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Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
- ELISA [1]
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- Product number
- RA0140 - Provider product page
- Provider
- Oursmab
- Product name
- Tinurilimab (Biosimilar Reference Antibody) (CEACAM6)
- Antibody type
- Monoclonal
- Description
- Tinurilimab is a humanized IgG2 kappa monoclonal antibody targeting carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6), a glycoprotein overexpressed in many epithelial cancers. It binds to CEACAM6 to block its immunosuppressive function, which normally inhibits effector T cell activity in the tumor microenvironment. It is being developed as an immunomodulatory therapy for CEACAM6-positive solid tumors, such as pancreatic, lung, and colorectal cancers.
- Reactivity
- Human
- Isotype
- IgG
- Vial size
- 100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg
- Concentration
- Bottled at the concentration indicated on the vial.
- Storage
- Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.
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Supportive validation
- Submitted by
- Oursmab (provider)
- Main image
- Experimental details
- Tinurilimab (Biosimilar Reference Antibody) (CEACAM6)-RA0140-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.
Supportive validation
- Submitted by
- Oursmab (provider)
- Main image
- Experimental details
- ELISA plate pre-coated Antigen protein, can bind Tinurilimab (Biosimilar Reference Antibody) (CEACAM6)-RA0140 in a linear range of 15.63¨C125 ng/mL.
