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- Product number
- 10458-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10458-1-AP, RRID:AB_2250289
- Product name
- Myelin basic protein antibody
- Antibody type
- Polyclonal
- Description
- Myelin basic protein antibody (Cat. #10458-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Biomimetic core-shell GelMA microspheres co-delivering ANXA1, NGF, and fibronectin enable phase-matched immunomodulation and neurorepair after spinal cord injury.
Ultrasound Activated Piezoelectric Dural Patches to Drive Endogenous Neural Stem Cell-Mediated Repair Traumatic Brain Injury.
Small extracellular vesicles derived from hair follicle neural crest stem cells enhance perineurial cell proliferation and migration via the TGF-β/SMAD/HAS2 pathway.
Clemastine ameliorates cognitive deficits in an experimental rat model of chronic cerebral hypoperfusion.
FUNDC1-dependent mitophagy determines axon regeneration capacity.
Bone marrow mesenchymal stem cells protect against cerebral amyloid angiopathy by enhancing neutrophil mitocytosis.
Fibrinogen contributes to myelin deficit and cognitive impairment in aged mice after anesthesia and surgery.
Salidroside ameliorates experimental autoimmune neuritis by dually modulating neuroinflammation and immune homeostasis via PI3K/AKT signaling.
Thermodynamic Delivery of Trehalose into Extracellular Vesicles for Enhanced Lyophilization.
The effect of 807-nm light-emitting diode photobiomodulation on peripheral nerve injury.
Rewiring brain structural and functional disconnection with acupuncture in rat model of vascular cognitive impairment and dementia.
Puerarin Attenuates White Matter Injury and Blood-Brain Barrier Disruption After Intracerebral Hemorrhagic Stroke via cGAS-STING Axis.
Activation status of astrocytes drives the MS/NMOSD therapeutic paradox: Insights from IFNAR1 signaling.
EGCG-loaded nanoparticles attenuate post-SAH white matter injury by targeting HO-1/S100A10 to suppress oxidative stress-induced reactive astrocytes.
Engineered exosomes mediated siNox4 delivery loaded polyzwitterionic hydrogel with electrophysiologic conductivity for synergistic treatment of spinal cord injury via suppressing neuronal ferroptosis.
Tianwang Buxin Pill improves cognitive function in APP/PS1 mice by reducing neuronal damage and regulating synaptic plasticity.
Resveratrol Attenuates Neuroinflammation and Myelination Deficits in Repeated Sevoflurane-Exposed Neonatal Mice.
Self-cleavage-dependent and -independent functions of Adgrg1/Gpr56 in mice.
IMR-1 ameliorates perinatal LPS-induced brain injury by promoting the conversion of glial cells into neurons.
KDM2B-PP1 Promotes Remyelination and Functional Recovery After Facial Nerve Injury.
Repetitive Trans-spinal Magnetic Stimulation Suppresses Microglia to Engulf Synapse and Promotes Nerve Repairment via cGAS-STING Signaling Pathway after Spinal Cord Injury.
Validation of a data-driven multicomponent T2 analysis for quantifying myelin content in the cuprizone mouse model of multiple sclerosis.
TRIM37-mediated stabilization of PEX5 via monoubiquitination attenuates oxidative stress and demyelination in multiple sclerosis insights from EAE and LPC-induced experimental models.
Injectable ion-coordinated double-network conductive hydrogel for spinal cord injury repair.
Targeting the miR-96-5p/Cathepsin B Pathway to Alleviate Neuron-Derived Neuroinflammation in Alzheimer's Disease.
The role of astrocyte-derived extracellular vesicles in cellular microenvironment remodeling after spinal cord injury: A study based on quantitative proteomics analysis.
Furongtongmai capsule alleviates neuroinflammation by downregulating the TLR4/MyD88/JNK pathway to promote the recovery of peripheral nerve compression.
A Myelin Debris Cleaner for Spinal Cord Injury Recovery: Polycaprolactone / Cell Membrane Assembled Scaffolds.
Oligodendrocyte-specific knockout of FPN1 affects CNS myelination defects and depression-like behavior in mice.
Neonatal sevoflurane exposure disrupted fatty acids metabolism, leading to hypomyelination and neurological impairments.
Poliumoside Alleviates Neuroinflammation and Oxidative Stress After Spinal Cord Injury by Activating the PI3K/AKT/mTOR Signaling Pathway.
Photobiomodulation as a therapeutic approach for attention-deficit/hyperactivity disorder in model rats.
Sex-dependent impairments in oligodendrocyte maturation and myelination in offspring mice exposed to preeclampsia.
Hepcidin/HIF-1α is involved in the endogenous recovery and ferroptosis after cerebral ischemia in mice.
Dual Mechanisms of Cognitive Function and Pathological Improvements by the Selective S1PR1/5 Modulator Siponimod in 3xTg-AD Mice.
Hydroxylation of HPPD facilitates its PUB11-mediated ubiquitination and degradation in response to oxidative stress in Arabidopsis.
Divergent MYB paralogs determine spatial distribution of linalool mediated by JA and DNA demethylation participating in aroma formation and cold tolerance of tea plants.
Pad2 deletion induces anxiety‑like behaviors and memory deficits in mice.
Single-cell and spatial transcriptomics analysis reveals that Pros1(+) oligodendrocytes are involved in endogenous neuroprotection after brainstem stroke.
SETD3-mediated histidine methylation of MCM7 regulates DNA replication by facilitating chromatin loading of MCM.
Inhibition of histamine receptor 3 alleviates sevoflurane-induced hypomyelination and neurobehavioral deficits.
Puerarin mitigates cognitive decline and white matter injury via CD36-Mediated microglial phagocytosis in chronic cerebral hypoperfusion.
Myelination Trajectory and Microglial Dynamics Following Repeated Sevoflurane Exposure in Developing Brain.
Activation of GPER1 alleviates white matter injury by promoting microglia M2 polarization through EGFR/Stat3 pathway in intracerebral hemorrhage mice.
Single-Cell RNA Sequencing and Spatial Transcriptomics Reveal a Novel Mechanism of Oligodendrocyte-Neuron Interaction in Cognitive Decline After High-Altitude Cerebral Edema.
Exercise-induced irisin ameliorates cognitive impairment following chronic cerebral hypoperfusion by suppressing neuroinflammation and hippocampal neuronal apoptosis.
Salidroside Exerts Neuroprotective Effects via Inhibiting Ferroptosis in Mice with Traumatic Brain Injury.
Pro-repair macrophages driven by CGRP rescue white matter integrity following intracerebral hemorrhage.
FOXP3(+) Macrophage-Derived Amphiregulin Promotes White Matter Repair of Experimental Autoimmune Encephalomyelitis.
Combined enriched environment and fluoxetine enhance myelin protein expression in the prefrontal cortex of a chronic unpredictable stress depression model.
Optimally Aligned Nerve Scaffolds with Sustained Astaxanthin Release Improve the Inflammatory Microenvironment through Mitophagy Activation.
The circadian clock module LgPRR7-LgFKF1 negatively regulates flowering time in Luculia gratissima, a woody ornamental plant.
Oligodendrocyte-Specific STAT5B Overexpression Ameliorates Myelin Impairment in Experimental Models of Parkinson's Disease.
The Upregulation of L1CAM by SVHRSP Mitigates Neuron Damage, Spontaneous Seizures, and Cognitive Dysfunction in a Kainic Acid-Induced Rat Model of Epilepsy.
Glutamate chemical exchange saturation transfer (GluCEST) MRI to evaluate the relationship between demyelination and glutamate content in depressed mice.
Lipidomics Analysis Reveals the Effects of Docosahexaenoic Acid from Different Sources on Prefrontal-Cortex Synaptic Plasticity.
TDP43 augments astrocyte inflammatory activity through mtDNA-cGAS-STING axis in NMOSD.
Rosiglitazone Promotes Oligodendrocyte Development and Myelin Formation of Repeated Neonatal Sevoflurane Exposure via PPARγ Signaling.
Intra-cisterna-magna bevacizumab injection (ICM-BI) reproduces pathological alterations of cerebral small vessel diseases.
Activation of PAR1 contributes to ferroptosis of Schwann cells and inhibits regeneration of myelin sheath after sciatic nerve crush injury in rats via Hippo-YAP/ACSL4 pathway.
Kaempferol attenuates experimental autoimmune neuritis through TNFR1/JNK/p38 signaling pathway inhibition.
Mesenchymal stem cells overexpressing neuropeptide S promote the recovery of rats with spinal cord injury by activating the PI3K/AKT/GSK3β signaling pathway.
Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons.
Neonatal sevoflurane exposures inhibits DHHC5-mediated palmitoylation of TfR1 in oligodendrocytes, leading to hypomyelination and neurological impairments.
Prospero-related homeobox protein 1 (Prox1) enhances myelin sheath regeneration in injured sciatic nerve.
Saracatinib Promotes Hippocampal Myelin Regeneration and Oligodendrocyte Precursor Cell Maturation by Inhibiting the NOTCH1 Signaling Pathway in Epileptic Mice.
Transcript Imbalance from TENM4 Exon Skipping: Effects on Epilepsy and Genetic Pleiotropy.
Ferroptosis is a novel pathogenic mechanism of FDXR-related disease via disruption of the NRF2 pathway.
The Neuroprotective Effect of 4-Octyl Itaconate on Acute Period of Experimental Autoimmune Neuritis.
Upregulating mTOR/S6 K Pathway by CASTOR1 Promotes Astrocyte Proliferation and Myelination in Gpam(-/-)-induced mouse model of cerebral palsy.
Diosgenin promoted OPCs differentiation via blocking GLUR2/GAPDH interaction in a pilocarpine rat model of epilepsy.
The foam cell-derived exosomes exacerbate ischemic white matter injury via transmitting metabolic defects to microglia.
Preventive and therapeutic effects of Tanshinone IIA on spinal cord injury without radiographic abnormality by regulating microglial phenotype polarization.
Electroacupuncture Protects Against Post-stroke Cognitive Impairment by Promoting an IL-33/ST2 Axis-Mediated Microglia M2 Polarization.
Dexmedetomidine Improves Long-term Neurological Outcomes by Promoting Oligodendrocyte Genesis and Myelination in Neonatal Rats Following Hypoxic-ischemic Brain Injury.
FGF21 Alleviates Hypoxic-Ischemic White Matter Injury in Neonatal Mice by Mediating Inflammation and Oxidative Stress Through PPAR-γ Signaling Pathway.
Double-target magnetic stimulation attenuates oligodendrocyte apoptosis and oxidative stress impairment after spinal cord injury via GAP43.
Ubiquitination-mediated upregulation of glycolytic enzyme MCT4 in promoting astrocyte reactivity during neuroinflammation.
The Influence of Pathological Extracellular Matrix on the Biological Properties of Stem Cells: Possible Hints for Cell Transplantation Therapies in Spinal Cord Injury.
VEGF secreted by human dental pulp stem cell promotes spinal cord injury repair by inhibiting microglial pyroptosis through the PI3K/AKT pathway.
Hypoxic Bone Mesenchymal Stem Cell-Derived Exosomes Direct Schwann Cells Proliferation, Migration, and Paracrine to Accelerate Facial Nerve Regeneration via circRNA_Nkd2/miR-214-3p/MED19 Axis.
Microglia aggravate white matter injury via C3/C3aR pathway after experimental subarachnoid hemorrhage.
The RhoB p.S73F mutation leads to cerebral palsy through dysregulation of lipid homeostasis.
Enhancing facial nerve regeneration with scaffold-free conduits engineered using dental pulp stem cells and their endogenous, aligned extracellular matrix.
Upregulated expression of ubiquitin ligase TRIM21 promotes PKM2 nuclear translocation and astrocyte activation in experimental autoimmune encephalomyelitis.
An injectable decellularized extracellular matrix hydrogel with cortical neuron-derived exosomes enhances tissue repair following traumatic spinal cord injury.
The Neuroprotective Mechanisms of PPAR-γ: Inhibition of Microglia-Mediated Neuroinflammation and Oxidative Stress in a Neonatal Mouse Model of Hypoxic-Ischemic White Matter Injury.
Construction of functional neural network tissue combining CBD-NT3-modified linear-ordered collagen scaffold and TrkC-modified iPSC-derived neural stem cells for spinal cord injury repair.
Nerve Guide Conduits Integrated with Fisetin-Loaded Chitosan Hydrogels for Reducing Oxidative Stress, Inflammation, and Nerve Regeneration.
Conditioned medium from human dental pulp stem cells treats spinal cord injury by inhibiting microglial pyroptosis.
Protective effect of alirocumab, a PCSK9 inhibitor, on the sciatic nerve of rats with diabetic peripheral neuropathy.
Enhancing axonal myelination: Clemastine attenuates cognitive impairment in a rat model of diffuse traumatic brain injury.
Exogenous NADPH could mitigate pyroptosis-induced brain injury in fetal mice exposed to gestational intermittent hypoxia.
Selective bioaccumulation of polystyrene nanoplastics in fetal rat brain and damage to myelin development.
Circadian misalignment impairs oligodendrocyte myelination via Bmal1 overexpression leading to anxiety and depression-like behaviors.
Matrine Mediated Immune Protection in MS by Regulating Gut Microbiota and Production of SCFAs.
Clemastine-induced enhancement of hippocampal myelination alleviates memory impairment in mice with chronic pain.
A High MCT-Based Ketogenic Diet Suppresses Th1 and Th17 Responses to Ameliorate Experimental Autoimmune Encephalomyelitis in Mice by Inhibiting GSDMD and JAK2-STAT3/4 Pathways.
Targeting Ferroptosis Promotes Functional Recovery by Mitigating White Matter Injury Following Acute Carbon Monoxide Poisoning.
Sevoflurane causes cognitive impairment by inducing iron deficiency and inhibiting the proliferation of neural precursor cells in infant mice.
Combining PLGA microspheres loaded with Liver X receptor agonist GW3965 with a chitosan nerve conduit can promote the healing and regeneration of the wounded sciatic nerve.
Complanatuside A improves functional recovery after spinal cord injury through inhibiting JNK signaling-mediated microglial activation.
Agomelatine promotes differentiation of oligodendrocyte precursor cells and preserves white matter integrity after cerebral ischemic stroke.
Temporal dynamics of neutrophil functions in multiple sclerosis.
DET1 modulates ATAF1-repressed thermosensory elongation through ubiquitination in Arabidopsis.
Methylene Blue Pretreatment Protects Against Repeated Neonatal Isoflurane Exposure-Induced Brain Injury and Memory Loss.
Digirseophene A promotes recovery in injured developing cerebellum via AMPK/AKT/GSK3β pathway-mediated neural stem cell proliferation.
Antidepressant effect of teriflunomide via oligodendrocyte protection in a mouse model.
Sildenafil Enhances the Therapeutic Effect of Islet Transplantation for Diabetic Peripheral Neuropathy via mTOR/S6K1 Pathway.
PKCε activator protects hippocampal microvascular disruption and memory defect in 3×Tg-Alzheimer's disease mice with cerebral microinfarcts.
The neuroprotective effect of dl-3-n-butylphthalide on the brain with experimental intracerebral hemorrhage.
Engineered extracellular vesicles for delivery of siRNA promoting targeted repair of traumatic spinal cord injury.
Bone marrow mesenchymal stem cells and exercise restore motor function following spinal cord injury by activating PI3K/AKT/mTOR pathway.
Brain-Derived Estrogen Regulates Neurogenesis, Learning and Memory with Aging in Female Rats.
Mesenchymal stem cells transplantation combined with IronQ attenuates ICH-induced inflammation response via Mincle/syk signaling pathway.
Baicalin facilitates remyelination and suppresses neuroinflammation in rats with chronic cerebral hypoperfusion by activating Wnt/β-catenin and inhibiting NF-κB signaling.
Neuroprotective effect of aloe emodin against Huntington's disease-like symptoms in R6/1 transgenic mice.
Macrophage lineage cells-derived migrasomes activate complement-dependent blood-brain barrier damage in cerebral amyloid angiopathy mouse model.
Sigma-1 Receptor Activation Improves Oligodendrogenesis and Promotes White-Matter Integrity after Stroke in Mice with Diabetic Mellitus.
Spatial and temporal alterations of developing oligodendrocytes induced by repeated sevoflurane exposure in neonatal mice.
Remyelination in neuromyelitis optica spectrum disorder is promoted by edaravone through mTORC1 signaling activation.
Jatrorrhizine ameliorates Schwann cell myelination via inhibiting HDAC3 ability to recruit Atxn2l for regulating the NRG1-ErbB2-PI3K-AKT pathway in diabetic peripheral neuropathy mice.
Erythrocyte Plasma Membrane Lipid Composition Mirrors That of Neurons and Glial Cells in Murine Experimental In Vitro and In Vivo Inflammation.
Supramolecular Hydrogel Microspheres of Platelet-Derived Growth Factor Mimetic Peptide Promote Recovery from Spinal Cord Injury.
Insulin-like Growth Factor-1 Prevents Hypoxia/Reoxygenation-Induced White Matter Injury in Sickle Cell Mice.
Rapamycin Exerts an Antidepressant Effect and Enhances Myelination in the Prefrontal Cortex of Chronic Restraint Stress Mice.
Neuron-Derived Exosomes Promote the Recovery of Spinal Cord Injury by Modulating Nerve Cells in the Cellular Microenvironment of the Lesion Area.
Ropivacaine microsphere-loaded electroconductive nerve dressings for long-acting analgesia and functional recovery following diabetic peripheral nerve injury.
Nattokinase Promotes Post-stroke Neurogenesis and Cognition Recovery via Increasing Circulating Irisin.
Apolipoprotein E Polymorphism Impacts White Matter Injury Through Microglial Phagocytosis After Experimental Subarachnoid Hemorrhage.
Lipid-accumulated reactive astrocytes promote disease progression in epilepsy.
FOXP3+ macrophage represses acute ischemic stroke-induced neural inflammation.
Catalpol Regulates Oligodendrocyte Regeneration and Remyelination by Activating the GEF-Cdc42/Rac1 Signaling Pathway in EAE Mice.
ADSCs Combined with Melatonin Promote Peripheral Nerve Regeneration through Autophagy.
Behavioral and Molecular Consequences of Chronic Sleep Restriction During Development in Fragile X Mice.
Effect of β-hydroxybutyrate on behavioral alterations, molecular and morphological changes in CNS of multiple sclerosis mouse model.
Novel recombinant protein flagellin A N/C attenuates experimental autoimmune encephalomyelitis by suppressing the ROS/NF-κB/NLRP3 signaling pathway.
Delivery of Basic Fibroblast Growth Factor Through an In Situ Forming Smart Hydrogel Activates Autophagy in Schwann Cells and Improves Facial Nerves Generation via the PAK-1 Signaling Pathway.
Enhanced effect of combining bone marrow mesenchymal stem cells (BMMSCs) and pulsed electromagnetic fields (PEMF) to promote recovery after spinal cord injury in mice.
HDAC3 Inhibitor RGFP966 Ameliorated Neuroinflammation in the Cuprizone-Induced Demyelinating Mouse Model and LPS-Stimulated BV2 Cells by Downregulating the P2X7R/STAT3/NF-κB65/NLRP3 Activation.
Stemazole Promotes Oligodendrocyte Precursor Cell Survival In Vitro and Remyelination In Vivo.
Ginsenoside Rg1 promotes remyelination and functional recovery in demyelinating disease by enhancing oligodendrocyte precursor cells-mediated myelin repair.
The divergent effects of astrocyte ceruloplasmin on learning and memory function in young and old mice.
Neutrophil Nanovesicle Protects against Experimental Autoimmune Encephalomyelitis through Enhancing Myelin Clearance by Microglia.
Expression and immunogenicity of nsp10 protein of porcine epidemic diarrhea virus.
E3 ubiquitin ligase Triad1 promotes neuronal apoptosis by regulating the p53-caspase3 pathway after spinal cord injury.
SPIONs mediated magnetic actuation promotes nerve regeneration by inducing and maintaining repair-supportive phenotypes in Schwann cells.
Development of a Chemical Cocktail That Rescues Mouse Brain Demyelination in a Cuprizone-Induced Model.
Sensory neurons have an axon initial segment that initiates spontaneous activity in neuropathic pain.
C1q inhibits differentiation of oligodendrocyte progenitor cells via Wnt/β-catenin signaling activation in a cuprizone-induced mouse model of multiple sclerosis.
Rewired glycosylation activity promotes scarless regeneration and functional recovery in spiny mice after complete spinal cord transection.
Preparation, Characterization, Evaluation of Neuroprotective Effect, and Related Mechanisms of Phosphatidylserine Emulsion in 5- and 12-Week Old Mice.
Dose optimization of intrathecal administration of human umbilical cord mesenchymal stem cells for the treatment of subacute incomplete spinal cord injury.
An in vivo implementation of the MEX MRI for myelin fraction of mice brain.
Multifunctional biomimetic hydrogel based on graphene nanoparticles and sodium alginate for peripheral nerve injury therapy.
The microbiota-gut-brain axis participates in chronic cerebral hypoperfusion by disrupting the metabolism of short-chain fatty acids.
Photobiomodulation Therapy Attenuates Anxious-Depressive-Like Behavior in the TgF344 Rat Model.
Connexin43 promotes angiogenesis through activating the HIF-1α/VEGF signaling pathway under chronic cerebral hypoperfusion.
Transfer of α-synuclein from neurons to oligodendrocytes triggers myelin sheath destruction in methamphetamine administration mice.
Maternal high sugar and fat diet benefits offspring brain function via targeting on the gut-brain axis.
A five-m6A regulatory gene signature is a prognostic biomarker in lung adenocarcinoma patients.
A Novel Rat Model with Long Range Optic Nerve Injury to Study Retinal Ganglion Cells Endogenous Regeneration.
Evaluation of cytokines and structural proteins to analyze the pathology of febrile central nervous system disease.
The combined treatment of NAD(+) and atorvastatin ameliorates the development of experimental autoimmune encephalomyelitis in C57BL/6 mice.
Intranasal administration of DHED protects against exhaustive exercise-induced brain injury in rats.
Caffeic Acid Phenethyl Ester Protects against Experimental Autoimmune Encephalomyelitis by Regulating T Cell Activities.
Acupuncture Improves White Matter Perfusion and Integrity in Rat Model of Vascular Dementia: An MRI-Based Imaging Study.
Bixin Attenuates Experimental Autoimmune Encephalomyelitis by Suppressing TXNIP/NLRP3 Inflammasome Activity and Activating NRF2 Signaling.
Subarachnoid transplantation of human umbilical cord mesenchymal stem cell in rodent model with subacute incomplete spinal cord injury: Preclinical safety and efficacy study.
Deficiency of microglial Hv1 channel is associated with activation of autophagic pathway and ROS production in LPC-induced demyelination mouse model.
Sevoflurane anesthesia during pregnancy in mice induces cognitive impairment in the offspring by causing iron deficiency and inhibiting myelinogenesis.
Arsenic trioxide ameliorates experimental autoimmune encephalomyelitis in C57BL/6 mice by inducing CD4(+) T cell apoptosis.
Triclosan induces zebrafish neurotoxicity by abnormal expression of miR-219 targeting oligodendrocyte differentiation of central nervous system.
Amelioration of clinical course and demyelination in the cuprizone mouse model in relation to ketogenic diet.
Chronic Sleep Restriction in Developing Male Mice Results in Long Lasting Behavior Impairments.
Myelin Oligodendrocyte Glycoprotein-IgG Contributes to Oligodendrocytopathy in the Presence of Complement, Distinct from Astrocytopathy Induced by AQP4-IgG.
Integral membrane protein 2A inhibits cell growth in human breast cancer via enhancing autophagy induction.
Mesenchymal Stem Cell-Derived Exosomes Reduce A1 Astrocytes via Downregulation of Phosphorylated NFκB P65 Subunit in Spinal Cord Injury.
Sigma-1 receptor activation alleviates blood-brain barrier dysfunction in vascular dementia mice.
Structural and visual functional deficits in a rat model of neuromyelitis optica spectrum disorders related optic neuritis.
ST8SIA2 promotes oligodendrocyte differentiation and the integrity of myelin and axons.
Protective Effect of 17β-Estradiol Upon Hippocampal Spine Density and Cognitive Function in an Animal Model of Vascular Dementia.
Treatment with NAD(+) inhibited experimental autoimmune encephalomyelitis by activating AMPK/SIRT1 signaling pathway and modulating Th1/Th17 immune responses in mice.
Methylene blue alleviates experimental autoimmune encephalomyelitis by modulating AMPK/SIRT1 signaling pathway and Th17/Treg immune response.
Liu Y, Hu C, He S, Liu R, Zhao Y, Wang Y, Xu H, Li H, Ma Y, Lu B, Ai Y, Ju C, Wu W, Wang Y, Huang D, Hao D, Wang Z, He B, Zhu L
Theranostics 2026;16(1):483-515
Theranostics 2026;16(1):483-515
Ultrasound Activated Piezoelectric Dural Patches to Drive Endogenous Neural Stem Cell-Mediated Repair Traumatic Brain Injury.
Zhou P, Wu Q, Wu Y, Huang R, Li W, Niu H, Sun H, Liu H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(27):e24326
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(27):e24326
Small extracellular vesicles derived from hair follicle neural crest stem cells enhance perineurial cell proliferation and migration via the TGF-β/SMAD/HAS2 pathway.
Huo Y, Xiao B, Yu H, Xu Y, Zheng J, Huang C, Wang L, Lin H, Xu J, Yang P, Liu F
Neural regeneration research 2026 May 1;21(5):2060-2072
Neural regeneration research 2026 May 1;21(5):2060-2072
Clemastine ameliorates cognitive deficits in an experimental rat model of chronic cerebral hypoperfusion.
Zong X, Huang Z, Kong F, Feng Y, Zhang Y, Zou P, Wen Lin H, Hess DC, Zhang Q
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2026 Mar;46(3):786-803
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2026 Mar;46(3):786-803
FUNDC1-dependent mitophagy determines axon regeneration capacity.
Li W, Liu Y, Liu R, Fan Y, Liu J, Guo Y, Hu Z, Liu L, Chen Q, Zhou B
Autophagy 2026 Jun;22(6):1256-1272
Autophagy 2026 Jun;22(6):1256-1272
Bone marrow mesenchymal stem cells protect against cerebral amyloid angiopathy by enhancing neutrophil mitocytosis.
Hu M, Yi H, Wang S, Kang X, Liu Y, Liu Z, Huang H, Qin Q, Yuan L, Cai W, Qiu W, Lu Z, Liu S
Neural regeneration research 2026 Jul 1;21(7):3178-3186
Neural regeneration research 2026 Jul 1;21(7):3178-3186
Fibrinogen contributes to myelin deficit and cognitive impairment in aged mice after anesthesia and surgery.
Wang X, Jiang S, Cao T, Huang P, Di L, Li J, Huang L
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2026 Jan;46(1):105-117
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2026 Jan;46(1):105-117
Salidroside ameliorates experimental autoimmune neuritis by dually modulating neuroinflammation and immune homeostasis via PI3K/AKT signaling.
Gu T, Wang L, Kang X, Yu C, Shen K, Song M, Gao Y, Wang G, Wang Z
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Jan;23(1):e00769
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Jan;23(1):e00769
Thermodynamic Delivery of Trehalose into Extracellular Vesicles for Enhanced Lyophilization.
Wang T, Fu Y, Yu B, Dang W, Ji M, Jian Z, Ding J, Zhang G, Huang H
Advanced healthcare materials 2026 Jan;15(3):e00522
Advanced healthcare materials 2026 Jan;15(3):e00522
The effect of 807-nm light-emitting diode photobiomodulation on peripheral nerve injury.
Chang B, Quan Q, Liang X, Guan Y, Xiong X, Qiu H, Zeng J, Liu Y, Wang Y, Peng J, Gu Y
Photochemistry and photobiology 2026 Jan-Feb;102(1):207-219
Photochemistry and photobiology 2026 Jan-Feb;102(1):207-219
Rewiring brain structural and functional disconnection with acupuncture in rat model of vascular cognitive impairment and dementia.
Wang L, Zhao JP, Cao Y, Ma SM, Yang JW, Su XT, Huang J, Wang QY, Liu CZ
Biological research 2026 Jan 19;59(1):10
Biological research 2026 Jan 19;59(1):10
Puerarin Attenuates White Matter Injury and Blood-Brain Barrier Disruption After Intracerebral Hemorrhagic Stroke via cGAS-STING Axis.
Ouyang Y, Yu L, Shi Y, Chen Z, Tang X, Jin J, Huang Z, Tang X, Zhu B, Wang X
Biology 2026 Feb 3;15(3)
Biology 2026 Feb 3;15(3)
Activation status of astrocytes drives the MS/NMOSD therapeutic paradox: Insights from IFNAR1 signaling.
Dai L, Cheng G, Cui T, He S, Wang R, Kang J, Li P, Zhang X, Ding X, Xue X, Yang L, Zhang Y, Yan Y
Cell reports 2026 Feb 24;45(2):116913
Cell reports 2026 Feb 24;45(2):116913
EGCG-loaded nanoparticles attenuate post-SAH white matter injury by targeting HO-1/S100A10 to suppress oxidative stress-induced reactive astrocytes.
Lang D, Zheng Y, Zhang J, Li Z, Niu M, Wang J, Wang X, Huang L, Xue J, Li L, Chen Y
Redox report : communications in free radical research 2026 Dec 31;31(1):2664955
Redox report : communications in free radical research 2026 Dec 31;31(1):2664955
Engineered exosomes mediated siNox4 delivery loaded polyzwitterionic hydrogel with electrophysiologic conductivity for synergistic treatment of spinal cord injury via suppressing neuronal ferroptosis.
Wu C, Tang Y, Jiang Z, Hong C, Yang Q, Wu Z, Zhu J, Guo K, Liu J, Zheng SY, Guo L, Xu H, Ni W, Wang X, Sheng S, Xiao J, Wang C
Biomaterials 2026 Aug;331:124096
Biomaterials 2026 Aug;331:124096
Tianwang Buxin Pill improves cognitive function in APP/PS1 mice by reducing neuronal damage and regulating synaptic plasticity.
Zou F, Ren X, Huo G, Liu P, Sun C
Journal of ethnopharmacology 2026 Aug 10;367:121683
Journal of ethnopharmacology 2026 Aug 10;367:121683
Resveratrol Attenuates Neuroinflammation and Myelination Deficits in Repeated Sevoflurane-Exposed Neonatal Mice.
Che J, Wu Y, Dong J, Shi C, Chen Y, He Z, Zhang X, Zhang J
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2026 Apr;86(2):e70123
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2026 Apr;86(2):e70123
Self-cleavage-dependent and -independent functions of Adgrg1/Gpr56 in mice.
Kwarcinski FE, Bernadyn TF, Teuber JP, Nascimento M, Bergin I, Shen T, Gandhi R, Lu X, Brody MJ, Holinstat M, Tall GG
Proceedings of the National Academy of Sciences of the United States of America 2026 Apr 28;123(17):e2527832123
Proceedings of the National Academy of Sciences of the United States of America 2026 Apr 28;123(17):e2527832123
IMR-1 ameliorates perinatal LPS-induced brain injury by promoting the conversion of glial cells into neurons.
Tang J, Zhou S, Zhang Z, Duan B, Xu Y
Journal of molecular histology 2026 Apr 27;57(3)
Journal of molecular histology 2026 Apr 27;57(3)
KDM2B-PP1 Promotes Remyelination and Functional Recovery After Facial Nerve Injury.
Xu H, Yang H, Cao Y, Fan Z
Journal of oral rehabilitation 2026 Apr 24;
Journal of oral rehabilitation 2026 Apr 24;
Repetitive Trans-spinal Magnetic Stimulation Suppresses Microglia to Engulf Synapse and Promotes Nerve Repairment via cGAS-STING Signaling Pathway after Spinal Cord Injury.
Huang M, Di J, Li N, Xiao L, Tian Z, He T, Pang M, Liu B, He L, Rong L
International journal of biological sciences 2025;21(14):6132-6155
International journal of biological sciences 2025;21(14):6132-6155
Validation of a data-driven multicomponent T2 analysis for quantifying myelin content in the cuprizone mouse model of multiple sclerosis.
Omer N, Wilczynski E, Zlotzover S, Helft C, Blumenfeld-Katzir T, Ben-Eliezer N
PloS one 2025;20(5):e0323614
PloS one 2025;20(5):e0323614
TRIM37-mediated stabilization of PEX5 via monoubiquitination attenuates oxidative stress and demyelination in multiple sclerosis insights from EAE and LPC-induced experimental models.
Jiang L, Jin Y, Han Y, Fu J
PloS one 2025;20(10):e0335198
PloS one 2025;20(10):e0335198
Injectable ion-coordinated double-network conductive hydrogel for spinal cord injury repair.
Yu H, Liu F, Hu Y, Wan W, Liu Q, Zhou S, Zhang L, Li L, Huang F
Frontiers in bioengineering and biotechnology 2025;13:1618680
Frontiers in bioengineering and biotechnology 2025;13:1618680
Targeting the miR-96-5p/Cathepsin B Pathway to Alleviate Neuron-Derived Neuroinflammation in Alzheimer's Disease.
Zheng K, Huang HZ, Liu D, Brazhe N, Chen J, Zhu LQ
MedComm 2025 Sep;6(9):e70368
MedComm 2025 Sep;6(9):e70368
The role of astrocyte-derived extracellular vesicles in cellular microenvironment remodeling after spinal cord injury: A study based on quantitative proteomics analysis.
Zhu Z, Xu Y, Wang K, Xu X, Song Y, Zhao B, Ding W, Liu J, Song Z
Experimental neurology 2025 Sep;391:115321
Experimental neurology 2025 Sep;391:115321
Furongtongmai capsule alleviates neuroinflammation by downregulating the TLR4/MyD88/JNK pathway to promote the recovery of peripheral nerve compression.
Liu H, Zhang X, Gu Q, Zhao Y, Wang H, Li H, Zhou T, Zhang Y, Zhao J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157082
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157082
A Myelin Debris Cleaner for Spinal Cord Injury Recovery: Polycaprolactone / Cell Membrane Assembled Scaffolds.
Zhou Y, Xu T, Zhou Y, Chen N, Wu Z, Yang Z, Yang C, Chen X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(36):e03269
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(36):e03269
Oligodendrocyte-specific knockout of FPN1 affects CNS myelination defects and depression-like behavior in mice.
Zhang N, Zhang S, Liu X, Zuo YY, Cui YG, Wang F, Zhang JH, Chang YZ, Yu P
Free radical biology & medicine 2025 Oct;238:370-386
Free radical biology & medicine 2025 Oct;238:370-386
Neonatal sevoflurane exposure disrupted fatty acids metabolism, leading to hypomyelination and neurological impairments.
Jiang S, Cao T, Li J, Di L, Wang X, Xie Z, Huang L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Oct;191:118495
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Oct;191:118495
Poliumoside Alleviates Neuroinflammation and Oxidative Stress After Spinal Cord Injury by Activating the PI3K/AKT/mTOR Signaling Pathway.
Li Q, Hong H, Xu G, Xia M, Wang T, Zhou Z, Huang J, Fu Q, Cui Z
Journal of integrative neuroscience 2025 Oct 29;24(10):43900
Journal of integrative neuroscience 2025 Oct 29;24(10):43900
Photobiomodulation as a therapeutic approach for attention-deficit/hyperactivity disorder in model rats.
Huang YJ, Li YT, Tsai ML, Lee FC, Niwa A, Yen CH, Chu CY, Chang H
Lasers in medical science 2025 Oct 10;40(1):417
Lasers in medical science 2025 Oct 10;40(1):417
Sex-dependent impairments in oligodendrocyte maturation and myelination in offspring mice exposed to preeclampsia.
Wu Z, Qiu Y, Chen X, Xia Z, Lv J, Jia Y, Xue H, Zhao P
Experimental neurology 2025 Nov;393:115405
Experimental neurology 2025 Nov;393:115405
Hepcidin/HIF-1α is involved in the endogenous recovery and ferroptosis after cerebral ischemia in mice.
Zhao J, Dong L, Gong X, Hui S, Wang X, Tian S, Liu Y, Huo T, Xie Y, Chang Y
Biochimica et biophysica acta. Molecular basis of disease 2025 Nov;1871(8):168022
Biochimica et biophysica acta. Molecular basis of disease 2025 Nov;1871(8):168022
Dual Mechanisms of Cognitive Function and Pathological Improvements by the Selective S1PR1/5 Modulator Siponimod in 3xTg-AD Mice.
Tang C, Ding Y, Yang S, Lei X, Zhang M, Xu B, He D
Molecular neurobiology 2025 Nov 22;63(1):133
Molecular neurobiology 2025 Nov 22;63(1):133
Hydroxylation of HPPD facilitates its PUB11-mediated ubiquitination and degradation in response to oxidative stress in Arabidopsis.
Yu XH, Wen X, Dong J, Hu YF, Wang XL, Zhu DY, Ling Q, Lin HY, Yang GF
Plant communications 2025 Nov 10;6(11):101521
Plant communications 2025 Nov 10;6(11):101521
Divergent MYB paralogs determine spatial distribution of linalool mediated by JA and DNA demethylation participating in aroma formation and cold tolerance of tea plants.
Yue R, Li Y, Qi Y, Liang X, Zheng Z, Ye Z, Tong W, Si X, Zhang Y, Xia E, Li P
Plant biotechnology journal 2025 May;23(5):1455-1475
Plant biotechnology journal 2025 May;23(5):1455-1475
Pad2 deletion induces anxiety‑like behaviors and memory deficits in mice.
Lv X, Deng H, Li C, Gao W, Zhang Y, Gao Y, Zhao B, Shi C, Gao J, Liu Z
Brain research bulletin 2025 May;224:111327
Brain research bulletin 2025 May;224:111327
Single-cell and spatial transcriptomics analysis reveals that Pros1(+) oligodendrocytes are involved in endogenous neuroprotection after brainstem stroke.
Li S, Zeng G, Pang C, Li J, Wu L, Luo M, Qiu Z, Jiang Y
Neurobiology of disease 2025 May;208:106855
Neurobiology of disease 2025 May;208:106855
SETD3-mediated histidine methylation of MCM7 regulates DNA replication by facilitating chromatin loading of MCM.
Duan H, Wang S, Shu WJ, Tong Y, Long HZ, Li G, Du HN, Zhao MJ
Science China. Life sciences 2025 Mar;68(3):793-808
Science China. Life sciences 2025 Mar;68(3):793-808
Inhibition of histamine receptor 3 alleviates sevoflurane-induced hypomyelination and neurobehavioral deficits.
Che J, Wu Y, Dong J, Jiang X, Yang L, Chen Y, Zhang J
Experimental neurology 2025 Mar;385:115086
Experimental neurology 2025 Mar;385:115086
Puerarin mitigates cognitive decline and white matter injury via CD36-Mediated microglial phagocytosis in chronic cerebral hypoperfusion.
Luo Q, Li F, Liu X, Yan T, Yang L, Zhu W, Zheng H, Li Y, Tu J, Zhu X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Mar;138:156396
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Mar;138:156396
Myelination Trajectory and Microglial Dynamics Following Repeated Sevoflurane Exposure in Developing Brain.
Che J, Wu Y, Dong J, Jiang X, Yang L, Chen Y, Zhang J
Glia 2025 Jun;73(6):1221-1240
Glia 2025 Jun;73(6):1221-1240
Activation of GPER1 alleviates white matter injury by promoting microglia M2 polarization through EGFR/Stat3 pathway in intracerebral hemorrhage mice.
Zhang X, Mao J, Li H, Zhang C, Ge H, Zhong J
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2025 Jun;34(6):108315
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2025 Jun;34(6):108315
Single-Cell RNA Sequencing and Spatial Transcriptomics Reveal a Novel Mechanism of Oligodendrocyte-Neuron Interaction in Cognitive Decline After High-Altitude Cerebral Edema.
Lv W, Ma Y, Li D, Xiong K, Cui J, Pan S, Zhang N, Li Y, Chen Y, Guo D
CNS neuroscience & therapeutics 2025 Jun;31(6):e70485
CNS neuroscience & therapeutics 2025 Jun;31(6):e70485
Exercise-induced irisin ameliorates cognitive impairment following chronic cerebral hypoperfusion by suppressing neuroinflammation and hippocampal neuronal apoptosis.
Xiao W, Yang Y, Bai L, Yang P, Li R, Yang D, Li F, Quan L, Liang Q, Yan Y, Qi T, Liang F
Journal of neuroinflammation 2025 Jun 28;22(1):168
Journal of neuroinflammation 2025 Jun 28;22(1):168
Salidroside Exerts Neuroprotective Effects via Inhibiting Ferroptosis in Mice with Traumatic Brain Injury.
Huang Y, He Y, Zhao X, Zou Y, Ding W, Wei L
Neurochemical research 2025 Jun 21;50(4):204
Neurochemical research 2025 Jun 21;50(4):204
Pro-repair macrophages driven by CGRP rescue white matter integrity following intracerebral hemorrhage.
Huang H, Kuang Y, Chen Y, Zhang Y, Zhou J, Yu X, Zheng Y, Cai L, Hu W, Gao L, Wu H, Ling H, Dong X, Zhou H, Yu X, Peng Y, Chen G, Wang X, Yan W
Journal of neuroinflammation 2025 Jun 21;22(1):161
Journal of neuroinflammation 2025 Jun 21;22(1):161
FOXP3(+) Macrophage-Derived Amphiregulin Promotes White Matter Repair of Experimental Autoimmune Encephalomyelitis.
Wu S, Shen S, Sun W, Zhao Y, Zhang J, Wang Z, Cai W, Lu Z, Qiu W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 15;39(11):e70719
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 15;39(11):e70719
Combined enriched environment and fluoxetine enhance myelin protein expression in the prefrontal cortex of a chronic unpredictable stress depression model.
Gu J, Liu C, Li Y, Feng L, Geng M, Dong J, Han J, Zhao L, Shao Q, Wang HY, Wang CH
Behavioral and brain functions : BBF 2025 Jun 11;21(1):16
Behavioral and brain functions : BBF 2025 Jun 11;21(1):16
Optimally Aligned Nerve Scaffolds with Sustained Astaxanthin Release Improve the Inflammatory Microenvironment through Mitophagy Activation.
Jin X, Liu S, Fang J, Chen F, Xu B, Nan L, Zhao S, Wu Z, Guan Z, Tao K, Liu J
Small (Weinheim an der Bergstrasse, Germany) 2025 Jul;21(26):e2502939
Small (Weinheim an der Bergstrasse, Germany) 2025 Jul;21(26):e2502939
The circadian clock module LgPRR7-LgFKF1 negatively regulates flowering time in Luculia gratissima, a woody ornamental plant.
Liu X, Wan Y, Wang J, Gao F, Wu Z, Li Z, Zhang Y, Ma Y, Ma H
Horticulture research 2025 Jul;12(7):uhaf110
Horticulture research 2025 Jul;12(7):uhaf110
Oligodendrocyte-Specific STAT5B Overexpression Ameliorates Myelin Impairment in Experimental Models of Parkinson's Disease.
Li Y, Su Z, Zhai J, Liu Q, Wang H, Hao J, Tian X, Gao J, Geng D, Wang L
Cells 2025 Jul 25;14(15)
Cells 2025 Jul 25;14(15)
The Upregulation of L1CAM by SVHRSP Mitigates Neuron Damage, Spontaneous Seizures, and Cognitive Dysfunction in a Kainic Acid-Induced Rat Model of Epilepsy.
Li Z, Ge B, Li H, Huang C, Ji Y, Schachner M, Yin S, Li S, Zhao J
Biomolecules 2025 Jul 17;15(7)
Biomolecules 2025 Jul 17;15(7)
Glutamate chemical exchange saturation transfer (GluCEST) MRI to evaluate the relationship between demyelination and glutamate content in depressed mice.
Qi K, Li H, Tao J, Liu M, Zhang W, Liu Y, Liu Y, Gong H, Wei J, Wang A, Xu J, Li X
Behavioural brain research 2025 Jan 5;476:115247
Behavioural brain research 2025 Jan 5;476:115247
Lipidomics Analysis Reveals the Effects of Docosahexaenoic Acid from Different Sources on Prefrontal-Cortex Synaptic Plasticity.
He Z, Xiong W, Yang Y, Zhang Y, Li B, Wang F, Li Y, Wang R, Sun Y
Nutrients 2025 Jan 27;17(3)
Nutrients 2025 Jan 27;17(3)
TDP43 augments astrocyte inflammatory activity through mtDNA-cGAS-STING axis in NMOSD.
Liu Z, Bai Y, Xu B, Wen H, Chen K, Lin J, Wang Y, Xu J, Wang H, Shi F, Wang J, Wang H
Journal of neuroinflammation 2025 Jan 22;22(1):14
Journal of neuroinflammation 2025 Jan 22;22(1):14
Rosiglitazone Promotes Oligodendrocyte Development and Myelin Formation of Repeated Neonatal Sevoflurane Exposure via PPARγ Signaling.
Cao T, Jiang S, Wang X, Huang P, Zhou L, Di L, Han S, Huang L
Molecular neurobiology 2025 Feb;62(2):2348-2361
Molecular neurobiology 2025 Feb;62(2):2348-2361
Intra-cisterna-magna bevacizumab injection (ICM-BI) reproduces pathological alterations of cerebral small vessel diseases.
Kang X, Su X, Li T, Wang S, Huang H, Liu Y, Li C, Deng X, Hu M, Lu T, Wei L, Cai W, Lu Z
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2025 Feb;45(2):244-258
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2025 Feb;45(2):244-258
Activation of PAR1 contributes to ferroptosis of Schwann cells and inhibits regeneration of myelin sheath after sciatic nerve crush injury in rats via Hippo-YAP/ACSL4 pathway.
Wu Z, Sun J, Liao Z, Sun T, Huang L, Qiao J, Ling C, Chen C, Zhang B, Wang H
Experimental neurology 2025 Feb;384:115053
Experimental neurology 2025 Feb;384:115053
Kaempferol attenuates experimental autoimmune neuritis through TNFR1/JNK/p38 signaling pathway inhibition.
Wang L, Gu T, Yu C, Gao Y, Xuan T, Shen K, Wang G, Wang Z
International immunopharmacology 2025 Feb 6;147:113951
International immunopharmacology 2025 Feb 6;147:113951
Mesenchymal stem cells overexpressing neuropeptide S promote the recovery of rats with spinal cord injury by activating the PI3K/AKT/GSK3β signaling pathway.
Yang W, Li Y, Tang Y, Tao Z, Yu M, Sun C, Ye Y, Xu B, Zhao X, Zhang Y, Lu X
Stem cell research & therapy 2025 Feb 28;16(1):100
Stem cell research & therapy 2025 Feb 28;16(1):100
Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons.
Costa AC, Murillo BR, Bessa R, Ribeiro R, Ferreira da Silva T, Porfírio-Rodrigues P, Martins GG, Brites P, Kneussel M, Misgeld T, Brill MS, Sousa MM
eLife 2025 Feb 24;13
eLife 2025 Feb 24;13
Neonatal sevoflurane exposures inhibits DHHC5-mediated palmitoylation of TfR1 in oligodendrocytes, leading to hypomyelination and neurological impairments.
Liu H, Su B, Zhang Z, Jia S, Wang J, Zhou F, Liu Y, Cao Q, Tang J, Ou Z, Zhang MM, Chen Y, Dong H, Zhong H
Journal of advanced research 2025 Dec;78:471-485
Journal of advanced research 2025 Dec;78:471-485
Prospero-related homeobox protein 1 (Prox1) enhances myelin sheath regeneration in injured sciatic nerve.
Jie L, Jing X, Liu J, Ren J, Kong X, Wu J, Meng F
IBRO neuroscience reports 2025 Dec;19:679-687
IBRO neuroscience reports 2025 Dec;19:679-687
Saracatinib Promotes Hippocampal Myelin Regeneration and Oligodendrocyte Precursor Cell Maturation by Inhibiting the NOTCH1 Signaling Pathway in Epileptic Mice.
Luo X, Wu W, Yu B, Chen S, Zhao J, Min J, Gu X
Neurochemical research 2025 Dec 9;51(1):11
Neurochemical research 2025 Dec 9;51(1):11
Transcript Imbalance from TENM4 Exon Skipping: Effects on Epilepsy and Genetic Pleiotropy.
Suzuki Y, Uehara DT, Enokido Y, Kawai T, Nomura N, Yamada K, Takanashi JI, Miyahara H, Inazawa J, Hayashi S
Molecular neurobiology 2025 Dec 26;63(1):324
Molecular neurobiology 2025 Dec 26;63(1):324
Ferroptosis is a novel pathogenic mechanism of FDXR-related disease via disruption of the NRF2 pathway.
Campbell T, Slone J, Vu J, Liu W, Yang L, Dourson A, Queme LF, Jankowski MP, Huang T
Cell death discovery 2025 Dec 23;11(1):563
Cell death discovery 2025 Dec 23;11(1):563
The Neuroprotective Effect of 4-Octyl Itaconate on Acute Period of Experimental Autoimmune Neuritis.
Zhang LJ, Zhao N, Li J, Zhai H, Wu J, Yang L
Inflammation 2025 Dec 17;49(1):5
Inflammation 2025 Dec 17;49(1):5
Upregulating mTOR/S6 K Pathway by CASTOR1 Promotes Astrocyte Proliferation and Myelination in Gpam(-/-)-induced mouse model of cerebral palsy.
Chen Z, Liu L, Guo X, Zhang Y, Zhong M, Xu Y, Peng T Sr, Peng T Jr, Zhang Y, Hou Q, Fan D, Gao T, He L, Tang H, Hu H, Xu K
Molecular neurobiology 2025 Aug;62(8):10724-10741
Molecular neurobiology 2025 Aug;62(8):10724-10741
Diosgenin promoted OPCs differentiation via blocking GLUR2/GAPDH interaction in a pilocarpine rat model of epilepsy.
Gao Z, Wang L, Lai Q, Liu Y, Wang S, Liu J, Feng Z, Liu H, Yao R
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Aug;144:156921
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Aug;144:156921
The foam cell-derived exosomes exacerbate ischemic white matter injury via transmitting metabolic defects to microglia.
Zhang H, Zhou LQ, Yang S, Dong MH, Chen L, Lu YL, Zhang LY, Zhang L, Chu YH, Xu LL, Pang XW, Zhu LF, Xu T, Yong TY, Wang W, Tian DS, Qin C
Cell metabolism 2025 Aug 5;37(8):1636-1654.e10
Cell metabolism 2025 Aug 5;37(8):1636-1654.e10
Preventive and therapeutic effects of Tanshinone IIA on spinal cord injury without radiographic abnormality by regulating microglial phenotype polarization.
Xu L, Ma Y, Jiang G, Cao Z, Song J, Gao Y, Wang G, Fan J, Yang Y, Yu X
International immunopharmacology 2025 Aug 28;161:115086
International immunopharmacology 2025 Aug 28;161:115086
Electroacupuncture Protects Against Post-stroke Cognitive Impairment by Promoting an IL-33/ST2 Axis-Mediated Microglia M2 Polarization.
Zhang Y, Ding Z, Wang Y, Liu H, Gao J, Wang H, Wu M, Feng X, Shen X
Neurochemical research 2025 Aug 13;50(4):261
Neurochemical research 2025 Aug 13;50(4):261
Dexmedetomidine Improves Long-term Neurological Outcomes by Promoting Oligodendrocyte Genesis and Myelination in Neonatal Rats Following Hypoxic-ischemic Brain Injury.
Xue H, Ding Z, Chen X, Yang X, Jia Y, Zhao P, Wu Z
Molecular neurobiology 2025 Apr;62(4):4866-4880
Molecular neurobiology 2025 Apr;62(4):4866-4880
FGF21 Alleviates Hypoxic-Ischemic White Matter Injury in Neonatal Mice by Mediating Inflammation and Oxidative Stress Through PPAR-γ Signaling Pathway.
Fang M, Lu L, Lou J, Ou J, Yu Q, Tao X, Zhu J, Lin Z
Molecular neurobiology 2025 Apr;62(4):4743-4768
Molecular neurobiology 2025 Apr;62(4):4743-4768
Double-target magnetic stimulation attenuates oligodendrocyte apoptosis and oxidative stress impairment after spinal cord injury via GAP43.
Huang M, Di J, He L, Li N, Tian Z, Xiao L, Zhu R, He T, Pang M, Liu B, Rong L
The spine journal : official journal of the North American Spine Society 2025 Apr;25(4):820-842
The spine journal : official journal of the North American Spine Society 2025 Apr;25(4):820-842
Ubiquitination-mediated upregulation of glycolytic enzyme MCT4 in promoting astrocyte reactivity during neuroinflammation.
Yang L, Hu C, Chen X, Sun M, Zhang J, Feng Z, Cui T, Zhu R, Zhang X, Xiao Y, Gong Y, Yang Y, Zhang Q, Zhang Y, Yan Y
Journal of neuroinflammation 2025 Apr 30;22(1):126
Journal of neuroinflammation 2025 Apr 30;22(1):126
The Influence of Pathological Extracellular Matrix on the Biological Properties of Stem Cells: Possible Hints for Cell Transplantation Therapies in Spinal Cord Injury.
Alastra G, Quadalti C, Baldassarro VA, Giuliani A, Giardino L, Calzà L
International journal of molecular sciences 2025 Apr 23;26(9)
International journal of molecular sciences 2025 Apr 23;26(9)
VEGF secreted by human dental pulp stem cell promotes spinal cord injury repair by inhibiting microglial pyroptosis through the PI3K/AKT pathway.
Zhang X, Liu T, Ma Z, Li G, Ding N, Wang Z, Guan Y, Zhang Y, Liu L, Chen X
Journal of translational medicine 2025 Apr 12;23(1):437
Journal of translational medicine 2025 Apr 12;23(1):437
Hypoxic Bone Mesenchymal Stem Cell-Derived Exosomes Direct Schwann Cells Proliferation, Migration, and Paracrine to Accelerate Facial Nerve Regeneration via circRNA_Nkd2/miR-214-3p/MED19 Axis.
Wang H, Zhao H, Chen Z, Cai X, Wang X, Zhou P, Tang Y, Ying T, Zhang X, Shen Y, Wang B, Zhu W, Zhu J, Wang X, Li S
International journal of nanomedicine 2024;19:1409-1429
International journal of nanomedicine 2024;19:1409-1429
Microglia aggravate white matter injury via C3/C3aR pathway after experimental subarachnoid hemorrhage.
Yang L, Wu J, Zhang F, Zhang L, Zhang X, Zhou J, Pang J, Xie B, Xie H, Jiang Y, Peng J
Experimental neurology 2024 Sep;379:114853
Experimental neurology 2024 Sep;379:114853
The RhoB p.S73F mutation leads to cerebral palsy through dysregulation of lipid homeostasis.
Wu X, Liu R, Zhang Z, Yang J, Liu X, Jiang L, Fang M, Wang S, Lai L, Song Y, Li Z
EMBO molecular medicine 2024 Sep;16(9):2002-2023
EMBO molecular medicine 2024 Sep;16(9):2002-2023
Enhancing facial nerve regeneration with scaffold-free conduits engineered using dental pulp stem cells and their endogenous, aligned extracellular matrix.
Drewry MD, Shi D, Dailey MT, Rothermund K, Trbojevic S, Almarza AJ, Cui XT, Syed-Picard FN
Journal of neural engineering 2024 Sep 17;21(5)
Journal of neural engineering 2024 Sep 17;21(5)
Upregulated expression of ubiquitin ligase TRIM21 promotes PKM2 nuclear translocation and astrocyte activation in experimental autoimmune encephalomyelitis.
Yang L, Hu C, Chen X, Zhang J, Feng Z, Xiao Y, He W, Cui T, Zhang X, Yang Y, Zhang Y, Yan Y
eLife 2024 Sep 12;13
eLife 2024 Sep 12;13
An injectable decellularized extracellular matrix hydrogel with cortical neuron-derived exosomes enhances tissue repair following traumatic spinal cord injury.
Wang G, Li Q, Liu S, Li M, Liu B, Zhao T, Liu B, Chen Z
Materials today. Bio 2024 Oct;28:101250
Materials today. Bio 2024 Oct;28:101250
The Neuroprotective Mechanisms of PPAR-γ: Inhibition of Microglia-Mediated Neuroinflammation and Oxidative Stress in a Neonatal Mouse Model of Hypoxic-Ischemic White Matter Injury.
Fang M, Yu Q, Ou J, Lou J, Zhu J, Lin Z
CNS neuroscience & therapeutics 2024 Nov;30(11):e70081
CNS neuroscience & therapeutics 2024 Nov;30(11):e70081
Construction of functional neural network tissue combining CBD-NT3-modified linear-ordered collagen scaffold and TrkC-modified iPSC-derived neural stem cells for spinal cord injury repair.
Wu Z, Zhou Y, Hou X, Liu W, Yin W, Wang L, Cao Y, Jiang Z, Guo Y, Chen Q, Xie W, Wang Z, Shi N, Liu Y, Gao X, Luo L, Dai J, Ren C, Jiang X
Bioactive materials 2024 May;35:242-258
Bioactive materials 2024 May;35:242-258
Nerve Guide Conduits Integrated with Fisetin-Loaded Chitosan Hydrogels for Reducing Oxidative Stress, Inflammation, and Nerve Regeneration.
Fang J, Xu B, Jin X, Chen F, Liu S, Liu S, Wang S, Zhang F, Song K, Wang J, Nan L, Liu J
Macromolecular bioscience 2024 May;24(5):e2300476
Macromolecular bioscience 2024 May;24(5):e2300476
Conditioned medium from human dental pulp stem cells treats spinal cord injury by inhibiting microglial pyroptosis.
Liu T, Ma Z, Liu L, Pei Y, Wu Q, Xu S, Liu Y, Ding N, Guan Y, Zhang Y, Chen X
Neural regeneration research 2024 May;19(5):1105-1111
Neural regeneration research 2024 May;19(5):1105-1111
Protective effect of alirocumab, a PCSK9 inhibitor, on the sciatic nerve of rats with diabetic peripheral neuropathy.
Cui N, Feng Y, Wang M, Lu X, Huang Y, Chen Y, Shi X
Endocrine journal 2024 Mar 28;71(3):233-244
Endocrine journal 2024 Mar 28;71(3):233-244
Enhancing axonal myelination: Clemastine attenuates cognitive impairment in a rat model of diffuse traumatic brain injury.
Huang Z, Feng Y, Zhang Y, Ma X, Zong X, Jordan JD, Zhang Q
Translational research : the journal of laboratory and clinical medicine 2024 Jun;268:40-50
Translational research : the journal of laboratory and clinical medicine 2024 Jun;268:40-50
Exogenous NADPH could mitigate pyroptosis-induced brain injury in fetal mice exposed to gestational intermittent hypoxia.
Wei J, Zheng W, Teng C, An X, Li L, Zhong P, Peng C, Zhuge S, Akoto Ampadu J, Yu C, Cai X
International immunopharmacology 2024 Jun 30;135:112311
International immunopharmacology 2024 Jun 30;135:112311
Selective bioaccumulation of polystyrene nanoplastics in fetal rat brain and damage to myelin development.
Zhang Y, Tian L, Chen J, Liu X, Li K, Liu H, Lai W, Shi Y, Lin B, Xi Z
Ecotoxicology and environmental safety 2024 Jun 15;278:116393
Ecotoxicology and environmental safety 2024 Jun 15;278:116393
Circadian misalignment impairs oligodendrocyte myelination via Bmal1 overexpression leading to anxiety and depression-like behaviors.
Zuo Y, Hou Y, Wang Y, Yuan L, Cheng L, Zhang T
Journal of pineal research 2024 Jan;76(1):e12935
Journal of pineal research 2024 Jan;76(1):e12935
Matrine Mediated Immune Protection in MS by Regulating Gut Microbiota and Production of SCFAs.
Dou M, Chu Y, Zhou X, Wang M, Li X, Ma R, Fan Z, Zhao X, Wang W, Li S, Lv Y, Zhu L
Molecular neurobiology 2024 Jan;61(1):74-90
Molecular neurobiology 2024 Jan;61(1):74-90
Clemastine-induced enhancement of hippocampal myelination alleviates memory impairment in mice with chronic pain.
Zhu TT, Wang H, Liu PM, Gu HW, Pan WT, Zhao MM, Hashimoto K, Yang JJ
Neurobiology of disease 2024 Jan;190:106375
Neurobiology of disease 2024 Jan;190:106375
A High MCT-Based Ketogenic Diet Suppresses Th1 and Th17 Responses to Ameliorate Experimental Autoimmune Encephalomyelitis in Mice by Inhibiting GSDMD and JAK2-STAT3/4 Pathways.
Zhang Q, Sun W, Wang Q, Zheng X, Zhang R, Zhang N
Molecular nutrition & food research 2024 Feb;68(3):e2300602
Molecular nutrition & food research 2024 Feb;68(3):e2300602
Targeting Ferroptosis Promotes Functional Recovery by Mitigating White Matter Injury Following Acute Carbon Monoxide Poisoning.
Wang S, Xiong B, Tian Y, Hu Q, Jiang X, Zhang J, Chen L, Wang R, Li M, Zhou X, Zhang T, Ge H, Yu A
Molecular neurobiology 2024 Feb;61(2):1157-1174
Molecular neurobiology 2024 Feb;61(2):1157-1174
Sevoflurane causes cognitive impairment by inducing iron deficiency and inhibiting the proliferation of neural precursor cells in infant mice.
Zuo Y, Xie J, Zhang X, Thirupathi A, Liu X, Zhang D, Zhang J, Shi Z
CNS neuroscience & therapeutics 2024 Feb;30(2):e14612
CNS neuroscience & therapeutics 2024 Feb;30(2):e14612
Combining PLGA microspheres loaded with Liver X receptor agonist GW3965 with a chitosan nerve conduit can promote the healing and regeneration of the wounded sciatic nerve.
Zhong Y, Li S, Chen Y, Tang Y, Xiao X, Nie T
Journal of biomedical materials research. Part B, Applied biomaterials 2024 Feb;112(2):e35378
Journal of biomedical materials research. Part B, Applied biomaterials 2024 Feb;112(2):e35378
Complanatuside A improves functional recovery after spinal cord injury through inhibiting JNK signaling-mediated microglial activation.
Xu Y, Geng Z, Sun Y, Zhu G, Xiao L, Wang Z, Li B, Liu X, Shi J, Song X, Hu J, Qi Q
European journal of pharmacology 2024 Feb 15;965:176287
European journal of pharmacology 2024 Feb 15;965:176287
Agomelatine promotes differentiation of oligodendrocyte precursor cells and preserves white matter integrity after cerebral ischemic stroke.
Wang S, Li C, Kang X, Su X, Liu Y, Wang Y, Liu S, Deng X, Huang H, Li T, Lu D, Cai W, Lu Z, Wei L, Lu T
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2024 Dec;44(12):1487-1500
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2024 Dec;44(12):1487-1500
Temporal dynamics of neutrophil functions in multiple sclerosis.
Shen S, Wu S, Wang Y, Xiao L, Sun X, Sun W, Zhao Y, Li R, Zhang J, Wang Z, Zhou S, Huang S, Chang Y, Shu Y, Chen C, Lu Z, Cai W, Qiu W
Neurobiology of disease 2024 Dec;203:106744
Neurobiology of disease 2024 Dec;203:106744
DET1 modulates ATAF1-repressed thermosensory elongation through ubiquitination in Arabidopsis.
Yuan S, Li Y, Li Y, Wei J, Liu M, Yang F, Yao X
Plant cell reports 2024 Dec 17;44(1):7
Plant cell reports 2024 Dec 17;44(1):7
Methylene Blue Pretreatment Protects Against Repeated Neonatal Isoflurane Exposure-Induced Brain Injury and Memory Loss.
Wu C, Deng Q, Zhu L, Liu TC, Duan R, Yang L
Molecular neurobiology 2024 Aug;61(8):5787-5801
Molecular neurobiology 2024 Aug;61(8):5787-5801
Digirseophene A promotes recovery in injured developing cerebellum via AMPK/AKT/GSK3β pathway-mediated neural stem cell proliferation.
Tang X, Huang Y, Fu W, Wang P, Feng L, Yang J, Zhu H, Huang X, Ming Q, Li P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117046
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117046
Antidepressant effect of teriflunomide via oligodendrocyte protection in a mouse model.
Luo S, Wu F, Fang Q, Hu Y, Zhang H, Yuan S, Yang C, Shi Y, Luo Y
Heliyon 2024 Apr 30;10(8):e29481
Heliyon 2024 Apr 30;10(8):e29481
Sildenafil Enhances the Therapeutic Effect of Islet Transplantation for Diabetic Peripheral Neuropathy via mTOR/S6K1 Pathway.
Zhu X, Xie S, Chen J, Lu Q, Wang X, Duan F, Xu S, Zhang Y, Huang H, Wang Y, Wang H, Chen B, Huang H
International journal of endocrinology 2023;2023:8199029
International journal of endocrinology 2023;2023:8199029
PKCε activator protects hippocampal microvascular disruption and memory defect in 3×Tg-Alzheimer's disease mice with cerebral microinfarcts.
Wang H, Zhang Z, Hongpaisan J
Frontiers in aging neuroscience 2023;15:1272361
Frontiers in aging neuroscience 2023;15:1272361
The neuroprotective effect of dl-3-n-butylphthalide on the brain with experimental intracerebral hemorrhage.
Fang M, Hou H, Feng B, Zhang T, Zhu X, Liu Z
European journal of pharmacology 2023 Nov 15;959:176105
European journal of pharmacology 2023 Nov 15;959:176105
Engineered extracellular vesicles for delivery of siRNA promoting targeted repair of traumatic spinal cord injury.
Rong Y, Wang Z, Tang P, Wang J, Ji C, Chang J, Zhu Y, Ye W, Bai J, Liu W, Yin G, Yu L, Zhou X, Cai W
Bioactive materials 2023 May;23:328-342
Bioactive materials 2023 May;23:328-342
Bone marrow mesenchymal stem cells and exercise restore motor function following spinal cord injury by activating PI3K/AKT/mTOR pathway.
Sun X, Huang LY, Pan HX, Li LJ, Wang L, Pei GQ, Wang Y, Zhang Q, Cheng HX, He CQ, Wei Q
Neural regeneration research 2023 May;18(5):1067-1075
Neural regeneration research 2023 May;18(5):1067-1075
Brain-Derived Estrogen Regulates Neurogenesis, Learning and Memory with Aging in Female Rats.
Huang Y, Sun W, Gao F, Ma H, Yuan T, Liu Z, Liu H, Hu J, Bai J, Zhang X, Wang R
Biology 2023 May 23;12(6)
Biology 2023 May 23;12(6)
Mesenchymal stem cells transplantation combined with IronQ attenuates ICH-induced inflammation response via Mincle/syk signaling pathway.
Yang G, Kantapan J, Mazhar M, Bai X, Zou Y, Wang H, Huang B, Yang S, Dechsupa N, Wang L
Stem cell research & therapy 2023 May 15;14(1):131
Stem cell research & therapy 2023 May 15;14(1):131
Baicalin facilitates remyelination and suppresses neuroinflammation in rats with chronic cerebral hypoperfusion by activating Wnt/β-catenin and inhibiting NF-κB signaling.
Xiao Y, Guan T, Yang X, Xu J, Zhang J, Qi Q, Teng Z, Dong Y, Gao Y, Li M, Meng N, Lv P
Behavioural brain research 2023 Mar 28;442:114301
Behavioural brain research 2023 Mar 28;442:114301
Neuroprotective effect of aloe emodin against Huntington's disease-like symptoms in R6/1 transgenic mice.
Yan N, Wang S, Gao H, Chen J, Cao J, Wei P, Li X, Yu Y, Wang Y, Niu Y, Wang Y, Liu S, Jin G
Food & function 2023 Jun 6;14(11):5205-5216
Food & function 2023 Jun 6;14(11):5205-5216
Macrophage lineage cells-derived migrasomes activate complement-dependent blood-brain barrier damage in cerebral amyloid angiopathy mouse model.
Hu M, Li T, Ma X, Liu S, Li C, Huang Z, Lin Y, Wu R, Wang S, Lu D, Lu T, Men X, Shen S, Huang H, Liu Y, Song K, Jian B, Jiang Y, Qiu W, Liu Q, Lu Z, Cai W
Nature communications 2023 Jul 4;14(1):3945
Nature communications 2023 Jul 4;14(1):3945
Sigma-1 Receptor Activation Improves Oligodendrogenesis and Promotes White-Matter Integrity after Stroke in Mice with Diabetic Mellitus.
Song W, Yao Y, Zhang H, Hao X, Zhou L, Song Z, Wei T, Chi T, Liu P, Ji X, Zou L
Molecules (Basel, Switzerland) 2023 Jan 2;28(1)
Molecules (Basel, Switzerland) 2023 Jan 2;28(1)
Spatial and temporal alterations of developing oligodendrocytes induced by repeated sevoflurane exposure in neonatal mice.
Zhang Z, Liu H, Jia S, Zhao J, Wang J, Liu Y, Zhou F, Li Q, Li Z, Dong H, Zeng Y, Zhang R, Zhong H
Biochemical and biophysical research communications 2023 Jan 15;640:12-20
Biochemical and biophysical research communications 2023 Jan 15;640:12-20
Remyelination in neuromyelitis optica spectrum disorder is promoted by edaravone through mTORC1 signaling activation.
Luo W, Xu H, Xu L, Jiang W, Chen C, Chang Y, Liu C, Tian Z, Qiu X, Xie C, Li X, Chen H, Lai S, Wu L, Cui Y, Tang C, Qiu W
Glia 2023 Feb;71(2):284-304
Glia 2023 Feb;71(2):284-304
Jatrorrhizine ameliorates Schwann cell myelination via inhibiting HDAC3 ability to recruit Atxn2l for regulating the NRG1-ErbB2-PI3K-AKT pathway in diabetic peripheral neuropathy mice.
Gong X, Gui Z, Ye X, Li X
Phytotherapy research : PTR 2023 Feb;37(2):645-657
Phytotherapy research : PTR 2023 Feb;37(2):645-657
Erythrocyte Plasma Membrane Lipid Composition Mirrors That of Neurons and Glial Cells in Murine Experimental In Vitro and In Vivo Inflammation.
Stanzani A, Sansone A, Brenna C, Baldassarro VA, Alastra G, Lorenzini L, Chatgilialoglu C, Laface I, Ferreri C, Neri LM, Calzà L
Cells 2023 Feb 9;12(4)
Cells 2023 Feb 9;12(4)
Supramolecular Hydrogel Microspheres of Platelet-Derived Growth Factor Mimetic Peptide Promote Recovery from Spinal Cord Injury.
Wu W, Jia S, Xu H, Gao Z, Wang Z, Lu B, Ai Y, Liu Y, Liu R, Yang T, Luo R, Hu C, Kong L, Huang D, Yan L, Yang Z, Zhu L, Hao D
ACS nano 2023 Feb 28;17(4):3818-3837
ACS nano 2023 Feb 28;17(4):3818-3837
Insulin-like Growth Factor-1 Prevents Hypoxia/Reoxygenation-Induced White Matter Injury in Sickle Cell Mice.
Hazra R, Hubert H, Little-Ihrig L, Ghosh S, Ofori-Acquah S, Hu X, Novelli EM
Biomedicines 2023 Feb 24;11(3)
Biomedicines 2023 Feb 24;11(3)
Rapamycin Exerts an Antidepressant Effect and Enhances Myelination in the Prefrontal Cortex of Chronic Restraint Stress Mice.
Zhang J, Li W, Yue Q, Liu L, Hou ST, Ju J
Neuroscience 2023 Dec 15;535:99-107
Neuroscience 2023 Dec 15;535:99-107
Neuron-Derived Exosomes Promote the Recovery of Spinal Cord Injury by Modulating Nerve Cells in the Cellular Microenvironment of the Lesion Area.
Xu Y, Zhu ZH, Xu X, Sun HT, Zheng HM, Zhang JL, Wang HH, Fang JW, Liu YZ, Huang LL, Song ZW, Liu JB
Molecular neurobiology 2023 Aug;60(8):4502-4516
Molecular neurobiology 2023 Aug;60(8):4502-4516
Ropivacaine microsphere-loaded electroconductive nerve dressings for long-acting analgesia and functional recovery following diabetic peripheral nerve injury.
Liang F, Yang Y, Chen Y, Xie J, Liu S, Tan Z, Tian L, Yu Z, Shi Z, Xie P, Ding H, Yang Q
Materials today. Bio 2023 Aug;21:100712
Materials today. Bio 2023 Aug;21:100712
Nattokinase Promotes Post-stroke Neurogenesis and Cognition Recovery via Increasing Circulating Irisin.
Wu H, Zhang Q, Xu P, Chen J, Duan L, Xu F, Zhang F
Journal of agricultural and food chemistry 2023 Aug 2;71(30):11418-11428
Journal of agricultural and food chemistry 2023 Aug 2;71(30):11418-11428
Apolipoprotein E Polymorphism Impacts White Matter Injury Through Microglial Phagocytosis After Experimental Subarachnoid Hemorrhage.
Li C, Lu P, Zhang L, He Y, Zhang L, Yang L, Zhang F, Kong X, Tao Q, Zhou J, Wu J, Peng T, Xie B, Jiang Y, Peng J
Neuroscience 2023 Aug 1;524:220-232
Neuroscience 2023 Aug 1;524:220-232
Lipid-accumulated reactive astrocytes promote disease progression in epilepsy.
Chen ZP, Wang S, Zhao X, Fang W, Wang Z, Ye H, Wang MJ, Ke L, Huang T, Lv P, Jiang X, Zhang Q, Li L, Xie ST, Zhu JN, Hang C, Chen D, Liu X, Yan C
Nature neuroscience 2023 Apr;26(4):542-554
Nature neuroscience 2023 Apr;26(4):542-554
FOXP3+ macrophage represses acute ischemic stroke-induced neural inflammation.
Cai W, Hu M, Li C, Wu R, Lu D, Xie C, Zhang W, Li T, Shen S, Huang H, Qiu W, Liu Q, Lu Y, Lu Z
Autophagy 2023 Apr;19(4):1144-1163
Autophagy 2023 Apr;19(4):1144-1163
Catalpol Regulates Oligodendrocyte Regeneration and Remyelination by Activating the GEF-Cdc42/Rac1 Signaling Pathway in EAE Mice.
Wu M, Kang Q, Kang Y, Tong Y, Yang T, Fan Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7074157
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7074157
ADSCs Combined with Melatonin Promote Peripheral Nerve Regeneration through Autophagy.
Zhang Z, Zhang M, Zhang Z, Sun Y, Wang J, Chang C, Zhu X, Li M, Liu Y
International journal of endocrinology 2022;2022:5861553
International journal of endocrinology 2022;2022:5861553
Behavioral and Molecular Consequences of Chronic Sleep Restriction During Development in Fragile X Mice.
Saré RM, Song A, Levine M, Lemons A, Loutaev I, Sheeler C, Hildreth C, Mfon A, Smith CB
Frontiers in neuroscience 2022;16:834890
Frontiers in neuroscience 2022;16:834890
Effect of β-hydroxybutyrate on behavioral alterations, molecular and morphological changes in CNS of multiple sclerosis mouse model.
Sun W, Wen M, Liu M, Wang Q, Liu Q, Li L, Siebert HC, Loers G, Zhang R, Zhang N
Frontiers in aging neuroscience 2022;14:1075161
Frontiers in aging neuroscience 2022;14:1075161
Novel recombinant protein flagellin A N/C attenuates experimental autoimmune encephalomyelitis by suppressing the ROS/NF-κB/NLRP3 signaling pathway.
Li L, Deng S, Liu M, Yang M, Li J, Liu T, Zhang T, Zhao Y, He M, Wu D, Xu Y
Frontiers in pharmacology 2022;13:956402
Frontiers in pharmacology 2022;13:956402
Delivery of Basic Fibroblast Growth Factor Through an In Situ Forming Smart Hydrogel Activates Autophagy in Schwann Cells and Improves Facial Nerves Generation via the PAK-1 Signaling Pathway.
Hu B, Zhang H, Xu M, Li L, Wu M, Zhang S, Liu X, Xia W, Xu K, Xiao J, Zhang H, Ni L
Frontiers in pharmacology 2022;13:778680
Frontiers in pharmacology 2022;13:778680
Enhanced effect of combining bone marrow mesenchymal stem cells (BMMSCs) and pulsed electromagnetic fields (PEMF) to promote recovery after spinal cord injury in mice.
Huang L, Sun X, Wang L, Pei G, Wang Y, Zhang Q, Liang Z, Wang D, Fu C, He C, Wei Q
MedComm 2022 Sep;3(3):e160
MedComm 2022 Sep;3(3):e160
HDAC3 Inhibitor RGFP966 Ameliorated Neuroinflammation in the Cuprizone-Induced Demyelinating Mouse Model and LPS-Stimulated BV2 Cells by Downregulating the P2X7R/STAT3/NF-κB65/NLRP3 Activation.
Sun W, Zhang N, Liu B, Yang J, Loers G, Siebert HC, Wen M, Zheng X, Wang Z, Han J, Zhang R
ACS chemical neuroscience 2022 Sep 7;13(17):2579-2598
ACS chemical neuroscience 2022 Sep 7;13(17):2579-2598
Stemazole Promotes Oligodendrocyte Precursor Cell Survival In Vitro and Remyelination In Vivo.
Zhu Y, Chen M, Zhang Y, Han M
International journal of molecular sciences 2022 Sep 15;23(18)
International journal of molecular sciences 2022 Sep 15;23(18)
Ginsenoside Rg1 promotes remyelination and functional recovery in demyelinating disease by enhancing oligodendrocyte precursor cells-mediated myelin repair.
Liu L, Du X, Yang Q, Li M, Ran Q, Liu Q, Yang L, Sun L, Guo Y, Li Y, Chen Y, Zhu X, Li Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Nov;106:154309
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Nov;106:154309
The divergent effects of astrocyte ceruloplasmin on learning and memory function in young and old mice.
Li ZD, Li H, Kang S, Cui YG, Zheng H, Wang P, Han K, Yu P, Chang YZ
Cell death & disease 2022 Nov 28;13(11):1006
Cell death & disease 2022 Nov 28;13(11):1006
Neutrophil Nanovesicle Protects against Experimental Autoimmune Encephalomyelitis through Enhancing Myelin Clearance by Microglia.
Shen S, Cheng X, Zhou L, Zhao Y, Wang H, Zhang J, Sun X, Wang Y, Shu Y, Xu Y, Tao Y, Li M, Lu Z, Cai W, Nie G, Qiu W
ACS nano 2022 Nov 22;16(11):18886-18897
ACS nano 2022 Nov 22;16(11):18886-18897
Expression and immunogenicity of nsp10 protein of porcine epidemic diarrhea virus.
Zhu L, Liu S, Zhuo Z, Lin Y, Zhang Y, Wang X, Kong L, Wang T
Research in veterinary science 2022 May;144:34-43
Research in veterinary science 2022 May;144:34-43
E3 ubiquitin ligase Triad1 promotes neuronal apoptosis by regulating the p53-caspase3 pathway after spinal cord injury.
Wu C, Zhang H, Hong H, Chen C, Chen J, Zhang J, Xue P, Jiang J, Cui Z
Somatosensory & motor research 2022 Mar;39(1):21-28
Somatosensory & motor research 2022 Mar;39(1):21-28
SPIONs mediated magnetic actuation promotes nerve regeneration by inducing and maintaining repair-supportive phenotypes in Schwann cells.
Liu T, Wang Y, Lu L, Liu Y
Journal of nanobiotechnology 2022 Mar 27;20(1):159
Journal of nanobiotechnology 2022 Mar 27;20(1):159
Development of a Chemical Cocktail That Rescues Mouse Brain Demyelination in a Cuprizone-Induced Model.
Lai PL, Ng CH, Wu CH, Lai CY, Schuyler SC, Wang V, Lin H, Lee YC, Chuang MH, Yang CH, Chen WJ, Huang HC, Lu J
Cells 2022 Mar 24;11(7)
Cells 2022 Mar 24;11(7)
Sensory neurons have an axon initial segment that initiates spontaneous activity in neuropathic pain.
Nascimento AI, Da Silva TF, Fernandes EC, Luz LL, Mar FM, Safronov BV, Sousa MM
Brain : a journal of neurology 2022 Jun 3;145(5):1632-1640
Brain : a journal of neurology 2022 Jun 3;145(5):1632-1640
C1q inhibits differentiation of oligodendrocyte progenitor cells via Wnt/β-catenin signaling activation in a cuprizone-induced mouse model of multiple sclerosis.
Gao Z, Zhang C, Feng Z, Liu Z, Yang Y, Yang K, Chen L, Yao R
Experimental neurology 2022 Feb;348:113947
Experimental neurology 2022 Feb;348:113947
Rewired glycosylation activity promotes scarless regeneration and functional recovery in spiny mice after complete spinal cord transection.
Nogueira-Rodrigues J, Leite SC, Pinto-Costa R, Sousa SC, Luz LL, Sintra MA, Oliveira R, Monteiro AC, Pinheiro GG, Vitorino M, Silva JA, Simão S, Fernandes VE, Provazník J, Benes V, Cruz CD, Safronov BV, Magalhães A, Reis CA, Vieira J, Vieira CP, Tiscórnia G, Araújo IM, Sousa MM
Developmental cell 2022 Feb 28;57(4):440-450.e7
Developmental cell 2022 Feb 28;57(4):440-450.e7
Preparation, Characterization, Evaluation of Neuroprotective Effect, and Related Mechanisms of Phosphatidylserine Emulsion in 5- and 12-Week Old Mice.
Liu B, Zhang N, Yang J, Sun W, Zhang R, Zheng X, Wang Z, Siebert HC, Han J
Journal of agricultural and food chemistry 2022 Feb 16;70(6):1852-1864
Journal of agricultural and food chemistry 2022 Feb 16;70(6):1852-1864
Dose optimization of intrathecal administration of human umbilical cord mesenchymal stem cells for the treatment of subacute incomplete spinal cord injury.
Cao TT, Chen H, Pang M, Xu SS, Wen HQ, Liu B, Rong LM, Li MM
Neural regeneration research 2022 Aug;17(8):1785-1794
Neural regeneration research 2022 Aug;17(8):1785-1794
An in vivo implementation of the MEX MRI for myelin fraction of mice brain.
Wilczynski E, Sasson E, Eliav U, Navon G, Nevo U
Magma (New York, N.Y.) 2022 Apr;35(2):267-276
Magma (New York, N.Y.) 2022 Apr;35(2):267-276
Multifunctional biomimetic hydrogel based on graphene nanoparticles and sodium alginate for peripheral nerve injury therapy.
Jin Y, Zhang W, Zhang Y, Yang Y, Fang Z, Song J, Qian Y, Yuan WE
Biomaterials advances 2022 Apr;135:212727
Biomaterials advances 2022 Apr;135:212727
The microbiota-gut-brain axis participates in chronic cerebral hypoperfusion by disrupting the metabolism of short-chain fatty acids.
Xiao W, Su J, Gao X, Yang H, Weng R, Ni W, Gu Y
Microbiome 2022 Apr 17;10(1):62
Microbiome 2022 Apr 17;10(1):62
Photobiomodulation Therapy Attenuates Anxious-Depressive-Like Behavior in the TgF344 Rat Model.
Yang L, Wu C, Tucker L, Dong Y, Li Y, Xu P, Zhang Q
Journal of Alzheimer's disease : JAD 2021;83(4):1415-1429
Journal of Alzheimer's disease : JAD 2021;83(4):1415-1429
Connexin43 promotes angiogenesis through activating the HIF-1α/VEGF signaling pathway under chronic cerebral hypoperfusion.
Yu W, Jin H, Sun W, Nan D, Deng J, Jia J, Yu Z, Huang Y
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2021 Oct;41(10):2656-2675
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2021 Oct;41(10):2656-2675
Transfer of α-synuclein from neurons to oligodendrocytes triggers myelin sheath destruction in methamphetamine administration mice.
Ding J, Huang J, Xia B, Hu S, Fan H, Dai J, Li Z, Wang J, Le C, Qiu P, Wang Y
Toxicology letters 2021 Nov 1;352:34-45
Toxicology letters 2021 Nov 1;352:34-45
Maternal high sugar and fat diet benefits offspring brain function via targeting on the gut-brain axis.
Wang D, Zhang H, Zeng M, Tang X, Zhu X, Guo Y, Qi L, Xie Y, Zhang M, Chen D
Aging 2021 Mar 26;13(7):10240-10274
Aging 2021 Mar 26;13(7):10240-10274
A five-m6A regulatory gene signature is a prognostic biomarker in lung adenocarcinoma patients.
Wu X, Sheng H, Wang L, Xia P, Wang Y, Yu L, Lv W, Hu J
Aging 2021 Mar 26;13(7):10034-10057
Aging 2021 Mar 26;13(7):10034-10057
A Novel Rat Model with Long Range Optic Nerve Injury to Study Retinal Ganglion Cells Endogenous Regeneration.
Zhang S, Liu B, Zhu H, Jin H, Gong Z, Qiu H, Xu M, Chen M, Nan K, Wu W
Neuroscience 2021 Jun 15;465:71-84
Neuroscience 2021 Jun 15;465:71-84
Evaluation of cytokines and structural proteins to analyze the pathology of febrile central nervous system disease.
Ikeda T, Tani N, Watanabe M, Hirokawa T, Ikeda K, Morioka F, Ishikawa T
Legal medicine (Tokyo, Japan) 2021 Jul;51:101864
Legal medicine (Tokyo, Japan) 2021 Jul;51:101864
The combined treatment of NAD(+) and atorvastatin ameliorates the development of experimental autoimmune encephalomyelitis in C57BL/6 mice.
Sun H, Wang J, Guo L, Wang Y, Zhang J, Wang J, Quan M, Li B
Journal of neuroimmunology 2021 Jan 15;350:577429
Journal of neuroimmunology 2021 Jan 15;350:577429
Intranasal administration of DHED protects against exhaustive exercise-induced brain injury in rats.
Peng G, Zheng H, Wu C, Wu C, Ma X, Xiong J, Hou J, Zhang L, Yang L, Pan H
Brain research 2021 Dec 1;1772:147665
Brain research 2021 Dec 1;1772:147665
Caffeic Acid Phenethyl Ester Protects against Experimental Autoimmune Encephalomyelitis by Regulating T Cell Activities.
Zhou Y, Wang J, Chang Y, Li R, Sun X, Peng L, Zheng W, Qiu W
Oxidative medicine and cellular longevity 2020;2020:7274342
Oxidative medicine and cellular longevity 2020;2020:7274342
Acupuncture Improves White Matter Perfusion and Integrity in Rat Model of Vascular Dementia: An MRI-Based Imaging Study.
Ma SM, Wang L, Su XT, Yang NN, Huang J, Lin LL, Shao JK, Yang JW, Liu CZ
Frontiers in aging neuroscience 2020;12:582904
Frontiers in aging neuroscience 2020;12:582904
Bixin Attenuates Experimental Autoimmune Encephalomyelitis by Suppressing TXNIP/NLRP3 Inflammasome Activity and Activating NRF2 Signaling.
Yu Y, Wu DM, Li J, Deng SH, Liu T, Zhang T, He M, Zhao YY, Xu Y
Frontiers in immunology 2020;11:593368
Frontiers in immunology 2020;11:593368
Subarachnoid transplantation of human umbilical cord mesenchymal stem cell in rodent model with subacute incomplete spinal cord injury: Preclinical safety and efficacy study.
Yang Y, Cao TT, Tian ZM, Gao H, Wen HQ, Pang M, He WJ, Wang NX, Chen YY, Wang Y, Li H, Lin JW, Kang Z, Li MM, Liu B, Rong LM
Experimental cell research 2020 Oct 15;395(2):112184
Experimental cell research 2020 Oct 15;395(2):112184
Deficiency of microglial Hv1 channel is associated with activation of autophagic pathway and ROS production in LPC-induced demyelination mouse model.
Chen M, Yang LL, Hu ZW, Qin C, Zhou LQ, Duan YL, Bosco DB, Wu LJ, Zhan KB, Xu SB, Tian DS
Journal of neuroinflammation 2020 Nov 6;17(1):333
Journal of neuroinflammation 2020 Nov 6;17(1):333
Sevoflurane anesthesia during pregnancy in mice induces cognitive impairment in the offspring by causing iron deficiency and inhibiting myelinogenesis.
Zuo Y, Li B, Xie J, Ma Z, Thirupathi A, Yu P, Gao G, Zhou J, Zhou C, Xu H, Chang Y, Shi Z
Neurochemistry international 2020 May;135:104693
Neurochemistry international 2020 May;135:104693
Arsenic trioxide ameliorates experimental autoimmune encephalomyelitis in C57BL/6 mice by inducing CD4(+) T cell apoptosis.
An K, Xue MJ, Zhong JY, Yu SN, Lan TS, Qi ZQ, Xia JJ
Journal of neuroinflammation 2020 May 6;17(1):147
Journal of neuroinflammation 2020 May 6;17(1):147
Triclosan induces zebrafish neurotoxicity by abnormal expression of miR-219 targeting oligodendrocyte differentiation of central nervous system.
Ling Y, Sun L, Wang D, Jiang J, Sun W, Ai W, Wang X, Wang H
Archives of toxicology 2020 Mar;94(3):857-871
Archives of toxicology 2020 Mar;94(3):857-871
Amelioration of clinical course and demyelination in the cuprizone mouse model in relation to ketogenic diet.
Zhang N, Liu C, Zhang R, Jin L, Yin X, Zheng X, Siebert HC, Li Y, Wang Z, Loers G, Petridis AK
Food & function 2020 Jun 24;11(6):5647-5663
Food & function 2020 Jun 24;11(6):5647-5663
Chronic Sleep Restriction in Developing Male Mice Results in Long Lasting Behavior Impairments.
Saré RM, Song A, Levine M, Lemons A, Loutaev I, Sheeler C, Hildreth C, Mfon A, Cooke S, Smith CB
Frontiers in behavioral neuroscience 2019;13:90
Frontiers in behavioral neuroscience 2019;13:90
Myelin Oligodendrocyte Glycoprotein-IgG Contributes to Oligodendrocytopathy in the Presence of Complement, Distinct from Astrocytopathy Induced by AQP4-IgG.
Fang L, Kang X, Wang Z, Wang S, Wang J, Zhou Y, Chen C, Sun X, Yan Y, Kermode AG, Peng L, Qiu W
Neuroscience bulletin 2019 Oct;35(5):853-866
Neuroscience bulletin 2019 Oct;35(5):853-866
Integral membrane protein 2A inhibits cell growth in human breast cancer via enhancing autophagy induction.
Zhou C, Wang M, Yang J, Xiong H, Wang Y, Tang J
Cell communication and signaling : CCS 2019 Aug 22;17(1):105
Cell communication and signaling : CCS 2019 Aug 22;17(1):105
Mesenchymal Stem Cell-Derived Exosomes Reduce A1 Astrocytes via Downregulation of Phosphorylated NFκB P65 Subunit in Spinal Cord Injury.
Wang L, Pei S, Han L, Guo B, Li Y, Duan R, Yao Y, Xue B, Chen X, Jia Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(4):1535-1559
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(4):1535-1559
Sigma-1 receptor activation alleviates blood-brain barrier dysfunction in vascular dementia mice.
Liu DY, Chi TY, Ji XF, Liu P, Qi XX, Zhu L, Wang ZQ, Li L, Chen L, Zou LB
Experimental neurology 2018 Oct;308:90-99
Experimental neurology 2018 Oct;308:90-99
Structural and visual functional deficits in a rat model of neuromyelitis optica spectrum disorders related optic neuritis.
Zhang Y, Bao Y, Qiu W, Peng L, Fang L, Xu Y, Yang H
Experimental eye research 2018 Oct;175:124-132
Experimental eye research 2018 Oct;175:124-132
ST8SIA2 promotes oligodendrocyte differentiation and the integrity of myelin and axons.
Szewczyk LM, Brozko N, Nagalski A, Röckle I, Werneburg S, Hildebrandt H, Wisniewska MB, Kuznicki J
Glia 2017 Jan;65(1):34-49
Glia 2017 Jan;65(1):34-49
Protective Effect of 17β-Estradiol Upon Hippocampal Spine Density and Cognitive Function in an Animal Model of Vascular Dementia.
Zhu Y, Zhang Q, Zhang W, Li N, Dai Y, Tu J, Yang F, Brann DW, Wang R
Scientific reports 2017 Feb 16;7:42660
Scientific reports 2017 Feb 16;7:42660
Treatment with NAD(+) inhibited experimental autoimmune encephalomyelitis by activating AMPK/SIRT1 signaling pathway and modulating Th1/Th17 immune responses in mice.
Wang J, Zhao C, Kong P, Sun H, Sun Z, Bian G, Sun Y, Guo L
International immunopharmacology 2016 Oct;39:287-294
International immunopharmacology 2016 Oct;39:287-294
Methylene blue alleviates experimental autoimmune encephalomyelitis by modulating AMPK/SIRT1 signaling pathway and Th17/Treg immune response.
Wang J, Zhao C, Kong P, Bian G, Sun Z, Sun Y, Guo L, Li B
Journal of neuroimmunology 2016 Oct 15;299:45-52
Journal of neuroimmunology 2016 Oct 15;299:45-52
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Myelin basic protein antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Myelin basic protein. This antibody recognizes human,mouse,rat antigen. The Myelin basic protein antibody has been validated for the following applications: ELISA, WB analysis.
