Antibody data
- Antibody Data
- Antigen structure
- References [18]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
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Validation data
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- Product number
- 18008-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18008-1-AP, RRID:AB_2146541
- Product name
- MME,CD10 antibody
- Antibody type
- Polyclonal
- Description
- MME,CD10 antibody (Cat. #18008-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Amyloid-β exposed astrocytes induce iron transport from endothelial cells at the blood-brain barrier by altering the ratio of apo- and holo-transferrin.
Bone Marrow-Derived GCA(+) Immune Cells Drive Alzheimer's Disease Progression.
Novel aspect of neprilysin in kidney fibrosis via ACSL4-mediated ferroptosis of tubular epithelial cells.
Clinical Impact of the Histopathological Index and Neuroimaging Features Status in Primary Central Nervous System Diffuse Large B-Cell Lymphoma: A Single-Center Retrospective Analysis of 51 Cases.
The presence of living endometrial cells in ovarian endometriotic cyst fluid may contribute to the recurrence of endometriosis after surgical excision of endometriomas.
A novel nude mouse model for studying the pathogenesis of endometriosis.
Ameliorating Ribosylation-Induced Amyloid-β Pathology by Berberine via Inhibiting mTOR/p70S6K Signaling.
Metformin attenuates vascular pathology by increasing expression of insulin-degrading enzyme in a mixed model of cerebral amyloid angiopathy and type 2 diabetes mellitus.
Bone marrow mesenchymal stem cells-derived exosomes reduce Aβ deposition and improve cognitive function recovery in mice with Alzheimer's disease by activating sphingosine kinase/sphingosine-1-phosphate signaling pathway.
Dendrobium nobile Lindl. Alkaloids Ameliorate Cognitive Dysfunction in Senescence Accelerated SAMP8 Mice by Decreasing Amyloid-β Aggregation and Enhancing Autophagy Activity.
Sodium Butyrate Protects N2a Cells against Aβ Toxicity In Vitro.
A novel pectin from Polygala tenuifolia blocks Aβ(42) aggregation and production by enhancing insulin-degradation enzyme and neprilysin.
Overexpression of B7-H4 promotes renal cell carcinoma progression by recruiting tumor-associated neutrophils via upregulation of CXCL8.
MMP13 inhibition rescues cognitive decline in Alzheimer transgenic mice via BACE1 regulation.
Memantine, a Noncompetitive N-Methyl-D-Aspartate Receptor Antagonist, Attenuates Cerebral Amyloid Angiopathy by Increasing Insulin-Degrading Enzyme Expression.
Activation of α7 nicotinic acetylcholine receptor alleviates Aβ(1-42)-induced neurotoxicity via downregulation of p38 and JNK MAPK signaling pathways.
Recombinant soluble neprilysin reduces amyloid-beta accumulation and improves memory impairment in Alzheimer's disease mice.
Genetic control of renal tumorigenesis by the mouse Rtm1 locus.
Baringer SL, Lukacher AS, Palsa K, Kim H, Lippmann ES, Spiegelman VS, Simpson IA, Connor JR
bioRxiv : the preprint server for biology 2023 May 17;
bioRxiv : the preprint server for biology 2023 May 17;
Bone Marrow-Derived GCA(+) Immune Cells Drive Alzheimer's Disease Progression.
Zhou R, Wang L, Chen L, Feng X, Zhou R, Xiang P, Wen J, Huang Y, Zhou H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(36):e2303402
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(36):e2303402
Novel aspect of neprilysin in kidney fibrosis via ACSL4-mediated ferroptosis of tubular epithelial cells.
Lai W, Huang R, Wang B, Shi M, Guo F, Li L, Ren Q, Tao S, Fu P, Ma L
MedComm 2023 Aug;4(4):e330
MedComm 2023 Aug;4(4):e330
Clinical Impact of the Histopathological Index and Neuroimaging Features Status in Primary Central Nervous System Diffuse Large B-Cell Lymphoma: A Single-Center Retrospective Analysis of 51 Cases.
Qi Z, Duan L, Yuan G, Liu J, Li J, Li G, Yu Y, Xu Y, Ma S, Pan Y, Zhang Y
Frontiers in oncology 2022;12:769895
Frontiers in oncology 2022;12:769895
The presence of living endometrial cells in ovarian endometriotic cyst fluid may contribute to the recurrence of endometriosis after surgical excision of endometriomas.
Xu X, Chen Y, Yu Q, Wang J, Xu P, Zhu L, Xu Q, Zhang J, Cui S, Yu K, Li T, Guo X, Zhang X
Journal of ovarian research 2022 Jul 30;15(1):89
Journal of ovarian research 2022 Jul 30;15(1):89
A novel nude mouse model for studying the pathogenesis of endometriosis.
Li LP, Li ZM, Wang ZZ, Cheng YF, He DM, Chen G, Cao BN, Zou Y, Luo Y
Experimental and therapeutic medicine 2022 Aug;24(2):498
Experimental and therapeutic medicine 2022 Aug;24(2):498
Ameliorating Ribosylation-Induced Amyloid-β Pathology by Berberine via Inhibiting mTOR/p70S6K Signaling.
Wang YY, Yan Q, Huang ZT, Zou Q, Li J, Yuan MH, Wu LQ, Cai ZY
Journal of Alzheimer's disease : JAD 2021;79(2):833-844
Journal of Alzheimer's disease : JAD 2021;79(2):833-844
Metformin attenuates vascular pathology by increasing expression of insulin-degrading enzyme in a mixed model of cerebral amyloid angiopathy and type 2 diabetes mellitus.
Inoue Y, Masuda T, Misumi Y, Ando Y, Ueda M
Neuroscience letters 2021 Sep 25;762:136136
Neuroscience letters 2021 Sep 25;762:136136
Bone marrow mesenchymal stem cells-derived exosomes reduce Aβ deposition and improve cognitive function recovery in mice with Alzheimer's disease by activating sphingosine kinase/sphingosine-1-phosphate signaling pathway.
Wang X, Yang G
Cell biology international 2021 Apr;45(4):775-784
Cell biology international 2021 Apr;45(4):775-784
Dendrobium nobile Lindl. Alkaloids Ameliorate Cognitive Dysfunction in Senescence Accelerated SAMP8 Mice by Decreasing Amyloid-β Aggregation and Enhancing Autophagy Activity.
Lv LL, Liu B, Liu J, Li LS, Jin F, Xu YY, Wu Q, Liu J, Shi JS
Journal of Alzheimer's disease : JAD 2020;76(2):657-669
Journal of Alzheimer's disease : JAD 2020;76(2):657-669
Sodium Butyrate Protects N2a Cells against Aβ Toxicity In Vitro.
Sun J, Yuan B, Wu Y, Gong Y, Guo W, Fu S, Luan Y, Wang W
Mediators of inflammation 2020;2020:7605160
Mediators of inflammation 2020;2020:7605160
A novel pectin from Polygala tenuifolia blocks Aβ(42) aggregation and production by enhancing insulin-degradation enzyme and neprilysin.
Zeng H, Li P, Zhou L, Ding K
International journal of biological macromolecules 2020 Oct 15;161:35-43
International journal of biological macromolecules 2020 Oct 15;161:35-43
Overexpression of B7-H4 promotes renal cell carcinoma progression by recruiting tumor-associated neutrophils via upregulation of CXCL8.
Li A, Zhang N, Zhao Z, Chen Y, Zhang L
Oncology letters 2020 Aug;20(2):1535-1544
Oncology letters 2020 Aug;20(2):1535-1544
MMP13 inhibition rescues cognitive decline in Alzheimer transgenic mice via BACE1 regulation.
Zhu BL, Long Y, Luo W, Yan Z, Lai YJ, Zhao LG, Zhou WH, Wang YJ, Shen LL, Liu L, Deng XJ, Wang XF, Sun F, Chen GJ
Brain : a journal of neurology 2019 Jan 1;142(1):176-192
Brain : a journal of neurology 2019 Jan 1;142(1):176-192
Memantine, a Noncompetitive N-Methyl-D-Aspartate Receptor Antagonist, Attenuates Cerebral Amyloid Angiopathy by Increasing Insulin-Degrading Enzyme Expression.
Inoue Y, Ueda M, Masuda T, Misumi Y, Yamashita T, Ando Y
Molecular neurobiology 2019 Dec;56(12):8573-8588
Molecular neurobiology 2019 Dec;56(12):8573-8588
Activation of α7 nicotinic acetylcholine receptor alleviates Aβ(1-42)-induced neurotoxicity via downregulation of p38 and JNK MAPK signaling pathways.
Chang KW, Zong HF, Ma KG, Zhai WY, Yang WN, Hu XD, Xu JH, Chen XL, Ji SF, Qian YH
Neurochemistry international 2018 Nov;120:238-250
Neurochemistry international 2018 Nov;120:238-250
Recombinant soluble neprilysin reduces amyloid-beta accumulation and improves memory impairment in Alzheimer's disease mice.
Park MH, Lee JK, Choi S, Ahn J, Jin HK, Park JS, Bae JS
Brain research 2013 Sep 5;1529:113-24
Brain research 2013 Sep 5;1529:113-24
Genetic control of renal tumorigenesis by the mouse Rtm1 locus.
Jensen JR, Galvan A, Borrego A, Cabrera WH, Ribeiro OG, Starobinas N, De Franco M, Colecchia M, Bertolotti A, Dragani TA, Ibañez OC
BMC genomics 2013 Oct 22;14(1):724
BMC genomics 2013 Oct 22;14(1):724
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse kidney tissue were subjected to SDS PAGE followed by western blot with 18008-1-AP(MME,CD10 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-MME,CD10 (IP:18008-1-AP, 3ug; Detection:18008-1-AP 1:500) with Raji cells lysate 2400ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 18008-1-AP(MME,CD10 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 18008-1-AP(MME,CD10 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MME,CD10 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MME,CD10. This antibody recognizes human,mouse,rat antigen. The MME,CD10 antibody has been validated for the following applications: ELISA, WB, IHC, IP, FC analysis.