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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [9]
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- Product number
- ABIN117949 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Cullin 3 (CUL3) (N-Term), (AA 1-12) antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide corresponding to amino acids 1-12 of Human Cul3 (N-terminus) coupled to KLH.
- Description
- Delipidation and defibrination.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Antigen sequence
Human Cullin 3 (768 aa 88.9 kDa): 1
msnlskgtgs rkdtkmrira fpmtmdekyv n
siwdllkna iqeiqrknns glsfeelyrn 61
aytmvlhkhg eklytglrev vtehlinkvr ed
vlnslnnn flqtlnqawn dhqtamvmir 121
dilmymdrvy vqqnnvenvy nlgliifrdq vv
rygcirdh lrqtlldmia rerkgevvdr 181
gairnacqml milglegrsv yeedfeapfl em
saeffqme sqkflaensa svyikkvear 241
ineeiervmh cldksteepi vkvverelis kh
mktiveme nsglvhmlkn gktedlgcmy 301
klfsrvpngl ktmcecmssy lreqgkalvs ee
gegknpvd yiqglldlks rfdrfllesf 361
nndrlfkqti agdfeyflnl nsrspeylsl fi
ddklkkgv kglteqevet ildkamvlfr 421
fmqekdvfer yykqhlarrl ltnksvsdds ek
nmisklkt ecgcqftskl egmfrdmsis 481
nttmdefrqh lqatgvslgg vdltvrvltt gy
wptqsatp kcnippaprh afeifrrfyl 541
akhsgrqltl qhhmgsadln atfygpvkke dg
sevgvgga qvtgsntrkh ilqvstfqmt 601
ilmlfnnrek ytfeeiqqet diperelvra lq
slacgkpt qrvltkepks keienghift 661
vndqftsklh rvkiqtvaak qgesdperke tr
qkvdddrk heieaaivri mksrkkmqhn 721
vlvaevtqql karflpspvv ikkrieglie re
ylartped rkvytyva- Epitope
- N-Term,AA 1-12
- Vial size
- 0.1 mL
- Concentration
- 85.0 mg/mL (by Refractometry)
- Storage
- Store undiluted at 2-8°C for up to one month or at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Sporadic paediatric and adult Burkitt lymphomas share similar phenotypic and genotypic features.
Targeting of protein ubiquitination by BTB-Cullin 3-Roc1 ubiquitin ligases.
Ubiquitin and its kin: how close are the family ties?
Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells.
ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity.
Cloning and expression analysis of a novel salicylate suppressible gene, Hs-CUL-3, a member of cullin/Cdc53 family.
Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A.
cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family.
Cdc53p acts in concert with Cdc4p and Cdc34p to control the G1-to-S-phase transition and identifies a conserved family of proteins.
Chuang SS, Huang WT, Hsieh PP, Jung YC, Ye H, Du MQ, Lu CL, Cho CY, Hsiao SC, Hsu YH, Lin KJ
Histopathology 2008 Mar;52(4):427-35
Histopathology 2008 Mar;52(4):427-35
Targeting of protein ubiquitination by BTB-Cullin 3-Roc1 ubiquitin ligases.
Furukawa M, He YJ, Borchers C, Xiong Y
Nature cell biology 2003 Nov;5(11):1001-7
Nature cell biology 2003 Nov;5(11):1001-7
Ubiquitin and its kin: how close are the family ties?
Jentsch S, Pyrowolakis G
Trends in cell biology 2000 Aug;10(8):335-42
Trends in cell biology 2000 Aug;10(8):335-42
Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells.
Singer JD, Gurian-West M, Clurman B, Roberts JM
Genes & development 1999 Sep 15;13(18):2375-87
Genes & development 1999 Sep 15;13(18):2375-87
ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity.
Ohta T, Michel JJ, Schottelius AJ, Xiong Y
Molecular cell 1999 Apr;3(4):535-41
Molecular cell 1999 Apr;3(4):535-41
Cloning and expression analysis of a novel salicylate suppressible gene, Hs-CUL-3, a member of cullin/Cdc53 family.
Du M, Sansores-Garcia L, Zu Z, Wu KK
The Journal of biological chemistry 1998 Sep 18;273(38):24289-92
The Journal of biological chemistry 1998 Sep 18;273(38):24289-92
Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A.
Michel JJ, Xiong Y
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998 Jun;9(6):435-49
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998 Jun;9(6):435-49
cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family.
Kipreos ET, Lander LE, Wing JP, He WW, Hedgecock EM
Cell 1996 Jun 14;85(6):829-39
Cell 1996 Jun 14;85(6):829-39
Cdc53p acts in concert with Cdc4p and Cdc34p to control the G1-to-S-phase transition and identifies a conserved family of proteins.
Mathias N, Johnson SL, Winey M, Adams AE, Goetsch L, Pringle JR, Byers B, Goebl MG
Molecular and cellular biology 1996 Dec;16(12):6634-43
Molecular and cellular biology 1996 Dec;16(12):6634-43
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