Antibody data
- Antibody Data
- Antigen structure
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- Product number
- TAB-014-F(E) - Provider product page
- Provider
- Creative Biolabs
- Product name
- Anti-Human CEA Recombinant Antibody Fab Fragment (Arcitumomab)
- Antibody type
- Monoclonal
- Description
- Recombinant monoclonal antibody Fragment Fab to Human CEA. Technetium (99mTc) arcitumomab is a drug used for the diagnostic imaging of colorectal cancers. It consists of the Fab' fragment of a monoclonal antibody (arcitumomab, trade name CEA-Scan) and a radionuclide, technetium-99m. Technetium (99mTc) arcitumomab is an immunoconjugate. Arcitumomab is a Fab' fragment of IMMU-4, a murine IgG1 monoclonal antibody extracted from the ascites of mice. The enzyme pepsin cleaves the F(ab')2 fragment off the antibody. From this, the Fab' fragment is prepared by mild reduction. Before application, arcitumomab is reconstituted with a solution of the radioactive agent sodium pertechnetate (99mTc) from a technetium generator.
- Reactivity
- Human
- Host
- Mouse
- Storage
- Store at -20¡ãC. Avoid multiple freeze/thaw cycles.
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