TAB-297CL

antibody from Creative Biolabs
Targeting: GAD2 GAD65
Provider product page for TAB-297CL
No application information provided.

Antibody data

Product number
TAB-297CL - Provider product page
Provider
Creative Biolabs
Product name
Anti-Human GAD2 Recombinant Antibody
Antibody type
Monoclonal
Description
Recombinant Human monoclonal antibody expressed in CHO binding to Human GAD2. GAD65Ab are common in healthy individuals, but masked by epitope-specific anti-idiotypic antibodiess. GAD65Ab may have a pathogenic role in the disease process in patients with Stiff Person Syndrome (SPS). GAD65Ab in SPS patients inhibit the enzyme's activity and result in a deficit in the major inhibitory neurotransmitter GABA, possibly causing clinical symptoms such as muscle spasms and stiffness.
Reactivity
Human
Storage
Store at 4¡ãC for up to 3 months. For longer term storage aliquot into small volumes and store at -20¡ãC.
GAD2 protein structure - TAB-297CL shown in red.