M02033

antibody from Boster Biological Technology
Targeting: MLANA MART1
Provider product page for M02033
Immunohistochemistry

Antibody data

Product number
M02033 - Provider product page
Provider
Boster Biological Technology
Product name
Anti-MART-1 / Melan-A / MLANA (Melanoma Marker) Monoclonal Antibody
Antibody type
Monoclonal
Description
Mouse Monoclonal Antibody [Clone SPM342] antibody for MART 1/MLANA detection. Host: Mouse.Size: 100ug/vial. Tested applications: IF. Reactive species: Equine. MART 1/MLANA information: Molecular Weight: 13157 MW; Subcellular Localization: Endoplasmic reticulum membrane; Single-pass type III membrane protein. Golgi apparatus. Golgi apparatus, trans-Golgi network membrane. Melanosome. Also found in small vesicles and tubules dispersed over the entire cytoplasm. A small fraction of the protein is inserted into the membrane in an inverted orientation. Inversion of membrane topology results in the relocalization of the protein from a predominant Golgi/post- Golgi area to the endoplasmic reticulum. Melanoma cells expressing the protein with an inverted membrane topology are more effectively recognized by specific cytolytic T-lymphocytes than those expressing the protein in its native membrane orientation; Tissue Specificity: Expression is restricted to melanoma and melanocyte cell lines and retina.
Reactivity
Human
Host
Mouse
Antibody clone number
SPM342
Vial size
100ug/vial
Concentration
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
MLANA protein structure - M02033 shown in red.