motor dysfunction in an MPTP-Induced Parkinson's disease zebrafish model through effects on glucose metabolism and endoplasmic reticulum stress.

Luo Q, Yang Y, Xian C, Zhou P, Zhang H, Lv Z, Liu J
Chemico-biological interactions 2024 Aug 25;399:111118

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H3K9me3 Levels Affect the Proliferation of Bovine Spermatogonial Stem Cells.

Yang R, Zhang B, Wang Y, Zhang Y, Zhao Y, Jiang D, Chen L, Tang B, Zhang X
International journal of molecular sciences 2024 Aug 25;25(17)

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Combining Multiple Omics with Molecular Dynamics Reveals SCP2-Mediated Cytotoxicity Effects of Aflatoxin B1 in SW480 Cells.

Chen M, Wen J, Qiu Y, Gao X, Zhang J, Lin Y, Wu Z, Lin X, Zhu A
Toxins 2024 Aug 24;16(9)

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LAT1 expression in colorectal cancer cells is unresponsive to HIF-1/2α accumulation under experimental hypoxia.

Ohgaki R, Hirase Y, Xu M, Okanishi H, Kanai Y
Scientific reports 2024 Aug 23;14(1):19635

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Mutant huntingtin impairs neurodevelopment in human brain organoids through CHCHD2-mediated neurometabolic failure.

Lisowski P, Lickfett S, Rybak-Wolf A, Menacho C, Le S, Pentimalli TM, Notopoulou S, Dykstra W, Oehler D, López-Calcerrada S, Mlody B, Otto M, Wu H, Richter Y, Roth P, Anand R, Kulka LAM, Meierhofer D, Glazar P, Legnini I, Telugu NS, Hahn T, Neuendorf N, Miller DC, Böddrich A, Polzin A, Mayatepek E, Diecke S, Olzscha H, Kirstein J, Ugalde C, Petrakis S, Cambridge S, Rajewsky N, Kühn R, Wanker EE, Priller J, Metzger JJ, Prigione A
Nature communications 2024 Aug 22;15(1):7027

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The different paradigms of NK cell death in patients with severe trauma.

Chang TD, Chen D, Luo JL, Wang YM, Zhang C, Chen SY, Lin ZQ, Zhang PD, Tang TX, Li H, Dong LM, Wu N, Tang ZH
Cell death & disease 2024 Aug 21;15(8):606

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Biallelic variants in DAP3 result in reduced assembly of the mitoribosomal small subunit with altered intrinsic and extrinsic apoptosis and a Perrault syndrome-spectrum phenotype.

Smith TB, Kopajtich R, Demain LAM, Rea A, Thomas HB, Schiff M, Beetz C, Joss S, Conway GS, Shukla A, Yeole M, Radhakrishnan P, Azzouz H, Ben Chehida A, Elmaleh-Bergès M, Glasgow RIC, Thompson K, Oláhová M, He L, Jenkinson EM, Jahic A, Belyantseva IA, Barzik M, Urquhart JE, O' Sullivan J, Williams SG, Bhaskar SS, Carrera S, Blakes AJM, Banka S, Yue WW, Ellingford JM, Houlden H, DDD Study, Munro KJ, Friedman TB, Taylor RW, Prokisch H, O'Keefe RT, Newman WG
medRxiv : the preprint server for health sciences 2024 Aug 21;

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Screening of NSAIDs library identifies Tinoridine as a novel ferroptosis inhibitor for potential intervertebral disc degeneration therapy.

Yang S, Zhu Y, Shi Y, Su S, Liang H, Li S, Wu Z, Miao J, Chen Y, Zhang X, Wang X
Free radical biology & medicine 2024 Aug 20;221:245-256

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Neural epidermal growth factor-like 1 protein (Nell-1) alleviates periodontal tissue destruction in periodontitis by regulating the ratio of M2/M1 macrophage phenotypes.

Ni C, Liao W, Nie H, Ge R, Liu R, Zou X, Yuan Z, Yan F
International immunopharmacology 2024 Aug 20;137:112522

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A novel oral TLR7 agonist orchestrates immune response and synergizes with PD-L1 blockade via type I IFN pathway in lung cancer.

Zuo X, Cheng Q, Wang Z, Liu J, Lu W, Wu G, Zhu S, Liu X, Lv T, Song Y
International immunopharmacology 2024 Aug 20;137:112478

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Cannabidiol alleviates suture-induced corneal pathological angiogenesis and inflammation by inducing myeloid-derived suppressor cells.

Wei C, Mi Y, Sun L, Luo J, Zhang J, Gao Y, Yu X, Ge H, Liu P
International immunopharmacology 2024 Aug 20;137:112429

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Azithromycin regulates Mettl3-mediated NF-κB pathway to enhance M2 polarization of RAW264.7 macrophages and attenuate LPS-triggered cytotoxicity of MLE-12 alveolar cells.

Xu S, Xing J, Zheng L, Su H, Zou Y, Niu Y, Di H
International immunopharmacology 2024 Aug 20;137:112426

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Anti-TL1A monoclonal antibody modulates the dysregulation of Th1/Th17 cells and attenuates granuloma formation in sarcoidosis by inhibiting the PI3K/AKT signaling pathway.

Ma C, Huang J, Zheng Y, Na Y, Wei J, Shan J, Meng K, Zhang X, Zhang S, Wen Y, Ding J
International immunopharmacology 2024 Aug 20;137:112360

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Postsynaptic lncRNA Sera/Pkm2 pathway orchestrates the transition from social competition to rank by remodeling the neural ensemble in mPFC.

Zhu LS, Lai C, Zhou CW, Chen HY, Liu ZQ, Guo Z, Man H, Du HY, Lu Y, Hu F, Chen Z, Shu K, Zhu LQ, Liu D
Cell discovery 2024 Aug 20;10(1):87

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Extract of Phyllanthus emblica L. fruit stimulates basal glucose uptake and ameliorates palmitate-induced insulin resistance through AMPK activation in C2C12 myotubes.

Li HY, Li CF, Liu CH, Chen SC, Liu YF, Lv QH, Zhang W
BMC complementary medicine and therapies 2024 Aug 2;24(1):296

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Inhibition of ANGPTL8 protects against diabetes-associated cognitive dysfunction by reducing synaptic loss via the PirB signaling pathway.

Meng X, Li D, Kan R, Xiang Y, Pan L, Guo Y, Yu P, Luo P, Zou H, Huang L, Zhu Y, Mao B, He Y, Xie L, Xu J, Liu X, Li W, Chen Y, Zhu S, Yang Y, Yu X
Journal of neuroinflammation 2024 Aug 2;21(1):192

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CREB-regulated transcription during glycogen synthesis in astrocytes.

Lim WL, Gaunt JR, Tan JM, Zainolabidin N, Bansal VA, Lye YM, Ch'ng TH
Scientific reports 2024 Aug 2;14(1):17942

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PGC-1α agonism induces fetal hemoglobin and exerts antisickling effects in sickle cell disease.

Sun Y, Benmhammed H, Al Abdullatif S, Habara A, Fu E, Brady J, Williams C, Ilinski A, Sharma A, Mahdaviani K, Alekseyev YO, Campbell JD, Steinberg MH, Cui S
Science advances 2024 Aug 2;10(31):eadn8750

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SLC30A9: an evolutionarily conserved mitochondrial zinc transporter essential for mammalian early embryonic development.

Ge J, Li H, Liang X, Zhou B
Cellular and molecular life sciences : CMLS 2024 Aug 19;81(1):357

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GDNF's Role in Mitigating Intestinal Reactive Gliosis and Inflammation to Improve Constipation and Depressive Behavior in Rats with Parkinson's disease.

Xiaoling Q, Yurong G, Ke X, Yuxiang Q, Panpan A, Yinzhen D, Xue L, Tingting L, Chuanxi T
Journal of molecular neuroscience : MN 2024 Aug 19;74(3):78

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Ac-HSP20 regulates autophagy and promotes the encystation of Acanthamoeba castellanii by inhibiting the PI3K/AKT/mTOR signaling pathway.

Guo S, Liu D, Wan X, Guo D, Zheng M, Zheng W, Feng X
Parasites & vectors 2024 Aug 19;17(1):347

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IFI-16 inhibition attenuates myocardial remodeling following myocardial infarction.

Deng Y, Pang X, Chen L, Peng W, Huang X, Huang P, Zhao S, Li Z, Cai X, Huang Q, Zeng J, Feng Y, Chen B
iScience 2024 Aug 16;27(8):110568

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Targeted dephosphorylation of TFEB promotes its nuclear translocation.

Zhao JF, Shpiro N, Sathe G, Brewer A, Macartney TJ, Wood NT, Negoita F, Sakamoto K, Sapkota GP
iScience 2024 Aug 16;27(8):110432

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Bombinin-BO1 induces hepatocellular carcinoma cell-cycle arrest and apoptosis via the HSP90A-Cdc37-CDK1 axis.

Wang X, Tang P, Gong Y, Yao H, Liang M, Qu H, Han X, Zheng Q, Shi Z, Li D, Jiang Q
iScience 2024 Aug 16;27(8):110382

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Hyperglycemia induced cathepsin L maturation linked to diabetic comorbidities and COVID-19 mortality.

He Q, Zhao MM, Li MJ, Li XY, Jin JM, Feng YM, Zhang L, Huang WJ, Yang F, Yang JK
eLife 2024 Aug 16;13

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Diosgenin attenuates nonalcoholic hepatic steatosis through the hepatic SIRT1/PGC-1α pathway.

Meng D, Yin G, Chen S, Zhang X, Yu W, Wang L, Liu H, Jiang W, Sun Y, Zhang F
European journal of pharmacology 2024 Aug 15;977:176737

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Branched-chain amino acid transaminase 1 confers EGFR-TKI resistance through epigenetic glycolytic activation.

Zhang T, Pan Z, Gao J, Wu Q, Bai G, Li Y, Tong L, Feng F, Lai M, Liu Y, Song P, Ning Y, Tang H, Luo W, Chen Y, Fang Y, Zhang H, Liu Q, Zhang Y, Wang H, Chen Z, Chen Y, Geng M, Ji H, Zhao G, Zhou H, Ding J, Xie H
Signal transduction and targeted therapy 2024 Aug 15;9(1):216

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2,3-Diphosphoglyceric Acid Alleviating Hypoxic-Ischemic Brain Damage through p38 MAPK Modulation.

Ni J, Zhao J, Chen H, Liu W, Le M, Guo X, Dong X
International journal of molecular sciences 2024 Aug 15;25(16)

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Role and Regulatory Mechanism of circRNA_14820 in the Proliferation and Differentiation of Goat Skeletal Muscle Satellite Cells.

Yang P, Li X, Liu C, Han Y, E G, Huang Y
International journal of molecular sciences 2024 Aug 15;25(16)

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Nrf2 expression, mitochondrial fission, and neuronal apoptosis in the prefrontal cortex of methamphetamine abusers and rats.

Nie QY, Yang GM, Zhang P, Dong WJ, Jing D, Hou ZP, Peng YX, Yu Y, Li LH, Hong SJ
Brain research 2024 Aug 15;1837:148973

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Intestinal glucagon-like peptide-1: A new player associated with impaired counterregulatory responses to hypoglycaemia in type 1 diabetic mice.

Jin FX, Wang Y, Li MN, Li RJ, Guo JT
World journal of diabetes 2024 Aug 15;15(8):1764-1777

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MZT2A serves as a prognostic biomarker and promotes the progression of kidney renal clear cell carcinoma.

Cao L, Jing X, Liu L, Wang H, Zhu J, Zhou J, Peng H, Zhang J, Li F, Wang X, Zhao L
Heliyon 2024 Aug 15;10(15):e35695

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Single-cell sequencing analysis revealed that WDR72 was a novel cancer stem cells related gene in gastric cancer.

Zheng L, Lu J, Kong D, Zhan Y
Heliyon 2024 Aug 15;10(15):e35549

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Pan-cancer investigation of RFX family and associated genes identifies RFX8 as a therapeutic target in leukemia.

Cui Z, Fu Y, Zhou M, Feng H, Zhang L, Ma S, Chen C
Heliyon 2024 Aug 15;10(15):e35368

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Multimodal mechanisms of pathogenic variants in the signal peptide of FIX leading to hemophilia B.

Gao M, Chen L, Yang J, Dong S, Cao Q, Cui Z, Dong Y, Liu H, Shen Y, Yang H, Hao Z, Zhang L, Li W, Tie JK, Shen G
Blood advances 2024 Aug 13;8(15):3893-3905

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Single-cell analysis identified PDIA3 as regulator of malignant characteristics and macrophage function in human cancers.

Wu W, Peng G, Wang K, Yang Y, Liu Z, Xiao G
Functional & integrative genomics 2024 Aug 13;24(4):136

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The role of BUD31 in clear cell renal cell carcinoma: prognostic significance, alternative splicing, and tumor immune environment.

Wu X, Fan R, Zhang Y, Duan C, Yao X, Liu K, Lin D, Chen Z
Clinical and experimental medicine 2024 Aug 13;24(1):191

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Biomineralization-Tuned Nanounits Reprogram the Signal Transducer and Activator of Transcription 3 Signaling for Ferroptosis-Immunotherapy in Cancer Stem Cells.

Zhao Y, Fei Y, Zhao Y, Li M, Hu Y, Cai K, Yu SH, Luo Z
ACS nano 2024 Aug 13;18(32):21268-21287

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Mitochondria-Targeted Multifunctional Nanoprodrugs by Inhibiting Metabolic Reprogramming for Combating Cisplatin-Resistant Lung Cancer.

Lu H, Tong W, Jiang M, Liu H, Meng C, Wang K, Mu X
ACS nano 2024 Aug 13;18(32):21156-21170

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Exploring the clinical and biological significance of the cell cycle-related gene CHMP4C in prostate cancer.

Xiao X, Li Z, Li Q, Qing L, Wang Y, Ye F, Dong Y, Di X, Mi J
BMC medical genomics 2024 Aug 13;17(1):210

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Dihydrolipoamide dehydrogenase (DLD) is a novel molecular target of bortezomib.

Feng Y, Luo H, Huang J, Zhang Y, Wen J, Li L, Mi Z, Gao Q, He S, Liu X, Zhai X, Wang X, Zhang L, Niu T, Zheng Y
Cell death & disease 2024 Aug 13;15(8):588

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Hippo signaling pathway regulates Ebola virus transcription and egress.

Liang J, Djurkovic MA, Leavitt CG, Shtanko O, Harty RN
Nature communications 2024 Aug 13;15(1):6953

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Exosomes derived from BMSCs in osteogenic differentiation promote type H blood vessel angiogenesis through miR-150-5p mediated metabolic reprogramming of endothelial cells.

Wu F, Song C, Zhen G, Jin Q, Li W, Liang X, Xu W, Guo W, Yang Y, Dong W, Jiang A, Kong P, Yan J
Cellular and molecular life sciences : CMLS 2024 Aug 12;81(1):344

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KAT6A/YAP/TEAD4 pathway modulates osteoclastogenesis by regulating the RANKL/OPG ratio on the compression side during orthodontic tooth movement.

Tan K, Wang J, Su X, Zheng Y, Li W
Progress in orthodontics 2024 Aug 12;25(1):29

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Fe(3)O(4)@R837 Nanoplatform Enhances Chemical Dynamic Therapy and Immunotherapy: Integrated Transcriptomic Analysis Reveals Key Genes in Breast Cancer Prognosis.

Zhang S, Liu Y, Xie Y, Ding C, Zuo R, Guo Z, Qi S, Fu T, Chen W
ACS biomaterials science & engineering 2024 Aug 12;10(8):5274-5289

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Crizotinib and its enantiomer suppress ferroptosis by decreasing PE-O-PUFA content.

Cen SY, Lin F, Li X, Hu Y, Liu JP, Xue Z, Gao Y, Sun YP, Zhu S, Dang Y, Zhao Y, Yuan HX
Cell death discovery 2024 Aug 12;10(1):360

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The mechanism of extracellular CypB promotes glioblastoma adaptation to glutamine deprivation microenvironment.

Yin H, Liu Y, Dong Q, Wang H, Yan Y, Wang X, Wan X, Yuan G, Pan Y
Cancer letters 2024 Aug 10;597:216862

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Network pharmacology-based research into the mechanism of ferulic acid on acute lung injury through enhancing transepithelial sodium transport.

Zhai Y, Yu T, Xin S, Ding Y, Cui Y, Nie H
Journal of ethnopharmacology 2024 Aug 10;330:118230

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The receptor VLDLR binds Eastern Equine Encephalitis virus through multiple distinct modes.

Cao D, Ma B, Cao Z, Xu X, Zhang X, Xiang Y
Nature communications 2024 Aug 10;15(1):6866

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Optimized inhaled LNP formulation for enhanced treatment of idiopathic pulmonary fibrosis via mRNA-mediated antibody therapy.

Bai X, Chen Q, Li F, Teng Y, Tang M, Huang J, Xu X, Zhang XQ
Nature communications 2024 Aug 10;15(1):6844

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METTL3 Promotes Nucleus Pulposus Cell Senescence in Intervertebral Disc Degeneration by Regulating TLR2 m6A Methylation and Gut Microbiota.

Ni S, Huang X, Li X, Shi C, Fan M, Zhao L, Rong Z, Zhang H
The journals of gerontology. Series A, Biological sciences and medical sciences 2024 Aug 1;79(8)

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Tumor Vessel Normalization via PFKFB3 Inhibition Alleviates Hypoxia and Increases Tumor Necrosis in Rectal Cancer upon Radiotherapy.

Edelmann M, Fan S, De Oliveira T, Goldhardt T, Sartorius D, Midelashvili T, Conrads K, Paul NB, Beißbarth T, Fleischer JR, Blume ML, Bohnenberger H, Josipovic N, Papantonis A, Linnebacher M, Dröge LH, Ghadimi M, Rieken S, Conradi LC
Cancer research communications 2024 Aug 1;4(8):2008-2024

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Fusobacterium nucleatum induces oxaliplatin resistance by inhibiting ferroptosis through E-cadherin/β-catenin/GPX4 axis in colorectal cancer.

Li B, Wei Z, Wang Z, Xu F, Yang J, Lin B, Chen Y, Wenren H, Wu L, Guo X, Liu Y, Wei Y
Free radical biology & medicine 2024 Aug 1;220:125-138

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The oncogenic kinase TOPK upregulates in psoriatic keratinocytes and contributes to psoriasis progression by regulating neutrophils infiltration.

Zeng F, Du S, Wu M, Dai C, Li J, Wang J, Hu G, Cai P, Wang L
Cell communication and signaling : CCS 2024 Aug 1;22(1):386

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Neuritin promotes autophagic flux by inhibiting the cGAS-STING pathway to alleviate brain injury after subarachnoid haemorrhage.

Zhang H, Ren K, Hu Y, Liu B, He Y, Xu H, Ma K, Tian W, Dai L, Zhao D
Brain research 2024 Aug 1;1836:148909

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P2Y1R silencing in Astrocytes Protected Neuroinflammation and Cognitive Decline in a Mouse Model of Alzheimer's Disease.

Luo S, Tamada A, Saikawa Y, Wang Y, Yu Q, Hisatsune T
Aging and disease 2024 Aug 1;15(4):1969-1988

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Schizophrenia-Like Behaviors Arising from Dysregulated Proline Metabolism Are Associated with Altered Neuronal Morphology and Function in Mice with Hippocampal PRODH Deficiency.

Yao Y, Jin C, Liao Y, Huang X, Wei Z, Zhang Y, Li D, Su H, Han W, Qin D
Aging and disease 2024 Aug 1;15(4):1952-1968

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Altered vacuole membrane protein 1 (VMP1) expression is associated with increased NLRP3 inflammasome activation and mitochondrial dysfunction.

Zack SR, Venkatesan M, Nikolaienko R, Cook B, Melki R, Zima AV, Campbell EM
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Apr;73(4):563-580

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Calreticulin regulates the expression of MMP14 and ADAR1 through EIF2AK2 signaling to promote the proliferation and progression of malignant melanoma cells.

Liang L, Wang J, Guo T, Huang L, Wu Y, Xu R, Huang T, Ma B
Neoplasma 2024 Apr;71(2):180-192

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Insertion of a neomycin selection cassette in the Amigo1 locus alters gene expression in the olfactory epithelium leading to region-specific defects in olfactory receptor neuron development.

Raja R, Dumontier E, Phen A, Cloutier JF
Genesis (New York, N.Y. : 2000) 2024 Apr;62(2):e23594

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Teriflunomide Promotes Blood-Brain Barrier Integrity by Upregulating Claudin-1 via the Wnt/β-catenin Signaling Pathway in Multiple Sclerosis.

Zhao Y, Chen C, Xiao X, Fang L, Cheng X, Chang Y, Peng F, Wang J, Shen S, Wu S, Huang Y, Cai W, Zhou L, Qiu W
Molecular neurobiology 2024 Apr;61(4):1936-1952

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ZFP541 and KCTD19 regulate chromatin organization and transcription programs for male meiotic progression.

Zhou X, Fang K, Liu Y, Li W, Tan Y, Zhang J, Yu X, Wang G, Zhang Y, Shang Y, Zhang L, Chen CD, Wang S
Cell proliferation 2024 Apr;57(4):e13567

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Crosstalk between autophagy and inflammasomes in ricin-induced inflammatory injury.

Zhang S, Zhao N, Song S, Wang Y, Wang Y, Sun C, Dong M, Huo M, Xu N, Liu W, Li G
Toxicology and applied pharmacology 2024 Apr;485:116890

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Vinpocetine represses the progression of nonalcoholic steatohepatitis in mice by mediating inflammasome components via NF-κB signaling.

Zhu Y, Tang H, Zhao H, Lu J, Lin K, Ni J, Zhao B, Wu G, Tan C
Gastroenterologia y hepatologia 2024 Apr;47(4):366-376

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Upregulation of UHRF1 Promotes PINK1-mediated Mitophagy to Alleviates Ferroptosis in Diabetic Nephropathy.

Ji H, Zhao Y, Ma X, Wu L, Guo F, Huang F, Song Y, Wang J, Qin G
Inflammation 2024 Apr;47(2):718-732

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Britannin as a novel NLRP3 inhibitor, suppresses inflammasome activation in macrophages and alleviates NLRP3-related diseases in mice.

Shao JJ, Li WF, Sun JF, Zhuang ZS, Min JL, Long XH, Wu GJ, Xu HW, Liang G
Acta pharmacologica Sinica 2024 Apr;45(4):803-814

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Mechanisms of Dangua Fang in multi-target and multi-method regulation of glycolipid metabolism based on phosphoproteomics.

Xianpei H, Zhita W, Liang LI, Liuqing Y, Suping H, Lang J, Weidong HE
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2024 Apr;44(2):334-344

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Propofol-induced LINC01133 inhibits the progression of colorectal cancer via miR-186-5p/NR3C2 axis.

Yao Y, Zhang F, Liu F, Xia D
Environmental toxicology 2024 Apr;39(4):2265-2284

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Polystyrene microplastics mediate cell cycle arrest, apoptosis, and autophagy in the G2/M phase through ROS in grass carp kidney cells.

Lu H, Hou L, Zhang Y, Guo T, Wang Y, Xing M
Environmental toxicology 2024 Apr;39(4):1923-1935

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Efficient gene delivery by multifunctional star poly (β-amino ester)s into difficult-to-transfect macrophages for M1 polarization.

Bo T, Wang C, Yao D, Jiang Q, Zhao Y, Wang F, He W, Xu W, Zhou H, Li M, Zhang S, Xue R
Journal of controlled release : official journal of the Controlled Release Society 2024 Apr;368:157-169

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Lysosomal destabilization: A missing link between pathological calcification and osteoarthritis.

Ye T, Wang C, Yan J, Qin Z, Qin W, Ma Y, Wan Q, Lu W, Zhang M, Tay FR, Jiao K, Niu L
Bioactive materials 2024 Apr;34:37-50

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Construction of a versatile fusion protein for targeted therapy and immunotherapy.

Huang XS, Yang LT, Yang K, Zhou H, Abudureheman T, Zheng WW, Chen KM, Duan CW
Protein science : a publication of the Protein Society 2024 Apr;33(4):e4944

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Novel α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor (AMPAR) potentiator LT-102: A promising therapeutic agent for treating cognitive impairment associated with schizophrenia.

Qi X, Yu X, Wei L, Jiang H, Dong J, Li H, Wei Y, Zhao L, Deng W, Guo W, Hu X, Li T
CNS neuroscience & therapeutics 2024 Apr;30(4):e14713

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Integrated transcriptomic and proteomic profiling reveals the key molecular signatures of brain endothelial reperfusion injury.

Ji Y, Chen Y, Tan X, Huang X, Gao Q, Ma Y, Yang S, Yin M, Yu M, Fang C, Wang Y, Shi Z, Chang J
CNS neuroscience & therapeutics 2024 Apr;30(4):e14483

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Isorhamnetin Downregulates MMP2 and MMP9 to Inhibit Development of Rheumatoid Arthritis through SRC/ERK/CREB Pathway.

Liu XR, Li SF, Mei WY, Liu XD, Zhou RB
Chinese journal of integrative medicine 2024 Apr;30(4):299-310

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Oxidative stress-induced changes in the transcriptomic profile of extracellular vesicles.

Dellar ER, Hill C, Carter DRF, Baena-Lopez LA
Journal of extracellular biology 2024 Apr;3(4):e150

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Abnormal activation of RFC3, A YAP1/TEAD downstream target, promotes gastric cancer progression.

Guo Z, Guo L
International journal of clinical oncology 2024 Apr;29(4):442-455

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Cathepsin L prevents the accumulation of alpha-synuclein fibrils in the cell.

Matsuki A, Watanabe Y, Hashimoto S, Hoshino A, Matoba S
Genes to cells : devoted to molecular & cellular mechanisms 2024 Apr;29(4):328-336

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Investigation of GPR143 as a promising novel marker for the progression of skin cutaneous melanoma through bioinformatic analyses and cell experiments.

Bai R, Yin P, Xing Z, Wu S, Zhang W, Ma X, Gan X, Liang Y, Zang Q, Lei H, Wei Y, Zhang C, Dai B, Zheng Y
Apoptosis : an international journal on programmed cell death 2024 Apr;29(3-4):372-392

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HBI-8000 improves heart failure with preserved ejection fraction via the TGF-β1/MAPK signalling pathway.

Tian J, Li W, Zeng L, Li Y, Du J, Li Y, Li B, Su G
Journal of cellular and molecular medicine 2024 Apr;28(7):e18238

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Retinoic acid induced specific changes in the phosphoproteome of C17.2 neural stem cells.

Zhang C, Ge L, Xie H, Liu X, Xun C, Chen Y, Chen H, Lu M, Chen P
Journal of cellular and molecular medicine 2024 Apr;28(7):e18205

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Lipin-1 deficiency deteriorates defect of fatty acid β-oxidation and lipid-related kidney damage in diabetic kidney disease.

Lin S, Wang L, Jia Y, Sun Y, Qiao P, Quan Y, Liu J, Hu H, Yang B, Zhou H
Translational research : the journal of laboratory and clinical medicine 2024 Apr;266:1-15

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Polyvinyl alcohol/carboxymethyl chitosan-based hydrogels loaded with taxifolin liposomes promote diabetic wound healing by inhibiting inflammation and regulating autophagy.

Ding Q, Liu X, Liu X, Chai G, Wang N, Ma S, Zhang L, Zhang S, Yang J, Wang Y, Shen L, Ding C, Liu W
International journal of biological macromolecules 2024 Apr;263(Pt 1):130226

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A Pt(II) complex bearing N-heterocycle ring induced ferroptotic cell death in ovarian cancer.

Shen X, Peng Y, Zhou H, Ye X, Han Z, Shi X
Journal of inorganic biochemistry 2024 Apr;253:112502

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Excessive processing and acetylation of OPA1 aggravate age-related hearing loss via the dysregulation of mitochondrial dynamics.

Zhang A, Pan Y, Wang H, Ding R, Zou T, Guo D, Shen Y, Ji P, Huang W, Wen Q, Wang Q, Hu H, Wu J, Xiang M, Ye B
Aging cell 2024 Apr;23(4):e14091

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The NLRX1-SLC39A7 complex orchestrates mitochondrial dynamics and mitophagy to rejuvenate intervertebral disc by modulating mitochondrial Zn(2+) trafficking.

Song Y, Liang H, Li G, Ma L, Zhu D, Zhang W, Tong B, Li S, Gao Y, Wu X, Zhang Y, Feng X, Wang K, Yang C
Autophagy 2024 Apr;20(4):809-829

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Overexpression of YTHDF3 increases the specific productivity of the recombinant protein in CHO cells by promoting the translation process.

Cui ZM, Feng YY, Gao YP, Wang HT, Lu JT, Guo JL, Xu HY, Qiu LL, Wang TY, Jia YL
Biotechnology journal 2024 Apr;19(4):e2400078

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DDIT3/CHOP promotes LPS/ATP-induced pyroptosis in osteoblasts via mitophagy inhibition.

Dong Z, Yang B, Jia M, Yang C, Wang S, Mu H, Wang J
Biochimica et biophysica acta. Molecular cell research 2024 Apr;1871(4):119712

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The regulatory role of the apelin/APJ axis in scarring: Identification of upstream and downstream mechanisms.

Shi N, Wang Y, Xia Z, Zhang J, Jia S, Jiao Y, Wang C, Wang X, Zhao J, Zhang J, Jiang D
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167125

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Discovery of 2,8-dihydroxyadenine in HUA patients with uroliths and biomarkers for its associated nephropathy.

Zheng X, Lu X, Li Q, Gong S, Chen B, Xie Q, Yan F, Li J, Su Z, Liu Y, Guo Z, Chen J, Li Y
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167051

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LCP1-mediated cytoskeleton alterations involve in arsenite-triggered malignant phenotype of human immortalized prostate stromal cells.

Yang Y, Zhou M, Huang Y, Ye X, Mo Y, Huang Y, Wang S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114548

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Development of a therapeutic monoclonal antibody against circulating adipocyte fatty acid binding protein to treat ischaemic stroke.

Liao B, Yang S, Geng L, Zong J, Zhang Z, Jiang M, Jiang X, Li S, Xu A, Chang J, Hoo RLC
British journal of pharmacology 2024 Apr;181(8):1238-1255

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Trilobatin attenuates cerebral ischaemia/reperfusion-induced blood-brain barrier dysfunction by targeting matrix metalloproteinase 9: The legend of a food additive.

Feng L, Li Y, Lin M, Xie D, Luo Y, Zhang Y, He Z, Gong Q, Zhun ZY, Gao J
British journal of pharmacology 2024 Apr;181(7):1005-1027

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Chidamide improves gefitinib treatment outcomes in NSCLC by attenuating recruitment and immunosuppressive function of myeloid-derived suppressor cells.

Shao J, Ye Z, Shen Z, Liu N, Zhang L, Tachibana M, Xie Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Apr;173:116306

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Iron overload increases the sensitivity of endometriosis stromal cells to ferroptosis via a PRC2-independent function of EZH2.

Luo Y, Li L, Hu Q, Zhang Z, Liu F, Peng Y, Zou Y, Chen L
The international journal of biochemistry & cell biology 2024 Apr;169:106553

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Design, synthesis, and biological evaluation of gambogenic acid derivatives: Unraveling their anti-cancer effects by inducing pyroptosis.

Huang Q, Guo K, Ren Y, Tan J, Ren Y, Zhang L, Zheng C, Xu H
Bioorganic chemistry 2024 Apr;145:107182

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NF-κB affected the serum levels of TNF-α and IL-1β via activation of the MAPK/NF-κB signaling pathway in rat model of acute pulmonary microthromboembolism.

Zhong Y, Liang B, Zhang X, Li J, Zeng D, Huang T, Wu J
Pulmonary circulation 2024 Apr;14(2):e12357

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Nanointegrative Glycoengineering-Activated Necroptosis of Triple Negative Breast Cancer Stem Cells Enables Self-Amplifiable Immunotherapy for Systemic Tumor Rejection.

Zhao Y, Li Y, He J, Li M, Yao X, Yang H, Luo Z, Luo P, Su M
Advanced healthcare materials 2024 Apr;13(9):e2303337

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Xanthohumol ameliorates drug-induced hepatic ferroptosis via activating Nrf2/xCT/GPX4 signaling pathway.

Deng Y, Chu X, Li Q, Zhu G, Hu J, Sun J, Zeng H, Huang J, Ge G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155458

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Preparation and characterisation of baicalin magnesium and its protective effect in ulcerative colitis via gut microbiota-bile acid axis modulation.

Zhang L, Miao C, Wang Z, Guan X, Ma Y, Song J, Shen S, Song H, Li M, Liu C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155416

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Tiliroside attenuates acute kidney injury by inhibiting ferroptosis through the disruption of NRF2-KEAP1 interaction.

Cai F, Li D, Zhou K, Zhang W, Yang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155407

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Cadmium disrupts spermatogenic cell cycle via piRNA-DQ717867/p53 pathway.

Wei J, Dai J, Shi X, Zhao R, Fu G, Li R, Xia C, Zhang L, Zhou T, Wang H, Shi Y
Reproductive toxicology (Elmsford, N.Y.) 2024 Apr;125:108554

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Histone deacetylase 6 suppression of renal tubular epithelial cell promotes interstitial mineral deposition via alpha-tubulin acetylation.

Li S, Wu W, Yang B, Liu Z, Duan X, Sun X, Liu H, Zhang S, Zhou Y, Wu W
Cellular signalling 2024 Apr;116:111057

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Beta-Cell Tipe1 Orchestrates Insulin Secretion and Cell Proliferation by Promoting Gαs/cAMP Signaling via USP5.

Ding L, Sun Y, Liang Y, Zhang J, Fu Z, Ren C, Li P, Liu W, Xiao R, Wang H, Zhang Z, Yue X, Li C, Wu Z, Feng Y, Liang X, Ma C, Gao L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(16):e2304940

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Baicalin inhibits monosodium urate crystal-induced pyroptosis in renal tubular epithelial cell line through Panx-1/P2X7 pathways: Molecular docking, molecular dynamics, and in vitro experiments.

Fu W, Liu Z, Wang Y, Li X, Yu X, Li Y, Yu Z, Qiu Y, Mei Z, Xu L
Chemical biology & drug design 2024 Apr;103(4):e14522

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PPARγ alleviates preeclampsia development by regulating lipid metabolism and ferroptosis.

Lai W, Yu L, Deng Y
Communications biology 2024 Apr 9;7(1):429

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Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8(+) T cell effector functions.

Cong J, Liu P, Han Z, Ying W, Li C, Yang Y, Wang S, Yang J, Cao F, Shen J, Zeng Y, Bai Y, Zhou C, Ye L, Zhou R, Guo C, Cang C, Kasper DL, Song X, Dai L, Sun L, Pan W, Zhu S
Immunity 2024 Apr 9;57(4):876-889.e11

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Occludin and collagen IV degradation mediated by the T9SS effector SspA contributes to blood-brain barrier damage in ducks during Riemerella anatipestifer infection.

Chen Z, Zhu M, Liu D, Wu M, Niu P, Yu Y, Ding C, Yu S
Veterinary research 2024 Apr 9;55(1):49

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Hesperidin ameliorates H(2)O(2)-induced bovine mammary epithelial cell oxidative stress via the Nrf2 signaling pathway.

Huang Q, Liu J, Peng C, Han X, Tan Z
Journal of animal science and biotechnology 2024 Apr 9;15(1):57

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LDL receptor-related protein 5 selectively transports unesterified polyunsaturated fatty acids to intracellular compartments.

Tang W, Luan Y, Yuan Q, Li A, Chen S, Menacherry S, Young L, Wu D
Nature communications 2024 Apr 9;15(1):3068

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Activation of the IKK2/NF-κB pathway in VSMCs inhibits calcified vascular stiffness in CKD.

Miyazaki-Anzai S, Masuda M, Keenan AL, Shiozaki Y, Miranda JG, Miyazaki M
JCI insight 2024 Apr 8;9(7)

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MiR-574-5p activates human TLR8 to promote autoimmune signaling and lupus.

Wang T, Song D, Li X, Luo Y, Yang D, Liu X, Kong X, Xing Y, Bi S, Zhang Y, Hu T, Zhang Y, Dai S, Shao Z, Chen D, Hou J, Ballestar E, Cai J, Zheng F, Yang JY
Cell communication and signaling : CCS 2024 Apr 8;22(1):220

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NBR1-p62-Nrf2 mediates the anti-pulmonary fibrosis effects of protodioscin.

Zeng Q, Wen BB, Liu X, Luo YY, Hu ZG, Huang L, Zhang XH, Huang XT, Zhou TT, Sang XX, Luo YY, Xiong DY, Luo ZQ, Liu W, Tang SY
Chinese medicine 2024 Apr 8;19(1):60

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ATP Citrate Lyase is a General Tumour Biomarker and Contributes to the Development of Cutaneous Squamous Cell Carcinoma.

Luo R, Huang Y, Bai R, Liu M, Sun L, Wang X, Zheng Y
Acta dermato-venereologica 2024 Apr 8;104:adv23805

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Nur77 Mediates Anaphylaxis by Regulating miR-21a.

Jo H, Jeoung J, Shim K, Jeoung D
Current issues in molecular biology 2024 Apr 6;46(4):3175-3192

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Mulberry (Morus alba L.) leaf water extract attenuates type 2 diabetes mellitus by regulating gut microbiota dysbiosis, lipopolysaccharide elevation and endocannabinoid system disorder.

Du Y, Zhang R, Zheng XX, Zhao YL, Chen YL, Ji S, Guo MZ, Tang DQ
Journal of ethnopharmacology 2024 Apr 6;323:117681

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Jiawei Buzhong Yiqi decoction ameliorates polycystic ovary syndrome via oocyte-granulosa cell communication.

Hu R, Huang Y, Geng Y, Liu Z, Li F, Zhang Z, Ma W, Song K, Dong H, Song Y, Zhang M
Journal of ethnopharmacology 2024 Apr 6;323:117654

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Systematic HOIP interactome profiling reveals critical roles of linear ubiquitination in tissue homeostasis.

Fu Y, Li L, Zhang X, Deng Z, Wu Y, Chen W, Liu Y, He S, Wang J, Xie Y, Tu Z, Lyu Y, Wei Y, Wang S, Cui CP, Liu CH, Zhang L
Nature communications 2024 Apr 6;15(1):2974

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The role of mTORC1/TFEB axis mediated lysosomal biogenesis and autophagy impairment in fluoride neurotoxicity and the intervention effects of resveratrol.

Tang H, Hou H, Song L, Tian Z, Liu W, Xia T, Wang A
Journal of hazardous materials 2024 Apr 5;467:133634

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METTL3-mediated m(6)A methylation of SLC38A1 stimulates cervical cancer growth.

Liu HT, Zhao Y, Wang HC, Liu QL
Biochemical and biophysical research communications 2024 Apr 30;716:150039

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Identification of HK3 as a promising immunomodulatory and prognostic target in sepsis-induced acute lung injury.

Zhu M, Tang X, Xu J, Gong Y
Biochemical and biophysical research communications 2024 Apr 30;706:149759

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Mycobacterium tuberculosis PE_PGRS38 Enhances Intracellular Survival of Mycobacteria by Inhibiting TLR4/NF-κB-Dependent Inflammation and Apoptosis of the Host.

Ullah H, Shi X, Taj A, Cheng L, Yan Q, Sha S, Ahmad, Kang J, Haris M, Ma X, Ma Y
Biology 2024 Apr 30;13(5)

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E2F-mediated POLA2 upregulation is correlated with macrophage infiltration and poor prognosis in hepatocellular carcinoma.

Teng Y, Liu R
Translational cancer research 2024 Apr 30;13(4):1848-1860

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Baicalin reduces inflammation to inhibit lung cancer via targeting SOCS1/NF-κB/STAT3 axis.

Guo L, Yue M, Ma C, Wang Y, Hou J, Li H
Heliyon 2024 Apr 30;10(8):e29361

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Epigenetic regulation of FOXI2 promotes clear cell renal cell carcinoma progression.

Zhou S, Cheng C, Liao YX, Wang L, Zeng JM, Zhou FF, Zhang XQ, Yang T
Heliyon 2024 Apr 30;10(8):e29218

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Phthalates Induce Neurotoxicity by Disrupting the Mfn2-PERK Axis-Mediated Endoplasmic Reticulum-Mitochondria Interaction.

Zhao Y, Chang YH, Ren HR, Lou M, Jiang FW, Wang JX, Chen MS, Liu S, Shi YS, Zhu HM, Li JL
Journal of agricultural and food chemistry 2024 Apr 3;72(13):7411-7422

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Expression of Multicopy Tandem Recombinant Ginseng Hexapeptide in Bacillus subtilis and the Evaluation of Antiaging Activity.

Xiang Q, Qu L, Lei H, Duan Z, Zhu C, Yuwen W, Ma X, Fan D
Journal of agricultural and food chemistry 2024 Apr 3;72(13):7266-7278

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CD63(+) cancer-associated fibroblasts confer CDK4/6 inhibitor resistance to breast cancer cells by exosomal miR-20.

Sun J, Du R, Li X, Liu C, Wang D, He X, Li G, Zhang K, Wang S, Hao Q, Zhang Y, Li M, Gao Y, Zhang C
Cancer letters 2024 Apr 28;588:216747

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Proteomics Identifies LUC7L3 as a Prognostic Biomarker for Hepatocellular Carcinoma.

Hou Y, Wang S, Zhang Y, Huang X, Zhang X, He F, Tian C, Sun A
Current issues in molecular biology 2024 Apr 27;46(5):4004-4020

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Agomirs upregulating carboxypeptidase E expression rescue hippocampal neurogenesis and memory deficits in Alzheimer's disease.

Jiang D, Liu H, Li T, Zhao S, Yang K, Yao F, Zhou B, Feng H, Wang S, Shen J, Tang J, Zhang YX, Wang Y, Guo C, Tang TS
Translational neurodegeneration 2024 Apr 26;13(1):24

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Sphingolipid biosynthesis is essential for metabolic rewiring during T(H)17 cell differentiation.

Abimannan T, Parthibane V, Le SH, Vijaykrishna N, Fox SD, Karim B, Kunduri G, Blankenberg D, Andresson T, Bamba T, Acharya U, Acharya JK
Science advances 2024 Apr 26;10(17):eadk1045

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Expression and functional significance of phosphoenolpyruvate carboxykinase 1 in uveal melanoma.

Bi HE, Zhang J, Yao Y, Wang S, Yao J, Shao Z, Jiang Q
Cell death discovery 2024 Apr 26;10(1):196

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Peptide Inhibitor Targeting the Extraterminal Domain in BRD4 Potently Suppresses Breast Cancer Both In Vitro and In Vivo.

Huang QX, Fan DM, Zheng ZZ, Ran T, Bai A, Xiao RQ, Hu GS, Liu W
Journal of medicinal chemistry 2024 Apr 25;67(8):6658-6672

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Structure-Guided Discovery and Preclinical Assessment of Novel (Thiophen-3-yl)aminopyrimidine Derivatives as Potent ERK1/2 Inhibitors.

Shuai W, Xiao H, Yang P, Zhang Y, Bu F, Wu Y, Sun Q, Wang G, Ouyang L
Journal of medicinal chemistry 2024 Apr 25;67(8):6425-6455

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Pterostilbene nanoemulsion promotes Nrf2 signaling pathway to downregulate oxidative stress for treating Alzheimer's disease.

Liu J, Xu J, Jia L, Zhou Y, Fu Q, Wang Y, Mu D, Wang D, Li N, Hou Y
International journal of pharmaceutics 2024 Apr 25;655:124002

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Abrogation of KLF5 sensitizes BRCA1-proficient pancreatic cancer to PARP inhibition.

Zhang Z, Liu Y, Xu Y, Xu Z, Jia J, Jin Y, Wang W, Liu L
Acta biochimica et biophysica Sinica 2024 Apr 25;56(4):576-585

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Norcantharidin Enhances the Antitumor Effect of 5-Fluorouracil by Inducing Apoptosis of Cervical Cancer Cells: Network Pharmacology, Molecular Docking, and Experimental Validation.

Huang Y, Wan XW, Du YT, Feng Y, Yang LS, Liu YB, Chen T, Zhu Z, Xu YT, Wang CC
Current issues in molecular biology 2024 Apr 25;46(5):3906-3918

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CHOP regulated by METTL14-m6A affects cell cycle arrest and regorafenib sensitivity in HCC cells.

Pan Y, You B, Zhao X, Zhang S, Li W
BMC cancer 2024 Apr 25;24(1):525

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Association of Cadherin-Related Family Member 1 with Traumatic Brain Injury.

Jiang Y, Chen P, Zhao Y, Zhang Y
Cellular and molecular neurobiology 2024 Apr 24;44(1):41

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Anti-hepatocellular carcinoma activity of Sorbaria sorbifolia by regulating VEGFR and c-Met/apoptotic pathway.

Xu ZH, Dang Y, Dong Y, Dong CY, Liu Y, Chen X, Yao Z, Shi JP
Journal of ethnopharmacology 2024 Apr 24;324:117758

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Leech extract alleviates idiopathic pulmonary fibrosis by TGF-β1/Smad3 signaling pathway.

Zhang Y, Lu YB, Zhu WJ, Gong XX, Qian R, Lu YJ, Li Y, Yao WF, Bao BH, Zhang Y, Zhang L, Cheng FF
Journal of ethnopharmacology 2024 Apr 24;324:117737

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Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome.

Wu S, Dai X, Xia Y, Zhao Q, Zhao H, Shi Z, Yin X, Liu X, Zhang A, Yao Z, Zhang H, Li Q, Thorne RF, Zhang S, Sheng W, Hu W, Gu H
Cell reports 2024 Apr 23;43(4):114111

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Genetic or pharmacologic blockade of mPGES-2 attenuates renal lipotoxicity and diabetic kidney disease by targeting Rev-Erbα/FABP5 signaling.

Zhong D, Chen J, Qiao R, Song C, Hao C, Zou Y, Bai M, Su W, Yang B, Sun D, Jia Z, Sun Y
Cell reports 2024 Apr 23;43(4):114075

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Hippo-signaling-controlled MHC class I antigen processing and presentation pathway potentiates antitumor immunity.

Peng L, Zhou L, Li H, Zhang X, Li S, Wang K, Yang M, Ma X, Zhang D, Xiang S, Duan Y, Wang T, Sun C, Wang C, Lu D, Qian M, Wang Z
Cell reports 2024 Apr 23;43(4):114003

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Systematic optimization and evaluation of culture conditions for the construction of circulating tumor cell clusters using breast cancer cell lines.

Zou J, Chen Q, He Y, Pan Y, Zhao H, Shi J, Wei Z, Yu S, Zhao Y, Han X, Lu Y, Chen W
BMC cancer 2024 Apr 23;24(1):507

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PCV2 Induced Endothelial Derived IL-8 Affects MoDCs Maturation Mainly via NF-κB Signaling Pathway.

Zhang M, Xu W, Yang N, Li Z, Zhou S, Liu X, Wang J, Li H
Viruses 2024 Apr 22;16(4)

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Caspase-1 Deficiency Modulates Adipogenesis through Atg7-Mediated Autophagy: An Inflammatory-Independent Mechanism.

Wang Y, Chen G, Xu M, Cui Y, He W, Zeng H, Zeng T, Cheng R, Li X
Biomolecules 2024 Apr 20;14(4)

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Ascorbyl palmitate ameliorates inflammatory diseases by inhibition of NLRP3 inflammasome.

Zhang L, Li G, Lin B, He H, Zhou R, Jiang W
International immunopharmacology 2024 Apr 20;131:111915

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The prevention effect of pulsed electromagnetic fields treatment on senile osteoporosis in vivo via improving the inflammatory bone microenvironment.

Zhou J, Jia F, Qu M, Ning P, Huang X, Tan L, Liu D, Zhong P, Wu Q
Electromagnetic biology and medicine 2024 Apr 2;43(1-2):46-60

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TRAF6-mediated ubiquitination of AKT in the nucleus is a critical event underlying the desensitization of G protein-coupled receptors.

Wu C, Hu L, Liu B, Zeng X, Ma H, Cao Y, Li H, Zhang X
Cell communication and signaling : CCS 2024 Apr 2;22(1):213

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Profiling the role of m6A effectors in the regulation of pluripotent reprogramming.

Wang W, Zhou L, Li H, Sun T, Wen X, Li W, Esteban MA, Hoffman AR, Hu JF, Cui J
Human genomics 2024 Apr 2;18(1):33

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miR-3188 inhibits hepatitis B virus transcription by targeting Bcl-2.

Wang S, Xie Y, Liu F, Wang J, Yang Y, Wang J, Wang Y, Hang X
Archives of virology 2024 Apr 2;169(5):88

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Dimethyl fumarate covalently modifies Cys673 of NLRP3 to exert anti-inflammatory effects.

Hu H, Cai Y, Shi Y, Zhang S, Yu X, Ma T, Liao S
iScience 2024 Apr 19;27(4):109544

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TDP-43 deficiency in suprachiasmatic nucleus perturbs rhythmicity of neuroactivity in prefrontal cortex.

Zhang H, Chen C, Zhang EE, Huang X
iScience 2024 Apr 19;27(4):109522

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The deubiquitinase cofactor UAF1 interacts with USP1 and plays an essential role in spermiogenesis.

Wang Z, Li T, Liu D, Li M, Liu S, Yu X, Li H, Song H, Zhao W, Liu Z, Chen X, Lu G, Chen ZJ, Huang T, Liu H
iScience 2024 Apr 19;27(4):109456

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Neutrophil Extracellular Traps Regulate Surgical Brain Injury by Activating the cGAS-STING Pathway.

Li B, Xu L, Wang Z, Shi Q, Cui Y, Fan W, Wu Q, Tong X, Yan H
Cellular and molecular neurobiology 2024 Apr 18;44(1):36

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Verapamil Attenuates the Severity of Tendinopathy by Mitigating Mitochondrial Dysfunction through the Activation of the Nrf2/HO-1 Pathway.

Wang Z, Dong Z, Li Y, Jiao X, Liu Y, Chang H, Gan Y
Biomedicines 2024 Apr 18;12(4)

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Resveratrol Alleviates Zearalenone-Induced Intestinal Dysfunction in Mice through the NF-κB/Nrf2/HO-1 Signalling Pathway.

Xia S, Yan C, Gu J, Yuan Y, Zou H, Liu Z, Bian J
Foods (Basel, Switzerland) 2024 Apr 17;13(8)

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KDM5C-Mediated Recruitment of BRD4 to Chromatin Regulates Enhancer Activation and BET Inhibitor Sensitivity.

Qiang Y, Fan J, Xie C, Yan L, Song X, Zhang N, Lin Y, Xiong J, Zhang W, Liu Y, Wei L, Li Y, Chen S, Liang K, Li F
Cancer research 2024 Apr 15;84(8):1252-1269

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Association of GAL-8 promoter methylation levels with coronary plaque inflammation.

Xia B, Lu Y, Liang J, Li F, Peng J, Wang J, Wan C, Ding J, Le C, Dai J, Guo B, Shen Z
International journal of cardiology 2024 Apr 15;401:131782

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Human umbilical cord mesenchymal stem cell-derived exosomes ameliorate renal fibrosis in diabetic nephropathy by targeting Hedgehog/SMO signaling.

Zhang K, Zheng S, Wu J, He J, Ouyang Y, Ao C, Lang R, Jiang Y, Yang Y, Xiao H, Li Y, Li M, Wang H, Li C, Wu D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23599

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PRMT4 interacts with NCOA4 to inhibit ferritinophagy in cisplatin-induced acute kidney injury.

Zhou L, Deng Z, Wang Y, Zhang H, Yan S, Kanwar YS, Wang Y, Dai Y, Deng F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23584

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Integrated network toxicology, molecular docking, and in vivo experiments to elucidate molecular mechanism of aflatoxin B1 hepatotoxicity.

Ge B, Yan K, Sang R, Wang W, Liu X, Yu M, Liu X, Qiu Q, Zhang X
Ecotoxicology and environmental safety 2024 Apr 15;275:116278

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Quinic acid regulated TMA/TMAO-related lipid metabolism and vascular endothelial function through gut microbiota to inhibit atherosclerotic.

Jin Q, Zhang C, Chen R, Jiang L, Li H, Wu P, Li L
Journal of translational medicine 2024 Apr 15;22(1):352

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zDHHC3-mediated S-palmitoylation of SLC9A2 regulates apoptosis in kidney clear cell carcinoma.

Zhang X, Hou J, Zhou G, Wang H, Wu Z
Journal of cancer research and clinical oncology 2024 Apr 15;150(4):194

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Taurine ameliorates sensorimotor function by inhibiting apoptosis and activating A2 astrocytes in mice after subarachnoid hemorrhage.

Yang C, Jiang Z, Gao X, Yang H, Su J, Weng R, Ni W, Gu Y
Amino acids 2024 Apr 14;56(1):31

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CCDC58 is a potential biomarker for diagnosis, prognosis, immunity, and genomic heterogeneity in pan-cancer.

Yang K, Ma Y, Chen W, Liu L, Yang Z, He C, Zheng N, Liu X, Cheng X, Song J, Chen Y, Qiao H, Zhang R
Scientific reports 2024 Apr 13;14(1):8575

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Functional analysis and validation of oncodrive gene AP3S1 in ovarian cancer through filtering of mutation data from whole-exome sequencing.

Kong D, Wu Y, Liu Q, Huang C, Wang T, Huang Z, Gao Y, Li Y, Guo H
European journal of medical research 2024 Apr 12;29(1):231

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Hawthorn Proanthocyanidin Extract Inhibits Colorectal Carcinoma Metastasis by Targeting the Epithelial-Mesenchymal Transition Process and Wnt/β-Catenin Signaling Pathway.

Wang Z, Sun Y, Wu M, Zhou L, Zheng Y, Ren T, Li M, Zhao W
Foods (Basel, Switzerland) 2024 Apr 12;13(8)

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Hazel Leaf Polyphenol Extract Alleviated Cisplatin-Induced Acute Kidney Injury by Reducing Ferroptosis through Inhibiting Hippo Signaling.

Sun M, Chang H, Jiang F, Zhang W, Yang Q, Wang X, Lv G, Lin H, Luo H, Lin Z, Wang Y
Molecules (Basel, Switzerland) 2024 Apr 11;29(8)

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Unlocking the Therapeutic Potential of a Manila Clam-Derived Antioxidant Peptide: Insights into Mechanisms of Action and Cytoprotective Effects against Oxidative Stress.

Jin H, Zhao H, Shi R, Fan F, Cheng W
Foods (Basel, Switzerland) 2024 Apr 11;13(8)

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Targeting FTO induces colorectal cancer ferroptotic cell death by decreasing SLC7A11/GPX4 expression.

Qiao Y, Su M, Zhao H, Liu H, Wang C, Dai X, Liu L, Liu G, Sun H, Sun M, Wang J, Li Z, Fan J, Zhang Q, Li C, Situ F, Xue J, Jia Z, Zhang C, Zhang S, Shan C
Journal of experimental & clinical cancer research : CR 2024 Apr 10;43(1):108

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The W195 Residue of the Newcastle Disease Virus V Protein Is Critical for Multiple Aspects of Viral Self-Regulation through Interactions between V and Nucleoproteins.

Wei Q, Wang W, Meng F, Wang Y, Wei N, Tian J, Li H, Hao Q, Zhou Z, Liu H, Yang Z, Xiao S
Viruses 2024 Apr 10;16(4)

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Protective Effects of Isoliquiritigenin and Licochalcone B on the Immunotoxicity of BDE-47: Antioxidant Effects Based on the Activation of the Nrf2 Pathway and Inhibition of the NF-κB Pathway.

Dong M, Yang Z, Gao Q, Deng Q, Li L, Chen H
Antioxidants (Basel, Switzerland) 2024 Apr 10;13(4)

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Renalase mediates macrophage-to-fibroblast crosstalk to attenuate pressure overload-induced pathological myocardial fibrosis.

Fu R, You N, Li R, Zhao X, Li Y, Li X, Jiang W
Journal of hypertension 2024 Apr 1;42(4):629-643

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Hepatic LGR4 aggravates cholestasis-induced liver injury in mice.

Gao Y, Zhai W, Sun L, Du X, Wang X, Mulholland MW, Yin Y, Zhang W
American journal of physiology. Gastrointestinal and liver physiology 2024 Apr 1;326(4):G460-G472

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Rutin mitigates fluoride-induced nephrotoxicity by inhibiting ROS-mediated lysosomal membrane permeabilization and the GSDME-HMGB1 axis involved in pyroptosis and inflammation.

Ma Y, Xu P, Xing H, Zhang Y, Li T, Ding X, Liu L, Niu Q
Ecotoxicology and environmental safety 2024 Apr 1;274:116195

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Paxillin phase separation promotes focal adhesion assembly and integrin signaling.

Liang P, Wu Y, Zheng S, Zhang J, Yang S, Wang J, Ma S, Zhang M, Gu Z, Liu Q, Jiang W, Xing Q, Wang B
The Journal of cell biology 2024 Apr 1;223(4)

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CD109 Attenuates Bleomycin-induced Pulmonary Fibrosis by Inhibiting TGF-β Signaling.

Naoi H, Suzuki Y, Miyagi A, Horiguchi R, Aono Y, Inoue Y, Yasui H, Hozumi H, Karayama M, Furuhashi K, Enomoto N, Fujisawa T, Inui N, Mii S, Ichihara M, Takahashi M, Suda T
Journal of immunology (Baltimore, Md. : 1950) 2024 Apr 1;212(7):1221-1231

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Mechanically tough, adhesive, self-healing hydrogel promotes annulus fibrosus repair via autologous cell recruitment and microenvironment regulation.

Wei Z, Ye H, Li Y, Li X, Liu Y, Chen Y, Yu J, Wang J, Ye X
Acta biomaterialia 2024 Apr 1;178:50-67

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Caged xanthone derivatives to promote mitochondria-mediated apoptosis in breast cancer cells.

Wang Y, Zheng H, Jiang X, Wu H, Ren Y, Xi Z, Zheng C, Xu H
Bioorganic & medicinal chemistry 2024 Apr 1;103:117655

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MiR-181c-5p ameliorates learning and memory in sleep-deprived mice via HMGB1/TLR4/NF-κB pathway.

Hu Y, Hu C, Yin J, Zhong J, Deng Y, Yang G
Anais da Academia Brasileira de Ciencias 2023;95(suppl 1):e20220750

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The Involvement of PGRMC1 Signaling in Cognitive Impairment Induced by Long-Term Clozapine Treatment in Rats.

Cao T, Wang L, Jiao S, Chen H, Lin C, Zhang B, Cai H
Neuropsychobiology 2023;82(6):346-358

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Semisynthesis and in Vitro Anti-cancer Effect of New Magnolol Derivatives on the Cell Proliferation, Apoptosis, Migration, and Invasion of Human Hepatocellular Carcinoma SMMC-7721 Cells.

He NN, Wang JA, Huang D, Sun XL, Ding F, Zhao L, Zhang YX, Li HM, Wu CZ
Chemical & pharmaceutical bulletin 2023;71(11):798-803

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NRF1 Alleviated Oxidative Stress of Glioblastoma Cells by Regulating NOR1.

Wang J, Chen S, Xiang W, Zhu Q, Ren N
Folia biologica 2023;69(1):13-21

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FNDC5 Attenuates Atherosclerotic Plaque Formation and Regulates PPARα/HO-1 in ApoE-/- Mice.

Zhou B, Wang X, Wang Y, Liu D
Journal of vascular research 2023;60(3):172-182

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CDKs Functional Analysis in Low Proliferating Early-Stage Pancreatic Ductal Adenocarcinoma.

Zhu S, Yang H, Liu L, Jiang Z, Ji J, Wang X, Zhong L, Liu F, Gao X, Wang H, Zhou Y
Journal of bioinformatics and systems biology : Open access 2023;6(3):187-200

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Phenolic profile, antioxidation and anti-proliferation activity of phenolic-rich extracts from Sanghuangporusvaninii.

Gao H, Yin C, Li C, Li Y, Shi D, Fan X, Yao F, Wu W, Li J
Current research in food science 2023;6:100519

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Coptis chinensis and Berberine Ameliorate Chronic Ulcerative Colitis: An Integrated Microbiome-Metabolomics Study.

Zhou R, Huang Y, Tian C, Yang Y, Zhang Z, He K
The American journal of Chinese medicine 2023;51(8):2195-2220

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Baicalin Ameliorates Lung Injury in Rats by Inhibiting NLRP3 Inflammasome Activation via NF-[Formula: see text]B Signaling Pathway.

Yang X, Han J, Huan Z, Xu C, Wang Q, Ge X
The American journal of Chinese medicine 2023;51(4):979-996

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Amelioration of Lung Fibrosis by Total Flavonoids of Astragalus via Inflammatory Modulation and Epithelium Regeneration.

Yang CG, Mao XL, Wu JF, An X, Cao JJ, Zhang XY, Li M, Zhang FF
The American journal of Chinese medicine 2023;51(2):373-389

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Baicalin Reduces Immune Cell Infiltration by Inhibiting Inflammation and Protecting Tight Junctions in Ischemic Stroke Injury.

Hao Z, Zhang Z, Zhao Y, Wang D
The American journal of Chinese medicine 2023;51(2):355-372

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Triamcinolone acetonide induces the autophagy of Ag85B-treated WI-38 cells via SIRT1/FOXO3 pathway.

Luo L, Zhou L, Luo L, Feng D, Ding Y, Lu Z, Nie G, Bai L, Xiao Y
Allergologia et immunopathologia 2023;51(2):27-35

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Propofol improves ischemia reperfusion-induced liver fibrosis by regulating lncRNA HOXA11-AS.

Luo J, Liu J, Mou Y, Luo F, Liao Q, Liao Y
The Journal of toxicological sciences 2023;48(6):345-354

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Methylthioacetic acid, a derivative of aroma compounds from Cucumis melo var. conomon dose-dependently triggers differentiation and apoptosis of RCM-1 human colorectal cancer cells.

Kamimura M, Sasaki A, Otani Y, Nakamura Y, Nakamura T, Kuramochi K, Imai T, Kubo N, Okamoto S
The Journal of toxicological sciences 2023;48(1):25-35

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ESE-1 mediates lipopolysaccharide-induced BV2 cell inflammation via upregulation of HMGB1 expression.

Lu Y, Ding J, Huang J, Zhao Y
Journal of biosciences 2023;48

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Ponicidin Induces Apoptosis of Murine Melanoma by Inhibiting the NF-κB Signaling Pathway.

Wang L, Lou X, Wang D, Lu K, Zhang S, Cheng B
Biological & pharmaceutical bulletin 2023;46(6):803-810

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C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways.

Chen Y, Liu Y, Li H, Huna R, Tan X, Li N, Zhang Y, Jiao X, Liu M
Journal of applied oral science : revista FOB 2023;31:e20220404

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Exploring the Targets and Molecular Mechanisms of Thalidomide in the Treatment of Ulcerative Colitis: Network Pharmacology and Experimental Validation.

Li J, Tao Q, Xie Y, Wang P, Jin R, Huang X, Chen Y, Zeng C
Current pharmaceutical design 2023;29(34):2721-2737

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Lycium barbarum Polysaccharides Regulating miR-181/Bcl-2 Decreased Autophagy of Retinal Pigment Epithelium with Oxidative Stress.

Yang YJ, Wang Y, Deng Y, Liu XQ, Lu J, Peng J, Li J, Zhou YS, Zhu HA, Li B, Qin YH, Peng QH
Oxidative medicine and cellular longevity 2023;2023:9554457

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Gossypol Affects Viral Replication by Inhibiting Pseudorabies Virus Adsorption.

Bai Y, Su B, Cheng X, Liu Q, Zeng L, Fu P
Transboundary and emerging diseases 2023;2023:9073566

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STK24 Promotes Progression of LUAD and Modulates the Immune Microenvironment.

Li Y, Liu Y, Wang K, Xue D, Huang Y, Tan Z, Chen Y
Mediators of inflammation 2023;2023:8646088

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Pterostilbene Confers Protection against Diquat-Induced Intestinal Damage with Potential Regulation of Redox Status and Ferroptosis in Broiler Chickens.

Chen Y, Zhang H, Li Y, Wang T
Oxidative medicine and cellular longevity 2023;2023:8258354

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Exploring the Effect of Compound Glycyrrhizin and Silybinin on the Metabolism of Pexidartinib in Rats Based on CYP3A4 and CYP2C9.

Su Y, Wei X, Cheng Q, Qi H, Chen J, Qiu XJ
Advances in pharmacological and pharmaceutical sciences 2023;2023:6737062

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JFD, a Novel Natural Inhibitor of Keap1 Alkylation, Suppresses Intracellular Mycobacterium Tuberculosis Growth through Keap1/Nrf2/SOD2-Mediated ROS Accumulation.

Wan H, Cai Y, Xiao L, Ling Y, Ge L, Mo S, Xie Q, Peng S, Zhou B, Zeng X, Chen X
Oxidative medicine and cellular longevity 2023;2023:6726654

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Xuanhuang Runtong Tablets Relieve Slow Transit Constipation in Mice by Regulating TLR5/IL-17A Signaling Mediated by Gut Microbes.

Liang X, Wan D, Cai Y, Yue W, Wang X, Zhou H, Zhou R, Du Q, Xiao J, Zhang S
Evidence-based complementary and alternative medicine : eCAM 2023;2023:6506244

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Network Pharmacology-Based Identification of Key Targets of Ziyin Mingmu Pills Acting on Age-Related Macular Degeneration.

Yang Y, Wang Y, Liu X, Deng Y, Lu J, Jiang F, Nie F, Peng J, Peng Q, Qin Y
Evidence-based complementary and alternative medicine : eCAM 2023;2023:5933125

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Inhibition of miR-182-5p Targets FGF9 to Alleviate Osteoarthritis.

Sun Y, Su S, Li M, Deng A
Analytical cellular pathology (Amsterdam) 2023;2023:5911546

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Human Umbilical Cord Mesenchymal Stem Cells Inhibit Pyroptosis of Renal Tubular Epithelial Cells through miR-342-3p/Caspase1 Signaling Pathway in Diabetic Nephropathy.

Zheng S, Zhang K, Zhang Y, He J, Ouyang Y, Lang R, Ao C, Jiang Y, Xiao H, Li Y, Li M, Li C, Wu D
Stem cells international 2023;2023:5584894

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Vasoprotective Effects of Hyperoside against Cerebral Ischemia/Reperfusion Injury in Rats: Activation of Large-Conductance Ca(2+)-Activated K(+) Channels.

Hong WM, Xie YW, Zhao MY, Yu TH, Wang LN, Xu WY, Gao S, Cai HB, Guo Y, Zhang F
Neural plasticity 2023;2023:5545205

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The Interaction of Apelin and FGFR1 Ameliorated the Kidney Fibrosis through Suppression of TGFβ-Induced Endothelial-to-Mesenchymal Transition.

Gao R, Wu Y, Yang Q, Chen L, Chen J, Wang B, Liu Z, Jin J, Li J, Wu G
Oxidative medicine and cellular longevity 2023;2023:5012474

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A New Porcine Reproductive and Respiratory Syndrome Virus with N-Linked Glycosylation Site Deletion in GP5 44th Amino Acid from JXA1, NADC30-Like, and JM Triparental Recombination.

Zhou X, Bian S, Kan E, Zhou L, Zhang X, Xiao M, Lu C, Hua J, Wu Y, Zhang C, Zhou Y, Dong W, Du J, Wang X, Song H
Transboundary and emerging diseases 2023;2023:4001055

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QiHuangYiShen Granules Modulate the Expression of LncRNA MALAT1 and Attenuate Epithelial-Mesenchymal Transition in Kidney of Diabetic Nephropathy Rats.

Yuan LS, Du H, Ren QY, Yang RL, Liu SW, Liu SY, Shi KF, Wang B, Meng XF, Li TX, Zhang N
Evidence-based complementary and alternative medicine : eCAM 2023;2023:3357281

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Calpain-2 Facilitates Autophagic/Lysosomal Defects and Apoptosis in ARPE-19 Cells and Rats Induced by Exosomes from RPE Cells under NaIO(3) Stimulation.

Zhang S, Qiu Y, Feng Y, Zhang Y, Li Y, Wang B, Wei H, Chen X, Shen L, Li W, Zheng L, Zhang Y
Oxidative medicine and cellular longevity 2023;2023:3310621

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Upregulation of NDUFAF2 in Lung Adenocarcinoma Is a Novel Independent Prognostic Biomarker.

Zou K, Gao P, Xu X, Zhang W, Zeng Z
Computational and mathematical methods in medicine 2023;2023:2912968

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Microbiota from Exercise Mice Counteracts High-Fat High-Cholesterol Diet-Induced Cognitive Impairment in C57BL/6 Mice.

Li R, Liu R, Chen L, Wang G, Qin L, Yu Z, Wan Z
Oxidative medicine and cellular longevity 2023;2023:2766250

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Characterization of TIM-3 Expression and Its Correlation with TNF-α and IFN-γ in Patients with Surgically Resected Lung Adenocarcinoma.

Tan J, Shen P, Yang X, Cai W, Liao H
Disease markers 2023;2023:2352945

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Prevention of Bleomycin-Induced Pulmonary Inflammation and Fibrosis in Mice by Bilobalide.

Zhang X, Zhang W, Chen X, Cai Y
Evidence-based complementary and alternative medicine : eCAM 2023;2023:1973163

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Leonurine Regulates Hippocampal Nerve Regeneration in Rats with Chronic and Unpredictable Mild Stress by Activating SHH/GLI Signaling Pathway and Restoring Gut Microbiota and Microbial Metabolic Homeostasis.

Meng P, Zhang X, Li D, Yang H, Lin X, Zhao H, Li P, Wang Y, Wang X, Ge J
Neural plasticity 2023;2023:1455634

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Traxoprodil Produces Antidepressant-Like Behaviors in Chronic Unpredictable Mild Stress Mice through BDNF/ERK/CREB and AKT/FOXO/Bim Signaling Pathway.

Wang Y, Liang Z, Song W, Qin Y, Todd N, Gao M
Oxidative medicine and cellular longevity 2023;2023:1131422

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Anomanolide C suppresses tumor progression and metastasis by ubiquitinating GPX4-driven autophagy-dependent ferroptosis in triple negative breast cancer.

Chen YM, Xu W, Liu Y, Zhang JH, Yang YY, Wang ZW, Sun DJ, Li H, Liu B, Chen LX
International journal of biological sciences 2023;19(8):2531-2550

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Berberine inhibits high fat diet-associated colorectal cancer through modulation of the gut microbiota-mediated lysophosphatidylcholine.

Chen H, Ye C, Wu C, Zhang J, Xu L, Wang X, Xu C, Zhang J, Guo Y, Yao Q
International journal of biological sciences 2023;19(7):2097-2113

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NLRP3 Inflammasome Mediates Silica-induced Lung Epithelial Injury and Aberrant Regeneration in Lung Stem/Progenitor Cell-derived Organotypic Models.

Zhou H, Zhang Q, Huang W, Zhou S, Wang Y, Zeng X, Wang H, Xie W, Kong H
International journal of biological sciences 2023;19(6):1875-1893

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M6A-modified circRBM33 promotes prostate cancer progression via PDHA1-mediated mitochondrial respiration regulation and presents a potential target for ARSI therapy.

Zhong C, Long Z, Yang T, Wang S, Zhong W, Hu F, Teoh JY, Lu J, Mao X
International journal of biological sciences 2023;19(5):1543-1563

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Development and anticancer properties of Up284, a spirocyclic candidate ADRM1/RPN13 inhibitor.

Anchoori RK, Anchoori V, Lam B, Tseng SH, Das S, Velasquez FC, Karanam B, Poddatoori D, Patnam R, Rudek MA, Chang YN, Roden RBS
PloS one 2023;18(6):e0285221

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Combinatorial expression of ebony and tan generates body color variation from nymph through adult stages in the cricket, Gryllus bimaculatus.

Inoue S, Watanabe T, Hamaguchi T, Ishimaru Y, Miyawaki K, Nikawa T, Takahashi A, Noji S, Mito T
PloS one 2023;18(5):e0285934

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Mitochondrial decline in the ageing old world primate retina: Little evidence for difference between the centre and periphery.

Kam JH, Shinhmar H, Powner MB, Hayes MJ, Aboelnour A, Jeffery G
PloS one 2023;18(5):e0273882

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Downregulation of KIAA1199 alleviated the activation, proliferation, and migration of hepatic stellate cells by the inhibition of epithelial-mesenchymal transition.

Liu J, Xia S, Han P, Zhang M, Wu J, Liao J
Open medicine (Warsaw, Poland) 2023;18(1):20230689

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Identification and Characterization of a Novel Nanobody Against Human CTGF to Reveal Its Antifibrotic Effect in an in vitro Model of Liver Fibrosis.

Liu R, Zhu M, Chen J, Gai J, Huang J, Zhou Y, Wan Y, Tu C
International journal of nanomedicine 2023;18:5407-5422

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Glycosylation-Engineered Platelet Membrane-Coated Interleukin 10 Nanoparticles for Targeted Inhibition of Vascular Restenosis.

Li F, Rong Z, Chen T, Wang P, Di X, Ni L, Liu C
International journal of nanomedicine 2023;18:5011-5030

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Integrated Network Pharmacology, Molecular Docking and Animal Experiment to Explore the Efficacy and Potential Mechanism of Baiyu Decoction Against Ulcerative Colitis by Enema.

Cui Y, Hu J, Li Y, Au R, Fang Y, Cheng C, Xu F, Li W, Wu Y, Zhu L, Shen H
Drug design, development and therapy 2023;17:3453-3472

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Jiawei Danxuan Koukang Alleviates Arecoline Induced Oral Mucosal Lesions: Network Pharmacology and the Combined Ultra-High Performance Liquid Chromatography (UPLC) and Mass Spectrometry (MS).

Zhou L, Tan J, Dai Y, Zhu K, Xiao Y, Wu D, Wang Z, Tan Y, Qin Y
Drug design, development and therapy 2023;17:3085-3101

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10-Gingerol Enhances the Effect of Taxol in Triple-Negative Breast Cancer via Targeting ADRB2 Signaling.

Liang Y, Wu G, Luo T, Xie H, Zuo Q, Huang P, Li H, Chen L, Lu H, Chen Q
Drug design, development and therapy 2023;17:129-142

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K(+)/Cl(-) cotransporter 2 (KCC2) and Na(+)/HCO3- cotransporter 1 (NBCe1) interaction modulates profile of KCC2 phosphorylation.

Pethe A, Hamze M, Giannaki M, Heimrich B, Medina I, Hartmann AM, Roussa E
Frontiers in cellular neuroscience 2023;17:1253424

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EFEMP1 is a potential biomarker of choroid thickness change in myopia.

Shi WQ, Wan T, Li B, Li T, Zhou XD
Frontiers in neuroscience 2023;17:1144421

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Network pharmacology reveals that Berberine may function against Alzheimer's disease via the AKT signaling pathway.

Wei W, Yao JX, Zhang TT, Wen JY, Zhang Z, Luo YM, Cao Y, Li H
Frontiers in neuroscience 2023;17:1059496

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Semaphorin4F is a potential biomarker for clinical progression and prognosis in gastric cancer.

Wang H, Ji X, Chen L, Ju L, Ma Q, Wu Y, Cai W
International journal of clinical and experimental pathology 2023;16(9):210-224

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Establishment of Risk Model and Analysis of Immunoinfiltration Based on Mitophagy-Related Associated Genes in Atrial Fibrillation.

Sang W, Wang L, Yan X, Sun H, Han Y, Wang F, Tang B, Li Y
Journal of inflammation research 2023;16:2561-2583

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Comprehensive Analysis of NABP2 as a Prognostic Biomarker and Its Correlation with Immune Infiltration in Hepatocellular Carcinoma.

Li B, Liu J, Xu L, Xu Q, Liu Z, Liu T
Journal of inflammation research 2023;16:1783-1804

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Integrated proteomics and metabolomics analysis of D-pinitol function during hippocampal damage in streptozocin-induced aging-accelerated mice.

Li X, Gao Y, Li B, Zhao W, Cai Q, Yin W, Zeng S, Li X, Gao H, Cheng M
Frontiers in molecular neuroscience 2023;16:1251513

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Sex Differences in Genomic Features of Hepatitis B-Associated Hepatocellular Carcinoma With Distinct Antitumor Immunity.

Xu C, Cheng S, Chen K, Song Q, Liu C, Fan C, Zhang R, Zhu Q, Wu Z, Wang Y, Fan J, Zheng H, Lu L, Chen T, Zhao H, Jiao Y, Qu C
Cellular and molecular gastroenterology and hepatology 2023;15(2):327-354

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HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

Yuan J, Lv T, Yang J, Wu Z, Yan L, Yang J, Shi Y, Jiang L
Cellular and molecular gastroenterology and hepatology 2023;15(2):307-325

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CKIP-1 mediates P. gingivalis-suppressed osteogenic/cementogenic differentiation of periodontal ligament cells partially via p38 signaling pathway.

Huang X, Xiao J, Wang H, Peng Y, Liu H, Ma L, Wang X, Cao Z
Journal of oral microbiology 2023;15(1):2236427

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Slc6a13 Deficiency Attenuates Pasteurella multocida Infection-Induced Inflammation via Glycine-Inflammasome Signaling.

He F, Qiu Y, Wu X, Xia Y, Yang L, Wu C, Li P, Zhang R, Fang R, Li N, Peng Y
Journal of innate immunity 2023;15(1):107-121

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PIWI-interacting RNA-17458 is oncogenic and a potential therapeutic target in cervical cancer.

Liu L, Li L, Zu W, Jing J, Liu G, Sun T, Xie Q
Journal of Cancer 2023;14(9):1648-1659

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A Positive Feedback Loop of E2F4-Mediated Activation of MNX1 Regulates Tumour Progression in Colorectal Cancer.

Li JK, Liu H, Zhang HW, Li J, Liang ZT
Journal of Cancer 2023;14(14):2739-2750

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ALDOB plays a tumor-suppressive role by inhibiting AKT activation in gastric cancer.

Peng C, Yang X, Li X, Ye Z, Wang J, Wu W
Journal of Cancer 2023;14(12):2255-2262

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Up-regulation of ABCG1 is associated with methotrexate resistance in acute lymphoblastic leukemia cells.

Chen Y, Fang H, Sun H, Wu X, Xu Y, Zhou BS, Li H
Frontiers in pharmacology 2023;14:1331687

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Integration of RRBS and RNA-seq unravels the regulatory role of DNMT3A in porcine Sertoli cell proliferation.

Xu D, Yan S, Jin H, Chen C, Tang X, Wang X, Li Y, Fei F, Yang A
Frontiers in genetics 2023;14:1302351

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Major vault protein regulates tumor-associated macrophage polarization through interaction with signal transducer and activator of transcription 6.

Yu C, Zhu Q, Ma C, Luo C, Nie L, Cai H, Wang Q, Wang F, Ren H, Yan H, Xu K, Zhou L, Zhang C, Lu G, Lu Z, Zhu Y, Liu S
Frontiers in immunology 2023;14:1289795

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Secondary metabolites of Bacillus subtilis L2 show antiviral activity against pseudorabies virus.

Wang X, Hao G, Zhou M, Chen M, Ling H, Shang Y
Frontiers in microbiology 2023;14:1277782

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Direct interaction of the molecular chaperone GRP78/BiP with the Newcastle disease virus hemagglutinin-neuraminidase protein plays a vital role in viral attachment to and infection of culture cells.

Han C, Xie Z, Lv Y, Liu D, Chen R
Frontiers in immunology 2023;14:1259237

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Tangeretin attenuates bleomycin-induced pulmonary fibrosis by inhibiting epithelial-mesenchymal transition via the PI3K/Akt pathway.

Li J, Wei Q, Song K, Wang Y, Yang Y, Li M, Yu J, Su G, Peng L, Fu B, Yi P
Frontiers in pharmacology 2023;14:1247800

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6-Gingerol alleviates placental injury in preeclampsia by inhibiting oxidative stress via BNIP3/LC3 signaling-mediated trophoblast mitophagy.

Li A, Zhao M, Yang Z, Fang Z, Qi W, Zhang C, Zhou M, Guo J, Li S, Wang X, Zhang M
Frontiers in pharmacology 2023;14:1243734

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Transcriptome sequencing and functional verification revealed the roles of exogenous magnesium in tobacco anti-PVY infection.

Guo H, Xu C, Wang F, Jiang L, Lei X, Zhang M, Li R, Lan X, Xia Z, Wang Z, Wu Y
Frontiers in microbiology 2023;14:1232279

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Artesunate, as an Hsp90 inhibitor, inhibits the proliferation of Burkitt's lymphoma cells by inhibiting AKT and ERK.

Yuan-Ce L, Qi Z, Hong-Yang Z, Yan-Wen W, Yu-Mei S, Bi-Juan Y, Jun-Lin Y
Frontiers in pharmacology 2023;14:1218467

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Choroidal circulation disturbance is an initial factor in outer retinal degeneration in rats under simulated weightlessness.

Mu Y, Wei D, Yao L, Xu X, Li S, Cao R, Chen T, Zhang Z
Frontiers in physiology 2023;14:1198862

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Electroacupuncture alleviates ulcerative colitis by targeting CXCL1: evidence from the transcriptome and validation.

Zhang RB, Dong LC, Shen Y, Li HY, Huang Q, Yu SG, Wu QF
Frontiers in immunology 2023;14:1187574

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Cholesterol 25-hydroxylase suppresses avian reovirus replication by its enzymatic product 25-hydroxycholesterol.

Wang Y, Zuo W, Zhang Y, Bo Z, Zhang C, Zhang X, Wu Y
Frontiers in microbiology 2023;14:1178005

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Acute murine cytomegalovirus infection boosts cell-type specific response and lipid metabolism changes in the liver of infant mice.

Gao J, Wang A, Bu X, Jia W
Frontiers in immunology 2023;14:1169869

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African swine fever virus pA104R protein acts as a suppressor of type I interferon signaling.

Chen Q, Li L, Guo S, Liu Z, Liu L, Tan C, Chen H, Wang X
Frontiers in microbiology 2023;14:1169699

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Role of asparagine biosynthesis pathway in Siniperca chuatsi rhabdovirus proliferation.

Li F, Fu X, Luo X, Lin Q, Liang H, Niu Y, Liu L, Li N
Frontiers in microbiology 2023;14:1165491

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Probiotics treatment ameliorated mycophenolic acid-induced colitis by enhancing intestinal barrier function and improving intestinal microbiota dysbiosis in mice.

Zhang P, Chen J, Ming Y, Niu Y
Frontiers in microbiology 2023;14:1153188

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Tetrandrine inhibits the proliferation of mesangial cells induced by enzymatically deglycosylated human IgA1 via IgA receptor/MAPK/NF-κB signaling pathway.

Xu W, Song W, Chen S, Jin S, Xue X, Min J, Wang X, You P
Frontiers in pharmacology 2023;14:1150829

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Gut microbiota from sigma-1 receptor knockout mice induces depression-like behaviors and modulates the cAMP/CREB/BDNF signaling pathway.

Li JH, Liu JL, Li XW, Liu Y, Yang JZ, Chen LJ, Zhang KK, Xie XL, Wang Q
Frontiers in microbiology 2023;14:1143648

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E. coli Nissle 1917 ameliorates mitochondrial injury of granulosa cells in polycystic ovary syndrome through promoting gut immune factor IL-22 via gut microbiota and microbial metabolism.

Luo M, Chen Y, Pan X, Chen H, Fan L, Wen Y
Frontiers in immunology 2023;14:1137089

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Apilimod activates the NLRP3 inflammasome through lysosome-mediated mitochondrial damage.

Hou Y, He H, Ma M, Zhou R
Frontiers in immunology 2023;14:1128700

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Identification and validation of hub genes in drug induced acute kidney injury basing on integrated transcriptomic analysis.

Deng YX, Liu K, Qiu QX, Tang ZY, Que RM, Li DK, Gu XR, Zhou GL, Wu YF, Zhou LY, Yin WJ, Zuo XC
Frontiers in immunology 2023;14:1126348

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Protective effects of Scutellariae Radix Carbonisata-derived carbon dots on blood-heat and hemorrhage rats.

Zhang M, Cheng J, Luo J, Li C, Hou T, Zhao Y, Wang Y, Qu H, Kong H
Frontiers in pharmacology 2023;14:1118550

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TIGAR deficiency induces caspase-1-dependent trophoblasts pyroptosis through NLRP3-ASC inflammasome.

Guo J, Zhou M, Zhao M, Li S, Fang Z, Li A, Zhang M
Frontiers in immunology 2023;14:1114620

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Dendrobium mixture ameliorates type 2 diabetes mellitus with non-alcoholic fatty liver disease through PPAR gamma: An integrated study of bioinformatics analysis and experimental verification.

Zhuang S, Zhang J, Lin X, Wang X, Yu W, Shi H
Frontiers in pharmacology 2023;14:1112554

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Effect of acupuncture on the opening time of implantation window and endometrial receptivity in controlled ovarian hyperstimulation rats during peri-implantation period.

Hu R, Huang Y, Song Y, Wu X, Song K, Huang G, Zhang M, Dong H
Frontiers in endocrinology 2023;14:1110266

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Dietary fiber alters immunity and intestinal barrier function of different breeds of growing pigs.

Ding S, Cheng Y, Azad MAK, Dong H, He J, Huang P, Kong X
Frontiers in immunology 2023;14:1104837

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The TRPM4 channel inhibitor 9-phenanthrol alleviates cerebral edema after traumatic brain injury in rats.

Ma P, Huang N, Tang J, Zhou Z, Xu J, Chen Y, Zhang M, Huang Q, Cheng Y
Frontiers in pharmacology 2023;14:1098228

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Sirtuin 1 activator alleviated lethal inflammatory injury via promotion of autophagic degradation of pyruvate kinase M2.

Zhao S, Sun Y, Wu X, Yang Y, Fan K, Hu K, Qin Y, Li K, Lin L, Chen K, Ma Y, Zhu M, Liu G, Zhang L
Frontiers in pharmacology 2023;14:1092943

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Identification of immune signatures in Parkinson's disease based on co-expression networks.

Dong X, Li Y, Li Q, Li W, Wu G
Frontiers in genetics 2023;14:1090382

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RUNX1/CD44 axis regulates the proliferation, migration, and immunotherapy of gliomas: A single-cell sequencing analysis.

Zhang H, Cao H, Luo H, Zhang N, Wang Z, Dai Z, Wu W, Liu G, Xie Z, Cheng Q, Cheng Y
Frontiers in immunology 2023;14:1086280

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Integrated analysis of Dendrobium nobile extract Dendrobin A against pancreatic ductal adenocarcinoma based on network pharmacology, bioinformatics, and validation experiments.

Xu X, Yu Y, Yang L, Wang B, Fan Y, Ruan B, Zhang X, Dai H, Mei W, Jie W, Zheng S
Frontiers in pharmacology 2023;14:1079539

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The prognostic value of the GPAT/AGPAT gene family in hepatocellular carcinoma and its role in the tumor immune microenvironment.

Wen P, Wang R, Xing Y, Ouyang W, Yuan Y, Zhang S, Liu Y, Peng Z
Frontiers in immunology 2023;14:1026669

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A strategy of local hydrogen capture and catalytic hydrogenation for enhanced therapy of chronic liver diseases.

Tao G, Liu F, Jin Z, Liu B, Wang H, Li D, Tang W, Chen Y, He Q, Qin S
Theranostics 2023;13(8):2455-2470

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Platelets promote CRC by activating the C5a/C5aR1 axis via PSGL-1/JNK/STAT1 signaling in tumor-associated macrophages.

Li X, Chen X, Gong S, Zhao J, Yao C, Zhu H, Xiao R, Qin Y, Li R, Sun N, Li X, Dong F, Zhao T, Pan Y, Yang J
Theranostics 2023;13(6):2040-2056

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ZY-444 inhibits the growth and metastasis of prostate cancer by targeting TNFAIP3 through TNF signaling pathway.

Han MT, Pei H, Sun QQ, Wang CL, Li P, Xie YY, Cao LJ, Zhang XX, Sun ZL
American journal of cancer research 2023;13(4):1533-1546

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IRG1/Itaconate induces metabolic reprogramming to suppress ER-positive breast cancer cell growth.

Wang HC, Chang WC, Lee DY, Li XG, Hung MC
American journal of cancer research 2023;13(3):1067-1081

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DNMT1 mediates the disturbed flow-induced endothelial to mesenchymal transition through disrupting β-alanine and carnosine homeostasis.

Zhao J, Zhao C, Yang F, Jiang Z, Zhu J, Yao W, Pang W, Zhou J
Theranostics 2023;13(13):4392-4411

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Network pharmacology and experimental verification reveal the mechanism of safranal against glioblastoma (GBM).

Yang X, Lu D, Sun Y, Wei T, Man D, Chen A, Luo T, Zhao F, Liu X, Cheng B, Wang X, Zhao P, Wang D, Li X
Frontiers in oncology 2023;13:1255164

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BPOZ-2 is a negative regulator of the NLPR3 inflammasome contributing to SARS-CoV-2-induced hyperinflammation.

Li J, Lin H, Fan T, Huang L, Zhang X, Tai Y, Fang Y, Li Q, Zhao R, Wang P, Zhou L, Wan L, Wu Y, Zhong H, Wei C, Yang X
Frontiers in cellular and infection microbiology 2023;13:1134511

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Study on the protective effect of OM-MSCs on Golgi apparatus after intracerebral hemorrhage in Sprague-Dawley rats.

Liu J, Hu Z, Huang Y, Zhang Y, Peng D
American journal of stem cells 2023;12(5):124-137

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Peptidomics insights: neutrophil extracellular traps (NETs) related to the chronic subdural hemorrhage.

Li J, Zhao J, Sun S, Shen S, Zhong B, Dong X
PeerJ 2023;11:e16676

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Choline regulation of triglycerides synthesis through ubiquintination pathway in MAC-T cells.

Hu M, Liu L
PeerJ 2023;11:e16611

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Selective HDAC6 inhibitor TubA offers neuroprotection after intracerebral hemorrhage via inhibiting neuronal apoptosis.

Peng C, Gong X, Hu Z, Chen C, Jiang Z
PeerJ 2023;11:e15293

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Investigation of anti-diabetic effect of a novel coenzyme Q10 derivative.

Tan X, Yang X, Xu X, Peng Y, Li X, Deng Y, Zhang X, Qiu W, Wu D, Ruan Y, Zhi C
Frontiers in chemistry 2023;11:1280999

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Tanshinone IIA inhibits cardiomyocyte pyroptosis through TLR4/NF-κB p65 pathway after acute myocardial infarction.

Chai R, Ye Z, Xue W, Shi S, Wei Y, Hu Y, Wu H
Frontiers in cell and developmental biology 2023;11:1252942

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Evidence for developmental vascular-associated necroptosis and its contribution to venous-lymphatic endothelial differentiation.

Meng H, Zhao Y, Li Y, Fan H, Yi X, Meng X, Wang P, Fu F, Wu S, Wang Y
Frontiers in cell and developmental biology 2023;11:1229788

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Role of UDP-glucose ceramide glucosyltransferase in venous malformation.

Chen S, Wang Y, Kong L, Ji Y, Cui J, Shen W
Frontiers in cell and developmental biology 2023;11:1178045

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The combination of NDUFS1 with CD4(+) T cell infiltration predicts favorable prognosis in kidney renal clear cell carcinoma.

Wu D, He L, Xu Z, Tian RF, Fan XY, Fan J, Ai J, Bian HJ, Qin WJ, Qin J, Li L
Frontiers in cell and developmental biology 2023;11:1168462

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Silencing Glypican-1 enhances the antitumor effects of Pictilisib via downregulating PI3K/Akt/ERK signaling in chemo-resistant esophageal adenocarcinoma.

Pratap A, Qualman A, Garrett H, Westbrook L, The E, Mitra S, Cordero M, Monge KM, Idrovo JP, Chauhan A, Cheng L, Cohen MJ, Mungo B, Wani S, Meguid RA, McCarter MD, Meng X
Molecular & cellular oncology 2023;10(1):2238873

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Effect of blood flow-restricted resistance training on myocardial fibrosis in early spontaneously hypertensive rats.

Tan Z, Chen P, Zheng Y, Pan Y, Wang B, Zhao Y
Frontiers in cardiovascular medicine 2023;10:1101748

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Inhibition of tiRNA-Gly-GCC ameliorates neointimal formation via CBX3-mediated VSMCs phenotypic switching.

Rong Z, Li F, Zhang R, Niu S, Di X, Ni L, Liu C
Frontiers in cardiovascular medicine 2023;10:1030635

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Role of NLRP3 inflammasome activation in HCC cell progression.

Dai B, Cao H, Hu Y, Gong Z, Huang X, Chen Y, Liu F, Peng X, Zhang Y, Lei X
Heliyon 2023 Sep;9(9):e19542

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Electroacupuncture preconditioning protects against myocardial ischemia-reperfusion injury by modulating dynamic inflammatory response.

Bai H, Xu SL, Shi JJ, Ding YP, Liu QQ, Jiang CH, He LL, Zhang HR, Lu SF, Gu YH
Heliyon 2023 Sep;9(9):e19396

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MAVI1, an endoplasmic reticulum-localized microprotein, suppresses antiviral innate immune response by targeting MAVS on mitochondrion.

Shi TT, Huang Y, Li Y, Dai XL, He YH, Ding JC, Ran T, Shi Y, Yuan Q, Li WJ, Liu W
Science advances 2023 Sep;9(35):eadg7053

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WBP2 restrains the lysosomal degradation of GPX4 to inhibit ferroptosis in cisplatin-induced acute kidney injury.

Deng Z, Wang Y, Liu J, Zhang H, Zhou L, Zhao H, Han Y, Yan S, Dong Z, Wang Y, Dai Y, Deng F
Redox biology 2023 Sep;65:102826

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Transcription Factor BCL11A Regulates Schwann Cell Behavior During Peripheral Nerve Regeneration.

Zhang Y, Shen Y, Zhao L, Zhao Q, Zhao L, Yi S
Molecular neurobiology 2023 Sep;60(9):5352-5365

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Moderate Intensity of Treadmill Exercise Rescues TBI-Induced Ferroptosis, Neurodegeneration, and Cognitive Impairments via Suppressing STING Pathway.

Chen J, Zhu T, Yu D, Yan B, Zhang Y, Jin J, Yang Z, Zhang B, Hao X, Chen Z, Yan C, Yu J
Molecular neurobiology 2023 Sep;60(9):4872-4896

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TRIM9 promotes Müller cell-derived retinal stem cells to differentiate into retinal ganglion cells by regulating Atoh7.

Zeng Q, Zhou J, Hua X
In vitro cellular & developmental biology. Animal 2023 Sep;59(8):586-595

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Isoquercitrin Played a Neuroprotective Role in Rats After Cerebral Ischemia/Reperfusion Through Up-Regulating Neuroglobin and Anti-Oxidative Stress.

Li X, Yi L, Liu X, Chen X, Chen S, Cai S
Transplantation proceedings 2023 Sep;55(7):1751-1761

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Hypoxia caused by unilateral nasal obstruction decreases mandibular density in rats through inhibition of Cyp1a1 expression.

Xu Y, Wang Y, Xiao H, Li Y
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2023 Sep;52(8):786-794

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Sophoricoside attenuates autoimmune‑mediated liver injury through the regulation of oxidative stress and the NF‑κB signaling pathway.

Chen Y, Lei Y, Wang H, Wang L, Xu J, Wang S, Yu M, Peng Z, Xiao F, Tian D, Liu M
International journal of molecular medicine 2023 Sep;52(3)

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FBXO28 suppresses liver cancer invasion and metastasis by promoting PKA-dependent SNAI2 degradation.

Qiao X, Lin J, Shen J, Chen Y, Zheng L, Ren H, Zhao X, Yang H, Li P, Wang Z
Oncogene 2023 Sep;42(39):2878-2891

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Klotho-beta attenuates Rab8a-mediated exosome regulation and promotes prostate cancer progression.

Wu T, Zhang Y, Han Q, Lu X, Cheng Y, Chen J, Sha J, Xia W
Oncogene 2023 Sep;42(38):2801-2815

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The Circadian System Is Essential for the Crosstalk of VEGF-Notch-mediated Endothelial Angiogenesis in Ischemic Stroke.

Zhang Y, Zhao X, Guo C, Zhang Y, Zeng F, Yin Q, Li Z, Shao L, Zhou D, Liu L
Neuroscience bulletin 2023 Sep;39(9):1375-1395

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Cuproptosis enhances docetaxel chemosensitivity by inhibiting autophagy via the DLAT/mTOR pathway in prostate cancer.

Wen H, Qu C, Wang Z, Gao H, Liu W, Wang H, Sun H, Gu J, Yang Z, Wang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Sep;37(9):e23145

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Pinocembrin alleviates pyroptosis and apoptosis through ROS elimination in random skin flaps via activation of SIRT3.

Li J, Li Y, Wang X, Xie Y, Lou J, Yang Y, Jiang S, Ye M, Chen H, Diao W, Xu S
Phytotherapy research : PTR 2023 Sep;37(9):4059-4075

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Isoamericanin A improves lipopolysaccharide-induced memory impairment in mice through suppression of the nicotinamide adenine dinucleotide phosphateoxidase-dependent nuclear factor kappa B signaling pathway.

Yang Y, Chen R, Che Y, Yao X, Fang M, Wang Y, Zhou D, Li N, Hou Y
Phytotherapy research : PTR 2023 Sep;37(9):3982-4001

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LINC00938 alleviates hypoxia ischemia encephalopathy induced neonatal brain injury by regulating oxidative stress and inhibiting JNK/p38 MAPK signaling pathway.

Zhao J, Le M, Li J, Huang Q, Chen H, Zhang W, Mao H, Sun Q, Li A, Zhao Y, Yu L, Yi M, Wang J, Li X, Zhang G, Ma J, Dong X
Experimental neurology 2023 Sep;367:114449

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Silibinin ameliorates deoxycholic acid-induced pyroptosis in steatotic HepG2 cells by inhibiting NLRP3 inflammasome activation.

Mai M, Wang Y, Luo M, Li Z, Wang D, Ruan Y, Guo H
Biochemistry and biophysics reports 2023 Sep;35:101545

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CHAF1A promotes the proliferation and growth of epithelial ovarian cancer cells by affecting the phosphorylation of JAK2/STAT3 signaling pathway.

Xia D, Xu X, Wei J, Wang W, Xiong J, Tan Q, Xue P, Wang H
Biochemistry and biophysics reports 2023 Sep;35:101522

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Lysine methylation of PPP1CA by the methyltransferase SUV39H2 disrupts TFEB-dependent autophagy and promotes intervertebral disc degeneration.

Liang H, Luo R, Li G, Zhang W, Zhu D, Wu D, Zhou X, Tong B, Wang B, Feng X, Wang K, Song Y, Yang C
Cell death and differentiation 2023 Sep;30(9):2135-2150

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Porcine reproductive and respiratory syndrome virus-mediated lactate facilitates virus replication by targeting MAVS.

Zhang L, Liu X, Mao J, Sun Y, Gao Y, Bai J, Jiang P
Veterinary microbiology 2023 Sep;284:109846

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PEDV N protein capture protein translation element PABPC1 and eIF4F to promote viral replication.

Zhai H, Qin W, Dong S, Yang X, Zhai X, Tong W, Liu C, Zheng H, Yu H, Kong N, Tong G, Shan T
Veterinary microbiology 2023 Sep;284:109844

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PRRSV inhibited the proliferation of CSFV by inducing IL-1β maturation via NLRP3 inflammasome activation.

Chen D, Tuo T, Zhang Y, Zhou L, Ge X, Han J, Guo X, Yang H
Veterinary microbiology 2023 Sep;284:109825

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Relief of gouty arthritis in rats by total saponins from Dioscorea nipponica Makino through suppression of neutrophil extracellular trap formation via the PI3K/AKT/mTOR axis.

Zhou Q, Liu L, Sun H, Liu S
Experimental and therapeutic medicine 2023 Sep;26(3):447

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Tetracaine hydrochloride induces macrophage pyroptosis through caspase‑1/11‑GSDMD signaling pathways.

Zhang R, Gou W, Yi P, Qin Z, Zhu D, Jia J, Liu L, Jiang X, Feng J
Experimental and therapeutic medicine 2023 Sep;26(3):428

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Antisense lncRNA-RP11-498C9.13 promotes bladder cancer progression by enhancing reactive oxygen species-induced mitophagy.

Song W, Li Z, Yang K, Gao Z, Zhou Q, Li P
The journal of gene medicine 2023 Sep;25(9):e3527

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Knockdown of AK142426 suppresses M2 macrophage polarization and inflammation in peritoneal fibrosis via binding to c-Jun.

Shao Q, Jiang C, Zhang Q, Liu J, Jin B, Zhao M, Xia Y
The journal of gene medicine 2023 Sep;25(9):e3524

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Whether the Subacute MPTP-Treated Mouse is as Suitable as a Classic Model of Parkinsonism.

Qi Y, Zhang Z, Li Y, Zhao G, Huang J, Zhang Y, Xue J, Tang X
Neuromolecular medicine 2023 Sep;25(3):360-374

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Glutaredoxin 2 protects lens epithelial cells from epithelial-mesenchymal transition by suppressing mitochondrial oxidative stress-related upregulation of integrin-linked kinase.

Chen X, Chen Y, Li C, Li J, Zhang S, Liang C, Deng Q, Guo Z, Guo C, Yan H
Experimental eye research 2023 Sep;234:109609

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The long noncoding RNA CIRBIL is a regulator of steroidogenesis in mice.

Huang X, Liu X, Zhang X, Yang Y, Gao H, Gao J, Bao H, Zhao L, Yang G, Zhang Y, Liu D
Reproductive biology 2023 Sep;23(3):100783

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EIF4A3-regulated hsa_circ_0001445 can inhibit the progression of laryngeal squamous cell carcinoma via hsa-miR-432-5p-dependent up-regulation of RGMA expression.

Yu M, Cao H, Yang J, Liu T, Gao J, Wang B
Cell cycle (Georgetown, Tex.) 2023 Sep;22(18):2038-2056

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Hypoxia-induced GPCPD1 depalmitoylation triggers mitophagy via regulating PRKN-mediated ubiquitination of VDAC1.

Liu Y, Zhang H, Liu Y, Zhang S, Su P, Wang L, Li Y, Liang Y, Wang X, Zhao W, Chen B, Luo D, Zhang N, Yang Q
Autophagy 2023 Sep;19(9):2443-2463

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Heat shock factor 1 promotes neurite outgrowth and suppresses inflammation in the severed spinal cord of geckos.

He BQ, Li AC, Hou YX, Li H, Zhang XY, Hao HF, Song HH, Cai RX, Wang YJ, Zhou Y, Wang YJ
Neural regeneration research 2023 Sep;18(9):2011-2018

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TRAF6-TAK1-IKKβ pathway mediates TLR2 agonists activating "one-step" NLRP3 inflammasome in human monocytes.

Chen M, Yu S, Gao Y, Li J, Wang X, Wei B, Meng G
Cytokine 2023 Sep;169:156302

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The 5-HT(7) receptors in the VLO contribute to the development of morphine-induced behavioral sensitization in rats.

Yang JS, Gao FF, Yang XX, Liang F, Yang ZJ, Chen J, Zhang YX, Yan CX
Neurochemistry international 2023 Sep;168:105566

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Analysis of gene expression profiles and experimental validations of a rat chronic cervical cord compression model.

Pu PM, Li ZY, Dai YX, Sun YL, Wang YJ, Cui XJ, Yao M
Neurochemistry international 2023 Sep;168:105564

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The mechanism of metformin combined with total flavonoids of Rhizoma Drynariae on ovariectomy-induced osteoporotic rats.

Jiang N, Jin H, Yang K, Zhang Z, Xu W, Chen X, Zhang Z, Xu H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115181

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PFKFB2 is a favorable prognostic biomarker for colorectal cancer by suppressing metastasis and tumor glycolysis.

Liu F, Wei X, Chen Z, Chen Y, Hu P, Jin Y
Journal of cancer research and clinical oncology 2023 Sep;149(12):10737-10752

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USP2 promotes cell proliferation and metastasis in choroidal melanoma via stabilizing Snail.

Wei C, Zhao X, Zhang H, Wang L
Journal of cancer research and clinical oncology 2023 Sep;149(11):9263-9276

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In vitro and in vivo study on the treatment of non-small cell lung cancer with radionuclide labeled PD-L1 nanobody.

Zhu M, Zhang J, Yang M, Zhang H, Xu T, Kan F, Zhang X, Zhang S, Yin Y, Yu F
Journal of cancer research and clinical oncology 2023 Sep;149(11):8429-8442

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The kinase inhibitory region of SOCS3 attenuates reactive astrogliosis and astroglial scar in mice after traumatic brain injury.

Cai Z, Zhang Z, Zhang L, Tan R, Wang Y, Sun M, Hu X, Ge Q, An J, Lu H
Journal of chemical neuroanatomy 2023 Sep;131:102273

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IGF2BP3 mediates the mRNA degradation of NF1 to promote triple-negative breast cancer progression via an m6A-dependent manner.

Zhang X, Shi L, Sun HD, Wang ZW, Xu F, Wei JF, Ding Q
Clinical and translational medicine 2023 Sep;13(9):e1427

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Circular RNA circARPC1B functions as a stabilisation enhancer of Vimentin to prevent high cholesterol-induced articular cartilage degeneration.

Li J, Li X, Zhou S, Wang Y, Ying T, Wang Q, Wu Y, Zhao F
Clinical and translational medicine 2023 Sep;13(9):e1415

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ACSL4 promotes ferroptosis and M1 macrophage polarization to regulate the tumorigenesis of nasopharyngeal carcinoma.

Chen P, Wang D, Xiao T, Gu W, Yang H, Yang M, Wang H
International immunopharmacology 2023 Sep;122:110629

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Pharmacological activation of the Nrf2 pathway by Taxifolin remodels articular cartilage microenvironment for the therapy of Osteoarthritis.

Jiang H, Yu J, Yan Z, Lin Z, Lin M, Mao Y, Hong Z, Lin J, Xue X, Pan X
International immunopharmacology 2023 Sep;122:110587

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CD73 inhibits titanium particle-associated aseptic loosening by alternating activation of macrophages.

Sun Z, Kang J, Yang S, Zhang Y, Huang N, Zhang X, Du G, Jiang J, Ning B
International immunopharmacology 2023 Sep;122:110561

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Lunasin reduces the susceptibility of IL-10 deficient mice to inflammatory bowel disease and modulates the activation of the NLRP3 inflammasome.

Nieto-Veloza A, Hong S, Reeder M, Sula MJ, D'Souza DH, Zhong Q, Dia VP
The Journal of nutritional biochemistry 2023 Sep;119:109383

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Comparison of endocytosis pathways of Duck Tembusu virus in BHK-21 and duck embryo fibroblasts.

Xian X, Yang S, Shi Y, Chen Q
Poultry science 2023 Sep;102(9):102891

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miR-146b-5p promotes duck Tembusu virus replication by targeting RPS14.

Huang J, Lei L, Cui M, Cheng A, Wang M, Liu M, Zhu D, Chen S, Zhao X, Yang Q, Wu Y, Zhang S, Ou X, Mao S, Gao Q, Sun D, Tian B, Yin Z, Jia R
Poultry science 2023 Sep;102(9):102890

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Targeted knockout of Mx in the DF-1 chicken fibroblast cell line impairs immune response against Newcastle disease virus.

Wang L, Xue Z, Wang J, Jian Y, Lu H, Ma H, Wang S, Zeng W, Zhang T
Poultry science 2023 Sep;102(9):102855

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TP53RK Drives the Progression of Chronic Kidney Disease by Phosphorylating Birc5.

Wu M, Jin Q, Xu X, Fan J, Chen W, Miao M, Gu R, Zhang S, Guo Y, Huang S, Zhang Y, Zhang A, Jia Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(25):e2301753

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Estrogen-Induced LncRNA, LINC02568, Promotes Estrogen Receptor-Positive Breast Cancer Development and Drug Resistance Through Both In Trans and In Cis Mechanisms.

Chen X, Ding JC, Hu GS, Shu XY, Liu Y, Du J, Wen ZJ, Liu JY, Huang HH, Tang GH, Liu W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(25):e2206663

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Ochratoxin A induces abnormal tryptophan metabolism in the intestine and liver to activate AMPK signaling pathway.

Ma W, Fu Y, Zhu S, Xia D, Zhai S, Xiao D, Zhu Y, Dione M, Ben L, Yang L, Wang W
Journal of animal science and biotechnology 2023 Sep 8;14(1):125

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Gut microbes exacerbate systemic inflammation and behavior disorders in neurologic disease CADASIL.

Liu S, Men X, Guo Y, Cai W, Wu R, Gao R, Zhong W, Guo H, Ruan H, Chou S, Mai J, Ping S, Jiang C, Zhou H, Mou X, Zhao W, Lu Z
Microbiome 2023 Sep 8;11(1):202

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Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation.

Wang J, Xie W, Li N, Li W, Zhang Z, Fan N, Ouyang Z, Zhao Y, Lai C, Li H, Chen M, Quan L, Li Y, Jiang Y, Jia W, Fu L, Mazid MA, Zhu Y, Maxwell PH, Pan G, Esteban MA, Dai Z, Lai L
Cell stem cell 2023 Sep 7;30(9):1235-1245.e6

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SUMO1-regulated DBC1 promotes p53-dependent stress-induced apoptosis of lens epithelial cells.

Wang Y, Wang JM, Xiao Y, Hu XB, Zheng SY, Fu JL, Zhang L, Gan YW, Liang XM, Li DW
Aging 2023 Sep 7;15(17):8812-8832

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Asarinin attenuates bleomycin-induced pulmonary fibrosis by activating PPARγ.

Zeng Q, Zhou TT, Huang WJ, Huang XT, Huang L, Zhang XH, Sang XX, Luo YY, Tian YM, Wu B, Liu L, Luo ZQ, He B, Liu W, Tang SY
Scientific reports 2023 Sep 7;13(1):14706

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Reduced expression of phosphorylated ataxia-telangiectasia mutated gene is related to poor prognosis and gemcitabine chemoresistance in pancreatic cancer.

Xun J, Ohtsuka H, Hirose K, Douchi D, Nakayama S, Ishida M, Miura T, Ariake K, Mizuma M, Nakagawa K, Morikawa T, Furukawa T, Unno M
BMC cancer 2023 Sep 6;23(1):835

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A novel small molecule effectively ameliorates estrogen deficiency-induced osteoporosis by targeting the gut-bone signaling axis.

Chen C, Lei H, Zhao Y, Hou Y, Zheng H, Zhang C, Cao Z, Wu F, Chen G, Song Y, Zhang C, Zhou J, Lu Y, Xie D, Zhang L
European journal of pharmacology 2023 Sep 5;954:175868

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1,8-Cineole ameliorates endothelial injury and hypertension induced by L-NAME through regulation of autophagy via PI3K/mTOR signaling pathway.

Chen M, Hu Q, Wang S, Tao L, Hu X, Shen X
European journal of pharmacology 2023 Sep 5;954:175863

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Activation of TrkB signaling mitigates cerebellar anomalies caused by Rbm4-Bdnf deficiency.

Tsai YY, Shen CL, D D, Tsai CY, Tarn WY
Communications biology 2023 Sep 5;6(1):910

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Structural characterization of human RPA70N association with DNA damage response proteins.

Wu Y, Fu W, Zang N, Zhou C
eLife 2023 Sep 5;12

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A twin UGUA motif directs the balance between gene isoforms through CFIm and the mTORC1 signaling pathway.

Herron RS, Kunisky AK, Madden JR, Anyaeche VI, Maung MZ, Hwang HW
eLife 2023 Sep 4;12

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Preparation of a new resource food-arabinogalactan and its protective effect against enterotoxicity in IEC-6 cells by inhibiting endoplasmic reticulum stress.

Zhang S, Wang S, Fan YY, Liu WC, Zheng YN, Wang Z, Ren S, Li W
International journal of biological macromolecules 2023 Sep 30;249:126124

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A multifunctional polydopamine/genipin/alendronate nanoparticle licences fibrin hydrogels osteoinductive and immunomodulatory potencies for repairing bone defects.

Shi W, Gao Y, Wu Y, Sun J, Xu B, Lu X, Wang Q
International journal of biological macromolecules 2023 Sep 30;249:126072

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miR-491-5p regulates the susceptibility of glioblastoma to ferroptosis through TP53.

Jie XF, Li YP, Liu S, Fu Y, Xiong YY
Biochemical and biophysical research communications 2023 Sep 3;671:309-317

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Hesperidin inhibits methylation and autophagy in LPS and high glucose-induced human villous trophoblasts.

Chen Q, Hu K, Shi J, Li H, Li W
Biochemical and biophysical research communications 2023 Sep 3;671:278-285

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Gastrodin relieves cognitive impairment by regulating autophagy via PI3K/AKT signaling pathway in vascular dementia.

Chen YX, Yang H, Wang DS, Yao YT, Chen TT, Tao L, Chen Y, Shen XC
Biochemical and biophysical research communications 2023 Sep 3;671:246-254

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Antidiabetic Effect of Collagen Peptides from Harpadon nehereus Bones in Streptozotocin-Induced Diabetes Mice by Regulating Oxidative Stress and Glucose Metabolism.

Lin Q, Guo Y, Li J, He S, Chen Y, Jin H
Marine drugs 2023 Sep 29;21(10)

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HSP90B1-mediated plasma membrane localization of GLUT1 promotes radioresistance of glioblastomas.

Li Y, Ge Y, Zhao M, Ding F, Wang X, Shi Z, Ge X, Wang X, Qian X
Journal of biomedical research 2023 Sep 28;37(5):326-339

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The Gut Microbiota of Pregnant Rats Alleviates Fetal Growth Restriction by Inhibiting the TLR9/MyD88 Pathway.

Tang H, Li H, Li D, Peng J, Zhang X, Yang W
Journal of microbiology and biotechnology 2023 Sep 28;33(9):1213-1227

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Benzophenanthridine Alkaloid Chelerythrine Elicits Necroptosis of Gastric Cancer Cells via Selective Conjugation at the Redox Hyperreactive C-Terminal Sec(498) Residue of Cytosolic Selenoprotein Thioredoxin Reductase.

Liu M, Sun S, Meng Y, Wang L, Liu H, Shi W, Zhang Q, Xu W, Sun B, Xu J
Molecules (Basel, Switzerland) 2023 Sep 28;28(19)

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PUF60 promotes cell cycle and lung cancer progression by regulating alternative splicing of CDC25C.

Xu N, Ren Y, Bao Y, Shen X, Kang J, Wang N, Wang Z, Han X, Li Z, Zuo J, Wei GH, Wang Z, Zong WX, Liu W, Xie G, Wang Y
Cell reports 2023 Sep 26;42(9):113041

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PM2.5 leads to adverse pregnancy outcomes by inducing trophoblast oxidative stress and mitochondrial apoptosis via KLF9/CYP1A1 transcriptional axis.

Li S, Li L, Zhang C, Fu H, Yu S, Zhou M, Guo J, Fang Z, Li A, Zhao M, Zhang M, Wang X
eLife 2023 Sep 22;12

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TSWIFT, a novel method for iterative staining of embedded and mounted human brain sections.

Porter CM, Truttmann MC
bioRxiv : the preprint server for biology 2023 Sep 22;

---

Glucose Starvation Stimulates the Promoting Strength of a Novel Evolved Suc2 Promoter.

Wang B, Zhao X, Fu T, Chen X, Guo X, Li X, Yang F
Journal of agricultural and food chemistry 2023 Sep 20;71(37):13838-13847

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[miRNA-128-3p inhibits malignant behavior of glioma cells by downregulating KLHDC8A expression].

Yu Z, Li J, Jiang J, Li Y, Lin L, Xia Y, Wang L
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Sep 20;43(9):1447-1459

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A Unique G-Quadruplex Aptamer: A Novel Approach for Cancer Cell Recognition, Cell Membrane Visualization, and RSV Infection Detection.

Xiao CD, Zhong MQ, Gao Y, Yang ZL, Jia MH, Hu XH, Xu Y, Shen XC
International journal of molecular sciences 2023 Sep 20;24(18)

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Icariin-Curcumol promotes docetaxel sensitivity in prostate cancer through modulation of the PI3K-Akt signaling pathway and the Warburg effect.

Xu W, Ding J, Kuang S, Li B, Sun T, Zhu C, Liu J, Zhu L, Li Y, Sheng W
Cancer cell international 2023 Sep 2;23(1):190

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Lactobacillus fermentum Alleviates the Colorectal Inflammation Induced by Low-Dose Sub-Chronic Microcystin-LR Exposure.

Yang Y, Wen C, Zheng S, Song F, Liu Y, Yao X, Tang Y, Feng X, Chen J, Yang F
Toxins 2023 Sep 19;15(9)

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Long-Term Exposure to Microcystin-LR Induces Gastric Toxicity by Activating the Mitogen-Activated Protein Kinase Signaling Pathway.

Liu Y, Li Y, Tan Q, Lv Y, Tang Y, Yang Y, Yao X, Yang F
Toxins 2023 Sep 18;15(9)

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Rosmarinic acid ameliorates autoimmune responses through suppression of intracellular nucleic acid-mediated type I interferon expression.

Li XW, Yuan SC, Wang M, Su ZH, Zhao M, Li T, Zhang XM, Xue W, Li WH
Biochemical and biophysical research communications 2023 Sep 17;673:73-80

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Specific inhibitory effects of guanosine on breast cancer cell proliferation.

Takizawa Y, Kizawa M, Niwa N, Komura Y, Takahashi M, Koda D, Kurita T, Nakajima T
Biochemical and biophysical research communications 2023 Sep 17;673:67-72

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Hypoxic Preconditioning Enhances Cellular Viability and Migratory Ability: Role of DANCR/miR-656-3p/HIF-1α Axis in Placental Mesenchymal Stem Cells.

Haoran S, Zhishan J, Yan M, Ruilin M, Jianjian C, Zejun Y, Jianwen Z, Hui G, Yin Z
Stem cells (Dayton, Ohio) 2023 Sep 15;41(9):877-891

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Ginsenoside Rg1 attenuates diabetic vascular endothelial dysfunction by inhibiting the calpain-1/ROS/PKC-β axis.

Lu M, Zhao F, Ran C, Xu Y, Zhang J, Wang H
Life sciences 2023 Sep 15;329:121972

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Modified Gegen Qinlian decoction ameliorated ulcerative colitis by attenuating inflammation and oxidative stress and enhancing intestinal barrier function in vivo and in vitro.

Wang Y, Zhang J, Zhang B, Lu M, Ma J, Liu Z, Huang J, Ma J, Yang X, Wang F, Tang X
Journal of ethnopharmacology 2023 Sep 15;313:116538

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Congenital cataracts affect the retinal visual cycle and mitochondrial function: A multi-omics study of GJA8 knockout rabbits.

Sun W, Gu S, Zhang F, Xu M, Chang P, Zhao Y
Journal of proteomics 2023 Sep 15;287:104972

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ATG7 upregulation contributes to malignant transformation of human bronchial epithelial cells by B[a]PDE via DNMT3B protein degradation and miR-494 promoter methylation.

Tian Z, Hua X, Zhu J, Li P, Chen R, Li X, Li T, Zhou C, Huang C
Ecotoxicology and environmental safety 2023 Sep 15;263:115273

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Cadmium exposure promotes ferroptosis by upregulating Heat Shock Protein 70 in vascular endothelial damage of zebrafish.

Zhang T, Yan W, Liu C, Duan W, Duan Y, Li Y, Yu Q, Sun Y, Tian J, Zhou J, Xia Z, Wang G, Xu S
Ecotoxicology and environmental safety 2023 Sep 15;263:115241

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A stepwise and digital pattern of RSK phosphorylation determines the outcome of thymic selection.

Funasaki S, Hatano A, Nakatsumi H, Koga D, Sugahara O, Yumimoto K, Baba M, Matsumoto M, Nakayama KI
iScience 2023 Sep 15;26(9):107552

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Systemic gene therapy using an AAV44.9 vector rescues a neonatal lethal mouse model of propionic acidemia.

Chandler RJ, Di Pasquale G, Choi EY, Chang D, Smith SN, Sloan JL, Hoffmann V, Li L, Chiorini JA, Venditti CP
Molecular therapy. Methods & clinical development 2023 Sep 14;30:181-190

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Solar ultraviolet B radiation promotes α-MSH secretion to attenuate the function of ILC2s via the pituitary-lung axis.

Huang Y, Zhu L, Cheng S, Dai R, Huang C, Song Y, Peng B, Li X, Wen J, Gong Y, Hu Y, Qian L, Zhu L, Zhang F, Yu L, Yi C, Gu W, Ling Z, Ma L, Tang W, Peng L, Shi G, Zhang Y, Sun B
Nature communications 2023 Sep 12;14(1):5601

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Codium fragile Suppressed Chronic PM(2.5)-Exposed Pulmonary Dysfunction via TLR/TGF-β Pathway in BALB/c Mice.

Kim TY, Kim JM, Lee HL, Go MJ, Joo SG, Kim JH, Lee HS, Jeong WM, Lee DY, Kim HJ, Heo HJ
Antioxidants (Basel, Switzerland) 2023 Sep 10;12(9)

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Long-term iTBS Improves Neural Functional Recovery by Reducing the Inflammatory Response and Inhibiting Neuronal Apoptosis Via miR-34c-5p/p53/Bax Signaling Pathway in Cerebral Ischemic Rats.

Hu S, Wang X, Yang X, Ouyang S, Pan X, Fu Y, Wu S
Neuroscience 2023 Sep 1;527:37-51

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Gambogenic acid induces cell death in human osteosarcoma through altering iron metabolism, disturbing the redox balance, and activating the P53 signaling pathway.

Liu Z, Wang X, Li J, Yang X, Huang J, Ji C, Li X, Li L, Zhou J, Hu Y
Chemico-biological interactions 2023 Sep 1;382:110602

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Epithelial TIPE1 Protein Guards against Colitis by Inhibiting TNF-α-Mediated Inflammation.

Lou Y, Jiang S, Song M, Wang H, Han M, Tian X, Zhao Y, Gao J, Song Y, Ma S, Zhao P, Zheng Q, Niu Z, Zhang W, Chang T, Chen YH, Wang H
Journal of immunology (Baltimore, Md. : 1950) 2023 Sep 1;211(5):874-884

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Carbon Ions Suppress Angiogenesis and Lung Metastases in Melanoma by Targeting CXCL10.

Li C, Zhang Q, Luo H, Liu R, Feng S, Geng Y, Wang L, Yang Z, Zhang Y, Wang X
Radiation research 2023 Sep 1;200(3):307-319

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TGR5 supresses cGAS/STING pathway by inhibiting GRP75-mediated endoplasmic reticulum-mitochondrial coupling in diabetic retinopathy.

Li Y, Zhu L, Cai MX, Wang ZL, Zhuang M, Tan CY, Xie TH, Yao Y, Wei TT
Cell death & disease 2023 Sep 1;14(9):583

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SAP30 promotes breast tumor progression by bridging the transcriptional corepressor SIN3 complex and MLL1.

Bao L, Kumar A, Zhu M, Peng Y, Xing C, Wang JE, Wang Y, Luo W
The Journal of clinical investigation 2023 Sep 1;133(17)

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DSTN Hypomethylation Promotes Radiotherapy Resistance of Rectal Cancer by Activating the Wnt/β-Catenin Signaling Pathway.

Wen R, Zhou L, Jiang S, Fan H, Zheng K, Yu Y, Gao X, Hao L, Lou Z, Yu G, Yang F, Zhang W
International journal of radiation oncology, biology, physics 2023 Sep 1;117(1):198-210

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RBM15‑mediating MDR1 mRNA m(6)A methylation regulated by the TGF‑β signaling pathway in paclitaxel‑resistant ovarian cancer.

Yuan J, Guan W, Li X, Wang F, Liu H, Xu G
International journal of oncology 2023 Oct;63(4)

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Ghrelin inhibits NLRP3 inflammasome activation by upregulating autophagy to improve Alzheimer's disease.

Guo Y, Zhang L
In vitro cellular & developmental biology. Animal 2023 Oct;59(9):665-673

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Quercetin promotes autophagy to alleviate cigarette smoke-related periodontitis.

Yu J, Jing Z, Shen D, Yang M, Liu K, Xiang K, Zhou C, Gong X, Deng Y, Li Y, Yang S
Journal of periodontal research 2023 Oct;58(5):1082-1095

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Molecular classification of hormone receptor-positive HER2-negative breast cancer.

Jin X, Zhou YF, Ma D, Zhao S, Lin CJ, Xiao Y, Fu T, Liu CL, Chen YY, Xiao WX, Liu YQ, Chen QW, Yu Y, Shi LM, Shi JX, Huang W, Robertson JFR, Jiang YZ, Shao ZM
Nature genetics 2023 Oct;55(10):1696-1708

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Fine particulate matter promotes airway inflammation and mucin production by activating endoplasmic reticulum stress and the IRE1α/NOD1/NF‑κB pathway.

Hu L, Xu C, Tang X, Yu S, Wang L, Li Q, Zhou X
International journal of molecular medicine 2023 Oct;52(4)

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Loss of hepatic FTCD promotes lipid accumulation and hepatocarcinogenesis by upregulating PPARγ and SREBP2.

Wang S, Zhou Y, Yu R, Ling J, Li B, Yang C, Cheng Z, Qian R, Lin Z, Yu C, Zheng J, Zheng X, Jia Q, Wu W, Wu Q, Chen M, Yuan S, Dong W, Shi Y, Jansen R, Yang C, Hao Y, Yao M, Qin W, Jin H
JHEP reports : innovation in hepatology 2023 Oct;5(10):100843

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IGF-1 Combined with OPN Promotes Neuronal Axon Growth in Vitro Through the IGF-1R/Akt/mTOR Signaling Pathway in Lipid Rafts.

Zhao Q, Su H, Jiang W, Luo H, Pan L, Liu Y, Yang C, Yin Y, Yu L, Tan B
Neurochemical research 2023 Oct;48(10):3190-3201

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VCAM-1(+) hUC-MSCs Exert Considerable Neuroprotection Against Cerebral Infarction in Rats by Suppression of NLRP3-Induced Pyroptosis.

Zhang X, Sang X, Chen Y, Yu H, Sun Y, Liang X, Zheng X, Wang X, Yang H, Bi J, Zhang L, Wang P
Neurochemical research 2023 Oct;48(10):3084-3098

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Pregnane X receptor activation alleviates renal fibrosis in mice via interacting with p53 and inhibiting the Wnt7a/β-catenin signaling.

Ming WH, Luan ZL, Yao Y, Liu HC, Hu SY, Du CX, Zhang C, Zhao YH, Huang YZ, Sun XW, Qiao RF, Xu H, Guan YF, Zhang XY
Acta pharmacologica Sinica 2023 Oct;44(10):2075-2090

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miR-188-5p silencing improves cerebral ischemia/reperfusion injury by targeting Lin28a.

Hou D, Pei C, Yu D, Yang G
Metabolic brain disease 2023 Oct;38(7):2327-2338

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The potential mechanism of Choulingdan mixture in improving acute lung injury based on HPLC-Q-TOF-MS, network pharmacology and in vivo experiments.

Wang L, Li Z, Lu T, Su L, Mao C, Zhang Y, Zhang X, Jiang X, Xie H, Yu X
Biomedical chromatography : BMC 2023 Oct;37(10):e5709

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Bavachinin selectively modulates PPAR γ and maintains bone homeostasis in Type 2 Diabetes.

Liu J, Li X, Wang H, Ren Y, Li Y, Guo F
Phytotherapy research : PTR 2023 Oct;37(10):4457-4472

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Paternal cadmium exposure induces glucolipid metabolic reprogramming in offspring mice via PPAR signaling pathway.

Zeng L, Zhou J, Zhang Y, Wang X, Li Y, Song J, Shao J, Su P
Chemosphere 2023 Oct;339:139592

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BCKDHA contributes to melanoma progression by promoting the expressions of lipogenic enzymes FASN and ACLY.

Tian Y, Ma J, Wang M, Yi X, Guo S, Wang H, Zhang H, Wang H, Yang Y, Zhang B, Du J, Shi Q, Gao T, Li C, Guo W
Experimental dermatology 2023 Oct;32(10):1633-1643

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Filamin A facilitates NLRP3 inflammasome activation during arsenic-induced nonalcoholic steatohepatitis.

Shi Y, Qiu T, Wu C, Yuan W, Yao X, Jiang L, Wang N, Wang L, Han Q, Yang G, Liu X, Sun X
Environmental science and pollution research international 2023 Oct;30(49):107703-107715

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The E3 ubiquitin ligase TRIM17 promotes gastric cancer survival and progression via controlling BAX stability and antagonizing apoptosis.

Shen J, Yang H, Qiao X, Chen Y, Zheng L, Lin J, Lang J, Yu Q, Wang Z
Cell death and differentiation 2023 Oct;30(10):2322-2335

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LncRNA BCAN-AS1 stabilizes c-Myc via N(6)-methyladenosine-mediated binding with SNIP1 to promote pancreatic cancer.

Wu G, Su J, Zeng L, Deng S, Huang X, Ye Y, Li R, Bai R, Zhuang L, Li M, Zhou Q, Zheng Y, Deng J, Zhang S, Chen R, Lin D, Zhang J, Zheng J
Cell death and differentiation 2023 Oct;30(10):2213-2230

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DJ-1-mediated p62 degradation delays intervertebral disc degeneration by inhibiting apoptosis of nucleus pulposus cells.

Lin J, Zheng X, Xiong Z, Xiang Q, Zhao Y, Jiang S, Sun Z, Fan D, Sun C, Li W
Apoptosis : an international journal on programmed cell death 2023 Oct;28(9-10):1357-1371

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Oncogenic roles of GPR176 in breast cancer: a potential marker of aggressiveness and a potential target of gene therapy.

Yun WJ, Xue H, Yang N, Xiao LJ, Sun HZ, Zheng HC
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 Oct;25(10):3042-3056

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CRISPR/SaCas9-based gene editing rescues photoreceptor degeneration throughout a rhodopsin-associated autosomal dominant retinitis pigmentosa mouse model.

Du W, Li J, Tang X, Yu W, Zhao M
Experimental biology and medicine (Maywood, N.J.) 2023 Oct;248(20):1818-1828

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Functional analysis of two abnormal antithrombin proteins with different intracellular kinetics.

Imai Y, Nagaya S, Araiso Y, Meguro-Horike M, Togashi T, Horike SI, Kawasaki H, Morishita E
Thrombosis research 2023 Oct;230:18-26

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ACLY promotes gastric tumorigenesis and accelerates peritoneal metastasis of gastric cancer regulated by HIF-1A.

Yan Z, Liu K, Xu P, Chen Z, Zhang P, Pei S, Cheng Q, Huang S, Li B, Lv J, Xu Z, Xu H, Yang L, Zhang D
Cell cycle (Georgetown, Tex.) 2023 Oct;22(20):2288-2301

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IGF2BP2 promotes glycolysis and hepatocellular carcinoma stemness by stabilizing CDC45 mRNA via m6A modification.

Wu T, Liao L, Wu T, Chen S, Yi Q, Xu M
Cell cycle (Georgetown, Tex.) 2023 Oct;22(20):2245-2263

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EGFR suppression contributes to growth inhibitory activity of G-quadruplex ligands in non-small cell lung cancers.

Lu K, Wang HC, Tu YC, Lou PJ, Chang TC, Lin JJ
Biochemical pharmacology 2023 Oct;216:115788

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Histone methyltransferase SETD2 inhibits M1 macrophage polarization and glycolysis by suppressing HIF-1α in sepsis-induced acute lung injury.

Meng Y, Kong KW, Chang YQ, Deng XM, Yang T
Medical microbiology and immunology 2023 Oct;212(5):369-379

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FN1 mediated activation of aspartate metabolism promotes the progression of triple-negative and luminal a breast cancer.

Chen C, Ye L, Yi J, Liu T, Li Z
Breast cancer research and treatment 2023 Oct;201(3):515-533

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A sequential scheme including PTT and 2'3'-cGAMP/CQ-LP reveals the antitumor immune function of PTT through the type I interferon pathway.

Song X, Wang M, Liu S, Liu H, Jiang A, Zou Y, Deng Y, Qin Q, Song Y, Zheng Y
Pharmacological research 2023 Oct;196:106939

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Ampelopsin attenuates Staphylococcus aureus Alpha-Toxin-Induced Lung Injury.

Wang Y, Tang M, Deng H, Hong Z, Liang Z, Huang Y, Zeng C, Yang K
Microbial pathogenesis 2023 Oct;183:106316

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Activation of Nrf2 signalling pathway by tectoridin protects against ferroptosis in particulate matter-induced lung injury.

Dong T, Fan X, Zheng N, Yan K, Hou T, Peng L, Ci X
British journal of pharmacology 2023 Oct;180(19):2532-2549

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6-Mercaptopurine potently inhibits recruitment of SHP2 by phosphorylated PD-1 to inhibit PD-1 signalling and enhance T cell function.

Liu L, Lei Y, Zheng Z, Zhou X, Chen S, Zeng G, Yu L, Wang P, Chen L
Immunology 2023 Oct;170(2):230-242

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The role of the gut-microbiota-brain axis via the subdiaphragmatic vagus nerve in chronic inflammatory pain and comorbid spatial working memory impairment in complete Freund's adjuvant mice.

Yue C, Luan W, Gu H, Qiu D, Ding X, Liu P, Wang X, Hashimoto K, Yang JJ
Journal of psychiatric research 2023 Oct;166:61-73

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Babao Dan alleviates gut immune and microbiota disorders while impacting the TLR4/MyD88/NF-кB pathway to attenuate 5-Fluorouracil-induced intestinal injury.

Huang B, Gui M, An H, Shen J, Ye F, Ni Z, Zhan H, Che L, Lai Z, Zeng J, Peng J, Lin J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115387

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Undesirable ER stress induced by bavachin contributed to follicular atresia in zebrafish ovary.

Huang CS, Deng HF, Zhou L, Shen P, Ni YH, Wang NN, Li GF, Yue LX, Zhou YQ, Zhou W, Gao Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115322

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Synthesis and biological evaluation of chromanone-based derivatives as potential anti-neuroinflammatory agents.

Li G, Feng X, Wang W, Li J, Shi Y, Wang L, Hu C
Bioorganic chemistry 2023 Oct;139:106767

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Cullin-associated and neddylation-dissociated 1 regulate reprogramming of lipid metabolism through SKP1-Cullin-1-F-box(FBXO11) -mediated heterogeneous nuclear ribonucleoprotein A2/B1 ubiquitination and promote hepatocellular carcinoma.

Zhang H, Xia P, Yang Z, Liu J, Zhu Y, Huang Z, Zhang Z, Yuan Y
Clinical and translational medicine 2023 Oct;13(10):e1443

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Quercetin ameliorates nonalcoholic fatty liver disease (NAFLD) via the promotion of AMPK-mediated hepatic mitophagy.

Cao P, Wang Y, Zhang C, Sullivan MA, Chen W, Jing X, Yu H, Li F, Wang Q, Zhou Z, Wang Q, Tian W, Qiu Z, Luo L
The Journal of nutritional biochemistry 2023 Oct;120:109414

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Anti-rheumatoid arthritis effects of total saponins from Rhizoma Panacis Majoris on adjuvant-induced arthritis in rats and rheumatoid arthritis fibroblast-like synoviocytes.

Ren M, Ma K, Pang X, Liu Y, Song Z, Zhou R, Tang Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155021

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OTUB1's role in promoting OSCC development by stabilizing RACK1 involves cell proliferation, migration, invasion, and tumor-associated macrophage M1 polarization.

Li Y, Li R, Qin H, He H, Li S
Cellular signalling 2023 Oct;110:110835

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Puerarin protects against acetaminophen-induced oxidative damage in liver through activation of the Keap1/Nrf2 signaling pathway.

Zhou W, He H, Wei Q, Che L, Zhao X, Liu W, Yan Y, Hu L, Du Y, Yin Z, Shuai Y, Yang L, Feng R
Food science & nutrition 2023 Oct;11(10):6604-6615

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CCDC50 promotes tumor growth through regulation of lysosome homeostasis.

Jia P, Tian T, Li Z, Wang Y, Lin Y, Zeng W, Ye Y, He M, Ni X, Pan J, Dong X, Huang J, Li CM, Guo D, Hou P
EMBO reports 2023 Oct 9;24(10):e56948

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URI alleviates tyrosine kinase inhibitors-induced ferroptosis by reprogramming lipid metabolism in p53 wild-type liver cancers.

Ding Z, Pan Y, Shang T, Jiang T, Lin Y, Yang C, Pang S, Cui X, Wang Y, Feng XF, Xu M, Pei M, Chen Y, Li X, Ding J, Tan Y, Wang H, Dong L, Wang L
Nature communications 2023 Oct 7;14(1):6269

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PI3K/mTOR inhibitors promote G6PD autophagic degradation and exacerbate oxidative stress damage to radiosensitize small cell lung cancer.

Deng H, Chen Y, Wang L, Zhang Y, Hang Q, Li P, Zhang P, Ji J, Song H, Chen M, Jin Y
Cell death & disease 2023 Oct 6;14(10):652

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Prefrontal cortex-specific Dcc deletion induces schizophrenia-related behavioral phenotypes and fail to be rescued by olanzapine treatment.

Sun J, Cong Q, Sun T, Xi S, Liu Y, Zeng R, Wang J, Zhang W, Gao J, Qian J, Qin S
European journal of pharmacology 2023 Oct 5;956:175940

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C1632 inhibits ovarian cancer cell growth and migration by inhibiting LIN28 B/let-7/FAK signaling pathway and FAK phosphorylation.

Zhang Q, Shi M, Zheng R, Han H, Zhang X, Lin F
European journal of pharmacology 2023 Oct 5;956:175935

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VPS41-mediated incomplete autophagy aggravates cadmium-induced apoptosis in mouse hepatocytes.

Wang T, Yan L, Wang L, Sun J, Qu H, Ma Y, Song R, Tong X, Zhu J, Yuan Y, Gu J, Bian J, Liu Z, Zou H
Journal of hazardous materials 2023 Oct 5;459:132243

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Inhibition of adult hippocampal neurogenesis induced by postoperative CD8 + T-cell infiltration is associated with cognitive decline later following surgery in adult mice.

Li X, Wang H, Zhang Q, Sun X, Zhang M, Wang G
Journal of neuroinflammation 2023 Oct 5;20(1):227

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STING/ACSL4 axis-dependent ferroptosis and inflammation promote hypertension-associated chronic kidney disease.

Gao L, Zhang J, Yang T, Jiang L, Liu X, Wang S, Wang X, Huang Y, Wang H, Zhang M, Gong T, Ma L, Li C, He C, Meng XM, Wu Y
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Oct 4;31(10):3084-3103

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miR-124 and VAMP3 Act Antagonistically in Human Neuroblastoma.

Zhang X, Yang C, Meng Z, Zhong H, Hou X, Wang F, Lu Y, Guo J, Zeng Y
International journal of molecular sciences 2023 Oct 4;24(19)

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Heme oxygenase-1 increases intracellular iron storage and suppresses inflammatory response of macrophages by inhibiting M1 polarization.

Tang X, Li Y, Zhao J, Liang L, Zhang K, Zhang X, Yu H, Du H
Metallomics : integrated biometal science 2023 Oct 4;15(10)

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Transcriptome screening identifies TIPARP as an antiviral host factor against the Getah virus.

Jiao H, Yan Z, Zhai X, Yang Y, Wang N, Li X, Jiang Z, Su S
Journal of virology 2023 Oct 31;97(10):e0059123

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Aspartyl-tRNA synthetase 2 orchestrates iron-sulfur metabolism in hematopoietic stem cells via fine-tuning alternative RNA splicing.

Gu X, Li K, Zhang M, Chen Y, Zhou J, Yao C, Zang Y, He J, Wan J, Guo B
Cell reports 2023 Oct 31;42(10):113264

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Mechanotransduction in response to ECM stiffening impairs cGAS immune signaling in tumor cells.

Liu Y, Yao X, Zhao Y, Fang D, Shi L, Yang L, Song G, Cai K, Li L, Deng Q, Li M, Luo Z
Cell reports 2023 Oct 31;42(10):113213

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Intraperitoneal Injection of MCC950 Inhibits the Progression of Myopia in Form-Deprivation Myopic Mice.

Chen Z, Xiao K, Long Q
International journal of molecular sciences 2023 Oct 31;24(21)

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Caveolin-1 scaffolding domain peptide prevents corpus cavernosum fibrosis and erectile dysfunction in bilateral cavernous nerve injury-induced rats.

Xi Y, Ge Y, Hu D, Xia T, Chen J, Zhang C, Cui Y, Xiao H
The journal of sexual medicine 2023 Oct 31;20(11):1274-1284

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Lactobacillus casei combined with Lactobacillus reuteri alleviate pancreatic cancer by inhibiting TLR4 to promote macrophage M1 polarization and regulate gut microbial homeostasis.

Zhu Z, Yi B, Tang Z, Chen X, Li M, Xu T, Zhao Z, Tang C
BMC cancer 2023 Oct 30;23(1):1044

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Comparison of Multiple Strategies for Precision Transgene Knock-In in Gallus gallus Genome via Microhomology-Mediated End Joining.

Wang L, Sun J, Liu Z, Zheng Q, Wang G
International journal of molecular sciences 2023 Oct 29;24(21)

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RNF149 Promotes HCC Progression through Its E3 Ubiquitin Ligase Activity.

Guo Z, Jiang P, Dong Q, Zhang Y, Xu K, Zhai Y, He F, Tian C, Sun A
Cancers 2023 Oct 29;15(21)

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Sirtuin1 Mediates the Protective Effects of Echinacoside against Sepsis-Induced Acute Lung Injury via Regulating the NOX4-Nrf2 Axis.

Xie W, Deng L, Lin M, Huang X, Qian R, Xiong D, Liu W, Tang S
Antioxidants (Basel, Switzerland) 2023 Oct 29;12(11)

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Trim9 regulates the directional differentiation of retinal Müller cells to retinal ganglion cells.

Li J, Zeng Q
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 2023 Oct 28;48(10):1561-1571

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Poria cocos Lanostane Triterpenoids Extract Promotes Collagen and Hyaluronic Acid Production in D-Galactose-Induced Aging Rats.

Chao CL, Kuo HP, Huang HW, Cheng MY, Chao HF, Lu SM, Lin HC, Wang CJ, Chang TC, Wu CR
Life (Basel, Switzerland) 2023 Oct 28;13(11)

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Liensinine and neferine exert neuroprotective effects via the autophagy pathway in transgenic Caenorhabditis elegans.

Wu MC, Gao YH, Zhang C, Ma BT, Lin HR, Jiang JY, Xue MF, Li S, Wang HB
BMC complementary medicine and therapies 2023 Oct 27;23(1):386

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METTL3-regulated m6A modification impairs the decidualization of endometrial stromal cells by regulating YTHDF2-mediated degradation of FOXO1 mRNA in endometriosis-related infertility.

Li X, Jin J, Long X, Weng R, Xiong W, Liang J, Liu J, Sun J, Cai X, Zhang L, Liu Y
Reproductive biology and endocrinology : RB&E 2023 Oct 27;21(1):99

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Leveraging a disulfidptosis-related signature to predict the prognosis and immunotherapy effectiveness of cutaneous melanoma based on machine learning.

Zhao Y, Wei Y, Fan L, Nie Y, Li J, Zeng R, Li J, Zhan X, Lei L, Kang Z, Li J, Zhang W, Yang Z
Molecular medicine (Cambridge, Mass.) 2023 Oct 26;29(1):145

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Cordyceps militaris Solid Medium Extract Alleviates Lipoteichoic Acid-Induced MH-S Inflammation by Inhibiting TLR2/NF-κB/NLRP3 Pathways.

Wang X, Peng Z, Wang L, Zhang J, Zhang K, Guo Z, Xu G, Li J
International journal of molecular sciences 2023 Oct 24;24(21)

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Nuclear respiratory factor 1 drives hepatocellular carcinoma progression by activating LPCAT1-ERK1/2-CREB axis.

Liu R, Yin C, Zhao P, Guo B, Ke W, Zheng X, Xie D, Wang Y, Wang G, Jia Y, Gao Y, Hu W, Liu GL, Song Z
Biology direct 2023 Oct 24;18(1):67

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Metformin inhibits inflammatory response and endoplasmic reticulum stress to improve hypothalamic aging in obese mice.

Yang L, Lu P, Qi X, Yang Q, Liu L, Dou T, Guan Q, Yu C
iScience 2023 Oct 20;26(10):108082

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Dominant-negative HNF1α mutant promotes liver steatosis and inflammation by regulating hepatic complement factor D.

Liu M, Liu L, Guo H, Fan X, Liu T, Xu C, He Z, Song Y, Gao L, Shao S, Zhao J, Lu P
iScience 2023 Oct 20;26(10):108018

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Focused low-intensity pulsed ultrasound alleviates osteoarthritis via restoring impaired FUNDC1-mediated mitophagy.

Ye H, Li D, Wei X, Yu L, Jia L
iScience 2023 Oct 20;26(10):107772

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CHIP protects against septic acute kidney injury by inhibiting NLRP3-mediated pyroptosis.

Zhang H, Deng Z, Wang Y, Zheng X, Zhou L, Yan S, Wang Y, Dai Y, Kanwar YS, Deng F
iScience 2023 Oct 20;26(10):107762

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African Swine Fever Virus pF778R Attenuates Type I Interferon Response by Impeding STAT1 Nuclear Translocation.

Chen Q, Li L, Liu L, Liu Z, Guo S, Tan C, Chen H, Wang X
Virus research 2023 Oct 2;335:199190

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Identification of KLHDC2 as an efficient proximity-induced degrader of K-RAS, STK33, β-catenin, and FoxP3.

Röth S, Kocaturk NM, Sathyamurthi PS, Carton B, Watt M, Macartney TJ, Chan KH, Isidro-Llobet A, Konopacka A, Queisser MA, Sapkota GP
Cell chemical biology 2023 Oct 19;30(10):1261-1276.e7

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Insulin-induced gene 2 protects against hepatic ischemia-reperfusion injury via metabolic remodeling.

Wu Y, Li C, Khan AA, Chen K, Su R, Xu S, Sun Y, Gao F, Wang K, Wang X, Lian Z, Wang S, Yu M, Hu X, Yang F, Zheng S, Qiu N, Liu Z, Xu X
Journal of translational medicine 2023 Oct 19;21(1):739

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Targeting neoadjuvant chemotherapy-induced metabolic reprogramming in pancreatic cancer promotes anti-tumor immunity and chemo-response.

Tang R, Xu J, Wang W, Meng Q, Shao C, Zhang Y, Lei Y, Zhang Z, Liu Y, Du Q, Sun X, Wu D, Liang C, Hua J, Zhang B, Yu X, Shi S, Chinese Study Group for Pancreatic Cancer
Cell reports. Medicine 2023 Oct 17;4(10):101234

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Posttranslational ISGylation of NLRP3 by HERC enzymes facilitates inflammasome activation in models of inflammation.

Qin Y, Meng X, Wang M, Liang W, Xu R, Chen J, Song H, Fu Y, Li J, Gao C, Jia M, Zhao C, Zhao W
The Journal of clinical investigation 2023 Oct 16;133(20)

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PI3K/mTOR inhibitor VS-5584 combined with PLK1 inhibitor exhibits synergistic anti-cancer effects on non-small cell lung cancer.

Zhao S, Li Y, Li G, Ye J, Wang R, Zhang X, Li F, Gao C, Li J, Jiang J, Mi Y
European journal of pharmacology 2023 Oct 15;957:176004

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Silencing of ATP1A1 attenuates cell membrane disruption by nanosecond electric pulses.

Silkuniene G, Mangalanathan UM, Pakhomov AG, Pakhomova ON
Biochemical and biophysical research communications 2023 Oct 15;677:93-97

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Autophagy modulates the stability of Wee1 and cell cycle G2/M transition.

Han B, Chen Y, Song C, Chen Y, Chen Y, Ferguson D, Yang Y, He A
Biochemical and biophysical research communications 2023 Oct 15;677:63-69

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A unique inflammation-related mechanism by which high-fat diets induce depression-like behaviors in mice.

Yu H, Yu B, Qin X, Shan W
Journal of affective disorders 2023 Oct 15;339:180-193

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African swine fever virus MGF360-9L promotes viral replication by degrading the host protein HAX1.

Yang J, Yang B, Hao Y, Shi X, Yang X, Zhang D, Zhao D, Yan W, Chen L, Bie X, Chen G, Zhu Z, Li D, Shen C, Li G, Liu X, Zheng H, Zhang K
Virus research 2023 Oct 15;336:199198

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Downregulation of XBP1s aggravates lipopolysaccharide-induced inflammation by promoting NF-κB and NLRP3 pathways' activation in goat endometrial epithelial cells.

Gao K, Yi Y, Xue Z, Wang Z, Huang S, Zhang B, Lin P, Wang A, Chen H, Jin Y
Theriogenology 2023 Oct 15;210:119-132

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Leptin Promotes the Proliferation and Neuronal Differentiation of Neural Stem Cells through the Cooperative Action of MAPK/ERK1/2, JAK2/STAT3 and PI3K/AKT Signaling Pathways.

Tan R, Hu X, Wang X, Sun M, Cai Z, Zhang Z, Fu Y, Chen X, An J, Lu H
International journal of molecular sciences 2023 Oct 13;24(20)

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Flubendazole Enhances the Inhibitory Effect of Paclitaxel via HIF1α/PI3K/AKT Signaling Pathways in Breast Cancer.

Zhou Y, Liao M, Li Z, Ye J, Wu L, Mou Y, Fu L, Zhen Y
International journal of molecular sciences 2023 Oct 12;24(20)

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METTL3/IGF2BP2 axis affects the progression of colorectal cancer by regulating m6A modification of STAG3.

Yi J, Peng F, Zhao J, Gong X
Scientific reports 2023 Oct 12;13(1):17292

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Peptide Characterization of Bovine Myocardium Hydrolysates and Its Ameliorative Effects on Doxorubicin-Induced Myocardial Injury in H9c2 Cells and in Mice.

Li W, Lv M, Zhang T, Zhou M, Zheng L, Song T, Zhao M
Journal of agricultural and food chemistry 2023 Oct 11;71(40):14562-14574

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AP4M1 as a prognostic biomarker associated with cell proliferation, migration and immune regulation in hepatocellular carcinoma.

Peng Y, Li X, Kang K, Zhou Y
Cancer cell international 2023 Oct 11;23(1):235

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Comparing the value of mono- vs coculture for high-throughput compound screening in hematological malignancies.

Herbst SA, Kim V, Roider T, Schitter EC, Bruch PM, Liebers N, Kolb C, Knoll M, Lu J, Dreger P, Müller-Tidow C, Zenz T, Huber W, Dietrich S
Blood advances 2023 Oct 10;7(19):5925-5936

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Cryo-EM structure of severe fever with thrombocytopenia syndrome virus.

Du S, Peng R, Xu W, Qu X, Wang Y, Wang J, Li L, Tian M, Guan Y, Wang J, Wang G, Li H, Deng L, Shi X, Ma Y, Liu F, Sun M, Wei Z, Jin N, Liu W, Qi J, Liu Q, Liao M, Li C
Nature communications 2023 Oct 10;14(1):6333

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Novel c-Myc G4 stabilizer EP12 promotes myeloma cytotoxicity by disturbing NF-κB signaling.

Yao R, Zhang Y, Zeng Y, Zhang Y, Liu L, Gao J
Experimental cell research 2023 Oct 1;431(1):113759

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Erythrocyte ENT1-AMPD3 Axis is an Essential Purinergic Hypoxia Sensor and Energy Regulator Combating CKD in a Mouse Model.

Chen C, Xie T, Zhang Y, Wang Y, Yu F, Lin L, Zhang W, Brown BC, Zhang X, Kellems RE, D'Alessandro A, Xia Y
Journal of the American Society of Nephrology : JASN 2023 Oct 1;34(10):1647-1671

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Inulin alleviates neuroinflammation and oxidative stress induced by perinatal 2-ethylhexyl diphenyl phosphate (EHDPHP) exposure in female mice and offspring.

Li XW, Qiu F, Liu Y, Chen LJ, Li JH, Liu JL, Yang JZ, Hsu C, Chen L, Zeng JH, Xie XL, Wang Q
Ecotoxicology and environmental safety 2023 Oct 1;264:115396

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Complement C1q drives microglia-dependent synaptic loss and cognitive impairments in a mouse model of lipopolysaccharide-induced neuroinflammation.

Wu X, Gao Y, Shi C, Tong J, Ma D, Shen J, Yang J, Ji M
Neuropharmacology 2023 Oct 1;237:109646

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Umbilical cord mesenchymal stem cell-conditioned medium inhibits microglial activation to ameliorate neuroinflammation in amyotrophic lateral sclerosis mice and cell models.

Tang J, Kang Y, Zhou Y, Chen Q, Lan J, Liu X, Peng Y
Brain research bulletin 2023 Oct 1;202:110760

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Dendrobium mixture ameliorates hepatic injury induced by insulin resistance in vitro and in vivo through the downregulation of AGE/RAGE/Akt signaling pathway.

Zhuang S, Zhou X, Yang X, Chang D, Chen T, Sun Y, Wang C, Zhang C, Jiang J, Chen Y, Lin X, Wang X, Yu W, Lin X, He C, Zheng Y, Zhang J, Shi H
Heliyon 2023 Nov;9(11):e22007

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Arginase2 mediates contrast-induced acute kidney injury via facilitating nitrosative stress in tubular cells.

Zhou LY, Liu K, Yin WJ, Xie YL, Wang JL, Zuo SR, Tang ZY, Wu YF, Zuo XC
Redox biology 2023 Nov;67:102929

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Tobacco toxins induce osteoporosis through ferroptosis.

Jing Z, Li Y, Zhang H, Chen T, Yu J, Xu X, Zou Y, Wang X, Xiang K, Gong X, He P, Fu Y, Ren M, Ji P, Yang S
Redox biology 2023 Nov;67:102922

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The novel β-TrCP protein isoform hidden in circular RNA confers trastuzumab resistance in HER2-positive breast cancer.

Wang S, Wang Y, Li Q, Li X, Feng X, Zeng K
Redox biology 2023 Nov;67:102896

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TRIM16 E121D variant affects the risk and prognosis of hepatocellular carcinoma by modulating the Wnt/β-catenin pathway.

Li S, Wang J, Chen H, Hou J, Shen T, Li J, Zhou B, Zhang B, Liu H, Jiang DK
Molecular carcinogenesis 2023 Nov;62(11):1686-1699

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LKB1 loss promotes colorectal cancer cell metastasis through regulating TNIK expression and actin cytoskeleton remodeling.

Hu G, Huang N, Zhang J, Zhang D, Wang S, Zhang Y, Wang L, Du Y, Kuang S, Ma K, Zhu H, Xu N, Liu M
Molecular carcinogenesis 2023 Nov;62(11):1659-1672

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Rutaecarpine Mitigates Cognitive Impairment by Balancing Mitochondrial Function Through Activation of the AMPK/PGC1α Pathway.

Gong M, Jia J
Molecular neurobiology 2023 Nov;60(11):6598-6612

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A new ferrocene derivative blocks K-Ras localization and function by oxidative modification at His95.

Rehl KM, Selvakumar J, Pitsch RL, Hoang D, Arumugam K, Harshman SW, Gorfe AA, Cho KJ
Life science alliance 2023 Nov;6(11)

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RNA‑binding protein quaking 5 inhibits the progression of non‑small cell lung cancer by upregulating netrin‑4 expression.

Wu Z, Liu S, Pang G, Jiang H
Oncology reports 2023 Nov;50(5)

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LncRNA MALAT1 Promoted Neuronal Necroptosis in Cerebral Ischemia-reperfusion Mice by Stabilizing HSP90.

Huang S, Hou D, Zhang L, Pei C, Liang J, Li J, Yang G, Yu D
Neurochemical research 2023 Nov;48(11):3457-3471

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Ginsenoside Rg5 promotes wound healing in diabetes by reducing the negative regulation of SLC7A11 on the efferocytosis of dendritic cells.

Xia W, Zhu Z, Xiang S, Yang Y
Journal of ginseng research 2023 Nov;47(6):784-794

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The cysteine-rich receptor-like kinase CRK4 contributes to the different drought stress response between Columbia and Landsberg erecta.

Zhao M, Li M, Huang M, Liang C, Chen D, Hwang I, Zhang W, Wang M
Plant, cell & environment 2023 Nov;46(11):3258-3272

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Inhibition of TMEM16A improves cisplatin-induced acute kidney injury via preventing DRP1-mediated mitochondrial fission.

Li XL, Liu XW, Liu WL, Lin YQ, Liu J, Peng YS, Cheng LM, Du YH
Acta pharmacologica Sinica 2023 Nov;44(11):2230-2242

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Cardiomyocyte peroxisome proliferator-activated receptor α prevents septic cardiomyopathy via improving mitochondrial function.

Zhu XX, Wang X, Jiao SY, Liu Y, Shi L, Xu Q, Wang JJ, Chen YE, Zhang Q, Song YT, Wei M, Yu BQ, Fielitz J, Gonzalez FJ, Du J, Qu AJ
Acta pharmacologica Sinica 2023 Nov;44(11):2184-2200

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Neuroprotective Effect of Hydrogen Sulfide Subchronic Treatment Against TBI-Induced Ferroptosis and Cognitive Deficits Mediated Through Wnt Signaling Pathway.

Chen J, Chen Z, Yu D, Yan Y, Hao X, Zhang M, Zhu T
Cellular and molecular neurobiology 2023 Nov;43(8):4117-4140

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Inflammatory Cell-Derived MYDGF Attenuates Endothelial LDL Transcytosis to Protect Against Atherogenesis.

Xu J, Ma H, Shi L, Zhou H, Cheng Y, Tong J, Meng B, Xu X, He K, Ding S, Zhang J, Yue L, Xiang G
Arteriosclerosis, thrombosis, and vascular biology 2023 Nov;43(11):e443-e467

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Polydatin inhibited TNF-α-induced apoptosis of skeletal muscle cells through AKT-mediated p38 MAPK and NF-κB pathways.

Liu Y, Xie F, Lu C, Zhou Z, Li S, Zhong J, Li Q, Shao X
General physiology and biophysics 2023 Nov;42(6):521-529

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UBE3B promotes breast cancer progression by antagonizing HIF-2α degradation.

Wang Y, Liu X, Wang M, Wang Y, Wang S, Jin L, Liu M, Zhou J, Chen Y
Oncogene 2023 Nov;42(46):3394-3406

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Fusaric acid inhibits proliferation and induces apoptosis through triggering endoplasmic reticulum stress in MCF-7 human breast cancer cells.

Zhang J, Yuan H, Li W, Chen S, Liu S, Li C, Yao X
Mycotoxin research 2023 Nov;39(4):347-364

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Genetic Architecture and Functional Implications of the CSF-Contacting Nucleus.

Song S, Yuan Y, Xu L, Jiang J, Li Y, Yan Y, Li Q, Zhou F, Cao J, Zhang L
Neuroscience bulletin 2023 Nov;39(11):1638-1654

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UFMylation of HRD1 regulates endoplasmic reticulum homeostasis.

Luo H, Jiao QB, Shen CB, Gong WY, Yuan JH, Liu YY, Chen Z, Liu J, Xu XL, Cong YS, Zhang XW
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23221

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RUNX1 promotes proliferation and migration in non-small cell lung cancer cell lines via the mTOR pathway.

Ma H, Jiang S, Yuan Y, Li J, Li Y, Lv Y, Du T, Guan J, Jiang X, Tian L, Zheng Q, Yang L, Li Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23195

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Potent gene delivery from fluorinated poly(β-amino ester) in adhesive and suspension difficult-to-transfect cells for apoptosis and ferroptosis.

Deng Y, Zhang J, Sun X, Li L, Zhou M, Liu S, Chen F, Pan C, Yu Z, Li M, Zhong W, Zeng M
Journal of controlled release : official journal of the Controlled Release Society 2023 Nov;363:597-605

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Neuropathological hallmarks in autopsied cases with mitochondrial diseases caused by the mitochondrial 3243A>G mutation.

Miyahara H, Tamai C, Inoue M, Sekiguchi K, Tahara D, Tahara N, Takeda K, Arafuka S, Moriyoshi H, Koizumi R, Akagi A, Riku Y, Sone J, Yoshida M, Ihara K, Iwasaki Y
Brain pathology (Zurich, Switzerland) 2023 Nov;33(6):e13199

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M2 macrophage exosomal LINC01001 promotes non-small cell lung cancer development by affecting METTL3 and glycolysis pathway.

Xu L, Li K, Li J, Xu F, Liang S, Kong Y, Chen B
Cancer gene therapy 2023 Nov;30(11):1569-1580

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Targeting SOD1 via RNAi with PEGylated graphene oxide nanoparticles in platinum-resistant ovarian cancer.

Szénási A, Sivasudhan E, Du H, Zhang P, Huang J, Zhang Z, Rocha S, Wang M
Cancer gene therapy 2023 Nov;30(11):1554-1568

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Combination of hyperlipidemia and 17β-Estradiol induces TMJOA-like pathological changes in rats.

Zhao Y, Gan YH
Oral diseases 2023 Nov;29(8):3640-3653

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Involvement of ferroptosis in Porphyromonas gingivalis lipopolysaccharide-stimulated periodontitis in vitro and in vivo.

Qiao S, Li B, Cai Q, Li Z, Yin Z, He J, Li Y, Meng W
Oral diseases 2023 Nov;29(8):3571-3582

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Acetyl zingerone ameliorates osteoarthritis by inhibiting chondrocyte programmed cell death.

Chen X, Chen J, Miao C, Yin G, Zhang Z, Sun R, Ni S
Molecular medicine reports 2023 Nov;28(5)

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Knockdown of Bach1 protects periodontal bone regeneration from inflammatory damage.

Yuan Z, Li J, Zou X, Liu C, Lu J, Ni C, Tang L, Wu X, Yan F
Journal of cellular and molecular medicine 2023 Nov;27(22):3465-3477

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Transcriptomics and metabolomics study in mouse kidney of the molecular mechanism underlying energy metabolism response to hypoxic stress in highland areas.

Gao Y, Long Q, Yang H, Hu Y, Xu Y, Tang C, Gu C, Yong S
Experimental and therapeutic medicine 2023 Nov;26(5):533

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An HPK1 inhibitor enhanced the tumour response to anti-PD-1 immunotherapy in non-Hodgkin's lymphoma.

Yang L, Zhao Q, Chen T, Liu W, Qiu X, Chen J, Huang S, Huang R, Dong L
Clinical and experimental medicine 2023 Nov;23(7):3767-3780

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Mulberry leaf flavonoids activate BAT and induce browning of WAT to improve type 2 diabetes via regulating the AMPK/SIRT1/PGC-1α signaling pathway.

Cheng L, Shi L, He C, Wang C, Lv Y, Li H, An Y, Duan Y, Dai H, Zhang H, Huang Y, Fu W, Sun W, Zhao B
Chinese journal of natural medicines 2023 Nov;21(11):812-829

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Sphingosine kinase 1/S1P receptor signaling axis is essential for cellular uptake of Neisseria meningitidis in brain endothelial cells.

Fohmann I, Weinmann A, Schumacher F, Peters S, Prell A, Weigel C, Spiegel S, Kleuser B, Schubert-Unkmeir A
PLoS pathogens 2023 Nov;19(11):e1011842

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Autophagy regulation and protein kinase activity of PIK3C3 controls sertoli cell polarity through its negative regulation on SCIN (scinderin).

Wang K, Kong F, Qiu Y, Chen T, Fu J, Jin X, Su Y, Gu Y, Hu Z, Li J
Autophagy 2023 Nov;19(11):2934-2957

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Ferroptosis inhibition protects vascular endothelial cells and maintains integrity of the blood-spinal cord barrier after spinal cord injury.

Li W, Zhao X, Zhang R, Liu X, Qi Z, Zhang Y, Yang W, Pang Y, Zhao C, Fan B, Ran N, Zhang J, Kong X, Feng S, Yao X
Neural regeneration research 2023 Nov;18(11):2474-2481

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Angelica sinensis polysaccharides ameliorated 5-Fluorouracil-induced damage of early B cell progenitors by alleviating oxidative stress of IL-7 producing mesenchymal stem and progenitor cells.

Xiao H, Wang Y, Wang Z, Wang B, Hu L, Hou J, Du K, Sun N, Wang L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115599

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Fructus Lycii and Salvia miltiorrhiza Bunge extract attenuate oxidative stress-induced photoreceptor ferroptosis in retinitis pigmentosa.

Yang Y, Wang Y, Deng Y, Lu J, Xiao L, Li J, Zhou Y, Nie F, Chen X, Peng J, Tan H, Qin Y, Peng Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115547

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Design and synthesis of 3,4-seco-lupane triterpene derivatives to resist myocardial ischemia-reperfusion injury by inhibiting oxidative stress-mediated mitochondrial dysfunction via the PI3K/AKT/HIF-1α axis.

Teng H, Wu D, Lu L, Gao C, Wang H, Zhao Y, Wang L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115452

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L-arabinose Attenuates LPS-Induced Intestinal Inflammation and Injury through Reduced M1 Macrophage Polarization.

Kang L, Pang J, Zhang X, Liu Y, Wu Y, Wang J, Han D
The Journal of nutrition 2023 Nov;153(11):3327-3340

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Meroterpenoids from Daphne genkwa shows promising in vitro antitumor activity via inhibiting PI3K/Akt/mTOR signaling pathway in A549 cells.

Ma RF, Liu H, Zhao XC, Shan P, Sun P, Xue JJ, Wei G, Zhang H
Bioorganic chemistry 2023 Nov;140:106803

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Effects of the PI3K/Akt/HO-1 pathway on autophagy in a sepsis-induced acute lung injury mouse model.

Tian J, Li Y, Mao X, Xie K, Zheng Y, Yu Y, Yu Y
International immunopharmacology 2023 Nov;124(Pt B):111063

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E3 ubiquitin ligase Siah1 aggravates NAFLD through Scp2 ubiquitination.

Zhu Z, Hu X, Liu K, Li J, Fan K, Wang H, Wang L, He L, Ma Y, Guan R, Wang Z
International immunopharmacology 2023 Nov;124(Pt A):110897

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Pachymic acid suppresses the inflammatory response of chondrocytes and alleviates the progression of osteoarthritis via regulating the Sirtuin 6/NF-κB signal axis.

Wu Y, Ying J, Zhu X, Xu C, Wu L
International immunopharmacology 2023 Nov;124(Pt A):110854

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The STING inhibitor C-176 attenuates MPTP-induced neuroinflammation and neurodegeneration in mouse parkinsonian models.

Wang B, Wang Y, Qiu J, Gao S, Yu S, Sun D, Lou H
International immunopharmacology 2023 Nov;124(Pt A):110827

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Human placental mesenchymal stromal cells modulate IFN-γ and IL-10 secretion by CD4(+)T cells via CD73, and alleviate intestinal damage in mice with graft-versus-host disease.

Zhang J, Zhao Y, Zhang H, Han K, Ma J, Xiong Y, Wang G, Luan X
International immunopharmacology 2023 Nov;124(Pt A):110767

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Glycosides of Buyang Huanwu decoction inhibits pyroptosis associated with cerebral ischemia-reperfusion through Nrf2-mediated antioxidant signaling pathway both in vivo and in vitro.

She Y, Shao L, Jiao K, Sun R, Lang T, Long H, Tang Y, Zhang W, Ding C, Deng C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155001

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Mesenchymal stem cell-derived exosomal miR-548x-3p inhibits pyroptosis of vascular endothelial cells through HMGB1 in heat stroke.

Pei Y, Ma W, Wang H, Chen F, Xiao W, Fan M, Han X, Cao Y
Genomics 2023 Nov;115(6):110719

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Inhibition of STAT-mediated cytokine responses to chemically-induced colitis prevents inflammation-associated neurobehavioral impairments.

Sin R, Sotogaku N, Ohnishi YN, Shuto T, Kuroiwa M, Kawahara Y, Sugiyama K, Murakami Y, Kanai M, Funakoshi H, Chakraborti A, Bibb JA, Nishi A
Brain, behavior, and immunity 2023 Nov;114:173-186

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KLF5/MDM2 Axis Modulates Oxidative Stress and Epithelial-Mesenchymal Transition in Human Lens Epithelial Cells: The Role in Diabetic Cataract.

Li X, Chen D, Ouyang B, Wang S, Li Y, Li L, Zhu S, Zheng G
Laboratory investigation; a journal of technical methods and pathology 2023 Nov;103(11):100226

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Guanxin V alleviates ventricular remodeling by promoting transforming growth factor-beta 1-mediated proteasomal degradation of Vimentin.

Gu N, Liang B
Poultry science 2023 Nov;102(11):103026

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The Peptide AWRK6 Alleviates Lipid Accumulation in Hepatocytes by Inhibiting miR-5100 Targeting G6PC.

Liu J, Liu Y, Wang Q, Jin L, Zhang D
International journal of molecular sciences 2023 Nov 9;24(22)

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Aqueous Extract of Brassica rapa L.'s Impact on Modulating Exercise-Induced Fatigue via Gut-Muscle Axis.

Wang C, Zhu H, Cheng Y, Guo Y, Zhao Y, Qian H
Nutrients 2023 Nov 9;15(22)

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Duck Tembusu virus induces incomplete autophagy via the ERK/mTOR and AMPK/mTOR signalling pathways to promote viral replication in neuronal cells.

Wang Q, Jiang Y, Bao G, Yao W, Yang Q, Chen S, Wang G
Veterinary research 2023 Nov 7;54(1):103

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Bone marrow immune cells respond to fluctuating nutritional stress to constrain weight regain.

Zhou HY, Feng X, Wang LW, Zhou R, Sun H, Chen X, Lu RB, Huang Y, Guo Q, Luo XH
Cell metabolism 2023 Nov 7;35(11):1915-1930.e8

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Cuproptosis-related gene DLAT serves as a prognostic biomarker for immunotherapy in clear cell renal cell carcinoma: multi-database and experimental verification.

Huang S, Cai C, Zhou K, Wang X, Wang X, Cen D, Weng G
Aging 2023 Nov 7;15(21):12314-12329

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An ULK1/2-PXN mechanotransduction pathway suppresses breast cancer cell migration.

Liang P, Zhang J, Wu Y, Zheng S, Xu Z, Yang S, Wang J, Ma S, Xiao L, Hu T, Jiang W, Huang C, Xing Q, Kundu M, Wang B
EMBO reports 2023 Nov 6;24(11):e56850

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Chromofungin, a chromogranin A-derived peptide, protects against sepsis-induced acute lung injury by inhibiting LBP/TLR4-dependent inflammatory signaling.

Zhou W, Kang S, Wang F, Qin Y, Liu J, Xiao X, Chen X, Zhang D
European journal of pharmacology 2023 Nov 5;958:176043

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Discovery of a novel dual-target inhibitor of CDK12 and PARP1 that induces synthetic lethality for treatment of triple-negative breast cancer.

Zhang L, Zhen Y, Feng L, Li Z, Lu Y, Wang G, Ouyang L
European journal of medicinal chemistry 2023 Nov 5;259:115648

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Cell volume controlled by LRRC8A-formed volume-regulated anion channels fine-tunes T cell activation and function.

Wang Y, Sun Z, Ping J, Tang J, He B, Chang T, Zhou Q, Yuan S, Tang Z, Li X, Lu Y, He R, He X, Liu Z, Yin L, Wu N
Nature communications 2023 Nov 4;14(1):7075

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PGAM5 degrades PDCoV N protein and activates type I interferon to antagonize viral replication.

Yang X, Kong N, Qin W, Zhai X, Song Y, Tong W, Li L, Liu C, Zheng H, Yu H, Zhang W, Tong G, Shan T
Journal of virology 2023 Nov 30;97(11):e0147023

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Alphavirus-based replicons demonstrate different interactions with host cells and can be optimized to increase protein expression.

Dominguez F, Palchevska O, Frolova EI, Frolov I
Journal of virology 2023 Nov 30;97(11):e0122523

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Alphavirus-induced transcriptional and translational shutoffs play major roles in blocking the formation of stress granules.

Frolova EI, Palchevska O, Dominguez F, Frolov I
Journal of virology 2023 Nov 30;97(11):e0097923

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Jun-APOE-LRP1 axis promotes tumor metastasis in colorectal cancer.

He L, Shi M, Ren S, Zhang J, Tian Y, Yang X, Liu H
Biomolecules & biomedicine 2023 Nov 3;23(6):1026-1037

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Selective activator of human ClpP triggers cell cycle arrest to inhibit lung squamous cell carcinoma.

Zhou LL, Zhang T, Xue Y, Yue C, Pan Y, Wang P, Yang T, Li M, Zhou H, Ding K, Gan J, Ji H, Yang CG
Nature communications 2023 Nov 3;14(1):7069

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Spliceosome component Usp39 contributes to hepatic lipid homeostasis through the regulation of autophagy.

Cui D, Wang Z, Dang Q, Wang J, Qin J, Song J, Zhai X, Zhou Y, Zhao L, Lu G, Liu H, Liu G, Liu R, Shao C, Zhang X, Liu Z
Nature communications 2023 Nov 3;14(1):7032

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A bacteria-derived tetramerized protein ameliorates nonalcoholic steatohepatitis in mice via binding and relocating acetyl-coA carboxylase.

Lin Y, Yang M, Huang L, Yang F, Fan J, Qiang Y, Chang Y, Zhou W, Yan L, Xiong J, Ping J, Chen S, Men D, Li F
Cell reports 2023 Nov 28;42(11):113453

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Targeting PRMT1-mediated SRSF1 methylation to suppress oncogenic exon inclusion events and breast tumorigenesis.

Li WJ, Huang Y, Lin YA, Zhang BD, Li MY, Zou YQ, Hu GS, He YH, Yang JJ, Xie BL, Huang HH, Deng X, Liu W
Cell reports 2023 Nov 28;42(11):113385

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Kaempferol Improves Breast Cancer-Related Depression through the COX-2/PGE2 Pathway.

Zhu Q, Han Y, He Y, Fu Y, Yang H, Chen Y, Shi Y
Frontiers in bioscience (Landmark edition) 2023 Nov 28;28(11):311

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A Mild Hyperthermia Hollow Carbon Nanozyme as Pyroptosis Inducer for Boosted Antitumor Immunity.

Tao N, Jiao L, Li H, Deng L, Wang W, Zhao S, Chen W, Chen L, Zhu C, Liu YN
ACS nano 2023 Nov 28;17(22):22844-22858

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LSM14B is essential for oocyte meiotic maturation by regulating maternal mRNA storage and clearance.

Wan Y, Yang S, Li T, Cai Y, Wu X, Zhang M, Muhammad T, Huang T, Lv Y, Chan WY, Lu G, Li J, Sha QQ, Chen ZJ, Liu H
Nucleic acids research 2023 Nov 27;51(21):11652-11667

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FUNDC2, a mitochondrial outer membrane protein, mediates triple-negative breast cancer progression via the AKT/GSK3β/GLI1 pathway.

Yin L, Cao R, Liu Z, Luo G, Li Y, Zhou X, Chen X, Wu Y, He J, Zu X, Shen Y
Acta biochimica et biophysica Sinica 2023 Nov 25;55(11):1770-1783

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The Protective Effects of Reineckia carnea Ether Fraction against Alzheimer's Disease Pathology: An Exploration in Caenorhabditis elegans Models.

Fu HJ, Zhou XY, Li YP, Chen X, He YN, Qin DL, Yu L, Yu CL, Wu JM, Wu AG, Zhou XG
International journal of molecular sciences 2023 Nov 20;24(22)

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RGS5 maintaining vascular homeostasis is altered by the tumor microenvironment.

Kong P, Wang X, Gao YK, Zhang DD, Huang XF, Song Y, Zhang WD, Guo RJ, Li H, Han M
Biology direct 2023 Nov 20;18(1):78

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Progesterone Activates the Histone Lactylation-Hif1α-glycolysis Feedback Loop to Promote Decidualization.

Zhao W, Wang Y, Liu J, Yang Q, Zhang S, Hu X, Shi Z, Zhang Z, Tian J, Chu D, An L
Endocrinology 2023 Nov 20;165(1)

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Attenuation of estrogen and its receptors in the post-menopausal stage exacerbates dyslipidemia and leads to cognitive impairment.

Meng Q, Chao Y, Zhang S, Ding X, Feng H, Zhang C, Liu B, Zhu W, Li Y, Zhang Q, Tong H, Wu L, Bian H
Molecular brain 2023 Nov 20;16(1):80

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Cinnamaldehyde Alleviates Bone Loss by Targeting Oxidative Stress and Mitochondrial Damage via the Nrf2/HO-1 Pathway in BMSCs and Ovariectomized Mice.

Lin BH, Ma RX, Wu JT, Du SQ, Lv YY, Yu HN, Zhang W, Mao SM, Liu GY, Bu YT, Chen ZH, Jin C, Wu ZY, Yang L
Journal of agricultural and food chemistry 2023 Nov 2;

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Iron derived from NCOA4-mediated ferritinophagy causes cellular senescence via the cGAS-STING pathway.

Li HY, Wei TT, Zhuang M, Tan CY, Xie TH, Cai J, Yao Y, Zhu L
Cell death discovery 2023 Nov 18;9(1):419

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Ferroptosis sensitization in glioma: exploring the regulatory mechanism of SOAT1 and its therapeutic implications.

Sun S, Qi G, Chen H, He D, Ma D, Bie Y, Xu L, Feng B, Pang Q, Guo H, Zhang R
Cell death & disease 2023 Nov 18;14(11):754

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ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury.

Zhang Y, Fan Y, Hu H, Zhang X, Wang Z, Wu Z, Wang L, Yu X, Song X, Xiang P, Zhang X, Wang T, Tan S, Li C, Gao L, Liang X, Li S, Li N, Yue X, Ma C
Nature communications 2023 Nov 18;14(1):7527

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DLX2 promotes osteosarcoma epithelial-mesenchymal transition and doxorubicin resistance by enhancing HOXC8-CDH2 axis.

Zhang B, Du X, Fan Y, Qu G, Pang LK, Zhao R, Yao W
iScience 2023 Nov 17;26(11):108272

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AKAP150 from nucleus accumbens dopamine D1 and D2 receptor-expressing medium spiny neurons regulates morphine withdrawal.

Bai X, Zhang K, Ou C, Mu Y, Chi D, Zhang J, Huang J, Li X, Zhang Y, Huang W, Ouyang H
iScience 2023 Nov 17;26(11):108227

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Cullin 5 aggravates hypoxic pulmonary hypertension by activating TRAF6/NF-κB/HIF-1α/VEGF.

Wang L, Huang J, Zhang R, Zhang M, Guo Y, Liu Y, Li C, Wang W, Ying S, Liu J, Wang C
iScience 2023 Nov 17;26(11):108199

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Oral pathogens exacerbate Parkinson's disease by promoting Th1 cell infiltration in mice.

Bai XB, Xu S, Zhou LJ, Meng XQ, Li YL, Chen YL, Jiang YH, Lin WZ, Chen BY, Du LJ, Tian GC, Liu Y, Duan SZ, Zhu YQ
Microbiome 2023 Nov 17;11(1):254

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Blockage of CacyBP inhibits macrophage recruitment and improves anti-PD-1 therapy in hepatocellular carcinoma.

Wang J, Zhang X, Ma X, Chen D, Cai M, Xiao L, Li J, Huang Z, Huang Y, Lian Y
Journal of experimental & clinical cancer research : CR 2023 Nov 16;42(1):303

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Simvastatin induces pyroptosis via ROS/caspase-1/GSDMD pathway in colon cancer.

Xie W, Peng M, Liu Y, Zhang B, Yi L, Long Y
Cell communication and signaling : CCS 2023 Nov 16;21(1):329

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Development of decoy oligonucleotide-warheaded chimeric molecules targeting STAT3.

Shih PC, Naganuma M, Tsuji G, Demizu Y, Naito M
Bioorganic & medicinal chemistry 2023 Nov 15;95:117507

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Structural determinants specific for retromer protein sorting nexin 5 in regulating subcellular retrograde membrane trafficking.

Chen Q, Sun M, Han X, Xu H, Liu Y
Journal of biomedical research 2023 Nov 15;37(6):492-506

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Inhibition of METTL3 alleviated LPS-induced alveolar epithelial cell apoptosis and acute lung injury via restoring neprilysin expression.

Jia J, Yuan Y, He Y, Wasti B, Duan W, Chen Z, Li D, Sun W, Zeng Q, Ma L, Zhang X, Liu S, Zhang D, Liu L, Liu Q, Liang H, Wang G, Xiang X, Xiao B
Life sciences 2023 Nov 15;333:122148

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Discovery of potent pyrrolo-pyrimidine and purine HDAC inhibitors for the treatment of advanced prostate cancer.

Moi D, Bonanni D, Belluti S, Linciano P, Citarella A, Franchini S, Sorbi C, Imbriano C, Pinzi L, Rastelli G
European journal of medicinal chemistry 2023 Nov 15;260:115730

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Sclerotome-derived PDGF signaling functions as a niche cue responsible for primitive erythropoiesis.

Mao A, Li Z, Ning G, Zhou Z, Wei C, Li J, He X, Wang Q
Development (Cambridge, England) 2023 Nov 15;150(22)

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Polyamine metabolism controls B-to-Z DNA transition to orchestrate DNA sensor cGAS activity.

Zhao C, Ma Y, Zhang M, Gao X, Liang W, Qin Y, Fu Y, Jia M, Song H, Gao C, Zhao W
Immunity 2023 Nov 14;56(11):2508-2522.e6

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Interactome profiling of Crimean-Congo hemorrhagic fever virus glycoproteins.

Dai S, Min YQ, Li Q, Feng K, Jiang Z, Wang Z, Zhang C, Ren F, Fang Y, Zhang J, Zhu Q, Wang M, Wang H, Deng F, Ning YJ
Nature communications 2023 Nov 14;14(1):7365

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The hippocampal FTO-BDNF-TrkB pathway is required for novel object recognition memory reconsolidation in mice.

Chang R, Zhu S, Peng J, Lang Z, Zhou X, Liao H, Zou J, Zeng P, Tan S
Translational psychiatry 2023 Nov 14;13(1):349

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Curcumin enhances elvitegravir concentration and alleviates oxidative stress and inflammatory response.

Godse S, Zhou L, Sinha N, Kodidela S, Kumar A, Singh UP, Kumar S
Scientific reports 2023 Nov 14;13(1):19864

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Ubc9 regulates the expression of MHC II in dendritic cells to enhance DSS-induced colitis by mediating RBPJ SUMOylation.

Zhang J, Chen L, Xu Q, Zou Y, Sun F, Zhou Q, Luo X, Li Y, Chen C, Zhang S, Xiong F, Yang P, Liu S, Wang CY
Cell death & disease 2023 Nov 13;14(11):737

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Identification of OLA1 as a Novel Protein Target of Vitexin to Ameliorate Dextran Sulfate Sodium-Induced Colitis with Tissue Thermal Proteome Profiling.

Li N, Wang R, Li W, Du Q, Deng Z, Fan Y, Zheng L
Journal of agricultural and food chemistry 2023 Nov 1;71(43):16057-16066

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Phlorizin Mitigates Dextran Sulfate Sodium-Induced Colitis in Mice by Modulating Gut Microbiota and Inhibiting Ferroptosis.

Cheng J, Liu D, Huang Y, Chen L, Li Y, Yang Z, Fu S, Hu G
Journal of agricultural and food chemistry 2023 Nov 1;71(43):16043-16056

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Col3a1 delivered via extracellular vesicles of Sertoli cells is essential for mice Sertoli cell proliferation.

Zhu Y, Lin Y, Zheng X, Wang H, Li Z, Sun F
Molecular and cellular endocrinology 2023 Nov 1;577:112036

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Oncogene SCARNA12 as a potential diagnostic biomarker for colorectal cancer.

Zhang H, Liu X, Zhang W, Deng J, Lin C, Qi Z, Li Y, Gu Y, Wang Q, Shen L, Wang Z
Molecular biomedicine 2023 Nov 1;4(1):37

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Genome-Wide CRISPR/Cas9 Screening Identifies That Mitochondrial Solute Carrier SLC25A23 Attenuates Type I IFN Antiviral Immunity via Interfering with MAVS Aggregation.

Zhang H, Li X, Wang Y, Liu X, Guo J, Wang Z, Zhang L, Xiong S, Dong C
Journal of immunology (Baltimore, Md. : 1950) 2023 Nov 1;211(9):1406-1417

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Soluble epoxide hydrolase deficiency attenuates airway inflammation in COPD via IRE1α/JNK/AP-1 signaling pathway.

Yu Y, Yang A, He X, Wu B, Wu Y, Li Y, Nie S, Xu B, Wang H, Yu G
Journal of inflammation (London, England) 2023 Nov 1;20(1):36

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Follicle-stimulating hormone orchestrates glucose-stimulated insulin secretion of pancreatic islets.

Cheng Y, Zhu H, Ren J, Wu HY, Yu JE, Jin LY, Pang HY, Pan HT, Luo SS, Yan J, Dong KX, Ye LY, Zhou CL, Pan JX, Meng ZX, Yu T, Jin L, Lin XH, Wu YT, Yang HB, Liu XM, Sheng JZ, Ding GL, Huang HF
Nature communications 2023 Nov 1;14(1):6991

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A human mitofusin 2 mutation can cause mitophagic cardiomyopathy.

Franco A, Li J, Kelly DP, Hershberger RE, Marian AJ, Lewis RM, Song M, Dang X, Schmidt AD, Mathyer ME, Edwards JR, Strong CG, Dorn GW
eLife 2023 Nov 1;12

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Photobiomodulation augments the effects of mitochondrial transplantation in the treatment of spinal cord injury in rats by facilitating mitochondrial transfer to neurons via Connexin 36.

Zhu Z, Li X, Wang X, Zuo X, Ma Y, Gao X, Liang Z, Zhang Z, Song Z, Ding T, Ju C, Li P, Li K, Zhang J, Quan H, Wang Z, Hu X
Bioengineering & translational medicine 2023 May;8(3):e10473

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Triptolide injection reduces Alzheimer's disease-like pathology in mice.

Mao R, Xu S, Sun G, Yu Y, Zuo Z, Wang Y, Yang K, Zhang Z, Yang W
Synapse (New York, N.Y.) 2023 May;77(3):e22261

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GSTP1-mediated S-glutathionylation of Pik3r1 is a redox hub that inhibits osteoclastogenesis through regulating autophagic flux.

Ji X, Hong J, Yang W, Yao M, Wang J, Jiang G, Wang Y, Li C, Lin J, Mou H, Li C, Li S, Chen Y, Shi M, Wang W, Lu F, Wu H, Zhao X, Qi Y, Yan S
Redox biology 2023 May;61:102635

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Relationship between IL-22 and IL-22BP in diabetic cognitive dysfunction.

Wang X, Yu S, Liu W, Lv P, Zhao L, Wang Y, Fu C, Meng L, Yang Q, Wang X, Huang Y, Zuo Z, Liu X
Acta diabetologica 2023 May;60(5):631-644

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Segregation of pathways leading to pexophagy.

Barone FG, Urbé S, Clague MJ
Life science alliance 2023 May;6(5)

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MSC-EXO and tempol ameliorate bronchopulmonary dysplasia in newborn rats by activating HIF-1α.

Wang J, Zhang A, Huang F, Xu J, Zhao M
Pediatric pulmonology 2023 May;58(5):1367-1379

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Cannabinoid type 2 receptor activation inhibits MPP(+)-induced M1 differentiation of microglia through activating PI3K/Akt/Nrf2 signal pathway.

Wang M, Liu M, Ma Z
Molecular biology reports 2023 May;50(5):4423-4433

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Discovery of a natural small-molecule AMP-activated kinase activator that alleviates nonalcoholic steatohepatitis.

Chen J, Xu L, Zhang XQ, Liu X, Zhang ZX, Zhu QM, Liu JY, Iqbal MO, Ding N, Shao CL, Wei MY, Gu YC
Marine life science & technology 2023 May;5(2):196-210

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Apelin-13 Improves Cognitive Impairment and Repairs Hippocampal Neuronal Damage by Activating PGC-1α/PPARγ Signaling.

Chen B, Wu J, Hu S, Liu Q, Yang H, You Y
Neurochemical research 2023 May;48(5):1504-1515

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TRPM8 promotes hepatocellular carcinoma progression by inducing SNORA55 mediated nuclear-mitochondrial communication.

Fu J, Liu G, Zhang X, Lei X, Liu Q, Qian K, Tong Q, Qin W, Li Z, Cao Z, Zhang J, Liu C, Wang Z, Liu Z, Liang XM, Yamamoto H, Xu X
Cancer gene therapy 2023 May;30(5):738-751

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PKM2 allosteric converter: A self-assembly peptide for suppressing renal cell carcinoma and sensitizing chemotherapy.

Wang L, Fu B, Hou DY, Lv YL, Yang G, Li C, Shen JC, Kong B, Zheng LB, Qiu Y, Wang HL, Liu C, Zhang JJ, Bai SY, Li LL, Wang H, Xu WH
Biomaterials 2023 May;296:122060

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Staphylococcus aureus induces mitophagy to promote its survival within bovine mammary epithelial cells.

Xu D, Hu G, Luo J, Cheng J, Wu D, Cheng L, Huang X, Fu S, Liu J
Veterinary microbiology 2023 May;280:109697

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CD98 regulates the phosphorylation of HER2 and a bispecific anti-HER2/CD98 antibody inhibits the growth signal of human breast cancer cells.

Yamasaki A, Maruyama-Takahashi K, Nishida K, Okazaki S, Okita K, Akiyama Y, Suzuki H, Endo Y, Masuko K, Masuko T, Tomioka Y
Genes to cells : devoted to molecular & cellular mechanisms 2023 May;28(5):374-382

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Curcumin protects against doxorubicin induced oxidative stress by regulating the Keap1-Nrf2-ARE and autophagy signaling pathways.

Liao D, Shangguan D, Wu Y, Chen Y, Liu N, Tang J, Yao D, Shi Y
Psychopharmacology 2023 May;240(5):1179-1190

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Lipid phosphatase SAC1 suppresses hepatitis B virus replication through promoting autophagic degradation of virions.

Zheng J, Deng Y, Wei Z, Zou H, Wen X, Cai J, Zhang S, Jia B, Lu M, Lu K, Lin Y
Antiviral research 2023 May;213:105601

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HIF-1α Mediates Arsenic-Induced Metabolic Reprogramming in Lung Bronchial Epithelial Cells.

Wang W, Zhang A
Biological trace element research 2023 May;201(5):2284-2293

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Proline promotes proliferation and drug resistance of multiple myeloma by downregulation of proline dehydrogenase.

Zhang J, Shi F, Liu X, Wu X, Hu C, Guo J, Yang Q, Xia J, He Y, An G, Qiu L, Feng X, Zhou W
British journal of haematology 2023 May;201(4):704-717

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Themis suppresses the effector function of CD8(+) T cells in acute viral infection.

Tang J, Jia X, Li J, Dong J, Wang J, Li W, Zhu Y, Hu Y, Hou B, Lin C, Cong Y, Ren T, Yan C, Yang H, Lai Q, Zheng H, Bao Y, Gautam N, Wang HR, Xu B, Chen XL, Li Q, Gascoigne NRJ, Fu G
Cellular & molecular immunology 2023 May;20(5):512-524

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Novel secreted STPKLRR from Vibrio splendidus AJ01 promotes pathogen internalization via mediating tropomodulin phosphorylation dependent cytoskeleton rearrangement.

Dai F, Guo M, Shao Y, Li C
PLoS pathogens 2023 May;19(5):e1011419

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EphA2 is a functional entry receptor for HCMV infection of glioblastoma cells.

Dong XD, Li Y, Li Y, Sun C, Liu SX, Duan H, Cui R, Zhong Q, Mou YG, Wen L, Yang B, Zeng MS, Luo MH, Zhang H
PLoS pathogens 2023 May;19(5):e1011304

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Bisphenol P exposure in C57BL/6 mice caused gut microbiota dysbiosis and induced intestinal barrier disruption via LPS/TLR4/NF-κB signaling pathway.

Ma N, Ma D, Liu X, Zhao L, Ma L, Ma D, Dong S
Environment international 2023 May;175:107949

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CDGSH iron sulfur domain 2 over-expression alleviates neuronal ferroptosis and brain injury by inhibiting lipid peroxidation via AKT/mTOR pathway following intracerebral hemorrhage in mice.

Li R, Zhang X, Gu L, Yuan Y, Luo X, Shen W, Xie Z
Journal of neurochemistry 2023 May;165(3):426-444

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Targeting ZDHHC9 potentiates anti-programmed death-ligand 1 immunotherapy of pancreatic cancer by modifying the tumor microenvironment.

Lin Z, Huang K, Guo H, Jia M, Sun Q, Chen X, Wu J, Yao Q, Zhang P, Vakal S, Zou Z, Gao H, Ci L, Chen J, Guo W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114567

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CBL0137 activates ROS/BAX signaling to promote caspase-3/GSDME-dependent pyroptosis in ovarian cancer cells.

Yang C, Wang ZQ, Zhang ZC, Lou G, Jin WL
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114529

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The impact and mechanism of TET3 overexpression on the progression of hepatic fibrosis.

Liu R, Feng L, Tang S, Liu Y, Yang Q
Epigenomics 2023 May;15(10):577-591

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Characterization and mechanisms of radioresistant lung squamous cell carcinoma cell lines.

Pan L, Wu Q, Wang Y, Ma S, Zhang S
Thoracic cancer 2023 May;14(14):1239-1250

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High-frequency repetitive transcranial magnetic stimulation protects against cerebral ischemia/reperfusion injury in rats: Involving the mitigation of ferroptosis and inflammation.

Zhou GJ, Liu DN, Huang XR, Wu Q, Feng WB, Zeng YH, Liu HY, Yu J, Xiao ZJ, Zhou J
Brain and behavior 2023 May;13(5):e2988

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NSUN2-mediated m(5) C RNA methylation dictates retinoblastoma progression through promoting PFAS mRNA stability and expression.

Zuo S, Li L, Wen X, Gu X, Zhuang A, Li R, Ye F, Ge S, Fan X, Fan J, Chai P, Lu L
Clinical and translational medicine 2023 May;13(5):e1273

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Integrating HPLC-Q-TOF-MS/MS, network pharmacology and experimental validation to decipher the chemical substances and mechanism of modified Gui-shao-liu-jun-zi decoction against gastric cancer.

Huang W, Wen F, Ruan S, Gu P, Gu S, Song S, Zhou J, Li Y, Liu J, Shu P
Journal of traditional and complementary medicine 2023 May;13(3):245-262

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Extracellular vesicles derived from Akkermansia muciniphila promote placentation and mitigate preeclampsia in a mouse model.

Chen Y, Ou Z, Pang M, Tao Z, Zheng X, Huang Z, Wen D, Li Q, Zhou R, Chen P, Situ B, Sheng C, Huang Y, Yue X, Zheng L, Huang L
Journal of extracellular vesicles 2023 May;12(5):e12328

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d-mannose blocks the interaction between keratinocytes and Th17 cells to alleviate psoriasis by inhibiting HIF-1α/CCL20 in mice.

Jiang Q, Wei B, You M, Zhou X
International immunopharmacology 2023 May;118:110087

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Tanshinone IIA analogue 15a inhibits NLRP3-mediated inflammation by activating mitophagy in macrophages to alleviate acute tubular necrosis.

Chen J, Luo W, Hu C, Ren M, Xu H, Xu X, Li W, Chen Y, Shao J, Xiao Z, Lv X, Liang G
International immunopharmacology 2023 May;118:110065

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C1q/tumor necrosis factor-related protein-9 exerts antioxidant and anti-inflammatory effects on oxygen-glucose deprivation/reoxygenation-stimulated neurons by modulating the Akt-GSK-3β-Nrf2 cascade via AdipoR1.

Wang J, Ren B, Yang Y, Li Y
International immunopharmacology 2023 May;118:110045

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Highly pathogenic porcine reproductive and respiratory syndrome virus-induced inflammatory response in porcine pulmonary microvascular endothelial cells and effects of herbal ingredients on main inflammatory molecules.

Wu Y, Song X, Li P, Wang Z, Zhao Z, Zhang T
International immunopharmacology 2023 May;118:110012

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Prognosis-related VDAC1 regulates the proliferation and apoptosis of osteosarcoma cells via the MAPK signaling pathway.

Cai X, Zhu S
Genomics 2023 May;115(3):110595

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Loureirin C inhibits ferroptosis after cerebral ischemia reperfusion through regulation of the Nrf2 pathway in mice.

Liu Y, Mi Y, Wang Y, Meng Q, Xu L, Liu Y, Zhou D, Wang Y, Liang D, Li W, Li N, Hou Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 May;113:154729

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Rs15285, a functional polymorphism located in lipoprotein lipase, predicts the risk and prognosis of gastric cancer.

Shen K, Zhou X, Hu L, Xiao J, Cheng Q, Wang Y, Liu K, Fan H, Xu Z, Yang L
Applied microbiology and biotechnology 2023 May;107(10):3243-3256

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Orai1 is an Entotic Ca(2+) Channel for Non-Apoptotic Cell Death, Entosis in Cancer Development.

Lee AR, Park CY
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 May;10(14):e2205913

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Astaxanthin protects human ARPE-19 retinal pigment epithelium cells from blue light-induced phototoxicity by scavenging singlet oxygen.

Kitao M, Yamaguchi A, Tomioka T, Kai K, Kamei Y, Sugimoto K, Akagawa M
Free radical research 2023 May-Jun;57(6-12):430-443

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Resistance to anti-HER2 therapy associated with the TSC2 nonsynonymous variant c.4349 C > G (p.Pro1450Arg) is reversed by CDK4/6 inhibitor in HER2-positive breast cancer.

Yang Z, Feng J, Jing J, Huang Y, Ye WW, Lei L, Wang XJ, Cao WM
NPJ breast cancer 2023 May 9;9(1):36

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Network pharmacology to explore the mechanism of scutellarin in the treatment of brain ischaemia and experimental verification of JAK2/STAT3 signalling pathway.

Jia QY, Chen HL, Qi Z, Zhang XL, Zheng LY, Liu TT, Yuan Y, Yang L, Wu CY
Scientific reports 2023 May 9;13(1):7557

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ER-localized JmjC domain-containing protein JMJD8 targets STING to promote immune evasion and tumor growth in breast cancer.

Yi J, Wang L, Du J, Wang M, Shen H, Liu Z, Qin Y, Liu J, Hu G, Xiao R, Ding J, Chen X, Wang H, Huang H, Ouyang G, Liu W
Developmental cell 2023 May 8;58(9):760-778.e6

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The relationship between gut microbiota and susceptibility to type 2 diabetes mellitus in rats.

An Y, Dai H, Duan Y, Cheng L, Shi L, He C, Wang C, Lv Y, Li H, Zhang H, Huang Y, Fu W, Sun W, Zhao B
Chinese medicine 2023 May 5;18(1):49

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The Screening of Broadly Neutralizing Antibodies Targeting the SARS-CoV-2 Spike Protein by mRNA Immunization in Mice.

An Z, Zhang Y, Yu X, Xia J, Yin Y, Li G, Lu J, Fan X, Xu Y
Pharmaceutics 2023 May 5;15(5)

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Mitochondrial Glycerol-3-Phosphate Dehydrogenase Restricts HBV Replication via the TRIM28-Mediated Degradation of HBx.

Liu C, Zhao K, Chen Y, Yao Y, Tang J, Wang J, Xu C, Yang Q, Zheng Y, Yuan Y, Sun H, Zhang Y, Zhou Y, Chen J, Wang Y, Wu C, Pei R, Chen X
Journal of virology 2023 May 31;97(5):e0058023

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Pancreatic tumors exhibit myeloid-driven amino acid stress and upregulate arginine biosynthesis.

Apiz Saab JJ, Dzierozynski LN, Jonker PB, AminiTabrizi R, Shah H, Menjivar RE, Scott AJ, Nwosu ZC, Zhu Z, Chen RN, Oh M, Sheehan C, Wahl DR, Pasca di Magliano M, Lyssiotis CA, Macleod KF, Weber CR, Muir A
eLife 2023 May 31;12

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Epsin1-mediated exosomal sorting of Dll4 modulates the tubular-macrophage crosstalk in diabetic nephropathy.

Liu JL, Zhang L, Huang Y, Li XH, Liu YF, Zhang SM, Zhao YE, Chen XJ, Liu Y, He LY, Dong Z, Liu FY, Sun L, Xiao L
Molecular therapy : the journal of the American Society of Gene Therapy 2023 May 3;31(5):1451-1467

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Targeting copper death genotyping associated gene RARRES2 suppresses glioblastoma progression and macrophages infiltration.

Yan T, Yang H, Meng Y, Li H, Jiang Q, Liu J, Xu C, Xue Y, Xu J, Song Y, Chu X, Wang L, Chen X, Che F
Cancer cell international 2023 May 29;23(1):105

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Pulsatilla Decoction and its bioactive component β-peltatin induce G2/M cell cycle arrest and apoptosis in pancreatic cancer.

Wu R, Xi Z, Liu M, Ren H, Dai R, Jiang X, Nik Nabil WN, Wang Y, Feng J, Chai Q, Dong Q, Xu H
Chinese medicine 2023 May 28;18(1):61

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Anti-Neuroinflammatory Meroterpenoids from a Chinese Collection of the Brown Alga Sargassum siliquastrum.

Qi Y, Wang Z, Zhang J, Tang S, Zhu H, Jiang B, Li X, Wang J, Sun Z, Zhao M, Zhu H, Yan P
Journal of natural products 2023 May 26;86(5):1284-1293

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The Nrf2/HMGB1/NF-κB axis modulates chondrocyte apoptosis and extracellular matrix degradation in osteoarthritis.

Li W, Tao C, Mao M, Zhu K
Acta biochimica et biophysica Sinica 2023 May 26;55(5):818-830

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Apolipoprotein A4 Elevates Sympathetic Activity and Thermogenesis in Male Mice.

Kuo HN, LaRussa Z, Xu FM, West K, Consitt L, Davidson WS, Liu M, Coschigano KT, Shi H, Lo CC
Nutrients 2023 May 26;15(11)

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High Level of GMFG Correlated to Poor Clinical Outcome and Promoted Cell Migration and Invasion through EMT Pathway in Triple-Negative Breast Cancer.

Zhao Y, Wei X, Li J, Diao Y, Shan C, Li W, Zhang S, Wu F
Genes 2023 May 26;14(6)

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miR-199a-5p from bone marrow mesenchymal stem cell exosomes promotes the proliferation of neural stem cells by targeting GSK-3β.

Yang Y, Li Y, Zhang S, Cao L, Zhang Y, Fang B
Acta biochimica et biophysica Sinica 2023 May 25;55(5):783-794

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Rhein Inhibited Ferroptosis and EMT to Attenuate Diabetic Nephropathy by Regulating the Rac1/NOX1/β-Catenin Axis.

Xiong D, Hu W, Han X, Cai Y
Frontiers in bioscience (Landmark edition) 2023 May 25;28(5):100

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The FBXO32/ATR/ATM axis acts as a molecular switch to control the sensitivity of osteosarcoma cells to irradiation through its regulation of EXO1 expression.

Lu Y, Huang P, Li Y, Liu W, Li J, Zhao R, Feng H, Shi C, Cao G
Acta biochimica et biophysica Sinica 2023 May 24;55(5):842-852

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TMT proteomics analysis reveals the mechanism of bleomycin-induced pulmonary fibrosis and effects of Ginseng honeysuckle superfine powdered tea.

Li X, Yu X, Gao Y, Zhao W, Wang Y, Yu F, Fu C, Gao H, Cheng M, Li B
Chinese medicine 2023 May 24;18(1):60

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Ambra1 modulates the sensitivity of mantle cell lymphoma to palbociclib by regulating cyclin D1.

Jiang Z, Zhang A, Wei W, Li S
Scientific reports 2023 May 24;13(1):8389

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Hydroxysafflor yellow a confers neuroprotection against acute traumatic brain injury by modulating neuronal autophagy to inhibit NLRP3 inflammasomes.

Lai Z, Li C, Ma H, Hua S, Liu Z, Huang S, Liu K, Li J, Feng Z, Cai Y, Zou Y, Tang Y, Jiang X
Journal of ethnopharmacology 2023 May 23;308:116268

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All-Trans Retinoic Acid-Responsive LGR6 Is Transiently Expressed during Myogenic Differentiation and Is Required for Myoblast Differentiation and Fusion.

Kitakaze T, Tatsumi R, Yamaguchi M, Kubota M, Nakatsuji A, Harada N, Yamaji R
International journal of molecular sciences 2023 May 20;24(10)

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RBM10 Loss Promotes EGFR-Driven Lung Cancer and Confers Sensitivity to Spliceosome Inhibition.

Bao Y, Zhang S, Zhang X, Pan Y, Yan Y, Wang N, Ren Y, Zuo J, Zong WX, Wang Z, Wang Y
Cancer research 2023 May 2;83(9):1490-1502

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Reduced hepatic bradykinin degradation accounts for cold-induced BAT thermogenesis and WAT browning in male mice.

Xiao F, Jiang H, Li Z, Jiang X, Chen S, Niu Y, Yin H, Shu Y, Peng B, Lu W, Li X, Li Z, Lan S, Xu X, Guo F
Nature communications 2023 May 2;14(1):2523

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Epigenetically silenced lncRNA SNAI3-AS1 promotes ferroptosis in glioma via perturbing the m(6)A-dependent recognition of Nrf2 mRNA mediated by SND1.

Zheng J, Zhang Q, Zhao Z, Qiu Y, Zhou Y, Wu Z, Jiang C, Wang X, Jiang X
Journal of experimental & clinical cancer research : CR 2023 May 19;42(1):127

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Multi-omics analysis of a drug-induced model of bipolar disorder in zebrafish.

Li Y, Zhang L, Mao M, He L, Wang T, Pan Y, Zhao X, Li Z, Mu X, Qian Y, Qiu J
iScience 2023 May 19;26(5):106744

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MRPL12-ANT3 interaction involves in acute kidney injury via regulating MPTP of tubular epithelial cells.

Ji X, Chu L, Su D, Sun J, Song P, Sun S, Wang Y, Mu Q, Liu Y, Wan Q
iScience 2023 May 19;26(5):106656

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Amphibian pore-forming protein βγ-CAT drives extracellular nutrient scavenging under cell nutrient deficiency.

Liu LZ, Liu L, Shi ZH, Bian XL, Si ZR, Wang QQ, Xiang Y, Zhang Y
iScience 2023 May 19;26(5):106598

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C9ORF72 suppresses JAK-STAT mediated inflammation.

Pang W, Hu F
iScience 2023 May 19;26(5):106579

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Transcription factor Dmrt1 triggers the SPRY1-NF-κB pathway to maintain testicular immune homeostasis and male fertility.

Zhang MF, Wan SC, Chen WB, Yang DH, Liu WQ, Li BL, Aierken A, Du XM, Li YX, Wu WP, Yang XC, Wei YD, Li N, Peng S, Li XL, Li GP, Hua JL
Zoological research 2023 May 18;44(3):505-521

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Evaluation of different rat models intrauterine adhesion models and improvement of the technique for their establishment.

Xi J, Pan Y, Jin C, Liu J, Cheng J, Xu B
Experimental animals 2023 May 17;72(2):274-284

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miR-100-5p Regulates Skeletal Muscle Myogenesis through the Trib2/mTOR/S6K Signaling Pathway.

Wang K, Liufu S, Yu Z, Xu X, Ai N, Li X, Liu X, Chen B, Zhang Y, Ma H, Yin Y
International journal of molecular sciences 2023 May 17;24(10)

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Adiponectin Attenuates Splenectomy-Induced Cognitive Deficits by Neuroinflammation and Oxidative Stress via TLR4/MyD88/NF-κb Signaling Pathway in Aged Rats.

Zhang Z, Guo L, Yang F, Peng S, Wang D, Lai X, Su B, Xie H
ACS chemical neuroscience 2023 May 17;14(10):1799-1809

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The High Level of RANKL Improves IκB/p65/Cyclin D1 Expression and Decreases p-Stat5 Expression in Firm Udder of Dairy Goats.

Gao Z, Shao D, Zhao C, Liu H, Zhao X, Wei Q, Ma B
International journal of molecular sciences 2023 May 16;24(10)

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Recognition Mechanism of a Novel Gabapentinoid Drug, Mirogabalin, for Recombinant Human α(2)δ1, a Voltage-Gated Calcium Channel Subunit.

Kozai D, Numoto N, Nishikawa K, Kamegawa A, Kawasaki S, Hiroaki Y, Irie K, Oshima A, Hanzawa H, Shimada K, Kitano Y, Fujiyoshi Y
Journal of molecular biology 2023 May 15;435(10):168049

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CircPVT1 promotes ER-positive breast tumorigenesis and drug resistance by targeting ESR1 and MAVS.

Yi J, Wang L, Hu GS, Zhang YY, Du J, Ding JC, Ji X, Shen HF, Huang HH, Ye F, Liu W
The EMBO journal 2023 May 15;42(10):e112408

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Interaction of Nmi and IFP35 Promotes Mutual Protein Stabilization and IRF3 and IRF7 Degradation to Suppress Type I IFN Production in Teleost Fish.

Li L, Chen SN, Wang KL, Li N, Pang AN, Liu LH, Li B, Hou J, Wang S, Nie P
Journal of immunology (Baltimore, Md. : 1950) 2023 May 15;210(10):1494-1507

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FOXA2 plays a critical role in hepatocellular carcinoma progression and lenvatinib-associated drug resistance.

Wang Z, Shen J, Chen C, Wen T, Li C
Bioscience trends 2023 May 15;17(2):136-147

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Elevated nuclear TDP-43 induces constitutive exon skipping.

Carmen-Orozco RP, Tsao W, Ye Y, Sinha IR, Chang K, Trinh V, Chung W, Bowden K, Troncoso JC, Blackshaw S, Hayes LR, Sun S, Wong PC, Ling JP
bioRxiv : the preprint server for biology 2023 May 12;

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Structure of Semliki Forest virus in complex with its receptor VLDLR.

Cao D, Ma B, Cao Z, Zhang X, Xiang Y
Cell 2023 May 11;186(10):2208-2218.e15

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Lactiplantibacillus plantarum attenuates Coxsackievirus B3-induced pancreatitis through the BAX/BCL2/CASP3 signaling pathway.

Yu X, Zhang Y, Pei K, Tan J, Tian H, Xu T, Liu F, Peng N, Huang Y, Huang X, Huang X, Wu J, Liu Q, Zeng L, Hua W, Huang X
Food & function 2023 May 11;14(9):4129-4142

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Effect of Sublethal Concentrations of Metal Nanomaterials on Cell Energy Metabolism.

Liang C, Jiang Q, Liu Z, Yang J, Zhang J, Zhang S, Xin W
Toxics 2023 May 11;11(5)

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Interleukin-1 increases cyclooxygenase-2 expression and prostaglandin E2 production in human granulosa-lutein cell via nuclear factor kappa B/P65 and extracellular signal-regulated kinase 1/2 signaling pathways.

Wan S, Chen Q, Xiang Y, Sang Y, Tang M, Song Y, Feng G, Ye B, Bai L, Zhu Y
Molecular and cellular endocrinology 2023 May 1;566-567:111891

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Cancer-associated fibroblasts suppressed ferroptosis in glioblastoma via upregulating lncRNA DLEU1.

Zhao J, Yang S, Lv C, Liu Y
American journal of physiology. Cell physiology 2023 May 1;324(5):C1039-C1052

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EVL and MIM/MTSS1 regulate actin cytoskeletal remodeling to promote dendritic filopodia in neurons.

Parker SS, Ly KT, Grant AD, Sweetland J, Wang AM, Parker JD, Roman MR, Saboda K, Roe DJ, Padi M, Wolgemuth CW, Langlais P, Mouneimne G
The Journal of cell biology 2023 May 1;222(5)

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Soluble TREM-like Transcript-1 Acts as a Damage-Associated Molecular Pattern through the TLR4/MD2 Pathway Contributing to Immune Dysregulation during Sepsis.

Chang CM, Cheng KH, Wei TY, Lu MP, Chen YC, Lu YT
Journal of immunology (Baltimore, Md. : 1950) 2023 May 1;210(9):1351-1362

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Cardiac-specific Trim44 knockout in rat attenuates isoproterenol-induced cardiac remodeling via inhibition of AKT/mTOR pathway.

Jiang XY, Guan FF, Ma JX, Dong W, Qi XL, Zhang X, Chen W, Gao S, Gao X, Pan S, Wang JZ, Ma YW, Zhang LF, Lu D
Disease models & mechanisms 2023 May 1;16(5)

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FBXO11 amplifies type I interferon signaling to exert antiviral effects by facilitating the assemble of TRAF3-TBK1-IRF3 complex.

Gao L, Gao Y, Han K, Wang Z, Meng F, Liu J, Zhao X, Shao Y, Shen J, Sun W, Liu Y, Xu H, Du X, Li J, Qin FX
Journal of medical virology 2023 Mar;95(3):e28655

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SARS-CoV-2 Omicron XBB subvariants exhibit enhanced fusogenicity and substantial immune evasion in elderly population, but high sensitivity to pan-coronavirus fusion inhibitors.

Xia S, Jiao F, Wang L, Yu X, Lu T, Fu Y, Huang Z, Li X, Huang J, Wang Q, Man Q, Xiong L, Jiang S, Lu L
Journal of medical virology 2023 Mar;95(3):e28641

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ZNFX1 antisense RNA1 promotes antiviral innate immune responses via modulating ZNFX1 function.

Jia X, Zhang M, Wang H, Cheng C, Li Q, Li Y, Kong L, Lan X, Wang Y, Liang X, Yuan S, Wang Y, Xu A
Journal of medical virology 2023 Mar;95(3):e28637

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Ubiquitin E3 ligase β-TrCP negatively regulates surface protein of hepatitis B virus.

Tu W, Liu J, Qian F, Zhu L, Li M, Zheng H, Zhu C
Journal of medical virology 2023 Mar;95(3):e28620

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SARS-CoV-2 NSP7 inhibits type I and III IFN production by targeting the RIG-I/MDA5, TRIF, and STING signaling pathways.

Deng J, Zheng Y, Zheng SN, Nan ML, Han L, Zhang J, Jin Y, Pan JA, Gao C, Wang PH
Journal of medical virology 2023 Mar;95(3):e28561

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ATG16L1 adopts a dual-binding site mode to interact with WIPI2b in autophagy.

Gong X, Wang Y, Tang Y, Wang Y, Zhang M, Li M, Zhang Y, Pan L
Science advances 2023 Mar;9(9):eadf0824

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YY1 (Yin-Yang 1), a transcription factor regulating systemic inflammation, is involved in cognitive impairment of depression.

Lu J, Jin K, Jiao J, Liu R, Mou T, Chen B, Zhang Z, Jiang C, Zhao H, Wang Z, Zhou R, Huang M
Psychiatry and clinical neurosciences 2023 Mar;77(3):149-159

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A Disintegrin and Metalloproteinase 10 (ADAM10) Is Essential for Oligodendrocyte Precursor Development and Myelination in the Mouse Brain.

Guo D, Huang F, Xue R, Ma Y, Xiao L, Lou H, Pan S
Molecular neurobiology 2023 Mar;60(3):1675-1689

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An unconventional cancer-promoting function of methamphetamine in hepatocellular carcinoma.

Si Z, Yang G, Wang X, Yu Z, Pang Q, Zhang S, Qian L, Ruan Y, Huang J, Yu L
Life science alliance 2023 Mar;6(3)

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GBP2 promotes clear cell renal cell carcinoma progression through immune infiltration and regulation of PD‑L1 expression via STAT1 signaling.

Ye S, Li S, Qin L, Zheng W, Liu B, Li X, Ren Z, Zhao H, Hu X, Ye N, Li G
Oncology reports 2023 Mar;49(3)

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Effects of icariin and curcumol on autophagy, ferroptosis, and lipid metabolism based on miR-7/m-TOR/SREBP1 pathway on prostate cancer.

Xu W, Ding J, Li B, Sun T, You X, He Q, Sheng W
BioFactors (Oxford, England) 2023 Mar;49(2):438-456

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Methionine sulfoxide suppresses adipogenic differentiation by regulating the mitogen-activated protein kinase signaling pathway.

Qin D, Lei Y, Xie W, Zheng Q, Peng Z, Liu Y, Dai B, Ma T, Wei P, Gao C, Guo X, Gao J, Zhao J, Du J, Zeng Q, Zhang Z, Dong X, Shen H
Cell biology international 2023 Mar;47(3):648-659

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RASSF1A inhibits epithelial-mesenchymal transition of gastric cancer cells by downregulating P-JNK.

Bin Y, Deng W, Hu H, Zeng Q, Chen J, Xu Y, Dai Y, Liao A, Xiao W
Cell biology international 2023 Mar;47(3):573-583

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Ginsenoside compound K reduces ischemia/reperfusion-induced neuronal apoptosis by inhibiting PTP1B-mediated IRS1 tyrosine dephosphorylation.

Fu J, Yu L, Yu Q, Yu N, Xu F, Li S
Journal of ginseng research 2023 Mar;47(2):274-282

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p52-ZER6: a determinant of tumor cell sensitivity to MDM2-p53 binding inhibitors.

Li WF, Alfason L, Huang C, Tang Y, Qiu L, Miyagishi M, Wu SR, Kasim V
Acta pharmacologica Sinica 2023 Mar;44(3):647-660

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The E3 ligase RBCK1 reduces the sensitivity of ccRCC to sunitinib through the ANKRD35-MITD1-ANXA1 axis.

Wang Y, Peng M, Zhong Y, Xiong W, Zhu L, Jin X
Oncogene 2023 Mar;42(13):952-966

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hASCs-derived exosomal miR-155-5p targeting TGFβR2 promotes autophagy and reduces pyroptosis to alleviate intervertebral disc degeneration.

Chen D, Jiang X, Zou H
Journal of orthopaedic translation 2023 Mar;39:163-176

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Cerebrospinal fluid-derived extracellular vesicles after spinal cord injury promote vascular regeneration via PI3K/AKT signaling pathway.

Li C, Qin T, Jin Y, Hu J, Yuan F, Cao Y, Duan C
Journal of orthopaedic translation 2023 Mar;39:124-134

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Linear ubiquitination of LKB1 activates AMPK pathway to inhibit NLRP3 inflammasome response and reduce chondrocyte pyroptosis in osteoarthritis.

Chen Y, Liu Y, Jiang K, Wen Z, Cao X, Wu S
Journal of orthopaedic translation 2023 Mar;39:1-11

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miR-124-3p improves mitochondrial function of renal tubular epithelial cells in db/db mice.

Liang L, Wo C, Yuan Y, Cao H, Tan W, Zhou X, Wang D, Chen R, Shi M, Zhang F, Xiao Y, Liu L, Zhou Y, Zhang T, Wang Y, Guo B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22794

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A Physiologically Responsive Nanocomposite Hydrogel for Treatment of Head and Neck Squamous Cell Carcinoma via Proteolysis-Targeting Chimeras Enhanced Immunotherapy.

Wu Y, Chang X, Yang G, Chen L, Wu Q, Gao J, Tian R, Mu W, Gooding JJ, Chen X, Sun S
Advanced materials (Deerfield Beach, Fla.) 2023 Mar;35(12):e2210787

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HSP90β promotes osteoclastogenesis by dual-activation of cholesterol synthesis and NF-κB signaling.

Cheng HM, Xing M, Zhou YP, Zhang W, Liu Z, Li L, Zheng Z, Ma Y, Li P, Liu X, Li P, Xu X
Cell death and differentiation 2023 Mar;30(3):673-686

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Glioblastoma glycolytic signature predicts unfavorable prognosis, immunological heterogeneity, and ENO1 promotes microglia M2 polarization and cancer cell malignancy.

Liang X, Wang Z, Dai Z, Zhang H, Zhang J, Luo P, Liu Z, Liu Z, Yang K, Cheng Q, Zhang M
Cancer gene therapy 2023 Mar;30(3):481-496

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Transcription factor SOX15 regulates stem cell pluripotency and promotes neural fate during differentiation by activating the neurogenic gene Hes5.

Choi EB, Vodnala M, Saini P, Anugula S, Zerbato M, Ho JJ, Wang J, Ho Sui SJ, Yoon J, Roels M, Inouye C, Fong YW
The Journal of biological chemistry 2023 Mar;299(3):102996

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USP22 suppresses the NLRP3 inflammasome by degrading NLRP3 via ATG5-dependent autophagy.

Di Q, Zhao X, Tang H, Li X, Xiao Y, Wu H, Wu Z, Quan J, Chen W
Autophagy 2023 Mar;19(3):873-885

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SDC1-dependent TGM2 determines radiosensitivity in glioblastoma by coordinating EPG5-mediated fusion of autophagosomes with lysosomes.

Zheng W, Chen Q, Liu H, Zeng L, Zhou Y, Liu X, Bai Y, Zhang J, Pan Y, Shao C
Autophagy 2023 Mar;19(3):839-857

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Liraglutide abrogates nephrotoxic effects of chemotherapies.

Xu C, Lu C, Wang Z, Hu X, Li S, Xie Y, Qiu Y, Cao R, Li Y, Yang J
Pharmacological research 2023 Mar;189:106680

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Chronic spinal cord compression associated with intervertebral disc degeneration in SPARC-null mice.

Li ZY, Zhou AF, Li G, Zhou LY, Pu PM, Zhu K, Zheng Z, Wang YJ, Liang QQ, Yao M, Cui XJ
Neural regeneration research 2023 Mar;18(3):634-642

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Ectopic endometriotic stromal cells-derived lactate induces M2 macrophage polarization via Mettl3/Trib1/ERK/STAT3 signalling pathway in endometriosis.

Gou Y, Wang H, Wang T, Wang H, Wang B, Jiao N, Yu Y, Cao Y, Wang H, Zhang Z
Immunology 2023 Mar;168(3):389-402

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The Effect of Gut Microbiota on the Progression of Intervertebral Disc Degeneration.

Yao B, Cai Y, Wang W, Deng J, Zhao L, Han Z, Wan L
Orthopaedic surgery 2023 Mar;15(3):858-867

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Hesperidin enhances intestinal barrier function in Caco-2 cell monolayers via AMPK-mediated tight junction-related proteins.

Park HY, Yu JH
FEBS open bio 2023 Mar;13(3):532-544

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Thioredoxin 1 overexpression attenuated diabetes-induced endoplasmic reticulum stress in Müller cells via apoptosis signal-regulating kinase 1.

Yu X, Teng Q, Bao K, Chudhary M, Qi H, Zhou W, Che H, Liu J, Ren X, Kong L
Journal of cellular biochemistry 2023 Mar;124(3):421-433

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Antidepressant-like effect of CP-101,606: Evidence of mTOR pathway activation.

Qin Y, Guo X, Song W, Liang Z, Wang Y, Feng D, Yang Y, Li M, Gao M
Molecular and cellular neurosciences 2023 Mar;124:103821

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Metabolism-related lncRNAs signature to predict the prognosis of colon adenocarcinoma.

Sun Y, Liu B, Xiao B, Jiang X, Xiang JJ, Xie J, Hu XM
Cancer medicine 2023 Mar;12(5):5994-6008

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Developmental changes in lipid and fatty acid metabolism and the inhibition by in ovo feeding oleic acid in Muscovy duck embryogenesis.

Zhang X, Wu Q, Zheng W, Liu C, Huang L, Zuo X, Xiao W, Han X, Ye H, Wang W, Yang L, Zhu Y
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2023 Mar;12:321-333

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Lin28a induced mitochondrial dysfunction in human granulosa cells via suppressing LARS2 expression.

Chen J, Liu W
Cellular signalling 2023 Mar;103:110536

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Guanylate-binding protein 1 restricts avian coronavirus infectious bronchitis virus-infected HD11 cells.

Ma P, Gu K, Wen R, Li C, Zhou C, Zhao Y, Li H, Lei C, Yang X, Wang H
Poultry science 2023 Mar;102(3):102398

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Uridine Alleviates Sepsis-Induced Acute Lung Injury by Inhibiting Ferroptosis of Macrophage.

Lai K, Song C, Gao M, Deng Y, Lu Z, Li N, Geng Q
International journal of molecular sciences 2023 Mar 7;24(6)

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p53 directly downregulates the expression of CDC20 to exert anti-tumor activity in mantle cell lymphoma.

Chen Y, Yang P, Wang J, Gao S, Xiao S, Zhang W, Zhu M, Wang Y, Ke X, Jing H
Experimental hematology & oncology 2023 Mar 7;12(1):28

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Effects of Caprylic Acid and Eicosapentaenoic Acid on Lipids, Inflammatory Levels, and the JAK2/STAT3 Pathway in ABCA1-Deficient Mice and ABCA1 Knock-Down RAW264.7 Cells.

Zhang X, Zhang P, Liu Y, Liu Z, Xu Q, Zhang Y, Liu L, Yang X, Li L, Xue C
Nutrients 2023 Mar 6;15(5)

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Isopropyl 3-(3, 4-dihydroxyphenyl)-2-hydroxypropanoate protects lipopolysaccharide-induced acute lung injury in mice by attenuating pyroptosis.

Zhang ML, Wang M, Chen J, Liu YJ, Yu YJ, Liu LM, Zheng XH, Xiao YC, Zhang JM, Zhu MX, Yue X, Zhao Y, Niu W, Li ZC
European journal of pharmacology 2023 Mar 5;942:175545

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Sertaconazole nitrate targets IDO1 and regulates the MAPK signaling pathway to induce autophagy and apoptosis in CRC cells.

Yang Y, Jin Y, Yin L, Liu P, Zhu L, Gao H
European journal of pharmacology 2023 Mar 5;942:175515

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PKM2/PDK1 dual-targeted shikonin derivatives restore the sensitivity of EGFR-mutated NSCLC cells to gefitinib by remodeling glucose metabolism.

Lin H, Han H, Yang M, Wen Z, Chen Q, Ma Y, Wang X, Wang C, Yin T, Wang X, Lu G, Chen H, Qi J, Yang Y
European journal of medicinal chemistry 2023 Mar 5;249:115166

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DNA repair mechanisms that promote insertion-deletion events during immunoglobulin gene diversification.

Hao Q, Zhan C, Lian C, Luo S, Cao W, Wang B, Xie X, Ye X, Gui T, Voena C, Pighi C, Wang Y, Tian Y, Wang X, Dai P, Cai Y, Liu X, Ouyang S, Sun S, Hu Q, Liu J, Ye Y, Zhao J, Lu A, Wang JY, Huang C, Su B, Meng FL, Chiarle R, Pan-Hammarström Q, Yeap LS
Science immunology 2023 Mar 31;8(81):eade1167

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miR-19a-3p affected ox-LDL-induced SDC-1/TGF-β1/Smad3 pathway in atherosclerosis.

Jin Q, Deng Y, Li L, Chen R, Jiang L
Cellular and molecular biology (Noisy-le-Grand, France) 2023 Mar 31;69(3):75-81

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The stromal-tumor amplifying STC1-Notch1 feedforward signal promotes the stemness of hepatocellular carcinoma.

Bai S, Zhao Y, Chen W, Peng W, Wang Y, Xiong S, Aruna, Li Y, Yang Y, Chen S, Cheng B, Wang R
Journal of translational medicine 2023 Mar 31;21(1):236

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Ferredoxin 1 regulates granulosa cell apoptosis and autophagy in polycystic ovary syndrome.

Xing J, Qiao G, Luo X, Liu S, Chen S, Ye G, Zhang C, Yi J
Clinical science (London, England : 1979) 2023 Mar 31;137(6):453-468

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Sustainably released nanoparticle-based rhynchophylline limits pulmonary fibrosis by inhibiting the TEK-PI3K/AKT signaling pathway.

Wang S, Huang Z, Liu Y, Sun H, Zhou Y, Shi J
Translational lung cancer research 2023 Mar 31;12(3):427-445

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9-Butyl-Harmol Exerts Antiviral Activity against Newcastle Disease Virus through Targeting GSK-3β and HSP90β.

Wang C, Wang T, Hu R, Duan L, Hou Q, Han Y, Dai J, Wang W, Ren S, Liu H, Wang X, Xiao S, Li N, Wang J, Yang Z
Journal of virology 2023 Mar 30;97(3):e0198422

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All Domains of SARS-CoV-2 nsp1 Determine Translational Shutoff and Cytotoxicity of the Protein.

Frolov I, Agback T, Palchevska O, Dominguez F, Lomzov A, Agback P, Frolova EI
Journal of virology 2023 Mar 30;97(3):e0186522

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Newcastle Disease Virus Manipulates Mitochondrial MTHFD2-Mediated Nucleotide Metabolism for Virus Replication.

Tang N, Chen P, Zhao C, Liu P, Tan L, Song C, Qiu X, Liao Y, Liu X, Luo T, Sun Y, Ding C
Journal of virology 2023 Mar 30;97(3):e0001623

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Theabrownin Isolated from Pu-Erh Tea Enhances the Innate Immune and Anti-Inflammatory Effects of RAW264.7 Macrophages via the TLR2/4-Mediated Signaling Pathway.

Zhao L, Miao Y, Shan B, Zhao C, Peng C, Gong J
Foods (Basel, Switzerland) 2023 Mar 30;12(7)

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RPL11 promotes non-small cell lung cancer cell proliferation by regulating endoplasmic reticulum stress and cell autophagy.

Chen J, Lei C, Zhang H, Huang X, Yang Y, Liu J, Jia Y, Shi H, Zhang Y, Zhang J, Du J
BMC molecular and cell biology 2023 Mar 3;24(1):7

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PVT1/miR-136/Sox2/UPF1 axis regulates the malignant phenotypes of endometrial cancer stem cells.

Li Q, Kong F, Cong R, Ma J, Wang C, Ma X
Cell death & disease 2023 Mar 3;14(3):177

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Comprehensive proteogenomic characterization of early duodenal cancer reveals the carcinogenesis tracks of different subtypes.

Li L, Jiang D, Liu H, Guo C, Zhao R, Zhang Q, Xu C, Qin Z, Feng J, Liu Y, Wang H, Chen W, Zhang X, Li B, Bai L, Tian S, Tan S, Yu Z, Chen L, Huang J, Zhao JY, Hou Y, Ding C
Nature communications 2023 Mar 29;14(1):1751

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A new ferrocene derivative blocks KRAS localization and function by oxidative modification at His95.

Rehl KM, Selvakumar J, Hoang D, Arumugam K, Gorfe AA, Cho KJ
bioRxiv : the preprint server for biology 2023 Mar 29;

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Baicalin facilitates remyelination and suppresses neuroinflammation in rats with chronic cerebral hypoperfusion by activating Wnt/β-catenin and inhibiting NF-κB signaling.

Xiao Y, Guan T, Yang X, Xu J, Zhang J, Qi Q, Teng Z, Dong Y, Gao Y, Li M, Meng N, Lv P
Behavioural brain research 2023 Mar 28;442:114301

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Role of Berberine Thermosensitive Hydrogel in Periodontitis via PI3K/AKT Pathway In Vitro.

Wang C, Liu C, Liang C, Qu X, Zou X, Du S, Zhang Q, Wang L
International journal of molecular sciences 2023 Mar 28;24(7)

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PARM1 Drives Smooth Muscle Cell Proliferation in Pulmonary Arterial Hypertension via AKT/FOXO3A Axis.

He Z, Chang T, Chen Y, Wang H, Dai L, Zeng H
International journal of molecular sciences 2023 Mar 28;24(7)

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Identification of biomarkers of hepatocellular carcinoma gene prognosis based on the immune-related lncRNA signature of transcriptome data.

Ma A, Sun Y, Ogbodu RO, Xiao L, Deng H, Zhou H
Functional & integrative genomics 2023 Mar 28;23(2):104

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Hyperglycemia induces PFKFB3 overexpression and promotes malignant phenotype of breast cancer through RAS/MAPK activation.

Cheng X, Jia X, Wang C, Zhou S, Chen J, Chen L, Chen J
World journal of surgical oncology 2023 Mar 28;21(1):112

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CD137 signaling aggravates myocardial ischemia-reperfusion injury by inhibiting mitophagy mediated NLRP3 inflammasome activation.

Zang GY, Yin Q, Shao C, Sun Z, Zhang LL, Xu Y, Li LH, Wang ZQ
Journal of geriatric cardiology : JGC 2023 Mar 28;20(3):223-237

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Downregulated annexin A1 expression correlates with poor prognosis, metastasis, and immunosuppressive microenvironment in Ewing's sarcoma.

Shi X, Wu Y, Tang L, Ni H, Xu Y
Aging 2023 Mar 28;15(6):2321-2346

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Microglial aryl hydrocarbon receptor enhances phagocytic function via SYK and promotes remyelination in the cuprizone mouse model of demyelination.

Wang Y, Sun J, Zhu K, Wang D, Zhao X, Zhang H, Wu S, Wang Y, Wang J
Journal of neuroinflammation 2023 Mar 25;20(1):83

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FZD7, Regulated by Non-CpG Methylation, Plays an Important Role in Immature Porcine Sertoli Cell Proliferation.

Yang A, Yan S, Yin Y, Chen C, Tang X, Ran M, Chen B
International journal of molecular sciences 2023 Mar 24;24(7)

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The rhythmic coupling of Egr-1 and Cidea regulates age-related metabolic dysfunction in the liver of male mice.

Wu J, Bu D, Wang H, Shen D, Chong D, Zhang T, Tao W, Zhao M, Zhao Y, Fang L, Li P, Xue B, Li CJ
Nature communications 2023 Mar 24;14(1):1634

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Podocyte-specific deletion of ubiquitin carboxyl-terminal hydrolase L1 causes podocyte injury by inducing endoplasmic reticulum stress.

Hu Y, Qi C, Shi J, Tan W, Adiljan Abdurusul, Zhao Z, Xu Y, Wu H, Zhang Z
Cellular and molecular life sciences : CMLS 2023 Mar 23;80(4):106

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The OTUD1-Notch2-ICD axis orchestrates allogeneic T cell-mediated graft-versus-host disease.

Cheng Q, Wang D, Lai X, Liu Y, Zuo Y, Zhang W, Lei L, Chen J, Liu H, Wang Y, Liu H, Zheng H, Wu D, Xu Y
Blood 2023 Mar 23;141(12):1474-1488

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p38-mediated FOXN3 phosphorylation modulates lung inflammation and injury through the NF-κB signaling pathway.

Zhu X, Huang B, Zhao F, Lian J, He L, Zhang Y, Ji L, Zhang J, Yan X, Zeng T, Ma C, Liang Y, Zhang C, Lin J
Nucleic acids research 2023 Mar 21;51(5):2195-2214

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Activating mitofusins interrupts mitochondrial degeneration and delays disease progression in SOD1 mutant amyotrophic lateral sclerosis.

Dang X, Zhang L, Franco A, Dorn Ii GW
Human molecular genetics 2023 Mar 20;32(7):1208-1222

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Prediction and Verification of Curcumin as a Potential Drug for Inhibition of PDCoV Replication in LLC-PK1 Cells.

Wang X, Wang X, Zhang J, Shan Q, Zhu Y, Xu C, Wang J
International journal of molecular sciences 2023 Mar 20;24(6)

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TUBA1C: a new potential target of LncRNA EGFR-AS1 promotes gastric cancer progression.

Wang H, Cui H, Yang X, Peng L
BMC cancer 2023 Mar 20;23(1):258

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Dietary choline metabolite TMAO impairs cognitive function and induces hippocampal synaptic plasticity declining through the mTOR/P70S6K/4EBP1 pathway.

Zhou S, Liu J, Sun Y, Xu P, Liu JL, Sun S, Zhu B, Wu H
Food & function 2023 Mar 20;14(6):2881-2895

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Aberrant Activation of the STING-TBK1 Pathway in γδ T Cells Regulates Immune Responses in Oral Lichen Planus.

Huang S, Tan YQ, Zhou G
Biomedicines 2023 Mar 20;11(3)

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Secreted protease PRSS35 suppresses hepatocellular carcinoma by disabling CXCL2-mediated neutrophil extracellular traps.

Wang T, Zhou Y, Zhou Z, Zhang P, Yan R, Sun L, Ma W, Zhang T, Shen S, Liu H, Lu H, Ye L, Feng J, Chen Z, Zhong X, Wu G, Cai Y, Jia W, Gao P, Zhang H
Nature communications 2023 Mar 18;14(1):1513

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An XBP1s-PIM-2 positive feedback loop controls IL-15-mediated survival of natural killer cells.

Ma S, Han J, Li Z, Xiao S, Zhang J, Yan J, Tang T, Barr T, Kraft AS, Caligiuri MA, Yu J
Science immunology 2023 Mar 17;8(81):eabn7993

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PPT1 regulation of HSP90α depalmitoylation participates in the pathogenesis of hyperandrogenism.

Xue T, Zhao S, Zhang H, Tang T, Zheng L, Jing J, Ge X, Ma R, Ma J, Ren X, Jueraitetibaike K, Guo Z, Chen L, Yao B
iScience 2023 Mar 17;26(3):106131

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Hsp22 pretreatment protects against LPS-induced hippocampal injury by alleviating neuroinflammation and apoptosis by regulating the NLRP3/Caspase1/IL-1β signaling pathway in mice.

Peng S, Yu Y, Li J, Jiang D, Xu G, Wu L, Hu J
Aging 2023 Mar 17;15(6):1977-2004

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SIM imaging resolves endocytosis of SARS-CoV-2 spike RBD in living cells.

Miao L, Yan C, Chen Y, Zhou W, Zhou X, Qiao Q, Xu Z
Cell chemical biology 2023 Mar 16;30(3):248-260.e4

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Efficient tumor synergistic chemoimmunotherapy by self-augmented ROS-responsive immunomodulatory polymeric nanodrug.

Song J, Cheng M, Xie Y, Li K, Zang X
Journal of nanobiotechnology 2023 Mar 16;21(1):93

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DnaJC7 specifically regulates tau seeding.

Perez VA, Sanders DW, Mendoza-Oliva A, Stopschinski BE, Mullapudi V, White CL 3rd, Joachimiak LA, Diamond MI
bioRxiv : the preprint server for biology 2023 Mar 16;

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Proteome profiling of the prefrontal cortex of Fmr1 knockout mouse reveals enhancement of complement and coagulation cascades.

Gao MM, Shi H, Yan HJ, Long YS
Journal of proteomics 2023 Mar 15;274:104822

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RIG-I Promotes Tumorigenesis and Confers Radioresistance of Esophageal Squamous Cell Carcinoma by Regulating DUSP6.

Li L, Lv L, Xu JC, He Q, Chang N, Cui YY, Tao ZC, Zhu T, Qian LT
International journal of molecular sciences 2023 Mar 15;24(6)

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Combination therapy with ultrasound and 2D nanomaterials promotes recovery after spinal cord injury via Piezo1 downregulation.

Zhang F, He X, Dong K, Yang L, Ma B, Liu Y, Liu Z, Chen B, Zhu R, Cheng L
Journal of nanobiotechnology 2023 Mar 15;21(1):91

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CENP-I directly targets centromeric DNA to support CENP-A deposition and centromere maintenance.

Hu L, Zhao C, Liu M, Liu S, Ye J, Wang K, Shi J, Tian W, He X
Proceedings of the National Academy of Sciences of the United States of America 2023 Mar 14;120(11):e2219170120

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IFIT2 Depletion Promotes Cancer Stem Cell-like Phenotypes in Oral Cancer.

Lai KC, Regmi P, Liu CJ, Lo JF, Lee TC
Biomedicines 2023 Mar 14;11(3)

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A novel cuproptosis-related gene signature to predict prognosis in Glioma.

Zhang M, Liu X, Wang D, Ruan X, Wang P, Liu L, Xue Y
BMC cancer 2023 Mar 13;23(1):237

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Adipocyte YTH N(6)-methyladenosine RNA-binding protein 1 protects against obesity by promoting white adipose tissue beiging in male mice.

Yan S, Zhou X, Wu C, Gao Y, Qian Y, Hou J, Xie R, Han B, Chen Z, Wei S, Gao X
Nature communications 2023 Mar 13;14(1):1379

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CCP1, a Regulator of Tubulin Post-Translational Modifications, Potentially Plays an Essential Role in Cerebellar Development.

Pang B, Araki A, Zhou L, Takebayashi H, Harada T, Kadota K
International journal of molecular sciences 2023 Mar 10;24(6)

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Canagliflozin ameliorates the development of NAFLD by preventing NLRP3-mediated pyroptosis through FGF21-ERK1/2 pathway.

Huang S, Wu B, He Y, Qiu R, Yang T, Wang S, Lei Y, Li H, Zheng F
Hepatology communications 2023 Mar 1;7(3):e0045

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The Qi-Bang-Yi-Shen formula ameliorates renal dysfunction and fibrosis in rats with diabetic kidney disease via regulating PI3K/AKT, ERK and PPARγ signaling pathways.

Wang Z, Jian G, Chen T, Chen Y, Li J, Wang N
European journal of histochemistry : EJH 2023 Mar 1;67(1)

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Pinellia ternata lectin induces inflammation through TLR4 receptor and mediates PI3K/Akt/mTOR axis to regulate NF-κB signaling pathway.

Li J, Wang W, Yuan Y, Cui X, Bian H, Wen H, Zhang X, Yu H, Wu H
Toxicology 2023 Mar 1;486:153430

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Effects and mechanisms of Xiaochaihu Tang against liver fibrosis: An integration of network pharmacology, molecular docking and experimental validation.

Wang SJ, Ye W, Li WY, Tian W, Zhang M, Sun Y, Feng YD, Liu CX, Liu SY, Cao W, Meng JR, Li XQ
Journal of ethnopharmacology 2023 Mar 1;303:116053

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Exploring the potential of ginseng glycoprotein to improve learning and memory in mice via Notch signaling pathway and structural analysis using multi-information fusion based on liquid chromatography-mass spectrometry.

Fang X, Zhang X, Zhang Y, Zhang X, Shan M, Guan S, Qiu Z, Zhu D, Luo H
Journal of ethnopharmacology 2023 Mar 1;303:115978

---

Identification of menaquinone-4 (vitamin K2) target genes in bovine endometrial epithelial cells in vitro.

Bai H, Kawahara M, Takahashi M
Theriogenology 2023 Mar 1;198:183-193

---

Gold nanoparticles inhibit tumor growth via targeting the Warburg effect in a c-Myc-dependent way.

Sun L, Liu Y, Yang N, Ye X, Liu Z, Wu J, Zhou M, Zhong W, Cao M, Zhang J, Mequanint K, Xing M, Liao W
Acta biomaterialia 2023 Mar 1;158:583-598

---

TP63 gain-of-function mutations cause premature ovarian insufficiency by inducing oocyte apoptosis.

Huang C, Zhao S, Yang Y, Guo T, Ke H, Mi X, Qin Y, Chen ZJ, Zhao S
The Journal of clinical investigation 2023 Mar 1;133(5)

---

CRISPR/Cas9 screen uncovers functional translation of cryptic lncRNA-encoded open reading frames in human cancer.

Zheng C, Wei Y, Zhang P, Xu L, Zhang Z, Lin K, Hou J, Lv X, Ding Y, Chiu Y, Jain A, Islam N, Malovannaya A, Wu Y, Ding F, Xu H, Sun M, Chen X, Chen Y
The Journal of clinical investigation 2023 Mar 1;133(5)

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SARS-CoV-2 NSP13 interacts with host IRF3, blocking antiviral immune responses.

Feng K, Zhang HJ, Min YQ, Zhou M, Deng F, Wang HL, Li PQ, Ning YJ
Journal of medical virology 2023 Jun;95(6):e28881

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TMEM2 induces epithelial-mesenchymal transition and promotes resistance to temozolomide in GBM cells.

Gao L, Tong S, Liu J, Cai J, Ye Z, Zhou L, Song P, Li Z, Lei P, Wei H, Hua Q, Tian D, Cai Q
Heliyon 2023 Jun;9(6):e16559

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Glutaredoxin 1 protects lens epithelial cells from epithelial-mesenchymal transition by preventing casein kinase 1α S-glutathionylation during posterior capsular opacification.

Li C, Chen X, Zhang S, Liang C, Ma X, Zhang R, Yan H
Redox biology 2023 Jun;62:102676

---

Exercise improves homeostasis of the intestinal epithelium by activation of apelin receptor-AMP-activated protein kinase signalling.

Chae SA, Du M, Son JS, Zhu MJ
The Journal of physiology 2023 Jun;601(12):2371-2389

---

Dysfunction of NRG1/ErbB4 Signaling in the Hippocampus Might Mediate Long-term Memory Decline After Systemic Inflammation.

Gao YZ, Wu XM, Zhou ZQ, Liu PM, Yang JJ, Ji MH
Molecular neurobiology 2023 Jun;60(6):3210-3226

---

The YTHDC1/GLUT3/RNF183 axis forms a positive feedback loop that modulates glucose metabolism and bladder cancer progression.

Yan B, Li X, Peng M, Zuo Y, Wang Y, Liu P, Ren W, Jin X
Experimental & molecular medicine 2023 Jun;55(6):1145-1158

---

ARID3A plays a key regulatory role in palmitic acid-stimulated milk fat synthesis in mouse mammary epithelial cells.

Guo X, Qi H, Lin G, Yu J, Zhang M, Gao X
Cell biology international 2023 Jun;47(6):1106-1117

---

TLR2-mediated NF-κB signaling pathway is involved in PPV1-induced apoptosis in PK-15 cells.

Xu M, Jin X, Zhang C, Liao H, Wang P, Zhou Y, Song Y, Xia L, Wang L
Veterinary research communications 2023 Jun;47(2):397-407

---

Chlorogenic Acid Alleviates Hepatic Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress, Inflammation, and Mitochondria-Mediated Apoptosis In Vivo and In Vitro.

Li K, Feng Z, Wang L, Ma X, Wang L, Liu K, Geng X, Peng C
Inflammation 2023 Jun;46(3):1061-1076

---

Thioredoxin-1 regulates IRE1α to ameliorate sepsis-induced NLRP3 inflammasome activation and oxidative stress in Raw 264.7 cell.

Shao R, Lou X, Xue J, Yang Y, Ning D, Chen G, Jiang L
Immunopharmacology and immunotoxicology 2023 Jun;45(3):277-286

---

Tabersonine, a natural NLRP3 inhibitor, suppresses inflammasome activation in macrophages and attenuate NLRP3-driven diseases in mice.

Xu HW, Li WF, Hong SS, Shao JJ, Chen JH, Chattipakorn N, Wu D, Luo W, Liang G
Acta pharmacologica Sinica 2023 Jun;44(6):1252-1261

---

Quantitative proteomics of sperm tail in asthenozoospermic patients: exploring the molecular pathways affecting sperm motility.

Mirshahvaladi S, Topraggaleh TR, Bucak MN, Rahimizadeh P, Shahverdi A
Cell and tissue research 2023 Jun;392(3):793-810

---

Hawthorn fruit extract protect against MC-LR-induced hepatotoxicity by attenuating oxidative stress and apoptosis.

Wang Y, Guo Y, Liu H, Du X, Shi L, Wang W, Zhang S
Environmental toxicology 2023 Jun;38(6):1239-1250

---

A novel nano material for anti-cerebral ischaemia: preparation and application of borneol angelica polysaccharide liposomes.

Ding H, Wang K, He LQ, Yang XY, Huang HH, Liu WL, Xiao C, Du ZX, Yu L, Zhang W
Journal of liposome research 2023 Jun;33(2):144-153

---

Loss of exosomal miR-200b-3p from hypoxia cancer-associated fibroblasts promotes tumorigenesis and reduces sensitivity to 5-Flourouracil in colorectal cancer via upregulation of ZEB1 and E2F3.

Gong W, Guo Y, Yuan H, Chai R, Wan Z, Zheng B, Hu X, Chen B, Gao S, Dai Q, Yu P, Tu S
Cancer gene therapy 2023 Jun;30(6):905-916

---

A Genome-Wide Association Study for Susceptibility to Axial Length in Highly Myopic Eyes.

Lu Q, Du Y, Zhang Y, Chen Y, Li H, He W, Tang Y, Zhao Z, Zhang Y, Wu J, Zhu X, Lu Y
Phenomics (Cham, Switzerland) 2023 Jun;3(3):255-267

---

Oculocerebrorenal syndrome of Lowe (OCRL) controls leukemic T-cell survival by preventing excessive PI(4,5)P(2) hydrolysis in the plasma membrane.

Chen H, Lu C, Tan Y, Weber-Boyvat M, Zheng J, Xu M, Xiao J, Liu S, Tang Z, Lai C, Li M, Olkkonen VM, Yan D, Zhong W
The Journal of biological chemistry 2023 Jun;299(6):104812

---

Disruption of the ADAM17/NF-κB feedback loop in astrocytes ameliorates HIV-1 Tat-induced inflammatory response and neuronal death.

Qiu X, Wang J, Zhang W, Duan C, Chen T, Zhang D, Su J, Gao L
Journal of neurovirology 2023 Jun;29(3):283-296

---

Baicalin and baicalein attenuate hyperuricemic nephropathy via inhibiting PI3K/AKT/NF-κB signalling pathway.

Liu Z, Xiang H, Deng Q, Fu W, Li Y, Yu Z, Qiu Y, Mei Z, Xu L
Nephrology (Carlton, Vic.) 2023 Jun;28(6):315-327

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Donor graft METTL3 gene transfer ameliorates rat liver transplantation ischemia-reperfusion injury by enhancing HO-1 expression in an m(6)A-dependent manner.

Xiang S, Wang Y, Lei D, Luo Y, Peng D, Zong K, Liu Y, Huang Z, Mo S, Pu X, Zheng J, Wu Z
Clinical immunology (Orlando, Fla.) 2023 Jun;251:109325

---

BACH1 promotes intervertebral disc degeneration by regulating HMOX1/GPX4 to mediate oxidative stress, ferroptosis, and lipid metabolism in nucleus pulposus cells.

Yao B, Cai Y, Wan L, Deng J, Zhao L, Wang W, Han Z
The journal of gene medicine 2023 Jun;25(6):e3488

---

Silencing of FAM111B inhibits tumor growth and promotes apoptosis by decreasing AKT activity in ovarian cancer.

Wang W, Gu Y, Ni H, Quan Q, Guo L
Experimental biology and medicine (Maywood, N.J.) 2023 Jun;248(12):1043-1055

---

Upregulation of CSNK1A1 induced by ITGB5 confers to hepatocellular carcinoma resistance to sorafenib in vivo by disrupting the EPS15/EGFR complex.

Gu L, Jin X, Liang H, Yang C, Zhang Y
Pharmacological research 2023 Jun;192:106789

---

Charged multivesicular body protein 2B ameliorates biliary injury in the liver from donation after cardiac death rats via autophagy with air-oxygenated normothermic machine perfusion.

Bai Y, Shi JH, Liu Q, Yang DJ, Yan ZP, Zhang JK, Tang HW, Guo WZ, Jin Y, Zhang SJ
Biochimica et biophysica acta. Molecular basis of disease 2023 Jun;1869(5):166686

---

Discovery of alantolactone as a naturally occurring NLRP3 inhibitor to alleviate NLRP3-driven inflammatory diseases in mice.

Li W, Xu H, Shao J, Chen J, Lin Y, Zheng Z, Wang Y, Luo W, Liang G
British journal of pharmacology 2023 Jun;180(12):1634-1647

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Ginsenoside Rb1 improves energy metabolism after spinal cord injury.

Wen S, Zou ZR, Cheng S, Guo H, Hu HS, Zeng FZ, Mei XF
Neural regeneration research 2023 Jun;18(6):1332-1338

---

An integrated strategy combining network toxicology and feature-based molecular networking for exploring hepatotoxic constituents and mechanism of Epimedii Folium-induced hepatotoxicity in vitro.

Zhao Z, Du JF, Wang QL, Qiu FN, Chen XY, Liu FJ, Li P, Jiang Y, Li HJ
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jun;176:113785

---

MiR-5622-3p inhibits ZCWPW1 to induce apoptosis in silica-exposed mice and spermatocyte cells.

Zhao M, Zhou G, Wang J, Zhang Y, Xue J, Liu J, Xie J, Ren L, Zhou X
Nanotoxicology 2023 Jun;17(4):372-384

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Baicalin ameliorates multidrug-resistant Pseudomonas aeruginosa induced pulmonary inflammation in rat via arginine biosynthesis.

Li L, Cui H, Zhang Y, Xie W, Lin Y, Guo Y, Huang T, Xue B, Guo W, Huang Z, Man T, Yu H, Zhai Z, Cheng M, Wang M, Lei H, Wang C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114660

---

NPTX2 Promotes Epithelial-Mesenchymal Transition in Cutaneous Squamous Cell Carcinoma through METTL3-Mediated N6-Methyladenosine Methylation of SNAIL.

Kang T, Zhang C, Lei H, Luo R, Liu M, Wang S, Zhang X, Duan Q, Xiao S, Zheng Y
The Journal of investigative dermatology 2023 Jun;143(6):977-988.e2

---

Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer.

Wang X, Xu J, Sun Y, Cao S, Zeng H, Jin N, Shou M, Tang S, Chen Y, Huang M
Acta pharmaceutica Sinica. B 2023 Jun;13(6):2601-2612

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Anti-oxidative-initiated cognitive impairment amelioration in Alzheimer's disease model rats through preventive transcutaneous electrical acupoint stimulation.

Weng H, Wang Q, Ye R, Bai Y, Yang H, Xu G, Wang Q
Integrative medicine research 2023 Jun;12(2):100946

---

Piperine ameliorates psoriatic skin inflammation by inhibiting the phosphorylation of STAT3.

Lu H, Gong H, Du J, Gao W, Xu J, Cai X, Yang Y, Xiao H
International immunopharmacology 2023 Jun;119:110221

---

Inflachromene inhibits intimal hyperplasia through the HMGB1/2- regulated TLR4-NF-κB pathway.

Teng S, Zhu Z, Wu C, He Y, Zhou S
International immunopharmacology 2023 Jun;119:110198

---

Escherichia coli enhances Th17/Treg imbalance via TLR4/NF-κB signaling pathway in oral lichen planus.

Wang J, Yang J, Xia W, Zhang M, Tang H, Wang K, Zhou C, Qian L, Fan Y
International immunopharmacology 2023 Jun;119:110175

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Characterizing the specific mechanism of series processed Coptidis Rhizoma by multi-organ metabolomics combined with network pharmacology and molecular docking.

Zhou N, Wang Y, Zhang Z, Feng W, Liu T, Cao Y, Zhang J, Zhang B, Zheng X, Li K
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154804

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Effect of STK3 on proliferation and apoptosis of pancreatic cancer cells via PI3K/AKT/mTOR pathway.

Chen J, Liu F, Wu J, Yang Y, He J, Wu F, Yang K, Li J, Jiang Z, Jiang Z
Cellular signalling 2023 Jun;106:110642

---

Elevated expression of myosin VI contributes to breast cancer progression via MAPK/ERK signaling pathway.

Zhan XJ, Wang R, Kuang XR, Zhou JY, Hu XL
Cellular signalling 2023 Jun;106:110633

---

Wnt3a-Loaded Extracellular Vesicles Promote Alveolar Epithelial Regeneration after Lung Injury.

Gao L, Sun Y, Zhang X, Ma D, Xie A, Wang E, Cheng L, Liu S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(18):e2206606

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Discovery of a New-Generation S-Adenosylmethionine-Noncompetitive Covalent Inhibitor Targeting the Lysine Methyltransferase Enhancer of Zeste Homologue 2.

Zhang Y, Yang H, Li B, Li J, Li H, Shi Q, Li B, Wang Z, Zheng J, Zhang Y, Dong H, Huang X, Wang Y
Journal of medicinal chemistry 2023 Jun 8;66(11):7629-7644

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Silencing mouse circular RNA circSlc8a1 by circular antisense cA-circSlc8a1 induces cardiac hepatopathy.

Wu N, Li F, Yang W, Du WW, Awan FM, Zhang C, Lyu J, Misir S, Zeng K, Eshaghi E, Yang BB
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Jun 7;31(6):1688-1704

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A copper complex that combats triple negative breast cancer by restraining angiogenesis.

Zheng H, Hu C, Quan Y, Ye X, Shi X, Guo Z, Wang X
Dalton transactions (Cambridge, England : 2003) 2023 Jun 6;52(22):7626-7634

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Taurochenodeoxycholic acid inhibits intestinal epithelial cell proliferation and induces apoptosis independent of the farnesoid X receptor.

Liu Y, Niu K, Wang R, Liang X, Lin C, Wu X, Zhai Z
Food & function 2023 Jun 6;14(11):5277-5289

---

Discovery of bipyridine amide derivatives targeting pRXRα-PLK1 interaction for anticancer therapy.

Chen J, Zhao T, He F, Zhong Y, Wang S, Tang Z, Qiu Y, Wu Z, Fang M
European journal of medicinal chemistry 2023 Jun 5;254:115341

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Preparation of nanocomposite membranes loaded with taxifolin liposome and its mechanism of wound healing in diabetic mice.

Ding Q, Ding C, Liu X, Zheng Y, Zhao Y, Zhang S, Sun S, Peng Z, Liu W
International journal of biological macromolecules 2023 Jun 30;241:124537

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Role of ionizing radiation activated NRF2 in lung cancer radioresistance.

Xu Q, Zhang P, Han X, Ren H, Yu W, Hao W, Luo B, Khan MI, Chen N
International journal of biological macromolecules 2023 Jun 30;241:124476

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MAGOH is correlated with poor prognosis and is essential for cell proliferation in lower-grade glioma.

Xiao F, Long Z, Guo Y, Zhu H, Zhang Z, Xiao Y, Hu G, Yang Q, Huang K, Guo H
Aging 2023 Jun 30;15(12):5713-5733

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AAV9-Tspyl2 gene therapy retards bleomycin-induced pulmonary fibrosis by modulating downstream TGF-β signaling in mice.

Zhang S, Tong X, Liu S, Huang J, Zhang L, Zhang T, Wang D, Fan H
Cell death & disease 2023 Jun 30;14(6):389

---

DnaJC7 specifically regulates tau seeding.

Perez VA, Sanders DW, Mendoza-Oliva A, Stopschinski BE, Mullapudi V, White CL, Joachimiak LA, Diamond MI
eLife 2023 Jun 30;12

---

APOBEC3B coordinates R-loop to promote replication stress and sensitize cancer cells to ATR/Chk1 inhibitors.

Zong C, Zhang Z, Gao L, He J, Wang Y, Li Q, Liu X, Yang J, Chen D, Huang R, Zheng G, Jin X, Wei W, Jia R, Shen J
Cell death & disease 2023 Jun 3;14(6):348

---

CircHIPK3 negatively regulates autophagy by blocking VCP binding to the Beclin 1 complex in bladder cancer.

Wang C, Liu T, Wang J, Cheng C, Zhang Z, Zhang J, Huang H, Li Y
Discover oncology 2023 Jun 3;14(1):86

---

Palmitoylation at Residue C221 of Japanese Encephalitis Virus NS2A Protein Contributes to Viral Replication Efficiency and Virulence.

Ma X, Xia Q, Liu K, Wu Z, Li C, Xiao C, Dong N, Hameed M, Anwar MN, Li Z, Shao D, Li B, Qiu Y, Wei J, Ma Z
Journal of virology 2023 Jun 29;97(6):e0038223

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Circulating LPS from gut microbiota leverages stenosis-induced deep vein thrombosis in mice.

Liu C, Zhou Y, Gao H, Zhang Z, Zhou Y, Xu Z, Zhang C, Xu Z, Zheng H, Ma YQ
Thrombosis journal 2023 Jun 29;21(1):71

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A core NRF2 gene set defined through comprehensive transcriptomic analysis predicts selective drug resistance and poor multi-cancer prognosis.

Luo G, Kumar H, Alridge K, Rieger S, Jiang E, Chan ER, Soliman A, Mahdi H, Letterio JJ
bioRxiv : the preprint server for biology 2023 Jun 29;

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Down-regulation of the Smad signaling by circZBTB46 via the Smad2-PDLIM5 axis to inhibit type I collagen expression.

Yu J, Yan WZ, Zhang XH, Zheng B, Pan WS, Yang Z, Zhang H, Nie ZY, Ma Y, Bai Y, Zhang L, Feng DD, Wen JK
Journal of geriatric cardiology : JGC 2023 Jun 28;20(6):431-447

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GATA zinc finger protein p66β promotes breast cancer cell migration by acting as a co-activator of Snail.

Zou X, Ma L, Zhang Y, Zhang Q, Xu C, Zhang D, Chu Y, Zhang J, Li M, Zhang H, Wang J, Peng C, Wei G, Wu Y, Hou Z, Jia H
Cell death & disease 2023 Jun 28;14(6):382

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Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration.

Sun L, Zhang X, Wu S, Liu Y, Guerrero-Juarez CF, Liu W, Huang J, Yao Q, Yin M, Li J, Ramos R, Liao Y, Wu R, Xia T, Zhang X, Yang Y, Li F, Heng S, Zhang W, Yang M, Tzeng CM, Ji C, Plikus MV, Gallo RL, Zhang LJ
Cell reports 2023 Jun 27;42(6):112647

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The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-κB.

Fei X, Huang J, Li F, Wang Y, Shao Z, Dong L, Wu Y, Li B, Zhang X, Lv B, Zhao Y, Weng Q, Chen K, Zhang M, Yang S, Zhang C, Zhang M, Li W, Ying S, Sun Q, Chen Z, Shen H
Cell reports 2023 Jun 27;42(6):112586

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The Benefits of Nanosized Magnesium Oxide in Fish Megalobrama amblycephala: Evidence in Growth Performance, Redox Defense, Glucose Metabolism, and Magnesium Homeostasis.

Zhang L, Liu Z, Deng Y, He C, Liu W, Li X
Antioxidants (Basel, Switzerland) 2023 Jun 27;12(7)

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Notch mediates the glycolytic switch via PI3K/Akt signaling to support embryonic development.

Wang H, Liang W, Wang X, Zhan Y, Wang W, Yang L, Zhu Y
Cellular & molecular biology letters 2023 Jun 26;28(1):50

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The Clock-modulatory Activity of Nobiletin Suppresses Adipogenesis Via Wnt Signaling.

Xiong X, Kiperman T, Li W, Dhawan S, Lee J, Yechoor V, Ma K
Endocrinology 2023 Jun 26;164(8)

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SIAH1/CTR9 axis promotes the epithelial-mesenchymal transition of hepatocellular carcinoma.

Liu Z, Luo P, Cao K, Hu Q, Hu B, Cui L, Wang X, Shi H, Zhang B, Wang R
Carcinogenesis 2023 Jun 24;44(4):304-316

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Perturbation of endoplasmic reticulum proteostasis triggers tissue injury in the thyroid gland.

Zhang X, Young C, Liao XH, Refetoff S, Torres M, Tomer Y, Stefan-Lifshitz M, Zhang H, Larkin D, Fang D, Qi L, Arvan P
JCI insight 2023 Jun 22;8(12)

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Ginsenoside Rk3 Regulates Nonalcoholic Steatohepatitis by Modulation of Intestinal Flora and the PI3K/AKT Signaling Pathway in C57BL/6 Mice.

Guo M, Zhu C, Fu R, Ma X, Duan Z, Fan D
Journal of agricultural and food chemistry 2023 Jun 21;71(24):9370-9380

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C-X-C Motif Chemokine 3 Promotes the Inflammatory Response of Microglia after Escherichia coli-Induced Meningitis.

Qu X, Dou B, Yang R, Tan C, Chen H, Wang X
International journal of molecular sciences 2023 Jun 21;24(13)

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METTL16 promotes glycolytic metabolism reprogramming and colorectal cancer progression.

Wei W, Zhang ZY, Shi B, Cai Y, Zhang HS, Sun CL, Fei YF, Zhong W, Zhang S, Wang C, He B, Jiang GM, Wang H
Journal of experimental & clinical cancer research : CR 2023 Jun 20;42(1):151

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Profiling the metabolome of uterine fluid for early detection of ovarian cancer.

Wang P, Ma J, Li W, Wang Q, Xiao Y, Jiang Y, Gu X, Wu Y, Dong S, Guo H, Li M
Cell reports. Medicine 2023 Jun 20;4(6):101061

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ULK1-mediated metabolic reprogramming regulates Vps34 lipid kinase activity by its lactylation.

Jia M, Yue X, Sun W, Zhou Q, Chang C, Gong W, Feng J, Li X, Zhan R, Mo K, Zhang L, Qian Y, Sun Y, Wang A, Zou Y, Chen W, Li Y, Huang L, Yang Y, Zhao Y, Cheng X
Science advances 2023 Jun 2;9(22):eadg4993

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Chemo- and Diastereoselective Cycloisomerization/[2 + 3] Cycloaddition of Enynamides: Synthesis of Spiropyrazolines as Potential Anticancer Reagents.

Fang H, Li Y, Zhang L, Yan ZH, Ma K, Peng C, Huang W, Zhan G
The Journal of organic chemistry 2023 Jun 2;88(11):7311-7319

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Effects of Si-Miao-Yong-An decoction on myocardial I/R rats by regulating gut microbiota to inhibit LPS-induced TLR4/NF-κB signaling pathway.

Cui Y, Zhang F, Xu W, Li Z, Zou J, Gao P, Hu J
BMC complementary medicine and therapies 2023 Jun 2;23(1):180

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Oridonin promotes endoplasmic reticulum stress via TP53-repressed TCF4 transactivation in colorectal cancer.

Zhou F, Gao H, Shang L, Li J, Zhang M, Wang S, Li R, Ye L, Yang S
Journal of experimental & clinical cancer research : CR 2023 Jun 19;42(1):150

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Biallelic variants in MAD2L1BP (p31(comet)) cause female infertility characterized by oocyte maturation arrest.

Huang L, Li W, Dai X, Zhao S, Xu B, Wang F, Jin RT, Luo L, Wu L, Jiang X, Cheng Y, Zou J, Xu C, Tong X, Fan HY, Zhao H, Bao J
eLife 2023 Jun 19;12

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Genetic lineage tracing reveals stellate cells as contributors to myofibroblasts in pancreas and islet fibrosis.

Wang J, Li T, Zhou Y, Wang X, Carvalho V, Ni C, Li W, Wang Q, Chen Y, Shang Z, Qiu S, Sun Z
iScience 2023 Jun 16;26(6):106988

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Zhx2 maintains islet β-cell mass and function by transcriptionally regulating Pax6.

Ding L, Zhang Y, Wang Y, Wang Y, Tong Z, Li P, Chen C, Wang B, Yue X, Li C, Wu Z, Liang X, Ma C, Gao L
iScience 2023 Jun 16;26(6):106871

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Cathepsin K promotes the proliferation of hepatocellular carcinoma cells through induction of SIAH1 ubiquitination and degradation.

Zhang C, Liu Z, Wang X, Zhang B, Cui L, Hu Q, Hu B, Cao K, Shan W, Shi H, Wang R
iScience 2023 Jun 16;26(6):106852

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Aminosalicylates target GPR35, partly contributing to the prevention of DSS-induced colitis.

Otkur W, Wang J, Hou T, Liu F, Yang R, Li Y, Xiang K, Pei S, Qi H, Lin H, Zhou H, Zhang X, Piao HL, Liang X
European journal of pharmacology 2023 Jun 15;949:175719

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ZDHHC2-Mediated AGK Palmitoylation Activates AKT-mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma.

Sun Y, Zhu L, Liu P, Zhang H, Guo F, Jin X
Cancer research 2023 Jun 15;83(12):2034-2051

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Subconjunctival Administration of Mesenchymal Stem Cells Alleviates Ocular Inflammation in a Murine Model of Corneal Alkali Burn.

Chen M, Chen X, Li X, Wang J, Wu J, Wang Q, Huang Y, Li Z, Wang L
Stem cells (Dayton, Ohio) 2023 Jun 15;41(6):592-602

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Microglia activation mediates circadian rhythm disruption-induced cognitive impairment in mice.

Meng D, Yang M, Zhang H, Zhang L, Song H, Liu Y, Zeng Y, Yang B, Wang X, Chen Y, Liu R
Journal of neuroimmunology 2023 Jun 15;379:578102

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Combination effects of amino acid transporter LAT1 inhibitor nanvuranlat and cytotoxic anticancer drug gemcitabine on pancreatic and biliary tract cancer cells.

Nishikubo K, Ohgaki R, Liu X, Okanishi H, Xu M, Endou H, Kanai Y
Cancer cell international 2023 Jun 15;23(1):116

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Baicalein Suppresses NLRP3 and AIM2 Inflammasome-Mediated Pyroptosis in Macrophages Infected by Mycobacterium tuberculosis via Induced Autophagy.

Ning B, Shen J, Liu F, Zhang H, Jiang X
Microbiology spectrum 2023 Jun 15;11(3):e0471122

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Rapamycin Inhibits Osteoclastogenesis and Prevents LPS-Induced Alveolar Bone Loss by Oxidative Stress Suppression.

Feng C, Liu Y, Zhang BY, Zhang H, Shan FY, Li TQ, Zhao ZN, Wang XX, Zhang XY
ACS omega 2023 Jun 13;8(23):20739-20754

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Bioengineered Bacteriophage-Like Nanoparticles as RNAi Therapeutics to Enhance Radiotherapy against Glioblastomas.

Pang HH, Huang CY, Chen PY, Li NS, Hsu YP, Wu JK, Fan HF, Wei KC, Yang HW
ACS nano 2023 Jun 13;17(11):10407-10422

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Gastroprotective Effects of the Aqueous Extract of Finger Citron Pickled Products against Ethanol-Induced Gastric Damage: In Vitro and In Vivo Studies.

Chen X, Yang D, Wang Q, Zhou A
Foods (Basel, Switzerland) 2023 Jun 13;12(12)

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Yi-Shen-Xie-Zhuo formula alleviates cisplatin-induced AKI by regulating inflammation and apoptosis via the cGAS/STING pathway.

Qi J, Luo Q, Zhang Q, Wu M, Zhang L, Qin L, Xue Q, Nie X
Journal of ethnopharmacology 2023 Jun 12;309:116327

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Antidepressive mechanisms of rhynchophylline in mice with chronic unpredictable stress-induced depression.

Liu EY, Yang CL, Tsai JC, Cheng HY, Peng WH
Journal of ethnopharmacology 2023 Jun 12;309:116302

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Ubiquitination of GRK2 Is Required for the β-Arrestin-Biased Signaling Pathway of Dopamine D2 Receptors to Activate ERK Kinases.

Liu H, Ma H, Zeng X, Wu C, Acharya S, Sudan SK, Zhang X
International journal of molecular sciences 2023 Jun 12;24(12)

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The synbiotic mixture of lactulose and Bacillus coagulans protects intestinal barrier dysfunction and apoptosis in weaned piglets challenged with lipopolysaccharide.

Zheng W, Zhao Z, Yang Y, Ding L, Yao W
Journal of animal science and biotechnology 2023 Jun 11;14(1):80

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EFFECT OF EXOSOMES DERIVED FROM BONE MARROW MESENCHYMAL STEM CELLS ON PROGRAMMED CELL DEATH IN BLAST-INDUCED LUNG INJURY IN RATS.

Deng M, He J, Hao C, Guo Y, Si H, Deng X, Zhang C, Li S, Yao S, Ren W, Yao W
Shock (Augusta, Ga.) 2023 Jun 1;59(6):955-965

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MiR-24-3p/Dio3 axis is essential for BDE47 to induce local thyroid hormone disorder and neurotoxicity.

Liu M, Yu Z, Zhao Z, Yang F, Zhou M, Wang C, Tian X, Zhang B, Liang G, Liu X, Shao J
Toxicology 2023 Jun 1;491:153527

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Dexamethasone enhances venetoclax-induced apoptosis in acute myeloid leukemia cells.

Wang H, Zhou J, Ma X, Jiao C, Chen E, Wu Z, Zhang Y, Pan M, Cui J, Luan C, Ge J
Medical oncology (Northwood, London, England) 2023 Jun 1;40(7):193

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CM3-SII polysaccharide obtained from Cordyceps militaris ameliorates hyperlipidemia in heterozygous LDLR-deficient hamsters by modulating gut microbiota and NPC1L1 and PPARα levels.

Yu WQ, Wang XL, Ji HH, Miao M, Zhang BH, Li H, Zhang ZY, Ji CF, Guo SD
International journal of biological macromolecules 2023 Jun 1;239:124293

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An O-GlcNAc transferase pathogenic variant linked to intellectual disability affects pluripotent stem cell self-renewal.

Omelková M, Fenger CD, Murray M, Hammer TB, Pravata VM, Bartual SG, Czajewski I, Bayat A, Ferenbach AT, Stavridis MP, van Aalten DMF
Disease models & mechanisms 2023 Jun 1;16(6)

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Tissue-resident CXCR4(+) macrophage as a poor prognosis signature promotes pancreatic ductal adenocarcinoma progression.

Liao Z, Ye L, Li T, Jin X, Lin X, Fei Q, Zhang H, Shi S, Yu X, Jin K, Wu W
International journal of cancer 2023 Jun 1;152(11):2396-2409

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Lymphocyte-Related Immunomodulatory Therapy with Siponimod (BAF-312) Improves Outcomes in Mice with Acute Intracerebral Hemorrhage.

Zhang Z, Li Y, Shi J, Zhu L, Dai Y, Fu P, Liu S, Hong M, Zhang J, Wang J, Jiang C
Aging and disease 2023 Jun 1;14(3):966-991

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Curcumin preconditioning enhances the neuroprotective effects of olfactory mucosa-derived mesenchymal stem cells on experimental intracerebral hemorrhage.

Huang Y, Liu J, He J, Tan F, Lu M, Yuan F, Zhu X, Kong L
Heliyon 2023 Jul;9(7):e17874

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Peripheral immune cell death in sepsis based on bulk RNA and single-cell RNA sequencing.

Liu S, Duan C, Xie J, Zhang J, Luo X, Wang Q, Liang X, Zhao X, Zhuang R, Zhao W, Yin W
Heliyon 2023 Jul;9(7):e17764

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The role of TRPV4 in the regulation of retinal ganglion cells apoptosis in rat and mouse.

Wang Y, Zhang W, Xu G, Shi C, Wang X, Qu J, Wang H, Liu C
Heliyon 2023 Jul;9(7):e17583

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Natural Oncolysis of Enterovirus 71 in Antitumor Therapy of Colorectal Cancer.

Ruan Z, Chi J, Kong Y, Li C, Ruan X, Zhou X, Chen Y, Li Y, Luo Z
Advanced biology 2023 Jul;7(7):e2200336

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Targeting ACYP1-mediated glycolysis reverses lenvatinib resistance and restricts hepatocellular carcinoma progression.

Wang S, Zhou L, Ji N, Sun C, Sun L, Sun J, Du Y, Zhang N, Li Y, Liu W, Lu W
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2023 Jul;69:100976

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Intermittent Fasting Alleviates Non-Alcoholic Steatohepatitis by Regulating Bile Acid Metabolism and Promoting Fecal Bile Acid Excretion in High-Fat and High-Cholesterol Diet Fed Mice.

Lin X, Zhu X, Xin Y, Zhang P, Xiao Y, He T, Guo H
Molecular nutrition & food research 2023 Jul;67(14):e2200595

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Advanced glycation end products promote the progression of chronic kidney diseases by targeting calpain 6.

Zhang Y, Han H, Qian Y, Wang Q, Jiang M
Amino acids 2023 Jul;55(7):903-912

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MLL4 Regulates the Progression of Non-Small-Cell Lung Cancer by Regulating the PI3K/AKT/SOX2 Axis.

Yang Y, Qiu R, Weng Q, Xu Z, Song J, Zhao S, Meng M, Zhang D, Kong C, Wang H, Xu M, Zhao Z, Ji J
Cancer research and treatment 2023 Jul;55(3):778-803

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RNA-binding Protein QKI Inhibits Osteogenic Differentiation Via Suppressing Wnt Pathway.

Yan Z, Ruan B, Wang S, Du T, Shao X, Chen G, Wang L, Zhai D, Zhu S, Lu Z, Cao X
Archives of medical research 2023 Jul;54(5):102853

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Sevoflurane-induced P300 promotes neuron apoptosis via Sp1/CDK9 pathway.

Zhou X, Liu C, Xia D
Clinical and experimental pharmacology & physiology 2023 Jul;50(7):541-553

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mGluR5 in hippocampal CA1 pyramidal neurons mediates stress-induced anxiety-like behavior.

Li X, Du ZJ, Xu JN, Liang ZM, Lin S, Chen H, Li SJ, Li XW, Yang JM, Gao TM
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2023 Jul;48(8):1164-1174

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Hypoxia-Preconditioned Bone Marrow Mesenchymal Stem Cells Improved Cerebral Collateral Circulation and Stroke Outcome in Mice.

Tian H, Yang X, Zhao J, Liu X, Liu X, Cai Y, Wehbe A, Ding Y, Yu S, Wei L, Liu L
Arteriosclerosis, thrombosis, and vascular biology 2023 Jul;43(7):1281-1294

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The choleretic role of tauroursodeoxycholic acid exacerbates alpha-naphthylisothiocyanate induced cholestatic liver injury through the FXR/BSEP pathway.

Zhao J, Song G, Weng F, Li Y, Zou B, Jin J, Yan D, Sun X, Liu C, Qiu FR
Journal of applied toxicology : JAT 2023 Jul;43(7):1095-1103

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USP13 deubiquitinates and stabilizes cyclin D1 to promote gastric cancer cell cycle progression and cell proliferation.

Ma C, Wang D, Tian Z, Gao W, Zang Y, Qian L, Xu X, Jia J, Liu Z
Oncogene 2023 Jul;42(29):2249-2262

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miR-101-5p suppresses trophoblast cell migration and invasion via modulating the DUSP6-ERK1/2 axis in preeclampsia.

Xu J, Wang J, Chen M, Chao B, He J, Bai Y, Luo X, Liu H, Xie L, Tao Y, Qi H, Luo X
Journal of assisted reproduction and genetics 2023 Jul;40(7):1597-1610

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Effect of peroxiredoxin 1 on the regulation of trophoblast function by affecting autophagy and oxidative stress in preeclampsia.

Zhou M, Guo J, Li S, Li A, Fang Z, Zhao M, Zhang M, Wang X
Journal of assisted reproduction and genetics 2023 Jul;40(7):1573-1587

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SLC25A22 as a Key Mitochondrial Transporter Against Ferroptosis by Producing Glutathione and Monounsaturated Fatty Acids.

Liu Y, Wang Y, Lin Z, Kang R, Tang D, Liu J
Antioxidants & redox signaling 2023 Jul;39(1-3):166-185

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HDAC inhibitor chidamide overcomes drug resistance in chronic myeloid leukemia with the T315i mutation through the Akt-autophagy pathway.

Yin L, Zhang Q, Xie S, Cheng Z, Li R, Zhu H, Yu Q, Yuan H, Wang C, Peng H, Zhang G
Human cell 2023 Jul;36(4):1564-1577

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Cathepsin B S-nitrosylation promotes ADAR1-mediated editing of its own mRNA transcript via an ADD1/MATR3 regulatory axis.

Lin Z, Zhao S, Li X, Miao Z, Cao J, Chen Y, Shi Z, Zhang J, Wang D, Chen S, Wang L, Gu A, Chen F, Yang T, Sun K, Han Y, Xie L, Chen H, Ji Y
Cell research 2023 Jul;33(7):546-561

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Absorbable suture knots on the supraspinatus tendon prevent adverse effects of nonabsorbable suture knots in a rat model.

Ben H, Luo C, Cheng J, Zeng CH, Zhou Y, Jeon IH, Sun Y
Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA 2023 Jul;31(7):2572-2580

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The deubiquitylating enzyme USP35 restricts regulated cell death to promote survival of renal clear cell carcinoma.

Wang S, Wang T, Zhang X, Cheng S, Chen C, Yang G, Wang F, Wang R, Zhang Q, Yang D, Zhang Y, Liu S, Qin H, Liu Q, Liu H
Cell death and differentiation 2023 Jul;30(7):1757-1770

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The deubiquitinase USP28 maintains the expression of the transcription factor MYCN and is essential in neuroblastoma cells.

Li J, Peng J, Wu L, Shen X, Zhen X, Zhang Y, Ma H, Xu Y, Xiong Q, Zhu Q, Zhang P
The Journal of biological chemistry 2023 Jul;299(7):104856

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Nutrient-dependent regulation of β-cell proinsulin content.

Xu X, Arunagiri A, Alam M, Haataja L, Evans CR, Zhao I, Castro-Gutierrez R, Russ HA, Demangel C, Qi L, Tsai B, Liu M, Arvan P
The Journal of biological chemistry 2023 Jul;299(7):104836

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Palmitic acid-induced ferroptosis via CD36 activates ER stress to break calcium-iron balance in colon cancer cells.

Kuang H, Sun X, Liu Y, Tang M, Wei Y, Shi Y, Li R, Xiao G, Kang J, Wang F, Peng J, Xu H, Zhou F
The FEBS journal 2023 Jul;290(14):3664-3687

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Radiation resistance of cancer cells caused by mitochondrial dysfunction depends on SIRT3-mediated mitophagy.

Wei Y, Xiao G, Xu H, Sun X, Shi Y, Wang F, Kang J, Peng J, Zhou F
The FEBS journal 2023 Jul;290(14):3629-3645

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Pemetrexed induces ROS generation and cellular senescence by attenuating TS-mediated thymidylate metabolism to reverse gefitinib resistance in NSCLC.

Chen Y, Zhang C, Jin S, Li J, Dai J, Zhang Z, Guo R
Journal of cellular and molecular medicine 2023 Jul;27(14):2032-2044

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RBM25 induces trophoblast epithelial-mesenchymal transition and preeclampsia disorder by enhancing the positive feedback loop between Grhl2 and RBM25.

Zhang J, Chen WQ, Yang K, Wang ZX, Sun DL, Peng YY, Yu M, Wang SX, Guo Q
Experimental biology and medicine (Maywood, N.J.) 2023 Jul;248(14):1267-1277

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Sacubitril/Valsartan Ameliorates Crizotinib-Induced Cardiotoxicity in Mice.

Cheng L, Duan J, Tse G, Liu T, Li G
Reviews in cardiovascular medicine 2023 Jul;24(7):192

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Neotuberostemonine and tuberostemonine ameliorate pulmonary fibrosis through suppressing TGF-β and SDF-1 secreted by macrophages and fibroblasts via the PI3K-dependent AKT and ERK pathways.

Fu S, Song X, Hu Y, Zhu Q, Lv X, Tang X, Zhang M
Chinese journal of natural medicines 2023 Jul;21(7):527-539

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Eucommia lignans alleviate the progression of diabetic nephropathy through mediating the AR/Nrf2/HO-1/AMPK axis in vivo and in vitro.

Huang Q, Zhang Y, Jiang Y, Huang L, Liu Q, Ouyang D
Chinese journal of natural medicines 2023 Jul;21(7):516-526

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Membrane-dependent actin polymerization mediated by the Legionella pneumophila effector protein MavH.

Zhang Q, Wan M, Kudryashova E, Kudryashov DS, Mao Y
PLoS pathogens 2023 Jul;19(7):e1011512

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Bile duct ligation increased dopamine levels in the cerebral cortex of rats partly due to induction of tyrosine hydroxylase.

Kong W, Sun X, Yu S, Liu P, Zheng X, Zhang J, Zhu L, Jiang T, Jin M, Gao J, Fan X, Liu X, Liu L
British journal of pharmacology 2023 Jul;180(13):1690-1709

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Emodin attenuates inflammation and demyelination in experimental autoimmune encephalomyelitis.

Cui YR, Bu ZQ, Yu HY, Yan LL, Feng J
Neural regeneration research 2023 Jul;18(7):1535-1541

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Betulinic acid mitigates zearalenone-induced liver injury by ERS/MAPK/Nrf2 signaling pathways in mice.

Wu J, Li J, Wu Y, Yang M, Chen Y, Wang N, Wang J, Yuan Z, Yi J, Yang C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113811

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ACC010, a novel BRD4 inhibitor, synergized with homoharringtonine in acute myeloid leukemia with FLT3-ITD.

Qian Y, Zhang X, Mao S, Wei W, Lin X, Ling Q, Ye W, Li F, Pan J, Zhou Y, Zhao Y, Huang X, Huang J, Tong H, Sun J, Jin J
Molecular oncology 2023 Jul;17(7):1402-1418

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Resveratrol Promotes Gluconeogenesis by Inhibiting SESN2-mTORC2-AKT Pathway in Calf Hepatocytes.

Wang G, Qin S, Geng H, Zheng Y, Li R, Xia C, Chen L, Yao J, Deng L
The Journal of nutrition 2023 Jul;153(7):1930-1943

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Targeting NAD metabolism regulates extracellular adenosine levels to improve the cytotoxicity of CD8+ effector T cells in the tumor microenvironment of gastric cancer.

Liu HY, Wang FH, Liang JM, Xiang YY, Liu SH, Zhang SW, Zhu CM, He YL, Zhang CH
Journal of cancer research and clinical oncology 2023 Jul;149(7):2743-2756

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Alpinia oxyphylla Miq. volatile oil ameliorates depressive behaviors and inhibits neuroinflammation in CUMS-exposed mice by inhibiting the TLR4-medicated MyD88/NF-κB signaling pathway.

Wu B, Gan A, Wang R, Lin F, Yan T, Jia Y
Journal of chemical neuroanatomy 2023 Jul;130:102270

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rTMS treatment for abrogating intracerebral hemorrhage-induced brain parenchymal metabolite clearance dysfunction in male mice by regulating intracranial lymphatic drainage.

Liu Y, Liu X, Sun P, Li J, Nie M, Gong J, He A, Zhao M, Yang C, Wang Z
Brain and behavior 2023 Jul;13(7):e3062

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Suramin ameliorates osteoarthritis by acting on the Nrf2/HO-1 and NF-κB signaling pathways in chondrocytes and promoting M2 polarization in macrophages.

Shen PC, Huang SH, Liu ZM, Lu CC, Chou SH, Tien YC
International immunopharmacology 2023 Jul;120:110295

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Ergolide covalently binds NLRP3 and inhibits NLRP3 inflammasome-mediated pyroptosis.

Ren M, Chen J, Xu H, Li W, Wang T, Chi Z, Lin Y, Zhang A, Chen G, Wang X, Sun X, Liang G, Wang J, Luo W
International immunopharmacology 2023 Jul;120:110292

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Stromal cell-derived small extracellular vesicles enhance radioresistance of prostate cancer cells via interleukin-8-induced autophagy.

Wang X, Xu F, Kou H, Zheng Y, Yang J, Xu Z, Fang Y, Sun W, Zhu S, Jiang Q, Wei X, Xu Y
Journal of extracellular vesicles 2023 Jul;12(7):e12342

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COLEC10 Induces Endoplasmic Reticulum Stress by Occupying GRP78 and Inhibits Hepatocellular Carcinoma.

Cai MN, Chen DM, Xiao LX, Li SS, Liao CH, Li J, Huang ZX, Wang JL, Gu YR, Gu L, Huang YH, Lian YF
Laboratory investigation; a journal of technical methods and pathology 2023 Jul;103(7):100130

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Targeting macrophagic PIM-1 alleviates osteoarthritis by inhibiting NLRP3 inflammasome activation via suppressing mitochondrial ROS/Cl(-) efflux signaling pathway.

Zhang Z, Xie S, Qian J, Gao F, Jin W, Wang L, Yan L, Chen H, Yao W, Li M, Wang X, Zhu L
Journal of translational medicine 2023 Jul 8;21(1):452

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Synergistic Effect of Treatment with Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus and Lipopolysaccharide on the Inflammatory Response of Porcine Pulmonary Microvascular Endothelial Cells.

Yao X, Dai W, Yang S, Wang Z, Zhang Q, Meng Q, Zhang T
Viruses 2023 Jul 8;15(7)

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Abnormal Expression of Prolyl Oligopeptidase (POP) and Its Catalytic Products Ac-SDKP Contributes to the Ovarian Fibrosis Change in Polycystic Ovary Syndrome (PCOS) Mice.

Han S, Wang S, Fan X, Chen M, Wang X, Huang Y, Zhang H, Ma Y, Wang J, Zhang C
Biomedicines 2023 Jul 7;11(7)

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Gasdermin D licenses MHCII induction to maintain food tolerance in small intestine.

He K, Wan T, Wang D, Hu J, Zhou T, Tao W, Wei Z, Lu Q, Zhou R, Tian Z, Flavell RA, Zhu S
Cell 2023 Jul 6;186(14):3033-3048.e20

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Microglial-to-neuronal CCR5 signaling regulates autophagy in neurodegeneration.

Festa BP, Siddiqi FH, Jimenez-Sanchez M, Won H, Rob M, Djajadikerta A, Stamatakou E, Rubinsztein DC
Neuron 2023 Jul 5;111(13):2021-2037.e12

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Alphavirus-induced transcriptional and translational shutoffs play major roles in blocking the formation of stress granules.

Palchevska O, Dominguez F, Frolova EI, Frolov I
bioRxiv : the preprint server for biology 2023 Jul 5;

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SFRP1 Expression is Inversely Associated With Metastasis Formation in Canine Mammary Tumours.

Seitz J, Bilsland A, Puget C, Baasner I, Klopfleisch R, Stein T
Journal of mammary gland biology and neoplasia 2023 Jul 4;28(1):15

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CircRNA-02191 regulating unsaturated fatty acid synthesis by adsorbing miR-145 to enhance CD36 expression in bovine mammary gland.

Chen Z, Wang Y, Wang K, Zhang Z, Han M, Li G, Zhang B, Yang Y, Loor JJ, Yang Z, Zhong F, Dai R, Wang M
International journal of biological macromolecules 2023 Jul 31;244:125306

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Exosomes from tannic acid-stimulated macrophages accelerate wound healing through miR-221-3p mediated fibroblasts migration by targeting CDKN1b.

Song X, Chen Y, Chen X, Zhao X, Zou Y, Li L, Zhou X, Li M, Zhang D, Ye G, Jia R, Yin Z
International journal of biological macromolecules 2023 Jul 31;244:125088

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Long non-coding RNA PVT1 regulates atherosclerosis progression via the microRNA-106b-5p/ACSL4 axis.

Zhang M, Yu Z, Zhao L, Luo H
Biochemical and biophysical research communications 2023 Jul 30;667:170-179

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FBXL4 ubiquitin ligase deficiency promotes mitophagy by elevating NIX levels.

Elcocks H, Brazel AJ, McCarron KR, Kaulich M, Husnjak K, Mortiboys H, Clague MJ, Urbé S
The EMBO journal 2023 Jul 3;42(13):e112799

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circACTA2 inhibits NLRP3 inflammasome-mediated inflammation via interacting with NF-κB in vascular smooth muscle cells.

Bai Y, Zhang L, Zheng B, Zhang X, Zhang H, Zhao A, Yu J, Yang Z, Wen J
Cellular and molecular life sciences : CMLS 2023 Jul 27;80(8):229

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Single-cell transcriptomics reveals intestinal cell heterogeneity and identifies Ep300 as a potential therapeutic target in mice with acute liver failure.

Yin J, Zhao Z, Huang J, Xiao Y, Rehmutulla M, Zhang B, Zhang Z, Xiang M, Tong Q, Zhang Y
Cell discovery 2023 Jul 25;9(1):77

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αKG-driven RNA polymerase II transcription of cyclin D1 licenses malic enzyme 2 to promote cell-cycle progression.

Yang Y, Zhang Z, Li W, Si Y, Li L, Du W
Cell reports 2023 Jul 25;42(7):112770

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Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2.

Wu Z, Cao Z, Yao H, Yan X, Xu W, Zhang M, Jiao Z, Zhang Z, Chen J, Liu Y, Zhang M, Wang D
Cell reports 2023 Jul 25;42(7):112693

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Astrocytic α4-containing nAChR signaling in the hippocampus governs the formation of temporal association memory.

Ma W, Si T, Wang Z, Wen P, Zhu Z, Liu Q, Wang J, Xu F, Li Q
Cell reports 2023 Jul 25;42(7):112674

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SIRT3 ameliorates diabetes-associated cognitive dysfunction via regulating mitochondria-associated ER membranes.

Chang Y, Wang C, Zhu J, Zheng S, Sun S, Wu Y, Jiang X, Li L, Ma R, Li G
Journal of translational medicine 2023 Jul 22;21(1):494

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Iron induces B cell pyroptosis through Tom20-Bax-caspase-gasdermin E signaling to promote inflammation post-spinal cord injury.

Wu C, Wang L, Chen S, Shi L, Liu M, Tu P, Sun J, Zhao R, Zhang Y, Wang J, Pan Y, Ma Y, Guo Y
Journal of neuroinflammation 2023 Jul 22;20(1):171

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LILRB2/PirB mediates macrophage recruitment in fibrogenesis of nonalcoholic steatohepatitis.

Li DP, Huang L, Kan RR, Meng XY, Wang SY, Zou HJ, Guo YM, Luo PQ, Pan LM, Xiang YX, Mao BB, Xie YY, Wang ZH, Yang M, He R, Yang Y, Liu ZL, Xie JH, Ma DL, Zhang BP, Shao SY, Chen X, Xu SM, He WT, Li WJ, Chen Y, Yu XF
Nature communications 2023 Jul 22;14(1):4436

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Dephosphorylation of Six2Y129 protects tyrosine hydroxylase-positive cells in SNpc by regulating TEA domain 1 expression.

Zhang CT, Qin DL, Cao XY, Kan JS, Huang XX, Gao DS, Gao J
iScience 2023 Jul 21;26(7):107049

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ZIC2 induces pro-tumor macrophage polarization in nasopharyngeal carcinoma by activating the JUNB/MCSF axis.

Liu Q, Yang T, Zhang Y, Hu ZD, Liu YM, Luo YL, Liu SX, Zhang H, Zhong Q
Cell death & disease 2023 Jul 21;14(7):455

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Novel Protein C6ORF120 Promotes Apoptosis through Mitochondria-dependent Pathway in CD4 (+)T Lymphocytes.

Liu H, Wang X, Wang P, Wang YQ, Yi YY, Li X
Biomedical and environmental sciences : BES 2023 Jul 20;36(7):639-643

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HnRNP A1 Suppresses the Odontogenic Differentiation and the Inclusion of RUNX2 Exon 5 of Dental Mesenchymal Cells.

Zhang Y, Huang J, Yan L, Jia R, Guo J
Frontiers in bioscience (Landmark edition) 2023 Jul 19;28(7):139

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Combined surface functionalization of MSC membrane and PDA inhibits neurotoxicity induced by Fe(3)O(4) in mice based on apoptosis and autophagy through the ASK1/JNK signaling pathway.

Li Y, Liu T, Li X, Yang M, Liu T, Bao J, Jiang M, Hu L, Wang Y, Shao P, Jiang J
Aging 2023 Jul 19;15(14):6933-6949

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Transcriptional analysis of the expression and prognostic value of lipid droplet-localized proteins in hepatocellular carcinoma.

Zhang Y, Liang X, Lian Q, Liu L, Zhang B, Dong Z, Liu K
BMC cancer 2023 Jul 18;23(1):677

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Structures of p53/BCL-2 complex suggest a mechanism for p53 to antagonize BCL-2 activity.

Wei H, Wang H, Wang G, Qu L, Jiang L, Dai S, Chen X, Zhang Y, Chen Z, Li Y, Guo M, Chen Y
Nature communications 2023 Jul 18;14(1):4300

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Selective activation of AKAP150/TRPV1 in ventrolateral periaqueductal gray GABAergic neurons facilitates conditioned place aversion in male mice.

Bai X, Zhang K, Ou C, Nie B, Zhang J, Huang Y, Zhang Y, Huang J, Ouyang H, Cao M, Huang W
Communications biology 2023 Jul 17;6(1):742

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COPS3 inhibition promotes cell proliferation blockage and anoikis via regulating PFKFB3 in osteosarcoma cancer cells.

Zhang F, Li Q, Zhang Y, Li N, Rao M, Li S, Ai Z, Yan S, Tian Z
European journal of pharmacology 2023 Jul 15;951:175799

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Proteomic analysis reveals the mechanisms of the astaxanthin suppressed foam cell formation.

Liu A, Li R, Zaaboul F, He M, Li X, Shi J, Liu Y, Xu YJ
Life sciences 2023 Jul 15;325:121774

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An animal model induced by bilateral cavernous nerve crushing mimics post-radical prostatectomy erectile dysfunction in old rats.

Ge Y, Hu D, Xi Y, Wang H, Xia T, Chen J, Pu X, Xiao H
Life sciences 2023 Jul 15;325:121767

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Resveratrol plays an anti-fibrotic and anti-autophagy role by stimulating miR-192-5p expression in urethral fibrosis.

Lv J, Zhang R, Li D, Liu Y
Functional & integrative genomics 2023 Jul 14;23(3):241

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N-Acetylaspartate Drives Oligodendroglial Differentiation via Histone Deacetylase Activation.

Dominicis A, Del Giovane A, Torreggiani M, Recchia AD, Ciccarone F, Ciriolo MR, Ragnini-Wilson A
Cells 2023 Jul 14;12(14)

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JMJD8 regulates neuropathic pain by affecting spinal cord astrocyte differentiation.

Li Y, Zhang Y, Zhou Z, Yi L, Ji F, Zhang K, Zhang Y, Xu H
Neuroscience letters 2023 Jul 13;809:137307

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Identification of residues critical for the extension of Munc18-1 domain 3a.

Wang X, Gong J, Zhu L, Chen H, Jin Z, Mo X, Wang S, Yang X, Ma C
BMC biology 2023 Jul 13;21(1):158

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Fetal factors disrupt placental and maternal iron homeostasis in murine β-thalassemia.

Yu Y, Woloshun RR, Lee JK, Ebea PO, Zhu S, Nemeth E, Garrick LM, Garrick MD, Collins JF
Blood 2023 Jul 13;142(2):185-196

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Activation of the IKK2-NFκB pathway in VSMCs inhibits calcified vascular stiffness in CKD by reducing the secretion of calcifying extracellular vesicles.

Miyazaki-Anzai S, Masuda M, Keenan AL, Shiozaki Y, Miyazaki M
bioRxiv : the preprint server for biology 2023 Jul 12;

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CXCR4-Targeted Necrosis-Inducing Peptidomimetic for Treating Breast Cancer.

Akonnor A, Makise M, Kuniyasu A
ACS omega 2023 Jul 11;8(27):24467-24476

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Embryonic Exposure to UV-328 Impairs the Cell Cycle in Zebrafish (Danio rerio) by Inhibiting the p38 MAPK/p53/Gadd45a Signaling Pathway.

Zhang L, Shen L, Huang Y, Cui S, Zhao Q, Zhang C, Zhuang S, Jiang G
Environmental science & technology 2023 Jul 11;57(27):9965-9974

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Protective Effect of Water-Soluble Acacetin Prodrug on APAP-Induced Acute Liver Injury Is Associated with Upregulation of PPARγ and Alleviation of ER Stress.

Miao J, Yao S, Sun H, Jiang Z, Gao Z, Xu J, Chen K
International journal of molecular sciences 2023 Jul 11;24(14)

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Lysophosphatidic acid is associated with oocyte maturation by enhancing autophagy via PI3K-AKT-mTOR signaling pathway in granulosa cells.

Liu J, Wang C
Journal of ovarian research 2023 Jul 11;16(1):137

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Antiandrogen treatment induces stromal cell reprogramming to promote castration resistance in prostate cancer.

Wang H, Li N, Liu Q, Guo J, Pan Q, Cheng B, Xu J, Dong B, Yang G, Yang B, Wang X, Gu Y, Zhang G, Lian Y, Zhang W, Zhang M, Li T, Zang Y, Tan M, Li Q, Wang X, Yu Z, Jiang J, Huang H, Qin J
Cancer cell 2023 Jul 10;41(7):1345-1362.e9

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A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy.

Southwell N, Primiano G, Nadkarni V, Attarwala N, Beattie E, Miller D, Alam S, Liparulo I, Shurubor YI, Valentino ML, Carelli V, Servidei S, Gross SS, Manfredi G, Chen Q, D'Aurelio M
EMBO molecular medicine 2023 Jul 10;15(7):e16951

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γ-Bungarotoxin impairs the vascular endothelial barrier function by inhibiting integrin α5.

Chen W, Yu H, Sun C, Dong M, Zhao N, Wang Y, Yu K, Zhang J, Xu N, Liu W
Toxicology letters 2023 Jul 1;383:177-191

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Periplocin inhibits hepatocellular carcinoma progression and reduces the recruitment of MDSCs through AKT/NF-κB pathway.

Lin JP, Huang MH, Sun ZT, Chen L, Lei YH, Huang YQ, Qi M, Fan SR, Chen SG, Chung CW, Chan MC, Liu JS, Hu M, Chen MF, Ye WC, Chen YY, Deng LJ
Life sciences 2023 Jul 1;324:121715

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Lysine crotonylation of SERCA2a correlates to cardiac dysfunction and arrhythmia in Sirt1 cardiac-specific knockout mice.

Chen HX, Wang XC, Hou HT, Wang J, Yang Q, Chen YL, Chen HZ, He GW
International journal of biological macromolecules 2023 Jul 1;242(Pt 4):125151

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Angelica sinensis aboveground part polysaccharide and its metabolite 5-MT ameliorate colitis via modulating gut microbiota and TLR4/MyD88/NF-κB pathway.

Zou YF, Li CY, Fu YP, JiZe XP, Zhao YZ, Peng X, Wang JY, Yin ZQ, Li YP, Song X, Li LX, Zhao XH, Feng B, Huang C, Ye G, Tang HQ, Chen J, Li R, Chen XF, Tian ML
International journal of biological macromolecules 2023 Jul 1;242(Pt 1):124689

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An enzyme-instructed self-assembly system induces tumor acidosis via sequential-dual effect for cancer selective therapy.

Zhang H, Wang Z, Gao T, Wang Z, Ren C, Liu J
Acta biomaterialia 2023 Jul 1;164:447-457

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Integrating network pharmacology and experimental verification to explore the pharmacological mechanisms of asparagus against polycystic ovary syndrome.

Xing J, Luo X, Jia K, Liu S, Chen S, Qiao G, Zhang C, Yi J
Journal of ovarian research 2023 Jul 1;16(1):128

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KLF6 alleviates hepatic ischemia-reperfusion injury by inhibiting autophagy.

Li J, Yu D, He C, Yu Q, Huo Z, Zhang Y, Zhang S
Cell death & disease 2023 Jul 1;14(7):393

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Heme oxygenase-1 protects against PM2.5 induced endothelial dysfunction through inhibition of HIF1α.

Xu H, Wen Q, Xu X, Yu D, Liu Z, Zhang C, Zhang X, Ma J, Zhao H, Song L
Environmental toxicology and pharmacology 2023 Jan;97:104024

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Direct administration of mesenchymal stem cell-derived mitochondria improves cardiac function after infarction via ameliorating endothelial senescence.

Liang X, Zhang Y, Lin F, Li M, Li X, Chen Y, Liu J, Meng Q, Ma X, Wang E, Wei L, He Z, Fan H, Zhou X, Ding Y, Liu Z
Bioengineering & translational medicine 2023 Jan;8(1):e10365

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Tanshinone functions as a coenzyme that confers gain of function of NQO1 to suppress ferroptosis.

Wang TX, Duan KL, Huang ZX, Xue ZA, Liang JY, Dang Y, Zhang A, Xiong Y, Ding C, Guan KL, Yuan HX
Life science alliance 2023 Jan;6(1)

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Gomphrena globosa L. extract alleviates carbon tetrachoride-induced liver injury in mice by activating antioxidant signaling pathways and promoting autophagy.

Wei Y, Tan W, Qin H, Jin M, Yu H, Cheng J, Feng H
Molecular biology reports 2023 Jan;50(1):97-106

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Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.

Yang Z, Yan C, Ma J, Peng P, Ren X, Cai S, Shen X, Wu Y, Zhang S, Wang X, Qiu S, Zhou J, Fan J, Huang H, Gao Q
Nature metabolism 2023 Jan;5(1):61-79

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LncRNA LINC00534 regulates cell proliferation and migration via the miR-494-3p/PTEN axis in HTR-8/SVneo cells.

Song X, Zhang X, Xia Q, Li C, Zhang Y, Huang Y, Meng L, Wang C, Li J, Long W
Journal of clinical laboratory analysis 2023 Jan;37(1):e24802

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VASN promotes colorectal cancer progression by activating the YAP/TAZ and AKT signaling pathways via YAP.

Liang W, Zuo J, Liu M, Su Y, Guo B, Hou J, Xing Q, Peng Y, Fang L, Cao Y, Shan J, Sun R, Zhao J, Wang J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Jan;37(1):e22688

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6-Methoxydihydrosanguinarine induces apoptosis and autophagy in breast cancer MCF-7 cells by accumulating ROS to suppress the PI3K/AKT/mTOR signaling pathway.

Zhang L, Zhang X, Che D, Zeng L, Zhang Y, Nan K, Zhang X, Zhang H, Guo Z
Phytotherapy research : PTR 2023 Jan;37(1):124-139

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Neuroprotective effect of meglumine cyclic adenylate against ischemia/reperfusion injury via STAT3-Ser727 phosphorylation.

Niu XQ, Li DD, Bao YJ, Yang Q, Liu YK, Lu F, Yan JZ, Yin XH, Li C
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2023 Jan;32(1):106892

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N(6)-Methyladenosine-modified lncRNA LINREP promotes Glioblastoma progression by recruiting the PTBP1/HuR complex.

Ji X, Liu Z, Gao J, Bing X, He D, Liu W, Wang Y, Wei Y, Yin X, Zhang F, Han M, Lu X, Wang Z, Liu Q, Xin T
Cell death and differentiation 2023 Jan;30(1):54-68

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Bud31-mediated alternative splicing is required for spermatogonial stem cell self-renewal and differentiation.

Qin J, Huang T, Wang Z, Zhang X, Wang J, Dang Q, Cui D, Wang X, Zhai Y, Zhao L, Lu G, Shao C, Li S, Liu H, Liu Z
Cell death and differentiation 2023 Jan;30(1):184-194

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FAAH served a key membrane-anchoring and stabilizing role for NLRP3 protein independently of the endocannabinoid system.

Zhu Y, Zhang H, Mao H, Zhong S, Huang Y, Chen S, Yan K, Zhao Z, Hao X, Zhang Y, Yao H, Huang X, Wang M, Zhang W, Li J, Meng G, Qin X, Ye Z, Shen J, Song Y, Xu Y, Yang Z, Wang L, Zhang Y, Wen L
Cell death and differentiation 2023 Jan;30(1):168-183

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Quantitative reactive cysteinome profiling reveals a functional link between ferroptosis and proteasome-mediated degradation.

Wang Y, Wang C
Cell death and differentiation 2023 Jan;30(1):125-136

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Remodeling of imbalanced extracellular matrix homeostasis for reversal of pancreatic fibrosis.

Qi L, Han H, Han MM, Sun Y, Xing L, Jiang HL, Pandol SJ, Li L
Biomaterials 2023 Jan;292:121945

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Dexmedetomidine attenuates airway inflammation and oxidative stress in asthma via the Nrf2 signaling pathway.

Xiao S, Zhou Y, Gao H, Yang D
Molecular medicine reports 2023 Jan;27(1)

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Metabolomic analysis and pharmacological validation of the cerebral protective effect of 3,4‑dihydroxybenzaldehyde on cerebral ischemia‑reperfusion injury.

Luo Y, Chen P, Yang L, Duan X
Molecular medicine reports 2023 Jan;27(1)

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Chloride intracellular channel 1 promotes esophageal squamous cell carcinoma proliferation via mTOR signalling.

Geng H, Feng C, Sun Z, Fan X, Xie Y, Gu J, Fan L, Liu G, Li C, Thorne RF, Zhang XD, Li X, Liu X
Translational oncology 2023 Jan;27:101560

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FXR1 promotes proliferation, invasion and migration of hepatocellular carcinoma in vitro and in vivo.

Zhao K, Gao J, Shi J, Shi C, Pang C, Li J, Guo W, Zhang S
Oncology letters 2023 Jan;25(1):22

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RBM24 inhibits the translation of SARS-CoV-2 polyproteins by targeting the 5'-untranslated region.

Yao Y, Sun H, Chen Y, Tian L, Huang D, Liu C, Zhou Y, Wang Y, Wen Z, Yang B, Chen X, Pei R
Antiviral research 2023 Jan;209:105478

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Upregulation of PIK3IP1 monitors the anti-cancer activity of PI3Kα inhibitors in gastric cancer cells.

Ma XB, Wang Y, Jia YJ, Liu YJ, Tian YQ, Liu Y, Hou GQ, Xu YC, Liu HM
Biochemical pharmacology 2023 Jan;207:115380

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Southern rice black-streaked dwarf virus induces incomplete autophagy for persistence in gut epithelial cells of its vector insect.

Zhang L, Liu W, Wu N, Wang H, Zhang Z, Liu Y, Wang X
PLoS pathogens 2023 Jan;19(1):e1011134

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c-kit(+)VEGFR-2(+) Mesenchymal Stem Cells Differentiate into Cardiovascular Cells and Repair Infarcted Myocardium after Transplantation.

Zhou P, Yu SN, Zhang HF, Wang YL, Tao P, Tan YZ, Wang HJ
Stem cell reviews and reports 2023 Jan;19(1):230-247

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Exosomal microRNA-4535 of Melanoma Stem Cells Promotes Metastasis by Inhibiting Autophagy Pathway.

Liu D, Li X, Zeng B, Zhao Q, Chen H, Zhang Y, Chen Y, Wang J, Xing HR
Stem cell reviews and reports 2023 Jan;19(1):155-169

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Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine.

Wang SM, Wu HE, Yasui Y, Geva M, Hayden M, Maurice T, Cozzolino M, Su TP
Autophagy 2023 Jan;19(1):126-151

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T-cell immunoglobulin- and mucin-domain-containing molecule-4 maintains adipose tissue homeostasis by orchestrating M2 macrophage polarization via nuclear factor kappa B pathway.

Ding L, Liang Y, Wang Y, Tong Z, Liu W, Tan S, Zhang J, Wang Y, Wu Z, Liang X, Ma C, Gao L
Immunology 2023 Jan;168(1):49-62

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Exosomal miR-543 derived from umbilical cord mesenchymal stem cells ameliorates endometrial fibrosis in intrauterine adhesion via downregulating N-cadherin.

Yuan D, Guo T, Qian H, Jin C, Ge H, Zhao Y, Zhu D, Lin M, Wang H, Yu H
Placenta 2023 Jan;131:75-81

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Flavonoids dimers from the fruits of Psoralea corylifolia and their cytotoxicity against MCF-7 cells.

Xu QX, Wang ZJ, He ZC, Xu J, Xu W, Yang XW
Bioorganic chemistry 2023 Jan;130:106262

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Downregulation of CBX7 induced by EZH2 upregulates FGFR3 expression to reduce sensitivity to cisplatin in bladder cancer.

Ren J, Yu H, Li W, Jin X, Yan B
British journal of cancer 2023 Jan;128(2):232-244

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Amyloid β oligomers disrupt piriform cortical output via a serotonergic pathway.

Wang X, Hu M, Xie Q, Geng C, Jin C, Ren W, Fan J, Ma T, Hu B
Neurobiology of aging 2023 Jan;121:64-77

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Banoxantrone Coordinated Metal-Organic Framework for Photoacoustic Imaging-Guided High Intensity Focused Ultrasound Therapy.

Sun T, Li J, Zeng C, Luo C, Luo X, Li H
Advanced healthcare materials 2023 Jan;12(2):e2202348

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Methotrexate and Triptolide regulate Notch signaling pathway by targeting the Nedd4-Numb axis.

Wu Q, Chen X, Qiao C, Cao X, Du Q, Yuan Y, Zuo Y, Miao Y, Zheng Z, Zhang T, Zang L, Yang X, Shi W, Xie Z, Xu Y, Wu D, Wen C, Zheng H
International immunopharmacology 2023 Jan;114:109595

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IL-33/ST2 axis promotes remodeling of the extracellular matrix and drives protective microglial responses in the mouse model of perioperative neurocognitive disorders.

Li S, Liu H, Qian Y, Jiang L, Liu S, Liu Y, Liu C, Gu X
International immunopharmacology 2023 Jan;114:109479

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Identification and characterization of novel carboxyl ester lipase gene variants in patients with different subtypes of diabetes.

Wu H, Shu M, Liu C, Zhao W, Li Q, Song Y, Zhang T, Chen X, Shi Y, Shi P, Fang L, Wang R, Xu C
BMJ open diabetes research & care 2023 Jan;11(1)

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Alantolactone induces concurrent apoptosis and GSDME-dependent pyroptosis of anaplastic thyroid cancer through ROS mitochondria-dependent caspase pathway.

Hu Y, Wen Q, Cai Y, Liu Y, Ma W, Li Q, Song F, Guo Y, Zhu L, Ge J, Zeng Q, Wang J, Yin C, Zheng G, Ge M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;108:154528

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Phosphoglycerate mutase 5 initiates inflammation in acute kidney injury by triggering mitochondrial DNA release by dephosphorylating the pro-apoptotic protein Bax.

Li J, Sun X, Yang N, Ni J, Xie H, Guo H, Wang X, Zhou L, Liu J, Chen S, Wang X, Zhang Y, Yu C, Zhang W, Lu L
Kidney international 2023 Jan;103(1):115-133

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Sclareol ameliorates liver injury by inhibiting nuclear factor-kappa B/NOD-like receptor protein 3-mediated inflammation and lipid metabolism disorder in diabetic mice.

Tang L, Mei X, Ye M, Liu Y, Huang Y, Yu J, Zhang L, Zhuge S, Jiang G, Zhu J
International journal of immunopathology and pharmacology 2023 Jan-Dec;37:3946320231223644

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Boswellic acid coated zinc nanoparticles attenuate NF-κB-mediated inflammation in DSS-induced ulcerative colitis in rats.

Abou Zaid ES, Mansour SZ, El-Sonbaty SM, Moawed FS, Kandil EI, Haroun RA
International journal of immunopathology and pharmacology 2023 Jan-Dec;37:3946320221150720

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CD27-Expressing Xenoantigen-Expanded Human Regulatory T Cells Are Efficient in Suppressing Xenogeneic Immune Response.

Cao L, Ma X, Zhang J, Yang M, He Z, Yang C, Li S, Rong P, Wang W
Cell transplantation 2023 Jan-Dec;32:9636897221149444

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BDNF-TrkB signaling pathway-mediated microglial activation induces neuronal KCC2 downregulation contributing to dynamic allodynia following spared nerve injury.

Hu Z, Yu X, Chen P, Jin K, Zhou J, Wang G, Yu J, Wu T, Wang Y, Lin F, Zhang T, Wang Y, Zhao X
Molecular pain 2023 Jan-Dec;19:17448069231185439

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Study on the treatment of postmenopausal osteoporosis with quercetin in Liuwei Dihuang Pill based on network pharmacology.

Zhu F, Li W, Wang L, Dai B, Liu Z, Wu H, Deng T
Journal of orthopaedic surgery and research 2023 Jan 9;18(1):21

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iTRAQ-based Proteomic Analysis Unveils ACSL4 as a Novel Potential Regulator of Human Endometrial Receptivity.

Hu S, Sun Z, Li B, Zhao H, Wang Y, Yao G, Li X, Bian X, Li TC, Vankelecom H, Sun Y
Endocrinology 2023 Jan 9;164(3)

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Virulence factors and mechanisms of paediatric pneumonia caused by Enterococcus faecalis.

Tian Z, Khan AI, Rehman AU, Deng T, Ma C, Wang L
Gut pathogens 2023 Jan 9;15(1):2

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The Mechanosensitive Ion Channel PIEZO1 in Intestinal Epithelial Cells Mediates Inflammation through the NOD-Like Receptor 3 Pathway in Crohn's Disease.

Liu Q, Wang D, Yang X, Ma F, Han W, Hu J, Mei Q
Inflammatory bowel diseases 2023 Jan 5;29(1):103-115

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A Mulberry Diels-Alder-Type Adduct, Kuwanon M, Triggers Apoptosis and Paraptosis of Lung Cancer Cells through Inducing Endoplasmic Reticulum Stress.

Ma M, Luan X, Zheng H, Wang X, Wang S, Shen T, Ren D
International journal of molecular sciences 2023 Jan 5;24(2)

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PRPF19 Limits Porcine Epidemic Diarrhea Virus Replication through Targeting and Degrading Viral Capsid Protein.

Zhai X, Kong N, Wang C, Qin W, Dong S, Zhai H, Yang X, Ye C, Ye M, Li G, Tong W, Liu C, Zheng H, Yu H, Zhang W, Yang X, Tong G, Shan T
Journal of virology 2023 Jan 31;97(1):e0161422

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SLC7A14 imports GABA to lysosomes and impairs hepatic insulin sensitivity via inhibiting mTORC2.

Jiang X, Liu K, Jiang H, Yin H, Wang ED, Cheng H, Yuan F, Xiao F, Wang F, Lu W, Peng B, Shu Y, Li X, Chen S, Guo F
Cell reports 2023 Jan 31;42(1):111984

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A role of cytoplasmic p53 in the regulation of metabolism shown by bat-mimicking p53 NLS mutant mice.

Sanford JD, Jin A, Grois GA, Zhang Y
Cell reports 2023 Jan 31;42(1):111920

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The deubiquitinase OTUD1 noncanonically suppresses Akt activation through its N-terminal intrinsically disordered region.

Fan G, Wang F, Chen Y, Zheng Q, Xiong J, Lv Q, Wu K, Xiong J, Wei L, Li D, Zhang J, Zhang W, Li F
Cell reports 2023 Jan 31;42(1):111916

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Jinhua Qinggan granules attenuates acute lung injury by promotion of neutrophil apoptosis and inhibition of TLR4/MyD88/NF-κB pathway.

Zhu Y, Han Q, Wang L, Wang B, Chen J, Cai B, Wu C, Zhu X, Liu F, Han D, Dong H, Jia Y, Liu Y
Journal of ethnopharmacology 2023 Jan 30;301:115763

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Alteration in branching morphogenesis via YAP/TAZ in fibroblasts of fetal lungs in an LPS-induced inflammation model.

Ko HS, Laiman V, Tsao PN, Chen CM, Chuang HC
Molecular medicine (Cambridge, Mass.) 2023 Jan 30;29(1):16

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FTO-dependent m(6)A modification of Plpp3 in circSCMH1-regulated vascular repair and functional recovery following stroke.

Li B, Xi W, Bai Y, Liu X, Zhang Y, Li L, Bian L, Liu C, Tang Y, Shen L, Yang L, Gu X, Xie J, Zhou Z, Wang Y, Yu X, Wang J, Chao J, Han B, Yao H
Nature communications 2023 Jan 30;14(1):489

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LncRNA WDR11-AS1 Promotes Extracellular Matrix Synthesis in Osteoarthritis by Directly Interacting with RNA-Binding Protein PABPC1 to Stabilize SOX9 Expression.

Huang H, Yan J, Lan X, Guo Y, Sun M, Zhao Y, Zhang F, Sun J, Lu S
International journal of molecular sciences 2023 Jan 3;24(1)

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Ketogenic Diet Combined with Moderate Aerobic Exercise Training Ameliorates White Adipose Tissue Mass, Serum Biomarkers, and Hepatic Lipid Metabolism in High-Fat Diet-Induced Obese Mice.

Yan J, Ren C, Dong Y, Wali JA, Song H, Zhang Y, Zhang H, Kou G, Raubenheimer D, Cui Z
Nutrients 2023 Jan 3;15(1)

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Vacuole Membrane Protein 1 (VMP1) Restricts NLRP3 Inflammasome Activation by Modulating SERCA Activity and Autophagy.

Zack SR, Nikolaienko R, Cook B, Melki R, Zima AV, Campbell EM
Research square 2023 Jan 27;

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Identification of the Acid-Sensitive Site Critical for Chloral Hydrate (CH) Activation of the Proton-Activated Chloride Channel.

Xu XY, Zhang FF, Gan J, Zhang MY, Shen ZS, Guo Q, Teng Y, Ji JW, Cao JL, Tang QY, Zhang Z
The Journal of neuroscience : the official journal of the Society for Neuroscience 2023 Jan 25;43(4):526-539

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Activation of NLRP3 inflammasome in lung epithelial cells triggers radiation-induced lung injury.

Rao X, Zhou D, Deng H, Chen Y, Wang J, Zhou X, Jie X, Xu Y, Wu Z, Wang G, Dong X, Zhang S, Meng R, Wu C, Xing S, Fan K, Wu G, Zhou R
Respiratory research 2023 Jan 24;24(1):25

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Membrane-dependent actin polymerization mediated by the Legionella pneumophila effector protein MavH.

Zhang Q, Wan M, Mao Y
bioRxiv : the preprint server for biology 2023 Jan 24;

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LIPUS accelerates bone regeneration via HDAC6-mediated ciliogenesis.

Xiao H, Yan A, Li M, Wang L, Xiang J
Biochemical and biophysical research communications 2023 Jan 22;641:34-41

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TRIM15 forms a regulatory loop with the AKT/FOXO1 axis and LASP1 to modulate the sensitivity of HCC cells to TKIs.

Yang C, Jin X, Liu X, Wu G, Yang W, Pang B, Jiang J, Liao D, Zhang Y
Cell death & disease 2023 Jan 20;14(1):47

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PHB2 promotes colorectal cancer cell proliferation and tumorigenesis through NDUFS1-mediated oxidative phosphorylation.

Ren L, Meng L, Gao J, Lu M, Guo C, Li Y, Rong Z, Ye Y
Cell death & disease 2023 Jan 20;14(1):44

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Photobiomodulation promotes spinal cord injury repair by inhibiting macrophage polarization through lncRNA TUG1-miR-1192/TLR3 axis.

Ju C, Ma Y, Zuo X, Wang X, Song Z, Zhang Z, Zhu Z, Li X, Liang Z, Ding T, Hu X, Wang Z
Cellular & molecular biology letters 2023 Jan 19;28(1):5

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The role of atypical MAP kinase 4 in the host interaction with Cryptosporidium parvum.

Watanabe N, Bando H, Murakoshi F, Sakurai R, Kabir MHB, Fukuda Y, Kato K
Scientific reports 2023 Jan 19;13(1):1096

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Long noncoding RNA uc007nnj.1 mediates neuronal death induced by retinal ischemia/reperfusion in mice via the miR-155-5p/Tle4 axis.

Feng Y, Lu J, Peng X, Ge Y, Zhang R, Li H
Molecular medicine (Cambridge, Mass.) 2023 Jan 18;29(1):9

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Structural basis of bacterial effector protein azurin targeting tumor suppressor p53 and inhibiting its ubiquitination.

Hu J, Jiang W, Zuo J, Shi D, Chen X, Yang X, Zhang W, Ma L, Liu Z, Xing Q
Communications biology 2023 Jan 17;6(1):59

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The natural flavone acacetin protects against high-fat diet-induced lipid accumulation in the liver via the endoplasmic reticulum stress/ferroptosis pathway.

Jiang Z, Sun H, Miao J, Sheng Q, Xu J, Gao Z, Zhang X, Song Y, Chen K
Biochemical and biophysical research communications 2023 Jan 15;640:183-191

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Knockdown of PKMYT1 is associated with autophagy inhibition and apoptosis induction and suppresses tumor progression in hepatocellular carcinoma.

Wu F, Tu C, Zhang K, Che H, Lin Q, Li Z, Zhou Q, Tang B, Yang Y, Chen M, Shao C
Biochemical and biophysical research communications 2023 Jan 15;640:173-182

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Novel insights into the mediating roles of cluster of differentiation 36 in transmembrane transport and tissue partition of per- and polyfluoroalkyl substances in mice.

Jia Y, Zhu Y, Wang R, Ye Q, Xu D, Zhang W, Zhang Y, Shan G, Zhu L
Journal of hazardous materials 2023 Jan 15;442:130129

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Inhibition of cGAS ameliorates acute lung injury triggered by zinc oxide nanoparticles.

Jiang Z, Jiang Y, Fan J, Zhang J, Xu G, Fan Y, Zhang L, Qin X, Jiang X, Mao L, Liu G, Chen C, Zou Z
Toxicology letters 2023 Jan 15;373:62-75

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BAP31 regulates the expression of ICAM-1/VCAM-1 via MyD88/NF-κB pathway in acute lung injury mice model.

Li G, Jiang X, Liang X, Hou Y, Zang J, Zhu B, Jia C, Niu K, Liu X, Xu X, Jiang R, Wang B
Life sciences 2023 Jan 15;313:121310

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Targeting TRMT5 suppresses hepatocellular carcinoma progression via inhibiting the HIF-1α pathways.

Zhao Q, Zhang L, He Q, Chang H, Wang Z, Cao H, Zhou Y, Pan R, Chen Y
Journal of Zhejiang University. Science. B 2023 Jan 15;24(1):50-63

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The U2AF65/circNCAPG/RREB1 feedback loop promotes malignant phenotypes of glioma stem cells through activating the TGF-β pathway.

Li H, Jiang Y, Hu J, Xu J, Chen L, Zhang G, Zhao J, Zong S, Guo Z, Li X, Zhao X, Jing Z
Cell death & disease 2023 Jan 13;14(1):23

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Flavivirus prM interacts with MDA5 and MAVS to inhibit RLR antiviral signaling.

Sui L, Zhao Y, Wang W, Chi H, Tian T, Wu P, Zhang J, Zhao Y, Wei ZK, Hou Z, Zhou G, Wang G, Wang Z, Liu Q
Cell & bioscience 2023 Jan 13;13(1):9

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Betulinaldehyde exhibits effective anti-tumor effects in A549 cells by regulating intracellular autophagy.

Huang PH, Duan XB, Tang ZZ, Zou ZX, Song WM, Gao G, Li D, Nie FQ, Yan X, Fu YX, Guo R, Xu YY
Scientific reports 2023 Jan 13;13(1):743

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Discovery of rafoxanide as a novel agent for the treatment of non-small cell lung cancer.

Hu A, Liu J, Wang Y, Zhang M, Guo Y, Qin Y, Liu T, Men Y, Chen Q, Liu T
Scientific reports 2023 Jan 13;13(1):693

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Crizotinib Nanomicelles Synergize with Chemotherapy through Inducing Proteasomal Degradation of Mutp53 Proteins.

Yi T, Qian J, Ye Y, Zhang H, Jin X, Wang M, Yang Z, Zhang W, Wen L, Zhang Y
ACS applied materials & interfaces 2023 Jan 11;15(1):511-523

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PFC@O(2) Targets HIF-1α to Reverse the Immunosuppressive TME in OSCC.

Lan Z, Zou KL, Cui H, Chen H, Zhao YY, Yu GT
Journal of clinical medicine 2023 Jan 10;12(2)

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Dioscin reduced chemoresistance for colon cancer and analysis of sensitizing targets.

Li R, Qin J, Wang Z, Lv F, Guo J, Zhu H, Huang Y
Biochemical and biophysical research communications 2023 Jan 1;638:94-102

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Ablation of AQP5 gene in mice leads to olfactory dysfunction caused by hyposecretion of Bowman's gland.

Zhao X, Liu G, Yu X, Yang X, Gao W, Zhao Z, Ma T, Ma J
Chemical senses 2023 Jan 1;48

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Toxicity of polystyrene nanoparticles for mouse ovary and cultured human granulosa cells.

Huang J, Zou L, Bao M, Feng Q, Xia W, Zhu C
Ecotoxicology and environmental safety 2023 Jan 1;249:114371

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A Prevascularized Sinus Tract on the Liver Surface for Islet Transplantation.

Li F, Lv Y, Li X, Yang Z, Guo T, Zhang J
Transplantation 2023 Jan 1;107(1):117-128

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M2 macrophages with inflammation tropism facilitate cementoblast mineralization.

Huang X, Wang X, Ma L, Wang H, Peng Y, Liu H, Xiao J, Cao Z
Journal of periodontology 2023 Feb;94(2):290-300

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Luteolin improves vasoconstriction function and survival of septic mice via AMPK/NF-κB pathway.

Liu B, Su H
Heliyon 2023 Feb;9(2):e13330

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Triptonide inhibits growth and metastasis in HCC by suppressing EGFR/PI3K/AKT signaling.

Zhang H, Mao Y, Zou X, Niu J, Jiang J, Chen X, Zhu M, Yang X, Dong T
Neoplasma 2023 Feb;70(1):94-102

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CRISPR-Cas9-Mediated NPC1 Gene Deletion Enhances HEK 293 T Cell Adhesion by Regulating E-Cadherin.

Jia Z, Yang M, Zhao Y, Li X, Yang C, Qiao L, Li H, Du J, Lin J, Guan L
Molecular biotechnology 2023 Feb;65(2):252-262

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Moderate-Intensity Treadmill Exercise Promotes mTOR-Dependent Motor Cortical Neurotrophic Factor Expression and Functional Recovery in a Murine Model of Crush Spinal Cord Injury (SCI).

Zhan Z, Pan L, Zhu Y, Wang Y, Zhao Q, Liu Y, Li S, Wang H, Yang C, Yu L, Yin Y, Tan B
Molecular neurobiology 2023 Feb;60(2):960-978

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Disrupted in renal carcinoma 2 (DIRC2/SLC49A4) is an H(+)-driven lysosomal pyridoxine exporter.

Akino S, Yasujima T, Yamashiro T, Yuasa H
Life science alliance 2023 Feb;6(2)

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The role of Sirt3-induced autophagy in renal structural damage caused by periodontitis in rats.

Ding X, Hou Y, Liu X, Li X, Liu X, Deng Y, Cao N, Yu W
Journal of periodontal research 2023 Feb;58(1):97-108

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Cul5 mediates taurine-stimulated mTOR mRNA expression and proliferation of mouse mammary epithelial cells.

Xu M, Zhou Y, Fan S, Zhang M, Gao X
Amino acids 2023 Feb;55(2):243-252

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Fc receptor-like 1 (FCRL1) is a novel biomarker for prognosis and a possible therapeutic target in diffuse large B-cell lymphoma.

Yousefi Z, Sharifzadeh S, Zare F, Eskandari N
Molecular biology reports 2023 Feb;50(2):1133-1145

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Extracellular acidosis restricts one-carbon metabolism and preserves T cell stemness.

Cheng H, Qiu Y, Xu Y, Chen L, Ma K, Tao M, Frankiw L, Yin H, Xie E, Pan X, Du J, Wang Z, Zhu W, Chen L, Zhang L, Li G
Nature metabolism 2023 Feb;5(2):314-330

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POU Domain Class 2 Transcription Factor 2 Inhibits Ferroptosis in Cerebral Ischemia Reperfusion Injury by Activating Sestrin2.

Yang J, Guo Q, Wang L, Yu S
Neurochemical research 2023 Feb;48(2):658-670

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MiR-29c Inhibits TNF-α-Induced ROS Production and Apoptosis in Mouse Hippocampal HT22 Cell Line.

Li B, Lu Y, Wang R, Xu T, Lei X, Jin H, Gao X, Xie Y, Liu X, Zeng J
Neurochemical research 2023 Feb;48(2):519-536

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Anti-inflammatory effects of extracellular vesicles from Morchella on LPS-stimulated RAW264.7 cells via the ROS-mediated p38 MAPK signaling pathway.

Chen Q, Che C, Yang S, Ding P, Si M, Yang G
Molecular and cellular biochemistry 2023 Feb;478(2):317-327

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PKMYT1 inhibits lung adenocarcinoma progression by abrogating AKT1 activity.

Wang S, Liu X, Zhou T, Li J, Lin Y, Zhou A, Huang J, Zhao J, Cai J, Cai X, Huang Y, Li X
Cellular oncology (Dordrecht, Netherlands) 2023 Feb;46(1):195-209

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Oligosaccharide Blocks PAR1 (Proteinase-Activated Receptor 1)-PAR4-Mediated Platelet Activation by Binding to Thrombin Exosite II and Impairs Thrombosis.

Li S, Wang W, Lin L, Yang L, Cai Y, Yang X, Zhang T, Xiao C, Yan H, Gao N, Zhao J
Arteriosclerosis, thrombosis, and vascular biology 2023 Feb;43(2):253-266

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miR-34b-3p Inhibition of eIF4E Causes Post-stroke Depression in Adult Mice.

Ke X, Deng M, Wu Z, Yu H, Yu D, Li H, Lu Y, Shu K, Pei L
Neuroscience bulletin 2023 Feb;39(2):194-212

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The cytotoxicity of zinc oxide nanoparticles to 3D brain organoids results from excessive intracellular zinc ions and defective autophagy.

Liu L, Wang J, Zhang J, Huang C, Yang Z, Cao Y
Cell biology and toxicology 2023 Feb;39(1):259-275

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STAT3/Mitophagy Axis Coordinates Macrophage NLRP3 Inflammasome Activation and Inflammatory Bone Loss.

Zhu L, Wang Z, Sun X, Yu J, Li T, Zhao H, Ji Y, Peng B, Du M
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2023 Feb;38(2):335-353

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Bone marrow mesenchymal stem cells repair hexavalent chromium-induced testicular injury by regulating autophagy and ferroptosis mediated by the AKT/mTOR pathway in rats.

Zhuge R, Li Z, He C, Ma W, Yan J, Xue Q, Wang R, Liu Y, Lu R, Du H, Yin F, Guo L
Environmental toxicology 2023 Feb;38(2):289-299

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Ubiquitin-specific protease 24 promotes EV71 infection by restricting K63-linked polyubiquitination of TBK1.

Zang L, Gu J, Yang X, Yuan Y, Guo H, Zhou W, Ma J, Chen Y, Wu Y, Zheng H, Shi W
Virologica Sinica 2023 Feb;38(1):75-83

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Paeoniflorin-6'-O-benzene sulfonate protected the intestinal epithelial barrier by restoring the inhibitory effect of GRK2 and β-arrestin 2 on ERK1/2-NF-κB.

Jiang M, Tang C, Yang M, Li Y, Wang W, Wang C, Wei W, Chen J
Phytotherapy research : PTR 2023 Feb;37(2):743-758

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N(6)-methyladenosine-modified USP13 induces pro-survival autophagy and imatinib resistance via regulating the stabilization of autophagy-related protein 5 in gastrointestinal stromal tumors.

Gao Z, Li C, Sun H, Bian Y, Cui Z, Wang N, Wang Z, Yang Y, Liu Z, He Z, Li B, Li F, Li Z, Wang L, Zhang D, Yang L, Xu Z, Li X, Xu H
Cell death and differentiation 2023 Feb;30(2):544-559

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Forced activation of dystrophin transcription by CRISPR/dCas9 reduced arrhythmia susceptibility via restoring membrane Nav1.5 distribution.

Zhang R, Liu J, Xue G, Yang J, Li D, Tian T, Zhang X, Gao K, Pan Z
Gene therapy 2023 Feb;30(1-2):142-149

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TIPE1 promotes liver regeneration by enhancing ROS-FoxO1 axis mediated autophagy.

Zhang X, Li S, Ren X, Xiang P, Zhang Y, Wang T, Qin Q, Sun F, Liu J, Gao L, Ma C, Yue X, Yang X, Han S, Liang X
The FEBS journal 2023 Feb;290(4):1117-1133

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Landscape of pathogenic mutations in premature ovarian insufficiency.

Ke H, Tang S, Guo T, Hou D, Jiao X, Li S, Luo W, Xu B, Zhao S, Li G, Zhang X, Xu S, Wang L, Wu Y, Wang J, Zhang F, Qin Y, Jin L, Chen ZJ
Nature medicine 2023 Feb;29(2):483-492

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KIAA1199 promotes oxaliplatin resistance and epithelial mesenchymal transition of colorectal cancer via protein O-GlcNAcylation.

Hua Q, Lu Y, Wang D, Da J, Peng W, Sun G, Gu K, Wang H, Zhu Y
Translational oncology 2023 Feb;28:101617

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Pirfenidone suppressed triple-negative breast cancer metastasis by inhibiting the activity of the TGF-β/SMAD pathway.

Luo D, Zeng X, Zhang S, Li D, Cheng Z, Wang Y, Long J, Hu Z, Long S, Zhou J, Zhang S, Zeng Z
Journal of cellular and molecular medicine 2023 Feb;27(3):456-469

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Role of SUMOylation of STAT1 in tubular epithelial‑mesenchymal transition induced by high glucose.

Gu C, Gao F, Zhang S, Kang L, Zhang W, Feng X, Liu J, Tian Y, Wei Q, Du Y, Xing Y, Liu Q, Liu S
Molecular medicine reports 2023 Feb;27(2)

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Mechanism of autophagy mediated by IGF-1 signaling pathway in the neurotoxicity of lead in pubertal rats.

Zhang B, Li H, Wang Y, Li Y, Zhou Z, Hou X, Zhang X, Liu T
Ecotoxicology and environmental safety 2023 Feb;251:114557

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YTHDF2 orchestrates tumor-associated macrophage reprogramming and controls antitumor immunity through CD8(+) T cells.

Ma S, Sun B, Duan S, Han J, Barr T, Zhang J, Bissonnette MB, Kortylewski M, He C, Chen J, Caligiuri MA, Yu J
Nature immunology 2023 Feb;24(2):255-266

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Mitochondrial targeting half-sandwich iridium(III) and ruthenium(II) dppf complexes and in vitro anticancer assay.

Liu J, Wu Y, Yang G, Liu Z, Liu X
Journal of inorganic biochemistry 2023 Feb;239:112069

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Inositol polyphosphates-regulated polyubiquitination of PHR1 by NLA E3 ligase during phosphate starvation response in Arabidopsis.

Park SH, Jeong JS, Huang CH, Park BS, Chua NH
The New phytologist 2023 Feb;237(4):1215-1228

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Effects of substrate topography on the regulation of human fibroblasts and capsule formation via modulating macrophage polarization.

Chen C, Chen Y, Lan YJ, Tian MN, Zhang YM, Lei ZY, Fan DL
Colloids and surfaces. B, Biointerfaces 2023 Feb;222:113086

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Barrier-penetrating liposome targeted delivery of basic fibroblast growth factor for spinal cord injury repair.

Wu F, Wang P, Wei X, Yang Y, Al Mamun A, Zhang X, Zhu Y, Mo T, Zhang H, Jiang C, Hu J, Xiao J
Materials today. Bio 2023 Feb;18:100546

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LncRNA NR2F1-AS1 was involved in azacitidine resistance of THP-1 cells by targeting IGF1 with miR-483-3p.

Hu C, Li S, Fu X, Zhao X, Peng J
Cytokine 2023 Feb;162:156105

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A biomaterial-based therapy using a sodium hyaluronate/bioglass composite hydrogel for the treatment of oral submucous fibrosis.

Guo ZX, Zhang Z, Yan JF, Xu HQ, Wang SY, Ye T, Han XX, Wang WR, Wang Y, Gao JL, Niu LN, Chang J, Jiao K
Acta biomaterialia 2023 Feb;157:639-654

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Hyperbaric oxygen enhanced the chemotherapy of mitochondrial targeting molecule IR-780 in bladder cancer.

Shen C, Yue X, Dai L, Wang J, Li J, Fang Q, Zhi Y, Shi C, Li W
Journal of cancer research and clinical oncology 2023 Feb;149(2):683-699

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Costunolide covalently targets NACHT domain of NLRP3 to inhibit inflammasome activation and alleviate NLRP3-driven inflammatory diseases.

Xu H, Chen J, Chen P, Li W, Shao J, Hong S, Wang Y, Chen L, Luo W, Liang G
Acta pharmaceutica Sinica. B 2023 Feb;13(2):678-693

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Identification of miR-30c-5p as a tumor suppressor by targeting the m(6) A reader HNRNPA2B1 in ovarian cancer.

Wu Q, Li G, Gong L, Cai J, Chen L, Xu X, Liu X, Zhao J, Zeng Y, Gao R, Yu L, Wang Z
Cancer medicine 2023 Feb;12(4):5055-5070

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Macrophage migration inhibitory factor (MIF) inhibitor iSO-1 promotes staphylococcal protein A-induced osteogenic differentiation by inhibiting NF-κB signaling pathway.

Shi X, Wu Y, Ni H, Li M, Qi B, Xu Y
International immunopharmacology 2023 Feb;115:109600

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Transcriptome analysis highlights the role of ferroptosis in palmitic acid-induced endothelial dysfunction.

Tan XH, Gu YY, Song WP, Nan TG, Song WD, Fang D, Yuan YM, Xin ZC, Li XS, Guan RL
Sexual medicine 2023 Feb;11(1):qfac008

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Sestrin2 contributes to BRAF inhibitor resistance via reducing redox vulnerability of melanoma cells.

Guo S, Yue Q, Wang S, Wang H, Ye Z, Zhang W, Shi Q, Gao T, Li C, Zhu G
Journal of dermatological science 2023 Feb;109(2):52-60

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Manipulation of PD-L1 Endosomal Trafficking Promotes Anticancer Immunity.

Ye Z, Xiong Y, Peng W, Wei W, Huang L, Yue J, Zhang C, Lin G, Huang F, Zhang L, Zheng S, Yue J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Feb;10(6):e2206411

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Low temperature exposure inhibits proliferation and induces apoptosis of bovine subcutaneous preadipocytes via p38 MAPK/JNK activation.

Li T, Bai H, Yang L, Hao W, Wei S, Yan P
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2023 Feb-Mar;264:110813

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The Prognostic Value and the Oncogenic and Immunological Roles of Vacuolar Protein Sorting Associated Protein 26 A in Pancreatic Adenocarcinoma.

Hou J, Wu H, Xu B, Shang J, Xu X, Li G, Zhang H, Zhang W, Deng Y, Hong X, Hu T, Zhang M, Zhan Y
International journal of molecular sciences 2023 Feb 9;24(4)

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Morphometric analysis of the size-adjusted linear dimensions of the skull landmarks revealed craniofacial dysmorphology in Mid1-cKO mice.

Liang Y, Song C, Li J, Li T, Zhang C, Zou Y
BMC genomics 2023 Feb 9;24(1):68

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Protective Effect of 20(S)-Protopanaxadiol on D-Gal-Induced Cognitively Impaired Mice Based on Its Target Protein Brain-type Creatine Kinase.

Zhang H, Chen F, Xu S, Zhang W, Li R, Yao Q, Zhao Y, Zhu Z, Chen L
Journal of agricultural and food chemistry 2023 Feb 8;

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Ginsenoside Rg3 Ameliorates DSS-Induced Colitis by Inhibiting NLRP3 Inflammasome Activation and Regulating Microbial Homeostasis.

Liu D, Tian Q, Liu K, Ren F, Liu G, Zhou J, Yuan L, Fang Z, Zou B, Wang S
Journal of agricultural and food chemistry 2023 Feb 8;

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Viral Hemorrhagic Septicemia Virus Activates Integrated Stress Response Pathway and Induces Stress Granules to Regulate Virus Replication.

Ramnani B, Powell S, Shetty AG, Manivannan P, Hibbard BR, Leaman DW, Malathi K
Viruses 2023 Feb 7;15(2)

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Myristic acid as a checkpoint to regulate STING-dependent autophagy and interferon responses by promoting N-myristoylation.

Jia M, Wang Y, Wang J, Qin D, Wang M, Chai L, Fu Y, Zhao C, Gao C, Jia J, Zhao W
Nature communications 2023 Feb 7;14(1):660

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Methyltransferase-like 3 aggravates endoplasmic reticulum stress in preeclampsia by targeting TMBIM6 in YTHDF2-dependent manner.

Chen Y, Liu X, Li L, He X, Zheng F, Zhang Y, Gao H, Jin Z, Wu D, Wang Q, Tao H, Zhao Y, Liu W, Zou L
Molecular medicine (Cambridge, Mass.) 2023 Feb 6;29(1):19

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Chromatin remodeler BRM is a key mediator of leucine-stimulated mTOR gene transcription in mouse mammary epithelial cells.

Ke C, Zhao S, Wang L, Zhang M, Gao X
Biochemical and biophysical research communications 2023 Feb 5;643:88-95

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Ang-(1-7)/MasR axis promotes functional recovery after spinal cord injury by regulating microglia/macrophage polarization.

Gu G, Zhu B, Ren J, Song X, Fan B, Ding H, Shang J, Wu H, Li J, Wang H, Li J, Wei Z, Feng S
Cell & bioscience 2023 Feb 4;13(1):23

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Ant-Neointimal Formation Effects of SLC6A6 in Preventing Vascular Smooth Muscle Cell Proliferation and Migration via Wnt/β-Catenin Signaling.

Rong Z, Li F, Zhang R, Niu S, Di X, Ni L, Liu C
International journal of molecular sciences 2023 Feb 3;24(3)

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Microglia PKM2 Mediates Neuroinflammation and Neuron Loss in Mice Epilepsy through the Astrocyte C3-Neuron C3R Signaling Pathway.

Li X, Zhou R, Peng H, Peng J, Li Q, Mei M
Brain sciences 2023 Feb 3;13(2)

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Cofilin promotes tau pathology in Alzheimer's disease.

Yan M, Tang L, Dai L, Lei C, Xiong M, Zhang X, He M, Tian Y, Xiong J, Ke W, Zhang Z, Zhang C, Deng X, Zhang Z
Cell reports 2023 Feb 28;42(2):112138

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E2F1 inhibits cellular senescence and promotes oxaliplatin resistance in colorectal cancer.

Gao H, Zhou F, Li R, Yuan J, Ye L
Annals of translational medicine 2023 Feb 28;11(4):185

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Naringenin is a Potential Immunomodulator for Inhibiting Liver Fibrosis by Inhibiting the cGAS-STING Pathway.

Chen L, Xia S, Wang S, Zhou Y, Wang F, Li Z, Li Y, Kong D, Zhang Z, Shao J, Xu X, Zhang F, Zheng S
Journal of clinical and translational hepatology 2023 Feb 28;11(1):26-37

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Lactobacillus johnsonii L531 Ameliorates Salmonella enterica Serovar Typhimurium Diarrhea by Modulating Iron Homeostasis and Oxidative Stress via the IRP2 Pathway.

Chen K, Wang J, Guo L, Wang J, Yang L, Hu T, Zhao Y, Wang X, Zhu Y
Nutrients 2023 Feb 23;15(5)

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Peroxiredoxin-6 Released by Astrocytes Contributes to Neuroapoptosis During Ischemia.

Hou JY, Zhou XL, Wang XY, Liang J, Xue Q
Neuroscience 2023 Feb 21;512:59-69

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Cyanidin-3-O-glucoside and protocatechuic acid alleviate heat stress-induced testicular damage.

Cai D, Li X, Xu Q, Li H, Liu R, Chen J, Jiang X, Sun J, Lai C, Bai W
Food & function 2023 Feb 21;14(4):2200-2211

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Synergistic effects of L-theanine and epigallocatechin gallate in alleviating ovalbumin allergy by regulating intestinal immunity through inhibition of mast cell degranulation.

Xu W, Song X, Qu Q, Gong Z, Xiao W
Food & function 2023 Feb 21;14(4):2059-2073

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TIM-4 orchestrates mitochondrial homeostasis to promote lung cancer progression via ANXA2/PI3K/AKT/OPA1 axis.

Wang Y, Wang Y, Liu W, Ding L, Zhang X, Wang B, Tong Z, Yue X, Li C, Xu L, Wu Z, Liang X, Ma C, Gao L
Cell death & disease 2023 Feb 20;14(2):141

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Enterococcus faecalis promotes the progression of colorectal cancer via its metabolite: biliverdin.

Zhang L, Liu J, Deng M, Chen X, Jiang L, Zhang J, Tao L, Yu W, Qiu Y
Journal of translational medicine 2023 Feb 2;21(1):72

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Optimization of Primary Human Bronchial Epithelial 3D Cell Culture with Donor-Matched Fibroblasts and Comparison of Two Different Culture Media.

Maurer J, Walles T, Wiese-Rischke C
International journal of molecular sciences 2023 Feb 18;24(4)

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Circular RNA METTL9 contributes to neuroinflammation following traumatic brain injury by complexing with astrocytic SND1.

Huang C, Sun L, Xiao C, You W, Sun L, Wang S, Zhang Z, Liu S
Journal of neuroinflammation 2023 Feb 17;20(1):39

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Nanodrug rescues liver fibrosis via synergistic therapy with H(2)O(2) depletion and Saikosaponin b1 sustained release.

Dong H, Han X, Hao M, Yang Q, Lyu Q, Tang D, Shen Z, Wang K, Kuang H, Cao G, Peng M, Shao M
Communications biology 2023 Feb 16;6(1):184

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RGS12 represses oral squamous cell carcinoma by driving M1 polarization of tumor-associated macrophages via controlling ciliary MYCBP2/KIF2A signaling.

Yuan G, Yang S, Yang S
International journal of oral science 2023 Feb 16;15(1):11

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Thiram-induced hyperglycemia causes tibial dyschondroplasia by triggering aberrant ECM remodeling via the gut-pancreas axis in broiler chickens.

Mo Q, Kulyar MF, Quan C, Ding Y, Zhang Y, Zhang L, Pan H, Li J
Journal of hazardous materials 2023 Feb 15;444(Pt A):130368

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Disorders in the gut and liver are involved in depression contagion between isosexual post-stroke depression mice and the healthy cohabitors.

Wang H, Bin Wang, Pan MB, Jiang ST, Wang YC, Zhu Y, Zhang QC, Dong YF
Behavioural brain research 2023 Feb 15;439:114246

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Hexokinase 2-mediated glycolysis supports inflammatory responses to Porphyromonas gingivalis in gingival fibroblasts.

Su W, Li J, Jiang L, Lei L, Li H
BMC oral health 2023 Feb 15;23(1):103

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CMTM3 protects the gastric epithelial cells from apoptosis and promotes IL-8 by stabilizing NEMO during Helicobacter pylori infection.

Zhang J, Ning J, Fu W, Shi Y, Zhang J, Ding S
Gut pathogens 2023 Feb 13;15(1):6

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Exosomal lncRNA HOTAIR induces PDL1(+) B cells to impede anti-tumor immunity in colorectal cancer.

Xie Z, Xia J, Jiao M, Zhao P, Wang Z, Lin S, Xing Y, Li Y, Lu Z, Zhong Z, Miao C, Zhou P, Qian J, Wang L, Zhang D, Gu J, Chu Y, Liu R
Biochemical and biophysical research communications 2023 Feb 12;644:112-121

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Qingre Huazhuo Jiangsuan Decoction promotes autophagy by inhibiting PI3K/AKT/mTOR signaling pathway to relieve acute gouty arthritis.

Liu P, Xu Y, Ye J, Tan J, Hou J, Wang Y, Li J, Cui W, Wang S, Zhao Q
Journal of ethnopharmacology 2023 Feb 10;302(Pt A):115875

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Macrophage Migration Inhibitory Factor Promotes Expression of Matrix Metalloproteinases 1 and 3 in Spinal Cord Astrocytes following Gecko Tail Amputation.

Zhang H, Sun C, He B, Zhang X, Hao H, Hou Y, Li A, Wang Y, Wang Y
Journal of integrative neuroscience 2023 Feb 10;22(2):29

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Melanin-like polydopamine nanoparticles mediating anti-inflammatory and rescuing synaptic loss for inflammatory depression therapy.

Zhu TT, Wang H, Gu HW, Ju LS, Wu XM, Pan WT, Zhao MM, Yang JJ, Liu PM
Journal of nanobiotechnology 2023 Feb 10;21(1):52

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mTOR inhibitor, gemcitabine and PD-L1 antibody blockade combination therapy suppresses pancreatic cancer progression via metabolic reprogramming and immune microenvironment remodeling in Trp53(flox/+)LSL-Kras(G12D/+)Pdx-1-Cre murine models.

Qiu J, Feng M, Yang G, Cao Z, Liu Y, You L, Zhang T
Cancer letters 2023 Feb 1;554:216020

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GRAMD1/ASTER-mediated cholesterol transport promotes Smoothened cholesterylation at the endoplasmic reticulum.

Qiu ZP, Lin ZC, Hu A, Liu YB, Zeng WE, Zhao X, Shi XJ, Luo J, Song BL
The EMBO journal 2023 Feb 1;42(3):e111513

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HERC2 promotes inflammation-driven cancer stemness and immune evasion in hepatocellular carcinoma by activating STAT3 pathway.

Liu Y, Xu Q, Deng F, Zheng Z, Luo J, Wang P, Zhou J, Lu X, Zhang L, Chen Z, Zhang Q, Chen Q, Zuo D
Journal of experimental & clinical cancer research : CR 2023 Feb 1;42(1):38

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Clinical Implications of a New DDX58 Pathogenic Variant That Causes Lupus Nephritis due to RIG-I Hyperactivation.

Peng J, Wang Y, Han X, Zhang C, Chen X, Jin Y, Yang Z, An Y, Zhang J, Liu Z, Chen Y, Gao E, Zhang Y, Xu F, Zheng C, Zhou Q, Liu Z
Journal of the American Society of Nephrology : JASN 2023 Feb 1;34(2):258-272

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Molecular weight-dependent hyaluronic acid permeability and tight junction modulation in human buccal TR146 cell monolayers.

Park HY, Kweon DK, Kim JK
International journal of biological macromolecules 2023 Feb 1;227:182-192

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BMF-AS1/BMF Promotes Diabetic Vascular Calcification and Aging both In Vitro and In Vivo.

Lin X, Xiang QY, Li S, Song WL, Wang YJ, Ni YQ, Zhao Y, Li C, Wang Y, Li HH, Liang Z, Zhan JK, Liu YS
Aging and disease 2023 Feb 1;14(1):170-183

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The effect and mechanism of Huangqin-Baishao herb pair in the treatment of dextran sulfate sodium-induced ulcerative colitis.

Duan B, Hu Q, Ding F, Huang F, Wang W, Yin N, Liu Z, Zhang S, He D, Lu Q
Heliyon 2023 Dec;9(12):e23082

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MiR-224-5p inhibits osteoblast differentiation and impairs bone formation by targeting Runx2 and Sp7.

Ding S, Ma Y, Yang J, Tang Y, Jin Y, Li L, Ma C
Cytotechnology 2023 Dec;75(6):505-516

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Phenylalanine diminishes M1 macrophage inflammation.

Zhang Q, Chen S, Guo Y, He F, Fu J, Ren W
Science China. Life sciences 2023 Dec;66(12):2862-2876

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JSI-124 inhibits cell proliferation and tumor growth by inducing autophagy and apoptosis in murine malignant mesothelioma.

Zhang C, Sun Q, Zhao J, Jiang N, Hao Y, Luo J, Karim S, Wu L, de Perrot M, Peng C, Zhao X
Molecular carcinogenesis 2023 Dec;62(12):1888-1901

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Guilu-Erxian-Glue alleviates Tripterygium wilfordii polyglycoside-induced oligoasthenospermia in rats by resisting ferroptosis via the Keap1/Nrf2/GPX4 signaling pathway.

Ding J, Lu B, Liu L, Zhong Z, Wang N, Li B, Sheng W, He Q
Pharmaceutical biology 2023 Dec;61(1):213-227

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Integrating network pharmacology and experimental validation to decipher the mechanism of the Chinese herbal prescription modified Shen-Yan-Fang-Shuai formula in treating diabetic nephropathy.

Yu B, Zhou M, Dong Z, Zheng H, Zhao Y, Zhou J, Zhang C, Wei F, Yu G, Liu WJ, Liu H, Wang Y
Pharmaceutical biology 2023 Dec;61(1):1222-1233

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Transcriptomic analysis reveals the regulatory mechanism underlying the indirubin-mediated amelioration of dextran sulfate sodium-induced colitis in mice.

Liu Z, Zhang JR, Huang YX, Li XY, Zhu HP, Yang RY, Chen S
Pharmaceutical biology 2023 Dec;61(1):1082-1093

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NDRG1 promotes endothelial dysfunction and hypoxia-induced pulmonary hypertension by targeting TAF15.

Li C, Lv J, Wumaier G, Zhao Y, Dong L, Zeng Y, Zhu N, Zhang X, Wang J, Xia J, Li S
Precision clinical medicine 2023 Dec;6(4):pbad024

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Glioblastoma cellular MAP4K1 facilitates tumor growth and disrupts T effector cell infiltration.

Sun JM, Fan HY, Zhu Y, Pan TT, Wu YP, Zhang DY, Hou XY
Life science alliance 2023 Dec;6(12)

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Hypoxia dissociates HDAC6/FOXO1 complex and aggregates them into nucleus to regulate autophagy and osteogenic differentiation.

Xu Y, Wang Y, Xiao H, Li Y
Journal of periodontal research 2023 Dec;58(6):1248-1260

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Role of GPX4 inhibition-mediated ferroptosis in the chemoresistance of ovarian cancer to Taxol in vitro.

Feng Q, Hao S, Fang P, Zhang P, Sheng X
Molecular biology reports 2023 Dec;50(12):10189-10198

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TRPV4-mediated Ca(2+) deregulation causes mitochondrial dysfunction via the AKT/α-synuclein pathway in dopaminergic neurons.

Sun X, Kong J, Dong S, Kato H, Sato H, Hirofuji Y, Ito Y, Wang L, Kato TA, Torio M, Sakai Y, Ohga S, Fukumoto S, Masuda K
FASEB bioAdvances 2023 Dec;5(12):507-520

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Targeting TRIM24 promotes neuroblastoma differentiation and decreases tumorigenicity via LSD1/CoREST complex.

Shi Q, Yu B, Zhang Y, Yang Y, Xu C, Zhang M, Chen G, Luo F, Sun B, Yang R, Li Y, Feng H
Cellular oncology (Dordrecht, Netherlands) 2023 Dec;46(6):1763-1775

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LncRNA H19-EZH2 interaction promotes liver fibrosis via reprogramming H3K27me3 profiles.

Li XJ, Zhou F, Li YJ, Xue XY, Qu JR, Fan GF, Liu J, Sun R, Wu JZ, Zheng Q, Liu RP
Acta pharmacologica Sinica 2023 Dec;44(12):2479-2491

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Dual network analysis of transcriptome data for discovery of new therapeutic targets in non-small cell lung cancer.

Bai Y, Zhou L, Zhang C, Guo M, Xia L, Tang Z, Liu Y, Deng S
Oncogene 2023 Dec;42(49):3605-3618

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Integrating network pharmacology and experimental models to examine the mechanisms of corosolic acid in preventing hepatocellular carcinoma progression through activation PERK-eIF2a-ATF4 signaling.

Tang F, Peng Y, Liu J, Gao W, Xu Y
Naunyn-Schmiedeberg's archives of pharmacology 2023 Dec;396(12):3671-3682

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Hyperhomocysteinemia lowers serum testosterone concentration via impairing testosterone production in Leydig cells.

Su Z, Liu Z, Lei W, Xia K, Xiao A, Hu Z, Zhou M, Zhu F, Tian J, Yang M, Wang D, Xiang AP, Nie J
Cell biology and toxicology 2023 Dec;39(6):3077-3100

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Design, synthesis, and evaluation of novel benzoylhydrazone derivatives as Nur77 modulators with potent antitumor activity against hepatocellular carcinoma.

He F, Chen J, Zhao T, Wu Q, Yin N, Wang X, Zhong Y, Guo X, Qiu Y, Li B, Fang M, Wu Z
Journal of enzyme inhibition and medicinal chemistry 2023 Dec;38(1):2227777

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Molecular mechanisms in the miR-33a/LPPR4 pathway regulating unsaturated fatty acid synthesis in bovine mammary epithelial cells.

Wu Y, Zhang W, Wang Y, Lu Q, Zhou J, Chen Z, Yang Z, Loor JJ
Animal biotechnology 2023 Dec;34(7):2636-2648

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Mannose antagonizes GSDME-mediated pyroptosis through AMPK activated by metabolite GlcNAc-6P.

Ai YL, Wang WJ, Liu FJ, Fang W, Chen HZ, Wu LZ, Hong X, Zhu Y, Zhang CX, Liu LY, Hong WB, Zhou B, Chen QT, Wu Q
Cell research 2023 Dec;33(12):904-922

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Functional analysis of two SLC9A6 frameshift variants in lymphoblastoid cells from patients with Christianson syndrome.

He H, Zhang H, Chen H, He F, Yin F, Stauber T, Zou X, Peng J
CNS neuroscience & therapeutics 2023 Dec;29(12):4059-4069

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Photobiomodulation reduces neuropathic pain after spinal cord injury by downregulating CXCL10 expression.

Zhang Z, Zhu Z, Zuo X, Wang X, Ju C, Liang Z, Li K, Zhang J, Luo L, Ma Y, Song Z, Li X, Li P, Quan H, Huang P, Yao Z, Yang N, Zhou J, Kou Z, Chen B, Ding T, Wang Z, Hu X
CNS neuroscience & therapeutics 2023 Dec;29(12):3995-4017

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PP2Ac knockdown attenuates lipotoxicity‑induced pancreatic β‑cell dysfunction and apoptosis.

Zhang Z, Tong B, Liu J, Feng J, Song L, Wang H, Ke M, Xu C, Xu Y
Experimental and therapeutic medicine 2023 Dec;26(6):549

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FAM107A as a tumor suppressor in esophageal squamous carcinoma inhibits growth and metastasis.

Zhang J, Di S, Li M, Dong Y, Xie S, Gong T, Hu P, Jia Q, Fan B
Pathology, research and practice 2023 Dec;252:154945

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Blue light photobiomodulation induced apoptosis by increasing ROS level and regulating SOCS3 and PTEN/PI3K/AKT pathway in osteosarcoma cells.

Yang J, Jiang H, Fu Q, Qin H, Li Y, Liu M
Journal of photochemistry and photobiology. B, Biology 2023 Dec;249:112814

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Insulin-like growth factor 2 mRNA-binding protein 2 is a therapeutic target in ovarian cancer.

Yuan J, Li X, Wang F, Liu H, Guan W, Xu G
Experimental biology and medicine (Maywood, N.J.) 2023 Dec;248(23):2198-2209

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Integrated analysis of murine cornea identifies JAK/STAT signaling pathway upregulated specifically in female Vitamin A Deficient mice.

Yu H, Wu J, Li K, Huang Y, Wu T, Wang L, Huang Y
Experimental eye research 2023 Dec;237:109714

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HD-sEVs in bovine follicular fluid regulate granulosa cell apoptosis and estradiol secretion through the autophagy pathway.

Wang Y, Zhao Y, Ling Z, Luan D, Kang J, Dong X, Quan F
Theriogenology 2023 Dec;212:91-103

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Integrated NLRP3, AIM2, NLRC4, Pyrin inflammasome activation and assembly drive PANoptosis.

Oh S, Lee J, Oh J, Yu G, Ryu H, Kim D, Lee S
Cellular & molecular immunology 2023 Dec;20(12):1513-1526

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Inhibition of USP1 ameliorates hypertensive nephropathy through regulating oxidative stress and ferroptosis: A precise treatment via SJB3-019A nanodelivery.

Hao F, Li Y, Zhang Y, Han Y, Shang J, Gan L, Zheng J, Zhang C
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2023 Dec;193:187-197

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ENO1 promotes liver carcinogenesis through YAP1-dependent arachidonic acid metabolism.

Sun L, Suo C, Zhang T, Shen S, Gu X, Qiu S, Zhang P, Wei H, Ma W, Yan R, Chen R, Jia W, Cao J, Zhang H, Gao P
Nature chemical biology 2023 Dec;19(12):1492-1503

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Scribble promotes fibrosis-dependent mechanisms of hepatocarcinogenesis by p53/PUMA-mediated glycolysis.

Wu Y, Song L, Kong J, Wen Q, Jiao J, Wang X, Li G, Xu X, Zhan L
Biochimica et biophysica acta. Molecular basis of disease 2023 Dec;1869(8):166823

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Ceftazidime reduces cellular Skp2 to promote type-I interferon activity.

Qiao C, Huang F, He J, Wu Q, Zheng Z, Zhang T, Miao Y, Yuan Y, Chen X, Du Q, Xu Y, Wu D, Yu Z, Zheng H
Immunology 2023 Dec;170(4):527-539

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CBX4 promotes antitumor immunity by suppressing Pdcd1 expression in T cells.

Ren L, Li Z, Zhou Y, Zhang J, Zhao Z, Wu Z, Zhao Y, Ju Y, Pang X, Sun X, Wang W, Zhang Y
Molecular oncology 2023 Dec;17(12):2694-2708

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The synthetic oleanane triterpenoid CDDO-2P-Im binds GRP78/BiP to induce unfolded protein response-mediated apoptosis in myeloma.

Luo G, Aldridge K, Chen T, Aslot V, Kim BG, Han EH, Singh N, Li S, Xiao TS, Sporn MB, Letterio JJ
Molecular oncology 2023 Dec;17(12):2526-2545

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Trigonelline inhibits tubular epithelial-mesenchymal transformation in diabetic kidney disease via targeting Smad7.

Gong M, Guo Y, Dong H, Wu W, Wu F, Lu F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115747

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Cell-in-Cell-Mediated Entosis Reveals a Progressive Mechanism in Pancreatic Cancer.

Song J, Xu R, Zhang H, Xue X, Ruze R, Chen Y, Yin X, Wang C, Zhao Y
Gastroenterology 2023 Dec;165(6):1505-1521.e20

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Propionate promotes gluconeogenesis by regulating mechanistic target of rapamycin (mTOR) pathway in calf hepatocytes.

Wang GY, Qin SL, Zheng YN, Geng HJ, Chen L, Yao JH, Deng L
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2023 Dec;15:88-98

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The expression of Nramp1 modulates the uptake of Mycobacterium tuberculosis by macrophages through alternating inflammatory responses.

Meng C, Chen G, Wen D, Dong L, Cui X, Jing X, Cui J, Gao Y, Liu Y, Bu H, Wu C
Tuberculosis (Edinburgh, Scotland) 2023 Dec;143:102414

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Staphylococcus aureus planktonic but not biofilm environment induces an IFN-β macrophage immune response via the STING/IRF3 pathway.

Seebach E, Sonnenmoser G, Kubatzky KF
Virulence 2023 Dec;14(1):2254599

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Oligomeric Aβ25-35 induces the tyrosine phosphorylation of PSD-95 by SrcPTKs in rat hippocampal CA1 subfield.

Wu GM, Du CP, Xu Y
The International journal of neuroscience 2023 Dec;133(8):888-895

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Berberine ameliorates renal interstitial inflammation and fibrosis in mice with unilateral ureteral obstruction.

Tan E, Gao Z, Wang Q, Han B, Shi H, Wang L, Zhu G, Hou Y
Basic & clinical pharmacology & toxicology 2023 Dec;133(6):757-769

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The novel CDK9 inhibitor, XPW1, alone and in combination with BRD4 inhibitor JQ1, for the treatment of clear cell renal cell carcinoma.

Kuang Z, Guo K, Cao Y, Jiang M, Wang C, Wu Q, Hu G, Ao M, Huang M, Qin J, Zhao T, Lu S, Sun C, Li M, Wu T, Liu W, Fang M
British journal of cancer 2023 Dec;129(12):1915-1929

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Assessment of intestinal status in MPL(W515L) mutant myeloproliferative neoplasms mice model.

Zhu S, Xu K, Li S, Yu X, Liu Y, Zhang Q, Zeng L, Xu K, Fu C
International immunopharmacology 2023 Dec;125(Pt A):111091

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Lead and cadmium co-exposure modified PC12 viability and ER stress: study from a 3 × 3 factorial design.

Su X, Wang R, Wu Y, Yang M, Ba Y, Huang H
Toxicology research 2023 Dec;12(6):1135-1142

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Identification of TMEM53 as a novel SADS-CoV restriction factor that targets viral RNA-dependent RNA polymerase.

Yao YL, Luo Y, Wang Q, Geng R, Chen Y, Liu MQ, Li B, Chen J, Wu CG, Jia JK, Luo JY, He YT, Jiang TT, Zhu Y, Hu B, Zhou P, Shi ZL
Emerging microbes & infections 2023 Dec;12(2):2249120

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SARS-CoV-2 Omicron subvariants exhibit distinct fusogenicity, but similar sensitivity, to pan-CoV fusion inhibitors.

Xia S, Wang L, Jiao F, Yu X, Xu W, Huang Z, Li X, Wang Q, Zhu Y, Man Q, Jiang S, Lu L
Emerging microbes & infections 2023 Dec;12(1):2178241

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NSUN2-mediated M(5)c methylation of IRF3 mRNA negatively regulates type I interferon responses during various viral infections.

Wang H, Feng J, Zeng C, Liu J, Fu Z, Wang D, Wang Y, Zhang L, Li J, Jiang A, He M, Cao Y, Yan K, Tang H, Guo D, Xu K, Zhou X, Zhou L, Lan K, Zhou Y, Chen Y
Emerging microbes & infections 2023 Dec;12(1):2178238

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PROS1, a clinical prognostic biomarker and tumor suppressor, is associated with immune cell infiltration in breast cancer: A bioinformatics analysis combined with experimental verification.

He T, Sun X, Wu C, Yao L, Zhang Y, Liu S, Jiang Y, Li Y, Wang M, Xu Y
Cellular signalling 2023 Dec;112:110918

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Umbelliferone attenuates cisplatin-induced acute kidney injury by inhibiting oxidative stress and inflammation via NRF2.

Yang Z, Ning R, Liu Q, Zang R, Liu S, Sun S
Physiological reports 2023 Dec;11(23):e15879

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Inducible nitric oxide synthase accelerates nonalcoholic fatty liver disease progression by regulating macrophage autophagy.

Jin G, Yao X, Liu D, Zhang J, Zhang X, Yang Y, Bi Y, Zhang H, Dong G, Tang H, Cheng S, Hong F, Si M
Immunity, inflammation and disease 2023 Dec;11(12):e1114

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Inhibition of inflammation and infiltration of M2 macrophages in NSCLC through the ATF3/CSF1 axis: Role of miR-27a-3p.

Zhou B, Xu Y, Xu L, Kong Y, Li K, Chen B, Li J
International journal of experimental pathology 2023 Dec;104(6):292-303

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Probiotic-fermented Qushi decoction alleviates reserpine-induced spleen deficiency syndrome by regulating spleen function and gut microbiota dysbiosis.

Zeng W, Chen Y, Zhang H, Peng L, Li Y, Liu B, Liang H, Du B, Li P
Journal of the science of food and agriculture 2023 Dec;103(15):7702-7711

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Bone Marrow-Derived GCA(+) Immune Cells Drive Alzheimer's Disease Progression.

Zhou R, Wang L, Chen L, Feng X, Zhou R, Xiang P, Wen J, Huang Y, Zhou H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(36):e2303402

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Bone Marrow Stromal Cells inhibited the growth and metastasis of human U87 cells through delivering exosomal miR-506.

Zhang L, Ding Y, Zhou W, Xu X, Zheng J
Medicine 2023 Dec 8;102(49):e36582

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Prolonged sleep deprivation induces a cytokine-storm-like syndrome in mammals.

Sang D, Lin K, Yang Y, Ran G, Li B, Chen C, Li Q, Ma Y, Lu L, Cui XY, Liu Z, Lv SQ, Luo M, Liu Q, Li Y, Zhang EE
Cell 2023 Dec 7;186(25):5500-5516.e21

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The Human Placental Amniotic Membrane Mesenchymal-Stromal-Cell-Derived Conditioned Medium Inhibits Growth and Promotes Apoptosis of Human Cholangiocarcinoma Cells In Vitro and In Vivo by Suppressing IL-6/JAK2/STAT3 Signaling.

Jantalika T, Manochantr S, Kheolamai P, Tantikanlayaporn D, Thongsepee N, Warnnissorn N, Saijuntha W, Pinlaor S, Tantrawatpan C
Cells 2023 Dec 7;12(24)

---

HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance.

Ling H, Li Y, Peng C, Yang S, Seto E
bioRxiv : the preprint server for biology 2023 Dec 7;

---

The Role of Cellular Senescence in Cyclophosphamide-Induced Primary Ovarian Insufficiency.

Xu Z, Takahashi N, Harada M, Kunitomi C, Kusamoto A, Koike H, Tanaka T, Sakaguchi N, Urata Y, Wada-Hiraike O, Hirota Y, Osuga Y
International journal of molecular sciences 2023 Dec 6;24(24)

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DHA and EPA Alleviate Epileptic Depression in PTZ-Treated Young Mice Model by Inhibiting Neuroinflammation through Regulating Microglial M2 Polarization and Improving Mitochondrial Metabolism.

Yang Y, Chen L, Zhang N, Zhao Y, Che H, Wang Y, Zhang T, Wen M
Antioxidants (Basel, Switzerland) 2023 Dec 6;12(12)

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Study on the mechanism of Orthosiphon aristatus (Blume) Miq. in the treatment of hyperuricemia by microbiome combined with metabonomics.

Zhu C, Niu H, Bian M, Zhang X, Zhang X, Zhou Z
Journal of ethnopharmacology 2023 Dec 5;317:116805

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Pro-inflammatory Cytokines Promote the Occurrence and Development of Colitis-associated Colorectal Cancer by Inhibiting miR-615-5p.

Sun D, Gong L, Wang X, Chen S, Yi J, Liu X
Inflammatory bowel diseases 2023 Dec 5;29(12):1854-1864

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Design, synthesis, and biological evaluation of novel 4,4'-bipyridine derivatives acting as CDK9-Cyclin T1 protein-protein interaction inhibitors against triple-negative breast cancer.

Gao G, Li J, Cao Y, Li X, Qian Y, Wang X, Li M, Qiu Y, Wu T, Wang L, Fang M
European journal of medicinal chemistry 2023 Dec 5;261:115858

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Mechanistic insights into the homo-dimerization of HOIL-1L and SHARPIN.

Zhang Y, Xu X, Wang Y, Wang Y, Zhou X, Pan L
Biochemical and biophysical research communications 2023 Dec 31;689:149239

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Super-enhancer-associated EEPD1 facilitates EMT-mediated metastasis by regulating the PI3K/AKT/mTOR pathway in gastric cancer.

Jin Y, Xia Y, Du H, Xiang T, Lan B, Wei S, Li H, Huang H
Biochemical and biophysical research communications 2023 Dec 31;689:149188

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Soyasaponin I alleviates hypertensive intracerebral hemorrhage by inhibiting the renin-angiotensin-aldosterone system.

Li W, Li SG, Li L, Yang LJ, Li ZS, Li X, Ye AY, Xiong Y, Zhang Y, Xiong YY
Clinical and experimental hypertension (New York, N.Y. : 1993) 2023 Dec 31;45(1):2177667

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Exopolysaccharide from Weissella confusa J4-1 inhibits colorectal cancer via induction of cell cycle arrest.

Liu L, Du Y, Du Y, Yan W, Li Y, Cui K, Li Z, Yu P, Zhang W, Feng J, Ma W, Zhao H
International journal of biological macromolecules 2023 Dec 31;253(Pt 8):127625

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An injectable and light curable hyaluronic acid composite gel with anti-biofilm, anti-inflammatory and pro-healing characteristics for accelerating infected wound healing.

Lin X, Fu T, Lei Y, Xu J, Wang S, He F, Xie Z, Zhang L
International journal of biological macromolecules 2023 Dec 31;253(Pt 5):127190

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Astragaloside IV enhances the sensitivity of breast cancer stem cells to paclitaxel by inhibiting stemness.

Huang P, Li H, Ren L, Xie H, Chen L, Liang Y, Hu Y, Selistre-de-Araujo HS, Boussios S, Jhawar SR, Cui R, Zuo Q, Chen Q
Translational cancer research 2023 Dec 31;12(12):3703-3717

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IGF2BP1 enhances the stability of SIK2 mRNA through m(6)A modification to promote non-small cell lung cancer progression.

Xu Y, Xu L, Kong Y, Li K, Li J, Xu F, Liang S, Chen B
Biochemical and biophysical research communications 2023 Dec 3;684:149113

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Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy.

Cheng J, Yan Z, Jiang K, Liu C, Xu D, Lyu X, Hu X, Zhang S, Zhou Y, Li J, Zhao Y
Journal of medicinal chemistry 2023 Dec 28;66(24):16991-17025

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RTKN2 knockdown alleviates the malignancy of breast cancer cells by regulating the Wnt/β-catenin pathway.

Zhang X, Wang J, Li H
Scientific reports 2023 Dec 27;13(1):23023

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DPP4 Regulates the Th17/IL-17 Axis and Accelerates Epithelial Mesenchymal Transition to Promote Ovalbumin-Induced Asthma in Female C57BL/6J Mice.

Li L, Ling F, Li R, Jiang Y, Long H, Xiao B, Wu J, Long Z, Ma L
Frontiers in bioscience (Landmark edition) 2023 Dec 26;28(12):342

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Biochemical Toxicological Study of Insulin Overdose in Rats: A Forensic Perspective.

Bian C, He X, Wang Q, Zheng Z, Zhang Y, Xiong H, Li Y, Zhao M, Li J
Toxics 2023 Dec 23;12(1)

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Circulating small extracellular vesicles microRNAs plus CA-125 for treatment stratification in advanced ovarian cancer.

Zhou X, Liu M, Sun L, Cao Y, Tan S, Luo G, Liu T, Yao Y, Xiao W, Wan Z, Tang J
Journal of translational medicine 2023 Dec 22;21(1):927

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Phosphorylated Adapter RNA Export Protein Is Methylated at Lys 381 by an Methyltransferase-like 21C (METTL21C).

Ke M, Yu X, Sun Y, Han S, Wang L, Zhang T, Zeng W, Lu H
International journal of molecular sciences 2023 Dec 21;25(1)

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Schistosome egg-derived extracellular vesicles deliver Sja-miR-71a inhibits host macrophage and neutrophil extracellular traps via targeting Sema4D.

Liao Y, Zhu Z, Liu Y, Wu J, Li D, Li Z, Xu J, Yang R, Wang L
Cell communication and signaling : CCS 2023 Dec 21;21(1):366

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Choroid plexus mast cells drive tumor-associated hydrocephalus.

Li Y, Di C, Song S, Zhang Y, Lu Y, Liao J, Lei B, Zhong J, Guo K, Zhang N, Su S
Cell 2023 Dec 21;186(26):5719-5738.e28

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Identification and validation of key biomarkers associated with macrophages in nonalcoholic fatty liver disease based on hdWGCNA and machine learning.

Li R, Zhao M, Miao C, Shi X, Lu J
Aging 2023 Dec 21;15(24):15451-15472

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BACH1 controls hepatic insulin signaling and glucose homeostasis in mice.

Jin J, He Y, Guo J, Pan Q, Wei X, Xu C, Qi Z, Li Q, Ma S, Lin J, Jiang N, Ma J, Wang X, Jiang L, Ding Q, Osto E, Zhi X, Meng D
Nature communications 2023 Dec 21;14(1):8428

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Nobiletin Ameliorates Hepatic Lipid Deposition, Oxidative Stress, and Inflammation by Mechanisms That Involve the Nrf2/NF-κB Axis in Nonalcoholic Fatty Liver Disease.

Fan C, Ling-Hu A, Sun D, Gao W, Zhang C, Duan X, Li H, Tian W, Yu Q, Ke Z
Journal of agricultural and food chemistry 2023 Dec 20;71(50):20105-20117

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Vidofludimus inhibits porcine reproductive and respiratory syndrome virus infection by targeting dihydroorotate dehydrogenase.

Yang Y, Gao Y, Zhang L, Liu X, Sun Y, Bai J, Jiang P
Veterinary research 2023 Dec 20;54(1):124

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Hedgehog-Gli1-derived exosomal circ-0011536 mediates peripheral neural remodeling in pancreatic cancer by modulating the miR-451a/VGF axis.

Dai W, Wu X, Li J, Tang W, Wang Y, Xu W, Han D, Xu X, Xu X
Journal of experimental & clinical cancer research : CR 2023 Dec 2;42(1):329

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Insights into the ISG15 transfer cascade by the UBE1L activating enzyme.

Wallace I, Baek K, Prabu JR, Vollrath R, von Gronau S, Schulman BA, Swatek KN
Nature communications 2023 Dec 2;14(1):7970

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The nonstructural protein 1 of respiratory syncytial virus hijacks host mitophagy as a novel mitophagy receptor to evade the type I IFN response in HEp-2 cells.

Cheng J, Wang Y, Yin L, Liang W, Zhang J, Ma C, Zhang Y, Liu B, Wang J, Zhao W, Li M, Wei L
mBio 2023 Dec 19;14(6):e0148023

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Gss deficiency causes age-related fertility impairment via ROS-triggered ferroptosis in the testes of mice.

Zhu H, Cheng Y, Wang X, Yang X, Liu M, Liu J, Liu S, Wang H, Zhang A, Li R, Ye C, Zhang J, Gao J, Fu X, Wu B
Cell death & disease 2023 Dec 19;14(12):845

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ER Stress-Perturbed Intracellular Protein O-GlcNAcylation Aggravates Podocyte Injury in Diabetes Nephropathy.

Song S, Hu T, Shi X, Jin Y, Liu S, Li X, Zou W, Wang C
International journal of molecular sciences 2023 Dec 18;24(24)

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The HSP40 family chaperone isoform DNAJB6b prevents neuronal cells from tau aggregation.

Chang YL, Yang CC, Huang YY, Chen YA, Yang CW, Liao CY, Li H, Wu CS, Lin CH, Teng SC
BMC biology 2023 Dec 18;21(1):293

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Fluorinated Cell-Penetrating Peptide for Co-Delivering siHIF-1α and Sorafenib to Enhance In Vitro Anti-Tumor Efficacy.

Wan Y, Yang Y, Lai Q, Wang W, Wu M, Feng S
Pharmaceutics 2023 Dec 16;15(12)

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Glycyrrhetinic acid attenuates endoplasmic reticulum stress-induced hepatocyte apoptosis via CHOP/DR5/Caspase 8 pathway in cholestasis.

Zou B, Zhang S, Zhao J, Song G, Weng F, Xu X, Li F, Jin J, Yan D, Huang K, Liu C, Li Y, Qiu F
European journal of pharmacology 2023 Dec 15;961:176193

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GPR146 regulates pulmonary vascular remodeling by promoting pulmonary artery smooth muscle cell proliferation through 5-lipoxygenase.

Huang J, Xie Y, Chen B, Xia Y, Jiang Y, Sun Z, Liu Y
European journal of pharmacology 2023 Dec 15;961:176123

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Glutathione-responsive PROTAC for targeted degradation of ERα in breast cancer cells.

Zhou Z, Fan H, Yu D, Shi F, Li Q, Zhang Z, Wang X, Zhang X, Dong C, Sun H, Mi W
Bioorganic & medicinal chemistry 2023 Dec 15;96:117526

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Targeting AKT induced Ferroptosis through FTO/YTHDF2-dependent GPX4 m6A methylation up-regulating and degradating in colorectal cancer.

Zhang G, Mi W, Wang C, Li J, Zhang Y, Liu N, Jiang M, Jia G, Wang F, Yang G, Zhang L, Wang J, Fu Y, Zhang Y
Cell death discovery 2023 Dec 15;9(1):457

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Adoptive transfer of immature dendritic cells with high HO-1 expression delays the onset of T1DM in NOD mice.

Yang X, Ma Z, Tan X, Shi Y, Yuan M, Chen G, Luo X, Hou L
Life sciences 2023 Dec 15;335:122273

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A Study on the Pharmacological Effects and Mechanism of Rhodojaponin III in Rheumatoid Arthritis.

Liu X, Li S, Xu Y, Mei W, Zhou R
Frontiers in bioscience (Landmark edition) 2023 Dec 15;28(12):337

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Identification of ANXA3 as a biomarker associated with pyroptosis in ischemic stroke.

Liu L, Cai Y, Deng C
European journal of medical research 2023 Dec 15;28(1):596

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Autophagy is involved in degradation of AQP1 in response to an acute decrement in tonicity.

Guo X, Xu L, Kong Y, Li M, Zhai Q, Liang B, Zhao X, Long L, Huang M, Wang W, Li C
iScience 2023 Dec 15;26(12):108485

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Foxp3-mediated blockage of ryanodine receptor 2 underlies contact-based suppression by regulatory T cells.

Wang X, Geng S, Meng J, Kang N, Liu X, Xu Y, Lyu H, Xu Y, Xu X, Song X, Zhang B, Wang X, Nuerbulati N, Zhang Z, Zhai D, Mao X, Sun R, Wang X, Wang R, Guo J, Chen SRW, Zhou X, Xia T, Qi H, Hu X, Shi Y
The Journal of clinical investigation 2023 Dec 15;133(24)

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IL20RB signaling enhances stemness and chemotherapy resistance in pancreatic cancer.

Li XH, Huang GZ, Xu ZL, Zhao CY, Dong XY, Cui BK, Lin XJ
Journal of translational medicine 2023 Dec 14;21(1):911

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Cyclosporine A alleviates colitis by inhibiting the formation of neutrophil extracellular traps via the regulating pentose phosphate pathway.

Xu C, Ye Z, Jiang W, Wang S, Zhang H
Molecular medicine (Cambridge, Mass.) 2023 Dec 13;29(1):169

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Alleviation of ischemia-reperfusion induced renal injury by chemically modified SOD2 mRNA delivered via lipid nanoparticles.

Hou Y, Lin S, Xia J, Zhang Y, Yin Y, Huang M, Xu Y, Yang W, Zhu Y
Molecular therapy. Nucleic acids 2023 Dec 12;34:102067

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Cytomegalovirus-vectored COVID-19 vaccines elicit neutralizing antibodies against the SARS-CoV-2 Omicron variant (BA.2) in mice.

Liu J, Jaijyan DK, Chen Y, Feng C, Yang S, Xu Z, Zhan N, Hong C, Li S, Cheng T, Zhu H
Microbiology spectrum 2023 Dec 12;11(6):e0246323

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NLRP3 inflammasome-mediated pyroptosis involvement in cadmium exposure-induced cognitive deficits via the Sirt3-mtROS axis.

Wang D, Wu Y, Sun S, Zhao P, Zhou X, Liang C, Ma Y, Li S, Zhu X, Hao X, Shi J, Fan H
The Science of the total environment 2023 Dec 10;903:166478

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Inhibition of the lncRNA 585189 prevents podocyte injury and mitochondria dysfunction by promoting hnRNP A1 and SIRT1 in diabetic nephropathy.

Chen H, Liu Y, Zhang T, Huang T, Lang Y, Sheng Q, Liu Y, Kong Z, Gao Y, Lu S, Yang M, Li X, Wang R, Lv Z
Molecular and cellular endocrinology 2023 Dec 1;578:112065

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Restoring System xc- activity by xCT overexpression inhibited neuronal ferroptosis and improved neurological deficits after experimental subarachnoid hemorrhage.

Cao C, Lu T, Cheng Q, Cui G, Wang Z, Li X, Li H, Gao H, Shen H, Sun Q
Brain research 2023 Dec 1;1820:148556

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CRISPR screening identifies the deubiquitylase ATXN3 as a PD-L1-positive regulator for tumor immune evasion.

Wang S, Iyer R, Han X, Wei J, Li N, Cheng Y, Zhou Y, Gao Q, Zhang L, Yan M, Sun Z, Fang D
The Journal of clinical investigation 2023 Dec 1;133(23)

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LY6E is a pan-coronavirus restriction factor in the respiratory tract.

Mar KB, Wells AI, Caballero Van Dyke MC, Lopez AH, Eitson JL, Fan W, Hanners NW, Evers BM, Shelton JM, Schoggins JW
Nature microbiology 2023 Aug;8(8):1587-1599

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Exosomal PPARγ derived from macrophages suppresses LPS-induced peritonitis by negative regulation of CD14/TLR4 axis.

Meng M, Lu M, Feng J, Zhou X, Meng P, Chen L, Zou X, Liu X, Liu L, Gao X, Zhang Y
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Aug;72(8):1567-1581

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Retrotransposons hijack alt-EJ for DNA replication and eccDNA biogenesis.

Yang F, Su W, Chung OW, Tracy L, Wang L, Ramsden DA, Zhang ZZZ
Nature 2023 Aug;620(7972):218-225

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Scutellarin Acts via MAPKs Pathway to Promote M2 Polarization of Microglial Cells.

Chen HL, Yang L, Zhang XL, Jia QY, Duan ZD, Li JJ, Zheng LY, Liu TT, Qi Z, Yuan Y, Wu CY
Molecular neurobiology 2023 Aug;60(8):4304-4323

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The therapeutic effect of tanshinone IIA in mouse astrocytes after treatment with Angiostrongylus cantonensis fifth-stage larval excretory-secretory products.

Chen KY, Chen YJ, Cheng CJ, Jhan KY, Chiu CH, Wang LC
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2023 Aug;56(4):853-862

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Aquaporin 1 is a prognostic marker and inhibits tumour progression through downregulation of Snail expression in intrahepatic cholangiocarcinoma.

Zhuang MQ, Jiang XL, Liu WD, Xie QH, Wang P, Dong LW, Hu HP, Zhou HB, Zhou YB
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2023 Aug;55(8):1133-1140

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The G allele of SNP rs3922 reduces the binding affinity between IGF2BP3 and CXCR5 correlating with a lower antibody production.

Duan Z, Ma L, Jin J, Ma L, Ye L, Wu J, Luo Y
European journal of immunology 2023 Aug;53(8):e2250261

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Dipyridamole enhances the anti-cancer ability of aspirin against colorectal cancer by inducing apoptosis in an unfolded protein response-dependent manner.

Huang S, Zhang NQ, Xu CJ, Huang WQ, Li DX, Li J, Yao LL, Sundquist K, Sundquist J, Jiang SH, Xing X, Hu LP, Zhang ZG, Ji J, Zhang XL
Cellular oncology (Dordrecht, Netherlands) 2023 Aug;46(4):953-967

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Glutamine metabolic microenvironment drives M2 macrophage polarization to mediate trastuzumab resistance in HER2-positive gastric cancer.

Hu X, Ma Z, Xu B, Li S, Yao Z, Liang B, Wang J, Liao W, Lin L, Wang C, Zheng S, Wu Q, Huang Q, Yu L, Wang F, Shi M
Cancer communications (London, England) 2023 Aug;43(8):909-937

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Reversal of the detrimental effects of social isolation on ischemic cerebral injury and stroke-associated pneumonia by inhibiting small intestinal γδ T-cell migration into the brain and lung.

Xie B, Zhang Y, Han M, Wang M, Yu Y, Chen X, Wu Y, Hashimoto K, Yuan S, Shang Y, Zhang J
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2023 Aug;43(8):1267-1284

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Cell Cycle-Related FAM64A Could be Activated by TGF-β Signaling to Promote Glioma Progression.

Fu M, Zhang J, Zhang L, Feng Y, Fang X, Zhang J, Wen W, Hua W, Mao Y
Cellular and molecular neurobiology 2023 Aug;43(6):2975-2987

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SARS-CoV-2 Nsp8 induces mitophagy by damaging mitochondria.

Zong S, Wu Y, Li W, You Q, Peng Q, Wang C, Wan P, Bai T, Ma Y, Sun B, Qiao J
Virologica Sinica 2023 Aug;38(4):520-530

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Dickkopf-1 promotes vascular smooth muscle cell foam cell formation and atherosclerosis development through CYP4A11/SREBP2/ABCA1.

Li X, Zheng T, Zhang Y, Zhao Y, Liu F, Dai S, Liu X, Zhang M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Aug;37(8):e23048

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Metal-ion transporter SLC39A8 is required for brain manganese uptake and accumulation.

Liu Q, Jenkitkasemwong S, Prami TA, McCabe SM, Zhao N, Hojyo S, Fukada T, Knutson MD
The Journal of biological chemistry 2023 Aug;299(8):105078

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PTBP1 suppresses porcine epidemic diarrhea virus replication via inducing protein degradation and IFN production.

Qin W, Kong N, Zhang Y, Wang C, Dong S, Zhai H, Zhai X, Yang X, Ye C, Ye M, Tong W, Liu C, Yu L, Zheng H, Yu H, Zhang W, Lan D, Tong G, Shan T
The Journal of biological chemistry 2023 Aug;299(8):104987

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HIV-1 subtype B Tat enhances NOTCH3 signaling in astrocytes to mediate oxidative stress, inflammatory response, and neuronal apoptosis.

Gao L, Sun W, Zhang D, Shang Y, Li L, Tao W, Zhang L, Liu H
Journal of neurovirology 2023 Aug;29(4):479-491

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Role of Escin in breast cancer therapy: potential mechanism for inducing ferroptosis and synergistic antitumor activity with cisplatin.

Li C, He Z, Yao F, Liao S, Sun K, Sun S, Li Z, Wang Z
Apoptosis : an international journal on programmed cell death 2023 Aug;28(7-8):1154-1167

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Identification and validation of SOCS1/2/3/4 as potential prognostic biomarkers and correlate with immune infiltration in glioblastoma.

Dai L, Han Y, Yang Z, Zeng Y, Liang W, Shi Z, Tao Y, Liang X, Liu W, Zhou S, Xing Z, Hu W, Wang X
Journal of cellular and molecular medicine 2023 Aug;27(15):2194-2214

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Overexpression of hepatic pescadillo 1 in obesity induces lipid dysregulation by inhibiting autophagy.

Zhou J, Lu Y, Lin Y, Li C, Liu J, Jiang Z, Chen K
Translational research : the journal of laboratory and clinical medicine 2023 Aug;258:1-15

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ETS1 Ameliorates Hyperoxia-Induced Bronchopulmonary Dysplasia in Mice by Activating Nrf2/HO-1 Mediated Ferroptosis.

Yang M, Chen Y, Huang X, Shen F, Meng Y
Lung 2023 Aug;201(4):425-441

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Profilin1 Regulates Trophoblast Invasion and Macrophage Differentiation.

Chen X, Song QL, Wang JY, Ji R, Li ZH, Cao ML, Mu XF, Guo DY, Zhang Y, Yang J
The American journal of pathology 2023 Aug;193(8):1059-1071

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Contrasting effects of filamin A and B proteins in modulating filovirus entry.

Shepley-McTaggart A, Liang J, Ding Y, Djurkovic MA, Kriachun V, Shtanko O, Sunyer O, Harty RN
PLoS pathogens 2023 Aug;19(8):e1011595

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N protein of PEDV plays chess game with host proteins by selective autophagy.

Zhai X, Kong N, Zhang Y, Song Y, Qin W, Yang X, Ye C, Ye M, Tong W, Liu C, Zheng H, Yu H, Zhang W, Yang X, Zhang G, Tong G, Shan T
Autophagy 2023 Aug;19(8):2338-2352

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Mesenchymal Stem Cell-Derived Exosomal miR-150-3p Affects Intracerebral Hemorrhage By Regulating TRAF6/NF-κB Axis, Gut Microbiota and Metabolism.

Sun J, Xu G
Stem cell reviews and reports 2023 Aug;19(6):1907-1921

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Death-associated protein kinase 1 is associated with cognitive dysfunction in major depressive disorder.

Li XH, Zhu HC, Cui XM, Wang W, Yang L, Wang LB, Hu NW, Duan DX
Neural regeneration research 2023 Aug;18(8):1795-1801

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Potential targets and mechanisms of photobiomodulation for spinal cord injury.

Ju C, Ma YG, Zuo XS, Wang XK, Song ZW, Zhang ZH, Zhu ZJ, Li X, Liang ZW, Ding T, Wang Z, Hu XY
Neural regeneration research 2023 Aug;18(8):1782-1788

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High SNRPA1 expression leads to poor prognosis in patients with lung adenocarcinoma.

Yang JJ, Yang YJ, Gu YL, Tong L, Liu YF, Zhang JG
The clinical respiratory journal 2023 Aug;17(8):719-732

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Schwann cell-derived amphiregulin enhances nerve regeneration via supporting the proliferation and migration of Schwann cells and the elongation of axons.

Chen S, Chen Q, Zhang X, Shen Y, Shi X, Dai X, Yi S
Journal of neurochemistry 2023 Aug;166(4):678-691

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1,8-Cineole ameliorates diabetic retinopathy by inhibiting retinal pigment epithelium ferroptosis via PPAR-γ/TXNIP pathways.

Liu Z, Gan S, Fu L, Xu Y, Wang S, Zhang G, Pan D, Tao L, Shen X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Aug;164:114978

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AF9 sustains glycolysis in colorectal cancer via H3K9ac-mediated PCK2 and FBP1 transcription.

He X, Zhong X, Fang Y, Hu Z, Chen Z, Wang Y, Huang H, Zhao S, Li D, Wei P
Clinical and translational medicine 2023 Aug;13(8):e1352

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PRSS2 regulates EMT and metastasis via MMP-9 in gastric cancer.

Wang F, Yi J, Chen Y, Bai X, Lu C, Feng S, Zhou X
Acta histochemica 2023 Aug;125(6):152071

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Ficolin A knockout alleviates sepsis-induced severe lung injury in mice by restoring gut Akkermansia to inhibit S100A4/STAT3 pathway.

Wu X, Xuan W, Yang X, Liu W, Zhang H, Jiang G, Cao B, Jiang Y
International immunopharmacology 2023 Aug;121:110548

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Astragaloside IV protects LO2 cells from oxidative damage caused by radiation-induced bystander effect through Akt/Nrf2 pathway.

Wan D, Zhu Z, Zhou J, Deng Z, Lei P, Liu Q, Sun X, Huang B
Toxicology research 2023 Aug;12(4):635-647

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ROS Scavenging Nanozyme Modulates Immunosuppression for Sensitized Cancer Immunotherapy.

Mo W, Liu S, Zhao X, Wei F, Li Y, Sheng X, Cao W, Ding M, Zhang W, Chen X, Meng L, Yao S, Diao W, Wei H, Guo H
Advanced healthcare materials 2023 Aug;12(21):e2300191

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Inhibition of VEGFR2 and EGFR signaling cooperatively suppresses the proliferation of oral squamous cell carcinoma.

Onda M, Ota A, Ito K, Ono T, Karnan S, Kato M, Kondo S, Furuhashi A, Hayashi T, Hosokawa Y, Kazaoka Y
Cancer medicine 2023 Aug;12(15):16416-16430

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YAP/STAT3 inhibited CD8(+) T cells activity in the breast cancer immune microenvironment by inducing M2 polarization of tumor-associated macrophages.

Wang C, Shen N, Guo Q, Tan X, He S
Cancer medicine 2023 Aug;12(15):16295-16309

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Angiopoietin-like 4 induces head and neck squamous cell carcinoma cell migration through the NRP1/ABL1/PXN pathway.

Hefni E, Menon D, Ma T, Asiedu EB, Sultan A, Meiller T, Schneider A, Sodhi A, Montaner S
Cellular signalling 2023 Aug;108:110697

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Curcumin enhances elvitegravir concentration and alleviates oxidative stress and inflammatory response.

Godse S, Zhou L, Sinha N, Kodidela S, Kumar A, Singh UP, Kumar S
Research square 2023 Aug 9;

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Mitochondrial carrier 1 (MTCH1) governs ferroptosis by triggering the FoxO1-GPX4 axis-mediated retrograde signaling in cervical cancer cells.

Wang X, Ji Y, Qi J, Zhou S, Wan S, Fan C, Gu Z, An P, Luo Y, Luo J
Cell death & disease 2023 Aug 8;14(8):508

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Hesperidin may improve depressive symptoms by binding NLRP3 and influencing the pyroptosis pathway in a rat model.

Cao H, Yang D, Nie K, Lin R, Peng L, Zhou X, Zhang M, Zeng Y, Liu L, Huang W
European journal of pharmacology 2023 Aug 5;952:175670

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SQLE promotes pancreatic cancer growth by attenuating ER stress and activating lipid rafts-regulated Src/PI3K/Akt signaling pathway.

Xu R, Song J, Ruze R, Chen Y, Yin X, Wang C, Zhao Y
Cell death & disease 2023 Aug 4;14(8):497

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Identification of NOX4 as a New Biomarker in Hepatocellular Carcinoma and Its Effect on Sorafenib Therapy.

Li HZ, Liu QQ, Chang DH, Li SX, Yang LT, Zhou P, Deng JB, Huang CH, Xiao YD
Biomedicines 2023 Aug 4;11(8)

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Ficolin B secreted by alveolar macrophage exosomes exacerbates bleomycin-induced lung injury via ferroptosis through the cGAS-STING signaling pathway.

Wu X, Jiang Y, Li R, Xia Y, Li F, Zhao M, Li G, Tan X
Cell death & disease 2023 Aug 30;14(8):577

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Tissue pleiotropic effect of biotin and prebiotic supplementation in established obesity.

Voland L, Yuan M, Lecoutre S, Debédat J, Pelloux V, Pradeau M, Coles E, Merabtene F, Zhang C, Mardinoglu A, Le Roy T, Soula H, Clément K
American journal of physiology. Endocrinology and metabolism 2023 Aug 30;

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Optimized allotopic expression of mitochondrial ND6 transgene restored complex I and apoptosis deficiencies caused by LHON-linked ND6 14484T > C mutation.

Wang J, Ji Y, Ai C, Chen JR, Gan D, Zhang J, Mo JQ, Guan MX
Journal of biomedical science 2023 Aug 3;30(1):63

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MicroRNA-144-3p protects against chemotherapy-induced apoptosis of ovarian granulosa cells and activation of primordial follicles by targeting MAP3K9.

Liu M, Xiao B, Zhu Y, Chen M, Huang J, Guo H, Wang F
European journal of medical research 2023 Aug 3;28(1):264

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MATR3-antisense LINE1 RNA meshwork scaffolds higher-order chromatin organization.

Zhang Y, Cao X, Gao Z, Ma X, Wang Q, Xu X, Cai X, Zhang Y, Zhang Z, Wei G, Wen B
EMBO reports 2023 Aug 3;24(8):e57550

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Hedgehog receptors exert immune-surveillance roles in the epidermis across species.

Wang Q, Fu R, Li G, Xiong S, Zhu Y, Zhang H
Cell reports 2023 Aug 29;42(8):112929

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SLC38A5 aggravates DC-mediated psoriasiform skin inflammation via potentiating lysosomal acidification.

Zhu L, Xia X, Li G, Zhu C, Li Q, Wang B, Shi NX, Lei Z, Yang S, Zhang Z, Li H, Tan J, Liu Z, Wen Q, Zhong H, Lin XJ, Sun G, Bao X, Wang Q, Deng L, Bin L, Cao G, Yin Z
Cell reports 2023 Aug 29;42(8):112910

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Sox10 escalates vascular inflammation by mediating vascular smooth muscle cell transdifferentiation and pyroptosis in neointimal hyperplasia.

Xu X, Zhang DD, Kong P, Gao YK, Huang XF, Song Y, Zhang WD, Guo RJ, Li CL, Chen BW, Sun Y, Zhao YB, Jia FY, Wang X, Zhang F, Han M
Cell reports 2023 Aug 29;42(8):112869

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A p53/LINC00324 positive feedback loop suppresses tumor growth by counteracting SET-mediated transcriptional repression.

Zhang L, Zhang J, Xuan X, Wu D, Yu J, Wang P, Yang X, Zhang J, Gan W, He M, Liu XM, Zhou J, Wang D, Gu W, Li D
Cell reports 2023 Aug 29;42(8):112833

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The non-redundant functions of PIWI family proteins in gametogenesis in golden hamsters.

Lv X, Xiao W, Lai Y, Zhang Z, Zhang H, Qiu C, Hou L, Chen Q, Wang D, Gao Y, Song Y, Shui X, Chen Q, Qin R, Liang S, Zeng W, Shi A, Li J, Wu L
Nature communications 2023 Aug 29;14(1):5267

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Inhibition of cancer-type amino acid transporter LAT1 suppresses B16-F10 melanoma metastasis in mouse models.

Shi Z, Kaneda-Nakashima K, Ohgaki R, Xu M, Okanishi H, Endou H, Nagamori S, Kanai Y
Scientific reports 2023 Aug 25;13(1):13943

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A Compared Study of Eicosapentaenoic Acid and Docosahexaenoic Acid in Improving Seizure-Induced Cognitive Deficiency in a Pentylenetetrazol-Kindling Young Mice Model.

Yang Y, Wang X, Chen L, Wang S, Han J, Wang Z, Wen M
Marine drugs 2023 Aug 24;21(9)

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Convergent activation of Ca(2+) permeability in two-pore channel 2 through distinct molecular routes.

Saito R, Mu Q, Yuan Y, Rubio-Alarcón M, Eznarriaga M, Zhao P, Gunaratne G, Kumar S, Keller M, Bracher F, Grimm C, Brailoiu E, Marchant JS, Rahman T, Patel S
Science signaling 2023 Aug 22;16(799):eadg0661

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Flt3 Activation Mitigates Mitochondrial Fragmentation and Heart Dysfunction through Rebalanced L-OPA1 Processing by Hindering the Interaction between Acetylated p53 and PHB2 in Cardiac Remodeling.

Zhang K, Zheng Y, Bao G, Ma W, Han B, Shi H, Zhao Z
Antioxidants (Basel, Switzerland) 2023 Aug 22;12(9)

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DpdtpA, A Multi-metal Ion Chelator, Attenuates Tau Phosphorylation and Microglial Inflammatory Response via Regulating the PI3K/AKT/GSK-3β Signal Pathways.

Wang L, Wei Y, Sun Z, Jiang LH, Yin Y, Zheng P, Fu Y, Wang H, Li C, Wang JZ
Neuroscience 2023 Aug 21;526:196-203

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Differential effects of PGAM5 knockout on high fat high fructose diet and methionine choline-deficient diet induced non-alcoholic steatohepatitis (NASH) in mice.

Li L, Guo C, Yu Y, Tie L, Lu G, Liu F, Han X, Ji L, Zou X
Cell & bioscience 2023 Aug 21;13(1):154

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[VDAC1 participates in house dust mite-induced asthmatic airway inflammation in mice by inducing ferroptosis of airway epithelial cells].

Huang Y, Lin L, Huang H, Dong H
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Aug 20;43(8):1333-1338

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Inosine enhances tumor mitochondrial respiration by inducing Rag GTPases and nascent protein synthesis under nutrient starvation.

Li MX, Wu XT, Jing WQ, Hou WK, Hu S, Yan W
Cell death & disease 2023 Aug 2;14(8):492

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Mutational burden of XPNPEP3 leads to defects in mitochondrial complex I and cilia in NPHPL1.

Tong L, Rao J, Yang C, Xu J, Lu Y, Zhang Y, Cang X, Xie S, Mao J, Jiang P
iScience 2023 Aug 18;26(8):107446

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IRP1 mediated ferroptosis reverses temozolomide resistance in glioblastoma via affecting LCN2/FPN1 signaling axis depended on NFKB2.

Lan Y, Yang T, Yue Q, Wang Z, Zhong X, Luo X, Zuo B, Zhang M, Zeng T, Liu B, Guo H
iScience 2023 Aug 18;26(8):107377

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A defective mechanosensing pathway affects fibroblast-to-myofibroblast transition in the old male mouse heart.

Angelini A, Trial J, Saltzman AB, Malovannaya A, Cieslik KA
iScience 2023 Aug 18;26(8):107283

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Warburg effect enhanced by AKR1B10 promotes acquired resistance to pemetrexed in lung cancer-derived brain metastasis.

Duan W, Liu W, Xia S, Zhou Y, Tang M, Xu M, Lin M, Li X, Wang Q
Journal of translational medicine 2023 Aug 16;21(1):547

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Design and discovery of new selective and potent VEGF receptor 2 tyrosine kinase inhibitors.

Hou F, Yao Y, Wei Y, Wang Y, Cao Y, Liu X, Zheng L, Zhang Q, Jiao Y, Chen Y, Meng Y, Sun Y, Wu Y, Wang J, Wang J, Wu Z, Zhang K, Wei M, Yang G
Bioorganic & medicinal chemistry 2023 Aug 15;91:117404

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PGAM5 deacetylation mediated by SIRT2 facilitates lipid metabolism and liver cancer proliferation.

Fu G, Li ST, Jiang Z, Mao Q, Xiong N, Li X, Hao Y, Zhang H
Acta biochimica et biophysica Sinica 2023 Aug 15;55(9):1370-1379

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FAAP100 is required for the resolution of transcription-replication conflicts in primordial germ cells.

Xu W, Yang Y, Yu Y, Wen C, Zhao S, Cao L, Zhao S, Qin Y, Chen ZJ
BMC biology 2023 Aug 15;21(1):174

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Estradiol mitigates stress-induced cardiac injury and inflammation by downregulating ADAM17 via the GPER-1/PI3K signaling pathway.

Adu-Amankwaah J, Bushi A, Tan R, Adekunle AO, Adzika GK, Ndzie Noah ML, Nadeem I, Adzraku SY, Koda S, Mprah R, Cui J, Li K, Wowui PI, Sun H
Cellular and molecular life sciences : CMLS 2023 Aug 12;80(9):246

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Structural and biochemical insights into the molecular mechanism of TRPT1 for nucleic acid ADP-ribosylation.

Yang X, Wang J, Li S, Li X, Gong J, Yan Z, Zhou H, Wu C, Liu X
Nucleic acids research 2023 Aug 11;51(14):7649-7665

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Correction: Tang et al. Vitamin K2 Modulates Mitochondrial Dysfunction Induced by 6-Hydroxydopamine in SH-SY5Y Cells via Mitochondrial Quality-Control Loop. Nutrients 2022, 14, 1504.

Tang H, Zheng Z, Wang H, Wang L, Zhao G, Wang P
Nutrients 2023 Aug 11;15(16)

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Intermittent fasting activates macrophage migration inhibitory factor and alleviates high-fat diet-induced nonalcoholic fatty liver disease.

Li D, Dun Y, Qi D, Ripley-Gonzalez JW, Dong J, Zhou N, Qiu L, Zhang J, Zeng T, You B, Liu S
Scientific reports 2023 Aug 11;13(1):13068

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Simiao San alleviates hyperuricemia and kidney inflammation by inhibiting NLRP3 inflammasome and JAK2/STAT3 signaling in hyperuricemia mice.

Zhang Y, Wang S, Dai X, Liu T, Liu Y, Shi H, Yin J, Xu T, Zhang Y, Zhao D, Sukhorukov V, Orekhov AN, Gao S, Wang L, Zhang D
Journal of ethnopharmacology 2023 Aug 10;312:116530

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Marein reduces lipid levels via modulating the PI3K/AKT/mTOR pathway to induce lipophagy.

Zhang PP, Zhuo BY, Duan ZW, Li X, Huang SL, Cao Q, Zhao T, Wei SL, Hu XH, Zhang Y
Journal of ethnopharmacology 2023 Aug 10;312:116523

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Nicotinamide Riboside Improves Stemness of Human Adipose-Derived Stem Cells and Inhibits Terminal Adipocyte Differentiation.

Chinnapaka S, Malekzadeh H, Tirmizi Z, Arellano JA, Ejaz A
Pharmaceuticals (Basel, Switzerland) 2023 Aug 10;16(8)

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Subchronic Arsenite Exposure Induced Atrophy and Erythropoietin Sensitivity Reduction in Skeletal Muscle Were Relevant to Declined Serum Melatonin Levels in Middle-Aged Rats.

Chen X, Chen W, Wang D, Ma L, Tao J, Zhang A
Toxics 2023 Aug 10;11(8)

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Repetitive Transcranial Magnetic Stimulation Improves Depression-like Behavior in Rats by Promoting Neural Stem Cell Proliferation and Differentiation.

Jiang C, Zheng S, Chen T, Li W, Zhang C, Gu S, Ren H, Huanhuan, Song J, Zhang Z
Neuroscience 2023 Aug 1;524:1-10

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Schisandrin B induces HepG2 cells pyroptosis by activating NK cells mediated anti-tumor immunity.

Song A, Ding T, Wei N, Yang J, Ma M, Zheng S, Jin H
Toxicology and applied pharmacology 2023 Aug 1;472:116574

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miR-147 Represses NDUFA4, Inducing Mitochondrial Dysfunction and Tubular Damage in Cold Storage Kidney Transplantation.

Zhu J, Xiang X, Hu X, Li C, Song Z, Dong Z
Journal of the American Society of Nephrology : JASN 2023 Aug 1;34(8):1381-1397

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Low-dose graphene oxide promotes tumor cells proliferation by activating PI3K-AKT-mTOR signaling via cellular membrane protein integrin αV.

Zheng Z, Halifu A, Ma J, Liu L, Fu Q, Yi B, Du E, Tian D, Xu Y, Zhang Z, Zhu J
Environmental pollution (Barking, Essex : 1987) 2023 Aug 1;330:121817

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Mucin2 regulated by Ho1/p38/IL-10 axis plays a protective role in polystyrene nanoplastics-mediated intestinal toxicity.

Cui M, He Q, Wang Z, Yu Y, Gao H, Liu Z, Peng H, Wang H, Zhang X, Li D, Chen L, Xing X, Xiao Y, Chen W, Wang Q
Environmental pollution (Barking, Essex : 1987) 2023 Aug 1;330:121808

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miR-342-5p promotes vascular smooth muscle cell phenotypic transition through a negative-feedback regulation of Notch signaling via targeting FOXO3.

Wen T, Duan Y, Gao D, Zhang X, Zhang X, Liang L, Yang Z, Zhang P, Zhang J, Sun J, Feng Y, Zheng Q, Han H, Yan X
Life sciences 2023 Aug 1;326:121828

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Repairing gastric ulcer with hyaluronic acid/extracellular matrix composite through promoting M2-type polarization of macrophages.

Ni R, Luo Y, Jiang L, Mao X, Feng Y, Tuersun S, Hu Z, Zhu Y
International journal of biological macromolecules 2023 Aug 1;245:125556

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A terrified-sound stress causes cognitive impairment in female mice by impairing neuronal plasticity.

Gao S, Zhang L, Wang X, Li R, Han L, Xiong X, Jiang Q, Cheng D, Xiao X, Li H, Yang J
Brain research 2023 Aug 1;1812:148419

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PARP16-Mediated Stabilization of Amyloid Precursor Protein mRNA Exacerbates Alzheimer's Disease Pathogenesis.

Wang J, Cheng Q, Zhang Y, Hong C, Liu J, Liu X, Chang J
Aging and disease 2023 Aug 1;14(4):1458-1471

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Houpo paiqi mixture promotes intestinal motility in constipated rats by modulating gut microbiota and activating 5-HT-cAMP-PKA signal pathway.

Wang R, Lu X, Zhao L, Zhang W, Zhang S
Journal of applied microbiology 2023 Aug 1;134(8)

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Weizmannia coagulans JA845 improves atherosclerosis induced by vitamin D3 and high-fat diet in rats through modulating lipid metabolism, oxidative stress, and endothelial vascular injury.

Ma L, Zhao Z, Zhao Y, Gao Y, Zhao L, Li S
Journal of applied microbiology 2023 Aug 1;134(8)

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The effect of PINK1/Parkin pathway on glucose homeostasis imbalance induced by tacrolimus in mouse livers.

Li Z, Xiang J, Mei S, Wu Y, Xu Y
Heliyon 2023 Apr;9(4):e15536

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Mitochondrial division inhibitor (mdivi-1) inhibits proliferation and epithelial-mesenchymal transition via the NF-κB pathway in thyroid cancer cells.

Zhang L, Sun L, Wang L, Wang J, Wang D, Jiang J, Zhang J, Zhou Q
Toxicology in vitro : an international journal published in association with BIBRA 2023 Apr;88:105552

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Therapeutic role of Artemether in the prevention of hepatic steatosis through miR-34a-5p/PPARα pathway.

Chen L, Yu S, Hong S, Lin X, Zhu X, Cao X, Li Y, Xiao H
Drug development research 2023 Apr;84(2):156-171

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Amnion-derived serum amyloid A1 participates in sterile inflammation of fetal membranes at parturition.

Lin YK, Zhang F, Lei WJ, Gan XW, Li MD, Pan F, Wang WS, Sun K
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Apr;72(4):797-812

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Synergistic activity and mechanism of cytarabine and MCL-1 inhibitor AZD5991 against acute myeloid leukemia.

Wang Y, Wang D, Wang Y, Yang H, Wang G, Wu S
Neoplasma 2023 Apr;70(2):287-293

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Osmoadaptive GLP-1R signalling in hypothalamic neurones inhibits antidiuretic hormone synthesis and release.

Greenwood MP, Greenwood M, Bárez-López S, Hawkins JW, Short K, Tatovic D, Murphy D
Molecular metabolism 2023 Apr;70:101692

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Holothuria leucospilota Polysaccharides Improve Immunity and the Gut Microbiota in Cyclophosphamide-Treated Immunosuppressed Mice.

Zhao F, Ma T, Zhang X, Zhao Q, Zhu K, Cao J, Liu Z, Shen X, Li C
Molecular nutrition & food research 2023 Apr;67(8):e2200317

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LncRNA CFAR promotes cardiac fibrosis via the miR-449a-5p/LOXL3/mTOR axis.

Zhang M, Zhang B, Wang X, Song J, Tong M, Dong Z, Xu J, Liu M, Jiang Y, Wang N, Wang Y, Du Z, Liu Y, Zhang R, Xu C
Science China. Life sciences 2023 Apr;66(4):783-799

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SNORD60 promotes the tumorigenesis and progression of endometrial cancer through binding PIK3CA and regulating PI3K/AKT/mTOR signaling pathway.

Wu W, Chen X, Liu X, Bao HJ, Li QH, Xian JY, Lu BF, Zhao Y, Chen S
Molecular carcinogenesis 2023 Apr;62(4):413-426

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FUT2-dependent fucosylation of HYOU1 protects intestinal stem cells against inflammatory injury by regulating unfolded protein response.

Wang Z, Tan C, Duan C, Wu J, Zhou D, Hou L, Qian W, Han C, Hou X
Redox biology 2023 Apr;60:102618

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Sensitive and quantitative in vivo analysis of PD-L1 using magnetic particle imaging and imaging-guided immunotherapy.

Peng Z, Lu C, Shi G, Yin L, Liang X, Song G, Tian J, Du Y
European journal of nuclear medicine and molecular imaging 2023 Apr;50(5):1291-1305

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PGAM4 silencing inhibited glycolysis and chemoresistance to temozolomide in glioma cells.

Lu B, Nie XH, Yin R, Ding P, Su ZZ, Qiu S, Qian YF
Cell biology international 2023 Apr;47(4):776-786

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Hederagenin Suppresses Inflammation and Cartilage Degradation to Ameliorate the Progression of Osteoarthritis: An In vivo and In vitro Study.

Shen Y, Teng L, Qu Y, Huang Y, Peng Y, Tang M, Fu Q
Inflammation 2023 Apr;46(2):655-678

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Reciprocal FGF19-GLI2 signaling induces epithelial-to-mesenchymal transition to promote lung squamous cell carcinoma metastasis.

Zhang Y, Wu T, Wang Y, Chen Z, Chen J, Lu S, Xia W
Cellular oncology (Dordrecht, Netherlands) 2023 Apr;46(2):437-450

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Activation of TRPV1 receptor facilitates myelin repair following demyelination via the regulation of microglial function.

Sun JX, Zhu KY, Wang YM, Wang DJ, Zhang MZ, Sarlus H, Benito-Cuesta I, Zhao XQ, Zou ZF, Zhong QY, Feng Y, Wu S, Wang YQ, Harris RA, Wang J
Acta pharmacologica Sinica 2023 Apr;44(4):766-779

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NONO regulates B-cell development and B-cell receptor signaling.

Zhang Y, Cui D, Huang M, Zheng Y, Zheng B, Chen L, Chen Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Apr;37(4):e22862

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P4HA2-mediated HIF-1α stabilization promotes erdafitinib-resistance in FGFR3-alteration bladder cancer.

Li X, Li Y, Liu B, Chen L, Lyu F, Zhang P, He Q, Cheng L, Liu C, Song Y, Xing Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Apr;37(4):e22840

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Perilla frutescens L. alleviates trimethylamine N-oxide-induced apoptosis in the renal tubule by regulating ASK1-JNK phosphorylation.

Yong C, Huang G, Ge H, Zhu Y, Yang Y, Yu Y, Tian F, Gao K, Zhou E
Phytotherapy research : PTR 2023 Apr;37(4):1274-1292

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Reshaping the Endogenous Electric Field to Boost Wound Repair via Electrogenerative Dressing.

Luo R, Liang Y, Yang J, Feng H, Chen Y, Jiang X, Zhang Z, Liu J, Bai Y, Xue J, Chao S, Xi Y, Liu X, Wang E, Luo D, Li Z, Zhang J
Advanced materials (Deerfield Beach, Fla.) 2023 Apr;35(16):e2208395

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Influence of cyclin D1 splicing variants expression on breast cancer chemoresistance via CDK4/CyclinD1-pRB-E2F1 pathway.

Wang J, Zhang J, Ma Q, Zhang S, Ma F, Su W, Zhang T, Xie X, Di C
Journal of cellular and molecular medicine 2023 Apr;27(7):991-1005

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Kaempferol promotes melanogenesis and reduces oxidative stress in PIG1 normal human skin melanocytes.

Xie Y, Mei X, Shi W
Journal of cellular and molecular medicine 2023 Apr;27(7):982-990

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Tax1 binding protein 3 regulates osteogenic and adipogenic differentiation through inactivating Wnt/β-catenin signalling.

Wang Y, Gan Y, Dong Y, Zhou J, Zhu E, Yuan H, Li X, Wang B
Journal of cellular and molecular medicine 2023 Apr;27(7):950-961

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Knockdown of the long non‑coding RNA MALAT1 ameliorates TNF‑α‑mediated endothelial cell pyroptosis via the miR‑30c‑5p/Cx43 axis.

Yang ZJ, Liu R, Han XJ, Qiu CL, Dong GL, Liu ZQ, Liu LH, Luo Y, Jiang LP
Molecular medicine reports 2023 Apr;27(4)

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Hydroxysafflor Yellow A Exerts Neuroprotective Effect by Reducing Aβ Toxicity Through Inhibiting Endoplasmic Reticulum Stress in Oxygen-Glucose Deprivation/Reperfusion Cell Model.

Ma HH, Wen JR, Fang H, Su S, Wan C, Zhang C, Lu FM, Fan LL, Wu GL, Zhou ZY, Qiao LJ, Zhang SJ, Cai YF
Rejuvenation research 2023 Apr;26(2):57-67

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LPS inhibits TRIM65 expression in macrophages and C57BL/6J mouse by activating the ERK1/2 signaling pathway.

Zeng X, Deng X, Ni Y, Bi H, Jiang M, Wang D, Dong P, Xiao Y, Jiang M
Experimental and therapeutic medicine 2023 Apr;25(4):188

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Low expression of SEMA4D as a potential predictive molecular marker of poor survival in patients with melanoma combined with liver cancer.

Liu X, Zhang C, Yang WH, Li SC, Wang RF, Zhang YB, Zhang ZL
Oncology letters 2023 Apr;25(4):160

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PSKH1 affects proliferation and invasion of osteosarcoma cells via the p38/MAPK signaling pathway.

Zhu X, Jiang C, Wang Z, Zhu X, Yuan F, Yang Y
Oncology letters 2023 Apr;25(4):144

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MiR-133a/CD47 axis is a novel prognostic biomarker to promote triple negative breast cancer progression.

Yan H, Huang W, Chen C, Zhang X, Zhu K, Yuan J
Pathology, research and practice 2023 Apr;244:154400

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CircHGS enhances the progression of bladder cancer by regulating the miR-513a-5p/VEGFC axis and activating the AKT/mTOR signaling pathway.

Zhu Y, Zuo L, Xiong H, Li S, Chen R, Liu H
Cell cycle (Georgetown, Tex.) 2023 Apr;22(8):919-938

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Dimethyl fumarate protects against hepatic ischemia-reperfusion injury by alleviating ferroptosis via the NRF2/SLC7A11/HO-1 axis.

Qi D, Chen P, Bao H, Zhang L, Sun K, Song S, Li T
Cell cycle (Georgetown, Tex.) 2023 Apr;22(7):818-828

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ADAMTS12 promotes migration and epithelial-mesenchymal transition and predicts poor prognosis for pancreatic cancer.

He RZ, Zheng JH, Yao HF, Xu DP, Yang MW, Liu DJ, Sun YW, Huo YM
Hepatobiliary & pancreatic diseases international : HBPD INT 2023 Apr;22(2):169-178

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Lenvatinib inhibited HCC cell migration and invasion through regulating the transcription and ubiquitination of UHRF1 and DNMT1.

Fang T, Jiao Z, You Y, Cao J, Wang C, Liu J, Zhao W
Biochemical pharmacology 2023 Apr;210:115489

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Oncogenic FLT3 internal tandem duplication activates E2F1 to regulate purine metabolism in acute myeloid leukaemia.

Ou ZY, Wang K, Shen WW, Deng G, Xu YY, Wang LF, Zai ZY, Ling YA, Zhang T, Peng XQ, Chen FH
Biochemical pharmacology 2023 Apr;210:115458

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Selenoprotein Gene mRNA Expression Evaluation During Renal Ischemia-Reperfusion Injury in Rats and Ebselen Intervention Effects.

Wu Y, Shi H, Xu Y, Wen R, Gong M, Hong G, Xu S
Biological trace element research 2023 Apr;201(4):1792-1805

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HTR2A agonists play a therapeutic role by restricting ILC2 activation in papain-induced lung inflammation.

Wang Z, Yan C, Du Q, Huang Y, Li X, Zeng D, Mao R, Gurram RK, Cheng S, Gu W, Zhu L, Fan W, Ma L, Ling Z, Qiu J, Li D, Liu E, Zhang Y, Fang Y, Zhu J, Sun B
Cellular & molecular immunology 2023 Apr;20(4):404-418

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Fluorescent visualization and evaluation of NPC1L1-mediated vesicular endocytosis during intestinal cholesterol absorption in mice.

Wu X, Ma XH, Lin J, Yang X, Shi JH, Xie Z, Chen YX, Zhang WJ
Life metabolism 2023 Apr;2(2):load011

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Selenoprotein K enhances STING oligomerization to facilitate antiviral response.

Lv L, Chai L, Wang J, Wang M, Qin D, Song H, Fu Y, Zhao C, Jia J, Zhao W, Jia M
PLoS pathogens 2023 Apr;19(4):e1011314

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FOXP3+ macrophage represses acute ischemic stroke-induced neural inflammation.

Cai W, Hu M, Li C, Wu R, Lu D, Xie C, Zhang W, Li T, Shen S, Huang H, Qiu W, Liu Q, Lu Y, Lu Z
Autophagy 2023 Apr;19(4):1144-1163

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Necroptosis plays a crucial role in the exacerbation of retinal injury after blunt ocular trauma.

Huan Y, Wu XQ, Chen T, Dou YN, Jia B, He X, Wei DY, Fei Z, Fei F
Neural regeneration research 2023 Apr;18(4):922-928

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Identification and functional analysis of three novel genetic variants resulting in premature termination codons in three unrelated patients with hereditary antithrombin deficiency.

Imai Y, Nagaya S, Araiso Y, Meguro-Horike M, Togashi T, Ohmori K, Makita Y, Sato E, Yujiri T, Nagamori Y, Horike SI, Watanabe A, Morishita E
International journal of hematology 2023 Apr;117(4):523-529

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EGFR-TNFR1 pathway in endothelial cell facilitates acute lung injury by NF-κB/MAPK-mediated inflammation and RIP3-dependent necroptosis.

Zhang H, Zhang X, Ling C, Liu C, Hua S, Xiong Z, Zhao H, Feng Q, Feng Z, Tang J, Hong X
International immunopharmacology 2023 Apr;117:109902

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ARID1B blocks methionine-stimulated mTOR activation to inhibit milk fat and protein synthesis in and proliferation of mouse mammary epithelial cells.

Lin G, Qi H, Guo X, Wang W, Zhang M, Gao X
The Journal of nutritional biochemistry 2023 Apr;114:109274

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Acinetobacter baumannii outer membrane protein A induces autophagy in bone marrow-derived dendritic cells involving the PI3K/mTOR pathway.

Tan H, Cao L
Immunity, inflammation and disease 2023 Apr;11(4):e830

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Engineered Extracellular Vesicle-Delivered CRISPR/CasRx as a Novel RNA Editing Tool.

Li T, Zhang L, Lu T, Zhu T, Feng C, Gao N, Liu F, Yu J, Chen K, Zhong J, Tang Q, Zhang Q, Deng X, Ren J, Zeng J, Zhou H, Zhu J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Apr;10(10):e2206517

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Wei-Tong-Xin exerts anti-inflammatory effects through TLR4-mediated macrophages M1/M2 polarization and affects GLP-1 secretion.

Zhang X, Yang X, Zhang S, Wang J, Wang M, Ma T, Wan M, Lv X, Yan T, Jia Y
The Journal of pharmacy and pharmacology 2023 Apr 7;75(4):574-584

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ZSWIM1 Promotes the Proliferation and Metastasis of Lung Adenocarcinoma Cells through the STK38/MEKK2/ERK1/2 Axis.

Gao X, Lian Q, Guan B, Liu QY, Meng M, Chen Y, Jin J, Li H, Liu X, Sun Z, Liu L, He QY, Zhang G
Journal of proteome research 2023 Apr 7;22(4):1080-1091

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Integrated network pharmacology and experimental verification to explore the molecular mechanism of Jingxin Zhidong formula for treating Tic disorder.

Tian X, Ou G, Hu S, Wang C, Han F, Gao L
Journal of ethnopharmacology 2023 Apr 6;305:116114

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Identification of hub genes and pathways in lung metastatic colorectal cancer.

Dai W, Guo C, Wang Y, Li Y, Xie R, Wu J, Yao B, Xie D, He L, Li Y, Huang H, Wang Y, Liu S
BMC cancer 2023 Apr 6;23(1):323

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RNF20 is required for male fertility through regulation of H2B ubiquitination in the Sertoli cells.

Lai F, Wang H, Zhao X, Yang K, Cai L, Hu M, Lin L, Xia X, Li W, Cheng H, Zhou R
Cell & bioscience 2023 Apr 6;13(1):71

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Goliath induces inflammation in obese mice by linking fatty acid β-oxidation to glycolysis.

Hao S, Zhang S, Ye J, Chen L, Wang Y, Pei S, Zhu Q, Xu J, Tao Y, Zhou N, Yin H, Duan CW, Mao C, Zheng M, Xiao Y
EMBO reports 2023 Apr 5;24(4):e56932

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Ligation to Scavenging Strategy Enables On-Demand Termination of Targeted Protein Degradation.

Jin Y, Fan J, Wang R, Wang X, Li N, You Q, Jiang Z
Journal of the American Chemical Society 2023 Apr 5;145(13):7218-7229

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Lateral septum adenosine A(2A) receptors control stress-induced depressive-like behaviors via signaling to the hypothalamus and habenula.

Wang M, Li P, Li Z, da Silva BS, Zheng W, Xiang Z, He Y, Xu T, Cordeiro C, Deng L, Dai Y, Ye M, Lin Z, Zhou J, Zhou X, Ye F, Cunha RA, Chen J, Guo W
Nature communications 2023 Apr 5;14(1):1880

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Characterization of dominant-negative growth hormone receptor variants reveals a potential therapeutic target for short stature.

Andrews A, Cottrell E, Maharaj A, Ladha T, Williams J, Schilbach K, Kaisinger LR, Perry JRB, Metherell LA, McCormick PJ, Storr HL
European journal of endocrinology 2023 Apr 4;188(4):353-365

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Heat-Killed Lacticaseibacillus paracasei Repairs Lipopolysaccharide-Induced Intestinal Epithelial Barrier Damage via MLCK/MLC Pathway Activation.

Xie Z, Zhang G, Liu R, Wang Y, Tsapieva AN, Zhang L, Han J
Nutrients 2023 Apr 4;15(7)

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Aqueous-soluble components of sporoderm-removed Ganoderma lucidum spore powder promote ferroptosis in oral squamous cell carcinoma.

Wu X, Wu Q, Wang Y, Liu Y, Li Z, Liu Q, Huang Z, Li M, Zhang B, Zhan Q
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2023 Apr 30;35(2):176-190

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Donkey Oil-Based Ketogenic Diet Prevents Tumor Progression by Regulating Intratumor Inflammation, Metastasis and Angiogenesis in CT26 Tumor-Bearing Mice.

Zhang H, Xie L, Zhang N, Qi X, Lu T, Xing J, Akhtar MF, Li L, Liu G
Genes 2023 Apr 30;14(5)

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The outer mitochondrial membrane protein TMEM11 demarcates spatially restricted BNIP3/BNIP3L-mediated mitophagy.

Gok MO, Connor OM, Wang X, Menezes CJ, Llamas CB, Mishra P, Friedman JR
The Journal of cell biology 2023 Apr 3;222(4)

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Knockdown of the SELENOK gene induces ferroptosis in cervical cancer cells.

Abdurahman A, Li Y, Jia SZ, Xu XW, Lin SJ, Ouyang P, Jun He Z, Zhang ZH, Liu Q, Xu Y, Song GL
Metallomics : integrated biometal science 2023 Apr 3;15(4)

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Caffeine can alleviate non-alcoholic fatty liver disease by augmenting LDLR expression via targeting EGFR.

Huang YW, Wang LT, Zhang M, Nie Y, Yang JB, Meng WL, Wang XJ, Sheng J
Food & function 2023 Apr 3;14(7):3269-3278

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Upregulation of carbonic anhydrase 1 beneficial for depressive disorder.

Cheng K, Wang Y, He Y, Tian Y, Li J, Chen C, Xu X, Wu Z, Yu H, Chen X, Wu Y, Song W, Dong Z, Xu H, Xie P
Acta neuropathologica communications 2023 Apr 3;11(1):59

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Identification of glutamyl-prolyl-tRNA synthetase as a new therapeutic target in hepatocellular carcinoma via a novel bioinformatic approach.

Shu J, Luo P, Zhang G, Gao Y
Journal of gastrointestinal oncology 2023 Apr 29;14(2):636-649

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Dual role of PID1 in regulating apoptosis induced by distinct anticancer-agents through AKT/Raf-1-dependent pathway in hepatocellular carcinoma.

Yang J, Li S, He J, Xu Q, Xie M, Yang C, Wang H, Zhang Y, Wan Q, Xiang M
Cell death discovery 2023 Apr 28;9(1):139

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N(6)-methyladenosine reader IGF2BP3 as a prognostic Biomarker contribute to malignant progression of glioma.

Zheng X, Li S, Yu J, Dai C, Yan S, Chen G, Sun C
Translational cancer research 2023 Apr 28;12(4):992-1005

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Acinous cell AR42J-derived exosome miR125b-5p promotes acute pancreatitis exacerbation by inhibiting M2 macrophage polarization via PI3K/AKT signaling pathway.

Zheng Z, Cao F, Ding YX, Lu JD, Fu YQ, Liu L, Guo YL, Liu S, Sun HC, Cui YQ, Li F
World journal of gastrointestinal surgery 2023 Apr 27;15(4):600-620

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MAVS-Based Reporter Systems for Real-Time Imaging of EV71 Infection and Antiviral Testing.

Li X, Yang E, Li X, Fan T, Guo S, Yang H, Wu B, Wang H
Viruses 2023 Apr 26;15(5)

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The complement inhibitor CD59 is required for GABAergic synaptic transmission in the dentate gyrus.

Wen L, Yang X, Wu Z, Fu S, Zhan Y, Chen Z, Bi D, Shen Y
Cell reports 2023 Apr 25;42(4):112349

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Synergistic effect of constituent drugs of Baibutang on improving Yin-deficiency pulmonary fibrosis in rats.

Fu S, Song X, Tang X, Qian X, Du Z, Hu Y, Xu X, Zhang M
Journal of ethnopharmacology 2023 Apr 24;306:116050

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Progerinin, an Inhibitor of Progerin, Alleviates Cardiac Abnormalities in a Model Mouse of Hutchinson-Gilford Progeria Syndrome.

Kang SM, Seo S, Song EJ, Kweon O, Jo AH, Park S, Woo TG, Kim BH, Oh GT, Park BJ
Cells 2023 Apr 24;12(9)

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Sleeve gastrectomy decreased hepatic lipid accumulation by inducing autophagy via AMPK/mTOR pathway.

Zeng R, Zeng Y, Wang Q, Li X, Liu J, Li B, Zhang G, Hu S
Biochemical and biophysical research communications 2023 Apr 23;653:115-125

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In situ isolation of nuclei or nuclear proteins from adherent cells: a simple, effective method with less cytoplasmic contamination.

Qin Y, Zhou Y, Wang K, Gu J, Xiong Z, Zhang W, Chen Y
Biological research 2023 Apr 21;56(1):18

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Human Cytomegalovirus UL23 Antagonizes the Antiviral Effect of Interferon-γ by Restraining the Expression of Specific IFN-Stimulated Genes.

Wang H, Peng W, Wang J, Zhang C, Zhao W, Ran Y, Yang X, Chen J, Li H
Viruses 2023 Apr 20;15(4)

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Protective Effect of Lonicera japonica on PM(2.5)-Induced Pulmonary Damage in BALB/c Mice via the TGF-β and NF-κB Pathway.

Lee HL, Kim JM, Go MJ, Kim TY, Joo SG, Kim JH, Lee HS, Kim HJ, Heo HJ
Antioxidants (Basel, Switzerland) 2023 Apr 20;12(4)

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NLRP3 Plays a Key Role in Antihelminth Immunity in the Enteral and Parenteral Stages of Trichinella spiralis-Infected Mice.

Pan TX, Huang HB, Lu HN, Zhao GX, Quan Y, Li JY, Xue Y, Zhu ZY, Wang Y, Shi CW, Wang N, Yang GL, Wang CF
Infection and immunity 2023 Apr 18;91(4):e0038222

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p53 protects against alcoholic fatty liver disease via ALDH2 inhibition.

Yao P, Zhang Z, Liu H, Jiang P, Li W, Du W
The EMBO journal 2023 Apr 17;42(8):e112304

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Phosphorylation and stabilization of EZH2 by DCAF1/VprBP trigger aberrant gene silencing in colon cancer.

Ghate NB, Kim S, Shin Y, Kim J, Doche M, Valena S, Situ A, Kim S, Rhie SK, Lenz HJ, Ulmer TS, Mumenthaler SM, An W
Nature communications 2023 Apr 17;14(1):2140

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Vimar/RAP1GDS1 promotes acceleration of brain aging after flies and mice reach middle age.

Xiong Y, Cheng Q, Li Y, Han Y, Sun X, Liu L
Communications biology 2023 Apr 15;6(1):420

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Mitoglitazone ameliorates renal ischemia/reperfusion injury by inhibiting ferroptosis via targeting mitoNEET.

Qi Y, Hu M, Qiu Y, Zhang L, Yan Y, Feng Y, Feng C, Hou X, Wang Z, Zhang D, Zhao J
Toxicology and applied pharmacology 2023 Apr 15;465:116440

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cGAS Mediates Inflammation by Polarizing Macrophages to M1 Phenotype via the mTORC1 Pathway.

Shen X, Sun C, Cheng Y, Ma D, Sun Y, Lin Y, Zhao Y, Yang M, Jing W, Cui X, Han L
Journal of immunology (Baltimore, Md. : 1950) 2023 Apr 15;210(8):1098-1107

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High-cholesterol diet promotes depression- and anxiety-like behaviors in mice by impact gut microbe and neuroinflammation.

Zou L, Tian Y, Wang Y, Chen D, Lu X, Zeng Z, Chen Z, Lin C, Liang Y
Journal of affective disorders 2023 Apr 14;327:425-438

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Resveratrol induces proliferation and differentiation of mouse pre-osteoblast MC3T3-E1 by promoting autophagy.

Cai W, Sun B, Song C, Liu F, Wu Z, Liu Z
BMC complementary medicine and therapies 2023 Apr 14;23(1):121

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EPC-exosomal miR-26a-5p improves airway remodeling in COPD by inhibiting ferroptosis of bronchial epithelial cells via PTGS2/PGE2 signaling pathway.

Liu C, Lu J, Yuan T, Xie L, Zhang L
Scientific reports 2023 Apr 14;13(1):6126

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Immunophenotyping of Monocyte Migration Markers and Therapeutic Effects of Selenium on IL-6 and IL-1β Cytokine Axes of Blood Mononuclear Cells in Preoperative and Postoperative Coronary Artery Disease Patients.

Wacker M, Ball A, Beer HD, Schmitz I, Borucki K, Azizzadeh F, Scherner M, Awad G, Wippermann J, Veluswamy P
International journal of molecular sciences 2023 Apr 13;24(8)

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TIGD1 Function as a Potential Cuproptosis Regulator Following a Novel Cuproptosis-Related Gene Risk Signature in Colorectal Cancer.

Wu Z, Lin C, Zhang F, Lu Z, Wang Y, Liu Y, Zhou Z, Li L, Song L
Cancers 2023 Apr 13;15(8)

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Porcine Epidemic Diarrhea Virus Replication in Human Intestinal Cells Reveals Potential Susceptibility to Cross-Species Infection.

Niu Z, Zhang S, Xu S, Wang J, Wang S, Hu X, Zhang L, Ren L, Zhang J, Liu X, Zhou Y, Yang L, Song Z
Viruses 2023 Apr 13;15(4)

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Menstrual blood-derived endometrial stem cells alleviate neuroinflammation by modulating M1/M2 polarization in cell and rat Parkinson's disease models.

Li H, Wei J, Zhang Z, Li J, Ma Y, Zhang P, Lin J
Stem cell research & therapy 2023 Apr 13;14(1):85

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Excessive serine from the bone marrow microenvironment impairs megakaryopoiesis and thrombopoiesis in Multiple Myeloma.

Kuang C, Xia M, An G, Liu C, Hu C, Zhang J, Liu Z, Meng B, Su P, Xia J, Guo J, Zhu Y, Liu X, Wu X, Shen Y, Feng X, He Y, Li J, Qiu L, Zhou J, Zhou W
Nature communications 2023 Apr 13;14(1):2093

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The Construction and Immunogenicity Analyses of a Recombinant Pseudorabies Virus with Senecavirus A VP2 Protein Coexpression.

Tao Q, Zhu L, Xu L, Yang Y, Zhang Y, Liu Z, Xu T, Wen J, Deng L, Zhou Y, Xu Z
Microbiology spectrum 2023 Apr 13;11(2):e0522922

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Disruption of the Intestinal Mucosal Barrier Induced by High Fructose and Restraint Stress Is Regulated by the Intestinal Microbiota and Microbiota Metabolites.

Yu J, Liu T, Guo Q, Wang Z, Chen Y, Dong Y
Microbiology spectrum 2023 Apr 13;11(2):e0469822

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Vascular Endothelial Growth Factor A Contributes to Increased Mammalian Respiratory Epithelial Permeability Induced by Pasteurella multocida Infection.

Lin L, Yang J, Zhang D, Lv Q, Wang F, Liu P, Wang M, Shi C, Huang X, Liang W, Tan C, Wang X, Chen H, Wilson BA, Wu B, Peng Z
Microbiology spectrum 2023 Apr 13;11(2):e0455422

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Xiaoyaosan ameliorates depressive-like behavior and susceptibility to glucose intolerance in rat: involvement of LepR-STAT3/PI3K pathway in hypothalamic arcuate nucleus.

Qiu W, Wu Q, Zhang K, Da X, Tang K, Yuan N, Deng L, Wu M, Zhang Y, Quan J, Ma Q, Li X, Chen J
BMC complementary medicine and therapies 2023 Apr 12;23(1):116

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Hepatic G Protein-Coupled Receptor 180 Deficiency Ameliorates High Fat Diet-Induced Lipid Accumulation via the Gi-PKA-SREBP Pathway.

Zhang Y, Zhu Z, Sun L, Yin W, Liang Y, Chen H, Bi Y, Zhai W, Yin Y, Zhang W
Nutrients 2023 Apr 11;15(8)

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Deregulation of ER-mitochondria contact formation and mitochondrial calcium homeostasis mediated by VDAC in fragile X syndrome.

Geng J, Khaket TP, Pan J, Li W, Zhang Y, Ping Y, Cobos Sillero MI, Lu B
Developmental cell 2023 Apr 10;58(7):597-615.e10

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Palmitoyl transferases act as novel drug targets for pancreatic cancer.

Lin Z, Lv Z, Liu X, Huang K
Journal of translational medicine 2023 Apr 10;21(1):249

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ME2 Promotes Hepatocellular Carcinoma Cell Migration through Pyruvate.

Yang Y, Zhang Z, Li W, Li L, Zhou Y, Du W
Metabolites 2023 Apr 10;13(4)

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Exosomal circCLIP1 regulates PM(2.5)-induced airway obstruction via targeting SEPT10 in vitro.

Zhu H, Tang X, Zhang H, Zhou M, Liu H, Chu H, Zhang Z
Ecotoxicology and environmental safety 2023 Apr 1;254:114750

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Subchronic Microcystin-LR Aggravates Colorectal Inflammatory Response and Barrier Disruption via Raf/ERK Signaling Pathway in Obese Mice.

Yang Y, Zheng S, Chu H, Du C, Chen M, Emran MY, Chen J, Yang F, Tian L
Toxins 2023 Apr 1;15(4)

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Identification of FEZ2 as a potential oncogene in pancreatic ductal adenocarcinoma.

Yang C, Wang X, Qiu C, Zheng Z, Lin K, Tu M, Zhang K, Jiang K, Gao W
PeerJ 2022;9:e12736

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Role of TRPV1 ion channel in cervical squamous cell carcinoma genesis.

Wang Z, Dong J, Tian W, Qiao S, Wang H
Frontiers in molecular biosciences 2022;9:980262

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Identification of amino acid residues in the MT-loop of MT1-MMP critical for its ability to cleave low-density lipoprotein receptor.

Wang M, Alabi A, Gu HM, Gill G, Zhang Z, Jarad S, Xia XD, Shen Y, Wang GQ, Zhang DW
Frontiers in cardiovascular medicine 2022;9:917238

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Structural Characterization and Anti-breast Cancer Activity in vitro of a Novel Polysaccharide From Cymbopogon citratus.

Chen Y, Qiao S, Liu H, Xing H, Chen P
Frontiers in nutrition 2022;9:911838

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Sodium-glucose cotransporter-2 inhibitor alleviated atrial remodeling in STZ-induced diabetic rats by targeting TLR4 pathway.

Zhan X, Cheng L, Huo N, Yu L, Liu C, Liu T, Li G, Fu H
Frontiers in cardiovascular medicine 2022;9:908037

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The Protective Effect of Sulforaphane on Dextran Sulfate Sodium-Induced Colitis Depends on Gut Microbial and Nrf2-Related Mechanism.

He C, Gao M, Zhang X, Lei P, Yang H, Qing Y, Zhang L
Frontiers in nutrition 2022;9:893344

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(-)-Epicatechin Provides Neuroprotection in Sodium Iodate-Induced Retinal Degeneration.

Peng M, Zhou X, Yao F, Li H, Song W, Xiong S, Xia X
Frontiers in medicine 2022;9:879901

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Isoliquiritin Ameliorates Cisplatin-Induced Renal Proximal Tubular Cell Injury by Antagonizing Apoptosis, Oxidative Stress and Inflammation.

Pei Z, Wu M, Yu H, Long G, Gui Z, Li X, Chen H, Jia Z, Xia W
Frontiers in medicine 2022;9:873739

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Momordica. charantia-Derived Extracellular Vesicles-Like Nanovesicles Protect Cardiomyocytes Against Radiation Injury via Attenuating DNA Damage and Mitochondria Dysfunction.

Cui WW, Ye C, Wang KX, Yang X, Zhu PY, Hu K, Lan T, Huang LY, Wang W, Gu B, Yan C, Ma P, Qi SH, Luo L
Frontiers in cardiovascular medicine 2022;9:864188

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Ornithine α-Ketoglutarate Alleviates Inflammation via Regulating Ileal Mucosa Microbiota and Metabolites in Enterotoxigenic Escherichia coli-Infected Pigs.

Li Y, Bao X, Yang F, Tian J, Su W, Yin J, Yao K, Li T, Yin Y
Frontiers in nutrition 2022;9:862498

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The Mechanism of Lipopolysaccharide Escaping the Intestinal Barrier in Megalobrama amblycephala Fed a High-Fat Diet.

Dai YJ, Liu WB, Abasubong KP, Zhang DD, Li XF, Xiao K, Wang X, Jiang GZ
Frontiers in nutrition 2022;9:853409

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Berberine Ameliorates Inflammation in Acute Lung Injury via NF-κB/Nlrp3 Signaling Pathway.

Chen J, Huang Y, Bian X, He Y
Frontiers in nutrition 2022;9:851255

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Effects of Excessive Activation of N-methyl-D-aspartic Acid Receptors in Neonatal Cardiac Mitochondrial Dysfunction Induced by Intrauterine Hypoxia.

Liu Y, Luo Z, Liao Z, Wang M, Zhou Y, Luo S, Ding Y, Liu T, Cao C, Yue S
Frontiers in cardiovascular medicine 2022;9:837142

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Metabolomic Profile Reveals That Ceramide Metabolic Disturbance Plays an Important Role in Thoracic Aortic Dissection.

Yang H, Yang F, Luo M, Chen Q, Liu X, Zhang Y, Zhu G, Chen W, Li T, Shu C, Zhou Z
Frontiers in cardiovascular medicine 2022;9:826861

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Selective Cleavage at CCA Ends and Anticodon Loops of tRNAs by Stress-Induced RNases.

Akiyama Y, Lyons SM, Fay MM, Tomioka Y, Abe T, Anderson PJ, Ivanov P
Frontiers in molecular biosciences 2022;9:791094

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Expression of the Immune Checkpoint Protein VISTA Is Differentially Regulated by the TGF-β1 - Smad3 Signaling Pathway in Rapidly Proliferating Human Cells and T Lymphocytes.

Schlichtner S, Yasinska IM, Ruggiero S, Berger SM, Aliu N, Prunk M, Kos J, Meyer NH, Gibbs BF, Fasler-Kan E, Sumbayev VV
Frontiers in medicine 2022;9:790995

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Melatonin Engineered Adipose-Derived Biomimetic Nanovesicles Regulate Mitochondrial Functions and Promote Myocardial Repair in Myocardial Infarction.

Zhang Y, Yang N, Huang X, Zhu Y, Gao S, Liu Z, Cao F, Wang Y
Frontiers in cardiovascular medicine 2022;9:789203

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Dishevelled-Associated Activator of Morphogenesis 2 (DAAM2) Predicts the Immuno-Hot Phenotype in Pancreatic Adenocarcinoma.

Zhang Q, Pan J, Nie H, Wang H, An F, Zhan Q
Frontiers in molecular biosciences 2022;9:750083

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Differential Expression Profile of microRNAs and Tight Junction in the Lung Tissues of Rat With Mitomycin-C-Induced Pulmonary Veno-Occlusive Disease.

Song Q, Chen P, Wu SJ, Chen Y, Zhang Y
Frontiers in cardiovascular medicine 2022;9:746888

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Molecular and Cellular Response of the Myocardium (H9C2 Cells) Towards Hypoxia and HIF-1α Inhibition.

Osuru HP, Lavallee M, Thiele RH
Frontiers in cardiovascular medicine 2022;9:711421

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Cryptotanshinone attenuates LPS-induced acute lung injury by regulating metabolic reprogramming of macrophage.

Ye Z, Wang P, Feng G, Wang Q, Liu C, Lu J, Chen J, Liu P
Frontiers in medicine 2022;9:1075465

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Exosomes derived from M2 macrophages induce angiogenesis to promote wound healing.

Lyu L, Cai Y, Zhang G, Jing Z, Liang J, Zhang R, Dang X, Zhang C
Frontiers in molecular biosciences 2022;9:1008802

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Metabolic Reprogramming of Microglia Enhances Proinflammatory Cytokine Release through EphA2/p38 MAPK Pathway in Alzheimer's Disease.

Ma X, Zhang Y, Gou D, Ma J, Du J, Wang C, Li S, Cui H
Journal of Alzheimer's disease : JAD 2022;88(2):771-785

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Probiotic Bifidobacterium breve Prevents Memory Impairment Through the Reduction of Both Amyloid-β Production and Microglia Activation in APP Knock-In Mouse.

Abdelhamid M, Zhou C, Ohno K, Kuhara T, Taslima F, Abdullah M, Jung CG, Michikawa M
Journal of Alzheimer's disease : JAD 2022;85(4):1555-1571

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Administration of miR-195 Inhibitor Enhances Memory Function Through Improving Synaptic Degradation and Mitochondrial Dysfunction of the Hippocampal Neurons in SAMP8 Mice.

Gao Z, Zhang R, Jiang L, Zhou H, Wang Q, Ma Y, Zhang D, Qin Y, Tian P, Zhang N, Shi Z, Xu S
Journal of Alzheimer's disease : JAD 2022;85(4):1495-1509

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Spatial Training Attenuates Long-Term Alzheimer's Disease-Related Pathogenic Processes in APP/PS1 Mice.

Zhao Y, Bao J, Liu W, Gong X, Liang Z, Li W, Wu M, Xiao Y, Sun B, Wang X, Wang JZ, Wang J, Shu X
Journal of Alzheimer's disease : JAD 2022;85(4):1453-1466

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3D-Printed β-Tricalcium Phosphate Scaffolds Promote Osteogenic Differentiation of Bone Marrow-Deprived Mesenchymal Stem Cells in an N6-methyladenosine-Dependent Manner.

Jiao X, Sun X, Li W, Chu W, Zhang Y, Li Y, Wang Z, Zhou X, Ma J, Xu C, Dai K, Wang J, Gan Y
International journal of bioprinting 2022;8(2):544

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Antitumor Effects of Astaxanthin on Esophageal Squamous Cell Carcinoma by up-Regulation of PPARγ.

Cui L, Li Z, Xu F, Tian Y, Chen T, Li J, Guo Y, Lyu Q
Nutrition and cancer 2022;74(4):1399-1410

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Lactobacillus acidophilus ATCC 4356 Exopolysaccharides Suppresses Mediators of Inflammation through the Inhibition of TLR2/STAT-3/P38-MAPK Pathway in DEN-Induced Hepatocarcinogenesis in Rats.

Khedr OMS, El-Sonbaty SM, Moawed FSM, Kandil EI, Abdel-Maksoud BE
Nutrition and cancer 2022;74(3):1037-1047

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LincRNA-p21 Upregulates Nuclear Orphan Receptor Nr4a2 and Aggravates Myocardial Ischemia/Reperfusion Injury via Targeting MiR-466i-5p.

Zhai X, Liu R, Li J, Wang F, Liu L, Wei S, Bian Y, Pang J, Xue M, Qin D, Wang S, Xu T, Xu F, Cao S, Yuan Q, Chen Y
International heart journal 2022;63(5):1004-1014

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Astragaloside IV - mediated endothelial progenitor cell exosomes promote autophagy and inhibit apoptosis in hyperglycemic damaged endothelial cells via miR-21/PTEN axis.

Xiong W, Huang XL, Li CY, Wang XL, Lan HW, Wang TT, Chen ZL, Yang QP, Hu AL, Xia YF, Zhu FR, Zhou ZZ
Folia histochemica et cytobiologica 2022;60(4):323-334

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Neferine Suppresses Experimental Colitis-Associated Colorectal Cancer by Inhibition of NF-[Formula: see text]B p65 and STAT3.

Zhou Y, Xiang S, Zheng H, Hou Y, Wang Y, Li CC, Wu Q, Shi J, Chen X
The American journal of Chinese medicine 2022;50(5):1387-1400

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Protective Effect of Ginsenosides from Stems and Leaves of Panax ginseng against Scopolamine-Induced Memory Damage via Multiple Molecular Mechanisms.

Wang Y, Zhang JJ, Hou JG, Li X, Liu W, Zhang JT, Zheng SW, Su FY, Li W
The American journal of Chinese medicine 2022;50(4):1113-1131

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Effects of Capsaicin on the Hypoglycemic Regulation of Metformin and Gut Microbiota Profiles in Type 2 Diabetic Rats.

Kang ZQ, Hu JL, Chen MY, Mao Y, Xie LF, Yang N, Liu T, Zhang W, Huang WH
The American journal of Chinese medicine 2022;50(3):839-861

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Proanthocyanidin oligomers extract from hawthorn mediates cell cycle arrest, apoptosis, and lysosome vacuolation on HCT116 cells.

Sun YS, Wang ZW, Gao Z, Zhao W, Thakur K, Zhong Q, Wei ZJ
Current research in food science 2022;5:904-917

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Study on the Protective Effect of Schizandrin B against Acetaminophen-Induced Cytotoxicity in Human Hepatocyte.

Cheng L, Wang T, Gao Z, Wu W, Cao Y, Wang L, Zhang Q
Biological & pharmaceutical bulletin 2022;45(5):596-604

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RING-Finger Protein 6 promotes Drug Resistance in Retinoblastoma via JAK2/STAT3 Signaling Pathway.

Chai Y, Jiao S, Peng X, Gan Q, Chen L, Hu X, Hao L, Zhang S, Tao Q
Pathology oncology research : POR 2022;28:1610273

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Sufentanil Alleviates Sepsis-Induced Myocardial Injury and Stress Response in Rats through the ERK/GSK-3β Signaling Axis.

Zang H, Shao G, Lou Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9630716

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lncRNA IGF2-AS Regulates Nucleotide Metabolism by Mediating HMGA1 to Promote Pyroptosis of Endothelial Progenitor Cells in Sepsis Patients.

Liang G, Zeng M, Gao M, Xing W, Jin X, Wang Q, Deng L, Ou H, He Z
Oxidative medicine and cellular longevity 2022;2022:9369035

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A Network Pharmacology Approach for Uncovering the Antitumor Effects and Potential Mechanisms of the Sijunzi Decoction for the Treatment of Gastric Cancer.

Ding P, Guo Y, Wang C, Chen J, Guo C, Liu H, Shi Q
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9364313

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Qingfei Tongluo Formula Mitigates Mycoplasma pneumoniae Infection via the PERK Signaling Pathway.

Liu X, Wang M, Kan Q, Lin Y, Jiang Z
Disease markers 2022;2022:9340353

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Betaine Inhibits NLRP3 Inflammasome Hyperactivation and Regulates Microglial M1/M2 Phenotypic Differentiation, Thereby Attenuating Lipopolysaccharide-Induced Depression-Like Behavior.

Zhang M, Wang XL, Shi H, Meng LQ, Quan HF, Yan L, Yang HF, Peng XD
Journal of immunology research 2022;2022:9313436

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Hippocampal Mitochondrial Abnormalities Induced the Dendritic Complexity Reduction and Cognitive Decline in a Rat Model of Spinal Cord Injury.

Hu X, Wu L, Wen Y, Liu J, Li H, Zhang Y, Wang Z, Ding J, Zeng Z, Xia H
Oxidative medicine and cellular longevity 2022;2022:9253916

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HSPB8 Overexpression Ameliorates Cognitive Impairment in Diabetic Mice via Inhibiting NLRP3 Inflammation Activation.

Chang Y, Wu Y, Jiang X, Zhu J, Wang C, Ma R, Li G
Oxidative medicine and cellular longevity 2022;2022:9251835

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Electroacupuncture Preconditioning Alleviates Lipopolysaccharides-Induced Acute Lung Injury by Downregulating LC3-II/I and Beclin 1 Expression.

Sun G, Zeng Y, Luo F, Zhang L, Tan J, Tong J, Yang L, Liu D, Liu L, Zhou J
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8997173

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Sequential Treatment with Activin and Hepatocyte Growth Factor Induces FOXM1 to Promote Colorectal Cancer Liver Metastasis.

Peng H, Ye T, Deng L, Yang X, Jiang Z, Guo J
Canadian journal of gastroenterology & hepatology 2022;2022:8996203

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Cell-Dependent Pathogenic Roles of Filamin B in Different Skeletal Malformations.

Wu H, Wang Y, Chen X, Yao Y, Zhao W, Fang L, Sun X, Wang N, Jiang J, Gao L, Zhao J, Xu C
Oxidative medicine and cellular longevity 2022;2022:8956636

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Activation of LRP1 Ameliorates Cerebral Ischemia/Reperfusion Injury and Cognitive Decline by Suppressing Neuroinflammation and Oxidative Stress through TXNIP/NLRP3 Signaling Pathway in Mice.

Yang CJ, Li X, Feng XQ, Chen Y, Feng JG, Jia J, Wei JC, Zhou J
Oxidative medicine and cellular longevity 2022;2022:8729398

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Long Noncoding RNA ENSG00000254693 Promotes Diabetic Kidney Disease via Interacting with HuR.

Yu Q, Lin J, Ma Q, Li Y, Wang Q, Chen H, Liu Y, Liu B
Journal of diabetes research 2022;2022:8679548

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Thioredoxin-Interacting Protein (TXNIP) Knockdown Protects against Sepsis-Induced Brain Injury and Cognitive Decline in Mice by Suppressing Oxidative Stress and Neuroinflammation.

Zhang Y, Xing CJ, Liu X, Li YH, Jia J, Feng JG, Yang CJ, Chen Y, Zhou J
Oxidative medicine and cellular longevity 2022;2022:8645714

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Nr2f2 Overexpression Aggravates Ferroptosis and Mitochondrial Dysfunction by Regulating the PGC-1α Signaling in Diabetes-Induced Heart Failure Mice.

Miao W, Chen M, Chen M, Cui C, Zhu Y, Luo X, Wu B
Mediators of inflammation 2022;2022:8373389

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MiR-205-5p Functions as a Tumor Suppressor in Gastric Cancer Cells through Downregulating FAM84B.

Chen X, Zhang L, Geng J, Chen Z, Cui X
Journal of oncology 2022;2022:8267891

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Downregulated XBP-1 Rescues Cerebral Ischemia/Reperfusion Injury-Induced Pyroptosis via the NLRP3/Caspase-1/GSDMD Axis.

Zhang Y, Yao Z, Xiao Y, Zhang X, Liu J
Mediators of inflammation 2022;2022:8007078

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miR-138-5p Inhibits the Growth and Invasion of Glioma Cells by Regulating WEE1.

Gong J, Tang Z, Yu Z, Deng Z, Liu Y, Ren N, Wang L, He Z
Analytical cellular pathology (Amsterdam) 2022;2022:7809882

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RBM10 Is a Biomarker Associated with Pan-Cancer Prognosis and Immune Infiltration: System Analysis Combined with In Vitro and Vivo Experiments.

Cao Y, Pang L, Jin S
Oxidative medicine and cellular longevity 2022;2022:7654937

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Hepatoblastoma: Derived Exosomal LncRNA NEAT1 Induces BMSCs Differentiation into Tumor-Supporting Myofibroblasts via Modulating the miR-132/MMP9 Axis.

Hu Y, Zai H, Jiang W, Ou Z, Yao Y, Zhu Q
Journal of oncology 2022;2022:7630698

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Celastrol Protects against Cerebral Ischemia/Reperfusion Injury in Mice by Inhibiting Glycolysis through Targeting HIF-1α/PDK1 Axis.

Chen M, Liu M, Luo Y, Cao J, Zeng F, Yang L, Yang J, Tao T, Jiang Y
Oxidative medicine and cellular longevity 2022;2022:7420507

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Protective Effect of Photobiomodulation against Hydrogen Peroxide-Induced Oxidative Damage by Promoting Autophagy through Inhibition of PI3K/AKT/mTOR Pathway in MC3T3-E1 Cells.

Zuo X, Wei X, Ju C, Wang X, Zhang Z, Ma Y, Zhu Z, Li X, Song Z, Luo L, Hu X, Wang Z
Oxidative medicine and cellular longevity 2022;2022:7223353

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Preventive Effects of Ilex Cornuta Aqueous Extract on High-Fat Diet-Induced Fatty Liver of Mice.

Liu M, Jia H, He Y, Huan Y, Kong Z, Xu N, Cao X, Duan Y, Li Z, Yang L, Wei WP, Wang L, Li L
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7183471

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Metabolism-Related Gene TXNRD1 Regulates Inflammation and Oxidative Stress Induced by Cigarette Smoke through the Nrf2/HO-1 Pathway in the Small Airway Epithelium.

Huang Q, Peng M, Gu Y, Wu J, Zhan Y, Deng Z, Chen S, Yang R, Chen J, Xie J
Oxidative medicine and cellular longevity 2022;2022:7067623

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Molecular Mechanisms Underlying the Effects of Bimin Kang Mixture on Allergic Rhinitis: Network Pharmacology and RNA Sequencing Analysis.

Qi LJ, Wang RZ, Gao S, Chen XJ, Zhang X, Zhang YP
BioMed research international 2022;2022:7034078

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Pygo1 Regulates the Behavior of Human Non-Small-Cell Lung Cancer via the Wnt/β-Catenin Pathway.

Wen Y, Li Y, Yang B, Guo X, Lin L, Liang J, Zhang K, Li X, Jiang Z, Wang Y, Li Y, Wu X, Fan X, Li F, Yuan W
Disease markers 2022;2022:6993994

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Targeting Ferroptosis Attenuates Inflammation, Fibrosis, and Mast Cell Activation in Chronic Prostatitis.

Lin D, Zhang M, Luo C, Wei P, Cui K, Chen Z
Journal of immunology research 2022;2022:6833867

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Electroacupuncture at Zusanli Alleviates Sepsis by Regulating the TLR4-MyD88-NF-Kappa B Pathway and Diversity of Intestinal Flora.

Zhan L, Liu H, Zheng J, Meng J, Fu D, Pang L, Ji C
Evidence-based complementary and alternative medicine : eCAM 2022;2022:6706622

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Effects of Electroacupuncture at Different Acupoints on Functional Dyspepsia Rats.

Li YJ, Yang NN, Huang J, Lin LL, Qi LY, Ma SM, Hu CX, Wang Y, Yang JW, Liu CZ
Evidence-based complementary and alternative medicine : eCAM 2022;2022:6548623

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miR-127-5p Targets JAM3 to Regulate Ferroptosis, Proliferation, and Metastasis in Malignant Meningioma Cells.

Zhang J, Liu Z, Dong Y
Disease markers 2022;2022:6423237

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Controlled Hemorrhage Sensitizes Angiotensin II-Elicited Hypertension through Activation of the Brain Renin-Angiotensin System Independently of Endoplasmic Reticulum Stress.

Wu GB, Du HB, Zhai JY, Sun S, Cui JL, Zhang Y, Zhao ZA, Wu JL, Johnson AK, Xue B, Zhao ZG, Zhang GS
Oxidative medicine and cellular longevity 2022;2022:6371048

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The Gut Microbiota Dysbiosis in Preeclampsia Contributed to Trophoblast Cell Proliferation, Invasion, and Migration via lncRNA BC030099/NF-κB Pathway.

Tang R, Xiao G, Jian Y, Yuan Q, Jiang C, Wang W
Mediators of inflammation 2022;2022:6367264

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Correlation Analysis of Umbilical Cord Blood Metabolic Phenotype and Inflammation in Patients with Gestational Diabetes Mellitus Complicated with Overweight and Obesity.

Chen Q, Li W, Deng Y, Li Y, Huang L, Zhao L, Li H
Evidence-based complementary and alternative medicine : eCAM 2022;2022:6072286

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Expression of POT1-AS1 in GC Tissue, Its Effect on Biological Behavior of Gastric Cancer, and Its Significance on Prognosis of Gastric Cancer.

Jiang L, Yang L, Dai Y, Yang G, Pan S
Computational and mathematical methods in medicine 2022;2022:6021994

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Baicalin Alleviates Thrombin-Induced Inflammation in Vascular Smooth Muscle Cells.

Zheng X, Wang P, Jia M, Li Q, Zhang A, Zhou Q
BioMed research international 2022;2022:5799308

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The Traditional Chinese Medicine Formula FTZ Protects against Cardiac Fibrosis by Suppressing the TGFβ1-Smad2/3 Pathway.

Zhang Y, Wang D, Wu K, Shao X, Diao H, Wang Z, Sun M, Huang X, Li Y, Tang X, Yan M, Guo J
Evidence-based complementary and alternative medicine : eCAM 2022;2022:5642307

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Xuesaitong Combined with Dexmedetomidine Improves Cerebral Ischemia-Reperfusion Injury in Rats by Activating Keap1/Nrf2 Signaling and Mitophagy in Hippocampal Tissue.

Han GJ, Min XZ, Ma SS, Ding C, Wang XQ
Oxidative medicine and cellular longevity 2022;2022:5126042

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Quantitative Proteomics Analysis Expands the Roles of Lysine β-Hydroxybutyrylation Pathway in Response to Environmental β-Hydroxybutyrate.

Hou W, Liu G, Ren X, Liu X, He L, Huang H
Oxidative medicine and cellular longevity 2022;2022:4592170

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Cepharanthine Attenuates Early Brain Injury after Subarachnoid Hemorrhage in Mice via Inhibiting 15-Lipoxygenase-1-Mediated Microglia and Endothelial Cell Ferroptosis.

Gao S, Zhou L, Lu J, Fang Y, Wu H, Xu W, Pan Y, Wang J, Wang X, Zhang J, Shao A
Oxidative medicine and cellular longevity 2022;2022:4295208

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Silencing ATF3 Might Delay TBHP-Induced Intervertebral Disc Degeneration by Repressing NPC Ferroptosis, Apoptosis, and ECM Degradation.

Li Y, Pan D, Wang X, Huo Z, Wu X, Li J, Cao J, Xu H, Du L, Xu B
Oxidative medicine and cellular longevity 2022;2022:4235126

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Inhibition of KCTD10 Affects Diabetic Retinopathy Progression by Reducing VEGF and Affecting Angiogenesis.

Feng Y, Wang C, Wang G
Genetics research 2022;2022:4112307

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Preparation and Biocompatibility of Core-Shell Microspheres for Sequential, Sustained Release of BMP-2 and VEGF.

Liu Z, Xu Z, Wang X, Zhang Y, Wu Y, Jiang D, Jia R
BioMed research international 2022;2022:4072975

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Acidic Tumor Microenvironment Promotes Pancreatic Cancer through miR-451a/MEF2D Axis.

Xu J, Li Y, Li Z, Shao W, Song J, Wei J
Journal of oncology 2022;2022:3966386

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The lncRNA KIF9-AS1 Accelerates Hepatocellular Carcinoma Growth by Recruiting DNMT1 to Promote RAI2 DNA Methylation.

Yu Y, Lu X, Yan Y, Wang Y, Meng J, Tian S, Mu J
Journal of oncology 2022;2022:3888798

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Lycopene Improves Bone Quality and Regulates AGE/RAGE/NF-кB Signaling Pathway in High-Fat Diet-Induced Obese Mice.

Xia B, Zhu R, Zhang H, Chen B, Liu Y, Dai X, Ye Z, Zhao D, Mo F, Gao S, Wang XD, Bromme D, Wang L, Wang X, Zhang D
Oxidative medicine and cellular longevity 2022;2022:3697067

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Identification of RPS7 as the Biomarker of Ferroptosis in Acute Kidney Injury.

Zhang H, Liu X, Zhou L, Deng Z, Wang Y
BioMed research international 2022;2022:3667339

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Prognostic Lnc-S100B-2 Affects Cell Apoptosis and Microenvironment of Colorectal Cancer through MLLT10 Signaling.

Yi J, Peng F, Zhao J, Gong X
Journal of oncology 2022;2022:3565118

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Theaflavin-3,3'-Digallate Inhibits Erastin-Induced Chondrocytes Ferroptosis via the Nrf2/GPX4 Signaling Pathway in Osteoarthritis.

Xu C, Ni S, Xu N, Yin G, Yu Y, Zhou B, Zhao G, Wang L, Zhu R, Jiang S, Wang Y
Oxidative medicine and cellular longevity 2022;2022:3531995

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miR-328-5p Induces Human Intervertebral Disc Degeneration by Targeting WWP2.

Yan J, Wu LG, Zhang M, Fang T, Pan W, Zhao JL, Zhou Q
Oxidative medicine and cellular longevity 2022;2022:3511967

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Transcutaneous Electrical Acupoint Stimulation Ameliorates Cognitive Function through PINK1/Parkin Mediated Mitophagy in VD Rats.

Hu Z, Wen T, Hu K, Wang R, Su X, Ouyang W, Zhou J, Wen Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2810794

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Artemisinin and Its Derivate Alleviate Pulmonary Hypertension and Vasoconstriction in Rodent Models.

Bao C, He Q, Wang H, Sun Y, Xu Y, Pan Y, Hu Y, Zheng S, Liang S, Luo A, Nahar T, Chen J, Tang H, Han Y
Oxidative medicine and cellular longevity 2022;2022:2782429

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Therapy-resistant and -sensitive lncRNAs, SNHG1 and UBL7-AS1 promote glioblastoma cell proliferation.

Cao M, Ma R, Li H, Cui J, Zhang C, Zhao J
Oxidative medicine and cellular longevity 2022;2022:2623599

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Rhein Ameliorates Cognitive Impairment in an APP/PS1 Transgenic Mouse Model of Alzheimer's Disease by Relieving Oxidative Stress through Activating the SIRT1/PGC-1α Pathway.

Yin Z, Gao D, Du K, Han C, Liu Y, Wang Y, Gao X
Oxidative medicine and cellular longevity 2022;2022:2524832

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The Pretreatment of Xiaoqinglong Decoction Alleviates Inflammation and Oxidative Damage and Up-Regulates Angiotensin-Converting Enzyme 2 in Lipopolysaccharide-Induced Septic Acute Lung Injury Rats.

Su JC, Cheng C, Wang CY, Zhang Y, He YT, Guo ZW, Liu XY, Liu WM, Zhang YJ, Xu SW, Zhang XY, Liu ZB, Zhang XF
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2421198

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Overexpression of PTPRZ1 Regulates p120/β-Catenin Phosphorylation to Promote Carcinogenesis of Oral Submucous Fibrosis.

Ma L, Shen T, Peng H, Wu J, Wang W, Gao X
Journal of oncology 2022;2022:2352360

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High-Calcium Microenvironment during the Development of Kidney Calculi Can Promote Phenotypic Transformation of NRK-52E Cells by Inhibiting the Expression of Stromal Interaction Molecule-1.

Li LS, Zhu YP, Xia QD, Wang SG, He D
BioMed research international 2022;2022:2350198

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Mitochondrial Targeted Antioxidant SKQ1 Ameliorates Acute Kidney Injury by Inhibiting Ferroptosis.

Song J, Sheng J, Lei J, Gan W, Yang Y
Oxidative medicine and cellular longevity 2022;2022:2223957

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Oleoylethanolamide Alleviates Hepatic Ischemia-Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress-Associated Apoptosis.

Qi S, Yan Q, Wang Z, Liu D, Zhan M, Du J, Chen L
PPAR research 2022;2022:2212996

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Isoschaftoside Reverses Nonalcoholic Fatty Liver Disease via Activating Autophagy In Vivo and In Vitro.

Su Y, Kang Y, Yi J, Lin Q, Zhang C, Lin Z, Yan Z, Qu J, Liu J
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2122563

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Sestrin2 Overexpression Ameliorates Endoplasmic Reticulum Stress-Induced Apoptosis via Inhibiting mTOR Pathway in HepG2 Cells.

Hu H, Luo Z, Liu X, Huang L, Lu X, Ding R, Duan C, He Y
International journal of endocrinology 2022;2022:2009753

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lncRNA GAS5 Sensitizes Breast Cancer Cells to Ionizing Radiation by Inhibiting DNA Repair.

Ma Y, Yu L, Yan W, Qiu L, Zhang J, Jia X
BioMed research international 2022;2022:1987519

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Hugan Buzure Induces Autophagy and Apoptosis in Hepatocellular Carcinoma by Inhibiting PI3K/Akt/mTOR Signaling Pathway.

Meng X, Li M, Qiao M, Li X, Yang J, Hu J
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1618491

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Tuftelin 1 Facilitates Hepatocellular Carcinoma Progression through Regulation of Lipogenesis and Focal Adhesion Maturation.

Zhu L, Zhou KX, Ma MZ, Yao LL, Zhang YL, Li H, Du C, Yang XM
Journal of immunology research 2022;2022:1590717

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Upregulation of Klotho Aggravates Insulin Resistance in Gestational Diabetes Mellitus Trophoblast Cells.

Lin L, Wang X, Zhao W, Chen Y
Genetics research 2022;2022:1500768

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Ginsenoside Rg1 Reduces Oxidative Stress Via Nrf2 Activation to Regulate Age-Related Mesenchymal Stem Cells Fate Switch Between Osteoblasts and Adipocytes.

Hou J, Wang L, Wang C, Ma R, Wang Z, Xiao H, Zeng D, Ling L, Wang Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1411354

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Mitochondrial Transplantation Promotes Remyelination and Long-Term Locomotion Recovery following Cerebral Ischemia.

Chen T, Zhu Y, Jia J, Meng H, Xu C, Xian P, Li Z, Tang Z, Wu Y, Liu Y
Mediators of inflammation 2022;2022:1346343

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PPARγ Alleviates Sepsis-Induced Liver Injury by Inhibiting Hepatocyte Pyroptosis via Inhibition of the ROS/TXNIP/NLRP3 Signaling Pathway.

Li Z, Liu T, Feng Y, Tong Y, Jia Y, Wang C, Cui R, Qu K, Liu C, Zhang J
Oxidative medicine and cellular longevity 2022;2022:1269747

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Paeoniflorin attenuates monocrotaline-induced pulmonary arterial hypertension in rats by suppressing TAK1-MAPK/NF-κB pathways.

Yu M, Wu X, Wang J, He M, Han H, Hu S, Xu J, Yang M, Tan Q, Wang Y, Wang H, Xie W, Kong H
International journal of medical sciences 2022;19(4):681-694

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Upregulation of SQLE Contributes to Poor Survival in Head and Neck Squamous Cell Carcinoma.

Li J, Yang T, Wang Q, Li Y, Wu H, Zhang M, Qi H, Zhang H, Li J
International journal of biological sciences 2022;18(9):3576-3591

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Quantitative proteomics of HFD-induced fatty liver uncovers novel transcription factors of lipid metabolism.

Zhi S, Congcong Z, Zhiling G, Yihan Q, Yijing X, Guanjie L, Fang W, Xuehua S, Hongjie L, Xiaoni K, Yueqiu G
International journal of biological sciences 2022;18(8):3298-3312

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TDG suppresses the migration and invasion of human colon cancer cells via the DNMT3A/TIMP2 axis.

Miao J, Zhao C, Tang K, Xiong X, Wu F, Xue W, Duan B, Zhang H, Jing X, Li W, Sun Y, Hou N, Huang C
International journal of biological sciences 2022;18(6):2527-2539

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Mannan-Binding Lectin Deficiency Limits Inflammation-induced Myeloid-Derived Suppressor Cells Expansion via Modulating Tumor Necrosis Factor Alpha-triggered Apoptosis.

Dong L, Jiang H, Chen K, Xie J, An Q, Deng F, Sun Z, Liu Y, Zhou J, Zhang L, Lu X, Wang M, Chen Z, Zou X, Zuo D
International journal of biological sciences 2022;18(4):1580-1593

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Cancer-associated adipocytes promote the invasion and metastasis in breast cancer through LIF/CXCLs positive feedback loop.

Zhou C, He X, Tong C, Li H, Xie C, Wu Y, Wang L, Yan X, Luo D, Tang Y, Cheng Z, Xiong X
International journal of biological sciences 2022;18(4):1363-1380

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Hypoxic pancreatic cancer derived exosomal miR-30b-5p promotes tumor angiogenesis by inhibiting GJA1 expression.

Chen K, Wang Q, Liu X, Wang F, Yang Y, Tian X
International journal of biological sciences 2022;18(3):1220-1237

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Mir-484 contributes to diminished ovarian reserve by regulating granulosa cell function via YAP1-mediated mitochondrial function and apoptosis.

Li H, Wang X, Mu H, Mei Q, Liu Y, Min Z, Zhang L, Su P, Xiang W
International journal of biological sciences 2022;18(3):1008-1021

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Lactylation of PKM2 Suppresses Inflammatory Metabolic Adaptation in Pro-inflammatory Macrophages.

Wang J, Yang P, Yu T, Gao M, Liu D, Zhang J, Lu C, Chen X, Zhang X, Liu Y
International journal of biological sciences 2022;18(16):6210-6225

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P2RY13 Exacerbates Intestinal Inflammation by Damaging the Intestinal Mucosal Barrier via Activating IL-6/STAT3 Pathway.

Wu X, Wei S, Chen M, Li J, Wei Y, Zhang J, Dong W
International journal of biological sciences 2022;18(13):5056-5069

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A Novel ER Stress Mediator TMTC3 Promotes Squamous Cell Carcinoma Progression by Activating GRP78/PERK Signaling Pathway.

Yuan H, Zhao Z, Guo Z, Ma L, Han J, Song Y
International journal of biological sciences 2022;18(13):4853-4868

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The m6A-induced lncRNA CASC8 promotes proliferation and chemoresistance via upregulation of hnRNPL in esophageal squamous cell carcinoma.

Wu Q, Zhang H, Yang D, Min Q, Wang Y, Zhang W, Zhan Q
International journal of biological sciences 2022;18(13):4824-4836

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Deacetylation of Glutaminase by HDAC4 contributes to Lung Cancer Tumorigenesis.

Wang T, Lu Z, Han T, Wang Y, Gan M, Wang JB
International journal of biological sciences 2022;18(11):4452-4465

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RASAL2 mediated the enhancement of YAP1/TIAM1 signaling promotes malignant phenotypes of pancreatic ductal adenocarcinoma.

Yue Y, Wu K, Qian W, Zhu Z, Zhang S, Zhang W, Zhang W, Wu S, Li L, Wu Z, Ma Q, Xie K, Wang Z
International journal of biological sciences 2022;18(10):4245-4259

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Mechanosensitive Piezo1 is crucial for periosteal stem cell-mediated fracture healing.

Liu Y, Tian H, Hu Y, Cao Y, Song H, Lan S, Dai Z, Chen W, Zhang Y, Shao Z, Liu Y, Tong W
International journal of biological sciences 2022;18(10):3961-3980

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Enhanced Intracellular Reactive Oxygen Species by Photodynamic Therapy Effectively Promotes Chemoresistant Cell Death.

Xu X, Wang C, Zhang P, Gao X, Guan W, Wang F, Li X, Yuan J, Dou H, Xu G
International journal of biological sciences 2022;18(1):374-385

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Supplementation with dietary omega-3 PUFA mitigates fetal brain inflammation and mitochondrial damage caused by high doses of sodium nitrite in maternal rats.

Sun J, Zhang W
PloS one 2022;17(3):e0266084

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LncRNA LINC01857 reduces metastasis and angiogenesis in breast cancer cells via regulating miR-2052/CENPQ axis.

Qian W, Yang L, Ni Y, Yin F, Qin L, Yang Y
Open medicine (Warsaw, Poland) 2022;17(1):1357-1367

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Long non-coding RNA NEAT1 promotes angiogenesis in hepatoma carcinoma via the miR-125a-5p/VEGF pathway.

Guo J, Yuan Q, Fang Y, Liao J, Zhang Z
Open life sciences 2022;17(1):1229-1239

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NCOA4-Mediated Ferroptosis in Bronchial Epithelial Cells Promotes Macrophage M2 Polarization in COPD Emphysema.

Liu J, Zhang Z, Yang Y, Di T, Wu Y, Bian T
International journal of chronic obstructive pulmonary disease 2022;17:667-681

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Study on the Local Anti-Osteoporosis Effect of Polaprezinc-Loaded Antioxidant Electrospun Membrane.

Gao X, Al-Baadani MA, Wu M, Tong N, Shen X, Ding X, Liu J
International journal of nanomedicine 2022;17:17-29

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Pseudoephedrine Nanoparticles Alleviate Adriamycin-Induced Reproductive Toxicity Through the GnRhR Signaling Pathway.

Fu Y, Yuan P, Zheng Y, Wei Y, Gao L, Ruan Y, Chen Y, Li P, Feng W, Zheng X
International journal of nanomedicine 2022;17:1549-1566

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Microglial activation in the motor cortex mediated NLRP3-related neuroinflammation and neuronal damage following spinal cord injury.

Hu X, Zhang Y, Wang L, Ding J, Li M, Li H, Wu L, Zeng Z, Xia H
Frontiers in cellular neuroscience 2022;16:956079

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The Role of Microglia/Macrophages Activation and TLR4/NF-κB/MAPK Pathway in Distraction Spinal Cord Injury-Induced Inflammation.

Liang W, Han B, Hai Y, Liu Y, Liu X, Yang J, Sun D, Yin P
Frontiers in cellular neuroscience 2022;16:926453

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Ursolic Acid Ameliorates Spinal Cord Injury in Mice by Regulating Gut Microbiota and Metabolic Changes.

Rong ZJ, Cai HH, Wang H, Liu GH, Zhang ZW, Chen M, Huang YL
Frontiers in cellular neuroscience 2022;16:872935

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MicroRNA-582-5p Contributes to the Maintenance of Neural Stem Cells Through Inhibiting Secretory Protein FAM19A1.

Zhang YF, Li XX, Cao XL, Ji CC, Gao XY, Gao D, Han H, Yu F, Zheng MH
Frontiers in cellular neuroscience 2022;16:866020

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Meningitic Escherichia coli-Induced Interleukin-17A Facilitates Blood-Brain Barrier Disruption via Inhibiting Proteinase 3/Protease-Activated Receptor 2 Axis.

Xu B, Chen J, Fu J, Yang R, Yang B, Huo D, Tan C, Chen H, Wang X
Frontiers in cellular neuroscience 2022;16:814867

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Anomalous Levels of CD47/Signal Regulatory Protein Alpha in the Hippocampus Lead to Excess Microglial Engulfment in Mouse Model of Perioperative Neurocognitive Disorders.

Shui M, Sun Y, Lin D, Xue Z, Liu J, Wu A, Wei C
Frontiers in neuroscience 2022;16:788675

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Genetic Inhibition of Plppr5 Aggravates Hypoxic-Ischemie-Induced Cortical Damage and Excitotoxic Phenotype.

Sun Y, Jin MF, Li L, Liu Y, Wang D, Ni H
Frontiers in neuroscience 2022;16:751489

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Anti-Inflammatory Effects and Molecular Mechanisms of Shenmai Injection in Treating Acute Pancreatitis: Network Pharmacology Analysis and Experimental Verification.

He Y, Hu C, Liu S, Xu M, Liang G, Du D, Liu T, Cai F, Chen Z, Tan Q, Deng L, Xia Q
Drug design, development and therapy 2022;16:2479-2495

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The m6A RNA Modification Quantity and the Prognostic Effect of Reader YTHDC2 in Colorectal Cancer.

Liu T, Tang W, Chen Y, Liu Y, Xu D, Jiang Y, Zhou S, Qin X, Ren L, Chang W, Xu J
Clinical Medicine Insights. Oncology 2022;16:11795549221104441

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Excitatory and Inhibitory Synaptic Imbalance Caused by Brain-Derived Neurotrophic Factor Deficits During Development in a Valproic Acid Mouse Model of Autism.

Qi C, Chen A, Mao H, Hu E, Ge J, Ma G, Ren K, Xue Q, Wang W, Wu S
Frontiers in molecular neuroscience 2022;15:860275

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NF-κB and AP-1 are required for the lipopolysaccharide-induced expression of MCP-1, CXCL1, and Cx43 in cultured rat dorsal spinal cord astrocytes.

Lu Y, Li B, Xu A, Liang X, Xu T, Jin H, Xie Y, Wang R, Liu X, Gao X, Han Y, Zeng J
Frontiers in molecular neuroscience 2022;15:859558

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FGF15 Protects Septic Mice by Inhibiting Inflammation and Modulating Treg Responses.

Li X, Zhu Z, Xia Z, Xu B
Journal of inflammation research 2022;15:6187-6197

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Engeletin Alleviates the Inflammation and Apoptosis in Intervertebral Disc Degeneration via Inhibiting the NF-κB and MAPK Pathways.

Li B, Yang X, Zhang P, Guo J, Rong K, Wang X, Cao X, Zhou T, Zhao J
Journal of inflammation research 2022;15:5767-5783

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Chitosan/Sodium Alginate/Velvet Antler Blood Peptides Hydrogel Promotes Diabetic Wound Healing via Regulating Angiogenesis, Inflammatory Response and Skin Flora.

Hao M, Ding C, Sun S, Peng X, Liu W
Journal of inflammation research 2022;15:4921-4938

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Alpha-Momorcharin Inhibits Proinflammatory Cytokine Expression by M1 Macrophages but Not Anti-Inflammatory Cytokine Expression by M2 Macrophages.

Peng K, Deng N, Meng Y, He Q, Meng H, Luo T, Wei Y, Kang Y, Zhou X, Shen F
Journal of inflammation research 2022;15:4853-4872

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MULT1-Encoding DNA Alleviates Schistosomiasis-Associated Hepatic Fibrosis via Modulating Cellular Immune Response.

Yang L, Sun L, Cao Y, Wang Q, Song A, Zhu R, Liu W, Lu S
Journal of inflammation research 2022;15:4027-4045

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miR-17-5p Promotes Glucose Uptake of HTR8/SVneo Trophoblast Cells by Inhibiting TXNIP/NLRP3 Inflammasome Pathway.

Jiang Y, Wei L, Zhang H, Chen Y, Gao P, Zhang J, Zhou X, Zhu S, Du Y, Fang C, Li J, Feng L, He M, Wang S, Yu J
Diabetes, metabolic syndrome and obesity : targets and therapy 2022;15:3361-3374

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Effect of Azelaic Acid on Psoriasis Progression Investigated Based on Phosphatidylinositol 3-Kinase (PI3K)/Protein Kinase B (AKT) Signaling Pathway.

Li L, Lu H, Zhang Y, Li Q, Shi S, Liu Y
Clinical, cosmetic and investigational dermatology 2022;15:2523-2534

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Identification of Biomarkers Related to Regulatory T Cell Infiltration in Oral Squamous Cell Carcinoma Based on Integrated Bioinformatics Analysis.

Wang C, Chen Z, Yang X, Zhang W, Zhou J, Zhang H, Ding X, Ye J, Wu H, Wu Y, Zheng Y, Song X
International journal of general medicine 2022;15:2361-2376

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Mannan-Binding Lectin Regulates the Th17/Treg Axis Through JAK/STAT and TGF-β/SMAD Signaling Against Candida albicans Infection.

Wang F, Yang Y, Li Z, Wang Y, Zhang Z, Zhang W, Mu Y, Yang J, Yu L, Wang M
Journal of inflammation research 2022;15:1797-1810

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Shortening of the KHDRBS1 3'UTR by alternative cleavage and polyadenylation alters miRNA-mediated regulation and promotes gastric cancer progression.

Yu X, Kang W, Zhang J, Chen C, Liu Y
American journal of translational research 2022;14(9):6574-6585

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Arsenic exposure increases susceptibility to Ptpn11-induced malignancy in mouse embryonic fibroblasts through mitochondrial hypermetabolism.

Yang F, Tan Z, Dai Y, Wang X, Huang Z, Kan C, Wang S
American journal of translational research 2022;14(7):4591-4605

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TM9SF4 Is a Crucial Regulator of Inflammation and ER Stress in Inflammatory Bowel Disease.

Xie M, Mak JWY, Yu H, Cheng CTY, Chan HCH, Chan TT, Lau LHS, Wong MTL, Ko WH, Jiang L, Yao X
Cellular and molecular gastroenterology and hepatology 2022;14(2):245-270

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GDF15 negatively regulates RGS16 to impair hepatic lipid metabolism in male mice offspring conceived by in vitro fertilization.

Liu J, Zhu Y, Zhu D, Shi Y, Lu L, Li W, Li L, Zhou X, Zhang P, Yang H, Li M, Wang B, Sun M
American journal of translational research 2022;14(10):7535-7551

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The CEL-HYB1 Hybrid Allele Promotes Digestive Enzyme Misfolding and Pancreatitis in Mice.

Mao XT, Zou WB, Cao Y, Wang YC, Deng SJ, Cooper DN, Férec C, Li ZS, Chen JM, Liao Z
Cellular and molecular gastroenterology and hepatology 2022;14(1):55-74

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Presenilin Deficiency Increases Susceptibility to Oxidative Damage in Fibroblasts.

Zou K, Islam S, Sun Y, Gao Y, Nakamura T, Komano H, Tomita T, Michikawa M
Frontiers in aging neuroscience 2022;14:902525

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Role of BDNF/ProBDNF Imbalance in Postoperative Cognitive Dysfunction by Modulating Synaptic Plasticity in Aged Mice.

Xue Z, Shui M, Lin X, Sun Y, Liu J, Wei C, Wu A, Li T
Frontiers in aging neuroscience 2022;14:780972

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Identification of Key Genes and FUNCTIONAL Pathway in Radioresistance of Non-Small Cell Lung Cancer.

Li S, Feng J, Weng H, Zhao F, Cui G, Fu W, Lin X, Hu H
Cancer management and research 2022;14:2871-2884

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AKAP9 Upregulation Predicts Unfavorable Prognosis in Pediatric Acute Myeloid Leukemia and Promotes Stemness Properties via the Wnt/β-Catenin Pathway.

Wu S, Shen D, Zhao L
Cancer management and research 2022;14:157-167

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Circular RNA circASPM promotes the progression of glioblastoma by acting as a competing endogenous RNA to regulate miR-130b-3p/E2F1 axis.

Hou D, Wang Z, Li H, Liu J, Liu Y, Jiang Y, Lou M
Journal of Cancer 2022;13(5):1664-1678

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Targeting HNRNPM Inhibits Cancer Stemness and Enhances Antitumor Immunity in Wnt-activated Hepatocellular Carcinoma.

Zhu GQ, Wang Y, Wang B, Liu WR, Dong SS, Chen EB, Cai JL, Wan JL, Du JX, Song LN, Chen SP, Yu L, Zhou ZJ, Wang Z, Zhou J, Shi YH, Fan J, Dai Z
Cellular and molecular gastroenterology and hepatology 2022;13(5):1413-1447

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Loss of SPTBN1 Suppresses Autophagy Via SETD7-mediated YAP Methylation in Hepatocellular Carcinoma Initiation and Development.

Chen S, Wu H, Wang Z, Jia M, Guo J, Jin J, Li X, Meng D, Lin L, He AR, Zhou P, Zhi X
Cellular and molecular gastroenterology and hepatology 2022;13(3):949-973.e7

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Epigenetic modifications inhibit the expression of MARVELD1 and in turn tumorigenesis by regulating the Wnt/β-catenin pathway in pan-cancer.

Zhang J, Li Q, Sun Q, Wang B, Cui Y, Lou C, Yao Y, Zhang Y
Journal of Cancer 2022;13(1):225-242

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Akkermansia muciniphila administration exacerbated the development of colitis-associated colorectal cancer in mice.

Wang F, Cai K, Xiao Q, He L, Xie L, Liu Z
Journal of Cancer 2022;13(1):124-133

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Temporally integrated transcriptome analysis reveals ASFV pathology and host response dynamics.

Lv L, Zhang T, Jia H, Zhang Y, Ahsan A, Zhao X, Chen T, Shen Z, Shen N
Frontiers in immunology 2022;13:995998

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Photobiomodulation promotes repair following spinal cord injury by restoring neuronal mitochondrial bioenergetics via AMPK/PGC-1α/TFAM pathway.

Zhu Z, Wang X, Song Z, Zuo X, Ma Y, Zhang Z, Ju C, Liang Z, Li K, Hu X, Wang Z
Frontiers in pharmacology 2022;13:991421

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Connective tissue disease-related interstitial lung disease is alleviated by tripterine through inhibition of the PI3K/Akt, apoptosis, and TNF-α signalling pathways.

Zhu W, Wang Y, Liu C, Wu Y, Li Y, Wang Y
Frontiers in pharmacology 2022;13:990760

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Herpes simplex virus type 2 inhibits TNF-α-induced NF-κB activation through viral protein ICP22-mediated interaction with p65.

Hu H, Fu M, Li C, Zhang B, Li Y, Hu Q, Zhang M
Frontiers in immunology 2022;13:983502

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MiR-146b-5p/TRAF6 axis is essential for Ginkgo biloba L. extract GBE to attenuate LPS-induced neuroinflammation.

Liu M, Peng Y, Che Y, Zhou M, Bai Y, Tang W, Huang S, Zhang B, Deng S, Wang C, Yu Z
Frontiers in pharmacology 2022;13:978587

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Anti-inflammatory, antioxidant and anti-virulence roles of atractylodin in attenuating Listeria monocytogenes infection.

Xu L, Zhou Y, Xu J, Xu X, Lu G, Lv Q, Wei L, Deng X, Shen X, Feng H, Wang J
Frontiers in immunology 2022;13:977051

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Annexin A2 regulates Mycoplasma bovis adhesion and invasion to embryo bovine lung cells affecting molecular expression essential to inflammatory response.

Zhang H, Lu D, Zhang Y, Zhao G, Raheem A, Chen Y, Chen X, Hu C, Chen H, Yang L, Guo A
Frontiers in immunology 2022;13:974006

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Cannabidiol prevents methamphetamine-induced neurotoxicity by modulating dopamine receptor D1-mediated calcium-dependent phosphorylation of methyl-CpG-binding protein 2.

Shen B, Zhang R, Yang G, Peng Y, Nie Q, Yu H, Dong W, Chen B, Song C, Tian Y, Qin L, Shu J, Hong S, Li L
Frontiers in pharmacology 2022;13:972828

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Calycosin attenuates renal ischemia/reperfusion injury by suppressing NF-κB mediated inflammation via PPARγ/EGR1 pathway.

Zhang N, Guan C, Liu Z, Li C, Yang C, Xu L, Niu M, Zhao L, Zhou B, Che L, Wang Y, Xu Y
Frontiers in pharmacology 2022;13:970616

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Coxsackievirus B3 infection induces glycolysis to facilitate viral replication.

Qian Y, Yang Y, Qing W, Li C, Kong M, Kang Z, Zuo Y, Wu J, Yu M, Yang Z
Frontiers in microbiology 2022;13:962766

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Enterovirus A71 utilizes host cell lipid β-oxidation to promote its replication.

Yang X, Chen J, Lu Z, Huang S, Zhang S, Cai J, Zhou Y, Cao G, Yu J, Qin Z, Zhao W, Zhang B, Zhu L
Frontiers in microbiology 2022;13:961942

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Creatinine accelerates APAP-induced liver damage by increasing oxidative stress through ROS/JNK signaling pathway.

Liu F, Liu Y, Peng Q, Wang G, Tan Q, Ou Z, Xu Q, Liu C, Zuo D, Zhao J
Frontiers in pharmacology 2022;13:959497

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Vaccarin alleviates endothelial inflammatory injury in diabetes by mediating miR-570-3p/HDAC1 pathway.

Li T, Yu X, Zhu X, Wen Y, Zhu M, Cai W, Hou B, Xu F, Qiu L
Frontiers in pharmacology 2022;13:956247

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SMO mutation predicts the effect of immune checkpoint inhibitor: From NSCLC to multiple cancers.

Ji W, Niu X, Yu Y, Li Z, Gu L, Lu S
Frontiers in immunology 2022;13:955800

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Chrysophanol-8-O-glucoside protects mice against acute liver injury by inhibiting autophagy in hepatic stellate cells and inflammatory response in liver-resident macrophages.

Wang T, Lu Z, Qu XH, Xiong ZY, Wu YT, Luo Y, Zhang ZY, Han XJ, Xie CF
Frontiers in pharmacology 2022;13:951521

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Therapeutic effects and mechanisms of N-(9,10-anthraquinone-2-ylcarbonyl) xanthine oxidase inhibitors on hyperuricemia.

Gao T, Xu J, Xiao Y, Li J, Hu W, Su X, Shen X, Yu W, Chen Z, Huang B, Li H, Wang X
Frontiers in pharmacology 2022;13:950699

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Network pharmacology and experimental analysis to reveal the mechanism of Dan-Shen-Yin against endothelial to mesenchymal transition in atherosclerosis.

Hong M, Wu Y, Zhang H, Gu J, Chen J, Guan Y, Qin X, Li Y, Cao J
Frontiers in pharmacology 2022;13:946193

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(±)-5-bromo-2-(5-fluoro-1-hydroxyamyl) Benzoate Protects Against Oxidative Stress Injury in PC12 Cells Exposed to H(2)O(2) Through Activation of Nrf2 Pathway.

Qi S, Zhang X, Fu Z, Pi A, Shi F, Fan Y, Zhang J, Xiao T, Shang D, Lin M, Gao N, Chang J, Gao Y
Frontiers in pharmacology 2022;13:943111

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Mycoplasma bovis inhibits autophagy in bovine mammary epithelial cells via a PTEN/PI3K-Akt-mTOR-dependent pathway.

Xu M, Liu Y, Mayinuer T, Lin Y, Wang Y, Gao J, Wang D, Kastelic JP, Han B
Frontiers in microbiology 2022;13:935547

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Identification of the effect and mechanism of Yiyi Fuzi Baijiang powder against colorectal cancer using network pharmacology and experimental validation.

Xiang B, Geng R, Zhang Z, Ji X, Zou J, Chen L, Liu J
Frontiers in pharmacology 2022;13:929836

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PM2.5 Synergizes With Pseudomonas aeruginosa to Suppress Alveolar Macrophage Function in Mice Through the mTOR Pathway.

Zhang J, Liu C, Zhao G, Li M, Ma D, Meng Q, Tang W, Huang Q, Shi P, Li Y, Jiang L, Yu X, Zhu H, Chen G, Zhang X
Frontiers in pharmacology 2022;13:924242

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Transcriptomic Analysis of Dysregulated Genes of the nDNA-mtDNA Axis in a Mouse Model of Dilated Cardiomyopathy.

Ziemann M, Wu W, Deng XL, Du XJ
Frontiers in genetics 2022;13:921610

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Allyl methyl trisulfide protected against LPS-induced acute lung injury in mice via inhibition of the NF-κB and MAPK pathways.

Wang S, Liu J, Dong J, Fan Z, Wang F, Wu P, Li X, Kou R, Chen F
Frontiers in pharmacology 2022;13:919898

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Role of complement C1q/C3-CR3 signaling in brain injury after experimental intracerebral hemorrhage and the effect of minocycline treatment.

Zheng Y, Fan L, Xia S, Yang Q, Zhang Z, Chen H, Zeng H, Fu X, Peng Y, Xu C, Yu K, Liu F, Cao S
Frontiers in immunology 2022;13:919444

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Reduced Immunity Regulator MAVS Contributes to Non-Hypertrophic Cardiac Dysfunction by Disturbing Energy Metabolism and Mitochondrial Homeostasis.

Wang Q, Sun Z, Cao S, Lin X, Wu M, Li Y, Yin J, Zhou W, Huang S, Zhang A, Zhang Y, Xia W, Jia Z
Frontiers in immunology 2022;13:919038

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Yi-Shen-Hua-Shi Granule Alleviates Adriamycin-Induced Glomerular Fibrosis by Suppressing the BMP2/Smad Signaling Pathway.

Tan Z, Si Y, Yu Y, Ding J, Huang L, Xu Y, Zhang H, Lu Y, Wang C, Yu B, Yuan L
Frontiers in pharmacology 2022;13:917428

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ATP-citrate lyase inhibitor improves ectopic lipid accumulation in the kidney in a db/db mouse model.

Zhan Z, Li A, Zhang W, Wu X, He J, Li Z, Li Y, Sun J, Zhang H
Frontiers in endocrinology 2022;13:914865

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Berberrubine, a Main Metabolite of Berberine, Alleviates Non-Alcoholic Fatty Liver Disease via Modulating Glucose and Lipid Metabolism and Restoring Gut Microbiota.

Yang S, Cao S, Li C, Zhang J, Liu C, Qiu F, Kang N
Frontiers in pharmacology 2022;13:913378

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Cisplatin-Induced Anorexia and Pica Behavior in Rats Enhanced by Chronic Stress Pretreatment.

Guo Z, Duan J, Chen Y, Cai W, Yang C, Yang Z, Liu X, Xu F
Frontiers in pharmacology 2022;13:913124

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Curcumol Suppresses CCF-Mediated Hepatocyte Senescence Through Blocking LC3B-Lamin B1 Interaction in Alcoholic Fatty Liver Disease.

Qi X, Zheng S, Ma M, Lian N, Wang H, Chen L, Song A, Lu C, Zheng S, Jin H
Frontiers in pharmacology 2022;13:912825

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Empagliflozin Attenuates Obesity-Related Kidney Dysfunction and NLRP3 Inflammasome Activity Through the HO-1-Adiponectin Axis.

Ye T, Zhang J, Wu D, Shi J, Kuang Z, Ma Y, Xu Q, Chen B, Kan C, Sun X, Han F
Frontiers in endocrinology 2022;13:907984

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Total extract of Abelmoschus manihot L. alleviates uric acid-induced renal tubular epithelial injury via inhibition of caspase-8/caspase-3/NLRP3/GSDME signaling.

Ding Z, Zhao J, Wang X, Li W, Chen C, Yong C, Zhu Y, Tian F, Liu L, Yu M, Zhou E, Gu L, Yao C, Gao K
Frontiers in pharmacology 2022;13:907980

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Furfural Produces Dose-Dependent Attenuating Effects on Ethanol-Induced Toxicity in the Liver.

Cheng Z, Luo X, Zhu Z, Huang Y, Yan X
Frontiers in pharmacology 2022;13:906933

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Ninjinyoeito improves social behavior disorder in neuropeptide Y deficient zebrafish.

Kawabe M, Nishida T, Horita C, Ikeda A, Takahashi R, Inui A, Shiozaki K
Frontiers in pharmacology 2022;13:905711

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A Mechanistic Exploratory Study on the Therapeutic Efficacy of Astragaloside IV Against Diabetic Retinopathy Revealed by Network Pharmacology.

Zhao ZH, Xu M, Fu C, Huang Y, Wang TH, Zuo ZF, Liu XZ
Frontiers in pharmacology 2022;13:903485

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Csf2ra deletion attenuates acute lung injuries induced by intratracheal inoculation of aerosolized ricin in mice.

Zong F, Li S, Wang Y, Xiao N, Deng M, Zhang Z, Su D, Gao B, Zhou D, Hu L, Yang H
Frontiers in immunology 2022;13:900755

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USP7 Promotes deubiquitination and stabilization of MyD88 to enhance immune responses.

Zhang N, Wang F, Zhang G, Zhang Q, Liu Y, Wang Q, Elsharkawy MS, Zheng M, Wen J, Zhao G, Li Q
Frontiers in immunology 2022;13:900243

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Transcriptomics and Network Pharmacology Reveal the Protective Effect of Chaiqin Chengqi Decoction on Obesity-Related Alcohol-Induced Acute Pancreatitis via Oxidative Stress and PI3K/Akt Signaling Pathway.

Yang X, Yao L, Yuan M, Zhang X, Jakubowska MA, Ferdek PE, Dai L, Yang J, Jin T, Deng L, Fu X, Du D, Liu T, Criddle DN, Sutton R, Huang W, Xia Q
Frontiers in pharmacology 2022;13:896523

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Astragalus-Scorpion Drug Pair Inhibits the Development of Prostate Cancer by Regulating GDPD4-2/PI3K/AKT/mTOR Pathway and Autophagy.

You X, Wu Y, Li Q, Sheng W, Zhou Q, Fu W
Frontiers in pharmacology 2022;13:895696

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Natural Compound Library Screening Identifies Oroxin A for the Treatment of Myocardial Ischemia/Reperfusion Injury.

Cheng X, Huang T, Wang C, Hao S, Shu L, Wang S, Cheng G, Zhang Q, Huang J, Chen C
Frontiers in pharmacology 2022;13:894899

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EGFR Activation Impairs Antiviral Activity of Interferon Signaling in Brain Microvascular Endothelial Cells During Japanese Encephalitis Virus Infection.

Zhang YG, Chen HW, Zhang HX, Wang K, Su J, Chen YR, Wang XR, Fu ZF, Cui M
Frontiers in microbiology 2022;13:894356

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A ROCK1 Inhibitior Fasudil Alleviates Cardiomyocyte Apoptosis in Diabetic Cardiomyopathy by Inhibiting Mitochondrial Fission in a Type 2 Diabetes Mouse Model.

Fan X, Li X, Liu H, Xu F, Ji X, Chen Y, Li C
Frontiers in pharmacology 2022;13:892643

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Oridonin Delays Aging Through the AKT Signaling Pathway.

An Y, Zhu J, Wang X, Sun X, Luo C, Zhang Y, Ye Y, Li X, Abulizi A, Huang Z, Zhang H, Yang B, Xie Z
Frontiers in pharmacology 2022;13:888247

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TIPE2 May Target the Nrf2/HO-1 Pathway to Inhibit M1 Macrophage-Related Neutrophilic Inflammation in Asthma.

Shi B, Hao Y, Li W, Dong H, Xu M, Gao P
Frontiers in immunology 2022;13:883885

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Engineered Exosomes-Mediated Transfer of hsa-miR-320a Overcomes Chemoresistance in Cervical Cancer Cells via Targeting MCL1.

Zhou J, Wang Y, Zhang L, Chen Q, Zhu X, Jiang P, Jiang N, Zhao W, Li B
Frontiers in pharmacology 2022;13:883445

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Pan-Cancer Analysis of the Immunological Role of PDIA5: A Potential Target for Immunotherapy.

Chen Y, He J, Chen R, Wang Z, Dai Z, Liang X, Wu W, Luo P, Zhang J, Peng Y, Zhang N, Liu Z, Zhang L, Zhang H, Cheng Q
Frontiers in immunology 2022;13:881722

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Host MKRN1-Mediated Mycobacterial PPE Protein Ubiquitination Suppresses Innate Immune Response.

Dou Y, Xie Y, Zhang L, Liu S, Xu D, Wei Y, Li Y, Zhang XL
Frontiers in immunology 2022;13:880315

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Hepatotoxicity of the Major Anthraquinones Derived From Polygoni Multiflori Radix Based on Bile Acid Homeostasis.

Kang L, Li D, Jiang X, Zhang Y, Pan M, Hu Y, Si L, Zhang Y, Huang J
Frontiers in pharmacology 2022;13:878817

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Clinical significance of SPOCK2 expression signature for high-grade serous ovarian cancer patients.

Jiao M, Sun W, Li L, Li C, Zhou J, Li Q, Duan L
Frontiers in genetics 2022;13:878123

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Baohuoside I Inhibits Osteoclastogenesis and Protects Against Ovariectomy-Induced Bone Loss.

Ma M, Fan AY, Liu Z, Yang LQ, Huang JM, Pang ZY, Yin F
Frontiers in pharmacology 2022;13:874952

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Ginsenoside Rb1 Ameliorated Bavachin-Induced Renal Fibrosis via Suppressing Bip/eIF2α/CHOP Signaling-Mediated EMT.

Ni YH, Deng HF, Zhou L, Huang CS, Wang NN, Yue LX, Li GF, Yu HJ, Zhou W, Gao Y
Frontiers in pharmacology 2022;13:872474

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Effects of Pereskia aculeate Miller Petroleum Ether Extract on Complete Freund's Adjuvant-Induced Rheumatoid Arthritis in Rats and its Potential Molecular Mechanisms.

Chen Y, Liu K, Qin Y, Chen S, Guan G, Huang Y, Chen Y, Mo Z
Frontiers in pharmacology 2022;13:869810

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Knockdown of NRSF Alleviates Ischemic Brain Injury and Microvasculature Defects in Diabetic MCAO Mice.

He CF, Xue WJ, Xu XD, Wang JT, Wang XR, Feng Y, Zhou HG, Guo JC
Frontiers in neurology 2022;13:869220

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Vitamin D3 Suppresses Human Cytomegalovirus-Induced Vascular Endothelial Apoptosis via Rectification of Paradoxical m6A Modification of Mitochondrial Calcium Uniporter mRNA, Which Is Regulated by METTL3 and YTHDF3.

Zhu W, Zhang H, Wang S
Frontiers in microbiology 2022;13:861734

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Single Cell Dissection of Epithelial-Immune Cellular Interplay in Acute Kidney Injury Microenvironment.

Zhang M, Wu L, Deng Y, Peng F, Wang T, Zhao Y, Chen P, Liu J, Cai G, Wang L, Wu J, Chen X
Frontiers in immunology 2022;13:857025

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AQP2 Promotes Astrocyte Activation by Modulating the TLR4/NFκB-p65 Pathway Following Intracerebral Hemorrhage.

Deng S, Chen X, Lei Q, Lu W
Frontiers in immunology 2022;13:847360

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The Construction and Immunogenicity Analyses of Recombinant Pseudorabies Virus With NADC30-Like Porcine Reproductive and Respiratory Syndrome Virus-Like Particles Co-expression.

Zhao J, Zhu L, Xu L, Li F, Deng H, Huang Y, Gu S, Sun X, Zhou Y, Xu Z
Frontiers in microbiology 2022;13:846079

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Saikosaponin D Inhibited IL-1β Induced ATDC 5 Chondrocytes Apoptosis In Vitro and Delayed Articular Cartilage Degeneration in OA Model Mice In Vivo.

Wu X, Zhao K, Fang X, Lu F, Cheng P, Song X, Zhang W, Yao C, Zhu J, Chen H
Frontiers in pharmacology 2022;13:845959

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Network Pharmacology-Based Strategy to Identify the Pharmacological Mechanisms of Pulsatilla Decoction against Crohn's Disease.

Liu J, Zhang L, Wang Z, Chen S, Feng S, He Y, Zhang S
Frontiers in pharmacology 2022;13:844685

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Dan-Shen-Yin Granules Prevent Hypoxia-Induced Pulmonary Hypertension via STAT3/HIF-1α/VEGF and FAK/AKT Signaling Pathways.

Wang RR, Yuan TY, Chen D, Chen YC, Sun SC, Wang SB, Kong LL, Fang LH, Du GH
Frontiers in pharmacology 2022;13:844400

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Exogenous Linoleic Acid Intervention Alters Hepatic Glucose Metabolism in an Avian Embryo Model.

Zhang X, Wu Q, Zheng W, Liu C, Huang L, Zuo X, Xiao W, Han X, Ye H, Wang W, Zhu Y, Yang L
Frontiers in physiology 2022;13:844148

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Polysaccharides From the Aerial Parts of Tetrastigma Hemsleyanum Diels et Gilg Induce Bidirectional Immunity and Ameliorate LPS-Induced Acute Respiratory Distress Syndrome in Mice.

Lu J, Zhu B, Zhou F, Ding X, Qian C, Ding Z, Ye X
Frontiers in pharmacology 2022;13:838873

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Effect of Xiongmatang Extract on Behavioral and TRPV1-CGRP/CGRP-R Pathway in Rats With Migraine.

Liu D, Chang L, Wang J, Zhu Q, Jiang N, Azhar M, Ahmed A, Zeng G
Frontiers in pharmacology 2022;13:835187

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Dihydromyricetin Alleviates Pulmonary Fibrosis by Regulating Abnormal Fibroblasts Through the STAT3/p-STAT3/GLUT1 Signaling Pathway.

Li Z, Geng J, Xie B, He J, Wang J, Peng L, Hu Y, Dai H, Wang C
Frontiers in pharmacology 2022;13:834604

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Antigen Presentation Machinery Signature-Derived CALR Mediates Migration, Polarization of Macrophages in Glioma and Predicts Immunotherapy Response.

Chen R, Zhang H, Wu W, Li S, Wang Z, Dai Z, Liu Z, Zhang J, Luo P, Xia Z, Cheng Q
Frontiers in immunology 2022;13:833792

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Lactobacillus plantarum RS-09 Induces M1-Type Macrophage Immunity Against Salmonella Typhimurium Challenge via the TLR2/NF-κB Signalling Pathway.

Zhao C, Chen H, Liang H, Zhao X, Tang W, Wei M, Li Y, Zhang J, Yu X, Chen G, Zhu H, Jiang L, Zhang X
Frontiers in pharmacology 2022;13:832245

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Metformin Promotes Differentiation and Attenuates H(2)O(2)-Induced Oxidative Damage of Osteoblasts via the PI3K/AKT/Nrf2/HO-1 Pathway.

Yang K, Cao F, Qiu S, Jiang W, Tao L, Zhu Y
Frontiers in pharmacology 2022;13:829830

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Asiatic Acid Attenuates Osteoporotic Bone Loss in Ovariectomized Mice Through Inhibiting NF-kappaB/MAPK/ Protein Kinase B Signaling Pathway.

Dong M, Zeng J, Yang C, Qiu Y, Wang X
Frontiers in pharmacology 2022;13:829741

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ALG-bFGF Hydrogel Inhibiting Autophagy Contributes to Protection of Blood-Spinal Cord Barrier Integrity via PI3K/Akt/FOXO1/KLF4 Pathway After SCI.

Zhang R, Xie L, Wu F, Xu J, Lu L, Cao L, Li L, Meng W, Zhang H, Shao C, Li X, Chen D
Frontiers in pharmacology 2022;13:828896

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Trilobatin, a Natural Food Additive, Exerts Anti-Type 2 Diabetes Effect Mediated by Nrf2/ARE and IRS-1/GLUT2 Signaling Pathways.

Shi YL, Zhang YP, Luo H, Xu F, Gao JM, Shi JS, Gong QH
Frontiers in pharmacology 2022;13:828473

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Recovery Infectious Enterovirus 71 by Bac-to-Bac Expression System in vitro and in vivo.

Lu B, Tang Q, Wang Q, Liu X, Peng H, Zhu B, Xie L, Li Z, Wang H, Zheng Z, Wang L, Li B
Frontiers in microbiology 2022;13:825111

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An RRx-001 Analogue With Potent Anti-NLRP3 Inflammasome Activity but Without High-Energy Nitro Functional Groups.

Lin H, Yang M, Li C, Lin B, Deng X, He H, Zhou R
Frontiers in pharmacology 2022;13:822833

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Cold Exposure Induces Intestinal Barrier Damage and Endoplasmic Reticulum Stress in the Colon via the SIRT1/Nrf2 Signaling Pathway.

Guo J, Hu H, Chen Z, Xu J, Nie J, Lu J, Ma L, Ji H, Yuan J, Xu B
Frontiers in physiology 2022;13:822348

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Characterization of a Novel Monoclonal Antibody for Serine-129 Phosphorylated α-Synuclein: A Potential Application for Clinical and Basic Research.

Liu W, Zhang Q, Xing H, Gao G, Liu J, Huang Y, Yang H
Frontiers in neurology 2022;13:821792

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Gut microbiota-mediated metabolic restructuring aggravates emotional deficits after anesthesia/surgery in rats with preoperative stress.

Lei L, Ji M, Yang J, Chen S, Gu H, Yang JJ
Frontiers in immunology 2022;13:819289

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Propofol Augments Paclitaxel-Induced Cervical Cancer Cell Ferroptosis In Vitro.

Zhao MY, Liu P, Sun C, Pei LJ, Huang YG
Frontiers in pharmacology 2022;13:816432

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Metabolomics Analysis of the Prefrontal Cortex in a Rat Chronic Unpredictable Mild Stress Model of Depression.

Duan L, Fan R, Li T, Yang Z, Hu E, Yu Z, Tian J, Luo W, Zhang C
Frontiers in psychiatry 2022;13:815211

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OPN5 Regulating Mechanism of Follicle Development Through the TSH-DIO2/DIO3 Pathway in Mountain Ducks Under Different Photoperiods.

Liufu S, Pan J, Sun J, Shen X, Jiang D, Ouyang H, Xu D, Tian Y, Huang Y
Frontiers in physiology 2022;13:813881

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The Role of RNA-Binding Protein HuR in Lung Cancer by RNA Sequencing Analysis.

Ye X, Fu Q, Xiao H
Frontiers in genetics 2022;13:813268

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Salidroside Ameliorates Depression by Suppressing NLRP3-Mediated Pyroptosis via P2X7/NF-κB/NLRP3 Signaling Pathway.

Chai Y, Cai Y, Fu Y, Wang Y, Zhang Y, Zhang X, Zhu L, Miao M, Yan T
Frontiers in pharmacology 2022;13:812362

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Uncovering the Pharmacological Mechanisms of Gexia-Zhuyu Formula (GXZY) in Treating Liver Cirrhosis by an Integrative Pharmacology Strategy.

Cao X, Liang Y, Liu R, Zao X, Zhang J, Chen G, Liu R, Chen H, He Y, Zhang J, Ye Y
Frontiers in pharmacology 2022;13:793888

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RNA 2'-O-Methyltransferase Fibrillarin Facilitates Virus Entry Into Macrophages Through Inhibiting Type I Interferon Response.

Li P, Liu Y, Song R, Zhao L, Yang J, Lu F, Cao X
Frontiers in immunology 2022;13:793582

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Molecular Mechanisms Underlying the Inhibition of Proliferation and Differentiation by Florfenicol in P19 Stem Cells: Transcriptome Analysis.

Hu D, Zhang B, Suo Y, Li Z, Wan Z, Zhao W, Chen L, Yin Z, Ning H, Ge Y, Li W
Frontiers in pharmacology 2022;13:779664

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Cinnamaldehyde Suppressed EGF-Induced EMT Process and Inhibits Ovarian Cancer Progression Through PI3K/AKT Pathway.

Wang Y, Li Y, Wang L, Chen B, Zhu M, Ma C, Mu C, Tao A, Li S, Luo L, Ma P, Ji S, Lan T
Frontiers in pharmacology 2022;13:779608

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The Antitumor Effect and Mechanism of Total Flavonoids From Coreopsis Tinctoria Nutt (Snow Chrysanthemum) on Lung Cancer Using Network Pharmacology and Molecular Docking.

Wufuer Y, Yang X, Guo L, Aximujiang K, Zhong L, Yunusi K, Wu G
Frontiers in pharmacology 2022;13:761785

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Inflammatory-Dependent Bidirectional Effect of Bile Acids on NLRP3 Inflammasome and Its Role in Ameliorating CPT-11-Induced Colitis.

Liao C, Wang D, Qin S, Zhang Y, Chen J, Xu R, Xu F, Zhang P
Frontiers in pharmacology 2022;13:677738

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Astragalus propinquus schischkin and Salvia miltiorrhiza bunge promote angiogenesis to treat myocardial ischemia via Ang-1/Tie-2/FAK pathway.

Zhang MX, Huang XY, Song Y, Xu WL, Li YL, Li C
Frontiers in pharmacology 2022;13:1103557

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Deleterious variants in TAF7L cause human oligoasthenoteratozoospermia and its impairing histone to protamine exchange inducing reduced in vitro fertilization.

Bai H, Sha Y, Tan Y, Li P, Zhang Y, Xu J, Xu S, Ji Z, Wang X, Chen W, Zhang J, Yao C, Li Z, Zhi E
Frontiers in endocrinology 2022;13:1099270

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Wogonin increases gemcitabine sensitivity in pancreatic cancer by inhibiting Akt pathway.

Zhang T, Liu M, Liu Q, Xiao GG
Frontiers in pharmacology 2022;13:1068855

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Neuregulin-1β increases glucose uptake and promotes GLUT4 translocation in palmitate-treated C2C12 myotubes by activating PI3K/AKT signaling pathway.

Yu M, Wu S, Gong C, Chen L
Frontiers in pharmacology 2022;13:1066279

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Calycosin induces autophagy and apoptosis via Sestrin2/AMPK/mTOR in human papillary thyroid cancer cells.

Qu N, Qu J, Huang N, Zhang K, Ye T, Shi J, Chen B, Kan C, Zhang J, Han F, Hou N, Sun X, Pan R
Frontiers in pharmacology 2022;13:1056687

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Integrated network pharmacology and serum metabolomics approach deciphers the anti-colon cancer mechanisms of Huangqi Guizhi Wuwu Decoction.

Pan B, Xia Y, Fang S, Ai J, Wang K, Zhang J, Du C, Chen Y, Liu L, Yan S
Frontiers in pharmacology 2022;13:1043252

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Sleeve gastrectomy improves lipid dysmetabolism by downregulating the USP20-HSPA2 axis in diet-induced obese mice.

Zhang W, Shi B, Li S, Liu Z, Li S, Dong S, Cheng Y, Zhu J, Zhang G, Zhong M
Frontiers in endocrinology 2022;13:1041027

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Pathophysiological conditions induced by SARS-CoV-2 infection reduce ACE2 expression in the lung.

Miura Y, Ohkubo H, Nakano A, Bourke JE, Kanazawa S
Frontiers in immunology 2022;13:1028613

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Protein-protein interactions between RUNX3 and ZEB1 in chronic lung injury induced by methamphetamine abuse.

Bao N, Cheng L, Wang Y, Peng Z, Wang Z, Chen S
Frontiers in pharmacology 2022;13:1025922

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Enterovirus 71 non-structural protein 3A hijacks vacuolar protein sorting 25 to boost exosome biogenesis to facilitate viral replication.

Ruan Z, Liang Y, Chen Z, Yin J, Li C, Pan P, Zhang Q, Wu J, Luo Z
Frontiers in microbiology 2022;13:1024899

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Forsythiaside B ameliorates coagulopathies in a rat model of sepsis through inhibition of the formation of PAD4-dependent neutrophil extracellular traps.

He W, Xi Q, Cui H, Zhang P, Huang R, Wang T, Wang D
Frontiers in pharmacology 2022;13:1022985

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Improvement of gut-vascular barrier by terlipressin reduces bacterial translocation and remote organ injuries in gut-derived sepsis.

Chang Z, Zhang Y, Lin M, Wen S, Lai H, Zhan Y, Zhu X, Huang Z, Zhang X, Liu Z
Frontiers in pharmacology 2022;13:1019109

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Sleeve gastrectomy attenuated diabetes-related cognitive decline in diabetic rats.

Ding H, Liu C, Zhang S, Li B, Xu Q, Shi B, Li S, Dong S, Ma X, Zhang Y, Zhong M, Zhang G
Frontiers in endocrinology 2022;13:1015819

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Exploitation of tumor antigens and construction of immune subtype classifier for mRNA vaccine development in bladder cancer.

Zhang X, Zhang Y, Zhao L, Wang J, Li J, Wang X, Zhang M, Hu X
Frontiers in immunology 2022;13:1014638

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Clinical identification of expressed proteins in adrenal medullary hyperplasia detected with hypertension.

Ma H, Wang K, Lai B, Zhang X, Lv Y, Li R
Frontiers in endocrinology 2022;13:1014366

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Dual immunological and proliferative regulation of immune checkpoint FGL1 in lung adenocarcinoma: The pivotal role of the YY1-FGL1-MYH9 axis.

Tang XY, Xiong YL, Zhao YB, Yang J, Shi AP, Zheng KF, Liu YJ, Shu C, Jiang T, Ma N, Zhao JB
Frontiers in immunology 2022;13:1014053

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X-box binding protein 1: A new metabolic mediator and drug target of metformin?

Lou K, Sun P, Zhang C, Jiang Q, Pang S
Frontiers in pharmacology 2022;13:1013218

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Sunitinib induced hepatotoxicity in L02 cells via ROS-MAPKs signaling pathway.

Tang TL, Yang Y, Guo L, Xia S, Zhang B, Yan M
Frontiers in pharmacology 2022;13:1002142

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COA3 overexpression promotes non-small cell lung cancer metastasis by reprogramming glucose metabolism.

Lin H, Gao Y, Sun K, Zhang Q, Li Y, Chen M, Jin F
American journal of cancer research 2022;12(8):3662-3678

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M2 microglia-derived extracellular vesicles promote white matter repair and functional recovery via miR-23a-5p after cerebral ischemia in mice.

Li Y, Liu Z, Song Y, Pan JJ, Jiang Y, Shi X, Liu C, Ma Y, Luo L, Mamtilahun M, Shi Z, Khan H, Xie Q, Wang Y, Tang Y, Zhang Z, Yang GY
Theranostics 2022;12(7):3553-3573

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miR-1297 inhibits osteosarcoma cell proliferation and growth by targeting CCND2.

Jiang P, Mao L, Lei X, Luo C, Zhang Y, Zhong X, Yin Z, Xu X, Li D, Zheng Q
American journal of cancer research 2022;12(7):3464-3478

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Hepatic RACK1 deficiency protects against fulminant hepatitis through myeloid-derived suppressor cells.

Liu G, Wang Q, Deng L, Huang X, Yang G, Cheng Q, Guo T, Guo L, Niu C, Yang X, Dong J, Zhang J
Theranostics 2022;12(5):2248-2265

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Exosome-mediated delivery of RBP-J decoy oligodeoxynucleotides ameliorates hepatic fibrosis in mice.

He F, Li WN, Li XX, Yue KY, Duan JL, Ruan B, Liu JJ, Song P, Yue ZS, Tao KS, Wang L
Theranostics 2022;12(4):1816-1828

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Mitochondrial STAT3 exacerbates LPS-induced sepsis by driving CPT1a-mediated fatty acid oxidation.

Li R, Li X, Zhao J, Meng F, Yao C, Bao E, Sun N, Chen X, Cheng W, Hua H, Li X, Wang B, Wang H, Pan X, You H, Yang J, Ikezoe T
Theranostics 2022;12(2):976-998

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Methionine deprivation inhibits glioma growth through downregulation of CTSL.

Qian F, Xu H, Zhang Y, Li L, Yu R
American journal of cancer research 2022;12(11):5004-5018

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Integrative proteomics and m6A microarray analyses of the signatures induced by METTL3 reveals prognostically significant in gastric cancer by affecting cellular metabolism.

Peng G, Chen S, Zheng N, Tang Y, Su X, Wang J, Dong R, Wu D, Hu M, Zhao Y, Liu M, Wu H
Frontiers in oncology 2022;12:996329

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Identification of pyroptosis-related lncRNA signature and AC005253.1 as a pyroptosis-related oncogene in prostate cancer.

Yu J, Tang R, Li J
Frontiers in oncology 2022;12:991165

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FTO promotes liver inflammation by suppressing m6A mRNA methylation of IL-17RA.

Gan X, Dai Z, Ge C, Yin H, Wang Y, Tan J, Sun S, Zhou W, Yuan S, Yang F
Frontiers in oncology 2022;12:989353

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Construction and validation of a prognostic model with RNA binding protein-related mRNAs for the HBV-related hepatocellular carcinoma patients.

Xu S, Liu H, Tian R, Xie J, Chen S, Luo J, Zhu H, Wang Y, Li Z
Frontiers in oncology 2022;12:970613

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Effects of glycolysis and polyamine predation on intestinal epithelial barrier in colorectal cancer.

Wang Y, He H, Chen J, Song Z, Pan X, Lan T, Wang G
Frontiers in oncology 2022;12:961257

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Pan-cancer analysis reveals DDX21 as a potential biomarker for the prognosis of multiple tumor types.

Hu A, Wang Y, Tian J, Chen Z, Chen R, Han X, Chen Y, Liu T, Chen Q
Frontiers in oncology 2022;12:947054

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Silenced LINC01134 Enhances Oxaliplatin Sensitivity by Facilitating Ferroptosis Through GPX4 in Hepatocarcinoma.

Kang X, Huo Y, Jia S, He F, Li H, Zhou Q, Chang N, Liu D, Li R, Hu Y, Zhang P, Xu A
Frontiers in oncology 2022;12:939605

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CAPRIN2 upregulation by LINC00941 promotes nasopharyngeal carcinoma ferroptosis resistance and metastatic colonization through HMGCR.

Qiu L, Zhou R, Zhou L, Yang S, Wu J
Frontiers in oncology 2022;12:931749

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Loss of exosomal micro-RNA-200b-3p from hypoxia cancer-associated fibroblasts reduces sensitivity to 5-flourouracil in colorectal cancer through targeting high-mobility group box 3.

Yuan H, Chen B, Chai R, Gong W, Wan Z, Zheng B, Hu X, Guo Y, Gao S, Dai Q, Yu P, Tu S
Frontiers in oncology 2022;12:920131

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ESR1 Regulates the Obesity- and Metabolism-Differential Gene MMAA to Inhibit the Occurrence and Development of Hepatocellular Carcinoma.

Zhang Y, Cheng J, Zhong C, Xia Q, Li Y, Chen P, Fan X, Mao Q, Lin H, Hong D
Frontiers in oncology 2022;12:899969

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High-Metastatic Melanoma Cells Promote the Metastatic Capability of Low-Metastatic Melanoma Cells via Exosomal Transfer of miR-411-5p.

Chen H, Zeng B, Li X, Zhao Q, Liu D, Chen Y, Zhang Y, Wang J, Xing HR
Frontiers in oncology 2022;12:895164

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ITGB5 promotes innate radiation resistance in pancreatic adenocarcinoma by promoting DNA damage repair and the MEK/ERK signaling pathway.

Wen X, Chen S, Chen X, Qiu H, Wang W, Zhang N, Liu W, Wang T, Ding X, Zhang L
Frontiers in oncology 2022;12:887068

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TFAP2C-Mediated lncRNA PCAT1 Inhibits Ferroptosis in Docetaxel-Resistant Prostate Cancer Through c-Myc/miR-25-3p/SLC7A11 Signaling.

Jiang X, Guo S, Xu M, Ma B, Liu R, Xu Y, Zhang Y
Frontiers in oncology 2022;12:862015

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Mitochondrion-Localized SND1 Promotes Mitophagy and Liver Cancer Progression Through PGAM5.

Liang S, Zhu C, Suo C, Wei H, Yu Y, Gu X, Chen L, Yuan M, Shen S, Li S, Sun L, Gao P
Frontiers in oncology 2022;12:857968

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Up-Regulation of TRIM32 Associated With the Poor Prognosis of Acute Myeloid Leukemia by Integrated Bioinformatics Analysis With External Validation.

Xu X, Qi J, Yang J, Pan T, Han H, Yang M, Han Y
Frontiers in oncology 2022;12:848395

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FGF19 Is Coamplified With CCND1 to Promote Proliferation in Lung Squamous Cell Carcinoma and Their Combined Inhibition Shows Improved Efficacy.

Zhang Y, Wu T, Li F, Cheng Y, Han Q, Lu X, Lu S, Xia W
Frontiers in oncology 2022;12:846744

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Propofol Inhibits Proliferation and Augments the Anti-Tumor Effect of Doxorubicin and Paclitaxel Partly Through Promoting Ferroptosis in Triple-Negative Breast Cancer Cells.

Sun C, Liu P, Pei L, Zhao M, Huang Y
Frontiers in oncology 2022;12:837974

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Knockdown of hnRNPA1 Promotes NSCLC Metastasis and EMT by Regulating Alternative Splicing of LAS1L exon 9.

Han P, Cao P, Yue J, Kong K, Hu S, Deng Y, Li L, Li F, Zhao B
Frontiers in oncology 2022;12:837248

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Olaparib Induces RPL5/RPL11-Dependent p53 Activation via Nucleolar Stress.

Han T, Tong J, Wang M, Gan Y, Gao B, Chen J, Liu Y, Hao Q, Zhou X
Frontiers in oncology 2022;12:821366

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Inhibition of NEK7 Suppressed Hepatocellular Carcinoma Progression by Mediating Cancer Cell Pyroptosis.

Yan Z, Da Q, Li Z, Lin Q, Yi J, Su Y, Yu G, Ren Q, Liu X, Lin Z, Qu J, Yin W, Liu J
Frontiers in oncology 2022;12:812655

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Thymidine Kinase 1 Drives Skin Cutaneous Melanoma Malignant Progression and Metabolic Reprogramming.

Zuo S, Wang H, Li L, Pan H, Lu L
Frontiers in oncology 2022;12:802807

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Syntenin Regulated by miR-216b Promotes Cancer Progression in Pancreatic Cancer.

Zu F, Chen H, Liu Q, Zang H, Li Z, Tan X
Frontiers in oncology 2022;12:790788

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Overexpression of CDCA8 Predicts Poor Prognosis and Promotes Tumor Cell Growth in Prostate Cancer.

Wan S, He Y, Zhang B, Yang Z, Du FM, Zhang CP, Fu YQ, Mi J
Frontiers in oncology 2022;12:784183

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Transient Receptor Potential Cation Channel Subfamily V Member 1 Expression Promotes Chemoresistance in Non-Small-Cell Lung Cancer.

Li L, Chen C, Xiang Q, Fan S, Xiao T, Chen Y, Zheng D
Frontiers in oncology 2022;12:773654

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Anti-Tumor Role of CAMK2B in Remodeling the Stromal Microenvironment and Inhibiting Proliferation in Papillary Renal Cell Carcinoma.

Jia Q, Liao X, Zhang Y, Xu B, Song Y, Bian G, Fu X
Frontiers in oncology 2022;12:740051

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Dual-fluorescent reporter for live-cell imaging of the ER during DENV infection.

Corliss L, Holliday M, Lennemann NJ
Frontiers in cellular and infection microbiology 2022;12:1042735

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Inhibition of RNF182 mediated by Bap promotes non-small cell lung cancer progression.

Liu Y, Ouyang L, Mao C, Chen Y, Liu N, Chen L, Shi Y, Xiao D, Liu S, Tao Y
Frontiers in oncology 2022;12:1009508

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Polysaccharides from Vaccaria segetalis seeds reduce urinary tract infections by inhibiting the adhesion and invasion abilities of uropathogenic Escherichia coli.

Yao R, Mao X, Xu Y, Qiu X, Zhou L, Wang Y, Pang B, Chen M, Cao S, Bao L, Bao Y, Guo S, Hu L, Zhang H, Cui X
Frontiers in cellular and infection microbiology 2022;12:1004751

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Retrospective analysis of the efficacy of adjuvant cytokine-induced killer cell immunotherapy combined with chemotherapy in colorectal cancer patients after surgery.

Li X, Zhou H, Huang W, Wang X, Meng M, Hou Z, Liao L, Tang W, Xie Y, Wang R, Yu H, Wang L, Zhu H, Wang W, Tan J, Li R
Clinical & translational immunology 2022;11(1):e1368

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CAV1 alleviated CaOx stones formation via suppressing autophagy-dependent ferroptosis.

Yang Y, Hong S, Lu Y, Wang Q, Wang S, Xun Y
PeerJ 2022;10:e14033

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Involvement of PI3K/Akt signaling pathway in promoting osteogenesis on titanium implant surfaces modified with novel non-thermal atmospheric plasma.

Zheng Z, He Y, Long L, Gan S, Chen S, Zhang M, Xu J, Fu R, Liao Y, Zhu Z, Wang H, Chen W
Frontiers in bioengineering and biotechnology 2022;10:975840

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Adhesive, injectable, and ROS-responsive hybrid polyvinyl alcohol (PVA) hydrogel co-delivers metformin and fibroblast growth factor 21 (FGF21) for enhanced diabetic wound repair.

Zhu H, Xu J, Zhao M, Luo H, Lin M, Luo Y, Li Y, He H, Wu J
Frontiers in bioengineering and biotechnology 2022;10:968078

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Expression profiles of exosomal tRNA-derived fragments and their biological functions in lipomas.

Zhou Y, Tao D, Shao Z, Wang X, Xu J, Li Y, Li K
Frontiers in cell and developmental biology 2022;10:942133

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Manganese-Based Prussian Blue Nanocatalysts Suppress Non-Small Cell Lung Cancer Growth and Metastasis via Photothermal and Chemodynamic Therapy.

Fang D, Liu Z, Jin H, Huang X, Shi Y, Ben S
Frontiers in bioengineering and biotechnology 2022;10:939158

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Extracellular vimentin is expressed at the rear of activated macrophage-like cells: Potential role in enhancement of migration and phagocytosis.

Thalla DG, Rajwar AC, Laurent AM, Becher JE, Kainka L, Lautenschläger F
Frontiers in cell and developmental biology 2022;10:891281

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The Apoptotic Resistance of BRCA1-Deficient Ovarian Cancer Cells is Mediated by cAMP.

Yue W, Ma J, Xiao Y, Wang P, Gu X, Xie B, Li M
Frontiers in cell and developmental biology 2022;10:889656

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The Maternal Microbiome Programs the m(6)A Epitranscriptome of the Mouse Fetal Brain and Intestine.

Xiao Z, Liu S, Li Z, Cui J, Wang H, Wang Z, Ren Q, Xia L, Wang Z, Li Y
Frontiers in cell and developmental biology 2022;10:882994

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Umbilical Cord Mesenchymal Stem Cells Ameliorate Kidney Injury in MRL/Ipr Mice Through the TGF-β1 Pathway.

Huang C, Meng M, Li S, Liu S, Li L, Su Y, Gao H, He S, Zhao Y, Zhang M, Hou Z, Wang W, Wang X
Frontiers in cell and developmental biology 2022;10:876054

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Reciprocal Regulation of Mitofusin 2-Mediated Mitophagy and Mitochondrial Fusion by Different PINK1 Phosphorylation Events.

Li J, Dang X, Franco A, Dorn GW 2nd
Frontiers in cell and developmental biology 2022;10:868465

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AZD5153, a Bivalent BRD4 Inhibitor, Suppresses Hepatocarcinogenesis by Altering BRD4 Chromosomal Landscape and Modulating the Transcriptome of HCC Cells.

Lin CH, Kuo JC, Li D, Koenig AB, Pan A, Yan P, Bai XF, Lee RJ, Ghoshal K
Frontiers in cell and developmental biology 2022;10:853652

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miR-381-3p Cooperated With Hes1 to Regulate the Proliferation and Differentiation of Retinal Progenitor Cells.

Wang J, Sun N, Ju Y, Ni N, Tang Z, Zhang D, Dai X, Chen M, Wang Y, Gu P, Ji J
Frontiers in cell and developmental biology 2022;10:853215

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Elucidating the Potential Mechanisms Underlying Distraction Spinal Cord Injury-Associated Neuroinflammation and Apoptosis.

Han B, Liang W, Hai Y, Liu Y, Chen Y, Ding H, Yang J, Yin P
Frontiers in cell and developmental biology 2022;10:839313

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Adenosine Kinase Inhibition Prevents Severe Acute Pancreatitis via Suppressing Inflammation and Acinar Cell Necroptosis.

Sun S, Han Y, Zhang C, Liu H, Wang B, Cao S, Yuan Q, Wei S, Chen Y
Frontiers in cell and developmental biology 2022;10:827714

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Inhibition of the NLRP3 Inflammasome Activation by Manoalide Ameliorates Experimental Autoimmune Encephalomyelitis Pathogenesis.

Li C, Lin H, He H, Ma M, Jiang W, Zhou R
Frontiers in cell and developmental biology 2022;10:822236

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PLK1 Mitigates Intervertebral Disc Degeneration by Delaying Senescence of Nucleus Pulposus Cells.

Zhang Z, Huang Y, Xu N, Wang J, Yao T, Xu Y, Qiao D, Gao J, Shen S, Ma J
Frontiers in cell and developmental biology 2022;10:819262

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Quercetin Administration Following Hypoxia-Induced Neonatal Brain Damage Attenuates Later-Life Seizure Susceptibility and Anxiety-Related Behavior: Modulating Inflammatory Response.

Wu Y, Wei H, Li P, Zhao H, Li R, Yang F
Frontiers in pediatrics 2022;10:791815

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Platelet-rich plasma attenuates the severity of joint capsule fibrosis following post-traumatic joint contracture in rats.

Zhang Y, Wang Z, Zong C, Gu X, Fan S, Xu L, Cai B, Lu S
Frontiers in bioengineering and biotechnology 2022;10:1078527

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Construction and osteogenic effects of 3D-printed porous titanium alloy loaded with VEGF/BMP-2 shell-core microspheres in a sustained-release system.

Liu Z, Xu Z, Wang X, Zhang Y, Wu Y, Jiang D, Jia R
Frontiers in bioengineering and biotechnology 2022;10:1028278

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BCAT1 promotes lung adenocarcinoma progression through enhanced mitochondrial function and NF-κB pathway activation.

Yu M, Zhao Q, Li J, Xu F, Zhang Z, Liu Y, Dai L, Zhang B, Zhang J, Zhang J
Journal of Zhejiang University. Science. B 2022 Sept 15;23(9):760-769

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The E3 Ligase TRIM4 Facilitates SET Ubiquitin-Mediated Degradation to Enhance ER-α Action in Breast Cancer.

Han D, Wang L, Long L, Su P, Luo D, Zhang H, Li Z, Chen B, Zhao W, Zhang N, Wang X, Liang Y, Li Y, Hu G, Yang Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Sep;9(25):e2201701

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Icariside II suppresses the tumorigenesis and development of ovarian cancer by regulating miR-144-3p/IGF2R axis.

Yuan D, Guo T, Qian H, Ge H, Zhao Y, Huang A, Wang X, Cao X, Zhu D, He C, Yu H
Drug development research 2022 Sep;83(6):1383-1393

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Quercetin ameliorates salivary gland apoptosis and inflammation in primary Sjögren's syndrome through regulation of the leptin/OB-R signaling.

Chang L, Kong A, Guo Y, Zhang J, Sun Y, Chen P, Wang X
Drug development research 2022 Sep;83(6):1351-1361

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Carotenoid transporter CD36 expression depends on hypoxia-inducible factor-1α in mouse soleus muscles.

Kitakaze T, Sugihira T, Kameyama H, Maruchi A, Kobayashi Y, Harada N, Yamaji R
Journal of clinical biochemistry and nutrition 2022 Sep;71(2):112-121

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HSPA5 repressed ferroptosis to promote colorectal cancer development by maintaining GPX4 stability.

Wang R, Hua L, Ma P, Song Y, Min J, Guo Y, Yang C, Li J, Su H
Neoplasma 2022 Sep;69(5):1054-1069

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Insulin Deficiency Increases Sirt2 Level in Streptozotocin-Treated Alzheimer's Disease-Like Mouse Model: Increased Sirt2 Induces Tau Phosphorylation Through ERK Activation.

Zhou C, Jung CG, Kim MJ, Watanabe A, Abdelhamid M, Taslima F, Michikawa M
Molecular neurobiology 2022 Sep;59(9):5408-5425

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Nav1.8 in keratinocytes contributes to ROS-mediated inflammation in inflammatory skin diseases.

Zhang Y, Li Y, Zhou L, Yuan X, Wang Y, Deng Q, Deng Z, Xu S, Wang Q, Xie H, Li J
Redox biology 2022 Sep;55:102427

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A possible mechanism to the antidepressant-like effects of 20 (S)-protopanaxadiol based on its target protein 14-3-3 ζ.

Chen L, Li R, Chen F, Zhang H, Zhu Z, Xu S, Cheng Y, Zhao Y
Journal of ginseng research 2022 Sep;46(5):666-674

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KRAS-G12D mutation drives immune suppression and the primary resistance of anti-PD-1/PD-L1 immunotherapy in non-small cell lung cancer.

Liu C, Zheng S, Wang Z, Wang S, Wang X, Yang L, Xu H, Cao Z, Feng X, Xue Q, Wang Y, Sun N, He J
Cancer communications (London, England) 2022 Sep;42(9):828-847

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Serum-derived exosomes from SD rats induce inflammation in macrophages through the mTOR pathway.

Wang Y, Liu YP, Sun ZB, Deng WH, Yuan XY, Lei YD, Cai Y, Huang L, Zhang ZH
Journal of applied toxicology : JAT 2022 Sep;42(9):1524-1532

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FumDSB can alleviate the inflammatory response induced by fumonisin B(1) in growing pigs.

Liu Q, Huang L, Cui Z, Qiao B, Li F, Wang C
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 2022 Sep;39(9):1619-1633

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Exosomal miR-7002-5p derived from highglucose-induced macrophages suppresses autophagy in tubular epithelial cells by targeting Atg9b.

Zhao J, Chen J, Zhu W, Qi XM, Wu YG
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Sep;36(9):e22501

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Androgen receptor splicing variant 7 (ARv7) promotes DNA damage response in prostate cancer cells.

Luo H, Liu Y, Li Y, Zhang C, Yu B, Shao C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Sep;36(9):e22495

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Trehalose improves palmitic acid-induced apoptosis of osteoblasts by regulating SIRT3-medicated autophagy via the AMPK/mTOR/ULK1 pathway.

Cao L, Zhou S, Qiu X, Qiu S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Sep;36(9):e22491

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A novel role of TCAIM: suppressing renal carcinoma growth and enhancing its sensitivity to sunitinib.

Ye Z, Ren C, Wang Q, Wang Y
The FEBS journal 2022 Sep;289(17):5259-5278

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Rare variants in GABRG2 associated with sleep-related hypermotor epilepsy.

Jiang YL, Song CG, Zhou HM, Feng B, Zhao JJ, Liu Y, Man YL, Han J, Liu SB, Jiang W
Journal of neurology 2022 Sep;269(9):4939-4954

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Identification of ferroptosis-related genes for the prediction of prognosis and chemotherapy benefit of gastric cancer.

Zheng JJ, Wang JP
European review for medical and pharmacological sciences 2022 Sep;26(18):6754-6763

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Epigallocatechin-3-gallate attenuates myocardial fibrosis in diabetic rats by activating autophagy.

Jia Q, Yang R, Mehmood S, Li Y
Experimental biology and medicine (Maywood, N.J.) 2022 Sep;247(17):1591-1600

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Integrated analysis of ALK higher expression in human cancer and downregulation in LUAD using RNA molecular scissors.

Saifullah, Tsukahara T
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2022 Sep;24(9):1785-1799

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Salvianolic Acid B Alleviates Myocardial Ischemia Injury by Suppressing NLRP3 Inflammasome Activation via SIRT1-AMPK-PGC-1α Signaling Pathway.

Li Q, Zuo Z, Pan Y, Zhang Q, Xu L, Jiang B
Cardiovascular toxicology 2022 Sep;22(9):842-857

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Inhibition of 8-oxoguanine DNA glycosylase (OGG1) expression suppresses polycystic ovarian syndrome via the NF-κB signaling pathway.

Xia J, Wu S, Wu G, Yang J
Reproductive biology 2022 Sep;22(3):100679

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DI-3-n-butylphthalide mitigates stress-induced cognitive deficits in mice through inhibition of NLRP3-Mediated neuroinflammation.

Chen X, He JL, Liu XT, Zhao N, Geng F, Zhu MM, Liu GP, Ren QG
Neurobiology of stress 2022 Sep;20:100486

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High-circulating gut microbiota-dependent metabolite trimethylamine N-oxide is associated with poor prognosis in pulmonary arterial hypertension.

Yang Y, Zeng Q, Gao J, Yang B, Zhou J, Li K, Li L, Wang A, Li X, Liu Z, Luo Q, Zhao Z, Liu B, Xue J, Jiang X, Konerman MC, Zheng L, Xiong C
European heart journal open 2022 Sep;2(5):oeac021

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Protective effects of fraxin on cerebral ischemia-reperfusion injury by mediating neuroinflammation and oxidative stress through PPAR-γ/NF-κB pathway.

Yao H, Zhao J, Song X
Brain research bulletin 2022 Sep;187:49-62

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Transcranial focused ultrasound stimulation reduces vasogenic edema after middle cerebral artery occlusion in mice.

Deng LD, Qi L, Suo Q, Wu SJ, Mamtilahun M, Shi RB, Liu Z, Sun JF, Tang YH, Zhang ZJ, Yang GY, Wang JX
Neural regeneration research 2022 Sep;17(9):2058-2063

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Urolithin A alleviates blood-brain barrier disruption and attenuates neuronal apoptosis following traumatic brain injury in mice.

Gong QY, Cai L, Jing Y, Wang W, Yang DX, Chen SW, Tian HL
Neural regeneration research 2022 Sep;17(9):2007-2013

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Phospho-proteomics reveals that RSK signaling is required for proliferation of natural killer cells stimulated with IL-2 or IL-15.

MacMullan MA, Wang P, Graham NA
Cytokine 2022 Sep;157:155958

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Effect of flavonoids from Rhizoma Drynariae on osteoporosis rats and osteocytes.

Jin H, Jiang N, Xu W, Zhang Z, Yang Y, Zhang J, Xu H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113379

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Compromised glycolysis contributes to foot process fusion of podocytes in diabetic kidney disease: Role of ornithine catabolism.

Luo Q, Liang W, Zhang Z, Zhu Z, Chen Z, Hu J, Yang K, Chi Q, Ding G
Metabolism: clinical and experimental 2022 Sep;134:155245

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NF-κB-coupled IL17 mediates inflammatory signaling and intestinal inflammation in Artemia sinica.

Wang Z, Sun X, Wang W, Zheng M, Zhang D, Yin H
Fish & shellfish immunology 2022 Sep;128:38-49

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LncRNA DACH1 protects against pulmonary fibrosis by binding to SRSF1 to suppress CTNNB1 accumulation.

Sun J, Jin T, Niu Z, Guo J, Guo Y, Yang R, Wang Q, Gao H, Zhang Y, Li T, He W, Li Z, Ma W, Su W, Li L, Fan X, Shan H, Liang H
Acta pharmaceutica Sinica. B 2022 Sep;12(9):3602-3617

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The ubiquitin-26S proteasome system and autophagy relay proteome homeostasis regulation during silique development.

Yu P, Hua Z
The Plant journal : for cell and molecular biology 2022 Sep;111(5):1324-1339

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7-O-(2- (Propylamino)-2-oxoethyl) hesperetin attenuates inflammation and protects against alcoholic liver injury by NLRP12.

Niu XN, Zhang YL, Cheng M, Yin NN, Wu YY, Shi W, Yang YL, Zhu L, Huang C, Li J
International immunopharmacology 2022 Sep;110:109006

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Hirudin alleviates acute ischemic stroke by inhibiting NLRP3 inflammasome-mediated neuroinflammation: In vivo and in vitro approaches.

Li WQ, Qin ZS, Chen S, Cheng D, Yang SC, Choi YMM, Chu B, Zhou WH, Zhang ZJ
International immunopharmacology 2022 Sep;110:108967

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High expression of PTGES3 is an independent predictive poor prognostic biomarker and correlates with immune infiltrates in lung adenocarcinoma.

Gao P, Zou K, Xiao L, Zhou H, Xu X, Zeng Z, Zhang W
International immunopharmacology 2022 Sep;110:108954

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Neobavaisoflavone inhibits allergic inflammatory responses by suppressing mast cell activation.

Liang R, Yuan Y, Bai Y, Liu X, Chen J, Jiang D, Meng D, Chen G, Li B, Zhou L, Guo W
International immunopharmacology 2022 Sep;110:108953

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Luteolin ameliorates hypoxia-induced pulmonary hypertension via regulating HIF-2α-Arg-NO axis and PI3K-AKT-eNOS-NO signaling pathway.

Ji L, Su S, Xin M, Zhang Z, Nan X, Li Z, Lu D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154329

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Iristectorigenin A exerts novel protective properties against airway inflammation and mucus hypersecretion in OVA-induced asthmatic mice: Iristectorigenin A ameliorates asthma phenotype.

Wuniqiemu T, Teng F, Qin J, Lv Y, Nabijan M, Luo Q, Zhou Y, Cui J, Yi L, Tang W, Zhu X, Amangu, Wang S, Abduwaki M, Nurahmat M, Wei Y, Dong JC
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154252

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Serum exosomal coronin 1A and dynamin 2 as neural tube defect biomarkers.

Wang Y, Ma L, Jia S, Liu D, Gu H, Wei X, Ma W, Luo W, Bai Y, Wang W, Yuan Z
Journal of molecular medicine (Berlin, Germany) 2022 Sep;100(9):1307-1319

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Biomimetic cytomembrane-coated ZIF-8-loaded DMDD nanoparticle and sonodynamic co-therapy for cancer.

Zhao S, Chen M, Yu Z, Pham TTH, Mo S, He Y, Liang T, Cao W, Han C
Annals of translational medicine 2022 Sep;10(18):971

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Growth advantage of corrected hepatocytes in a juvenile model of methylmalonic acidemia following liver directed adeno-associated viral mediated nuclease-free genome editing.

Venturoni LE, Chandler RJ, Liao J, Hoffmann V, Ramesh N, Gordo S, Chau N, Venditti CP
Molecular genetics and metabolism 2022 Sep-Oct;137(1-2):1-8

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Achyranthoside D (AD) improve intervertebral disc degeneration through affect the autophagy and the activation of PI3K/Akt/mTOR pathway.

Zhang C, Li Z, Li L, Li S, Yang L, Chen L, Zhang X, Yang S, Guo Y
Journal of orthopaedic surgery (Hong Kong) 2022 Sep-Dec;30(3):10225536221135474

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Topoisomerase IIA in adult NSCs regulates SVZ neurogenesis by transcriptional activation of Usp37.

Qin S, Yuan Y, Huang X, Tan Z, Hu X, Liu H, Pu Y, Ding YQ, Su Z, He C
Nucleic acids research 2022 Sep 9;50(16):9319-9338

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Integrative network analysis of circular RNAs reveals regulatory mechanisms for hepatic specification of human iPSC-derived endoderm.

Bai F, Duan J, Yang D, Lai X, Zhu X, He X, Hu A
Stem cell research & therapy 2022 Sep 8;13(1):468

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Identification of a small-molecule RPL11 mimetic that inhibits tumor growth by targeting MDM2-p53 pathway.

Wang B, Gao J, Zhao Z, Zhong X, Cui H, Hou H, Zhang Y, Zheng J, Di J, Liu Y
Molecular medicine (Cambridge, Mass.) 2022 Sep 7;28(1):109

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Acid ceramidase targeting pyruvate kinase affected trypsinogen activation in acute pancreatitis.

Xiao J, Zeng W, Zhang P, Zhou Y, Fang Q
Molecular medicine (Cambridge, Mass.) 2022 Sep 6;28(1):106

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The histone modification reader ZCWPW1 promotes double-strand break repair by regulating cross-talk of histone modifications and chromatin accessibility at meiotic hotspots.

Yuan S, Huang T, Bao Z, Wang S, Wu X, Liu J, Liu H, Chen ZJ
Genome biology 2022 Sep 6;23(1):187

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TRIM46 aggravated high glucose-induced hyper permeability and inflammatory response in human retinal capillary endothelial cells by promoting IκBα ubiquitination.

Shen H, Gong Q, Zhang J, Wang H, Qiu Q, Zhang J, Luo D
Eye and vision (London, England) 2022 Sep 5;9(1):35

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Membrane-associated RING-CH protein (MARCH8) is a novel glycolysis repressor targeted by miR-32 in colorectal cancer.

Wang Z, Wang MM, Geng Y, Ye CY, Zang YS
Journal of translational medicine 2022 Sep 5;20(1):402

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The MBNL1/circNTRK2/PAX5 pathway regulates aerobic glycolysis in glioblastoma cells by encoding a novel protein NTRK2-243aa.

Zhao Y, Song J, Dong W, Liu X, Yang C, Wang D, Xue Y, Ruan X, Liu L, Wang P, Zhang M, Liu Y
Cell death & disease 2022 Sep 5;13(9):767

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CLDN4 promotes growth of acute myeloid leukemia cells via regulating AKT and ERK1/2 signaling.

Hao S, Yang C, Song P, Shi H, Zou Y, Chen M, Wu X, Yin Y, Yu Z, Zhu W, Li M
Biochemical and biophysical research communications 2022 Sep 3;619:137-143

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FOXD1 facilitates pancreatic cancer cell proliferation, invasion, and metastasis by regulating GLUT1-mediated aerobic glycolysis.

Cai K, Chen S, Zhu C, Li L, Yu C, He Z, Sun C
Cell death & disease 2022 Sep 3;13(9):765

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Inhibition of Mcl-1 Synergistically Enhances the Antileukemic Activity of Gilteritinib and MRX-2843 in Preclinical Models of FLT3-Mutated Acute Myeloid Leukemia.

Wu S, Edwards H, Wang D, Liu S, Qiao X, Carter J, Wang Y, Taub JW, Wang G, Ge Y
Cells 2022 Sep 3;11(17)

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SPLUNC1 regulates LPS-induced progression of nasopharyngeal carcinoma and proliferation of myeloid-derived suppressor cells.

Tang L, Peng L, Liu H, Xiao T, Gu W, Yang H, Wang H, Chen P
Medical oncology (Northwood, London, England) 2022 Sep 29;39(12):214

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Exosomal miR-22-3p from Mesenchymal Stem Cells Inhibits the Epithelial-Mesenchymal Transition (EMT) of Melanoma Cells by Regulating LGALS1.

Chen Y, Fang Y, Li L, Luo H, Cao T, Tu B
Frontiers in bioscience (Landmark edition) 2022 Sep 29;27(9):275

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Effects of growth hormone/estrogen/androgen on COVID-19-type proinflammatory responses in normal human lung epithelial BEAS-2B cells.

Zhu Z, Zhao Z, Chen X, Chu Z, He Y, Tan Y, Zhou J, Tang C
BMC molecular and cell biology 2022 Sep 29;23(1):42

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Grass Carp Prx 3 Elevates Host Antioxidant Activity and Induces Autophagy to Inhibit Grass Carp Reovirus (GCRV) Replication.

Liang X, Li Y, Chu P, Wang Q, Wang H, Liao L, Yang C, Zhu Z, Wang Y, He L
Antioxidants (Basel, Switzerland) 2022 Sep 29;11(10)

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Rabphilin 3A binds the N-peptide of SNAP-25 to promote SNARE complex assembly in exocytosis.

Li T, Cheng Q, Wang S, Ma C
eLife 2022 Sep 29;11

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Nonstructural Protein 1 of Variant PEDV Plays a Key Role in Escaping Replication Restriction by Complement C3.

Fan B, Peng Q, Song S, Shi D, Zhang X, Guo W, Li Y, Zhou J, Zhu X, Zhao Y, Guo R, He K, Fan H, Ding S, Li B
Journal of virology 2022 Sep 28;96(18):e0102422

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Single cell analysis of PANoptosome cell death complexes through an expansion microscopy method.

Wang Y, Pandian N, Han JH, Sundaram B, Lee S, Karki R, Guy CS, Kanneganti TD
Cellular and molecular life sciences : CMLS 2022 Sep 28;79(10):531

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Post-Injury Buprenorphine Administration Is Associated with Long-Term Region-Specific Glial Alterations in Rats.

Ryu J, Jeizan P, Ahmed S, Ehsan S, Jose J, Regan S, Gorse K, Kelliher C, Lafrenaye A
Pharmaceutics 2022 Sep 28;14(10)

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Impad1 and Syt11 work in an epistatic pathway that regulates EMT-mediated vesicular trafficking to drive lung cancer invasion and metastasis.

Bajaj R, Rodriguez BL, Russell WK, Warner AN, Diao L, Wang J, Raso MG, Lu W, Khan K, Solis LS, Batra H, Tang X, Fradette JF, Kundu ST, Gibbons DL
Cell reports 2022 Sep 27;40(13):111429

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Inhibiting ALK-TOPK signaling pathway promotes cell apoptosis of ALK-positive NSCLC.

Xiao J, Zhang L, Yi H, Zou L, Mo J, Xue F, Zheng J, Huang Y, Lu H, Wu H, Xue P, Zhang X, He L, Li Z, Pang S, Qiao G, Duan Q, Zhu F
Cell death & disease 2022 Sep 27;13(9):828

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Differential requirements for mitochondrial electron transport chain components in the adult murine liver.

Lesner NP, Wang X, Chen Z, Frank A, Menezes CJ, House S, Shelton SD, Lemoff A, McFadden DG, Wansapura J, DeBerardinis RJ, Mishra P
eLife 2022 Sep 26;11

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PIKE-A Modulates Mitochondrial Metabolism through Increasing SDHA Expression Mediated by STAT3/FTO Axis.

Sun M, Yan Q, Qiao Y, Zhao H, Wang Y, Shan C, Zhang S
International journal of molecular sciences 2022 Sep 25;23(19)

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Exploring Active Ingredients, Beneficial Effects, and Potential Mechanism of Allium tenuissimum L. Flower for Treating T2DM Mice Based on Network Pharmacology and Gut Microbiota.

Zhang SS, Hou YF, Liu SJ, Guo S, Ho CT, Bai NS
Nutrients 2022 Sep 25;14(19)

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7-aminocephalosporanic acid, a novel HSP90β inhibitor, attenuates HFD-induced hepatic steatosis.

Zhang W, Xue H, Zhou C, Zheng Z, Xing M, Chu H, Li P, Zhang N, Dang Y, Xu X
Biochemical and biophysical research communications 2022 Sep 24;622:184-191

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Gastrodin Ameliorates Cognitive Dysfunction in Vascular Dementia Rats by Suppressing Ferroptosis via the Regulation of the Nrf2/Keap1-GPx4 Signaling Pathway.

Li Y, Zhang E, Yang H, Chen Y, Tao L, Xu Y, Chen T, Shen X
Molecules (Basel, Switzerland) 2022 Sep 24;27(19)

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PKM2 promotes pulmonary fibrosis by stabilizing TGF-β1 receptor I and enhancing TGF-β1 signaling.

Gao S, Li X, Jiang Q, Liang Q, Zhang F, Li S, Zhang R, Luan J, Zhu J, Gu X, Xiao T, Huang H, Chen S, Ning W, Yang G, Yang C, Zhou H
Science advances 2022 Sep 23;8(38):eabo0987

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Design, Synthesis, and Biological Evaluation of Androgen Receptor Degrading and Antagonizing Bifunctional Steroidal Analogs for the Treatment of Advanced Prostate Cancer.

Wang A, Luo X, Wang Y, Meng X, Lu Z, Yang Y
Journal of medicinal chemistry 2022 Sep 22;65(18):12460-12481

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Akebia Saponin D Inhibits the Inflammatory Reaction by Inhibiting the IL-6-STAT3-DNMT3b Axis and Activating the Nrf2 Pathway.

Luo JF, Zhou H, Lio CK
Molecules (Basel, Switzerland) 2022 Sep 22;27(19)

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TOP2A deficit-induced abnormal decidualization leads to recurrent implantation failure via the NF-κB signaling pathway.

Fu H, Tan W, Chen Z, Ye Z, Duan Y, Huang J, Qi H, Liu X
Reproductive biology and endocrinology : RB&E 2022 Sep 22;20(1):142

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SHP-1/STAT3-Signaling-Axis-Regulated Coupling between BECN1 and SLC7A11 Contributes to Sorafenib-Induced Ferroptosis in Hepatocellular Carcinoma.

Huang CY, Chen LJ, Chen G, Chao TI, Wang CY
International journal of molecular sciences 2022 Sep 21;23(19)

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Correlation of the prognostic value of FNDC4 in glioblastoma with macrophage polarization.

Li H, Yan X, Ou S
Cancer cell international 2022 Sep 2;22(1):273

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A causal variant rs3769823 in 2q33.1 involved in apoptosis pathway leading to a decreased risk of non-small cell lung cancer.

Zhang X, Qin N, Fan J, Zhang C, Sun Q, Gu Y, Zhu M, Zhang E, Dai J, Jin G, Ma H, Hu Z, Shen H
Cancer biology & medicine 2022 Sep 2;19(9):1385-96

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KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer.

Yao H, Ren D, Wang Y, Wu L, Wu Y, Wang W, Li Q, Liu L
Cell death & disease 2022 Sep 2;13(9):761

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Asiatic Acid Attenuates Inflammation Induced by Salmonella via Upregulating LncRNA TVX1 in Microglia.

Zou W, Zhang J, Zhang K, Peng Z, Xin R, Wang L, Li J
International journal of molecular sciences 2022 Sep 19;23(18)

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TWIST1 induces proteasomal degradation of β-catenin during the differentiation of ovarian cancer stem-like cells.

Liu J, Shu G, Wu A, Zhang X, Zhou Z, Alvero AB, Mor G, Yin G
Scientific reports 2022 Sep 19;12(1):15650

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Isoalantolactone (IAL) Regulates Neuro-Inflammation and Neuronal Apoptosis to Curb Pathology of Parkinson's Disease.

He D, Liu Y, Li J, Wang H, Ye B, He Y, Li Z, Gao X, Fu S, Liu D
Cells 2022 Sep 19;11(18)

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PD-1 Alleviates Cisplatin-Induced Muscle Atrophy by Regulating Inflammation and Oxidative Stress.

Liu X, Xu M, Yu Y, Chen Y, Weng X, Zhu L
Antioxidants (Basel, Switzerland) 2022 Sep 18;11(9)

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CTCF DNA-binding domain undergoes dynamic and selective protein-protein interactions.

Zhou R, Tian K, Huang J, Duan W, Fu H, Feng Y, Wang H, Jiang Y, Li Y, Wang R, Hu J, Ma H, Qi Z, Ji X
iScience 2022 Sep 16;25(9):105011

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Pericyte mediates the infiltration, migration, and polarization of macrophages by CD163/MCAM axis in glioblastoma.

Zhang H, Zhang N, Wu W, Wang Z, Dai Z, Liang X, Zhang L, Peng Y, Luo P, Zhang J, Liu Z, Cheng Q, Liu Z
iScience 2022 Sep 16;25(9):104918

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Kaempferol impairs aerobic glycolysis against melanoma metastasis via inhibiting the mitochondrial binding of HK2 and VDAC1.

Zheng X, Pan Y, Yang G, Liu Y, Zou J, Zhao H, Yin G, Wu Y, Li X, Wei Z, Yu S, Zhao Y, Wang A, Chen W, Lu Y
European journal of pharmacology 2022 Sep 15;931:175226

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Alpha1B-adreneroceptor is involved in norepinephrine-induced pulmonary artery smooth muscle cell proliferation via p38 signaling.

Xiao X, Zhang Y, Tian S, Wang X, Zhang Q, Zhang L, Yu X, Ma C, Zheng X, Li Y, Zhang J, Qu L
European journal of pharmacology 2022 Sep 15;931:175159

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Aberrant human ClpP activation disturbs mitochondrial proteome homeostasis to suppress pancreatic ductal adenocarcinoma.

Wang P, Zhang T, Wang X, Xiao H, Li H, Zhou LL, Yang T, Wei B, Zhu Z, Zhou L, Yang S, Lu X, Zhang Y, Huang Y, Gan J, Yang CG
Cell chemical biology 2022 Sep 15;29(9):1396-1408.e8

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Purple sweet potato delphinidin-3-rutin represses glioma proliferation by inducing miR-20b-5p/Atg7-dependent cytostatic autophagy.

Wang M, Liu K, Bu H, Cong H, Dong G, Xu N, Li C, Zhao Y, Jiang F, Zhang Y, Yuan B, Li R, Jiang J
Molecular therapy oncolytics 2022 Sep 15;26:314-329

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African Swine Fever Virus pI215L Inhibits Type I Interferon Signaling by Targeting Interferon Regulatory Factor 9 for Autophagic Degradation.

Li L, Fu J, Li J, Guo S, Chen Q, Zhang Y, Liu Z, Tan C, Chen H, Wang X
Journal of virology 2022 Sep 14;96(17):e0094422

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CIDEA Regulates De Novo Fatty Acid Synthesis in Bovine Mammary Epithelial Cells by Targeting the AMPK/PPARγ Axis and Regulating SREBP1.

Cheng J, Xu D, Chen L, Guo W, Hu G, Liu J, Fu S
Journal of agricultural and food chemistry 2022 Sep 14;70(36):11324-11335

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Chemically modified in-vitro-transcribed mRNA encoding thrombopoietin stimulates thrombopoiesis in mice.

Zhang Y, Xi X, Yu H, Yang L, Lin J, Yang W, Liu J, Fan X, Xu Y
Molecular therapy. Nucleic acids 2022 Sep 13;29:657-671

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Deubiquitination of BES1 by UBP12/UBP13 promotes brassinosteroid signaling and plant growth.

Park SH, Jeong JS, Zhou Y, Binte Mustafa NF, Chua NH
Plant communications 2022 Sep 12;3(5):100348

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Direct conversion of human umbilical cord mesenchymal stem cells into retinal pigment epithelial cells for treatment of retinal degeneration.

Zhu X, Chen Z, Wang L, Ou Q, Feng Z, Xiao H, Shen Q, Li Y, Jin C, Xu JY, Gao F, Wang J, Zhang J, Zhang J, Xu Z, Xu GT, Lu L, Tian H
Cell death & disease 2022 Sep 12;13(9):785

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GCAF(TMEM251) regulates lysosome biogenesis by activating the mannose-6-phosphate pathway.

Zhang W, Yang X, Li Y, Yu L, Zhang B, Zhang J, Cho WJ, Venkatarangan V, Chen L, Burugula BB, Bui S, Wang Y, Duan C, Kitzman JO, Li M
Nature communications 2022 Sep 12;13(1):5351

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COPS5 Conferred the Platinum Resistance in Epithelial Ovarian Cancer.

Zhang H, Yan T, Zhong A, Guo L, Lu R
Current issues in molecular biology 2022 Sep 1;44(9):3948-3958

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MCPIP1 promotes cell proliferation, migration and angiogenesis of glioma via VEGFA-mediated ERK pathway.

Wang R, Sun S, Wang Z, Xu X, Jiang T, Liu H, Li X, Ren Z
Experimental cell research 2022 Sep 1;418(1):113267

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Flufenamic acid improves survival and neurologic outcome after successful cardiopulmonary resuscitation in mice.

Chen J, Chang Y, Zhu J, Peng Y, Li Z, Zhang K, Zhang Y, Lin C, Lin Z, Pan S, Huang K
Journal of neuroinflammation 2022 Sep 1;19(1):214

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Tumor-intrinsic PRC2 inactivation drives a context-dependent immune-desert microenvironment and is sensitized by immunogenic viruses.

Yan J, Chen Y, Patel AJ, Warda S, Lee CJ, Nixon BG, Wong EW, Miranda-Román MA, Yang N, Wang Y, Pachai MR, Sher J, Giff E, Tang F, Khurana E, Singer S, Liu Y, Galbo PM Jr, Maag JL, Koche RP, Zheng D, Antonescu CR, Deng L, Li MO, Chen Y, Chi P
The Journal of clinical investigation 2022 Sep 1;132(17)

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Metabolism-Based Molecular Subtyping Endows Effective Ketogenic Therapy in p53-Mutant Colon Cancer.

Tang M, Xu H, Huang H, Kuang H, Wang C, Li Q, Zhang X, Ge Y, Song M, Zhang X, Wang Z, Ma C, Kang J, Zhang W, Wang Y, Zhang B, Zhang X, Chen Y, Cong M, Melino G, Wang X, Zhou F, Sun Q, Shi H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Oct;9(29):e2201992

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TCQA, A Natural Caffeoylquinic Acid Derivative Attenuates H2O2-Induced Neuronal Apoptosis by Suppressing Phosphorylation of MAPKs Signaling Pathway.

Yang Y, Ding Y, Gao H, Jiang X, Zhao Q
Planta medica 2022 Oct;88(13):1132-1140

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Identification of active natural products that induce lysosomal biogenesis by lysosome-based screening and biological evaluation.

Ding X, Yang X, Zhao Y, Wang Y, Fei J, Niu Z, Dong X, Wang X, Liu B, Li H, Hao X, Zhao Y
Heliyon 2022 Oct;8(10):e11179

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Oleuropein ameliorated lung ischemia-reperfusion injury by inhibiting TLR4 signaling cascade in alveolar macrophages.

Xu Z, Sun X, Ding B, Zi M, Ma Y
Transplant immunology 2022 Oct;74:101664

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EphA4 regulates white matter remyelination after ischemic stroke through Ephexin-1/RhoA/ROCK signaling pathway.

Liu C, Han S, Zheng J, Wang H, Li S, Li J
Glia 2022 Oct;70(10):1971-1991

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TCF3 protein was highly expressed in pediatric Burkitt lymphoma and predicts poor prognosis: a single-center study.

Man J, Wang H, Qian X, Chen L, Ma Y, Qian M, Zhai X
Leukemia & lymphoma 2022 Oct;63(10):2453-2460

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A Dual-Action Molecule Suppresses S. aureus Infection as an Inhibitor Targeting Hla Pore Formation and TLR2 Signaling.

Wang T, Jiang F, Su J, Chu X, Cao Y, Lv H, Deng X, Wang J
Advanced biology 2022 Oct;6(10):e2200109

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GDNF Promotes Astrocyte Abnormal Proliferation and Migration Through the GFRα1/RET/MAPK/pCREB/LOXL2 Signaling Axis.

Wang M, Han X, Zha W, Wang X, Liu L, Li Z, Shi Y, Kan X, Wang G, Gao D, Zhang B
Molecular neurobiology 2022 Oct;59(10):6321-6340

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Impact of Resolvin D1 on the inflammatory phenotype of periodontal ligament cell response to hypoxia.

Cai J, Liu J, Yan J, Lu X, Wang X, Li S, Mustafa K, Wang H, Xue Y, Mustafa M, Kantarci A, Xing Z
Journal of periodontal research 2022 Oct;57(5):1034-1042

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PGC-1α attenuates TNF-α-induced inflammatory responses in OCCM-30 cells.

Fu Y, Du M, Cao Z, He H
Journal of periodontal research 2022 Oct;57(5):1024-1033

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Quercetin in Tonglong Qibi decoction ameliorates testosterone-induced benign prostatic hyperplasia in rats by regulating Nrf2 signalling pathways and oxidative stress.

Fu W, Chen S, Zhang Z, Chen Y, You X, Li Q
Andrologia 2022 Oct;54(9):e14502

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The c.612A>G mutation of MC4R affects constitutive activity and signaling in domestic goats.

Yan Y, Chi S, Liu G, Huang Y, Pan D, Jiang X
Animal genetics 2022 Oct;53(5):665-675

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Catalpol Exerts Antidepressant-Like Effects by Enhancing Anti-oxidation and Neurotrophy and Inhibiting Neuroinflammation via Activation of HO-1.

Wu X, Liu C, Wang J, Guan Y, Song L, Chen R, Gong M
Neurochemical research 2022 Oct;47(10):2975-2991

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Proteasomal deubiquitylase activity enhances cell surface recycling of the epidermal growth factor receptor in non-small cell lung cancer.

Wang S, Wang T, Yang Q, Cheng S, Liu F, Yang G, Wang F, Wang R, Yang D, Zhou M, Duan C, Zhang Y, Liu H, Dai Z, Tian K, Liu S
Cellular oncology (Dordrecht, Netherlands) 2022 Oct;45(5):951-965

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Effect of the Pulsed Electromagnetic Field Treatment in a Rat Model of Senile Osteoporosis In Vivo.

Zhou J, Wang J, Qu M, Huang X, Yin L, Liao Y, Huang F, Ning P, Zhong P, Zeng Y
Bioelectromagnetics 2022 Oct;43(7):438-447

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Inducement of ER Stress by PAD Inhibitor BB-Cl-Amidine to Effectively Kill AML Cells.

Sun YN, Ma YN, Jia XQ, Yao Q, Chen JP, Li H
Current medical science 2022 Oct;42(5):958-965

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Network pharmacology and molecular docking study on the effect of Kaempferol in treatment of metabolic associated fatty liver disease.

Kaixuan Z, Dong Z, Huiwei B, Lijing LI
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Oct;42(5):788-794

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Ultrasound-based radiomics for the evaluation of fetal rat lung maturity: A noninvasive assessment method (Ultrasound-based radiomics in fetal rat lung).

Du Y, Jiao J, Cao A, Ji C, Li M, Ji C, Wu Y, Guo Y, Wang Y, Zhou J, Ren Y
Prenatal diagnosis 2022 Oct;42(11):1429-1437

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Sestrin2 attenuates renal damage by regulating Hippo pathway in diabetic nephropathy.

Bian Y, Shi C, Song S, Mu L, Wu M, Qiu D, Dong J, Zhang W, Yuan C, Wang D, Zhou Z, Dong X, Shi Y
Cell and tissue research 2022 Oct;390(1):93-112

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Hepatic cytokine-inducible SH2-containing protein (CISH) regulates gluconeogenesis via cAMP-responsive element binding protein (CREB).

Xiao F, Deng J, Jiao F, Hu X, Jiang H, Yuan F, Chen S, Niu Y, Jiang X, Guo F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Oct;36(10):e22541

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Bryodulcosigenin attenuates bleomycin-induced pulmonary fibrosis via inhibiting AMPK-mediated mesenchymal epithelial transition and oxidative stress.

Ding Y, Wang L, Liu B, Ren G, Okubo R, Yu J, Zhang C
Phytotherapy research : PTR 2022 Oct;36(10):3911-3923

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MicroRNA-124 attenuates PTSD-like behaviors and reduces the level of inflammatory cytokines by downregulating the expression of TRAF6 in the hippocampus of rats following single-prolonged stress.

Chen Y, An Q, Yang ST, Chen YL, Tong L, Ji LL
Experimental neurology 2022 Oct;356:114154

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Depression compromises antiviral innate immunity via the AVP-AHI1-Tyk2 axis.

Zhang HG, Wang B, Yang Y, Liu X, Wang J, Xin N, Li S, Miao Y, Wu Q, Guo T, Yuan Y, Zuo Y, Chen X, Ren T, Dong C, Wang J, Ruan H, Sun M, Xu X, Zheng H
Cell research 2022 Oct;32(10):897-913

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Proteasomal degradation of WT proinsulin in pancreatic beta cells.

Xu X, Arunagiri A, Haataja L, Alam M, Ji S, Qi L, Tsai B, Liu M, Arvan P
The Journal of biological chemistry 2022 Oct;298(10):102406

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Proto-oncogene FAM83A contributes to casein kinase 1-mediated mitochondrial maintenance and white adipocyte differentiation.

Huang K, Jia Z, Li H, Peng Y, Chen X, Luo N, Song T, Wang Y, Shi X, Kuang S, Yang G
The Journal of biological chemistry 2022 Oct;298(10):102339

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ATG4B hinders porcine epidemic diarrhea virus replication through interacting with TRAF3 and activating type-I IFN signaling.

Dong S, Kong N, Qin W, Zhai H, Zhai X, Yang X, Ye C, Ye M, Liu C, Yu L, Zheng H, Tong W, Yu H, Zhang W, Li Y, Tong G, Shan T
Veterinary microbiology 2022 Oct;273:109544

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IL-1β induced by PRRSV co-infection inhibited CSFV C-strain proliferation via the TLR4/NF-κB/MAPK pathways and the NLRP3 inflammasome.

Chen D, Xu S, Jiang R, Guo Y, Yang X, Zhang Y, Zhou L, Ge X, Han J, Guo X, Yang H
Veterinary microbiology 2022 Oct;273:109513

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Pharmacologic inhibition of LAT1 predominantly suppresses transport of large neutral amino acids and downregulates global translation in cancer cells.

Nishikubo K, Ohgaki R, Okanishi H, Okuda S, Xu M, Endou H, Kanai Y
Journal of cellular and molecular medicine 2022 Oct;26(20):5246-5256

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MiR-574-5p promotes cell proliferation by negatively regulating small C-terminal domain phosphatase 1 in esophageal squamous cell carcinoma.

Zhao C, Liu J, Xu Y, Guo J, Wang L, Chen L, Xu L, Dong G, Zheng W, Li Z, Cai H, Li S
Iranian journal of basic medical sciences 2022 Oct;25(10):1243-1250

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Cold exposure-induced endoplasmic reticulum stress regulates autophagy through the SIRT2/FoxO1 signaling pathway.

Guo J, Nie J, Chen Z, Wang X, Hu H, Xu J, Lu J, Ma L, Ji H, Yuan J, Xu B
Journal of cellular physiology 2022 Oct;237(10):3960-3970

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Inka2, a novel Pak4 inhibitor, regulates actin dynamics in neuronal development.

Yamada S, Mizukoshi T, Tokunaga A, Sakakibara SI
PLoS genetics 2022 Oct;18(10):e1010438

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Schisantherin D from Schisandra chinensis (Turcz.) Baill. exhibits anti-liver fibrosis capacity via modulating ETBR involved signaling, an in vitro and in vivo study.

Li C, Ru YJ, Lin QY, Gao GC, Yang YD, Zhang XQ, Gao JL, Liu SH, Zheng CW, Wang L, Zheng YX, Wu JM
Fitoterapia 2022 Oct;162:105290

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Apelin-13 attenuates depressive-like behaviors induced by chronic unpredictable mild stress via activating AMPK/PGC-1α/FNDC5/BDNF pathway.

Hu S, He L, Chen B, You Y
Peptides 2022 Oct;156:170847

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Babao Dan inhibits lymphangiogenesis of gastric cancer in vitro and in vivo via lncRNA-ANRIL/VEGF-C/VEGFR-3 signaling axis.

Guan J, Guan B, Shang H, Peng J, Yang H, Lin J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113630

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Fucoidan inhibits EGFR redistribution and potentiates sorafenib to overcome sorafenib-resistant hepatocellular carcinoma.

Luo J, Li L, Zhu Z, Chang B, Deng F, Wang D, Lu X, Zuo D, Chen Q, Zhou J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113602

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Gegen Qinlian decoction ameliorates murine colitis by inhibiting the expansion of Enterobacteriaceae through activating PPAR-γ signaling.

Hu J, Tong Y, Shen Z, Li Y, Cheng C, Au R, Xu F, Liu Y, Zhu L, Shen H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113571

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Identification by RNA-Seq of let-7 clusters as prenatal biomarkers for nonsyndromic cleft lip with palate.

Jia S, Zhang Q, Wang Y, Wei X, Gu H, Liu D, Ma W, He Y, Luo W, Yuan Z
Annals of the New York Academy of Sciences 2022 Oct;1516(1):234-246

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LncRNA LINC00281/Annexin A2 Regulates Vascular Smooth Muscle Cell Phenotype Switching via the Nuclear Factor-Kappa B Signaling Pathway.

Cheng L, Wang H, Maboh R, Mao G, Wu X, Chen H
Journal of cardiovascular translational research 2022 Oct;15(5):971-984

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Lithocarpus polystachyus (Sweet Tea) water extract promotes human hepatocytes HL7702 proliferation through activation of HGF/AKT/ERK signaling pathway.

Lei M, Chen N, Xu Y, Gong Q, Gao J
Chinese herbal medicines 2022 Oct;14(4):576-582

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VCAM-1-binding peptide targeted cationic liposomes containing NLRP3 siRNA to modulate LDL transcytosis as a novel therapy for experimental atherosclerosis.

Jia X, Bai X, Yang X, Wang L, Lu Y, Zhu L, Zhao Y, Cheng W, Shu M, Mei Q, Jin S
Metabolism: clinical and experimental 2022 Oct;135:155274

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Triclocarban evoked neutrophil extracellular trap formation in common carp (Cyprinus carpio L.) by modulating SIRT3-mediated ROS crosstalk with ERK1/2/p38 signaling.

Li S, Wang Y, Yu D, Zhang Y, Wang X, Shi M, Xiao Y, Li X, Xiao H, Chen L, Xiong X
Fish & shellfish immunology 2022 Oct;129:85-95

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Synthesis and anti-inflammatory activity of paeonol derivatives with etherized aryl urea by regulating TLR4/MyD88 signaling pathway in RAW264.7 cell.

Gong X, He Y, Yang D, Yang S, Li J, Zhao H, Chen Q, Ren Q, Zhang B
Bioorganic chemistry 2022 Oct;127:105939

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Hoxa9/meis1-transgenic zebrafish develops acute myeloid leukaemia-like disease with rapid onset and high penetrance.

Wang W, Li H, Huang M, Wang X, Li W, Qian X, Jing L
Open biology 2022 Oct;12(10):220172

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Acadesine alleviates acute pancreatitis-related lung injury by mediating the barrier protective function of pulmonary microvascular endothelial cells.

Zhu X, Duan F, Zhang Y, Wang X, Wang Y, Chen J, Zhang L, Wu M, Pan Z, Chen B
International immunopharmacology 2022 Oct;111:109165

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Eupalinolide B attenuates lipopolysaccharide-induced acute lung injury through inhibition of NF-κB and MAPKs signaling by targeting TAK1 protein.

Yang L, Chen H, Hu Q, Liu L, Yuan Y, Zhang C, Tang J, Shen X
International immunopharmacology 2022 Oct;111:109148

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SCO-spondin-derived peptide NX210 rescues neurons from cerebral ischemia/reperfusion injury through modulating the Integrin-β1 mediated PI3K/Akt pathway.

Yang L, Zhu J, Yang L, Gan Y, Hu D, Zhao J, Zhao Y
International immunopharmacology 2022 Oct;111:109079

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High-throughput membrane-anchored proteome screening reveals PIEZO1 as a promising antibody-drug target for human esophageal squamous cell carcinoma.

Qin X, Ni Z, Jiang J, Liu X, Dong X, Li M, Miao K, Rao S, Zhang W, Cai K
Cancer medicine 2022 Oct;11(19):3700-3713

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Ginseng under forest exerts stronger anti-aging effects compared to garden ginseng probably via regulating PI3K/AKT/mTOR pathway, SIRT1/NF-κB pathway and intestinal flora.

Hao M, Ding C, Peng X, Chen H, Dong L, Zhang Y, Chen X, Liu W, Luo Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Oct;105:154365

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Ban-xia-xie-xin-tang ameliorates hepatic steatosis by regulating Cidea and Cidec expression in HFD-fed mice.

Xia QS, Gao Y, Wen-Bin W, Wu F, Dong H, Xu LJ, Fang K, Hu ML, Yuan F, Lu FE, Gong J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Oct;105:154351

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Deletion of Smurf1 attenuates liver steatosis via stabilization of p53.

Lin W, Zhang X, Zhang C, Li L, Zhang J, Xie P, Zhan Y, An W
Laboratory investigation; a journal of technical methods and pathology 2022 Oct;102(10):1075-1087

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Structure-based discovery of Licoflavone B and Ginkgetin targeting c-Myc G-quadruplex to suppress c-Myc transcription and myeloma growth.

Liu L, Geng X, Zhang J, Li S, Gao J
Chemical biology & drug design 2022 Oct;100(4):525-533

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Downregulation of exosomal miR-7-5p promotes breast cancer migration and invasion by targeting RYK and participating in the atypical WNT signalling pathway.

Liang Z, Liu L, Gao R, Che C, Yang G
Cellular & molecular biology letters 2022 Oct 9;27(1):88

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CXCL12/CXCR7/β-arrestin1 biased signal promotes epithelial-to-mesenchymal transition of colorectal cancer by repressing miRNAs through YAP1 nuclear translocation.

Si M, Song Y, Wang X, Wang D, Liu X, Qu X, Song Z, Yu X
Cell & bioscience 2022 Oct 9;12(1):171

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Up-regulation of miR-133a-3p promotes ovary insulin resistance on granulosa cells of obese PCOS patients via inhibiting PI3K/AKT signaling.

Yang X, Wang K, Lang J, Guo D, Gao H, Qiu Y, Jin X, Zhang M, Shi J, Ma Q, Ma Q, Wen Z
BMC women's health 2022 Oct 8;22(1):412

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Gandouling Mitigates CuSO(4)-Induced Heart Injury in Rats.

Fang S, Yang W, Zhang K, Peng C
Animals : an open access journal from MDPI 2022 Oct 8;12(19)

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Progesterone Induces Apoptosis and Steroidogenesis in Porcine Placental Trophoblasts.

Liu Y, Ding H, Yang Y, Liu Y, Cao X, Feng T
Animals : an open access journal from MDPI 2022 Oct 8;12(19)

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ZIP1(+) fibroblasts protect lung cancer against chemotherapy via connexin-43 mediated intercellular Zn(2+) transfer.

Ni C, Lou X, Yao X, Wang L, Wan J, Duan X, Liang J, Zhang K, Yang Y, Zhang L, Sun C, Li Z, Wang M, Zhu L, Lv D, Qin Z
Nature communications 2022 Oct 7;13(1):5919

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Protein disulfide isomerase blocks the interaction of LC3II-PHB2 and promotes mTOR signaling to regulate autophagy and radio/chemo-sensitivity.

Wang R, Shang Y, Chen B, Xu F, Zhang J, Zhang Z, Zhao X, Wan X, Xu A, Wu L, Zhao G
Cell death & disease 2022 Oct 6;13(10):851

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Exploring the protective mechanisms of total tannins from Geum japonicum var. chinense F.Bolle in mice with hematopoietic dysfunction via the JAK2/STAT3/5 signaling pathway.

Mu W, Ao J, Li Y, Zhang J, Duan C
Journal of ethnopharmacology 2022 Oct 5;296:115507

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Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation.

Wang Y, Karki R, Mall R, Sharma BR, Kalathur RC, Lee S, Kancharana B, So M, Combs KL, Kanneganti TD
Cell reports 2022 Oct 4;41(1):111434

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CTRP1 prevents high fat diet-induced obesity and improves glucose homeostasis in obese and STZ-induced diabetic mice.

Ren M, Pan J, Yu X, Chang K, Yuan X, Zhang C
Journal of translational medicine 2022 Oct 4;20(1):449

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Upregulation of CRABP2 by TET1-mediated DNA hydroxymethylation attenuates mitochondrial apoptosis and promotes oxaliplatin resistance in gastric cancer.

Tang X, Liang Y, Sun G, He Q, Hou Z, Jiang X, Gao P, Qu H
Cell death & disease 2022 Oct 4;13(10):848

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Z. morio Hemolymph Relieves E. coli-Induced Mastitis by Inhibiting Inflammatory Response and Repairing the Blood-Milk Barrier.

Zou Y, Wang X, Xu J, Wang S, Li S, Zhu Y, Wang J
International journal of molecular sciences 2022 Oct 31;23(21)

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Injectable and reactive oxygen species-scavenging gelatin hydrogel promotes neural repair in experimental traumatic brain injury.

Zhang D, Chang R, Ren Y, He Y, Guo S, Guan F, Yao M
International journal of biological macromolecules 2022 Oct 31;219:844-863

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Preparation of curcumin-loaded cochleates: characterisation, stability and antioxidant properties.

Chen L, Yue B, Liu Z, Luo Y, Ni L, Shen W, Zhou Z, Ge X
Food & function 2022 Oct 31;13(21):11273-11282

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Lysine acetylome profiling in mouse hippocampus and its alterations upon FMRP deficiency linked to abnormal energy metabolism.

Wu YY, Yang C, Yan HJ, Lu P, Zhang L, Feng WC, Long YS
Journal of proteomics 2022 Oct 30;269:104720

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Interferon-Inducible Transmembrane Protein 3 (IFITM3) Restricts Rotavirus Infection.

Pang Z, Hao P, Qu Q, Li L, Jiang Y, Xiao S, Jin N, Li C
Viruses 2022 Oct 30;14(11)

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VAMP4 regulates insulin levels by targeting secretory granules to lysosomes.

Li M, Feng F, Feng H, Hu P, Xue Y, Xu T, Song E
The Journal of cell biology 2022 Oct 3;221(10)

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Down-regulation of NR2B receptors contributes to the analgesic and antianxiety effects of enriched environment mediated by endocannabinoid system in the inflammatory pain mice.

Jiang S, Zheng C, Wen G, Bu B, Zhao S, Xu X
Behavioural brain research 2022 Oct 28;435:114062

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Srolo Bzhtang reduces inflammation and vascular remodeling via suppression of the MAPK/NF-κB signaling pathway in rats with pulmonary arterial hypertension.

Chen T, Su S, Yang Z, Zhang D, Li Z, Lu D
Journal of ethnopharmacology 2022 Oct 28;297:115572

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RTCB Complex Regulates Stress-Induced tRNA Cleavage.

Akiyama Y, Takenaka Y, Kasahara T, Abe T, Tomioka Y, Ivanov P
International journal of molecular sciences 2022 Oct 28;23(21)

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Auxin and abscisic acid antagonistically regulate ascorbic acid production via the SlMAPK8-SlARF4-SlMYB11 module in tomato.

Xu X, Zhang Q, Gao X, Wu G, Wu M, Yuan Y, Zheng X, Gong Z, Hu X, Gong M, Qi T, Li H, Luo Z, Li Z, Deng W
The Plant cell 2022 Oct 27;34(11):4409-4427

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Granulocytic MDSC with Deficient CCR5 Alleviates Lipogenesis and Inflammation in Nonalcoholic Fatty Liver Disease.

Liao TC, Huang JP, Tsai YT, Shih WC, Juan CC, Hsieh PS, Hung LM, Yu CL
International journal of molecular sciences 2022 Oct 27;23(21)

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Neuropilin-1 Facilitates Pseudorabies Virus Replication and Viral Glycoprotein B Promotes Its Degradation in a Furin-Dependent Manner.

Chen M, Wang MH, Shen XG, Liu H, Zhang YY, Peng JM, Meng F, Wang TY, Bai YZ, Sun MX, Tian ZJ, Yin X, Cai XH, Tang YD
Journal of virology 2022 Oct 26;96(20):e0131822

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Circ007071 Inhibits Unsaturated Fatty Acid Synthesis by Interacting with miR-103-5p to Enhance PPARγ Expression in the Dairy Goat Mammary Gland.

Chen Z, Lu Q, Zhang X, Zhang Z, Cao X, Wang K, Lu X, Yang Z, Loor JJ, Jiao P
Journal of agricultural and food chemistry 2022 Oct 26;70(42):13719-13729

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Fucosylated Chondroitin Sulfate against Parkinson's Disease through Inhibiting Inflammation Induced by Gut Dysbiosis.

Liu Y, Liu X, Ye Q, Wang Y, Zhang J, Lin S, Wang G, Yang X, Zhang J, Chen S, Wu N
Journal of agricultural and food chemistry 2022 Oct 26;70(42):13676-13691

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The oncoprotein MUC1 facilitates breast cancer progression by promoting Pink1-dependent mitophagy via ATAD3A destabilization.

Li Q, Chu Y, Li S, Yu L, Deng H, Liao C, Liao X, Yang C, Qi M, Cheng J, Chen G, Huang L
Cell death & disease 2022 Oct 26;13(10):899

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METTL3 acetylation impedes cancer metastasis via fine-tuning its nuclear and cytosolic functions.

Li Y, He X, Lu X, Gong Z, Li Q, Zhang L, Yang R, Wu C, Huang J, Ding J, He Y, Liu W, Chen C, Cao B, Zhou D, Shi Y, Chen J, Wang C, Zhang S, Zhang J, Ye J, You H
Nature communications 2022 Oct 26;13(1):6350

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Environmentally-relevant concentrations of the antipsychotic drugs sulpiride and clozapine induce abnormal dopamine and serotonin signaling in zebrafish brain.

Zhang B, Peng X, Sun X, Guo Y, Li T
Scientific reports 2022 Oct 26;12(1):17973

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Docetaxel-resistant triple-negative breast cancer cell-derived exosomal lncRNA LINC00667 reduces the chemosensitivity of breast cancer cells to docetaxel via targeting miR-200b-3p/Bcl-2 axis.

Li J, Kang J, Liu W, Liu J, Pan G, Mao A, Zhang Q, Lu J, Ding J, Li H
European journal of histochemistry : EJH 2022 Oct 25;66(4)

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SLC38A6, regulated by EP300-mediated modifications of H3K27ac, promotes cell proliferation, glutamine metabolism and mitochondrial respiration in hepatocellular carcinoma.

Huang L, Li L, Cheng B, Xing T
Carcinogenesis 2022 Oct 22;43(9):885-894

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The necroptosis-inducing pseudokinase mixed lineage kinase domain-like regulates the adipogenic differentiation of pre-adipocytes.

Magusto J, Beaupère C, Afonso MB, Auclair M, Delaunay JL, Soret PA, Courtois G, Aït-Slimane T, Housset C, Jéru I, Fève B, Ratziu V, Rodrigues CMP, Gautheron J
iScience 2022 Oct 21;25(10):105166

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Vascular restenosis reduction with platelet membrane coated nanoparticle directed M2 macrophage polarization.

Li F, Rong Z, Zhang R, Niu S, Di X, Ni L, Liu C
iScience 2022 Oct 21;25(10):105147

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Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration.

Tian H, Chen Z, Zhu X, Ou Q, Wang Z, Wu B, Xu JY, Jin C, Gao F, Wang J, Zhang J, Zhang J, Lu L, Xu GT
iScience 2022 Oct 21;25(10):105050

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Histone methyltransferase Smyd2 drives adipogenesis via regulating STAT3 phosphorylation.

Su H, Meng C, Xu J, Su Z, Xiao C, Yang D
Cell death & disease 2022 Oct 21;13(10):890

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Argininosuccinate lyase drives activation of mutant TERT promoter in glioblastomas.

Shi Z, Ge X, Li M, Yin J, Wang X, Zhang J, Chen D, Li X, Wang X, Ji J, You Y, Qian X
Molecular cell 2022 Oct 20;82(20):3919-3931.e7

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In Vitro and In Vivo Evaluation of Antidiabetic Properties and Mechanisms of Ficus tikoua Bur.

Wang H, Zhang K, Chen X, Han M, Lu J, Zhang Y
Nutrients 2022 Oct 20;14(20)

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Proteomic analysis reveals zinc-finger CCHC-type containing protein 3 as a factor inhibiting virus infection by promoting innate signaling.

Chen X, Li Z, Wang S, Tong G, Chen K, Zhao Y
Virus research 2022 Oct 2;319:198876

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Astragalus polysaccharide alleviated the inhibition of CSFV C-strain replication caused by PRRSV via the TLRs/NF‑κB/TNF-α pathways.

Chen D, Kang H, Tuo T, Wang L, Xia Y, Zhang Y, Zhou L, Ge X, Han J, Guo X, Yang H
Virus research 2022 Oct 2;319:198854

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SOX2 Promotes Invasion in Human Bladder Cancers through MMP2 Upregulation and FOXO1 Downregulation.

Xie Q, Hua X, Huang C, Liao X, Tian Z, Xu J, Zhao Y, Jiang G, Huang H, Huang C
International journal of molecular sciences 2022 Oct 19;23(20)

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High RAS-related protein Rab-7a (RAB7A) expression is a poor prognostic factor in pancreatic adenocarcinoma.

Liu Q, Bai Y, Shi X, Guo D, Wang Y, Wang Y, Guo WZ, Zhang S
Scientific reports 2022 Oct 19;12(1):17492

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Artemisia sphaerocephala Krasch polysaccharide promotes adipose thermogenesis and decreases obesity by shaping the gut microbiota.

Zeng X, Ren D, Li D, Du H, Yang X
Food & function 2022 Oct 17;13(20):10651-10664

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PCSK9 promotes the progression and metastasis of colon cancer cells through regulation of EMT and PI3K/AKT signaling in tumor cells and phenotypic polarization of macrophages.

Wang L, Li S, Luo H, Lu Q, Yu S
Journal of experimental & clinical cancer research : CR 2022 Oct 14;41(1):303

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Inhibition of LSD1 with Bomedemstat Sensitizes Small Cell Lung Cancer to Immune Checkpoint Blockade and T-Cell Killing.

Hiatt JB, Sandborg H, Garrison SM, Arnold HU, Liao SY, Norton JP, Friesen TJ, Wu F, Sutherland KD, Rienhoff HY, Martins R, Houghton AM, Srivastava S, MacPherson D
Clinical cancer research : an official journal of the American Association for Cancer Research 2022 Oct 14;28(20):4551-4564

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Structural analysis of the overoxidized Cu/Zn-superoxide dismutase in ROS-induced ALS filament formation.

Baek Y, Woo TG, Ahn J, Lee D, Kwon Y, Park BJ, Ha NC
Communications biology 2022 Oct 12;5(1):1085

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LncGSAR Controls Ovarian Granulosa Cell Steroidogenesis via Sponging MiR-125b to Activate SCAP/SREBP Pathway.

Wang Y, Guo Y, Duan C, Li J, Ji S, Yan H, Liu Y, Zhang Y
International journal of molecular sciences 2022 Oct 12;23(20)

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The Effect of Circumscribed Exposure to the Pan-Aurora Kinase Inhibitor VX-680 on Proliferating Euploid Cells.

Liu X, Shi Q, Choudhry N, Zhang T, Liu H, Zhang S, Zhang J, Yang D
International journal of molecular sciences 2022 Oct 11;23(20)

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Cortisol Stimulates Local Progesterone Withdrawal Through Induction of AKR1C1 in Human Amnion Fibroblasts at Parturition.

Lu JW, Lei WJ, Ling LJ, Wang LY, Lin YK, Zhang F, Li MD, Pan F, Wang WS, Sun K
Endocrinology 2022 Oct 11;163(11)

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Characterizing and Targeting Genes Regulated by Transcription Factor MYBL2 in Lung Adenocarcinoma Cells.

Lee Y, Wu Z, Yang S, Schreiner SM, Gonzalez-Smith LD, Rhie SK
Cancers 2022 Oct 11;14(20)

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mTORC1 signaling pathway integrates estrogen and growth factor to coordinate vaginal epithelial cells proliferation and differentiation.

Wan S, Sun Y, Fu J, Song H, Xiao Z, Yang Q, Wang S, Yu G, Feng P, Lv W, Luo L, Guan Z, Liu F, Zhou Q, Yin Z, Yang M
Cell death & disease 2022 Oct 11;13(10):862

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CGG repeat expansion in NOTCH2NLC causes mitochondrial dysfunction and progressive neurodegeneration in Drosophila model.

Yu J, Liufu T, Zheng Y, Xu J, Meng L, Zhang W, Yuan Y, Hong D, Charlet-Berguerand N, Wang Z, Deng J
Proceedings of the National Academy of Sciences of the United States of America 2022 Oct 11;119(41):e2208649119

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Stain-Free total-protein normalization enhances the reproducibility of Western blot data.

Maloy A, Alexander S, Andreas A, Nyunoya T, Chandra D
Analytical biochemistry 2022 Oct 1;654:114840

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Siah1 promotes the proliferation of NSCLC cells through ubiquitinating and stabilizing Notch1.

Liu Y, Li Q, Geng L, Zhou X, Zhou X, Dong Y, Zhang Y
Experimental cell research 2022 Oct 1;419(1):113305

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Exosomal circRNA Scm-like with four malignant brain tumor domains 2 (circ-SFMBT2) enhances the docetaxel resistance of prostate cancer via the microRNA-136-5p/tribbles homolog 1 pathway.

Tan X, Song X, Fan B, Li M, Zhang A, Pei L
Anti-cancer drugs 2022 Oct 1;33(9):871-882

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Effect of muscone on anti-apoptotic ability of muskrat prostate primary cells.

Zhang Y, Zhao X, Man X, Ma Y, Zhang W, Wang Y, Lei X, Bai S
American journal of physiology. Regulatory, integrative and comparative physiology 2022 Oct 1;323(4):R571-R580

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lncRNA UCA1 induces autophagic gene expression via epigenetic regulation mediated by ATG16L1 and miR-132-3p in SH-SY5Y cells treated with retinoic acid.

Wen F, Zhan Q, Zou T, Tan ZG, Xiang J
Epileptic disorders : international epilepsy journal with videotape 2022 Oct 1;24(5):917-927

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β-Arrestin2-biased Drd2 agonist UNC9995 alleviates astrocyte inflammatory injury via interaction between β-arrestin2 and STAT3 in mouse model of depression.

Liu Y, Song N, Yao H, Jiang S, Wang Y, Zheng Y, Zhou Y, Ding J, Hu G, Lu M
Journal of neuroinflammation 2022 Oct 1;19(1):240

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Advanced glycation end products induce Aβ(1-42) deposition and cognitive decline through H19/miR-15b/BACE1 axis in diabetic encephalopathy.

Jiang L, Yuan N, Zhao N, Tian P, Zhang D, Qin Y, Shi Z, Gao Z, Zhang N, Zhou H, Zhang R, Xu S
Brain research bulletin 2022 Oct 1;188:187-196

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Inactivation of fatty acid amide hydrolase protects against ischemic reperfusion injury-induced renal fibrogenesis.

Chen C, Wang W, Poklis JL, Lichtman AH, Ritter JK, Hu G, Xie D, Li N
Biochimica et biophysica acta. Molecular basis of disease 2022 Oct 1;1868(10):166456

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Role of estrogen receptors in thyroid toxicity induced by mono (2-ethylhexyl) phthalate via endoplasmic reticulum stress: An in vitro mechanistic investigation.

Xu Q, Zhou L, Ri H, Li X, Zhang X, Qi W, Ye L
Environmental toxicology and pharmacology 2022 Nov;96:104007

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SARS-CoV-2 ORF10 antagonizes STING-dependent interferon activation and autophagy.

Han L, Zheng Y, Deng J, Nan ML, Xiao Y, Zhuang MW, Zhang J, Wang W, Gao C, Wang PH
Journal of medical virology 2022 Nov;94(11):5174-5188

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Plasma exosomal miR-122 regulates the efficacy of metformin via AMPK in type 2 diabetes and hepatocellular carcinoma.

Peng H, Hou M, Wu Z, Wang J, Zhou M, Zhuang X, Xing J, Tao Q, Huang L, Zhou F, Zhang S, Feng Q, Hou Y, Yu Q
Heliyon 2022 Nov;8(11):e11503

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Carboxylesterase 2 induces mitochondrial dysfunction via disrupting lipid homeostasis in oral squamous cell carcinoma.

Chen X, Liu Q, Chen Y, Wang L, Yang R, Zhang W, Pan X, Zhang S, Chen C, Wu T, Xia J, Cheng B, Chen X, Ren X
Molecular metabolism 2022 Nov;65:101600

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CCT4 knockdown enhances the sensitivity of cisplatin by inhibiting glycolysis in human esophageal squamous cell carcinomas.

Fang J, Ma Y, Li Y, Li J, Zhang X, Han X, Ma S, Guan F
Molecular carcinogenesis 2022 Nov;61(11):1043-1055

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Mutations in GCK May Lead to MODY2 by Reducing Glycogen Synthesis.

Li Z, Li K, Sun Y, Jiang X, Liu J, Li J, Fang L, Li G, Guan Q, Xu C
Advanced biology 2022 Nov;6(11):e2200097

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Ergosterol increases 7-dehydrocholesterol, a cholesterol precursor, and decreases cholesterol in human HepG2 cells.

Kuwabara N, Ohta-Shimizu M, Fuwa F, Tomitsuka E, Sato S, Nakagawa S
Lipids 2022 Nov;57(6):303-311

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NINJ1 triggers extravillous trophoblast cell dysfunction through blocking the STAT3 signaling pathway.

Zhang X, Chen Y, Wang X, Zhang Z, Wang J, Shen Y, Hu Y, Wu X
Genes & genomics 2022 Nov;44(11):1385-1397

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AIMP1 promotes multiple myeloma malignancy through interacting with ANP32A to mediate histone H3 acetylation.

Wei R, Zhu Y, Zhang Y, Zhao W, Yu X, Wang L, Gu C, Gu X, Yang Y
Cancer communications (London, England) 2022 Nov;42(11):1185-1206

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Targeting epiregulin in the treatment-damaged tumor microenvironment restrains therapeutic resistance.

Wang C, Long Q, Fu Q, Xu Q, Fu D, Li Y, Gao L, Guo J, Zhang X, Lam EW, Campisi J, Sun Y
Oncogene 2022 Nov;41(45):4941-4959

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Repurposing an Antiepileptic Drug for the Treatment of Glioblastoma.

Yadav A, Alnakhli A, Vemana HP, Bhutkar S, Muth A, Dukhande VV
Pharmaceutical research 2022 Nov;39(11):2871-2883

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Cancer-associated fibroblast-secreted miR-421 promotes pancreatic cancer by regulating the SIRT3/H3K9Ac/HIF-1α axis.

Zhou B, Lei JH, Wang Q, Qu TF, Cha LC, Zhan HX, Liu SL, Hu X, Sun CD, Guo WD, Qiu FB, Cao JY
The Kaohsiung journal of medical sciences 2022 Nov;38(11):1080-1092

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Disturbing NLRP3 acetylation and inflammasome assembly inhibits androgen receptor-promoted inflammatory responses and prostate cancer progression.

Zhao AN, Yang Z, Wang DD, Shi B, Zhang H, Bai Y, Yan BW, Zhang Y, Wen JK, Wang XL, Qu CB
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Nov;36(11):e22602

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Total flavonoids from the dried root of Tetrastigma hemsleyanum Diels et Gilg inhibit colorectal cancer growth through PI3K/AKT/mTOR signaling pathway.

Zhai Y, Sun J, Sun C, Zhao H, Li X, Yao J, Su J, Xu X, Xu X, Hu J, Daglia M, Han B, Kai G
Phytotherapy research : PTR 2022 Nov;36(11):4263-4277

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Wogonoside attenuates liver fibrosis by triggering hepatic stellate cell ferroptosis through SOCS1/P53/SLC7A11 pathway.

Liu G, Wei C, Yuan S, Zhang Z, Li J, Zhang L, Wang G, Fang L
Phytotherapy research : PTR 2022 Nov;36(11):4230-4243

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The role of reelin in the pathological mechanism of depression from clinical to rodents.

Jin K, Zhang S, Jiang C, Liu R, Chen B, Zhao H, Zhang Q, Shen Z, Xu P, Hu X, Jiao J, Lu J, Huang M
Psychiatry research 2022 Nov;317:114838

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Specific targeting of glioblastoma with an oncolytic virus expressing a cetuximab-CCL5 fusion protein via innate and adaptive immunity.

Tian L, Xu B, Chen Y, Li Z, Wang J, Zhang J, Ma R, Cao S, Hu W, Chiocca EA, Kaur B, Caligiuri MA, Yu J
Nature cancer 2022 Nov;3(11):1318-1335

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Atg6 promotes organismal health by suppression of cell stress and inflammation.

Shen JL, Doherty J, Allen E, Fortier TM, Baehrecke EH
Cell death and differentiation 2022 Nov;29(11):2275-2287

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Wnt/beta-catenin signaling confers ferroptosis resistance by targeting GPX4 in gastric cancer.

Wang Y, Zheng L, Shang W, Yang Z, Li T, Liu F, Shao W, Lv L, Chai L, Qu L, Xu Q, Du J, Liang X, Zeng J, Jia J
Cell death and differentiation 2022 Nov;29(11):2190-2202

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PTX3 mediates the infiltration, migration, and inflammation-resolving-polarization of macrophages in glioblastoma.

Zhang H, Wang Y, Zhao Y, Liu T, Wang Z, Zhang N, Dai Z, Wu W, Cao H, Feng S, Zhang L, Cheng Q, Liu Z
CNS neuroscience & therapeutics 2022 Nov;28(11):1748-1766

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KLF16 inhibits PEDV replication by activating the type I IFN signaling pathway.

Dong S, Kong N, Shen H, Li Y, Qin W, Zhai H, Zhai X, Yang X, Ye C, Ye M, Liu C, Yu L, Zheng H, Tong W, Yu H, Zhang W, Tong G, Shan T
Veterinary microbiology 2022 Nov;274:109577

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LOC102553417 silencing facilitates the apoptosis of hepatic stellate cells via the miR‑30e/MTDH axis.

Wei W, Lin C, Hu R, Huang J, Chen X, Zhou L, Wei J, Deng YB, Wang CF
Molecular medicine reports 2022 Nov;26(5)

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IL-17A promotes lung fibrosis through impairing mitochondrial homeostasis in type II alveolar epithelial cells.

Xiao H, Peng L, Jiang D, Liu Y, Zhu L, Li Z, Geng J, Xie B, Huang X, Wang J, Dai H, Wang C
Journal of cellular and molecular medicine 2022 Nov;26(22):5728-5741

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High expression of HOXA4 in patients with glioma indicates unfavorable clinical outcomes.

Yu Z, Liu Z, Lian X, Cheng X, Liu B, Zhang B, Wang H, Wang J, Li A, Ren Z, Pang B, Qian R, Gao Y
Cell cycle (Georgetown, Tex.) 2022 Nov;21(22):2387-2402

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A single N6-methyladenosine site regulates lncRNA HOTAIR function in breast cancer cells.

Porman AM, Roberts JT, Duncan ED, Chrupcala ML, Levine AA, Kennedy MA, Williams MM, Richer JK, Johnson AM
PLoS biology 2022 Nov;20(11):e3001885

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Intermittent fasting protects against Alzheimer's disease in mice by altering metabolism through remodeling of the gut microbiota.

Pan RY, Zhang J, Wang J, Wang Y, Li Z, Liao Y, Liao Y, Zhang C, Liu Z, Song L, Yu J, Yuan Z
Nature aging 2022 Nov;2(11):1024-1039

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Small immune effectors coordinate peptidoglycan-derived immunity to regulate intestinal bacteria in shrimp.

Liu PP, Wei Z, Cheng ZH, Wang XW
PLoS pathogens 2022 Nov;18(11):e1010967

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Si-Wu-Tang ameliorates bile duct ligation-induced liver fibrosis via modulating immune environment.

Ma Z, Xue X, Bai J, Cai Y, Jin X, Jia K, Ding M, Lyu X, Li X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113834

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The dipeptidyl peptidase-4 inhibitor linagliptin ameliorates LPS-induced acute lung injury by maintenance of pulmonary microvascular barrier via activating the Epac1/AKT pathway.

Zhang N, Tang S, Zhang J, Pei B, Pang T, Sun G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113704

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B-cell receptor associated protein 31 deficiency decreases the expression of adhesion molecule CD11b/CD18 and PSGL-1 in neutrophils to ameliorate acute lung injury.

Li GX, Jiang XH, Zang JN, Zhu BZ, Jia CC, Niu KW, Liu X, Jiang R, Wang B
The international journal of biochemistry & cell biology 2022 Nov;152:106299

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LncRNA TM1-3P Regulates Proliferation, Apoptosis and Inflammation of Fibroblasts in Osteoarthritis through miR-144-3p/ONECUT2 Axis.

Yi Y, Yang N, Yang Z, Tao X, Li Y
Orthopaedic surgery 2022 Nov;14(11):3078-3091

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A novel ceRNA regulatory network involving the long noncoding NEAT1, miRNA-466f-3p and its mRNA target in osteoblast autophagy and osteoporosis.

Zhao X, Zhao D, Geng B, Yaobin W, Xia Y
Journal of molecular medicine (Berlin, Germany) 2022 Nov;100(11):1629-1646

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Schisandra chinensis Lignans Exert Antidepressant Effects by Promoting BV2 Microglia Polarization toward the M2 Phenotype through the Activation of the Cannabinoid Receptor Type-2-Signal Transducer and Activator of Transcription 6 Pathway.

Wang J, Zhang G, Yang Y, Zhang X, Shi K, Zhang X, Yan T, Jia Y
Journal of agricultural and food chemistry 2022 Nov 9;70(44):14157-14169

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In Vivo Visualization of RNAi Efficiency Using a Pumilio/FBF Protein-Based Reporter.

Shi X, Hu C, Jiang Y, Lei Z, Zhang C, Zhang B, Wang F
Analytical chemistry 2022 Nov 8;94(44):15525-15533

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Increased joint loading induces subchondral bone loss of the temporomandibular joint via the RANTES-CCRs-Akt2 axis.

Feng SY, Lei J, Li YX, Shi WG, Wang RR, Yap AU, Wang YX, Fu KY
JCI insight 2022 Nov 8;7(21)

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Glucosamine delays the progression of osteoporosis in senile mice by promoting osteoblast autophagy.

Su W, Lv C, Huang L, Zheng X, Yang S
Nutrition & metabolism 2022 Nov 8;19(1):75

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E3 Ubiquitin Ligase FBXO3 Drives Neuroinflammation to Aggravate Cerebral Ischemia/Reperfusion Injury.

Gao Y, Xiao X, Luo J, Wang J, Peng Q, Zhao J, Jiang N, Zhao Y
International journal of molecular sciences 2022 Nov 7;23(21)

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UNC13D inhibits STING signaling by attenuating its oligomerization on the endoplasmic reticulum.

Song P, Yang W, Lou KF, Dong H, Zhang H, Wang B, Chen D
EMBO reports 2022 Nov 7;23(11):e55099

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TRIM50 promotes NLRP3 inflammasome activation by directly inducing NLRP3 oligomerization.

Lin Y, Lv X, Sun C, Sun Y, Yang M, Ma D, Jing W, Zhao Y, Cheng Y, Xuan H, Han L
EMBO reports 2022 Nov 7;23(11):e54569

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Kruppel-like factor 13 inhibits cell proliferation of gastric cancer by inducing autophagic degradation of β-catenin.

Ding Y, Xu Y, Fu Y, Zhang H, Zhao L, Fan X
Discover oncology 2022 Nov 6;13(1):121

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The tyrosine phosphorylation of GRK2 is responsible for activated D(2)R-mediated insulin resistance.

Gao Z, Min X, Kim KM, Liu H, Hu L, Wu C, Zhang X
Biochemical and biophysical research communications 2022 Nov 5;628:40-48

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Cadmium-induced apoptosis of Leydig cells is mediated by excessive mitochondrial fission and inhibition of mitophagy.

Yi L, Shang XJ, Lv L, Wang Y, Zhang J, Quan C, Shi Y, Liu Y, Zhang L
Cell death & disease 2022 Nov 5;13(11):928

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Defective Human SRP Induces Protein Quality Control and Triggers Stress Response.

Tikhonova EB, Gutierrez Guarnizo SA, Kellogg MK, Karamyshev A, Dozmorov IM, Karamysheva ZN, Karamyshev AL
Journal of molecular biology 2022 Nov 30;434(22):167832

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Metformin alleviates HFD-induced oxidative stress in hepatocyte via activating SIRT6/PGC-1α/ENDOG signaling.

Gao S, Yang Q, Liu Z, Kong W, Chen J, Li X, Peng Y, Bao M, Bian X, Zhang Y, Jiang Q, Li Z, Zhang Y, Yan F, Ye J
Clinical science (London, England : 1979) 2022 Nov 30;136(22):1711-1730

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Transcriptome Analysis of Protection by Dendrobium Nobile Alkaloids (DNLA) against Chronic Alcoholic Liver Injury in Mice.

Huang X, Yang S, Sun J, Li X, Zhou SY, Shi JS, Liu J, Wu Q
Biomedicines 2022 Nov 3;10(11)

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Tim-4 reprograms cholesterol metabolism to suppress antiviral innate immunity by disturbing the Insig1-SCAP interaction in macrophages.

Wang Y, Wang Y, Ding L, Ren X, Wang B, Wang L, Zhao S, Yue X, Wu Z, Li C, Liang X, Ma C, Gao L
Cell reports 2022 Nov 29;41(9):111738

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IPO7 Promotes Odontoblastic Differentiation and Inhibits Osteoblastic Differentiation Through Regulation of RUNX2 Expression and Translocation.

Zhang Y, Zhang H, Xiao Z, Yuan G, Yang G
Stem cells (Dayton, Ohio) 2022 Nov 29;40(11):1020-1030

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De novo pyrimidine synthesis fuels glycolysis and confers chemoresistance in gastric cancer.

He D, Chen M, Chang L, Gu J, Liu F, Gao X, Ruan Y
Cancer letters 2022 Nov 28;549:215837

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Pathological characterization of a novel mouse model expressing the PD-linked CHCHD2-T61I mutation.

Kee TR, Wehinger JL, Gonzalez PE, Nguyen E, McGill Percy KC, Khan SA, Chaput D, Wang X, Liu T, Kang DE, Woo JA
Human molecular genetics 2022 Nov 28;31(23):3987-4005

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Ciclopirox drives growth arrest and autophagic cell death through STAT3 in gastric cancer cells.

Chen L, Chen D, Li J, He L, Chen T, Song D, Shan S, Wang J, Lu X, Lu B
Cell death & disease 2022 Nov 28;13(11):1007

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Targeting APLN/APJ restores blood-testis barrier and improves spermatogenesis in murine and human diabetic models.

Song K, Yang X, An G, Xia X, Zhao J, Xu X, Wan C, Liu T, Zheng Y, Ren S, Wang M, Chang G, Cronin SJF, Penninger JM, Jing T, Ou X, Rao S, Liu Z, Zhao XY
Nature communications 2022 Nov 28;13(1):7335

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Secreted EMC10 is upregulated in human obesity and its neutralizing antibody prevents diet-induced obesity in mice.

Wang X, Li Y, Qiang G, Wang K, Dai J, McCann M, Munoz MD, Gil V, Yu Y, Li S, Yang Z, Xu S, Cordoba-Chacon J, De Jesus DF, Sun B, Chen K, Wang Y, Liu X, Miao Q, Zhou L, Hu R, Ding Q, Kulkarni RN, Gao D, Blüher M, Liew CW
Nature communications 2022 Nov 28;13(1):7323

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Monochromatic Light Pollution Exacerbates High-Fat Diet-Induced Adipocytic Hypertrophy in Mice.

Guan Q, Li Y, Wang Z, Cao J, Dong Y, Ren F, Chen Y
Cells 2022 Nov 28;11(23)

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Resident intruder paradigm-induced PMDD rat model of premenstrual irritability: behavioral phenotypes, drug intervention, and biomarkers.

Gao M, Zhang H, Gao Z, Sun Y, Xu G, Wei F, Wang J, Gao D
Aging 2022 Nov 27;14(22):9210-9220

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Shikonin as a WT1 Inhibitor Promotes Promyeloid Leukemia Cell Differentiation.

Guo Z, Sun L, Xia H, Tian S, Liu M, Hou J, Li J, Lin H, Du G
Molecules (Basel, Switzerland) 2022 Nov 26;27(23)

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The Clostridium Metabolite P-Cresol Sulfate Relieves Inflammation of Primary Biliary Cholangitis by Regulating Kupffer Cells.

Fu HY, Xu JM, Ai X, Dang FT, Tan X, Yu HY, Feng J, Yang WX, Ma HT, Tu RF, Gupta AK, Manandhar LK, Bao WM, Tang YM
Cells 2022 Nov 26;11(23)

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USP14 regulates cell cycle progression through deubiquitinating CDK1 in breast cancer.

Liu Y, Xu J, Wang Y, Gan M, Hu Q, Wang J, Han T
Acta biochimica et biophysica Sinica 2022 Nov 25;54(11):1610-1618

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Exploring the Effective Components and Mechanism of Action of Japanese Ardisia in the Treatment of Autoimmune Hepatitis Based on Network Pharmacology and Experimental Verification.

Fu T, Chen Y, Li J, Zhu P, He H, Zhang W, Yung KKL, Wu W
Pharmaceuticals (Basel, Switzerland) 2022 Nov 24;15(12)

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hnRNP K Degrades Viral Nucleocapsid Protein and Induces Type I IFN Production to Inhibit Porcine Epidemic Diarrhea Virus Replication.

Qin W, Kong N, Wang C, Dong S, Zhai H, Zhai X, Yang X, Ye C, Ye M, Tong W, Liu C, Yu L, Zheng H, Yu H, Lan D, Zhang W, Tong G, Shan T
Journal of virology 2022 Nov 23;96(22):e0155522

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Orally Administered Ginkgolide C Attenuates DSS-Induced Colitis by Maintaining Gut Barrier Integrity, Inhibiting Inflammatory Responses, and Regulating Intestinal Flora.

Xu D, Zhuang L, Gao S, Ma H, Cheng J, Liu J, Liu D, Fu S, Hu G
Journal of agricultural and food chemistry 2022 Nov 23;70(46):14718-14731

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Branched-chain amino acid catabolism breaks glutamine addiction to sustain hepatocellular carcinoma progression.

Yang D, Liu H, Cai Y, Lu K, Zhong X, Xing S, Song W, Zhang Y, Ye L, Zhu X, Wang T, Zhang P, Li ST, Feng J, Jia W, Zhang H, Gao P
Cell reports 2022 Nov 22;41(8):111691

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Adenosine deaminase acting on RNA-1 is essential for early B lymphopoiesis.

Chen W, Li Y, Ruan GX, Huang H, Zhang R, Wang J, Ouyang Y, Li Y, Xu S, Ou X
Cell reports 2022 Nov 22;41(8):111687

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Effective-component compatibility of Bufei Yishen formula III ameliorated COPD by improving airway epithelial cell senescence by promoting mitophagy via the NRF2/PINK1 pathway.

Li MY, Qin YQ, Tian YG, Li KC, Oliver BG, Liu XF, Zhao P, Li JS
BMC pulmonary medicine 2022 Nov 22;22(1):434

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Functionally integrating nanoparticles alleviate deep vein thrombosis in pregnancy and rescue intrauterine growth restriction.

Cheng J, Zhang S, Li C, Li K, Jia X, Wei Q, Qi H, Zhang J
Nature communications 2022 Nov 22;13(1):7166

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IL-37 alleviates Coxsackievirus B3-induced viral myocarditis via inhibiting NLRP3 inflammasome-mediated pyroptosis.

Sun L, Yuan H, Zhao G
Scientific reports 2022 Nov 22;12(1):20077

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Dihydromyricetin Attenuates Depressive-like Behaviors in Mice by Inhibiting the AGE-RAGE Signaling Pathway.

Huang J, Chen B, Wang H, Hu S, Yu X, Reilly J, He Z, You Y, Shu X
Cells 2022 Nov 22;11(23)

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Essential role of MESP1-RING1A complex in cardiac differentiation.

Liang Q, Wang S, Zhou X, Li Y, Xing S, Sha Y, Yang F, Huang W, Liu N, Li Z, Chen Y, Xu Y, Zhu P, Lan F, Sun N
Developmental cell 2022 Nov 21;57(22):2533-2549.e7

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Characterization of Mitochondrial Alterations in Aicardi-Goutières Patients Mutated in RNASEH2A and RNASEH2B Genes.

Dragoni F, Garau J, Sproviero D, Orcesi S, Varesio C, De Siervi S, Gagliardi S, Cereda C, Pansarasa O
International journal of molecular sciences 2022 Nov 21;23(22)

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Apigenin Ameliorates Hyperuricemia and Renal Injury through Regulation of Uric Acid Metabolism and JAK2/STAT3 Signaling Pathway.

Liu T, Gao H, Zhang Y, Wang S, Lu M, Dai X, Liu Y, Shi H, Xu T, Yin J, Gao S, Wang L, Zhang D
Pharmaceuticals (Basel, Switzerland) 2022 Nov 21;15(11)

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BP5 alleviates endotoxemia-induced acute lung injury by activating Nrf2 via dual regulation of the Keap1-Nrf2 interaction and the Akt (Ser473)/GSK3β (Ser9)/Fyn pathway.

Li T, Geng Z, Zhang J, Xu L, Zhu X
Free radical biology & medicine 2022 Nov 20;193(Pt 1):304-318

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CRISPR-mediated MECOM depletion retards tumor growth by reducing cancer stem cell properties in lung squamous cell carcinoma.

Ma Y, Kang B, Li S, Xie G, Bi J, Li F, An G, Liu B, Li J, Shen Y, Xu X, Yang H, Yang Y, Gu Y, Wu N
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Nov 2;30(11):3341-3357

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Cyanidin Chloride Improves LPS-Induced Depression-Like Behavior in Mice by Ameliorating Hippocampal Inflammation and Excitotoxicity.

Qu D, Ye Z, Zhang W, Dai B, Chen G, Wang L, Shao X, Xiang A, Lu Z, Shi J
ACS chemical neuroscience 2022 Nov 2;13(21):3023-3033

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Girdin Promotes Tumorigenesis and Chemoresistance in Lung Adenocarcinoma by Interacting with PKM2.

Cao F, Yang D, Tang F, Lu C, He X, Chen S, Yang Z, Gong S, Sun L, Enomoto A, Takahashi M, Weng L
Cancers 2022 Nov 19;14(22)

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HBO1 catalyzes lysine benzoylation in mammalian cells.

Tan D, Wei W, Han Z, Ren X, Yan C, Qi S, Song X, Zheng YG, Wong J, Huang H
iScience 2022 Nov 18;25(11):105443

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In vitro evaluation of platelet extracellular vesicles (PEVs) for corneal endothelial regeneration.

Widyaningrum R, Wu YW, Delila L, Lee DY, Wang TJ, Burnouf T
Platelets 2022 Nov 17;33(8):1237-1250

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Circular RNA circPTPRF promotes the progression of GBM via sponging miR-1208 to up-regulate YY1.

Zhou J, Wang C, Liu Y, Cui D, Wang Z, Jiang Y, Gao L
Cancer cell international 2022 Nov 17;22(1):359

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Identification of purine biosynthesis as an NADH-sensing pathway to mediate energy stress.

Yang R, Yang C, Ma L, Zhao Y, Guo Z, Niu J, Chu Q, Ma Y, Li B
Nature communications 2022 Nov 17;13(1):7031

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Palmitic Acid Promotes Lung Metastasis of Melanomas via the TLR4/TRIF-Peli1-pNF-κB Pathway.

Zhang X, Li X, Xiong G, Yun F, Feng Y, Ni Q, Wu N, Yang L, Yi Z, Zhang Q, Yang Z, Kuang Y, Sai B, Zhu Y
Metabolites 2022 Nov 17;12(11)

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Bone marrow-targetable Green Tea Catechin-Based Micellar Nanocomplex for synergistic therapy of Acute myeloid leukemia.

Bae KH, Lai F, Mong J, Niibori-Nambu A, Chan KH, Her Z, Osato M, Tan MH, Chen Q, Kurisawa M
Journal of nanobiotechnology 2022 Nov 16;20(1):481

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LncRNA Airn alleviates diabetic cardiac fibrosis by inhibiting activation of cardiac fibroblasts via a m6A-IMP2-p53 axis.

Peng T, Liu M, Hu L, Guo D, Wang D, Qi B, Ren G, Hu C, Zhang F, Chun HJ, Song L, Hu J, Li Y
Biology direct 2022 Nov 16;17(1):32

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Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR cytosolic complex.

Gruszczyk J, Grandvuillemin L, Lai-Kee-Him J, Paloni M, Savva CG, Germain P, Grimaldi M, Boulahtouf A, Kwong HS, Bous J, Ancelin A, Bechara C, Barducci A, Balaguer P, Bourguet W
Nature communications 2022 Nov 16;13(1):7010

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Tea Tree Oil Mediates Antioxidant Factors Relish and Nrf2-Autophagy Axis Regulating the Lipid Metabolism of Macrobrachium rosenbergii.

Liu M, Zheng X, Sun C, Zhou Q, Liu B, Xu P
Antioxidants (Basel, Switzerland) 2022 Nov 16;11(11)

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Cadmium exposure induces pyroptosis in testicular tissue by increasing oxidative stress and activating the AIM2 inflammasome pathway.

Zhou J, Zeng L, Zhang Y, Wang M, Li Y, Jia Y, Wu L, Su P
The Science of the total environment 2022 Nov 15;847:157500

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Schisandra chinensis (Turcz.) Baill. Protects against DSS-induced colitis in mice: Involvement of TLR4/NF-κB/NLRP3 inflammasome pathway and gut microbiota.

Bian Z, Qin Y, Li L, Su L, Fei C, Li Y, Hu M, Chen X, Zhang W, Mao C, Yuan X, Lu T, Ji D
Journal of ethnopharmacology 2022 Nov 15;298:115570

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Anti-infective therapy using species-specific activators of Staphylococcus aureus ClpP.

Wei B, Zhang T, Wang P, Pan Y, Li J, Chen W, Zhang M, Ji Q, Wu W, Lan L, Gan J, Yang CG
Nature communications 2022 Nov 14;13(1):6909

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Promoting Effect of L-Fucose on the Regeneration of Intestinal Stem Cells through AHR/IL-22 Pathway of Intestinal Lamina Propria Monocytes.

Tan C, Hong G, Wang Z, Duan C, Hou L, Wu J, Qian W, Han C, Hou X
Nutrients 2022 Nov 12;14(22)

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Generative deep learning enables the discovery of a potent and selective RIPK1 inhibitor.

Li Y, Zhang L, Wang Y, Zou J, Yang R, Luo X, Wu C, Yang W, Tian C, Xu H, Wang F, Yang X, Li L, Yang S
Nature communications 2022 Nov 12;13(1):6891

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RAB27A promotes the proliferation and invasion of colorectal cancer cells.

Li Q, Zhao H, Dong W, Guan N, Hu Y, Zeng Z, Zhang H, Zhang F, Li Q, Yang J, Xiao W
Scientific reports 2022 Nov 12;12(1):19359

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Combination of tolvaptan and valsartan improves cardiac and renal functions in doxorubicin-induced heart failure in mice.

Yan F, Zhu H, He Y, Wu Q, Duan X
European journal of histochemistry : EJH 2022 Nov 11;66(4)

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Dihydrotanshinone I Inhibits the Proliferation and Growth of Oxaliplatin-Resistant Human HCT116 Colorectal Cancer Cells.

Wang M, Xiang Y, Wang R, Zhang L, Zhang H, Chen H, Luan X, Chen L
Molecules (Basel, Switzerland) 2022 Nov 11;27(22)

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DJ-1 Protein Inhibits Apoptosis in Cerebral Ischemia by Regulating the Notch1 and Nuclear Factor Erythroid2-Related Factor 2 Signaling Pathways.

Wang T, Xue Y, Li Y, Gao S, Peng L, Zhao Y, Yu S
Neuroscience 2022 Nov 10;504:33-46

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Phosphoproteomics revealed cellular signals immediately responding to disruption of cancer amino acid homeostasis induced by inhibition of L-type amino acid transporter 1.

Okanishi H, Ohgaki R, Xu M, Endou H, Kanai Y
Cancer & metabolism 2022 Nov 10;10(1):18

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KIF17 maintains the epithelial phenotype of breast cancer cells and curbs tumour metastasis.

Li T, Zhai D, Zhang M, Ye R, Kuang X, Shao N, Bi J, Lin Y
Cancer letters 2022 Nov 1;548:215904

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HA-ADT suppresses esophageal squamous cell carcinoma progression via apoptosis promotion and autophagy inhibition.

Duan SF, Zhang MM, Zhang X, Liu W, Zhang SH, Yang B, Dong Q, Han JG, Yu HL, Li T, Ji XY, Wu DD, Zhang XJ
Experimental cell research 2022 Nov 1;420(1):113341

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Mobilizing phospholipids on tumor plasma membrane implicates phosphatidylserine externalization blockade for cancer immunotherapy.

Wang W, Wu S, Cen Z, Zhang Y, Chen Y, Huang Y, Cillo AR, Prokopec JS, Quarato G, Vignali DAA, Stewart-Ornstein J, Li S, Lu B, Gong YN
Cell reports 2022 Nov 1;41(5):111582

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Effects of apolipoprotein E on regulating insulin sensitivity via regulating insulin receptor signalosome in caveolae.

Liu M, Chen MY, An L, Ma SQ, Mei J, Huang WH, Zhang W
Life sciences 2022 Nov 1;308:120929

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SIRT4 Expression Ameliorates the Detrimental Effect of Heat Stress via AMPK/mTOR Signaling Pathway in BMECs.

Ding Q, Wang Y, Xia SW, Zhao F, Zhong JF, Wang HL, Chen KL
International journal of molecular sciences 2022 Nov 1;23(21)

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Salidroside protects against osteoporosis in ovariectomized rats by inhibiting oxidative stress and promoting osteogenesis via Nrf2 activation.

Wang YF, Chang YY, Zhang XM, Gao MT, Zhang QL, Li X, Zhang L, Yao WF
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:154020

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Asperosaponin VI protects mice from sepsis by regulating Hippo and Rho signaling pathway.

Pang C, Wen C, Liang Y, Luo H, Wei L, Liu H, Qin T, Tan H, He C, Liu Y, Chen Y, Zeng S, Zhou C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:154010

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SiNiSan alleviates liver injury by promoting hepatic stem cell differentiation via Wnt/β-catenin signaling pathway.

Xu W, Du X, Li J, Zhang Z, Ma X, Luo D, Xiao M, Sun Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:153969

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MiR-1298-5p level downregulation induced by Helicobacter pylori infection inhibits autophagy and promotes gastric cancer development by targeting MAP2K6.

Li X, Zhu M, Zhao G, Zhou A, Min L, Liu S, Zhang N, Zhu S, Guo Q, Zhang S, Li P
Cellular signalling 2022 May;93:110286

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MYPT1/PP1-Mediated EZH2 Dephosphorylation at S21 Promotes Epithelial-Mesenchymal Transition in Fibrosis through Control of Multiple Families of Genes.

Zhang L, Wang L, Hu XB, Hou M, Xiao Y, Xiang JW, Xie J, Chen ZG, Yang TH, Nie Q, Fu JL, Wang Y, Zheng SY, Liu YF, Gan YW, Gao Q, Bai YY, Wang JM, Qi RL, Zou M, Ke Q, Zhu XF, Gong L, Liu Y, Li DW
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 May;9(14):e2105539

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Multistage targeting and dual inhibiting strategies based on bioengineered tumor matrix microenvironment-mediated protein nanocages for enhancing cancer biotherapy.

Hu F, Deng C, Zhou Y, Liu Y, Zhang T, Zhang P, Zhao Z, Miao H, Zheng W, Zhang W, Wang M, Ma X
Bioengineering & translational medicine 2022 May;7(2):e10290

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Macrophage-targeted delivery of siRNA to silence Mecp2 gene expression attenuates pulmonary fibrosis.

Mou Y, Wu GR, Wang Q, Pan T, Zhang L, Xu Y, Xiong W, Zhou Q, Wang Y
Bioengineering & translational medicine 2022 May;7(2):e10280

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Skimmianine as a novel therapeutic agent suppresses proliferation and migration of human esophageal squamous cell carcinoma via blocking the activation of ERK1/2.

Liu Y, Kang L, Shi SM, Li BJ, Zhang Y, Zhang XZ, Guo XW, Fu G, Zheng GN, Hao H, Zhao HF
Neoplasma 2022 May;69(3):571-582

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Intracellular hydroxyproline imprinting following resolution of bleomycin-induced pulmonary fibrosis.

Song S, Fu Z, Guan R, Zhao J, Yang P, Li Y, Yin H, Lai Y, Gong G, Zhao S, Yu J, Peng X, He Y, Luo Y, Zhong N, Su J
The European respiratory journal 2022 May;59(5)

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LncRNA LINC00152 promotes oral squamous cell carcinoma growth via enhancing Upstream Transcription Factor 1 mediated Mitochondrial Ribosomal Protein L52 transcription.

Zou X, Hu X, He F, Zhang M, Kong X, Rui S, Liu Y, Wang L, Zheng X, Liu J, Li Z, Luo H
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2022 May;51(5):454-463

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Absence of TNF Leads to Alternative Activation in Peritoneal Macrophages in Experimental Listeria Monocytogenes Infection.

Li X, Chen C, Zhang L, Cheng X, Geng H, Ji Q, Li C, Chen H, Körner H, Liu X
Immunological investigations 2022 May;51(4):1005-1022

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Neuregulin-1 regulates the conversion of M1/M2 microglia phenotype via ErbB4-dependent inhibition of the NF-κB pathway.

Ma Y, Fan P, Zhao R, Zhang Y, Wang X, Cui W
Molecular biology reports 2022 May;49(5):3975-3986

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27-hydroxycholesterol linked high cholesterol diet to lung adenocarcinoma metastasis.

Li X, Chen H, Zhang L, Chen L, Wei W, Gao S, Xue Q, Li Y, Wang B, Li J, Gao Y, Lin Y
Oncogene 2022 May;41(19):2685-2695

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Non-oxidative pentose phosphate pathway controls regulatory T cell function by integrating metabolism and epigenetics.

Liu Q, Zhu F, Liu X, Lu Y, Yao K, Tian N, Tong L, Figge DA, Wang X, Han Y, Li Y, Zhu Y, Hu L, Ji Y, Xu N, Li D, Gu X, Liang R, Gan G, Wu L, Zhang P, Xu T, Hu H, Hu Z, Xu H, Ye D, Yang H, Li B, Tong X
Nature metabolism 2022 May;4(5):559-574

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Serpina3c deficiency induced necroptosis promotes non-alcoholic fatty liver disease through β-catenin/Foxo1/TLR4 signaling.

Qian LL, Ji JJ, Jiang Y, Guo JQ, Wu Y, Yang Z, Ma GS, Yao YY
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 May;36(5):e22316

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Leonurine inhibits the TXNIP/NLRP3 and NF-κB pathways via Nrf2 activation to alleviate carrageenan-induced pleurisy in mice.

Yan K, Hu J, Hou T, Ci X, Peng L
Phytotherapy research : PTR 2022 May;36(5):2161-2172

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iTRAQ-derived quantitative proteomics uncovers the neuroprotective property of bexarotene in a mice model of cerebral ischemia-reperfusion injury.

Liu H, Wang H, Chen S, Liu S, Tian X, Dong Z, Xu L
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society 2022 May;30(5):585-594

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Schizosaccharomyces pombe Fzo1 is subjected to the ubiquitin-proteasome-mediated degradation during the stationary phase.

Ahmad F, Zhang Y, Yin H, Luo Y, Huang Y
International microbiology : the official journal of the Spanish Society for Microbiology 2022 May;25(2):397-404

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Cannabidiol inhibits methamphetamine-induced dopamine release via modulation of the DRD1-MeCP2-BDNF-TrkB signaling pathway.

Shen B, Zhang D, Zeng X, Guan L, Yang G, Liu L, Huang J, Li Y, Hong S, Li L
Psychopharmacology 2022 May;239(5):1521-1537

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Saccharides from Arctium lappa L. root reduce platelet activation and thrombus formation in a laser injury thrombosis mouse model.

Ruan Y, Ding Y, Li X, Zhang C, Wang M, Liu M, Wang L, Xing J, Hu L, Zhao X, Ding Z, Dong J, Liu Y
Experimental and therapeutic medicine 2022 May;23(5):344

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2-Deoxy-D-glucose increases the sensitivity of glioblastoma cells to BCNU through the regulation of glycolysis, ROS and ERS pathways: In vitro and in vivo validation.

Sun X, Fan T, Sun G, Zhou Y, Huang Y, Zhang N, Zhao L, Zhong R, Peng Y
Biochemical pharmacology 2022 May;199:115029

---

Urea transporter B downregulates polyamines levels in melanoma B16 cells via p53 activation.

Li J, Sun Y, Yan R, Wu X, Zou H, Meng Y
Biochimica et biophysica acta. Molecular cell research 2022 May;1869(5):119236

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A53T α-synuclein induces neurogenesis impairment and cognitive dysfunction in line M83 transgenic mice and reduces the proliferation of embryonic neural stem cells.

Zhang Y, Wu Q, Ren Y, Zhang Y, Feng L
Brain research bulletin 2022 May;182:118-129

---

Pseudorabies virus tegument protein UL13 recruits RNF5 to inhibit STING-mediated antiviral immunity.

Kong Z, Yin H, Wang F, Liu Z, Luan X, Sun L, Liu W, Shang Y
PLoS pathogens 2022 May;18(5):e1010544

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MEF2D-NR4A1-FAM134B2-mediated reticulophagy contributes to amino acid homeostasis.

Shiozaki Y, Miyazaki-Anzai S, Keenan AL, Miyazaki M
Autophagy 2022 May;18(5):1049-1061

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M1-type microglia can induce astrocytes to deposit chondroitin sulfate proteoglycan after spinal cord injury.

Yu SS, Li ZY, Xu XZ, Yao F, Luo Y, Liu YC, Cheng L, Zheng MG, Jing JH
Neural regeneration research 2022 May;17(5):1072-1079

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Recombinant P40 protein of Schistosoma japonicum inhibits TREM-1 expression in RAW264.7 cells via FOXO3a.

Shen P, Zhang T, Chen G, Zhang B, Huang A, Duan L, Zhu D, Chen J, Wang J, Duan Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 May;149:112826

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Remote cyclic compression ameliorates myocardial infarction injury in rats via AMPK-dependent pathway.

Xu S, Xia X, Liu Y, Chen F, Gu R, Bian X, Xu X, Jia C, Lu S, Gu Y, Bai H, Zhang H
Microvascular research 2022 May;141:104313

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Transformer 2 alpha homolog is a downstream gene of hypoxia-inducible factor 1 subunit alpha and is involved in the progression of pancreatic cancer.

Cao W, Lei S, Zeng Z, Xiao C, Sun B, Xie P, Li Y, Luo D, Yu W
Bioengineered 2022 May;13(5):13238-13251

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Dihydroartemisinin alleviates steatosis and inflammation in nonalcoholic steatohepatitis by decreasing endoplasmic reticulum stress and oxidative stress.

Li T, Chen Y, Tan P, Shi H, Huang Z, Cai T, Cheng Y, Du Y, Fu W
Bioorganic chemistry 2022 May;122:105737

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GM1 ganglioside modifies microglial and neuroinflammatory responses to α-synuclein in the rat AAV-A53T α-synuclein model of Parkinson's disease.

Schneider JS, Singh G, Williams CK, Singh V
Molecular and cellular neurosciences 2022 May;120:103729

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Targeting DCLK1 overcomes 5-fluorouracil resistance in colorectal cancer through inhibiting CCAR1/β-catenin pathway-mediated cancer stemness.

Wang L, Zhao L, Lin Z, Yu D, Jin M, Zhou P, Ren J, Cheng J, Yang K, Wu G, Zhang T, Zhang D
Clinical and translational medicine 2022 May;12(5):e743

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Ckip-1 Mediates P. gingivalis-Suppressed Cementoblast Mineralization.

Huang X, Ma L, Wang X, Wang H, Peng Y, Gao X, Huang H, Chen Y, Zhang Y, Cao Z
Journal of dental research 2022 May;101(5):599-608

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Identification of oleoylethanolamide as an endogenous ligand for HIF-3α.

Diao X, Ye F, Zhang M, Ren X, Tian X, Lu J, Sun X, Hou Z, Chen X, Li F, Zhuang J, Ding H, Peng C, Rastinejad F, Luo C, Wu D
Nature communications 2022 May 9;13(1):2529

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Forkhead Box q1 promotes invasion and metastasis in colorectal cancer by activating the epidermal growth factor receptor pathway.

Zhang JJ, Cao CX, Wan LL, Zhang W, Liu ZJ, Wang JL, Guo Q, Tang H
World journal of gastroenterology 2022 May 7;28(17):1781-1797

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Mitochondrial apolipoprotein A-I binding protein alleviates atherosclerosis by regulating mitophagy and macrophage polarization.

Duan M, Chen H, Yin L, Zhu X, Novák P, Lv Y, Zhao G, Yin K
Cell communication and signaling : CCS 2022 May 7;20(1):60

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BIN1 is a key regulator of proinflammatory and neurodegeneration-related activation in microglia.

Sudwarts A, Ramesha S, Gao T, Ponnusamy M, Wang S, Hansen M, Kozlova A, Bitarafan S, Kumar P, Beaulieu-Abdelahad D, Zhang X, Collier L, Szekeres C, Wood LB, Duan J, Thinakaran G, Rangaraju S
Molecular neurodegeneration 2022 May 7;17(1):33

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Small Extracellular Vesicles Containing miR-34c Derived from Bone Marrow Mesenchymal Stem Cells Regulates Epithelial Sodium Channel via Targeting MARCKS.

Hua Y, Han A, Yu T, Hou Y, Ding Y, Nie H
International journal of molecular sciences 2022 May 6;23(9)

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Combination of berberine and low glucose inhibits gastric cancer through the PP2A/GSK3β/MCL-1 signaling pathway.

Peng Z, Wangmu T, Li L, Han G, Huang D, Yi P
European journal of pharmacology 2022 May 5;922:174918

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CCDC50 suppresses NLRP3 inflammasome activity by mediating autophagic degradation of NLRP3.

Lin Y, Li Z, Wang Y, Tian T, Jia P, Ye Y, He M, Yang Z, Li C, Guo D, Hou P
EMBO reports 2022 May 4;23(5):e54453

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Targeted delivery of fat extract by platelet membrane-cloaked nanocarriers for the treatment of ischemic stroke.

Wang C, Yang X, Jiang Y, Qi L, Zhuge D, Xu T, Guo Y, Deng M, Zhang W, Tian D, Yin Q, Li L, Zhang Z, Wang Y, Yang GY, Chen Y, Tang Y
Journal of nanobiotechnology 2022 May 31;20(1):249

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Maternal Prenatal Inflammation Increases Brain Damage Susceptibility of Lipopolysaccharide in Adult Rat Offspring via COX-2/PGD-2/DPs Pathway Activation.

Zhang J, Yao P, Han W, Luo Y, Li Y, Yang Y, Xia H, Chen Z, Chen Q, Wang H, Yang L, Li H, Hu C, Huang H, Peng Z, Tan X, Li M, Yang J
International journal of molecular sciences 2022 May 30;23(11)

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SM22α-lineage niche cells regulate intramembranous bone regeneration via PDGFRβ-triggered hydrogen sulfide production.

Zhou X, Liu J, Zheng Y, Zhang Z, Wu Y, Yang W, Liu J, Huang Y, Yi Y, Zhao Z, Xiao H, Mo X, Wang J
Cell reports 2022 May 3;39(5):110750

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DNA methylation of miR-138 regulates cell proliferation and EMT in cervical cancer by targeting EZH2.

Chen R, Gan Q, Zhao S, Zhang D, Wang S, Yao L, Yuan M, Cheng J
BMC cancer 2022 May 3;22(1):488

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Therapeutic strategies targeting uPAR potentiate anti-PD-1 efficacy in diffuse-type gastric cancer.

Qin L, Wang L, Zhang J, Zhou H, Yang Z, Wang Y, Cai W, Wen F, Jiang X, Zhang T, Ye H, Long B, Qin J, Shi W, Guan X, Yu Z, Yang J, Wang Q, Jiao Z
Science advances 2022 May 27;8(21):eabn3774

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Novel dual-targeting c-Myc inhibitor D347-2761 represses myeloma growth via blocking c-Myc/Max heterodimerization and disturbing its stability.

Yao R, Zhang M, Zhou J, Liu L, Zhang Y, Gao J, Xu K
Cell communication and signaling : CCS 2022 May 26;20(1):73

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TARDBP Inhibits Porcine Epidemic Diarrhea Virus Replication through Degrading Viral Nucleocapsid Protein and Activating Type I Interferon Signaling.

Dong S, Kong N, Zhang Y, Li Y, Sun D, Qin W, Zhai H, Zhai X, Yang X, Ye C, Ye M, Liu C, Yu L, Zheng H, Tong W, Yu H, Zhang W, Tong G, Shan T
Journal of virology 2022 May 25;96(10):e0007022

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Aberrant methylmalonylation underlies methylmalonic acidemia and is attenuated by an engineered sirtuin.

Head PE, Myung S, Chen Y, Schneller JL, Wang C, Duncan N, Hoffman P, Chang D, Gebremariam A, Gucek M, Manoli I, Venditti CP
Science translational medicine 2022 May 25;14(646):eabn4772

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Role of Nrf2 Nucleus Translocation in Beauvericin-Induced Cell Damage in Rat Hepatocytes.

Shi J, Wang Y, Xu W, Cai G, Zou H, Yuan Y, Gu J, Liu Z, Bian J
Toxins 2022 May 25;14(6)

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Melatonin Alleviates Oxidative Stress Induced by H(2)O(2) in Porcine Trophectoderm Cells.

Fu Y, Chen Y, Jin Z, Gao H, Song G, Wang Q, Xu K
Antioxidants (Basel, Switzerland) 2022 May 25;11(6)

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Four AAs increase DMT1 abundance in duodenal brush-border membrane vesicles and enhance iron absorption in iron-deprived mice.

Woloshun RR, Yu Y, Xu X, Lee JK, Zhu S, Shine JS, Ebea P, Stevens BR, Vidyasagar S, Collins JF
Blood advances 2022 May 24;6(10):3011-3021

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Antibiotic pretreatment attenuates liver ischemia-reperfusion injury by Farnesoid X receptor activation.

Liu H, Wang J, Ding Y, Shi X, Ren H
Cell death & disease 2022 May 21;13(5):484

---

Premature translation termination mediated non-ER stress induced ATF6 activation by a ligand-dependent ribosomal frameshifting circuit.

Hsu HT, Murata A, Dohno C, Nakatani K, Chang K
Nucleic acids research 2022 May 20;50(9):5369-5383

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[P4HA2 promotes occurrence and progression of liver cancer by regulating the PI3K/Akt/mTOR signaling pathway].

Shang L, Jiang W, Zhang J, Wu W
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2022 May 20;42(5):665-672

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Overexpressed p-S6 associates with lymph node metastasis and predicts poor prognosis in non-small cell lung cancer.

Tang Y, Luo J, Zhou Y, Zang H, Yang Y, Liu S, Zheng H, Ma J, Fan S, Wen Q
BMC cancer 2022 May 20;22(1):564

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Inhibition of the CDK2 and Cyclin A complex leads to autophagic degradation of CDK2 in cancer cells.

Zhang J, Gan Y, Li H, Yin J, He X, Lin L, Xu S, Fang Z, Kim BW, Gao L, Ding L, Zhang E, Ma X, Li J, Li L, Xu Y, Horne D, Xu R, Yu H, Gu Y, Huang W
Nature communications 2022 May 20;13(1):2835

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Microarray Profiling and Co-Expression Network Analysis of LncRNAs and mRNAs in Acute Respiratory Distress Syndrome Mouse Model.

Wu X, Ma C, Ma Q, Zhuang P, Deng G
Pathogens (Basel, Switzerland) 2022 May 2;11(5)

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Cystathionine-β-synthase (CBS)/H2S system promotes lymph node metastasis of esophageal squamous cell carcinoma (ESCC) by activating SIRT1.

Liu Y, Pan L, Li Y, Deng Y, Han X, Fu H, Wang T
Carcinogenesis 2022 May 19;43(4):382-392

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Antisense oligonucleotides targeting the SMN2 promoter region enhance SMN2 expression in spinal muscular atrophy cell lines and mouse model.

Wang J, Bai J, OuYang S, Wang H, Jin Y, Peng X, Ge X, Jiao H, Zou J, He C, Xiao P, Song F, Qu Y
Human molecular genetics 2022 May 19;31(10):1635-1650

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Downregulation of lncRNA Miat contributes to the protective effect of electroacupuncture against myocardial fibrosis.

Qi W, Li X, Ren Y, Liu X, Fu H, Wang X, Li X, Xiong J, Zheng Q, Cai D, Liang F
Chinese medicine 2022 May 17;17(1):57

---

BMP4 Exerts Anti-Neurogenic Effect via Inducing Id3 during Aging.

Li T, Liu H, Jiang D, Yang K, Shen J, Feng H, Wang S, Zhang Y, Wang Y, Tang TS
Biomedicines 2022 May 17;10(5)

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TMCO1 expression promotes cell proliferation and induces epithelial-mesenchymal transformation in human gliomas.

Gao L, Ye Z, Liu JH, Yang JA, Li Y, Cai JY, Wang YX, Tong SA, Deng G, Zhang S, Chen QX
Medical oncology (Northwood, London, England) 2022 May 15;39(5):90

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Induction of p27 contributes to inhibitory effect of isorhapontigenin (ISO) on malignant transformation of human urothelial cells.

Huang M, Hua X, Xu J, Tian Z, Wang J, Chen H, Wang X, Shu P, Ye H, Shu J, Huang C
Cell cycle (Georgetown, Tex.) 2022 May 15;:1-14

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Induction of COX-2 by feline calicivirus via activation of the MEK1-ERK1/2 pathway, and attenuation of feline lung inflammation and injury by MEK1 inhibitor AZD6244 (selumetinib).

Liu Y, Shi WD, Xie QQ, Wang JG, Gu CC, Ji ZH, Xiao J, Liu WQ
Biochemical and biophysical research communications 2022 May 14;604:8-13

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Infectious Bronchitis Virus Nsp14 Degrades JAK1 to Inhibit the JAK-STAT Signaling Pathway in HD11 Cells.

Ma P, Gu K, Li H, Zhao Y, Li C, Wen R, Zhou C, Lei C, Yang X, Wang H
Viruses 2022 May 14;14(5)

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Hsa_circ_0000345 inhibits cell proliferation, migration and invasion of nasopharyngeal carcinoma cells via miR-513a-3p/PTEN axis.

Jiang C, Li H, Liu F, Shi L, Liu J, Li Y
The journal of physiological sciences : JPS 2022 May 12;72(1):10

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Human epididymis protein 4 aggravates airway inflammation and remodeling in chronic obstructive pulmonary disease.

Zhan Y, Chen J, Wu J, Gu Y, Huang Q, Deng Z, Chen S, Wu X, Lv Y, Zeng Z, Xie J
Respiratory research 2022 May 12;23(1):120

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Pu-erh Tea Restored Circadian Rhythm Disruption by Regulating Tryptophan Metabolism.

Hu S, Luo L, Bian X, Liu RH, Zhao S, Chen Y, Sun K, Jiang J, Liu Z, Zeng L
Journal of agricultural and food chemistry 2022 May 11;70(18):5610-5623

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Temporal Dynamics of the Ruminant Type I IFN-Induced Antiviral State against Homologous Parainfluenza Virus 3 Challenge In Vitro.

Sun M, Hao F, Li W, Cheng Z, Zhang W, Yang L, Mao L, Liu M
Viruses 2022 May 11;14(5)

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TGR5 Agonist INT-777 Alleviates Inflammatory Neurodegeneration in Parkinson's Disease Mouse Model by Modulating Mitochondrial Dynamics in Microglia.

Huang R, Gao Y, Chen J, Duan Q, He P, Zhang J, Huang H, Zhang Q, Ma G, Zhang Y, Nie K, Wang L
Neuroscience 2022 May 10;490:100-119

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Effect of 1-Deoxynojirimycin on insulin resistance in prediabetic mice based on next-generation sequencing and intestinal microbiota study.

Ren X, Xing Y, He L, Xiu Z, Yang L, Han A, Jia Q, Dong Y
Journal of ethnopharmacology 2022 May 10;289:115029

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P-Coumaric Acid Reverses Depression-Like Behavior and Memory Deficit Via Inhibiting AGE-RAGE-Mediated Neuroinflammation.

Yu XD, Zhang D, Xiao CL, Zhou Y, Li X, Wang L, He Z, Reilly J, Xiao ZY, Shu X
Cells 2022 May 10;11(10)

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Hepatokine ERAP1 Disturbs Skeletal Muscle Insulin Sensitivity Via Inhibiting USP33-Mediated ADRB2 Deubiquitination.

Niu Y, Jiang H, Yin H, Wang F, Hu R, Hu X, Peng B, Shu Y, Li Z, Chen S, Guo F
Diabetes 2022 May 1;71(5):921-933

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Design, synthesis and activity study of a novel PI3K degradation by hijacking VHL E3 ubiquitin ligase.

Wang H, Li C, Liu X, Ma M
Bioorganic & medicinal chemistry 2022 May 1;61:116707

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Curcumin protects against manganese-induced neurotoxicity in rat by regulating oxidative stress-related gene expression via H3K27 acetylation.

Yang Y, Liu Y, Zhang AL, Tang SF, Ming Q, Ao CY, Liu Y, Li CZ, Yu C, Zhao H, Chen L, Li J
Ecotoxicology and environmental safety 2022 May 1;236:113469

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Fabrication of SA/Gel/C scaffold with 3D bioprinting to generate micro-nano porosity structure for skin wound healing: a detailed animal in vivo study.

Niu C, Wang L, Ji D, Ren M, Ke D, Fu Q, Zhang K, Yang X
Cell regeneration (London, England) 2022 May 1;11(1):10

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Injectable self-healing hydrogel with siRNA delivery property for sustained STING silencing and enhanced therapy of intervertebral disc degeneration.

Chen J, Zhu H, Zhu Y, Zhao C, Wang S, Zheng Y, Xie Z, Jin Y, Song H, Yang L, Zhang J, Dai J, Hu Z, Wang H
Bioactive materials 2022 Mar;9:29-43

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Role of Lysocardiolipin Acyltransferase in Cigarette Smoke-Induced Lung Epithelial Cell Mitochondrial ROS, Mitochondrial Dynamics, and Apoptosis.

Bandela M, Suryadevara V, Fu P, Reddy SP, Bikkavilli K, Huang LS, Dhavamani S, Subbaiah PV, Singla S, Dudek SM, Ware LB, Ramchandran R, Natarajan V
Cell biochemistry and biophysics 2022 Mar;80(1):203-216

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Circular RNA PVT1 inhibits tendon stem/progenitor cell senescence by sponging microRNA-199a-5p.

Han W, Tao X, Weng T, Chen L
Toxicology in vitro : an international journal published in association with BIBRA 2022 Mar;79:105297

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Dysregulated lipid metabolism blunts the sensitivity of cancer cells to EZH2 inhibitor.

Zhang T, Guo Z, Huo X, Gong Y, Li C, Huang J, Wang Y, Feng H, Ma X, Jiang C, Yin Q, Xue L
EBioMedicine 2022 Mar;77:103872

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Long Non-coding Antisense RNA DDIT4-AS1 Regulates Meningitic Escherichia coli-Induced Neuroinflammation by Promoting DDIT4 mRNA Stability.

Yang B, Xu B, Yang R, Fu J, Li L, Huo D, Chen J, Yang X, Tan C, Chen H, Wang X
Molecular neurobiology 2022 Mar;59(3):1351-1365

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XBP1s promotes the development of lung adenocarcinoma via the p‑JNK MAPK pathway.

Jiang H, Jiang Q, He Y, Li X, Xu Y, Liu X
International journal of molecular medicine 2022 Mar;49(3)

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Epac activation ameliorates tubulointerstitial inflammation in diabetic nephropathy.

Yang WX, Liu Y, Zhang SM, Wang HF, Liu YF, Liu JL, Li XH, Zeng MR, Han YZ, Liu FY, Sun L, Xiao L
Acta pharmacologica Sinica 2022 Mar;43(3):659-671

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YTHDF2 promotes multiple myeloma cell proliferation via STAT5A/MAP2K2/p-ERK axis.

Hua Z, Wei R, Guo M, Lin Z, Yu X, Li X, Gu C, Yang Y
Oncogene 2022 Mar;41(10):1482-1491

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Nicotinamide N-methyltransferase ameliorates renal fibrosis by its metabolite 1-methylnicotinamide inhibiting the TGF-β1/Smad3 pathway.

Zhang W, Rong G, Gu J, Fan C, Guo T, Jiang T, Deng W, Xie J, Su Z, Yu Q, Mai J, Zheng R, Chen X, Tang X, Zhang J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Mar;36(3):e22084

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Ornithine decarboxylase of the fungal pathogen Colletotrichum higginsianum plays an important role in regulating global metabolic pathways and virulence.

Yan Y, Tang J, Yuan Q, Liu H, Huang J, Hsiang T, Bao C, Zheng L
Environmental microbiology 2022 Mar;24(3):1093-1116

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Proteomic analysis reveals that Xbp1s promotes hypoxic pulmonary hypertension through the p-JNK MAPK pathway.

Jiang H, Niu Y, He Y, Li X, Xu Y, Liu X
Journal of cellular physiology 2022 Mar;237(3):1948-1963

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Role of SLC39A6 in the development and progression of liver cancer.

Wan Z, Wang X
Oncology letters 2022 Mar;23(3):77

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Cordycepin prevents and ameliorates experimental autoimmune encephalomyelitis by inhibiting leukocyte infiltration and reducing neuroinflammation.

Song YC, Liu CT, Lee HJ, Yen HR
Biochemical pharmacology 2022 Mar;197:114918

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Chk1 Inhibition Ameliorates Alzheimer's Disease Pathogenesis and Cognitive Dysfunction Through CIP2A/PP2A Signaling.

Hu W, Wang Z, Zhang H, Mahaman YAR, Huang F, Meng D, Zhou Y, Wang S, Jiang N, Xiong J, Westermarck J, Lu Y, Wang J, Wang X, Shentu Y, Liu R
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2022 Mar;19(2):570-591

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LPS Activated Macrophages Induced Hepatocyte Pyroptosis via P2X7R Activation of NLRP3 in Mice.

Luo L, Fang Y, Yuan Q, Liao J, Zhang Z
Iranian journal of immunology : IJI 2022 Mar;19(1):4

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DECR1 directly activates HSL to promote lipolysis in cervical cancer cells.

Zhou H, Zhang J, Yan Z, Qu M, Zhang G, Han J, Wang F, Sun K, Wang L, Yang X
Biochimica et biophysica acta. Molecular and cell biology of lipids 2022 Mar;1867(3):159090

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C19orf12 ablation causes ferroptosis in mitochondrial membrane protein-associated with neurodegeneration.

Shao C, Zhu J, Ma X, Siedlak SL, Cohen ML, Lerner A, Wang W
Free radical biology & medicine 2022 Mar;182:23-33

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Maintaining homeostasis of mitochondria and endoplasmic reticulum with NSC228155 alleviates cisplatin-induced acute kidney injury.

Li Y, Jiang Y, Zhou W, Wu Y, Zhang S, Ding G, Zhang Y, Zhang A, Huang S, Jia Z, You R
Free radical biology & medicine 2022 Mar;181:270-287

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ROS-responsive nanoparticles for oral delivery of luteolin and targeted therapy of ulcerative colitis by regulating pathological microenvironment.

Tan C, Fan H, Ding J, Han C, Guan Y, Zhu F, Wu H, Liu Y, Zhang W, Hou X, Tan S, Tang Q
Materials today. Bio 2022 Mar;14:100246

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In situ injectable hydrogel-loaded drugs induce anti-tumor immune responses in melanoma immunochemotherapy.

Li J, Luo G, Zhang C, Long S, Guo L, Yang G, Wang F, Zhang L, Shi L, Fu Y, Zhang Y
Materials today. Bio 2022 Mar;14:100238

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MiR-7-5p suppresses invasion via downregulation of the autophagy-related gene ATG7 and increases chemoresistance to cisplatin in BCa.

Wang C, Tang Z, Zhang Z, Liu T, Zhang J, Huang H, Li Y
Bioengineered 2022 Mar;13(3):7328-7339

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Divergence of Tbx4 hindlimb enhancer HLEA underlies the hindlimb loss during cetacean evolution.

Liang N, Deme L, Kong Q, Sun L, Cao Y, Wu T, Huang X, Xu S, Yang G
Genomics 2022 Mar;114(2):110292

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Anti-PD-L1 antibody alleviates pulmonary fibrosis by inducing autophagy via inhibition of the PI3K/Akt/mTOR pathway.

Lu Y, Zhong W, Liu Y, Chen W, Zhang J, Zeng Z, Huang H, Qiao Y, Wan X, Meng X, Cai S, Dong H
International immunopharmacology 2022 Mar;104:108504

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Myricetin exerts its antiviral activity against infectious bronchitis virus by inhibiting the deubiquitinating activity of papain-like protease.

Peng S, Fang C, He H, Song X, Zhao X, Zou Y, Li L, Jia R, Yin Z
Poultry science 2022 Mar;101(3):101626

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Cinnamomi Ramulus inhibits the growth of colon cancer cells via Akt/ERK signaling pathways.

Pan B, Xia Y, Gao Z, Zhao G, Wang L, Fang S, Liu L, Yan S
Chinese medicine 2022 Mar 9;17(1):36

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Implications of miR-148a-3p/p35/PTEN signaling in tau hyperphosphorylation and autoregulatory feedforward of Akt/CREB in Alzheimer's disease.

Zeng L, Jiang H, Ashraf GM, Liu J, Wang L, Zhao K, Liu M, Li Z, Liu R
Molecular therapy. Nucleic acids 2022 Mar 8;27:256-275

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Highly efficient A-to-G base editing by ABE8.17 in rabbits.

Zhao D, Qian Y, Li J, Li Z, Lai L
Molecular therapy. Nucleic acids 2022 Mar 8;27:1156-1163

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LncRNA PVT1 promotes tumorigenesis of glioblastoma by recruiting COPS5 to deubiquitinate and stabilize TRIM24.

Lv T, Jin Y, Miao Y, Xu T, Jia F, Feng H, Zhang X
Molecular therapy. Nucleic acids 2022 Mar 8;27:109-121

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Hyperglycemia Promotes Endothelial Cell Senescence through AQR/PLAU Signaling Axis.

Wan Y, Liu Z, Wu A, Khan AH, Zhu Y, Ding S, Li X, Zhao Y, Dai X, Zhou J, Liu J, Li Y, Gong X, Liu M, Tian XL
International journal of molecular sciences 2022 Mar 7;23(5)

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RETRACTED: PINK1 deficiency in gastric cancer compromises mitophagy, promotes the Warburg effect, and facilitates M2 polarization of macrophages.

Xu Y, Lu J, Tang Y, Xie W, Zhang H, Wang B, Zhang S, Hou W, Zou C, Jiang P, Zhang W
Cancer letters 2022 Mar 31;529:19-36

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Regulation of chromatin accessibility by hypoxia and HIF.

Batie M, Frost J, Shakir D, Rocha S
The Biochemical journal 2022 Mar 31;479(6):767-786

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Skin epithelial cells change their mechanics and proliferation upon snail-mediated EMT signalling.

Hosseini K, Trus P, Frenzel A, Werner C, Fischer-Friedrich E
Soft matter 2022 Mar 30;18(13):2585-2596

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The SETD8/ELK1/bach1 complex regulates hyperglycaemia-mediated EndMT in diabetic nephropathy.

Li X, Lu L, Hou W, Wang F, Huang T, Meng Z, Zhu M
Journal of translational medicine 2022 Mar 29;20(1):147

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Construction of a Recombinant Japanese Encephalitis Virus with a Hemagglutinin-Tagged NS2A: A Model for an Analysis of Biological Characteristics and Functions of NS2A during Viral Infection.

Ma X, Li C, Xia Q, Zhang Y, Yang Y, Wahaab A, Liu K, Li Z, Li B, Qiu Y, Wei J, Ma Z
Viruses 2022 Mar 29;14(4)

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SETD8 cooperates with MZF1 to participate in hyperglycemia-induced endothelial inflammation via elevation of WNT5A levels in diabetic nephropathy.

Wang F, Hou W, Li X, Lu L, Huang T, Zhu M, Miao C
Cellular & molecular biology letters 2022 Mar 26;27(1):30

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TGF-β1-induced RAP2 regulates invasion in pancreatic cancer.

Jin K, Liu C, Cheng H, Fei Q, Huang Q, Xiao Z, Yu X, Wu W
Acta biochimica et biophysica Sinica 2022 Mar 25;54(3):361-369

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Highland barley Monascus purpureus Went extract ameliorates high-fat, high-fructose, high-cholesterol diet induced nonalcoholic fatty liver disease by regulating lipid metabolism in golden hamsters.

Zhao CZ, Jiang W, Zhu YY, Wang CZ, Zhong WH, Wu G, Chen J, Zhu MN, Wu QL, Du XL, Luo YY, Li M, Wang HL, Zhao H, Ma QG, Zhong GY, Wei RR
Journal of ethnopharmacology 2022 Mar 25;286:114922

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WWOX-Mediated Degradation of AMOTp130 Negatively Affects Egress of Filovirus VP40 Virus-Like Particles.

Liang J, Ruthel G, Freedman BD, Harty RN
Journal of virology 2022 Mar 23;96(6):e0202621

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Long noncoding RNA Gm31629 protects against mucosal damage in experimental colitis via YB-1/E2F pathway.

Feng X, Xiao Y, He J, Yang M, Guo Q, Su T, Huang Y, Yi J, Li CJ, Luo XH, Liu XW, Zhou HY
JCI insight 2022 Mar 22;7(6)

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NAD(+) Anabolism Disturbance Causes Glomerular Mesangial Cell Injury in Diabetic Nephropathy.

Li X, Li Y, Li F, Chen Q, Zhao Z, Liu X, Zhang N, Li H
International journal of molecular sciences 2022 Mar 22;23(7)

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Peroxidase-like Active Nanomedicine with Dual Glutathione Depletion Property to Restore Oxaliplatin Chemosensitivity and Promote Programmed Cell Death.

Wu F, Du Y, Yang J, Shao B, Mi Z, Yao Y, Cui Y, He F, Zhang Y, Yang P
ACS nano 2022 Mar 22;16(3):3647-3663

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Co-delivery of EGCG and lycopene via a pickering double emulsion induced synergistic hypolipidemic effect.

Wang Q, Wang L, Abdullah, Tian W, Song M, Cao Y, Xiao J
Food & function 2022 Mar 21;13(6):3419-3430

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Ascorbic acid 2-glucoside preconditioning enhances the ability of bone marrow mesenchymal stem cells in promoting wound healing.

Yi Y, Wu M, Zhou X, Xiong M, Tan Y, Yu H, Liu Z, Wu Y, Zhang Q
Stem cell research & therapy 2022 Mar 21;13(1):119

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Folic Acid-Modified Fluorescent-Magnetic Nanoparticles for Efficient Isolation and Identification of Circulating Tumor Cells in Ovarian Cancer.

Pan Y, Wang Z, Ma J, Zhou T, Wu Z, Ding P, Sun N, Liu L, Pei R, Zhu W
Biosensors 2022 Mar 21;12(3)

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lncRNA HITT inhibits metastasis by attenuating Rab5-mediated endocytosis in lung adenocarcinoma.

Wang X, Zheng S, Yang F, Zhang W, Zhao D, Xue X, Lin Q, He Y, Hu G, Hu Y
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Mar 2;30(3):1071-1088

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An advanced network pharmacology study to explore the novel molecular mechanism of Compound Kushen Injection for treating hepatocellular carcinoma by bioinformatics and experimental verification.

Lu S, Meng Z, Tan Y, Wu C, Huang Z, Huang J, Fu C, Stalin A, Guo S, Liu X, You L, Li X, Zhang J, Zhou W, Zhang X, Wang M, Wu J
BMC complementary medicine and therapies 2022 Mar 2;22(1):54

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MYCT1 alters the glycogen shunt by regulating selective translation of RACK1-mediated enzymes.

Ding DX, Wang Y, Yan W, Fu WN
iScience 2022 Mar 18;25(3):103955

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Structures of a deltacoronavirus spike protein bound to porcine and human receptors.

Ji W, Peng Q, Fang X, Li Z, Li Y, Xu C, Zhao S, Li J, Chen R, Mo G, Wei Z, Xu Y, Li B, Zhang S
Nature communications 2022 Mar 18;13(1):1467

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Cancer stem cell regulated phenotypic plasticity protects metastasized cancer cells from ferroptosis.

Wu M, Zhang X, Zhang W, Chiou YS, Qian W, Liu X, Zhang M, Yan H, Li S, Li T, Han X, Qian P, Liu S, Pan Y, Lobie PE, Zhu T
Nature communications 2022 Mar 16;13(1):1371

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Novel phosphanegold(I) thiolate complexes suppress de novo lipid synthesis in human lung cancer.

Luo M, Ma X, Jiang W, Zhang J, Liu W, Wei S, Liu H
European journal of medicinal chemistry 2022 Mar 15;232:114168

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Transition of autophagy and apoptosis in fibroblasts depends on dominant expression of HIF-1α or p53.

Li M, Su Y, Gao X, Yu J, Wang Z, Wang X
Journal of Zhejiang University. Science. B 2022 Mar 15;23(3):204-217

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ALKBH3-dependent m(1)A demethylation of Aurora A mRNA inhibits ciliogenesis.

Kuang W, Jin H, Yang F, Chen X, Liu J, Li T, Chang Y, Liu M, Xu Z, Huo C, Yan X, Yang Y, Liu W, Shu Q, Xie S, Zhou T
Cell discovery 2022 Mar 11;8(1):25

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Knockdown of long noncoding RNA MIAT attenuates cigarette smoke-induced airway remodeling by downregulating miR-29c-3p-HIF3A axis.

Gu W, Wang L, Deng G, Gu X, Tang Z, Li S, Jin W, Yang J, Guo X, Li Q
Toxicology letters 2022 Mar 1;357:11-19

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Zinc finger protein 91 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation.

Zhong Y, Zhang ZH, Wang JY, Xing Y, Ri MH, Jin HL, Zuo HX, Li MY, Ma J, Jin X
Toxicology letters 2022 Mar 1;356:75-88

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Systematic characterization of the metabolites of defatted walnut powder extract in vivo and screening of the mechanisms against NAFLD by UPLC-Q-Exactive Orbitrap MS combined with network pharmacology.

Ren SM, Zhang QZ, Jiang M, Chen ML, Xu XJ, Wang DM, Pan YN, Liu XQ
Journal of ethnopharmacology 2022 Mar 1;285:114870

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RKIP Induction Promotes Tumor Differentiation via SOX2 Degradation in NF2-Deficient Conditions.

Cho JH, Park S, Kim S, Kang SM, Woo TG, Yoon MH, Lee H, Jeong M, Park YH, Kim H, Han YT, Suh YG, Kim BH, Kwon Y, Yun H, Park BJ
Molecular cancer research : MCR 2022 Mar 1;20(3):412-424

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Tumor Necrosis Factor-α-Induced Protein 8-Like 2 Fosters Tumor-Associated Microbiota to Promote the Development of Colorectal Cancer.

Lou Y, Song M, Han M, Zhong J, Tian X, Ren Y, Song Y, Duan L, Zhao P, Song X, Zhang W, Chen YH, Wang H
Cancer immunology research 2022 Mar 1;10(3):354-367

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KLF2 mediates the suppressive effect of BDNF on diabetic intimal calcification by inhibiting HK1 induced endothelial-to-mesenchymal transition.

Wang FF, Zhang JL, Ji Y, Yan XJ, Sun L, Zhu Y, Jin H
Cellular signalling 2022 Jun;94:110324

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Synchronous Disintegration of Ferroptosis Defense Axis via Engineered Exosome-Conjugated Magnetic Nanoparticles for Glioblastoma Therapy.

Li B, Chen X, Qiu W, Zhao R, Duan J, Zhang S, Pan Z, Zhao S, Guo Q, Qi Y, Wang W, Deng L, Ni S, Sang Y, Xue H, Liu H, Li G
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jun;9(17):e2105451

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Acute Myeloid Leukemia Cells Educate Mesenchymal Stromal Cells toward an Adipogenic Differentiation Propensity with Leukemia Promotion Capabilities.

Zhang L, Zhao Q, Cang H, Wang Z, Hu X, Pan R, Yang Y, Chen Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jun;9(16):2105811

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Circ_0060731 mediated miR-21-5p-PDCD4/ESR1 pathway to induce apoptosis of placental trophoblasts in intrahepatic cholestasis of pregnancy.

Feng F, Lei L, Liao J, Huang X, Shao Y
Tissue & cell 2022 Jun;76:101771

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Palbociclib regulates intracellular lipids in mammary tumor cells by secreting lipoprotein lipase.

Fujii T, Kamishikiryo J, Morita T
Pharmacological reports : PR 2022 Jun;74(3):503-512

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Targeting RPL23 restores chemosensitivity of cisplatin-resistant ovarian carcinoma by inhibiting EMT.

Liu Y, Lai S, He J, Wan J, Fu F, Jinlong Y
Cytotechnology 2022 Jun;74(3):421-432

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Differential Expression of CB(1) Cannabinoid Receptor and Cannabinoid Receptor Interacting Protein 1a in Labor.

Kozakiewicz ML, Zhang J, Leone-Kabler S, Yamaleyeva LM, McDonald AG, Brost BC, Howlett AC
Cannabis and cannabinoid research 2022 Jun;7(3):279-288

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Maternal Prkce expression in mature oocytes is critical for the first cleavage facilitating maternal-to-zygotic transition in mouse early embryos.

Zhang S, Gong X, Zhou Y, Ma Q, Cai Q, Yang G, Guo X, Chen Y, Xu M, Zhu Y, Zeng Y, Zeng F
Cell proliferation 2022 Jun;55(6):e13231

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Bicyclol alleviates high-fat diet-induced hepatic ER stress- and autophagy-associated non-alcoholic fatty liver disease/non-alcoholic steatohepatitis in mice.

Jia S, Jin L, Cheng X, Wu J, Yao X, Shao J, Zhang C, Cen D, Cheng B, Wang J, Chen L, Yao X
Drug development and industrial pharmacy 2022 Jun;48(6):247-254

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Tetrandrine Ameliorates Traumatic Brain Injury by Regulating Autophagy to Reduce Ferroptosis.

Liu H, He S, Wang J, Li C, Liao Y, Zou Q, Chen R
Neurochemical research 2022 Jun;47(6):1574-1587

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The function and mechanism of dopamine in the activation of CD4(+) T cell.

Shao Y, Dong Y, Wang W, Chen Z, Hao C, Yang Y, Zhang J
Immunopharmacology and immunotoxicology 2022 Jun;44(3):410-420

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Osthole inhibits the migration and invasion of highly metastatic breast cancer cells by suppressing ITGα3/ITGβ5 signaling.

Chen YQ, Song HY, Zhou ZY, Ma J, Luo ZY, Zhou Y, Wang JY, Liu S, Han XH
Acta pharmacologica Sinica 2022 Jun;43(6):1544-1555

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LncRNA-6395 promotes myocardial ischemia-reperfusion injury in mice through increasing p53 pathway.

Zhan LF, Zhang Q, Zhao L, Dong X, Pei XY, Peng LL, Zhang XW, Meng B, Shang WD, Pan ZW, Xu CQ, Lu YJ, Zhang MY
Acta pharmacologica Sinica 2022 Jun;43(6):1383-1394

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Caffeine Citrate Protects Against Sepsis-Associated Encephalopathy and Inhibits the UCP2/NLRP3 Axis in Astrocytes.

Hu J, Cheng Y, Chen P, Huang Z, Yang L
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2022 Jun;42(6):267-278

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Melatonin Alleviates Liver Fibrosis by Inhibiting Autophagy.

Jie L, Hong RT, Zhang YJ, Sha LL, Chen W, Ren XF
Current medical science 2022 Jun;42(3):498-504

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ADH1C Facilitates Cisplatin Resistance of Lung Adenocarcinoma Cells.

Jiang F, Shen Q, Zhang F, Fu J, Hu L, Wang J, Zhou H, Chen J, Wang Y
DNA and cell biology 2022 Jun;41(6):631-640

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Protection of pancreatic β-cell by phosphocreatine through mitochondrial improvement via the regulation of dual AKT/IRS-1/GSK-3β and STAT3/Cyp-D signaling pathways.

Wang H, Ai J, Shopit A, Niu M, Ahmed N, Tesfaldet T, Tang Z, Li X, Jamalat Y, Chu P, Peng J, Ma X, Qaed E, Han G, Zhang W, Wang J, Tang Z
Cell biology and toxicology 2022 Jun;38(3):531-551

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HDM induce airway epithelial cell ferroptosis and promote inflammation by activating ferritinophagy in asthma.

Zeng Z, Huang H, Zhang J, Liu Y, Zhong W, Chen W, Lu Y, Qiao Y, Zhao H, Meng X, Zou F, Cai S, Dong H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jun;36(6):e22359

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Rutin-activated adipose tissue thermogenesis is correlated with increased intestinal short-chain fatty acid levels.

Cheng L, Shi L, He C, Wang C, Lv Y, Li H, An Y, Dai H, Duan Y, Zhang H, Huang Y, Fu W, Meng Y, Zhao B
Phytotherapy research : PTR 2022 Jun;36(6):2495-2510

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MiR-153 downregulation alleviates PTSD-like behaviors and reduces cell apoptosis by upregulating the Sigma-1 receptor in the hippocampus of rats exposed to single-prolonged stress.

Chen YL, Tong L, Chen Y, Fu CH, Peng JB, Ji LL
Experimental neurology 2022 Jun;352:114034

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Early environmental enrichment for autism spectrum disorder Fmr1 mice models has positive behavioral and molecular effects.

Chen YS, Zhang SM, Yue CX, Xiang P, Li JQ, Wei Z, Xu L, Zeng Y
Experimental neurology 2022 Jun;352:114033

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Overexpression of G Protein-Coupled Receptor 40 Protects Obesity-Induced Cardiomyopathy Through the SIRT1/LKB1/AMPK Pathway.

Li SN, Yu YL, Wang BY, Qiao SY, Hu MM, Wang H, Fu CN, Dong B
Human gene therapy 2022 Jun;33(11-12):598-613

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The anti-angiogenesis mechanism of Geniposide on rheumatoid arthritis is related to the regulation of PTEN.

Bu Y, Wu H, Deng R, Wang Y
Inflammopharmacology 2022 Jun;30(3):1047-1062

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Alternative splicing of the human rhomboid family-1 gene RHBDF1 inhibits epidermal growth factor receptor activation.

Ji R, Shi Q, Cao Y, Zhang J, Zhao C, Zhao H, Sayyed Y, Fu L, Li LY
The Journal of biological chemistry 2022 Jun;298(6):102033

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Mammalian PERIOD2 regulates H2A.Z incorporation in chromatin to orchestrate circadian negative feedback.

Tartour K, Andriani F, Folco EG, Letkova D, Schneider R, Saidi I, Sato T, Welz PS, Benitah SA, Allier C, Padmanabhan K
Nature structural & molecular biology 2022 Jun;29(6):549-562

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Lithium attenuates blood-brain barrier damage and brain edema following intracerebral hemorrhage via an endothelial Wnt/β-catenin signaling-dependent mechanism in mice.

Song D, Ji YB, Huang XW, Ma YZ, Fang C, Qiu LH, Tan XX, Chen YM, Wang SN, Chang J, Guo F
CNS neuroscience & therapeutics 2022 Jun;28(6):862-872

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Tanshinone IIA inhibits cell growth by suppressing SIX1-induced aerobic glycolysis in non-small cell lung cancer cells.

Qi H, Chen Z, Qin Y, Wang X, Zhang Z, Li Y
Oncology letters 2022 Jun;23(6):184

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Proteomic analysis reveals the heterogeneity of metabolic reprogramming in lacrimal gland tumors.

Yang J, Li Y, Gao W, Feng Y, He X, Ni H, Song X, Fan J
Experimental eye research 2022 Jun;219:109052

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MicroRNA-221-5p Promotes Ricin Toxin-induced Inflammation via PI3K/Akt signaling pathway by targeting COL4a5.

Zhao N, Yu H, Xi Y, Dong M, Wang Y, Sun C, Zhang J, Xu N, Liu W
Toxicon : official journal of the International Society on Toxinology 2022 Jun;212:11-18

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AMG487 inhibits PRRSV replication and ameliorates lung injury in pig lung xenografts by down-regulating the expression of ANXA2.

Liu J, Yao L, Huang S, Wang B, Li L, Li L, Gu W, Xiao S, Liu G
Antiviral research 2022 Jun;202:105314

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FAIM regulates autophagy through glutaminolysis in lung adenocarcinoma.

Han T, Wang P, Wang Y, Xun W, Lei J, Wang T, Lu Z, Gan M, Zhang W, Yu B, Wang JB
Autophagy 2022 Jun;18(6):1416-1432

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HGF Secreted by Mesenchymal Stromal Cells Promotes Primordial Follicle Activation by Increasing the Activity of the PI3K-AKT Signaling Pathway.

Mi X, Jiao W, Yang Y, Qin Y, Chen ZJ, Zhao S
Stem cell reviews and reports 2022 Jun;18(5):1834-1850

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Ephedra herb reduces adriamycin-induced testicular toxicity by upregulating the gonadotropin-releasing hormone signalling pathway.

Fu Y, Yuan P, Zheng Y, Gao L, Wei Y, Chen Y, Li P, Ruan Y, Zheng X, Feng W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:113061

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Naringin suppressed airway inflammation and ameliorated pulmonary endothelial hyperpermeability by upregulating Aquaporin1 in lipopolysaccharide/cigarette smoke-induced mice.

Zhang HH, Zhou XJ, Zhong YS, Ji LT, Yu WY, Fang J, Ying HZ, Li CY
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:113035

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Berberine reduces hepatic ceramide levels to improve insulin resistance in HFD-fed mice by inhibiting HIF-2α.

Xia QS, Wu F, Wu WB, Dong H, Huang ZY, Xu L, Lu FE, Gong J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:112955

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Abrogation of ARF6 in promoting erastin-induced ferroptosis and mitigating capecitabine resistance in gastric cancer cells.

Geng D, Wu H
Journal of gastrointestinal oncology 2022 Jun;13(3):958-967

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DR1 Activation Inhibits the Proliferation of Vascular Smooth Muscle Cells through Increasing Endogenous H(2)S in Diabetes.

Xi Y, Wen X, Zhang Y, Jiao L, Bai S, Shi S, Chang G, Wu R, Sun F, Hao J, Li H
Aging and disease 2022 Jun;13(3):910-926

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Effects of 2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione on autophagy and the PI3K/AKT/mTOR signaling pathway in human cholangiocarcinoma QBC939 cells.

He Y, Li Y, Liang T, Mo S, Liao Y, Chen Z, Zhao S, Ran Q, Han C, Hoa PTT
Journal of gastrointestinal oncology 2022 Jun;13(3):1423-1432

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SORTING NEXIN2 proteins mediate stomatal movement and the response to drought stress by modulating trafficking and protein levels of the ABA exporter ABCG25.

Liang C, Li C, Wu J, Zhao M, Chen D, Liu C, Chu J, Zhang W, Hwang I, Wang M
The Plant journal : for cell and molecular biology 2022 Jun;110(6):1603-1618

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Dietary curcumin supplementation ameliorates placental inflammation in rats with intra-uterine growth retardation by inhibiting the NF-κB signaling pathway.

Qi L, Jiang J, Yu G, Zhang X, Qi X, Zhang J, Zhang L, Wang T
The Journal of nutritional biochemistry 2022 Jun;104:108973

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Genome-scale CRISPR-Cas9 screen reveals novel regulators of B7-H3 in tumor cells.

Zhao S, Wang Y, Yang N, Mu M, Wu Z, Li H, Tang X, Zhong K, Zhang Z, Huang C, Cao T, Zheng M, Wang G, Nie C, Yang H, Guo G, Zhou L, Zheng X, Tong A
Journal for immunotherapy of cancer 2022 Jun;10(6)

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Small molecule targeting FOXM1 DNA binding domain exhibits anti-tumor activity in ovarian cancer.

Zhang Z, Xue ST, Gao Y, Li Y, Zhou Z, Wang J, Li Z, Liu Z
Cell death discovery 2022 Jun 9;8(1):280

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Novel Sphingosine Kinase 1 Inhibitor Suppresses Growth of Solid Tumor and Inhibits the Lung Metastasis of Triple-Negative Breast Cancer.

Zhang S, Chen X, Wu C, Xu H, Xie X, Feng M, Hu S, Bai H, Gao F, Tong L, Ding J, Liu H, Xie Z, Wang J
Journal of medicinal chemistry 2022 Jun 9;65(11):7697-7716

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Recombinant ACE2 protein protects against acute lung injury induced by SARS-CoV-2 spike RBD protein.

Zhang L, Zhang Y, Qin X, Jiang X, Zhang J, Mao L, Jiang Z, Jiang Y, Liu G, Qiu J, Chen C, Qiu F, Zou Z
Critical care (London, England) 2022 Jun 9;26(1):171

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Zebrafish Xenograft Model for Studying Pancreatic Cancer-Instructed Innate Immune Microenvironment.

Wang X, Li W, Jiang H, Ma C, Huang M, Wei X, Wang W, Jing L
International journal of molecular sciences 2022 Jun 9;23(12)

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Novel Thermosensitive Hydrogel Promotes Spinal Cord Repair by Regulating Mitochondrial Function.

Li Y, Yang L, Hu F, Xu J, Ye J, Liu S, Wang L, Zhuo M, Ran B, Zhang H, Ye J, Xiao J
ACS applied materials & interfaces 2022 Jun 8;14(22):25155-25172

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Structural basis of substrate recognition and translocation by human very long-chain fatty acid transporter ABCD1.

Chen ZP, Xu D, Wang L, Mao YX, Li Y, Cheng MT, Zhou CZ, Hou WT, Chen Y
Nature communications 2022 Jun 8;13(1):3299

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The circadian clock protein Rev-erbα provides neuroprotection and attenuates neuroinflammation against Parkinson's disease via the microglial NLRP3 inflammasome.

Kou L, Chi X, Sun Y, Han C, Wan F, Hu J, Yin S, Wu J, Li Y, Zhou Q, Zou W, Xiong N, Huang J, Xia Y, Wang T
Journal of neuroinflammation 2022 Jun 6;19(1):133

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Anti-tumor activity of polysaccharides extracted from Pinus massoniana pollen in colorectal cancer- in vitro and in vivo studies.

Shang H, Niu X, Cui W, Sha Z, Wang C, Huang T, Guo P, Wang X, Gao P, Zhang S, Wei K, Zhu R
Food & function 2022 Jun 6;13(11):6350-6361

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Overexpression of VPS16 correlates with tumor progression and chemoresistance in colorectal cancer.

Zhang B, Ma Y, Niu H, Liu Z
Biochemical and biophysical research communications 2022 Jun 4;607:81-88

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Carboxymethyl Chitosan Modified Oxymatrine Liposomes for the Alleviation of Emphysema in Mice via Pulmonary Administration.

Peng J, Cai Z, Wang Q, Zhou J, Xu J, Pan D, Chen T, Zhang G, Tao L, Chen Y, Shen X
Molecules (Basel, Switzerland) 2022 Jun 4;27(11)

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C. elegans monitor energy status via the AMPK pathway to trigger innate immune responses against bacterial pathogens.

Ju S, Chen H, Wang S, Lin J, Ma Y, Aroian RV, Peng D, Sun M
Communications biology 2022 Jun 30;5(1):643

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Extracellular Vesicles-Encapsulated miR-153-3p Potentiate the Survival and Invasion of Lung Adenocarcinoma.

Cao H, Zhang P, Yu H, Xi J
Molecules and cells 2022 Jun 30;45(6):376-387

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Targeting the SREBP-1/Hsa-Mir-497/SCAP/FASN Oncometabolic Axis Inhibits the Cancer Stem-like and Chemoresistant Phenotype of Non-Small Cell Lung Carcinoma Cells.

Tiong TY, Weng PW, Wang CH, Setiawan SA, Yadav VK, Pikatan NW, Fong IH, Yeh CT, Hsu CH, Kuo KT
International journal of molecular sciences 2022 Jun 30;23(13)

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Effects of butyphthalide on microglia polarization after intracerebral hemorrhage and the underlying mechanisms.

Zhang Y, Lu W, Xu N
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 2022 Jun 28;47(6):717-729

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The mechanism of dioscin preventing lung cancer based on network pharmacology and experimental validation.

Xi P, Niu Y, Zhang Y, Li W, Gao F, Gu W, Kui F, Liu Z, Lu L, Du G
Journal of ethnopharmacology 2022 Jun 28;292:115138

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All-trans retinoic acid increases the pathogenicity of the H9N2 influenza virus in mice.

Niu X, Wang H, Zhao L, Lian P, Bai Y, Li J, Qiao J
Virology journal 2022 Jun 28;19(1):113

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Oncostatin M receptor regulates osteoblast differentiation via extracellular signal-regulated kinase/autophagy signaling.

Zhou J, Yang J, Dong Y, Shi Y, Zhu E, Yuan H, Li X, Wang B
Stem cell research & therapy 2022 Jun 28;13(1):278

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Salubrinal-mediated activation of eIF2α signaling improves oxidative stress-induced BMSCs senescence and senile osteoporosis.

Li L, Hu G, Xie R, Yang J, Shi X, Jia Z, Qu X, Wang M, Wu Y
Biochemical and biophysical research communications 2022 Jun 25;610:70-76

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KDM6B promotes PARthanatos via suppression of O6-methylguanine DNA methyltransferase repair and sustained checkpoint response.

Yang M, Wang C, Zhou M, Bao L, Wang Y, Kumar A, Xing C, Luo W, Wang Y
Nucleic acids research 2022 Jun 24;50(11):6313-6331

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Bisacodyl Limits Chikungunya Virus Replication In Vitro and Is Broadly Antiviral.

LoMascolo NJ, Cruz-Pulido YE, Mounce BC
Antimicrobial agents and chemotherapy 2022 Jun 21;66(6):e0029222

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Ferroptosis participates in neuron damage in experimental cerebral malaria and is partially induced by activated CD8(+) T cells.

Liang J, Shen Y, Wang Y, Huang Y, Wang J, Zhu Q, Tong G, Yu K, Cao W, Wang Q, Li Y, Zhao Y
Molecular brain 2022 Jun 20;15(1):57

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Phloretin ameliorates diabetic nephropathy by inhibiting nephrin and podocin reduction through a non-hypoglycemic effect.

Liu J, Sun M, Xia Y, Cui X, Jiang J
Food & function 2022 Jun 20;13(12):6613-6622

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Baicalin alleviates endometrial inflammatory injury through regulation of tight junction proteins.

Yang D, Yin R, Lei Q, Zhu J, Nan S, Ma N, Zhu H, Chen J, Han L, Ding M, Ding Y
Food & function 2022 Jun 20;13(12):6522-6533

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Probiotic Bifidobacterium breve MCC1274 Mitigates Alzheimer's Disease-Related Pathologies in Wild-Type Mice.

Abdelhamid M, Zhou C, Jung CG, Michikawa M
Nutrients 2022 Jun 19;14(12)

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Enhanced autophagy promotes radiosensitivity by mediating Sirt1 downregulation in RM-1 prostate cancer cells.

Wang KX, Yan C, Yang X, Zhu PY, Cui WW, Ye C, Hu K, Lan T, Huang LY, Wang W, Ma P, Qi SH, Gu B, Luo L
Biochemical and biophysical research communications 2022 Jun 18;609:84-92

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Inhibition of noncaspase proteases, calpain and proteasome, via ALLN and Bortezomib contributes to cell death through low degradation of pro-/anti-apoptotic proteins and apoptosis induction.

Hamidi R, Ataei F, Hosseinkhani S
Medical oncology (Northwood, London, England) 2022 Jun 18;39(9):125

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Inhibition of AKT induces p53/SIRT6/PARP1-dependent parthanatos to suppress tumor growth.

Zhang Y, Zhang C, Li J, Jiang M, Guo S, Yang G, Zhang L, Wang F, Yi S, Wang J, Fu Y, Zhang Y
Cell communication and signaling : CCS 2022 Jun 17;20(1):93

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Phosphorylation of guanosine monophosphate reductase triggers a GTP-dependent switch from pro- to anti-oncogenic function of EPHA4.

Wolff DW, Deng Z, Bianchi-Smiraglia A, Foley CE, Han Z, Wang X, Shen S, Rosenberg MM, Moparthy S, Yun DH, Chen J, Baker BK, Roll MV, Magiera AJ, Li J, Hurley E, Feltri ML, Cox AO, Lee J, Furdui CM, Liu L, Bshara W, LaConte LEW, Kandel ES, Pasquale EB, Qu J, Hedstrom L, Nikiforov MA
Cell chemical biology 2022 Jun 16;29(6):970-984.e6

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Host Zinc-finger CCHC-type containing protein 3 inhibits pseudorabies virus proliferation by regulating type I interferon signaling.

Chen X, Shan T, Sun D, Zhai H, Dong S, Kong N, Zheng H, Tong W, Tong G
Gene 2022 Jun 15;827:146480

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Integrated analysis of tRNA-derived small RNAs in proliferative human aortic smooth muscle cells.

Zhao JZ, Li QY, Lin JJ, Yang LY, Du MY, Wang Y, Liu KX, Jiang ZA, Li HH, Wang SF, Sun B, Mu SQ, Li B, Liu K, Gong M, Sun SG
Cellular & molecular biology letters 2022 Jun 15;27(1):47

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JNK and Jag1/Notch2 co-regulate CXCL16 to facilitate cypermethrin-induced kidney damage.

Liu C, Wu M, Qu J, Huang X, Zeng Q, Ha M
Ecotoxicology and environmental safety 2022 Jun 15;238:113582

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Integrated metabolism and epigenetic modifications in the macrophages of mice in responses to cold stress.

Lu J, Fu S, Dai J, Hu J, Li S, Ji H, Wang Z, Yu J, Bao J, Xu B, Guo J, Yang H
Journal of Zhejiang University. Science. B 2022 Jun 15;23(6):461-480

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SARS-CoV-2 productively infects human brain microvascular endothelial cells.

Yang RC, Huang K, Zhang HP, Li L, Zhang YF, Tan C, Chen HC, Jin ML, Wang XR
Journal of neuroinflammation 2022 Jun 15;19(1):149

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Inhibition of the lncRNA MIAT prevents podocyte injury and mitotic catastrophe in diabetic nephropathy.

Wang Z, Chang Y, Liu Y, Liu B, Zhen J, Li X, Lin J, Yu Q, Lv Z, Wang R
Molecular therapy. Nucleic acids 2022 Jun 14;28:136-153

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Protective Effects of Liquiritigenin against Cisplatin-Induced Nephrotoxicity via NRF2/SIRT3-Mediated Improvement of Mitochondrial Function.

Zhou M, Dai Y, Ma Y, Yan Y, Hua M, Gao Q, Geng X, Zhou Q
Molecules (Basel, Switzerland) 2022 Jun 14;27(12)

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Resveratrol Induces Autophagy and Apoptosis in Non-Small-Cell Lung Cancer Cells by Activating the NGFR-AMPK-mTOR Pathway.

Li J, Fan Y, Zhang Y, Liu Y, Yu Y, Ma M
Nutrients 2022 Jun 10;14(12)

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NCAPH is a prognostic biomarker and associated with immune infiltrates in lung adenocarcinoma.

Li C, Meng J, Zhang T
Scientific reports 2022 Jun 10;12(1):9578

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The role of ER stress and ATP/AMPK in oxidative stress meditated hepatotoxicity induced by citrinin.

Wu J, Yang C, Yang M, Liang Z, Wu Y, Kong X, Fan H, Wang S, Ning C, Xiao W, Jin Y, Yi J, Yuan Z
Ecotoxicology and environmental safety 2022 Jun 1;237:113531

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High-frequency repetitive transcranial magnetic stimulation mitigates depression-like behaviors in CUMS-induced rats via FGF2/FGFR1/p-ERK signaling pathway.

Yan J, Zhang F, Niu L, Wang X, Lu X, Ma C, Zhang C, Song J, Zhang Z
Brain research bulletin 2022 Jun 1;183:94-103

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Large Yellow Tea Extract Ameliorates Metabolic Syndrome by Suppressing Lipogenesis through SIRT6/SREBP1 Pathway and Modulating Microbiota in Leptin Receptor Knockout Rats.

Wu G, Sun X, Cheng H, Xu S, Li D, Xie Z
Foods (Basel, Switzerland) 2022 Jun 1;11(11)

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Antioxidant potential of Pediococcus pentosaceus strains from the sow milk bacterial collection in weaned piglets.

Wang L, Liu Q, Chen Y, Zheng X, Wang C, Qi Y, Dong Y, Xiao Y, Chen C, Chen T, Huang Q, Zhai Z, Long C, Yang H, Li J, Wang L, Zhang G, Liao P, Liu YX, Huang P, Huang J, Wang Q, Chu H, Yin J, Yin Y
Microbiome 2022 Jun 1;10(1):83

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Hexokinase 2-mediated glycolysis promotes receptor activator of NF-κB ligand expression in Porphyromonas gingivalis lipopolysaccharide-treated osteoblasts.

Yu Y, Jiang L, Li J, Lei L, Li H
Journal of periodontology 2022 Jul;93(7):1036-1047

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miR-520d-3p/MIG-7 axis regulates vasculogenic mimicry formation and metastasis in osteosarcoma.

Yao N, Zhou J, Song J, Jiang Y, Zhang J
Neoplasma 2022 Jul;69(4):764-775

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Sema3A accelerates bone formation during distraction osteogenesis in mice.

Zhang N, Hua Y, Li Y, Pan J
Connective tissue research 2022 Jul;63(4):382-392

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Inhibition of nuclear deacetylase Sirtuin-1 induces mitochondrial acetylation and calcium overload leading to cell death.

Sun Y, Yang YM, Hu YY, Ouyang L, Sun ZH, Yin XF, Li N, He QY, Wang Y
Redox biology 2022 Jul;53:102334

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Dopamine 1 receptors inhibit apoptosis via activating CSE/H(2) S pathway in high glucose-induced vascular endothelial cells.

Li H, Wu R, Xi Y, Li H, Chang G, Sun F, Wei C, Jiao L, Wen X, Zhang G, Zaid A, Hao J
Cell biology international 2022 Jul;46(7):1098-1108

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In utero hypoxia attenuated acetylcholine-mediated vasodilatation via CHRM3/p-NOS3 in fetal sheep MCA: role of ROS/ERK1/2.

He Y, Su H, Li N, Zhang Y, Zhang P, Zhang Y, Ye Y, Zhang Y, Tang J, Xu Z
Hypertension research : official journal of the Japanese Society of Hypertension 2022 Jul;45(7):1168-1182

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Curcumin attenuates isoniazid-induced hepatotoxicity by upregulating the SIRT1/PGC-1α/NRF1 pathway.

Li Y, Luo WW, Cheng X, Xiang HR, He B, Zhang QZ, Peng WX
Journal of applied toxicology : JAT 2022 Jul;42(7):1192-1204

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PCDHB14 promotes ferroptosis and is a novel tumor suppressor in hepatocellular carcinoma.

Liu Y, Ouyang L, Mao C, Chen Y, Li T, Liu N, Wang Z, Lai W, Zhou Y, Cao Y, Liu S, Liang Y, Wang M, Liu S, Chen L, Shi Y, Xiao D, Tao Y
Oncogene 2022 Jul;41(27):3570-3583

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Podophyllotoxin-combined 5-aminolevulinic acid photodynamic therapy significantly promotes HR-HPV-infected cell death.

Wang J, Wang Q, Chen P, Li Q, Li Z, Xu M, Zeng K, Li C
Photodermatology, photoimmunology & photomedicine 2022 Jul;38(4):343-353

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Entacapone alleviates acute kidney injury by inhibiting ferroptosis.

Yang J, Sun X, Huang N, Li P, He J, Jiang L, Zhang X, Han S, Xin H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jul;36(7):e22399

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Periostin promotes nucleus pulposus cells apoptosis by activating the Wnt/β-catenin signaling pathway.

Zhu D, Wang Z, Zhang G, Ma C, Qiu X, Wang Y, Liu M, Guo X, Chen H, Deng Q, Kang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jul;36(7):e22369

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Trilobatin promotes angiogenesis after cerebral ischemia-reperfusion injury via SIRT7/VEGFA signaling pathway in rats.

Huang F, Luo L, Wu Y, Xia D, Xu F, Gao J, Shi J, Gong Q
Phytotherapy research : PTR 2022 Jul;36(7):2940-2951

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A dual crosslinked hydrogel-mediated integrated peptides and BMSC therapy for myocardial regeneration.

Zheng Z, Guo Z, Zhong F, Wang B, Liu L, Ma W, Yu CY, Wei H
Journal of controlled release : official journal of the Controlled Release Society 2022 Jul;347:127-142

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Prognostic and functional role of hyaluronan-binding protein 1 in pancreatic ductal adenocarcinoma.

Adachi Y, Sato N, Oba T, Amaike T, Kudo Y, Kohi S, Nakayama T, Hirata K
Oncology letters 2022 Jul;24(1):222

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Inhibition of Drp1 ameliorates diabetic retinopathy by regulating mitochondrial homeostasis.

Zhang MY, Zhu L, Bao X, Xie TH, Cai J, Zou J, Wang W, Gu S, Li Y, Li HY, Yao Y, Wei TT
Experimental eye research 2022 Jul;220:109095

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Inhibition of Cpt1a alleviates oxidative stress-induced chondrocyte senescence via regulating mitochondrial dysfunction and activating mitophagy.

Jiang N, Xing B, Peng R, Shang J, Wu B, Xiao P, Lin S, Xu X, Lu H
Mechanisms of ageing and development 2022 Jul;205:111688

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Elevation of N-acetyltransferase 10 in hippocampal neurons mediates depression- and anxiety-like behaviors.

Guo XF, Wang XH, Fu YL, Meng Q, Huang BY, Yang R, Guo Y, Du YR, Wang X, Gao Y, Song L, Gong M, Wang S, Li YD, Shi HS, Shi Y
Brain research bulletin 2022 Jul;185:91-98

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Newcastle disease virus degrades SIRT3 via PINK1-PRKN-dependent mitophagy to reprogram energy metabolism in infected cells.

Gong Y, Tang N, Liu P, Sun Y, Lu S, Liu W, Tan L, Song C, Qiu X, Liao Y, Yu S, Liu X, Lin SH, Ding C
Autophagy 2022 Jul;18(7):1503-1521

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Amentoflavone attenuates Listeria monocytogenes pathogenicity through an LLO-dependent mechanism.

Tingting W, Tianqi F, Xinyu W, Can Z, Xue S, Xuming D, Jianfeng W
British journal of pharmacology 2022 Jul;179(14):3839-3858

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The neuroprotective effects of GPR55 against hippocampal neuroinflammation and impaired adult neurogenesis in CSDS mice.

Shen SY, Yu R, Li W, Liang LF, Han QQ, Huang HJ, Li B, Xu SF, Wu GC, Zhang YQ, Yu J
Neurobiology of disease 2022 Jul;169:105743

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Hippocampal AMPA receptors mediate the impairment of spatial learning and memory in prenatally stressed offspring rats.

Yao D, Mu Y, Lu Y, Li L, Shao S, Zhou J, Li J, Chen S, Zhang D, Zhang Y, Zhu Z, Li H
Journal of psychiatric research 2022 Jul;151:17-24

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Dasatinib suppresses atherosclerotic lesions by suppressing cholesterol uptake in a mouse model of hypercholesterolemia.

Takaba M, Iwaki T, Arakawa T, Ono T, Maekawa Y, Umemura K
Journal of pharmacological sciences 2022 Jul;149(3):158-165

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Discovery of cinnamamide-barbiturate hybrids as a novel class of Nrf2 activator against myocardial ischemia/reperfusion injury.

Wei B, Zhang J, Li NN, Yang LH, Xu XL, Shi YY, Liu SH, Chen YJ
Bioorganic chemistry 2022 Jul;124:105828

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Targeting chemoresistance in Xp11.2 translocation renal cell carcinoma using a novel polyamide-chlorambucil conjugate.

Funasaki S, Mehanna S, Ma W, Nishizawa H, Kamikubo Y, Sugiyama H, Ikeda S, Motoshima T, Hasumi H, Linehan WM, Schmidt LS, Ricketts C, Suda T, Oike Y, Kamba T, Baba M
Cancer science 2022 Jul;113(7):2352-2367

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IL-17A drives cognitive aging probably via inducing neuroinflammation and theta oscillation disruption in the hippocampus.

Li Y, Mao M, Zhu L, Sun Q, Tong J, Zhou Z
International immunopharmacology 2022 Jul;108:108898

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Thiamine pretreatment improves endotoxemia-related liver injury and cholestatic complications by regulating galactose metabolism and inhibiting macrophage activation.

Li T, Bai J, Du Y, Tan P, Zheng T, Chen Y, Cheng Y, Cai T, Huang M, Fu W, Wen J
International immunopharmacology 2022 Jul;108:108892

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Pemafibrate attenuates pulmonary fibrosis by inhibiting myofibroblast differentiation.

Liu Y, Chen S, Yu L, Deng Y, Li D, Yu X, Chen D, Lu Y, Liu S, Chen R
International immunopharmacology 2022 Jul;108:108728

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Perilipin 5 protects against oxygen-glucose deprivation/reoxygenation-elicited neuronal damage by inhibiting oxidative stress and inflammatory injury via the Akt-GSK-3β-Nrf2 pathway.

Huo K, Ma KG, Guo QY, Duan P, Xu J
International immunopharmacology 2022 Jul;108:108718

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Cellular protein HSC70 promotes fowl adenovirus serotype 4 replication in LMH cells via interacting with viral 100K protein.

Gao S, Chen H, Zhang X, Zhao J, Wang Z
Poultry science 2022 Jul;101(7):101941

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Effect of starvation and refeeding on reactive oxygen species, autophagy and oxidative stress in Chinese perch (Siniperca chuatsi) muscle growth.

Wu P, Chen L, Cheng J, Pan Y, Zhu X, Chu W, Zhang J
Journal of fish biology 2022 Jul;101(1):168-178

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Gallic acid induces T-helper-1-like T(reg) cells and strengthens immune checkpoint blockade efficacy.

Deng B, Yang B, Chen J, Wang S, Zhang W, Guo Y, Han Y, Li H, Dang Y, Yuan Y, Dai X, Zang Y, Li Y, Li B
Journal for immunotherapy of cancer 2022 Jul;10(7)

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Induction of endothelial barrier dysfunction by serum factors in rats subjected to traumatic brain injury and hemorrhagic shock.

Ke Y, Proctor JL, Zhang C, Medina J, Miller CHT, Kim J, Grissom TE, Birukova AA, Fiskum GM, Birukov KG
Physiological reports 2022 Jul;10(13):e15350

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LncRNA HOTTIP PROMOTES OVARIAN CANCER CELL INVASION AND METASTASIS BY STABILIZING HIF-1α IN THE ANOXIC CELLULAR MICROENVIRONMENT.

Zhang S, Ma Q, Wu X, Chen P
Acta endocrinologica (Bucharest, Romania : 2005) 2022 Jul-Sep;18(3):263-270

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Gankyrin modulated non-small cell lung cancer progression via glycolysis metabolism in a YAP1-dependent manner.

Yu T, Liu Y, Xue J, Sun X, Zhu D, Ma L, Guo Y, Jin T, Cao H, Chen Y, Zhu T, Li X, Liang H, Du Z, Shan H
Cell death discovery 2022 Jul 9;8(1):312

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Hypoxia-Induced Scleral HIF-2α Upregulation Contributes to Rises in MMP-2 Expression and Myopia Development in Mice.

Wu W, Su Y, Hu C, Tao H, Jiang Y, Zhu G, Zhu J, Zhai Y, Qu J, Zhou X, Zhao F
Investigative ophthalmology & visual science 2022 Jul 8;63(8):2

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PFKM inhibits doxorubicin-induced cardiotoxicity by enhancing oxidative phosphorylation and glycolysis.

Zhou M, Sun X, Wang C, Wang F, Fang C, Hu Z
Scientific reports 2022 Jul 8;12(1):11684

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Duck Tembusu virus infection induces mitochondrial-mediated and death receptor-mediated apoptosis in duck embryo fibroblasts.

Pan Y, Cai W, Cheng A, Wang M, Chen S, Huang J, Yang Q, Wu Y, Sun D, Mao S, Zhu D, Liu M, Zhao X, Zhang S, Gao Q, Ou X, Tian B, Yin Z, Jia R
Veterinary research 2022 Jul 7;53(1):53

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Transcriptional landscape of human neuroblastoma cells in response to SARS-CoV-2.

Yang RC, Huang K, Zhang HP, Li L, Tan C, Chen HC, Jin ML, Wang XR
BMC neuroscience 2022 Jul 6;23(1):43

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Targeting BCAT1 Combined with α-Ketoglutarate Triggers Metabolic Synthetic Lethality in Glioblastoma.

Zhang B, Peng H, Zhou M, Bao L, Wang C, Cai F, Zhang H, Wang JE, Niu Y, Chen Y, Wang Y, Hatanpaa KJ, Copland JA, DeBerardinis RJ, Wang Y, Luo W
Cancer research 2022 Jul 5;82(13):2388-2402

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Human chorion-derived mesenchymal stem cells suppress JAK2/STAT3 signaling and induce apoptosis of cholangiocarcinoma cell lines.

Jantalika T, Manochantr S, Kheolamai P, Tantikanlayaporn D, Saijuntha W, Pinlaor S, Chairoungdua A, Paraoan L, Tantrawatpan C
Scientific reports 2022 Jul 5;12(1):11341

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20(S)-Protopanaxadiol decreases atherosclerosis in ApoE KO mice by increasing the levels of LDLR and inhibiting its binding with PCSK9.

Huang YW, Zhang M, Wang LT, Nie Y, Yang JB, Meng WL, Wang XJ, Sheng J
Food & function 2022 Jul 4;13(13):7020-7028

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Akkermansia muciniphila Colonization Alleviating High Fructose and Restraint Stress-Induced Jejunal Mucosal Barrier Disruption.

Yu J, Liu T, Gao Z, Liu R, Wang Z, Chen Y, Cao J, Dong Y
Nutrients 2022 Jul 30;14(15)

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Cholesterol sulfate alleviates ulcerative colitis by promoting cholesterol biosynthesis in colonic epithelial cells.

Xu D, Ma R, Ju Y, Song X, Niu B, Hong W, Wang R, Yang Q, Zhao Z, Zhang Y, Zheng Y, Bai Q, Lv M, Sun N, Li X
Nature communications 2022 Jul 30;13(1):4428

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LncRNA ANRIL mediates endothelial dysfunction through BDNF downregulation in chronic kidney disease.

Su H, Liu B, Chen H, Zhang T, Huang T, Liu Y, Wang C, Ma Q, Wang Q, Lv Z, Wang R
Cell death & disease 2022 Jul 29;13(7):661

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Pseudoislet Aggregation of Pancreatic β-Cells Improves Glucose Stimulated Insulin Secretion by Altering Glucose Metabolism and Increasing ATP Production.

Cornell D, Miwa S, Georgiou M, Anderson SJ, Honkanen-Scott M, Shaw JAM, Arden C
Cells 2022 Jul 29;11(15)

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BAP1 Loss Promotes Suppressive Tumor Immune Microenvironment via Upregulation of PROS1 in Class 2 Uveal Melanomas.

Kaler CJ, Dollar JJ, Cruz AM, Kuznetsoff JN, Sanchez MI, Decatur CL, Licht JD, Smalley KSM, Correa ZM, Kurtenbach S, Harbour JW
Cancers 2022 Jul 28;14(15)

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Dabie bandavirus Nonstructural Protein Interacts with Actin to Induce F-Actin Rearrangement and Inhibit Viral Adsorption and Entry.

Liu H, Liu S, Liu Z, Gao X, Xu L, Huang M, Su Y, Wang Z, Wang T
Journal of virology 2022 Jul 27;96(14):e0078822

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Effects of Artemisinin on Escherichia coli-Induced Mastitis in Bovine Mammary Epithelial Cells and Mice.

Li Z, Hu J, Wang X, Du Y, Yin J, Gao J, Han B, Cui S, Liu Y, Liu J
Veterinary sciences 2022 Jul 26;9(8)

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HDAC2- and EZH2-Mediated Histone Modifications Induce PDK1 Expression through miR-148a Downregulation in Breast Cancer Progression and Adriamycin Resistance.

Xie Y, Shi Z, Qian Y, Jiang C, Liu W, Liu B, Jiang B
Cancers 2022 Jul 23;14(15)

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Enhancement of Osteoblast Function through Extracellular Vesicles Derived from Adipose-Derived Stem Cells.

Ho ML, Hsu CJ, Wu CW, Chang LH, Chen JW, Chen CH, Huang KC, Chang JK, Wu SC, Shao PL
Biomedicines 2022 Jul 21;10(7)

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Prefrontal GABA(A)(δ)R Promotes Fear Extinction through Enabling the Plastic Regulation of Neuronal Intrinsic Excitability.

Pan HQ, Liu XX, He Y, Zhou J, Liao CZ, You WJ, Jiang SY, Qin X, Chen WB, Fei EK, Zhang WH, Pan BX
The Journal of neuroscience : the official journal of the Society for Neuroscience 2022 Jul 20;42(29):5755-5770

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GRP75-driven, cell-cycle-dependent macropinocytosis of Tat/pDNA-Ca(2+) nanoparticles underlies distinct gene therapy effect in ovarian cancer.

Su L, Sun Z, Qi F, Su H, Qian L, Li J, Zuo L, Huang J, Yu Z, Li J, Chen Z, Zhang S
Journal of nanobiotechnology 2022 Jul 20;20(1):340

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Thiostrepton induces ferroptosis in pancreatic cancer cells through STAT3/GPX4 signalling.

Zhang W, Gong M, Zhang W, Mo J, Zhang S, Zhu Z, Wang X, Zhang B, Qian W, Wu Z, Ma Q, Wang Z
Cell death & disease 2022 Jul 20;13(7):630

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The E3 ubiquitin ligase MG53 inhibits hepatocellular carcinoma by targeting RAC1 signaling.

Ma X, Ma X, Zhu L, Zhao Y, Chen M, Li T, Lin Y, Ma D, Sun C, Han L
Oncogenesis 2022 Jul 20;11(1):40

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β-Caryophyllene suppresses ferroptosis induced by cerebral ischemia reperfusion via activation of the NRF2/HO-1 signaling pathway in MCAO/R rats.

Hu Q, Zuo T, Deng L, Chen S, Yu W, Liu S, Liu J, Wang X, Fan X, Dong Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul 20;102:154112

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Bisdemethoxycurcumin Attenuated Renal Injury via Activation of Keap1/Nrf2 Pathway in High-Fat Diet-Fed Mice.

Ding X, Chen Y, Zhou L, Wu R, Jian T, Lyu H, Liu Y, Chen J
International journal of molecular sciences 2022 Jul 2;23(13)

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Pseudorabies Virus Tegument Protein UL13 Suppresses RLR-Mediated Antiviral Innate Immunity through Regulating Receptor Transcription.

Zhao N, Wang F, Kong Z, Shang Y
Viruses 2022 Jul 2;14(7)

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N-glycosylation of GDF15 abolishes its inhibitory effect on EGFR in AR inhibitor-resistant prostate cancer cells.

Wang R, Wen P, Yang G, Feng Y, Mi Y, Wang X, Zhu S, Chen YQ
Cell death & disease 2022 Jul 19;13(7):626

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Viral evasion of PKR restriction by reprogramming cellular stress granules.

Gao P, Liu Y, Wang H, Chai Y, Weng W, Zhang Y, Zhou L, Ge X, Guo X, Han J, Yang H
Proceedings of the National Academy of Sciences of the United States of America 2022 Jul 19;119(29):e2201169119

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Proteomic Mapping and Targeting of Mitotic Pericentriolar Material in Tumors Bearing Centrosome Amplification.

Xie B, Pu Y, Yang F, Chen W, Yue W, Ma J, Zhang N, Jiang Y, Wu J, Lin Y, Liang X, Wang C, Zou P, Li M
Cancer research 2022 Jul 18;82(14):2576-2592

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Iron deficiency exacerbates aortic medial degeneration by inducing excessive mitochondrial fission.

Zhong X, Wu Q, Wang Z, Zhang M, Zheng S, Shi F, Chen Y, Che Y, Yuan S, Xing K
Food & function 2022 Jul 18;13(14):7666-7683

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Nicotinamide mononucleotide supplementation protects the intestinal function in aging mice and D-galactose induced senescent cells.

Ru M, Wang W, Zhai Z, Wang R, Li Y, Liang J, Kothari D, Niu K, Wu X
Food & function 2022 Jul 18;13(14):7507-7519

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Effect of Qingyangshen glycosides on social defeat mice model.

Liu D, Wang J, Chang L, Zhu Q, Jiang N, Azhar M, Zeng G
Journal of ethnopharmacology 2022 Jul 15;293:115253

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Sulfate oligosaccharide of Gracilaria lemaneiformis modulates type 1 immunity by restraining T cell activation.

Liu Q, Zhou Y, Ma L, Gu F, Liao K, Liu Y, Zhang Y, Liu H, Hong Y, Cao M, Liu WH, Liu C, Liu G
Carbohydrate polymers 2022 Jul 15;288:119377

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The role of ciliopathy-associated type 3 adenylyl cyclase in infanticidal behavior in virgin adult male mice.

Wu X, Yang D, Zhou Y, Li S, Wang Z
iScience 2022 Jul 15;25(7):104534

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N6-methyladenosine RNA demethylase ALKBH5 is testis-specifically downregulated in hybrid male sterile dzo and is a target gene of bta-miR-200a.

Chen H, Zhang J, Yan Y, Zhu C, Wang L, Fu S, Zuo F, Zhang GW
Theriogenology 2022 Jul 15;187:51-57

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Monitoring Protein Import into the Endoplasmic Reticulum in Living Cells with Proximity Labeling.

Lyu Z, Sycks MM, Espinoza MF, Nguyen KK, Montoya MR, Galapate CM, Mei L, Genereux JC
ACS chemical biology 2022 Jul 15;17(7):1963-1977

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KIFC3 promotes proliferation, migration and invasion of esophageal squamous cell carcinoma cells by activating EMT and β-catenin signaling.

Hao WW, Xu F
World journal of gastrointestinal oncology 2022 Jul 15;14(7):1239-1251

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CCL20/CCR6 axis mediates macrophages to promote proliferation and migration of ESCs by blocking autophagic flux in endometriosis.

Tan J, Xu T, Gou Y, Wang H, Liang Z, Cao Y, Wang H, Yu Y, Jiao N, Zhang Z
Stem cell research & therapy 2022 Jul 15;13(1):294

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Structure-Based Discovery of a Series of NSD2-PWWP1 Inhibitors.

Li N, Yang H, Liu K, Zhou L, Huang Y, Cao D, Li Y, Sun Y, Yu A, Du Z, Yu F, Zhang Y, Wang B, Geng M, Li J, Xiong B, Xu S, Huang X, Liu T
Journal of medicinal chemistry 2022 Jul 14;65(13):9459-9477

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Chronic stress-induced depression requires the recruitment of peripheral Th17 cells into the brain.

Peng Z, Peng S, Lin K, Zhao B, Wei L, Tuo Q, Liao D, Yuan T, Shi Z
Journal of neuroinflammation 2022 Jul 14;19(1):186

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ZEB2/TWIST1/PRMT5/NuRD Multicomplex Contributes to the Epigenetic Regulation of EMT and Metastasis in Colorectal Carcinoma.

Zheng Y, Dai M, Dong Y, Yu H, Liu T, Feng X, Yu B, Zhang H, Wu J, Kong W, Yu X, Wu H
Cancers 2022 Jul 14;14(14)

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FUBP3 Degrades the Porcine Epidemic Diarrhea Virus Nucleocapsid Protein and Induces the Production of Type I Interferon.

Dong S, Kong N, Wang C, Li Y, Sun D, Qin W, Zhai H, Zhai X, Yang X, Ye C, Ye M, Liu C, Yu L, Zheng H, Tong W, Yu H, Zhang W, Tong G, Shan T
Journal of virology 2022 Jul 13;96(13):e0061822

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Nonstructural Protein NSs Activates Inflammasome and Pyroptosis through Interaction with NLRP3 in Human Microglial Cells Infected with Severe Fever with Thrombocytopenia Syndrome Bandavirus.

Gao C, Yu Y, Wen C, Li Z, Ding H, Qi X, Cardona CJ, Xing Z
Journal of virology 2022 Jul 13;96(13):e0016722

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Quantitative proteomic analysis of Bi Zhong Xiao decoction against collagen-induced arthritis rats in the early and late stages.

He C, Wang Y, Wen Y, Li T, Hu E, Zeng S, Xiong X
BMC complementary medicine and therapies 2022 Jul 13;22(1):186

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Transient neuroinflammation following surgery contributes to long-lasting cognitive decline in elderly rats via dysfunction of synaptic NMDA receptor.

Chen B, Qin G, Xiao J, Deng X, Lin A, Liu H
Journal of neuroinflammation 2022 Jul 13;19(1):181

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Mitochondrial Calcium-Triggered Oxidative Stress and Developmental Defects in Dopaminergic Neurons Differentiated from Deciduous Teeth-Derived Dental Pulp Stem Cells with MFF Insufficiency.

Sun X, Dong S, Kato H, Kong J, Ito Y, Hirofuji Y, Sato H, Kato TA, Sakai Y, Ohga S, Fukumoto S, Masuda K
Antioxidants (Basel, Switzerland) 2022 Jul 13;11(7)

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PRIM2 Promotes Cell Cycle and Tumor Progression in p53-Mutant Lung Cancer.

Wang T, Tang T, Jiang Y, He T, Qi L, Chang H, Qiao Y, Sun M, Shan C, Zhu X, Liu J, Wang J
Cancers 2022 Jul 11;14(14)

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TFRC upregulation promotes ferroptosis in CVB3 infection via nucleus recruitment of Sp1.

Yi L, Hu Y, Wu Z, Li Y, Kong M, Kang Z, Zuoyuan B, Yang Z
Cell death & disease 2022 Jul 11;13(7):592

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Blocking glycine utilization inhibits multiple myeloma progression by disrupting glutathione balance.

Xia J, Zhang J, Wu X, Du W, Zhu Y, Liu X, Liu Z, Meng B, Guo J, Yang Q, Wang Y, Wang Q, Feng X, Xie G, Shen Y, He Y, Xiang J, Wu M, An G, Qiu L, Jia W, Zhou W
Nature communications 2022 Jul 11;13(1):4007

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SULF2 enhances GDF15-SMAD axis to facilitate the initiation and progression of pancreatic cancer.

He R, Shi J, Xu D, Yang J, Shen Y, Jiang YS, Tao L, Yang M, Fu X, Yang JY, Liu D, Huo Y, Shen X, Lu P, Niu N, Sun YW, Xue J, Liu W
Cancer letters 2022 Jul 10;538:215693

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Combined exposure of lead and high-fat diet enhanced cognitive decline via interacting with CREB-BDNF signaling in male rats.

Liu R, Bai L, Liu M, Wang R, Wu Y, Li Q, Ba Y, Zhang H, Zhou G, Yu F, Huang H
Environmental pollution (Barking, Essex : 1987) 2022 Jul 1;304:119200

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Interleukin 7 inhibit autophagy via P53 regulated AMPK/mTOR signaling pathway in non-small cell lung cancer.

Zhu Y, Jiang X, Ding Z, Ming J
Scientific reports 2022 Jul 1;12(1):11208

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Activated AXL Protects Against Hepatic Ischemia-reperfusion Injury by Upregulating SOCS-1 Expression.

Wang Z, Liu D, Yan Q, Liu F, Zhan M, Qi S, Fang Q, Yao L, Wang W, Zhang R, Du J, Chen L
Transplantation 2022 Jul 1;106(7):1351-1364

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Knockdown of GBP1 inhibits BCG-induced apoptosis in macrophage RAW 264.7 cells via p38/JNK pathway.

Wang J, Liu Z, Li W, Yu J, Zhang D
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2022 Jan;97:105158

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Rosmarinic Acid Decreases the Malignancy of Pancreatic Cancer Through Inhibiting Gli1 Signaling.

Zhou X, Wang W, Li Z, Chen L, Wen C, Ruan Q, Xu Z, Liu R, Xu J, Bai Y, Deng J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153861

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Moringa oleifera Lam. seed extract protects kidney function in rats with diabetic nephropathy by increasing GSK-3β activity and activating the Nrf2/HO-1 pathway.

Wen Y, Liu Y, Huang Q, Liu R, Liu J, Zhang F, Liu S, Jiang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153856

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Ciliary Type III Adenylyl Cyclase in the VMH Is Crucial for High-Fat Diet-Induced Obesity Mediated by Autophagy.

Yang D, Wu X, Wang W, Zhou Y, Wang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jan;9(3):e2102568

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Ror2 mediates chronic post-thoracotomy pain by inducing the transformation of A1/A2 reactive astrocytes in rats.

Liu C, Shen L, Xu L, Zhu A, Huang Y
Cellular signalling 2022 Jan;89:110183

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Galactose-decorated liver tumor-specific nanoliposomes incorporating selective BRD4-targeted PROTAC for hepatocellular carcinoma therapy.

Saraswat A, Vemana HP, Dukhande VV, Patel K
Heliyon 2022 Jan;8(1):e08702

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Resveratrol Improves Synaptic Plasticity in Hypoxic-Ischemic Brain Injury in Neonatal Mice via Alleviating SIRT1/NF-κB Signaling-Mediated Neuroinflammation.

Peng X, Wang J, Peng J, Jiang H, Le K
Journal of molecular neuroscience : MN 2022 Jan;72(1):113-125

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Inflammatory cell-derived CXCL3 promotes pancreatic cancer metastasis through a novel myofibroblast-hijacked cancer escape mechanism.

Sun X, He X, Zhang Y, Hosaka K, Andersson P, Wu J, Wu J, Jing X, Du Q, Hui X, Ding B, Guo Z, Hong A, Liu X, Wang Y, Ji Q, Beyaert R, Yang Y, Li Q, Cao Y
Gut 2022 Jan;71(1):129-147

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A calcium phosphate drug carrier loading with 5-fluorouracil achieving a synergistic effect for pancreatic cancer therapy.

Chen J, Qiu M, Zhang S, Li B, Li D, Huang X, Qian Z, Zhao J, Wang Z, Tang D
Journal of colloid and interface science 2022 Jan;605:263-273

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Exosomes from dental pulp cells attenuate bone loss in mouse experimental periodontitis.

Shimizu Y, Takeda-Kawaguchi T, Kuroda I, Hotta Y, Kawasaki H, Hariyama T, Shibata T, Akao Y, Kunisada T, Tatsumi J, Tezuka KI
Journal of periodontal research 2022 Jan;57(1):162-172

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Sorafenib attenuates liver fibrosis by triggering hepatic stellate cell ferroptosis via HIF-1α/SLC7A11 pathway.

Yuan S, Wei C, Liu G, Zhang L, Li J, Li L, Cai S, Fang L
Cell proliferation 2022 Jan;55(1):e13158

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Vps34 Inhibits Hepatocellular Carcinoma Invasion by Regulating Endosome-Lysosome Trafficking via Rab7-RILP and Rab11.

Qi C, Zou L, Wang S, Mao X, Hu Y, Shi J, Zhang Z, Wu H
Cancer research and treatment 2022 Jan;54(1):182-198

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Sestrin2 induction contributes to anti-inflammatory responses and cell survival by globular adiponectin in macrophages.

Lee S, Pham DV, Park PH
Archives of pharmacal research 2022 Jan;45(1):38-50

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Harmine is an effective therapeutic small molecule for the treatment of cardiac hypertrophy.

Huang J, Liu Y, Chen JX, Lu XY, Zhu WJ, Qin L, Xun ZX, Zheng QY, Li EM, Sun N, Xu C, Chen HY
Acta pharmacologica Sinica 2022 Jan;43(1):50-63

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SIRT1 induces the accumulation of TAMs at colorectal cancer tumor sites via the CXCR4/CXCL12 axis.

Fang H, Huang Y, Luo Y, Tang J, Yu M, Zhang Y, Zhong M
Cellular immunology 2022 Jan;371:104458

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The double-edged sword role of TGF-β signaling pathway between intrauterine inflammation and cranial neural crest development.

Li H, Long D, Lv G, Cheng X, Wang G, Yang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jan;36(1):e22113

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Alnustone inhibits the growth of hepatocellular carcinoma via ROS- mediated PI3K/Akt/mTOR/p70S6K axis.

Wang L, Cheng L, Ma L, Ahmad Farooqi A, Qiao G, Zhang Y, Ye H, Liu M, Huang J, Yang X, Lin X, Cao S
Phytotherapy research : PTR 2022 Jan;36(1):525-542

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Inhibition of progesterone receptor membrane component-1 exacerbates neonatal hypoxic-ischemic cerebral damage in male mice.

Sun X, Hu Y, Zhou H, Wang S, Zhou C, Lin L, Zhu T, Ge J, Han J, Zhou Y, Jin G, Wang Y, Zu J, Shi H, Yang X, Zan K, Wang J, Hua F
Experimental neurology 2022 Jan;347:113893

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ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1.

Zhang T, Sun L, Hao Y, Suo C, Shen S, Wei H, Ma W, Zhang P, Wang T, Gu X, Li ST, Chen Z, Yan R, Zhang Y, Cai Y, Zhou R, Jia W, Huang F, Gao P, Zhang H
Nature cancer 2022 Jan;3(1):75-89

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The deubiquitinase USP28 stabilizes the expression of RecQ family helicases and maintains the viability of triple negative breast cancer cells.

Wang J, Dong Y, Ma H, Wu L, Zhen X, Tang L, Jin J, Han S, Zhang P, Peng J
The Journal of biological chemistry 2022 Jan;298(1):101443

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Electroacupuncture alleviates spatial memory deficits in METH withdrawal mice by enhancing astrocyte-mediated glutamate clearance in the dCA1.

He T, Li N, Shi P, Xu X, Nie J, Lu X, Yu P, Fan Y, Ge F, Guan X
Addiction biology 2022 Jan;27(1):e13068

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Bcl-2 hijacks the arsenic trioxide resistance in SH-SY5Y cells.

Wang J, Peng X, Yang D, Guo M, Xu X, Yin F, Wang Y, Huang J, Zhan L, Qi Z
Journal of cellular and molecular medicine 2022 Jan;26(2):563-569

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Immunoproteasome modulates NLRP3 inflammasome-mediated neuroinflammation under cerebral ischaemia and reperfusion conditions.

Chen X, Wang Y, Yao N, Lin Z
Journal of cellular and molecular medicine 2022 Jan;26(2):462-474

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C1632 suppresses the migration and proliferation of non-small-cell lung cancer cells involving LIN28 and FGFR1 pathway.

Chen JY, Chen YJ, Liu L, Jin XX, Shen Z, Chen WB, Yang T, Xu SB, Wang GB, Cheng YN, Cheng DZ, Liu ZG, Zheng XH
Journal of cellular and molecular medicine 2022 Jan;26(2):422-435

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Caveolin-1 negatively regulates inflammation and fibrosis in silicosis.

He R, Yuan X, Lv X, Liu Q, Tao L, Meng J
Journal of cellular and molecular medicine 2022 Jan;26(1):99-107

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The critical role of B4GALT4 in promoting microtubule spindle assembly in HCC through the regulation of PLK1 and RHAMM expression.

Dai Z, Wang K, Gao Y
Journal of cellular physiology 2022 Jan;237(1):617-636

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Role and mechanism of the Dectin-1-mediated Syk/NF-κB signaling pathway in Talaromyces marneffei infection.

Peng Y, Chen Y, Ma J, Zhou W, Wang Y, Wang Y, Zheng H, Shi W
Experimental and therapeutic medicine 2022 Jan;23(1):84

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Zinc-finger protein 750 mitigates malignant biological behavior of oral CSC-like cells enriched from parental CAL-27 cells.

Xu C, Yang HL, Yang YK, Pan L, Chen HY
Oncology letters 2022 Jan;23(1):28

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DNMT3B regulates proliferation of A549 cells through the microRNA-152-3p/NCAM1 pathway.

Yang B, Huang S, Chen H, Li R, Hou S, Zhao J, Li Y
Oncology letters 2022 Jan;23(1):11

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Deubiquitinase USP13 promotes the epithelial-mesenchymal transition and metastasis in gastric cancer by maintaining Snail protein.

Zhang T, Zheng J, Qiao L, Zhao W
Pathology, research and practice 2022 Jan;229:153705

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Topical retinoic acid induces corneal strengthening by upregulating transglutaminase 2 in murine cornea.

Wu J, Wang J, Wang L, Huang Y
Experimental eye research 2022 Jan;214:108850

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Morphological changes of macrophages and their potential contribution to tendon healing.

Yang QQ, Zhang L, Zhou YL, Tang JB
Colloids and surfaces. B, Biointerfaces 2022 Jan;209(Pt 1):112145

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MICAL1 inhibits colorectal cancer cell migration and proliferation by regulating the EGR1/β-catenin signaling pathway.

Gu H, Li Y, Cui X, Cao H, Hou Z, Ti Y, Liu D, Gao J, Wang Y, Wen P
Biochemical pharmacology 2022 Jan;195:114870

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METTL3 Regulates Liver Homeostasis, Hepatocyte Ploidy, and Circadian Rhythm-Controlled Gene Expression in Mice.

Barajas JM, Lin CH, Sun HL, Alencastro F, Zhu AC, Aljuhani M, Navari L, Yilmaz SA, Yu L, Corps K, He C, Duncan AW, Ghoshal K
The American journal of pathology 2022 Jan;192(1):56-71

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Pyridoxamine ameliorates methylglyoxal-induced macrophage dysfunction to facilitate tissue repair in diabetic wounds.

Jiang M, Yakupu A, Guan H, Dong J, Liu Y, Song F, Tang J, Tian M, Niu Y, Lu S
International wound journal 2022 Jan;19(1):52-63

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RNF2 promotes the progression of colon cancer by regulating ubiquitination and degradation of IRF4.

Wang J, Ouyang X, Zhou Z, Mao S, Niu X, Li H, Xu W, Song Y, Cao J, Lai B
Biochimica et biophysica acta. Molecular cell research 2022 Jan;1869(1):119162

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Carrier-Free Delivery of Ultrasmall π-Conjugated Oligomer Nanoparticles with Photothermal Conversion over 80% for Cancer Theranostics.

Zheng R, Zhao Q, Qing W, Li S, Liu Z, Li Q, Huang Y
Small (Weinheim an der Bergstrasse, Germany) 2022 Jan;18(4):e2104521

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Silencing TXNIP ameliorates high uric acid-induced insulin resistance via the IRS2/AKT and Nrf2/HO-1 pathways in macrophages.

Yu W, Chen C, Zhuang W, Wang W, Liu W, Zhao H, Lv J, Xie D, Wang Q, He F, Xu C, Chen B, Yamamoto T, Koyama H, Cheng J
Free radical biology & medicine 2022 Jan;178:42-53

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Silent information regulator 1 ameliorates oxidative stress injury via PGC-1α/PPARγ-Nrf2 pathway after ischemic stroke in rat.

Zhou Y, Peng L, Li Y, Zhao Y
Brain research bulletin 2022 Jan;178:37-48

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Mettl3 inhibits the apoptosis and autophagy of chondrocytes in inflammation through mediating Bcl2 stability via Ythdf1-mediated m(6)A modification.

He Y, Wang W, Xu X, Yang B, Yu X, Wu Y, Wang J
Bone 2022 Jan;154:116182

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Overexpression of DOCK6 in oral squamous cell cancer promotes cellular migration and invasion and is associated with poor prognosis.

Zhang ZY, Sun YY, Wang HC, Fu WN, Sun CF
Archives of oral biology 2022 Jan;133:105297

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Injectable hyaluronic acid hydrogel loaded with BMSC and NGF for traumatic brain injury treatment.

Wang L, Zhang D, Ren Y, Guo S, Li J, Ma S, Yao M, Guan F
Materials today. Bio 2022 Jan;13:100201

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Characterization and function of mandarin fish c-Myc during viral infection process.

Ye C, Li N, Niu Y, Lin Q, Luo X, Liang H, Liu L, Fu X
Fish & shellfish immunology 2022 Jan;120:686-694

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Lysyl oxidase promotes anaplastic thyroid carcinoma cell proliferation and metastasis mediated via BMP1.

Liu Y, Zhang Y, Tan Z, Wang J, Hu Y, Sun J, Bao M, Huang P, Ge M, Chai YJ, Zheng C
Gland surgery 2022 Jan;11(1):245-257

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Cotargeting of Bcl-2 and Mcl-1 shows promising antileukemic activity against AML cells including those with acquired cytarabine resistance.

Liu F, Zhao Q, Su Y, Lv J, Gai Y, Liu S, Lin H, Wang Y, Wang G
Experimental hematology 2022 Jan;105:39-49

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BPIFA2 as a Novel Early Biomarker to Identify Fatal Radiation Injury After Radiation Exposure.

He L, Zhou S, Li W, Wang Q, Qi Z, Zhou P, Wang Z, Chen J, Li Y, Lin Z
Dose-response : a publication of International Hormesis Society 2022 Jan-Mar;20(1):15593258221086478

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Effect of Ultraviolet B Irradiation on Melanin Content Accompanied by the Activation of p62/GATA4-Mediated Premature Senescence in HaCaT Cells.

Yan J, Ma LP, Liu F, Sun B, Tian M, Lu X, Liu HX, Gao L, Liu QJ
Dose-response : a publication of International Hormesis Society 2022 Jan-Mar;20(1):15593258221075321

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Enhancement of Acylcarnitine Levels in Small Intestine of Abdominal Irradiation Rats Might Relate to Fatty Acid β-Oxidation Pathway Disequilibration.

Liu HX, Lu X, Zhao H, Li S, Gao L, Tian M, Liu QJ
Dose-response : a publication of International Hormesis Society 2022 Jan-Mar;20(1):15593258221075118

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HSP90AB1 Promotes the Proliferation, Migration, and Glycolysis of Head and Neck Squamous Cell Carcinoma.

Zhang H, Yin X, Zhang X, Zhou M, Xu W, Wei Z, Song C, Han S, Han W
Technology in cancer research & treatment 2022 Jan-Dec;21:15330338221118202

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Spinal 5-HT(2A) receptor is involved in electroacupuncture inhibition of chronic pain.

Yuan XC, Wang YY, Tian LX, Yan XJ, Guo YX, Zhao YL, Baba SS, Jia H, Wang HS, Li M, Huo FQ
Molecular pain 2022 Jan-Dec;18:17448069221087583

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A virulence factor as a therapeutic: the probiotic Enterococcus faecium SF68 arginine deiminase inhibits innate immune signaling pathways.

Ghazisaeedi F, Meens J, Hansche B, Maurischat S, Schwerk P, Goethe R, Wieler LH, Fulde M, Tedin K
Gut microbes 2022 Jan-Dec;14(1):2106105

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ROS/PI3K/Akt and Wnt/β-catenin signalings activate HIF-1α-induced metabolic reprogramming to impart 5-fluorouracil resistance in colorectal cancer.

Dong S, Liang S, Cheng Z, Zhang X, Luo L, Li L, Zhang W, Li S, Xu Q, Zhong M, Zhu J, Zhang G, Hu S
Journal of experimental & clinical cancer research : CR 2022 Jan 8;41(1):15

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ERK/p38/ROS burst responses to environmentally relevant concentrations of diphenyl phosphate-evoked neutrophil extracellular traps formation: Assessing the role of autophagy.

Li S, Ma Y, Ye S, Hu D, Xiao F
Journal of hazardous materials 2022 Jan 5;421:126758

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CHMFL-BMX-078, a BMX inhibitor, overcomes the resistance of melanoma to vemurafenib via inhibiting AKT pathway.

Jiang S, Jiang T, Huang H, Chen X, Li L, Wang Z, Fei J, Liu C, Liu Z, Cheng Y
Chemico-biological interactions 2022 Jan 5;351:109747

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High salt activates p97 to reduce host antiviral immunity by restricting Viperin induction.

Yuan Y, Miao Y, Ren T, Huang F, Qian L, Chen X, Zuo Y, Zhang HG, He J, Qiao C, Du Q, Wu Q, Zhang W, Zhu C, Xu Y, Wu D, Shi W, Jiang J, Xu G, Zheng H
EMBO reports 2022 Jan 5;23(1):e53466

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Novel 5-fluorouracil sensitizers for colorectal cancer therapy: Design and synthesis of S1P receptor 2 (S1PR2) antagonists.

Luo D, Guo Z, Zhao X, Wu L, Liu X, Zhang Y, Zhang Y, Deng Z, Qu X, Cui S, Wan S
European journal of medicinal chemistry 2022 Jan 5;227:113923

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SIRT6 protects vascular smooth muscle cells from osteogenic transdifferentiation via Runx2 in chronic kidney disease.

Li W, Feng W, Su X, Luo D, Li Z, Zhou Y, Zhu Y, Zhang M, Chen J, Liu B, Huang H
The Journal of clinical investigation 2022 Jan 4;132(1)

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Urolithin A protects dopaminergic neurons in experimental models of Parkinson's disease by promoting mitochondrial biogenesis through the SIRT1/PGC-1α signaling pathway.

Liu J, Jiang J, Qiu J, Wang L, Zhuo J, Wang B, Sun D, Yu S, Lou H
Food & function 2022 Jan 4;13(1):375-385

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The association of telomere maintenance and TERT expression with susceptibility to human papillomavirus infection in cervical epithelium.

Wang LN, Wang L, Cheng G, Dai M, Yu Y, Teng G, Zhao J, Xu D
Cellular and molecular life sciences : CMLS 2022 Jan 31;79(2):110

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m6A modifications regulate intestinal immunity and rotavirus infection.

Wang A, Tao W, Tong J, Gao J, Wang J, Hou G, Qian C, Zhang G, Li R, Wang D, Ren X, Zhang K, Ding S, Flavell RA, Li H, Pan W, Zhu S
eLife 2022 Jan 31;11

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Metastasis suppressor 1 controls osteoblast differentiation and bone homeostasis through regulating Src-Wnt/β-catenin signaling.

Chen M, Shan L, Gan Y, Tian L, Zhou J, Zhu E, Yuan H, Li X, Wang B
Cellular and molecular life sciences : CMLS 2022 Jan 30;79(2):107

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Saponins from Nigella glandulifera seeds attenuate collagen-induced rheumatoid arthritis in rats via the OPG/RANKL/NF-κB and Ang/Tie-2 pathways.

Jiang H, Xu F, Zeng L, Li C, Chen Y, Wang L, Li Z, Liu R
Journal of ethnopharmacology 2022 Jan 30;283:114714

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Guizhi-Shaoyao-Zhimu decoction attenuates monosodium urate crystal-induced inflammation through inactivation of NF-κB and NLRP3 inflammasome.

Zhou GQ, Chen G, Yang J, Qin WY, Ping J
Journal of ethnopharmacology 2022 Jan 30;283:114707

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The ethanol extract of flower buds of Tussilago farfara L. attenuates cigarette smoke-induced lung inflammation through regulating NLRP3 inflammasome, Nrf2, and NF-κB.

Xu LT, Wang T, Fang KL, Zhao Y, Wang XN, Ren DM, Shen T
Journal of ethnopharmacology 2022 Jan 30;283:114694

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A Novel Rat Model of Dry Eye Induced by Aerosol Exposure of Particulate Matter.

Mu N, Wang H, Chen D, Wang F, Ji L, Zhang C, Li M, Lu P
Investigative ophthalmology & visual science 2022 Jan 3;63(1):39

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Ketogenic diet ameliorates lipid dysregulation in type 2 diabetic mice by downregulating hepatic pescadillo 1.

Zhou J, Lu Y, Jia Y, Lu J, Jiang Z, Chen K
Molecular medicine (Cambridge, Mass.) 2022 Jan 3;28(1):1

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CBX4-dependent regulation of HDAC3 nuclear translocation reduces Bmp2-induced osteoblastic differentiation and calcification in adamantinomatous craniopharyngioma.

Yan X, Kang D, Lin Y, Qi S, Jiang C
Cell communication and signaling : CCS 2022 Jan 3;20(1):3

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Hyaluronic Acid-Modified Nanoparticles Self-Assembled from Linoleic Acid-Conjugated Chitosan for the Codelivery of miR34a and Doxorubicin in Resistant Breast Cancer.

Yang X, Shang P, Ji J, Malichewe C, Yao Z, Liao J, Du D, Sun C, Wang L, Tang YJ, Guo X
Molecular pharmaceutics 2022 Jan 3;19(1):2-17

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Long non-coding RNA lncC11orf54-1 modulates neuroinflammatory responses by activating NF-κB signaling during meningitic Escherichia coli infection.

Xu B, Yang R, Yang B, Li L, Chen J, Fu J, Qu X, Huo D, Tan C, Chen H, Peng Z, Wang X
Molecular brain 2022 Jan 3;15(1):4

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Ginsenoside compound K acts via LRP1 to alleviate Amyloid β(42)-induced neuroinflammation in microglia by suppressing NF-κB.

Jiao H, Jia J
Biochemical and biophysical research communications 2022 Jan 29;590:14-19

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Actin nucleator formins regulate the tension-buffering function of caveolin-1.

Shi X, Tang D, Xing Y, Zhao S, Fan C, Zhong J, Cui Y, Shi K, Jiu Y
Journal of molecular cell biology 2022 Jan 29;13(12):876-888

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LINC01119 negatively regulates osteogenic differentiation of mesenchymal stem cells via the Wnt pathway by targeting FZD4.

Gao H, Dong H, Zheng J, Jiang X, Gong M, Hu L, He J, Wang Y
Stem cell research & therapy 2022 Jan 29;13(1):43

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Steroid-sensitive nephrotic syndrome candidate gene CLVS1 regulates podocyte oxidative stress and endocytosis.

Lane BM, Chryst-Stangl M, Wu G, Shalaby M, El Desoky S, Middleton CC, Huggins K, Sood A, Ochoa A, Malone AF, Vancini R, Miller SE, Hall G, Kim SY, Howell DN, Kari JA, Gbadegesin R
JCI insight 2022 Jan 25;7(2)

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Role of Sleep Restriction in Daily Rhythms of Expression of Hypothalamic Core Clock Genes in Mice.

Li W, Wang Z, Cao J, Dong Y, Chen Y
Current issues in molecular biology 2022 Jan 25;44(2):609-625

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Structure and transport mechanism of the human cholesterol transporter ABCG1.

Xu D, Li Y, Yang F, Sun CR, Pan J, Wang L, Chen ZP, Fang SC, Yao X, Hou WT, Zhou CZ, Chen Y
Cell reports 2022 Jan 25;38(4):110298

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The Mitochondrial PHB2/OMA1/DELE1 Pathway Cooperates with Endoplasmic Reticulum Stress to Facilitate the Response to Chemotherapeutics in Ovarian Cancer.

Cheng M, Yu H, Kong Q, Wang B, Shen L, Dong D, Sun L
International journal of molecular sciences 2022 Jan 25;23(3)

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Integrative bioinformatics and experimental analysis revealed TEAD as novel prognostic target for hepatocellular carcinoma and its roles in ferroptosis regulation.

Ren X, Wang X, Yan Y, Chen X, Cai Y, Liang Q, Peng B, Xu Z, He Q, Kang F, Li J, Zhang W, Hong Q, Peng J, Xiao M
Aging 2022 Jan 25;14(2):961-974

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Modular assembly of the principal microtubule nucleator γ-TuRC.

Würtz M, Zupa E, Atorino ES, Neuner A, Böhler A, Rahadian AS, Vermeulen BJA, Tonon G, Eustermann S, Schiebel E, Pfeffer S
Nature communications 2022 Jan 25;13(1):473

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SARS-CoV-2 NSP5 and N protein counteract the RIG-I signaling pathway by suppressing the formation of stress granules.

Zheng Y, Deng J, Han L, Zhuang MW, Xu Y, Zhang J, Nan ML, Xiao Y, Zhan P, Liu X, Gao C, Wang PH
Signal transduction and targeted therapy 2022 Jan 24;7(1):22

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Sodium hydrosulfide reverses β(2)-microglobulin-induced depressive-like behaviors of male Sprague-Dawley rats: Involving improvement of synaptic plasticity and enhancement of Warburg effect in hippocampus.

Yang SQ, Tang YY, Zeng D, Tian Q, Wei HJ, Wang CY, Zhang P, Chen YJ, Zou W, Tang XQ
Behavioural brain research 2022 Jan 24;417:113562

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Salubrinal protects against inflammatory response in macrophage and attenuates psoriasiform skin inflammation by antagonizing NF-κB signaling pathway.

Shangguan Y, Chen Y, Ma Y, Zhao Y, He Y, Li W
Biochemical and biophysical research communications 2022 Jan 22;589:63-70

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4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone provokes progression from chronic pancreatitis to pancreatic intraepithelial neoplasia.

Chen X, Sheng L, Ma J, Qi D, Li X, Wang Z, Wu Z, Wong L, Huang JH, Wu E, Ma Q, Zhang D
iScience 2022 Jan 21;25(1):103647

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Pyk2 suppresses contextual fear memory in an autophosphorylation-independent manner.

Zheng J, Suo L, Zhou Y, Jia L, Li J, Kuang Y, Cui D, Zhang X, Wu Q
Journal of molecular cell biology 2022 Jan 21;13(11):808-821

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Benzaldehyde Attenuates the Fifth Stage Larval Excretory-Secretory Product of Angiostrongylus cantonensis-Induced Injury in Mouse Astrocytes via Regulation of Endoplasmic Reticulum Stress and Oxidative Stress.

Chen KY, Chen YJ, Cheng CJ, Jhan KY, Wang LC
Biomolecules 2022 Jan 21;12(2)

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Epimedium protects against dyszoospermia in mice with Pex3 knockout by exerting antioxidant effects and regulating the expression level of P16.

Zhao H, Zhao T, Yang J, Huang Q, Wu H, Pan Y, Wang H, Qian Y
Cell death & disease 2022 Jan 20;13(1):69

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PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells by phosphorylating PRAS40.

Zhang T, Wang Y, Yu H, Zhang T, Guo L, Xu J, Wei X, Wang N, Wu Y, Wang X, Huang L
Cell death & disease 2022 Jan 20;13(1):68

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Extracellular vesicles from adipose-derived stem cells promote microglia M2 polarization and neurological recovery in a mouse model of transient middle cerebral artery occlusion.

Hu X, Pan J, Li Y, Jiang Y, Zheng H, Shi R, Zhang Q, Liu C, Tian H, Zhang Z, Tang Y, Yang GY, Wang Y
Stem cell research & therapy 2022 Jan 20;13(1):21

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Pulsed electromagnetic field alleviates synovitis and inhibits the NLRP3/Caspase-1/GSDMD signaling pathway in osteoarthritis rats.

Liu J, Huang X, Zhou J, Li L, Xiao H, Qu M, Sun Z
Electromagnetic biology and medicine 2022 Jan 2;41(1):101-107

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4,5-Dimethoxycanthin-6-one is a novel LSD1 inhibitor that inhibits proliferation of glioblastoma cells and induces apoptosis and pyroptosis.

Li W, Huang BS, Xiong YY, Yang LJ, Wu LX
Cancer cell international 2022 Jan 18;22(1):32

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PDGF-D-PDGFRβ signaling enhances IL-15-mediated human natural killer cell survival.

Ma S, Tang T, Wu X, Mansour AG, Lu T, Zhang J, Wang LS, Caligiuri MA, Yu J
Proceedings of the National Academy of Sciences of the United States of America 2022 Jan 18;119(3)

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Genome-wide CRISPR/Cas9 library screen identifies PCMT1 as a critical driver of ovarian cancer metastasis.

Zhang J, Li Y, Liu H, Zhang J, Wang J, Xia J, Zhang Y, Yu X, Ma J, Huang M, Wang J, Wang L, Li Q, Cui R, Yang W, Xu Y, Feng W
Journal of experimental & clinical cancer research : CR 2022 Jan 15;41(1):24

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The amino acids of Autographa californica multiple nucleopolyhedrovirus P48 critical for the association with Ac93 are important for the nuclear egress of nucleocapsids and efficient formation of intranuclear microvesicles.

Wang Y, He J, Mo M, Cai Q, Wu W, Yuan M, Yang K
Virus research 2022 Jan 15;308:198644

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Ellagic acid ameliorates paraquat-induced liver injury associated with improved gut microbial profile.

Qi M, Wang N, Xiao Y, Deng Y, Zha A, Tan B, Wang J, Yin Y, Liao P
Environmental pollution (Barking, Essex : 1987) 2022 Jan 15;293:118572

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A novel role for PRL in regulating epithelial cell density by inducing apoptosis at confluence.

Lohani S, Funato Y, Akieda Y, Mizutani K, Takai Y, Ishitani T, Miki H
Journal of cell science 2022 Jan 15;135(2)

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Identification of G protein-coupled receptor 55 (GPR55) as a target of curcumin.

Harada N, Okuyama M, Teraoka Y, Arahori Y, Shinmori Y, Horiuchi H, Luis PB, Joseph AI, Kitakaze T, Matsumura S, Hira T, Yamamoto N, Iuni T, Goshima N, Schneider C, Inui H, Yamaji R
NPJ science of food 2022 Jan 14;6(1):4

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The PERK/PKR-eIF2α Pathway Negatively Regulates Porcine Hemagglutinating Encephalomyelitis Virus Replication by Attenuating Global Protein Translation and Facilitating Stress Granule Formation.

Shi J, Li Z, Xu R, Zhang J, Zhou Q, Gao R, Lu H, Lan Y, Zhao K, He H, Gao F, He W
Journal of virology 2022 Jan 12;96(1):e0169521

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Extracellular vesicles derived from glioblastoma promote proliferation and migration of neural progenitor cells via PI3K-Akt pathway.

Pan J, Sheng S, Ye L, Xu X, Ma Y, Feng X, Qiu L, Fan Z, Wang Y, Xia X, Zheng JC
Cell communication and signaling : CCS 2022 Jan 12;20(1):7

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The Effects of Intraoperative Hypothermia on Postoperative Cognitive Function in the Rat Hippocampus and Its Possible Mechanisms.

Xu G, Li T, Huang Y
Brain sciences 2022 Jan 12;12(1)

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Selenium Induces Pancreatic Cancer Cell Death Alone and in Combination with Gemcitabine.

Wooten DJ, Sinha I, Sinha R
Biomedicines 2022 Jan 11;10(1)

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Anti-tumor effect of Yanggan Huayu granule by inducing AKT-mediated apoptosis in hepatocellular carcinoma.

Shen Y, Yang F, Peng H, Zhang G, Zhu F, Xu H, Shi L
Journal of ethnopharmacology 2022 Jan 10;282:114601

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Tanshinone IIA alleviates NLRP3 inflammasome-mediated pyroptosis in Mycobacterium tuberculosis-(H37Ra-) infected macrophages by inhibiting endoplasmic reticulum stress.

Li Y, Fu Y, Sun J, Shen J, Liu F, Ning B, Lu Z, Wei L, Jiang X
Journal of ethnopharmacology 2022 Jan 10;282:114595

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Xiaoyao powder improves endometrial receptivity via VEGFR-2-mediated angiogenesis through the activation of the JNK and P38 signaling pathways.

He M, Li L, Wei X, Geng D, Jiang H, Xiangxiang G, Zhang Y, Du H
Journal of ethnopharmacology 2022 Jan 10;282:114580

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Lactobacillus rhamnosus Ameliorates Multi-Drug-Resistant Bacillus cereus-Induced Cell Damage through Inhibition of NLRP3 Inflammasomes and Apoptosis in Bovine Endometritis.

Liu N, Wang X, Shan Q, Xu L, Li Y, Chu B, Yang L, Wang J, Zhu Y
Microorganisms 2022 Jan 10;10(1)

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Overexpression of Lin28a induces a primary ovarian insufficiency phenotype via facilitation of primordial follicle activation in mice.

Chen J, Liu W, Lee KF, Liu K, Wong BPC, Shu-Biu Yeung W
Molecular and cellular endocrinology 2022 Jan 1;539:111460

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Ligature induced periodontitis in rats causes gut dysbiosis leading to hepatic injury through SCD1/AMPK signalling pathway.

Xing T, Liu Y, Cheng H, Bai M, Chen J, Ji H, He M, Chen K
Life sciences 2022 Jan 1;288:120162

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Role of notch signaling pathway in Muc5ac secretion induced by atmospheric PM(2.5) in rats.

Liu Y, Zhou L, Wu H, Wang Y, Danzengluobu, Zhang B
Ecotoxicology and environmental safety 2022 Jan 1;229:113052

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PTP70-2, a novel polysaccharide from Polygala tenuifolia, prevents neuroinflammation and protects neurons by suppressing the TLR4-mediated MyD88/NF-κB signaling pathway.

Chen H, Zhong J, Li J, Zeng Z, Yu Q, Yan C
International journal of biological macromolecules 2022 Jan 1;194:546-555

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Agrimoniin sensitizes pancreatic cancer to apoptosis through ROS-mediated energy metabolism dysfunction.

Zhu X, Zhang Y, Wang Y, Zhang H, Wang X, Tang H, Huang H, Zhou Z, Chen B, Sun L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153807

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Sleeve gastrectomy suppresses hepatic de novo cholesterogenesis and improves hepatic cholesterol accumulation in obese rats with type 2 diabetes mellitus.

Chen F, Liu B
Nutrition (Burbank, Los Angeles County, Calif.) 2022 Feb;94:111531

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Impaired Sphingosine-1-Phosphate Synthesis Induces Preeclampsia by Deactivating Trophoblastic YAP (Yes-Associated Protein) Through S1PR2 (Sphingosine-1-Phosphate Receptor-2)-Induced Actin Polymerizations.

Liao J, Zheng Y, Hu M, Xu P, Lin L, Liu X, Wu Y, Huang B, Ye X, Li S, Duan R, Fu H, Huang J, Wen L, Fu Y, Kilby MD, Kenny LC, Baker PN, Qi H, Tong C
Hypertension (Dallas, Tex. : 1979) 2022 Feb;79(2):399-412

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Transgelin-2 interacts with CD44 to regulate Notch1 signaling pathway and participates in colorectal cancer proliferation and migration.

Ding R, Li G, Yao Y, Zhang L, Zhang X, Li J, Shen T, Gao Y, Wu T, Kong S, Huang M, Li Y
Journal of physiology and biochemistry 2022 Feb;78(1):99-108

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NPC1-regulated dynamic of clathrin-coated pits is essential for viral entry.

Li G, Su B, Fu P, Bai Y, Ding G, Li D, Wang J, Yang G, Chu B
Science China. Life sciences 2022 Feb;65(2):341-361

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Notch activation suppresses endothelial cell migration and sprouting via miR-223-3p targeting Fbxw7.

Wang R, Yang Z, Liang L, Feng X, Che B, Zhang X, Zheng Q, Yan X, Han H
In vitro cellular & developmental biology. Animal 2022 Feb;58(2):124-135

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The IFN-inducible GTPase IRGB10 regulates viral replication and inflammasome activation during influenza A virus infection in mice.

Christgen S, Place DE, Zheng M, Briard B, Yamamoto M, Kanneganti TD
European journal of immunology 2022 Feb;52(2):285-296

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Benchmarking a highly selective USP30 inhibitor for enhancement of mitophagy and pexophagy.

Rusilowicz-Jones EV, Barone FG, Lopes FM, Stephen E, Mortiboys H, Urbé S, Clague MJ
Life science alliance 2022 Feb;5(2)

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Induction of estrogen receptor β-mediated autophagy sensitizes breast cancer cells to TAD1822-7, a novel biphenyl urea taspine derivative.

Su Q, Wu Q, Chen K, Wang J, Sarwar A, Zhang Y
Molecular biology reports 2022 Feb;49(2):1223-1232

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PDCD4 Simultaneously Promotes Microglia Activation via PDCD4-MAPK-NF-κB Positive Loop and Facilitates Neuron Apoptosis During Neuroinflammation.

Chen Q, Lu H, Duan C, Zhu X, Zhang Y, Li M, Zhang D
Inflammation 2022 Feb;45(1):234-252

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Methylene blue prevents osteoarthritis progression and relieves pain in rats via upregulation of Nrf2/PRDX1.

Li JW, Wang RL, Xu J, Sun KY, Jiang HM, Sun ZY, Lv ZY, Xu XQ, Wu R, Guo H, Jiang Q, Shi DQ
Acta pharmacologica Sinica 2022 Feb;43(2):417-428

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An IgD-Fc-Ig fusion protein restrains the activation of T and B cells by inhibiting IgD-IgDR-Lck signaling in rheumatoid arthritis.

Hu XX, Zhang AJ, Pan WW, Xin QL, Chen JY, Zhang LL, Chang Y, Wu YJ, Wei W
Acta pharmacologica Sinica 2022 Feb;43(2):387-400

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Ginsenoside Rb1 alleviates diabetic kidney podocyte injury by inhibiting aldose reductase activity.

He JY, Hong Q, Chen BX, Cui SY, Liu R, Cai GY, Guo J, Chen XM
Acta pharmacologica Sinica 2022 Feb;43(2):342-353

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Malic enzyme 2 maintains protein stability of mutant p53 through 2-hydroxyglutarate.

Zhao M, Yao P, Mao Y, Wu J, Wang W, Geng C, Cheng J, Du W, Jiang P
Nature metabolism 2022 Feb;4(2):225-238

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Establishment of a pseudovirus neutralization assay based on SARS-CoV-2 S protein incorporated into lentiviral particles.

Wang S, Liu L, Wang C, Wang Z, Duan X, Chen G, Zhou H, Shao H
Biosafety and health 2022 Feb;4(1):38-44

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Estrogen receptor beta increases clear cell renal cell carcinoma stem cell phenotype via altering the circPHACTR4/miR-34b-5p/c-Myc signaling.

Wang Y, Yang Z, Gu J, Zhang Y, Wang X, Teng Z, Wang D, Gao L, Li W, Yeh S, Han Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Feb;36(2):e22163

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Spindle pole body component 24 homolog potentiates tumor progression via regulation of SRY-box transcription factor 2 in clear cell renal cell carcinoma.

Sun C, Wei J, Long Z, Zhao W, Huangfu Q, Xie Q, Wang B, Wen J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Feb;36(2):e22086

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Activation of PGC-1α via isoliquiritigenin-induced downregulation of miR-138-5p alleviates nonalcoholic fatty liver disease.

Wang L, Wang X, Kong L, Li Y, Huang K, Wu J, Wang C, Sun H, Sun P, Gu J, Luo H, Liu K, Meng Q
Phytotherapy research : PTR 2022 Feb;36(2):899-913

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Exogenous melatonin prevents type 1 diabetes mellitus-induced bone loss, probably by inhibiting senescence.

Gong Z, Da W, Tian Y, Zhao R, Qiu S, Wu Q, Wen K, Shen L, Zhou R, Tao L, Zhu Y
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2022 Feb;33(2):453-466

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Neuroglobin expression and function in the temporal cortex of bilirubin encephalopathy rats.

Hu JH, Fan P, Zhang LR, Chen CY, Xu J, Huang J, Lu WT, Zhu SJ, Qiu GP, Xu SY, Ran JH, Gan SW
Anatomical record (Hoboken, N.J. : 2007) 2022 Feb;305(2):254-264

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Cryo-EM structure of mouse TRPML2 in lipid nanodiscs.

Song X, Li J, Tian M, Zhu H, Hu X, Zhang Y, Cao Y, Ye H, McCormick PJ, Zeng B, Fu Y, Duan J, Zhang J
The Journal of biological chemistry 2022 Feb;298(2):101487

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Differential expression of long non-coding RNAs in the hippocampus of mice exposed to PM(2.5) in Dalian, China.

Li J, Zhang L, Wang J, Jia R, Zhang X, Li X, Fu Y, Song L
Environmental science and pollution research international 2022 Feb;29(8):12136-12146

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G protein-coupled receptor 17 restricts rabies virus replication via BAK-mediated apoptosis.

Liu W, Yang Y, Zeng Z, Tian Y, Wu Q, Zhou M, Fu ZF, Zhao L
Veterinary microbiology 2022 Feb;265:109326

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Cinnamic Aldehyde, the main monomer component of Cinnamon, exhibits anti-inflammatory property in OA synovial fibroblasts via TLR4/MyD88 pathway.

Chen P, Zhou J, Ruan A, Zeng L, Liu J, Wang Q
Journal of cellular and molecular medicine 2022 Feb;26(3):913-924

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Cancer-cell-derived GABA promotes β-catenin-mediated tumour growth and immunosuppression.

Huang D, Wang Y, Thompson JW, Yin T, Alexander PB, Qin D, Mudgal P, Wu H, Liang Y, Tan L, Pan C, Yuan L, Wan Y, Li QJ, Wang XF
Nature cell biology 2022 Feb;24(2):230-241

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The volume-regulated anion channel LRRC8C suppresses T cell function by regulating cyclic dinucleotide transport and STING-p53 signaling.

Concepcion AR, Wagner LE 2nd, Zhu J, Tao AY, Yang J, Khodadadi-Jamayran A, Wang YH, Liu M, Rose RE, Jones DR, Coetzee WA, Yule DI, Feske S
Nature immunology 2022 Feb;23(2):287-302

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Mesenchymal stem cell-derived exosome mediated long non-coding RNA KLF3-AS1 represses autophagy and apoptosis of chondrocytes in osteoarthritis.

Wen C, Lin L, Zou R, Lin F, Liu Y
Cell cycle (Georgetown, Tex.) 2022 Feb;21(3):289-303

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Role of TGF-β1 in Fluoride-Treated Osteoblasts at Different Stages.

Jiang N, Xu W, Zhang Z, Jin H, Yang Y, Zhang J, Xu H
Biological trace element research 2022 Feb;200(2):740-748

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Zinc Protects against Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in TM3 Leydig Cells.

Xiong Y, Li J, He S
Biological trace element research 2022 Feb;200(2):728-739

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Assessing Mitochondrial DNA Release into the Cytosol and Subsequent Activation of Innate Immune-related Pathways in Mammalian Cells.

Bryant JD, Lei Y, VanPortfliet JJ, Winters AD, West AP
Current protocols 2022 Feb;2(2):e372

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Survivin suppression heightens BZML-induced mitotic catastrophe to overcome multidrug resistance by removing therapy-induced senescent A549/Taxol cells.

Bai Z, Zhou Y, Ye X, Li Y, Peng Y, Guan Q, Zhang W, Ma L
Biochimica et biophysica acta. Molecular cell research 2022 Feb;1869(2):119174

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MxB inhibits long interspersed element type 1 retrotransposition.

Huang Y, Xu F, Mei S, Liu X, Zhao F, Wei L, Fan Z, Hu Y, Wang L, Ai B, Cen S, Liang C, Guo F
PLoS genetics 2022 Feb;18(2):e1010034

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miRNA-338-3p inhibits glioma cell proliferation and progression by targeting MYT1L.

Yu Z, Liu Y, Li Y, Zhang J, Peng J, Gong J, Xia Y, Wang L
Brain research bulletin 2022 Feb;179:1-12

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The histone deacetylase inhibitor belinostat ameliorates experimental autoimmune encephalomyelitis in mice by inhibiting TLR2/MyD88 and HDAC3/ NF-κB p65-mediated neuroinflammation.

Shen Y, Yang R, Zhao J, Chen M, Chen S, Ji B, Chen H, Liu D, Li L, Du G
Pharmacological research 2022 Feb;176:105969

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Anti-Inflammatory and Anti-Oxidant Activity of Ultra-Short Wave Diathermy on LPS-Induced Rat Lung Injury.

Wu Q, Qu M, Zhong P, Zeng Y, Wang J, Zhang Q, Wang T, Liu D, Yang L, Zhou J, Wang T
Bulletin of experimental biology and medicine 2022 Feb;172(4):423-429

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Hydrogen-rich water ameliorates neuropathological impairments in a mouse model of Alzheimer's disease through reducing neuroinflammation and modulating intestinal microbiota.

Lin YT, Shi QQ, Zhang L, Yue CP, He ZJ, Li XX, He QJ, Liu Q, Du XB
Neural regeneration research 2022 Feb;17(2):409-417

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OLFM4 depletion sensitizes gallbladder cancer cells to cisplatin through the ARL6IP1/caspase-3 axis.

Lin Z, Yang S, Zhou Y, Hou Z, Li L, Meng M, Ge C, Zeng B, Lai J, Gao H, Zhao Y, Xie Y, He S, Tang W, Li R, Tan J, Wang W
Translational oncology 2022 Feb;16:101331

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IL-22 Downregulates Peptidylarginine Deiminase-1 in Human Keratinocytes: Adding Another Piece to the IL-22 Puzzle in Epidermal Barrier Formation.

Padhi A, Srivastava A, Ramesh A, Ehrström M, Simon M, Sonkoly E, Eidsmo L, Bergman P, Lysell J
The Journal of investigative dermatology 2022 Feb;142(2):333-342.e6

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Sodium butyrate alleviates pre-eclampsia in pregnant rats by improving the gut microbiota and short-chain fatty acid metabolites production.

Yong W, Zhao Y, Jiang X, Li P
Journal of applied microbiology 2022 Feb;132(2):1370-1383

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Pleckstrin homology-like domain family A, member 3, a miR-19a-3p-regulated gene, suppresses tumor growth in osteosarcoma by downregulating the Akt pathway.

Wang P, Huang Y, Xia X, Han J, Zhang L, Zhao W
Bioengineered 2022 Feb;13(2):3993-4009

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Salvianolic acid B alleviates diabetic endothelial and mitochondrial dysfunction by down-regulating apoptosis and mitophagy of endothelial cells.

Xiang J, Zhang C, Di T, Chen L, Zhao W, Wei L, Zhou S, Wu X, Wang G, Zhang Y
Bioengineered 2022 Feb;13(2):3486-3502

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Vibrio harveyi infections induce production of proinflammatory cytokines in murine peritoneal macrophages via activation of p38 MAPK and NF-κB pathways, but reversed by PI3K/AKT pathways.

Yu G, Yu H, Yang Q, Wang J, Fan H, Liu G, Wang L, Bello BK, Zhao P, Zhang H, Dong J
Developmental and comparative immunology 2022 Feb;127:104292

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Persistent high glucose induced EPB41L4A-AS1 inhibits glucose uptake via GCN5 mediating crotonylation and acetylation of histones and non-histones.

Liao W, Xu N, Zhang H, Liao W, Wang Y, Wang S, Zhang S, Jiang Y, Xie W, Zhang Y
Clinical and translational medicine 2022 Feb;12(2):e699

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Paclitaxel-based supramolecular hydrogel loaded with mifepristone for the inhibition of breast cancer metastasis.

Zhao CC, Zhang CG, Sun X, Guo Q, Liu J, Liu Y, Hao YN, Feng G, Yang L, Liu H, Liu J
Cancer science 2022 Feb;113(2):733-743

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One-Step Synthesis of Multifunctional Chitosan Hydrogel for Full-Thickness Wound Closure and Healing.

Guo S, Yao M, Zhang D, He Y, Chang R, Ren Y, Guan F
Advanced healthcare materials 2022 Feb;11(4):e2101808

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Sodium houttuynia alleviates airway inflammation in asthmatic mice by regulating FoxP3/RORγT expression and reversing Treg/Th17 cell imbalance.

Wang C, Huang CF, Li M
International immunopharmacology 2022 Feb;103:108487

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MiR-29b-1-5p regulates the proliferation and differentiation of chicken primary myoblasts and analysis of its effective targets.

Li Y, Zhai B, Yuan P, Fan S, Jin W, Li W, Sun G, Tian Y, Liu X, Kang X, Li G
Poultry science 2022 Feb;101(2):101557

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ATF6-Mediated Unfolded Protein Response Facilitates Adeno-associated Virus 2 (AAV2) Transduction by Releasing the Suppression of the AAV Receptor on Endoplasmic Reticulum Stress.

Cui M, Zhao Q, Wang J, Si Y, Cheng S, Ding W
Journal of virology 2022 Feb 9;96(3):e0110321

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The spliceosome component Usp39 controls B cell development by regulating immunoglobulin gene rearrangement.

Ruan GX, Li Y, Chen W, Huang H, Zhang R, Chen C, Lam KP, Xu S, Ou X
Cell reports 2022 Feb 8;38(6):110338

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Staphylococcus aureus mediates pyroptosis in bovine mammary epithelial cell via activation of NLRP3 inflammasome.

Wang X, Liu M, Geng N, Du Y, Li Z, Gao X, Han B, Liu J, Liu Y
Veterinary research 2022 Feb 5;53(1):10

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AQP4 Attenuated TRAF6/NFκB Activation in Acrylamide-Induced Neurotoxicity.

Hung CY, Chang CH, Lin TJ, Yi HH, Tsai NZ, Chen YR, Chen YT
Molecules (Basel, Switzerland) 2022 Feb 4;27(3)

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N-myc downstream regulated gene 1 suppresses osteoblast differentiation through inactivating Wnt/β-catenin signaling.

Shi X, Cen Y, Shan L, Tian L, Zhu E, Yuan H, Li X, Liu Y, Wang B
Stem cell research & therapy 2022 Feb 4;13(1):53

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Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance.

Chen Y, Wu X, Zhang J, Pan G, Wang X, Guo X, Wang J, Cui X, Gao H, Cheng M, Yang J, Zhang C, Jiang F
EMBO reports 2022 Feb 3;23(3):e53373

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Heterozygous FMN2 missense variant found in a family case of premature ovarian insufficiency.

Li J, Peng T, Wang L, Long P, Quan R, Tan H, Zeng M, Wu X, Yang J, Xiao H, Shi X
Journal of ovarian research 2022 Feb 28;15(1):31

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MYSM1 induces apoptosis and sensitizes TNBC cells to cisplatin via RSK3-phospho-BAD pathway.

Guan X, Meng X, Zhu K, Kai J, Liu Y, Ma Q, Tong Y, Zheng H, Xie S, Ma X, Wang Y, Lu R, Guo L
Cell death discovery 2022 Feb 26;8(1):84

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Changes of flavin-containing monooxygenases and trimethylamine-N-oxide may be involved in the promotion of non-alcoholic fatty liver disease by intestinal microbiota metabolite trimethylamine.

Shi C, Pei M, Wang Y, Chen Q, Cao P, Zhang L, Guo J, Deng W, Wang L, Li X, Gong Z
Biochemical and biophysical research communications 2022 Feb 26;594:1-7

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Norepinephrine promotes glioma cell migration through up-regulating the expression of Twist1.

Wang X, Wang Y, Xie F, Song ZT, Zhang ZQ, Zhao Y, Wang SD, Hu H, Zhang YS, Qian LJ
BMC cancer 2022 Feb 26;22(1):213

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Circular RNA circSHPRH inhibits the malignant behaviors of bladder cancer by regulating the miR-942/BARX2 pathway.

Zuo L, Zhu Y, Han J, Liu H
Aging 2022 Feb 24;14(4):1891-1909

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Comprehensive Analysis of Protein Acetylation and Glucose Metabolism in Mouse Brains Infected with Rabies Virus.

Pei J, Yuan Y, Tian D, Huang F, Zhang C, Wang C, Zhou M, Chen H, Fu Z, Zhao L
Journal of virology 2022 Feb 23;96(4):e0194221

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Neuroprotection of chicoric acid in a mouse model of Parkinson's disease involves gut microbiota and TLR4 signaling pathway.

Wang N, Feng BN, Hu B, Cheng YL, Guo YH, Qian H
Food & function 2022 Feb 21;13(4):2019-2032

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Employing CRISPR-Cas9 to Generate CD133 Synthetic Lethal Melanoma Stem Cells.

Simbulan-Rosenthal CM, Haribabu Y, Vakili S, Kuo LW, Clark H, Dougherty R, Alobaidi R, Carney B, Sykora P, Rosenthal DS
International journal of molecular sciences 2022 Feb 20;23(4)

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The deubiquitinating enzyme USP20 regulates the stability of the MCL1 protein.

Feng J, Liu P, Li X, Zhang D, Lin H, Hou Z, Guo C, Niu Y, Dai B, Wang O, Qi M, Wang H, Zhou H
Biochemical and biophysical research communications 2022 Feb 19;593:122-128

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PINK1-parkin-mediated neuronal mitophagy deficiency in prion disease.

Li J, Lai M, Zhang X, Li Z, Yang D, Zhao M, Wang D, Sun Z, Ehsan S, Li W, Gao H, Zhao D, Yang L
Cell death & disease 2022 Feb 18;13(2):162

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Overexpressed mitogen-and stress-activated protein kinase 1 promotes the resistance of cytarabine in acute myeloid leukemia through brahma related gene 1-mediated upregulation of heme oxygenase-1.

Zhang S, Pan C, Shang Q, Wang W, Hu T, Liu P, Chen S, Wang J, Fang Q
European journal of pharmacology 2022 Feb 15;917:174722

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Synthesis and biological evaluation of aminobenzamides containing purine moiety as class I histone deacetylases inhibitors.

Mao PT, He WB, Mai X, Feng LH, Li N, Liao YJ, Zhu CS, Li J, Chen T, Liu SH, Zhang QM, He L
Bioorganic & medicinal chemistry 2022 Feb 15;56:116599

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Asprosin induces vascular endothelial-to-mesenchymal transition in diabetic lower extremity peripheral artery disease.

You M, Liu Y, Wang B, Li L, Zhang H, He H, Zhou Q, Cao T, Wang L, Zhao Z, Zhu Z, Gao P, Yan Z
Cardiovascular diabetology 2022 Feb 15;21(1):25

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Themis is indispensable for IL-2 and IL-15 signaling in T cells.

Liu Y, Cong Y, Niu Y, Yuan Y, Tan F, Lai Q, Hu Y, Hou B, Li J, Lin C, Zheng H, Dong J, Tang J, Chen Q, Brzostek J, Zhang X, Chen XL, Wang HR, Gascoigne NRJ, Xu B, Lin SH, Fu G
Science signaling 2022 Feb 15;15(721):eabi9983

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Novel stress granule-like structures are induced via a paracrine mechanism during viral infection.

Iadevaia V, Burke JM, Eke L, Moller-Levet C, Parker R, Locker N
Journal of cell science 2022 Feb 15;135(4)

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Programmed death-ligand 1 signaling and expression are reversible by lycopene via PI3K/AKT and Raf/MEK/ERK pathways in tongue squamous cell carcinoma.

Peng M, Fan S, Li J, Zhou X, Liao Q, Tang F, Liu W
Genes & nutrition 2022 Feb 14;17(1):3

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Chicoric Acid Prevents Neuroinflammation and Neurodegeneration in a Mouse Parkinson's Disease Model: Immune Response and Transcriptome Profile of the Spleen and Colon.

Wang N, Li R, Feng B, Cheng Y, Guo Y, Qian H
International journal of molecular sciences 2022 Feb 12;23(4)

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ZHX2 inhibits thyroid cancer metastasis through transcriptional inhibition of S100A14.

Zhang Y, Sun M, Gao L, Liang X, Ma C, Lu J, Yue X
Cancer cell international 2022 Feb 12;22(1):76

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A Second Near-Infrared Ru(II) Polypyridyl Complex for Synergistic Chemo-Photothermal Therapy.

Liu Y, Li Q, Gu M, Lu D, Xiong X, Zhang Z, Pan Y, Liao Y, Ding Q, Gong W, Chen DS, Guan M, Wu J, Tian Z, Deng H, Gu L, Hong X, Xiao Y
Journal of medicinal chemistry 2022 Feb 10;65(3):2225-2237

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Structural Optimization and Structure-Activity Relationship Studies of 6,6-Dimethyl-4-(phenylamino)-6H-pyrimido[5,4-b][1,4]oxazin-7(8H)-one Derivatives as A New Class of Potent Inhibitors of Pan-Trk and Their Drug-Resistant Mutants.

Pan S, Zhang L, Luo X, Nan J, Yang W, Bin H, Li Y, Huang Q, Wang T, Pan Z, Mu B, Wang F, Tian C, Liu Y, Li L, Yang S
Journal of medicinal chemistry 2022 Feb 10;65(3):2035-2058

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Discovery of 3,4-Dihydrobenzo[f][1,4]oxazepin-5(2H)-one Derivatives as a New Class of Selective TNIK Inhibitors and Evaluation of Their Anti-Colorectal Cancer Effects.

Li Y, Zhang L, Yang R, Qiao Z, Wu M, Huang C, Tian C, Luo X, Yang W, Zhang Y, Li L, Yang S
Journal of medicinal chemistry 2022 Feb 10;65(3):1786-1807

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Anti-proliferation and anti-inflammation effects of corilagin in rheumatoid arthritis by downregulating NF-κB and MAPK signaling pathways.

Shen Y, Teng L, Qu Y, Liu J, Zhu X, Chen S, Yang L, Huang Y, Song Q, Fu Q
Journal of ethnopharmacology 2022 Feb 10;284:114791

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Physiological and transcriptomic analyses reveal the toxicological mechanism and risk assessment of environmentally-relevant waterborne tetracycline exposure on the gills of tilapia (Oreochromis niloticus).

Xu YC, Liu GH, Xu YH, Zhao T, Zheng H, Tan XY
The Science of the total environment 2022 Feb 1;806(Pt 3):151290

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Berberine inhibits gastric cancer development and progression by regulating the JAK2/STAT3 pathway and downregulating IL-6.

Xu M, Ren L, Fan J, Huang L, Zhou L, Li X, Ye X
Life sciences 2022 Feb 1;290:120266

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Silk fibroin nanofibrous scaffolds incorporated with microRNA-222 loaded chitosan nanoparticles for enhanced neuronal differentiation of neural stem cells.

Li Z, Meng Z, Zhao Z
Carbohydrate polymers 2022 Feb 1;277:118791

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Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis.

Xu S, Yang X, Chen Q, Liu Z, Chen Y, Yao X, Xiao A, Tian J, Xie L, Zhou M, Hu Z, Zhu F, Xu X, Hou F, Nie J
EBioMedicine 2022 Dec;86:104312

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PRSS2 overexpression relates to poor prognosis and promotes proliferation, migration and invasion in gastric cancer.

Chen Y, Wang B, Zhao Z, Li M, Wang F
Tissue & cell 2022 Dec;79:101949

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Integrated bioinformatics analysis and screening of hub genes in polycystic ovary syndrome.

Qiao G, Xing J, Luo X, Zhang C, Yi J
Endocrine 2022 Dec;78(3):615-627

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Epigenetic silencing by the SMC5/6 complex mediates HIV-1 latency.

Irwan ID, Bogerd HP, Cullen BR
Nature microbiology 2022 Dec;7(12):2101-2113

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CircCERS6 Suppresses the Development of Epithelial Ovarian Cancer Through Mediating miR-630/RASSF8.

Li X, Jiang X, Lu J, Lin Y, Jiang L, Li Y, Wan F, Wang C
Biochemical genetics 2022 Dec;60(6):2611-2629

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Yiqi Huoxue Tongluo recipe regulates NR4A1 to improve renal mitochondrial function in unilateral ureteral obstruction (UUO) rats.

He Z, Zhang M, Xu H, Zhou W, Xu C, Wang Z, He M, Wang X
Pharmaceutical biology 2022 Dec;60(1):2308-2318

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Catalpol relieved angiotensin II-induced blood-brain barrier destruction via inhibiting the TLR4 pathway in brain endothelial cells.

Xia Y, Lu YW, Hao RJ, Yu GR
Pharmaceutical biology 2022 Dec;60(1):2210-2218

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Aspirin relieves the calcification of aortic smooth muscle cells by enhancing the heat shock response.

Shen Q, Chen Q, Liu Y, Xue X, Shen X, He Q, Wang G, Han F
Pharmaceutical biology 2022 Dec;60(1):17-24

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Study on the biological mechanism of urolithin a on nasopharyngeal carcinoma in vitro.

Yang Y, Ren ZZ, Wei WJ, He ZL, Deng YL, Wang Z, Fan YC, Zhou J, Jiang LH
Pharmaceutical biology 2022 Dec;60(1):1566-1577

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Louki Zupa decoction attenuates the airway inflammation in acute asthma mice induced by ovalbumin through IL-33/ST2-NF-κB/GSK3β/mTOR signalling pathway.

Huang X, Yu H, Xie C, Zhou YL, Chen MM, Shi HL, Tang WF, Dong JC, Luo QL
Pharmaceutical biology 2022 Dec;60(1):1520-1532

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Structure and biological evaluation of Caenorhabditis elegans CISD-1/mitoNEET, a KLP-17 tail domain homologue, supports attenuation of paraquat-induced oxidative stress through a p38 MAPK-mediated antioxidant defense response.

Boos JR, Jandrain HN, Hagiuda E, Taguchi AT, Hasegawa K, Fedun BL, Taylor SJ, Elad SM, Faber SE, Kumasaka T, Iwasaki T, Geldenhuys WJ
Advances in redox research 2022 Dec;6

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FUS Mutation Causes Disordered Lipid Metabolism in Skeletal Muscle Associated with ALS.

Zhou B, Zheng Y, Li X, Dong H, Yu J, Zou Y, Zhu M, Yu Y, Fang X, Zhou M, Zhang W, Yuan Y, Wang Z, Deng J, Hong D
Molecular neurobiology 2022 Dec;59(12):7265-7277

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circSKIL promotes osteoblastic differentiation of periodontal ligament cells by sponging miR-532-5p to activate Notch signaling.

Zhong X, Wang H
Journal of periodontal research 2022 Dec;57(6):1148-1158

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Knockdown of ZBTB11 impedes R-loop elimination and increases the sensitivity to cisplatin by inhibiting DDX1 transcription in bladder cancer.

Chen L, Liu Z, Tang H, Zhou Z, Chen J, Ma Z, Deng M, Li X, Wu Y, Zheng L, Zhou L, Zheng X, Liu Z
Cell proliferation 2022 Dec;55(12):e13325

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Periostin contributes to the adventitial remodeling of atherosclerosis by activating adventitial fibroblasts.

Wang Z, Li G, Li M, Hu L, Hao Z, Li Q, Sun C
Atherosclerosis plus 2022 Dec;50:57-64

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Dissection of cellular and molecular mechanisms of aristolochic acid-induced hepatotoxicity via single-cell transcriptomics.

Luo P, Chen J, Zhang Q, Xia F, Wang C, Bai Y, Tang H, Liu D, Gu L, Du Q, Xiao W, Yang C, Wang J
Precision clinical medicine 2022 Dec;5(4):pbac023

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PEDF inhibits non‑small cell lung cancer proliferation by suppressing autophagy through downregulation of AMPK‑ULK1 signaling.

Miao H, Hui H, Li H, Lin Y, Li D, Luo M, Jiang B, Zhang Y
Oncology reports 2022 Dec;48(6)

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The LINC00152/miR-205-5p/CXCL11 axis in hepatocellular carcinoma cancer-associated fibroblasts affects cancer cell phenotypes and tumor growth.

Liu G, Yang ZF, Sun J, Sun BY, Zhou PY, Zhou C, Guan RY, Wang ZT, Yi Y, Qiu SJ
Cellular oncology (Dordrecht, Netherlands) 2022 Dec;45(6):1435-1449

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DNASE1L3 inhibits hepatocellular carcinoma by delaying cell cycle progression through CDK2.

Sun J, Wang X, Shen Q, Wang M, Chen S, Zhang X, Huang Y, Zhang Z, Li W, Yuan Y, Huang Z
Cellular oncology (Dordrecht, Netherlands) 2022 Dec;45(6):1187-1202

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CircRNA-001241 mediates sorafenib resistance of hepatocellular carcinoma cells by sponging miR-21-5p and regulating TIMP3 expression.

Yang Q, Wu G
Gastroenterologia y hepatologia 2022 Dec;45(10):742-752

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Yanghe decoction attenuated pain hypersensitivity induced by michigan cancer foundation-7 injection in rats with bone metastases from breast cancer by inhibiting transient receptor potential ankyrin 1.

Hui G, Yang LI, Lei F, Yujie X, Lizhong H, Dan M, Hui Z
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Dec;42(6):948-955

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A homogalacturonan from Lonicera japonica Thunb. disrupts angiogenesis via epidermal growth factor receptor and Delta-like 4 associated signaling.

Liao W, Hu X, Du Z, Wang P, Ding K
Glycoconjugate journal 2022 Dec;39(6):725-735

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Photobiomodulation effects in metalloproteinases expression in zymosan-induced arthritis.

Dos Anjos LMJ, Quirino-Teixeira AC, Hottz ED, da Fonseca AS, Gameiro J, de Paoli F
Lasers in medical science 2022 Dec;37(9):3661-3670

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3-Arylcoumarin inhibits vascular calcification by inhibiting the generation of AGEs and anti-oxidative stress.

Li Y, Pan Y, Wang L, Wang X, Chu H, Li Y, Mu Y, Sun J
Journal of enzyme inhibition and medicinal chemistry 2022 Dec;37(1):2147-2157

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Effects of bicyclol on hepatic sinusoidal obstruction syndrome induced by Gynura segetum.

Yao J, Wu J, Jia S, Shao J, Zhang X, Xu Z, Zhang H, Li H, Yao X
Journal of clinical laboratory analysis 2022 Dec;36(12):e24793

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Flavonoid extract of saffron by-product alleviates hyperuricemia via inhibiting xanthine oxidase and modulating gut microbiota.

Chen N, Wang R, Li H, Wang W, Wang L, Yin X, Yao R, Yang B
Phytotherapy research : PTR 2022 Dec;36(12):4604-4619

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Andrographolide suppresses breast cancer progression by modulating tumor-associated macrophage polarization through the Wnt/β-catenin pathway.

Li L, Yang LL, Yang SL, Wang RQ, Gao H, Lin ZY, Zhao YY, Tang WW, Han R, Wang WJ, Liu P, Hou ZL, Meng MY, Liao LW
Phytotherapy research : PTR 2022 Dec;36(12):4587-4603

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Expression and significance of let-7a and tumor necrosis factor-alpha in placenta of severe preeclampsia.

Zhou T, Wang W, Qi T, Ma S, Lu W
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022 Dec;35(25):7363-7367

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Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia.

Hu CL, Chen BY, Li Z, Yang T, Xu CH, Yang R, Yu PC, Zhao J, Liu T, Liu N, Shan B, Zhang Q, Song J, Fei MY, Zong LJ, Zhang JY, Wu JC, Chen SB, Wang Y, Chang B, Hou D, Liu P, Jiang Y, Li X, Chen X, Deng CH, Ren YY, Wang R, Jin J, Xue K, Zhang Y, Du M, Shi J, Wu LY, Chang CK, Shen S, Chen Z, Chen SJ, Liu X, Sun XJ, Zheng M, Wang L
Cell research 2022 Dec;32(12):1105-1123

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Androgen receptor suppresses β-adrenoceptor-mediated CREB activation and thermogenesis in brown adipose tissue of male mice.

Harada N, Kubo K, Onishi T, Kitakaze T, Goto T, Inui H, Yamaji R
The Journal of biological chemistry 2022 Dec;298(12):102619

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A recombinant scFv antibody-based fusion protein that targets EGFR associated with IMPDH2 downregulation and its drug conjugate show therapeutic efficacy against esophageal cancer.

He S, Zhao C, Tao H, Sheng W, Gao R, Liu X, Zhen Y
Drug delivery 2022 Dec;29(1):1243-1256

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HIV-1 Tat drives the Fabp4/NF-κB feedback loop in microglia to mediate inflammatory response and neuronal apoptosis.

Zhou X, Zhou S, Tao J, Gao Y, Meng G, Cao D, Gao L
Journal of neurovirology 2022 Dec;28(4-6):483-496

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Enhancement of astrocytic gap junctions Connexin43 coupling can improve long-term isoflurane anesthesia-mediated brain network abnormalities and cognitive impairment.

Dong R, Lv P, Han Y, Jiang L, Wang Z, Peng L, Ma Z, Xia T, Zhang B, Gu X
CNS neuroscience & therapeutics 2022 Dec;28(12):2281-2297

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KDM6B cooperates with Tau and regulates synaptic plasticity and cognition via inducing VGLUT1/2.

Wang Y, Khandelwal N, Liu S, Zhou M, Bao L, Wang JE, Kumar A, Xing C, Gibson JR, Wang Y
Molecular psychiatry 2022 Dec;27(12):5213-5226

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c-Myc plays a critical role in the antileukemic activity of the Mcl-1-selective inhibitor AZD5991 in acute myeloid leukemia.

Liu S, Qiao X, Wu S, Gai Y, Su Y, Edwards H, Wang Y, Lin H, Taub JW, Wang G, Ge Y
Apoptosis : an international journal on programmed cell death 2022 Dec;27(11-12):913-928

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FBXL6 depletion restrains clear cell renal cell carcinoma progression.

Yu Y, Yao W, Wang T, Xue W, Meng Y, Cai L, Jian W, Yu Y, Zhang C
Translational oncology 2022 Dec;26:101550

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Hsp90 Inhibitor STA9090 induced VPS35 related extracellular vesicle release and metastasis in hepatocellular carcinoma.

Tan W, Zhang J, Liu L, Liang M, Li J, Deng Z, Zheng Z, Deng Y, Liu C, Li Y, Xie G, Zhang J, Zou F, Chen X
Translational oncology 2022 Dec;26:101502

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miR‑141 impairs mitochondrial function in cardiomyocytes subjected to hypoxia/reoxygenation by targeting Sirt1 and MFN2.

Zhang H, Wang Y, Wu K, Liu R, Wang H, Yao Y, Kvietys P, Rui T
Experimental and therapeutic medicine 2022 Dec;24(6):763

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Network pharmacology and molecular docking analysis on molecular targets and mechanisms of Gastrodia elata Blume in the treatment of ischemic stroke.

Luo Y, Chen P, Yang L, Duan X
Experimental and therapeutic medicine 2022 Dec;24(6):742

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Pseudogene CSPG4P12 affects the biological behavior of non‑small cell lung cancer by Bcl‑2/Bax mitochondrial apoptosis pathway.

Hu W, Wu H, Li A, Zheng X, Zhang W, Tian Q, Zhang X
Experimental and therapeutic medicine 2022 Dec;24(6):734

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NSUN5 promotes progression and predicts poor prognosis in hepatocellular carcinoma.

Zhang XW, Wu LY, Liu HR, Huang Y, Qi Q, Zhong R, Zhu L, Gao CF, Zhou L, Yu J, Wu HG
Oncology letters 2022 Dec;24(6):439

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The Mechano-Ubiquitinome of Articular Cartilage: Differential Ubiquitination and Activation of a Group of ER-Associated DUBs and ER Stress Regulators.

Kaokhum N, Pinto-Fernández A, Wilkinson M, Kessler BM, Ismail HM
Molecular & cellular proteomics : MCP 2022 Dec;21(12):100419

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Efficient reprogramming of human fibroblasts using RNA reprogramming with DAPT and iDOT1L under normoxia conditions.

Morita K, Nakamura A, Machida M, Kawasaki T, Nakanishi R, Ichida J, Iwata T, Umezawa A, Akutsu H
Regenerative therapy 2022 Dec;21:389-397

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Polydopamine-mediated graphene oxide and nanohydroxyapatite-incorporated conductive scaffold with an immunomodulatory ability accelerates periodontal bone regeneration in diabetes.

Li Y, Yang L, Hou Y, Zhang Z, Chen M, Wang M, Liu J, Wang J, Zhao Z, Xie C, Lu X
Bioactive materials 2022 Dec;18:213-227

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Сyclooxygenase-2 Inhibitor Parecoxib Reduces LPS-Induced Activation of BV2 Microglia Cells.

Li X, Zhou JX, Qu YD, Kuang X
Bulletin of experimental biology and medicine 2022 Dec;174(2):210-215

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Oxidative phosphorylation regulates interleukin-10 production in regulatory B cells via the extracellular signal-related kinase pathway.

Zhu Y, Zhang X, Xie S, Bao W, Chen J, Wu Q, Lai X, Liu L, Xiong S, Peng Y
Immunology 2022 Dec;167(4):576-589

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Rifaximin protects against circadian rhythm disruption-induced cognitive impairment through preventing gut barrier damage and neuroinflammation.

Meng D, Yang M, Hu L, Liu T, Zhang H, Sun X, Wang X, Chen Y, Jin Y, Liu R
Journal of neurochemistry 2022 Dec;163(5):406-418

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Targeted lipidomics analysis of lysine 179 acetylation of ACSF2 in rat hepatic stellate cells.

Wang M, Su Y, Hou C, Ren K, Liu X, Zhao S, Wang Y, Liu X
Prostaglandins & other lipid mediators 2022 Dec;163:106671

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Clitoria ternatea blue petal extract protects against obesity, oxidative stress, and inflammation induced by a high-fat, high-fructose diet in C57BL/6 mice.

Wang Y, Liu T, Xie Y, Li N, Liu Y, Wen J, Zhang M, Feng W, Huang J, Guo Y, Kabbas Junior T, Wang D, Granato D
Food research international (Ottawa, Ont.) 2022 Dec;162(Pt A):112008

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Facile discovery of red blood cell deformation and compromised membrane/skeleton assembly in Prader-Willi syndrome.

Yang Y, Li G, Wang Y, Sun Y, Xu C, Wei Z, Zhang S, Gao L, Liu S, Zhao J
Frontiers of medicine 2022 Dec;16(6):946-956

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R158Q and G212S, novel pathogenic compound heterozygous variants in SLC12A3 of Gitelman syndrome.

Li Z, Wu H, Wei S, Liu M, Shi Y, Li M, Wang N, Fang L, Xiang B, Gao L, Xu C, Zhao J
Frontiers of medicine 2022 Dec;16(6):932-945

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Hyaluronic acids mediate the infiltration, migration, and M2 polarization of macrophages: evaluating metabolic molecular phenotypes in gliomas.

Zhang H, Zhang N, Dai Z, Wang Z, Zhang X, Liang X, Zhang L, Feng S, Wu W, Ye W, Zhang J, Luo P, Liu Z, Cheng Q, Liu Z
Molecular oncology 2022 Dec;16(22):3927-3948

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The transcription factor KLF14 attenuates LPS-induced acute lung injury by ameliorating apoptosis of alveolar epithelial cells in mice.

Liu L, Yuan Y, Zhou Y, Yao L, Li J, Chen F
Molecular immunology 2022 Dec;152:67-77

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The mechanism underlying ICAM-1 and E-selectin-mediated hypertriglyceridemic pancreatitis-associated lung injury.

Yu R, Hou C, Peng Y, Zhu X, Shi C, Huang D, Miao Y, Li Q
Molecular immunology 2022 Dec;152:55-66

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RPLP1, an NS4B-interacting protein, enhances production of CSFV through promoting translation of viral genome.

Zhang L, Lin J, Weng M, Wen Y, Zhang Y, Deng W
Virulence 2022 Dec;13(1):370-386

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Regulation of host factor γ-H2AX level and location by enterovirus A71 for viral replication.

Yu J, Zhang W, Huo W, Meng X, Zhong T, Su Y, Liu Y, Liu J, Wang Z, Song F, Zhang S, Li Z, Yu X, Yu X, Hua S
Virulence 2022 Dec;13(1):241-257

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Tetrandrine alleviates inflammation and neuron apoptosis in experimental traumatic brain injury by regulating the IRE1α/JNK/CHOP signal pathway.

Liu H, He S, Li C, Wang J, Zou Q, Liao Y, Chen R
Brain and behavior 2022 Dec;12(12):e2786

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Pathogenic variants in TSC2 might cause premature ovarian insufficiency through activated mTOR induced hyperactivation of primordial follicles.

Xu B, Li Z, Li S, Ke H, Zhang Q, Qin Y, Guo T
Fertility and sterility 2022 Dec;118(6):1139-1149

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Di-2-ethylhexyl phthalate-induced miR-155-5p promoted lipid metabolism via inhibiting cAMP/PKA signaling pathway in human trophoblastic HTR-8/Svneo cells.

Gu X, Liu H, Luo W, Wang X, Wang H, Li L
Reproductive toxicology (Elmsford, N.Y.) 2022 Dec;114:22-31

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Epoxymicheliolide prevents dextran sulfate sodium-induced colitis in mice by inhibiting TAK1-NF-κB pathway and activating Keap1-NRF2 signaling in macrophages.

He J, Liu L, Liu X, Chen H, Liu K, Huang N, Wang Y
International immunopharmacology 2022 Dec;113(Pt A):109404

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Eplerenone inhibits the macrophage-to-myofibroblast transition in rats with UUO-induced type 4 cardiorenal syndrome through the MR/CTGF pathway.

Han Y, Xian Y, Gao X, Qiang P, Hao J, Yang F, Shimosawa T, Chang Y, Xu Q
International immunopharmacology 2022 Dec;113(Pt A):109396

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Nodakenin attenuates cartilage degradation and inflammatory responses in a mice model of knee osteoarthritis by regulating mitochondrial Drp1/ROS/NLRP3 axis.

Yi N, Mi Y, Xu X, Li N, Chen B, Yan K, Tan K, Zhang B, Wang L, Kuang G, Lu M
International immunopharmacology 2022 Dec;113(Pt A):109349

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Blockade of CBX4-mediated β-catenin SUMOylation attenuates airway epithelial barrier dysfunction in asthma.

Liang S, Zhou Z, Zhou Z, Liang J, Lin W, Zhang C, Zhou C, Zhao H, Meng X, Zou F, Yu C, Cai S
International immunopharmacology 2022 Dec;113(Pt A):109333

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Brown adipocytes promote epithelial mesenchymal transition of neuroblastoma cells by inducing PPAR-γ/UCP2 expression.

Ge Z, Shang Y, Wang W, Yang J, Chen SZ
Adipocyte 2022 Dec;11(1):335-345

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Isorhamnetin protects zearalenone-induced damage via the PI3K/Akt signaling pathway in porcine ovarian granulosa cells.

Li X, Chen H, Zhang Z, Duan J, Hua R, Li X, Yang L, Cheng J, Li Q
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Dec;11:381-390

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Systemic gene therapy for methylmalonic acidemia using the novel adeno-associated viral vector 44.9.

Chandler RJ, Di Pasquale G, Sloan JL, McCoy S, Hubbard BT, Kilts TM, Manoli I, Chiorini JA, Venditti CP
Molecular therapy. Methods & clinical development 2022 Dec 8;27:61-72

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Melatonin Maintains Homeostasis and Potentiates the Anti-inflammatory Response in Staphylococcus aureus-Induced Mastitis through microRNA-16b/YAP1.

Chen Z, Wang K, Guo J, Zhou J, Loor JJ, Yang Z, Yang Y
Journal of agricultural and food chemistry 2022 Dec 7;70(48):15255-15270

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GABA regulates IL-1β production in macrophages.

Fu J, Han Z, Wu Z, Xia Y, Yang G, Yin Y, Ren W
Cell reports 2022 Dec 6;41(10):111770

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CIP2A deficiency promotes depression-like behaviors in mice through inhibition of dendritic arborization.

Hu WT, Liuyang ZY, Tian Y, Liang JW, Zhang XL, Zhang HL, Wang G, Huo Y, Shentu YP, Wang JZ, Wang XC, Lu YM, Westermarck J, Man HY, Liu R
EMBO reports 2022 Dec 6;23(12):e54911

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Silencing of lncRNA SNHG17 inhibits the tumorigenesis of epithelial ovarian cancer through regulation of miR-485-5p/AKT1 axis.

Wang W, Yu S, Li W, Hu H, Zou G
Biochemical and biophysical research communications 2022 Dec 31;637:117-126

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LncRNA GAS5 regulates the Wnt/β-catenin pathway through the miR-18a-5p/AXIN2/GSK3β axis to inhibit the proliferation and migration of bladder cancer cells.

Zhang Z, Liu T, Cheng C, Wang J, Wang C, Huang H, Li Y
Carcinogenesis 2022 Dec 31;43(12):1176-1189

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Mechanically activated ion channel Piezo1 contributes to melanoma malignant progression through AKT/mTOR signaling.

Zhang S, Cao S, Gong M, Zhang W, Zhang W, Zhu Z, Wu S, Yue Y, Qian W, Ma Q, Wang S, Wang Z
Cancer biology & therapy 2022 Dec 31;23(1):336-347

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Exosome-transmitted S100A4 induces immunosuppression and non-small cell lung cancer development by activating STAT3.

Wu X, Zhang H, Jiang G, Peng M, Li C, Lu J, Jiang S, Yang X, Jiang Y
Clinical and experimental immunology 2022 Dec 31;210(3):309-320

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Quercetin ameliorates memory impairment by inhibiting abnormal microglial activation in a mouse model of paradoxical sleep deprivation.

Zhang Y, Xie Y, Cheng Z, Xi K, Huang X, Kuang F, Wang W, Liu T, Guo B, Wu S
Biochemical and biophysical research communications 2022 Dec 3;632:10-16

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Geraniol-Mediated Suppression of Endoplasmic Reticulum Stress Protects against Cerebral Ischemia-Reperfusion Injury via the PERK-ATF4-CHOP Pathway.

Wu Y, Fan X, Chen S, Deng L, Jiang L, Yang S, Dong Z
International journal of molecular sciences 2022 Dec 29;24(1)

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SMYD3 associates with the NuRD (MTA1/2) complex to regulate transcription and promote proliferation and invasiveness in hepatocellular carcinoma cells.

Yang Y, Qiu R, Zhao S, Shen L, Tang B, Weng Q, Xu Z, Zheng L, Chen W, Shu G, Wang Y, Zhao Z, Chen M, Ji J
BMC biology 2022 Dec 27;20(1):294

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Targeting Cell Membranes, Depleting ROS by Dithiane and Thioketal-Containing Polymers with Pendant Cholesterols Delivering Necrostatin-1 for Glaucoma Treatment.

Rong R, Zhou X, Liang G, Li H, You M, Liang Z, Zeng Z, Xiao H, Ji D, Xia X
ACS nano 2022 Dec 27;16(12):21225-21239

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4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer.

Wang Y, Lei J, Zhang S, Wang X, Jin J, Liu Y, Gan M, Yuan Y, Sun L, Li X, Han T, Wang JB
Cell death & disease 2022 Dec 27;13(12):1075

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MALAT1 modulates alternative splicing by cooperating with the splicing factors PTBP1 and PSF.

Miao H, Wu F, Li Y, Qin C, Zhao Y, Xie M, Dai H, Yao H, Cai H, Wang Q, Song X, Li L
Science advances 2022 Dec 23;8(51):eabq7289

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Prognostic and therapeutic implication of m6A methylation in Crohn disease.

He Y, Hu Y, Yuan M, Xu W, Du Y, Liu J
Medicine 2022 Dec 23;101(51):e32399

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Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation.

Lim RG, Al-Dalahmah O, Wu J, Gold MP, Reidling JC, Tang G, Adam M, Dansu DK, Park HJ, Casaccia P, Miramontes R, Reyes-Ortiz AM, Lau A, Hickman RA, Khan F, Paryani F, Tang A, Ofori K, Miyoshi E, Michael N, McClure N, Flowers XE, Vonsattel JP, Davidson S, Menon V, Swarup V, Fraenkel E, Goldman JE, Thompson LM
Nature communications 2022 Dec 21;13(1):7791

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Myo-Inositol Supplementation Alleviates Cisplatin-Induced Acute Kidney Injury via Inhibition of Ferroptosis.

Qi H, Deng F, Wang Y, Zhang H, Kanwar YS, Dai Y
Cells 2022 Dec 21;12(1)

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β-hydroxybutyrate inhibits ferroptosis-mediated pancreatic damage in acute liver failure through the increase of H3K9bhb.

Zheng Y, Sun W, Shan C, Li B, Liu J, Xing H, Xu Q, Cui B, Zhu W, Chen J, Liu L, Yang T, Sun N, Li X
Cell reports 2022 Dec 20;41(12):111847

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The Ginsenoside Compound K Suppresses Stem-Cell-like Properties and Colorectal Cancer Metastasis by Targeting Hypoxia-Driven Nur77-Akt Feed-Forward Signaling.

Zhang M, Shi Z, Zhang S, Li X, To SKY, Peng Y, Liu J, Chen S, Hu H, Wong AST, Zeng JZ
Cancers 2022 Dec 20;15(1)

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A multifunctional black phosphorus-based adhesive patch intrinsically induces partial EMT for effective burn wound healing.

Wang X, Tang X, Li N, Sun Y, Yu R, Zhang J, Li D, Yang B, Sun H
Biomaterials science 2022 Dec 20;11(1):235-247

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LncRNA ELF3-AS1 inhibits gastric cancer by forming a negative feedback loop with SNAI2 and regulates ELF3 mRNA stability via interacting with ILF2/ILF3 complex.

Li D, Shen L, Zhang X, Chen Z, Huang P, Huang C, Qin S
Journal of experimental & clinical cancer research : CR 2022 Dec 2;41(1):332

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Targeting regulation of VEGF by BPTF in non-small cell lung cancer and its potential clinical significance.

Dai M, Hua C, Wang M, Gao L, Jiang L, Liu Y
European journal of medical research 2022 Dec 19;27(1):299

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Long noncoding RNA HOTAIR facilitates pulmonary vascular endothelial cell apoptosis via DNMT1 mediated hypermethylation of Bcl-2 promoter in COPD.

Dai Z, Liu X, Zeng H, Chen Y
Respiratory research 2022 Dec 17;23(1):356

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Electroacupuncture Alleviates Neuroinflammation by Inhibiting the HMGB1 Signaling Pathway in Rats with Sepsis-Associated Encephalopathy.

Xin Y, Wang J, Chu T, Zhou Y, Liu C, Xu A
Brain sciences 2022 Dec 17;12(12)

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Fluid shear stress-induced down-regulation of miR-146a-5p inhibits osteoblast apoptosis via targeting SMAD4.

Liu X, Zhang K, Wang L, Geng B, Liu Z, Yi Q, Xia Y
Physiological research 2022 Dec 16;71(6):835-848

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Inhibition of TIGAR Increases Exogenous p53 and Cisplatin Combination Sensitivity in Lung Cancer Cells by Regulating Glycolytic Flux.

Fu J, Yu S, Zhao X, Zhang C, Shen L, Liu Y, Yu H
International journal of molecular sciences 2022 Dec 16;23(24)

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Genome-Wide Analysis of Circular RNAs Reveals circCHRNG Regulates Sheep Myoblast Proliferation via miR-133/SRF and MEF2A Axis.

Liu Y, Chen Q, Bao J, Pu Y, Han J, Zhao H, Ma Y, Zhao Q
International journal of molecular sciences 2022 Dec 16;23(24)

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Polystyrene Microplastics Postpone APAP-Induced Liver Injury through Impeding Macrophage Polarization.

Liu J, Zhang L, Xu F, Meng S, Li H, Song Y
Toxics 2022 Dec 16;10(12)

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The selective NLRP3 inflammasome inhibitor MCC950 improves isoproterenol-induced cardiac dysfunction by inhibiting cardiomyocyte senescence.

Shi Y, Zhao L, Wang J, Liu S, Zhang Y, Qin Q
European journal of pharmacology 2022 Dec 15;937:175364

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Energy sensor AMPK gamma regulates translation via phosphatase PPP6C independent of AMPK alpha.

Zhou Q, Hao B, Cao X, Gao L, Yu Z, Zhao Y, Zhu M, Zhong G, Chi F, Dai X, Mao J, Zhu Y, Rong P, Chen L, Bai X, Ye C, Chen S, Liang T, Li L, Feng XH, Tan M, Zhao B
Molecular cell 2022 Dec 15;82(24):4700-4711.e12

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PRL stimulates mitotic errors by suppressing kinetochore-localized activation of AMPK during mitosis.

Ryu K, Yoshida A, Funato Y, Yamazaki D, Miki H
Cell structure and function 2022 Dec 15;47(2):75-87

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Ferroptosis as a mechanism of oligodendrocyte loss and demyelination in experimental autoimmune encephalomyelitis.

Li X, Chu Y, Ma R, Dou M, Li S, Song Y, Lv Y, Zhu L
Journal of neuroimmunology 2022 Dec 15;373:577995

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Role of Ero1α in cognitive impairment induced by chronic hypoxia.

Zhang N, Shentu Y, Zhu M, Wang H, Yin X, Du C, Xue F, Fan J, Gong Y, Fan X
Brain research 2022 Dec 15;1797:148117

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Fine-tuning of mTOR signaling by the UBE4B-KLHL22 E3 ubiquitin ligase cascade in brain development.

Kong X, Shu X, Wang J, Liu D, Ni Y, Zhao W, Wang L, Gao Z, Chen J, Yang B, Guo X, Wang Z
Development (Cambridge, England) 2022 Dec 15;149(24)

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Coxsackievirus Group B3 Has Oncolytic Activity against Colon Cancer through Gasdermin E-Mediated Pyroptosis.

Zhang Y, Xu T, Tian H, Wu J, Yu X, Zeng L, Liu F, Liu Q, Huang X
Cancers 2022 Dec 15;14(24)

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Matrix protein Tenascin-C promotes kidney fibrosis via STAT3 activation in response to tubular injury.

Xie Q, Zhang M, Mao X, Xu M, Liu S, Shang D, Xu Y, Chen R, Guan Y, Huang X, Zent R, Pozzi A, Hao CM
Cell death & disease 2022 Dec 15;13(12):1044

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Fecal Microbiota Transplantation Alleviated Cerebral Ischemia Reperfusion Injury in Obese Rats.

Xie T, Yang R, Zhang X, Shen X, Yu L, Liao J, Bao T, Fang Q
The Tohoku journal of experimental medicine 2022 Dec 14;259(1):49-55

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miR21 modulates the Hippo signaling pathway via interference with PP2A Bβ to inhibit trophoblast invasion and cause preeclampsia.

Hu M, Zheng Y, Liao J, Wen L, Cheng J, Huang J, Huang B, Lin L, Long Y, Wu Y, Ye X, Fu Y, Qi H, Baker PN, Tong C
Molecular therapy. Nucleic acids 2022 Dec 13;30:143-161

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PINK1/Parkin-Mediated Mitophagy Partially Protects against Inorganic Arsenic-Induced Hepatic Macrophage Polarization in Acute Arsenic-Exposed Mice.

Qu G, Liu Z, Zhang J, Guo Y, Li H, Qu R, Su W, Zhang H, Zhang L, Xu H, Shen F, Jiang S, Liu H, Li J
Molecules (Basel, Switzerland) 2022 Dec 13;27(24)

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Treadmill training mitigates bone deterioration via inhibiting NLRP3/Caspase1/IL-1β signaling in aged rats.

Wu Q, Zhong P, Ning P, Tan L, Huang X, Peng T, Yin L, Luo F, Qu M, Zhou J
BMC musculoskeletal disorders 2022 Dec 13;23(1):1089

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Silibinin Overcomes EMT-Driven Lung Cancer Resistance to New-Generation ALK Inhibitors.

Verdura S, Encinar JA, Teixidor E, Segura-Carretero A, Micol V, Cuyàs E, Bosch-Barrera J, Menendez JA
Cancers 2022 Dec 11;14(24)

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DEXMEDETOMIDINE PREVENTS PDIA3 DECREASE BY ACTIVATING α2-ADRENERGIC RECEPTOR TO ALLEVIATE INTESTINAL I/R IN MICE.

Zhan Y, Chen Z, Qiu Y, Deng Q, Huang W, Wen S, Shen J
Shock (Augusta, Ga.) 2022 Dec 1;58(6):556-564

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Non-canonical phosphoglycerate dehydrogenase activity promotes liver cancer growth via mitochondrial translation and respiratory metabolism.

Shu Y, Hao Y, Feng J, Liu H, Li ST, Feng J, Jiang Z, Ye L, Zhou Y, Sun Y, Zhou Z, Wei H, Gao P, Zhang H, Sun L
The EMBO journal 2022 Dec 1;41(23):e111550

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COOH-terminal fragment of APP interacts with p62, forms an aggregate, and induces autophagic degradation in Alzheimer's cell model.

Tanaka K, Kuramoto K, Nakagawa T, Nomura Y, Ozawa K, Hosoi T
American journal of physiology. Cell physiology 2022 Dec 1;323(6):C1633-C1641

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Aloe polymeric acemannan inhibits the cytokine storm in mouse pneumonia models by modulating macrophage metabolism.

Li L, Xu W, Luo Y, Lao C, Tong X, Du J, Huang B, Li D, Chen J, Ye H, Cong F, Guo X, Li J
Carbohydrate polymers 2022 Dec 1;297:120032

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Alleviating effects of selenium on fluoride-induced testosterone synthesis disorder and reproduction toxicity in rats.

Zhao H, Zhu Y, Zhao Y, Wang T, Li H, Yang J, Cheng X, Wang J, Wang J
Ecotoxicology and environmental safety 2022 Dec 1;247:114249

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Fucoidan ameliorates LPS-induced neuronal cell damage and cognitive impairment in mice.

Wang Y, Wang Q, Duan L, Li X, Yang W, Huang T, Kong M, Guan F, Ma S
International journal of biological macromolecules 2022 Dec 1;222(Pt A):759-771

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Resveratrol activates the SIRT1/PGC-1 pathway in mice to improve synaptic-related cognitive impairment after TBI.

Yu D, Zhao XY, Meng QP, Teng D, Deng K, Lin N
Brain research 2022 Dec 1;1796:148109

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Subchronic Oral Cylindrospermopsin Exposure Alters the Host Gut Microbiome and Is Associated with Progressive Hepatic Inflammation, Stellate Cell Activation, and Mild Fibrosis in a Preclinical Study.

Saha P, Upright M, Bose D, Roy S, Trivedi A, More M, Scott GI, Brooks BW, Chatterjee S
Toxins 2022 Dec 1;14(12)

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Intestinal epithelial β Klotho is a critical protective factor in alcohol-induced intestinal barrier dysfunction and liver injury.

Hou Z, Ding Q, Li Y, Zhao Z, Yan F, Li Y, Wang X, Xu J, Chen W, Wu G, Ruan X, Zhao L
EBioMedicine 2022 Aug;82:104181

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Suppression of nitric oxide synthase aggravates non-alcoholic steatohepatitis and atherosclerosis in SHRSP5/Dmcr rat via acceleration of abnormal lipid metabolism.

Sato I, Yamamoto S, Kakimoto M, Fujii M, Honma K, Kumazaki S, Matsui M, Nakayama H, Kirihara S, Ran S, Usui S, Shinohata R, Kitamori K, Hirohata S, Watanabe S
Pharmacological reports : PR 2022 Aug;74(4):669-683

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Porphyromonas gingivalis lipopolysaccharide affects the angiogenic function of endothelial progenitor cells via Akt/FoxO1 signaling.

Deng H, Gong Y, Chen Y, Zhang G, Chen H, Cheng T, Jin L, Wang Y
Journal of periodontal research 2022 Aug;57(4):859-868

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Mesenchymal stem cell-exosome-mediated matrix metalloproteinase 1 participates in oral leukoplakia and carcinogenesis by inducing angiogenesis.

Li S, Han Y, Lu M, Liu Z, Jin J, Guo Q, Wang Y, Liu H
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2022 Aug;51(7):638-648

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Umbilical cord-derived mesenchymal stem cell conditioned medium reverses neuronal oxidative injury by inhibition of TRPM2 activation and the JNK signaling pathway.

Wang Y, Liu J, Yu B, Jin Y, Li J, Ma X, Yu J, Niu J, Liang X
Molecular biology reports 2022 Aug;49(8):7337-7345

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Oxidative stress and Cx43-mediated apoptosis are involved in PFOS-induced nephrotoxicity.

Tang L, Yu J, Zhuge S, Chen H, Zhang L, Jiang G
Toxicology 2022 Aug;478:153283

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Transcriptional regulator CTR9 promotes hepatocellular carcinoma progression and metastasis via increasing PEG10 transcriptional activity.

Zhang B, Liu ZY, Wu R, Zhang CM, Cao K, Shan WG, Liu Z, Ji M, Tian ZL, Sethi G, Shi HL, Wang RH
Acta pharmacologica Sinica 2022 Aug;43(8):2109-2118

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Alteration of the neuronal and glial cell profiles in Neu1-deficient zebrafish.

Ikeda A, Yamasaki C, Kubo Y, Doi Y, Komamizu M, Komatsu M, Shiozaki K
Glycoconjugate journal 2022 Aug;39(4):499-512

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Extracellular HSP90α promotes cellular senescence by modulating TGF-β signaling in pulmonary fibrosis.

Zhong W, Chen W, Liu Y, Zhang J, Lu Y, Wan X, Qiao Y, Huang H, Zeng Z, Li W, Meng X, Zhao H, Zou M, Cai S, Dong H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Aug;36(8):e22475

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Targeted Disruption of a Proximal Tubule-Specific TMEM174 Gene in Mice Causes Hyperphosphatemia and Vascular Calcification.

Miyazaki-Anzai S, Keenan AL, Blaine J, Miyazaki M
Journal of the American Society of Nephrology : JASN 2022 Aug;33(8):1477-1486

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GRASP55 regulates the unconventional secretion and aggregation of mutant huntingtin.

Ahat E, Bui S, Zhang J, da Veiga Leprevost F, Sharkey L, Reid W, Nesvizhskii AI, Paulson HL, Wang Y
The Journal of biological chemistry 2022 Aug;298(8):102219

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Nuclear ribonucleoprotein RALY targets virus nucleocapsid protein and induces autophagy to restrict porcine epidemic diarrhea virus replication.

Qin W, Kong N, Zhang Y, Dong S, Zhai H, Zhai X, Yang X, Ye C, Ye M, Liu C, Yu L, Zheng H, Yu H, Zhang W, Tong G, Lan D, Tong W, Shan T
The Journal of biological chemistry 2022 Aug;298(8):102190

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MgIG exerts therapeutic effects on crizotinib-induced hepatotoxicity by limiting ROS-mediated autophagy and pyroptosis.

Li M, Wang C, Yu Z, Lan Q, Xu S, Ye Z, Li R, Ying L, Zhang X, Zhou Z
Journal of cellular and molecular medicine 2022 Aug;26(16):4492-4505

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Human breast milk-derived exosomes through inhibiting AT II cell apoptosis to prevent bronchopulmonary dysplasia in rat lung.

Zhou Y, Liu Y, Xu G, Liu L, Li H, Li Y, Yin J, Wang X, Yu Z
Journal of cellular and molecular medicine 2022 Aug;26(15):4169-4182

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The transcription factor TOX is involved in the regulation of T-cell exhaustion in neuroblastoma.

Pei M, Chai W, Wang X, Duan Y, Wang H, Xi Y, Mou W, Wang W, Chen X, Zhang H, Li Q, Song W, Wang H, Ma X, Gui J
Immunology letters 2022 Aug;248:16-25

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Cyclometalated iridium(III) dithioformic acid complexes as mitochondria-targeted imaging and anticancer agents.

Wu Y, Liu J, Shao M, Zhang P, Song S, Yang G, Liu X, Liu Z
Journal of inorganic biochemistry 2022 Aug;233:111855

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Anti-inflammatory Properties of the Alpha-Melanocyte-Stimulating Hormone in Models of Granulomatous Inflammation.

Shahraki AH, Tian R, Zhang C, Fregien NL, Bejarano P, Mirsaeidi M
Lung 2022 Aug;200(4):463-472

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Guanxinning tablet inhibits the interaction between leukocyte integrin Mac-1 and platelet GPIbα for antithrombosis without increased bleeding risk.

Yang QQ, Fang MS, Tu J, Ma QX, Shen LY, Xu YY, Chen J, Chen ML
Chinese journal of natural medicines 2022 Aug;20(8):589-600

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DDIT3/CHOP mediates the inhibitory effect of ER stress on chondrocyte differentiation by AMPKα-SIRT1 pathway.

Yu X, Xu X, Dong W, Yang C, Luo Y, He Y, Jiang C, Wu Y, Wang J
Biochimica et biophysica acta. Molecular cell research 2022 Aug;1869(8):119265

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Cullin-associated and neddylation-dissociated 1 protein (CAND1) governs cardiac hypertrophy and heart failure partially through regulating calcineurin degradation.

Li X, Zhang Y, Zhao Y, Zhou Y, Han Q, Yang Y, Zhang L, Shi L, Jin X, Zhang R, Gao H, Xue G, Li D, Zhang ZR, Lu Y, Yang B, Pan Z
Pharmacological research 2022 Aug;182:106284

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Leonurine alleviates ferroptosis in cisplatin-induced acute kidney injury by activating the Nrf2 signalling pathway.

Hu J, Gu W, Ma N, Fan X, Ci X
British journal of pharmacology 2022 Aug;179(15):3991-4009

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NSUN2-mediated RNA m(5)C modification modulates uveal melanoma cell proliferation and migration.

Luo G, Xu W, Chen X, Wang S, Wang J, Dong F, Hu DN, Reinach PS, Yan D
Epigenetics 2022 Aug;17(8):922-933

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Neuropeptide Y promotes hepatic apolipoprotein A1 synthesis and secretion through neuropeptide Y Y5 receptor.

Liu B, Chen F
Peptides 2022 Aug;154:170824

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Modification of taxifolin particles with an enteric coating material promotes repair of acute liver injury in mice through modulation of inflammation and autophagy signaling pathway.

Ding Q, Chen K, Liu X, Ding C, Zhao Y, Sun S, Zhang Y, Zhang J, Liu S, Liu W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Aug;152:113242

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TPN171H alleviates pulmonary hypertension via inhibiting inflammation in hypoxia and monocrotaline-induced rats.

Zhao C, Hu L, He X, Li L, Yin M, Tettey AT, Wang Y, Shen J, Tang S, Wu C, Li Q, Wang Z, Li X
Vascular pharmacology 2022 Aug;145:107017

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Microbial and metabolic profiles of bronchopulmonary dysplasia and therapeutic effects of potential probiotics Limosilactobacillus reuteri and Bifidobacterium bifidum.

Li Y, He L, Zhao Q, Bo T
Journal of applied microbiology 2022 Aug;133(2):908-921

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Bacillus subtilis WB800N alleviates diabetic wounds in mice by regulating gut microbiota homeostasis and TLR2.

Mi J, Xie C, Zeng L, Zhu Z, Chen N, He Q, Xu X, Xie H, Zhou J, Li L, Liao J
Journal of applied microbiology 2022 Aug;133(2):436-447

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Neomycin inhibits Megalocytivirus infection in fish by antagonizing the increase of intracellular reduced glutathione.

Deng H, Li Y, Li J, Shen W, Chen Q, Weng S, He J, Xu X
Fish & shellfish immunology 2022 Aug;127:148-154

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LncRNA SNHG11 promotes the malignant transformation of human bronchial epithelial cells induced by beryllium sulfate.

Deng W, Sun Z, Chen S, Li G, Liu X, Huang L, Zhang Z
Toxicology research 2022 Aug;11(4):605-615

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High-fructose corn syrup promotes proinflammatory Macrophage activation via ROS-mediated NF-κB signaling and exacerbates colitis in mice.

Wang L, Ji T, Yuan Y, Fu H, Wang Y, Tian S, Hu J, Wang L, Wang Z
International immunopharmacology 2022 Aug;109:108814

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Paeoniflorin ameliorates diabetic liver injury by targeting the TXNIP-mediated NLRP3 inflammasome in db/db mice.

Wang A, Gong Y, Pei Z, Jiang L, Xia L, Wu Y
International immunopharmacology 2022 Aug;109:108792

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Burdock (Arctium lappa L.) leaf flavonoids rich in morin and quercetin 3-O-rhamnoside ameliorate lipopolysaccharide-induced inflammation and oxidative stress in RAW264.7 cells.

Cui J, Zong W, Zhao N, Yuan R
Food science & nutrition 2022 Aug;10(8):2718-2726

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High-affinity SOAT1 ligands remodeled cholesterol metabolism program to inhibit tumor growth.

Wang Z, Wang M, Zhang M, Xu K, Zhang X, Xie Y, Zhang Y, Chang C, Li X, Sun A, He F
BMC medicine 2022 Aug 9;20(1):292

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The inhibitory effect and mechanism of Yi-qi-hua-yu-jie-du decoction on the drug resistance of gastric cancer stem cells based on ABC transporters.

Huang W, Wen F, Gu P, Liu J, Xia Y, Li Y, Zhou J, Song S, Ruan S, Gu S, Chen X, Shu P
Chinese medicine 2022 Aug 9;17(1):93

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Pharmacological induction of AMFR increases functional EAAT2 oligomer levels and reduces epileptic seizures in mice.

Sha L, Li G, Zhang X, Lin Y, Qiu Y, Deng Y, Zhu W, Xu Q
JCI insight 2022 Aug 8;7(15)

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Construction of Attenuated Strains for Red-Spotted Grouper Nervous Necrosis Virus (RGNNV) via Reverse Genetic System.

Lei Y, Xiong Y, Tao D, Wang T, Chen T, Du X, Cao G, Tu J, Dai J
Viruses 2022 Aug 6;14(8)

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The mechanism of the imbalance between proliferation and ferroptosis in pulmonary artery smooth muscle cells based on the activation of SLC7A11.

Hu P, Xu Y, Jiang Y, Huang J, Liu Y, Wang D, Tao T, Sun Z, Liu Y
European journal of pharmacology 2022 Aug 5;928:175093

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Retinal Src homology region 2-containing protein tyrosine phosphatase 2 silencing alleviates diabetic retinopathy via suppressing inflammatory response and oxidative stress by regulating Yes-associated protein 1 activity.

Han N, Su Y, Guo M, Yu L
Experimental animals 2022 Aug 5;71(3):376-384

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Incomplete autophagy promotes the proliferation of Mycoplasma hyopneumoniae through the JNK and Akt pathways in porcine alveolar macrophages.

Wen Y, Chen Z, Tian Y, Yang M, Dong Q, Yang Y, Ding H
Veterinary research 2022 Aug 4;53(1):62

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6-Hydroxydopamine-Induced Neurotoxicity in Rat Model of Parkinson's Disease: Is Reversed via Anti-Oxidative Activities of Curcumin and Aerobic Exercise Therapy.

Sokouti H, Mohajeri D, Nourazar MA
Physiological research 2022 Aug 31;71(4):551-560

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Kaempferol-Driven Inhibition of Listeriolysin O Pore Formation and Inflammation Suppresses Listeria monocytogenes Infection.

Wang T, Liu B, Zhang C, Fang T, Ding Y, Song G, Zhang S, Shi L, Deng X, Wang J
Microbiology spectrum 2022 Aug 31;10(4):e0181022

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GNIP1 functions both as a scaffold protein and an E3 ubiquitin ligase to regulate autophagy in lung cancer.

Zhou F, Liu Y, Ai W, Wang Y, Gan M, Jiang Q, Han T, Wang JB
Cell communication and signaling : CCS 2022 Aug 30;20(1):133

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IFIT3 and IFIT5 Play Potential Roles in Innate Immune Response of Porcine Pulmonary Microvascular Endothelial Cells to Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus.

Wu Y, Song X, Cui D, Zhang T
Viruses 2022 Aug 30;14(9)

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LncRNA H19 inhibits ER stress induced apoptosis and improves diabetic cardiomyopathy by regulating PI3K/AKT/mTOR axis.

Wang S, Duan J, Liao J, Wang Y, Xiao X, Li L, Liu Y, Gu H, Yang P, Fu D, Du J, Li X, Shao M
Aging 2022 Aug 30;14(16):6809-6828

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Dual antioxidant activity and the related mechanisms of a novel pentapeptide GLP4 from the fermented mycelia of Ganoderma lingzhi.

Huang P, Luo FJ, Ma YC, Wang SX, Huang J, Qin DD, Xue FF, Liu BY, Wu Q, Wang XL, Liu GQ
Food & function 2022 Aug 30;13(17):9032-9048

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Circ_0047339 promotes the activation of fibroblasts and affects the development of urethral stricture by targeting the miR-4691-5p/TSP-1 axis.

Ding K, Li D, Zhang R, Zuo M
Scientific reports 2022 Aug 30;12(1):14746

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Downregulation of IL-8 and IL-10 by the Activation of Ca(2+)-Activated K(+) Channel K(Ca)3.1 in THP-1-Derived M(2) Macrophages.

Ohya S, Matsui M, Kajikuri J, Kito H, Endo K
International journal of molecular sciences 2022 Aug 3;23(15)

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Effects of MICU1-Mediated Mitochondrial Calcium Uptake on Energy Metabolism and Quality of Vitrified-Thawed Mouse Metaphase II Oocytes.

Lan T, Zhang K, Lin F, He Q, Wu S, Xu Z, Zhang Y, Quan F
International journal of molecular sciences 2022 Aug 3;23(15)

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Cornuside Is a Potential Agent against Alzheimer's Disease via Orchestration of Reactive Astrocytes.

Shi JZ, Zheng XM, Zhou YF, Yun LY, Luo DM, Hao JJ, Liu PF, Zhang WK, Xu JK, Yan Y, Xie XM, He YY, Pang XB
Nutrients 2022 Aug 3;14(15)

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Staphylococcus aureus-Induced Necroptosis Promotes Mitochondrial Damage in Goat Endometrial Epithelial Cells.

Yi Y, Gao K, Lin P, Chen H, Zhou D, Tang K, Wang A, Jin Y
Animals : an open access journal from MDPI 2022 Aug 29;12(17)

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The mechanism of Yinchenhao decoction in treating obstructive-jaundice-induced liver injury based on Nrf2 signaling pathway.

Liu JJ, Xu Y, Chen S, Hao CF, Liang J, Li ZL
World journal of gastroenterology 2022 Aug 28;28(32):4635-4648

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Rhodococcus equi-Derived Extracellular Vesicles Promoting Inflammatory Response in Macrophage through TLR2-NF-κB/MAPK Pathways.

Xu Z, Hao X, Li M, Luo H
International journal of molecular sciences 2022 Aug 28;23(17)

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Mesenchymal stem cells-derived exosomes prevent sepsis-induced myocardial injury by a CircRTN4/miR-497-5p/MG53 pathway.

Li J, Jiang R, Hou Y, Lin A
Biochemical and biophysical research communications 2022 Aug 27;618:133-140

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ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection.

Karki R, Lee S, Mall R, Pandian N, Wang Y, Sharma BR, Malireddi RS, Yang D, Trifkovic S, Steele JA, Connelly JP, Vishwanath G, Sasikala M, Reddy DN, Vogel P, Pruett-Miller SM, Webby R, Jonsson CB, Kanneganti TD
Science immunology 2022 Aug 26;7(74):eabo6294

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BRAT1 links Integrator and defective RNA processing with neurodegeneration.

Cihlarova Z, Kubovciak J, Sobol M, Krejcikova K, Sachova J, Kolar M, Stanek D, Barinka C, Yoon G, Caldecott KW, Hanzlikova H
Nature communications 2022 Aug 26;13(1):5026

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Inhibition of the PIN1-NRF2/GPX4 axis imparts sensitivity to cisplatin in cervical cancer cells.

Zhang Z, Hu Q, Ye S, Xiang L
Acta biochimica et biophysica Sinica 2022 Aug 25;54(9):1325-1335

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Breaking the Iron Homeostasis: A "Trojan Horse" Self-Assembled Nanodrug Sensitizes Homologous Recombination Proficient Ovarian Cancer Cells to PARP Inhibition.

Li Y, Cen Y, Fang Y, Tang S, Li S, Ren Y, Zhang H, Lu W, Xu J
ACS nano 2022 Aug 23;16(8):12786-12800

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Neu1 deficiency increases the susceptibility of zebrafish to Edwardsiella piscicida infection via lysosomal dysfunction.

Sahashi D, Kubo Y, Ishii M, Ikeda A, Yamasaki C, Komatsu M, Shiozaki K
Gene 2022 Aug 20;836:146667

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Diallyl trisulfide sensitizes radiation therapy on glioblastoma through directly targeting thioredoxin 1.

Tian Y, Ge Z, Xu M, Ge X, Zhao M, Ding F, Yin J, Wang X, You Y, Shi Z, Qian X
Free radical biology & medicine 2022 Aug 20;189:157-168

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GPT2 Is Induced by Hypoxia-Inducible Factor (HIF)-2 and Promotes Glioblastoma Growth.

Zhang B, Chen Y, Bao L, Luo W
Cells 2022 Aug 20;11(16)

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Quantitative Acetylomics Uncover Acetylation-Mediated Pathway Changes Following Histone Deacetylase Inhibition in Anaplastic Large Cell Lymphoma.

Zrimšek M, Kuchaříková H, Draganić K, Dobrovolná P, Heiss Spornberger V, Winkelmayer L, Hassler MR, Lochmanová G, Zdráhal Z, Egger G
Cells 2022 Aug 2;11(15)

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Single-cell atlas of diverse immune populations in the advanced biliary tract cancer microenvironment.

Shi X, Li Z, Yao R, Cheng Q, Li W, Wu R, Xie Z, Zhu Y, Qiu X, Yang S, Zhou T, Hu J, Zhang Y, Wu T, Zhao Y, Zhang Y, Wu J, Wang H, Jiang X, Chen L
NPJ precision oncology 2022 Aug 18;6(1):58

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Developmental differences of in vitro cultured murine bone marrow- and fetal liver-derived megakaryocytes.

Bertović I, Bura A, Jurak Begonja A
Platelets 2022 Aug 18;33(6):887-899

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A Novel Pectin-Like Glycopeptide Isolated from the Fruit of Fructus Mori Impedes Aggregation and Production of Aβ(42).

Li S, Jin C, Gao P, Zhou W, Xiao R, Zhang Z, Liao W, Ding K
Journal of agricultural and food chemistry 2022 Aug 17;70(32):9908-9918

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YTHDC1 is downregulated by the YY1/HDAC2 complex and controls the sensitivity of ccRCC to sunitinib by targeting the ANXA1-MAPK pathway.

Li W, Ye K, Li X, Liu X, Peng M, Chen F, Xiong W, Wang Y, Zhu L
Journal of experimental & clinical cancer research : CR 2022 Aug 17;41(1):250

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Phenolic Acids from Fructus Chebulae Immaturus Alleviate Intestinal Ischemia-Reperfusion Injury in Mice through the PPARα/NF-κB Pathway.

Liu J, Li B, Liu J, Qiu F, Diao Y, Lei Y, Liu J, Zhang W
Molecules (Basel, Switzerland) 2022 Aug 16;27(16)

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Construction of a novel model based on cell-in-cell-related genes and validation of KRT7 as a biomarker for predicting survival and immune microenvironment in pancreatic cancer.

Song J, Ruze R, Chen Y, Xu R, Yin X, Wang C, Xu Q, Zhao Y
BMC cancer 2022 Aug 16;22(1):894

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CD38 Mediates Lung Fibrosis by Promoting Alveolar Epithelial Cell Aging.

Cui H, Xie N, Banerjee S, Dey T, Liu RM, Antony VB, Sanders YY, Adams TS, Gomez JL, Thannickal VJ, Kaminski N, Liu G
American journal of respiratory and critical care medicine 2022 Aug 15;206(4):459-475

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Quantitative Proteomics Explore the Potential Targets and Action Mechanisms of Hydroxychloroquine.

Zhao J, Zhao Z, Hou W, Jiang Y, Liu G, Ren X, Liu K, Liu H, Chen K, Huang H
Molecules (Basel, Switzerland) 2022 Aug 14;27(16)

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Inert Pepper aptamer-mediated endogenous mRNA recognition and imaging in living cells.

Wang Q, Xiao F, Su H, Liu H, Xu J, Tang H, Qin S, Fang Z, Lu Z, Wu J, Weng X, Zhou X
Nucleic acids research 2022 Aug 12;50(14):e84

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Melatonin ameliorates diabetic hyperglycaemia-induced impairment of Leydig cell steroidogenic function through activation of SIRT1 pathway.

Wang P, Zhang S, Lin S, Lv Z
Reproductive biology and endocrinology : RB&E 2022 Aug 12;20(1):117

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The NS4A Protein of Classical Swine Fever Virus Suppresses RNA Silencing in Mammalian Cells.

Qian Q, Xu R, Wang Y, Ma L
Journal of virology 2022 Aug 10;96(15):e0187421

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Hsp70 Inhibits the Replication of Fowl Adenovirus Serotype 4 by Suppressing Viral Hexon with the Assistance of DnaJC7.

Cao J, Liu S, Liu M, Wang S, Bi Z, Fan W, Shi Z, Song S, Yan L
Journal of virology 2022 Aug 10;96(15):e0080722

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The effects of Jiawei Duhuo Jisheng mixture on Wnt/β-catenin signaling pathway in the synovium inflamed by knee osteoarthritis: An in vitro and in vivo experiment.

Shi Q, Huang L, Duan J, Kuang G, Lu M, Tan X
Journal of ethnopharmacology 2022 Aug 10;294:115363

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Jianpi Huayu decoction inhibits the epithelial-mesenchymal transition of hepatocellular carcinoma cells by suppressing exosomal miR-23a-3p/Smad signaling.

Xie CF, Feng KL, Wang JN, Luo R, Fang CK, Zhang Y, Shen CP, Zhong C
Journal of ethnopharmacology 2022 Aug 10;294:115360

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MAB21L1 promotes survival of lens epithelial cells through control of αB-crystallin and ATR/CHK1/p53 pathway.

Xiao Y, Xiang JW, Gao Q, Bai YY, Huang ZX, Hu XH, Wang L, Li DW
Aging 2022 Aug 10;14(15):6128-6148

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MDM2-mediated ubiquitination of LKB1 contributes to the development of diabetic cataract.

Li X, Sun X, Li L, Luo Y, Chi Y, Zheng G
Experimental cell research 2022 Aug 1;417(1):113191

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Multifunctional chitin-based hollow nerve conduit for peripheral nerve regeneration and neuroma inhibition.

Yang X, Huang L, Yi X, Huang S, Duan B, Yu A
Carbohydrate polymers 2022 Aug 1;289:119443

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4-Octyl itaconate suppresses the osteogenic response in aortic valvular interstitial cells via the Nrf2 pathway and alleviates aortic stenosis in mice with direct wire injury.

Peng X, Su S, Zeng J, Xie K, Yang X, Xian G, Xiao Z, Zhu P, Zheng S, Xu D, Zeng Q
Free radical biology & medicine 2022 Aug 1;188:404-418

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The Annexin A2-Notch regulatory loop in hepatocytes promotes liver fibrosis in NAFLD by increasing osteopontin expression.

Wang G, Duan J, Pu G, Ye C, Li Y, Xiu W, Xu J, Liu B, Zhu Y, Wang C
Biochimica et biophysica acta. Molecular basis of disease 2022 Aug 1;1868(8):166413

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Tangeretin suppresses osteoarthritis progression via the Nrf2/NF-κB and MAPK/NF-κB signaling pathways.

Shi Y, Chen J, Li S, Wu Y, Yu C, Ni L, Xiao J, Shao Z, Zhu H, Wang J, Wang X, Zhang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Apr;98:153928

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EML4-ALK G1202R mutation induces EMT and confers resistance to ceritinib in NSCLC cells via activation of STAT3/Slug signaling.

Shen J, Meng Y, Wang K, Gao M, Du J, Wang J, Li Z, Zuo D, Wu Y
Cellular signalling 2022 Apr;92:110264

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c-Myc participates in high glucose-mediated endothelial inflammation via upregulation of IRAK1 expression in diabetic nephropathy.

Hou W, Lu L, Li X, Sun M, Zhu M, Miao C
Cellular signalling 2022 Apr;92:110263

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LPS induces pulmonary microvascular endothelial cell barrier dysfunction by upregulating ceramide production.

Jiang J, Ouyang H, Zhou Q, Tang S, Fang P, Xie G, Yang J, Sun G
Cellular signalling 2022 Apr;92:110250

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Decreased efficacy of the ketamine and scopolamine-induced sustained antidepressant-like effects in rats receiving metformin.

Chuang HW, Wei IH, Li CT, Huang CC
Pharmacological reports : PR 2022 Apr;74(2):340-352

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COP1 Acts as a Ubiquitin Ligase for PCDH9 Ubiquitination and Degradation in Human Glioma.

Zhou K, Wang L, Sun Z, Liu Y, Zhu Y, Liu Z, Zhang B, Shi H
Molecular neurobiology 2022 Apr;59(4):2378-2388

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Interleukin-17A Contributed to the Damage of Blood-CNS Barriers During Streptococcus suis Meningitis.

Xu L, Lu X, Xiao P, Liu R, Xia K, Wu M, Jin M, Zhang A
Molecular neurobiology 2022 Apr;59(4):2116-2128

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A comparison expression analysis of CXCR4, CXCL9 and Caspase-9 in dermal vascular endothelial cells between keloids and normal skin on chemotaxis and apoptosis.

Dong X, Zhang M, Chen Y, Li C, Wang Y, Jin X
Journal of plastic surgery and hand surgery 2022 Apr;56(2):93-102

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Grem1 accelerates nucleus pulposus cell apoptosis and intervertebral disc degeneration by inhibiting TGF-β-mediated Smad2/3 phosphorylation.

Chen S, Lei L, Li Z, Chen F, Huang Y, Jiang G, Guo X, Zhao Z, Liu H, Wang H, Liu C, Zheng Z, Wang J
Experimental & molecular medicine 2022 Apr;54(4):518-530

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Enterobacter cloacae: a villain in CaOx stone disease?

Yang Y, Hong S, Xu J, Li C, Wang S, Xun Y
Urolithiasis 2022 Apr;50(2):177-188

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Linagliptin ameliorates pulmonary fibrosis in systemic sclerosis mouse model via inhibition of endothelial-to-mesenchymal transition.

Pei B, Zhang N, Pang T, Sun G
Molecular and cellular biochemistry 2022 Apr;477(4):995-1007

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Functional characterization of human organic anion transporter 10 (OAT10/SLC22A13) as an orotate transporter.

Shinoda Y, Yamashiro T, Hosooka A, Yasujima T, Yuasa H
Drug metabolism and pharmacokinetics 2022 Apr;43:100443

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Early Aerobic Exercise Promotes Neurological Function Recovery of Rats after Cerebral Ischemia/Reperfusion by Upregulating the Expression of Heat Shock Protein A5.

Peng ZF, Zhang NB, Meng J, Zhang JH
Current medical science 2022 Apr;42(2):267-273

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MicroRNA-22 represses glioma development via activation of macrophage-mediated innate and adaptive immune responses.

Tu J, Fang Y, Han D, Tan X, Xu Z, Jiang H, Wang X, Hong W, Wei W
Oncogene 2022 Apr;41(17):2444-2457

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Interleukin-17A mediates tobacco smoke-induced lung cancer epithelial-mesenchymal transition through transcriptional regulation of ΔNp63α on miR-19.

Xie C, Zhu J, Huang C, Yang X, Wang X, Meng Y, Geng S, Wu J, Shen H, Hu Z, Meng Z, Li X, Zhong C
Cell biology and toxicology 2022 Apr;38(2):273-289

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MiR-125b enhances doxorubicin-induced cardiotoxicity by suppressing the nucleus-cytoplasmic translocation of YAP via targeting STARD13.

Jin X, Yu W, Ye P
Environmental toxicology 2022 Apr;37(4):730-740

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UHRF1 shapes both the trophoblast invasion and decidual macrophage differentiation in early pregnancy.

Liu H, Wang LL, Xu QH, Wang J, Zhang YJ, Luo J, Liao AH
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Apr;36(4):e22247

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TIMP2 mediates endoplasmic reticulum stress contributing to sepsis-induced acute kidney injury.

Jiang N, Huang R, Zhang J, Xu D, Li T, Sun Z, Su L, Peng Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Apr;36(4):e22228

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The alleviative effect of flavonol-type Nrf2 activator rhamnazin from Physalis alkekengi L. var. franchetii (Mast.) Makino on pulmonary disorders.

Wu XY, Wang T, Hu HX, Zhang K, Zhao Y, Zhao BB, Lou HX, Wang XN, Shen T
Phytotherapy research : PTR 2022 Apr;36(4):1692-1707

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FAK regulates cardiomyocyte mitochondrial fission and function through Drp1.

Chang YW, Song ZH, Chen CC
The FEBS journal 2022 Apr;289(7):1897-1910

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Occludin facilitates tumour angiogenesis in bladder cancer by regulating IL8/STAT3 through STAT4.

Yang F, Liu XQ, He JZ, Xian SP, Yang PF, Mai ZY, Li M, Liu Y, Zhang XD
Journal of cellular and molecular medicine 2022 Apr;26(8):2363-2376

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Genetic instability of lung induced by carbon black nanoparticles is related with Plk1 signals changes.

Pei Z, Ning J, Zhang N, Zhang X, Zhang H, Zhang R
NanoImpact 2022 Apr;26:100400

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Molecular mechanism of the TGF‑β/Smad7 signaling pathway in ulcerative colitis.

Bai B, Li H, Han L, Mei Y, Hu C, Mei Q, Xu J, Liu X
Molecular medicine reports 2022 Apr;25(4)

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Exosomes derived from the blood of patients with sepsis regulate apoptosis and aerobic glycolysis in human myocardial cells via the hsa‑miR‑1262/SLC2A1 signaling pathway.

Sun F, Geng H, Sun Y, Feng W, Tian T, Ye L, Lei M
Molecular medicine reports 2022 Apr;25(4)

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USP5 promotes breast cancer cell proliferation and metastasis by stabilizing HIF2α.

Huang W, Liu X, Zhang Y, Deng M, Li G, Chen G, Yu L, Jin L, Liu T, Wang Y, Chen Y
Journal of cellular physiology 2022 Apr;237(4):2211-2219

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UBE2T is upregulated, predicts poor prognosis, and promotes cell proliferation and invasion by promoting epithelial-mesenchymal transition via inhibiting autophagy in an AKT/mTOR dependent manner in ovarian cancer.

Huang W, Huang H, Xiao Y, Wang L, Zhang T, Fang X, Xia X
Cell cycle (Georgetown, Tex.) 2022 Apr;21(8):780-791

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Itaconate attenuates osteoarthritis by inhibiting STING/NF-κB axis in chondrocytes and promoting M2 polarization in macrophages.

Ni L, Lin Z, Hu S, Shi Y, Jiang Z, Zhao J, Zhou Y, Wu Y, Tian N, Sun L, Wu A, Pan Z, Zhang X, Wang X
Biochemical pharmacology 2022 Apr;198:114935

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Pharmacological targeting macrophage phenotype via gut-kidney axis ameliorates renal fibrosis in mice.

Xie Y, Hu X, Li S, Qiu Y, Cao R, Xu C, Lu C, Wang Z, Yang J
Pharmacological research 2022 Apr;178:106161

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Tetrastigma hemsleyanum Diels et Gilg ameliorates lipopolysaccharide induced sepsis via repairing the intestinal mucosal barrier.

Zhan L, Pu J, Zheng J, Hang S, Pang L, Dai M, Ji C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Apr;148:112741

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circHIPK3 regulates cell proliferation and migration by sponging microRNA-124 and regulating serine/threonine kinase 3 expression in esophageal squamous cell carcinoma.

Yao D, Lin S, Chen S, Wang Z
Bioengineered 2022 Apr;13(4):9767-9780

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Human umbilical vein endothelial cells-derived exosomes enhance cardiac function after acute myocardial infarction by activating the PI3K/AKT signaling pathway.

Liu W, Feng Y, Wang X, Ding J, Li H, Guan H, Chen Z
Bioengineered 2022 Apr;13(4):8850-8865

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HSP90 promotes radioresistance of cervical cancer cells via reducing FBXO6-mediated CD147 polyubiquitination.

Song Q, Wen J, Li W, Xue J, Zhang Y, Liu H, Han J, Ning T, Lu Z
Cancer science 2022 Apr;113(4):1463-1474

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The OPG/RANKL/RANK system modulates calcification of common carotid artery in simulated microgravity rats by regulating NF-κB pathway.

Liu H, Ru NY, Cai Y, Lyu Q, Guo CH, Zhou Y, Li SH, Cheng JH, Chang JR, Ma J, Su XL
Canadian journal of physiology and pharmacology 2022 Apr;100(4):324-333

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BRD4 promotes the migration and invasion of bladder cancer cells through the Sonic hedgehog signaling pathway and enhances cisplatin resistance.

Liu T, Zhang Z, Wang C, Huang H, Li Y
Biochemistry and cell biology = Biochimie et biologie cellulaire 2022 Apr;100(2):179-187

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LATS1 is a central signal transmitter for achieving full type-I interferon activity.

Zuo Y, He J, Liu S, Xu Y, Liu J, Qiao C, Zang L, Sun W, Yuan Y, Zhang H, Chen X, Jin L, Miao Y, Huang F, Ren T, Wang J, Qian F, Zhu C, Zhang W, Liu Y, Xu G, Ma F, Zheng H
Science advances 2022 Apr 8;8(14):eabj3887

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Mechanosensitive Piezo1 channels mediate renal fibrosis.

Zhao X, Kong Y, Liang B, Xu J, Lin Y, Zhou N, Li J, Jiang B, Cheng J, Li C, Wang W
JCI insight 2022 Apr 8;7(7)

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Sp1 S-Sulfhydration Induced by Hydrogen Sulfide Inhibits Inflammation via HDAC6/MyD88/NF-κB Signaling Pathway in Adjuvant-Induced Arthritis.

Li M, Hu W, Wang R, Li Z, Yu Y, Zhuo Y, Zhang Y, Wang Z, Qiu Y, Chen K, Ding Q, Qi W, Zhu M, Zhu Y
Antioxidants (Basel, Switzerland) 2022 Apr 7;11(4)

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Stearic Acid Activates the PI3K-mTOR-4EBP1/S6K and mTOR-SREBP-1 Signaling Axes through FATP4-CDK1 To Promote Milk Synthesis in Primary Bovine Mammary Epithelial Cells.

Li F, Hu G, Long X, Cao Y, Li Q, Guo W, Wang J, Liu J, Fu S
Journal of agricultural and food chemistry 2022 Apr 6;70(13):4007-4018

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The Slack Channel Regulates Anxiety-Like Behaviors via Basolateral Amygdala Glutamatergic Projections to Ventral Hippocampus.

Zhang Q, Gao SH, Shen ZS, Wang Y, Hu SW, Duan GB, Liu Y, Zhong DY, Liu J, Sun MH, Zhang X, Cao TY, Cao JL, Tang QY, Zhang Z
The Journal of neuroscience : the official journal of the Society for Neuroscience 2022 Apr 6;42(14):3049-3064

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METTL3-mediated m(6)A modification of TIMP2 mRNA promotes podocyte injury in diabetic nephropathy.

Jiang L, Liu X, Hu X, Gao L, Zeng H, Wang X, Huang Y, Zhu W, Wang J, Wen J, Meng X, Wu Y
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Apr 6;30(4):1721-1740

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TNFAIP8 protein functions as a tumor suppressor in inflammation-associated colorectal tumorigenesis.

Lou Y, Tian X, Sun C, Song M, Han M, Zhao Y, Song Y, Song X, Zhang W, Chen YH, Wang H
Cell death & disease 2022 Apr 6;13(4):311

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Pdcd4 promotes lipid deposition by attenuating PPARα-mediated fatty acid oxidation in hepatocytes.

Du X, Osoro EK, Chen Q, Yan X, Gao D, Wu L, Ren J, Feng L, Wu N, Lu K, Yang X, Zhong B, Han Y, Zhang F, Li D, Lan X, Lu S
Molecular and cellular endocrinology 2022 Apr 5;545:111562

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Positive feedback regulation of microglial glucose metabolism by histone H4 lysine 12 lactylation in Alzheimer's disease.

Pan RY, He L, Zhang J, Liu X, Liao Y, Gao J, Liao Y, Yan Y, Li Q, Zhou X, Cheng J, Xing Q, Guan F, Zhang J, Sun L, Yuan Z
Cell metabolism 2022 Apr 5;34(4):634-648.e6

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miR-AB, a miRNA-based shRNA viral toolkit for multicolor-barcoded multiplex RNAi at a single-cell level.

Wang D, Xiu J, Zhao J, Luo J
EMBO reports 2022 Apr 5;23(4):e53691

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Vitamin K2 Modulates Mitochondrial Dysfunction Induced by 6-Hydroxydopamine in SH-SY5Y Cells via Mitochondrial Quality-Control Loop.

Tang H, Zheng Z, Wang H, Wang L, Zhao G, Wang P
Nutrients 2022 Apr 4;14(7)

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Proteomic Analysis of Vero Cells Infected with Pseudorabies Virus.

Yang X, Xu S, Chen D, Jiang R, Kang H, Ge X, Zhou L, Han J, Zhang Y, Guo X, Yang H
Viruses 2022 Apr 4;14(4)

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Ginsenoside Rk1 regulates glutamine metabolism in hepatocellular carcinoma through inhibition of the ERK/c-Myc pathway.

Lu H, Yin H, Qu L, Ma X, Fu R, Fan D
Food & function 2022 Apr 4;13(7):3793-3811

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Antioxidant Activity of Acanthopanax senticosus Flavonoids in H(2)O(2)-Induced RAW 264.7 Cells and DSS-Induced Colitis in Mice.

Su J, Zhang X, Kan Q, Chu X
Molecules (Basel, Switzerland) 2022 Apr 30;27(9)

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LMOD1, an oncogene associated with Lauren classification, regulates the metastasis of gastric cancer cells through the FAK-AKT/mTOR pathway.

Tan Y, Chen Q, Pan S, An W, Xu H, Xing Y, Zhang J
BMC cancer 2022 Apr 30;22(1):474

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Cdh1 Deficiency Sensitizes TNBC Cells to PARP Inhibitors.

Li J, Lan M, Peng J, Xiong Q, Xu Y, Yang Y, Zhou Y, Liu J, Zeng Z, Yang X, Zhang Z, Zhang P, Zhu Q, Wu W
Genes 2022 Apr 30;13(5)

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Neuron-specific enolase promotes stem cell-like characteristics of small-cell lung cancer by downregulating NBL1 and activating the BMP2/Smad/ID1 pathway.

Lu L, Zha Z, Zhang P, Wang P, Liu X, Fang X, Weng C, Li B, Mao H, Wang L, Guan M, Wu Y, Xu Z, Liu Z, Liu G
Oncogenesis 2022 Apr 29;11(1):21

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Trappc9 Deficiency Impairs the Plasticity of Stem Cells.

Usman M, Li Y, Ke Y, Chhetri G, Islam MA, Wang Z, Li X
International journal of molecular sciences 2022 Apr 28;23(9)

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MicroRNA-146a-5p-modified human umbilical cord mesenchymal stem cells enhance protection against diabetic nephropathy in rats through facilitating M2 macrophage polarization.

Zhang Y, Le X, Zheng S, Zhang K, He J, Liu M, Tu C, Rao W, Du H, Ouyang Y, Li C, Wu D
Stem cell research & therapy 2022 Apr 27;13(1):171

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Mandarin Fish (Siniperca chuatsi) p53 Regulates Glutaminolysis Induced by Virus via the p53/miR145-5p/c-Myc Pathway in Chinese Perch Brain Cells.

Ye C, Liu S, Li N, Zuo S, Niu Y, Lin Q, Liang H, Luo X, Fu X
Microbiology spectrum 2022 Apr 27;10(2):e0272721

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Propofol protects against high glucose-mediated endothelial injury via inhibition of COX2 and iNOS expressions.

Shao J, Ding J, Lu L, Hou W, Wang F, Sun Z, Jiang H, Zhao Y
Acta biochimica et biophysica Sinica 2022 Apr 25;54(4):548-555

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RETREG1-mediated ER-phagy activation induced by glucose deprivation alleviates nucleus pulposus cell damage via ER stress pathway.

Luo R, Liang H, Zhang W, Li G, Zhao K, Hua W, Song Y, Yang C
Acta biochimica et biophysica Sinica 2022 Apr 25;54(4):524-536

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A methylprednisolone-loaded and core-shell nanofiber-covered stent-graft to prevent inflammation and reduce degradation in aortic dissection.

Liu J, Zhu H, Pei Y, Zhang H, Zhou J, Jing Z
Biomaterials research 2022 Apr 25;26(1):15

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Network pharmacology analysis and experimental validation to explore the mechanism of Shenlian extract on myocardial ischemia.

Li JJ, Wang CM, Wang YJ, Yang Q, Cai WY, Li YJ, Song M, Zang YL, Cui XH, Li Q, Chen Y, Weng XG, Zhu XX
Journal of ethnopharmacology 2022 Apr 24;288:114973

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Reversal of Lipid Metabolism Dysregulation by Selenium and Folic Acid Co-Supplementation to Mitigate Pathology in Alzheimer's Disease.

Zhang ZH, Cao XC, Peng JY, Huang SL, Chen C, Jia SZ, Ni JZ, Song GL
Antioxidants (Basel, Switzerland) 2022 Apr 24;11(5)

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A novel oncogenic seRNA promotes nasopharyngeal carcinoma metastasis.

Tan Y, Jiang C, Jia Q, Wang J, Huang G, Tang F
Cell death & disease 2022 Apr 23;13(4):401

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Telomerase RNA TERC and the PI3K-AKT pathway form a positive feedback loop to regulate cell proliferation independent of telomerase activity.

Wu S, Ge Y, Lin K, Liu Q, Zhou H, Hu Q, Zhao Y, He W, Ju Z
Nucleic acids research 2022 Apr 22;50(7):3764-3776

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ORP5 promotes tumor metastasis via stabilizing c-Met in renal cell carcinoma.

Song L, Zhang L, Zhou Y, Shao X, Xu Y, Pei D, Wang Q
Cell death discovery 2022 Apr 21;8(1):219

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Comparative Proteomic Analysis Reveals Mx1 Inhibits Senecavirus A Replication in PK-15 Cells by Interacting with the Capsid Proteins VP1, VP2 and VP3.

Gao H, Xiang Z, Ge X, Zhou L, Han J, Guo X, Chen Y, Zhang Y, Yang H
Viruses 2022 Apr 21;14(5)

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HGF/c-Met pathway facilitates the perineural invasion of pancreatic cancer by activating the mTOR/NGF axis.

Qin T, Xiao Y, Qian W, Wang X, Gong M, Wang Q, An R, Han L, Duan W, Ma Q, Wang Z
Cell death & disease 2022 Apr 21;13(4):387

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[METTL27 is a prognostic biomarker of colon cancer and associated with immune invasion].

Wang K, Zhang J, Deng M, Ju Y, Ouyang M
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2022 Apr 20;42(4):486-497

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Oryzanol alleviates high fat and cholesterol diet-induced hypercholesterolemia associated with the modulation of the gut microbiota in hamsters.

Yan S, Chen J, Zhu L, Guo T, Qin D, Hu Z, Han S, Wang J, Matias FB, Wen L, Luo F, Lin Q
Food & function 2022 Apr 20;13(8):4486-4501

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Age-dependent effects of a high-fat diet combined with dietary advanced glycation end products on cognitive function and protection with voluntary exercise.

Luo L, Li R, Wang G, Chen J, Chen L, Qin LQ, Yu Z, Wan Z
Food & function 2022 Apr 20;13(8):4445-4458

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Exosomal miR-146a-5p and miR-155-5p promote CXCL12/CXCR7-induced metastasis of colorectal cancer by crosstalk with cancer-associated fibroblasts.

Wang D, Wang X, Song Y, Si M, Sun Y, Liu X, Cui S, Qu X, Yu X
Cell death & disease 2022 Apr 20;13(4):380

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Suppression of premature transcription termination leads to reduced mRNA isoform diversity and neurodegeneration.

LaForce GR, Farr JS, Liu J, Akesson C, Gumus E, Pinkard O, Miranda HC, Johnson K, Sweet TJ, Ji P, Lin A, Coller J, Philippidou P, Wagner EJ, Schaffer AE
Neuron 2022 Apr 20;110(8):1340-1357.e7

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TRIM26-mediated degradation of nucleocapsid protein limits porcine reproductive and respiratory syndrome virus-2 infection.

Zhao P, Jing H, Dong W, Duan E, Ke W, Tao R, Li Y, Cao S, Wang H, Zhang Y, Sun Y, Wang J
Virus research 2022 Apr 2;311:198690

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Graphene quantum dots rescue angiogenic retinopathy via blocking STAT3/Periostin/ERK signaling.

Zhao N, Gui X, Fang Q, Zhang R, Zhu W, Zhang H, Li Q, Zhou Y, Zhao J, Cui X, Gao G, Tang H, Shen N, Chen T, Song H, Shen W
Journal of nanobiotechnology 2022 Apr 2;20(1):174

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Flubendazole induces mitochondrial dysfunction and DRP1-mediated mitophagy by targeting EVA1A in breast cancer.

Zhen Y, Yuan Z, Zhang J, Chen Y, Fu Y, Liu Y, Fu L, Zhang L, Zhou XL
Cell death & disease 2022 Apr 19;13(4):375

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Cavβ1 regulates T cell expansion and apoptosis independently of voltage-gated Ca(2+) channel function.

Erdogmus S, Concepcion AR, Yamashita M, Sidhu I, Tao AY, Li W, Rocha PP, Huang B, Garippa R, Lee B, Lee A, Hell JW, Lewis RS, Prakriya M, Feske S
Nature communications 2022 Apr 19;13(1):2033

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Inhibition of KIF23 Alleviates IPAH by Targeting Pyroptosis and Proliferation of PASMCs.

Wu Z, Zhou G, Wang H, Yao P
International journal of molecular sciences 2022 Apr 18;23(8)

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Regulatory variants at 2q33.1 confer schizophrenia risk by modulating distal gene TYW5 expression.

Li S, Li J, Liu J, Wang J, Li X, Huo Y, Li Y, Liu Y, Li M, Xiao X, Luo XJ
Brain : a journal of neurology 2022 Apr 18;145(2):770-786

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β-catenin correlates with the progression of colon cancers and berberine inhibits the proliferation of colon cancer cells by regulating the β-catenin signaling pathway.

Nie Q, Peng WW, Wang Y, Zhong L, Zhang X, Zeng L
Gene 2022 Apr 15;818:146207

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Identified human breast milk compositions effectively inhibit SARS-CoV-2 and variants infection and replication.

Lai X, Yu Y, Xian W, Ye F, Ju X, Luo Y, Dong H, Zhou YH, Tan W, Zhuang H, Li T, Liu X, Ding Q, Xiang K
iScience 2022 Apr 15;25(4):104136

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VPS28 regulates brain vasculature by controlling neuronal VEGF trafficking through extracellular vesicle secretion.

Dong X, Jiang D, Wang L, Zhao J, Yu L, Huang Y, Wu X, Zhu Y, Zhao Y, Zhao Q, Zhang G, Li X
iScience 2022 Apr 15;25(4):104042

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Xihuang pills induce apoptosis in hepatocellular carcinoma by suppressing phosphoinositide 3-kinase/protein kinase-B/mechanistic target of rapamycin pathway.

Teng YJ, Deng Z, Ouyang ZG, Zhou Q, Mei S, Fan XX, Wu YR, Long HP, Fang LY, Yin DL, Zhang BY, Guo YM, Zhu WH, Huang Z, Zheng P, Ning DM, Tian XF
World journal of gastrointestinal oncology 2022 Apr 15;14(4):872-886

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EGFR/MET promotes hepatocellular carcinoma metastasis by stabilizing tumor cells and resisting to RTKs inhibitors in circulating tumor microemboli.

Song S, Yu Z, You Y, Liu C, Xie X, Lv H, Xiao F, Zhu Q, Qin C
Cell death & disease 2022 Apr 15;13(4):351

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Tumor-resident intracellular microbiota promotes metastatic colonization in breast cancer.

Fu A, Yao B, Dong T, Chen Y, Yao J, Liu Y, Li H, Bai H, Liu X, Zhang Y, Wang C, Guo Y, Li N, Cai S
Cell 2022 Apr 14;185(8):1356-1372.e26

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miR-199-5p regulates spermiogenesis at the posttranscriptional level via targeting Tekt1 in allotriploid crucian carp.

Li S, Wang Q, Huang L, Fan S, Li T, Shu Y, Zhang C, Zhou Y, Liu Q, Luo K, Tao M, Liu S
Journal of animal science and biotechnology 2022 Apr 13;13(1):44

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Intestinal Tuft-2 cells exert antimicrobial immunity via sensing bacterial metabolite N-undecanoylglycine.

Xiong Z, Zhu X, Geng J, Xu Y, Wu R, Li C, Fan D, Qin X, Du Y, Tian Y, Fan Z
Immunity 2022 Apr 12;55(4):686-700.e7

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An oxygen-adaptive interaction between SNHG12 and occludin maintains blood-brain barrier integrity.

Li Y, Wei JY, Liu H, Wang KJ, Jin SN, Su ZK, Wang HJ, Shi JX, Li B, Shang DS, Fang WG, Qin XX, Zhao WD, Chen YH
Cell reports 2022 Apr 12;39(2):110656

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Dapagliflozin, sildenafil and their combination in monocrotaline-induced pulmonary arterial hypertension.

Tang Y, Tan S, Li M, Tang Y, Xu X, Zhang Q, Fu Q, Tang M, He J, Zhang Y, Zheng Z, Peng J, Zhu T, Xie W
BMC pulmonary medicine 2022 Apr 12;22(1):142

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Proteomic Studies of the Mechanism of Cytotoxicity, Induced by Palytoxin on HaCaT Cells.

Cheng D, Deng B, Tong Q, Gao S, Xiao B, Zhu M, Ren Z, Wang L, Sun M
Toxins 2022 Apr 10;14(4)

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Chidamide and mitomycin C exert synergistic cytotoxic effects against bladder cancer cells in vitro and suppress tumor growth in a rat bladder cancer model.

Wang SC, Yu CY, Wu YC, Chang YC, Chen SL, Sung WW
Cancer letters 2022 Apr 1;530:8-15

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Microcystin-leucine arginine (MC-LR) induces mouse ovarian inflammation by promoting granulosa cells to produce inflammatory cytokine via activation of cGAS-STING signaling.

Liu K, Zhao X, Guo M, Zhu J, Li D, Ding J, Han X, Wu J
Toxicology letters 2022 Apr 1;358:6-16

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Norcantharidin Induces Immunogenic Cell Death of Bladder Cancer Cells through Promoting Autophagy in Acidic Culture.

Xu L, Su B, Mo L, Zhao C, Zhao Z, Li H, Hu Z, Li J
International journal of molecular sciences 2022 Apr 1;23(7)

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Urolithin A promotes mitophagy and suppresses NLRP3 inflammasome activation in lipopolysaccharide-induced BV2 microglial cells and MPTP-induced Parkinson's disease model.

Qiu J, Chen Y, Zhuo J, Zhang L, Liu J, Wang B, Sun D, Yu S, Lou H
Neuropharmacology 2022 Apr 1;207:108963

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Golgi Phosphoprotein 3 Confers Radioresistance via Stabilizing EGFR in Lung Adenocarcinoma.

Chen G, Kong P, Yang M, Hu W, Prise KM, Yu KN, Cui S, Qin F, Meng G, Almahi WA, Nie L, Han W
International journal of radiation oncology, biology, physics 2022 Apr 1;112(5):1216-1228

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Inhibiting Hyper-O-GlcNAcylation of c-Myc accelerate diabetic wound healing by alleviating keratinocyte dysfunction.

Zhang J, Yang P, Liu D, Gao M, Wang J, Yu T, Zhang X, Liu Y
Burns & trauma 2021;9:tkab031

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Comprehensive analysis of abnormal expression, prognostic value and oncogenic role of the hub gene FN1 in pancreatic ductal adenocarcinoma via bioinformatic analysis and in vitro experiments.

Lei X, Chen G, Li J, Wen W, Gong J, Fu J
PeerJ 2021;9:e12141

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Identification of KIF4A as a pan-cancer diagnostic and prognostic biomarker via bioinformatics analysis and validation in osteosarcoma cell lines.

Pan J, Lei X, Mao X
PeerJ 2021;9:e11455

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Integrated Analysis of Ferroptosis-Related Biomarker Signatures to Improve the Diagnosis and Prognosis Prediction of Ovarian Cancer.

Wang H, Cheng Q, Chang K, Bao L, Yi X
Frontiers in cell and developmental biology 2021;9:807862

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Identification and Validation of HOTAIRM1 as a Novel Biomarker for Oral Squamous Cell Carcinoma.

Yu Y, Niu J, Zhang X, Wang X, Song H, Liu Y, Jiao X, Chen F
Frontiers in bioengineering and biotechnology 2021;9:798584

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Differential Expression Profiles and Potential Intergenerational Functions of tRNA-Derived Small RNAs in Mice After Cadmium Exposure.

Zeng L, Zhou J, Zhang Y, Wang X, Wang M, Su P
Frontiers in cell and developmental biology 2021;9:791784

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Exosomal MIF Derived From Nasopharyngeal Carcinoma Promotes Metastasis by Repressing Ferroptosis of Macrophages.

Chen W, Zuo F, Zhang K, Xia T, Lei W, Zhang Z, Bao L, You Y
Frontiers in cell and developmental biology 2021;9:791187

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PPy@Fe(3)O(4) Nanoparticles Inhibit Tumor Growth and Metastasis Through Chemodynamic and Photothermal Therapy in Non-small Cell Lung Cancer.

Fang D, Jin H, Huang X, Shi Y, Liu Z, Ben S
Frontiers in chemistry 2021;9:789934

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Keratin 17 Is Required for Lipid Metabolism in Keratinocytes and Benefits Epidermal Permeability Barrier Homeostasis.

Pang B, Zhu Z, Xiao C, Luo Y, Fang H, Bai Y, Sun Z, Ma J, Dang E, Wang G
Frontiers in cell and developmental biology 2021;9:779257

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Cadherin-12 Regulates Neurite Outgrowth Through the PKA/Rac1/Cdc42 Pathway in Cortical Neurons.

Guo B, Qi M, Huang S, Zhuo R, Zhang W, Zhang Y, Xu M, Liu M, Guan T, Liu Y
Frontiers in cell and developmental biology 2021;9:768970

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Multiple DSB Resection Activities Redundantly Promote Alternative End Joining-Mediated Class Switch Recombination.

Sun X, Bai J, Xu J, Xi X, Gu M, Zhu C, Xue H, Chen C, Dong J
Frontiers in cell and developmental biology 2021;9:767624

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TGR5 Activation Ameliorates Mitochondrial Homeostasis via Regulating the PKCδ/Drp1-HK2 Signaling in Diabetic Retinopathy.

Zhang MY, Zhu L, Zheng X, Xie TH, Wang W, Zou J, Li Y, Li HY, Cai J, Gu S, Yao Y, Wei TT
Frontiers in cell and developmental biology 2021;9:759421

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LncRNA FEZF1-AS1 Promotes Multi-Drug Resistance of Gastric Cancer Cells via Upregulating ATG5.

Gui Z, Zhao Z, Sun Q, Shao G, Huang J, Zhao W, Kuang Y
Frontiers in cell and developmental biology 2021;9:749129

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Eicosapentaenoic Acid-Induced Autophagy Attenuates Intervertebral Disc Degeneration by Suppressing Endoplasmic Reticulum Stress, Extracellular Matrix Degradation, and Apoptosis.

Lin Z, Ni L, Teng C, Zhang Z, Wu L, Jin Y, Lu X, Lin Z
Frontiers in cell and developmental biology 2021;9:745621

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Autophagy Regulates VDAC3 Ubiquitination by FBXW7 to Promote Erastin-Induced Ferroptosis in Acute Lymphoblastic Leukemia.

Zhu T, Liu B, Wu D, Xu G, Fan Y
Frontiers in cell and developmental biology 2021;9:740884

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TMT-Based Proteomic Explores the Influence of DHEA on the Osteogenic Differentiation of hBMSCs.

Liang X, He M, Zhu B, Zhu Y, He X, Liu D, Wei Q
Frontiers in cell and developmental biology 2021;9:726549

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Lack of MOF Decreases Susceptibility to Hypoxia and Promotes Multidrug Resistance in Hepatocellular Carcinoma via HIF-1α.

Wang M, Liu H, Zhang X, Zhao W, Lin X, Zhang F, Li D, Xu C, Xie F, Wu Z, Yang Q, Li X
Frontiers in cell and developmental biology 2021;9:718707

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ESRRB Facilitates the Conversion of Trophoblast-Like Stem Cells From Induced Pluripotent Stem Cells by Directly Regulating CDX2.

Yu S, Zhang R, Shen Q, Zhu Z, Zhang J, Wu X, Zhao W, Li N, Yang F, Wei H, Hua J
Frontiers in cell and developmental biology 2021;9:712224

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Role of GRK2 in Trophoblast Necroptosis and Spiral Artery Remodeling: Implications for Preeclampsia Pathogenesis.

Lv Z, Xiong LL, Qin X, Zhang H, Luo X, Peng W, Kilby MD, Saffery R, Baker PN, Qi HB
Frontiers in cell and developmental biology 2021;9:694261

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Cardioprotective Role of SIRT5 in Response to Acute Ischemia Through a Novel Liver-Cardiac Crosstalk Mechanism.

Zhou B, Xiao M, Hu H, Pei X, Xue Y, Miao G, Wang J, Li W, Du Y, Zhang P, Wei T
Frontiers in cell and developmental biology 2021;9:687559

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Cyclophosphamide Exposure Causes Long-Term Detrimental Effect of Oocytes Developmental Competence Through Affecting the Epigenetic Modification and Maternal Factors' Transcription During Oocyte Growth.

Yang W, Ma Y, Jin J, Ren P, Zhou H, Xu S, Zhang Y, Hu Z, Rong Y, Dai Y, Zhang Y, Zhang S
Frontiers in cell and developmental biology 2021;9:682060

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The E3 Ligase PIAS1 Regulates p53 Sumoylation to Control Stress-Induced Apoptosis of Lens Epithelial Cells Through the Proapoptotic Regulator Bax.

Nie Q, Chen H, Zou M, Wang L, Hou M, Xiang JW, Luo Z, Gong XD, Fu JL, Wang Y, Zheng SY, Xiao Y, Gan YW, Gao Q, Bai YY, Wang JM, Zhang L, Tang XC, Hu X, Gong L, Liu Y, Li DW
Frontiers in cell and developmental biology 2021;9:660494

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SARS-CoV-2 Host Receptor ACE2 Protein Expression Atlas in Human Gastrointestinal Tract.

An X, Lin W, Liu H, Zhong W, Zhang X, Zhu Y, Wang X, Li J, Sheng Q
Frontiers in cell and developmental biology 2021;9:659809

---

MYC Enhances Cholesterol Biosynthesis and Supports Cell Proliferation Through SQLE.

Yang F, Kou J, Liu Z, Li W, Du W
Frontiers in cell and developmental biology 2021;9:655889

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NTNG1 Modulates Cisplatin Resistance in Epithelial Ovarian Cancer Cells via the GAS6/AXL/Akt Pathway.

Fang S, Luo Y, Zhang Y, Wang H, Liu Q, Li X, Yu T
Frontiers in cell and developmental biology 2021;9:652325

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TAp63α Is Involved in Tobacco Smoke-Induced Lung Cancer EMT and the Anti-cancer Activity of Curcumin via miR-19 Transcriptional Suppression.

Xie C, Zhu J, Yang X, Huang C, Zhou L, Meng Z, Li X, Zhong C
Frontiers in cell and developmental biology 2021;9:645402

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Grb2 Induces Cardiorenal Syndrome Type 3: Roles of IL-6, Cardiomyocyte Bioenergetics, and Akt/mTOR Pathway.

Wang J, Sun X, Wang X, Cui S, Liu R, Liu J, Fu B, Gong M, Wang C, Shi Y, Chen Q, Cai G, Chen X
Frontiers in cell and developmental biology 2021;9:630412

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Deficiency of Sirtuin 1 Impedes Endometrial Decidualization in Recurrent Implantation Failure Patients.

Li J, Qi J, Yao G, Zhu Q, Li X, Xu R, Zhu Z, Zhao H, Wang Y, Ding Y, Sun Y
Frontiers in cell and developmental biology 2021;9:598364

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The Cancer-Testis Long Non-coding RNA PCAT6 Facilitates the Malignant Phenotype of Ovarian Cancer by Sponging miR-143-3p.

Tan X, Shao Y, Teng Y, Liu S, Li W, Xue L, Cao Y, Sun C, Zhang J, Han J, Wu X, Xu H, Xie K
Frontiers in cell and developmental biology 2021;9:593677

---

Zirconia Nanoparticles Induce HeLa Cell Death Through Mitochondrial Apoptosis and Autophagy Pathways Mediated by ROS.

Shang Y, Wang Q, Li J, Liu H, Zhao Q, Huang X, Dong H, Chen W, Gui R, Nie X
Frontiers in chemistry 2021;9:522708

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Inhibition of miR-96-5p May Reduce Aβ42/Aβ40 Ratio via Regulating ATP-binding cassette transporter A1.

Zhu M, Jia L, Jia J
Journal of Alzheimer's disease : JAD 2021;83(1):367-377

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Honokiol Restores Microglial Phagocytosis by Reversing Metabolic Reprogramming.

Li W, Wang S, Zhang H, Li B, Xu L, Li Y, Kong C, Jiao H, Wang Y, Pang Y, Qin W, Jia L, Jia J
Journal of Alzheimer's disease : JAD 2021;82(4):1475-1485

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JMJD1A/NR4A1 Signaling Regulates the Procession of Renal Tubular Epithelial Interstitial Fibrosis Induced by AGEs in HK-2.

Wang S, Zuo A, Jiang W, Xie J, Lin H, Sun W, Zhao M, Xia J, Shao J, Zhao X, Liang D, Yang A, Sun J, Wang M
Frontiers in medicine 2021;8:807694

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A Global Phosphorylation Atlas of Proteins Within Pathological Site of Rotator Cuff Tendinopathy.

Wang Y, Zhang J, Lin Y, Cheng S, Wang D, Rao M, Jiang Y, Huang X, Chen R, Xie Y, Yin P, Cheng B
Frontiers in molecular biosciences 2021;8:787008

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Lanthanum Chloride Sensitizes Cisplatin Resistance of Ovarian Cancer Cells via PI3K/Akt Pathway.

Fang S, Zhang P, Chen X, Liu F, Wang F
Frontiers in medicine 2021;8:776876

---

Auranofin and ICG-001 Emerge Synergistic Anti-tumor Effect on Canine Breast Cancer by Inducing Apoptosis via Mitochondrial Pathway.

Lin Z, Lin Z, Zhao Y, Cheng N, Zhang D, Lin J, Zhang H, Lin D
Frontiers in veterinary science 2021;8:772687

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Maslinic Acid Attenuates Ischemia/Reperfusion Injury-Induced Myocardial Inflammation and Apoptosis by Regulating HMGB1-TLR4 Axis.

Li Q, Xu M, Li Z, Li T, Wang Y, Chen Q, Wang Y, Feng J, Yin X, Lu C
Frontiers in cardiovascular medicine 2021;8:768947

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Spermidine Affects Cardiac Function in Heart Failure Mice by Influencing the Gut Microbiota and Cardiac Galectin-3.

Chen Y, Guo Z, Li S, Liu Z, Chen P
Frontiers in cardiovascular medicine 2021;8:765591

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Multi-Omics Analysis of Mammary Metabolic Changes in Dairy Cows Exposed to Hypoxia.

Kong Z, Li B, Zhou C, He Q, Zheng Y, Tan Z
Frontiers in veterinary science 2021;8:764135

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Loss of Hepatic Surf4 Depletes Lipid Droplets in the Adrenal Cortex but Does Not Impair Adrenal Hormone Production.

Chang X, Zhao Y, Qin S, Wang H, Wang B, Zhai L, Liu B, Gu HM, Zhang DW
Frontiers in cardiovascular medicine 2021;8:764024

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S-Propargyl-Cysteine Attenuates Diabetic Cardiomyopathy in db/db Mice Through Activation of Cardiac Insulin Receptor Signaling.

Li Y, Xie KF, Chang YH, Wang C, Chen Y, Wang MJ, Zhu YC
Frontiers in cardiovascular medicine 2021;8:737191

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The Regulation of Staphylococcus aureus-Induced Inflammatory Responses in Bovine Mammary Epithelial Cells.

Cai M, Fan W, Li X, Sun H, Dai L, Lei D, Dai Y, Liao Y
Frontiers in veterinary science 2021;8:683886

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β-Sitosterol Ameliorates Endometrium Receptivity in PCOS-Like Mice: The Mediation of Gut Microbiota.

Yu Y, Cao Y, Huang W, Liu Y, Lu Y, Zhao J
Frontiers in nutrition 2021;8:667130

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Exosomal MicroRNA-181a Derived From Mesenchymal Stem Cells Improves Gut Microbiota Composition, Barrier Function, and Inflammatory Status in an Experimental Colitis Model.

Gu L, Ren F, Fang X, Yuan L, Liu G, Wang S
Frontiers in medicine 2021;8:660614

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Liraglutide Protects Nucleus Pulposus Cells Against High-Glucose Induced Apoptosis by Activating PI3K/Akt/ mTOR/Caspase-3 and PI3K/Akt/GSK3β/Caspase-3 Signaling Pathways.

Yao M, Zhang J, Li Z, Bai X, Ma J, Li Y
Frontiers in medicine 2021;8:630962

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Identification of the Prognostic Value Among Suppressor Of Cytokine Signaling Family Members in Kidney Renal Clear Cell Carcinoma.

Li C, Zhang W, Fang T, Li N, Wang Y, He L, He H
Frontiers in molecular biosciences 2021;8:585000

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Hydroxysafflor yellow A acutely attenuates blood-brain barrier permeability, oxidative stress, inflammation and apoptosis in traumatic brain injury in rats1.

Xu J, Zhan T, Zheng W, Huang YK, Chen K, Zhang XH, Ren P, Huang X
Acta cirurgica brasileira 2021;35(12):e351202

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Autophagy Prevents Osteocyte Cell Death under Hypoxic Conditions.

Kurihara M, Mukudai Y, Watanabe H, Asakura M, Abe Y, Houri A, Chikuda J, Shimane T, Shirota T
Cells, tissues, organs 2021;210(5-6):326-338

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Long Noncoding RNA HCG9 Promotes Osteosarcoma Progression through RAD51 by Acting as a ceRNA of miR-34b-3p.

Wang L, Li S, Qi L, Ling L
Mediators of inflammation 2021;2021:9978882

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Exosomes Containing LINC00636 Inhibit MAPK1 through the miR-450a-2-3p Overexpression in Human Pericardial Fluid and Improve Cardiac Fibrosis in Patients with Atrial Fibrillation.

Liu L, Luo F, Lei K
Mediators of inflammation 2021;2021:9960241

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Inverse Agonist of Retinoid-Related Orphan Receptor-Alpha Prevents Apoptosis and Degeneration in Nucleus Pulposus Cells via Upregulation of YAP.

Liang T, Qiu J, Li S, Deng Z, Qiu X, Hu W, Li P, Chen T, Liang Z, Zhou H, Gao B, Huang D, Liang A, Gao W
Mediators of inflammation 2021;2021:9954909

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TRIM29 Reverses Oxaliplatin Resistance of P53 Mutant Colon Cancer Cell.

Lei G, Liu S, Yang X, He C
Canadian journal of gastroenterology & hepatology 2021;2021:8870907

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Constitutive Androstane Receptor-Mediated Inhibition of Metformin on Phase II Metabolic Enzyme SULT2A1.

Hu X, Li M, Zhang C, Pang S
International journal of endocrinology 2021;2021:8867218

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Ze-Qi-Tang Formula Induces Granulocytic Myeloid-Derived Suppressor Cell Apoptosis via STAT3/S100A9/Bcl-2/Caspase-3 Signaling to Prolong the Survival of Mice with Orthotopic Lung Cancer.

Xu ZH, Zhu YZ, Su L, Tang XY, Yao C, Jiao XN, Hou YF, Chen X, Wei LY, Wang WT, Wang J, Gong CY, Zhu XD, Zhang F, Zhu SG, Zou CP
Mediators of inflammation 2021;2021:8856326

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ADAM17 Mediates Hypoxia-Induced Keratinocyte Migration via the p38/MAPK Pathway.

Zhu G, Liu J, Wang Y, Jia N, Wang W, Zhang J, Liang Y, Tian H, Zhang J
BioMed research international 2021;2021:8328216

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Tanshinone I Mitigates Steroid-Induced Osteonecrosis of the Femoral Head and Activates the Nrf2 Signaling Pathway in Rats.

Xu X, Shen Y, Lv H, Zhao J, Li X, Gao L, Ren S, Zhang X
Evidence-based complementary and alternative medicine : eCAM 2021;2021:8002161

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Catalpol-Induced AMPK Activation Alleviates Cisplatin-Induced Nephrotoxicity through the Mitochondrial-Dependent Pathway without Compromising Its Anticancer Properties.

Zhang J, Zhao T, Wang C, Meng Q, Huo X, Wang C, Sun P, Sun H, Ma X, Wu J, Liu K
Oxidative medicine and cellular longevity 2021;2021:7467156

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In Hepatocellular Carcinoma, miRNA-296-3p Targets MSL2 and Suppresses Cell Proliferation and Invasion.

Li X, An M, Gao Z
Journal of oncology 2021;2021:7430468

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UBC Mediated by SEPT6 Inhibited the Progression of Prostate Cancer.

Zhang R, Yang Y, Huang H, Li T, Ye L, Lin L, Wei Y
Mediators of inflammation 2021;2021:7393029

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High Methionine Diet-Induced Alzheimer's Disease like Symptoms Are Accompanied by 5-Methylcytosine Elevated Levels in the Brain.

Pi T, Wei S, Jiang Y, Shi JS
Behavioural neurology 2021;2021:6683318

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Neferine Protects against Hypoxic-Ischemic Brain Damage in Neonatal Rats by Suppressing NLRP3-Mediated Inflammasome Activation.

Zhu JJ, Yu BY, Huang XK, He MZ, Chen BW, Chen TT, Fang HY, Chen SQ, Fu XQ, Li PJ, Lin ZL, Zhu JH
Oxidative medicine and cellular longevity 2021;2021:6654954

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The Regulation of ROS- and BECN1-Mediated Autophagy by Human Telomerase Reverse Transcriptase in Glioblastoma.

Ding X, Nie Z, She Z, Bai X, Yang Q, Wang F, Wang F, Geng X
Oxidative medicine and cellular longevity 2021;2021:6636510

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Overexpression of RIPK4 Predicts Poor Prognosis and Promotes Metastasis in Ovarian Cancer.

Liu S, He L, Sheng C, Su R, Wu X, Sun Y, Xi X
BioMed research international 2021;2021:6622439

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Uncovering the Pharmacology of Xiaochaihu Decoction in the Treatment of Acute Pancreatitis Based on the Network Pharmacology.

Zhan L, Pu J, Hu Y, Xu P, Liang W, Ji C
BioMed research international 2021;2021:6621682

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Taohong Siwu-Containing Serum Enhances Angiogenesis in Rat Aortic Endothelial Cells by Regulating the VHL/HIF-1α/VEGF Signaling Pathway.

Tang Z, Li W, Xie H, Jiang S, Pu Y, Xiong H
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6610116

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GDF-15 Suppresses Atherosclerosis by Inhibiting oxLDL-Induced Lipid Accumulation and Inflammation in Macrophages.

Huang H, Chen Z, Li Y, Gong K, Xiao L, Fu H, Yang J, Wang X, Meng Q
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6497568

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Deficiency of MIF Accentuates Overloaded Compression-Induced Nucleus Pulposus Cell Oxidative Damage via Depressing Mitophagy.

Wang Y, Hu Y, Wang H, Liu N, Luo L, Zhao C, Zhou D, Tong H, Li P, Zhou Q
Oxidative medicine and cellular longevity 2021;2021:6192498

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Epigallocatechin-3-Gallate Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease via Inhibition of Apoptosis and Promotion of Autophagy through the ROS/MAPK Signaling Pathway.

Wu D, Liu Z, Wang Y, Zhang Q, Li J, Zhong P, Xie Z, Ji A, Li Y
Oxidative medicine and cellular longevity 2021;2021:5599997

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EZH2 Mediates miR-146a-5p/HIF-1α to Alleviate Inflammation and Glycolysis after Acute Spinal Cord Injury.

Ni S, Yang B, Xia L, Zhang H
Mediators of inflammation 2021;2021:5591582

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A Network Pharmacology Approach for Exploring the Mechanisms of Panax notoginseng Saponins in Ischaemic Stroke.

Wang C, Chen H, Ma ST, Mao BB, Chen Y, Xu HN, Yu H
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5582782

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Inhibition of α-Synuclein Accumulation Improves Neuronal Apoptosis and Delayed Postoperative Cognitive Recovery in Aged Mice.

Li Y, Yuan Y, Li Y, Han D, Liu T, Yang N, Mi X, Hong J, Liu K, Song Y, He J, Zhou Y, Han Y, Shi C, Yu S, Zou P, Guo X, Li Z
Oxidative medicine and cellular longevity 2021;2021:5572899

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POU2F1 Promotes Cell Viability and Tumor Growth in Gastric Cancer through Transcriptional Activation of lncRNA TTC3-AS1.

Wang J, Xiao K, Hou F, Tang L, Luo D, Liu G, Wang Z
Journal of oncology 2021;2021:5570088

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Baihe Jizihuang Tang Ameliorates Chronic Unpredictable Mild Stress-Induced Depression-Like Behavior: Integrating Network Pharmacology and Brain-Gut Axis Evaluation.

Zhu JP, Wu HY, Zi Y, Xia XB, Xie MZ, Yuan ZY
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5554363

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NOX4-Derived ROS Mediates TGF-β1-Induced Metabolic Reprogramming during Epithelial-Mesenchymal Transition through the PI3K/AKT/HIF-1α Pathway in Glioblastoma.

Su X, Yang Y, Guo C, Zhang R, Sun S, Wang Y, Qiao Q, Fu Y, Pang Q
Oxidative medicine and cellular longevity 2021;2021:5549047

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Study on the Antitumor Effect and Glycolysis of Andrographolide in Anaplastic Thyroid Carcinoma.

Yang K, Wu K, Feng J, Yutian L, Zhu X, Xu D
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5526581

---

Berbamine Inhibits Cell Proliferation and Migration and Induces Cell Death of Lung Cancer Cells via Regulating c-Maf, PI3K/Akt, and MDM2-P53 Pathways.

Liu L, Xu Z, Yu B, Tao L, Cao Y
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5517143

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The Key Ingredient Acacetin in Weishu Decoction Alleviates Gastrointestinal Motility Disorder Based on Network Pharmacology Analysis.

Guo X, Xu Y, Tan HL, Wang XJ, Xiao L
Mediators of inflammation 2021;2021:5265444

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The Effect of miR-520b on Macrophage Polarization and T Cell Immunity by Targeting PTEN in Breast Cancer.

Zhu Q, Yuan J, He Y, Hu Y
Journal of oncology 2021;2021:5170496

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OM-MSCs Alleviate the Golgi Apparatus Stress Response following Cerebral Ischemia/Reperfusion Injury via the PEDF-PI3K/Akt/mTOR Signaling Pathway.

He J, Liu J, Huang Y, Tang X, Xiao H, Liu Z, Jiang Z, Zeng L, Hu Z, Lu M
Oxidative medicine and cellular longevity 2021;2021:4805040

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The Dietary Supplement γ-Oryzanol Attenuates Hepatic Ischemia Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress and HMGB1/NLRP3 Inflammasome.

Du Y, Zhong F, Cheng H, Li T, Chen Y, Tan P, Huang M, Liang T, Liu Y, Xia X, Fu W
Oxidative medicine and cellular longevity 2021;2021:4628050

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Ameliorative Effects and Mechanism of Buyang Huanwu Decoction on Pulmonary Vascular Remodeling: Network and Experimental Analyses.

Chen Y, Cui L, Wang C, Liu J, Guo J
Oxidative medicine and cellular longevity 2021;2021:4576071

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Comparative Efficacy of Haizao Yuhu Decoction Composed of Different Varieties of Glycyrrhiza in Goiter Rats.

Chen F, Li N, Xiu L, Liu H, Chen S, He C, Fan A, Yu X, Wang X, Ge C, Huo M, He J, Zhong G
Evidence-based complementary and alternative medicine : eCAM 2021;2021:4343239

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Zinc Regulates Glucose Metabolism of the Spinal Cord and Neurons and Promotes Functional Recovery after Spinal Cord Injury through the AMPK Signaling Pathway.

Hu H, Xia N, Lin J, Li D, Zhang C, Ge M, Tian H, Mei X
Oxidative medicine and cellular longevity 2021;2021:4331625

---

ARHGAP11A Promotes the Malignant Progression of Gastric Cancer by Regulating the Stability of Actin Filaments through TPM1.

Guan X, Guan X, Qin J, Qin L, Shi W, Jiao Z
Journal of oncology 2021;2021:4146910

---

Nrf2 Pathway Ameliorates Bladder Dysfunction in Cyclophosphamide-Induced Cystitis via Suppression of Oxidative Stress.

Ni B, Chen Z, Shu L, Shao Y, Huang Y, Tamrat NE, Wei Z, Shen B
Oxidative medicine and cellular longevity 2021;2021:4009308

---

FAM134B-Mediated ER-phagy Upregulation Attenuates AGEs-Induced Apoptosis and Senescence in Human Nucleus Pulposus Cells.

Luo R, Li S, Li G, Lu S, Zhang W, Liu H, Lei J, Ma L, Ke W, Liao Z, Wang B, Song Y, Wang K, Zhang Y, Yang C
Oxidative medicine and cellular longevity 2021;2021:3843145

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Chlorogenic Acid Alleviates Colon Mucosal Damage Induced by a High-Fat Diet via Gut Microflora Adjustment to Increase Short-Chain Fatty Acid Accumulation in Rats.

Xie MG, Fei YQ, Wang Y, Wang WY, Wang Z
Oxidative medicine and cellular longevity 2021;2021:3456542

---

Electroacupuncture Ameliorates Depression-Like Behaviour in Rats by Enhancing Synaptic Plasticity via the GluN2B/CaMKII/CREB Signalling Pathway.

Zhang K, Liu R, Zhang J, Wei X, Gao Y, Ma W, Li Y, Cai W, Shen W
Evidence-based complementary and alternative medicine : eCAM 2021;2021:2146001

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Inhibition of the PERK/TXNIP/NLRP3 Axis by Baicalin Reduces NLRP3 Inflammasome-Mediated Pyroptosis in Macrophages Infected with Mycobacterium tuberculosis.

Fu Y, Shen J, Li Y, Liu F, Ning B, Zheng Y, Jiang X
Mediators of inflammation 2021;2021:1805147

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Microglia-Derived Exosomes Improve Spinal Cord Functional Recovery after Injury via Inhibiting Oxidative Stress and Promoting the Survival and Function of Endothelia Cells.

Peng W, Wan L, Luo Z, Xie Y, Liu Y, Huang T, Lu H, Hu J
Oxidative medicine and cellular longevity 2021;2021:1695087

---

Inhibiting PP2Acα Promotes the Malignant Phenotype of Gastric Cancer Cells through the ATM/METTL3 Axis.

Cheng Z, Gao S, Liang X, Lian C, Chen J, Fang C
BioMed research international 2021;2021:1015293

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Qingda granule exerts neuroprotective effects against ischemia/reperfusion-induced cerebral injury via lncRNA GAS5/miR-137 signaling pathway.

Zhang L, Cai Q, Lin S, Chen B, Jia B, Ye R, Weygant N, Chu J, Peng J
International journal of medical sciences 2021;18(7):1687-1698

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NSE, positively regulated by LINC00657-miR-93-5p axis, promotes small cell lung cancer (SCLC) invasion and epithelial-mesenchymal transition (EMT) process.

Lu L, Zha Z, Zhang P, Li D, Liu G
International journal of medical sciences 2021;18(16):3768-3779

---

Simultaneous silencing Aurora-A and UHRF1 inhibits colorectal cancer cell growth through regulating expression of DNMT1 and STAT1.

Han J, Chen X, Xu J, Chu L, Li R, Sun N, Jiang Z, Liu H, Ge X, Zheng J, Yang J, Ikezoe T
International journal of medical sciences 2021;18(15):3437-3451

---

GABAB receptor inhibits tumor progression and epithelial-mesenchymal transition via the regulation of Hippo/YAP1 pathway in colorectal cancer.

Wang H, Zhang H, Sun Z, Chen W, Miao C
International journal of biological sciences 2021;17(8):1953-1962

---

Macrophage migration inhibitory factor regulates joint capsule fibrosis by promoting TGF-β1 production in fibroblasts.

Zhang Y, Liu Z, Wang K, Lu S, Fan S, Xu L, Cai B
International journal of biological sciences 2021;17(7):1837-1850

---

Aurka deficiency in the intestinal epithelium promotes age-induced obesity via propionate-mediated AKT activation.

Sun N, Meng F, Zhao J, Li X, Li R, Han J, Chen X, Cheng W, Yang X, Kou Y, Zheng K, Yang J, Ikezoe T
International journal of biological sciences 2021;17(5):1302-1314

---

Targeting HLA-F suppresses the proliferation of glioma cells via a reduction in hexokinase 2-dependent glycolysis.

Chen X, Sun N, Li R, Sang X, Li X, Zhao J, Han J, Yang J, Ikezoe T
International journal of biological sciences 2021;17(5):1263-1276

---

FOXM1-induced miR-552 expression contributes to pancreatic cancer progression by targeting multiple tumor suppressor genes.

Wang X, Dou N, Wang J, Zhang Y, Li Y, Gao Y
International journal of biological sciences 2021;17(4):915-925

---

AKR1B10 confers resistance to radiotherapy via FFA/TLR4/NF-κB axis in nasopharyngeal carcinoma.

Liu X, Hu Z, Qu J, Li J, Gong K, Wang L, Jiang J, Li X, He R, Duan L, Luo W, Xia C, Luo D
International journal of biological sciences 2021;17(3):756-767

---

SOCS2 Suppresses Inflammation and Apoptosis during NASH Progression through Limiting NF-κB Activation in Macrophages.

Li S, Han S, Jin K, Yu T, Chen H, Zhou X, Tan Z, Zhang G
International journal of biological sciences 2021;17(15):4165-4175

---

KMT5A downregulation participated in High Glucose-mediated EndMT via Upregulation of ENO1 Expression in Diabetic Nephropathy.

Lu L, Li X, Zhong Z, Zhou W, Zhou D, Zhu M, Miao C
International journal of biological sciences 2021;17(15):4093-4107

---

The imbalance of PGD2-DPs pathway is involved in the type 2 diabetes brain injury by regulating autophagy.

Yang Y, Xiang P, Chen Q, Luo Y, Wang H, Li H, Yang L, Hu C, Zhang J, Li Y, Xia H, Chen Z, Yang J
International journal of biological sciences 2021;17(14):3993-4004

---

Discovery of a novel HDACi structure that inhibits the proliferation of ovarian cancer cells in vivo and in vitro.

Bai M, Cui M, Li M, Yao X, Wu Y, Zheng L, Sun L, Song Q, Wang S, Liu L, Yu C, Huang Y
International journal of biological sciences 2021;17(13):3493-3507

---

Deubiquitinase PSMD7 promotes the proliferation, invasion, and cisplatin resistance of gastric cancer cells by stabilizing RAD23B.

Wang J, Liu R, Mo H, Xiao X, Xu Q, Zhao W
International journal of biological sciences 2021;17(13):3331-3342

---

NCTD Prevents Renal Interstitial Fibrosis via Targeting Sp1/lncRNA Gm26669 Axis.

Tian J, Xiao Z, Wei J, Shan Y, Zeng D, Tao Y, Fang X, Tang C, Chen X, Li Y
International journal of biological sciences 2021;17(12):3118-3132

---

H2O2 gel bleaching induces cytotoxicity and pain conduction in dental pulp stem cells via intracellular reactive oxygen species on enamel/dentin disc.

Chen C, Huang X, Zhu W, Ding C, Huang P, Li R
PloS one 2021;16(9):e0257221

---

Chirality and asymmetry increase the potency of candidate ADRM1/RPN13 inhibitors.

Anchoori RK, George L, Tseng SH, Lam B, Polkampally S, Amiano AD, Foran P, Tsingine H, Samanapally H, Carrizo Velasquez F, Das S, Xing D, Bin Salam A, Karanam B, Hung CF, Roden RBS
PloS one 2021;16(9):e0256937

---

Harmine inhibits breast cancer cell migration and invasion by inducing the degradation of Twist1.

Nafie E, Lolarga J, Lam B, Guo J, Abdollahzadeh E, Rodriguez S, Glackin C, Liu J
PloS one 2021;16(2):e0247652

---

HIV-1 Vpr protein upregulates microRNA-210-5p expression to induce G2 arrest by targeting TGIF2.

Qiao J, Peng Q, Qian F, You Q, Feng L, Hu S, Liu W, Huang L, Shu X, Sun B
PloS one 2021;16(12):e0261971

---

Inhibition of histone deacetylation with vorinostat does not prevent tunicamycin-mediated acute kidney injury.

Carlisle RE, Farooqi S, Zhang MC, Liu S, Lu C, Phan A, Brimble E, Dickhout JG
PloS one 2021;16(11):e0260519

---

Systematic identification of autophagy-related proteins in Aedes albopictus.

Wang Y, Qiao J, Zhang D, Zhong C, Wang S, Li X, Feng L, Shi S, Wang B, Liu Q
PloS one 2021;16(1):e0245694

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Accurately Controlled Delivery of Temozolomide by Biocompatible UiO-66-NH(2) Through Ultrasound to Enhance the Antitumor Efficacy and Attenuate the Toxicity for Treatment of Malignant Glioma.

Wan Z, Li C, Gu J, Qian J, Zhu J, Wang J, Li Y, Jiang J, Chen H, Luo C
International journal of nanomedicine 2021;16:6905-6922

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Hypermethylation of the Nrf2 Promoter Induces Ferroptosis by Inhibiting the Nrf2-GPX4 Axis in COPD.

Zhang Z, Fu C, Liu J, Sai X, Qin C, Di T, Yang Y, Wu Y, Bian T
International journal of chronic obstructive pulmonary disease 2021;16:3347-3362

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Total Flavonoids of Chuju Decrease Oxidative Stress and Cell Apoptosis in Ischemic Stroke Rats: Network and Experimental Analyses.

Wang C, Chen H, Jiang HH, Mao BB, Yu H
Frontiers in neuroscience 2021;15:772401

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Photobiomodulation Promotes Repair Following Spinal Cord Injury by Regulating the Transformation of A1/A2 Reactive Astrocytes.

Wang X, Zhang Z, Zhu Z, Liang Z, Zuo X, Ju C, Song Z, Li X, Hu X, Wang Z
Frontiers in neuroscience 2021;15:768262

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5-HT(7) Receptor Is Involved in Electroacupuncture Inhibition of Chronic Pain in the Spinal Cord.

Yuan XC, Yan XJ, Tian LX, Guo YX, Zhao YL, Baba SS, Wang YY, Liang LL, Jia H, Xu LP, Li L, Lin H, Huo FQ
Frontiers in neuroscience 2021;15:733779

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IL-17 Inhibits Oligodendrocyte Progenitor Cell Proliferation and Differentiation by Increasing K(+) Channel Kv1.3.

Liu H, Yang X, Yang J, Yuan Y, Wang Y, Zhang R, Xiong H, Xu Y
Frontiers in cellular neuroscience 2021;15:679413

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Injection of Anti-proBDNF Attenuates Hippocampal-Dependent Learning and Memory Dysfunction in Mice With Sepsis-Associated Encephalopathy.

Cui YH, Zhou SF, Liu Y, Wang S, Li F, Dai RP, Hu ZL, Li CQ
Frontiers in neuroscience 2021;15:665757

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Tetramethylpyrazine Alleviates Behavioral and Psychological Symptoms of Dementia Through Facilitating Hippocampal Synaptic Plasticity in Rats With Chronic Cerebral Hypoperfusion.

Tan Z, Qiu J, Zhang Y, Yang Q, Yin X, Li J, Liu G, Li H, Yang G
Frontiers in neuroscience 2021;15:646537

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Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice.

Chang Y, Yao Y, Ma R, Wang Z, Hu J, Wu Y, Jiang X, Li L, Li G
Frontiers in neuroscience 2021;15:620176

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IRE1α-XBP1 Affects the Mitochondrial Function of Aβ25-35-Treated SH-SY5Y Cells by Regulating Mitochondria-Associated Endoplasmic Reticulum Membranes.

Chu B, Li M, Cao X, Li R, Jin S, Yang H, Xu L, Wang P, Bi J
Frontiers in cellular neuroscience 2021;15:614556

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Oroxin B Attenuates Ovariectomy-Induced Bone Loss by Suppressing Osteoclast Formation and Activity.

Huang JM, Wang CZ, Lu SY, Wang Z, Yan ZQ
Drug design, development and therapy 2021;15:4811-4825

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Doxazosin Attenuates Liver Fibrosis by Inhibiting Autophagy in Hepatic Stellate Cells via Activation of the PI3K/Akt/mTOR Signaling Pathway.

Xiu AY, Ding Q, Li Z, Zhang CQ
Drug design, development and therapy 2021;15:3643-3659

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Baicalin Alleviates Oxidative Stress and Inflammation in Diabetic Nephropathy via Nrf2 and MAPK Signaling Pathway.

Ma L, Wu F, Shao Q, Chen G, Xu L, Lu F
Drug design, development and therapy 2021;15:3207-3221

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Selective Inhibition of 11β-Hydroxysteroid Dehydrogenase Type 1 Attenuates High-Fat Diet-Induced Hepatic Steatosis in Mice.

Li H, Sheng J, Wang J, Gao H, Yu J, Ding G, Ding N, He W, Zha J
Drug design, development and therapy 2021;15:2309-2324

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ADAM17 and NF-κB p65 form a positive feedback loop that facilitates human esophageal squamous cell carcinoma cell viability.

Gao L, Liu H, Xu R, Qiu J, Peng X, Yang Y, Zhang D, Qian J
International journal of clinical and experimental pathology 2021;14(7):845-854

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Significance of TEAD Family in Diagnosis, Prognosis and Immune Response for Ovarian Serous Carcinoma.

Ren X, Wang X, Peng B, Liang Q, Cai Y, Gao K, Hu Y, Xu Z, Yan Y
International journal of general medicine 2021;14:7133-7143

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Ginsenoside Rg1 Inhibits Microglia Pyroptosis Induced by Lipopolysaccharide Through Regulating STAT3 Signaling.

Yao Y, Li C, Qian F, Zhao Y, Shi X, Hong D, Ai Q, Zhong L
Journal of inflammation research 2021;14:6619-6632

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Gαi1 Promoted Proliferation, Migration and Invasion via Activating the Akt-mTOR/Erk-MAPK Signaling Pathway in Renal Cell Carcinoma.

Chen Z, Zhang Y, Wu X, Zhang J, Xu W, Shen C, Zheng B
OncoTargets and therapy 2021;14:2941-2952

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Regulation of IFN-Is by MEF2D Promotes Inflammatory Homeostasis in Microglia.

Lu F, Wang R, Xia L, Nie T, Gao F, Yang S, Huang L, Shao K, Liu J, Yang Q
Journal of inflammation research 2021;14:2851-2863

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GADD45B Facilitates Metastasis of Ovarian Cancer Through Epithelial-Mesenchymal Transition.

Gong L, Cai L, Li G, Cai J, Yi X
OncoTargets and therapy 2021;14:255-269

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Upregulation of Neuronal Cylindromatosis Expression is Essential for Electroacupuncture-Mediated Alleviation of Neuroinflammatory Injury by Regulating Microglial Polarization in Rats Subjected to Focal Cerebral Ischemia/Reperfusion.

Lin X, Zhan J, Jiang J, Ren Y
Journal of inflammation research 2021;14:2061-2078

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Orexin-A Attenuates Inflammatory Responses in Lipopolysaccharide-Induced Neural Stem Cells by Regulating NF-KB and Phosphorylation of MAPK/P38/Erk Pathways.

Ye W, Yan Y, Tang Y, Dong X, Chen G, Kang J, Huang L, Xiong Q, Feng Z
Journal of inflammation research 2021;14:2007-2017

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MiRNA-223-3p Affects Mantle Cell Lymphoma Development by Regulating the CHUK/NF-ƘB2 Signaling Pathway.

Yuan J, Zhang Q, Wu S, Yan S, Zhao R, Sun Y, Tian X, Zhou K
OncoTargets and therapy 2021;14:1553-1564

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The Significance of HOXC11 and LSH in Survival Prediction in Gastric Adenocarcinoma.

Peng X, Sun J, Long Y, Xiao D, Zhou J, Tao Y, Liu S
OncoTargets and therapy 2021;14:1517-1529

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Network pharmacology-guided mechanism study uncovers inhibitory effect of Mahuang Decoction on lung cancer growth by impeding Akt/ERK signaling pathways.

Pan Y, Chen Y, Wu C, Ai J, Wang Y, Jia J, Liu L
American journal of translational research 2021;13(4):2094-2110

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Myosin 1b promotes migration, invasion and glycolysis in cervical cancer via ERK/HIF-1α pathway.

Wen LJ, Hu XL, Li CY, Liu J, Li ZY, Li YZ, Zhou JY
American journal of translational research 2021;13(11):12536-12548

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Sevoflurane prevents pulmonary vascular remodeling and right ventricular dysfunction in pulmonary arterial hypertension in rats.

Zhai W, Li Y, Luo Y, Gao W, Liu S, Han J, Geng J
American journal of translational research 2021;13(10):11302-11315

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Dura cells in the etiopathogenesis of Crouzon syndrome: the effects of FGFR2 mutations in the dura cells on the proliferation of osteoblasts through the hippo/YAP mediated transcriptional regulation pathway.

Dong XH, Zhang MZ, Lai CZ, Li CC, Du L, Song GD, Zong XL, Jin XL
American journal of translational research 2021;13(10):11255-11270

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Schisandrin C attenuates renal damage in diabetic nephropathy by regulating macrophage polarization.

Wang Y, Cui J, Liu M, Shao Y, Dong X
American journal of translational research 2021;13(1):210-222

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Overexpression of the lncRNA AC012213.3 Promotes Proliferation, Migration and Invasion of Breast Cancer via RAD54B/PI3K/AKT Axis and is Associated with Worse Patient Prognosis.

Zhong H, Zeng G, He L
Cancer management and research 2021;13:7213-7223

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Calcitriol Alleviates MPP(+)- and MPTP-Induced Parthanatos Through the VDR/PARP1 Pathway in the Model of Parkinson's Disease.

Hu J, Wu J, Wan F, Kou L, Yin S, Sun Y, Li Y, Zhou Q, Wang T
Frontiers in aging neuroscience 2021;13:657095

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ZNF750 exerted its Antitumor Action in Oral Squamous Cell Carcinoma by regulating E2F2.

Yang HL, Xu C, Yang YK, Tang WQ, Hong M, Pan L, Chen HY
Journal of Cancer 2021;12(24):7266-7276

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LncRNA TMEM220-AS1 suppresses hepatocellular carcinoma cell proliferation and invasion by regulating the TMEM220/β-catenin axis.

Liu Y, Liu R, Zhao J, Zeng Z, Shi Z, Lu Q, Guo J, Li L, Yao Y, Liu X, Xu Q
Journal of Cancer 2021;12(22):6805-6813

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LncRNA MALAT1 was regulated by HPV16 E7 independently of pRB in cervical cancer cells.

Wang T, Zhang W, Huang W, Hua Z, Li S
Journal of Cancer 2021;12(21):6344-6355

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Inositol hexaphosphate sensitizes hepatocellular carcinoma to oxaliplatin relating inhibition of CCN2-LRP6-β-catenin-ABCG1 signaling pathway.

Liao X, Zhang Y, Xu B, Ali A, Liu X, Jia Q
Journal of Cancer 2021;12(20):6071-6080

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Caspase-11-Mediated Hepatocytic Pyroptosis Promotes the Progression of Nonalcoholic Steatohepatitis.

Zhu Y, Zhao H, Lu J, Lin K, Ni J, Wu G, Tang H
Cellular and molecular gastroenterology and hepatology 2021;12(2):653-664

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SLC39A7 promotes malignant behaviors in glioma via the TNF-α-mediated NF-κB signaling pathway.

Chen L, Zhou J, Li L, Zhao J, Li H, Zheng W, Xu J, Jing Z
Journal of Cancer 2021;12(15):4530-4541

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Demethylzelasteral inhibits proliferation and EMT via repressing Wnt/β-catenin signaling in esophageal squamous cell carcinoma.

Yu J, Wang W, Liu B, Gu J, Chen S, Cui Y, Sun G
Journal of Cancer 2021;12(13):3967-3975

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CDK5 Knockdown inhibits proliferation and induces apoptosis and Cell Cycle Arrest in Human Glioblastoma.

Zhou Y, Wang X, Lv P, Yu H, Jiang X
Journal of Cancer 2021;12(13):3958-3966

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Proteomic Analysis of the Alterations in Follicular Fluid Proteins During Oocyte Maturation in Humans.

Wang C, Fei X, Zhang H, Zhou W, Cheng Z, Feng Y
Frontiers in endocrinology 2021;12:830691

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Diosgenin From Dioscorea Nipponica Rhizoma Against Graves' Disease-On Network Pharmacology and Experimental Evaluation.

Xin J, Cheng W, Yu Y, Chen J, Zhang X, Shao S
Frontiers in pharmacology 2021;12:806829

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Exploring the Pharmacological Mechanisms of Xihuang Pills Against Prostate Cancer via Integrating Network Pharmacology and Experimental Validation In Vitro and In Vivo.

Wu Y, You X, Lin Q, Xiong W, Guo Y, Huang Z, Dai X, Chen Z, Mei S, Long Y, Tian X, Zhou Q
Frontiers in pharmacology 2021;12:791269

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Proteomics Study Reveals the Anti-Depressive Mechanisms and the Compatibility Advantage of Chaihu-Shugan-San in a Rat Model of Chronic Unpredictable Mild Stress.

Zhu X, Li T, Hu E, Duan L, Zhang C, Wang Y, Tang T, Yang Z, Fan R
Frontiers in pharmacology 2021;12:791097

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Punicalin Attenuates Breast Cancer-Associated Osteolysis by Inhibiting the NF-κB Signaling Pathway of Osteoclasts.

Li T, Jiang G, Hu X, Yang D, Tan T, Gao Z, Chen Z, Xiang C, Li S, Ouyang Z, Guo X
Frontiers in pharmacology 2021;12:789552

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Baicalein Alleviates Osteoarthritis Progression in Mice by Protecting Subchondral Bone and Suppressing Chondrocyte Apoptosis Based on Network Pharmacology.

Yi N, Mi Y, Xu X, Li N, Zeng F, Yan K, Tan K, Kuang G, Lu M
Frontiers in pharmacology 2021;12:788392

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Exercise Capacity Is Improved by Levosimendan in Heart Failure and Sarcopenia via Alleviation of Apoptosis of Skeletal Muscle.

Wang D, Song M, Shen LF, Han L, Zhu P, Jia X, Shang GK, Cao Y, Zhang W, Zhong M, Wang ZH
Frontiers in physiology 2021;12:786895

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Chitosan Protects Immunosuppressed Mice Against Cryptosporidium parvum Infection Through TLR4/STAT1 Signaling Pathways and Gut Microbiota Modulation.

Rahman SU, Gong H, Mi R, Huang Y, Han X, Chen Z
Frontiers in immunology 2021;12:784683

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Integrated Network Pharmacology and Lipidomics to Reveal the Inhibitory Effect of Qingfei Oral Liquid on Excessive Autophagy in RSV-Induced Lung Inflammation.

Lin L, An L, Chen H, Feng L, Lu M, Liu Y, Chu C, Shan J, Xie T, Wang X, Wang S
Frontiers in pharmacology 2021;12:777689

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Inhibiting YAP in Endothelial Cells From Entering the Nucleus Attenuates Blood-Brain Barrier Damage During Ischemia-Reperfusion Injury.

Gong S, Ma H, Zheng F, Huang J, Zhang Y, Yu B, Li F, Kou J
Frontiers in pharmacology 2021;12:777680

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Acid-Sensing Ion Channel 1/Calpain1 Activation Impedes Macrophage ATP-Binding Cassette Protein A1-Mediated Cholesterol Efflux Induced by Extracellular Acidification.

Wang YM, Tan MY, Zhang RJ, Qiu MY, Fu YS, Xie XJ, Gu HF
Frontiers in physiology 2021;12:777386

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Activation of TAF9 via Danshensu-Induced Upregulation of HDAC1 Expression Alleviates Non-alcoholic Fatty Liver Disease.

Wang R, Wang Z, Sun R, Fu R, Sun Y, Zhu M, Geng Y, Gao D, Tian X, Zhao Y, Yao J
Frontiers in pharmacology 2021;12:775528

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Enhancing Fatty Acids Oxidation via L-Carnitine Attenuates Obesity-Related Atrial Fibrillation and Structural Remodeling by Activating AMPK Signaling and Alleviating Cardiac Lipotoxicity.

Zhang Y, Fu Y, Jiang T, Liu B, Sun H, Zhang Y, Fan B, Li X, Qin X, Zheng Q
Frontiers in pharmacology 2021;12:771940

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CircEpc1 Promotes Ricin Toxin-Induced Inflammation via Activation of NF-κB and MAPK Signaling Pathways by Sponging miR-5114.

Dong M, Zhang X, Yu H, Wang Y, Chang Y, Sun C, Zhang J, Zhao N, Yu K, Sun G, Zhao G, Xu N, Liu W
Frontiers in pharmacology 2021;12:767900

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Screening and Functional Analysis of TEK Mutations in Chinese Children With Primary Congenital Glaucoma.

Qiao Y, Chen Y, Tan C, Sun X, Chen X, Chen J
Frontiers in genetics 2021;12:764509

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circKLF4 Upregulates Klf4 and Endoglin to Promote Odontoblastic Differentiation of Mouse Dental Papilla Cells via Sponging miRNA-1895 and miRNA-5046.

Zhang Y, Zhang H, Yuan G, Yang G
Frontiers in physiology 2021;12:760223

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Trametinib Inhibits the Growth and Aerobic Glycolysis of Glioma Cells by Targeting the PKM2/c-Myc Axis.

Gao M, Yang J, Gong H, Lin Y, Liu J
Frontiers in pharmacology 2021;12:760055

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Dauricine Attenuates Vascular Endothelial Inflammation Through Inhibiting NF-κB Pathway.

Hu J, Chen R, An J, Wang Y, Liang M, Huang K
Frontiers in pharmacology 2021;12:758962

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The ALDH Family Contributes to Immunocyte Infiltration, Proliferation and Epithelial-Mesenchymal Transformation in Glioma.

Wang Z, Mo Y, Tan Y, Wen Z, Dai Z, Zhang H, Zhang X, Feng S, Liang X, Song T, Cheng Q
Frontiers in immunology 2021;12:756606

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β2-Adrenergic Receptor Enhances the Alternatively Activated Macrophages and Promotes Biliary Injuries Caused by Helminth Infection.

Koda S, Zhang B, Zhou QY, Xu N, Li J, Liu JX, Liu M, Lv ZY, Wang JL, Shi Y, Gao S, Yu Q, Li XY, Xu YH, Chen JX, Tekengne BOT, Adzika GK, Tang RX, Sun H, Zheng KY, Yan C
Frontiers in immunology 2021;12:754208

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Characterization of Pathogenesis and Inflammatory Responses to Experimental Parechovirus Encephalitis.

Jan MW, Su HL, Chang TH, Tsai KJ
Frontiers in immunology 2021;12:753683

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The Effect of Ellagic Acid on Hepatic Lipid Metabolism and Antioxidant Activity in Mice.

Xu Q, Li S, Tang W, Yan J, Wei X, Zhou M, Diao H
Frontiers in physiology 2021;12:751501

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SARS-CoV-2 Nsp5 Activates NF-κB Pathway by Upregulating SUMOylation of MAVS.

Li W, Qiao J, You Q, Zong S, Peng Q, Liu Y, Hu S, Liu W, Li S, Shu X, Sun B
Frontiers in immunology 2021;12:750969

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Rhein Relieves Oxidative Stress in an Aβ(1-42) Oligomer-Burdened Neuron Model by Activating the SIRT1/PGC-1α-Regulated Mitochondrial Biogenesis.

Yin Z, Geng X, Zhang Z, Wang Y, Gao X
Frontiers in pharmacology 2021;12:746711

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Anlotinib Inhibits PFKFB3-Driven Glycolysis in Myofibroblasts to Reverse Pulmonary Fibrosis.

Chen W, Zhang J, Zhong W, Liu Y, Lu Y, Zeng Z, Huang H, Wan X, Meng X, Zou F, Cai S, Dong H
Frontiers in pharmacology 2021;12:744826

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Mechanisms Underlying Gastrodin Alleviating Vincristine-Induced Peripheral Neuropathic Pain.

Wang X, Zhang B, Li X, Liu X, Wang S, Xie Y, Pi J, Yang Z, Li J, Jia Q, Zhang Y
Frontiers in pharmacology 2021;12:744663

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Identification of a Novel Gene Correlated With Vascular Smooth Muscle Cells Proliferation and Migration in Chronic Thromboembolic Pulmonary Hypertension.

Wang F, Sun C, Lv X, Sun M, Si C, Zhen Y, Guo J, Sun W, Ye Z, Wen J, Liu P
Frontiers in physiology 2021;12:744219

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Morchella importuna Flavones Improve Intestinal Integrity in Dextran Sulfate Sodium-Challenged Mice.

Xu Y, Xie L, Tang J, He X, Zhang Z, Chen Y, Zhou J, Gan B, Peng W
Frontiers in microbiology 2021;12:742033

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Probiotic Interventions Alleviate Food Allergy Symptoms Correlated With Cesarean Section: A Murine Model.

Jin BY, Li Z, Xia YN, Li LX, Zhao ZX, Li XY, Li Y, Li B, Zhou RC, Fu SC, Li SY, Li YQ
Frontiers in immunology 2021;12:741371

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High-Salt Attenuates the Efficacy of Dapagliflozin in Tubular Protection by Impairing Fatty Acid Metabolism in Diabetic Kidney Disease.

Zou M, Chen Y, Zheng Z, Sheng S, Jia Y, Wang X, Ren S, Yang Y, Li X, Dong W, Guan M, Zhang Q, Xue Y
Frontiers in pharmacology 2021;12:741087

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Tetrandrine Modulates Rheb-mTOR Signaling-Mediated Selective Autophagy and Protects Pulmonary Fibrosis.

Liu Y, Zhong W, Zhang J, Chen W, Lu Y, Qiao Y, Zeng Z, Huang H, Cai S, Dong H
Frontiers in pharmacology 2021;12:739220

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MIR337-3p Enhances Mycobacterial Pathogenicity Involving TLR4/MYD88 and STAT3 Signals, Impairing VDR Antimicrobial Response and Fast-Acting Immunity.

Liang S, Huang G, Wu T, Peng Y, Liu X, Ji X, Sha W, Wang F, Shen L, Shen H
Frontiers in immunology 2021;12:739219

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Paeoniflorin Suppresses TBHP-Induced Oxidative Stress and Apoptosis in Human Umbilical Vein Endothelial Cells via the Nrf2/HO-1 Signaling Pathway and Improves Skin Flap Survival.

Jiang J, Dong C, Zhai L, Lou J, Jin J, Cheng S, Chen Z, Guo X, Lin D, Ding J, Gao W
Frontiers in pharmacology 2021;12:735530

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β-Adrenergic Receptor Inhibitor and Oncolytic Herpesvirus Combination Therapy Shows Enhanced Antitumoral and Antiangiogenic Effects on Colorectal Cancer.

Hu J, Chen C, Lu R, Zhang Y, Wang Y, Hu Q, Li W, Wang S, Jing O, Yi H, Zhang W, Chen L, Huang W, Luo J, McLeod HL, Xu R, He Y
Frontiers in pharmacology 2021;12:735278

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Polysaccharides Extracted From Panax Ginseng C.A. Mey Enhance Complement Component 4 Biosynthesis in Human Hepatocytes.

Liu S, Liu F, Wang T, Liu J, Hu C, Sun L, Wang G
Frontiers in pharmacology 2021;12:734394

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Berberine Reduces Lipid Accumulation by Promoting Fatty Acid Oxidation in Renal Tubular Epithelial Cells of the Diabetic Kidney.

Rong Q, Han B, Li Y, Yin H, Li J, Hou Y
Frontiers in pharmacology 2021;12:729384

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Clozapine Induced Disturbances in Hepatic Glucose Metabolism: The Potential Role of PGRMC1 Signaling.

Cao T, Chen Q, Zhang B, Wu X, Zeng C, Zhang S, Cai H
Frontiers in endocrinology 2021;12:727371

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Association of Pericyte Loss With Microthrombosis After Subarachnoid Hemorrhage in ApoE-Deficient Mice.

Pang J, Wu Y, Peng J, Yang P, Chen L, Jiang Y
Frontiers in neurology 2021;12:726520

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Protective Effect of Oxytocin on Ventilator-Induced Lung Injury Through NLRP3-Mediated Pathways.

Yang X, An X, Wang C, Gao F, Lin Y, Chen W, Deng Q, Xu D, Li S, Zhang P, Sun B, Hou Y, Wu J
Frontiers in pharmacology 2021;12:722907

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Ddb1 Is Essential for the Expansion of CD4(+) Helper T Cells by Regulating Cell Cycle Progression and Cell Death.

Yang L, Chen W, Li L, Xiao Y, Fan S, Zhang Q, Xia T, Li M, Hong Y, Zhao T, Li Q, Liu WH, Xiao N
Frontiers in immunology 2021;12:722273

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Identification of Potential Prognostic Biomarker for Predicting Survival in Multiple Myeloma Using Bioinformatics Analysis and Experiments.

Zhou J, Zhang M, Zhang Y, Shi X, Liu L, Yao R
Frontiers in genetics 2021;12:722132

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The Downregulation of eIF3a Contributes to Vemurafenib Resistance in Melanoma by Activating ERK via PPP2R1B.

Jiang SL, Wang ZB, Zhu T, Jiang T, Fei JF, Liu C, Luo C, Cheng Y, Liu ZQ
Frontiers in pharmacology 2021;12:720619

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Inhibition of the Inflammasome Activity of NLRP3 Attenuates HDM-Induced Allergic Asthma.

Ma M, Li G, Qi M, Jiang W, Zhou R
Frontiers in immunology 2021;12:718779

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Exploring the Critical Components and Therapeutic Mechanisms of Perilla frutescens L. in the Treatment of Chronic Kidney Disease via Network Pharmacology.

Yong C, Zhang Z, Huang G, Yang Y, Zhu Y, Qian L, Tian F, Liu L, Wu Q, Xu Z, Chen C, Zhao J, Gao K, Zhou E
Frontiers in pharmacology 2021;12:717744

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Weighted Gene Co-Expression Network Analysis Identifies ANGPTL4 as a Key Regulator in Diabetic Cardiomyopathy via FAK/SIRT3/ROS Pathway in Cardiomyocyte.

Dai L, Xie Y, Zhang W, Zhong X, Wang M, Jiang H, He Z, Liu X, Zeng H, Wang H
Frontiers in endocrinology 2021;12:705154

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Edaravone Plays Protective Effects on LPS-Induced Microglia by Switching M1/M2 Phenotypes and Regulating NLRP3 Inflammasome Activation.

Li J, Dai X, Zhou L, Li X, Pan D
Frontiers in pharmacology 2021;12:691773

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Novel Pyrazolo[3,4-b] Pyridine Derivative (HLQ2g) Attenuates Hypoxic Pulmonary Hypertension via Restoring cGKI Expression and BMP Signaling Pathway.

Li L, Yin M, Hu L, Tian X, He X, Zhao C, Li Y, Li Q, Li X
Frontiers in pharmacology 2021;12:691405

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miR-25 Regulates Gastric Cancer Cell Growth and Apoptosis by Targeting EGR2.

Yang L, Li L, Chang P, Wei M, Chen J, Zhu C, Jia J
Frontiers in genetics 2021;12:690196

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An Escherichia coli Effector Protein EspF May Induce Host DNA Damage via Interaction With SMC1.

Fu M, Liang S, Wu J, Hua Y, Chen H, Zhang Z, Liu J, Li X, Zhang B, Zhao W, Wan C
Frontiers in microbiology 2021;12:682064

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Lidocaine Promoted Ferroptosis by Targeting miR-382-5p /SLC7A11 Axis in Ovarian and Breast Cancer.

Sun D, Li YC, Zhang XY
Frontiers in pharmacology 2021;12:681223

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Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke.

Xu ZQ, Zhang JJ, Kong N, Zhang GY, Ke P, Han T, Su DF, Liu C
Frontiers in pharmacology 2021;12:676589

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c-Myc Upregulated by High Glucose Inhibits HaCaT Differentiation by S100A6 Transcriptional Activation.

Zhang J, Yang P, Liu D, Gao M, Wang J, Wang X, Liu Y, Zhang X
Frontiers in endocrinology 2021;12:676403

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High Mobility Group Box 1 (HMGB1) Induces Toll-Like Receptor 4-Mediated Production of the Immunosuppressive Protein Galectin-9 in Human Cancer Cells.

Teo Hansen Selnø A, Schlichtner S, Yasinska IM, Sakhnevych SS, Fiedler W, Wellbrock J, Berger SM, Klenova E, Gibbs BF, Fasler-Kan E, Sumbayev VV
Frontiers in immunology 2021;12:675731

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Effects of Sodium Ferulate on Cardiac Hypertrophy Are via the CaSR-Mediated Signaling Pathway.

Chen P, Wen Z, Shi W, Li Z, Chen X, Gao Y, Xu S, Gong Q, Deng J
Frontiers in pharmacology 2021;12:674570

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SARS-CoV-2 Membrane Protein Inhibits Type I Interferon Production Through Ubiquitin-Mediated Degradation of TBK1.

Sui L, Zhao Y, Wang W, Wu P, Wang Z, Yu Y, Hou Z, Tan G, Liu Q
Frontiers in immunology 2021;12:662989

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Astragaloside IV Inhibits Galactose-Deficient IgA1 Secretion via miR-98-5p in Pediatric IgA Nephropathy.

Liu C, Li X, Shuai L, Dang X, Peng F, Zhao M, Xiong S, Liu Y, He Q
Frontiers in pharmacology 2021;12:658236

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Circ_0040039 May Aggravate Intervertebral Disk Degeneration by Regulating the MiR-874-3p-ESR1 Pathway.

Li Y, Wang X, Xu H, Li G, Huo Z, Du L, Zhang K, Shen L, Li H, Xu B
Frontiers in genetics 2021;12:656759

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A New Chalcone Derivative C49 Reverses Doxorubicin Resistance in MCF-7/DOX Cells by Inhibiting P-Glycoprotein Expression.

Wang T, Dong J, Yuan X, Wen H, Wu L, Liu J, Sui H, Deng W
Frontiers in pharmacology 2021;12:653306

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Nicotine Causes Mitochondrial Dynamics Imbalance and Apoptosis Through ROS Mediated Mitophagy Impairment in Cardiomyocytes.

Meng TT, Wang W, Meng FL, Wang SY, Wu HH, Chen JM, Zheng Y, Wang GX, Zhang MX, Li Y, Su GH
Frontiers in physiology 2021;12:650055

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Quercetin Attenuates Trauma-Induced Heterotopic Ossification by Tuning Immune Cell Infiltration and Related Inflammatory Insult.

Li J, Sun Z, Luo G, Wang S, Cui H, Yao Z, Xiong H, He Y, Qian Y, Fan C
Frontiers in immunology 2021;12:649285

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TOX Acts as a Tumor Suppressor by Inhibiting mTOR Signaling in Colorectal Cancer.

Yang M, Huang Q, Li C, Jiang Z, Sun J, Wang Z, Liang R, Li D, Li B, Zhao H
Frontiers in immunology 2021;12:647540

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Identification of a RAD52 Inhibitor Inducing Synthetic Lethality in BRCA2-Deficient Cancer Cells.

Yang Q, Li Y, Sun R, Li J
Frontiers in pharmacology 2021;12:637825

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BYHWD Alleviates Inflammatory Response by NIK-Mediated Repression of the Noncanonical NF-κB Pathway During ICH Recovery.

Xiao W, He Z, Luo W, Feng D, Wang Y, Tang T, Yang A, Luo J
Frontiers in pharmacology 2021;12:632407

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Increased Angiogenin Expression Correlates With Radiation Resistance and Predicts Poor Survival for Patients With Nasopharyngeal Carcinoma.

Guo SS, Liang YJ, Liu LT, Chen QY, Wen YF, Liu SL, Sun XS, Tang QN, Li XY, Mai HQ, Tang LQ
Frontiers in pharmacology 2021;12:627935

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Meteorin-Like Ameliorates β Cell Function by Inhibiting β Cell Apoptosis of and Promoting β Cell Proliferation via Activating the WNT/β-Catenin Pathway.

Hu W, Wang R, Sun B
Frontiers in pharmacology 2021;12:627147

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Duck Hepatitis A Virus Type 1 Induces eIF2α Phosphorylation-Dependent Cellular Translation Shutoff via PERK/GCN2.

Liu Y, Cheng A, Wang M, Mao S, Ou X, Yang Q, Wu Y, Gao Q, Liu M, Zhang S, Huang J, Jia R, Zhu D, Chen S, Zhao X, Yu Y, Liu Y, Zhang L, Tian B, Pan L
Frontiers in microbiology 2021;12:624540

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In Vivo Inhibition of MicroRNA-326 in a NOD.H-2(h4) Mouse Model of Autoimmune Thyroiditis.

Zhao N, Wang Z, Cui X, Wang S, Fan C, Li Y, Shan Z, Teng W
Frontiers in immunology 2021;12:620916

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IR-61 Improves Voiding Function via Mitochondrial Protection in Diabetic Rats.

Wang J, Dai L, Yue X, Shen C, Li T, Long L, Zhi Y, Wang Y, Shen G, Shi C, Liu Y, Fang Q, Li W
Frontiers in pharmacology 2021;12:608637

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Bortezomib Sustains T Cell Function by Inducing miR-155-Mediated Downregulation of SOCS1 and SHIP1.

Renrick AN, Thounaojam MC, de Aquino MTP, Chaudhuri E, Pandhare J, Dash C, Shanker A
Frontiers in immunology 2021;12:607044

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Inhibition of Shear-Induced Platelet Aggregation by Xueshuantong via Targeting Piezo1 Channel-Mediated Ca(2+) Signaling Pathway.

Liu L, Zhang Q, Xiao S, Sun Z, Ding S, Chen Y, Wang L, Yin X, Liao F, Jiang LH, Xue M, You Y
Frontiers in pharmacology 2021;12:606245

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SFTSV Infection Induced Interleukin-1β Secretion Through NLRP3 Inflammasome Activation.

Liu JW, Chu M, Jiao YJ, Zhou CM, Qi R, Yu XJ
Frontiers in immunology 2021;12:595140

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PHB2 promotes tumorigenesis via RACK1 in non-small cell lung cancer.

Wu B, Chang N, Xi H, Xiong J, Zhou Y, Wu Y, Wu S, Wang N, Yi H, Song Y, Chen L, Zhang J
Theranostics 2021;11(7):3150-3166

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Necroptosis pathway blockage attenuates PFKFB3 inhibitor-induced cell viability loss and genome instability in colorectal cancer cells.

Yan S, Li Q, Zhang D, Wang X, Xu Y, Zhang C, Guo D, Bao Y
American journal of cancer research 2021;11(5):2062-2080

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Targeting of glioma stem-like cells with a parthenolide derivative ACT001 through inhibition of AEBP1/PI3K/AKT signaling.

Hou Y, Sun B, Liu W, Yu B, Shi Q, Luo F, Bai Y, Feng H
Theranostics 2021;11(2):555-566

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Local administration of liposomal-based Srpx2 gene therapy reverses pulmonary fibrosis by blockading fibroblast-to-myofibroblast transition.

Wang Q, Liu J, Hu Y, Pan T, Xu Y, Yu J, Xiong W, Zhou Q, Wang Y
Theranostics 2021;11(14):7110-7125

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KAT6A, a novel regulator of β-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1.

Liu W, Zhan Z, Zhang M, Sun B, Shi Q, Luo F, Zhang M, Zhang W, Hou Y, Xiao X, Li Y, Feng H
Theranostics 2021;11(13):6278-6292

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Aurka loss in CD19(+) B cells promotes megakaryocytopoiesis via IL-6/STAT3 signaling-mediated thrombopoietin production.

Chen X, Wang C, Sun N, Pan S, Li R, Li X, Zhao J, Tong H, Tang Y, Han J, Qiao J, Qiu H, Wang H, Yang J, Ikezoe T
Theranostics 2021;11(10):4655-4671

---

Ese-3 contributes to colon cancer progression by downregulating EHD2 and transactivating INPP4B.

Li J, Yang J, Hua L, Wang R, Li H, Zhang C, Zhang H, Li S, Zhu L, Su H
American journal of cancer research 2021;11(1):92-107

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Cardiac telocytes inhibit cardiac microvascular endothelial cell apoptosis through exosomal miRNA-21-5p-targeted cdip1 silencing to improve angiogenesis following myocardial infarction.

Liao Z, Chen Y, Duan C, Zhu K, Huang R, Zhao H, Hintze M, Pu Q, Yuan Z, Lv L, Chen H, Lai B, Feng S, Qi X, Cai D
Theranostics 2021;11(1):268-291

---

Deferoxamine Counteracts Cisplatin Resistance in A549 Lung Adenocarcinoma Cells by Increasing Vulnerability to Glutamine Deprivation-Induced Cell Death.

Liu WJ, Pan PY, Sun Y, Wang JB, Zhou H, Xie X, Duan ZY, Dong HY, Chen WN, Zhang LD, Wang C
Frontiers in oncology 2021;11:794735

---

Phospholipid Phosphatase 4 as a Driver of Malignant Glioma and Pancreatic Adenocarcinoma.

Tian W, Wang P, Wang Z, Qi H, Dong J, Wang H
Frontiers in oncology 2021;11:790676

---

Modulated TRPC1 Expression Predicts Sensitivity of Breast Cancer to Doxorubicin and Magnetic Field Therapy: Segue Towards a Precision Medicine Approach.

Tai YK, Chan KKW, Fong CHH, Ramanan S, Yap JLY, Yin JN, Yip YS, Tan WR, Koh APF, Tan NS, Chan CW, Huang RYJ, Li JZ, Fröhlich J, Franco-Obregón A
Frontiers in oncology 2021;11:783803

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ITGA5 Predicts Dual-Drug Resistance to Temozolomide and Bevacizumab in Glioma.

Shi Y, Wu M, Liu Y, Hu L, Wu H, Xie L, Liu Z, Wu A, Chen L, Xu C
Frontiers in oncology 2021;11:769592

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Prognostic Value and Correlation With Tumor Immune Infiltration of a Novel Metabolism-Related Gene Signature in Pancreatic Cancer.

Chen H, Zu F, Zeng T, Chen Z, Wei J, Liu P, Li Z, Zhou L, Wang H, Tan H, Tan X
Frontiers in oncology 2021;11:757791

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Autophagy-Induced HDAC6 Activity During Hypoxia Regulates Mitochondrial Energy Metabolism Through the β-Catenin/COUP-TFII Axis in Hepatocellular Carcinoma Cells.

Yan X, Qu X, Liu B, Zhao Y, Xu L, Yu S, Wang J, Wang L, Su J
Frontiers in oncology 2021;11:742460

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Purified Vitexin Compound 1 Serves as a Promising Antineoplastic Agent in Ovarian Cancer.

Ma K, Wang K, Zhou Y, Liu N, Guo W, Qi J, Hu Z, Su S, Tang P, Zhou X
Frontiers in oncology 2021;11:734708

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Identification of Glycolysis-Related lncRNAs and the Novel lncRNA WAC-AS1 Promotes Glycolysis and Tumor Progression in Hepatocellular Carcinoma.

Xia X, Zhang H, Xia P, Zhu Y, Liu J, Xu K, Yuan Y
Frontiers in oncology 2021;11:733595

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Honokiol Suppresses Perineural Invasion of Pancreatic Cancer by Inhibiting SMAD2/3 Signaling.

Qin T, Li J, Xiao Y, Wang X, Gong M, Wang Q, Zhu Z, Zhang S, Zhang W, Cao F, Han L, Wang Z, Ma Q, Sha H
Frontiers in oncology 2021;11:728583

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The Anti-Colon Cancer Effects of Essential Oil of Curcuma phaeocaulis Through Tumour Vessel Normalisation.

Feng Y, Deng L, Guo H, Zhao Y, Peng F, Wang G, Yu C
Frontiers in oncology 2021;11:728464

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Downregulation of miR-142a Contributes to the Enhanced Anti-Apoptotic Ability of Murine Chronic Myelogenous Leukemia Cells.

Chen Z, Xie Y, Liu D, Liu P, Li F, Zhang Z, Zhang M, Wang X, Zhang Y, Sun X, Huang Q
Frontiers in oncology 2021;11:718731

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Cystatin-B Negatively Regulates the Malignant Characteristics of Oral Squamous Cell Carcinoma Possibly Via the Epithelium Proliferation/Differentiation Program.

Xu TT, Zeng XW, Wang XH, Yang LX, Luo G, Yu T
Frontiers in oncology 2021;11:707066

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NEK7 Promotes Pancreatic Cancer Progression And Its Expression Is Correlated With Poor Prognosis.

Yan Z, Qu J, Li Z, Yi J, Su Y, Lin Q, Yu G, Lin Z, Yin W, Lu F, Liu J
Frontiers in oncology 2021;11:705797

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Transcriptomic Analyses of the Adenoma-Carcinoma Sequence Identify Hallmarks Associated With the Onset of Colorectal Cancer.

Hong Q, Li B, Cai X, Lv Z, Cai S, Zhong Y, Wen B
Frontiers in oncology 2021;11:704531

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The EIF4A3/CASC2/RORA Feedback Loop Regulates the Aggressive Phenotype in Glioblastomas.

Zhao J, Jiang Y, Chen L, Ma Y, Zhang H, Zhou J, Li H, Jing Z
Frontiers in oncology 2021;11:699933

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Aeromonas sobria Induces Proinflammatory Cytokines Production in Mouse Macrophages via Activating NLRP3 Inflammasome Signaling Pathways.

Zhang W, Li Z, Yang H, Wang G, Liu G, Wang Y, Bello BK, Zhao P, Liang W, Dong J
Frontiers in cellular and infection microbiology 2021;11:691445

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Transcriptomic Analyses Reveal B-Cell Translocation Gene 2 as a Potential Therapeutic Target in Ovarian Cancer.

Wang J, Li H, Wang L, Zhang J, Li M, Qiao L, Zhang J, Liu L, Zhang C, Gao J, Li W
Frontiers in oncology 2021;11:681250

---

The RNA-Binding Protein NELFE Promotes Gastric Cancer Growth and Metastasis Through E2F2.

Chen C, Zheng Q, Pan S, Chen W, Huang J, Cao Y, Tu Y, Li Z, Yu C, Jie Z
Frontiers in oncology 2021;11:677111

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Long Non-Coding RNA LINC00467 Correlates to Poor Prognosis and Aggressiveness of Breast Cancer.

Zhang Y, Sun Y, Ding L, Shi W, Ding K, Zhu Y
Frontiers in oncology 2021;11:643394

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N6-Methyladenosine Modification of LncRNA DUXAP9 Promotes Renal Cancer Cells Proliferation and Motility by Activating the PI3K/AKT Signaling Pathway.

Tan L, Tang Y, Li H, Li P, Ye Y, Cen J, Gui C, Luo J, Cao J, Wei J
Frontiers in oncology 2021;11:641833

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Downregulation of GLYAT Facilitates Tumor Growth and Metastasis and Poor Clinical Outcomes Through the PI3K/AKT/Snail Pathway in Human Breast Cancer.

Tian X, Wu L, Jiang M, Zhang Z, Wu R, Miao J, Liu C, Gao S
Frontiers in oncology 2021;11:641399

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MiR-454-3p Promotes Oxaliplatin Resistance by Targeting PTEN in Colorectal Cancer.

Qian XL, Zhou F, Xu S, Jiang J, Chen ZP, Wang SK, Zuo Y, Ni C
Frontiers in oncology 2021;11:638537

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Asparagine Synthetase-Mediated l-Asparagine Metabolism Disorder Promotes the Perineural Invasion of Oral Squamous Cell Carcinoma.

Fu Y, Ding L, Yang X, Ding Z, Huang X, Zhang L, Chen S, Hu Q, Ni Y
Frontiers in oncology 2021;11:637226

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Discovering and Characterizing of Survivin Dominant Negative Mutants With Stronger Pro-apoptotic Activity on Cancer Cells and CSCs.

Guo W, Ma X, Fu Y, Liu C, Liu Q, Hu F, Miao H, Zhang T, Liu Y, Han MH, You F, Yang Y, Zheng W
Frontiers in oncology 2021;11:635233

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HOXA5 Is Recognized as a Prognostic-Related Biomarker and Promotes Glioma Progression Through Affecting Cell Cycle.

Ding F, Chen P, Bie P, Piao W, Cheng Q
Frontiers in oncology 2021;11:633430

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TFEB Promotes Prostate Cancer Progression via Regulating ABCA2-Dependent Lysosomal Biogenesis.

Zhu X, Zhuo Y, Wu S, Chen Y, Ye J, Deng Y, Feng Y, Liu R, Cai S, Zou Z, Wang B, Wu CL, Zeng G, Zhong W
Frontiers in oncology 2021;11:632524

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Identification of Hub Genes Associated With Sensitivity of 5-Fluorouracil Based Chemotherapy for Colorectal Cancer by Integrated Bioinformatics Analysis.

Wang Y, Wei Q, Chen Y, Long S, Yao Y, Fu K
Frontiers in oncology 2021;11:604315

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IFN-γ facilitates liver fibrogenesis by CD161(+)CD4(+) T cells through a regenerative IL-23/IL-17 axis in chronic hepatitis B virus infection.

Li J, Cheng L, Jia H, Liu C, Wang S, Liu Y, Shen Y, Wu S, Meng F, Zheng B, Yang C, Jiang W
Clinical & translational immunology 2021;10(11):e1353

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Epigallocatechin-3-gallate inhibits proliferation and triggers apoptosis in colon cancer via the hedgehog/phosphoinositide 3-kinase pathways.

Ding F, Yang S
Canadian journal of physiology and pharmacology 2021 Sep;99(9):910-920

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SARS-CoV-2 ORF9b antagonizes type I and III interferons by targeting multiple components of the RIG-I/MDA-5-MAVS, TLR3-TRIF, and cGAS-STING signaling pathways.

Han L, Zhuang MW, Deng J, Zheng Y, Zhang J, Nan ML, Zhang XJ, Gao C, Wang PH
Journal of medical virology 2021 Sep;93(9):5376-5389

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Subicular Caspase-1 Contributes to Pharmacoresistance in Temporal Lobe Epilepsy.

Xu C, Zhang S, Gong Y, Nao J, Shen Y, Tan B, Xu S, Cui S, Ruan Y, Wang S, Wang Y, Chen Z
Annals of neurology 2021 Sep;90(3):377-390

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Yangonin modulates lipid homeostasis, ameliorates cholestasis and cellular senescence in alcoholic liver disease via activating nuclear receptor FXR.

Kong L, Dong R, Huang K, Wang X, Wang D, Yue N, Wang C, Sun P, Gu J, Luo H, Liu K, Wu J, Sun H, Meng Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Sep;90:153629

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TLR2 inhibition ameliorates the amplification effect of LPS on lipid accumulation and lipotoxicity in hepatic cells.

Zhang L, Xie Z, Yu H, Du H, Wang X, Cai J, Qiu Y, Chen R, Jiang X, Liu Z, Li Y, Chen T
Annals of translational medicine 2021 Sep;9(18):1429

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Spindle and kinetochore-associated complex subunit 3 (SKA3) promotes stem cell-like properties of hepatocellular carcinoma cells through activating Notch signaling pathway.

Bai S, Chen W, Zheng M, Wang X, Peng W, Zhao Y, Wang Y, Xiong S, Cheng B
Annals of translational medicine 2021 Sep;9(17):1361

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Actin-binding protein, IQGAP1, regulates LPS-induced RPMVECs hyperpermeability and ICAM-1 upregulation via Rap1/Src signalling pathway.

Zhang N, Wang G, Sun G
Cellular signalling 2021 Sep;85:110067

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HOXA5 induces M2 macrophage polarization to attenuate carotid atherosclerosis by activating MED1.

Jing Y, Gao B, Han Z, Xin S
IUBMB life 2021 Sep;73(9):1142-1152

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Homoharringtonine inhibits the progression of hepatocellular carcinoma by suppressing the PI3K/AKT/GSK3β/Slug signaling pathway.

Liu HY, Dong TX, Li ZZ, Li TT, Jiang J, Zhu MW, An TT, Chen YD, Yang XH
Neoplasma 2021 Sep;68(5):924-937

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AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence.

Lee S, Karki R, Wang Y, Nguyen LN, Kalathur RC, Kanneganti TD
Nature 2021 Sep;597(7876):415-419

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Disruption of Circadian Clocks Promotes Progression of Alzheimer's Disease in Diabetic Mice.

Huang J, Peng X, Fan R, Dong K, Shi X, Zhang S, Yu X, Yang Y
Molecular neurobiology 2021 Sep;58(9):4404-4412

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Postconditioning with Sevoflurane or Propofol Alleviates Lipopolysaccharide-Induced Neuroinflammation but Exerts Dissimilar Effects on the NR2B Subunit and Cognition.

Liu H, Chen B, Guo B, Deng X, Wang B, Dou X
Molecular neurobiology 2021 Sep;58(9):4251-4267

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Melatonin and doxorubicin synergistically enhance apoptosis via autophagy-dependent reduction of AMPKα1 transcription in human breast cancer cells.

Tran QH, Hoang DH, Song M, Choe W, Kang I, Kim SS, Ha J
Experimental & molecular medicine 2021 Sep;53(9):1413-1422

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Bruton's tyrosine kinase regulates macrophage‑induced inflammation in the diabetic kidney via NLRP3 inflammasome activation.

Zhao J, Chen J, Li YY, Xia LL, Wu YG
International journal of molecular medicine 2021 Sep;48(3)

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Environmental Microcystin exposure in underlying NAFLD-induced exacerbation of neuroinflammation, blood-brain barrier dysfunction, and neurodegeneration are NLRP3 and S100B dependent.

Mondal A, Saha P, Bose D, Chatterjee S, Seth RK, Xiao S, Porter DE, Brooks BW, Scott GI, Nagarkatti M, Nagarkatti P, Chatterjee S
Toxicology 2021 Sep;461:152901

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Spata2 Knockdown Exacerbates Brain Inflammation via NF-κB/P38MAPK Signaling and NLRP3 Inflammasome Activation in Cerebral Ischemia/Reperfusion Rats.

Ren Y, Jiang J, Jiang W, Zhou X, Lu W, Wang J, Luo Y
Neurochemical research 2021 Sep;46(9):2262-2275

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Long noncoding RNA ANRIL knockdown attenuates neuroinflammation following ischemic stroke via suppressing the expression of NF-κB in vitro and in vivo.

Deng L, Guo Y, Liu J, Chen S, Wang X, Zhao H, Zuo T, Hu Q, Dong Z
Neurological research 2021 Sep;43(9):767-777

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KDELR2 promotes breast cancer proliferation via HDAC3-mediated cell cycle progression.

Wei H, Ma W, Lu X, Liu H, Lin K, Wang Y, Ye Z, Sun L, Huang Z, Pan T, Zhou Z, Cheng EY, Zhang H, Gao P, Zhong X
Cancer communications (London, England) 2021 Sep;41(9):904-920

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Gastrodin protects against high glucose-induced cardiomyocyte toxicity via GSK-3β-mediated nuclear translocation of Nrf2.

Dong Z, Bian L, Wang YL, Sun LM
Human & experimental toxicology 2021 Sep;40(9):1584-1597

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An Antioxidant Sesquiterpene Inhibits Osteoclastogenesis Via Blocking IPMK/TRAF6 and Counteracts OVX-Induced Osteoporosis in Mice.

Wang S, Ma Q, Xie Z, Shen Y, Zheng B, Jiang C, Yuan P, An Q, Fan S, Jie Z
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2021 Sep;36(9):1850-1865

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Long non-coding RNA DUXAP9 promotes hepatocellular carcinoma cell stemness via directly interacting with sox9.

Zeng R, Wang C, Wang W, Wang S
Environmental toxicology 2021 Sep;36(9):1793-1801

---

Compound essential oils relieve oxidative stress caused by PM(2) (.5) exposure by inhibiting autophagy through the AMPK/mTOR pathway.

Ren F, Xu X, Xu J, Mei Y, Zhang J, Wang X, Li F
Environmental toxicology 2021 Sep;36(9):1765-1774

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CTR9-mediated JAK2/STAT3 pathway promotes the proliferation, migration, and invasion of human glioma cells.

Xu Y, Chen J, He G, Zhang Y
Journal of clinical laboratory analysis 2021 Sep;35(9):e23943

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MiR-100-5p regulates cardiac hypertrophy through activation of autophagy by targeting mTOR.

Zeng J, Wang L, Zhao J, Zheng Z, Peng J, Zhang W, Wen T, Nie J, Ding L, Yi D
Human cell 2021 Sep;34(5):1388-1397

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Bone marrow mesenchymal stem cell-derived exosomes induce the Th17/Treg imbalance in immune thrombocytopenia through miR-146a-5p/IRAK1 axis.

He Y, Ji D, Lu W, Li F, Huang X, Huang R, Chen G
Human cell 2021 Sep;34(5):1360-1374

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Bovine viral diarrhea virus NS4B protein interacts with 2CARD of MDA5 domain and negatively regulates the RLR-mediated IFN-β production.

Shan Y, Tong Z, Jinzhu M, Yu L, Zecai Z, Chenhua W, Wenjing H, Siyu L, Nannan C, Siyu S, Tongtong B, Jiang H, Biaohui B, Xin J, Yulong Z, Zhanbo Z
Virus research 2021 Sep;302:198471

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Docosahexaenoic acid activates the Nrf2 signaling pathway to alleviate impairment of spleen cellular immunity in intrauterine growth restricted rat pups.

Jiang W, Wan L, Chen P, Lu W
Saudi journal of biological sciences 2021 Sep;28(9):4987-4993

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Cinnabar protects serum-nutrient starvation induced apoptosis by improving intracellular oxidative stress and inhibiting the expression of CHOP and PERK.

Ma HH, Ding YN, Wang A, Li X, Wang Y, Shi FG, Lu YF
Biochemistry and biophysics reports 2021 Sep;27:101055

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miR-29c-3p regulates TET2 expression and inhibits autophagy process in Parkinson's disease models.

Wang R, Yao J, Gong F, Chen S, He Y, Hu C, Li C
Genes to cells : devoted to molecular & cellular mechanisms 2021 Sep;26(9):684-697

---

DNM3OS regulates GAPDH expression and influences the molecular pathogenesis of Huntington's disease.

Dong X, Cong S
Journal of cellular and molecular medicine 2021 Sep;25(18):9066-9071

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Exogenous H(2) S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.

Zhang L, Jiang X, Liu N, Li M, Kang J, Chen L, Tang J, Dong S, Lu F, Zhang W
Journal of cellular and molecular medicine 2021 Sep;25(17):8201-8214

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Expression of TCF3 in Wilms' tumor and its regulatory role in kidney tumor cell viability, migration and apoptosis in vitro.

Zhou N, Yan B, Ma J, Jiang H, Li L, Tang H, Ji F, Yao Z
Molecular medicine reports 2021 Sep;24(3)

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Identification and validation of EPHX2 as a prognostic biomarker in hepatocellular carcinoma.

Zhan K, Bai Y, Liao S, Chen H, Kuang L, Luo Q, Lv L, Qiu L, Mei Z
Molecular medicine reports 2021 Sep;24(3)

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Salusin‑β participates in high glucose‑induced HK‑2 cell ferroptosis in a Nrf‑2‑dependent manner.

Wang WJ, Jiang X, Gao CC, Chen ZW
Molecular medicine reports 2021 Sep;24(3)

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Lack of Mof reduces acute liver injury by enhancing transcriptional activation of Igf1.

Wang M, Liu H, Zhang X, Zhao W, Li D, Xu C, Wu Z, Xie F, Li X
Journal of cellular physiology 2021 Sep;236(9):6559-6570

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PKC-β/Alox5 axis activation promotes Bcr-Abl-independent TKI-resistance in chronic myeloid leukemia.

Ma D, Liu P, Wang P, Zhou Z, Fang Q, Wang J
Journal of cellular physiology 2021 Sep;236(9):6312-6327

---

Propofol inhibited gastric cancer proliferation via the hsa-miR-328-3p/STAT3 pathway.

Bai ZM, Li XF, Yang Y, Yang YF, Lv DR, Tang LL
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2021 Sep;23(9):1866-1873

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The piRNA pathway is essential for generating functional oocytes in golden hamsters.

Zhang H, Zhang F, Chen Q, Li M, Lv X, Xiao Y, Zhang Z, Hou L, Lai Y, Zhang Y, Zhang A, Gao S, Fu H, Xiao W, Zhou J, Diao F, Shi A, Su YQ, Zeng W, Wu L, Li J
Nature cell biology 2021 Sep;23(9):1013-1022

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RNA N(6) -methyladenosine modification suppresses replication of rice black streaked dwarf virus and is associated with virus persistence in its insect vector.

Tian S, Wu N, Zhang L, Wang X
Molecular plant pathology 2021 Sep;22(9):1070-1081

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Autophagy promotes invadopodia formation in human ovarian cancer cells via the p62-extracellular signal-regulated kinase 1/2 pathway.

Zhou Z, Zhao J, Liu Y, Yan X, Sun H, Xia M, Su J
Experimental and therapeutic medicine 2021 Sep;22(3):952

---

Low-dose repeated exposure to chemical surfactant impairs corneal epithelium: When personal cleaning products entering the eye.

Wu J, Wu T, Zheng S, Huang Y, Wang L
Experimental eye research 2021 Sep;210:108696

---

Hsa_circ_0006232 promotes laryngeal squamous cell cancer progression through FUS-mediated EZH2 stabilization.

Wu T, Wang G, Zeng X, Sun Z, Li S, Wang W, Yu B
Cell cycle (Georgetown, Tex.) 2021 Sep;20(18):1799-1811

---

Total Flavonoids of Engelhardia roxburghiana Wall. Leaves Alleviated Foam Cells Formation through AKT/mTOR-Mediated Autophagy in the Progression of Atherosclerosis.

Wei J, Huang L, Li D, He J, Li Y, He F, Fang W, Wei G
Chemistry & biodiversity 2021 Sep;18(9):e2100308

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High mobility group box 1 mediates inflammatory response of astrocytes via cyclooxygenase 2/prostaglandin E2 signaling following spinal cord injury.

Song HH, Song TC, Yang T, Sun CS, He BQ, Li H, Wang YJ, Li Y, Wu H, Hu YM, Wang YJ
Neural regeneration research 2021 Sep;16(9):1848-1855

---

Ruyiping extract reduces lung metastasis in triple negative breast cancer by regulating macrophage polarization.

Yang R, Xie Y, Li Q, Ye Y, Shi Y, Zhao X, Wu C, Xu Y, Wang R, Zhang Y, Yang X, Han X, Liu S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Sep;141:111883

---

Quadruple-editing of the MAPK and PI3K pathways effectively blocks the progression of KRAS-mutated colorectal cancer cells.

Wang Z, Kang B, Gao Q, Huang L, Di J, Fan Y, Yu J, Jiang B, Gao F, Wang D, Sun H, Gu Y, Li J, Su X
Cancer science 2021 Sep;112(9):3895-3910

---

METTL14 promotes glomerular endothelial cell injury and diabetic nephropathy via m6A modification of α-klotho.

Li M, Deng L, Xu G
Molecular medicine (Cambridge, Mass.) 2021 Sep 9;27(1):106

---

Genomic and epigenomic evolution of acquired resistance to combination therapy in esophageal squamous cell carcinoma.

Min Q, Wang Y, Wu Q, Li X, Teng H, Fan J, Cao Y, Fan P, Zhan Q
JCI insight 2021 Sep 8;6(17)

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Viral targeting of glioblastoma stem cells with patient-specific genetic and post-translational p53 deregulations.

Gil-Ranedo J, Gallego-García C, Almendral JM
Cell reports 2021 Sep 7;36(10):109673

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A pair of long intergenic non-coding RNA LINC00887 variants act antagonistically to control Carbonic Anhydrase IX transcription upon hypoxia in tongue squamous carcinoma progression.

Shen T, Xia W, Min S, Yang Z, Cheng L, Wang W, Zhan Q, Shao F, Zhang X, Wang Z, Zhang Y, Shen G, Zhang H, Wu LL, Yu GY, Kong QP, Wang X
BMC biology 2021 Sep 7;19(1):192

---

Cannabidiol Effectively Promoted Cell Death in Bladder Cancer and the Improved Intravesical Adhesion Drugs Delivery Strategy Could Be Better Used for Treatment.

Chen S, Deng C, Zheng W, Li S, Liu Y, Zhang T, Zhang C, Fu Y, Miao H, Ren F, Ma X
Pharmaceutics 2021 Sep 7;13(9)

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ACLY ubiquitination by CUL3-KLHL25 induces the reprogramming of fatty acid metabolism to facilitate iTreg differentiation.

Tian M, Hao F, Jin X, Sun X, Jiang Y, Wang Y, Li D, Chang T, Zou Y, Peng P, Xia C, Liu J, Li Y, Wang P, Feng Y, Wei M
eLife 2021 Sep 7;10

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Suppressors of cytokine signaling 1 protein in a regenerative model of the Gekko japonicus spinal cord.

He B, Wang W, Sun C, Yang T, Li H, Chen X, Liang H, Song H, Wang Y, Wang Y
Journal of integrative neuroscience 2021 Sep 30;20(3):585-594

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Stimulation of ROS Generation by Extract of Warburgia ugandensis Leading to G(0)/G(1) Cell Cycle Arrest and Antiproliferation in A549 Cells.

Zhang YL, Chen GL, Liu Y, Zhuang XC, Guo MQ
Antioxidants (Basel, Switzerland) 2021 Sep 30;10(10)

---

Identification and Characterization of Eimeria tenella Microneme Protein (EtMIC8).

Zhao N, Ming S, Sun L, Wang B, Li H, Zhang X, Zhao X
Microbiology spectrum 2021 Sep 3;9(1):e0022821

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HIF-1α/JMJD1A signaling regulates inflammation and oxidative stress following hyperglycemia and hypoxia-induced vascular cell injury.

Zhao M, Wang S, Zuo A, Zhang J, Wen W, Jiang W, Chen H, Liang D, Sun J, Wang M
Cellular & molecular biology letters 2021 Sep 3;26(1):40

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Adipose expression of CREB3L3 modulates body weight during obesity.

McCann MA, Li Y, Muñoz M, Gil V, Qiang G, Cordoba-Chacon J, Blüher M, Duncan S, Liew CW
Scientific reports 2021 Sep 29;11(1):19400

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Exosomal microRNA-588 from M2 polarized macrophages contributes to cisplatin resistance of gastric cancer cells.

Cui HY, Rong JS, Chen J, Guo J, Zhu JQ, Ruan M, Zuo RR, Zhang SS, Qi JM, Zhang BH
World journal of gastroenterology 2021 Sep 28;27(36):6079-6092

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Dual Inhibition of Endoplasmic Reticulum Stress and Oxidation Stress Manipulates the Polarization of Macrophages under Hypoxia to Sensitize Immunotherapy.

Jiang M, Li X, Zhang J, Lu Y, Shi Y, Zhu C, Liu Y, Qin B, Luo Z, Du Y, Luo L, Peng L, You J
ACS nano 2021 Sep 28;15(9):14522-14534

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Identification of genes and pathways leading to metastasis and poor prognosis in melanoma.

Zhang X, Wang W, Wang Y, Jiang G
Aging 2021 Sep 28;13(18):22474-22489

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The Ginsenoside Rg(1) Rescues Mitochondrial Disorders in Aristolochic Acid-Induced Nephropathic Mice.

Chou CK, Huang YS, Lin PY, Imai K, Chen SM, Lee JA
Life (Basel, Switzerland) 2021 Sep 27;11(10)

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Anti-osteosarcoma effect of antiserum against cross antigen TPD52 between osteosarcoma and Trichinella spiralis.

Yue TT, Zhang N, Li JH, Lu XY, Wang XC, Li X, Zhang HB, Cheng SQ, Wang BB, Gong PT, Zhang XC
Parasites & vectors 2021 Sep 26;14(1):498

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MEST promotes lung cancer invasion and metastasis by interacting with VCP to activate NF-κB signaling.

Wang Y, Zhang J, Li YJ, Yu NN, Liu WT, Liang JZ, Xu WW, Sun ZH, Li B, He QY
Journal of experimental & clinical cancer research : CR 2021 Sep 24;40(1):301

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Potent Inhibition of HIF1α and p300 Interaction by a Constrained Peptide Derived from CITED2.

Qin X, Chen H, Tu L, Ma Y, Liu N, Zhang H, Li D, Riedl B, Bierer D, Yin F, Li Z
Journal of medicinal chemistry 2021 Sep 23;64(18):13693-13703

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Discovery of a Potent Glutathione Peroxidase 4 Inhibitor as a Selective Ferroptosis Inducer.

Xu C, Xiao Z, Wang J, Lai H, Zhang T, Guan Z, Xia M, Chen M, Ren L, He Y, Gao Y, Zhao C
Journal of medicinal chemistry 2021 Sep 23;64(18):13312-13326

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Perinatal low-dose bisphenol AF exposure impairs synaptic plasticity and cognitive function of adult offspring in a sex-dependent manner.

Zhang C, Wu XC, Li S, Dou LJ, Zhou L, Wang FH, Ma K, Huang D, Pan Y, Gu JJ, Cao JY, Wang H, Hao JH
The Science of the total environment 2021 Sep 20;788:147918

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Genistein exhibits therapeutic potential for PCOS mice via the ER-Nrf2-Foxo1-ROS pathway.

Luo M, Zheng LW, Wang YS, Huang JC, Yang ZQ, Yue ZP, Guo B
Food & function 2021 Sep 20;12(18):8800-8811

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Isonicotinylation is a histone mark induced by the anti-tuberculosis first-line drug isoniazid.

Jiang Y, Li Y, Liu C, Zhang L, Lv D, Weng Y, Cheng Z, Chen X, Zhan J, Zhang H
Nature communications 2021 Sep 20;12(1):5548

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β-adrenergic receptor inhibition enhances oncolytic herpes virus propagation through STAT3 activation in gastric cancer.

Hu J, Lu R, Zhang Y, Li W, Hu Q, Chen C, Liu Z, Zhang W, Chen L, Xu R, Luo J, McLeod HL, He Y
Cell & bioscience 2021 Sep 20;11(1):174

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Ultramicronized Palmitoylethanolamide Inhibits NLRP3 Inflammasome Expression and Pro-Inflammatory Response Activated by SARS-CoV-2 Spike Protein in Cultured Murine Alveolar Macrophages.

Del Re A, Corpetti C, Pesce M, Seguella L, Steardo L, Palenca I, Rurgo S, De Conno B, Sarnelli G, Esposito G
Metabolites 2021 Sep 2;11(9)

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RIOK2 Inhibitor NSC139021 Exerts Anti-Tumor Effects on Glioblastoma via Inducing Skp2-Mediated Cell Cycle Arrest and Apoptosis.

Yu M, Hu X, Yan J, Wang Y, Lu F, Chang J
Biomedicines 2021 Sep 17;9(9)

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Lactobacillus johnsonii L531 Alleviates the Damage Caused by Salmonella Typhimurium via Inhibiting TLR4, NF-κB, and NLRP3 Inflammasome Signaling Pathways.

Chen S, Li Y, Chu B, Yuan L, Liu N, Zhu Y, Wang J
Microorganisms 2021 Sep 17;9(9)

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KIF15 upregulation promotes leiomyosarcoma cell growth via promoting USP15-mediated DEK deubiquitylation.

Ge W, Chen Y, Guo Y, Zhao D, Mu L, Zhang K, Zhuo W
Biochemical and biophysical research communications 2021 Sep 17;570:117-124

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UBE2S promotes the progression and Olaparib resistance of ovarian cancer through Wnt/β-catenin signaling pathway.

Hu W, Li M, Chen Y, Gu X
Journal of ovarian research 2021 Sep 17;14(1):121

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HSF1 is involved in suppressing A1 phenotype conversion of astrocytes following spinal cord injury in rats.

Li L, Li Y, He B, Li H, Ji H, Wang Y, Zhu Z, Hu Y, Zhou Y, Yang T, Sun C, Yuan Y, Wang Y
Journal of neuroinflammation 2021 Sep 16;18(1):205

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MiR-200c-3p promotes ox-LDL-induced endothelial to mesenchymal transition in human umbilical vein endothelial cells through SMAD7/YAP pathway.

Mao Y, Jiang L
The journal of physiological sciences : JPS 2021 Sep 15;71(1):30

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Harmine-inspired design and synthesis of benzo[d]imidazo[2,1-b]thiazole derivatives bearing 1,3,4-oxadiazole moiety as potential tumor suppressors.

Zhao T, Yang Y, Yang J, Cui Y, Cao Z, Zuo D, Zhai X
Bioorganic & medicinal chemistry 2021 Sep 15;46:116367

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Hypoxia increases KIAA1199/CEMIP expression and enhances cell migration in pancreatic cancer.

Oba T, Sato N, Adachi Y, Amaike T, Kudo Y, Koga A, Kohi S, Hirata K
Scientific reports 2021 Sep 14;11(1):18193

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Genetically variant human pluripotent stem cells selectively eliminate wild-type counterparts through YAP-mediated cell competition.

Price CJ, Stavish D, Gokhale PJ, Stevenson BA, Sargeant S, Lacey J, Rodriguez TA, Barbaric I
Developmental cell 2021 Sep 13;56(17):2455-2470.e10

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Ketamine ameliorates depressive-like behaviors in mice through increasing glucose uptake regulated by the ERK/GLUT3 signaling pathway.

Ouyang X, Wang Z, Luo M, Wang M, Liu X, Chen J, Feng J, Jia J, Wang X
Scientific reports 2021 Sep 13;11(1):18181

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A standardized extract of Asparagus officinalis stem improves HSP70-mediated redox balance and cell functions in bovine cumulus-granulosa cells.

Ho KT, Homma K, Takanari J, Bai H, Kawahara M, Nguyen KTK, Takahashi M
Scientific reports 2021 Sep 13;11(1):18175

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2,5-dimethyl celecoxib induces apoptosis and autophagy via activation of ROS/JNK axis in nasopharyngeal carcinoma cells.

Tan T, Fu X, Qu J, Zhang M, Chen H, Wang Y, Wang B, Li J, Liu J, Liu P
Aging 2021 Sep 12;13(17):21483-21496

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Defining the Cholesterol Lowering Mechanism of Bergamot (Citrus bergamia) Extract in HepG2 and Caco-2 Cells.

Huang Y, Tocmo R, Nauman MC, Haughan MA, Johnson JJ
Nutrients 2021 Sep 10;13(9)

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Targeting chromosome trisomy for chromosome editing.

Abe T, Suzuki Y, Ikeya T, Hirota K
Scientific reports 2021 Sep 10;11(1):18054

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Baicalein Enhances the Effect of Acarbose on the Improvement of Nonalcoholic Fatty Liver Disease Associated with Prediabetes via the Inhibition of De Novo Lipogenesis.

Xing Y, Ren X, Li X, Sui L, Shi X, Sun Y, Quan C, Xiu Z, Dong Y
Journal of agricultural and food chemistry 2021 Sep 1;69(34):9822-9836

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H(2)S alleviates aortic aneurysm and dissection: Crosstalk between transforming growth factor 1 signaling and NLRP3 inflammasome.

Cui J, Xu G, Bian F
International journal of cardiology 2021 Sep 1;338:215-225

---

Silica nanoparticles inhibiting the differentiation of round spermatid and chromatin remodeling of haploid period via MIWI in mice.

Liu J, Li X, Zhou G, Zhang Y, Sang Y, Wang J, Li Y, Ge W, Sun Z, Zhou X
Environmental pollution (Barking, Essex : 1987) 2021 Sep 1;284:117446

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LncAY controls BMI1 expression and activates BMI1/Wnt/β-catenin signaling axis in hepatocellular carcinoma.

Chen MH, Fu LS, Zhang F, Yang Y, Wu XZ
Life sciences 2021 Sep 1;280:119748

---

Sitagliptin attenuates endothelial dysfunction independent of its blood glucose controlling effect.

Chang XM, Xiao F, Pan Q, Wang XX, Guo LX
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2021 Sep 1;25(5):425-437

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LncRNA OIP5-AS1 inhibits ferroptosis in prostate cancer with long-term cadmium exposure through miR-128-3p/SLC7A11 signaling.

Zhang Y, Guo S, Wang S, Li X, Hou D, Li H, Wang L, Xu Y, Ma B, Wang H, Jiang X
Ecotoxicology and environmental safety 2021 Sep 1;220:112376

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Yeast Shells Encapsulating Adjuvant AS04 as an Antigen Delivery System for a Novel Vaccine against Toxoplasma Gondii.

Zhu L, Lei Z, Xia X, Zhang Y, Chen Y, Wang B, Li J, Li G, Yang G, Cao G, Yin Z
ACS applied materials & interfaces 2021 Sep 1;13(34):40415-40428

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Radiation-Induced Autophagy in Human Pancreatic Cancer Cells is Critically Dependent on G2 Checkpoint Activation: A Mechanism of Radioresistance in Pancreatic Cancer.

Suzuki M, Anko M, Ohara M, Matsumoto KI, Hasegawa S
International journal of radiation oncology, biology, physics 2021 Sep 1;111(1):260-271

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Exosomes derived from induced pluripotent stem cells suppresses M2-type macrophages during pulmonary fibrosis via miR-302a-3p/TET1 axis.

Zhou Y, Gao Y, Zhang W, Chen Y, Jin M, Yang Z
International immunopharmacology 2021 Oct;99:108075

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JNK inhibition alleviates delayed neurocognitive recovery after surgery by limiting microglia pyroptosis.

He J, Liu T, Li Y, Mi X, Han D, Yang N, Chen L, Li Y, Hong J, Kuang C, Yuan Y, Cao Y, Han Y, Shi C, Li Z, Guo X
International immunopharmacology 2021 Oct;99:107962

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Thymus quinquecostatus Celak. ameliorates cerebral ischemia-reperfusion injury via dual antioxidant actions: Activating Keap1/Nrf2/HO-1 signaling pathway and directly scavenging ROS.

Fan S, Liu X, Wang Y, Ren X, Liu Y, Dong Y, Fan Q, Wei J, Ma J, Yu A, Song R, Sui H, Shen M, Fang F, Xia Q, She G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Oct;91:153673

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Lactobacillus casei relieves liver injury by regulating immunity and suppression of the enterogenic endotoxin-induced inflammatory response in rats cotreated with alcohol and iron.

Li X, Han J, Liu Y, Liang H
Food science & nutrition 2021 Oct;9(10):5391-5401

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Characteristics and clinical significance of polyploid giant cancer cells in laryngeal carcinoma.

Liu HT, Xia T, You YW, Zhang QC, Ni HS, Liu YF, Liu YR, Xu YQ, You B, Zhang ZX
Laryngoscope investigative otolaryngology 2021 Oct;6(5):1228-1234

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SETD3 Downregulation Mediates PTEN Upregulation-Induced Ischemic Neuronal Death Through Suppression of Actin Polymerization and Mitochondrial Function.

Xu X, Cui Y, Li C, Wang Y, Cheng J, Chen S, Sun J, Ren J, Yao X, Gao J, Huang X, Wan Q, Wang Q
Molecular neurobiology 2021 Oct;58(10):4906-4920

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Systematic screening identifies a TEAD4-S100A13 axis modulating cisplatin sensitivity of oral squamous cell carcinoma cells.

Li R, Li W, He F, Zhang M, Luo H, Tang H
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2021 Oct;50(9):882-890

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Alpha-ketoglutarate ameliorates pressure overload-induced chronic cardiac dysfunction in mice.

An D, Zeng Q, Zhang P, Ma Z, Zhang H, Liu Z, Li J, Ren H, Xu D
Redox biology 2021 Oct;46:102088

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CTHRC1 Knockdown Promotes Inflammatory Responses Partially by p38 MAPK Activation in Human Periodontal Ligament Cells.

Guo Y, Jiang C, Yao S, Ma L, Zhang H, Wang X, Xu S, Cao Z
Inflammation 2021 Oct;44(5):1831-1842

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Interleukin-38 Suppresses Cell Migration and Proliferation and Promotes Apoptosis of Colorectal Cancer Cell Through Negatively Regulating Extracellular Signal-Regulated Kinases Signaling.

Huang L, Zhang H, Zhao D, Hu H, Lu Z
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2021 Oct;41(10):375-384

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High-mobility group AT-Hook 1 mediates the role of nuclear factor I/X in osteogenic differentiation through activating canonical Wnt signaling.

Wu X, Wang X, Shan L, Zhou J, Zhang X, Zhu E, Yuan H, Wang B
Stem cells (Dayton, Ohio) 2021 Oct;39(10):1349-1361

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Autographa Californica Multiple Nucleopolyhedrovirus orf13 Is Required for Efficient Nuclear Egress of Nucleocapsids.

Chen X, Yang X, Lei C, Qin F, Sun X, Hu J
Virologica Sinica 2021 Oct;36(5):968-980

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An enzyme-responsive Gp1a-hydrogel for skin wound healing.

Zhao C, Dong Y, Liu J, Cai H, Li Z, Sun X, Yin W, Ma J, Liu H, Li S
Journal of biomaterials applications 2021 Oct;36(4):714-721

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Imbalanced inflammatory response in subchronic arsenic-induced liver injury and the protective effects of Ginkgo biloba extract in rats: Potential role of cytokines mediated cell-cell interactions.

Dong L, Liu Y, Wang D, Zhu K, Zou Z, Zhang A
Environmental toxicology 2021 Oct;36(10):2073-2092

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5-IP(7) is a GPCR messenger mediating neural control of synaptotagmin-dependent insulin exocytosis and glucose homeostasis.

Zhang X, Li N, Zhang J, Zhang Y, Yang X, Luo Y, Zhang B, Xu Z, Zhu Z, Yang X, Yan Y, Lin B, Wang S, Chen D, Ye C, Ding Y, Lou M, Wu Q, Hou Z, Zhang K, Liang Z, Wei A, Wang B, Wang C, Jiang N, Zhang W, Xiao G, Ma C, Ren Y, Qi X, Han W, Wang C, Rao F
Nature metabolism 2021 Oct;3(10):1400-1414

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Dynamin-related protein 1 regulates substrate oxidation in skeletal muscle by stabilizing cellular and mitochondrial calcium dynamics.

King WT, Axelrod CL, Zunica ERM, Noland RC, Davuluri G, Fujioka H, Tandler B, Pergola K, Hermann GE, Rogers RC, López-Domènech S, Dantas WS, Stadler K, Hoppel CL, Kirwan JP
The Journal of biological chemistry 2021 Oct;297(4):101196

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Arsenic Trioxide Combining Leflunomide Activates Nrf2-ARE-HO-1 Signaling Pathway and Protects Heart Xenografts.

Wang TD, Xu SL, Yu ZY, Ni SB, Zhang C, Jiao ZX
Chinese journal of integrative medicine 2021 Oct;27(10):760-766

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MicroRNA ssc-miR-124a exhibits antiviral activity against porcine reproductive and respiratory syndrome virus via suppression of host genes CD163.

Li N, Huang K, Chen Y, Huang Z, Zhang Y, Leng C, Liu Y, Shi J, Xiao S, Yao L
Veterinary microbiology 2021 Oct;261:109216

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TRIM21 negatively regulates Corynebacterium pseudotuberculosis-induced inflammation and is critical for the survival of C. pseudotuberculosis infected C57BL6 mice.

Tan J, Yi W, Wang Z, Ye C, Tian S, Li X, Zou A, Zhao X, Yuan Y, Wang X, Hu S, Zhou Z
Veterinary microbiology 2021 Oct;261:109209

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Reactive oxygen species induced by uric acid promote NRK‑52E cell apoptosis through the NEK7‑NLRP3 signaling pathway.

Li D, Wang L, Ou J, Wang C, Zhou J, Lu L, Wu Y, Gao J
Molecular medicine reports 2021 Oct;24(4)

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Hsa_circ_0004058 inhibits apoptosis of SRA01/04 cells by promoting autophagy via miR-186/ATG7 axis.

Wang Y, Wu Z, Huang Y, Zhang Y
Experimental eye research 2021 Oct;211:108721

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Advanced Maternal Age-associated SIRT1 Deficiency Compromises Trophoblast Epithelial-Mesenchymal Transition through an Increase in Vimentin Acetylation.

Xiong L, Ye X, Chen Z, Fu H, Li S, Xu P, Yu J, Wen L, Gao R, Fu Y, Qi H, Kilby MD, Saffery R, Baker PN, Tong C
Aging cell 2021 Oct;20(10):e13491

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Activation of angiotensin-converting enzyme 2/angiotensin (1-7)/mas receptor axis triggers autophagy and suppresses microglia proinflammatory polarization via forkhead box class O1 signaling.

Dang R, Yang M, Cui C, Wang C, Zhang W, Geng C, Han W, Jiang P
Aging cell 2021 Oct;20(10):e13480

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Peptides derived from viral glycoprotein Gc Inhibit infection of severe fever with thrombocytopenia syndrome virus.

Gao C, Yu Y, Wen C, Li Z, Sun M, Gao S, Lin S, Wang S, Zou P, Xing Z
Antiviral research 2021 Oct;194:105164

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RSL3 enhances the antitumor effect of cisplatin on prostate cancer cells via causing glycolysis dysfunction.

Li M, Chen X, Wang X, Wei X, Wang D, Liu X, Xu L, Batu W, Li Y, Guo B, Zhang L
Biochemical pharmacology 2021 Oct;192:114741

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PIKE-A promotes glioblastoma growth by driving PPP flux through increasing G6PD expression mediated by phosphorylation of STAT3.

Sun M, Sheng H, Wu T, Song J, Sun H, Wang Y, Wang J, Li Z, Zhao H, Tan J, Li Y, Chen G, Huang Q, Zhang Y, Lan B, Liu S, Shan C, Zhang S
Biochemical pharmacology 2021 Oct;192:114736

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Dihydroartemisinin regulates lipid droplet metabolism in hepatic stellate cells by inhibiting lncRNA-H19-induced AMPK signal.

Xia S, Wang Z, Chen L, Zhou Y, Li Y, Wang S, Chen A, Xu X, Shao J, Zhang Z, Tan S, Zhang F, Zheng S
Biochemical pharmacology 2021 Oct;192:114730

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LncRNA-Malat1 down-regulates miR-211-5p expression to promote neuronal damage from cerebral ischemia reperfusion injury.

Tan X, Guo W, Peng Z, Gu C, Xiang P, Tu Y, Fei H, Liu X, Lu Y, Li M, Wang H, Luo Y, Yang J
Biochemical pharmacology 2021 Oct;192:114694

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REM Sleep Deprivation Impairs Learning and Memory by Decreasing Brain O-GlcNAc Cycling in Mouse.

Kim SM, Zhang S, Park J, Sung HJ, Tran TT, Chung C, Han IO
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2021 Oct;18(4):2504-2517

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Ginsenoside Rg1 prevents bone marrow mesenchymal stem cell senescence via NRF2 and PI3K/Akt signaling.

Wang Z, Wang L, Jiang R, Li C, Chen X, Xiao H, Hou J, Hu L, Huang C, Wang Y
Free radical biology & medicine 2021 Oct;174:182-194

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A purified human platelet pellet lysate rich in neurotrophic factors and antioxidants repairs and protects corneal endothelial cells from oxidative stress.

Widyaningrum R, Burnouf T, Nebie O, Delila L, Wang TJ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:112046

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Panax notoginseng saponins reduces the cisplatin-induced acute renal injury by increasing HIF-1α/BNIP3 to inhibit mitochondrial apoptosis pathway.

Li Q, Zhang Y, Yang Y, Huang S, Zou X, Wei C, Liang T, Zhong X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:111965

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Deletion of ribosomal paralogs Rpl39 and Rpl39l compromises cell proliferation via protein synthesis and mitochondrial activity.

Zou Q, Qi H
The international journal of biochemistry & cell biology 2021 Oct;139:106070

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Design, synthesis and antitumor evaluation of novel chiral diaryl substituted azetidin-2-one derivatives as tubulin polymerization inhibitors.

Liang Y, Zhang M, Zhou P, Liu M, Li J, Wang Y
Bioorganic chemistry 2021 Oct;115:105239

---

Transcription factor POU4F2 promotes colorectal cancer cell migration and invasion through hedgehog-mediated epithelial-mesenchymal transition.

Guo K, Wang P, Zhang L, Zhou Y, Dai X, Yan Y, Chen Y, Wasan HS, Yu J, Ruan S, Sun L
Cancer science 2021 Oct;112(10):4176-4186

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ERK1/2 mitogen-activated protein kinase mediates downregulation of intestinal tight junction proteins in heat stress-induced IBD model in pig.

Yong Y, Li J, Gong D, Yu T, Wu L, Hu C, Liu X, Yu Z, Ma X, Gooneratne R, Abd El-Aty AM, Chen J, Ju X
Journal of thermal biology 2021 Oct;101:103103

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Aberrant expression of SNHG12 contributes to N, N-dimethylformamide-induced hepatic apoptosis both in short-term and long-term DMF exposure.

Liu Y, Wen C, Zhang Y, Liu Z, He Q, Cui M, Peng H, Wang Y, Zhang X, Li X, Wang Q
Toxicology research 2021 Oct;10(5):1022-1033

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Protocols for Characterization of Cdk5 Kinase Activity.

Terse A, Amin N, Hall B, Bhaskar M, B K B, Utreras E, Pareek TK, Pant H, Kulkarni AB
Current protocols 2021 Oct;1(10):e276

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CENPA promotes clear cell renal cell carcinoma progression and metastasis via Wnt/β-catenin signaling pathway.

Wang Q, Xu J, Xiong Z, Xu T, Liu J, Liu Y, Chen J, Shi J, Shou Y, Yue C, Liu D, Liang H, Yang H, Yang X, Zhang X
Journal of translational medicine 2021 Oct 9;19(1):417

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sTNFRII-Fc modification protects human UC-MSCs against apoptosis/autophagy induced by TNF-α and enhances their efficacy in alleviating inflammatory arthritis.

Zhao Y, Yang X, Li S, Zhang B, Li S, Wang X, Wang Y, Jia C, Chang Y, Wei W
Stem cell research & therapy 2021 Oct 9;12(1):535

---

Glycogen synthase kinase 3 drives thymocyte egress by suppressing β-catenin activation of Akt.

Liu C, Ma L, Wang Y, Zhao J, Chen P, Chen X, Wang Y, Hu Y, Liu Y, Jia X, Yang Z, Yin X, Wu J, Wu S, Zheng H, Ma X, Sun X, He Y, Lin L, Fu Y, Liao K, Zhou X, Jiang S, Fu G, Tang J, Han W, Chen XL, Fan W, Hong Y, Han J, Huang X, Li BA, Xiao N, Xiao C, Fu G, Liu WH
Science advances 2021 Oct 8;7(41):eabg6262

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TDAG51 induces renal interstitial fibrosis through modulation of TGF-β receptor 1 in chronic kidney disease.

Carlisle RE, Mohammed-Ali Z, Lu C, Yousof T, Tat V, Nademi S, MacDonald ME, Austin RC, Dickhout JG
Cell death & disease 2021 Oct 8;12(10):921

---

Sulforaphane downregulated fatty acid synthase and inhibited microtubule-mediated mitophagy leading to apoptosis.

Yan Y, Zhou Y, Li J, Zheng Z, Hu Y, Li L, Wu W
Cell death & disease 2021 Oct 7;12(10):917

---

Tetrahedral Framework Nucleic Acid Delivered RNA Therapeutics Significantly Attenuate Pancreatic Cancer Progression via Inhibition of CTR1-Dependent Copper Absorption.

Song G, Dong H, Ma D, Wang H, Ren X, Qu Y, Wu H, Zhu J, Song W, Meng Y, Wang L, Liu T, Shen X, Zhao Y, Zhu C
ACS applied materials & interfaces 2021 Oct 6;13(39):46334-46342

---

Leojaponin inhibits NLRP3 inflammasome activation through restoration of autophagy via upregulating RAPTOR phosphorylation.

Zhang XJ, Shang K, Pu YK, Wang Q, Wang TT, Zou Y, Wang YM, Xu YJ, Li XL, Zhang RH, Xiao WL
Journal of ethnopharmacology 2021 Oct 5;278:114322

---

p53 transcriptionally regulates SQLE to repress cholesterol synthesis and tumor growth.

Sun H, Li L, Li W, Yang F, Zhang Z, Liu Z, Du W
EMBO reports 2021 Oct 5;22(10):e52537

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PFP@PLGA/Cu(12)Sb(4)S(13)-mediated PTT ablates hepatocellular carcinoma by inhibiting the RAS/MAPK/MT-CO1 signaling pathway.

Dong T, Jiang J, Zhang H, Liu H, Zou X, Niu J, Mao Y, Zhu M, Chen X, Li Z, Chen Y, Shi C, Yang X
Nano convergence 2021 Oct 4;8(1):29

---

Activation of G protein coupled estrogen receptor prevents chemotherapy-induced intestinal mucositis by inhibiting the DNA damage in crypt cell in an extracellular signal-regulated kinase 1- and 2- dependent manner.

Chen G, Zeng H, Li X, Liu J, Li Z, Xu R, Ma Y, Liu C, Xue B
Cell death & disease 2021 Oct 30;12(11):1034

---

ATP-binding cassette protein ABCF1 couples transcription and genome surveillance in embryonic stem cells through low-complexity domain.

Choi EB, Vodnala M, Zerbato M, Wang J, Ho JJ, Inouye C, Ding L, Fong YW
Science advances 2021 Oct 29;7(44):eabk2775

---

Fructus Ligustri Lucidi aqueous extract promotes calcium balance and short-chain fatty acids production in ovariectomized rats.

Chen B, Wei J, Zhu R, Zhang H, Xia B, Liu Y, Dai X, Ye Z, Tian Y, Li R, Zhao D, Mo F, Orekhov AN, Gao S, Brὃmme D, Wang L, Zhang D
Journal of ethnopharmacology 2021 Oct 28;279:114348

---

Dysfunctional lactate metabolism in human alveolar type II cells from idiopathic pulmonary fibrosis lung explant tissue.

Newton DA, Lottes RG, Ryan RM, Spyropoulos DD, Baatz JE
Respiratory research 2021 Oct 28;22(1):278

---

Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation.

Ulferts R, Marcassa E, Timimi L, Lee LC, Daley A, Montaner B, Turner SD, Florey O, Baillie JK, Beale R
Cell reports 2021 Oct 26;37(4):109899

---

FABP4 is an independent risk factor for lymph node metastasis and poor prognosis in patients with cervical cancer.

Li G, Wu Q, Gong L, Xu X, Cai J, Xu L, Zeng Y, He X, Wang Z
Cancer cell international 2021 Oct 26;21(1):568

---

The overexpression of Tipe2 in CRC cells suppresses survival while endogenous Tipe2 accelerates AOM/DSS induced-tumor initiation.

Li Y, Zhang N, Ma C, Xu W, Jin G, Zheng Y, Zhang L, Liu B, Gao C, Liu S
Cell death & disease 2021 Oct 26;12(11):1001

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Circular RNA circPRKCI contributes to malignant progression of T-cell acute lymphoblastic leukemia by modulating miR-20a-5p/SOX4 axis.

Zheng Y, Niu B, Zhang W, Ru X, Gao Y, Li C, Wu X
Aging 2021 Oct 25;13(20):23757-23768

---

Glaesserella parasuis serotype 4 HPS4-YC disrupts the integrity of the swine tracheal epithelial barrier and facilitates bacterial translocation.

Wang Q, Chang X, Liu M, Lu Q, Zhu M, Lin H, Fan H
Veterinary research 2021 Oct 21;52(1):135

---

Layered Double Hydroxide Nanoparticles with Osteogenic Effects as miRNA Carriers to Synergistically Promote Osteogenesis of MSCs.

Yang L, He X, Jing G, Wang H, Niu J, Qian Y, Wang S
ACS applied materials & interfaces 2021 Oct 20;13(41):48386-48402

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Metformin sensitises hepatocarcinoma cells to methotrexate by targeting dihydrofolate reductase.

Wang Y, Lu H, Sun L, Chen X, Wei H, Suo C, Feng J, Yuan M, Shen S, Jia W, Wang Y, Zhang H, Li Z, Zhong X, Gao P
Cell death & disease 2021 Oct 2;12(10):902

---

ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis.

Karki R, Sundaram B, Sharma BR, Lee S, Malireddi RKS, Nguyen LN, Christgen S, Zheng M, Wang Y, Samir P, Neale G, Vogel P, Kanneganti TD
Cell reports 2021 Oct 19;37(3):109858

---

Synapse development is regulated by microglial THIK-1 K(+) channels.

Izquierdo P, Shiina H, Hirunpattarasilp C, Gillis G, Attwell D
Proceedings of the National Academy of Sciences of the United States of America 2021 Oct 19;118(42)

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Targeting CDC7 potentiates ATR-CHK1 signaling inhibition through induction of DNA replication stress in liver cancer.

Guo Y, Wang J, Benedict B, Yang C, van Gemert F, Ma X, Gao D, Wang H, Zhang S, Lieftink C, Beijersbergen RL, Te Riele H, Qiao X, Gao Q, Sun C, Qin W, Bernards R, Wang C
Genome medicine 2021 Oct 18;13(1):166

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Aronia melanocarpa polysaccharide ameliorates inflammation and aging in mice by modulating the AMPK/SIRT1/NF-κB signaling pathway and gut microbiota.

Zhao Y, Liu X, Zheng Y, Liu W, Ding C
Scientific reports 2021 Oct 18;11(1):20558

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Unexpected Implication of SRP and AGO2 in Parkinson's Disease: Involvement in Alpha-Synuclein Biogenesis.

Hernandez SM, Tikhonova EB, Baca KR, Zhao F, Zhu X, Karamyshev AL
Cells 2021 Oct 18;10(10)

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Thromboxane A(2) is involved in the development of hypertension in chronic kidney disease rats.

Hu J, Yang Z, Chen X, Kuang S, Lian Z, Ke G, Liao R, Ma J, Li S, Zhang L, Li Z, Feng Z, Liang H, Lin T, Dong W, Li R, Li Z, Chen Y, Liang X, Shi W, Deng C, Liu S
European journal of pharmacology 2021 Oct 15;909:174435

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A systematic approach to decode the mechanism of Cornus in the treatment of hepatocellular carcinoma (HCC).

Shen HY, Li XQ, Fan WQ, Wang YW, Huang F, Wu JQ, Zhang W, Feng XS, Chao X
European journal of pharmacology 2021 Oct 15;909:174405

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Antidepressant mechanism of catalpol: Involvement of the PI3K/Akt/Nrf2/HO-1 signaling pathway in rat hippocampus.

Wang J, Chen R, Liu C, Wu X, Zhang Y
European journal of pharmacology 2021 Oct 15;909:174396

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Pharmacological activation of SIRT1 by metformin prevented trauma-induced heterotopic ossification through inhibiting macrophage mediated inflammation.

Sun Z, Li J, Luo G, Liu W, He Y, Wang F, Qian Y, Fan C
European journal of pharmacology 2021 Oct 15;909:174386

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TRIM46 contributes to high glucose-induced ferroptosis and cell growth inhibition in human retinal capillary endothelial cells by facilitating GPX4 ubiquitination.

Zhang J, Qiu Q, Wang H, Chen C, Luo D
Experimental cell research 2021 Oct 15;407(2):112800

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The expression of IFN-β is suppressed by the viral 3D polymerase via its impact on PGAM5 expression during enterovirus D68 infection.

Yang Z, Zheng H, Li H, Chen Y, Hou D, Fan Q, Song J, Guo L, Liu L
Virus research 2021 Oct 15;304:198549

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NLRP3 inflammasome blocked the glycolytic pathway via targeting to PKLR in arsenic-induced hepatic insulin resistance.

Zhang J, Qiu T, Jiang L, Wang N, Zhu Y, Yan R, Wang S, Bai J, Shi X, Yang G, Liu X, Yao X, Sun X
Ecotoxicology and environmental safety 2021 Oct 15;223:112590

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5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma.

Wang S, Yang H, Su M, Lian F, Cong Z, Wei R, Zhou Y, Li X, Zheng X, Li C, Fu X, Han X, Shi Q, Li C, Zhang N, Geng M, Liu H, Li J, Huang X, Wang J
European journal of medicinal chemistry 2021 Oct 15;222:113592

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HBeAg mediates inflammatory functions of macrophages by TLR2 contributing to hepatic fibrosis.

Xie X, Lv H, Liu C, Su X, Yu Z, Song S, Bian H, Tian M, Qin C, Qi J, Zhu Q
BMC medicine 2021 Oct 15;19(1):247

---

The Timing and Effects of Low-Dose Ethanol Treatment on Acetaminophen-Induced Liver Injury.

Liu FC, Yu HP, Liao CC, Chou AH, Lee HC
Life (Basel, Switzerland) 2021 Oct 15;11(10)

---

Revisiting astrocyte to neuron conversion with lineage tracing in vivo.

Wang LL, Serrano C, Zhong X, Ma S, Zou Y, Zhang CL
Cell 2021 Oct 14;184(21):5465-5481.e16

---

The interaction of S100A16 and GRP78 actives endoplasmic reticulum stress-mediated through the IRE1α/XBP1 pathway in renal tubulointerstitial fibrosis.

Jin R, Zhao A, Han S, Zhang D, Sun H, Li M, Su D, Liang X
Cell death & disease 2021 Oct 13;12(10):942

---

Shift in MSL1 alternative polyadenylation in response to DNA damage protects cancer cells from chemotherapeutic agent-induced apoptosis.

Kunisky AK, Anyaeche VI, Herron RS, Park CY, Hwang HW
Cell reports 2021 Oct 12;37(2):109815

---

Vezatin regulates seizures by controlling AMPAR-mediated synaptic activity.

Wang Y, Yuan J, Yu X, Liu X, Tan C, Chen Y, Xu T
Cell death & disease 2021 Oct 12;12(10):936

---

Sitagliptin activates the p62-Keap1-Nrf2 signalling pathway to alleviate oxidative stress and excessive autophagy in severe acute pancreatitis-related acute lung injury.

Kong L, Deng J, Zhou X, Cai B, Zhang B, Chen X, Chen Z, Wang W
Cell death & disease 2021 Oct 11;12(10):928

---

Triiodothyronine ameliorates silica-induced pulmonary inflammation and fibrosis in mice.

Yang M, Wang D, Gan S, Wang B, Yu L, Xie Y, Fan L, Ma J, Chen W
The Science of the total environment 2021 Oct 10;790:148041

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Selenium Restores Synaptic Deficits by Modulating NMDA Receptors and Selenoprotein K in an Alzheimer's Disease Model.

Zhang ZH, Chen C, Jia SZ, Cao XC, Liu M, Tian J, Hoffmann PR, Xu HX, Ni JZ, Song GL
Antioxidants & redox signaling 2021 Oct 10;35(11):863-884

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Effects of Bacillus subtilis on jejunal integrity, redox status, and microbial composition of intrauterine growth restriction suckling piglets.

Yun Y, Ji S, Yu G, Jia P, Niu Y, Zhang H, Zhang X, Wang T, Zhang L
Journal of animal science 2021 Oct 1;99(10)

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Catalpol Weakens Depressive-like Behavior in Mice with Streptozotocin-induced Hyperglycemia via PI3K/AKT/Nrf2/HO-1 Signaling Pathway.

Wu X, Wang J, Song L, Guan Y, Cao C, Cui Y, Zhang Y, Liu C
Neuroscience 2021 Oct 1;473:102-118

---

GRIM-19 inhibits proliferation and induces apoptosis in a p53-dependent manner in colorectal cancer cells through the SIRT7/PCAF/MDM2 axis.

Wang D, Wei X, Chen X, Wang Q, Zhang J, Kalvakolanu DV, Guo B, Zhang L
Experimental cell research 2021 Oct 1;407(1):112799

---

EPS8 supports pancreatic cancer growth by inhibiting BMI1 mediated proteasomal degradation of ALDH7A1.

Tan M, Meng J, Sun X, Fu X, Wang R
Experimental cell research 2021 Oct 1;407(1):112782

---

Harpagide alleviate neuronal apoptosis and blood-brain barrier leakage by inhibiting TLR4/MyD88/NF-κB signaling pathway in Angiotensin II-induced microglial activation in vitro.

Lu Y, Hao R, Hu Y, Wei Y, Xie Y, Shen Y, Rui Q, Yu G
Chemico-biological interactions 2021 Oct 1;348:109653

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Antagonizing effects of curcumin against mercury-induced autophagic death and trace elements disorder by regulating PI3K/AKT and Nrf2 pathway in the spleen.

Zhao G, Qi L, Wang Y, Li X, Li Q, Tang X, Wang X, Wu C
Ecotoxicology and environmental safety 2021 Oct 1;222:112529

---

Cadmium promotes apoptosis and inflammation via the circ08409/miR-133a/TGFB2 axis in bovine mammary epithelial cells and mouse mammary gland.

Chen Z, Liang Y, Lu Q, Nazar M, Mao Y, Aboragah A, Yang Z, Loor JJ
Ecotoxicology and environmental safety 2021 Oct 1;222:112477

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Cellular OCIAD2 protein is a proviral factor for hepatitis C virus replication.

Yang Z, Ouyang T, Aoyagi H, Wang T, Xing X, Zhang Y, Wang Y, Li Y, Aizaki H, Li S, Kong L
International journal of biological macromolecules 2021 Oct 1;188:147-159

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Switch receptor T3/28 improves long-term persistence and antitumor efficacy of CAR-T cells.

Zhao S, Wang C, Lu P, Lou Y, Liu H, Wang T, Yang S, Bao Z, Han L, Liang X, Ma C, Gao L
Journal for immunotherapy of cancer 2021 Nov;9(12)

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Nitrate increases cisplatin chemosensitivity of oral squamous cell carcinoma via REDD1/AKT signaling pathway.

Feng Y, Cao X, Zhao B, Song C, Pang B, Hu L, Zhang C, Wang J, He J, Wang S
Science China. Life sciences 2021 Nov;64(11):1814-1828

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Hsa-miR-372-5p regulates the NIMA related kinase 7 and IL-1β release in NK/T-cell lymphoma.

Chen Q, Liu S, Zhang K, Yu B, Zhang W, Zhang H, Chen X
Leukemia & lymphoma 2021 Nov;62(11):2648-2656

---

D-mannose alleviates osteoarthritis progression by inhibiting chondrocyte ferroptosis in a HIF-2α-dependent manner.

Zhou X, Zheng Y, Sun W, Zhang Z, Liu J, Yang W, Yuan W, Yi Y, Wang J, Liu J
Cell proliferation 2021 Nov;54(11):e13134

---

Selenoprotein K deficiency-induced apoptosis: A role for calpain and the ERS pathway.

Jia SZ, Xu XW, Zhang ZH, Chen C, Chen YB, Huang SL, Liu Q, Hoffmann PR, Song GL
Redox biology 2021 Nov;47:102154

---

Curcumol inhibits the malignant progression of prostate cancer and regulates the PDK1/AKT/mTOR pathway by targeting miR‑9.

Sheng W, Xu W, Ding J, Li L, You X, Wu Y, He Q
Oncology reports 2021 Nov;46(5)

---

Protein kinase G signaling pathway is involved in sympathetically maintained pain by modulating ATP-sensitive potassium channels.

Li H, Shang M, Liu L, Lin X, Hu J, Han Q, Xing J
Regional anesthesia and pain medicine 2021 Nov;46(11):1006-1011

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Interleukin-17 upregulation participates in the pathogenesis of heart failure in mice via NF-κB-dependent suppression of SERCA2a and Cav1.2 expression.

Xue GL, Li DS, Wang ZY, Liu Y, Yang JM, Li CZ, Li XD, Ma JD, Zhang MM, Lu YJ, Li Y, Yang BF, Pan ZW
Acta pharmacologica Sinica 2021 Nov;42(11):1780-1789

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Oxidative stress-mediated apoptosis is involved in bisphenol S-induced reproductive toxicity in male C57BL/6 mice.

Dai W, He QZ, Zhu BQ, Zeng HC
Journal of applied toxicology : JAT 2021 Nov;41(11):1839-1851

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Propylparaben concentrations in the urine of women and adverse effects on ovarian function in mice in vivo and ovarian cells in vitro.

Jiao L, Li S, Zhai J, Wang D, Li H, Chu W, Geng X, Du Y
Journal of applied toxicology : JAT 2021 Nov;41(11):1719-1731

---

Proteasome inhibition induces macrophage apoptosis via mitochondrial dysfunction.

Wang J, Wang Y, He S, Wang Z, Deng Q, Liang H
Journal of biochemical and molecular toxicology 2021 Nov;35(11):e22894

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Rutaecarpine alleviates acute pancreatitis in mice and AR42J cells by suppressing the MAPK and NF-κB signaling pathways via calcitonin gene-related peptide.

Huang H, Wang M, Guo Z, Wu D, Wang H, Jia Y, Liu H, Ding J, Peng J
Phytotherapy research : PTR 2021 Nov;35(11):6472-6485

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Icariin attenuates renal fibrosis in chronic kidney disease by inhibiting interleukin-1β/transforming growth factor-β-mediated activation of renal fibroblasts.

Wang M, Wang L, Zhou Y, Feng X, Ye C, Wang C
Phytotherapy research : PTR 2021 Nov;35(11):6204-6215

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NudCL2 is an autophagy receptor that mediates selective autophagic degradation of CP110 at mother centrioles to promote ciliogenesis.

Liu M, Zhang W, Li M, Feng J, Kuang W, Chen X, Yang F, Sun Q, Xu Z, Hua J, Yang C, Liu W, Shu Q, Yang Y, Zhou T, Xie S
Cell research 2021 Nov;31(11):1199-1211

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A peptide CORO1C-47aa encoded by the circular noncoding RNA circ-0000437 functions as a negative regulator in endometrium tumor angiogenesis.

Li F, Cai Y, Deng S, Yang L, Liu N, Chang X, Jing L, Zhou Y, Li H
The Journal of biological chemistry 2021 Nov;297(5):101182

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Environmental Pollutant Benzo[a]pyrene Upregulated Long Non-coding RNA HZ07 Inhibits Trophoblast Cell Migration by Inactivating PI3K/AKT/MMP2 Signaling Pathway in Recurrent Pregnancy Loss.

Ye Y, Jiang S, Du T, Ding M, Hou M, Mi C, Liang T, Zhong H, Xie J, Xu W, Zhang H, Zhao X
Reproductive sciences (Thousand Oaks, Calif.) 2021 Nov;28(11):3085-3093

---

miR‑486‑5p suppresses gastric cancer cell growth and migration through downregulation of fibroblast growth factor 9.

Wei W, Liu C, Yao R, Tan Q, Wang Q, Tian H
Molecular medicine reports 2021 Nov;24(5)

---

Low-dose exposure to black carbon significantly increase lung injury of cadmium by promoting cellular apoptosis.

Wang L, Bao S, Liu X, Wang F, Zhang J, Dang P, Wang F, Li B, Lin Y
Ecotoxicology and environmental safety 2021 Nov;224:112703

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Gas6/Axl signaling pathway promotes proliferation, migration and invasion and inhibits apoptosis in A549 cells.

Wang D, Bi L, Ran J, Zhang L, Xiao N, Li X
Experimental and therapeutic medicine 2021 Nov;22(5):1321

---

Metformin attenuates H(2)O(2)-induced osteoblast apoptosis by regulating SIRT3 via the PI3K/AKT pathway.

Yang K, Pei L, Zhou S, Tao L, Zhu Y
Experimental and therapeutic medicine 2021 Nov;22(5):1316

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The anti-neoplastic activities of aloperine in HeLa cervical cancer cells are associated with inhibition of the IL-6-JAK1-STAT3 feedback loop.

Chen YD, Cai FY, Mao YZ, Yang YS, Xu K, Liu XF, Fan WW, Chen W, Jiang FQ, Zhang H
Chinese journal of natural medicines 2021 Nov;19(11):815-824

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Tau phosphorylation and OPA1 proteolysis are unrelated events: Implications for Alzheimer's Disease.

Alavi MV
Biochimica et biophysica acta. Molecular cell research 2021 Nov;1868(12):119116

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Chemical Constituents from the Rhizome of Ligusticum chuanxiong Hort. and Their Nrf2 Inducing Activity.

Zhang K, Fang KL, Wang T, Xu LT, Zhao Y, Wang XN, Xiang L, Shen T
Chemistry & biodiversity 2021 Nov;18(11):e2100302

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Chitotriosidase attenuates brain inflammation via HDAC3/NF-κB pathway in D-galactose and aluminum-induced rat model with cognitive impairments.

Yu X, Yu W, Wu L, Yang W, Lü Y
Neuroscience research 2021 Nov;172:73-79

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The differentiation state of the Schwann cell progenitor drives phenotypic variation between two contagious cancers.

Owen RS, Ramarathinam SH, Bailey A, Gastaldello A, Hussey K, Skipp PJ, Purcell AW, Siddle HV
PLoS pathogens 2021 Nov;17(11):e1010033

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Perfluorooctane sulfonate induces autophagy-dependent lysosomal membrane permeabilization by weakened interaction between tyrosinated alpha-tubulin and spinster 1.

Dong Z, Qiu T, Zhang J, Sha S, Han X, Kang J, Shi X, Sun X, Jiang L, Yang G, Yao X, Ma Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112540

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Gastrodin promotes hippocampal neurogenesis via PDE9-cGMP-PKG pathway in mice following cerebral ischemia.

Xiao H, Jiang Q, Qiu H, Wu K, Ma X, Yang J, Cheng O
Neurochemistry international 2021 Nov;150:105171

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Comparative proteomics reveals Cryptosporidium parvum manipulation of the host cell molecular expression and immune response.

Li T, Liu H, Jiang N, Wang Y, Wang Y, Zhang J, Shen Y, Cao J
PLoS neglected tropical diseases 2021 Nov;15(11):e0009949

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Trophoblast-derived interleukin 9 mediates immune cell conversion and contributes to maternal-fetal tolerance.

Sun Y, Wu S, Zhou Q, Li X
Journal of reproductive immunology 2021 Nov;148:103379

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Dopamine receptor 2 downregulation and brain-derived neurotrophic factor upregulation in the paraventricular nucleus are correlated with brown adipose tissue thermogenesis in rats with bilateral substantia nigra lesions.

Zhang Y, Zhou L, Lian H, Zhang Y, Tong S, Wang Z
Journal of chemical neuroanatomy 2021 Nov;117:102016

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miRNA-223-3p modulates ibrutinib resistance through regulation of the CHUK/Nf-κb signaling pathway in mantle cell lymphoma.

Yuan J, Zhang Q, Wu S, Yan S, Zhao R, Sun Y, Tian X, Zhou K
Experimental hematology 2021 Nov;103:52-59.e2

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Isoliquiritigenin alleviates LPS/ D-GalN-induced acute liver failure by activating the PGC-1α/ Nrf2 pathway to reduce oxidative stress and inflammatory response.

Wang L, Wang X, Kong L, Wang S, Huang K, Wu J, Wang C, Sun H, Liu K, Meng Q
International immunopharmacology 2021 Nov;100:108159

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Functional role of galectin-9 in directing human innate immune reactions to Gram-negative bacteria and T cell apoptosis.

Schlichtner S, Meyer NH, Yasinska IM, Aliu N, Berger SM, Gibbs BF, Fasler-Kan E, Sumbayev VV
International immunopharmacology 2021 Nov;100:108155

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The CCAAT-binding complex mediates azole susceptibility of Aspergillus fumigatus by suppressing SrbA expression and cleavage.

Zhang C, Gao L, Ren Y, Gu H, Zhang Y, Lu L
MicrobiologyOpen 2021 Nov;10(6):e1249

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Ultrathin 2D Titanium Carbide MXene (Ti(3) C(2) T(x) ) Nanoflakes Activate WNT/HIF-1α-Mediated Metabolism Reprogramming for Periodontal Regeneration.

Cui D, Kong N, Ding L, Guo Y, Yang W, Yan F
Advanced healthcare materials 2021 Nov;10(22):e2101215

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DNMT1-induced miR-378a-3p silencing promotes angiogenesis via the NF-κB signaling pathway by targeting TRAF1 in hepatocellular carcinoma.

Zhu B, Chen JJ, Feng Y, Yang JL, Huang H, Chung WY, Hu YL, Xue WJ
Journal of experimental & clinical cancer research : CR 2021 Nov 8;40(1):352

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High throughput sequencing of whole transcriptome and construct of ceRNA regulatory network in RD cells infected with enterovirus D68.

Si J, Tang X, Xu L, Fu H, Li H, He Y, Bao J, Tang J, Li A, Lu N, Yang C
Virology journal 2021 Nov 7;18(1):216

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Betaine alleviates right ventricular failure via regulation of Rho A/ROCK signaling pathway in rats with pulmonary arterial hypertension.

Lv Y, Ma P, Wang J, Xu Q, Fan J, Yan L, Ma P, Zhou R
European journal of pharmacology 2021 Nov 5;910:174311

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Discovery of a potent MLL1 and WDR5 protein-protein interaction inhibitor with in vivo antitumor activity.

Chen W, Chen X, Li D, Wang X, Long G, Jiang Z, You Q, Guo X
European journal of medicinal chemistry 2021 Nov 5;223:113677

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NOX4-derived ROS-induced overexpression of FOXM1 regulates aerobic glycolysis in glioblastoma.

Su X, Yang Y, Yang Q, Pang B, Sun S, Wang Y, Qiao Q, Guo C, Liu H, Pang Q
BMC cancer 2021 Nov 5;21(1):1181

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Photobiomodulation inhibits the activation of neurotoxic microglia and astrocytes by inhibiting Lcn2/JAK2-STAT3 crosstalk after spinal cord injury in male rats.

Wang X, Li X, Zuo X, Liang Z, Ding T, Li K, Ma Y, Li P, Zhu Z, Ju C, Zhang Z, Song Z, Quan H, Zhang J, Hu X, Wang Z
Journal of neuroinflammation 2021 Nov 5;18(1):256

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Ex vivo to in vivo extrapolation of syringic acid and ferulic acid as grape juice proxies for endothelium-dependent vasodilation: Redefining vasoprotective resveratrol of the French paradox.

Huang Y, Xu M, Li J, Chen K, Xia L, Wang W, Ren P, Huang X
Food chemistry 2021 Nov 30;363:130323

---

WFS1 functions in ER export of vesicular cargo proteins in pancreatic β-cells.

Wang L, Liu H, Zhang X, Song E, Wang Y, Xu T, Li Z
Nature communications 2021 Nov 30;12(1):6996

---

Hyaluronic acid hydrogel encapsulated BMP-14-modified ADSCs accelerate cartilage defect repair in rabbits.

Liu H, Rui Y, Liu J, Gao F, Jin Y
Journal of orthopaedic surgery and research 2021 Nov 3;16(1):657

---

Taxifolin retards the D-galactose-induced aging process through inhibiting Nrf2-mediated oxidative stress and regulating the gut microbiota in mice.

Liu XL, Zhao YC, Zhu HY, Wu M, Zheng YN, Yang M, Cheng ZQ, Ding CB, Liu WC
Food & function 2021 Nov 29;12(23):12142-12158

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Metformin Improves Stemness of Human Adipose-Derived Stem Cells by Downmodulation of Mechanistic Target of Rapamycin (mTOR) and Extracellular Signal-Regulated Kinase (ERK) Signaling.

Chinnapaka S, Yang KS, Flowers Q, Faisal M, Nerone WV, Rubin JP, Ejaz A
Biomedicines 2021 Nov 27;9(12)

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Structure-Based Discovery of Potent CARM1 Inhibitors for Solid Tumor and Cancer Immunology Therapy.

Zhang Z, Guo Z, Xu X, Cao D, Yang H, Li Y, Shi Q, Du Z, Guo X, Wang X, Chen D, Zhang Y, Chen L, Zhou K, Li J, Geng M, Huang X, Xiong B
Journal of medicinal chemistry 2021 Nov 25;64(22):16650-16674

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Proteolysis-Targeting Chimera (PROTAC) Modification of Dovitinib Enhances the Antiproliferative Effect against FLT3-ITD-Positive Acute Myeloid Leukemia Cells.

Cao S, Ma L, Liu Y, Wei M, Yao Y, Li C, Wang R, Liu N, Dong Z, Li X, Li M, Wang X, Yang C, Yang G
Journal of medicinal chemistry 2021 Nov 25;64(22):16497-16511

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Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion.

Zeng L, Zhou J, Wang X, Zhang Y, Wang M, Su P
Free radical biology & medicine 2021 Nov 20;176:176-188

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Effect of combination therapy with neural stem cell transplantation and teramethylpyrazine in rats following acute spinal cord injury.

Zhang H, Huang Z, Guo M, Meng L, Piao M, Zhang M, Yu H
Neuroreport 2021 Nov 2;32(16):1311-1319

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HIF-1-regulated expression of calreticulin promotes breast tumorigenesis and progression through Wnt/β-catenin pathway activation.

Liu X, Xie P, Hao N, Zhang M, Liu Y, Liu P, Semenza GL, He J, Zhang H
Proceedings of the National Academy of Sciences of the United States of America 2021 Nov 2;118(44)

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The Protective Role of Yin-Yang 1 in Cardiac Injury and Remodeling After Myocardial Infarction.

Huang Y, Li L, Chen H, Liao Q, Yang X, Yang D, Xia X, Wang H, Wang WE, Chen L, Zeng C
Journal of the American Heart Association 2021 Nov 2;10(21):e021895

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Identification of proximal SUMO-dependent interactors using SUMO-ID.

Barroso-Gomila O, Trulsson F, Muratore V, Canosa I, Merino-Cacho L, Cortazar AR, Pérez C, Azkargorta M, Iloro I, Carracedo A, Aransay AM, Elortza F, Mayor U, Vertegaal ACO, Barrio R, Sutherland JD
Nature communications 2021 Nov 18;12(1):6671

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Fluoride Stimulates Anxiety- and Depression-like Behaviors Associated with SIK2-CRTC1 Signaling Dysfunction.

Zhou G, Hu Y, Wang A, Guo M, Du Y, Gong Y, Ding L, Feng Z, Hou X, Xu K, Yu F, Li Z, Ba Y
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13618-13627

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Dendrobium officinale Polysaccharide Alleviates Intestinal Inflammation by Promoting Small Extracellular Vesicle Packaging of miR-433-3p.

Liu H, Liang J, Zhong Y, Xiao G, Efferth T, Georgiev MI, Vargas-De-La-Cruz C, Bajpai VK, Caprioli G, Liu J, Lin J, Wu H, Peng L, Li Y, Ma L, Xiao J, Wang Q
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13510-13523

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Role of Epigallocatechin Gallate in Glucose, Lipid, and Protein Metabolism and L-Theanine in the Metabolism-Regulatory Effects of Epigallocatechin Gallate.

Lin L, Zeng L, Liu A, Yuan D, Peng Y, Zhang S, Li Y, Chen J, Xiao W, Gong Z
Nutrients 2021 Nov 17;13(11)

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Exopolysaccharides from Bifidobacterium animalis Ameliorate Escherichia coli-Induced IPEC-J2 Cell Damage via Inhibiting Apoptosis and Restoring Autophagy.

Yuan L, Chu B, Chen S, Li Y, Liu N, Zhu Y, Zhou D
Microorganisms 2021 Nov 16;9(11)

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Astragalus polysaccharide prevents ferroptosis in a murine model of experimental colitis and human Caco-2 cells via inhibiting NRF2/HO-1 pathway.

Chen Y, Wang J, Li J, Zhu J, Wang R, Xi Q, Wu H, Shi T, Chen W
European journal of pharmacology 2021 Nov 15;911:174518

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HMMR is a downstream target of FOXM1 in enhancing proliferation and partial epithelial-to-mesenchymal transition of bladder cancer cells.

Yang D, Ma Y, Zhao P, Ma J, He C
Experimental cell research 2021 Nov 15;408(2):112860

---

3-Epipachysamine B suppresses proliferation and induces apoptosis of breast cancer cell via PI3K/AKT/mTOR signaling pathway.

Zhang L, Zheng Y, Zeng L, Zhang F, Che D, Cao Z, Huang C, Xian L, Zhang X, Zhang H, Guo Z
Life sciences 2021 Nov 15;285:119995

---

Si-Wu-Tang facilitates ovarian function through improving ovarian microenvironment and angiogenesis in a mouse model of premature ovarian failure.

Zhou F, Song Y, Liu X, Zhang C, Li F, Hu R, Huang Y, Ma W, Song K, Zhang M
Journal of ethnopharmacology 2021 Nov 15;280:114431

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Protective effect of the effective part of Andrographis paniculata (Burm.f.) Nees on PM(2.5)-induced lung injury in rats by modulating the NF-κB pathway.

Yao H, Zhao J, Zhu L, Xie Y, Zhao N, Yao R, Sun H, Han G
Journal of ethnopharmacology 2021 Nov 15;280:114420

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Yi-Qi-Jian-Pi formula modulates the PI3K/AKT signaling pathway to attenuate acute-on-chronic liver failure by suppressing hypoxic injury and apoptosis in vivo and in vitro.

Tang L, Wang F, Xiao L, Shen M, Xia S, Zhang Z, Zhang F, Zheng S, Tan S
Journal of ethnopharmacology 2021 Nov 15;280:114411

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Cutting Edge: Caspase-8 Is a Linchpin in Caspase-3 and Gasdermin D Activation to Control Cell Death, Cytokine Release, and Host Defense during Influenza A Virus Infection.

Wang Y, Karki R, Zheng M, Kancharana B, Lee S, Kesavardhana S, Hansen BS, Pruett-Miller SM, Kanneganti TD
Journal of immunology (Baltimore, Md. : 1950) 2021 Nov 15;207(10):2411-2416

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SARS-CoV-2 inhibits induction of the MHC class I pathway by targeting the STAT1-IRF1-NLRC5 axis.

Yoo JS, Sasaki M, Cho SX, Kasuga Y, Zhu B, Ouda R, Orba Y, de Figueiredo P, Sawa H, Kobayashi KS
Nature communications 2021 Nov 15;12(1):6602

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Heat stress induces oxidative stress and activates the KEAP1-NFE2L2-ARE pathway in bovine endometrial epithelial cells†.

Murata H, Kunii H, Kusama K, Sakurai T, Bai H, Kawahara M, Takahashi M
Biology of reproduction 2021 Nov 15;105(5):1114-1125

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Xbp1s-Ddit3 promotes MCT-induced pulmonary hypertension.

Jiang H, Ding D, He Y, Li X, Xu Y, Liu X
Clinical science (London, England : 1979) 2021 Nov 12;135(21):2467-2481

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The Mutational Landscape of PTK7 in Congenital Scoliosis and Adolescent Idiopathic Scoliosis.

Su Z, Yang Y, Wang S, Zhao S, Zhao H, Li X, Niu Y, Deciphering Disorders Involving Scoliosis And COmorbidities Disco Study Group, Qiu G, Wu Z, Wu N, Zhang TJ
Genes 2021 Nov 12;12(11)

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Phase separation drives RNA virus-induced activation of the NLRP6 inflammasome.

Shen C, Li R, Negro R, Cheng J, Vora SM, Fu TM, Wang A, He K, Andreeva L, Gao P, Tian Z, Flavell RA, Zhu S, Wu H
Cell 2021 Nov 11;184(23):5759-5774.e20

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Erythritol Improves Nonalcoholic Fatty Liver Disease by Activating Nrf2 Antioxidant Capacity.

Jin M, Wei Y, Yu H, Ma X, Yan S, Zhao L, Ding L, Cheng J, Feng H
Journal of agricultural and food chemistry 2021 Nov 10;69(44):13080-13092

---

AICAR enhances the cytotoxicity of PFKFB3 inhibitor in an AMPK signaling-independent manner in colorectal cancer cells.

Yan S, Yuan D, Li Q, Li S, Zhang F
Medical oncology (Northwood, London, England) 2021 Nov 10;39(1):10

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Isorhapontigenin (ISO) inhibits EMT through FOXO3A/METTL14/VIMENTIN pathway in bladder cancer cells.

Zhang N, Hua X, Tu H, Li J, Zhang Z, Max C
Cancer letters 2021 Nov 1;520:400-408

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SAA1 is transcriptionally activated by STAT3 and accelerates renal interstitial fibrosis by inducing endoplasmic reticulum stress.

Zhang F, Zhou X, Zou H, Liu L, Li X, Ruan Y, Xie Y, Shi M, Xiao Y, Wang Y, Zhou Y, Wu Y, Guo B
Experimental cell research 2021 Nov 1;408(1):112856

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Competing endogenous RNA network associated with oxygen-induced retinopathy: Expression of the network and identification of the MALAT1/miR-124-3p/EGR1 regulatory axis.

Xia F, Xu Y, Zhang X, Lyu J, Zhao P
Experimental cell research 2021 Nov 1;408(1):112783

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A naturally occurring FXR agonist, alisol B 23-acetate, protects against renal ischemia-reperfusion injury.

Luan ZL, Ming WH, Sun XW, Zhang C, Zhou Y, Zheng F, Yang YL, Guan YF, Zhang XY
American journal of physiology. Renal physiology 2021 Nov 1;321(5):F617-F628

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Vps13D functions in a Pink1-dependent and Parkin-independent mitophagy pathway.

Shen JL, Fortier TM, Wang R, Baehrecke EH
The Journal of cell biology 2021 Nov 1;220(11)

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LncRNA NEAT1 mediates intestinal inflammation by regulating TNFRSF1B.

Pan S, Liu R, Wu X, Ma K, Luo W, Nie K, Zhang C, Meng X, Tong T, Chen X, Wang X, Deng M
Annals of translational medicine 2021 May;9(9):773

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Deleterious impact of nerve growth factor precursor (proNGF) on bladder urothelial and smooth muscle cells.

Mossa AH, Abdaem J, Cammisotto P, Campeau L
Cellular signalling 2021 May;81:109936

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Efficient Killing of Multidrug-Resistant Internalized Bacteria by AIEgens In Vivo.

Li Y, Liu F, Zhang J, Liu X, Xiao P, Bai H, Chen S, Wang D, Sung SHP, Kwok RTK, Shen J, Zhu K, Tang BZ
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 May;8(9):2001750

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Amelioration of Murine Macrophage Activation Syndrome by Monomethyl Fumarate in Both a Heme Oxygenase 1-Dependent and Heme Oxygenase 1-Independent Manner.

Biswas C, Chu N, Burn TN, Kreiger PA, Behrens EM
Arthritis & rheumatology (Hoboken, N.J.) 2021 May;73(5):885-895

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Elevated type I interferon responses potentiate metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice.

Lei Y, Guerra Martinez C, Torres-Odio S, Bell SL, Birdwell CE, Bryant JD, Tong CW, Watson RO, West LC, West AP
Science advances 2021 May;7(22)

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Novel Japanese encephalitis virus NS1-based vaccine: Truncated NS1 fused with E. coli heat labile enterotoxin B subunit.

Wan J, Wang T, Xu J, Ouyang T, Wang Q, Zhang Y, Weng S, Li Y, Wang Y, Xin X, Wang X, Li S, Kong L
EBioMedicine 2021 May;67:103353

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Cu-induced mitochondrial dysfunction is mediated by abnormal mitochondrial fission through oxidative stress in primary chicken embryo hepatocytes.

Wu L, Kang Z, Qiao N, Wang C, Tang Z
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2021 May;65:126721

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Changes of lipid profiles in human umbilical vein endothelial cells exposed to zirconia nanoparticles with or without the presence of free fatty acids.

Cheng X, Guo H, Xian Y, Xie X
Journal of applied toxicology : JAT 2021 May;41(5):765-774

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Comparison of toxicity of Ti(3) C(2) and Nb(2) C Mxene quantum dots (QDs) to human umbilical vein endothelial cells.

Gu M, Dai Z, Yan X, Ma J, Niu Y, Lan W, Wang X, Xu Q
Journal of applied toxicology : JAT 2021 May;41(5):745-754

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Long non-coding RNA LEISA promotes progression of lung adenocarcinoma via enhancing interaction between STAT3 and IL-6 promoter.

Wu S, Liu B, Zhang Y, Hong R, Liu S, Xiang T, Tao T, Cai J, Wu J, Li M, Guan H
Oncogene 2021 May;40(19):3449-3459

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miR-509-3p Suppresses Migration, Invasion, and Epithelial- Mesenchymal Transition in Melanoma Cells by Targeting Collagen Triple Helix Repeat Containing 1.

Yuan K, Sun Y, Ji Y
Balkan medical journal 2021 May;38(3):177-182

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Cross-talk Between Histone and DNA Methylation Mediates Bone Loss in Hind Limb Unloading.

Li B, Zhao J, Ma J, Chen W, Zhou C, Wei W, Li S, Li G, Xin G, Zhang Y, Liu J, Wang Y, Ma X
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2021 May;36(5):956-967

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Long noncoding RNA DUXAP10 promotes the stemness of glioma cells by recruiting HuR to enhance Sox12 mRNA stability.

Wu B, Yang C, Fang Y, Ding W, Zhang Y
Environmental toxicology 2021 May;36(5):840-849

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Glucose-dependent insulinotropic polypeptide modifies adipose plasticity and promotes beige adipogenesis of human omental adipose-derived stem cells.

Chen X, He X, Guo Y, Liu L, Li H, Tan J, Feng W, Guan H, Cao X, Xiao H, Li Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21534

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Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer's disease.

Bao WD, Pang P, Zhou XT, Hu F, Xiong W, Chen K, Wang J, Wang F, Xie D, Hu YZ, Han ZT, Zhang HH, Wang WX, Nelson PT, Chen JG, Lu Y, Man HY, Liu D, Zhu LQ
Cell death and differentiation 2021 May;28(5):1548-1562

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Cholesterol 25-hydroxylase inhibits Senecavirus A replication by enzyme activity-dependent and independent mechanisms.

Zhu H, Yan J, Liu X, Li L, Liu W, Wang X, Jiang P, Bai J
Veterinary microbiology 2021 May;256:109038

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IL-1/IL-1R signaling induced by all-trans-retinal contributes to complement alternative pathway activation in retinal pigment epithelium.

Cheng X, He D, Liao C, Lin S, Tang L, Wang YL, Hu J, Li W, Liu Z, Wu Y, Liao Y
Journal of cellular physiology 2021 May;236(5):3660-3674

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Synergistic effects of olaparib combined with ERCC1 on the sensitivity of cisplatin in non-small cell lung cancer.

Xie K, Ni X, Lv S, Zhou G, He H
Oncology letters 2021 May;21(5):365

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Free Deoxycholic Acid Exacerbates Vascular Calcification in CKD through ER Stress-Mediated ATF4 Activation.

Miyazaki-Anzai S, Masuda M, Shiozaki Y, Keenan AL, Chonchol M, Kremoser C, Miyazaki M
Kidney360 2021 May;2(5):857-868

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Long non-coding RNA PCA3 inhibits lipid accumulation and atherosclerosis through the miR-140-5p/RFX7/ABCA1 axis.

Zhao ZW, Zhang M, Liao LX, Zou J, Wang G, Wan XJ, Zhou L, Li H, Qin YS, Yu XH, Tang CK
Biochimica et biophysica acta. Molecular and cell biology of lipids 2021 May;1866(5):158904

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Anti-osteoporotic effects of alisol C 23-acetate via osteoclastogenesis inhibition.

Jia X, Zhu H, Li G, Lan M, Li X, Huang M, Xu W, Wu S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 May;137:111321

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Reversine suppresses osteosarcoma cell growth through targeting BMP-Smad1/5/8-mediated angiogenesis.

Hu L, Li K, Lin L, Qian F, Li P, Zhu L, Cai H, You L, Song J, Kok SHL, Lee KKH, Yang X, Cheng X
Microvascular research 2021 May;135:104136

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Inhibition of NLRP3 inflammasome ameliorates podocyte damage by suppressing lipid accumulation in diabetic nephropathy.

Wu M, Yang Z, Zhang C, Shi Y, Han W, Song S, Mu L, Du C, Shi Y
Metabolism: clinical and experimental 2021 May;118:154748

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SREBP1/FASN/cholesterol axis facilitates radioresistance in colorectal cancer.

Jin Y, Chen Z, Dong J, Wang B, Fan S, Yang X, Cui M
FEBS open bio 2021 May;11(5):1343-1352

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Multi-omics approaches identify SF3B3 and SIRT3 as candidate autophagic regulators and druggable targets in invasive breast carcinoma.

Zhang S, Zhang J, An Y, Zeng X, Qin Z, Zhao Y, Xu H, Liu B
Acta pharmaceutica Sinica. B 2021 May;11(5):1227-1245

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De novo purine biosynthesis is a major driver of chemoresistance in glioblastoma.

Shireman JM, Atashi F, Lee G, Ali ES, Saathoff MR, Park CH, Savchuk S, Baisiwala S, Miska J, Lesniak MS, James CD, Stupp R, Kumthekar P, Horbinski CM, Ben-Sahra I, Ahmed AU
Brain : a journal of neurology 2021 May 7;144(4):1230-1246

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Oxidative stress induced by NOX2 contributes to neuropathic pain via plasma membrane translocation of PKCε in rat dorsal root ganglion neurons.

Xu J, Wu S, Wang J, Wang J, Yan Y, Zhu M, Zhang D, Jiang C, Liu T
Journal of neuroinflammation 2021 May 6;18(1):106

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Redd1 knockdown prevents doxorubicin-induced cardiac senescence.

Huang P, Bai L, Liu L, Fu J, Wu K, Liu H, Liu Y, Qi B, Qi B
Aging 2021 May 6;13(10):13788-13806

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Circular RNA Calm4 Regulates Hypoxia-Induced Pulmonary Arterial Smooth Muscle Cells Pyroptosis via the Circ-Calm4/miR-124-3p/PDCD6 Axis.

Jiang Y, Liu H, Yu H, Zhou Y, Zhang J, Xin W, Li Y, He S, Ma C, Zheng X, Zhang L, Zhao X, Wu B, Jiang C, Zhu D
Arteriosclerosis, thrombosis, and vascular biology 2021 May 5;41(5):1675-1693

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Evaluation of Stable LifeAct-mRuby2- and LAMP1-NeonGreen Expressing A549 Cell Lines for Investigation of Aspergillus fumigatus Interaction with Pulmonary Cells.

Schiefermeier-Mach N, Moresco V, Geley S, Heinrich L, Lechner L, Oberhauser H, Perkhofer S
International journal of molecular sciences 2021 May 31;22(11)

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High-fat diet impairs ferroptosis and promotes cancer invasiveness via downregulating tumor suppressor ACSL4 in lung adenocarcinoma.

Zhang Y, Li S, Li F, Lv C, Yang QK
Biology direct 2021 May 31;16(1):10

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FKBP52 overexpression accelerates hippocampal-dependent memory impairments in a tau transgenic mouse model.

Criado-Marrero M, Gebru NT, Gould LA, Blazier DM, Vidal-Aguiar Y, Smith TM, Abdelmaboud SS, Shelton LB, Wang X, Dahrendorff J, Beaulieu-Abdelahad D, Dickey CA, Blair LJ
NPJ aging and mechanisms of disease 2021 May 3;7(1):9

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Ribonucleic Acid Export 1 Is a Kinetochore-Associated Protein That Participates in Chromosome Alignment in Mouse Oocytes.

Chen F, Jiao XF, Meng F, Wang YS, Ding ZM, Miao YL, Xiong JJ, Huo LJ
International journal of molecular sciences 2021 May 3;22(9)

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Effect of circular RNA, mmu_circ_0000296, on neuronal apoptosis in chronic cerebral ischaemia via the miR-194-5p/Runx3/Sirt1 axis.

Huang K, Yang C, Zheng J, Liu X, Liu J, Che D, Xue Y, An P, Wang D, Ruan X, Yu B
Cell death discovery 2021 May 29;7(1):124

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Oocyte-secreted factors strongly stimulate sFRP4 expression in human cumulus cells.

Esfandyari S, Winston NJ, Fierro MA, Scoccia H, Stocco C
Molecular human reproduction 2021 May 29;27(6)

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Vertebrate cells differentially interpret ciliary and extraciliary cAMP.

Truong ME, Bilekova S, Choksi SP, Li W, Bugaj LJ, Xu K, Reiter JF
Cell 2021 May 27;184(11):2911-2926.e18

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Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells.

Le Vasseur M, Friedman J, Jost M, Xu J, Yamada J, Kampmann M, Horlbeck MA, Salemi MR, Phinney BS, Weissman JS, Nunnari J
eLife 2021 May 26;10

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Evaluation of the nephrotoxicity and safety of low-dose aristolochic acid, extending to the use of Xixin (Asurum), by determination of methylglyoxal and d-lactate.

Lin CE, Lin PY, Yang WC, Huang YS, Lin TY, Chen CM, Chen HS, Lee JA, Chen SM
Journal of ethnopharmacology 2021 May 23;272:113945

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Downregulation of CD151 restricts VCAM-1 mediated leukocyte infiltration to reduce neurobiological injuries after experimental stroke.

Gao C, Jia W, Xu W, Wu Q, Wu J
Journal of neuroinflammation 2021 May 22;18(1):118

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Maternal folic acid supplementation prevents autistic behaviors in a rat model induced by prenatal exposure to valproic acid.

Di Y, Li Z, Li J, Cheng Q, Zheng Q, Zhai C, Kang M, Wei C, Lan J, Fan J, Ren W, Tian Y
Food & function 2021 May 21;12(10):4544-4555

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[Luteolin has a significant protective effect against cadmium-induced injury in lung epithelial Beas-2B cells].

Chu N, Zhang X, Chen S, Zhen Q, Wang Y
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2021 May 20;41(5):729-735

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[Curcumin induces human lens epithelial cell apoptosis and cell cycle arrest by inhibiting Wnt/β-catenin signaling pathway].

Zhu M, Cui S, Hao Z, Wang W, Yang Q, Chen C, Wang J, Zhou Q
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2021 May 20;41(5):722-728

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[DJ-1 alleviates oxidative stress injury by activating the Nrf2 pathway in rats with cerebral ischemia-reperfusion injury].

Li L, Peng L, Zhu J, Wu J, Zhao Y
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2021 May 20;41(5):679-686

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Ganoderma lucidum stimulates autophagy-dependent longevity pathways in Caenorhabditis elegans and human cells.

Peng HH, Wu CY, Hsiao YC, Martel J, Ke PY, Chiu CY, Liau JC, Chang IT, Su YH, Ko YF, Young JD, Ojcius DM
Aging 2021 May 20;13(10):13474-13495

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USP18 positively regulates innate antiviral immunity by promoting K63-linked polyubiquitination of MAVS.

Hou J, Han L, Zhao Z, Liu H, Zhang L, Ma C, Yi F, Liu B, Zheng Y, Gao C
Nature communications 2021 May 20;12(1):2970

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The miR-378c-Samd1 circuit promotes phenotypic modulation of vascular smooth muscle cells and foam cells formation in atherosclerosis lesions.

Tian S, Cao Y, Wang J, Bi Y, Zhong J, Meng X, Sun W, Yang R, Gan L, Wang X, Li H, Wang R
Scientific reports 2021 May 18;11(1):10548

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Mir-139-5p inhibits glioma cell proliferation and progression by targeting GABRA1.

Wang L, Liu Y, Yu Z, Gong J, Deng Z, Ren N, Zhong Z, Cai H, Tang Z, Cheng H, Chen S, He Z
Journal of translational medicine 2021 May 17;19(1):213

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LncRNA ZNF674-AS1 regulates granulosa cell glycolysis and proliferation by interacting with ALDOA.

Li D, Wang X, Li G, Dang Y, Zhao S, Qin Y
Cell death discovery 2021 May 16;7(1):107

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Exercise improves lipid droplet metabolism disorder through activation of AMPK-mediated lipophagy in NAFLD.

Li H, Dun Y, Zhang W, You B, Liu Y, Fu S, Qiu L, Cheng J, Ripley-Gonzalez JW, Liu S
Life sciences 2021 May 15;273:119314

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SET8 mitigates hepatic ischemia/reperfusion injury in mice by suppressing MARK4/NLRP3 inflammasome pathway.

Luo Y, Huang Z, Mou T, Pu J, Li T, Li Z, Yang H, Yan P, Wu Z, Wu Q
Life sciences 2021 May 15;273:119286

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Purification, structural characterization, and PCSK9 secretion inhibitory effect of the novel alkali-extracted polysaccharide from Cordyceps militaris.

Wang J, Wang Y, Yang X, Lin P, Liu N, Li X, Zhang B, Guo S
International journal of biological macromolecules 2021 May 15;179:407-417

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Asenapine maleate inhibits angiotensin II-induced proliferation and activation of cardiac fibroblasts via the ROS/TGFβ1/MAPK signaling pathway.

Wu HH, Meng TT, Chen JM, Meng FL, Wang SY, Liu RH, Chen JN, Ning B, Li Y, Su GH
Biochemical and biophysical research communications 2021 May 14;553:172-179

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Hyperactivation of HER2-SHCBP1-PLK1 axis promotes tumor cell mitosis and impairs trastuzumab sensitivity to gastric cancer.

Shi W, Zhang G, Ma Z, Li L, Liu M, Qin L, Yu Z, Zhao L, Liu Y, Zhang X, Qin J, Ye H, Jiang X, Zhou H, Sun H, Jiao Z
Nature communications 2021 May 14;12(1):2812

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trans-Fatty acids promote p53-dependent apoptosis triggered by cisplatin-induced DNA interstrand crosslinks via the Nox-RIP1-ASK1-MAPK pathway.

Hirata Y, Takahashi M, Yamada Y, Matsui R, Inoue A, Ashida R, Noguchi T, Matsuzawa A
Scientific reports 2021 May 14;11(1):10350

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A subcellular map of the human kinome.

Zhang H, Cao X, Tang M, Zhong G, Si Y, Li H, Zhu F, Liao Q, Li L, Zhao J, Feng J, Li S, Wang C, Kaulich M, Wang F, Chen L, Li L, Xia Z, Liang T, Lu H, Feng XH, Zhao B
eLife 2021 May 14;10

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Berberine-photodynamic therapy sensitizes melanoma cells to cisplatin-induced apoptosis through ROS-mediated P38 MAPK pathways.

Wang X, Gong Q, Song C, Fang J, Yang Y, Liang X, Huang X, Liu J
Toxicology and applied pharmacology 2021 May 1;418:115484

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High fat suppresses SOD1 activity by reducing copper chaperone for SOD1 associated with neurodegeneration and memory decline.

Lu P, Yan HJ, Yang C, Feng WC, Hu F, Wu YY, Sun WW, Gao MM, Long YS
Life sciences 2021 May 1;272:119243

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Short-term but not long-term high fat diet feeding protects against pressure overload-induced heart failure through activation of mitophagy.

Tan Y, Li M, Wu G, Lou J, Feng M, Xu J, Zhou J, Zhang P, Yang H, Dong L, Li J, Zhang X, Gao F
Life sciences 2021 May 1;272:119242

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6-Gingerol attenuates ventilator-induced lung injury via anti-inflammation and antioxidative stress by modulating the PPARγ/NF-κBsignalling pathway in rats.

Hong W, Zhi FX, Kun TH, Hua FJ, Huan Ling L, Fang F, Wen C, Jie W, Yang LC
International immunopharmacology 2021 Mar;92:107367

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Total glycosides from stems of Cistanche tubulosa alleviate depression-like behaviors: bidirectional interaction of the phytochemicals and gut microbiota.

Fan L, Peng Y, Wang J, Ma P, Zhao L, Li X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Mar;83:153471

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Androgen Receptor Stimulates Hexokinase 2 and Induces Glycolysis by PKA/CREB Signaling in Hepatocellular Carcinoma.

Sun RF, Zhao CY, Chen S, Yu W, Zhou MM, Gao CR
Digestive diseases and sciences 2021 Mar;66(3):802-813

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Circadian clock genes promote glioma progression by affecting tumour immune infiltration and tumour cell proliferation.

Wang Z, Su G, Dai Z, Meng M, Zhang H, Fan F, Liu Z, Zhang L, Weygant N, He F, Fang N, Zhang L, Cheng Q
Cell proliferation 2021 Mar;54(3):e12988

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Nbs1-mediated DNA damage repair pathway regulates haematopoietic stem cell development and embryonic haematopoiesis.

Chen Y, Sun J, Ju Z, Wang ZQ, Li T
Cell proliferation 2021 Mar;54(3):e12972

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MiR-520a-3p inhibits malignant progression of epithelial ovarian cancer by targeting SUV39H1 expression.

Li J, Shao W, Zhao J
Human cell 2021 Mar;34(2):570-578

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Oncogenic AURKA-enhanced N(6)-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells.

Peng F, Xu J, Cui B, Liang Q, Zeng S, He B, Zou H, Li M, Zhao H, Meng Y, Chen J, Liu B, Lv S, Chu P, An F, Wang Z, Huang J, Zhan Y, Liao Y, Lu J, Xu L, Zhang J, Sun Z, Li Z, Wang F, Lam EW, Liu Q
Cell research 2021 Mar;31(3):345-361

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Chondrocyte ferroptosis contribute to the progression of osteoarthritis.

Yao X, Sun K, Yu S, Luo J, Guo J, Lin J, Wang G, Guo Z, Ye Y, Guo F
Journal of orthopaedic translation 2021 Mar;27:33-43

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miR-130b-3p regulates M1 macrophage polarization via targeting IRF1.

Guo Q, Zhu X, Wei R, Zhao L, Zhang Z, Yin X, Zhang Y, Chu C, Wang B, Li X
Journal of cellular physiology 2021 Mar;236(3):2008-2022

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Arsenite induce neurotoxicity of common carp: Involvement of blood brain barrier, apoptosis and autophagy, and subsequently relieved by zinc (Ⅱ) supplementation.

Wang Y, Zhao H, Liu Y, Guo M, Tian Y, Huang P, Xing M
Aquatic toxicology (Amsterdam, Netherlands) 2021 Mar;232:105765

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Apoptosis inhibition is involved in improvement of sevoflurane-induced cognitive impairment following normobaric hyperoxia preconditioning in aged rats.

Wang Y, Yin CP, Tai YL, Zhao ZJ, Hou ZY, Wang QJ
Experimental and therapeutic medicine 2021 Mar;21(3):203

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Regulation of ARL2 in colorectal cancer cell proliferation and tumorigenicity, and its negative association with AXL.

Pang X, Wang Y, Miao B, Fei S, Chen W
Oncology letters 2021 Mar;21(3):196

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Three phytosterols from sweet potato inhibit MCF7-xenograft-tumor growth through modulating gut microbiota homeostasis and SCFAs secretion.

Han B, Jiang P, Jiang L, Li X, Ye X
Food research international (Ottawa, Ont.) 2021 Mar;141:110147

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d-Mannose suppresses osteoarthritis development in vivo and delays IL-1β-induced degeneration in vitro by enhancing autophagy activated via the AMPK pathway.

Lin Z, Miao J, Zhang T, He M, Zhou X, Zhang H, Gao Y, Bai L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Mar;135:111199

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Gasdermin D Protects Mouse Podocytes Against High-Glucose-Induced Inflammation and Apoptosis via the C-Jun N-Terminal Kinase (JNK) Pathway.

Li H, Zhao K, Li Y
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 9;27:e928411

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Plumbagin, a Biomolecule with (Anti)Osteoclastic Properties.

Sultanli S, Ghumnani S, Ashma R, Kubatzky KF
International journal of molecular sciences 2021 Mar 9;22(5)

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Expression of Talin-1 in endometriosis and its possible role in pathogenesis.

Tang X, Li Q, Li L, Jiang J
Reproductive biology and endocrinology : RB&E 2021 Mar 9;19(1):42

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lncRNA GCAT1 is involved in premature ovarian insufficiency by regulating p27 translation in GCs via competitive binding to PTBP1.

Li D, Wang X, Dang Y, Zhang X, Zhao S, Lu G, Chan WY, Leung PCK, Qin Y
Molecular therapy. Nucleic acids 2021 Mar 5;23:132-141

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Combining combretastatin A4 phosphate with ginsenoside Rd synergistically inhibited hepatocellular carcinoma by reducing HIF-1α via PI3K/AKT/mTOR signalling pathway.

Yang X, Gao M, Miao M, Jiang C, Zhang D, Yin Z, Ni Y, Chen J, Zhang J
The Journal of pharmacy and pharmacology 2021 Mar 4;73(2):263-271

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PUMA facilitates EMI1-promoted cytoplasmic Rad51 ubiquitination and inhibits DNA repair in stem and progenitor cells.

Kang JW, Zhan Z, Ji G, Sang Y, Zhou D, Li Y, Feng H, Cheng T
Signal transduction and targeted therapy 2021 Mar 31;6(1):129

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MYC promotes cancer progression by modulating m(6) A modifications to suppress target gene translation.

Wu G, Suo C, Yang Y, Shen S, Sun L, Li ST, Zhou Y, Yang D, Wang Y, Cai Y, Wang N, Zhang H, Yang YG, Cao J, Gao P
EMBO reports 2021 Mar 3;22(3):e51519

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The CREB/KMT5A complex regulates PTP1B to modulate high glucose-induced endothelial inflammatory factor levels in diabetic nephropathy.

Huang T, Li X, Wang F, Lu L, Hou W, Zhu M, Miao C
Cell death & disease 2021 Mar 29;12(4):333

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Profiling PRMT methylome reveals roles of hnRNPA1 arginine methylation in RNA splicing and cell growth.

Li WJ, He YH, Yang JJ, Hu GS, Lin YA, Ran T, Peng BL, Xie BL, Huang MF, Gao X, Huang HH, Zhu HH, Ye F, Liu W
Nature communications 2021 Mar 29;12(1):1946

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Angiomotin Counteracts the Negative Regulatory Effect of Host WWOX on Viral PPxY-Mediated Egress.

Liang J, Ruthel G, Sagum CA, Bedford MT, Sidhu SS, Sudol M, Jaladanki CK, Fan H, Freedman BD, Harty RN
Journal of virology 2021 Mar 25;95(8)

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Hispidulin inhibits proliferation, migration, and invasion by promoting autophagy via regulation of PPARγ activation in prostate cancer cells and xenograft models.

Wang Y, Guo S, Jia Y, Yu X, Mou R, Li X
Bioscience, biotechnology, and biochemistry 2021 Mar 24;85(4):786-797

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Inhibition of lipogenesis and induction of apoptosis by valproic acid in prostate cancer cells via the C/EBPα/SREBP-1 pathway.

Pang B, Zhang J, Zhang X, Yuan J, Shi Y, Qiao L
Acta biochimica et biophysica Sinica 2021 Mar 2;53(3):354-364

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Effects of transforming growth factor-β1 on odontoblastic differentiation in dental papilla cells is determined by IPO7 expression level.

Zhang Y, Zhang H, Yuan G, Yang G
Biochemical and biophysical research communications 2021 Mar 19;545:105-111

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hPER3 promotes adipogenesis via hHSP90AA1-mediated inhibition of Notch1 pathway.

Wan X, Zhu L, Zhao L, Peng L, Xiong J, Yang W, Yuan J, Liang F, Zhang K, Chen K
Cell death & disease 2021 Mar 19;12(4):301

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Identifying SLC27A5 as a potential prognostic marker of hepatocellular carcinoma by weighted gene co-expression network analysis and in vitro assays.

Zhang F, Xue M, Jiang X, Yu H, Qiu Y, Yu J, Yang F, Bao Z
Cancer cell international 2021 Mar 17;21(1):174

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PEG-GO@XN nanocomposite suppresses breast cancer metastasis via inhibition of mitochondrial oxidative phosphorylation and blockade of epithelial-to-mesenchymal transition.

Zhang J, Yan L, Wei P, Zhou R, Hua C, Xiao M, Tu Y, Gu Z, Wei T
European journal of pharmacology 2021 Mar 15;895:173866

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PCGF3 promotes the proliferation and migration of non-small cell lung cancer cells via the PI3K/AKT signaling pathway.

Hu Y, Cheng Y, Jiang X, Zhang Y, Wang H, Ren H, Xu Y, Jiang J, Wang Q, Su H, Zhang B, Qiu X
Experimental cell research 2021 Mar 15;400(2):112496

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The Effect of Hispidulin, a Flavonoid from Salvia plebeia, on Human Nasopharyngeal Carcinoma CNE-2Z Cell Proliferation, Migration, Invasion, and Apoptosis.

Dai Y, Sun X, Li B, Ma H, Wu P, Zhang Y, Zhu M, Li HM, Qin M, Wu CZ
Molecules (Basel, Switzerland) 2021 Mar 14;26(6)

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Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.

Han D, Xu Y, Peng WP, Feng F, Wang Z, Gu C, Zhou X
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 12;27:e928547

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Gastrodin ameliorates learning and memory impairment in rats with vascular dementia by promoting autophagy flux via inhibition of the Ca(2+)/CaMKII signal pathway.

Chen TT, Zhou X, Xu YN, Li Y, Wu XY, Xiang Q, Fu LY, Hu XX, Tao L, Shen XC
Aging 2021 Mar 10;13(7):9542-9565

---

Cytotoxicity mechanisms of plumbagin in drug-resistant tongue squamous cell carcinoma.

Xue D, Zhou X, Qiu J
The Journal of pharmacy and pharmacology 2021 Mar 1;73(1):98-109

---

The deubiquitylase USP9X controls ribosomal stalling.

Clancy A, Heride C, Pinto-Fernández A, Elcocks H, Kallinos A, Kayser-Bricker KJ, Wang W, Smith V, Davis S, Fessler S, McKinnon C, Katz M, Hammonds T, Jones NP, O'Connell J, Follows B, Mischke S, Caravella JA, Ioannidis S, Dinsmore C, Kim S, Behrens A, Komander D, Kessler BM, Urbé S, Clague MJ
The Journal of cell biology 2021 Mar 1;220(3)

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SZB120 Exhibits Immunomodulatory Effects by Targeting eIF2α to Suppress Th17 Cell Differentiation.

Chen L, Bai J, Peng D, Gao Y, Cai X, Zhang J, Tang S, Niu L, Sun Y, Lou F, Zhou H, Yin Q, Wang Z, Sun L, Du X, Xu Z, Wang H, Li Q, Wang H
Journal of immunology (Baltimore, Md. : 1950) 2021 Mar 1;206(5):953-962

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Melatonin inhibits vascular endothelial cell pyroptosis by improving mitochondrial function via up-regulation and demethylation of UQCRC1.

Zeng J, Tao J, Xia L, Zeng Z, Chen J, Wang Z, Meng J, Liu L
Biochemistry and cell biology = Biochimie et biologie cellulaire 2021 Jun;99(3):339-347

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A novel peptide promotes human trophoblast proliferation and migration through PI3K/Akt/mTOR signaling pathway.

Ling L, Yuan X, Liu X, Pei W, Li R
Annals of translational medicine 2021 Jun;9(12):981

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Ninjinyoeito improves anxiety behavior in neuropeptide Y deficient zebrafish.

Kawabe M, Hayashi A, Komatsu M, Inui A, Shiozaki K
Neuropeptides 2021 Jun;87:102136

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Interleukin-24 as a Pulmonary Target Cytokine in Bronchopulmonary Dysplasia.

Gao R, Li Z, Ai D, Ma J, Chen C, Liu X
Cell biochemistry and biophysics 2021 Jun;79(2):311-320

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Promoterless, Nuclease-Free Genome Editing Confers a Growth Advantage for Corrected Hepatocytes in Mice With Methylmalonic Acidemia.

Chandler RJ, Venturoni LE, Liao J, Hubbard BT, Schneller JL, Hoffmann V, Gordo S, Zang S, Ko CW, Chau N, Chiang K, Kay MA, Barzel A, Venditti CP
Hepatology (Baltimore, Md.) 2021 Jun;73(6):2223-2237

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NCOA4-mediated ferritinophagy promoted inflammatory responses in periodontitis.

Guo W, Zhao Y, Li H, Lei L
Journal of periodontal research 2021 Jun;56(3):523-534

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Sodium sulfite causes gastric mucosal cell death by inducing oxidative stress.

Oshimo M, Nakashima F, Kai K, Matsui H, Shibata T, Akagawa M
Free radical research 2021 Jun;55(6):731-743

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Golgi phosphoprotein 3 promotes the proliferation of gallbladder carcinoma cells via regulation of the NLRP3 inflammasome.

Zhu Z, Zhu Q, Cai D, Chen L, Xie W, Bai Y, Luo K
Oncology reports 2021 Jun;45(6)

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FMR1/circCHAF1A/miR-211-5p/HOXC8 feedback loop regulates proliferation and tumorigenesis via MDM2-dependent p53 signaling in GSCs.

Jiang Y, Wang Z, Ying C, Hu J, Zeng T, Gao L
Oncogene 2021 Jun;40(24):4094-4110

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SMAR1 attenuates the stemness of osteosarcoma cells via through suppressing ABCG2 transcriptional activity.

Xu H, Liu T, Li W, Yao Q
Environmental toxicology 2021 Jun;36(6):1090-1098

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Small Interfering RNA Targeting DMP1 Protects Mice Against Blood-Brain Barrier Disruption and Brain Injury After Intracerebral Hemorrhage.

Shu Y, Huang J, Gao M, Gan S, Zhu S, Xu S, Yang Z, Liao Y, Lu W
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2021 Jun;30(6):105760

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Cellular microRNAs influence replication of H3N2 canine influenza virus in infected cells.

Xie X, Pang M, Liang S, Lin Y, Zhao Y, Qiu D, Liu J, Dong Y, Liu Y
Veterinary microbiology 2021 Jun;257:109083

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Sparstolonin B exerts beneficial effects on prostate cancer by acting on the reactive oxygen species-mediated PI3K/AKT pathway.

Liu S, Hu J, Shi C, Sun L, Yan W, Song Y
Journal of cellular and molecular medicine 2021 Jun;25(12):5511-5524

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Fructose-1,6-bisphosphatase aggravates oxidative stress-induced apoptosis in asthma by suppressing the Nrf2 pathway.

Hu J, Wang J, Li C, Shang Y
Journal of cellular and molecular medicine 2021 Jun;25(11):5001-5014

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Phgdh serves a protective role in Il‑1β induced chondrocyte inflammation and oxidative‑stress damage.

Huang H, Liu K, Ou H, Qian X, Wan J
Molecular medicine reports 2021 Jun;23(6)

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Exploration of the hepatoprotective effect and mechanism of magnesium isoglycyrrhizinate in mice with arsenic trioxide‑induced acute liver injury.

Liu M, Zheng B, Liu P, Zhang J, Chu X, Dong C, Shi J, Liang Y, Chu L, Liu Y, Han X
Molecular medicine reports 2021 Jun;23(6)

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Resveratrol sensitizes A549 cells to irradiation damage via suppression of store-operated calcium entry with Orai1 and STIM1 downregulation.

Lele W, Lei L, Liting Q
Experimental and therapeutic medicine 2021 Jun;21(6):587

---

Differential expression of protein disulfide isomerase (PDI) in regulating endometrial receptivity in humans.

Fernando SR, Kottawatta KSA, Jiang L, Chen X, Cheng KW, Wong BP, Ng EH, Yeung WS, Lee KF
Reproductive biology 2021 Jun;21(2):100498

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miR-29a-3p-dependent COL3A1 and COL5A1 expression reduction assists sulforaphane to inhibit gastric cancer progression.

Han S, Wang Z, Liu J, Wang HD, Yuan Q
Biochemical pharmacology 2021 Jun;188:114539

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RRx-001 ameliorates inflammatory diseases by acting as a potent covalent NLRP3 inhibitor.

Chen Y, He H, Lin B, Chen Y, Deng X, Jiang W, Zhou R
Cellular & molecular immunology 2021 Jun;18(6):1425-1436

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Signal-regulatory protein alpha is an anti-viral entry factor targeting viruses using endocytic pathways.

Sarute N, Cheng H, Yan Z, Salas-Briceno K, Richner J, Rong L, Ross SR
PLoS pathogens 2021 Jun;17(6):e1009662

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SNX-3 mediates retromer-independent tubular endosomal recycling by opposing EEA-1-facilitated trafficking.

Tian Y, Kang Q, Shi X, Wang Y, Zhang N, Ye H, Xu Q, Xu T, Zhang R
PLoS genetics 2021 Jun;17(6):e1009607

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Paricalcitol inhibits oxidative stress-induced cell senescence of the bile duct epithelium dependent on modulating Sirt1 pathway in cholestatic mice.

Jia R, Yang F, Yan P, Ma L, Yang L, Li L
Free radical biology & medicine 2021 Jun;169:158-168

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A novel gene therapy for neurodegenerative Lafora disease via EPM2A-loaded DLinDMA lipoplexes.

Vemana HP, Saraswat A, Bhutkar S, Patel K, Dukhande VV
Nanomedicine (London, England) 2021 Jun;16(13):1081-1095

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Natural molecule Munronoid I attenuates LPS-induced acute lung injury by promoting the K48-linked ubiquitination and degradation of TAK1.

Ma X, Li X, Di Q, Zhao X, Zhang R, Xiao Y, Sun P, Tang H, Quan J, Xiao W, Chen W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111543

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Tumor cell membrane-based peptide delivery system targeting the tumor microenvironment for cancer immunotherapy and diagnosis.

Meng X, Wang J, Zhou J, Tian Q, Qie B, Zhou G, Duan W, Zhu Y
Acta biomaterialia 2021 Jun;127:266-275

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Long non-coding RNA muskelin 1 antisense RNA (MKLN1-AS) is a potential diagnostic and prognostic biomarker and therapeutic target for hepatocellular carcinoma.

Guo C, Zhou S, Yi W, Yang P, Li O, Liu J, Peng C
Experimental and molecular pathology 2021 Jun;120:104638

---

Upregulation of ZHX2 predicts poor prognosis and is correlated with immune infiltration in gastric cancer.

Cheng A, Guo X, Dai X, Wang Z
FEBS open bio 2021 Jun;11(6):1785-1798

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Effect of SOCS3 on apoptosis of human trophoblasts via adjustment of the JAK2/STAT3 signaling pathway in preterm birth.

Yin Y, Qu L, Zhu D, Wu Y, Zhou X
Translational pediatrics 2021 Jun;10(6):1637-1646

---

CDK5 positively regulates Notch1 signaling in pancreatic cancer cells by phosphorylation.

Chu Q, Wang L, Zhang J, Wang W, Wang Y
Cancer medicine 2021 Jun;10(11):3689-3699

---

PBRM1 Cooperates with YTHDF2 to Control HIF-1α Protein Translation.

Shmakova A, Frost M, Batie M, Kenneth NS, Rocha S
Cells 2021 Jun 8;10(6)

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Multilevel regulation of Wnt signaling by Zic2 in colon cancer due to mutation of β-catenin.

Xu Z, Zheng J, Chen Z, Guo J, Li X, Wang X, Qu C, Yuan L, Cheng C, Sun X, Yu J
Cell death & disease 2021 Jun 7;12(6):584

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The combination of CUDC-907 and gilteritinib shows promising in vitro and in vivo antileukemic activity against FLT3-ITD AML.

Qiao X, Ma J, Knight T, Su Y, Edwards H, Polin L, Li J, Kushner J, Dzinic SH, White K, Wang J, Lin H, Wang Y, Wang L, Wang G, Taub JW, Ge Y
Blood cancer journal 2021 Jun 7;11(6):111

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Hypericin-mediated photodynamic therapy inhibits growth of colorectal cancer cells via inducing S phase cell cycle arrest and apoptosis.

Hu J, Song J, Tang Z, Wei S, Chen L, Zhou R
European journal of pharmacology 2021 Jun 5;900:174071

---

Cisplatin remodels the tumor immune microenvironment via the transcription factor EB in ovarian cancer.

Liu W, Wang Y, Xie Y, Dai T, Fan M, Li C, Zou Y
Cell death discovery 2021 Jun 5;7(1):136

---

The benzoate plant metabolite ethyl gallate prevents cellular- and vascular-lipid accumulation in experimental models of atherosclerosis.

Liu W, Liu J, Xing S, Pan X, Wei S, Zhou M, Li Z, Wang L, Bielicki JK
Biochemical and biophysical research communications 2021 Jun 4;556:65-71

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Alisol A 24-acetate protects against brain microvascular endothelial cells injury through inhibiting miR-92a-3p/tight junctions axis.

Lu L, Lu T, Shen J, Lv X, Wei W, Wang H, Xue X
Aging 2021 Jun 4;13(11):15353-15365

---

Formin-like protein 2 promotes cell proliferation by a p27-related mechanism in human breast cancer cells.

Jiao X, Wang B, Feng C, Song S, Tian B, Zhou C, Gao X, Sun W, Liu P
BMC cancer 2021 Jun 30;21(1):760

---

Purification, characterization and anti-atherosclerotic effects of the polysaccharides from the fruiting body of Cordyceps militaris.

Yang X, Lin P, Wang J, Liu N, Yin F, Shen N, Guo S
International journal of biological macromolecules 2021 Jun 30;181:890-904

---

Self-stabilizing regulation of deubiquitinating enzymes in an enzymatic activity-dependent manner.

Hou Z, Shi W, Feng J, Wang W, Zheng E, Lin H, Yu C, Li L
International journal of biological macromolecules 2021 Jun 30;181:1081-1091

---

Breast tumor stiffness instructs bone metastasis via maintenance of mechanical conditioning.

Watson AW, Grant AD, Parker SS, Hill S, Whalen MB, Chakrabarti J, Harman MW, Roman MR, Forte BL, Gowan CC, Castro-Portuguez R, Stolze LK, Franck C, Cusanovich DA, Zavros Y, Padi M, Romanoski CE, Mouneimne G
Cell reports 2021 Jun 29;35(13):109293

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Neu1 deficiency induces abnormal emotional behavior in zebrafish.

Ikeda A, Komamizu M, Hayashi A, Yamasaki C, Okada K, Kawabe M, Komatsu M, Shiozaki K
Scientific reports 2021 Jun 29;11(1):13477

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Thymosin β4 reverses phenotypic polarization of glial cells and cognitive impairment via negative regulation of NF-κB signaling axis in APP/PS1 mice.

Wang M, Feng LR, Li ZL, Ma KG, Chang KW, Chen XL, Yang PB, Ji SF, Ma YB, Han H, Ruganzua JB, Yang WN, Qian YH
Journal of neuroinflammation 2021 Jun 28;18(1):146

---

The Anti-Tumor Effect and Underlying Apoptotic Mechanism of Ginsenoside Rk1 and Rg5 in Human Liver Cancer Cells.

Chen C, Lv Q, Li Y, Jin YH
Molecules (Basel, Switzerland) 2021 Jun 27;26(13)

---

DUSP1 overexpression attenuates renal tubular mitochondrial dysfunction by restoring Parkin-mediated mitophagy in diabetic nephropathy.

Lu C, Wu B, Liao Z, Xue M, Zou Z, Feng J, Sheng J
Biochemical and biophysical research communications 2021 Jun 25;559:141-147

---

LncRNA CARMN overexpression promotes prognosis and chemosensitivity of triple negative breast cancer via acting as miR143-3p host gene and inhibiting DNA replication.

Sheng X, Dai H, Du Y, Peng J, Sha R, Yang F, Zhou L, Lin Y, Xu S, Wu Y, Yin W, Lu J
Journal of experimental & clinical cancer research : CR 2021 Jun 23;40(1):205

---

Binding of Benzo[a]pyrene Alters the Bioreactivity of Fine Biochar Particles toward Macrophages Leading to Deregulated Macrophagic Defense and Autophagy.

Ma J, Liu X, Yang Y, Qiu J, Dong Z, Ren Q, Zuo YY, Xia T, Chen W, Liu S
ACS nano 2021 Jun 22;15(6):9717-9731

---

LINC00842 inactivates transcription co-regulator PGC-1α to promote pancreatic cancer malignancy through metabolic remodelling.

Huang X, Pan L, Zuo Z, Li M, Zeng L, Li R, Ye Y, Zhang J, Wu G, Bai R, Zhuang L, Wei L, Zheng Y, Su J, Deng J, Deng S, Zhang S, Zhu S, Che X, Wang C, Wu C, Chen R, Lin D, Zheng J
Nature communications 2021 Jun 22;12(1):3830

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LINC_00355 promotes gastric cancer progression by upregulating PHF19 expression through sponging miR-15a-5p.

Zhang J, Lv W, Liu Y, Fu W, Chen B, Ma Q, Gao X
BMC cancer 2021 Jun 2;21(1):657

---

Colorectal cancer cells utilize autophagy to maintain mitochondrial metabolism for cell proliferation under nutrient stress.

Devenport SN, Singhal R, Radyk MD, Taranto JG, Kerk SA, Chen B, Goyert JW, Jain C, Das NK, Oravecz-Wilson K, Zhang L, Greenson JK, Chen YE, Soleimanpour SA, Reddy P, Lyssiotis CA, Shah YM
JCI insight 2021 Jun 17;6(14)

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Isorhamnetin Promotes Estrogen Biosynthesis and Proliferation in Porcine Granulosa Cells via the PI3K/Akt Signaling Pathway.

Li X, Chen H, Zhang Z, Xu D, Duan J, Li X, Yang L, Hua R, Cheng J, Li Q
Journal of agricultural and food chemistry 2021 Jun 16;69(23):6535-6542

---

Protective effect of scorpion venom heat-resistant synthetic peptide against PM(2.5)-induced microglial polarization via TLR4-mediated autophagy activating PI3K/AKT/NF-κB signaling pathway.

Xu X, Xu H, Ren F, Huang L, Xu J, Li F
Journal of neuroimmunology 2021 Jun 15;355:577567

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HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron.

Singhal R, Mitta SR, Das NK, Kerk SA, Sajjakulnukit P, Solanki S, Andren A, Kumar R, Olive KP, Banerjee R, Lyssiotis CA, Shah YM
The Journal of clinical investigation 2021 Jun 15;131(12)

---

Aerobic Exercise Improves Mitochondrial Function in Sarcopenia Mice Through Sestrin2 in an AMPKα2-Dependent Manner.

Liu S, Yu C, Xie L, Niu Y, Fu L
The journals of gerontology. Series A, Biological sciences and medical sciences 2021 Jun 14;76(7):1161-1168

---

LncRSPH9-4 Facilitates Meningitic Escherichia coli-Caused Blood-Brain Barrier Disruption via miR-17-5p/MMP3 Axis.

Xu B, Yang R, Fu J, Yang B, Chen J, Tan C, Chen H, Wang X
International journal of molecular sciences 2021 Jun 14;22(12)

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The engineered expression of secreted HSPB5-Fc in CHO cells exhibits cytoprotection in vitro.

Li J, Yu J, Xue W, Huang H, Yan L, Sang F, An S, Zhang J, Wang M, Zhang J, Li H, Cui X, He J, Hu Y
BMC biotechnology 2021 Jun 14;21(1):39

---

Protective effects of 4-octyl itaconate against inflammatory response in angiotensin II-induced oxidative stress in human primary retinal pigment epithelium.

Fu X, Wu M, Zhou X
Biochemical and biophysical research communications 2021 Jun 11;557:77-84

---

Protective Effects of Bone Marrow Mesenchymal Stem Cells (BMMSCS) Combined with Normothermic Machine Perfusion on Liver Grafts Donated After Circulatory Death via Reducing the Ferroptosis of Hepatocytes.

Sun D, Yang L, Zheng W, Cao H, Wu L, Song H
Medical science monitor : international medical journal of experimental and clinical research 2021 Jun 11;27:e930258

---

Central nervous system-targeted adeno-associated virus gene therapy in methylmalonic acidemia.

May FJ, Head PE, Venturoni LE, Chandler RJ, Venditti CP
Molecular therapy. Methods & clinical development 2021 Jun 11;21:765-776

---

LncRNA CTD-2528L19.6 prevents the progression of IPF by alleviating fibroblast activation.

Chen T, Guo Y, Wang J, Ai L, Ma L, He W, Li Z, Yu X, Li J, Fan X, Gu Y, Liang H
Cell death & disease 2021 Jun 10;12(6):600

---

Resveratrol and its derivative pterostilbene ameliorate intestine injury in intrauterine growth-retarded weanling piglets by modulating redox status and gut microbiota.

Chen Y, Zhang H, Chen Y, Jia P, Ji S, Zhang Y, Wang T
Journal of animal science and biotechnology 2021 Jun 10;12(1):70

---

Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance.

Liu Y, Liang G, Xu H, Dong W, Dong Z, Qiu Z, Zhang Z, Li F, Huang Y, Li Y, Wu J, Yin S, Zhang Y, Guo P, Liu J, Xi JJ, Jiang P, Han D, Yang CG, Xu MM
Cell metabolism 2021 Jun 1;33(6):1221-1233.e11

---

Hyaluronic acid/polyethyleneimine nanoparticles loaded with copper ion and disulfiram for esophageal cancer.

Xu R, Zhang K, Liang J, Gao F, Li J, Guan F
Carbohydrate polymers 2021 Jun 1;261:117846

---

Galectin-9 Targets NLRP3 for Autophagic Degradation to Limit Inflammation.

Wang W, Qin Y, Song H, Wang L, Jia M, Zhao C, Gong M, Zhao W
Journal of immunology (Baltimore, Md. : 1950) 2021 Jun 1;206(11):2692-2699

---

Butyrate enhances CPT1A activity to promote fatty acid oxidation and iTreg differentiation.

Hao F, Tian M, Zhang X, Jin X, Jiang Y, Sun X, Wang Y, Peng P, Liu J, Xia C, Feng Y, Wei M
Proceedings of the National Academy of Sciences of the United States of America 2021 Jun 1;118(22)

---

25-Hydroxycholesterol mitigates hepatic ischemia reperfusion injury via mediating mitophagy.

Cao Q, Luo J, Xiong Y, Liu Z, Ye Q
International immunopharmacology 2021 Jul;96:107643

---

Targeting TSP-1 decreased periodontitis by attenuating extracellular matrix degradation and alveolar bone destruction.

Liu X, Jin J, Liu Y, Shen Z, Zhao R, Ou L, Xing T
International immunopharmacology 2021 Jul;96:107618

---

Pirfenidone mediates cigarette smoke extract induced inflammation and oxidative stress in vitro and in vivo.

Ma Y, Luo L, Liu X, Li H, Zeng Z, He X, Zhan Z, Chen Y
International immunopharmacology 2021 Jul;96:107593

---

A neutral polysaccharide from Ophiocordyceps lanpingensis restrains cisplatin-induced nephrotoxicity.

Zhou S, Zhou Y, Yu J, Jiang L, Xiang Y, Wang J, Du Y, Cui X, Ge F
Food science & nutrition 2021 Jul;9(7):3602-3616

---

YAP/TEAD4-induced KIF4A contributes to the progression and worse prognosis of esophageal squamous cell carcinoma.

Li Y, Zhu X, Yang M, Wang Y, Li J, Fang J, Guo W, Ma S, Guan F
Molecular carcinogenesis 2021 Jul;60(7):440-454

---

Thioredoxin-1 Rescues MPP(+)/MPTP-Induced Ferroptosis by Increasing Glutathione Peroxidase 4.

Bai L, Yan F, Deng R, Gu R, Zhang X, Bai J
Molecular neurobiology 2021 Jul;58(7):3187-3197

---

miR-671-5p Attenuates Neuroinflammation via Suppressing NF-κB Expression in an Acute Ischemic Stroke Model.

Deng L, Guo Y, Liu J, Wang X, Chen S, Wang Q, Rao J, Wang Y, Zuo T, Hu Q, Zhao X, Dong Z
Neurochemical research 2021 Jul;46(7):1801-1813

---

DHCR24 Knockdown Lead to Hyperphosphorylation of Tau at Thr181, Thr231, Ser262, Ser396, and Ser422 Sites by Membrane Lipid-Raft Dependent PP2A Signaling in SH-SY5Y Cells.

Qi Z, Zhang Y, Yao K, Zhang M, Xu Y, Zhang J, Bai X, Zu H
Neurochemical research 2021 Jul;46(7):1627-1640

---

Hawthorn polyphenols, D-chiro-inositol, and epigallocatechin gallate exert a synergistic hypoglycemic effect.

Xin C, Zhao M, Wang J, Wang Z
Journal of food biochemistry 2021 Jul;45(7):e13771

---

EZH2 regulates expression of FOXC1 by mediating H3K27me3 in breast cancers.

Zheng XJ, Li W, Yi J, Liu JY, Ren LW, Zhu XM, Liu SW, Wang JH, Du GH
Acta pharmacologica Sinica 2021 Jul;42(7):1171-1179

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The role of the HIF-1α/ALYREF/PKM2 axis in glycolysis and tumorigenesis of bladder cancer.

Wang JZ, Zhu W, Han J, Yang X, Zhou R, Lu HC, Yu H, Yuan WB, Li PC, Tao J, Lu Q, Wei JF, Yang H
Cancer communications (London, England) 2021 Jul;41(7):560-575

---

Sestrin2 protects against traumatic brain injury by reinforcing the activation of Nrf2 signaling.

Liu X, Li M, Zhu J, Huang W, Song J
Human & experimental toxicology 2021 Jul;40(7):1095-1111

---

Targeted radioimmunotherapy with the iodine-131-labeled caerin 1.1 peptide for human anaplastic thyroid cancer in nude mice.

Lin R, Ma B, Liu N, Zhang L, He T, Liu X, Chen T, Liu W, Liang Y, Wang T, Ni G, Liu X, Yang N, Zhang J, Yuan J
Annals of nuclear medicine 2021 Jul;35(7):811-822

---

Hepcidin sequesters iron to sustain nucleotide metabolism and mitochondrial function in colorectal cancer epithelial cells.

Schwartz AJ, Goyert JW, Solanki S, Kerk SA, Chen B, Castillo C, Hsu PP, Do BT, Singhal R, Dame MK, Lee HJ, Spence JR, Lakhal-Littleton S, Vander Heiden MG, Lyssiotis CA, Xue X, Shah YM
Nature metabolism 2021 Jul;3(7):969-982

---

TCDD induced lipid accumulation by impairment of autophagic flux in THP-1 macrophages.

Lu J, Liu M, Fan Y, Zheng H, Guan S
Environmental science and pollution research international 2021 Jul;28(27):36053-36059

---

NT5DC2 promotes leiomyosarcoma tumour cell growth via stabilizing unpalmitoylated TEAD4 and generating a positive feedback loop.

Hu B, Zhou S, Hu X, Zhang H, Lan X, Li M, Wang Y, Hu Q
Journal of cellular and molecular medicine 2021 Jul;25(13):5976-5987

---

Comparison of multi-walled carbon nanotubes and halloysite nanotubes on lipid profiles in human umbilical vein endothelial cells.

Liu Y, Hu Q, Huang C, Cao Y
NanoImpact 2021 Jul;23:100333

---

TLR2 senses the SARS-CoV-2 envelope protein to produce inflammatory cytokines.

Zheng M, Karki R, Williams EP, Yang D, Fitzpatrick E, Vogel P, Jonsson CB, Kanneganti TD
Nature immunology 2021 Jul;22(7):829-838

---

Effect of the interference with DRP1 expression on the biological characteristics of glioma stem cells.

Zhang L, Cao H, Tao H, Yang J, Gong W, Hu Q
Experimental and therapeutic medicine 2021 Jul;22(1):696

---

A  conserved ubiquitin- and ESCRT-dependent pathway internalizes human lysosomal membrane proteins for degradation.

Zhang W, Yang X, Chen L, Liu YY, Venkatarangan V, Reist L, Hanson P, Xu H, Wang Y, Li M
PLoS biology 2021 Jul;19(7):e3001361

---

C1orf61 promotes hepatocellular carcinoma metastasis and increases the therapeutic response to sorafenib.

Yu Y, Wang Z, Huang Z, Tang X, Huang X, Li W
Biochimica et biophysica acta. Molecular cell research 2021 Jul;1868(8):119048

---

Visfatin regulates Pg LPS-induced proinflammatory/prodegradative effects in healthy and inflammatory periodontal cells partially via NF-κB pathway.

Yao S, Jiang C, Zhang H, Gao X, Guo Y, Cao Z
Biochimica et biophysica acta. Molecular cell research 2021 Jul;1868(8):119042

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Ets-2 deletion in myeloid cells attenuates IL-1α-mediated inflammatory disease caused by a Ptpn6 point mutation.

Tartey S, Gurung P, Karki R, Burton A, Hertzog P, Kanneganti TD
Cellular & molecular immunology 2021 Jul;18(7):1798-1808

---

Mycobacterium tuberculosis inhibits the NLRP3 inflammasome activation via its phosphokinase PknF.

Rastogi S, Ellinwood S, Augenstreich J, Mayer-Barber KD, Briken V
PLoS pathogens 2021 Jul;17(7):e1009712

---

DENV NS1 and MMP-9 cooperate to induce vascular leakage by altering endothelial cell adhesion and tight junction.

Pan P, Li G, Shen M, Yu Z, Ge W, Lao Z, Fan Y, Chen K, Ding Z, Wang W, Wan P, Shereen MA, Luo Z, Chen X, Zhang Q, Lin L, Wu J
PLoS pathogens 2021 Jul;17(7):e1008603

---

Chemical conjugation of FITC to track silica nanoparticles in vivo and in vitro: An emerging method to assess the reproductive toxicity of industrial nanomaterials.

Li J, Tian J, Yin H, Peng Y, Liu S, Yao S, Zhang L
Environment international 2021 Jul;152:106497

---

Andrographolide Attenuates Gut-Brain-Axis Associated Pathology in Gulf War Illness by Modulating Bacteriome-Virome Associated Inflammation and Microglia-Neuron Proinflammatory Crosstalk.

Saha P, Skidmore PT, Holland LA, Mondal A, Bose D, Seth RK, Sullivan K, Janulewicz PA, Horner R, Klimas N, Nagarkatti M, Nagarkatti P, Lim ES, Chatterjee S
Brain sciences 2021 Jul 9;11(7)

---

ets1 associates with KMT5A to participate in high glucose-mediated EndMT via upregulation of PFN2 expression in diabetic nephropathy.

Lu L, Zhong Z, Gu J, Nan K, Zhu M, Miao C
Molecular medicine (Cambridge, Mass.) 2021 Jul 8;27(1):74

---

Inhibition of xCT suppresses the efficacy of anti-PD-1/L1 melanoma treatment through exosomal PD-L1-induced macrophage M2 polarization.

Liu N, Zhang J, Yin M, Liu H, Zhang X, Li J, Yan B, Guo Y, Zhou J, Tao J, Hu S, Chen X, Peng C
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Jul 7;29(7):2321-2334

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Baicalein Delays H(2)O(2)-Induced Astrocytic Senescence through Inhibition of Senescence-Associated Secretory Phenotype (SASP), Suppression of JAK2/STAT1/NF-κB Pathway, and Regulation of Leucine Metabolism.

Gao L, Zheng WG, Wu XK, Du GH, Qin XM
ACS chemical neuroscience 2021 Jul 7;12(13):2320-2335

---

Piperlongumine inhibits migration and proliferation of castration-resistant prostate cancer cells via triggering persistent DNA damage.

Zhang DF, Yang ZC, Chen JQ, Jin XX, Qiu YD, Chen XJ, Shi HY, Liu ZG, Wang MS, Liang G, Zheng XH
BMC complementary medicine and therapies 2021 Jul 6;21(1):195

---

Baicalein inhibits RLS3-induced ferroptosis in melanocytes.

Yang M, Li X, Li H, Zhang X, Liu X, Song Y
Biochemical and biophysical research communications 2021 Jul 5;561:65-72

---

Melatonin alleviates Ochratoxin A-induced liver inflammation involved intestinal microbiota homeostasis and microbiota-independent manner.

Xia D, Yang L, Li Y, Chen J, Zhang X, Wang H, Zhai S, Jiang X, Meca G, Wang S, Huang L, Zhu S, Fu Y, Ma W, Zhu Y, Ye H, Wang W
Journal of hazardous materials 2021 Jul 5;413:125239

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mPEG(2k)-PCL(x) Polymeric Micelles Influence Pharmacokinetics and Hypoglycemic Efficacy of Metformin through Inhibition of Organic Cation Transporters in Rats.

Zhang Y, Sun M, Jian S, Huang J, Xiao C, Zhang X, Hu R, Si L
Molecular pharmaceutics 2021 Jul 5;18(7):2586-2599

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The intrinsic role and mechanism of tumor expressed-CD38 on lung adenocarcinoma progression.

Gao L, Liu Y, Du X, Ma S, Ge M, Tang H, Han C, Zhao X, Liu Y, Shao Y, Wu Z, Zhang L, Meng F, Xiao-Feng Qin F
Cell death & disease 2021 Jul 5;12(7):680

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Probiotic-fermented black tartary buckwheat alleviates hyperlipidemia and gut microbiota dysbiosis in rats fed with a high-fat diet.

Ren Y, Wu S, Xia Y, Huang J, Ye J, Xuan Z, Li P, Du B
Food & function 2021 Jul 5;12(13):6045-6057

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L-Theanine regulates glutamine metabolism and immune function by binding to cannabinoid receptor 1.

Liu A, Lin L, Xu W, Gong Z, Liu Z, Xiao W
Food & function 2021 Jul 5;12(13):5755-5769

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NR1D1 suppressed the growth of ovarian cancer by abrogating the JAK/STAT3 signaling pathway.

Wang H, Fu Y
BMC cancer 2021 Jul 30;21(1):871

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Anti-anemia drug FG4592 retards the AKI-to-CKD transition by improving vascular regeneration and antioxidative capability.

Wu M, Chen W, Miao M, Jin Q, Zhang S, Bai M, Fan J, Zhang Y, Zhang A, Jia Z, Huang S
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1707-1726

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Glycoursodeoxycholic acid ameliorates diet-induced metabolic disorders with inhibiting endoplasmic reticulum stress.

Cheng L, Chen T, Guo M, Liu P, Qiao X, Wei Y, She J, Li B, Xi W, Zhou J, Yuan Z, Wu Y, Liu J
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1689-1706

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Subregion-Specific Regulation of Dopamine D1 Receptor Signaling in the Striatum: Implication for L-DOPA-Induced Dyskinesia.

Sugiyama K, Kuroiwa M, Shuto T, Ohnishi YN, Kawahara Y, Miyamoto Y, Fukuda T, Nishi A
The Journal of neuroscience : the official journal of the Society for Neuroscience 2021 Jul 28;41(30):6388-6414

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Growth Hormone Receptor (GHR) 6Ω Pseudoexon Activation: a Novel Cause of Severe Growth Hormone Insensitivity.

Cottrell E, Maharaj A, Williams J, Chatterjee S, Cirillo G, Miraglia Del Giudice E, Festa A, Palumbo S, Capalbo D, Salerno M, Pignata C, Savage MO, Schilbach K, Bidlingmaier M, Hwa V, Metherell LA, Grandone A, Storr HL
The Journal of clinical endocrinology and metabolism 2021 Jul 28;

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HELLS serves as a poor prognostic biomarker and its downregulation reserves the malignant phenotype in pancreatic cancer.

Wang FJ, Jing YH, Cheng CS, Cao ZQ, Jiao JY, Chen Z
BMC medical genomics 2021 Jul 27;14(1):189

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Serum exosomes from young rats improve the reduced osteogenic differentiation of BMSCs in aged rats with osteoporosis after fatigue loading in vivo.

Xun J, Li C, Liu M, Mei Y, Zhou Q, Wu B, Xie F, Liu Y, Dai R
Stem cell research & therapy 2021 Jul 27;12(1):424

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Effects of Coated Cysteamine on Oxidative Stress and Inflammation in Weaned Pigs.

Wang S, Bai M, Xu K, Shao Y, Yang Z, Xiong X, Huang R, Li Y, Liu H
Animals : an open access journal from MDPI 2021 Jul 27;11(8)

---

Nuclear iASPP determines cell fate by selectively inhibiting either p53 or NF-κB.

Ge W, Wang Y, Zheng S, Zhao D, Wang X, Zhang X, Hu Y
Cell death discovery 2021 Jul 26;7(1):195

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Integrated analysis of m(6)A mRNA methylation in rats with monocrotaline-induced pulmonary arterial hypertension.

Zeng Y, Huang T, Zuo W, Wang D, Xie Y, Wang X, Xiao Z, Chen Z, Liu Q, Liu N, Xiao Y
Aging 2021 Jul 26;13(14):18238-18256

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Effects of Loblolly Pine Biochar and Wood Vinegar on Poultry Litter Nutrients and Microbial Abundance.

Mohammadi-Aragh MK, Stokes CE, Street JT, Linhoss JE
Animals : an open access journal from MDPI 2021 Jul 26;11(8)

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Phenethylamine in chlorella alleviates high-fat diet-induced mouse liver damage by regulating generation of methylglyoxal.

Zheng Y, Martin-Morales A, Wang J, Fujishima M, Okumura E, Sato K
NPJ science of food 2021 Jul 23;5(1):22

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Hypoxic preconditioning rejuvenates mesenchymal stem cells and enhances neuroprotection following intracerebral hemorrhage via the miR-326-mediated autophagy.

Liu J, He J, Ge L, Xiao H, Huang Y, Zeng L, Jiang Z, Lu M, Hu Z
Stem cell research & therapy 2021 Jul 22;12(1):413

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VALD-3, a Schiff base ligand synthesized from o-vanillin derivatives, induces cell cycle arrest and apoptosis in breast cancer cells by inhibiting the Wnt/β-catenin pathway.

Li H, Dang C, Tai X, Xue L, Meng Y, Ma S, Zhang J
Scientific reports 2021 Jul 22;11(1):14985

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Lactate secreted by PKM2 upregulation promotes Galectin-9-mediated immunosuppression via inhibiting NF-κB pathway in HNSCC.

Chang H, Xu Q, Li J, Li M, Zhang Z, Ma H, Yang X
Cell death & disease 2021 Jul 21;12(8):725

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Spodoptera frugiperda mRNA export factor interacts with and mediates the nuclear import of Autographa californica multiple nucleopolyhedrovirus ORF34 (Ac34).

Tang Z, Luo W, Huang Z, Yuan M, Wu W, Yang K
Virus research 2021 Jul 2;299:198438

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Establishment of a specific in vivo Cu(Ⅰ) reporting system based on metallothionein screening.

Ma M, Qiu B, Jin J, Wang J, Nie Y, Liang Y, Yu Z, Teng CB
Metallomics : integrated biometal science 2021 Jul 2;13(7)

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PUM1 represses CDKN1B translation and contributes to prostate cancer progression.

Li X, Yang J, Chen X, Cao D, Xu EY
Journal of biomedical research 2021 Jul 16;35(5):371-382

---

Potential effect of EGCG on the anti-tumor efficacy of metformin in melanoma cells.

Xu A, Lee J, Zhao Y, Wang Y, Li X, Xu P
Journal of Zhejiang University. Science. B 2021 Jul 15;22(7):548-562

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The role of PKA/PP2B-mediated Drp1 phosphorylation and the subsequent EGFR inhibition in Cr(VI)-induced premature senescence.

Li S, Ma Y, Liang Y, Liang N, Ye S, Xiao F
Ecotoxicology and environmental safety 2021 Jul 15;218:112300

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Decreased expression of the clock gene Bmal1 is involved in the pathogenesis of temporal lobe epilepsy.

Wu H, Liu Y, Liu L, Meng Q, Du C, Li K, Dong S, Zhang Y, Li H, Zhang H
Molecular brain 2021 Jul 14;14(1):113

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p53 deficiency induces MTHFD2 transcription to promote cell proliferation and restrain DNA damage.

Li G, Wu J, Li L, Jiang P
Proceedings of the National Academy of Sciences of the United States of America 2021 Jul 13;118(28)

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Cyclophilin A Inhibits Human Respiratory Syncytial Virus (RSV) Replication by Binding to RSV-N through Its PPIase Activity.

Liang W, Zhang Y, Li M, Al-Shaebi F, Li J, Zhang J, Wei L
Journal of virology 2021 Jul 12;95(15):e0056321

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Stimuli-Responsive and Highly Penetrable Nanoparticles as a Multifunctional Nanoplatform for Boosting Nonsmall Cell Lung Cancer siRNA Therapy.

Shi M, Wang Y, Zhao X, Zhang J, Hu H, Qiao M, Zhao X, Chen D
ACS biomaterials science & engineering 2021 Jul 12;7(7):3141-3155

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Activation of Adenosine A(1) Receptor in Ischemic Stroke: Neuroprotection by Tetrahydroxy Stilbene Glycoside as an Agonist.

Ruan L, Li G, Zhao W, Meng H, Zheng Q, Wang J
Antioxidants (Basel, Switzerland) 2021 Jul 12;10(7)

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The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability.

Pan Q, Zhong S, Wang H, Wang X, Li N, Li Y, Zhang G, Yuan H, Lian Y, Chen Q, Han Y, Guo J, Liu Q, Qiu T, Jiang J, Li Q, Tan M, Yin H, Peng J, Xiao Y, Qin J
Molecular cell 2021 Jul 1;81(13):2736-2751.e8

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Evaluating the protective effects of individual or combined ginsenoside compound K and the downregulation of soluble epoxide hydrolase expression against sodium valproate-induced liver cell damage.

Zhou L, Zeng X, Rao T, Tan Z, Zhou G, Ouyang D, Chen L
Toxicology and applied pharmacology 2021 Jul 1;422:115555

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MicroRNA-363-3p promotes apoptosis in response to cadmium-induced renal injury by down-regulating phosphoinositide 3-kinase expression.

Chen J, Lai W, Deng Y, Liu M, Dong M, Liu Z, Wang T, Li X, Zhao Z, Yin X, Yang J, Yu R, Liu L
Toxicology letters 2021 Jul 1;345:12-23

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p55PIK deficiency and its NH(2)-terminal derivative inhibit inflammation and emphysema in COPD mouse model.

Wang T, Du X, Wang Z, Gu Y, Huang Q, Wu J, Zhan Y, Chen J, Xiao C, Xie J
American journal of physiology. Lung cellular and molecular physiology 2021 Jul 1;321(1):L159-L173

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A Pan-Histone Deacetylase Inhibitor Enhances the Antitumor Activity of B7-H3-Specific CAR T Cells in Solid Tumors.

Lei X, Ou Z, Yang Z, Zhong J, Zhu Y, Tian J, Wu J, Deng H, Lin X, Peng Y, Li B, He L, Tu Z, Chen W, Li Q, Liu N, Zhang H, Wang Z, Fang Z, Yamada T, Lv X, Tian T, Pan G, Wu F, Xiao L, Zhang L, Cai T, Wang X, Tannous BA, Li J, Kontos F, Ferrone S, Fan S
Clinical cancer research : an official journal of the American Association for Cancer Research 2021 Jul 1;27(13):3757-3771

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Novel functional variants in the Notch pathway and survival of Chinese colorectal cancer.

Qu X, Zhao L, Wang M, Zhang R, Cheng L, Qiu L, Tong X, Cai S, Wei Q, Li Q
International journal of cancer 2021 Jul 1;149(1):84-96

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Alterations of GABA B receptors in the APP/PS1 mouse model of Alzheimer's disease.

Salazar AM, Leisgang AM, Ortiz AA, Murtishaw AS, Kinney JW
Neurobiology of aging 2021 Jan;97:129-143

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Identification and validation of L Antigen Family Member 3 as an immune-related biomarker associated with the progression of papillary thyroid cancer.

Dong X, Yang Q, Gu J, Lv S, Song D, Chen D, Song J, Zhang X, Huang D
International immunopharmacology 2021 Jan;90:107267

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Postnatal overfeeding induces hepatic microRNA-221 expression and impairs the PI3K/AKT pathway in adult male rats.

Huang F, Zhu P, Wang J, Chen J, Lin W
Pediatric research 2021 Jan;89(1):143-149

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Uncaria rhynchophylla ameliorates unpredictable chronic mild stress-induced depression in mice via activating 5-HT(1A) receptor: Insights from transcriptomics.

Qiao YL, Zhou JJ, Liang JH, Deng XP, Zhang ZJ, Huang HL, Li S, Dai SF, Liu CQ, Luan ZL, Yu ZL, Sun CP, Ma XC
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jan;81:153436

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Regulation of branched-chain amino acid metabolism by hypoxia-inducible factor in glioblastoma.

Zhang B, Chen Y, Shi X, Zhou M, Bao L, Hatanpaa KJ, Patel T, DeBerardinis RJ, Wang Y, Luo W
Cellular and molecular life sciences : CMLS 2021 Jan;78(1):195-206

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miR-937-5p targets SOX17 to modulate breast cancer cell cycle and cell proliferation through the Wnt signaling pathway.

Xiong X, Xu W, Gong J, Wang L, Dai M, Chen G, Yuan L
Cellular signalling 2021 Jan;77:109818

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Isoorientin exerts a urate-lowering effect through inhibition of xanthine oxidase and regulation of the TLR4-NLRP3 inflammasome signaling pathway.

An MF, Wang MY, Shen C, Sun ZR, Zhao YL, Wang XJ, Sheng J
Journal of natural medicines 2021 Jan;75(1):129-141

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Layer-specific strain for assessing the effect of naringin on systolic myocardial dysfunction induced by sepsis and its underlying mechanisms.

Sun LJ, Qiao W, Xiao YJ, Ren WD
The Journal of international medical research 2021 Jan;49(1):300060520986369

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Esomeprazole overcomes paclitaxel-resistance and enhances anticancer effects of paclitaxel by inducing autophagy in A549/Taxol cells.

Bai Z, Ding N, Ge J, Wang Y, Wang L, Wu N, Wei Q, Xu S, Liu X, Zhou G
Cell biology international 2021 Jan;45(1):177-187

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Topotecan induces hepatocellular injury via ASCT2 mediated oxidative stress.

Zhou G, Qin M, Zhang X, Yang J, Yu H
Gastroenterologia y hepatologia 2021 Jan;44(1):1-12

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Small extracellular vesicles containing miR-30a-3p attenuate the migration and invasion of hepatocellular carcinoma by targeting SNAP23 gene.

Liu C, Zhou X, Long Q, Zeng H, Sun Q, Chen Y, Wu D, Liu L
Oncogene 2021 Jan;40(2):233-245

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FBW7-NRA41-SCD1 axis synchronously regulates apoptosis and ferroptosis in pancreatic cancer cells.

Ye Z, Zhuo Q, Hu Q, Xu X, Mengqi Liu, Zhang Z, Xu W, Liu W, Fan G, Qin Y, Yu X, Ji S
Redox biology 2021 Jan;38:101807

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Senolytic therapy ameliorates renal fibrosis postacute kidney injury by alleviating renal senescence.

Li C, Shen Y, Huang L, Liu C, Wang J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21229

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Neuropathy-associated histidyl-tRNA synthetase variants attenuate protein synthesis in vitro and disrupt axon outgrowth in developing zebrafish.

Mullen P, Abbott JA, Wellman T, Aktar M, Fjeld C, Demeler B, Ebert AM, Francklyn CS
The FEBS journal 2021 Jan;288(1):142-159

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Arsenic exposure increased expression of HOTAIR and LincRNA-p21 in vivo and vitro.

Tan J, Sun M, Luo Q, Sun H, Wang M, Jiang C, Li S, He Y
Environmental science and pollution research international 2021 Jan;28(1):587-596

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CircRNA-vgll3 promotes osteogenic differentiation of adipose-derived mesenchymal stem cells via modulating miRNA-dependent integrin α5 expression.

Zhang D, Ni N, Wang Y, Tang Z, Gao H, Ju Y, Sun N, He X, Gu P, Fan X
Cell death and differentiation 2021 Jan;28(1):283-302

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SNHG1 represses the anti-cancer roles of baicalein in cervical cancer through regulating miR-3127-5p/FZD4/Wnt/β-catenin signaling.

Yu X, Xia J, Cao Y, Tang L, Tang X, Li Z
Experimental biology and medicine (Maywood, N.J.) 2021 Jan;246(1):20-30

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Endogenous promoter-driven sgRNA for monitoring the expression of low-abundance transcripts and lncRNAs.

Gao N, Hu J, He B, Ji Z, Hu X, Huang J, Wei Y, Peng J, Wei Y, Zhou Y, Shen X, Li H, Feng X, Xiao Q, Shi L, Sun Y, Zhou C, Zhou H, Yang H
Nature cell biology 2021 Jan;23(1):99-108

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Protection against Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice by Neferine, A Natural Product from Nelumbo nucifera Gaertn.

Min X, Guo Y, Zhou Y, Chen X
Cell journal 2021 Jan;22(4):523-531

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Quantitative proteomics reveals stage-specific protein regulation of triple negative breast cancer.

Lin Y, Lin L, Fu F, Wang C, Hu A, Xie J, Jiang M, Wang Z, Yang L, Guo R, Yang P, Shen H
Breast cancer research and treatment 2021 Jan;185(1):39-52

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Loss of WD2 subdomain of Apaf-1 forms an apoptosome structure which blocks activation of caspase-3 and caspase-9.

Noori AR, Tashakor A, Nikkhah M, Eriksson LA, Hosseinkhani S, Fearnhead HO
Biochimie 2021 Jan;180:23-29

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Characteristics of inflammation process in monocrotaline-induced pulmonary arterial hypertension in rats.

Tang C, Luo Y, Li S, Huang B, Xu S, Li L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jan;133:111081

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Neuroprotective effects of kukoamine A on 6-OHDA-induced Parkinson's model through apoptosis and iron accumulation inhibition.

Li X, Jiang XW, Chu HX, Zhao QC, Ding HW, Cai CH
Chinese herbal medicines 2021 Jan;13(1):105-115

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Improved BMP2-CPC-stimulated osteogenesis in vitro and in vivo via modulation of macrophage polarization.

Shen H, Shi J, Zhi Y, Yang X, Yuan Y, Si J, Shen SGF
Materials science & engineering. C, Materials for biological applications 2021 Jan;118:111471

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Hyperglycemia-reduced NAD(+) biosynthesis impairs corneal epithelial wound healing in diabetic mice.

Li Y, Li J, Zhao C, Yang L, Qi X, Wang X, Zhou Q, Shi W
Metabolism: clinical and experimental 2021 Jan;114:154402

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MiR-362 suppresses cervical cancer progression via directly targeting BAP31 and activating TGFβ/Smad pathway.

Yang S, Sun Y, Jiang D, Wang J, Dang E, Li Z, Zhou J, Lu Y, Shi J, Tao L, Wang J, Jin B, Zheng L, Yang K
Cancer medicine 2021 Jan;10(1):305-316

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Identification of an N6-methyladenosine-mediated positive feedback loop that promotes Epstein-Barr virus infection.

Dai DL, Li X, Wang L, Xie C, Jin Y, Zeng MS, Zuo Z, Xia TL
The Journal of biological chemistry 2021 Jan-Jun;296:100547

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Androgen receptor splicing variant 7 (ARV7) inhibits docetaxel sensitivity by inactivating the spindle assembly checkpoint.

Yu B, Liu Y, Luo H, Fu J, Li Y, Shao C
The Journal of biological chemistry 2021 Jan-Jun;296:100276

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The ATPase ATP6V1A facilitates rabies virus replication by promoting virion uncoating and interacting with the viral matrix protein.

Liu X, Li F, Zhang J, Wang L, Wang J, Wen Z, Wang Z, Shuai L, Wang X, Ge J, Zhao D, Bu Z
The Journal of biological chemistry 2021 Jan-Jun;296:100096

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Protective Effect of Retrograde Reperfusion Against Hepatic Autophagy Impairment in Rat Liver Transplantation.

Cheng Y, Lan H, Chen Y, Jiang Y, Chen Y
Transplantation proceedings 2021 Jan-Feb;53(1):443-449

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Overexpression of ICAT Inhibits the Progression of Colorectal Cancer by Binding with β-Catenin in the Cytoplasm.

Hu J, Wang Z, Chen J, Yu Z, Zhang J, Li W, Lin M, Yang X, Liu H
Technology in cancer research & treatment 2021 Jan-Dec;20:15330338211041253

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The EGFR-HSF1 axis accelerates the tumorigenesis of pancreatic cancer.

Qian W, Chen K, Qin T, Xiao Y, Li J, Yue Y, Zhou C, Ma J, Duan W, Lei J, Han L, Li L, Shen X, Wu Z, Ma Q, Wang Z
Journal of experimental & clinical cancer research : CR 2021 Jan 9;40(1):25

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Identification of the atypical cadherin FAT1 as a novel glypican-3 interacting protein in liver cancer cells.

Meng P, Zhang YF, Zhang W, Chen X, Xu T, Hu S, Liang X, Feng M, Yang X, Ho M
Scientific reports 2021 Jan 8;11(1):40

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Cell surface GRP78 regulates BACE2 via lysosome-dependent manner to maintain mesenchymal phenotype of glioma stem cells.

Chen Z, Wang H, Zhang Z, Xu J, Qi Y, Xue H, Gao Z, Zhao R, Wang S, Zhang S, Qiu W, Guo X, Li G
Journal of experimental & clinical cancer research : CR 2021 Jan 7;40(1):20

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Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes.

Karki R, Sharma BR, Tuladhar S, Williams EP, Zalduondo L, Samir P, Zheng M, Sundaram B, Banoth B, Malireddi RKS, Schreiner P, Neale G, Vogel P, Webby R, Jonsson CB, Kanneganti TD
Cell 2021 Jan 7;184(1):149-168.e17

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β-Conglycinin induces the formation of neutrophil extracellular traps dependent on NADPH oxidase-derived ROS, PAD4, ERK1/2 and p38 signaling pathways in mice.

Liu X, Fu Y, Wang J, Wu D, Li S, Wang C, Yang Z, Zhou E
Food & function 2021 Jan 7;12(1):154-161

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Yangonin inhibits ethanol-induced hepatocyte senescence via miR-194/FXR axis.

Dong R, Wang X, Wang L, Wang C, Huang K, Fu T, Liu K, Wu J, Sun H, Meng Q
European journal of pharmacology 2021 Jan 5;890:173653

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Progranulin induces immune escape in breast cancer via up-regulating PD-L1 expression on tumor-associated macrophages (TAMs) and promoting CD8(+) T cell exclusion.

Fang W, Zhou T, Shi H, Yao M, Zhang D, Qian H, Zeng Q, Wang Y, Jin F, Chai C, Chen T
Journal of experimental & clinical cancer research : CR 2021 Jan 4;40(1):4

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NEO100 enables brain delivery of blood‒brain barrier impermeable therapeutics.

Wang W, Marín-Ramos NI, He H, Zeng S, Cho HY, Swenson SD, Zheng L, Epstein AL, Schönthal AH, Hofman FM, Chen L, Chen TC
Neuro-oncology 2021 Jan 30;23(1):63-75

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Effect of Pregnane X Receptor on CYP3A29 Expression in Porcine Alveolar Macrophages during Mycoplasma hyopneumoniae Infection.

Yang X, Xing F, Wang L, Zhao W, Fu Y, Tu F, Li B, Fang X, Ren S
Animals : an open access journal from MDPI 2021 Jan 30;11(2)

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Effects of different concentrations of coated nano zinc oxide material on fecal bacterial composition and intestinal barrier in weaned piglets.

Liu H, Bai M, Xu K, Zhou J, Zhang X, Yu R, Huang R, Yin Y
Journal of the science of food and agriculture 2021 Jan 30;101(2):735-745

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ADAM15 Participates in Tick-Borne Encephalitis Virus Replication.

Yang Q, Pei R, Wang Y, Zhou Y, Yang M, Chen X, Chen J
Journal of virology 2021 Jan 28;95(4)

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Angiogenesis is promoted by exosomal DPP4 derived from 5-fluorouracil-resistant colon cancer cells.

Zheng X, Liu J, Li X, Tian R, Shang K, Dong X, Cao B
Cancer letters 2021 Jan 28;497:190-201

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Absolute configuration of tetrandrine and isotetrandrine influences their anti-proliferation effects in human T cells via different regulation of NF-κB.

Xu W, Kusano J, Chen S, Yamamoto R, Matsuda H, Hara Y, Fujii Y, Hayashi S, Tanaka S, Sugiyama K, Yamada H, Hirano T
Zeitschrift fur Naturforschung. C, Journal of biosciences 2021 Jan 27;76(1-2):21-25

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Poly(lactide-co-glycolide) Nanoparticles Mediate Sustained Gene Silencing and Improved Biocompatibility of siRNA Delivery Systems in Mouse Lungs after Pulmonary Administration.

Wu L, Wu LP, Wu J, Sun J, He Z, Rodríguez-Rodríguez C, Saatchi K, Dailey LA, Häfeli UO, Cun D, Yang M
ACS applied materials & interfaces 2021 Jan 27;13(3):3722-3737

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MicroRNA-193a-5p Regulates the Synthesis of Polyunsaturated Fatty Acids by Targeting Fatty Acid Desaturase 1 (FADS1) in Bovine Mammary Epithelial Cells.

Fan Y, Arbab AAI, Zhang H, Yang Y, Lu X, Han Z, Yang Z
Biomolecules 2021 Jan 25;11(2)

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Circular RNA circRUNX1 promotes papillary thyroid cancer progression and metastasis by sponging MiR-296-3p and regulating DDHD2 expression.

Chu J, Tao L, Yao T, Chen Z, Lu X, Gao L, Fang L, Chen J, He G, Shen S, Zhang D
Cell death & disease 2021 Jan 21;12(1):112

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Diosmetin Ameliorates Nonalcoholic Steatohepatitis through Modulating Lipogenesis and Inflammatory Response in a STAT1/CXCL10-Dependent Manner.

Luo N, Yang C, Zhu Y, Chen Q, Zhang B
Journal of agricultural and food chemistry 2021 Jan 20;69(2):655-667

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Perampanel Stimulates Mitochondrial Biogenesis in Neuronal Cells through Activation of the SIRT1/PGC-1α Signaling Pathway.

Jiang Y, Li D, Du Z, Li J, Lu R, Zhou Q, Wang Q, Zhu H
ACS chemical neuroscience 2021 Jan 20;12(2):323-329

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Downregulation of metabotropic glutamate receptor 5 alleviates central sensitization by activating autophagy via inhibiting mTOR pathway in a rat model of chronic migraine.

Niu Y, Zeng X, Qin G, Zhang D, Zhou J, Chen L
Neuroscience letters 2021 Jan 19;743:135552

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Mutations in GDAP1 Influence Structure and Function of the Trans-Golgi Network.

Binięda K, Rzepnikowska W, Kolakowski D, Kaminska J, Szczepankiewicz AA, Nieznańska H, Kochański A, Kabzińska D
International journal of molecular sciences 2021 Jan 18;22(2)

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Synergism of HPV and MNNG repress miR-218 promoting Het-1A cell malignant transformation by targeting GAB2.

Zhang Y, Zheng Y, Pan E, Zhao C, Zhang H, Liu R, Wang S, Pu Y, Yin L
Toxicology 2021 Jan 15;447:152635

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Hypoxic conditioned promotes the proliferation of human olfactory mucosa mesenchymal stem cells and relevant lncRNA and mRNA analysis.

He J, Huang Y, Liu J, Ge L, Tang X, Lu M, Hu Z
Life sciences 2021 Jan 15;265:118861

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Microcystin-leucine arginine induced the apoptosis of GnRH neurons by activating the endoplasmic reticulum stress resulting in a decrease of serum testosterone level in mice.

Jin H, Hou J, Meng X, Ma T, Wang B, Liu Z, Sha X, Ding J, Han X
Ecotoxicology and environmental safety 2021 Jan 15;208:111748

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Zinc offers splenic protection through suppressing PERK/IRE1-driven apoptosis pathway in common carp (Cyprinus carpio) under arsenic stress.

Wang Y, Zhao H, Mu M, Guo M, Xing M
Ecotoxicology and environmental safety 2021 Jan 15;208:111473

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Curcumin ameliorates mercuric chloride-induced liver injury via modulating cytochrome P450 signaling and Nrf2/HO-1 pathway.

Li S, Wang X, Xiao Y, Wang Y, Wan Y, Li X, Li Q, Tang X, Cai D, Ran B, Wu C
Ecotoxicology and environmental safety 2021 Jan 15;208:111426

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Upregulation of silent information regulator 1 alleviates mitochondrial dysfunction in the trigeminal nucleus caudalis in a rat model of chronic migraine.

Liang J, Zhou X, Wang J, Fei ZY, Qin GC, Zhang DK, Zhou JY, Chen LX
Neuroreport 2021 Jan 13;32(2):144-156

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iASPP protects the heart from ischemia injury by inhibiting p53 expression and cardiomyocyte apoptosis.

Yagudin T, Zhao Y, Gao H, Zhang Y, Yang Y, Zhang X, Ma W, Daba TM, Ishmetov V, Kang K, Yang B, Pan Z
Acta biochimica et biophysica Sinica 2021 Jan 12;53(1):102-111

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Salvia miltiorrhiza stems and leaves total phenolic acids combination with tanshinone protect against DSS-induced ulcerative colitis through inhibiting TLR4/PI3K/AKT/mTOR signaling pathway in mice.

Peng KY, Gu JF, Su SL, Zhu Y, Guo JM, Qian DW, Duan JA
Journal of ethnopharmacology 2021 Jan 10;264:113052

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Dysregulation of USP18/FTO/PYCR1 signaling network promotes bladder cancer development and progression.

Song W, Yang K, Luo J, Gao Z, Gao Y
Aging 2021 Jan 10;13(3):3909-3925

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Aptamer-based CRISPR/Cas12a assay for the ultrasensitive detection of extracellular vesicle proteins.

Li H, Xing S, Xu J, He Y, Lai Y, Wang Y, Zhang G, Guo S, Deng M, Zeng M, Liu W
Talanta 2021 Jan 1;221:121670

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An identified PfHMGB1 promotes microcystin-LR-induced liver injury of yellow catfish (Pelteobagrus fulvidraco).

Wang Y, Xiao X, Wang F, Yang Z, Yue J, Shi J, Ke F, Xie Z, Fan Y
Ecotoxicology and environmental safety 2021 Jan 1;207:111266

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The impact of SAMHD1 expression and mutation status in mantle cell lymphoma: An analysis of the MCL Younger and Elderly trial.

Roider T, Wang X, Hüttl K, Müller-Tidow C, Klapper W, Rosenwald A, Stewart JP, de Castro DG, Dreger P, Hermine O, Kluin-Nelemans HC, Grabe N, Dreyling M, Pott C, Ott G, Hoster E, Dietrich S
International journal of cancer 2021 Jan 1;148(1):150-160

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Role of Slit2 upregulation in recurrent miscarriage through regulation of stromal decidualization.

Chen J, Liu J, Gao S, Qiu Y, Wang Y, Zhang Y, Gao L, Qi G, Wu Y, Lash GE, Li P
Placenta 2021 Jan 1;103:1-9

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mTORC1-mediated amino acid signaling is critical for cell fate determination under transplant-induced stress.

Cheng X, Ge M, Zhu S, Li D, Wang R, Xu Q, Chen Z, Xie S, Liu H
FEBS letters 2021 Feb;595(4):462-475

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Mutation analysis of MFSD8 in an amyotrophic lateral sclerosis cohort from mainland China.

Huang L, Liu Z, Yuan Y, Shen L, Jiang H, Tang B, Wang J, Lei L
The European journal of neuroscience 2021 Feb;53(4):1197-1206

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lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.

Dai W, Wang M, Wang P, Wen J, Wang J, Cha S, Xiao X, He Y, Shu R, Bai D
International journal of molecular medicine 2021 Feb;47(2):607-620

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The miR-145-5p/CD36 pathway mediates PCB2-induced apoptosis in MCF-7 cells.

Yuan Y, Xue C, Wu Q, Wang M, Liu J, Zhang L, Xing Q, Liang J, Wu H, Chen Z
Genes & genomics 2021 Feb;43(2):161-171

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Hypoxia-induced PLOD1 overexpression contributes to the malignant phenotype of glioblastoma via NF-κB signaling.

Wang Z, Shi Y, Ying C, Jiang Y, Hu J
Oncogene 2021 Feb;40(8):1458-1475

---

Activation of the G Protein-Coupled Estrogen Receptor Prevented the Development of Acute Colitis by Protecting the Crypt Cell.

Wang Q, Li Z, Liu K, Liu J, Chai S, Chen G, Wen S, Ming T, Wang J, Ma Y, Zeng H, Liu C, Xue B
The Journal of pharmacology and experimental therapeutics 2021 Feb;376(2):281-293

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TAR DNA-Binding Protein 43 is Cleaved by the Protease 3C of Enterovirus A71.

Wo X, Yuan Y, Xu Y, Chen Y, Wang Y, Zhao S, Lin L, Zhong X, Wang Y, Zhong Z, Zhao W
Virologica Sinica 2021 Feb;36(1):95-103

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Enhancer II-targeted dsRNA decreases GDNF expression via histone H3K9 trimethylation to inhibit glioblastoma progression.

Zhang B, Han X, Gao Q, Liu J, Li S, Zha W, Wang X, Guo X, Gao D
Brain research bulletin 2021 Feb;167:22-32

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Upregulated Nmnat2 causes neuronal death and increases seizure susceptibility in temporal lobe epilepsy.

Wu H, Meng Q, Zhang Y, Li H, Liu Y, Dong S, Liu B, Zhang H
Brain research bulletin 2021 Feb;167:1-10

---

Piezo2 channel in nodose ganglia neurons is essential in controlling hypertension in a pathway regulated directly by Nedd4-2.

Huo L, Gao Y, Zhang D, Wang S, Han Y, Men H, Yang Z, Qin X, Wang R, Kong D, Bai H, Zhang H, Zhang W, Jia Z
Pharmacological research 2021 Feb;164:105391

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Effect of Babao Dan on angiogenesis of gastric cancer in vitro by regulating VEGFA/VEGFR2 signaling pathway.

Guan JH, Cao ZY, Guan B, Wei LH, Peng J, Chen YQ, Sferra TJ, Sankararaman S, Zhan ZX, Lin JM
Translational cancer research 2021 Feb;10(2):953-965

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Triptolide inhibits epithelial-mesenchymal transition phenotype through the p70S6k/GSK3/β-catenin signaling pathway in taxol-resistant human lung adenocarcinoma.

Tian Y, Li P, Xiao Z, Zhou J, Xue X, Jiang N, Peng C, Wu L, Tian H, Popper H, Poh ME, Marcucci F, Zhang C, Zhao X
Translational lung cancer research 2021 Feb;10(2):1007-1019

---

Tregs facilitate obesity and insulin resistance via a Blimp-1/IL-10 axis.

Beppu LY, Mooli RGR, Qu X, Marrero GJ, Finley CA, Fooks AN, Mullen ZP, Frias AB Jr, Sipula I, Xie B, Helfrich KE, Watkins SC, Poholek AC, Ramakrishnan SK, Jurczak MJ, D'Cruz LM
JCI insight 2021 Feb 8;6(3)

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NOGOB receptor-mediated RAS signaling pathway is a target for suppressing proliferating hemangioma.

Hu W, Liu Z, Salato V, North PE, Bischoff J, Kumar SN, Fang Z, Rajan S, Hussain MM, Miao QR
JCI insight 2021 Feb 8;6(3)

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Fork head box M1 regulates vascular endothelial growth factor-A expression to promote the angiogenesis and tumor cell growth of gallbladder cancer.

Wang RT, Miao RC, Zhang X, Yang GH, Mu YP, Zhang ZY, Qu K, Liu C
World journal of gastroenterology 2021 Feb 28;27(8):692-707

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Hypoxic pancreatic stellate cell-derived exosomal mirnas promote proliferation and invasion of pancreatic cancer through the PTEN/AKT pathway.

Cao W, Zeng Z, He Z, Lei S
Aging 2021 Feb 26;13(5):7120-7132

---

Human drug efflux transporter ABCC5 confers acquired resistance to pemetrexed in breast cancer.

Chen J, Wang Z, Gao S, Wu K, Bai F, Zhang Q, Wang H, Ye Q, Xu F, Sun H, Lu Y, Liu Y
Cancer cell international 2021 Feb 25;21(1):136

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Exosomes in ovarian cancer ascites promote epithelial-mesenchymal transition of ovarian cancer cells by delivery of miR-6780b-5p.

Cai J, Gong L, Li G, Guo J, Yi X, Wang Z
Cell death & disease 2021 Feb 24;12(2):210

---

Correction: Injectable postoperative enzyme-responsive hydrogels for reversing temozolomide resistance and reducing local recurrence after glioma operation.

Zhao Z, Shen J, Zhang L, Wang L, Xu H, Han Y, Jia J, Lu Y, Yu R, Liu H
Biomaterials science 2021 Feb 23;9(4):1466

---

Impaired Intestinal Akkermansia muciniphila and Aryl Hydrocarbon Receptor Ligands Contribute to Nonalcoholic Fatty Liver Disease in Mice.

Shi Z, Lei H, Chen G, Yuan P, Cao Z, Ser HL, Zhu X, Wu F, Liu C, Dong M, Song Y, Guo Y, Chen C, Hu K, Zhu Y, Zeng XA, Zhou J, Lu Y, Patterson AD, Zhang L
mSystems 2021 Feb 23;6(1)

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Comparison of content-toxicity-activity of six ingenane-type diterpenoids between Euphorbia kansui before and after stir-fried with vinegar by using UFLC-MS/MS, zebrafish embryos and HT-29 cells.

Zhou SK, Zhang Y, Ju YH, Zhang Q, Luo D, Cao YD, Yao WF, Tang YP, Zhang L
Journal of pharmaceutical and biomedical analysis 2021 Feb 20;195:113828

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Small extracellular vesicle-mediated Hsp70 intercellular delivery enhances breast cancer adriamycin resistance.

Hu W, Xu Z, Zhu S, Sun W, Wang X, Tan C, Zhang Y, Zhang G, Xu Y, Tang J
Free radical biology & medicine 2021 Feb 20;164:85-95

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Differential mitochondrial proteomic analysis of A549 cells infected with avian influenza virus subtypes H5 and H9.

Yang Y, Zhang Y, Yang C, Fang F, Wang Y, Chang H, Chen Z, Chen P
Virology journal 2021 Feb 18;18(1):39

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Polyamine Analog Diethylnorspermidine Restricts Coxsackievirus B3 and Is Overcome by 2A Protease Mutation In Vitro.

Hulsebosch BM, Mounce BC
Viruses 2021 Feb 16;13(2)

---

Down-regulation of A(3)AR signaling by IL-6-induced GRK2 activation contributes to Th17 cell differentiation.

Hu S, Guo P, Wang Z, Zhou Z, Wang R, Zhang M, Tao J, Tai Y, Zhou W, Wei W, Wang Q
Experimental cell research 2021 Feb 15;399(2):112482

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Circ_0119872 promotes uveal melanoma development by regulating the miR-622/G3BP1 axis and downstream signalling pathways.

Liu S, Chen L, Chen H, Xu K, Peng X, Zhang M
Journal of experimental & clinical cancer research : CR 2021 Feb 12;40(1):66

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The long noncoding RNA KTN1-AS1 promotes bladder cancer tumorigenesis via KTN1 cis-activation and the consequent initiation of Rho GTPase-mediated signaling.

Hu X, Xiang L, He D, Zhu R, Fang J, Wang Z, Cao K
Clinical science (London, England : 1979) 2021 Feb 12;135(3):555-574

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Protective role of serpina3c as a novel thrombin inhibitor against atherosclerosis in mice.

Qian LL, Ji JJ, Guo JQ, Wu YP, Ma GS, Yao YY
Clinical science (London, England : 1979) 2021 Feb 12;135(3):447-463

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QiShenYiQi pill activates autophagy to attenuate reactive myocardial fibrosis via the PI3K/AKT/mTOR pathway.

Lv S, Yuan P, Lu C, Dong J, Li M, Qu F, Zhu Y, Zhang J
Aging 2021 Feb 11;13(4):5525-5538

---

Diosgenin alleviates hypercholesterolemia via SRB1/CES-1/CYP7A1/FXR pathway in high-fat diet-fed rats.

Yu L, Lu H, Yang X, Li R, Shi J, Yu Y, Ma C, Sun F, Zhang S, Zhang F
Toxicology and applied pharmacology 2021 Feb 1;412:115388

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A novel tonicity-responsive microRNA miR-23a-5p modulates renal cell survival under osmotic stress through targeting heat shock protein 70 HSPA1B.

Kang K, Liao X, Li Q, Chen J, Niu Y, Zeng Y, Xia S, Zeng L, Liu S, Gou D
American journal of physiology. Cell physiology 2021 Feb 1;320(2):C225-C239

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NF-κB pathway play a role in SCD1 deficiency-induced ceramide de novo synthesis.

Zheng RH, Zhang YB, Qiu FN, Liu ZH, Han Y, Huang R, Zhao Y, Yao P, Qiu Y, Ren J
Cancer biology & therapy 2021 Feb 1;22(2):164-174

---

Vascular endothelial cell-secreted exosomes facilitate osteoarthritis pathogenesis by promoting chondrocyte apoptosis.

Yang RZ, Zheng HL, Xu WN, Zheng XF, Li B, Jiang LS, Jiang SD
Aging 2021 Feb 1;13(3):4647-4662

---

Red ginseng has stronger anti-aging effects compared to ginseng possibly due to its regulation of oxidative stress and the gut microbiota.

Peng X, Hao M, Zhao Y, Cai Y, Chen X, Chen H, Zhang Y, Dong L, Liu X, Ding C, Liu W, Yang M, Luo Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Dec;93:153772

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Gastrodin exerts protective effects in reactive TNC1 astrocytes via regulation of the Notch signaling pathway.

Zhang XLN, Yang XK, Wu CY, Yuan Y
Annals of translational medicine 2021 Dec;9(24):1754

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Phosphorylated nuclear factor erythroid 2-related factor 2 promotes the secretion of C-C motif chemokine ligand 2 and the recruitment of M2 macrophages.

Huang Z, Li X, Zhou T, Jiang Y, Shi JH
Annals of translational medicine 2021 Dec;9(23):1719

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IL-27 signalling promotes adipocyte thermogenesis and energy expenditure.

Wang Q, Li D, Cao G, Shi Q, Zhu J, Zhang M, Cheng H, Wen Q, Xu H, Zhu L, Zhang H, Perry RJ, Spadaro O, Yang Y, He S, Chen Y, Wang B, Li G, Liu Z, Yang C, Wu X, Zhou L, Zhou Q, Ju Z, Lu H, Xin Y, Yang X, Wang C, Liu Y, Shulman GI, Dixit VD, Lu L, Yang H, Flavell RA, Yin Z
Nature 2021 Dec;600(7888):314-318

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Hypoxia-inducible factor-1α promotes proliferation of airway smooth muscle cells through miRNA-103-mediated signaling pathway under hypoxia.

Zhang C, Gao J, Zhu S
In vitro cellular & developmental biology. Animal 2021 Dec;57(10):944-952

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SIRT2 tyrosine nitration by peroxynitrite in response to renal ischemia/reperfusion injury.

Wang Y, Wu CJ, Du Y, Liu YQ, Cai JR, Wu XQ, Hu SQ
Free radical research 2021 Dec;55(11-12):1104-1118

---

CoCrMo-Nanoparticles induced peri-implant osteolysis by promoting osteoblast ferroptosis via regulating Nrf2-ARE signalling pathway.

Xu Y, Sang W, Zhong Y, Xue S, Yang M, Wang C, Lu H, Huan R, Mao X, Zhu L, He C, Ma J
Cell proliferation 2021 Dec;54(12):e13142

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Identification of autophagic target RAB13 with small-molecule inhibitor in low-grade glioma via integrated multi-omics approaches coupled with virtual screening of traditional Chinese medicine databases.

Su W, Liao M, Tan H, Chen Y, Zhao R, Jin W, Zhu S, Zhang Y, He L, Liu B
Cell proliferation 2021 Dec;54(12):e13135

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Semaglutide attenuates seizure severity and ameliorates cognitive dysfunction by blocking the NLR family pyrin domain containing 3 inflammasome in pentylenetetrazole‑kindled mice.

Wang L, Ding J, Zhu C, Guo B, Yang W, He W, Li X, Wang Y, Li W, Wang F, Sun T
International journal of molecular medicine 2021 Dec;48(6)

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Endoplasmic reticulum stress pathway mediates T-2 toxin-induced chondrocyte apoptosis.

Liu YN, Mu YD, Wang H, Zhang M, Shi YW, Mi G, Peng LX, Chen JH
Toxicology 2021 Dec;464:152989

---

FOXO1 inhibits prostate cancer cell proliferation via suppressing E2F1 activated NPRL2 expression.

Tang Y, Jiang L, Zhao X, Hu D, Zhao G, Luo S, Du X, Tang W
Cell biology international 2021 Dec;45(12):2510-2520

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3-Hydroxybenzaldehyde and 4-Hydroxybenzaldehyde enhance survival of mouse astrocytes treated with Angiostrongylus cantonensis young adults excretory/secretory products.

Chen KY, Chen YJ, Cheng CJ, Jhan KY, Chiu CH, Wang LC
Biomedical journal 2021 Dec;44(6 Suppl 2):S258-S266

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GLO 1 and PKCλ Regulate ALDH1-positive Breast Cancer Stem Cell Survival.

Motomura H, Tamori S, Yatani MA, Namiki A, Onaga C, Ozaki A, Takasawa R, Mano Y, Sato T, Hara Y, Sato K, Xiong Y, Harada Y, Hanawa T, Tanuma SI, Sasaki K, Ohno S, Akimoto K
Anticancer research 2021 Dec;41(12):5959-5971

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The transcribed ultraconserved element uc.51 promotes the proliferation and metastasis of breast cancer by stabilizing NONO.

Shi X, Huang X, Chen R, Li Y, Xu Y, Zhang W, Zhu Q, Zha X, Wang J
Clinical & experimental metastasis 2021 Dec;38(6):551-571

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ubtor Mutation Causes Motor Hyperactivity by Activating mTOR Signaling in Zebrafish.

Wang T, Zhou M, Zhang Q, Zhang C, Peng G
Neuroscience bulletin 2021 Dec;37(12):1658-1670

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Stigmasterol inhibits the progression of lung cancer by regulating retinoic acid-related orphan receptor C.

Dong Y, Chen C, Chen C, Zhang C, Zhang L, Zhang Y, Li Y, Dong Z
Histology and histopathology 2021 Dec;36(12):1285-1299

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The flavonoid procyanidin C1 has senotherapeutic activity and increases lifespan in mice.

Xu Q, Fu Q, Li Z, Liu H, Wang Y, Lin X, He R, Zhang X, Ju Z, Campisi J, Kirkland JL, Sun Y
Nature metabolism 2021 Dec;3(12):1706-1726

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Caspase-6 promotes activation of the caspase-11-NLRP3 inflammasome during gram-negative bacterial infections.

Zheng M, Karki R, Kancharana B, Berns H, Pruett-Miller SM, Kanneganti TD
The Journal of biological chemistry 2021 Dec;297(6):101379

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MEHP induces pyroptosis and autophagy alternation by cathepsin B activation in INS-1 cells.

Jiang L, Qiu T, Yao X, Chen H, Yao K, Sun X, Yang G, Jiang L, Zhang C, Wang N, Zhang H, Liu X
Environmental science and pollution research international 2021 Dec;28(47):66628-66642

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A bivalent cyclic RGD-siRNA conjugate enhances the antitumor effect of apatinib via co-inhibiting VEGFR2 in non-small cell lung cancer xenografts.

Liao L, Cen B, Li G, Wei Y, Wang Z, Huang W, He S, Yuan Y, Ji A
Drug delivery 2021 Dec;28(1):1432-1442

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Exosomal ANXA2 derived from ovarian cancer cells regulates epithelial-mesenchymal plasticity of human peritoneal mesothelial cells.

Gao L, Nie X, Gou R, Hu Y, Dong H, Li X, Lin B
Journal of cellular and molecular medicine 2021 Dec;25(23):10916-10929

---

FPR2 serves a role in recurrent spontaneous abortion by regulating trophoblast function via the PI3K/AKT signaling pathway.

Li A, Li S, Zhang C, Fang Z, Sun Y, Peng Y, Wang X, Zhang M
Molecular medicine reports 2021 Dec;24(6)

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Knockdown of TRIM9 attenuates irinotecan‑induced intestinal mucositis in IEC‑6 cells by regulating DUSP6 expression via the P38 pathway.

Zhao W, Wang Q
Molecular medicine reports 2021 Dec;24(6)

---

Suppression of ER-stress induction of GRP78 as an anti-neoplastic mechanism of the cardiac glycoside Lanatoside C in pancreatic cancer: Lanatoside C suppresses GRP78 stress induction.

Ha DP, Tsai YL, Lee AS
Neoplasia (New York, N.Y.) 2021 Dec;23(12):1213-1226

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Danshensu derivative ADTM ameliorates CCl(4)‑induced acute liver injury in mice through inhibiting oxidative stress and apoptosis.

Jia S, Chen Q, Wu J, Yao X, Shao J, Cheng X, Zhang C, Cen D, Wang Y, Shen Z, Shan L, Yao X
Pathology, research and practice 2021 Dec;228:153656

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Mel1b and Mel1c melatonin receptors mediate green light-induced secretion of growth hormone in chick adenohypophysis cells via the AC/PKA and ERK1/2 signalling pathways.

Liu X, Wang L, Wang Z, Dong Y, Chen Y, Cao J
Journal of photochemistry and photobiology. B, Biology 2021 Dec;225:112322

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Arsenic (III) induces oxidative stress and inflammation in the gills of common carp, which is ameliorated by zinc (II).

Lu H, Zhao H, Wang Y, Guo M, Mu M, Liu Y, Nie X, Huang P, Xing M
Journal of inorganic biochemistry 2021 Dec;225:111617

---

Knockdown of METTL14 suppresses the malignant progression of non-small cell lung cancer by reducing Twist expression.

Yang F, Yuan WQ, Li J, Luo YQ
Oncology letters 2021 Dec;22(6):847

---

CMPK2 accelerates liver ischemia/reperfusion injury via the NLRP3 signaling pathway.

Luo Y, Zheng D, Mou T, Pu J, Huang Z, Chen W, Zhang Y, Wu Z
Experimental and therapeutic medicine 2021 Dec;22(6):1358

---

Hsa-miR-335 enhances cell migration and invasion in lung adenocarcinoma through targeting Copine-1.

Wang Y, Zhang J, Zhong LY, Huang SJ, Yu NN, Ouyang L, Niu YL, Chen JX, Lu CH, He QY
MedComm 2021 Dec;2(4):810-820

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Antidepressant effect of catalpol on corticosterone-induced depressive-like behavior involves the inhibition of HPA axis hyperactivity, central inflammation and oxidative damage probably via dual regulation of NF-κB and Nrf2.

Song L, Wu X, Wang J, Guan Y, Zhang Y, Gong M, Wang Y, Li B
Brain research bulletin 2021 Dec;177:81-91

---

Small molecule targeting topoisomerase 3β for cancer therapy.

Zhang X, Wang L, Zhang Q, Lyu S, Zhu D, Shen M, Ke X, Qu Y
Pharmacological research 2021 Dec;174:105927

---

Dihydroartemisinin ameliorates retinal vascular dysfunction in diabetes mellitus via the FASN/Kmal-mTOR/SREBP1 feedback loop.

Gu C, She X, Zhou C, Su T, He S, Meng C, Gu Q, Luo D, Zheng Z, Qiu Q
Pharmacological research 2021 Dec;174:105871

---

Viral RNA N6-methyladenosine modification modulates both innate and adaptive immune responses of human respiratory syncytial virus.

Xue M, Zhang Y, Wang H, Kairis EL, Lu M, Ahmad S, Attia Z, Harder O, Zhang Z, Wei J, Chen P, Gao Y, Peeples ME, Sharma A, Boyaka P, He C, Hur S, Niewiesk S, Li J
PLoS pathogens 2021 Dec;17(12):e1010142

---

DNA damage-inducible transcript 3 restrains osteoclast differentiation and function.

Yang B, Sun H, Jia M, He Y, Luo Y, Wang T, Wu Y, Wang J
Bone 2021 Dec;153:116162

---

Acupuncture regulates the autophagy of ovarian granulosa cells in polycystic ovarian syndrome ovulation disorder by inhibiting the PI3K/AKT/mTOR pathway through LncMEG3.

Chen X, Tang H, Liang Y, Wu P, Xie L, Ding Y, Yang P, Long B, Lin J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112288

---

Selenoprotein S attenuates high glucose and/or ox-LDL-induced endothelium injury by regulating Akt/mTOR signaling and autophagy.

Wang Z, Li Y, Yao J, Yu S, Yu H, Men L, Du J
The international journal of biochemistry & cell biology 2021 Dec;141:106111

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Shockwave Treatment Enhanced Extracellular Matrix Production in Articular Chondrocytes Through Activation of the ROS/MAPK/Nrf2 Signaling Pathway.

Shen PC, Chou SH, Lu CC, Huang HT, Chien SH, Huang PJ, Liu ZM, Shih CL, Su SJ, Chen LM, Tien YC
Cartilage 2021 Dec;13(2_suppl):238S-253S

---

Silencing FYVE, RhoGEF, and PH domain containing 1 (FGD1) suppresses melanoma progression by inhibiting PI3K/AKT signaling pathway.

Niu Z, Li Y, Xu Y, Jiang W, Tao R, Chen Y, Han Y
Bioengineered 2021 Dec;12(2):12193-12205

---

Role of Rho guanine nucleotide exchange factors in non-small cell lung cancer.

Zeng RJ, Xie WJ, Zheng CW, Chen WX, Wang SM, Li Z, Cheng CB, Zou HY, Xu LY, Li EM
Bioengineered 2021 Dec;12(2):11169-11187

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Mechanistic insights into the renoprotective role of curcumin in cisplatin-induced acute kidney injury: network pharmacology analysis and experimental validation.

Hui Z, Dong QQ, Shu HP, Tu YC, Liao QQ, Yao LJ
Bioengineered 2021 Dec;12(2):11041-11056

---

Human umbilical vein endothelial cells derived-exosomes promote osteosarcoma cell stemness by activating Notch signaling pathway.

Yang J, Hu Y, Wang L, Sun X, Yu L, Guo W
Bioengineered 2021 Dec;12(2):11007-11017

---

A comprehensive genome-wide analysis of long non-coding RNA and mRNA expression profiles of JAK2V617F-positive classical myeloproliferative neoplasms.

Zhou J, Wu H, Guo C, Li B, Zhou LL, Liang AB, Fu JF
Bioengineered 2021 Dec;12(2):10564-10586

---

Transcription factor 3 (TCF3) combined with histone deacetylase 3 (HDAC3) down-regulates microRNA-101 to promote Burkitt lymphoma cell proliferation and inhibit apoptosis.

Dong L, Huang J, Zu P, Liu J, Gao X, Du J, Li Y
Bioengineered 2021 Dec;12(1):7995-8005

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MicroRNA-26b-5p suppresses the proliferation of tongue squamous cell carcinoma via targeting proline rich 11 (PRR11).

Yi L, Liu Y, Xu A, Li S, Zhang H, Peng M, Li Z, Ren H, Dai J, Luo C, Xiao Y, Zhou X, Long Y
Bioengineered 2021 Dec;12(1):5830-5838

---

Fat mass and obesity-associated protein (FTO) mediates signal transducer and activator of transcription 3 (STAT3)-drived resistance of breast cancer to doxorubicin.

Wang Y, Cheng Z, Xu J, Lai M, Liu L, Zuo M, Dang L
Bioengineered 2021 Dec;12(1):1874-1889

---

MicroRNA miR-188-5p as a mediator of long non-coding RNA MALAT1 regulates cell proliferation and apoptosis in multiple myeloma.

Liu H, Chi Z, Jin H, Yang W
Bioengineered 2021 Dec;12(1):1611-1626

---

A virulent Bacillus cereus strain from deep-sea cold seep induces pyroptosis in a manner that involves NLRP3 inflammasome, JNK pathway, and lysosomal rupture.

Zhao Y, Jiang S, Zhang J, Guan XL, Sun BG, Sun L
Virulence 2021 Dec;12(1):1362-1376

---

ATR kinase activity promotes antibody class switch recombination in B cells through cell cycle regulation without suppressing DSB resection and microhomology usage.

Sun X, Liu M, Bai J, Xu J, Zhu C, Dong J, Chen C
Journal of leukocyte biology 2021 Dec;110(6):1101-1112

---

A living cell-based fluorescent reporter for high-throughput screening of anti-tumor drugs.

Tang N, Li L, Xie F, Lu Y, Zuo Z, Shan H, Zhang Q, Zhang L
Journal of pharmaceutical analysis 2021 Dec;11(6):808-814

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GABA(A) receptor agonist muscimol rescues inhibitory microcircuit defects in the olfactory bulb and improves olfactory function in APP/PS1 transgenic mice.

Hu B, Geng C, Guo F, Liu Y, Zong YC, Hou XY
Neurobiology of aging 2021 Dec;108:47-57

---

1β-Hydroxyalantolactone from Inulae Flos alleviated the progression of pulmonary fibrosis via inhibiting JNK/FOXO1/NF-κB pathway.

Yu B, Jin XQ, Yu WY, Dong YY, Ying HZ, Yu CH
International immunopharmacology 2021 Dec;101(Pt A):108339

---

Dietary hawthorn-leaves flavonoids improves ovarian function and liver lipid metabolism in aged breeder hens.

Dai H, Lv Z, Huang Z, Ye N, Li S, Jiang J, Cheng Y, Shi F
Poultry science 2021 Dec;100(12):101499

---

Mannan-binding lectin deficiency augments hepatic endoplasmic reticulum stress through IP3R-controlled calcium release.

Chen Y, Hu M, Deng F, Wang P, Lin J, Zheng Z, Liu Y, Dong L, Lu X, Chen Z, Zhou J, Zuo D
Cell calcium 2021 Dec;100:102477

---

Transcriptomic-based toxicological investigations of graphene oxide with modest cytotoxicity to human umbilical vein endothelial cells: changes of Toll-like receptor signaling pathways.

Luo Y, Wang X, Cao Y
Toxicology research 2021 Dec;10(6):1104-1115

---

Acquiring high expression of suilysin enable non-epidemic Streptococccus suis to cause streptococcal toxic shock-like syndrome (STSLS) through NLRP3 inflammasome hyperactivation.

Xu L, Lin L, Lu X, Xiao P, Liu R, Wu M, Jin M, Zhang A
Emerging microbes & infections 2021 Dec;10(1):1309-1319

---

The Mechanism of Mitochondrial Injury in Alpha-1 Antitrypsin Deficiency Mediated Liver Disease.

Khodayari N, Wang RL, Oshins R, Lu Y, Millett M, Aranyos AM, Mostofizadeh S, Scindia Y, Flagg TO, Brantly M
International journal of molecular sciences 2021 Dec 9;22(24)

---

SARS-CoV-2 ORF3a Induces Incomplete Autophagy via the Unfolded Protein Response.

Su WQ, Yu XJ, Zhou CM
Viruses 2021 Dec 9;13(12)

---

MiRNA-132/212 regulates tight junction stabilization in blood-brain barrier after stroke.

Yan H, Kanki H, Matsumura S, Kawano T, Nishiyama K, Sugiyama S, Takemori H, Mochizuki H, Sasaki T
Cell death discovery 2021 Dec 8;7(1):380

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NLRP3 inflammasome signal pathway involves in Vibrio harveyi-induced inflammatory response in murine peritoneal macrophages in vitro.

Yu G, Wang J, Zhang W, Yang Q, Liu G, Wang L, Bello BK, Zhang X, Zhang T, Fan H, Zhao P, Liang W, Dong J
Acta biochimica et biophysica Sinica 2021 Dec 8;53(12):1590-1601

---

HOPX Plays a Critical Role in Antiretroviral Drugs Induced Epigenetic Modification and Cardiac Hypertrophy.

Kashyap S, Rabbani M, de Lima I, Kondrachuk O, Patel R, Shafiei MS, Mukker A, Rajakumar A, Gupta MK
Cells 2021 Dec 8;10(12)

---

ZNF382 controls mouse neuropathic pain via silencer-based epigenetic inhibition of Cxcl13 in DRG neurons.

Ma L, Yu L, Jiang BC, Wang J, Guo X, Huang Y, Ren J, Sun N, Gao DS, Ding H, Lu J, Zhou H, Zou L, Gao Y, Wang L, Sun K, Ming Y, Meng Z, Tao YX, Yan M
The Journal of experimental medicine 2021 Dec 6;218(12)

---

Biophysical and biochemical properties of PHGDH revealed by studies on PHGDH inhibitors.

Tan Y, Zhou X, Gong Y, Gou K, Luo Y, Jia D, Dai L, Zhao Y, Sun Q
Cellular and molecular life sciences : CMLS 2021 Dec 31;79(1):27

---

Diacerein attenuates vascular dysfunction by reducing inflammatory response and insulin resistance in type 2 diabetic rats.

He A, Shen J, Xue Y, Xiang Li, Li Y, Huang L, Lv D, Luo M
Biochemical and biophysical research communications 2021 Dec 31;585:68-74

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Irisin Association with Ki-67, MCM3 and MT-I/II in Squamous Cell Carcinomas of the Larynx.

Pinkowska A, Nowinska K, Ciesielska U, Podhorska-Okolow M
Biomolecules 2021 Dec 30;12(1)

---

CD38 activation by monosodium urate crystals contributes to inflammatory responses in human and murine macrophages.

Wen S, Arakawa H, Tamai I
Biochemical and biophysical research communications 2021 Dec 3;581:6-11

---

USP30-AS1 contributes to mitochondrial quality control in glioblastoma cells.

Wang N, Li J, Xin Q, Xu N
Biochemical and biophysical research communications 2021 Dec 3;581:31-37

---

Loss of ATF4 leads to functional aging-like attrition of adult hematopoietic stem cells.

Sun Y, Lin X, Liu B, Zhang Y, Li W, Zhang S, He F, Tian H, Zhu X, Liu X, Wu J, Cai J, Li M
Science advances 2021 Dec 24;7(52):eabj6877

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Antiplatelet and Antithrombotic Effects of Isaridin E Isolated from the Marine-Derived Fungus via Downregulating the PI3K/Akt Signaling Pathway.

Pan N, Li ZC, Li ZH, Chen SH, Jiang MH, Yang HY, Liu YS, Hu R, Zeng YW, Dai LH, Liu L, Wang GL
Marine drugs 2021 Dec 24;20(1)

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Installation of Pargyline, a LSD1 Inhibitor, in the HDAC Inhibitory Template Culminated in the Identification of a Tractable Antiprostate Cancer Agent.

Ojha R, Chen IC, Hsieh CM, Nepali K, Lai RW, Hsu KC, Lin TE, Pan SL, Chen MC, Liou JP
Journal of medicinal chemistry 2021 Dec 23;64(24):17824-17845

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Heat stress affects fetal brain and intestinal function associated with the alterations of placental barrier in late pregnant mouse.

Guo H, Yang Y, Qiao Y, He J, Yao W, Zheng W
Ecotoxicology and environmental safety 2021 Dec 20;227:112916

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Interleukin-37 inhibits inflammation activation and disease severity of PM2.5-induced airway hyperresponsiveness.

Wang M, Hou S, Lu X, Li J, Li R, Yan X
Ecotoxicology and environmental safety 2021 Dec 20;227:112890

---

Cancer-associated fibroblasts promote oral squamous cell carcinoma progression through LOX-mediated matrix stiffness.

Zhang JY, Zhu WW, Wang MY, Zhai RD, Wang Q, Shen WL, Liu LK
Journal of translational medicine 2021 Dec 20;19(1):513

---

Nuclear factor I-C disrupts cellular homeostasis between autophagy and apoptosis via miR-200b-Ambra1 in neural tube defects.

Huang W, Huang T, Liu Y, Fu J, Wei X, Liu D, Ma W, Gu H, Yuan Z
Cell death & disease 2021 Dec 20;13(1):17

---

p66α Suppresses Breast Cancer Cell Growth and Migration by Acting as Co-Activator of p53.

Zhang Q, Zhang Y, Zhang J, Zhang D, Li M, Yan H, Zhang H, Song L, Wang J, Hou Z, Yang Y, Zou X
Cells 2021 Dec 20;10(12)

---

Nucleosomes enter cells by clathrin- and caveolin-dependent endocytosis.

Wang H, Shan X, Ren M, Shang M, Zhou C
Nucleic acids research 2021 Dec 2;49(21):12306-12319

---

Evaluating the Effect of Lenvatinib on Sorafenib-Resistant Hepatocellular Carcinoma Cells.

Shi T, Iwama H, Fujita K, Kobara H, Nishiyama N, Fujihara S, Goda Y, Yoneyama H, Morishita A, Tani J, Yamada M, Nakahara M, Takuma K, Masaki T
International journal of molecular sciences 2021 Dec 2;22(23)

---

A distributed residue network permits conformational binding specificity in a conserved family of actin remodelers.

Hwang T, Parker SS, Hill SM, Ilunga MW, Grant RA, Mouneimne G, Keating AE
eLife 2021 Dec 2;10

---

MIF promotes neurodegeneration and cell death via its nuclease activity following traumatic brain injury.

Ruan Z, Lu Q, Wang JE, Zhou M, Liu S, Zhang H, Durvasula A, Wang Y, Wang Y, Luo W, Wang Y
Cellular and molecular life sciences : CMLS 2021 Dec 18;79(1):39

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d-mannose attenuates lipopolysaccharide-induced osteolysis via CPT1A-Mediated lipid metabolic regulation in macrophages.

Zhang Z, Zhou X, Liu J, Zheng Y, Wu Y, Yang W, Yi Y, Liu J, Wang J
Biochemical and biophysical research communications 2021 Dec 17;583:135-141

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TCF4 and HuR mediated-METTL14 suppresses dissemination of colorectal cancer via N6-methyladenosine-dependent silencing of ARRDC4.

Wang H, Wei W, Zhang ZY, Liu Y, Shi B, Zhong W, Zhang HS, Fang X, Sun CL, Wang JB, Liu LX
Cell death & disease 2021 Dec 17;13(1):3

---

Probiotic Bacillus cereus Alleviates Dextran Sulfate Sodium-Induced Colitis in Mice through Improvement of the Intestinal Barrier Function, Anti-Inflammation, and Gut Microbiota Modulation.

Sheng K, Xu Y, Kong X, Wang J, Zha X, Wang Y
Journal of agricultural and food chemistry 2021 Dec 15;69(49):14810-14823

---

Tangeretin maintains antioxidant activity by reducing CUL3 mediated NRF2 ubiquitination.

Wang Y, Jin R, Chen J, Cao J, Xiao J, Li X, Sun C
Food chemistry 2021 Dec 15;365:130470

---

ERα promotes transcription of tumor suppressor gene ApoA-I by establishing H3K27ac-enriched chromatin microenvironment in breast cancer cells.

Wang B, Shen Y, Liu T, Tan L
Journal of Zhejiang University. Science. B 2021 Dec 15;22(12):1034-1044

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The laminin-binding integrins regulate nuclear factor κB-dependent epithelial cell polarity and inflammation.

Yazlovitskaya EM, Plosa E, Bock F, Viquez OM, Mernaugh G, Gewin LS, De Arcangelis A, Georges-Labouesse E, Sonnenberg A, Blackwell TS, Pozzi A, Zent R
Journal of cell science 2021 Dec 15;134(24)

---

Suppressing Alpha-Hemolysin as Potential Target to Screen of Flavonoids to Combat Bacterial Coinfection.

He S, Deng Q, Liang B, Yu F, Yu X, Guo D, Liu X, Dong H
Molecules (Basel, Switzerland) 2021 Dec 14;26(24)

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TRPV1 channel mediates NLRP3 inflammasome-dependent neuroinflammation in microglia.

Zhang Y, Hou B, Liang P, Lu X, Wu Y, Zhang X, Fan Y, Liu Y, Chen T, Liu W, Peng B, Yin J, Han S, He X
Cell death & disease 2021 Dec 14;12(12):1159

---

α-Synuclein aggregation in the olfactory bulb induces olfactory deficits by perturbing granule cells and granular-mitral synaptic transmission.

Chen F, Liu W, Liu P, Wang Z, Zhou Y, Liu X, Li A
NPJ Parkinson's disease 2021 Dec 13;7(1):114

---

Polysaccharide CM1 from Cordyceps militaris hinders adipocyte differentiation and alleviates hyperlipidemia in LDLR((+/-)) hamsters.

Yu WQ, Yin F, Shen N, Lin P, Xia B, Li YJ, Guo SD
Lipids in health and disease 2021 Dec 13;20(1):178

---

Carnosol alleviates nonalcoholic fatty liver disease by inhibiting mitochondrial dysfunction and apoptosis through targeting of PRDX3.

Geng Y, Wang Y, Sun R, Kang X, Zhao H, Zhu M, Sun Y, Hu Y, Wang Z, Tian X, Zhao Y, Yao J
Toxicology and applied pharmacology 2021 Dec 1;432:115758

---

Involvement of endoplasmic reticulum stress-activated PERK-eIF2α-ATF4 signaling pathway in T-2 toxin-induced apoptosis of porcine renal epithelial cells.

Liu X, Wang Z, Wang X, Yan X, He Q, Liu S, Ye M, Li X, Yuan Z, Wu J, Yi J, Wen L, Li R
Toxicology and applied pharmacology 2021 Dec 1;432:115753

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PAX5-activated lncRNA ARRDC1-AS1 accelerates the autophagy and progression of DLBCL through sponging miR-2355-5p to regulate ATG5.

Xu H, Yu X, Yang Z, Song Q, Cheng S, He Z, Dai L
Life sciences 2021 Dec 1;286:119932

---

Ketamine enhances novel object recognition memory reconsolidation via the BDNF/TrkB pathway in mice.

Fan JF, Tang ZH, Wang SY, Lei S, Zhang B, Tian SW
Physiology & behavior 2021 Dec 1;242:113626

---

Role of the hippo signaling pathway in the extracellular matrix degradation of chondrocytes induced by fluoride exposure.

Yu FF, Zuo J, Fu X, Gao MH, Sun L, Yu SY, Li Z, Zhou GY, Ba Y
Ecotoxicology and environmental safety 2021 Dec 1;225:112796

---

Cypermethrin triggers YY1-mediated testosterone biosynthesis suppression.

Liu C, Qu J, Wu M, Huang X, Li L
Ecotoxicology and environmental safety 2021 Dec 1;225:112792

---

Quercetin reverses chronic unpredictable mild stress-induced depression-like behavior in vivo by involving nuclear factor-E2-related factor 2.

Guan Y, Wang J, Wu X, Song L, Wang Y, Gong M, Li B
Brain research 2021 Dec 1;1772:147661

---

Metformin alleviates hydrogen peroxide-induced inflammation and oxidative stress via inhibiting P2X7R signaling in spinal cord tissue cells neurons.

Wang G, Chen S, Shao Z, Li Y, Wang W, Mao L, Li J, Mei X
Canadian journal of physiology and pharmacology 2021 Aug;99(8):768-774

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AKR1C3 decreased CML sensitivity to Imatinib in bone marrow microenvironment via dysregulation of miR-379-5p.

Pan D, Yang W, Zeng Y, Li W, Wang K, Zhao L, Li J, Ye Y, Guo Q
Cellular signalling 2021 Aug;84:110038

---

Heat shock protein 90 inhibitor ameliorates pancreatic fibrosis by degradation of transforming growth factor-β receptor.

Peng YF, Lin H, Liu DC, Zhu XY, Huang N, Wei YX, Li L
Cellular signalling 2021 Aug;84:110001

---

Microglial Calhm2 regulates neuroinflammation and contributes to Alzheimer's disease pathology.

Cheng J, Dong Y, Ma J, Pan R, Liao Y, Kong X, Li X, Li S, Chen P, Wang L, Yu Y, Yuan Z
Science advances 2021 Aug;7(35)

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Rapid generation of maternal mutants via oocyte transgenic expression of CRISPR-Cas9 and sgRNAs in zebrafish.

Zhang C, Lu T, Zhang Y, Li J, Tarique I, Wen F, Chen A, Wang J, Zhang Z, Zhang Y, Shi DL, Shao M
Science advances 2021 Aug;7(32)

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The intervention of intestinal Wnt/β-catenin pathway alters inflammation and disease severity of CIA.

Tan W, Qiu Y, Chen N, Gao J, Liang J, Liu Y, Zhao D
Immunologic research 2021 Aug;69(4):323-333

---

Milk Polar Lipids Supplementation to Obese Rats During Pregnancy and Lactation Benefited Skeletal Outcomes of Male Offspring.

Han L, Du M, Ren F, Mao X
Molecular nutrition & food research 2021 Aug;65(15):e2001208

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H. pylori infection induces CXCL8 expression and promotes gastric cancer progress through downregulating KLF4.

Liu Z, Wu X, Tian Y, Zhang W, Qiao S, Xu W, Liu Y, Wang S
Molecular carcinogenesis 2021 Aug;60(8):524-537

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Exosomal miR-193b-5p as a regulator of LPS-induced inflammation in dairy cow mammary epithelial cells.

Xu H, Zhang T, Hu X, Xie Y, Wu R, Lian S, Wang J
In vitro cellular & developmental biology. Animal 2021 Aug;57(7):695-703

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Circadian misalignment promotes vascular smooth muscle cell apoptosis via defective autophagy.

Guo Z, Yu B, Li X, Yang X, Wang C, Fan L
Journal of molecular histology 2021 Aug;52(4):799-808

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Progranulin promotes osteogenic differentiation of periodontal membrane stem cells in both inflammatory and non-inflammatory conditions.

Yu M, Sun L, Ba P, Li L, Chen J, Sun Q
The Journal of international medical research 2021 Aug;49(8):3000605211032508

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Lipocalin-2: a role in hepatic gluconeogenesis via AMP-activated protein kinase (AMPK).

Sun WX, Lou K, Chen LJ, Liu SD, Pang SG
Journal of endocrinological investigation 2021 Aug;44(8):1753-1765

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Hepatoprotective effects of loach (Misgurnus anguillicaudatus) lyophilized powder on dimethylnitrosamine-induced liver fibrosis in rats.

Zhang Q, Shang MM, Ling QF, Wu XP, Liu CY
Archives of pharmacal research 2021 Aug;44(8):1-12

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Chicoric acid attenuates hyperglycemia-induced endothelial dysfunction through AMPK-dependent inhibition of oxidative/nitrative stresses.

Ma X, Zhang J, Wu Z, Wang X
Journal of receptor and signal transduction research 2021 Aug;41(4):378-392

---

W436, a novel SMART derivative, exhibits anti-hepatocarcinoma activity by inducing apoptosis and G2/M cell cycle arrest in vitro and in vivo and induces protective autophagy.

Man S, Wu Z, Sun R, Guan Q, Li Z, Zuo D, Zhang W, Wu Y
Journal of biochemical and molecular toxicology 2021 Aug;35(8):e22831

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Immunization with recombinant E(rns)-LTB fusion protein elicits protective immune responses against bovine viral diarrhea virus.

Wang SH, Yang GH, Nie JW, Wang J, Wang YX, Du MZ, Guo L, Yang RJ, Zhu YH
Veterinary microbiology 2021 Aug;259:109084

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Downregulation of SUN2 promotes metastasis of colon cancer by activating BDNF/TrkB signalling by interacting with SIRT1.

Liu L, Li SW, Yuan W, Tang J, Sang Y
The Journal of pathology 2021 Aug;254(5):531-542

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Procyanidin B2 alleviates liver injury caused by cold stimulation through Sonic hedgehog signalling and autophagy.

Ma L, Li C, Lian S, Xu B, Lv H, Liu Y, Lu J, Ji H, Li S, Guo J, Yang H
Journal of cellular and molecular medicine 2021 Aug;25(16):8015-8027

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LncRNA MAYA promotes iron overload and hepatocyte senescence through inhibition of YAP in non-alcoholic fatty liver disease.

Yuan P, Qi X, Song A, Ma M, Zhang X, Lu C, Bian M, Lian N, He J, Zheng S, Jin H
Journal of cellular and molecular medicine 2021 Aug;25(15):7354-7366

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CircPLCE1 facilitates the malignant progression of colorectal cancer by repressing the SRSF2-dependent PLCE1 pre-RNA splicing.

Chen Z, Chen H, Yang L, Li X, Wang Z
Journal of cellular and molecular medicine 2021 Aug;25(15):7244-7256

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Fisetin mitigates hepatic ischemia-reperfusion injury by regulating GSK3β/AMPK/NLRP3 inflammasome pathway.

Pu JL, Huang ZT, Luo YH, Mou T, Li TT, Li ZT, Wei XF, Wu ZJ
Hepatobiliary & pancreatic diseases international : HBPD INT 2021 Aug;20(4):352-360

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DDIT3/CHOP promotes autophagy in chondrocytes via SIRT1-AKT pathway.

Yang C, Xu X, Dong X, Yang B, Dong W, Luo Y, Liu X, Wu Y, Wang J
Biochimica et biophysica acta. Molecular cell research 2021 Aug;1868(9):119074

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Targeting P2RX1 alleviates renal ischemia/reperfusion injury by preserving mitochondrial dynamics.

Zhuang S, Xia S, Huang P, Wu J, Qu J, Chen R, Sun N, Li D, Wu H, Zhang M, Zhang J, Yuan X, Wang X
Pharmacological research 2021 Aug;170:105712

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MondoA-Thioredoxin-Interacting Protein Axis Maintains Regulatory T-Cell Identity and Function in Colorectal Cancer Microenvironment.

Lu Y, Li Y, Liu Q, Tian N, Du P, Zhu F, Han Y, Liu X, Liu X, Peng X, Wang X, Wu Y, Tong L, Li Y, Zhu Y, Wu L, Zhang P, Xu Y, Chen H, Li B, Tong X
Gastroenterology 2021 Aug;161(2):575-591.e16

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Ferroptosis inducer erastin sensitizes NSCLC cells to celastrol through activation of the ROS-mitochondrial fission-mitophagy axis.

Liu M, Fan Y, Li D, Han B, Meng Y, Chen F, Liu T, Song Z, Han Y, Huang L, Chang Y, Cao P, Nakai A, Tan K
Molecular oncology 2021 Aug;15(8):2084-2105

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Momordin Ic induces G0/1 phase arrest and apoptosis in colon cancer cells by suppressing SENP1/c-MYC signaling pathway.

Xianjun F, Xirui X, Jie T, Huiwen M, Shaojun Z, Qiaoyun L, Yunxin L, Xuqun S
Journal of pharmacological sciences 2021 Aug;146(4):249-258

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The active ingredients and mechanisms of Longchai Jiangxue Formula in treating PV, based on UPLC/Q-TOF-MS/MS, systematic pharmacology, and molecular biology validation.

Ming J, Liu W, Wu H, Li Y, Yang E, Wang Z, Xiao H, Quan R, Hu X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Aug;140:111767

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Systematic investigation of the pharmacological mechanism for renal protection by the leaves of Eucommia ulmoides Oliver using UPLC-Q-TOF/MS combined with network pharmacology analysis.

Huang Q, Zhang F, Liu S, Jiang Y, Ouyang D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Aug;140:111735

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Grouper TRAF5 exerts negative regulation on antiviral immune response against iridovirus.

Sun M, Wu S, Zhang X, Zhang L, Kang S, Qin Q, Wei J
Fish & shellfish immunology 2021 Aug;115:7-13

---

CSNK2A1-mediated phosphorylation of HMGA2 modulates cisplatin resistance in cervical cancer.

Shi Z, Wu D, Xu H, Yang J, Sun X
FEBS open bio 2021 Aug;11(8):2245-2255

---

Lipoxin A4 protects primary spinal cord neurons from Erastin-induced ferroptosis by activating the Akt/Nrf2/HO-1 signaling pathway.

Wei N, Lu T, Yang L, Dong Y, Liu X
FEBS open bio 2021 Aug;11(8):2118-2126

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Bone morphogenetic protein-7 inhibits endothelial-to-mesenchymal transition in primary human umbilical vein endothelial cells and mouse model of systemic sclerosis via Akt/mTOR/p70S6K pathway.

Shen C, Jiang Y, Li Q, Liu C, Hu F, Li M
Journal of dermatological science 2021 Aug;103(2):82-92

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Melatonin mediates monochromatic light-induced expression of somatostatin in the hypothalamus and pituitary of chicks.

Qin X, Liu X, Yan X, Long M, Wang Z, Dong Y, Chen Y, Cao J
Poultry science 2021 Aug;100(8):101285

---

Suramin attenuates intervertebral disc degeneration by inhibiting NF-κB signalling pathway.

Liu ZM, Lu CC, Shen PC, Chou SH, Shih CL, Chen JC, Tien YC
Bone & joint research 2021 Aug;10(8):498-513

---

Extract of Cynomorium songaricum ameliorates mitochondrial ultrastructure impairments and dysfunction in two different in vitro models of Alzheimer's disease.

Cheng D, Su L, Wang X, Li X, Li L, Hu M, Lu Y
BMC complementary medicine and therapies 2021 Aug 9;21(1):206

---

Metformin Is a Pyridoxal-5'-phosphate (PLP)-Competitive Inhibitor of SHMT2.

Tramonti A, Cuyàs E, Encinar JA, Pietzke M, Paone A, Verdura S, Arbusà A, Martin-Castillo B, Giardina G, Joven J, Vazquez A, Contestabile R, Cutruzzolà F, Menendez JA
Cancers 2021 Aug 9;13(16)

---

TRIM28 SUMOylates and stabilizes NLRP3 to facilitate inflammasome activation.

Qin Y, Li Q, Liang W, Yan R, Tong L, Jia M, Zhao C, Zhao W
Nature communications 2021 Aug 9;12(1):4794

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Association of CASC18/miR-20a-3p/TGFB2 ceRNA axis with occult lymph node metastasis in tongue squamous cell carcinoma.

Zhou B, Zhou Y, Liu Y, Zhang H, Mao H, Peng M, Xu A, Li Z, Wang H, Tan H, Ren H, Zhou X, Long Y
Molecular medicine (Cambridge, Mass.) 2021 Aug 6;27(1):85

---

DEAD-box helicase 27 enhances stem cell-like properties with poor prognosis in breast cancer.

Li S, Ma J, Zheng A, Song X, Chen S, Jin F
Journal of translational medicine 2021 Aug 6;19(1):334

---

METTL3 regulates PM(2.5)-induced cell injury by targeting OSGIN1 in human airway epithelial cells.

Yuan Q, Zhu H, Liu H, Wang M, Chu H, Zhang Z
Journal of hazardous materials 2021 Aug 5;415:125573

---

Mammalian target of rapamycin signaling pathway is involved in synaptic plasticity of the spinal dorsal horn and neuropathic pain in rats by regulating autophagy.

Hu J, Chen X, Cheng J, Kong F, Xia H, Wu J
Neuroreport 2021 Aug 4;32(11):925-935

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circBTBD7 Promotes Immature Porcine Sertoli Cell Growth through Modulating miR-24-3p/MAPK7 Axis to Inactivate p38 MAPK Signaling Pathway.

Bian Q, Chen B, Weng B, Chu D, Tang X, Yan S, Yin Y, Ran M
International journal of molecular sciences 2021 Aug 30;22(17)

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Targeting Amino Acid Metabolic Reprogramming via L-Type Amino Acid Transporter 1 (LAT1) for Endocrine-Resistant Breast Cancer.

Shindo H, Harada-Shoji N, Ebata A, Sato M, Soga T, Miyashita M, Tada H, Kawai M, Kosaka S, Onuki K, Usami S, Furumoto S, Hayashi S, Abe T, Suzuki T, Ishida T, Sasano H
Cancers 2021 Aug 30;13(17)

---

The COL-4A1 polypeptide destroy endothelial cells through the TGF-β/PI3K/AKT pathway.

Li T, Ling Z, Xie K, Wang Y, Miao Z, Ji X, Li J, Hou W, Tang Q, Yuan X, Li N, Li C, Ding H
Scientific reports 2021 Aug 3;11(1):15761

---

CCT5 interacts with cyclin D1 promoting lung adenocarcinoma cell migration and invasion.

Meng Y, Yang L, Wei X, Luo H, Hu Y, Tao X, He J, Zheng X, Xu Q, Luo K, Yu G, Luo Q
Biochemical and biophysical research communications 2021 Aug 27;567:222-229

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Association of T2285C polymorphism in PARP1 gene coding region with its expression, activity and NSCLC risk along with prognosis.

Wang Y, Xia XB, Tang HZ, Cai JR, Shi XK, Ji HX, Yan XN, Xu T
Mutagenesis 2021 Aug 27;36(4):281-293

---

Glyceraldehyde-3-Phosphate Dehydrogenase Restricted in Cytoplasmic Location by Viral GP5 Facilitates Porcine Reproductive and Respiratory Syndrome Virus Replication via Its Glycolytic Activity.

Liu X, Liu X, Bai J, Gao Y, Song Z, Nauwynck H, Wang X, Yang Y, Jiang P
Journal of virology 2021 Aug 25;95(18):e0021021

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Hepatoprotective effect of anemoside B4 against sepsis-induced acute liver injury through modulating the mTOR/p70S6K-mediated autophagy.

Pei L, He L
Chemico-biological interactions 2021 Aug 25;345:109534

---

Ten-eleven translocation 1 mediated-DNA hydroxymethylation is required for myelination and remyelination in the mouse brain.

Zhang M, Wang J, Zhang K, Lu G, Liu Y, Ren K, Wang W, Xin D, Xu L, Mao H, Xing J, Gao X, Jin W, Berry K, Mikoshiba K, Wu S, Lu QR, Zhao X
Nature communications 2021 Aug 24;12(1):5091

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Circular RNA CircEYA3 induces energy production to promote pancreatic ductal adenocarcinoma progression through the miR-1294/c-Myc axis.

Rong Z, Shi S, Tan Z, Xu J, Meng Q, Hua J, Liu J, Zhang B, Wang W, Yu X, Liang C
Molecular cancer 2021 Aug 21;20(1):106

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HIF-1α-activated TM4SF1-AS1 promotes the proliferation, migration, and invasion of hepatocellular carcinoma cells by enhancing TM4SF1 expression.

Zeng Z, Shi Z, Liu Y, Zhao J, Lu Q, Guo J, Liu X, Huang D, Xu Q
Biochemical and biophysical research communications 2021 Aug 20;566:80-86

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Advanced oxidation protein products impair autophagic flux in macrophage by inducing lysosomal dysfunction via activation of PI3K-Akt-mTOR pathway in Crohn's disease.

Liao Y, Xu J, Qin B, Shi J, Qin C, Xie F, Ou S, Tang J, Wang W, Wu F, Bai L
Free radical biology & medicine 2021 Aug 20;172:33-47

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MicroRNA-138-1-3p sensitizes sorafenib to hepatocellular carcinoma by targeting PAK5 mediated β-catenin/ABCB1 signaling pathway.

Li TT, Mou J, Pan YJ, Huo FC, Du WQ, Liang J, Wang Y, Zhang LS, Pei DS
Journal of biomedical science 2021 Aug 2;28(1):56

---

The RNA m6A reader YTHDF2 controls NK cell antitumor and antiviral immunity.

Ma S, Yan J, Barr T, Zhang J, Chen Z, Wang LS, Sun JC, Chen J, Caligiuri MA, Yu J
The Journal of experimental medicine 2021 Aug 2;218(8)

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Polysaccharides from Ulva prolifera O.F. Müller inhibit cell proliferation via activating MAPK signaling in A549 and H1650 cells.

Yang JJ, Wang YH, Yin J, Leng H, Shen SD
Food & function 2021 Aug 2;12(15):6915-6924

---

Ceruloplasmin correlates with immune infiltration and serves as a prognostic biomarker in breast cancer.

Chen F, Han B, Meng Y, Han Y, Liu B, Zhang B, Chang Y, Cao P, Fan Y, Tan K
Aging 2021 Aug 19;13(16):20438-20467

---

Silibinin Suppresses Tumor Cell-Intrinsic Resistance to Nintedanib and Enhances Its Clinical Activity in Lung Cancer.

Bosch-Barrera J, Verdura S, Ruffinelli JC, Carcereny E, Sais E, Cuyàs E, Palmero R, Lopez-Bonet E, Hernández-Martínez A, Oliveras G, Buxó M, Izquierdo A, Morán T, Nadal E, Menendez JA
Cancers 2021 Aug 19;13(16)

---

Serum DJ-1 Is a Biomarker of Colorectal Cancer and DJ-1 Activates Mitophagy to Promote Colorectal Cancer Progression.

Chen WT, Yang HB, Ke TW, Liao WL, Hung SY
Cancers 2021 Aug 18;13(16)

---

Large-scale and high-resolution mass spectrometry-based proteomics profiling defines molecular subtypes of esophageal cancer for therapeutic targeting.

Liu W, Xie L, He YH, Wu ZY, Liu LX, Bai XF, Deng DX, Xu XE, Liao LD, Lin W, Heng JH, Xu X, Peng L, Huang QF, Li CY, Zhang ZD, Wang W, Zhang GR, Gao X, Wang SH, Li CQ, Xu LY, Liu W, Li EM
Nature communications 2021 Aug 16;12(1):4961

---

In vitro assessment of a synergistic combination of gemcitabine and zebularine in pancreatic cancer cells.

Patki M, Saraswat A, Bhutkar S, Dukhande V, Patel K
Experimental cell research 2021 Aug 15;405(2):112660

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Microtubule associated protein 4 (MAP4) phosphorylation reduces cardiac microvascular density through NLRP3-related pyroptosis.

Feng YH, Li LF, Zhang Q, Zhang JH, Huang Y, Lv YL, Jia JZ, Zhang D, Hu JY, Huang YS
Cell death discovery 2021 Aug 12;7(1):213

---

KAT2A-mediated AR translocation into nucleus promotes abiraterone-resistance in castration-resistant prostate cancer.

Lu D, Song Y, Yu Y, Wang D, Liu B, Chen L, Li X, Li Y, Cheng L, Lv F, Zhang P, Xing Y
Cell death & disease 2021 Aug 12;12(8):787

---

Metformin attenuates renal tubulointerstitial fibrosis via upgrading autophagy in the early stage of diabetic nephropathy.

Wang F, Sun H, Zuo B, Shi K, Zhang X, Zhang C, Sun D
Scientific reports 2021 Aug 11;11(1):16362

---

Nervous Necrosis Virus Coat Protein Mediates Host Translation Shutoff through Nuclear Translocalization and Degradation of Polyadenylate Binding Protein.

Cheng CA, Luo JM, Chiang MH, Fang KY, Li CH, Chen CW, Wang YS, Chang CY
Journal of virology 2021 Aug 10;95(17):e0236420

---

Ophiocordyceps lanpingensis polysaccharides alleviate chronic kidney disease through MAPK/NF-κB pathway.

Zhou S, He Y, Zhang W, Xiong Y, Jiang L, Wang J, Cui X, Qu Y, Ge F
Journal of ethnopharmacology 2021 Aug 10;276:114189

---

LncRNA LINC00680 promotes lung adenocarcinoma growth via binding to GATA6 and canceling GATA6-mediated suppression of SOX12 expression.

Sun X, Wang R, Tan M, Tian X, Meng J
Experimental cell research 2021 Aug 1;405(1):112653

---

Empagliflozin, a sodium glucose cotransporter-2 inhibitor, ameliorates peritoneal fibrosis via suppressing TGF-β/Smad signaling.

Shentu Y, Li Y, Xie S, Jiang H, Sun S, Lin R, Chen C, Bai Y, Zhang Y, Zheng C, Zhou Y
International immunopharmacology 2021 Apr;93:107374

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Ergosterol peroxide exhibits antiviral and immunomodulatory abilities against porcine deltacoronavirus (PDCoV) via suppression of NF-κB and p38/MAPK signaling pathways in vitro.

Duan C, Ge X, Wang J, Wei Z, Feng WH, Wang J
International immunopharmacology 2021 Apr;93:107317

---

LncRNA ABCC6P1 promotes proliferation and migration of papillary thyroid cancer cells via Wnt/β-catenin signaling pathway.

Guan Y, Li Y, Yang QB, Yu J, Qiao H
Annals of translational medicine 2021 Apr;9(8):664

---

Limonin induces apoptosis of HL-60 cells by inhibiting NQO1 activity.

Chen Y, Liang J, Liang X, Chen J, Wang Y, Cao J, Sun C, Ye J, Chen Q
Food science & nutrition 2021 Apr;9(4):1860-1869

---

Melatonin Ameliorates Lipopolysaccharide-Induced Microglial Inflammation via Triggering SIRT1/HMGB1 Signaling Axis.

Chibaatar E, Le K, Abdoulaye IA, Wu S, Guo Y
Journal of molecular neuroscience : MN 2021 Apr;71(4):691-701

---

Pooled CRISPR screening identifies m(6)A as a positive regulator of macrophage activation.

Tong J, Wang X, Liu Y, Ren X, Wang A, Chen Z, Yao J, Mao K, Liu T, Meng FL, Pan W, Zou Q, Liu J, Zhou Y, Xia Q, Flavell RA, Zhu S, Li HB
Science advances 2021 Apr;7(18)

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Bio-inspired chiral self-assemblies promoted neuronal differentiation of retinal progenitor cells through activation of metabolic pathway.

Sun N, Dou X, Tang Z, Zhang D, Ni N, Wang J, Gao H, Ju Y, Dai X, Zhao C, Gu P, Ji J, Feng C
Bioactive materials 2021 Apr;6(4):990-997

---

Perilipin 4 Protein: an Impending Target for Amyotrophic Lateral Sclerosis.

Zhu L, Hu F, Li C, Zhang C, Hang R, Xu R
Molecular neurobiology 2021 Apr;58(4):1723-1737

---

Inhibition of soluble epoxide hydrolase (sEH) protects hippocampal neurons and reduces cognitive decline in type 2 diabetic mice.

Wu J, Fan Z, Zhao Y, Chen Q, Xiao Q
The European journal of neuroscience 2021 Apr;53(8):2532-2540

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Let-7 mediated airway remodelling in chronic obstructive pulmonary disease via the regulation of IL-6.

Di T, Yang Y, Fu C, Zhang Z, Qin C, Sai X, Liu J, Hu C, Zheng M, Wu Y, Bian T
European journal of clinical investigation 2021 Apr;51(4):e13425

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Expression of lncRNA CCAT2 in children with neuroblastoma and its effect on cancer cell growth.

Chen M, Zhao M, Hou Y, Zhu B
Molecular and cellular biochemistry 2021 Apr;476(4):1871-1879

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Induction of NUPR1 and AP‑1 contributes to the carcinogenic potential of nickel.

Murphy A, Roy N, Sun H, Jin C, Costa M
Oncology reports 2021 Apr;45(4)

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Anti-thrombotic activity of phenolic acids obtained from Salvia miltiorrhiza f. alba in TNF-α-stimulated endothelial cells via the NF-κB/JNK/p38 MAPK signaling pathway.

Zheng X, Liu H, Ma M, Ji J, Zhu F, Sun L
Archives of pharmacal research 2021 Apr;44(4):427-438

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miR-182-5p and miR-96-5p Target PIAS1 and Mediate the Negative Feedback Regulatory Loop between PIAS1 and STAT3 in Endometrial Cancer.

Xiao Y, Huang W, Huang H, Wang L, Wang M, Zhang T, Fang X, Xia X
DNA and cell biology 2021 Apr;40(4):618-628

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CRISPR/Cas9 library screening uncovered methylated PKP2 as a critical driver of lung cancer radioresistance by stabilizing β-catenin.

Cheng C, Pei X, Li SW, Yang J, Li C, Tang J, Hu K, Huang G, Min WP, Sang Y
Oncogene 2021 Apr;40(16):2842-2857

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The orphan nuclear receptor Nurr1 agonist amodiaquine mediates neuroprotective effects in 6-OHDA Parkinson's disease animal model by enhancing the phosphorylation of P38 mitogen-activated kinase but not PI3K/AKT signaling pathway.

Kambey PA, Chengcheng M, Xiaoxiao G, Abdulrahman AA, Kanwore K, Nadeem I, Jiao W, Gao D
Metabolic brain disease 2021 Apr;36(4):609-625

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Programmed cell death 4 modulates lysosomal function by inhibiting TFEB translation.

Chen X, Guan Y, Zhang Y, Jia Y, Li W, Guo C, Li Y, Wang X, Shi Y, Wang Q, Zhu F, Li Y, Zhang L
Cell death and differentiation 2021 Apr;28(4):1237-1250

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ARFGAP1 binds to classical swine fever virus NS5A protein and enhances CSFV replication in PK-15 cells.

Zhang L, Jin M, Song M, Liu S, Wang T, Guo K, Zhang Y
Veterinary microbiology 2021 Apr;255:109034

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MARCH5 restores endothelial cell function against ischaemic/hypoxia injury via Akt/eNOS pathway.

Lei W, Li J, Li C, Chen L, Huang F, Xiao D, Zhang J, Zhao J, Li G, Qu T, Zhou H, Liao Y, Chen M
Journal of cellular and molecular medicine 2021 Apr;25(7):3182-3193

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Method used to establish a large animal model of drug-induced acute kidney injury.

Wang SY, Zhang CY, Cai GY, Chen XM
Experimental biology and medicine (Maywood, N.J.) 2021 Apr;246(8):986-995

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Postnatal growth retardation is associated with deteriorated intestinal mucosal barrier function using a porcine model.

Qi M, Tan B, Wang J, Liao S, Li J, Cui Z, Shao Y, Ji P, Yin Y
Journal of cellular physiology 2021 Apr;236(4):2631-2648

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[Effect of astragaloside IV on the expression of NOD-like receptor protein 3 inflammasome in neonatal rats with hypoxic-ischemic brain damage].

Li N, Mu YP, Liu CY, Wang Y, Li XF, Wang XW
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 2021 Apr;23(4):402-409

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LncIHAT Is Induced by Hypoxia-Inducible Factor 1 and Promotes Breast Cancer Progression.

Chen L, Bao L, Niu Y, Wang JE, Kumar A, Xing C, Wang Y, Luo W
Molecular cancer research : MCR 2021 Apr;19(4):678-687

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Cigarette smoke extract amplifies NADPH oxidase-dependent ROS production to inactivate PTEN by oxidation in BEAS-2B cells.

Cai B, Liu M, Li J, Xu D, Li J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Apr;150:112050

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Low-dose naltrexone plays antineoplastic role in cervical cancer progression through suppressing PI3K/AKT/mTOR pathway.

Liu N, Yan L, Shan F, Wang X, Qu N, Handley MK, Ma M
Translational oncology 2021 Apr;14(4):101028

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The S100 calcium-binding protein A11 promotes hepatic steatosis through RAGE-mediated AKT-mTOR signaling.

Teng F, Jiang J, Zhang J, Yuan Y, Li K, Zhou B, Zhou X, Liu W, Zhang P, Liu D, Zheng M, Lu Y, Zhang H
Metabolism: clinical and experimental 2021 Apr;117:154725

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Resveratrol Attenuates Meningitic Escherichia coli-Mediated Blood-Brain Barrier Disruption.

Yang R, Lv Y, Miao L, Zhang H, Qu X, Chen J, Xu B, Yang B, Fu J, Tan C, Chen H, Wang X
ACS infectious diseases 2021 Apr 9;7(4):777-789

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PolyQ-expanded proteins impair cellular proteostasis of ataxin-3 through sequestering the co-chaperone HSJ1 into aggregates.

Yue HW, Hong JY, Zhang SX, Jiang LL, Hu HY
Scientific reports 2021 Apr 9;11(1):7815

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N(6)-methyladenosine-binding protein YTHDF1 suppresses EBV replication and promotes EBV RNA decay.

Xia TL, Li X, Wang X, Zhu YJ, Zhang H, Cheng W, Chen ML, Ye Y, Li Y, Zhang A, Dai DL, Zhu QY, Yuan L, Zheng J, Huang H, Chen SQ, Xiao ZW, Wang HB, Roy G, Zhong Q, Lin D, Zeng YX, Wang J, Zhao B, Gewurz BE, Chen J, Zuo Z, Zeng MS
EMBO reports 2021 Apr 7;22(4):e50128

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ASIC1 and ASIC3 mediate cellular senescence of human nucleus pulposus mesenchymal stem cells during intervertebral disc degeneration.

Ding J, Zhang R, Li H, Ji Q, Cheng X, Thorne RF, Hondermarck H, Liu X, Shen C
Aging 2021 Apr 6;13(7):10703-10723

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EGFR-ERK induced activation of GRHL1 promotes cell cycle progression by up-regulating cell cycle related genes in lung cancer.

He Y, Gan M, Wang Y, Huang T, Wang J, Han T, Yu B
Cell death & disease 2021 Apr 30;12(5):430

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miR-190 promotes malignant transformation and progression of human urothelial cells through CDKN1B/p27 inhibition.

Huang S, Hua X, Kuang M, Zhu J, Mu H, Tian Z, Zheng X, Xie Q
Cancer cell international 2021 Apr 29;21(1):241

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Pterostilbene, a Dimethylether Analogue of Resveratrol, Possesses High Potency in the Prevention of Platelet Activation in Humans and the Reduction of Vascular Thrombosis in Mice.

Huang WC, Liu JC, Hsia CW, Fong TH, Hsia CH, Tran OT, Velusamy M, Yang CH, Sheu JR
Journal of agricultural and food chemistry 2021 Apr 28;69(16):4697-4707

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Fludarabine Inhibits Infection of Zika Virus, SFTS Phlebovirus, and Enterovirus A71.

Gao C, Wen C, Li Z, Lin S, Gao S, Ding H, Zou P, Xing Z, Yu Y
Viruses 2021 Apr 27;13(5)

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Dynamic evolution of emphysema and airway remodeling in two mouse models of COPD.

Yang Y, Di T, Zhang Z, Liu J, Fu C, Wu Y, Bian T
BMC pulmonary medicine 2021 Apr 26;21(1):134

---

Leukemia inhibitory factor regulates Schwann cell proliferation and migration and affects peripheral nerve regeneration.

Chen Q, Liu Q, Zhang Y, Li S, Yi S
Cell death & disease 2021 Apr 22;12(5):417

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Circ11103 Interacts with miR-128/PPARGC1A to Regulate Milk Fat Metabolism in Dairy Cows.

Chen Z, Lu Q, Liang Y, Cui X, Wang X, Mao Y, Yang Z
Journal of agricultural and food chemistry 2021 Apr 21;69(15):4490-4500

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H(2)O(2) enhances the anticancer activity of TMPyP4 by ROS-mediated mitochondrial dysfunction and DNA damage.

Chen J, Jin X, Shen Z, Mei Y, Zhu J, Zhang X, Liang G, Zheng X
Medical oncology (Northwood, London, England) 2021 Apr 21;38(6):59

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Buprenorphine alters microglia and astrocytes acutely following diffuse traumatic brain injury.

Ryu J, Stone P, Lee S, Payne B, Gorse K, Lafrenaye A
Scientific reports 2021 Apr 21;11(1):8620

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CK2 Activity Mediates the Aggressive Molecular Signature of Glioblastoma Multiforme by Inducing Nerve/Glial Antigen (NG)2 Expression.

Schmitt BM, Boewe AS, Götz C, Philipp SE, Urbschat S, Oertel J, Menger MD, Laschke MW, Ampofo E
Cancers 2021 Apr 2;13(7)

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Identification of a mesenchymal-related signature associated with clinical prognosis in glioma.

Zhang Z, Chen J, Huo X, Zong G, Huang K, Cheng M, Sun L, Yue X, Bian E, Zhao B
Aging 2021 Apr 19;13(9):12431-12455

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Btk knockout attenuates the liver inflammation in STZ-induced diabetic mice by suppressing NLRP3 inflammasome activation.

Li Y, Zhao J, Wu Y, Xia L
Biochemical and biophysical research communications 2021 Apr 16;549:75-82

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Chemoproteomics-enabled discovery of covalent RNF114-based degraders that mimic natural product function.

Luo M, Spradlin JN, Boike L, Tong B, Brittain SM, McKenna JM, Tallarico JA, Schirle M, Maimone TJ, Nomura DK
Cell chemical biology 2021 Apr 15;28(4):559-566.e15

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Loss of Mitochondrial Protease CLPP Activates Type I IFN Responses through the Mitochondrial DNA-cGAS-STING Signaling Axis.

Torres-Odio S, Lei Y, Gispert S, Maletzko A, Key J, Menissy SS, Wittig I, Auburger G, West AP
Journal of immunology (Baltimore, Md. : 1950) 2021 Apr 15;206(8):1890-1900

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AKR1B10 negatively regulates autophagy through reducing GAPDH upon glucose starvation in colon cancer.

Li W, Liu C, Huang Z, Shi L, Zhong C, Zhou W, Meng P, Li Z, Wang S, Luo F, Yan J, Wu T
Journal of cell science 2021 Apr 15;134(8)

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Kisspeptin-10 Maintains the Activation of the mTOR Signaling Pathway by Inhibiting SIRT6 to Promote the Synthesis of Milk in Bovine Mammary Epithelial Cells.

Cao Y, Hu G, Zhang Q, Ma L, Wang J, Li W, Ge Y, Cheng J, Yang Z, Fu S, Liu J
Journal of agricultural and food chemistry 2021 Apr 14;69(14):4093-4100

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AIF3 splicing switch triggers neurodegeneration.

Liu S, Zhou M, Ruan Z, Wang Y, Chang C, Sasaki M, Rajaram V, Lemoff A, Nambiar K, Wang JE, Hatanpaa KJ, Luo W, Dawson TM, Dawson VL, Wang Y
Molecular neurodegeneration 2021 Apr 14;16(1):25

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An Experimentally Induced Mutation in the UBA Domain of p62 Changes the Sensitivity of Cisplatin by Up-Regulating HK2 Localisation on the Mitochondria and Increasing Mitophagy in A2780 Ovarian Cancer Cells.

Yu S, Yan X, Tian R, Xu L, Zhao Y, Sun L, Su J
International journal of molecular sciences 2021 Apr 13;22(8)

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Nonsegmented Negative-Sense RNA Viruses Utilize N(6)-Methyladenosine (m(6)A) as a Common Strategy To Evade Host Innate Immunity.

Lu M, Xue M, Wang HT, Kairis EL, Ahmad S, Wei J, Zhang Z, Liu Q, Zhang Y, Gao Y, Garcin D, Peeples ME, Sharma A, Hur S, He C, Li J
Journal of virology 2021 Apr 12;95(9)

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Kaempferol induces ROS-dependent apoptosis in pancreatic cancer cells via TGM2-mediated Akt/mTOR signaling.

Wang F, Wang L, Qu C, Chen L, Geng Y, Cheng C, Yu S, Wang D, Yang L, Meng Z, Chen Z
BMC cancer 2021 Apr 12;21(1):396

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Effect of Shuangdan Mingmu capsule, a Chinese herbal formula, on oxidative stress-induced apoptosis of pericytes through PARP/GAPDH pathway.

Nie F, Yan J, Ling Y, Liu Z, Fu C, Li X, Qin Y
BMC complementary medicine and therapies 2021 Apr 10;21(1):118

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TET1 may contribute to hypoxia-induced epithelial to mesenchymal transition of endometrial epithelial cells in endometriosis.

Wu J, Li X, Huang H, Xia X, Zhang M, Fang X
PeerJ 2020;8:e9950

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Lycopene alleviates oxidative stress via the PI3K/Akt/Nrf2pathway in a cell model of Alzheimer's disease.

Fang Y, Ou S, Wu T, Zhou L, Tang H, Jiang M, Xu J, Guo K
PeerJ 2020;8:e9308

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Tethering of Telomeres to the Nuclear Envelope Is Mediated by SUN1-MAJIN and Possibly Promoted by SPDYA-CDK2 During Meiosis.

Wang G, Wu X, Zhou L, Gao S, Yun D, Liang A, Sun F
Frontiers in cell and developmental biology 2020;8:845

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Enterohemorrhagic Escherichia coli Effector Protein EspF Interacts With Host Protein ANXA6 and Triggers Myosin Light Chain Kinase (MLCK)-Dependent Tight Junction Dysregulation.

Hua Y, Wu J, Fu M, Liu J, Li X, Zhang B, Zhao W, Wan C
Frontiers in cell and developmental biology 2020;8:613061

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Safrana l Prevents Prostate Cancer Recurrence by Blocking the Re-activation of Quiescent Cancer Cells via Downregulation of S-Phase Kinase-Associated Protein 2.

Jiang X, Li Y, Feng JL, Nik Nabil WN, Wu R, Lu Y, Liu H, Xi ZC, Xu HX
Frontiers in cell and developmental biology 2020;8:598620

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miR-7-5p Affects Brain Edema After Intracerebral Hemorrhage and Its Possible Mechanism.

Chen X, Deng S, Lei Q, He Q, Ren Y, Zhang Y, Nie J, Lu W
Frontiers in cell and developmental biology 2020;8:598020

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Amnion-Derived Mesenchymal Stem Cell Exosomes-Mediated Autophagy Promotes the Survival of Trophoblasts Under Hypoxia Through mTOR Pathway by the Downregulation of EZH2.

Chu Y, Chen W, Peng W, Liu Y, Xu L, Zuo J, Zhou J, Zhang Y, Zhang N, Li J, Liu L, Yao K, Gao G, Wang X, Han R, Liu C, Li Y, Zhou H, Huang Y, Ye Y
Frontiers in cell and developmental biology 2020;8:545852

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C2C12 Mouse Myoblasts Damage Induced by Oxidative Stress Is Alleviated by the Antioxidant Capacity of the Active Substance Phloretin.

Li J, Yang Q, Han L, Pan C, Lei C, Chen H, Lan X
Frontiers in cell and developmental biology 2020;8:541260

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Ferroptosis-Related Gene Signature Predicts Glioma Cell Death and Glioma Patient Progression.

Liu HJ, Hu HM, Li GZ, Zhang Y, Wu F, Liu X, Wang KY, Zhang CB, Jiang T
Frontiers in cell and developmental biology 2020;8:538

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miR-205 Expression Elevated With EDS Treatment and Induced Leydig Cell Apoptosis by Targeting RAP2B via the PI3K/AKT Signaling Pathway.

Cui Y, Chen R, Ma L, Yang W, Chen M, Zhang Y, Yu S, Dong W, Zeng W, Lan X, Pan C
Frontiers in cell and developmental biology 2020;8:448

---

Ketamine ameliorates hypoxia-induced endothelial injury in human umbilical vein endothelial cells.

Zhou X, Liu J, Yang S, Su Y, Meng Z, Hu Y
Clinics (Sao Paulo, Brazil) 2020;75:e1865

---

Cdk5 Inhibitory Peptide Prevents Loss of Neurons and Alleviates Behavioral Changes in p25 Transgenic Mice.

Huang Y, Huang W, Huang Y, Song P, Zhang M, Zhang HT, Pan S, Hu Y
Journal of Alzheimer's disease : JAD 2020;74(4):1231-1242

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Maternal Methyl-Donor Micronutrient Supplementation During Pregnancy Promotes Skeletal Muscle Differentiation and Maturity in Newborn and Weaning Pigs.

He Q, Zou T, Chen J, Jian L, He J, Xia Y, Xie F, Wang Z, You J
Frontiers in nutrition 2020;7:609022

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Potential Role of SLC5A8 Expression in the Etiology of Subacute Ruminal Acidosis.

Zhao C, Bobe G, Wang Y, Zhang X, Zhao Z, Zhang S, Sun G, Yuan X, Li X, Liu G
Frontiers in veterinary science 2020;7:394

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miR-124-3p Suppresses the Invasiveness and Metastasis of Hepatocarcinoma Cells via Targeting CRKL.

Majid A, Wang J, Nawaz M, Abdul S, Ayesha M, Guo C, Liu Q, Liu S, Sun MZ
Frontiers in molecular biosciences 2020;7:223

---

MicroRNA-362-3p Inhibits Migration and Invasion via Targeting BCAP31 in Cervical Cancer.

Yang S, Zhang X, Sun Y, Shi J, Jiang D, Wang J, Liu Y, Hu C, Pan J, Zheng L, Yang K
Frontiers in molecular biosciences 2020;7:107

---

Metformin effectively treats Tsc1 deletion-caused kidney pathology by upregulating AMPK phosphorylation.

Fang Y, Li F, Qi C, Mao X, Wang F, Zhao Z, Chen JK, Zhang Z, Wu H
Cell death discovery 2020;6:52

---

miR-143-3p inhibition promotes neuronal survival in an Alzheimer's disease cell model by targeting neuregulin-1.

Sun C, Jia N, Li R, Zhang Z, Zhong Y, Han K
Folia neuropathologica 2020;58(1):10-21

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Modulation of Wnt/β-catenin signaling in IL-17A-mediated macrophage polarization of RAW264.7 cells.

Yuan C, Yang D, Ma J, Yang J, Xue J, Song F, Liu X
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2020;53(8):e9488

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Antrodia Cinnamomea Attenuates Non-Alcoholic Steatohepatitis by Suppressing NLRP3 Inflammasome Activation In Vitro and In Vivo.

Yen IC, Lin JC, Chen Y, Tu QW, Lee SY
The American journal of Chinese medicine 2020;48(8):1859-1874

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Koumine Alleviates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction in IPEC-J2 Cells by Regulating Nrf2/NF-κB Pathway.

Wu J, Yang CL, Sha YK, Wu Y, Liu ZY, Yuan ZH, Sun ZL
The American journal of Chinese medicine 2020;48(1):127-142

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Osthole Improves Cognitive Function of Vascular Dementia Rats: Reducing Aβ Deposition via Inhibition NLRP3 Inflammasome.

Liu Y, Chen X, Gong Q, Shi J, Li F
Biological & pharmaceutical bulletin 2020;43(9):1315-1323

---

Dietary Baicalin Zinc Supplementation Alleviates Oxidative Stress and Enhances Nutrition Absorption in Deoxynivalenol Challenged Pigs.

Zha A, Cui Z, Qi M, Liao S, Chen L, Liao P, Tan B
Current drug metabolism 2020;21(8):614-625

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Heme Oxygenase-1-Mediated Autophagy Protects against Oxidative Damage in Rat Nucleus Pulposus-Derived Mesenchymal Stem Cells.

Chen S, Liu S, Zhao L, Lin H, Ma K, Shao Z
Oxidative medicine and cellular longevity 2020;2020:9349762

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Environmental Pollutant Benzo[a]pyrene Induces Recurrent Pregnancy Loss through Promoting Apoptosis and Suppressing Migration of Extravillous Trophoblast.

Ye Y, Jiang S, Zhang C, Cheng Y, Zhong H, Du T, Xu W, Azziz R, Zhang H, Zhao X
BioMed research international 2020;2020:8983494

---

Disease Mutation Study Identifies Critical Residues for Phosphatidylserine Flippase ATP11A.

Sun K, Tian W, Li X, Liu W, Yang Y, Zhu X
BioMed research international 2020;2020:7342817

---

Rhein Suppresses Neuroinflammation via Multiple Signaling Pathways in LPS-Stimulated BV2 Microglia Cells.

Zheng P, Tian X, Zhang W, Yang Z, Zhou J, Zheng J, Cui H, Tang T, Luo J, Wang Y
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7210627

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Hydrogen Gas Attenuates Hypoxic-Ischemic Brain Injury via Regulation of the MAPK/HO-1/PGC-1a Pathway in Neonatal Rats.

Wang P, Zhao M, Chen Z, Wu G, Fujino M, Zhang C, Zhou W, Zhao M, Hirano SI, Li XK, Zhao L
Oxidative medicine and cellular longevity 2020;2020:6978784

---

Human Tissue Kallikrein 1 Improves Erectile Dysfunction of Streptozotocin-Induced Diabetic Rats by Inhibition of Excessive Oxidative Stress and Activation of the PI3K/AKT/eNOS Pathway.

Luan Y, Cui K, Tang Z, Ruan Y, Liu K, Wang T, Chen Z, Wang S, Liu J
Oxidative medicine and cellular longevity 2020;2020:6834236

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Bergenin Attenuates Hepatic Fibrosis by Regulating Autophagy Mediated by the PPAR-γ/TGF-β Pathway.

Xia Y, Li J, Chen K, Feng J, Guo C
PPAR research 2020;2020:6694214

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Hyperglycemia Induces Endoplasmic Reticulum Stress in Atrial Cardiomyocytes, and Mitofusin-2 Downregulation Prevents Mitochondrial Dysfunction and Subsequent Cell Death.

Yuan M, Gong M, Zhang Z, Meng L, Tse G, Zhao Y, Bao Q, Zhang Y, Yuan M, Liu X, Li G, Liu T
Oxidative medicine and cellular longevity 2020;2020:6569728

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Mild Hypothermia Attenuates Hepatic Ischemia-Reperfusion Injury through Regulating the JAK2/STAT3-CPT1a-Dependent Fatty Acid β-Oxidation.

Wang W, Hu X, Xia Z, Liu Z, Zhong Z, Lu Z, Liu A, Ye S, Cao Q, Wang Y, Zhu F, Ye Q
Oxidative medicine and cellular longevity 2020;2020:5849794

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Dexmedetomidine Attenuates Neurotoxicity in Developing Rats Induced by Sevoflurane through Upregulating BDNF-TrkB-CREB and Downregulating ProBDNF-P75NRT-RhoA Signaling Pathway.

Dong Y, Hong W, Tang Z, Gao Y, Wu X, Liu H
Mediators of inflammation 2020;2020:5458061

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NLRC3 Delays the Progression of AD in APP/PS1 Mice via Inhibiting PI3K Activation.

Zha L, Yu Z, Fang J, Zhou L, Guo W, Zhou J
Oxidative medicine and cellular longevity 2020;2020:5328031

---

Qingjie Fuzheng Granule Inhibited the Migration and Invasion of Colorectal Cancer Cells by Regulating the lncRNA ANRIL/let-7a/TGF-β1/Smad Axis.

Zhang L, Liu J, Lin S, Tan J, Huang B, Lin J
Evidence-based complementary and alternative medicine : eCAM 2020;2020:5264651

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The Nrf2/PGC1α Pathway Regulates Antioxidant and Proteasomal Activity to Alter Cisplatin Sensitivity in Ovarian Cancer.

Deng X, Lin N, Fu J, Xu L, Luo H, Jin Y, Liu Y, Sun L, Su J
Oxidative medicine and cellular longevity 2020;2020:4830418

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Congrong Shujing Granule-Induced GRP78 Expression Reduced Endoplasmic Reticulum Stress and Neuronal Apoptosis in the Midbrain in a Parkinson's Disease Rat Model.

Xu Q, Yang S, Wu F, Lin Y, Zhong J, Tang L, Hu X, Cai J
Evidence-based complementary and alternative medicine : eCAM 2020;2020:4796236

---

LncRNA CAR10 Upregulates PDPK1 to Promote Cervical Cancer Development by Sponging miR-125b-5p.

Hu T, Zhang Q, Gao L
BioMed research international 2020;2020:4351671

---

Fasting Induces Hepatocellular Carcinoma Cell Apoptosis by Inhibiting SET8 Expression.

Qi J, Chen X, Wu Q, Wang J, Zhang H, Mao A, Zhu M, Miao C
Oxidative medicine and cellular longevity 2020;2020:3985089

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Tyrosine Kinase Receptors Axl and MerTK Mediate the Beneficial Effect of Electroacupuncture in a Cuprizone-Induced Demyelinating Model.

Zou Z, Sun J, Kang Z, Wang Y, Zhao H, Zhu K, Wang J
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3205176

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Gubenzhike Recipe Ameliorates Respiratory Mucosal Immunity in Mice with Chronic Obstructive Pulmonary Disease through Upregulation of the γδT Lymphocytes and KGF Levels.

Wang YQ, Liao Q, Tang SH, Cai Z, Zhang HC
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3056797

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Hypouricemic Effects of Extracts from Urtica hyperborea Jacq. ex Wedd. in Hyperuricemia Mice through XOD, URAT1, and OAT1.

Han S, Wei R, Han D, Zhu J, Luo W, Ao W, Zhong G
BioMed research international 2020;2020:2968135

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Gentiopicroside Ameliorates Oxidative Stress and Lipid Accumulation through Nuclear Factor Erythroid 2-Related Factor 2 Activation.

Jin M, Feng H, Wang Y, Yan S, Shen B, Li Z, Qin H, Wang Q, Li J, Liu G
Oxidative medicine and cellular longevity 2020;2020:2940746

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Mechanisms of Cong Rong Shu Jing Compound Effects on Endoplasmic Reticulum Stress in a Rat Model of Parkinson's Disease.

Lin Y, Tang L, Huang P, Liu T, Zhong J, Xu Q, Li X, Lin Y, Xiao S, Cai J
Evidence-based complementary and alternative medicine : eCAM 2020;2020:1818307

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N-Butanol Extract of Gastrodia elata Suppresses Inflammatory Responses in Lipopolysaccharide-Stimulated Macrophages and Complete Freund's Adjuvant- (CFA-) Induced Arthritis Rats via Inhibition of MAPK Signaling Pathway.

He P, Hu Y, Huang C, Wang X, Zhang H, Zhang X, Dai H, Wang R, Gao Y
Evidence-based complementary and alternative medicine : eCAM 2020;2020:1658618

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Effect of Thymoquinone on Acute Kidney Injury Induced by Sepsis in BALB/c Mice.

Guo LP, Liu SX, Yang Q, Liu HY, Xu LL, Hao YH, Zhang XQ
BioMed research international 2020;2020:1594726

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HuR Affects Proliferation and Apoptosis of Chronic Lymphocytic Leukemia Cells via NF-κB Pathway.

Xiao K, Yang L, Gao X, An Y, Xie W, Jingquan G
BioMed research international 2020;2020:1481572

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Azelaic Acid Exerts Antileukemia Effects against Acute Myeloid Leukemia by Regulating the Prdxs/ROS Signaling Pathway.

Zhang D, Luo Z, Jin Y, Chen Y, Yang T, Yang Q, Wu B, Shang Y, Liu X, Wei Y, Zhou F
Oxidative medicine and cellular longevity 2020;2020:1295984

---

Melatonin Alleviates Neuroinflammation and Metabolic Disorder in DSS-Induced Depression Rats.

Lv WJ, Liu C, Yu LZ, Zhou JH, Li Y, Xiong Y, Guo A, Chao LM, Qu Q, Wei GW, Tang XG, Yin YL, Guo SN
Oxidative medicine and cellular longevity 2020;2020:1241894

---

Suppression of NLRP3 Inflammasome, Pyroptosis, and Cell Death by NIM811 in Rotenone-Exposed Cells as an in vitro Model of Parkinson's Disease.

Zhang M, He Q, Chen G, Li PA
Neuro-degenerative diseases 2020;20(2-3):73-83

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MiR-1307-5p targeting TRAF3 upregulates the MAPK/NF-κB pathway and promotes lung adenocarcinoma proliferation.

Du X, Wang S, Liu X, He T, Lin X, Wu S, Wang D, Li J, Huang W, Yang H
Cancer cell international 2020;20:502

---

XIST lost induces ovarian cancer stem cells to acquire taxol resistance via a KMT2C-dependent way.

Huang R, Zhu L, Zhang Y
Cancer cell international 2020;20:436

---

TET1 promotes fatty acid oxidation and inhibits NAFLD progression by hydroxymethylation of PPARα promoter.

Wang J, Zhang Y, Zhuo Q, Tseng Y, Wang J, Ma Y, Zhang J, Liu J
Nutrition & metabolism 2020;17:46

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Integrin α1 promotes tumorigenicity and progressive capacity of colorectal cancer.

Li H, Wang Y, Rong SK, Li L, Chen T, Fan YY, Wang YF, Yang CR, Yang C, Cho WC, Yang J
International journal of biological sciences 2020;16(5):815-826

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PFKP is transcriptionally repressed by BRCA1/ZBRK1 and predicts prognosis in breast cancer.

Yeerken D, Hong R, Wang Y, Gong Y, Liu R, Yang D, Li J, Fan J, Chen J, Zhang W, Zhan Q
PloS one 2020;15(5):e0233750

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Structure-function analyses of candidate small molecule RPN13 inhibitors with antitumor properties.

Anchoori RK, Tan M, Tseng SH, Peng S, Soong RS, Algethami A, Foran P, Das S, Wang C, Wang TL, Liang H, Hung CF, Roden RBS
PloS one 2020;15(1):e0227727

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Jia-Ji Electro-Acupuncture Improves Locomotor Function With Spinal Cord Injury by Regulation of Autophagy Flux and Inhibition of Necroptosis.

Hongna Y, Hongzhao T, Quan L, Delin F, Guijun L, Xiaolin L, Fulin G, Zhongren S
Frontiers in neuroscience 2020;14:616864

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Hydrogen Sulfide Overproduction Is Involved in Acute Ischemic Cerebral Injury Under Hyperhomocysteinemia.

Ji Y, Li Y, Zhao Z, Li P, Xie Y
Frontiers in neuroscience 2020;14:582851

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Olfactory Mucosa Mesenchymal Stem Cells Ameliorate Cerebral Ischemic/Reperfusion Injury Through Modulation of UBIAD1 Expression.

Liu J, Huang Y, He J, Zhuo Y, Chen W, Ge L, Duan D, Lu M, Hu Z
Frontiers in cellular neuroscience 2020;14:580206

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Differences in DNA Methylation Reprogramming Underlie the Sexual Dimorphism of Behavioral Disorder Caused by Prenatal Stress in Rats.

Lei L, Wu X, Gu H, Ji M, Yang J
Frontiers in neuroscience 2020;14:573107

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iTRAQ-Based Quantitative Proteomic Analysis of Intestines in Murine Polymicrobial Sepsis with Hydrogen Gas Treatment.

Jiang Y, Bian Y, Lian N, Wang Y, Xie K, Qin C, Yu Y
Drug design, development and therapy 2020;14:4885-4900

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Identification of a Novel c-Myc Inhibitor 7594-0037 by Structure-Based Virtual Screening and Investigation of Its Anti-Cancer Effect on Multiple Myeloma.

Yao R, Xie Y, Sun X, Zhang M, Zhou J, Liu L, Gao J, Xu K
Drug design, development and therapy 2020;14:3983-3993

---

The Potential Effects of Aliskiren on Atrial Remodeling Induced by Chronic Intermittent Hypoxia in Rats.

Miao S, Yang Y, Li R, Yin L, Zhang K, Cheng L, Xu X, Wang W, Zhao Z, Li G
Drug design, development and therapy 2020;14:3755-3764

---

Electro-Acupuncture Promotes the Differentiation of Endogenous Neural Stem Cells via Exosomal microRNA 146b After Ischemic Stroke.

Zhang S, Jin T, Wang L, Liu W, Zhang Y, Zheng Y, Lin Y, Yang M, He X, Lin H, Chen L, Tao J
Frontiers in cellular neuroscience 2020;14:223

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Paeoniflorin Ameliorates Chronic Hypoxia/SU5416-Induced Pulmonary Arterial Hypertension by Inhibiting Endothelial-to-Mesenchymal Transition.

Yu M, Peng L, Liu P, Yang M, Zhou H, Ding Y, Wang J, Huang W, Tan Q, Wang Y, Xie W, Kong H, Wang H
Drug design, development and therapy 2020;14:1191-1202

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The knockdown of the sepiapterin reductase gene suppresses the proliferation of breast cancer by inducing ROS-mediated apoptosis.

Zhang X, Chen Y, Wang K, Tang J, Chen Y, Jin G, Liu X
International journal of clinical and experimental pathology 2020;13(9):2228-2239

---

Chaetomugilin J Enhances Apoptosis in Human Ovarian Cancer A2780 Cells Induced by Cisplatin Through Inhibiting Pink1/Parkin Mediated Mitophagy.

Hu X, Wang J, Chai J, Yu X, Zhang Y, Feng Y, Qin J, Yu H
OncoTargets and therapy 2020;13:9967-9976

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MicroRNA-623 Inhibits Epithelial-Mesenchymal Transition to Attenuate Glioma Proliferation by Targeting TRIM44.

Cui D, Wang K, Liu Y, Gao J, Cui J
OncoTargets and therapy 2020;13:9291-9303

---

Excessive Treadmill Training Enhances Brain-Specific MicroRNA-34a in the Mouse Hippocampus.

Xu L, Zheng YL, Yin X, Xu SJ, Tian D, Zhang CY, Wang S, Ma JZ
Frontiers in molecular neuroscience 2020;13:7

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Chronic Intermittent Hypobaric Hypoxia Restores Hippocampus Function and Rescues Cognitive Impairments in Chronic Epileptic Rats via Wnt/β-catenin Signaling.

Sun C, Fu J, Qu Z, Jia L, Li D, Zhen J, Wang W
Frontiers in molecular neuroscience 2020;13:617143

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β-Elemene Enhances the Chemotherapeutic Effect of 5-Fluorouracil in Triple-Negative Breast Cancer via PI3K/AKT, RAF-MEK-ErK, and NF-κB Signaling Pathways.

Su P, Ahmad B, Zou K, Zou L
OncoTargets and therapy 2020;13:5207-5222

---

Elevated Levels of circRUNX1 in Colorectal Cancer Promote Cell Growth and Metastasis via miR-145-5p/IGF1 Signalling.

Chen ZL, Li XN, Ye CX, Chen HY, Wang ZJ
OncoTargets and therapy 2020;13:4035-4048

---

Microsatellite Instability-Related ACVR2A Mutations Partially Account for Decreased Lymph Node Metastasis in MSI-H Gastric Cancers.

Zhao L, Zhang J, Qu X, Yang Y, Gong Z, Yang Y, Wu Z, Guo W
OncoTargets and therapy 2020;13:3809-3821

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Long Noncoding RNA NEAT1 Upregulates Survivin and Facilitates Gallbladder Cancer Progression by Sponging microRNA-335.

Yang F, Tang Z, Duan A, Yi B, Shen N, Bo Z, Yin L, Zhu B, Qiu Y, Li J
OncoTargets and therapy 2020;13:2357-2367

---

Alpha1-Antitrypsin in Urinary Extracellular Vesicles: A Potential Biomarker of Diabetic Kidney Disease Prior to Microalbuminuria.

Ning J, Xiang Z, Xiong C, Zhou Q, Wang X, Zou H
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:2037-2048

---

Empagliflozin Protects Against Proximal Renal Tubular Cell Injury Induced by High Glucose via Regulation of Hypoxia-Inducible Factor 1-Alpha.

Ndibalema AR, Kabuye D, Wen S, Li L, Li X, Fan Q
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:1953-1967

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Simultaneous Inhibition of Ornithine Decarboxylase 1 and Pyruvate Kinase M2 Exerts Synergistic Effects Against Hepatocellular Carcinoma Cells.

Zeng Z, Lan J, Lei S, Yang Y, He Z, Xue Y, Chen T
OncoTargets and therapy 2020;13:11697-11709

---

MiR-935/HIF1α Feedback Loop Inhibits the Proliferation and Invasiveness of Glioma.

Huang G, Chen J, Liu J, Zhang X, Duan H, Fang Q
OncoTargets and therapy 2020;13:10817-10828

---

SNHG9 was upregulated in NSCLC and associated with DDP-resistance and poor prognosis of NSCLC patients.

Wang R, Chen C, Kang W, Meng G
American journal of translational research 2020;12(8):4456-4466

---

LncRNA RP11-395G23.3 suppresses the endometrial cancer progression via regulating microRNA-205-5p/PTEN axis.

Xin W, Gao X, Zhao S, Zhao P, Yu H, Wu Q, Hua K
American journal of translational research 2020;12(8):4422-4433

---

Brequinar inhibits enterovirus replication by targeting biosynthesis pathway of pyrimidines.

Fu H, Zhang Z, Dai Y, Liu S, Fu E
American journal of translational research 2020;12(12):8247-8255

---

A New Rat Model of Chronic Cerebral Hypoperfusion Resulting in Early-Stage Vascular Cognitive Impairment.

Wang J, Yang C, Wang H, Li D, Li T, Sun Y, Zhao M, Ma J, Hua W, Yang Z
Frontiers in aging neuroscience 2020;12:86

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Overexpression of IGFBP5 Enhances Radiosensitivity Through PI3K-AKT Pathway in Prostate Cancer.

Chen X, Yu Q, Pan H, Li P, Wang X, Fu S
Cancer management and research 2020;12:5409-5418

---

Long Noncoding RNA LINC00261 Reduces Proliferation and Migration of Breast Cancer Cells via the NME1-EMT Pathway.

Guo G, Dai S, Chen Q
Cancer management and research 2020;12:3081-3089

---

Resatorvid Relieves Breast Cancer Complicated with Depression by Inactivating Hippocampal Microglia Through TLR4/NF-κB/NLRP3 Signaling Pathway.

Luo W, Han Y, Meng P, Yang Q, Zhao H, Ling J, Wang Y
Cancer management and research 2020;12:13003-13014

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The lncRNA BCYRN1 Functions as an Oncogene in Human Glioma by Downregulating miR-125a-5p in vitro.

Yu W, Xiang D, Jia H, He X, Sheng J, Long Y, Zhu S, Wang K, Liu Q
Cancer management and research 2020;12:1151-1161

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Pyruvate dehydrogenase kinase 1 interferes with glucose metabolism reprogramming and mitochondrial quality control to aggravate stress damage in cancer.

Deng X, Wang Q, Cheng M, Chen Y, Yan X, Guo R, Sun L, Li Y, Liu Y
Journal of Cancer 2020;11(4):962-973

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Long Noncoding RNA DSCAM-AS1 Facilitates Colorectal Cancer Cell Proliferation and Migration via miR-137/Notch1 Axis.

Xu J, Wu G, Zhao Y, Han Y, Zhang S, Li C, Zhang J
Journal of Cancer 2020;11(22):6623-6632

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Arsenic trioxide (ATO) induced degradation of Cyclin D1 sensitized PD-1/PD-L1 checkpoint inhibitor in oral and esophageal squamous cell carcinoma.

Zhu G, Li X, Li J, Zhou W, Chen Z, Fan Y, Jiang Y, Zhao Y, Sun G, Mao W
Journal of Cancer 2020;11(22):6516-6529

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Translocator Protein 18 kDa (TSPO) Deficiency Inhibits Microglial Activation and Impairs Mitochondrial Function.

Yao R, Pan R, Shang C, Li X, Cheng J, Xu J, Li Y
Frontiers in pharmacology 2020;11:986

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Mitochondrial Iron Overload-Mediated Inhibition of Nrf2-HO-1/GPX4 Assisted ALI-Induced Nephrotoxicity.

Deng HF, Yue LX, Wang NN, Zhou YQ, Zhou W, Liu X, Ni YH, Huang CS, Qiu LZ, Liu H, Tan HL, Tang XL, Wang YG, Ma ZC, Gao Y
Frontiers in pharmacology 2020;11:624529

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Histone Deacetylase SIRT1 Mediates C5b-9-Induced Cell Cycle in Oligodendrocytes.

Tatomir A, Rao G, Boodhoo D, Vlaicu SI, Beltrand A, Anselmo F, Rus V, Rus H
Frontiers in immunology 2020;11:619

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Oleoylethanolamide Protects Against Acute Liver Injury by Regulating Nrf-2/HO-1 and NLRP3 Pathways in Mice.

Hu J, Zhu Z, Ying H, Yao J, Ma H, Li L, Zhao Y
Frontiers in pharmacology 2020;11:605065

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A Mechanism of Action Study on Danggui Sini Decoction to Discover Its Therapeutic Effect on Gastric Cancer.

Pan B, Wang Y, Wu C, Jia J, Huang C, Fang S, Liu L
Frontiers in pharmacology 2020;11:592903

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JAK2(V617F) Mutation Promoted IL-6 Production and Glycolysis via Mediating PKM1 Stabilization in Macrophages.

Li R, Sun N, Chen X, Li X, Zhao J, Cheng W, Hua H, Fukatsu M, Mori H, Takahashi H, Ohkawara H, Fukami M, Okamoto M, Hamazaki Y, Zheng K, Yang J, Ikezoe T
Frontiers in immunology 2020;11:589048

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Bu-Shen-Huo-Xue Decoction Ameliorates Diabetic Nephropathy by Inhibiting Rac1/PAK1/p38MAPK Signaling Pathway in High-Fat Diet/Streptozotocin-Induced Diabetic Mice.

Wang W, Long H, Huang W, Zhang T, Xie L, Chen C, Liu J, Xiong D, Hu W
Frontiers in pharmacology 2020;11:587663

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miR-222 Suppresses Immature Porcine Sertoli Cell Growth by Targeting the GRB10 Gene Through Inactivating the PI3K/AKT Signaling Pathway.

Luo H, Peng F, Weng B, Tang X, Chen Y, Yang A, Chen B, Ran M
Frontiers in genetics 2020;11:581593

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Bu-Yin-Qian-Zheng Formula Ameliorates MPP(+)-Induced Mitochondrial Dysfunction in Parkinson's Disease via Parkin.

Ma HJ, Gai C, Chai Y, Feng WD, Cheng CC, Zhang JK, Zhang YX, Yang LP, Guo ZY, Gao YS, Sun HM
Frontiers in pharmacology 2020;11:577017

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Molecular and Immune Characteristics for Lung Adenocarcinoma Patients With ERLIN2 Overexpression.

Liu Y, Xie P, Jiang D, Liu J, Zhang J, Bian T, Shi J
Frontiers in immunology 2020;11:568440

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microRNA-630 Regulates Underglycosylated IgA1 Production in the Tonsils by Targeting TLR4 in IgA Nephropathy.

Liu C, Ye MY, Yan WZ, Peng XF, He LY, Peng YM
Frontiers in immunology 2020;11:563699

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Metabolomics Deciphers Potential Targets of Xuefu Zhuyu Decoction Against Traumatic Brain Injury in Rat.

Li T, Hu E, Li P, Yang Z, Wu Y, Ding R, Zhu X, Tang T, Wang Y
Frontiers in pharmacology 2020;11:559618

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Susceptibility to Hyperglycemia in Rats With Stress-Induced Depressive-Like Behavior: Involvement of IL-6 Mediated Glucose Homeostasis Signaling.

Li X, Qiu W, Li N, Da X, Ma Q, Hou Y, Wang T, Song M, Chen J
Frontiers in psychiatry 2020;11:557

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PKM2-c-Myc-Survivin Cascade Regulates the Cell Proliferation, Migration, and Tamoxifen Resistance in Breast Cancer.

Yu P, Li AX, Chen XS, Tian M, Wang HY, Wang XL, Zhang Y, Wang KS, Cheng Y
Frontiers in pharmacology 2020;11:550469

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Effects of Xiaoyaosan on Depressive-Like Behaviors in Rats With Chronic Unpredictable Mild Stress Through HPA Axis Induced Astrocytic Activities.

Song M, Zhang J, Li X, Liu Y, Wang T, Yan Z, Chen J
Frontiers in psychiatry 2020;11:545823

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Lian Hua Qing Wen Capsules, a Potent Epithelial Protector in Acute Lung Injury Model, Block Proapoptotic Communication Between Macrophages, and Alveolar Epithelial Cells.

Li Q, Ran Q, Sun L, Yin J, Luo T, Liu L, Zhao Z, Yang Q, Li Y, Chen Y, Weng X, Wang Y, Cai W, Zhu X
Frontiers in pharmacology 2020;11:522729

---

ARP-1 Regulates the Transcriptional Activity of the Aromatase Gene in the Mouse Brain.

Honda SI, Harada N
Frontiers in endocrinology 2020;11:306

---

Scutellarein inhibits BLM-mediated pulmonary fibrosis by affecting fibroblast differentiation, proliferation, and apoptosis.

Miao K, Pan T, Mou Y, Zhang L, Xiong W, Xu Y, Yu J, Wang Y
Therapeutic advances in chronic disease 2020;11:2040622320940185

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MicroRNA-34a Inhibition Alleviates Lung Injury in Cecal Ligation and Puncture Induced Septic Mice.

Chen S, Ding R, Hu Z, Yin X, Xiao F, Zhang W, Yan S, Lv C
Frontiers in immunology 2020;11:1829

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PPARγ as an E3 Ubiquitin-Ligase Impedes Phosphate-Stat6 Stability and Promotes Prostaglandins E(2)-Mediated Inhibition of IgE Production in Asthma.

Wu J, Wang Y, Zhou Y, Wang Y, Sun X, Zhao Y, Guan Y, Zhang Y, Wang W
Frontiers in immunology 2020;11:1224

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Schisandrin B Inhibits Osteoclastogenesis and Protects Against Ovariectomy-Induced Bone Loss.

Wang J, Fang Z, Song C, Kang H, Guo Q, Dong Y, Zhang Y, Peng R, Guan H, Li F
Frontiers in pharmacology 2020;11:1175

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Toddalolactone Protects Lipopolysaccharide-Induced Sepsis and Attenuates Lipopolysaccharide-Induced Inflammatory Response by Modulating HMGB1-NF-κB Translocation.

Ni J, Zhao Y, Su J, Liu Z, Fang S, Li L, Deng J, Fan G
Frontiers in pharmacology 2020;11:109

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MiR-10a-5p-Mediated Syndecan 1 Suppression Restricts Porcine Hemagglutinating Encephalomyelitis Virus Replication.

Hu S, Li Z, Lan Y, Guan J, Zhao K, Chu D, Fan G, Guo Y, Gao F, He W
Frontiers in microbiology 2020;11:105

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Eye Drops of Metformin Prevents Fibrosis After Glaucoma Filtration Surgery in Rats via Activating AMPK/Nrf2 Signaling Pathway.

Li X, Leng Y, Jiang Q, Wang Z, Luo P, Zhang C, Chen L, Wang Y, Wang H, Yue X, Shen C, Zhou Y, Shi C, Xie L
Frontiers in pharmacology 2020;11:1038

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CoenzymeQ10-Induced Activation of AMPK-YAP-OPA1 Pathway Alleviates Atherosclerosis by Improving Mitochondrial Function, Inhibiting Oxidative Stress and Promoting Energy Metabolism.

Xie T, Wang C, Jin Y, Meng Q, Liu Q, Wu J, Sun H
Frontiers in pharmacology 2020;11:1034

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A miR-146a-5p/TRAF6/NF-kB p65 axis regulates pancreatic cancer chemoresistance: functional validation and clinical significance.

Meng Q, Liang C, Hua J, Zhang B, Liu J, Zhang Y, Wei M, Yu X, Xu J, Shi S
Theranostics 2020;10(9):3967-3979

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α1,6-Fucosyltransferase (FUT8) regulates the cancer-promoting capacity of cancer-associated fibroblasts (CAFs) by modifying EGFR core fucosylation (CF) in non-small cell lung cancer (NSCLC).

Li F, Zhao S, Cui Y, Guo T, Qiang J, Xie Q, Yu W, Guo W, Deng W, Gu C, Wu T
American journal of cancer research 2020;10(3):816-837

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Cardio-renal Exosomes in Myocardial Infarction Serum Regulate Proangiogenic Paracrine Signaling in Adipose Mesenchymal Stem Cells.

Gao L, Mei S, Zhang S, Qin Q, Li H, Liao Y, Fan H, Liu Z, Zhu H
Theranostics 2020;10(3):1060-1073

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Theta-burst transcranial magnetic stimulation promotes stroke recovery by vascular protection and neovascularization.

Zong X, Li Y, Liu C, Qi W, Han D, Tucker L, Dong Y, Hu S, Yan X, Zhang Q
Theranostics 2020;10(26):12090-12110

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Graphene oxide improves postoperative cognitive dysfunction by maximally alleviating amyloid beta burden in mice.

Zhang J, Zhu S, Jin P, Huang Y, Dai Q, Zhu Q, Wei P, Yang Z, Zhang L, Liu H, Xu G, Chen L, Gu E, Zhang Y, Wen L, Liu X
Theranostics 2020;10(26):11908-11920

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Targeting BCL10 by small peptides for the treatment of B cell lymphoma.

Bao W, Sun C, Sun X, He M, Yu H, Yan W, Wen F, Zhang L, Yang C
Theranostics 2020;10(25):11622-11636

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Flubendazole elicits anti-cancer effects via targeting EVA1A-modulated autophagy and apoptosis in Triple-negative Breast Cancer.

Zhen Y, Zhao R, Wang M, Jiang X, Gao F, Fu L, Zhang L, Zhou XL
Theranostics 2020;10(18):8080-8097

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Protein acetylation derepresses Serotonin Synthesis to potentiate Pancreatic Beta-Cell Function through HDAC1-PKA-Tph1 signaling.

Zhang Y, Wang S, Zhang L, Zhou F, Zhu K, Zhu Q, Liu Q, Liu Y, Jiang L, Ning G, Bi Y, Zhou L, Wang X
Theranostics 2020;10(16):7351-7368

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Homozygous MESP1 knock-in reporter hESCs facilitated cardiovascular cell differentiation and myocardial infarction repair.

Wang L, Zhang F, Duan F, Huang R, Chen X, Ming J, Na J
Theranostics 2020;10(15):6898-6914

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Extracellular vesicle-mediated delivery of miR-101 inhibits lung metastasis in osteosarcoma.

Zhang K, Dong C, Chen M, Yang T, Wang X, Gao Y, Wang L, Wen Y, Chen G, Wang X, Yu X, Zhang Y, Wang P, Shang M, Han K, Zhou Y
Theranostics 2020;10(1):411-425

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Aberrant miR-1246 expression promotes radioresistance in non-small cell lung cancer: a potential prognostic biomarker and radiotherapy sensitization target.

Fan L, Wang J, Cao Q, Ding X, Li B
American journal of cancer research 2020;10(1):314-335

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KLF13 suppresses the proliferation and growth of colorectal cancer cells through transcriptionally inhibiting HMGCS1-mediated cholesterol biosynthesis.

Yao W, Jiao Y, Zhou Y, Luo X
Cell & bioscience 2020;10:76

---

TIPE Regulates DcR3 Expression and Function by Activating the PI3K/AKT Signaling Pathway in CRC.

Zhong M, Qiu X, Liu Y, Yang Y, Gu L, Wang C, Chen H, Liu Z, Miao J, Zhuang G
Frontiers in oncology 2020;10:623048

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Forkhead Box Q1 Is Critical to Angiogenesis and Macrophage Recruitment of Colorectal Cancer.

Tang H, Zheng J, Bai X, Yue KL, Liang JH, Li DY, Wang LP, Wang JL, Guo Q
Frontiers in oncology 2020;10:564298

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Up-regulation of L Antigen Family Member 3 Associates With Aggressive Progression of Breast Cancer.

Dong X, Lv S, Gu D, Zhang X, Ye Z
Frontiers in oncology 2020;10:553628

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A Natural Dietary Flavone Myricetin as an α-Hemolysin Inhibitor for Controlling Staphylococcus aureus Infection.

Wang T, Zhang P, Lv H, Deng X, Wang J
Frontiers in cellular and infection microbiology 2020;10:330

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Steroid 5α-Reductase Type I Induces Cell Viability and Migration via Nuclear Factor-κB/Vascular Endothelial Growth Factor Signaling Pathway in Colorectal Cancer.

Wei R, Zhong S, Qiao L, Guo M, Shao M, Wang S, Jiang B, Yang Y, Gu C
Frontiers in oncology 2020;10:1501

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The SIRT6-Autophagy-Warburg Effect Axis in Papillary Thyroid Cancer.

Yang Z, Huang R, Wei X, Yu W, Min Z, Ye M
Frontiers in oncology 2020;10:1265

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Methylation-Induced Silencing of ALDH2 Facilitates Lung Adenocarcinoma Bone Metastasis by Activating the MAPK Pathway.

Yang M, Wang A, Li C, Sun J, Yi G, Cheng H, Liu X, Wang Z, Zhou Y, Yao G, Wang S, Liang R, Li B, Li D, Zhao H
Frontiers in oncology 2020;10:1141

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Prognostic and Clinicopathological Significance of X-Box-Binding Protein 1 and N-Acetyltransferase 1 in Gallbladder Cancer.

Liu R, Wu Z, Zhang Y, Miao X, Zou Q, Yuan Y, Li D, Yang Z
Frontiers in oncology 2020;10:1124

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NLRP6 contributes to inflammation and brain injury following intracerebral haemorrhage by activating autophagy.

Xiao H, Chen H, Jiang R, Zhang L, Wang L, Gan H, Jiang N, Zhao J, Zhai X, Liang P
Journal of molecular medicine (Berlin, Germany) 2020 Sep;98(9):1319-1331

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Low-dose naltrexone inhibits the epithelial-mesenchymal transition of cervical cancer cells in vitro and effects indirectly on tumor-associated macrophages in vivo.

Liu N, Ma M, Qu N, Wang R, Chen H, Hu F, Gao S, Shan F
International immunopharmacology 2020 Sep;86:106718

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Increased regulatory T cells and eosinophils characterize atopic dermatitis-like graft-versus-host disease compared with lichen planus-like graft-versus-host disease.

Li K, Mu Z, Wen G, Zhao Y, Cong X, Zhang J
Journal of the American Academy of Dermatology 2020 Sep;83(3):824-831

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Sublethal Levels of Antibiotics Promote Bacterial Persistence in Epithelial Cells.

Liu X, Liu F, Ding S, Shen J, Zhu K
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2020 Sep;7(18):1900840

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Mitochondrial Transplantation Attenuates Brain Dysfunction in Sepsis by Driving Microglial M2 Polarization.

Yan C, Ma Z, Ma H, Li Q, Zhai Q, Jiang T, Zhang Z, Wang Q
Molecular neurobiology 2020 Sep;57(9):3875-3890

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S-palmitoylation of swine interferon-inducible transmembrane protein is essential for its anti-JEV activity.

Xu Z, Li X, Xue J, Shen L, Zheng W, Yin S, Xu J
Virology 2020 Sep;548:82-92

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Deficiency of Grx1 leads to high sensitivity of HeLaS3 cells to oxidative stress via excessive accumulation of intracellular oxidants including ROS.

Zhao T, Zhang-Akiyama QM
Free radical research 2020 Sep;54(8-9):585-605

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Estrogen Exerts Neuroprotective Effects in Vascular Dementia Rats by Suppressing Autophagy and Activating the Wnt/β-Catenin Signaling Pathway.

Yang Y, Zhao L, Li N, Dai C, Yin N, Chu Z, Duan X, Niu X, Yan P, Lv P
Neurochemical research 2020 Sep;45(9):2100-2112

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MCC950 Inhibits NLRP3 Inflammasome and Alleviates Axonal Injures in Early Stages of Diffuse Axonal Injury in Rats.

Zhao J, Guo X, Wang B, Yang Z, Huang T, Guo D, Zhang M, Song J
Neurochemical research 2020 Sep;45(9):2020-2031

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A novel GNAS-mutated human induced pluripotent stem cell model for understanding GNAS-mutated tumors.

Watanabe K, Nakamura T, Onodera S, Saito A, Shibahara T, Azuma T
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2020 Sep;42(9):1010428320962588

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Visualization of translocator protein (18 kDa) (TSPO) in the retina of diabetic retinopathy rats using fluorine-18-DPA-714.

Zhou Y, Ou Y, Ju Z, Zhang X, Zheng L, Li J, Sun Y, Liu X
Annals of nuclear medicine 2020 Sep;34(9):675-681

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SRSF10 inhibits the polymerase activity and replication of avian influenza virus by regulating the alternative splicing of chicken ANP32A.

Fang A, Bi Z, Ye H, Yan L
Virus research 2020 Sep;286:198063

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The deubiquitylase USP2 maintains ErbB2 abundance via counteracting endocytic degradation and represents a therapeutic target in ErbB2-positive breast cancer.

Zhang J, Liu S, Li Q, Shi Y, Wu Y, Liu F, Wang S, Zaky MY, Yousuf W, Sun Q, Guo D, Wang T, Zhang Y, Wang Y, Li M, Liu H
Cell death and differentiation 2020 Sep;27(9):2710-2725

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RUNX3-dependent oxidative epithelial-to-mesenchymal transition in methamphetamine-induced chronic lung injury.

Shi L, Liu BY, Wang X, Zhu MJ, Chen L, Zhou MY, Gu YJ, Cheng L, Wang Y
Cell stress & chaperones 2020 Sep;25(5):793-802

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ACE2 modulates glucose homeostasis through GABA signaling during metabolic stress.

Ma X, Gao F, Chen Q, Xuan X, Wang Y, Deng H, Yang F, Yuan L
The Journal of endocrinology 2020 Sep;246(3):223-236

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Musashi2 promotes the progression of pancreatic cancer through a novel ISYNA1-p21/ZEB-1 pathway.

Zhou L, Sheng W, Jia C, Shi X, Cao R, Wang G, Lin Y, Zhu F, Dong Q, Dong M
Journal of cellular and molecular medicine 2020 Sep;24(18):10560-10572

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Tacrolimus ameliorates tubulointerstitial inflammation in diabetic nephropathy via inhibiting the NFATc1/TRPC6 pathway.

Zhang S, Wang H, Liu Y, Yang W, Liu J, Han Y, Liu Y, Liu F, Sun L, Xiao L
Journal of cellular and molecular medicine 2020 Sep;24(17):9810-9824

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Knockdown of endogenous RNF4 exacerbates ischaemia-induced cardiomyocyte apoptosis in mice.

Qiu F, Han Y, Shao X, Paulo P, Li W, Zhu M, Tang N, Guo S, Chen Y, Wu H, Zhao D, Liu Y, Chu W
Journal of cellular and molecular medicine 2020 Sep;24(17):9545-9559

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Rosamultin Attenuates Acute Hypobaric Hypoxia-Induced Bone Injuries by Regulation of Sclerostin and Its Downstream Signals.

Wang XM, Liu H, Li JY, Wei JX, Li X, Zhang YL, Li LZ, Zhang XZ
High altitude medicine & biology 2020 Sep;21(3):273-286

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Polyphyllin II inhibits human bladder cancer migration and invasion by regulating EMT-associated factors and MMPs.

Niu W, Xu L, Li J, Zhai Y, Sun Z, Shi W, Jiang Y, Ma C, Lin H, Guo Y, Liu Z
Oncology letters 2020 Sep;20(3):2928-2936

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Sirtuin 3-mediated deacetylation of acyl-CoA synthetase family member 3 by protocatechuic acid attenuates non-alcoholic fatty liver disease.

Sun R, Kang X, Zhao Y, Wang Z, Wang R, Fu R, Li Y, Hu Y, Wang Z, Shan W, Zhou J, Tian X, Yao J
British journal of pharmacology 2020 Sep;177(18):4166-4180

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Methamphetamine induces GSDME-dependent cell death in hippocampal neuronal cells through the endoplasmic reticulum stress pathway.

Liu Y, Wen D, Gao J, Xie B, Yu H, Shen Q, Zhang J, Jing W, Cong B, Ma C
Brain research bulletin 2020 Sep;162:73-83

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Inhibition of NK1R attenuates LPS-induced microglial inflammation and consequent death of PC12 cells.

Jiang W, Wang X, Wang W, Hua F, Zhang Z, Zhang Z, Xiang J, Yang X
Brain research bulletin 2020 Sep;162:115-124

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NS5-V372A and NS5-H386Y variations are responsible for differences in interferon α/β induction and co-contribute to the replication advantage of Japanese encephalitis virus genotype I over genotype III in ducklings.

Li C, Di D, Huang H, Wang X, Xia Q, Ma X, Liu K, Li B, Shao D, Qiu Y, Li Z, Wei J, Ma Z
PLoS pathogens 2020 Sep;16(9):e1008773

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H63D variant of the homeostatic iron regulator (HFE) gene alters α-synuclein expression, aggregation, and toxicity.

Kim Y, Stahl MC, Huang X, Connor JR
Journal of neurochemistry 2020 Sep;155(2):177-190

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Interleukin-18 levels in the hippocampus and behavior of adult rat offspring exposed to prenatal restraint stress during early and late pregnancy.

Chen MX, Liu Q, Cheng S, Lei L, Lin AJ, Wei R, K Hui TC, Li Q, Ao LJ, Sham PC
Neural regeneration research 2020 Sep;15(9):1748-1756

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Control the fate of human umbilical cord mesenchymal stem cells with dual-enzymatically cross-linked gelatin hydrogels for potential applications in nerve regeneration.

Li J, Gao F, Ma S, Zhang Y, Zhang J, Guan F, Yao M
Journal of tissue engineering and regenerative medicine 2020 Sep;14(9):1261-1271

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Duck IFIT5 differentially regulates Tembusu virus replication and inhibits virus-triggered innate immune response.

Wu X, Liu K, Jia R, Pan Y, Wang M, Chen S, Liu M, Zhu D, Zhao X, Wu Y, Yang Q, Zhang S, Huang J, Zhang L, Liu Y, Tian B, Pan L, Yu Y, Ur Rehman M, Yin Z, Jing B, Cheng A
Cytokine 2020 Sep;133:155161

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The effect of monotropein on alleviating cisplatin-induced acute kidney injury by inhibiting oxidative damage, inflammation and apoptosis.

Zhang Y, Chen Y, Li B, Ding P, Jin D, Hou S, Cai X, Sheng X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110408

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Dual PI3K/mTOR inhibitor PKI-402 suppresses the growth of ovarian cancer cells by degradation of Mcl-1 through autophagy.

Hu X, Xia M, Wang J, Yu H, Chai J, Zhang Z, Sun Y, Su J, Sun L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110397

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SOCS3-deficient lung epithelial cells uptaking neutrophil-derived SOCS3 worsens lung influenza infection.

Li L, Wu H, Li Q, Chen J, Xu K, Xu J, Su X
Molecular immunology 2020 Sep;125:51-62

---

The roles of grouper TANK in innate immune defense against iridovirus and nodavirus infections.

Wei J, Li C, Ou J, Zhang X, Liu Z, Qin Q
Fish & shellfish immunology 2020 Sep;104:506-516

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Zinc exerts its renal protection effect on arsenic-exposed common carp: A signaling network comprising Nrf2, NF-κB and MAPK pathways.

Wang Y, Zhao H, Liu Y, Nie X, Xing M
Fish & shellfish immunology 2020 Sep;104:383-390

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S-allyl-L-cysteine protects hepatocytes from indomethacin-induced apoptosis by attenuating endoplasmic reticulum stress.

Chen P, Chen C, Hu M, Cui R, Liu F, Yu H, Ren Y
FEBS open bio 2020 Sep;10(9):1900-1911

---

HEATR1 promotes proliferation in gastric cancer in vitro and in vivo.

Zhao J, Zhu Y, Fu Q, Zhu Y, Zhao G
Acta biochimica et biophysica Sinica 2020 Sep 8;52(9):1030-1039

---

Autocrine INSL5 promotes tumor progression and glycolysis via activation of STAT5 signaling.

Li SB, Liu YY, Yuan L, Ji MF, Zhang A, Li HY, Tang LQ, Fang SG, Zhang H, Xing S, Li MZ, Zhong Q, Lin SJ, Liu WL, Huang P, Zeng YX, Zheng YM, Ling ZQ, Sui JH, Zeng MS
EMBO molecular medicine 2020 Sep 7;12(9):e12050

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Circular RNA circREPS2 Acts as a Sponge of miR-558 to Suppress Gastric Cancer Progression by Regulating RUNX3/β-catenin Signaling.

Guo X, Dai X, Liu J, Cheng A, Qin C, Wang Z
Molecular therapy. Nucleic acids 2020 Sep 4;21:577-591

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The microRNA/TET3/REST axis is required for olfactory globose basal cell proliferation and male behavior.

Yang D, Wu X, Zhou Y, Wang W, Wang Z
EMBO reports 2020 Sep 3;21(9):e49431

---

Oxidative stress mediates the apoptosis and epigenetic modification of the Bcl-2 promoter via DNMT1 in a cigarette smoke-induced emphysema model.

Zeng H, Li T, He X, Cai S, Luo H, Chen P, Chen Y
Respiratory research 2020 Sep 3;21(1):229

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Myricanol 5-fluorobenzyloxy ether regulation of survivin pathway inhibits human lung adenocarcinoma A549 cells growth in vitro.

Dai GH, Chen X, Ren ZM, Dai CJ, Tong YL, Chai KQ
BMC complementary medicine and therapies 2020 Sep 3;20(1):269

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Characterization of Low Molecular Weight Sulfate Ulva Polysaccharide and its Protective Effect against IBD in Mice.

Li Y, Ye H, Wang T, Wang P, Liu R, Li Y, Tian Y, Zhang J
Marine drugs 2020 Sep 29;18(10)

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NOD2/c-Jun NH(2)-Terminal Kinase Triggers Mycoplasma ovipneumoniae-Induced Macrophage Autophagy.

Luo H, Wu X, Xu Z, Hao X, Wang Y, Li M
Journal of bacteriology 2020 Sep 23;202(20)

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L-Theanine affects intestinal mucosal immunity by regulating short-chain fatty acid metabolism under dietary fiber feeding.

Xu W, Lin L, Liu A, Zhang T, Zhang S, Li Y, Chen J, Gong Z, Liu Z, Xiao W
Food & function 2020 Sep 23;11(9):8369-8379

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Astaxanthin attenuates oxidative stress and immune impairment in D-galactose-induced aging in rats by activating the Nrf2/Keap1 pathway and suppressing the NF-κB pathway.

Chen Z, Xiao J, Liu H, Yao K, Hou X, Cao Y, Liu X
Food & function 2020 Sep 23;11(9):8099-8111

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Neural progenitor cell pyroptosis contributes to Zika virus-induced brain atrophy and represents a therapeutic target.

He Z, An S, Chen J, Zhang S, Tan C, Yu J, Ye H, Wu Y, Yuan J, Wu J, Zhu X, Li M
Proceedings of the National Academy of Sciences of the United States of America 2020 Sep 22;117(38):23869-23878

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(+)-Clausenamide protects against drug-induced liver injury by inhibiting hepatocyte ferroptosis.

Wang M, Liu CY, Wang T, Yu HM, Ouyang SH, Wu YP, Gong HB, Ma XH, Jiao GL, Fu LL, Wu QS, Kurihara H, Li YF, Shen T, He RR
Cell death & disease 2020 Sep 19;11(9):781

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Overexpression of MicroRNA-9a-5p Ameliorates NLRP1 Inflammasome-mediated Ischemic Injury in Rats Following Ischemic Stroke.

Cao Y, Zhang H, Lu X, Wang J, Zhang X, Sun S, Bao Z, Tian W, Ning S, Wang L, Cui L
Neuroscience 2020 Sep 15;444:106-117

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Inhibition of autophagy enhances timosaponin AIII-induced lung cancer cell apoptosis and anti-tumor effect in vitro and in vivo.

Liu J, Deng X, Sun X, Dong J, Huang J
Life sciences 2020 Sep 15;257:118040

---

Inflammasome/NF-κB translocation inhibition via PPARγ agonist mitigates inorganic mercury induced nephrotoxicity.

Li S, Shi M, Wan Y, Wang Y, Zhu M, Wang B, Zhan Y, Ran B, Wu C
Ecotoxicology and environmental safety 2020 Sep 15;201:110801

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FUT9-Driven Programming of Colon Cancer Cells towards a Stem Cell-Like State.

Blanas A, Zaal A, van der Haar Àvila I, Kempers M, Kruijssen L, de Kok M, Popovic MA, van der Horst JC, J van Vliet S
Cancers 2020 Sep 10;12(9)

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Adenovirus-mediated specific tumor tagging facilitates CAR-T therapy against antigen-mismatched solid tumors.

Tang X, Li Y, Ma J, Wang X, Zhao W, Hossain MA, Yang Y
Cancer letters 2020 Sep 1;487:1-9

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The AKT/GSK3-Mediated Slug Expression Contributes to Oxaliplatin Resistance in Colorectal Cancer via Upregulation of ERCC1.

Wei W, Ma XD, Jiang GM, Shi B, Zhong W, Sun CL, Zhao L, Hou YJ, Wang H
Oncology research 2020 Sep 1;28(4):423-438

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Combination of luteolin and lycopene effectively protect against the "two-hit" in NAFLD through Sirt1/AMPK signal pathway.

Zhu Y, Liu R, Shen Z, Cai G
Life sciences 2020 Sep 1;256:117990

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Four active monomers from Moutan Cortex exert inhibitory effects against oxidative stress by activating Nrf2/Keap1 signaling pathway.

Zhang B, Yu D, Luo N, Yang C, Zhu Y
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2020 Sep 1;24(5):373-384

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Herpes Simplex Virus Type 2 Inhibits Type I IFN Signaling Mediated by the Novel E3 Ubiquitin Protein Ligase Activity of Viral Protein ICP22.

Zhang M, Fu M, Li M, Hu H, Gong S, Hu Q
Journal of immunology (Baltimore, Md. : 1950) 2020 Sep 1;205(5):1281-1292

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Targeting SLC7A11 specifically suppresses the progression of colorectal cancer stem cells via inducing ferroptosis.

Xu X, Zhang X, Wei C, Zheng D, Lu X, Yang Y, Luo A, Zhang K, Duan X, Wang Y
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2020 Sep 1;152:105450

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Stimulation of endothelial progenitor cells by microRNA-31a-5p to induce endothelialization in an aneurysm neck after coil embolization by modulating the Axin1-mediated β-catenin/vascular endothelial growth factor pathway.

Yu G, Liu P, Shi Y, Li S, Liu Y, Fan Z, Zhu W
Journal of neurosurgery 2020 Sep 1;133(3):918-926

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Expression Level of Small Envelope Protein in Addition to Sequence Divergence inside Its Major Hydrophilic Region Contributes to More Efficient Surface Antigen Secretion by Hepatitis B Virus Subgenotype D2 than Subgenotype A2.

Wang Q, Fu S, Zhang J, Yuan Q, Li J, Xia N, Wen YM, Wang Y, Tong S
Viruses 2020 Sep 1;12(9)

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Down-regulation of NTSR3 inhibits cell growth and metastasis, as well as the PI3K-AKT and MAPK signaling pathways in colorectal cancer.

Liu A, Zuo Z, Liu L, Liu L
Biochemistry and cell biology = Biochimie et biologie cellulaire 2020 Oct;98(5):548-555

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Cytotoxic effects of vitamins K1, K2, and K3 against human T lymphoblastoid leukemia cells through apoptosis induction and cell cycle arrest.

Xu W, Wu H, Chen S, Wang X, Tanaka S, Sugiyama K, Yamada H, Hirano T
Chemical biology & drug design 2020 Oct;96(4):1134-1147

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Ubiquitin specific protease 5 negatively regulates the IFNs-mediated antiviral activity via targeting SMURF1.

Qian G, Zhu L, Huang C, Liu Y, Ren Y, Ding Y, Qian W, Xu Q, Zheng H, Lv H
International immunopharmacology 2020 Oct;87:106763

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Lycopene protects neuroblastoma cells against oxidative damage via depression of ER stress.

Ou S, Fang Y, Tang H, Wu T, Chen L, Jiang M, Zhou L, Xu J, Guo K
Journal of food science 2020 Oct;85(10):3552-3561

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Upregulation of secreted phosphoprotein 1 affects malignant progression, prognosis, and resistance to cetuximab via the KRAS/MEK pathway in head and neck cancer.

Liu K, Hu H, Jiang H, Liu C, Zhang H, Gong S, Wei D, Yu Z
Molecular carcinogenesis 2020 Oct;59(10):1147-1158

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Resveratrol modulates the apoptosis and autophagic death of human lung adenocarcinoma A549 cells via a p53‑dependent pathway: Integrated bioinformatics analysis and experimental validation.

Fan Y, Li J, Yang Y, Zhao X, Liu Y, Jiang Y, Zhou L, Feng Y, Yu Y, Cheng Y
International journal of oncology 2020 Oct;57(4):925-938

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Schisandrin A restrains osteoclastogenesis by inhibiting reactive oxygen species and activating Nrf2 signalling.

Ni S, Qian Z, Yuan Y, Li D, Zhong Z, Ghorbani F, Zhang X, Zhang F, Zhang Z, Liu Z, Yu B
Cell proliferation 2020 Oct;53(10):e12882

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YY1-mediated PTEN dephosphorylation antagonizes IR-induced DNA repair contributing to tongue squamous cell carcinoma radiosensitization.

Zhao L, Li R, Qiu JZ, Yu JB, Cao Y, Yuan RT
Molecular and cellular probes 2020 Oct;53:101577

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Spatiotemporal expression of neurogenic locus notch homolog protein 1 in developing caudal spinal cord of fetuses with anorectal malformations from ETU-fed rats.

Yang Z, Jia H, Bai Y, Wang W
Journal of molecular histology 2020 Oct;51(5):519-530

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Silica nanoparticles induce spermatogenesis disorders via L3MBTL2-DNA damage-p53 apoptosis and RNF8-ubH2A/ubH2B pathway in mice.

Liu J, Li X, Zhou G, Sang Y, Zhang Y, Zhao Y, Ge W, Sun Z, Zhou X
Environmental pollution (Barking, Essex : 1987) 2020 Oct;265(Pt A):114974

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Autophagy plays a protective role during Pseudomonas aeruginosa-induced apoptosis via ROS-MAPK pathway.

Han L, Ma Q, Yu J, Gong Z, Ma C, Xu Y, Deng G, Wu X
Innate immunity 2020 Oct;26(7):580-591

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LKB1-MARK2 signalling mediates lipopolysaccharide-induced production of cytokines in mouse macrophages.

Deng J, Wen C, Ding X, Zhang X, Hou G, Liu A, Xu H, Cao X, Bai Y
Journal of cellular and molecular medicine 2020 Oct;24(19):11307-11317

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Dihydrotanshinone I inhibits ovarian cancer cell proliferation and migration by transcriptional repression of PIK3CA gene.

Wang X, Xu X, Jiang G, Zhang C, Liu L, Kang J, Wang J, Owusu L, Zhou L, Zhang L, Li W
Journal of cellular and molecular medicine 2020 Oct;24(19):11177-11187

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KIAA1429 regulates cell proliferation by targeting c-Jun messenger RNA directly in gastric cancer.

Miao R, Dai CC, Mei L, Xu J, Sun SW, Xing YL, Wu LS, Wang MH, Wei JF
Journal of cellular physiology 2020 Oct;235(10):7420-7432

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Silencing long non‑coding RNA NEAT1 suppresses the tumorigenesis of infantile hemangioma by competitively binding miR‑33a‑5p to stimulate HIF1α/NF‑κB pathway.

Yu L, Shu H, Xing L, Lv MX, Li L, Xie YC, Zhang Z, Zhang L, Xie YY
Molecular medicine reports 2020 Oct;22(4):3358-3366

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Arsenic (III) and/or copper (II) induces oxidative stress in chicken brain and subsequent effects on mitochondrial homeostasis and autophagy.

Liu Y, Zhao H, Wang Y, Guo M, Mu M, Xing M
Journal of inorganic biochemistry 2020 Oct;211:111201

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Dihydrotanshinone I inhibits human glioma cell proliferation via the activation of ferroptosis.

Tan S, Hou X, Mei L
Oncology letters 2020 Oct;20(4):122

---

Essential roles of S100A10 in Toll-like receptor signaling and immunity to infection.

Lou Y, Han M, Liu H, Niu Y, Liang Y, Guo J, Zhang W, Wang H
Cellular & molecular immunology 2020 Oct;17(10):1053-1062

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miR-103a-3p regulates mitophagy in Parkinson's disease through Parkin/Ambra1 signaling.

Zhou J, Zhao Y, Li Z, Zhu M, Wang Z, Li Y, Xu T, Feng D, Zhang S, Tang F, Yao J
Pharmacological research 2020 Oct;160:105197

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p53 promotes ZDHHC1-mediated IFITM3 palmitoylation to inhibit Japanese encephalitis virus replication.

Wang X, Wu Z, Li Y, Yang Y, Xiao C, Liu X, Xiang X, Wei J, Shao D, Liu K, Deng X, Wu J, Qiu Y, Li B, Ma Z
PLoS pathogens 2020 Oct;16(10):e1009035

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A Histomorphological Study of the Divergent Corpus Spongiosum Surrounding the Urethral Plate in Hypospadias.

Bao X, Huang Y, Lyu Y, Xi Z, Xie H, Fu Q, Song L, Chen F
Urology 2020 Oct;144:188-193

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Exosomal miR-1255b-5p targets human telomerase reverse transcriptase in colorectal cancer cells to suppress epithelial-to-mesenchymal transition.

Zhang X, Bai J, Yin H, Long L, Zheng Z, Wang Q, Chen F, Yu X, Zhou Y
Molecular oncology 2020 Oct;14(10):2589-2608

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Polydatin alleviates parkinsonism in MPTP-model mice by enhancing glycolysis in dopaminergic neurons.

Zhang S, Wang S, Shi X, Feng X
Neurochemistry international 2020 Oct;139:104815

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Proteomic analyses reveal that Orf virus induces the activation and maturation of mouse bone marrow-derived dendritic cells.

Feng Q, Li L, Du G, Liu Y, Liu X, Wu J, Shang Y
Research in veterinary science 2020 Oct;132:563-573

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Biomechanically reduced expression of Derlin-3 is linked to the apoptosis of chondrocytes in the mandibular condylar cartilage via the endoplasmic reticulum stress pathway.

Liu J, Yang H, Zhang H, Liu Q, Zhou P, He F, Zhang M, Yu S, Liu J, Wang M
Archives of oral biology 2020 Oct;118:104843

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T-type calcium channel blockade induces apoptosis in C2C12 myotubes and skeletal muscle via endoplasmic reticulum stress activation.

Chen M, Li S, Hao M, Chen J, Zhao Z, Hong S, Min J, Tang J, Hu M, Hong L
FEBS open bio 2020 Oct;10(10):2122-2136

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Impaired NLRP3 inflammasome activation/pyroptosis leads to robust inflammatory cell death via caspase-8/RIPK3 during coronavirus infection.

Zheng M, Williams EP, Malireddi RKS, Karki R, Banoth B, Burton A, Webby R, Channappanavar R, Jonsson CB, Kanneganti TD
The Journal of biological chemistry 2020 Oct 9;295(41):14040-14052

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Calreticulin promotes EMT in pancreatic cancer via mediating Ca(2+) dependent acute and chronic endoplasmic reticulum stress.

Sheng W, Wang G, Tang J, Shi X, Cao R, Sun J, Lin YH, Jia C, Chen C, Zhou J, Dong M
Journal of experimental & clinical cancer research : CR 2020 Oct 7;39(1):209

---

Profiling pro-neural to mesenchymal transition identifies a lncRNA signature in glioma.

Liang Q, Guan G, Li X, Wei C, Wu J, Cheng P, Wu A, Cheng W
Journal of translational medicine 2020 Oct 7;18(1):378

---

Revealing active ingredients, potential targets, and action mechanism of Ermiao fang for treating endometritis based on network pharmacology strategy.

Zhang C, Su T, Yu D, Wang F, Yue C, Wang HQ
Journal of ethnopharmacology 2020 Oct 5;260:113051

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c-Myc inactivation of p53 through the pan-cancer lncRNA MILIP drives cancer pathogenesis.

Feng YC, Liu XY, Teng L, Ji Q, Wu Y, Li JM, Gao W, Zhang YY, La T, Tabatabaee H, Yan XG, Jamaluddin MFB, Zhang D, Guo ST, Scott RJ, Liu T, Thorne RF, Zhang XD, Jin L
Nature communications 2020 Oct 5;11(1):4980

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Defect of SLC38A3 promotes epithelial-mesenchymal transition and predicts poor prognosis in esophageal squamous cell carcinoma.

Liu R, Hong R, Wang Y, Gong Y, Yeerken D, Yang D, Li J, Fan J, Chen J, Zhang W, Zhan Q
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2020 Oct 31;32(5):547-563

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Transcriptomic and Proteomic Analysis Reveals Mechanisms of Patulin-Induced Cell Toxicity in Human Embryonic Kidney Cells.

Han N, Luo R, Liu J, Guo T, Feng J, Peng X
Toxins 2020 Oct 29;12(11)

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Anticancer Effects of Honokiol via Mitochondrial Dysfunction Are Strongly Enhanced by the Mitochondria-Targeting Carrier Berberine.

Shi X, Zhang T, Lou H, Song H, Li C, Fan P
Journal of medicinal chemistry 2020 Oct 22;63(20):11786-11800

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Rosmarinic Acid Alleviates Inflammation, Apoptosis, and Oxidative Stress through Regulating miR-155-5p in a Mice Model of Parkinson's Disease.

Lv R, Du L, Zhou F, Yuan X, Liu X, Zhang L
ACS chemical neuroscience 2020 Oct 21;11(20):3259-3266

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miR-497 regulates fatty acid synthesis via LATS2 in bovine mammary epithelial cells.

Chen Z, Chu S, Liang Y, Xu T, Sun Y, Li M, Zhang H, Wang X, Mao Y, Loor JJ, Wu Y, Yang Z
Food & function 2020 Oct 21;11(10):8625-8636

---

Amorphous silica nanoparticles accelerated atherosclerotic lesion progression in ApoE(-/-) mice through endoplasmic reticulum stress-mediated CD36 up-regulation in macrophage.

Ma R, Qi Y, Zhao X, Li X, Sun X, Niu P, Li Y, Guo C, Chen R, Sun Z
Particle and fibre toxicology 2020 Oct 2;17(1):50

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Sodium butyrate promotes milk fat synthesis in bovine mammary epithelial cells via GPR41 and its downstream signalling pathways.

Cheng J, Zhang Y, Ge Y, Li W, Cao Y, Qu Y, Liu S, Guo Y, Fu S, Liu J
Life sciences 2020 Oct 15;259:118375

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Designing an eEF2K-Targeting PROTAC small molecule that induces apoptosis in MDA-MB-231 cells.

Liu Y, Zhen Y, Wang G, Yang G, Fu L, Liu B, Ouyang L
European journal of medicinal chemistry 2020 Oct 15;204:112505

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Sestrin2 promotes angiogenesis to alleviate brain injury by activating Nrf2 through regulating the interaction between p62 and Keap1 following photothrombotic stroke in rats.

Li Y, Wu J, Yu S, Zhu J, Zhou Y, Wang P, Li L, Zhao Y
Brain research 2020 Oct 15;1745:146948

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Upregulation of Glutaredoxin 2 alleviates oxygen-glucose deprivation/reoxygenation-induced apoptosis and ROS production in neurons by enhancing Nrf2 signaling via modulation of GSK-3β.

Wen J, Li X, Zheng S, Xiao Y
Brain research 2020 Oct 15;1745:146946

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A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters.

Wang Y, Zhu Y, Niu J, Deng Q, Guo S, Jiang H, Peng Z, Xue Y, Peng H, Xuan L, Pan G
Toxicology and applied pharmacology 2020 Oct 1;404:115169

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Polydatin executes anticancer effects against glioblastoma multiforme by inhibiting the EGFR-AKT/ERK1/2/STAT3-SOX2/Snail signaling pathway.

Chen Y, Niu J, Li L, Li Z, Jiang J, Zhu M, Dong T, Zhang J, Shi C, Xu P, Lu Y, Jiang Y, Liu P, Chen W
Life sciences 2020 Oct 1;258:118158

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Notch1 contributes to TNF-α-induced proliferation and migration of airway smooth muscle cells through regulation of the Hes1/PTEN axis.

Li X, Zou F, Lu Y, Fan X, Wu Y, Feng X, Sun X, Liu Y
International immunopharmacology 2020 Nov;88:106911

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Knockdown of fatty acid binding protein 4 exacerbates Bacillus Calmette-Guerin infection-induced RAW264.7 cell apoptosis via the endoplasmic reticulum stress pathway.

Yu J, Ma C, Xu Y, Han L, Wu X, Wang Y, Deng G
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2020 Nov;85:104552

---

Enhanced therapeutic efficacy of a novel colon-specific nanosystem loading emodin on DSS-induced experimental colitis.

Wang D, Sun M, Zhang Y, Chen Z, Zang S, Li G, Li G, Clark AR, Huang J, Si L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Nov;78:153293

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CaMKII as a key regulator of contrast-induced nephropathy through mPTP opening in HK-2 cells.

Hu C, Zhou G, Liu K, Yin W, Zhou L, Wang J, Chen L, Zuo S, Xie Y, Zuo X
Cellular signalling 2020 Nov;75:109734

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Histone demethylase Jmjd3 modulates osteoblast apoptosis induced by tumor necrosis factor-alpha through directly targeting RASSF5.

Sun HY, Yang D, Mi J, Yu YQ, Qiu LH
Connective tissue research 2020 Nov;61(6):517-525

---

RNA binding motif protein 10 suppresses lung cancer progression by controlling alternative splicing of eukaryotic translation initiation factor 4H.

Zhang S, Bao Y, Shen X, Pan Y, Sun Y, Xiao M, Chen K, Wei H, Zuo J, Saffen D, Zong WX, Sun Y, Wang Z, Wang Y
EBioMedicine 2020 Nov;61:103067

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Spatiotemporal heterogeneity of PPARγ expression in porcine uteroplacenta for regulating of placental angiogenesis through VEGF-mediated signalling.

Zhang J, Xue L, Nie A, Yang Q, Peng X, Chen Z, Yang L, Xie Y, Yuan A, Xu J
Reproduction in domestic animals = Zuchthygiene 2020 Nov;55(11):1479-1489

---

Identification of octopus peptide and its promotion of β-casein synthesis in a mouse mammary epithelial cell line.

Cai B, Wan P, Chen H, Chen X, Sun H, Pan J
Journal of food biochemistry 2020 Nov;44(11):e13467

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Low-intensity pulsed ultrasound protects subchondral bone in rabbit temporomandibular joint osteoarthritis by suppressing TGF-β1/Smad3 pathway.

Yi X, Wu L, Liu J, Qin YX, Li B, Zhou Q
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2020 Nov;38(11):2505-2512

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Involvement of NMDAR/PSD-95/nNOS-NO-cGMP pathway in embryonic exposure to BPA induced learning and memory dysfunction of rats.

Yu H, Ma L, Liu D, Wang Y, Pei X, Duan Z, Ma M, Zhang Y
Environmental pollution (Barking, Essex : 1987) 2020 Nov;266(Pt 1):115055

---

Long noncoding RNA LINC00346 promotes glioma cell migration, invasion and proliferation by up-regulating ROCK1.

Chen X, Li D, Chen L, Hao B, Gao Y, Li L, Zhou C, He X, Cao Y
Journal of cellular and molecular medicine 2020 Nov;24(22):13010-13019

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MicroRNA-127-5p impairs function of granulosa cells via HMGB2 gene in premature ovarian insufficiency.

Zhang X, Dang Y, Liu R, Zhao S, Ma J, Qin Y
Journal of cellular physiology 2020 Nov;235(11):8826-8838

---

Oxidative stress is important in the pathogenesis of stress-related mucosal disease.

Wang X, Zhao Q, Shi H, Qi F, Shi N, Bai D, Li X, Yuan H, Zuo X
Experimental and therapeutic medicine 2020 Nov;20(5):83

---

Brilliant blue G attenuates neuro-inflammation via regulating MAPKs and NF-κB signaling pathways in lipopolysaccharide-induced BV2 microglia cells.

Wang W, Huang F, Jiang W, Wang W, Xiang J
Experimental and therapeutic medicine 2020 Nov;20(5):116

---

Methylprednisolone potentiates tetrandrine pharmacodynamics against human T lymphoblastoid leukemia MOLT-4 cells via regulation of NF-κB activation and cell cycle transition.

Xu W, Chen S, Wang X, Wu H, Yamada H, Hirano T
Steroids 2020 Nov;163:108714

---

Activation of angiotensin II type-2 receptor protects against cigarette smoke-induced COPD.

Mei D, Tan WSD, Liao W, Heng CKM, Wong WSF
Pharmacological research 2020 Nov;161:105223

---

Up-regulation of astrocyte excitatory amino acid transporter 2 alleviates central sensitization in a rat model of chronic migraine.

Zhou X, Liang J, Wang J, Fei Z, Qin G, Zhang D, Zhou J, Chen L
Journal of neurochemistry 2020 Nov;155(4):370-389

---

TRIM25 upregulation by Mycobacterium tuberculosis infection promotes intracellular survival of M.tb in RAW264.7 cells.

Liu H, Zhu T, Li Q, Xiong X, Wang J, Zhu X, Zhou X, Zhang L, Zhu Y, Peng Y, Chen Y, Hu C, Chen H, Guo A
Microbial pathogenesis 2020 Nov;148:104456

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Indirubin alleviates bleomycin-induced pulmonary fibrosis in mice by suppressing fibroblast to myofibroblast differentiation.

Wang Q, Yu J, Hu Y, Chen X, Zhang L, Pan T, Miao K, Mou Y, Xu Y, Xiong W, Wang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110715

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Nucleoredoxin interaction with flightless-I/actin complex is differentially altered in alcoholic liver disease.

Alarcón-Sánchez BR, Guerrero-Escalera D, Rosas-Madrigal S, Ivette Aparicio-Bautista D, Reyes-Gordillo K, Lakshman MR, Ortiz-Fernández A, Quezada H, Medina-Contreras Ó, Villa-Treviño S, Isael Pérez-Carreón J, Arellanes-Robledo J
Basic & clinical pharmacology & toxicology 2020 Nov;127(5):389-404

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Mycoplasma bovis-generated reactive oxygen species and induced apoptosis in bovine mammary epithelial cell cultures.

Liu Y, Zhou M, Xu S, Khan MA, Shi Y, Qu W, Gao J, Liu G, Kastelic JP, Han B
Journal of dairy science 2020 Nov;103(11):10429-10445

---

Sox13 promotes hepatocellular carcinoma metastasis by transcriptionally activating Twist1.

Feng M, Fang F, Fang T, Jiao H, You S, Wang X, Zhao W
Laboratory investigation; a journal of technical methods and pathology 2020 Nov;100(11):1400-1410

---

TMEM176A acts as a tumor suppressor gene in pancreatic cancer by inhibiting ERK signaling.

Guo Y, Cao F, Hu S, Liu S, Sun H, Li A, Li F
Discovery medicine 2020 Nov-Dec;30(161):145-153

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Deficiency of microglial Hv1 channel is associated with activation of autophagic pathway and ROS production in LPC-induced demyelination mouse model.

Chen M, Yang LL, Hu ZW, Qin C, Zhou LQ, Duan YL, Bosco DB, Wu LJ, Zhan KB, Xu SB, Tian DS
Journal of neuroinflammation 2020 Nov 6;17(1):333

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Effects of Osthole on Progesterone Secretion in Chicken Preovulatory Follicles Granulosa Cells.

Sun N, Zhang Y, Hou Y, Yi Y, Guo J, Zheng X, Sun P, Sun Y, Khan A, Li H
Animals : an open access journal from MDPI 2020 Nov 4;10(11)

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Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation.

Quan L, Ohgaki R, Hara S, Okuda S, Wei L, Okanishi H, Nagamori S, Endou H, Kanai Y
Journal of experimental & clinical cancer research : CR 2020 Nov 30;39(1):266

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Anthocyanins decrease the internalization of TiO(2) nanoparticles into 3D Caco-2 spheroids.

Wang J, Zhang J, Li S, Huang C, Xie Y, Cao Y
Food chemistry 2020 Nov 30;331:127360

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Hypoxia induces sorafenib resistance mediated by autophagy via activating FOXO3a in hepatocellular carcinoma.

Liang C, Dong Z, Cai X, Shen J, Xu Y, Zhang M, Li H, Yu W, Chen W
Cell death & disease 2020 Nov 29;11(11):1017

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Effective RNA Knockdown Using CRISPR-Cas13a and Molecular Targeting of the EML4-ALK Transcript in H3122 Lung Cancer Cells.

Saifullah, Sakari M, Suzuki T, Yano S, Tsukahara T
International journal of molecular sciences 2020 Nov 24;21(23)

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MiR-103a-3p promotes tumour glycolysis in colorectal cancer via hippo/YAP1/HIF1A axis.

Sun Z, Zhang Q, Yuan W, Li X, Chen C, Guo Y, Shao B, Dang Q, Zhou Q, Wang Q, Wang G, Liu J, Kan Q
Journal of experimental & clinical cancer research : CR 2020 Nov 20;39(1):250

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Velvet antler polypeptide prevents the disruption of hepatic tight junctions via inhibiting oxidative stress in cholestatic mice and liver cell lines.

Li L, Yang F, Jia R, Yan P, Ma L
Food & function 2020 Nov 18;11(11):9752-9763

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Identification of Milk Fat Metabolism-Related Pathways of the Bovine Mammary Gland during Mid and Late Lactation and Functional Verification of the ACSL4 Gene.

Fan Y, Han Z, Lu X, Zhang H, Arbab AAI, Loor JJ, Yang Y, Yang Z
Genes 2020 Nov 16;11(11)

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Eurocristatine, a plant alkaloid from Eurotium cristatum, alleviates insulin resistance in db/db diabetic mice via activation of PI3K/AKT signaling pathway.

Zhang H, Hui J, Yang J, Deng J, Fan D
European journal of pharmacology 2020 Nov 15;887:173557

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Baicalein ameliorates ionizing radiation-induced injuries by rebalancing gut microbiota and inhibiting apoptosis.

Wang M, Dong Y, Wu J, Li H, Zhang Y, Fan S, Li D
Life sciences 2020 Nov 15;261:118463

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A novel polysaccharide from Acorus tatarinowii protects against LPS-induced neuroinflammation and neurotoxicity by inhibiting TLR4-mediated MyD88/NF-κB and PI3K/Akt signaling pathways.

Zhong J, Qiu X, Yu Q, Chen H, Yan C
International journal of biological macromolecules 2020 Nov 15;163:464-475

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Binding properties of marine bromophenols with human protein tyrosine phosphatase 1B: Molecular docking, surface plasmon resonance and cellular insulin resistance study.

Luo J, Zhang R, Wang X, Hou Z, Guo S, Jiang B
International journal of biological macromolecules 2020 Nov 15;163:200-208

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Targeting HMGB3/hTERT axis for radioresistance in cervical cancer.

Li Z, Zhang Y, Sui S, Hua Y, Zhao A, Tian X, Wang R, Guo W, Yu W, Zou K, Deng W, He L, Zou L
Journal of experimental & clinical cancer research : CR 2020 Nov 13;39(1):243

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Synergism of TNF-α and IFN-γ triggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes.

Karki R, Sharma BR, Tuladhar S, Williams EP, Zalduondo L, Samir P, Zheng M, Sundaram B, Banoth B, Malireddi RKS, Schreiner P, Neale G, Vogel P, Webby R, Jonsson CB, Kanneganti TD
bioRxiv : the preprint server for biology 2020 Nov 13;

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Duck enteritis virus pUL47, as a late structural protein localized in the nucleus, mainly depends on residues 40 to 50 and 768 to 777 and inhibits IFN-β signalling by interacting with STAT1.

He T, Wang M, Cheng A, Yang Q, Jia R, Wu Y, Huang J, Chen S, Zhao XX, Liu M, Zhu D, Zhang S, Ou X, Mao S, Gao Q, Sun D, Wen X, Tian B, Liu Y, Yu Y, Zhang L, Pan L, Chen X
Veterinary research 2020 Nov 11;51(1):135

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Immunoproteasome is up-regulated in rotenone-induced Parkinson's disease rat model.

Sun C, Jia G, Wang X, Wang Y, Liu Y
Neuroscience letters 2020 Nov 1;738:135360

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Berberine inhibits proliferation and induces G0/G1 phase arrest in colorectal cancer cells by downregulating IGF2BP3.

Zhang Y, Liu X, Yu M, Xu M, Xiao Y, Ma W, Huang L, Li X, Ye X
Life sciences 2020 Nov 1;260:118413

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iTRAQ-based quantitative proteomic analysis of the therapeutic effects of 2% hydrogen gas inhalation on brain injury in septic mice.

Xie K, Lian N, Kan Y, Yang M, Pan J, Yu Y, Yu Y
Brain research 2020 Nov 1;1746:147003

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Combination of N, N'-dicyclohexyl-N-arachidonic acylurea and tacrolimus prolongs cardiac allograft survival in mice.

An K, Qin Q, Yu S, Xue M, Wang Z, Lin Q, Ma Y, Yan G, Mo S, Chen Y, Zhang L, Zhong J, Qi Z, Xia J
Immunology and cell biology 2020 May;98(5):382-396

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5-HT(1A)R alleviates Aβ-induced cognitive decline and neuroinflammation through crosstalk with NF-κB pathway in mice.

Wang M, Zong HF, Chang KW, Han H, Yasir Rizvi M, Iffat Neha S, Li ZY, Yang WN, Qian YH
International immunopharmacology 2020 May;82:106354

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Long non-coding RNA OIP5-AS1 promotes pancreatic cancer cell growth through sponging miR-342-3p via AKT/ERK signaling pathway.

Meng X, Ma J, Wang B, Wu X, Liu Z
Journal of physiology and biochemistry 2020 May;76(2):301-315

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Role of fucosyltransferase IV in the migration and invasion of human melanoma cells.

Shan X, Dong W, Zhang L, Cai X, Zhao Y, Chen Q, Yan Q, Liu J
IUBMB life 2020 May;72(5):942-956

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OGDHL silencing promotes hepatocellular carcinoma by reprogramming glutamine metabolism.

Dai W, Xu L, Yu X, Zhang G, Guo H, Liu H, Song G, Weng S, Dong L, Zhu J, Liu T, Guo C, Shen X
Journal of hepatology 2020 May;72(5):909-923

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miR-142-5P regulates triglyceride by targeting CTNNB1 in goat mammary epithelial cells.

Sui M, Wang Z, Xi D, Wang H
Reproduction in domestic animals = Zuchthygiene 2020 May;55(5):613-623

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Transcriptome sequencing analysis of mono‑ADP‑ribosylation in colorectal cancer cells.

Zhang NN, Lin T, Xiao M, Li QS, Li X, Yang L, Wang CL, Wang YL
Oncology reports 2020 May;43(5):1413-1428

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Annexin-1 Mimetic Peptide Ac2-26 Suppresses Inflammatory Mediators in LPS-Induced Astrocytes and Ameliorates Pain Hypersensitivity in a Rat Model of Inflammatory Pain.

Luo Z, Wang H, Fang S, Li L, Li X, Shi J, Zhu M, Tan Z, Lu Z
Cellular and molecular neurobiology 2020 May;40(4):569-585

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Mitochondrial dysfunction is involved in aristolochic acid I-induced apoptosis in renal proximal tubular epithelial cells.

Liu X, Wu J, Wang J, Feng X, Wu H, Huang R, Fan J, Yu X, Yang X
Human & experimental toxicology 2020 May;39(5):673-682

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Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.

Wang Y, Chen J, Li S, Zhang X, Guo Z, Hu J, Shao X, Song N, Zhao Y, Li H, Yang G, Xu C, Wei C
Redox biology 2020 May;32:101514

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Programmable prodrug micelle with size-shrinkage and charge-reversal for chemotherapy-improved IDO immunotherapy.

Dai L, Li X, Yao M, Niu P, Yuan X, Li K, Chen M, Fu Z, Duan X, Liu H, Cai K, Yang H
Biomaterials 2020 May;241:119901

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Lin28a protects against diabetic cardiomyopathy through Mst1 inhibition.

You P, Cheng Z, He X, Deng J, Diao J, Chen H, Cheng G
Journal of cellular physiology 2020 May;235(5):4455-4465

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PM2.5 in poultry houses synergizes with Pseudomonas aeruginosa to aggravate lung inflammation in mice through the NF-κB pathway.

Li M, Wei X, Li Y, Feng T, Jiang L, Zhu H, Yu X, Tang J, Chen G, Zhang J, Zhang X
Journal of veterinary science 2020 May;21(3):e46

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Shear stress stimulates integrin β1 trafficking and increases directional migration of cancer cells via promoting deacetylation of microtubules.

Tang K, Li S, Li P, Xia Q, Yang R, Li T, Li L, Jiang Y, Qin X, Yang H, Wu C, You F, Tan Y, Liu Y
Biochimica et biophysica acta. Molecular cell research 2020 May;1867(5):118676

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TOPORS, a tumor suppressor protein, contributes to the maintenance of higher-order chromatin architecture.

Ji L, Huo X, Zhang Y, Yan Z, Wang Q, Wen B
Biochimica et biophysica acta. Gene regulatory mechanisms 2020 May;1863(5):194518

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Protective effect of cilastatin against diclofenac-induced nephrotoxicity through interaction with diclofenac acyl glucuronide via organic anion transporters.

Huo X, Meng Q, Wang C, Wu J, Wang C, Zhu Y, Ma X, Sun H, Liu K
British journal of pharmacology 2020 May;177(9):1933-1948

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Palmatine induces G2/M phase arrest and mitochondrial-associated pathway apoptosis in colon cancer cells by targeting AURKA.

Liu X, Zhang Y, Wu S, Xu M, Shen Y, Yu M, Fan J, Wei S, Xu C, Huang L, Zhao H, Li X, Ye X
Biochemical pharmacology 2020 May;175:113933

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Protective effect of ginsenoside Rg5 against kidney injury via inhibition of NLRP3 inflammasome activation and the MAPK signaling pathway in high-fat diet/streptozotocin-induced diabetic mice.

Zhu Y, Zhu C, Yang H, Deng J, Fan D
Pharmacological research 2020 May;155:104746

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Elevated SRC3 expression predicts pemetrexed resistance in lung adenocarcinoma.

Chen Y, Sun Y, Zhao W, Ma Y, Yan Z, Nie X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109958

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LncRNA MFI2-AS1 promotes HCC progression and metastasis by acting as a competing endogenous RNA of miR-134 to upregulate FOXM1 expression.

Wei Y, Wang Z, Zong Y, Deng D, Chen P, Lu J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109890

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Protein kinase CK2 participates in estrogen-mediated endothelial progenitor cell homing to endometriotic lesions through stromal cells in a stromal cell-derived factor-1- CXCR4-dependent manner.

Zhao R, Feng D, Zhuang G, Liu Y, Chi S, Zhang J, Zhou X, Zhang W, Wang H
Fertility and sterility 2020 May;113(5):1067-1079.e5

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BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma.

Yu YP, Cai LC, Wang XY, Cheng SY, Zhang DM, Jian WG, Wang TD, Yang JK, Yang KB, Zhang C
Cancer science 2020 May;111(5):1555-1566

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Suppression of experimental atrial fibrillation in a canine model of rapid atrial pacing by the phosphodiesterase 3 inhibitor cilostazol.

Zhao Z, Li R, Wang X, Li J, Xu X, Liu T, Liu E, Li G
Journal of electrocardiology 2020 May-Jun;60:151-158

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Mitochondria-related miR-574 reduces sperm ATP by targeting ND5 in aging males.

Ma J, Chen Q, Wang S, Ma R, Jing J, Yang Y, Feng Y, Zou Z, Zhang Y, Ge X, Xue T, Liang K, Cao S, Wang D, Chen L, Yao B
Aging 2020 May 7;12(9):8321-8338

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Rare Neurologic Disease-Associated Mutations of AIMP1 are Related with Inhibitory Neuronal Differentiation Which is Reversed by Ibuprofen.

Takeuchi Y, Tanaka M, Okura N, Fukui Y, Noguchi K, Hayashi Y, Torii T, Ooizumi H, Ohbuchi K, Mizoguchi K, Miyamoto Y, Yamauchi J
Medicines (Basel, Switzerland) 2020 May 6;7(5)

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Artesunate attenuates 2, 4-dinitrochlorobenzene-induced atopic dermatitis by down-regulating Th17 cell responses in BALB/c mice.

Bai XY, Liu P, Chai YW, Wang Y, Ren SH, Li YY, Zhou H
European journal of pharmacology 2020 May 5;874:173020

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Effect of miR-195-5p on cardiomyocyte apoptosis in rats with heart failure by regulating TGF-β1/Smad3 signaling pathway.

Xie C, Qi H, Huan L, Yang Y
Bioscience reports 2020 May 29;40(5)

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TET2-mediated Cdkn2A DNA hydroxymethylation in midbrain dopaminergic neuron injury of Parkinson's disease.

Wu TT, Liu T, Li X, Chen YJ, Chen TJ, Zhu XY, Chen JL, Li Q, Liu Y, Feng Y, Wu YC
Human molecular genetics 2020 May 28;29(8):1239-1252

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The Lumiptosome, an engineered luminescent form of the apoptosome can report cell death by using the same Apaf-1 dependent pathway.

Hosseini ES, Nikkhah M, Hamidieh AA, Fearnhead HO, Concordet JP, Hosseinkhani S
Journal of cell science 2020 May 27;133(10)

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P-21-activated kinase 1 contributes to tumor angiogenesis upon photodynamic therapy via the HIF-1α/VEGF pathway.

Jiang S, Gao Y, Yu QH, Li M, Cheng X, Hu SB, Song ZF, Zheng QC
Biochemical and biophysical research communications 2020 May 21;526(1):98-104

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Neddylation-mediated Nedd4-2 activation regulates ubiquitination modification of renal NBCe1.

Tu J, Zhang B, Fang G, Chang W, Zhao Y
Experimental cell research 2020 May 15;390(2):111958

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Concentration and Duration of Indoxyl Sulfate Exposure Affects Osteoclastogenesis by Regulating NFATc1 via Aryl Hydrocarbon Receptor.

Liu WC, Shyu JF, Lim PS, Fang TC, Lu CL, Zheng CM, Hou YC, Wu CC, Lin YF, Lu KC
International journal of molecular sciences 2020 May 15;21(10)

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Androgen aggravates liver fibrosis by activation of NLRP3 inflammasome in CCl(4)-induced liver injury mouse model.

Ma X, Zhou Y, Qiao B, Jiang S, Shen Q, Han Y, Liu A, Chen X, Wei L, Zhou L, Zhao J
American journal of physiology. Endocrinology and metabolism 2020 May 1;318(5):E817-E829

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In vitro and in vivo anti-Listeria effect of Succinoglycan Riclin through regulating MAPK/IL-6 axis and metabolic profiling.

Wu Z, Cheng Y, Yang Y, Gao Y, Sun X, Wang L, Sun Q, Zhang J, Xu X
International journal of biological macromolecules 2020 May 1;150:802-813

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Blueberry Prevents the Bladder Dysfunction in Bladder Outlet Obstruction Rats by Attenuating Oxidative Stress and Suppressing Bladder Remodeling.

Miyazaki N, Katsura R, Hamada K, Suzutani T
Nutrients 2020 May 1;12(5)

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Ketamine attenuates high-glucose-mediated endothelial inflammation in human umbilical vein endothelial cells.

Wang T, Zhu H, Hou Y, Duan W, Meng F, Liu Y
Canadian journal of physiology and pharmacology 2020 Mar;98(3):156-161

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Interleukin-4 Restores Insulin Sensitivity in Insulin-Resistant Osteoblasts by Increasing the Expression of Insulin Receptor Substrate 1.

Chao R, Li D, Yue Z, Huang C, Kou Y, Zhou Q, Gao Y, Hasegawa T, Guo J, Li M
Biochemistry. Biokhimiia 2020 Mar;85(3):334-343

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NLRP6 expressed in astrocytes aggravates neurons injury after OGD/R through activating the inflammasome and inducing pyroptosis.

Zhang J, Jiang N, Zhang L, Meng C, Zhao J, Wu J
International immunopharmacology 2020 Mar;80:106183

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Dihydroartemisinin inhibits the proliferation of IgAN mesangial cells through the mTOR signaling pathway.

Xia M, Liu D, Tang X, Liu Y, Liu H, Liu Y, Chen G, Liu H
International immunopharmacology 2020 Mar;80:106125

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JTE-013 supplementation improves erectile dysfunction in rats with streptozotocin-induced type Ⅰ diabetes through the inhibition of the rho-kinase pathway, fibrosis, and apoptosis.

Liu K, Cui K, Feng H, Li R, Lin H, Chen Y, Zhang Y, Chen Z, Yuan H, Li M, Wang T, Lan R, Liu J, Rao K, Wen B
Andrology 2020 Mar;8(2):497-508

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Danshen formula granule and salvianic acid A alleviate ethanol-induced neurotoxicity.

Li Y, Chen H, Yang Y, Niu M, Wang J, Wu Y, Niu L, Liu H, Bao D
Journal of natural medicines 2020 Mar;74(2):399-408

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RNF8 promotes efficient DSB repair by inhibiting the pro-apoptotic activity of p53 through regulating the function of Tip60.

Chen H, Shan J, Liu J, Feng Y, Ke Y, Qi W, Liu W, Zeng X
Cell proliferation 2020 Mar;53(3):e12780

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Resveratrol protects the integrity of alveolar epithelial barrier via SIRT1/PTEN/p-Akt pathway in methamphetamine-induced chronic lung injury.

Wang X, Liu M, Zhu MJ, Shi L, Liu L, Zhao YL, Cheng L, Gu YJ, Zhou MY, Chen L, Kumar A, Wang Y
Cell proliferation 2020 Mar;53(3):e12773

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Integrin β3 Modulates TLR4-Mediated Inflammation by Regulation of CD14 Expression in Macrophages in Septic Condition.

Chen Z, Wang S, Chen Y, Shao Z, Yu Z, Mei S, Li Q
Shock (Augusta, Ga.) 2020 Mar;53(3):335-343

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Inhibitory mechanism of muscone in liver cancer involves the induction of apoptosis and autophagy.

Qi W, Li Z, Yang C, Jiangshan Dai J, Zhang Q, Wang D, Wu C, Xia L, Xu S
Oncology reports 2020 Mar;43(3):839-850

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Samarium enriches antitumor activity of ZnO nanoparticles via downregulation of CXCR4 receptor and cytochrome P450.

Nabeel AI
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2020 Mar;42(3):1010428320909999

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Cyclovirobuxine D Exerts Anticancer Effects by Suppressing the EGFR-FAK-AKT/ERK1/2-Slug Signaling Pathway in Human Hepatocellular Carcinoma.

Zhang J, Chen Y, Lin J, Jia R, An T, Dong T, Zhang Y, Yang X
DNA and cell biology 2020 Mar;39(3):355-367

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Lysophosphatidic acid receptor 4 regulates osteogenic and adipogenic differentiation of progenitor cells via inactivation of RhoA/ROCK1/β-catenin signaling.

Xie Y, Wang X, Wu X, Tian L, Zhou J, Li X, Wang B
Stem cells (Dayton, Ohio) 2020 Mar;38(3):451-463

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HUWE1 promotes EGFR ubiquitination and degradation to protect against renal tubulointerstitial fibrosis.

Zhu Q, Dong H, Bukhari AA, Zhao A, Li M, Sun Y, Zhang X, Cao C, Su D, Liang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4591-4601

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Molecular hydrogen regulates PTEN-AKT-mTOR signaling via ROS to alleviate peritoneal dialysis-related peritoneal fibrosis.

Lu H, Chen W, Liu W, Si Y, Zhao T, Lai X, Kang Z, Sun X, Guo Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4134-4146

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Recombinant Human Milk Fat Globule-Epidermal Growth Factor 8 Attenuates Microthrombosis after Subarachnoid Hemorrhage in Rats.

Wang J, Zuo Y, Zhuang K, Luo K, Yan X, Li J, Zhang JH, Liu F
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2020 Mar;29(3):104536

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Blockade of HSP70 by VER-155008 synergistically enhances bortezomib-induced cytotoxicity in multiple myeloma.

Huang L, Wang Y, Bai J, Yang Y, Wang F, Feng Y, Zhang R, Li F, Zhang P, Lv N, Lei L, Hu J, He A
Cell stress & chaperones 2020 Mar;25(2):357-367

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The marine-derived furanone reduces intracellular lipid accumulation in vitro by targeting LXRα and PPARα.

Li T, Hu SM, Pang XY, Wang JF, Yin JY, Li FH, Wang J, Yang XQ, Xia B, Liu YH, Song WG, Guo SD
Journal of cellular and molecular medicine 2020 Mar;24(6):3384-3398

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Mechanism of the hypoxia inducible factor 1/hypoxic response element pathway in rat myocardial ischemia/diazoxide post‑conditioning.

Li J, Zhou W, Chen W, Wang H, Zhang Y, Yu T
Molecular medicine reports 2020 Mar;21(3):1527-1536

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Ginsenosides reduce body weight and ameliorate hepatic steatosis in high fat diet‑induced obese mice via endoplasmic reticulum stress and p‑STAT3/STAT3 signaling.

Yao Y
Molecular medicine reports 2020 Mar;21(3):1059-1070

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Cystatin C promotes cognitive dysfunction in rats with cerebral microbleeds by inhibiting the ERK/synapsin Ia/Ib pathway.

Yu G, Sun X, Li L, Huang L, Liu H, Wang S, Ren Z, Zhang Y
Experimental and therapeutic medicine 2020 Mar;19(3):2282-2290

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WHIMP links the actin nucleation machinery to Src-family kinase signaling during protrusion and motility.

Kabrawala S, Zimmer MD, Campellone KG
PLoS genetics 2020 Mar;16(3):e1008694

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LongShengZhi capsule inhibits doxorubicin-induced heart failure by anti-oxidative stress.

Xu S, Wang Y, Yu M, Wang D, Liang Y, Chen Y, Liao C, Xie Z, Zhao B, Han J, Duan Y, Yang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109803

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The mechanism of PDA/PEI/5-Fu coated esophageal stent material on inhibiting cancer associated pathological cells.

Zhang K, Bai Y, Xu R, Li J, Guan F
Journal of biomedical materials research. Part A 2020 Mar;108(3):814-821

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DJ-1 exerts anti-inflammatory effects and regulates NLRX1-TRAF6 via SHP-1 in stroke.

Peng L, Zhou Y, Jiang N, Wang T, Zhu J, Chen Y, Li L, Zhang J, Yu S, Zhao Y
Journal of neuroinflammation 2020 Mar 9;17(1):81

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Transcription co-activator P300 activates Elk1-aPKC-ι signaling mediated epithelial-to-mesenchymal transition and malignancy in hepatocellular carcinoma.

Ma C, Huang S, Xu L, Tian L, Yang Y, Wang J
Oncogenesis 2020 Mar 6;9(3):32

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Quantitative Mitochondrial Proteomics Reveals ANXA7 as a Crucial Factor in Mitophagy.

Meng K, Lu S, Yan X, Sun Y, Gao J, Wang Y, Yin X, Sun Z, He QY
Journal of proteome research 2020 Mar 6;19(3):1275-1284

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miR-17 regulates the proliferation and differentiation of retinal progenitor cells by targeting CHMP1A.

Sun N, Zhang D, Ni N, Tang Z, Gao H, Ju Y, Dai X, Wang J, Gu P, Ji J
Biochemical and biophysical research communications 2020 Mar 5;523(2):493-499

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SIRT3 inhibits cardiac hypertrophy by regulating PARP-1 activity.

Feng X, Wang Y, Chen W, Xu S, Li L, Geng Y, Shen A, Gao H, Zhang L, Liu S
Aging 2020 Mar 4;12(5):4178-4192

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BCAP31, a cancer/testis antigen-like protein, can act as a probe for non-small-cell lung cancer metastasis.

Wang J, Jiang D, Li Z, Yang S, Zhou J, Zhang G, Zhang Z, Sun Y, Zhang Z, Li X, Tao L, Shi J, Lu Y, Zheng L, Song C, Yang K
Scientific reports 2020 Mar 4;10(1):4025

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(20S)G-Rh2 Inhibits NF-κB Regulated Epithelial-Mesenchymal Transition by Targeting Annexin A2.

Wang YS, Li H, Li Y, Zhang S, Jin YH
Biomolecules 2020 Mar 31;10(4)

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The Agpat4/LPA axis in colorectal cancer cells regulates antitumor responses via p38/p65 signaling in macrophages.

Zhang D, Shi R, Xiang W, Kang X, Tang B, Li C, Gao L, Zhang X, Zhang L, Dai R, Miao H
Signal transduction and targeted therapy 2020 Mar 27;5(1):24

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LINC00978 promotes hepatocellular carcinoma carcinogenesis partly via activating the MAPK/ERK pathway.

Zhang Q, Cheng S, Cao L, Yang J, Wang Y, Chen Y
Bioscience reports 2020 Mar 27;40(3)

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Posttranslational lysine 2-hydroxyisobutyrylation of human sperm tail proteins affects motility.

Cheng YM, Peng Z, Chen HY, Pan TT, Hu XN, Wang F, Luo T
Human reproduction (Oxford, England) 2020 Mar 27;35(3):494-503

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Design, Synthesis, and Biological Evaluation of Imidazo[1,2-a]pyridine Derivatives as Novel PI3K/mTOR Dual Inhibitors.

Yu Y, Han Y, Zhang F, Gao Z, Zhu T, Dong S, Ma M
Journal of medicinal chemistry 2020 Mar 26;63(6):3028-3046

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Optimization of Experimental Variables Influencing Apoptosome Biosensor in HEK293T Cells.

Oladzad A, Nikkhah M, Hosseinkhani S
Sensors (Basel, Switzerland) 2020 Mar 23;20(6)

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Protective effects of panax notoginseng saponin on dextran sulfate sodium-induced colitis in rats through phosphoinositide-3-kinase protein kinase B signaling pathway inhibition.

Lu QG, Zeng L, Li XH, Liu Y, Du XF, Bai GM, Yan X
World journal of gastroenterology 2020 Mar 21;26(11):1156-1171

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Extrahepatic deficiency of transferrin receptor 2 is associated with increased erythropoiesis independent of iron overload.

Wortham AM, Goldman DC, Chen J, Fleming WH, Zhang AS, Enns CA
The Journal of biological chemistry 2020 Mar 20;295(12):3906-3917

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Dual regulation of p53 by the ribosome maturation factor SBDS.

Hao Q, Wang J, Chen Y, Wang S, Cao M, Lu H, Zhou X
Cell death & disease 2020 Mar 20;11(3):197

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Regulation of the linear ubiquitination of STAT1 controls antiviral interferon signaling.

Zuo Y, Feng Q, Jin L, Huang F, Miao Y, Liu J, Xu Y, Chen X, Zhang H, Guo T, Yuan Y, Zhang L, Wang J, Zheng H
Nature communications 2020 Mar 2;11(1):1146

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HNF-1a promotes pancreatic cancer growth and apoptosis resistance via its target gene PKLR.

Fan Z, Fan K, Deng S, Gong Y, Qian Y, Huang Q, Yang C, Cheng H, Jin K, Luo G, Liu C, Yu X
Acta biochimica et biophysica Sinica 2020 Mar 18;52(3):241-250

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Alarmin HMGB1 Plays a Detrimental Role in Hippocampal Dysfunction Caused by Hypoxia-Ischemia Insult in Neonatal Mice: Evidence from the Application of the HMGB1 Inhibitor Glycyrrhizin.

Le K, Wu S, Chibaatar E, Ali AI, Guo Y
ACS chemical neuroscience 2020 Mar 18;11(6):979-993

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Identification of ALPPL2 as a Naive Pluripotent State-Specific Surface Protein Essential for Human Naive Pluripotency Regulation.

Bi Y, Tu Z, Zhang Y, Yang P, Guo M, Zhu X, Zhao C, Zhou J, Wang H, Wang Y, Gao S
Cell reports 2020 Mar 17;30(11):3917-3931.e5

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TXNIP deficiency mitigates podocyte apoptosis via restraining the activation of mTOR or p38 MAPK signaling in diabetic nephropathy.

Song S, Qiu D, Wang Y, Wei J, Wu H, Wu M, Wang S, Zhou X, Shi Y, Duan H
Experimental cell research 2020 Mar 15;388(2):111862

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[Effect of human placental mesenchymal stem cells transplantation on pulmonary vascular endothelial permeability and lung injury repair in mice with acute lung injury].

Xu M, Li X, Ma C, Lü Y, Ma X, Ma X
Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 2020 Mar 15;34(3):387-392

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Synergetic inhibition of daidzein and regular exercise on breast cancer in bearing-4T1 mice by regulating NK cells and apoptosis pathway.

Wang B, Xu H, Hu X, Ma W, Zhang J, Li Y, Yu M, Zhang Y, Li X, Ye X
Life sciences 2020 Mar 15;245:117387

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Neuronal BIN1 Regulates Presynaptic Neurotransmitter Release and Memory Consolidation.

De Rossi P, Nomura T, Andrew RJ, Masse NY, Sampathkumar V, Musial TF, Sudwarts A, Recupero AJ, Le Metayer T, Hansen MT, Shim HN, Krause SV, Freedman DJ, Bindokas VP, Kasthuri N, Nicholson DA, Contractor A, Thinakaran G
Cell reports 2020 Mar 10;30(10):3520-3535.e7

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HIF2-Induced Long Noncoding RNA RAB11B-AS1 Promotes Hypoxia-Mediated Angiogenesis and Breast Cancer Metastasis.

Niu Y, Bao L, Chen Y, Wang C, Luo M, Zhang B, Zhou M, Wang JE, Fang YV, Kumar A, Xing C, Wang Y, Luo W
Cancer research 2020 Mar 1;80(5):964-975

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Microcystins-LR induced apoptosis via S-nitrosylation of GAPDH in colorectal cancer cells.

Li K, Huang M, Xu P, Wang M, Ye S, Wang Q, Zeng S, Chen X, Gao W, Chen J, Zhang Q, Zhong Z, Sun Y, Liu Q
Ecotoxicology and environmental safety 2020 Mar 1;190:110096

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Ferulic acid isolated from propolis inhibits porcine parvovirus replication potentially through Bid-mediate apoptosis.

Ma X, Guo Z, Zhang Z, Li X, Wang X, Liu Y, Wang X
International immunopharmacology 2020 Jun;83:106379

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Histone demethylase KDM4A regulates adipogenic and osteogenic differentiation via epigenetic regulation of C/EBPα and canonical Wnt signaling.

Qi Q, Wang Y, Wang X, Yang J, Xie Y, Zhou J, Li X, Wang B
Cellular and molecular life sciences : CMLS 2020 Jun;77(12):2407-2421

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ARHGEF38 as a novel biomarker to predict aggressive prostate cancer.

Liu K, Wang A, Ran L, Zhang W, Jing S, Wang Y, Zhang X, Liu G, Sen W, Song F
Genes & diseases 2020 Jun;7(2):217-224

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Reversing a model of Parkinson's disease with in situ converted nigral neurons.

Qian H, Kang X, Hu J, Zhang D, Liang Z, Meng F, Zhang X, Xue Y, Maimon R, Dowdy SF, Devaraj NK, Zhou Z, Mobley WC, Cleveland DW, Fu XD
Nature 2020 Jun;582(7813):550-556

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MiR-153-3p induces immune dysregulation by inhibiting PELI1 expression in umbilical cord-derived mesenchymal stem cells in patients with systemic lupus erythematosus.

Li D, Li X, Duan M, Dou Y, Feng Y, Nan N, Zhang W
Autoimmunity 2020 Jun;53(4):201-209

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PAQR3 protects against oxygen-glucose deprivation/reperfusion-induced injury through the ERK signaling pathway in N2A cells.

Peng W, Mo X, Li L, Lu T, Hu Z
Journal of molecular histology 2020 Jun;51(3):307-315

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Clinical significance of sHER2‑ECD and calpain‑10 expression in tumor tissues of patients with breast cancer.

Ding Y, Ma M, Li Q, Gao S, Li S, Liu J, Geng C
Oncology reports 2020 Jun;43(6):2093-2104

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Esculetin Ameliorates Lipopolysaccharide-Induced Acute Lung Injury in Mice Via Modulation of the AKT/ERK/NF-κB and RORγt/IL-17 Pathways.

Lee HC, Liu FC, Tsai CN, Chou AH, Liao CC, Yu HP
Inflammation 2020 Jun;43(3):962-974

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Quercetin suppresses migration and invasion by targeting miR-146a/GATA6 axis in fibroblast-like synoviocytes of rheumatoid arthritis.

Zhao J, Chen B, Peng X, Wang C, Wang K, Han F, Xu J
Immunopharmacology and immunotoxicology 2020 Jun;42(3):221-227

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Inhibition of miR-574-5p suppresses cell growth and metastasis and enhances chemosensitivity by targeting RNA binding protein QKI in cervical cancer cells.

Tong R, Zhang J, Wang C, Li Q, Wang L, Ju M
Naunyn-Schmiedeberg's archives of pharmacology 2020 Jun;393(6):951-966

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Human placenta derived mesenchymal stromal cells alleviate GVHD by promoting the generation of GSH and GST in PD-1(+)T cells.

Zhuoya W, Nannan Z, Aiping Z, Guoyan W, Menghua D, Jiashen Z, Yanlian X, Xiying L
Cellular immunology 2020 Jun;352:104083

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Regulatory T cell is critical for interleukin-33-mediated neuroprotection against stroke.

Liu X, Hu R, Pei L, Si P, Wang C, Tian X, Wang X, Liu H, Wang B, Xia Z, Xu Y, Song B
Experimental neurology 2020 Jun;328:113233

---

SUMOylation of vascular endothelial growth factor receptor 2 inhibits the proliferation, migration, and angiogenesis signaling pathway in non-small cell lung cancer.

Wang M, Jiang X
Anti-cancer drugs 2020 Jun;31(5):492-499

---

Tizoxanide mitigates inflammatory response in LPS-induced neuroinflammation in microglia via restraining p38/MAPK pathway.

Li XW, He RZ, Li Y, Ruan ZF
European review for medical and pharmacological sciences 2020 Jun;24(11):6446-6454

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Astrocyte elevated gene 1 (AEG-1) promotes anoikis resistance and metastasis by inducing autophagy in hepatocellular carcinoma.

Zhu HD, Liu L, Deng H, Li ZB, Sheng JQ, He XX, Tian DA, Li PY
Journal of cellular physiology 2020 Jun;235(6):5084-5095

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Disregulation of Autophagy in the Transgenerational Cc2d1a Mouse Model of Autism.

Dana H, Bayramov KK, Delibaşı N, Tahtasakal R, Bayramov R, Hamurcu Z, Sener EF
Neuromolecular medicine 2020 Jun;22(2):239-249

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The Activation of Heat-Shock Protein After Copper(II) and/or Arsenic(III)-Induced Imbalance of Homeostasis, Inflammatory Response in Chicken Rectum.

Yang X, Zhao H, Wang Y, Liu J, Guo M, Fei D, Mu M, Xing M
Biological trace element research 2020 Jun;195(2):613-623

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BRM-SWI/SNF chromatin remodeling complex enables functional telomeres by promoting co-expression of TRF2 and TRF1.

Wu S, Ge Y, Li X, Yang Y, Zhou H, Lin K, Zhang Z, Zhao Y
PLoS genetics 2020 Jun;16(6):e1008799

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Dendrobium officinale polysaccharides protected against ethanol-induced acute liver injury in vivo and in vitro via the TLR4/NF-κB signaling pathway.

Yang K, Zhan L, Lu T, Zhou C, Chen X, Dong Y, Lv G, Chen S
Cytokine 2020 Jun;130:155058

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Sustained mitochondrial biogenesis is essential to maintain caloric restriction-induced beige adipocytes.

Mooli RGR, Mukhi D, Watt M, Edmunds L, Xie B, Capooci J, Reslink M, Eze C, Mills A, Stolz DB, Jurczak M, Ramakrishnan SK
Metabolism: clinical and experimental 2020 Jun;107:154225

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Tolfenamic acid inhibits GSK-3β and PP2A mediated tau hyperphosphorylation in Alzheimer's disease models.

Zhang H, Wang X, Xu P, Ji X, Chi T, Liu P, Zou L
The journal of physiological sciences : JPS 2020 Jun 9;70(1):29

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Highly expressed STAT1 contributes to the suppression of stemness properties in human paclitaxel-resistant ovarian cancer cells.

Wang F, Zhang L, Liu J, Zhang J, Xu G
Aging 2020 Jun 9;12(11):11042-11060

---

Arsenic induces dysfunctional autophagy via dual regulation of mTOR pathway and Beclin1-Vps34/PI3K complex in MLTC-1 cells.

Liang C, Feng Z, Manthari RK, Wang C, Han Y, Fu W, Wang J, Zhang J
Journal of hazardous materials 2020 Jun 5;391:122227

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The GTPase Rab27b regulates the release, autophagic clearance, and toxicity of α-synuclein.

Underwood R, Wang B, Carico C, Whitaker RH, Placzek WJ, Yacoubian TA
The Journal of biological chemistry 2020 Jun 5;295(23):8005-8016

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BDH2 triggers ROS-induced cell death and autophagy by promoting Nrf2 ubiquitination in gastric cancer.

Liu JZ, Hu YL, Feng Y, Jiang Y, Guo YB, Liu YF, Chen X, Yang JL, Chen YY, Mao QS, Xue WJ
Journal of experimental & clinical cancer research : CR 2020 Jun 30;39(1):123

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Enterovirus A71 Oncolysis of Malignant Gliomas.

Zhang X, Wang H, Sun Y, Qi M, Li W, Zhang Z, Zhang XE, Cui Z
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Jun 3;28(6):1533-1546

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Cytoplasmic PCNA is located in the actin belt and involved in osteoclast differentiation.

Tang D, Liu X, Chen K, Li Z, Dai Y, Xu J, Zhang HT, Gao X, Liu L
Aging 2020 Jun 27;12(13):13297-13317

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MiR-377-3p inhibits atherosclerosis-associated vascular smooth muscle cell proliferation and migration via targeting neuropilin2.

Wang H, Wei Z, Li H, Guan Y, Han Z, Wang H, Liu B
Bioscience reports 2020 Jun 26;40(6)

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Molecular mechanism of targeted inhibition of HMGA2 via miRNAlet-7a in proliferation and metastasis of laryngeal squamous cell carcinoma.

Ma LJ, Wu J, Zhou E, Yin J, Xiao XP
Bioscience reports 2020 Jun 26;40(6)

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Opening large-conductance potassium channels selectively induced cell death of triple-negative breast cancer.

Sizemore G, McLaughlin S, Newman M, Brundage K, Ammer A, Martin K, Pugacheva E, Coad J, Mattes MD, Yu HG
BMC cancer 2020 Jun 26;20(1):595

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Enhanced autophagic retrograde axonal transport by dynein intermediate chain upregulation improves Aβ clearance and cognitive function in APP/PS1 double transgenic mice.

Zhou F, Xiong X, Li S, Liang J, Zhang X, Tian M, Li X, Gao M, Tang L, Li Y
Aging 2020 Jun 24;12(12):12142-12159

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L-3-n-butylphthalide attenuates inflammation response and brain edema in rat intracerebral hemorrhage model.

Zeng Z, Gong X, Hu Z
Aging 2020 Jun 21;12(12):11768-11780

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A Gold(I) Complex Containing an Oleanolic Acid Derivative as a Potential Anti-Ovarian-Cancer Agent by Inhibiting TrxR and Activating ROS-Mediated ERS.

Bian M, Sun Y, Liu Y, Xu Z, Fan R, Liu Z, Liu W
Chemistry (Weinheim an der Bergstrasse, Germany) 2020 Jun 2;26(31):7092-7108

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Excretory/secretory products of Angiostrongylus cantonensis fifth-stage larvae induce endoplasmic reticulum stress via the Sonic hedgehog pathway in mouse astrocytes.

Chen KY, Chen YJ, Cheng CJ, Jhan KY, Wang LC
Parasites & vectors 2020 Jun 18;13(1):317

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Immune profiling reveals prognostic genes in high-grade serous ovarian cancer.

Wu Y, Xia L, Zhao P, Deng Y, Guo Q, Zhu J, Chen X, Ju X, Wu X
Aging 2020 Jun 16;12(12):11398-11415

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Neurotoxicity of aluminum oxide nanoparticles and their mechanistic role in dopaminergic neuron injury involving p53-related pathways.

Liu H, Zhang W, Fang Y, Yang H, Tian L, Li K, Lai W, Bian L, Lin B, Liu X, Xi Z
Journal of hazardous materials 2020 Jun 15;392:122312

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Cerenkov luminescence imaging is an effective preclinical tool for assessing colorectal cancer PD-L1 levels in vivo.

Zhao S, Pan W, Jiang H, Zhang R, Jiang H, Liang Z, Hu H
EJNMMI research 2020 Jun 15;10(1):64

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Mechanism of Heshouwuyin inhibiting the Cyt c/Apaf-1/Caspase-9/Caspase-3 pathway in spermatogenic cell apoptosis.

Wang H, Zhu J, Jiang L, Shan B, Xiao P, Ai J, Li N, Qi F, Niu S
BMC complementary medicine and therapies 2020 Jun 11;20(1):180

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Regulatory effects of Prohibitin 1 on proliferation and apoptosis of pulmonary arterial smooth muscle cells in monocrotaline-induced PAH rats.

Cao YY, Ba HX, Li Y, Tang SY, Luo ZQ, Li XH
Life sciences 2020 Jun 1;250:117548

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Synergistic Effect of Benzethonium Chloride Combined with Endoxan against Hepatocellular Carcinoma in Rats through Targeting Apoptosis Signaling Pathway.

Abozaid OAR, Moawed FSM, Farrag MA, Kawara RSM
Asian Pacific journal of cancer prevention : APJCP 2020 Jun 1;21(6):1709-1716

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Fast and unbiased purification of RNA-protein complexes after UV cross-linking.

Urdaneta EC, Beckmann BM
Methods (San Diego, Calif.) 2020 Jun 1;178:72-82

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Daucosterol linolenate from Sweet Potato Suppresses MCF7-Xenograft-Tumor Growth through Regulating PI3K/AKT Pathway.

Han B, Jiang L, Jiang P, Zhou D, Jia X, Li X, Ye X
Planta medica 2020 Jul;86(11):767-775

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A novel homozygous nonsense ZP1 variant causes human female infertility associated with empty follicle syndrome (EFS).

Xu Q, Zhu X, Maqsood M, Li W, Tong X, Kong S, Wang F, Liu X, Wei Z, Zhang Z, Zhu F, Cao Y, Bao J
Molecular genetics & genomic medicine 2020 Jul;8(7):e1269

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Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation.

Chen Z, Li Z, Hu X, Xie F, Kuang S, Zhan B, Gao W, Chen X, Gao S, Li Y, Wang Y, Qian F, Ding C, Gan J, Ji C, Xu XW, Zhou Z, Huang J, He HH, Li J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2020 Jul;7(14):2000532

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A mitophagic response to iron overload-induced oxidative damage associated with the PINK1/Parkin pathway in pancreatic beta cells.

Zhang L, Hou L, Liu Z, Huang S, Meng Z, Liang L
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2020 Jul;60:126493

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lncRNA LA16c‑313D11.11 modulates the development of endometrial cancer by binding to and inhibiting microRNA‑205‑5p function and indirectly increasing PTEN activity.

Xin W, Zhao S, Han X, Zhao P, Yu H, Gao X, Li P, Wu Q, Ding J, Hua K
International journal of oncology 2020 Jul;57(1):355-363

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Matrix Metalloproteinase 11 as a Novel Tumor Promoter and Diagnostic and Prognostic Biomarker for Pancreatic Ductal Adenocarcinoma.

Zhang X, Lu J, Zhou L, You L, Liang Z, Guo J, Zhao Y
Pancreas 2020 Jul;49(6):812-821

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Characterization of red ginseng-drug interaction by CYP3A activity increased in high dose administration in mice.

Kim Y, Jo JJ, Cho P, Shrestha R, Kim KM, Ki SH, Song KS, Liu KH, Song IS, Kim JH, Lee JM, Lee S
Biopharmaceutics & drug disposition 2020 Jul;41(7):295-306

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HMGB1-induced aberrant autophagy contributes to insulin resistance in granulosa cells in PCOS.

Zhang C, Hu J, Wang W, Sun Y, Sun K
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jul;34(7):9563-9574

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miR-196b-5p controls adipocyte differentiation and lipogenesis through regulating mTORC1 and TGF-β signaling.

Shi Y, Li F, Wang S, Wang C, Xie Y, Zhou J, Li X, Wang B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jul;34(7):9207-9222

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Presynaptic Caytaxin prevents apoptosis via deactivating DAPK1 in the acute phase of cerebral ischemic stroke.

Wang S, Chen K, Yu J, Wang X, Li Q, Lv F, Shen H, Pei L
Experimental neurology 2020 Jul;329:113303

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miR-203a suppresses cell proliferation by targeting RING-finger protein 6 in colorectal cancer.

Miao J, Hou N, Yang W, Jiang Q, Xue W, Wang X, Zhang H, Xiong X, Wang L, Zhao L, Huang C
Anti-cancer drugs 2020 Jul;31(6):583-591

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Stomatin-like protein-2 confers neuroprotection effect in oxygen-glucose deprivation/reoxygenation-injured neurons by regulating AMPK/Nrf2 signalling.

Wang M, Li C, Shi W
Journal of drug targeting 2020 Jul;28(6):600-608

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Protective effect of quercetin on rat testes against cadmium toxicity by alleviating oxidative stress and autophagy.

Wang J, Zhu H, Wang K, Yang Z, Liu Z
Environmental science and pollution research international 2020 Jul;27(20):25278-25286

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BMP7 is Downregulated in Lumbosacral Spinal Cord of Rat Embryos With Anorectal Malformation.

Yang Z, Li X, Jia H, Bai Y, Wang W
The Journal of surgical research 2020 Jul;251:202-210

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Targeted immunomodulation of inflammatory monocytes across the blood-brain barrier by curcumin-loaded nanoparticles delays the progression of experimental autoimmune encephalomyelitis.

Lu L, Qi S, Chen Y, Luo H, Huang S, Yu X, Luo Q, Zhang Z
Biomaterials 2020 Jul;245:119987

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AMPH1 functions as a tumour suppressor in ovarian cancer via the inactivation of PI3K/AKT pathway.

Chen Y, Cao W, Wang L, Zhong T
Journal of cellular and molecular medicine 2020 Jul;24(13):7652-7659

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SIRT2 suppresses expression of inflammatory factors via Hsp90-glucocorticoid receptor signalling.

Sun K, Wang X, Fang N, Xu A, Lin Y, Zhao X, Nazarali AJ, Ji S
Journal of cellular and molecular medicine 2020 Jul;24(13):7439-7450

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CUDC-907, a novel dual PI3K and HDAC inhibitor, in prostate cancer: Antitumour activity and molecular mechanism of action.

Hu C, Xia H, Bai S, Zhao J, Edwards H, Li X, Yang Y, Lyu J, Wang G, Zhan Y, Dong Y, Ge Y
Journal of cellular and molecular medicine 2020 Jul;24(13):7239-7253

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The effect of lncRNA-ARAP1-AS2/ARAP1 on high glucose-induced cytoskeleton rearrangement and epithelial-mesenchymal transition in human renal tubular epithelial cells.

Li L, Xu L, Wen S, Yang Y, Li X, Fan Q
Journal of cellular physiology 2020 Jul;235(7-8):5787-5795

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Reversal of prolonged obesity-associated cerebrovascular dysfunction by inhibiting microglial Tak1.

Shen Q, Chen Z, Zhao F, Pan S, Zhang T, Cheng X, Zhang L, Zhang S, Qi J, Li J, Cai D, Zhang G
Nature neuroscience 2020 Jul;23(7):832-841

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LHPP inhibits hepatocellular carcinoma cell growth and metastasis.

Liao L, Duan D, Liu Y, Chen L
Cell cycle (Georgetown, Tex.) 2020 Jul;19(14):1846-1854

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Melatonin protects against chronic stress-induced oxidative meiotic defects in mice MII oocytes by regulating SIRT1.

Guo Y, Sun J, Bu S, Li B, Zhang Q, Wang Q, Lai D
Cell cycle (Georgetown, Tex.) 2020 Jul;19(13):1677-1695

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Human alkaline ceramidase 2 promotes the growth, invasion, and migration of hepatocellular carcinoma cells via sphingomyelin phosphodiesterase acid-like 3B.

Liu B, Xiao J, Dong M, Qiu Z, Jin J
Cancer science 2020 Jul;111(7):2259-2274

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Bisdemethoxycurcumin inhibits oxidative stress and antagonizes Alzheimer's disease by up-regulating SIRT1.

Xu Y, Hu R, He D, Zhou G, Wu H, Xu C, He B, Wu L, Wang Y, Chang Y, Ma R, Xie M, Xiao Z
Brain and behavior 2020 Jul;10(7):e01655

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Pathological mutations in PNKP trigger defects in DNA single-strand break repair but not DNA double-strand break repair.

Kalasova I, Hailstone R, Bublitz J, Bogantes J, Hofmann W, Leal A, Hanzlikova H, Caldecott KW
Nucleic acids research 2020 Jul 9;48(12):6672-6684

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Integrative Proteomic Characterization of Human Lung Adenocarcinoma.

Xu JY, Zhang C, Wang X, Zhai L, Ma Y, Mao Y, Qian K, Sun C, Liu Z, Jiang S, Wang M, Feng L, Zhao L, Liu P, Wang B, Zhao X, Xie H, Yang X, Zhao L, Chang Y, Jia J, Wang X, Zhang Y, Wang Y, Yang Y, Wu Z, Yang L, Liu B, Zhao T, Ren S, Sun A, Zhao Y, Ying W, Wang F, Wang G, Zhang Y, Cheng S, Qin J, Qian X, Wang Y, Li J, He F, Xiao T, Tan M
Cell 2020 Jul 9;182(1):245-261.e17

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SLC7A2 serves as a potential biomarker and therapeutic target for ovarian cancer.

Sun T, Bi F, Liu Z, Yang Q
Aging 2020 Jul 9;12(13):13281-13296

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Protective effect of miRNA-containing extracellular vesicles derived from mesenchymal stromal cells of old rats on renal function in chronic kidney disease.

Wang Y, Guo YF, Fu GP, Guan C, Zhang X, Yang DG, Shi YC
Stem cell research & therapy 2020 Jul 8;11(1):274

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SNHG11 promotes cell proliferation in colorectal cancer by forming a positive regulatory loop with c-Myc.

Huang W, Dong S, Cha Y, Yuan X
Biochemical and biophysical research communications 2020 Jul 5;527(4):985-992

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The miR-1224-5p/TNS4/EGFR axis inhibits tumour progression in oesophageal squamous cell carcinoma.

Shi ZZ, Wang WJ, Chen YX, Fan ZW, Xie XF, Yang LY, Chang C, Cai Y, Hao JJ, Wang MR, Bai J
Cell death & disease 2020 Jul 30;11(7):597

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Transcriptome Analysis of Testes and Uterus: Reproductive Dysfunction Induced by Toxoplasma gondii in Mice.

Wang J, Liu T, Mahmmod YS, Yang Z, Tan J, Ren Z, Zhang X, Yang X, Zhang XX, Yuan ZG
Microorganisms 2020 Jul 28;8(8)

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NLRP3 inflammasome-mediated microglial pyroptosis is critically involved in the development of post-cardiac arrest brain injury.

Chang Y, Zhu J, Wang D, Li H, He Y, Liu K, Wang X, Peng Y, Pan S, Huang K
Journal of neuroinflammation 2020 Jul 23;17(1):219

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Innate Effector Systems in Primary Human Macrophages Sensitize Multidrug-Resistant Klebsiella pneumoniae to Antibiotics.

Rekha RS, Karadottir H, Ahmed S, Gudmundsson GH, Agerberth B, Bergman P
Infection and immunity 2020 Jul 21;88(8)

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ZIC2 is downregulated and represses tumor growth via the regulation of STAT3 in breast cancer.

Liu ZH, Chen ML, Zhang Q, Zhang Y, An X, Luo YL, Liu XM, Liu SX, Liu Q, Yang T, Liu YM, Liu BL, Zhou AJ, Li MZ, Liu YJ, Liu ZX, Zhong Q
International journal of cancer 2020 Jul 15;147(2):505-518

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Impairment in dynein-mediated nuclear translocation by BICD2 C-terminal truncation leads to neuronal migration defect and human brain malformation.

Tsai MH, Cheng HY, Nian FS, Liu C, Chao NH, Chiang KL, Chen SF, Tsai JW
Acta neuropathologica communications 2020 Jul 14;8(1):106

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Genetic variants in m6A modification genes are associated with esophageal squamous-cell carcinoma in the Chinese population.

Yang N, Ying P, Tian J, Wang X, Mei S, Zou D, Peng X, Gong Y, Yang Y, Zhu Y, Ke J, Zhong R, Chang J, Miao X
Carcinogenesis 2020 Jul 10;41(6):761-768

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Long non-coding RNA JPX correlates with poor prognosis and tumor progression in non-small-cell lung cancer by interacting with miR-145-5p and CCND2.

Jin M, Ren J, Luo M, You Z, Fang Y, Han Y, Li G, Liu H
Carcinogenesis 2020 Jul 10;41(5):634-645

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Excessive Mg(2+) Impairs Intestinal Homeostasis by Enhanced Production of Adenosine Triphosphate and Reactive Oxygen Species.

Hashizume O, Funato Y, Yamazaki D, Miki H
Antioxidants & redox signaling 2020 Jul 1;33(1):20-34

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Carfilzomib inhibits the growth of lung adenocarcinoma via upregulation of Gadd45a expression.

Yang F, Liu WW, Chen H, Zhu J, Huang AH, Zhou F, Gan Y, Zhang YH, Ma L
Journal of Zhejiang University. Science. B 2020 Jan.;21(1):64-76

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Identification and characterization of c-raf from orange-spotted grouper (Epinephelus coioides).

Mo ZQ, Lai XL, Wang WT, Chen HP, He ZC, Han R, Wang JL, Luo XC, Li YW, Dan XM
Fish & shellfish immunology 2020 Jan;96:311-318

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MiR-203a-3p inhibits retinal angiogenesis and alleviates proliferative diabetic retinopathy in oxygen-induced retinopathy (OIR) rat model via targeting VEGFA and HIF-1α.

Han N, Xu H, Yu N, Wu Y, Yu L
Clinical and experimental pharmacology & physiology 2020 Jan;47(1):85-94

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Calycosin-7-O-β-D-glucoside attenuates myocardial ischemia-reperfusion injury by activating JAK2/STAT3 signaling pathway via the regulation of IL-10 secretion in mice.

Liu Y, Che G, Di Z, Sun W, Tian J, Ren M
Molecular and cellular biochemistry 2020 Jan;463(1-2):175-187

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MiR-183-5p protects rat hearts against myocardial ischemia/reperfusion injury through targeting VDAC1.

Lin D, Cui B, Ma J, Ren J
BioFactors (Oxford, England) 2020 Jan;46(1):83-93

---

Decreased ALCAM expression and promoter hypermethylation is associated with preeclampsia.

Wei LL, Pan YS, Tang Q, Yang ZJ, Song WQ, Gao YF, Li J, Zhang L, Liu SG
Hypertension research : official journal of the Japanese Society of Hypertension 2020 Jan;43(1):13-22

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High Expression of c-Met, PKCλ and ALDH1A3 Predicts a Poor Prognosis in Late-stage Breast Cancer.

Motomura H, Nozaki Y, Onaga C, Ozaki A, Tamori S, Shiina TA, Kanai S, Ohira C, Hara Y, Harada Y, Takasawa R, Hanawa T, Tanuma SI, Mano Y, Sato T, Sato K, Akimoto K
Anticancer research 2020 Jan;40(1):35-52

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ALK(ATI) interacts with c-Myc and promotes cancer stem cell-like properties in sarcoma.

Xu BS, Chen HY, Que Y, Xiao W, Zeng MS, Zhang X
Oncogene 2020 Jan;39(1):151-163

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MnTBAP inhibits bone loss in ovariectomized rats by reducing mitochondrial oxidative stress in osteoblasts.

Cao X, Luo D, Li T, Huang Z, Zou W, Wang L, Lian K, Lin D
Journal of bone and mineral metabolism 2020 Jan;38(1):27-37

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LncRNA SNHG3 promotes cell proliferation and invasion through the miR-384/hepatoma-derived growth factor axis in breast cancer.

Ma Q, Qi X, Lin X, Li L, Chen L, Hu W
Human cell 2020 Jan;33(1):232-242

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Hydrogen sulfide attenuates cigarette smoke-induced airway remodeling by upregulating SIRT1 signaling pathway.

Guan R, Wang J, Cai Z, Li Z, Wang L, Li Y, Xu J, Li D, Yao H, Liu W, Deng B, Lu W
Redox biology 2020 Jan;28:101356

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Human mesenchymal stem cells-derived conditioned medium inhibits hypoxia-induced death of neonatal porcine islets by inducing autophagy.

Xu Y, Tan M, Ma X, Li H, He X, Chen Z, Tan Y, Nie W, Rong P, Wang W
Xenotransplantation 2020 Jan;27(1):e12556

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LncRNA HOXA11-AS regulates calcium oxalate crystal-induced renal inflammation via miR-124-3p/MCP-1.

Li Y, Yan G, Zhang J, Chen W, Ding T, Yin Y, Li M, Zhu Y, Sun S, Yuan JH, Guo Z
Journal of cellular and molecular medicine 2020 Jan;24(1):238-249

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Arsenic influences spermatogenesis by disorganizing the elongation of spermatids in adult male mice.

Han Y, Liang C, Manthari RK, Yu Y, Gao Y, Liu Y, Jiang S, Tikka C, Wang J, Zhang J
Chemosphere 2020 Jan;238:124650

---

Endoplasmic reticulum stress regulates epithelial‑mesenchymal transition in human lens epithelial cells.

Zhou S, Yang J, Wang M, Zheng D, Liu Y
Molecular medicine reports 2020 Jan;21(1):173-180

---

Effects of oral florfenicol on intestinal structure, function and microbiota in mice.

Yun S, Guo Y, Yang L, Zhang X, Shen W, Wang Z, Wen S, Zhao D, Wu H, Chen J, Sun Y, Duan Z
Archives of microbiology 2020 Jan;202(1):161-169

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MicroRNA-138 inhibits tumor growth and enhances chemosensitivity in human cervical cancer by targeting H2AX.

Yuan M, Zhao S, Chen R, Wang G, Bie Y, Wu Q, Cheng J
Experimental and therapeutic medicine 2020 Jan;19(1):630-638

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REDD1 overexpression in oral squamous cell carcinoma may predict poor prognosis and correlates with high microvessel density.

Feng Y, Song K, Shang W, Chen L, Wang C, Pang B, Wang N
Oncology letters 2020 Jan;19(1):431-441

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USP12 translocation maintains interferon antiviral efficacy by inhibiting CBP acetyltransferase activity.

Liu J, Jin L, Chen X, Yuan Y, Zuo Y, Miao Y, Feng Q, Zhang H, Huang F, Guo T, Zhang L, Zhu L, Qian F, Zhu C, Zheng H
PLoS pathogens 2020 Jan;16(1):e1008215

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The novel thioredoxin reductase inhibitor A-Z2 triggers intrinsic apoptosis and shows efficacy in the treatment of acute myeloid leukemia.

Zhang D, Liu Y, Luo Z, Chen Y, Xu A, Liang Y, Wu B, Tong X, Liu X, Shen H, Liu L, Wei Y, Zhou H, Liu Y, Zhou F
Free radical biology & medicine 2020 Jan;146:275-286

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Osthole inhibits cell proliferation by regulating the TGF-β1/Smad/p38 signaling pathways in pulmonary arterial smooth muscle cells.

Yue Y, Li YQ, Fu S, Wu YT, Zhu L, Hua L, Lv JY, Li YL, Yang DL
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109640

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Tandem mass tag (TMT) proteomic analysis of fetal lungs revealed differential expression of tight junction proteins in a rat model of congenital diaphragmatic hernia.

Li X, Liu H, Yu W, Liu X, Liu C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109621

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Activation of CD137 signaling promotes neointimal formation by attenuating TET2 and transferrring from endothelial cell-derived exosomes to vascular smooth muscle cells.

Li B, Zang G, Zhong W, Chen R, Zhang Y, Yang P, Yan J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109593

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LncRNA GAS5 exacerbates renal tubular epithelial fibrosis by acting as a competing endogenous RNA of miR-96-5p.

Wang W, Jia YJ, Yang YL, Xue M, Zheng ZJ, Wang L, Xue YM
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109411

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Isolated Erythrocytosis Associated With 3 Novel Missense Mutations in the EGLN1 Gene.

Moore JA, Hubbi ME, Wang C, Wang Y, Luo W, Hofmann S, Rambally S
Journal of investigative medicine high impact case reports 2020 Jan-Dec;8:2324709620947256

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Acetyltransferase GCN5 regulates autophagy and lysosome biogenesis by targeting TFEB.

Wang Y, Huang Y, Liu J, Zhang J, Xu M, You Z, Peng C, Gong Z, Liu W
EMBO reports 2020 Jan 7;21(1):e48335

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5-(3,4,5-trimethoxybenzoyl)-4-methyl-2-(p-tolyl) imidazol (BZML) targets tubulin and DNA to induce anticancer activity and overcome multidrug resistance in colorectal cancer cells.

Bai Z, Liu X, Guan Q, Ding N, Wei Q, Tong B, Zhao M, Zhang W, Ma L
Chemico-biological interactions 2020 Jan 5;315:108886

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Resveratrol targets PD-L1 glycosylation and dimerization to enhance antitumor T-cell immunity.

Verdura S, Cuyàs E, Cortada E, Brunet J, Lopez-Bonet E, Martin-Castillo B, Bosch-Barrera J, Encinar JA, Menendez JA
Aging 2020 Jan 4;12(1):8-34

---

The tight junction protein TJP1 regulates the feeding-modulated hepatic circadian clock.

Liu Y, Zhang Y, Li T, Han J, Wang Y
Nature communications 2020 Jan 30;11(1):589

---

Porphyromonas gingivalis triggers inflammatory responses in periodontal ligament cells by succinate-succinate dehydrogenase-HIF-1α axis.

Su W, Shi J, Zhao Y, Yan F, Lei L, Li H
Biochemical and biophysical research communications 2020 Jan 29;522(1):184-190

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Alisol A-24-acetate promotes glucose uptake via activation of AMPK in C2C12 myotubes.

Chen JX, Li HY, Li TT, Fu WC, Du X, Liu CH, Zhang W
BMC complementary medicine and therapies 2020 Jan 29;20(1):22

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Schnurri-3 regulates BMP9-induced osteogenic differentiation and angiogenesis of human amniotic mesenchymal stem cells through Runx2 and VEGF.

Li Y, Liu Z, Tang Y, Feng W, Zhao C, Liao J, Zhang C, Chen H, Ren Y, Dong S, Liu Y, Hu N, Huang W
Cell death & disease 2020 Jan 29;11(1):72

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Calcium relieves fluoride-induced bone damage through the PI3K/AKT pathway.

Wang J, Xu H, Cheng X, Yang J, Yan Z, Ma H, Zhao Y, Ommati MM, Manthari RK, Wang J
Food & function 2020 Jan 29;11(1):1155-1164

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Graphene Oxide Promotes Cancer Metastasis through Associating with Plasma Membrane To Promote TGF-β Signaling-Dependent Epithelial-Mesenchymal Transition.

Zhu J, Li B, Xu M, Liu R, Xia T, Zhang Z, Xu Y, Liu S
ACS nano 2020 Jan 28;14(1):818-827

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GSPE alleviates renal fibrosis by inhibiting the activation of C3/ HMGB1/ TGF-β1 pathway.

Wang K, Wei H, Zhan J, Liang X, Zhang C, Liu Y, Xu G
Chemico-biological interactions 2020 Jan 25;316:108926

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An insertion mutation of ERBB2 enhances breast cancer cell growth and confers resistance to lapatinib through AKT signaling pathway.

Yang ZY, Yang L, Xu CW, Wang XJ, Lei L
Biology open 2020 Jan 24;9(1)

---

miR-485 suppresses inflammation and proliferation of mesangial cells in an in vitro model of diabetic nephropathy by targeting NOX5.

Wu J, Lu K, Zhu M, Xie X, Ding Y, Shao X, Chen Y, Liu J, Xu M, Xu Y, Zhou J, Shen X, Zhu C
Biochemical and biophysical research communications 2020 Jan 22;521(4):984-990

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FAM60A, increased by Helicobacter pylori, promotes proliferation and suppresses apoptosis of gastric cancer cells by targeting the PI3K/AKT pathway.

Yao X, Liu D, Zhou L, Xie Y, Li Y
Biochemical and biophysical research communications 2020 Jan 22;521(4):1003-1009

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A protective role of renalase in diabetic nephropathy.

Yin J, Liu X, Zhao T, Liang R, Wu R, Zhang F, Kong Y, Liu L, Xing T, Wang N, Zhao Q, Wang F
Clinical science (London, England : 1979) 2020 Jan 17;134(1):75-85

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The Nuclear Matrix Protein SAFB Cooperates with Major Satellite RNAs to Stabilize Heterochromatin Architecture Partially through Phase Separation.

Huo X, Ji L, Zhang Y, Lv P, Cao X, Wang Q, Yan Z, Dong S, Du D, Zhang F, Wei G, Liu Y, Wen B
Molecular cell 2020 Jan 16;77(2):368-383.e7

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Effects of a natural PTP1B inhibitor from Rhodomela confervoides on the amelioration of fatty acid-induced insulin resistance in hepatocytes and hyperglycaemia in STZ-induced diabetic rats.

Guo S, Wang L, Chen D, Jiang B
RSC advances 2020 Jan 16;10(6):3429-3437

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K562 cell-derived exosomes suppress the adhesive function of bone marrow mesenchymal stem cells via delivery of miR-711.

Jiang YH, Liu J, Lin J, Li SQ, Xu YM, Min QH, Zhong QH, Sun F, Li J, You XH, Liao KL, Qin TY, Zhao C, Huang B, Wang XZ
Biochemical and biophysical research communications 2020 Jan 15;521(3):584-589

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Fangchinoline derivatives induce cell cycle arrest and apoptosis in human leukemia cell lines via suppression of the PI3K/AKT and MAPK signaling pathway.

Yang J, Hu S, Wang C, Song J, Chen C, Fan Y, Ben-David Y, Pan W
European journal of medicinal chemistry 2020 Jan 15;186:111898

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Microglia P2X4R-BDNF signalling contributes to central sensitization in a recurrent nitroglycerin-induced chronic migraine model.

Long T, He W, Pan Q, Zhang S, Zhang D, Qin G, Chen L, Zhou J
The journal of headache and pain 2020 Jan 14;21(1):4

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DEF Cell-Derived Exosomal miR-148a-5p Promotes DTMUV Replication by Negative Regulating TLR3 Expression.

Guo H, Cheng A, Zhang X, Pan Y, Wang M, Huang J, Zhu D, Chen S, Liu M, Zhao X, Wu Y, Yang Q, Zhang S, Yu Y, Pan L, Tian B, Rehman MU, Chen X, Liu Y, Zhang L, Yin Z, Jing B, Jia R
Viruses 2020 Jan 14;12(1)

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RETRACTED: Endogenous production of C-C motif chemokine ligand 2 by nasopharyngeal carcinoma cells drives radioresistance-associated metastasis.

Guo SS, Liu R, Wen YF, Liu LT, Yuan L, Li YX, Li Y, Hao WW, Peng JY, Chen DN, Tang QN, Sun XS, Guo L, Mo HY, Qian CN, Zeng MS, Bei JX, Sun SY, Chen QY, Tang LQ, Mai HQ
Cancer letters 2020 Jan 1;468:27-40

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Schizandrin B Mitigates Rifampicin-Induced Liver Injury by Inhibiting Endoplasmic Reticulum Stress.

Cheng L, Yang Z, Sun Z, Zhang W, Ren Y, Wang M, Han X, Fei L, Zhao Y, Pan H, Xie J, Nie S
Biological & pharmaceutical bulletin 2020 Jan 1;43(1):145-152

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Regulation of the firing activity by PKA-PKC-Src family kinases in cultured neurons of hypothalamic arcuate nucleus.

Sun XD, Wang A, Ma P, Gong S, Tao J, Yu XM, Jiang X
Journal of neuroscience research 2020 Feb;98(2):384-403

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PITPNC1 fuels radioresistance of rectal cancer by inhibiting reactive oxygen species production.

Tan Y, Shao R, Li J, Huang H, Wang Y, Zhang M, Cao J, Zhang J, Bu J
Annals of translational medicine 2020 Feb;8(4):126

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Chronic toxicity of methamphetamine: Oxidative remodeling of pulmonary arteries.

Liang LY, Wang MM, Liu M, Zhao W, Wang X, Shi L, Zhu MJ, Zhao YL, Liu L, Maurya P, Wang Y
Toxicology in vitro : an international journal published in association with BIBRA 2020 Feb;62:104668

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Beta-Amyloid Increases the Expression Levels of Tid1 Responsible for Neuronal Cell Death and Amyloid Beta Production.

Zhou C, Taslima F, Abdelhamid M, Kim SW, Akatsu H, Michikawa M, Jung CG
Molecular neurobiology 2020 Feb;57(2):1099-1114

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Association between different levels of lipid metabolism‑related enzymes and fatty acid synthase in Wilms' tumor.

Wang X, Du G, Wu Y, Zhang Y, Guo F, Liu W, Wu R
International journal of oncology 2020 Feb;56(2):568-580

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BDNF-TrkB pathway mediates antidepressant-like roles of H(2) S in diabetic rats via promoting hippocampal autophagy.

Liu HY, Wei HJ, Wu L, Liu SM, Tang YY, Zou W, Wang CY, Zhang P, Tang XQ
Clinical and experimental pharmacology & physiology 2020 Feb;47(2):302-312

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Transcription factor RUNX2 regulates epithelial‑mesenchymal transition and progression in renal cell carcinomas.

Liu B, Liu J, Yu H, Wang C, Kong C
Oncology reports 2020 Feb;43(2):609-616

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Sirtuin 3 induces apoptosis and necroptosis by regulating mutant p53 expression in small‑cell lung cancer.

Tang X, Li Y, Liu L, Guo R, Zhang P, Zhang Y, Zhang Y, Zhao J, Su J, Sun L, Liu Y
Oncology reports 2020 Feb;43(2):591-600

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Visfatin Exerts Immunotherapeutic Effects in Lipopolysaccharide-Induced Acute Lung Injury in Murine Model.

Luo Y, Pang XX, Ansari AR, Wu XT, Li HZ, Zhang ZW, Song H
Inflammation 2020 Feb;43(1):109-122

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Lactobacillus johnsonii L531 ameliorates enteritis via elimination of damaged mitochondria and suppression of SQSTM1-dependent mitophagy in a Salmonella infantis model of piglet diarrhea.

Xia B, Yu J, He T, Liu X, Su J, Wang M, Wang J, Zhu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2821-2839

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Berberine inhibits proliferation and migration of colorectal cancer cells by downregulation of GRP78.

Gong C, Hu X, Xu Y, Yang J, Zong L, Wang C, Zhu J, Li Z, Lu D
Anti-cancer drugs 2020 Feb;31(2):141-149

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RhoB is regulated by hypoxia and modulates metastasis in breast cancer.

Ju JA, Godet I, DiGiacomo JW, Gilkes DM
Cancer reports (Hoboken, N.J.) 2020 Feb;3(1):e1164

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Polychlorinated biphenyl quinone promotes macrophage polarization to CD163(+) cells through Nrf2 signaling pathway.

Liu J, Yang B, Wang Y, Wu Y, Fan B, Zhu S, Song E, Song Y
Environmental pollution (Barking, Essex : 1987) 2020 Feb;257:113587

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LncRNA HRCEG, regulated by HDAC1, inhibits cells proliferation and epithelial-mesenchymal-transition in gastric cancer.

Wu S, Wu E, Wang D, Niu Y, Yue H, Zhang D, Luo J, Chen R
Cancer genetics 2020 Feb;241:25-33

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Mitochondrial respiratory chain damage and mitochondrial fusion disorder are involved in liver dysfunction of fluoride-induced mice.

Wang HW, Liu J, Wei SS, Zhao WP, Zhu SQ, Zhou BH
Chemosphere 2020 Feb;241:125099

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Effects of Starvation on Antioxidant-Related Signaling Molecules, Oxidative Stress, and Autophagy in Juvenile Chinese Perch Skeletal Muscle.

Wu P, Wang A, Cheng J, Chen L, Pan Y, Li H, Zhang Q, Zhang J, Chu W, Zhang J
Marine biotechnology (New York, N.Y.) 2020 Feb;22(1):81-93

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Involvement of neurotrophic signaling in doxorubicin-induced cardiotoxicity.

Liao D, Zhang C, Liu N, Cao L, Wang C, Feng Q, Yao D, Long M, Jiang P
Experimental and therapeutic medicine 2020 Feb;19(2):1129-1135

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1,3-Dicaffeoylquinic acid targeting 14-3-3 tau suppresses human breast cancer cell proliferation and metastasis through IL6/JAK2/PI3K pathway.

Zhou Y, Fu X, Guan Y, Gong M, He K, Huang B
Biochemical pharmacology 2020 Feb;172:113752

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Discovery of a first-in-class EZH2 selective degrader.

Ma A, Stratikopoulos E, Park KS, Wei J, Martin TC, Yang X, Schwarz M, Leshchenko V, Rialdi A, Dale B, Lagana A, Guccione E, Parekh S, Parsons R, Jin J
Nature chemical biology 2020 Feb;16(2):214-222

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PDE9 inhibition promotes proliferation of neural stem cells via cGMP-PKG pathway following oxygen-glucose deprivation/reoxygenation injury in vitro.

Huan X, Oumei C, Hongmei Q, Junxia Y, Xiaojiao M, Qingsong J
Neurochemistry international 2020 Feb;133:104630

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Predictive Value of Pin1 in Cervical Low-Grade Squamous Intraepithelial Lesions and Inhibition of Pin1 Exerts Potent Anticancer Activity against Human Cervical Cancer.

Guo YT, Lu Y, Jia YY, Qu HN, Qi D, Wang XQ, Song PY, Jin XS, Xu WH, Dong Y, Liang YY, Quan CS
Aging and disease 2020 Feb;11(1):44-59

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Ferrostatin-1 mitigates cognitive impairment of epileptic rats by inhibiting P38 MAPK activation.

Ye Q, Zeng C, Luo C, Wu Y
Epilepsy & behavior : E&B 2020 Feb;103(Pt A):106670

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The Combination of Fasting, Acute Resistance Exercise, and Protein Ingestion Led to Different Responses of Autophagy Markers in Gastrocnemius and Liver Samples.

Pinto AP, Vieira TS, Marafon BB, Batitucci G, Cabrera EMB, da Rocha AL, Kohama EB, Rodrigues KCC, de Moura LP, Pauli JR, Cintra DE, Ropelle ER, de Freitas EC, da Silva ASR
Nutrients 2020 Feb 28;12(3)

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MicroRNA-377-3p alleviates IL-1β-caused chondrocyte apoptosis and cartilage degradation in osteoarthritis in part by downregulating ITGA6.

Tu Y, Ma T, Wen T, Yang T, Xue L, Cai M, Wang F, Guan M, Xue H
Biochemical and biophysical research communications 2020 Feb 26;523(1):46-53

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RNA Binding Protein RNPC1 Suppresses the Stemness of Human Endometrial Cancer Cells via Stabilizing MST1/2 mRNA.

Wu X, Wang Y, Zhong W, Cheng H, Tian Z
Medical science monitor : international medical journal of experimental and clinical research 2020 Feb 23;26:e921389

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Targeting UBE4A Revives Viperin Protein in Epithelium to Enhance Host Antiviral Defense.

Yuan Y, Miao Y, Qian L, Zhang Y, Liu C, Liu J, Zuo Y, Feng Q, Guo T, Zhang L, Chen X, Jin L, Huang F, Zhang H, Zhang W, Li W, Xu G, Zheng H
Molecular cell 2020 Feb 20;77(4):734-747.e7

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Polyphyllin VII attenuated RANKL-induced osteoclast differentiation via inhibiting of TRAF6/c-Src/PI3K pathway and ROS production.

Zhou L, Song H, Zhang Y, Ren Z, Li M, Fu Q
BMC musculoskeletal disorders 2020 Feb 19;21(1):112

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GRWD1 promotes cell proliferation and migration in non-small cell lung cancer by activating the Notch pathway.

Wang Q, Ren H, Xu Y, Jiang J, Wudu M, Liu Z, Su H, Jiang X, Zhang Y, Zhang B, Qiu X
Experimental cell research 2020 Feb 15;387(2):111806

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Network Pharmacology-Based Prediction and Verification of Qingluo Tongbi Formula to Reduce Liver Toxicity of Tripterygium wilfordii via UGT2B7 in Endoplasmic Reticulum.

Li M, Wang J, Fu L, Lu Y, Xu J, Zhou L, Zhu H, Fang L, Feng Z, Xie T, Zhou X
Medical science monitor : international medical journal of experimental and clinical research 2020 Feb 15;26:e920376

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PRL/microRNA-183/IRS1 Pathway Regulates Milk Fat Metabolism in Cow Mammary Epithelial Cells.

Jiao P, Yuan Y, Zhang M, Sun Y, Wei C, Xie X, Zhang Y, Wang S, Chen Z, Wang X
Genes 2020 Feb 13;11(2)

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Sustained delivery of PlGF-2(123-144*)-fused BMP2-related peptide P28 from small intestinal submucosa/polylactic acid scaffold material for bone tissue regeneration.

Xiong Z, Cui W, Sun T, Teng Y, Qu Y, Yang L, Zhou J, Chen K, Yao S, Shao Z, Guo X
RSC advances 2020 Feb 13;10(12):7289-7300

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Doublecortin undergo nucleocytoplasmic transport via the RanGTPase signaling to promote glioma progression.

Ayanlaja AA, Ji G, Wang J, Gao Y, Cheng B, Kanwore K, Zhang L, Xiong Y, Kambey PA, Gao D
Cell communication and signaling : CCS 2020 Feb 12;18(1):24

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Curcumin Protects Human Trophoblast HTR8/SVneo Cells from H(2)O(2)-Induced Oxidative Stress by Activating Nrf2 Signaling Pathway.

Qi L, Jiang J, Zhang J, Zhang L, Wang T
Antioxidants (Basel, Switzerland) 2020 Feb 1;9(2)

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Protective effect of resveratrol on obesity-related osteoarthritis via alleviating JAK2/STAT3 signaling pathway is independent of SOCS3.

Jiang M, He J, Gu H, Yang Y, Huang Y, Xu X, Liu L
Toxicology and applied pharmacology 2020 Feb 1;388:114871

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PTP1B promotes macrophage activation by regulating the NF-κB pathway in alcoholic liver injury.

Yang L, Sun YY, Liu YR, Yin NN, Bu FT, Yu HX, Du XS, Li J, Huang C
Toxicology letters 2020 Feb 1;319:11-21

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Silencing of DsbA-L gene impairs the PPARγ agonist function of improving insulin resistance in a high-glucose cell model.

Zhou X, Li JQ, Wei LJ, He MZ, Jia J, Zhang JY, Wang SS, Feng L
Journal of Zhejiang University. Science. B 2020 Dec.;21(12):990-998

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SUMOylation of Pdia3 exacerbates proinsulin misfolding and ER stress in pancreatic beta cells.

Li N, Luo X, Yu Q, Yang P, Chen Z, Wang X, Jiang J, Xu J, Gong Q, Eizirik DL, Zhou Z, Zhao J, Xiong F, Zhang S, Wang CY
Journal of molecular medicine (Berlin, Germany) 2020 Dec;98(12):1795-1807

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LXA4 protects against hypoxic-ischemic damage in neonatal rats by reducing the inflammatory response via the IκB/NF-κB pathway.

Zhu JJ, Yu BY, Fu CC, He MZ, Zhu JH, Chen BW, Zheng YH, Chen SQ, Fu XQ, Li PJ, Lin ZL
International immunopharmacology 2020 Dec;89(Pt B):107095

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Annexin A3 upregulates the infiltrated neutrophil-lymphocyte ratio to remodel the immune microenvironment in hepatocellular carcinoma.

Zhu Q, Pan QZ, Zhong AL, Hu H, Zhao JJ, Tang Y, Hu WM, Li M, Weng DS, Chen MY, Ma G, Xia JC
International immunopharmacology 2020 Dec;89(Pt A):107139

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Angiopoietin-like protein 4 promotes very-low-density lipoprotein assembly and secretion in bovine hepatocytes in vitro.

Kong Y, Zhao C, Huang Y, Liu Y, Liu S, Guo Y, Li M, Xu T, Zhao B, Wang J
IUBMB life 2020 Dec;72(12):2710-2721

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Quercetin alleviates neonatal hypoxic-ischemic brain injury by inhibiting microglia-derived oxidative stress and TLR4-mediated inflammation.

Le K, Song Z, Deng J, Peng X, Zhang J, Wang L, Zhou L, Bi H, Liao Z, Feng Z
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2020 Dec;69(12):1201-1213

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Knockdown of eukaryotic translation initiation factor 5A2 enhances the therapeutic efficiency of doxorubicin in hepatocellular carcinoma cells by triggering lethal autophagy.

Tang Y, Chen K, Luan X, Zhang J, Liu R, Zheng X, Xie S, Ke H, Zhang X, Chen W
International journal of oncology 2020 Dec;57(6):1368-1380

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Nobiletin Ameliorates NLRP3 Inflammasome-Mediated Inflammation Through Promoting Autophagy via the AMPK Pathway.

Wang H, Guo Y, Qiao Y, Zhang J, Jiang P
Molecular neurobiology 2020 Dec;57(12):5056-5068

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An antiviral drug-resistant mutant of hepatitis B virus with high replication capacity in association with a large in-frame deletion in the preS1 region of viral surface gene.

Wang T, Qin Y, Zhang J, Li X, Tong S, Zhao W, Zhang J
Virus genes 2020 Dec;56(6):677-686

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Intratunical injection of human urine-derived stem cells derived exosomes prevents fibrosis and improves erectile function in a rat model of Peyronie's disease.

Yang Q, Chen W, Han D, Zhang C, Xie Y, Sun X, Liu G, Deng C
Andrologia 2020 Dec;52(11):e13831

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MMP7 damages the integrity of the renal tubule epithelium by activating MMP2/9 during ischemia-reperfusion injury.

Hu Q, Lan J, Liang W, Chen Y, Chen B, Liu Z, Xiong Y, Zhong Z, Wang Y, Ye Q
Journal of molecular histology 2020 Dec;51(6):685-700

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Down-Regulated CUEDC2 Increases GDNF Expression by Stabilizing CREB Through Reducing Its Ubiquitination in Glioma.

Liu XF, Tang CX, Zhang L, Tong SY, Wang Y, Abdulrahman AA, Ji GQ, Gao Y, Gao DS, Zhang BL
Neurochemical research 2020 Dec;45(12):2915-2925

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Aberrant expression of miRNA-192-5p contributes to N,N-dimethylformamide-induced hepatic apoptosis.

Zhang Z, Zhu W, Liu Z, Liu Y, Chang C, Jiang H, Li R, Xiao Y, Chen W, Hu Q, Wang Q
Journal of applied toxicology : JAT 2020 Dec;40(12):1683-1693

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Histone demethylase JHDM2A regulates H3K9 dimethylation in response to arsenic-induced DNA damage and repair in normal human liver cells.

Zhang AL, Tang SF, Yang Y, Li CZ, Ding XJ, Zhao H, Wang JH, Yang GH, Li J
Journal of applied toxicology : JAT 2020 Dec;40(12):1661-1672

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Inhibition of ACSL4 attenuates ferroptotic damage after pulmonary ischemia-reperfusion.

Xu Y, Li X, Cheng Y, Yang M, Wang R
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16262-16275

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PFOS-induced placental cell growth inhibition is partially mediated by lncRNA H19 through interacting with miR-19a and miR-19b.

Li J, Quan XJ, Chen G, Hong JW, Wang Q, Xu LL, Wang BH, Yu ZH, Yu HM
Chemosphere 2020 Dec;261:127640

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Molecular identification, tissue distribution and in vitro functional analysis of growth hormone and its receptors in red-spotted grouper (Epinephelus akaara).

Yuan X, Lin Y, Qin J, Zhang Y, Yang G, Cai R, Liao Z, Sun C, Li W
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2020 Dec;250:110488

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Inhibition of CACNA1H can alleviate endoplasmic reticulum stress and reduce myocardial cell apoptosis caused by myocardial infarction.

Wang MX, Liu X, Li JM, Liu L, Lu W, Chen GC
European review for medical and pharmacological sciences 2020 Dec;24(24):12887-12895

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FABP4 inhibitor attenuates inflammation and endoplasmic reticulum stress of islet in leptin receptor knockout rats.

Yao F, Jiang DD, Guo WH, Guo LS, Gao MM, Bai Y, Wang X, Zhang LS
European review for medical and pharmacological sciences 2020 Dec;24(24):12808-12820

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Polarization of ADAM17-driven EGFR signalling in electric field-guided collective migration of epidermal sheets.

Jia N, Liu J, Zhu G, Liang Y, Wang Y, Wang W, Chen Y, Yang J, Zhang W, Zhang J
Journal of cellular and molecular medicine 2020 Dec;24(23):14073-14085

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The proinflammatory cytokines IL-1β and TNF-α modulate corneal epithelial wound healing through p16(Ink4a) suppressing STAT3 activity.

Wang X, Zhang S, Dong M, Li Y, Zhou Q, Yang L
Journal of cellular physiology 2020 Dec;235(12):10081-10093

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miR-448-3p alleviates diabetic vascular dysfunction by inhibiting endothelial-mesenchymal transition through DPP-4 dysregulation.

Guan GY, Wei N, Song T, Zhao C, Sun Y, Pan RX, Zhang LL, Xu YY, Dai YM, Han H
Journal of cellular physiology 2020 Dec;235(12):10024-10036

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Inhibition of p38 MAPK regulates epileptic severity by decreasing expression levels of A1R and ENT1.

Zhou X, Chen Q, Huang H, Zhang J, Wang J, Chen Y, Peng Y, Zhang H, Zeng J, Feng Z, Xu Z
Molecular medicine reports 2020 Dec;22(6):5348-5357

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Effect of TFAM on ATP content in tachypacing primary cultured cardiomyocytes and atrial fibrillation patients.

Liu Y, Zhao Y, Tang R, Jiang X, Wang Y, Gu T
Molecular medicine reports 2020 Dec;22(6):5105-5112

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IGFBP‑rP1‑silencing promotes hypoxia‑induced angiogenic potential of choroidal endothelial cells via the RAF/MEK/ERK signaling pathway.

Zhu S, Wang H, Zhang Z, Ma M, Zheng Z, Xu X, Sun T
Molecular medicine reports 2020 Dec;22(6):4837-4847

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Pseudolaric acid B induces apoptosis in human rhabdomyosarcoma RD cells.

Liu C, Wang F, Wang B, Wu T, Wang Y, Huo W, Zhang S, Su Y, Liu J, Liu Y, Yu J
Oncology letters 2020 Dec;20(6):358

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A Combination of BRD4 and HDAC3 Inhibitors Synergistically Suppresses Glioma Stem Cell Growth by Blocking GLI1/IL6/STAT3 Signaling Axis.

Wang Q, Jia S, Wang D, Chen X, Kalvakolanu DV, Zheng H, Wei X, Wen N, Liang H, Guo B, Zhang L
Molecular cancer therapeutics 2020 Dec;19(12):2542-2553

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Resveratrol improves meat quality, muscular antioxidant capacity, lipid metabolism and fiber type composition of intrauterine growth retarded pigs.

Cheng K, Yu C, Li Z, Li S, Yan E, Song Z, Zhang H, Zhang L, Wang T
Meat science 2020 Dec;170:108237

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Polymethoxyflavones from citrus inhibited gastric cancer cell proliferation through inducing apoptosis by upregulating RARβ, both in vitro and in vivo.

Wang Y, Chen Y, Zhang H, Chen J, Cao J, Chen Q, Li X, Sun C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Dec;146:111811

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Cannabinoid receptor subtype influence on neuritogenesis in human SH-SY5Y cells.

Lyons EL, Leone-Kabler S, Kovach AL, Thomas BF, Howlett AC
Molecular and cellular neurosciences 2020 Dec;109:103566

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Andrographolide exerts anti-inflammatory effects in Mycobacterium tuberculosis-infected macrophages by regulating the Notch1/Akt/NF-κB axis.

He W, Sun J, Zhang Q, Li Y, Fu Y, Zheng Y, Jiang X
Journal of leukocyte biology 2020 Dec;108(6):1747-1764

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Structural and Functional Characterization of Host FHL1 Protein Interaction with Hypervariable Domain of Chikungunya Virus nsP3 Protein.

Lukash T, Agback T, Dominguez F, Shiliaev N, Meshram C, Frolova EI, Agback P, Frolov I
Journal of virology 2020 Dec 9;95(1)

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β-Elemene enhances radiosensitivity in non-small-cell lung cancer by inhibiting epithelial-mesenchymal transition and cancer stem cell traits via Prx-1/NF-kB/iNOS signaling pathway.

Zou K, Li Z, Zhang Y, Mu L, Chen M, Wang R, Deng W, Zou L, Liu J
Aging 2020 Dec 9;13(2):2575-2592

---

Condensation of Rubisco into a proto-pyrenoid in higher plant chloroplasts.

Atkinson N, Mao Y, Chan KX, McCormick AJ
Nature communications 2020 Dec 9;11(1):6303

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Exploration of the Effects of Substrate Stiffness on Biological Responses of Neural Cells and Their Mechanisms.

Zhang C, Tan Y, Feng J, Huang C, Liu B, Fan Z, Xu B, Lu T
ACS omega 2020 Dec 8;5(48):31115-31125

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circ_2858 Helps Blood-Brain Barrier Disruption by Increasing VEGFA via Sponging miR-93-5p during Escherichia coli Meningitis.

Yang R, Chen J, Xu B, Yang B, Fu J, Xiao S, Tan C, Chen H, Wang X
Molecular therapy. Nucleic acids 2020 Dec 4;22:708-721

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Metabotropic glutamate receptor 5 regulates synaptic plasticity in a chronic migraine rat model through the PKC/NR2B signal.

Niu Y, Zeng X, Zhao L, Zhou Y, Qin G, Zhang D, Fu Q, Zhou J, Chen L
The journal of headache and pain 2020 Dec 4;21(1):139

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein inhibits type I and III interferon production by targeting RIG-I/MDA-5 signaling.

Zheng Y, Zhuang MW, Han L, Zhang J, Nan ML, Zhan P, Kang D, Liu X, Gao C, Wang PH
Signal transduction and targeted therapy 2020 Dec 28;5(1):299

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TRIM24 promotes stemness and invasiveness of glioblastoma cells via activating Sox2 expression.

Zhang LH, Yin YH, Chen HZ, Feng SY, Liu JL, Chen L, Fu WL, Sun GC, Yu XG, Xu DG
Neuro-oncology 2020 Dec 18;22(12):1797-1808

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RIPK1 Distinctly Regulates Yersinia-Induced Inflammatory Cell Death, PANoptosis.

Malireddi RKS, Kesavardhana S, Karki R, Kancharana B, Burton AR, Kanneganti TD
ImmunoHorizons 2020 Dec 11;4(12):789-796

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Ubiquitination of RIPK1 regulates its activation mediated by TNFR1 and TLRs signaling in distinct manners.

Li X, Zhang M, Huang X, Liang W, Li G, Lu X, Li Y, Pan H, Shi L, Zhu H, Qian L, Shan B, Yuan J
Nature communications 2020 Dec 11;11(1):6364

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Exploring the mechanism of cisplatin resistance by transcriptome sequencing and reversing the chemoresistance by autophagy inhibition in small cell lung cancer.

Ma K, Li S, Huo X, Guo M, Du X, Li C, Liu X, Lv J, Chen Z
Biochemical and biophysical research communications 2020 Dec 10;533(3):474-480

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Podocyte-derived extracellular vesicles mediate renal proximal tubule cells dedifferentiation via microRNA-221 in diabetic nephropathy.

Su H, Qiao J, Hu J, Li Y, Lin J, Yu Q, Zhen J, Ma Q, Wang Q, Lv Z, Wang R
Molecular and cellular endocrinology 2020 Dec 1;518:111034

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PhospholipaseCγ1/calcium-dependent membranous localization of Gsdmd-N drives endothelial pyroptosis, contributing to lipopolysaccharide-induced fatal outcome.

Liu H, Tang D, Zhou X, Yang X, Chen AF
American journal of physiology. Heart and circulatory physiology 2020 Dec 1;319(6):H1482-H1495

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Effects of taraxasterol against ethanol and high-fat diet-induced liver injury by regulating TLR4/MyD88/NF-κB and Nrf2/HO-1 signaling pathways.

Li Z, Lian Y, Wei R, Jin L, Cao H, Zhao T, Ma X, Zhong M, Gao Y, Zhang K
Life sciences 2020 Dec 1;262:118546

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NPY stimulates cholesterol synthesis acutely by activating the SREBP2-HMGCR pathway through the Y1 and Y5 receptors in murine hepatocytes.

Chen F, Zhou Y, Yang K, Shen M, Wang Y
Life sciences 2020 Dec 1;262:118478

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Prostaglandin I2 mediates weak vasodilatation in human placental microvessels.

Feng X, Zhang Y, Zhang Y, Yang X, Man D, Lu L, Xu T, Liu Y, Yang C, Li H, Qi L, Su H, Zhou X, Xu Z
Biology of reproduction 2020 Dec 1;103(6):1229-1237

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HOTAIR promotes paclitaxel resistance by regulating CHEK1 in ovarian cancer.

Jiang J, Wang S, Wang Z, Cai J, Han L, Xie L, Han Q, Wang W, Zhang Y, He X, Yang C
Cancer chemotherapy and pharmacology 2020 Aug;86(2):295-305

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Ginsenoside Rk3 alleviated DSS-induced ulcerative colitis by protecting colon barrier and inhibiting NLRP3 inflammasome pathway.

Tian M, Ma P, Zhang Y, Mi Y, Fan D
International immunopharmacology 2020 Aug;85:106645

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Metformin inhibits extracellular matrix accumulation, inflammation and proliferation of mesangial cells in diabetic nephropathy by regulating H19/miR-143-3p/TGF-β1 axis.

Xu J, Xiang P, Liu L, Sun J, Ye S
The Journal of pharmacy and pharmacology 2020 Aug;72(8):1101-1109

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GOLPH3 Regulates Exosome miRNA Secretion in Glioma Cells.

Hu P, Wang K, Zhou D, Wang L, Zhao M, Wang W, Zhang Y, Liu Y, Yu R, Zhou X
Journal of molecular neuroscience : MN 2020 Aug;70(8):1257-1266

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Metabolomic profiling reveals similar cytotoxic effects and protective functions of quercetin during deoxynivalenol- and 15-acetyl deoxynivalenol-induced cell apoptosis.

Yang YX, Yu S, Jia BX, Liu N, Wu A
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104838

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All-Trans Retinoic Acid Exerts Neuroprotective Effects in Amyotrophic Lateral Sclerosis-Like Tg (SOD1*G93A)1Gur Mice.

Zhu Y, Liu Y, Yang F, Chen W, Jiang J, He P, Jiang S, Li M, Xu R
Molecular neurobiology 2020 Aug;57(8):3603-3615

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Exopolysaccharide from Cryptococcus heimaeyensis S20 induces autophagic cell death in non-small cell lung cancer cells via ROS/p38 and ROS/ERK signalling.

Hao Y, Huang Y, Chen J, Li J, Yuan Y, Wang M, Han L, Xin X, Wang H, Lin D, Peng F, Yu F, Zheng C, Shen C
Cell proliferation 2020 Aug;53(8):e12869

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Role of Zinc Sulphate in Immune Regulation in Artemisia annua Pollen-challenged P815 Mastocytoma Cells.

Yang FX, Hou L, Wen WL, Shen XL, Feng NY, Ma RX, Yin S
Immunological investigations 2020 Aug;49(6):622-631

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Exogenous spermine attenuates myocardial fibrosis in diabetic cardiomyopathy by inhibiting endoplasmic reticulum stress and the canonical Wnt signaling pathway.

Hu J, Lu X, Zhang X, Shao X, Wang Y, Chen J, Zhao B, Li S, Xu C, Wei C
Cell biology international 2020 Aug;44(8):1660-1670

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Setosphapyrone C and D accelerate macrophages cholesterol efflux by promoting LXRα/ABCA1 pathway.

Li T, Yin J, Ji Y, Lin P, Li Y, Yang Z, Hu S, Wang J, Zhang B, Koshti S, Wang J, Ji C, Guo S
Archives of pharmacal research 2020 Aug;43(8):788-797

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Thymidine phosphorylase promotes angiogenesis and tumour growth in intrahepatic cholangiocarcinoma.

Li S, Yang H, Li K, Fan G, Deng L, Xu C
Cell biochemistry and function 2020 Aug;38(6):743-752

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Downregulation of miR-140-5p affects the pathogenesis of HSCR by targeting EGR2.

Du G, Wang X, Wu Y, Zhang Y, Liu W, Wu R
Pediatric surgery international 2020 Aug;36(8):883-890

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Inhibition of the facilitative sugar transporters (GLUTs) by tea extracts and catechins.

Ni D, Ai Z, Munoz-Sandoval D, Suresh R, Ellis PR, Yuqiong C, Sharp PA, Butterworth PJ, Yu Z, Corpe CP
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Aug;34(8):9995-10010

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Lnc00462717 regulates the permeability of the blood-brain tumor barrier through interaction with PTBP1 to inhibit the miR-186-5p/Occludin signaling pathway.

Zhang C, Zhang X, Wang J, Di F, Xue Y, Lin X, Zhang Y, Zhang H, Zhang Z, Gu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Aug;34(8):9941-9958

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USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylation.

Rusilowicz-Jones EV, Jardine J, Kallinos A, Pinto-Fernandez A, Guenther F, Giurrandino M, Barone FG, McCarron K, Burke CJ, Murad A, Martinez A, Marcassa E, Gersch M, Buckmelter AJ, Kayser-Bricker KJ, Lamoliatte F, Gajbhiye A, Davis S, Scott HC, Murphy E, England K, Mortiboys H, Komander D, Trost M, Kessler BM, Ioannidis S, Ahlijanian MK, Urbé S, Clague MJ
Life science alliance 2020 Aug;3(8)

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Pseudorabies virus infection inhibits stress granules formation via dephosphorylating eIF2α.

Xu S, Chen D, Chen D, Hu Q, Zhou L, Ge X, Han J, Guo X, Yang H
Veterinary microbiology 2020 Aug;247:108786

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Protective effect of exogenous hydrogen sulfide on diaphragm muscle fibrosis in streptozotocin-induced diabetic rats.

Yang R, Jia Q, Li Y, Mehmood S
Experimental biology and medicine (Maywood, N.J.) 2020 Aug;245(14):1280-1289

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Cell cycle exit during bortezomib-induced osteogenic differentiation of mesenchymal stem cells was mediated by Xbp1s-upregulated p21(Cip1) and p27(Kip1).

Zhang D, Fan R, Lei L, Lei L, Wang Y, Lv N, Chen P, Williamson RA, Wang B, Hu J
Journal of cellular and molecular medicine 2020 Aug;24(16):9428-9438

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Salvianic acid A alleviates chronic alcoholic liver disease by inhibiting HMGB1 translocation via down-regulating BRD4.

Lan Y, Yan R, Shan W, Chu J, Sun R, Wang R, Zhao Y, Wang Z, Zhang N, Yao J
Journal of cellular and molecular medicine 2020 Aug;24(15):8518-8531

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Septin4 regulates endoplasmic reticulum stress and apoptosis in melatonin‑induced osteoblasts.

Tao L, Zhao S, Tao Z, Wen K, Zhou S, Da W, Zhu Y
Molecular medicine reports 2020 Aug;22(2):1179-1186

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Overexpression of negative regulator of ubiquitin-like proteins 1 (NUB1) inhibits proliferation and invasion of gastric cancer cells through upregulation of p27Kip1 and inhibition of epithelial-mesenchymal transition.

Zhang D, Wu P, Zhang Z, An W, Zhang C, Pan S, Tan Y, Xu H
Pathology, research and practice 2020 Aug;216(8):153002

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Overexpression of B7-H4 promotes renal cell carcinoma progression by recruiting tumor-associated neutrophils via upregulation of CXCL8.

Li A, Zhang N, Zhao Z, Chen Y, Zhang L
Oncology letters 2020 Aug;20(2):1535-1544

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Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated β-catenin pathway and EMT in colorectal cancer.

Liu D, Zhang H, Cui M, Chen C, Feng Y
Cell cycle (Georgetown, Tex.) 2020 Aug;19(15):1917-1927

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Catalase is required for peroxisome maintenance during adipogenesis.

Nitta Y, Muraoka-Hirayama S, Sakurai K
Biochimica et biophysica acta. Molecular and cell biology of lipids 2020 Aug;1865(8):158726

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Targeting G6PD reverses paclitaxel resistance in ovarian cancer by suppressing GSTP1.

Feng Q, Li X, Sun W, Sun M, Li Z, Sheng H, Xie F, Zhang S, Shan C
Biochemical pharmacology 2020 Aug;178:114092

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Sarcopenia is attenuated by TRB3 knockout in aging mice via the alleviation of atrophy and fibrosis of skeletal muscles.

Shang GK, Han L, Wang ZH, Liu YP, Yan SB, Sai WW, Wang D, Li YH, Zhang W, Zhong M
Journal of cachexia, sarcopenia and muscle 2020 Aug;11(4):1104-1120

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Localization of ZIP14 and ZIP8 in HIBCPP Cells.

Morgan SE, Schroten H, Ishikawa H, Zhao N
Brain sciences 2020 Aug 8;10(8)

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Reelin Promotes Cisplatin Resistance by Induction of Epithelial-Mesenchymal Transition via p38/GSK3β/Snail Signaling in Non-Small Cell Lung Cancer.

Li JM, Yang F, Li J, Yuan WQ, Wang H, Luo YQ
Medical science monitor : international medical journal of experimental and clinical research 2020 Aug 7;26:e925298

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STIM1-mediated calcium influx controls antifungal immunity and the metabolic function of non-pathogenic Th17 cells.

Kahlfuss S, Kaufmann U, Concepcion AR, Noyer L, Raphael D, Vaeth M, Yang J, Pancholi P, Maus M, Muller J, Kozhaya L, Khodadadi-Jamayran A, Sun Z, Shaw P, Unutmaz D, Stathopulos PB, Feist C, Cameron SB, Turvey SE, Feske S
EMBO molecular medicine 2020 Aug 7;12(8):e11592

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Selective Translation of Cell Fate Regulators Mediates Tolerance to Broad Oncogenic Stress.

Cai EY, Kufeld MN, Schuster S, Arora S, Larkin M, Germanos AA, Hsieh AC, Beronja S
Cell stem cell 2020 Aug 6;27(2):270-283.e7

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Development of a Cationic Amphiphilic Helical Peptidomimetic (B18L) As A Novel Anti-Cancer Drug Lead.

Lyu Y, Kopcho S, Alvarez FA, Okeoma BC, Okeoma CM
Cancers 2020 Aug 28;12(9)

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Hippuric Acid Promotes Renal Fibrosis by Disrupting Redox Homeostasis via Facilitation of NRF2-KEAP1-CUL3 Interactions in Chronic Kidney Disease.

Sun B, Wang X, Liu X, Wang L, Ren F, Wang X, Leng X
Antioxidants (Basel, Switzerland) 2020 Aug 25;9(9)

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Cotargeting of Mitochondrial Complex I and Bcl-2 Shows Antileukemic Activity against Acute Myeloid Leukemia Cells Reliant on Oxidative Phosphorylation.

Liu F, Kalpage HA, Wang D, Edwards H, Hüttemann M, Ma J, Su Y, Carter J, Li X, Polin L, Kushner J, Dzinic SH, White K, Wang G, Taub JW, Ge Y
Cancers 2020 Aug 24;12(9)

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α-Mangostin, a Dietary Xanthone, Exerts Protective Effects on Cisplatin-Induced Renal Injury via PI3K/Akt and JNK Signaling Pathways in HEK293 Cells.

Li Q, Yan XT, Zhao LC, Ren S, He YF, Liu WC, Wang Z, Li XD, Jiang S, Li W
ACS omega 2020 Aug 18;5(32):19960-19967

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Tetrandrine enhances glucocorticoid receptor translocation possibly via inhibition of P-glycoprotein in daunorubicin-resistant human T lymphoblastoid leukemia cells.

Xu W, Wang X, Chen S, Wu H, Tanaka S, Onda K, Sugiyama K, Yamada H, Hirano T
European journal of pharmacology 2020 Aug 15;881:173232

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Bcl2 inhibitor ABT737 reverses the Warburg effect via the Sirt3-HIF1α axis to promote oxidative stress-induced apoptosis in ovarian cancer cells.

Dong D, Dong Y, Fu J, Lu S, Yuan C, Xia M, Sun L
Life sciences 2020 Aug 15;255:117846

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Lactobacillus johnsonii L531 Ameliorates Escherichia coli-Induced Cell Damage via Inhibiting NLRP3 Inflammasome Activity and Promoting ATG5/ATG16L1-Mediated Autophagy in Porcine Mammary Epithelial Cells.

Zou YJ, Xu JJ, Wang X, Zhu YH, Wu Q, Wang JF
Veterinary sciences 2020 Aug 14;7(3)

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Plakoglobin is involved in cytoskeletal rearrangement of podocytes under the regulation of UCH-L1.

Fang Y, Li F, Qi C, Mao X, Xu Y, Zhao Z, Wu H, Zhang Z
Biochemical and biophysical research communications 2020 Aug 13;529(1):112-118

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Flavagline synthetic derivative induces senescence in glioblastoma cancer cells without being toxic to healthy astrocytes.

Harmouch E, Seitlinger J, Chaddad H, Ubeaud-Sequier G, Barths J, Saidu S, Désaubry L, Grandemange S, Massfelder T, Fuhrmann G, Fioretti F, Dontenwill M, Benkirane-Jessel N, Idoux-Gillet Y
Scientific reports 2020 Aug 13;10(1):13750

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Acetylation of Cytidine Residues Boosts HIV-1 Gene Expression by Increasing Viral RNA Stability.

Tsai K, Jaguva Vasudevan AA, Martinez Campos C, Emery A, Swanstrom R, Cullen BR
Cell host & microbe 2020 Aug 12;28(2):306-312.e6

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Cultivation of Hair Matrix Cells from Cashmere Goat Skins and Exemplified Applications.

Ma S, Wang L, Zong B, Wang Y, Wang X, Shi Y, Yang Y, Chen Y
Animals : an open access journal from MDPI 2020 Aug 12;10(8)

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The Small Molecule P7C3-A20 Exerts Neuroprotective Effects in a Hypoxic-ischemic Encephalopathy Model via Activation of PI3K/AKT/GSK3β Signaling.

Bai J, Zeng S, Zhu J, Fu C, He M, Zhu J, Chen S, Fu X, Li P, Lin Z
Neuroscience 2020 Aug 10;441:197-208

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TMT-based proteomics analysis reveals the protective effects of Xuefu Zhuyu decoction in a rat model of traumatic brain injury.

Zhou D, Liu J, Hang Y, Li T, Li P, Guo S, Liu T, Xia Z, Wang Y
Journal of ethnopharmacology 2020 Aug 10;258:112826

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Lignans from Schisandra chinensis ameliorate alcohol and CCl(4)-induced long-term liver injury and reduce hepatocellular degeneration via blocking ETBR.

Xu JB, Gao GC, Yuan MJ, Huang X, Zhou HY, Zhang Y, Zheng YX, Wu Z, Feng JM, Wu JM
Journal of ethnopharmacology 2020 Aug 10;258:112813

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Role of ion channels in chronic intermittent hypoxia-induced atrial remodeling in rats.

Zhang K, Ma Z, Song C, Duan X, Yang Y, Li G
Life sciences 2020 Aug 1;254:117797

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TLR4 knockout upregulates the expression of Mfn2 and PGC-1α in a high-fat diet and ischemia-reperfusion mice model of liver injury.

Zhang C, Jia Y, Liu B, Wang G, Zhang Y
Life sciences 2020 Aug 1;254:117762

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Comparative analysis of two brine shrimps revealed differential expression pattern and functional characterization of CK2α under bacterial stimulation from different geographical distribution.

Wang Z, Hou Q, Wan K, Zhang R, Dong L, Zhang D, Yin H
Fish & shellfish immunology 2020 Apr;99:631-640

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Fangjihuangqi Decoction inhibits MDA-MB-231 cell invasion in vitro and decreases tumor growth and metastasis in triple-negative breast cancer xenografts tumor zebrafish model.

Guo Y, Fan Y, Pei X
Cancer medicine 2020 Apr;9(7):2564-2578

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Berberine combined with cyclosporine A alleviates acute graft-versus-host disease in murine models.

Wang M, Zhang J, Zhao H, Wan D, Jiang Z
International immunopharmacology 2020 Apr;81:106205

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Long non-coding RNA LOC100133669 promotes cell proliferation in oesophageal squamous cell carcinoma.

Guan Z, Wang Y, Wang Y, Liu X, Wang Y, Zhang W, Chi X, Dong Y, Liu X, Shao S, Zhan Q
Cell proliferation 2020 Apr;53(4):e12750

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Retinoid X receptor α (RXRα)-mediated erythroid-2-related factor-2 (NRF2) inactivation contributes to N,N-dimethylformamide (DMF)-induced oxidative stress in HL-7702 and HuH6 cells.

Jiang H, Li R, Zhang Z, Chang C, Liu Y, Liu Z, He Q, Wang Q
Journal of applied toxicology : JAT 2020 Apr;40(4):470-482

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The Potential Role of PKA/CREB Signaling Pathway Concerned with Gastrodin Administration on Methamphetamine-Induced Conditioned Place Preference Rats and SH-SY5Y Cell Line.

Yang GM, Li L, Xue FL, Ma CL, Zeng XF, Zhao YN, Zhang DX, Yu Y, Yan QW, Zhou YQ, Hong SJ, Li LH
Neurotoxicity research 2020 Apr;37(4):926-935

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Virus analog decreases estradiol secretion in FSH-treated human ovarian granulosa cells.

Fang Y, Wang B, Lyu S, Zhang K, Cheng Q, Zhu Y
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2020 Apr;36(4):346-350

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The deletion of mutant SOD1 via CRISPR/Cas9/sgRNA prolongs survival in an amyotrophic lateral sclerosis mouse model.

Duan W, Guo M, Yi L, Liu Y, Li Z, Ma Y, Zhang G, Liu Y, Bu H, Song X, Li C
Gene therapy 2020 Apr;27(3-4):157-169

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MiR-129-5p protects against myocardial ischemia-reperfusion injury via targeting HMGB1.

Chen ZX, He D, Mo QW, Xie LP, Liang JR, Liu L, Fu WJ
European review for medical and pharmacological sciences 2020 Apr;24(8):4440-4450

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Targeting STAT3 enhances NDV-induced immunogenic cell death in prostate cancer cells.

Wang X, Shao X, Gu L, Jiang K, Wang S, Chen J, Fang J, Guo X, Yuan M, Shi J, Ding C, Meng S, Xu Q
Journal of cellular and molecular medicine 2020 Apr;24(7):4286-4297

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GLL398, an oral selective estrogen receptor degrader (SERD), blocks tumor growth in xenograft breast cancer models.

Guo S, Zhang C, Mottamal M, Hossain A, Liu J, Wang G
Breast cancer research and treatment 2020 Apr;180(2):359-368

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IL-29 promoted obesity-induced inflammation and insulin resistance.

Lin TY, Chiu CJ, Kuan CH, Chen FH, Shen YC, Wu CH, Hsu YH
Cellular & molecular immunology 2020 Apr;17(4):369-379

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NEK2 induces autophagy-mediated bortezomib resistance by stabilizing Beclin-1 in multiple myeloma.

Xia J, He Y, Meng B, Chen S, Zhang J, Wu X, Zhu Y, Shen Y, Feng X, Guan Y, Kuang C, Guo J, Lei Q, Wu Y, An G, Li G, Qiu L, Zhan F, Zhou W
Molecular oncology 2020 Apr;14(4):763-778

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A novel Sprouty4-ERK1/2-Wnt/β-catenin regulatory loop in marrow stromal progenitor cells controls osteogenic and adipogenic differentiation.

Tian L, Xiao H, Li M, Wu X, Xie Y, Zhou J, Zhang X, Wang B
Metabolism: clinical and experimental 2020 Apr;105:154189

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Myxovirus resistance (Mx) gene and its differential expression regulated by three type I and two type II IFNs in mandarin fish, Siniperca chuatsi.

Li L, Chen SN, Laghari ZA, Huo HJ, Hou J, Huang L, Li N, Nie P
Developmental and comparative immunology 2020 Apr;105:103604

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AKT but not MYC promotes reactive oxygen species-mediated cell death in oxidative culture.

Zheng D, Sussman JH, Jeon MP, Parrish ST, MacMullan MA, Delfarah A, Graham NA
Journal of cell science 2020 Apr 9;133(7)

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p53-mediated control of aspartate-asparagine homeostasis dictates LKB1 activity and modulates cell survival.

Deng L, Yao P, Li L, Ji F, Zhao S, Xu C, Lan X, Jiang P
Nature communications 2020 Apr 9;11(1):1755

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A Combination of Formic Acid and Monolaurin Attenuates Enterotoxigenic Escherichia coli Induced Intestinal Inflammation in Piglets by Inhibiting the NF-κB/MAPK Pathways with Modulation of Gut Microbiota.

Ren C, Wang Y, Lin X, Song H, Zhou Q, Xu W, Shi K, Chen J, Song J, Chen F, Zhang S, Guan W
Journal of agricultural and food chemistry 2020 Apr 8;68(14):4155-4165

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Synergistic Neuroprotective Effect of Endogenously-Produced Hydroxytyrosol and Synaptic Vesicle Proteins on Pheochromocytoma Cell Line Against Salsolinol.

Manzoor R, Rasool A, Ahmed M, Kaleem U, Duru LN, Ma H, Deng Y
Molecules (Basel, Switzerland) 2020 Apr 8;25(7)

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Interaction between PHB2 and Enterovirus A71 VP1 Induces Autophagy and Affects EV-A71 Infection.

Su W, Huang S, Zhu H, Zhang B, Wu X
Viruses 2020 Apr 8;12(4)

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Anti-neuroinflammatory effects of dimethylaminomylide (DMAMCL, i.e., ACT001) are associated with attenuating the NLRP3 inflammasome in MPTP-induced Parkinson disease in mice.

Liu Q, Guo X, Huang Z, He Q, Zhu D, Zhang S, Peng Z, Che Y, Feng X
Behavioural brain research 2020 Apr 6;383:112539

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MicroRNA-574-5p in gastric cancer cells promotes angiogenesis by targeting protein tyrosine phosphatase non-receptor type 3 (PTPN3).

Zhang S, Zhang R, Xu R, Shang J, He H, Yang Q
Gene 2020 Apr 5;733:144383

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Effect of fluoride on osteocyte-driven osteoclastic differentiation.

Jiang N, Guo F, Xu W, Zhang Z, Jin H, Shi L, Zhang X, Gao J, Xu H
Toxicology 2020 Apr 30;436:152429

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Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense.

Zheng M, Karki R, Vogel P, Kanneganti TD
Cell 2020 Apr 30;181(3):674-687.e13

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Decreased ZNF750 promotes angiogenesis in a paracrine manner via activating DANCR/miR-4707-3p/FOXC2 axis in esophageal squamous cell carcinoma.

Bi Y, Guo S, Xu X, Kong P, Cui H, Yan T, Ma Y, Cheng Y, Chen Y, Liu X, Zhang L, Cheng C, Xu E, Qian Y, Yang J, Song B, Li H, Wang F, Hu X, Liu X, Niu X, Zhai Y, Liu J, Li Y, Cheng X, Cui Y
Cell death & disease 2020 Apr 27;11(4):296

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Cold atmospheric plasma induces GSDME-dependent pyroptotic signaling pathway via ROS generation in tumor cells.

Yang X, Chen G, Yu KN, Yang M, Peng S, Ma J, Qin F, Cao W, Cui S, Nie L, Han W
Cell death & disease 2020 Apr 27;11(4):295

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4β-Hydroxywithanolide E from Goldenberry (Whole Fruits of Physalis peruviana L.) as a Promising Agent against Chronic Obstructive Pulmonary Disease.

Yang WJ, Chen XM, Wang SQ, Hu HX, Cheng XP, Xu LT, Ren DM, Wang XN, Zhao BB, Lou HX, Shen T
Journal of natural products 2020 Apr 24;83(4):1217-1228

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HIF-1β Positively Regulates NF-κB Activity via Direct Control of TRAF6.

D'Ignazio L, Shakir D, Batie M, Muller HA, Rocha S
International journal of molecular sciences 2020 Apr 24;21(8)

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Maternal curcumin supplementation ameliorates placental function and fetal growth in mice with intrauterine growth retardation†.

Qi L, Jiang J, Zhang J, Zhang L, Wang T
Biology of reproduction 2020 Apr 24;102(5):1090-1101

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Pathogenic Variants in CEP85L Cause Sporadic and Familial Posterior Predominant Lissencephaly.

Tsai MH, Muir AM, Wang WJ, Kang YN, Yang KC, Chao NH, Wu MF, Chang YC, Porter BE, Jansen LA, Sebire G, Deconinck N, Fan WL, Su SC, Chung WH, Almanza Fuerte EP, Mehaffey MG, University of Washington Center for Mendelian Genomics, Ng CC, Chan CK, Lim KS, Leventer RJ, Lockhart PJ, Riney K, Damiano JA, Hildebrand MS, Mirzaa GM, Dobyns WB, Berkovic SF, Scheffer IE, Tsai JW, Mefford HC
Neuron 2020 Apr 22;106(2):237-245.e8

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Soluble epoxide hydrolase inhibitor protects against blood-brain barrier dysfunction in a mouse model of type 2 diabetes via the AMPK/HO-1 pathway.

Wu J, Zhao Y, Fan Z, Chen Q, Chen J, Sun Y, Jiang X, Xiao Q
Biochemical and biophysical research communications 2020 Apr 2;524(2):354-359

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AcMNPV PKIP is required for hyperexpression of very late genes and involved in the hyperphosphorylation of the viral basic protein P6.9.

Lai Q, Xu L, Wang Y, Luo W, Zhu L, Yuan M, Wu W, Yang K
Virus research 2020 Apr 2;279:197889

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Circadian clock gene Clock is involved in the pathogenesis of preeclampsia through hypoxia.

Li Y, Li J, Hou Y, Huang L, Bian Y, Song G, Qiao C
Life sciences 2020 Apr 15;247:117441

---

STIM2 knockdown protects against ischemia/reperfusion injury through reducing mitochondrial calcium overload and preserving mitochondrial function.

Tu CC, Wan BY, Zeng Y
Life sciences 2020 Apr 15;247:116560

---

The SCF(β-TrCP) E3 Ubiquitin Ligase Regulates Immune Receptor Signaling by Targeting the Negative Regulatory Protein TIPE2.

Lou Y, Han M, Song Y, Zhong J, Zhang W, Chen YH, Wang H
Journal of immunology (Baltimore, Md. : 1950) 2020 Apr 15;204(8):2122-2132

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Physicochemical characterization of polysaccharide from the leaf of Dendrobium officinale and effect on LPS induced damage in GES-1 cell.

Yang K, Lu T, Zhan L, Zhou C, Zhang N, Lei S, Wang Y, Yang J, Yan M, Lv G, Chen S
International journal of biological macromolecules 2020 Apr 15;149:320-330

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Trehalose attenuates renal ischemia-reperfusion injury by enhancing autophagy and inhibiting oxidative stress and inflammation.

Liu S, Yang Y, Gao H, Zhou N, Wang P, Zhang Y, Zhang A, Jia Z, Huang S
American journal of physiology. Renal physiology 2020 Apr 1;318(4):F994-F1005

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Localized injection of miRNA-21-enriched extracellular vesicles effectively restores cardiac function after myocardial infarction.

Song Y, Zhang C, Zhang J, Jiao Z, Dong N, Wang G, Wang Z, Wang L
Theranostics 2019;9(8):2346-2360

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HSF2 regulates aerobic glycolysis by suppression of FBP1 in hepatocellular carcinoma.

Yang LN, Ning ZY, Wang L, Yan X, Meng ZQ
American journal of cancer research 2019;9(8):1607-1621

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Oncogenic MSH6-CXCR4-TGFB1 Feedback Loop: A Novel Therapeutic Target of Photothermal Therapy in Glioblastoma Multiforme.

Chen Y, Liu P, Sun P, Jiang J, Zhu Y, Dong T, Cui Y, Tian Y, An T, Zhang J, Li Z, Yang X
Theranostics 2019;9(5):1453-1473

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Targeting mitochondrial dynamics by regulating Mfn2 for therapeutic intervention in diabetic cardiomyopathy.

Hu L, Ding M, Tang D, Gao E, Li C, Wang K, Qi B, Qiu J, Zhao H, Chang P, Fu F, Li Y
Theranostics 2019;9(13):3687-3706

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Triptolide Induces Glioma Cell Autophagy and Apoptosis via Upregulating the ROS/JNK and Downregulating the Akt/mTOR Signaling Pathways.

Liu X, Zhao P, Wang X, Wang L, Zhu Y, Gao W
Frontiers in oncology 2019;9:387

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Identification of RE1-Silencing Transcription Factor as a Promoter of Metastasis in Pancreatic Cancer.

Jin H, Liu P, Kong L, Fei X, Gao Y, Wu T, Sun D, Tan X
Frontiers in oncology 2019;9:291

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Inhibition of oxidative stress by testosterone improves synaptic plasticity in senescence accelerated mice.

Wang L, Pei JH, Jia JX, Wang J, Song W, Fang X, Cai ZP, Huo DS, Wang H, Yang ZJ
Journal of toxicology and environmental health. Part A 2019;82(20):1061-1068

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Evidence for interaction of the NLRP3 inflammasome and Bruton's tyrosine kinase in tumor-associated macrophages: implications for myeloid cell production of interleukin-1beta.

Benner B, Scarberry L, Stiff A, Duggan MC, Good L, Lapurga G, Butchar JP, Tridandapani S, Carson WE
Oncoimmunology 2019;8(11):1659704

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Bergenin Ameliorates MPTP-Induced Parkinson's Disease by Activating PI3K/Akt Signaling Pathway.

Ji Y, Wang D, Zhang B, Lu H
Journal of Alzheimer's disease : JAD 2019;72(3):823-833

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aFGF Promotes Neurite Growth by Regulating GSK3β-CRMP2 Signaling Pathway in Cortical Neurons Damaged by Amyloid-β.

Cao Q, Meng T, Man J, Peng D, Chen H, Xiang Q, Su Z, Zhang Q, Huang Y
Journal of Alzheimer's disease : JAD 2019;72(1):97-109

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Synergetic Inhibition of Human Colorectal Cancer Cells by Combining Polyyne-Enriched Fraction from Oplopanax elatus and Irinotecan.

Wang J, Shao L, Wang CZ, Zhou HH, Yuan CS, Huang WH
Nutrition and cancer 2019;71(3):472-482

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AAV9-Mediated Cdk5 Inhibitory Peptide Reduces Hyperphosphorylated Tau and Inflammation and Ameliorates Behavioral Changes Caused by Overexpression of p25 in the Brain.

Xu M, Huang Y, Song P, Huang Y, Huang W, Zhang HT, Hu Y
Journal of Alzheimer's disease : JAD 2019;70(2):573-585

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MiR-223-3p Alleviates Vascular Endothelial Injury by Targeting IL6ST in Kawasaki Disease.

Wang X, Ding YY, Chen Y, Xu QQ, Qian GH, Qian WG, Cao L, Zhou WP, Hou M, Lv HT
Frontiers in pediatrics 2019;7:288

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Loss of the Golgi Matrix Protein 130 Cause Aberrant IgA1 Glycosylation in IgA Nephropathy.

Wang C, Ye M, Zhao Q, Xia M, Liu D, He L, Chen G, Peng Y, Liu H
American journal of nephrology 2019;49(4):307-316

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Chemo-Preventive Potential of Falcarindiol-Enriched Fraction from Oplopanax elatus on Colorectal Cancer Interfered by Human Gut Microbiota.

Wang J, Shao L, Rao T, Zhang W, Huang WH
The American journal of Chinese medicine 2019;47(6):1381-1404

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Cinobufagin Promotes Cell Cycle Arrest and Apoptosis to Block Human Esophageal Squamous Cell Carcinoma Cells Growth via the p73 Signalling Pathway.

Deng X, Sheng J, Liu H, Wang N, Dai C, Wang Z, Zhang J, Zhao J, Dai E
Biological & pharmaceutical bulletin 2019;42(9):1500-1509

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Loss of Mitochondrial DNA by Gemcitabine Triggers Mitophagy and Cell Death.

Inamura A, Muraoka-Hirayama S, Sakurai K
Biological & pharmaceutical bulletin 2019;42(12):1977-1987

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RNA-seq analysis of PHD and VHL inhibitors reveals differences and similarities to the hypoxia response.

Frost J, Ciulli A, Rocha S
Wellcome open research 2019;4:17

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The Role of Nrf2 Signaling Pathway in Eucommia ulmoides Flavones Regulating Oxidative Stress in the Intestine of Piglets.

Xiao D, Yuan D, Tan B, Wang J, Liu Y, Tan B
Oxidative medicine and cellular longevity 2019;2019:9719618

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Dexmedetomidine Attenuates Orthotopic Liver Transplantation-Induced Acute Gut Injury via α (2)-Adrenergic Receptor-Dependent Suppression of Oxidative Stress.

Lv P, Chen T, Liu P, Zheng L, Tian J, Tan F, Chen J, Deng Y, Li J, Cai J, Chi X
Oxidative medicine and cellular longevity 2019;2019:9426368

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Paneth Cell Ablation Aggravates Pancreatic and Intestinal Injuries in a Rat Model of Acute Necrotizing Pancreatitis after Normal and High-Fat Diet.

Guo Y, Huang C, Liu L, Fu X, Lu Y, Zheng J, Mei Q, Huang Z, Fan J, Lu L, Zeng Y
Mediators of inflammation 2019;2019:8474523

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Palmitic Acid Induces MicroRNA-221 Expression to Decrease Glucose Uptake in HepG2 Cells via the PI3K/AKT/GLUT4 Pathway.

Huang F, Chen J, Wang J, Zhu P, Lin W
BioMed research international 2019;2019:8171989

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Tetrandrine-Induced Autophagy in MDA-MB-231 Triple-Negative Breast Cancer Cell through the Inhibition of PI3K/AKT/mTOR Signaling.

Guo Y, Pei X
Evidence-based complementary and alternative medicine : eCAM 2019;2019:7517431

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N-n-Butyl Haloperidol Iodide Ameliorates Oxidative Stress in Mitochondria Induced by Hypoxia/Reoxygenation through the Mitochondrial c-Jun N-Terminal Kinase/Sab/Src/Reactive Oxygen Species Pathway in H9c2 Cells.

Chu Q, Zhang Y, Zhong S, Gao F, Chen Y, Wang B, Zhang Z, Cai W, Li W, Zheng F, Shi G
Oxidative medicine and cellular longevity 2019;2019:7417561

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Oral Administration of Lactobacillus delbrueckii during the Suckling Phase Improves Antioxidant Activities and Immune Responses after the Weaning Event in a Piglet Model.

Li Y, Hou S, Peng W, Lin Q, Chen F, Yang L, Li F, Huang X
Oxidative medicine and cellular longevity 2019;2019:6919803

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Minocycline Protects against Rotenone-Induced Neurotoxicity Correlating with Upregulation of Nurr1 in a Parkinson's Disease Rat Model.

Sun C, Wang Y, Mo M, Song C, Wang X, Chen S, Liu Y
BioMed research international 2019;2019:6843265

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Phosphocreatine Improves Cardiac Dysfunction by Normalizing Mitochondrial Respiratory Function through JAK2/STAT3 Signaling Pathway In Vivo and In Vitro.

Qaed E, Wang J, Almoiliqy M, Song Y, Liu W, Chu P, Alademi S, Alademi M, Li H, Alshwmi M, Al-Azab M, Ahsan A, Mahdi S, Han G, Niu M, Ali A, Shopit A, Wang H, Li X, Qaid A, Ma X, Li T, Peng J, Ma J, Zhang J, Tang Z
Oxidative medicine and cellular longevity 2019;2019:6521218

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CD133 Is Associated with Increased Melanoma Cell Survival after Multikinase Inhibition.

Simbulan-Rosenthal CM, Gaur A, Zhou H, AbdusSamad M, Qin Q, Dougherty R, Aljehane L, Kuo LW, Vakili S, Karna K, Clark H, McCarron E, Rosenthal DS
Journal of oncology 2019;2019:6486173

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CTGF Attenuates Tendon-Derived Stem/Progenitor Cell Aging.

Rui YF, Chen MH, Li YJ, Xiao LF, Geng P, Wang P, Xu ZY, Zhang XP, Dai GC
Stem cells international 2019;2019:6257537

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Reactive Oxygen Species Are Involved in the Development of Gastric Cancer and Gastric Cancer-Related Depression through ABL1-Mediated Inflammation Signaling Pathway.

Huang T, Zhou F, Yuan X, Yang T, Liang X, Wang Y, Tu H, Chang J, Nan K, Wei Y
Oxidative medicine and cellular longevity 2019;2019:5813985

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Purple Sweet Potato Color Attenuates Kidney Damage by Blocking VEGFR2/ROS/NLRP3 Signaling in High-Fat Diet-Treated Mice.

Zheng GH, Shan Q, Mu JJ, Wang YJ, Zhang ZF, Fan SH, Hu B, Li MQ, Xie J, Chen P, Wu DM, Lu J, Zheng YL
Oxidative medicine and cellular longevity 2019;2019:5189819

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Nicorandil Attenuates LPS-Induced Acute Lung Injury by Pulmonary Endothelial Cell Protection via NF-κB and MAPK Pathways.

He M, Shi W, Yu M, Li X, Xu J, Zhu J, Jin L, Xie W, Kong H
Oxidative medicine and cellular longevity 2019;2019:4957646

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Shuangyu Tiaozhi Granule Attenuates Hypercholesterolemia through the Reduction of Cholesterol Synthesis in Rat Fed a High Cholesterol Diet.

Shi J, Li R, Liu Y, Lu H, Yu L, Zhang F
BioMed research international 2019;2019:4805926

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Prevention of Huntington's Disease-Like Behavioral Deficits in R6/1 Mouse by Tolfenamic Acid Is Associated with Decreases in Mutant Huntingtin and Oxidative Stress.

Liu P, Li Y, Yang W, Liu D, Ji X, Chi T, Guo Z, Li L, Zou L
Oxidative medicine and cellular longevity 2019;2019:4032428

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Bu Shen Zhu Yun Decoction Improves Endometrial Receptivity via VEGFR-2-Mediated Angiogenesis.

Li L, Jiang H, Wei X, Geng D, He M, Du H
Evidence-based complementary and alternative medicine : eCAM 2019;2019:3949824

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Yiqihuoxue Formula Activates Autophagy and Offers Renoprotection in a Rat Model of Adenine-Induced Kidney Disease.

Xia CH, Han XT, Zhang X, Zhu ZB, Guo J, Cui HL, Jiang HX, Huang WJ, Chen GZ, Liu YN, Liu WJ
Evidence-based complementary and alternative medicine : eCAM 2019;2019:3423981

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Curcumin and Curcumol Inhibit NF-κB and TGF-β (1)/Smads Signaling Pathways in CSE-Treated RAW246.7 Cells.

Li N, Liu TH, Yu JZ, Li CX, Liu Y, Wu YY, Yang ZS, Yuan JL
Evidence-based complementary and alternative medicine : eCAM 2019;2019:3035125

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Astragalus Membranaceus Treatment Protects Raw264.7 Cells from Influenza Virus by Regulating G1 Phase and the TLR3-Mediated Signaling Pathway.

Liang Y, Zhang Q, Zhang L, Wang R, Xu X, Hu X
Evidence-based complementary and alternative medicine : eCAM 2019;2019:2971604

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Salvianolic Acid A Protects the Kidney against Oxidative Stress by Activating the Akt/GSK-3β/Nrf2 Signaling Pathway and Inhibiting the NF-κB Signaling Pathway in 5/6 Nephrectomized Rats.

Zhang HF, Wang JH, Wang YL, Gao C, Gu YT, Huang J, Wang JH, Zhang Z
Oxidative medicine and cellular longevity 2019;2019:2853534

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Stem Cells from Human Exfoliated Deciduous Teeth Ameliorate Diabetic Nephropathy In Vivo and In Vitro by Inhibiting Advanced Glycation End Product-Activated Epithelial-Mesenchymal Transition.

Rao N, Wang X, Xie J, Li J, Zhai Y, Li X, Fang T, Wang Y, Zhao Y, Ge L
Stem cells international 2019;2019:2751475

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Leukemia Inhibitory Factor Receptor Is Involved in Apoptosis in Rat Astrocytes Exposed to Oxygen-Glucose Deprivation.

Huo L, Fan Y, Wang H
BioMed research international 2019;2019:1613820

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Astragaloside IV Suppresses High Glucose-Induced NLRP3 Inflammasome Activation by Inhibiting TLR4/NF-κB and CaSR.

Leng B, Zhang Y, Liu X, Zhang Z, Liu Y, Wang H, Lu M
Mediators of inflammation 2019;2019:1082497

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miR-100-3p inhibits cell proliferation and induces apoptosis in human gastric cancer through targeting to BMPR2.

Peng CW, Yue LX, Zhou YQ, Tang S, Kan C, Xia LM, Yang F, Wang SY
Cancer cell international 2019;19:354

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SSRP1 influences colorectal cancer cell growth and apoptosis via the AKT pathway.

Wang Q, Jia S, Jiao Y, Xu L, Wang D, Chen X, Hu X, Liang H, Wen N, Zhang S, Guo B, Zhang L
International journal of medical sciences 2019;16(12):1573-1582

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Fucoidan prevent murine autoimmune diabetes via suppression TLR4-signaling pathways, regulation DC/Treg induced immune tolerance and improving gut microecology.

Xue M, Liang H, Ji X, Liu Y, Ge Y, Hou L, Sun T
Nutrition & metabolism 2019;16:87

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CXXC5 Mediates P. gingivalis-suppressed Cementoblast Functions Partially via MAPK Signaling Network.

Ma L, Wang X, Liu H, Jiang C, Liao H, Xu S, Guo Y, Cao Z
International journal of biological sciences 2019;15(8):1685-1695

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Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts.

Dias HB, de Oliveira JR, Donadio MVF, Kimura S
PloS one 2019;14(9):e0222202

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SPSB2 inhibits hepatitis C virus replication by targeting NS5A for ubiquitination and degradation.

Wang M, Wang Y, Liu Y, Wang H, Xin X, Li J, Hao Y, Han L, Yu F, Zheng C, Shen C
PloS one 2019;14(7):e0219989

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Resveratrol induced premature senescence and inhibited epithelial-mesenchymal transition of cancer cells via induction of tumor suppressor Rad9.

Chen KY, Chen CC, Chang YC, Chang MC
PloS one 2019;14(7):e0219317

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The Pseudogene PTTG3P Promotes Cell Migration and Invasion in Esophageal Squamous Cell Carcinoma.

Zhang Z, Shi Z
Open medicine (Warsaw, Poland) 2019;14:516-522

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Synergism of cisplatin-oleanolic acid co-loaded calcium carbonate nanoparticles on hepatocellular carcinoma cells for enhanced apoptosis and reduced hepatotoxicity.

Khan MW, Zhao P, Khan A, Raza F, Raza SM, Sarfraz M, Chen Y, Li M, Yang T, Ma X, Xiang G
International journal of nanomedicine 2019;14:3753-3771

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Treatment With Liraglutide Exerts Neuroprotection After Hypoxic-Ischemic Brain Injury in Neonatal Rats via the PI3K/AKT/GSK3β Pathway.

Zeng SS, Bai JJ, Jiang H, Zhu JJ, Fu CC, He MZ, Zhu JH, Chen SQ, Li PJ, Fu XQ, Lin ZL
Frontiers in cellular neuroscience 2019;13:585

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Overexpression of CX3CR1 in Adipose-Derived Stem Cells Promotes Cell Migration and Functional Recovery After Experimental Intracerebral Hemorrhage.

Li G, Yu H, Liu N, Zhang P, Tang Y, Hu Y, Zhang Y, Pan C, Deng H, Wang J, Li Q, Tang Z
Frontiers in neuroscience 2019;13:462

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Arsenic sulfide induces miR-4665-3p to inhibit gastric cancer cell invasion and migration.

Zhang X, Tan Z, Kang T, Zhu C, Chen S
Drug design, development and therapy 2019;13:3037-3049

---

Hydrogen Sulfide Attenuates β2-Microglobulin-Induced Cognitive Dysfunction: Involving Recovery of Hippocampal Autophagic Flux.

Chen SM, Yi YL, Zeng D, Tang YY, Kang X, Zhang P, Zou W, Tang XQ
Frontiers in behavioral neuroscience 2019;13:244

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Necrostatin-1 Ameliorates Peripheral Nerve Injury-Induced Neuropathic Pain by Inhibiting the RIP1/RIP3 Pathway.

Liang YX, Wang NN, Zhang ZY, Juan ZD, Zhang C
Frontiers in cellular neuroscience 2019;13:211

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The Neuroprotection of KIBRA in Promoting Neuron Survival and Against Amyloid β-Induced Apoptosis.

Song L, Tang S, Dong L, Han X, Cong L, Dong J, Han X, Zhang Q, Wang Y, Du Y
Frontiers in cellular neuroscience 2019;13:137

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SUMOylation and deacetylation affect NF-κB p65 activity induced by high glucose in human lens epithelial cells.

Han X, Dong XX, Shi MY, Feng L, Wang XL, Zhang JS, Yan QC
International journal of ophthalmology 2019;12(9):1371-1379

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PAR-2 promotes invasion and migration of esophageal cancer cells by activating MEK/ERK and PI3K/Akt signaling pathway.

Sheng J, Deng X, Zhang Q, Liu H, Wang N, Liu Z, Dai E, Deng Q
International journal of clinical and experimental pathology 2019;12(3):787-797

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Gatifloxacin inducing apoptosis of stromal fibroblasts through cross-talk between caspase-dependent extrinsic and intrinsic pathways.

Xu B, Sui YL, Fan TJ
International journal of ophthalmology 2019;12(10):1524-1530

---

Expression Of BMP7 In Ovarian Cancer And Biological Effect Of BMP7 Knockdown On Ovarian Cancer Cells.

Guan H, Li J, Sun R, Liu W, Feng M, Ma H, Li C
OncoTargets and therapy 2019;12:7897-7909

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MicroRNA-765 sensitizes osteosarcoma cells to cisplatin via downregulating APE1 expression.

Liang W, Li C, Li M, Wang D, Zhong Z
OncoTargets and therapy 2019;12:7203-7214

---

LAPTM4B knockdown increases the radiosensitivity of EGFR-overexpressing radioresistant nasopharyngeal cancer cells by inhibiting autophagy.

Chu C, Niu X, Ou X, Hu C
OncoTargets and therapy 2019;12:5661-5677

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β-elemene inhibits radiation and hypoxia-induced macrophages infiltration via Prx-1/NF-κB/HIF-1α signaling pathway.

Yu X, Li Z, Zhang Y, Xu M, Che Y, Tian X, Wang R, Zou K, Zou L
OncoTargets and therapy 2019;12:4203-4211

---

Exosomal Tenascin-c induces proliferation and invasion of pancreatic cancer cells by WNT signaling.

Qian S, Tan X, Liu X, Liu P, Wu Y
OncoTargets and therapy 2019;12:3197-3205

---

Multiple Functions of KBP in Neural Development Underlie Brain Anomalies in Goldberg-Shprintzen Syndrome.

Chang HY, Cheng HY, Tsao AN, Liu C, Tsai JW
Frontiers in molecular neuroscience 2019;12:265

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Dichloroacetic acid upregulates apoptosis of ovarian cancer cells by regulating mitochondrial function.

Zhou L, Liu L, Chai W, Zhao T, Jin X, Guo X, Han L, Yuan C
OncoTargets and therapy 2019;12:1729-1739

---

miR-492 Promotes Cancer Progression by Targeting GJB4 and Is a Novel Biomarker for Bladder Cancer.

Wang K, Lü H, Qu H, Xie Q, Sun T, Gan O, Hu B
OncoTargets and therapy 2019;12:11453-11464

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miR-509-5p Downregulation Is Associated With Male Infertility And Acts As A Suppressor In Testicular Germ Cell Tumor Cells Through Targeting MDM2.

Sun J, Niu L, Gao S, Yi X, Chen J
OncoTargets and therapy 2019;12:10515-10522

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Escin protects against acetaminophen-induced liver injury in mice via attenuating inflammatory response and inhibiting ERK signaling pathway.

Lee HC, Yu HP, Liao CC, Chou AH, Liu FC
American journal of translational research 2019;11(8):5170-5182

---

MiR-302a-5p suppresses cell proliferation and invasion in non-small cell lung carcinoma by targeting ITGA6.

Chen W, Zhuang X, Qi R, Qiao T
American journal of translational research 2019;11(7):4348-4357

---

VASN promotes YAP/TAZ and EMT pathway in thyroid carcinogenesis in vitro.

Bhandari A, Guan Y, Xia E, Huang Q, Chen Y
American journal of translational research 2019;11(6):3589-3599

---

Overexpression of CBX2 in breast cancer promotes tumor progression through the PI3K/AKT signaling pathway.

Zheng S, Lv P, Su J, Miao K, Xu H, Li M
American journal of translational research 2019;11(3):1668-1682

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BPTF cooperates with p50 NF-κB to promote COX-2 expression and tumor cell growth in lung cancer.

Dai M, Hu S, Liu CF, Jiang L, Yu W, Li ZL, Guo W, Tang R, Dong CY, Wu TH, Deng WG
American journal of translational research 2019;11(12):7398-7409

---

Clinical roles of miR-136-5p and its target metadherin in thyroid carcinoma.

Gao RZ, Que Q, Lin P, Pang YY, Wu HY, Li XJ, Chen G, He Y, Yang H
American journal of translational research 2019;11(11):6754-6774

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Downregulation of angiopoietin-like protein 2 inhibits cementoblast differentiation partially by activating the ERK1/2 signaling pathway.

Jiang C, Liu H, Sun H, Wang X, Liao H, Ma L, Cao Z
American journal of translational research 2019;11(1):314-326

---

ADAR1 may be involved in the proliferation of acute myeloid leukemia cells via regulation of the Wnt pathway.

Xiao H, Cheng Q, Wu X, Tang Y, Liu J, Li X
Cancer management and research 2019;11:8547-8555

---

Overexpressed PKMYT1 promotes tumor progression and associates with poor survival in esophageal squamous cell carcinoma.

Zhang Q, Zhao X, Zhang C, Wang W, Li F, Liu D, Wu K, Zhu D, Liu S, Shen C, Yuan X, Zhang K, Yang Y, Zhang Y, Zhao S
Cancer management and research 2019;11:7813-7824

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HIF1α/miR-520a-3p/AKT1/mTOR Feedback Promotes The Proliferation And Glycolysis Of Gastric Cancer Cells.

Pan C, Liu Q, Wu X
Cancer management and research 2019;11:10145-10156

---

STIP1 Regulates Proliferation and Migration of Lung Adenocarcinoma Through JAK2/STAT3 Signaling Pathway.

Guo X, Yan Z, Zhang G, Wang X, Pan Y, Huang M
Cancer management and research 2019;11:10061-10072

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Inhibition of RNA-Binding Protein Musashi-1 Suppresses Malignant Properties and Reverses Paclitaxel Resistance in Ovarian Carcinoma.

Chen H, Liu J, Wang H, Cheng Q, Zhou C, Chen X, Ye F
Journal of Cancer 2019;10(6):1580-1592

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CLEC4M is associated with poor prognosis and promotes cisplatin resistance in NSCLC patients.

Tan LM, Li X, Qiu CF, Zhu T, Hu CP, Yin JY, Zhang W, Zhou HH, Liu ZQ
Journal of Cancer 2019;10(25):6374-6383

---

Methylation of SLFN11 promotes gastric cancer growth and increases gastric cancer cell resistance to cisplatin.

Peng Y, Wang L, Wu L, Zhang L, Nie G, Guo M
Journal of Cancer 2019;10(24):6124-6134

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EP300 as an oncogene correlates with poor prognosis in esophageal squamous carcinoma.

Bi Y, Kong P, Zhang L, Cui H, Xu X, Chang F, Yan T, Li J, Cheng C, Song B, Niu X, Liu X, Liu X, Xu E, Hu X, Qian Y, Wang F, Li H, Ma Y, Yang J, Liu Y, Zhai Y, Wang Y, Zhang Y, Liu H, Liu J, Wang J, Cui Y, Cheng X
Journal of Cancer 2019;10(22):5413-5426

---

8-bromo-7-methoxychrysin targets NF-κB and FoxM1 to inhibit lung cancer stem cells induced by pro-inflammatory factors.

Yuan Q, Wen M, Xu C, Chen A, Qiu YB, Cao JG, Zhang JS, Song ZW
Journal of Cancer 2019;10(21):5244-5255

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An NF90/long noncoding RNA-LET/miR-548k feedback amplification loop controls esophageal squamous cell carcinoma progression.

Lin J, Chen Z, Wu S, Huang W, Chen F, Huang Z
Journal of Cancer 2019;10(21):5139-5152

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Verteporfin suppresses the proliferation, epithelial-mesenchymal transition and stemness of head and neck squamous carcinoma cells via inhibiting YAP1.

Liu K, Du S, Gao P, Zheng J
Journal of Cancer 2019;10(18):4196-4207

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ITRAQ-Based Proteomics Analysis Reveals the Effect of Neoliensinine on KCl-Induced Vascular Smooth Muscle Contraction by Inhibiting Regulatory Light Chain Phosphorylation.

Yang GM, Yan K, Wang P, Zhang JL, Pan ZH, Pan Y
Frontiers in pharmacology 2019;10:979

---

Discovery of N-(2-Aminophenyl)-4-(bis(2-chloroethyl)amino)Benzamide as a Potent Histone Deacetylase Inhibitor.

Zhang L, Li X, Chen Y, Wan M, Jiang Q, Zhang L, Chou CJ, Song W, Zhang L
Frontiers in pharmacology 2019;10:957

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A Novel Regulatory Circuit "C/EBPα/miR-20a-5p/TOB2" Regulates Adipogenesis and Lipogenesis.

Zhou J, Yang J, Wang X, Li M, Li F, Zhu E, Li X, Li X, Wang B
Frontiers in endocrinology 2019;10:894

---

Effects of Exercise Training on the Autophagy-Related Muscular Proteins Expression in Ovariectomized Rats.

Zhong W, Shi X, Yuan H, Bu H, Wu L, Wang R
Frontiers in physiology 2019;10:735

---

Irbesartan Ameliorates Lipid Deposition by Enhancing Autophagy via PKC/AMPK/ULK1 Axis in Free Fatty Acid Induced Hepatocytes.

He J, Ding J, Lai Q, Wang X, Li A, Liu S
Frontiers in physiology 2019;10:681

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Fish Autophagy Protein 5 Exerts Negative Regulation on Antiviral Immune Response Against Iridovirus and Nodavirus.

Li C, Liu J, Zhang X, Wei S, Huang X, Huang Y, Wei J, Qin Q
Frontiers in immunology 2019;10:517

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A Novel Postbiotic From Lactobacillus rhamnosus GG With a Beneficial Effect on Intestinal Barrier Function.

Gao J, Li Y, Wan Y, Hu T, Liu L, Yang S, Gong Z, Zeng Q, Wei Y, Yang W, Zeng Z, He X, Huang SH, Cao H
Frontiers in microbiology 2019;10:477

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An improved Tet-on system in microRNA overexpression and CRISPR/Cas9-mediated gene editing.

Kang K, Huang L, Li Q, Liao X, Dang Q, Yang Y, Luo J, Zeng Y, Li L, Gou D
Journal of animal science and biotechnology 2019;10:43

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Identification of a Novel Bcl-2 Inhibitor by Ligand-Based Screening and Investigation of Its Anti-cancer Effect on Human Breast Cancer Cells.

Wen M, Deng ZK, Jiang SL, Guan YD, Wu HZ, Wang XL, Xiao SS, Zhang Y, Yang JM, Cao DS, Cheng Y
Frontiers in pharmacology 2019;10:391

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Prepartum body conditions affect insulin signaling pathways in postpartum adipose tissues in transition dairy cows.

Zhang F, Li D, Wu Q, Sun J, Guan W, Hou Y, Zhu Y, Wang J
Journal of animal science and biotechnology 2019;10:38

---

Da-Bu-Yin-Wan and Qian-Zheng-San Ameliorate Mitochondrial Dynamics in the Parkinson's Disease Cell Model Induced by MPP().

Gai C, Feng WD, Qiang TY, Ma HJ, Chai Y, Zhang SJ, Guo ZY, Hu JH, Sun HM
Frontiers in pharmacology 2019;10:372

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The Involvement of Renin-Angiotensin System in Lipopolysaccharide-Induced Behavioral Changes, Neuroinflammation, and Disturbed Insulin Signaling.

Gong X, Hu H, Qiao Y, Xu P, Yang M, Dang R, Han W, Guo Y, Chen D, Jiang P
Frontiers in pharmacology 2019;10:318

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Epstein-Barr Virus Nuclear Antigen 1 Recruits Cyclophilin A to Facilitate the Replication of Viral DNA Genome.

Xin S, Du S, Liu L, Xie Y, Zuo L, Yang J, Hu J, Yue W, Zhang J, Cao P, Zhu F, Lu J
Frontiers in microbiology 2019;10:2879

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Dengue Virus Infection Activates Interleukin-1β to Induce Tissue Injury and Vascular Leakage.

Pan P, Zhang Q, Liu W, Wang W, Yu Z, Lao Z, Zhang W, Shen M, Wan P, Xiao F, Shereen MA, Zhang W, Tan Q, Liu Y, Liu X, Wu K, Liu Y, Li G, Wu J
Frontiers in microbiology 2019;10:2637

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Hypertensive Rats Treated Chronically With N(ω)-Nitro-L-Arginine Methyl Ester (L-NAME) Induced Disorder of Hepatic Fatty Acid Metabolism and Intestinal Pathophysiology.

Li B, He X, Lei SS, Zhou FC, Zhang NY, Chen YH, Wang YZ, Su J, Yu JJ, Li LZ, Zheng X, Luo R, Kołodyńska D, Xiong S, Lv GY, Chen SH
Frontiers in pharmacology 2019;10:1677

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Cathelicidin-WA Facilitated Intestinal Fatty Acid Absorption Through Enhancing PPAR-γ Dependent Barrier Function.

Zong X, Cao X, Wang H, Xiao X, Wang Y, Lu Z
Frontiers in immunology 2019;10:1674

---

The Capsid Protein VP1 of Coxsackievirus B Induces Cell Cycle Arrest by Up-Regulating Heat Shock Protein 70.

Wang Y, Zhao S, Chen Y, Wang T, Dong C, Wo X, Zhang J, Dong Y, Xu W, Feng X, Qu C, Wang Y, Zhong Z, Zhao W
Frontiers in microbiology 2019;10:1633

---

LncRNA LUCRC Regulates Colorectal Cancer Cell Growth and Tumorigenesis by Targeting Endoplasmic Reticulum Stress Response.

Tang GH, Chen X, Ding JC, Du J, Lin XT, Xia L, Lian JB, Ye F, He XS, Liu W
Frontiers in genetics 2019;10:1409

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Ghrelin Attenuates Neuroinflammation and Demyelination in Experimental Autoimmune Encephalomyelitis Involving NLRP3 Inflammasome Signaling Pathway and Pyroptosis.

Liu F, Li Z, He X, Yu H, Feng J
Frontiers in pharmacology 2019;10:1320

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An Improved Enzyme-Linked Focus Formation Assay Revealed Baloxavir Acid as a Potential Antiviral Therapeutic Against Hantavirus Infection.

Ye C, Wang D, Liu H, Ma H, Dong Y, Yao M, Wang Y, Zhang H, Zhang L, Cheng L, Xu Z, Lei Y, Zhang F, Ye W
Frontiers in pharmacology 2019;10:1203

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LPS Induces Preeclampsia-Like Phenotype in Rats and HTR8/SVneo Cells Dysfunction Through TLR4/p38 MAPK Pathway.

Fan M, Li X, Gao X, Dong L, Xin G, Chen L, Qiu J, Xu Y
Frontiers in physiology 2019;10:1030

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Sorghum Phenolics Inhibits Inflammasomes in Lipopolysaccharide (LPS)-Primed and Adenosine Triphosphate (ATP)-Activated Macrophages.

Dia VP, Bradwell J, Pangloli P
Plant foods for human nutrition (Dordrecht, Netherlands) 2019 Sep;74(3):307-315

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Functional evidence for a de novo mutation in WDR45 leading to BPAN in a Chinese girl.

Xiong Q, Li W, Li P, Zhao Z, Wu C, Xiao H
Molecular genetics & genomic medicine 2019 Sep;7(9):e858

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Aerobic Exercise Improves Synaptic-Related Proteins of Diabetic Rats by Inhibiting FOXO1/NF-κB/NLRP3 Inflammatory Signaling Pathway and Ameliorating PI3K/Akt Insulin Signaling Pathway.

Wang Q, Hu J, Liu Y, Li J, Liu B, Li M, Lou S
Journal of molecular neuroscience : MN 2019 Sep;69(1):28-38

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Comparison of the Effects of Green and Black Tea Extracts on Na(+) /K(+) -ATPase Activity in Intestine of Type 1 and Type 2 Diabetic Mice.

Qu F, Liu S, He C, Zhou J, Zhang S, Ai Z, Chen Y, Yu Z, Ni D
Molecular nutrition & food research 2019 Sep;63(17):e1801039

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Mechanosensitive ion channel Piezo1 promotes prostate cancer development through the activation of the Akt/mTOR pathway and acceleration of cell cycle.

Han Y, Liu C, Zhang D, Men H, Huo L, Geng Q, Wang S, Gao Y, Zhang W, Zhang Y, Jia Z
International journal of oncology 2019 Sep;55(3):629-644

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MicroRNA-191 promotes hepatocellular carcinoma cell proliferation by has_circ_0000204/miR-191/KLF6 axis.

Tian F, Yu C, Wu M, Wu X, Wan L, Zhu X
Cell proliferation 2019 Sep;52(5):e12635

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Cardiac troponin I autoantibody induces myocardial dysfunction by PTEN signaling activation.

Wu Y, Qin YH, Liu Y, Zhu L, Zhao XX, Liu YY, Luo SW, Tang GS, Shen Q
EBioMedicine 2019 Sep;47:329-340

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DEPDC1 drives hepatocellular carcinoma cell proliferation, invasion and angiogenesis by regulating the CCL20/CCR6 signaling pathway.

Guo W, Li H, Liu H, Ma X, Yang S, Wang Z
Oncology reports 2019 Sep;42(3):1075-1089

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Eukaryotic elongation factor-2 kinase regulates the cross-talk between autophagy and pyroptosis in doxorubicin-treated human melanoma cells in vitro.

Yu P, Wang HY, Tian M, Li AX, Chen XS, Wang XL, Zhang Y, Cheng Y
Acta pharmacologica Sinica 2019 Sep;40(9):1237-1244

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The Functional Polymorphism R129W in the BVES Gene Is Associated with Sporadic Tetralogy of Fallot in the Han Chinese Population.

Shi Y, Li Y, Wang Y, Zhuang J, Wang H, Hu M, Mo X, Yue S, Chen Y, Fan X, Chen J, Cai W, Zhu X, Wan Y, Zhong Y, Ye X, Li F, Zhou Z, Dai G, Luo R, Ocorr K, Jiang Z, Li X, Zhu P, Wu X, Yuan W
Genetic testing and molecular biomarkers 2019 Sep;23(9):601-609

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Ursolic acid suppresses the invasive potential of colorectal cancer cells by regulating the TGF-β1/ZEB1/miR-200c signaling pathway.

Zhang L, Cai QY, Liu J, Peng J, Chen YQ, Sferra TJ, Lin JM
Oncology letters 2019 Sep;18(3):3274-3282

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2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone induced apoptosis and G1 cell cycle arrest through PI3K/AKT pathway in BEL-7402/5-FU cells.

Ji X, Wei X, Qian J, Mo X, Kai G, An F, Lu Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Sep;131:110533

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HOXA11-AS regulates JAK-STAT pathway by miR-15a-3p/STAT3 axis to promote the growth and metastasis in liver cancer.

Wang S, Zhang S, He Y, Huang X, Hui Y, Tang Y
Journal of cellular biochemistry 2019 Sep;120(9):15941-15951

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SARI attenuates colon inflammation by promoting STAT1 degradation in intestinal epithelial cells.

Dai L, Liu Y, Cheng L, Wang H, Lin Y, Shi G, Dong Z, Li J, Fan P, Wang Q, Su X, Zhang S, Yang Y, Hu X, Huang W, Zhou Z, Yu D, Probert C, Wei Y, Deng H
Mucosal immunology 2019 Sep;12(5):1130-1140

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Induction of Nrf2 pathway by Dendrobium nobile Lindl. alkaloids protects against carbon tetrachloride induced acute liver injury.

Li S, Zhou J, Xu S, Li J, Liu J, Lu Y, Shi J, Zhou S, Wu Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109073

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A hidden human proteome encoded by 'non-coding' genes.

Lu S, Zhang J, Lian X, Sun L, Meng K, Chen Y, Sun Z, Yin X, Li Y, Zhao J, Wang T, Zhang G, He QY
Nucleic acids research 2019 Sep 5;47(15):8111-8125

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LINC01123, a c-Myc-activated long non-coding RNA, promotes proliferation and aerobic glycolysis of non-small cell lung cancer through miR-199a-5p/c-Myc axis.

Hua Q, Jin M, Mi B, Xu F, Li T, Zhao L, Liu J, Huang G
Journal of hematology & oncology 2019 Sep 5;12(1):91

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CDK5-dependent phosphorylation and nuclear translocation of TRIM59 promotes macroH2A1 ubiquitination and tumorigenicity.

Sang Y, Li Y, Zhang Y, Alvarez AA, Yu B, Zhang W, Hu B, Cheng SY, Feng H
Nature communications 2019 Sep 5;10(1):4013

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Applying vibration in early postmenopausal osteoporosis promotes osteogenic differentiation of bone marrow-derived mesenchymal stem cells and suppresses postmenopausal osteoporosis progression.

Li H, Wu W, He X, Cao C, Yu X, Zeng Y, Li L
Bioscience reports 2019 Sep 30;39(9)

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Fine particulate matters induce apoptosis via the ATM/P53/CDK2 and mitochondria apoptosis pathway triggered by oxidative stress in rat and GC-2spd cell.

Liu J, Zhang J, Ren L, Wei J, Zhu Y, Duan J, Jing L, Sun Z, Zhou X
Ecotoxicology and environmental safety 2019 Sep 30;180:280-287

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NRF2-dependent gene expression promotes ciliogenesis and Hedgehog signaling.

Martin-Hurtado A, Martin-Morales R, Robledinos-Antón N, Blanco R, Palacios-Blanco I, Lastres-Becker I, Cuadrado A, Garcia-Gonzalo FR
Scientific reports 2019 Sep 25;9(1):13896

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MiR-143-3p directly targets GLUT9 to reduce uric acid reabsorption and inflammatory response of renal tubular epithelial cells.

Zhou Z, Dong Y, Zhou H, Liu J, Zhao W
Biochemical and biophysical research communications 2019 Sep 24;517(3):413-420

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Kinsenoside ameliorates intervertebral disc degeneration through the activation of AKT-ERK1/2-Nrf2 signaling pathway.

Wang Y, Zuo R, Wang Z, Luo L, Wu J, Zhang C, Liu M, Shi C, Zhou Y
Aging 2019 Sep 23;11(18):7961-7977

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Accelerated Metabolite Levels of Aerobic Glycolysis and the Pentose Phosphate Pathway Are Required for Efficient Replication of Infectious Spleen and Kidney Necrosis Virus in Chinese Perch Brain Cells.

Guo X, Wu S, Li N, Lin Q, Liu L, Liang H, Niu Y, Huang Z, Fu X
Biomolecules 2019 Sep 2;9(9)

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Long non-coding RNA, HOTAIRM1, promotes glioma malignancy by forming a ceRNA network.

Liang Q, Li X, Guan G, Xu X, Chen C, Cheng P, Cheng W, Wu A
Aging 2019 Sep 2;11(17):6805-6838

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Maltol (3-Hydroxy-2-methyl-4-pyrone) Slows d-Galactose-Induced Brain Aging Process by Damping the Nrf2/HO-1-Mediated Oxidative Stress in Mice.

Sha JY, Zhou YD, Yang JY, Leng J, Li JH, Hu JN, Liu W, Jiang S, Wang YP, Chen C, Li W
Journal of agricultural and food chemistry 2019 Sep 18;67(37):10342-10351

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Exosomes derived from cardiac progenitor cells attenuate CVB3-induced apoptosis via abrogating the proliferation of CVB3 and modulating the mTOR signaling pathways.

Li X, Yang Z, Nie W, Jiang J, Li S, Li Z, Tian L, Ma X
Cell death & disease 2019 Sep 18;10(10):691

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Bisdemethoxycurcumin Protection of Cardiomyocyte Mainly Depends on Nrf2/HO-1 Activation Mediated by the PI3K/AKT Pathway.

Li X, Huo C, Xiao Y, Xu R, Liu Y, Jia X, Wang X
Chemical research in toxicology 2019 Sep 16;32(9):1871-1879

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Regulatory effect of a Chinese herbal medicine formula on non-alcoholic fatty liver disease.

Yang JM, Sun Y, Wang M, Zhang XL, Zhang SJ, Gao YS, Chen L, Wu MY, Zhou L, Zhou YM, Wang Y, Zheng FJ, Li YH
World journal of gastroenterology 2019 Sep 14;25(34):5105-5119

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Artocarmitin B enhances intracellular antioxidant capacity via activation of Nrf2 signaling pathway in human lung epithelial cells.

Wu XY, Chen XM, Zhou MX, Hu HX, Zhang JZ, Wang XN, Ren DM, Lou HX, Shen T
Chemico-biological interactions 2019 Sep 1;310:108741

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Tetrandrine and cepharanthine induce apoptosis through caspase cascade regulation, cell cycle arrest, MAPK activation and PI3K/Akt/mTOR signal modification in glucocorticoid resistant human leukemia Jurkat T cells.

Xu W, Wang X, Tu Y, Masaki H, Tanaka S, Onda K, Sugiyama K, Yamada H, Hirano T
Chemico-biological interactions 2019 Sep 1;310:108726

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Astragaloside IV protects against hyperglycemia-induced vascular endothelial dysfunction by inhibiting oxidative stress and Calpain-1 activation.

Nie Q, Zhu L, Zhang L, Leng B, Wang H
Life sciences 2019 Sep 1;232:116662

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The protective effects of Ghrelin/GHSR on hippocampal neurogenesis in CUMS mice.

Huang HJ, Chen XR, Han QQ, Wang J, Pilot A, Yu R, Liu Q, Li B, Wu GC, Wang YQ, Yu J
Neuropharmacology 2019 Sep 1;155:31-43

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Grouper Atg12 negatively regulates the antiviral immune response against Singapore grouper iridovirus (SGIV) infection.

Li C, Yu Y, Zhang X, Wei J, Qin Q
Fish & shellfish immunology 2019 Oct;93:702-710

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MicroRNA-182-3p negatively regulates cytokines expression by targeting TLR5M in orange-spotted grouper, Epinephelus coioides.

He L, Zhao M, Yu X, Zhao Y, Fu L, Qiao X, Lin H, Zhang Y, Li G, Li S, Lu D
Fish & shellfish immunology 2019 Oct;93:589-596

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Naringin mitigates myocardial strain and the inflammatory response in sepsis-induced myocardial dysfunction through regulation of PI3K/AKT/NF-κB pathway.

Sun LJ, Qiao W, Xiao YJ, Cui L, Wang X, Ren WD
International immunopharmacology 2019 Oct;75:105782

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Rhein inhibits ATP-triggered inflammatory responses in rheumatoid rat fibroblast-like synoviocytes.

Hu F, Zhu D, Pei W, Lee I, Zhang X, Pan L, Xu J
International immunopharmacology 2019 Oct;75:105780

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SIRT1-regulated HMGB1 release is partially involved in TLR4 signal transduction: A possible anti-neuroinflammatory mechanism of resveratrol in neonatal hypoxic-ischemic brain injury.

Le K, Chibaatar Daliv E, Wu S, Qian F, Ali AI, Yu D, Guo Y
International immunopharmacology 2019 Oct;75:105779

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USP22 Deubiquitinates CD274 to Suppress Anticancer Immunity.

Huang X, Zhang Q, Lou Y, Wang J, Zhao X, Wang L, Zhang X, Li S, Zhao Y, Chen Q, Liang T, Bai X
Cancer immunology research 2019 Oct;7(10):1580-1590

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Overexpression of Limb-Bud and Heart (LBH) promotes angiogenesis in human glioma via VEGFA-mediated ERK signalling under hypoxia.

Jiang Y, Zhou J, Zou D, Hou D, Zhang H, Zhao J, Li L, Hu J, Zhang Y, Jing Z
EBioMedicine 2019 Oct;48:36-48

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MiR-26a promotes fracture healing of nonunion rats possibly by targeting SOSTDC1 and further activating Wnt/β-catenin signaling pathway.

Sun L, Li Z, Xue H, Ma T, Ren C, Li M, Lu Y, Sun H, Zhang K
Molecular and cellular biochemistry 2019 Oct;460(1-2):165-173

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Ginsenoside compound K ameliorates Alzheimer's disease in HT22 cells by adjusting energy metabolism.

Chen X, Li H, Yang Q, Lan X, Wang J, Cao Z, Shi X, Li J, Kan M, Qu X, Li N
Molecular biology reports 2019 Oct;46(5):5323-5332

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Dioscin attenuates Bleomycin-Induced acute lung injury via inhibiting the inflammatory response in mice.

Wu ZL, Wang J
Experimental lung research 2019 Oct;45(8):236-244

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Propentofylline reduces mechanical allodynia and induces mitogen-activated protein kinase phosphatase-1: An experimental study in a rat model of acute incisional pain.

Yang Y, Shi Y, Jia J, Wang S, Chang H, Li M, Jin X, Wang J
Neurological research 2019 Oct;41(10):900-908

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PM(2.5) upregulates rat mesenteric arteries 5-HT(2A) receptor via inflammatory-mediated mitogen-activated protein kinases signaling pathway.

Wang R, Cao L, Shen ZX, Cao YX, Yu J
Environmental toxicology 2019 Oct;34(10):1094-1104

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MYCT1 represses apoptosis of laryngeal cancerous cells through the MAX/miR-181a/NPM1 pathway.

Wang HT, Tong X, Zhang ZX, Sun YY, Yan W, Xu ZM, Fu WN
The FEBS journal 2019 Oct;286(19):3892-3908

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LncRNA ADPGK-AS1 regulated cell proliferation, invasion, migration and apoptosis via targeting miR-542-3p in osteosarcoma.

Luo XF, Wu XJ, Wei X, Wang AG, Wang SH, Wang JL
European review for medical and pharmacological sciences 2019 Oct;23(20):8751-8760

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Berberine attenuates XRCC1-mediated base excision repair and sensitizes breast cancer cells to the chemotherapeutic drugs.

Gao X, Wang J, Li M, Wang J, Lv J, Zhang L, Sun C, Ji J, Yang W, Zhao Z, Mao W
Journal of cellular and molecular medicine 2019 Oct;23(10):6797-6804

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Glycine cleavage system determines the fate of pluripotent stem cells via the regulation of senescence and epigenetic modifications.

Tian S, Feng J, Cao Y, Shen S, Cai Y, Yang D, Yan R, Wang L, Zhang H, Zhong X, Gao P
Life science alliance 2019 Oct;2(5)

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Cleavage and polyadenylation specific factor 4 promotes colon cancer progression by transcriptionally activating hTERT.

Yang Q, Fan W, Zheng Z, Lin S, Liu C, Wang R, Li W, Zuo Y, Sun Y, Hu S, Chen M, Guo P, Pan J, Tian C, Zhu T, Diao C, Hao J, Yu W, Li L, Li Y, Guo W, Deng W, Wu X
Biochimica et biophysica acta. Molecular cell research 2019 Oct;1866(10):1533-1543

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Apigenin reduces the excessive accumulation of lipids induced by palmitic acid via the AMPK signaling pathway in HepG2 cells.

Lu J, Meng Z, Cheng B, Liu M, Tao S, Guan S
Experimental and therapeutic medicine 2019 Oct;18(4):2965-2971

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The development of a cell-based model for the assessment of carcinogenic potential upon long-term PM2.5 exposure.

Chen S, Li D, Zhang H, Yu D, Chen R, Zhang B, Tan Y, Niu Y, Duan H, Mai B, Chen S, Yu J, Luan T, Chen L, Xing X, Li Q, Xiao Y, Dong G, Niu Y, Aschner M, Zhang R, Zheng Y, Chen W
Environment international 2019 Oct;131:104943

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Inhibition of myeloid differentiation 1 specifically in colon with antisense oligonucleotide exacerbates dextran sodium sulfate-induced colitis.

Chen X, Pan H, Li J, Zhang G, Cheng S, Zuo N, Zhao Q, Peng Z
Journal of cellular biochemistry 2019 Oct;120(10):16888-16899

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RNA sequencing analysis of the CAL-27 cell response to over-expressed ZNF750 gene revealed an extensive regulation on cell cycle.

Liu X, Yang Y, Xu C, Yang H, Chen S, Chen H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109377

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Limonin enhances the radiosensitivity of nasopharyngeal carcinoma cells via attenuating Stat3-induced cell stemness.

Gao L, Sang JZ, Cao H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109366

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SIRT1 activation attenuates cardiac fibrosis by endothelial-to-mesenchymal transition.

Liu ZH, Zhang Y, Wang X, Fan XF, Zhang Y, Li X, Gong YS, Han LP
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109227

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Inhibition of high mobility group box 1 (HMGB1) attenuates podocyte apoptosis and epithelial-mesenchymal transition by regulating autophagy flux.

Jin J, Gong J, Zhao L, Zhang H, He Q, Jiang X
Journal of diabetes 2019 Oct;11(10):826-836

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MiR-16a Regulates Milk Fat Metabolism by Targeting Large Tumor Suppressor Kinase 1 (LATS1) in Bovine Mammary Epithelial Cells.

Chen Z, Chu S, Wang X, Sun Y, Xu T, Mao Y, Loor JJ, Yang Z
Journal of agricultural and food chemistry 2019 Oct 9;67(40):11167-11178

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Viral N(6)-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus.

Xue M, Zhao BS, Zhang Z, Lu M, Harder O, Chen P, Lu Z, Li A, Ma Y, Xu Y, Liang X, Zhou J, Niewiesk S, Peeples ME, He C, Li J
Nature communications 2019 Oct 9;10(1):4595

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CircWHSC1 promotes ovarian cancer progression by regulating MUC1 and hTERT through sponging miR-145 and miR-1182.

Zong ZH, Du YP, Guan X, Chen S, Zhao Y
Journal of experimental & clinical cancer research : CR 2019 Oct 30;38(1):437

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Oxidative stress-induced cellular senescence desensitizes cell growth and migration of vascular smooth muscle cells through down-regulation of platelet-derived growth factor receptor-beta.

Pan CH, Chen CJ, Shih CM, Wang MF, Wang JY, Wu CH
Aging 2019 Oct 3;11(19):8085-8102

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Tumor vasculature remolding by thalidomide increases delivery and efficacy of cisplatin.

Shen Y, Li S, Wang X, Wang M, Tian Q, Yang J, Wang J, Wang B, Liu P, Yang J
Journal of experimental & clinical cancer research : CR 2019 Oct 28;38(1):427

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Knockout of neutrophil elastase protects against western diet induced nonalcoholic steatohepatitis in mice by regulating hepatic ceramides metabolism.

Chen J, Liang B, Bian D, Luo Y, Yang J, Li Z, Zhuang Z, Zang S, Shi J
Biochemical and biophysical research communications 2019 Oct 22;518(4):691-697

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SPOP suppresses pancreatic cancer progression by promoting the degradation of NANOG.

Tan P, Xu Y, Du Y, Wu L, Guo B, Huang S, Zhu J, Li B, Lin F, Yao L
Cell death & disease 2019 Oct 17;10(11):794

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Circ-Spidr enhances axon regeneration after peripheral nerve injury.

Mao S, Huang T, Chen Y, Shen L, Zhou S, Zhang S, Yu B
Cell death & disease 2019 Oct 17;10(11):787

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γ-Oryzanol alleviates acetaminophen-induced liver injury: roles of modulating AMPK/GSK3β/Nrf2 and NF-κB signaling pathways.

Shu G, Qiu Y, Hao J, Fu Q, Deng X
Food & function 2019 Oct 16;10(10):6858-6872

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Six1 is negatively correlated with poor prognosis and reduces 5-fluorouracil sensitivity via attenuating the stemness of hepatocellular carcinoma cells.

Chen K, Wei H, Pan J, Chen Z, Pan D, Gao T, Huang J, Huang M, Ou M, Zhong W
European journal of pharmacology 2019 Oct 15;861:172599

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Angiotensin II deteriorates advanced atherosclerosis by promoting MerTK cleavage and impairing efferocytosis through the AT(1)R/ROS/p38 MAPK/ADAM17 pathway.

Zhang Y, Wang Y, Zhou D, Zhang LS, Deng FX, Shu S, Wang LJ, Wu Y, Guo N, Zhou J, Yuan ZY
American journal of physiology. Cell physiology 2019 Oct 1;317(4):C776-C787

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Melatonin Receptor Mel1b- and Mel1c-mediated Green Light Induced the Secretion of Growth Hormone in Anterior Pituitary of Chicks.

Yue L, Qin X, Liu X, Wang Z, Dong Y, Chen Y, Cao J
Photochemistry and photobiology 2019 Nov;95(6):1387-1394

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A novel RING finger protein CqRNF152-like with self-ubiquitination activity inhibits white spot syndrome virus infection in a crustacean Cherax quadricarinatus.

Zheng SC, Chang XJ, Li WD, Wang H, Guo LM, Wang KJ, Liu HP
Fish & shellfish immunology 2019 Nov;94:934-943

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Zinc alleviates arsenism in common carp: Varied change profiles of cytokines and tight junction proteins among two intestinal segments.

Zhao H, Wang Y, Yang X, Fei D, Mu M, Guo M, Yu H, Xing M
Fish & shellfish immunology 2019 Nov;94:761-768

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Molecular cloning, expression and functional analysis of Atg16L1 from orange-spotted grouper (Epinephelus coioides).

Li C, Wang L, Zhang X, Wei J, Qin Q
Fish & shellfish immunology 2019 Nov;94:113-121

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Screening candidate microR-15a- IRAK2 regulatory pairs for predicting the response to Staphylococcus aureus-induced mastitis in dairy cows.

Chen Z, Zhou J, Wang X, Zhang Y, Lu X, Fan Y, Mao Y, Loor JJ, Yang Z
The Journal of dairy research 2019 Nov;86(4):425-431

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Tumor-suppressive activity of Hnf1β in Wilms' tumor.

Liu Y, Kanyomse Q, Xie Y
Bioscience, biotechnology, and biochemistry 2019 Nov;83(11):2008-2015

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The protective effects of L-carnitine on myocardial ischaemia-reperfusion injury in patients with rheumatic valvular heart disease undergoing CPB surgery are associated with the suppression of NF-κB pathway and the activation of Nrf2 pathway.

Li M, Xu S, Geng Y, Sun L, Wang R, Yan Y, Wang H, Li Y, Yi Q, Zhang Y, Hao J, Deng C, Li W, Xue L
Clinical and experimental pharmacology & physiology 2019 Nov;46(11):1001-1012

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ADP-ribosyltransferase PARP11 modulates the interferon antiviral response by mono-ADP-ribosylating the ubiquitin E3 ligase β-TrCP.

Guo T, Zuo Y, Qian L, Liu J, Yuan Y, Xu K, Miao Y, Feng Q, Chen X, Jin L, Zhang L, Dong C, Xiong S, Zheng H
Nature microbiology 2019 Nov;4(11):1872-1884

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Nonviral Delivery of GRIM-19 Gene Inhibits Tumor Growth with Reduced Local and Systemic Complications.

Xu Y, Wang X, Guo B, Wang D, Kalvakolanu DV, Chen X, Tang J, Zhang L, Yang Q
Human gene therapy 2019 Nov;30(11):1419-1430

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Long-term exposure of 4-hydroxyestradiol induces the cancer cell characteristics via upregulating CYP1B1 in MCF-10A cells.

Lanxiang W, Bin W, Ge X, Yutang H, Chunjie W, Honghao Z
Toxicology mechanisms and methods 2019 Nov;29(9):686-692

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Isoflurane produces antidepressant effects inducing BDNF-TrkB signaling in CUMS mice.

Zhang SS, Tian YH, Jin SJ, Wang WC, Zhao JX, Si XM, Zhang L, Xu H, Jin JY
Psychopharmacology 2019 Nov;236(11):3301-3315

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Astragaloside IV alleviates myocardial damage induced by type 2 diabetes via improving energy metabolism.

Zhang Z, Wang J, Zhu Y, Zhang H, Wang H
Molecular medicine reports 2019 Nov;20(5):4612-4622

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Deep Protein Methylation Profiling by Combined Chemical and Immunoaffinity Approaches Reveals Novel PRMT1 Targets.

Hartel NG, Chew B, Qin J, Xu J, Graham NA
Molecular & cellular proteomics : MCP 2019 Nov;18(11):2149-2164

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Repurposing of the anti-helminthic drug niclosamide to treat melanoma and pulmonary metastasis via the STAT3 signaling pathway.

Zhu Y, Zuo W, Chen L, Bian S, Jing J, Gan C, Wu X, Liu H, Su X, Hu W, Guo Y, Wang Y, Ye T
Biochemical pharmacology 2019 Nov;169:113610

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Increased Tim-3 expression alleviates liver injury by regulating macrophage activation in MCD-induced NASH mice.

Du X, Wu Z, Xu Y, Liu Y, Liu W, Wang T, Li C, Zhang C, Yi F, Gao L, Liang X, Ma C
Cellular & molecular immunology 2019 Nov;16(11):878-886

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LNRRIL6, a novel long noncoding RNA, protects colorectal cancer cells by activating the IL-6-STAT3 pathway.

Wang J, Zhou J, Jiang C, Zheng J, Namba H, Chi P, Asakawa T
Molecular oncology 2019 Nov;13(11):2344-2360

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Inhibition of p53 and/or AKT as a new therapeutic approach specifically targeting ALT cancers.

Ge Y, Wu S, Zhang Z, Li X, Li F, Yan S, Liu H, Huang J, Zhao Y
Protein & cell 2019 Nov;10(11):808-824

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O-GlcNAcylation of Thr(12)/Ser(56) in short-form O-GlcNAc transferase (sOGT) regulates its substrate selectivity.

Liu L, Li L, Ma C, Shi Y, Liu C, Xiao Z, Zhang Y, Tian F, Gao Y, Zhang J, Ying W, Wang PG, Zhang L
The Journal of biological chemistry 2019 Nov 8;294(45):16620-16633

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LncRNA GABPB1-AS1 and GABPB1 regulate oxidative stress during erastin-induced ferroptosis in HepG2 hepatocellular carcinoma cells.

Qi W, Li Z, Xia L, Dai J, Zhang Q, Wu C, Xu S
Scientific reports 2019 Nov 7;9(1):16185

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Porcine Circovirus Type 2 Induces Single Immunoglobulin Interleukin-1 Related Receptor (SIGIRR) Downregulation to Promote Interleukin-1β Upregulation in Porcine Alveolar Macrophage.

Yang S, Liu B, Yin S, Shang Y, Zhang X, Khan MUZ, Liu X, Cai J
Viruses 2019 Nov 3;11(11)

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Dietary Stevioside Supplementation Alleviates Lipopolysaccharide-Induced Intestinal Mucosal Damage through Anti-Inflammatory and Antioxidant Effects in Broiler Chickens.

Jiang J, Qi L, Lv Z, Jin S, Wei X, Shi F
Antioxidants (Basel, Switzerland) 2019 Nov 21;8(12)

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Mulberry leaf reduces inflammation and insulin resistance in type 2 diabetic mice by TLRs and insulin Signalling pathway.

Tian S, Wang M, Liu C, Zhao H, Zhao B
BMC complementary and alternative medicine 2019 Nov 21;19(1):326

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Inhibition of PTP1B blocks pancreatic cancer progression by targeting the PKM2/AMPK/mTOC1 pathway.

Xu Q, Wu N, Li X, Guo C, Li C, Jiang B, Wang H, Shi D
Cell death & disease 2019 Nov 19;10(12):874

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Self-Assembled saRNA Delivery System Based on Rolling Circle Transcription for Aptamer-Targeting Cancer Therapy.

Wang T, Hong S, Luo Y, Lv H, Zhang Y, Pei R
ACS applied bio materials 2019 Nov 18;2(11):4737-4746

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Tissue plasminogen activator disrupts the blood-brain barrier through increasing the inflammatory response mediated by pericytes after cerebral ischemia.

Yang E, Cai Y, Yao X, Liu J, Wang Q, Jin W, Wu Q, Fan W, Qiu L, Kang C, Wu J
Aging 2019 Nov 18;11(22):10167-10182

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Chitosan Oligosaccharide Attenuates Nonalcoholic Fatty Liver Disease Induced by High Fat Diet through Reducing Lipid Accumulation, Inflammation and Oxidative Stress in C57BL/6 Mice.

Tao W, Sun W, Liu L, Wang G, Xiao Z, Pei X, Wang M
Marine drugs 2019 Nov 16;17(11)

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Cardioprotective effects of galectin-3 inhibition against ischemia/reperfusion injury.

Mo D, Tian W, Zhang HN, Feng YD, Sun Y, Quan W, Hao XW, Wang XY, Liu XX, Li C, Cao W, Liu WJ, Li XQ
European journal of pharmacology 2019 Nov 15;863:172701

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Anti-osteoporosis effects of osteoking via reducing reactive oxygen species.

Qin D, Zhang H, Zhang H, Sun T, Zhao H, Lee WH
Journal of ethnopharmacology 2019 Nov 15;244:112045

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Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications.

Ward CC, Kleinman JI, Brittain SM, Lee PS, Chung CYS, Kim K, Petri Y, Thomas JR, Tallarico JA, McKenna JM, Schirle M, Nomura DK
ACS chemical biology 2019 Nov 15;14(11):2430-2440

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Epithelial and interstitial Notch1 activity contributes to the myofibroblastic phenotype and fibrosis.

Hong W, Zhang G, Lu H, Guo Y, Zheng S, Zhu H, Xiao Y, Papa APD, Wu C, Sun L, Chen B, Bai Y
Cell communication and signaling : CCS 2019 Nov 12;17(1):145

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Dengue Virus M Protein Promotes NLRP3 Inflammasome Activation To Induce Vascular Leakage in Mice.

Pan P, Zhang Q, Liu W, Wang W, Lao Z, Zhang W, Shen M, Wan P, Xiao F, Liu F, Zhang W, Tan Q, Liu X, Wu K, Liu Y, Li G, Wu J
Journal of virology 2019 Nov 1;93(21)

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Epigenetic Memory Is Involved in the Persistent Alterations of Drug-Processing Genes in Adult Mice Due to PCN-Activated PXR During Early Life.

Wang P, Liu G, Nie Y, Han S, Li J, Zhong XB, Zhang L
Toxicological sciences : an official journal of the Society of Toxicology 2019 Nov 1;172(1):98-108

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Recombinant porcine NK-lysin inhibits the invasion of hepatocellular carcinoma cells in vitro.

Khan A, Fan K, Sun N, Yin W, Sun Y, Sun P, Jahejo AR, Li H
International journal of biological macromolecules 2019 Nov 1;140:1249-1259

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Hepatocyte nuclear factor 1 alpha (HNF1A) regulates transcription of O-GlcNAc transferase in a negative feedback mechanism.

Zhang C, Xie F, Li L, Zhang C, Zhang Y, Ying W, Liu L, Yan X, Yin F, Zhang L
FEBS letters 2019 May;593(10):1050-1060

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Degradation of Caytaxin Causes Learning and Memory Deficits via Activation of DAPK1 in Aging.

Guo Y, Li H, Ke X, Deng M, Wu Z, Cai Y, Afewerky HK, Zhang X, Pei L, Lu Y
Molecular neurobiology 2019 May;56(5):3368-3379

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ZW290 Increases Cold Tolerance by Inducing Thermogenesis via the Upregulation of Uncoupling Protein 1 in Brown Adipose Tissue In Vitro and In Vivo.

Wang N, Lu HY, Li X, Du YJ, Meng WH, Ding HW, Zhao QC
Lipids 2019 May;54(5):265-276

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Inhibition of PI3K/mTOR increased the sensitivity of hepatocellular carcinoma cells to cisplatin via interference with mitochondrial-lysosomal crosstalk.

Sheng J, Shen L, Sun L, Zhang X, Cui R, Wang L
Cell proliferation 2019 May;52(3):e12609

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Homeodomain-interacting protein kinase 2 suppresses proliferation and aerobic glycolysis via ERK/cMyc axis in pancreatic cancer.

Qin Y, Hu Q, Ji S, Xu J, Dai W, Liu W, Xu W, Sun Q, Zhang Z, Ni Q, Yu X, Zhang B, Xu X
Cell proliferation 2019 May;52(3):e12603

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Moderate- and Low-Dose of Atorvastatin Alleviate Cognition Impairment Induced by High-Fat Diet via Sirt1 Activation.

Liu H, Yang J, Wang K, Niu T, Huang D
Neurochemical research 2019 May;44(5):1065-1078

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Apoptosis and cell cycle arrest of hepatocellular carcinoma spheroids treated by an alternating electric field.

Huang CH, Lei KF, Tsang NM
Biotechnology progress 2019 May;35(3):e2787

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[6]-Gingerol enhances the cisplatin sensitivity of gastric cancer cells through inhibition of proliferation and invasion via PI3K/AKT signaling pathway.

Luo Y, Zha L, Luo L, Chen X, Zhang Q, Gao C, Zhuang X, Yuan S, Qiao T
Phytotherapy research : PTR 2019 May;33(5):1353-1362

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5-aminolevulinic acid photodynamic therapy reduces HPV viral load via autophagy and apoptosis by modulating Ras/Raf/MEK/ERK and PI3K/AKT pathways in HeLa cells.

Xie J, Wang S, Li Z, Ao C, Wang J, Wang L, Peng X, Zeng K
Journal of photochemistry and photobiology. B, Biology 2019 May;194:46-55

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A novel function of anaphase promoting complex subunit 10 in tumor progression in non-small cell lung cancer.

Wang Y, Han T, Gan M, Guo M, Xie C, Jin J, Zhang S, Wang P, Cao J, Wang JB
Cell cycle (Georgetown, Tex.) 2019 May;18(9):1019-1032

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Nano hydroxyapatite induces glioma cell apoptosis by suppressing NF-κB signaling pathway.

Guo G, Tian A, Lan X, Fu C, Yan Z, Wang C
Experimental and therapeutic medicine 2019 May;17(5):4080-4088

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Porcine circovirus type 2 ORF5 protein induces endoplasmic reticulum stress and unfolded protein response in porcine alveolar macrophages.

Ouyang Y, Xu L, Lv J, Hou Y, Fan Z, Xu P, Jiang Y, Wu M, Li R, Zhang Y, Guo K
Archives of virology 2019 May;164(5):1323-1334

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TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response.

Wang P, Deng J, Dong J, Liu J, Bigio EH, Mesulam M, Wang T, Sun L, Wang L, Lee AY, McGee WA, Chen X, Fushimi K, Zhu L, Wu JY
PLoS genetics 2019 May;15(5):e1007947

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Heat shock factor 1 in cancer-associated fibroblasts is a potential prognostic factor and drives progression of oral squamous cell carcinoma.

Wang Q, Zhang YC, Zhu LF, Pan L, Yu M, Shen WL, Li B, Zhang W, Liu LK
Cancer science 2019 May;110(5):1790-1803

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LncRNA TPT1-AS1 promotes tumorigenesis and metastasis in epithelial ovarian cancer by inducing TPT1 expression.

Wu W, Gao H, Li X, Zhu Y, Peng S, Yu J, Zhan G, Wang J, Liu N, Guo X
Cancer science 2019 May;110(5):1587-1598

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Highly Selective Protein Tyrosine Phosphatase Inhibitor, 2,2',3,3'-Tetrabromo-4,4',5,5'-tetrahydroxydiphenylmethane, Ameliorates Type 2 Diabetes Mellitus in BKS db Mice.

Li C, Luo J, Guo S, Jia X, Guo C, Li X, Xu Q, Shi D
Molecular pharmaceutics 2019 May 6;16(5):1839-1850

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Adipose HuR protects against diet-induced obesity and insulin resistance.

Li J, Gong L, Liu S, Zhang Y, Zhang C, Tian M, Lu H, Bu P, Yang J, Ouyang C, Jiang X, Wu J, Zhang Y, Min Q, Zhang C, Zhang W
Nature communications 2019 May 30;10(1):2375

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Canagliflozin inhibits growth of hepatocellular carcinoma via blocking glucose-influx-induced β-catenin activation.

Hung MH, Chen YL, Chen LJ, Chu PY, Hsieh FS, Tsai MH, Shih CT, Chao TI, Huang CY, Chen KF
Cell death & disease 2019 May 29;10(6):420

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Fucoidan A2 from the Brown Seaweed Ascophyllum nodosum Lowers Lipid by Improving Reverse Cholesterol Transport in C57BL/6J Mice Fed a High-Fat Diet.

Yang Z, Liu G, Wang Y, Yin J, Wang J, Xia B, Li T, Yang X, Hou P, Hu S, Song W, Guo S
Journal of agricultural and food chemistry 2019 May 22;67(20):5782-5791

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Estrogen negatively regulates the renal epithelial sodium channel (ENaC) by promoting Derlin-1 expression and AMPK activation.

Zhang X, Ge Y, Bukhari AA, Zhu Q, Shen Y, Li M, Sun H, Su D, Liang X
Experimental & molecular medicine 2019 May 21;51(5):1-12

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Phosphatase of regenerating liver sensitizes MET to functional activation by hepatocyte growth factor.

Kojima T, Funato Y, Miki H
The Biochemical journal 2019 May 21;476(10):1419-1431

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Triptolide prevents proliferation and migration of Esophageal Squamous Cell Cancer via MAPK/ERK signaling pathway.

Yanchun M, Yi W, Lu W, Yu Q, Jian Y, Pengzhou K, Ting Y, Hongyi L, Fang W, Xiaolong C, Yongping C
European journal of pharmacology 2019 May 15;851:43-51

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Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs.

Jia YN, Peng YL, Zhao YP, Cheng XF, Zhou Y, Chai CL, Zeng LS, Pan MH, Xu L
Journal of agricultural and food chemistry 2019 May 15;67(19):5521-5529

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MiR-34s negatively regulate homologous recombination through targeting RAD51.

Chen S, Liu R, Wang Q, Qi Z, Hu Y, Zhou P, Wang Z
Archives of biochemistry and biophysics 2019 May 15;666:73-82

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Gambogic acid attenuates liver fibrosis by inhibiting the PI3K/AKT and MAPK signaling pathways via inhibiting HSP90.

Yu Z, Jv Y, Cai L, Tian X, Huo X, Wang C, Zhang B, Sun C, Ning J, Feng L, Zhang H, Ma X
Toxicology and applied pharmacology 2019 May 15;371:63-73

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Meningitic Escherichia coli-induced upregulation of PDGF-B and ICAM-1 aggravates blood-brain barrier disruption and neuroinflammatory response.

Yang RC, Qu XY, Xiao SY, Li L, Xu BJ, Fu JY, Lv YJ, Amjad N, Tan C, Kim KS, Chen HC, Wang XR
Journal of neuroinflammation 2019 May 15;16(1):101

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Sodium ferulate protects against influenza virus infection by activation of the TLR7/9-MyD88-IRF7 signaling pathway and inhibition of the NF-κB signaling pathway.

Zhu Y, Shao Y, Qu X, Guo J, Yang J, Zhou Z, Wang S
Biochemical and biophysical research communications 2019 May 14;512(4):793-798

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A maternal high-fat, high-sucrose diet induces transgenerational cardiac mitochondrial dysfunction independently of maternal mitochondrial inheritance.

Ferey JLA, Boudoures AL, Reid M, Drury A, Scheaffer S, Modi Z, Kovacs A, Pietka T, DeBosch BJ, Thompson MD, Diwan A, Moley KH
American journal of physiology. Heart and circulatory physiology 2019 May 1;316(5):H1202-H1210

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Histone deacetylase 7 inhibits plakoglobin expression to promote lung cancer cell growth and metastasis.

Sang Y, Sun L, Wu Y, Yuan W, Liu Y, Li SW
International journal of oncology 2019 Mar;54(3):1112-1122

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Overexpression of ERBB4 rejuvenates aged mesenchymal stem cells and enhances angiogenesis via PI3K/AKT and MAPK/ERK pathways.

Liang X, Ding Y, Lin F, Zhang Y, Zhou X, Meng Q, Lu X, Jiang G, Zhu H, Chen Y, Lian Q, Fan H, Liu Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Mar;33(3):4559-4570

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In utero exposure to PM2.5 during gestation caused adult cardiac hypertrophy through histone acetylation modification.

Wu X, Pan B, Liu L, Zhao W, Zhu J, Huang X, Tian J
Journal of cellular biochemistry 2019 Mar;120(3):4375-4384

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Nuciferine inhibits the progression of glioblastoma by suppressing the SOX2-AKT/STAT3-Slug signaling pathway.

Li Z, Chen Y, An T, Liu P, Zhu J, Yang H, Zhang W, Dong T, Jiang J, Zhang Y, Jiang M, Yang X
Journal of experimental & clinical cancer research : CR 2019 Mar 29;38(1):139

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Cysteine Dioxygenase Regulates the Epithelial Morphogenesis of Mammary Gland via Cysteine Sulfinic Acid.

Zhao J, Han Y, Ma X, Zhou Y, Yuan S, Shen Q, Ye G, Liu H, Fu P, Zhang G, Qiao B, Liu A
iScience 2019 Mar 29;13:173-189

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The nanoparticle-facilitated autophagy inhibition of cancer stem cells for improved chemotherapeutic effects on glioblastomas.

Lu L, Shen X, Tao B, Lin C, Li K, Luo Z, Cai K
Journal of materials chemistry. B 2019 Mar 28;7(12):2054-2062

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Curcumin and Resveratrol Regulate Intestinal Bacteria and Alleviate Intestinal Inflammation in Weaned Piglets.

Gan Z, Wei W, Li Y, Wu J, Zhao Y, Zhang L, Wang T, Zhong X
Molecules (Basel, Switzerland) 2019 Mar 28;24(7)

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Effect of Stereochemical Configuration on the Transport and Metabolism of Catechins from Green Tea across Caco-2 Monolayers.

Ai Z, Liu S, Qu F, Zhang H, Chen Y, Ni D
Molecules (Basel, Switzerland) 2019 Mar 26;24(6)

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RNA-Binding Motif Protein 24 (RBM24) Is Involved in Pregenomic RNA Packaging by Mediating Interaction between Hepatitis B Virus Polymerase and the Epsilon Element.

Yao Y, Yang B, Chen Y, Wang H, Hu X, Zhou Y, Gao X, Lu M, Niu J, Wen Z, Wu C, Chen X
Journal of virology 2019 Mar 15;93(6)

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GRASP depletion-mediated Golgi destruction decreases cell adhesion and migration via the reduction of α5β1 integrin.

Ahat E, Xiang Y, Zhang X, Bekier ME 2nd, Wang Y
Molecular biology of the cell 2019 Mar 15;30(6):766-777

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The role of adenosine in up-regulation of p38 MAPK and ERK during limb ischemic preconditioning-induced brain ischemic tolerance.

Yuan Q, Jia HX, Li SQ, Xiao-Zhang, Wu YJ, Feng L, Liu XL, Sun XC, Li WB
Brain research 2019 Mar 15;1707:172-183

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Purification of cross-linked RNA-protein complexes by phenol-toluol extraction.

Urdaneta EC, Vieira-Vieira CH, Hick T, Wessels HH, Figini D, Moschall R, Medenbach J, Ohler U, Granneman S, Selbach M, Beckmann BM
Nature communications 2019 Mar 1;10(1):990

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CD30 ligand deficiency accelerates glioma progression by promoting the formation of tumor immune microenvironment.

Duan J, Gao Y, Zhang X, Wang X, Wang B, Meng X, Yoshikai Y, Wang Y, Sun X
International immunopharmacology 2019 Jun;71:350-360

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Deficiency of ZnT8 Promotes Adiposity and Metabolic Dysfunction by Increasing Peripheral Serotonin Production.

Mao Z, Lin H, Su W, Li J, Zhou M, Li Z, Zhou B, Yang Q, Zhou M, Pan K, He J, Zhang W
Diabetes 2019 Jun;68(6):1197-1209

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MicroRNA-145 regulates immune cytokines via targeting FSCN1 in Staphylococcus aureus-induced mastitis in dairy cows.

Chen Z, Xu X, Tan T, Chen D, Liang H, Sun K, Li M, Zhang H, Mao Y, Yang Z
Reproduction in domestic animals = Zuchthygiene 2019 Jun;54(6):882-891

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ERβ modulates genistein's cisplatin-enhancing activities in breast cancer MDA-MB-231 cells via P53-independent pathway.

Liu R, Xu X, Liang C, Chen X, Yu X, Zhong H, Xu W, Cheng Y, Wang W, Wu Y, Yu L, Hu X
Molecular and cellular biochemistry 2019 Jun;456(1-2):205-216

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B-lymphocyte-intrinsic and -extrinsic defects in secretory immunoglobulin A production in the neural crest-conditional deletion of endothelin receptor B model of Hirschsprung-associated enterocolitis.

Medrano G, Cailleux F, Guan P, Kuruvilla K, Barlow-Anacker AJ, Gosain A
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jun;33(6):7615-7624

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p62 aggregates mediated Caspase 8 activation is responsible for progression of ovarian cancer.

Yan XY, Zhong XR, Yu SH, Zhang LC, Liu YN, Zhang Y, Sun LK, Su J
Journal of cellular and molecular medicine 2019 Jun;23(6):4030-4042

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Age-dependent expression of the vitamin D receptor and the protective effect of vitamin D receptor activation on H(2)O(2)-induced apoptosis in rat intervertebral disc cells.

Tong T, Liu Z, Zhang H, Sun J, Zhang D, Wang F, Miao D, Shen Y
The Journal of steroid biochemistry and molecular biology 2019 Jun;190:126-138

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TUSC3 as a potential biomarker for prognosis in clear cell renal cell carcinoma.

Yan Y, Chen Z, Liao Y, Zhou J
Oncology letters 2019 Jun;17(6):5073-5079

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An NLRP3 inflammasome-triggered cytokine storm contributes to Streptococcal toxic shock-like syndrome (STSLS).

Lin L, Xu L, Lv W, Han L, Xiang Y, Fu L, Jin M, Zhou R, Chen H, Zhang A
PLoS pathogens 2019 Jun;15(6):e1007795

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Decreased S1P and SPHK2 are involved in pancreatic acinar cell injury.

Xiao J, Lin H, Liu B, Xia Z, Zhang J, Jin J
Biomarkers in medicine 2019 Jun;13(8):627-637

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A promising therapeutic option for diabetic bladder dysfunction: Adipose tissue-derived stem cells pretreated by defocused low-energy shock wave.

Zhang H, Zhao Y, Wang M, Song W, Sun P, Jin X
Journal of tissue engineering and regenerative medicine 2019 Jun;13(6):986-996

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High-level expression of PRSS3 correlates with metastasis and poor prognosis in patients with gastric cancer.

Wang F, Hu YL, Feng Y, Guo YB, Liu YF, Mao QS, Xue WJ
Journal of surgical oncology 2019 Jun;119(8):1108-1121

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Recombinant human arginase I elicited immunosuppression in activated macrophages through inhibiting autophagy.

Wang Z, Song P, Li Y, Wang S, Fan J, Zhang X, Luan J, Chen W, Wang Y, Liu P, Ju D
Applied microbiology and biotechnology 2019 Jun;103(12):4825-4838

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Rh type C-glycoprotein functions as a novel tumor suppressor gene by inhibiting tumorigenicity and metastasis in head and neck squamous cell carcinoma.

Xu W, Zou H, Wei Z, Song C, Tang C, Yin X, Wang Y, Han S, Cai Y, Han W
Aging 2019 Jun 6;11(11):3601-3623

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Mechanism of Snhg8/miR-384/Hoxa13/FAM3A axis regulating neuronal apoptosis in ischemic mice model.

Liu J, An P, Xue Y, Che D, Liu X, Zheng J, Liu Y, Yang C, Li Z, Yu B
Cell death & disease 2019 Jun 5;10(6):441

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ROS/JNK/c-Jun axis is involved in oridonin-induced caspase-dependent apoptosis in human colorectal cancer cells.

Zhang D, Zhou Q, Huang D, He L, Zhang H, Hu B, Peng H, Ren D
Biochemical and biophysical research communications 2019 Jun 4;513(3):594-601

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TGF-β mediates thoracic radiation-induced abscopal effects of testis injury in rat.

Zhang J, Yao D, Zhang J, Song Y, Mo F, Chu X, Pan Y, Bai Y, Shao C
Biochemical and biophysical research communications 2019 Jun 30;514(3):678-683

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Chitosan Hydrogel Delivery System Containing Herbal Compound Functions as a Potential Antineuroinflammatory Agent.

Zhou J, Zheng J, Zhang Y, Zheng P, Tang T, Luo JK, Cui HJ, Song RR, Wang Y
ACS omega 2019 Jun 30;4(6):10185-10191

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UHRF1 promotes aerobic glycolysis and proliferation via suppression of SIRT4 in pancreatic cancer.

Hu Q, Qin Y, Ji S, Xu W, Liu W, Sun Q, Zhang Z, Liu M, Ni Q, Yu X, Xu X
Cancer letters 2019 Jun 28;452:226-236

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TRIP4 promotes tumor growth and metastasis and regulates radiosensitivity of cervical cancer by activating MAPK, PI3K/AKT, and hTERT signaling.

Che Y, Li Y, Zheng F, Zou K, Li Z, Chen M, Hu S, Tian C, Yu W, Guo W, Luo M, Deng W, Zou L
Cancer letters 2019 Jun 28;452:1-13

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Silencing of Aberrant Secretory Protein Expression by Disease-Associated Mutations.

Tikhonova EB, Karamysheva ZN, von Heijne G, Karamyshev AL
Journal of molecular biology 2019 Jun 28;431(14):2567-2580

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Organophosphorus Flame Retardants Impair Intracellular Lipid Metabolic Function in Human Hepatocellular Cells.

Hao Z, Zhang Z, Lu D, Ding B, Shu L, Zhang Q, Wang C
Chemical research in toxicology 2019 Jun 17;32(6):1250-1258

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Blocking podoplanin suppresses growth and pulmonary metastasis of human malignant melanoma.

Xu M, Wang X, Pan Y, Zhao X, Yan B, Ruan C, Xia L, Zhao Y
BMC cancer 2019 Jun 17;19(1):599

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Insulin transcriptionally down-regulates carboxylesterases through pregnane X receptor in an Akt-dependent manner.

Yang X, Zhang X, Liu Y, Xi T, Xiong J
Toxicology 2019 Jun 15;422:60-68

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Inhibition of Glioma Development by ASCL1-Mediated Direct Neuronal Reprogramming.

Cheng X, Tan Z, Huang X, Yuan Y, Qin S, Gu Y, Wang D, He C, Su Z
Cells 2019 Jun 11;8(6)

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Porcine HMGCR Inhibits Porcine Circovirus Type 2 Infection by Directly Interacting with the Viral Proteins.

Ouyang T, Niu G, Zhang Y, Liu X, Zhang X, Zhang S, Geng Y, Pang D, Ouyang H, Ren L
Viruses 2019 Jun 11;11(6)

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Sonodynamic therapy inhibits palmitate-induced beta cell dysfunction via PINK1/Parkin-dependent mitophagy.

Guo T, Liu T, Sun Y, Liu X, Xiong R, Li H, Li Z, Zhang Z, Tian Z, Tian Y
Cell death & disease 2019 Jun 11;10(6):457

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Macrophage Migration Inhibitory Factor Promotes Chemotaxis of Astrocytes through Regulation of Cholesterol 25-Hydroxylase Following Rat Spinal Cord Injury.

Zhu Z, Hu Y, Zhou Y, Zhang Y, Yu L, Tao L, Guo A, Fang Q
Neuroscience 2019 Jun 1;408:349-360

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A new split-luciferase complementation assay identifies pentachlorophenol as an inhibitor of apoptosome formation.

Tashakor A, H-Dehkordi M, O'Connell E, Gomez Ganau S, Gozalbes R, Eriksson LA, Hosseinkhani S, Fearnhead HO
FEBS open bio 2019 Jul;9(7):1194-1203

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Activation of the immunoproteasome protects SH-SY5Y cells from the toxicity of rotenone.

Sun C, Mo M, Wang Y, Yu W, Song C, Wang X, Chen S, Liu Y
Neurotoxicology 2019 Jul;73:112-119

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Atractylodin ameliorates lipopolysaccharide and d-galactosamine-induced acute liver failure via the suppression of inflammation and oxidative stress.

Lyu Z, Ji X, Chen G, An B
International immunopharmacology 2019 Jul;72:348-357

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MicroRNA-221 sensitizes chronic myeloid leukemia cells to imatinib by targeting STAT5.

Jiang X, Cheng Y, Hu C, Zhang A, Ren Y, Xu X
Leukemia & lymphoma 2019 Jul;60(7):1709-1720

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Epithelial ovarian cancer stem‑like cells are resistant to the cellular lysis of cytokine‑induced killer cells via HIF1A‑mediated downregulation of ICAM‑1.

Bu S, Li B, Wang Q, Gu T, Dong Q, Miao X, Lai D
International journal of oncology 2019 Jul;55(1):179-190

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Aspirin targets P4HA2 through inhibiting NF-κB and LMCD1-AS1/let-7g to inhibit tumour growth and collagen deposition in hepatocellular carcinoma.

Wang T, Fu X, Jin T, Zhang L, Liu B, Wu Y, Xu F, Wang X, Ye K, Zhang W, Ye L
EBioMedicine 2019 Jul;45:168-180

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Tubeimoside-1, a triterpenoid saponin, induces cytoprotective autophagy in human breast cancer cells in vitro via Akt-mediated pathway.

Jiang SL, Guan YD, Chen XS, Ge P, Wang XL, Lao YZ, Xiao SS, Zhang Y, Yang JM, Xu XJ, Cao DS, Cheng Y
Acta pharmacologica Sinica 2019 Jul;40(7):919-928

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Septin 9 isoforms promote tumorigenesis in mammary epithelial cells by increasing migration and ECM degradation through metalloproteinase secretion at focal adhesions.

Marcus J, Bejerano-Sagie M, Patterson N, Bagchi S, Verkhusha VV, Connolly D, Goldberg GL, Golden A, Sharma VP, Condeelis J, Montagna C
Oncogene 2019 Jul;38(30):5839-5859

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STAT3 phosphorylation mediates high glucose-impaired cell autophagy in an HDAC1-dependent and -independent manner in Schwann cells of diabetic peripheral neuropathy.

Du W, Wang N, Li F, Jia K, An J, Liu Y, Wang Y, Zhu L, Zhao S, Hao J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jul;33(7):8008-8021

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Notch signaling activation induces cell death in MAPKi-resistant melanoma cells.

Mikheil DM, Prabhakar K, Arshad A, Rodriguez CI, Newton MA, Setaluri V
Pigment cell & melanoma research 2019 Jul;32(4):528-539

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Complement C3 activation regulates the production of tRNA-derived fragments Gly-tRFs and promotes alcohol-induced liver injury and steatosis.

Zhong F, Hu Z, Jiang K, Lei B, Wu Z, Yuan G, Luo H, Dong C, Tang B, Zheng C, Yang S, Zeng Y, Guo Z, Yu S, Su H, Zhang G, Qiu X, Tomlinson S, He S
Cell research 2019 Jul;29(7):548-561

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CtIP promotes G2/M arrest in etoposide-treated HCT116 cells in a p53-independent manner.

Chen H, Shan J, Chen D, Wang R, Qi W, Wang H, Ke Y, Liu W, Zeng X
Journal of cellular physiology 2019 Jul;234(7):11871-11881

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DAAM1-mediated migration and invasion of ovarian cancer cells are suppressed by miR-208a-5p.

Mei J, Huang Y, Hao L, Liu Y, Yan T, Qiu T, Xu R, Xu B, Xiao Z, Jiang X, Hu K, Zhu Y
Pathology, research and practice 2019 Jul;215(7):152452

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CDK1 and CDK2 regulate NICD1 turnover and the periodicity of the segmentation clock.

Carrieri FA, Murray PJ, Ditsova D, Ferris MA, Davies P, Dale JK
EMBO reports 2019 Jul;20(7):e46436

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Harnessing the anti-cancer natural product nimbolide for targeted protein degradation.

Spradlin JN, Hu X, Ward CC, Brittain SM, Jones MD, Ou L, To M, Proudfoot A, Ornelas E, Woldegiorgis M, Olzmann JA, Bussiere DE, Thomas JR, Tallarico JA, McKenna JM, Schirle M, Maimone TJ, Nomura DK
Nature chemical biology 2019 Jul;15(7):747-755

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Observation of novel COX20 mutations related to autosomal recessive axonal neuropathy and static encephalopathy.

Xu H, Ji T, Lian Y, Wang S, Chen X, Li S, Yin Y, Dong X
Human genetics 2019 Jul;138(7):749-756

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Low-dose PCB126 compromises circadian rhythms associated with disordered glucose and lipid metabolism in mice.

Shen X, Chen Y, Zhang J, Yan X, Liu W, Guo Y, Shan Q, Liu S
Environment international 2019 Jul;128:146-157

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UCP2 alleviates tubular epithelial cell apoptosis in lipopolysaccharide-induced acute kidney injury by decreasing ROS production.

Zhong X, He J, Zhang X, Li C, Tian X, Xia W, Gan H, Xia Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108914

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Roscovitine attenuates renal interstitial fibrosis in diabetic mice through the TGF-β1/p38 MAPK pathway.

Wang S, Zhou Y, Zhang Y, He X, Zhao X, Zhao H, Liu W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108895

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Naringenin ameliorates insulin resistance by modulating endoplasmic reticulum stress in hepatitis C virus-infected liver.

Jia B, Wang Y, Yu G, Cheng Y, Yang C, Cao F, He Y, Cao P, Meng X, Yu D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108848

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Regulation of CD11b by HIF-1α and the STAT3 signaling pathway contributes to the immunosuppressive function of B cells in inflammatory bowel disease.

Qian T, Hong J, Wang L, Wang Z, Lu Z, Li Y, Liu R, Chu Y
Molecular immunology 2019 Jul;111:162-171

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Lysine glutarylation in human sperm is associated with progressive motility.

Cheng YM, Hu XN, Peng Z, Pan TT, Wang F, Chen HY, Chen WQ, Zhang Y, Zeng XH, Luo T
Human reproduction (Oxford, England) 2019 Jul 8;34(7):1186-1194

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Inhibition of nucleotide synthesis promotes replicative senescence of human mammary epithelial cells.

Delfarah A, Parrish S, Junge JA, Yang J, Seo F, Li S, Mac J, Wang P, Fraser SE, Graham NA
The Journal of biological chemistry 2019 Jul 5;294(27):10564-10578

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A novel hydrogen sulfide-releasing donor, HA-ADT, suppresses the growth of human breast cancer cells through inhibiting the PI3K/AKT/mTOR and Ras/Raf/MEK/ERK signaling pathways.

Dong Q, Yang B, Han JG, Zhang MM, Liu W, Zhang X, Yu HL, Liu ZG, Zhang SH, Li T, Wu DD, Ji XY, Duan SF
Cancer letters 2019 Jul 28;455:60-72

---

Lingguizhugan decoction attenuates diet-induced obesity and hepatosteatosis via gut microbiota.

Liu MT, Huang YJ, Zhang TY, Tan LB, Lu XF, Qin J
World journal of gastroenterology 2019 Jul 21;25(27):3590-3606

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Hypoxia inducible factor 1α in vascular smooth muscle cells promotes angiotensin II-induced vascular remodeling via activation of CCL7-mediated macrophage recruitment.

Qi D, Wei M, Jiao S, Song Y, Wang X, Xie G, Taranto J, Liu Y, Duan Y, Yu B, Li H, Shah YM, Xu Q, Du J, Gonzalez FJ, Qu A
Cell death & disease 2019 Jul 18;10(8):544

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AcMNPV PKIP is associated with nucleocapsid of budded virions and involved in nucleocapsid assembly.

Lai Q, Zhu L, Xu L, Yuan M, Wu W, Yang K
Virus research 2019 Jul 15;268:27-37

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CUL7 E3 Ubiquitin Ligase Mediates the Degradation of Activation-Induced Cytidine Deaminase and Regulates the Ig Class Switch Recombination in B Lymphocytes.

Luo Y, Liu Y, Wu L, Ma X, Liu Q, Huang F, Zhang X, Zhang Y, Zhang J, Luo H, Yang Y, Lu G, Tang X, Li L, Zeng Y, Pan T, Zhang H
Journal of immunology (Baltimore, Md. : 1950) 2019 Jul 1;203(1):269-281

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Tri-ortho-cresyl phosphate (TOCP) induced ovarian failure in mice is related to the Hippo signaling pathway disruption.

Hu L, Peng T, Huang J, Su T, Luo R, Zheng Y, Zhong Z, Yu P, Nie K, Zheng L
Reproductive toxicology (Elmsford, N.Y.) 2019 Jan;83:21-27

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Autocrine secretions enhance radioresistance in an exosome‑independent manner in NSCLC cells.

Wang S, Gao P, Li N, Chen P, Wang J, He N, Ji K, Du L, Liu Q
International journal of oncology 2019 Jan;54(1):229-238

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Generation of a heterozygous p53 R249S mutant human embryonic stem cell line by TALEN-mediated genome editing.

Huo Z, Tu J, Xu A, Li Y, Wang D, Liu M, Zhou R, Zhu D, Lin Y, Gingold JA, Yen CJ, Xiao H, Zhao R
Stem cell research 2019 Jan;34:101360

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miR-132-3p boosts caveolae-mediated transcellular transport in glioma endothelial cells by targeting PTEN/PI3K/PKB/Src/Cav-1 signaling pathway.

Gu Y, Cai R, Zhang C, Xue Y, Pan Y, Wang J, Zhang Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jan;33(1):441-454

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Plant-derived alkaloid sinomenine potentiates glucocorticoid pharmacodynamics in mitogen-activated human peripheral blood mononuclear cells by regulating the translocation of glucocorticoid receptor.

Xu W, Wang X, Tu Y, Masaki H, Tanaka S, Onda K, Sugiyama K, Yamada H, Hirano T
Phytotherapy research : PTR 2019 Jan;33(1):187-196

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MMP-9 Upregulation is Attenuated by the Monoclonal TLR2 Antagonist T2.5 After Oxygen-Glucose Deprivation and Reoxygenation in Rat Brain Microvascular Endothelial Cells.

Zhu H, Dai R, Fu H, Meng Q
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2019 Jan;28(1):97-106

---

Function of BRD4 in the pathogenesis of high glucose‑induced cardiac hypertrophy.

Wang Q, Sun Y, Li T, Liu L, Zhao Y, Li L, Zhang L, Meng Y
Molecular medicine reports 2019 Jan;19(1):499-507

---

SVIP alleviates CCl(4)-induced liver fibrosis via activating autophagy and protecting hepatocytes.

Jia D, Wang YY, Wang P, Huang Y, Liang DY, Wang D, Cheng C, Zhang C, Guo L, Liang P, Wang Y, Jia Y, Li C
Cell death & disease 2019 Jan 25;10(2):71

---

LncRNA SNHG12 inhibits miR-199a to upregulate SIRT1 to attenuate cerebral ischemia/reperfusion injury through activating AMPK signaling pathway.

Yin WL, Yin WG, Huang BS, Wu LX
Neuroscience letters 2019 Jan 18;690:188-195

---

Reciprocal regulation of integrin β4 and KLF4 promotes gliomagenesis through maintaining cancer stem cell traits.

Ma B, Zhang L, Zou Y, He R, Wu Q, Han C, Zhang B
Journal of experimental & clinical cancer research : CR 2019 Jan 18;38(1):23

---

MMP13 inhibition rescues cognitive decline in Alzheimer transgenic mice via BACE1 regulation.

Zhu BL, Long Y, Luo W, Yan Z, Lai YJ, Zhao LG, Zhou WH, Wang YJ, Shen LL, Liu L, Deng XJ, Wang XF, Sun F, Chen GJ
Brain : a journal of neurology 2019 Jan 1;142(1):176-192

---

Mechanism underlying the retarded nuclear translocation of androgen receptor splice variants.

Liu Y, Wang Y, Wang F, Pan J, Xu J, Li J, Zhou C, Ding G, Wu Y, Liu X, Sheng J, Huang H
Science China. Life sciences 2019 Feb;62(2):257-267

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Sodium rutin ameliorates Alzheimer's disease-like pathology by enhancing microglial amyloid-β clearance.

Pan RY, Ma J, Kong XX, Wang XF, Li SS, Qi XL, Yan YH, Cheng J, Liu Q, Jin W, Tan CH, Yuan Z
Science advances 2019 Feb;5(2):eaau6328

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Nucleoporin 107 facilitates the nuclear export of Scn5a mRNA to regulate cardiac bioelectricity.

Guan Y, Gao X, Tang Q, Huang L, Gao S, Yu S, Huang J, Li J, Zhou D, Zhang Y, Shi D, Liang D, Liu Y, Li L, Cui Y, Xu L, Chen YH
Journal of cellular and molecular medicine 2019 Feb;23(2):1448-1457

---

Effects of Fluoride on Autophagy in Mouse Sertoli Cells.

Feng Z, Liang C, Manthari RK, Wang C, Zhang J
Biological trace element research 2019 Feb;187(2):499-505

---

CDK11(p110) plays a critical role in the tumorigenicity of esophageal squamous cell carcinoma cells and is a potential drug target.

Du Y, Yan D, Yuan Y, Xu J, Wang S, Yang Z, Cheng W, Tian X, Kan Q
Cell cycle (Georgetown, Tex.) 2019 Feb;18(4):452-466

---

Berberrubine and its analog, hydroxypropyl-berberrubine, regulate LDLR and PCSK9 expression via the ERK signal pathway to exert cholesterol-lowering effects in human hepatoma HepG2 cells.

Cao S, Xu P, Yan J, Liu H, Liu L, Cheng L, Qiu F, Kang N
Journal of cellular biochemistry 2019 Feb;120(2):1340-1349

---

Intestinal non-canonical NFκB signaling shapes the local and systemic immune response.

Ramakrishnan SK, Zhang H, Ma X, Jung I, Schwartz AJ, Triner D, Devenport SN, Das NK, Xue X, Zeng MY, Hu Y, Mortensen RM, Greenson JK, Cascalho M, Wobus CE, Colacino JA, Nunez G, Rui L, Shah YM
Nature communications 2019 Feb 8;10(1):660

---

Dietary canolol induces apoptosis in human cervical carcinoma HeLa cells through ROS-MAPK mediated mitochondrial signaling pathway: In vitro and in vivo.

Xia X, Xiang X, Huang F, Zheng M, Zhang Z, Han L
Chemico-biological interactions 2019 Feb 25;300:138-150

---

Regulation of macrophage iron homeostasis is associated with the localization of bacteria.

Gan Z, Tang X, Wang Z, Li J, Wang Z, Du H
Metallomics : integrated biometal science 2019 Feb 20;11(2):454-461

---

Kibra Modulates Learning and Memory via Binding to Dendrin.

Ji Z, Li H, Yang Z, Huang X, Ke X, Ma S, Lin Z, Lu Y, Zhang M
Cell reports 2019 Feb 19;26(8):2064-2077.e7

---

miR-33 and RIP140 participate in LPS-induced acute lung injury.

Li H, Hou H, Liu S, Feng Y, Zhong W, Hu X, Yan N
Turkish journal of medical sciences 2019 Feb 11;49(1):422-428

---

Gene expression profile-based drug screen identifies SAHA as a novel treatment for NAFLD.

Cheng Z, Wen Y, Liang B, Chen S, Liu Y, Wang Z, Cheng J, Tang X, Xin H, Deng L
Molecular omics 2019 Feb 11;15(1):50-58

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The Autographa californica Multiple Nucleopolyhedrovirus ac51 Gene Is Required for Efficient Nuclear Egress of Nucleocapsids and Is Essential for In Vivo Virulence.

Qiu J, Tang Z, Cai Y, Wu W, Yuan M, Yang K
Journal of virology 2019 Feb 1;93(3)

---

JAK2/STAT1-mediated HMGB1 translocation increases inflammation and cell death in a ventilator-induced lung injury model.

Liu Q, Xie W, Wang Y, Chen S, Han J, Wang L, Gui P, Wu Q
Laboratory investigation; a journal of technical methods and pathology 2019 Dec;99(12):1810-1821

---

LncRNA SNHG4 promotes the proliferation, migration, invasiveness, and epithelial-mesenchymal transition of lung cancer cells by regulating miR-98-5p.

Tang Y, Wu L, Zhao M, Zhao G, Mao S, Wang L, Liu S, Wang X
Biochemistry and cell biology = Biochimie et biologie cellulaire 2019 Dec;97(6):767-776

---

NO donor inhibits proliferation and induces apoptosis by targeting PI3K/AKT/mTOR and MEK/ERK pathways in hepatocellular carcinoma cells.

Liu L, Chen J, Cao M, Wang J, Wang S
Cancer chemotherapy and pharmacology 2019 Dec;84(6):1303-1314

---

Carpesium abrotanoides (L.) Root as a Potential Source of Natural Anticancer Compounds: Targeting Glucose Metabolism and PKM2/HIF-1α Axis of Breast Cancer Cells.

Chai XX, Le YF, Wang JC, Mei CX, Feng JF, Zhao H, Wang C, Lu DZ
Journal of food science 2019 Dec;84(12):3825-3832

---

Indoxyl sulfate-induced calcification of vascular smooth muscle cells via the PI3K/Akt/NF-κB signaling pathway.

He X, Jiang H, Gao F, Liang S, Wei M, Chen L
Microscopy research and technique 2019 Dec;82(12):2000-2006

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Peroxisome Proliferator-Activated Receptors (PPARs) levels in spermatozoa of normozoospermic and asthenozoospermic men.

Mousavi MS, Shahverdi A, Drevet J, Akbarinejad V, Esmaeili V, Sayahpour FA, Topraggaleh TR, Rahimizadeh P, Alizadeh A
Systems biology in reproductive medicine 2019 Dec;65(6):409-419

---

LncRNA-241 inhibits 1,2-Dichloroethane-induced hepatic apoptosis.

Zeng N, Zhang Z, Jiang H, Li R, Chang C, Wang F, Xu D, Fan Q, Wang T, Xiao Y, Chen W, Shan Z, Huang Z, Wang Q
Toxicology in vitro : an international journal published in association with BIBRA 2019 Dec;61:104650

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Lipopolysaccharide-induced DNA damage response activates nuclear factor κB signalling pathway via GATA4 in dental pulp cells.

Qiao W, Huang Y, Bian Z, Sun X, Wang X, Gao Q, Peng Y, Meng L
International endodontic journal 2019 Dec;52(12):1704-1715

---

Transcriptome sequencing of Eospalax fontanierii to determine hypoxia regulation of cardiac fibrinogen.

Xu L, Hao Z, Lin J, Zhao Q, Zhang B, Li G, He J, Li J
Molecular biology reports 2019 Dec;46(6):5671-5683

---

Dysregulated Transcription Factor TFAP2A After Peripheral Nerve Injury Modulated Schwann Cell Phenotype.

Zhang F, Gu X, Yi S, Xu H
Neurochemical research 2019 Dec;44(12):2776-2785

---

ORP4L couples IP(3) to ITPR1 in control of endoplasmic reticulum calcium release.

Cao X, Chen J, Li D, Xie P, Xu M, Lin W, Li S, Pan G, Tang Y, Xu J, Olkkonen VM, Yan D, Zhong W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Dec;33(12):13852-13865

---

Base pair editing in goat: nonsense codon introgression into FGF5 results in longer hair.

Li G, Zhou S, Li C, Cai B, Yu H, Ma B, Huang Y, Ding Y, Liu Y, Ding Q, He C, Zhou J, Wang Y, Zhou G, Li Y, Yan Y, Hua J, Petersen B, Jiang Y, Sonstegard T, Huang X, Chen Y, Wang X
The FEBS journal 2019 Dec;286(23):4675-4692

---

Rotenone protects against β-cell apoptosis and attenuates type 1 diabetes mellitus.

Wu M, Chen W, Zhang S, Huang S, Zhang A, Zhang Y, Jia Z
Apoptosis : an international journal on programmed cell death 2019 Dec;24(11-12):879-891

---

S100A9 regulates porcine reproductive and respiratory syndrome virus replication by interacting with the viral nucleocapsid protein.

Song Z, Bai J, Liu X, Nauwynck H, Wu J, Liu X, Jiang P
Veterinary microbiology 2019 Dec;239:108498

---

Tandem repeat sequence of duck circovirus serves as downstream sequence element to regulate viral gene expression.

Wu ZC, Xia XJ, Li HR, Jiang SJ, Ma ZY, Wang X
Veterinary microbiology 2019 Dec;239:108496

---

MicroRNA-181b-5p modulates tumor necrosis factor-α-induced inflammatory responses by targeting interleukin-6 in cementoblasts.

Wang X, Sun H, Liu H, Ma L, Jiang C, Liao H, Xu S, Xiang J, Cao Z
Journal of cellular physiology 2019 Dec;234(12):22719-22730

---

Role of nuclear factor-κB pathway in the transition of mouse secondary follicles to antral follicles.

Xu JJ, Wang G, Luo X, Wang LJ, Bao Y, Yang X
Journal of cellular physiology 2019 Dec;234(12):22565-22580

---

miR-451a inhibits cancer growth, epithelial-mesenchymal transition and induces apoptosis in papillary thyroid cancer by targeting PSMB8.

Fan X, Zhao Y
Journal of cellular and molecular medicine 2019 Dec;23(12):8067-8075

---

Punicalagin Reversed the Hepatic Injury of Tetrachloromethane by Antioxidation and Enhancement of Autophagy.

Luo J, Long Y, Ren G, Zhang Y, Chen J, Huang R, Yang L
Journal of medicinal food 2019 Dec;22(12):1271-1279

---

Hypoxia enhances IL-10-producing B cell generation through upregulating high-mobility group B1 on tumor cell-released autophagosomes.

Zhang Y, Pan N, Sheng Y, Zhou M, Wen Z, Chen Y, Huang F, Wang LX
Immunology letters 2019 Dec;216:36-42

---

Novel sphingomyelin biomarkers for brain glioma and associated regulation research on the PI3K/Akt signaling pathway.

Zhai XH, Xiao J, Yu JK, Sun H, Zheng S
Oncology letters 2019 Dec;18(6):6207-6213

---

Catalpol alleviates adriamycin-induced nephropathy by activating the SIRT1 signalling pathway in vivo and in vitro.

Zhang J, Bi R, Meng Q, Wang C, Huo X, Liu Z, Wang C, Sun P, Sun H, Ma X, Wu J, Liu K
British journal of pharmacology 2019 Dec;176(23):4558-4573

---

HDAC11 restricts HBV replication through epigenetic repression of cccDNA transcription.

Yuan Y, Zhao K, Yao Y, Liu C, Chen Y, Li J, Wang Y, Pei R, Chen J, Hu X, Zhou Y, Wu C, Chen X
Antiviral research 2019 Dec;172:104619

---

BECN1 promotes the migration of NSCLC cells through regulating the ubiquitination of Vimentin.

Cheng Z, Xin H, Han T
Cell adhesion & migration 2019 Dec;13(1):249-259

---

Xiaoerfupi alleviates the symptoms of functional dyspepsia by regulating the HTR3A and c-FOS.

Ji E, Wang T, Guo F, Zhang Y, Tang C, Tang D, Wei J, Yang H, Xian M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109442

---

Pleiotropic Effects of Epithelial Mesenchymal Crosstalk on Head and Neck Cancer: EMT and beyond.

Steinbichler TB, Savic D, Dejaco D, Romani A, Kofler B, Skvortsova II, Riechelmann H, Dudas J
Cancer microenvironment : official journal of the International Cancer Microenvironment Society 2019 Dec;12(2-3):67-76

---

Endocytic degradation of ErbB2 mediates the effectiveness of neratinib in the suppression of ErbB2-positive ovarian cancer.

Wang S, Zhang J, Wang T, Ren F, Liu X, Lu Y, Xu L, Zhang Y, Wang D, Xu L, Wu Y, Liu F, Li Q, Zaky MY, Liu S, Dong W, Liu F, Zou K, Zhang Y
The international journal of biochemistry & cell biology 2019 Dec;117:105640

---

Curcumin inhibits LPS-induced neuroinflammation by promoting microglial M2 polarization via TREM2/ TLR4/ NF-κB pathways in BV2 cells.

Zhang J, Zheng Y, Luo Y, Du Y, Zhang X, Fu J
Molecular immunology 2019 Dec;116:29-37

---

Critical roles of NLRP3 inflammasome in IL-1β secretion induced by Corynebacterium pseudotuberculosis in vitro.

Zhou Z, Li H, Tian S, Yi W, Zhou Y, Yang H, Li X, Wu B, Li X, Wu J, Wang Z, Hu S, Fang R
Molecular immunology 2019 Dec;116:11-17

---

Activating macrophages for enhanced osteogenic and bactericidal performance by Cu ion release from micro/nano-topographical coating on a titanium substrate.

Huang Q, Ouyang Z, Tan Y, Wu H, Liu Y
Acta biomaterialia 2019 Dec;100:415-426

---

Oral Administration of Succinoglycan Riclin Improves Diet-Induced Hypercholesterolemia in Mice.

Yang Y, Sun Q, Xu X, Yang X, Gao Y, Sun X, Zhao Y, Ding Z, Ge W, Cheng R, Zhang J
Journal of agricultural and food chemistry 2019 Dec 4;67(48):13307-13317

---

Yes-associated protein regulates podocyte cell cycle re-entry and dedifferentiation in adriamycin-induced nephropathy.

Xie K, Xu C, Zhang M, Wang M, Min L, Qian C, Wang Q, Ni Z, Mou S, Dai H, Pang H, Gu L
Cell death & disease 2019 Dec 4;10(12):915

---

Sal B Alleviates Myocardial Ischemic Injury by Inhibiting TLR4 and the Priming Phase of NLRP3 Inflammasome.

Hu Y, Li Q, Pan Y, Xu L
Molecules (Basel, Switzerland) 2019 Dec 3;24(23)

---

Hydrogen sulfide attenuates mitochondrial dysfunction-induced cellular senescence and apoptosis in alveolar epithelial cells by upregulating sirtuin 1.

Guan R, Cai Z, Wang J, Ding M, Li Z, Xu J, Li Y, Li J, Yao H, Liu W, Qian J, Deng B, Tang C, Sun D, Lu W
Aging 2019 Dec 23;11(24):11844-11864

---

Beneficial Effects of Ticagrelor on Oxidized Low-Density Lipoprotein (ox-LDL)-Induced Apoptosis in Human Umbilical Vein Endothelial Cells.

Kang M, Shao S, Zhang Y, Liang X, Zhang K, Li G
Medical science monitor : international medical journal of experimental and clinical research 2019 Dec 21;25:9811-9819

---

Mechanosensing during directed cell migration requires dynamic actin polymerization at focal adhesions.

Puleo JI, Parker SS, Roman MR, Watson AW, Eliato KR, Peng L, Saboda K, Roe DJ, Ros R, Gertler FB, Mouneimne G
The Journal of cell biology 2019 Dec 2;218(12):4215-4235

---

RASAL1 induces to downregulate the SCD1, leading to suppression of cell proliferation in colon cancer via LXRα/SREBP1c pathway.

Wang G, Li Z, Li X, Zhang C, Peng L
Biological research 2019 Dec 17;52(1):60

---

Stasimon Contributes to the Loss of Sensory Synapses and Motor Neuron Death in a Mouse Model of Spinal Muscular Atrophy.

Simon CM, Van Alstyne M, Lotti F, Bianchetti E, Tisdale S, Watterson DM, Mentis GZ, Pellizzoni L
Cell reports 2019 Dec 17;29(12):3885-3901.e5

---

Gdf11 gene transfer prevents high fat diet-induced obesity and improves metabolic homeostasis in obese and STZ-induced diabetic mice.

Lu B, Zhong J, Pan J, Yuan X, Ren M, Jiang L, Yang Y, Zhang G, Liu D, Zhang C
Journal of translational medicine 2019 Dec 17;17(1):422

---

Integration of transcriptomics and network analysis deciphers the mechanisms of baicalein in improving learning and memory impairment in senescence-accelerated mouse prone 8 (SAMP8).

Li J, Zhou Y, Du G, Qin X, Gao L
European journal of pharmacology 2019 Dec 15;865:172789

---

Rafoxanide promotes apoptosis and autophagy of gastric cancer cells by suppressing PI3K /Akt/mTOR pathway.

Liu JZ, Hu YL, Feng Y, Guo YB, Liu YF, Yang JL, Mao QS, Xue WJ
Experimental cell research 2019 Dec 15;385(2):111691

---

PI3K/Akt inhibitor partly decreases TNF-α-induced activation of fibroblast-like synoviocytes in osteoarthritis.

Liu S, Cao C, Zhang Y, Liu G, Ren W, Ye Y, Sun T
Journal of orthopaedic surgery and research 2019 Dec 11;14(1):425

---

Aptamer-Based Erythrocyte-Derived Mimic Vesicles Loaded with siRNA and Doxorubicin for the Targeted Treatment of Multidrug-Resistant Tumors.

Wang T, Luo Y, Lv H, Wang J, Zhang Y, Pei R
ACS applied materials & interfaces 2019 Dec 11;11(49):45455-45466

---

7-O-geranylquercetin contributes to reverse P-gp-mediated adriamycin resistance in breast cancer.

Zhang E, Liu J, Shi L, Guo X, Liang Z, Zuo J, Xu H, Wang H, Shu X, Huang S, Zhang S, Kang X, Zhen Y
Life sciences 2019 Dec 1;238:116938

---

Fe(3)O(4)@OA@Poloxamer nanoparticles lower triglyceride in hepatocytes through liposuction effect and nano-enzyme effect.

Sun Y, Shi F, Niu Y, Zhang Y, Xiong F
Colloids and surfaces. B, Biointerfaces 2019 Dec 1;184:110528

---

Abnormal expression of Pappa2 gene may indirectly affect mouse hip development through the IGF signaling pathway.

Chen Y, Li L, Wang E, Zhang L, Zhao Q
Endocrine 2019 Aug;65(2):440-450

---

MIF/CD74 axis participates in inflammatory activation of Schwann cells following sciatic nerve injury.

Song H, Zhu Z, Zhou Y, Du N, Song T, Liang H, Chen X, Wang Y, Wang Y, Hu Y
Journal of molecular histology 2019 Aug;50(4):355-367

---

In Vitro Infectious Risk Assessment of Heliothis virescens ascovirus 3j (HvAV-3j) toward Non-target Vertebrate Cells.

Yu H, Ou-Yang YY, Li N, Nakai M, Huang GH
Virologica Sinica 2019 Aug;34(4):423-433

---

PLZF regulates apoptosis of leukemia cells by regulating AKT/Foxo3a pathway.

Li JX, Zhang ZF, Wang XB, Yang EQ, Dong L, Meng J
European review for medical and pharmacological sciences 2019 Aug;23(15):6411-6418

---

The effects of fluorene-9-bisphenol on female zebrafish (Danio rerio) reproductive and exploratory behaviors.

Mi P, Zhang QP, Zhang SH, Wang C, Zhang SZ, Fang YC, Gao JZ, Feng DF, Chen DY, Feng XZ
Chemosphere 2019 Aug;228:398-411

---

17β‑Estradiol protects against interleukin‑1β‑induced apoptosis in rat nucleus pulposus cells via the mTOR/caspase‑3 pathway.

Guo HT, Yang SD, Zhang F, Liu S, Yang DL, Ma L, Wang H, Ding WY
Molecular medicine reports 2019 Aug;20(2):1523-1530

---

Proteomic Analysis Reveals that Odoroside A Triggers G2/M Arrest and Apoptosis in Colorectal Carcinoma Through ROS-p53 Pathway.

Chen YY, Wen SY, Deng CM, Yin XF, Sun ZH, Jiang MM, He QY
Proteomics 2019 Aug;19(15):e1900092

---

Diosgenin regulates cholesterol metabolism in hypercholesterolemic rats by inhibiting NPC1L1 and enhancing ABCG5 and ABCG8.

Li R, Liu Y, Shi J, Yu Y, Lu H, Yu L, Liu Y, Zhang F
Biochimica et biophysica acta. Molecular and cell biology of lipids 2019 Aug;1864(8):1124-1133

---

HSF1 phosphorylation by cyclosporin A confers hyperthermia sensitivity through suppression of HSP expression.

Shao J, Han B, Cao P, Zhang B, Liu M, Li D, Zhou N, Hao Q, Duan X, Chang Y, Nakai A, Fan Y, Tan K
Biochimica et biophysica acta. Gene regulatory mechanisms 2019 Aug;1862(8):846-857

---

Sesterterpene MHO7 suppresses breast cancer cells as a novel estrogen receptor degrader.

Zhao Y, Zhao C, Lu J, Wu J, Li C, Hu Z, Tian W, Yang L, Xiang J, Zhou H, Deng Z, Huang J, Hong K
Pharmacological research 2019 Aug;146:104294

---

Proteomic analysis of murine bone marrow derived dendritic cells in response to peste des petits ruminants virus.

Li L, Wu J, Cao X, Zhou J, Yin S, Yang S, Feng Q, Du P, Liu Y, Shang Y, Liu Y, Liu X
Research in veterinary science 2019 Aug;125:195-204

---

Involvement of microRNA-23b-5p in the promotion of cardiac hypertrophy and dysfunction via the HMGB2 signaling pathway.

Boureima Oumarou D, Ji H, Xu J, Li S, Ruan W, Xiao F, Yu F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Aug;116:108977

---

Interleukin-1 receptor associated kinase (IRAK)-M -mediated type 2 microglia polarization ameliorates the severity of experimental autoimmune encephalomyelitis (EAE).

Liu B, Gu Y, Pei S, Peng Y, Chen J, Pham LV, Shen HY, Zhang J, Wang H
Journal of autoimmunity 2019 Aug;102:77-88

---

USP49 potently stabilizes APOBEC3G protein by removing ubiquitin and inhibits HIV-1 replication.

Pan T, Song Z, Wu L, Liu G, Ma X, Peng Z, Zhou M, Liang L, Liu B, Liu J, Zhang J, Zhang X, Huang R, Zhao J, Li Y, Ling X, Luo Y, Tang X, Cai W, Deng K, Li L, Zhang H
eLife 2019 Aug 9;8

---

Bone marrow-derived mesenchymal stromal cells promote resistance to tyrosine kinase inhibitors in chronic myeloid leukemia via the IL-7/JAK1/STAT5 pathway.

Zhang X, Tu H, Yang Y, Jiang X, Hu X, Luo Q, Li J
The Journal of biological chemistry 2019 Aug 9;294(32):12167-12179

---

ANLN-induced EZH2 upregulation promotes pancreatic cancer progression by mediating miR-218-5p/LASP1 signaling axis.

Wang A, Dai H, Gong Y, Zhang C, Shu J, Luo Y, Jiang Y, Liu W, Bie P
Journal of experimental & clinical cancer research : CR 2019 Aug 8;38(1):347

---

Jingfukang induces anti-cancer activity through oxidative stress-mediated DNA damage in circulating human lung cancer cells.

Que Z, Zhou Z, Luo B, Dong C, Jiang Y, Li H, Tian J
BMC complementary and alternative medicine 2019 Aug 7;19(1):204

---

Platelet-Membrane-Camouflaged Black Phosphorus Quantum Dots Enhance Anticancer Effect Mediated by Apoptosis and Autophagy.

Shang Y, Wang Q, Wu B, Zhao Q, Li J, Huang X, Chen W, Gui R
ACS applied materials & interfaces 2019 Aug 7;11(31):28254-28266

---

Large-conductance calcium-activated potassium channels mediate lipopolysaccharide-induced activation of murine microglia.

Yang X, Wang G, Cao T, Zhang L, Ma Y, Jiang S, Teng X, Sun X
The Journal of biological chemistry 2019 Aug 30;294(35):12921-12932

---

ORMDL3 knockdown in the lungs alleviates airway inflammation and airway remodeling in asthmatic mice via JNK1/2-MMP-9 pathway.

Wang H, Liu Y, Shi J, Cheng Z
Biochemical and biophysical research communications 2019 Aug 27;516(3):739-746

---

Glial response in early stages of traumatic brain injury.

Zhao J, Wang B, Huang T, Guo X, Yang Z, Song J, Zhang M
Neuroscience letters 2019 Aug 24;708:134335

---

Divergent engagements between adeno-associated viruses with their cellular receptor AAVR.

Zhang R, Xu G, Cao L, Sun Z, He Y, Cui M, Sun Y, Li S, Li H, Qin L, Hu M, Yuan Z, Rao Z, Ding W, Rao Z, Lou Z
Nature communications 2019 Aug 21;10(1):3760

---

BMAL1 Disrupted Intrinsic Diurnal Oscillation in Rat Cerebrovascular Contractility of Simulated Microgravity Rats by Altering Circadian Regulation of miR-103/Ca(V)1.2 Signal Pathway.

Chen L, Zhang B, Yang L, Bai YG, Song JB, Ge YL, Ma HZ, Cheng JH, Ma J, Xie MJ
International journal of molecular sciences 2019 Aug 14;20(16)

---

Induction of Fibroblast Senescence During Mouse Corneal Wound Healing.

Wang X, Qu M, Li J, Danielson P, Yang L, Zhou Q
Investigative ophthalmology & visual science 2019 Aug 1;60(10):3669-3679

---

Temporal induction of intestinal epithelial hypoxia-inducible factor-2α is sufficient to drive colitis.

Solanki S, Devenport SN, Ramakrishnan SK, Shah YM
American journal of physiology. Gastrointestinal and liver physiology 2019 Aug 1;317(2):G98-G107

---

The fucoidan A3 from the seaweed Ascophyllum nodosum enhances RCT-related genes expression in hyperlipidemic C57BL/6J mice.

Yang Z, Yin J, Wang Y, Wang J, Xia B, Li T, Yang X, Hu S, Ji C, Guo S
International journal of biological macromolecules 2019 Aug 1;134:759-769

---

The fucoidan from the brown seaweed Ascophyllum nodosum ameliorates atherosclerosis in apolipoprotein E-deficient mice.

Yin J, Wang J, Li F, Yang Z, Yang X, Sun W, Xia B, Li T, Song W, Guo S
Food & function 2019 Aug 1;10(8):5124-5139

---

The status of ω-3 PUFAs influence chronic unpredicted mild stress-induced metabolic side effects in rats through INSIG/SREBP pathway.

Tang M, Floyd S, Cai H, Zhang M, Yang R, Dang R
Food & function 2019 Aug 1;10(8):4649-4660

---

LncRNA THOR increases osteosarcoma cell stemness and migration by enhancing SOX9 mRNA stability.

Wu H, He Y, Chen H, Liu Y, Wei B, Chen G, Lin H, Lin H
FEBS open bio 2019 Apr;9(4):781-790

---

SRT1720 retards renal fibrosis via inhibition of HIF1A/GLUT1 in diabetic nephropathy.

Han W, Wang C, Yang Z, Mu L, Wu M, Chen N, Du C, Duan H, Shi Y
The Journal of endocrinology 2019 Apr;241(1):85-98

---

Nerve growth factor prevents arsenic-induced toxicity in PC12 cells through the AKT/GSK-3β/NFAT pathway.

Tan Z, Kang T, Zhang X, Tong Y, Chen S
Journal of cellular physiology 2019 Apr;234(4):4726-4738

---

NLRP3 inflammasome plays an important role in caspase-1 activation and IL-1β secretion in macrophages infected with Pasteurella multocida.

Fang R, Du H, Lei G, Liu Y, Feng S, Ye C, Li N, Peng Y
Veterinary microbiology 2019 Apr;231:207-213

---

Curcumin exerts cytotoxicity dependent on reactive oxygen species accumulation in non-small-cell lung cancer cells.

Wang C, Song X, Shang M, Zou W, Zhang M, Wei H, Shao H
Future oncology (London, England) 2019 Apr;15(11):1243-1253

---

Downregulation of RGMA by HIF-1A/miR-210-3p axis promotes cell proliferation in oral squamous cell carcinoma.

Lu Y, Li Y, Wang Z, Xie S, Wang Q, Lei X, Ruan Y, Li J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108608

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Aspirin ameliorates lung cancer by targeting the miR-98/WNT1 axis.

Gan H, Lin L, Hu N, Yang Y, Gao Y, Pei Y, Chen K, Sun B
Thoracic cancer 2019 Apr;10(4):744-750

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Human cells are permissive for the productive infection of porcine circovirus type 2 in vitro.

Liu X, Ouyang T, Ouyang H, Liu X, Niu G, Huo W, Yin W, Pang D, Ren L
Scientific reports 2019 Apr 4;9(1):5638

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LncRNA SNHG20 predicts a poor prognosis and promotes cell progression in epithelial ovarian cancer.

Wang D, Dai J, Hou S, Qian Y
Bioscience reports 2019 Apr 30;39(4)

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UBE2C functions as a potential oncogene by enhancing cell proliferation, migration, invasion, and drug resistance in hepatocellular carcinoma cells.

Xiong Y, Lu J, Fang Q, Lu Y, Xie C, Wu H, Yin Z
Bioscience reports 2019 Apr 30;39(4)

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Zearalenone Induces Estrogen-Receptor-Independent Neutrophil Extracellular Trap Release in Vitro.

Wang JJ, Wei ZK, Han Z, Liu ZY, Zhu XY, Li XW, Wang K, Yang ZT
Journal of agricultural and food chemistry 2019 Apr 24;67(16):4588-4594

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Excessive miR-25-3p maturation via N(6)-methyladenosine stimulated by cigarette smoke promotes pancreatic cancer progression.

Zhang J, Bai R, Li M, Ye H, Wu C, Wang C, Li S, Tan L, Mai D, Li G, Pan L, Zheng Y, Su J, Ye Y, Fu Z, Zheng S, Zuo Z, Liu Z, Zhao Q, Che X, Xie D, Jia W, Zeng MS, Tan W, Chen R, Xu RH, Zheng J, Lin D
Nature communications 2019 Apr 23;10(1):1858

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Icariin attenuates neuroinflammation and exerts dopamine neuroprotection via an Nrf2-dependent manner.

Zhang B, Wang G, He J, Yang Q, Li D, Li J, Zhang F
Journal of neuroinflammation 2019 Apr 22;16(1):92

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Ntrk1 Promotes Resistance to PD-1 Checkpoint Blockade in Mesenchymal Kras/p53 Mutant Lung Cancer.

Konen JM, Rodriguez BL, Fradette JJ, Gibson L, Davis D, Minelli R, Peoples MD, Kovacs J, Carugo A, Bristow C, Heffernan T, Gibbons DL
Cancers 2019 Apr 2;11(4)

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Macrophage migration inhibitory factor facilitates prostaglandin E(2) production of astrocytes to tune inflammatory milieu following spinal cord injury.

Zhang Y, Zhou Y, Chen S, Hu Y, Zhu Z, Wang Y, Du N, Song T, Yang Y, Guo A, Wang Y
Journal of neuroinflammation 2019 Apr 13;16(1):85

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MicroRNA-106b Regulates Milk Fat Metabolism via ATP Binding Cassette Subfamily A Member 1 ( ABCA1) in Bovine Mammary Epithelial Cells.

Chen Z, Chu S, Wang X, Fan Y, Zhan T, Arbab AAI, Li M, Zhang H, Mao Y, Loor JJ, Yang Z
Journal of agricultural and food chemistry 2019 Apr 10;67(14):3981-3990

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Immunomodulatory effects of an acidic polysaccharide fraction from herbal Gynostemma pentaphyllum tea in RAW264.7 cells.

Ren D, Zhao Y, Zheng Q, Alim A, Yang X
Food & function 2019 Apr 1;10(4):2186-2197

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Exosomal ephrinA2 derived from serum as a potential biomarker for prostate cancer.

Li S, Zhao Y, Chen W, Yin L, Zhu J, Zhang H, Cai C, Li P, Huang L, Ma P
Journal of Cancer 2018;9(15):2659-2665

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AMPH-1 is critical for breast cancer progression.

Chen Y, Liu J, Li L, Xia H, Lin Z, Zhong T
Journal of Cancer 2018;9(12):2175-2182

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The Protective Effect of Astaxanthin on Cognitive Function via Inhibition of Oxidative Stress and Inflammation in the Brains of Chronic T2DM Rats.

Feng Y, Chu A, Luo Q, Wu M, Shi X, Chen Y
Frontiers in pharmacology 2018;9:748

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Maternal Protein Restriction Induces Alterations in Hepatic Unfolded Protein Response-Related Molecules in Adult Rat Offspring.

Liu X, Wang J, Gao L, Jiao Y, Liu C
Frontiers in endocrinology 2018;9:676

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β-TrCP Restricts Lipopolysaccharide (LPS)-Induced Activation of TRAF6-IKK Pathway Upstream of IκBα Signaling.

Liu J, Yuan Y, Xu J, Xiao K, Xu Y, Guo T, Zhang L, Wang J, Zheng H
Frontiers in immunology 2018;9:2930

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The Host Restriction Factor Interferon-Inducible Transmembrane Protein 3 Inhibits Vaccinia Virus Infection.

Li C, Du S, Tian M, Wang Y, Bai J, Tan P, Liu W, Yin R, Wang M, Jiang Y, Li Y, Zhu N, Zhu Y, Li T, Wu S, Jin N, He F
Frontiers in immunology 2018;9:228

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Protective Effect of Extract of Bletilla Striata on Isoflurane Induced Neuronal Injury By Altering PI3K/Akt Pathway.

Zhao G, Li K, Chen J, Li L
Translational neuroscience 2018;9:183-189

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Magnolol Alleviates Inflammatory Responses and Lipid Accumulation by AMP-Activated Protein Kinase-Dependent Peroxisome Proliferator-Activated Receptor α Activation.

Tian Y, Feng H, Han L, Wu L, Lv H, Shen B, Li Z, Zhang Q, Liu G
Frontiers in immunology 2018;9:147

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Geniposide and Chlorogenic Acid Combination Ameliorates Non-alcoholic Steatohepatitis Involving the Protection on the Gut Barrier Function in Mouse Induced by High-Fat Diet.

Peng JH, Leng J, Tian HJ, Yang T, Fang Y, Feng Q, Zhao Y, Hu YY
Frontiers in pharmacology 2018;9:1399

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Oncolytic Newcastle disease virus induces autophagy-dependent immunogenic cell death in lung cancer cells.

Ye T, Jiang K, Wei L, Barr MP, Xu Q, Zhang G, Ding C, Meng S, Piao H
American journal of cancer research 2018;8(8):1514-1527

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Add-On therapy with Chinese herb medicine Bo-Er-Ning capsule (BENC) improves outcomes of gastric cancer patients: a randomized clinical trial followed with bioinformatics-assisted mechanism study.

Pan B, Zang J, He J, Wang Z, Liu L
American journal of cancer research 2018;8(6):1090-1105

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Liposomal Curcumin Targeting Endometrial Cancer Through the NF-κB Pathway.

Xu H, Gong Z, Zhou S, Yang S, Wang D, Chen X, Wu J, Liu L, Zhong S, Zhao J, Tang J
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(2):569-582

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Placental growth factor promotes epithelial-mesenchymal transition-like changes in ARPE-19 cells under hypoxia.

Zhang Y, Zhao L, Wang L, Yang X, Zhou A, Wang J
Molecular vision 2018;24:340-352

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Dorsal Root Ganglion Maintains Stemness of Bone Marrow Mesenchymal Stem Cells by Enhancing Autophagy through the AMPK/mTOR Pathway in a Coculture System.

Zhang S, Li J, Jiang H, Gao Y, Cheng P, Cao T, Li D, Wang J, Song Y, Liu B, Wu H, Wang C, Yang L, Pei G
Stem cells international 2018;2018:8478953

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Glucagon-Like Peptide-1 Mediates the Protective Effect of the Dipeptidyl Peptidase IV Inhibitor on Renal Fibrosis via Reducing the Phenotypic Conversion of Renal Microvascular Cells in Monocrotaline-Treated Rats.

Xu J, Wang J, Cheng Y, Li X, He M, Zhu J, Han H, Wei G, Kong H, Xie W, Wang H, Zuo X
BioMed research international 2018;2018:1864107

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Oxidative stress and NF-κB signaling are involved in LPS induced pulmonary dysplasia in chick embryos.

Long Y, Wang G, Li K, Zhang Z, Zhang P, Zhang J, Zhang X, Bao Y, Yang X, Wang P
Cell cycle (Georgetown, Tex.) 2018;17(14):1757-1771

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Foot-and-mouth disease virus capsid protein VP2 activates the cellular EIF2S1-ATF4 pathway and induces autophagy via HSPB1.

Sun P, Zhang S, Qin X, Chang X, Cui X, Li H, Zhang S, Gao H, Wang P, Zhang Z, Luo J, Li Z
Autophagy 2018;14(2):336-346

---

TRIM59 regulates autophagy through modulating both the transcription and the ubiquitination of BECN1.

Han T, Guo M, Gan M, Yu B, Tian X, Wang JB
Autophagy 2018;14(12):2035-2048

---

Linagliptin unmasks specific antioxidant pathways protective against albuminuria and kidney hypertrophy in a mouse model of diabetes.

Spencer NY, Yang Z, Sullivan JC, Klein T, Stanton RC
PloS one 2018;13(7):e0200249

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Dysregulation of Neuregulin-1/ErbB signaling in the hippocampus of rats after administration of doxorubicin.

Liao D, Guo Y, Xiang D, Dang R, Xu P, Cai H, Cao L, Jiang P
Drug design, development and therapy 2018;12:231-239

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Involvement of microRNA-146a in diabetic peripheral neuropathy through the regulation of inflammation.

Feng Y, Chen L, Luo Q, Wu M, Chen Y, Shi X
Drug design, development and therapy 2018;12:171-177

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Expression and significance of the Hedgehog signal transduction pathway in oxygen-induced retinal neovascularization in mice.

Liu M, Chen X, Liu H, Di Y
Drug design, development and therapy 2018;12:1337-1346

---

SEC24A stimulates oncogenicity of human gastric cancer cells.

Lu M, Wang W, Zhang S, Li Y
International journal of clinical and experimental pathology 2018;11(8):4044-4051

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miR-222-3p promotes osteosarcoma cell migration and invasion through targeting TIMP3.

Guo J, Liu Q, Li Z, Guo H, Bai C, Wang F
OncoTargets and therapy 2018;11:8643-8653

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Protective Effect of Hydrogen on Sodium Iodate-Induced Age-Related Macular Degeneration in Mice.

Liu Y, Li R, Xie J, Hu J, Huang X, Ren F, Li L
Frontiers in aging neuroscience 2018;10:389

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Dl-3-n-Butylphthalide improves lipopolysaccharide-induced depressive-like behavior in rats: involvement of Nrf2 and NF-κB pathways.

Yang M, Dang R, Xu P, Guo Y, Han W, Liao D, Jiang P
Psychopharmacology 2018 Sep;235(9):2573-2585

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miR-34b-5p inhibition attenuates lung inflammation and apoptosis in an LPS-induced acute lung injury mouse model by targeting progranulin.

Xie W, Lu Q, Wang K, Lu J, Gu X, Zhu D, Liu F, Guo Z
Journal of cellular physiology 2018 Sep;233(9):6615-6631

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Amyotrophic lateral sclerosis (ALS) and Alzheimer's disease (AD) are characterised by differential activation of ER stress pathways: focus on UPR target genes.

Montibeller L, de Belleroche J
Cell stress & chaperones 2018 Sep;23(5):897-912

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Exosomal zinc transporter ZIP4 promotes cancer growth and is a novel diagnostic biomarker for pancreatic cancer.

Jin H, Liu P, Wu Y, Meng X, Wu M, Han J, Tan X
Cancer science 2018 Sep;109(9):2946-2956

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Disruption of Tmem30a results in cerebellar ataxia and degeneration of Purkinje cells.

Yang Y, Sun K, Liu W, Zhang L, Peng K, Zhang S, Li S, Yang M, Jiang Z, Lu F, Zhu X
Cell death & disease 2018 Sep 5;9(9):899

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The regulatory effects of metformin on the [SNAIL/miR-34]:[ZEB/miR-200] system in the epithelial-mesenchymal transition(EMT) for colorectal cancer(CRC).

Wang Y, Wu Z, Hu L
European journal of pharmacology 2018 Sep 5;834:45-53

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Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors.

Huang X, Yan J, Zhang M, Wang Y, Chen Y, Fu X, Wei R, Zheng XL, Liu Z, Zhang X, Yang H, Hao B, Shen YY, Su Y, Cong X, Huang M, Tan M, Ding J, Geng M
Cell 2018 Sep 20;175(1):186-199.e19

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Transcriptomic but not genomic variability confers phenotype of breast cancer stem cells.

Tong M, Deng Z, Yang M, Xu C, Zhang X, Zhang Q, Liao Y, Deng X, Lv D, Zhang X, Zhang Y, Li P, Song L, Wang B, Al-Dherasi A, Li Z, Liu Q
Cancer communications (London, England) 2018 Sep 19;38(1):56

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Cattle Encephalon Glycoside and Ignotin Reduce Early Brain Injury and Cognitive Dysfunction after Subarachnoid Hemorrhage in Rats.

Ma K, Li R, Zhao H, Qu J, Mu N, Liu X, Wang S, Yang C, Feng H, Tan L, Li F
Neuroscience 2018 Sep 15;388:181-190

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Cutting Edge: Dysregulated CARD9 Signaling in Neutrophils Drives Inflammation in a Mouse Model of Neutrophilic Dermatoses.

Tartey S, Gurung P, Samir P, Burton A, Kanneganti TD
Journal of immunology (Baltimore, Md. : 1950) 2018 Sep 15;201(6):1639-1644

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Resveratrol Suppresses Matrix Metalloproteinase-2 Activation Induced by Lipopolysaccharide in Mouse Osteoblasts via Interactions with AMP-Activated Protein Kinase and Suppressor of Cytokine Signaling 1.

Yu Y, Li X, Mi J, Qu L, Yang D, Guo J, Qiu L
Molecules (Basel, Switzerland) 2018 Sep 12;23(9)

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The apoptosis in arsenic-induced oxidative stress is associated with autophagy in the testis tissues of chicken.

Shao YZ, Zhao HJ, Wang Y, Liu JJ, Li JL, Luo LY, Xing MW
Poultry science 2018 Sep 1;97(9):3248-3257

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Dipeptidyl peptidase IV (DPP-4) inhibition alleviates pulmonary arterial remodeling in experimental pulmonary hypertension.

Xu J, Wang J, He M, Han H, Xie W, Wang H, Kong H
Laboratory investigation; a journal of technical methods and pathology 2018 Oct;98(10):1333-1346

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Bone morphogenetic protein 4 expression in the developing lumbosacral spinal cord of rat embryos with anorectal malformations.

Yang Z, Jia H, Bai Y, Wang W
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2018 Oct;69:32-38

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MicroRNA-543 functions as an osteogenesis promoter in human periodontal ligament-derived stem cells by inhibiting transducer of ERBB2, 2.

Ge Y, Li J, Hao Y, Hu Y, Chen D, Wu B, Fang F
Journal of periodontal research 2018 Oct;53(5):832-841

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Curcumol induces RIPK1/RIPK3 complex-dependent necroptosis via JNK1/2-ROS signaling in hepatic stellate cells.

Jia Y, Wang F, Guo Q, Li M, Wang L, Zhang Z, Jiang S, Jin H, Chen A, Tan S, Zhang F, Shao J, Zheng S
Redox biology 2018 Oct;19:375-387

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Quantitative Global Proteome and Lysine Succinylome Analyses Reveal the Effects of Energy Metabolism in Renal Cell Carcinoma.

Zhang N, Gao R, Yang J, Zhu Y, Zhang Z, Xu X, Wang J, Liu X, Li Z, Li Z, Gong D, Li J, Bi J, Kong C
Proteomics 2018 Oct;18(19):e1800001

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Salidroside attenuates endothelial cellular senescence via decreasing the expression of inflammatory cytokines and increasing the expression of SIRT3.

Xing SS, Li J, Chen L, Yang YF, He PL, Li J, Yang J
Mechanisms of ageing and development 2018 Oct;175:1-6

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TRIM65 supports bladder urothelial carcinoma cell aggressiveness by promoting ANXA2 ubiquitination and degradation.

Wei WS, Chen X, Guo LY, Li XD, Deng MH, Yuan GJ, He LY, Li YH, Zhang ZL, Jiang LJ, Chen RX, Ma XD, Wei S, Ma NF, Liu ZW, Luo JH, Zhou FJ, Xie D
Cancer letters 2018 Oct 28;435:10-22

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Cyclophilin J limits inflammation through the blockage of ubiquitin chain sensing.

Sheng C, Yao C, Wang Z, Chen H, Zhao Y, Xu D, Huang H, Huang W, Chen S
Nature communications 2018 Oct 22;9(1):4381

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Quercetin ameliorates podocyte injury via inhibition of oxidative stress and the TGF-β1/Smad pathway in DN rats.

Gao F, He X, Liang S, Liu S, Liu H, He Q, Chen L, Jiang H, Zhang Y
RSC advances 2018 Oct 15;8(62):35413-35421

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Apelin-13 Upregulates BDNF Against Chronic Stress-induced Depression-like Phenotypes by Ameliorating HPA Axis and Hippocampal Glucocorticoid Receptor Dysfunctions.

Dai TT, Wang B, Xiao ZY, You Y, Tian SW
Neuroscience 2018 Oct 15;390:151-159

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Reduced graphene oxide triggered epithelial-mesenchymal transition in A549 cells.

Liao Y, Wang W, Huang X, Sun Y, Tian S, Cai P
Scientific reports 2018 Oct 12;8(1):15188

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Andrographolide inhibits breast cancer through suppressing COX-2 expression and angiogenesis via inactivation of p300 signaling and VEGF pathway.

Peng Y, Wang Y, Tang N, Sun D, Lan Y, Yu Z, Zhao X, Feng L, Zhang B, Jin L, Yu F, Ma X, Lv C
Journal of experimental & clinical cancer research : CR 2018 Oct 12;37(1):248

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SUMO-1 modification of FEN1 facilitates its interaction with Rad9-Rad1-Hus1 to counteract DNA replication stress.

Xu X, Shi R, Zheng L, Guo Z, Wang L, Zhou M, Zhao Y, Tian B, Truong K, Chen Y, Shen B, Hua Y, Xu H
Journal of molecular cell biology 2018 Oct 1;10(5):460-474

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Fluoride induces apoptosis and autophagy through the IL-17 signaling pathway in mice hepatocytes.

Zhao Y, Li Y, Wang J, Manthari RK, Wang J
Archives of toxicology 2018 Nov;92(11):3277-3289

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Atorvastatin Pretreatment Attenuates Ischemic Brain Edema by Suppressing Aquaporin 4.

Cheng ZJ, Dai TM, Shen YY, He JL, Li J, Tu JL
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2018 Nov;27(11):3247-3255

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Oncogenic activation of PI3K induces progenitor cell differentiation to suppress epidermal growth.

Ying Z, Sandoval M, Beronja S
Nature cell biology 2018 Nov;20(11):1256-1266

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(2R,3R)Dihydromyricetin inhibits osteoclastogenesis and bone loss through scavenging LPS-induced oxidative stress and NF-κB and MAPKs pathways activating.

Zhang X, Li X, Fang J, Hou X, Fang H, Guo F, Li F, Chen A, Huang S
Journal of cellular biochemistry 2018 Nov;119(11):8981-8995

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NR2B-Tyr phosphorylation regulates synaptic plasticity in central sensitization in a chronic migraine rat model.

Wang XY, Zhou HR, Wang S, Liu CY, Qin GC, Fu QQ, Zhou JY, Chen LX
The journal of headache and pain 2018 Nov 6;19(1):102

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MicroRNA-32 Regulates Development and Progression of Hepatocellular Carcinoma by Targeting ADAMTS9 and Affects Its Prognosis.

Li S, Li T, Li X, Yao Y, Jiang X, Zhao L, Guo W
Medical science monitor basic research 2018 Nov 5;24:177-187

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Zinc finger E-box-binding homeobox 1 mediates aerobic glycolysis via suppression of sirtuin 3 in pancreatic cancer.

Xu WY, Hu QS, Qin Y, Zhang B, Liu WS, Ni QX, Xu J, Yu XJ
World journal of gastroenterology 2018 Nov 21;24(43):4893-4905

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Estrogen receptor β upregulated by lncRNA-H19 to promote cancer stem-like properties in papillary thyroid carcinoma.

Li M, Chai HF, Peng F, Meng YT, Zhang LZ, Zhang L, Zou H, Liang QL, Li MM, Mao KG, Sun DX, Tong MY, Deng ZQ, Hou ZJ, Zhao Y, Li J, Wang XC, Lv SS, Zhang QQ, Yu X, Lam EW, Liu Q, Cui XN, Xu J
Cell death & disease 2018 Nov 2;9(11):1120

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Citrus Tangeretin Improves Skeletal Muscle Mitochondrial Biogenesis via Activating the AMPK-PGC1-α Pathway In Vitro and In Vivo: A Possible Mechanism for Its Beneficial Effect on Physical Performance.

Kou G, Li Z, Wu C, Liu Y, Hu Y, Guo L, Xu X, Zhou Z
Journal of agricultural and food chemistry 2018 Nov 14;66(45):11917-11925

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Nitric oxide triggers the assembly of "type II" stress granules linked to decreased cell viability.

Aulas A, Lyons SM, Fay MM, Anderson P, Ivanov P
Cell death & disease 2018 Nov 13;9(11):1129

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Inhibitor of Bruton's tyrosine kinases, PCI-32765, decreases pro-inflammatory mediators' production in high glucose-induced macrophages.

Fan Z, Wang Y, Xu X, Wu Y
International immunopharmacology 2018 May;58:145-153

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Overexpression of collagen type V α1 chain in human breast invasive ductal carcinoma is mediated by TGF-β1.

Ren W, Zhang Y, Zhang L, Lin Q, Zhang J, Xu G
International journal of oncology 2018 May;52(5):1694-1704

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Establishment of a human embryonic stem cell line with homozygous TP53 R248W mutant by TALEN mediated gene editing.

Xu A, Zhou R, Tu J, Huo Z, Zhu D, Wang D, Gingold JA, Mata H, Rao PH, Liu M, Mohamed AMT, Kong CSL, Jewell BE, Xia W, Zhao R, Hung MC, Lee DF
Stem cell research 2018 May;29:215-219

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Induction of OTUD1 by RNA viruses potently inhibits innate immune responses by promoting degradation of the MAVS/TRAF3/TRAF6 signalosome.

Zhang L, Liu J, Qian L, Feng Q, Wang X, Yuan Y, Zuo Y, Cheng Q, Miao Y, Guo T, Zheng X, Zheng H
PLoS pathogens 2018 May;14(5):e1007067

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Systemic administration of scAAV9-IGF1 extends survival in SOD1(G93A) ALS mice via inhibiting p38 MAPK and the JNK-mediated apoptosis pathway.

Wang W, Wen D, Duan W, Yin J, Cui C, Wang Y, Li Z, Liu Y, Li C
Brain research bulletin 2018 May;139:203-210

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Exogenous leptin affects sperm parameters and impairs blood testis barrier integrity in adult male mice.

Wang X, Zhang X, Hu L, Li H
Reproductive biology and endocrinology : RB&E 2018 May 31;16(1):55

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Promotion of autophagosome-lysosome fusion via salvianolic acid A-mediated SIRT1 up-regulation ameliorates alcoholic liver disease.

Shi X, Sun R, Zhao Y, Fu R, Wang R, Zhao H, Wang Z, Tang F, Zhang N, Tian X, Yao J
RSC advances 2018 May 30;8(36):20411-20422

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IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation.

Karki R, Lee E, Place D, Samir P, Mavuluri J, Sharma BR, Balakrishnan A, Malireddi RKS, Geiger R, Zhu Q, Neale G, Kanneganti TD
Cell 2018 May 3;173(4):920-933.e13

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Effect of propolis on preserving human periodontal ligament cells and regulating pro-inflammatory cytokines.

Yuan XJ, Wang YY, Shi BQ, Zhao YM
Dental traumatology : official publication of International Association for Dental Traumatology 2018 May 27;

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Hepatoprotection of auraptene from peels of citrus fruits against thioacetamide-induced hepatic fibrosis in mice by activating farnesoid X receptor.

Gao X, Wang C, Ning C, Liu K, Wang X, Liu Z, Sun H, Ma X, Sun P, Meng Q
Food & function 2018 May 23;9(5):2684-2694

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TRIM50 suppressed hepatocarcinoma progression through directly targeting SNAIL for ubiquitous degradation.

Ma X, Ma X, Qiu Y, Zhu L, Lin Y, You Y, Ma D, Qin Z, Sun C, Zhao Y, Sun Y, Han L
Cell death & disease 2018 May 22;9(6):608

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Geniposide attenuates Aβ(25-35)-induced neurotoxicity via the TLR4/NF-κB pathway in HT22 cells.

Huang XF, Li JJ, Tao YG, Wang XQ, Zhang RL, Zhang JL, Su ZQ, Huang QH, Deng YH
RSC advances 2018 May 22;8(34):18926-18937

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Renal protective effect of Paeoniflorin by inhibition of JAK2/STAT3 signaling pathway in diabetic mice.

Li X, Wang Y, Wang K, Wu Y
Bioscience trends 2018 May 13;12(2):168-176

---

Cell Cycle Regulation by Alternative Polyadenylation of CCND1.

Wang Q, He G, Hou M, Chen L, Chen S, Xu A, Fu Y
Scientific reports 2018 May 1;8(1):6824

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Dietary α-Mangostin Provides Protective Effects against Acetaminophen-Induced Hepatotoxicity in Mice via Akt/mTOR-Mediated Inhibition of Autophagy and Apoptosis.

Yan XT, Sun YS, Ren S, Zhao LC, Liu WC, Chen C, Wang Z, Li W
International journal of molecular sciences 2018 May 1;19(5)

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ASK1/2 signaling promotes inflammation in a mouse model of neutrophilic dermatosis.

Tartey S, Gurung P, Dasari TK, Burton A, Kanneganti TD
The Journal of clinical investigation 2018 May 1;128(5):2042-2047

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Innately activated TLR4 signal in the nucleus accumbens is sustained by CRF amplification loop and regulates impulsivity.

Balan I, Warnock KT, Puche A, Gondre-Lewis MC, Aurelian L
Brain, behavior, and immunity 2018 Mar;69:139-153

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Effects of gelling bath on the physical properties of alginate gel beads and the biological characteristics of entrapped HepG2 cells.

Sun D, Liu Y, Wu H, Ren Y, Ma X, Wu H, Sun G
Biotechnology and applied biochemistry 2018 Mar;65(2):263-273

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Insulin Treatment Cannot Promote Lipogenesis in Rat Fetal Lung in Gestational Diabetes Mellitus Because of Failure to Redress the Imbalance Among SREBP-1, SCAP, and INSIG-1.

Li J, Qian G, Zhong X, Yu T
DNA and cell biology 2018 Mar;37(3):264-270

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Ubenimex, an APN inhibitor, could serve as an anti‑tumor drug in RT112 and 5637 cells by operating in an Akt‑associated manner.

Wang X, Liu Y, Liu W, Zhang Y, Guo F, Zhang L, Cui M, Liu S, Wu R
Molecular medicine reports 2018 Mar;17(3):4531-4539

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LIFR increases the release of soluble endoglin via the upregulation of MMP14 expression in preeclampsia.

Li H, Yao J, Chang X, Wu J, Duan T, Wang K
Reproduction (Cambridge, England) 2018 Mar;155(3):297-306

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7α,8α-Epoxynagilactones and their glucosides from the twigs of Podocarpus nagi: Isolation, structures, and cytotoxic activities.

Zheng YD, Bai G, Tang C, Ke CQ, Yao S, Tong LJ, Feng F, Li Y, Ding J, Xie H, Ye Y
Fitoterapia 2018 Mar;125:174-183

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Elucidation of the Molecular-Mechanisms and In Vivo Evaluation of the Anti-inflammatory Effect of Alginate-Derived Seleno-polymannuronate.

Bi D, Lai Q, Cai N, Li T, Zhang Y, Han Q, Peng Y, Xu H, Lu J, Bao W, Liu Q, Xu X
Journal of agricultural and food chemistry 2018 Mar 7;66(9):2083-2091

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Nicotine-Induced Neuroprotection against Cognitive Dysfunction after Partial Hepatectomy Involves Activation of BDNF/TrkB Signaling Pathway and Inhibition of NF-κB Signaling Pathway in Aged Rats.

Wei P, Zheng Q, Liu H, Wan T, Zhou J, Li D, Zhou H, Li J, Ji F, Tang W, Li J
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2018 Mar 6;20(4):515-522

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Correction and Republication: Effect of Di-(2-ethylhexyl) phthalate on the hypothalamus-pituitary-thyroid axis in adolescent rat.

Sun D, Zhou L, Wang S, Liu T, Zhu J, Jia Y, Xu J, Chen H, Wang Q, Xu F, Zhang Y, Ye L
Endocrine journal 2018 Mar 28;65(3):261-268

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Exosomes from C2C12 myoblasts enhance osteogenic differentiation of MC3T3-E1 pre-osteoblasts by delivering miR-27a-3p.

Xu Q, Cui Y, Luan J, Zhou X, Li H, Han J
Biochemical and biophysical research communications 2018 Mar 25;498(1):32-37

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New Drug Candidate Targeting the 4A1 Orphan Nuclear Receptor for Medullary Thyroid Cancer Therapy.

Zhang L, Liu W, Wang Q, Li Q, Wang H, Wang J, Teng T, Chen M, Ji A, Li Y
Molecules (Basel, Switzerland) 2018 Mar 2;23(3)

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Apoptosome formation upon overexpression of native and truncated Apaf-1 in cell-free and cell-based systems.

Noori AR, Hosseini ES, Nikkhah M, Hosseinkhani S
Archives of biochemistry and biophysics 2018 Mar 15;642:46-51

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Mitochondrial Dysfunctions Contribute to Hypertrophic Cardiomyopathy in Patient iPSC-Derived Cardiomyocytes with MT-RNR2 Mutation.

Li S, Pan H, Tan C, Sun Y, Song Y, Zhang X, Yang W, Wang X, Li D, Dai Y, Ma Q, Xu C, Zhu X, Kang L, Fu Y, Xu X, Shu J, Zhou N, Han F, Qin D, Huang W, Liu Z, Yan Q
Stem cell reports 2018 Mar 13;10(3):808-821

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Cell division cycle 7 is a potential therapeutic target in oral squamous cell carcinoma and is regulated by E2F1.

Jin S, Ma H, Yang W, Ju H, Wang L, Zhang Z
Journal of molecular medicine (Berlin, Germany) 2018 Jun;96(6):513-525

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IL-6 receptor blockade ameliorates diabetic nephropathy via inhibiting inflammasome in mice.

Wu R, Liu X, Yin J, Wu H, Cai X, Wang N, Qian Y, Wang F
Metabolism: clinical and experimental 2018 Jun;83:18-24

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Metformin inhibits ovarian cancer via decreasing H3K27 trimethylation.

Tang G, Guo J, Zhu Y, Huang Z, Liu T, Cai J, Yu L, Wang Z
International journal of oncology 2018 Jun;52(6):1899-1911

---

Avian leukosis virus subgroup J promotes cell proliferation and cell cycle progression through miR-221 by targeting CDKN1B.

Ren C, Yu M, Zhang Y, Fan M, Chang F, Xing L, Liu Y, Wang Y, Qi X, Liu C, Zhang Y, Cui H, Li K, Gao L, Pan Q, Wang X, Gao Y
Virology 2018 Jun;519:121-130

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PEDF improves cardiac function in rats subjected to myocardial ischemia/reperfusion injury by inhibiting ROS generation via PEDF‑R.

Zhao Q, Liu Z, Huang B, Yuan Y, Liu X, Zhang H, Qiu F, Zhang Y, Li Y, Miao H, Dong H, Zhang Z
International journal of molecular medicine 2018 Jun;41(6):3243-3252

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Effect of Banxia Xiexin decoction on Helicobacter pylori-related peptic ulcers and its possible mechanism via the TGF-β/Smad signaling pathway.

Chen S, Huang Y, Wan S, Huang Y, Liang H, Chen S
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2018 Jun;38(3):419-426

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Doxycycline attenuates chronic intermittent hypoxia-induced atrial fibrosis in rats.

Wang W, Zhang K, Li X, Ma Z, Zhang Y, Yuan M, Suo Y, Liang X, Tse G, Goudis CA, Liu T, Li G
Cardiovascular therapeutics 2018 Jun;36(3):e12321

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Cysteine-rich protein 61 regulates adipocyte differentiation from mesenchymal stem cells through mammalian target of rapamycin complex 1 and canonical Wnt signaling.

Yang Y, Qi Q, Wang Y, Shi Y, Yang W, Cen Y, Zhu E, Li X, Chen D, Wang B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Jun;32(6):3096-3107

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A comparison of CRISPR/Cas9 and siRNA-mediated ALDH2 gene silencing in human cell lines.

Wang F, Guo T, Jiang H, Li R, Wang T, Zeng N, Dong G, Zeng X, Li D, Xiao Y, Hu Q, Chen W, Xing X, Wang Q
Molecular genetics and genomics : MGG 2018 Jun;293(3):769-783

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Effects of nicotine on the metabolism and gene expression profile of Sprague‑Dawley rat primary osteoblasts.

Liang D, Wang KJ, Tang ZQ, Liu RH, Zeng F, Cheng MY, Lian QS, Wu HK
Molecular medicine reports 2018 Jun;17(6):8269-8281

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Myxovirus resistance protein A inhibits hepatitis C virus replication through JAK-STAT pathway activation.

Wang H, Xin X, Wang M, Han L, Li J, Hao Y, Zheng C, Shen C
Archives of virology 2018 Jun;163(6):1429-1438

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Berberine exerts antioxidant effects via protection of spiral ganglion cells against cytomegalovirus-induced apoptosis.

Zhuang W, Li T, Wang C, Shi X, Li Y, Zhang S, Zhao Z, Dong H, Qiao Y
Free radical biology & medicine 2018 Jun;121:127-135

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Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.

Zhang J, Tucker LD, DongYan, Lu Y, Yang L, Wu C, Li Y, Zhang Q
Neurochemistry international 2018 Jun;116:1-12

---

Enhancer of zeste homolog 2 promotes cisplatin resistance by reducing cellular platinum accumulation.

Sun S, Zhao S, Yang Q, Wang W, Cai E, Wen Y, Yu L, Wang Z, Cai J
Cancer science 2018 Jun;109(6):1853-1864

---

Acetylation of oxidized base repair-initiating NEIL1 DNA glycosylase required for chromatin-bound repair complex formation in the human genome increases cellular resistance to oxidative stress.

Sengupta S, Yang C, Hegde ML, Hegde PM, Mitra J, Pandey A, Dutta A, Datarwala AT, Bhakat KK, Mitra S
DNA repair 2018 Jun-Jul;66-67:1-10

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Mussel adhesive protein fused with VE-cadherin domain specifically triggers endothelial cell adhesion.

Yang D, Qiu J, Xu N, Zhao Y, Li T, Ma Q, Huang J, Wang G
Journal of materials chemistry. B 2018 Jun 28;6(24):4151-4163

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Procyanidin B2 mitigates behavioral impairment and protects myelin integrity in cuprizone-induced schizophrenia in mice.

Tian H, Sun W, Zhang Q, Li X, Sang Y, Li J, Niu Y, Ding H
RSC advances 2018 Jun 27;8(42):23835-23846

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Effects of Levonorgestrel and progesterone on Oviductal physiology in mammals.

Li C, Zhang HY, Liang Y, Xia W, Zhu Q, Zhang D, Huang Z, Liang GL, Xue RH, Qi H, He XQ, Yuan JJ, Tan YJ, Huang HF, Zhang J
Reproductive biology and endocrinology : RB&E 2018 Jun 20;16(1):59

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Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.

Fan L, Lu Y, Shen X, Shao H, Suo L, Wu Q
eLife 2018 Jun 18;7

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DRm217 attenuates myocardial ischemia-reperfusion injury via stabilizing plasma membrane Na(+)-K(+)-ATPase, inhibiting Na(+)-K(+)-ATPase/ROS pathway and activating PI3K/Akt and ERK1/2.

Yan X, Xun M, Wu L, Du X, Zhang F, Zheng J
Toxicology and applied pharmacology 2018 Jun 15;349:62-71

---

Long noncoding RNA lncARSR promotes hepatic cholesterol biosynthesis via modulating Akt/SREBP-2/HMGCR pathway.

Huang J, Chen S, Cai D, Bian D, Wang F
Life sciences 2018 Jun 15;203:48-53

---

Underexpression of Receptor for Activated C Kinase 1 (RACK1) in Leukocytes from Patients with Severe Acute Pancreatitis.

Zhang X, Guo J, Wang H, Zhang C, Shi N, Cai W, Jin T, Lin Z, Ma Y, Yang X, Xia Q, Xue P
The Tohoku journal of experimental medicine 2018 Jul;245(3):205-215

---

Generation and propagation of yeast prion [URE3] are elevated under electromagnetic field.

Lian HY, Lin KW, Yang C, Cai P
Cell stress & chaperones 2018 Jul;23(4):581-594

---

Japanese encephalitis virus induces apoptosis by inhibiting Foxo signaling pathway.

Guo F, Yu X, Xu A, Xu J, Wang Q, Guo Y, Wu X, Tang Y, Ding Z, Zhang Y, Gong T, Pan Z, Li S, Kong L
Veterinary microbiology 2018 Jul;220:73-82

---

Membrane topology of rat sodium-coupled neutral amino acid transporter 2 (SNAT2).

Ge Y, Gu Y, Wang J, Zhang Z
Biochimica et biophysica acta. Biomembranes 2018 Jul;1860(7):1460-1469

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Rapamycin and ZSTK474 can have differential effects at different post‑infection time‑points regarding CVB3 replication and CVB3‑induced autophagy.

Chang H, Tian L, Chen J, Tang A, Li C, Li Z, Yang Z
Molecular medicine reports 2018 Jul;18(1):1088-1094

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Chronic stress causes protein kinase C epsilon-aldehyde dehydrogenase 2 signaling pathway perturbation in the rat hippocampus and prefrontal cortex, but not in the myocardium.

Zhang WY, Wang KY, Li YJ, Li YR, Lu RZ
Neural regeneration research 2018 Jul;13(7):1225-1230

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A Polysaccharide Isolated from Dictyophora indusiata Promotes Recovery from Antibiotic-Driven Intestinal Dysbiosis and Improves Gut Epithelial Barrier Function in a Mouse Model.

Kanwal S, Joseph TP, Owusu L, Xiaomeng R, Meiqi L, Yi X
Nutrients 2018 Jul 31;10(8)

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The actin cytoskeletal architecture of estrogen receptor positive breast cancer cells suppresses invasion.

Padilla-Rodriguez M, Parker SS, Adams DG, Westerling T, Puleo JI, Watson AW, Hill SM, Noon M, Gaudin R, Aaron J, Tong D, Roe DJ, Knudsen B, Mouneimne G
Nature communications 2018 Jul 30;9(1):2980

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Myc activity is required for maintenance of the neuromesodermal progenitor signalling network and for segmentation clock gene oscillations in mouse.

Mastromina I, Verrier L, Silva JC, Storey KG, Dale JK
Development (Cambridge, England) 2018 Jul 30;145(14)

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Synthesis and structure-activity relationship studies of MI-2 analogues as MALT1 inhibitors.

Wu G, Wang H, Zhou W, Zeng B, Mo W, Zhu K, Liu R, Zhou J, Chen C, Chen H
Bioorganic & medicinal chemistry 2018 Jul 23;26(12):3321-3344

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Blocking the Thiol at Cysteine-322 Destabilizes Tau Protein and Prevents Its Oligomer Formation.

Chen H, Liu S, Li S, Chen J, Ni J, Liu Q
ACS chemical neuroscience 2018 Jul 18;9(7):1560-1565

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ATXN3 Positively Regulates Type I IFN Antiviral Response by Deubiquitinating and Stabilizing HDAC3.

Feng Q, Miao Y, Ge J, Yuan Y, Zuo Y, Qian L, Liu J, Cheng Q, Guo T, Zhang L, Yu Z, Zheng H
Journal of immunology (Baltimore, Md. : 1950) 2018 Jul 15;201(2):675-687

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Vitamin C increases 5-hydroxymethylcytosine level and inhibits the growth of bladder cancer.

Peng D, Ge G, Gong Y, Zhan Y, He S, Guan B, Li Y, Xu Z, Hao H, He Z, Xiong G, Zhang C, Shi Y, Zhou Y, Ci W, Li X, Zhou L
Clinical epigenetics 2018 Jul 13;10(1):94

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A novel small-molecule activator of Sirtuin-1 induces autophagic cell death/mitophagy as a potential therapeutic strategy in glioblastoma.

Yao ZQ, Zhang X, Zhen Y, He XY, Zhao S, Li XF, Yang B, Gao F, Guo FY, Fu L, Liu XZ, Duan CZ
Cell death & disease 2018 Jul 10;9(7):767

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A reproducible swine model of proximal descending thoracic aortic aneurysm created with intra-adventitial application of elastase.

Tian Y, Zhang W, Sun J, Zhai H, Yu Y, Qi X, Jones JA, Zhong H
Journal of vascular surgery 2018 Jan;67(1):300-308.e2

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Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.

Yang L, Tucker D, Dong Y, Wu C, Lu Y, Li Y, Zhang J, Liu TC, Zhang Q
Experimental neurology 2018 Jan;299(Pt A):86-96

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Hypoxia induces the dysfunction of human endothelial colony-forming cells via HIF-1α signaling.

He M, Ma S, Cai Q, Wu Y, Shao C, Kong H, Wang H, Zeng X, Xie W
Respiratory physiology & neurobiology 2018 Jan;247:87-95

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Mechanism of prolactin inhibition of miR-135b via methylation in goat mammary epithelial cells.

Chen Z, Luo J, Zhang C, Ma Y, Sun S, Zhang T, Loor JJ
Journal of cellular physiology 2018 Jan;233(1):651-662

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Selectivity, cell permeability and oral availability studies of novel bromophenol derivative HPN as protein tyrosine phosphatase 1B inhibitor.

Luo J, Xu Q, Jiang B, Zhang R, Jia X, Li X, Wang L, Guo C, Wu N, Shi D
British journal of pharmacology 2018 Jan;175(1):140-153

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Clinical efficacy of recombinant human latrophilin 3 antibody in the treatment of pediatric asthma.

Liu M, Zhang J, Liu C
Experimental and therapeutic medicine 2018 Jan;15(1):539-547

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PTEN-L promotes type I interferon responses and antiviral immunity.

Cao Y, Wang H, Yang L, Zhang Z, Li C, Yuan X, Bu L, Chen L, Chen Y, Li CM, Guo D
Cellular & molecular immunology 2018 Jan;15(1):48-57

---

Epithelial-mesenchymal crosstalk induces radioresistance in HNSCC cells.

Steinbichler TB, Alshaimaa A, Maria MV, Daniel D, Herbert R, Jozsef D, Ira-Ida S
Oncotarget 2018 Jan 9;9(3):3641-3652

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Wnt/β-catenin pathway promotes acute lung injury induced by LPS through driving the Th17 response in mice.

Cheng L, Zhao Y, Qi D, Li W, Wang D
Biochemical and biophysical research communications 2018 Jan 8;495(2):1890-1895

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Comparative Proteomics Analysis Identifies Cdc42-Cdc42BPA Signaling as Prognostic Biomarker and Therapeutic Target for Colon Cancer Invasion.

Hu HF, Xu WW, Wang Y, Zheng CC, Zhang WX, Li B, He QY
Journal of proteome research 2018 Jan 5;17(1):265-275

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Rhubarb Supplementation Promotes Intestinal Mucosal Innate Immune Homeostasis through Modulating Intestinal Epithelial Microbiota in Goat Kids.

Jiao J, Wu J, Wang M, Zhou C, Zhong R, Tan Z
Journal of agricultural and food chemistry 2018 Jan 31;66(4):1047-1057

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Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.

Zhou P, Liang Y, Zhang H, Jiang H, Feng K, Xu P, Wang J, Wang X, Ding K, Luo C, Liu M, Wang Y
European journal of medicinal chemistry 2018 Jan 20;144:817-842

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SOCE induced calcium overload regulates autophagy in acute pancreatitis via calcineurin activation.

Zhu ZD, Yu T, Liu HJ, Jin J, He J
Cell death & disease 2018 Jan 19;9(2):50

---

Autophagy promotes metastasis and glycolysis by upregulating MCT1 expression and Wnt/β-catenin signaling pathway activation in hepatocellular carcinoma cells.

Fan Q, Yang L, Zhang X, Ma Y, Li Y, Dong L, Zong Z, Hua X, Su D, Li H, Liu J
Journal of experimental & clinical cancer research : CR 2018 Jan 19;37(1):9

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Increased Expression of Cullin 3 in Nasopharyngeal Carcinoma and Knockdown Inhibits Proliferation and Invasion.

Zeng R, Tan G, Li W, Ma Y
Oncology research 2018 Jan 19;26(1):111-122

---

Proteasome Inhibitor Carbobenzoxy-L-Leucyl-L-Leucyl-L-Leucinal (MG132) Enhances Therapeutic Effect of Paclitaxel on Breast Cancer by Inhibiting Nuclear Factor (NF)-κB Signaling.

Zhang Y, Yang B, Zhao J, Li X, Zhang L, Zhai Z
Medical science monitor : international medical journal of experimental and clinical research 2018 Jan 15;24:294-304

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miR-3189-3p Mimics Enhance the Effects of S100A4 siRNA on the Inhibition of Proliferation and Migration of Gastric Cancer Cells by Targeting CFL2.

Bian Y, Guo J, Qiao L, Sun X
International journal of molecular sciences 2018 Jan 13;19(1)

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Uncovering the anticancer mechanism of Compound Kushen Injection against HCC by integrating quantitative analysis, network analysis and experimental validation.

Gao L, Wang KX, Zhou YZ, Fang JS, Qin XM, Du GH
Scientific reports 2018 Jan 12;8(1):624

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Dietary Supplement of Large Yellow Tea Ameliorates Metabolic Syndrome and Attenuates Hepatic Steatosis in db/db Mice.

Teng Y, Li D, Guruvaiah P, Xu N, Xie Z
Nutrients 2018 Jan 12;10(1)

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Repulsive guidance molecule a suppresses angiogenesis after ischemia/reperfusion injury of middle cerebral artery occlusion in rats.

Wang Y, Zhang R, Xing X, Guo J, Xie F, Zhang G, Qin X
Neuroscience letters 2018 Jan 1;662:318-323

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Protein Kinase A/CREB Signaling Prevents Adriamycin-Induced Podocyte Apoptosis via Upregulation of Mitochondrial Respiratory Chain Complexes.

Xie K, Zhu M, Xiang P, Chen X, Kasimumali A, Lu R, Wang Q, Mou S, Ni Z, Gu L, Pang H
Molecular and cellular biology 2018 Jan 1;38(1)

---

Eukaryotic translation initiation factor 2 subunit α (eIF2α) inhibitor salubrinal attenuates paraquat-induced human lung epithelial-like A549 cell apoptosis by regulating the PERK-eIF2α signaling pathway.

Wang R, Sun DZ, Song CQ, Xu YM, Liu W, Liu Z, Dong XS
Toxicology in vitro : an international journal published in association with BIBRA 2018 Feb;46:58-65

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RhPDCD5 combined with dexamethasone increases antitumor activity in multiple myeloma partially via inhibiting the Wnt signalling pathway.

Cheng Q, Liu L, Fu Y, Zhang Y, Yang Y, Liu J
Clinical and experimental pharmacology & physiology 2018 Feb;45(2):140-145

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Aberrant expression of miR-451a contributes to 1,2-dichloroethane-induced hepatic glycerol gluconeogenesis disorder by inhibiting glycerol kinase expression in NIH Swiss mice.

Zeng N, Jiang H, Fan Q, Wang T, Rong W, Li G, Li R, Xu D, Guo T, Wang F, Zeng L, Huang M, Zheng J, Lu F, Chen W, Hu Q, Huang Z, Wang Q
Journal of applied toxicology : JAT 2018 Feb;38(2):292-303

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Ephrin receptor A2 is an epithelial cell receptor for Epstein-Barr virus entry.

Zhang H, Li Y, Wang HB, Zhang A, Chen ML, Fang ZX, Dong XD, Li SB, Du Y, Xiong D, He JY, Li MZ, Liu YM, Zhou AJ, Zhong Q, Zeng YX, Kieff E, Zhang Z, Gewurz BE, Zhao B, Zeng MS
Nature microbiology 2018 Feb;3(2):1-8

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Carnosol-mediated Sirtuin 1 activation inhibits Enhancer of Zeste Homolog 2 to attenuate liver fibrosis.

Zhao H, Wang Z, Tang F, Zhao Y, Feng D, Li Y, Hu Y, Wang C, Zhou J, Tian X, Yao J
Pharmacological research 2018 Feb;128:327-337

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N-oleoylethanolamide suppresses intimal hyperplasia after balloon injury in rats through AMPK/PPARα pathway.

Zhao Y, Liu Y, Jing Z, Peng L, Jin P, Lin Y, Zhou Y, Yang L, Ren J, Xie Q, Jin X
Biochemical and biophysical research communications 2018 Feb 5;496(2):415-421

---

PUM1 promotes ovarian cancer proliferation, migration and invasion.

Guan X, Chen S, Liu Y, Wang LL, Zhao Y, Zong ZH
Biochemical and biophysical research communications 2018 Feb 26;497(1):313-318

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Interferon-alpha enhances the antitumour activity of EGFR-targeted therapies by upregulating RIG-I in head and neck squamous cell carcinoma.

Ma H, Jin S, Yang W, Zhou G, Zhao M, Fang S, Zhang Z, Hu J
British journal of cancer 2018 Feb 20;118(4):509-521

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Involvement of impaired autophagy and mitophagy in Neuro-2a cell damage under hypoxic and/or high-glucose conditions.

Song Y, Du Y, Zou W, Luo Y, Zhang X, Fu J
Scientific reports 2018 Feb 19;8(1):3301

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Hypoxia Activates Src and Promotes Endocytosis Which Decreases MMP-2 Activity and Aggravates Renal Interstitial Fibrosis.

Cheng Z, Liu L, Wang Z, Cai Y, Xu Q, Chen P
International journal of molecular sciences 2018 Feb 15;19(2)

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The RARS-MAD1L1 Fusion Gene Induces Cancer Stem Cell-like Properties and Therapeutic Resistance in Nasopharyngeal Carcinoma.

Zhong Q, Liu ZH, Lin ZR, Hu ZD, Yuan L, Liu YM, Zhou AJ, Xu LH, Hu LJ, Wang ZF, Guan XY, Hao JJ, Lui VWY, Guo L, Mai HQ, Chen MY, Han F, Xia YF, Grandis JR, Zhang X, Zeng MS
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Feb 1;24(3):659-673

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Ajudecumin A from Ajuga ovalifolia var. calantha exhibits anti-inflammatory activity in lipopolysaccharide-activated RAW264.7 murine macrophages and animal models of acute inflammation.

Zhang H, Ren QC, Ren Y, Zhao L, Yang F, Zhang Y, Zhao WJ, Tan YZ, Shen XF
Pharmaceutical biology 2018 Dec;56(1):649-657

---

Effects of garlic polysaccharide on alcoholic liver fibrosis and intestinal microflora in mice.

Wang Y, Guan M, Zhao X, Li X
Pharmaceutical biology 2018 Dec;56(1):325-332

---

Involvement of PINK1/Parkin-mediated mitophagy in paraquat- induced apoptosis in human lung epithelial-like A549 cells.

Sun DZ, Song CQ, Xu YM, Wang R, Liu W, Liu Z, Dong XS
Toxicology in vitro : an international journal published in association with BIBRA 2018 Dec;53:148-159

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Oxymatrine attenuates brain hypoxic-ischemic injury from apoptosis and oxidative stress: role of p-Akt/GSK3β/HO-1/Nrf-2 signaling pathway.

Ge XH, Shao L, Zhu GJ
Metabolic brain disease 2018 Dec;33(6):1869-1875

---

RNF126 Quenches RNF168 Function in the DNA Damage Response.

Zhang L, Wang Z, Shi R, Zhu X, Zhou J, Peng B, Xu X
Genomics, proteomics & bioinformatics 2018 Dec;16(6):428-438

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1,3-Dichloro-2-Propanol inhibits autophagy via P53/AMPK/mTOR pathway in HepG2 cells.

Cheng B, Lu J, Li T, Meng Z, Liu M, Sun M, Guan S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2018 Dec;122:143-150

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Urea transport B gene induces melanoma B16 cell death via activation of p53 and mitochondrial apoptosis.

Liu L, Sun Y, Zhao Y, Wang Q, Guo H, Guo R, Liu Y, Fu S, Zhang L, Li Y, Meng Y
Cancer science 2018 Dec;109(12):3762-3773

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Type 3 innate lymphoid cell: a new player in liver fibrosis progression.

Wang S, Li J, Wu S, Cheng L, Shen Y, Ma W, She W, Yang C, Wang J, Jiang W
Clinical science (London, England : 1979) 2018 Dec 21;132(24):2565-2582

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Long non-coding RNA BRE-AS1 represses non-small cell lung cancer cell growth and survival via up-regulating NR4A3.

Zhang M, Wu J, Zhong W, Zhao Z, Liu Z
Archives of biochemistry and biophysics 2018 Dec 15;660:53-63

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Distinct autophagy-inducing abilities of similar-sized nanoparticles in cell culture and live C. elegans.

Wang Q, Zhou Y, Fu R, Zhu Y, Song B, Zhong Y, Wu S, Shi Y, Wu Y, Su Y, Zhang H, He Y
Nanoscale 2018 Dec 13;10(48):23059-23069

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Protein A from orange-spotted grouper nervous necrosis virus triggers type I interferon production in fish cell.

Huang R, Zhou Q, Shi Y, Zhang J, He J, Xie J
Fish & shellfish immunology 2018 Aug;79:234-243

---

Overcoming resistance to mitochondrial apoptosis by BZML-induced mitotic catastrophe is enhanced by inhibition of autophagy in A549/Taxol cells.

Bai Z, Gao M, Xu X, Zhang H, Xu J, Guan Q, Wang Q, Du J, Li Z, Zuo D, Zhang W, Wu Y
Cell proliferation 2018 Aug;51(4):e12450

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Osteoglycin-induced VEGF Inhibition Enhances T Lymphocytes Infiltrating in Colorectal Cancer.

Hu X, Li YQ, Li QG, Ma YL, Peng JJ, Cai SJ
EBioMedicine 2018 Aug;34:35-45

---

Restoration of 5-hydroxymethylcytosine by ascorbate blocks kidney tumour growth.

Ge G, Peng D, Xu Z, Guan B, Xin Z, He Q, Zhou Y, Li X, Zhou L, Ci W
EMBO reports 2018 Aug;19(8)

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Matrine inhibits the proliferation and migration of lung cancer cells through regulation of the protein kinase B/glycogen synthase kinase-3β signaling pathways.

Xie W, Lu J, Lu Q, Wang X, Long H, Huang J, Guo Z
Experimental and therapeutic medicine 2018 Aug;16(2):723-729

---

TNFSF14/LIGHT, a Non-Canonical NF-κB Stimulus, Induces the HIF Pathway.

D'Ignazio L, Batie M, Rocha S
Cells 2018 Aug 8;7(8)

---

miR-346 Promotes HCC Progression by Suppressing Breast Cancer Metastasis Suppressor 1 Expression.

Guo Z, Li J, Sun J, Sun L, Zhou Y, Yu Z
Oncology research 2018 Aug 23;26(7):1073-1081

---

NRAGE confers poor prognosis and promotes proliferation, invasion, and chemoresistance in gastric cancer.

Jiang X, Jiang X, Yang Z
Gene 2018 Aug 20;668:114-120

---

Selenium-enriched yeast inhibited β-amyloid production and modulated autophagy in a triple transgenic mouse model of Alzheimer's disease.

Song GL, Chen C, Wu QY, Zhang ZH, Zheng R, Chen Y, Jia SZ, Ni JZ
Metallomics : integrated biometal science 2018 Aug 15;10(8):1107-1115

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Effects of Dahuang zhechong pill on doxorubicin-resistant SMMC-7721 xenografts in mice.

Wu L, Cao KX, Ni ZH, Li WD, Chen ZP, Cheng HB, Liu X
Journal of ethnopharmacology 2018 Aug 10;222:71-78

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Uncoupling protein 1 expression in adipocytes derived from skeletal muscle fibro/adipogenic progenitors is under genetic and hormonal control.

Gorski T, Mathes S, Krützfeldt J
Journal of cachexia, sarcopenia and muscle 2018 Apr;9(2):384-399

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Role of TGF-β activated kinase-1 inhibitor on the interaction between macrophages and mesangial cells on the condition of high glucose.

Fan Z, Xu X, Qi X, Wu Y
Immunological investigations 2018 Apr;47(3):303-314

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MiR-151a is involved in the pathogenesis of atopic dermatitis by regulating interleukin-12 receptor β2.

Chen XF, Zhang LJ, Zhang J, Dou X, Shao Y, Jia XJ, Zhang W, Yu B
Experimental dermatology 2018 Apr;27(4):427-432

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TIPE2 is negatively correlated with tissue factor and thrombospondin-1 expression in patients with bronchial asthma.

Shi G, Zhao JW, Sun XX, Ma JF, Wang P, He FC, Ming L
Experimental and therapeutic medicine 2018 Apr;15(4):3449-3454

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The enhancement of siPLK1 penetration across BBB and its anti glioblastoma activity in vivo by magnet and transferrin co-modified nanoparticle.

Liu DZ, Cheng Y, Cai RQ, Wang Bd WW, Cui H, Liu M, Zhang BL, Mei QB, Zhou SY
Nanomedicine : nanotechnology, biology, and medicine 2018 Apr;14(3):991-1003

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Identification of novel Nrf2 activators from Cinnamomum chartophyllum H.W. Li and their potential application of preventing oxidative insults in human lung epithelial cells.

Zhou MX, Li GH, Sun B, Xu YW, Li AL, Li YR, Ren DM, Wang XN, Wen XS, Lou HX, Shen T
Redox biology 2018 Apr;14:154-163

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Catalpol ameliorates hepatic insulin resistance in type 2 diabetes through acting on AMPK/NOX4/PI3K/AKT pathway.

Yan J, Wang C, Jin Y, Meng Q, Liu Q, Liu Z, Liu K, Sun H
Pharmacological research 2018 Apr;130:466-480

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Protective effect of methylallyl sulfone in the development of cigarette smoke extract-induced apoptosis in rats and HFL-1 cells.

Li A, Liu Y, Zhu X, Sun X, Feng X, Li D, Zhang J, Zhu M, Zhao Z
Biochemical and biophysical research communications 2018 Apr 6;498(3):627-632

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Smurf1 restricts the antiviral function mediated by USP25 through promoting its ubiquitination and degradation.

Qian G, Hu X, Li G, Ding Y, Zhu L, Zheng H, Li M, Li Z, Pan J, Li Y, Li G, Yang C, Liu Y, Xie Y, Lv H
Biochemical and biophysical research communications 2018 Apr 6;498(3):537-543

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GRASP55 Senses Glucose Deprivation through O-GlcNAcylation to Promote Autophagosome-Lysosome Fusion.

Zhang X, Wang L, Lak B, Li J, Jokitalo E, Wang Y
Developmental cell 2018 Apr 23;45(2):245-261.e6

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The GABA(A) Receptor α2 Subunit Activates a Neuronal TLR4 Signal in the Ventral Tegmental Area that Regulates Alcohol and Nicotine Abuse.

Balan I, Warnock KT, Puche A, Gondre-Lewis MC, June H, Aurelian L
Brain sciences 2018 Apr 21;8(4)

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Pathological Features of Staphylococcus aureus Induced Mastitis in Dairy Cows and Isobaric-Tags-for-Relative-and-Absolute-Quantitation Proteomic Analyses.

Chen Z, Xia H, Shen H, Xu X, Arbab AAI, Li M, Zhang H, Mao Y, Yang Z
Journal of agricultural and food chemistry 2018 Apr 18;66(15):3880-3890

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Role of silent information regulator 1 in the protective effect of hydrogen sulfide on homocysteine-induced cognitive dysfunction: Involving reduction of hippocampal ER stress.

Tang YY, Wang AP, Wei HJ, Li MH, Zou W, Li X, Wang CY, Zhang P, Tang XQ
Behavioural brain research 2018 Apr 16;342:35-42

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Differential CRABP-II and FABP5 expression patterns and implications for medulloblastoma retinoic acid sensitivity.

Zhang S, Liu H, Li H, Wu M, Yu Y, Li F, Cheng X
RSC advances 2018 Apr 11;8(25):14048-14055

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Nogo-B receptor promotes epithelial-mesenchymal transition in non-small cell lung cancer cells through the Ras/ERK/Snail1 pathway.

Wu D, Zhao B, Qi X, Peng F, Fu H, Chi X, Miao QR, Shao S
Cancer letters 2018 Apr 1;418:135-146

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GRHL2 suppresses tumor metastasis via regulation of transcriptional activity of RhoG in non-small cell lung cancer.

Pan X, Zhang R, Xie C, Gan M, Yao S, Yao Y, Jin J, Han T, Huang Y, Gong Y, Wang J, Yu B
American journal of translational research 2017;9(9):4217-4226

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Silencing Rab14 represses the proliferation and migration of oral squamous cell carcinoma, and enhances cisplatin sensitivity.

Lian Q, Ma DM, Chen MG, Chen K, Li XJ
American journal of translational research 2017;9(9):4195-4205

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3-Mercaptopyruvate Sulfurtransferase, Not Cystathionine β-Synthase Nor Cystathionine γ-Lyase, Mediates Hypoxia-Induced Migration of Vascular Endothelial Cells.

Tao B, Wang R, Sun C, Zhu Y
Frontiers in pharmacology 2017;8:657

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Antimycobacterial and Anti-inflammatory Mechanisms of Baicalin via Induced Autophagy in Macrophages Infected with Mycobacterium tuberculosis.

Zhang Q, Sun J, Wang Y, He W, Wang L, Zheng Y, Wu J, Zhang Y, Jiang X
Frontiers in microbiology 2017;8:2142

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Variant Amino Acid Residues Alter the Enzyme Activity of Peanut Type 2 Diacylglycerol Acyltransferases.

Zheng L, Shockey J, Bian F, Chen G, Shan L, Li X, Wan S, Peng Z
Frontiers in plant science 2017;8:1751

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Iridoids with Genipin Stem Nucleus Inhibit Lipopolysaccharide-Induced Inflammation and Oxidative Stress by Blocking the NF-κB Pathway in Polycystic Ovary Syndrome.

Zuo T, Zhu M, Xu W, Wang Z, Song H
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(5):1855-1865

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The USP7 Inhibitor P5091 Induces Cell Death in Ovarian Cancers with Different P53 Status.

Wang M, Zhang Y, Wang T, Zhang J, Zhou Z, Sun Y, Wang S, Shi Y, Luan X, Zhang Y, Wang Y, Wang Y, Zou Z, Kang L, Liu H
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(5):1755-1766

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α-Lipoic Acid Promotes Neurological Recovery After Ischemic Stroke by Activating the Nrf2/HO-1 Pathway to Attenuate Oxidative Damage.

Lv C, Maharjan S, Wang Q, Sun Y, Han X, Wang S, Mao Z, Xin Y, Zhang B
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(3):1273-1287

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Targeted kinase inhibition relieves slowness and tremor in a Drosophila model of LRRK2 Parkinson's disease.

Cording AC, Shiaelis N, Petridi S, Middleton CA, Wilson LG, Elliott CJH
NPJ Parkinson's disease 2017;3:34

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Endoplasmic Reticulum Stress Is Involved in Cochlear Cell Apoptosis in a Cisplatin-Induced Ototoxicity Rat Model.

Zong S, Liu T, Wan F, Chen P, Luo P, Xiao H
Audiology & neuro-otology 2017;22(3):160-168

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Role of Zebrafish fhl1A in Satellite Cell and Skeletal Muscle Development.

Chen F, Yuan W, Mo X, Zhuang J, Wang Y, Chen J, Jiang Z, Zhu X, Zeng Q, Wan Y, Li F, Shi Y, Cao L, Fan X, Luo S, Ye X, Chen Y, Dai G, Gao J, Wang X, Xie H, Zhu P, Li Y, Wu X
Current molecular medicine 2017;17(9):627-636

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XRCC5 cooperates with p300 to promote cyclooxygenase-2 expression and tumor growth in colon cancers.

Zhang Z, Zheng F, Yu Z, Hao J, Chen M, Yu W, Guo W, Chen Y, Huang W, Duan Z, Deng W
PloS one 2017;12(10):e0186900

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miR-125b-5p functions as a tumor suppressor gene partially by regulating HMGA2 in esophageal squamous cell carcinoma.

Mei LL, Wang WJ, Qiu YT, Xie XF, Bai J, Shi ZZ
PloS one 2017;12(10):e0185636

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Autophagy promotes degradation of polyethyleneimine-alginate nanoparticles in endothelial progenitor cells.

Wang GD, Tan YZ, Wang HJ, Zhou P
International journal of nanomedicine 2017;12:6661-6675

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Curcumin Activates AMPK Pathway and Regulates Lipid Metabolism in Rats Following Prolonged Clozapine Exposure.

Liu Z, Cui C, Xu P, Dang R, Cai H, Liao D, Yang M, Feng Q, Yan X, Jiang P
Frontiers in neuroscience 2017;11:558

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Paeoniflorin attenuates incipient diabetic nephropathy in streptozotocin-induced mice by the suppression of the Toll-like receptor-2 signaling pathway.

Shao YX, Xu XX, Wang K, Qi XM, Wu YG
Drug design, development and therapy 2017;11:3221-3233

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Roux-en-Y Gastric Bypass Improves Hepatic Glucose Metabolism Involving Down-Regulation of Protein Tyrosine Phosphatase 1B in Obese Rats.

Mu S, Liu J, Guo W, Zhang S, Xiao X, Wang Z, Zhang J
Obesity facts 2017;10(3):191-206

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Metabolic reprogramming induced by inhibition of SLC2A1 suppresses tumor progression in lung adenocarcinoma.

Wang Y, Shi S, Ding Y, Wang Z, Liu S, Yang J, Xu T
International journal of clinical and experimental pathology 2017;10(11):10759-10769

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HOXD-AS1 functions as an oncogenic ceRNA to promote NSCLC cell progression by sequestering miR-147a.

Wang Q, Jiang S, Song A, Hou S, Wu Q, Qi L, Gao X
OncoTargets and therapy 2017;10:4753-4763

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Transcription Factor NFAT5 Promotes Glioblastoma Cell-driven Angiogenesis via SBF2-AS1/miR-338-3p-Mediated EGFL7 Expression Change.

Yu H, Zheng J, Liu X, Xue Y, Shen S, Zhao L, Li Z, Liu Y
Frontiers in molecular neuroscience 2017;10:301

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Identification of Flavin-Containing Monooxygenase 5 (FMO5) as a Regulator of Glucose Homeostasis and a Potential Sensor of Gut Bacteria.

Scott F, Gonzalez Malagon SG, O'Brien BA, Fennema D, Veeravalli S, Coveney CR, Phillips IR, Shephard EA
Drug metabolism and disposition: the biological fate of chemicals 2017 Sep;45(9):982-989

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Visfatin induces the apoptosis of endothelial progenitor cells via the induction of pro-inflammatory mediators through the NF-κB pathway.

Sun L, Chen S, Gao H, Ren L, Song G
International journal of molecular medicine 2017 Sep;40(3):637-646

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Mechanism of Lycium barbarum polysaccharides on primary cultured rat hippocampal neurons.

Zhao P, Ma NT, Chang RY, Li YX, Hao YJ, Yang WL, Zheng J, Niu Y, Sun T, Yu JQ
Cell and tissue research 2017 Sep;369(3):455-465

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Downregulation of serum RAB27B confers improved prognosis and is associated with hepatocellular carcinoma progression through PI3K-AKT-P21 signaling.

Yang X, Ye X, Sun L, Gao F, Li Y, Ji X, Wang X, Feng Y, Wang X
Oncotarget 2017 Sep 22;8(37):61118-61132

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Vegetally localised Vrtn functions as a novel repressor to modulate bmp2b transcription during dorsoventral patterning in zebrafish.

Shao M, Wang M, Liu YY, Ge YW, Zhang YJ, Shi DL
Development (Cambridge, England) 2017 Sep 15;144(18):3361-3374

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Dendrobium nobile Lindl. alkaloids regulate metabolism gene expression in livers of mice.

Xu YY, Xu YS, Wang Y, Wu Q, Lu YF, Liu J, Shi JS
The Journal of pharmacy and pharmacology 2017 Oct;69(10):1409-1417

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APPL1 promotes the migration of gastric cancer cells by regulating Akt2 phosphorylation.

Liu Y, Zhang C, Zhao L, Du N, Hou N, Song T, Huang C
International journal of oncology 2017 Oct;51(4):1343-1351

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Thrombospondin-1 Production Regulates the Inflammatory Cytokine Secretion in THP-1 Cells Through NF-κB Signaling Pathway.

Xing T, Wang Y, Ding WJ, Li YL, Hu XD, Wang C, Ding A, Shen JL
Inflammation 2017 Oct;40(5):1606-1621

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An Important Function of Petrosiol E in Inducing the Differentiation of Neuronal Progenitors and in Protecting Them against Oxidative Stress.

Liu J, Wang L, Du Y, Liu S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2017 Oct;4(10):1700089

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Anti-inflammatory capacity of Lactobacillus rhamnosus GG in monophasic variant Salmonella infected piglets is correlated with impeding NLRP6-mediated host inflammatory responses.

Yu J, Zhu YH, Yang GY, Zhang W, Zhou D, Su JH, Wang JF
Veterinary microbiology 2017 Oct;210:91-100

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Ovarian cancer proliferation and apoptosis are regulated by human transfer RNA methyltransferase 9-likevia LIN9.

Chen HM, Wang J, Zhang YF, Gao YH
Oncology letters 2017 Oct;14(4):4461-4466

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High expression of IL-4R enhances proliferation and invasion of hepatocellular carcinoma cells.

Guo C, Ouyang Y, Cai J, Xiong L, Chen Y, Zeng X, Liu A
The International journal of biological markers 2017 Oct 31;32(4):e384-e390

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The role of long non-coding RNA PCA3 in epithelial ovarian carcinoma tumorigenesis and progression.

Liu Y, Zong ZH, Guan X, Wang LL, Zhao Y
Gene 2017 Oct 30;633:42-47

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Inhibition of Starvation-Triggered Endoplasmic Reticulum Stress, Autophagy, and Apoptosis in ARPE-19 Cells by Taurine through Modulating the Expression of Calpain-1 and Calpain-2.

Zhang Y, Ren S, Liu Y, Gao K, Liu Z, Zhang Z
International journal of molecular sciences 2017 Oct 14;18(10)

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Evidence for a direct cross-talk between malic enzyme and the pentose phosphate pathway via structural interactions.

Yao P, Sun H, Xu C, Chen T, Zou B, Jiang P, Du W
The Journal of biological chemistry 2017 Oct 13;292(41):17113-17120

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Ligand-dependent EphA7 signaling inhibits prostate tumor growth and progression.

Li S, Wu Z, Ma P, Xu Y, Chen Y, Wang H, He P, Kang Z, Yin L, Zhao Y, Zhang X, Xu X, Ma X, Guan M
Cell death & disease 2017 Oct 12;8(10):e3122

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Fluoride-Induced Autophagy via the Regulation of Phosphorylation of Mammalian Targets of Rapamycin in Mice Leydig Cells.

Zhang J, Zhu Y, Shi Y, Han Y, Liang C, Feng Z, Zheng H, Eng M, Wang J
Journal of agricultural and food chemistry 2017 Oct 11;65(40):8966-8976

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MicroRNA-23a promotes pancreatic cancer metastasis by targeting epithelial splicing regulator protein 1.

Wu G, Li Z, Jiang P, Zhang X, Xu Y, Chen K, Li X
Oncotarget 2017 Oct 10;8(47):82854-82871

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Epigenetic silencing of ASPP1 confers 5-FU resistance in clear cell renal cell carcinoma by preventing p53 activation.

Wang X, Cheng Y, Zhu Y, Li H, Ge W, Wu X, Zhao K, Yuan J, Li Z, Jiang S, Han Z, Jiang Q, Wu Q, Liu T, Zhang C, Yu M, Hu Y
International journal of cancer 2017 Oct 1;141(7):1422-1433

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Cryptotanshinone sensitizes antitumor effect of paclitaxel on tongue squamous cell carcinoma growth by inhibiting the JAK/STAT3 signaling pathway.

Wang Y, Lu HL, Liu YD, Yang LY, Jiang QK, Zhu XJ, Fan HN, Qian Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Nov;95:1388-1396

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Spatiotemporal Expression of Bcl-2/Bax and Neural Cell Apoptosis in the Developing Lumbosacral Spinal Cord of Rat Fetuses with Anorectal Malformations.

Yang Z, Geng Y, Yao Z, Jia H, Bai Y, Wang W
Neurochemical research 2017 Nov;42(11):3160-3169

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Sialic acid-modified solid lipid nanoparticles as vascular endothelium-targeting carriers for ischemia-reperfusion-induced acute renal injury.

Hu JB, Song GL, Liu D, Li SJ, Wu JH, Kang XQ, Qi J, Jin FY, Wang XJ, Xu XL, Ying XY, Yu L, You J, Du YZ
Drug delivery 2017 Nov;24(1):1856-1867

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Lack of BACE1 S-palmitoylation reduces amyloid burden and mitigates memory deficits in transgenic mouse models of Alzheimer's disease.

Andrew RJ, Fernandez CG, Stanley M, Jiang H, Nguyen P, Rice RC, Buggia-Prévot V, De Rossi P, Vetrivel KS, Lamb R, Argemi A, Allaert ES, Rathbun EM, Krause SV, Wagner SL, Parent AT, Holtzman DM, Thinakaran G
Proceedings of the National Academy of Sciences of the United States of America 2017 Nov 7;114(45):E9665-E9674

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Cell-autonomous adiposity through increased cell surface GLUT4 due to ankyrin-B deficiency.

Lorenzo DN, Bennett V
Proceedings of the National Academy of Sciences of the United States of America 2017 Nov 28;114(48):12743-12748

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Proteomics and metabolomics analysis of hepatic mitochondrial metabolism in alcohol-preferring and non-preferring rats.

Zeng HL, Yang Q, Du H, Li H, Shen Y, Liu T, Chen X, Kamal GM, Guan Q, Cheng L, Wang J, Xu F
Oncotarget 2017 Nov 24;8(60):102020-102032

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Copper or/and arsenic induce oxidative stress-cascaded, nuclear factor kappa B-dependent inflammation and immune imbalance, trigging heat shock response in the kidney of chicken.

Wang Y, Zhao H, Shao Y, Liu J, Li J, Xing M
Oncotarget 2017 Nov 17;8(58):98103-98116

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Hydrogen Sulfide Inhibits Chronic Unpredictable Mild Stress-Induced Depressive-Like Behavior by Upregulation of Sirt-1: Involvement in Suppression of Hippocampal Endoplasmic Reticulum Stress.

Liu SY, Li D, Zeng HY, Kan LY, Zou W, Zhang P, Gu HF, Tang XQ
The international journal of neuropsychopharmacology 2017 Nov 1;20(11):867-876

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Inhibition of tissue transglutaminase attenuates lipopolysaccharide-induced inflammation in glial cells through AKT/mTOR signal pathway.

Ding Y, Zhang J, Wang R
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:1310-1319

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FGF7/FGFR2 signal promotes invasion and migration in human gastric cancer through upregulation of thrombospondin-1.

Huang T, Wang L, Liu D, Li P, Xiong H, Zhuang L, Sun L, Yuan X, Qiu H
International journal of oncology 2017 May;50(5):1501-1512

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Embelin attenuates adipogenesis and lipogenesis through activating canonical Wnt signaling and inhibits high-fat diet-induced obesity.

Gao Y, Li J, Xu X, Wang S, Yang Y, Zhou J, Zhang L, Zheng F, Li X, Wang B
International journal of obesity (2005) 2017 May;41(5):729-738

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Preliminary evaluation for Bit1 as a potential biomarker for squamous cell carcinoma and adenocarcinoma of esophagus.

Chen J, Liu H, Gao P, Hui Y, Yang Z, Zhang X, Xu P, Tian F, Fan T
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 May;39(5):1010428317708267

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Sulforaphane-cysteine induces apoptosis by sustained activation of ERK1/2 and caspase 3 in human glioblastoma U373MG and U87MG cells.

Wu S, Zhou Y, Yang G, Tian H, Geng Y, Hu Y, Lin K, Wu W
Oncology reports 2017 May;37(5):2829-2838

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oxLDL antibody inhibits MCP-1 release in monocytes/macrophages by regulating Ca(2+) /K(+) channel flow.

Su J, Zhou H, Liu X, Nilsson J, Fredrikson GN, Zhao M
Journal of cellular and molecular medicine 2017 May;21(5):929-940

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TET3-mediated DNA oxidation promotes ATR-dependent DNA damage response.

Jiang D, Wei S, Chen F, Zhang Y, Li J
EMBO reports 2017 May;18(5):781-796

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Menin enhances c-Myc-mediated transcription to promote cancer progression.

Wu G, Yuan M, Shen S, Ma X, Fang J, Zhu L, Sun L, Liu Z, He X, Huang D, Li T, Li C, Wu J, Hu X, Li Z, Song L, Qu K, Zhang H, Gao P
Nature communications 2017 May 5;8:15278

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Thyroid stimulating hormone increases hepatic gluconeogenesis via CRTC2.

Li Y, Wang L, Zhou L, Song Y, Ma S, Yu C, Zhao J, Xu C, Gao L
Molecular and cellular endocrinology 2017 May 5;446:70-80

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Longikaurin A, a natural ent-kaurane, suppresses stemness in nasopharyngeal carcinoma cells.

Yuan Y, Du Y, Hu XY, Liu MY, Du JK, Liu XM, Yu HE, Wang TZ, Pu JX, Zhong Q, Zou QF
Oncology letters 2017 Mar;13(3):1672-1680

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Hypoxia promotes chemotherapy resistance by down-regulating SKA1 gene expression in human osteosarcoma.

Ma Q, Zhang Y, Liu T, Jiang K, Wen Y, Fan Q, Qiu X
Cancer biology & therapy 2017 Mar 4;18(3):177-185

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miR-148a and miR-17-5p synergistically regulate milk TAG synthesis via PPARGC1A and PPARA in goat mammary epithelial cells.

Chen Z, Luo J, Sun S, Cao D, Shi H, Loor JJ
RNA biology 2017 Mar 4;14(3):326-338

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MicroRNA-17-92 Regulates the Transcription Factor E2F3b during Myogenesis In Vitro and In Vivo.

Tang Z, Liu N, Luo L, Kang K, Li L, Ni R, Qiu H, Gou D
International journal of molecular sciences 2017 Mar 31;18(4)

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Probiotics may delay the progression of nonalcoholic fatty liver disease by restoring the gut microbiota structure and improving intestinal endotoxemia.

Xue L, He J, Gao N, Lu X, Li M, Wu X, Liu Z, Jin Y, Liu J, Xu J, Geng Y
Scientific reports 2017 Mar 28;7:45176

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Anti-tumor effect of evodiamine by inducing Akt-mediated apoptosis in hepatocellular carcinoma.

Yang F, Shi L, Liang T, Ji L, Zhang G, Shen Y, Zhu F, Xu L
Biochemical and biophysical research communications 2017 Mar 25;485(1):54-61

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AMPK/α-Ketoglutarate Axis Regulates Intestinal Water and Ion Homeostasis in Young Pigs.

He L, Huang N, Li H, Tian J, Zhou X, Li T, Yao K, Wu G, Yin Y
Journal of agricultural and food chemistry 2017 Mar 22;65(11):2287-2298

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Upregulation of microRNA-574-3p in a human gastric cancer cell line AGS by TGF-β1.

Zhang R, Wang M, Sui P, Ding L, Yang Q
Gene 2017 Mar 20;605:63-69

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A coumarin-based fluorescence resonance energy transfer probe targeting matrix metalloproteinase-2 for the detection of cervical cancer.

He G, Yang L, Qian X, Li J, Yuan Z, Li C
International journal of molecular medicine 2017 Jun;39(6):1571-1579

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Sulforaphane prevents bleomycin‑induced pulmonary fibrosis in mice by inhibiting oxidative stress via nuclear factor erythroid 2‑related factor‑2 activation.

Yan B, Ma Z, Shi S, Hu Y, Ma T, Rong G, Yang J
Molecular medicine reports 2017 Jun;15(6):4005-4014

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Cerebrolysin alleviates cognitive deficits induced by chronic cerebral hypoperfusion by increasing the levels of plasticity-related proteins and decreasing the levels of apoptosis-related proteins in the rat hippocampus.

Liu Z, Hu M, Lu P, Wang H, Qi Q, Xu J, Xiao Y, Fan M, Jia Y, Zhang D
Neuroscience letters 2017 Jun 9;651:72-78

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CADASIL mutant NOTCH3(R90C) decreases the viability of HS683 oligodendrocytes via apoptosis.

Tang M, Shi C, Song B, Yang J, Yang T, Mao C, Li Y, Liu X, Zhang S, Wang H, Luo H, Xu Y
Molecular biology reports 2017 Jul;44(3):273-280

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The MBNL3 splicing factor promotes hepatocellular carcinoma by increasing PXN expression through the alternative splicing of lncRNA-PXN-AS1.

Yuan JH, Liu XN, Wang TT, Pan W, Tao QF, Zhou WP, Wang F, Sun SH
Nature cell biology 2017 Jul;19(7):820-832

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Malvidin and cyanidin derivatives from açai fruit (Euterpe oleracea Mart.) counteract UV-A-induced oxidative stress in immortalized fibroblasts.

Petruk G, Illiano A, Del Giudice R, Raiola A, Amoresano A, Rigano MM, Piccoli R, Monti DM
Journal of photochemistry and photobiology. B, Biology 2017 Jul;172:42-51

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Selenium-Containing Polysaccharide-Protein Complex in Se-Enriched Ulva fasciata Induces Mitochondria-Mediated Apoptosis in A549 Human Lung Cancer Cells.

Sun X, Zhong Y, Luo H, Yang Y
Marine drugs 2017 Jul 16;15(7)

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Deubiquitinase USP33 is negatively regulated by β-TrCP through ubiquitin-dependent proteolysis.

Cheng Q, Yuan Y, Li L, Guo T, Miao Y, Ren Y, Liu J, Feng Q, Wang X, Zhao P, Zuo Y, Qian L, Zhang L, Zheng H
Experimental cell research 2017 Jul 1;356(1):1-7

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Transcription regulator TRIP-Br2 mediates ER stress-induced brown adipocytes dysfunction.

Qiang G, Whang Kong H, Gil V, Liew CW
Scientific reports 2017 Jan 9;7:40215

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The role of the ATM/Chk/P53 pathway in mediating DNA damage in hand-foot syndrome induced by PLD.

Yang J, Qiao L, Zeng Z, Wang J, Zhu T, Wei J, Wu M, Ye S, Huang X, Ma D, Liu R, Gao Q
Toxicology letters 2017 Jan 4;265:131-139

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Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin.

Xue C, Wang C, Sun Y, Meng Q, Liu Z, Huo X, Sun P, Sun H, Ma X, Ma X, Peng J, Liu K
Oncotarget 2017 Jan 31;8(5):8622-8632

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Knockdown of TREM-1 suppresses IL-1β-induced chondrocyte injury via inhibiting the NF-κB pathway.

Tang J, Dong Q
Biochemical and biophysical research communications 2017 Jan 22;482(4):1240-1245

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Inhibition of store-operated Ca(2+) entry counteracts the apoptosis of nasopharyngeal carcinoma cells induced by sodium butyrate.

Huang W, Ren C, Huang G, Liu J, Liu W, Wang L, Zhu B, Feng X, Shi J, Li J, Xia X, Jia W, Chen J, Chen Y, Jiang X
Oncology letters 2017 Feb;13(2):921-929

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Transdifferentiation of human male germline stem cells to hepatocytes in vivo via the transplantation under renal capsules.

Chen Z, Niu M, Sun M, Yuan Q, Yao C, Hou J, Wang H, Wen L, Fu H, Zhou F, Li Z, He Z
Oncotarget 2017 Feb 28;8(9):14576-14592

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Calycosin attenuates triglyceride accumulation and hepatic fibrosis in murine model of non-alcoholic steatohepatitis via activating farnesoid X receptor.

Duan X, Meng Q, Wang C, Liu Z, Liu Q, Sun H, Sun P, Yang X, Huo X, Peng J, Liu K
Phytomedicine : international journal of phytotherapy and phytopharmacology 2017 Feb 15;25:83-92

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Single tumor-initiating cells evade immune clearance by recruiting type II macrophages.

Guo X, Zhao Y, Yan H, Yang Y, Shen S, Dai X, Ji X, Ji F, Gong XG, Li L, Bai X, Feng XH, Liang T, Ji J, Chen L, Wang H, Zhao B
Genes & development 2017 Feb 1;31(3):247-259

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Ontogeny, aging, and gender-related changes in hepatic multidrug resistant protein genes in rats.

Zhu QN, Hou WY, Xu SF, Lu YF, Liu J
Life sciences 2017 Feb 1;170:108-114

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Altered Expression of TXNIP in the peripheral leukocytes of patients with coronary atherosclerotic heart disease.

Zhang Y, Huang J, Yang X, Sun X, Xu Q, Wang B, Zhong P, Wei Z
Medicine 2017 Dec;96(49):e9108

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Effects of polysaccharide from Physalis alkekengi var. francheti on liver injury and intestinal microflora in type-2 diabetic mice.

Zhao X, Chen Z, Yin Y, Li X
Pharmaceutical biology 2017 Dec;55(1):2020-2025

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Induction of autophagy by an oleanolic acid derivative, SZC017, promotes ROS-dependent apoptosis through Akt and JAK2/STAT3 signaling pathway in human lung cancer cells.

Song Y, Kong L, Sun B, Gao L, Chu P, Ahsan A, Qaed E, Lin Y, Peng J, Ma X, Zhang J, Wang S, Tang Z
Cell biology international 2017 Dec;41(12):1367-1378

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Glucose potentiates β-cell function by inducing Tph1 expression in rat islets.

Zhang Y, Deng R, Yang X, Xu W, Liu Y, Li F, Zhang J, Tang H, Ji X, Bi Y, Wang X, Zhou L, Ning G
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Dec;31(12):5342-5355

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POSH participates in epileptogenesis by increasing the surface expression of the NMDA receptor: a promising therapeutic target for epilepsy.

Wang X, Tian X, Yang Y, Lu X, Li Y, Ma Y, Zhang Y, Zheng F, Lu S, Xu D, Xu X, Wang W, Wang X
Expert opinion on therapeutic targets 2017 Dec;21(12):1083-1094

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Regulation of AMH by oocyte-specific growth factors in human primary cumulus cells.

Convissar S, Armouti M, Fierro MA, Winston NJ, Scoccia H, Zamah AM, Stocco C
Reproduction (Cambridge, England) 2017 Dec;154(6):745-753

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Effects of dimethyl carbonate-induced autophagic activation on follicular development in the mouse ovary.

Tang Z, Zhang Z, Tang Y, Qi L, Yang F, Wang Z
Experimental and therapeutic medicine 2017 Dec;14(6):5981-5989

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MicroRNA-30e Functions as a Tumor Suppressor in Cervical Carcinoma Cells through Targeting GALNT7.

Wu H, Chen J, Li D, Liu X, Li L, Wang K
Translational oncology 2017 Dec;10(6):876-885

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Piperlongumine suppresses bladder cancer invasion via inhibiting epithelial mesenchymal transition and F-actin reorganization.

Liu D, Qiu XY, Wu X, Hu DX, Li CY, Yu SB, Pan F, Chen XQ
Biochemical and biophysical research communications 2017 Dec 9;494(1-2):165-172

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Salvianolic acid B protects against lipopolysaccharide-induced behavioral deficits and neuroinflammatory response: involvement of autophagy and NLRP3 inflammasome.

Jiang P, Guo Y, Dang R, Yang M, Liao D, Li H, Sun Z, Feng Q, Xu P
Journal of neuroinflammation 2017 Dec 6;14(1):239

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Rho/ROCK Pathway Regulates Migration and Invasion of Esophageal Squamous Cell Carcinoma by Regulating Caveolin-1.

Liu Z, Yu J, Wu R, Tang S, Cai X, Guo G, Chen S
Medical science monitor : international medical journal of experimental and clinical research 2017 Dec 30;23:6174-6185

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CAPE-pNO(2) ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.

Wang X, Li D, Fan L, Xiao Q, Zuo H, Li Z
Oncotarget 2017 Dec 29;8(70):114506-114525

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Synergistic inhibition of tumor growth by combination treatment with drugs against different subpopulations of glioblastoma cells.

Chang CH, Liu WT, Hung HC, Gean CY, Tsai HM, Su CL, Gean PW
BMC cancer 2017 Dec 29;17(1):905

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Discovery of a Small-Molecule Bromodomain-Containing Protein 4 (BRD4) Inhibitor That Induces AMP-Activated Protein Kinase-Modulated Autophagy-Associated Cell Death in Breast Cancer.

Ouyang L, Zhang L, Liu J, Fu L, Yao D, Zhao Y, Zhang S, Wang G, He G, Liu B
Journal of medicinal chemistry 2017 Dec 28;60(24):9990-10012

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Cadherin 6 is activated by Epstein-Barr virus LMP1 to mediate EMT and metastasis as an interplay node of multiple pathways in nasopharyngeal carcinoma.

Zuo LL, Zhang J, Liu LZ, Zhou Q, Du SJ, Xin SY, Ning ZP, Yang J, Yu HB, Yue WX, Wang J, Zhu FX, Li GY, Lu JH
Oncogenesis 2017 Dec 22;6(12):402

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Ultrasound reverses chemoresistance in breast cancer stem cell like cells by altering ABCG2 expression.

Guo L, Zheng P, Fan H, Wang H, Xu W, Zhou W
Bioscience reports 2017 Dec 22;37(6)

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Indomethacin-based stimuli-responsive micelles combined with paclitaxel to overcome multidrug resistance.

Wang S, Tan X, Li S, Zhou Y, Geng P, Hua A, Deng A, Yu Z
Oncotarget 2017 Dec 19;8(67):111281-111294

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De novo, deleterious sequence variants that alter the transcriptional activity of the homeoprotein PBX1 are associated with intellectual disability and pleiotropic developmental defects.

Slavotinek A, Risolino M, Losa M, Cho MT, Monaghan KG, Schneidman-Duhovny D, Parisotto S, Herkert JC, Stegmann APA, Miller K, Shur N, Chui J, Muller E, DeBrosse S, Szot JO, Chapman G, Pachter NS, Winlaw DS, Mendelsohn BA, Dalton J, Sarafoglou K, Karachunski PI, Lewis JM, Pedro H, Dunwoodie SL, Selleri L, Shieh J
Human molecular genetics 2017 Dec 15;26(24):4849-4860

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Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells.

Wei X, Ye J, Shang Y, Chen H, Liu S, Liu L, Wang R
Oncotarget 2017 Dec 12;8(65):109301-109318

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Adeno-associated virus 9-mediated Cdk5 inhibitory peptide reverses pathologic changes and behavioral deficits in the Alzheimer's disease mouse model.

He Y, Pan S, Xu M, He R, Huang W, Song P, Huang J, Zhang HT, Hu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Aug;31(8):3383-3392

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Effect of GAPT extract on expression of tau protein and its phosphorylation related enzymes in hippocampal neurons of APPV717I transgenic mice.

Ni JN, Shi J, Zhang XK, Yang YC, Liu XM, Wei MQ, Li T, Wang PW, Tian JZ, Wang YY
Chinese journal of integrative medicine 2017 Aug;23(8):605-610

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Ubiquitin C-terminal hydrolase-L3 promotes interferon antiviral activity by stabilizing type I-interferon receptor.

Zhao P, Guo T, Qian L, Wang X, Yuan Y, Cheng Q, Zuo Y, Liu J, Miao Y, Feng Q, Zhang L, Wu S, Zheng H
Antiviral research 2017 Aug;144:120-129

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Palbociclib induces activation of AMPK and inhibits hepatocellular carcinoma in a CDK4/6-independent manner.

Hsieh FS, Chen YL, Hung MH, Chu PY, Tsai MH, Chen LJ, Hsiao YJ, Shih CT, Chang MJ, Chao TI, Shiau CW, Chen KF
Molecular oncology 2017 Aug;11(8):1035-1049

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NFATc3 mediates the sensitivity of gastric cancer cells to arsenic sulfide.

Zhang X, Kang T, Zhang L, Tong Y, Ding W, Chen S
Oncotarget 2017 Aug 8;8(32):52735-52745

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Apoptosis pattern and alterations of expression of apoptosis-related factors of supporting cells in Kölliker's organ in vivo in early stage after birth in rats.

Liu J, Cai L, He Y, Yang J
European journal of histochemistry : EJH 2017 Aug 7;61(3):2706

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Enteric dysbiosis-linked gut barrier disruption triggers early renal injury induced by chronic high salt feeding in mice.

Hu J, Luo H, Wang J, Tang W, Lu J, Wu S, Xiong Z, Yang G, Chen Z, Lan T, Zhou H, Nie J, Jiang Y, Chen P
Experimental & molecular medicine 2017 Aug 25;49(8):e370

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Structure-based virtual screening and optimization of modulators targeting Hsp90-Cdc37 interaction.

Wang L, Li L, Zhou ZH, Jiang ZY, You QD, Xu XL
European journal of medicinal chemistry 2017 Aug 18;136:63-73

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Exogenous H(2)S facilitating ubiquitin aggregates clearance via autophagy attenuates type 2 diabetes-induced cardiomyopathy.

Wu J, Tian Z, Sun Y, Lu C, Liu N, Gao Z, Zhang L, Dong S, Yang F, Zhong X, Xu C, Lu F, Zhang W
Cell death & disease 2017 Aug 10;8(8):e2992

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High expression of RBM8A predicts poor patient prognosis and promotes tumor progression in hepatocellular carcinoma.

Liang R, Lin Y, Ye JZ, Yan XX, Liu ZH, Li YQ, Luo XL, Ye HH
Oncology reports 2017 Apr;37(4):2167-2176

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Upregulated unique long 16 binding protein 1 detected in preeclamptic placenta affects human extravillous trophoblast cell line (HTR-8/SVneo) invasion by modulating the function of uterine natural killer cells.

Liu J, Song G, Lin X, Pang X, Meng T
Experimental and therapeutic medicine 2017 Apr;13(4):1447-1455

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Endogenous Stem Cells Were Recruited by Defocused Low-Energy Shock Wave in Treating Diabetic Bladder Dysfunction.

Jin Y, Xu L, Zhao Y, Wang M, Jin X, Zhang H
Stem cell reviews and reports 2017 Apr;13(2):287-298

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Autoinhibition of Dishevelled protein regulated by its extreme C terminus plays a distinct role in Wnt/β-catenin and Wnt/planar cell polarity (PCP) signaling pathways.

Qi J, Lee HJ, Saquet A, Cheng XN, Shao M, Zheng JJ, Shi DL
The Journal of biological chemistry 2017 Apr 7;292(14):5898-5908

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A novel glutaminase inhibitor-968 inhibits the migration and proliferation of non-small cell lung cancer cells by targeting EGFR/ERK signaling pathway.

Han T, Guo M, Zhang T, Gan M, Xie C, Wang JB
Oncotarget 2017 Apr 25;8(17):28063-28073

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Paper/PMMA Hybrid 3D Cell Culture Microfluidic Platform for the Study of Cellular Crosstalk.

Lei KF, Chang CH, Chen MJ
ACS applied materials & interfaces 2017 Apr 19;9(15):13092-13101

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Tenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicity.

Zhao X, Sun K, Lan Z, Song W, Cheng L, Chi W, Chen J, Huo Y, Xu L, Liu X, Deng H, Siegenthaler JA, Chen L
Scientific reports 2017 Apr 11;7:46344

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Discovery of a small molecule targeting ULK1-modulated cell death of triple negative breast cancer in vitro and in vivo.

Zhang L, Fu L, Zhang S, Zhang J, Zhao Y, Zheng Y, He G, Yang S, Ouyang L, Liu B
Chemical science 2017 Apr 1;8(4):2687-2701

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The role of TGF-β-activated kinase 1 in db/db mice and high glucose-induced macrophage.

Xu X, Fan Z, Qi X, Shao Y, Wu Y
International immunopharmacology 2016 Sep;38:120-31

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B7-H4 expression in human infiltrating ductal carcinoma‑associated macrophages.

Liu L, Li D, Chen S, Zhao R, Pang D, Li D, Fu Z
Molecular medicine reports 2016 Sep;14(3):2135-42

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Interleukin-11 promotes epithelial-mesenchymal transition in anaplastic thyroid carcinoma cells through PI3K/Akt/GSK3β signaling pathway activation.

Zhong Z, Hu Z, Jiang Y, Sun R, Chen X, Chu H, Zeng M, Sun C
Oncotarget 2016 Sep 13;7(37):59652-59663

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Functional characterization of hepatitis B virus core promoter mutants revealed transcriptional interference among co-terminal viral mRNAs.

Chen C, Jia H, Zhang F, Qin Y, Zong L, Yuan Q, Wang Y, Xia N, Li J, Wen Y, Tong S
The Journal of general virology 2016 Oct;97(10):2668-2676

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Effect of Polygonatum odoratum extract on human breast cancer MDA-MB-231 cell proliferation and apoptosis.

Tai Y, Sun YM, Zou X, Pan Q, Lan YD, Huo Q, Zhu JW, Guo F, Zheng CQ, Wu CZ, Liu H
Experimental and therapeutic medicine 2016 Oct;12(4):2681-2687

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Afamin promotes glucose metabolism in papillary thyroid carcinoma.

Shen CT, Wei WJ, Qiu ZL, Song HJ, Luo QY
Molecular and cellular endocrinology 2016 Oct 15;434:108-15

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MicroRNA-181b suppresses TAG via target IRS2 and regulating multiple genes in the Hippo pathway.

Chen Z, Shi H, Sun S, Xu H, Cao D, Luo J
Experimental cell research 2016 Oct 15;348(1):66-74

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HSPB1 deficiency sensitizes melanoma cells to hyperthermia induced cell death.

Wang HX, Yang Y, Guo H, Hou DD, Zheng S, Hong YX, Cai YF, Huo W, Qi RQ, Zhang L, Chen HD, Gao XH
Oncotarget 2016 Oct 11;7(41):67449-67462

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A comparison of incidences of bladder neck contracture of 80- versus 180-W GreenLight laser photoselective vaporization of benign prostatic hyperplasia.

Hu B, Song Z, Liu H, Qiao L, Zhao Y, Wang M, Song W, Zhang D, Jin X, Zhang H
Lasers in medical science 2016 Nov;31(8):1573-1581

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Ubiquitin-dependent Turnover of Adenosine Deaminase Acting on RNA 1 (ADAR1) Is Required for Efficient Antiviral Activity of Type I Interferon.

Li L, Qian G, Zuo Y, Yuan Y, Cheng Q, Guo T, Liu J, Liu C, Zhang L, Zheng H
The Journal of biological chemistry 2016 Nov 25;291(48):24974-24985

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A novel transgenic mouse model of lysosomal storage disorder.

Ortiz-Miranda S, Ji R, Jurczyk A, Aryee KE, Mo S, Fletcher T, Shaffer SA, Greiner DL, Bortell R, Gregg RG, Cheng A, Hennings LJ, Rittenhouse AR
American journal of physiology. Gastrointestinal and liver physiology 2016 Nov 1;311(5):G903-G919

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Foxo3b but not Foxo3a activates cyp19a1a in Epinephelus coioides.

Liu Q, Zhang Y, Shi B, Lu H, Zhang L, Zhang W
Journal of molecular endocrinology 2016 May;56(4):337-49

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Valsartan Attenuates KIR2.1 by Downregulating the Th1 Immune Response in Rats Following Myocardial Infarction.

Li X, Hu H, Wang Y, Xue M, Li X, Cheng W, Xuan Y, Yin J, Yang N, Yan S
Journal of cardiovascular pharmacology 2016 Mar;67(3):252-9

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Human epithelial-type ovarian tumour marker beta-2-microglobulin is regulated by the TGF-β signaling pathway.

Sun W, Gui L, Zuo X, Zhang L, Zhou D, Duan X, Ren W, Xu G
Journal of translational medicine 2016 Mar 16;14:75

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AMPK activation protects cells from oxidative stress-induced senescence via autophagic flux restoration and intracellular NAD(+) elevation.

Han X, Tai H, Wang X, Wang Z, Zhou J, Wei X, Ding Y, Gong H, Mo C, Zhang J, Qin J, Ma Y, Huang N, Xiang R, Xiao H
Aging cell 2016 Jun;15(3):416-27

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Pancreatic cancer risk variant in LINC00673 creates a miR-1231 binding site and interferes with PTPN11 degradation.

Zheng J, Huang X, Tan W, Yu D, Du Z, Chang J, Wei L, Han Y, Wang C, Che X, Zhou Y, Miao X, Jiang G, Yu X, Yang X, Cao G, Zuo C, Li Z, Wang C, Cheung ST, Jia Y, Zheng X, Shen H, Wu C, Lin D
Nature genetics 2016 Jul;48(7):747-57

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Deubiquitinase USP2a Sustains Interferons Antiviral Activity by Restricting Ubiquitination of Activated STAT1 in the Nucleus.

Ren Y, Zhao P, Liu J, Yuan Y, Cheng Q, Zuo Y, Qian L, Liu C, Guo T, Zhang L, Wang X, Qian G, Li L, Ge J, Dai J, Xiong S, Zheng H
PLoS pathogens 2016 Jul;12(7):e1005764

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Inhibitor Discovery for the Human GLUT1 from Homology Modeling and Virtual Screening.

Ung PM, Song W, Cheng L, Zhao X, Hu H, Chen L, Schlessinger A
ACS chemical biology 2016 Jul 15;11(7):1908-16

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Homologous recombination-dependent repair of telomeric DSBs in proliferating human cells.

Mao P, Liu J, Zhang Z, Zhang H, Liu H, Gao S, Rong YS, Zhao Y
Nature communications 2016 Jul 11;7:12154

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Competitive Inhibition of Lysine Acetyltransferase 2B by a Small Motif of the Adenoviral Oncoprotein E1A.

Shi S, Liu K, Chen Y, Zhang S, Lin J, Gong C, Jin Q, Yang XJ, Chen R, Ji Z, Han A
The Journal of biological chemistry 2016 Jul 1;291(27):14363-14372

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Blockade of TGF-β-activated kinase 1 prevents advanced glycation end products-induced inflammatory response in macrophages.

Xu X, Qi X, Shao Y, Li Y, Fu X, Feng S, Wu Y
Cytokine 2016 Feb;78:62-8

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The PLC/PKC/Ras/MEK/Kv channel pathway is involved in uncarboxylated osteocalcin-regulated insulin secretion in rats.

Gao J, Bai T, Ren L, Ding Y, Zhong X, Wang H, Guo Y, Li J, Liu Y, Zhang Y
Peptides 2016 Dec;86:72-79

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Nuclear PTEN interferes with binding of Ku70 at double-strand breaks through post-translational poly(ADP-ribosyl)ation.

Guan J, Zhao Q, Mao W
Biochimica et biophysica acta 2016 Dec;1863(12):3106-3115

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Berberine increases adipose triglyceride lipase in 3T3-L1 adipocytes through the AMPK pathway.

Jiang D, Wang D, Zhuang X, Wang Z, Ni Y, Chen S, Sun F
Lipids in health and disease 2016 Dec 9;15(1):214

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Novel Tetrahydropyrido[4,3-d]pyrimidines as Potent Inhibitors of Chaperone Heat Shock Protein 90.

Jiang F, Wang HJ, Jin YH, Zhang Q, Wang ZH, Jia JM, Liu F, Wang L, Bao QC, Li DD, You QD, Xu XL
Journal of medicinal chemistry 2016 Dec 8;59(23):10498-10519

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Senescence: novel insight into DLX3 mutations leading to enhanced bone formation in Tricho-Dento-Osseous syndrome.

Zhao N, Han D, Liu H, Li Y, Wong SW, Cao Z, Xu J, Zhang X, Cai T, Wang Y, Feng H
Scientific reports 2016 Dec 7;6:38680

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H2O2 treatment or serum deprivation induces autophagy and apoptosis in naked mole-rat skin fibroblasts by inhibiting the PI3K/Akt signaling pathway.

Zhao S, Li L, Wang S, Yu C, Xiao B, Lin L, Cong W, Cheng J, Yang W, Sun W, Cui S
Oncotarget 2016 Dec 20;7(51):84839-84850

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Chronic stress and excessive glucocorticoid exposure both lead to altered Neuregulin-1/ErbB signaling in rat myocardium.

Dang R, Guo Y, Zhang L, Chen L, Yang R, Jiang P
Steroids 2016 Aug;112:47-53

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YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression.

Lyons SM, Achorn C, Kedersha NL, Anderson PJ, Ivanov P
Nucleic acids research 2016 Aug 19;44(14):6949-60

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Enhanced SLC34A2 in breast cancer stem cell-like cells induces chemotherapeutic resistance to doxorubicin via SLC34A2-Bmi1-ABCC5 signaling.

Ge G, Zhou C, Ren Y, Tang X, Wang K, Zhang W, Niu L, Zhou Y, Yan Y, He J
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Apr;37(4):5049-62

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Protective effect of melatonin on myenteric neuron damage in experimental colitis in rats.

Shang B, Shi H, Wang X, Guo X, Wang N, Wang Y, Dong L
Fundamental & clinical pharmacology 2016 Apr;30(2):117-27

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Arsenic sulfide, the main component of realgar, a traditional Chinese medicine, induces apoptosis of gastric cancer cells in vitro and in vivo.

Zhang L, Tian W, Kim S, Ding W, Tong Y, Chen S
Drug design, development and therapy 2015;9:79-92

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Cardiac microvascular barrier function mediates the protection of Tongxinluo against myocardial ischemia/reperfusion injury.

Qi K, Li L, Li X, Zhao J, Wang Y, You S, Hu F, Zhang H, Cheng Y, Kang S, Cui H, Duan L, Jin C, Zheng Q, Yang Y
PloS one 2015;10(3):e0119846

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Elevated GAPDH expression is associated with the proliferation and invasion of lung and esophageal squamous cell carcinomas.

Hao L, Zhou X, Liu S, Sun M, Song Y, Du S, Sun B, Guo C, Gong L, Hu J, Guan H, Shao S
Proteomics 2015 Sep;15(17):3087-100

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Gabarapl1 mediates androgen-regulated autophagy in prostate cancer.

Xie CW, Zhou Y, Liu SL, Fang ZY, Su B, Zhang W
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Nov;36(11):8727-33

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Encephalomyocarditis Virus 3C Protease Relieves TRAF Family Member-associated NF-κB Activator (TANK) Inhibitory Effect on TRAF6-mediated NF-κB Signaling through Cleavage of TANK.

Huang L, Liu Q, Zhang L, Zhang Q, Hu L, Li C, Wang S, Li J, Zhang Y, Yu H, Wang Y, Zhong Z, Xiong T, Xia X, Wang X, Yu L, Deng G, Cai X, Cui S, Weng C
The Journal of biological chemistry 2015 Nov 13;290(46):27618-32

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MiR-101 sensitizes human nasopharyngeal carcinoma cells to radiation by targeting stathmin 1.

Sun Q, Liu T, Zhang T, Du S, Xie GX, Lin X, Chen L, Yuan Y
Molecular medicine reports 2015 May;11(5):3330-6

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Formaldehyde exposure induces autophagy in testicular tissues of adult male rats.

Han SP, Zhou DX, Lin P, Qin Z, An L, Zheng LR, Lei L
Environmental toxicology 2015 Mar;30(3):323-31

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Astrocyte elevated gene-1 promotes progression of cervical squamous cell carcinoma by inducing epithelial-mesenchymal transition via Wnt signaling.

Song E, Yu W, Xiong X, Kuang X, Ai Y, Xiong X
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2015 Mar;25(3):345-55

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MiR-200c inhibits autophagy and enhances radiosensitivity in breast cancer cells by targeting UBQLN1.

Sun Q, Liu T, Yuan Y, Guo Z, Xie G, Du S, Lin X, Xu Z, Liu M, Wang W, Yuan Q, Chen L
International journal of cancer 2015 Mar 1;136(5):1003-12

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G-protein coupled receptor 34 activates Erk and phosphatidylinositol 3-kinase/Akt pathways and functions as alternative pathway to mediate p185Bcr-Abl-induced transformation and leukemogenesis.

Zuo B, Li M, Liu Y, Li K, Ma S, Cui M, Qin Y, Zhu H, Pan X, Guo J, Dai Z, Yu W
Leukemia & lymphoma 2015 Jul;56(7):2170-81

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8-p-Hdroxybenzoyl Tovarol Induces Paraptosis Like Cell Death and Protective Autophagy in Human Cervical Cancer HeLa Cells.

Zhang C, Jiang Y, Zhang J, Huang J, Wang J
International journal of molecular sciences 2015 Jul 2;16(7):14979-96

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Annexin A3 as a potential target for immunotherapy of liver cancer stem-like cells.

Pan QZ, Pan K, Wang QJ, Weng DS, Zhao JJ, Zheng HX, Zhang XF, Jiang SS, Lv L, Tang Y, Li YQ, He J, Liu Q, Chen CL, Zhang HX, Xia JC
Stem cells (Dayton, Ohio) 2015 Feb;33(2):354-66

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Inhibition of JNK3 promotes apoptosis induced by BH3 mimetic S1 in chemoresistant human ovarian cancer cells.

Yang X, Xiang X, Xia M, Su J, Wu Y, Shen L, Xu Y, Sun L
Anatomical record (Hoboken, N.J. : 2007) 2015 Feb;298(2):386-95

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Decreased expression of mucin-1 in endometriosis endometrium correlated with progesterone receptor B involved in infertility.

Shen F, Yan C, Liu M, Feng Y, Chen Y
Archives of gynecology and obstetrics 2015 Feb;291(2):439-45

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Tolerance to endoplasmic reticulum stress mediates cisplatin resistance in human ovarian cancer cells by maintaining endoplasmic reticulum and mitochondrial homeostasis.

Xu Y, Wang C, Su J, Xie Q, Ma L, Zeng L, Yu Y, Liu S, Li S, Li Z, Sun L
Oncology reports 2015 Dec;34(6):3051-60

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IFIT5 positively regulates NF-κB signaling through synergizing the recruitment of IκB kinase (IKK) to TGF-β-activated kinase 1 (TAK1).

Zheng C, Zheng Z, Zhang Z, Meng J, Liu Y, Ke X, Hu Q, Wang H
Cellular signalling 2015 Dec;27(12):2343-54

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Mitophagy in APPsw/PS1dE9 transgenic mice and APPsw stably expressing in HEK293 cells.

Wang X, Zhao XL, Xu LL, Wang CF, Wei LF, Liu Z, Yang H, Wang P, Xie ZH, Bi JZ
European review for medical and pharmacological sciences 2015 Dec;19(23):4595-602

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G1/S Cell Cycle Checkpoint Dysfunction in Lymphoblasts from Sporadic Parkinson's Disease Patients.

Esteras N, Alquézar C, Bartolomé F, de la Encarnación A, Bermejo-Pareja F, Molina JA, Martín-Requero Á
Molecular neurobiology 2015 Aug;52(1):386-98

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Lentivirus vector-mediated gene transduction of CNGRC peptide in rat adipose stem cells.

Meng D, Liu R, Pei L, Hou L, Ning Q, Yu Q, Feng L, Zhao X
Molecular medicine reports 2015 Apr;11(4):2555-61

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Directional Plk1 inhibition-driven cell cycle interruption using amphiphilic thin-coated peptide-lanthanide upconversion nanomaterials as in vivo tumor suppressors.

Chan CF, Lan R, Tsang MK, Zhou D, Lear S, Chan WL, Cobb SL, Wong WK, Hao J, Wong WT, Wong KL
Journal of materials chemistry. B 2015 Apr 7;3(13):2624-2634

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Neuropilin-1 promotes epithelial-to-mesenchymal transition by stimulating nuclear factor-kappa B and is associated with poor prognosis in human oral squamous cell carcinoma.

Chu W, Song X, Yang X, Ma L, Zhu J, He M, Wang Z, Wu Y
PloS one 2014;9(7):e101931

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Altered expression of hypoxia-inducible factor-1α (HIF-1α) and its regulatory genes in gastric cancer tissues.

Wang J, Ni Z, Duan Z, Wang G, Li F
PloS one 2014;9(6):e99835

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Proteomics approaches for identification of tumor relevant protein targets in pulmonary squamous cell carcinoma by 2D-DIGE-MS.

Lihong H, Linlin G, Yiping G, Yang S, Xiaoyu Q, Zhuzhu G, Xiaohan Y, Xin Z, Liyan X, Shujuan S
PloS one 2014;9(4):e95121

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The association of HMGB1 gene with the prognosis of HCC.

Xiao J, Ding Y, Huang J, Li Q, Liu Y, Ni W, Zhang Y, Zhu Y, Chen L, Chen B
PloS one 2014;9(2):e89097

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Tetramethylpyrazine ameliorates high glucose-induced endothelial dysfunction by increasing mitochondrial biogenesis.

Xu Q, Xia P, Li X, Wang W, Liu Z, Gao X
PloS one 2014;9(2):e88243

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Prognostic value of myeloid differentiation primary response 88 and Toll-like receptor 4 in breast cancer patients.

Ma FJ, Liu ZB, Hu X, Ling H, Li S, Wu J, Shao ZM
PloS one 2014;9(10):e111639

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Elevated MiR-222-3p promotes proliferation and invasion of endometrial carcinoma via targeting ERα.

Liu B, Che Q, Qiu H, Bao W, Chen X, Lu W, Li B, Wan X
PloS one 2014;9(1):e87563

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Matrix metalloproteinase 3 promotes cellular anti-dengue virus response via interaction with transcription factor NFκB in cell nucleus.

Zuo X, Pan W, Feng T, Shi X, Dai J
PloS one 2014;9(1):e84748

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Cytotoxicity induced by nanobacteria and nanohydroxyapatites in human choriocarcinoma cells.

Zhang M, Yang J, Shu J, Fu C, Liu S, Xu G, Zhang D
Nanoscale research letters 2014;9(1):616

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PNMA1 promotes cell growth in human pancreatic ductal adenocarcinoma.

Jiang SH, He P, Ma MZ, Wang Y, Li RK, Fang F, Fu Y, Tian GA, Qin WX, Zhang ZG
International journal of clinical and experimental pathology 2014;7(7):3827-35

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mTOR inhibitor AZD8055 inhibits proliferation and induces apoptosis in laryngeal carcinoma.

Zhao L, Teng B, Wen L, Feng Q, Wang H, Li N, Wang Y, Liang Z
International journal of clinical and experimental medicine 2014;7(2):337-47

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Involvement of TLR4 in oxidized LDL/β2GPI/anti-β2GPI-induced transformation of macrophages to foam cells.

Zhang X, Xie Y, Zhou H, Xu Y, Liu J, Xie H, Yan J
Journal of atherosclerosis and thrombosis 2014;21(11):1140-51

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Ganoderma lucidum polysaccharides target a Fas/caspase dependent pathway to induce apoptosis in human colon cancer cells.

Liang Z, Guo YT, Yi YJ, Wang RC, Hu QL, Xiong XY
Asian Pacific journal of cancer prevention : APJCP 2014;15(9):3981-6

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Atorvastatin induces autophagy of mesenchymal stem cells under hypoxia and serum deprivation conditions by activating the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway.

Li N, Zhang Q, Qian H, Jin C, Yang Y, Gao R
Chinese medical journal 2014;127(6):1046-51

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Geniposide and its iridoid analogs exhibit antinociception by acting at the spinal GLP-1 receptors.

Gong N, Fan H, Ma AN, Xiao Q, Wang YX
Neuropharmacology 2014 Sep;84:31-45

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Cryopreserved mouse fetal liver stromal cells treated with mitomycin C are able to support the growth of human embryonic stem cells.

Zhang W, Hu J, Ma Q, Hu S, Wang Y, Wen X, Ma Y, Xu H, Qian H, Xu W
Experimental and therapeutic medicine 2014 Sep;8(3):935-942

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USP33, a new player in lung cancer, mediates Slit-Robo signaling.

Wen P, Kong R, Liu J, Zhu L, Chen X, Li X, Nie Y, Wu K, Wu JY
Protein & cell 2014 Sep;5(9):704-13

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Neuroprotective role of BNIP3 under oxidative stress through autophagy in neuroblastoma cells.

Awan MU, Hasan M, Iqbal J, Lei R, Lee WF, Hong M, Qing H, Deng Y
Molecular biology reports 2014 Sep;41(9):5729-34

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Dysregulation of vitamin D metabolism in the brain and myocardium of rats following prolonged exposure to dexamethasone.

Jiang P, Xue Y, Li HD, Liu YP, Cai HL, Tang MM, Zhang LH
Psychopharmacology 2014 Sep;231(17):3445-51

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In vitro and in vivo protection against enterovirus 71 by an antisense phosphorothioate oligonucleotide.

Liu J, Zhou Z, Li K, Han M, Yang J, Wang S
Archives of virology 2014 Sep;159(9):2339-47

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Lipoxin A4 methyl ester ameliorates cognitive deficits induced by chronic cerebral hypoperfusion through activating ERK/Nrf2 signaling pathway in rats.

Jin W, Jia Y, Huang L, Wang T, Wang H, Dong Y, Zhang H, Fan M, Lv P
Pharmacology, biochemistry, and behavior 2014 Sep;124:145-52

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Direct interaction of 14-3-3ζ with ezrin promotes cell migration by regulating the formation of membrane ruffle.

Chen M, Liu T, Xu L, Gao X, Liu X, Wang C, He Q, Zhang G, Liu L
Journal of molecular biology 2014 Sep 9;426(18):3118-3133

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Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology.

Orosco LA, Ross AP, Cates SL, Scott SE, Wu D, Sohn J, Pleasure D, Pleasure SJ, Adamopoulos IE, Zarbalis KS
Nature communications 2014 Sep 8;5:4692

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Bone marrow mesenchymal stem cells repair spinal cord ischemia/reperfusion injury by promoting axonal growth and anti-autophagy.

Yin F, Meng C, Lu R, Li L, Zhang Y, Chen H, Qin Y, Guo L
Neural regeneration research 2014 Sep 15;9(18):1665-71

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A central role for TRPS1 in the control of cell cycle and cancer development.

Wu L, Wang Y, Liu Y, Yu S, Xie H, Shi X, Qin S, Ma F, Tan TZ, Thiery JP, Chen L
Oncotarget 2014 Sep 15;5(17):7677-90

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Cationic poly(amidoamine) dendrimers induced cyto-protective autophagy in hepatocellular carcinoma cells.

Li Y, Wang S, Wang Z, Qian X, Fan J, Zeng X, Sun Y, Song P, Feng M, Ju D
Nanotechnology 2014 Sep 12;25(36):365101

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Ezrin is required for epithelial-mesenchymal transition induced by TGF-β1 in A549 cells.

Chen MJ, Gao XJ, Xu LN, Liu TF, Liu XH, Liu LX
International journal of oncology 2014 Oct;45(4):1515-22

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Novel microRNA-like viral small regulatory RNAs arising during human hepatitis A virus infection.

Shi J, Sun J, Wang B, Wu M, Zhang J, Duan Z, Wang H, Hu N, Hu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2014 Oct;28(10):4381-93

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Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.

Xu D, Hu L, Su C, Xia X, Zhang P, Fu J, Wang W, Xu D, Du H, Hu Q, Song E, Song Y
Toxicology and applied pharmacology 2014 Oct 15;280(2):305-13

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Chronic stress causes neuroendocrine-immune disturbances without affecting renal vitamin D metabolism in rats.

Jiang P, Zhang L, Zhu W, Li H, Dang R, Tang M
Journal of endocrinological investigation 2014 Nov;37(11):1109-16

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MicroRNA-145 inhibits cell proliferation by directly targeting ADAM17 in hepatocellular carcinoma.

Liu Y, Wu C, Wang Y, Wen S, Wang J, Chen Z, He Q, Feng D
Oncology reports 2014 Nov;32(5):1923-30

---

Toxic effects of levofloxacin on rat annulus fibrosus cells: an in-vitro study.

Bai ZL, Chen Q, Yang SD, Zhang F, Wang HY, Yang DL, Ding WY
Medical science monitor : international medical journal of experimental and clinical research 2014 Nov 8;20:2205-12

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Cholesterol-conjugated let-7a mimics: antitumor efficacy on hepatocellular carcinoma in vitro and in a preclinical orthotopic xenograft model of systemic therapy.

Liu YM, Xia Y, Dai W, Han HY, Dong YX, Cai J, Zeng X, Luo FY, Yang T, Li YZ, Chen J, Guan J
BMC cancer 2014 Nov 28;14:889

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Phosphatidylinositol 3-kinase CB association with preoperative radiotherapy response in rectal adenocarcinoma.

Yu WD, Peng YF, Pan HD, Wang L, Li K, Gu J
World journal of gastroenterology 2014 Nov 21;20(43):16258-67

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Levels of human replication factor C4, a clamp loader, correlate with tumor progression and predict the prognosis for colorectal cancer.

Xiang J, Fang L, Luo Y, Yang Z, Liao Y, Cui J, Huang M, Yang Z, Huang Y, Fan X, Wang H, Wang L, Peng J, Wang J
Journal of translational medicine 2014 Nov 19;12:320

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Curcumin improves the integrity of blood-spinal cord barrier after compressive spinal cord injury in rats.

Yu DS, Cao Y, Mei XF, Wang YF, Fan ZK, Wang YS, Lv G
Journal of the neurological sciences 2014 Nov 15;346(1-2):51-9

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The sodium channel β1 subunit mediates outgrowth of neurite-like processes on breast cancer cells and promotes tumour growth and metastasis.

Nelson M, Millican-Slater R, Forrest LC, Brackenbury WJ
International journal of cancer 2014 Nov 15;135(10):2338-51

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17β-Estradiol protects against apoptosis induced by levofloxacin in rat nucleus pulposus cells by upregulating integrin α2β1.

Yang SD, Ma L, Gu TX, Ding WY, Zhang F, Shen Y, Zhang YZ, Yang DL, Zhang D, Sun YP, Song YL
Apoptosis : an international journal on programmed cell death 2014 May;19(5):789-800

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Nitro-oleic acid downregulates lipoprotein-associated phospholipase A2 expression via the p42/p44 MAPK and NFκB pathways.

Wang G, Ji Y, Li Z, Han X, Guo N, Song Q, Quan L, Wang T, Han W, Pang D, Ouyang H, Tang X
Scientific reports 2014 May 9;4:4905

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Microcystin-LR stabilizes c-myc protein by inhibiting protein phosphatase 2A in HEK293 cells.

Fan H, Cai Y, Xie P, Xiao W, Chen J, Ji W, Zhao S
Toxicology 2014 May 7;319:69-74

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Chemical characterization and antitumor activities of polysaccharide extracted from Ganoderma lucidum.

Liang Z, Yi Y, Guo Y, Wang R, Hu Q, Xiong X
International journal of molecular sciences 2014 May 22;15(5):9103-16

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A caspase-dependent pathway is involved in Wnt/β-catenin signaling promoted apoptosis in Bacillus Calmette-Guerin infected RAW264.7 macrophages.

Wu X, Deng G, Hao X, Li Y, Zeng J, Ma C, He Y, Liu X, Wang Y
International journal of molecular sciences 2014 Mar 21;15(3):5045-62

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HMG-CoA reductase is negatively associated with PCV2 infection and PCV2-induced apoptotic cell death.

Yang X, Ouyang H, Chen F, Pang D, Dong M, Yang S, Liu X, Peng Z, Wang F, Zhang X, Ren L
The Journal of general virology 2014 Jun;95(Pt 6):1330-1337

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Downregulation of p16(ink4a) inhibits cell proliferation and induces G1 cell cycle arrest in cervical cancer cells.

Zhang CY, Bao W, Wang LH
International journal of molecular medicine 2014 Jun;33(6):1577-85

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Zebrafish Cacna1fa is required for cone photoreceptor function and synaptic ribbon formation.

Jia S, Muto A, Orisme W, Henson HE, Parupalli C, Ju B, Baier H, Taylor MR
Human molecular genetics 2014 Jun 1;23(11):2981-94

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TNF-α promotes early atherosclerosis by increasing transcytosis of LDL across endothelial cells: crosstalk between NF-κB and PPAR-γ.

Zhang Y, Yang X, Bian F, Wu P, Xing S, Xu G, Li W, Chi J, Ouyang C, Zheng T, Wu D, Zhang Y, Li Y, Jin S
Journal of molecular and cellular cardiology 2014 Jul;72:85-94

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Effects of natural mineral-rich water consumption on the expression of sirtuin 1 and angiogenic factors in the erectile tissue of rats with fructose-induced metabolic syndrome.

Pereira CD, Severo M, Rafael L, Martins MJ, Neves D
Asian journal of andrology 2014 Jul-Aug;16(4):631-8

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Ruthenium(II) polypyridyl complexes: cellular uptake, cell image and apoptosis of HeLa cancer cells induced by double targets.

Yu Q, Liu Y, Xu L, Zheng C, Le F, Qin X, Liu Y, Liu J
European journal of medicinal chemistry 2014 Jul 23;82:82-95

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Lactobacillus casei reduces susceptibility to type 2 diabetes via microbiota-mediated body chloride ion influx.

Zhang Y, Guo X, Guo J, He Q, Li H, Song Y, Zhang H
Scientific reports 2014 Jul 18;4:5654

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Nanoscale chromatin profiling of gastric adenocarcinoma reveals cancer-associated cryptic promoters and somatically acquired regulatory elements.

Muratani M, Deng N, Ooi WF, Lin SJ, Xing M, Xu C, Qamra A, Tay ST, Malik S, Wu J, Lee MH, Zhang S, Tan LL, Chua H, Wong WK, Ong HS, Ooi LL, Chow PK, Chan WH, Soo KC, Goh LK, Rozen S, Teh BT, Yu Q, Ng HH, Tan P
Nature communications 2014 Jul 10;5:4361

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Chondroprotective effects and multi-target mechanisms of Icariin in IL-1 beta-induced human SW 1353 chondrosarcoma cells and a rat osteoarthritis model.

Zeng L, Wang W, Rong XF, Zhong Y, Jia P, Zhou GQ, Li RH
International immunopharmacology 2014 Jan;18(1):175-81

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Protection of ischemic post conditioning against transient focal ischemia-induced brain damage is associated with inhibition of neuroinflammation via modulation of TLR2 and TLR4 pathways.

Wang Y, Ge P, Yang L, Wu C, Zha H, Luo T, Zhu Y
Journal of neuroinflammation 2014 Jan 24;11:15

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Expression of SPRR3 is associated with tumor cell proliferation and invasion in glioblastoma multiforme.

Liu Q, Zhang C, Ma G, Zhang Q
Oncology letters 2014 Feb;7(2):427-432

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MiR-451 increases radiosensitivity of nasopharyngeal carcinoma cells by targeting ras-related protein 14 (RAB14).

Zhang T, Sun Q, Liu T, Chen J, Du S, Ren C, Liao G, Yuan Y
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2014 Dec;35(12):12593-9

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Fluoride affects calcium homeostasis and osteogenic transcription factor expressions through L-type calcium channels in osteoblast cell line.

Duan XQ, Zhao ZT, Zhang XY, Wang Y, Wang H, Liu DW, Li GS, Jing L
Biological trace element research 2014 Dec;162(1-3):219-26

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MicroRNA-15b promotes neurogenesis and inhibits neural progenitor proliferation by directly repressing TET3 during early neocortical development.

Lv X, Jiang H, Liu Y, Lei X, Jiao J
EMBO reports 2014 Dec;15(12):1305-14

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Lentiviral vector-mediated RBM5 overexpression downregulates EGFR expression in human non-small cell lung cancer cells.

Su Z, Yin J, Zhao L, Li R, Liang H, Zhang J, Wang K
World journal of surgical oncology 2014 Dec 2;12:367

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Blocking autophagy enhanced cytotoxicity induced by recombinant human arginase in triple-negative breast cancer cells.

Wang Z, Shi X, Li Y, Fan J, Zeng X, Xian Z, Wang Z, Sun Y, Wang S, Song P, Zhao S, Hu H, Ju D
Cell death & disease 2014 Dec 11;5(12):e1563

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The expression level of TRAF1 in human gastric mucosa is related to virulence genotypes of Helicobacter pylori.

Wang F, Bu G, Feng Q, Liu Z, Xu C, Shen S, Yuan Y
Scandinavian journal of gastroenterology 2014 Aug;49(8):925-32

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Reversal of multidrug resistance in vitro and in vivo by 5-N-formylardeemin, a new ardeemin derivative.

Zheng X, Li D, Zhao C, Wang Q, Song H, Qin Y, Liao L, Zhang L, Lin Y, Wang X
Apoptosis : an international journal on programmed cell death 2014 Aug;19(8):1293-300

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oxLDL/β2GPI/anti-β2GPI complex induced macrophage differentiation to foam cell involving TLR4/NF-kappa B signal transduction pathway.

Xu Y, Kong X, Zhou H, Zhang X, Liu J, Yan J, Xie H, Xie Y
Thrombosis research 2014 Aug;134(2):384-92

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Anthocyanin-rich fractions from red raspberries attenuate inflammation in both RAW264.7 macrophages and a mouse model of colitis.

Li L, Wang L, Wu Z, Yao L, Wu Y, Huang L, Liu K, Zhou X, Gou D
Scientific reports 2014 Aug 29;4:6234

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The crucial role of Atg5 in cortical neurogenesis during early brain development.

Lv X, Jiang H, Li B, Liang Q, Wang S, Zhao Q, Jiao J
Scientific reports 2014 Aug 11;4:6010

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si-DNMT1 restore tumor suppressor genes expression through the reversal of DNA hypermethylation in cholangiocarcinoma.

Xiang J, Luo F, Chen Y, Zhu F, Wang J
Clinics and research in hepatology and gastroenterology 2014 Apr;38(2):181-9

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NLRP3 deficiency ameliorates neurovascular damage in experimental ischemic stroke.

Yang F, Wang Z, Wei X, Han H, Meng X, Zhang Y, Shi W, Li F, Xin T, Pang Q, Yi F
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2014 Apr;34(4):660-7

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A synergic role of caspase-6 and caspase-3 in Tau truncation at D421 induced by H2O 2.

Zhao H, Zhao W, Lok K, Wang Z, Yin M
Cellular and molecular neurobiology 2014 Apr;34(3):369-78

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miR-200c inhibits metastasis of breast cancer cells by targeting HMGB1.

Chang BP, Wang DS, Xing JW, Yang SH, Chu Q, Yu SY
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2014 Apr;34(2):201-206

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Epigallocatechin-3-gallate inhibits TF and TNF-α expression induced by the anti-β2GPI/β2GPI complex in human THP-1 cells.

Wang T, Zhou H, Xie H, Mu Y, Xu Y, Liu J, Zhang X
International journal of molecular medicine 2014 Apr;33(4):994-1002

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Association analysis of UGT1A genotype and haplotype with SN-38 glucuronidation in human livers.

Wang H, Bian T, Jin T, Chen Y, Lin A, Chen C
Pharmacogenomics 2014 Apr;15(6):785-98

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Activation of spinal glucagon-like peptide-1 receptors specifically suppresses pain hypersensitivity.

Gong N, Xiao Q, Zhu B, Zhang CY, Wang YC, Fan H, Ma AN, Wang YX
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Apr 9;34(15):5322-34

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Ezh2 regulates adult hippocampal neurogenesis and memory.

Zhang J, Ji F, Liu Y, Lei X, Li H, Ji G, Yuan Z, Jiao J
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Apr 9;34(15):5184-99

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Ubiquitin B in cervical cancer: critical for the maintenance of cancer stem-like cell characters.

Tian Y, Ding W, Wang Y, Ji T, Sun S, Mo Q, Chen P, Fang Y, Liu J, Wang B, Zhou J, Ma D, Wu P
PloS one 2013;8(12):e84457

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Simvastatin alleviates hyperpermeability of glomerular endothelial cells in early-stage diabetic nephropathy by inhibition of RhoA/ROCK1.

Peng H, Luo P, Li Y, Wang C, Liu X, Ye Z, Li C, Lou T
PloS one 2013;8(11):e80009

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NOD2 deficiency protects against cardiac remodeling after myocardial infarction in mice.

Li X, Li F, Chu Y, Wang X, Zhang H, Hu Y, Zhang Y, Wang Z, Wei X, Jian W, Zhang X, Yi F
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2013;32(6):1857-66

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Scutellarin attenuates hypertension-induced expression of brain Toll-like receptor 4/nuclear factor kappa B.

Chen X, Shi X, Zhang X, Lei H, Long S, Su H, Pei Z, Huang R
Mediators of inflammation 2013;2013:432623

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Anti-β2GPI/β2GPI stimulates activation of THP-1 cells through TLR4/MD-2/MyD88 and NF-κB signaling pathways.

Zhou H, Sheng L, Wang H, Xie H, Mu Y, Wang T, Yan J
Thrombosis research 2013;132(6):742-9

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Overexpression of 4EBP1, p70S6K, Akt1 or Akt2 differentially promotes Coxsackievirus B3-induced apoptosis in HeLa cells.

Li X, Li Z, Zhou W, Xing X, Huang L, Tian L, Chen J, Chen C, Ma X, Yang Z
Cell death & disease 2013 Sep 12;4(9):e803-9

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L-3-n-butylphthalide protects against vascular dementia via activation of the Akt kinase pathway.

Huai Y, Dong Y, Xu J, Meng N, Song C, Li W, Lv P
Neural regeneration research 2013 Jul 5;8(19):1733-42

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Specific deletion of Cdc42 does not affect meiotic spindle organization/migration and homologous chromosome segregation but disrupts polarity establishment and cytokinesis in mouse oocytes.

Wang ZB, Jiang ZZ, Zhang QH, Hu MW, Huang L, Ou XH, Guo L, Ouyang YC, Hou Y, Brakebusch C, Schatten H, Sun QY
Molecular biology of the cell 2013 Dec;24(24):3832-41

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Nucleoside analog inhibits microRNA-214 through targeting heat-shock factor 1 in human epithelial ovarian cancer.

Chen YF, Dong Z, Xia Y, Tang J, Peng L, Wang S, Lai D
Cancer science 2013 Dec;104(12):1683-9

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Astragaloside IV attenuates inflammatory cytokines by inhibiting TLR4/NF-кB signaling pathway in isoproterenol-induced myocardial hypertrophy.

Yang J, Wang HX, Zhang YJ, Yang YH, Lu ML, Zhang J, Li ST, Zhang SP, Li G
Journal of ethnopharmacology 2013 Dec 12;150(3):1062-70

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Identification and analysis of glycogen synthase kinase 3 beta1 interactome.

Gao X, Wang JY, Gao LM, Yin XF, Liu L
Cell biology international 2013 Aug;37(8):768-79

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Concurrent blockade of NF-κB and Akt pathways potentiates cisplatin's antitumor activity in vivo.

Sun H, Zheng X, Wang Q, Yan J, Li D, Zhou Y, Lin Y, Zhang L, Wang X
Anti-cancer drugs 2012 Nov;23(10):1039-46

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Anti-inflammatory mechanism of taurine against ischemic stroke is related to down-regulation of PARP and NF-κB.

Sun M, Zhao Y, Gu Y, Xu C
Amino acids 2012 May;42(5):1735-47

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Surgery upregulates high mobility group box-1 and disrupts the blood-brain barrier causing cognitive dysfunction in aged rats.

He HJ, Wang Y, Le Y, Duan KM, Yan XB, Liao Q, Liao Y, Tong JB, Terrando N, Ouyang W
CNS neuroscience & therapeutics 2012 Dec;18(12):994-1002

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Regulation of fibroblast growth factor-2 expression and cell cycle progression by an endogenous antisense RNA.

Baguma-Nibasheka M, Macfarlane LA, Murphy PR
Genes 2012 Aug 16;3(3):505-20

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Rosuvastatin treatment activates JAK-STAT pathway and increases efficacy of allogeneic mesenchymal stem cell transplantation in infarcted hearts.

Xu H, Yang YJ, Qian HY, Tang YD, Wang H, Zhang Q
Circulation journal : official journal of the Japanese Circulation Society 2011;75(6):1476-85

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Involvement of IRAKs and TRAFs in anti-β₂GPI/β₂GPI-induced tissue factor expression in THP-1 cells.

Xu G, Wen H, Zhou H, Guo D, Zhou F, Chen D, Xie H, Wang T, Wang H
Thrombosis and haemostasis 2011 Dec;106(6):1158-69

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Atorvastatin prevents mesenchymal stem cells from hypoxia and serum-free injury through activating AMP-activated protein kinase.

Dong Q, Yang Y, Song L, Qian H, Xu Z
International journal of cardiology 2011 Dec 15;153(3):311-6

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Lentiviral-mediated siRNA targeted against osteopontin suppresses the growth and metastasis of gastric cancer cells.

Wang ZM, Cui YH, Li W, Chen SY, Liu TS
Oncology reports 2011 Apr;25(4):997-1003

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Perturbation of survivin expression affects chromosome alignment and spindle checkpoint in mouse oocyte meiotic maturation.

Sun SC, Wei L, Li M, Lin SL, Xu BZ, Liang XW, Kim NH, Schatten H, Lu SS, Sun QY
Cell cycle (Georgetown, Tex.) 2009 Oct 15;8(20):3365-72

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[Effects of paclitaxel and gefitinib on the proliferation and cell cycle of human lung adenocarcinoma cell SPC-A1.].

Jia G, Zhang W, Zhou J, Zhu Z
Zhongguo fei ai za zhi = Chinese journal of lung cancer 2008 Jun 20;11(3):339-44

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

The beta actin antibody from Proteintech is a mouse monoclonal antibody to a fusion protein of human beta actin. This antibody recognizes human,monkey,mouse,rat,hamster,zebra fish antigen. The beta actin antibody has been validated for the following applications: ELISA, IHC, IF, IP, WB analysis.

Appendix

66009-1-Ig.pdf

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Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunofluorescent analysis of HepG2 cells, using ACTB antibody 66009-1-lg at 1:200 dilution and Rhodamine-labeled goat anti-mouse IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).

Sample type

cell line

Immunoprecipitation

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

IP Result of anti-beta actin (IP:66009-1-Ig, 3ug; Detection:66009-1-Ig 1:10000) with HeLa cells lysate 3100ug.

Sample type

cell line

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human kidney using 66009-1-Ig(Actin antibody) at dilution of 1:500 (under 40x lens)

Sample type

tissue