66394-1-Ig

antibody from Proteintech Group

Targeting: CALB1 CALB

Provider product page for 66394-1-Ig

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Immunocytochemistry

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [25]
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Product number: 66394-1-Ig - Provider product page
Provider: Proteintech Group
Product name: Calbindin-D28k antibody
Antibody type: Monoclonal
Description: Calbindin-D28k antibody (Cat. #66394-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat, pig and has been validated for the following applications: IF, IHC, WB, ELISA.
Reactivity: Human, Mouse, Rat, Porcine
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Antibody clone number: 1F8B9
Vial size: 20ul, 150ul

CALB1 protein structure - 66394-1-Ig shown in red.

Submitted references A decrease in Atp8a2 expression in Purkinje cells mediated acrylamide-induced cerebellar pathology in rats.

Yan K, Liu W, Xu S, Li L, Zhang J, Luo Z, Li G, Yang J
Toxicological research 2026 Mar;42(2):171-186

cGAS-STING signaling pathway promotes ischemic kidney injury by regulating HK3-mediated lipid accumulation.

Wang D, Zhou Z, Zhao Z, Liu M, Li Y, Mu L, Zhou H, Li X, Zhang F, Tian S, Zhou X, Shi Y
Free radical biology & medicine 2026 Jun;249:246-259

Integrative transcriptome-wide association analyses reveal PRKCG-linked GABAergic dysfunction in Fragile X-associated tremor/ataxia syndrome.

Jin Y, Cao Y, Ma W, Li R, Li Y, Kang Y, Huang J, Epstein MP, Guo X, Lim J, Rivera N, Zhou Y, Wen Z, Allen EG, Jin P
Nature communications 2026 Jan 8;17(1):1418

Cerebellar microglia-derived IL-17A mitigates autism-related behavioral and synaptic deficits.

Yin J, Li W, Shen LP, Zhang WL, Chen JY, Zhang BB, Chen YJ, Li T, Li HZ, Gao Z, Xie ST, Zhang QP, Zhang C, Zhang XY, Zhu JN
Molecular psychiatry 2026 Feb 9;

Ischaemic changes in cerebellar Purkinje cells suggest multiple causes of death in bath-related drowning.

Satoh F, Inoue H, Irie W, Sasaki C, Ochiai E, Kondo M, Nagata M, Kamogawa S
Journal of forensic and legal medicine 2026 Apr;119:103108

Characterizing molecular and behavioral changes arising from ROMK potassium channel deficiency in the cerebellum.

Agrimi J, Dunphy AJ, Zhong JC, Zhang W, Sbaiti N, Turner DR, Bernardele L, Foster DB, O'Rourke B, Paolocci N, Papanicolaou KN
Frontiers in behavioral neuroscience 2025;19:1681149

Estradiol Triggers Cerebellar MLI-PC LTP via ERβ/Protein Kinase C Signaling Cascades in Mice In Vivo.

Zhang ZY, Chen L, Sun MZ, Chen CY, Wang CY, Todo Y, Tang Z, Lv YC, Zou QY, Chu CP, Xu YH, Qiu DL
International journal of molecular sciences 2025 Oct 14;26(20)

Amyloid precursor protein modulates cerebellar Purkinje cell activity and motor function through regulation of Nav1.6 currents.

Ji MJ, Wu TX, Tian C, Cao X, Wei R, Yang YY, Meng X, Tang H, Cui T, Yang J, Tang X, Liu C
PLoS biology 2025 Nov;23(11):e3003513

Diagnostic value of TRIM22 in diabetic kidney disease and its mechanism.

Wang Q, Ge Q, Wang J, Wu Y, Qi X
Endocrine 2025 Mar;87(3):959-977

Activation of α2A-adrenergic Receptors Promotes Facial Sensory Stimulation-Evoked Cerebellar MLI-PC Long-Term Depression and Motor Learning in Vivo in Mice.

Weng WC, Zhang XD, Wang JY, Sun MZ, Chen CY, Jin XH, Qiu DL, Chu CP
Cerebellum (London, England) 2025 Jul 21;24(5):135

The endocytic adaptor AP-2 maintains Purkinje cell function by balancing cerebellar parallel and climbing fiber synapses.

Tolve M, Tutas J, Özer-Yildiz E, Klein I, Petzold A, Fritz VJ, Overhoff M, Silverman Q, Koletsou E, Liebsch F, Schwarz G, Korotkova T, Valtcheva S, Gatto G, Kononenko NL
Cell reports 2025 Feb 25;44(2):115256

Transcriptomics and Proteomics Identify Serotonin Transporter as a Promising Therapeutic Target for Essential Tremor.

Wang L, Zhou Z, Lin S, Li Y, Zhang S, Xu TL, Song XL, Wu Y
Molecular & cellular proteomics : MCP 2025 Dec;24(12):101442

Pathogenicity of Mediator Complex Subunit 27 (MED27) in a Neurodevelopmental Disorder with Cerebellar Atrophy.

Yiliyaer N, Li X, Guo T, Zhou H, Gong L, Yuan L, Fu Y, Qiao Y, Lui YL, Chen N, Lin P, Cheung HH, Ko H, Meng L, Chen X, Lei Y, Kwan KM, Wang H, Gu S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(48):e05535

NSD1-916aa encoded by CircNSD1 contributes to AKI-to-CKD transition through inducing ferroptosis in tubular epithelial cells.

Gao L, Zhang J, Chen C, Zhu S, Wei X, Tang G, Wang S, Wang Y, Liu X, Jiang L, Wu Y
JCI insight 2025 Aug 22;10(16)

PSTPIP2 ameliorates aristolochic acid nephropathy by suppressing interleukin-19-mediated neutrophil extracellular trap formation.

Du C, Xu C, Jia P, Cai N, Zhang Z, Meng W, Chen L, Zhou Z, Wang Q, Feng R, Li J, Meng X, Huang C, Ma T
eLife 2024 Feb 5;13

Clock knockout in inhibitory neurons reduces predisposition to epilepsy and influences anxiety-like behaviors in mice.

Deng L, Jiang H, Lin J, Xu D, Qi A, Guo Q, Li PP, Wang X, Liu JS, Fu X, Li P
Neurobiology of disease 2024 Apr;193:106457

Generation and characterization of an inducible renal proximal tubule-specific CreERT2 mouse.

Liang S, Wang Y, Kang M, Deng J, Chen L, Hong X, Hou FF, Zhang F
Frontiers in cell and developmental biology 2023;11:1171637

Integrative Single-Cell Transcriptomics and Epigenomics Mapping of the Fetal Retina Developmental Dynamics.

Li R, Liu J, Yi P, Yang X, Chen J, Zhao C, Liao X, Wang X, Xu Z, Lu H, Li H, Zhang Z, Liu X, Xiang J, Hu K, Qi H, Yu J, Yang P, Hou S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(16):e2206623

Clinical significance of Interleukin 17 receptor E in diabetic nephropathy.

Wang J, Wang X, Wang M, Wang J, Wu Y, Qi X
International immunopharmacology 2023 Jul;120:110324

Hippocampo-cortical circuits for selective memory encoding, routing, and replay.

Harvey RE, Robinson HL, Liu C, Oliva A, Fernandez-Ruiz A
Neuron 2023 Jul 5;111(13):2076-2090.e9

Retinoic acid supplementation ameliorates motor incoordination via RARα-CBLN2 in the cerebellum of a prenatal valproic acid-exposed rat autism model.

Yuan B, Luo L, Hu C, Lin F, Yang T, Chen J, Li T
Neuroscience letters 2023 Jul 13;809:137316

Mutational burden of XPNPEP3 leads to defects in mitochondrial complex I and cilia in NPHPL1.

Tong L, Rao J, Yang C, Xu J, Lu Y, Zhang Y, Cang X, Xie S, Mao J, Jiang P
iScience 2023 Aug 18;26(8):107446

Inflammasome Inhibition Prevents Motor Deficit and Cerebellar Degeneration Induced by Chronic Methamphetamine Administration.

Ding J, Shen L, Ye Y, Hu S, Ren Z, Liu T, Dai J, Li Z, Wang J, Luo Y, Zhang Q, Zhang X, Qi X, Huang J
Frontiers in molecular neuroscience 2022;15:861340

Rodent Area Prostriata Converges Multimodal Hierarchical Inputs and Projects to the Structures Important for Visuomotor Behaviors.

Chen CH, Hu JM, Zhang SY, Xiang XJ, Chen SQ, Ding SL
Frontiers in neuroscience 2021;15:772016

The long noncoding RNA Synage regulates synapse stability and neuronal function in the cerebellum.

Wang F, Wang Q, Liu B, Mei L, Ma S, Wang S, Wang R, Zhang Y, Niu C, Xiong Z, Zheng Y, Zhang Z, Shi J, Song X
Cell death and differentiation 2021 Sep;28(9):2634-2650

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