Antibody data
- Antibody Data
- Antigen structure
- References [24]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 13427-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13427-1-AP, RRID:AB_2082477
- Product name
- CNPase antibody
- Antibody type
- Polyclonal
- Description
- CNPase antibody (Cat. #13427-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references VSNL1 attenuates hypoxia‑induced myocardial apoptosis by regulating the CNP/NPRB pathway.
Sodium Alginate Attenuates H(2)O(2)-Induced Myocardial DNA Damage via VSNL1 Regulating the CNP/NPR-B Signaling Pathway.
Gastrodin reduces myocardial ischemia/reperfusion injury via transgelin2/CNPase-mediated apoptosis regulation.
Novel "hot spring"-mimetic scaffolds for sequential neurovascular network reconstruction and osteoporosis reversion.
Glycyrrhizin Attenuates White Matter Injury by Inhibiting Neuroinflammation through the HMGB1/TLR4 Pathway.
Combined enriched environment and fluoxetine enhance myelin protein expression in the prefrontal cortex of a chronic unpredictable stress depression model.
FGF21 Alleviates Hypoxic-Ischemic White Matter Injury in Neonatal Mice by Mediating Inflammation and Oxidative Stress Through PPAR-γ Signaling Pathway.
The Neuroprotective Mechanisms of PPAR-γ: Inhibition of Microglia-Mediated Neuroinflammation and Oxidative Stress in a Neonatal Mouse Model of Hypoxic-Ischemic White Matter Injury.
Circadian misalignment impairs oligodendrocyte myelination via Bmal1 overexpression leading to anxiety and depression-like behaviors.
A High MCT-Based Ketogenic Diet Suppresses Th1 and Th17 Responses to Ameliorate Experimental Autoimmune Encephalomyelitis in Mice by Inhibiting GSDMD and JAK2-STAT3/4 Pathways.
Prednisolone improves hippocampal regeneration after trimethyltin-induced neurodegeneration in association with prevention of T lymphocyte infiltration.
L-ascorbyl-2-phosphate alleviates white matter injury caused by chronic hypoxia through the PRMT5/P53/NF-κB pathway.
Phenylalanine-tRNA aminoacylation is compromised by ALS/FTD-associated C9orf72 C4G2 repeat RNA.
T0901317, a liver X receptor agonist, ameliorates perinatal white matter injury induced by ischemia and hypoxia in neonatal rats.
TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration.
Sodium selenite promotes neurological function recovery after spinal cord injury by inhibiting ferroptosis.
Sec13 promotes oligodendrocyte differentiation and myelin repair through autocrine pleiotrophin signaling.
Neural Stem Cells Overexpressing Nerve Growth Factor Improve Functional Recovery in Rats Following Spinal Cord Injury via Modulating Microenvironment and Enhancing Endogenous Neurogenesis.
Leucoencephalopathy with Pigmented Glia in a Horse with Recurrent Convulsive Seizures.
Transfer of α-synuclein from neurons to oligodendrocytes triggers myelin sheath destruction in methamphetamine administration mice.
Cuprizone-Induced Demyelination in Mouse Hippocampus Is Alleviated by Ketogenic Diet.
Profiling analysis reveals the potential contribution of long non-coding RNAs to preterm white matter injury.
Mechanisms underlying the promotion of functional recovery by deferoxamine after spinal cord injury in rats.
2',3'-cyclic nucleotide 3'-phosphodiesterases inhibit hepatitis B virus replication.
Yang X, Fang W, Chang R, Ma L, Chen X, Li Y
Molecular medicine reports 2026 May;33(5)
Molecular medicine reports 2026 May;33(5)
Sodium Alginate Attenuates H(2)O(2)-Induced Myocardial DNA Damage via VSNL1 Regulating the CNP/NPR-B Signaling Pathway.
Chang R, Fang W, Yang X, Jin J, Han X, Ma L, Li Y, Chen X
Molecular biotechnology 2026 Feb;68(2):435-445
Molecular biotechnology 2026 Feb;68(2):435-445
Gastrodin reduces myocardial ischemia/reperfusion injury via transgelin2/CNPase-mediated apoptosis regulation.
Li C, Rao P, Liu X, Yang L, Jiang Y, Yin G, Li S, Yang P, Sun L
Frontiers in pharmacology 2025;16:1604408
Frontiers in pharmacology 2025;16:1604408
Novel "hot spring"-mimetic scaffolds for sequential neurovascular network reconstruction and osteoporosis reversion.
Zhao Y, Liu J, Hu L, Yao X, Tu R, Goto T, Zhang L, Wu X, Liu G, Dai H
Biomaterials 2025 Sep;320:123191
Biomaterials 2025 Sep;320:123191
Glycyrrhizin Attenuates White Matter Injury by Inhibiting Neuroinflammation through the HMGB1/TLR4 Pathway.
Lou J, Ding B, Fang M, Xie W, Wang X, Wang X, Guo X, Zhu J
Molecular neurobiology 2025 May;62(5):6070-6087
Molecular neurobiology 2025 May;62(5):6070-6087
Combined enriched environment and fluoxetine enhance myelin protein expression in the prefrontal cortex of a chronic unpredictable stress depression model.
Gu J, Liu C, Li Y, Feng L, Geng M, Dong J, Han J, Zhao L, Shao Q, Wang HY, Wang CH
Behavioral and brain functions : BBF 2025 Jun 11;21(1):16
Behavioral and brain functions : BBF 2025 Jun 11;21(1):16
FGF21 Alleviates Hypoxic-Ischemic White Matter Injury in Neonatal Mice by Mediating Inflammation and Oxidative Stress Through PPAR-γ Signaling Pathway.
Fang M, Lu L, Lou J, Ou J, Yu Q, Tao X, Zhu J, Lin Z
Molecular neurobiology 2025 Apr;62(4):4743-4768
Molecular neurobiology 2025 Apr;62(4):4743-4768
The Neuroprotective Mechanisms of PPAR-γ: Inhibition of Microglia-Mediated Neuroinflammation and Oxidative Stress in a Neonatal Mouse Model of Hypoxic-Ischemic White Matter Injury.
Fang M, Yu Q, Ou J, Lou J, Zhu J, Lin Z
CNS neuroscience & therapeutics 2024 Nov;30(11):e70081
CNS neuroscience & therapeutics 2024 Nov;30(11):e70081
Circadian misalignment impairs oligodendrocyte myelination via Bmal1 overexpression leading to anxiety and depression-like behaviors.
Zuo Y, Hou Y, Wang Y, Yuan L, Cheng L, Zhang T
Journal of pineal research 2024 Jan;76(1):e12935
Journal of pineal research 2024 Jan;76(1):e12935
A High MCT-Based Ketogenic Diet Suppresses Th1 and Th17 Responses to Ameliorate Experimental Autoimmune Encephalomyelitis in Mice by Inhibiting GSDMD and JAK2-STAT3/4 Pathways.
Zhang Q, Sun W, Wang Q, Zheng X, Zhang R, Zhang N
Molecular nutrition & food research 2024 Feb;68(3):e2300602
Molecular nutrition & food research 2024 Feb;68(3):e2300602
Prednisolone improves hippocampal regeneration after trimethyltin-induced neurodegeneration in association with prevention of T lymphocyte infiltration.
Sakurai M, Takenaka M, Mitsui Y, Sakai Y, Morimoto M
Neuropathology : official journal of the Japanese Society of Neuropathology 2024 Feb;44(1):21-30
Neuropathology : official journal of the Japanese Society of Neuropathology 2024 Feb;44(1):21-30
L-ascorbyl-2-phosphate alleviates white matter injury caused by chronic hypoxia through the PRMT5/P53/NF-κB pathway.
Ding B, Lou J, Qin T, Xie W, Li D, Li P, Wang X, Lin Z, Guo X, Zhu J
Journal of neurochemistry 2024 Feb;168(2):142-160
Journal of neurochemistry 2024 Feb;168(2):142-160
Phenylalanine-tRNA aminoacylation is compromised by ALS/FTD-associated C9orf72 C4G2 repeat RNA.
Malnar Črnigoj M, Čerček U, Yin X, Ho MT, Repic Lampret B, Neumann M, Hermann A, Rouleau G, Suter B, Mayr M, Rogelj B
Nature communications 2023 Sep 16;14(1):5764
Nature communications 2023 Sep 16;14(1):5764
T0901317, a liver X receptor agonist, ameliorates perinatal white matter injury induced by ischemia and hypoxia in neonatal rats.
Gao T, Qian T, Wang T, Su Y, Qiu H, Tang W, Xing Q, Wang L
Neuroscience letters 2023 Jan 10;793:136994
Neuroscience letters 2023 Jan 10;793:136994
TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration.
Xie M, Liu YU, Zhao S, Zhang L, Bosco DB, Pang YP, Zhong J, Sheth U, Martens YA, Zhao N, Liu CC, Zhuang Y, Wang L, Dickson DW, Mattson MP, Bu G, Wu LJ
Nature neuroscience 2022 Jan;25(1):26-38
Nature neuroscience 2022 Jan;25(1):26-38
Sodium selenite promotes neurological function recovery after spinal cord injury by inhibiting ferroptosis.
Chen YX, Zuliyaer T, Liu B, Guo S, Yang DG, Gao F, Yu Y, Yang ML, Du LJ, Li JJ
Neural regeneration research 2022 Dec;17(12):2702-2709
Neural regeneration research 2022 Dec;17(12):2702-2709
Sec13 promotes oligodendrocyte differentiation and myelin repair through autocrine pleiotrophin signaling.
Liu Z, Yan M, Lei W, Jiang R, Dai W, Chen J, Wang C, Li L, Wu M, Nian X, Li D, Sun D, Lv X, Wang C, Xie C, Yao L, Wu C, Hu J, Xiao N, Mo W, Wang Z, Zhang L
The Journal of clinical investigation 2022 Apr 1;132(7)
The Journal of clinical investigation 2022 Apr 1;132(7)
Neural Stem Cells Overexpressing Nerve Growth Factor Improve Functional Recovery in Rats Following Spinal Cord Injury via Modulating Microenvironment and Enhancing Endogenous Neurogenesis.
Wang L, Gu S, Gan J, Tian Y, Zhang F, Zhao H, Lei D
Frontiers in cellular neuroscience 2021;15:773375
Frontiers in cellular neuroscience 2021;15:773375
Leucoencephalopathy with Pigmented Glia in a Horse with Recurrent Convulsive Seizures.
Sakurai M, Isshiki S, Sasaki N, Sakai Y, Yamada Y, Morimoto M
Journal of comparative pathology 2021 Nov;189:120-124
Journal of comparative pathology 2021 Nov;189:120-124
Transfer of α-synuclein from neurons to oligodendrocytes triggers myelin sheath destruction in methamphetamine administration mice.
Ding J, Huang J, Xia B, Hu S, Fan H, Dai J, Li Z, Wang J, Le C, Qiu P, Wang Y
Toxicology letters 2021 Nov 1;352:34-45
Toxicology letters 2021 Nov 1;352:34-45
Cuprizone-Induced Demyelination in Mouse Hippocampus Is Alleviated by Ketogenic Diet.
Liu C, Zhang N, Zhang R, Jin L, Petridis AK, Loers G, Zheng X, Wang Z, Siebert HC
Journal of agricultural and food chemistry 2020 Oct 7;68(40):11215-11228
Journal of agricultural and food chemistry 2020 Oct 7;68(40):11215-11228
Profiling analysis reveals the potential contribution of long non-coding RNAs to preterm white matter injury.
Wang D, Ye X, Xie H, Liu Y, Xu Y, Wang Y, Zhou Y, Zhou N, Wang J
Life sciences 2020 Aug 15;255:117815
Life sciences 2020 Aug 15;255:117815
Mechanisms underlying the promotion of functional recovery by deferoxamine after spinal cord injury in rats.
Hao J, Li B, Duan HQ, Zhao CX, Zhang Y, Sun C, Pan B, Liu C, Kong XH, Yao X, Feng SQ
Neural regeneration research 2017 Jun;12(6):959-968
Neural regeneration research 2017 Jun;12(6):959-968
2',3'-cyclic nucleotide 3'-phosphodiesterases inhibit hepatitis B virus replication.
Ma H, Zhao XL, Wang XY, Xie XW, Han JC, Guan WL, Wang Q, Zhu L, Pan XB, Wei L
PloS one 2013;8(11):e80769
PloS one 2013;8(11):e80769
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The CNPase antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CNPase. This antibody recognizes human,mouse,rat antigen. The CNPase antibody has been validated for the following applications: ELISA, WB analysis.