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- Antigen structure
- References [576]
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- Product number
- 22952-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#22952-1-AP, RRID:AB_2783651
- Product name
- Osteopontin antibody
- Antibody type
- Polyclonal
- Description
- Osteopontin antibody (Cat. #22952-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat, mouse and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Functionalized magnetic hydrogel encapsulation of human dental follicle stem cells under a static magnetic field enhances multi-site bone regeneration.
A near-infrared regulated programmable multi-mode periosteum scaffold for sequential healing of infected bone defects.
Study on the pro-inflammatory mechanism mediated by the RANK-SPP1 axis in macrophage immunomodulation during atherosclerosis.
Masking macrophage injury sensing via poly I sustained release system reduces inflammation and fibrosis.
Single-cell and spatial transcriptomics identify PGK1-sensitized hypoxia macrophages as a therapeutic target to overcome PDT resistance in glioma.
TRAP5 Inhibition Targeting Scar-Associated Macrophages Ameliorates Acute Kidney Injury to Chronic Kidney Disease Transition.
Isoliquiritigenin restores bone homeostasis in osteoporotic rats by enhancing BMSCs osteogenesis via ERK1/2-mTOR-HIF-1α-glycolytic axis and suppressing inflammation.
Tumor-intrinsic redox programming drives an SPP1-CD44 axis of immune suppression in uveal melanoma.
Ciliary IFT88 inhibits intervertebral disc degeneration under excessive mechanical stress by regulating endplate cartilage calcification.
Composite hydrogel-microsphere delivery system promotes early nerve-mediated bone regeneration and late-stage mechanotransduction-driven bone remodeling via sequential release of NGF and Yoda1.
LncRNA GAS5 regulates osteogenic differentiation of human periodontal ligament stem cells through miR-23b-3p/STAT5B axis.
CGRP Enhances the Regeneration of Bone Defects by Regulating Bone Marrow Mesenchymal Stem Cells Through Promoting ANGPTL4 Secretion by Bone Blood Vessels.
NFS1 Regulates IDH2 to Attenuate Abdominal Aortic Aneurysms via Interacting With SP2.
The TRAF6/SPP1 axis participates in osteoarthritis progression through regulating the catabolism and anabolism of cartilage matrix.
Lung Adenocarcinoma Promotes NETosis via the NPM1-TNFAIP6-CD44-SPP1 Axis.
Identification of hub targets involved in carotid atherosclerosis through bioinformatics and machine learning approaches.
A Cross-Disease Microglial Transcriptional Program Characterizes Neurodegeneration and Highlights SPP1 as a Biomarker.
Geometry-driven immunomodulation in 3D-printed bioceramics: Negative curvature promotes macrophage M2 polarization via Ras-MAPK/HIF-1α signaling for vascularized osteogenesis.
TGF-β drives pulmonary fibrosis through dual dysregulation of TNF pathway transcription and splicing.
Curcumin modulates the function of SPP1+ macrophages via NF-κB signaling to alleviate endometriosis.
Modular de- and re-construction of vascularized osteochondral tissues in an Organ-on-Chip dual-compartment platform.
Ginsenoside Ro alleviated cuproptosis induced by high oxalate via inhibiting zinc transporter ZnT1 in renal tubular epithelial cells.
Microenvironment-activatable nanoagent for real-time NIR-II monitoring and targeted therapy of arterial restenosis.
Targeting astrocytic CLC2(CLCN2) restores myelin regeneration through inhibition of SPP1/CD44 signaling pathway in leukoencephalopathy.
Melatonin promotes osteogenic differentiation of BMSCs by regulating circZFAND1/miR-433-3p/DKK1 pathway through melatonin receptor-dependent m6A modification of circZFAND1.
Proteomics analysis of serum extracellular vesicle identifies UCHL1 as a potential therapeutic target for high grade serous ovarian cancer.
Revolutionizing nephrocalcinosis treatment: IL-10 engineered macrophages as a novel therapeutic approach.
CA9+ cancer-associated fibroblasts cooperate with SPP1+ tumor-associated macrophages driving immune resistance in triple-negative breast cancer.
Integrated single-cell and bulk RNA sequencing unravels neutrophil heterogeneity and validates SPP1 as a prognostic biomarker in cervical cancer.
Pathology-tailored nanotherapy via Galectin-3-targeted and triple-responsive nanoparticles enables multimodal therapy against aortic dissection.
Injectable hydrogels for osteomyelitis treatment induce metabolic reprogramming for protection against reinfection.
Pilose antler peptide enhances diabetic fracture healing by modulating the CREB-Smad2/3-Runx2 signaling axis.
Targeted inflammatory microenvironment remodeling and NIR-II photothermal therapy for abdominal aortic aneurysm.
WTAP Contributes to Periodontitis Pathogenesis by Promoting PDLSC Senescence and Impairing Osteogenic Differentiation via m6A-Dependent Regulation of TP53BP1.
Efferocytosis-Driven Polyamine Metabolism in Macrophages Enhances Cancer Stem Cell Enrichment after Chemotherapy in Ovarian Cancer.
Citrate-coated Prussian blue nanozyme hitchhikes neutrophils to ameliorate calcium oxalate crystal-induced kidney injury via inhibiting pyroptosis and NETosis.
Single-Nucleus RNA Sequencing Reveals SPP1(+) Macrophages Induce Cardiomyocyte Apoptosis to Promote Atrial Fibrillation Susceptibility.
C5aR1(+) microglia exacerbate neuroinflammation and cerebral edema in acute brain injury.
ANGPTL8 accelerates bone loss in diabetic mice by promoting osteoclastic differentiation and inhibiting osteoblastic differentiation through AMPK pathway-mediated metabolic reprogramming.
Supramolecular delivery of senolytics enables targeted anti-senescence therapy and accelerated fracture healing.
Discovery of 8-quinolinesulfonamide phenylimidazole-based PKM2 agonists for the prevention and delay of aortic dissection.
The p75 neurotrophin receptor controls the skeletal stem cell niche through sensory innervation.
The promoting roles of GLP1R and GIPR in stemness maintenance and multiple lineage-specific differentiation of PDLSCs.
Pulmonary macrophage-targeted RNAi and mRNA co-delivery via SORT lipid nanoparticles enhances immunotherapy in lung cancer.
Integration of Multi-Omics and Machine Learning Identifies TGFB1 and SERPINE1 as Biomarkers of Vascular Smooth Muscle Cell Senescence in Intracranial Aneurysms.
FUNDC2 contributes to hypertensive vascular remodeling by regulating mitochondrial dynamics and ferroptosis in perivascular adipose tissue.
A composite hydrogel enables the spatiotemporal delivery of distinct cytokines to drive the native vascularized bone regeneration.
PRSS22 inhibits HMOX1-mediated ferroptosis and induces osteopontin cleavage to promote M2 macrophage polarization and colitis-associated carcinogenesis.
3D-printed titanium scaffolds coated with a multifunctional photothermal-responsive hydrogel promote osteoporotic bone defect repair.
Graphene oxide coating on two-dimensional glass substrates and three-dimensional zirconia scaffolds for bone tissue regeneration.
Ultrasound-activated piezoelectric Silk-PVDF hydrogel reprograms the osteoimmune microenvironment via NRF2 signaling for accelerated bone regeneration.
Dual-release 3D-printed porous Ti-6Al-4V implant with drug-eluting photothermal micro-nanotopographies: combating osteosarcoma recurrence, infections, and enhancing osteogenesis.
Sparcl1 mitigates abdominal aortic aneurysm through inhibiting lymphangiogenesis-mediated TLS formation.
ZFP36L1 promotes non-small cell lung cancer progression under hypoxia by modulating CXCL9:SPP1 polarity: A single-cell transcriptomic study.
Bioinspired Engineering of Streamlined Skeletal Interoception: Neural Bioprinted Piezoelectric Scaffolds for Neuro-Vascularized Bone Regeneration.
Sr²⁺-coordinated asiatic acid/silk fibroin hybrid hydrogels for enhanced osteogenesis and antibacterial therapy in infective bone defects.
A single-cell multiomic analysis identifies molecular and gene-regulatory mechanisms dysregulated in developing Down syndrome neocortex.
Synergistic Antibacterial and Osteogenic Activities of Cu/Sr-Empowered 13-93 Bioglass in PMMA Composites for Sequential Promotion of Infectious Osseointegration.
QiangGuYin-containing serum improves osteogenic differentiation via regulating osteoclast-derived exosomal miR-27b-3p.
Loss of Gαq reshapes fibroblast traits and drives tumor-stroma remodeling in oral cancer progression.
A Noninvasive Menstrual Blood-Based Diagnostic Platform for Endometriosis Using Digital Droplet Enzyme-Linked Immunosorbent Assay and Single-Cell RNA Sequencing.
Novel lncRNA LncMSTRG.11341.25 Promotes Osteogenic Differentiation of Human Bone Marrow Stem Cells via the miR-939-5p/PAX8 Axis.
Identification of pivotal genes and crucial pathways in liver fibrosis through WGCNA analysis.
A Biodegradable Zinc Alloy Membrane with Regulation of Macrophage Polarization for Early Vascularized Bone Regeneration.
A pH-Responsive Polyetheretherketone Implant Modified with a Core-Shell Metal-Organic Framework to Promote Antibacterial and Osseointegration Abilities.
Endothelial TIE2 Mutation Induced Contraction Deficiency of Vascular Smooth Muscle Cells via Phenotypic Transition Regulation in Venous Malformations.
Integrin β3-mediated platelet extracellular vesicle adhesion facilitates vascular smooth muscle cell dysfunction in postinjury intimal hyperplasia.
Ti(3)C(2)Tx MXene Potentiates PSAT1-Mediated Osteogenesis Through miR-665/GSK-3β/β-Catenin Axis to Counteract Inflammation-Induced Bone Loss.
Osteopontin as a Novel Biomarker in Distinguishing Chronic Rhinosinusitis with Nasal Polyp Endotypes and Predicting Disease Severity.
Single-Cell RNA Sequencing Reveals Microglial Heterogeneity and Functional States After Cerebral Ischemia-Reperfusion Injury.
Single-cell RNA-seq reveals a repair pattern in cystic lesions in steroid induced osteonecrosis of the femoral head.
Identification of a stromal immunosuppressive barrier orchestrated by SPP1(+)/C1QC(+) macrophages and CD8(+) exhausted T cells driving gastric cancer immunotherapy resistance.
Identification of immune-related diagnostic genes and immune cell infiltration in aseptic loosening of prostheses after total hip arthroplasty by integrated bioinformatics analysis and experimental confirmation.
The dual role of CXCL9/SPP1 polarized tumor-associated macrophages in modulating anti-tumor immunity in hepatocellular carcinoma.
O-GlcNAcylation-dependent liquid-liquid phase separation regulates the nuclear translocation of YAP to exacerbate vascular neointimal hyperplasia.
Prognostic value and immune infiltration of anoikis-related genes in osteosarcoma.
METTL14 promotes TBK1 mRNA stability through IGF2BP3-recognized m6A modification and enhances mitophagy in BMSCs.
Single-cell transcriptomic analyses provide insights into SPP1(+) TAM-mediated immune suppression and CD8(+) T cell dysfunction in lung cancer.
Mechanism of Piezo1 regulating chondrocyte mitochondrial function and promoting fracture healing through β-catenin/LARS2 signaling pathway.
Targeting USP21 to inhibit abdominal aortic aneurysm progression by suppressing the phenotypic transition of vascular smooth muscle cells.
In situ construction of ossification micro-units for critical bone regeneration via sustained lifting of epigenetic suppression.
Dimethyloxalylglycine regulates osteogenesis of dental pulp stem cells through PI3K/AKT signaling pathways.
RNF213 Knockdown and Inflammation Promote Angiogenesis and Phenotype Switching by JAK2/STAT3 Pathway in Moyamoya Disease.
Gut microbiota diversity and metabolomics analysis of curcumin's alleviation of abdominal aortic aneurysm progression.
PKA-driven SPP1 activation as a novel mechanism connecting the bone microenvironment to prostate cancer progression.
GNAS/PKA signaling promotes aberrant osteochondral differentiation of Gli1(+) tendon sheath progenitors.
Dual stimulus-responsive dECM cryogel sequentially regulate bone microenvironment for one-step surgical therapy of chronic osteomyelitis.
Synergistic exacerbation of periprosthetic osteolysis by inflammatory bowel disease and titanium ions: Impaired osteogenesis of BMSCs via PI3K/AKT signaling.
TGF-β1/IL-11 positive loop between renal tubular epithelial cell and fibroblast promotes the ectopic calcification of renal interstitial fibroblasts in rats.
Profibrotic impact of PAD4-driven macrophage extracellular traps in ulcerative colitis.
A Novel Injectable Composite Hydrogel HAp-GelMA Co-Doped Magnesium/Zinc Promotes Bone Generation and Angiogenesis Synergistically.
POSTN-Mediated Interplay of M1 Polarized Macrophage with Tendon-Derived Stem Cells to Drive Traumatic Heterotopic Ossification Formation through PTK7/ATK Signaling?
Single-cell RNA sequencing reveals that Danggui Buxue Tang decoction facilitates wound healing after anal fistula by promoting M2 macrophage polarization.
Linoelaidic acid alleviates COM-induced kidney injury and crystal deposition via the PPARγ/MAPK signaling pathway.
Pak4-mediated crosstalk between necroptotic macrophages and tendon stem/progenitor cells contributes to traumatic heterotopic ossification formation.
BMDMs in metabolic memory impair fracture healing in diabetes.
Altered pattern of proteolysis in rhegmatogenous retinal detachment by mining of N-termini datasets from vitreous humor proteome.
A Positive Feedback Loop Between SPP1 (+)Macrophages and Tumor Cells Promotes Head and Neck Squamous Cell Carcinoma Progression.
Bicontinuous Interconnected Porous Biomaterials for Tissue Engineering and Regeneration.
Osteoblast-Mesenchymal Stem Cell Coculture Drives In Vitro Osteogenesis in 3D Bioprinted Periosteum.
Biomimetic Scaffolds with Dual Gradients of Biological Effectors for Tendon-to-Bone Repair.
MYST1-Mediated Lysine Acetylation Stabilizes KLF4 to Promote Intimal Hyperplasia.
Antihypertension and Improvement Effects of Hexapeptide APPLRP on Exosomes-Mediated Vascular Endothelial Inflammation in Spontaneously Hypertensive Rats.
FABP3 Mediates Lipid Droplet Accumulation and Adhesive Capacity in Bovine Endometrial Epithelial Cells via PGE(2)/PTGER4/PPAR Axis.
Deferoxamine improves femoral trochlear dysplasia following patellar dislocation through HIF-1α/VEGF-mediated angiogenesis-osteogenesis coupling.
Assessing the toxicological effects of exposure to environmental pollutants PET-MPs on vascular diseases: insights from network toxicology, molecular docking, molecular dynamics, and experimental validation.
Berberine ameliorates atherosclerosis by inhibiting the phenotypic transition of vascular smooth muscle cells via suppression of the JAK2/STAT3 signaling pathway.
Curcumenol exerts anti-pulmonary fibrosis effects through modulation of the immune signature target SPP1: based on comprehensive bioinformatics and experiments validation.
Single-cell and spatial RNA sequencing identify divergent microenvironments and progression signatures in early- versus late-onset prostate cancer.
An ultrasound-driven PLGA/Zn-KNN hybrid piezoelectric scaffold with direct and immunoregulatory antibacterial activity for bone infection.
JOSD2 inhibits angiotensin II-induced vascular remodeling by deubiquitinating and stabilizing SMAD7.
A novel 5-differentially expressed gene (DEG) signature predicting the prognosis in patients with metastatic liver malignancies and the prognostic and therapeutic potential of SPP1.
Smooth muscle cell Piezo1 is essential for phenotypic switch and neointimal hyperplasia.
Integrated multi-omics characterization of neuroblastoma with bone or bone marrow metastasis.
Preparation, Physicochemical Characterization, and In Vitro and In Vivo Osteogenic Evaluation of Reinforced PLLA-PLCL/HA Resorbable Membranes.
Melatonin Promotes Osteogenic Differentiation of Rat Adipose-Derived Stem Cells via the p38/MAPK Signaling Pathway.
Mineralocorticoid receptor antagonism attenuates arteriovenous fistula stenosis by modulating the phenotype of vascular smooth muscle cells.
PIASy deficiency mitigates thoracic aortic aneurysm formation via the TGF-β/Smad2/3 pathway.
IGF-1 signaling pathway activation promotes axonal regeneration and repair: A mechanism study on catalpol-induced functional recovery after ischemic stroke.
An Asymmetric Zn Membrane with Degradability, Antimicrobial, and Bone Immunomodulation for Guided Bone Regeneration.
Geniposide ameliorates cholesterol accumulation and promotes osteoblast differentiation by mediating the GLP-1R/AMPK/SREBP2 pathway.
Orai1 Participates in Coronary Artery Dysfunction Caused by Hypertension via Regulating Smooth Muscle Cell Phenotype Transformation.
Direct microglia replacement reveals pathologic and therapeutic contributions of brain macrophages to a monogenic neurological disease.
High-Entropy Alloy/Zinc Sulfide Heterojunction-Based Hydrogel for Eliminating Bacteria and Stimulating Osteoblast Response.
Low-frequency, mild-gradient chronic intermittent hypoxia still induces liver fibrogenesis in mice on a high-fat diet.
5,7-Dihydroxy-4-Methylcoumarin enhances osteogenesis and ameliorates osteoporosis via the AKT1 pathway.
SERCA2 dysfunction accelerates angiotensin II-induced aortic aneurysm and atherosclerosis by induction of oxidative stress in aortic smooth muscle cells.
The Effects of different forms of exercise during the early life on the bone microstructure of ovariectomized mice.
MOF-818 Nanozyme Suppresses Calcium Oxalate Kidney Stones by Alleviating Oxidative Stress and Inflammatory Injury.
A Highly Bioactive Organic-Inorganic Nanoparticle for Activating Wnt10b Mediated Osteogenesis by Specifically Anchor CCN3 Protein.
Enhanced Vascular Smooth Muscle Cell and Extracellular Matrix Repair Using a Metal-Organic Framework-Based Co-Delivery System for Abdominal Aortic Aneurysm Therapy.
METTL3-mediated m6A modification of circSTAT6 modulates miR-188-3p/Beclin1 axis to promote osteogenic differentiation of mesenchymal stem cells.
ROS-responsive nanoparticles with selenomethionine for ferroptosis modulation in abdominal aortic aneurysm.
Graphene oxide andin-situcarbon reinforced hydroxyapatite scaffolds via ultraviolet-curing 3D printing technology with high osteoinductivity for bone regeneration.
Vdr mediates Wnt signaling pathway to regulate odontoblasts differentiation during dentin apposition.
miR-138-5p inhibits healing of femoral fracture osteogenesis in rats by modulating osteoblast differentiation via SIRT1/FOXO1 axis.
Static Topographical Cue Combined with Dynamic Fluid Stimulation Enhances the Macrophage Extracellular Vesicle Yield and Therapeutic Potential for Bone Defects.
NPC1L1 Drives Osteoporosis by Activating the C/EBPα/Cyp27a1/27-Hydroxycholesterol Axis: A Novel Therapeutic Target for Bone Loss.
Magnetically bioprinted anisotropic hydrogels promote BMSC osteogenic differentiation for bone defect repair.
A novel strategy for bone defect repair: Stromal cell-derived factor 1α sustained-release acellular fish scale scaffolds combined with injection of bone marrow mesenchymal stem cells promote bone regeneration.
Sequential SDF-1/CGRP-releasing smart composite hydrogel promotes osteoporotic fracture healing by targeting sensory nerve-regulated bone remodeling.
Harnessing engineered exosomes as METTL3 carriers: Enhancing osteogenesis and suppressing lipogenesis in bone marrow mesenchymal stem cells for postmenopausal osteoporosis treatment.
Injectable bioresponsive bone adhesive hydrogels inhibit NLRP3 inflammasome on demand to accelerate diabetic fracture healing.
Inhibition of SFRP1 by microRNA‑206‑3p may be the underlying cause of osteosarcopenia.
Macrophages-derived small extracellular vesicles regulate chondrocyte proliferation and affect osteoarthritis progression via upregulating Osteopontin expression.
Injectable Alginate/β-TCP Composite Hydrogel Incorporating P34HB/MgO+PEG Coaxial Electrospun Microfibers for Minimally Invasive Treatment of Osteonecrosis.
SOX3 facilitates granulosa cell proliferation and suppresses cell apoptosis through modulating PI3K/AKT pathway by targeting SPP1.
TAMs-derived SPP1, regulated by HIF-1α/STAT3 signaling pathway, influences colorectal cancer malignant progression by activation of EMT via integrin αvβ3.
STAT3-controlled CHI3L1/SPP1 positive feedback loop demonstrates the spatial heterogeneity and immune characteristics of glioblastoma.
Mesenchymal stem cells attenuate hyperoxaluria-induced kidney injury and crystal depositions via inhibiting the activation of NLRP3 inflammasome.
The Piezo1/Extracellular Signal-Regulated Kinase Signal Pathway Regulates Proliferation and Migration of Aortic Vascular Smooth Muscle Cells and Participates in Thoracic Aortic Aneurysm.
Colchicine inhibits vascular calcification by suppressing inflammasome activation through the enhancement of the Sirt2-PP2Ac signaling pathway.
UCP1 prevents the formation of thoracic aortic aneurysms and dissection by inhibiting the TLR4/NLRP3/IL-1β signaling pathway and VSMC phenotype switching in mice.
Cytoplasmic and nuclear NFATc3 cooperatively contributes to vascular smooth muscle cell dysfunction and drives aortic aneurysm and dissection.
Quercetin nanoformulation-embedded hydrogel inhibits osteopontin mediated ferroptosis for intervertebral disc degeneration alleviation.
The role of glucocorticoids in hepatocellular carcinoma through integrated bioinformatics analysis and experimental validation.
Single-cell transcriptomics identifies PDGFRA(+) progenitors orchestrating angiogenesis and periodontal tissue regeneration.
Gut microbiota-derived indole-3-acetic acid ameliorates calcium oxalate renal stone formation via AHR/NF‑κB axis.
Single-Cell and Spatial Transcriptomics Reveal a Tumor-Associated Macrophage Subpopulation that Mediates Prostate Cancer Progression and Metastasis.
Identification and verification of oxidative stress-related genes in the diagnosis of osteoporosis.
Multiomic identification of senescent stem cell populations critical for osteoarthritis progression and therapy in subchondral bones.
Secreted phosphoprotein 1 promotes the activation of keloid fibroblasts via the CD44/TGF-β1/Smad pathway.
Negative Air Ions Attenuate Nicotine-Induced Vascular Endothelial Dysfunction by Suppressing AP1-Mediated FN1 and SPP1.
Integrated Single-Cell Analysis Dissects Regulatory Mechanisms Underlying Tumor-Associated Macrophage Plasticity in Hepatocellular Carcinoma.
Apoptotic extracellular vesicles derived from human dental pulp stem cells facilitate periodontal tissue regeneration.
Single-cell transcriptomic analysis of the senescent microenvironment in bone metastasis.
Moderate static magnetic field regulates iron metabolism and salvage bone loss caused by iron accumulation.
NIR-stimulated rGO-HAMC hydrogel enhances fracture healing through regulating B-cell signaling.
Magnesium-Impregnated Membrane Promotes Bone Regeneration in Rat Skull Defect by N-Linked Glycosylation of SPARC via MagT1.
Naked cuticle homolog 2 controls the differentiation of osteoblasts and osteoclasts and ameliorates bone loss in ovariectomized mice.
Tea Polyphenol-Derived Carbon Dots Alleviate Abdominal Aortic Aneurysm Progression by Mitigating Oxidative Stress and Ferroptosis.
Dentin tubules as a long-term sustained release carrier to accelerate bone repair by loading FTY720.
Shen Qi Wan regulates OPN/CD44/PI3K pathway to improve airway inflammation in COPD: Network pharmacology, bioinformatics, and experimental validation.
MSC-EXs inhibits uranium nephrotoxicity by competitively binding key proteins and inhibiting ROS production.
Single-cell RNA sequencing analysis reveals the dynamic changes in the tumor microenvironment during NMIBC recurrence.
Doxorubicin and topotecan resistance in ovarian cancer: Gene expression and microenvironment analysis in 2D and 3D models.
Synergistic Enhancement of Antibacterial and Osteo-Immunomodulatory Activities of Titanium Implants via Dual-Responsive Multifunctional Surfaces.
SPP1-ITGα5/β1 Accelerates Calcification of Nucleus Pulposus Cells by Inhibiting Mitophagy via Ubiquitin-Dependent PINK1/PARKIN Pathway Blockade.
Low-Intensity Pulsed Ultrasound Responsive Scaffold Promotes Intramembranous and Endochondral Ossification via Ultrasonic, Thermal, and Electrical Stimulation.
Regulation of macrophage-mediated osteogenesis by kaempferol liposomes in trauma-induced heterotopic ossification.
Mechanistic studies of Ca(2+)-induced classical pyroptosis pathway promoting renal adhesion on calcium oxalate kidney stone formation.
Cordycepin ameliorates spaceflight-induced osteoporosis by preventing BMSCs oxidative stress and senescence via interacting with PI3K p110α and regulating PI3K/Akt/FOXO3 signalling.
SPP1-mediated crosstalk between macrophage and fibroblasts promotes benign airway stenosis.
Nano MgO loaded thermosensitive HPCH@HA hydrogel accelerates in situ bone repair through osteoimmunomodulation while enhancing angiogenesis and osteogenesis.
Ceria nanoparticles guard against glucocorticoid induced bone homeostasis imbalance through the promotion of osteogenesis and inhibition of osteoclastogenesis.
High Shear Stress-Induced Endothelial Piezo1 Downregulation Promotes Intracranial Aneurysm Formation via the PDGF-BB/PDGFRβ Paracrine Signaling Pathway.
Cuttlebone inspired "S"-grooved topological structures facilitate osteogenic differentiation through the Rap1-ERK pathway.
Lumican from DESC spheroids enhances odontoblastic differentiation of SCAPs.
Neutrophil extracellular traps promote bone loss in type 1 diabetes via suppression of the FN1-PI3K/Akt signaling axis.
Injectable Nanocomposite Biomaterial for 3D Printing of Personalized Matrices and Their Use in Bioreactors for Bioengineering Advanced Cell Culture Models.
Single-cell identification of an endothelial cell proximal SPP1(+) macrophage population defines the metastatic vascular niche in lymph nodes.
Manganese dioxide coupled metal-organic framework as mitophagy regulator alleviates periodontitis through SIRT1-FOXO3-BNIP3 signaling axis.
Bgh/GelMA/CMCS hydrogel with bone MSC-EVs for lunate defect repair.
Vascular Smooth Muscle-Secreted Exosomal X26nt Impedes Atherosclerosis Progression via the c-FOS/XBP1/SOD1 Axis.
Hypoxanthine Promotes Pulmonary Vascular Remodeling and Adenosine Deaminase Is a Therapeutic Target for Pulmonary Hypertension.
TCF7L2 regulates GPX4 to resist ferroptosis and enhance osteogenesis in mouse mesenchymal stem cells.
M2c Macrophages Mediate YAP1 to Promote Vascularized Bone Regeneration in Distraction Osteogenesis.
Laboratory investigation of METTL7A driving MSC osteogenic differentiation through YAP1 translation enhancement via eIF4F recruitment.
Cerium-Containing Mesoporous Bioactive Glass Nanoparticles Reinforced 3D-Printed Bioceramic Scaffolds toward Enhanced Mechanical, Antioxidant, and Osteogenic Activities for Bone Regeneration.
Isovaleroylbinankadsurin A ameliorates atherosclerosis and restenosis by promoting LXRα signaling pathway and inhibiting TGF-β1 and FHL1 signaling pathways.
Ganoderic Acid A Prevented Osteoporosis by Modulating the PIK3CA/p-Akt/TWIST1 Signaling Pathway.
Exonic CircGUCY1A2 inhibits pulmonary artery smooth muscle cells phenotypic switching via regulating O-glycosylation of COL3A1 in pulmonary hypertension.
Cathepsin D inhibits AGEs-induced phenotypic transformation in vascular smooth muscle cells.
USP2-induced upregulation of LEF1 through deubiquitination relieves osteoporosis development by promoting the osteogenic differentiation of bone marrow mesenchymal stem cells.
Polydopamine-functionalized acellular fish scale scaffolds for accelerated bone tissue regeneration.
USP22/BRD4 mediated hedgehog pathway activation contributes to airway remodeling in asthma.
Estrogen Inhibits the Phenotypic Switching of Vascular Smooth Muscle Cells through ER-α/CREB in Aortic Dissection.
LncRNA NEAT1 sponges miR-214-3p to promote osteoblast differentiation through regulating the PI3K/AKT/mTOR pathway in aortic valve calcification.
Facile Nanocomposite Hydrogel Scaffold with Sustained Drug Release and Osteo-Immunomodulatory Effects to Enhance Bone Regeneration.
MIR155HG suppresses the osteogenic differentiation of bone marrow mesenchymal stem cells through regulating miR-155-5p and DKK1 expression.
The sonic hedgehog signaling inhibitor cyclopamine improves pulmonary arterial hypertension via regulating the bone morphogenetic protein receptor 2 pathway.
Extracellular Vesicles Derived from H(2)O(2)-Stimulated Adipose-Derived Stem Cells Alleviate Senescence in Diabetic Bone Marrow Mesenchymal Stem Cells and Restore Their Osteogenic Capacity.
Transcriptomic Insights into Hub Genes, Immune Infiltration, and Candidate Drugs in Erosive Esophagitis.
Multifunctional injectable hydrogel system as a mild photothermal-assisted therapeutic platform for programmed regulation of inflammation and osteo-microenvironment for enhanced healing of diabetic bone defects in situ.
Multifunctionally disordered TiO(2) nanoneedles prevent periprosthetic infection and enhance osteointegration by killing bacteria and modulating the osteoimmune microenvironment.
Integrated analysis of colorectal cancer metastasis identifies characteristics of tumor cell during metastasis.
A submicron forest-like silicon surface promotes bone regeneration by regulating macrophage polarization.
GSDMB involvement in the pathogenesis of abdominal aortic aneurysm through regulation of macrophage non-canonical pyroptosis.
Endogenous hydrogen sulfide accelerated trauma-induced heterotopic ossification through the Ca(2+)/ERK pathway-enhanced aberrant osteogenic activity.
KIAA0753 enhances osteoblast differentiation suppressed by diabetes.
Thirdhand smoke exposure promotes gastric tumor development in mouse and human.
Osteoclast-derived exosomes influence osteoblast differentiation in osteoporosis progression via the lncRNA AW011738/ miR-24-2-5p/ TREM1 axis.
Metabolic Control During Macrophage Polarization by a Citrate-Functionalized Scaffold for Maintaining Bone Homeostasis.
Osteopontin deficiency promotes cartilaginous endplate degeneration by enhancing the NF-κB signaling to recruit macrophages and activate the NLRP3 inflammasome.
The Involvement of Endoplasmic Reticulum Stress during the Interaction between Calcium Oxalate Crystals and Renal Tubular Epithelial Cells.
Nitrogen-containing bisphosphonate induces enhancement of OPG expression and inhibition of RANKL expression via inhibition of farnesyl pyrophosphate synthase to inhibit the osteogenic differentiation and calcification in vascular smooth muscle cells.
TRIM16 mitigates impaired osteogenic differentiation and antioxidant response in D-galactose-induced senescent osteoblasts.
SPP1 promotes the polarization of M2 macrophages through the Jak2/Stat3 signaling pathway and accelerates the progression of idiopathic pulmonary fibrosis.
Renal denervation alleviates vascular remodeling in spontaneously hypertensive rats by regulating perivascular adipose tissue.
The resistance to anoikis, mediated by Spp1, and the evasion of immune surveillance facilitate the invasion and metastasis of hepatocellular carcinoma.
LTF ameliorates cartilage endplate degeneration by suppressing calcification, senescence and matrix degradation through the JAK2/STAT3 pathway.
Multifunctional human serum albumin-crosslinked and self-assembling nanoparticles for therapy of periodontitis by anti-oxidation, anti-inflammation and osteogenesis.
Construction of competitive endogenous RNA network and identification of potential regulatory axis in vascular calcification.
Deletion of Kcnj16 altered transcriptomic and metabolomic profiles of Dahl salt-sensitive rats.
From ROS scavenging to boosted osseointegration: cerium-containing mesoporous bioactive glass nanoparticles functionalized implants in diabetes.
Single-cell spatiotemporal analysis of the lungs reveals Slamf9(+) macrophages involved in viral clearance and inflammation resolution.
CD8+ T cell associated scoring model helps prognostic diagnosis and immunotherapy selection in patients with colon adenocarcinoma.
The Altered Proteomic Landscape in Renal Tubular Epithelial Cells under High Oxalate Stimulation.
Early growth response 1 exacerbates thoracic aortic aneurysm and dissection of mice by inducing the phenotypic switching of vascular smooth muscle cell through the activation of Krüppel-like factor 5.
The pivotal role of osteopontin in UV-induced skin inflammation in a mouse model.
Single-cell RNA sequencing reveals immune microenvironment niche transitions during the invasive and metastatic processes of ground-glass nodules and part-solid nodules in lung adenocarcinoma.
HIF-1α knockdown attenuates phenotypic transformation and oxidative stress induced by high salt in human aortic vascular smooth muscle cells.
One-Step Gas Foaming Strategy for Constructing Strontium Nanoparticle Decorated 3D Scaffolds: a New Platform for Repairing Critical Bone Defects.
Bioactive peptide relieves glucocorticoid-induced osteoporosis by giant macrocyclic encapsulation.
Urchin-like multiscale structured fluorinated hydroxyapatite as versatile filler for caries restoration dental resin composites.
CNPY2 governs PDGF‑BB‑treated vascular smooth muscle cell proliferation, migration and phenotypic transformation via the Akt/mTOR/GSK‑3β signaling pathway.
Asprosin aggravates atherosclerosis via regulating the phenotype transformation of vascular smooth muscle cells.
Multifunctional tannic acid-based nanocomposite methacrylated silk fibroin hydrogel with the ability to scavenge reactive oxygen species and reduce inflammation for bone regeneration.
Injectable, anti-collapse, adhesive, plastic and bioactive bone graft substitute promotes bone regeneration by moderating oxidative stress in osteoporotic bone defect.
An integrated multi-omics analysis reveals osteokines involved in global regulation.
Fibrous periosteum repairs bone fracture and maintains the healed bone throughout mouse adulthood.
Activation of CaMKII/HDAC4 by SDF1 contributes to pulmonary arterial hypertension via stabilization Runx2.
Carbonylation of Runx2 at K176 by 4-Hydroxynonenal Accelerates Vascular Calcification.
Spatiotemporal ATF3 Expression Determines VSMC Fate in Abdominal Aortic Aneurysm.
CRYAB suppresses ferroptosis and promotes osteogenic differentiation of human bone marrow stem cells via binding and stabilizing FTH1.
Targeting osteopontin alleviates endometriosis and inflammation by inhibiting the RhoA/ROS axis and achieves non-invasive in vitro detection via menstrual blood.
Osteopontin-driven partial epithelial-mesenchymal transition governs the development of middle ear cholesteatoma.
Murine double minute 2-mediated estrogen receptor 1 degradation activates macrophage migration inhibitory factor to promote vascular smooth muscle cell dedifferentiation and oxidative stress during thoracic aortic aneurysm progression.
Identification of SLC2A1 as a predictive biomarker for survival and response to immunotherapy in lung squamous cell carcinoma.
Mechanism of Porphyra Yezoensis Polysaccharides in Inhibiting Hyperoxalate-Induced Renal Injury and Crystal Deposition.
Hypermethylation of Bmp2 and Fgfr2 Promoter Regions in Bone Marrow Mesenchymal Stem Cells Leads to Bone Loss in Prematurely Aged Mice.
Single-cell RNA sequencing reveals epithelial cells driving brain metastasis in lung adenocarcinoma.
Resolvin D1 attenuates Ang II-induced hypertension in mice by inhibiting the proliferation, migration and phenotypic transformation of vascular smooth muscle cells by blocking the RhoA/mitogen-activated protein kinase pathway.
HOXB9 promotes osteosarcoma cell survival and malignancy under glucose starvation via upregulating SPP1 expression.
Integrated bioinformatics analysis identified leucine rich repeat containing 15 and secreted phosphoprotein 1 as hub genes for calcific aortic valve disease and osteoarthritis.
Targeting deubiquitinase OTUB1 protects vascular smooth muscle cells in atherosclerosis by modulating PDGFRβ.
Elevated SLC1A5 associated with poor prognosis and therapeutic resistance to transarterial chemoembolization in hepatocellular carcinoma.
Iron deficiency affects oxygen transport and activates HIF1 signaling pathway to regulate phenotypic transformation of VSMC in aortic dissection.
CircFgfr2 promotes osteogenic differentiation of rat dental follicle cells by targeting the miR-133a-3p/DLX3 signaling pathway.
The nano-artificial periosteum made of PCL/MgO/AS-IV enhances MC3T3-E1 cell osteogenic differentiation and promotes bone defect repair via the EphB4/EphrinB2 signaling pathway.
An Immunohistochemical Analysis of Osteopontin and S100 Calcium-binding Protein P is Useful for Subclassifying Large- and Small-duct Type Intrahepatic Cholangiocarcinomas.
FOXO1 regulates RUNX2 ubiquitination through SMURF2 in calcific aortic valve disease.
Alginate-containing 3D-printed hydrogel scaffolds incorporated with strontium promotes vascularization and bone regeneration.
NOX4 and its association with myeloperoxidase and osteopontin in regulating endochondral ossification.
SPP1 could be an immunological and prognostic biomarker: From pan-cancer comprehensive analysis to osteosarcoma validation.
Silencing SPP1 in M2 macrophages inhibits the progression of castration-resistant prostate cancer via the MMP9/TGFβ1 axis.
A nanozyme-functionalized bilayer hydrogel scaffold for modulating the inflammatory microenvironment to promote osteochondral regeneration.
Endothelial progenitor cells control remodeling of uterine spiral arteries for the establishment of utero-placental circulation.
Single-cell transcriptomic insights into chemotherapy-induced remodeling of the osteosarcoma tumor microenvironment.
CircTOP1 targeted regulation of PTBP1 expression promotes the progression of coronary artery calcification.
Single-Cell RNA Transcriptome of the Human Endometrium Reveals Epithelial Characterizations Associated with Recurrent Implantation Failure.
KLF2/PPARγ axis contributes to trauma-induced heterotopic ossification by regulating mitochondrial dysfunction.
Myeloid-derived growth factor suppresses VSMC dedifferentiation and attenuates postinjury neointimal formation in rats by activating S1PR2 and its downstream signaling.
Isoliquiritin treatment of osteoporosis by promoting osteogenic differentiation and autophagy of bone marrow mesenchymal stem cells.
3D-printed tri-element-doped hydroxyapatite/ polycaprolactone composite scaffolds with antibacterial potential for osteosarcoma therapy and bone regeneration.
Carp scales derived double cross-linking hydrogels achieve collagen peptides sustained-released for bone regeneration.
A novel lncRNA GM15416 regulates osteoblast apoptosis and differentiation through the c-Fos/Fas axis and mitigates osteoporosis.
AT1R autoantibody promotes phenotypic transition of smooth muscle cells by activating AT1R-OAS2.
S-adenosylmethionine attenuates angiotensin II-induced aortic dissection formation by inhibiting vascular smooth muscle cell phenotypic switch and autophagy.
Regulation of the immune microenvironment by pioglitazone-loaded polylactic glycolic acid nanosphere composite scaffolds to promote vascularization and bone regeneration.
Nanoscaled Titanium Oxide Layer Provokes Quick Osseointegration on 3D-Printed Dental Implants: A Domino Effect Induced by Hydrophilic Surface.
Single-cell profiling of the microenvironment in human bone metastatic renal cell carcinoma.
PRMT3 methylates HIF-1α to enhance the vascular calcification induced by chronic kidney disease.
Alamandine attenuates ovariectomy-induced osteoporosis by promoting osteogenic differentiation via AMPK/eNOS axis.
Nerve growth factor promote osteogenic differentiation of dental pulp stem cells through MEK/ERK signalling pathways.
Biomimetic cryogel promotes the repair of osteoporotic bone defects through altering the ROS niche via down-regulating the ROMO1.
A multifunctional quercetin/polycaprolactone electrospun fibrous membrane for periodontal bone regeneration.
Coenzyme Q10 Protects Against Hyperlipidemia-Induced Osteoporosis by Improving Mitochondrial Function via Modulating miR-130b-3p/PGC-1α Pathway.
Three Birds, One Stone: An Osteo-Microenvironment Stage-Regulative Scaffold for Bone Defect Repair through Modulating Early Osteo-Immunomodulation, Middle Neovascularization, and Later Osteogenesis.
UPP1 promotes lung adenocarcinoma progression through the induction of an immunosuppressive microenvironment.
HDAC2 counteracts vascular calcification by activating autophagy in chronic kidney disease.
Retrospective identification of cell-intrinsic factors that mark pluripotency potential in rare somatic cells.
PMAIP1, a novel diagnostic and potential therapeutic biomarker in osteoporosis.
Dual effect of vitamin D(3) on breast cancer-associated fibroblasts.
Calcitriol promotes M2 polarization of tumor-associated macrophages in 4T1 mouse mammary gland cancer via the induction of proinflammatory cytokines.
CRP inhibits the osteoblastic differentiation of OPCs via the up-regulation of primary cilia and repression of the Hedgehog signaling pathway.
Self-Healing Micro Arc Oxidation and Dicalcium Phosphate Dihydrate Double-Passivated Coating on Magnesium Membrane for Enhanced Bone Integration Repair.
NIR Laser Irradiation Promotes Osteogenic Differentiation of PDLSCs Through the Activation of TRPV1 Channels and Subsequent Calcium Signaling.
Integrated-omics profiling unveils the disparities of host defense to ECM scaffolds during wound healing in aged individuals.
LPS‑mediated adaptation accelerates ecto‑MSCs differentiation into osteoblasts.
Osteoinductivity enhancement by tailoring the surface chemical bond status: A strategy to mobilize host bone growth factors for in situ bone regeneration.
Injectable hyaluronate-based hydrogel with a dynamic/covalent dual-crosslinked architecture for bone tissue engineering: Enhancing osteogenesis and immune regulation.
Modified Titanium Implants Satisfy the Demands of Diabetic Osseointegration via Sequential Regulation of Macrophages and Mesenchymal Stem Cells.
Magnesium-Based Composite Calcium Phosphate Cement Promotes Osteogenesis and Angiogenesis for Minipig Vertebral Defect Regeneration.
A 0.2 T-0.4 T Static Magnetic Field Improves the Bone Quality of Mice Subjected to Hindlimb Unloading and Reloading Through the Dual Regulation of BMSCs via Iron Metabolism.
Single-cell RNA sequencing identifies the expression of hemoglobin in chondrocyte cell subpopulations in osteoarthritis.
Single-cell view and a novel protective macrophage subset in perivascular adipose tissue in T2DM.
Expression of Lumican and Osteopontin in Perivascular Areas of the Glioblastoma Peritumoral Niche and Its Value for Prognosis.
Icariin suppresses osteogenic differentiation and promotes bone regeneration in Porphyromonas gingivalis-infected conditions through EphA2-RhoA signaling pathway.
Single-cell dissection of multifocal bladder cancer reveals malignant and immune cells variation between primary and recurrent tumor lesions.
Dihydromyricetin-loaded oxidized polysaccharide/L-arginine chitosan adhesive hydrogel promotes bone regeneration by regulating PI3K/AKT signaling pathway and MAPK signaling pathway.
Magnetically Induced Anisotropic Microstructures on Polyethylene Glycol Hydrogel Facilitate BMSC Alignment and Osteogenic Differentiation.
Vaspin facilitates the proliferation and osteogenic differentiation of periodontal ligament stem cells.
Tracing Immunological Interaction in Trimethylamine N-Oxide Hydrogel-Derived Zwitterionic Microenvironment During Promoted Diabetic Wound Regeneration.
Fluoride-induced hypertension by regulating RhoA/ROCK pathway and phenotypic transformation of vascular smooth muscle cells: In vitro and in vivo evidence.
Crebanine mitigates glucocorticoid-induced osteonecrosis of the femoral head by restoring bone remodelling homeostasis via attenuating oxidative stress.
miR-200a-3p-enriched MSC-derived extracellular vesicles reverse erectile function in diabetic rats by targeting Keap1.
Titanium nanoparticles released from orthopedic implants induce muscle fibrosis via activation of SNAI2.
BRF1 promotes the odontogenic differentiation of dental pulp stem cells in pulpitis by inducing autophagy.
PTPN14 aggravates neointimal hyperplasia via boosting PDGFRβ signaling in smooth muscle cells.
Identification of diagnostic biomarkers and immune cell infiltration in tongue squamous cell carcinoma using bioinformatic approaches.
Toll-like receptor 4 deficiency affects the balance of osteoclastogenesis and osteoblastogenesis in periodontitis.
M2 Macrophage-Derived Exosomes Inhibit Atherosclerosis Progression by Regulating the Proliferation, Migration, and Phenotypic Transformation of Smooth Muscle Cells.
Integrative analysis unveils ECM signatures and pathways driving hepatocellular carcinoma progression: A multi-omics approach and prognostic model development.
Phytic acid promotes high glucose-mediated bone marrow mesenchymal stem cells osteogenesis via modulating circEIF4B that sponges miR-186-5p and complexes with IGF2BP3.
CGRP attenuates pulmonary vascular remodeling by inhibiting the cGAS-STING-NFκB pathway in pulmonary arterial hypertension.
Complex intrinsic abnormalities in osteoblast lineage cells of X-linked hypophosphatemia: Analysis of human iPS cell models generated by CRISPR/Cas9-mediated gene ablation.
Improving osseointegration and antimicrobial properties of titanium implants with black phosphorus nanosheets-hydroxyapatite composite coatings for vascularized bone regeneration.
Suramin inhibits phenotypic transformation of vascular smooth muscle cells and neointima hyperplasia by suppressing transforming growth factor beta receptor 1 /Smad2/3 pathway activation.
Single-Cell Transcriptional Profile Construction of Rat Pituitary Glands before and after Sexual Maturation and Identification of Novel Marker Spp1 in Gonadotropes.
Chromosomal 3q amplicon encodes essential regulators of secretory vesicles that drive secretory addiction in cancer.
Trimethylamine N-oxide Promotes Atherosclerosis by Regulating Low-Density Lipoprotein-Induced Autophagy in Vascular Smooth Muscle Cells Through PI3K/AKT/mTOR Pathway.
miR-145 Alleviates Smooth Muscle Cell Phenotype Transition via ADAM17-Mediated ACE2 Shedding.
Protective Effect of Alkaline Mineral Water on Calcium Oxalate-Induced Kidney Injury in Mice.
Therapeutic Effects of Mechanical Stress-Induced C2C12-Derived Exosomes on Glucocorticoid-Induced Osteoporosis Through miR-92a-3p/PTEN/AKT Signaling Pathway.
High-fat diet causes undesirable bone regeneration by altering the bone marrow environment in rats.
Ectomesenchymal Six1 controls mandibular skeleton formation.
S-propargyl-cysteine promotes the stability of atherosclerotic plaque via maintaining vascular muscle contractile phenotype.
Sustained delivery of osteogenic growth peptide through injectable photoinitiated composite hydrogel for osteogenesis.
Mir-142-5p inhibits the osteogenic differentiation of bone marrow mesenchymal stem cells by targeting Lhx8.
The response and resistance to drugs in ovarian cancer cell lines in 2D monolayers and 3D spheroids.
Effect of sulfonation time on physicochemical, osteogenic, antibacterial properties and biocompatibility of carbon fiber reinforced polyether ether ketone.
Milk-Derived Small Extracellular Vesicles Promote Osteogenic Differentiation and Inhibit Inflammation via microRNA-21.
Single-cell epigenome analysis identifies molecular events controlling direct conversion of human fibroblasts to pancreatic ductal-like cells.
A composite membrane with microtopographical morphology to regulate cellular behavior for improved tissue regeneration.
Inhibition of AT1R/IP3/IP3R-mediated Ca(2+) release protects against calcium oxalate crystals-induced renal oxidative stress.
A nano-conductive osteogenic hydrogel to locally promote calcium influx for electro-inspired bone defect regeneration.
lncRNA MEG3 Promotes Osteogenic Differentiation of Tendon Stem Cells Via the miR-129-5p/TCF4/β-Catenin Axis and thus Contributes to Trauma-Induced Heterotopic Ossification.
Ganoderma lucidum polysaccharide peptide (GLPP) attenuates rheumatic arthritis in rats through inactivating NF-κB and MAPK signaling pathways.
Sodium-glucose cotransporter 2 inhibitor canagliflozin alleviates vascular calcification through suppression of nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing-3 inflammasome.
The Wnt/β-catenin signaling pathway inhibits osteoporosis by regulating the expression of TERT: an in vivo and in vitro study.
Knockdown of Bach1 protects periodontal bone regeneration from inflammatory damage.
Impaired Growth Plate Maturation in XLH Is due to Both Excess FGF23 and Decreased 1,25-Dihydroxyvitamin D Signaling.
Melatonin-Primed Mesenchymal Stem Cells-Derived Small Extracellular Vesicles Alleviated Neurogenic Erectile Dysfunction by Reversing Phenotypic Modulation.
Apatinib remodels the immunosuppressive tumor ecosystem of gastric cancer enhancing anti-PD-1 immunotherapy.
Apolipoprotein E facilitates titanium implant osseointegration by regulating osteogenesis-lipogenesis balance.
Realizing Highly Efficient Sonodynamic Bactericidal Capability through the Phonon-Electron Coupling Effect Using Two-Dimensional Catalytic Planar Defects.
Mechanistic Insights into the Role of OPN in Mediating Brain Damage via Triggering Lysosomal Damage in Microglia/Macrophage.
Bioinspired Piezoelectric Periosteum to Augment Bone Regeneration via Synergistic Immunomodulation and Osteogenesis.
IL-1β contributes to the secretion of sclerostin by osteocytes and targeting sclerostin promotes spinal fusion at early stages.
FAM3A mediates the phenotypic switch of human aortic smooth muscle cells stimulated with oxidised low-density lipoprotein by influencing the PI3K-AKT pathway.
Bone microenvironment regulative hydrogels with ROS scavenging and prolonged oxygen-generating for enhancing bone repair.
Continuously released Zn(2+) in 3D-printed PLGA/β-TCP/Zn scaffolds for bone defect repair by improving osteoinductive and anti-inflammatory properties.
The marriage of immunomodulatory, angiogenic, and osteogenic capabilities in a piezoelectric hydrogel tissue engineering scaffold for military medicine.
Clock genes are expressed in cementum and regulate the proliferation and mineralization of cementoblasts.
Circular RNA CircSLC8A1 contributes to osteogenic differentiation in hBMSCs via CircSLC8A1/miR-144-3p/RUNX1 in periprosthetic osteolysis.
Single-cell RNA sequencing analysis revealed cellular and molecular immune profiles in lung squamous cell carcinoma.
A TEMPOL and rapamycin loaded nanofiber-covered stent favors endothelialization and mitigates neointimal hyperplasia and local inflammation.
Reversing the imbalance in bone homeostasis via sustained release of SIRT-1 agonist to promote bone healing under osteoporotic condition.
Calcium Phosphate Bone Cements Incorporated with Black Phosphorus Nanosheets Enhanced Osteogenesis.
Cannabidiol Rescues TNF-α-Inhibited Proliferation, Migration, and Osteogenic/Odontogenic Differentiation of Dental Pulp Stem Cells.
PKR deficiency delays vascular aging via inhibiting GSDMD-mediated endothelial cell hyperactivation.
Bta-miR-200b promotes endometrial epithelial cell apoptosis by targeting MYB in cattle.
Type 1 diabetes mellitus leads to gingivitis and an early compensatory increase in bone remodeling.
Metformin enhances the osteogenic activity of rat bone marrow mesenchymal stem cells by inhibiting oxidative stress induced by diabetes mellitus: an in vitro and in vivo study.
Ferroptotic stress facilitates smooth muscle cell dedifferentiation in arterial remodelling by disrupting mitochondrial homeostasis.
Macrophage migration inhibitory factor (MIF) inhibitor iSO-1 promotes staphylococcal protein A-induced osteogenic differentiation by inhibiting NF-κB signaling pathway.
Stimulus-Responsive Zwitterionic Prodrug Delivery System with Sustained Release of Hydrogen Sulfide for Protective Aortic Dissection.
Influence of FOSL1 Inhibition on Vascular Calcification and ROS Generation through Ferroptosis via P53-SLC7A11 Axis.
Retrospective identification of intrinsic factors that mark pluripotency potential in rare somatic cells.
Hypoxia Inhibits Cell Cycle Progression and Cell Proliferation in Brain Microvascular Endothelial Cells via the miR-212-3p/MCM2 Axis.
Co-overexpression of OPN, IGF-1 and CNTF augment the therapeutic effect of DPSC on spinal cord injury.
Engineered muscle from micro-channeled PEG scaffold with magnetic Fe(3)O(4) fixation towards accelerating esophageal muscle repair.
Overexpression of LOX-1 in hepatocytes protects vascular smooth muscle cells from phenotype transformation and wire injury induced carotid neoatherosclerosis through ALOX15.
CDN1163 alleviates SERCA2 dysfunction-induced pulmonary vascular remodeling by inhibiting the phenotypic transition of pulmonary artery smooth muscle cells.
Non-canonical function of histone methyltransferase G9a in the translational regulation of chronic inflammation.
The LRP5 high-bone-mass mutation causes alveolar bone accrual with minor craniofacial alteration.
Transcription factor 21 accelerates vascular calcification in mice by activating the IL-6/STAT3 signaling pathway and the interplay between VSMCs and ECs.
A Recombinant Parathyroid Hormone-Related Peptide Locally Applied in Osteoporotic Bone Defect.
miR-342-5p promotes vascular smooth muscle cell phenotypic transition through a negative-feedback regulation of Notch signaling via targeting FOXO3.
Changes in N6-methyladenosine RNA methylomes of human periodontal ligament cells in response to inflammatory conditions.
Nitration of cAMP-Response Element Binding Protein Participates in Myocardial Infarction-Induced Myocardial Fibrosis via Accelerating Transcription of Col1a2 and Cxcl12.
Identification of hub genes and pathways in lung metastatic colorectal cancer.
EMT-activated secretory and endocytic vesicular trafficking programs underlie a vulnerability to PI4K2A antagonism in lung cancer.
Osteopontin Promotes Macrophage M1 Polarization by Activation of the JAK1/STAT1/HMGB1 Signaling Pathway in Nonalcoholic Fatty Liver Disease.
Synergistic Effect of Magneto-Mechanical Bioengineered Stem Cells and Magnetic Field to Alleviate Osteoporosis.
BRG1 is involved in vascular calcification in chronic renal disease via autophagy of vascular smooth muscle cells.
Potential of an Aligned Porous Hydrogel Scaffold Combined with Periodontal Ligament Stem Cells or Gingival Mesenchymal Stem Cells to Promote Tissue Regeneration in Rat Periodontal Defects.
Biophysical Analysis and Preclinical Pharmacokinetics-Pharmacodynamics of Tangential Flow Filtration Fractionated Polymerized Human Hemoglobin as a Red Blood Cell Substitute.
Shared gene characteristics and molecular mechanisms of macrophages M1 polarization in calcified aortic valve disease.
Hsa_circRNA_0008028 Deficiency Ameliorates High Glucose-Induced Proliferation, Calcification, and Autophagy of Vascular Smooth Muscle Cells via miR-182-5p/TRIB3 Axis.
Preparation and Biocompatibility of Core-Shell Microspheres for Sequential, Sustained Release of BMP-2 and VEGF.
OPN Promotes Cell Proliferation and Invasion through NF-κB in Human Esophageal Squamous Cell Carcinoma.
Assessing serum levels of SM22α as a new biomarker for patients with aortic aneurysm/dissection.
Akkermansia muciniphila Alters Gut Microbiota and Immune System to Improve Cardiovascular Diseases in Murine Model.
Pan-Cancer Analysis of the Immunological Role of PDIA5: A Potential Target for Immunotherapy.
Hypoxia During the Consolidation Phase of Distraction Osteogenesis Promotes Bone Regeneration.
Pan-Cancer Analysis Reveals a Distinct Neutrophil Extracellular Trap-Associated Regulatory Pattern.
CCAAT/Enhancer-Binding Protein Alpha Is a Novel Regulator of Vascular Smooth Muscle Cell Osteochondrogenic Transition and Vascular Calcification.
TSH-SPP1/TRβ-TSH positive feedback loop mediates fat deposition of hepatocyte: Crosstalk between thyroid and liver.
Dissecting a hypoxia-related angiogenic gene signature for predicting prognosis and immune status in hepatocellular carcinoma.
Potassium Titanate Assembled Titanium Dioxide Nanotube Arrays Endow Titanium Implants Excellent Osseointegration Performance and Nerve Formation Potential.
Construction and osteogenic effects of 3D-printed porous titanium alloy loaded with VEGF/BMP-2 shell-core microspheres in a sustained-release system.
NRF2 is a critical regulator and therapeutic target of metal implant particle-incurred bone damage.
Negative pressure wound therapy improves bone regeneration by promoting osteogenic differentiation via the AMPK-ULK1-autophagy axis.
Dual Biosignal-Functional Injectable Microspheres for Remodeling Osteogenic Microenvironment.
Substitution of SERCA2 Cys(674) accelerates aortic aneurysm by inducing endoplasmic reticulum stress and promoting cell apoptosis.
The Protective Effects on Ischemia-Reperfusion Injury Mechanisms of the Thoracic Aorta in Daurian Ground Squirrels (Spermophilus dauricus) over the Torpor-Arousal Cycle of Hibernation.
Oxalate induces the ossification of RTECs by activating the JAK2/STAT3 signaling pathway and participates in the formation of kidney stones.
Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Enhance the Osteoblastic Differentiation of Periodontal Ligament Stem Cells Under High Glucose Conditions Through the PI3K/AKT Signaling Pathway.
Impact of Resolvin D1 on the inflammatory phenotype of periodontal ligament cell response to hypoxia.
LncRNA LINC00281/Annexin A2 Regulates Vascular Smooth Muscle Cell Phenotype Switching via the Nuclear Factor-Kappa B Signaling Pathway.
Gut microbiome dysbiosis contributes to abdominal aortic aneurysm by promoting neutrophil extracellular trap formation.
Iron overload-induced ferroptosis of osteoblasts inhibits osteogenesis and promotes osteoporosis: An in vitro and in vivo study.
Identification of osteopontin as a urinary biomarker for autosomal dominant polycystic kidney disease progression.
Fecal microbiota transplantation ameliorates bone loss in mice with ovariectomy-induced osteoporosis via modulating gut microbiota and metabolic function.
Niobium promotes fracture healing in rats by regulating the PI3K-Akt signalling pathway: An in vivo and in vitro study.
MiR-145 inhibits the differentiation and proliferation of bone marrow stromal mesenchymal stem cells by GABARAPL1 in steroid-induced femoral head necrosis.
CircZXDC Promotes Vascular Smooth Muscle Cell Transdifferentiation via Regulating miRNA-125a-3p/ABCC6 in Moyamoya Disease.
Decorin Promotes Osteoblastic Differentiation of Human Periodontal Ligament Stem Cells.
Salidroside protects against osteoporosis in ovariectomized rats by inhibiting oxidative stress and promoting osteogenesis via Nrf2 activation.
Carboxymethyl chitin or chitosan for osteoinduction effect on the human periodontal ligament stem cells.
Intraoperative Hypothermia Induces Vascular Dysfunction in the CA1 Region of Rat Hippocampus.
Mussel-inspired multifunctional surface through promoting osteogenesis and inhibiting osteoclastogenesis to facilitate bone regeneration.
STARD3NL inhibits the osteogenic differentiation by inactivating the Wnt/β-catenin pathway via binding to Annexin A2 in osteoporosis.
Molecular feature of arterial remodeling in the brain arteriovenous malformation revealed by arteriovenous shunt rat model and RNA sequencing.
MicroRNA-27a-3p inhibits lung and skin fibrosis of systemic sclerosis by negatively regulating SPP1.
Iron deficiency exacerbates aortic medial degeneration by inducing excessive mitochondrial fission.
Semaphorin3A promotes osseointegration of titanium implants in osteoporotic rabbits.
Increased expression of osteopontin in subchondral bone promotes bone turnover and remodeling, and accelerates the progression of OA in a mouse model.
SIRT6 protects vascular smooth muscle cells from osteogenic transdifferentiation via Runx2 in chronic kidney disease.
Development of Intracorporeal Differentiation of Stem Cells to Induce One-Step Mastoid Bone Reconstruction during Otitis Media Surgeries.
Osteopontin expression in the invasive front stroma of colorectal adenocarcinoma is associated with tumor budding and prognosis.
Dickkopf1 (Dkk1) Alleviates Vascular Calcification by Regulating the Degradation of Phospholipase D1 (PLD1).
Halide-containing bioactive glasses enhance osteogenesis in vitro and in vivo.
PVT1/miR-145-5p/HK2 modulates vascular smooth muscle cells phenotype switch via glycolysis: The new perspective on the spiral artery remodeling.
Mesoporous Silica Promotes Osteogenesis of Human Adipose-Derived Stem Cells Identified by a High-Throughput Microfluidic Chip Assay.
Electroactive Hydroxyapatite/Carbon Nanofiber Scaffolds for Osteogenic Differentiation of Human Adipose-Derived Stem Cells.
Multi-Transcriptomic Analysis Reveals the Heterogeneity and Tumor-Promoting Role of SPP1/CD44-Mediated Intratumoral Crosstalk in Gastric Cancer.
Icariin Treatment Rescues Diabetes Induced Bone Loss via Scavenging ROS and Activating Primary Cilia/Gli2/Osteocalcin Signaling Pathway.
Circular RNA BIRC6 depletion promotes osteogenic differentiation of periodontal ligament stem cells via the miR-543/PTEN/PI3K/AKT/mTOR signaling pathway in the inflammatory microenvironment.
The Annexin A2-Notch regulatory loop in hepatocytes promotes liver fibrosis in NAFLD by increasing osteopontin expression.
Cinnamaldehyde protects against ligature-induced periodontitis through the inhibition of microbial accumulation and inflammatory responses of host immune cells.
Immunohistochemical expression of osteopontin and collagens in choroid plexus of human brains.
N-acetylcysteine promotes cyclic mechanical stress-induced osteogenic differentiation of periodontal ligament stem cells by down-regulating Nrf2 expression.
Bmal1 promotes cementoblast differentiation and cementum mineralization via Wnt/β-catenin signaling.
Decoding the temporal and regional specification of microglia in the developing human brain.
ELAV-like RNA binding protein 1 regulates osteogenesis in diabetic osteoporosis: Involvement of divalent metal transporter 1.
Role of (pro)renin receptor in cyclosporin A-induced nephropathy.
Bioinformatics analysis of laryngeal squamous cell carcinoma: seeking key candidate genes and pathways.
Nrf2 Activation Is Involved in Cyclic Mechanical Stress-Stimulated Osteogenic Differentiation in Periodontal Ligament Stem Cells via PI3K/Akt Signaling and HO1-SOD2 Interaction.
Cyclic Distraction-Compression Dynamization Technique Enhances the Bone Formation During Distraction Osteogenesis.
Long Non-coding RNAs LOC100126784 and POM121L9P Derived From Bone Marrow Mesenchymal Stem Cells Enhance Osteogenic Differentiation via the miR-503-5p/SORBS1 Axis.
FBS-Derived Exosomes as a Natural Nano-Scale Carrier for Icariin Promote Osteoblast Proliferation.
PRDX2 Protects Against Atherosclerosis by Regulating the Phenotype and Function of the Vascular Smooth Muscle Cell.
Metformin Inhibits Abdominal Aortic Aneurysm Formation through the Activation of the AMPK/mTOR Signaling Pathway.
The effects of PIKfyve inhibitor YM201636 on claudins and malignancy potential of nonsmall cell cancer cells.
Quantitative Proteomics Reveals the Dynamic Pathophysiology Across Different Stages in a Rat Model of Severe Traumatic Brain Injury.
Dura cells in the etiopathogenesis of Crouzon syndrome: the effects of FGFR2 mutations in the dura cells on the proliferation of osteoblasts through the hippo/YAP mediated transcriptional regulation pathway.
Identification and Validation of a Tumor Microenvironment-Related Gene Signature in Hepatocellular Carcinoma Prognosis.
Identification of VWF as a Novel Biomarker in Lung Adenocarcinoma by Comprehensive Analysis.
Exogenous H(2) S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
Biomimetic Cell-Substrate of Chitosan-Cross-linked Polyaniline Patterning on TiO(2) Nanotubes Enables hBM-MSCs to Differentiate the Osteoblast Cell Type.
Polydopamine-Coated Poly(l-lactide) Nanofibers with Controlled Release of VEGF and BMP-2 as a Regenerative Periosteum.
Association of urinary ketamine and APOA1 levels with bladder dysfunction in ketamine abusers revealed via proteomics and targeted metabolite analyses.
ET(A)R silencing ameliorated neurovascular injury after SAH in rats through ERK/KLF4-mediated phenotypic transformation of smooth muscle cells.
Primary cilia regulate gastric cancer-induced bone loss via cilia/Wnt/β-catenin signaling pathway.
Inactivation of SERCA2 Cys(674) accelerates aortic aneurysms by suppressing PPARγ.
Long-lasting renewable antibacterial porous polymeric coatings enable titanium biomaterials to prevent and treat peri-implant infection.
Nrf2 activation is involved in osteogenic differentiation of periodontal ligament stem cells under cyclic mechanical stretch.
The preventive and therapeutic effects of AAV1-KLF4-shRNA in cigarette smoke-induced pulmonary hypertension.
A protumorigenic secretory pathway activated by p53 deficiency in lung adenocarcinoma.
A Dual Role of Heme Oxygenase-1 in Angiotensin II-Induced Abdominal Aortic Aneurysm in the Normolipidemic Mice.
Significance of MR/OPN/HMGB1 axis in NAFLD-associated hepatic fibrogenesis.
lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.
Prostacyclin facilitates vascular smooth muscle cell phenotypic transformation via activating TP receptors when IP receptors are deficient.
MSCs-extracellular vesicles attenuated neuroinflammation, synapse damage and microglial phagocytosis after hypoxia-ischemia injury by preventing osteopontin expression.
MicroRNA-520c-3p targeting of RelA/p65 suppresses atherosclerotic plaque formation.
Polypeptides IGF-1C and P24 synergistically promote osteogenic differentiation of bone marrow mesenchymal stem cells in vitro through the p38 and JNK signaling pathways.
Geniposide Ameliorated Dexamethasone-Induced Cholesterol Accumulation in Osteoblasts by Mediating the GLP-1R/ABCA1 Axis.
Establishment and characterization of a highly metastatic human osteosarcoma cell line from osteosarcoma lung metastases.
Polo Like Kinase 4 (PLK4) impairs human bone marrow mesenchymal stem cell (BMSC) viability and osteogenic differentiation.
Higher BMP Expression in Tendon Stem/Progenitor Cells Contributes to the Increased Heterotopic Ossification in Achilles Tendon With Aging.
Piperlongumine Attenuates High Calcium/Phosphate-Induced Arterial Calcification by Preserving P53/PTEN Signaling.
Ethyl Acetate Fraction from Hedyotis diffusa plus Scutellaria barbata Suppresses Migration of Bone-Metastatic Breast Cancer Cells via OPN-FAK/ERK/NF-κB Axis.
OPN Deficiency Increases the Severity of Osteoarthritis Associated with Aberrant Chondrocyte Senescence and Apoptosis and Upregulates the Expression of Osteoarthritis-Associated Genes.
R-Spondin 2 Induces Odontogenic Differentiation of Dental Pulp Stem/Progenitor Cells via Regulation of Wnt/β-Catenin Signaling.
Ginsenoside Rg3 attenuates ovariectomy-induced osteoporosis via AMPK/mTOR signaling pathway.
RNA-seq analysis of palatal transcriptome changes in all-trans retinoic acid-induced cleft palate of mice.
TL1A inhibits atherosclerosis in apoE-deficient mice by regulating the phenotype of vascular smooth muscle cells.
Novel gene-specific translation mechanism of dysregulated, chronic inflammation reveals promising, multifaceted COVID-19 therapeutics.
T-cell death-associated gene 8 accelerates atherosclerosis by promoting vascular smooth muscle cell proliferation and migration.
Exercise Promotes the Osteoinduction of HA/β-TCP Biomaterials via the Wnt Signaling Pathway.
Cortistatin ameliorates Ang II-induced proliferation of vascular smooth muscle cells by inhibiting autophagy through SSTR3 and SSTR5.
Quantitative alterations in bovine milk proteome from healthy, subclinical and clinical mastitis during S. aureus infection.
Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function.
The effect of extracellular matrix on the differentiation of mouse embryonic stem cells.
SHED-derived conditioned exosomes enhance the osteogenic differentiation of PDLSCs via Wnt and BMP signaling in vitro.
Activation of cannabinoid receptor type 2-induced osteogenic differentiation involves autophagy induction and p62-mediated Nrf2 deactivation.
Modulation of the mechanosensing of mesenchymal stem cells by laser-induced patterning for the acceleration of tissue reconstruction through the Wnt/β-catenin signaling pathway activation.
P38 MAPK signaling pathway mediates COM crystal-induced crystal adhesion change in rat renal tubular epithelial cells.
Semaphorin 3A-hypoxia inducible factor 1 subunit alpha co-overexpression enhances the osteogenic differentiation of induced pluripotent stem cells-derived mesenchymal stem cells in vitro.
PKM2 suppresses osteogenesis and facilitates adipogenesis by regulating β-catenin signaling and mitochondrial fusion and fission.
Sustained delivery of PlGF-2(123-144*)-fused BMP2-related peptide P28 from small intestinal submucosa/polylactic acid scaffold material for bone tissue regeneration.
Daphnetin ameliorates glucocorticoid-induced osteoporosis via activation of Wnt/GSK-3β/β-catenin signaling.
Smooth muscle NADPH oxidase 4 promotes angiotensin II-induced aortic aneurysm and atherosclerosis by regulating osteopontin.
Biomineralizaion of hydroxyapatite on polyethylene terephthalate artificial ligaments promotes graft-bone healing after anterior cruciate ligament reconstruction: An in vitro and in vivo study.
AKT/FOXO1 axis links cross-talking of endothelial cell and pericyte in TIE2-mutated venous malformations.
Effect of interleukin-33 on cementoblast-mediated cementum repair during orthodontic tooth movement.
A novel Sprouty4-ERK1/2-Wnt/β-catenin regulatory loop in marrow stromal progenitor cells controls osteogenic and adipogenic differentiation.
Excessive Methionine Supplementation Exacerbates the Development of Abdominal Aortic Aneurysm in Rats.
Icariin Protects Bone Marrow Mesenchymal Stem Cells Against Iron Overload Induced Dysfunction Through Mitochondrial Fusion and Fission, PI3K/AKT/mTOR and MAPK Pathways.
2,3,7,8-Tetrachlorodibenzo-p-dioxin promotes injury-induced vascular neointima formation in mice.
Inhibiting effect of microRNA-187-3p on osteogenic differentiation of osteoblast precursor cells by suppressing cannabinoid receptor type 2.
[Down-regulation of miR-381-3p inhibits osteogenic differentiation of mouse embryonic palatal mesenchymal cells in 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-induced cleft palate of fetal mice].
Incorporated-bFGF polycaprolactone/polyvinylidene fluoride nanocomposite scaffold promotes human induced pluripotent stem cells osteogenic differentiation.
SPARC induces phenotypic modulation of human brain vascular smooth muscle cells via AMPK/mTOR-mediated autophagy.
Osteopontin in the Pathogenesis of Aortic Dissection by the Enhancement of MMP Expressions.
Citric acid enhances the physical properties, cytocompatibility and osteogenesis of magnesium calcium phosphate cement.
The role and mechanism of transforming growth factor beta 3 in human myocardial infarction-induced myocardial fibrosis.
Small molecule inhibitor of TGF-β signaling enables robust osteogenesis of autologous GMSCs to successfully repair minipig severe maxillofacial bone defects.
Adipose-derived stem cells-conditioned medium improved osteogenic differentiation of induced pluripotent stem cells when grown on polycaprolactone nanofibers.
Peroxisome Proliferator-Activated Receptor-γ Coactivator-1α Inhibits Vascular Calcification Through Sirtuin 3-Mediated Reduction of Mitochondrial Oxidative Stress.
Circulating osteopontin per tumor volume as a prognostic biomarker for resectable intrahepatic cholangiocarcinoma.
Effect of Hydroxyapatite Nanorods on the Fate of Human Adipose-Derived Stem Cells Assessed In Situ at the Single Cell Level with a High-Throughput, Real-Time Microfluidic Chip.
Study of Bone Regeneration and Osteointegration Effect of a Novel Selective Laser-Melted Titanium-Tantalum-Niobium-Zirconium Alloy Scaffold.
Efficient osteogenic differentiation of the dental pulp stem cells on β-glycerophosphate loaded polycaprolactone/polyethylene oxide blend nanofibers.
Quantitative proteomics of milk whey reveals breed and season specific variation in protein abundance in Holstein Friesian cow and Murrah buffalo.
Effect of microRNA-21 on hypoxia-inducible factor-1α in orthodontic tooth movement and human periodontal ligament cells under hypoxia.
Promoting osteogenic differentiation of human-induced pluripotent stem cells by releasing Wnt/β-catenin signaling activator from the nanofibers.
Validation of Phosphodiesterase-10 as a Novel Target for Pulmonary Arterial Hypertension via Highly Selective and Subnanomolar Inhibitors.
New Application of Psoralen and Angelicin on Periodontitis With Anti-bacterial, Anti-inflammatory, and Osteogenesis Effects.
Downregulated Expression of Solute Carrier Family 26 Member 6 in NRK-52E Cells Attenuates Oxalate-Induced Intracellular Oxidative Stress.
Osteopontin is essential for IL-1β production and apoptosis in peri-implantitis.
Hypoxia-Inducible Factor-1α (HIF-1α) Expression on Endothelial Cells in Juvenile Nasopharyngeal Angiofibroma: A Review of 70 cases and Tissue Microarray Analysis.
Nesfatin-1 promotes VSMC migration and neointimal hyperplasia by upregulating matrix metalloproteinases and downregulating PPARγ.
Negative pressure wound therapy promotes muscle-derived stem cell osteogenic differentiation through MAPK pathway.
Teniposide regulates the phenotype switching of vascular smooth muscle cells in a miR-21-dependent manner.
Myricetin ameliorates glucocorticoid-induced osteoporosis through the ERK signaling pathway.
Osteopontin contributes to effective neutrophil recruitment, IL-1β production and apoptosis in Aspergillus fumigatus keratitis.
The prognostic value of osteopontin in limited-stage small cell lung cancer patients and its mechanism.
The protective effect of PFTα on alcohol-induced osteonecrosis of the femoral head.
MgAl layered double hydroxide/chitosan porous scaffolds loaded with PFTα to promote bone regeneration.
SC79-loaded ZSM-5/chitosan porous scaffolds with enhanced stem cell osteogenic differentiation and bone regeneration.
Microarray-based detection and expression analysis of new genes associated with drug resistance in ovarian cancer cell lines.
Transcriptome analysis in primary colorectal cancer tissues from patients with and without liver metastases using next-generation sequencing.
MicroRNA-99a inhibits insulin-induced proliferation, migration, dedifferentiation, and rapamycin resistance of vascular smooth muscle cells by inhibiting insulin-like growth factor-1 receptor and mammalian target of rapamycin.
Interleukin-6 enhances cancer stemness and promotes metastasis of hepatocellular carcinoma via up-regulating osteopontin expression.
Large tumor suppressor homologs 1 and 2 regulate mouse liver progenitor cell proliferation and maturation through antagonism of the coactivators YAP and TAZ.
Intrarenal macrophage infiltration induced by T cells is associated with podocyte injury in lupus nephritis patients.
Comparative investigation of human amniotic epithelial cells and mesenchymal stem cells for application in bone tissue engineering.
The chemokine CXCL13 in lung cancers associated with environmental polycyclic aromatic hydrocarbons pollution.
Serum anti-osteopontin autoantibody as a novel diagnostic and prognostic biomarker in patients with hepatocellular carcinoma.
Protective effects of epigallocatechin gallate (EGCG) on streptozotocin-induced diabetic nephropathy in mice.
Characterization of a micro-roughened TiO2/ZrO2 coating: mechanical properties and HBMSC responses in vitro.
Osteogenic differentiation of human amniotic epithelial cells and its application in alveolar defect restoration.
Deng P, Zheng M, Du B, Liu C, Cheng R, Liu C, Wang F, Dong H, Shan Y, Xu Y
Regenerative biomaterials 2026;13:rbag023
Regenerative biomaterials 2026;13:rbag023
A near-infrared regulated programmable multi-mode periosteum scaffold for sequential healing of infected bone defects.
Yin Y, Cai Y, Dang P, Zeng W, Wang L, Yan X, Luo Z, Liu W, Zhu Y, Chen L, Zhang C
Bioactive materials 2026 Sep;63:56-72
Bioactive materials 2026 Sep;63:56-72
Study on the pro-inflammatory mechanism mediated by the RANK-SPP1 axis in macrophage immunomodulation during atherosclerosis.
Sun Q, Hu Y, Sun Z, Shang M, Li Z, Shen J, Cui Z, Yang J, Ma X, Li M
Molecular and cellular biochemistry 2026 May;481(5):2267-2289
Molecular and cellular biochemistry 2026 May;481(5):2267-2289
Masking macrophage injury sensing via poly I sustained release system reduces inflammation and fibrosis.
Chen K, You X, Yu W, Xu Z, Wang B, Ma J, Zhao X, Zhang W, He S, Gao C, Zhang T, Yuan WE, Hu B, Chen H
Biomaterials 2026 May;328:123865
Biomaterials 2026 May;328:123865
Single-cell and spatial transcriptomics identify PGK1-sensitized hypoxia macrophages as a therapeutic target to overcome PDT resistance in glioma.
Yan X, Hu J, Han X, Xu L, Zhou L, He J, Yang F, Zhou L, Niu Y, Geng M, Yuan W, Zhao D, Du J, Hu S
Journal of photochemistry and photobiology. B, Biology 2026 May;278:113430
Journal of photochemistry and photobiology. B, Biology 2026 May;278:113430
TRAP5 Inhibition Targeting Scar-Associated Macrophages Ameliorates Acute Kidney Injury to Chronic Kidney Disease Transition.
Wang C, Gu Y, Du W, Xie L, Quan J, Zhao Y, Cheng Y, Wei Z, Sha Y, Wang Y, Xu D, Gao X, Chen M, Gu X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(26):e19855
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(26):e19855
Isoliquiritigenin restores bone homeostasis in osteoporotic rats by enhancing BMSCs osteogenesis via ERK1/2-mTOR-HIF-1α-glycolytic axis and suppressing inflammation.
Chang H, Li Y, Wang Z, Fang Z, Chen H, Xu C, Jiao X, Gan Y
International immunopharmacology 2026 May 1;176:116440
International immunopharmacology 2026 May 1;176:116440
Tumor-intrinsic redox programming drives an SPP1-CD44 axis of immune suppression in uveal melanoma.
Ge T, Yang Y, Zhang W, Li M, Gu X, Yang L, Jia R, Wang X, Fan X, Zhuang A
Redox biology 2026 Mar;90:104011
Redox biology 2026 Mar;90:104011
Ciliary IFT88 inhibits intervertebral disc degeneration under excessive mechanical stress by regulating endplate cartilage calcification.
Dong ZR, Wang J, Huang YK, Ding W, He HX, Yuan GC, Gao ZY, Ge YX, Wang WX, Jiang LB, Zhao MD
Journal of advanced research 2026 Mar;81:157-173
Journal of advanced research 2026 Mar;81:157-173
Composite hydrogel-microsphere delivery system promotes early nerve-mediated bone regeneration and late-stage mechanotransduction-driven bone remodeling via sequential release of NGF and Yoda1.
Chen W, Yi Z, Wang X, Wang S, Wang W, Zhang A, Liu F, Shi R, Zheng Y, Liu B
Bioactive materials 2026 Mar;57:531-550
Bioactive materials 2026 Mar;57:531-550
LncRNA GAS5 regulates osteogenic differentiation of human periodontal ligament stem cells through miR-23b-3p/STAT5B axis.
Zhang Q, Huang Y, Huang L, Zhang Z, Zuo Q
Biochemistry and biophysics reports 2026 Mar;45:102516
Biochemistry and biophysics reports 2026 Mar;45:102516
CGRP Enhances the Regeneration of Bone Defects by Regulating Bone Marrow Mesenchymal Stem Cells Through Promoting ANGPTL4 Secretion by Bone Blood Vessels.
Lu Q, Zheng Q, Zhou Z, Chen Y, Chen Y, Chen W, Wang J, Guo R, Wu R, Chen L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(14):e22295
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(14):e22295
NFS1 Regulates IDH2 to Attenuate Abdominal Aortic Aneurysms via Interacting With SP2.
Zhang L, Zhang Y, Wen D, Guo S, Qi X, Wang H, Sun Y, Yang G, Wang Y, Xue S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(14):e05240
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(14):e05240
The TRAF6/SPP1 axis participates in osteoarthritis progression through regulating the catabolism and anabolism of cartilage matrix.
Yao J, Huang J, Li C, Shang J, Lin X, Zhou X, Lu Y
Scientific reports 2026 Mar 4;16(1)
Scientific reports 2026 Mar 4;16(1)
Lung Adenocarcinoma Promotes NETosis via the NPM1-TNFAIP6-CD44-SPP1 Axis.
Liu R, Hu Z, Li M, Yang S, Wang J, Zhang Z, Yang L, Chen J
Cancers 2026 Mar 22;18(6)
Cancers 2026 Mar 22;18(6)
Identification of hub targets involved in carotid atherosclerosis through bioinformatics and machine learning approaches.
Jia L, Bian C, Chen Y, Zhao Y, Yang B, Sun S, Luo T
BMC cardiovascular disorders 2026 Mar 18;26(1)
BMC cardiovascular disorders 2026 Mar 18;26(1)
A Cross-Disease Microglial Transcriptional Program Characterizes Neurodegeneration and Highlights SPP1 as a Biomarker.
Palma A, Stefanelli R, Trenta F, Projetti C, Massa G, Canterini S, Fiorenza MT
Glia 2026 Jun;74(6):e70163
Glia 2026 Jun;74(6):e70163
Geometry-driven immunomodulation in 3D-printed bioceramics: Negative curvature promotes macrophage M2 polarization via Ras-MAPK/HIF-1α signaling for vascularized osteogenesis.
Lu Q, Kuang Y, Diao J, Zheng J, Zhao N, Du C, Wang Y
Bioactive materials 2026 Jun;60:282-298
Bioactive materials 2026 Jun;60:282-298
TGF-β drives pulmonary fibrosis through dual dysregulation of TNF pathway transcription and splicing.
Wang P, Guo M, Zhang Z, Liu G, Liu C, Cai L, Zhao H
European journal of cell biology 2026 Jun;105(2):151534
European journal of cell biology 2026 Jun;105(2):151534
Curcumin modulates the function of SPP1+ macrophages via NF-κB signaling to alleviate endometriosis.
Zong C, Xu J, Jiang Q, Yuan X, Gu R, Chen Y, Zhang B, Yu M, Lin C
International immunopharmacology 2026 Jul 1;180:116644
International immunopharmacology 2026 Jul 1;180:116644
Modular de- and re-construction of vascularized osteochondral tissues in an Organ-on-Chip dual-compartment platform.
Mainardi A, Barbero A, Ehrbar M, Rasponi M, Martin I, Occhetta P
Journal of orthopaedic translation 2026 Jan;56:101017
Journal of orthopaedic translation 2026 Jan;56:101017
Ginsenoside Ro alleviated cuproptosis induced by high oxalate via inhibiting zinc transporter ZnT1 in renal tubular epithelial cells.
Li C, Zhou Y, Nie Y, Fu J, Zeng J, Zhang S, Han L, Li Z, Yang H, Li S, Yu B, Ying X, Wu W
Journal of ginseng research 2026 Jan;50(1):100908
Journal of ginseng research 2026 Jan;50(1):100908
Microenvironment-activatable nanoagent for real-time NIR-II monitoring and targeted therapy of arterial restenosis.
Meng X, Song J, Meng H, Liao C, Yin Z, Gong K, Kong D, Qi J, Duan Y
Biomaterials 2026 Jan;324:123482
Biomaterials 2026 Jan;324:123482
Targeting astrocytic CLC2(CLCN2) restores myelin regeneration through inhibition of SPP1/CD44 signaling pathway in leukoencephalopathy.
Yang L, Lu Y, Liu J, Zhu F, Jiang Y, Lu T, Zhong X, Qiu W, Tang C, Peng F
Molecular psychiatry 2026 Jan;31(1):116-136
Molecular psychiatry 2026 Jan;31(1):116-136
Melatonin promotes osteogenic differentiation of BMSCs by regulating circZFAND1/miR-433-3p/DKK1 pathway through melatonin receptor-dependent m6A modification of circZFAND1.
Shi Y, Yu J, Wu Y, Fang H, Yang B
Bone 2026 Jan;202:117691
Bone 2026 Jan;202:117691
Proteomics analysis of serum extracellular vesicle identifies UCHL1 as a potential therapeutic target for high grade serous ovarian cancer.
Lokman NA, Macpherson AM, Thompson AR, Price ZK, Goonetilleke L, Condina MR, Young C, Hoffmann P, Oehler MK, Ricciardelli C
British journal of cancer 2026 Jan;134(2):195-207
British journal of cancer 2026 Jan;134(2):195-207
Revolutionizing nephrocalcinosis treatment: IL-10 engineered macrophages as a novel therapeutic approach.
Zhao W, Wang K, Chen H, Xu J, Wen L, Wu Y, Chen W, Liu H, Liu Y, Zhang J, Lieske JC, Zhang L, Zhang X, Mai H
Bioengineering & translational medicine 2026 Jan;11(1):e70047
Bioengineering & translational medicine 2026 Jan;11(1):e70047
CA9+ cancer-associated fibroblasts cooperate with SPP1+ tumor-associated macrophages driving immune resistance in triple-negative breast cancer.
Ma Q, Wang J, Jiang Q
Cellular and molecular life sciences : CMLS 2026 Jan 9;83(1):54
Cellular and molecular life sciences : CMLS 2026 Jan 9;83(1):54
Integrated single-cell and bulk RNA sequencing unravels neutrophil heterogeneity and validates SPP1 as a prognostic biomarker in cervical cancer.
Lin S, Zhong J, Yuan S, Su M, Zhang Y, Zhang X
BMC cancer 2026 Jan 30;26(1)
BMC cancer 2026 Jan 30;26(1)
Pathology-tailored nanotherapy via Galectin-3-targeted and triple-responsive nanoparticles enables multimodal therapy against aortic dissection.
Lin C, Tsai ML, Chao HY, Cheng TM, Shih CM, Wu ATH, Cheng CH, Hsiao CY, Lu HY, Shih CC, Mi FL
Journal of nanobiotechnology 2026 Jan 13;24(1):41
Journal of nanobiotechnology 2026 Jan 13;24(1):41
Injectable hydrogels for osteomyelitis treatment induce metabolic reprogramming for protection against reinfection.
Chen H, Wei L, Yu Q, Wang C, Fan H, Li M, Dong R, Ma Y, Jiang J, Deng L, Wu MX, Lu M
Nature communications 2026 Jan 13;17(1):1613
Nature communications 2026 Jan 13;17(1):1613
Pilose antler peptide enhances diabetic fracture healing by modulating the CREB-Smad2/3-Runx2 signaling axis.
Wang X, Chen Y, Cheng Z, Cao Z, Cheng S, Xin C, Zhang J, Zhang F, Chen Y, Wang J, Li S, Li Y, Wang W
Journal of ethnopharmacology 2026 Jan 10;354:120514
Journal of ethnopharmacology 2026 Jan 10;354:120514
Targeted inflammatory microenvironment remodeling and NIR-II photothermal therapy for abdominal aortic aneurysm.
Liu Y, Qiu P, Hao H, Ding A, Wu Z, Lei J, Peng Z, Pu H, Zeng C, Guo H, Wu X, Lu H, Qin J, Wang R, Liu H, Ye K, Lu X
Materials today. Bio 2026 Feb;36:102770
Materials today. Bio 2026 Feb;36:102770
WTAP Contributes to Periodontitis Pathogenesis by Promoting PDLSC Senescence and Impairing Osteogenic Differentiation via m6A-Dependent Regulation of TP53BP1.
Xiong M, Wang T, Liu Y
Immunity, inflammation and disease 2026 Feb;14(2):e70335
Immunity, inflammation and disease 2026 Feb;14(2):e70335
Efferocytosis-Driven Polyamine Metabolism in Macrophages Enhances Cancer Stem Cell Enrichment after Chemotherapy in Ovarian Cancer.
Li W, Ying F, Pang X, Wu Q, Li G, Huang L, Xin J, Liu X, Liu P, Xu X, Tan S, Gao Y, Liu T, Sun S, Wang X, Wen Y, Cai L, Du S, Zhang Y, Cai J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(8):e12508
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(8):e12508
Citrate-coated Prussian blue nanozyme hitchhikes neutrophils to ameliorate calcium oxalate crystal-induced kidney injury via inhibiting pyroptosis and NETosis.
Ba X, Yang X, He Y, Ye T, Zeng X, Zhong Z, Guo X, Tang K
Journal of nanobiotechnology 2026 Feb 7;24(1)
Journal of nanobiotechnology 2026 Feb 7;24(1)
Single-Nucleus RNA Sequencing Reveals SPP1(+) Macrophages Induce Cardiomyocyte Apoptosis to Promote Atrial Fibrillation Susceptibility.
Wang W, Dong Y, Yi H, He L, Jiang Y, Long L, Xia Z, Li J
Journal of cardiovascular development and disease 2026 Feb 5;13(2)
Journal of cardiovascular development and disease 2026 Feb 5;13(2)
C5aR1(+) microglia exacerbate neuroinflammation and cerebral edema in acute brain injury.
Zhou J, Ma S, Feng D, Tian Y, Li L, Guo H, Shi Y, Cui W, Dong J, Hao S, Guo C, Xu M, Han L, Bai H, He D, Cui X, Chen L, Wu X, Gao F, Hu Q, Zhang Z, Wang K, Zhou G, Feng T, Xue D, Lin Q, Wang L, Gao L, Heng L, Zhao T, Luo T, Tian B, Zhang X, Guo W, Li Z, Liu H, Ge S, Liu Q, Qu Y
Neuron 2026 Feb 4;114(3):444-462.e9
Neuron 2026 Feb 4;114(3):444-462.e9
ANGPTL8 accelerates bone loss in diabetic mice by promoting osteoclastic differentiation and inhibiting osteoblastic differentiation through AMPK pathway-mediated metabolic reprogramming.
Tuo P, Mu W, Bai X, Wang S, Hu L, Xu Y, Mao R, Liu Y, Yuan Y, Zhang Q, Guo X, Ma S, Wang X
Cellular and molecular life sciences : CMLS 2026 Feb 23;83(1)
Cellular and molecular life sciences : CMLS 2026 Feb 23;83(1)
Supramolecular delivery of senolytics enables targeted anti-senescence therapy and accelerated fracture healing.
Fan Y, Wang ZH, Zhang X, Dong Y, Liu X, Luo G, Yang H, Li H, Wang Z, Tang Q, Jin X, Guo DS, Sun T
Journal of nanobiotechnology 2026 Feb 18;24(1)
Journal of nanobiotechnology 2026 Feb 18;24(1)
Discovery of 8-quinolinesulfonamide phenylimidazole-based PKM2 agonists for the prevention and delay of aortic dissection.
Li J, Yang Y, Cheng L, Xu X, Zhong K, Wang T, Chen K, Zhang C, He C, Xu J, Xu S, Luo S
European journal of medicinal chemistry 2026 Feb 15;304:118479
European journal of medicinal chemistry 2026 Feb 15;304:118479
The p75 neurotrophin receptor controls the skeletal stem cell niche through sensory innervation.
Wu Z, Li N, Luo Z, Chen Z, He X, Shi F, Han J, Huang H, Shi B, Zhang L, Li Y, Shen J, Bok S, Sun J, Niu X, Mo K, Yin P, Leng L, Wang X, Zhang J, Chen L, Zhou D, Cheng W, Huang J, Greenblatt MB, Xu R
Developmental cell 2026 Feb 11;61(2):259-275.e7
Developmental cell 2026 Feb 11;61(2):259-275.e7
The promoting roles of GLP1R and GIPR in stemness maintenance and multiple lineage-specific differentiation of PDLSCs.
Shen Y, Zhang M, Yang T, Wu Y, Qiu Y, Zhang L, Li F, Chen M, Chen Q, Wei W, Li H, Shen Y
Cellular & molecular biology letters 2026 Feb 11;31(1):22
Cellular & molecular biology letters 2026 Feb 11;31(1):22
Pulmonary macrophage-targeted RNAi and mRNA co-delivery via SORT lipid nanoparticles enhances immunotherapy in lung cancer.
Liang Q, Peng Y, Zhao L, Yang Z, Chen X, Li J, Wu Z, Chen K, Zhou B, Liu Y, Hu B, Qu C, Zhang M, Gao S
Journal of controlled release : official journal of the Controlled Release Society 2026 Feb 10;390:114519
Journal of controlled release : official journal of the Controlled Release Society 2026 Feb 10;390:114519
Integration of Multi-Omics and Machine Learning Identifies TGFB1 and SERPINE1 as Biomarkers of Vascular Smooth Muscle Cell Senescence in Intracranial Aneurysms.
Qiu H, Chen K, Chen Y, Yu Y, Ma X, Yuan Z, Li M, Zhuang J, Zhang M, Su W, Wang Y, Wang D, Zhong W
Translational stroke research 2026 Feb 10;17(1):24
Translational stroke research 2026 Feb 10;17(1):24
FUNDC2 contributes to hypertensive vascular remodeling by regulating mitochondrial dynamics and ferroptosis in perivascular adipose tissue.
Jin Y, Song T, Jiang T, Wei Y, Bao Y, Zhu Z, Zhou R, Wang D, Zhao Y, Li H, Fu Y
Clinical and experimental hypertension (New York, N.Y. : 1993) 2026 Dec 31;48(1):2610587
Clinical and experimental hypertension (New York, N.Y. : 1993) 2026 Dec 31;48(1):2610587
A composite hydrogel enables the spatiotemporal delivery of distinct cytokines to drive the native vascularized bone regeneration.
Zhou C, Bai J, Zhu J, Chen J, Jin X, Wang K, Jiang X, Chen H, Wu X, Hu B, Li R, Zhang M, Chen E, Xue D, Yu X, Zhang H, Pan Z, Xu J
Bioactive materials 2026 Aug;62:463-479
Bioactive materials 2026 Aug;62:463-479
PRSS22 inhibits HMOX1-mediated ferroptosis and induces osteopontin cleavage to promote M2 macrophage polarization and colitis-associated carcinogenesis.
Kuang Z, Su Q, Liang W, Shen K, Xie J
Oncogene 2026 Apr;45(14):1275-1286
Oncogene 2026 Apr;45(14):1275-1286
3D-printed titanium scaffolds coated with a multifunctional photothermal-responsive hydrogel promote osteoporotic bone defect repair.
Wang C, Wang Y, Li X, Cao H, Wang C, Han S, Chen H, Zhao X, Yang S
Materials today. Bio 2026 Apr;37:102879
Materials today. Bio 2026 Apr;37:102879
Graphene oxide coating on two-dimensional glass substrates and three-dimensional zirconia scaffolds for bone tissue regeneration.
Liu K, Tian Y, Mu R, Wang X, Xin M, Ding H, Qian Y, Hu Z, Zeng C, Wei X, Shuai Y, Jin L
Materials today. Bio 2026 Apr;37:102852
Materials today. Bio 2026 Apr;37:102852
Ultrasound-activated piezoelectric Silk-PVDF hydrogel reprograms the osteoimmune microenvironment via NRF2 signaling for accelerated bone regeneration.
Mo G, Qing L, Zhang C, Huang L, Yan H, Lu S, Zhang Y, Chen W, Xiang X, Wang N, Han G, Li Y, Jiang L, Zhang J
Materials today. Bio 2026 Apr;37:102779
Materials today. Bio 2026 Apr;37:102779
Dual-release 3D-printed porous Ti-6Al-4V implant with drug-eluting photothermal micro-nanotopographies: combating osteosarcoma recurrence, infections, and enhancing osteogenesis.
Ji Z, Wan Y, Zou Y, Wang H, Liang X, Liu P
Biomaterials 2026 Apr;327:123749
Biomaterials 2026 Apr;327:123749
Sparcl1 mitigates abdominal aortic aneurysm through inhibiting lymphangiogenesis-mediated TLS formation.
Chen MH, Hua YJ, Li Y, Lei Y, Zhou SY, Hu XD, Hu DH, Dong ZH, Lu Y, Zhuang T, Ruan CC
Nature immunology 2026 Apr;27(4):738-749
Nature immunology 2026 Apr;27(4):738-749
ZFP36L1 promotes non-small cell lung cancer progression under hypoxia by modulating CXCL9:SPP1 polarity: A single-cell transcriptomic study.
Wang L, Chen B, He J, Lin C, Shen W, Lv W, Wang L, Hu J
Clinical and translational medicine 2026 Apr;16(4):e70642
Clinical and translational medicine 2026 Apr;16(4):e70642
Bioinspired Engineering of Streamlined Skeletal Interoception: Neural Bioprinted Piezoelectric Scaffolds for Neuro-Vascularized Bone Regeneration.
Su Y, Wang H, Liu W, Chen K, Min Y, Zhu J, Li X, Su A, Yang H, Yang L, Ji Y, Zhang Y, Zheng J, Yang C, He C, Li T, Chen S, Wu T, Chen X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(21):e24181
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(21):e24181
Sr²⁺-coordinated asiatic acid/silk fibroin hybrid hydrogels for enhanced osteogenesis and antibacterial therapy in infective bone defects.
Qin HJ, He SY, Zhao SB, Xiao TH, Cui FT, Zhang LY, Chen GY, Chen JY, Dai DM, Liu XY, Hu XJ
Colloids and surfaces. B, Biointerfaces 2026 Apr 7;265:115690
Colloids and surfaces. B, Biointerfaces 2026 Apr 7;265:115690
A single-cell multiomic analysis identifies molecular and gene-regulatory mechanisms dysregulated in developing Down syndrome neocortex.
Vuong CK, Weber A, Seong P, Matoba N, Chen YJ, Peyer J, Younesi S, Salinda A, Gomez D, Rivas G, Morales A, Shafie B, Zhang P, Nichterwitz S, Qi L, Fernandez NT, Friedman E, Love MI, Gandal MJ, Geschwind DH, Lowry WE, Stein JL, de la Torre-Ubieta L
Science (New York, N.Y.) 2026 Apr 23;392(6796):eaea1259
Science (New York, N.Y.) 2026 Apr 23;392(6796):eaea1259
Synergistic Antibacterial and Osteogenic Activities of Cu/Sr-Empowered 13-93 Bioglass in PMMA Composites for Sequential Promotion of Infectious Osseointegration.
Li Y, Yu J, Dong Z, Feng Y, Hou X, Xing B
ACS applied materials & interfaces 2026 Apr 15;18(14):20228-20246
ACS applied materials & interfaces 2026 Apr 15;18(14):20228-20246
QiangGuYin-containing serum improves osteogenic differentiation via regulating osteoclast-derived exosomal miR-27b-3p.
Tang B, Hu S, Yuan Y, Li J, Huang X, Zhou H, Huang Z, Li W, Ye B, Liu K, Mao Y, Shi X
Journal of molecular histology 2026 Apr 10;57(2)
Journal of molecular histology 2026 Apr 10;57(2)
Loss of Gαq reshapes fibroblast traits and drives tumor-stroma remodeling in oral cancer progression.
Navarro-Lérida I, Huertas-Lárez R, Paredes-García G, García-Mateos D, Jiménez-López MI, Prieto-Fernández L, Pascual A, Ávila-Oca V, López JA, Del Pozo MA, Álvarez-Teijeiro S, García-Pedrero JM, García-Escudero R, Mayor F Jr, Ribas C
EMBO reports 2026 Apr 10;
EMBO reports 2026 Apr 10;
A Noninvasive Menstrual Blood-Based Diagnostic Platform for Endometriosis Using Digital Droplet Enzyme-Linked Immunosorbent Assay and Single-Cell RNA Sequencing.
Wang H, Gan Z, Wang Y, Hu D, Zhang L, Ye F, Duan P
Research (Washington, D.C.) 2025;8:0652
Research (Washington, D.C.) 2025;8:0652
Novel lncRNA LncMSTRG.11341.25 Promotes Osteogenic Differentiation of Human Bone Marrow Stem Cells via the miR-939-5p/PAX8 Axis.
Ni F, Li J, Yin Q, Chen Y, Shao Z, Wang H
Research (Washington, D.C.) 2025;8:0601
Research (Washington, D.C.) 2025;8:0601
Identification of pivotal genes and crucial pathways in liver fibrosis through WGCNA analysis.
Zhang X, Yang F, Han L, Su Q, Gao Y, Wu R, Wang D, Li W, Zheng K, Liu F, Ran J
Technology and health care : official journal of the European Society for Engineering and Medicine 2025;33(1):431-448
Technology and health care : official journal of the European Society for Engineering and Medicine 2025;33(1):431-448
A Biodegradable Zinc Alloy Membrane with Regulation of Macrophage Polarization for Early Vascularized Bone Regeneration.
Yi L, Tang R, Shao C, Chen C, Tang J, Liao L, Chen L
Biomaterials research 2025;29:0223
Biomaterials research 2025;29:0223
A pH-Responsive Polyetheretherketone Implant Modified with a Core-Shell Metal-Organic Framework to Promote Antibacterial and Osseointegration Abilities.
Ma S, Yao S, Li Y, Yang Y, Tong T, Zheng H, Ma B, Wei P, Di Z, Zhao B, Deng J
Biomaterials research 2025;29:0188
Biomaterials research 2025;29:0188
Endothelial TIE2 Mutation Induced Contraction Deficiency of Vascular Smooth Muscle Cells via Phenotypic Transition Regulation in Venous Malformations.
Du Z, Yu F, You YH, Zhao ZY, Tian ZW, Xiao M, Wang YA
International journal of medical sciences 2025;22(10):2518-2532
International journal of medical sciences 2025;22(10):2518-2532
Integrin β3-mediated platelet extracellular vesicle adhesion facilitates vascular smooth muscle cell dysfunction in postinjury intimal hyperplasia.
Zhuang F, Liu ZT, Zhou G, Liang F, Wang YH, Chen L, Zhang WF, Shen LH, Lu YQ, Huo HH, Shi X, Fang L, He B
International journal of biological sciences 2025;21(6):2380-2395
International journal of biological sciences 2025;21(6):2380-2395
Ti(3)C(2)Tx MXene Potentiates PSAT1-Mediated Osteogenesis Through miR-665/GSK-3β/β-Catenin Axis to Counteract Inflammation-Induced Bone Loss.
Zhang J, Wang X, Xiao J, Hong H, Chen J, Wu C, Xu G, Cui Z
International journal of nanomedicine 2025;20:11151-11168
International journal of nanomedicine 2025;20:11151-11168
Osteopontin as a Novel Biomarker in Distinguishing Chronic Rhinosinusitis with Nasal Polyp Endotypes and Predicting Disease Severity.
Liu P, Liu M, Sun Y, Yu M, Lei W, Xu Y
International archives of allergy and immunology 2025;186(5):473-483
International archives of allergy and immunology 2025;186(5):473-483
Single-Cell RNA Sequencing Reveals Microglial Heterogeneity and Functional States After Cerebral Ischemia-Reperfusion Injury.
Tang Y, Zhang Q, Qu Y, Yi L, Li F, Qu C, Shi S, Pan BF, Wen S, Sun R, Pan Y
Journal of inflammation research 2025;18:16931-16956
Journal of inflammation research 2025;18:16931-16956
Single-cell RNA-seq reveals a repair pattern in cystic lesions in steroid induced osteonecrosis of the femoral head.
Peng P, Tian J, Lin K, Fang W, Yao F, Yang X, Hou W, Xiao F, Lu S, He W, He M, Xiao H, Wei Q
Frontiers in immunology 2025;16:1626337
Frontiers in immunology 2025;16:1626337
Identification of a stromal immunosuppressive barrier orchestrated by SPP1(+)/C1QC(+) macrophages and CD8(+) exhausted T cells driving gastric cancer immunotherapy resistance.
Ma G, Liu X, Jiang Q, Li S, Wu Q, Liang B, Sun F, Gu C, Liao W, Zhang Z, Shi M, Huang Q
Frontiers in immunology 2025;16:1618591
Frontiers in immunology 2025;16:1618591
Identification of immune-related diagnostic genes and immune cell infiltration in aseptic loosening of prostheses after total hip arthroplasty by integrated bioinformatics analysis and experimental confirmation.
Liu Y, Liang X, Qiang S, Dong Y, Zhao X, Ma L, Yan Z, Yue S, Huang Y, Zheng J
Frontiers in genetics 2025;16:1597219
Frontiers in genetics 2025;16:1597219
The dual role of CXCL9/SPP1 polarized tumor-associated macrophages in modulating anti-tumor immunity in hepatocellular carcinoma.
Gu Y, Zhang Z, Huang H, Zhu W, Liu H, Zhang R, Weng N, Sun X
Frontiers in immunology 2025;16:1528103
Frontiers in immunology 2025;16:1528103
O-GlcNAcylation-dependent liquid-liquid phase separation regulates the nuclear translocation of YAP to exacerbate vascular neointimal hyperplasia.
Weng P, Wen Y, Yuan Z, Ma L, Yang L, Li C, Zhang W, Yu C
Theranostics 2025;15(16):7956-7972
Theranostics 2025;15(16):7956-7972
Prognostic value and immune infiltration of anoikis-related genes in osteosarcoma.
Mo J, Li H, Wang H, Fang X, Ma J, Chen K
Frontiers in medicine 2025;12:1669470
Frontiers in medicine 2025;12:1669470
METTL14 promotes TBK1 mRNA stability through IGF2BP3-recognized m6A modification and enhances mitophagy in BMSCs.
Shen Y, Wang L, Guo Z, Wang J, Zhang R, Tang C, Wu J
Cellular signalling 2025 Sep;133:111873
Cellular signalling 2025 Sep;133:111873
Single-cell transcriptomic analyses provide insights into SPP1(+) TAM-mediated immune suppression and CD8(+) T cell dysfunction in lung cancer.
Almgrami RT, Zhang T, Zhao Q, You M, Liu J, Zhang Y
Cancer immunology, immunotherapy : CII 2025 Sep 29;74(10):319
Cancer immunology, immunotherapy : CII 2025 Sep 29;74(10):319
Mechanism of Piezo1 regulating chondrocyte mitochondrial function and promoting fracture healing through β-catenin/LARS2 signaling pathway.
Zhang T, Lv H, Jia S, Wang L, Liu W, Ding K, Du X, Hou G, Hou Z, Zhang Y, Zou W, Chen W, Zhu Y
Bone research 2025 Sep 24;13(1):79
Bone research 2025 Sep 24;13(1):79
Targeting USP21 to inhibit abdominal aortic aneurysm progression by suppressing the phenotypic transition of vascular smooth muscle cells.
Zhang H, Yue H, Sun Y, Sun G, Yang K, Jiang T, Cui S, Liu Y, Guo Y, Zhang W, Zhang C, Chen Y, Xu F
Cell reports. Medicine 2025 Sep 16;6(9):102328
Cell reports. Medicine 2025 Sep 16;6(9):102328
In situ construction of ossification micro-units for critical bone regeneration via sustained lifting of epigenetic suppression.
Yang W, Ding T, Zhuang P, Chen Y, Zhang Y, Chen Z, Fan M, Viitala T, Wang Z, Cui W, Zhang H
Journal of controlled release : official journal of the Controlled Release Society 2025 Sep 10;385:113978
Journal of controlled release : official journal of the Controlled Release Society 2025 Sep 10;385:113978
Dimethyloxalylglycine regulates osteogenesis of dental pulp stem cells through PI3K/AKT signaling pathways.
Dong Q, Zhang H, Zhang Q, Fei X, Ruan J, He L
Tissue & cell 2025 Oct;96:103012
Tissue & cell 2025 Oct;96:103012
RNF213 Knockdown and Inflammation Promote Angiogenesis and Phenotype Switching by JAK2/STAT3 Pathway in Moyamoya Disease.
Shen J, Wang Y, Qin Y, Chen G, Xu J, Li Y, Hou Y, Liu Y, Liu W
Molecular neurobiology 2025 Oct;62(10):12938-12950
Molecular neurobiology 2025 Oct;62(10):12938-12950
Gut microbiota diversity and metabolomics analysis of curcumin's alleviation of abdominal aortic aneurysm progression.
Cheng S, Hao X, Wang L, Jiang B, Xin S
Molecular and cellular biochemistry 2025 Oct;480(10):5459-5472
Molecular and cellular biochemistry 2025 Oct;480(10):5459-5472
PKA-driven SPP1 activation as a novel mechanism connecting the bone microenvironment to prostate cancer progression.
Sanchis P, Sabater A, Lechuga J, Rada J, Seniuk R, Pascual G, Gatti M, Bizzotto J, Shepherd PDA, Yang J, Cotignola J, Vazquez E, Mateo J, Valacco P, Labanca E, Logothetis C, Gueron G, Anselmino N
Oncogene 2025 Oct;44(38):3568-3579
Oncogene 2025 Oct;44(38):3568-3579
GNAS/PKA signaling promotes aberrant osteochondral differentiation of Gli1(+) tendon sheath progenitors.
Chen L, Peng C, Chai L, Zhang R, Zhu C, Wang H, Cheng Q, Yan Y, Shen C, Zheng H, Yang J, Fan H, Kan C
The EMBO journal 2025 Oct;44(20):5890-5917
The EMBO journal 2025 Oct;44(20):5890-5917
Dual stimulus-responsive dECM cryogel sequentially regulate bone microenvironment for one-step surgical therapy of chronic osteomyelitis.
Liu H, Liu S, Liao L, Liao H, Pan W, Hu J
Materials today. Bio 2025 Oct;34:102243
Materials today. Bio 2025 Oct;34:102243
Synergistic exacerbation of periprosthetic osteolysis by inflammatory bowel disease and titanium ions: Impaired osteogenesis of BMSCs via PI3K/AKT signaling.
Ming P, Li K, Zhu W
Materials today. Bio 2025 Oct;34:102236
Materials today. Bio 2025 Oct;34:102236
TGF-β1/IL-11 positive loop between renal tubular epithelial cell and fibroblast promotes the ectopic calcification of renal interstitial fibroblasts in rats.
Zhong J, Duan X, Yang H, Liu Z, Zhong W, Zhang Z, Huang Y, Zeng H, Zhao H, Liu Y, Liu Y, Zeng G, Zhao Z
Biochemical pharmacology 2025 Oct;240:117074
Biochemical pharmacology 2025 Oct;240:117074
Profibrotic impact of PAD4-driven macrophage extracellular traps in ulcerative colitis.
Wang Z, Shi R, Shi Y, Sun T, Shen Y, Wu C, Yang Y, Fan H, Wu J
Pharmacological research 2025 Oct;220:107933
Pharmacological research 2025 Oct;220:107933
A Novel Injectable Composite Hydrogel HAp-GelMA Co-Doped Magnesium/Zinc Promotes Bone Generation and Angiogenesis Synergistically.
Qiang L, Zhang T, Zhang Q, Yang T, Shan J, Shen G, Kong W, Wei J, Wang J, Liu Y, Niu H, Zheng P
Advanced healthcare materials 2025 Oct;14(27):e01008
Advanced healthcare materials 2025 Oct;14(27):e01008
POSTN-Mediated Interplay of M1 Polarized Macrophage with Tendon-Derived Stem Cells to Drive Traumatic Heterotopic Ossification Formation through PTK7/ATK Signaling?
Liu H, Li X, Li M, Sun Z, Wang X, Li J, Xu B, Chen Q, Fan C, Ruan H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(40):e07951
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(40):e07951
Single-cell RNA sequencing reveals that Danggui Buxue Tang decoction facilitates wound healing after anal fistula by promoting M2 macrophage polarization.
Pang X, Wang Y, Guo J
Hereditas 2025 Oct 9;162(1):204
Hereditas 2025 Oct 9;162(1):204
Linoelaidic acid alleviates COM-induced kidney injury and crystal deposition via the PPARγ/MAPK signaling pathway.
Qi W, Yan X, Li C, Jing J, Zhang Y, Xi J, Liang C
Urolithiasis 2025 Oct 23;53(1):205
Urolithiasis 2025 Oct 23;53(1):205
Pak4-mediated crosstalk between necroptotic macrophages and tendon stem/progenitor cells contributes to traumatic heterotopic ossification formation.
Sun Z, Liu H, Xu Y, Chen Q, Luo G, Yuan Z, Chen Z, He K, Fan C, Li J, Ruan H
Bone research 2025 Oct 20;13(1):88
Bone research 2025 Oct 20;13(1):88
BMDMs in metabolic memory impair fracture healing in diabetes.
Zhang D, Liu C, Yuan Y, Su J, Wang Z, Jian C, Yu A
Stem cell research & therapy 2025 Oct 14;16(1):562
Stem cell research & therapy 2025 Oct 14;16(1):562
Altered pattern of proteolysis in rhegmatogenous retinal detachment by mining of N-termini datasets from vitreous humor proteome.
Zingale GA, Giammaria S, Pandino I, Placentino L, Ripandelli G, Tundo GR, Grasso G, Bocedi A, Bell PA, Rossi T, Sbardella D
Scientific reports 2025 Oct 14;15(1):35848
Scientific reports 2025 Oct 14;15(1):35848
A Positive Feedback Loop Between SPP1 (+)Macrophages and Tumor Cells Promotes Head and Neck Squamous Cell Carcinoma Progression.
Liu C, Li C, Wu K, Guo H, Zhang J
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2025 Nov;54(10):972-981
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2025 Nov;54(10):972-981
Bicontinuous Interconnected Porous Biomaterials for Tissue Engineering and Regeneration.
Banerjee A, Khanal A, Okoro PD, Kharal SP, Dalsania K, Kanjilal B, Iragavarapu SB, Chen Y, Unagolla JM, Liu HH, Morgan JT, Hesketh RP, Pezhouman A, Ardehali R, Anvari B, Haase MF, Noshadi I
Small science 2025 Nov;5(11):2500207
Small science 2025 Nov;5(11):2500207
Osteoblast-Mesenchymal Stem Cell Coculture Drives In Vitro Osteogenesis in 3D Bioprinted Periosteum.
McLoughlin ST, Wilcox P, Caccamese JF, Fisher JP
Tissue engineering. Part A 2025 Nov;31(21-22):1239-1252
Tissue engineering. Part A 2025 Nov;31(21-22):1239-1252
Biomimetic Scaffolds with Dual Gradients of Biological Effectors for Tendon-to-Bone Repair.
Hao M, Chen Y, Thomopoulos S, Xia Y
Advanced healthcare materials 2025 Nov;14(28):e2503171
Advanced healthcare materials 2025 Nov;14(28):e2503171
MYST1-Mediated Lysine Acetylation Stabilizes KLF4 to Promote Intimal Hyperplasia.
Wang S, Liu Z, Wen J, Zhang C, Wu F, Zeng Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Nov 30;39(22):e71247
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Nov 30;39(22):e71247
Antihypertension and Improvement Effects of Hexapeptide APPLRP on Exosomes-Mediated Vascular Endothelial Inflammation in Spontaneously Hypertensive Rats.
Cai Q, Zhang T, Zhai K, Guo B, Gong Q, Yang Y, Ding YY, Gu Z, Song T
Journal of agricultural and food chemistry 2025 Nov 26;73(47):30458-30472
Journal of agricultural and food chemistry 2025 Nov 26;73(47):30458-30472
FABP3 Mediates Lipid Droplet Accumulation and Adhesive Capacity in Bovine Endometrial Epithelial Cells via PGE(2)/PTGER4/PPAR Axis.
Zhang B, Yan Y, Cheng M, Guo T, Gao K, Wang A, Lin P, Zhou D, Jin Y
Animals : an open access journal from MDPI 2025 Nov 26;15(23)
Animals : an open access journal from MDPI 2025 Nov 26;15(23)
Deferoxamine improves femoral trochlear dysplasia following patellar dislocation through HIF-1α/VEGF-mediated angiogenesis-osteogenesis coupling.
Li Y, Ni Z, Fu T, Xu C, Zhao Z, Kang H, Wang F
Journal of orthopaedic surgery and research 2025 Nov 25;20(1):1034
Journal of orthopaedic surgery and research 2025 Nov 25;20(1):1034
Assessing the toxicological effects of exposure to environmental pollutants PET-MPs on vascular diseases: insights from network toxicology, molecular docking, molecular dynamics, and experimental validation.
Xu H, Chen S, Wang X, Lian H, Zhang S, Liu Z, Guo R
Environmental pollution (Barking, Essex : 1987) 2025 Nov 15;385:127082
Environmental pollution (Barking, Essex : 1987) 2025 Nov 15;385:127082
Berberine ameliorates atherosclerosis by inhibiting the phenotypic transition of vascular smooth muscle cells via suppression of the JAK2/STAT3 signaling pathway.
Zheng J, Wang T, Zhou Y, Chen Y, Shen X, Jin B, Han X, Hua C, Xie J
European journal of pharmacology 2025 Nov 15;1007:178234
European journal of pharmacology 2025 Nov 15;1007:178234
Curcumenol exerts anti-pulmonary fibrosis effects through modulation of the immune signature target SPP1: based on comprehensive bioinformatics and experiments validation.
Li C, Wen R, Xiong Y, Tan QW, Zhai XY, Xiong Y, Dai LS
International immunopharmacology 2025 Nov 14;165:115469
International immunopharmacology 2025 Nov 14;165:115469
Single-cell and spatial RNA sequencing identify divergent microenvironments and progression signatures in early- versus late-onset prostate cancer.
Cheng Y, Liu B, Xin J, Wu X, Li W, Shang J, Wu J, Zhang Z, Xu B, Du M, Cheng G, Wang M
Nature aging 2025 May;5(5):909-928
Nature aging 2025 May;5(5):909-928
An ultrasound-driven PLGA/Zn-KNN hybrid piezoelectric scaffold with direct and immunoregulatory antibacterial activity for bone infection.
Zheng Y, Wang S, Jin W, Li Z, Yang G, Li X, Li N, Wang Y, Sheng F, Song Z
Bioactive materials 2025 May;47:295-312
Bioactive materials 2025 May;47:295-312
JOSD2 inhibits angiotensin II-induced vascular remodeling by deubiquitinating and stabilizing SMAD7.
Shen SR, Huang ZQ, Yang YD, Han JB, Fang ZM, Guan Y, Xu JC, Min JL, Wang Y, Wu GJ, Xiao ZX, Luo W, Huang ZQ, Liang G
Acta pharmacologica Sinica 2025 May;46(5):1275-1288
Acta pharmacologica Sinica 2025 May;46(5):1275-1288
A novel 5-differentially expressed gene (DEG) signature predicting the prognosis in patients with metastatic liver malignancies and the prognostic and therapeutic potential of SPP1.
Liu J, Yu Z, Liu Q, Dou C, Cao P, Xie X
International journal of clinical oncology 2025 May;30(5):956-973
International journal of clinical oncology 2025 May;30(5):956-973
Smooth muscle cell Piezo1 is essential for phenotypic switch and neointimal hyperplasia.
Zhang FR, Tang J, Lai Y, Mo SQ, Lin ZM, Lei QQ, Han CC, Zhou AD, Lv XF, Wang C, Ou JS, Zhou JG, Pang RP
British journal of pharmacology 2025 May;182(9):2031-2048
British journal of pharmacology 2025 May;182(9):2031-2048
Integrated multi-omics characterization of neuroblastoma with bone or bone marrow metastasis.
Huang K, Yang L, Ma Y, Cao L, Li S, Zhao Z, Zhou J, Wang S
Genes & diseases 2025 May;12(3):101511
Genes & diseases 2025 May;12(3):101511
Preparation, Physicochemical Characterization, and In Vitro and In Vivo Osteogenic Evaluation of Reinforced PLLA-PLCL/HA Resorbable Membranes.
Fu Z, Wang J, Wu Y, Zeng W, Zhang C, Sun Y, Fan X, Huang Y, Deng F, Xu J
Journal of biomedical materials research. Part A 2025 May;113(5):e37925
Journal of biomedical materials research. Part A 2025 May;113(5):e37925
Melatonin Promotes Osteogenic Differentiation of Rat Adipose-Derived Stem Cells via the p38/MAPK Signaling Pathway.
Meng S, Han S, Kong M, Liu Z, Lin A, Qu C, Li L, Ma X, Wang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70647
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70647
Mineralocorticoid receptor antagonism attenuates arteriovenous fistula stenosis by modulating the phenotype of vascular smooth muscle cells.
Liu Y, Chen B, Chen K, Wang Y, Zhou C, Liang X, Wang K, Wang P
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2025 May 30;40(6):1124-1136
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2025 May 30;40(6):1124-1136
PIASy deficiency mitigates thoracic aortic aneurysm formation via the TGF-β/Smad2/3 pathway.
Shen D, Zheng H, Shao K, Zhu J, Hou Y, Ding Y
Journal of thoracic disease 2025 May 30;17(5):3400-3409
Journal of thoracic disease 2025 May 30;17(5):3400-3409
IGF-1 signaling pathway activation promotes axonal regeneration and repair: A mechanism study on catalpol-induced functional recovery after ischemic stroke.
Liu Y, Wu D, Hua H, Mei S, Yan X, Xu X, Li L, Wu Y, Zhu J, Wu M, Li W
Journal of ethnopharmacology 2025 May 28;348:119808
Journal of ethnopharmacology 2025 May 28;348:119808
An Asymmetric Zn Membrane with Degradability, Antimicrobial, and Bone Immunomodulation for Guided Bone Regeneration.
Ma S, Zhao Z, Shang Y, Qi M, Xu S, Yao S, Li Y, Wang X, Tong T, Zheng H, Ma B, Yang Y, Wu J, Liu Z, Deng J
ACS applied materials & interfaces 2025 May 28;17(21):31640-31653
ACS applied materials & interfaces 2025 May 28;17(21):31640-31653
Geniposide ameliorates cholesterol accumulation and promotes osteoblast differentiation by mediating the GLP-1R/AMPK/SREBP2 pathway.
Zhan W, Wu L, Li S, Yin G, Zhou J, Wu Z
Journal of orthopaedic surgery and research 2025 May 26;20(1):514
Journal of orthopaedic surgery and research 2025 May 26;20(1):514
Orai1 Participates in Coronary Artery Dysfunction Caused by Hypertension via Regulating Smooth Muscle Cell Phenotype Transformation.
Wang H, Liang MY, Cai YJ, Deng CY, Yang H, Mai LP, Zhang MZ, Kuang SJ, Rao F, Xu JS
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 15;39(9):e70576
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 15;39(9):e70576
Direct microglia replacement reveals pathologic and therapeutic contributions of brain macrophages to a monogenic neurological disease.
Aisenberg WH, O'Brien CA, Sangster M, Yaqoob F, Zhang Y, Temsamrit B, Thom S, Gosse L, Chaluvadi S, Elfayomi B, Lee G, Polam V, Levitt EM, Liu G, Lombroso SI, Nemec KM, Clowry G, Nieves C, Rawat P, Church E, Martinez D, Shoffler C, Kancheva D, Petucci C, Taylor D, Kofler J, Erskine D, Movahedi K, Bennett ML, Bennett FC
Immunity 2025 May 13;58(5):1254-1268.e9
Immunity 2025 May 13;58(5):1254-1268.e9
High-Entropy Alloy/Zinc Sulfide Heterojunction-Based Hydrogel for Eliminating Bacteria and Stimulating Osteoblast Response.
Lin Y, Zhang Q, Xie S, Song A, Xi X, Dai Y, Wei J, Zhao J
ACS biomaterials science & engineering 2025 May 12;11(5):2958-2973
ACS biomaterials science & engineering 2025 May 12;11(5):2958-2973
Low-frequency, mild-gradient chronic intermittent hypoxia still induces liver fibrogenesis in mice on a high-fat diet.
Kudo J, Hirono H, Ohkoshi S
Biochemical and biophysical research communications 2025 May 1;761:151744
Biochemical and biophysical research communications 2025 May 1;761:151744
5,7-Dihydroxy-4-Methylcoumarin enhances osteogenesis and ameliorates osteoporosis via the AKT1 pathway.
Diao H, Yang H, Yu B, Fan Y, Li S, Fan J, Xiao D, Zhao Y, Guo M, Zhang Y, Huang S, Tang Q, Li SS, Sun T, Jin X
Biochemical pharmacology 2025 Mar;233:116752
Biochemical pharmacology 2025 Mar;233:116752
SERCA2 dysfunction accelerates angiotensin II-induced aortic aneurysm and atherosclerosis by induction of oxidative stress in aortic smooth muscle cells.
Wang L, Song J, Yang Z, Zhang H, Wang Y, Liu J, Wang S, Shi J, Tong X
Journal of molecular and cellular cardiology 2025 Mar;200:68-81
Journal of molecular and cellular cardiology 2025 Mar;200:68-81
The Effects of different forms of exercise during the early life on the bone microstructure of ovariectomized mice.
Wang Y, Zhang K, Gao W, Lin H, Li T, Liu TCY, Weng X, Yuan Y
Bone 2025 Mar;192:117364
Bone 2025 Mar;192:117364
MOF-818 Nanozyme Suppresses Calcium Oxalate Kidney Stones by Alleviating Oxidative Stress and Inflammatory Injury.
Tian Y, Ye Z, Wang X, Guan H, Liu W, Duan X, Liu Y, Zeng G, Liu H
Advanced healthcare materials 2025 Mar;14(8):e2401574
Advanced healthcare materials 2025 Mar;14(8):e2401574
A Highly Bioactive Organic-Inorganic Nanoparticle for Activating Wnt10b Mediated Osteogenesis by Specifically Anchor CCN3 Protein.
Qiu Y, Wang C, Yang Y, Xu S, Huang H, Zhang L, Lei B, Zhao F
Advanced healthcare materials 2025 Mar;14(7):e2404075
Advanced healthcare materials 2025 Mar;14(7):e2404075
Enhanced Vascular Smooth Muscle Cell and Extracellular Matrix Repair Using a Metal-Organic Framework-Based Co-Delivery System for Abdominal Aortic Aneurysm Therapy.
Lei J, Dong X, Huang Y, Wu Z, Peng Z, Li B, Wang R, Pan Y, Zheng X, Zhao Z, Lu X
Advanced healthcare materials 2025 Mar;14(6):e2402937
Advanced healthcare materials 2025 Mar;14(6):e2402937
METTL3-mediated m6A modification of circSTAT6 modulates miR-188-3p/Beclin1 axis to promote osteogenic differentiation of mesenchymal stem cells.
Luo Y, Shi Y, Wu Y, Cao H
Journal of orthopaedic surgery and research 2025 Mar 26;20(1):313
Journal of orthopaedic surgery and research 2025 Mar 26;20(1):313
ROS-responsive nanoparticles with selenomethionine for ferroptosis modulation in abdominal aortic aneurysm.
He H, Chen L, Peng J, Guo J, Xiao X, Dou C, Chen H, Zhan S, Han X, Yao W
iScience 2025 Mar 21;28(3):111880
iScience 2025 Mar 21;28(3):111880
Graphene oxide andin-situcarbon reinforced hydroxyapatite scaffolds via ultraviolet-curing 3D printing technology with high osteoinductivity for bone regeneration.
Zhao H, Niu X, Wei S, Lin W, Luo H, Zou B, Chen Q, Xing H, Lai Q
Biofabrication 2025 Mar 20;17(2)
Biofabrication 2025 Mar 20;17(2)
Vdr mediates Wnt signaling pathway to regulate odontoblasts differentiation during dentin apposition.
Wu Y, Zhu W, Wang L, Zhang W, Zhang K, Sun M, Guan J, Liu S, Liu Y
European journal of pharmacology 2025 Mar 15;991:177333
European journal of pharmacology 2025 Mar 15;991:177333
miR-138-5p inhibits healing of femoral fracture osteogenesis in rats by modulating osteoblast differentiation via SIRT1/FOXO1 axis.
Dai G, Jiang W, Feng B, Zhang L
Journal of orthopaedic surgery and research 2025 Mar 14;20(1):280
Journal of orthopaedic surgery and research 2025 Mar 14;20(1):280
Static Topographical Cue Combined with Dynamic Fluid Stimulation Enhances the Macrophage Extracellular Vesicle Yield and Therapeutic Potential for Bone Defects.
Huang H, Xiao L, Fang L, Lei M, Liu Z, Gao S, Lei Q, Lei J, Wei R, Lei Y, Xue L, Geng Z, Cai L, Yan F
ACS nano 2025 Mar 11;19(9):8667-8691
ACS nano 2025 Mar 11;19(9):8667-8691
NPC1L1 Drives Osteoporosis by Activating the C/EBPα/Cyp27a1/27-Hydroxycholesterol Axis: A Novel Therapeutic Target for Bone Loss.
Li B, Zhou W, Yu Y, Chen B, Lv Z, Zhang J, Zhang T, Sun S, Zhou L, Wang M
FASEB bioAdvances 2025 Jun;7(6):e70020
FASEB bioAdvances 2025 Jun;7(6):e70020
Magnetically bioprinted anisotropic hydrogels promote BMSC osteogenic differentiation for bone defect repair.
Xu R, Zhang H, Luo Y, Pan S, Zhang C, Wu X, Zhang G, Su C, Xia D
Materials today. Bio 2025 Jun;32:101885
Materials today. Bio 2025 Jun;32:101885
A novel strategy for bone defect repair: Stromal cell-derived factor 1α sustained-release acellular fish scale scaffolds combined with injection of bone marrow mesenchymal stem cells promote bone regeneration.
Su S, Bai J, Wang R, Gao S, Zhou R, Zhou F
Materials today. Bio 2025 Jun;32:101759
Materials today. Bio 2025 Jun;32:101759
Sequential SDF-1/CGRP-releasing smart composite hydrogel promotes osteoporotic fracture healing by targeting sensory nerve-regulated bone remodeling.
Wang Y, Pan Z, Wang Q, Shu Y, Tan Z, Chen Y, He J, Wang J, Wang J, Yan J
Materials today. Bio 2025 Jun;32:101750
Materials today. Bio 2025 Jun;32:101750
Harnessing engineered exosomes as METTL3 carriers: Enhancing osteogenesis and suppressing lipogenesis in bone marrow mesenchymal stem cells for postmenopausal osteoporosis treatment.
Li T, Zhao J, Yuan J, Ding R, Yang G, Cao J, Zhao X, Liu J, Liu Y, Xu P, Deng J, Miao X, Cheng X
Materials today. Bio 2025 Jun;32:101648
Materials today. Bio 2025 Jun;32:101648
Injectable bioresponsive bone adhesive hydrogels inhibit NLRP3 inflammasome on demand to accelerate diabetic fracture healing.
Xing X, Gong Z, Chen C, Lin Y, Liu P, Xiao T, Yu H, Li Y, Lin Y, Tan G, Ning C, Wu Z, Wang L, Zhou L
Biomaterials 2025 Jun;317:123059
Biomaterials 2025 Jun;317:123059
Inhibition of SFRP1 by microRNA‑206‑3p may be the underlying cause of osteosarcopenia.
Yu C, Lu Z, Du Y, Lv Y, Fang J, Zhao Y, Peng Z, Lu S
Biomedical reports 2025 Jun;22(6):103
Biomedical reports 2025 Jun;22(6):103
Macrophages-derived small extracellular vesicles regulate chondrocyte proliferation and affect osteoarthritis progression via upregulating Osteopontin expression.
Tu M, Liu AM, Huang W, Wang D, Chen HQ, Hu XY
Journal of cell communication and signaling 2025 Jun;19(2):e70008
Journal of cell communication and signaling 2025 Jun;19(2):e70008
Injectable Alginate/β-TCP Composite Hydrogel Incorporating P34HB/MgO+PEG Coaxial Electrospun Microfibers for Minimally Invasive Treatment of Osteonecrosis.
Zhou YH, Zou ZH, Teng JX, Wu ZY, Luo SW, Ning X, Ye C, Yang L, Toh WS
Advanced healthcare materials 2025 Jun;14(15):e2500617
Advanced healthcare materials 2025 Jun;14(15):e2500617
SOX3 facilitates granulosa cell proliferation and suppresses cell apoptosis through modulating PI3K/AKT pathway by targeting SPP1.
Cai R, Li C, Shi W, Xie F, Fan M, Zhang H, Liu Z, Chen Y, Hong Q
Cellular and molecular life sciences : CMLS 2025 Jun 30;82(1):266
Cellular and molecular life sciences : CMLS 2025 Jun 30;82(1):266
TAMs-derived SPP1, regulated by HIF-1α/STAT3 signaling pathway, influences colorectal cancer malignant progression by activation of EMT via integrin αvβ3.
Qu Y, Wang X, Li J, Luo H, Liu H, Wang T, Han X
International immunopharmacology 2025 Jun 26;159:114947
International immunopharmacology 2025 Jun 26;159:114947
STAT3-controlled CHI3L1/SPP1 positive feedback loop demonstrates the spatial heterogeneity and immune characteristics of glioblastoma.
Yu W, Gui S, Peng L, Luo H, Xie J, Xiao J, Yilamu Y, Sun Y, Cai S, Cheng Z, Tao Z
Developmental cell 2025 Jun 23;60(12):1751-1767.e9
Developmental cell 2025 Jun 23;60(12):1751-1767.e9
Mesenchymal stem cells attenuate hyperoxaluria-induced kidney injury and crystal depositions via inhibiting the activation of NLRP3 inflammasome.
Zou B, Wang D, Zhong J, He Z, Zhou Y, Yang H, Liu Y, Zeng G, Duan X
Life sciences 2025 Jun 15;371:123608
Life sciences 2025 Jun 15;371:123608
The Piezo1/Extracellular Signal-Regulated Kinase Signal Pathway Regulates Proliferation and Migration of Aortic Vascular Smooth Muscle Cells and Participates in Thoracic Aortic Aneurysm.
Nie W, Cao W, Zhuang Y, Yang S, Zhang H, Hu H, Shi C, Zhang H
Heart, lung & circulation 2025 Jul;34(7):704-718
Heart, lung & circulation 2025 Jul;34(7):704-718
Colchicine inhibits vascular calcification by suppressing inflammasome activation through the enhancement of the Sirt2-PP2Ac signaling pathway.
Yang S, Huang H, Jiang K, Peng Y, Liang Z, Gong X, Li L, Li Y, Zhang B, Chen Y, Yang X
The Journal of biological chemistry 2025 Jul;301(7):110381
The Journal of biological chemistry 2025 Jul;301(7):110381
UCP1 prevents the formation of thoracic aortic aneurysms and dissection by inhibiting the TLR4/NLRP3/IL-1β signaling pathway and VSMC phenotype switching in mice.
Xiang J, Yue H, Jiang D, Zheng S, Wu Z
Biochemical pharmacology 2025 Jul;237:116929
Biochemical pharmacology 2025 Jul;237:116929
Cytoplasmic and nuclear NFATc3 cooperatively contributes to vascular smooth muscle cell dysfunction and drives aortic aneurysm and dissection.
Liu X, Zhao L, Liu D, Zhao L, Tuo Y, Peng Q, Huang F, Song Z, Niu C, He X, Xu Y, Wan J, Zhu P, Jian Z, Guo J, Liu Y, Lu J, Liang S, Zheng S
Acta pharmaceutica Sinica. B 2025 Jul;15(7):3663-3684
Acta pharmaceutica Sinica. B 2025 Jul;15(7):3663-3684
Quercetin nanoformulation-embedded hydrogel inhibits osteopontin mediated ferroptosis for intervertebral disc degeneration alleviation.
Li J, Ren L, Wan L, Liu M, Zhao M, Lin Y, Zheng J, Tang Y, Luo Y, Ma Y, Wang L, Cao P, Chen Z, Ren W, Wang F
Journal of nanobiotechnology 2025 Jul 8;23(1):492
Journal of nanobiotechnology 2025 Jul 8;23(1):492
The role of glucocorticoids in hepatocellular carcinoma through integrated bioinformatics analysis and experimental validation.
Wang A, Yin X, Li S, Fu Y, Jiang T, Fu J
Scientific reports 2025 Jul 25;15(1):27094
Scientific reports 2025 Jul 25;15(1):27094
Single-cell transcriptomics identifies PDGFRA(+) progenitors orchestrating angiogenesis and periodontal tissue regeneration.
Liu J, He J, Zhang Z, Liu L, Cao Y, Zhang X, Cai X, Luo X, Lei X, Zhang N, Wang H, Chen J, Liu P, Tian J, Liu J, Gao Y, Xu H, Ma C, Bai S, Zhang Y, Jin Y, Zheng C, Sui B, Jin F
International journal of oral science 2025 Jul 24;17(1):56
International journal of oral science 2025 Jul 24;17(1):56
Gut microbiota-derived indole-3-acetic acid ameliorates calcium oxalate renal stone formation via AHR/NF‑κB axis.
Jing J, Yan X, Wang L, Zhang Y, Qi W, Xi J, Hao Z
Urolithiasis 2025 Jul 2;53(1):134
Urolithiasis 2025 Jul 2;53(1):134
Single-Cell and Spatial Transcriptomics Reveal a Tumor-Associated Macrophage Subpopulation that Mediates Prostate Cancer Progression and Metastasis.
Mei S, Zhang H, Hirz T, Jeffries NE, Xu Y, Baryawno N, Wu S, Wu CL, Patnaik A, Saylor PJ, Sykes DB, Dahl DM
Molecular cancer research : MCR 2025 Jul 2;23(7):653-665
Molecular cancer research : MCR 2025 Jul 2;23(7):653-665
Identification and verification of oxidative stress-related genes in the diagnosis of osteoporosis.
Liu Z, Yang X, Wang Z, Li Q, Gu H, Meng Q, Zhang Y
Scientific reports 2025 Jul 2;15(1):23222
Scientific reports 2025 Jul 2;15(1):23222
Multiomic identification of senescent stem cell populations critical for osteoarthritis progression and therapy in subchondral bones.
Li PL, Tang J, Li XT, Zhao SR, Xu RX, Zhao ZD, Li ZL, Li ZL, Yin BF, Yu FH, Wu CT, Zhu H
Science advances 2025 Jul 18;11(29):eadu2294
Science advances 2025 Jul 18;11(29):eadu2294
Secreted phosphoprotein 1 promotes the activation of keloid fibroblasts via the CD44/TGF-β1/Smad pathway.
Tu Y, Xiong Y, Liu O, Peng Y
Experimental cell research 2025 Jul 15;450(2):114658
Experimental cell research 2025 Jul 15;450(2):114658
Negative Air Ions Attenuate Nicotine-Induced Vascular Endothelial Dysfunction by Suppressing AP1-Mediated FN1 and SPP1.
Xiao S, Wei T, Xiao M, Shan M, An Z, Li N, Zhou J, Zhao S, Lu X
Antioxidants (Basel, Switzerland) 2025 Jul 14;14(7)
Antioxidants (Basel, Switzerland) 2025 Jul 14;14(7)
Integrated Single-Cell Analysis Dissects Regulatory Mechanisms Underlying Tumor-Associated Macrophage Plasticity in Hepatocellular Carcinoma.
Gu Y, Zhu W, Zhang Z, Shu H, Huang H, Sun X
Genes 2025 Jul 12;16(7)
Genes 2025 Jul 12;16(7)
Apoptotic extracellular vesicles derived from human dental pulp stem cells facilitate periodontal tissue regeneration.
Xia J, Zhang Z, Weng J, Zhu G, Xu Z, Zeng L, Pathak JL, Yu L
BMC oral health 2025 Jul 11;25(1):1150
BMC oral health 2025 Jul 11;25(1):1150
Single-cell transcriptomic analysis of the senescent microenvironment in bone metastasis.
Wang S, Ao L, Lin H, Wei H, Wu Z, Lu S, Liang F, Shen R, Zhang H, Miao T, Shen X, Lin J, Zhong G
Cell proliferation 2025 Jan;58(1):e13743
Cell proliferation 2025 Jan;58(1):e13743
Moderate static magnetic field regulates iron metabolism and salvage bone loss caused by iron accumulation.
Zhen C, Wang S, Yang J, Zhang G, Cai C, Wang J, Wang A, Xu Y, Fang Y, Wei M, Yin D, Luo X, Gong M, Zhang H, Shang P
Journal of orthopaedic translation 2025 Jan;50:144-157
Journal of orthopaedic translation 2025 Jan;50:144-157
NIR-stimulated rGO-HAMC hydrogel enhances fracture healing through regulating B-cell signaling.
Yang HZ, Zhan Y, Liu Y, Guo M, Fan Y, Luo G, Zhao Y, Huang S, Sun T, Li SS, Ye Q, Jin X
Biomaterials advances 2025 Jan;166:214080
Biomaterials advances 2025 Jan;166:214080
Magnesium-Impregnated Membrane Promotes Bone Regeneration in Rat Skull Defect by N-Linked Glycosylation of SPARC via MagT1.
Chen W, Lu H, Yu W, Huang L, Bian M, Wang N, Xiang X, Mo G, Zhang C, Li Y, Jiang L, Zhang J
Advanced healthcare materials 2025 Jan;14(2):e2402705
Advanced healthcare materials 2025 Jan;14(2):e2402705
Naked cuticle homolog 2 controls the differentiation of osteoblasts and osteoclasts and ameliorates bone loss in ovariectomized mice.
Shan L, Liao X, Yang X, Zhu E, Yuan H, Zhou J, Li X, Wang B
Genes & diseases 2025 Jan;12(1):101209
Genes & diseases 2025 Jan;12(1):101209
Tea Polyphenol-Derived Carbon Dots Alleviate Abdominal Aortic Aneurysm Progression by Mitigating Oxidative Stress and Ferroptosis.
Zhang L, Chen S, Ning M, Guo S, Wen D, Wang H, Sun Y, Yang G, Wang Y, Xue S
ACS applied bio materials 2025 Jan 20;8(1):688-703
ACS applied bio materials 2025 Jan 20;8(1):688-703
Dentin tubules as a long-term sustained release carrier to accelerate bone repair by loading FTY720.
Xie J, Huang H, Xu S, Zhou K, Chen X, Fang J, Zhao F
Journal of controlled release : official journal of the Controlled Release Society 2025 Jan 10;377:446-457
Journal of controlled release : official journal of the Controlled Release Society 2025 Jan 10;377:446-457
Shen Qi Wan regulates OPN/CD44/PI3K pathway to improve airway inflammation in COPD: Network pharmacology, bioinformatics, and experimental validation.
Huang J, Zhou X, Xu Y, Yu C, Zhang H, Qiu J, Wei J, Luo Q, Xu Z, Lin Y, Qiu P, Li C
International immunopharmacology 2025 Jan 10;144:113624
International immunopharmacology 2025 Jan 10;144:113624
MSC-EXs inhibits uranium nephrotoxicity by competitively binding key proteins and inhibiting ROS production.
Yang X, Liu J, Yin Y, Yang L, Gao M, Wu Z, Lu B, Luo S, Wang W, Li R
Ecotoxicology and environmental safety 2025 Jan 1;289:117654
Ecotoxicology and environmental safety 2025 Jan 1;289:117654
Single-cell RNA sequencing analysis reveals the dynamic changes in the tumor microenvironment during NMIBC recurrence.
Chen Z, Zhang T, Li W, Hu J, Ou Y, Ye F, Zhang J, Jiang H, Liu S
Apoptosis : an international journal on programmed cell death 2025 Feb;30(1-2):282-296
Apoptosis : an international journal on programmed cell death 2025 Feb;30(1-2):282-296
Doxorubicin and topotecan resistance in ovarian cancer: Gene expression and microenvironment analysis in 2D and 3D models.
Świerczewska M, Nowacka M, Stasiak P, Iżycki D, Sterzyńska K, Płóciennik A, Nowicki M, Januchowski R
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Feb;183:117804
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Feb;183:117804
Synergistic Enhancement of Antibacterial and Osteo-Immunomodulatory Activities of Titanium Implants via Dual-Responsive Multifunctional Surfaces.
Wang Q, Gao Y, Chen Y, Wang X, Pei Q, Zhang T, Wang C, Pan J
Advanced healthcare materials 2025 Feb;14(4):e2404260
Advanced healthcare materials 2025 Feb;14(4):e2404260
SPP1-ITGα5/β1 Accelerates Calcification of Nucleus Pulposus Cells by Inhibiting Mitophagy via Ubiquitin-Dependent PINK1/PARKIN Pathway Blockade.
Gu H, Li Q, Liu Z, Li Y, Liu K, Kong X, Zhang Y, Meng Q, Song K, Xie Q, Gao Y, Cheng L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(7):e2411162
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(7):e2411162
Low-Intensity Pulsed Ultrasound Responsive Scaffold Promotes Intramembranous and Endochondral Ossification via Ultrasonic, Thermal, and Electrical Stimulation.
Jia W, Wang T, Chen F, Liu Z, Hou X, Cao W, Zhao X, Lu B, Hu Y, Dong Y, Zhou J, Zhou Z, Zhan W
ACS nano 2025 Feb 4;19(4):4422-4439
ACS nano 2025 Feb 4;19(4):4422-4439
Regulation of macrophage-mediated osteogenesis by kaempferol liposomes in trauma-induced heterotopic ossification.
Zhang D, Qu X, Chu F, Wang Z, Mou J, Yuan F
International journal of pharmaceutics 2025 Feb 25;671:125226
International journal of pharmaceutics 2025 Feb 25;671:125226
Mechanistic studies of Ca(2+)-induced classical pyroptosis pathway promoting renal adhesion on calcium oxalate kidney stone formation.
Xiang J, Lv M, Luo Y, Ke K, Zhang B, Wang M, Zhang K, Li H
Scientific reports 2025 Feb 24;15(1):6669
Scientific reports 2025 Feb 24;15(1):6669
Cordycepin ameliorates spaceflight-induced osteoporosis by preventing BMSCs oxidative stress and senescence via interacting with PI3K p110α and regulating PI3K/Akt/FOXO3 signalling.
Zhai Y, Zhang Y, Xu K, Wang T, Zhiqun Bian, Qu L, Wu F, Hu Z, Chang X, Li H, Zhang C, Li C, Shi C
Free radical biology & medicine 2025 Feb 16;228:108-125
Free radical biology & medicine 2025 Feb 16;228:108-125
SPP1-mediated crosstalk between macrophage and fibroblasts promotes benign airway stenosis.
Niu F, Sun B, Yu Y, Xu X, Li H, Huang L, Wang Y, Cai Z
Archives of biochemistry and biophysics 2025 Dec;774:110627
Archives of biochemistry and biophysics 2025 Dec;774:110627
Nano MgO loaded thermosensitive HPCH@HA hydrogel accelerates in situ bone repair through osteoimmunomodulation while enhancing angiogenesis and osteogenesis.
Ni F, Chang L, Peng Y, Li D, Wu D, Li K, Zhang X, Jiang X, Shao Z, Chen Y, Wang H
Bioactive materials 2025 Dec;54:248-272
Bioactive materials 2025 Dec;54:248-272
Ceria nanoparticles guard against glucocorticoid induced bone homeostasis imbalance through the promotion of osteogenesis and inhibition of osteoclastogenesis.
Zhang A, Liu Z, Zou L, Yang L, Wu Y, Wang X, Cao D, Liu J, Yang X, Zhang S
Materials today. Bio 2025 Dec;35:102308
Materials today. Bio 2025 Dec;35:102308
High Shear Stress-Induced Endothelial Piezo1 Downregulation Promotes Intracranial Aneurysm Formation via the PDGF-BB/PDGFRβ Paracrine Signaling Pathway.
Lu Z, Li S, Xu F, Tang H, Zhu S, Wang C, Yang X, Huang Q
CNS neuroscience & therapeutics 2025 Dec;31(12):e70715
CNS neuroscience & therapeutics 2025 Dec;31(12):e70715
Cuttlebone inspired "S"-grooved topological structures facilitate osteogenic differentiation through the Rap1-ERK pathway.
Sun Y, Cai Y, Xu S, Zhai N, Wang Z, Qiu Z, Han S, Wei Y, Liu R, Wu H
Biomaterials advances 2025 Dec;177:214431
Biomaterials advances 2025 Dec;177:214431
Lumican from DESC spheroids enhances odontoblastic differentiation of SCAPs.
Zhang Q, Huang S, Liu X, Zhang M, Sun J, Liu M, Nie H, Lei L
Stem cell research & therapy 2025 Dec 7;17(1):27
Stem cell research & therapy 2025 Dec 7;17(1):27
Neutrophil extracellular traps promote bone loss in type 1 diabetes via suppression of the FN1-PI3K/Akt signaling axis.
Liu X, Xiao D, Zhang D, Pan Y, Guo J, Zhang Y, Li S, Tang Q, Jin X, Sun T
International immunopharmacology 2025 Dec 3;166:115629
International immunopharmacology 2025 Dec 3;166:115629
Injectable Nanocomposite Biomaterial for 3D Printing of Personalized Matrices and Their Use in Bioreactors for Bioengineering Advanced Cell Culture Models.
Campodoni E, Mazzoleni A, Montanari M, Vicinelli G, Possetti V, Inforzato A, Martin I, Muraro MG, Sandri M
ACS applied materials & interfaces 2025 Dec 17;17(50):68440-68456
ACS applied materials & interfaces 2025 Dec 17;17(50):68440-68456
Single-cell identification of an endothelial cell proximal SPP1(+) macrophage population defines the metastatic vascular niche in lymph nodes.
Lao Z, Tan R, Maitikuerban M, Xu X, Zhang S, Ma J, Wang D, Liao G, Yang L
Scientific reports 2025 Dec 16;15(1):43896
Scientific reports 2025 Dec 16;15(1):43896
Manganese dioxide coupled metal-organic framework as mitophagy regulator alleviates periodontitis through SIRT1-FOXO3-BNIP3 signaling axis.
Zhu C, Huang K, Li T, Li Y, Jin Y, Li R, Zhu Z, Yang S, Xia L, Fang B
Biomaterials 2025 Aug;319:123179
Biomaterials 2025 Aug;319:123179
Bgh/GelMA/CMCS hydrogel with bone MSC-EVs for lunate defect repair.
Li M, Hu H, Liu L, Tian M, Li X
Nanomedicine (London, England) 2025 Aug;20(15):1835-1850
Nanomedicine (London, England) 2025 Aug;20(15):1835-1850
Vascular Smooth Muscle-Secreted Exosomal X26nt Impedes Atherosclerosis Progression via the c-FOS/XBP1/SOD1 Axis.
Zhang Z, Liu D, Zheng Y, Liu Y, Cheng X, Chang Y, Liang X, Hu X, Gao W
Immunity, inflammation and disease 2025 Aug;13(8):e70251
Immunity, inflammation and disease 2025 Aug;13(8):e70251
Hypoxanthine Promotes Pulmonary Vascular Remodeling and Adenosine Deaminase Is a Therapeutic Target for Pulmonary Hypertension.
Shi JZ, Zhu YJ, Zhang MJ, Yan Y, Zhao LL, Zhang HD, Liu Y, Wu WH, Cheng Z, Qiu CG, Kou JJ, Zhou YF, Pang XB, Chen JW, Xie XM, He YY, Jing ZC
JACC. Basic to translational science 2025 Aug;10(8):101273
JACC. Basic to translational science 2025 Aug;10(8):101273
TCF7L2 regulates GPX4 to resist ferroptosis and enhance osteogenesis in mouse mesenchymal stem cells.
Lei M, Liu B, Wan B, Feng Y, Teng Y, Xi D, Zeng G, Zong S
European journal of medical research 2025 Aug 5;30(1):713
European journal of medical research 2025 Aug 5;30(1):713
M2c Macrophages Mediate YAP1 to Promote Vascularized Bone Regeneration in Distraction Osteogenesis.
Liu H, Liu K, Shang Y, Wei J, He S, Ma C, Xu T, Zhou N, Zhu P, Huang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 15;39(15):e70923
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 15;39(15):e70923
Laboratory investigation of METTL7A driving MSC osteogenic differentiation through YAP1 translation enhancement via eIF4F recruitment.
Cui L, Mai Z, Lu Y, Zheng J, Lin P, Chen X, Zheng Y, Lin Y, Guo B, Zhao X
International endodontic journal 2025 Apr;58(4):587-603
International endodontic journal 2025 Apr;58(4):587-603
Cerium-Containing Mesoporous Bioactive Glass Nanoparticles Reinforced 3D-Printed Bioceramic Scaffolds toward Enhanced Mechanical, Antioxidant, and Osteogenic Activities for Bone Regeneration.
Zhao Z, Chen X, Chen H, Zhang J, Du L, Jiang F, Zheng K
Advanced healthcare materials 2025 Apr;14(9):e2404346
Advanced healthcare materials 2025 Apr;14(9):e2404346
Isovaleroylbinankadsurin A ameliorates atherosclerosis and restenosis by promoting LXRα signaling pathway and inhibiting TGF-β1 and FHL1 signaling pathways.
Shi Y, Liu L, Gong Y, Zhang C, Yang Y, Wang W, Qin L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156451
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156451
Ganoderic Acid A Prevented Osteoporosis by Modulating the PIK3CA/p-Akt/TWIST1 Signaling Pathway.
Zhao J, Fan Y, Li H, Wang C, Fan S, Sun H, Liu M
Food science & nutrition 2025 Apr;13(4):e70177
Food science & nutrition 2025 Apr;13(4):e70177
Exonic CircGUCY1A2 inhibits pulmonary artery smooth muscle cells phenotypic switching via regulating O-glycosylation of COL3A1 in pulmonary hypertension.
Bai J, Gao D, Mei J, Yuan H, Wang X, Zhang L, Ma C, Yu H, Guan X, Liu H, Wang H, Wan K, Zhu D
European journal of pharmacology 2025 Apr 5;992:177328
European journal of pharmacology 2025 Apr 5;992:177328
Cathepsin D inhibits AGEs-induced phenotypic transformation in vascular smooth muscle cells.
He X, Tian S, Bu L, Zhao X, Zheng L, Zhang P, Guo R, Ma M
Scientific reports 2025 Apr 3;15(1):11502
Scientific reports 2025 Apr 3;15(1):11502
USP2-induced upregulation of LEF1 through deubiquitination relieves osteoporosis development by promoting the osteogenic differentiation of bone marrow mesenchymal stem cells.
Zhang Z, Cao J, Xing H, Liu J, Li L, Zhang Y
Journal of orthopaedic surgery and research 2025 Apr 29;20(1):430
Journal of orthopaedic surgery and research 2025 Apr 29;20(1):430
Polydopamine-functionalized acellular fish scale scaffolds for accelerated bone tissue regeneration.
Su S, Wang R, Bai J, Gao S, Zhou R, Zhou F
RSC advances 2025 Apr 28;15(18):13857-13873
RSC advances 2025 Apr 28;15(18):13857-13873
USP22/BRD4 mediated hedgehog pathway activation contributes to airway remodeling in asthma.
Chen H, Liu J, Zhang J, Chen Y, Wang Y, Qiu Y, Hu H, Chai L, Zhang Q, Wang Q, Li M
International immunopharmacology 2025 Apr 24;153:114538
International immunopharmacology 2025 Apr 24;153:114538
Estrogen Inhibits the Phenotypic Switching of Vascular Smooth Muscle Cells through ER-α/CREB in Aortic Dissection.
Pu Y, Zhou Y, Guo T, Chai X, Yang G
ACS omega 2025 Apr 22;10(15):15256-15271
ACS omega 2025 Apr 22;10(15):15256-15271
LncRNA NEAT1 sponges miR-214-3p to promote osteoblast differentiation through regulating the PI3K/AKT/mTOR pathway in aortic valve calcification.
Xu R, Sun Y, Tian F, Zhao M
Scientific reports 2025 Apr 21;15(1):13665
Scientific reports 2025 Apr 21;15(1):13665
Facile Nanocomposite Hydrogel Scaffold with Sustained Drug Release and Osteo-Immunomodulatory Effects to Enhance Bone Regeneration.
Zhao F, Su Y, Liu H, Zhao Y, Zhang L, Zhuge N, Zhao P, Ning Z, Kang Q, Liu D
ACS applied materials & interfaces 2025 Apr 2;17(13):19286-19303
ACS applied materials & interfaces 2025 Apr 2;17(13):19286-19303
MIR155HG suppresses the osteogenic differentiation of bone marrow mesenchymal stem cells through regulating miR-155-5p and DKK1 expression.
Li W, Yang C, Xu J, Ran D, Wang C
Journal of orthopaedic surgery and research 2025 Apr 19;20(1):392
Journal of orthopaedic surgery and research 2025 Apr 19;20(1):392
The sonic hedgehog signaling inhibitor cyclopamine improves pulmonary arterial hypertension via regulating the bone morphogenetic protein receptor 2 pathway.
Jin Y, Mao F, Wang X, Zhang J, Gao Y, Fan Y
Scientific reports 2025 Apr 11;15(1):12512
Scientific reports 2025 Apr 11;15(1):12512
Extracellular Vesicles Derived from H(2)O(2)-Stimulated Adipose-Derived Stem Cells Alleviate Senescence in Diabetic Bone Marrow Mesenchymal Stem Cells and Restore Their Osteogenic Capacity.
Li Y, Yue G, Yu S, Liu Z, Cao Y, Wang X
Drug design, development and therapy 2024;18:2103-2124
Drug design, development and therapy 2024;18:2103-2124
Transcriptomic Insights into Hub Genes, Immune Infiltration, and Candidate Drugs in Erosive Esophagitis.
Zhao Y, Chen X, Huang Y, Zhang Z, Wang K, Zou D, Ma T
Journal of inflammation research 2024;17:7745-7760
Journal of inflammation research 2024;17:7745-7760
Multifunctional injectable hydrogel system as a mild photothermal-assisted therapeutic platform for programmed regulation of inflammation and osteo-microenvironment for enhanced healing of diabetic bone defects in situ.
Zhu Y, Liu H, Wu P, Chen Y, Deng Z, Cai L, Wu M
Theranostics 2024;14(18):7140-7198
Theranostics 2024;14(18):7140-7198
Multifunctionally disordered TiO(2) nanoneedles prevent periprosthetic infection and enhance osteointegration by killing bacteria and modulating the osteoimmune microenvironment.
Chen Y, Zhou L, Guan M, Jin S, Tan P, Fu X, Zhou Z
Theranostics 2024;14(15):6016-6035
Theranostics 2024;14(15):6016-6035
Integrated analysis of colorectal cancer metastasis identifies characteristics of tumor cell during metastasis.
Fu H, Lu X, Ji T, Wang L, Wang G, Wang L, Wang Z
Gastroenterology report 2024;12:goae055
Gastroenterology report 2024;12:goae055
A submicron forest-like silicon surface promotes bone regeneration by regulating macrophage polarization.
Sun G, Shu T, Ma S, Li M, Qu Z, Li A
Frontiers in bioengineering and biotechnology 2024;12:1356158
Frontiers in bioengineering and biotechnology 2024;12:1356158
GSDMB involvement in the pathogenesis of abdominal aortic aneurysm through regulation of macrophage non-canonical pyroptosis.
Xie X, Shen X, Liu Y, Zuo Y, Wang S, Zhou Y, Li X, Wang K, Li B, Wang Z
Archives of biochemistry and biophysics 2024 Sep;759:110102
Archives of biochemistry and biophysics 2024 Sep;759:110102
Endogenous hydrogen sulfide accelerated trauma-induced heterotopic ossification through the Ca(2+)/ERK pathway-enhanced aberrant osteogenic activity.
Yuan Z, Li J, He K, Sun Z, Luo G, Liu H, Dong J, Zhou C, Cui H, Fan C
Redox biology 2024 Sep;75:103265
Redox biology 2024 Sep;75:103265
KIAA0753 enhances osteoblast differentiation suppressed by diabetes.
Li M, Wang Y, Wu X, Chen Q, Huang J, Zhu H, Yang S, Wang J, Li LT, Liu X, Fu K, Song F, Wang C
Journal of cellular and molecular medicine 2024 Sep;28(17):e70035
Journal of cellular and molecular medicine 2024 Sep;28(17):e70035
Thirdhand smoke exposure promotes gastric tumor development in mouse and human.
Jiang C, Chen L, Ye C, Schick SF, Jacob P 3rd, Zhuang Y, Inman JL, Chen C, Gundel LA, Chang H, Snijders AM, Zou X, Mao JH, Hang B, Wang P
Environment international 2024 Sep;191:108986
Environment international 2024 Sep;191:108986
Osteoclast-derived exosomes influence osteoblast differentiation in osteoporosis progression via the lncRNA AW011738/ miR-24-2-5p/ TREM1 axis.
Liu J, Wang B, Chen H, Yu X, Cao X, Zhang H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117231
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117231
Metabolic Control During Macrophage Polarization by a Citrate-Functionalized Scaffold for Maintaining Bone Homeostasis.
Wu X, Xia Y, Dai H, Hong C, Zhao Y, Wei W, Zheng D
Advanced healthcare materials 2024 Sep;13(22):e2400770
Advanced healthcare materials 2024 Sep;13(22):e2400770
Osteopontin deficiency promotes cartilaginous endplate degeneration by enhancing the NF-κB signaling to recruit macrophages and activate the NLRP3 inflammasome.
Wang Y, Zhang W, Yang Y, Qin J, Wang R, Wang S, Fu W, Niu Q, Wang Y, Li C, Li H, Zhou Y, Liu M
Bone research 2024 Sep 6;12(1):53
Bone research 2024 Sep 6;12(1):53
The Involvement of Endoplasmic Reticulum Stress during the Interaction between Calcium Oxalate Crystals and Renal Tubular Epithelial Cells.
Hong SY, Miao LT, Qin BL
Biology 2024 Sep 27;13(10)
Biology 2024 Sep 27;13(10)
Nitrogen-containing bisphosphonate induces enhancement of OPG expression and inhibition of RANKL expression via inhibition of farnesyl pyrophosphate synthase to inhibit the osteogenic differentiation and calcification in vascular smooth muscle cells.
Xu W, Gong L, Tang W, Lu G
BMC cardiovascular disorders 2024 Sep 17;24(1):494
BMC cardiovascular disorders 2024 Sep 17;24(1):494
TRIM16 mitigates impaired osteogenic differentiation and antioxidant response in D-galactose-induced senescent osteoblasts.
Li K, Huang K, Lu Q, Geng W, Jiang D, Guo A
European journal of pharmacology 2024 Sep 15;979:176849
European journal of pharmacology 2024 Sep 15;979:176849
SPP1 promotes the polarization of M2 macrophages through the Jak2/Stat3 signaling pathway and accelerates the progression of idiopathic pulmonary fibrosis.
Yang X, Liu Z, Zhou J, Guo J, Han T, Liu Y, Li Y, Bai Y, Xing Y, Wu J, Hu D
International journal of molecular medicine 2024 Oct;54(4)
International journal of molecular medicine 2024 Oct;54(4)
Renal denervation alleviates vascular remodeling in spontaneously hypertensive rats by regulating perivascular adipose tissue.
Jiang T, Wei Y, Xu R, Jin Y, Song T, Wang H, Chen W, Tian H, Xu L, Zhao Y, Fu Y
Hypertension research : official journal of the Japanese Society of Hypertension 2024 Oct;47(10):2760-2772
Hypertension research : official journal of the Japanese Society of Hypertension 2024 Oct;47(10):2760-2772
The resistance to anoikis, mediated by Spp1, and the evasion of immune surveillance facilitate the invasion and metastasis of hepatocellular carcinoma.
Zhang Z, Chen X, Li Y, Zhang F, Quan Z, Wang Z, Yang Y, Si W, Xiong Y, Ju J, Bian Y, Sun S
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1564-1583
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1564-1583
LTF ameliorates cartilage endplate degeneration by suppressing calcification, senescence and matrix degradation through the JAK2/STAT3 pathway.
Li T, Liu Y, Cao J, Pan C, Ding R, Zhao J, Liu J, He D, Jia J, Cheng X
Journal of cellular and molecular medicine 2024 Oct;28(19):e18267
Journal of cellular and molecular medicine 2024 Oct;28(19):e18267
Multifunctional human serum albumin-crosslinked and self-assembling nanoparticles for therapy of periodontitis by anti-oxidation, anti-inflammation and osteogenesis.
Cao B, Da X, Wu W, Xie J, Li X, Wang X, Xu H, Gao J, Yang H, Su J
Materials today. Bio 2024 Oct;28:101163
Materials today. Bio 2024 Oct;28:101163
Construction of competitive endogenous RNA network and identification of potential regulatory axis in vascular calcification.
Xu T, Li Y, Cheng M, Jin J, Zhang S, Bai Y, Xu J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Oct 31;38(20):e70114
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Oct 31;38(20):e70114
Deletion of Kcnj16 altered transcriptomic and metabolomic profiles of Dahl salt-sensitive rats.
Xu B, Dissanayake LV, Levchenko V, Zietara A, Kravtsova O, Staruschenko A
iScience 2024 Oct 18;27(10):110901
iScience 2024 Oct 18;27(10):110901
From ROS scavenging to boosted osseointegration: cerium-containing mesoporous bioactive glass nanoparticles functionalized implants in diabetes.
Jiang X, Wei J, Ding X, Zheng K, Zhou T, Shi J, Lai H, Qian S, Zhang X
Journal of nanobiotechnology 2024 Oct 18;22(1):639
Journal of nanobiotechnology 2024 Oct 18;22(1):639
Single-cell spatiotemporal analysis of the lungs reveals Slamf9(+) macrophages involved in viral clearance and inflammation resolution.
Cong B, Dong X, Yang Z, Yu P, Chai Y, Liu J, Zhang M, Zang Y, Kang J, Feng Y, Liu Y, Feng W, Wang D, Deng W, Li F, Song Z, Wang Z, Chen X, Qin H, Yu Q, Li Z, Liu S, Xu X, Zhong N, Ren X, Qin C, Liu L, Wang J, Cao X
Cell discovery 2024 Oct 16;10(1):104
Cell discovery 2024 Oct 16;10(1):104
CD8+ T cell associated scoring model helps prognostic diagnosis and immunotherapy selection in patients with colon adenocarcinoma.
Zhao Z, Chen M, Sun K, Gu X
Heliyon 2024 Oct 15;10(19):e37998
Heliyon 2024 Oct 15;10(19):e37998
The Altered Proteomic Landscape in Renal Tubular Epithelial Cells under High Oxalate Stimulation.
Hong SY, Qin BL
Biology 2024 Oct 11;13(10)
Biology 2024 Oct 11;13(10)
Early growth response 1 exacerbates thoracic aortic aneurysm and dissection of mice by inducing the phenotypic switching of vascular smooth muscle cell through the activation of Krüppel-like factor 5.
Han X, Xu S, Hu K, Yu Y, Wang X, Qu C, Yang B, Liu X
Acta physiologica (Oxford, England) 2024 Nov;240(11):e14237
Acta physiologica (Oxford, England) 2024 Nov;240(11):e14237
The pivotal role of osteopontin in UV-induced skin inflammation in a mouse model.
Kim H, Shin CY, Park CH, Lee DH, Lee SH, Chung JH
Open biology 2024 Nov;14(11):230397
Open biology 2024 Nov;14(11):230397
Single-cell RNA sequencing reveals immune microenvironment niche transitions during the invasive and metastatic processes of ground-glass nodules and part-solid nodules in lung adenocarcinoma.
Ren YF, Ma Q, Zeng X, Huang CX, Ren JL, Li F, Tong JJ, He JW, Zhong Y, Tan SY, Jiang H, Zhang LF, Lai HZ, Xiao P, Zhuang X, Wu P, You LT, Shi W, Fu X, Zheng C, You FM
Molecular cancer 2024 Nov 23;23(1):263
Molecular cancer 2024 Nov 23;23(1):263
HIF-1α knockdown attenuates phenotypic transformation and oxidative stress induced by high salt in human aortic vascular smooth muscle cells.
Deng W, Huang S, Yu L, Gao B, Pan Y, Wang X, Li L
Scientific reports 2024 Nov 15;14(1):28100
Scientific reports 2024 Nov 15;14(1):28100
One-Step Gas Foaming Strategy for Constructing Strontium Nanoparticle Decorated 3D Scaffolds: a New Platform for Repairing Critical Bone Defects.
Chen Y, Li Y, Wang X, Mo X, Chen Y, Deng Z, Ye X, Yu J
ACS applied materials & interfaces 2024 Nov 13;16(45):61664-61678
ACS applied materials & interfaces 2024 Nov 13;16(45):61664-61678
Bioactive peptide relieves glucocorticoid-induced osteoporosis by giant macrocyclic encapsulation.
Shang Y, Zhu Q, Ding J, Zhao L, Zhang F, Lu J, Feng Y, Wang J, Liu Z, Kuang M, Li C
Journal of controlled release : official journal of the Controlled Release Society 2024 May;369:75-87
Journal of controlled release : official journal of the Controlled Release Society 2024 May;369:75-87
Urchin-like multiscale structured fluorinated hydroxyapatite as versatile filler for caries restoration dental resin composites.
Zhang S, Wang X, Yin S, Wang J, Chen H, Jiang X
Bioactive materials 2024 May;35:477-494
Bioactive materials 2024 May;35:477-494
CNPY2 governs PDGF‑BB‑treated vascular smooth muscle cell proliferation, migration and phenotypic transformation via the Akt/mTOR/GSK‑3β signaling pathway.
Sun H, Wang X, Ma L, Li X, Jin W, Yang Y
Experimental and therapeutic medicine 2024 May;27(5):197
Experimental and therapeutic medicine 2024 May;27(5):197
Asprosin aggravates atherosclerosis via regulating the phenotype transformation of vascular smooth muscle cells.
Zhao Y, Wang Z, Chen Y, Feng M, Liu X, Chen H, Wang N, Wang Z, Cao S, Ren J, Liu X, Zhao Y, Zhang Y
International journal of biological macromolecules 2024 May;268(Pt 2):131868
International journal of biological macromolecules 2024 May;268(Pt 2):131868
Multifunctional tannic acid-based nanocomposite methacrylated silk fibroin hydrogel with the ability to scavenge reactive oxygen species and reduce inflammation for bone regeneration.
Wang R, He X, Su S, Bai J, Liu H, Zhou F
International journal of biological macromolecules 2024 May;266(Pt 2):131357
International journal of biological macromolecules 2024 May;266(Pt 2):131357
Injectable, anti-collapse, adhesive, plastic and bioactive bone graft substitute promotes bone regeneration by moderating oxidative stress in osteoporotic bone defect.
Huang L, Zhang S, Bian M, Xiang X, Xiao L, Wang J, Lu S, Chen W, Zhang C, Mo G, Jiang L, Li Y, Zhang J
Acta biomaterialia 2024 May;180:82-103
Acta biomaterialia 2024 May;180:82-103
An integrated multi-omics analysis reveals osteokines involved in global regulation.
Liang W, Wei T, Hu L, Chen M, Tong L, Zhou W, Duan X, Zhao X, Zhou W, Jiang Q, Xiao G, Zou W, Chen D, Zou Z, Bai X
Cell metabolism 2024 May 7;36(5):1144-1163.e7
Cell metabolism 2024 May 7;36(5):1144-1163.e7
Fibrous periosteum repairs bone fracture and maintains the healed bone throughout mouse adulthood.
Liu YL, Tang XT, Shu HS, Zou W, Zhou BO
Developmental cell 2024 May 6;59(9):1192-1209.e6
Developmental cell 2024 May 6;59(9):1192-1209.e6
Activation of CaMKII/HDAC4 by SDF1 contributes to pulmonary arterial hypertension via stabilization Runx2.
Chen Y, Liu J, Zhang Q, Chai L, Chen H, Li D, Wang Y, Qiu Y, Shen N, Zhang J, Wang Q, Wang J, Xie X, Li S, Li M
European journal of pharmacology 2024 May 5;970:176483
European journal of pharmacology 2024 May 5;970:176483
Carbonylation of Runx2 at K176 by 4-Hydroxynonenal Accelerates Vascular Calcification.
Zhai X, Cao S, Wang J, Qiao B, Liu X, Hua R, Zhao M, Sun S, Han Y, Wu S, Pang J, Yuan Q, Wang B, Xu F, Wei S, Chen Y
Circulation 2024 May 28;149(22):1752-1769
Circulation 2024 May 28;149(22):1752-1769
Spatiotemporal ATF3 Expression Determines VSMC Fate in Abdominal Aortic Aneurysm.
Wen Y, Liu Y, Li Q, Tan J, Fu X, Liang Y, Tuo Y, Liu L, Zhou X, LiuFu D, Fan X, Chen C, Chen Z, Wang Z, Fan S, Liu R, Pan L, Zhang Y, Tang WH
Circulation research 2024 May 24;134(11):1495-1511
Circulation research 2024 May 24;134(11):1495-1511
CRYAB suppresses ferroptosis and promotes osteogenic differentiation of human bone marrow stem cells via binding and stabilizing FTH1.
Tian B, Li X, Li W, Shi Z, He X, Wang S, Zhu X, Shi N, Li Y, Wan P, Zhu C
Aging 2024 May 22;16(10):8965-8979
Aging 2024 May 22;16(10):8965-8979
Targeting osteopontin alleviates endometriosis and inflammation by inhibiting the RhoA/ROS axis and achieves non-invasive in vitro detection via menstrual blood.
Wang H, Wang B, Wu M, Lu J, Duan P
Human reproduction (Oxford, England) 2024 May 2;39(5):1057-1071
Human reproduction (Oxford, England) 2024 May 2;39(5):1057-1071
Osteopontin-driven partial epithelial-mesenchymal transition governs the development of middle ear cholesteatoma.
Zeng L, Xie L, Hu J, He C, Liu A, Lu X, Zhou W
Cell cycle (Georgetown, Tex.) 2024 Mar;23(5):537-554
Cell cycle (Georgetown, Tex.) 2024 Mar;23(5):537-554
Murine double minute 2-mediated estrogen receptor 1 degradation activates macrophage migration inhibitory factor to promote vascular smooth muscle cell dedifferentiation and oxidative stress during thoracic aortic aneurysm progression.
Liu T, Zhang T, Guo C, Liang X, Wang P, Zheng B
Biochimica et biophysica acta. Molecular cell research 2024 Mar;1871(3):119661
Biochimica et biophysica acta. Molecular cell research 2024 Mar;1871(3):119661
Identification of SLC2A1 as a predictive biomarker for survival and response to immunotherapy in lung squamous cell carcinoma.
Hao B, Dong H, Xiong R, Song C, Xu C, Li N, Geng Q
Computers in biology and medicine 2024 Mar;171:108183
Computers in biology and medicine 2024 Mar;171:108183
Mechanism of Porphyra Yezoensis Polysaccharides in Inhibiting Hyperoxalate-Induced Renal Injury and Crystal Deposition.
Deng JW, Li CY, Huang YP, Liu WF, Zhang Q, Long J, Wu WQ, Huang LH, Zeng GH, Sun XY
Journal of agricultural and food chemistry 2024 Mar 27;72(12):6372-6388
Journal of agricultural and food chemistry 2024 Mar 27;72(12):6372-6388
Hypermethylation of Bmp2 and Fgfr2 Promoter Regions in Bone Marrow Mesenchymal Stem Cells Leads to Bone Loss in Prematurely Aged Mice.
Wang Y, Sun L, Kan T, Xue W, Wang H, Xu P, Zhang L, Yan M, Li H, Yu Z
Aging and disease 2024 Mar 24;16(2):1149-1168
Aging and disease 2024 Mar 24;16(2):1149-1168
Single-cell RNA sequencing reveals epithelial cells driving brain metastasis in lung adenocarcinoma.
Wu Y, Yang F, Luo S, Li X, Gu Z, Fan R, Cao Y, Wang L, Song X
iScience 2024 Mar 15;27(3):109258
iScience 2024 Mar 15;27(3):109258
Resolvin D1 attenuates Ang II-induced hypertension in mice by inhibiting the proliferation, migration and phenotypic transformation of vascular smooth muscle cells by blocking the RhoA/mitogen-activated protein kinase pathway.
Wei C, Zhang J, Peng S, Liu J, Xu Y, Zhao M, Xu S, Pan W, Yin Z, Zheng Z, Qin JJ, Wan J, Wang M
Journal of hypertension 2024 Mar 1;42(3):420-431
Journal of hypertension 2024 Mar 1;42(3):420-431
HOXB9 promotes osteosarcoma cell survival and malignancy under glucose starvation via upregulating SPP1 expression.
Han J, Ji R, Zheng S, Xia X, Du W, He H, Han C, Zhao W, Li X, Wang Y, Zhang L
Biochemical pharmacology 2024 Jun;224:116208
Biochemical pharmacology 2024 Jun;224:116208
Integrated bioinformatics analysis identified leucine rich repeat containing 15 and secreted phosphoprotein 1 as hub genes for calcific aortic valve disease and osteoarthritis.
Gong S, Xiang K, Chen L, Zhuang H, Song Y, Chen J
IET systems biology 2024 Jun;18(3):77-91
IET systems biology 2024 Jun;18(3):77-91
Targeting deubiquitinase OTUB1 protects vascular smooth muscle cells in atherosclerosis by modulating PDGFRβ.
Xu F, Chen H, Zhou C, Zang T, Wang R, Shen S, Li C, Yu Y, Pei Z, Shen L, Qian J, Ge J
Frontiers of medicine 2024 Jun;18(3):465-483
Frontiers of medicine 2024 Jun;18(3):465-483
Elevated SLC1A5 associated with poor prognosis and therapeutic resistance to transarterial chemoembolization in hepatocellular carcinoma.
Zhang G, Xiao Y, Tan J, Liu H, Fan W, Li J
Journal of translational medicine 2024 Jun 6;22(1):543
Journal of translational medicine 2024 Jun 6;22(1):543
Iron deficiency affects oxygen transport and activates HIF1 signaling pathway to regulate phenotypic transformation of VSMC in aortic dissection.
Chen Y, Li X, Wang Z, Yuan S, Shen X, Xie X, Xing K, Zhu Q
Molecular medicine (Cambridge, Mass.) 2024 Jun 17;30(1):90
Molecular medicine (Cambridge, Mass.) 2024 Jun 17;30(1):90
CircFgfr2 promotes osteogenic differentiation of rat dental follicle cells by targeting the miR-133a-3p/DLX3 signaling pathway.
Xu C, Xu Z, Li G, Li J, Ye L, Ning Y, Du Y
Heliyon 2024 Jun 15;10(11):e32498
Heliyon 2024 Jun 15;10(11):e32498
The nano-artificial periosteum made of PCL/MgO/AS-IV enhances MC3T3-E1 cell osteogenic differentiation and promotes bone defect repair via the EphB4/EphrinB2 signaling pathway.
Wang W, Sun DF, Cui HX, Zhang WL
Heliyon 2024 Jun 15;10(11):e32036
Heliyon 2024 Jun 15;10(11):e32036
An Immunohistochemical Analysis of Osteopontin and S100 Calcium-binding Protein P is Useful for Subclassifying Large- and Small-duct Type Intrahepatic Cholangiocarcinomas.
Yoshizawa T, Uehara T, Iwaya M, Nakajima T, Shimizu A, Kubota K, Notake T, Kitagawa N, Masuo H, Sakai H, Hayashi H, Tomida H, Yamazaki S, Hirano S, Ota H, Soejima Y
The American journal of surgical pathology 2024 Jun 1;48(6):751-760
The American journal of surgical pathology 2024 Jun 1;48(6):751-760
FOXO1 regulates RUNX2 ubiquitination through SMURF2 in calcific aortic valve disease.
Jiang C, Yao D, Liu Z, Zheng Y, Chen M, Yim WY, Zheng Q, Zhang T, Fan L, Fan Z, Geng B, Tian R, Zhou T, Qiao W, Shi J, Li F, Xu L, Huang Y, Dong N
Redox biology 2024 Jul;73:103215
Redox biology 2024 Jul;73:103215
Alginate-containing 3D-printed hydrogel scaffolds incorporated with strontium promotes vascularization and bone regeneration.
Miao A, Li Q, Tang G, Lu Q
International journal of biological macromolecules 2024 Jul;273(Pt 1):133038
International journal of biological macromolecules 2024 Jul;273(Pt 1):133038
NOX4 and its association with myeloperoxidase and osteopontin in regulating endochondral ossification.
Ko K, Choi S, Jo M, Kim C, Boonpraman N, Youm J, Yi SS
Journal of veterinary science 2024 Jul;25(4):e49
Journal of veterinary science 2024 Jul;25(4):e49
SPP1 could be an immunological and prognostic biomarker: From pan-cancer comprehensive analysis to osteosarcoma validation.
Zhang Z, Liu B, Lin Z, Mei L, Chen R, Li Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 31;38(14):e23783
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 31;38(14):e23783
Silencing SPP1 in M2 macrophages inhibits the progression of castration-resistant prostate cancer via the MMP9/TGFβ1 axis.
Chen S, Deng B, Zhao F, You H, Liu Y, Xie L, Song G, Zhou Z, Huang G, Shen W
Translational andrology and urology 2024 Jul 31;13(7):1239-1255
Translational andrology and urology 2024 Jul 31;13(7):1239-1255
A nanozyme-functionalized bilayer hydrogel scaffold for modulating the inflammatory microenvironment to promote osteochondral regeneration.
Hu C, Huang R, Xia J, Hu X, Xie D, Jin Y, Qi W, Zhao C, Hu Z
Journal of nanobiotechnology 2024 Jul 28;22(1):445
Journal of nanobiotechnology 2024 Jul 28;22(1):445
Endothelial progenitor cells control remodeling of uterine spiral arteries for the establishment of utero-placental circulation.
Tan B, Lin L, Yuan Y, Long Y, Kang Y, Huang B, Huang LF, Li JH, Tong C, Qi HB
Developmental cell 2024 Jul 22;59(14):1842-1859.e12
Developmental cell 2024 Jul 22;59(14):1842-1859.e12
Single-cell transcriptomic insights into chemotherapy-induced remodeling of the osteosarcoma tumor microenvironment.
Zheng X, Wu W, Zhao Z, Zhang X, Yu S
Journal of cancer research and clinical oncology 2024 Jul 20;150(7):356
Journal of cancer research and clinical oncology 2024 Jul 20;150(7):356
CircTOP1 targeted regulation of PTBP1 expression promotes the progression of coronary artery calcification.
Hu H, Shen S, Wu J, Ma L
Experimental cell research 2024 Jul 15;440(2):114147
Experimental cell research 2024 Jul 15;440(2):114147
Single-Cell RNA Transcriptome of the Human Endometrium Reveals Epithelial Characterizations Associated with Recurrent Implantation Failure.
Zhang H, Zhang C, Zhang S
Advanced biology 2024 Jan;8(1):e2300110
Advanced biology 2024 Jan;8(1):e2300110
KLF2/PPARγ axis contributes to trauma-induced heterotopic ossification by regulating mitochondrial dysfunction.
Sun Z, Liu H, Hu Y, Luo G, Yuan Z, Liu W, Tu B, Ruan H, Li J, Fan C
Cell proliferation 2024 Jan;57(1):e13521
Cell proliferation 2024 Jan;57(1):e13521
Myeloid-derived growth factor suppresses VSMC dedifferentiation and attenuates postinjury neointimal formation in rats by activating S1PR2 and its downstream signaling.
Yang S, Li HW, Tian JY, Wang ZK, Chen Y, Zhan TT, Ma CY, Feng M, Cao SF, Zhao Y, Li X, Ren J, Liu Q, Jin LY, Wang ZQ, Jiang WY, Zhao YX, Zhang Y, Liu X
Acta pharmacologica Sinica 2024 Jan;45(1):98-111
Acta pharmacologica Sinica 2024 Jan;45(1):98-111
Isoliquiritin treatment of osteoporosis by promoting osteogenic differentiation and autophagy of bone marrow mesenchymal stem cells.
Su Z, Chen D, Huang J, Liang Z, Ren W, Zhang Z, Jiang Q, Luo T, Guo L
Phytotherapy research : PTR 2024 Jan;38(1):214-230
Phytotherapy research : PTR 2024 Jan;38(1):214-230
3D-printed tri-element-doped hydroxyapatite/ polycaprolactone composite scaffolds with antibacterial potential for osteosarcoma therapy and bone regeneration.
Huang H, Qiang L, Fan M, Liu Y, Yang A, Chang D, Li J, Sun T, Wang Y, Guo R, Zhuang H, Li X, Guo T, Wang J, Tan H, Zheng P, Weng J
Bioactive materials 2024 Jan;31:18-37
Bioactive materials 2024 Jan;31:18-37
Carp scales derived double cross-linking hydrogels achieve collagen peptides sustained-released for bone regeneration.
Zheng F, Ju M, Lü Y, Hua Y, Yao W, Wu H, Zhao M, Han S, Wei Y, Liu R
International journal of biological macromolecules 2024 Jan;255:128276
International journal of biological macromolecules 2024 Jan;255:128276
A novel lncRNA GM15416 regulates osteoblast apoptosis and differentiation through the c-Fos/Fas axis and mitigates osteoporosis.
Zhao D, He J, Zhao X, Sheng X, Feng Z, Wang X, Zhang C, Wang S, Geng B, Xia Y
International journal of biological macromolecules 2024 Jan;254(Pt 2):127824
International journal of biological macromolecules 2024 Jan;254(Pt 2):127824
AT1R autoantibody promotes phenotypic transition of smooth muscle cells by activating AT1R-OAS2.
Zhang X, Li B, Yan Y, Sun F, Zhang S, Wang M, Liu H
Biochemical pharmacology 2024 Jan;219:115977
Biochemical pharmacology 2024 Jan;219:115977
S-adenosylmethionine attenuates angiotensin II-induced aortic dissection formation by inhibiting vascular smooth muscle cell phenotypic switch and autophagy.
Shen X, Xie X, Wu Q, Shi F, Chen Y, Yuan S, Xing K, Li X, Zhu Q, Li B, Wang Z
Biochemical pharmacology 2024 Jan;219:115967
Biochemical pharmacology 2024 Jan;219:115967
Regulation of the immune microenvironment by pioglitazone-loaded polylactic glycolic acid nanosphere composite scaffolds to promote vascularization and bone regeneration.
Fan S, Tan Y, Yuan X, Liu C, Wu X, Dai T, Ni S, Wang J, Weng Y, Zhao H
Journal of tissue engineering 2024 Jan-Dec;15:20417314241231452
Journal of tissue engineering 2024 Jan-Dec;15:20417314241231452
Nanoscaled Titanium Oxide Layer Provokes Quick Osseointegration on 3D-Printed Dental Implants: A Domino Effect Induced by Hydrophilic Surface.
Shu T, Wang X, Li M, Ma S, Cao J, Sun G, Lai T, Liu S, Li A, Qu Z, Pei D
ACS nano 2024 Jan 9;18(1):783-797
ACS nano 2024 Jan 9;18(1):783-797
Single-cell profiling of the microenvironment in human bone metastatic renal cell carcinoma.
Ma F, Wang S, Xu L, Huang W, Shi G, Sun Z, Cai W, Wu Z, Huang Y, Meng J, Sun Y, Fang M, Cheng M, Ji Y, Hu T, Zhang Y, Gu B, Zhang J, Song S, Sun Y, Yan W
Communications biology 2024 Jan 12;7(1):91
Communications biology 2024 Jan 12;7(1):91
PRMT3 methylates HIF-1α to enhance the vascular calcification induced by chronic kidney disease.
Zhou G, Zhang C, Peng H, Su X, Huang Q, Zhao Z, Zhao G
Molecular medicine (Cambridge, Mass.) 2024 Jan 10;30(1):8
Molecular medicine (Cambridge, Mass.) 2024 Jan 10;30(1):8
Alamandine attenuates ovariectomy-induced osteoporosis by promoting osteogenic differentiation via AMPK/eNOS axis.
Luo W, Yao C, Sun J, Zhang B, Chen H, Miao J, Zhang Y
BMC musculoskeletal disorders 2024 Jan 10;25(1):45
BMC musculoskeletal disorders 2024 Jan 10;25(1):45
Nerve growth factor promote osteogenic differentiation of dental pulp stem cells through MEK/ERK signalling pathways.
Cheng C, Tang S, Cui S, Yang T, Li L, Zhai M, Wei F, Ding G
Journal of cellular and molecular medicine 2024 Feb;28(4):e18143
Journal of cellular and molecular medicine 2024 Feb;28(4):e18143
Biomimetic cryogel promotes the repair of osteoporotic bone defects through altering the ROS niche via down-regulating the ROMO1.
Liu H, Pan W, Liu H, Xie D, Liao L
International journal of biological macromolecules 2024 Feb;257(Pt 1):128481
International journal of biological macromolecules 2024 Feb;257(Pt 1):128481
A multifunctional quercetin/polycaprolactone electrospun fibrous membrane for periodontal bone regeneration.
Hu Y, Fu Z, Yang S, Zhou Y, Zhu H, Zhu Y, Zhou J, Lin K, Xu Y
Materials today. Bio 2024 Feb;24:100906
Materials today. Bio 2024 Feb;24:100906
Coenzyme Q10 Protects Against Hyperlipidemia-Induced Osteoporosis by Improving Mitochondrial Function via Modulating miR-130b-3p/PGC-1α Pathway.
Meng M, Wang J, Wang C, Zhao J, Wang H, Zhang Y, Sun H, Liu M
Calcified tissue international 2024 Feb;114(2):182-199
Calcified tissue international 2024 Feb;114(2):182-199
Three Birds, One Stone: An Osteo-Microenvironment Stage-Regulative Scaffold for Bone Defect Repair through Modulating Early Osteo-Immunomodulation, Middle Neovascularization, and Later Osteogenesis.
Yuan Y, Xu Y, Mao Y, Liu H, Ou M, Lin Z, Zhao R, Long H, Cheng L, Sun B, Zhao S, Zeng M, Lu B, Lu H, Zhu Y, Chen C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(6):e2306428
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(6):e2306428
UPP1 promotes lung adenocarcinoma progression through the induction of an immunosuppressive microenvironment.
Li Y, Jiang M, Aye L, Luo L, Zhang Y, Xu F, Wei Y, Peng D, He X, Gu J, Yu X, Li G, Ge D, Lu C
Nature communications 2024 Feb 8;15(1):1200
Nature communications 2024 Feb 8;15(1):1200
HDAC2 counteracts vascular calcification by activating autophagy in chronic kidney disease.
Zhou G, Liu P, Zhang C, Huang Q, Zhao Z, Wu S, Li D, Liu H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Feb 29;38(4):e23470
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Feb 29;38(4):e23470
Retrospective identification of cell-intrinsic factors that mark pluripotency potential in rare somatic cells.
Jain N, Goyal Y, Dunagin MC, Cote CJ, Mellis IA, Emert B, Jiang CL, Dardani IP, Reffsin S, Arnett M, Yang W, Raj A
Cell systems 2024 Feb 21;15(2):109-133.e10
Cell systems 2024 Feb 21;15(2):109-133.e10
PMAIP1, a novel diagnostic and potential therapeutic biomarker in osteoporosis.
Li T, Yuan J, Xu P, Jia J, Zhao J, Zhang J, Ding R, Zhao X, He D, Wu T, Cheng X
Aging 2024 Feb 16;16(4):3694-3715
Aging 2024 Feb 16;16(4):3694-3715
Dual effect of vitamin D(3) on breast cancer-associated fibroblasts.
Łabędź N, Anisiewicz A, Stachowicz-Suhs M, Banach J, Kłopotowska D, Maciejczyk A, Gazińska P, Piotrowska A, Dzięgiel P, Matkowski R, Wietrzyk J
BMC cancer 2024 Feb 15;24(1):209
BMC cancer 2024 Feb 15;24(1):209
Calcitriol promotes M2 polarization of tumor-associated macrophages in 4T1 mouse mammary gland cancer via the induction of proinflammatory cytokines.
Stachowicz-Suhs M, Łabędź N, Anisiewicz A, Banach J, Kłopotowska D, Milczarek M, Piotrowska A, Dzięgiel P, Maciejczyk A, Matkowski R, Wietrzyk J
Scientific reports 2024 Feb 15;14(1):3778
Scientific reports 2024 Feb 15;14(1):3778
CRP inhibits the osteoblastic differentiation of OPCs via the up-regulation of primary cilia and repression of the Hedgehog signaling pathway.
Xu J, Wu X, Zhu H, Zhu Y, Du K, Deng X, Wang C
Medical oncology (Northwood, London, England) 2024 Feb 12;41(3):72
Medical oncology (Northwood, London, England) 2024 Feb 12;41(3):72
Self-Healing Micro Arc Oxidation and Dicalcium Phosphate Dihydrate Double-Passivated Coating on Magnesium Membrane for Enhanced Bone Integration Repair.
Wu J, Shen Y, Wang P, Guo Z, Bai J, Wang X, Chen D, Lin X, Tang C
ACS biomaterials science & engineering 2024 Feb 12;10(2):1062-1076
ACS biomaterials science & engineering 2024 Feb 12;10(2):1062-1076
NIR Laser Irradiation Promotes Osteogenic Differentiation of PDLSCs Through the Activation of TRPV1 Channels and Subsequent Calcium Signaling.
Zeng JH, Ma B, Shen XQ, Geng YM
Photobiomodulation, photomedicine, and laser surgery 2024 Dec;42(12):747-753
Photobiomodulation, photomedicine, and laser surgery 2024 Dec;42(12):747-753
Integrated-omics profiling unveils the disparities of host defense to ECM scaffolds during wound healing in aged individuals.
Chen SD, Chu CY, Wang CB, Yang Y, Xu ZY, Qu YL, Man Y
Biomaterials 2024 Dec;311:122685
Biomaterials 2024 Dec;311:122685
LPS‑mediated adaptation accelerates ecto‑MSCs differentiation into osteoblasts.
Lv D, Li B, Liu Z, Zhang Q, Cao S, Xu Y, Zhang Z
Molecular medicine reports 2024 Dec;30(6)
Molecular medicine reports 2024 Dec;30(6)
Osteoinductivity enhancement by tailoring the surface chemical bond status: A strategy to mobilize host bone growth factors for in situ bone regeneration.
Li R, Zhang K, Dong C, Wang K, Gu X, Qin Y
Materials today. Bio 2024 Dec;29:101256
Materials today. Bio 2024 Dec;29:101256
Injectable hyaluronate-based hydrogel with a dynamic/covalent dual-crosslinked architecture for bone tissue engineering: Enhancing osteogenesis and immune regulation.
Guo K, Li G, Yu Q, Yang Y, Liu H, Zhao Y, Huang Y, Zhang H, Li W
International journal of biological macromolecules 2024 Dec;282(Pt 5):137249
International journal of biological macromolecules 2024 Dec;282(Pt 5):137249
Modified Titanium Implants Satisfy the Demands of Diabetic Osseointegration via Sequential Regulation of Macrophages and Mesenchymal Stem Cells.
Ma B, Chen F, Liu X, Zhang Y, Gou S, Meng Q, Liu P, Cai K
Advanced healthcare materials 2024 Dec;13(30):e2401556
Advanced healthcare materials 2024 Dec;13(30):e2401556
Magnesium-Based Composite Calcium Phosphate Cement Promotes Osteogenesis and Angiogenesis for Minipig Vertebral Defect Regeneration.
Tian F, Zhao Y, Wang Y, Xu H, Liu Y, Liu R, Li H, Ning R, Wang C, Gao X, Luo R, Jia S, Zhu L, Hao D
ACS biomaterials science & engineering 2024 Dec 9;10(12):7577-7593
ACS biomaterials science & engineering 2024 Dec 9;10(12):7577-7593
A 0.2 T-0.4 T Static Magnetic Field Improves the Bone Quality of Mice Subjected to Hindlimb Unloading and Reloading Through the Dual Regulation of BMSCs via Iron Metabolism.
Wang J, Zhen C, Zhang G, Yang Z, Shang P
International journal of molecular sciences 2024 Dec 6;25(23)
International journal of molecular sciences 2024 Dec 6;25(23)
Single-cell RNA sequencing identifies the expression of hemoglobin in chondrocyte cell subpopulations in osteoarthritis.
Zhang Z, He T, Gu H, Zhao Y, Tang S, Han K, Hu Y, Wang H, Yu H
BMC molecular and cell biology 2024 Dec 30;25(1):28
BMC molecular and cell biology 2024 Dec 30;25(1):28
Single-cell view and a novel protective macrophage subset in perivascular adipose tissue in T2DM.
Li J, Tian Z, Zhang T, Jin J, Zhang X, Xie P, Lin H, Gu J, Wu Y, Wang X, Zhang S, Yan X, Guo D, Wang Z, Zhang Q
Cellular & molecular biology letters 2024 Dec 3;29(1):148
Cellular & molecular biology letters 2024 Dec 3;29(1):148
Expression of Lumican and Osteopontin in Perivascular Areas of the Glioblastoma Peritumoral Niche and Its Value for Prognosis.
Salinas MD, Rodriguez P, Rubio G, Valdor R
International journal of molecular sciences 2024 Dec 29;26(1)
International journal of molecular sciences 2024 Dec 29;26(1)
Icariin suppresses osteogenic differentiation and promotes bone regeneration in Porphyromonas gingivalis-infected conditions through EphA2-RhoA signaling pathway.
Wang W, Sun DF, Dong Z, Zhang WL
International immunopharmacology 2024 Dec 25;143(Pt 1):113302
International immunopharmacology 2024 Dec 25;143(Pt 1):113302
Single-cell dissection of multifocal bladder cancer reveals malignant and immune cells variation between primary and recurrent tumor lesions.
Liu S, Feng C, Tan L, Zhang D, Li YX, Han Y, Wang C
Communications biology 2024 Dec 19;7(1):1659
Communications biology 2024 Dec 19;7(1):1659
Dihydromyricetin-loaded oxidized polysaccharide/L-arginine chitosan adhesive hydrogel promotes bone regeneration by regulating PI3K/AKT signaling pathway and MAPK signaling pathway.
Yang J, Zhang L, Wang Y, Wang N, Wei H, Zhang S, Ding Q, Sun S, Ding C, Liu W
Carbohydrate polymers 2024 Dec 15;346:122614
Carbohydrate polymers 2024 Dec 15;346:122614
Magnetically Induced Anisotropic Microstructures on Polyethylene Glycol Hydrogel Facilitate BMSC Alignment and Osteogenic Differentiation.
Zhang H, Luo Y, Xu R, Cao X, Li G, Chen S
Gels (Basel, Switzerland) 2024 Dec 11;10(12)
Gels (Basel, Switzerland) 2024 Dec 11;10(12)
Vaspin facilitates the proliferation and osteogenic differentiation of periodontal ligament stem cells.
Jing Z, Feng X, Li X, Zhang X, Pan C
Journal of periodontal research 2024 Aug;59(4):812-820
Journal of periodontal research 2024 Aug;59(4):812-820
Tracing Immunological Interaction in Trimethylamine N-Oxide Hydrogel-Derived Zwitterionic Microenvironment During Promoted Diabetic Wound Regeneration.
Li Z, Li L, Yue M, Peng Q, Pu X, Zhou Y
Advanced materials (Deerfield Beach, Fla.) 2024 Aug;36(33):e2402738
Advanced materials (Deerfield Beach, Fla.) 2024 Aug;36(33):e2402738
Fluoride-induced hypertension by regulating RhoA/ROCK pathway and phenotypic transformation of vascular smooth muscle cells: In vitro and in vivo evidence.
Yang W, Lu C, Chu F, Bu K, Ma H, Wang Q, Jiao Z, Wang S, Yang X, Gao Y, Sun D, Sun H
Ecotoxicology and environmental safety 2024 Aug;281:116681
Ecotoxicology and environmental safety 2024 Aug;281:116681
Crebanine mitigates glucocorticoid-induced osteonecrosis of the femoral head by restoring bone remodelling homeostasis via attenuating oxidative stress.
Dong S, Ge J, Meng Q, Yuan T, Wang Y, Li Y, Lu Q, Song W, Li Z, Sun S
Journal of cellular and molecular medicine 2024 Aug;28(16):e70044
Journal of cellular and molecular medicine 2024 Aug;28(16):e70044
miR-200a-3p-enriched MSC-derived extracellular vesicles reverse erectile function in diabetic rats by targeting Keap1.
Zhang J, Zhao D, Zang Z, Ruan Z, Fu Q, Zhang K
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:116964
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:116964
Titanium nanoparticles released from orthopedic implants induce muscle fibrosis via activation of SNAI2.
Zhang G, Deng L, Jiang Z, Xiang G, Zeng Z, Zhang H, Wang Y
Journal of nanobiotechnology 2024 Aug 30;22(1):522
Journal of nanobiotechnology 2024 Aug 30;22(1):522
BRF1 promotes the odontogenic differentiation of dental pulp stem cells in pulpitis by inducing autophagy.
Zhou C, Wu Y, Teng Y, Zhang J, Liu J
Heliyon 2024 Aug 30;10(16):e35442
Heliyon 2024 Aug 30;10(16):e35442
PTPN14 aggravates neointimal hyperplasia via boosting PDGFRβ signaling in smooth muscle cells.
Ma Q, He X, Wang X, Zhao G, Zhang Y, Su C, Wei M, Zhang K, Liu M, Zhu Y, He J
Nature communications 2024 Aug 27;15(1):7398
Nature communications 2024 Aug 27;15(1):7398
Identification of diagnostic biomarkers and immune cell infiltration in tongue squamous cell carcinoma using bioinformatic approaches.
Shi M, Dou H, Lou X, Jiang W, Wang H, Su Y
European journal of medical research 2024 Aug 21;29(1):428
European journal of medical research 2024 Aug 21;29(1):428
Toll-like receptor 4 deficiency affects the balance of osteoclastogenesis and osteoblastogenesis in periodontitis.
Pan L, She H, Hu Y, Liu L, Wang H, Zhu L
International immunopharmacology 2024 Aug 20;137:112500
International immunopharmacology 2024 Aug 20;137:112500
M2 Macrophage-Derived Exosomes Inhibit Atherosclerosis Progression by Regulating the Proliferation, Migration, and Phenotypic Transformation of Smooth Muscle Cells.
Wang S, Wang X, Lv Y, Zhang Z, He T, Hao X, Wang S, Wang C, Meng J, Zhong K, Ye Z, Chen T, Cui Y
Frontiers in bioscience (Landmark edition) 2024 Aug 19;29(8):288
Frontiers in bioscience (Landmark edition) 2024 Aug 19;29(8):288
Integrative analysis unveils ECM signatures and pathways driving hepatocellular carcinoma progression: A multi-omics approach and prognostic model development.
Liu Z, Zhao P
Journal of cellular and molecular medicine 2024 Apr;28(8):e18230
Journal of cellular and molecular medicine 2024 Apr;28(8):e18230
Phytic acid promotes high glucose-mediated bone marrow mesenchymal stem cells osteogenesis via modulating circEIF4B that sponges miR-186-5p and complexes with IGF2BP3.
Wu J, Li X, Nie H, Shen Y, Guo Z, Huihan Chu C, Cai K, Tang C
Biochemical pharmacology 2024 Apr;222:116118
Biochemical pharmacology 2024 Apr;222:116118
CGRP attenuates pulmonary vascular remodeling by inhibiting the cGAS-STING-NFκB pathway in pulmonary arterial hypertension.
Yan X, Huang J, Zeng Y, Zhong X, Fu Y, Xiao H, Wang X, Lian H, Luo H, Li D, Guo R
Biochemical pharmacology 2024 Apr;222:116093
Biochemical pharmacology 2024 Apr;222:116093
Complex intrinsic abnormalities in osteoblast lineage cells of X-linked hypophosphatemia: Analysis of human iPS cell models generated by CRISPR/Cas9-mediated gene ablation.
Nakanishi T, Yamazaki M, Tachikawa K, Ueta A, Kawai M, Ozono K, Michigami T
Bone 2024 Apr;181:117044
Bone 2024 Apr;181:117044
Improving osseointegration and antimicrobial properties of titanium implants with black phosphorus nanosheets-hydroxyapatite composite coatings for vascularized bone regeneration.
Ma S, Sun R, Wang Y, Wei Y, Xu H, Liu X, Liang Z, Zhao L, Hu Y, Lian X, Guo M, Huang D
Journal of biomedical materials research. Part B, Applied biomaterials 2024 Apr;112(4):e35403
Journal of biomedical materials research. Part B, Applied biomaterials 2024 Apr;112(4):e35403
Suramin inhibits phenotypic transformation of vascular smooth muscle cells and neointima hyperplasia by suppressing transforming growth factor beta receptor 1 /Smad2/3 pathway activation.
Xu Y, Ge L, Rui Y, Wang Y, Wang Z, Yang J, Shi Y, Dong Z, Zhang Y, Zhang R, Yang T, Lv L, Xiang F, Chen S, Song A, Li T, Liu M, Guo Y
European journal of pharmacology 2024 Apr 5;968:176422
European journal of pharmacology 2024 Apr 5;968:176422
Single-Cell Transcriptional Profile Construction of Rat Pituitary Glands before and after Sexual Maturation and Identification of Novel Marker Spp1 in Gonadotropes.
Huang QH, Zhao GK, Wang HQ, Wei FH, Zhang JY, Zhang JB, Gao F, Yuan B
International journal of molecular sciences 2024 Apr 25;25(9)
International journal of molecular sciences 2024 Apr 25;25(9)
Chromosomal 3q amplicon encodes essential regulators of secretory vesicles that drive secretory addiction in cancer.
Tan X, Wang S, Xiao GY, Wu C, Liu X, Zhou B, Jiang Y, Duose DY, Xi Y, Wang J, Gupta K, Pataer A, Roth JA, Kim MP, Chen F, Creighton CJ, Russell WK, Kurie JM
The Journal of clinical investigation 2024 Apr 25;134(12)
The Journal of clinical investigation 2024 Apr 25;134(12)
Trimethylamine N-oxide Promotes Atherosclerosis by Regulating Low-Density Lipoprotein-Induced Autophagy in Vascular Smooth Muscle Cells Through PI3K/AKT/mTOR Pathway.
Shi G, Zeng L, Shi J, Chen Y
International heart journal 2023;64(3):462-469
International heart journal 2023;64(3):462-469
miR-145 Alleviates Smooth Muscle Cell Phenotype Transition via ADAM17-Mediated ACE2 Shedding.
Wen J, Tang B, Guo L, Chen W, Tang X
International journal of hypertension 2023;2023:9497716
International journal of hypertension 2023;2023:9497716
Protective Effect of Alkaline Mineral Water on Calcium Oxalate-Induced Kidney Injury in Mice.
Liu L, Lin C, Li X, Cheng Y, Wang R, Luo C, Zhao X, Jiang Z
Evidence-based complementary and alternative medicine : eCAM 2023;2023:4559802
Evidence-based complementary and alternative medicine : eCAM 2023;2023:4559802
Therapeutic Effects of Mechanical Stress-Induced C2C12-Derived Exosomes on Glucocorticoid-Induced Osteoporosis Through miR-92a-3p/PTEN/AKT Signaling Pathway.
Xu N, Cui G, Zhao S, Li Y, Liu Q, Liu X, Zhao C, Feng R, Kuang M, Han S
International journal of nanomedicine 2023;18:7583-7603
International journal of nanomedicine 2023;18:7583-7603
High-fat diet causes undesirable bone regeneration by altering the bone marrow environment in rats.
Cai F, Yusufu A, Liu K, Chen W, Zhao R, Liu Y, Liu Y
Frontiers in endocrinology 2023;14:1088508
Frontiers in endocrinology 2023;14:1088508
Ectomesenchymal Six1 controls mandibular skeleton formation.
Luo S, Liu Z, Bian Q, Wang X
Frontiers in genetics 2023;14:1082911
Frontiers in genetics 2023;14:1082911
S-propargyl-cysteine promotes the stability of atherosclerotic plaque via maintaining vascular muscle contractile phenotype.
Ping L, Zhi-Ming L, Bi-Shan Z, Lei Z, Bo Y, Yi-Chun Z, Ming-Jie W
Frontiers in cell and developmental biology 2023;11:1291170
Frontiers in cell and developmental biology 2023;11:1291170
Sustained delivery of osteogenic growth peptide through injectable photoinitiated composite hydrogel for osteogenesis.
Liu B, Wu J, Sun X, Meng Q, Zhang J
Frontiers in bioengineering and biotechnology 2023;11:1228250
Frontiers in bioengineering and biotechnology 2023;11:1228250
Mir-142-5p inhibits the osteogenic differentiation of bone marrow mesenchymal stem cells by targeting Lhx8.
Du Y, Zhong H, Yu C, Lv Y, Yao Y, Peng Z, Lu S
Heliyon 2023 Sep;9(9):e19878
Heliyon 2023 Sep;9(9):e19878
The response and resistance to drugs in ovarian cancer cell lines in 2D monolayers and 3D spheroids.
Świerczewska M, Sterzyńska K, Ruciński M, Andrzejewska M, Nowicki M, Januchowski R
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115152
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115152
Effect of sulfonation time on physicochemical, osteogenic, antibacterial properties and biocompatibility of carbon fiber reinforced polyether ether ketone.
Su J, Wu Q, Xing X, Li D, Ou Y, He K, Lin H, Qiu Y, Rausch-Fan X, Chen J
Journal of the mechanical behavior of biomedical materials 2023 Sep;145:105979
Journal of the mechanical behavior of biomedical materials 2023 Sep;145:105979
Milk-Derived Small Extracellular Vesicles Promote Osteogenic Differentiation and Inhibit Inflammation via microRNA-21.
Liu R, Liu S, Wu S, Xia M, Liu W, Wang L, Dong M, Niu W
International journal of molecular sciences 2023 Sep 8;24(18)
International journal of molecular sciences 2023 Sep 8;24(18)
Single-cell epigenome analysis identifies molecular events controlling direct conversion of human fibroblasts to pancreatic ductal-like cells.
Fei L, Zhang K, Poddar N, Hautaniemi S, Sahu B
Developmental cell 2023 Sep 25;58(18):1701-1715.e8
Developmental cell 2023 Sep 25;58(18):1701-1715.e8
A composite membrane with microtopographical morphology to regulate cellular behavior for improved tissue regeneration.
Zhang R, Gong Y, Cai Z, Deng Y, Shi X, Pan H, Xu L, Zhang H
Acta biomaterialia 2023 Sep 15;168:125-143
Acta biomaterialia 2023 Sep 15;168:125-143
Inhibition of AT1R/IP3/IP3R-mediated Ca(2+) release protects against calcium oxalate crystals-induced renal oxidative stress.
Hong SY, Yang YY, Wang SG, Qin BL
Chemico-biological interactions 2023 Sep 1;382:110636
Chemico-biological interactions 2023 Sep 1;382:110636
A nano-conductive osteogenic hydrogel to locally promote calcium influx for electro-inspired bone defect regeneration.
Yu C, Ying X, Shahbazi MA, Yang L, Ma Z, Ye L, Yang W, Sun R, Gu T, Tang R, Fan S, Yao S
Biomaterials 2023 Oct;301:122266
Biomaterials 2023 Oct;301:122266
lncRNA MEG3 Promotes Osteogenic Differentiation of Tendon Stem Cells Via the miR-129-5p/TCF4/β-Catenin Axis and thus Contributes to Trauma-Induced Heterotopic Ossification.
Liu H, Sun Z, Luo G, Hu Y, Ruan H, Tu B, Li J, Fan C
Stem cell reviews and reports 2023 Oct;19(7):2311-2328
Stem cell reviews and reports 2023 Oct;19(7):2311-2328
Ganoderma lucidum polysaccharide peptide (GLPP) attenuates rheumatic arthritis in rats through inactivating NF-κB and MAPK signaling pathways.
Meng M, Wang L, Yao Y, Lin D, Wang C, Yao J, Sun H, Liu M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155010
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155010
Sodium-glucose cotransporter 2 inhibitor canagliflozin alleviates vascular calcification through suppression of nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing-3 inflammasome.
Chen A, Lan Z, Li L, Xie L, Liu X, Yang X, Wang S, Liang Q, Dong Q, Feng L, Li Y, Ye Y, Fu M, Lu L, Yan J
Cardiovascular research 2023 Oct 24;119(13):2368-2381
Cardiovascular research 2023 Oct 24;119(13):2368-2381
The Wnt/β-catenin signaling pathway inhibits osteoporosis by regulating the expression of TERT: an in vivo and in vitro study.
Cai Y, Sun H, Song X, Zhao J, Xu D, Liu M
Aging 2023 Oct 19;15(20):11471-11488
Aging 2023 Oct 19;15(20):11471-11488
Knockdown of Bach1 protects periodontal bone regeneration from inflammatory damage.
Yuan Z, Li J, Zou X, Liu C, Lu J, Ni C, Tang L, Wu X, Yan F
Journal of cellular and molecular medicine 2023 Nov;27(22):3465-3477
Journal of cellular and molecular medicine 2023 Nov;27(22):3465-3477
Impaired Growth Plate Maturation in XLH Is due to Both Excess FGF23 and Decreased 1,25-Dihydroxyvitamin D Signaling.
Yadav PS, Kobelski MM, Martins JS, Tao T, Liu ES, Demay MB
Endocrinology 2023 Nov 20;165(1)
Endocrinology 2023 Nov 20;165(1)
Melatonin-Primed Mesenchymal Stem Cells-Derived Small Extracellular Vesicles Alleviated Neurogenic Erectile Dysfunction by Reversing Phenotypic Modulation.
Chen Z, Zhai J, Ma J, Chen P, Lin W, Zhang W, Xiong J, Zhang C, Wei H
Advanced healthcare materials 2023 May;12(12):e2203087
Advanced healthcare materials 2023 May;12(12):e2203087
Apatinib remodels the immunosuppressive tumor ecosystem of gastric cancer enhancing anti-PD-1 immunotherapy.
Luo Q, Dong Z, Xie W, Fu X, Lin L, Zeng Q, Chen Y, Ye G, Chen M, Hu H, Wang L, Xie Y, Cai W
Cell reports 2023 May 30;42(5):112437
Cell reports 2023 May 30;42(5):112437
Apolipoprotein E facilitates titanium implant osseointegration by regulating osteogenesis-lipogenesis balance.
Wang YN, Yu L, Wang T, Liu S
International journal of biological macromolecules 2023 May 1;236:123998
International journal of biological macromolecules 2023 May 1;236:123998
Realizing Highly Efficient Sonodynamic Bactericidal Capability through the Phonon-Electron Coupling Effect Using Two-Dimensional Catalytic Planar Defects.
Mao C, Jin W, Xiang Y, Zhu Y, Wu J, Liu X, Wu S, Zheng Y, Cheung KMC, Yeung KWK
Advanced materials (Deerfield Beach, Fla.) 2023 Mar;35(9):e2208681
Advanced materials (Deerfield Beach, Fla.) 2023 Mar;35(9):e2208681
Mechanistic Insights into the Role of OPN in Mediating Brain Damage via Triggering Lysosomal Damage in Microglia/Macrophage.
Gai C, Zhao Y, Xin D, Li T, Cheng Y, Jiang Z, Song Y, Liu D, Wang Z
Cells 2023 Mar 9;12(6)
Cells 2023 Mar 9;12(6)
Bioinspired Piezoelectric Periosteum to Augment Bone Regeneration via Synergistic Immunomodulation and Osteogenesis.
Liu H, Shi Y, Zhu Y, Wu P, Deng Z, Dong Q, Wu M, Cai L
ACS applied materials & interfaces 2023 Mar 8;15(9):12273-12293
ACS applied materials & interfaces 2023 Mar 8;15(9):12273-12293
IL-1β contributes to the secretion of sclerostin by osteocytes and targeting sclerostin promotes spinal fusion at early stages.
Jiang Z, Jin L, Jiang C, Yan Z, Cao Y
Journal of orthopaedic surgery and research 2023 Mar 3;18(1):162
Journal of orthopaedic surgery and research 2023 Mar 3;18(1):162
FAM3A mediates the phenotypic switch of human aortic smooth muscle cells stimulated with oxidised low-density lipoprotein by influencing the PI3K-AKT pathway.
Yang L, Du B, Zhang S, Wang M
In vitro cellular & developmental biology. Animal 2023 Jun;59(6):431-442
In vitro cellular & developmental biology. Animal 2023 Jun;59(6):431-442
Bone microenvironment regulative hydrogels with ROS scavenging and prolonged oxygen-generating for enhancing bone repair.
Sun H, Xu J, Wang Y, Shen S, Xu X, Zhang L, Jiang Q
Bioactive materials 2023 Jun;24:477-496
Bioactive materials 2023 Jun;24:477-496
Continuously released Zn(2+) in 3D-printed PLGA/β-TCP/Zn scaffolds for bone defect repair by improving osteoinductive and anti-inflammatory properties.
Li C, Sun F, Tian J, Li J, Sun H, Zhang Y, Guo S, Lin Y, Sun X, Zhao Y
Bioactive materials 2023 Jun;24:361-375
Bioactive materials 2023 Jun;24:361-375
The marriage of immunomodulatory, angiogenic, and osteogenic capabilities in a piezoelectric hydrogel tissue engineering scaffold for military medicine.
Wu P, Shen L, Liu HF, Zou XH, Zhao J, Huang Y, Zhu YF, Li ZY, Xu C, Luo LH, Luo ZQ, Wu MH, Cai L, Li XK, Wang ZG
Military Medical Research 2023 Jul 31;10(1):35
Military Medical Research 2023 Jul 31;10(1):35
Clock genes are expressed in cementum and regulate the proliferation and mineralization of cementoblasts.
Liu G, Sun Q, Wu X, Liu Y, Chen Y, Cao Z, Hu Y, Xia H
In vitro cellular & developmental biology. Animal 2023 Jan;59(1):76-84
In vitro cellular & developmental biology. Animal 2023 Jan;59(1):76-84
Circular RNA CircSLC8A1 contributes to osteogenic differentiation in hBMSCs via CircSLC8A1/miR-144-3p/RUNX1 in periprosthetic osteolysis.
Yang B, Qin Y, Zhang A, Wang P, Jiang H, Shi Y, You G, Shen D, Ni S, Guo L, Liu Y
Journal of cellular and molecular medicine 2023 Jan;27(2):189-203
Journal of cellular and molecular medicine 2023 Jan;27(2):189-203
Single-cell RNA sequencing analysis revealed cellular and molecular immune profiles in lung squamous cell carcinoma.
Hao B, Zhang Z, Lu Z, Xiong J, Fan T, Song C, He R, Zhang L, Pan S, Li D, Meng H, Lin W, Luo B, Yang J, Li N, Geng Q
Translational oncology 2023 Jan;27:101568
Translational oncology 2023 Jan;27:101568
A TEMPOL and rapamycin loaded nanofiber-covered stent favors endothelialization and mitigates neointimal hyperplasia and local inflammation.
Wang R, Lu J, Yin J, Chen H, Liu H, Xu F, Zang T, Xu R, Li C, Wu Y, Wu Q, Fei X, Zhu M, Shen L, Ge J
Bioactive materials 2023 Jan;19:666-677
Bioactive materials 2023 Jan;19:666-677
Reversing the imbalance in bone homeostasis via sustained release of SIRT-1 agonist to promote bone healing under osteoporotic condition.
Zhang W, Zhou X, Hou W, Chen E, Ye C, Chen M, Lu Q, Yu X, Li W
Bioactive materials 2023 Jan;19:429-443
Bioactive materials 2023 Jan;19:429-443
Calcium Phosphate Bone Cements Incorporated with Black Phosphorus Nanosheets Enhanced Osteogenesis.
Ma S, Wei Y, Sun R, Xu H, Liu X, Wang Y, Liang Z, Hu Y, Lian X, Ma X, Huang D
ACS biomaterials science & engineering 2023 Jan 9;9(1):292-302
ACS biomaterials science & engineering 2023 Jan 9;9(1):292-302
Cannabidiol Rescues TNF-α-Inhibited Proliferation, Migration, and Osteogenic/Odontogenic Differentiation of Dental Pulp Stem Cells.
Yu L, Zeng L, Zhang Z, Zhu G, Xu Z, Xia J, Weng J, Li J, Pathak JL
Biomolecules 2023 Jan 6;13(1)
Biomolecules 2023 Jan 6;13(1)
PKR deficiency delays vascular aging via inhibiting GSDMD-mediated endothelial cell hyperactivation.
Peng Z, Tan X, Xie L, Li Z, Zhou S, Li Y
iScience 2023 Jan 20;26(1):105909
iScience 2023 Jan 20;26(1):105909
Bta-miR-200b promotes endometrial epithelial cell apoptosis by targeting MYB in cattle.
Lyu S, Zhai Y, Zhu X, Shi Q, Chen F, Zhang G, Zhang Z, Wang E
Theriogenology 2023 Jan 1;195:77-84
Theriogenology 2023 Jan 1;195:77-84
Type 1 diabetes mellitus leads to gingivitis and an early compensatory increase in bone remodeling.
Yuan X, Amin V, Zhu T, Kittaka M, Ueki Y, Bellido TM, Turkkahraman H
Journal of periodontology 2023 Feb;94(2):277-289
Journal of periodontology 2023 Feb;94(2):277-289
Metformin enhances the osteogenic activity of rat bone marrow mesenchymal stem cells by inhibiting oxidative stress induced by diabetes mellitus: an in vitro and in vivo study.
Dong K, Zhou WJ, Liu ZH
Journal of periodontal & implant science 2023 Feb;53(1):54-68
Journal of periodontal & implant science 2023 Feb;53(1):54-68
Ferroptotic stress facilitates smooth muscle cell dedifferentiation in arterial remodelling by disrupting mitochondrial homeostasis.
Ji QX, Zeng FY, Zhou J, Wu WB, Wang XJ, Zhang Z, Zhang GY, Tong J, Sun DY, Zhang JB, Cao WX, Shen FM, Lu JJ, Li DJ, Wang P
Cell death and differentiation 2023 Feb;30(2):457-474
Cell death and differentiation 2023 Feb;30(2):457-474
Macrophage migration inhibitory factor (MIF) inhibitor iSO-1 promotes staphylococcal protein A-induced osteogenic differentiation by inhibiting NF-κB signaling pathway.
Shi X, Wu Y, Ni H, Li M, Qi B, Xu Y
International immunopharmacology 2023 Feb;115:109600
International immunopharmacology 2023 Feb;115:109600
Stimulus-Responsive Zwitterionic Prodrug Delivery System with Sustained Release of Hydrogen Sulfide for Protective Aortic Dissection.
Ren B, Liu R, He Q, Wu T, Song L, Wang H, Gu J
ACS applied materials & interfaces 2023 Feb 22;15(7):9099-9109
ACS applied materials & interfaces 2023 Feb 22;15(7):9099-9109
Influence of FOSL1 Inhibition on Vascular Calcification and ROS Generation through Ferroptosis via P53-SLC7A11 Axis.
Shao S, Liu Y, Hong W, Mo Y, Shu F, Jiang L, Tan N
Biomedicines 2023 Feb 20;11(2)
Biomedicines 2023 Feb 20;11(2)
Retrospective identification of intrinsic factors that mark pluripotency potential in rare somatic cells.
Jain N, Goyal Y, Dunagin MC, Cote CJ, Mellis IA, Emert B, Jiang CL, Dardani IP, Reffsin S, Raj A
bioRxiv : the preprint server for biology 2023 Feb 10;
bioRxiv : the preprint server for biology 2023 Feb 10;
Hypoxia Inhibits Cell Cycle Progression and Cell Proliferation in Brain Microvascular Endothelial Cells via the miR-212-3p/MCM2 Axis.
Shi Q, Li S, Lyu Q, Zhang S, Bai Y, Ma J
International journal of molecular sciences 2023 Feb 1;24(3)
International journal of molecular sciences 2023 Feb 1;24(3)
Co-overexpression of OPN, IGF-1 and CNTF augment the therapeutic effect of DPSC on spinal cord injury.
Tao N, Dong X, Liu C, Lv L, Hu F, Zhang H, Li X, Geng P, Duan H, Wu CT, Wang H
Regenerative therapy 2023 Dec;24:651-661
Regenerative therapy 2023 Dec;24:651-661
Engineered muscle from micro-channeled PEG scaffold with magnetic Fe(3)O(4) fixation towards accelerating esophageal muscle repair.
Luo Y, Chen Y, Gu Z, Ni R, Feng P, Hu Z, Song L, Shen X, Gu C, Li J, Du T, Yang L, Zhang H, Zhu Y
Materials today. Bio 2023 Dec;23:100853
Materials today. Bio 2023 Dec;23:100853
Overexpression of LOX-1 in hepatocytes protects vascular smooth muscle cells from phenotype transformation and wire injury induced carotid neoatherosclerosis through ALOX15.
Zhang Q, Du G, Tong L, Guo X, Wei Y
Biochimica et biophysica acta. Molecular basis of disease 2023 Dec;1869(8):166805
Biochimica et biophysica acta. Molecular basis of disease 2023 Dec;1869(8):166805
CDN1163 alleviates SERCA2 dysfunction-induced pulmonary vascular remodeling by inhibiting the phenotypic transition of pulmonary artery smooth muscle cells.
Yu W, Zhang Q, Qiu Y, Chen H, Huang X, Xiao L, Xu G, Li S, Hu P, Tong X
Clinical and experimental hypertension (New York, N.Y. : 1993) 2023 Dec 31;45(1):2272062
Clinical and experimental hypertension (New York, N.Y. : 1993) 2023 Dec 31;45(1):2272062
Non-canonical function of histone methyltransferase G9a in the translational regulation of chronic inflammation.
Muneer A, Wang L, Xie L, Zhang F, Wu B, Mei L, Lenarcic EM, Feng EH, Song J, Xiong Y, Yu X, Wang C, Jain K, Strahl BD, Cook JG, Wan YY, Moorman NJ, Song H, Jin J, Chen X
Cell chemical biology 2023 Dec 21;30(12):1525-1541.e7
Cell chemical biology 2023 Dec 21;30(12):1525-1541.e7
The LRP5 high-bone-mass mutation causes alveolar bone accrual with minor craniofacial alteration.
Turkkahraman H, Flanagan S, Zhu T, Bellido TM, Yuan X
Journal of periodontal research 2023 Aug;58(4):723-732
Journal of periodontal research 2023 Aug;58(4):723-732
Transcription factor 21 accelerates vascular calcification in mice by activating the IL-6/STAT3 signaling pathway and the interplay between VSMCs and ECs.
Zhao XK, Zhu MM, Wang SN, Zhang TT, Wei XN, Wang CY, Zheng J, Zhu WY, Jiang MX, Xu SW, Yang XX, Duan YJ, Zhang BC, Han JH, Miao QR, Hu H, Chen YL
Acta pharmacologica Sinica 2023 Aug;44(8):1625-1636
Acta pharmacologica Sinica 2023 Aug;44(8):1625-1636
A Recombinant Parathyroid Hormone-Related Peptide Locally Applied in Osteoporotic Bone Defect.
Wang Y, Hu Y, Lan S, Chen Z, Zhang Y, Guo X, Cai L, Li J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Aug;10(22):e2300516
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Aug;10(22):e2300516
miR-342-5p promotes vascular smooth muscle cell phenotypic transition through a negative-feedback regulation of Notch signaling via targeting FOXO3.
Wen T, Duan Y, Gao D, Zhang X, Zhang X, Liang L, Yang Z, Zhang P, Zhang J, Sun J, Feng Y, Zheng Q, Han H, Yan X
Life sciences 2023 Aug 1;326:121828
Life sciences 2023 Aug 1;326:121828
Changes in N6-methyladenosine RNA methylomes of human periodontal ligament cells in response to inflammatory conditions.
Zou X, Liu C, Wu X, Yuan Z, Yan F
Journal of periodontal research 2023 Apr;58(2):444-455
Journal of periodontal research 2023 Apr;58(2):444-455
Nitration of cAMP-Response Element Binding Protein Participates in Myocardial Infarction-Induced Myocardial Fibrosis via Accelerating Transcription of Col1a2 and Cxcl12.
Xue K, Chen S, Chai J, Yan W, Zhu X, Ji D, Wu Y, Liu H, Wang W
Antioxidants & redox signaling 2023 Apr;38(10-12):709-730
Antioxidants & redox signaling 2023 Apr;38(10-12):709-730
Identification of hub genes and pathways in lung metastatic colorectal cancer.
Dai W, Guo C, Wang Y, Li Y, Xie R, Wu J, Yao B, Xie D, He L, Li Y, Huang H, Wang Y, Liu S
BMC cancer 2023 Apr 6;23(1):323
BMC cancer 2023 Apr 6;23(1):323
EMT-activated secretory and endocytic vesicular trafficking programs underlie a vulnerability to PI4K2A antagonism in lung cancer.
Tan X, Xiao GY, Wang S, Shi L, Zhao Y, Liu X, Yu J, Russell WK, Creighton CJ, Kurie JM
The Journal of clinical investigation 2023 Apr 3;133(7)
The Journal of clinical investigation 2023 Apr 3;133(7)
Osteopontin Promotes Macrophage M1 Polarization by Activation of the JAK1/STAT1/HMGB1 Signaling Pathway in Nonalcoholic Fatty Liver Disease.
Xu Z, Xi F, Deng X, Ni Y, Pu C, Wang D, Lou W, Zeng X, Su N, Chen C, Zeng Z, Deng L, Jiang M
Journal of clinical and translational hepatology 2023 Apr 28;11(2):273-283
Journal of clinical and translational hepatology 2023 Apr 28;11(2):273-283
Synergistic Effect of Magneto-Mechanical Bioengineered Stem Cells and Magnetic Field to Alleviate Osteoporosis.
Yu C, Yang W, Yang L, Ye L, Sun R, Gu T, Ying X, Wang M, Tang R, Fan S, Yao S
ACS applied materials & interfaces 2023 Apr 26;15(16):19976-19988
ACS applied materials & interfaces 2023 Apr 26;15(16):19976-19988
BRG1 is involved in vascular calcification in chronic renal disease via autophagy of vascular smooth muscle cells.
Feng Y, Yu M, Wang C, Xia J, Huang L, Tang Y, Xiao Q, Pu L, Wang L, Li G, Li Y
iScience 2023 Apr 21;26(4):106485
iScience 2023 Apr 21;26(4):106485
Potential of an Aligned Porous Hydrogel Scaffold Combined with Periodontal Ligament Stem Cells or Gingival Mesenchymal Stem Cells to Promote Tissue Regeneration in Rat Periodontal Defects.
Wang W, Wang A, Hu G, Bian M, Chen L, Zhao Q, Sun W, Wu Y
ACS biomaterials science & engineering 2023 Apr 10;9(4):1961-1975
ACS biomaterials science & engineering 2023 Apr 10;9(4):1961-1975
Biophysical Analysis and Preclinical Pharmacokinetics-Pharmacodynamics of Tangential Flow Filtration Fractionated Polymerized Human Hemoglobin as a Red Blood Cell Substitute.
Greenfield A, Lamb DR, Gu X, Thangaraju K, Setua S, Yahya A, Vahedi A, Khan MA, Wang Q, Buehler PW, Palmer AF
Biomacromolecules 2023 Apr 10;24(4):1855-1870
Biomacromolecules 2023 Apr 10;24(4):1855-1870
Shared gene characteristics and molecular mechanisms of macrophages M1 polarization in calcified aortic valve disease.
Qin M, Chen Q, Li N, Xu X, Wang C, Wang G, Xu Z
Frontiers in cardiovascular medicine 2022;9:1058274
Frontiers in cardiovascular medicine 2022;9:1058274
Hsa_circRNA_0008028 Deficiency Ameliorates High Glucose-Induced Proliferation, Calcification, and Autophagy of Vascular Smooth Muscle Cells via miR-182-5p/TRIB3 Axis.
Shi L, Li Y, Shi M, Li X, Li G, Cen J, Liu D, Wei C, Lin Y
Oxidative medicine and cellular longevity 2022;2022:5142381
Oxidative medicine and cellular longevity 2022;2022:5142381
Preparation and Biocompatibility of Core-Shell Microspheres for Sequential, Sustained Release of BMP-2 and VEGF.
Liu Z, Xu Z, Wang X, Zhang Y, Wu Y, Jiang D, Jia R
BioMed research international 2022;2022:4072975
BioMed research international 2022;2022:4072975
OPN Promotes Cell Proliferation and Invasion through NF-κB in Human Esophageal Squamous Cell Carcinoma.
Chen B, Liang S, Guo H, Xu L, Li J, Peng J
Genetics research 2022;2022:3154827
Genetics research 2022;2022:3154827
Assessing serum levels of SM22α as a new biomarker for patients with aortic aneurysm/dissection.
Zhang N, Wang YY, Hu HJ, Lu G, Xu X, Dou YQ, Cui W, Gao SJ, Han M
PloS one 2022;17(3):e0264942
PloS one 2022;17(3):e0264942
Akkermansia muciniphila Alters Gut Microbiota and Immune System to Improve Cardiovascular Diseases in Murine Model.
He X, Bai Y, Zhou H, Wu K
Frontiers in microbiology 2022;13:906920
Frontiers in microbiology 2022;13:906920
Pan-Cancer Analysis of the Immunological Role of PDIA5: A Potential Target for Immunotherapy.
Chen Y, He J, Chen R, Wang Z, Dai Z, Liang X, Wu W, Luo P, Zhang J, Peng Y, Zhang N, Liu Z, Zhang L, Zhang H, Cheng Q
Frontiers in immunology 2022;13:881722
Frontiers in immunology 2022;13:881722
Hypoxia During the Consolidation Phase of Distraction Osteogenesis Promotes Bone Regeneration.
Liu Y, Liu J, Cai F, Liu K, Zhang X, Yusufu A
Frontiers in physiology 2022;13:804469
Frontiers in physiology 2022;13:804469
Pan-Cancer Analysis Reveals a Distinct Neutrophil Extracellular Trap-Associated Regulatory Pattern.
Shen XT, Xie SZ, Xu J, Yang LY, Qin LX
Frontiers in immunology 2022;13:798022
Frontiers in immunology 2022;13:798022
CCAAT/Enhancer-Binding Protein Alpha Is a Novel Regulator of Vascular Smooth Muscle Cell Osteochondrogenic Transition and Vascular Calcification.
Chen P, Hong W, Chen Z, Gordillo-Martinez F, Wang S, Fan H, Liu Y, Dai Y, Wang B, Jiang L, Yu H, He P
Frontiers in physiology 2022;13:755371
Frontiers in physiology 2022;13:755371
TSH-SPP1/TRβ-TSH positive feedback loop mediates fat deposition of hepatocyte: Crosstalk between thyroid and liver.
Huang B, Wen W, Ye S
Frontiers in immunology 2022;13:1009912
Frontiers in immunology 2022;13:1009912
Dissecting a hypoxia-related angiogenic gene signature for predicting prognosis and immune status in hepatocellular carcinoma.
Zhang G, Xiao Y, Zhang X, Fan W, Zhao Y, Wu Y, Wang H, Li J
Frontiers in oncology 2022;12:978050
Frontiers in oncology 2022;12:978050
Potassium Titanate Assembled Titanium Dioxide Nanotube Arrays Endow Titanium Implants Excellent Osseointegration Performance and Nerve Formation Potential.
Zhao H, Liu F, Yin Y, Wang S
Frontiers in chemistry 2022;10:839093
Frontiers in chemistry 2022;10:839093
Construction and osteogenic effects of 3D-printed porous titanium alloy loaded with VEGF/BMP-2 shell-core microspheres in a sustained-release system.
Liu Z, Xu Z, Wang X, Zhang Y, Wu Y, Jiang D, Jia R
Frontiers in bioengineering and biotechnology 2022;10:1028278
Frontiers in bioengineering and biotechnology 2022;10:1028278
NRF2 is a critical regulator and therapeutic target of metal implant particle-incurred bone damage.
Dong J, Zhang L, Ruan B, Lv Z, Wang H, Wang Y, Jiang Q, Cao W
Biomaterials 2022 Sep;288:121742
Biomaterials 2022 Sep;288:121742
Negative pressure wound therapy improves bone regeneration by promoting osteogenic differentiation via the AMPK-ULK1-autophagy axis.
Zhang S, Xie Y, Yan F, Zhang Y, Yang Z, Chen Z, Zhao Y, Huang Z, Cai L, Deng Z
Autophagy 2022 Sep;18(9):2229-2245
Autophagy 2022 Sep;18(9):2229-2245
Dual Biosignal-Functional Injectable Microspheres for Remodeling Osteogenic Microenvironment.
Sun Y, Zhou Q, Du Y, Sun J, Bi W, Liu W, Li R, Wu X, Yang F, Song L, Li N, Cui W, Yu Y
Small (Weinheim an der Bergstrasse, Germany) 2022 Sep;18(36):e2201656
Small (Weinheim an der Bergstrasse, Germany) 2022 Sep;18(36):e2201656
Substitution of SERCA2 Cys(674) accelerates aortic aneurysm by inducing endoplasmic reticulum stress and promoting cell apoptosis.
Wang L, Yang Z, Wang S, Que Y, Shu X, Wu F, Liu G, Li S, Hu P, Chen H, Shi J, Tong X
British journal of pharmacology 2022 Sep;179(17):4423-4439
British journal of pharmacology 2022 Sep;179(17):4423-4439
The Protective Effects on Ischemia-Reperfusion Injury Mechanisms of the Thoracic Aorta in Daurian Ground Squirrels (Spermophilus dauricus) over the Torpor-Arousal Cycle of Hibernation.
Han Y, Miao W, Hao Z, An N, Yang Y, Zhang Z, Chen J, Storey KB, Lefai E, Chang H
International journal of molecular sciences 2022 Sep 6;23(18)
International journal of molecular sciences 2022 Sep 6;23(18)
Oxalate induces the ossification of RTECs by activating the JAK2/STAT3 signaling pathway and participates in the formation of kidney stones.
Song Q, Liao W, He Z, Li D, Dong C, Song C, Yang S
Archives of biochemistry and biophysics 2022 Sep 30;727:109325
Archives of biochemistry and biophysics 2022 Sep 30;727:109325
Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Enhance the Osteoblastic Differentiation of Periodontal Ligament Stem Cells Under High Glucose Conditions Through the PI3K/AKT Signaling Pathway.
Yang S, Zhu B, Tian XY, Yu HY, Qiao B, Zhao LS, Zhang B
Biomedical and environmental sciences : BES 2022 Sep 20;35(9):811-820
Biomedical and environmental sciences : BES 2022 Sep 20;35(9):811-820
Impact of Resolvin D1 on the inflammatory phenotype of periodontal ligament cell response to hypoxia.
Cai J, Liu J, Yan J, Lu X, Wang X, Li S, Mustafa K, Wang H, Xue Y, Mustafa M, Kantarci A, Xing Z
Journal of periodontal research 2022 Oct;57(5):1034-1042
Journal of periodontal research 2022 Oct;57(5):1034-1042
LncRNA LINC00281/Annexin A2 Regulates Vascular Smooth Muscle Cell Phenotype Switching via the Nuclear Factor-Kappa B Signaling Pathway.
Cheng L, Wang H, Maboh R, Mao G, Wu X, Chen H
Journal of cardiovascular translational research 2022 Oct;15(5):971-984
Journal of cardiovascular translational research 2022 Oct;15(5):971-984
Gut microbiome dysbiosis contributes to abdominal aortic aneurysm by promoting neutrophil extracellular trap formation.
Tian Z, Zhang Y, Zheng Z, Zhang M, Zhang T, Jin J, Zhang X, Yao G, Kong D, Zhang C, Wang Z, Zhang Q
Cell host & microbe 2022 Oct 12;30(10):1450-1463.e8
Cell host & microbe 2022 Oct 12;30(10):1450-1463.e8
Iron overload-induced ferroptosis of osteoblasts inhibits osteogenesis and promotes osteoporosis: An in vitro and in vivo study.
Jiang Z, Wang H, Qi G, Jiang C, Chen K, Yan Z
IUBMB life 2022 Nov;74(11):1052-1069
IUBMB life 2022 Nov;74(11):1052-1069
Identification of osteopontin as a urinary biomarker for autosomal dominant polycystic kidney disease progression.
Kim H, Sung J, Bae JY, Lee P, Oh YK, Kim H
Kidney research and clinical practice 2022 Nov;41(6):730-740
Kidney research and clinical practice 2022 Nov;41(6):730-740
Fecal microbiota transplantation ameliorates bone loss in mice with ovariectomy-induced osteoporosis via modulating gut microbiota and metabolic function.
Zhang YW, Cao MM, Li YJ, Lu PP, Dai GC, Zhang M, Wang H, Rui YF
Journal of orthopaedic translation 2022 Nov;37:46-60
Journal of orthopaedic translation 2022 Nov;37:46-60
Niobium promotes fracture healing in rats by regulating the PI3K-Akt signalling pathway: An in vivo and in vitro study.
Tan J, Li J, Cao B, Wu J, Luo D, Ran Z, Deng L, Li X, Jiang W, Xie K, Wang L, Hao Y
Journal of orthopaedic translation 2022 Nov;37:113-125
Journal of orthopaedic translation 2022 Nov;37:113-125
MiR-145 inhibits the differentiation and proliferation of bone marrow stromal mesenchymal stem cells by GABARAPL1 in steroid-induced femoral head necrosis.
Xu P, Chang J, Ma G, Liao F, Xu T, Wu Y, Yin Z
BMC musculoskeletal disorders 2022 Nov 26;23(1):1020
BMC musculoskeletal disorders 2022 Nov 26;23(1):1020
CircZXDC Promotes Vascular Smooth Muscle Cell Transdifferentiation via Regulating miRNA-125a-3p/ABCC6 in Moyamoya Disease.
Liu Y, Huang Y, Zhang X, Ma X, He X, Gan C, Zou X, Wang S, Shu K, Lei T, Zhang H
Cells 2022 Nov 26;11(23)
Cells 2022 Nov 26;11(23)
Decorin Promotes Osteoblastic Differentiation of Human Periodontal Ligament Stem Cells.
Adachi O, Sugii H, Itoyama T, Fujino S, Kaneko H, Tomokiyo A, Hamano S, Hasegawa D, Obata J, Yoshida S, Kadowaki M, Sugiura R, Albougha MS, Maeda H
Molecules (Basel, Switzerland) 2022 Nov 25;27(23)
Molecules (Basel, Switzerland) 2022 Nov 25;27(23)
Salidroside protects against osteoporosis in ovariectomized rats by inhibiting oxidative stress and promoting osteogenesis via Nrf2 activation.
Wang YF, Chang YY, Zhang XM, Gao MT, Zhang QL, Li X, Zhang L, Yao WF
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:154020
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:154020
Carboxymethyl chitin or chitosan for osteoinduction effect on the human periodontal ligament stem cells.
Fan C, Li Z, Ji Q, Sun H, Liang Y, Yang P
Dental materials journal 2022 May 31;41(3):392-401
Dental materials journal 2022 May 31;41(3):392-401
Intraoperative Hypothermia Induces Vascular Dysfunction in the CA1 Region of Rat Hippocampus.
Li T, Xu G, Yi J, Huang Y
Brain sciences 2022 May 27;12(6)
Brain sciences 2022 May 27;12(6)
Mussel-inspired multifunctional surface through promoting osteogenesis and inhibiting osteoclastogenesis to facilitate bone regeneration.
Wu M, Zhang Y, Wu P, Chen F, Yang Z, Zhang S, Xiao L, Cai L, Zhang C, Chen Y, Deng Z
NPJ Regenerative medicine 2022 May 13;7(1):29
NPJ Regenerative medicine 2022 May 13;7(1):29
STARD3NL inhibits the osteogenic differentiation by inactivating the Wnt/β-catenin pathway via binding to Annexin A2 in osteoporosis.
Xu Y, Bao X, Chen X, Wu P, Chen S, Zhang B, Ma J, Xu G, Ma D
Journal of cellular and molecular medicine 2022 Mar;26(5):1643-1655
Journal of cellular and molecular medicine 2022 Mar;26(5):1643-1655
Molecular feature of arterial remodeling in the brain arteriovenous malformation revealed by arteriovenous shunt rat model and RNA sequencing.
Chen B, Tao W, Yan L, Zeng M, Song L, Huang Z, Chen F
International immunopharmacology 2022 Jun;107:108653
International immunopharmacology 2022 Jun;107:108653
MicroRNA-27a-3p inhibits lung and skin fibrosis of systemic sclerosis by negatively regulating SPP1.
Cheng Q, Chen M, Wang H, Chen X, Wu H, Du Y, Xue J
Genomics 2022 Jul;114(4):110391
Genomics 2022 Jul;114(4):110391
Iron deficiency exacerbates aortic medial degeneration by inducing excessive mitochondrial fission.
Zhong X, Wu Q, Wang Z, Zhang M, Zheng S, Shi F, Chen Y, Che Y, Yuan S, Xing K
Food & function 2022 Jul 18;13(14):7666-7683
Food & function 2022 Jul 18;13(14):7666-7683
Semaphorin3A promotes osseointegration of titanium implants in osteoporotic rabbits.
Song A, Jiang F, Wang Y, Wang M, Wu Y, Zheng Y, Song X, Zhang W, Zhou J
Clinical oral investigations 2022 Jan;26(1):969-979
Clinical oral investigations 2022 Jan;26(1):969-979
Increased expression of osteopontin in subchondral bone promotes bone turnover and remodeling, and accelerates the progression of OA in a mouse model.
Lin C, Chen Z, Guo D, Zhou L, Lin S, Li C, Li S, Wang X, Lin B, Ding Y
Aging 2022 Jan 4;14(1):253-271
Aging 2022 Jan 4;14(1):253-271
SIRT6 protects vascular smooth muscle cells from osteogenic transdifferentiation via Runx2 in chronic kidney disease.
Li W, Feng W, Su X, Luo D, Li Z, Zhou Y, Zhu Y, Zhang M, Chen J, Liu B, Huang H
The Journal of clinical investigation 2022 Jan 4;132(1)
The Journal of clinical investigation 2022 Jan 4;132(1)
Development of Intracorporeal Differentiation of Stem Cells to Induce One-Step Mastoid Bone Reconstruction during Otitis Media Surgeries.
Park SH, Kim H, Lee YY, Kim YJ, Jang JH, Choo OS, Choung YH
Polymers 2022 Feb 23;14(5)
Polymers 2022 Feb 23;14(5)
Osteopontin expression in the invasive front stroma of colorectal adenocarcinoma is associated with tumor budding and prognosis.
Nakajima T, Uehara T, Iwaya M, Matsuda K, Wada M, Nagaya T, Ehara T, Ota H
Pathology, research and practice 2022 Dec;240:154190
Pathology, research and practice 2022 Dec;240:154190
Dickkopf1 (Dkk1) Alleviates Vascular Calcification by Regulating the Degradation of Phospholipase D1 (PLD1).
Li X, Liu XL, Li X, Zhao YC, Wang QQ, Zhong HY, Liu DD, Yuan C, Zheng TF, Zhang M
Journal of cardiovascular translational research 2022 Dec;15(6):1327-1339
Journal of cardiovascular translational research 2022 Dec;15(6):1327-1339
Halide-containing bioactive glasses enhance osteogenesis in vitro and in vivo.
Chen X, Liu Y, Zhao Y, Ouyang Z, Zhou H, Li L, Li L, Li F, Xie X, Hill RG, Wang S, Chen X
Biomaterials advances 2022 Dec;143:213173
Biomaterials advances 2022 Dec;143:213173
PVT1/miR-145-5p/HK2 modulates vascular smooth muscle cells phenotype switch via glycolysis: The new perspective on the spiral artery remodeling.
Wu M, Liu W, Huang H, Chen Z, Chen Y, Zhong Y, Jin Z, Liu X, Zou L
Placenta 2022 Dec;130:25-33
Placenta 2022 Dec;130:25-33
Mesoporous Silica Promotes Osteogenesis of Human Adipose-Derived Stem Cells Identified by a High-Throughput Microfluidic Chip Assay.
Chen X, Wang C, Hao M, Zhao H, Xia H, Yu L, Li D, Qiu J, Li H, Han L, Sang Y
Pharmaceutics 2022 Dec 6;14(12)
Pharmaceutics 2022 Dec 6;14(12)
Electroactive Hydroxyapatite/Carbon Nanofiber Scaffolds for Osteogenic Differentiation of Human Adipose-Derived Stem Cells.
Sun B, Sun Y, Han S, Zhang R, Wang X, Meng C, Ji T, Sun C, Ren N, Ge S, Liu H, Yu Y, Wang J
International journal of molecular sciences 2022 Dec 28;24(1)
International journal of molecular sciences 2022 Dec 28;24(1)
Multi-Transcriptomic Analysis Reveals the Heterogeneity and Tumor-Promoting Role of SPP1/CD44-Mediated Intratumoral Crosstalk in Gastric Cancer.
Xie W, Cheng J, Hong Z, Cai W, Zhuo H, Hou J, Lin L, Wei X, Wang K, Chen X, Song Y, Wang Z, Cai J
Cancers 2022 Dec 27;15(1)
Cancers 2022 Dec 27;15(1)
Icariin Treatment Rescues Diabetes Induced Bone Loss via Scavenging ROS and Activating Primary Cilia/Gli2/Osteocalcin Signaling Pathway.
Liu J, Cheng Q, Wu X, Zhu H, Deng X, Wang M, Yang S, Xu J, Chen Q, Li M, Liu X, Wang C
Cells 2022 Dec 16;11(24)
Cells 2022 Dec 16;11(24)
Circular RNA BIRC6 depletion promotes osteogenic differentiation of periodontal ligament stem cells via the miR-543/PTEN/PI3K/AKT/mTOR signaling pathway in the inflammatory microenvironment.
Zhao X, Sun W, Guo B, Cui L
Stem cell research & therapy 2022 Aug 13;13(1):417
Stem cell research & therapy 2022 Aug 13;13(1):417
The Annexin A2-Notch regulatory loop in hepatocytes promotes liver fibrosis in NAFLD by increasing osteopontin expression.
Wang G, Duan J, Pu G, Ye C, Li Y, Xiu W, Xu J, Liu B, Zhu Y, Wang C
Biochimica et biophysica acta. Molecular basis of disease 2022 Aug 1;1868(8):166413
Biochimica et biophysica acta. Molecular basis of disease 2022 Aug 1;1868(8):166413
Cinnamaldehyde protects against ligature-induced periodontitis through the inhibition of microbial accumulation and inflammatory responses of host immune cells.
Ou Y, Yan M, Gao G, Wang W, Lu Q, Chen J
Food & function 2022 Aug 1;13(15):8091-8106
Food & function 2022 Aug 1;13(15):8091-8106
Immunohistochemical expression of osteopontin and collagens in choroid plexus of human brains.
Wakamatsu K, Chiba Y, Murakami R, Matsumoto K, Miyai Y, Kawauchi M, Yanase K, Uemura N, Ueno M
Neuropathology : official journal of the Japanese Society of Neuropathology 2022 Apr;42(2):117-125
Neuropathology : official journal of the Japanese Society of Neuropathology 2022 Apr;42(2):117-125
N-acetylcysteine promotes cyclic mechanical stress-induced osteogenic differentiation of periodontal ligament stem cells by down-regulating Nrf2 expression.
Xi X, Li ZX, Zhao Y, Liu H, Chen S, Liu DX
Journal of dental sciences 2022 Apr;17(2):750-762
Journal of dental sciences 2022 Apr;17(2):750-762
Bmal1 promotes cementoblast differentiation and cementum mineralization via Wnt/β-catenin signaling.
Liu S, Zhou Y, Chen Y, Liu Y, Peng S, Cao Z, Xia H
Acta histochemica 2022 Apr;124(3):151868
Acta histochemica 2022 Apr;124(3):151868
Decoding the temporal and regional specification of microglia in the developing human brain.
Li Y, Li Z, Yang M, Wang F, Zhang Y, Li R, Li Q, Gong Y, Wang B, Fan B, Wang C, Chen L, Li H, Ong J, Teng Z, Jin L, Wang YL, Du P, Jiao J
Cell stem cell 2022 Apr 7;29(4):620-634.e6
Cell stem cell 2022 Apr 7;29(4):620-634.e6
ELAV-like RNA binding protein 1 regulates osteogenesis in diabetic osteoporosis: Involvement of divalent metal transporter 1.
Ren Y, Yang M, Wang X, Xu B, Xu Z, Su B
Molecular and cellular endocrinology 2022 Apr 15;546:111559
Molecular and cellular endocrinology 2022 Apr 15;546:111559
Role of (pro)renin receptor in cyclosporin A-induced nephropathy.
Hu J, Tan Y, Chen Y, Mo S, Hekking B, Su J, Pu M, Lu A, Du Y, Symons JD, Yang T
American journal of physiology. Renal physiology 2022 Apr 1;322(4):F437-F448
American journal of physiology. Renal physiology 2022 Apr 1;322(4):F437-F448
Bioinformatics analysis of laryngeal squamous cell carcinoma: seeking key candidate genes and pathways.
Ma J, Hu X, Dai B, Wang Q, Wang H
PeerJ 2021;9:e11259
PeerJ 2021;9:e11259
Nrf2 Activation Is Involved in Cyclic Mechanical Stress-Stimulated Osteogenic Differentiation in Periodontal Ligament Stem Cells via PI3K/Akt Signaling and HO1-SOD2 Interaction.
Xi X, Li Z, Liu H, Chen S, Liu D
Frontiers in cell and developmental biology 2021;9:816000
Frontiers in cell and developmental biology 2021;9:816000
Cyclic Distraction-Compression Dynamization Technique Enhances the Bone Formation During Distraction Osteogenesis.
Liu Y, Cai F, Liu K, Liu J, Zhang X, Yusufu A
Frontiers in bioengineering and biotechnology 2021;9:810723
Frontiers in bioengineering and biotechnology 2021;9:810723
Long Non-coding RNAs LOC100126784 and POM121L9P Derived From Bone Marrow Mesenchymal Stem Cells Enhance Osteogenic Differentiation via the miR-503-5p/SORBS1 Axis.
Xu Y, Xin R, Sun H, Long D, Li Z, Liao H, Xue T, Zhang Z, Kang Y, Mao G
Frontiers in cell and developmental biology 2021;9:723759
Frontiers in cell and developmental biology 2021;9:723759
FBS-Derived Exosomes as a Natural Nano-Scale Carrier for Icariin Promote Osteoblast Proliferation.
Dong M, Wu S, Xu H, Yu X, Wang L, Bai H, Niu W
Frontiers in bioengineering and biotechnology 2021;9:615920
Frontiers in bioengineering and biotechnology 2021;9:615920
PRDX2 Protects Against Atherosclerosis by Regulating the Phenotype and Function of the Vascular Smooth Muscle Cell.
Li J, Wang C, Wang W, Liu L, Zhang Q, Zhang J, Wang B, Wang S, Hou L, Gao C, Yu X, Sun L
Frontiers in cardiovascular medicine 2021;8:624796
Frontiers in cardiovascular medicine 2021;8:624796
Metformin Inhibits Abdominal Aortic Aneurysm Formation through the Activation of the AMPK/mTOR Signaling Pathway.
He J, Li N, Fan Y, Zhao X, Liu C, Hu X
Journal of vascular research 2021;58(3):148-158
Journal of vascular research 2021;58(3):148-158
The effects of PIKfyve inhibitor YM201636 on claudins and malignancy potential of nonsmall cell cancer cells.
DoĞan E, DÜzgÜn Z, Yildirim Z, Özdİl B, AktuĞ H, Bozok ÇetİntaŞ V
Turkish journal of biology = Turk biyoloji dergisi 2021;45(1):26-34
Turkish journal of biology = Turk biyoloji dergisi 2021;45(1):26-34
Quantitative Proteomics Reveals the Dynamic Pathophysiology Across Different Stages in a Rat Model of Severe Traumatic Brain Injury.
Luo W, Yang Z, Zhang W, Zhou D, Guo X, Wang S, He F, Wang Y
Frontiers in molecular neuroscience 2021;14:785938
Frontiers in molecular neuroscience 2021;14:785938
Dura cells in the etiopathogenesis of Crouzon syndrome: the effects of FGFR2 mutations in the dura cells on the proliferation of osteoblasts through the hippo/YAP mediated transcriptional regulation pathway.
Dong XH, Zhang MZ, Lai CZ, Li CC, Du L, Song GD, Zong XL, Jin XL
American journal of translational research 2021;13(10):11255-11270
American journal of translational research 2021;13(10):11255-11270
Identification and Validation of a Tumor Microenvironment-Related Gene Signature in Hepatocellular Carcinoma Prognosis.
Huang C, Zhang C, Sheng J, Wang D, Zhao Y, Qian L, Xie L, Meng Z
Frontiers in genetics 2021;12:717319
Frontiers in genetics 2021;12:717319
Identification of VWF as a Novel Biomarker in Lung Adenocarcinoma by Comprehensive Analysis.
He Y, Liu R, Yang M, Bi W, Zhou L, Zhang S, Jin J, Liang X, Zhang P
Frontiers in oncology 2021;11:639600
Frontiers in oncology 2021;11:639600
Exogenous H(2) S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
Zhang L, Jiang X, Liu N, Li M, Kang J, Chen L, Tang J, Dong S, Lu F, Zhang W
Journal of cellular and molecular medicine 2021 Sep;25(17):8201-8214
Journal of cellular and molecular medicine 2021 Sep;25(17):8201-8214
Biomimetic Cell-Substrate of Chitosan-Cross-linked Polyaniline Patterning on TiO(2) Nanotubes Enables hBM-MSCs to Differentiate the Osteoblast Cell Type.
Kandel R, Jang SR, Shrestha S, Lee SY, Shrestha BK, Park CH, Kim CS
ACS applied materials & interfaces 2021 Oct 6;13(39):47100-47117
ACS applied materials & interfaces 2021 Oct 6;13(39):47100-47117
Polydopamine-Coated Poly(l-lactide) Nanofibers with Controlled Release of VEGF and BMP-2 as a Regenerative Periosteum.
Sun H, Dong J, Wang Y, Shen S, Shi Y, Zhang L, Zhao J, Sun X, Jiang Q
ACS biomaterials science & engineering 2021 Oct 11;7(10):4883-4897
ACS biomaterials science & engineering 2021 Oct 11;7(10):4883-4897
Association of urinary ketamine and APOA1 levels with bladder dysfunction in ketamine abusers revealed via proteomics and targeted metabolite analyses.
Liu JC, Chen YT, Hsieh YJ, Wu CC, Huang MC, Hsu YC, Wu CT, Chen CK, Dash S, Yu JS
Scientific reports 2021 May 5;11(1):9583
Scientific reports 2021 May 5;11(1):9583
ET(A)R silencing ameliorated neurovascular injury after SAH in rats through ERK/KLF4-mediated phenotypic transformation of smooth muscle cells.
Zhang Z, Chen H, Liu L, Zhao G, He J, Liu H, Zhou C, Liu X, Sun X, Guo Z
Experimental neurology 2021 Mar;337:113596
Experimental neurology 2021 Mar;337:113596
Primary cilia regulate gastric cancer-induced bone loss via cilia/Wnt/β-catenin signaling pathway.
Xu J, Deng X, Wu X, Zhu H, Zhu Y, Liu J, Chen Q, Yuan C, Liu G, Wang C
Aging 2021 Mar 9;13(6):8989-9010
Aging 2021 Mar 9;13(6):8989-9010
Inactivation of SERCA2 Cys(674) accelerates aortic aneurysms by suppressing PPARγ.
Que Y, Shu X, Wang L, Wang S, Li S, Hu P, Tong X
British journal of pharmacology 2021 Jun;178(11):2305-2323
British journal of pharmacology 2021 Jun;178(11):2305-2323
Long-lasting renewable antibacterial porous polymeric coatings enable titanium biomaterials to prevent and treat peri-implant infection.
Wu S, Xu J, Zou L, Luo S, Yao R, Zheng B, Liang G, Wu D, Li Y
Nature communications 2021 Jun 3;12(1):3303
Nature communications 2021 Jun 3;12(1):3303
Nrf2 activation is involved in osteogenic differentiation of periodontal ligament stem cells under cyclic mechanical stretch.
Xi X, Zhao Y, Liu H, Li Z, Chen S, Liu D
Experimental cell research 2021 Jun 15;403(2):112598
Experimental cell research 2021 Jun 15;403(2):112598
The preventive and therapeutic effects of AAV1-KLF4-shRNA in cigarette smoke-induced pulmonary hypertension.
Sun D, Ding D, Li Q, Xie M, Xu Y, Liu X
Journal of cellular and molecular medicine 2021 Jan;25(2):1238-1251
Journal of cellular and molecular medicine 2021 Jan;25(2):1238-1251
A protumorigenic secretory pathway activated by p53 deficiency in lung adenocarcinoma.
Tan X, Shi L, Banerjee P, Liu X, Guo HF, Yu J, Bota-Rabassedas N, Rodriguez BL, Gibbons DL, Russell WK, Creighton CJ, Kurie JM
The Journal of clinical investigation 2021 Jan 4;131(1)
The Journal of clinical investigation 2021 Jan 4;131(1)
A Dual Role of Heme Oxygenase-1 in Angiotensin II-Induced Abdominal Aortic Aneurysm in the Normolipidemic Mice.
Kopacz A, Klóska D, Werner E, Hajduk K, Grochot-Przęczek A, Józkowicz A, Piechota-Polańczyk A
Cells 2021 Jan 15;10(1)
Cells 2021 Jan 15;10(1)
Significance of MR/OPN/HMGB1 axis in NAFLD-associated hepatic fibrogenesis.
Tang M, Jia H, Chen S, Yang B, Patpur BK, Song W, Chang Y, Li J, Yang C
Life sciences 2021 Jan 1;264:118619
Life sciences 2021 Jan 1;264:118619
lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.
Dai W, Wang M, Wang P, Wen J, Wang J, Cha S, Xiao X, He Y, Shu R, Bai D
International journal of molecular medicine 2021 Feb;47(2):607-620
International journal of molecular medicine 2021 Feb;47(2):607-620
Prostacyclin facilitates vascular smooth muscle cell phenotypic transformation via activating TP receptors when IP receptors are deficient.
Li Z, Luo W, Fang S, Chen X, Lin T, Zhou S, Zhang L, Yang W, Li Z, Ye J, Wang J, Liu P, Li Z
Acta physiologica (Oxford, England) 2021 Feb;231(2):e13555
Acta physiologica (Oxford, England) 2021 Feb;231(2):e13555
MSCs-extracellular vesicles attenuated neuroinflammation, synapse damage and microglial phagocytosis after hypoxia-ischemia injury by preventing osteopontin expression.
Xin D, Li T, Chu X, Ke H, Liu D, Wang Z
Pharmacological research 2021 Feb;164:105322
Pharmacological research 2021 Feb;164:105322
MicroRNA-520c-3p targeting of RelA/p65 suppresses atherosclerotic plaque formation.
Wang J, Hu X, Hu X, Gao F, Li M, Cui Y, Wei X, Qin Y, Zhang C, Zhao Y, Gao Y
The international journal of biochemistry & cell biology 2021 Feb;131:105873
The international journal of biochemistry & cell biology 2021 Feb;131:105873
Polypeptides IGF-1C and P24 synergistically promote osteogenic differentiation of bone marrow mesenchymal stem cells in vitro through the p38 and JNK signaling pathways.
Ran G, Fang W, Zhang L, Peng Y, Wu A, Li J, Ding X, Zeng S, He Y
The international journal of biochemistry & cell biology 2021 Dec;141:106091
The international journal of biochemistry & cell biology 2021 Dec;141:106091
Geniposide Ameliorated Dexamethasone-Induced Cholesterol Accumulation in Osteoblasts by Mediating the GLP-1R/ABCA1 Axis.
Zheng Y, Xiao Y, Zhang D, Zhang S, Ouyang J, Li L, Shi W, Zhang R, Liu H, Jin Q, Chen Z, Xu D, Wu L
Cells 2021 Dec 6;10(12)
Cells 2021 Dec 6;10(12)
Establishment and characterization of a highly metastatic human osteosarcoma cell line from osteosarcoma lung metastases.
Fan Z, Huang G, Zhao J, Li W, Lin T, Su Q, Yin J, Shen J
Journal of bone oncology 2021 Aug;29:100378
Journal of bone oncology 2021 Aug;29:100378
Polo Like Kinase 4 (PLK4) impairs human bone marrow mesenchymal stem cell (BMSC) viability and osteogenic differentiation.
Zhou B, Peng K, Wang G, Chen W, Kang Y
Biochemical and biophysical research communications 2021 Apr 16;549:221-228
Biochemical and biophysical research communications 2021 Apr 16;549:221-228
Higher BMP Expression in Tendon Stem/Progenitor Cells Contributes to the Increased Heterotopic Ossification in Achilles Tendon With Aging.
Dai G, Li Y, Liu J, Zhang C, Chen M, Lu P, Rui Y
Frontiers in cell and developmental biology 2020;8:570605
Frontiers in cell and developmental biology 2020;8:570605
Piperlongumine Attenuates High Calcium/Phosphate-Induced Arterial Calcification by Preserving P53/PTEN Signaling.
Shi W, Lu J, Li J, Qiu M, Lu Y, Gu J, Kong X, Sun W
Frontiers in cardiovascular medicine 2020;7:625215
Frontiers in cardiovascular medicine 2020;7:625215
Ethyl Acetate Fraction from Hedyotis diffusa plus Scutellaria barbata Suppresses Migration of Bone-Metastatic Breast Cancer Cells via OPN-FAK/ERK/NF-κB Axis.
Fang T, Yan YX, Yang Y, Lv YX, Chang QQ, Zhang DD
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3573240
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3573240
OPN Deficiency Increases the Severity of Osteoarthritis Associated with Aberrant Chondrocyte Senescence and Apoptosis and Upregulates the Expression of Osteoarthritis-Associated Genes.
Tian J, Cheng C, Kuang SD, Su C, Zhao X, Xiong YL, Li YS, Gao SG
Pain research & management 2020;2020:3428587
Pain research & management 2020;2020:3428587
R-Spondin 2 Induces Odontogenic Differentiation of Dental Pulp Stem/Progenitor Cells via Regulation of Wnt/β-Catenin Signaling.
Gong Y, Yuan S, Sun J, Wang Y, Liu S, Guo R, Dong W, Li R
Frontiers in physiology 2020;11:918
Frontiers in physiology 2020;11:918
Ginsenoside Rg3 attenuates ovariectomy-induced osteoporosis via AMPK/mTOR signaling pathway.
Zhang X, Huang F, Chen X, Wu X, Zhu J
Drug development research 2020 Nov;81(7):875-884
Drug development research 2020 Nov;81(7):875-884
RNA-seq analysis of palatal transcriptome changes in all-trans retinoic acid-induced cleft palate of mice.
Peng Y, Wang XH, Su CN, Qiao WW, Gao Q, Sun XF, Meng LY
Environmental toxicology and pharmacology 2020 Nov;80:103438
Environmental toxicology and pharmacology 2020 Nov;80:103438
TL1A inhibits atherosclerosis in apoE-deficient mice by regulating the phenotype of vascular smooth muscle cells.
Zhao D, Li J, Xue C, Feng K, Liu L, Zeng P, Wang X, Chen Y, Li L, Zhang Z, Duan Y, Han J, Yang X
The Journal of biological chemistry 2020 Nov 27;295(48):16314-16327
The Journal of biological chemistry 2020 Nov 27;295(48):16314-16327
Novel gene-specific translation mechanism of dysregulated, chronic inflammation reveals promising, multifaceted COVID-19 therapeutics.
Wang L, Muneer A, Xie L, Zhang F, Wu B, Mei L, Lenarcic EM, Feng EH, Song J, Xiong Y, Yu X, Wang C, Gheorghe C, Torralba K, Cook JG, Wan YY, Moorman NJ, Song H, Jin J, Chen X
bioRxiv : the preprint server for biology 2020 Nov 16;
bioRxiv : the preprint server for biology 2020 Nov 16;
T-cell death-associated gene 8 accelerates atherosclerosis by promoting vascular smooth muscle cell proliferation and migration.
Chen LD, Zhu WT, Cheng YY, Li ZH, Chen YQ, Yuan ZW, Lin CY, Jing DD, Liu ZQ, Yan PK
Atherosclerosis 2020 Mar;297:64-73
Atherosclerosis 2020 Mar;297:64-73
Exercise Promotes the Osteoinduction of HA/β-TCP Biomaterials via the Wnt Signaling Pathway.
Cheng L, Khalaf AT, Lin T, Ran L, Shi Z, Wan J, Zhou X, Zou L
Metabolites 2020 Mar 5;10(3)
Metabolites 2020 Mar 5;10(3)
Cortistatin ameliorates Ang II-induced proliferation of vascular smooth muscle cells by inhibiting autophagy through SSTR3 and SSTR5.
Wang Y, Zhang X, Chen W, Gao L, Li J, Song T, Chi J, Zhang X, Shi Z, Dong Y, Yin X, Liu Y
Life sciences 2020 Jul 15;253:117726
Life sciences 2020 Jul 15;253:117726
Quantitative alterations in bovine milk proteome from healthy, subclinical and clinical mastitis during S. aureus infection.
Maity S, Das D, Ambatipudi K
Journal of proteomics 2020 Jul 15;223:103815
Journal of proteomics 2020 Jul 15;223:103815
Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function.
Wang L, Yu P, Zhou B, Song J, Li Z, Zhang M, Guo G, Wang Y, Chen X, Han L, Hu S
Nature cell biology 2020 Jan;22(1):108-119
Nature cell biology 2020 Jan;22(1):108-119
The effect of extracellular matrix on the differentiation of mouse embryonic stem cells.
Ozdil B, Güler G, Acikgoz E, Kocaturk DC, Aktug H
Journal of cellular biochemistry 2020 Jan;121(1):269-283
Journal of cellular biochemistry 2020 Jan;121(1):269-283
SHED-derived conditioned exosomes enhance the osteogenic differentiation of PDLSCs via Wnt and BMP signaling in vitro.
Wang M, Li J, Ye Y, He S, Song J
Differentiation; research in biological diversity 2020 Jan-Feb;111:1-11
Differentiation; research in biological diversity 2020 Jan-Feb;111:1-11
Activation of cannabinoid receptor type 2-induced osteogenic differentiation involves autophagy induction and p62-mediated Nrf2 deactivation.
Xu A, Yang Y, Shao Y, Wu M, Sun Y
Cell communication and signaling : CCS 2020 Jan 15;18(1):9
Cell communication and signaling : CCS 2020 Jan 15;18(1):9
Modulation of the mechanosensing of mesenchymal stem cells by laser-induced patterning for the acceleration of tissue reconstruction through the Wnt/β-catenin signaling pathway activation.
Fu J, Liu X, Tan L, Cui Z, Liang Y, Li Z, Zhu S, Zheng Y, Kwok Yeung KW, Chu PK, Wu S
Acta biomaterialia 2020 Jan 1;101:152-167
Acta biomaterialia 2020 Jan 1;101:152-167
P38 MAPK signaling pathway mediates COM crystal-induced crystal adhesion change in rat renal tubular epithelial cells.
Qi S, Wang Q, Xie B, Chen Y, Zhang Z, Xu Y
Urolithiasis 2020 Feb;48(1):9-18
Urolithiasis 2020 Feb;48(1):9-18
Semaphorin 3A-hypoxia inducible factor 1 subunit alpha co-overexpression enhances the osteogenic differentiation of induced pluripotent stem cells-derived mesenchymal stem cells in vitro.
Li JY, Wang TT, Li C, Wang ZF, Li S, Ma L, Zheng LL
Chinese medical journal 2020 Feb 5;133(3):301-309
Chinese medical journal 2020 Feb 5;133(3):301-309
PKM2 suppresses osteogenesis and facilitates adipogenesis by regulating β-catenin signaling and mitochondrial fusion and fission.
Guo J, Ren R, Yao X, Ye Y, Sun K, Lin J, Wang G, Guo F, Xiao J, Xu T
Aging 2020 Feb 25;12(4):3976-3992
Aging 2020 Feb 25;12(4):3976-3992
Sustained delivery of PlGF-2(123-144*)-fused BMP2-related peptide P28 from small intestinal submucosa/polylactic acid scaffold material for bone tissue regeneration.
Xiong Z, Cui W, Sun T, Teng Y, Qu Y, Yang L, Zhou J, Chen K, Yao S, Shao Z, Guo X
RSC advances 2020 Feb 13;10(12):7289-7300
RSC advances 2020 Feb 13;10(12):7289-7300
Daphnetin ameliorates glucocorticoid-induced osteoporosis via activation of Wnt/GSK-3β/β-catenin signaling.
Wang Y, Chen J, Chen J, Dong C, Yan X, Zhu Z, Lu P, Song Z, Liu H, Chen S
Toxicology and applied pharmacology 2020 Dec 15;409:115333
Toxicology and applied pharmacology 2020 Dec 15;409:115333
Smooth muscle NADPH oxidase 4 promotes angiotensin II-induced aortic aneurysm and atherosclerosis by regulating osteopontin.
Yu W, Xiao L, Que Y, Li S, Chen L, Hu P, Xiong R, Seta F, Chen H, Tong X
Biochimica et biophysica acta. Molecular basis of disease 2020 Dec 1;1866(12):165912
Biochimica et biophysica acta. Molecular basis of disease 2020 Dec 1;1866(12):165912
Biomineralizaion of hydroxyapatite on polyethylene terephthalate artificial ligaments promotes graft-bone healing after anterior cruciate ligament reconstruction: An in vitro and in vivo study.
Cai J, Ai C, Chen J, Chen S
Journal of biomaterials applications 2020 Aug;35(2):193-204
Journal of biomaterials applications 2020 Aug;35(2):193-204
AKT/FOXO1 axis links cross-talking of endothelial cell and pericyte in TIE2-mutated venous malformations.
Si Y, Huang J, Li X, Fu Y, Xu R, Du Y, Cheng J, Jiang H
Cell communication and signaling : CCS 2020 Aug 31;18(1):139
Cell communication and signaling : CCS 2020 Aug 31;18(1):139
Effect of interleukin-33 on cementoblast-mediated cementum repair during orthodontic tooth movement.
Dong X, Feng J, Wen J, Bai D, Xu H
Archives of oral biology 2020 Apr;112:104663
Archives of oral biology 2020 Apr;112:104663
A novel Sprouty4-ERK1/2-Wnt/β-catenin regulatory loop in marrow stromal progenitor cells controls osteogenic and adipogenic differentiation.
Tian L, Xiao H, Li M, Wu X, Xie Y, Zhou J, Zhang X, Wang B
Metabolism: clinical and experimental 2020 Apr;105:154189
Metabolism: clinical and experimental 2020 Apr;105:154189
Excessive Methionine Supplementation Exacerbates the Development of Abdominal Aortic Aneurysm in Rats.
Fan Y, Li N, Liu C, Dong H, Hu X
Journal of vascular research 2019;56(5):230-240
Journal of vascular research 2019;56(5):230-240
Icariin Protects Bone Marrow Mesenchymal Stem Cells Against Iron Overload Induced Dysfunction Through Mitochondrial Fusion and Fission, PI3K/AKT/mTOR and MAPK Pathways.
Yao X, Jing X, Guo J, Sun K, Deng Y, Zhang Y, Guo F, Ye Y
Frontiers in pharmacology 2019;10:163
Frontiers in pharmacology 2019;10:163
2,3,7,8-Tetrachlorodibenzo-p-dioxin promotes injury-induced vascular neointima formation in mice.
Guo S, Zhang R, Liu Q, Wan Q, Wang Y, Yu Y, Liu G, Shen Y, Yu Y, Zhang J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10207-10217
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10207-10217
Inhibiting effect of microRNA-187-3p on osteogenic differentiation of osteoblast precursor cells by suppressing cannabinoid receptor type 2.
Xu A, Yang Y, Shao Y, Wu M, Sun Y
Differentiation; research in biological diversity 2019 Sep-Oct;109:9-15
Differentiation; research in biological diversity 2019 Sep-Oct;109:9-15
[Down-regulation of miR-381-3p inhibits osteogenic differentiation of mouse embryonic palatal mesenchymal cells in 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-induced cleft palate of fetal mice].
Jiang H, Yuan X, Fu Y
Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 2019 Sep 15;33(9):1174-1180
Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 2019 Sep 15;33(9):1174-1180
Incorporated-bFGF polycaprolactone/polyvinylidene fluoride nanocomposite scaffold promotes human induced pluripotent stem cells osteogenic differentiation.
Abazari MF, Soleimanifar F, Enderami SE, Nematzadeh M, Nasiri N, Nejati F, Saburi E, Khodashenas S, Darbasizadeh B, Khani MM, Ghoraeian P
Journal of cellular biochemistry 2019 Oct;120(10):16750-16759
Journal of cellular biochemistry 2019 Oct;120(10):16750-16759
SPARC induces phenotypic modulation of human brain vascular smooth muscle cells via AMPK/mTOR-mediated autophagy.
Li T, Tan X, Zhu S, Zhong W, Huang B, Sun J, Li F, Wang Y
Neuroscience letters 2019 Nov 1;712:134485
Neuroscience letters 2019 Nov 1;712:134485
Osteopontin in the Pathogenesis of Aortic Dissection by the Enhancement of MMP Expressions.
Fan F, Zhou Q, Xu Z, Wang D
International heart journal 2019 Mar 20;60(2):429-435
International heart journal 2019 Mar 20;60(2):429-435
Citric acid enhances the physical properties, cytocompatibility and osteogenesis of magnesium calcium phosphate cement.
Wang S, Xu C, Yu S, Wu X, Jie Z, Dai H
Journal of the mechanical behavior of biomedical materials 2019 Jun;94:42-50
Journal of the mechanical behavior of biomedical materials 2019 Jun;94:42-50
The role and mechanism of transforming growth factor beta 3 in human myocardial infarction-induced myocardial fibrosis.
Xue K, Zhang J, Li C, Li J, Wang C, Zhang Q, Chen X, Yu X, Sun L, Yu X
Journal of cellular and molecular medicine 2019 Jun;23(6):4229-4243
Journal of cellular and molecular medicine 2019 Jun;23(6):4229-4243
Small molecule inhibitor of TGF-β signaling enables robust osteogenesis of autologous GMSCs to successfully repair minipig severe maxillofacial bone defects.
Shi A, Heinayati A, Bao D, Liu H, Ding X, Tong X, Wang L, Wang B, Qin H
Stem cell research & therapy 2019 Jun 13;10(1):172
Stem cell research & therapy 2019 Jun 13;10(1):172
Adipose-derived stem cells-conditioned medium improved osteogenic differentiation of induced pluripotent stem cells when grown on polycaprolactone nanofibers.
Soleimanifar F, Hosseini FS, Atabati H, Behdari A, Kabiri L, Enderami SE, Khani MM, Ardeshirylajimi A, Saburi E
Journal of cellular physiology 2019 Jul;234(7):10315-10323
Journal of cellular physiology 2019 Jul;234(7):10315-10323
Peroxisome Proliferator-Activated Receptor-γ Coactivator-1α Inhibits Vascular Calcification Through Sirtuin 3-Mediated Reduction of Mitochondrial Oxidative Stress.
Feng H, Wang JY, Yu B, Cong X, Zhang WG, Li L, Liu LM, Zhou Y, Zhang CL, Gu PL, Wu LL
Antioxidants & redox signaling 2019 Jul 1;31(1):75-91
Antioxidants & redox signaling 2019 Jul 1;31(1):75-91
Circulating osteopontin per tumor volume as a prognostic biomarker for resectable intrahepatic cholangiocarcinoma.
Zhou KQ, Liu WF, Yang LX, Sun YF, Hu J, Chen FY, Zhou C, Zhang XY, Peng YF, Yu L, Zhou J, Fan J, Wang Z
Hepatobiliary surgery and nutrition 2019 Dec;8(6):582-596
Hepatobiliary surgery and nutrition 2019 Dec;8(6):582-596
Effect of Hydroxyapatite Nanorods on the Fate of Human Adipose-Derived Stem Cells Assessed In Situ at the Single Cell Level with a High-Throughput, Real-Time Microfluidic Chip.
Hao M, He J, Wang C, Wang C, Ma B, Zhang S, Duan J, Liu F, Zhang Y, Han L, Liu H, Sang Y
Small (Weinheim an der Bergstrasse, Germany) 2019 Dec;15(51):e1905001
Small (Weinheim an der Bergstrasse, Germany) 2019 Dec;15(51):e1905001
Study of Bone Regeneration and Osteointegration Effect of a Novel Selective Laser-Melted Titanium-Tantalum-Niobium-Zirconium Alloy Scaffold.
Guo Y, Wu J, Xie K, Tan J, Yang Y, Zhao S, Wang L, Jiang W, Hao Y
ACS biomaterials science & engineering 2019 Dec 9;5(12):6463-6473
ACS biomaterials science & engineering 2019 Dec 9;5(12):6463-6473
Efficient osteogenic differentiation of the dental pulp stem cells on β-glycerophosphate loaded polycaprolactone/polyethylene oxide blend nanofibers.
Hosseini FS, Enderami SE, Hadian A, Abazari MF, Ardeshirylajimi A, Saburi E, Soleimanifar F, Nazemisalman B
Journal of cellular physiology 2019 Aug;234(8):13951-13958
Journal of cellular physiology 2019 Aug;234(8):13951-13958
Quantitative proteomics of milk whey reveals breed and season specific variation in protein abundance in Holstein Friesian cow and Murrah buffalo.
Maity S, Ambatipudi K
Research in veterinary science 2019 Aug;125:244-252
Research in veterinary science 2019 Aug;125:244-252
Effect of microRNA-21 on hypoxia-inducible factor-1α in orthodontic tooth movement and human periodontal ligament cells under hypoxia.
Zhang X, Chen D, Zheng J, Deng L, Chen Z, Ling J, Wu L
Experimental and therapeutic medicine 2019 Apr;17(4):2830-2836
Experimental and therapeutic medicine 2019 Apr;17(4):2830-2836
Promoting osteogenic differentiation of human-induced pluripotent stem cells by releasing Wnt/β-catenin signaling activator from the nanofibers.
Hosseini FS, Soleimanifar F, Khojasteh A, Ardeshirylajimi A
Journal of cellular biochemistry 2019 Apr;120(4):6339-6346
Journal of cellular biochemistry 2019 Apr;120(4):6339-6346
Validation of Phosphodiesterase-10 as a Novel Target for Pulmonary Arterial Hypertension via Highly Selective and Subnanomolar Inhibitors.
Huang YY, Yu YF, Zhang C, Chen Y, Zhou Q, Li Z, Zhou S, Li Z, Guo L, Wu D, Wu Y, Luo HB
Journal of medicinal chemistry 2019 Apr 11;62(7):3707-3721
Journal of medicinal chemistry 2019 Apr 11;62(7):3707-3721
New Application of Psoralen and Angelicin on Periodontitis With Anti-bacterial, Anti-inflammatory, and Osteogenesis Effects.
Li X, Yu C, Hu Y, Xia X, Liao Y, Zhang J, Chen H, Lu W, Zhou W, Song Z
Frontiers in cellular and infection microbiology 2018;8:178
Frontiers in cellular and infection microbiology 2018;8:178
Downregulated Expression of Solute Carrier Family 26 Member 6 in NRK-52E Cells Attenuates Oxalate-Induced Intracellular Oxidative Stress.
Jiang H, Gao X, Gong J, Yang Q, Lan R, Wang T, Liu J, Yin C, Wang S, Liu Z
Oxidative medicine and cellular longevity 2018;2018:1724648
Oxidative medicine and cellular longevity 2018;2018:1724648
Osteopontin is essential for IL-1β production and apoptosis in peri-implantitis.
Che C, Liu J, Yang J, Ma L, Bai N, Zhang Q
Clinical implant dentistry and related research 2018 Jun;20(3):384-392
Clinical implant dentistry and related research 2018 Jun;20(3):384-392
Hypoxia-Inducible Factor-1α (HIF-1α) Expression on Endothelial Cells in Juvenile Nasopharyngeal Angiofibroma: A Review of 70 cases and Tissue Microarray Analysis.
Song X, Yang C, Zhang H, Wang J, Sun X, Hu L, Liu Z, Wang D
The Annals of otology, rhinology, and laryngology 2018 Jun;127(6):357-366
The Annals of otology, rhinology, and laryngology 2018 Jun;127(6):357-366
Nesfatin-1 promotes VSMC migration and neointimal hyperplasia by upregulating matrix metalloproteinases and downregulating PPARγ.
Zhang JR, Lu QB, Feng WB, Wang HP, Tang ZH, Cheng H, Du Q, Wang YB, Li KX, Sun HJ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:711-717
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:711-717
Negative pressure wound therapy promotes muscle-derived stem cell osteogenic differentiation through MAPK pathway.
Liu H, Zheng X, Chen L, Jian C, Hu X, Zhao Y, Li Z, Yu A
Journal of cellular and molecular medicine 2018 Jan;22(1):511-520
Journal of cellular and molecular medicine 2018 Jan;22(1):511-520
Teniposide regulates the phenotype switching of vascular smooth muscle cells in a miR-21-dependent manner.
Han H, Yang S, Liang Y, Zeng P, Liu L, Yang X, Duan Y, Han J, Chen Y
Biochemical and biophysical research communications 2018 Dec 2;506(4):1040-1046
Biochemical and biophysical research communications 2018 Dec 2;506(4):1040-1046
Myricetin ameliorates glucocorticoid-induced osteoporosis through the ERK signaling pathway.
Fan S, Gao X, Chen P, Li X
Life sciences 2018 Aug 15;207:205-211
Life sciences 2018 Aug 15;207:205-211
Osteopontin contributes to effective neutrophil recruitment, IL-1β production and apoptosis in Aspergillus fumigatus keratitis.
Zhao G, Hu M, Li C, Lee J, Yuan K, Zhu G, Che C
Immunology and cell biology 2018 Apr;96(4):401-412
Immunology and cell biology 2018 Apr;96(4):401-412
The prognostic value of osteopontin in limited-stage small cell lung cancer patients and its mechanism.
Liu F, Bai C, Guo Z
Oncotarget 2017 Sep 19;8(41):70084-70096
Oncotarget 2017 Sep 19;8(41):70084-70096
The protective effect of PFTα on alcohol-induced osteonecrosis of the femoral head.
Chen YX, Zhu DY, Yin JH, Yin WJ, Zhang YL, Ding H, Yu XW, Mei J, Gao YS, Zhang CQ
Oncotarget 2017 Nov 21;8(59):100691-100707
Oncotarget 2017 Nov 21;8(59):100691-100707
MgAl layered double hydroxide/chitosan porous scaffolds loaded with PFTα to promote bone regeneration.
Chen YX, Zhu R, Ke QF, Gao YS, Zhang CQ, Guo YP
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse kidney tissue were subjected to SDS PAGE followed by western blot with 22952-1-AP( OPN, SPP1 Antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human stomach cancer using 22952-1-AP(OPN, SPP1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Osteopontin antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human Osteopontin. This antibody recognizes human, mouse antigen. The Osteopontin antibody has been validated for the following applications: ELISA, IHC, WB analysis.
