RA0471

antibody from Oursmab

Targeting: LY75 CD205, CLEC13B, DEC-205

Western blot (Supportive data in Antibodypedia)

ELISA (Supportive data in Antibodypedia)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0471

Provider

Oursmab

Product name

Oberotatug (Biosimilar Reference Antibody) (LY75)

Antibody type

Monoclonal

Description

Oberotatug is a humanized IgG1-kappa monoclonal antibody that specifically targets LY75, also known as CD205 or DEC-205, a type I transmembrane C-type lectin receptor. As an IgG1 isotype, it is designed to engage immune effector functions such as antibody-dependent cellular cytotoxicity (ADCC). DEC-205 is primarily expressed on dendritic cells (DCs) and some other antigen-presenting cells, where it plays a key role in antigen uptake and presentation. By binding to DEC-205, oberotatug may modulate dendritic cell function or serve as a vehicle to deliver antigens or therapeutic payloads specifically to these cells. It is being developed as a potential immunomodulatory agent for cancer immunotherapy or vaccine enhancement.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.

Western blot

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

Oberotatug (Biosimilar Reference Antibody) (LY75)-RA0471-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.

ELISA

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

ELISA plate pre-coated Antigen protein, can bind Oberotatug (Biosimilar Reference Antibody) (LY75)-RA0471 in a linear range of 3.91¨C31 ng/mL.