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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Immunohistochemistry [1]
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- Product number
- ABIN358936 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Tuberous Sclerosis 2 (TSC2) (Ser1798) antibody
- Antibody type
- Polyclonal
- Antigen
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S1798 of human TSC2.
- Description
- Protein A column, followed by peptide affinity purification
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- Ser1798
- Vial size
- 0.4 mL
- Concentration
- 0.25 mg/mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity.
Tuberous sclerosis complex 2 gene product interacts with human SMAD proteins. A molecular link of two tumor suppressor pathways.
Regulation of B-Raf kinase activity by tuberin and Rheb is mammalian target of rapamycin (mTOR)-independent.
Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome.
Li Y, Inoki K, Guan KL
Molecular and cellular biology 2004 Sep;24(18):7965-75
Molecular and cellular biology 2004 Sep;24(18):7965-75
Tuberous sclerosis complex 2 gene product interacts with human SMAD proteins. A molecular link of two tumor suppressor pathways.
Birchenall-Roberts MC, Fu T, Bang OS, Dambach M, Resau JH, Sadowski CL, Bertolette DC, Lee HJ, Kim SJ, Ruscetti FW
The Journal of biological chemistry 2004 Jun 11;279(24):25605-13
The Journal of biological chemistry 2004 Jun 11;279(24):25605-13
Regulation of B-Raf kinase activity by tuberin and Rheb is mammalian target of rapamycin (mTOR)-independent.
Karbowniczek M, Cash T, Cheung M, Robertson GP, Astrinidis A, Henske EP
The Journal of biological chemistry 2004 Jul 16;279(29):29930-7
The Journal of biological chemistry 2004 Jul 16;279(29):29930-7
Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome.
Corradetti MN, Inoki K, Bardeesy N, DePinho RA, Guan KL
Genes & development 2004 Jul 1;18(13):1533-8
Genes & development 2004 Jul 1;18(13):1533-8
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with TSC2 Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
