Antibody data
- Antibody Data
- Antigen structure
- References [283]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 22952-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#22952-1-AP, RRID:AB_2783651
- Product name
- Osteopontin antibody
- Antibody type
- Polyclonal
- Description
- Osteopontin antibody (Cat. #22952-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat, mouse and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Metabolic Control During Macrophage Polarization by a Citrate-Functionalized Scaffold for Maintaining Bone Homeostasis.
Bioactive peptide relieves glucocorticoid-induced osteoporosis by giant macrocyclic encapsulation.
Urchin-like multiscale structured fluorinated hydroxyapatite as versatile filler for caries restoration dental resin composites.
CNPY2 governs PDGF‑BB‑treated vascular smooth muscle cell proliferation, migration and phenotypic transformation via the Akt/mTOR/GSK‑3β signaling pathway.
Asprosin aggravates atherosclerosis via regulating the phenotype transformation of vascular smooth muscle cells.
Multifunctional tannic acid-based nanocomposite methacrylated silk fibroin hydrogel with the ability to scavenge reactive oxygen species and reduce inflammation for bone regeneration.
Injectable, anti-collapse, adhesive, plastic and bioactive bone graft substitute promotes bone regeneration by moderating oxidative stress in osteoporotic bone defect.
An integrated multi-omics analysis reveals osteokines involved in global regulation.
Fibrous periosteum repairs bone fracture and maintains the healed bone throughout mouse adulthood.
Activation of CaMKII/HDAC4 by SDF1 contributes to pulmonary arterial hypertension via stabilization Runx2.
Carbonylation of Runx2 at K176 by 4-Hydroxynonenal Accelerates Vascular Calcification.
Targeting osteopontin alleviates endometriosis and inflammation by inhibiting the RhoA/ROS axis and achieves non-invasive in vitro detection via menstrual blood.
Murine double minute 2-mediated estrogen receptor 1 degradation activates macrophage migration inhibitory factor to promote vascular smooth muscle cell dedifferentiation and oxidative stress during thoracic aortic aneurysm progression.
Identification of SLC2A1 as a predictive biomarker for survival and response to immunotherapy in lung squamous cell carcinoma.
Hypermethylation of Bmp2 and Fgfr2 Promoter Regions in Bone Marrow Mesenchymal Stem Cells Leads to Bone Loss in Prematurely Aged Mice.
Mechanism of Porphyra Yezoensis Polysaccharides in Inhibiting Hyperoxalate-Induced Renal Injury and Crystal Deposition.
Single-cell RNA sequencing reveals epithelial cells driving brain metastasis in lung adenocarcinoma.
Resolvin D1 attenuates Ang II-induced hypertension in mice by inhibiting the proliferation, migration and phenotypic transformation of vascular smooth muscle cells by blocking the RhoA/mitogen-activated protein kinase pathway.
HOXB9 promotes osteosarcoma cell survival and malignancy under glucose starvation via upregulating SPP1 expression.
Integrated bioinformatics analysis identified leucine rich repeat containing 15 and secreted phosphoprotein 1 as hub genes for calcific aortic valve disease and osteoarthritis.
SPP1 could be an immunological and prognostic biomarker: From pan-cancer comprehensive analysis to osteosarcoma validation.
Single-Cell RNA Transcriptome of the Human Endometrium Reveals Epithelial Characterizations Associated with Recurrent Implantation Failure.
KLF2/PPARγ axis contributes to trauma-induced heterotopic ossification by regulating mitochondrial dysfunction.
Myeloid-derived growth factor suppresses VSMC dedifferentiation and attenuates postinjury neointimal formation in rats by activating S1PR2 and its downstream signaling.
Isoliquiritin treatment of osteoporosis by promoting osteogenic differentiation and autophagy of bone marrow mesenchymal stem cells.
3D-printed tri-element-doped hydroxyapatite/ polycaprolactone composite scaffolds with antibacterial potential for osteosarcoma therapy and bone regeneration.
Carp scales derived double cross-linking hydrogels achieve collagen peptides sustained-released for bone regeneration.
A novel lncRNA GM15416 regulates osteoblast apoptosis and differentiation through the c-Fos/Fas axis and mitigates osteoporosis.
S-adenosylmethionine attenuates angiotensin II-induced aortic dissection formation by inhibiting vascular smooth muscle cell phenotypic switch and autophagy.
Regulation of the immune microenvironment by pioglitazone-loaded polylactic glycolic acid nanosphere composite scaffolds to promote vascularization and bone regeneration.
Nanoscaled Titanium Oxide Layer Provokes Quick Osseointegration on 3D-Printed Dental Implants: A Domino Effect Induced by Hydrophilic Surface.
Single-cell profiling of the microenvironment in human bone metastatic renal cell carcinoma.
PRMT3 methylates HIF-1α to enhance the vascular calcification induced by chronic kidney disease.
Alamandine attenuates ovariectomy-induced osteoporosis by promoting osteogenic differentiation via AMPK/eNOS axis.
Nerve growth factor promote osteogenic differentiation of dental pulp stem cells through MEK/ERK signalling pathways.
Biomimetic cryogel promotes the repair of osteoporotic bone defects through altering the ROS niche via down-regulating the ROMO1.
A multifunctional quercetin/polycaprolactone electrospun fibrous membrane for periodontal bone regeneration.
Coenzyme Q10 Protects Against Hyperlipidemia-Induced Osteoporosis by Improving Mitochondrial Function via Modulating miR-130b-3p/PGC-1α Pathway.
Three Birds, One Stone: An Osteo-Microenvironment Stage-Regulative Scaffold for Bone Defect Repair through Modulating Early Osteo-Immunomodulation, Middle Neovascularization, and Later Osteogenesis.
UPP1 promotes lung adenocarcinoma progression through the induction of an immunosuppressive microenvironment.
HDAC2 counteracts vascular calcification by activating autophagy in chronic kidney disease.
Retrospective identification of cell-intrinsic factors that mark pluripotency potential in rare somatic cells.
PMAIP1, a novel diagnostic and potential therapeutic biomarker in osteoporosis.
Dual effect of vitamin D(3) on breast cancer-associated fibroblasts.
Calcitriol promotes M2 polarization of tumor-associated macrophages in 4T1 mouse mammary gland cancer via the induction of proinflammatory cytokines.
CRP inhibits the osteoblastic differentiation of OPCs via the up-regulation of primary cilia and repression of the Hedgehog signaling pathway.
Self-Healing Micro Arc Oxidation and Dicalcium Phosphate Dihydrate Double-Passivated Coating on Magnesium Membrane for Enhanced Bone Integration Repair.
Integrative analysis unveils ECM signatures and pathways driving hepatocellular carcinoma progression: A multi-omics approach and prognostic model development.
Phytic acid promotes high glucose-mediated bone marrow mesenchymal stem cells osteogenesis via modulating circEIF4B that sponges miR-186-5p and complexes with IGF2BP3.
CGRP attenuates pulmonary vascular remodeling by inhibiting the cGAS-STING-NFκB pathway in pulmonary arterial hypertension.
Complex intrinsic abnormalities in osteoblast lineage cells of X-linked hypophosphatemia: Analysis of human iPS cell models generated by CRISPR/Cas9-mediated gene ablation.
Improving osseointegration and antimicrobial properties of titanium implants with black phosphorus nanosheets-hydroxyapatite composite coatings for vascularized bone regeneration.
Suramin inhibits phenotypic transformation of vascular smooth muscle cells and neointima hyperplasia by suppressing transforming growth factor beta receptor 1 /Smad2/3 pathway activation.
Single-Cell Transcriptional Profile Construction of Rat Pituitary Glands before and after Sexual Maturation and Identification of Novel Marker Spp1 in Gonadotropes.
Trimethylamine N-oxide Promotes Atherosclerosis by Regulating Low-Density Lipoprotein-Induced Autophagy in Vascular Smooth Muscle Cells Through PI3K/AKT/mTOR Pathway.
miR-145 Alleviates Smooth Muscle Cell Phenotype Transition via ADAM17-Mediated ACE2 Shedding.
Protective Effect of Alkaline Mineral Water on Calcium Oxalate-Induced Kidney Injury in Mice.
Therapeutic Effects of Mechanical Stress-Induced C2C12-Derived Exosomes on Glucocorticoid-Induced Osteoporosis Through miR-92a-3p/PTEN/AKT Signaling Pathway.
High-fat diet causes undesirable bone regeneration by altering the bone marrow environment in rats.
Ectomesenchymal Six1 controls mandibular skeleton formation.
S-propargyl-cysteine promotes the stability of atherosclerotic plaque via maintaining vascular muscle contractile phenotype.
Sustained delivery of osteogenic growth peptide through injectable photoinitiated composite hydrogel for osteogenesis.
Mir-142-5p inhibits the osteogenic differentiation of bone marrow mesenchymal stem cells by targeting Lhx8.
The response and resistance to drugs in ovarian cancer cell lines in 2D monolayers and 3D spheroids.
Effect of sulfonation time on physicochemical, osteogenic, antibacterial properties and biocompatibility of carbon fiber reinforced polyether ether ketone.
Milk-Derived Small Extracellular Vesicles Promote Osteogenic Differentiation and Inhibit Inflammation via microRNA-21.
Single-cell epigenome analysis identifies molecular events controlling direct conversion of human fibroblasts to pancreatic ductal-like cells.
A composite membrane with microtopographical morphology to regulate cellular behavior for improved tissue regeneration.
Inhibition of AT1R/IP3/IP3R-mediated Ca(2+) release protects against calcium oxalate crystals-induced renal oxidative stress.
A nano-conductive osteogenic hydrogel to locally promote calcium influx for electro-inspired bone defect regeneration.
lncRNA MEG3 Promotes Osteogenic Differentiation of Tendon Stem Cells Via the miR-129-5p/TCF4/β-Catenin Axis and thus Contributes to Trauma-Induced Heterotopic Ossification.
Ganoderma lucidum polysaccharide peptide (GLPP) attenuates rheumatic arthritis in rats through inactivating NF-κB and MAPK signaling pathways.
Sodium-glucose cotransporter 2 inhibitor canagliflozin alleviates vascular calcification through suppression of nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing-3 inflammasome.
The Wnt/β-catenin signaling pathway inhibits osteoporosis by regulating the expression of TERT: an in vivo and in vitro study.
Knockdown of Bach1 protects periodontal bone regeneration from inflammatory damage.
Impaired Growth Plate Maturation in XLH Is due to Both Excess FGF23 and Decreased 1,25-Dihydroxyvitamin D Signaling.
Melatonin-Primed Mesenchymal Stem Cells-Derived Small Extracellular Vesicles Alleviated Neurogenic Erectile Dysfunction by Reversing Phenotypic Modulation.
Apatinib remodels the immunosuppressive tumor ecosystem of gastric cancer enhancing anti-PD-1 immunotherapy.
Apolipoprotein E facilitates titanium implant osseointegration by regulating osteogenesis-lipogenesis balance.
Realizing Highly Efficient Sonodynamic Bactericidal Capability through the Phonon-Electron Coupling Effect Using Two-Dimensional Catalytic Planar Defects.
Mechanistic Insights into the Role of OPN in Mediating Brain Damage via Triggering Lysosomal Damage in Microglia/Macrophage.
Bioinspired Piezoelectric Periosteum to Augment Bone Regeneration via Synergistic Immunomodulation and Osteogenesis.
IL-1β contributes to the secretion of sclerostin by osteocytes and targeting sclerostin promotes spinal fusion at early stages.
FAM3A mediates the phenotypic switch of human aortic smooth muscle cells stimulated with oxidised low-density lipoprotein by influencing the PI3K-AKT pathway.
Bone microenvironment regulative hydrogels with ROS scavenging and prolonged oxygen-generating for enhancing bone repair.
Continuously released Zn(2+) in 3D-printed PLGA/β-TCP/Zn scaffolds for bone defect repair by improving osteoinductive and anti-inflammatory properties.
The marriage of immunomodulatory, angiogenic, and osteogenic capabilities in a piezoelectric hydrogel tissue engineering scaffold for military medicine.
Clock genes are expressed in cementum and regulate the proliferation and mineralization of cementoblasts.
Circular RNA CircSLC8A1 contributes to osteogenic differentiation in hBMSCs via CircSLC8A1/miR-144-3p/RUNX1 in periprosthetic osteolysis.
Single-cell RNA sequencing analysis revealed cellular and molecular immune profiles in lung squamous cell carcinoma.
A TEMPOL and rapamycin loaded nanofiber-covered stent favors endothelialization and mitigates neointimal hyperplasia and local inflammation.
Reversing the imbalance in bone homeostasis via sustained release of SIRT-1 agonist to promote bone healing under osteoporotic condition.
Calcium Phosphate Bone Cements Incorporated with Black Phosphorus Nanosheets Enhanced Osteogenesis.
Cannabidiol Rescues TNF-α-Inhibited Proliferation, Migration, and Osteogenic/Odontogenic Differentiation of Dental Pulp Stem Cells.
PKR deficiency delays vascular aging via inhibiting GSDMD-mediated endothelial cell hyperactivation.
Bta-miR-200b promotes endometrial epithelial cell apoptosis by targeting MYB in cattle.
Type 1 diabetes mellitus leads to gingivitis and an early compensatory increase in bone remodeling.
Metformin enhances the osteogenic activity of rat bone marrow mesenchymal stem cells by inhibiting oxidative stress induced by diabetes mellitus: an in vitro and in vivo study.
Ferroptotic stress facilitates smooth muscle cell dedifferentiation in arterial remodelling by disrupting mitochondrial homeostasis.
Macrophage migration inhibitory factor (MIF) inhibitor iSO-1 promotes staphylococcal protein A-induced osteogenic differentiation by inhibiting NF-κB signaling pathway.
Stimulus-Responsive Zwitterionic Prodrug Delivery System with Sustained Release of Hydrogen Sulfide for Protective Aortic Dissection.
Influence of FOSL1 Inhibition on Vascular Calcification and ROS Generation through Ferroptosis via P53-SLC7A11 Axis.
Retrospective identification of intrinsic factors that mark pluripotency potential in rare somatic cells.
Hypoxia Inhibits Cell Cycle Progression and Cell Proliferation in Brain Microvascular Endothelial Cells via the miR-212-3p/MCM2 Axis.
Co-overexpression of OPN, IGF-1 and CNTF augment the therapeutic effect of DPSC on spinal cord injury.
Engineered muscle from micro-channeled PEG scaffold with magnetic Fe(3)O(4) fixation towards accelerating esophageal muscle repair.
Overexpression of LOX-1 in hepatocytes protects vascular smooth muscle cells from phenotype transformation and wire injury induced carotid neoatherosclerosis through ALOX15.
CDN1163 alleviates SERCA2 dysfunction-induced pulmonary vascular remodeling by inhibiting the phenotypic transition of pulmonary artery smooth muscle cells.
Non-canonical function of histone methyltransferase G9a in the translational regulation of chronic inflammation.
The LRP5 high-bone-mass mutation causes alveolar bone accrual with minor craniofacial alteration.
Transcription factor 21 accelerates vascular calcification in mice by activating the IL-6/STAT3 signaling pathway and the interplay between VSMCs and ECs.
A Recombinant Parathyroid Hormone-Related Peptide Locally Applied in Osteoporotic Bone Defect.
miR-342-5p promotes vascular smooth muscle cell phenotypic transition through a negative-feedback regulation of Notch signaling via targeting FOXO3.
Changes in N6-methyladenosine RNA methylomes of human periodontal ligament cells in response to inflammatory conditions.
Nitration of cAMP-Response Element Binding Protein Participates in Myocardial Infarction-Induced Myocardial Fibrosis via Accelerating Transcription of Col1a2 and Cxcl12.
Identification of hub genes and pathways in lung metastatic colorectal cancer.
EMT-activated secretory and endocytic vesicular trafficking programs underlie a vulnerability to PI4K2A antagonism in lung cancer.
Osteopontin Promotes Macrophage M1 Polarization by Activation of the JAK1/STAT1/HMGB1 Signaling Pathway in Nonalcoholic Fatty Liver Disease.
Synergistic Effect of Magneto-Mechanical Bioengineered Stem Cells and Magnetic Field to Alleviate Osteoporosis.
BRG1 is involved in vascular calcification in chronic renal disease via autophagy of vascular smooth muscle cells.
Potential of an Aligned Porous Hydrogel Scaffold Combined with Periodontal Ligament Stem Cells or Gingival Mesenchymal Stem Cells to Promote Tissue Regeneration in Rat Periodontal Defects.
Biophysical Analysis and Preclinical Pharmacokinetics-Pharmacodynamics of Tangential Flow Filtration Fractionated Polymerized Human Hemoglobin as a Red Blood Cell Substitute.
Hsa_circRNA_0008028 Deficiency Ameliorates High Glucose-Induced Proliferation, Calcification, and Autophagy of Vascular Smooth Muscle Cells via miR-182-5p/TRIB3 Axis.
Preparation and Biocompatibility of Core-Shell Microspheres for Sequential, Sustained Release of BMP-2 and VEGF.
OPN Promotes Cell Proliferation and Invasion through NF-κB in Human Esophageal Squamous Cell Carcinoma.
Assessing serum levels of SM22α as a new biomarker for patients with aortic aneurysm/dissection.
Akkermansia muciniphila Alters Gut Microbiota and Immune System to Improve Cardiovascular Diseases in Murine Model.
Pan-Cancer Analysis of the Immunological Role of PDIA5: A Potential Target for Immunotherapy.
Hypoxia During the Consolidation Phase of Distraction Osteogenesis Promotes Bone Regeneration.
Pan-Cancer Analysis Reveals a Distinct Neutrophil Extracellular Trap-Associated Regulatory Pattern.
CCAAT/Enhancer-Binding Protein Alpha Is a Novel Regulator of Vascular Smooth Muscle Cell Osteochondrogenic Transition and Vascular Calcification.
TSH-SPP1/TRβ-TSH positive feedback loop mediates fat deposition of hepatocyte: Crosstalk between thyroid and liver.
Dissecting a hypoxia-related angiogenic gene signature for predicting prognosis and immune status in hepatocellular carcinoma.
Potassium Titanate Assembled Titanium Dioxide Nanotube Arrays Endow Titanium Implants Excellent Osseointegration Performance and Nerve Formation Potential.
Construction and osteogenic effects of 3D-printed porous titanium alloy loaded with VEGF/BMP-2 shell-core microspheres in a sustained-release system.
NRF2 is a critical regulator and therapeutic target of metal implant particle-incurred bone damage.
Negative pressure wound therapy improves bone regeneration by promoting osteogenic differentiation via the AMPK-ULK1-autophagy axis.
Dual Biosignal-Functional Injectable Microspheres for Remodeling Osteogenic Microenvironment.
Substitution of SERCA2 Cys(674) accelerates aortic aneurysm by inducing endoplasmic reticulum stress and promoting cell apoptosis.
The Protective Effects on Ischemia-Reperfusion Injury Mechanisms of the Thoracic Aorta in Daurian Ground Squirrels (Spermophilus dauricus) over the Torpor-Arousal Cycle of Hibernation.
Oxalate induces the ossification of RTECs by activating the JAK2/STAT3 signaling pathway and participates in the formation of kidney stones.
Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Enhance the Osteoblastic Differentiation of Periodontal Ligament Stem Cells Under High Glucose Conditions Through the PI3K/AKT Signaling Pathway.
Impact of Resolvin D1 on the inflammatory phenotype of periodontal ligament cell response to hypoxia.
LncRNA LINC00281/Annexin A2 Regulates Vascular Smooth Muscle Cell Phenotype Switching via the Nuclear Factor-Kappa B Signaling Pathway.
Gut microbiome dysbiosis contributes to abdominal aortic aneurysm by promoting neutrophil extracellular trap formation.
Iron overload-induced ferroptosis of osteoblasts inhibits osteogenesis and promotes osteoporosis: An in vitro and in vivo study.
Identification of osteopontin as a urinary biomarker for autosomal dominant polycystic kidney disease progression.
Fecal microbiota transplantation ameliorates bone loss in mice with ovariectomy-induced osteoporosis via modulating gut microbiota and metabolic function.
Niobium promotes fracture healing in rats by regulating the PI3K-Akt signalling pathway: An in vivo and in vitro study.
MiR-145 inhibits the differentiation and proliferation of bone marrow stromal mesenchymal stem cells by GABARAPL1 in steroid-induced femoral head necrosis.
CircZXDC Promotes Vascular Smooth Muscle Cell Transdifferentiation via Regulating miRNA-125a-3p/ABCC6 in Moyamoya Disease.
Decorin Promotes Osteoblastic Differentiation of Human Periodontal Ligament Stem Cells.
Salidroside protects against osteoporosis in ovariectomized rats by inhibiting oxidative stress and promoting osteogenesis via Nrf2 activation.
Carboxymethyl chitin or chitosan for osteoinduction effect on the human periodontal ligament stem cells.
Intraoperative Hypothermia Induces Vascular Dysfunction in the CA1 Region of Rat Hippocampus.
Mussel-inspired multifunctional surface through promoting osteogenesis and inhibiting osteoclastogenesis to facilitate bone regeneration.
STARD3NL inhibits the osteogenic differentiation by inactivating the Wnt/β-catenin pathway via binding to Annexin A2 in osteoporosis.
Molecular feature of arterial remodeling in the brain arteriovenous malformation revealed by arteriovenous shunt rat model and RNA sequencing.
MicroRNA-27a-3p inhibits lung and skin fibrosis of systemic sclerosis by negatively regulating SPP1.
Iron deficiency exacerbates aortic medial degeneration by inducing excessive mitochondrial fission.
Semaphorin3A promotes osseointegration of titanium implants in osteoporotic rabbits.
Increased expression of osteopontin in subchondral bone promotes bone turnover and remodeling, and accelerates the progression of OA in a mouse model.
SIRT6 protects vascular smooth muscle cells from osteogenic transdifferentiation via Runx2 in chronic kidney disease.
Development of Intracorporeal Differentiation of Stem Cells to Induce One-Step Mastoid Bone Reconstruction during Otitis Media Surgeries.
Osteopontin expression in the invasive front stroma of colorectal adenocarcinoma is associated with tumor budding and prognosis.
Dickkopf1 (Dkk1) Alleviates Vascular Calcification by Regulating the Degradation of Phospholipase D1 (PLD1).
Halide-containing bioactive glasses enhance osteogenesis in vitro and in vivo.
PVT1/miR-145-5p/HK2 modulates vascular smooth muscle cells phenotype switch via glycolysis: The new perspective on the spiral artery remodeling.
Mesoporous Silica Promotes Osteogenesis of Human Adipose-Derived Stem Cells Identified by a High-Throughput Microfluidic Chip Assay.
Electroactive Hydroxyapatite/Carbon Nanofiber Scaffolds for Osteogenic Differentiation of Human Adipose-Derived Stem Cells.
Multi-Transcriptomic Analysis Reveals the Heterogeneity and Tumor-Promoting Role of SPP1/CD44-Mediated Intratumoral Crosstalk in Gastric Cancer.
Icariin Treatment Rescues Diabetes Induced Bone Loss via Scavenging ROS and Activating Primary Cilia/Gli2/Osteocalcin Signaling Pathway.
Circular RNA BIRC6 depletion promotes osteogenic differentiation of periodontal ligament stem cells via the miR-543/PTEN/PI3K/AKT/mTOR signaling pathway in the inflammatory microenvironment.
The Annexin A2-Notch regulatory loop in hepatocytes promotes liver fibrosis in NAFLD by increasing osteopontin expression.
Cinnamaldehyde protects against ligature-induced periodontitis through the inhibition of microbial accumulation and inflammatory responses of host immune cells.
Immunohistochemical expression of osteopontin and collagens in choroid plexus of human brains.
N-acetylcysteine promotes cyclic mechanical stress-induced osteogenic differentiation of periodontal ligament stem cells by down-regulating Nrf2 expression.
Bmal1 promotes cementoblast differentiation and cementum mineralization via Wnt/β-catenin signaling.
Decoding the temporal and regional specification of microglia in the developing human brain.
ELAV-like RNA binding protein 1 regulates osteogenesis in diabetic osteoporosis: Involvement of divalent metal transporter 1.
Role of (pro)renin receptor in cyclosporin A-induced nephropathy.
Bioinformatics analysis of laryngeal squamous cell carcinoma: seeking key candidate genes and pathways.
Nrf2 Activation Is Involved in Cyclic Mechanical Stress-Stimulated Osteogenic Differentiation in Periodontal Ligament Stem Cells via PI3K/Akt Signaling and HO1-SOD2 Interaction.
Cyclic Distraction-Compression Dynamization Technique Enhances the Bone Formation During Distraction Osteogenesis.
Long Non-coding RNAs LOC100126784 and POM121L9P Derived From Bone Marrow Mesenchymal Stem Cells Enhance Osteogenic Differentiation via the miR-503-5p/SORBS1 Axis.
FBS-Derived Exosomes as a Natural Nano-Scale Carrier for Icariin Promote Osteoblast Proliferation.
PRDX2 Protects Against Atherosclerosis by Regulating the Phenotype and Function of the Vascular Smooth Muscle Cell.
Metformin Inhibits Abdominal Aortic Aneurysm Formation through the Activation of the AMPK/mTOR Signaling Pathway.
Quantitative Proteomics Reveals the Dynamic Pathophysiology Across Different Stages in a Rat Model of Severe Traumatic Brain Injury.
Dura cells in the etiopathogenesis of Crouzon syndrome: the effects of FGFR2 mutations in the dura cells on the proliferation of osteoblasts through the hippo/YAP mediated transcriptional regulation pathway.
Identification and Validation of a Tumor Microenvironment-Related Gene Signature in Hepatocellular Carcinoma Prognosis.
Identification of VWF as a Novel Biomarker in Lung Adenocarcinoma by Comprehensive Analysis.
Exogenous H(2) S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
Biomimetic Cell-Substrate of Chitosan-Cross-linked Polyaniline Patterning on TiO(2) Nanotubes Enables hBM-MSCs to Differentiate the Osteoblast Cell Type.
Polydopamine-Coated Poly(l-lactide) Nanofibers with Controlled Release of VEGF and BMP-2 as a Regenerative Periosteum.
Association of urinary ketamine and APOA1 levels with bladder dysfunction in ketamine abusers revealed via proteomics and targeted metabolite analyses.
ET(A)R silencing ameliorated neurovascular injury after SAH in rats through ERK/KLF4-mediated phenotypic transformation of smooth muscle cells.
Primary cilia regulate gastric cancer-induced bone loss via cilia/Wnt/β-catenin signaling pathway.
Inactivation of SERCA2 Cys(674) accelerates aortic aneurysms by suppressing PPARγ.
Long-lasting renewable antibacterial porous polymeric coatings enable titanium biomaterials to prevent and treat peri-implant infection.
Nrf2 activation is involved in osteogenic differentiation of periodontal ligament stem cells under cyclic mechanical stretch.
The preventive and therapeutic effects of AAV1-KLF4-shRNA in cigarette smoke-induced pulmonary hypertension.
A protumorigenic secretory pathway activated by p53 deficiency in lung adenocarcinoma.
A Dual Role of Heme Oxygenase-1 in Angiotensin II-Induced Abdominal Aortic Aneurysm in the Normolipidemic Mice.
Significance of MR/OPN/HMGB1 axis in NAFLD-associated hepatic fibrogenesis.
lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.
Prostacyclin facilitates vascular smooth muscle cell phenotypic transformation via activating TP receptors when IP receptors are deficient.
MSCs-extracellular vesicles attenuated neuroinflammation, synapse damage and microglial phagocytosis after hypoxia-ischemia injury by preventing osteopontin expression.
MicroRNA-520c-3p targeting of RelA/p65 suppresses atherosclerotic plaque formation.
Polypeptides IGF-1C and P24 synergistically promote osteogenic differentiation of bone marrow mesenchymal stem cells in vitro through the p38 and JNK signaling pathways.
Geniposide Ameliorated Dexamethasone-Induced Cholesterol Accumulation in Osteoblasts by Mediating the GLP-1R/ABCA1 Axis.
Establishment and characterization of a highly metastatic human osteosarcoma cell line from osteosarcoma lung metastases.
Polo Like Kinase 4 (PLK4) impairs human bone marrow mesenchymal stem cell (BMSC) viability and osteogenic differentiation.
Higher BMP Expression in Tendon Stem/Progenitor Cells Contributes to the Increased Heterotopic Ossification in Achilles Tendon With Aging.
Piperlongumine Attenuates High Calcium/Phosphate-Induced Arterial Calcification by Preserving P53/PTEN Signaling.
Ethyl Acetate Fraction from Hedyotis diffusa plus Scutellaria barbata Suppresses Migration of Bone-Metastatic Breast Cancer Cells via OPN-FAK/ERK/NF-κB Axis.
OPN Deficiency Increases the Severity of Osteoarthritis Associated with Aberrant Chondrocyte Senescence and Apoptosis and Upregulates the Expression of Osteoarthritis-Associated Genes.
R-Spondin 2 Induces Odontogenic Differentiation of Dental Pulp Stem/Progenitor Cells via Regulation of Wnt/β-Catenin Signaling.
Ginsenoside Rg3 attenuates ovariectomy-induced osteoporosis via AMPK/mTOR signaling pathway.
RNA-seq analysis of palatal transcriptome changes in all-trans retinoic acid-induced cleft palate of mice.
Novel gene-specific translation mechanism of dysregulated, chronic inflammation reveals promising, multifaceted COVID-19 therapeutics.
T-cell death-associated gene 8 accelerates atherosclerosis by promoting vascular smooth muscle cell proliferation and migration.
Exercise Promotes the Osteoinduction of HA/β-TCP Biomaterials via the Wnt Signaling Pathway.
Cortistatin ameliorates Ang II-induced proliferation of vascular smooth muscle cells by inhibiting autophagy through SSTR3 and SSTR5.
Quantitative alterations in bovine milk proteome from healthy, subclinical and clinical mastitis during S. aureus infection.
Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function.
The effect of extracellular matrix on the differentiation of mouse embryonic stem cells.
SHED-derived conditioned exosomes enhance the osteogenic differentiation of PDLSCs via Wnt and BMP signaling in vitro.
Activation of cannabinoid receptor type 2-induced osteogenic differentiation involves autophagy induction and p62-mediated Nrf2 deactivation.
Modulation of the mechanosensing of mesenchymal stem cells by laser-induced patterning for the acceleration of tissue reconstruction through the Wnt/β-catenin signaling pathway activation.
P38 MAPK signaling pathway mediates COM crystal-induced crystal adhesion change in rat renal tubular epithelial cells.
Semaphorin 3A-hypoxia inducible factor 1 subunit alpha co-overexpression enhances the osteogenic differentiation of induced pluripotent stem cells-derived mesenchymal stem cells in vitro.
PKM2 suppresses osteogenesis and facilitates adipogenesis by regulating β-catenin signaling and mitochondrial fusion and fission.
Sustained delivery of PlGF-2(123-144*)-fused BMP2-related peptide P28 from small intestinal submucosa/polylactic acid scaffold material for bone tissue regeneration.
Daphnetin ameliorates glucocorticoid-induced osteoporosis via activation of Wnt/GSK-3β/β-catenin signaling.
Smooth muscle NADPH oxidase 4 promotes angiotensin II-induced aortic aneurysm and atherosclerosis by regulating osteopontin.
Biomineralizaion of hydroxyapatite on polyethylene terephthalate artificial ligaments promotes graft-bone healing after anterior cruciate ligament reconstruction: An in vitro and in vivo study.
AKT/FOXO1 axis links cross-talking of endothelial cell and pericyte in TIE2-mutated venous malformations.
Effect of interleukin-33 on cementoblast-mediated cementum repair during orthodontic tooth movement.
A novel Sprouty4-ERK1/2-Wnt/β-catenin regulatory loop in marrow stromal progenitor cells controls osteogenic and adipogenic differentiation.
Icariin Protects Bone Marrow Mesenchymal Stem Cells Against Iron Overload Induced Dysfunction Through Mitochondrial Fusion and Fission, PI3K/AKT/mTOR and MAPK Pathways.
2,3,7,8-Tetrachlorodibenzo-p-dioxin promotes injury-induced vascular neointima formation in mice.
Inhibiting effect of microRNA-187-3p on osteogenic differentiation of osteoblast precursor cells by suppressing cannabinoid receptor type 2.
Incorporated-bFGF polycaprolactone/polyvinylidene fluoride nanocomposite scaffold promotes human induced pluripotent stem cells osteogenic differentiation.
SPARC induces phenotypic modulation of human brain vascular smooth muscle cells via AMPK/mTOR-mediated autophagy.
Osteopontin in the Pathogenesis of Aortic Dissection by the Enhancement of MMP Expressions.
Citric acid enhances the physical properties, cytocompatibility and osteogenesis of magnesium calcium phosphate cement.
The role and mechanism of transforming growth factor beta 3 in human myocardial infarction-induced myocardial fibrosis.
Small molecule inhibitor of TGF-β signaling enables robust osteogenesis of autologous GMSCs to successfully repair minipig severe maxillofacial bone defects.
Adipose-derived stem cells-conditioned medium improved osteogenic differentiation of induced pluripotent stem cells when grown on polycaprolactone nanofibers.
Peroxisome Proliferator-Activated Receptor-γ Coactivator-1α Inhibits Vascular Calcification Through Sirtuin 3-Mediated Reduction of Mitochondrial Oxidative Stress.
Circulating osteopontin per tumor volume as a prognostic biomarker for resectable intrahepatic cholangiocarcinoma.
Effect of Hydroxyapatite Nanorods on the Fate of Human Adipose-Derived Stem Cells Assessed In Situ at the Single Cell Level with a High-Throughput, Real-Time Microfluidic Chip.
Study of Bone Regeneration and Osteointegration Effect of a Novel Selective Laser-Melted Titanium-Tantalum-Niobium-Zirconium Alloy Scaffold.
Efficient osteogenic differentiation of the dental pulp stem cells on β-glycerophosphate loaded polycaprolactone/polyethylene oxide blend nanofibers.
Quantitative proteomics of milk whey reveals breed and season specific variation in protein abundance in Holstein Friesian cow and Murrah buffalo.
Effect of microRNA-21 on hypoxia-inducible factor-1α in orthodontic tooth movement and human periodontal ligament cells under hypoxia.
Promoting osteogenic differentiation of human-induced pluripotent stem cells by releasing Wnt/β-catenin signaling activator from the nanofibers.
Validation of Phosphodiesterase-10 as a Novel Target for Pulmonary Arterial Hypertension via Highly Selective and Subnanomolar Inhibitors.
New Application of Psoralen and Angelicin on Periodontitis With Anti-bacterial, Anti-inflammatory, and Osteogenesis Effects.
Downregulated Expression of Solute Carrier Family 26 Member 6 in NRK-52E Cells Attenuates Oxalate-Induced Intracellular Oxidative Stress.
Osteopontin is essential for IL-1β production and apoptosis in peri-implantitis.
Hypoxia-Inducible Factor-1α (HIF-1α) Expression on Endothelial Cells in Juvenile Nasopharyngeal Angiofibroma: A Review of 70 cases and Tissue Microarray Analysis.
Nesfatin-1 promotes VSMC migration and neointimal hyperplasia by upregulating matrix metalloproteinases and downregulating PPARγ.
Negative pressure wound therapy promotes muscle-derived stem cell osteogenic differentiation through MAPK pathway.
Teniposide regulates the phenotype switching of vascular smooth muscle cells in a miR-21-dependent manner.
Myricetin ameliorates glucocorticoid-induced osteoporosis through the ERK signaling pathway.
Osteopontin contributes to effective neutrophil recruitment, IL-1β production and apoptosis in Aspergillus fumigatus keratitis.
The prognostic value of osteopontin in limited-stage small cell lung cancer patients and its mechanism.
The protective effect of PFTα on alcohol-induced osteonecrosis of the femoral head.
MgAl layered double hydroxide/chitosan porous scaffolds loaded with PFTα to promote bone regeneration.
SC79-loaded ZSM-5/chitosan porous scaffolds with enhanced stem cell osteogenic differentiation and bone regeneration.
Microarray-based detection and expression analysis of new genes associated with drug resistance in ovarian cancer cell lines.
Transcriptome analysis in primary colorectal cancer tissues from patients with and without liver metastases using next-generation sequencing.
MicroRNA-99a inhibits insulin-induced proliferation, migration, dedifferentiation, and rapamycin resistance of vascular smooth muscle cells by inhibiting insulin-like growth factor-1 receptor and mammalian target of rapamycin.
Interleukin-6 enhances cancer stemness and promotes metastasis of hepatocellular carcinoma via up-regulating osteopontin expression.
Intrarenal macrophage infiltration induced by T cells is associated with podocyte injury in lupus nephritis patients.
Comparative investigation of human amniotic epithelial cells and mesenchymal stem cells for application in bone tissue engineering.
The chemokine CXCL13 in lung cancers associated with environmental polycyclic aromatic hydrocarbons pollution.
Serum anti-osteopontin autoantibody as a novel diagnostic and prognostic biomarker in patients with hepatocellular carcinoma.
Protective effects of epigallocatechin gallate (EGCG) on streptozotocin-induced diabetic nephropathy in mice.
Characterization of a micro-roughened TiO2/ZrO2 coating: mechanical properties and HBMSC responses in vitro.
Osteogenic differentiation of human amniotic epithelial cells and its application in alveolar defect restoration.
Wu X, Xia Y, Dai H, Hong C, Zhao Y, Wei W, Zheng D
Advanced healthcare materials 2024 Sep;13(22):e2400770
Advanced healthcare materials 2024 Sep;13(22):e2400770
Bioactive peptide relieves glucocorticoid-induced osteoporosis by giant macrocyclic encapsulation.
Shang Y, Zhu Q, Ding J, Zhao L, Zhang F, Lu J, Feng Y, Wang J, Liu Z, Kuang M, Li C
Journal of controlled release : official journal of the Controlled Release Society 2024 May;369:75-87
Journal of controlled release : official journal of the Controlled Release Society 2024 May;369:75-87
Urchin-like multiscale structured fluorinated hydroxyapatite as versatile filler for caries restoration dental resin composites.
Zhang S, Wang X, Yin S, Wang J, Chen H, Jiang X
Bioactive materials 2024 May;35:477-494
Bioactive materials 2024 May;35:477-494
CNPY2 governs PDGF‑BB‑treated vascular smooth muscle cell proliferation, migration and phenotypic transformation via the Akt/mTOR/GSK‑3β signaling pathway.
Sun H, Wang X, Ma L, Li X, Jin W, Yang Y
Experimental and therapeutic medicine 2024 May;27(5):197
Experimental and therapeutic medicine 2024 May;27(5):197
Asprosin aggravates atherosclerosis via regulating the phenotype transformation of vascular smooth muscle cells.
Zhao Y, Wang Z, Chen Y, Feng M, Liu X, Chen H, Wang N, Wang Z, Cao S, Ren J, Liu X, Zhao Y, Zhang Y
International journal of biological macromolecules 2024 May;268(Pt 2):131868
International journal of biological macromolecules 2024 May;268(Pt 2):131868
Multifunctional tannic acid-based nanocomposite methacrylated silk fibroin hydrogel with the ability to scavenge reactive oxygen species and reduce inflammation for bone regeneration.
Wang R, He X, Su S, Bai J, Liu H, Zhou F
International journal of biological macromolecules 2024 May;266(Pt 2):131357
International journal of biological macromolecules 2024 May;266(Pt 2):131357
Injectable, anti-collapse, adhesive, plastic and bioactive bone graft substitute promotes bone regeneration by moderating oxidative stress in osteoporotic bone defect.
Huang L, Zhang S, Bian M, Xiang X, Xiao L, Wang J, Lu S, Chen W, Zhang C, Mo G, Jiang L, Li Y, Zhang J
Acta biomaterialia 2024 May;180:82-103
Acta biomaterialia 2024 May;180:82-103
An integrated multi-omics analysis reveals osteokines involved in global regulation.
Liang W, Wei T, Hu L, Chen M, Tong L, Zhou W, Duan X, Zhao X, Zhou W, Jiang Q, Xiao G, Zou W, Chen D, Zou Z, Bai X
Cell metabolism 2024 May 7;36(5):1144-1163.e7
Cell metabolism 2024 May 7;36(5):1144-1163.e7
Fibrous periosteum repairs bone fracture and maintains the healed bone throughout mouse adulthood.
Liu YL, Tang XT, Shu HS, Zou W, Zhou BO
Developmental cell 2024 May 6;59(9):1192-1209.e6
Developmental cell 2024 May 6;59(9):1192-1209.e6
Activation of CaMKII/HDAC4 by SDF1 contributes to pulmonary arterial hypertension via stabilization Runx2.
Chen Y, Liu J, Zhang Q, Chai L, Chen H, Li D, Wang Y, Qiu Y, Shen N, Zhang J, Wang Q, Wang J, Xie X, Li S, Li M
European journal of pharmacology 2024 May 5;970:176483
European journal of pharmacology 2024 May 5;970:176483
Carbonylation of Runx2 at K176 by 4-Hydroxynonenal Accelerates Vascular Calcification.
Zhai X, Cao S, Wang J, Qiao B, Liu X, Hua R, Zhao M, Sun S, Han Y, Wu S, Pang J, Yuan Q, Wang B, Xu F, Wei S, Chen Y
Circulation 2024 May 28;149(22):1752-1769
Circulation 2024 May 28;149(22):1752-1769
Targeting osteopontin alleviates endometriosis and inflammation by inhibiting the RhoA/ROS axis and achieves non-invasive in vitro detection via menstrual blood.
Wang H, Wang B, Wu M, Lu J, Duan P
Human reproduction (Oxford, England) 2024 May 2;39(5):1057-1071
Human reproduction (Oxford, England) 2024 May 2;39(5):1057-1071
Murine double minute 2-mediated estrogen receptor 1 degradation activates macrophage migration inhibitory factor to promote vascular smooth muscle cell dedifferentiation and oxidative stress during thoracic aortic aneurysm progression.
Liu T, Zhang T, Guo C, Liang X, Wang P, Zheng B
Biochimica et biophysica acta. Molecular cell research 2024 Mar;1871(3):119661
Biochimica et biophysica acta. Molecular cell research 2024 Mar;1871(3):119661
Identification of SLC2A1 as a predictive biomarker for survival and response to immunotherapy in lung squamous cell carcinoma.
Hao B, Dong H, Xiong R, Song C, Xu C, Li N, Geng Q
Computers in biology and medicine 2024 Mar;171:108183
Computers in biology and medicine 2024 Mar;171:108183
Hypermethylation of Bmp2 and Fgfr2 Promoter Regions in Bone Marrow Mesenchymal Stem Cells Leads to Bone Loss in Prematurely Aged Mice.
Wang Y, Sun L, Kan T, Xue W, Wang H, Xu P, Zhang L, Yan M, Li H, Yu Z
Aging and disease 2024 Mar 29;
Aging and disease 2024 Mar 29;
Mechanism of Porphyra Yezoensis Polysaccharides in Inhibiting Hyperoxalate-Induced Renal Injury and Crystal Deposition.
Deng JW, Li CY, Huang YP, Liu WF, Zhang Q, Long J, Wu WQ, Huang LH, Zeng GH, Sun XY
Journal of agricultural and food chemistry 2024 Mar 27;72(12):6372-6388
Journal of agricultural and food chemistry 2024 Mar 27;72(12):6372-6388
Single-cell RNA sequencing reveals epithelial cells driving brain metastasis in lung adenocarcinoma.
Wu Y, Yang F, Luo S, Li X, Gu Z, Fan R, Cao Y, Wang L, Song X
iScience 2024 Mar 15;27(3):109258
iScience 2024 Mar 15;27(3):109258
Resolvin D1 attenuates Ang II-induced hypertension in mice by inhibiting the proliferation, migration and phenotypic transformation of vascular smooth muscle cells by blocking the RhoA/mitogen-activated protein kinase pathway.
Wei C, Zhang J, Peng S, Liu J, Xu Y, Zhao M, Xu S, Pan W, Yin Z, Zheng Z, Qin JJ, Wan J, Wang M
Journal of hypertension 2024 Mar 1;42(3):420-431
Journal of hypertension 2024 Mar 1;42(3):420-431
HOXB9 promotes osteosarcoma cell survival and malignancy under glucose starvation via upregulating SPP1 expression.
Han J, Ji R, Zheng S, Xia X, Du W, He H, Han C, Zhao W, Li X, Wang Y, Zhang L
Biochemical pharmacology 2024 Jun;224:116208
Biochemical pharmacology 2024 Jun;224:116208
Integrated bioinformatics analysis identified leucine rich repeat containing 15 and secreted phosphoprotein 1 as hub genes for calcific aortic valve disease and osteoarthritis.
Gong S, Xiang K, Chen L, Zhuang H, Song Y, Chen J
IET systems biology 2024 Jun;18(3):77-91
IET systems biology 2024 Jun;18(3):77-91
SPP1 could be an immunological and prognostic biomarker: From pan-cancer comprehensive analysis to osteosarcoma validation.
Zhang Z, Liu B, Lin Z, Mei L, Chen R, Li Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 31;38(14):e23783
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 31;38(14):e23783
Single-Cell RNA Transcriptome of the Human Endometrium Reveals Epithelial Characterizations Associated with Recurrent Implantation Failure.
Zhang H, Zhang C, Zhang S
Advanced biology 2024 Jan;8(1):e2300110
Advanced biology 2024 Jan;8(1):e2300110
KLF2/PPARγ axis contributes to trauma-induced heterotopic ossification by regulating mitochondrial dysfunction.
Sun Z, Liu H, Hu Y, Luo G, Yuan Z, Liu W, Tu B, Ruan H, Li J, Fan C
Cell proliferation 2024 Jan;57(1):e13521
Cell proliferation 2024 Jan;57(1):e13521
Myeloid-derived growth factor suppresses VSMC dedifferentiation and attenuates postinjury neointimal formation in rats by activating S1PR2 and its downstream signaling.
Yang S, Li HW, Tian JY, Wang ZK, Chen Y, Zhan TT, Ma CY, Feng M, Cao SF, Zhao Y, Li X, Ren J, Liu Q, Jin LY, Wang ZQ, Jiang WY, Zhao YX, Zhang Y, Liu X
Acta pharmacologica Sinica 2024 Jan;45(1):98-111
Acta pharmacologica Sinica 2024 Jan;45(1):98-111
Isoliquiritin treatment of osteoporosis by promoting osteogenic differentiation and autophagy of bone marrow mesenchymal stem cells.
Su Z, Chen D, Huang J, Liang Z, Ren W, Zhang Z, Jiang Q, Luo T, Guo L
Phytotherapy research : PTR 2024 Jan;38(1):214-230
Phytotherapy research : PTR 2024 Jan;38(1):214-230
3D-printed tri-element-doped hydroxyapatite/ polycaprolactone composite scaffolds with antibacterial potential for osteosarcoma therapy and bone regeneration.
Huang H, Qiang L, Fan M, Liu Y, Yang A, Chang D, Li J, Sun T, Wang Y, Guo R, Zhuang H, Li X, Guo T, Wang J, Tan H, Zheng P, Weng J
Bioactive materials 2024 Jan;31:18-37
Bioactive materials 2024 Jan;31:18-37
Carp scales derived double cross-linking hydrogels achieve collagen peptides sustained-released for bone regeneration.
Zheng F, Ju M, Lü Y, Hua Y, Yao W, Wu H, Zhao M, Han S, Wei Y, Liu R
International journal of biological macromolecules 2024 Jan;255:128276
International journal of biological macromolecules 2024 Jan;255:128276
A novel lncRNA GM15416 regulates osteoblast apoptosis and differentiation through the c-Fos/Fas axis and mitigates osteoporosis.
Zhao D, He J, Zhao X, Sheng X, Feng Z, Wang X, Zhang C, Wang S, Geng B, Xia Y
International journal of biological macromolecules 2024 Jan;254(Pt 2):127824
International journal of biological macromolecules 2024 Jan;254(Pt 2):127824
S-adenosylmethionine attenuates angiotensin II-induced aortic dissection formation by inhibiting vascular smooth muscle cell phenotypic switch and autophagy.
Shen X, Xie X, Wu Q, Shi F, Chen Y, Yuan S, Xing K, Li X, Zhu Q, Li B, Wang Z
Biochemical pharmacology 2024 Jan;219:115967
Biochemical pharmacology 2024 Jan;219:115967
Regulation of the immune microenvironment by pioglitazone-loaded polylactic glycolic acid nanosphere composite scaffolds to promote vascularization and bone regeneration.
Fan S, Tan Y, Yuan X, Liu C, Wu X, Dai T, Ni S, Wang J, Weng Y, Zhao H
Journal of tissue engineering 2024 Jan-Dec;15:20417314241231452
Journal of tissue engineering 2024 Jan-Dec;15:20417314241231452
Nanoscaled Titanium Oxide Layer Provokes Quick Osseointegration on 3D-Printed Dental Implants: A Domino Effect Induced by Hydrophilic Surface.
Shu T, Wang X, Li M, Ma S, Cao J, Sun G, Lai T, Liu S, Li A, Qu Z, Pei D
ACS nano 2024 Jan 9;18(1):783-797
ACS nano 2024 Jan 9;18(1):783-797
Single-cell profiling of the microenvironment in human bone metastatic renal cell carcinoma.
Ma F, Wang S, Xu L, Huang W, Shi G, Sun Z, Cai W, Wu Z, Huang Y, Meng J, Sun Y, Fang M, Cheng M, Ji Y, Hu T, Zhang Y, Gu B, Zhang J, Song S, Sun Y, Yan W
Communications biology 2024 Jan 12;7(1):91
Communications biology 2024 Jan 12;7(1):91
PRMT3 methylates HIF-1α to enhance the vascular calcification induced by chronic kidney disease.
Zhou G, Zhang C, Peng H, Su X, Huang Q, Zhao Z, Zhao G
Molecular medicine (Cambridge, Mass.) 2024 Jan 10;30(1):8
Molecular medicine (Cambridge, Mass.) 2024 Jan 10;30(1):8
Alamandine attenuates ovariectomy-induced osteoporosis by promoting osteogenic differentiation via AMPK/eNOS axis.
Luo W, Yao C, Sun J, Zhang B, Chen H, Miao J, Zhang Y
BMC musculoskeletal disorders 2024 Jan 10;25(1):45
BMC musculoskeletal disorders 2024 Jan 10;25(1):45
Nerve growth factor promote osteogenic differentiation of dental pulp stem cells through MEK/ERK signalling pathways.
Cheng C, Tang S, Cui S, Yang T, Li L, Zhai M, Wei F, Ding G
Journal of cellular and molecular medicine 2024 Feb;28(4):e18143
Journal of cellular and molecular medicine 2024 Feb;28(4):e18143
Biomimetic cryogel promotes the repair of osteoporotic bone defects through altering the ROS niche via down-regulating the ROMO1.
Liu H, Pan W, Liu H, Xie D, Liao L
International journal of biological macromolecules 2024 Feb;257(Pt 1):128481
International journal of biological macromolecules 2024 Feb;257(Pt 1):128481
A multifunctional quercetin/polycaprolactone electrospun fibrous membrane for periodontal bone regeneration.
Hu Y, Fu Z, Yang S, Zhou Y, Zhu H, Zhu Y, Zhou J, Lin K, Xu Y
Materials today. Bio 2024 Feb;24:100906
Materials today. Bio 2024 Feb;24:100906
Coenzyme Q10 Protects Against Hyperlipidemia-Induced Osteoporosis by Improving Mitochondrial Function via Modulating miR-130b-3p/PGC-1α Pathway.
Meng M, Wang J, Wang C, Zhao J, Wang H, Zhang Y, Sun H, Liu M
Calcified tissue international 2024 Feb;114(2):182-199
Calcified tissue international 2024 Feb;114(2):182-199
Three Birds, One Stone: An Osteo-Microenvironment Stage-Regulative Scaffold for Bone Defect Repair through Modulating Early Osteo-Immunomodulation, Middle Neovascularization, and Later Osteogenesis.
Yuan Y, Xu Y, Mao Y, Liu H, Ou M, Lin Z, Zhao R, Long H, Cheng L, Sun B, Zhao S, Zeng M, Lu B, Lu H, Zhu Y, Chen C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(6):e2306428
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(6):e2306428
UPP1 promotes lung adenocarcinoma progression through the induction of an immunosuppressive microenvironment.
Li Y, Jiang M, Aye L, Luo L, Zhang Y, Xu F, Wei Y, Peng D, He X, Gu J, Yu X, Li G, Ge D, Lu C
Nature communications 2024 Feb 8;15(1):1200
Nature communications 2024 Feb 8;15(1):1200
HDAC2 counteracts vascular calcification by activating autophagy in chronic kidney disease.
Zhou G, Liu P, Zhang C, Huang Q, Zhao Z, Wu S, Li D, Liu H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Feb 29;38(4):e23470
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Feb 29;38(4):e23470
Retrospective identification of cell-intrinsic factors that mark pluripotency potential in rare somatic cells.
Jain N, Goyal Y, Dunagin MC, Cote CJ, Mellis IA, Emert B, Jiang CL, Dardani IP, Reffsin S, Arnett M, Yang W, Raj A
Cell systems 2024 Feb 21;15(2):109-133.e10
Cell systems 2024 Feb 21;15(2):109-133.e10
PMAIP1, a novel diagnostic and potential therapeutic biomarker in osteoporosis.
Li T, Yuan J, Xu P, Jia J, Zhao J, Zhang J, Ding R, Zhao X, He D, Wu T, Cheng X
Aging 2024 Feb 16;16(4):3694-3715
Aging 2024 Feb 16;16(4):3694-3715
Dual effect of vitamin D(3) on breast cancer-associated fibroblasts.
Łabędź N, Anisiewicz A, Stachowicz-Suhs M, Banach J, Kłopotowska D, Maciejczyk A, Gazińska P, Piotrowska A, Dzięgiel P, Matkowski R, Wietrzyk J
BMC cancer 2024 Feb 15;24(1):209
BMC cancer 2024 Feb 15;24(1):209
Calcitriol promotes M2 polarization of tumor-associated macrophages in 4T1 mouse mammary gland cancer via the induction of proinflammatory cytokines.
Stachowicz-Suhs M, Łabędź N, Anisiewicz A, Banach J, Kłopotowska D, Milczarek M, Piotrowska A, Dzięgiel P, Maciejczyk A, Matkowski R, Wietrzyk J
Scientific reports 2024 Feb 15;14(1):3778
Scientific reports 2024 Feb 15;14(1):3778
CRP inhibits the osteoblastic differentiation of OPCs via the up-regulation of primary cilia and repression of the Hedgehog signaling pathway.
Xu J, Wu X, Zhu H, Zhu Y, Du K, Deng X, Wang C
Medical oncology (Northwood, London, England) 2024 Feb 12;41(3):72
Medical oncology (Northwood, London, England) 2024 Feb 12;41(3):72
Self-Healing Micro Arc Oxidation and Dicalcium Phosphate Dihydrate Double-Passivated Coating on Magnesium Membrane for Enhanced Bone Integration Repair.
Wu J, Shen Y, Wang P, Guo Z, Bai J, Wang X, Chen D, Lin X, Tang C
ACS biomaterials science & engineering 2024 Feb 12;10(2):1062-1076
ACS biomaterials science & engineering 2024 Feb 12;10(2):1062-1076
Integrative analysis unveils ECM signatures and pathways driving hepatocellular carcinoma progression: A multi-omics approach and prognostic model development.
Liu Z, Zhao P
Journal of cellular and molecular medicine 2024 Apr;28(8):e18230
Journal of cellular and molecular medicine 2024 Apr;28(8):e18230
Phytic acid promotes high glucose-mediated bone marrow mesenchymal stem cells osteogenesis via modulating circEIF4B that sponges miR-186-5p and complexes with IGF2BP3.
Wu J, Li X, Nie H, Shen Y, Guo Z, Huihan Chu C, Cai K, Tang C
Biochemical pharmacology 2024 Apr;222:116118
Biochemical pharmacology 2024 Apr;222:116118
CGRP attenuates pulmonary vascular remodeling by inhibiting the cGAS-STING-NFκB pathway in pulmonary arterial hypertension.
Yan X, Huang J, Zeng Y, Zhong X, Fu Y, Xiao H, Wang X, Lian H, Luo H, Li D, Guo R
Biochemical pharmacology 2024 Apr;222:116093
Biochemical pharmacology 2024 Apr;222:116093
Complex intrinsic abnormalities in osteoblast lineage cells of X-linked hypophosphatemia: Analysis of human iPS cell models generated by CRISPR/Cas9-mediated gene ablation.
Nakanishi T, Yamazaki M, Tachikawa K, Ueta A, Kawai M, Ozono K, Michigami T
Bone 2024 Apr;181:117044
Bone 2024 Apr;181:117044
Improving osseointegration and antimicrobial properties of titanium implants with black phosphorus nanosheets-hydroxyapatite composite coatings for vascularized bone regeneration.
Ma S, Sun R, Wang Y, Wei Y, Xu H, Liu X, Liang Z, Zhao L, Hu Y, Lian X, Guo M, Huang D
Journal of biomedical materials research. Part B, Applied biomaterials 2024 Apr;112(4):e35403
Journal of biomedical materials research. Part B, Applied biomaterials 2024 Apr;112(4):e35403
Suramin inhibits phenotypic transformation of vascular smooth muscle cells and neointima hyperplasia by suppressing transforming growth factor beta receptor 1 /Smad2/3 pathway activation.
Xu Y, Ge L, Rui Y, Wang Y, Wang Z, Yang J, Shi Y, Dong Z, Zhang Y, Zhang R, Yang T, Lv L, Xiang F, Chen S, Song A, Li T, Liu M, Guo Y
European journal of pharmacology 2024 Apr 5;968:176422
European journal of pharmacology 2024 Apr 5;968:176422
Single-Cell Transcriptional Profile Construction of Rat Pituitary Glands before and after Sexual Maturation and Identification of Novel Marker Spp1 in Gonadotropes.
Huang QH, Zhao GK, Wang HQ, Wei FH, Zhang JY, Zhang JB, Gao F, Yuan B
International journal of molecular sciences 2024 Apr 25;25(9)
International journal of molecular sciences 2024 Apr 25;25(9)
Trimethylamine N-oxide Promotes Atherosclerosis by Regulating Low-Density Lipoprotein-Induced Autophagy in Vascular Smooth Muscle Cells Through PI3K/AKT/mTOR Pathway.
Shi G, Zeng L, Shi J, Chen Y
International heart journal 2023;64(3):462-469
International heart journal 2023;64(3):462-469
miR-145 Alleviates Smooth Muscle Cell Phenotype Transition via ADAM17-Mediated ACE2 Shedding.
Wen J, Tang B, Guo L, Chen W, Tang X
International journal of hypertension 2023;2023:9497716
International journal of hypertension 2023;2023:9497716
Protective Effect of Alkaline Mineral Water on Calcium Oxalate-Induced Kidney Injury in Mice.
Liu L, Lin C, Li X, Cheng Y, Wang R, Luo C, Zhao X, Jiang Z
Evidence-based complementary and alternative medicine : eCAM 2023;2023:4559802
Evidence-based complementary and alternative medicine : eCAM 2023;2023:4559802
Therapeutic Effects of Mechanical Stress-Induced C2C12-Derived Exosomes on Glucocorticoid-Induced Osteoporosis Through miR-92a-3p/PTEN/AKT Signaling Pathway.
Xu N, Cui G, Zhao S, Li Y, Liu Q, Liu X, Zhao C, Feng R, Kuang M, Han S
International journal of nanomedicine 2023;18:7583-7603
International journal of nanomedicine 2023;18:7583-7603
High-fat diet causes undesirable bone regeneration by altering the bone marrow environment in rats.
Cai F, Yusufu A, Liu K, Chen W, Zhao R, Liu Y, Liu Y
Frontiers in endocrinology 2023;14:1088508
Frontiers in endocrinology 2023;14:1088508
Ectomesenchymal Six1 controls mandibular skeleton formation.
Luo S, Liu Z, Bian Q, Wang X
Frontiers in genetics 2023;14:1082911
Frontiers in genetics 2023;14:1082911
S-propargyl-cysteine promotes the stability of atherosclerotic plaque via maintaining vascular muscle contractile phenotype.
Ping L, Zhi-Ming L, Bi-Shan Z, Lei Z, Bo Y, Yi-Chun Z, Ming-Jie W
Frontiers in cell and developmental biology 2023;11:1291170
Frontiers in cell and developmental biology 2023;11:1291170
Sustained delivery of osteogenic growth peptide through injectable photoinitiated composite hydrogel for osteogenesis.
Liu B, Wu J, Sun X, Meng Q, Zhang J
Frontiers in bioengineering and biotechnology 2023;11:1228250
Frontiers in bioengineering and biotechnology 2023;11:1228250
Mir-142-5p inhibits the osteogenic differentiation of bone marrow mesenchymal stem cells by targeting Lhx8.
Du Y, Zhong H, Yu C, Lv Y, Yao Y, Peng Z, Lu S
Heliyon 2023 Sep;9(9):e19878
Heliyon 2023 Sep;9(9):e19878
The response and resistance to drugs in ovarian cancer cell lines in 2D monolayers and 3D spheroids.
Świerczewska M, Sterzyńska K, Ruciński M, Andrzejewska M, Nowicki M, Januchowski R
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115152
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115152
Effect of sulfonation time on physicochemical, osteogenic, antibacterial properties and biocompatibility of carbon fiber reinforced polyether ether ketone.
Su J, Wu Q, Xing X, Li D, Ou Y, He K, Lin H, Qiu Y, Rausch-Fan X, Chen J
Journal of the mechanical behavior of biomedical materials 2023 Sep;145:105979
Journal of the mechanical behavior of biomedical materials 2023 Sep;145:105979
Milk-Derived Small Extracellular Vesicles Promote Osteogenic Differentiation and Inhibit Inflammation via microRNA-21.
Liu R, Liu S, Wu S, Xia M, Liu W, Wang L, Dong M, Niu W
International journal of molecular sciences 2023 Sep 8;24(18)
International journal of molecular sciences 2023 Sep 8;24(18)
Single-cell epigenome analysis identifies molecular events controlling direct conversion of human fibroblasts to pancreatic ductal-like cells.
Fei L, Zhang K, Poddar N, Hautaniemi S, Sahu B
Developmental cell 2023 Sep 25;58(18):1701-1715.e8
Developmental cell 2023 Sep 25;58(18):1701-1715.e8
A composite membrane with microtopographical morphology to regulate cellular behavior for improved tissue regeneration.
Zhang R, Gong Y, Cai Z, Deng Y, Shi X, Pan H, Xu L, Zhang H
Acta biomaterialia 2023 Sep 15;168:125-143
Acta biomaterialia 2023 Sep 15;168:125-143
Inhibition of AT1R/IP3/IP3R-mediated Ca(2+) release protects against calcium oxalate crystals-induced renal oxidative stress.
Hong SY, Yang YY, Wang SG, Qin BL
Chemico-biological interactions 2023 Sep 1;382:110636
Chemico-biological interactions 2023 Sep 1;382:110636
A nano-conductive osteogenic hydrogel to locally promote calcium influx for electro-inspired bone defect regeneration.
Yu C, Ying X, Shahbazi MA, Yang L, Ma Z, Ye L, Yang W, Sun R, Gu T, Tang R, Fan S, Yao S
Biomaterials 2023 Oct;301:122266
Biomaterials 2023 Oct;301:122266
lncRNA MEG3 Promotes Osteogenic Differentiation of Tendon Stem Cells Via the miR-129-5p/TCF4/β-Catenin Axis and thus Contributes to Trauma-Induced Heterotopic Ossification.
Liu H, Sun Z, Luo G, Hu Y, Ruan H, Tu B, Li J, Fan C
Stem cell reviews and reports 2023 Oct;19(7):2311-2328
Stem cell reviews and reports 2023 Oct;19(7):2311-2328
Ganoderma lucidum polysaccharide peptide (GLPP) attenuates rheumatic arthritis in rats through inactivating NF-κB and MAPK signaling pathways.
Meng M, Wang L, Yao Y, Lin D, Wang C, Yao J, Sun H, Liu M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155010
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155010
Sodium-glucose cotransporter 2 inhibitor canagliflozin alleviates vascular calcification through suppression of nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing-3 inflammasome.
Chen A, Lan Z, Li L, Xie L, Liu X, Yang X, Wang S, Liang Q, Dong Q, Feng L, Li Y, Ye Y, Fu M, Lu L, Yan J
Cardiovascular research 2023 Oct 24;119(13):2368-2381
Cardiovascular research 2023 Oct 24;119(13):2368-2381
The Wnt/β-catenin signaling pathway inhibits osteoporosis by regulating the expression of TERT: an in vivo and in vitro study.
Cai Y, Sun H, Song X, Zhao J, Xu D, Liu M
Aging 2023 Oct 19;15(20):11471-11488
Aging 2023 Oct 19;15(20):11471-11488
Knockdown of Bach1 protects periodontal bone regeneration from inflammatory damage.
Yuan Z, Li J, Zou X, Liu C, Lu J, Ni C, Tang L, Wu X, Yan F
Journal of cellular and molecular medicine 2023 Nov;27(22):3465-3477
Journal of cellular and molecular medicine 2023 Nov;27(22):3465-3477
Impaired Growth Plate Maturation in XLH Is due to Both Excess FGF23 and Decreased 1,25-Dihydroxyvitamin D Signaling.
Yadav PS, Kobelski MM, Martins JS, Tao T, Liu ES, Demay MB
Endocrinology 2023 Nov 20;165(1)
Endocrinology 2023 Nov 20;165(1)
Melatonin-Primed Mesenchymal Stem Cells-Derived Small Extracellular Vesicles Alleviated Neurogenic Erectile Dysfunction by Reversing Phenotypic Modulation.
Chen Z, Zhai J, Ma J, Chen P, Lin W, Zhang W, Xiong J, Zhang C, Wei H
Advanced healthcare materials 2023 May;12(12):e2203087
Advanced healthcare materials 2023 May;12(12):e2203087
Apatinib remodels the immunosuppressive tumor ecosystem of gastric cancer enhancing anti-PD-1 immunotherapy.
Luo Q, Dong Z, Xie W, Fu X, Lin L, Zeng Q, Chen Y, Ye G, Chen M, Hu H, Wang L, Xie Y, Cai W
Cell reports 2023 May 30;42(5):112437
Cell reports 2023 May 30;42(5):112437
Apolipoprotein E facilitates titanium implant osseointegration by regulating osteogenesis-lipogenesis balance.
Wang YN, Yu L, Wang T, Liu S
International journal of biological macromolecules 2023 May 1;236:123998
International journal of biological macromolecules 2023 May 1;236:123998
Realizing Highly Efficient Sonodynamic Bactericidal Capability through the Phonon-Electron Coupling Effect Using Two-Dimensional Catalytic Planar Defects.
Mao C, Jin W, Xiang Y, Zhu Y, Wu J, Liu X, Wu S, Zheng Y, Cheung KMC, Yeung KWK
Advanced materials (Deerfield Beach, Fla.) 2023 Mar;35(9):e2208681
Advanced materials (Deerfield Beach, Fla.) 2023 Mar;35(9):e2208681
Mechanistic Insights into the Role of OPN in Mediating Brain Damage via Triggering Lysosomal Damage in Microglia/Macrophage.
Gai C, Zhao Y, Xin D, Li T, Cheng Y, Jiang Z, Song Y, Liu D, Wang Z
Cells 2023 Mar 9;12(6)
Cells 2023 Mar 9;12(6)
Bioinspired Piezoelectric Periosteum to Augment Bone Regeneration via Synergistic Immunomodulation and Osteogenesis.
Liu H, Shi Y, Zhu Y, Wu P, Deng Z, Dong Q, Wu M, Cai L
ACS applied materials & interfaces 2023 Mar 8;15(9):12273-12293
ACS applied materials & interfaces 2023 Mar 8;15(9):12273-12293
IL-1β contributes to the secretion of sclerostin by osteocytes and targeting sclerostin promotes spinal fusion at early stages.
Jiang Z, Jin L, Jiang C, Yan Z, Cao Y
Journal of orthopaedic surgery and research 2023 Mar 3;18(1):162
Journal of orthopaedic surgery and research 2023 Mar 3;18(1):162
FAM3A mediates the phenotypic switch of human aortic smooth muscle cells stimulated with oxidised low-density lipoprotein by influencing the PI3K-AKT pathway.
Yang L, Du B, Zhang S, Wang M
In vitro cellular & developmental biology. Animal 2023 Jun;59(6):431-442
In vitro cellular & developmental biology. Animal 2023 Jun;59(6):431-442
Bone microenvironment regulative hydrogels with ROS scavenging and prolonged oxygen-generating for enhancing bone repair.
Sun H, Xu J, Wang Y, Shen S, Xu X, Zhang L, Jiang Q
Bioactive materials 2023 Jun;24:477-496
Bioactive materials 2023 Jun;24:477-496
Continuously released Zn(2+) in 3D-printed PLGA/β-TCP/Zn scaffolds for bone defect repair by improving osteoinductive and anti-inflammatory properties.
Li C, Sun F, Tian J, Li J, Sun H, Zhang Y, Guo S, Lin Y, Sun X, Zhao Y
Bioactive materials 2023 Jun;24:361-375
Bioactive materials 2023 Jun;24:361-375
The marriage of immunomodulatory, angiogenic, and osteogenic capabilities in a piezoelectric hydrogel tissue engineering scaffold for military medicine.
Wu P, Shen L, Liu HF, Zou XH, Zhao J, Huang Y, Zhu YF, Li ZY, Xu C, Luo LH, Luo ZQ, Wu MH, Cai L, Li XK, Wang ZG
Military Medical Research 2023 Jul 31;10(1):35
Military Medical Research 2023 Jul 31;10(1):35
Clock genes are expressed in cementum and regulate the proliferation and mineralization of cementoblasts.
Liu G, Sun Q, Wu X, Liu Y, Chen Y, Cao Z, Hu Y, Xia H
In vitro cellular & developmental biology. Animal 2023 Jan;59(1):76-84
In vitro cellular & developmental biology. Animal 2023 Jan;59(1):76-84
Circular RNA CircSLC8A1 contributes to osteogenic differentiation in hBMSCs via CircSLC8A1/miR-144-3p/RUNX1 in periprosthetic osteolysis.
Yang B, Qin Y, Zhang A, Wang P, Jiang H, Shi Y, You G, Shen D, Ni S, Guo L, Liu Y
Journal of cellular and molecular medicine 2023 Jan;27(2):189-203
Journal of cellular and molecular medicine 2023 Jan;27(2):189-203
Single-cell RNA sequencing analysis revealed cellular and molecular immune profiles in lung squamous cell carcinoma.
Hao B, Zhang Z, Lu Z, Xiong J, Fan T, Song C, He R, Zhang L, Pan S, Li D, Meng H, Lin W, Luo B, Yang J, Li N, Geng Q
Translational oncology 2023 Jan;27:101568
Translational oncology 2023 Jan;27:101568
A TEMPOL and rapamycin loaded nanofiber-covered stent favors endothelialization and mitigates neointimal hyperplasia and local inflammation.
Wang R, Lu J, Yin J, Chen H, Liu H, Xu F, Zang T, Xu R, Li C, Wu Y, Wu Q, Fei X, Zhu M, Shen L, Ge J
Bioactive materials 2023 Jan;19:666-677
Bioactive materials 2023 Jan;19:666-677
Reversing the imbalance in bone homeostasis via sustained release of SIRT-1 agonist to promote bone healing under osteoporotic condition.
Zhang W, Zhou X, Hou W, Chen E, Ye C, Chen M, Lu Q, Yu X, Li W
Bioactive materials 2023 Jan;19:429-443
Bioactive materials 2023 Jan;19:429-443
Calcium Phosphate Bone Cements Incorporated with Black Phosphorus Nanosheets Enhanced Osteogenesis.
Ma S, Wei Y, Sun R, Xu H, Liu X, Wang Y, Liang Z, Hu Y, Lian X, Ma X, Huang D
ACS biomaterials science & engineering 2023 Jan 9;9(1):292-302
ACS biomaterials science & engineering 2023 Jan 9;9(1):292-302
Cannabidiol Rescues TNF-α-Inhibited Proliferation, Migration, and Osteogenic/Odontogenic Differentiation of Dental Pulp Stem Cells.
Yu L, Zeng L, Zhang Z, Zhu G, Xu Z, Xia J, Weng J, Li J, Pathak JL
Biomolecules 2023 Jan 6;13(1)
Biomolecules 2023 Jan 6;13(1)
PKR deficiency delays vascular aging via inhibiting GSDMD-mediated endothelial cell hyperactivation.
Peng Z, Tan X, Xie L, Li Z, Zhou S, Li Y
iScience 2023 Jan 20;26(1):105909
iScience 2023 Jan 20;26(1):105909
Bta-miR-200b promotes endometrial epithelial cell apoptosis by targeting MYB in cattle.
Lyu S, Zhai Y, Zhu X, Shi Q, Chen F, Zhang G, Zhang Z, Wang E
Theriogenology 2023 Jan 1;195:77-84
Theriogenology 2023 Jan 1;195:77-84
Type 1 diabetes mellitus leads to gingivitis and an early compensatory increase in bone remodeling.
Yuan X, Amin V, Zhu T, Kittaka M, Ueki Y, Bellido TM, Turkkahraman H
Journal of periodontology 2023 Feb;94(2):277-289
Journal of periodontology 2023 Feb;94(2):277-289
Metformin enhances the osteogenic activity of rat bone marrow mesenchymal stem cells by inhibiting oxidative stress induced by diabetes mellitus: an in vitro and in vivo study.
Dong K, Zhou WJ, Liu ZH
Journal of periodontal & implant science 2023 Feb;53(1):54-68
Journal of periodontal & implant science 2023 Feb;53(1):54-68
Ferroptotic stress facilitates smooth muscle cell dedifferentiation in arterial remodelling by disrupting mitochondrial homeostasis.
Ji QX, Zeng FY, Zhou J, Wu WB, Wang XJ, Zhang Z, Zhang GY, Tong J, Sun DY, Zhang JB, Cao WX, Shen FM, Lu JJ, Li DJ, Wang P
Cell death and differentiation 2023 Feb;30(2):457-474
Cell death and differentiation 2023 Feb;30(2):457-474
Macrophage migration inhibitory factor (MIF) inhibitor iSO-1 promotes staphylococcal protein A-induced osteogenic differentiation by inhibiting NF-κB signaling pathway.
Shi X, Wu Y, Ni H, Li M, Qi B, Xu Y
International immunopharmacology 2023 Feb;115:109600
International immunopharmacology 2023 Feb;115:109600
Stimulus-Responsive Zwitterionic Prodrug Delivery System with Sustained Release of Hydrogen Sulfide for Protective Aortic Dissection.
Ren B, Liu R, He Q, Wu T, Song L, Wang H, Gu J
ACS applied materials & interfaces 2023 Feb 9;
ACS applied materials & interfaces 2023 Feb 9;
Influence of FOSL1 Inhibition on Vascular Calcification and ROS Generation through Ferroptosis via P53-SLC7A11 Axis.
Shao S, Liu Y, Hong W, Mo Y, Shu F, Jiang L, Tan N
Biomedicines 2023 Feb 20;11(2)
Biomedicines 2023 Feb 20;11(2)
Retrospective identification of intrinsic factors that mark pluripotency potential in rare somatic cells.
Jain N, Goyal Y, Dunagin MC, Cote CJ, Mellis IA, Emert B, Jiang CL, Dardani IP, Reffsin S, Raj A
bioRxiv : the preprint server for biology 2023 Feb 10;
bioRxiv : the preprint server for biology 2023 Feb 10;
Hypoxia Inhibits Cell Cycle Progression and Cell Proliferation in Brain Microvascular Endothelial Cells via the miR-212-3p/MCM2 Axis.
Shi Q, Li S, Lyu Q, Zhang S, Bai Y, Ma J
International journal of molecular sciences 2023 Feb 1;24(3)
International journal of molecular sciences 2023 Feb 1;24(3)
Co-overexpression of OPN, IGF-1 and CNTF augment the therapeutic effect of DPSC on spinal cord injury.
Tao N, Dong X, Liu C, Lv L, Hu F, Zhang H, Li X, Geng P, Duan H, Wu CT, Wang H
Regenerative therapy 2023 Dec;24:651-661
Regenerative therapy 2023 Dec;24:651-661
Engineered muscle from micro-channeled PEG scaffold with magnetic Fe(3)O(4) fixation towards accelerating esophageal muscle repair.
Luo Y, Chen Y, Gu Z, Ni R, Feng P, Hu Z, Song L, Shen X, Gu C, Li J, Du T, Yang L, Zhang H, Zhu Y
Materials today. Bio 2023 Dec;23:100853
Materials today. Bio 2023 Dec;23:100853
Overexpression of LOX-1 in hepatocytes protects vascular smooth muscle cells from phenotype transformation and wire injury induced carotid neoatherosclerosis through ALOX15.
Zhang Q, Du G, Tong L, Guo X, Wei Y
Biochimica et biophysica acta. Molecular basis of disease 2023 Dec;1869(8):166805
Biochimica et biophysica acta. Molecular basis of disease 2023 Dec;1869(8):166805
CDN1163 alleviates SERCA2 dysfunction-induced pulmonary vascular remodeling by inhibiting the phenotypic transition of pulmonary artery smooth muscle cells.
Yu W, Zhang Q, Qiu Y, Chen H, Huang X, Xiao L, Xu G, Li S, Hu P, Tong X
Clinical and experimental hypertension (New York, N.Y. : 1993) 2023 Dec 31;45(1):2272062
Clinical and experimental hypertension (New York, N.Y. : 1993) 2023 Dec 31;45(1):2272062
Non-canonical function of histone methyltransferase G9a in the translational regulation of chronic inflammation.
Muneer A, Wang L, Xie L, Zhang F, Wu B, Mei L, Lenarcic EM, Feng EH, Song J, Xiong Y, Yu X, Wang C, Jain K, Strahl BD, Cook JG, Wan YY, Moorman NJ, Song H, Jin J, Chen X
Cell chemical biology 2023 Dec 21;30(12):1525-1541.e7
Cell chemical biology 2023 Dec 21;30(12):1525-1541.e7
The LRP5 high-bone-mass mutation causes alveolar bone accrual with minor craniofacial alteration.
Turkkahraman H, Flanagan S, Zhu T, Bellido TM, Yuan X
Journal of periodontal research 2023 Aug;58(4):723-732
Journal of periodontal research 2023 Aug;58(4):723-732
Transcription factor 21 accelerates vascular calcification in mice by activating the IL-6/STAT3 signaling pathway and the interplay between VSMCs and ECs.
Zhao XK, Zhu MM, Wang SN, Zhang TT, Wei XN, Wang CY, Zheng J, Zhu WY, Jiang MX, Xu SW, Yang XX, Duan YJ, Zhang BC, Han JH, Miao QR, Hu H, Chen YL
Acta pharmacologica Sinica 2023 Aug;44(8):1625-1636
Acta pharmacologica Sinica 2023 Aug;44(8):1625-1636
A Recombinant Parathyroid Hormone-Related Peptide Locally Applied in Osteoporotic Bone Defect.
Wang Y, Hu Y, Lan S, Chen Z, Zhang Y, Guo X, Cai L, Li J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Aug;10(22):e2300516
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Aug;10(22):e2300516
miR-342-5p promotes vascular smooth muscle cell phenotypic transition through a negative-feedback regulation of Notch signaling via targeting FOXO3.
Wen T, Duan Y, Gao D, Zhang X, Zhang X, Liang L, Yang Z, Zhang P, Zhang J, Sun J, Feng Y, Zheng Q, Han H, Yan X
Life sciences 2023 Aug 1;326:121828
Life sciences 2023 Aug 1;326:121828
Changes in N6-methyladenosine RNA methylomes of human periodontal ligament cells in response to inflammatory conditions.
Zou X, Liu C, Wu X, Yuan Z, Yan F
Journal of periodontal research 2023 Apr;58(2):444-455
Journal of periodontal research 2023 Apr;58(2):444-455
Nitration of cAMP-Response Element Binding Protein Participates in Myocardial Infarction-Induced Myocardial Fibrosis via Accelerating Transcription of Col1a2 and Cxcl12.
Xue K, Chen S, Chai J, Yan W, Zhu X, Ji D, Wu Y, Liu H, Wang W
Antioxidants & redox signaling 2023 Apr;38(10-12):709-730
Antioxidants & redox signaling 2023 Apr;38(10-12):709-730
Identification of hub genes and pathways in lung metastatic colorectal cancer.
Dai W, Guo C, Wang Y, Li Y, Xie R, Wu J, Yao B, Xie D, He L, Li Y, Huang H, Wang Y, Liu S
BMC cancer 2023 Apr 6;23(1):323
BMC cancer 2023 Apr 6;23(1):323
EMT-activated secretory and endocytic vesicular trafficking programs underlie a vulnerability to PI4K2A antagonism in lung cancer.
Tan X, Xiao GY, Wang S, Shi L, Zhao Y, Liu X, Yu J, Russell WK, Creighton CJ, Kurie JM
The Journal of clinical investigation 2023 Apr 3;133(7)
The Journal of clinical investigation 2023 Apr 3;133(7)
Osteopontin Promotes Macrophage M1 Polarization by Activation of the JAK1/STAT1/HMGB1 Signaling Pathway in Nonalcoholic Fatty Liver Disease.
Xu Z, Xi F, Deng X, Ni Y, Pu C, Wang D, Lou W, Zeng X, Su N, Chen C, Zeng Z, Deng L, Jiang M
Journal of clinical and translational hepatology 2023 Apr 28;11(2):273-283
Journal of clinical and translational hepatology 2023 Apr 28;11(2):273-283
Synergistic Effect of Magneto-Mechanical Bioengineered Stem Cells and Magnetic Field to Alleviate Osteoporosis.
Yu C, Yang W, Yang L, Ye L, Sun R, Gu T, Ying X, Wang M, Tang R, Fan S, Yao S
ACS applied materials & interfaces 2023 Apr 26;15(16):19976-19988
ACS applied materials & interfaces 2023 Apr 26;15(16):19976-19988
BRG1 is involved in vascular calcification in chronic renal disease via autophagy of vascular smooth muscle cells.
Feng Y, Yu M, Wang C, Xia J, Huang L, Tang Y, Xiao Q, Pu L, Wang L, Li G, Li Y
iScience 2023 Apr 21;26(4):106485
iScience 2023 Apr 21;26(4):106485
Potential of an Aligned Porous Hydrogel Scaffold Combined with Periodontal Ligament Stem Cells or Gingival Mesenchymal Stem Cells to Promote Tissue Regeneration in Rat Periodontal Defects.
Wang W, Wang A, Hu G, Bian M, Chen L, Zhao Q, Sun W, Wu Y
ACS biomaterials science & engineering 2023 Apr 10;9(4):1961-1975
ACS biomaterials science & engineering 2023 Apr 10;9(4):1961-1975
Biophysical Analysis and Preclinical Pharmacokinetics-Pharmacodynamics of Tangential Flow Filtration Fractionated Polymerized Human Hemoglobin as a Red Blood Cell Substitute.
Greenfield A, Lamb DR, Gu X, Thangaraju K, Setua S, Yahya A, Vahedi A, Khan MA, Wang Q, Buehler PW, Palmer AF
Biomacromolecules 2023 Apr 10;24(4):1855-1870
Biomacromolecules 2023 Apr 10;24(4):1855-1870
Hsa_circRNA_0008028 Deficiency Ameliorates High Glucose-Induced Proliferation, Calcification, and Autophagy of Vascular Smooth Muscle Cells via miR-182-5p/TRIB3 Axis.
Shi L, Li Y, Shi M, Li X, Li G, Cen J, Liu D, Wei C, Lin Y
Oxidative medicine and cellular longevity 2022;2022:5142381
Oxidative medicine and cellular longevity 2022;2022:5142381
Preparation and Biocompatibility of Core-Shell Microspheres for Sequential, Sustained Release of BMP-2 and VEGF.
Liu Z, Xu Z, Wang X, Zhang Y, Wu Y, Jiang D, Jia R
BioMed research international 2022;2022:4072975
BioMed research international 2022;2022:4072975
OPN Promotes Cell Proliferation and Invasion through NF-κB in Human Esophageal Squamous Cell Carcinoma.
Chen B, Liang S, Guo H, Xu L, Li J, Peng J
Genetics research 2022;2022:3154827
Genetics research 2022;2022:3154827
Assessing serum levels of SM22α as a new biomarker for patients with aortic aneurysm/dissection.
Zhang N, Wang YY, Hu HJ, Lu G, Xu X, Dou YQ, Cui W, Gao SJ, Han M
PloS one 2022;17(3):e0264942
PloS one 2022;17(3):e0264942
Akkermansia muciniphila Alters Gut Microbiota and Immune System to Improve Cardiovascular Diseases in Murine Model.
He X, Bai Y, Zhou H, Wu K
Frontiers in microbiology 2022;13:906920
Frontiers in microbiology 2022;13:906920
Pan-Cancer Analysis of the Immunological Role of PDIA5: A Potential Target for Immunotherapy.
Chen Y, He J, Chen R, Wang Z, Dai Z, Liang X, Wu W, Luo P, Zhang J, Peng Y, Zhang N, Liu Z, Zhang L, Zhang H, Cheng Q
Frontiers in immunology 2022;13:881722
Frontiers in immunology 2022;13:881722
Hypoxia During the Consolidation Phase of Distraction Osteogenesis Promotes Bone Regeneration.
Liu Y, Liu J, Cai F, Liu K, Zhang X, Yusufu A
Frontiers in physiology 2022;13:804469
Frontiers in physiology 2022;13:804469
Pan-Cancer Analysis Reveals a Distinct Neutrophil Extracellular Trap-Associated Regulatory Pattern.
Shen XT, Xie SZ, Xu J, Yang LY, Qin LX
Frontiers in immunology 2022;13:798022
Frontiers in immunology 2022;13:798022
CCAAT/Enhancer-Binding Protein Alpha Is a Novel Regulator of Vascular Smooth Muscle Cell Osteochondrogenic Transition and Vascular Calcification.
Chen P, Hong W, Chen Z, Gordillo-Martinez F, Wang S, Fan H, Liu Y, Dai Y, Wang B, Jiang L, Yu H, He P
Frontiers in physiology 2022;13:755371
Frontiers in physiology 2022;13:755371
TSH-SPP1/TRβ-TSH positive feedback loop mediates fat deposition of hepatocyte: Crosstalk between thyroid and liver.
Huang B, Wen W, Ye S
Frontiers in immunology 2022;13:1009912
Frontiers in immunology 2022;13:1009912
Dissecting a hypoxia-related angiogenic gene signature for predicting prognosis and immune status in hepatocellular carcinoma.
Zhang G, Xiao Y, Zhang X, Fan W, Zhao Y, Wu Y, Wang H, Li J
Frontiers in oncology 2022;12:978050
Frontiers in oncology 2022;12:978050
Potassium Titanate Assembled Titanium Dioxide Nanotube Arrays Endow Titanium Implants Excellent Osseointegration Performance and Nerve Formation Potential.
Zhao H, Liu F, Yin Y, Wang S
Frontiers in chemistry 2022;10:839093
Frontiers in chemistry 2022;10:839093
Construction and osteogenic effects of 3D-printed porous titanium alloy loaded with VEGF/BMP-2 shell-core microspheres in a sustained-release system.
Liu Z, Xu Z, Wang X, Zhang Y, Wu Y, Jiang D, Jia R
Frontiers in bioengineering and biotechnology 2022;10:1028278
Frontiers in bioengineering and biotechnology 2022;10:1028278
NRF2 is a critical regulator and therapeutic target of metal implant particle-incurred bone damage.
Dong J, Zhang L, Ruan B, Lv Z, Wang H, Wang Y, Jiang Q, Cao W
Biomaterials 2022 Sep;288:121742
Biomaterials 2022 Sep;288:121742
Negative pressure wound therapy improves bone regeneration by promoting osteogenic differentiation via the AMPK-ULK1-autophagy axis.
Zhang S, Xie Y, Yan F, Zhang Y, Yang Z, Chen Z, Zhao Y, Huang Z, Cai L, Deng Z
Autophagy 2022 Sep;18(9):2229-2245
Autophagy 2022 Sep;18(9):2229-2245
Dual Biosignal-Functional Injectable Microspheres for Remodeling Osteogenic Microenvironment.
Sun Y, Zhou Q, Du Y, Sun J, Bi W, Liu W, Li R, Wu X, Yang F, Song L, Li N, Cui W, Yu Y
Small (Weinheim an der Bergstrasse, Germany) 2022 Sep;18(36):e2201656
Small (Weinheim an der Bergstrasse, Germany) 2022 Sep;18(36):e2201656
Substitution of SERCA2 Cys(674) accelerates aortic aneurysm by inducing endoplasmic reticulum stress and promoting cell apoptosis.
Wang L, Yang Z, Wang S, Que Y, Shu X, Wu F, Liu G, Li S, Hu P, Chen H, Shi J, Tong X
British journal of pharmacology 2022 Sep;179(17):4423-4439
British journal of pharmacology 2022 Sep;179(17):4423-4439
The Protective Effects on Ischemia-Reperfusion Injury Mechanisms of the Thoracic Aorta in Daurian Ground Squirrels (Spermophilus dauricus) over the Torpor-Arousal Cycle of Hibernation.
Han Y, Miao W, Hao Z, An N, Yang Y, Zhang Z, Chen J, Storey KB, Lefai E, Chang H
International journal of molecular sciences 2022 Sep 6;23(18)
International journal of molecular sciences 2022 Sep 6;23(18)
Oxalate induces the ossification of RTECs by activating the JAK2/STAT3 signaling pathway and participates in the formation of kidney stones.
Song Q, Liao W, He Z, Li D, Dong C, Song C, Yang S
Archives of biochemistry and biophysics 2022 Sep 30;727:109325
Archives of biochemistry and biophysics 2022 Sep 30;727:109325
Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Enhance the Osteoblastic Differentiation of Periodontal Ligament Stem Cells Under High Glucose Conditions Through the PI3K/AKT Signaling Pathway.
Yang S, Zhu B, Tian XY, Yu HY, Qiao B, Zhao LS, Zhang B
Biomedical and environmental sciences : BES 2022 Sep 20;35(9):811-820
Biomedical and environmental sciences : BES 2022 Sep 20;35(9):811-820
Impact of Resolvin D1 on the inflammatory phenotype of periodontal ligament cell response to hypoxia.
Cai J, Liu J, Yan J, Lu X, Wang X, Li S, Mustafa K, Wang H, Xue Y, Mustafa M, Kantarci A, Xing Z
Journal of periodontal research 2022 Oct;57(5):1034-1042
Journal of periodontal research 2022 Oct;57(5):1034-1042
LncRNA LINC00281/Annexin A2 Regulates Vascular Smooth Muscle Cell Phenotype Switching via the Nuclear Factor-Kappa B Signaling Pathway.
Cheng L, Wang H, Maboh R, Mao G, Wu X, Chen H
Journal of cardiovascular translational research 2022 Oct;15(5):971-984
Journal of cardiovascular translational research 2022 Oct;15(5):971-984
Gut microbiome dysbiosis contributes to abdominal aortic aneurysm by promoting neutrophil extracellular trap formation.
Tian Z, Zhang Y, Zheng Z, Zhang M, Zhang T, Jin J, Zhang X, Yao G, Kong D, Zhang C, Wang Z, Zhang Q
Cell host & microbe 2022 Oct 12;30(10):1450-1463.e8
Cell host & microbe 2022 Oct 12;30(10):1450-1463.e8
Iron overload-induced ferroptosis of osteoblasts inhibits osteogenesis and promotes osteoporosis: An in vitro and in vivo study.
Jiang Z, Wang H, Qi G, Jiang C, Chen K, Yan Z
IUBMB life 2022 Nov;74(11):1052-1069
IUBMB life 2022 Nov;74(11):1052-1069
Identification of osteopontin as a urinary biomarker for autosomal dominant polycystic kidney disease progression.
Kim H, Sung J, Bae JY, Lee P, Oh YK, Kim H
Kidney research and clinical practice 2022 Nov;41(6):730-740
Kidney research and clinical practice 2022 Nov;41(6):730-740
Fecal microbiota transplantation ameliorates bone loss in mice with ovariectomy-induced osteoporosis via modulating gut microbiota and metabolic function.
Zhang YW, Cao MM, Li YJ, Lu PP, Dai GC, Zhang M, Wang H, Rui YF
Journal of orthopaedic translation 2022 Nov;37:46-60
Journal of orthopaedic translation 2022 Nov;37:46-60
Niobium promotes fracture healing in rats by regulating the PI3K-Akt signalling pathway: An in vivo and in vitro study.
Tan J, Li J, Cao B, Wu J, Luo D, Ran Z, Deng L, Li X, Jiang W, Xie K, Wang L, Hao Y
Journal of orthopaedic translation 2022 Nov;37:113-125
Journal of orthopaedic translation 2022 Nov;37:113-125
MiR-145 inhibits the differentiation and proliferation of bone marrow stromal mesenchymal stem cells by GABARAPL1 in steroid-induced femoral head necrosis.
Xu P, Chang J, Ma G, Liao F, Xu T, Wu Y, Yin Z
BMC musculoskeletal disorders 2022 Nov 26;23(1):1020
BMC musculoskeletal disorders 2022 Nov 26;23(1):1020
CircZXDC Promotes Vascular Smooth Muscle Cell Transdifferentiation via Regulating miRNA-125a-3p/ABCC6 in Moyamoya Disease.
Liu Y, Huang Y, Zhang X, Ma X, He X, Gan C, Zou X, Wang S, Shu K, Lei T, Zhang H
Cells 2022 Nov 26;11(23)
Cells 2022 Nov 26;11(23)
Decorin Promotes Osteoblastic Differentiation of Human Periodontal Ligament Stem Cells.
Adachi O, Sugii H, Itoyama T, Fujino S, Kaneko H, Tomokiyo A, Hamano S, Hasegawa D, Obata J, Yoshida S, Kadowaki M, Sugiura R, Albougha MS, Maeda H
Molecules (Basel, Switzerland) 2022 Nov 25;27(23)
Molecules (Basel, Switzerland) 2022 Nov 25;27(23)
Salidroside protects against osteoporosis in ovariectomized rats by inhibiting oxidative stress and promoting osteogenesis via Nrf2 activation.
Wang YF, Chang YY, Zhang XM, Gao MT, Zhang QL, Li X, Zhang L, Yao WF
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:154020
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:154020
Carboxymethyl chitin or chitosan for osteoinduction effect on the human periodontal ligament stem cells.
Fan C, Li Z, Ji Q, Sun H, Liang Y, Yang P
Dental materials journal 2022 May 31;41(3):392-401
Dental materials journal 2022 May 31;41(3):392-401
Intraoperative Hypothermia Induces Vascular Dysfunction in the CA1 Region of Rat Hippocampus.
Li T, Xu G, Yi J, Huang Y
Brain sciences 2022 May 27;12(6)
Brain sciences 2022 May 27;12(6)
Mussel-inspired multifunctional surface through promoting osteogenesis and inhibiting osteoclastogenesis to facilitate bone regeneration.
Wu M, Zhang Y, Wu P, Chen F, Yang Z, Zhang S, Xiao L, Cai L, Zhang C, Chen Y, Deng Z
NPJ Regenerative medicine 2022 May 13;7(1):29
NPJ Regenerative medicine 2022 May 13;7(1):29
STARD3NL inhibits the osteogenic differentiation by inactivating the Wnt/β-catenin pathway via binding to Annexin A2 in osteoporosis.
Xu Y, Bao X, Chen X, Wu P, Chen S, Zhang B, Ma J, Xu G, Ma D
Journal of cellular and molecular medicine 2022 Mar;26(5):1643-1655
Journal of cellular and molecular medicine 2022 Mar;26(5):1643-1655
Molecular feature of arterial remodeling in the brain arteriovenous malformation revealed by arteriovenous shunt rat model and RNA sequencing.
Chen B, Tao W, Yan L, Zeng M, Song L, Huang Z, Chen F
International immunopharmacology 2022 Jun;107:108653
International immunopharmacology 2022 Jun;107:108653
MicroRNA-27a-3p inhibits lung and skin fibrosis of systemic sclerosis by negatively regulating SPP1.
Cheng Q, Chen M, Wang H, Chen X, Wu H, Du Y, Xue J
Genomics 2022 Jul;114(4):110391
Genomics 2022 Jul;114(4):110391
Iron deficiency exacerbates aortic medial degeneration by inducing excessive mitochondrial fission.
Zhong X, Wu Q, Wang Z, Zhang M, Zheng S, Shi F, Chen Y, Che Y, Yuan S, Xing K
Food & function 2022 Jul 18;13(14):7666-7683
Food & function 2022 Jul 18;13(14):7666-7683
Semaphorin3A promotes osseointegration of titanium implants in osteoporotic rabbits.
Song A, Jiang F, Wang Y, Wang M, Wu Y, Zheng Y, Song X, Zhang W, Zhou J
Clinical oral investigations 2022 Jan;26(1):969-979
Clinical oral investigations 2022 Jan;26(1):969-979
Increased expression of osteopontin in subchondral bone promotes bone turnover and remodeling, and accelerates the progression of OA in a mouse model.
Lin C, Chen Z, Guo D, Zhou L, Lin S, Li C, Li S, Wang X, Lin B, Ding Y
Aging 2022 Jan 4;14(1):253-271
Aging 2022 Jan 4;14(1):253-271
SIRT6 protects vascular smooth muscle cells from osteogenic transdifferentiation via Runx2 in chronic kidney disease.
Li W, Feng W, Su X, Luo D, Li Z, Zhou Y, Zhu Y, Zhang M, Chen J, Liu B, Huang H
The Journal of clinical investigation 2022 Jan 4;132(1)
The Journal of clinical investigation 2022 Jan 4;132(1)
Development of Intracorporeal Differentiation of Stem Cells to Induce One-Step Mastoid Bone Reconstruction during Otitis Media Surgeries.
Park SH, Kim H, Lee YY, Kim YJ, Jang JH, Choo OS, Choung YH
Polymers 2022 Feb 23;14(5)
Polymers 2022 Feb 23;14(5)
Osteopontin expression in the invasive front stroma of colorectal adenocarcinoma is associated with tumor budding and prognosis.
Nakajima T, Uehara T, Iwaya M, Matsuda K, Wada M, Nagaya T, Ehara T, Ota H
Pathology, research and practice 2022 Dec;240:154190
Pathology, research and practice 2022 Dec;240:154190
Dickkopf1 (Dkk1) Alleviates Vascular Calcification by Regulating the Degradation of Phospholipase D1 (PLD1).
Li X, Liu XL, Li X, Zhao YC, Wang QQ, Zhong HY, Liu DD, Yuan C, Zheng TF, Zhang M
Journal of cardiovascular translational research 2022 Dec;15(6):1327-1339
Journal of cardiovascular translational research 2022 Dec;15(6):1327-1339
Halide-containing bioactive glasses enhance osteogenesis in vitro and in vivo.
Chen X, Liu Y, Zhao Y, Ouyang Z, Zhou H, Li L, Li L, Li F, Xie X, Hill RG, Wang S, Chen X
Biomaterials advances 2022 Dec;143:213173
Biomaterials advances 2022 Dec;143:213173
PVT1/miR-145-5p/HK2 modulates vascular smooth muscle cells phenotype switch via glycolysis: The new perspective on the spiral artery remodeling.
Wu M, Liu W, Huang H, Chen Z, Chen Y, Zhong Y, Jin Z, Liu X, Zou L
Placenta 2022 Dec;130:25-33
Placenta 2022 Dec;130:25-33
Mesoporous Silica Promotes Osteogenesis of Human Adipose-Derived Stem Cells Identified by a High-Throughput Microfluidic Chip Assay.
Chen X, Wang C, Hao M, Zhao H, Xia H, Yu L, Li D, Qiu J, Li H, Han L, Sang Y
Pharmaceutics 2022 Dec 6;14(12)
Pharmaceutics 2022 Dec 6;14(12)
Electroactive Hydroxyapatite/Carbon Nanofiber Scaffolds for Osteogenic Differentiation of Human Adipose-Derived Stem Cells.
Sun B, Sun Y, Han S, Zhang R, Wang X, Meng C, Ji T, Sun C, Ren N, Ge S, Liu H, Yu Y, Wang J
International journal of molecular sciences 2022 Dec 28;24(1)
International journal of molecular sciences 2022 Dec 28;24(1)
Multi-Transcriptomic Analysis Reveals the Heterogeneity and Tumor-Promoting Role of SPP1/CD44-Mediated Intratumoral Crosstalk in Gastric Cancer.
Xie W, Cheng J, Hong Z, Cai W, Zhuo H, Hou J, Lin L, Wei X, Wang K, Chen X, Song Y, Wang Z, Cai J
Cancers 2022 Dec 27;15(1)
Cancers 2022 Dec 27;15(1)
Icariin Treatment Rescues Diabetes Induced Bone Loss via Scavenging ROS and Activating Primary Cilia/Gli2/Osteocalcin Signaling Pathway.
Liu J, Cheng Q, Wu X, Zhu H, Deng X, Wang M, Yang S, Xu J, Chen Q, Li M, Liu X, Wang C
Cells 2022 Dec 16;11(24)
Cells 2022 Dec 16;11(24)
Circular RNA BIRC6 depletion promotes osteogenic differentiation of periodontal ligament stem cells via the miR-543/PTEN/PI3K/AKT/mTOR signaling pathway in the inflammatory microenvironment.
Zhao X, Sun W, Guo B, Cui L
Stem cell research & therapy 2022 Aug 13;13(1):417
Stem cell research & therapy 2022 Aug 13;13(1):417
The Annexin A2-Notch regulatory loop in hepatocytes promotes liver fibrosis in NAFLD by increasing osteopontin expression.
Wang G, Duan J, Pu G, Ye C, Li Y, Xiu W, Xu J, Liu B, Zhu Y, Wang C
Biochimica et biophysica acta. Molecular basis of disease 2022 Aug 1;1868(8):166413
Biochimica et biophysica acta. Molecular basis of disease 2022 Aug 1;1868(8):166413
Cinnamaldehyde protects against ligature-induced periodontitis through the inhibition of microbial accumulation and inflammatory responses of host immune cells.
Ou Y, Yan M, Gao G, Wang W, Lu Q, Chen J
Food & function 2022 Aug 1;13(15):8091-8106
Food & function 2022 Aug 1;13(15):8091-8106
Immunohistochemical expression of osteopontin and collagens in choroid plexus of human brains.
Wakamatsu K, Chiba Y, Murakami R, Matsumoto K, Miyai Y, Kawauchi M, Yanase K, Uemura N, Ueno M
Neuropathology : official journal of the Japanese Society of Neuropathology 2022 Apr;42(2):117-125
Neuropathology : official journal of the Japanese Society of Neuropathology 2022 Apr;42(2):117-125
N-acetylcysteine promotes cyclic mechanical stress-induced osteogenic differentiation of periodontal ligament stem cells by down-regulating Nrf2 expression.
Xi X, Li ZX, Zhao Y, Liu H, Chen S, Liu DX
Journal of dental sciences 2022 Apr;17(2):750-762
Journal of dental sciences 2022 Apr;17(2):750-762
Bmal1 promotes cementoblast differentiation and cementum mineralization via Wnt/β-catenin signaling.
Liu S, Zhou Y, Chen Y, Liu Y, Peng S, Cao Z, Xia H
Acta histochemica 2022 Apr;124(3):151868
Acta histochemica 2022 Apr;124(3):151868
Decoding the temporal and regional specification of microglia in the developing human brain.
Li Y, Li Z, Yang M, Wang F, Zhang Y, Li R, Li Q, Gong Y, Wang B, Fan B, Wang C, Chen L, Li H, Ong J, Teng Z, Jin L, Wang YL, Du P, Jiao J
Cell stem cell 2022 Apr 7;29(4):620-634.e6
Cell stem cell 2022 Apr 7;29(4):620-634.e6
ELAV-like RNA binding protein 1 regulates osteogenesis in diabetic osteoporosis: Involvement of divalent metal transporter 1.
Ren Y, Yang M, Wang X, Xu B, Xu Z, Su B
Molecular and cellular endocrinology 2022 Apr 15;546:111559
Molecular and cellular endocrinology 2022 Apr 15;546:111559
Role of (pro)renin receptor in cyclosporin A-induced nephropathy.
Hu J, Tan Y, Chen Y, Mo S, Hekking B, Su J, Pu M, Lu A, Du Y, Symons JD, Yang T
American journal of physiology. Renal physiology 2022 Apr 1;322(4):F437-F448
American journal of physiology. Renal physiology 2022 Apr 1;322(4):F437-F448
Bioinformatics analysis of laryngeal squamous cell carcinoma: seeking key candidate genes and pathways.
Ma J, Hu X, Dai B, Wang Q, Wang H
PeerJ 2021;9:e11259
PeerJ 2021;9:e11259
Nrf2 Activation Is Involved in Cyclic Mechanical Stress-Stimulated Osteogenic Differentiation in Periodontal Ligament Stem Cells via PI3K/Akt Signaling and HO1-SOD2 Interaction.
Xi X, Li Z, Liu H, Chen S, Liu D
Frontiers in cell and developmental biology 2021;9:816000
Frontiers in cell and developmental biology 2021;9:816000
Cyclic Distraction-Compression Dynamization Technique Enhances the Bone Formation During Distraction Osteogenesis.
Liu Y, Cai F, Liu K, Liu J, Zhang X, Yusufu A
Frontiers in bioengineering and biotechnology 2021;9:810723
Frontiers in bioengineering and biotechnology 2021;9:810723
Long Non-coding RNAs LOC100126784 and POM121L9P Derived From Bone Marrow Mesenchymal Stem Cells Enhance Osteogenic Differentiation via the miR-503-5p/SORBS1 Axis.
Xu Y, Xin R, Sun H, Long D, Li Z, Liao H, Xue T, Zhang Z, Kang Y, Mao G
Frontiers in cell and developmental biology 2021;9:723759
Frontiers in cell and developmental biology 2021;9:723759
FBS-Derived Exosomes as a Natural Nano-Scale Carrier for Icariin Promote Osteoblast Proliferation.
Dong M, Wu S, Xu H, Yu X, Wang L, Bai H, Niu W
Frontiers in bioengineering and biotechnology 2021;9:615920
Frontiers in bioengineering and biotechnology 2021;9:615920
PRDX2 Protects Against Atherosclerosis by Regulating the Phenotype and Function of the Vascular Smooth Muscle Cell.
Li J, Wang C, Wang W, Liu L, Zhang Q, Zhang J, Wang B, Wang S, Hou L, Gao C, Yu X, Sun L
Frontiers in cardiovascular medicine 2021;8:624796
Frontiers in cardiovascular medicine 2021;8:624796
Metformin Inhibits Abdominal Aortic Aneurysm Formation through the Activation of the AMPK/mTOR Signaling Pathway.
He J, Li N, Fan Y, Zhao X, Liu C, Hu X
Journal of vascular research 2021;58(3):148-158
Journal of vascular research 2021;58(3):148-158
Quantitative Proteomics Reveals the Dynamic Pathophysiology Across Different Stages in a Rat Model of Severe Traumatic Brain Injury.
Luo W, Yang Z, Zhang W, Zhou D, Guo X, Wang S, He F, Wang Y
Frontiers in molecular neuroscience 2021;14:785938
Frontiers in molecular neuroscience 2021;14:785938
Dura cells in the etiopathogenesis of Crouzon syndrome: the effects of FGFR2 mutations in the dura cells on the proliferation of osteoblasts through the hippo/YAP mediated transcriptional regulation pathway.
Dong XH, Zhang MZ, Lai CZ, Li CC, Du L, Song GD, Zong XL, Jin XL
American journal of translational research 2021;13(10):11255-11270
American journal of translational research 2021;13(10):11255-11270
Identification and Validation of a Tumor Microenvironment-Related Gene Signature in Hepatocellular Carcinoma Prognosis.
Huang C, Zhang C, Sheng J, Wang D, Zhao Y, Qian L, Xie L, Meng Z
Frontiers in genetics 2021;12:717319
Frontiers in genetics 2021;12:717319
Identification of VWF as a Novel Biomarker in Lung Adenocarcinoma by Comprehensive Analysis.
He Y, Liu R, Yang M, Bi W, Zhou L, Zhang S, Jin J, Liang X, Zhang P
Frontiers in oncology 2021;11:639600
Frontiers in oncology 2021;11:639600
Exogenous H(2) S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
Zhang L, Jiang X, Liu N, Li M, Kang J, Chen L, Tang J, Dong S, Lu F, Zhang W
Journal of cellular and molecular medicine 2021 Sep;25(17):8201-8214
Journal of cellular and molecular medicine 2021 Sep;25(17):8201-8214
Biomimetic Cell-Substrate of Chitosan-Cross-linked Polyaniline Patterning on TiO(2) Nanotubes Enables hBM-MSCs to Differentiate the Osteoblast Cell Type.
Kandel R, Jang SR, Shrestha S, Lee SY, Shrestha BK, Park CH, Kim CS
ACS applied materials & interfaces 2021 Oct 6;13(39):47100-47117
ACS applied materials & interfaces 2021 Oct 6;13(39):47100-47117
Polydopamine-Coated Poly(l-lactide) Nanofibers with Controlled Release of VEGF and BMP-2 as a Regenerative Periosteum.
Sun H, Dong J, Wang Y, Shen S, Shi Y, Zhang L, Zhao J, Sun X, Jiang Q
ACS biomaterials science & engineering 2021 Oct 11;7(10):4883-4897
ACS biomaterials science & engineering 2021 Oct 11;7(10):4883-4897
Association of urinary ketamine and APOA1 levels with bladder dysfunction in ketamine abusers revealed via proteomics and targeted metabolite analyses.
Liu JC, Chen YT, Hsieh YJ, Wu CC, Huang MC, Hsu YC, Wu CT, Chen CK, Dash S, Yu JS
Scientific reports 2021 May 5;11(1):9583
Scientific reports 2021 May 5;11(1):9583
ET(A)R silencing ameliorated neurovascular injury after SAH in rats through ERK/KLF4-mediated phenotypic transformation of smooth muscle cells.
Zhang Z, Chen H, Liu L, Zhao G, He J, Liu H, Zhou C, Liu X, Sun X, Guo Z
Experimental neurology 2021 Mar;337:113596
Experimental neurology 2021 Mar;337:113596
Primary cilia regulate gastric cancer-induced bone loss via cilia/Wnt/β-catenin signaling pathway.
Xu J, Deng X, Wu X, Zhu H, Zhu Y, Liu J, Chen Q, Yuan C, Liu G, Wang C
Aging 2021 Mar 9;13(6):8989-9010
Aging 2021 Mar 9;13(6):8989-9010
Inactivation of SERCA2 Cys(674) accelerates aortic aneurysms by suppressing PPARγ.
Que Y, Shu X, Wang L, Wang S, Li S, Hu P, Tong X
British journal of pharmacology 2021 Jun;178(11):2305-2323
British journal of pharmacology 2021 Jun;178(11):2305-2323
Long-lasting renewable antibacterial porous polymeric coatings enable titanium biomaterials to prevent and treat peri-implant infection.
Wu S, Xu J, Zou L, Luo S, Yao R, Zheng B, Liang G, Wu D, Li Y
Nature communications 2021 Jun 3;12(1):3303
Nature communications 2021 Jun 3;12(1):3303
Nrf2 activation is involved in osteogenic differentiation of periodontal ligament stem cells under cyclic mechanical stretch.
Xi X, Zhao Y, Liu H, Li Z, Chen S, Liu D
Experimental cell research 2021 Jun 15;403(2):112598
Experimental cell research 2021 Jun 15;403(2):112598
The preventive and therapeutic effects of AAV1-KLF4-shRNA in cigarette smoke-induced pulmonary hypertension.
Sun D, Ding D, Li Q, Xie M, Xu Y, Liu X
Journal of cellular and molecular medicine 2021 Jan;25(2):1238-1251
Journal of cellular and molecular medicine 2021 Jan;25(2):1238-1251
A protumorigenic secretory pathway activated by p53 deficiency in lung adenocarcinoma.
Tan X, Shi L, Banerjee P, Liu X, Guo HF, Yu J, Bota-Rabassedas N, Rodriguez BL, Gibbons DL, Russell WK, Creighton CJ, Kurie JM
The Journal of clinical investigation 2021 Jan 4;131(1)
The Journal of clinical investigation 2021 Jan 4;131(1)
A Dual Role of Heme Oxygenase-1 in Angiotensin II-Induced Abdominal Aortic Aneurysm in the Normolipidemic Mice.
Kopacz A, Klóska D, Werner E, Hajduk K, Grochot-Przęczek A, Józkowicz A, Piechota-Polańczyk A
Cells 2021 Jan 15;10(1)
Cells 2021 Jan 15;10(1)
Significance of MR/OPN/HMGB1 axis in NAFLD-associated hepatic fibrogenesis.
Tang M, Jia H, Chen S, Yang B, Patpur BK, Song W, Chang Y, Li J, Yang C
Life sciences 2021 Jan 1;264:118619
Life sciences 2021 Jan 1;264:118619
lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.
Dai W, Wang M, Wang P, Wen J, Wang J, Cha S, Xiao X, He Y, Shu R, Bai D
International journal of molecular medicine 2021 Feb;47(2):607-620
International journal of molecular medicine 2021 Feb;47(2):607-620
Prostacyclin facilitates vascular smooth muscle cell phenotypic transformation via activating TP receptors when IP receptors are deficient.
Li Z, Luo W, Fang S, Chen X, Lin T, Zhou S, Zhang L, Yang W, Li Z, Ye J, Wang J, Liu P, Li Z
Acta physiologica (Oxford, England) 2021 Feb;231(2):e13555
Acta physiologica (Oxford, England) 2021 Feb;231(2):e13555
MSCs-extracellular vesicles attenuated neuroinflammation, synapse damage and microglial phagocytosis after hypoxia-ischemia injury by preventing osteopontin expression.
Xin D, Li T, Chu X, Ke H, Liu D, Wang Z
Pharmacological research 2021 Feb;164:105322
Pharmacological research 2021 Feb;164:105322
MicroRNA-520c-3p targeting of RelA/p65 suppresses atherosclerotic plaque formation.
Wang J, Hu X, Hu X, Gao F, Li M, Cui Y, Wei X, Qin Y, Zhang C, Zhao Y, Gao Y
The international journal of biochemistry & cell biology 2021 Feb;131:105873
The international journal of biochemistry & cell biology 2021 Feb;131:105873
Polypeptides IGF-1C and P24 synergistically promote osteogenic differentiation of bone marrow mesenchymal stem cells in vitro through the p38 and JNK signaling pathways.
Ran G, Fang W, Zhang L, Peng Y, Wu A, Li J, Ding X, Zeng S, He Y
The international journal of biochemistry & cell biology 2021 Dec;141:106091
The international journal of biochemistry & cell biology 2021 Dec;141:106091
Geniposide Ameliorated Dexamethasone-Induced Cholesterol Accumulation in Osteoblasts by Mediating the GLP-1R/ABCA1 Axis.
Zheng Y, Xiao Y, Zhang D, Zhang S, Ouyang J, Li L, Shi W, Zhang R, Liu H, Jin Q, Chen Z, Xu D, Wu L
Cells 2021 Dec 6;10(12)
Cells 2021 Dec 6;10(12)
Establishment and characterization of a highly metastatic human osteosarcoma cell line from osteosarcoma lung metastases.
Fan Z, Huang G, Zhao J, Li W, Lin T, Su Q, Yin J, Shen J
Journal of bone oncology 2021 Aug;29:100378
Journal of bone oncology 2021 Aug;29:100378
Polo Like Kinase 4 (PLK4) impairs human bone marrow mesenchymal stem cell (BMSC) viability and osteogenic differentiation.
Zhou B, Peng K, Wang G, Chen W, Kang Y
Biochemical and biophysical research communications 2021 Apr 16;549:221-228
Biochemical and biophysical research communications 2021 Apr 16;549:221-228
Higher BMP Expression in Tendon Stem/Progenitor Cells Contributes to the Increased Heterotopic Ossification in Achilles Tendon With Aging.
Dai G, Li Y, Liu J, Zhang C, Chen M, Lu P, Rui Y
Frontiers in cell and developmental biology 2020;8:570605
Frontiers in cell and developmental biology 2020;8:570605
Piperlongumine Attenuates High Calcium/Phosphate-Induced Arterial Calcification by Preserving P53/PTEN Signaling.
Shi W, Lu J, Li J, Qiu M, Lu Y, Gu J, Kong X, Sun W
Frontiers in cardiovascular medicine 2020;7:625215
Frontiers in cardiovascular medicine 2020;7:625215
Ethyl Acetate Fraction from Hedyotis diffusa plus Scutellaria barbata Suppresses Migration of Bone-Metastatic Breast Cancer Cells via OPN-FAK/ERK/NF-κB Axis.
Fang T, Yan YX, Yang Y, Lv YX, Chang QQ, Zhang DD
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3573240
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3573240
OPN Deficiency Increases the Severity of Osteoarthritis Associated with Aberrant Chondrocyte Senescence and Apoptosis and Upregulates the Expression of Osteoarthritis-Associated Genes.
Tian J, Cheng C, Kuang SD, Su C, Zhao X, Xiong YL, Li YS, Gao SG
Pain research & management 2020;2020:3428587
Pain research & management 2020;2020:3428587
R-Spondin 2 Induces Odontogenic Differentiation of Dental Pulp Stem/Progenitor Cells via Regulation of Wnt/β-Catenin Signaling.
Gong Y, Yuan S, Sun J, Wang Y, Liu S, Guo R, Dong W, Li R
Frontiers in physiology 2020;11:918
Frontiers in physiology 2020;11:918
Ginsenoside Rg3 attenuates ovariectomy-induced osteoporosis via AMPK/mTOR signaling pathway.
Zhang X, Huang F, Chen X, Wu X, Zhu J
Drug development research 2020 Nov;81(7):875-884
Drug development research 2020 Nov;81(7):875-884
RNA-seq analysis of palatal transcriptome changes in all-trans retinoic acid-induced cleft palate of mice.
Peng Y, Wang XH, Su CN, Qiao WW, Gao Q, Sun XF, Meng LY
Environmental toxicology and pharmacology 2020 Nov;80:103438
Environmental toxicology and pharmacology 2020 Nov;80:103438
Novel gene-specific translation mechanism of dysregulated, chronic inflammation reveals promising, multifaceted COVID-19 therapeutics.
Wang L, Muneer A, Xie L, Zhang F, Wu B, Mei L, Lenarcic EM, Feng EH, Song J, Xiong Y, Yu X, Wang C, Gheorghe C, Torralba K, Cook JG, Wan YY, Moorman NJ, Song H, Jin J, Chen X
bioRxiv : the preprint server for biology 2020 Nov 16;
bioRxiv : the preprint server for biology 2020 Nov 16;
T-cell death-associated gene 8 accelerates atherosclerosis by promoting vascular smooth muscle cell proliferation and migration.
Chen LD, Zhu WT, Cheng YY, Li ZH, Chen YQ, Yuan ZW, Lin CY, Jing DD, Liu ZQ, Yan PK
Atherosclerosis 2020 Mar;297:64-73
Atherosclerosis 2020 Mar;297:64-73
Exercise Promotes the Osteoinduction of HA/β-TCP Biomaterials via the Wnt Signaling Pathway.
Cheng L, Khalaf AT, Lin T, Ran L, Shi Z, Wan J, Zhou X, Zou L
Metabolites 2020 Mar 5;10(3)
Metabolites 2020 Mar 5;10(3)
Cortistatin ameliorates Ang II-induced proliferation of vascular smooth muscle cells by inhibiting autophagy through SSTR3 and SSTR5.
Wang Y, Zhang X, Chen W, Gao L, Li J, Song T, Chi J, Zhang X, Shi Z, Dong Y, Yin X, Liu Y
Life sciences 2020 Jul 15;253:117726
Life sciences 2020 Jul 15;253:117726
Quantitative alterations in bovine milk proteome from healthy, subclinical and clinical mastitis during S. aureus infection.
Maity S, Das D, Ambatipudi K
Journal of proteomics 2020 Jul 15;223:103815
Journal of proteomics 2020 Jul 15;223:103815
Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function.
Wang L, Yu P, Zhou B, Song J, Li Z, Zhang M, Guo G, Wang Y, Chen X, Han L, Hu S
Nature cell biology 2020 Jan;22(1):108-119
Nature cell biology 2020 Jan;22(1):108-119
The effect of extracellular matrix on the differentiation of mouse embryonic stem cells.
Ozdil B, Güler G, Acikgoz E, Kocaturk DC, Aktug H
Journal of cellular biochemistry 2020 Jan;121(1):269-283
Journal of cellular biochemistry 2020 Jan;121(1):269-283
SHED-derived conditioned exosomes enhance the osteogenic differentiation of PDLSCs via Wnt and BMP signaling in vitro.
Wang M, Li J, Ye Y, He S, Song J
Differentiation; research in biological diversity 2020 Jan-Feb;111:1-11
Differentiation; research in biological diversity 2020 Jan-Feb;111:1-11
Activation of cannabinoid receptor type 2-induced osteogenic differentiation involves autophagy induction and p62-mediated Nrf2 deactivation.
Xu A, Yang Y, Shao Y, Wu M, Sun Y
Cell communication and signaling : CCS 2020 Jan 15;18(1):9
Cell communication and signaling : CCS 2020 Jan 15;18(1):9
Modulation of the mechanosensing of mesenchymal stem cells by laser-induced patterning for the acceleration of tissue reconstruction through the Wnt/β-catenin signaling pathway activation.
Fu J, Liu X, Tan L, Cui Z, Liang Y, Li Z, Zhu S, Zheng Y, Kwok Yeung KW, Chu PK, Wu S
Acta biomaterialia 2020 Jan 1;101:152-167
Acta biomaterialia 2020 Jan 1;101:152-167
P38 MAPK signaling pathway mediates COM crystal-induced crystal adhesion change in rat renal tubular epithelial cells.
Qi S, Wang Q, Xie B, Chen Y, Zhang Z, Xu Y
Urolithiasis 2020 Feb;48(1):9-18
Urolithiasis 2020 Feb;48(1):9-18
Semaphorin 3A-hypoxia inducible factor 1 subunit alpha co-overexpression enhances the osteogenic differentiation of induced pluripotent stem cells-derived mesenchymal stem cells in vitro.
Li JY, Wang TT, Li C, Wang ZF, Li S, Ma L, Zheng LL
Chinese medical journal 2020 Feb 5;133(3):301-309
Chinese medical journal 2020 Feb 5;133(3):301-309
PKM2 suppresses osteogenesis and facilitates adipogenesis by regulating β-catenin signaling and mitochondrial fusion and fission.
Guo J, Ren R, Yao X, Ye Y, Sun K, Lin J, Wang G, Guo F, Xiao J, Xu T
Aging 2020 Feb 25;12(4):3976-3992
Aging 2020 Feb 25;12(4):3976-3992
Sustained delivery of PlGF-2(123-144*)-fused BMP2-related peptide P28 from small intestinal submucosa/polylactic acid scaffold material for bone tissue regeneration.
Xiong Z, Cui W, Sun T, Teng Y, Qu Y, Yang L, Zhou J, Chen K, Yao S, Shao Z, Guo X
RSC advances 2020 Feb 13;10(12):7289-7300
RSC advances 2020 Feb 13;10(12):7289-7300
Daphnetin ameliorates glucocorticoid-induced osteoporosis via activation of Wnt/GSK-3β/β-catenin signaling.
Wang Y, Chen J, Chen J, Dong C, Yan X, Zhu Z, Lu P, Song Z, Liu H, Chen S
Toxicology and applied pharmacology 2020 Dec 15;409:115333
Toxicology and applied pharmacology 2020 Dec 15;409:115333
Smooth muscle NADPH oxidase 4 promotes angiotensin II-induced aortic aneurysm and atherosclerosis by regulating osteopontin.
Yu W, Xiao L, Que Y, Li S, Chen L, Hu P, Xiong R, Seta F, Chen H, Tong X
Biochimica et biophysica acta. Molecular basis of disease 2020 Dec 1;1866(12):165912
Biochimica et biophysica acta. Molecular basis of disease 2020 Dec 1;1866(12):165912
Biomineralizaion of hydroxyapatite on polyethylene terephthalate artificial ligaments promotes graft-bone healing after anterior cruciate ligament reconstruction: An in vitro and in vivo study.
Cai J, Ai C, Chen J, Chen S
Journal of biomaterials applications 2020 Aug;35(2):193-204
Journal of biomaterials applications 2020 Aug;35(2):193-204
AKT/FOXO1 axis links cross-talking of endothelial cell and pericyte in TIE2-mutated venous malformations.
Si Y, Huang J, Li X, Fu Y, Xu R, Du Y, Cheng J, Jiang H
Cell communication and signaling : CCS 2020 Aug 31;18(1):139
Cell communication and signaling : CCS 2020 Aug 31;18(1):139
Effect of interleukin-33 on cementoblast-mediated cementum repair during orthodontic tooth movement.
Dong X, Feng J, Wen J, Bai D, Xu H
Archives of oral biology 2020 Apr;112:104663
Archives of oral biology 2020 Apr;112:104663
A novel Sprouty4-ERK1/2-Wnt/β-catenin regulatory loop in marrow stromal progenitor cells controls osteogenic and adipogenic differentiation.
Tian L, Xiao H, Li M, Wu X, Xie Y, Zhou J, Zhang X, Wang B
Metabolism: clinical and experimental 2020 Apr;105:154189
Metabolism: clinical and experimental 2020 Apr;105:154189
Icariin Protects Bone Marrow Mesenchymal Stem Cells Against Iron Overload Induced Dysfunction Through Mitochondrial Fusion and Fission, PI3K/AKT/mTOR and MAPK Pathways.
Yao X, Jing X, Guo J, Sun K, Deng Y, Zhang Y, Guo F, Ye Y
Frontiers in pharmacology 2019;10:163
Frontiers in pharmacology 2019;10:163
2,3,7,8-Tetrachlorodibenzo-p-dioxin promotes injury-induced vascular neointima formation in mice.
Guo S, Zhang R, Liu Q, Wan Q, Wang Y, Yu Y, Liu G, Shen Y, Yu Y, Zhang J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10207-10217
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10207-10217
Inhibiting effect of microRNA-187-3p on osteogenic differentiation of osteoblast precursor cells by suppressing cannabinoid receptor type 2.
Xu A, Yang Y, Shao Y, Wu M, Sun Y
Differentiation; research in biological diversity 2019 Sep-Oct;109:9-15
Differentiation; research in biological diversity 2019 Sep-Oct;109:9-15
Incorporated-bFGF polycaprolactone/polyvinylidene fluoride nanocomposite scaffold promotes human induced pluripotent stem cells osteogenic differentiation.
Abazari MF, Soleimanifar F, Enderami SE, Nematzadeh M, Nasiri N, Nejati F, Saburi E, Khodashenas S, Darbasizadeh B, Khani MM, Ghoraeian P
Journal of cellular biochemistry 2019 Oct;120(10):16750-16759
Journal of cellular biochemistry 2019 Oct;120(10):16750-16759
SPARC induces phenotypic modulation of human brain vascular smooth muscle cells via AMPK/mTOR-mediated autophagy.
Li T, Tan X, Zhu S, Zhong W, Huang B, Sun J, Li F, Wang Y
Neuroscience letters 2019 Nov 1;712:134485
Neuroscience letters 2019 Nov 1;712:134485
Osteopontin in the Pathogenesis of Aortic Dissection by the Enhancement of MMP Expressions.
Fan F, Zhou Q, Xu Z, Wang D
International heart journal 2019 Mar 20;60(2):429-435
International heart journal 2019 Mar 20;60(2):429-435
Citric acid enhances the physical properties, cytocompatibility and osteogenesis of magnesium calcium phosphate cement.
Wang S, Xu C, Yu S, Wu X, Jie Z, Dai H
Journal of the mechanical behavior of biomedical materials 2019 Jun;94:42-50
Journal of the mechanical behavior of biomedical materials 2019 Jun;94:42-50
The role and mechanism of transforming growth factor beta 3 in human myocardial infarction-induced myocardial fibrosis.
Xue K, Zhang J, Li C, Li J, Wang C, Zhang Q, Chen X, Yu X, Sun L, Yu X
Journal of cellular and molecular medicine 2019 Jun;23(6):4229-4243
Journal of cellular and molecular medicine 2019 Jun;23(6):4229-4243
Small molecule inhibitor of TGF-β signaling enables robust osteogenesis of autologous GMSCs to successfully repair minipig severe maxillofacial bone defects.
Shi A, Heinayati A, Bao D, Liu H, Ding X, Tong X, Wang L, Wang B, Qin H
Stem cell research & therapy 2019 Jun 13;10(1):172
Stem cell research & therapy 2019 Jun 13;10(1):172
Adipose-derived stem cells-conditioned medium improved osteogenic differentiation of induced pluripotent stem cells when grown on polycaprolactone nanofibers.
Soleimanifar F, Hosseini FS, Atabati H, Behdari A, Kabiri L, Enderami SE, Khani MM, Ardeshirylajimi A, Saburi E
Journal of cellular physiology 2019 Jul;234(7):10315-10323
Journal of cellular physiology 2019 Jul;234(7):10315-10323
Peroxisome Proliferator-Activated Receptor-γ Coactivator-1α Inhibits Vascular Calcification Through Sirtuin 3-Mediated Reduction of Mitochondrial Oxidative Stress.
Feng H, Wang JY, Yu B, Cong X, Zhang WG, Li L, Liu LM, Zhou Y, Zhang CL, Gu PL, Wu LL
Antioxidants & redox signaling 2019 Jul 1;31(1):75-91
Antioxidants & redox signaling 2019 Jul 1;31(1):75-91
Circulating osteopontin per tumor volume as a prognostic biomarker for resectable intrahepatic cholangiocarcinoma.
Zhou KQ, Liu WF, Yang LX, Sun YF, Hu J, Chen FY, Zhou C, Zhang XY, Peng YF, Yu L, Zhou J, Fan J, Wang Z
Hepatobiliary surgery and nutrition 2019 Dec;8(6):582-596
Hepatobiliary surgery and nutrition 2019 Dec;8(6):582-596
Effect of Hydroxyapatite Nanorods on the Fate of Human Adipose-Derived Stem Cells Assessed In Situ at the Single Cell Level with a High-Throughput, Real-Time Microfluidic Chip.
Hao M, He J, Wang C, Wang C, Ma B, Zhang S, Duan J, Liu F, Zhang Y, Han L, Liu H, Sang Y
Small (Weinheim an der Bergstrasse, Germany) 2019 Dec;15(51):e1905001
Small (Weinheim an der Bergstrasse, Germany) 2019 Dec;15(51):e1905001
Study of Bone Regeneration and Osteointegration Effect of a Novel Selective Laser-Melted Titanium-Tantalum-Niobium-Zirconium Alloy Scaffold.
Guo Y, Wu J, Xie K, Tan J, Yang Y, Zhao S, Wang L, Jiang W, Hao Y
ACS biomaterials science & engineering 2019 Dec 9;5(12):6463-6473
ACS biomaterials science & engineering 2019 Dec 9;5(12):6463-6473
Efficient osteogenic differentiation of the dental pulp stem cells on β-glycerophosphate loaded polycaprolactone/polyethylene oxide blend nanofibers.
Hosseini FS, Enderami SE, Hadian A, Abazari MF, Ardeshirylajimi A, Saburi E, Soleimanifar F, Nazemisalman B
Journal of cellular physiology 2019 Aug;234(8):13951-13958
Journal of cellular physiology 2019 Aug;234(8):13951-13958
Quantitative proteomics of milk whey reveals breed and season specific variation in protein abundance in Holstein Friesian cow and Murrah buffalo.
Maity S, Ambatipudi K
Research in veterinary science 2019 Aug;125:244-252
Research in veterinary science 2019 Aug;125:244-252
Effect of microRNA-21 on hypoxia-inducible factor-1α in orthodontic tooth movement and human periodontal ligament cells under hypoxia.
Zhang X, Chen D, Zheng J, Deng L, Chen Z, Ling J, Wu L
Experimental and therapeutic medicine 2019 Apr;17(4):2830-2836
Experimental and therapeutic medicine 2019 Apr;17(4):2830-2836
Promoting osteogenic differentiation of human-induced pluripotent stem cells by releasing Wnt/β-catenin signaling activator from the nanofibers.
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Journal of cellular biochemistry 2019 Apr;120(4):6339-6346
Journal of cellular biochemistry 2019 Apr;120(4):6339-6346
Validation of Phosphodiesterase-10 as a Novel Target for Pulmonary Arterial Hypertension via Highly Selective and Subnanomolar Inhibitors.
Huang YY, Yu YF, Zhang C, Chen Y, Zhou Q, Li Z, Zhou S, Li Z, Guo L, Wu D, Wu Y, Luo HB
Journal of medicinal chemistry 2019 Apr 11;62(7):3707-3721
Journal of medicinal chemistry 2019 Apr 11;62(7):3707-3721
New Application of Psoralen and Angelicin on Periodontitis With Anti-bacterial, Anti-inflammatory, and Osteogenesis Effects.
Li X, Yu C, Hu Y, Xia X, Liao Y, Zhang J, Chen H, Lu W, Zhou W, Song Z
Frontiers in cellular and infection microbiology 2018;8:178
Frontiers in cellular and infection microbiology 2018;8:178
Downregulated Expression of Solute Carrier Family 26 Member 6 in NRK-52E Cells Attenuates Oxalate-Induced Intracellular Oxidative Stress.
Jiang H, Gao X, Gong J, Yang Q, Lan R, Wang T, Liu J, Yin C, Wang S, Liu Z
Oxidative medicine and cellular longevity 2018;2018:1724648
Oxidative medicine and cellular longevity 2018;2018:1724648
Osteopontin is essential for IL-1β production and apoptosis in peri-implantitis.
Che C, Liu J, Yang J, Ma L, Bai N, Zhang Q
Clinical implant dentistry and related research 2018 Jun;20(3):384-392
Clinical implant dentistry and related research 2018 Jun;20(3):384-392
Hypoxia-Inducible Factor-1α (HIF-1α) Expression on Endothelial Cells in Juvenile Nasopharyngeal Angiofibroma: A Review of 70 cases and Tissue Microarray Analysis.
Song X, Yang C, Zhang H, Wang J, Sun X, Hu L, Liu Z, Wang D
The Annals of otology, rhinology, and laryngology 2018 Jun;127(6):357-366
The Annals of otology, rhinology, and laryngology 2018 Jun;127(6):357-366
Nesfatin-1 promotes VSMC migration and neointimal hyperplasia by upregulating matrix metalloproteinases and downregulating PPARγ.
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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:711-717
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:711-717
Negative pressure wound therapy promotes muscle-derived stem cell osteogenic differentiation through MAPK pathway.
Liu H, Zheng X, Chen L, Jian C, Hu X, Zhao Y, Li Z, Yu A
Journal of cellular and molecular medicine 2018 Jan;22(1):511-520
Journal of cellular and molecular medicine 2018 Jan;22(1):511-520
Teniposide regulates the phenotype switching of vascular smooth muscle cells in a miR-21-dependent manner.
Han H, Yang S, Liang Y, Zeng P, Liu L, Yang X, Duan Y, Han J, Chen Y
Biochemical and biophysical research communications 2018 Dec 2;506(4):1040-1046
Biochemical and biophysical research communications 2018 Dec 2;506(4):1040-1046
Myricetin ameliorates glucocorticoid-induced osteoporosis through the ERK signaling pathway.
Fan S, Gao X, Chen P, Li X
Life sciences 2018 Aug 15;207:205-211
Life sciences 2018 Aug 15;207:205-211
Osteopontin contributes to effective neutrophil recruitment, IL-1β production and apoptosis in Aspergillus fumigatus keratitis.
Zhao G, Hu M, Li C, Lee J, Yuan K, Zhu G, Che C
Immunology and cell biology 2018 Apr;96(4):401-412
Immunology and cell biology 2018 Apr;96(4):401-412
The prognostic value of osteopontin in limited-stage small cell lung cancer patients and its mechanism.
Liu F, Bai C, Guo Z
Oncotarget 2017 Sep 19;8(41):70084-70096
Oncotarget 2017 Sep 19;8(41):70084-70096
The protective effect of PFTα on alcohol-induced osteonecrosis of the femoral head.
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Oncotarget 2017 Nov 21;8(59):100691-100707
Oncotarget 2017 Nov 21;8(59):100691-100707
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Nanoscale 2017 May 25;9(20):6765-6776
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Zhu R, Chen YX, Ke QF, Gao YS, Guo YP
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Microarray-based detection and expression analysis of new genes associated with drug resistance in ovarian cancer cell lines.
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Cancer medicine 2017 Aug;6(8):1976-1987
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MicroRNA-99a inhibits insulin-induced proliferation, migration, dedifferentiation, and rapamycin resistance of vascular smooth muscle cells by inhibiting insulin-like growth factor-1 receptor and mammalian target of rapamycin.
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Biochemical and biophysical research communications 2017 Apr 29;486(2):414-422
Biochemical and biophysical research communications 2017 Apr 29;486(2):414-422
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American journal of cancer research 2016;6(9):1873-1889
American journal of cancer research 2016;6(9):1873-1889
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Lupus 2016 Dec;25(14):1577-1586
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Stem cells international 2015;2015:565732
Stem cells international 2015;2015:565732
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eLife 2015 Nov 13;4
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Oncology reports 2014 Oct;32(4):1550-6
Oncology reports 2014 Oct;32(4):1550-6
Protective effects of epigallocatechin gallate (EGCG) on streptozotocin-induced diabetic nephropathy in mice.
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Acta histochemica 2014 Oct;116(8):1210-5
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Characterization of a micro-roughened TiO2/ZrO2 coating: mechanical properties and HBMSC responses in vitro.
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Acta biochimica et biophysica Sinica 2014 Jul;46(7):572-81
Acta biochimica et biophysica Sinica 2014 Jul;46(7):572-81
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Stem cells translational medicine 2014 Dec;3(12):1504-13
Stem cells translational medicine 2014 Dec;3(12):1504-13
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse kidney tissue were subjected to SDS PAGE followed by western blot with 22952-1-AP( OPN, SPP1 Antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human stomach cancer using 22952-1-AP(OPN, SPP1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Osteopontin antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human Osteopontin. This antibody recognizes human, mouse antigen. The Osteopontin antibody has been validated for the following applications: ELISA, IHC, WB analysis.