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- Antibody Data
- Antigen structure
- References [13]
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- Validations
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- AMAb91072 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#AMAb91072, RRID:AB_2665789
- Product name
- Anti-CNP
- Antibody type
- Monoclonal
- Description
- Monoclonal Antibody against Human CNP, Clone ID: CL2887, Gene description: 2',3'-cyclic nucleotide 3' phosphodiesterase, Validated applications: WB, IHC, ICC, Uniprot ID: P09543, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- CL2887
- Vial size
- 100 µl
- Concentration
- 1.0 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Reflective imaging of myelin integrity in the human and mouse central nervous systems
Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease
Expression patterns of NKCC1 in neurons and non-neuronal cells during cortico-hippocampal development
Astrocyte-oligodendrocyte interaction regulates central nervous system regeneration
Microglia regulate central nervous system myelin growth and integrity
New oligodendrocytes exhibit more abundant and accurate myelin regeneration than those that survive demyelination
Lipid Metabolism Is Dysregulated in the Motor Cortex White Matter in Amyotrophic Lateral Sclerosis
iPSC-derived myelinoids to study myelin biology of humans
Oligodendrocyte HCN2 Channels Regulate Myelin Sheath Length
TDP-43 proteinopathy in oligodendrocytes revealed using an induced pluripotent stem cell model
Staining and Quantitative Analysis of Myelinating Oligodendrocytes in the Mouse Grey Matter
Endothelin signalling mediates experience-dependent myelination in the CNS
Scaffold-Mediated Sustained, Non-viral Delivery of miR-219/miR-338 Promotes CNS Remyelination
Craig G, Ryan L, Thapar J, McNamara N, Hoffmann A, Page D, Rose J, Cox S, Miron V
Frontiers in Cellular Neuroscience 2024;18
Frontiers in Cellular Neuroscience 2024;18
Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease
Depp C, Sun T, Sasmita A, Spieth L, Berghoff S, Nazarenko T, Overhoff K, Steixner-Kumar A, Subramanian S, Arinrad S, Ruhwedel T, Möbius W, Göbbels S, Saher G, Werner H, Damkou A, Zampar S, Wirths O, Thalmann M, Simons M, Saito T, Saido T, Krueger-Burg D, Kawaguchi R, Willem M, Haass C, Geschwind D, Ehrenreich H, Stassart R, Nave K
Nature 2023;618(7964):349-357
Nature 2023;618(7964):349-357
Expression patterns of NKCC1 in neurons and non-neuronal cells during cortico-hippocampal development
Kurki S, Uvarov P, Pospelov A, Trontti K, Hübner A, Srinivasan R, Watanabe M, Hovatta I, Hübner C, Kaila K, Virtanen M
Cerebral Cortex 2023;33(10):5906-5923
Cerebral Cortex 2023;33(10):5906-5923
Astrocyte-oligodendrocyte interaction regulates central nervous system regeneration
Molina-Gonzalez I, Holloway R, Jiwaji Z, Dando O, Kent S, Emelianova K, Lloyd A, Forbes L, Mahmood A, Skripuletz T, Gudi V, Febery J, Johnson J, Fowler J, Kuhlmann T, Williams A, Chandran S, Stangel M, Howden A, Hardingham G, Miron V
Nature Communications 2023;14(1)
Nature Communications 2023;14(1)
Microglia regulate central nervous system myelin growth and integrity
McNamara N, Munro D, Bestard-Cuche N, Uyeda A, Bogie J, Hoffmann A, Holloway R, Molina-Gonzalez I, Askew K, Mitchell S, Mungall W, Dodds M, Dittmayer C, Moss J, Rose J, Szymkowiak S, Amann L, McColl B, Prinz M, Spires-Jones T, Stenzel W, Horsburgh K, Hendriks J, Pridans C, Muramatsu R, Williams A, Priller J, Miron V
Nature 2022;613(7942):120-129
Nature 2022;613(7942):120-129
New oligodendrocytes exhibit more abundant and accurate myelin regeneration than those that survive demyelination
Neely S, Williamson J, Klingseisen A, Zoupi L, Early J, Williams A, Lyons D
Nature Neuroscience 2022;25(4):415-420
Nature Neuroscience 2022;25(4):415-420
Lipid Metabolism Is Dysregulated in the Motor Cortex White Matter in Amyotrophic Lateral Sclerosis
Sadler G, Lewis K, Narayana V, De Souza D, Mason J, McLean C, Gonsalvez D, Turner B, Barton S
Metabolites 2022;12(6):554
Metabolites 2022;12(6):554
iPSC-derived myelinoids to study myelin biology of humans
James O, Selvaraj B, Magnani D, Burr K, Connick P, Barton S, Vasistha N, Hampton D, Story D, Smigiel R, Ploski R, Brophy P, ffrench-Constant C, Lyons D, Chandran S
Developmental Cell 2021;56(9):1346-1358.e6
Developmental Cell 2021;56(9):1346-1358.e6
Oligodendrocyte HCN2 Channels Regulate Myelin Sheath Length
Swire M, Assinck P, McNaughton P, Lyons D, ffrench-Constant C, Livesey M
The Journal of Neuroscience 2021;41(38):7954-7964
The Journal of Neuroscience 2021;41(38):7954-7964
TDP-43 proteinopathy in oligodendrocytes revealed using an induced pluripotent stem cell model
Barton S, Magnani D, James O, Livesey M, Selvaraj B, James O, Perkins E, Gregory J, Cleary E, Ausems C, Carter R, Vasistha N, Zhao C, Burr K, Story D, Cardinali A, Morton N, Hardingham G, Wyllie D, Chandran S
Brain Communications 2021
Brain Communications 2021
Staining and Quantitative Analysis of Myelinating Oligodendrocytes in the Mouse Grey Matter
Swire M, ffrench-Constant C
BIO-PROTOCOL 2020;10(20)
BIO-PROTOCOL 2020;10(20)
Endothelin signalling mediates experience-dependent myelination in the CNS
Swire M, Kotelevtsev Y, Webb D, Lyons D, ffrench-Constant C
eLife 2019;8
eLife 2019;8
Scaffold-Mediated Sustained, Non-viral Delivery of miR-219/miR-338 Promotes CNS Remyelination
Milbreta U, Lin J, Pinese C, Ong W, Chin J, Shirahama H, Mi R, Williams A, Bechler M, Wang J, ffrench-Constant C, Hoke A, Chew S
Molecular Therapy 2019;27(2):411-423
Molecular Therapy 2019;27(2):411-423
No comments: Submit comment
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescence staining of RH-30 cells using the Anti-CNP monoclonal antibody, showing specific staining in the cytosol in green. Microtubule- and nuclear probes are visualized in red and blue, respectively (where available).
- Sample type
- Human
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human cerebral cortex and pancreas tissues using AMAb91072 antibody. Corresponding CNP RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
