66391-1-Ig

antibody from Proteintech Group

Targeting: CCNA2 CCN1, CCNA

Provider product page for 66391-1-Ig

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Immunocytochemistry

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [26]
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Product number: 66391-1-Ig - Provider product page
Provider: Proteintech Group
Product name: Cyclin A2 antibody
Antibody type: Monoclonal
Description: KD/KO validated Cyclin A2 antibody (Cat. #66391-1-Ig) is a mouse monoclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB,ELISA.
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Antibody clone number: 1C6C11
Vial size: 20ul, 150ul

CCNA2 protein structure - 66391-1-Ig shown in red.

Submitted references STIM1 translocation to the nucleus protects cells from DNA damage.

Sanchez-Lopez I, Orantos-Aguilera Y, Pozo-Guisado E, Alvarez-Barrientos A, Lilla S, Zanivan S, Lachaud C, Martin-Romero FJ
Nucleic acids research 2024 Mar 21;52(5):2389-2415

Novel Dihydropteridinone Derivatives As Potent Inhibitors of the Understudied Human Kinases Vaccinia-Related Kinase 1 and Casein Kinase 1δ/ε.

de Souza Gama FH, Dutra LA, Hawgood M, Dos Reis CV, Serafim RAM, Ferreira MA Jr, Teodoro BVM, Takarada JE, Santiago AS, Balourdas DI, Nilsson AS, Urien B, Almeida VM, Gileadi C, Ramos PZ, Salmazo A, Vasconcelos SNS, Cunha MR, Mueller S, Knapp S, Massirer KB, Elkins JM, Gileadi O, Mascarello A, Lemmens BBLG, Guimarães CRW, Azevedo H, Couñago RM
Journal of medicinal chemistry 2024 Jun 13;67(11):8609-8629

Combined untargeted metabolomics and network pharmacology approaches to reveal the therapeutic role of withanolide B in psoriasis.

Li T, Gao S, Wei Y, Wu G, Feng Y, Wang Y, Jiang X, Kuang H, Han W
Journal of pharmaceutical and biomedical analysis 2024 Aug 1;245:116163

Adipocyte-Derived Exosomal NOX4-Mediated Oxidative Damage Induces Premature Placental Senescence in Obese Pregnancy.

Tao Y, Chen W, Xu H, Xu J, Yang H, Luo X, Chen M, He J, Bai Y, Qi H
International journal of nanomedicine 2023;18:4705-4726

Upregulation of HCFC1 expression promoted hepatocellular carcinoma progression through inhibiting cell cycle arrest and correlated with immune infiltration.

Wang H, Yu M, Yang C, Li Q
Journal of Cancer 2023;14(8):1381-1397

Osteogenic microenvironment affects palatal development through glycolysis.

Peng X, Chen J, Wang Y, Wang X, Zhao X, Zheng X, Wang Z, Yuan D, Du J
Differentiation; research in biological diversity 2023 Sep-Oct;133:1-11

The HNF4A-CHPF pathway promotes proliferation and invasion through interactions with MAD1L1 in glioma.

Luo H, Huang K, Cheng M, Long X, Zhu X, Wu M
Aging 2023 Oct 17;15(20):11052-11066

A Potential Anti-Glioblastoma Compound LH20 Induces Apoptosis and Arrest of Human Glioblastoma Cells via CDK4/6 Inhibition.

Wang Y, Li Y, Liu D, Zheng D, Li X, Li C, Huang C, Wang Y, Wang X, Li Q, Xu J
Molecules (Basel, Switzerland) 2023 Jun 28;28(13)

Downregulation of miR‑7 and miR‑153 is involved in Helicobacter pylori CagA induced gastric carcinogenesis and progression.

Song Y, Guo D, Liu JF, Ge LN, Liu P, Qu YM, Cong HY, Li T, Chang X, Wang YR, Shao LY, Du ZJ, Wang MY
International journal of oncology 2023 Jul;63(1)

Paradol Induces Cell Cycle Arrest and Apoptosis in Glioblastoma Cells.

Wang R, Liu T, Chen J, Zhang D
Nutrition and cancer 2022;74(8):3007-3014

Alpha1B-adreneroceptor is involved in norepinephrine-induced pulmonary artery smooth muscle cell proliferation via p38 signaling.

Xiao X, Zhang Y, Tian S, Wang X, Zhang Q, Zhang L, Yu X, Ma C, Zheng X, Li Y, Zhang J, Qu L
European journal of pharmacology 2022 Sep 15;931:175159

In vitro and in vivo anti-lymphoma effects of Ophiorrhiza pumila extract.

Fan L, Liao W, Chen Z, Li S, Yang A, Chen MM, Liu H, Liu F
Aging 2022 May 3;14(9):3801-3812

METTL3 promotes homologous recombination repair and modulates chemotherapeutic response in breast cancer by regulating the EGF/RAD51 axis.

Li E, Xia M, Du Y, Long K, Ji F, Pan F, He L, Hu Z, Guo Z
eLife 2022 May 3;11

HDAC7 promotes NSCLC proliferation and metastasis via stabilization by deubiquitinase USP10 and activation of β-catenin-FGF18 pathway.

Guo K, Ma Z, Zhang Y, Han L, Shao C, Feng Y, Gao F, Di S, Zhang Z, Zhang J, Tabbò F, Ekman S, Suda K, Cappuzzo F, Han J, Li X, Yan X
Journal of experimental & clinical cancer research : CR 2022 Mar 11;41(1):91

Role of ferroptosis-related genes in coronary atherosclerosis and identification of key genes: integration of bioinformatics analysis and experimental validation.

Meng Q, Xu Y, Ling X, Liu H, Ding S, Wu H, Yan D, Fang X, Li T, Liu Q
BMC cardiovascular disorders 2022 Jul 29;22(1):339

Hsa_circ_0005050 interacts with ILF3 and affects cell apoptosis and proliferation by disrupting the balance between p53 and p65.

Tan J, Sun M, Yin J, Zhou Q, Zhao R, Chen Q, Sun H, Jiang C, Li S, He Y
Chemico-biological interactions 2022 Dec 1;368:110208

Cannabisin D from Sinomenium Acutum Inhibits Proliferation and Migration of Glioblastoma Cells through MAPKs Signaling.

Zhang D, Li C, Zhang L, Li B, Wang Y, Wang R, Chen Z, Xu L, Liu T
Nutrition and cancer 2021;73(11-12):2491-2501

Combined Treatment of Cinobufotalin and Gefitinib Exhibits Potent Efficacy against Lung Cancer.

Han Y, Ma R, Cao G, Liu H, He L, Tang L, Li H, Luo Q
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6612365

NT5DC2 promotes leiomyosarcoma tumour cell growth via stabilizing unpalmitoylated TEAD4 and generating a positive feedback loop.

Hu B, Zhou S, Hu X, Zhang H, Lan X, Li M, Wang Y, Hu Q
Journal of cellular and molecular medicine 2021 Jul;25(13):5976-5987

Triptolidenol, isolated from Tripterygium wilfordii, disrupted NF-κB/COX-2 pathway by targeting ATP-binding sites of IKKβ in clear cell renal cell carcinoma.

Jin J, Zhou M, Wang X, Liu M, Huang H, Yan F, Yu Z, Shu X, Huo X, Feng L, Zhang B, Huang S, Deng S, Wang C, Ma X
Fitoterapia 2021 Jan;148:104779

Cell division cycle associated 8: A novel diagnostic and prognostic biomarker for hepatocellular carcinoma.

Cui XH, Peng QJ, Li RZ, Lyu XJ, Zhu CF, Qin XH
Journal of cellular and molecular medicine 2021 Dec;25(24):11097-11112

Cell cycle regulation of ER membrane biogenesis protects against chromosome missegregation.

Merta H, Carrasquillo Rodríguez JW, Anjur-Dietrich MI, Vitale T, Granade ME, Harris TE, Needleman DJ, Bahmanyar S
Developmental cell 2021 Dec 20;56(24):3364-3379.e10

A Mechanism of Action Study on Danggui Sini Decoction to Discover Its Therapeutic Effect on Gastric Cancer.

Pan B, Wang Y, Wu C, Jia J, Huang C, Fang S, Liu L
Frontiers in pharmacology 2020;11:592903

KCTD12 promotes tumorigenesis by facilitating CDC25B/CDK1/Aurora A-dependent G2/M transition.

Zhong Y, Yang J, Xu WW, Wang Y, Zheng CC, Li B, He QY
Oncogene 2017 Nov 2;36(44):6177-6189

The role of the ATM/Chk/P53 pathway in mediating DNA damage in hand-foot syndrome induced by PLD.

Yang J, Qiao L, Zeng Z, Wang J, Zhu T, Wei J, Wu M, Ye S, Huang X, Ma D, Liu R, Gao Q
Toxicology letters 2017 Jan 4;265:131-139

Enterovirus 71 mediates cell cycle arrest in S phase through non-structural protein 3D.

Yu J, Zhang L, Ren P, Zhong T, Li Z, Wang Z, Li J, Liu X, Zhao K, Zhang W, Yu XF
Cell cycle (Georgetown, Tex.) 2015;14(3):425-36

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