Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- MB0127 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- CHRDL1 monoclonal antibody
- Antibody type
- Monoclonal
- Antigen
- Recombinant full length Human CHRDL1.
- Description
- This gene encodes an antagonist of bone morphogenetic protein 4. The encoded protein may play a role in topographic retinotectal projection and in the regulation of retinal angiogenesis in response to hypoxia. Alternatively spliced transcript variants encoding different isoforms have been described. Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embyonic bone formation By similarity. May also play an important role in regulating retinal angiogenesis trough modulation of BMP4 actions in endothelial cells.
- Reactivity
- Human, Mouse, Rat
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
No comments: Submit comment
Supportive validation
- Submitted by
- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot detection of CHRDL1 in Rat kidney tissue lysates using CHRDL1 antibody (1:1000 diluted) .