BS1625

antibody from Bioworld Technology, Inc

Targeting: CRYAB CRYA2, HSPB5

Immunohistochemistry

Antibody data

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Validation data

Product number: BS1625 - Provider product page
Provider: Bioworld Technology, Inc
Proper citation: Bioworld Technology Cat#BS1625, RRID:AB_1662711
Product name: Crystallin Ï«B (F15) polyclonal antibody
Antibody type: Polyclonal
Antigen: Synthetic peptide, corresponding to amino acids 1-50 of Human Crystallin-Ï«B.
Description: Ï«-crystallins consist of three gene products, Ï«A, Ï«B and Ï«C-crystallin, which are members of the small heat shock protein family (HSP 20). They are induced by heat shock, and act as molecular chaperones by holding denatured proteins in large soluble aggregates. However, unlike other molecular chaperones, Ï«-crystallins do not renature these proteins. Expression of Ï«A-crystallin is restricted to the lens. Defects in this gene cause autosomal dominant congenital cataracts (ADCC). The human Ï«B-crystallin gene product is expressed in many tissues, including lens, heart and skeletal muscle. Elevated expression of Ï«B-crystallin is associated with many neurological diseases, and a missense mutation in this gene has co-segregated in a family with a Desmin-related myopathy.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

CRYAB protein structure - BS1625 shown in red.