GTX23137

antibody from GeneTex

Targeting: FLG

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

GTX23137

Provider

GeneTex

Proper citation

GeneTex Cat#GTX23137, RRID:AB_384952

Product name

Filaggrin antibody [FLG01]

Antibody type

Monoclonal

Reactivity

Human

Host

Mouse

References

Submitted references

Eczema in Psoriatico: An Important Differential Diagnosis Between Chronic Allergic Contact Dermatitis and Psoriasis in Palmoplantar Localization.

Kolesnik M, Franke I, Lux A, Quist SR, Gollnick HP
Acta dermato-venereologica 2018 Jan 12;98(1):50-58

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Orchestrated control of filaggrin-actin scaffolds underpins cornification.

Gutowska-Owsiak D, de La Serna JB, Fritzsche M, Naeem A, Podobas EI, Leeming M, Colin-York H, O'Shaughnessy R, Eggeling C, Ogg GS
Cell death & disease 2018 Apr 1;9(4):412

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A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic dermatitis.

Naeem AS, Tommasi C, Cole C, Brown SJ, Zhu Y, Way B, Willis Owen SA, Moffatt M, Cookson WO, Harper JI, Di WL, Brown SJ, Reinheckel T, O'Shaughnessy RF
The Journal of allergy and clinical immunology 2017 Apr;139(4):1228-1241

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Human eccrine sweat gland cells can reconstitute a stratified epidermis.

Biedermann T, Pontiggia L, Böttcher-Haberzeth S, Tharakan S, Braziulis E, Schiestl C, Meuli M, Reichmann E
The Journal of investigative dermatology 2010 Aug;130(8):1996-2009