Antibody data
- Antibody Data
- Antigen structure
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- Product number
- PABC-044 - Provider product page
- Provider
- Creative Biolabs
- Product name
- Human Anti-F9 Recombinant Antibody (clone 10C12)
- Antibody type
- Monoclonal
- Description
- Recombinant Human Antibody (10C12) is capable of binding to Factor IX, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-Factor IX mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-Factor IX mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. The 10C12 antibody binds tightly to full-length Factor IX or activated Factor IX with a Kd of 1. 6 nM and is specific for Factor IX but does not bind to the other vitamin K-dependent proteins despite the sequence similarity between the Gla domains of these proteins.
- Reactivity
- Human
- Host
- Human
- Antibody clone number
- 10C12
- Storage
- Centrifuge briefly prior to opening vial. Store at +4¡ãC short term (1-2 weeks). Aliquot and store at -20¡ãC long term. Avoid repeated freeze/thaw cycles.
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