BS7698
antibody from Bioworld Technology, Inc
Targeting: SLPI
ALK1, ALP, BLPI, HUSI, HUSI-I, WAP4, WFDC4
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS7698 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- SLPI polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human SLPI.
- Description
- SLPI, secretory leukocyte protease inhibitor, is an enzyme that belongs to the Ï«-1 antitrypsin antiprotein family. Produced by epithelial cells, SLPI resides in parotid secretions, bronchial, nasal and cervical mucus, and seminal fluid. SLPI plays a primary role in the regulation of neutrophil-mediated inflammation. It does so through proteolysis and subsequent inhibition of the leukocyte serine proteases, including the neutrophil and pancreatic proteases. The promoter region of SLPI has been identified as binding site for IRF-1, interferon regulatory factor. Expression of SLPI is inhibited by IRF-1 co-expression, identifying SLPI as a target of IRF-1 regulation. SLPI also functions as a macrophage derived inhibitor of macrophage response to LPS by inhibiting the production of nitric oxide, which suggests the role of SLPI in LPS tolerance.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- WesternBlot (WB) analysis of SLPI polyclonal antibody