Antibody data
- Antibody Data
- Antigen structure
- References [93]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
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- Product number
- 10458-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10458-1-AP, RRID:AB_2250289
- Product name
- Myelin basic protein antibody
- Antibody type
- Polyclonal
- Description
- Myelin basic protein antibody (Cat. #10458-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Hypoxic Bone Mesenchymal Stem Cell-Derived Exosomes Direct Schwann Cells Proliferation, Migration, and Paracrine to Accelerate Facial Nerve Regeneration via circRNA_Nkd2/miR-214-3p/MED19 Axis.
Microglia aggravate white matter injury via C3/C3aR pathway after experimental subarachnoid hemorrhage.
Construction of functional neural network tissue combining CBD-NT3-modified linear-ordered collagen scaffold and TrkC-modified iPSC-derived neural stem cells for spinal cord injury repair.
Nerve Guide Conduits Integrated with Fisetin-Loaded Chitosan Hydrogels for Reducing Oxidative Stress, Inflammation, and Nerve Regeneration.
Conditioned medium from human dental pulp stem cells treats spinal cord injury by inhibiting microglial pyroptosis.
Protective effect of alirocumab, a PCSK9 inhibitor, on the sciatic nerve of rats with diabetic peripheral neuropathy.
Enhancing axonal myelination: Clemastine attenuates cognitive impairment in a rat model of diffuse traumatic brain injury.
Exogenous NADPH could mitigate pyroptosis-induced brain injury in fetal mice exposed to gestational intermittent hypoxia.
Selective bioaccumulation of polystyrene nanoplastics in fetal rat brain and damage to myelin development.
Circadian misalignment impairs oligodendrocyte myelination via Bmal1 overexpression leading to anxiety and depression-like behaviors.
Matrine Mediated Immune Protection in MS by Regulating Gut Microbiota and Production of SCFAs.
Clemastine-induced enhancement of hippocampal myelination alleviates memory impairment in mice with chronic pain.
A High MCT-Based Ketogenic Diet Suppresses Th1 and Th17 Responses to Ameliorate Experimental Autoimmune Encephalomyelitis in Mice by Inhibiting GSDMD and JAK2-STAT3/4 Pathways.
Targeting Ferroptosis Promotes Functional Recovery by Mitigating White Matter Injury Following Acute Carbon Monoxide Poisoning.
Sevoflurane causes cognitive impairment by inducing iron deficiency and inhibiting the proliferation of neural precursor cells in infant mice.
Combining PLGA microspheres loaded with Liver X receptor agonist GW3965 with a chitosan nerve conduit can promote the healing and regeneration of the wounded sciatic nerve.
Complanatuside A improves functional recovery after spinal cord injury through inhibiting JNK signaling-mediated microglial activation.
Antidepressant effect of teriflunomide via oligodendrocyte protection in a mouse model.
Sildenafil Enhances the Therapeutic Effect of Islet Transplantation for Diabetic Peripheral Neuropathy via mTOR/S6K1 Pathway.
The neuroprotective effect of dl-3-n-butylphthalide on the brain with experimental intracerebral hemorrhage.
Engineered extracellular vesicles for delivery of siRNA promoting targeted repair of traumatic spinal cord injury.
Bone marrow mesenchymal stem cells and exercise restore motor function following spinal cord injury by activating PI3K/AKT/mTOR pathway.
Brain-Derived Estrogen Regulates Neurogenesis, Learning and Memory with Aging in Female Rats.
Mesenchymal stem cells transplantation combined with IronQ attenuates ICH-induced inflammation response via Mincle/syk signaling pathway.
Baicalin facilitates remyelination and suppresses neuroinflammation in rats with chronic cerebral hypoperfusion by activating Wnt/β-catenin and inhibiting NF-κB signaling.
Neuroprotective effect of aloe emodin against Huntington's disease-like symptoms in R6/1 transgenic mice.
Macrophage lineage cells-derived migrasomes activate complement-dependent blood-brain barrier damage in cerebral amyloid angiopathy mouse model.
Sigma-1 Receptor Activation Improves Oligodendrogenesis and Promotes White-Matter Integrity after Stroke in Mice with Diabetic Mellitus.
Spatial and temporal alterations of developing oligodendrocytes induced by repeated sevoflurane exposure in neonatal mice.
Remyelination in neuromyelitis optica spectrum disorder is promoted by edaravone through mTORC1 signaling activation.
Jatrorrhizine ameliorates Schwann cell myelination via inhibiting HDAC3 ability to recruit Atxn2l for regulating the NRG1-ErbB2-PI3K-AKT pathway in diabetic peripheral neuropathy mice.
Erythrocyte Plasma Membrane Lipid Composition Mirrors That of Neurons and Glial Cells in Murine Experimental In Vitro and In Vivo Inflammation.
Supramolecular Hydrogel Microspheres of Platelet-Derived Growth Factor Mimetic Peptide Promote Recovery from Spinal Cord Injury.
Insulin-like Growth Factor-1 Prevents Hypoxia/Reoxygenation-Induced White Matter Injury in Sickle Cell Mice.
Rapamycin Exerts an Antidepressant Effect and Enhances Myelination in the Prefrontal Cortex of Chronic Restraint Stress Mice.
Neuron-Derived Exosomes Promote the Recovery of Spinal Cord Injury by Modulating Nerve Cells in the Cellular Microenvironment of the Lesion Area.
Ropivacaine microsphere-loaded electroconductive nerve dressings for long-acting analgesia and functional recovery following diabetic peripheral nerve injury.
Nattokinase Promotes Post-stroke Neurogenesis and Cognition Recovery via Increasing Circulating Irisin.
Apolipoprotein E Polymorphism Impacts White Matter Injury Through Microglial Phagocytosis After Experimental Subarachnoid Hemorrhage.
Lipid-accumulated reactive astrocytes promote disease progression in epilepsy.
FOXP3+ macrophage represses acute ischemic stroke-induced neural inflammation.
Catalpol Regulates Oligodendrocyte Regeneration and Remyelination by Activating the GEF-Cdc42/Rac1 Signaling Pathway in EAE Mice.
ADSCs Combined with Melatonin Promote Peripheral Nerve Regeneration through Autophagy.
Behavioral and Molecular Consequences of Chronic Sleep Restriction During Development in Fragile X Mice.
Effect of β-hydroxybutyrate on behavioral alterations, molecular and morphological changes in CNS of multiple sclerosis mouse model.
Novel recombinant protein flagellin A N/C attenuates experimental autoimmune encephalomyelitis by suppressing the ROS/NF-κB/NLRP3 signaling pathway.
Delivery of Basic Fibroblast Growth Factor Through an In Situ Forming Smart Hydrogel Activates Autophagy in Schwann Cells and Improves Facial Nerves Generation via the PAK-1 Signaling Pathway.
Enhanced effect of combining bone marrow mesenchymal stem cells (BMMSCs) and pulsed electromagnetic fields (PEMF) to promote recovery after spinal cord injury in mice.
HDAC3 Inhibitor RGFP966 Ameliorated Neuroinflammation in the Cuprizone-Induced Demyelinating Mouse Model and LPS-Stimulated BV2 Cells by Downregulating the P2X7R/STAT3/NF-κB65/NLRP3 Activation.
Stemazole Promotes Oligodendrocyte Precursor Cell Survival In Vitro and Remyelination In Vivo.
Ginsenoside Rg1 promotes remyelination and functional recovery in demyelinating disease by enhancing oligodendrocyte precursor cells-mediated myelin repair.
The divergent effects of astrocyte ceruloplasmin on learning and memory function in young and old mice.
Neutrophil Nanovesicle Protects against Experimental Autoimmune Encephalomyelitis through Enhancing Myelin Clearance by Microglia.
Expression and immunogenicity of nsp10 protein of porcine epidemic diarrhea virus.
E3 ubiquitin ligase Triad1 promotes neuronal apoptosis by regulating the p53-caspase3 pathway after spinal cord injury.
SPIONs mediated magnetic actuation promotes nerve regeneration by inducing and maintaining repair-supportive phenotypes in Schwann cells.
Development of a Chemical Cocktail That Rescues Mouse Brain Demyelination in a Cuprizone-Induced Model.
Sensory neurons have an axon initial segment that initiates spontaneous activity in neuropathic pain.
C1q inhibits differentiation of oligodendrocyte progenitor cells via Wnt/β-catenin signaling activation in a cuprizone-induced mouse model of multiple sclerosis.
Rewired glycosylation activity promotes scarless regeneration and functional recovery in spiny mice after complete spinal cord transection.
Preparation, Characterization, Evaluation of Neuroprotective Effect, and Related Mechanisms of Phosphatidylserine Emulsion in 5- and 12-Week Old Mice.
Dose optimization of intrathecal administration of human umbilical cord mesenchymal stem cells for the treatment of subacute incomplete spinal cord injury.
An in vivo implementation of the MEX MRI for myelin fraction of mice brain.
Multifunctional biomimetic hydrogel based on graphene nanoparticles and sodium alginate for peripheral nerve injury therapy.
The microbiota-gut-brain axis participates in chronic cerebral hypoperfusion by disrupting the metabolism of short-chain fatty acids.
Photobiomodulation Therapy Attenuates Anxious-Depressive-Like Behavior in the TgF344 Rat Model.
Connexin43 promotes angiogenesis through activating the HIF-1α/VEGF signaling pathway under chronic cerebral hypoperfusion.
Transfer of α-synuclein from neurons to oligodendrocytes triggers myelin sheath destruction in methamphetamine administration mice.
Maternal high sugar and fat diet benefits offspring brain function via targeting on the gut-brain axis.
A five-m6A regulatory gene signature is a prognostic biomarker in lung adenocarcinoma patients.
A Novel Rat Model with Long Range Optic Nerve Injury to Study Retinal Ganglion Cells Endogenous Regeneration.
Evaluation of cytokines and structural proteins to analyze the pathology of febrile central nervous system disease.
Intranasal administration of DHED protects against exhaustive exercise-induced brain injury in rats.
Caffeic Acid Phenethyl Ester Protects against Experimental Autoimmune Encephalomyelitis by Regulating T Cell Activities.
Acupuncture Improves White Matter Perfusion and Integrity in Rat Model of Vascular Dementia: An MRI-Based Imaging Study.
Bixin Attenuates Experimental Autoimmune Encephalomyelitis by Suppressing TXNIP/NLRP3 Inflammasome Activity and Activating NRF2 Signaling.
The combined treatment of NAD(+) and atorvastatin ameliorates the development of experimental autoimmune encephalomyelitis in C57BL/6 mice.
Subarachnoid transplantation of human umbilical cord mesenchymal stem cell in rodent model with subacute incomplete spinal cord injury: Preclinical safety and efficacy study.
Deficiency of microglial Hv1 channel is associated with activation of autophagic pathway and ROS production in LPC-induced demyelination mouse model.
Sevoflurane anesthesia during pregnancy in mice induces cognitive impairment in the offspring by causing iron deficiency and inhibiting myelinogenesis.
Arsenic trioxide ameliorates experimental autoimmune encephalomyelitis in C57BL/6 mice by inducing CD4(+) T cell apoptosis.
Triclosan induces zebrafish neurotoxicity by abnormal expression of miR-219 targeting oligodendrocyte differentiation of central nervous system.
Amelioration of clinical course and demyelination in the cuprizone mouse model in relation to ketogenic diet.
Chronic Sleep Restriction in Developing Male Mice Results in Long Lasting Behavior Impairments.
Myelin Oligodendrocyte Glycoprotein-IgG Contributes to Oligodendrocytopathy in the Presence of Complement, Distinct from Astrocytopathy Induced by AQP4-IgG.
Integral membrane protein 2A inhibits cell growth in human breast cancer via enhancing autophagy induction.
Mesenchymal Stem Cell-Derived Exosomes Reduce A1 Astrocytes via Downregulation of Phosphorylated NFκB P65 Subunit in Spinal Cord Injury.
Sigma-1 receptor activation alleviates blood-brain barrier dysfunction in vascular dementia mice.
Structural and visual functional deficits in a rat model of neuromyelitis optica spectrum disorders related optic neuritis.
ST8SIA2 promotes oligodendrocyte differentiation and the integrity of myelin and axons.
Protective Effect of 17β-Estradiol Upon Hippocampal Spine Density and Cognitive Function in an Animal Model of Vascular Dementia.
Treatment with NAD(+) inhibited experimental autoimmune encephalomyelitis by activating AMPK/SIRT1 signaling pathway and modulating Th1/Th17 immune responses in mice.
Methylene blue alleviates experimental autoimmune encephalomyelitis by modulating AMPK/SIRT1 signaling pathway and Th17/Treg immune response.
Wang H, Zhao H, Chen Z, Cai X, Wang X, Zhou P, Tang Y, Ying T, Zhang X, Shen Y, Wang B, Zhu W, Zhu J, Wang X, Li S
International journal of nanomedicine 2024;19:1409-1429
International journal of nanomedicine 2024;19:1409-1429
Microglia aggravate white matter injury via C3/C3aR pathway after experimental subarachnoid hemorrhage.
Yang L, Wu J, Zhang F, Zhang L, Zhang X, Zhou J, Pang J, Xie B, Xie H, Jiang Y, Peng J
Experimental neurology 2024 Sep;379:114853
Experimental neurology 2024 Sep;379:114853
Construction of functional neural network tissue combining CBD-NT3-modified linear-ordered collagen scaffold and TrkC-modified iPSC-derived neural stem cells for spinal cord injury repair.
Wu Z, Zhou Y, Hou X, Liu W, Yin W, Wang L, Cao Y, Jiang Z, Guo Y, Chen Q, Xie W, Wang Z, Shi N, Liu Y, Gao X, Luo L, Dai J, Ren C, Jiang X
Bioactive materials 2024 May;35:242-258
Bioactive materials 2024 May;35:242-258
Nerve Guide Conduits Integrated with Fisetin-Loaded Chitosan Hydrogels for Reducing Oxidative Stress, Inflammation, and Nerve Regeneration.
Fang J, Xu B, Jin X, Chen F, Liu S, Liu S, Wang S, Zhang F, Song K, Wang J, Nan L, Liu J
Macromolecular bioscience 2024 May;24(5):e2300476
Macromolecular bioscience 2024 May;24(5):e2300476
Conditioned medium from human dental pulp stem cells treats spinal cord injury by inhibiting microglial pyroptosis.
Liu T, Ma Z, Liu L, Pei Y, Wu Q, Xu S, Liu Y, Ding N, Guan Y, Zhang Y, Chen X
Neural regeneration research 2024 May;19(5):1105-1111
Neural regeneration research 2024 May;19(5):1105-1111
Protective effect of alirocumab, a PCSK9 inhibitor, on the sciatic nerve of rats with diabetic peripheral neuropathy.
Cui N, Feng Y, Wang M, Lu X, Huang Y, Chen Y, Shi X
Endocrine journal 2024 Mar 28;71(3):233-244
Endocrine journal 2024 Mar 28;71(3):233-244
Enhancing axonal myelination: Clemastine attenuates cognitive impairment in a rat model of diffuse traumatic brain injury.
Huang Z, Feng Y, Zhang Y, Ma X, Zong X, Jordan JD, Zhang Q
Translational research : the journal of laboratory and clinical medicine 2024 Jun;268:40-50
Translational research : the journal of laboratory and clinical medicine 2024 Jun;268:40-50
Exogenous NADPH could mitigate pyroptosis-induced brain injury in fetal mice exposed to gestational intermittent hypoxia.
Wei J, Zheng W, Teng C, An X, Li L, Zhong P, Peng C, Zhuge S, Akoto Ampadu J, Yu C, Cai X
International immunopharmacology 2024 Jun 30;135:112311
International immunopharmacology 2024 Jun 30;135:112311
Selective bioaccumulation of polystyrene nanoplastics in fetal rat brain and damage to myelin development.
Zhang Y, Tian L, Chen J, Liu X, Li K, Liu H, Lai W, Shi Y, Lin B, Xi Z
Ecotoxicology and environmental safety 2024 Jun 15;278:116393
Ecotoxicology and environmental safety 2024 Jun 15;278:116393
Circadian misalignment impairs oligodendrocyte myelination via Bmal1 overexpression leading to anxiety and depression-like behaviors.
Zuo Y, Hou Y, Wang Y, Yuan L, Cheng L, Zhang T
Journal of pineal research 2024 Jan;76(1):e12935
Journal of pineal research 2024 Jan;76(1):e12935
Matrine Mediated Immune Protection in MS by Regulating Gut Microbiota and Production of SCFAs.
Dou M, Chu Y, Zhou X, Wang M, Li X, Ma R, Fan Z, Zhao X, Wang W, Li S, Lv Y, Zhu L
Molecular neurobiology 2024 Jan;61(1):74-90
Molecular neurobiology 2024 Jan;61(1):74-90
Clemastine-induced enhancement of hippocampal myelination alleviates memory impairment in mice with chronic pain.
Zhu TT, Wang H, Liu PM, Gu HW, Pan WT, Zhao MM, Hashimoto K, Yang JJ
Neurobiology of disease 2024 Jan;190:106375
Neurobiology of disease 2024 Jan;190:106375
A High MCT-Based Ketogenic Diet Suppresses Th1 and Th17 Responses to Ameliorate Experimental Autoimmune Encephalomyelitis in Mice by Inhibiting GSDMD and JAK2-STAT3/4 Pathways.
Zhang Q, Sun W, Wang Q, Zheng X, Zhang R, Zhang N
Molecular nutrition & food research 2024 Feb;68(3):e2300602
Molecular nutrition & food research 2024 Feb;68(3):e2300602
Targeting Ferroptosis Promotes Functional Recovery by Mitigating White Matter Injury Following Acute Carbon Monoxide Poisoning.
Wang S, Xiong B, Tian Y, Hu Q, Jiang X, Zhang J, Chen L, Wang R, Li M, Zhou X, Zhang T, Ge H, Yu A
Molecular neurobiology 2024 Feb;61(2):1157-1174
Molecular neurobiology 2024 Feb;61(2):1157-1174
Sevoflurane causes cognitive impairment by inducing iron deficiency and inhibiting the proliferation of neural precursor cells in infant mice.
Zuo Y, Xie J, Zhang X, Thirupathi A, Liu X, Zhang D, Zhang J, Shi Z
CNS neuroscience & therapeutics 2024 Feb;30(2):e14612
CNS neuroscience & therapeutics 2024 Feb;30(2):e14612
Combining PLGA microspheres loaded with Liver X receptor agonist GW3965 with a chitosan nerve conduit can promote the healing and regeneration of the wounded sciatic nerve.
Zhong Y, Li S, Chen Y, Tang Y, Xiao X, Nie T
Journal of biomedical materials research. Part B, Applied biomaterials 2024 Feb;112(2):e35378
Journal of biomedical materials research. Part B, Applied biomaterials 2024 Feb;112(2):e35378
Complanatuside A improves functional recovery after spinal cord injury through inhibiting JNK signaling-mediated microglial activation.
Xu Y, Geng Z, Sun Y, Zhu G, Xiao L, Wang Z, Li B, Liu X, Shi J, Song X, Hu J, Qi Q
European journal of pharmacology 2024 Feb 15;965:176287
European journal of pharmacology 2024 Feb 15;965:176287
Antidepressant effect of teriflunomide via oligodendrocyte protection in a mouse model.
Luo S, Wu F, Fang Q, Hu Y, Zhang H, Yuan S, Yang C, Shi Y, Luo Y
Heliyon 2024 Apr 30;10(8):e29481
Heliyon 2024 Apr 30;10(8):e29481
Sildenafil Enhances the Therapeutic Effect of Islet Transplantation for Diabetic Peripheral Neuropathy via mTOR/S6K1 Pathway.
Zhu X, Xie S, Chen J, Lu Q, Wang X, Duan F, Xu S, Zhang Y, Huang H, Wang Y, Wang H, Chen B, Huang H
International journal of endocrinology 2023;2023:8199029
International journal of endocrinology 2023;2023:8199029
The neuroprotective effect of dl-3-n-butylphthalide on the brain with experimental intracerebral hemorrhage.
Fang M, Hou H, Feng B, Zhang T, Zhu X, Liu Z
European journal of pharmacology 2023 Nov 15;959:176105
European journal of pharmacology 2023 Nov 15;959:176105
Engineered extracellular vesicles for delivery of siRNA promoting targeted repair of traumatic spinal cord injury.
Rong Y, Wang Z, Tang P, Wang J, Ji C, Chang J, Zhu Y, Ye W, Bai J, Liu W, Yin G, Yu L, Zhou X, Cai W
Bioactive materials 2023 May;23:328-342
Bioactive materials 2023 May;23:328-342
Bone marrow mesenchymal stem cells and exercise restore motor function following spinal cord injury by activating PI3K/AKT/mTOR pathway.
Sun X, Huang LY, Pan HX, Li LJ, Wang L, Pei GQ, Wang Y, Zhang Q, Cheng HX, He CQ, Wei Q
Neural regeneration research 2023 May;18(5):1067-1075
Neural regeneration research 2023 May;18(5):1067-1075
Brain-Derived Estrogen Regulates Neurogenesis, Learning and Memory with Aging in Female Rats.
Huang Y, Sun W, Gao F, Ma H, Yuan T, Liu Z, Liu H, Hu J, Bai J, Zhang X, Wang R
Biology 2023 May 23;12(6)
Biology 2023 May 23;12(6)
Mesenchymal stem cells transplantation combined with IronQ attenuates ICH-induced inflammation response via Mincle/syk signaling pathway.
Yang G, Kantapan J, Mazhar M, Bai X, Zou Y, Wang H, Huang B, Yang S, Dechsupa N, Wang L
Stem cell research & therapy 2023 May 15;14(1):131
Stem cell research & therapy 2023 May 15;14(1):131
Baicalin facilitates remyelination and suppresses neuroinflammation in rats with chronic cerebral hypoperfusion by activating Wnt/β-catenin and inhibiting NF-κB signaling.
Xiao Y, Guan T, Yang X, Xu J, Zhang J, Qi Q, Teng Z, Dong Y, Gao Y, Li M, Meng N, Lv P
Behavioural brain research 2023 Mar 28;442:114301
Behavioural brain research 2023 Mar 28;442:114301
Neuroprotective effect of aloe emodin against Huntington's disease-like symptoms in R6/1 transgenic mice.
Yan N, Wang S, Gao H, Chen J, Cao J, Wei P, Li X, Yu Y, Wang Y, Niu Y, Wang Y, Liu S, Jin G
Food & function 2023 Jun 6;14(11):5205-5216
Food & function 2023 Jun 6;14(11):5205-5216
Macrophage lineage cells-derived migrasomes activate complement-dependent blood-brain barrier damage in cerebral amyloid angiopathy mouse model.
Hu M, Li T, Ma X, Liu S, Li C, Huang Z, Lin Y, Wu R, Wang S, Lu D, Lu T, Men X, Shen S, Huang H, Liu Y, Song K, Jian B, Jiang Y, Qiu W, Liu Q, Lu Z, Cai W
Nature communications 2023 Jul 4;14(1):3945
Nature communications 2023 Jul 4;14(1):3945
Sigma-1 Receptor Activation Improves Oligodendrogenesis and Promotes White-Matter Integrity after Stroke in Mice with Diabetic Mellitus.
Song W, Yao Y, Zhang H, Hao X, Zhou L, Song Z, Wei T, Chi T, Liu P, Ji X, Zou L
Molecules (Basel, Switzerland) 2023 Jan 2;28(1)
Molecules (Basel, Switzerland) 2023 Jan 2;28(1)
Spatial and temporal alterations of developing oligodendrocytes induced by repeated sevoflurane exposure in neonatal mice.
Zhang Z, Liu H, Jia S, Zhao J, Wang J, Liu Y, Zhou F, Li Q, Li Z, Dong H, Zeng Y, Zhang R, Zhong H
Biochemical and biophysical research communications 2023 Jan 15;640:12-20
Biochemical and biophysical research communications 2023 Jan 15;640:12-20
Remyelination in neuromyelitis optica spectrum disorder is promoted by edaravone through mTORC1 signaling activation.
Luo W, Xu H, Xu L, Jiang W, Chen C, Chang Y, Liu C, Tian Z, Qiu X, Xie C, Li X, Chen H, Lai S, Wu L, Cui Y, Tang C, Qiu W
Glia 2023 Feb;71(2):284-304
Glia 2023 Feb;71(2):284-304
Jatrorrhizine ameliorates Schwann cell myelination via inhibiting HDAC3 ability to recruit Atxn2l for regulating the NRG1-ErbB2-PI3K-AKT pathway in diabetic peripheral neuropathy mice.
Gong X, Gui Z, Ye X, Li X
Phytotherapy research : PTR 2023 Feb;37(2):645-657
Phytotherapy research : PTR 2023 Feb;37(2):645-657
Erythrocyte Plasma Membrane Lipid Composition Mirrors That of Neurons and Glial Cells in Murine Experimental In Vitro and In Vivo Inflammation.
Stanzani A, Sansone A, Brenna C, Baldassarro VA, Alastra G, Lorenzini L, Chatgilialoglu C, Laface I, Ferreri C, Neri LM, Calzà L
Cells 2023 Feb 9;12(4)
Cells 2023 Feb 9;12(4)
Supramolecular Hydrogel Microspheres of Platelet-Derived Growth Factor Mimetic Peptide Promote Recovery from Spinal Cord Injury.
Wu W, Jia S, Xu H, Gao Z, Wang Z, Lu B, Ai Y, Liu Y, Liu R, Yang T, Luo R, Hu C, Kong L, Huang D, Yan L, Yang Z, Zhu L, Hao D
ACS nano 2023 Feb 28;17(4):3818-3837
ACS nano 2023 Feb 28;17(4):3818-3837
Insulin-like Growth Factor-1 Prevents Hypoxia/Reoxygenation-Induced White Matter Injury in Sickle Cell Mice.
Hazra R, Hubert H, Little-Ihrig L, Ghosh S, Ofori-Acquah S, Hu X, Novelli EM
Biomedicines 2023 Feb 24;11(3)
Biomedicines 2023 Feb 24;11(3)
Rapamycin Exerts an Antidepressant Effect and Enhances Myelination in the Prefrontal Cortex of Chronic Restraint Stress Mice.
Zhang J, Li W, Yue Q, Liu L, Hou ST, Ju J
Neuroscience 2023 Dec 15;535:99-107
Neuroscience 2023 Dec 15;535:99-107
Neuron-Derived Exosomes Promote the Recovery of Spinal Cord Injury by Modulating Nerve Cells in the Cellular Microenvironment of the Lesion Area.
Xu Y, Zhu ZH, Xu X, Sun HT, Zheng HM, Zhang JL, Wang HH, Fang JW, Liu YZ, Huang LL, Song ZW, Liu JB
Molecular neurobiology 2023 Aug;60(8):4502-4516
Molecular neurobiology 2023 Aug;60(8):4502-4516
Ropivacaine microsphere-loaded electroconductive nerve dressings for long-acting analgesia and functional recovery following diabetic peripheral nerve injury.
Liang F, Yang Y, Chen Y, Xie J, Liu S, Tan Z, Tian L, Yu Z, Shi Z, Xie P, Ding H, Yang Q
Materials today. Bio 2023 Aug;21:100712
Materials today. Bio 2023 Aug;21:100712
Nattokinase Promotes Post-stroke Neurogenesis and Cognition Recovery via Increasing Circulating Irisin.
Wu H, Zhang Q, Xu P, Chen J, Duan L, Xu F, Zhang F
Journal of agricultural and food chemistry 2023 Aug 2;71(30):11418-11428
Journal of agricultural and food chemistry 2023 Aug 2;71(30):11418-11428
Apolipoprotein E Polymorphism Impacts White Matter Injury Through Microglial Phagocytosis After Experimental Subarachnoid Hemorrhage.
Li C, Lu P, Zhang L, He Y, Zhang L, Yang L, Zhang F, Kong X, Tao Q, Zhou J, Wu J, Peng T, Xie B, Jiang Y, Peng J
Neuroscience 2023 Aug 1;524:220-232
Neuroscience 2023 Aug 1;524:220-232
Lipid-accumulated reactive astrocytes promote disease progression in epilepsy.
Chen ZP, Wang S, Zhao X, Fang W, Wang Z, Ye H, Wang MJ, Ke L, Huang T, Lv P, Jiang X, Zhang Q, Li L, Xie ST, Zhu JN, Hang C, Chen D, Liu X, Yan C
Nature neuroscience 2023 Apr;26(4):542-554
Nature neuroscience 2023 Apr;26(4):542-554
FOXP3+ macrophage represses acute ischemic stroke-induced neural inflammation.
Cai W, Hu M, Li C, Wu R, Lu D, Xie C, Zhang W, Li T, Shen S, Huang H, Qiu W, Liu Q, Lu Y, Lu Z
Autophagy 2023 Apr;19(4):1144-1163
Autophagy 2023 Apr;19(4):1144-1163
Catalpol Regulates Oligodendrocyte Regeneration and Remyelination by Activating the GEF-Cdc42/Rac1 Signaling Pathway in EAE Mice.
Wu M, Kang Q, Kang Y, Tong Y, Yang T, Fan Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7074157
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7074157
ADSCs Combined with Melatonin Promote Peripheral Nerve Regeneration through Autophagy.
Zhang Z, Zhang M, Zhang Z, Sun Y, Wang J, Chang C, Zhu X, Li M, Liu Y
International journal of endocrinology 2022;2022:5861553
International journal of endocrinology 2022;2022:5861553
Behavioral and Molecular Consequences of Chronic Sleep Restriction During Development in Fragile X Mice.
Saré RM, Song A, Levine M, Lemons A, Loutaev I, Sheeler C, Hildreth C, Mfon A, Smith CB
Frontiers in neuroscience 2022;16:834890
Frontiers in neuroscience 2022;16:834890
Effect of β-hydroxybutyrate on behavioral alterations, molecular and morphological changes in CNS of multiple sclerosis mouse model.
Sun W, Wen M, Liu M, Wang Q, Liu Q, Li L, Siebert HC, Loers G, Zhang R, Zhang N
Frontiers in aging neuroscience 2022;14:1075161
Frontiers in aging neuroscience 2022;14:1075161
Novel recombinant protein flagellin A N/C attenuates experimental autoimmune encephalomyelitis by suppressing the ROS/NF-κB/NLRP3 signaling pathway.
Li L, Deng S, Liu M, Yang M, Li J, Liu T, Zhang T, Zhao Y, He M, Wu D, Xu Y
Frontiers in pharmacology 2022;13:956402
Frontiers in pharmacology 2022;13:956402
Delivery of Basic Fibroblast Growth Factor Through an In Situ Forming Smart Hydrogel Activates Autophagy in Schwann Cells and Improves Facial Nerves Generation via the PAK-1 Signaling Pathway.
Hu B, Zhang H, Xu M, Li L, Wu M, Zhang S, Liu X, Xia W, Xu K, Xiao J, Zhang H, Ni L
Frontiers in pharmacology 2022;13:778680
Frontiers in pharmacology 2022;13:778680
Enhanced effect of combining bone marrow mesenchymal stem cells (BMMSCs) and pulsed electromagnetic fields (PEMF) to promote recovery after spinal cord injury in mice.
Huang L, Sun X, Wang L, Pei G, Wang Y, Zhang Q, Liang Z, Wang D, Fu C, He C, Wei Q
MedComm 2022 Sep;3(3):e160
MedComm 2022 Sep;3(3):e160
HDAC3 Inhibitor RGFP966 Ameliorated Neuroinflammation in the Cuprizone-Induced Demyelinating Mouse Model and LPS-Stimulated BV2 Cells by Downregulating the P2X7R/STAT3/NF-κB65/NLRP3 Activation.
Sun W, Zhang N, Liu B, Yang J, Loers G, Siebert HC, Wen M, Zheng X, Wang Z, Han J, Zhang R
ACS chemical neuroscience 2022 Sep 7;13(17):2579-2598
ACS chemical neuroscience 2022 Sep 7;13(17):2579-2598
Stemazole Promotes Oligodendrocyte Precursor Cell Survival In Vitro and Remyelination In Vivo.
Zhu Y, Chen M, Zhang Y, Han M
International journal of molecular sciences 2022 Sep 15;23(18)
International journal of molecular sciences 2022 Sep 15;23(18)
Ginsenoside Rg1 promotes remyelination and functional recovery in demyelinating disease by enhancing oligodendrocyte precursor cells-mediated myelin repair.
Liu L, Du X, Yang Q, Li M, Ran Q, Liu Q, Yang L, Sun L, Guo Y, Li Y, Chen Y, Zhu X, Li Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Nov;106:154309
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Nov;106:154309
The divergent effects of astrocyte ceruloplasmin on learning and memory function in young and old mice.
Li ZD, Li H, Kang S, Cui YG, Zheng H, Wang P, Han K, Yu P, Chang YZ
Cell death & disease 2022 Nov 28;13(11):1006
Cell death & disease 2022 Nov 28;13(11):1006
Neutrophil Nanovesicle Protects against Experimental Autoimmune Encephalomyelitis through Enhancing Myelin Clearance by Microglia.
Shen S, Cheng X, Zhou L, Zhao Y, Wang H, Zhang J, Sun X, Wang Y, Shu Y, Xu Y, Tao Y, Li M, Lu Z, Cai W, Nie G, Qiu W
ACS nano 2022 Nov 22;16(11):18886-18897
ACS nano 2022 Nov 22;16(11):18886-18897
Expression and immunogenicity of nsp10 protein of porcine epidemic diarrhea virus.
Zhu L, Liu S, Zhuo Z, Lin Y, Zhang Y, Wang X, Kong L, Wang T
Research in veterinary science 2022 May;144:34-43
Research in veterinary science 2022 May;144:34-43
E3 ubiquitin ligase Triad1 promotes neuronal apoptosis by regulating the p53-caspase3 pathway after spinal cord injury.
Wu C, Zhang H, Hong H, Chen C, Chen J, Zhang J, Xue P, Jiang J, Cui Z
Somatosensory & motor research 2022 Mar;39(1):21-28
Somatosensory & motor research 2022 Mar;39(1):21-28
SPIONs mediated magnetic actuation promotes nerve regeneration by inducing and maintaining repair-supportive phenotypes in Schwann cells.
Liu T, Wang Y, Lu L, Liu Y
Journal of nanobiotechnology 2022 Mar 27;20(1):159
Journal of nanobiotechnology 2022 Mar 27;20(1):159
Development of a Chemical Cocktail That Rescues Mouse Brain Demyelination in a Cuprizone-Induced Model.
Lai PL, Ng CH, Wu CH, Lai CY, Schuyler SC, Wang V, Lin H, Lee YC, Chuang MH, Yang CH, Chen WJ, Huang HC, Lu J
Cells 2022 Mar 24;11(7)
Cells 2022 Mar 24;11(7)
Sensory neurons have an axon initial segment that initiates spontaneous activity in neuropathic pain.
Nascimento AI, Da Silva TF, Fernandes EC, Luz LL, Mar FM, Safronov BV, Sousa MM
Brain : a journal of neurology 2022 Jun 3;145(5):1632-1640
Brain : a journal of neurology 2022 Jun 3;145(5):1632-1640
C1q inhibits differentiation of oligodendrocyte progenitor cells via Wnt/β-catenin signaling activation in a cuprizone-induced mouse model of multiple sclerosis.
Gao Z, Zhang C, Feng Z, Liu Z, Yang Y, Yang K, Chen L, Yao R
Experimental neurology 2022 Feb;348:113947
Experimental neurology 2022 Feb;348:113947
Rewired glycosylation activity promotes scarless regeneration and functional recovery in spiny mice after complete spinal cord transection.
Nogueira-Rodrigues J, Leite SC, Pinto-Costa R, Sousa SC, Luz LL, Sintra MA, Oliveira R, Monteiro AC, Pinheiro GG, Vitorino M, Silva JA, Simão S, Fernandes VE, Provazník J, Benes V, Cruz CD, Safronov BV, Magalhães A, Reis CA, Vieira J, Vieira CP, Tiscórnia G, Araújo IM, Sousa MM
Developmental cell 2022 Feb 28;57(4):440-450.e7
Developmental cell 2022 Feb 28;57(4):440-450.e7
Preparation, Characterization, Evaluation of Neuroprotective Effect, and Related Mechanisms of Phosphatidylserine Emulsion in 5- and 12-Week Old Mice.
Liu B, Zhang N, Yang J, Sun W, Zhang R, Zheng X, Wang Z, Siebert HC, Han J
Journal of agricultural and food chemistry 2022 Feb 16;70(6):1852-1864
Journal of agricultural and food chemistry 2022 Feb 16;70(6):1852-1864
Dose optimization of intrathecal administration of human umbilical cord mesenchymal stem cells for the treatment of subacute incomplete spinal cord injury.
Cao TT, Chen H, Pang M, Xu SS, Wen HQ, Liu B, Rong LM, Li MM
Neural regeneration research 2022 Aug;17(8):1785-1794
Neural regeneration research 2022 Aug;17(8):1785-1794
An in vivo implementation of the MEX MRI for myelin fraction of mice brain.
Wilczynski E, Sasson E, Eliav U, Navon G, Nevo U
Magma (New York, N.Y.) 2022 Apr;35(2):267-276
Magma (New York, N.Y.) 2022 Apr;35(2):267-276
Multifunctional biomimetic hydrogel based on graphene nanoparticles and sodium alginate for peripheral nerve injury therapy.
Jin Y, Zhang W, Zhang Y, Yang Y, Fang Z, Song J, Qian Y, Yuan WE
Biomaterials advances 2022 Apr;135:212727
Biomaterials advances 2022 Apr;135:212727
The microbiota-gut-brain axis participates in chronic cerebral hypoperfusion by disrupting the metabolism of short-chain fatty acids.
Xiao W, Su J, Gao X, Yang H, Weng R, Ni W, Gu Y
Microbiome 2022 Apr 17;10(1):62
Microbiome 2022 Apr 17;10(1):62
Photobiomodulation Therapy Attenuates Anxious-Depressive-Like Behavior in the TgF344 Rat Model.
Yang L, Wu C, Tucker L, Dong Y, Li Y, Xu P, Zhang Q
Journal of Alzheimer's disease : JAD 2021;83(4):1415-1429
Journal of Alzheimer's disease : JAD 2021;83(4):1415-1429
Connexin43 promotes angiogenesis through activating the HIF-1α/VEGF signaling pathway under chronic cerebral hypoperfusion.
Yu W, Jin H, Sun W, Nan D, Deng J, Jia J, Yu Z, Huang Y
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2021 Oct;41(10):2656-2675
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2021 Oct;41(10):2656-2675
Transfer of α-synuclein from neurons to oligodendrocytes triggers myelin sheath destruction in methamphetamine administration mice.
Ding J, Huang J, Xia B, Hu S, Fan H, Dai J, Li Z, Wang J, Le C, Qiu P, Wang Y
Toxicology letters 2021 Nov 1;352:34-45
Toxicology letters 2021 Nov 1;352:34-45
Maternal high sugar and fat diet benefits offspring brain function via targeting on the gut-brain axis.
Wang D, Zhang H, Zeng M, Tang X, Zhu X, Guo Y, Qi L, Xie Y, Zhang M, Chen D
Aging 2021 Mar 26;13(7):10240-10274
Aging 2021 Mar 26;13(7):10240-10274
A five-m6A regulatory gene signature is a prognostic biomarker in lung adenocarcinoma patients.
Wu X, Sheng H, Wang L, Xia P, Wang Y, Yu L, Lv W, Hu J
Aging 2021 Mar 26;13(7):10034-10057
Aging 2021 Mar 26;13(7):10034-10057
A Novel Rat Model with Long Range Optic Nerve Injury to Study Retinal Ganglion Cells Endogenous Regeneration.
Zhang S, Liu B, Zhu H, Jin H, Gong Z, Qiu H, Xu M, Chen M, Nan K, Wu W
Neuroscience 2021 Jun 15;465:71-84
Neuroscience 2021 Jun 15;465:71-84
Evaluation of cytokines and structural proteins to analyze the pathology of febrile central nervous system disease.
Ikeda T, Tani N, Watanabe M, Hirokawa T, Ikeda K, Morioka F, Ishikawa T
Legal medicine (Tokyo, Japan) 2021 Jul;51:101864
Legal medicine (Tokyo, Japan) 2021 Jul;51:101864
Intranasal administration of DHED protects against exhaustive exercise-induced brain injury in rats.
Peng G, Zheng H, Wu C, Wu C, Ma X, Xiong J, Hou J, Zhang L, Yang L, Pan H
Brain research 2021 Dec 1;1772:147665
Brain research 2021 Dec 1;1772:147665
Caffeic Acid Phenethyl Ester Protects against Experimental Autoimmune Encephalomyelitis by Regulating T Cell Activities.
Zhou Y, Wang J, Chang Y, Li R, Sun X, Peng L, Zheng W, Qiu W
Oxidative medicine and cellular longevity 2020;2020:7274342
Oxidative medicine and cellular longevity 2020;2020:7274342
Acupuncture Improves White Matter Perfusion and Integrity in Rat Model of Vascular Dementia: An MRI-Based Imaging Study.
Ma SM, Wang L, Su XT, Yang NN, Huang J, Lin LL, Shao JK, Yang JW, Liu CZ
Frontiers in aging neuroscience 2020;12:582904
Frontiers in aging neuroscience 2020;12:582904
Bixin Attenuates Experimental Autoimmune Encephalomyelitis by Suppressing TXNIP/NLRP3 Inflammasome Activity and Activating NRF2 Signaling.
Yu Y, Wu DM, Li J, Deng SH, Liu T, Zhang T, He M, Zhao YY, Xu Y
Frontiers in immunology 2020;11:593368
Frontiers in immunology 2020;11:593368
The combined treatment of NAD(+) and atorvastatin ameliorates the development of experimental autoimmune encephalomyelitis in C57BL/6 mice.
Sun H, Wang J, Guo L, Wang Y, Zhang J, Wang J, Quan M, Li B
Journal of neuroimmunology 2020 Oct 24;350:577429
Journal of neuroimmunology 2020 Oct 24;350:577429
Subarachnoid transplantation of human umbilical cord mesenchymal stem cell in rodent model with subacute incomplete spinal cord injury: Preclinical safety and efficacy study.
Yang Y, Cao TT, Tian ZM, Gao H, Wen HQ, Pang M, He WJ, Wang NX, Chen YY, Wang Y, Li H, Lin JW, Kang Z, Li MM, Liu B, Rong LM
Experimental cell research 2020 Oct 15;395(2):112184
Experimental cell research 2020 Oct 15;395(2):112184
Deficiency of microglial Hv1 channel is associated with activation of autophagic pathway and ROS production in LPC-induced demyelination mouse model.
Chen M, Yang LL, Hu ZW, Qin C, Zhou LQ, Duan YL, Bosco DB, Wu LJ, Zhan KB, Xu SB, Tian DS
Journal of neuroinflammation 2020 Nov 6;17(1):333
Journal of neuroinflammation 2020 Nov 6;17(1):333
Sevoflurane anesthesia during pregnancy in mice induces cognitive impairment in the offspring by causing iron deficiency and inhibiting myelinogenesis.
Zuo Y, Li B, Xie J, Ma Z, Thirupathi A, Yu P, Gao G, Zhou J, Zhou C, Xu H, Chang Y, Shi Z
Neurochemistry international 2020 May;135:104693
Neurochemistry international 2020 May;135:104693
Arsenic trioxide ameliorates experimental autoimmune encephalomyelitis in C57BL/6 mice by inducing CD4(+) T cell apoptosis.
An K, Xue MJ, Zhong JY, Yu SN, Lan TS, Qi ZQ, Xia JJ
Journal of neuroinflammation 2020 May 6;17(1):147
Journal of neuroinflammation 2020 May 6;17(1):147
Triclosan induces zebrafish neurotoxicity by abnormal expression of miR-219 targeting oligodendrocyte differentiation of central nervous system.
Ling Y, Sun L, Wang D, Jiang J, Sun W, Ai W, Wang X, Wang H
Archives of toxicology 2020 Mar;94(3):857-871
Archives of toxicology 2020 Mar;94(3):857-871
Amelioration of clinical course and demyelination in the cuprizone mouse model in relation to ketogenic diet.
Zhang N, Liu C, Zhang R, Jin L, Yin X, Zheng X, Siebert HC, Li Y, Wang Z, Loers G, Petridis AK
Food & function 2020 Jun 24;11(6):5647-5663
Food & function 2020 Jun 24;11(6):5647-5663
Chronic Sleep Restriction in Developing Male Mice Results in Long Lasting Behavior Impairments.
Saré RM, Song A, Levine M, Lemons A, Loutaev I, Sheeler C, Hildreth C, Mfon A, Cooke S, Smith CB
Frontiers in behavioral neuroscience 2019;13:90
Frontiers in behavioral neuroscience 2019;13:90
Myelin Oligodendrocyte Glycoprotein-IgG Contributes to Oligodendrocytopathy in the Presence of Complement, Distinct from Astrocytopathy Induced by AQP4-IgG.
Fang L, Kang X, Wang Z, Wang S, Wang J, Zhou Y, Chen C, Sun X, Yan Y, Kermode AG, Peng L, Qiu W
Neuroscience bulletin 2019 Oct;35(5):853-866
Neuroscience bulletin 2019 Oct;35(5):853-866
Integral membrane protein 2A inhibits cell growth in human breast cancer via enhancing autophagy induction.
Zhou C, Wang M, Yang J, Xiong H, Wang Y, Tang J
Cell communication and signaling : CCS 2019 Aug 22;17(1):105
Cell communication and signaling : CCS 2019 Aug 22;17(1):105
Mesenchymal Stem Cell-Derived Exosomes Reduce A1 Astrocytes via Downregulation of Phosphorylated NFκB P65 Subunit in Spinal Cord Injury.
Wang L, Pei S, Han L, Guo B, Li Y, Duan R, Yao Y, Xue B, Chen X, Jia Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(4):1535-1559
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(4):1535-1559
Sigma-1 receptor activation alleviates blood-brain barrier dysfunction in vascular dementia mice.
Liu DY, Chi TY, Ji XF, Liu P, Qi XX, Zhu L, Wang ZQ, Li L, Chen L, Zou LB
Experimental neurology 2018 Oct;308:90-99
Experimental neurology 2018 Oct;308:90-99
Structural and visual functional deficits in a rat model of neuromyelitis optica spectrum disorders related optic neuritis.
Zhang Y, Bao Y, Qiu W, Peng L, Fang L, Xu Y, Yang H
Experimental eye research 2018 Oct;175:124-132
Experimental eye research 2018 Oct;175:124-132
ST8SIA2 promotes oligodendrocyte differentiation and the integrity of myelin and axons.
Szewczyk LM, Brozko N, Nagalski A, Röckle I, Werneburg S, Hildebrandt H, Wisniewska MB, Kuznicki J
Glia 2017 Jan;65(1):34-49
Glia 2017 Jan;65(1):34-49
Protective Effect of 17β-Estradiol Upon Hippocampal Spine Density and Cognitive Function in an Animal Model of Vascular Dementia.
Zhu Y, Zhang Q, Zhang W, Li N, Dai Y, Tu J, Yang F, Brann DW, Wang R
Scientific reports 2017 Feb 16;7:42660
Scientific reports 2017 Feb 16;7:42660
Treatment with NAD(+) inhibited experimental autoimmune encephalomyelitis by activating AMPK/SIRT1 signaling pathway and modulating Th1/Th17 immune responses in mice.
Wang J, Zhao C, Kong P, Sun H, Sun Z, Bian G, Sun Y, Guo L
International immunopharmacology 2016 Oct;39:287-294
International immunopharmacology 2016 Oct;39:287-294
Methylene blue alleviates experimental autoimmune encephalomyelitis by modulating AMPK/SIRT1 signaling pathway and Th17/Treg immune response.
Wang J, Zhao C, Kong P, Bian G, Sun Z, Sun Y, Guo L, Li B
Journal of neuroimmunology 2016 Oct 15;299:45-52
Journal of neuroimmunology 2016 Oct 15;299:45-52
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Myelin basic protein antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Myelin basic protein. This antibody recognizes human,mouse,rat antigen. The Myelin basic protein antibody has been validated for the following applications: ELISA, WB analysis.