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Learn10493-1-AP
antibody from Proteintech Group
Targeting: TAGLN
DKFZp686P11128, SM22, SMCC, TAGLN1, WS3-10
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ELISAAntibody data
- Antibody Data
- Antigen structure
- References [201]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 10493-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10493-1-AP, RRID:AB_2199363
- Product name
- transgelin/SM22 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated transgelin/SM22 antibody (Cat. #10493-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Arachidonic Acid-Induced Contraction of Smooth Muscle Is Mediated by MLC Phosphorylation in Preterm Birth.
Construction and validation of a novel diagnostic model for esophageal squamous cell carcinoma: an integrated analysis of multi-omics data.
SERCA2 dysfunction drives vascular calcification via coupling with TSPO-MCU at mitochondria-associated endoplasmic reticulum membranes.
Xuefu Zhuyu decoction attenuates thoracic aortic dissection by regulating VSMC phenotypic switching and oxidative stress via the JAK2/STAT3/HIF-1α pathway.
Single-Cell Multimodal Profiling Highlights Persistent Aortic Smooth Muscle Cell Changes in Diabetic Mice Despite Glycemic Control.
Safeguarding VSMC Contractile Phenotype With In Situ circRNA-mediated Endothelial Olaratumab Engineering to Prevent Vascular Graft Stenosis.
ZNF384-Driven Fibulin-1 Exacerbates Vascular Stiffness via TGF-β/Smad3-Mediated Senescence and Fibrosis.
Microenvironment-activatable nanoagent for real-time NIR-II monitoring and targeted therapy of arterial restenosis.
Complement C3/C3a-CCL9 feedback loop orchestrates inflammatory crosstalk to accelerate aortic dissection.
Mechanical stress accelerates vascular calcification by Piezo1/BMP2 of vascular smooth muscle cells.
Selenomethionine alleviates aortic dissection via PGC-1α/NRF2/TFAM-mediated mitochondrial biosynthesis against ferroptosis: an experimental study.
Lactate Promotes Endothelial-Mesenchymal Transition via Mediating Twist1 Lactylation in Hypoxic Pulmonary Hypertension.
Engineered extracellular vesicles from human placental mesenchymal stem cells attenuate abdominal aortic aneurysm formation by inhibiting Nat10-mediated vascular smooth muscle cell senescence.
Fosb promotes ferroptosis in vascular smooth muscle cells via the NF-κB pathway to exacerbate abdominal aortic aneurysm progression.
Apolipoprotein C3 exacerbates vascular calcification by promoting ferroptosis via the TLR2/AMPK pathway in vascular smooth muscle cells.
Subamnex Ameliorates Hypoxia-Induced Pulmonary Arterial Hypertension through Modulation of the STAT3/p-STAT3 Pathway.
Buyang Huanwu Decoction suppresses atherosclerosis by targeting IFITM1‑mediated lipid metabolism in vascular smooth muscle cells.
Knockdown of GBP5 Attenuates Abdominal Aortic Aneurysm Formation via the NF-κB Pathway.
Endothelial TIE2 Mutation Induced Contraction Deficiency of Vascular Smooth Muscle Cells via Phenotypic Transition Regulation in Venous Malformations.
TAGLN-RhoA/ROCK2-SLC2A3-mediated Mechano-metabolic Axis Promotes Skin Fibrosis.
The lncRNA SENCR knockdown alleviates vascular calcification via miR-4731-5p by suppressing endoplasmic reticulum stress.
Notch dimerization provides robustness against environmental insults and is required for vascular integrity.
Melk facilitates pulmonary artery smooth muscle cell proliferation and migration in pulmonary hypertension via modulation of YAP/TAZ signaling.
SOX9 mediates the phenotypic transformation of vascular smooth muscle cells in restenosis after carotid artery injury.
Injury and cyclic stretch induce vein graft failure: effective treatment with zinc oxide-loaded electrospun polycaprolactone external stent.
IFITM1 promotes proliferation, migration and macrophage-like transdifferentiation of vascular smooth muscle cells via c-Src/MAPK/GATA2/E2F2 pathway in atherosclerosis.
Insufficient BK channel function enhances NF-κB nuclear translocation and promotes IL-6 synthesis in vascular smooth muscle cells induced by AT1-AA.
Macropinocytosis maintains CAF subtype identity under metabolic stress in pancreatic cancer.
Mechanism of ferroptosis in hypoxia-induced pulmonary vascular remodeling in hypoxia pulmonary hypertension: a study based on the ACE2-Ang-(1-7)-Mas axis.
GALNT4 controls aortic dissection by regulating vascular smooth muscle cell phenotype switch and dysfunction through the TGF-β/smad signaling.
Identification of lactylation-related hub genes as novel therapeutic and diagnostic targets for thoracic aortic dissection.
EphrinB2 in dental pulp stem cells promotes endothelial cells forming capillary-like cords in a 3D bioprinted hydrogel construct.
LncRNA SNHG8 promotes myocardial fibrosis by binding to E2F1 to induce MAD2L1 transcription.
MYST1-Mediated Lysine Acetylation Stabilizes KLF4 to Promote Intimal Hyperplasia.
Genetic background and transient prenatal disruption of vitamin A signaling determine susceptibility to airway hyperresponsiveness in mice.
Vasostatin-2 attenuates injury-induced neointimal hyperplasia through the ACE2/MasR/PPARγ/NR1D1/Gas1 axis.
NAT10 induces N4-acetylcytidine modification of AdipoR1-mediated mitochondrial biogenesis against endothelial-to-mesenchymal transition in hypertension.
Berberine ameliorates atherosclerosis by inhibiting the phenotypic transition of vascular smooth muscle cells via suppression of the JAK2/STAT3 signaling pathway.
eIF4A1 exacerbates myocardial ischemia-reperfusion injury in mice by promoting nuclear translocation of transgelin/p53.
PIASy deficiency mitigates thoracic aortic aneurysm formation via the TGF-β/Smad2/3 pathway.
Serum-free endothelial cell culture medium for vascular smooth muscle cells sheet formation.
Orai1 Participates in Coronary Artery Dysfunction Caused by Hypertension via Regulating Smooth Muscle Cell Phenotype Transformation.
Urolithin B suppresses phenotypic switch in vascular smooth muscle cells induced by PDGF-BB via inhibiting the PI3K-AKT pathway.
Enhanced Vascular Smooth Muscle Cell and Extracellular Matrix Repair Using a Metal-Organic Framework-Based Co-Delivery System for Abdominal Aortic Aneurysm Therapy.
Marrow adipogenic lineage precursors (MALPs) facilitate bone marrow recovery after chemotherapy.
The single-cell transcription reveals the aberrant differentiation trajectory of chondrocytes in the intervertebral disc for congenital scoliosis.
The upregulation of TNKS1 drives the phenotypic switching of vascular smooth muscle cells in aortic dissection through the activation of ferroptosis.
The Piezo1/Extracellular Signal-Regulated Kinase Signal Pathway Regulates Proliferation and Migration of Aortic Vascular Smooth Muscle Cells and Participates in Thoracic Aortic Aneurysm.
Cytoplasmic and nuclear NFATc3 cooperatively contributes to vascular smooth muscle cell dysfunction and drives aortic aneurysm and dissection.
Piezo1 promotes vibration-induced vascular smooth muscle injury by regulating the NF-κB/p65 axis.
Uncovering endothelial to mesenchymal transition drivers in atherosclerosis via multi-omics analysis.
High Shear Stress-Induced Endothelial Piezo1 Downregulation Promotes Intracranial Aneurysm Formation via the PDGF-BB/PDGFRβ Paracrine Signaling Pathway.
The Mechanism of Matrilin-2 Inhibiting the Progression of In-Stent Restenosis for Lower Extremity Arteriosclerosis Obliterans via TGF-β/Smad Signaling Pathway.
TAGLN: a stiffness-driven prognostic biomarker for metastatic colorectal cancer.
Distinct populations of vascular smooth muscle and sinoatrial progenitors are localized adjacent to pro-epicardium.
Heterogeneity of common carotid artery and abdominal aorta: an angle of sphingolipid metabolism in vascular smooth muscle cells.
Agathis dammara Extract and its Monomer Araucarone Attenuate Abdominal Aortic Aneurysm in Mice.
Isovaleroylbinankadsurin A ameliorates atherosclerosis and restenosis by promoting LXRα signaling pathway and inhibiting TGF-β1 and FHL1 signaling pathways.
Analysis of the pathogenicity and pathological characteristics of NOTCH3 gene-sparing cysteine mutations in vitro and in vivo models.
Establishment and evaluation of a carotid artery dissection model in rats.
GSDMB involvement in the pathogenesis of abdominal aortic aneurysm through regulation of macrophage non-canonical pyroptosis.
STING1-accelerated vascular smooth muscle cell senescence-associated vascular calcification in diabetes is ameliorated by oleoylethanolamide via improved mitochondrial DNA oxidative damage.
Tudor-SN exacerbates pathological vascular remodeling by promoting the polyubiquitination of PTEN via NEDD4-1.
Insulin-transferrin-selenium promote formation of tissue-engineered vascular grafts in early stage of culture.
The protective mechanism of sevoflurane in pulmonary arterial hypertension via downregulation of TRAF6.
Potential of dapagliflozin to prevent vascular remodeling in the rat carotid artery following balloon injury.
CircLMBR1 inhibits phenotypic transformation of hypoxia-induced pulmonary artery smooth muscle via the splicing factor PUF60.
Construction of competitive endogenous RNA network and identification of potential regulatory axis in vascular calcification.
Irisin suppresses PDGF-BB-induced proliferation of vascular smooth muscle cells in vitro by activating AMPK/mTOR-mediated autophagy.
Nesfatin-1 enhances vascular smooth muscle calcification through facilitating BMP-2 osteogenic signaling.
Early growth response 1 exacerbates thoracic aortic aneurysm and dissection of mice by inducing the phenotypic switching of vascular smooth muscle cell through the activation of Krüppel-like factor 5.
Lutein protects senescent ciliary muscle against oxidative stress through the Keap1/Nrf2/ARE pathway.
High relative humidity environment alleviates hypoxia-induced pulmonary arterial hypertension in mice.
TRIM65 promotes vascular smooth muscle cell phenotypic transformation by activating PI3K/Akt/mTOR signaling during atherogenesis.
Knockdown of ARHGAP24 reduces intimal hyperplasia through inhibiting the proliferation and phenotypic switching of smooth muscle cells possibly by inactivating both AKT and ERK1/2 signaling pathways.
Single-cell assessment of primary and stem cell-derived human trophoblast organoids as placenta-modeling platforms.
Fibulin 1, targeted by microRNA-24-3p, promotes cell proliferation and migration in vascular smooth muscle cells, contributing to the development of atherosclerosis in APOE(-/-) mice.
Targeting deubiquitinase OTUB1 protects vascular smooth muscle cells in atherosclerosis by modulating PDGFRβ.
High estrogen induces trans-differentiation of vascular smooth muscle cells to a macrophage-like phenotype resulting in aortic inflammation via inhibiting VHL/HIF1a/KLF4 axis.
Biphasic regulation of miR-17∼92 transcription during hypoxia: roles of HIF1 and p53 hyperphosphorylation at ser15.
68Ga-FAPI PET imaging monitors response to combined TGF-βR inhibition and immunotherapy in metastatic colorectal cancer.
C1q/tumor necrosis factor-related protein-6 suppresses the angiotensin II-induced differentiation of cardiac fibroblasts to myofibroblasts via activation of the AMPK pathway.
Histone deacetylase 9 promotes osteogenic trans-differentiation of vascular smooth muscle cells via ferroptosis in chronic kidney disease vascular calcification.
Effects of soluble Klotho and Wnt/β-catenin signaling pathway in vascular calcification in chronic kidney disease model rats and the intervention of Shenyuan granules.
Advanced glycosylation end products promote the progression of CKD-MBD in rats, and its natural inhibitor, quercetin, mitigates disease progression.
Macropinocytosis controls metabolic stress-driven CAF subtype identity in pancreatic cancer.
miR-200a-3p-enriched MSC-derived extracellular vesicles reverse erectile function in diabetic rats by targeting Keap1.
M2 Macrophage-Derived Exosomes Inhibit Atherosclerosis Progression by Regulating the Proliferation, Migration, and Phenotypic Transformation of Smooth Muscle Cells.
Single-cell RNA-Seq reveals the heterogeneity of fibroblasts within the tympanojugular paraganglioma microenvironment.
Quinic acid regulated TMA/TMAO-related lipid metabolism and vascular endothelial function through gut microbiota to inhibit atherosclerotic.
Trimethylamine N-oxide Promotes Atherosclerosis by Regulating Low-Density Lipoprotein-Induced Autophagy in Vascular Smooth Muscle Cells Through PI3K/AKT/mTOR Pathway.
miR-145 Alleviates Smooth Muscle Cell Phenotype Transition via ADAM17-Mediated ACE2 Shedding.
DNMT1 mediates the disturbed flow-induced endothelial to mesenchymal transition through disrupting β-alanine and carnosine homeostasis.
S-propargyl-cysteine promotes the stability of atherosclerotic plaque via maintaining vascular muscle contractile phenotype.
MiR-21-3p in extracellular vesicles from vascular fibroblasts of spontaneously hypertensive rat promotes proliferation and migration of vascular smooth muscle cells.
Clearance of Stress-Induced Premature Senescent Cells Alleviates the Formation of Abdominal Aortic Aneurysms.
Asparagine endopeptidase protects podocytes in adriamycin-induced nephropathy by regulating actin dynamics through cleaving transgelin.
Interaction of TAGLN and USP1 promotes ZEB1 ubiquitination degradation in UV-induced skin photoaging.
TGF-β-induced PI3K/AKT/mTOR pathway controls myofibroblast differentiation and secretory phenotype of valvular interstitial cells through the modulation of cellular senescence in a naturally occurring in vitro canine model of myxomatous mitral valve disease.
Inflachromene inhibits intimal hyperplasia through the HMGB1/2- regulated TLR4-NF-κB pathway.
Tumor-Associated Fibroblast-Derived Exosomal circDennd1b Promotes Pituitary Adenoma Progression by Modulating the miR-145-5p/ONECUT2 Axis and Activating the MAPK Pathway.
A TEMPOL and rapamycin loaded nanofiber-covered stent favors endothelialization and mitigates neointimal hyperplasia and local inflammation.
PKR deficiency delays vascular aging via inhibiting GSDMD-mediated endothelial cell hyperactivation.
Oleoylethanolamide alleviates hyperlipidaemia-mediated vascular calcification via attenuating mitochondrial DNA stress triggered autophagy-dependent ferroptosis by activating PPARα.
Overexpression of LOX-1 in hepatocytes protects vascular smooth muscle cells from phenotype transformation and wire injury induced carotid neoatherosclerosis through ALOX15.
CDN1163 alleviates SERCA2 dysfunction-induced pulmonary vascular remodeling by inhibiting the phenotypic transition of pulmonary artery smooth muscle cells.
Axon guidance genes control hepatic artery development.
miR-342-5p promotes vascular smooth muscle cell phenotypic transition through a negative-feedback regulation of Notch signaling via targeting FOXO3.
Exosomes Derived from Endothelial Cells Inhibit Neointimal Hyperplasia Induced by Carotid Artery Injury in Rats via ROS-NLRP3 Inflammasome Pathway.
Fate mapping RNA-sequencing reveal Malat1 regulates Sca1(+) progenitor cells to vascular smooth muscle cells transition in vascular remodeling.
BRG1 is involved in vascular calcification in chronic renal disease via autophagy of vascular smooth muscle cells.
Network pharmacology and experimental analysis to reveal the mechanism of Dan-Shen-Yin against endothelial to mesenchymal transition in atherosclerosis.
Theaflavin-3,3'-Digallate from Black Tea Inhibits Neointima Formation Through Suppression of the PDGFRβ Pathway in Vascular Smooth Muscle Cells.
Stromal Fibroblasts Counteract the Caveolin-1-Dependent Radiation Response of LNCaP Prostate Carcinoma Cells.
Substitution of SERCA2 Cys(674) accelerates aortic aneurysm by inducing endoplasmic reticulum stress and promoting cell apoptosis.
Metabonomics profile analysis in inflammation-induced preterm birth and the potential role of metabolites in regulating premature cervical ripening.
Gut microbiome dysbiosis contributes to abdominal aortic aneurysm by promoting neutrophil extracellular trap formation.
Moxifloxacin induces aortic aneurysm and dissection by increasing osteopontin in mice.
The substitution of SERCA2 redox cysteine 674 promotes pulmonary vascular remodeling by activating IRE1α/XBP1s pathway.
miR-335-5p regulates the proliferation, migration and phenotypic switching of vascular smooth muscle cells in aortic dissection by directly regulating SP1.
Kv7.4 channel is a key regulator of vascular inflammation and remodeling in neointimal hyperplasia and abdominal aortic aneurysms.
SIRT6 protects vascular smooth muscle cells from osteogenic transdifferentiation via Runx2 in chronic kidney disease.
Ubiquitin-specific protease 47 is associated with vascular calcification in chronic kidney disease by regulating osteogenic transdifferentiation of vascular smooth muscle cells.
Sclerostin is involved in osteogenic transdifferentiation of vascular smooth muscle cells in chronic kidney disease-associated vascular calcification with non-canonical Wnt signaling.
Defective autophagy triggered by arterial cyclic stretch promotes neointimal hyperplasia in vein grafts via the p62/nrf2/slc7a11 signaling pathway.
Bempedoic acid, an ATP citrate lyase inhibitor, reduces intimal hyperplasia via activation of AMPKα signaling pathway.
Human Placental Endothelial Cell and Trophoblast Heterogeneity and Differentiation Revealed by Single-Cell RNA Sequencing.
Angiogenic factor AGGF1 blocks neointimal formation after vascular injury via interaction with integrin α7 on vascular smooth muscle cells.
Transient expansion and myofibroblast conversion of adipogenic lineage precursors mediate bone marrow repair after radiation.
MED12 Regulates Smooth Muscle Cell Functions and Participates in the Development of Aortic Dissection.
PRDX2 Protects Against Atherosclerosis by Regulating the Phenotype and Function of the Vascular Smooth Muscle Cell.
MicroRNA‑199a‑5p regulates FOXC2 to control human vascular smooth muscle cell phenotypic switch.
Angiotensin II-Induced Long Non-Coding RNA Alivec Regulates Chondrogenesis in Vascular Smooth Muscle Cells.
Targeting mitochondria-inflammation circle by renal denervation reduces atheroprone endothelial phenotypes and atherosclerosis.
Metformin attenuates hyperlipidaemia-associated vascular calcification through anti-ferroptotic effects.
TWIST1 induces phenotypic switching of vascular smooth muscle cells by downregulating p68 and microRNA-143/145.
Compound Danshen Dripping Pill inhibits doxorubicin or isoproterenol-induced cardiotoxicity.
Intermittent short-duration reoxygenation protects against simulated high altitude-induced pulmonary hypertension in rats.
Prostacyclin facilitates vascular smooth muscle cell phenotypic transformation via activating TP receptors when IP receptors are deficient.
Kaposi's sarcoma-associated herpesvirus vFLIP promotes MEndT to generate hybrid M/E state for tumorigenesis.
RETRACTED: The role of ATG-7 contributes to pulmonary hypertension by impacting vascular remodeling.
BGP-15 Inhibits Hyperglycemia-Aggravated VSMC Calcification Induced by High Phosphate.
The P2RY12 receptor promotes VSMC-derived foam cell formation by inhibiting autophagy in advanced atherosclerosis.
Hydrogen Sulfide Attenuates Aortic Remodeling in Aortic Dissection Associating with Moderated Inflammation and Oxidative Stress through a NO-Dependent Pathway.
MicroRNA-143-5p modulates pulmonary artery smooth muscle cells functions in hypoxic pulmonary hypertension through targeting HIF-1α.
Septin4 Prevents PDGF-BB-induced HAVSMC Phenotypic Transformation, Proliferation and Migration by Promoting SIRT1-STAT3 Deacetylation and Dephosphorylation.
Bioinformatics Analysis Reveals MicroRNA-193a-3p Regulates ACTG2 to Control Phenotype Switch in Human Vascular Smooth Muscle Cells.
Salvia miltiorrhiza-derived miRNAs suppress vascular remodeling through regulating OTUD7B/KLF4/NMHC IIA axis.
Paired box 9 regulates VSMC phenotypic transformation, proliferation, and migration via sonic hedgehog.
CTRP15 derived from cardiac myocytes attenuates TGFβ1-induced fibrotic response in cardiac fibroblasts.
Inhibition of vascular calcification by microRNA-155-5p is accompanied by the inactivation of TGF-β1/Smad2/3 signaling pathway.
miR-137 and its target T-type Ca(V) 3.1 channel modulate dedifferentiation and proliferation of cerebrovascular smooth muscle cells in simulated microgravity rats by regulating calcineurin/NFAT pathway.
T-cell death-associated gene 8 accelerates atherosclerosis by promoting vascular smooth muscle cell proliferation and migration.
Characterization of Burn Eschar Pericytes.
Mapping the Fine-Scale Organization and Plasticity of the Brain Vasculature.
WWP2 regulates SIRT1-STAT3 acetylation and phosphorylation involved in hypertensive angiopathy.
Icotinib Attenuates Monocrotaline-Induced Pulmonary Hypertension by Preventing Pulmonary Arterial Smooth Muscle Cell Dysfunction.
2,3,7,8-Tetrachlorodibenzo-p-dioxin promotes injury-induced vascular neointima formation in mice.
Reticulocalbin 2 enhances osteogenic differentiation of human vascular smooth muscle cells in diabetic conditions.
MicroRNA-122 promotes endothelial cell apoptosis by targeting XIAP: Therapeutic implication for atherosclerosis.
SPARC induces phenotypic modulation of human brain vascular smooth muscle cells via AMPK/mTOR-mediated autophagy.
Transactivation domain of Krüppel-like factor 15 negatively regulates angiotensin II-induced adventitial inflammation and fibrosis.
Poly(ADP-ribose) polymerase 1 accelerates vascular calcification by upregulating Runx2.
Death-associated protein kinase 3 deficiency alleviates vascular calcification via AMPK-mediated inhibition of endoplasmic reticulum stress.
Peroxisome Proliferator-Activated Receptor-γ Coactivator-1α Inhibits Vascular Calcification Through Sirtuin 3-Mediated Reduction of Mitochondrial Oxidative Stress.
Temporal and spatial changes of peroxiredoxin 2 levels in aortic media at very early stages of atherosclerotic lesion formation in apoE-knockout mice.
Salusin-β Promotes Vascular Calcification via Nicotinamide Adenine Dinucleotide Phosphate/Reactive Oxygen Species-Mediated Klotho Downregulation.
CTRP13 attenuates vascular calcification by regulating Runx2.
Ultramorphological analysis of plaque advancement and cholesterol crystal formation in Ldlr knockout mouse atherosclerosis.
Validation of Phosphodiesterase-10 as a Novel Target for Pulmonary Arterial Hypertension via Highly Selective and Subnanomolar Inhibitors.
Glucagon-Like Peptide-1 Mediates the Protective Effect of the Dipeptidyl Peptidase IV Inhibitor on Renal Fibrosis via Reducing the Phenotypic Conversion of Renal Microvascular Cells in Monocrotaline-Treated Rats.
Teniposide regulates the phenotype switching of vascular smooth muscle cells in a miR-21-dependent manner.
Chicoric acid prevents PDGF-BB-induced VSMC dedifferentiation, proliferation and migration by suppressing ROS/NFκB/mTOR/P70S6K signaling cascade.
Hyperlipidemia-induced cholesterol crystal production by endothelial cells promotes atherogenesis.
Targeting AGGF1 (angiogenic factor with G patch and FHA domains 1) for Blocking Neointimal Formation After Vascular Injury.
CD98 regulates vascular smooth muscle cell proliferation in atherosclerosis.
Progression-related loss of stromal Caveolin 1 levels fosters the growth of human PC3 xenografts and mediates radiation resistance.
MicroRNA-99a inhibits insulin-induced proliferation, migration, dedifferentiation, and rapamycin resistance of vascular smooth muscle cells by inhibiting insulin-like growth factor-1 receptor and mammalian target of rapamycin.
Vascular smooth muscle cell differentiation from human stem/progenitor cells.
Protein profile screening: reduced expression of Sord in the mouse epididymis induced by nicotine inhibits tyrosine phosphorylation level in capacitated spermatozoa.
C1q/tumor necrosis factor-related protein-6 attenuates post-infarct cardiac fibrosis by targeting RhoA/MRTF-A pathway and inhibiting myofibroblast differentiation.
Expression and significance of NELIN and SM22α in varicose vein tissue.
5-Aminolevulinic Acid-Mediated Sonodynamic Therapy Promotes Phenotypic Switching from Dedifferentiated to Differentiated Phenotype via Reactive Oxygen Species and p38 Mitogen-Activated Protein Kinase in Vascular Smooth Muscle Cells.
MicroRNA 302a is a novel modulator of cholesterol homeostasis and atherosclerosis.
CTRP3 attenuates post-infarct cardiac fibrosis by targeting Smad3 activation and inhibiting myofibroblast differentiation.
Increased Expression of Tissue/Salivary Transgelin mRNA Predicts Poor Prognosis in Patients with Oral Squamous Cell Carcinoma (OSCC).
Identification of colonic fibroblast secretomes reveals secretory factors regulating colon cancer cell proliferation.
Overexpression of c1q/tumor necrosis factor-related protein-3 promotes phosphate-induced vascular smooth muscle cell calcification both in vivo and in vitro.
Transgelin as a therapeutic target to prevent hypoxic pulmonary hypertension.
Transgelin overexpression in lung adenocarcinoma is associated with tumor progression.
Endothelial insulin-like growth factor-1 modulates proliferation and phenotype of smooth muscle cells induced by low shear stress.
Selenoprotein K is required for palmitoylation of CD36 in macrophages: implications in foam cell formation and atherogenesis.
Adrenomedullin attenuates vascular calcification in fructose-induced insulin resistance rats.
Upregulation of transgelin is an independent factor predictive of poor prognosis in patients with advanced pancreatic cancer.
Serum-free differentiation of functional human coronary-like vascular smooth muscle cells from embryonic stem cells.
ADAMTS-12 metalloprotease is necessary for normal inflammatory response.
Profiling of differentially expressed proteins in stage IV colorectal cancers with good and poor outcomes.
Directed differentiation of skin-derived precursors into functional vascular smooth muscle cells.
Peptide-mediated disruption of calmodulin-cyclin E interactions inhibits proliferation of vascular smooth muscle cells and neointima formation.
Up-regulation of two actin-associated proteins prompts pulmonary artery smooth muscle cell migration under hypoxia.
Dependence of proliferative vascular smooth muscle cells on CD98hc (4F2hc, SLC3A2).
Chen X, Chen J, Qiu J, Yan Y, Zhang R
Journal of pregnancy 2026;2026(1):e8266780
Journal of pregnancy 2026;2026(1):e8266780
Construction and validation of a novel diagnostic model for esophageal squamous cell carcinoma: an integrated analysis of multi-omics data.
Cui Y, Li S, Wu Z, Jin Y, Yu J, Chen Y, Chen J, Chang J, Yan Y, Li X, Li N, Hu S, Zhu C, Feng L
Frontiers in immunology 2026;17:1685902
Frontiers in immunology 2026;17:1685902
SERCA2 dysfunction drives vascular calcification via coupling with TSPO-MCU at mitochondria-associated endoplasmic reticulum membranes.
Pi S, Liu W, Zhao J, Chen H, Luo X, Wu S, Song J, Chen X, Li X, Luo W, Wang Y, Liu C, Ren J, Li T, Liu H, Tong X, Qin Z
Pharmacological research 2026 May;227:108177
Pharmacological research 2026 May;227:108177
Xuefu Zhuyu decoction attenuates thoracic aortic dissection by regulating VSMC phenotypic switching and oxidative stress via the JAK2/STAT3/HIF-1α pathway.
Cheng-Wen L, Rong G, Yi-Fan J, Shou-Jia W, Si-Yi L, Chun-Yan L, Fan L, Xiao-Qiang L, Wei-Xun D, Fan S
Journal of ethnopharmacology 2026 May 10;362:121324
Journal of ethnopharmacology 2026 May 10;362:121324
Single-Cell Multimodal Profiling Highlights Persistent Aortic Smooth Muscle Cell Changes in Diabetic Mice Despite Glycemic Control.
Tanwar VS, Malek V, Wang J, Luo Y, Malhi NK, Zhang H, Abdollahi M, Lanting L, Senapati P, Das S, Reddy MA, Zang C, Miller CL, Chen ZB, Natarajan R
Arteriosclerosis, thrombosis, and vascular biology 2026 Mar;46(3):e324012
Arteriosclerosis, thrombosis, and vascular biology 2026 Mar;46(3):e324012
Safeguarding VSMC Contractile Phenotype With In Situ circRNA-mediated Endothelial Olaratumab Engineering to Prevent Vascular Graft Stenosis.
Hu S, Ling S, Liang F, Pan Y, Wang J, Bao W, Zhu J, Wang F, Du Y, Cui W, Yin M
Advanced materials (Deerfield Beach, Fla.) 2026 Mar;38(17):e22615
Advanced materials (Deerfield Beach, Fla.) 2026 Mar;38(17):e22615
ZNF384-Driven Fibulin-1 Exacerbates Vascular Stiffness via TGF-β/Smad3-Mediated Senescence and Fibrosis.
Yan D, Ji T, Liang X, Luo M, Huang Y, Luo P, Yang Z, Zhang L, Li T, Bai YP, Zhang C, Ruan L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 31;40(6):e71599
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 31;40(6):e71599
Microenvironment-activatable nanoagent for real-time NIR-II monitoring and targeted therapy of arterial restenosis.
Meng X, Song J, Meng H, Liao C, Yin Z, Gong K, Kong D, Qi J, Duan Y
Biomaterials 2026 Jan;324:123482
Biomaterials 2026 Jan;324:123482
Complement C3/C3a-CCL9 feedback loop orchestrates inflammatory crosstalk to accelerate aortic dissection.
Zhong X, Li Y, Xie Y, Jiang H, Liu Z, Dong W, Wang H, Zeng H
Biochemical pharmacology 2026 Jan;243(Pt 1):117421
Biochemical pharmacology 2026 Jan;243(Pt 1):117421
Mechanical stress accelerates vascular calcification by Piezo1/BMP2 of vascular smooth muscle cells.
Li B, Zhao Z, Xia Y, Deng S, Chen X, Jiang N, Ke G, Wen S, Yuan Y, Wu Q, Tao Y, Chen B, Peng S, Huang W, Tang B, Hao W, Deng C, Liu S
Biochimica et biophysica acta. Molecular basis of disease 2026 Jan;1872(1):168061
Biochimica et biophysica acta. Molecular basis of disease 2026 Jan;1872(1):168061
Selenomethionine alleviates aortic dissection via PGC-1α/NRF2/TFAM-mediated mitochondrial biosynthesis against ferroptosis: an experimental study.
Lai S, Qin H, Wang X, Bi Y, Lai Z, Ji S, Guo W
International journal of surgery (London, England) 2026 Jan 1;112(1):553-569
International journal of surgery (London, England) 2026 Jan 1;112(1):553-569
Lactate Promotes Endothelial-Mesenchymal Transition via Mediating Twist1 Lactylation in Hypoxic Pulmonary Hypertension.
Li X, Wang F, Liu N, Liu Y, Yu W, Tang M
International journal of molecular sciences 2026 Feb 27;27(5)
International journal of molecular sciences 2026 Feb 27;27(5)
Engineered extracellular vesicles from human placental mesenchymal stem cells attenuate abdominal aortic aneurysm formation by inhibiting Nat10-mediated vascular smooth muscle cell senescence.
Jia X, Hu X, Fu Z, Zhang L, Luo X, Huang W, Hua Y, Fang Q, Zeng J, Huang F, Wei G, Bin J, Zheng H, Chen G, Huang S
Biomaterials 2026 Aug;331:124109
Biomaterials 2026 Aug;331:124109
Fosb promotes ferroptosis in vascular smooth muscle cells via the NF-κB pathway to exacerbate abdominal aortic aneurysm progression.
Li X, Wang Q, Zhang J, Zhao W, Zheng X
Cellular signalling 2026 Aug;144:112544
Cellular signalling 2026 Aug;144:112544
Apolipoprotein C3 exacerbates vascular calcification by promoting ferroptosis via the TLR2/AMPK pathway in vascular smooth muscle cells.
Zhou Z, Chen J, Wang H, Han Y, Liu C, Shen Q, Dong Z, Lu K, Zhai C, Xu Y, Zhang L, He L, Fang Y, Zhang L, Wang Y, Xian X, Yao L, Dong E, Huang W
Redox biology 2026 Apr;91:104088
Redox biology 2026 Apr;91:104088
Subamnex Ameliorates Hypoxia-Induced Pulmonary Arterial Hypertension through Modulation of the STAT3/p-STAT3 Pathway.
Ge RX, Shi JZ, Guo BH, Zhang MJ, Zeng M, An XR, Ye JS, Cheng G, Fan X, Wang MW, Zhou YF, Li X, Pang XB, Xie XM, Zhang HD, Zhao LL, He YY, Kou JJ, Ma J, Yan Y
Journal of medicinal chemistry 2026 Apr 23;69(8):8790-8806
Journal of medicinal chemistry 2026 Apr 23;69(8):8790-8806
Buyang Huanwu Decoction suppresses atherosclerosis by targeting IFITM1‑mediated lipid metabolism in vascular smooth muscle cells.
Huang Q, Tang X, Huang Q, Zhi S, Zheng X, Deng Q, Zhu J, Huang M, Pan Z, Hou J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr 20;156:158224
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr 20;156:158224
Knockdown of GBP5 Attenuates Abdominal Aortic Aneurysm Formation via the NF-κB Pathway.
Wang Y, Wang J, Chang Z
Applied biochemistry and biotechnology 2026 Apr 17;
Applied biochemistry and biotechnology 2026 Apr 17;
Endothelial TIE2 Mutation Induced Contraction Deficiency of Vascular Smooth Muscle Cells via Phenotypic Transition Regulation in Venous Malformations.
Du Z, Yu F, You YH, Zhao ZY, Tian ZW, Xiao M, Wang YA
International journal of medical sciences 2025;22(10):2518-2532
International journal of medical sciences 2025;22(10):2518-2532
TAGLN-RhoA/ROCK2-SLC2A3-mediated Mechano-metabolic Axis Promotes Skin Fibrosis.
Cheng X, Gao Z, Zhang J, Zheng H, Shan S, Zhou J
International journal of biological sciences 2025;21(2):658-670
International journal of biological sciences 2025;21(2):658-670
The lncRNA SENCR knockdown alleviates vascular calcification via miR-4731-5p by suppressing endoplasmic reticulum stress.
Huang Y, Zhan W, Song C, Tan M, Wu L, Wu S
PloS one 2025;20(5):e0323058
PloS one 2025;20(5):e0323058
Notch dimerization provides robustness against environmental insults and is required for vascular integrity.
Preusse K, Cochran K, Dai Q, Kopan R
PloS one 2025;20(1):e0311353
PloS one 2025;20(1):e0311353
Melk facilitates pulmonary artery smooth muscle cell proliferation and migration in pulmonary hypertension via modulation of YAP/TAZ signaling.
Yang Q, Chen P, He X, Jian J, He M, Lin T, Zheng S, Liu D
Frontiers in cell and developmental biology 2025;13:1693346
Frontiers in cell and developmental biology 2025;13:1693346
SOX9 mediates the phenotypic transformation of vascular smooth muscle cells in restenosis after carotid artery injury.
Jiang C, Ye J, Huang J, Gao Y, Chen H, Guo F, Guo L, Yuan X
Frontiers in cell and developmental biology 2025;13:1592594
Frontiers in cell and developmental biology 2025;13:1592594
Injury and cyclic stretch induce vein graft failure: effective treatment with zinc oxide-loaded electrospun polycaprolactone external stent.
Ma T, Tian W, Zhu F, Qi Y, Huang K
Regenerative biomaterials 2025;12:rbaf119
Regenerative biomaterials 2025;12:rbaf119
IFITM1 promotes proliferation, migration and macrophage-like transdifferentiation of vascular smooth muscle cells via c-Src/MAPK/GATA2/E2F2 pathway in atherosclerosis.
Huang QH, Tang XY, Huang QY, Zhi SB, Zheng XQ, Gan CY, Huang MF, Pan ZF, Zhong ZX
Biochemical pharmacology 2025 Sep;239:117014
Biochemical pharmacology 2025 Sep;239:117014
Insufficient BK channel function enhances NF-κB nuclear translocation and promotes IL-6 synthesis in vascular smooth muscle cells induced by AT1-AA.
Li Y, Xue L, Feng J, Wang Z, Long Y, Liu W, Zhang S, Zhi X, Hao H, Wang X, Liu H, Wang L
Biochemical pharmacology 2025 Sep;239:117000
Biochemical pharmacology 2025 Sep;239:117000
Macropinocytosis maintains CAF subtype identity under metabolic stress in pancreatic cancer.
Zhang Y, Ling L, Murad R, Maganti S, Manceau A, Hetrick HA, Neff M, Galapate CM, Grenier SF, Carrette F, Duong-Polk K, Bagchi A, Scott DA, Altman Y, Hope JL, Lowy AM, Bradley LM, Commisso C
Cancer cell 2025 Sep 8;43(9):1677-1696.e15
Cancer cell 2025 Sep 8;43(9):1677-1696.e15
Mechanism of ferroptosis in hypoxia-induced pulmonary vascular remodeling in hypoxia pulmonary hypertension: a study based on the ACE2-Ang-(1-7)-Mas axis.
Abudukeremu A, Aikemu A, Yang T, Fang L, Shanahati D, Nijiati Y
Chemico-biological interactions 2025 Sep 5;418:111596
Chemico-biological interactions 2025 Sep 5;418:111596
GALNT4 controls aortic dissection by regulating vascular smooth muscle cell phenotype switch and dysfunction through the TGF-β/smad signaling.
Guo L, Wei P, Zhou L, Han Z, Wang X, Li D
Biochimica et biophysica acta. Molecular basis of disease 2025 Oct;1871(7):167969
Biochimica et biophysica acta. Molecular basis of disease 2025 Oct;1871(7):167969
Identification of lactylation-related hub genes as novel therapeutic and diagnostic targets for thoracic aortic dissection.
Peng J, Jiang Z, Song J, Chen J, Fu Z, Zhang H, Zhen J, Tuerdi M, Luo M, Wu J, Sun T
Cellular signalling 2025 Oct;134:111944
Cellular signalling 2025 Oct;134:111944
EphrinB2 in dental pulp stem cells promotes endothelial cells forming capillary-like cords in a 3D bioprinted hydrogel construct.
Wang W, Li J, Zhou Y, Ren T, Yang Y, Li M, Tian H, Wang P, Yuan C
BMC molecular and cell biology 2025 Oct 29;26(1):33
BMC molecular and cell biology 2025 Oct 29;26(1):33
LncRNA SNHG8 promotes myocardial fibrosis by binding to E2F1 to induce MAD2L1 transcription.
Huang L, Liu C, Zhao Z, Xie S, Sun Z, Liao X, Bian X, Liu X, Ren X, Wang N
International journal of biological macromolecules 2025 Nov;331(Pt 1):148362
International journal of biological macromolecules 2025 Nov;331(Pt 1):148362
MYST1-Mediated Lysine Acetylation Stabilizes KLF4 to Promote Intimal Hyperplasia.
Wang S, Liu Z, Wen J, Zhang C, Wu F, Zeng Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Nov 30;39(22):e71247
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Nov 30;39(22):e71247
Genetic background and transient prenatal disruption of vitamin A signaling determine susceptibility to airway hyperresponsiveness in mice.
Otoshi T, Kameshwar AKS, Kotton BD, Seki Y, Cardell Z, Xiangyi K, Matsuno Y, Rajaram P, Kim YK, Sharpton SM, Quadro L, Cardoso WV, Suzuki M
bioRxiv : the preprint server for biology 2025 Nov 3;
bioRxiv : the preprint server for biology 2025 Nov 3;
Vasostatin-2 attenuates injury-induced neointimal hyperplasia through the ACE2/MasR/PPARγ/NR1D1/Gas1 axis.
Chen Q, Liu J, Madonna R, Li F, Chen S, Li L, Wu X, Maimati Y, Ding F, Wang X, Shen Y, Zhang R, Shen W, Dai Y, Lu L, De Caterina R
Cardiovascular research 2025 Nov 22;121(14):2260-2277
Cardiovascular research 2025 Nov 22;121(14):2260-2277
NAT10 induces N4-acetylcytidine modification of AdipoR1-mediated mitochondrial biogenesis against endothelial-to-mesenchymal transition in hypertension.
Pan H, Song L, Cheng Z, Zhu J, Zhou J, Xu Z, Zhang M
Molecular medicine (Cambridge, Mass.) 2025 Nov 18;31(1):332
Molecular medicine (Cambridge, Mass.) 2025 Nov 18;31(1):332
Berberine ameliorates atherosclerosis by inhibiting the phenotypic transition of vascular smooth muscle cells via suppression of the JAK2/STAT3 signaling pathway.
Zheng J, Wang T, Zhou Y, Chen Y, Shen X, Jin B, Han X, Hua C, Xie J
European journal of pharmacology 2025 Nov 15;1007:178234
European journal of pharmacology 2025 Nov 15;1007:178234
eIF4A1 exacerbates myocardial ischemia-reperfusion injury in mice by promoting nuclear translocation of transgelin/p53.
Li DY, Hu XX, Tian ZR, Ning QW, Liu JQ, Yue Y, Yuan W, Meng B, Li JL, Zhang Y, Pan ZW, Zhuang YT, Lu YJ
Acta pharmacologica Sinica 2025 May;46(5):1236-1249
Acta pharmacologica Sinica 2025 May;46(5):1236-1249
PIASy deficiency mitigates thoracic aortic aneurysm formation via the TGF-β/Smad2/3 pathway.
Shen D, Zheng H, Shao K, Zhu J, Hou Y, Ding Y
Journal of thoracic disease 2025 May 30;17(5):3400-3409
Journal of thoracic disease 2025 May 30;17(5):3400-3409
Serum-free endothelial cell culture medium for vascular smooth muscle cells sheet formation.
Yang J, Sun X, Jiang H, Li J, Liang J, Lin Z
Journal of biological engineering 2025 May 28;19(1):51
Journal of biological engineering 2025 May 28;19(1):51
Orai1 Participates in Coronary Artery Dysfunction Caused by Hypertension via Regulating Smooth Muscle Cell Phenotype Transformation.
Wang H, Liang MY, Cai YJ, Deng CY, Yang H, Mai LP, Zhang MZ, Kuang SJ, Rao F, Xu JS
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 15;39(9):e70576
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 15;39(9):e70576
Urolithin B suppresses phenotypic switch in vascular smooth muscle cells induced by PDGF-BB via inhibiting the PI3K-AKT pathway.
Li S, Zhang Y, Zhang T, Jiang D, Li M, Chen L, Jiang J, Zhang C, Li Q
In vitro cellular & developmental biology. Animal 2025 Mar;61(3):311-319
In vitro cellular & developmental biology. Animal 2025 Mar;61(3):311-319
Enhanced Vascular Smooth Muscle Cell and Extracellular Matrix Repair Using a Metal-Organic Framework-Based Co-Delivery System for Abdominal Aortic Aneurysm Therapy.
Lei J, Dong X, Huang Y, Wu Z, Peng Z, Li B, Wang R, Pan Y, Zheng X, Zhao Z, Lu X
Advanced healthcare materials 2025 Mar;14(6):e2402937
Advanced healthcare materials 2025 Mar;14(6):e2402937
Marrow adipogenic lineage precursors (MALPs) facilitate bone marrow recovery after chemotherapy.
Wang H, Yao L, Zhong L, Fang J, He Q, Busch TM, Cengel K, Qin L
Bone 2025 Jun;195:117446
Bone 2025 Jun;195:117446
The single-cell transcription reveals the aberrant differentiation trajectory of chondrocytes in the intervertebral disc for congenital scoliosis.
Wang J, Li H, Fu D, Zheng Y, Qian C, Li L, Qian M, Wang D
iScience 2025 Jun 20;28(6):112608
iScience 2025 Jun 20;28(6):112608
The upregulation of TNKS1 drives the phenotypic switching of vascular smooth muscle cells in aortic dissection through the activation of ferroptosis.
Xu X, Lin W, Liu T, Yuan C, Yan Y, Diao Y, Xiong J, Shao Y, Ni B
International immunopharmacology 2025 Jun 17;158:114722
International immunopharmacology 2025 Jun 17;158:114722
The Piezo1/Extracellular Signal-Regulated Kinase Signal Pathway Regulates Proliferation and Migration of Aortic Vascular Smooth Muscle Cells and Participates in Thoracic Aortic Aneurysm.
Nie W, Cao W, Zhuang Y, Yang S, Zhang H, Hu H, Shi C, Zhang H
Heart, lung & circulation 2025 Jul;34(7):704-718
Heart, lung & circulation 2025 Jul;34(7):704-718
Cytoplasmic and nuclear NFATc3 cooperatively contributes to vascular smooth muscle cell dysfunction and drives aortic aneurysm and dissection.
Liu X, Zhao L, Liu D, Zhao L, Tuo Y, Peng Q, Huang F, Song Z, Niu C, He X, Xu Y, Wan J, Zhu P, Jian Z, Guo J, Liu Y, Lu J, Liang S, Zheng S
Acta pharmaceutica Sinica. B 2025 Jul;15(7):3663-3684
Acta pharmaceutica Sinica. B 2025 Jul;15(7):3663-3684
Piezo1 promotes vibration-induced vascular smooth muscle injury by regulating the NF-κB/p65 axis.
Zeng Y, Wu Z, Xiong M, Liang Z, Chen Z, Huang H, Yang H, Chen Q
Communications biology 2025 Jan 21;8(1):96
Communications biology 2025 Jan 21;8(1):96
Uncovering endothelial to mesenchymal transition drivers in atherosclerosis via multi-omics analysis.
Huang Q, Gan Y, Zheng X, Yu Z, Huang Q, Huang M
BMC cardiovascular disorders 2025 Feb 17;25(1):104
BMC cardiovascular disorders 2025 Feb 17;25(1):104
High Shear Stress-Induced Endothelial Piezo1 Downregulation Promotes Intracranial Aneurysm Formation via the PDGF-BB/PDGFRβ Paracrine Signaling Pathway.
Lu Z, Li S, Xu F, Tang H, Zhu S, Wang C, Yang X, Huang Q
CNS neuroscience & therapeutics 2025 Dec;31(12):e70715
CNS neuroscience & therapeutics 2025 Dec;31(12):e70715
The Mechanism of Matrilin-2 Inhibiting the Progression of In-Stent Restenosis for Lower Extremity Arteriosclerosis Obliterans via TGF-β/Smad Signaling Pathway.
Li M, Ma C, Yin K, Lu F, Lu Z, Wang N, Zhang L, He Y, Dong J
Annals of vascular surgery 2025 Dec;121:65-72
Annals of vascular surgery 2025 Dec;121:65-72
TAGLN: a stiffness-driven prognostic biomarker for metastatic colorectal cancer.
Ye Y, Jia Y, Li W
Cancer cell international 2025 Dec 30;26(1):54
Cancer cell international 2025 Dec 30;26(1):54
Distinct populations of vascular smooth muscle and sinoatrial progenitors are localized adjacent to pro-epicardium.
Miao L, Nusrat A, Li J, Yin C, Lu Y, Kuang X, Sun D, Lo E, Song R, Huang W, Long X, McConnell BK, Singer HA, Schwartz RJ, Gunaratne P, Fan ZC, Kumar A, Zhou B, Munshi N, Evans SM, Wu M
Cell reports 2025 Dec 23;44(12):116580
Cell reports 2025 Dec 23;44(12):116580
Heterogeneity of common carotid artery and abdominal aorta: an angle of sphingolipid metabolism in vascular smooth muscle cells.
Li B, Zhou K, Chen K, Jiang S, Wang X, Gu Z, Gu C, Han Y, Liu Y, Chang Y, Bao J
Biomedical engineering online 2025 Dec 10;25(1):7
Biomedical engineering online 2025 Dec 10;25(1):7
Agathis dammara Extract and its Monomer Araucarone Attenuate Abdominal Aortic Aneurysm in Mice.
Zhang Q, Cai Z, Yu Z, Di C, Qiu Y, Qi R
Cardiovascular drugs and therapy 2025 Apr;39(2):239-257
Cardiovascular drugs and therapy 2025 Apr;39(2):239-257
Isovaleroylbinankadsurin A ameliorates atherosclerosis and restenosis by promoting LXRα signaling pathway and inhibiting TGF-β1 and FHL1 signaling pathways.
Shi Y, Liu L, Gong Y, Zhang C, Yang Y, Wang W, Qin L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156451
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156451
Analysis of the pathogenicity and pathological characteristics of NOTCH3 gene-sparing cysteine mutations in vitro and in vivo models.
Gong Z, Wang W, Zhao Y, Wang Y, Sun R, Zhang H, Wang F, Lu Y, Zhang J
Frontiers in molecular neuroscience 2024;17:1391040
Frontiers in molecular neuroscience 2024;17:1391040
Establishment and evaluation of a carotid artery dissection model in rats.
Zhang S, Han Z, Cao Y, Wu W, Liu Y, Yang S, Feng X, Yu C, Zhu Z, Dong Q, Han X
Frontiers in neurology 2024;15:1420278
Frontiers in neurology 2024;15:1420278
GSDMB involvement in the pathogenesis of abdominal aortic aneurysm through regulation of macrophage non-canonical pyroptosis.
Xie X, Shen X, Liu Y, Zuo Y, Wang S, Zhou Y, Li X, Wang K, Li B, Wang Z
Archives of biochemistry and biophysics 2024 Sep;759:110102
Archives of biochemistry and biophysics 2024 Sep;759:110102
STING1-accelerated vascular smooth muscle cell senescence-associated vascular calcification in diabetes is ameliorated by oleoylethanolamide via improved mitochondrial DNA oxidative damage.
Chen Z, Li X, Sun X, Xiao S, Chen T, Ren L, Liu N
Free radical biology & medicine 2024 Sep;222:437-455
Free radical biology & medicine 2024 Sep;222:437-455
Tudor-SN exacerbates pathological vascular remodeling by promoting the polyubiquitination of PTEN via NEDD4-1.
Wu Y, Chen Z, Zheng Z, Li X, Shu J, Mao R, An J, Fan S, Luo R, Guo Y, Xu W, Liang M, Huang K, Wang C
Journal of biomedical science 2024 Sep 5;31(1):88
Journal of biomedical science 2024 Sep 5;31(1):88
Insulin-transferrin-selenium promote formation of tissue-engineered vascular grafts in early stage of culture.
Sun X, Wang N, Jiang H, Liu Q, Xiao C, Xu J, Wu Y, Mei J, Wu S, Lin Z
Preparative biochemistry & biotechnology 2024 Oct;54(9):1186-1195
Preparative biochemistry & biotechnology 2024 Oct;54(9):1186-1195
The protective mechanism of sevoflurane in pulmonary arterial hypertension via downregulation of TRAF6.
Wang G, Wang C, Zhu P, Tian J, Yang H
Toxicology and applied pharmacology 2024 Oct;491:117065
Toxicology and applied pharmacology 2024 Oct;491:117065
Potential of dapagliflozin to prevent vascular remodeling in the rat carotid artery following balloon injury.
Matsushita K, Sato C, Bruckert C, Gong D, Amissi S, Hmadeh S, Fakih W, Remila L, Lessinger JM, Auger C, Jesel L, Ohlmann P, Kauffenstein G, Schini-Kerth VB, Morel O
Atherosclerosis 2024 Oct;397:117595
Atherosclerosis 2024 Oct;397:117595
CircLMBR1 inhibits phenotypic transformation of hypoxia-induced pulmonary artery smooth muscle via the splicing factor PUF60.
Wang H, Gao Y, Bai J, Liu H, Li Y, Zhang J, Ma C, Zhao X, Zhang L, Wan K, Zhu D
European journal of pharmacology 2024 Oct 5;980:176855
European journal of pharmacology 2024 Oct 5;980:176855
Construction of competitive endogenous RNA network and identification of potential regulatory axis in vascular calcification.
Xu T, Li Y, Cheng M, Jin J, Zhang S, Bai Y, Xu J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Oct 31;38(20):e70114
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Oct 31;38(20):e70114
Irisin suppresses PDGF-BB-induced proliferation of vascular smooth muscle cells in vitro by activating AMPK/mTOR-mediated autophagy.
Qi F, Deng Y, Huang W, Cai Y, Hong K, Xiang S
European journal of histochemistry : EJH 2024 Oct 15;68(4)
European journal of histochemistry : EJH 2024 Oct 15;68(4)
Nesfatin-1 enhances vascular smooth muscle calcification through facilitating BMP-2 osteogenic signaling.
Zhu XX, Meng XY, Chen G, Su JB, Fu X, Xu AJ, Liu Y, Hou XH, Qiu HB, Sun QY, Hu JY, Lv ZL, Sun HJ, Jiang HB, Han ZJ, Zhu J, Lu QB
Cell communication and signaling : CCS 2024 Oct 11;22(1):488
Cell communication and signaling : CCS 2024 Oct 11;22(1):488
Early growth response 1 exacerbates thoracic aortic aneurysm and dissection of mice by inducing the phenotypic switching of vascular smooth muscle cell through the activation of Krüppel-like factor 5.
Han X, Xu S, Hu K, Yu Y, Wang X, Qu C, Yang B, Liu X
Acta physiologica (Oxford, England) 2024 Nov;240(11):e14237
Acta physiologica (Oxford, England) 2024 Nov;240(11):e14237
Lutein protects senescent ciliary muscle against oxidative stress through the Keap1/Nrf2/ARE pathway.
Gao N, Gao X, Du M, Xiang Y, Zuo H, Huang R, Wan W, Hu K
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155982
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155982
High relative humidity environment alleviates hypoxia-induced pulmonary arterial hypertension in mice.
Song J, Cheng J, Ju W, Hu D, Zhuang D
Biochemical and biophysical research communications 2024 Nov 12;733:150681
Biochemical and biophysical research communications 2024 Nov 12;733:150681
TRIM65 promotes vascular smooth muscle cell phenotypic transformation by activating PI3K/Akt/mTOR signaling during atherogenesis.
Zhou ZX, Ma XF, Xiong WH, Ren Z, Jiang M, Deng NH, Zhou BB, Liu HT, Zhou K, Hu HJ, Tang HF, Zheng H, Jiang ZS
Atherosclerosis 2024 Mar;390:117430
Atherosclerosis 2024 Mar;390:117430
Knockdown of ARHGAP24 reduces intimal hyperplasia through inhibiting the proliferation and phenotypic switching of smooth muscle cells possibly by inactivating both AKT and ERK1/2 signaling pathways.
Liu W, Han J, Yang Q, Xia L, Chen C, Song J, Cai Y
Biochemistry and biophysics reports 2024 Mar;37:101591
Biochemistry and biophysics reports 2024 Mar;37:101591
Single-cell assessment of primary and stem cell-derived human trophoblast organoids as placenta-modeling platforms.
Shannon MJ, McNeill GL, Koksal B, Baltayeva J, Wächter J, Castellana B, Peñaherrera MS, Robinson WP, Leung PCK, Beristain AG
Developmental cell 2024 Mar 25;59(6):776-792.e11
Developmental cell 2024 Mar 25;59(6):776-792.e11
Fibulin 1, targeted by microRNA-24-3p, promotes cell proliferation and migration in vascular smooth muscle cells, contributing to the development of atherosclerosis in APOE(-/-) mice.
Ji T, Yan D, Huang Y, Luo M, Zhang Y, Xu T, Gao S, Zhang L, Ruan L, Zhang C
Gene 2024 Mar 10;898:148129
Gene 2024 Mar 10;898:148129
Targeting deubiquitinase OTUB1 protects vascular smooth muscle cells in atherosclerosis by modulating PDGFRβ.
Xu F, Chen H, Zhou C, Zang T, Wang R, Shen S, Li C, Yu Y, Pei Z, Shen L, Qian J, Ge J
Frontiers of medicine 2024 Jun;18(3):465-483
Frontiers of medicine 2024 Jun;18(3):465-483
High estrogen induces trans-differentiation of vascular smooth muscle cells to a macrophage-like phenotype resulting in aortic inflammation via inhibiting VHL/HIF1a/KLF4 axis.
Zhang R, Wang H, Cheng X, Fan K, Gao T, Qi X, Gao S, Zheng G, Dong H
Aging 2024 Jun 5;16(11):9876-9898
Aging 2024 Jun 5;16(11):9876-9898
Biphasic regulation of miR-17∼92 transcription during hypoxia: roles of HIF1 and p53 hyperphosphorylation at ser15.
Sun MR, Gonzalez S, Huang JB, Zhou Q, Cherukuri A, Adavadkar R, Yan HL, Sun SH, Zhou G, Raj JU, Chen T
American journal of physiology. Lung cellular and molecular physiology 2024 Jul 1;327(1):L102-L113
American journal of physiology. Lung cellular and molecular physiology 2024 Jul 1;327(1):L102-L113
68Ga-FAPI PET imaging monitors response to combined TGF-βR inhibition and immunotherapy in metastatic colorectal cancer.
Li K, Liu W, Yu H, Chen J, Tang W, Wang J, Qi M, Sun Y, Xu X, Zhang J, Li X, Guo W, Li X, Song S, Tang S
The Journal of clinical investigation 2024 Jan 4;134(4)
The Journal of clinical investigation 2024 Jan 4;134(4)
C1q/tumor necrosis factor-related protein-6 suppresses the angiotensin II-induced differentiation of cardiac fibroblasts to myofibroblasts via activation of the AMPK pathway.
Wu D, Li S, Chen M, Zhang S, Wang Q
Tissue & cell 2024 Dec;91:102627
Tissue & cell 2024 Dec;91:102627
Histone deacetylase 9 promotes osteogenic trans-differentiation of vascular smooth muscle cells via ferroptosis in chronic kidney disease vascular calcification.
Xiong L, Xiao Q, Chen R, Huang L, Gao J, Wang L, Li G, Li Y
Renal failure 2024 Dec;46(2):2422435
Renal failure 2024 Dec;46(2):2422435
Effects of soluble Klotho and Wnt/β-catenin signaling pathway in vascular calcification in chronic kidney disease model rats and the intervention of Shenyuan granules.
Zou X, Wang C, Wang L, Huang S, Deng D, Lin L, Wang X
Renal failure 2024 Dec;46(2):2394633
Renal failure 2024 Dec;46(2):2394633
Advanced glycosylation end products promote the progression of CKD-MBD in rats, and its natural inhibitor, quercetin, mitigates disease progression.
Wang Y, Hu C, Cao L, Liu Q, Li Y, Zhu T, Zhang D
Naunyn-Schmiedeberg's archives of pharmacology 2024 Dec;397(12):9675-9688
Naunyn-Schmiedeberg's archives of pharmacology 2024 Dec;397(12):9675-9688
Macropinocytosis controls metabolic stress-driven CAF subtype identity in pancreatic cancer.
Zhang Y, Ling L, Maganti S, Hope JL, Galapate CM, Carrette F, Duong-Polk K, Bagchi A, Scott DA, Lowy AM, Bradley LM, Commisso C
bioRxiv : the preprint server for biology 2024 Dec 5;
bioRxiv : the preprint server for biology 2024 Dec 5;
miR-200a-3p-enriched MSC-derived extracellular vesicles reverse erectile function in diabetic rats by targeting Keap1.
Zhang J, Zhao D, Zang Z, Ruan Z, Fu Q, Zhang K
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:116964
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:116964
M2 Macrophage-Derived Exosomes Inhibit Atherosclerosis Progression by Regulating the Proliferation, Migration, and Phenotypic Transformation of Smooth Muscle Cells.
Wang S, Wang X, Lv Y, Zhang Z, He T, Hao X, Wang S, Wang C, Meng J, Zhong K, Ye Z, Chen T, Cui Y
Frontiers in bioscience (Landmark edition) 2024 Aug 19;29(8):288
Frontiers in bioscience (Landmark edition) 2024 Aug 19;29(8):288
Single-cell RNA-Seq reveals the heterogeneity of fibroblasts within the tympanojugular paraganglioma microenvironment.
Wang S, Zhang B, Lou Z, Hu Y, Wang J, Wang J, Chen Z, Yin S
Heliyon 2024 Aug 15;10(15):e35478
Heliyon 2024 Aug 15;10(15):e35478
Quinic acid regulated TMA/TMAO-related lipid metabolism and vascular endothelial function through gut microbiota to inhibit atherosclerotic.
Jin Q, Zhang C, Chen R, Jiang L, Li H, Wu P, Li L
Journal of translational medicine 2024 Apr 15;22(1):352
Journal of translational medicine 2024 Apr 15;22(1):352
Trimethylamine N-oxide Promotes Atherosclerosis by Regulating Low-Density Lipoprotein-Induced Autophagy in Vascular Smooth Muscle Cells Through PI3K/AKT/mTOR Pathway.
Shi G, Zeng L, Shi J, Chen Y
International heart journal 2023;64(3):462-469
International heart journal 2023;64(3):462-469
miR-145 Alleviates Smooth Muscle Cell Phenotype Transition via ADAM17-Mediated ACE2 Shedding.
Wen J, Tang B, Guo L, Chen W, Tang X
International journal of hypertension 2023;2023:9497716
International journal of hypertension 2023;2023:9497716
DNMT1 mediates the disturbed flow-induced endothelial to mesenchymal transition through disrupting β-alanine and carnosine homeostasis.
Zhao J, Zhao C, Yang F, Jiang Z, Zhu J, Yao W, Pang W, Zhou J
Theranostics 2023;13(13):4392-4411
Theranostics 2023;13(13):4392-4411
S-propargyl-cysteine promotes the stability of atherosclerotic plaque via maintaining vascular muscle contractile phenotype.
Ping L, Zhi-Ming L, Bi-Shan Z, Lei Z, Bo Y, Yi-Chun Z, Ming-Jie W
Frontiers in cell and developmental biology 2023;11:1291170
Frontiers in cell and developmental biology 2023;11:1291170
MiR-21-3p in extracellular vesicles from vascular fibroblasts of spontaneously hypertensive rat promotes proliferation and migration of vascular smooth muscle cells.
Zheng F, Ye C, Ge R, Wang Y, Tian XL, Chen Q, Li YH, Zhu GQ, Zhou B
Life sciences 2023 Oct 1;330:122023
Life sciences 2023 Oct 1;330:122023
Clearance of Stress-Induced Premature Senescent Cells Alleviates the Formation of Abdominal Aortic Aneurysms.
Xie J, Tang Z, Chen Q, Jia X, Li C, Jin M, Wei G, Zheng H, Li X, Chen Y, Liao W, Liao Y, Bin J, Huang S
Aging and disease 2023 Oct 1;14(5):1778-1798
Aging and disease 2023 Oct 1;14(5):1778-1798
Asparagine endopeptidase protects podocytes in adriamycin-induced nephropathy by regulating actin dynamics through cleaving transgelin.
Qiu Y, Lei C, Zeng J, Xie Y, Cao Y, Yuan Q, Su H, Zhang Z, Zhang C
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Nov 1;31(11):3337-3354
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Nov 1;31(11):3337-3354
Interaction of TAGLN and USP1 promotes ZEB1 ubiquitination degradation in UV-induced skin photoaging.
Li Y, Huang X, Jin J, Zhang H, Yang K, Han J, Lv Y, Sun Y, Yao C, Lin T, Zhu C, Liu H
Cell & bioscience 2023 May 6;13(1):80
Cell & bioscience 2023 May 6;13(1):80
TGF-β-induced PI3K/AKT/mTOR pathway controls myofibroblast differentiation and secretory phenotype of valvular interstitial cells through the modulation of cellular senescence in a naturally occurring in vitro canine model of myxomatous mitral valve disease.
Tang Q, Markby GR, MacNair AJ, Tang K, Tkacz M, Parys M, Phadwal K, MacRae VE, Corcoran BM
Cell proliferation 2023 Jun;56(6):e13435
Cell proliferation 2023 Jun;56(6):e13435
Inflachromene inhibits intimal hyperplasia through the HMGB1/2- regulated TLR4-NF-κB pathway.
Teng S, Zhu Z, Wu C, He Y, Zhou S
International immunopharmacology 2023 Jun;119:110198
International immunopharmacology 2023 Jun;119:110198
Tumor-Associated Fibroblast-Derived Exosomal circDennd1b Promotes Pituitary Adenoma Progression by Modulating the miR-145-5p/ONECUT2 Axis and Activating the MAPK Pathway.
Jiang Q, Lei Z, Wang Z, Wang Q, Zhang Z, Liu X, Xing B, Li S, Guo X, Liu Y, Li X, Qi Y, Shu K, Zhang H, Huang Y, Lei T
Cancers 2023 Jun 27;15(13)
Cancers 2023 Jun 27;15(13)
A TEMPOL and rapamycin loaded nanofiber-covered stent favors endothelialization and mitigates neointimal hyperplasia and local inflammation.
Wang R, Lu J, Yin J, Chen H, Liu H, Xu F, Zang T, Xu R, Li C, Wu Y, Wu Q, Fei X, Zhu M, Shen L, Ge J
Bioactive materials 2023 Jan;19:666-677
Bioactive materials 2023 Jan;19:666-677
PKR deficiency delays vascular aging via inhibiting GSDMD-mediated endothelial cell hyperactivation.
Peng Z, Tan X, Xie L, Li Z, Zhou S, Li Y
iScience 2023 Jan 20;26(1):105909
iScience 2023 Jan 20;26(1):105909
Oleoylethanolamide alleviates hyperlipidaemia-mediated vascular calcification via attenuating mitochondrial DNA stress triggered autophagy-dependent ferroptosis by activating PPARα.
Chen Z, Sun X, Li X, Liu N
Biochemical pharmacology 2023 Feb;208:115379
Biochemical pharmacology 2023 Feb;208:115379
Overexpression of LOX-1 in hepatocytes protects vascular smooth muscle cells from phenotype transformation and wire injury induced carotid neoatherosclerosis through ALOX15.
Zhang Q, Du G, Tong L, Guo X, Wei Y
Biochimica et biophysica acta. Molecular basis of disease 2023 Dec;1869(8):166805
Biochimica et biophysica acta. Molecular basis of disease 2023 Dec;1869(8):166805
CDN1163 alleviates SERCA2 dysfunction-induced pulmonary vascular remodeling by inhibiting the phenotypic transition of pulmonary artery smooth muscle cells.
Yu W, Zhang Q, Qiu Y, Chen H, Huang X, Xiao L, Xu G, Li S, Hu P, Tong X
Clinical and experimental hypertension (New York, N.Y. : 1993) 2023 Dec 31;45(1):2272062
Clinical and experimental hypertension (New York, N.Y. : 1993) 2023 Dec 31;45(1):2272062
Axon guidance genes control hepatic artery development.
Gannoun L, De Schrevel C, Belle M, Dauguet N, Achouri Y, Loriot A, Vanderaa C, Cordi S, Dili A, Heremans Y, Rooman I, Leclercq IA, Jacquemin P, Gatto L, Lemaigre FP
Development (Cambridge, England) 2023 Aug 15;150(16)
Development (Cambridge, England) 2023 Aug 15;150(16)
miR-342-5p promotes vascular smooth muscle cell phenotypic transition through a negative-feedback regulation of Notch signaling via targeting FOXO3.
Wen T, Duan Y, Gao D, Zhang X, Zhang X, Liang L, Yang Z, Zhang P, Zhang J, Sun J, Feng Y, Zheng Q, Han H, Yan X
Life sciences 2023 Aug 1;326:121828
Life sciences 2023 Aug 1;326:121828
Exosomes Derived from Endothelial Cells Inhibit Neointimal Hyperplasia Induced by Carotid Artery Injury in Rats via ROS-NLRP3 Inflammasome Pathway.
Yang SY, Deng WW, Zhao RZ, Long XP, Wang DM, Guo HH, Jiang LX, Chen WM, Shi B
Bulletin of experimental biology and medicine 2023 Apr;174(6):762-767
Bulletin of experimental biology and medicine 2023 Apr;174(6):762-767
Fate mapping RNA-sequencing reveal Malat1 regulates Sca1(+) progenitor cells to vascular smooth muscle cells transition in vascular remodeling.
Lyu L, Li Z, Wen Z, He Y, Wang X, Jiang L, Zhou X, Huang C, Wu Y, Chen T, Guo X
Cellular and molecular life sciences : CMLS 2023 Apr 6;80(5):118
Cellular and molecular life sciences : CMLS 2023 Apr 6;80(5):118
BRG1 is involved in vascular calcification in chronic renal disease via autophagy of vascular smooth muscle cells.
Feng Y, Yu M, Wang C, Xia J, Huang L, Tang Y, Xiao Q, Pu L, Wang L, Li G, Li Y
iScience 2023 Apr 21;26(4):106485
iScience 2023 Apr 21;26(4):106485
Network pharmacology and experimental analysis to reveal the mechanism of Dan-Shen-Yin against endothelial to mesenchymal transition in atherosclerosis.
Hong M, Wu Y, Zhang H, Gu J, Chen J, Guan Y, Qin X, Li Y, Cao J
Frontiers in pharmacology 2022;13:946193
Frontiers in pharmacology 2022;13:946193
Theaflavin-3,3'-Digallate from Black Tea Inhibits Neointima Formation Through Suppression of the PDGFRβ Pathway in Vascular Smooth Muscle Cells.
Wu Y, Chen M, Chen Z, Shu J, Zhang L, Hu J, Yu H, Huang K, Liang M
Frontiers in pharmacology 2022;13:861319
Frontiers in pharmacology 2022;13:861319
Stromal Fibroblasts Counteract the Caveolin-1-Dependent Radiation Response of LNCaP Prostate Carcinoma Cells.
Wittka A, Ketteler J, Borgards L, Maier P, Herskind C, Jendrossek V, Klein D
Frontiers in oncology 2022;12:802482
Frontiers in oncology 2022;12:802482
Substitution of SERCA2 Cys(674) accelerates aortic aneurysm by inducing endoplasmic reticulum stress and promoting cell apoptosis.
Wang L, Yang Z, Wang S, Que Y, Shu X, Wu F, Liu G, Li S, Hu P, Chen H, Shi J, Tong X
British journal of pharmacology 2022 Sep;179(17):4423-4439
British journal of pharmacology 2022 Sep;179(17):4423-4439
Metabonomics profile analysis in inflammation-induced preterm birth and the potential role of metabolites in regulating premature cervical ripening.
Yan Y, Gu Z, Li B, Guo X, Zhang Z, Zhang R, Bian Z, Qiu J
Reproductive biology and endocrinology : RB&E 2022 Sep 6;20(1):135
Reproductive biology and endocrinology : RB&E 2022 Sep 6;20(1):135
Gut microbiome dysbiosis contributes to abdominal aortic aneurysm by promoting neutrophil extracellular trap formation.
Tian Z, Zhang Y, Zheng Z, Zhang M, Zhang T, Jin J, Zhang X, Yao G, Kong D, Zhang C, Wang Z, Zhang Q
Cell host & microbe 2022 Oct 12;30(10):1450-1463.e8
Cell host & microbe 2022 Oct 12;30(10):1450-1463.e8
Moxifloxacin induces aortic aneurysm and dissection by increasing osteopontin in mice.
Inada K, Koga M, Yamada A, Dohgu S, Yamauchi A
Biochemical and biophysical research communications 2022 Nov 12;629:1-5
Biochemical and biophysical research communications 2022 Nov 12;629:1-5
The substitution of SERCA2 redox cysteine 674 promotes pulmonary vascular remodeling by activating IRE1α/XBP1s pathway.
Yu W, Xu G, Chen H, Xiao L, Liu G, Hu P, Li S, Kasim V, Zeng C, Tong X
Acta pharmaceutica Sinica. B 2022 May;12(5):2315-2329
Acta pharmaceutica Sinica. B 2022 May;12(5):2315-2329
miR-335-5p regulates the proliferation, migration and phenotypic switching of vascular smooth muscle cells in aortic dissection by directly regulating SP1.
Ma R, Zhang D, Song Y, Kong J, Mu C, Shen P, Gui W
Acta biochimica et biophysica Sinica 2022 Jul 25;54(7):961-973
Acta biochimica et biophysica Sinica 2022 Jul 25;54(7):961-973
Kv7.4 channel is a key regulator of vascular inflammation and remodeling in neointimal hyperplasia and abdominal aortic aneurysms.
Fan XZ, Wang YY, Cui ZY, Cheng ZH, Zhang HL, Gamper N, Zhang F, Han M
Free radical biology & medicine 2022 Jan;178:111-124
Free radical biology & medicine 2022 Jan;178:111-124
SIRT6 protects vascular smooth muscle cells from osteogenic transdifferentiation via Runx2 in chronic kidney disease.
Li W, Feng W, Su X, Luo D, Li Z, Zhou Y, Zhu Y, Zhang M, Chen J, Liu B, Huang H
The Journal of clinical investigation 2022 Jan 4;132(1)
The Journal of clinical investigation 2022 Jan 4;132(1)
Ubiquitin-specific protease 47 is associated with vascular calcification in chronic kidney disease by regulating osteogenic transdifferentiation of vascular smooth muscle cells.
Xiao Q, Tang Y, Xia J, Luo H, Yu M, Chen S, Wang W, Pu L, Wang L, Li G, Li Y
Renal failure 2022 Dec;44(1):752-766
Renal failure 2022 Dec;44(1):752-766
Sclerostin is involved in osteogenic transdifferentiation of vascular smooth muscle cells in chronic kidney disease-associated vascular calcification with non-canonical Wnt signaling.
Xiao Q, Tang Y, Luo H, Chen S, Chen R, Yan Z, Pu L, Wang L, Li G, Li Y
Renal failure 2022 Dec;44(1):1426-1442
Renal failure 2022 Dec;44(1):1426-1442
Defective autophagy triggered by arterial cyclic stretch promotes neointimal hyperplasia in vein grafts via the p62/nrf2/slc7a11 signaling pathway.
Chen Y, Bao M, Liu JT, Bao H, Zhang SM, Lou Y, Qi YX
Journal of molecular and cellular cardiology 2022 Dec;173:101-114
Journal of molecular and cellular cardiology 2022 Dec;173:101-114
Bempedoic acid, an ATP citrate lyase inhibitor, reduces intimal hyperplasia via activation of AMPKα signaling pathway.
Liu W, Liu M, Xiong H, Xia L, Yang Q, Chen M, Cai Y, Li S
International immunopharmacology 2022 Dec;113(Pt A):109392
International immunopharmacology 2022 Dec;113(Pt A):109392
Human Placental Endothelial Cell and Trophoblast Heterogeneity and Differentiation Revealed by Single-Cell RNA Sequencing.
Li H, Peng H, Hong W, Wei Y, Tian H, Huang X, Jia L, Zheng J, Duan T, He Q, Wang K
Cells 2022 Dec 25;12(1)
Cells 2022 Dec 25;12(1)
Angiogenic factor AGGF1 blocks neointimal formation after vascular injury via interaction with integrin α7 on vascular smooth muscle cells.
Yu Y, Li Y, Peng H, Song Q, Da X, Li H, He Z, Ren X, Xu C, Yao Y, Wang QK
The Journal of biological chemistry 2022 Apr;298(4):101759
The Journal of biological chemistry 2022 Apr;298(4):101759
Transient expansion and myofibroblast conversion of adipogenic lineage precursors mediate bone marrow repair after radiation.
Zhong L, Yao L, Holdreith N, Yu W, Gui T, Miao Z, Elkaim Y, Li M, Gong Y, Pacifici M, Maity A, Busch TM, Joeng KS, Cengel K, Seale P, Tong W, Qin L
JCI insight 2022 Apr 8;7(7)
JCI insight 2022 Apr 8;7(7)
MED12 Regulates Smooth Muscle Cell Functions and Participates in the Development of Aortic Dissection.
Zhou Y, Zha L, Wu J, Wang M, Zhou M, Wu G, Cheng X, Huang Z, Xie Q, Tu X
Genes 2022 Apr 14;13(4)
Genes 2022 Apr 14;13(4)
PRDX2 Protects Against Atherosclerosis by Regulating the Phenotype and Function of the Vascular Smooth Muscle Cell.
Li J, Wang C, Wang W, Liu L, Zhang Q, Zhang J, Wang B, Wang S, Hou L, Gao C, Yu X, Sun L
Frontiers in cardiovascular medicine 2021;8:624796
Frontiers in cardiovascular medicine 2021;8:624796
MicroRNA‑199a‑5p regulates FOXC2 to control human vascular smooth muscle cell phenotypic switch.
Cao Y, Cao Z, Wang W, Jie X, Li L
Molecular medicine reports 2021 Sep;24(3)
Molecular medicine reports 2021 Sep;24(3)
Angiotensin II-Induced Long Non-Coding RNA Alivec Regulates Chondrogenesis in Vascular Smooth Muscle Cells.
Samara VA, Das S, Reddy MA, Tanwar VS, Stapleton K, Leung A, Abdollahi M, Ganguly R, Lanting L, Natarajan R
Cells 2021 Oct 9;10(10)
Cells 2021 Oct 9;10(10)
Targeting mitochondria-inflammation circle by renal denervation reduces atheroprone endothelial phenotypes and atherosclerosis.
Li Z, Li Q, Wang L, Li C, Xu M, Duan Y, Ma L, Li T, Chen Q, Wang Y, Wang Y, Feng J, Yin X, Wang X, Han J, Lu C
Redox biology 2021 Nov;47:102156
Redox biology 2021 Nov;47:102156
Metformin attenuates hyperlipidaemia-associated vascular calcification through anti-ferroptotic effects.
Ma WQ, Sun XJ, Zhu Y, Liu NF
Free radical biology & medicine 2021 Mar;165:229-242
Free radical biology & medicine 2021 Mar;165:229-242
TWIST1 induces phenotypic switching of vascular smooth muscle cells by downregulating p68 and microRNA-143/145.
Zhang J, Guo JR, Wu XL, Wang X, Zhu ZM, Wang Y, Gu X, Fan Y
FEBS open bio 2021 Mar;11(3):932-943
FEBS open bio 2021 Mar;11(3):932-943
Compound Danshen Dripping Pill inhibits doxorubicin or isoproterenol-induced cardiotoxicity.
Feng K, Liu Y, Sun J, Zhao C, Duan Y, Wang W, Yan K, Yan X, Sun H, Hu Y, Han J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111531
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111531
Intermittent short-duration reoxygenation protects against simulated high altitude-induced pulmonary hypertension in rats.
Lyu Q, Bai Y, Cheng J, Liu H, Li S, Yang J, Wang Z, Ma Y, Jiang M, Dong D, Yan Y, Shi Q, Ren X, Ma J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21212
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21212
Prostacyclin facilitates vascular smooth muscle cell phenotypic transformation via activating TP receptors when IP receptors are deficient.
Li Z, Luo W, Fang S, Chen X, Lin T, Zhou S, Zhang L, Yang W, Li Z, Ye J, Wang J, Liu P, Li Z
Acta physiologica (Oxford, England) 2021 Feb;231(2):e13555
Acta physiologica (Oxford, England) 2021 Feb;231(2):e13555
Kaposi's sarcoma-associated herpesvirus vFLIP promotes MEndT to generate hybrid M/E state for tumorigenesis.
Chen W, Ding Y, Liu D, Lu Z, Wang Y, Yuan Y
PLoS pathogens 2021 Dec;17(12):e1009600
PLoS pathogens 2021 Dec;17(12):e1009600
RETRACTED: The role of ATG-7 contributes to pulmonary hypertension by impacting vascular remodeling.
Yang X, Zhang L, Ye JQ, Wu XH, Zeng XX, Chen LW, Li YM
Journal of molecular and cellular cardiology 2021 Aug;157:1-13
Journal of molecular and cellular cardiology 2021 Aug;157:1-13
BGP-15 Inhibits Hyperglycemia-Aggravated VSMC Calcification Induced by High Phosphate.
Nagy A, Pethő D, Gesztelyi R, Juhász B, Balla G, Szilvássy Z, Balla J, Gáll T
International journal of molecular sciences 2021 Aug 26;22(17)
International journal of molecular sciences 2021 Aug 26;22(17)
The P2RY12 receptor promotes VSMC-derived foam cell formation by inhibiting autophagy in advanced atherosclerosis.
Pi S, Mao L, Chen J, Shi H, Liu Y, Guo X, Li Y, Zhou L, He H, Yu C, Liu J, Dang Y, Xia Y, He Q, Jin H, Li Y, Hu Y, Miao Y, Yue Z, Hu B
Autophagy 2021 Apr;17(4):980-1000
Autophagy 2021 Apr;17(4):980-1000
Hydrogen Sulfide Attenuates Aortic Remodeling in Aortic Dissection Associating with Moderated Inflammation and Oxidative Stress through a NO-Dependent Pathway.
Lu HY, Hsu HL, Li CH, Li SJ, Lin SJ, Shih CM, Shih CC
Antioxidants (Basel, Switzerland) 2021 Apr 27;10(5)
Antioxidants (Basel, Switzerland) 2021 Apr 27;10(5)
MicroRNA-143-5p modulates pulmonary artery smooth muscle cells functions in hypoxic pulmonary hypertension through targeting HIF-1α.
Tang BI, Tang MM, Xu QM, Guo JL, Xuan L, Zhou J, Wang XJ, Zhang H, Kang PF
Journal of biosciences 2020;45
Journal of biosciences 2020;45
Septin4 Prevents PDGF-BB-induced HAVSMC Phenotypic Transformation, Proliferation and Migration by Promoting SIRT1-STAT3 Deacetylation and Dephosphorylation.
Zhang N, Zhang Y, You S, Tian Y, Lu S, Cao L, Sun Y
International journal of biological sciences 2020;16(4):708-718
International journal of biological sciences 2020;16(4):708-718
Bioinformatics Analysis Reveals MicroRNA-193a-3p Regulates ACTG2 to Control Phenotype Switch in Human Vascular Smooth Muscle Cells.
Wang W, Wang Y, Piao H, Li B, Zhu Z, Li D, Wang T, Liu K
Frontiers in genetics 2020;11:572707
Frontiers in genetics 2020;11:572707
Salvia miltiorrhiza-derived miRNAs suppress vascular remodeling through regulating OTUD7B/KLF4/NMHC IIA axis.
Yang GS, Zheng B, Qin Y, Zhou J, Yang Z, Zhang XH, Zhao HY, Yang HJ, Wen JK
Theranostics 2020;10(17):7787-7811
Theranostics 2020;10(17):7787-7811
Paired box 9 regulates VSMC phenotypic transformation, proliferation, and migration via sonic hedgehog.
Xu J, Zhang Y, You S, Guo Y, Chen S, Chang Y, Zhang N, Sun Y
Life sciences 2020 Sep 15;257:118053
Life sciences 2020 Sep 15;257:118053
CTRP15 derived from cardiac myocytes attenuates TGFβ1-induced fibrotic response in cardiac fibroblasts.
Zhao Q, Zhang CL, Xiang RL, Wu LL, Li L
Cardiovascular drugs and therapy 2020 Oct;34(5):591-604
Cardiovascular drugs and therapy 2020 Oct;34(5):591-604
Inhibition of vascular calcification by microRNA-155-5p is accompanied by the inactivation of TGF-β1/Smad2/3 signaling pathway.
Zhao F, Wu Y, Yang W, Wu D, Wang C, Zhang F
Acta histochemica 2020 May;122(4):151551
Acta histochemica 2020 May;122(4):151551
miR-137 and its target T-type Ca(V) 3.1 channel modulate dedifferentiation and proliferation of cerebrovascular smooth muscle cells in simulated microgravity rats by regulating calcineurin/NFAT pathway.
Zhang B, Chen L, Bai YG, Song JB, Cheng JH, Ma HZ, Ma J, Xie MJ
Cell proliferation 2020 Mar;53(3):e12774
Cell proliferation 2020 Mar;53(3):e12774
T-cell death-associated gene 8 accelerates atherosclerosis by promoting vascular smooth muscle cell proliferation and migration.
Chen LD, Zhu WT, Cheng YY, Li ZH, Chen YQ, Yuan ZW, Lin CY, Jing DD, Liu ZQ, Yan PK
Atherosclerosis 2020 Mar;297:64-73
Atherosclerosis 2020 Mar;297:64-73
Characterization of Burn Eschar Pericytes.
Evdokiou A, Kanisicak O, Gierek S, Barry A, Ivey MJ, Zhang X, Bodnar RJ, Satish L
Journal of clinical medicine 2020 Feb 24;9(2)
Journal of clinical medicine 2020 Feb 24;9(2)
Mapping the Fine-Scale Organization and Plasticity of the Brain Vasculature.
Kirst C, Skriabine S, Vieites-Prado A, Topilko T, Bertin P, Gerschenfeld G, Verny F, Topilko P, Michalski N, Tessier-Lavigne M, Renier N
Cell 2020 Feb 20;180(4):780-795.e25
Cell 2020 Feb 20;180(4):780-795.e25
WWP2 regulates SIRT1-STAT3 acetylation and phosphorylation involved in hypertensive angiopathy.
Zhang Y, You S, Tian Y, Lu S, Cao L, Sun Y, Zhang N
Journal of cellular and molecular medicine 2020 Aug;24(16):9041-9054
Journal of cellular and molecular medicine 2020 Aug;24(16):9041-9054
Icotinib Attenuates Monocrotaline-Induced Pulmonary Hypertension by Preventing Pulmonary Arterial Smooth Muscle Cell Dysfunction.
Peng LY, Yu M, Yang MX, Liu P, Zhou H, Huang W, Kong H, Xie WP
American journal of hypertension 2020 Aug 4;33(8):775-783
American journal of hypertension 2020 Aug 4;33(8):775-783
2,3,7,8-Tetrachlorodibenzo-p-dioxin promotes injury-induced vascular neointima formation in mice.
Guo S, Zhang R, Liu Q, Wan Q, Wang Y, Yu Y, Liu G, Shen Y, Yu Y, Zhang J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10207-10217
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10207-10217
Reticulocalbin 2 enhances osteogenic differentiation of human vascular smooth muscle cells in diabetic conditions.
Chang Z, Yan G, Yan H, Zheng J, Liu Z
Life sciences 2019 Sep 15;233:116746
Life sciences 2019 Sep 15;233:116746
MicroRNA-122 promotes endothelial cell apoptosis by targeting XIAP: Therapeutic implication for atherosclerosis.
Li Y, Yang N, Dong B, Yang J, Kou L, Qin Q
Life sciences 2019 Sep 1;232:116590
Life sciences 2019 Sep 1;232:116590
SPARC induces phenotypic modulation of human brain vascular smooth muscle cells via AMPK/mTOR-mediated autophagy.
Li T, Tan X, Zhu S, Zhong W, Huang B, Sun J, Li F, Wang Y
Neuroscience letters 2019 Nov 1;712:134485
Neuroscience letters 2019 Nov 1;712:134485
Transactivation domain of Krüppel-like factor 15 negatively regulates angiotensin II-induced adventitial inflammation and fibrosis.
Lu YY, Li XD, Zhou HD, Shao S, He S, Hong MN, Liu JC, Xu YL, Wu YJ, Zhu DL, Wang JG, Gao PJ
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 May;33(5):6254-6268
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 May;33(5):6254-6268
Poly(ADP-ribose) polymerase 1 accelerates vascular calcification by upregulating Runx2.
Wang C, Xu W, An J, Liang M, Li Y, Zhang F, Tong Q, Huang K
Nature communications 2019 Mar 13;10(1):1203
Nature communications 2019 Mar 13;10(1):1203
Death-associated protein kinase 3 deficiency alleviates vascular calcification via AMPK-mediated inhibition of endoplasmic reticulum stress.
Li KX, Du Q, Wang HP, Sun HJ
European journal of pharmacology 2019 Jun 5;852:90-98
European journal of pharmacology 2019 Jun 5;852:90-98
Peroxisome Proliferator-Activated Receptor-γ Coactivator-1α Inhibits Vascular Calcification Through Sirtuin 3-Mediated Reduction of Mitochondrial Oxidative Stress.
Feng H, Wang JY, Yu B, Cong X, Zhang WG, Li L, Liu LM, Zhou Y, Zhang CL, Gu PL, Wu LL
Antioxidants & redox signaling 2019 Jul 1;31(1):75-91
Antioxidants & redox signaling 2019 Jul 1;31(1):75-91
Temporal and spatial changes of peroxiredoxin 2 levels in aortic media at very early stages of atherosclerotic lesion formation in apoE-knockout mice.
Kato R, Hayashi M, Aiuchi T, Sawada N, Obama T, Itabe H
Free radical biology & medicine 2019 Jan;130:348-360
Free radical biology & medicine 2019 Jan;130:348-360
Salusin-β Promotes Vascular Calcification via Nicotinamide Adenine Dinucleotide Phosphate/Reactive Oxygen Species-Mediated Klotho Downregulation.
Sun H, Zhang F, Xu Y, Sun S, Wang H, Du Q, Gu C, Black SM, Han Y, Tang H
Antioxidants & redox signaling 2019 Dec 20;31(18):1352-1370
Antioxidants & redox signaling 2019 Dec 20;31(18):1352-1370
CTRP13 attenuates vascular calcification by regulating Runx2.
Li Y, Wang W, Chao Y, Zhang F, Wang C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Aug;33(8):9627-9637
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Aug;33(8):9627-9637
Ultramorphological analysis of plaque advancement and cholesterol crystal formation in Ldlr knockout mouse atherosclerosis.
Baumer Y, McCurdy S, Jin X, Weatherby TM, Dey AK, Mehta NN, Yap JK, Kruth HS, Boisvert WA
Atherosclerosis 2019 Aug;287:100-111
Atherosclerosis 2019 Aug;287:100-111
Validation of Phosphodiesterase-10 as a Novel Target for Pulmonary Arterial Hypertension via Highly Selective and Subnanomolar Inhibitors.
Huang YY, Yu YF, Zhang C, Chen Y, Zhou Q, Li Z, Zhou S, Li Z, Guo L, Wu D, Wu Y, Luo HB
Journal of medicinal chemistry 2019 Apr 11;62(7):3707-3721
Journal of medicinal chemistry 2019 Apr 11;62(7):3707-3721
Glucagon-Like Peptide-1 Mediates the Protective Effect of the Dipeptidyl Peptidase IV Inhibitor on Renal Fibrosis via Reducing the Phenotypic Conversion of Renal Microvascular Cells in Monocrotaline-Treated Rats.
Xu J, Wang J, Cheng Y, Li X, He M, Zhu J, Han H, Wei G, Kong H, Xie W, Wang H, Zuo X
BioMed research international 2018;2018:1864107
BioMed research international 2018;2018:1864107
Teniposide regulates the phenotype switching of vascular smooth muscle cells in a miR-21-dependent manner.
Han H, Yang S, Liang Y, Zeng P, Liu L, Yang X, Duan Y, Han J, Chen Y
Biochemical and biophysical research communications 2018 Dec 2;506(4):1040-1046
Biochemical and biophysical research communications 2018 Dec 2;506(4):1040-1046
Chicoric acid prevents PDGF-BB-induced VSMC dedifferentiation, proliferation and migration by suppressing ROS/NFκB/mTOR/P70S6K signaling cascade.
Lu QB, Wan MY, Wang PY, Zhang CX, Xu DY, Liao X, Sun HJ
Redox biology 2018 Apr;14:656-668
Redox biology 2018 Apr;14:656-668
Hyperlipidemia-induced cholesterol crystal production by endothelial cells promotes atherogenesis.
Baumer Y, McCurdy S, Weatherby TM, Mehta NN, Halbherr S, Halbherr P, Yamazaki N, Boisvert WA
Nature communications 2017 Oct 24;8(1):1129
Nature communications 2017 Oct 24;8(1):1129
Targeting AGGF1 (angiogenic factor with G patch and FHA domains 1) for Blocking Neointimal Formation After Vascular Injury.
Yao Y, Hu Z, Ye J, Hu C, Song Q, Da X, Yu Y, Li H, Xu C, Chen Q, Wang QK
Journal of the American Heart Association 2017 Jun 25;6(6)
Journal of the American Heart Association 2017 Jun 25;6(6)
CD98 regulates vascular smooth muscle cell proliferation in atherosclerosis.
Baumer Y, McCurdy S, Alcala M, Mehta N, Lee BH, Ginsberg MH, Boisvert WA
Atherosclerosis 2017 Jan;256:105-114
Atherosclerosis 2017 Jan;256:105-114
Progression-related loss of stromal Caveolin 1 levels fosters the growth of human PC3 xenografts and mediates radiation resistance.
Panic A, Ketteler J, Reis H, Sak A, Herskind C, Maier P, Rübben H, Jendrossek V, Klein D
Scientific reports 2017 Jan 23;7:41138
Scientific reports 2017 Jan 23;7:41138
MicroRNA-99a inhibits insulin-induced proliferation, migration, dedifferentiation, and rapamycin resistance of vascular smooth muscle cells by inhibiting insulin-like growth factor-1 receptor and mammalian target of rapamycin.
Zhang ZW, Guo RW, Lv JL, Wang XM, Ye JS, Lu NH, Liang X, Yang LX
Biochemical and biophysical research communications 2017 Apr 29;486(2):414-422
Biochemical and biophysical research communications 2017 Apr 29;486(2):414-422
Vascular smooth muscle cell differentiation from human stem/progenitor cells.
Steinbach SK, Husain M
Methods (San Diego, Calif.) 2016 May 15;101:85-92
Methods (San Diego, Calif.) 2016 May 15;101:85-92
Protein profile screening: reduced expression of Sord in the mouse epididymis induced by nicotine inhibits tyrosine phosphorylation level in capacitated spermatozoa.
Dai J, Xu W, Zhao X, Zhang M, Zhang D, Nie D, Bao M, Wang Z, Wang L, Qiao Z
Reproduction (Cambridge, England) 2016 Mar;151(3):227-37
Reproduction (Cambridge, England) 2016 Mar;151(3):227-37
C1q/tumor necrosis factor-related protein-6 attenuates post-infarct cardiac fibrosis by targeting RhoA/MRTF-A pathway and inhibiting myofibroblast differentiation.
Lei H, Wu D, Wang JY, Li L, Zhang CL, Feng H, Fu FY, Wu LL
Basic research in cardiology 2015;110(4):35
Basic research in cardiology 2015;110(4):35
Expression and significance of NELIN and SM22α in varicose vein tissue.
Chen S, Qin S, Wang M, Zhang S
Experimental and therapeutic medicine 2015 Mar;9(3):845-849
Experimental and therapeutic medicine 2015 Mar;9(3):845-849
5-Aminolevulinic Acid-Mediated Sonodynamic Therapy Promotes Phenotypic Switching from Dedifferentiated to Differentiated Phenotype via Reactive Oxygen Species and p38 Mitogen-Activated Protein Kinase in Vascular Smooth Muscle Cells.
Dan J, Sun X, Li W, Zhang Y, Li X, Xu H, Li Z, Tian Z, Guo S, Yao J, Gao W, Tian Y
Ultrasound in medicine & biology 2015 Jun;41(6):1681-9
Ultrasound in medicine & biology 2015 Jun;41(6):1681-9
MicroRNA 302a is a novel modulator of cholesterol homeostasis and atherosclerosis.
Meiler S, Baumer Y, Toulmin E, Seng K, Boisvert WA
Arteriosclerosis, thrombosis, and vascular biology 2015 Feb;35(2):323-31
Arteriosclerosis, thrombosis, and vascular biology 2015 Feb;35(2):323-31
CTRP3 attenuates post-infarct cardiac fibrosis by targeting Smad3 activation and inhibiting myofibroblast differentiation.
Wu D, Lei H, Wang JY, Zhang CL, Feng H, Fu FY, Li L, Wu LL
Journal of molecular medicine (Berlin, Germany) 2015 Dec;93(12):1311-25
Journal of molecular medicine (Berlin, Germany) 2015 Dec;93(12):1311-25
Increased Expression of Tissue/Salivary Transgelin mRNA Predicts Poor Prognosis in Patients with Oral Squamous Cell Carcinoma (OSCC).
Bu J, Bu X, Liu B, Chen F, Chen P
Medical science monitor : international medical journal of experimental and clinical research 2015 Aug 5;21:2275-81
Medical science monitor : international medical journal of experimental and clinical research 2015 Aug 5;21:2275-81
Identification of colonic fibroblast secretomes reveals secretory factors regulating colon cancer cell proliferation.
Chen SX, Xu XE, Wang XQ, Cui SJ, Xu LL, Jiang YH, Zhang Y, Yan HB, Zhang Q, Qiao J, Yang PY, Liu F
Journal of proteomics 2014 Oct 14;110:155-71
Journal of proteomics 2014 Oct 14;110:155-71
Overexpression of c1q/tumor necrosis factor-related protein-3 promotes phosphate-induced vascular smooth muscle cell calcification both in vivo and in vitro.
Zhou Y, Wang JY, Feng H, Wang C, Li L, Wu D, Lei H, Li H, Wu LL
Arteriosclerosis, thrombosis, and vascular biology 2014 May;34(5):1002-10
Arteriosclerosis, thrombosis, and vascular biology 2014 May;34(5):1002-10
Transgelin as a therapeutic target to prevent hypoxic pulmonary hypertension.
Zhang R, Shi L, Zhou L, Zhang G, Wu X, Shao F, Ma G, Ying K
American journal of physiology. Lung cellular and molecular physiology 2014 Mar 15;306(6):L574-83
American journal of physiology. Lung cellular and molecular physiology 2014 Mar 15;306(6):L574-83
Transgelin overexpression in lung adenocarcinoma is associated with tumor progression.
Wu X, Dong L, Zhang R, Ying K, Shen H
International journal of molecular medicine 2014 Aug;34(2):585-91
International journal of molecular medicine 2014 Aug;34(2):585-91
Endothelial insulin-like growth factor-1 modulates proliferation and phenotype of smooth muscle cells induced by low shear stress.
Wang L, Han Y, Shen Y, Yan ZQ, Zhang P, Yao QP, Shen BR, Gao LZ, Qi YX, Jiang ZL
Annals of biomedical engineering 2014 Apr;42(4):776-86
Annals of biomedical engineering 2014 Apr;42(4):776-86
Selenoprotein K is required for palmitoylation of CD36 in macrophages: implications in foam cell formation and atherogenesis.
Meiler S, Baumer Y, Huang Z, Hoffmann FW, Fredericks GJ, Rose AH, Norton RL, Hoffmann PR, Boisvert WA
Journal of leukocyte biology 2013 May;93(5):771-80
Journal of leukocyte biology 2013 May;93(5):771-80
Adrenomedullin attenuates vascular calcification in fructose-induced insulin resistance rats.
Zhou YB, Gao Q, Li P, Han Y, Zhang F, Qi YF, Tang CS, Gao XY, Zhu GQ
Acta physiologica (Oxford, England) 2013 Mar;207(3):437-46
Acta physiologica (Oxford, England) 2013 Mar;207(3):437-46
Upregulation of transgelin is an independent factor predictive of poor prognosis in patients with advanced pancreatic cancer.
Zhou L, Zhang R, Zhang L, Sun Y, Yao W, Zhao A, Li J, Yuan Y
Cancer science 2013 Apr;104(4):423-30
Cancer science 2013 Apr;104(4):423-30
Serum-free differentiation of functional human coronary-like vascular smooth muscle cells from embryonic stem cells.
El-Mounayri O, Mihic A, Shikatani EA, Gagliardi M, Steinbach SK, Dubois N, Dacosta R, Li RK, Keller G, Husain M
Cardiovascular research 2013 Apr 1;98(1):125-35
Cardiovascular research 2013 Apr 1;98(1):125-35
ADAMTS-12 metalloprotease is necessary for normal inflammatory response.
Moncada-Pazos A, Obaya AJ, Llamazares M, Heljasvaara R, Suárez MF, Colado E, Noël A, Cal S, López-Otín C
The Journal of biological chemistry 2012 Nov 16;287(47):39554-63
The Journal of biological chemistry 2012 Nov 16;287(47):39554-63
Profiling of differentially expressed proteins in stage IV colorectal cancers with good and poor outcomes.
Kim HJ, Kang UB, Lee H, Jung JH, Lee ST, Yu MH, Kim H, Lee C
Journal of proteomics 2012 Jun 6;75(10):2983-97
Journal of proteomics 2012 Jun 6;75(10):2983-97
Directed differentiation of skin-derived precursors into functional vascular smooth muscle cells.
Steinbach SK, El-Mounayri O, DaCosta RS, Frontini MJ, Nong Z, Maeda A, Pickering JG, Miller FD, Husain M
Arteriosclerosis, thrombosis, and vascular biology 2011 Dec;31(12):2938-48
Arteriosclerosis, thrombosis, and vascular biology 2011 Dec;31(12):2938-48
Peptide-mediated disruption of calmodulin-cyclin E interactions inhibits proliferation of vascular smooth muscle cells and neointima formation.
Hui S, Choi J, Zaidi S, Momen A, Steinbach SK, Sadi AM, Ban K, Husain M
Circulation research 2011 Apr 29;108(9):1053-62
Circulation research 2011 Apr 29;108(9):1053-62
Up-regulation of two actin-associated proteins prompts pulmonary artery smooth muscle cell migration under hypoxia.
Zhang R, Zhou L, Li Q, Liu J, Yao W, Wan H
American journal of respiratory cell and molecular biology 2009 Oct;41(4):467-75
American journal of respiratory cell and molecular biology 2009 Oct;41(4):467-75
Dependence of proliferative vascular smooth muscle cells on CD98hc (4F2hc, SLC3A2).
Fogelstrand P, Féral CC, Zargham R, Ginsberg MH
The Journal of experimental medicine 2009 Oct 26;206(11):2397-406
The Journal of experimental medicine 2009 Oct 26;206(11):2397-406
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse colon tissue were subjected to SDS PAGE followed by western blot with 10493-1-AP( TAGLN Antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The transgelin/SM22 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human transgelin/SM22. This antibody recognizes human,mouse,rat antigen. The transgelin/SM22 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
