CABT-B130

antibody from Creative Diagnostics

Targeting: MYBPC3 CMH4, cMyBP-C, FHC

Western blot (Recommended by provider)

Antibody Data

Product number

CABT-B130

Provider

Creative Diagnostics

Product name

Anti-Myosin Binding Protein C monoclonal antibody, clone 09/0

Antibody type

Monoclonal

Description

MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Antibody clone number

09/0

Vial size

100_g

Storage

-20°C