Antibody data

Product number
NBP2-44389 - Provider product page
Provider
Novus Biologicals
Product name
Mouse Monoclonal Melan-A/MART-1 Antibody
Antibody type
Monoclonal
Description
Protein A or G purified. This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
Reactivity
Human, Mouse, Rat
Host
Mouse
Isotype
IgG
Vial size
7 ml
Storage
Store at 4C.
MLANA protein structure - NBP2-44389 shown in red.