abx317299

antibody from Abbexa

Targeting: GAD2 GAD65

No application information provided.

Antibody Data

Product number

abx317299

Provider

Abbexa

Product name

Glutamate Decarboxylase 2 (GAD2) Antibody (Biotin)

Antibody type

Polyclonal

Description

Glutamate Decarboxylase 2 (GAD2) Antibody (Biotin) is a Rabbit Polyclonal against Glutamate Decarboxylase 2 (GAD2) conjugated to Biotin. This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.

Reactivity

Human

Host

Rabbit

Conjugate

Biotin

Isotype

IgG

Vial size

100 µg

Storage

Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.