Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 16848-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16848-1-AP, RRID:AB_2134417
- Product name
- Cytokeratin 1-specific antibody
- Antibody type
- Polyclonal
- Description
- Cytokeratin 1-specific antibody (Cat. #16848-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Histone deacetylase 6-mediated downregulation of TMEM100 expedites the development and progression of non-small cell lung cancer.
c-Myc Upregulated by High Glucose Inhibits HaCaT Differentiation by S100A6 Transcriptional Activation.
Nuclear IL-33 Plays an Important Role in the Suppression of FLG, LOR, Keratin 1, and Keratin 10 by IL-4 and IL-13 in Human Keratinocytes.
Cabs1 Maintains Structural Integrity of Mouse Sperm Flagella during Epididymal Transit of Sperm.
IL-22 Downregulates Peptidylarginine Deiminase-1 in Human Keratinocytes: Adding Another Piece to the IL-22 Puzzle in Epidermal Barrier Formation.
The potential of Diosgenin in treating psoriasis: Studies from HaCaT keratinocytes and imiquimod-induced murine model.
Cultivation of Hair Matrix Cells from Cashmere Goat Skins and Exemplified Applications.
Effects of mevalonate kinase interference on cell differentiation, apoptosis, prenylation and geranylgeranylation of human keratinocytes are attenuated by farnesyl pyrophosphate or geranylgeranyl pyrophosphate.
Loss-of-function Mutation in PMVK Causes Autosomal Dominant Disseminated Superficial Porokeratosis.
Wang Y, Ha M, Li M, Zhang L, Chen Y
Human cell 2022 Jan;35(1):271-285
Human cell 2022 Jan;35(1):271-285
c-Myc Upregulated by High Glucose Inhibits HaCaT Differentiation by S100A6 Transcriptional Activation.
Zhang J, Yang P, Liu D, Gao M, Wang J, Wang X, Liu Y, Zhang X
Frontiers in endocrinology 2021;12:676403
Frontiers in endocrinology 2021;12:676403
Nuclear IL-33 Plays an Important Role in the Suppression of FLG, LOR, Keratin 1, and Keratin 10 by IL-4 and IL-13 in Human Keratinocytes.
Dai X, Utsunomiya R, Shiraishi K, Mori H, Muto J, Murakami M, Sayama K
The Journal of investigative dermatology 2021 Nov;141(11):2646-2655.e6
The Journal of investigative dermatology 2021 Nov;141(11):2646-2655.e6
Cabs1 Maintains Structural Integrity of Mouse Sperm Flagella during Epididymal Transit of Sperm.
Zhang X, Zhou W, Zhang P, Gao F, Zhao X, Shum WW, Zeng X
International journal of molecular sciences 2021 Jan 11;22(2)
International journal of molecular sciences 2021 Jan 11;22(2)
IL-22 Downregulates Peptidylarginine Deiminase-1 in Human Keratinocytes: Adding Another Piece to the IL-22 Puzzle in Epidermal Barrier Formation.
Padhi A, Srivastava A, Ramesh A, Ehrström M, Simon M, Sonkoly E, Eidsmo L, Bergman P, Lysell J
The Journal of investigative dermatology 2021 Aug 2;
The Journal of investigative dermatology 2021 Aug 2;
The potential of Diosgenin in treating psoriasis: Studies from HaCaT keratinocytes and imiquimod-induced murine model.
Wu S, Zhao M, Sun Y, Xie M, Le K, Xu M, Huang C
Life sciences 2020 Jan 15;241:117115
Life sciences 2020 Jan 15;241:117115
Cultivation of Hair Matrix Cells from Cashmere Goat Skins and Exemplified Applications.
Ma S, Wang L, Zong B, Wang Y, Wang X, Shi Y, Yang Y, Chen Y
Animals : an open access journal from MDPI 2020 Aug 12;10(8)
Animals : an open access journal from MDPI 2020 Aug 12;10(8)
Effects of mevalonate kinase interference on cell differentiation, apoptosis, prenylation and geranylgeranylation of human keratinocytes are attenuated by farnesyl pyrophosphate or geranylgeranyl pyrophosphate.
Li M, Min W, Wang J, Wang L, Li Y, Zhou N, Yang Z, Qian Q
Experimental and therapeutic medicine 2020 Apr;19(4):2861-2870
Experimental and therapeutic medicine 2020 Apr;19(4):2861-2870
Loss-of-function Mutation in PMVK Causes Autosomal Dominant Disseminated Superficial Porokeratosis.
Wang J, Liu Y, Liu F, Huang C, Han S, Lv Y, Liu CJ, Zhang S, Qin Y, Ling L, Gao M, Yu S, Li C, Huang M, Liao S, Hu X, Lu Z, Liu X, Jiang T, Tang Z, Zhang H, Guo AY, Liu M
Scientific reports 2016 Apr 7;6:24226
Scientific reports 2016 Apr 7;6:24226
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A375 cells were subjected to SDS PAGE followed by western blot with 16848-1-AP(KRT1-specific antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-KRT1-specific (IP:16848-1-AP, 3ug; Detection:16848-1-AP 1:500) with A431 cells lysate 3500ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human skin using 16848-1-AP(KRT1-specific antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Cytokeratin 1-specific antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human Cytokeratin 1-specific. This antibody recognizes human antigen. The Cytokeratin 1-specific antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.