Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations [0]
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- Product number
- ABIN1673418 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Cullin 3 (CUL3) (Middle Region) antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to a sequence in the middle region of human Cullin 3, identical to the related rat and mouse sequences.Immunogen affinity purified.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- Middle Region
- Isotype
- IgG
- Vial size
- 100 μg
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Ubiquitin ligase activity of Cul3-KLHL7 protein is attenuated by autosomal dominant retinitis pigmentosa causative mutation.
BTB Protein KLHL12 targets the dopamine D4 receptor for ubiquitination by a Cul3-based E3 ligase.
A Cul3-based E3 ligase removes Aurora B from mitotic chromosomes, regulating mitotic progression and completion of cytokinesis in human cells.
Kigoshi Y, Tsuruta F, Chiba T
The Journal of biological chemistry 2011 Sep 23;286(38):33613-21
The Journal of biological chemistry 2011 Sep 23;286(38):33613-21
BTB Protein KLHL12 targets the dopamine D4 receptor for ubiquitination by a Cul3-based E3 ligase.
Rondou P, Haegeman G, Vanhoenacker P, Van Craenenbroeck K
The Journal of biological chemistry 2008 Apr 25;283(17):11083-96
The Journal of biological chemistry 2008 Apr 25;283(17):11083-96
A Cul3-based E3 ligase removes Aurora B from mitotic chromosomes, regulating mitotic progression and completion of cytokinesis in human cells.
Sumara I, Quadroni M, Frei C, Olma MH, Sumara G, Ricci R, Peter M
Developmental cell 2007 Jun;12(6):887-900
Developmental cell 2007 Jun;12(6):887-900
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