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- Antibody Data
- Antigen structure
- References [14]
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- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
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- Product number
- 16848-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16848-1-AP, RRID:AB_2134417
- Product name
- Cytokeratin 1-specific antibody
- Antibody type
- Polyclonal
- Description
- Cytokeratin 1-specific antibody (Cat. #16848-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Denticleless E3 ubiquitin protein ligase (DTL) maintains the proliferation and differentiation of epidermis and hair follicles during skin development.
Nuclear IL-33 Plays an Important Role in EGFR-Mediated Keratinocyte Migration by Regulating the Activation of Signal Transducer and Activator of Transcription 3 and NF-κB.
Macrophage lineage cells-derived migrasomes activate complement-dependent blood-brain barrier damage in cerebral amyloid angiopathy mouse model.
Histone deacetylase 6-mediated downregulation of TMEM100 expedites the development and progression of non-small cell lung cancer.
IL-22 Downregulates Peptidylarginine Deiminase-1 in Human Keratinocytes: Adding Another Piece to the IL-22 Puzzle in Epidermal Barrier Formation.
c-Myc Upregulated by High Glucose Inhibits HaCaT Differentiation by S100A6 Transcriptional Activation.
Nuclear IL-33 Plays an Important Role in the Suppression of FLG, LOR, Keratin 1, and Keratin 10 by IL-4 and IL-13 in Human Keratinocytes.
Cabs1 Maintains Structural Integrity of Mouse Sperm Flagella during Epididymal Transit of Sperm.
PDGF-BB/SA/Dex injectable hydrogels accelerate BMSC-mediated functional full thickness skin wound repair by promoting angiogenesis.
The potential of Diosgenin in treating psoriasis: Studies from HaCaT keratinocytes and imiquimod-induced murine model.
Cultivation of Hair Matrix Cells from Cashmere Goat Skins and Exemplified Applications.
Effects of mevalonate kinase interference on cell differentiation, apoptosis, prenylation and geranylgeranylation of human keratinocytes are attenuated by farnesyl pyrophosphate or geranylgeranyl pyrophosphate.
Inactivation of mitogen-activated protein kinase signaling pathway reduces caspase-14 expression in impaired keratinocytes.
Loss-of-function Mutation in PMVK Causes Autosomal Dominant Disseminated Superficial Porokeratosis.
Lin Y, Tang W, Huang P, Wang Z, Duan L, Jia C, Sun R, Liu L, Shen J
Developmental dynamics : an official publication of the American Association of Anatomists 2024 Jul;253(7):635-647
Developmental dynamics : an official publication of the American Association of Anatomists 2024 Jul;253(7):635-647
Nuclear IL-33 Plays an Important Role in EGFR-Mediated Keratinocyte Migration by Regulating the Activation of Signal Transducer and Activator of Transcription 3 and NF-κB.
Dai X, Shiraishi K, Muto J, Mori H, Murakami M, Sayama K
JID innovations : skin science from molecules to population health 2023 Jul;3(4):100205
JID innovations : skin science from molecules to population health 2023 Jul;3(4):100205
Macrophage lineage cells-derived migrasomes activate complement-dependent blood-brain barrier damage in cerebral amyloid angiopathy mouse model.
Hu M, Li T, Ma X, Liu S, Li C, Huang Z, Lin Y, Wu R, Wang S, Lu D, Lu T, Men X, Shen S, Huang H, Liu Y, Song K, Jian B, Jiang Y, Qiu W, Liu Q, Lu Z, Cai W
Nature communications 2023 Jul 4;14(1):3945
Nature communications 2023 Jul 4;14(1):3945
Histone deacetylase 6-mediated downregulation of TMEM100 expedites the development and progression of non-small cell lung cancer.
Wang Y, Ha M, Li M, Zhang L, Chen Y
Human cell 2022 Jan;35(1):271-285
Human cell 2022 Jan;35(1):271-285
IL-22 Downregulates Peptidylarginine Deiminase-1 in Human Keratinocytes: Adding Another Piece to the IL-22 Puzzle in Epidermal Barrier Formation.
Padhi A, Srivastava A, Ramesh A, Ehrström M, Simon M, Sonkoly E, Eidsmo L, Bergman P, Lysell J
The Journal of investigative dermatology 2022 Feb;142(2):333-342.e6
The Journal of investigative dermatology 2022 Feb;142(2):333-342.e6
c-Myc Upregulated by High Glucose Inhibits HaCaT Differentiation by S100A6 Transcriptional Activation.
Zhang J, Yang P, Liu D, Gao M, Wang J, Wang X, Liu Y, Zhang X
Frontiers in endocrinology 2021;12:676403
Frontiers in endocrinology 2021;12:676403
Nuclear IL-33 Plays an Important Role in the Suppression of FLG, LOR, Keratin 1, and Keratin 10 by IL-4 and IL-13 in Human Keratinocytes.
Dai X, Utsunomiya R, Shiraishi K, Mori H, Muto J, Murakami M, Sayama K
The Journal of investigative dermatology 2021 Nov;141(11):2646-2655.e6
The Journal of investigative dermatology 2021 Nov;141(11):2646-2655.e6
Cabs1 Maintains Structural Integrity of Mouse Sperm Flagella during Epididymal Transit of Sperm.
Zhang X, Zhou W, Zhang P, Gao F, Zhao X, Shum WW, Zeng X
International journal of molecular sciences 2021 Jan 11;22(2)
International journal of molecular sciences 2021 Jan 11;22(2)
PDGF-BB/SA/Dex injectable hydrogels accelerate BMSC-mediated functional full thickness skin wound repair by promoting angiogenesis.
Zhang Z, Li Z, Wang Y, Wang Q, Yao M, Zhao L, Shi J, Guan F, Ma S
Journal of materials chemistry. B 2021 Aug 21;9(31):6176-6189
Journal of materials chemistry. B 2021 Aug 21;9(31):6176-6189
The potential of Diosgenin in treating psoriasis: Studies from HaCaT keratinocytes and imiquimod-induced murine model.
Wu S, Zhao M, Sun Y, Xie M, Le K, Xu M, Huang C
Life sciences 2020 Jan 15;241:117115
Life sciences 2020 Jan 15;241:117115
Cultivation of Hair Matrix Cells from Cashmere Goat Skins and Exemplified Applications.
Ma S, Wang L, Zong B, Wang Y, Wang X, Shi Y, Yang Y, Chen Y
Animals : an open access journal from MDPI 2020 Aug 12;10(8)
Animals : an open access journal from MDPI 2020 Aug 12;10(8)
Effects of mevalonate kinase interference on cell differentiation, apoptosis, prenylation and geranylgeranylation of human keratinocytes are attenuated by farnesyl pyrophosphate or geranylgeranyl pyrophosphate.
Li M, Min W, Wang J, Wang L, Li Y, Zhou N, Yang Z, Qian Q
Experimental and therapeutic medicine 2020 Apr;19(4):2861-2870
Experimental and therapeutic medicine 2020 Apr;19(4):2861-2870
Inactivation of mitogen-activated protein kinase signaling pathway reduces caspase-14 expression in impaired keratinocytes.
Dang N, Pang S, Song H, An L, Ma X
Iranian journal of basic medical sciences 2016 Jan;19(1):28-33
Iranian journal of basic medical sciences 2016 Jan;19(1):28-33
Loss-of-function Mutation in PMVK Causes Autosomal Dominant Disseminated Superficial Porokeratosis.
Wang J, Liu Y, Liu F, Huang C, Han S, Lv Y, Liu CJ, Zhang S, Qin Y, Ling L, Gao M, Yu S, Li C, Huang M, Liao S, Hu X, Lu Z, Liu X, Jiang T, Tang Z, Zhang H, Guo AY, Liu M
Scientific reports 2016 Apr 7;6:24226
Scientific reports 2016 Apr 7;6:24226
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A375 cells were subjected to SDS PAGE followed by western blot with 16848-1-AP(KRT1-specific antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-KRT1-specific (IP:16848-1-AP, 3ug; Detection:16848-1-AP 1:500) with A431 cells lysate 3500ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human skin using 16848-1-AP(KRT1-specific antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Cytokeratin 1-specific antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human Cytokeratin 1-specific. This antibody recognizes human antigen. The Cytokeratin 1-specific antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
