orb386040

antibody from Biorbyt

Targeting: CLTB Lcb

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

orb386040

Provider

Biorbyt

Product name

Clatherin Light Chain Antibody (LCA/LCB)

Antibody type

Monoclonal

Description

Recognizes proteins of 31-44kDa, which are identified as Clathrin Light Chains (both A & B). Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin light chain regulates the self-assembly of triskelions onto intracellular membranes. Clathrin light chain subunits (LCA and LCB) contribute to regulation of coated vesicle formation to sort proteins during receptor-mediated endocytosis and organelle biogenesis. LCA and LCB are encoded by two discrete genes. They share only 60% homology, and have certain features in common. Both LCA and LCB undergo alternative mRNA splicing, which results in the generation of tissue-specific isoforms.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Antibody clone number

CLC/1421

Vial size

20 ug

Storage

Store the Clathrin Light Chain antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).