Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 12635-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12635-1-AP, RRID:AB_2111635
- Product name
- GNAO1 antibody
- Antibody type
- Polyclonal
- Description
- GNAO1 antibody (Cat. #12635-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Benzeneboronic acid-modified hyaluronic acid hydrogel enhances the differentiation of dorsal root ganglion stem cells in a three-dimensional environment.
Inhibiting acute, axonal DLK palmitoylation is neuroprotective and avoids deleterious effects of cell-wide DLK inhibition.
Inhibitory G proteins play multiple roles to polarize sensory hair cell morphogenesis.
Inhibitory G proteins play multiple roles to polarize sensory hair cell morphogenesis.
Disruption of the interaction between mutationally activated Gα(q) and Gβγ attenuates aberrant signaling.
A single cell transcriptional roadmap of human pacemaker cell differentiation.
Gene expression and methylation profiles show the involvement of POMC in primary hyperparathyroidsm.
GNAO1 as a Novel Predictive Biomarker for Late Relapse in Hepatocellular Carcinoma.
Identification of functional cooperative mutations of GNAO1 in human acute lymphoblastic leukemia.
DNMT1 mediated promoter methylation of GNAO1 in hepatoma carcinoma cells.
Efficacy of Hybrid Tetrahydrobenzo[d]thiazole Based Aryl Piperazines D-264 and D-301 at D₂ and D₃ Receptors.
Overexpression of GNAO1 correlates with poor prognosis in patients with gastric cancer and plays a role in gastric cancer cell proliferation and apoptosis.
The down-regulation of GNAO1 and its promoting role in hepatocellular carcinoma.
Liu K, Wang H, Wang L, Ma W, Yang J, Li C, Liu J, Bao W, Li L, Du Y, Gao H
International journal of biological macromolecules 2025 May;309(Pt 1):142786
International journal of biological macromolecules 2025 May;309(Pt 1):142786
Inhibiting acute, axonal DLK palmitoylation is neuroprotective and avoids deleterious effects of cell-wide DLK inhibition.
Zhang X, Jeong H, Niu J, Holland SM, Rotanz BN, Gordon J, Einarson MB, Childers WE, Thomas GM
Nature communications 2025 Apr 3;16(1):3031
Nature communications 2025 Apr 3;16(1):3031
Inhibitory G proteins play multiple roles to polarize sensory hair cell morphogenesis.
Jarysta A, Tadenev ALD, Day M, Krawchuk B, Low BE, Wiles MV, Tarchini B
bioRxiv : the preprint server for biology 2024 Jan 6;
bioRxiv : the preprint server for biology 2024 Jan 6;
Inhibitory G proteins play multiple roles to polarize sensory hair cell morphogenesis.
Jarysta A, Tadenev ALD, Day M, Krawchuk B, Low BE, Wiles MV, Tarchini B
eLife 2024 Apr 23;12
eLife 2024 Apr 23;12
Disruption of the interaction between mutationally activated Gα(q) and Gβγ attenuates aberrant signaling.
Aumiller JL, Wedegaertner PB
The Journal of biological chemistry 2023 Feb;299(2):102880
The Journal of biological chemistry 2023 Feb;299(2):102880
A single cell transcriptional roadmap of human pacemaker cell differentiation.
Wiesinger A, Li J, Fokkert L, Bakker P, Verkerk AO, Christoffels VM, Boink GJJ, Devalla HD
eLife 2022 Oct 11;11
eLife 2022 Oct 11;11
Gene expression and methylation profiles show the involvement of POMC in primary hyperparathyroidsm.
Zhou WX, Wang S, Wu TC, Cheng LC, Du Y, Wu W, Lin C, Li XY, Hu ZL
Journal of translational medicine 2022 Aug 16;20(1):368
Journal of translational medicine 2022 Aug 16;20(1):368
GNAO1 as a Novel Predictive Biomarker for Late Relapse in Hepatocellular Carcinoma.
Du M, Feng J, Tao Y, Pan Q, Chen F
Journal of healthcare engineering 2021;2021:7631815
Journal of healthcare engineering 2021;2021:7631815
Identification of functional cooperative mutations of GNAO1 in human acute lymphoblastic leukemia.
Song L, Yu B, Yang Y, Liang J, Zhang Y, Ding L, Wang T, Wan X, Yang X, Tang J, Wang S, Li B, Li Y, Feng H
Blood 2021 Mar 4;137(9):1181-1191
Blood 2021 Mar 4;137(9):1181-1191
DNMT1 mediated promoter methylation of GNAO1 in hepatoma carcinoma cells.
Xu D, Du M, Zhang J, Xiong P, Li W, Zhang H, Xiong W, Liu F, Liu J
Gene 2018 Jul 30;665:67-73
Gene 2018 Jul 30;665:67-73
Efficacy of Hybrid Tetrahydrobenzo[d]thiazole Based Aryl Piperazines D-264 and D-301 at D₂ and D₃ Receptors.
Zhen J, Antonio T, Jacob JC, Grandy DK, Reith MEA, Dutta AK, Selley DE
Neurochemical research 2016 Feb;41(1-2):328-339
Neurochemical research 2016 Feb;41(1-2):328-339
Overexpression of GNAO1 correlates with poor prognosis in patients with gastric cancer and plays a role in gastric cancer cell proliferation and apoptosis.
Liu Z, Zhang J, Wu L, Liu J, Zhang M
International journal of molecular medicine 2014 Mar;33(3):589-96
International journal of molecular medicine 2014 Mar;33(3):589-96
The down-regulation of GNAO1 and its promoting role in hepatocellular carcinoma.
Pei X, Zhang J, Wu L, Lü B, Zhang X, Yang D, Liu J
Bioscience reports 2013 Sep 17;33(5)
Bioscience reports 2013 Sep 17;33(5)
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- human liver tissue were subjected to SDS PAGE followed by western blot with 12635-1-AP(GNAO1 antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The GNAO1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GNAO1. This antibody recognizes human, mouse, rat antigen. The GNAO1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.