ABIN1673357

antibody from antibodies-online

Targeting: CUL2

Western blot (Recommended by provider)

Antibody Data

Product number

ABIN1673357

Provider

antibodies-online

Product name

anti-Cullin 2 (CUL2) (Middle Region) antibody

Antibody type

Polyclonal

Antigen

A synthetic peptide corresponding to a sequence in the middle region of human Cullin 2, different from the related mouse and rat sequences by one amino acid.Immunogen affinity purified.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

Middle Region

Isotype

IgG

Vial size

100 μg

Storage

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Genomic organization and chromosomal localization of the human CUL2 gene and the role of von Hippel-Lindau tumor suppressor-binding protein (CUL2 and VBP1) mutation and loss in renal-cell carcinoma development.

Clifford SC, Walsh S, Hewson K, Green EK, Brinke A, Green PM, Gianelli F, Eng C, Maher ER
Genes, chromosomes & cancer 1999 Sep;26(1):20-8

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Regulation of hypoxia-inducible mRNAs by the von Hippel-Lindau tumor suppressor protein requires binding to complexes containing elongins B/C and Cul2.

Lonergan KM, Iliopoulos O, Ohh M, Kamura T, Conaway RC, Conaway JW, Kaelin WG Jr
Molecular and cellular biology 1998 Feb;18(2):732-41