AFC-284CL

antibody from Creative Biolabs

Targeting: GAD2 GAD65

No application information provided.

Antibody Data

Product number

AFC-284CL

Provider

Creative Biolabs

Product name

Afuco? Anti-Human GAD2 ADCC Recombinant Antibody, ADCC Enhanced

Antibody type

Monoclonal

Description

Anti-GAD2 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco? platform. GAD65Ab are common in healthy individuals, but masked by epitope-specific anti-idiotypic antibodies. GAD65Ab may have a pathogenic role in the disease process in patients with Stiff Person Syndrome (SPS). GAD65Ab in SPS patients inhibit the enzyme's activity and result in a deficit in the major inhibitory neurotransmitter GABA, possibly causing clinical symptoms such as muscle spasms and stiffness.

Reactivity

Human

Host

Human

Storage

Store at 4¡ãC for up to 3 months. For longer term storage aliquot into small volumes and store at -20¡ãC.