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- Antigen structure
- References [42]
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- Product number
- 20894-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20894-1-AP, RRID:AB_10755287
- Product name
- E-selectin /CD62E antibody
- Antibody type
- Polyclonal
- Description
- E-selectin /CD62E antibody (Cat. #20894-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references CD62E- and ROS-Responsive ETS Improves Cartilage Repair by Inhibiting Endothelial Cell Activation through OPA1-Mediated Mitochondrial Homeostasis.
Insulin Resistance Triggers Atherosclerosis: Caveolin 1 Cooperates with PKCzeta to Block Insulin Signaling in Vascular Endothelial Cells.
iNOS inhibitor S-methylisothiourea alleviates smoke inhalation-induced acute lung injury by suppressing inflammation and macrophage infiltration.
Astrocyte-Derived Extracellular Vesicular miR-143-3p Dampens Autophagic Degradation of Endothelial Adhesion Molecules and Promotes Neutrophil Transendothelial Migration after Acute Brain Injury.
Inflammation-Driven Nanohitchhiker Enhances Postoperative Immunotherapy by Alleviating Prostaglandin E2-Mediated Immunosuppression.
Ubiquitin ligase CHFR mediated degradation of VE-cadherin through ubiquitylation disrupts endothelial adherens junctions.
Novel Populations of Lung Capillary Endothelial Cells and Their Functional Significance.
Cardamonin targets KEAP1/NRF2 signaling for protection against atherosclerosis.
Aconitum carmichaelii Debx. Attenuates Heart Failure through Inhibiting Inflammation and Abnormal Vascular Remodeling.
ATP-citrate lyase controls endothelial gluco-lipogenic metabolism and vascular inflammation in sepsis-associated organ injury.
Disturbed Flow-Facilitated Margination and Targeting of Nanodisks Protect against Atherosclerosis.
Differentiation-inducing factor-1 reduces lipopolysaccharide-induced vascular cell adhesion molecule-1 by suppressing mTORC1-S6K signaling in vascular endothelial cells.
Inflammation Control and Tumor Growth Inhibition of Ovarian Cancer by Targeting Adhesion Molecules of E-Selectin.
3-(3-Hydroxyphenyl)propionic acid, a microbial metabolite of quercetin, inhibits monocyte binding to endothelial cells via modulating E-selectin expression.
Glycyrrhizic Acid Alleviates Lipopolysaccharide (LPS)-Induced Acute Lung Injury by Regulating Angiotensin-Converting Enzyme-2 (ACE2) and Caveolin-1 Signaling Pathway.
KLF2 alleviates endothelial cell injury and inhibits the formation of THP‑1 macrophage‑derived foam cells by activating Nrf2 and enhancing autophagy.
The mechanism underlying ICAM-1 and E-selectin-mediated hypertriglyceridemic pancreatitis-associated lung injury.
MAC mediates mammary duct epithelial cell injury in plasma cell mastitis and granulomatous mastitis.
Effects of 2,2',4'-trihydroxychalcone on the proliferation, metastasis and apoptosis of A549 human lung cancer cells.
Reducing Inflammation and Vascular Invasion in Intervertebral Disc Degeneration via Cystathionine-γ-Lyase Inhibitory Effect on E-Selectin.
Brain Microvascular Endothelial Cell-Derived HMGB1 Facilitates Monocyte Adhesion and Transmigration to Promote JEV Neuroinvasion.
Downregulation of CD151 restricts VCAM-1 mediated leukocyte infiltration to reduce neurobiological injuries after experimental stroke.
Identification of Overexpressed Genes in Malignant Pleural Mesothelioma.
MIN score predicts primary response to infliximab/adalimumab and vedolizumab therapy in patients with inflammatory bowel diseases.
VAMP3 and SNAP23 as Potential Targets for Preventing the Disturbed Flow-Accelerated Thrombus Formation.
Ketamine ameliorates hypoxia-induced endothelial injury in human umbilical vein endothelial cells.
The support of genetic evidence for cardiovascular risk induced by antineoplastic drugs.
Ketamine attenuates high-glucose-mediated endothelial inflammation in human umbilical vein endothelial cells.
Monocyte-derived extracellular vesicles upon treated by palmitate promote endothelial migration and monocytes attachment to endothelial cells.
DNA damage/cGAS-triggered up-regulation of MALAT1 promotes undesirable inflammatory responses in radiotherapy of cancer.
Propofol attenuates the adhesion of tumor and endothelial cells through inhibiting glycolysis in human umbilical vein endothelial cells.
Gender Difference in Damage-Mediated Signaling Contributes to Pulmonary Arterial Hypertension.
Chrysin Suppresses Vascular Endothelial Inflammation via Inhibiting the NF-κB Signaling Pathway.
MicroRNA-181a-5p and microRNA-181a-3p cooperatively restrict vascular inflammation and atherosclerosis.
Ticagrelor and clopidogrel suppress NF-κB signaling pathway to alleviate LPS-induced dysfunction in vein endothelial cells.
Toll-Like Receptor 3 Signaling Contributes to Regional Neutrophil Recruitment in Cultured Human Glomerular Endothelial Cells.
An E-selectin targeting and MMP-2-responsive dextran-curcumin polymeric prodrug for targeted therapy of acute kidney injury.
SET8 is involved in the regulation of hyperglycemic memory in human umbilical endothelial cells.
The BCR/ABL tyrosine kinase inhibitor, nilotinib, stimulates expression of IL-1β in vascular endothelium in association with downregulation of miR-3p.
A hot water extract of Curcuma longa inhibits adhesion molecule protein expression and monocyte adhesion to TNF-α-stimulated human endothelial cells.
CD40 ligand induces expression of vascular cell adhesion molecule 1 and E-selectin in orbital fibroblasts from patients with Graves' orbitopathy.
Dynamic shear stress regulation of inflammatory and thrombotic pathways in baboon endothelial outgrowth cells.
Tu P, Pan Y, Wang L, Li B, Sun X, Liang Z, Liu M, Zhao Z, Wu C, Wang J, Wang Z, Song Y, Zhang Y, Ma Y, Guo Y
Biomaterials research 2024;28:0006
Biomaterials research 2024;28:0006
Insulin Resistance Triggers Atherosclerosis: Caveolin 1 Cooperates with PKCzeta to Block Insulin Signaling in Vascular Endothelial Cells.
Tan J, Li X, Dou N
Cardiovascular drugs and therapy 2024 Oct;38(5):885-893
Cardiovascular drugs and therapy 2024 Oct;38(5):885-893
iNOS inhibitor S-methylisothiourea alleviates smoke inhalation-induced acute lung injury by suppressing inflammation and macrophage infiltration.
Shi Y, Cao Y, Han X, Xie L, Xiao K
International immunopharmacology 2024 Jan 5;126:111097
International immunopharmacology 2024 Jan 5;126:111097
Astrocyte-Derived Extracellular Vesicular miR-143-3p Dampens Autophagic Degradation of Endothelial Adhesion Molecules and Promotes Neutrophil Transendothelial Migration after Acute Brain Injury.
Wu X, Liu H, Hu Q, Wang J, Zhang S, Cui W, Shi Y, Bai H, Zhou J, Han L, Li L, Wu Y, Luo J, Wang T, Guo C, Wang Q, Ge S, Qu Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(5):e2305339
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(5):e2305339
Inflammation-Driven Nanohitchhiker Enhances Postoperative Immunotherapy by Alleviating Prostaglandin E2-Mediated Immunosuppression.
Liu Y, He J, Li M, Ren K, Zhao Z
ACS applied materials & interfaces 2024 Feb 14;16(6):6879-6893
ACS applied materials & interfaces 2024 Feb 14;16(6):6879-6893
Ubiquitin ligase CHFR mediated degradation of VE-cadherin through ubiquitylation disrupts endothelial adherens junctions.
Tiruppathi C, Wang DM, Ansari MO, Bano S, Tsukasaki Y, Mukhopadhyay A, Joshi JC, Loch C, Niessen HWM, Malik AB
Nature communications 2023 Oct 18;14(1):6582
Nature communications 2023 Oct 18;14(1):6582
Novel Populations of Lung Capillary Endothelial Cells and Their Functional Significance.
James J, Dekan A, Niihori M, McClain N, Varghese M, Bharti D, Lawal OS, Padilla-Rodrigez M, Yi D, Dai Z, Gusev O, Rafikova O, Rafikov R
Research square 2023 May 3;
Research square 2023 May 3;
Cardamonin targets KEAP1/NRF2 signaling for protection against atherosclerosis.
Fan P, Meng H, Hao W, Zheng Y, Li H, Zhang Z, Du L, Guo X, Wang D, Wang Y, Wu H
Food & function 2023 May 22;14(10):4905-4920
Food & function 2023 May 22;14(10):4905-4920
Aconitum carmichaelii Debx. Attenuates Heart Failure through Inhibiting Inflammation and Abnormal Vascular Remodeling.
Xing Z, Chen J, Yu T, Li X, Dong W, Peng C, Li D
International journal of molecular sciences 2023 Mar 19;24(6)
International journal of molecular sciences 2023 Mar 19;24(6)
ATP-citrate lyase controls endothelial gluco-lipogenic metabolism and vascular inflammation in sepsis-associated organ injury.
Li R, Meng M, Chen Y, Pan T, Li Y, Deng Y, Zhang R, Tian R, Xu W, Zheng X, Gong F, Liu J, Tang H, Ding X, Tang Y, Annane D, Chen E, Qu H, Li L
Cell death & disease 2023 Jul 6;14(7):401
Cell death & disease 2023 Jul 6;14(7):401
Disturbed Flow-Facilitated Margination and Targeting of Nanodisks Protect against Atherosclerosis.
Zhao CR, Li J, Jiang ZT, Zhu JJ, Zhao JN, Yang QR, Yao W, Pang W, Li N, Yu M, Gan Y, Zhou J
Small (Weinheim an der Bergstrasse, Germany) 2023 Jan;19(2):e2204694
Small (Weinheim an der Bergstrasse, Germany) 2023 Jan;19(2):e2204694
Differentiation-inducing factor-1 reduces lipopolysaccharide-induced vascular cell adhesion molecule-1 by suppressing mTORC1-S6K signaling in vascular endothelial cells.
Arioka M, Seto-Tetsuo F, Inoue T, Miura K, Ishikane S, Igawa K, Tomooka K, Takahashi-Yanaga F, Sasaguri T
Life sciences 2023 Dec 15;335:122278
Life sciences 2023 Dec 15;335:122278
Inflammation Control and Tumor Growth Inhibition of Ovarian Cancer by Targeting Adhesion Molecules of E-Selectin.
Yang B, Yin S, Zhou Z, Huang L, Xi M
Cancers 2023 Apr 4;15(7)
Cancers 2023 Apr 4;15(7)
3-(3-Hydroxyphenyl)propionic acid, a microbial metabolite of quercetin, inhibits monocyte binding to endothelial cells via modulating E-selectin expression.
Feng J, Ge C, Li W, Li R
Fitoterapia 2022 Jan;156:105071
Fitoterapia 2022 Jan;156:105071
Glycyrrhizic Acid Alleviates Lipopolysaccharide (LPS)-Induced Acute Lung Injury by Regulating Angiotensin-Converting Enzyme-2 (ACE2) and Caveolin-1 Signaling Pathway.
Chen Y, Qu L, Li Y, Chen C, He W, Shen L, Zhang R
Inflammation 2022 Feb;45(1):253-266
Inflammation 2022 Feb;45(1):253-266
KLF2 alleviates endothelial cell injury and inhibits the formation of THP‑1 macrophage‑derived foam cells by activating Nrf2 and enhancing autophagy.
Tan Z, Ren H, Liu Y, Yang H, Luo Q, Deng X
Experimental and therapeutic medicine 2022 Dec;24(6):737
Experimental and therapeutic medicine 2022 Dec;24(6):737
The mechanism underlying ICAM-1 and E-selectin-mediated hypertriglyceridemic pancreatitis-associated lung injury.
Yu R, Hou C, Peng Y, Zhu X, Shi C, Huang D, Miao Y, Li Q
Molecular immunology 2022 Dec;152:55-66
Molecular immunology 2022 Dec;152:55-66
MAC mediates mammary duct epithelial cell injury in plasma cell mastitis and granulomatous mastitis.
Zhang HJ, Ding PP, Zhang XS, Wang XC, Sun DW, Bu QA, Li XQ
International immunopharmacology 2022 Dec;113(Pt A):109303
International immunopharmacology 2022 Dec;113(Pt A):109303
Effects of 2,2',4'-trihydroxychalcone on the proliferation, metastasis and apoptosis of A549 human lung cancer cells.
Sun JL, Cao ZQ, Sun SW, Sun ZH, Sun SH, Ye JF, Leng P
Oncology letters 2022 Apr;23(4):116
Oncology letters 2022 Apr;23(4):116
Reducing Inflammation and Vascular Invasion in Intervertebral Disc Degeneration via Cystathionine-γ-Lyase Inhibitory Effect on E-Selectin.
Xu H, Wei K, Tu J, Chen Y, He Y, Ding Y, Xu H, Bao X, Xie H, Fang H, Wang H
Frontiers in cell and developmental biology 2021;9:741046
Frontiers in cell and developmental biology 2021;9:741046
Brain Microvascular Endothelial Cell-Derived HMGB1 Facilitates Monocyte Adhesion and Transmigration to Promote JEV Neuroinvasion.
Zou SS, Zou QC, Xiong WJ, Cui NY, Wang K, Liu HX, Lou WJ, Higazy D, Zhang YG, Cui M
Frontiers in cellular and infection microbiology 2021;11:701820
Frontiers in cellular and infection microbiology 2021;11:701820
Downregulation of CD151 restricts VCAM-1 mediated leukocyte infiltration to reduce neurobiological injuries after experimental stroke.
Gao C, Jia W, Xu W, Wu Q, Wu J
Journal of neuroinflammation 2021 May 22;18(1):118
Journal of neuroinflammation 2021 May 22;18(1):118
Identification of Overexpressed Genes in Malignant Pleural Mesothelioma.
Morani F, Bisceglia L, Rosini G, Mutti L, Melaiu O, Landi S, Gemignani F
International journal of molecular sciences 2021 Mar 8;22(5)
International journal of molecular sciences 2021 Mar 8;22(5)
MIN score predicts primary response to infliximab/adalimumab and vedolizumab therapy in patients with inflammatory bowel diseases.
Shi Y, He W, Zhong M, Yu M
Genomics 2021 Jul;113(4):1988-1998
Genomics 2021 Jul;113(4):1988-1998
VAMP3 and SNAP23 as Potential Targets for Preventing the Disturbed Flow-Accelerated Thrombus Formation.
Zhu JJ, Jiang ZT, Liu C, Xi YF, Wang J, Yang FF, Yao WJ, Pang W, Han LL, Zhang YH, Sun AQ, Zhou J
Frontiers in cell and developmental biology 2020;8:576826
Frontiers in cell and developmental biology 2020;8:576826
Ketamine ameliorates hypoxia-induced endothelial injury in human umbilical vein endothelial cells.
Zhou X, Liu J, Yang S, Su Y, Meng Z, Hu Y
Clinics (Sao Paulo, Brazil) 2020;75:e1865
Clinics (Sao Paulo, Brazil) 2020;75:e1865
The support of genetic evidence for cardiovascular risk induced by antineoplastic drugs.
Cui H, Zuo S, Liu Z, Liu H, Wang J, You T, Zheng Z, Zhou Y, Qian X, Yao H, Xie L, Liu T, Sham PC, Yu Y, Li MJ
Science advances 2020 Oct;6(42)
Science advances 2020 Oct;6(42)
Ketamine attenuates high-glucose-mediated endothelial inflammation in human umbilical vein endothelial cells.
Wang T, Zhu H, Hou Y, Duan W, Meng F, Liu Y
Canadian journal of physiology and pharmacology 2020 Mar;98(3):156-161
Canadian journal of physiology and pharmacology 2020 Mar;98(3):156-161
Monocyte-derived extracellular vesicles upon treated by palmitate promote endothelial migration and monocytes attachment to endothelial cells.
Gao W, Guo X, Wang Y, Jian D, Li M
Biochemical and biophysical research communications 2020 Mar 12;523(3):685-691
Biochemical and biophysical research communications 2020 Mar 12;523(3):685-691
DNA damage/cGAS-triggered up-regulation of MALAT1 promotes undesirable inflammatory responses in radiotherapy of cancer.
Yuan C, Wang D, Zhang N, Wang Z, Yang F, He J, Sun R, Yang X, Hu J, Wu M
Biochemical and biophysical research communications 2020 Aug 6;528(4):746-752
Biochemical and biophysical research communications 2020 Aug 6;528(4):746-752
Propofol attenuates the adhesion of tumor and endothelial cells through inhibiting glycolysis in human umbilical vein endothelial cells.
Qi J, Wu Q, Zhu X, Zhang S, Chen X, Chen W, Sun Z, Zhu M, Miao C
Acta biochimica et biophysica Sinica 2019 Nov 18;51(11):1114-1122
Acta biochimica et biophysica Sinica 2019 Nov 18;51(11):1114-1122
Gender Difference in Damage-Mediated Signaling Contributes to Pulmonary Arterial Hypertension.
Rafikov R, Nair V, Sinari S, Babu H, Sullivan JC, Yuan JX, Desai AA, Rafikova O
Antioxidants & redox signaling 2019 Nov 1;31(13):917-932
Antioxidants & redox signaling 2019 Nov 1;31(13):917-932
Chrysin Suppresses Vascular Endothelial Inflammation via Inhibiting the NF-κB Signaling Pathway.
Zhao S, Liang M, Wang Y, Hu J, Zhong Y, Li J, Huang K, Li Y
Journal of cardiovascular pharmacology and therapeutics 2019 May;24(3):278-287
Journal of cardiovascular pharmacology and therapeutics 2019 May;24(3):278-287
MicroRNA-181a-5p and microRNA-181a-3p cooperatively restrict vascular inflammation and atherosclerosis.
Su Y, Yuan J, Zhang F, Lei Q, Zhang T, Li K, Guo J, Hong Y, Bu G, Lv X, Liang S, Ou J, Zhou J, Luo B, Shang J
Cell death & disease 2019 May 7;10(5):365
Cell death & disease 2019 May 7;10(5):365
Ticagrelor and clopidogrel suppress NF-κB signaling pathway to alleviate LPS-induced dysfunction in vein endothelial cells.
Jia Z, Huang Y, Ji X, Sun J, Fu G
BMC cardiovascular disorders 2019 Dec 30;19(1):318
BMC cardiovascular disorders 2019 Dec 30;19(1):318
Toll-Like Receptor 3 Signaling Contributes to Regional Neutrophil Recruitment in Cultured Human Glomerular Endothelial Cells.
Liu Q, Imaizumi T, Kawaguchi S, Aizawa T, Matsumiya T, Watanabe S, Tsugawa K, Yoshida H, Tsuruga K, Joh K, Kijima H, Tanaka H
Nephron 2018;139(4):349-358
Nephron 2018;139(4):349-358
An E-selectin targeting and MMP-2-responsive dextran-curcumin polymeric prodrug for targeted therapy of acute kidney injury.
Hu JB, Liu D, Qi J, Lu KJ, Jin FY, Ying XY, You J, Du YZ
Biomaterials science 2018 Nov 20;6(12):3397-3409
Biomaterials science 2018 Nov 20;6(12):3397-3409
SET8 is involved in the regulation of hyperglycemic memory in human umbilical endothelial cells.
Chen X, Wu Q, Jiang H, Wang J, Zhao Y, Xu Y, Zhu M
Acta biochimica et biophysica Sinica 2018 Jul 1;50(7):635-642
Acta biochimica et biophysica Sinica 2018 Jul 1;50(7):635-642
The BCR/ABL tyrosine kinase inhibitor, nilotinib, stimulates expression of IL-1β in vascular endothelium in association with downregulation of miR-3p.
Sukegawa M, Wang X, Nishioka C, Pan B, Xu K, Ohkawara H, Hamasaki Y, Mita M, Nakamura K, Okamoto M, Shimura H, Ohta M, Ikezoe T
Leukemia research 2017 Jul;58:83-90
Leukemia research 2017 Jul;58:83-90
A hot water extract of Curcuma longa inhibits adhesion molecule protein expression and monocyte adhesion to TNF-α-stimulated human endothelial cells.
Kawasaki K, Muroyama K, Yamamoto N, Murosaki S
Bioscience, biotechnology, and biochemistry 2015;79(10):1654-9
Bioscience, biotechnology, and biochemistry 2015;79(10):1654-9
CD40 ligand induces expression of vascular cell adhesion molecule 1 and E-selectin in orbital fibroblasts from patients with Graves' orbitopathy.
Wang H, Zhu LS, Cheng JW, Cai JP, Li Y, Ma XY, Wei RL
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2015 Apr;253(4):573-82
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2015 Apr;253(4):573-82
Dynamic shear stress regulation of inflammatory and thrombotic pathways in baboon endothelial outgrowth cells.
Ankeny RF, Hinds MT, Nerem RM
Tissue engineering. Part A 2013 Jul;19(13-14):1573-82
Tissue engineering. Part A 2013 Jul;19(13-14):1573-82
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The E-selectin /CD62E antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human E-selectin /CD62E. This antibody recognizes human,mouse,rat antigen. The E-selectin /CD62E antibody has been validated for the following applications: ELISA, WB analysis.
