Ab096310

antibody from Aladdin Scientific
Targeting: CHEK1 CHK1
Provider product page for Ab096310
Western blot
ELISA

Antibody data

Product number
Ab096310 - Provider product page
Provider
Aladdin Scientific
Product name
Chk1 Mouse mAb
Antibody type
Monoclonal
Description
Mouse Monoclonal (2G1D5) to CHK1, could be used for WB and ELISA.Application:WB: 1/500 - 1/2000 ELISA: 1/10000Protein Function:CHK1, also known as CHEK1, it is a kinase that phosphorylates cdc25, an important phosphatase in cell cycle control, particularly for entry into mitosis. Cdc25, when phosphorylated on serine 216 by chk1 becomes bound by an adaptor protein in the cytoplasm. Therefore it is inhibited from removing the inhibiting phosphate from MPF (mitotic/maturation promoting factor) added by Wee1. Consequently, a cell is prevented from entering mitosis. Chk1 can also phosphorylate p53 at Ser20 in vitro.
Reactivity
Human, Mouse
Host
Mouse
Conjugate
Unconjugated
Antigen sequence
AA 207-421
Isotype
IgG
Antibody clone number
2G1D5
Vial size
100_l,10_l,1ml,50_l
Concentration
1 mg/ml
Storage
Shipped at 4¡C. Store at +4¡C short term (1-2 weeks). Upon delivery aliquot. Store at -20¡C. Avoid freeze/thaw cycle.
CHEK1 protein structure - Ab096310 shown in red.