BS7135

antibody from Bioworld Technology, Inc
Targeting: HSPA8 HSC70, HSC71, HSP73, HSPA10
Provider product page for BS7135
Western blot
Immunohistochemistry

Antibody data

Product number
BS7135 - Provider product page
Provider
Bioworld Technology, Inc
Product name
HSC 70 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human HSC 70 .
Description
The HSP 70 family is composed of four highly conserved proteins: HSP 70, HSC 70, GRP 75 and GRP 78. These proteins serve a variety of roles: they act as molecular chaperones facilitating the assembly of multi-protein complexes, participate in the translocation of polypeptides across cell membranes and to the nucleus and aid in the proper folding of nascent polypeptide chains. All members of the family, except HSP 70, are constitutively expressed in primate cells. HSP 70 expression is strongly induced in response to heat stress. HSP 70 and HSC 70 (heat shock cognate protein 70) play key roles in the cytosolic endoplasmic reticulum and mitochondrial import machinery and are found in both the cytosol and nucleus of mammalian cells. Both HSP 70 and HSC 70 are involved in the chaperoning of nascent polypeptide chains and in protecting cells against the accumulation of improperly folded proteins.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
HSPA8 protein structure - BS7135 shown in red.