ABIN1673418

antibody from antibodies-online

Targeting: CUL3

Western blot (Recommended by provider)

Antibody Data

Product number

ABIN1673418

Provider

antibodies-online

Product name

anti-Cullin 3 (CUL3) (Middle Region) antibody

Antibody type

Polyclonal

Antigen

A synthetic peptide corresponding to a sequence in the middle region of human Cullin 3, identical to the related rat and mouse sequences.Immunogen affinity purified.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

Middle Region

Isotype

IgG

Vial size

100 μg

Storage

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Ubiquitin ligase activity of Cul3-KLHL7 protein is attenuated by autosomal dominant retinitis pigmentosa causative mutation.

Kigoshi Y, Tsuruta F, Chiba T
The Journal of biological chemistry 2011 Sep 23;286(38):33613-21

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BTB Protein KLHL12 targets the dopamine D4 receptor for ubiquitination by a Cul3-based E3 ligase.

Rondou P, Haegeman G, Vanhoenacker P, Van Craenenbroeck K
The Journal of biological chemistry 2008 Apr 25;283(17):11083-96

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A Cul3-based E3 ligase removes Aurora B from mitotic chromosomes, regulating mitotic progression and completion of cytokinesis in human cells.

Sumara I, Quadroni M, Frei C, Olma MH, Sumara G, Ricci R, Peter M
Developmental cell 2007 Jun;12(6):887-900