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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [14]
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- Product number
- ABIN361710 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN361710, RRID:AB_10773469
- Product name
- anti-Heat Shock 70kDa Protein 8 (HSPA8) antibody
- Antibody type
- Monoclonal
- Antigen
- Heat Shock 70kDa Protein 8 (HSPA8)
- Reactivity
- Human, Mouse, Rat, Bovine, Canine, Chicken/Avian, Hamster, Rabbit, Sheep, Xenopus, Yeast
- Host
- Mouse
- Antigen sequence
Chicken Hsp70/Hsp90 complex- Isotype
- IgG
- Vial size
- 200 ug
- Concentration
- 1 mg/mL
Submitted references Heat shock protein 70 inhibitors. 2. 2,5'-thiodipyrimidines, 5-(phenylthio)pyrimidines, 2-(pyridin-3-ylthio)pyrimidines, and 3-(phenylthio)pyridines as reversible binders to an allosteric site on heat shock protein 70.
Heat shock protein 70 inhibitors. 1. 2,5'-thiodipyrimidine and 5-(phenylthio)pyrimidine acrylamides as irreversible binders to an allosteric site on heat shock protein 70.
Affinity purification probes of potential use to investigate the endogenous Hsp70 interactome in cancer.
Identification of an allosteric pocket on human hsp70 reveals a mode of inhibition of this therapeutically important protein.
Identification of genes that modify ataxin-1-induced neurodegeneration.
Chaperone-mediated protein folding.
Chaperone-mediated protein folding.
Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1.
Mutational analysis of the hsp70-interacting protein Hip.
Molecular evolution of the HSP70 multigene family.
Identification of a 60-kilodalton stress-related protein, p60, which interacts with hsp90 and hsp70.
An ATPase domain common to prokaryotic cell cycle proteins, sugar kinases, actin, and hsp70 heat shock proteins.
Uncoating protein (hsc70) binds a conformationally labile domain of clathrin light chain LCa to stimulate ATP hydrolysis.
Polypeptide chain binding proteins: catalysts of protein folding and related processes in cells.
Taldone T, Kang Y, Patel HJ, Patel MR, Patel PD, Rodina A, Patel Y, Gozman A, Maharaj R, Clement CC, Lu A, Young JC, Chiosis G
Journal of medicinal chemistry 2014 Feb 27;57(4):1208-24
Journal of medicinal chemistry 2014 Feb 27;57(4):1208-24
Heat shock protein 70 inhibitors. 1. 2,5'-thiodipyrimidine and 5-(phenylthio)pyrimidine acrylamides as irreversible binders to an allosteric site on heat shock protein 70.
Kang Y, Taldone T, Patel HJ, Patel PD, Rodina A, Gozman A, Maharaj R, Clement CC, Patel MR, Brodsky JL, Young JC, Chiosis G
Journal of medicinal chemistry 2014 Feb 27;57(4):1188-207
Journal of medicinal chemistry 2014 Feb 27;57(4):1188-207
Affinity purification probes of potential use to investigate the endogenous Hsp70 interactome in cancer.
Rodina A, Taldone T, Kang Y, Patel PD, Koren J 3rd, Yan P, DaGama Gomes EM, Yang C, Patel MR, Shrestha L, Ochiana SO, Santarossa C, Maharaj R, Gozman A, Cox MB, Erdjument-Bromage H, Hendrickson RC, Cerchietti L, Melnick A, Guzman ML, Chiosis G
ACS chemical biology 2014 Aug 15;9(8):1698-705
ACS chemical biology 2014 Aug 15;9(8):1698-705
Identification of an allosteric pocket on human hsp70 reveals a mode of inhibition of this therapeutically important protein.
Rodina A, Patel PD, Kang Y, Patel Y, Baaklini I, Wong MJ, Taldone T, Yan P, Yang C, Maharaj R, Gozman A, Patel MR, Patel HJ, Chirico W, Erdjument-Bromage H, Talele TT, Young JC, Chiosis G
Chemistry & biology 2013 Dec 19;20(12):1469-80
Chemistry & biology 2013 Dec 19;20(12):1469-80
Identification of genes that modify ataxin-1-induced neurodegeneration.
Fernandez-Funez P, Nino-Rosales ML, de Gouyon B, She WC, Luchak JM, Martinez P, Turiegano E, Benito J, Capovilla M, Skinner PJ, McCall A, Canal I, Orr HT, Zoghbi HY, Botas J
Nature 2000 Nov 2;408(6808):101-6
Nature 2000 Nov 2;408(6808):101-6
Chaperone-mediated protein folding.
Fink AL
Physiological reviews 1999 Apr;79(2):425-49
Physiological reviews 1999 Apr;79(2):425-49
Chaperone-mediated protein folding.
Fink AL
Physiological reviews 1999 Apr;79(2):425-49
Physiological reviews 1999 Apr;79(2):425-49
Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1.
Zou J, Guo Y, Guettouche T, Smith DF, Voellmy R
Cell 1998 Aug 21;94(4):471-80
Cell 1998 Aug 21;94(4):471-80
Mutational analysis of the hsp70-interacting protein Hip.
Prapapanich V, Chen S, Toran EJ, Rimerman RA, Smith DF
Molecular and cellular biology 1996 Nov;16(11):6200-7
Molecular and cellular biology 1996 Nov;16(11):6200-7
Molecular evolution of the HSP70 multigene family.
Boorstein WR, Ziegelhoffer T, Craig EA
Journal of molecular evolution 1994 Jan;38(1):1-17
Journal of molecular evolution 1994 Jan;38(1):1-17
Identification of a 60-kilodalton stress-related protein, p60, which interacts with hsp90 and hsp70.
Smith DF, Sullivan WP, Marion TN, Zaitsu K, Madden B, McCormick DJ, Toft DO
Molecular and cellular biology 1993 Feb;13(2):869-76
Molecular and cellular biology 1993 Feb;13(2):869-76
An ATPase domain common to prokaryotic cell cycle proteins, sugar kinases, actin, and hsp70 heat shock proteins.
Bork P, Sander C, Valencia A
Proceedings of the National Academy of Sciences of the United States of America 1992 Aug 15;89(16):7290-4
Proceedings of the National Academy of Sciences of the United States of America 1992 Aug 15;89(16):7290-4
Uncoating protein (hsc70) binds a conformationally labile domain of clathrin light chain LCa to stimulate ATP hydrolysis.
DeLuca-Flaherty C, McKay DB, Parham P, Hill BL
Cell 1990 Sep 7;62(5):875-87
Cell 1990 Sep 7;62(5):875-87
Polypeptide chain binding proteins: catalysts of protein folding and related processes in cells.
Rothman JE
Cell 1989 Nov 17;59(4):591-601
Cell 1989 Nov 17;59(4):591-601
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