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- Antigen structure
- References [16]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 12686-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12686-1-AP, RRID:AB_2188001
- Product name
- EAAT3 antibody
- Antibody type
- Polyclonal
- Description
- EAAT3 antibody (Cat. #12686-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Longevity Humans Have Youthful Erythrocyte Function and Metabolic Signatures.
Intracellular metabotropic glutamate receptor 5 in spinal dorsal horn neurons contributes to pain in a mouse model of vincristine-induced neuropathic pain.
NF-κB-mediated EAAT3 upregulation in antioxidant defense and ferroptosis sensitivity in lung cancer.
Geniposide Improves Corticosterone-induced Toxicity in PC12 Cells through the NMDARs and BDNF Pathway.
[Prenatal fear stress impairs cognitive development in offspring rats by disrupting placental amino acid transport].
A combination of Δ(9)-tetrahydrocannabinol and cannabidiol modulates glutamate dynamics in the hippocampus of an animal model of Alzheimer's disease.
Astrocytic neuroligin 3 regulates social memory and synaptic plasticity through adenosine signaling in male mice.
Dietary supplementation of microencapsulated botanicals and organic acids enhances the expression and function of intestine epithelial digestive enzymes and nutrient transporters in broiler chickens.
Arteriovenous metabolomics in pigs reveals CFTR regulation of metabolism in multiple organs.
Geniposide improves depression-like behavior in prenatal stress male offspring through restoring HPA axis- and glucocorticoid receptor-associated dysfunction.
The expression of nutrient chemosensing gate molecules in the ileum and colon is altered for goats fed on a high-grain diet.
L-Theanine Regulates the Abundance of Amino Acid Transporters in Mice Duodenum and Jejunum via the mTOR Signaling Pathway.
Dysregulated Glutamate Transporter SLC1A1 Propels Cystine Uptake via Xc(-) for Glutathione Synthesis in Lung Cancer.
S-Adenosylmethionine Alleviates Amyloid-β-Induced Neural Injury by Enhancing Trans-Sulfuration Pathway Activity in Astrocytes.
Ginsenoside Rb1 confers neuroprotection via promotion of glutamate transporters in a mouse model of Parkinson's disease.
Characterization of GALNTL5 gene sequence and expression in ovine testes and sperm.
Yu F, Chen C, Liu W, Zhao Z, Fan Y, Li Z, Huang W, Xie T, Luo C, Yao Z, Guo Q, Yang Z, Liu J, Zhang Y, Kellems RE, Xia J, Li J, Xia Y
Aging cell 2025 May;24(5):e14482
Aging cell 2025 May;24(5):e14482
Intracellular metabotropic glutamate receptor 5 in spinal dorsal horn neurons contributes to pain in a mouse model of vincristine-induced neuropathic pain.
Li X, Yang H, Qian M, Liu H, Zuo S, Liu JC, Ge WH, Zhou L
Neuroscience letters 2025 Mar 15;852:138193
Neuroscience letters 2025 Mar 15;852:138193
NF-κB-mediated EAAT3 upregulation in antioxidant defense and ferroptosis sensitivity in lung cancer.
Wen D, Li W, Song X, Hu M, Liao Y, Xu D, Deng J, Guo W
Cell death & disease 2025 Feb 22;16(1):124
Cell death & disease 2025 Feb 22;16(1):124
Geniposide Improves Corticosterone-induced Toxicity in PC12 Cells through the NMDARs and BDNF Pathway.
Ma Q, Ma Y, Sun S, Yang L, Shi T, Zhang B, Shang B, Zhou R, Liu J, He J, Hu J, Cao Y
Cell biochemistry and biophysics 2025 Dec;83(4):5387-5400
Cell biochemistry and biophysics 2025 Dec;83(4):5387-5400
[Prenatal fear stress impairs cognitive development in offspring rats by disrupting placental amino acid transport].
DU Z, Wang Y, Yang L, Hou J, Sun J, Fan P, Wang Y, Li X
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2025 Aug 20;45(8):1581-1588
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2025 Aug 20;45(8):1581-1588
A combination of Δ(9)-tetrahydrocannabinol and cannabidiol modulates glutamate dynamics in the hippocampus of an animal model of Alzheimer's disease.
Sánchez-Fernández N, Gómez-Acero L, Castañé A, Adell A, Campa L, Bonaventura J, Brito V, Ginés S, Queiróz F, Silva H, Lopes JP, Lopes CR, Radošević M, Gasull X, Cunha RA, Köfalvi A, Ferreira SG, Ciruela F, Aso E
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2024 Sep;21(5):e00439
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2024 Sep;21(5):e00439
Astrocytic neuroligin 3 regulates social memory and synaptic plasticity through adenosine signaling in male mice.
Dang R, Liu A, Zhou Y, Li X, Wu M, Cao K, Meng Y, Zhang H, Gan G, Xie W, Jia Z
Nature communications 2024 Oct 5;15(1):8639
Nature communications 2024 Oct 5;15(1):8639
Dietary supplementation of microencapsulated botanicals and organic acids enhances the expression and function of intestine epithelial digestive enzymes and nutrient transporters in broiler chickens.
Toschi A, Yu LE, Bialkowski S, Schlitzkus L, Grilli E, Li Y
Poultry science 2024 Nov;103(11):104237
Poultry science 2024 Nov;103(11):104237
Arteriovenous metabolomics in pigs reveals CFTR regulation of metabolism in multiple organs.
Bae H, Kim BR, Jung S, Le J, van der Heide D, Yu W, Park SH, Hilkin BM, Gansemer ND, Powers LS, Kang T, Meyerholz DK, Schuster VL, Jang C, Welsh MJ
The Journal of clinical investigation 2024 May 14;134(13)
The Journal of clinical investigation 2024 May 14;134(13)
Geniposide improves depression-like behavior in prenatal stress male offspring through restoring HPA axis- and glucocorticoid receptor-associated dysfunction.
Ma Y, Li SX, Zhou RY, Deng LJ, le He W, Guo LL, Wang L, Hao JH, Li Y, Fang MF, Cao YJ
Life sciences 2024 Mar 1;340:122434
Life sciences 2024 Mar 1;340:122434
The expression of nutrient chemosensing gate molecules in the ileum and colon is altered for goats fed on a high-grain diet.
Tian C, Wu J, Jiao J, Zhou C, Tan Z
Animal science journal = Nihon chikusan Gakkaiho 2022 Jan-Dec;93(1):e13754
Animal science journal = Nihon chikusan Gakkaiho 2022 Jan-Dec;93(1):e13754
L-Theanine Regulates the Abundance of Amino Acid Transporters in Mice Duodenum and Jejunum via the mTOR Signaling Pathway.
Liu K, Peng Y, Lin L, Gong Z, Xiao W, Li Y
Nutrients 2022 Dec 28;15(1)
Nutrients 2022 Dec 28;15(1)
Dysregulated Glutamate Transporter SLC1A1 Propels Cystine Uptake via Xc(-) for Glutathione Synthesis in Lung Cancer.
Guo W, Li K, Sun B, Xu D, Tong L, Yin H, Liao Y, Song H, Wang T, Jing B, Hu M, Liu S, Kuang Y, Ling J, Li Q, Wu Y, Wang Q, Yao F, Zhou BP, Lin SH, Deng J
Cancer research 2021 Feb 1;81(3):552-566
Cancer research 2021 Feb 1;81(3):552-566
S-Adenosylmethionine Alleviates Amyloid-β-Induced Neural Injury by Enhancing Trans-Sulfuration Pathway Activity in Astrocytes.
Wan X, Ma B, Wang X, Guo C, Sun J, Cui J, Li L
Journal of Alzheimer's disease : JAD 2020;76(3):981-995
Journal of Alzheimer's disease : JAD 2020;76(3):981-995
Ginsenoside Rb1 confers neuroprotection via promotion of glutamate transporters in a mouse model of Parkinson's disease.
Zhang YL, Liu Y, Kang XP, Dou CY, Zhuo RG, Huang SQ, Peng L, Wen L
Neuropharmacology 2018 Mar 15;131:223-237
Neuropharmacology 2018 Mar 15;131:223-237
Characterization of GALNTL5 gene sequence and expression in ovine testes and sperm.
Yao X, Yang H, Zhang Y, Ren C, Nie H, Fan Y, Zhou W, Wang S, Feng X, Wang F
Theriogenology 2017 Jun;95:54-61
Theriogenology 2017 Jun;95:54-61
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse ovary tissue were subjected to SDS PAGE followed by western blot with 12686-1-AP(SLC1A1 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 12686-1-AP(SLC1A1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The EAAT3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human EAAT3. This antibody recognizes human,mouse,rat antigen. The EAAT3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
