Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- NB100-2136 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-2136, RRID:AB_10001620
- Product name
- Rabbit Polyclonal CDX2 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 ul
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C. Do not freeze.
Submitted references Patient-Derived Organoids Predict Chemoradiation Responses of Locally Advanced Rectal Cancer.
Prognostic value of low CDX2 expression in colorectal cancers with a high stromal content - a short report.
Practical and Robust Identification of Molecular Subtypes in Colorectal Cancer by Immunohistochemistry.
Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions.
Transcriptional networks driving enhancer function in the CFTR gene.
Essential and redundant functions of caudal family proteins in activating adult intestinal genes.
TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions.
Yao Y, Xu X, Yang L, Zhu J, Wan J, Shen L, Xia F, Fu G, Deng Y, Pan M, Guo Q, Gao X, Li Y, Rao X, Zhou Y, Liang L, Wang Y, Zhang J, Zhang H, Li G, Zhang L, Peng J, Cai S, Hu C, Gao J, Clevers H, Zhang Z, Hua G
Cell stem cell 2020 Jan 2;26(1):17-26.e6
Cell stem cell 2020 Jan 2;26(1):17-26.e6
Prognostic value of low CDX2 expression in colorectal cancers with a high stromal content - a short report.
Sandberg TP, Sweere I, van Pelt GW, Putter H, Vermeulen L, Kuppen PJ, Tollenaar RAEM, Mesker WE
Cellular oncology (Dordrecht) 2019 Jun;42(3):397-403
Cellular oncology (Dordrecht) 2019 Jun;42(3):397-403
Practical and Robust Identification of Molecular Subtypes in Colorectal Cancer by Immunohistochemistry.
Trinh A, Trumpi K, De Sousa E Melo F, Wang X, de Jong JH, Fessler E, Kuppen PJ, Reimers MS, Swets M, Koopman M, Nagtegaal ID, Jansen M, Hooijer GK, Offerhaus GJ, Kranenburg O, Punt CJ, Medema JP, Markowetz F, Vermeulen L
Clinical cancer research : an official journal of the American Association for Cancer Research 2017 Jan 15;23(2):387-398
Clinical cancer research : an official journal of the American Association for Cancer Research 2017 Jan 15;23(2):387-398
Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions.
De Sousa E Melo F, Wang X, Jansen M, Fessler E, Trinh A, de Rooij LP, de Jong JH, de Boer OJ, van Leersum R, Bijlsma MF, Rodermond H, van der Heijden M, van Noesel CJ, Tuynman JB, Dekker E, Markowetz F, Medema JP, Vermeulen L
Nature medicine 2013 May;19(5):614-8
Nature medicine 2013 May;19(5):614-8
Transcriptional networks driving enhancer function in the CFTR gene.
Kerschner JL, Harris A
The Biochemical journal 2012 Sep 1;446(2):203-12
The Biochemical journal 2012 Sep 1;446(2):203-12
Essential and redundant functions of caudal family proteins in activating adult intestinal genes.
Verzi MP, Shin H, Ho LL, Liu XS, Shivdasani RA
Molecular and cellular biology 2011 May;31(10):2026-39
Molecular and cellular biology 2011 May;31(10):2026-39
TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions.
Verzi MP, Hatzis P, Sulahian R, Philips J, Schuijers J, Shin H, Freed E, Lynch JP, Dang DT, Brown M, Clevers H, Liu XS, Shivdasani RA
Proceedings of the National Academy of Sciences of the United States of America 2010 Aug 24;107(34):15157-62
Proceedings of the National Academy of Sciences of the United States of America 2010 Aug 24;107(34):15157-62
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunoprecipitation: CDX2 Antibody [NB100-2136] - Detection of Human CDX2 on HeLa whole cell lysate using NB100-2136. CDX2 was also immunoprecipitated by rabbit anti-CDX2 antibody NB100-2137 using 3 mcg/mg lysate.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CDX2 Antibody [NB100-2136] - FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-CDX2 used at a dilution of 1:1,000 (1ug/ml). Detection: DAB