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- Antibody Data
- Antigen structure
- References [1]
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- Validations
- Flow cytometry [1]
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- Product number
- 312202 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#312202, RRID:AB_314913
- Product name
- Purified anti-human CD10
- Antibody type
- Monoclonal
- Antigen
- CD10
- Description
- CD10 is a 100 kD neutral endopeptidase and a member of the metalloprotease family. It is a type II transmembrane protein also known as common acute lymphoblastic leukemia antigen (CALLA), enkephalinase, and neprilysin. CD10 is expressed on B cell precursors, T cell precursors, and neutrophils. CD10 is involved in B cell development and has been shown to bind opioid enkephalins, bradykinin, angiotensins I and II, and other biologically active peptides.
- Reactivity
- Human, Simian
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C.
Submitted references A distinct subset of proinflammatory neutrophils isolated from patients with systemic lupus erythematosus induces vascular damage and synthesizes type I IFNs.
Denny MF, Yalavarthi S, Zhao W, Thacker SG, Anderson M, Sandy AR, McCune WJ, Kaplan MJ
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 15;184(6):3284-97
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 15;184(6):3284-97
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Nalm-6 cell line stained with purified HI10a and detected with anti-mouse IgGs-FITC
- Conjugate
- Unconjugated
