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- Antibody Data
- Antigen structure
- References [20]
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- Validations
- Immunoprecipitation [1]
- Immunohistochemistry [1]
- Other assay [1]
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- Product number
- MA5-14017 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Melan-A Antibody Cocktail
- Antibody type
- Monoclonal
- Antigen
- Recombinant full-length protein
- Description
- MA5-14017 targets MART-1 in IHC (P), IP, and WB applications and shows reactivity with Equine and Human samples. The MA5-14017 immunogen is recombinant hMART-1 protein.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- M2-7C10, M2-9E3
- Vial size
- 500 µL
- Concentration
- 0.1 mg/mL
- Storage
- 4°C
Submitted references Vaccination with antigen-transfected, NKT cell ligand-loaded, human cells elicits robust in situ immune responses by dendritic cells.
Ambiguous melanocytic tumors in a tertiary referral center: the contribution of fluorescence in situ hybridization (FISH) to conventional histopathologic and immunophenotypic analyses.
Characterization of the bioactive motif of neuregulin-1, a fibroblast-derived paracrine factor that regulates the constitutive color and the function of melanocytes in human skin.
Intraglomerular crescentic metastases of malignant melanoma.
Expression of the embryological morphogen Nodal in stage III/IV melanoma.
Cellular blue nevus of the uterus: a case report and review of the literature.
Glycoprotein nonmetastatic melanoma protein b, a melanocytic cell marker, is a melanosome-specific and proteolytically released protein.
Regulation of human skin pigmentation in situ by repetitive UV exposure: molecular characterization of responses to UVA and/or UVB.
Vaccine-specific local T cell reactivity in immunotherapy-associated vitiligo in melanoma patients.
Cyclobutane pyrimidine dimer formation and p53 production in human skin after repeated UV irradiation.
Dendritic cell vaccine with mRNA targeted to the proteasome by polyubiquitination.
Glomus tumor and glomangioma of the nerve. Report of two cases.
Diagnostic challenges of metastatic spindle cell melanoma on fine-needle aspiration specimens.
McCune-Albright syndrome in a boy may present with a monolateral macroorchidism as an early and isolated clinical manifestation.
Mechanisms of skin tanning in different racial/ethnic groups in response to ultraviolet radiation.
Immunogenicity, including vitiligo, and feasibility of vaccination with autologous GM-CSF-transduced tumor cells in metastatic melanoma patients.
MART-1 is required for the function of the melanosomal matrix protein PMEL17/GP100 and the maturation of melanosomes.
On the role of melanoma-specific CD8+ T-cell immunity in disease progression of advanced-stage melanoma patients.
Magnetic bead RT-PCR: establishment of a new method for detecting circulating melanoma cells.
Magnetic bead RT-PCR: establishment of a new method for detecting circulating melanoma cells.
Shimizu K, Mizuno T, Shinga J, Asakura M, Kakimi K, Ishii Y, Masuda K, Maeda T, Sugahara H, Sato Y, Matsushita H, Nishida K, Hanada K, Dorrie J, Schaft N, Bickham K, Koike H, Ando T, Nagai R, Fujii S
Cancer research 2013 Jan 1;73(1):62-73
Cancer research 2013 Jan 1;73(1):62-73
Ambiguous melanocytic tumors in a tertiary referral center: the contribution of fluorescence in situ hybridization (FISH) to conventional histopathologic and immunophenotypic analyses.
Tetzlaff MT, Wang WL, Milless TL, Curry JL, Torres-Cabala CA, McLemore MS, Ivan D, Bassett RL, Prieto VG
The American journal of surgical pathology 2013 Dec;37(12):1783-96
The American journal of surgical pathology 2013 Dec;37(12):1783-96
Characterization of the bioactive motif of neuregulin-1, a fibroblast-derived paracrine factor that regulates the constitutive color and the function of melanocytes in human skin.
Choi W, Kolbe L, Hearing VJ
Pigment cell & melanoma research 2012 Jul;25(4):477-81
Pigment cell & melanoma research 2012 Jul;25(4):477-81
Intraglomerular crescentic metastases of malignant melanoma.
Ozluk Y, Kilicaslan I, Kazancioglu R, Demirkesen C, Derin D, Mandel NM
Human pathology 2011 Dec;42(12):2025-8
Human pathology 2011 Dec;42(12):2025-8
Expression of the embryological morphogen Nodal in stage III/IV melanoma.
Hooijkaas AI, Gadiot J, van Boven H, Blank C
Melanoma research 2011 Dec;21(6):491-501
Melanoma research 2011 Dec;21(6):491-501
Cellular blue nevus of the uterus: a case report and review of the literature.
Eskue K, Prieto VG, Malpica A
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2010 Nov;29(6):583-6
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2010 Nov;29(6):583-6
Glycoprotein nonmetastatic melanoma protein b, a melanocytic cell marker, is a melanosome-specific and proteolytically released protein.
Hoashi T, Sato S, Yamaguchi Y, Passeron T, Tamaki K, Hearing VJ
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 May;24(5):1616-29
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 May;24(5):1616-29
Regulation of human skin pigmentation in situ by repetitive UV exposure: molecular characterization of responses to UVA and/or UVB.
Choi W, Miyamura Y, Wolber R, Smuda C, Reinhold W, Liu H, Kolbe L, Hearing VJ
The Journal of investigative dermatology 2010 Jun;130(6):1685-96
The Journal of investigative dermatology 2010 Jun;130(6):1685-96
Vaccine-specific local T cell reactivity in immunotherapy-associated vitiligo in melanoma patients.
Jacobs JF, Aarntzen EH, Sibelt LA, Blokx WA, Boullart AC, Gerritsen MJ, Hoogerbrugge PM, Figdor CG, Adema GJ, Punt CJ, de Vries IJ
Cancer immunology, immunotherapy : CII 2009 Jan;58(1):145-51
Cancer immunology, immunotherapy : CII 2009 Jan;58(1):145-51
Cyclobutane pyrimidine dimer formation and p53 production in human skin after repeated UV irradiation.
Yamaguchi Y, Coelho SG, Zmudzka BZ, Takahashi K, Beer JZ, Hearing VJ, Miller SA
Experimental dermatology 2008 Nov;17(11):916-24
Experimental dermatology 2008 Nov;17(11):916-24
Dendritic cell vaccine with mRNA targeted to the proteasome by polyubiquitination.
Hosoi A, Takeda Y, Sakuta K, Ueha S, Kurachi M, Kimura K, Maekawa R, Kakimi K
Biochemical and biophysical research communications 2008 Jun 27;371(2):242-6
Biochemical and biophysical research communications 2008 Jun 27;371(2):242-6
Glomus tumor and glomangioma of the nerve. Report of two cases.
Scheithauer BW, Rodriguez FJ, Spinner RJ, Dyck PJ, Salem A, Edelman FL, Amrami KK, Fu YS
Journal of neurosurgery 2008 Feb;108(2):348-56
Journal of neurosurgery 2008 Feb;108(2):348-56
Diagnostic challenges of metastatic spindle cell melanoma on fine-needle aspiration specimens.
Piao Y, Guo M, Gong Y
Cancer 2008 Apr 25;114(2):94-101
Cancer 2008 Apr 25;114(2):94-101
McCune-Albright syndrome in a boy may present with a monolateral macroorchidism as an early and isolated clinical manifestation.
Arrigo T, Pirazzoli P, De Sanctis L, Leone O, Wasniewska M, Messina MF, De Luca F
Hormone research 2006;65(3):114-9
Hormone research 2006;65(3):114-9
Mechanisms of skin tanning in different racial/ethnic groups in response to ultraviolet radiation.
Tadokoro T, Yamaguchi Y, Batzer J, Coelho SG, Zmudzka BZ, Miller SA, Wolber R, Beer JZ, Hearing VJ
The Journal of investigative dermatology 2005 Jun;124(6):1326-32
The Journal of investigative dermatology 2005 Jun;124(6):1326-32
Immunogenicity, including vitiligo, and feasibility of vaccination with autologous GM-CSF-transduced tumor cells in metastatic melanoma patients.
Luiten RM, Kueter EW, Mooi W, Gallee MP, Rankin EM, Gerritsen WR, Clift SM, Nooijen WJ, Weder P, van de Kasteele WF, Sein J, van den Berk PC, Nieweg OE, Berns AM, Spits H, de Gast GC
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005 Dec 10;23(35):8978-91
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005 Dec 10;23(35):8978-91
MART-1 is required for the function of the melanosomal matrix protein PMEL17/GP100 and the maturation of melanosomes.
Hoashi T, Watabe H, Muller J, Yamaguchi Y, Vieira WD, Hearing VJ
The Journal of biological chemistry 2005 Apr 8;280(14):14006-16
The Journal of biological chemistry 2005 Apr 8;280(14):14006-16
On the role of melanoma-specific CD8+ T-cell immunity in disease progression of advanced-stage melanoma patients.
van Oijen M, Bins A, Elias S, Sein J, Weder P, de Gast G, Mallo H, Gallee M, Van Tinteren H, Schumacher T, Haanen J
Clinical cancer research : an official journal of the American Association for Cancer Research 2004 Jul 15;10(14):4754-60
Clinical cancer research : an official journal of the American Association for Cancer Research 2004 Jul 15;10(14):4754-60
Magnetic bead RT-PCR: establishment of a new method for detecting circulating melanoma cells.
Georgieva J, Milling A, Orfanos CE, Geilen CC
Melanoma research 2002 Aug;12(4):309-17
Melanoma research 2002 Aug;12(4):309-17
Magnetic bead RT-PCR: establishment of a new method for detecting circulating melanoma cells.
Georgieva J, Milling A, Orfanos CE, Geilen CC
Melanoma research 2002 Aug;12(4):309-17
Melanoma research 2002 Aug;12(4):309-17
No comments: Submit comment
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunoprecipitation of MART-1 using MART-1 Monoclonal Antibody (Product # MA5-14017) on denatured Human CaC1 Cells.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Formalin-fixed, paraffin-embedded human compound nevus stained with MART-1 antibody using peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining of melanocytes.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunoprecipitation of MART-1 using MART-1 Monoclonal Antibody (Product # MA5-14017) on denatured Human CaC1 Cells.
