Antibody data
- Antibody Data
- Antigen structure
- References [44]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 66391-1-Ig - Provider product page

- Provider
- Proteintech Group
- Product name
- Cyclin A2 antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated Cyclin A2 antibody (Cat. #66391-1-Ig) is a mouse monoclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1C6C11
- Vial size
- 20ul, 150ul
Submitted references Marine trichodermamide B inhibits prostate cancer progression via catalase inhibition-induced apoptosis.
SORBS1 Knockdown Resists S/G2 Arrest and Apoptosis Caused by Polyphyllin H-Induced DNA Damage in Pancreatic Cancer.
FAM50A as a novel prognostic marker modulates the proliferation of colorectal cancer cells via CylinA2/CDK2 pathway.
Temporal control of human DNA replication licensing by CDK4/6-RB signalling and chemical genetics.
TIM-3 Promotes Proliferation of Acute Myeloid Leukemia Blasts.
Kaempferol targets Src to exert its chemopreventive effects on mammary tumorigenesis via regulation of the PI3K/AKT pathway.
Annexin A2: regulating glioma's fate and a potential therapeutic target.
Ilicicolin C suppresses the progression of prostate cancer by inhibiting PI3K/AKT/mTOR pathway.
Reduced OTUD7B expression correlates with poor prognosis in PTCL via non-canonical NF-κB.
Carfilzomib inhibits the progression of hepatocellular cancer by upregulating GADD45α expression.
Exploring Potential Biomarkers and Molecular Mechanisms of Cutaneous Squamous Cell Carcinoma Based on Bioinformatics.
Cross-border regulation of the STK39/MAPK14 pathway by Lycium barbarum miR166a to inhibit triple-negative breast cancer.
Apolipoprotein L3 inhibits breast cancer proliferation and modulates cell cycle via the P53 pathway.
Integrative analysis of the transcriptome and metabolome reveals the importance of hepatokine FGF21 in liver aging.
Transient splicing inhibition causes persistent DNA damage and chemotherapy vulnerability in triple-negative breast cancer.
Comparison of the Mitotic Count With Various Proliferative Markers for the Effective Differentiation of Benign, Borderline, and Malignant Phyllodes Tumors.
STIM1 translocation to the nucleus protects cells from DNA damage.
Novel Dihydropteridinone Derivatives As Potent Inhibitors of the Understudied Human Kinases Vaccinia-Related Kinase 1 and Casein Kinase 1δ/ε.
Combined untargeted metabolomics and network pharmacology approaches to reveal the therapeutic role of withanolide B in psoriasis.
Adipocyte-Derived Exosomal NOX4-Mediated Oxidative Damage Induces Premature Placental Senescence in Obese Pregnancy.
Upregulation of HCFC1 expression promoted hepatocellular carcinoma progression through inhibiting cell cycle arrest and correlated with immune infiltration.
Osteogenic microenvironment affects palatal development through glycolysis.
The HNF4A-CHPF pathway promotes proliferation and invasion through interactions with MAD1L1 in glioma.
A Potential Anti-Glioblastoma Compound LH20 Induces Apoptosis and Arrest of Human Glioblastoma Cells via CDK4/6 Inhibition.
Downregulation of miR‑7 and miR‑153 is involved in Helicobacter pylori CagA induced gastric carcinogenesis and progression.
NUCKS1 promotes the progression of colorectal cancer via activating PI3K/AKT/mTOR signaling pathway.
Paradol Induces Cell Cycle Arrest and Apoptosis in Glioblastoma Cells.
Alpha1B-adreneroceptor is involved in norepinephrine-induced pulmonary artery smooth muscle cell proliferation via p38 signaling.
In vitro and in vivo anti-lymphoma effects of Ophiorrhiza pumila extract.
METTL3 promotes homologous recombination repair and modulates chemotherapeutic response in breast cancer by regulating the EGF/RAD51 axis.
HDAC7 promotes NSCLC proliferation and metastasis via stabilization by deubiquitinase USP10 and activation of β-catenin-FGF18 pathway.
Role of ferroptosis-related genes in coronary atherosclerosis and identification of key genes: integration of bioinformatics analysis and experimental validation.
Hsa_circ_0005050 interacts with ILF3 and affects cell apoptosis and proliferation by disrupting the balance between p53 and p65.
Cannabisin D from Sinomenium Acutum Inhibits Proliferation and Migration of Glioblastoma Cells through MAPKs Signaling.
Combined Treatment of Cinobufotalin and Gefitinib Exhibits Potent Efficacy against Lung Cancer.
ND‑09 inhibits chronic myeloid leukemia K562 cell growth by regulating BCR‑ABL signaling.
NT5DC2 promotes leiomyosarcoma tumour cell growth via stabilizing unpalmitoylated TEAD4 and generating a positive feedback loop.
Triptolidenol, isolated from Tripterygium wilfordii, disrupted NF-κB/COX-2 pathway by targeting ATP-binding sites of IKKβ in clear cell renal cell carcinoma.
Cell division cycle associated 8: A novel diagnostic and prognostic biomarker for hepatocellular carcinoma.
Cell cycle regulation of ER membrane biogenesis protects against chromosome missegregation.
A Mechanism of Action Study on Danggui Sini Decoction to Discover Its Therapeutic Effect on Gastric Cancer.
KCTD12 promotes tumorigenesis by facilitating CDC25B/CDK1/Aurora A-dependent G2/M transition.
The role of the ATM/Chk/P53 pathway in mediating DNA damage in hand-foot syndrome induced by PLD.
Enterovirus 71 mediates cell cycle arrest in S phase through non-structural protein 3D.
Fang W, Chen C, Nie M, Liu Q, Huang T, Gao C, Liu Y, Zhou X, Wang X
Cell communication and signaling : CCS 2026 Feb 16;24(1)
Cell communication and signaling : CCS 2026 Feb 16;24(1)
SORBS1 Knockdown Resists S/G2 Arrest and Apoptosis Caused by Polyphyllin H-Induced DNA Damage in Pancreatic Cancer.
Hu X, Xue Y, Fang F, Li J, Yuan X, Cheng G, Yuan H, Zhang Y, Zhou Y, Yang S, Qiu P, Lu Y, Tang H
Oncology research 2025;33(9):2491-2506
Oncology research 2025;33(9):2491-2506
FAM50A as a novel prognostic marker modulates the proliferation of colorectal cancer cells via CylinA2/CDK2 pathway.
Li L, Ji Z, Li G, Gu H, Sun Y
PloS one 2025;20(2):e0318776
PloS one 2025;20(2):e0318776
Temporal control of human DNA replication licensing by CDK4/6-RB signalling and chemical genetics.
Sosenko Piscitello A, Nilsson AS, Hawgood M, Sayyid AH, Dionellis VS, Giglio G, Urién B, Bajgain P, Ntallis SG, Bartek J, Halazonetis TD, Lemmens B
Nature communications 2025 Sep 12;16(1):8268
Nature communications 2025 Sep 12;16(1):8268
TIM-3 Promotes Proliferation of Acute Myeloid Leukemia Blasts.
Shi ZY, Sun K, Li ZY, Xie DH, Qin YZ
Biomedicines 2025 Nov 20;13(11)
Biomedicines 2025 Nov 20;13(11)
Kaempferol targets Src to exert its chemopreventive effects on mammary tumorigenesis via regulation of the PI3K/AKT pathway.
Wang P, Ma Y, Rao X, Luo Q, Xiao X, Wang T, Long F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156701
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156701
Annexin A2: regulating glioma's fate and a potential therapeutic target.
Liu W, Zhao X, Regmi M, Shamsutdinova MI, Shamsutdinov M, Liu S, Dai Y, Wang Y, Liu H, Wu J, Yang J, Yang C, Sino-Uzbek Regenerative Therapy Consortium (SURE)
Medical oncology (Northwood, London, England) 2025 Jul 28;42(9):386
Medical oncology (Northwood, London, England) 2025 Jul 28;42(9):386
Ilicicolin C suppresses the progression of prostate cancer by inhibiting PI3K/AKT/mTOR pathway.
Gan X, Luo X, Chen J, Fang W, Nie M, Lu H, Liu Y, Wang X
Molecular and cellular biochemistry 2025 Feb;480(2):1089-1104
Molecular and cellular biochemistry 2025 Feb;480(2):1089-1104
Reduced OTUD7B expression correlates with poor prognosis in PTCL via non-canonical NF-κB.
Chen F, Qiu S, Gui A, Jiang S, Yan Y, Wu J, Chen G, Zhu S, Liu Y, Xia Z, Yu B, Sun X, Gu JJ, Wang L, Liu W, Yang L, Zhang Q, Zuo J
International journal of hematology 2025 Feb;121(2):194-205
International journal of hematology 2025 Feb;121(2):194-205
Carfilzomib inhibits the progression of hepatocellular cancer by upregulating GADD45α expression.
Chen M, Chen X, Shui Y, Ji C, Guo W
Oncology letters 2025 Apr;29(4):208
Oncology letters 2025 Apr;29(4):208
Exploring Potential Biomarkers and Molecular Mechanisms of Cutaneous Squamous Cell Carcinoma Based on Bioinformatics.
Qi J, Guo Q, Bai J, Liang X, Zhu W, Li C, Xie F
OncoTargets and therapy 2024;17:841-856
OncoTargets and therapy 2024;17:841-856
Cross-border regulation of the STK39/MAPK14 pathway by Lycium barbarum miR166a to inhibit triple-negative breast cancer.
Hou Y, Li J, Li X, Lv Y, Yuan C, Tian J, Liu X
American journal of translational research 2024;16(6):2683-2698
American journal of translational research 2024;16(6):2683-2698
Apolipoprotein L3 inhibits breast cancer proliferation and modulates cell cycle via the P53 pathway.
Yu H, Li S, Li X, Liu Y, Wang Z, Cui M, Jin F, Yu X
Journal of Cancer 2024;15(14):4623-4635
Journal of Cancer 2024;15(14):4623-4635
Integrative analysis of the transcriptome and metabolome reveals the importance of hepatokine FGF21 in liver aging.
Wang W, Qian J, Shang M, Qiao Y, Huang J, Gao X, Ye Z, Tong X, Xu K, Li X, Liu Z, Zhou L, Zheng S
Genes & diseases 2024 Sep;11(5):101161
Genes & diseases 2024 Sep;11(5):101161
Transient splicing inhibition causes persistent DNA damage and chemotherapy vulnerability in triple-negative breast cancer.
Caggiano C, Petrera V, Ferri M, Pieraccioli M, Cesari E, Di Leone A, Sanchez MA, Fabi A, Masetti R, Naro C, Sette C
Cell reports 2024 Sep 24;43(9):114751
Cell reports 2024 Sep 24;43(9):114751
Comparison of the Mitotic Count With Various Proliferative Markers for the Effective Differentiation of Benign, Borderline, and Malignant Phyllodes Tumors.
Amaya K, Okimura A, Hirano H, Wakiya M, Hirai H, Nagao T, Ishikawa T, Yamada K, Nakatsugawa M
Cureus 2024 Oct;16(10):e71494
Cureus 2024 Oct;16(10):e71494
STIM1 translocation to the nucleus protects cells from DNA damage.
Sanchez-Lopez I, Orantos-Aguilera Y, Pozo-Guisado E, Alvarez-Barrientos A, Lilla S, Zanivan S, Lachaud C, Martin-Romero FJ
Nucleic acids research 2024 Mar 21;52(5):2389-2415
Nucleic acids research 2024 Mar 21;52(5):2389-2415
Novel Dihydropteridinone Derivatives As Potent Inhibitors of the Understudied Human Kinases Vaccinia-Related Kinase 1 and Casein Kinase 1δ/ε.
de Souza Gama FH, Dutra LA, Hawgood M, Dos Reis CV, Serafim RAM, Ferreira MA Jr, Teodoro BVM, Takarada JE, Santiago AS, Balourdas DI, Nilsson AS, Urien B, Almeida VM, Gileadi C, Ramos PZ, Salmazo A, Vasconcelos SNS, Cunha MR, Mueller S, Knapp S, Massirer KB, Elkins JM, Gileadi O, Mascarello A, Lemmens BBLG, Guimarães CRW, Azevedo H, Couñago RM
Journal of medicinal chemistry 2024 Jun 13;67(11):8609-8629
Journal of medicinal chemistry 2024 Jun 13;67(11):8609-8629
Combined untargeted metabolomics and network pharmacology approaches to reveal the therapeutic role of withanolide B in psoriasis.
Li T, Gao S, Wei Y, Wu G, Feng Y, Wang Y, Jiang X, Kuang H, Han W
Journal of pharmaceutical and biomedical analysis 2024 Aug 1;245:116163
Journal of pharmaceutical and biomedical analysis 2024 Aug 1;245:116163
Adipocyte-Derived Exosomal NOX4-Mediated Oxidative Damage Induces Premature Placental Senescence in Obese Pregnancy.
Tao Y, Chen W, Xu H, Xu J, Yang H, Luo X, Chen M, He J, Bai Y, Qi H
International journal of nanomedicine 2023;18:4705-4726
International journal of nanomedicine 2023;18:4705-4726
Upregulation of HCFC1 expression promoted hepatocellular carcinoma progression through inhibiting cell cycle arrest and correlated with immune infiltration.
Wang H, Yu M, Yang C, Li Q
Journal of Cancer 2023;14(8):1381-1397
Journal of Cancer 2023;14(8):1381-1397
Osteogenic microenvironment affects palatal development through glycolysis.
Peng X, Chen J, Wang Y, Wang X, Zhao X, Zheng X, Wang Z, Yuan D, Du J
Differentiation; research in biological diversity 2023 Sep-Oct;133:1-11
Differentiation; research in biological diversity 2023 Sep-Oct;133:1-11
The HNF4A-CHPF pathway promotes proliferation and invasion through interactions with MAD1L1 in glioma.
Luo H, Huang K, Cheng M, Long X, Zhu X, Wu M
Aging 2023 Oct 17;15(20):11052-11066
Aging 2023 Oct 17;15(20):11052-11066
A Potential Anti-Glioblastoma Compound LH20 Induces Apoptosis and Arrest of Human Glioblastoma Cells via CDK4/6 Inhibition.
Wang Y, Li Y, Liu D, Zheng D, Li X, Li C, Huang C, Wang Y, Wang X, Li Q, Xu J
Molecules (Basel, Switzerland) 2023 Jun 28;28(13)
Molecules (Basel, Switzerland) 2023 Jun 28;28(13)
Downregulation of miR‑7 and miR‑153 is involved in Helicobacter pylori CagA induced gastric carcinogenesis and progression.
Song Y, Guo D, Liu JF, Ge LN, Liu P, Qu YM, Cong HY, Li T, Chang X, Wang YR, Shao LY, Du ZJ, Wang MY
International journal of oncology 2023 Jul;63(1)
International journal of oncology 2023 Jul;63(1)
NUCKS1 promotes the progression of colorectal cancer via activating PI3K/AKT/mTOR signaling pathway.
Zhu LL, Shi JJ, Guo YD, Yang C, Wang RL, Li SS, Gan DX, Ma PX, Li JQ, Su HC
Neoplasma 2023 Apr;70(2):272-286
Neoplasma 2023 Apr;70(2):272-286
Paradol Induces Cell Cycle Arrest and Apoptosis in Glioblastoma Cells.
Wang R, Liu T, Chen J, Zhang D
Nutrition and cancer 2022;74(8):3007-3014
Nutrition and cancer 2022;74(8):3007-3014
Alpha1B-adreneroceptor is involved in norepinephrine-induced pulmonary artery smooth muscle cell proliferation via p38 signaling.
Xiao X, Zhang Y, Tian S, Wang X, Zhang Q, Zhang L, Yu X, Ma C, Zheng X, Li Y, Zhang J, Qu L
European journal of pharmacology 2022 Sep 15;931:175159
European journal of pharmacology 2022 Sep 15;931:175159
In vitro and in vivo anti-lymphoma effects of Ophiorrhiza pumila extract.
Fan L, Liao W, Chen Z, Li S, Yang A, Chen MM, Liu H, Liu F
Aging 2022 May 3;14(9):3801-3812
Aging 2022 May 3;14(9):3801-3812
METTL3 promotes homologous recombination repair and modulates chemotherapeutic response in breast cancer by regulating the EGF/RAD51 axis.
Li E, Xia M, Du Y, Long K, Ji F, Pan F, He L, Hu Z, Guo Z
eLife 2022 May 3;11
eLife 2022 May 3;11
HDAC7 promotes NSCLC proliferation and metastasis via stabilization by deubiquitinase USP10 and activation of β-catenin-FGF18 pathway.
Guo K, Ma Z, Zhang Y, Han L, Shao C, Feng Y, Gao F, Di S, Zhang Z, Zhang J, Tabbò F, Ekman S, Suda K, Cappuzzo F, Han J, Li X, Yan X
Journal of experimental & clinical cancer research : CR 2022 Mar 11;41(1):91
Journal of experimental & clinical cancer research : CR 2022 Mar 11;41(1):91
Role of ferroptosis-related genes in coronary atherosclerosis and identification of key genes: integration of bioinformatics analysis and experimental validation.
Meng Q, Xu Y, Ling X, Liu H, Ding S, Wu H, Yan D, Fang X, Li T, Liu Q
BMC cardiovascular disorders 2022 Jul 29;22(1):339
BMC cardiovascular disorders 2022 Jul 29;22(1):339
Hsa_circ_0005050 interacts with ILF3 and affects cell apoptosis and proliferation by disrupting the balance between p53 and p65.
Tan J, Sun M, Yin J, Zhou Q, Zhao R, Chen Q, Sun H, Jiang C, Li S, He Y
Chemico-biological interactions 2022 Dec 1;368:110208
Chemico-biological interactions 2022 Dec 1;368:110208
Cannabisin D from Sinomenium Acutum Inhibits Proliferation and Migration of Glioblastoma Cells through MAPKs Signaling.
Zhang D, Li C, Zhang L, Li B, Wang Y, Wang R, Chen Z, Xu L, Liu T
Nutrition and cancer 2021;73(11-12):2491-2501
Nutrition and cancer 2021;73(11-12):2491-2501
Combined Treatment of Cinobufotalin and Gefitinib Exhibits Potent Efficacy against Lung Cancer.
Han Y, Ma R, Cao G, Liu H, He L, Tang L, Li H, Luo Q
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6612365
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6612365
ND‑09 inhibits chronic myeloid leukemia K562 cell growth by regulating BCR‑ABL signaling.
Liu YH, Zhu M, Lei PP, Pan XY, Ma WN
Oncology reports 2021 Jul;46(1)
Oncology reports 2021 Jul;46(1)
NT5DC2 promotes leiomyosarcoma tumour cell growth via stabilizing unpalmitoylated TEAD4 and generating a positive feedback loop.
Hu B, Zhou S, Hu X, Zhang H, Lan X, Li M, Wang Y, Hu Q
Journal of cellular and molecular medicine 2021 Jul;25(13):5976-5987
Journal of cellular and molecular medicine 2021 Jul;25(13):5976-5987
Triptolidenol, isolated from Tripterygium wilfordii, disrupted NF-κB/COX-2 pathway by targeting ATP-binding sites of IKKβ in clear cell renal cell carcinoma.
Jin J, Zhou M, Wang X, Liu M, Huang H, Yan F, Yu Z, Shu X, Huo X, Feng L, Zhang B, Huang S, Deng S, Wang C, Ma X
Fitoterapia 2021 Jan;148:104779
Fitoterapia 2021 Jan;148:104779
Cell division cycle associated 8: A novel diagnostic and prognostic biomarker for hepatocellular carcinoma.
Cui XH, Peng QJ, Li RZ, Lyu XJ, Zhu CF, Qin XH
Journal of cellular and molecular medicine 2021 Dec;25(24):11097-11112
Journal of cellular and molecular medicine 2021 Dec;25(24):11097-11112
Cell cycle regulation of ER membrane biogenesis protects against chromosome missegregation.
Merta H, Carrasquillo Rodríguez JW, Anjur-Dietrich MI, Vitale T, Granade ME, Harris TE, Needleman DJ, Bahmanyar S
Developmental cell 2021 Dec 20;56(24):3364-3379.e10
Developmental cell 2021 Dec 20;56(24):3364-3379.e10
A Mechanism of Action Study on Danggui Sini Decoction to Discover Its Therapeutic Effect on Gastric Cancer.
Pan B, Wang Y, Wu C, Jia J, Huang C, Fang S, Liu L
Frontiers in pharmacology 2020;11:592903
Frontiers in pharmacology 2020;11:592903
KCTD12 promotes tumorigenesis by facilitating CDC25B/CDK1/Aurora A-dependent G2/M transition.
Zhong Y, Yang J, Xu WW, Wang Y, Zheng CC, Li B, He QY
Oncogene 2017 Nov 2;36(44):6177-6189
Oncogene 2017 Nov 2;36(44):6177-6189
The role of the ATM/Chk/P53 pathway in mediating DNA damage in hand-foot syndrome induced by PLD.
Yang J, Qiao L, Zeng Z, Wang J, Zhu T, Wei J, Wu M, Ye S, Huang X, Ma D, Liu R, Gao Q
Toxicology letters 2017 Jan 4;265:131-139
Toxicology letters 2017 Jan 4;265:131-139
Enterovirus 71 mediates cell cycle arrest in S phase through non-structural protein 3D.
Yu J, Zhang L, Ren P, Zhong T, Li Z, Wang Z, Li J, Liu X, Zhao K, Zhang W, Yu XF
Cell cycle (Georgetown, Tex.) 2015;14(3):425-36
Cell cycle (Georgetown, Tex.) 2015;14(3):425-36
No comments: Submit comment
No validations: Submit validation data